# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- CFEM PF05730.11 EGF96883.1 - 0.00044 20.3 0.5 0.2 11.8 0.1 2.3 2 0 0 2 2 2 2 CFEM domain NECFESHC PF16621.5 EGF96885.1 - 10 6.2 10.1 5.1 7.1 0.2 3.5 2 1 0 3 3 3 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 SWIM PF04434.17 EGF96886.1 - 0.00089 18.9 0.7 0.0016 18.1 0.7 1.4 1 0 0 1 1 1 1 SWIM zinc finger Lambda_Kil PF06301.11 EGF96887.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein Asparaginase_2 PF01112.18 EGF96888.1 - 0.063 12.3 2.3 0.079 12.0 2.3 1.1 1 0 0 1 1 1 0 Asparaginase Hid1 PF12722.7 EGF96888.1 - 0.46 8.5 1.8 0.5 8.4 1.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1682 PF07946.14 EGF96888.1 - 2.5 7.2 14.9 3.4 6.8 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Presenilin PF01080.17 EGF96888.1 - 4.4 6.0 4.5 5 5.8 4.5 1.1 1 0 0 1 1 1 0 Presenilin rRNA_processing PF08524.11 EGF96890.1 - 8.2 6.4 14.7 10 6.2 14.7 1.0 1 0 0 1 1 1 0 rRNA processing DUF2931 PF11153.8 EGF96891.1 - 1.3e-47 162.1 0.0 2.1e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2931) DUF2235 PF09994.9 EGF96891.1 - 3.6e-17 62.6 0.0 9.7e-09 35.0 0.0 3.3 3 0 0 3 3 3 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2345 PF10106.9 EGF96891.1 - 0.0078 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) Mn_catalase PF05067.12 EGF96892.1 - 3.5e-86 288.7 0.0 3.1e-85 285.6 0.0 1.9 1 1 0 1 1 1 1 Manganese containing catalase COQ7 PF03232.13 EGF96892.1 - 0.00012 21.8 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EGF96892.1 - 0.032 14.6 0.0 4.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Rubrerythrin TPR_19 PF14559.6 EGF96892.1 - 0.1 13.1 0.4 0.25 11.9 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PAS_12 PF18095.1 EGF96893.1 - 0.062 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain TFIIS_C PF01096.18 EGF96895.1 - 4.5e-16 58.4 7.9 7.8e-16 57.7 0.8 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 EGF96895.1 - 8.3e-06 25.7 4.4 0.032 14.2 0.7 2.4 2 0 0 2 2 2 2 Double zinc ribbon RNA_POL_M_15KD PF02150.16 EGF96895.1 - 8.4e-06 25.6 11.6 0.0003 20.6 2.5 3.1 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit IBR PF01485.21 EGF96895.1 - 0.00062 19.9 3.5 0.19 12.0 0.6 2.3 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain VP_N-CPKC PF11475.8 EGF96895.1 - 0.00097 19.0 1.3 1.1 9.3 0.1 2.7 2 0 0 2 2 2 2 Virion protein N terminal domain zf-ribbon_3 PF13248.6 EGF96895.1 - 0.0031 16.9 10.3 0.3 10.6 0.2 4.1 4 0 0 4 4 4 1 zinc-ribbon domain HypA PF01155.19 EGF96895.1 - 0.0054 16.7 6.1 0.27 11.3 0.2 3.0 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 EGF96895.1 - 0.0097 15.5 8.9 0.84 9.3 0.1 4.1 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 EGF96895.1 - 0.014 15.7 3.6 15 6.0 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon tRNA-synt_1f PF01921.18 EGF96895.1 - 0.016 14.2 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF2387 PF09526.10 EGF96895.1 - 0.028 14.6 2.9 0.35 11.0 0.5 2.5 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-TFIIB PF13453.6 EGF96895.1 - 0.037 13.4 1.8 0.037 13.4 1.8 2.4 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-H2C2_2 PF13465.6 EGF96895.1 - 0.054 14.0 0.4 0.054 14.0 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C4_Topoisom PF01396.19 EGF96895.1 - 0.065 13.0 10.8 4.9 7.0 0.2 3.7 4 0 0 4 4 3 0 Topoisomerase DNA binding C4 zinc finger eIF-5_eIF-2B PF01873.17 EGF96895.1 - 0.069 13.0 6.7 0.26 11.2 0.8 2.6 2 1 1 3 3 3 0 Domain found in IF2B/IF5 Zn-ribbon_8 PF09723.10 EGF96895.1 - 0.075 13.2 11.4 1 9.5 0.8 3.6 3 1 0 3 3 3 0 Zinc ribbon domain C1_4 PF07975.12 EGF96895.1 - 0.1 12.8 8.2 0.11 12.8 0.9 3.1 3 1 1 4 4 4 0 TFIIH C1-like domain zinc-ribbons_6 PF07191.12 EGF96895.1 - 0.13 12.2 6.6 1.9 8.5 1.6 2.7 2 1 0 2 2 2 0 zinc-ribbons Zn_Tnp_IS91 PF14319.6 EGF96895.1 - 0.17 11.9 6.3 4.7 7.3 0.1 3.2 2 1 1 3 3 3 0 Transposase zinc-binding domain Baculo_LEF5_C PF11792.8 EGF96895.1 - 0.17 11.6 0.0 0.17 11.6 0.0 2.6 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_13 PF09855.9 EGF96895.1 - 0.4 10.9 8.5 12 6.2 0.1 3.7 4 0 0 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-C2HC5 PF06221.13 EGF96895.1 - 0.51 10.4 5.5 1.2 9.2 0.5 3.0 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-AN1 PF01428.16 EGF96895.1 - 0.64 10.2 6.7 6.1 7.1 0.1 3.0 3 1 0 3 3 3 0 AN1-like Zinc finger zinc_ribbon_4 PF13717.6 EGF96895.1 - 0.7 9.9 8.9 1.1 9.3 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-IS66 PF13005.7 EGF96895.1 - 0.71 10.3 8.8 46 4.5 0.2 4.2 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 Auto_anti-p27 PF06677.12 EGF96895.1 - 1.2 9.3 12.1 1.7 8.9 5.5 3.6 3 1 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF3797 PF12677.7 EGF96895.1 - 1.4 8.8 12.8 1.9 8.4 0.0 3.7 2 2 2 4 4 4 0 Domain of unknown function (DUF3797) Ogr_Delta PF04606.12 EGF96895.1 - 1.8 8.6 8.9 0.26 11.3 2.8 2.6 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger DUF4379 PF14311.6 EGF96895.1 - 1.8 9.0 4.7 1.4 9.3 1.4 2.4 2 1 1 3 3 2 0 Probable Zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EGF96895.1 - 2.7 7.6 15.1 5.9 6.5 4.5 3.5 2 2 0 2 2 2 0 TFIIB zinc-binding Nudix_N_2 PF14803.6 EGF96895.1 - 3 7.9 11.9 17 5.4 0.2 4.1 2 2 2 4 4 4 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 EGF96895.1 - 3.2 7.6 17.5 0.77 9.6 0.8 3.9 3 1 0 3 3 3 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 EGF96895.1 - 3.6 7.4 14.1 28 4.6 0.1 4.2 4 0 0 4 4 4 0 A2L zinc ribbon domain zinc_ribbon_15 PF17032.5 EGF96895.1 - 4 8.3 9.9 22 5.9 1.1 3.2 1 1 1 2 2 2 0 zinc-ribbon family DNA_RNApol_7kD PF03604.13 EGF96895.1 - 6.2 6.6 7.5 15 5.4 0.2 3.0 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_1 PF14446.6 EGF96895.1 - 6.3 6.8 9.5 42 4.2 0.1 3.5 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 Lar_restr_allev PF14354.6 EGF96895.1 - 6.4 7.2 12.0 31 5.1 0.6 3.9 2 2 0 2 2 2 0 Restriction alleviation protein Lar GET2 PF08690.10 EGF96896.1 - 0.19 11.4 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4110 PF13422.6 EGF96897.1 - 0.11 12.6 0.1 0.3 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) CDC45 PF02724.14 EGF96898.1 - 0.31 9.3 3.8 0.34 9.2 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein MRC1 PF09444.10 EGF96898.1 - 0.58 10.7 7.4 2.2 8.8 7.5 1.7 1 1 1 2 2 2 0 MRC1-like domain CLZ PF16526.5 EGF96899.1 - 0.1 12.9 1.1 0.15 12.5 1.1 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 EGF96899.1 - 0.15 12.3 2.6 0.28 11.5 2.6 1.4 1 1 0 1 1 1 0 ABC transporter C-terminal domain Mito_carr PF00153.27 EGF96900.1 - 3.5e-07 30.1 0.0 3.7e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein DnaJ PF00226.31 EGF96904.1 - 3.8e-09 36.5 0.0 6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Syntaxin-6_N PF09177.11 EGF96905.1 - 0.089 13.4 0.2 2.3 8.8 0.0 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal MOZ_SAS PF01853.18 EGF96906.1 - 3.5e-15 56.1 0.1 4.1e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 MOZ/SAS family HTH_6 PF01418.17 EGF96906.1 - 0.0021 18.0 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family YIEGIA PF14045.6 EGF96906.1 - 0.0082 15.0 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 YIEGIA protein HTH_IclR PF09339.10 EGF96906.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.6 EGF96906.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ATP-synt_C PF00137.21 EGF96908.1 - 4.8e-13 49.2 9.4 5.7e-13 49.0 9.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit C Proton_antipo_M PF00361.20 EGF96909.1 - 1.3e-12 47.6 13.0 3.4e-07 29.8 2.3 3.9 1 1 1 2 2 2 2 Proton-conducting membrane transporter HXXEE PF13787.6 EGF96909.1 - 0.028 15.2 2.6 0.063 14.1 2.6 1.8 1 1 0 1 1 1 0 Protein of unknown function with HXXEE motif Oxidored_q2 PF00420.24 EGF96909.1 - 4 7.1 10.4 3.1 7.5 8.7 1.7 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L UL42 PF17638.2 EGF96910.1 - 1.2 9.1 4.5 2.6 8.1 1.1 2.5 2 1 0 2 2 2 0 HCMV UL42 FtsH_ext PF06480.15 EGF96911.1 - 0.054 13.9 0.0 0.078 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsH Extracellular NSP2-B_epitope PF14757.6 EGF96913.1 - 0.048 13.4 0.7 0.064 12.9 0.8 1.2 1 1 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein DS PF01916.17 EGF96917.1 - 4.4e-22 78.7 0.0 5e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Tim29 PF10171.9 EGF96918.1 - 0.0061 16.1 0.2 0.015 14.8 0.2 1.6 1 0 0 1 1 1 1 Translocase of the Inner Mitochondrial membrane 29 MAS20 PF02064.15 EGF96919.1 - 0.012 15.7 0.1 0.019 15.1 0.1 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor ACT_5 PF13710.6 EGF96919.1 - 0.037 13.9 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 ACT domain FAD_binding_4 PF01565.23 EGF96920.1 - 8e-10 38.6 0.2 1.1e-09 38.2 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Gal_mutarotas_2 PF13802.6 EGF96925.1 - 1.2e-08 35.1 0.1 1.7e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Galactose mutarotase-like Spermine_synth PF01564.17 EGF96926.1 - 2.1e-37 128.4 0.0 8.6e-21 74.2 0.0 2.6 2 1 1 3 3 3 2 Spermine/spermidine synthase domain Sacchrp_dh_C PF16653.5 EGF96926.1 - 4.1e-26 92.7 0.0 3.8e-24 86.2 0.0 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synt_N PF17284.2 EGF96926.1 - 5.6e-17 61.4 0.0 9.7e-17 60.6 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Sacchrp_dh_NADP PF03435.18 EGF96926.1 - 2.6e-12 47.1 0.1 5.1e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Dicty_REP PF05086.12 EGF96927.1 - 0.026 12.5 2.9 0.031 12.3 2.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 EGF96927.1 - 0.042 13.8 8.2 0.055 13.5 8.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Alpha_kinase PF02816.18 EGF96928.1 - 3.3e-13 50.2 0.0 5e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family ABC_tran PF00005.27 EGF96933.1 - 4.6e-14 53.1 0.0 5.9e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.6 EGF96933.1 - 0.00063 19.9 0.0 0.0029 17.8 0.0 2.0 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EGF96933.1 - 0.00071 19.5 3.7 0.0013 18.6 0.8 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF702 PF05142.12 EGF96934.1 - 0.031 14.7 4.0 0.065 13.7 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) CARMIL_C PF16000.5 EGF96934.1 - 0.66 9.5 11.9 0.14 11.8 3.3 2.2 2 0 0 2 2 2 0 CARMIL C-terminus Cu-oxidase PF00394.22 EGF96935.1 - 6.5e-07 29.6 0.0 7.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Multicopper oxidase DUF4148 PF13663.6 EGF96936.1 - 0.013 15.7 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) zf-CCHC_6 PF15288.6 EGF96937.1 - 0.024 14.5 0.1 0.064 13.1 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle Spore_GerAC PF05504.11 EGF96942.1 - 0.1 12.8 0.4 0.21 11.8 0.4 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal zf-CCHC_2 PF13696.6 EGF96942.1 - 0.22 11.4 1.2 0.35 10.7 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle SBE2 PF17076.5 EGF96944.1 - 0.0066 14.8 1.6 0.0096 14.2 1.6 1.1 1 0 0 1 1 1 1 SBE2, cell-wall formation Prp19 PF08606.11 EGF96944.1 - 0.23 11.5 0.7 0.8 9.7 0.1 2.2 2 0 0 2 2 2 0 Prp19/Pso4-like DUF3573 PF12097.8 EGF96944.1 - 0.71 8.6 3.1 1.2 7.9 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) S1FA PF04689.13 EGF96946.1 - 0.55 10.4 2.6 1.2 9.3 2.6 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA Ras PF00071.22 EGF96948.1 - 5.5e-26 91.1 0.0 2.1e-25 89.2 0.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGF96948.1 - 0.0031 17.7 0.1 0.0092 16.2 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Alpha_kinase PF02816.18 EGF96951.1 - 7.7e-15 55.5 0.1 9.5e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 Alpha-kinase family DUF309 PF03745.14 EGF96954.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF309) Retrotran_gag_2 PF14223.6 EGF96955.1 - 5.3e-08 32.6 0.2 1.5e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type TraK PF06586.11 EGF96956.1 - 0.051 13.3 0.4 0.071 12.8 0.4 1.2 1 0 0 1 1 1 0 TraK protein Cytochrom_B562 PF07361.11 EGF96956.1 - 0.63 10.7 5.4 0.63 10.7 2.1 2.3 1 1 1 2 2 2 0 Cytochrome b562 DUF4672 PF15716.5 EGF96958.1 - 0.95 9.1 3.6 1.8 8.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4672) Put_DNA-bind_N PF06971.13 EGF96960.1 - 0.17 11.9 0.1 0.4 10.8 0.1 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus zf-CCHC PF00098.23 EGF96962.1 - 0.0055 16.7 2.6 0.0055 16.7 2.6 1.8 2 0 0 2 2 2 1 Zinc knuckle Cathelicidins PF00666.17 EGF96962.1 - 0.029 14.7 0.0 0.072 13.4 0.0 1.7 1 0 0 1 1 1 0 Cathelicidin CD99L2 PF12301.8 EGF96963.1 - 3.6 7.8 9.7 8.8 6.6 9.7 1.6 1 0 0 1 1 1 0 CD99 antigen like protein 2 BRO1 PF03097.18 EGF96964.1 - 4.8e-43 147.5 0.0 5.2e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain SWIRM PF04433.17 EGF96964.1 - 0.067 13.5 0.0 0.098 13.0 0.0 1.3 1 0 0 1 1 1 0 SWIRM domain Iso_dh PF00180.20 EGF96965.1 - 0.00014 21.1 0.0 0.00017 20.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Acyl-CoA_dh_1 PF00441.24 EGF96969.1 - 1e-16 61.5 0.3 1.2e-16 61.2 0.3 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 EGF96969.1 - 0.00047 20.4 0.2 0.00064 20.0 0.2 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DMSP_lyase PF16867.5 EGF96970.1 - 0.055 13.1 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase NAM-associated PF14303.6 EGF96971.1 - 0.038 14.7 4.1 0.049 14.4 4.1 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4021 PF13213.6 EGF96972.1 - 3 7.9 8.2 10 6.2 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4021) DUF5355 PF17306.2 EGF96973.1 - 0.19 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5355) DUF1325 PF07039.11 EGF96974.1 - 2.5e-25 89.1 0.0 4e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain ParE_toxin PF05016.15 EGF96978.1 - 0.012 16.2 0.6 0.44 11.2 0.2 2.3 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE Glyco_hydro_12 PF01670.16 EGF96979.1 - 5.5e-09 36.3 0.1 7.4e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 CNH PF00780.22 EGF96980.1 - 0.15 11.7 0.0 0.3 10.6 0.0 1.5 2 0 0 2 2 2 0 CNH domain SprA-related PF12118.8 EGF96981.1 - 0.35 10.0 0.5 0.5 9.5 0.5 1.1 1 0 0 1 1 1 0 SprA-related family Myb_DNA-binding PF00249.31 EGF96984.1 - 3.7e-24 84.6 6.0 9.9e-12 44.9 1.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF96984.1 - 2.7e-22 78.8 8.3 5.8e-14 52.1 3.6 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EGF96984.1 - 0.0059 16.7 0.1 0.49 10.5 0.1 2.7 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EGF96984.1 - 0.094 12.7 1.4 9.2 6.3 0.0 2.7 2 1 1 3 3 3 0 SLIDE Keratin_B2 PF01500.17 EGF96986.1 - 0.034 14.1 3.3 0.037 14.0 0.9 2.3 2 1 1 3 3 3 0 Keratin, high sulfur B2 protein Endotoxin_N PF03945.14 EGF96988.1 - 0.0088 15.8 0.9 0.014 15.2 0.9 1.2 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain IL17R_fnIII_D1 PF16556.5 EGF96988.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Interleukin-17 receptor, fibronectin-III-like domain 1 Endonuc_Holl PF10107.9 EGF96988.1 - 0.015 15.1 2.0 0.025 14.4 2.0 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Cortex-I_coil PF09304.10 EGF96988.1 - 0.016 15.4 1.5 0.033 14.4 1.5 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil LCIB_C_CA PF18599.1 EGF96988.1 - 0.025 13.9 0.9 0.043 13.1 0.9 1.4 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases HNF_C PF09354.10 EGF96988.1 - 0.026 15.5 0.2 0.65 11.1 0.0 2.6 2 1 0 2 2 2 0 HNF3 C-terminal domain NinD PF17466.2 EGF96988.1 - 0.036 14.2 2.8 0.085 12.9 2.5 1.8 1 1 0 1 1 1 0 Family of unknown function zf-CCHC PF00098.23 EGF96988.1 - 0.064 13.4 5.1 0.098 12.8 0.9 2.8 2 0 0 2 2 2 0 Zinc knuckle Xin PF08043.12 EGF96988.1 - 0.11 12.2 2.3 0.87 9.3 0.5 2.7 2 0 0 2 2 2 0 Xin repeat zf-CCHC_4 PF14392.6 EGF96988.1 - 0.2 11.4 0.1 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 Zinc knuckle ZapB PF06005.12 EGF96988.1 - 3.2 8.2 6.3 12 6.4 6.3 1.9 1 1 0 1 1 1 0 Cell division protein ZapB YbaB_DNA_bd PF02575.16 EGF96988.1 - 4.7 7.5 8.2 13 6.1 0.2 3.2 2 1 0 3 3 3 0 YbaB/EbfC DNA-binding family Retrotran_gag_2 PF14223.6 EGF96989.1 - 0.00025 20.7 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Dicty_REP PF05086.12 EGF96989.1 - 0.049 11.6 0.0 0.064 11.2 0.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SRP68 PF16969.5 EGF96990.1 - 0.042 12.9 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 DUF3636 PF12331.8 EGF96990.1 - 0.064 13.1 0.1 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3636) VIR_N PF15912.5 EGF96992.1 - 5.7 6.5 9.1 8.6 5.9 9.1 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal HEV_ORF1 PF02444.16 EGF96993.1 - 0.071 13.7 1.4 0.73 10.4 0.1 2.2 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) DUF488 PF04343.13 EGF96993.1 - 1 10.0 6.0 0.86 10.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF488 IDO PF01231.18 EGF96995.1 - 8.6e-12 44.6 0.0 1.1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase PI3K_1B_p101 PF10486.9 EGF96999.1 - 2.4 5.8 15.0 4 5.1 15.0 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3292 PF11696.8 EGF96999.1 - 3.7 5.8 11.9 2.1 6.6 9.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) Nop14 PF04147.12 EGF96999.1 - 7.3 4.7 25.3 11 4.1 25.3 1.3 1 0 0 1 1 1 0 Nop14-like family Zn_clus PF00172.18 EGF97000.1 - 3.7e-05 23.8 2.8 5.1e-05 23.3 2.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiS-like PF14453.6 EGF97001.1 - 2.8e-06 27.3 3.9 34 4.6 0.1 6.3 6 0 0 6 6 6 0 ThiS-like ubiquitin BiPBP_C PF06832.12 EGF97001.1 - 1.1e-05 25.3 6.2 53 4.0 0.0 6.9 7 0 0 7 7 7 0 Penicillin-Binding Protein C-terminus Family Lac_bphage_repr PF06543.12 EGF97001.1 - 9e-05 22.4 5.6 54 3.9 0.0 6.7 7 0 0 7 7 7 0 Lactococcus bacteriophage repressor Oest_recep PF02159.15 EGF97001.1 - 0.0019 18.7 20.2 7.5 7.0 0.1 6.6 7 0 0 7 7 7 2 Oestrogen receptor MAPKK1_Int PF08923.10 EGF97001.1 - 0.002 18.0 2.0 1.9e+02 1.9 0.0 5.6 6 0 0 6 6 6 0 Mitogen-activated protein kinase kinase 1 interacting HMG_box_5 PF14887.6 EGF97001.1 - 0.0043 17.0 17.4 44 4.1 0.1 6.4 6 0 0 6 6 6 0 HMG (high mobility group) box 5 VAPB_antitox PF02697.14 EGF97001.1 - 0.019 15.7 13.9 2.6e+02 2.5 0.1 8.4 7 0 0 7 7 7 0 Putative antitoxin Flagellin_N PF00669.20 EGF97001.1 - 0.17 12.0 13.3 22 5.1 0.1 6.4 6 1 0 7 7 7 0 Bacterial flagellin N-terminal helical region DUF3708 PF12501.8 EGF97001.1 - 1.8 8.3 29.6 15 5.4 0.4 7.2 1 1 5 7 7 7 0 Phosphate ATP-binding cassette transporter Nicastrin PF05450.15 EGF97001.1 - 5.2 6.4 6.8 23 4.4 0.0 4.2 5 0 0 5 5 5 0 Nicastrin CotH PF08757.11 EGF97002.1 - 0.063 12.8 0.9 0.075 12.5 0.9 1.0 1 0 0 1 1 1 0 CotH kinase protein AIF_C PF14721.6 EGF97002.1 - 0.15 12.4 0.9 0.17 12.2 0.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term V_ATPase_I PF01496.19 EGF97002.1 - 0.54 8.1 2.2 0.57 8.0 2.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LRR_10 PF18805.1 EGF97004.1 - 0.072 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat DUF547 PF04784.14 EGF97006.1 - 0.16 12.0 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF547 Viral_P18 PF04521.13 EGF97008.1 - 0.37 10.6 4.4 0.083 12.7 0.7 1.9 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein EOS1 PF12326.8 EGF97008.1 - 2.3 8.1 4.1 1.8 8.5 2.8 1.5 2 0 0 2 2 2 0 N-glycosylation protein Zip PF02535.22 EGF97008.1 - 4.3 6.5 5.4 6.1 6.0 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 EGF97008.1 - 5.6 6.7 16.3 1.5 8.6 13.3 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 WD40 PF00400.32 EGF97011.1 - 0.00027 21.7 0.5 1 10.4 0.3 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat QLQ PF08880.11 EGF97015.1 - 0.049 13.4 0.2 0.13 12.0 0.2 1.8 1 0 0 1 1 1 0 QLQ Retrotran_gag_3 PF14244.6 EGF97016.1 - 0.072 12.9 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type TnpV PF14198.6 EGF97016.1 - 0.097 12.7 0.7 0.27 11.2 0.2 2.0 3 0 0 3 3 3 0 Transposon-encoded protein TnpV ORC6 PF05460.13 EGF97026.1 - 0.0012 18.3 2.3 0.0031 16.8 2.3 1.8 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Ndc1_Nup PF09531.10 EGF97026.1 - 0.31 9.7 2.1 0.47 9.1 2.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PRP21_like_P PF12230.8 EGF97029.1 - 1.6e-40 139.3 13.7 1.6e-40 139.3 13.7 2.4 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EGF97029.1 - 4.8e-33 112.9 1.7 2e-15 56.5 0.2 2.5 2 0 0 2 2 2 2 Surp module Gly_radical PF01228.21 EGF97029.1 - 0.053 14.1 0.5 0.16 12.5 0.5 1.9 1 0 0 1 1 1 0 Glycine radical zf_UBZ PF18439.1 EGF97029.1 - 0.058 13.0 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Noggin PF05806.12 EGF97029.1 - 0.52 10.2 3.0 1.4 8.8 3.0 1.7 1 0 0 1 1 1 0 Noggin Alpha_kinase PF02816.18 EGF97035.1 - 1.7e-10 41.3 0.0 8.2e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 Alpha-kinase family CxC5 PF18718.1 EGF97036.1 - 1.2e-33 115.7 4.6 1.9e-33 115.0 4.6 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 EGF97036.1 - 7.9e-05 22.5 0.3 7.9e-05 22.5 0.3 1.6 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases Pkinase PF00069.25 EGF97037.1 - 1.1e-18 67.5 0.0 1.2e-18 67.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF97037.1 - 1.3e-11 44.3 0.0 1.3e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2623 PF11115.8 EGF97037.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) Pkinase PF00069.25 EGF97038.1 - 0.0043 16.5 0.0 0.0043 16.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain ParA PF10609.9 EGF97040.1 - 2.2e-76 256.6 0.1 9.1e-76 254.6 0.1 1.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGF97040.1 - 2.9e-06 27.4 0.0 4e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EGF97040.1 - 4e-06 26.3 0.0 6e-05 22.4 0.0 2.1 1 1 1 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 EGF97040.1 - 0.00041 19.6 0.4 0.0013 17.9 0.4 1.9 1 1 0 1 1 1 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EGF97040.1 - 0.00078 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_31 PF13614.6 EGF97040.1 - 0.00097 19.1 0.0 0.0032 17.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGF97040.1 - 0.038 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain FAM199X PF15814.5 EGF97041.1 - 8 5.4 12.0 8.7 5.3 12.0 1.0 1 0 0 1 1 1 0 Protein family FAM199X Syntaxin-5_N PF11416.8 EGF97044.1 - 0.25 10.6 1.2 0.27 10.5 0.1 1.7 2 0 0 2 2 2 0 Syntaxin-5 N-terminal, Sly1p-binding domain Mito_carr PF00153.27 EGF97045.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein RIO1 PF01163.22 EGF97046.1 - 1.7e-28 99.5 1.3 2.5e-19 69.6 0.2 2.0 1 1 1 2 2 2 2 RIO1 family Glyco_hydro_7 PF00840.20 EGF97047.1 - 1.3e-203 676.6 12.0 1.5e-203 676.4 12.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 GBP_PSP PF02425.15 EGF97048.1 - 0.051 13.2 0.1 0.084 12.5 0.1 1.3 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide GYF PF02213.16 EGF97049.1 - 0.00056 19.5 0.4 0.0011 18.6 0.4 1.4 1 0 0 1 1 1 1 GYF domain Glyco_hydro_15 PF00723.21 EGF97051.1 - 5.5e-56 190.2 0.3 6.5e-56 190.0 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Adeno_52K PF03052.15 EGF97051.1 - 0.059 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa Methyltrn_RNA_2 PF04013.12 EGF97052.1 - 0.0082 15.9 0.0 0.039 13.6 0.0 2.0 2 0 0 2 2 2 1 Putative SAM-dependent RNA methyltransferase DUF3801 PF12687.7 EGF97052.1 - 1.2 9.2 7.9 0.23 11.5 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) V_ATPase_I PF01496.19 EGF97053.1 - 0.012 13.5 2.3 0.017 13.1 2.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.6 EGF97053.1 - 0.015 15.5 1.4 0.015 15.5 1.4 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) CheZ PF04344.13 EGF97053.1 - 0.33 10.8 7.2 0.71 9.8 7.2 1.6 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ FapA PF03961.13 EGF97053.1 - 1.6 7.3 6.2 2.3 6.7 6.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 EGF97053.1 - 3.4 7.7 5.7 2.3 8.3 3.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EGF97053.1 - 3.8 7.5 11.8 3.8 7.5 6.9 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sad1_UNC PF07738.13 EGF97056.1 - 2.7e-28 98.6 0.0 5.4e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF4201 PF13870.6 EGF97056.1 - 0.04 13.7 2.1 0.069 12.9 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.12 EGF97056.1 - 0.12 12.9 1.7 1.6 9.3 0.8 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 EGF97056.1 - 0.16 12.1 1.4 0.29 11.3 1.4 1.3 1 0 0 1 1 1 0 Tropomyosin like MerR-DNA-bind PF09278.11 EGF97056.1 - 0.17 12.4 2.5 46 4.7 0.0 3.4 3 0 0 3 3 3 0 MerR, DNA binding Snapin_Pallidin PF14712.6 EGF97056.1 - 0.25 11.8 3.7 2.1 8.8 2.2 2.4 2 0 0 2 2 2 0 Snapin/Pallidin BLOC1_2 PF10046.9 EGF97056.1 - 0.36 11.2 8.0 0.6 10.4 5.3 2.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TRPM_tetra PF16519.5 EGF97056.1 - 4.1 7.6 5.6 0.86 9.8 0.4 2.6 3 1 0 3 3 3 0 Tetramerisation domain of TRPM DivIC PF04977.15 EGF97056.1 - 5.2 6.9 7.2 5.8 6.8 0.2 3.1 2 1 1 3 3 3 0 Septum formation initiator Flavoprotein PF02441.19 EGF97058.1 - 2e-47 160.8 0.0 2.4e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein PAP2 PF01569.21 EGF97060.1 - 2.2e-22 79.3 2.2 2.2e-22 79.3 2.2 1.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EGF97060.1 - 0.11 12.1 11.2 0.35 10.6 1.1 2.7 2 1 0 2 2 2 0 PAP2 superfamily PolyA_pol PF01743.20 EGF97062.1 - 5.3e-09 36.6 0.1 1.5e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 Poly A polymerase head domain Helicase_C PF00271.31 EGF97067.1 - 6.8e-09 36.0 0.0 1.5e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain eIF3g PF12353.8 EGF97067.1 - 0.14 12.6 0.8 0.3 11.5 0.8 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G SHMT PF00464.19 EGF97068.1 - 1.1e-22 80.2 0.0 1.2e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase CBM64 PF18666.1 EGF97068.1 - 0.024 14.7 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate-binding module 64 SNAD2 PF18745.1 EGF97070.1 - 0.017 14.9 0.1 0.021 14.5 0.1 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 NusG_add PF18298.1 EGF97070.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 NusG additional domain MBOAT PF03062.19 EGF97071.1 - 4.4e-33 115.1 8.6 8e-33 114.2 8.5 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3244 PF11589.8 EGF97072.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) zf-C2H2_assoc3 PF16637.5 EGF97073.1 - 0.015 15.4 1.6 0.098 12.9 0.3 2.6 2 0 0 2 2 2 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz zf-CpG_bind_C PF12269.8 EGF97073.1 - 0.047 13.5 1.0 0.1 12.3 0.1 1.9 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Tho2 PF11262.8 EGF97073.1 - 0.78 8.9 7.5 0.39 9.9 3.4 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF733 PF05306.11 EGF97073.1 - 1.5 9.2 5.5 0.4 11.0 1.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF733) COG2 PF06148.11 EGF97074.1 - 0.00023 21.3 1.0 0.00048 20.2 0.6 1.7 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Apolipoprotein PF01442.18 EGF97074.1 - 0.0004 20.3 0.1 0.0008 19.3 0.1 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EGF97074.1 - 0.00064 19.8 1.5 0.0013 18.8 1.5 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Lipase_GDSL_3 PF14606.6 EGF97074.1 - 0.0065 16.6 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Mis14 PF08641.12 EGF97074.1 - 0.0098 16.2 0.3 0.025 14.9 0.1 1.8 1 1 0 1 1 1 1 Kinetochore protein Mis14 like CSN5_C PF18323.1 EGF97074.1 - 0.0098 16.8 0.0 0.12 13.3 0.0 2.7 1 1 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Fzo_mitofusin PF04799.13 EGF97074.1 - 0.01 15.4 1.7 0.022 14.3 1.7 1.4 1 0 0 1 1 1 0 fzo-like conserved region Use1 PF09753.9 EGF97074.1 - 0.015 15.0 0.4 0.023 14.4 0.4 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 Ferritin-like PF12902.7 EGF97074.1 - 0.026 14.4 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Ferritin-like Focal_AT PF03623.13 EGF97074.1 - 0.039 14.0 1.8 0.31 11.1 0.6 2.3 2 0 0 2 2 2 0 Focal adhesion targeting region NifU_N PF01592.16 EGF97074.1 - 0.05 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 NifU-like N terminal domain DUF1451 PF07295.11 EGF97074.1 - 0.12 12.5 0.9 0.23 11.5 0.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF883 PF05957.13 EGF97074.1 - 0.14 12.8 2.9 0.27 11.8 0.5 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.12 EGF97074.1 - 0.25 11.4 3.9 0.71 9.9 3.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EGF97074.1 - 0.67 10.2 2.5 2.1 8.7 2.2 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 EGF97074.1 - 1.2 9.6 3.4 9.6 6.8 3.4 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FAR1 PF03101.15 EGF97076.1 - 0.00019 22.1 0.7 0.00019 22.1 0.7 1.7 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.11 EGF97076.1 - 0.021 15.2 1.0 0.021 15.2 1.0 2.1 2 0 0 2 2 2 0 Transcription factor AFT OrsD PF12013.8 EGF97080.1 - 5.7e-05 23.5 2.4 0.0013 19.2 0.1 2.7 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D DUF1724 PF08350.10 EGF97080.1 - 0.053 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) zf-3CxxC PF13695.6 EGF97080.1 - 0.055 13.9 0.8 0.23 11.9 0.8 2.2 1 1 0 1 1 1 0 Zinc-binding domain zf-C2H2_jaz PF12171.8 EGF97080.1 - 2.3 8.6 6.1 2.2 8.7 2.6 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EGF97080.1 - 4 8.5 16.6 0.12 13.3 1.3 4.3 3 0 0 3 3 3 0 C2H2-type zinc finger CxC1 PF18802.1 EGF97081.1 - 0.026 14.7 0.2 0.11 12.6 0.2 2.1 1 1 1 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases NPV_P10 PF05531.12 EGF97083.1 - 0.033 14.7 0.2 0.12 12.8 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein EVI2A PF05399.11 EGF97086.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Acyl-CoA_dh_N PF02771.16 EGF97087.1 - 2.8e-24 86.0 0.0 5.2e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EGF97087.1 - 1.7e-23 83.5 0.0 2.5e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGF97087.1 - 6.9e-20 71.1 0.0 1.1e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGF97087.1 - 2.7e-05 24.4 0.0 0.00023 21.4 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MinC_C PF03775.16 EGF97088.1 - 0.026 14.5 7.3 20 5.3 0.1 4.4 3 2 1 4 4 4 0 Septum formation inhibitor MinC, C-terminal domain DEAD PF00270.29 EGF97090.1 - 1.5e-12 47.6 0.0 2.9e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OrsD PF12013.8 EGF97090.1 - 1.3e-07 32.1 0.2 1.3e-07 32.1 0.2 3.3 3 0 0 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D Helicase_C PF00271.31 EGF97090.1 - 1.5e-07 31.7 0.0 3.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF97090.1 - 0.019 14.9 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-C2H2 PF00096.26 EGF97090.1 - 0.22 12.1 0.1 0.22 12.1 0.1 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF97090.1 - 1.6 9.8 10.8 2.1 9.4 2.6 4.6 3 0 0 3 3 3 0 C2H2-type zinc finger Nuf2 PF03800.14 EGF97091.1 - 2.6e-13 50.3 0.0 2.9e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Nuf2 family KOG2701 PF09762.9 EGF97091.1 - 0.068 13.4 0.0 0.077 13.2 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) Exo_endo_phos_2 PF14529.6 EGF97099.1 - 0.037 13.9 3.0 0.07 13.0 3.0 1.6 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase BSP_II PF05432.11 EGF97099.1 - 0.22 11.2 9.5 0.29 10.8 9.5 1.3 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) ALMT PF11744.8 EGF97099.1 - 4.5 6.0 6.0 4.8 5.9 6.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter MIF4G PF02854.19 EGF97102.1 - 7.5e-29 100.9 15.0 1.7e-28 99.7 15.0 1.6 1 1 0 1 1 1 1 MIF4G domain IBD PF10416.9 EGF97102.1 - 0.24 11.4 6.2 1.1 9.2 1.2 2.8 3 0 0 3 3 3 0 Transcription-initiator DNA-binding domain IBD Retrotran_gag_3 PF14244.6 EGF97106.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HALZ PF02183.18 EGF97108.1 - 0.12 12.6 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper TRI9 PF08195.11 EGF97109.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 TRI9 protein SCP_3 PF17844.1 EGF97109.1 - 0.17 11.7 0.0 0.53 10.1 0.0 1.8 1 0 0 1 1 1 0 Bacterial SCP ortholog Keratin_B2 PF01500.17 EGF97109.1 - 6.1 6.8 8.2 0.93 9.5 2.6 2.4 3 0 0 3 3 3 0 Keratin, high sulfur B2 protein PAP_central PF04928.17 EGF97110.1 - 9.4e-10 37.9 0.0 1e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 Poly(A) polymerase central domain Alpha_kinase PF02816.18 EGF97115.1 - 3.2e-27 95.9 0.1 4.8e-27 95.3 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family TIMELESS PF04821.14 EGF97116.1 - 5.4e-09 35.7 0.2 5.4e-09 35.7 0.2 1.3 2 0 0 2 2 2 1 Timeless protein E7 PF00527.18 EGF97116.1 - 0.057 13.6 0.0 0.069 13.4 0.0 1.2 1 0 0 1 1 1 0 E7 protein, Early protein Oxidoreduct_C PF16490.5 EGF97118.1 - 0.095 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain PSCyt3 PF07627.11 EGF97120.1 - 0.019 15.2 0.1 0.6 10.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) SMI1_KNR4 PF09346.10 EGF97120.1 - 0.13 12.7 0.5 5.4 7.4 0.0 2.3 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) zf-WRNIP1_ubi PF18279.1 EGF97121.1 - 0.064 13.9 0.7 0.29 11.8 0.7 2.3 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF1509 PF07420.11 EGF97123.1 - 0.039 12.9 0.3 0.063 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Glyco_hydro_10 PF00331.20 EGF97124.1 - 3.2e-73 246.6 0.0 4.1e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 EGF97124.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase DsrD PF08679.11 EGF97124.1 - 0.82 10.0 5.9 8.3 6.8 0.9 2.8 3 0 0 3 3 3 0 Dissimilatory sulfite reductase D (DsrD) Rhodanese PF00581.20 EGF97125.1 - 5.8e-08 33.2 0.0 0.0016 18.9 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain T2SSM PF04612.12 EGF97125.1 - 0.049 13.7 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M MotCF PF09158.10 EGF97126.1 - 0.13 12.3 0.3 4.5 7.4 0.1 2.8 3 0 0 3 3 3 0 Bacteriophage T4 MotA, C-terminal FSAP_sig_propep PF03032.15 EGF97127.1 - 0.26 11.3 3.8 0.81 9.8 0.6 2.5 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide FAR1 PF03101.15 EGF97128.1 - 2e-05 25.2 0.3 3.9e-05 24.3 0.3 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain KDZ PF18758.1 EGF97129.1 - 5.9e-57 192.8 0.2 9.2e-57 192.2 0.2 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGF97129.1 - 6.1e-26 90.6 0.1 1.5e-25 89.3 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF97129.1 - 3.2e-10 40.1 0.0 6.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases PTR PF12789.7 EGF97129.1 - 0.15 12.2 0.0 0.53 10.4 0.0 1.9 2 0 0 2 2 2 0 Phage tail repeat like Uso1_p115_C PF04871.13 EGF97129.1 - 1.4 9.3 5.7 4.5 7.6 5.7 1.8 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region KDZ PF18758.1 EGF97133.1 - 7e-62 209.0 0.1 1.3e-61 208.1 0.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGF97133.1 - 1.2e-28 99.3 0.3 2.3e-28 98.4 0.3 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF97133.1 - 2.1e-09 37.5 0.0 4.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGF97133.1 - 0.0055 16.5 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases Aldo_ket_red PF00248.21 EGF97138.1 - 3.6e-37 128.1 0.0 4.9e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PBP1_TM PF14812.6 EGF97139.1 - 0.029 14.7 4.4 0.089 13.2 4.4 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GCP_C_terminal PF04130.13 EGF97139.1 - 0.037 13.5 0.2 0.065 12.7 0.2 1.4 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal SWIRM-assoc_2 PF16496.5 EGF97139.1 - 1.7 7.5 7.5 3.2 6.5 7.5 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal CxC1 PF18802.1 EGF97141.1 - 7.1e-15 55.0 0.1 1.8e-14 53.8 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF97141.1 - 5.5e-05 23.3 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases AAA_18 PF13238.6 EGF97142.1 - 0.093 13.3 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain CxC1 PF18802.1 EGF97144.1 - 2.5e-27 95.0 0.0 6.2e-27 93.8 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGF97144.1 - 0.00094 18.9 0.0 0.0026 17.4 0.0 1.7 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EGF97144.1 - 0.0049 17.0 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CemA PF03040.14 EGF97144.1 - 0.044 13.7 0.1 0.081 12.9 0.1 1.4 1 0 0 1 1 1 0 CemA family zf-CCHC PF00098.23 EGF97147.1 - 0.0042 17.1 2.0 0.0085 16.1 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle CcdA PF07362.12 EGF97148.1 - 0.033 14.6 0.5 5.2 7.6 0.1 2.5 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA DUF4164 PF13747.6 EGF97148.1 - 0.074 13.3 2.3 6.4 7.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) CRT10 PF08728.10 EGF97148.1 - 0.15 10.2 4.0 0.18 10.0 4.0 1.1 1 0 0 1 1 1 0 CRT10 Guanylin PF02058.15 EGF97148.1 - 0.63 10.6 3.3 2.8 8.5 1.2 2.4 2 0 0 2 2 2 0 Guanylin precursor WDCP PF15390.6 EGF97148.1 - 2.2 6.5 6.5 1.6 7.0 5.2 1.4 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SNF2_N PF00176.23 EGF97149.1 - 5.3e-44 150.4 4.5 5.9e-44 150.2 4.5 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGF97149.1 - 2e-08 34.4 0.1 2.4e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGF97149.1 - 1.3e-07 31.5 0.0 1.6e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGF97149.1 - 0.00038 20.2 0.0 0.00052 19.8 0.0 1.2 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Helicase_C PF00271.31 EGF97150.1 - 1.1e-14 54.7 0.0 1.6e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TnpV PF14198.6 EGF97150.1 - 0.016 15.2 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Transposon-encoded protein TnpV DUF2857 PF11198.8 EGF97150.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) NAM-associated PF14303.6 EGF97151.1 - 9.4 6.9 15.0 0.23 12.2 6.2 2.0 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain NPV_P10 PF05531.12 EGF97152.1 - 0.0031 17.9 4.7 0.0031 17.9 1.9 2.5 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EGF97152.1 - 0.032 14.5 0.9 0.1 12.9 0.3 2.1 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MICSWaP PF17018.5 EGF97152.1 - 0.033 13.7 0.3 0.063 12.8 0.3 1.4 1 0 0 1 1 1 0 Spore wall protein DUF848 PF05852.11 EGF97152.1 - 0.075 13.1 6.1 0.039 14.1 3.4 1.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FimH_man-bind PF09160.10 EGF97152.1 - 0.12 12.1 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 FimH, mannose binding HrpB7 PF09486.10 EGF97152.1 - 0.2 12.0 2.5 0.68 10.3 2.5 1.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) HsbA PF12296.8 EGF97152.1 - 0.24 11.9 7.0 2.7 8.5 0.1 3.3 3 0 0 3 3 3 0 Hydrophobic surface binding protein A LPP PF04728.13 EGF97152.1 - 0.68 10.4 2.8 28 5.2 0.1 2.8 1 1 1 2 2 2 0 Lipoprotein leucine-zipper ABC_tran_CTD PF16326.5 EGF97152.1 - 0.78 10.0 4.0 16 5.9 0.2 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF1664 PF07889.12 EGF97152.1 - 1.1 9.3 7.0 0.3 11.1 1.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.11 EGF97152.1 - 1.7 8.7 8.8 3.6 7.7 3.6 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SlyX PF04102.12 EGF97152.1 - 1.9 9.2 8.3 5.5 7.7 0.2 2.6 1 1 1 2 2 2 0 SlyX Fzo_mitofusin PF04799.13 EGF97152.1 - 1.9 8.0 5.0 0.38 10.3 1.3 1.7 2 0 0 2 2 2 0 fzo-like conserved region Atg14 PF10186.9 EGF97152.1 - 6.1 5.8 11.0 0.4 9.7 1.7 2.6 2 2 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 EGF97152.1 - 8.1 6.5 10.2 0.42 10.6 3.2 2.4 3 0 0 3 3 3 0 Laminin Domain II ATP_transf PF09830.9 EGF97154.1 - 5.9e-18 64.8 0.1 1.1e-17 63.9 0.1 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4272 PF14094.6 EGF97155.1 - 0.0044 16.3 0.1 0.006 15.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4272) DASH_Ask1 PF08655.10 EGF97156.1 - 1.6e-26 91.9 0.0 2.6e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 SARAF PF06682.12 EGF97159.1 - 3.4e-16 59.8 0.3 6.5e-16 58.9 0.3 1.5 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Ribophorin_I PF04597.14 EGF97161.1 - 2.6e-105 353.2 0.0 3.1e-105 352.9 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I IFT57 PF10498.9 EGF97163.1 - 0.01 14.8 2.3 0.015 14.3 2.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Snapin_Pallidin PF14712.6 EGF97163.1 - 0.016 15.6 2.2 0.016 15.6 2.2 2.4 2 1 1 3 3 3 0 Snapin/Pallidin SOGA PF11365.8 EGF97163.1 - 0.069 14.3 2.5 0.15 13.2 2.5 1.6 1 0 0 1 1 1 0 Protein SOGA Syntaxin-6_N PF09177.11 EGF97163.1 - 0.086 13.4 3.3 0.13 12.9 2.4 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 EGF97163.1 - 0.092 12.8 2.0 0.15 12.1 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 EGF97163.1 - 0.54 8.8 5.8 0.83 8.2 5.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 EGF97163.1 - 0.9 8.4 8.9 1.4 7.8 8.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.5 EGF97163.1 - 2.8 8.3 9.8 4.2 7.7 1.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) REV PF00424.18 EGF97164.1 - 0.17 11.9 0.0 0.17 11.9 0.0 2.7 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) GCP_C_terminal PF04130.13 EGF97167.1 - 0.0043 16.6 10.4 0.01 15.3 10.4 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal His_Phos_1 PF00300.22 EGF97167.1 - 0.048 13.3 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) ANAPC2 PF08672.11 EGF97167.1 - 0.065 13.7 1.2 0.065 13.7 1.2 3.7 5 1 0 5 5 5 0 Anaphase promoting complex (APC) subunit 2 DUF3349 PF11829.8 EGF97167.1 - 0.076 13.8 1.6 0.34 11.7 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) Pex19 PF04614.12 EGF97167.1 - 0.14 11.9 12.9 0.81 9.4 12.8 2.2 1 1 0 1 1 1 0 Pex19 protein family PIN_8 PF18476.1 EGF97167.1 - 0.31 10.9 15.8 0.021 14.7 2.7 2.2 1 1 1 2 2 2 0 PIN like domain Pro_sub2 PF18513.1 EGF97167.1 - 0.4 10.9 5.0 0.49 10.6 0.1 3.1 2 2 1 3 3 3 0 Prodomain subtilisin 2 ET PF01684.16 EGF97170.1 - 0.33 11.3 2.8 5.6 7.4 1.0 2.4 2 0 0 2 2 2 0 ET module CxC5 PF18718.1 EGF97171.1 - 8.7e-29 100.0 6.7 1.2e-28 99.6 6.7 1.2 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 EGF97171.1 - 0.026 14.4 0.3 0.04 13.7 0.3 1.2 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases SIP1 PF04938.12 EGF97172.1 - 4.7e-23 82.1 0.0 6.6e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) RVT_3 PF13456.6 EGF97173.1 - 8.7e-08 32.0 0.0 5.1e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like Imm68 PF15583.6 EGF97173.1 - 0.12 12.6 0.0 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 68 DUF4305 PF14146.6 EGF97173.1 - 0.24 11.6 4.7 1.2 9.4 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) DUF3226 PF11536.8 EGF97174.1 - 0.0086 15.8 2.4 0.014 15.1 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) SURF6 PF04935.12 EGF97174.1 - 0.01 15.7 1.7 0.01 15.7 1.7 1.5 2 0 0 2 2 2 0 Surfeit locus protein 6 Fib_alpha PF08702.10 EGF97174.1 - 0.11 12.6 4.1 0.23 11.6 4.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HSBP1 PF06825.12 EGF97174.1 - 0.72 9.8 5.9 16 5.4 2.0 2.7 2 1 0 2 2 2 0 Heat shock factor binding protein 1 DUF4094 PF13334.6 EGF97174.1 - 1.5 9.3 5.3 36 4.9 1.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) TolA_bind_tri PF16331.5 EGF97174.1 - 2.3 8.4 10.2 4.4 7.4 5.9 2.6 2 1 0 2 2 2 0 TolA binding protein trimerisation Ribosomal_L28e PF01778.17 EGF97177.1 - 0.0074 17.0 0.3 0.0094 16.7 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family LPD24 PF18839.1 EGF97181.1 - 0.079 13.2 0.6 11 6.4 0.1 2.2 1 1 1 2 2 2 0 Large polyvalent protein associated domain 24 Myc_N PF01056.18 EGF97182.1 - 0.74 9.7 10.6 0.94 9.3 10.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Pept_S41_N PF18294.1 EGF97183.1 - 0.012 15.5 2.1 0.029 14.4 0.6 2.3 2 0 0 2 2 2 0 Peptidase S41 N-terminal domain EFG_C PF00679.24 EGF97187.1 - 2.9e-08 33.6 0.0 3e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 Elongation factor G C-terminus SHOCT PF09851.9 EGF97188.1 - 0.48 10.2 2.6 5.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Short C-terminal domain AAA_12 PF13087.6 EGF97190.1 - 1.4e-08 34.7 0.2 2.1e-08 34.1 0.2 1.2 1 0 0 1 1 1 1 AAA domain FAD_binding_4 PF01565.23 EGF97191.1 - 9.2e-27 93.5 2.4 1.5e-26 92.8 2.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGF97191.1 - 2.1e-14 53.4 1.2 4e-14 52.5 1.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like eIF_4G1 PF12152.8 EGF97191.1 - 0.091 13.0 0.1 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4G1 BBE PF08031.12 EGF97192.1 - 3.3e-14 52.7 1.2 6.2e-14 51.8 1.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EGF97192.1 - 0.0023 17.4 0.1 0.0025 17.2 0.1 1.3 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.23 EGF97193.1 - 6.8e-30 103.6 2.1 1.1e-29 103.0 2.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGF97193.1 - 9.2e-14 51.3 1.4 1.8e-13 50.4 1.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EGF97193.1 - 0.014 14.8 0.2 0.019 14.4 0.2 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Alpha_kinase PF02816.18 EGF97196.1 - 6.8e-08 32.8 0.1 9.9e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family Ank_2 PF12796.7 EGF97197.1 - 9.8e-07 29.3 0.0 2.6e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF97197.1 - 3.9e-06 27.3 0.0 9.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGF97197.1 - 1.2e-05 25.5 0.0 3.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 EGF97197.1 - 1.6e-05 25.1 0.0 3.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF97197.1 - 7.1e-05 22.9 0.0 0.00025 21.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Albumin_I_a PF16720.5 EGF97197.1 - 0.056 13.4 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Albumin I chain a Peptidase_C107 PF17222.3 EGF97197.1 - 0.062 12.3 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 Pkinase PF00069.25 EGF97199.1 - 2.4e-21 76.3 0.0 3.4e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF97199.1 - 0.00012 21.4 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Phage_int_SAM_1 PF02899.17 EGF97199.1 - 0.038 14.3 0.0 0.084 13.2 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Nefa_Nip30_N PF10187.9 EGF97200.1 - 0.03 14.7 0.1 7 7.1 0.0 2.9 2 1 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 SSP160 PF06933.11 EGF97200.1 - 0.21 9.8 7.2 0.32 9.1 7.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 LRR_4 PF12799.7 EGF97201.1 - 1.6e-22 79.2 58.0 9.3e-05 22.7 0.5 9.6 8 2 3 11 11 11 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF97201.1 - 6.8e-16 57.8 52.4 0.00067 19.4 5.7 9.0 5 3 4 9 9 9 8 Leucine rich repeat LRR_1 PF00560.33 EGF97201.1 - 1e-06 28.4 45.8 2 9.3 0.1 13.2 12 1 0 12 12 12 4 Leucine Rich Repeat LRR_6 PF13516.6 EGF97201.1 - 0.29 11.3 0.1 0.29 11.3 0.1 12.9 14 0 0 14 14 14 0 Leucine Rich repeat DUF445 PF04286.12 EGF97201.1 - 0.5 10.1 6.5 0.1 12.4 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF445) HMG_box PF00505.19 EGF97203.1 - 0.0027 18.1 0.1 0.0061 16.9 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGF97203.1 - 0.029 14.9 0.2 0.077 13.6 0.2 1.7 1 0 0 1 1 1 0 HMG-box domain SET PF00856.28 EGF97205.1 - 7e-06 26.5 0.0 1.6e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 SET domain KDZ PF18758.1 EGF97206.1 - 1.8e-25 89.9 0.0 3.3e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGF97206.1 - 1.7e-13 50.6 0.2 1.4e-08 34.8 0.1 2.4 1 1 1 2 2 2 2 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF97206.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases Dynamin_N PF00350.23 EGF97208.1 - 3.2e-05 24.0 0.0 4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Dynamin family Nop53 PF07767.11 EGF97212.1 - 0.023 14.1 16.1 0.029 13.8 16.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF3105 PF11303.8 EGF97212.1 - 0.032 14.4 0.2 0.053 13.7 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3105) DUF4604 PF15377.6 EGF97212.1 - 0.036 14.5 13.2 0.056 13.9 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF3043 PF11241.8 EGF97212.1 - 0.17 11.9 8.4 0.27 11.3 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) RR_TM4-6 PF06459.12 EGF97212.1 - 0.19 11.5 7.9 0.25 11.1 7.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MscS_TM PF12794.7 EGF97212.1 - 1.8 7.3 6.4 2.6 6.8 6.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Atg14 PF10186.9 EGF97212.1 - 2.6 7.0 10.4 3.7 6.5 10.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Polyketide_cyc PF03364.20 EGF97213.1 - 3.9e-17 62.7 0.0 4.6e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EGF97214.1 - 9.9e-16 58.1 0.0 1.3e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ysc84 PF04366.12 EGF97215.1 - 4e-26 91.3 0.1 7.3e-26 90.4 0.1 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SPP PF06550.11 EGF97215.1 - 0.13 11.7 0.1 0.19 11.1 0.1 1.1 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease LOH1CR12 PF10158.9 EGF97219.1 - 0.0082 16.2 0.6 0.019 15.0 0.6 1.6 1 0 0 1 1 1 1 Tumour suppressor protein BLOC1_2 PF10046.9 EGF97219.1 - 0.0095 16.2 1.3 0.027 14.8 1.3 1.7 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Noelin-1 PF12308.8 EGF97219.1 - 0.014 15.4 1.5 0.035 14.1 0.8 2.0 1 1 0 1 1 1 0 Neurogenesis glycoprotein IQCJ-SCHIP1 PF15157.6 EGF97219.1 - 0.016 15.0 0.5 0.032 14.1 0.5 1.4 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif ZapB PF06005.12 EGF97219.1 - 0.025 15.0 3.4 0.096 13.1 3.4 2.0 1 1 0 1 1 1 0 Cell division protein ZapB GAS PF13851.6 EGF97219.1 - 0.075 12.4 6.0 0.18 11.1 5.3 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.11 EGF97219.1 - 0.078 11.9 5.5 0.12 11.2 5.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) NPV_P10 PF05531.12 EGF97219.1 - 0.11 12.9 1.1 3.3 8.3 0.1 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein P_C10 PF14974.6 EGF97219.1 - 0.18 11.9 1.3 0.84 9.8 0.3 2.2 2 0 0 2 2 2 0 Protein C10 UPF0242 PF06785.11 EGF97219.1 - 0.46 10.6 4.5 0.89 9.6 4.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 EGF97219.1 - 0.46 11.1 6.8 5 7.8 1.2 2.7 1 1 1 2 2 2 0 SlyX DUF1664 PF07889.12 EGF97219.1 - 0.69 10.0 2.7 2.7 8.0 2.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_9 PF13371.6 EGF97220.1 - 0.064 13.4 0.1 0.17 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2852 PF11014.8 EGF97226.1 - 0.71 10.0 5.7 1.4 9.1 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) CxC1 PF18802.1 EGF97228.1 - 8.7e-23 80.5 0.3 4.3e-19 68.6 0.0 2.3 1 1 1 2 2 2 2 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGF97228.1 - 1.8e-21 76.8 1.0 3.1e-21 76.0 0.1 1.8 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EGF97228.1 - 1.9e-08 34.4 0.1 3.9e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGF97228.1 - 0.0012 18.7 0.6 0.015 15.1 0.1 2.3 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases DUF5559 PF17714.1 EGF97230.1 - 0.061 13.2 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5559) DUF1556 PF07590.11 EGF97232.1 - 9.9 6.6 11.4 13 6.2 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1556) MFS_1 PF07690.16 EGF97233.1 - 2.4e-19 69.5 15.3 7.2e-19 67.9 10.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGF97233.1 - 2.7e-05 23.7 3.5 3.4e-05 23.3 2.8 1.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 EGF97233.1 - 0.00043 19.3 10.7 0.0018 17.2 10.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EGF97233.1 - 0.0015 17.0 1.3 0.0024 16.4 1.3 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector CxC5 PF18718.1 EGF97235.1 - 9.8e-32 109.5 2.4 1.6e-31 108.8 2.4 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 EGF97235.1 - 0.029 14.2 0.3 0.069 13.0 0.0 1.7 2 0 0 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases FhuF_C PF11575.8 EGF97235.1 - 4.2 7.4 6.6 16 5.6 0.1 3.1 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain Uds1 PF15456.6 EGF97241.1 - 0.03 14.5 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 Up-regulated During Septation Podoplanin PF05808.11 EGF97243.1 - 3.9 7.5 5.8 3.2 7.8 4.4 1.7 1 1 0 1 1 1 0 Podoplanin LAP1C PF05609.12 EGF97243.1 - 5.6 5.9 16.2 6.4 5.7 16.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Arg_decarbox_C PF17944.1 EGF97247.1 - 0.096 13.3 0.6 0.24 12.0 0.6 1.7 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension CxC1 PF18802.1 EGF97248.1 - 9.3e-28 96.4 0.0 1.5e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGF97248.1 - 2e-22 79.9 0.1 2.9e-22 79.4 0.1 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EGF97248.1 - 1.1e-07 32.0 0.0 2.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGF97248.1 - 0.02 14.7 0.0 0.06 13.2 0.0 1.8 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases DNA_pol3_tau_5 PF12170.8 EGF97248.1 - 0.14 12.2 0.1 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III tau subunit V interacting with alpha zf-C2H2_12 PF18658.1 EGF97250.1 - 0.046 13.3 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger C2H2-type TMEM215 PF15746.5 EGF97254.1 - 0.013 14.9 2.6 0.015 14.8 2.6 1.1 1 0 0 1 1 1 0 TMEM215 family Bestrophin PF01062.21 EGF97256.1 - 4.5e-33 114.9 0.6 6e-19 68.5 0.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Zn_clus PF00172.18 EGF97259.1 - 1.2e-05 25.3 8.3 3.4e-05 23.9 8.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPX PF03105.19 EGF97259.1 - 0.87 9.4 12.8 1.2 9.0 12.8 1.3 1 0 0 1 1 1 0 SPX domain Ribosomal_L4 PF00573.22 EGF97261.1 - 1.3e-46 158.8 0.0 4.7e-46 156.9 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family dCMP_cyt_deam_1 PF00383.23 EGF97265.1 - 1.6e-25 88.9 0.5 2.3e-25 88.4 0.5 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGF97265.1 - 6.1e-11 42.2 0.0 1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EGF97265.1 - 0.071 13.2 0.4 0.13 12.3 0.4 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Ndc1_Nup PF09531.10 EGF97266.1 - 1.4 7.5 5.1 1.5 7.5 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FapA PF03961.13 EGF97267.1 - 0.0085 14.7 2.8 0.0094 14.6 2.8 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF745 PF05335.13 EGF97267.1 - 0.27 10.9 2.8 0.22 11.2 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF1053 PF06327.14 EGF97267.1 - 1.5 9.4 6.3 15 6.2 0.5 2.6 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1053) Zn_clus PF00172.18 EGF97268.1 - 4.7e-05 23.4 2.8 6.6e-05 22.9 2.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1071 PF06378.11 EGF97268.1 - 0.28 10.7 2.0 0.38 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1071) DUF3195 PF11424.8 EGF97270.1 - 0.072 13.2 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) DUF2170 PF09938.9 EGF97270.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) NTF2 PF02136.20 EGF97274.1 - 0.015 15.8 0.1 0.033 14.8 0.1 1.6 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain SUD-M PF11633.8 EGF97279.1 - 2.9e-05 23.8 1.4 0.24 11.1 0.1 3.8 1 1 2 3 3 3 3 Single-stranded poly(A) binding domain DUF3499 PF12005.8 EGF97279.1 - 0.15 12.7 0.5 6.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Prefoldin_2 PF01920.20 EGF97280.1 - 0.052 13.5 0.8 0.052 13.5 0.8 3.0 3 1 1 4 4 4 0 Prefoldin subunit SlyX PF04102.12 EGF97280.1 - 0.27 11.9 2.9 1.7 9.3 2.9 2.4 1 1 0 1 1 1 0 SlyX XhlA PF10779.9 EGF97280.1 - 0.38 11.0 2.3 0.69 10.2 1.2 2.0 2 1 0 2 2 2 0 Haemolysin XhlA Helicase_C PF00271.31 EGF97283.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.6 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Thioredoxin_5 PF13743.6 EGF97286.1 - 0.0085 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Importin_rep_6 PF18829.1 EGF97286.1 - 0.022 14.9 0.1 0.048 13.8 0.1 1.5 1 0 0 1 1 1 0 Importin repeat 6 STE3 PF02076.15 EGF97290.1 - 3.9e-72 242.9 15.5 4.4e-72 242.7 15.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF4010 PF13194.6 EGF97290.1 - 0.049 13.3 0.7 0.098 12.3 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Ribosomal_L20 PF00453.18 EGF97291.1 - 0.0025 17.9 0.1 3.7 7.7 0.0 3.1 3 0 0 3 3 3 2 Ribosomal protein L20 Thioredoxin_5 PF13743.6 EGF97295.1 - 0.15 11.7 0.1 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin CxC1 PF18802.1 EGF97296.1 - 5.2e-25 87.6 0.1 1.1e-24 86.5 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF97296.1 - 2.3e-11 43.8 0.0 5.5e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGF97296.1 - 0.0017 18.2 0.0 0.0081 16.0 0.0 2.0 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases Cdh1_DBD_1 PF18196.1 EGF97296.1 - 9.4 6.6 8.1 4 7.8 0.0 2.8 2 1 1 3 3 3 0 Chromodomain helicase DNA-binding domain 1 DUF948 PF06103.11 EGF97298.1 - 0.098 12.9 0.6 0.24 11.7 0.6 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 EGF97298.1 - 0.24 12.0 2.4 0.56 10.9 0.4 2.4 2 0 0 2 2 2 0 SlyX P4Ha_N PF08336.11 EGF97298.1 - 1.6 8.8 4.6 0.42 10.6 1.3 1.7 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Mitofilin PF09731.9 EGF97298.1 - 1.8 7.3 11.8 1.5 7.6 4.2 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein DUF2570 PF10828.8 EGF97301.1 - 0.42 10.5 4.6 3.6 7.4 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) GCM PF03615.15 EGF97309.1 - 0.00032 20.6 2.1 0.001 19.0 0.5 2.1 2 0 0 2 2 2 1 GCM motif protein SANT_DAMP1_like PF16282.5 EGF97312.1 - 1e-30 105.7 3.7 3e-30 104.2 3.7 1.9 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Viral_P18 PF04521.13 EGF97312.1 - 0.028 14.2 0.2 0.072 12.9 0.2 1.6 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Myb_DNA-binding PF00249.31 EGF97312.1 - 0.051 13.8 0.0 0.31 11.3 0.0 2.3 3 0 0 3 3 3 0 Myb-like DNA-binding domain MecA PF05389.12 EGF97312.1 - 0.052 13.2 0.2 0.052 13.2 0.2 2.6 2 1 0 2 2 2 0 Negative regulator of genetic competence (MecA) Myb_DNA-bind_6 PF13921.6 EGF97312.1 - 0.074 13.3 2.1 1 9.7 0.0 3.3 3 1 1 4 4 4 0 Myb-like DNA-binding domain DUF5598 PF18127.1 EGF97314.1 - 0.1 13.1 0.0 0.31 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5598) RR_TM4-6 PF06459.12 EGF97324.1 - 0.17 11.7 9.2 0.22 11.3 9.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CLN3 PF02487.17 EGF97324.1 - 0.4 9.7 2.0 0.47 9.4 2.0 1.1 1 0 0 1 1 1 0 CLN3 protein MMR_HSR1 PF01926.23 EGF97325.1 - 0.00064 19.8 0.0 0.00068 19.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SAP PF02037.27 EGF97326.1 - 0.03 14.1 0.1 0.065 13.0 0.1 1.6 1 0 0 1 1 1 0 SAP domain zf-RING_2 PF13639.6 EGF97327.1 - 5.6e-10 39.4 8.6 5.6e-10 39.4 8.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EGF97327.1 - 9.1e-08 31.7 8.0 9.1e-08 31.7 8.0 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGF97327.1 - 3.1e-07 30.2 9.3 6.2e-07 29.2 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF97327.1 - 1.4e-06 28.1 8.7 1.4e-06 28.1 8.7 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF97327.1 - 1.1e-05 25.4 6.0 2.8e-05 24.0 6.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGF97327.1 - 6.6e-05 23.1 10.2 6.6e-05 23.1 10.2 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGF97327.1 - 0.00021 21.2 7.8 0.00044 20.1 7.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGF97327.1 - 0.0004 20.2 5.9 0.00074 19.3 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LRRFIP PF09738.9 EGF97327.1 - 0.0013 18.3 0.3 0.0017 17.9 0.3 1.2 1 0 0 1 1 1 1 LRRFIP family NAM-associated PF14303.6 EGF97327.1 - 0.0027 18.4 0.3 0.0028 18.4 0.3 1.2 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Macoilin PF09726.9 EGF97327.1 - 0.0044 15.7 0.9 0.0044 15.7 0.9 1.1 1 0 0 1 1 1 1 Macoilin family Apt1 PF10351.9 EGF97327.1 - 0.0047 15.8 1.9 0.0047 15.8 1.9 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Prok-RING_4 PF14447.6 EGF97327.1 - 0.0069 16.2 7.4 0.017 14.9 7.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EGF97327.1 - 0.013 15.1 5.9 0.032 13.8 5.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Atracotoxin PF05353.11 EGF97327.1 - 0.019 15.0 0.5 0.038 14.0 0.5 1.5 1 0 0 1 1 1 0 Delta Atracotoxin RSRP PF17069.5 EGF97327.1 - 0.028 14.0 18.6 0.037 13.6 18.6 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CCDC106 PF15794.5 EGF97327.1 - 0.034 13.9 3.9 0.05 13.3 3.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Chorion_2 PF03964.15 EGF97327.1 - 0.061 14.2 8.9 0.11 13.4 8.9 1.4 1 0 0 1 1 1 0 Chorion family 2 zf-HC5HC2H PF13771.6 EGF97327.1 - 0.1 12.8 3.1 0.22 11.8 3.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain SR-25 PF10500.9 EGF97327.1 - 0.13 11.8 22.3 0.21 11.2 22.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-HC5HC2H_2 PF13832.6 EGF97327.1 - 0.15 12.3 3.2 0.29 11.3 3.2 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain RINGv PF12906.7 EGF97327.1 - 0.29 11.3 4.8 0.76 10.0 4.8 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EGF97327.1 - 0.36 11.0 4.9 1.1 9.4 4.9 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain AF-4 PF05110.13 EGF97327.1 - 0.66 8.0 18.2 0.79 7.7 18.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein zf-C3H2C3 PF17122.5 EGF97327.1 - 0.66 10.1 7.4 2.2 8.4 7.4 2.0 1 0 0 1 1 1 0 Zinc-finger Pex14_N PF04695.13 EGF97327.1 - 0.75 10.4 5.4 1.4 9.6 4.6 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RING-like PF08746.11 EGF97327.1 - 1.1 9.7 6.7 2.5 8.5 6.7 1.7 1 0 0 1 1 1 0 RING-like domain DUF4614 PF15391.6 EGF97327.1 - 1.2 9.1 15.3 1.6 8.7 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Period_C PF12114.8 EGF97327.1 - 1.4 8.5 16.0 2 7.9 16.0 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region BUD22 PF09073.10 EGF97327.1 - 1.6 8.0 9.0 2.2 7.6 9.0 1.1 1 0 0 1 1 1 0 BUD22 zf-C3HC4_4 PF15227.6 EGF97327.1 - 3.7 7.8 9.2 46 4.3 9.4 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGF97327.1 - 9.8 6.3 14.2 0.072 13.1 5.3 2.0 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger GCM PF03615.15 EGF97334.1 - 0.0021 18.0 2.5 0.0046 16.9 2.5 1.5 1 0 0 1 1 1 1 GCM motif protein DUF3039 PF11238.8 EGF97335.1 - 0.3 10.9 1.3 0.77 9.6 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) Med31 PF05669.12 EGF97338.1 - 2e-29 101.4 2.0 2.3e-29 101.2 2.0 1.1 1 0 0 1 1 1 1 SOH1 Leu_zip PF15294.6 EGF97339.1 - 0.00094 18.8 3.4 0.00094 18.8 3.4 1.5 2 0 0 2 2 2 1 Leucine zipper Sugarporin_N PF11471.8 EGF97339.1 - 0.077 13.0 2.5 0.18 11.8 2.5 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension FapA PF03961.13 EGF97339.1 - 0.26 9.9 8.0 0.016 13.8 2.9 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A CLZ PF16526.5 EGF97339.1 - 2 8.8 9.4 2.1 8.8 4.2 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 EGF97339.1 - 2.4 7.4 7.5 0.3 10.4 3.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ABC_tran_CTD PF16326.5 EGF97339.1 - 2.8 8.3 10.3 12 6.2 10.3 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain SKA1 PF07160.12 EGF97339.1 - 3.2 7.5 11.4 0.39 10.5 0.5 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF2203 PF09969.9 EGF97339.1 - 6.4 7.5 7.0 1.6 9.5 3.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) XhlA PF10779.9 EGF97339.1 - 8.1 6.7 7.2 20 5.5 0.8 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Lzipper-MIP1 PF14389.6 EGF97344.1 - 0.095 13.0 0.1 0.37 11.1 0.1 2.0 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 KCT2 PF17818.1 EGF97344.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.7 3 0 0 3 3 3 0 Keratinocyte-associated gene product Xol-1_GHMP-like PF09109.10 EGF97345.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like NKWYS PF10364.9 EGF97347.1 - 0.066 13.3 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein PCNA_C PF02747.15 EGF97349.1 - 4.9e-47 159.3 0.1 5.9e-47 159.0 0.1 1.1 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 EGF97349.1 - 9.9e-05 21.5 0.3 0.00012 21.2 0.3 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 RE_HpaII PF09561.10 EGF97349.1 - 0.023 14.1 0.2 0.027 13.8 0.2 1.1 1 0 0 1 1 1 0 HpaII restriction endonuclease PCNA_N PF00705.18 EGF97349.1 - 0.25 11.1 0.8 14 5.4 0.2 2.5 2 1 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain DUF2334 PF10096.9 EGF97350.1 - 0.023 14.4 0.2 0.025 14.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF188 PF02639.14 EGF97350.1 - 0.041 13.5 1.1 0.075 12.7 1.1 1.4 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 FidL_like PF15941.5 EGF97350.1 - 2.2 8.8 5.2 1.9 9.0 3.3 1.8 1 1 1 2 2 2 0 FidL-like putative membrane protein potato_inhibit PF00280.18 EGF97351.1 - 0.064 13.9 0.3 0.11 13.2 0.3 1.3 1 0 0 1 1 1 0 Potato inhibitor I family Sec62 PF03839.16 EGF97352.1 - 0.029 13.9 1.9 0.041 13.4 1.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF5102 PF17104.5 EGF97355.1 - 4.7e-11 43.3 0.2 5.6e-11 43.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Nrf1_activ_bdg PF10492.9 EGF97356.1 - 0.11 13.2 0.1 0.17 12.5 0.1 1.3 1 0 0 1 1 1 0 Nrf1 activator activation site binding domain SH3_1 PF00018.28 EGF97357.1 - 0.00027 20.5 0.0 0.00037 20.0 0.0 1.1 1 0 0 1 1 1 1 SH3 domain Amidase PF01425.21 EGF97358.1 - 3.3e-39 135.1 0.1 2.2e-20 73.1 0.0 2.0 1 1 1 2 2 2 2 Amidase DUF4551 PF15087.6 EGF97364.1 - 7.3 5.3 9.1 8.6 5.0 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MIF4G_like_2 PF09090.11 EGF97367.1 - 6.1 6.2 8.7 0.29 10.5 2.4 2.0 3 0 0 3 3 3 0 MIF4G like GatB_N PF02934.15 EGF97368.1 - 1.4e-14 54.1 0.2 9.2e-07 28.5 0.2 2.0 1 1 1 2 2 2 2 GatB/GatE catalytic domain Polysacc_deac_1 PF01522.21 EGF97370.1 - 1.4e-27 96.0 0.0 2.3e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGF97370.1 - 0.018 14.2 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Grg1 PF11034.8 EGF97372.1 - 7.8e-12 45.3 3.3 1e-11 44.9 3.3 1.1 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Zn_clus PF00172.18 EGF97373.1 - 1e-06 28.8 5.1 1.9e-06 27.9 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FOXP-CC PF16159.5 EGF97381.1 - 0.0031 18.1 2.2 2.5 8.8 0.5 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-TRAF PF02176.18 EGF97381.1 - 0.15 12.8 0.5 3.6 8.4 0.0 2.1 1 1 0 2 2 2 0 TRAF-type zinc finger zf-H2C2_2 PF13465.6 EGF97381.1 - 0.31 11.5 4.7 0.39 11.2 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger double domain IBR PF01485.21 EGF97381.1 - 0.42 10.9 2.2 2.5 8.4 2.2 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain P5CR_dimer PF14748.6 EGF97382.1 - 2.4e-37 127.3 4.5 2e-36 124.4 2.3 2.2 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EGF97382.1 - 7.7e-12 45.7 0.2 7.8e-09 36.0 0.1 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent AMP-binding PF00501.28 EGF97383.1 - 6.7e-22 77.7 0.0 4.3e-21 75.0 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme GBP_PSP PF02425.15 EGF97383.1 - 0.12 12.0 0.2 0.34 10.6 0.2 1.7 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide HMD PF03201.16 EGF97383.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF1176 PF06674.11 EGF97384.1 - 0.081 12.4 0.1 0.099 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Exo_endo_phos PF03372.23 EGF97385.1 - 8.6e-09 35.3 0.0 5.4e-08 32.6 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family S4 PF01479.25 EGF97386.1 - 2.1e-11 43.3 1.3 2.1e-11 43.3 1.3 2.7 3 0 0 3 3 3 2 S4 domain Alpha_kinase PF02816.18 EGF97388.1 - 2.4e-13 50.6 0.0 3.1e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family NST1 PF13945.6 EGF97390.1 - 4.3e-44 150.9 0.4 4.3e-44 150.9 0.4 6.3 4 3 2 6 6 6 2 Salt tolerance down-regulator PfkB PF00294.24 EGF97392.1 - 3.3e-15 56.2 0.0 5e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EGF97392.1 - 0.00035 20.0 0.0 0.0005 19.5 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DAO_C PF16901.5 EGF97394.1 - 8.3e-46 155.0 0.0 1.4e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase DAO PF01266.24 EGF97394.1 - 2.2e-18 67.0 0.0 4.2e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase EF-hand_7 PF13499.6 EGF97394.1 - 1.4e-07 31.8 0.0 8.9e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGF97394.1 - 8.7e-05 21.8 0.1 0.002 17.6 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGF97394.1 - 0.00028 20.6 0.0 0.0043 16.9 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EGF97394.1 - 0.002 17.9 0.0 0.008 16.0 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair PGDYG PF14083.6 EGF97394.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 PGDYG protein EF-hand_5 PF13202.6 EGF97394.1 - 0.022 14.3 0.2 0.054 13.0 0.2 1.7 1 0 0 1 1 1 0 EF hand DnaJ PF00226.31 EGF97396.1 - 9.3e-16 57.7 0.2 1.6e-15 56.9 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 EGF97396.1 - 3.5e-15 55.4 0.8 7.8e-15 54.4 0.8 1.6 1 0 0 1 1 1 1 CSL zinc finger Lum_binding PF00677.17 EGF97396.1 - 0.027 14.4 0.3 0.072 13.1 0.1 1.8 2 1 0 2 2 2 0 Lumazine binding domain Alpha_E3_glycop PF01563.16 EGF97396.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein SHE3 PF17078.5 EGF97397.1 - 0.0051 16.6 2.2 0.0063 16.3 2.2 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 CAF-1_p150 PF11600.8 EGF97397.1 - 0.07 12.8 11.7 0.087 12.5 11.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2797 PF10977.8 EGF97397.1 - 0.095 12.6 2.9 0.11 12.4 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) DUF702 PF05142.12 EGF97397.1 - 0.61 10.6 3.9 0.73 10.3 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Romo1 PF10247.9 EGF97398.1 - 4.1e-24 84.7 13.1 6.4e-24 84.1 13.1 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 EGF97398.1 - 0.0064 16.8 1.9 0.008 16.5 1.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RibD_C PF01872.17 EGF97399.1 - 8.4e-30 104.1 0.0 9.7e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DUF4214 PF13946.6 EGF97399.1 - 0.026 14.5 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) Aldolase PF01081.19 EGF97399.1 - 0.09 12.2 0.0 6.2 6.2 0.0 2.2 2 0 0 2 2 2 0 KDPG and KHG aldolase Helitron_like_N PF14214.6 EGF97400.1 - 0.021 15.1 0.9 0.038 14.2 0.9 1.4 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus DUF4889 PF16230.5 EGF97404.1 - 0.14 12.4 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) Apolipoprotein PF01442.18 EGF97405.1 - 0.00013 21.9 0.0 0.00065 19.6 0.0 2.0 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EGF97405.1 - 0.00041 20.4 4.4 0.00041 20.4 4.4 2.1 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus MnmE_helical PF12631.7 EGF97405.1 - 0.002 18.3 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 MnmE helical domain Med29 PF11568.8 EGF97405.1 - 0.0093 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 29 CENP-Q PF13094.6 EGF97405.1 - 0.011 16.0 0.8 0.033 14.4 0.8 1.9 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Use1 PF09753.9 EGF97405.1 - 0.016 15.0 3.1 0.028 14.1 3.1 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF1664 PF07889.12 EGF97405.1 - 0.034 14.2 2.2 0.092 12.8 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 EGF97405.1 - 0.039 14.2 0.3 2 8.7 0.3 3.0 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Phage_HK97_TLTM PF06120.11 EGF97405.1 - 0.07 12.3 1.6 0.14 11.3 1.6 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Transcrip_act PF04949.13 EGF97405.1 - 0.12 12.2 1.2 4.7 7.1 1.1 2.2 1 1 0 1 1 1 0 Transcriptional activator DUF1640 PF07798.11 EGF97405.1 - 0.15 12.1 4.2 0.19 11.7 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Prominin PF05478.11 EGF97405.1 - 0.22 9.4 1.0 1.2 7.0 0.7 2.1 3 0 0 3 3 3 0 Prominin FAM76 PF16046.5 EGF97405.1 - 0.35 10.2 0.5 0.49 9.7 0.5 1.2 1 0 0 1 1 1 0 FAM76 protein F-box-like PF12937.7 EGF97406.1 - 0.001 18.9 2.3 0.001 18.9 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGF97406.1 - 0.16 11.9 0.2 0.16 11.9 0.2 2.4 2 0 0 2 2 2 0 F-box domain Utp14 PF04615.13 EGF97410.1 - 1 7.9 32.5 1.2 7.6 32.5 1.0 1 0 0 1 1 1 0 Utp14 protein XhlA PF10779.9 EGF97413.1 - 0.085 13.1 2.5 0.81 9.9 0.3 2.6 2 0 0 2 2 2 0 Haemolysin XhlA FAM76 PF16046.5 EGF97413.1 - 0.47 9.8 4.7 0.81 9.0 4.7 1.3 1 0 0 1 1 1 0 FAM76 protein DUF16 PF01519.16 EGF97413.1 - 4.1 7.9 7.6 12 6.4 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 EGF97414.1 - 0.063 13.9 0.3 0.28 11.8 0.1 2.2 2 0 0 2 2 2 0 SlyX Peptidase_M3_N PF08439.10 EGF97418.1 - 0.035 14.4 3.5 0.093 13.0 3.3 1.8 1 1 1 2 2 2 0 Oligopeptidase F Glyco_hydro_42 PF02449.15 EGF97419.1 - 0.021 14.2 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 Beta-galactosidase Dynamin_N PF00350.23 EGF97420.1 - 1.4 9.0 3.9 0.39 10.8 0.2 2.0 3 0 0 3 3 3 0 Dynamin family DUF702 PF05142.12 EGF97422.1 - 0.14 12.6 2.0 0.24 11.8 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) AMP-binding PF00501.28 EGF97424.1 - 2.6e-28 98.8 0.0 3e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGF97424.1 - 5.3e-21 74.3 0.8 1.2e-20 73.2 0.8 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus TMP_2 PF06791.13 EGF97425.1 - 0.16 11.6 6.6 0.25 11.0 6.6 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein Borrelia_P83 PF05262.11 EGF97425.1 - 1.6 7.2 7.6 2.1 6.7 7.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CxC5 PF18718.1 EGF97429.1 - 1.7e-30 105.5 7.2 3e-30 104.7 7.2 1.4 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 EGF97429.1 - 5.4 6.9 6.9 0.3 10.9 0.7 2.0 3 0 0 3 3 3 0 CxC4 like cysteine cluster associated with KDZ transposases RHD3 PF05879.12 EGF97434.1 - 3.4e-16 58.6 1.0 4.6e-16 58.1 1.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 EGF97434.1 - 2.8e-06 27.5 0.0 4.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGF97434.1 - 0.00011 22.2 0.1 0.00022 21.3 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EGF97434.1 - 0.0015 18.8 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGF97434.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGF97434.1 - 0.05 13.5 0.0 0.053 13.4 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase FeoB_N PF02421.18 EGF97434.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B ATPase_2 PF01637.18 EGF97434.1 - 0.096 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Septin PF00735.18 EGF97434.1 - 0.12 11.6 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Septin Roc PF08477.13 EGF97434.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Melibiase_2 PF16499.5 EGF97435.1 - 1.2e-07 31.3 0.6 4.4e-05 22.8 0.0 2.2 1 1 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 EGF97435.1 - 1.5e-07 31.3 0.2 5e-07 29.7 0.2 1.9 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Glyco_hydro_30C PF17189.4 EGF97435.1 - 0.0041 17.3 0.0 6.1 7.2 0.0 2.7 2 1 1 3 3 3 2 Glycosyl hydrolase family 30 beta sandwich domain zf-C3HC4_3 PF13920.6 EGF97437.1 - 1.6e-06 27.9 1.6 2.3e-06 27.4 1.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF97437.1 - 4.3e-06 27.0 2.3 7.8e-06 26.1 2.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGF97437.1 - 1.2e-05 25.1 3.2 2.2e-05 24.2 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF97437.1 - 3e-05 23.9 3.0 4.9e-05 23.2 3.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGF97437.1 - 3.3e-05 24.0 2.4 6.3e-05 23.1 2.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGF97437.1 - 0.00013 21.9 2.7 0.00013 21.9 2.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGF97437.1 - 0.00026 20.7 7.4 0.0025 17.6 7.5 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF97437.1 - 0.0016 18.2 1.3 0.0031 17.3 1.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FYVE PF01363.21 EGF97437.1 - 0.0031 17.6 1.0 0.0052 16.9 1.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-MIZ PF02891.20 EGF97437.1 - 0.015 15.1 2.5 0.026 14.3 2.5 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 EGF97437.1 - 0.023 15.0 2.5 0.045 14.0 2.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Rtf2 PF04641.12 EGF97437.1 - 0.033 13.6 0.1 0.044 13.1 0.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_4 PF14570.6 EGF97437.1 - 0.05 13.4 1.4 0.074 12.9 1.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 EGF97437.1 - 0.11 12.4 1.5 0.34 10.8 1.5 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Rad50_zn_hook PF04423.14 EGF97437.1 - 0.31 10.9 1.7 0.39 10.6 0.2 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF4890 PF16231.5 EGF97438.1 - 0.048 14.2 0.4 0.048 14.2 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) DUF1571 PF07608.11 EGF97439.1 - 0.068 12.6 0.1 0.12 11.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1571) HypA PF01155.19 EGF97440.1 - 0.024 14.6 0.3 0.05 13.6 0.3 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Pkinase PF00069.25 EGF97441.1 - 0.042 13.2 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain GREB1 PF15782.5 EGF97442.1 - 9.4 3.2 9.9 14 2.7 9.9 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2456 PF10445.9 EGF97443.1 - 2.3e-21 75.7 4.6 4.5e-21 74.7 4.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) DUF4395 PF14340.6 EGF97443.1 - 0.049 14.0 0.8 0.2 12.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) zf-C2H2 PF00096.26 EGF97444.1 - 0.023 15.2 1.9 0.042 14.3 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF97444.1 - 0.042 14.7 0.9 0.21 12.5 0.9 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger DEAD PF00270.29 EGF97445.1 - 6.1e-15 55.4 0.0 1.7e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGF97445.1 - 0.0069 16.4 0.0 0.0069 16.4 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_PWI PF18149.1 EGF97445.1 - 0.02 15.0 0.4 0.02 15.0 0.4 2.0 1 1 1 2 2 2 0 N-terminal helicase PWI domain RAP1 PF07218.11 EGF97447.1 - 1.8 6.8 3.5 2.4 6.3 3.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cyt-b5 PF00173.28 EGF97449.1 - 5.4e-19 68.1 0.0 5.9e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Metallophos PF00149.28 EGF97450.1 - 1.9e-09 38.3 0.0 2.9e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FixQ PF05545.11 EGF97450.1 - 3.7 7.6 5.1 8 6.5 5.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ MetallophosC PF16370.5 EGF97451.1 - 0.012 15.8 0.0 0.019 15.2 0.0 1.3 1 1 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase O_Spanin_T7 PF17531.2 EGF97451.1 - 0.02 14.9 0.2 0.042 13.9 0.2 1.6 1 0 0 1 1 1 0 outer-membrane spanin sub-unit TMEM247 PF15444.6 EGF97453.1 - 0.096 12.7 0.3 0.22 11.5 0.3 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 DUF2917 PF11142.8 EGF97457.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Asn_synthase PF00733.21 EGF97459.1 - 2.2e-19 70.4 0.2 7.1e-13 48.9 0.0 3.2 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EGF97459.1 - 2.7e-09 37.0 0.0 7.3e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGF97459.1 - 1e-05 25.7 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGF97459.1 - 0.074 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein T2SSE PF00437.20 EGF97460.1 - 0.00019 20.6 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EGF97460.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGF97460.1 - 0.003 17.8 0.2 0.0088 16.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 EGF97460.1 - 0.0041 16.8 0.1 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EGF97460.1 - 0.015 15.6 0.1 0.039 14.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGF97460.1 - 0.068 13.7 1.1 0.58 10.7 0.1 2.4 1 1 1 2 2 2 0 ABC transporter Mannitol_dh PF01232.23 EGF97460.1 - 0.08 13.1 0.3 0.31 11.2 0.0 2.0 2 1 1 3 3 3 0 Mannitol dehydrogenase Rossmann domain AAA_16 PF13191.6 EGF97460.1 - 0.13 12.7 0.3 0.39 11.1 0.1 1.8 1 1 1 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EGF97460.1 - 6.8 7.1 6.2 3.9 7.9 0.4 2.2 1 1 1 2 2 2 0 AAA domain WD40 PF00400.32 EGF97466.1 - 1.2e-08 35.4 2.3 0.085 13.8 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Alpha_kinase PF02816.18 EGF97468.1 - 2e-07 31.3 0.3 2.7e-07 30.9 0.3 1.2 1 0 0 1 1 1 1 Alpha-kinase family DUF3857 PF12969.7 EGF97468.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) WD40 PF00400.32 EGF97475.1 - 1.5 9.9 3.3 1.1e+02 3.9 0.1 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat MaoC_dehydratas PF01575.19 EGF97477.1 - 1.7e-11 43.8 0.0 2.9e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain ETF_alpha PF00766.19 EGF97481.1 - 4.7e-29 100.3 0.0 6.9e-29 99.7 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 EGF97481.1 - 7.7e-05 22.7 0.1 0.0001 22.2 0.1 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF883 PF05957.13 EGF97482.1 - 0.00013 22.5 47.1 0.11 13.1 4.1 5.2 2 2 3 5 5 5 5 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EGF97482.1 - 0.00097 19.6 55.3 0.0092 16.5 16.4 6.2 1 1 3 4 4 4 3 YtxH-like protein Apolipoprotein PF01442.18 EGF97482.1 - 0.094 12.6 36.8 0.091 12.6 27.7 3.1 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 EGF97482.1 - 2 8.5 76.5 0.096 12.8 8.5 7.7 4 2 3 7 7 7 0 Late embryogenesis abundant protein ApoO PF09769.9 EGF97482.1 - 4.5 7.3 14.5 22 5.0 1.9 4.4 2 2 1 3 3 3 0 Apolipoprotein O Hydrolase_4 PF12146.8 EGF97483.1 - 0.0032 16.8 0.0 0.0033 16.7 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EGF97483.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase LIP PF03583.14 EGF97483.1 - 0.16 11.2 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Secretory lipase PRR22 PF15776.5 EGF97484.1 - 0.014 14.8 3.4 0.025 14.0 3.4 1.4 1 1 0 1 1 1 0 Proline-rich protein family 22 Iwr1 PF08574.10 EGF97485.1 - 0.0014 19.6 3.6 0.0022 18.9 0.3 2.9 3 0 0 3 3 3 1 Transcription factor Iwr1 DUF4107 PF13389.6 EGF97485.1 - 0.0072 16.5 0.5 0.028 14.6 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4107) Presenilin PF01080.17 EGF97485.1 - 0.32 9.7 1.5 1.1 7.9 1.0 1.9 2 0 0 2 2 2 0 Presenilin DUF1770 PF08589.10 EGF97487.1 - 0.0019 19.2 0.1 0.0019 19.2 0.1 1.7 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1770) Ribosomal_L27e PF01777.18 EGF97489.1 - 2.1e-38 130.6 1.1 2.8e-38 130.1 1.1 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EGF97489.1 - 0.0015 18.4 0.7 0.0015 18.4 0.7 1.9 2 0 0 2 2 2 1 KOW motif DUF4145 PF13643.6 EGF97491.1 - 0.056 13.6 0.0 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) PI-PLC-Y PF00387.19 EGF97491.1 - 0.32 11.3 1.6 0.5 10.7 1.6 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain Ebp2 PF05890.12 EGF97491.1 - 0.37 10.3 8.9 0.44 10.1 8.9 1.1 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 Mal_decarbox_Al PF16957.5 EGF97492.1 - 0.035 12.5 0.1 0.04 12.2 0.1 1.0 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter Late_protein_L1 PF00500.18 EGF97493.1 - 0.0083 15.0 0.0 0.0083 15.0 0.0 1.0 1 0 0 1 1 1 1 L1 (late) protein IpgD PF05925.12 EGF97494.1 - 0.016 13.8 0.5 0.024 13.2 0.5 1.2 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD Synaptonemal_3 PF15191.6 EGF97495.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 PDZ_3 PF17815.1 EGF97496.1 - 0.024 14.5 0.1 0.033 14.0 0.1 1.2 1 0 0 1 1 1 0 PDZ domain KorB PF08535.10 EGF97496.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 KorB domain Orthopox_B11R PF07033.11 EGF97496.1 - 0.15 11.9 2.3 0.5 10.2 0.0 2.7 1 1 2 3 3 3 0 Orthopoxvirus B11R protein Pex19 PF04614.12 EGF97498.1 - 0.018 14.8 4.6 0.035 13.9 4.6 1.5 1 0 0 1 1 1 0 Pex19 protein family Cdh1_DBD_1 PF18196.1 EGF97498.1 - 0.09 13.1 3.2 0.07 13.5 0.9 1.9 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 FliE PF02049.18 EGF97498.1 - 0.76 10.0 6.2 1.9 8.7 2.4 2.8 2 1 0 2 2 2 0 Flagellar hook-basal body complex protein FliE Pro_sub2 PF18513.1 EGF97498.1 - 1.2 9.4 4.7 0.44 10.7 0.2 2.6 3 1 0 3 3 3 0 Prodomain subtilisin 2 Allexi_40kDa PF05549.11 EGF97498.1 - 8 5.9 10.7 1.8 8.0 2.9 2.4 1 1 2 3 3 3 0 Allexivirus 40kDa protein API5 PF05918.11 EGF97500.1 - 1.9 7.2 7.3 2.6 6.8 7.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RTC PF01137.21 EGF97501.1 - 8.1e-45 152.7 0.0 9.3e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EGF97501.1 - 5.4e-34 116.8 0.0 8.3e-34 116.2 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain AA_permease PF00324.21 EGF97503.1 - 2.1e-28 99.1 12.6 2.6e-28 98.8 12.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGF97503.1 - 1.1e-06 27.8 7.2 1.2e-06 27.6 7.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF485 PF04341.12 EGF97503.1 - 0.5 10.4 2.6 0.29 11.1 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Hemerythrin PF01814.23 EGF97506.1 - 0.079 13.6 2.5 0.2 12.3 2.5 1.7 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Baculo_PEP_C PF04513.12 EGF97506.1 - 0.099 12.7 2.7 0.17 11.9 1.5 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PLA2_B PF01735.18 EGF97507.1 - 8.9e-87 291.5 0.0 3.4e-52 177.5 0.0 2.2 2 0 0 2 2 2 2 Lysophospholipase catalytic domain LegC3_N PF18654.1 EGF97512.1 - 0.44 9.7 4.6 0.85 8.8 4.6 1.4 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain FYVE PF01363.21 EGF97515.1 - 1.7 8.9 7.6 3.4 7.9 7.6 1.5 1 1 0 1 1 1 0 FYVE zinc finger PBP1_TM PF14812.6 EGF97516.1 - 0.039 14.3 4.8 0.11 12.9 4.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4502 PF14950.6 EGF97516.1 - 0.055 12.9 4.3 0.12 11.8 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) Nucleo_P87 PF07267.11 EGF97516.1 - 1.1 8.1 3.5 1.6 7.5 3.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 EGF97518.1 - 4.8e-18 64.8 0.0 4.8e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein CDC45 PF02724.14 EGF97519.1 - 0.001 17.5 0.0 0.0016 16.8 0.0 1.3 1 1 0 1 1 1 1 CDC45-like protein UCR_TM PF02921.14 EGF97522.1 - 2.3e-11 44.0 1.3 7.3e-11 42.4 1.3 1.8 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 EGF97522.1 - 1e-10 41.4 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain ABC_tran_CTD PF16326.5 EGF97524.1 - 0.13 12.5 0.3 0.13 12.5 0.3 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain DUF3987 PF13148.6 EGF97528.1 - 0.14 11.1 0.6 0.22 10.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) UIM PF02809.20 EGF97533.1 - 0.14 12.2 4.0 0.31 11.0 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin interaction motif Peptidase_M24 PF00557.24 EGF97535.1 - 1.4e-46 158.8 0.0 1.9e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGF97535.1 - 8.8e-42 141.7 0.0 1.4e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Frataxin_Cyay PF01491.16 EGF97538.1 - 0.011 15.8 0.1 0.055 13.6 0.0 1.9 2 0 0 2 2 2 0 Frataxin-like domain SRP-alpha_N PF04086.13 EGF97540.1 - 2.1 8.2 25.0 1.2 9.0 15.5 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal HMG_box PF00505.19 EGF97543.1 - 0.052 14.0 0.1 0.82 10.1 0.0 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box Helicase_C PF00271.31 EGF97545.1 - 6.4e-15 55.5 0.0 8.3e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CBP_GIL PF10995.8 EGF97546.1 - 0.044 12.5 0.0 0.05 12.3 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis GIL PSI_integrin PF17205.3 EGF97547.1 - 1.2 9.0 9.5 4.7 7.0 9.5 1.9 1 1 0 1 1 1 0 Integrin plexin domain adh_short_C2 PF13561.6 EGF97549.1 - 0.016 14.8 0.0 0.017 14.7 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RNase_PH_C PF03725.15 EGF97549.1 - 0.098 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Aldedh PF00171.22 EGF97553.1 - 3.3e-112 375.4 0.0 3.8e-112 375.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGF97553.1 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pox_VLTF3 PF04947.14 EGF97555.1 - 0.072 12.8 0.6 0.21 11.3 0.4 1.9 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like Prothymosin PF03247.14 EGF97555.1 - 0.16 12.4 39.6 0.57 10.7 26.2 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family TAP42 PF04177.12 EGF97555.1 - 0.69 9.0 12.3 1.8 7.6 12.3 1.7 1 0 0 1 1 1 0 TAP42-like family COG2 PF06148.11 EGF97557.1 - 0.05 13.7 0.8 0.12 12.5 0.7 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Use1 PF09753.9 EGF97557.1 - 0.059 13.1 0.5 0.083 12.6 0.5 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF445 PF04286.12 EGF97557.1 - 0.094 12.5 0.3 0.15 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Apolipoprotein PF01442.18 EGF97557.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DDE_3 PF13358.6 EGF97559.1 - 1.2e-07 31.6 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EGF97559.1 - 0.029 15.0 0.0 0.087 13.5 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain AAA_14 PF13173.6 EGF97559.1 - 0.046 13.8 0.2 0.86 9.6 0.1 2.1 1 1 1 2 2 2 0 AAA domain DUF4771 PF15995.5 EGF97560.1 - 0.22 11.8 3.0 0.32 11.2 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) Mucin PF01456.17 EGF97562.1 - 0.39 10.7 6.7 0.31 11.0 1.6 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3994 PF13159.6 EGF97564.1 - 0.11 13.0 0.0 15 6.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) Rop PF01815.16 EGF97565.1 - 0.19 11.6 1.1 19 5.2 0.4 2.2 2 0 0 2 2 2 0 Rop protein ZapB PF06005.12 EGF97566.1 - 0.00011 22.6 3.0 0.00016 22.1 3.0 1.2 1 0 0 1 1 1 1 Cell division protein ZapB DUF908 PF06012.12 EGF97566.1 - 3.8 6.8 5.9 4.7 6.5 5.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) HATPase_c_3 PF13589.6 EGF97568.1 - 0.0042 16.9 0.0 0.0047 16.8 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC45 PF02724.14 EGF97570.1 - 0.29 9.4 16.2 0.3 9.3 16.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 EGF97570.1 - 1.2 8.0 3.4 1.1 8.1 3.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 EGF97570.1 - 1.4 8.2 21.3 1.7 7.9 21.3 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 EGF97570.1 - 2.6 6.7 3.9 2.8 6.6 3.9 1.1 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 EGF97570.1 - 2.7 6.4 13.3 2.6 6.5 13.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Paf1 PF03985.13 EGF97570.1 - 3.3 6.6 20.9 4.1 6.3 20.9 1.1 1 0 0 1 1 1 0 Paf1 Na_trans_assoc PF06512.13 EGF97570.1 - 3.7 7.8 15.6 4.2 7.6 15.6 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated TFIIA PF03153.13 EGF97570.1 - 4.9 7.0 17.0 4.9 7.0 17.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.13 EGF97570.1 - 5.3 6.9 23.7 8 6.3 23.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 EGF97570.1 - 5.8 5.0 30.5 6.7 4.8 30.5 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EGF97570.1 - 9.7 5.4 25.4 15 4.8 25.4 1.3 1 0 0 1 1 1 0 NOA36 protein API5 PF05918.11 EGF97572.1 - 0.18 10.6 7.7 0.22 10.3 7.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SWIM PF04434.17 EGF97576.1 - 1.8e-05 24.3 8.6 0.0012 18.5 0.5 2.6 2 0 0 2 2 2 2 SWIM zinc finger TRAPPC-Trs85 PF12739.7 EGF97576.1 - 0.16 10.9 1.4 0.27 10.2 1.4 1.3 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DnaJ PF00226.31 EGF97581.1 - 1.3e-05 25.2 0.1 3.4e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 DnaJ domain BNIP3 PF06553.12 EGF97581.1 - 0.073 12.7 1.3 0.082 12.6 0.0 1.6 2 0 0 2 2 2 0 BNIP3 HAD_2 PF13419.6 EGF97582.1 - 8.2e-06 26.0 0.1 4.1e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGF97582.1 - 0.0031 17.8 0.0 0.0057 17.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGF97582.1 - 0.031 14.3 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 HAD-hyrolase-like CxC1 PF18802.1 EGF97584.1 - 2.8e-12 46.7 0.0 2.3e-07 30.9 0.0 2.4 1 1 1 2 2 2 2 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGF97584.1 - 0.0027 17.3 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Xpo1 PF08389.12 EGF97584.1 - 0.071 13.2 1.0 8 6.5 0.2 2.2 2 0 0 2 2 2 0 Exportin 1-like protein HSP70 PF00012.20 EGF97586.1 - 0.028 12.6 0.6 0.033 12.4 0.6 1.1 1 0 0 1 1 1 0 Hsp70 protein FlgD PF03963.14 EGF97587.1 - 0.09 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region Gln-synt_C PF00120.24 EGF97592.1 - 1.6e-12 47.1 0.0 2.4e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EGF97592.1 - 1.1e-11 44.2 0.0 1.9e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain CxC1 PF18802.1 EGF97594.1 - 0.014 15.6 0.1 0.026 14.7 0.1 1.5 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases RNA_bind PF08675.11 EGF97595.1 - 0.089 12.8 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 RNA binding domain RRM_1 PF00076.22 EGF97595.1 - 0.17 11.7 0.1 4.4 7.2 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ARPC4 PF05856.12 EGF97597.1 - 1.7e-74 249.0 0.5 1.9e-74 248.8 0.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Borrelia_P83 PF05262.11 EGF97598.1 - 0.00095 17.8 4.9 0.0011 17.6 4.9 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein DUF3395 PF11875.8 EGF97598.1 - 0.48 10.3 7.6 0.74 9.7 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) MAJIN PF15077.6 EGF97598.1 - 3.5 7.3 6.6 5.2 6.8 6.6 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Ras PF00071.22 EGF97600.1 - 4.9e-34 117.3 0.0 5.8e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF97600.1 - 3.8e-10 40.0 0.0 5.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF97600.1 - 0.0014 18.2 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 EGF97600.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF3449 PF11931.8 EGF97601.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) PAS_4 PF08448.10 EGF97601.1 - 0.067 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 PAS fold JLPA PF16668.5 EGF97602.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Adhesin from Campylobacter SPX PF03105.19 EGF97605.1 - 8 6.3 14.9 11 5.8 14.9 1.2 1 0 0 1 1 1 0 SPX domain Retrotran_gag_2 PF14223.6 EGF97606.1 - 4.5e-10 39.3 0.0 7.6e-10 38.6 0.0 1.3 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1170 PF06663.13 EGF97606.1 - 0.065 12.9 0.1 0.081 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1170) KDZ PF18758.1 EGF97607.1 - 1.9e-33 116.0 0.2 2.9e-26 92.5 0.1 2.5 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGF97607.1 - 2.8e-31 107.7 0.7 6.6e-31 106.6 0.7 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF97607.1 - 0.0048 17.0 0.3 0.016 15.4 0.3 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGF97607.1 - 0.006 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases HP1451_C PF18472.1 EGF97607.1 - 0.05 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 HP1451 C-terminal domain HMG_box_2 PF09011.10 EGF97608.1 - 0.007 16.9 0.6 0.017 15.7 0.6 1.6 1 0 0 1 1 1 1 HMG-box domain SNF2_N PF00176.23 EGF97610.1 - 4.3e-44 150.7 1.5 4.8e-44 150.5 1.5 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGF97610.1 - 3.2e-07 30.3 0.0 4e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGF97610.1 - 6.8e-07 29.5 0.0 9.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGF97610.1 - 0.00032 20.5 0.0 0.00037 20.2 0.0 1.3 1 1 0 1 1 1 1 SWI2/SNF2 ATPase Helicase_C PF00271.31 EGF97611.1 - 3.2e-15 56.4 0.0 5.3e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PPDK_N PF01326.19 EGF97611.1 - 0.091 12.0 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Monellin PF09200.10 EGF97612.1 - 0.058 13.3 0.3 0.18 11.7 0.3 1.9 1 1 0 1 1 1 0 Monellin MULE PF10551.9 EGF97614.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 MULE transposase domain Mito_carr PF00153.27 EGF97620.1 - 1.3e-06 28.2 0.1 1.4e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Sec2p PF06428.11 EGF97621.1 - 0.038 14.0 0.1 2.6 8.1 0.0 2.5 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p KIAA1430 PF13879.6 EGF97623.1 - 0.78 10.5 5.8 1.5 9.6 5.8 1.5 1 0 0 1 1 1 0 KIAA1430 homologue Hid1 PF12722.7 EGF97623.1 - 0.98 7.5 5.0 1.1 7.3 5.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleo_P87 PF07267.11 EGF97623.1 - 1 8.1 4.7 0.65 8.8 3.3 1.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Suf PF05843.14 EGF97623.1 - 1.6 8.6 8.1 2.2 8.2 8.1 1.3 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) GREB1 PF15782.5 EGF97623.1 - 5.4 4.0 8.1 6.2 3.8 8.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CxC1 PF18802.1 EGF97624.1 - 4.8e-31 107.0 0.1 7.5e-31 106.4 0.1 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF97624.1 - 1.1e-08 35.1 0.0 2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGF97624.1 - 0.0055 16.3 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC3 PF18804.1 EGF97624.1 - 0.0086 15.9 0.1 0.24 11.3 0.0 2.3 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases Sod_Cu PF00080.20 EGF97628.1 - 7e-07 29.5 0.3 3.1e-06 27.4 0.3 1.9 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PKHD_C PF18331.1 EGF97629.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain Protoglobin PF11563.8 EGF97631.1 - 0.004 17.1 0.0 0.0058 16.5 0.0 1.2 1 0 0 1 1 1 1 Protoglobin Nuc_sug_transp PF04142.15 EGF97632.1 - 1.2e-38 133.1 1.4 1.4e-38 132.9 1.4 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter SpoIIM PF01944.17 EGF97632.1 - 0.011 15.7 0.3 0.017 15.1 0.3 1.3 1 1 0 1 1 1 0 Stage II sporulation protein M Srg PF02118.21 EGF97632.1 - 0.02 14.6 2.8 0.028 14.1 2.8 1.2 1 0 0 1 1 1 0 Srg family chemoreceptor DUF2675 PF11247.8 EGF97633.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) Glyco_transf_28 PF03033.20 EGF97640.1 - 1.4e-28 99.7 0.0 2.5e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EGF97640.1 - 2.3e-08 33.3 0.0 8.2e-08 31.5 0.0 1.7 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EGF97640.1 - 0.062 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain STAC2_u1 PF16664.5 EGF97640.1 - 1.5 9.3 5.5 0.26 11.8 1.3 1.9 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 BSP_II PF05432.11 EGF97640.1 - 5.4 6.6 23.3 15 5.2 20.3 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) OAF PF14941.6 EGF97642.1 - 0.57 9.6 6.9 0.62 9.5 6.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator, Out at first Prenylcys_lyase PF07156.14 EGF97645.1 - 1.4e-65 221.8 0.0 2.1e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 EGF97645.1 - 5.6e-09 35.8 0.0 2.5e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGF97645.1 - 2.5e-06 27.6 0.0 5.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGF97645.1 - 0.0099 15.9 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGF97645.1 - 0.065 12.5 0.0 0.27 10.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGF97645.1 - 0.31 10.6 1.5 2.8 7.4 1.5 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase F_actin_cap_B PF01115.17 EGF97647.1 - 6.2e-101 337.0 0.2 7.2e-101 336.8 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 EGF97647.1 - 0.0015 18.0 0.1 0.0037 16.7 0.1 1.6 1 1 0 1 1 1 1 F-actin capping protein alpha subunit BK_channel_a PF03493.18 EGF97647.1 - 0.035 14.3 0.2 11 6.3 0.1 2.5 2 0 0 2 2 2 0 Calcium-activated BK potassium channel alpha subunit Acyl-CoA_dh_1 PF00441.24 EGF97649.1 - 3.9e-07 30.4 0.0 4.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 EGF97649.1 - 0.0039 17.5 0.0 0.0058 16.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3781 PF12636.7 EGF97650.1 - 0.048 13.5 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) SnoaL_2 PF12680.7 EGF97651.1 - 5.1e-06 27.1 0.1 7.1e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EGF97651.1 - 0.01 16.2 0.0 0.014 15.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) LRR_4 PF12799.7 EGF97653.1 - 8.6e-05 22.8 10.6 10 6.7 1.6 5.7 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF97653.1 - 0.026 14.3 7.1 0.38 10.5 0.7 5.1 7 0 0 7 7 7 0 Leucine rich repeat Proteasome PF00227.26 EGF97654.1 - 1.2e-51 174.9 0.0 1.6e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGF97654.1 - 7.2e-14 51.2 0.1 1.2e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Aldo_ket_red PF00248.21 EGF97658.1 - 1.1e-46 159.4 0.0 5.7e-46 157.1 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family DUF2110 PF09883.9 EGF97658.1 - 0.033 13.8 0.0 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) Myb_DNA-bind_3 PF12776.7 EGF97659.1 - 6.6e-06 27.0 0.4 1.2e-05 26.2 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF1284 PF06935.11 EGF97661.1 - 0.0071 16.8 2.2 0.0086 16.5 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1284) Nexin_C PF08628.12 EGF97661.1 - 0.065 13.8 0.2 6.9 7.3 1.0 2.4 2 1 0 2 2 2 0 Sorting nexin C terminal PAS PF00989.25 EGF97662.1 - 0.00074 19.5 0.0 0.0041 17.1 0.0 1.9 2 0 0 2 2 2 1 PAS fold Utp11 PF03998.13 EGF97666.1 - 7.9e-75 252.0 25.7 1e-74 251.6 25.7 1.1 1 0 0 1 1 1 1 Utp11 protein Rota_NS53 PF00981.17 EGF97666.1 - 0.0042 16.0 0.2 0.0069 15.3 0.2 1.4 1 0 0 1 1 1 1 Rotavirus RNA-binding Protein 53 (NS53) SLATT_5 PF18160.1 EGF97666.1 - 0.051 12.9 0.2 0.13 11.5 0.2 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 IZUMO PF15005.6 EGF97666.1 - 0.12 12.9 0.3 0.12 12.9 0.3 2.2 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Flu_NS2 PF00601.19 EGF97666.1 - 0.15 12.4 3.2 0.19 12.0 0.6 2.5 2 1 0 3 3 3 0 Influenza non-structural protein (NS2) Transformer PF06495.11 EGF97666.1 - 8.6 6.4 15.6 6.1 6.9 7.6 2.5 2 0 0 2 2 2 0 Fruit fly transformer protein DUF1514 PF07438.11 EGF97668.1 - 9.2 6.2 6.9 28 4.7 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1514) bZIP_1 PF00170.21 EGF97669.1 - 0.002 18.2 19.7 0.043 13.9 3.3 2.4 1 1 1 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.17 EGF97669.1 - 0.0058 17.1 15.1 0.011 16.3 15.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 EGF97669.1 - 0.26 11.4 21.1 0.54 10.4 21.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Atg14 PF10186.9 EGF97669.1 - 0.27 10.3 5.5 0.41 9.7 5.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CDT1_C PF16679.5 EGF97669.1 - 0.48 10.9 5.7 1 9.8 5.7 1.5 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Nop53 PF07767.11 EGF97669.1 - 1.2 8.5 9.6 1.8 7.9 9.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GIT_CC PF16559.5 EGF97669.1 - 1.8 8.5 4.5 4.1 7.3 4.5 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Bmt2 PF11968.8 EGF97670.1 - 6.8e-62 209.2 0.0 7.9e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 EGF97670.1 - 9.1e-10 38.6 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF97670.1 - 1.1e-05 26.0 0.0 2.2e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF97670.1 - 0.0014 19.2 0.0 0.004 17.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF97670.1 - 0.0065 17.2 0.0 0.013 16.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF97670.1 - 0.015 15.1 0.0 0.084 12.7 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Ig_C17orf99 PF17736.1 EGF97673.1 - 0.15 12.1 0.1 0.18 11.8 0.1 1.1 1 0 0 1 1 1 0 C17orf99 Ig domain Fibrillarin PF01269.17 EGF97674.1 - 1.5e-35 122.4 0.1 1.1e-19 70.4 0.0 2.0 1 1 1 2 2 2 2 Fibrillarin PhoD PF09423.10 EGF97678.1 - 2.4e-06 26.8 0.7 0.0019 17.3 0.0 2.1 1 1 1 2 2 2 2 PhoD-like phosphatase Memo PF01875.17 EGF97679.1 - 1.1e-20 73.9 0.0 1.3e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Colicin PF01024.19 EGF97680.1 - 0.0081 16.1 0.5 0.0081 16.1 0.5 2.1 1 1 0 2 2 2 1 Colicin pore forming domain Med15_fungi PF05397.12 EGF97680.1 - 0.025 14.9 2.7 0.042 14.1 2.7 1.4 1 0 0 1 1 1 0 Mediator complex subunit 15 LdpA_C PF12617.8 EGF97680.1 - 0.028 14.0 0.9 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal UPF0160 PF03690.13 EGF97680.1 - 0.074 12.7 4.2 0.088 12.4 4.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) CorA PF01544.18 EGF97680.1 - 0.12 11.7 6.7 0.16 11.3 6.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Prominin PF05478.11 EGF97680.1 - 0.21 9.5 5.7 0.26 9.2 5.7 1.1 1 0 0 1 1 1 0 Prominin DUF3552 PF12072.8 EGF97680.1 - 0.32 10.4 16.5 0.091 12.2 10.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) HIP1_clath_bdg PF16515.5 EGF97680.1 - 0.51 11.0 17.9 0.13 12.9 9.8 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 EGF97680.1 - 0.65 10.1 9.8 4 7.5 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 EGF97680.1 - 1.7 9.0 9.0 0.48 10.7 2.5 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein Muted PF14942.6 EGF97680.1 - 2.1 8.7 17.1 6.9 7.0 16.6 2.0 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Pkinase PF00069.25 EGF97681.1 - 6.5e-14 51.9 0.1 7.5e-14 51.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF97681.1 - 0.0046 16.3 0.0 0.0051 16.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EGF97681.1 - 0.16 10.9 0.1 0.22 10.4 0.1 1.3 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase DNA_pol_phi PF04931.13 EGF97683.1 - 0.82 7.7 11.4 0.93 7.5 11.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi LRIF1 PF15741.5 EGF97683.1 - 1.7 7.1 22.0 2 6.9 22.0 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 FAM76 PF16046.5 EGF97683.1 - 2.7 7.3 16.4 3.1 7.0 16.4 1.1 1 0 0 1 1 1 0 FAM76 protein PNISR PF15996.5 EGF97683.1 - 7.5 6.8 17.1 8.8 6.5 17.1 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF3195 PF11424.8 EGF97685.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGF97685.1 - 0.12 11.3 0.2 0.14 11.1 0.2 1.1 1 0 0 1 1 1 0 NUC194 domain DUF2457 PF10446.9 EGF97688.1 - 0.21 10.7 9.6 0.23 10.6 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 EGF97688.1 - 6.9 5.9 12.7 9.5 5.4 12.7 1.2 1 0 0 1 1 1 0 NOA36 protein zf-RING_2 PF13639.6 EGF97690.1 - 2.3e-06 27.8 1.2 3.7e-06 27.2 1.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF97690.1 - 0.00022 21.0 0.7 0.00039 20.2 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGF97690.1 - 0.0022 17.7 1.3 0.0027 17.4 0.1 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf_C2H2_10 PF18414.1 EGF97690.1 - 0.014 14.9 0.4 0.029 13.9 0.4 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger zf-rbx1 PF12678.7 EGF97690.1 - 0.059 13.7 5.1 0.32 11.3 5.1 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Med7 PF05983.11 EGF97691.1 - 2.6e-12 47.2 0.7 2.4e-11 44.1 0.7 2.0 1 1 0 1 1 1 1 MED7 protein zf-C3HC4_5 PF17121.5 EGF97691.1 - 0.00029 20.7 1.3 0.0011 18.8 0.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF1116 PF06545.11 EGF97691.1 - 0.2 11.1 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) Baculo_PEP_C PF04513.12 EGF97692.1 - 0.0044 17.1 0.3 0.0073 16.4 0.3 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EGF97692.1 - 0.028 13.3 5.6 0.038 12.9 5.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein COG5 PF10392.9 EGF97692.1 - 0.058 13.6 1.3 0.087 13.0 1.3 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 MbeD_MobD PF04899.12 EGF97692.1 - 0.081 13.1 0.7 0.26 11.4 0.7 1.9 1 1 0 1 1 1 0 MbeD/MobD like DUF948 PF06103.11 EGF97692.1 - 0.093 13.0 0.9 0.19 12.0 0.9 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2730 PF10805.8 EGF97692.1 - 0.11 12.6 2.2 0.18 11.9 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) XkdW PF09636.10 EGF97692.1 - 0.34 11.0 1.7 0.56 10.3 1.4 1.5 1 1 0 1 1 1 0 XkdW protein FlaC_arch PF05377.11 EGF97692.1 - 1.8 9.0 7.5 5.6 7.4 2.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 EGF97692.1 - 1.8 8.7 5.6 9.4 6.4 3.4 2.3 1 1 1 2 2 2 0 bZIP transcription factor LPP PF04728.13 EGF97692.1 - 2.4 8.6 4.5 1.6 9.2 0.4 2.4 1 1 1 2 2 2 0 Lipoprotein leucine-zipper zf-RING_UBOX PF13445.6 EGF97698.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 RING-type zinc-finger DUF4354 PF14263.6 EGF97698.1 - 0.09 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) DUF4354 PF14263.6 EGF97699.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) DUF3195 PF11424.8 EGF97702.1 - 0.1 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGF97702.1 - 0.15 11.0 0.4 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 NUC194 domain DUF2170 PF09938.9 EGF97702.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) SRI PF08236.11 EGF97707.1 - 0.23 11.6 1.5 0.39 10.9 1.5 1.3 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain ABC2_membrane PF01061.24 EGF97712.1 - 8.7e-23 80.8 11.5 1.4e-22 80.1 11.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter GP4 PF03010.14 EGF97712.1 - 0.042 13.8 0.2 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 GP4 SNF2_N PF00176.23 EGF97713.1 - 4.6e-52 176.9 3.4 3.4e-30 104.9 0.3 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 EGF97713.1 - 0.00037 20.5 0.7 0.28 11.2 0.0 2.6 2 1 1 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EGF97713.1 - 0.05 13.4 0.1 8.3 6.1 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGF97713.1 - 0.056 13.1 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase S8_pro-domain PF16470.5 EGF97713.1 - 0.093 13.5 0.1 0.51 11.2 0.0 2.2 1 1 1 2 2 2 0 Peptidase S8 pro-domain DUF3247 PF11607.8 EGF97717.1 - 0.093 13.0 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) Pkinase PF00069.25 EGF97718.1 - 3.7e-62 210.1 0.0 4.4e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF97718.1 - 1.5e-43 148.9 0.0 1.9e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF97718.1 - 0.0001 21.8 0.1 0.00029 20.3 0.1 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGF97718.1 - 0.0021 16.9 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGF97718.1 - 0.0047 16.3 0.2 0.0081 15.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGF97718.1 - 0.031 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 EGF97718.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ATG2_CAD PF13329.6 EGF97720.1 - 0.09 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif Macoilin PF09726.9 EGF97721.1 - 0.31 9.5 26.6 0.36 9.3 26.6 1.1 1 0 0 1 1 1 0 Macoilin family Egh16-like PF11327.8 EGF97723.1 - 6.3e-26 91.9 1.9 6.3e-26 91.9 1.9 1.4 2 0 0 2 2 2 1 Egh16-like virulence factor RF-1 PF00472.20 EGF97723.1 - 0.09 12.7 0.6 0.16 11.9 0.6 1.3 1 0 0 1 1 1 0 RF-1 domain POTRA_2 PF08479.11 EGF97723.1 - 0.17 11.7 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 POTRA domain, ShlB-type CxC1 PF18802.1 EGF97727.1 - 5.3e-13 49.0 0.1 5.2e-12 45.8 0.1 2.3 1 1 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF97727.1 - 4.2e-05 23.7 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF1249 PF06853.12 EGF97727.1 - 0.028 14.4 2.3 0.41 10.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1249) zf-CCHC PF00098.23 EGF97728.1 - 2.5e-07 30.4 10.4 1.7e-05 24.7 2.6 2.4 2 0 0 2 2 2 2 Zinc knuckle Retrotran_gag_2 PF14223.6 EGF97728.1 - 0.0012 18.5 0.1 0.0025 17.5 0.1 1.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 EGF97728.1 - 0.0092 15.7 4.4 0.77 9.5 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EGF97728.1 - 1.6 8.6 12.7 3 7.8 2.1 2.4 2 0 0 2 2 2 0 Zinc knuckle APS_kinase PF01583.20 EGF97729.1 - 1.4e-66 223.3 0.0 1.7e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 EGF97729.1 - 8.3e-07 29.6 0.1 1.3e-06 29.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGF97729.1 - 1.2e-06 28.7 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EGF97729.1 - 5.4e-05 23.2 0.0 7.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 EGF97729.1 - 7.6e-05 22.3 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 SRP54 PF00448.22 EGF97729.1 - 0.00077 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PRK PF00485.18 EGF97729.1 - 0.0039 17.0 0.0 0.0081 15.9 0.0 1.5 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EGF97729.1 - 0.0053 17.1 0.1 0.01 16.2 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EGF97729.1 - 0.0085 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 EGF97729.1 - 0.0089 15.8 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain PEPCK_ATP PF01293.20 EGF97729.1 - 0.0097 14.6 0.1 0.012 14.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase SWI2_SNF2 PF18766.1 EGF97729.1 - 0.016 14.9 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_31 PF13614.6 EGF97729.1 - 0.018 14.9 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGF97729.1 - 0.02 15.3 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EGF97729.1 - 0.03 14.8 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 EGF97729.1 - 0.041 12.9 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EGF97729.1 - 0.054 13.4 0.6 0.39 10.6 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EGF97729.1 - 0.055 13.2 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EGF97729.1 - 0.099 12.7 0.8 3.8 7.5 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain CLP1_P PF16575.5 EGF97729.1 - 0.16 11.8 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF702 PF05142.12 EGF97731.1 - 1.4e-05 25.6 5.3 3.5e-05 24.3 5.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF702) His_Phos_1 PF00300.22 EGF97732.1 - 3.3e-14 53.0 0.1 6.2e-14 52.1 0.1 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Phage_base_V PF04717.12 EGF97732.1 - 0.02 14.8 0.4 0.06 13.3 0.1 1.8 2 0 0 2 2 2 0 Type VI secretion system, phage-baseplate injector STE3 PF02076.15 EGF97739.1 - 1.1e-73 248.0 14.8 1.3e-73 247.8 14.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor Pax7 PF12360.8 EGF97740.1 - 0.011 16.0 1.0 10 6.4 0.0 3.3 1 1 2 3 3 3 0 Paired box protein 7 zf-TRM13_CCCH PF11722.8 EGF97740.1 - 0.044 13.6 0.3 45 3.9 0.0 3.0 3 0 0 3 3 3 0 CCCH zinc finger in TRM13 protein YpM PF09144.10 EGF97740.1 - 0.26 11.5 3.1 0.75 10.0 1.0 1.9 1 1 2 3 3 3 0 Yersinia pseudo-tuberculosis mitogen Neurokinin_B PF03823.14 EGF97740.1 - 5.5 7.1 4.9 26 5.0 0.5 2.3 1 1 1 2 2 2 0 Neurokinin B KxDL PF10241.9 EGF97741.1 - 0.036 14.3 0.8 2.4 8.5 0.0 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein Spc7 PF08317.11 EGF97741.1 - 0.13 11.1 2.9 0.24 10.2 2.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 EGF97741.1 - 0.36 11.4 4.2 1.7 9.2 4.2 2.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF948 PF06103.11 EGF97741.1 - 0.45 10.8 2.6 1.1 9.6 1.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-C4H2 PF10146.9 EGF97741.1 - 0.86 9.9 16.1 1.9 8.7 15.9 1.7 2 1 0 2 2 2 0 Zinc finger-containing protein UPF0242 PF06785.11 EGF97741.1 - 2.8 8.0 6.4 5.3 7.1 6.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HMMR_N PF15905.5 EGF97741.1 - 7.7 5.9 16.3 0.086 12.3 5.3 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal hNIFK_binding PF12196.8 EGF97742.1 - 0.74 9.4 3.5 8.6 5.9 0.1 2.9 2 1 0 2 2 2 0 FHA Ki67 binding domain of hNIFK FAR1 PF03101.15 EGF97745.1 - 0.005 17.5 0.0 0.0085 16.8 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain FAR1 PF03101.15 EGF97746.1 - 0.00053 20.6 0.2 0.0013 19.4 0.2 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 EGF97746.1 - 0.00056 20.3 0.3 0.00056 20.3 0.3 2.6 3 1 0 3 3 3 1 Transcription factor AFT MitMem_reg PF13012.6 EGF97746.1 - 3.2 8.2 7.3 7.8 7.0 1.8 3.2 2 2 0 2 2 2 0 Maintenance of mitochondrial structure and function ABC_tran_CTD PF16326.5 EGF97747.1 - 0.054 13.7 0.6 0.59 10.4 0.1 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain HTH_33 PF13592.6 EGF97748.1 - 6.8e-06 25.6 0.0 0.0073 15.9 0.0 2.3 2 0 0 2 2 2 2 Winged helix-turn helix HTH_28 PF13518.6 EGF97748.1 - 0.00035 20.6 0.0 0.00066 19.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain SelB-wing_3 PF09107.11 EGF97748.1 - 0.0032 17.1 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor SelB, winged helix HTH_23 PF13384.6 EGF97748.1 - 0.032 14.0 0.4 0.1 12.4 0.1 2.1 2 1 0 2 2 2 0 Homeodomain-like domain HTH_32 PF13565.6 EGF97748.1 - 0.072 13.7 0.2 2 9.1 0.1 2.2 1 1 1 2 2 2 0 Homeodomain-like domain Phage_BR0599 PF09356.10 EGF97748.1 - 0.11 12.9 0.1 0.3 11.5 0.0 1.7 2 0 0 2 2 2 0 Phage conserved hypothetical protein BR0599 HTH_29 PF13551.6 EGF97748.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix SNN_linker PF09050.10 EGF97749.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Stannin unstructured linker HgmA PF04209.13 EGF97752.1 - 0.07 11.8 0.2 0.082 11.6 0.2 1.0 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase NPV_P10 PF05531.12 EGF97753.1 - 0.045 14.2 1.2 0.14 12.6 1.2 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Fzo_mitofusin PF04799.13 EGF97753.1 - 0.29 10.7 4.8 1.2 8.6 0.3 2.5 2 0 0 2 2 2 0 fzo-like conserved region CLN3 PF02487.17 EGF97753.1 - 0.4 9.7 0.8 0.71 8.9 0.8 1.3 1 0 0 1 1 1 0 CLN3 protein DUF4337 PF14235.6 EGF97753.1 - 0.45 10.6 2.6 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Tropomyosin_1 PF12718.7 EGF97754.1 - 0.00037 20.7 0.2 0.00073 19.7 0.2 1.5 1 0 0 1 1 1 1 Tropomyosin like DUF5035 PF16438.5 EGF97754.1 - 0.039 13.8 0.2 0.067 13.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5035) Med4 PF10018.9 EGF97754.1 - 0.36 10.5 2.4 3.1 7.4 0.2 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 LUC7 PF03194.15 EGF97754.1 - 1.2 8.7 6.3 2.2 7.9 6.1 1.5 1 1 0 1 1 1 0 LUC7 N_terminus PBP1_TM PF14812.6 EGF97755.1 - 5.3 7.5 15.9 3.1 8.3 3.9 2.7 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 EGF97755.1 - 5.4 7.3 9.8 0.91 9.8 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Mtc PF03820.17 EGF97756.1 - 3.2e-116 387.7 0.0 3.6e-116 387.6 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier NAM-associated PF14303.6 EGF97757.1 - 1.2e-12 48.9 0.3 1.2e-12 48.9 0.3 1.4 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain CtaG_Cox11 PF04442.14 EGF97758.1 - 3.7e-58 195.8 0.0 5.2e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF2310 PF10071.9 EGF97758.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) NUDIX PF00293.28 EGF97759.1 - 6.2e-08 32.7 0.0 8.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Pectate_lyase22 PF14583.6 EGF97759.1 - 0.056 12.1 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 Oligogalacturonate lyase HTH_57 PF18679.1 EGF97763.1 - 0.085 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 ThcOx helix turn helix domain SMC_N PF02463.19 EGF97764.1 - 3.6e-61 206.4 0.0 6e-61 205.7 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGF97764.1 - 4.5e-28 97.9 0.3 1.4e-27 96.3 0.0 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGF97764.1 - 2.8e-13 50.4 0.3 7.1e-06 26.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGF97764.1 - 2.3e-08 33.6 0.0 7.2e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EGF97764.1 - 3e-07 31.1 12.1 3e-07 31.1 12.1 6.7 2 2 2 4 4 4 1 AAA domain Seryl_tRNA_N PF02403.22 EGF97764.1 - 0.003 17.8 1.6 0.003 17.8 1.6 9.7 5 4 4 10 10 10 2 Seryl-tRNA synthetase N-terminal domain SbcCD_C PF13558.6 EGF97764.1 - 0.0043 17.3 0.1 0.019 15.2 0.0 2.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 EGF97764.1 - 0.078 12.6 0.0 0.078 12.6 0.0 5.5 6 0 0 6 6 6 0 AAA domain ABC_tran PF00005.27 EGF97764.1 - 0.27 11.8 0.0 0.27 11.8 0.0 6.5 4 3 0 4 4 4 0 ABC transporter AAA_22 PF13401.6 EGF97764.1 - 0.59 10.4 5.0 8.7 6.6 0.0 4.3 3 1 0 3 3 3 0 AAA domain Zn_Tnp_IS1595 PF12760.7 EGF97765.1 - 0.77 9.8 11.8 0.82 9.7 8.3 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain B-block_TFIIIC PF04182.12 EGF97766.1 - 0.0074 16.4 0.0 17 5.6 0.0 3.5 4 0 0 4 4 4 2 B-block binding subunit of TFIIIC His_Phos_2 PF00328.22 EGF97768.1 - 8.2e-48 163.7 0.0 1e-47 163.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) EzrA PF06160.12 EGF97770.1 - 0.0031 15.8 0.2 0.0044 15.3 0.2 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA BLOC1_2 PF10046.9 EGF97770.1 - 0.004 17.4 1.5 0.28 11.5 0.2 2.3 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec5 PF15469.6 EGF97770.1 - 0.015 15.1 0.7 0.023 14.5 0.7 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 Allexi_40kDa PF05549.11 EGF97770.1 - 0.034 13.7 1.1 0.055 13.0 1.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein NPV_P10 PF05531.12 EGF97770.1 - 0.04 14.4 2.8 0.26 11.8 1.6 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Apo-VLDL-II PF05418.11 EGF97770.1 - 0.043 14.4 0.2 0.084 13.5 0.2 1.4 1 0 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) DUF1664 PF07889.12 EGF97770.1 - 0.086 12.9 1.0 0.15 12.1 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LPP PF04728.13 EGF97770.1 - 0.14 12.5 6.0 7.7 7.0 0.6 3.1 1 1 2 3 3 3 0 Lipoprotein leucine-zipper Sec34 PF04136.15 EGF97770.1 - 0.17 11.8 0.9 0.27 11.1 0.9 1.3 1 0 0 1 1 1 0 Sec34-like family Vps5 PF09325.10 EGF97770.1 - 0.22 11.0 2.3 0.31 10.5 2.3 1.1 1 0 0 1 1 1 0 Vps5 C terminal like MbeD_MobD PF04899.12 EGF97770.1 - 0.26 11.5 1.8 23 5.2 0.1 2.9 2 1 1 3 3 3 0 MbeD/MobD like PIRT PF15099.6 EGF97771.1 - 0.14 11.7 1.6 2.2 7.9 0.0 2.2 1 1 0 2 2 2 0 Phosphoinositide-interacting protein family SelP_N PF04592.14 EGF97772.1 - 0.14 11.5 20.6 0.16 11.4 20.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PLRV_ORF5 PF01690.17 EGF97773.1 - 0.03 13.1 0.2 0.034 12.9 0.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Pkinase PF00069.25 EGF97775.1 - 1.8e-65 221.0 0.0 2.5e-65 220.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF97775.1 - 4.5e-37 127.7 0.0 1.3e-36 126.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF97775.1 - 7e-05 22.3 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGF97775.1 - 0.00017 20.5 0.3 0.00055 18.8 0.3 1.8 1 1 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGF97775.1 - 0.024 13.7 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EGF97775.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGF97775.1 - 0.2 11.3 0.0 0.55 9.8 0.0 1.7 1 1 0 1 1 1 0 RIO1 family Ufd2P_core PF10408.9 EGF97776.1 - 2.5e-198 660.6 7.3 3.4e-198 660.2 7.3 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EGF97776.1 - 7.7e-29 99.7 3.5 7.9e-29 99.6 1.3 2.3 2 0 0 2 2 2 1 U-box domain PPI_Ypi1 PF07491.11 EGF97777.1 - 1.3e-23 82.6 0.5 1.3e-23 82.6 0.5 2.0 2 0 0 2 2 2 1 Protein phosphatase inhibitor Helitron_like_N PF14214.6 EGF97781.1 - 0.022 15.0 0.7 0.039 14.2 0.3 1.6 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus Sec2p PF06428.11 EGF97783.1 - 0.16 11.9 0.4 0.29 11.1 0.4 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p GAS PF13851.6 EGF97785.1 - 0.0059 16.0 11.0 0.0059 16.0 11.0 4.7 3 2 2 5 5 5 2 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 EGF97785.1 - 0.0086 16.6 15.6 0.0086 16.6 15.6 5.1 3 2 1 4 4 4 1 Apg6 coiled-coil region DUF3677 PF12432.8 EGF97785.1 - 1.1 9.7 5.6 3.8 7.9 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) Melibiase_2 PF16499.5 EGF97786.1 - 1.4e-19 70.4 0.6 5.2e-11 42.2 0.0 2.8 2 1 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 EGF97786.1 - 1.2e-10 41.3 0.0 2.9e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EGF97786.1 - 0.0048 15.9 0.0 0.01 14.8 0.0 1.6 1 1 0 1 1 1 1 Melibiase Peptidase_C27 PF05407.12 EGF97786.1 - 0.3 11.1 2.8 0.71 9.9 2.8 1.6 1 0 0 1 1 1 0 Rubella virus endopeptidase CorA PF01544.18 EGF97787.1 - 2.1e-41 142.2 0.0 2.5e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 EGF97787.1 - 0.0061 16.6 1.0 0.012 15.7 0.3 1.8 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus RasGAP PF00616.19 EGF97788.1 - 1.4 8.6 5.9 2.2 7.9 0.3 3.1 3 0 0 3 3 3 0 GTPase-activator protein for Ras-like GTPase Aminotran_4 PF01063.19 EGF97789.1 - 1.6e-28 100.1 0.0 2.1e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV bVLRF1 PF18826.1 EGF97791.1 - 9.8e-10 38.5 0.0 1.4e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Tom22 PF04281.13 EGF97791.1 - 0.048 13.4 0.1 0.077 12.8 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF365 PF04033.12 EGF97791.1 - 0.062 13.6 0.2 0.11 12.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF365) bVLRF1 PF18826.1 EGF97792.1 - 1.1e-09 38.3 0.1 2.4e-09 37.2 0.0 1.5 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor HrcA PF01628.21 EGF97793.1 - 0.017 15.1 0.1 0.036 14.0 0.1 1.6 1 0 0 1 1 1 0 HrcA protein C terminal domain LTV PF04180.14 EGF97795.1 - 0.35 10.6 2.9 0.56 9.9 2.9 1.3 1 0 0 1 1 1 0 Low temperature viability protein CxC1 PF18802.1 EGF97796.1 - 8e-10 38.8 3.8 3.4e-08 33.6 0.1 2.4 1 1 1 2 2 2 2 CxC1 like cysteine cluster associated with KDZ transposases DnaJ PF00226.31 EGF97798.1 - 1.3e-05 25.2 0.1 3.4e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 DnaJ domain BNIP3 PF06553.12 EGF97798.1 - 0.08 12.6 0.0 0.08 12.6 0.0 1.6 2 0 0 2 2 2 0 BNIP3 HAD_2 PF13419.6 EGF97799.1 - 5.7e-06 26.5 0.1 2.5e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGF97799.1 - 0.0018 18.6 0.0 0.0034 17.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGF97799.1 - 0.016 15.2 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 HAD-hyrolase-like FAD_binding_4 PF01565.23 EGF97800.1 - 6.2e-22 77.8 0.9 1.1e-21 77.1 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGF97800.1 - 3.8e-08 33.3 0.1 7.5e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like 3Beta_HSD PF01073.19 EGF97801.1 - 5.2e-13 48.6 0.0 1e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGF97801.1 - 2.9e-08 33.2 0.0 1.3e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGF97801.1 - 2.3e-07 30.5 0.5 1.4e-06 28.0 0.5 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGF97801.1 - 5.2e-07 29.7 0.1 1.9e-06 27.9 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGF97801.1 - 0.00011 21.7 0.1 0.00035 20.1 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGF97801.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_S5 PF00333.20 EGF97802.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Ribonucleas_3_3 PF14622.6 EGF97802.1 - 0.049 13.8 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 Ribonuclease-III-like dsrm PF00035.26 EGF97802.1 - 0.14 12.9 0.0 0.22 12.3 0.0 1.3 1 0 0 1 1 1 0 Double-stranded RNA binding motif GPI-anchored PF10342.9 EGF97804.1 - 0.0098 16.6 0.0 0.031 15.0 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ADH_N PF08240.12 EGF97805.1 - 6.1e-24 84.0 2.4 1.1e-23 83.1 0.3 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGF97805.1 - 6.9e-21 74.6 0.0 1.3e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGF97805.1 - 3.5e-08 33.2 0.2 5.8e-08 32.5 0.2 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGF97805.1 - 0.0014 19.7 0.0 0.0024 18.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGF97805.1 - 0.0023 17.3 0.2 0.0038 16.6 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_11 PF08241.12 EGF97805.1 - 0.14 12.8 0.0 0.37 11.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 EGF97805.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain P2X_receptor PF00864.19 EGF97805.1 - 0.19 10.7 0.4 0.3 10.1 0.4 1.2 1 0 0 1 1 1 0 ATP P2X receptor ADH_N PF08240.12 EGF97809.1 - 2.1e-23 82.3 1.5 2.2e-23 82.2 0.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGF97809.1 - 3.7e-20 72.2 0.0 8.2e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGF97809.1 - 3.3e-07 30.0 0.2 5.8e-07 29.2 0.2 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGF97809.1 - 0.00035 21.6 0.0 0.0006 20.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGF97809.1 - 0.00059 19.2 0.1 0.00089 18.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EGF97809.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DDE_3 PF13358.6 EGF97810.1 - 1.6e-12 47.4 0.0 1.8e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Retrotran_gag_2 PF14223.6 EGF97811.1 - 0.0023 17.6 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 EGF97811.1 - 0.025 14.7 1.4 0.033 14.3 0.2 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 EGF97811.1 - 0.027 14.3 0.6 0.072 12.9 0.6 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF4219 PF13961.6 EGF97811.1 - 0.12 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Glycos_transf_2 PF00535.26 EGF97812.1 - 0.00071 19.4 3.9 0.11 12.3 0.7 2.5 1 1 1 2 2 2 2 Glycosyl transferase family 2 MIP PF00230.20 EGF97813.1 - 2.4e-13 50.3 5.4 3.4e-13 49.8 5.4 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF5381 PF17353.2 EGF97813.1 - 2.3 7.9 4.0 1.4 8.6 1.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5381) FeoB_C PF07664.12 EGF97813.1 - 6.8 6.5 9.8 8.6 6.1 1.7 3.4 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus 3Beta_HSD PF01073.19 EGF97814.1 - 4e-15 55.6 0.0 7.9e-15 54.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGF97814.1 - 2.1e-12 46.8 0.0 8e-12 44.9 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGF97814.1 - 3.8e-11 42.9 0.0 6.9e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGF97814.1 - 2e-07 30.8 0.0 5.4e-07 29.3 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGF97814.1 - 4.8e-07 29.8 0.0 1.9e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGF97814.1 - 0.0023 17.1 0.0 0.0041 16.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MTBP_N PF14918.6 EGF97814.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 MDM2-binding adh_short PF00106.25 EGF97814.1 - 0.035 13.6 0.1 0.29 10.5 0.0 2.3 2 1 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 EGF97814.1 - 0.065 12.3 0.0 0.25 10.4 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain PqqD PF05402.12 EGF97814.1 - 0.12 12.6 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Neisseria_TspB PF05616.13 EGF97815.1 - 0.16 10.4 0.1 0.16 10.4 0.1 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Zot PF05707.12 EGF97816.1 - 0.00025 20.7 0.0 0.00042 20.0 0.0 1.4 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) DUF853 PF05872.12 EGF97816.1 - 0.0014 17.3 0.0 0.0019 16.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) CPT PF07931.12 EGF97816.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DnaJ PF00226.31 EGF97817.1 - 6.9e-20 70.9 1.7 6.9e-20 70.9 1.7 2.4 3 0 0 3 3 3 1 DnaJ domain Abhydrolase_2 PF02230.16 EGF97818.1 - 1.4e-17 64.2 0.1 6.9e-17 62.0 0.1 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGF97818.1 - 0.00058 20.5 0.0 0.00089 19.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGF97818.1 - 0.025 14.3 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) RE_MjaI PF09568.10 EGF97818.1 - 0.25 11.2 1.5 1.3 8.8 0.3 2.1 2 0 0 2 2 2 0 MjaI restriction endonuclease DEAD PF00270.29 EGF97819.1 - 2.6e-44 151.1 0.0 6.5e-44 149.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF97819.1 - 8.4e-27 93.7 0.0 5.1e-26 91.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF97819.1 - 7e-06 26.2 0.3 1.9e-05 24.7 0.0 1.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGF97819.1 - 0.023 13.9 1.2 0.025 13.8 0.0 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase PBP_sp32 PF07222.12 EGF97819.1 - 1.3 8.4 3.3 2.1 7.7 3.3 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 zf-CCHC PF00098.23 EGF97819.1 - 4.3 7.6 7.8 0.14 12.3 1.8 1.8 2 0 0 2 2 2 0 Zinc knuckle UQ_con PF00179.26 EGF97820.1 - 7.9e-48 161.7 0.3 8.9e-48 161.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGF97820.1 - 0.0079 15.9 0.0 0.0097 15.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGF97820.1 - 0.11 12.8 1.5 0.19 12.0 1.4 1.5 1 1 0 1 1 1 0 RWD domain TPR_2 PF07719.17 EGF97822.1 - 2.2e-25 86.6 13.2 0.0021 18.0 0.6 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF97822.1 - 2.3e-24 85.4 10.3 1.3e-10 41.3 0.0 7.0 6 1 1 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EGF97822.1 - 6.2e-17 60.6 6.9 0.0046 16.7 0.5 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGF97822.1 - 3.2e-16 59.4 12.3 1.1e-06 28.8 0.1 7.4 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGF97822.1 - 1.8e-12 46.4 5.6 0.0093 16.1 0.2 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGF97822.1 - 1.8e-09 37.9 3.7 0.63 10.6 0.0 6.4 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGF97822.1 - 1.2e-07 31.6 0.9 36 5.1 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGF97822.1 - 1.4e-07 31.7 15.3 0.34 11.8 0.0 9.2 7 3 2 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGF97822.1 - 1.1e-06 28.9 15.3 5.7 7.8 0.6 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGF97822.1 - 2e-06 28.3 18.8 0.042 14.5 2.1 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGF97822.1 - 5e-06 26.2 9.2 3.2 8.0 0.0 7.3 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF97822.1 - 5.5e-05 22.8 8.9 0.47 10.2 0.1 6.0 6 1 1 7 7 7 2 TPR repeat TPR_10 PF13374.6 EGF97822.1 - 0.00032 20.5 9.0 1.5 8.8 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGF97822.1 - 0.028 14.5 0.3 0.028 14.5 0.3 5.0 7 0 0 7 7 5 0 Tetratricopeptide repeat aGPT-Pplase2 PF18724.1 EGF97822.1 - 0.073 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 BTAD PF03704.17 EGF97822.1 - 0.24 11.8 1.6 2 8.8 1.0 2.6 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 EGF97822.1 - 1.1 10.1 7.0 42 5.2 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat FliP PF00813.20 EGF97824.1 - 0.0074 16.2 0.6 0.015 15.2 0.6 1.5 1 0 0 1 1 1 1 FliP family DUF1980 PF09323.10 EGF97826.1 - 0.038 13.9 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DHquinase_I PF01487.15 EGF97827.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Type I 3-dehydroquinase FAR1 PF03101.15 EGF97828.1 - 0.0082 16.8 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain YueH PF14166.6 EGF97829.1 - 0.042 13.7 0.1 0.091 12.6 0.1 1.6 1 0 0 1 1 1 0 YueH-like protein WXG100 PF06013.12 EGF97831.1 - 0.00032 20.9 0.1 22 5.4 0.0 4.0 2 1 2 4 4 4 1 Proteins of 100 residues with WXG DUF1964 PF09244.10 EGF97831.1 - 0.015 15.7 0.1 85 3.7 0.0 4.1 2 1 2 4 4 4 0 Domain of unknown function (DUF1964) Antimicrobial_6 PF08036.11 EGF97831.1 - 0.019 15.0 0.0 1.6e+02 2.4 0.0 3.9 4 0 0 4 4 4 0 Diapausin family of antimicrobial peptide CxC1 PF18802.1 EGF97832.1 - 4.5e-22 78.2 1.7 3.8e-17 62.3 0.2 2.3 1 1 1 2 2 2 2 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF97832.1 - 2.1e-06 27.8 0.3 4.7e-06 26.7 0.1 1.6 1 1 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGF97832.1 - 0.0024 17.7 0.2 0.0034 17.2 0.2 1.3 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases SCP2_2 PF13530.6 EGF97834.1 - 0.076 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Sterol carrier protein domain Zip PF02535.22 EGF97834.1 - 0.39 9.9 2.3 1.6 7.9 2.8 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter Serinc PF03348.15 EGF97834.1 - 0.4 9.5 1.2 0.49 9.3 1.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 EGF97834.1 - 2.6 6.7 6.2 3 6.5 6.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 EGF97834.1 - 2.9 6.6 7.7 3.4 6.4 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) BORG_CEP PF14957.6 EGF97834.1 - 4.7 8.4 13.3 2 9.6 10.2 1.9 1 1 1 2 2 2 0 Cdc42 effector NPR3 PF03666.13 EGF97834.1 - 5.6 5.6 10.3 7.5 5.2 10.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 EGF97837.1 - 1 7.5 15.0 0.1 10.8 8.7 1.9 2 0 0 2 2 2 0 Nop14-like family LRR_6 PF13516.6 EGF97839.1 - 7.6e-14 50.5 25.5 0.0061 16.5 0.4 10.1 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.7 EGF97839.1 - 1.8e-06 28.2 20.4 0.0032 17.8 1.4 6.9 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF97839.1 - 0.003 17.3 24.4 0.22 11.3 0.5 6.8 4 3 1 5 5 5 2 Leucine rich repeat Phage_head_fibr PF11133.8 EGF97839.1 - 0.05 13.0 0.2 0.088 12.2 0.2 1.3 1 0 0 1 1 1 0 Head fiber protein LRR_1 PF00560.33 EGF97839.1 - 0.13 12.9 16.7 1.2e+02 3.9 0.0 8.9 9 0 0 9 9 9 0 Leucine Rich Repeat RdRP PF05183.12 EGF97840.1 - 7.7e-171 569.7 0.0 9.6e-171 569.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Hexokinase_2 PF03727.16 EGF97841.1 - 2.1e-83 279.5 0.0 2.8e-83 279.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGF97841.1 - 4.2e-69 232.4 0.0 6.5e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DUF1802 PF08819.11 EGF97843.1 - 0.034 14.0 0.1 0.042 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1802) DEAD PF00270.29 EGF97845.1 - 1.2e-45 155.4 0.1 1.9e-45 154.8 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF97845.1 - 1.4e-24 86.6 0.0 1.8e-23 83.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGF97845.1 - 1.9e-16 60.0 0.1 3.7e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGF97845.1 - 0.00045 20.3 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CLTH PF10607.9 EGF97846.1 - 1.9e-30 105.7 0.0 2.6e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGF97846.1 - 3.5e-10 39.5 0.0 6.7e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 LisH Cyclin_N PF00134.23 EGF97847.1 - 0.058 13.1 1.3 0.29 10.9 0.9 2.1 1 1 1 2 2 2 0 Cyclin, N-terminal domain Cyt-b5 PF00173.28 EGF97850.1 - 0.0025 17.9 0.0 0.0045 17.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1002 PF06207.11 EGF97850.1 - 0.15 11.5 1.3 0.26 10.8 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) EVI2A PF05399.11 EGF97851.1 - 0.84 9.2 4.6 1.2 8.7 4.6 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) PRCC PF10253.9 EGF97852.1 - 1.1 10.0 8.5 0.17 12.7 4.4 1.6 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DnaJ PF00226.31 EGF97854.1 - 1.2e-14 54.2 0.1 2.3e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Rit1_C PF17184.4 EGF97856.1 - 4.5e-97 324.7 0.1 6.2e-97 324.3 0.1 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EGF97856.1 - 2.4e-27 95.4 0.7 1e-26 93.4 0.2 2.2 1 1 1 2 2 2 1 Rit1 DUSP-like domain Integrase_H2C2 PF17921.1 EGF97858.1 - 6.5e-05 22.9 0.5 0.00014 21.9 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF3818 PF12825.7 EGF97860.1 - 1.6e-129 431.8 0.0 2.1e-129 431.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EGF97860.1 - 1.1e-39 135.4 1.9 2.5e-39 134.2 1.9 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EGF97860.1 - 6.6e-09 35.7 0.1 3.2e-08 33.6 0.0 2.3 2 1 0 2 2 2 1 PX domain UPF0122 PF04297.14 EGF97862.1 - 0.0078 16.4 0.1 0.013 15.8 0.1 1.3 1 1 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4_2 PF08281.12 EGF97862.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 RVT_3 PF13456.6 EGF97866.1 - 8.8e-07 28.8 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Ras PF00071.22 EGF97868.1 - 5.8e-43 146.3 0.0 7.8e-43 145.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF97868.1 - 8.7e-28 97.0 0.0 1.2e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF97868.1 - 2.2e-10 40.3 0.0 7.5e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF97868.1 - 7.3e-05 22.4 0.0 0.00029 20.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EGF97868.1 - 0.00061 20.1 0.0 0.00096 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF97868.1 - 0.00078 19.9 0.1 0.0049 17.3 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 EGF97868.1 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGF97868.1 - 0.0063 16.4 0.0 0.34 10.8 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EGF97868.1 - 0.0066 16.5 0.0 0.016 15.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EGF97868.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGF97868.1 - 0.062 13.8 0.3 0.11 13.0 0.0 1.7 2 1 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 EGF97868.1 - 0.064 12.8 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 EGF97868.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 EGF97868.1 - 0.34 10.7 1.9 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Nmad3 PF18754.1 EGF97873.1 - 0.091 12.3 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 TBP PF00352.21 EGF97874.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3251 PF11622.8 EGF97876.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Abhydrolase_1 PF00561.20 EGF97882.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_C65 PF10275.9 EGF97883.1 - 0.0005 19.6 0.0 0.00092 18.7 0.0 1.5 2 0 0 2 2 2 1 Peptidase C65 Otubain Enkurin PF13864.6 EGF97887.1 - 5 7.6 7.3 24 5.5 4.6 2.3 2 0 0 2 2 2 0 Calmodulin-binding SNF2_N PF00176.23 EGF97890.1 - 1.7e-37 129.0 3.3 3.5e-37 127.9 0.7 2.3 2 1 1 3 3 3 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 EGF97890.1 - 0.002 17.9 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ResIII PF04851.15 EGF97890.1 - 0.0083 16.1 0.0 0.018 15.1 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGF97890.1 - 0.044 13.5 0.2 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase Lectin_N PF03954.14 EGF97891.1 - 0.23 11.2 5.6 0.63 9.8 1.2 2.4 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Syntaxin-6_N PF09177.11 EGF97891.1 - 6 7.5 8.8 3.4 8.3 0.8 3.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Syntaxin-6_N PF09177.11 EGF97892.1 - 0.00013 22.5 9.6 0.009 16.5 5.2 2.4 1 1 1 2 2 2 2 Syntaxin 6, N-terminal Lebercilin PF15619.6 EGF97892.1 - 0.003 17.3 8.5 0.003 17.3 8.5 2.3 2 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF2205 PF10224.9 EGF97892.1 - 0.011 15.7 7.8 0.11 12.5 0.1 3.0 2 1 1 3 3 3 0 Short coiled-coil protein UPF0242 PF06785.11 EGF97892.1 - 0.016 15.4 9.2 0.016 15.4 9.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HMMR_N PF15905.5 EGF97892.1 - 0.017 14.6 10.8 0.02 14.4 10.8 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal BLOC1_2 PF10046.9 EGF97892.1 - 0.026 14.8 14.3 0.15 12.4 0.4 3.5 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EGF97892.1 - 0.035 14.1 7.5 1.1 9.3 2.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DASH_Duo1 PF08651.10 EGF97892.1 - 0.038 13.8 7.4 4.3 7.2 0.2 3.5 2 2 1 3 3 3 0 DASH complex subunit Duo1 DUF3080 PF11279.8 EGF97892.1 - 0.05 12.8 9.4 0.084 12.1 9.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3080) BORCS7 PF16088.5 EGF97892.1 - 0.07 13.4 6.4 0.15 12.3 6.1 1.9 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 Exonuc_VII_L PF02601.15 EGF97892.1 - 0.08 12.5 7.7 0.091 12.3 7.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 EGF97892.1 - 0.086 12.9 6.1 0.68 10.0 3.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 EGF97892.1 - 0.11 13.0 8.4 27 5.3 8.4 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF948 PF06103.11 EGF97892.1 - 0.18 12.1 4.5 1.8 8.8 1.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) BAR_3 PF16746.5 EGF97892.1 - 0.19 11.4 11.7 0.19 11.4 6.6 2.1 1 1 1 2 2 2 0 BAR domain of APPL family Nup54 PF13874.6 EGF97892.1 - 0.22 11.6 6.3 0.56 10.3 2.7 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF713 PF05218.14 EGF97892.1 - 0.26 11.0 7.4 0.56 9.9 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF713) SOGA PF11365.8 EGF97892.1 - 0.36 12.0 10.8 1.1 10.4 4.5 3.1 1 1 2 3 3 3 0 Protein SOGA PRKG1_interact PF15898.5 EGF97892.1 - 0.43 11.5 10.0 2.1 9.3 9.0 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain NPV_P10 PF05531.12 EGF97892.1 - 0.46 11.0 7.0 11 6.5 1.2 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.10 EGF97892.1 - 0.57 10.0 6.6 9.9 6.1 0.5 3.4 3 1 1 4 4 3 0 DASH complex subunit Dam1 DivIVA PF05103.13 EGF97892.1 - 1.4 9.0 9.2 22 5.1 9.1 2.4 1 1 0 1 1 1 0 DivIVA protein Fib_alpha PF08702.10 EGF97892.1 - 1.9 8.6 12.0 3.9 7.7 9.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EMP24_GP25L PF01105.24 EGF97892.1 - 2 8.4 8.9 0.62 10.0 2.4 2.5 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD SlyX PF04102.12 EGF97892.1 - 2 9.1 11.1 15 6.3 0.1 3.2 2 1 0 2 2 2 0 SlyX GrpE PF01025.19 EGF97892.1 - 2.2 7.9 9.8 5.7 6.6 5.2 2.1 1 1 1 2 2 2 0 GrpE XhlA PF10779.9 EGF97892.1 - 2.4 8.4 8.7 7.5 6.8 0.7 3.3 1 1 3 4 4 4 0 Haemolysin XhlA ORF6C PF10552.9 EGF97892.1 - 2.8 8.0 9.6 4.2 7.5 0.6 3.2 1 1 2 3 3 3 0 ORF6C domain FlaC_arch PF05377.11 EGF97892.1 - 4.3 7.8 6.3 7.9 7.0 1.0 3.2 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Prominin PF05478.11 EGF97892.1 - 4.5 5.1 9.9 1.4 6.7 6.3 1.7 1 1 1 2 2 2 0 Prominin bZIP_1 PF00170.21 EGF97892.1 - 5.4 7.2 11.6 14 5.9 0.0 3.8 3 1 0 4 4 4 0 bZIP transcription factor DNA_pol_phi PF04931.13 EGF97895.1 - 0.11 10.6 12.9 0.24 9.5 12.9 1.5 1 0 0 1 1 1 0 DNA polymerase phi Prenyltrans PF00432.21 EGF97899.1 - 2.9e-19 68.5 17.4 1.4e-05 24.7 0.1 6.1 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SNF2_N PF00176.23 EGF97900.1 - 2.4e-41 141.6 4.7 2.6e-41 141.5 4.7 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGF97900.1 - 9.9e-08 32.2 0.1 1.3e-07 31.8 0.1 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGF97900.1 - 2.4e-07 30.7 0.0 2.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGF97900.1 - 0.00043 20.0 0.1 0.00048 19.9 0.1 1.2 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Helicase_C PF00271.31 EGF97901.1 - 9.2e-13 48.5 0.0 1.2e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T3RM_EcoP15I_C PF18273.1 EGF97901.1 - 0.084 13.2 0.0 0.34 11.2 0.0 2.0 1 1 1 2 2 2 0 Type III R-M EcoP15I C-terminal domain Ima1_N PF09779.9 EGF97902.1 - 3.1e-15 57.2 1.5 3.1e-15 57.2 1.5 1.8 2 0 0 2 2 2 1 Ima1 N-terminal domain Epimerase PF01370.21 EGF97903.1 - 5.5e-11 42.4 0.0 8.8e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGF97903.1 - 2.4e-10 40.3 0.0 3.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGF97903.1 - 1.6e-09 37.2 0.0 2.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGF97903.1 - 1.8e-06 27.3 0.0 1e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EGF97903.1 - 4.4e-05 22.8 0.0 7.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGF97903.1 - 6.9e-05 22.8 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGF97903.1 - 8.7e-05 22.2 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EGF97903.1 - 0.0018 17.8 0.0 0.0049 16.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase HEPN_Swt1 PF18731.1 EGF97903.1 - 0.057 13.8 0.5 0.17 12.3 0.5 1.9 1 1 0 1 1 1 0 Swt1-like HEPN polyprenyl_synt PF00348.17 EGF97904.1 - 1.6e-46 158.5 0.0 2e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Epimerase PF01370.21 EGF97907.1 - 3.8e-09 36.4 0.0 8.2e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGF97907.1 - 6.7e-09 35.3 0.0 6.6e-08 32.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EGF97907.1 - 5.1e-06 25.7 0.0 1.1e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGF97907.1 - 7e-05 22.4 0.1 0.0007 19.1 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGF97907.1 - 0.00014 21.8 0.0 0.13 12.1 0.0 2.8 2 1 0 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 EGF97907.1 - 0.0089 15.5 0.0 0.037 13.5 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 EGF97907.1 - 0.014 15.0 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.12 EGF97908.1 - 3.9e-06 26.2 0.0 4.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGF97908.1 - 0.0015 18.0 0.0 0.0032 16.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MARVEL PF01284.23 EGF97909.1 - 9.4e-10 38.7 14.7 1.2e-09 38.3 14.1 1.5 1 1 0 1 1 1 1 Membrane-associating domain TIC20 PF16166.5 EGF97911.1 - 0.069 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Chloroplast import apparatus Tic20-like FXMRP1_C_core PF12235.8 EGF97916.1 - 0.14 12.8 6.0 0.15 12.7 5.6 1.4 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal Strabismus PF06638.11 EGF97916.1 - 0.96 8.0 2.3 1.1 7.8 2.3 1.1 1 0 0 1 1 1 0 Strabismus protein RAP1 PF07218.11 EGF97916.1 - 1 7.5 7.0 1.3 7.3 7.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-C2H2 PF00096.26 EGF97917.1 - 0.016 15.6 3.9 0.072 13.6 0.5 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-TAZ PF02135.16 EGF97917.1 - 0.02 15.4 3.2 0.028 14.9 3.2 1.3 1 0 0 1 1 1 0 TAZ zinc finger zf-C2H2_4 PF13894.6 EGF97917.1 - 0.61 11.1 6.6 0.43 11.5 1.9 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Med7 PF05983.11 EGF97918.1 - 1.8e-14 54.2 0.4 8.7e-10 39.0 0.2 2.1 1 1 1 2 2 2 2 MED7 protein FadA PF09403.10 EGF97919.1 - 0.0094 16.4 0.2 0.015 15.7 0.2 1.4 1 0 0 1 1 1 1 Adhesion protein FadA Glyco_hydro_47 PF01532.20 EGF97922.1 - 1.3e-07 30.9 0.0 1.4e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 NAD_Gly3P_dh_N PF01210.23 EGF97922.1 - 0.19 11.7 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus WD40 PF00400.32 EGF97923.1 - 0.0011 19.8 1.0 3.8 8.5 0.0 3.4 2 1 0 2 2 2 2 WD domain, G-beta repeat Epimerase PF01370.21 EGF97924.1 - 9.4e-06 25.3 0.0 0.00076 19.0 0.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGF97924.1 - 0.00057 19.0 0.0 0.0016 17.5 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGF97924.1 - 0.0017 17.8 0.0 0.14 11.5 0.0 2.4 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGF97924.1 - 0.0032 17.4 0.0 0.78 9.6 0.0 2.3 1 1 1 2 2 2 2 NAD(P)H-binding NAD_binding_4 PF07993.12 EGF97924.1 - 0.0059 15.8 0.0 0.0082 15.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EGF97924.1 - 0.09 12.3 0.0 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family Epimerase PF01370.21 EGF97925.1 - 1.3e-13 51.0 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGF97925.1 - 3.5e-12 45.9 0.0 5.5e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGF97925.1 - 7.9e-10 38.3 0.0 6e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGF97925.1 - 2.6e-08 33.7 0.0 5.4e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGF97925.1 - 4.1e-06 26.8 0.0 7.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGF97925.1 - 1.1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EGF97925.1 - 8.3e-05 22.1 0.0 0.00063 19.3 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGF97925.1 - 0.009 15.9 0.0 0.03 14.3 0.0 1.8 1 1 0 1 1 1 1 KR domain PRO8NT PF08082.11 EGF97926.1 - 1.1e-51 174.8 0.4 1.4e-51 174.5 0.4 1.1 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain PROCN PF08083.11 EGF97926.1 - 0.0029 16.4 0.1 0.005 15.6 0.1 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain Curto_V2 PF07325.11 EGF97927.1 - 2.5 8.0 5.2 4.6 7.1 5.2 1.4 1 0 0 1 1 1 0 Curtovirus V2 protein DUF3835 PF12927.7 EGF97928.1 - 1.2e-05 26.0 0.0 1.2e-05 26.0 0.0 6.5 5 2 1 6 6 6 2 Domain of unknown function (DUF3835) DUF5434 PF17502.2 EGF97928.1 - 0.012 15.6 1.2 0.023 14.7 1.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5434) Malate_DH PF12434.8 EGF97928.1 - 0.063 13.3 0.2 0.48 10.5 0.2 2.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme DUF3438 PF11920.8 EGF97928.1 - 4.3 6.5 5.6 12 5.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3438) E7 PF00527.18 EGF97929.1 - 1.2 9.4 5.3 0.94 9.7 2.5 2.1 2 0 0 2 2 2 0 E7 protein, Early protein Pheromone PF08015.11 EGF97929.1 - 1.5 9.9 18.2 6.6 7.8 8.5 2.7 2 1 0 2 2 2 0 Fungal mating-type pheromone SR-25 PF10500.9 EGF97929.1 - 4.8 6.7 32.7 0.032 13.8 11.8 2.4 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein SNF2_N PF00176.23 EGF97934.1 - 1.2e-75 254.5 1.1 3.7e-75 252.8 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 EGF97934.1 - 1.3e-07 31.7 0.0 8.6e-07 29.1 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EGF97934.1 - 3e-07 30.2 7.8 6.5e-07 29.1 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGF97934.1 - 9.3e-07 28.6 5.6 1.6e-06 27.8 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGF97934.1 - 1.5e-06 28.2 8.8 3.4e-06 27.1 8.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGF97934.1 - 1.8e-06 27.8 3.9 4.5e-06 26.6 3.9 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGF97934.1 - 4.2e-06 26.5 7.1 1e-05 25.2 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF97934.1 - 4.6e-06 26.9 7.2 1.1e-05 25.6 7.2 1.7 1 0 0 1 1 1 1 Ring finger domain HIRAN PF08797.11 EGF97934.1 - 1.8e-05 24.5 0.0 8.1e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 HIRAN domain zf-RING_5 PF14634.6 EGF97934.1 - 0.00036 20.4 7.3 0.00073 19.5 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain IFT57 PF10498.9 EGF97934.1 - 0.0045 16.0 2.3 0.0045 16.0 2.3 2.1 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 zf-RING_11 PF17123.5 EGF97934.1 - 0.016 14.9 9.0 0.045 13.5 9.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger FAM176 PF14851.6 EGF97934.1 - 0.18 11.4 4.1 0.28 10.8 0.6 2.5 2 0 0 2 2 2 0 FAM176 family Prok-RING_4 PF14447.6 EGF97934.1 - 0.21 11.5 5.2 0.45 10.4 5.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Hexapep PF00132.24 EGF97937.1 - 3.3e-09 36.1 7.8 0.00061 19.4 3.8 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EGF97937.1 - 6.3e-07 27.9 4.3 9.3e-07 27.4 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EGF97937.1 - 3.8e-05 22.8 1.8 0.00012 21.2 0.4 2.0 1 1 1 2 2 2 2 L-fucokinase NTP_transferase PF00483.23 EGF97937.1 - 6.8e-05 22.6 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase CTP_transf_3 PF02348.19 EGF97937.1 - 0.05 13.5 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase NTP_transf_3 PF12804.7 EGF97937.1 - 0.07 13.5 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Egh16-like PF11327.8 EGF97939.1 - 9.7e-26 91.3 0.0 1.8e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 Egh16-like virulence factor DUF4744 PF15918.5 EGF97939.1 - 1.8 9.5 7.3 1.6 9.6 5.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4744) DUF2062 PF09835.9 EGF97940.1 - 0.067 13.0 0.1 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF1206 PF06724.11 EGF97940.1 - 0.17 11.9 0.3 0.33 11.1 0.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Pkinase PF00069.25 EGF97941.1 - 2.2e-52 178.1 0.0 2.8e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF97941.1 - 3.6e-20 72.4 0.0 5.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF97941.1 - 0.028 13.7 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EGF97941.1 - 0.03 14.2 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGF97941.1 - 0.14 11.8 0.2 0.23 11.0 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 EGF97941.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family RVT_3 PF13456.6 EGF97942.1 - 3e-07 30.3 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Kinetochor_Ybp2 PF08568.10 EGF97944.1 - 4.1e-09 35.5 0.2 0.0005 18.7 0.0 2.4 2 1 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Shugoshin_N PF07558.11 EGF97945.1 - 1.1 9.2 5.4 17 5.4 0.0 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region WD40 PF00400.32 EGF97946.1 - 6.7e-06 26.8 1.9 0.00021 22.0 1.4 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF97946.1 - 0.0033 17.7 1.4 21 5.5 0.0 4.6 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SBP56 PF05694.11 EGF97946.1 - 0.076 11.8 0.1 0.79 8.5 0.0 2.1 2 1 0 2 2 2 0 56kDa selenium binding protein (SBP56) FtsJ PF01728.19 EGF97947.1 - 2.4e-68 229.7 0.0 3.8e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Rxt3 PF08642.10 EGF97948.1 - 0.061 14.1 0.5 0.19 12.5 0.5 1.8 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 NPR3 PF03666.13 EGF97948.1 - 0.22 10.3 1.9 0.3 9.8 1.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.6 EGF97948.1 - 0.45 10.2 3.8 0.31 10.7 1.8 1.8 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 EGF97948.1 - 0.58 8.2 6.2 0.75 7.8 5.5 1.4 2 0 0 2 2 2 0 DNA polymerase phi Afi1 PF07792.12 EGF97948.1 - 0.67 10.4 5.1 1.6 9.2 5.1 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TFB6 PF17110.5 EGF97948.1 - 1.3 8.8 4.2 2.2 8.0 4.2 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PorA PF11271.8 EGF97949.1 - 0.077 12.3 0.6 0.12 11.6 0.6 1.2 1 0 0 1 1 1 0 Porin PorA SRP54 PF00448.22 EGF97949.1 - 0.092 12.4 0.2 0.54 9.8 0.0 2.0 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain FAR1 PF03101.15 EGF97949.1 - 0.19 12.4 1.9 0.57 10.9 0.1 2.1 2 0 0 2 2 2 0 FAR1 DNA-binding domain HALZ PF02183.18 EGF97950.1 - 0.0087 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper zf-met PF12874.7 EGF97951.1 - 2.1 8.8 26.9 37 4.9 0.1 7.8 1 1 8 9 9 9 0 Zinc-finger of C2H2 type SUI1 PF01253.22 EGF97952.1 - 9.1e-27 93.4 0.0 1.2e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 RRM_1 PF00076.22 EGF97953.1 - 0.0027 17.5 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAPPC-Trs85 PF12739.7 EGF97954.1 - 3.5e-68 230.5 0.1 4.7e-68 230.0 0.1 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.6 EGF97954.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP PAP2 PF01569.21 EGF97955.1 - 4.7e-11 42.6 11.9 9e-10 38.5 11.9 2.6 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 EGF97955.1 - 0.00046 20.3 0.6 0.24 11.5 0.1 2.5 2 0 0 2 2 2 2 Divergent PAP2 family DUF2649 PF10854.8 EGF97955.1 - 6.8 7.1 7.7 0.3 11.4 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) RecR PF02132.15 EGF97956.1 - 0.027 14.0 1.3 0.05 13.2 1.3 1.4 1 0 0 1 1 1 0 RecR protein RecR PF02132.15 EGF97957.1 - 0.027 14.0 1.3 0.05 13.2 1.3 1.4 1 0 0 1 1 1 0 RecR protein LRS4 PF10422.9 EGF97962.1 - 0.00067 19.3 2.1 0.0008 19.1 2.1 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 DUF641 PF04859.12 EGF97962.1 - 0.0024 18.2 3.2 0.0028 18.0 3.2 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) HIP1_clath_bdg PF16515.5 EGF97962.1 - 0.028 15.0 5.2 0.035 14.7 5.2 1.3 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MerR-DNA-bind PF09278.11 EGF97962.1 - 0.27 11.8 2.3 0.25 11.9 0.8 1.7 1 1 1 2 2 2 0 MerR, DNA binding RIC3 PF15361.6 EGF97962.1 - 6 7.3 6.9 9.4 6.6 6.9 1.4 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Fer2 PF00111.27 EGF97963.1 - 3.2e-07 30.2 0.2 4.8e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1727 PF08353.10 EGF97963.1 - 0.057 13.3 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) Galactosyl_T PF01762.21 EGF97964.1 - 2.8e-09 37.1 0.0 0.0049 16.7 0.0 3.3 2 1 1 3 3 3 3 Galactosyltransferase Abhydrolase_2 PF02230.16 EGF97965.1 - 5.4e-27 95.0 0.0 7.5e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGF97965.1 - 0.0033 18.1 0.0 0.0044 17.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGF97965.1 - 0.0071 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2417 PF10329.9 EGF97965.1 - 0.01 15.3 0.6 0.015 14.7 0.6 1.2 1 0 0 1 1 1 0 Region of unknown function (DUF2417) RRM_1 PF00076.22 EGF97966.1 - 3.4e-41 138.9 0.2 5.8e-18 64.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EGF97966.1 - 4.7e-11 43.6 1.3 1e-08 36.2 0.2 3.5 2 1 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 EGF97966.1 - 0.00013 22.0 0.1 0.015 15.3 0.1 3.7 2 1 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 EGF97966.1 - 0.091 12.6 0.1 28 4.7 0.0 3.5 4 0 0 4 4 4 0 Occluded RNA-recognition motif Mem_trans PF03547.18 EGF97966.1 - 0.11 10.9 0.7 0.13 10.7 0.7 1.2 1 0 0 1 1 1 0 Membrane transport protein RRM_9 PF18444.1 EGF97966.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif Myc_N PF01056.18 EGF97969.1 - 0.49 10.3 9.9 0.72 9.7 9.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Gyro_capsid PF04162.12 EGF97972.1 - 0.029 12.9 0.1 0.033 12.7 0.1 1.1 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) ABC_tran_CTD PF16326.5 EGF97973.1 - 0.035 14.4 2.4 0.45 10.8 2.5 2.2 1 1 0 1 1 1 0 ABC transporter C-terminal domain SNF2_N PF00176.23 EGF97974.1 - 1.2e-60 205.1 0.7 1.9e-60 204.4 0.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGF97974.1 - 8.8e-14 51.8 0.0 2.2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF97974.1 - 0.00016 21.8 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGF97974.1 - 0.00016 21.4 0.0 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 EGF97974.1 - 0.00058 19.7 0.1 0.0038 17.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.6 EGF97974.1 - 0.041 13.7 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGF97985.1 - 3e-11 43.4 0.0 7.1e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF97985.1 - 4.2e-05 23.1 0.0 9.4e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGF97985.1 - 0.079 13.0 0.0 2.6 8.1 0.0 2.6 1 1 1 2 2 2 0 Dynamin family Lipase_GDSL_2 PF13472.6 EGF97988.1 - 9.2e-05 22.9 0.0 0.00012 22.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TFIID_30kDa PF03540.13 EGF97990.1 - 0.068 13.1 0.1 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit Glyco_transf_88 PF16849.5 EGF97993.1 - 0.11 11.3 4.5 0.046 12.7 1.3 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 88 NMO PF03060.15 EGF97993.1 - 1.2 8.4 5.2 0.81 9.0 1.9 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase Miga PF10265.9 EGF97994.1 - 2.7 6.9 10.0 3.5 6.5 10.0 1.2 1 0 0 1 1 1 0 Mitoguardin Sad1_UNC PF07738.13 EGF97995.1 - 8.6e-28 97.0 0.0 1.5e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CHDCT2 PF08074.11 EGF97995.1 - 0.00015 22.0 0.7 0.46 10.6 0.1 2.2 2 0 0 2 2 2 2 CHDCT2 (NUC038) domain Epsilon_antitox PF08998.11 EGF97995.1 - 0.03 14.6 0.8 0.058 13.7 0.1 1.8 2 0 0 2 2 2 0 Bacterial epsilon antitoxin BLOC1_2 PF10046.9 EGF97995.1 - 0.041 14.2 1.9 0.047 14.0 0.8 1.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RhoGEF PF00621.20 EGF97995.1 - 0.076 13.3 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 RhoGEF domain NPV_P10 PF05531.12 EGF97995.1 - 0.19 12.2 0.9 0.62 10.6 0.8 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Phage_int_SAM_6 PF18644.1 EGF97995.1 - 0.26 11.3 2.5 0.66 10.0 0.1 2.6 2 1 1 3 3 3 0 Phage integrase SAM-like domain HSBP1 PF06825.12 EGF97995.1 - 0.43 10.5 1.9 0.4 10.6 0.2 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 LPD24 PF18839.1 EGF97996.1 - 0.04 14.2 0.1 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 Transket_pyr PF02779.24 EGF97997.1 - 0.0022 17.7 0.0 0.0062 16.2 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Peroxidase_2 PF01328.17 EGF97997.1 - 0.035 14.6 0.0 0.069 13.7 0.0 1.4 1 1 0 1 1 1 0 Peroxidase, family 2 YAcAr PF10686.9 EGF97997.1 - 0.058 13.4 0.0 1.1 9.3 0.0 2.5 1 1 1 2 2 2 0 YspA, cpYpsA-related SLOG family CxC1 PF18802.1 EGF97999.1 - 4.9e-19 68.4 0.2 8.8e-19 67.6 0.2 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF97999.1 - 0.0012 19.0 0.1 0.0027 17.8 0.1 1.6 1 1 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases PPV_E2_C PF00511.17 EGF97999.1 - 0.17 12.1 0.9 0.5 10.6 0.0 2.1 1 1 1 2 2 2 0 E2 (early) protein, C terminal DUF2203 PF09969.9 EGF98001.1 - 0.0081 16.9 4.0 0.016 15.9 4.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) PCRF PF03462.18 EGF98001.1 - 0.016 15.1 1.8 0.032 14.1 1.8 1.4 1 0 0 1 1 1 0 PCRF domain CCDC-167 PF15188.6 EGF98001.1 - 0.092 13.1 3.2 0.29 11.5 3.2 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Fez1 PF06818.15 EGF98001.1 - 0.77 10.2 6.9 5.1 7.5 0.5 2.3 1 1 1 2 2 2 0 Fez1 ABC_tran_CTD PF16326.5 EGF98001.1 - 5 7.5 8.7 7.7 6.8 7.5 2.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain MCM_bind PF09739.9 EGF98002.1 - 0.021 13.3 1.6 0.032 12.7 1.6 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SNF2_N PF00176.23 EGF98003.1 - 2e-28 99.1 0.1 2.6e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGF98003.1 - 0.0028 17.4 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGF98003.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGF98004.1 - 5.5e-13 49.2 0.0 6.9e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RXT2_N PF08595.11 EGF98006.1 - 0.63 10.0 7.3 0.38 10.8 3.7 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal TFB6 PF17110.5 EGF98006.1 - 0.74 9.5 4.1 0.42 10.3 1.7 1.7 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH NOA36 PF06524.12 EGF98006.1 - 0.91 8.8 9.4 0.15 11.4 4.2 1.9 2 0 0 2 2 2 0 NOA36 protein DUF4611 PF15387.6 EGF98006.1 - 1.1 9.5 11.9 0.33 11.2 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 EGF98006.1 - 1.1 8.9 14.2 1.1 8.9 8.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 EGF98006.1 - 2 8.8 18.1 9.7 6.7 12.2 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF551 PF04448.12 EGF98006.1 - 5.4 8.0 8.2 0.39 11.7 0.3 3.0 3 2 0 3 3 3 0 Protein of unknown function (DUF551) FAM176 PF14851.6 EGF98006.1 - 7.5 6.2 8.4 4.1 7.1 3.8 2.2 2 0 0 2 2 2 0 FAM176 family CENP-T_C PF15511.6 EGF98007.1 - 4.8e-08 33.1 0.1 5.9e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EGF98007.1 - 8.4e-05 22.7 0.1 0.00012 22.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGF98007.1 - 0.00018 21.9 0.0 0.00023 21.5 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EGF98007.1 - 0.0011 19.4 0.1 0.0012 19.2 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGF98007.1 - 0.0015 18.7 0.1 0.0029 17.8 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGF98007.1 - 0.073 13.2 0.0 0.082 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_L27A PF00828.19 EGF98007.1 - 0.45 11.2 4.0 0.57 10.9 4.0 1.3 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Kelch_6 PF13964.6 EGF98009.1 - 0.061 13.6 0.0 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 Kelch motif Glyco_transf_28 PF03033.20 EGF98010.1 - 1.7e-23 83.2 0.0 5.9e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EGF98010.1 - 0.00021 20.2 0.0 0.00065 18.6 0.0 1.7 2 1 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase GTP_EFTU PF00009.27 EGF98011.1 - 1.5e-18 67.1 0.0 3.9e-18 65.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGF98011.1 - 3.9e-08 33.6 1.1 3.9e-08 33.6 1.1 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EGF98011.1 - 6.4e-07 29.7 0.2 2.1e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D4 PF14578.6 EGF98011.1 - 0.018 14.9 0.6 0.078 12.9 0.2 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 EGF98011.1 - 0.03 14.4 0.1 0.15 12.2 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGF98011.1 - 0.039 13.7 0.2 3 7.6 0.0 3.1 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Alpha_kinase PF02816.18 EGF98012.1 - 1.8e-10 41.2 2.1 2.7e-10 40.7 2.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family zf-CCHC PF00098.23 EGF98013.1 - 0.14 12.3 1.2 0.23 11.6 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Alpha_kinase PF02816.18 EGF98016.1 - 4e-05 23.8 0.0 6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family zf-CCHC PF00098.23 EGF98017.1 - 0.011 15.8 0.3 0.021 14.9 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle YceD PF02620.17 EGF98017.1 - 0.018 15.2 0.2 0.031 14.4 0.2 1.4 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD TFIIA PF03153.13 EGF98017.1 - 0.37 10.7 13.9 0.5 10.3 13.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SET PF00856.28 EGF98017.1 - 0.97 9.8 7.6 29 5.0 7.6 2.1 1 1 0 1 1 1 0 SET domain Imm5 PF14423.6 EGF98017.1 - 2.2 8.5 6.4 3.2 7.9 6.4 1.2 1 0 0 1 1 1 0 Immunity protein Imm5 baeRF_family2 PF18844.1 EGF98017.1 - 4.1 7.4 17.8 0.16 12.0 0.4 2.5 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 KfrA_N PF11740.8 EGF98017.1 - 6.6 7.4 30.7 1.3 9.7 26.9 1.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Pdase_C33_assoc PF14756.6 EGF98020.1 - 0.021 14.8 0.2 0.04 13.8 0.1 1.4 1 1 0 1 1 1 0 Peptidase_C33-associated domain zf-CCHC_4 PF14392.6 EGF98022.1 - 0.022 14.5 0.5 0.044 13.5 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Big_1 PF02369.16 EGF98025.1 - 0.18 11.8 1.4 0.3 11.1 0.2 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) GCM PF03615.15 EGF98028.1 - 0.077 12.9 0.7 0.16 11.9 0.7 1.4 1 0 0 1 1 1 0 GCM motif protein SMBP PF16785.5 EGF98029.1 - 2.4 8.4 10.1 0.64 10.3 3.7 2.3 2 0 0 2 2 2 0 Small metal-binding protein Hid1 PF12722.7 EGF98029.1 - 6.8 4.7 12.5 8.1 4.4 12.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CxC6 PF18721.1 EGF98031.1 - 2.5e-20 72.5 0.5 2.5e-20 72.5 0.5 2.3 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 EGF98031.1 - 3.6e-09 36.7 2.9 3.6e-09 36.7 2.9 2.1 3 0 0 3 3 3 1 CxC5 like cysteine cluster associated with KDZ transposases Sugar_tr PF00083.24 EGF98032.1 - 1.6e-36 126.1 20.8 6.8e-27 94.4 4.9 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGF98032.1 - 4.4e-35 121.3 55.9 3.4e-31 108.5 33.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGF98032.1 - 0.00022 20.7 2.1 0.00022 20.7 2.1 2.7 1 1 2 3 3 3 2 Uncharacterised MFS-type transporter YbfB V-SNARE PF05008.15 EGF98033.1 - 0.0097 16.3 2.4 0.028 14.8 2.4 1.8 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus GST_N_2 PF13409.6 EGF98034.1 - 3.6e-11 43.2 0.0 6.9e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGF98034.1 - 6.6e-11 42.5 0.0 1.2e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGF98034.1 - 2.4e-10 40.6 0.0 4.8e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGF98034.1 - 3.9e-07 30.2 0.0 1.1e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGF98034.1 - 0.00014 22.0 0.0 0.00036 20.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Histone PF00125.24 EGF98036.1 - 1.5e-51 174.2 2.6 1.6e-51 174.1 2.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGF98036.1 - 0.00014 22.5 1.2 0.00016 22.2 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EGF98036.1 - 0.00015 22.1 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGF98036.1 - 0.00019 21.5 0.5 0.00028 20.9 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EGF98036.1 - 0.002 18.4 0.1 0.0038 17.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGF98036.1 - 0.034 14.2 0.2 0.055 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PRAI PF00697.22 EGF98036.1 - 0.15 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Prenyltrans PF00432.21 EGF98037.1 - 5.1e-22 77.3 14.3 0.00012 21.7 0.0 6.1 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Glyco_hydro_47 PF01532.20 EGF98039.1 - 7.4e-06 25.1 0.1 1.4e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Pro_isomerase PF00160.21 EGF98042.1 - 1.5e-33 116.3 0.1 1.7e-33 116.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CxC1 PF18802.1 EGF98043.1 - 1.4e-25 89.4 0.4 3.3e-25 88.2 0.4 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF98043.1 - 1.5e-05 25.1 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGF98043.1 - 4.3e-05 23.3 0.1 0.00015 21.6 0.1 2.0 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGF98043.1 - 0.0084 15.7 0.6 0.039 13.6 0.1 2.1 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase Equine_IAV_S2 PF06502.11 EGF98045.1 - 0.032 14.3 2.1 7.9 6.6 0.0 3.7 1 1 4 5 5 5 0 Equine infectious anaemia virus S2 protein Inhibitor_Mig-6 PF11555.8 EGF98045.1 - 0.14 12.3 1.2 26 5.0 1.2 3.1 1 1 0 1 1 1 0 EGFR receptor inhibitor Mig-6 EAP30 PF04157.16 EGF98046.1 - 0.046 13.0 0.0 2.7 7.2 0.0 2.4 2 0 0 2 2 2 0 EAP30/Vps36 family Mucin PF01456.17 EGF98046.1 - 7.3 6.6 14.5 16 5.4 14.5 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein tRNA_Me_trans PF03054.16 EGF98052.1 - 0.11 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase NESP55 PF06390.12 EGF98052.1 - 0.68 9.5 13.3 0.66 9.5 8.3 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Dor1 PF04124.12 EGF98053.1 - 9.3e-08 31.1 0.1 1.1e-06 27.6 0.1 2.0 1 1 0 1 1 1 1 Dor1-like family DNA_primase_S PF01896.19 EGF98054.1 - 1.4e-13 51.3 3.3 4.8e-06 26.7 1.2 2.3 1 1 1 2 2 2 2 DNA primase small subunit AA_permease PF00324.21 EGF98055.1 - 1.8e-111 373.1 43.2 2.3e-111 372.8 43.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGF98055.1 - 2.7e-30 105.6 44.0 3.9e-30 105.0 44.0 1.2 1 0 0 1 1 1 1 Amino acid permease Myb_DNA-bind_3 PF12776.7 EGF98057.1 - 2.8e-07 31.4 2.4 2.8e-07 31.4 2.4 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 EGF98059.1 - 2.5e-48 164.7 0.0 4.1e-48 164.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF98059.1 - 3.4e-18 65.8 0.0 1.3e-17 64.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF98059.1 - 4.2e-08 32.8 0.0 7e-08 32.1 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGF98059.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGF98059.1 - 0.0044 17.0 0.0 0.0063 16.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGF98059.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGF98059.1 - 0.071 12.0 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Abi_C PF14355.6 EGF98060.1 - 0.0069 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Abortive infection C-terminus Vac7 PF12751.7 EGF98060.1 - 0.058 12.8 0.2 0.093 12.2 0.2 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF1263 PF06882.12 EGF98061.1 - 0.01 15.9 0.9 7.2 6.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) NMT_C PF02799.15 EGF98062.1 - 2.5e-78 262.4 0.0 4e-78 261.7 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EGF98062.1 - 1.2e-71 239.7 0.0 2e-71 239.0 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 EGF98062.1 - 0.0099 16.1 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HGTP_anticodon2 PF12745.7 EGF98062.1 - 0.035 13.6 0.7 0.06 12.9 0.7 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs NTP_transf_9 PF04248.12 EGF98062.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) DUF702 PF05142.12 EGF98063.1 - 0.059 13.9 0.2 0.11 13.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Adap_comp_sub PF00928.21 EGF98066.1 - 1.2e-38 133.0 0.0 1.9e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGF98066.1 - 0.00048 20.1 0.2 0.00081 19.3 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MAM PF00629.23 EGF98066.1 - 0.00088 19.2 0.3 0.0023 17.9 0.0 1.9 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu DUF2340 PF10209.9 EGF98066.1 - 0.006 17.0 0.0 0.022 15.2 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DUF4160 PF13711.6 EGF98067.1 - 0.072 13.4 0.1 0.091 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) Toxin_27 PF08099.11 EGF98068.1 - 0.038 14.1 0.3 0.038 14.1 0.3 1.7 2 0 0 2 2 2 0 Scorpion calcine family NADH_dh_m_C1 PF15088.6 EGF98068.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial CxC5 PF18718.1 EGF98069.1 - 3.8e-31 107.6 10.0 8.2e-30 103.3 8.4 2.4 2 0 0 2 2 2 2 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGF98069.1 - 5.2e-05 23.4 0.0 5.2e-05 23.4 0.0 2.4 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases HSP20 PF00011.21 EGF98070.1 - 8.8e-15 54.7 0.3 9.3e-15 54.6 0.3 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGF98070.1 - 0.00011 21.7 0.1 0.00018 21.0 0.0 1.4 2 0 0 2 2 2 1 HSP20-like domain found in ArsA MtlR PF05068.12 EGF98072.1 - 0.026 14.5 0.7 0.035 14.1 0.7 1.2 1 0 0 1 1 1 0 Mannitol repressor Transketolase_N PF00456.21 EGF98075.1 - 9.1e-16 57.7 0.5 9.6e-15 54.4 0.5 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 EGF98075.1 - 3.1e-08 33.5 0.0 5.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EGF98075.1 - 4.2e-06 26.6 0.1 8.1e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 EGF98075.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II TPP_enzyme_C PF02775.21 EGF98075.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ACOX PF01756.19 EGF98076.1 - 1.8e-48 164.5 0.2 8.5e-48 162.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGF98076.1 - 1.7e-19 69.8 0.0 3.7e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EGF98076.1 - 1.8e-11 44.7 0.6 8.4e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EGF98076.1 - 1.3e-07 32.0 1.5 6.7e-07 29.6 1.0 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain ADH_N PF08240.12 EGF98077.1 - 4.2e-28 97.4 0.8 4.2e-28 97.4 0.8 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGF98077.1 - 2.2e-13 50.3 0.3 3.7e-11 43.1 0.3 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EGF98077.1 - 0.0046 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 EGF98077.1 - 0.009 15.4 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 EGF98077.1 - 0.012 15.1 0.2 0.68 9.4 0.0 3.1 3 1 0 3 3 3 0 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 EGF98077.1 - 0.14 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain CxC1 PF18802.1 EGF98080.1 - 1.8e-13 50.5 0.4 5.9e-13 48.9 0.4 1.7 1 1 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF98080.1 - 0.0096 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF2433 PF10360.9 EGF98084.1 - 0.15 12.1 0.5 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) JmjC PF02373.22 EGF98085.1 - 1.2e-07 32.2 0.3 1.6e-07 31.7 0.3 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 EGF98085.1 - 0.053 13.0 0.0 0.053 13.0 0.0 1.0 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.11 EGF98085.1 - 0.09 12.5 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Cupin domain Epimerase PF01370.21 EGF98086.1 - 1.9e-48 165.0 0.0 2.8e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGF98086.1 - 1e-11 44.9 0.1 5.8e-11 42.4 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGF98086.1 - 0.0006 19.0 0.2 0.036 13.2 0.2 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGF98086.1 - 0.013 14.7 0.1 0.028 13.5 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Glyco_transf_28 PF03033.20 EGF98087.1 - 5.8e-13 49.1 0.0 6.8e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain CPSF_A PF03178.15 EGF98089.1 - 1.9e-66 224.6 0.0 1.8e-43 149.1 0.0 3.0 3 0 0 3 3 3 2 CPSF A subunit region TAP_C PF03943.13 EGF98090.1 - 7.7e-14 51.1 0.1 1.6e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.6 EGF98090.1 - 0.00085 19.1 1.5 0.001 18.8 0.1 1.9 2 0 0 2 2 2 1 UBA-like domain NTF2 PF02136.20 EGF98090.1 - 0.0015 19.1 0.0 0.0049 17.4 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 EGF98090.1 - 0.0017 18.7 5.9 0.0056 17.1 2.9 3.2 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF98090.1 - 0.096 12.5 8.3 0.11 12.3 4.1 3.0 2 1 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 EGF98090.1 - 3.8 8.4 5.1 16 6.5 1.2 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat NGP1NT PF08153.12 EGF98093.1 - 5e-48 162.5 0.0 1.4e-47 161.1 0.0 1.7 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EGF98093.1 - 8.9e-18 64.4 0.0 2.8e-14 53.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF98093.1 - 1.1e-06 28.2 0.0 9.7e-05 21.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGF98093.1 - 0.00078 19.4 0.0 0.0022 17.9 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EGF98093.1 - 0.028 13.9 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 EGF98093.1 - 0.29 11.2 5.3 4 7.5 0.1 3.9 3 1 1 4 4 4 0 Dynamin family DUF1754 PF08555.10 EGF98095.1 - 0.01 16.6 2.3 0.023 15.5 2.3 1.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) zf-RING_11 PF17123.5 EGF98096.1 - 0.27 11.0 7.3 12 5.7 0.2 3.5 3 0 0 3 3 3 0 RING-like zinc finger NIF PF03031.18 EGF98098.1 - 2.7e-17 63.0 0.0 8.5e-17 61.4 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 EGF98098.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Y_phosphatase PF00102.27 EGF98100.1 - 2.8e-14 53.3 0.1 1e-07 31.8 0.1 2.0 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 EGF98100.1 - 0.00039 20.2 0.2 0.0013 18.5 0.1 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGF98100.1 - 0.0034 17.4 0.1 0.0056 16.7 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EGF98100.1 - 0.033 14.3 0.2 0.052 13.7 0.2 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 EGF98100.1 - 0.036 13.7 0.2 0.053 13.1 0.2 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family AAA_19 PF13245.6 EGF98100.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain PIG-L PF02585.17 EGF98104.1 - 4.8e-22 79.0 0.0 6.7e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Retrotran_gag_2 PF14223.6 EGF98106.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Cwf_Cwc_15 PF04889.12 EGF98107.1 - 1.4 8.5 25.8 2.5 7.8 5.1 3.2 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein CFEM PF05730.11 EGF98109.1 - 4e-13 49.2 7.0 4.7e-13 49.0 7.0 1.1 1 0 0 1 1 1 1 CFEM domain Metallothio PF00131.20 EGF98109.1 - 0.02 15.0 4.0 0.45 10.7 0.1 2.1 2 0 0 2 2 2 0 Metallothionein DNA_ligase_A_M PF01068.21 EGF98110.1 - 1e-60 204.9 4.0 1.5e-60 204.3 4.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGF98110.1 - 3.4e-48 164.2 0.0 6.9e-48 163.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGF98110.1 - 3e-22 79.1 0.0 6.4e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EGF98110.1 - 2.9e-05 24.4 0.4 5.2e-05 23.6 0.3 1.5 1 1 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 EGF98110.1 - 0.095 12.7 0.3 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain HeH PF12949.7 EGF98112.1 - 0.0028 17.3 0.1 0.0065 16.2 0.1 1.6 1 0 0 1 1 1 1 HeH/LEM domain ECH_1 PF00378.20 EGF98115.1 - 2.3e-26 92.7 0.0 2.7e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGF98115.1 - 6.6e-11 42.3 0.0 8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CHCH PF06747.13 EGF98116.1 - 0.0024 17.9 0.4 0.0043 17.2 0.4 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 EGF98116.1 - 0.0081 16.2 0.1 0.014 15.4 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like MRG PF05712.13 EGF98117.1 - 1.4e-47 161.5 1.4 2.1e-47 161.0 1.4 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EGF98117.1 - 7.6e-08 32.1 1.4 1.5e-07 31.2 1.4 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 EGF98117.1 - 3.4 7.7 8.8 0.72 9.8 5.0 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain PGP_phosphatase PF09419.10 EGF98118.1 - 1.8e-15 57.0 0.3 1.9e-12 47.2 0.3 3.1 1 1 0 1 1 1 1 Mitochondrial PGP phosphatase WD40 PF00400.32 EGF98119.1 - 1e-28 99.0 11.7 1.2e-06 29.1 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF98119.1 - 1.7e-10 41.0 0.1 0.0019 18.4 0.0 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGF98119.1 - 0.077 11.5 0.0 1.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EGF98122.1 - 3.8e-36 124.8 0.1 5.3e-36 124.3 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EGF98122.1 - 5.7e-34 117.8 0.2 8.8e-34 117.2 0.2 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal MUG113 PF13455.6 EGF98123.1 - 0.021 15.5 1.3 0.38 11.5 0.6 2.8 3 0 0 3 3 3 0 Meiotically up-regulated gene 113 DUF4427 PF14468.6 EGF98123.1 - 0.3 11.1 0.9 0.55 10.3 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) Reprolysin_5 PF13688.6 EGF98125.1 - 8.4e-45 153.3 3.5 3.3e-44 151.4 3.5 2.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EGF98125.1 - 7.5e-39 133.5 0.9 1.3e-38 132.7 0.9 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EGF98125.1 - 2.8e-36 125.3 1.4 2.8e-36 125.3 1.4 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EGF98125.1 - 4.9e-15 56.1 22.5 4.9e-15 56.1 22.5 4.3 3 1 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 EGF98125.1 - 3.9e-10 40.3 0.7 1.3e-09 38.6 0.7 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 EGF98125.1 - 6.7e-06 26.2 7.4 6.7e-06 26.2 7.4 2.5 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 EGF98125.1 - 5.3e-05 23.7 11.2 5.3e-05 23.7 11.2 3.5 2 1 1 3 3 3 1 ADAM cysteine-rich domain Pkinase PF00069.25 EGF98127.1 - 7e-65 219.0 0.1 8.4e-65 218.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF98127.1 - 7.5e-19 68.0 0.0 1.2e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGF98127.1 - 3.8e-08 33.5 0.1 8.6e-07 29.1 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGF98127.1 - 0.011 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGF98127.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGF98127.1 - 0.1 12.1 0.1 0.1 12.1 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Oxysterol_BP PF01237.18 EGF98128.1 - 5.8e-113 377.5 0.1 3.7e-112 374.8 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EGF98128.1 - 1.2e-18 67.2 0.2 2.4e-18 66.2 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGF98128.1 - 0.0006 20.3 0.2 0.0044 17.5 0.1 2.4 2 0 0 2 2 2 1 PH domain BUD22 PF09073.10 EGF98128.1 - 0.81 9.0 5.4 1.7 7.9 4.9 1.7 2 0 0 2 2 2 0 BUD22 AAA PF00004.29 EGF98129.1 - 6.4e-28 97.8 0.0 1e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGF98129.1 - 2.6e-06 27.9 0.0 5.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGF98129.1 - 1.3e-05 25.5 0.2 5.5e-05 23.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGF98129.1 - 3.8e-05 24.2 0.0 8.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EGF98129.1 - 0.0015 18.7 0.0 0.0037 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PduV-EutP PF10662.9 EGF98129.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EGF98129.1 - 0.0026 17.8 0.0 0.0072 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EGF98129.1 - 0.0035 17.0 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGF98129.1 - 0.0038 17.4 0.0 0.007 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGF98129.1 - 0.006 17.0 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EGF98129.1 - 0.0061 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGF98129.1 - 0.0066 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EGF98129.1 - 0.0095 15.9 0.1 0.042 13.8 0.1 2.1 1 1 0 1 1 1 1 NACHT domain TsaE PF02367.17 EGF98129.1 - 0.015 15.3 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGF98129.1 - 0.018 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EGF98129.1 - 0.021 14.0 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Cytidylate_kin PF02224.18 EGF98129.1 - 0.021 14.5 0.0 0.044 13.5 0.0 1.6 2 0 0 2 2 1 0 Cytidylate kinase Rad17 PF03215.15 EGF98129.1 - 0.025 14.5 0.2 0.061 13.2 0.2 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain RuvB_N PF05496.12 EGF98129.1 - 0.026 14.3 0.0 0.064 13.0 0.0 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGF98129.1 - 0.028 14.7 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGF98129.1 - 0.033 13.7 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EGF98129.1 - 0.035 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EGF98129.1 - 0.037 13.7 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGF98129.1 - 0.04 13.7 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.13 EGF98129.1 - 0.045 12.9 0.1 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 EGF98129.1 - 0.073 13.5 0.0 0.8 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGF98129.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGF98129.1 - 0.074 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_3 PF07726.11 EGF98129.1 - 0.17 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KH_1 PF00013.29 EGF98130.1 - 1.3e-37 127.4 11.1 9.5e-09 35.0 0.1 7.7 8 0 0 8 8 8 6 KH domain Acyl_transf_2 PF02273.15 EGF98130.1 - 0.052 12.8 0.1 0.086 12.1 0.1 1.3 1 0 0 1 1 1 0 Acyl transferase Prefoldin_2 PF01920.20 EGF98131.1 - 1e-09 38.3 3.2 2.2e-09 37.2 3.2 1.5 1 1 0 1 1 1 1 Prefoldin subunit SWIRM PF04433.17 EGF98132.1 - 1.1e-30 105.7 0.4 5.8e-30 103.5 0.0 2.4 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EGF98132.1 - 2.8e-22 78.5 5.3 6e-22 77.4 5.3 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EGF98132.1 - 5.5e-07 29.7 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EGF98132.1 - 2.7e-05 23.9 2.1 4.6e-05 23.2 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 EGF98132.1 - 3.7e-05 23.9 0.1 8.8e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain RPS31 PF17067.5 EGF98133.1 - 1.2 9.4 5.7 0.84 9.8 2.1 2.4 2 1 0 2 2 2 0 Ribosomal protein S31e ATG101 PF07855.12 EGF98139.1 - 2.1e-17 63.5 0.2 2.6e-17 63.2 0.2 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 CCT_2 PF09425.10 EGF98139.1 - 0.17 11.8 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 Divergent CCT motif Pyridoxal_deC PF00282.19 EGF98140.1 - 8.9e-23 80.6 0.0 1.2e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGF98140.1 - 1e-09 37.8 0.0 2.4e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGF98140.1 - 0.0074 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EGF98140.1 - 0.097 11.2 0.0 0.28 9.7 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme SecD-TM1 PF13721.6 EGF98140.1 - 0.19 12.2 1.5 4 8.0 0.0 2.9 3 0 0 3 3 3 0 SecD export protein N-terminal TM region Proteasome_A_N PF10584.9 EGF98141.1 - 0.35 10.6 0.8 0.73 9.6 0.1 2.0 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Reprolysin_5 PF13688.6 EGF98142.1 - 5.6e-42 144.1 2.4 5.6e-42 144.1 2.4 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EGF98142.1 - 8.7e-39 133.3 0.1 1.5e-38 132.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EGF98142.1 - 2.8e-36 125.3 0.9 2.8e-36 125.3 0.9 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EGF98142.1 - 1.2e-14 54.8 23.1 1.2e-14 54.8 23.1 4.3 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 EGF98142.1 - 1.5e-11 44.9 0.0 4.3e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 EGF98142.1 - 6.9e-05 22.8 1.8 0.00044 20.2 1.4 2.5 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 EGF98142.1 - 0.0006 20.3 8.4 0.0006 20.3 8.4 4.2 2 1 2 4 4 4 1 ADAM cysteine-rich domain Peptidase_M64 PF09471.10 EGF98142.1 - 0.003 17.1 0.1 0.0051 16.4 0.1 1.2 1 0 0 1 1 1 1 IgA Peptidase M64 Peptidase_M43 PF05572.13 EGF98142.1 - 0.05 13.5 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A YuzL PF14115.6 EGF98143.1 - 0.086 13.3 1.7 3.7 8.1 0.2 2.5 2 0 0 2 2 2 0 YuzL-like protein CDRN PF05174.12 EGF98143.1 - 0.1 12.3 0.0 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus HECT PF00632.25 EGF98146.1 - 7.2e-92 308.1 0.0 8.7e-92 307.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Macoilin PF09726.9 EGF98147.1 - 0.46 9.0 8.9 0.62 8.6 8.9 1.1 1 0 0 1 1 1 0 Macoilin family Hexokinase_2 PF03727.16 EGF98151.1 - 5.1e-83 278.2 0.2 8.3e-83 277.5 0.2 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGF98151.1 - 2.8e-71 239.5 0.0 5.3e-71 238.7 0.0 1.5 1 0 0 1 1 1 1 Hexokinase IHHNV_capsid PF16530.5 EGF98153.1 - 0.094 11.8 0.3 0.17 11.0 0.3 1.3 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid Mt_ATP-synt_D PF05873.12 EGF98154.1 - 7.3e-17 61.6 0.8 1e-16 61.1 0.7 1.2 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Rax2 PF12768.7 EGF98154.1 - 0.088 12.3 0.3 0.12 11.8 0.3 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Pkinase PF00069.25 EGF98155.1 - 1.1e-49 169.2 0.0 3e-48 164.5 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF98155.1 - 6.6e-22 78.0 0.0 1.6e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF98155.1 - 2e-06 27.3 0.0 3.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGF98155.1 - 0.0002 20.5 1.8 0.00042 19.4 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 EGF98155.1 - 0.00036 20.2 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EGF98155.1 - 0.00072 18.4 0.0 0.00072 18.4 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGF98155.1 - 0.0036 17.3 0.1 0.0063 16.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGF98155.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EGF98155.1 - 0.21 10.9 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAM-associated PF14303.6 EGF98156.1 - 1.3e-06 29.3 2.8 1.3e-06 29.3 2.8 3.8 2 2 1 3 3 3 1 No apical meristem-associated C-terminal domain Sec20 PF03908.13 EGF98156.1 - 0.89 9.5 0.0 0.89 9.5 0.0 2.5 2 1 0 2 2 2 0 Sec20 Ole-e-6 PF09253.10 EGF98157.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Pollen allergen ole e 6 Glyco_hydro_77 PF02446.17 EGF98158.1 - 0.086 11.7 0.0 0.1 11.5 0.0 1.0 1 0 0 1 1 1 0 4-alpha-glucanotransferase BES1_N PF05687.13 EGF98161.1 - 0.012 16.0 0.1 0.094 13.1 0.0 2.3 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal EFP_N PF08207.12 EGF98161.1 - 0.16 12.0 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain DHQ_synthase PF01761.20 EGF98162.1 - 1.8e-52 178.1 0.0 2.6e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EGF98162.1 - 1.8e-11 44.2 0.0 3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Pox_C4_C10 PF03336.13 EGF98162.1 - 0.096 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein NAD_binding_4 PF07993.12 EGF98163.1 - 2.6e-38 131.7 0.0 5e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGF98163.1 - 3.4e-24 85.2 0.0 2.3e-22 79.2 0.0 3.1 1 1 1 2 2 2 1 AMP-binding enzyme PP-binding PF00550.25 EGF98163.1 - 3.8e-08 33.6 0.0 1.2e-07 31.9 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EGF98163.1 - 3.7e-05 23.3 0.0 8.8e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0270 PF06794.12 EGF98163.1 - 0.03 14.4 0.3 0.078 13.1 0.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) KR PF08659.10 EGF98163.1 - 0.048 13.6 0.1 0.15 12.0 0.1 1.8 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 EGF98163.1 - 0.18 10.9 0.0 0.48 9.5 0.0 1.7 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sec7 PF01369.20 EGF98164.1 - 9.5e-73 243.8 0.1 5.8e-72 241.2 0.2 2.4 2 1 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 EGF98164.1 - 8e-45 152.6 4.9 8e-45 152.6 4.9 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGF98164.1 - 1.2e-31 108.4 7.9 8.4e-31 105.7 0.7 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DCB PF16213.5 EGF98164.1 - 9.5e-12 44.9 0.2 1.1e-08 34.9 0.0 3.6 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 GATase_2 PF00310.21 EGF98166.1 - 8.2e-10 38.0 0.0 8.6e-10 37.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.14 EGF98167.1 - 2.9e-12 46.6 0.0 3.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Glutamate synthase central domain Pou PF00157.17 EGF98168.1 - 0.078 13.0 1.0 8.6 6.4 0.1 2.4 1 1 1 2 2 2 0 Pou domain - N-terminal to homeobox domain IFT57 PF10498.9 EGF98171.1 - 0.016 14.2 0.9 0.023 13.7 0.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Snapin_Pallidin PF14712.6 EGF98171.1 - 0.027 14.9 0.7 0.055 13.9 0.7 1.5 1 0 0 1 1 1 0 Snapin/Pallidin DEPP PF15343.6 EGF98177.1 - 0.046 13.8 0.1 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Decidual protein induced by progesterone family Pneumo_att_G PF05539.11 EGF98178.1 - 0.24 11.0 8.5 0.33 10.5 8.5 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G YqfQ PF14181.6 EGF98178.1 - 2.9 8.1 11.6 0.77 9.9 8.7 1.6 2 0 0 2 2 2 0 YqfQ-like protein Ndc1_Nup PF09531.10 EGF98178.1 - 4.3 5.9 5.6 4.4 5.9 5.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 EGF98178.1 - 6.3 5.4 6.4 6.4 5.4 6.4 1.2 1 0 0 1 1 1 0 Presenilin Fib_alpha PF08702.10 EGF98179.1 - 0.0026 18.0 0.7 0.0035 17.5 0.7 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family THOC7 PF05615.13 EGF98179.1 - 0.059 13.7 0.2 0.084 13.2 0.2 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 DUF5082 PF16888.5 EGF98179.1 - 0.075 13.3 0.3 0.075 13.3 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) BRE1 PF08647.11 EGF98179.1 - 0.17 12.0 0.2 0.48 10.5 0.2 1.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Syntaxin_2 PF14523.6 EGF98181.1 - 0.036 14.4 0.8 0.14 12.6 0.1 2.4 2 0 0 2 2 2 0 Syntaxin-like protein MIP-T3_C PF17749.1 EGF98181.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.3 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region DUF5042 PF16445.5 EGF98183.1 - 0.066 11.6 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) ADK_lid PF05191.14 EGF98185.1 - 0.055 13.5 0.2 1.3 9.1 0.0 2.6 2 1 0 2 2 2 0 Adenylate kinase, active site lid PTPlike_phytase PF14566.6 EGF98188.1 - 4.9e-109 361.4 0.0 5.3e-43 146.8 0.0 3.4 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 EGF98188.1 - 4.7e-06 26.4 0.0 0.2 11.5 0.0 3.6 4 0 0 4 4 4 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGF98188.1 - 0.0003 20.4 0.3 0.14 11.7 0.0 3.2 3 0 0 3 3 3 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGF98188.1 - 0.011 15.8 0.0 4.8 7.1 0.0 3.5 3 0 0 3 3 3 0 Tyrosine phosphatase family NAPRTase PF04095.16 EGF98189.1 - 8.4e-56 189.3 0.0 1.1e-55 188.9 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EGF98189.1 - 2.9e-34 118.1 0.3 4.8e-34 117.4 0.3 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain PEX-2N PF09263.10 EGF98189.1 - 0.14 12.5 0.4 0.71 10.2 0.1 2.1 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal Mob1_phocein PF03637.17 EGF98191.1 - 5.3e-75 251.1 0.2 6.3e-75 250.9 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family SYS1 PF09801.9 EGF98192.1 - 2.8e-23 82.7 5.3 5.5e-17 62.2 2.3 2.2 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network p450 PF00067.22 EGF98193.1 - 1.2e-65 222.1 0.0 1.5e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HycI PF01750.18 EGF98194.1 - 0.025 14.4 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase maturation protease DUF3717 PF12512.8 EGF98195.1 - 0.39 10.6 1.7 1.4 8.8 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3717) Trs65 PF12735.7 EGF98196.1 - 0.00022 20.8 7.8 0.053 12.9 0.0 2.5 2 1 0 2 2 2 2 TRAPP trafficking subunit Trs65 Drf_GBD PF06371.13 EGF98197.1 - 4e-19 68.9 0.2 4e-19 68.9 0.2 2.9 3 2 0 3 3 3 1 Diaphanous GTPase-binding Domain Flagellin_C PF00700.21 EGF98197.1 - 4.7 7.6 7.4 2.8 8.3 0.4 3.3 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region DUF3405 PF11885.8 EGF98198.1 - 0.096 11.3 0.1 0.14 10.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) GCV_T PF01571.21 EGF98199.1 - 1.3e-82 277.0 0.0 1.7e-82 276.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EGF98199.1 - 7.1e-18 64.3 0.0 1.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 EGF98199.1 - 2.1e-05 24.7 0.0 0.0003 21.0 0.0 2.1 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family RNB PF00773.19 EGF98200.1 - 1.5e-96 323.6 0.0 2.1e-96 323.1 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 EGF98200.1 - 1.2e-23 82.9 0.9 2.6e-23 81.8 0.9 1.6 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 EGF98200.1 - 1.2e-20 73.8 0.0 3.1e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 EGF98200.1 - 7.7e-17 61.1 0.0 3.1e-16 59.2 0.0 2.1 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EGF98200.1 - 3.1e-14 53.4 0.9 1.5e-13 51.2 0.0 2.3 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 EGF98200.1 - 2.5e-06 27.6 0.3 0.0041 17.2 0.0 4.4 5 0 0 5 5 5 1 Cold shock domain OB_RNB PF08206.11 EGF98200.1 - 0.00054 19.6 0.8 0.058 13.1 0.1 2.6 2 0 0 2 2 2 1 Ribonuclease B OB domain SF1-HH PF16275.5 EGF98201.1 - 2e-38 131.2 0.1 4.5e-38 130.1 0.1 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 EGF98201.1 - 2.6e-06 27.2 0.1 5.3e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 EGF98201.1 - 0.00023 21.1 0.8 0.00048 20.1 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle Abhydrolase_1 PF00561.20 EGF98204.1 - 4.8e-06 26.4 0.0 9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGF98204.1 - 0.0011 19.6 0.4 0.0027 18.4 0.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DEAD PF00270.29 EGF98209.1 - 6.1e-35 120.6 0.1 1.7e-34 119.1 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF98209.1 - 1.1e-22 80.5 0.0 5.1e-22 78.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF98209.1 - 0.004 17.2 0.0 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGF98209.1 - 0.022 14.0 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase NFACT-R_1 PF05670.13 EGF98210.1 - 1.4e-39 135.1 0.0 2.4e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain OPT PF03169.15 EGF98214.1 - 2.1e-52 178.6 25.1 1.1e-31 110.2 10.9 3.4 2 2 0 2 2 2 2 OPT oligopeptide transporter protein OPT PF03169.15 EGF98215.1 - 7.4e-10 38.1 5.4 7.4e-10 38.1 5.4 1.8 2 0 0 2 2 2 1 OPT oligopeptide transporter protein Adeno_100 PF02438.16 EGF98218.1 - 0.098 10.8 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Late 100kD protein OPT PF03169.15 EGF98219.1 - 4.6e-120 402.1 36.3 7.5e-120 401.4 36.3 1.3 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Proteasome PF00227.26 EGF98220.1 - 6.3e-50 169.3 0.1 7.9e-50 169.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit GMC_oxred_N PF00732.19 EGF98221.1 - 5.8e-51 173.6 0.0 1.3e-50 172.5 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGF98221.1 - 1.6e-40 138.9 0.0 2.9e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EGF98221.1 - 1.5e-05 24.2 0.0 2.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGF98221.1 - 2.6e-05 23.5 0.0 0.027 13.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EGF98221.1 - 0.003 16.8 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGF98221.1 - 0.0041 16.8 0.1 0.01 15.4 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGF98221.1 - 0.0061 16.8 0.0 0.02 15.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGF98221.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Cwf_Cwc_15 PF04889.12 EGF98222.1 - 6.2 6.5 15.7 18 5.0 11.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein EMP70 PF02990.16 EGF98225.1 - 8.1e-189 628.6 1.6 1.2e-188 628.1 1.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Rax2 PF12768.7 EGF98226.1 - 9.6e-33 113.4 5.8 1.9e-32 112.5 1.3 3.3 2 2 2 4 4 4 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 EGF98226.1 - 1.8e-05 24.2 0.1 3.5e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGF98226.1 - 5.7e-05 22.9 0.2 0.00016 21.4 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGF98226.1 - 0.0011 18.6 0.1 0.0029 17.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 EGF98226.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 SH3 domain Kelch_1 PF01344.25 EGF98226.1 - 0.099 12.2 10.0 0.22 11.1 0.0 5.4 5 0 0 5 5 5 0 Kelch motif Kelch_6 PF13964.6 EGF98226.1 - 1.1 9.6 20.6 0.25 11.7 0.2 7.3 7 1 1 8 8 8 0 Kelch motif PTS_IIA PF02255.16 EGF98228.1 - 0.92 9.6 4.0 4 7.6 0.2 2.6 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Med13_C PF06333.12 EGF98230.1 - 1.1e-11 44.6 0.0 1.1e-11 44.6 0.0 5.5 3 1 2 5 5 5 1 Mediator complex subunit 13 C-terminal domain DUF676 PF05057.14 EGF98231.1 - 6.9e-06 25.7 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGF98231.1 - 0.00081 19.3 0.1 0.0021 18.0 0.0 1.5 1 1 1 2 2 2 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGF98231.1 - 0.0033 17.2 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.18 EGF98231.1 - 0.039 13.5 0.0 0.19 11.2 0.0 1.9 1 1 0 1 1 1 0 Lipase (class 2) Abhydrolase_1 PF00561.20 EGF98231.1 - 0.053 13.1 0.1 0.48 10.0 0.0 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_A22B PF04258.13 EGF98231.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Signal peptide peptidase DUF2974 PF11187.8 EGF98231.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF676 PF05057.14 EGF98232.1 - 1.5e-05 24.6 0.1 2.5e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGF98232.1 - 0.00017 21.5 0.1 0.00028 20.8 0.1 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGF98232.1 - 0.00092 19.0 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EGF98232.1 - 0.0016 18.1 0.1 0.011 15.5 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Sugarporin_N PF11471.8 EGF98233.1 - 0.00013 21.9 0.2 0.00013 21.9 0.2 2.1 2 0 0 2 2 2 1 Maltoporin periplasmic N-terminal extension XhlA PF10779.9 EGF98233.1 - 0.15 12.3 2.2 0.24 11.6 2.2 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Macoilin PF09726.9 EGF98233.1 - 1.1 7.7 7.1 0.26 9.8 4.2 1.4 1 1 0 1 1 1 0 Macoilin family Lectin_N PF03954.14 EGF98233.1 - 1.9 8.2 5.2 2.7 7.7 5.2 1.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain TAP42 PF04177.12 EGF98234.1 - 1.7e-77 260.7 8.1 1.9e-77 260.5 8.1 1.0 1 0 0 1 1 1 1 TAP42-like family Adaptin_N PF01602.20 EGF98235.1 - 8.8e-142 473.3 8.7 1e-141 473.1 8.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EGF98235.1 - 4.8e-18 65.5 0.4 1.3e-17 64.1 0.1 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 EGF98235.1 - 5.2e-06 26.6 9.5 9.2e-05 22.5 0.2 4.5 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGF98235.1 - 0.00081 19.7 0.8 7.2 7.1 0.0 4.4 5 0 0 5 5 5 1 HEAT repeats RIX1 PF08167.12 EGF98235.1 - 0.1 12.4 0.1 0.79 9.4 0.0 2.5 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis DUF1064 PF06356.11 EGF98236.1 - 0.0013 19.0 0.9 0.0027 18.1 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1064) Trans_coact PF16805.5 EGF98236.1 - 0.066 13.3 0.2 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Phage late-transcription coactivator CENP-F_leu_zip PF10473.9 EGF98236.1 - 0.47 10.5 12.4 0.98 9.4 12.4 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 VHS PF00790.19 EGF98237.1 - 6.9e-22 77.8 0.3 1.3e-21 76.9 0.3 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EGF98237.1 - 3.8e-08 33.5 2.7 7.2e-06 26.2 0.1 3.1 3 0 0 3 3 3 2 GAT domain DUF1539 PF07560.11 EGF98237.1 - 0.02 14.9 2.7 0.029 14.5 0.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Tail_P2_I PF09684.10 EGF98240.1 - 0.046 13.6 0.1 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Phage tail protein (Tail_P2_I) MIP PF00230.20 EGF98244.1 - 7.4e-29 101.1 6.7 9.3e-29 100.7 6.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3493 PF11998.8 EGF98244.1 - 0.097 12.8 0.1 0.34 11.1 0.1 1.9 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 Peptidase_M1 PF01433.20 EGF98245.1 - 7e-40 136.9 0.0 1.2e-39 136.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EGF98245.1 - 1.9e-37 127.8 0.2 3.6e-37 126.9 0.2 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EGF98245.1 - 6.8e-24 85.1 0.0 1e-23 84.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 EGF98245.1 - 0.073 13.5 1.5 2 8.8 1.5 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase FTR_C PF02741.15 EGF98246.1 - 0.069 13.2 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 FTR, proximal lobe Ribosomal_S18 PF01084.20 EGF98248.1 - 1e-13 51.3 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 CDC24 PF06395.11 EGF98249.1 - 0.048 13.9 0.5 0.33 11.2 0.1 2.1 2 0 0 2 2 2 0 CDC24 Calponin DUF3730 PF12530.8 EGF98249.1 - 0.06 12.9 0.4 0.074 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) CCSAP PF15748.5 EGF98251.1 - 0.028 14.6 21.5 0.032 14.4 21.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Macoilin PF09726.9 EGF98251.1 - 0.15 10.6 14.5 0.17 10.4 14.5 1.0 1 0 0 1 1 1 0 Macoilin family GAGA_bind PF06217.12 EGF98251.1 - 0.17 12.2 10.7 0.18 12.0 10.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DAG_kinase_N PF14513.6 EGF98251.1 - 0.19 12.0 7.5 0.25 11.6 7.5 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus RR_TM4-6 PF06459.12 EGF98251.1 - 1.7 8.4 15.7 2 8.2 15.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4758 PF15950.5 EGF98251.1 - 2.9 8.2 12.2 4.2 7.7 12.2 1.2 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein Neur_chan_memb PF02932.16 EGF98251.1 - 3.2 7.7 8.3 3.5 7.6 8.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CCDC106 PF15794.5 EGF98251.1 - 7.5 6.2 19.4 10 5.8 19.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 AIF_C PF14721.6 EGF98251.1 - 9.4 6.6 8.2 15 6.0 8.2 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MerR-DNA-bind PF09278.11 EGF98252.1 - 6.5 7.4 8.0 6 7.5 0.1 3.4 2 1 2 4 4 4 0 MerR, DNA binding Lipase_GDSL_2 PF13472.6 EGF98253.1 - 0.0018 18.7 0.0 0.0052 17.2 0.0 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TetR_C_4 PF08359.11 EGF98256.1 - 0.045 13.9 0.5 0.076 13.2 0.4 1.5 1 1 0 1 1 1 0 YsiA-like protein, C-terminal region Band_7 PF01145.25 EGF98256.1 - 0.063 13.3 1.7 0.091 12.8 1.7 1.2 1 0 0 1 1 1 0 SPFH domain / Band 7 family Dor1 PF04124.12 EGF98258.1 - 0.069 11.8 0.8 0.34 9.5 0.2 2.2 2 1 1 3 3 3 0 Dor1-like family Profilin PF00235.19 EGF98259.1 - 0.0094 16.2 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 1 Profilin CAF1A PF12253.8 EGF98260.1 - 4.8 7.4 7.9 0.85 9.8 3.5 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A DUF3399 PF11879.8 EGF98260.1 - 7.2 7.0 8.9 0.28 11.5 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) Peptidase_M16 PF00675.20 EGF98264.1 - 4.7e-06 26.6 0.1 5e-06 26.6 0.1 1.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) CPSF100_C PF13299.6 EGF98267.1 - 2.6e-07 31.0 0.0 5.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal FOXP-CC PF16159.5 EGF98268.1 - 4.3 8.1 9.2 27 5.5 0.1 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain Luteo_P1-P2 PF08467.10 EGF98269.1 - 0.088 12.0 0.1 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Luteovirus RNA polymerase P1-P2/replicase ABC_tran PF00005.27 EGF98274.1 - 1.3e-10 41.9 1.1 4.8e-10 40.1 0.4 2.1 1 1 1 2 2 2 1 ABC transporter SMC_N PF02463.19 EGF98274.1 - 0.0007 19.1 0.1 0.0021 17.5 0.0 1.7 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Lsm_C PF14894.6 EGF98274.1 - 0.035 13.9 0.1 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Lsm C-terminal Calycin_like PF13944.6 EGF98274.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Calycin-like beta-barrel domain IstB_IS21 PF01695.17 EGF98274.1 - 0.12 12.1 0.0 5.2 6.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2052 PF09747.9 EGF98275.1 - 0.0038 17.4 3.7 0.0084 16.3 3.7 1.5 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) GAGA_bind PF06217.12 EGF98275.1 - 0.63 10.3 14.7 0.081 13.2 10.0 1.9 2 0 0 2 2 2 0 GAGA binding protein-like family PPL5 PF18168.1 EGF98275.1 - 0.84 8.9 6.1 1.6 8.0 6.1 1.5 1 0 0 1 1 1 0 Prim-pol family 5 Noggin PF05806.12 EGF98275.1 - 3.9 7.3 7.3 12 5.8 7.3 1.7 1 0 0 1 1 1 0 Noggin Hid1 PF12722.7 EGF98275.1 - 9.4 4.2 7.8 14 3.6 7.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Vfa1 PF08432.10 EGF98275.1 - 9.5 6.5 21.3 5.5 7.3 17.9 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 AFT PF08731.11 EGF98282.1 - 0.0023 18.3 0.1 0.0023 18.3 0.1 2.1 3 0 0 3 3 3 1 Transcription factor AFT Peptidase_S66 PF02016.15 EGF98282.1 - 0.033 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain BCLP PF12304.8 EGF98282.1 - 0.091 12.3 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Beta-casein like protein Methyltransf_4 PF02390.17 EGF98283.1 - 0.0073 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Glyco_transf_41 PF13844.6 EGF98284.1 - 0.001 17.6 0.0 0.0012 17.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 41 RCC1_2 PF13540.6 EGF98285.1 - 0.027 14.3 7.6 5.3 7.0 0.0 3.6 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat Gp_dh_N PF00044.24 EGF98286.1 - 3.7e-39 133.1 0.1 6.8e-39 132.3 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 EGF98286.1 - 4.2e-23 81.7 0.0 6.6e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 EGF98286.1 - 0.087 12.2 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_16 PF00722.21 EGF98289.1 - 0.00093 18.7 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DNA_ligase_A_M PF01068.21 EGF98289.1 - 0.02 14.5 0.0 0.021 14.4 0.0 1.0 1 0 0 1 1 1 0 ATP dependent DNA ligase domain GMC_oxred_N PF00732.19 EGF98292.1 - 4.2e-10 39.5 0.1 5.6e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase TFIIA_gamma_N PF02268.16 EGF98293.1 - 0.00072 19.5 0.0 0.0033 17.4 0.0 2.0 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit, helical domain Pro_dh PF01619.18 EGF98294.1 - 0.066 12.7 0.1 0.066 12.7 0.1 1.1 1 0 0 1 1 1 0 Proline dehydrogenase Polysacc_deac_1 PF01522.21 EGF98298.1 - 6.9e-27 93.8 0.0 5.1e-26 91.0 0.0 2.0 1 1 1 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGF98298.1 - 3.6e-06 26.4 0.0 1.4e-05 24.4 0.0 1.7 1 1 0 2 2 2 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 EGF98298.1 - 3.7e-05 23.5 0.0 5.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) RCC1_2 PF13540.6 EGF98299.1 - 0.0068 16.2 2.2 12 5.8 0.1 3.3 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Tna_leader PF08053.11 EGF98299.1 - 0.65 10.0 2.7 46 4.2 0.1 2.9 3 0 0 3 3 3 0 Tryptophanase operon leader peptide ASF1_hist_chap PF04729.13 EGF98302.1 - 5.7e-69 231.0 0.1 8.1e-69 230.5 0.1 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone EF_assoc_2 PF08356.12 EGF98303.1 - 4.7e-14 52.2 0.0 7.1e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 EF hand associated V1R PF03402.14 EGF98303.1 - 0.027 14.1 2.6 3.6 7.1 0.5 2.4 2 1 1 3 3 3 0 Vomeronasal organ pheromone receptor family, V1R DUF5381 PF17353.2 EGF98306.1 - 0.31 10.8 1.5 1.9 8.2 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5381) DUF3311 PF11755.8 EGF98307.1 - 0.059 13.3 5.0 3.6 7.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) DUF4680 PF15730.5 EGF98307.1 - 0.14 12.5 0.4 1.7 9.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) Sigma70_ECF PF07638.11 EGF98307.1 - 0.37 10.6 0.9 28 4.5 0.1 2.2 2 0 0 2 2 2 0 ECF sigma factor GMC_oxred_N PF00732.19 EGF98308.1 - 4.4e-10 39.4 0.1 5.9e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase KDZ PF18758.1 EGF98310.1 - 4e-52 177.0 2.3 7.2e-52 176.2 0.2 2.3 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGF98310.1 - 5.2e-29 100.5 0.0 1.3e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF98310.1 - 0.00045 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGF98310.1 - 0.012 15.4 0.0 0.043 13.7 0.0 1.9 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases PI_PP_I PF18363.1 EGF98311.1 - 0.1 12.8 0.3 0.31 11.3 0.1 2.0 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Pox_Ag35 PF03286.14 EGF98313.1 - 0.0031 17.4 8.3 0.0034 17.2 8.3 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein RPN2_C PF18004.1 EGF98313.1 - 0.16 11.9 4.6 0.19 11.6 4.6 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PBP1_TM PF14812.6 EGF98313.1 - 0.21 12.0 14.1 0.15 12.4 12.7 1.5 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ORC6 PF05460.13 EGF98313.1 - 0.42 9.8 10.9 0.49 9.6 10.9 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NOA36 PF06524.12 EGF98313.1 - 0.51 9.6 5.5 0.55 9.5 5.5 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 EGF98313.1 - 0.58 9.8 8.9 0.31 10.7 7.2 1.4 1 1 1 2 2 2 0 FAM176 family Spem1 PF15670.5 EGF98313.1 - 0.95 9.0 4.4 0.93 9.0 4.4 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 Presenilin PF01080.17 EGF98313.1 - 3.2 6.4 5.0 3.2 6.4 5.0 1.0 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 EGF98313.1 - 3.5 6.9 5.9 4.1 6.7 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CxC1 PF18802.1 EGF98315.1 - 3.5e-19 68.9 0.2 6.9e-19 67.9 0.2 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF98315.1 - 8.3e-09 35.6 0.0 1.5e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGF98315.1 - 0.018 14.9 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases AlkA_N PF06029.11 EGF98315.1 - 0.8 10.0 5.4 2.3 8.5 0.6 4.1 5 1 1 6 6 6 0 AlkA N-terminal domain Fez1 PF06818.15 EGF98315.1 - 1.4 9.3 8.1 8.3 6.8 8.2 2.2 1 1 0 1 1 1 0 Fez1 CxC5 PF18718.1 EGF98317.1 - 8e-28 96.9 2.2 1.6e-27 95.9 2.2 1.5 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases zf-TRM13_CCCH PF11722.8 EGF98319.1 - 0.039 13.7 0.3 45 3.9 0.0 3.1 3 0 0 3 3 3 0 CCCH zinc finger in TRM13 protein Pheromone PF08015.11 EGF98319.1 - 0.078 14.0 2.8 0.25 12.4 0.0 2.7 3 0 0 3 3 3 0 Fungal mating-type pheromone Pax7 PF12360.8 EGF98319.1 - 0.2 11.9 4.9 16 5.8 0.0 3.5 2 2 3 5 5 5 0 Paired box protein 7 YpM PF09144.10 EGF98319.1 - 0.29 11.3 2.1 0.89 9.7 0.8 1.8 1 1 1 2 2 2 0 Yersinia pseudo-tuberculosis mitogen Metallophos PF00149.28 EGF98320.1 - 7.6e-34 118.0 0.0 9.6e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EGF98320.1 - 0.0064 16.2 0.0 0.0089 15.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 EGF98320.1 - 0.0087 16.5 0.1 0.024 15.1 0.1 1.8 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain NifU_N PF01592.16 EGF98321.1 - 0.052 13.7 0.1 0.54 10.4 0.0 2.1 1 1 1 2 2 2 0 NifU-like N terminal domain Cyt-b5 PF00173.28 EGF98324.1 - 1.5e-17 63.5 3.1 1.5e-17 63.5 0.1 2.3 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EGF98324.1 - 2.4e-13 50.6 13.6 2.4e-13 50.6 13.6 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Citrate_bind PF16114.5 EGF98326.1 - 1.4e-88 295.0 0.0 3.4e-88 293.8 0.0 1.7 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 EGF98326.1 - 3.3e-19 69.2 0.0 2.6e-16 59.6 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 EGF98326.1 - 6.6e-16 58.5 0.1 2.1e-15 56.9 0.1 1.9 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 EGF98326.1 - 1.2e-11 45.1 0.0 3.3e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 EGF98326.1 - 8e-08 32.2 0.1 1e-05 25.4 0.0 2.7 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 EGF98326.1 - 1.1e-07 31.7 0.0 1.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain MSP1_C PF07462.11 EGF98327.1 - 0.0031 16.3 0.4 0.0031 16.3 0.4 1.6 2 0 0 2 2 2 1 Merozoite surface protein 1 (MSP1) C-terminus RE_MjaI PF09568.10 EGF98328.1 - 0.018 14.8 3.6 0.039 13.8 3.6 1.5 1 0 0 1 1 1 0 MjaI restriction endonuclease Sdh5 PF03937.16 EGF98330.1 - 6.7e-22 77.2 0.2 8.8e-22 76.9 0.2 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase LPD11 PF18824.1 EGF98330.1 - 0.059 13.5 0.1 0.23 11.6 0.1 2.0 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 NAM-associated PF14303.6 EGF98332.1 - 8.7e-15 55.8 9.1 8.7e-15 55.8 9.1 2.8 2 1 0 2 2 2 1 No apical meristem-associated C-terminal domain EccE PF11203.8 EGF98332.1 - 0.077 13.3 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE WD40 PF00400.32 EGF98333.1 - 8.8e-46 153.0 12.5 2.4e-06 28.2 0.0 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 EGF98333.1 - 9.5e-09 34.9 1.4 2.2e-08 33.8 1.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGF98333.1 - 2.2e-08 33.8 0.3 4.4e-08 32.9 0.3 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 EGF98333.1 - 1.2e-06 27.5 7.0 1.6 7.3 0.0 5.9 1 1 5 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGF98333.1 - 4.5e-06 26.9 1.5 0.038 14.3 0.1 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EGF98333.1 - 0.00014 21.7 0.9 0.00055 19.8 0.2 2.4 2 1 1 3 3 3 1 F-box WD40_like PF17005.5 EGF98333.1 - 0.0018 17.7 0.0 0.0082 15.5 0.0 1.9 2 0 0 2 2 2 1 WD40-like domain DUF3244 PF11589.8 EGF98333.1 - 0.74 9.9 4.5 0.3 11.2 0.4 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3244) OPT PF03169.15 EGF98335.1 - 3e-45 155.0 20.2 4.5e-33 114.8 9.9 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein DUF4118 PF13493.6 EGF98335.1 - 1.9 8.3 15.9 0.67 9.8 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) HsbA PF12296.8 EGF98336.1 - 0.00033 21.1 0.0 0.00089 19.7 0.0 1.8 1 1 0 1 1 1 1 Hydrophobic surface binding protein A RSN1_7TM PF02714.15 EGF98337.1 - 1.8e-70 237.4 19.8 3.9e-70 236.3 19.8 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGF98337.1 - 3.4e-37 127.6 2.6 3.4e-37 127.6 2.6 3.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGF98337.1 - 5.9e-34 117.8 1.2 2.4e-33 115.8 0.0 2.2 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Nod1 PF17114.5 EGF98337.1 - 0.075 13.2 0.1 0.63 10.2 0.1 2.3 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 TMC PF07810.13 EGF98337.1 - 9.9 6.8 8.8 30 5.3 1.8 2.9 1 1 1 2 2 2 0 TMC domain NAD_binding_4 PF07993.12 EGF98341.1 - 2.2e-66 223.7 0.0 3.2e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGF98341.1 - 6.1e-65 219.5 0.0 8.9e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EGF98341.1 - 3e-10 40.3 0.0 1.2e-09 38.3 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 EGF98341.1 - 1.4e-07 31.3 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 EGF98341.1 - 5.2e-06 25.4 0.1 2.5e-05 23.2 0.1 1.9 1 1 0 1 1 1 1 Condensation domain 3Beta_HSD PF01073.19 EGF98341.1 - 0.00021 20.4 0.0 0.0006 18.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EGF98341.1 - 0.00048 21.0 0.1 0.0033 18.4 0.0 2.5 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Polysacc_deac_1 PF01522.21 EGF98342.1 - 1.3e-21 76.8 0.0 2.3e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Mucin PF01456.17 EGF98342.1 - 0.094 12.7 8.0 0.2 11.7 8.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase PF00069.25 EGF98344.1 - 2.7e-36 125.3 0.0 5.9e-24 84.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF98344.1 - 1.3e-23 83.6 0.0 2e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF98344.1 - 5.7e-06 25.4 0.5 1.2e-05 24.3 0.5 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF98344.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pyr_redox_2 PF07992.14 EGF98345.1 - 1.6e-23 83.4 0.0 2.2e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGF98345.1 - 1.5e-07 31.9 0.1 1.4e-06 28.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGF98345.1 - 0.00016 21.0 0.1 0.018 14.2 0.1 2.5 1 1 2 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) DUF1690 PF07956.11 EGF98347.1 - 3.2e-13 50.3 0.2 3.6e-13 50.1 0.2 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) CHCH PF06747.13 EGF98347.1 - 0.019 15.1 0.2 0.031 14.4 0.2 1.4 1 0 0 1 1 1 0 CHCH domain Zn_clus PF00172.18 EGF98348.1 - 3.8e-05 23.7 2.8 5.3e-05 23.2 2.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1071 PF06378.11 EGF98348.1 - 0.21 11.2 2.0 0.3 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1071) Plant_tran PF04827.14 EGF98349.1 - 1.6e-37 129.1 0.0 2.1e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 EGF98349.1 - 7.2e-07 29.0 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGF98349.1 - 0.041 13.5 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DUF4148 PF13663.6 EGF98350.1 - 0.11 12.7 0.4 0.13 12.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) MBOAT_2 PF13813.6 EGF98351.1 - 3.4e-16 59.3 0.2 1.3e-15 57.4 0.2 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Dna2 PF08696.11 EGF98352.1 - 1.3e-48 165.5 0.0 2.7e-48 164.5 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 EGF98352.1 - 1.4e-35 122.8 0.0 2.8e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 EGF98352.1 - 0.00061 19.8 0.0 0.018 14.9 0.0 3.0 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Lact_bio_phlase PF09508.10 EGF98357.1 - 0.013 14.0 0.1 0.022 13.2 0.1 1.3 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase N-terminal TIM barrel domain Mg296 PF09644.10 EGF98357.1 - 0.072 13.2 1.4 0.089 12.9 0.1 1.7 2 0 0 2 2 2 0 Mg296 protein ATP_synt_H PF05493.13 EGF98359.1 - 1e-22 80.4 0.4 1.2e-22 80.1 0.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit H ARL6IP6 PF15062.6 EGF98359.1 - 0.0013 18.8 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Haemopoietic lineage transmembrane helix DUF4131 PF13567.6 EGF98359.1 - 0.097 12.3 0.6 0.12 12.1 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RecT PF03837.14 EGF98361.1 - 0.088 12.3 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 RecT family DUF5339 PF17274.2 EGF98361.1 - 0.11 13.4 0.5 0.49 11.3 0.1 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5339) CENP-B_dimeris PF09026.10 EGF98362.1 - 0.0085 16.5 0.2 0.0098 16.3 0.2 1.1 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Retrotran_gag_2 PF14223.6 EGF98363.1 - 6.1e-10 38.9 6.4 1.9e-09 37.3 0.1 2.7 2 1 1 3 3 3 2 gag-polypeptide of LTR copia-type DUF1447 PF07288.11 EGF98363.1 - 0.27 11.3 2.3 0.34 11.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) CPSase_L_D2 PF02786.17 EGF98365.1 - 2.5e-78 262.4 0.5 4.4e-78 261.6 0.5 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EGF98365.1 - 3.8e-71 239.0 0.0 7.3e-71 238.0 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EGF98365.1 - 3.2e-40 137.1 0.1 7.2e-40 136.0 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGF98365.1 - 4.7e-31 107.1 0.0 1.7e-30 105.3 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EGF98365.1 - 4.6e-27 95.2 0.0 1.2e-26 93.8 0.0 1.7 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EGF98365.1 - 2.1e-16 59.5 3.8 8.5e-16 57.6 3.5 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGF98365.1 - 1.6e-11 44.1 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EGF98365.1 - 2.7e-09 36.7 1.0 0.00013 21.7 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 EGF98365.1 - 6e-07 29.2 0.1 1.4e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGF98365.1 - 1.9e-05 24.8 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EGF98365.1 - 0.00015 22.5 0.4 0.82 10.4 0.1 2.9 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_4 PF13535.6 EGF98365.1 - 0.0002 21.0 0.0 0.00044 19.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EGF98365.1 - 0.0016 18.3 0.1 0.0035 17.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.11 EGF98365.1 - 0.0022 17.5 0.2 0.0043 16.5 0.2 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_D23 PF16576.5 EGF98365.1 - 0.0047 16.2 0.4 0.066 12.4 0.1 2.5 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 EGF98365.1 - 0.035 13.4 0.0 0.087 12.0 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 EGF98365.1 - 0.045 13.6 0.6 0.2 11.5 0.3 2.2 1 1 1 2 2 2 0 Glycine cleavage H-protein ATPgrasp_Ter PF15632.6 EGF98365.1 - 0.14 12.0 0.1 0.44 10.3 0.1 1.8 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon AA_permease PF00324.21 EGF98367.1 - 1.5e-144 482.2 43.6 1.9e-144 481.8 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGF98367.1 - 9e-33 113.7 47.2 1.3e-32 113.2 47.2 1.2 1 0 0 1 1 1 1 Amino acid permease Dimer_Tnp_hAT PF05699.14 EGF98369.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Zn_clus PF00172.18 EGF98370.1 - 3.8e-05 23.7 2.8 5.3e-05 23.2 2.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1071 PF06378.11 EGF98370.1 - 0.24 11.0 2.1 0.33 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1071) PIG-S PF10510.9 EGF98376.1 - 1.1e-11 44.3 0.2 1.2e-11 44.2 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein START PF01852.19 EGF98377.1 - 3.3e-07 29.9 0.0 6.8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 START domain PCNA_N PF00705.18 EGF98378.1 - 0.042 13.6 0.5 0.56 9.9 0.2 2.4 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain Abhydrolase_1 PF00561.20 EGF98379.1 - 0.0084 15.8 0.0 0.048 13.3 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_M3 PF01432.20 EGF98380.1 - 8.3e-127 424.2 0.5 1.1e-126 423.8 0.5 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EGF98380.1 - 0.081 12.5 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like GRAB PF10375.9 EGF98381.1 - 1.7e-06 27.7 0.1 6e-06 25.9 0.1 2.1 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GRIP PF01465.20 EGF98381.1 - 0.016 15.1 0.2 0.064 13.2 0.0 2.1 2 0 0 2 2 2 0 GRIP domain DASH_Hsk3 PF08227.11 EGF98381.1 - 2.3 8.7 7.8 3 8.3 1.0 3.3 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF4837 PF16125.5 EGF98381.1 - 3.1 6.7 16.2 0.42 9.6 10.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4837) Golgin_A5 PF09787.9 EGF98381.1 - 3.3 7.1 50.8 6.1 6.2 18.0 2.7 1 1 2 3 3 3 0 Golgin subfamily A member 5 Atg14 PF10186.9 EGF98381.1 - 7.9 5.5 42.5 1.1e+02 1.7 35.4 3.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Acyltransferase PF01553.21 EGF98384.1 - 0.0031 17.2 0.0 0.0066 16.1 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase DEAD PF00270.29 EGF98385.1 - 3e-48 163.9 0.0 1.9e-47 161.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF98385.1 - 7.3e-28 97.1 0.0 2.5e-27 95.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF98385.1 - 0.027 14.5 0.0 0.084 12.9 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EGF98385.1 - 0.075 12.3 0.0 0.26 10.5 0.0 1.8 1 1 0 1 1 1 0 SecA DEAD-like domain Arf PF00025.21 EGF98387.1 - 1.6e-57 193.8 0.0 1.7e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGF98387.1 - 2.8e-12 46.9 0.0 3.9e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGF98387.1 - 2.3e-11 43.6 0.0 2.6e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGF98387.1 - 2.7e-09 36.7 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGF98387.1 - 1.1e-08 34.7 0.1 1.7e-05 24.2 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EGF98387.1 - 8e-07 29.1 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGF98387.1 - 3.8e-05 23.2 0.0 4.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DNA_pol_A_exoN PF18305.1 EGF98387.1 - 0.0015 18.8 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 3' to 5' exonuclease C-terminal domain FeoB_N PF02421.18 EGF98387.1 - 0.0018 17.8 0.1 0.0048 16.4 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Laminin_II PF06009.12 EGF98391.1 - 0.082 12.9 3.6 4.6 7.3 0.6 2.3 1 1 1 2 2 2 0 Laminin Domain II CLZ PF16526.5 EGF98391.1 - 0.083 13.3 7.1 2 8.9 0.8 2.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Noelin-1 PF12308.8 EGF98391.1 - 0.11 12.5 3.7 0.05 13.6 1.0 1.8 2 0 0 2 2 2 0 Neurogenesis glycoprotein SlyX PF04102.12 EGF98391.1 - 0.16 12.6 7.2 0.057 14.0 1.6 2.7 2 1 1 3 3 3 0 SlyX KASH_CCD PF14662.6 EGF98391.1 - 0.18 11.6 9.6 5.3 6.8 9.6 2.2 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TMF_DNA_bd PF12329.8 EGF98391.1 - 0.18 11.8 0.1 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 EGF98391.1 - 0.61 10.1 3.3 4.1 7.5 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 EGF98391.1 - 0.73 10.3 4.1 3.7 8.1 4.1 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 Cep57_CLD_2 PF14197.6 EGF98391.1 - 1.9 8.6 8.0 7.5 6.7 7.0 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 EGF98391.1 - 3.5 7.8 5.3 5 7.3 0.8 2.3 2 0 0 2 2 2 0 bZIP transcription factor DASH_Hsk3 PF08227.11 EGF98392.1 - 0.15 12.4 0.5 0.41 11.0 0.5 1.7 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like Phage_int_SAM_4 PF13495.6 EGF98393.1 - 0.098 13.1 0.0 0.3 11.6 0.0 1.8 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Clat_adaptor_s PF01217.20 EGF98397.1 - 4.2e-19 68.9 0.2 3.4e-16 59.5 0.5 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 EGF98397.1 - 0.0035 17.4 0.2 0.0065 16.5 0.2 1.4 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 MOZART1 PF12554.8 EGF98400.1 - 3e-20 71.7 0.2 3.8e-20 71.4 0.2 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Glyoxal_oxid_N PF07250.11 EGF98402.1 - 5.4e-33 114.2 0.0 4.4e-31 107.9 0.0 3.4 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EGF98402.1 - 3.5e-22 78.5 0.1 8e-22 77.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 EGF98402.1 - 0.021 15.1 0.1 8.5 6.8 0.0 4.2 5 0 0 5 5 5 0 Kelch motif Kelch_4 PF13418.6 EGF98402.1 - 0.032 14.2 0.0 12 6.0 0.0 2.8 2 0 0 2 2 2 0 Galactose oxidase, central domain Aa_trans PF01490.18 EGF98403.1 - 4.5e-66 223.3 31.6 5e-66 223.1 31.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGF98403.1 - 0.00056 19.1 16.9 0.00056 19.1 16.9 2.3 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Pkinase PF00069.25 EGF98407.1 - 8.3e-56 189.3 0.0 9.8e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF98407.1 - 4.6e-35 121.2 0.0 5.7e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF98407.1 - 5.2e-07 29.3 0.0 4.2e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGF98407.1 - 0.00026 20.4 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF98407.1 - 0.0063 16.5 0.0 0.0097 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF98407.1 - 0.018 14.0 0.3 0.14 11.1 0.3 2.0 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EGF98407.1 - 0.091 12.4 0.1 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Prothymosin PF03247.14 EGF98409.1 - 3.9 8.0 9.9 11 6.6 9.9 1.7 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF3591 PF12157.8 EGF98411.1 - 6.1e-178 592.0 2.0 8.3e-178 591.6 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 EGF98411.1 - 0.0012 18.7 4.1 0.0028 17.4 4.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGF98411.1 - 0.064 13.4 1.8 0.11 12.7 1.8 1.3 1 0 0 1 1 1 0 Zinc knuckle TFIIF_beta PF02270.15 EGF98411.1 - 0.13 12.4 0.3 0.28 11.4 0.3 1.5 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain PGA2 PF07543.12 EGF98411.1 - 3.7 7.5 14.7 1.1 9.2 2.1 3.3 3 0 0 3 3 3 0 Protein trafficking PGA2 Ribosomal_L7Ae PF01248.26 EGF98413.1 - 8.8e-22 76.7 0.5 1.6e-21 75.9 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EGF98413.1 - 0.021 14.9 0.1 0.03 14.4 0.1 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 Lipase_GDSL PF00657.22 EGF98415.1 - 0.058 13.4 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Aminotran_1_2 PF00155.21 EGF98418.1 - 2.5e-36 125.6 0.0 3.2e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGF98418.1 - 0.0016 17.8 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EGF98418.1 - 0.017 13.7 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme tRNA-synt_1b PF00579.25 EGF98418.1 - 0.11 11.8 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) MCM PF00493.23 EGF98419.1 - 9.8e-84 279.9 0.2 2.1e-82 275.6 0.2 2.5 1 1 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGF98419.1 - 1.3e-37 128.5 0.0 2.6e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGF98419.1 - 7.7e-27 93.5 1.3 2e-26 92.2 1.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 EGF98419.1 - 5.9e-20 72.1 19.7 5.9e-20 72.1 19.7 2.3 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 EGF98419.1 - 6.8e-11 42.7 0.0 2.3e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGF98419.1 - 5.3e-07 29.2 0.0 1.4e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGF98419.1 - 0.00014 21.7 0.0 0.05 13.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF445 PF04286.12 EGF98419.1 - 0.022 14.6 2.7 1.2 8.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF445) zinc_ribbon_2 PF13240.6 EGF98419.1 - 4.6 7.1 5.1 29 4.6 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbon domain PHM7_cyt PF14703.6 EGF98421.1 - 0.0064 16.7 0.7 0.014 15.7 0.7 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter K-box PF01486.17 EGF98421.1 - 0.028 14.6 0.5 0.083 13.1 0.5 1.8 1 0 0 1 1 1 0 K-box region BRICHOS PF04089.14 EGF98421.1 - 0.051 13.8 1.1 0.15 12.3 0.6 2.1 1 1 0 1 1 1 0 BRICHOS domain TMEM237 PF15383.6 EGF98421.1 - 0.08 12.0 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 WBS_methylT PF12589.8 EGF98422.1 - 7.1e-21 74.8 8.1 1.2e-20 74.1 8.1 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EGF98422.1 - 1.1e-08 35.6 0.0 2.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF98422.1 - 2.4e-08 34.5 0.1 7.5e-08 33.0 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF98422.1 - 4.6e-05 24.1 0.1 0.00014 22.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF98422.1 - 0.00048 20.0 0.0 0.0006 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EGF98422.1 - 0.0014 18.9 0.0 0.0046 17.3 0.0 1.8 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 EGF98422.1 - 0.0021 17.9 0.2 0.0034 17.2 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGF98422.1 - 0.018 15.0 0.6 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain N6_N4_Mtase PF01555.18 EGF98422.1 - 0.067 12.9 2.2 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 DNA methylase CxC1 PF18802.1 EGF98425.1 - 0.00088 19.4 0.1 0.0017 18.5 0.1 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGF98425.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase DUF4419 PF14388.6 EGF98426.1 - 0.0097 15.4 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF313 PF03754.13 EGF98426.1 - 0.21 11.8 2.6 1.5 9.1 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF313) PTPRCAP PF15713.5 EGF98427.1 - 0.067 13.5 1.0 8.5 6.7 0.4 2.3 1 1 1 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Catalase PF00199.19 EGF98428.1 - 2e-169 563.7 1.1 2.6e-169 563.3 1.1 1.1 1 0 0 1 1 1 1 Catalase zf-MYND PF01753.18 EGF98429.1 - 3.3e-10 39.9 6.5 3.3e-10 39.9 6.5 2.0 2 1 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 EGF98429.1 - 7.1 7.0 7.5 1.1 9.6 3.1 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Herpes_UL25 PF01499.16 EGF98431.1 - 0.002 16.7 0.0 0.0026 16.3 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL25 family Methyltransf_16 PF10294.9 EGF98431.1 - 0.0066 16.2 0.0 0.19 11.4 0.0 2.3 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EGF98431.1 - 0.31 11.8 2.9 1.1 10.0 0.0 3.1 3 1 0 3 3 3 0 Methyltransferase domain Rad60-SLD PF11976.8 EGF98432.1 - 3.9e-21 74.7 0.8 6.3e-21 74.0 0.4 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGF98432.1 - 2.3e-11 43.3 0.0 3.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Imm6 PF14434.6 EGF98432.1 - 0.12 12.3 0.1 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Immunity protein Imm6 Y1_Tnp PF01797.16 EGF98432.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Transposase IS200 like Rad60-SLD PF11976.8 EGF98433.1 - 4.8e-11 42.3 0.0 5.9e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGF98433.1 - 0.00011 21.9 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Glyco_hydro_65C PF03633.15 EGF98433.1 - 0.16 11.9 0.1 22 5.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, C-terminal domain CxC5 PF18718.1 EGF98434.1 - 1.3e-22 80.0 8.0 4.2e-22 78.4 8.0 1.9 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGF98434.1 - 8.4e-18 64.4 0.3 8.4e-18 64.4 0.3 2.5 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 EGF98434.1 - 0.0088 15.9 1.3 0.0088 15.9 1.3 2.2 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases Alpha_kinase PF02816.18 EGF98435.1 - 7.1e-10 39.3 0.4 9.5e-10 38.9 0.4 1.1 1 0 0 1 1 1 1 Alpha-kinase family Rad60-SLD PF11976.8 EGF98437.1 - 1.7e-07 31.0 0.3 5.2e-07 29.4 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PepSY_like PF11396.8 EGF98438.1 - 0.085 13.4 0.7 0.2 12.2 0.3 1.9 1 1 1 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like PNK3P PF08645.11 EGF98438.1 - 0.17 11.6 0.7 0.21 11.3 0.7 1.3 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Adipogenin PF15202.6 EGF98439.1 - 0.049 13.7 1.3 0.075 13.1 1.3 1.2 1 0 0 1 1 1 0 Adipogenin DUF3906 PF13046.6 EGF98442.1 - 0.15 12.2 2.4 8.7 6.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) CAF-1_p150 PF11600.8 EGF98442.1 - 0.23 11.2 25.8 0.34 10.6 25.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PorB PF11565.8 EGF98442.1 - 0.29 11.6 4.4 6.1 7.3 0.1 2.3 1 1 1 2 2 2 0 Alpha helical Porin B Nmad3 PF18754.1 EGF98443.1 - 0.053 13.1 1.7 0.07 12.7 0.1 1.9 2 0 0 2 2 2 0 Nucleotide modification associated domain 3 ATP-gua_PtransN PF02807.15 EGF98444.1 - 0.00054 20.3 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain SPX PF03105.19 EGF98445.1 - 4.8e-31 109.0 7.2 1.2e-19 71.6 0.9 2.7 1 1 1 2 2 2 2 SPX domain zf-C3HC4_4 PF15227.6 EGF98445.1 - 1.3e-09 38.1 11.2 2.7e-09 37.0 11.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EGF98445.1 - 6.2e-08 32.4 9.2 1.3e-07 31.4 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF98445.1 - 1e-07 31.7 8.9 2e-07 30.7 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF98445.1 - 1.4e-07 31.7 9.3 1.4e-07 31.7 9.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGF98445.1 - 2.8e-07 30.3 13.0 4.8e-07 29.5 13.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF98445.1 - 9.7e-07 28.7 2.5 9.7e-07 28.7 2.5 2.5 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGF98445.1 - 9.2e-06 25.5 10.1 4.8e-05 23.2 10.4 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 EGF98445.1 - 0.00031 20.4 10.2 0.0012 18.6 7.0 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EGF98445.1 - 0.0013 18.6 11.9 0.0085 15.9 12.2 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGF98445.1 - 0.081 13.2 9.8 0.088 13.1 7.6 2.2 2 1 0 2 2 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGF98445.1 - 0.11 12.5 7.7 0.2 11.7 5.7 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EGF98445.1 - 0.6 10.3 8.5 1.6 9.0 8.5 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn-ribbon_8 PF09723.10 EGF98445.1 - 2.2 8.5 7.6 4.3 7.5 4.9 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS91 PF14319.6 EGF98445.1 - 3.2 7.8 7.7 13 5.9 7.7 2.1 1 1 0 1 1 1 0 Transposase zinc-binding domain Cnd1 PF12717.7 EGF98446.1 - 0.00021 21.3 2.7 0.51 10.4 0.1 3.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGF98446.1 - 0.00024 21.4 2.3 0.87 10.0 0.0 5.7 5 1 1 6 6 6 1 HEAT repeats HEAT PF02985.22 EGF98446.1 - 0.00031 20.7 2.1 21 5.7 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 EGF98446.1 - 0.00063 20.2 1.3 0.39 11.3 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat CENP-X PF09415.10 EGF98446.1 - 0.0083 16.4 0.8 22 5.5 0.0 4.1 3 0 0 3 3 3 2 CENP-S associating Centromere protein X KIX_2 PF16987.5 EGF98447.1 - 0.0061 16.5 1.2 0.041 13.9 1.0 2.4 1 1 1 2 2 2 1 KIX domain DUF421 PF04239.12 EGF98447.1 - 0.012 15.4 1.7 0.22 11.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF421) DUF1062 PF06353.12 EGF98448.1 - 0.023 15.5 0.1 0.039 14.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) zf-C2H2_jaz PF12171.8 EGF98448.1 - 0.059 13.7 0.8 0.059 13.7 0.8 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 EGF98448.1 - 2.7 8.0 5.7 17 5.4 5.7 2.0 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Pannexin_like PF12534.8 EGF98449.1 - 0.03 13.4 0.6 0.051 12.6 0.6 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Phage_TTP_11 PF16460.5 EGF98451.1 - 0.057 13.3 0.0 0.097 12.5 0.0 1.4 1 1 0 1 1 1 0 Phage tail tube, TTP, lambda-like GIY-YIG PF01541.24 EGF98452.1 - 3.5e-13 49.6 0.1 6.9e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain GLE1 PF07817.13 EGF98452.1 - 0.089 12.0 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 GLE1-like protein FANCL_C PF11793.8 EGF98452.1 - 0.26 11.5 1.5 1.3 9.3 0.1 2.5 3 0 0 3 3 3 0 FANCL C-terminal domain zf-RING-like PF08746.11 EGF98452.1 - 1.4 9.3 4.9 0.4 11.0 0.4 2.1 2 0 0 2 2 2 0 RING-like domain Herpes_Helicase PF02689.14 EGF98455.1 - 9.6e-08 30.4 0.1 1.1e-07 30.3 0.1 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 EGF98455.1 - 0.00061 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EGF98455.1 - 0.034 13.9 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TRM PF02005.16 EGF98457.1 - 1.2e-118 396.6 0.0 1.5e-118 396.2 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Rubredoxin_2 PF18073.1 EGF98457.1 - 0.018 14.7 1.2 0.018 14.7 1.2 2.6 2 0 0 2 2 2 0 Rubredoxin metal binding domain RhoGAP PF00620.27 EGF98458.1 - 6e-13 48.9 0.1 5.5e-12 45.8 0.0 2.0 1 1 1 2 2 2 1 RhoGAP domain HNOB PF07700.15 EGF98458.1 - 0.12 12.3 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Haem-NO-binding CxC1 PF18802.1 EGF98459.1 - 8.5e-27 93.3 0.0 1.8e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF98459.1 - 1.3e-06 28.5 0.0 2.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGF98459.1 - 8.8e-06 25.5 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC3 PF18804.1 EGF98459.1 - 0.0028 17.5 0.1 0.073 12.9 0.0 2.7 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases SNF2_N PF00176.23 EGF98460.1 - 3.2e-07 29.4 0.3 8.3e-07 28.0 0.3 1.5 1 1 1 2 2 2 1 SNF2 family N-terminal domain KDZ PF18758.1 EGF98461.1 - 1.2e-09 38.1 0.0 3.6e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase MCM6_C PF18263.1 EGF98463.1 - 0.083 13.1 0.0 0.09 13.0 0.0 1.1 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain DEAD PF00270.29 EGF98464.1 - 1.1e-47 162.1 0.0 3.6e-47 160.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF98464.1 - 4.1e-31 107.6 0.0 1.7e-29 102.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGF98464.1 - 2.2e-05 23.8 0.0 3.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EGF98464.1 - 0.00076 19.5 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGF98464.1 - 0.027 13.8 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 EGF98464.1 - 0.028 14.7 0.0 0.072 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain CS PF04969.16 EGF98465.1 - 1.2e-18 67.9 1.5 1.2e-18 67.9 1.5 1.7 2 0 0 2 2 2 1 CS domain Ribosomal_S11 PF00411.19 EGF98466.1 - 0.028 14.8 3.9 1.8 9.0 0.1 2.8 2 1 1 3 3 3 0 Ribosomal protein S11 Peptidase_A2E PF12382.8 EGF98466.1 - 0.08 13.0 0.0 0.27 11.2 0.0 1.8 1 1 1 2 2 2 0 Retrotransposon peptidase DUF648 PF04890.13 EGF98467.1 - 0.36 10.5 5.6 0.21 11.3 2.5 1.7 1 1 0 2 2 2 0 Family of unknown function (DUF648) SNF2_N PF00176.23 EGF98470.1 - 8.4e-44 149.7 1.0 9.4e-44 149.5 1.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGF98470.1 - 2.2e-07 31.1 0.0 2.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGF98470.1 - 5.5e-07 29.5 0.0 6.6e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGF98470.1 - 0.00079 19.2 0.0 0.00098 18.8 0.0 1.3 1 1 0 1 1 1 1 SWI2/SNF2 ATPase Helicase_C PF00271.31 EGF98471.1 - 4.8e-15 55.9 0.0 7.9e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PPDK_N PF01326.19 EGF98471.1 - 0.084 12.1 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain SWIB PF02201.18 EGF98474.1 - 1.8e-19 69.4 0.0 3.4e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Tektin PF03148.14 EGF98474.1 - 0.029 13.1 0.6 0.03 13.1 0.6 1.1 1 0 0 1 1 1 0 Tektin family bZIP_1 PF00170.21 EGF98475.1 - 5.8e-08 32.7 11.0 5.8e-08 32.7 11.0 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGF98475.1 - 0.0025 17.9 11.4 0.0025 17.9 11.4 2.0 2 0 0 2 2 2 1 Basic region leucine zipper Taxilin PF09728.9 EGF98475.1 - 0.0035 16.6 7.8 0.006 15.8 7.8 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TSC22 PF01166.18 EGF98475.1 - 0.035 14.4 3.2 0.091 13.1 3.2 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family NRBF2 PF08961.10 EGF98475.1 - 0.044 13.4 2.9 0.079 12.5 2.9 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator CENP-H PF05837.12 EGF98475.1 - 0.091 13.2 5.6 0.16 12.3 5.6 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.12 EGF98475.1 - 0.13 12.8 8.1 0.15 12.5 6.6 1.9 1 1 1 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 EGF98475.1 - 0.44 10.4 3.1 1.1 9.0 3.1 1.7 1 0 0 1 1 1 0 Septum formation initiator LRR_4 PF12799.7 EGF98476.1 - 3.3 8.3 6.3 6.2 7.4 0.1 3.8 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) RXT2_N PF08595.11 EGF98479.1 - 0.067 13.2 1.4 0.12 12.4 1.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Glyco_hydro_79C PF16862.5 EGF98481.1 - 7.3e-14 52.5 0.0 1.1e-13 51.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Sars6 PF12133.8 EGF98481.1 - 0.17 11.8 0.1 19 5.3 0.0 2.3 2 0 0 2 2 2 0 Open reading frame 6 from SARS coronavirus SET PF00856.28 EGF98483.1 - 7.7e-06 26.4 0.0 1.8e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 SET domain zf-C2H2_aberr PF17017.5 EGF98484.1 - 6e-07 29.8 2.8 0.0091 16.2 0.0 2.9 2 1 1 3 3 3 2 Aberrant zinc-finger Voltage_CLC PF00654.20 EGF98484.1 - 0.012 14.8 0.7 0.016 14.5 0.7 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel zf-C2H2_4 PF13894.6 EGF98484.1 - 0.035 15.0 1.6 9.6 7.4 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGF98484.1 - 0.092 13.2 0.7 3.5 8.3 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Dynamin_M PF01031.20 EGF98485.1 - 1.5e-100 336.1 0.0 2.3e-100 335.5 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EGF98485.1 - 4.5e-54 183.0 0.0 7.6e-54 182.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EGF98485.1 - 4.5e-28 97.3 2.6 4.5e-28 97.3 2.6 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGF98485.1 - 0.0002 21.4 0.2 0.001 19.1 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EGF98485.1 - 0.0088 15.8 1.4 3 7.4 0.3 2.3 2 0 0 2 2 2 2 AAA ATPase domain PTPA PF03095.15 EGF98486.1 - 1.1e-93 314.0 0.2 1.3e-93 313.8 0.2 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Spin-Ssty PF02513.17 EGF98486.1 - 0.0018 18.0 2.0 0.0053 16.4 2.0 1.8 1 0 0 1 1 1 1 Spin/Ssty Family AAA PF00004.29 EGF98487.1 - 4.8e-41 140.3 0.0 9.9e-41 139.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF98487.1 - 4.5e-08 32.8 0.1 1.1e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGF98487.1 - 8.3e-06 26.0 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGF98487.1 - 2.2e-05 24.5 0.1 0.00012 22.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGF98487.1 - 0.0002 21.6 0.0 0.0066 16.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 EGF98487.1 - 0.00048 19.4 0.0 0.00087 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EGF98487.1 - 0.00057 20.3 0.3 0.01 16.2 0.0 2.4 2 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 EGF98487.1 - 0.0031 17.3 0.0 0.0075 16.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGF98487.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGF98487.1 - 0.014 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGF98487.1 - 0.016 14.8 0.0 0.035 13.6 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGF98487.1 - 0.03 14.7 0.0 0.076 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EGF98487.1 - 0.048 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGF98487.1 - 0.05 13.3 0.1 0.12 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGF98487.1 - 0.054 13.4 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGF98487.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGF98487.1 - 0.1 12.0 0.7 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGF98487.1 - 0.11 12.1 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGF98487.1 - 0.14 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Retrotran_gag_2 PF14223.6 EGF98488.1 - 5.2e-13 48.8 0.2 7.7e-13 48.3 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGF98488.1 - 0.0094 15.6 0.2 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) DUF3150 PF11348.8 EGF98488.1 - 0.11 11.7 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Rhomboid_SP PF12595.8 EGF98490.1 - 0.017 14.5 2.2 0.055 12.8 0.0 2.0 1 1 0 2 2 2 0 Rhomboid serine protease Rhomboid_SP PF12595.8 EGF98491.1 - 0.021 14.2 2.5 0.055 12.8 0.1 2.0 1 1 0 2 2 2 0 Rhomboid serine protease LMBR1 PF04791.16 EGF98492.1 - 1.6 7.6 3.1 2 7.2 0.9 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein TAP42 PF04177.12 EGF98493.1 - 7.2e-80 268.5 7.9 8.3e-80 268.3 7.9 1.0 1 0 0 1 1 1 1 TAP42-like family Adaptin_N PF01602.20 EGF98494.1 - 9.5e-79 265.3 2.4 1.5e-57 195.4 0.9 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EGF98494.1 - 4.9e-18 65.4 1.2 8.6e-18 64.7 0.1 2.0 3 0 0 3 3 3 1 Adaptin C-terminal domain Cnd1 PF12717.7 EGF98494.1 - 9.2e-05 22.5 6.1 0.00058 19.9 0.6 3.4 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 tRNA-synt_1e PF01406.19 EGF98497.1 - 5.1e-123 410.2 0.3 5.1e-123 410.2 0.3 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGF98497.1 - 4.2e-06 25.8 4.9 0.0005 18.9 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGF98497.1 - 0.00047 18.5 0.0 0.007 14.7 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 EGF98497.1 - 0.0041 16.1 0.0 0.0041 16.1 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain Retrotran_gag_2 PF14223.6 EGF98498.1 - 3.1e-09 36.6 0.1 6.1e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGF98498.1 - 4.3e-06 26.2 0.0 1.2e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_2 PF14223.6 EGF98500.1 - 7.7e-12 45.1 0.5 1.2e-11 44.4 0.5 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EGF98500.1 - 0.00042 19.9 0.2 0.0011 18.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 EGF98500.1 - 0.12 12.2 0.1 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type FRG1 PF06229.12 EGF98503.1 - 6e-17 62.0 1.6 1.1e-14 54.7 1.6 2.6 1 1 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 EGF98503.1 - 0.0011 19.2 0.0 0.03 14.6 0.0 2.4 2 0 0 2 2 2 1 Fascin domain DHquinase_II PF01220.19 EGF98504.1 - 0.0019 17.9 0.4 18 5.0 0.0 3.5 3 0 0 3 3 3 1 Dehydroquinase class II Nudix_N PF12535.8 EGF98504.1 - 0.0065 16.1 0.0 35 4.1 0.0 3.3 3 0 0 3 3 3 0 Hydrolase of X-linked nucleoside diphosphate N terminal PXT1 PF15214.6 EGF98504.1 - 0.0094 16.3 5.1 2.5 8.5 0.2 4.1 4 0 0 4 4 4 1 Peroxisomal testis-specific protein 1 HTH_55 PF18622.1 EGF98504.1 - 0.011 16.0 0.1 73 3.7 0.0 3.7 3 0 0 3 3 3 0 RctB helix turn helix domain DUF5374 PF17344.2 EGF98504.1 - 0.13 12.2 1.4 88 3.1 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5374) Keratin_2_head PF16208.5 EGF98504.1 - 0.18 12.0 109.5 0.095 12.8 24.3 4.8 4 0 0 4 4 4 0 Keratin type II head MspA PF09203.11 EGF98504.1 - 0.22 11.3 51.1 0.37 10.6 7.4 4.7 4 0 0 4 4 4 0 MspA Rota_NS26 PF01525.16 EGF98504.1 - 0.54 10.2 2.2 34 4.3 0.1 2.9 3 0 0 3 3 3 0 Rotavirus NS26 MrpF_PhaF PF04066.13 EGF98504.1 - 6.3 7.3 10.9 1.5e+02 2.9 0.1 4.8 4 0 0 4 4 4 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) DUF2964 PF11177.8 EGF98504.1 - 7.9 6.8 24.8 2.5 8.4 0.3 6.2 7 0 0 7 7 7 0 Protein of unknown function (DUF2964) UQ_con PF00179.26 EGF98505.1 - 0.003 17.2 0.2 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Beta-TrCP_D PF12125.8 EGF98505.1 - 0.12 12.3 0.6 0.27 11.2 0.6 1.5 1 0 0 1 1 1 0 D domain of beta-TrCP CRT10 PF08728.10 EGF98507.1 - 0.7 8.0 4.1 1 7.4 4.1 1.1 1 0 0 1 1 1 0 CRT10 Med19 PF10278.9 EGF98507.1 - 2.2 8.2 6.7 28 4.6 6.1 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Helicase_C PF00271.31 EGF98510.1 - 0.027 14.8 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DnaJ PF00226.31 EGF98512.1 - 9.3e-18 64.1 0.6 2.5e-17 62.7 0.0 2.0 2 1 0 2 2 2 1 DnaJ domain Helicase_C PF00271.31 EGF98516.1 - 3.7e-11 43.4 0.0 6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGF98516.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.2 1 1 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Ligase_CoA PF00549.19 EGF98516.1 - 0.16 11.8 0.2 0.59 9.9 0.2 1.8 1 1 0 1 1 1 0 CoA-ligase Glyco_hydro_12 PF01670.16 EGF98517.1 - 5.1e-17 62.6 2.8 6.1e-17 62.3 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 UCR_UQCRX_QCR9 PF05365.12 EGF98518.1 - 9.6e-27 92.7 2.8 1.1e-26 92.5 2.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like MIP PF00230.20 EGF98519.1 - 4.5e-06 26.5 1.1 5.5e-06 26.3 1.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2415 PF10313.9 EGF98521.1 - 1.5e-11 44.0 0.0 6e-11 42.1 0.0 2.2 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Ran-binding PF05508.11 EGF98521.1 - 0.066 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 RanGTP-binding protein MBOAT_2 PF13813.6 EGF98523.1 - 9.5e-15 54.6 4.3 2.6e-14 53.2 4.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF3788 PF12663.7 EGF98523.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) Peptidase_C65 PF10275.9 EGF98526.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain FAR1 PF03101.15 EGF98526.1 - 0.054 14.2 0.1 0.13 12.9 0.1 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain tRNA-synt_1g PF09334.11 EGF98527.1 - 2.2e-151 504.1 0.7 2.8e-151 503.7 0.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 EGF98527.1 - 4.9e-06 26.6 0.3 1.2e-05 25.4 0.3 1.6 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 EGF98527.1 - 0.00049 18.5 1.8 0.054 11.7 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGF98527.1 - 0.001 19.1 0.0 0.0031 17.5 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA KAR9 PF08580.10 EGF98527.1 - 0.012 14.2 0.5 0.035 12.7 0.0 1.8 2 0 0 2 2 2 0 Yeast cortical protein KAR9 AAA_18 PF13238.6 EGF98527.1 - 0.099 13.2 0.2 2.7 8.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain RNase_HII PF01351.18 EGF98528.1 - 7.6e-52 176.0 0.0 5.1e-44 150.5 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease HII AsiA PF09010.10 EGF98528.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Anti-Sigma Factor A zf-RING_2 PF13639.6 EGF98530.1 - 2e-11 44.0 8.7 4.3e-11 43.0 8.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGF98530.1 - 2.2e-06 27.3 4.0 4.2e-06 26.4 4.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EGF98530.1 - 1.7e-05 25.0 4.9 4.8e-05 23.6 4.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGF98530.1 - 0.00029 20.7 4.8 0.00064 19.5 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF98530.1 - 0.00067 19.4 7.8 0.0016 18.3 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGF98530.1 - 0.00081 19.4 2.0 0.0014 18.6 2.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGF98530.1 - 0.0019 18.1 3.7 0.0038 17.1 3.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 EGF98530.1 - 0.0032 17.6 3.8 0.0073 16.5 3.8 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.6 EGF98530.1 - 0.026 14.3 8.9 0.047 13.5 8.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EGF98530.1 - 0.14 12.0 7.6 0.63 9.9 4.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGF98530.1 - 0.15 12.0 4.0 0.28 11.1 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF98530.1 - 0.16 12.1 6.3 0.4 10.7 6.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.7 EGF98530.1 - 0.31 11.2 4.5 0.59 10.3 4.5 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 EGF98530.1 - 2.5 8.0 6.2 5.2 7.1 6.2 1.6 1 0 0 1 1 1 0 PHD-finger Sec20 PF03908.13 EGF98531.1 - 4.7e-20 71.3 4.8 1.1e-19 70.1 4.8 1.7 1 0 0 1 1 1 1 Sec20 MRP-S31 PF15433.6 EGF98531.1 - 0.89 9.2 6.7 1.5 8.5 6.7 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 CP12 PF02672.15 EGF98531.1 - 1.3 9.8 5.4 0.62 10.9 0.1 2.9 3 0 0 3 3 3 0 CP12 domain Kinesin_assoc PF16183.5 EGF98531.1 - 4.5 7.4 6.2 2.6 8.2 3.8 1.8 2 0 0 2 2 2 0 Kinesin-associated Mito_carr PF00153.27 EGF98532.1 - 4.7e-22 77.7 1.4 5.9e-12 45.3 0.0 3.3 4 0 0 4 4 4 2 Mitochondrial carrier protein Serine_protease PF18405.1 EGF98532.1 - 0.038 13.1 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Gammaproteobacterial serine protease Apt1 PF10351.9 EGF98534.1 - 8.4 5.1 17.6 8.5 5.1 17.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DHC_N1 PF08385.12 EGF98536.1 - 1.7e-104 350.5 3.2 6e-103 345.4 0.7 3.2 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EGF98536.1 - 4.5e-57 193.5 1.5 1.6e-37 129.2 0.0 3.0 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region Response_reg PF00072.24 EGF98536.1 - 0.0059 16.8 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Occludin_ELL PF07303.13 EGF98536.1 - 1 10.1 5.7 0.65 10.8 0.6 3.3 3 0 0 3 3 3 0 Occludin homology domain DUF3195 PF11424.8 EGF98537.1 - 0.1 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGF98537.1 - 0.15 11.0 0.4 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 NUC194 domain DUF2170 PF09938.9 EGF98537.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) Retrotran_gag_2 PF14223.6 EGF98542.1 - 5.1e-09 35.9 0.6 8.1e-09 35.3 0.1 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type PI3K_1B_p101 PF10486.9 EGF98542.1 - 0.0063 14.4 0.8 0.011 13.6 0.8 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MBR1 PF17058.5 EGF98542.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial biogenesis regulation protein 1 Glyco_hydro_14 PF01373.17 EGF98544.1 - 0.21 10.5 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 Acyl_transf_1 PF00698.21 EGF98545.1 - 5.8e-53 180.4 0.0 9.3e-35 120.6 0.0 2.6 1 1 1 2 2 2 2 Acyl transferase domain Fas_alpha_ACP PF18325.1 EGF98545.1 - 3.5e-40 138.0 0.0 6.9e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain MaoC_dehydratas PF01575.19 EGF98545.1 - 8.1e-20 70.6 0.0 5.5e-19 67.9 0.0 2.3 3 0 0 3 3 3 1 MaoC like domain FAS_I_H PF18314.1 EGF98545.1 - 3.2e-11 43.3 0.0 6.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain FAS_meander PF17951.1 EGF98545.1 - 2.3e-09 37.2 0.0 7.7e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain Rbsn PF11464.8 EGF98545.1 - 8.9e-06 25.3 0.6 8.9e-06 25.3 0.6 2.1 2 0 0 2 2 2 1 Rabenosyn Rab binding domain MaoC_dehydrat_N PF13452.6 EGF98545.1 - 0.021 14.9 0.5 0.97 9.6 0.5 2.5 1 1 0 1 1 1 0 N-terminal half of MaoC dehydratase Mo25 PF08569.11 EGF98546.1 - 6.2e-18 65.2 5.6 3.5e-15 56.2 2.5 2.0 1 1 1 2 2 2 2 Mo25-like VHS PF00790.19 EGF98547.1 - 6.7e-24 84.4 0.8 2.5e-23 82.5 0.0 2.0 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 EGF98547.1 - 3.7e-15 55.8 7.1 6.8e-15 55.0 7.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EGF98547.1 - 5.2e-06 26.0 9.9 0.00049 19.8 3.7 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 EGF98547.1 - 0.055 13.8 0.0 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 GAT domain Transcrip_reg PF01709.20 EGF98547.1 - 0.31 10.4 0.3 2.7 7.3 0.0 2.3 3 0 0 3 3 3 0 Transcriptional regulator C1_1 PF00130.22 EGF98547.1 - 0.33 10.9 4.1 0.3 11.0 2.5 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.11 EGF98547.1 - 0.54 10.2 3.4 1.2 9.1 3.4 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DZR PF12773.7 EGF98547.1 - 1.4 9.0 7.9 11 6.2 7.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_9 PF13901.6 EGF98547.1 - 1.8 8.5 5.0 3.7 7.5 5.0 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon C1_2 PF03107.16 EGF98547.1 - 5.2 7.5 6.5 2.2 8.6 3.0 2.1 2 0 0 2 2 2 0 C1 domain Urb2 PF10441.9 EGF98549.1 - 2.2e-18 66.9 0.0 2.2e-18 66.9 0.0 4.5 4 3 2 6 6 6 2 Urb2/Npa2 family AAA_lid_7 PF17867.1 EGF98549.1 - 0.019 15.1 0.0 0.53 10.5 0.0 3.3 2 0 0 2 2 2 0 Midasin AAA lid domain Homeodomain PF00046.29 EGF98550.1 - 0.00015 21.6 1.3 0.00036 20.3 1.3 1.7 1 0 0 1 1 1 1 Homeodomain DOCK_N PF16172.5 EGF98551.1 - 2.8e-88 296.4 0.0 2.9e-60 204.2 0.0 3.0 2 1 0 2 2 2 2 DOCK N-terminus DHR-2 PF06920.13 EGF98551.1 - 2.1e-59 201.6 5.0 1.2e-49 169.4 7.6 3.2 1 1 1 2 2 2 2 Dock homology region 2 DOCK-C2 PF14429.6 EGF98551.1 - 8.5e-50 169.3 0.0 1.7e-49 168.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins RNA_pol_Rpb1_1 PF04997.12 EGF98552.1 - 3.9e-105 351.6 0.0 6.4e-105 350.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EGF98552.1 - 3e-104 348.2 0.0 4.1e-104 347.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGF98552.1 - 7.5e-74 247.5 0.0 1.2e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EGF98552.1 - 7.4e-64 215.1 0.0 1.3e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EGF98552.1 - 2.8e-50 170.3 0.0 5.6e-50 169.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EGF98552.1 - 4.9e-48 162.6 2.5 9.4e-48 161.6 2.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EGF98552.1 - 1.5e-38 131.0 0.2 3.3e-38 129.9 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EGF98552.1 - 2.9e-16 58.9 180.0 0.022 15.1 6.5 13.3 10 2 2 13 13 13 12 RNA polymerase Rpb1 C-terminal repeat Pyr_redox_2 PF07992.14 EGF98553.1 - 1.4e-22 80.3 0.0 5.4e-20 71.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGF98553.1 - 7.7e-09 36.0 0.0 1e-07 32.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGF98553.1 - 0.0011 18.3 0.1 0.0089 15.3 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGF98553.1 - 0.0017 18.3 0.1 2.6 8.0 0.0 3.5 3 1 1 4 4 4 2 FAD-NAD(P)-binding Serpin PF00079.20 EGF98553.1 - 0.025 13.9 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) LSM PF01423.22 EGF98554.1 - 7e-15 54.5 0.3 1.6e-14 53.3 0.3 1.7 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGF98554.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 EGF98554.1 - 0.083 13.0 0.1 0.67 10.1 0.0 2.3 2 1 0 2 2 2 0 RimP C-terminal SH3 domain DMA PF03474.14 EGF98556.1 - 0.15 11.6 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 DMRTA motif CxC1 PF18802.1 EGF98558.1 - 1.3e-10 41.4 0.1 2.4e-07 30.8 0.0 2.5 1 1 1 2 2 2 2 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF98558.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases RhoGEF PF00621.20 EGF98559.1 - 7e-25 88.3 0.3 7e-25 88.3 0.3 2.8 3 0 0 3 3 3 1 RhoGEF domain Staph_opine_DH PF10100.9 EGF98559.1 - 0.021 13.5 0.1 0.044 12.4 0.1 1.4 1 0 0 1 1 1 0 Staphylopine dehydrogenase APG17 PF04108.12 EGF98559.1 - 0.18 10.8 11.2 0.039 13.1 2.3 2.8 2 1 0 2 2 2 0 Autophagy protein Apg17 Rol_Rep_N PF18106.1 EGF98559.1 - 0.92 9.9 3.3 1.7e+02 2.6 0.0 3.7 4 0 0 4 4 4 0 Rolling Circle replication initiation protein N-terminal domain OmpH PF03938.14 EGF98559.1 - 1.4 9.2 4.5 5.2 7.4 4.5 2.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HGTP_anticodon PF03129.20 EGF98559.1 - 2.9 8.1 5.8 0.99 9.6 2.3 2.1 2 0 0 2 2 2 0 Anticodon binding domain Ferric_reduct PF01794.19 EGF98560.1 - 9.6e-18 64.5 10.8 9.6e-18 64.5 10.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGF98560.1 - 5.4e-09 36.4 0.2 8.3e-08 32.5 0.2 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGF98560.1 - 0.0063 16.6 0.0 0.033 14.3 0.0 2.2 2 1 0 2 2 2 1 FAD-binding domain DUF2615 PF11027.8 EGF98560.1 - 0.86 9.8 1.9 4.7 7.4 0.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2615) Orf78 PF06024.12 EGF98560.1 - 2.7 8.4 0.0 2.7 8.4 0.0 2.9 3 0 0 3 3 3 0 Orf78 (ac78) DUF2244 PF10003.9 EGF98560.1 - 6.8 6.4 8.4 0.59 9.8 0.6 2.4 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4470 PF14737.6 EGF98561.1 - 6.8e-13 48.6 0.0 2e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 EGF98561.1 - 0.00012 21.7 0.2 0.00032 20.3 0.2 1.8 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EGF98561.1 - 0.00024 21.0 3.3 0.00057 19.8 1.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGF98561.1 - 0.0022 17.7 0.5 0.0022 17.7 0.5 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGF98561.1 - 0.023 15.0 1.0 6.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF98561.1 - 0.28 11.3 1.4 13 6.1 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat NAD_binding_6 PF08030.12 EGF98562.1 - 7.5e-15 55.4 0.1 1.3e-13 51.4 0.1 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGF98562.1 - 7.8e-13 48.5 0.0 1.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EGF98562.1 - 6.4e-12 45.7 7.3 1.1e-11 44.9 7.3 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EGF98562.1 - 0.0066 17.1 0.0 0.042 14.5 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain COX15-CtaA PF02628.15 EGF98565.1 - 1.3e-12 47.4 0.0 1.4e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein JmjC PF02373.22 EGF98566.1 - 2.2e-11 44.2 0.1 2.8e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EGF98566.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain NAD_binding_6 PF08030.12 EGF98567.1 - 1.1e-26 93.8 0.0 1.9e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGF98567.1 - 1.3e-18 67.0 0.0 2.9e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EGF98567.1 - 4.2e-09 36.6 13.2 5.3e-09 36.3 5.7 2.3 1 1 0 2 2 2 2 Ferric reductase like transmembrane component Ntox3 PF15536.6 EGF98567.1 - 0.004 17.2 0.0 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial toxin 3 NAD_binding_1 PF00175.21 EGF98567.1 - 0.044 14.4 0.0 0.23 12.1 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain ERG4_ERG24 PF01222.17 EGF98568.1 - 1.2e-113 380.1 20.1 1.4e-113 379.9 20.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGF98568.1 - 0.00029 20.4 0.7 0.00093 18.8 0.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) TAL_FSA PF00923.19 EGF98570.1 - 2.9e-94 315.6 0.0 3.3e-94 315.4 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Peptidase_M20 PF01546.28 EGF98572.1 - 1.1e-37 129.8 0.0 1.4e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGF98572.1 - 3.4e-14 52.7 0.0 6.2e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain p450 PF00067.22 EGF98573.1 - 1.1e-16 60.7 0.0 3.2e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Acetyltransf_1 PF00583.25 EGF98575.1 - 1.5e-12 47.8 0.0 1.9e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGF98575.1 - 1.9e-09 37.8 0.0 2.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGF98575.1 - 2e-09 37.4 0.0 2.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGF98575.1 - 7.1e-05 22.7 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EGF98575.1 - 0.00012 22.2 0.0 0.00014 22.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGF98575.1 - 0.0054 16.4 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EGF98575.1 - 0.0059 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 EGF98575.1 - 0.012 15.7 0.1 0.022 14.8 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGF98575.1 - 0.016 14.7 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase PanZ PF12568.8 EGF98575.1 - 0.031 14.0 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 EGF98575.1 - 0.11 13.1 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amino_oxidase PF01593.24 EGF98576.1 - 7e-31 108.0 0.0 1.6e-29 103.5 0.0 2.4 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGF98576.1 - 1.5e-13 50.8 0.0 3.5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGF98576.1 - 1.7e-09 37.8 0.1 2.1e-08 34.1 0.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGF98576.1 - 1e-06 28.2 0.0 6.2e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGF98576.1 - 0.00049 19.3 0.4 0.0036 16.4 1.2 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EGF98576.1 - 0.00066 20.2 0.2 0.12 12.9 0.3 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGF98576.1 - 0.00077 18.9 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase MCRA PF06100.11 EGF98576.1 - 0.0073 15.2 0.0 0.7 8.6 0.0 2.1 2 0 0 2 2 2 1 MCRA family Arena_nucleocap PF00843.17 EGF98576.1 - 0.059 12.3 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Arenavirus nucleocapsid N-terminal domain ApbA PF02558.16 EGF98576.1 - 0.066 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 EGF98576.1 - 0.069 12.4 0.4 0.12 11.6 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain GDI PF00996.18 EGF98576.1 - 0.077 11.5 0.0 0.21 10.1 0.0 1.6 2 0 0 2 2 2 0 GDP dissociation inhibitor NAD_binding_9 PF13454.6 EGF98576.1 - 0.12 12.4 0.1 0.74 9.8 0.1 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EGF98576.1 - 0.27 9.9 0.1 2.4 6.8 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein Glyco_transf_22 PF03901.17 EGF98578.1 - 1e-31 110.6 27.3 1.1e-30 107.2 27.3 2.0 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Thaumatin PF00314.17 EGF98579.1 - 4.9e-20 72.1 1.6 5.6e-20 71.9 1.6 1.0 1 0 0 1 1 1 1 Thaumatin family Methyltransf_12 PF08242.12 EGF98580.1 - 0.069 13.9 0.3 0.14 12.9 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase domain Glyco_transf_22 PF03901.17 EGF98582.1 - 9.3e-86 288.6 24.7 1.2e-85 288.3 24.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 EGF98582.1 - 0.061 13.5 10.5 0.14 12.4 10.5 1.7 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Totivirus_coat PF05518.11 EGF98583.1 - 1.2 7.1 6.7 1.6 6.7 6.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein DUF755 PF05501.11 EGF98588.1 - 0.0031 17.8 17.8 0.0031 17.8 17.8 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF755) Draxin PF15550.6 EGF98588.1 - 0.14 12.0 12.3 0.16 11.8 12.3 1.1 1 0 0 1 1 1 0 Draxin Cwf_Cwc_15 PF04889.12 EGF98588.1 - 0.25 11.0 18.2 0.41 10.4 18.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Coilin_N PF15862.5 EGF98588.1 - 0.35 10.7 10.3 0.036 13.9 1.6 2.4 1 1 1 2 2 2 0 Coilin N-terminus Peptidase_S49_N PF08496.10 EGF98588.1 - 1.1 9.3 7.1 2 8.5 7.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SURF2 PF05477.11 EGF98588.1 - 4.5 6.9 20.7 6.7 6.3 20.7 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Galactosyl_T PF01762.21 EGF98589.1 - 2.8e-09 37.1 0.0 0.0049 16.7 0.0 3.3 2 1 1 3 3 3 3 Galactosyltransferase PUF PF00806.19 EGF98590.1 - 1.7e-52 172.3 3.2 1.7e-06 27.4 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DAGK_cat PF00781.24 EGF98591.1 - 1.2e-24 86.3 0.2 1.9e-24 85.7 0.2 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Herpes_LMP1 PF05297.11 EGF98596.1 - 0.4 9.8 5.8 0.58 9.3 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3835 PF12927.7 EGF98596.1 - 7.5 7.5 7.0 3.5 8.6 3.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3835) DUF21 PF01595.20 EGF98601.1 - 1.1e-38 132.6 0.0 1.7e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EGF98601.1 - 0.0008 19.8 0.0 1.1 9.8 0.0 3.8 3 0 0 3 3 3 1 CBS domain Glyco_hydro81C PF17652.1 EGF98604.1 - 8.6e-112 373.8 0.1 1.2e-111 373.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EGF98604.1 - 2.6e-50 171.4 0.8 5e-50 170.5 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Clr5 PF14420.6 EGF98605.1 - 0.0044 17.2 0.0 0.98 9.7 0.1 2.5 3 0 0 3 3 3 2 Clr5 domain HTH_32 PF13565.6 EGF98605.1 - 0.011 16.3 1.1 0.48 11.1 0.0 2.8 1 1 1 2 2 2 0 Homeodomain-like domain MerR_1 PF13411.6 EGF98605.1 - 0.081 13.0 0.1 16 5.7 0.0 2.5 2 0 0 2 2 2 0 MerR HTH family regulatory protein YlmH_RBD PF17774.1 EGF98605.1 - 0.13 12.6 0.0 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative RNA-binding domain in YlmH PI3_PI4_kinase PF00454.27 EGF98606.1 - 1.3e-11 44.8 0.0 1.4e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Retrotran_gag_2 PF14223.6 EGF98607.1 - 5.3e-05 22.9 0.5 8.2e-05 22.3 0.5 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGF98607.1 - 0.026 14.3 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF2339 PF10101.9 EGF98608.1 - 0.027 13.1 0.1 0.035 12.7 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Erg28 PF03694.13 EGF98609.1 - 2.6e-40 137.2 1.7 3.1e-40 137.0 1.7 1.0 1 0 0 1 1 1 1 Erg28 like protein NAD_binding_8 PF13450.6 EGF98610.1 - 7.8e-10 38.9 0.3 1.7e-09 37.8 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGF98610.1 - 7.4e-09 35.4 0.0 1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EGF98610.1 - 0.00044 19.6 0.2 0.00068 19.0 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGF98610.1 - 0.00053 19.7 0.0 0.00077 19.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGF98610.1 - 0.0026 17.0 0.1 0.005 16.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGF98610.1 - 0.0033 16.7 0.1 0.005 16.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EGF98610.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 EGF98610.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EGF98610.1 - 0.021 13.9 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 EGF98610.1 - 0.039 14.2 0.0 0.088 13.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_oxidored PF12831.7 EGF98610.1 - 0.047 13.0 0.2 0.082 12.2 0.2 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EGF98610.1 - 0.095 11.4 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein KDZ PF18758.1 EGF98611.1 - 2.1e-24 86.4 0.1 2.1e-23 83.1 0.1 2.1 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF4298 PF14131.6 EGF98611.1 - 0.074 13.0 0.9 0.15 12.1 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) GAS PF13851.6 EGF98612.1 - 0.034 13.5 0.3 0.065 12.6 0.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding zf-C4H2 PF10146.9 EGF98612.1 - 1.3 9.3 7.1 0.14 12.4 1.2 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein STE3 PF02076.15 EGF98614.1 - 1.4e-78 264.1 7.7 1.8e-78 263.7 7.7 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF4010 PF13194.6 EGF98614.1 - 0.013 15.1 0.1 0.032 13.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) DUF4234 PF14018.6 EGF98614.1 - 0.24 11.6 1.8 0.6 10.3 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) RP-C_C PF11800.8 EGF98619.1 - 0.051 13.7 3.5 0.15 12.1 3.5 1.8 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4936 PF16290.5 EGF98619.1 - 0.064 13.9 0.0 0.2 12.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4936) BIRC6 PF12356.8 EGF98619.1 - 0.39 10.1 5.5 0.74 9.2 5.5 1.4 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 NPR3 PF03666.13 EGF98619.1 - 0.45 9.3 6.3 0.74 8.5 6.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nucleo_P87 PF07267.11 EGF98619.1 - 0.83 8.4 6.7 1.5 7.6 6.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 EGF98619.1 - 6.2 5.5 4.8 9.3 4.9 4.8 1.3 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 EGF98619.1 - 6.9 6.4 13.8 19 5.0 13.8 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4936 PF16290.5 EGF98628.1 - 0.069 13.8 0.0 0.21 12.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4936) NPR3 PF03666.13 EGF98628.1 - 0.32 9.7 6.0 0.6 8.8 6.0 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BIRC6 PF12356.8 EGF98628.1 - 0.39 10.1 5.5 0.69 9.3 5.5 1.4 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 CDT1_C PF16679.5 EGF98628.1 - 0.5 10.8 0.0 0.5 10.8 0.0 2.3 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain RP-C_C PF11800.8 EGF98628.1 - 0.77 9.8 7.9 0.14 12.2 3.5 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region FAR1 PF03101.15 EGF98629.1 - 0.086 13.5 0.1 0.27 11.9 0.1 1.9 1 0 0 1 1 1 0 FAR1 DNA-binding domain DUF1455 PF07306.11 EGF98631.1 - 0.15 12.1 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) DUF630 PF04783.12 EGF98631.1 - 0.49 10.6 4.6 7.1 6.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF630) Gp_dh_C PF02800.20 EGF98632.1 - 7.7e-45 152.3 0.0 1.7e-44 151.2 0.0 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EGF98632.1 - 5.3e-40 135.9 0.4 1.4e-38 131.3 0.1 2.3 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGF98632.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Retrotran_gag_2 PF14223.6 EGF98633.1 - 1.5e-07 31.2 4.2 2.2e-07 30.6 0.3 2.5 2 1 1 3 3 3 1 gag-polypeptide of LTR copia-type SIMPL PF04402.14 EGF98633.1 - 0.054 13.9 4.4 0.094 13.2 3.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF541) WIF PF02019.18 EGF98633.1 - 0.06 13.1 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 WIF domain GlutR_dimer PF00745.20 EGF98633.1 - 0.18 12.2 2.1 8.1 7.0 0.0 3.0 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Spore_GerAC PF05504.11 EGF98633.1 - 2.3 8.4 6.8 0.24 11.6 1.8 1.9 2 1 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal HALZ PF02183.18 EGF98634.1 - 0.08 13.2 0.3 0.22 11.8 0.3 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper KDZ PF18758.1 EGF98638.1 - 9.7e-26 90.7 0.0 1.4e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase zf-C4H2 PF10146.9 EGF98639.1 - 0.0013 19.1 5.9 0.0031 17.9 5.5 1.9 2 0 0 2 2 2 1 Zinc finger-containing protein Peptidase_S64 PF08192.11 EGF98639.1 - 0.036 12.6 5.3 0.055 12.0 5.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF2946 PF11162.8 EGF98640.1 - 0.033 14.9 0.0 0.033 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) CxC1 PF18802.1 EGF98641.1 - 1.2e-31 109.0 0.4 2.6e-31 107.8 0.4 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF98641.1 - 0.00015 21.9 0.2 0.00037 20.6 0.2 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGF98641.1 - 0.0062 16.2 0.3 0.15 11.7 0.0 2.5 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC3 PF18804.1 EGF98641.1 - 0.075 12.9 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Pkinase PF00069.25 EGF98645.1 - 5.2e-67 226.0 0.0 6.2e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF98645.1 - 1e-29 103.6 0.0 1.6e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF98645.1 - 0.00028 20.3 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF98645.1 - 0.0027 17.1 0.2 0.0057 16.0 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGF98645.1 - 0.0037 16.9 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EGF98645.1 - 0.0044 16.0 0.1 0.0068 15.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGF98645.1 - 0.037 14.0 0.3 0.14 12.1 0.4 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family gag-asp_proteas PF13975.6 EGF98646.1 - 0.093 13.3 0.0 0.29 11.7 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DMA PF03474.14 EGF98646.1 - 0.1 12.2 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 DMRTA motif DUF2203 PF09969.9 EGF98646.1 - 0.15 12.8 0.9 1.3 9.7 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Asp_protease_2 PF13650.6 EGF98646.1 - 0.16 12.6 0.0 0.62 10.7 0.0 2.1 1 0 0 1 1 1 0 Aspartyl protease DUF948 PF06103.11 EGF98646.1 - 1.5 9.1 8.3 0.17 12.2 1.6 2.7 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 EGF98646.1 - 4.3 7.8 9.4 0.54 10.7 0.4 2.9 2 1 0 2 2 2 0 Syntaxin-like protein NAD_binding_1 PF00175.21 EGF98647.1 - 8.7e-10 39.2 0.0 1.7e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGF98647.1 - 2.3e-06 27.9 0.0 4.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGF98647.1 - 8e-06 26.1 0.1 0.00094 19.3 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain THUMP PF02926.17 EGF98649.1 - 0.057 13.5 0.1 0.076 13.1 0.1 1.1 1 0 0 1 1 1 0 THUMP domain FHA PF00498.26 EGF98650.1 - 3.7e-13 49.6 1.1 8.2e-13 48.5 0.1 2.2 2 0 0 2 2 2 1 FHA domain zf-RING_11 PF17123.5 EGF98650.1 - 2e-10 40.2 11.5 3.5e-10 39.4 11.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGF98650.1 - 6.9e-07 29.5 12.8 1.1e-06 28.8 12.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGF98650.1 - 0.01 16.1 9.6 0.023 15.0 9.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGF98650.1 - 0.018 14.9 12.2 0.031 14.1 12.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF98650.1 - 0.019 14.8 13.8 0.034 14.0 13.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGF98650.1 - 0.027 14.5 5.7 0.049 13.7 5.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGF98650.1 - 0.22 11.2 8.0 0.36 10.5 8.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EGF98650.1 - 0.34 10.9 11.4 0.68 9.9 11.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 EGF98650.1 - 1.6 8.6 8.4 3.3 7.7 8.4 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 EGF98650.1 - 2.2 8.4 11.9 5.4 7.1 11.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Glycos_transf_2 PF00535.26 EGF98653.1 - 2.6e-22 79.4 0.0 7.1e-22 78.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGF98653.1 - 9.7e-06 25.6 0.0 2.2e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EGF98653.1 - 0.032 13.7 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ORC4_C PF14629.6 EGF98653.1 - 0.13 11.7 0.3 0.27 10.6 0.3 1.5 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Ribosomal_L28 PF00830.19 EGF98654.1 - 2e-17 63.1 1.1 6.3e-17 61.5 0.2 2.2 2 0 0 2 2 2 1 Ribosomal L28 family DIOX_N PF14226.6 EGF98655.1 - 1.4e-17 64.6 0.0 2.6e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGF98655.1 - 1.4e-16 60.8 0.1 2.5e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_1 PF01979.20 EGF98658.1 - 1.1e-25 90.7 0.0 1.5e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGF98658.1 - 4.8e-08 32.9 0.0 0.0081 15.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 EGF98658.1 - 0.05 13.4 0.0 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 Amidohydrolase Aldolase_II PF00596.21 EGF98659.1 - 9.2e-46 156.1 0.0 1.1e-45 155.9 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SOSSC PF15925.5 EGF98660.1 - 0.5 11.7 2.4 45 5.4 0.0 3.1 3 1 0 3 3 3 0 SOSS complex subunit C CoA_trans PF01144.23 EGF98661.1 - 3.3e-103 343.7 0.0 4.3e-60 202.8 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EGF98661.1 - 0.013 15.5 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Sel1 PF08238.12 EGF98662.1 - 2.8e-11 43.7 2.6 7.4e-08 32.8 0.4 3.3 3 0 0 3 3 3 3 Sel1 repeat HLH PF00010.26 EGF98663.1 - 1.8e-11 43.8 0.3 7.4e-11 41.8 0.1 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Snf7 PF03357.21 EGF98664.1 - 1.5e-29 102.8 27.2 1.5e-29 102.8 27.2 1.4 1 1 0 1 1 1 1 Snf7 Glyco_hydro_59M PF17387.2 EGF98664.1 - 0.2 11.8 1.7 2.1 8.5 0.1 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 59 central domain FAD_binding_3 PF01494.19 EGF98665.1 - 3.8e-93 312.5 0.0 4.2e-92 309.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGF98665.1 - 2.6e-49 167.4 0.0 5e-49 166.5 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 EGF98665.1 - 3.2e-05 23.2 0.6 5.2e-05 22.5 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGF98665.1 - 3.2e-05 24.1 0.1 9.6e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGF98665.1 - 7.2e-05 22.1 0.1 0.002 17.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EGF98665.1 - 7.2e-05 21.7 0.2 0.00012 20.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGF98665.1 - 0.00045 19.6 0.2 0.00071 18.9 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGF98665.1 - 0.00051 19.4 0.1 0.0011 18.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGF98665.1 - 0.00081 18.4 0.2 0.0014 17.6 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 EGF98665.1 - 0.00095 18.8 0.1 0.0018 17.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.21 EGF98665.1 - 0.0017 17.8 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family Lycopene_cycl PF05834.12 EGF98665.1 - 0.0063 15.6 0.2 0.016 14.3 0.2 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 EGF98665.1 - 0.0096 15.0 0.3 0.015 14.4 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EGF98665.1 - 0.012 14.9 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EGF98665.1 - 0.016 14.5 0.7 0.025 13.9 0.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 EGF98665.1 - 0.02 14.5 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 EGF98665.1 - 0.044 14.3 0.1 0.087 13.4 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TruD PF01142.18 EGF98665.1 - 0.051 12.4 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) Glu_dehyd_C PF16912.5 EGF98665.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ApbA PF02558.16 EGF98665.1 - 0.18 11.5 0.1 0.33 10.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EGF98665.1 - 0.2 11.7 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ARD PF03079.14 EGF98668.1 - 5.1e-46 156.7 1.0 6.1e-46 156.5 1.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EGF98668.1 - 2.8e-09 36.6 0.0 6.4e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGF98668.1 - 1.3e-07 31.6 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EGF98668.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EGF98668.1 - 0.034 13.8 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Lyx_isomer PF07385.12 EGF98668.1 - 0.036 13.3 0.0 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 D-lyxose isomerase RHH_1 PF01402.21 EGF98668.1 - 0.074 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family S8_pro-domain PF16470.5 EGF98668.1 - 0.083 13.7 0.2 0.55 11.0 0.1 2.2 1 1 0 1 1 1 0 Peptidase S8 pro-domain MAP17 PF15807.5 EGF98669.1 - 0.31 11.3 3.4 0.35 11.1 3.4 1.0 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LisH PF08513.11 EGF98670.1 - 3.5e-06 26.8 0.0 6.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 LisH WD40 PF00400.32 EGF98671.1 - 6.3e-36 121.8 21.8 4.6e-07 30.4 0.3 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF98671.1 - 6.8e-15 55.1 1.6 0.009 16.3 0.0 6.4 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EGF98671.1 - 5e-09 35.9 0.1 2.1e-08 33.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like WD40_like PF17005.5 EGF98671.1 - 1.3e-06 28.0 0.0 0.051 12.9 0.0 4.3 2 1 2 5 5 5 3 WD40-like domain Nup160 PF11715.8 EGF98671.1 - 0.00011 21.1 0.8 5.3 5.6 0.0 4.2 2 1 1 4 4 4 2 Nucleoporin Nup120/160 F-box PF00646.33 EGF98671.1 - 0.0013 18.6 2.1 0.0013 18.6 0.2 2.1 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.6 EGF98671.1 - 0.0037 16.9 0.2 0.19 11.3 0.2 2.7 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 EGF98671.1 - 0.0046 17.4 4.8 10 6.8 0.0 5.1 4 1 1 5 5 5 1 PQQ-like domain DUF5046 PF16465.5 EGF98671.1 - 0.16 11.4 0.0 18 4.7 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) PHD PF00628.29 EGF98673.1 - 1.2e-07 31.5 0.6 2.5e-07 30.5 0.6 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 EGF98673.1 - 0.048 13.5 0.4 0.08 12.8 0.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EGF98673.1 - 0.22 11.9 1.6 0.57 10.5 1.6 1.7 1 0 0 1 1 1 0 C1 domain Cofilin_ADF PF00241.20 EGF98674.1 - 4.1e-23 81.5 0.0 8.6e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_9 PF14604.6 EGF98674.1 - 5.3e-23 80.6 2.1 1.2e-11 44.3 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EGF98674.1 - 1.2e-22 79.2 3.1 2.3e-11 43.1 0.2 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGF98674.1 - 4.7e-14 51.8 0.1 2.3e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Lactamase_B_2 PF12706.7 EGF98675.1 - 1.1e-32 113.3 0.0 1.6e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGF98675.1 - 2.7e-11 43.6 0.0 4.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGF98675.1 - 0.0021 18.1 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RRM_1 PF00076.22 EGF98676.1 - 6.5e-15 54.7 0.0 1.5e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TEA PF01285.18 EGF98677.1 - 3.6e-21 75.0 0.1 4.1e-20 71.6 0.0 2.4 1 1 1 2 2 2 2 TEA/ATTS domain SAM_2 PF07647.17 EGF98678.1 - 4.5e-10 39.5 0.0 1.5e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGF98678.1 - 5.3e-07 30.0 0.0 1.3e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 EGF98678.1 - 0.00038 20.2 0.0 0.041 13.7 0.0 3.1 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 EGF98678.1 - 0.00075 19.1 0.0 0.23 11.1 0.0 2.8 3 0 0 3 3 3 2 SH3 domain SAM_PNT PF02198.16 EGF98678.1 - 0.0041 17.1 0.0 0.015 15.3 0.0 2.0 1 1 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 EGF98678.1 - 0.047 13.5 1.2 0.1 12.4 0.1 2.2 2 1 0 2 2 2 0 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 EGF98678.1 - 0.15 11.7 0.1 1.7 8.3 0.0 2.5 3 0 0 3 3 3 0 Variant SH3 domain MFAP1 PF06991.11 EGF98678.1 - 0.23 11.3 0.1 0.4 10.5 0.1 1.3 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Alpha_kinase PF02816.18 EGF98679.1 - 2.3e-20 73.5 0.0 4.3e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Alpha-kinase family NAD_binding_8 PF13450.6 EGF98680.1 - 5.8e-06 26.5 0.0 3.2e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain XPA_C PF05181.12 EGF98685.1 - 3.3e-24 84.6 2.4 3.3e-24 84.6 2.4 2.4 3 0 0 3 3 3 1 XPA protein C-terminus XPA_N PF01286.18 EGF98685.1 - 5.9e-06 26.2 0.6 5.9e-06 26.2 0.6 2.4 3 0 0 3 3 3 1 XPA protein N-terminal Zn-ribbon_8 PF09723.10 EGF98685.1 - 1.2 9.4 6.9 7.3 6.8 0.1 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_3 PF13878.6 EGF98685.1 - 1.8 8.5 8.1 30 4.5 0.3 3.7 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO YojJ PF10372.9 EGF98687.1 - 0.042 13.9 0.1 0.065 13.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Mastoparan_2 PF08251.11 EGF98687.1 - 0.25 11.6 2.1 0.7 10.3 0.2 2.5 2 0 0 2 2 2 0 Mastoparan peptide FAD_binding_8 PF08022.12 EGF98688.1 - 1.1e-19 70.5 0.0 2e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EGF98688.1 - 8.5e-08 32.4 2.2 1.4e-07 31.7 2.2 1.3 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGF98688.1 - 0.00017 21.8 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ntox3 PF15536.6 EGF98688.1 - 0.026 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 3 2TM PF13239.6 EGF98688.1 - 0.041 14.2 0.4 0.099 13.0 0.4 1.6 1 0 0 1 1 1 0 2TM domain FAD_binding_6 PF00970.24 EGF98688.1 - 0.071 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain MTS PF05175.14 EGF98691.1 - 6.8e-06 25.7 0.2 0.052 13.1 0.1 2.2 1 1 1 2 2 2 2 Methyltransferase small domain PrmA PF06325.13 EGF98691.1 - 0.0097 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EGF98691.1 - 0.01 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase DHHW PF14286.6 EGF98691.1 - 0.15 11.4 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 DHHW protein SLM4 PF16818.5 EGF98692.1 - 0.98 9.4 8.3 1.3 8.9 8.1 1.4 1 1 0 1 1 1 0 Protein SLM4 Ku_PK_bind PF08785.11 EGF98692.1 - 3.4 7.8 10.1 23 5.2 0.9 3.1 2 1 1 3 3 3 0 Ku C terminal domain like RRM_1 PF00076.22 EGF98694.1 - 3.5e-29 100.4 0.0 2.7e-15 56.0 0.1 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EGF98694.1 - 0.0053 16.9 0.8 0.039 14.1 0.2 2.6 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.8 EGF98694.1 - 0.039 14.0 0.2 10 6.3 0.0 3.3 3 0 0 3 3 3 0 Limkain b1 RRM_7 PF16367.5 EGF98694.1 - 0.079 13.1 0.0 0.95 9.6 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif Het-C PF07217.11 EGF98696.1 - 1.2e-200 667.8 0.0 1.7e-200 667.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C CxC5 PF18718.1 EGF98698.1 - 3e-28 98.3 9.7 4.9e-28 97.6 9.7 1.4 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGF98698.1 - 1.4e-20 73.3 0.5 1.4e-20 73.3 0.5 2.1 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases F-box-like_2 PF13013.6 EGF98699.1 - 0.15 12.0 0.3 7.3 6.6 0.0 2.4 2 0 0 2 2 2 0 F-box-like domain LRR_4 PF12799.7 EGF98699.1 - 3.2 8.3 9.3 29 5.3 0.2 4.8 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) STE PF02200.16 EGF98701.1 - 4.2e-53 178.4 0.0 8.4e-53 177.5 0.0 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EGF98701.1 - 1.1e-11 44.5 9.4 8.4e-06 26.0 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGF98701.1 - 1.9e-07 31.2 5.2 1.9e-07 31.2 5.2 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF98701.1 - 1e-06 29.0 7.7 0.0022 18.7 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGF98701.1 - 0.0072 16.6 0.9 0.063 13.6 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 EGF98701.1 - 0.059 13.8 5.6 0.25 11.8 0.8 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 EGF98701.1 - 0.2 11.5 8.9 0.59 9.9 0.5 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 EGF98701.1 - 1.2 9.2 4.5 0.36 10.9 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Plasmodium_Vir PF05795.11 EGF98702.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1640 PF07798.11 EGF98704.1 - 3.5e-39 134.6 1.3 5.7e-39 134.0 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GCN5L1 PF06320.13 EGF98704.1 - 0.055 13.6 1.3 0.13 12.4 1.3 1.6 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) ORF6C PF10552.9 EGF98704.1 - 0.25 11.4 2.5 10 6.2 0.0 2.9 2 1 1 3 3 3 0 ORF6C domain Vps53_N PF04100.12 EGF98704.1 - 0.45 9.4 4.7 3.2 6.6 2.8 2.1 1 1 1 2 2 2 0 Vps53-like, N-terminal HIP1_clath_bdg PF16515.5 EGF98704.1 - 0.46 11.1 6.0 0.23 12.1 1.8 2.4 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3864 PF12980.7 EGF98704.1 - 0.54 10.6 2.5 0.36 11.2 0.2 1.9 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3864) Acyl-CoA_dh_1 PF00441.24 EGF98705.1 - 3.1e-31 108.6 0.4 4.6e-31 108.1 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGF98705.1 - 2.2e-19 69.4 0.0 4.1e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGF98705.1 - 7.6e-13 49.1 0.0 1.8e-12 47.9 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGF98705.1 - 1.1e-08 35.4 0.3 1.8e-08 34.7 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EGF98705.1 - 0.013 15.2 0.1 0.04 13.6 0.0 1.8 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal CDC37_N PF03234.14 EGF98706.1 - 1.4e-39 135.9 5.9 1.4e-39 135.9 5.9 3.0 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EGF98706.1 - 1.4e-32 112.1 0.3 1.6e-31 108.7 0.0 2.5 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EGF98706.1 - 1.1e-19 70.4 5.0 1.1e-19 70.4 5.0 3.3 3 0 0 3 3 3 1 Cdc37 C terminal domain PP2C_C PF07830.13 EGF98706.1 - 1.5 9.4 6.4 0.42 11.1 0.8 3.0 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Mad3_BUB1_I PF08311.12 EGF98708.1 - 0.11 12.5 2.3 3 7.9 0.3 2.6 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 DUF5517 PF17639.2 EGF98708.1 - 0.27 11.5 2.7 0.76 10.1 2.7 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5517) Sedlin_N PF04628.13 EGF98709.1 - 2.4e-22 79.5 0.0 2.9e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EGF98709.1 - 0.0068 16.3 0.2 0.023 14.6 0.2 1.9 1 1 0 1 1 1 1 Sybindin-like family DDE_3 PF13358.6 EGF98710.1 - 1.9e-06 27.7 0.0 4.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3349 PF11829.8 EGF98710.1 - 0.085 13.6 0.2 0.18 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) NAM-associated PF14303.6 EGF98713.1 - 7.9e-07 29.9 1.4 9e-07 29.8 1.4 1.0 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain eIF3_N PF09440.10 EGF98713.1 - 0.034 14.6 1.1 0.053 14.0 1.1 1.3 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain DUF2387 PF09526.10 EGF98714.1 - 0.13 12.4 0.5 0.31 11.2 0.5 1.6 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) TTSSLRR PF12468.8 EGF98717.1 - 0.18 12.1 2.9 0.25 11.6 0.2 2.6 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Ribosomal_L27 PF01016.19 EGF98718.1 - 1.2e-31 108.6 1.4 2e-31 107.9 1.4 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein NifU_N PF01592.16 EGF98719.1 - 9.7e-54 180.9 0.4 4e-53 178.9 0.1 1.8 1 1 1 2 2 2 1 NifU-like N terminal domain MIR PF02815.19 EGF98720.1 - 0.065 13.1 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 MIR domain Pex14_N PF04695.13 EGF98721.1 - 1.2e-20 74.8 0.4 1.9e-15 57.9 0.2 4.0 2 2 1 3 3 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.9 EGF98721.1 - 0.0029 18.0 6.7 0.0043 17.4 6.7 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein DUF4407 PF14362.6 EGF98721.1 - 0.0047 16.3 2.5 0.0066 15.8 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) FapA PF03961.13 EGF98721.1 - 0.0081 14.8 6.8 0.011 14.4 6.8 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A V_ATPase_I PF01496.19 EGF98721.1 - 0.0093 13.9 1.3 0.011 13.7 1.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 EGF98721.1 - 0.012 15.7 7.3 0.059 13.4 7.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 EGF98721.1 - 0.012 14.5 2.0 0.018 14.0 2.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_13 PF13166.6 EGF98721.1 - 0.02 13.6 9.5 0.031 12.9 9.5 1.2 1 0 0 1 1 1 0 AAA domain CLZ PF16526.5 EGF98721.1 - 0.03 14.7 11.1 0.4 11.1 1.4 3.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 EGF98721.1 - 0.054 12.4 13.3 0.087 11.7 13.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0240 PF06784.11 EGF98721.1 - 0.057 13.5 2.8 0.11 12.5 2.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) Exonuc_VII_L PF02601.15 EGF98721.1 - 0.059 12.9 1.7 0.079 12.5 1.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 EGF98721.1 - 0.09 10.3 10.2 0.13 9.8 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prominin PF05478.11 EGF98721.1 - 0.11 10.4 5.3 0.15 10.0 5.3 1.1 1 0 0 1 1 1 0 Prominin LPP PF04728.13 EGF98721.1 - 0.16 12.4 3.9 0.52 10.7 0.4 2.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Golgin_A5 PF09787.9 EGF98721.1 - 0.16 11.4 12.3 0.27 10.7 12.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Histidinol_dh PF00815.20 EGF98721.1 - 0.18 10.8 3.4 0.26 10.2 3.4 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase Phage_connect_1 PF05135.13 EGF98721.1 - 0.2 12.2 3.9 0.24 11.9 2.4 1.9 1 1 0 2 2 1 0 Phage gp6-like head-tail connector protein BCAS2 PF05700.11 EGF98721.1 - 0.24 11.0 7.6 0.47 10.1 7.6 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) TMPIT PF07851.13 EGF98721.1 - 0.26 10.5 10.2 0.4 9.9 10.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein CHASE3 PF05227.13 EGF98721.1 - 0.3 11.0 5.4 0.68 9.8 2.2 2.6 2 1 1 3 3 3 0 CHASE3 domain HbrB PF08539.11 EGF98721.1 - 0.32 11.0 4.2 0.34 10.9 3.0 1.7 1 1 1 2 2 2 0 HbrB-like DUF4164 PF13747.6 EGF98721.1 - 0.42 10.9 9.6 9.4 6.6 4.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Atg14 PF10186.9 EGF98721.1 - 0.46 9.5 8.1 0.73 8.9 8.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 EGF98721.1 - 0.53 10.6 7.6 2.8 8.3 4.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PCRF PF03462.18 EGF98721.1 - 0.7 9.7 10.9 1.2 8.9 10.9 1.3 1 0 0 1 1 1 0 PCRF domain DUF3552 PF12072.8 EGF98721.1 - 1.2 8.5 14.8 2.2 7.6 14.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1043 PF06295.12 EGF98721.1 - 1.2 9.1 14.7 0.14 12.1 7.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Baculo_PEP_C PF04513.12 EGF98721.1 - 1.5 8.8 8.7 1.3 9.1 4.4 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HIP1_clath_bdg PF16515.5 EGF98721.1 - 1.6 9.4 17.6 0.54 10.9 10.8 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fib_alpha PF08702.10 EGF98721.1 - 2.9 8.1 14.7 5.8 7.1 14.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 EGF98721.1 - 3.2 8.1 9.7 3.2 8.1 7.6 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Tup_N PF08581.10 EGF98721.1 - 4.2 7.7 13.4 3.4 8.0 9.8 2.5 2 1 0 2 2 2 0 Tup N-terminal DUF16 PF01519.16 EGF98721.1 - 5.5 7.5 15.2 12 6.4 12.0 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Syntaxin-6_N PF09177.11 EGF98721.1 - 8.1 7.1 13.1 1.2e+02 3.3 7.9 3.2 1 1 0 2 2 2 0 Syntaxin 6, N-terminal MFS_1 PF07690.16 EGF98722.1 - 1e-34 120.0 51.6 4.1e-33 114.8 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha_kinase PF02816.18 EGF98725.1 - 0.0064 16.6 0.1 0.0094 16.1 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family AhpC-TSA PF00578.21 EGF98726.1 - 9.1e-31 106.4 0.0 1.2e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 EGF98726.1 - 2.5e-12 46.4 0.0 4.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 EGF98726.1 - 1.6e-09 37.7 0.0 2.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin Nop PF01798.18 EGF98727.1 - 2.8e-69 233.1 0.1 3.9e-69 232.6 0.1 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EGF98727.1 - 1.9e-41 141.7 4.1 4e-41 140.7 4.1 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain zf-LYAR PF08790.11 EGF98728.1 - 9.1e-13 47.9 4.1 9.1e-13 47.9 4.1 2.0 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 EGF98728.1 - 0.00064 19.3 0.5 0.15 11.6 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 EGF98728.1 - 0.001 19.4 3.9 0.0061 17.0 0.5 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EGF98728.1 - 0.0031 17.8 1.0 0.016 15.5 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGF98728.1 - 0.029 14.8 0.5 0.12 12.8 0.5 2.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGF98728.1 - 0.14 13.1 3.8 0.78 10.7 0.5 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-ACC PF17848.1 EGF98728.1 - 0.32 11.1 2.0 0.95 9.6 2.0 1.9 1 1 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf_C2H2_ZHX PF18387.1 EGF98728.1 - 1.4 8.7 4.9 3.3 7.4 0.9 2.9 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain MHYT PF03707.16 EGF98729.1 - 1.3e-06 28.5 6.5 0.00079 19.5 0.4 2.4 2 1 0 2 2 2 2 Bacterial signalling protein N terminal repeat MHYT PF03707.16 EGF98730.1 - 1.5e-05 25.0 11.9 0.00097 19.3 1.1 3.3 4 0 0 4 4 4 2 Bacterial signalling protein N terminal repeat Peptidase_U4 PF03419.13 EGF98730.1 - 0.83 8.9 6.9 1.5 8.1 6.9 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF4231 PF14015.6 EGF98730.1 - 0.93 10.0 4.2 0.78 10.2 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) CxC5 PF18718.1 EGF98731.1 - 4e-22 78.5 8.6 7.4e-22 77.6 8.6 1.4 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Med8 PF10232.9 EGF98733.1 - 1.4e-05 24.8 0.7 0.0019 17.8 0.1 2.2 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription complex subunit 8 Semialdhyde_dhC PF02774.18 EGF98735.1 - 3.6e-29 102.1 0.0 1.3e-28 100.3 0.0 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EGF98735.1 - 2.2e-28 99.1 0.0 3.9e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 EGF98735.1 - 0.00046 19.8 0.1 0.036 13.6 0.0 2.6 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.16 EGF98735.1 - 0.0041 17.8 0.0 0.015 16.1 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 EGF98735.1 - 0.0054 16.8 0.0 0.014 15.5 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2H-phosphodiest PF08975.10 EGF98736.1 - 0.12 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) Ras PF00071.22 EGF98737.1 - 3.9e-64 215.1 1.3 4.7e-64 214.9 1.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF98737.1 - 2.2e-35 121.4 0.3 4.4e-35 120.5 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF98737.1 - 1.6e-16 60.3 0.3 2e-16 59.9 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGF98737.1 - 2.1e-05 24.0 0.1 2.7e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGF98737.1 - 2.2e-05 24.0 0.1 2.6e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGF98737.1 - 3.5e-05 23.4 0.5 0.00011 21.9 0.3 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGF98737.1 - 4.9e-05 23.4 0.1 7.5e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF98737.1 - 5.1e-05 23.2 1.1 0.13 12.2 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 EGF98737.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF98737.1 - 0.016 15.6 0.0 0.025 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EGF98737.1 - 0.032 14.7 0.1 1.8 9.0 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGF98737.1 - 0.034 14.4 0.0 0.061 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGF98737.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EGF98737.1 - 0.068 12.7 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 EGF98737.1 - 0.08 12.5 0.1 0.95 9.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EGF98737.1 - 0.081 12.3 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein WD40 PF00400.32 EGF98738.1 - 8.5e-23 80.2 10.6 1.9e-06 28.5 0.3 7.3 6 2 1 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.14 EGF98738.1 - 2.2e-20 72.7 9.8 5e-20 71.6 9.8 1.6 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.11 EGF98738.1 - 6.5e-07 29.4 0.0 2.6e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Ins_P5_2-kin PF06090.12 EGF98740.1 - 0.057 12.8 0.4 0.061 12.8 0.4 1.2 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase CFEM PF05730.11 EGF98743.1 - 6.5e-14 51.8 7.9 8.5e-14 51.4 7.9 1.1 1 0 0 1 1 1 1 CFEM domain VSG_B PF13206.6 EGF98743.1 - 0.27 10.5 3.8 0.3 10.3 3.8 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Retrotran_gag_2 PF14223.6 EGF98745.1 - 1.8e-06 27.7 0.0 2.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type VWA PF00092.28 EGF98746.1 - 3.4e-06 27.4 0.0 4.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGF98746.1 - 0.0014 19.3 0.0 0.0023 18.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 EGF98746.1 - 0.0043 17.2 0.1 0.0056 16.8 0.1 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.14 EGF98746.1 - 0.1 11.9 0.4 0.24 10.8 0.4 1.7 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein Pex14_N PF04695.13 EGF98746.1 - 1 10.0 5.3 0.57 10.8 3.0 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 2OG-FeII_Oxy_2 PF13532.6 EGF98748.1 - 8.9e-28 97.8 0.0 1.1e-27 97.6 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGF98748.1 - 0.0041 17.6 0.0 0.0054 17.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily VWA PF00092.28 EGF98749.1 - 1.7e-05 25.1 0.0 2.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGF98749.1 - 0.00072 20.2 0.0 0.0027 18.3 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF4504 PF14953.6 EGF98750.1 - 1.7e-10 40.7 0.0 1.7e-06 27.7 0.0 2.1 1 1 0 2 2 2 2 Domain of unknown function (DUF4504) zf-C2H2_2 PF12756.7 EGF98751.1 - 0.15 12.5 0.1 0.15 12.5 0.1 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2303 PF10065.9 EGF98753.1 - 0.33 10.1 6.5 0.038 13.1 2.3 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2303) Zip PF02535.22 EGF98753.1 - 9.1 5.4 6.9 10 5.2 6.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Tyrosinase PF00264.20 EGF98756.1 - 3.1e-50 171.5 0.1 3.8e-50 171.2 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Pyr_excise PF03013.14 EGF98756.1 - 0.17 11.8 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Sec2p PF06428.11 EGF98757.1 - 4.3e-09 36.2 7.8 4.3e-09 36.2 7.8 3.1 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p PV-1 PF06637.11 EGF98757.1 - 0.0043 15.9 4.4 0.0076 15.1 4.4 1.3 1 0 0 1 1 1 1 PV-1 protein (PLVAP) NDUFV3 PF15880.5 EGF98757.1 - 0.024 14.7 0.2 0.54 10.3 0.0 2.4 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial Cortex-I_coil PF09304.10 EGF98757.1 - 0.092 13.0 13.1 0.25 11.6 8.7 2.9 2 0 0 2 2 2 0 Cortexillin I, coiled coil Occludin_ELL PF07303.13 EGF98757.1 - 0.14 12.9 6.5 0.21 12.3 4.5 2.3 2 0 0 2 2 2 0 Occludin homology domain Leu_zip PF15294.6 EGF98757.1 - 0.15 11.5 14.7 0.015 14.8 9.3 2.0 2 0 0 2 2 2 0 Leucine zipper NYD-SP28_assoc PF14775.6 EGF98757.1 - 0.27 11.4 2.3 0.65 10.1 2.3 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain GAS PF13851.6 EGF98757.1 - 0.77 9.1 19.2 0.033 13.5 13.2 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Med9 PF07544.13 EGF98757.1 - 1.4 9.1 8.3 1.1 9.4 4.6 2.7 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 bZIP_1 PF00170.21 EGF98757.1 - 4 7.6 11.1 0.71 10.0 4.7 2.7 1 1 1 2 2 2 0 bZIP transcription factor ZapB PF06005.12 EGF98757.1 - 7.1 7.2 17.5 0.59 10.6 8.2 3.2 2 1 1 3 3 3 0 Cell division protein ZapB DUF745 PF05335.13 EGF98757.1 - 9.5 5.9 9.7 4.6 6.9 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DNA_PPF PF02916.15 EGF98758.1 - 0.086 13.2 1.6 0.71 10.3 0.5 2.5 1 1 0 2 2 2 0 DNA polymerase processivity factor PmbA_TldD PF01523.16 EGF98759.1 - 0.0099 15.8 0.1 0.023 14.5 0.0 1.6 2 0 0 2 2 2 1 Putative modulator of DNA gyrase IU_nuc_hydro PF01156.19 EGF98759.1 - 0.095 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase HSBP1 PF06825.12 EGF98760.1 - 2.6e-14 52.8 0.1 3.7e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 SPX PF03105.19 EGF98760.1 - 0.00034 20.7 0.2 0.00038 20.5 0.2 1.1 1 0 0 1 1 1 1 SPX domain Macoilin PF09726.9 EGF98760.1 - 0.32 9.5 1.0 0.38 9.2 1.0 1.0 1 0 0 1 1 1 0 Macoilin family Parathyroid PF01279.17 EGF98763.1 - 0.0014 19.2 3.9 0.38 11.4 0.1 3.5 1 1 2 3 3 3 2 Parathyroid hormone family Kinesin_assoc PF16183.5 EGF98763.1 - 4.3 7.4 6.8 8.8 6.4 0.5 2.6 2 0 0 2 2 2 0 Kinesin-associated DUF2934 PF11154.8 EGF98763.1 - 5 6.9 7.2 7.2 6.4 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) SWIB PF02201.18 EGF98764.1 - 2.4e-15 56.2 0.5 2.4e-15 56.2 0.5 2.5 3 0 0 3 3 3 1 SWIB/MDM2 domain Glyco_hydro_10 PF00331.20 EGF98764.1 - 0.1 11.7 1.1 0.16 11.1 0.2 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 Aminotran_3 PF00202.21 EGF98767.1 - 4.3e-35 121.1 0.0 9.8e-18 64.0 0.0 3.2 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 EGF98767.1 - 4.6e-16 59.2 0.0 2.1e-15 57.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain GEP5 PF17053.5 EGF98767.1 - 0.15 11.9 0.0 4.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Genetic interactor of prohibitin 5 FR47 PF08445.10 EGF98767.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Opi1 PF08618.10 EGF98769.1 - 1.5e-174 581.2 1.9 1.5e-174 581.2 1.9 3.0 3 1 0 3 3 3 1 Transcription factor Opi1 7TM_GPCR_Sri PF10327.9 EGF98769.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Proteasome PF00227.26 EGF98770.1 - 4.3e-32 111.1 0.0 9.5e-32 110.0 0.1 1.5 2 0 0 2 2 2 1 Proteasome subunit MOZ_SAS PF01853.18 EGF98771.1 - 0.11 12.2 0.1 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 MOZ/SAS family SPACA7 PF15307.6 EGF98771.1 - 1.4 9.2 4.5 14 6.0 0.0 2.7 2 1 0 2 2 2 0 Sperm acrosome-associated protein 7 Ribonuclease_3 PF00636.26 EGF98772.1 - 7.6e-35 119.7 0.3 2.3e-16 60.3 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGF98772.1 - 9.7e-22 77.5 0.1 1.6e-07 31.5 0.1 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 EGF98772.1 - 1.1e-21 76.8 0.1 3.6e-20 71.9 0.1 2.8 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.29 EGF98772.1 - 6.8e-18 65.0 0.0 1.3e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGF98772.1 - 1.1e-12 48.3 0.0 2.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGF98772.1 - 1.5e-10 41.4 0.0 4.1e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2075 PF09848.9 EGF98772.1 - 0.0017 17.7 0.0 0.0051 16.1 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) dsrm PF00035.26 EGF98772.1 - 0.0019 18.8 0.0 2.4 9.0 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif AAA_22 PF13401.6 EGF98772.1 - 0.002 18.4 0.0 0.0064 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain FKBP_C PF00254.28 EGF98774.1 - 5e-32 110.1 0.0 5.8e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF1340 PF07067.11 EGF98775.1 - 0.059 12.8 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Cofilin_ADF PF00241.20 EGF98777.1 - 2.7e-41 140.2 0.1 3e-41 140.0 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PP2C PF00481.21 EGF98778.1 - 2.9e-76 256.5 0.0 4.2e-76 256.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C DUF4806 PF16064.5 EGF98778.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) SPX PF03105.19 EGF98778.1 - 0.31 10.9 4.1 0.46 10.3 4.1 1.3 1 0 0 1 1 1 0 SPX domain ABC_trans_N PF14510.6 EGF98779.1 - 0.038 14.6 0.3 0.038 14.6 0.3 2.1 1 1 1 2 2 2 0 ABC-transporter N-terminal DUF443 PF04276.12 EGF98780.1 - 0.095 12.5 0.7 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF443) DOR PF14839.6 EGF98781.1 - 0.13 12.2 2.3 0.2 11.6 2.3 1.2 1 0 0 1 1 1 0 DOR family MFS_1 PF07690.16 EGF98783.1 - 1.3e-14 53.9 38.1 1.2e-06 27.8 7.0 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily IncF PF17626.2 EGF98783.1 - 1.5 9.2 14.4 11 6.5 0.6 4.3 2 1 1 3 3 3 0 Inclusion membrane protein F Hpt PF01627.23 EGF98784.1 - 6.3e-10 39.2 0.4 9.5e-10 38.6 0.1 1.5 2 0 0 2 2 2 1 Hpt domain CH PF00307.31 EGF98785.1 - 5.8e-46 155.2 0.0 1.6e-23 83.0 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EGF98785.1 - 4.2e-20 71.6 0.0 1.6e-19 69.7 0.0 2.1 1 1 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EGF98785.1 - 1.2e-10 41.0 0.1 6.8e-06 25.8 0.1 2.6 2 0 0 2 2 2 2 CAMSAP CH domain Spectrin PF00435.21 EGF98785.1 - 0.0055 17.2 3.5 1.7 9.2 0.6 2.8 1 1 0 2 2 2 2 Spectrin repeat EF-hand_8 PF13833.6 EGF98785.1 - 0.0066 16.3 0.1 0.19 11.6 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair Baculo_PEP_C PF04513.12 EGF98785.1 - 0.025 14.6 1.3 0.81 9.7 0.4 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_14 PF17959.1 EGF98785.1 - 0.048 14.0 0.1 3.8 7.9 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain Prominin PF05478.11 EGF98785.1 - 0.055 11.4 2.0 2.5 5.9 0.1 2.1 1 1 1 2 2 2 0 Prominin BAR_3 PF16746.5 EGF98785.1 - 0.072 12.8 0.4 0.26 11.0 0.1 2.0 2 0 0 2 2 2 0 BAR domain of APPL family Apolipoprotein PF01442.18 EGF98785.1 - 0.89 9.4 6.4 5.5 6.8 0.8 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Eaf7 PF07904.13 EGF98787.1 - 4.4e-13 49.5 0.3 2.8e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Retrotrans_gag PF03732.17 EGF98791.1 - 0.18 12.1 0.0 0.43 10.9 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 EGF98792.1 - 6.2e-05 22.7 0.0 9.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type GRP PF07172.11 EGF98794.1 - 0.039 14.7 4.5 0.12 13.1 4.5 1.8 1 0 0 1 1 1 0 Glycine rich protein family CEP63 PF17045.5 EGF98796.1 - 0.019 14.8 4.1 0.032 14.1 4.1 1.3 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Lectin_N PF03954.14 EGF98796.1 - 0.06 13.1 0.3 0.18 11.6 0.3 1.7 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF2433 PF10360.9 EGF98796.1 - 0.11 12.6 0.7 0.25 11.4 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) TMPIT PF07851.13 EGF98796.1 - 0.51 9.5 3.0 0.85 8.8 3.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.10 EGF98796.1 - 2.4 8.3 7.9 0.31 11.2 1.8 2.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family ERM PF00769.19 EGF98796.1 - 3.7 7.3 11.3 0.32 10.8 5.3 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family SlyX PF04102.12 EGF98797.1 - 0.0015 19.1 0.5 0.019 15.6 0.0 3.1 3 0 0 3 3 3 1 SlyX DUF948 PF06103.11 EGF98797.1 - 0.075 13.3 0.6 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 EGF98797.1 - 1 9.6 4.1 4.3 7.5 1.9 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Motile_Sperm PF00635.26 EGF98798.1 - 9e-25 86.6 0.0 1.6e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 EGF98798.1 - 3.6e-06 27.1 0.1 7.3e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CENP-F_N PF10481.9 EGF98798.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Cenp-F N-terminal domain DUF4941 PF16299.5 EGF98799.1 - 0.07 12.4 0.0 0.083 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4941) DUF2353 PF09789.9 EGF98800.1 - 0.0024 17.3 1.2 0.0043 16.5 1.2 1.4 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) CENP-F_leu_zip PF10473.9 EGF98800.1 - 0.049 13.6 1.4 0.12 12.4 1.4 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 EGF98800.1 - 0.11 13.0 0.9 0.23 12.0 0.9 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4618 PF15397.6 EGF98800.1 - 0.46 9.9 6.9 0.69 9.3 3.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) FlaC_arch PF05377.11 EGF98800.1 - 1.4 9.4 4.2 1.1 9.6 1.1 2.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Pro_isomerase PF00160.21 EGF98802.1 - 3.9e-47 160.4 0.0 6.6e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EGF98802.1 - 2.7e-06 28.0 5.9 0.6 11.1 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat SAC3_GANP PF03399.16 EGF98803.1 - 7.5e-99 330.8 0.2 8.6e-99 330.6 0.2 1.0 1 0 0 1 1 1 1 SAC3/GANP family zf-CCHC_3 PF13917.6 EGF98806.1 - 4.6e-14 52.1 2.3 8e-14 51.3 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 EGF98806.1 - 0.015 15.7 0.9 0.015 15.7 0.9 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.23 EGF98806.1 - 0.19 11.9 2.1 0.3 11.2 2.1 1.3 1 0 0 1 1 1 0 Zinc knuckle Hist_deacetyl PF00850.19 EGF98808.1 - 8.4e-45 153.6 0.1 1.3e-44 152.9 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DAGAT PF03982.13 EGF98812.1 - 1.6e-100 335.9 0.0 2.5e-100 335.3 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 EGF98812.1 - 2.3 7.9 12.4 0.74 9.5 6.7 2.2 1 1 0 2 2 2 0 Rer1 family Vps51 PF08700.11 EGF98813.1 - 1.3e-15 57.3 1.2 2.1e-15 56.6 0.3 1.9 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 EGF98813.1 - 0.0001 21.1 0.4 0.00014 20.7 0.4 1.2 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.9 EGF98813.1 - 0.0027 17.9 1.2 0.0049 17.1 1.2 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 AATF-Che1 PF13339.6 EGF98813.1 - 0.045 14.4 0.2 0.09 13.5 0.2 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor SKA2 PF16740.5 EGF98813.1 - 0.094 12.5 0.6 0.42 10.4 0.1 2.3 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 HSBP1 PF06825.12 EGF98813.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Syntaxin-6_N PF09177.11 EGF98813.1 - 1.4 9.5 6.1 2.3 8.9 3.8 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Asp PF00026.23 EGF98814.1 - 5e-21 75.4 0.0 1.9e-20 73.5 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF98814.1 - 0.0011 19.2 0.1 0.03 14.6 0.0 2.9 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal DUF5127 PF17168.4 EGF98815.1 - 6.3e-62 209.3 0.7 9.7e-62 208.7 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EGF98815.1 - 2.6e-56 190.0 0.0 4.4e-56 189.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EGF98815.1 - 3.6e-46 157.6 0.2 6.3e-46 156.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EGF98815.1 - 8.4e-06 25.2 0.1 2.1e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 EGF98815.1 - 0.022 14.2 0.1 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term HMMR_C PF15908.5 EGF98816.1 - 0.021 15.1 0.3 0.047 14.0 0.3 1.6 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal CHDCT2 PF08074.11 EGF98816.1 - 0.093 12.9 0.8 0.13 12.4 0.8 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain XkdW PF09636.10 EGF98816.1 - 0.098 12.8 0.6 0.16 12.1 0.6 1.3 1 0 0 1 1 1 0 XkdW protein LigT_PEase PF02834.16 EGF98816.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 LigT like Phosphoesterase FAM76 PF16046.5 EGF98816.1 - 0.15 11.4 1.4 0.17 11.2 1.4 1.2 1 0 0 1 1 1 0 FAM76 protein Prominin PF05478.11 EGF98816.1 - 0.21 9.5 2.4 0.26 9.2 2.4 1.1 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 EGF98816.1 - 0.24 11.5 2.5 0.49 10.4 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BORCS6 PF10157.9 EGF98818.1 - 0.0092 16.2 3.8 0.0092 16.2 3.8 3.3 2 1 0 2 2 2 1 BLOC-1-related complex sub-unit 6 TMF_DNA_bd PF12329.8 EGF98818.1 - 0.018 15.0 1.9 0.053 13.5 0.7 2.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 EGF98818.1 - 0.029 15.0 0.3 0.12 13.0 0.3 2.1 1 0 0 1 1 1 0 SlyX DUF4200 PF13863.6 EGF98818.1 - 0.03 14.7 0.5 0.1 13.0 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Spc42p PF11544.8 EGF98818.1 - 0.032 14.2 0.5 0.13 12.2 0.5 2.1 1 0 0 1 1 1 0 Spindle pole body component Spc42p bZIP_1 PF00170.21 EGF98818.1 - 0.085 13.0 1.1 0.25 11.5 1.1 1.8 1 0 0 1 1 1 0 bZIP transcription factor EzrA PF06160.12 EGF98818.1 - 0.091 10.9 0.2 0.14 10.3 0.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DivIC PF04977.15 EGF98818.1 - 0.095 12.5 0.3 0.23 11.2 0.3 1.6 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 EGF98818.1 - 0.65 10.7 2.7 0.83 10.3 0.4 2.4 2 1 0 2 2 2 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 EGF98818.1 - 0.75 10.1 4.9 0.35 11.1 1.7 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cep57_MT_bd PF06657.13 EGF98818.1 - 1.3 9.5 7.4 0.44 11.0 1.6 3.0 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 RSS_P20 PF11757.8 EGF98818.1 - 1.4 9.4 5.8 2.9 8.4 0.3 3.2 3 0 0 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain KLRAQ PF10205.9 EGF98818.1 - 8.1 6.8 8.7 0.66 10.2 2.3 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Alpha_kinase PF02816.18 EGF98819.1 - 1.1e-30 107.1 0.1 1.8e-30 106.4 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family FlhD PF05247.13 EGF98819.1 - 0.072 13.4 0.2 0.24 11.7 0.1 1.9 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhD) Prok-E2_A PF14457.6 EGF98820.1 - 0.27 10.9 5.9 4 7.0 0.1 2.3 1 1 1 2 2 2 0 Prokaryotic E2 family A Pkinase PF00069.25 EGF98821.1 - 1e-63 215.2 0.0 1.2e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF98821.1 - 2.4e-44 151.6 0.0 3.1e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF98821.1 - 3.1e-07 29.5 0.0 5.1e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF98821.1 - 0.00026 20.4 0.0 0.00093 18.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGF98821.1 - 0.0061 15.6 0.8 1.2 7.9 0.1 2.1 2 0 0 2 2 2 2 Haspin like kinase domain FTA2 PF13095.6 EGF98821.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGF98821.1 - 0.086 12.7 0.1 0.98 9.3 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGF98821.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L29e PF01779.17 EGF98822.1 - 0.033 14.5 0.5 0.049 14.0 0.5 1.3 1 0 0 1 1 1 0 Ribosomal L29e protein family DUF4112 PF13430.6 EGF98823.1 - 1.3e-30 105.8 0.1 1.8e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Parathyroid PF01279.17 EGF98824.1 - 0.0022 18.6 1.3 0.56 10.9 0.1 3.5 1 1 2 3 3 3 1 Parathyroid hormone family FAA_hydro_N_2 PF18288.1 EGF98824.1 - 0.22 11.9 1.0 9.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 CEP19 PF14933.6 EGF98824.1 - 0.73 10.1 6.3 1.4 9.2 1.5 2.6 1 1 1 2 2 2 0 CEP19-like protein DUF2934 PF11154.8 EGF98824.1 - 2 8.1 10.3 6.6 6.5 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) BPL_N PF09825.9 EGF98825.1 - 2.3e-35 122.4 0.0 2.1e-34 119.2 0.0 2.0 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EGF98825.1 - 5.3e-19 68.4 0.0 9.1e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Trm112p PF03966.16 EGF98826.1 - 4.3e-16 59.2 0.0 7.1e-16 58.5 0.0 1.4 1 1 0 1 1 1 1 Trm112p-like protein FNIP PF05725.12 EGF98826.1 - 0.49 10.6 5.7 0.27 11.5 0.7 2.7 2 1 1 3 3 3 0 FNIP Repeat K_oxygenase PF13434.6 EGF98827.1 - 1e-86 291.2 0.1 9.8e-56 189.3 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGF98827.1 - 7.8e-05 22.7 0.0 0.0024 17.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DUF2375 PF09558.10 EGF98827.1 - 0.1 12.6 0.0 4.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2375) Spot_14 PF07084.12 EGF98828.1 - 0.016 15.4 1.3 1 9.5 0.0 2.1 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 TMA7 PF09072.10 EGF98830.1 - 0.018 15.9 0.2 0.032 15.1 0.2 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 FAR1 PF03101.15 EGF98831.1 - 0.00029 21.5 1.6 0.00064 20.4 1.6 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 EGF98831.1 - 0.064 13.7 6.4 0.15 12.5 6.4 1.9 1 1 0 1 1 1 0 Transcription factor AFT Merozoite_SPAM PF07133.11 EGF98831.1 - 0.33 10.9 15.8 0.61 10.1 15.8 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Baculo_PEP_C PF04513.12 EGF98834.1 - 0.013 15.6 1.8 0.02 14.9 1.8 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Alpha_kinase PF02816.18 EGF98836.1 - 1.3e-08 35.2 0.0 3.7e-07 30.5 0.0 2.1 1 1 1 2 2 2 2 Alpha-kinase family DUF4106 PF13388.6 EGF98837.1 - 0.013 14.8 10.1 0.024 13.9 10.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) SDA1 PF05285.12 EGF98837.1 - 0.4 10.1 15.5 0.6 9.5 15.5 1.4 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 EGF98837.1 - 0.56 8.7 13.8 0.78 8.2 13.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EGF98837.1 - 0.8 7.9 10.8 1 7.5 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EGF98837.1 - 0.87 8.9 18.6 1.5 8.1 18.6 1.4 1 0 0 1 1 1 0 BUD22 DUF2722 PF10846.8 EGF98837.1 - 0.95 8.3 17.0 1.4 7.8 17.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PT PF04886.12 EGF98837.1 - 1.3 8.6 16.4 2.5 7.7 16.4 1.5 1 0 0 1 1 1 0 PT repeat Glyco_hydro_31 PF01055.26 EGF98838.1 - 0.069 12.3 0.0 0.069 12.3 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 MFS_1 PF07690.16 EGF98841.1 - 2e-11 43.4 7.0 2.3e-11 43.2 7.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.19 EGF98841.1 - 0.00045 19.1 1.8 0.00051 18.9 0.5 1.7 1 1 0 2 2 2 1 LacY proton/sugar symporter SPT_ssu-like PF11779.8 EGF98841.1 - 0.24 11.0 4.5 0.3 10.7 2.7 2.1 1 1 1 2 2 2 0 Small subunit of serine palmitoyltransferase-like ESSS PF10183.9 EGF98841.1 - 4.2 7.6 5.5 11 6.3 0.2 2.2 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FtsX PF02687.21 EGF98841.1 - 9.2 6.8 10.9 1 9.9 2.8 2.5 2 1 0 2 2 2 0 FtsX-like permease family RNA_pol_3_Rpc31 PF11705.8 EGF98842.1 - 2.3 8.4 33.3 0.16 12.2 17.8 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2052 PF09747.9 EGF98842.1 - 6.9 6.7 25.3 5.3 7.1 15.6 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) ubiquitin PF00240.23 EGF98844.1 - 1e-34 118.1 0.4 1.2e-34 117.8 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGF98844.1 - 4.1e-16 58.6 0.6 4.9e-16 58.3 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L40e PF01020.17 EGF98844.1 - 4.2e-10 39.4 2.1 7.4e-10 38.6 2.1 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Ubiquitin_2 PF14560.6 EGF98844.1 - 2.5e-05 24.7 0.1 9e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGF98844.1 - 0.004 17.0 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGF98844.1 - 0.006 16.9 0.1 0.0081 16.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGF98844.1 - 0.0078 16.3 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGF98844.1 - 0.03 14.9 0.1 0.035 14.7 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGF98844.1 - 0.047 13.7 1.0 8.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Peroxidase_2 PF01328.17 EGF98845.1 - 2.3e-25 90.2 0.0 2.6e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 DUF89 PF01937.19 EGF98846.1 - 2.8e-30 105.5 0.0 3.2e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 ANAPC2 PF08672.11 EGF98847.1 - 1.3e-12 48.1 0.0 3.2e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 adh_short_C2 PF13561.6 EGF98850.1 - 1.2e-19 70.8 0.0 1.5e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGF98850.1 - 1.6e-12 47.3 0.0 2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Helicase_C PF00271.31 EGF98851.1 - 1e-06 29.1 0.0 2.7e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RR_TM4-6 PF06459.12 EGF98851.1 - 0.031 14.1 4.9 0.054 13.3 4.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1764 PF08576.10 EGF98851.1 - 4.3 8.3 11.2 13 6.8 11.2 1.9 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Lbh PF15317.6 EGF98853.1 - 0.061 14.2 0.8 0.17 12.7 0.2 2.1 1 1 0 1 1 1 0 Cardiac transcription factor regulator, Developmental protein Abhydrolase_6 PF12697.7 EGF98855.1 - 1.3e-24 88.1 0.0 1.7e-24 87.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGF98855.1 - 9.2e-16 58.3 0.1 3.8e-15 56.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGF98855.1 - 1.5e-11 44.0 0.2 2.2e-11 43.5 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGF98855.1 - 0.00021 21.5 0.2 0.00044 20.4 0.2 1.5 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EGF98855.1 - 0.003 17.3 0.1 0.0043 16.8 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein VirJ PF06057.11 EGF98855.1 - 0.014 15.3 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) LIDHydrolase PF10230.9 EGF98855.1 - 0.024 14.2 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF900 PF05990.12 EGF98855.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.13 EGF98855.1 - 0.27 11.1 0.9 0.7 9.7 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Syja_N PF02383.18 EGF98857.1 - 4.6e-66 223.3 0.1 7.6e-66 222.6 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain Oxysterol_BP PF01237.18 EGF98858.1 - 6.4e-22 77.9 0.0 2.5e-20 72.7 0.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein Seryl_tRNA_N PF02403.22 EGF98859.1 - 0.73 10.1 15.5 0.6 10.4 12.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-CCHC_4 PF14392.6 EGF98861.1 - 0.13 12.0 0.8 0.31 10.8 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle NAD_synthase PF02540.17 EGF98865.1 - 0.16 11.0 0.0 0.31 10.1 0.0 1.4 1 1 0 1 1 1 0 NAD synthase TT_ORF2 PF02957.15 EGF98866.1 - 0.77 10.7 5.9 0.16 12.9 2.8 1.6 2 0 0 2 2 2 0 TT viral ORF2 BPTA PF17044.5 EGF98869.1 - 0.019 14.8 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Borrelial persistence in ticks protein A Catalase PF00199.19 EGF98872.1 - 2.4e-168 560.1 0.0 3.7e-168 559.6 0.0 1.2 1 0 0 1 1 1 1 Catalase Ras PF00071.22 EGF98873.1 - 1.6e-52 177.3 0.0 1.8e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF98873.1 - 1e-21 77.4 0.0 1.4e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF98873.1 - 3.8e-09 36.2 0.0 4.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGF98873.1 - 1.9e-06 27.9 0.0 0.051 13.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGF98873.1 - 1.3e-05 24.8 0.1 0.00031 20.3 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGF98873.1 - 7.5e-05 22.8 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF98873.1 - 0.00018 21.1 0.1 0.0012 18.4 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B CbiA PF01656.23 EGF98873.1 - 0.0029 17.7 0.0 0.016 15.3 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EGF98873.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGF98873.1 - 0.026 14.1 0.1 0.058 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EGF98873.1 - 0.043 13.1 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 Septin G-alpha PF00503.20 EGF98873.1 - 0.05 12.8 0.0 0.11 11.6 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit NB-ARC PF00931.22 EGF98873.1 - 0.12 11.5 0.2 0.16 11.1 0.2 1.3 1 1 0 1 1 1 0 NB-ARC domain DAP3 PF10236.9 EGF98873.1 - 0.17 11.1 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF5102 PF17104.5 EGF98874.1 - 7.4e-30 105.0 11.5 7.4e-30 105.0 11.5 3.3 1 1 0 2 2 2 1 Domain of unknown function (DUF5102) FEZ PF07763.13 EGF98874.1 - 5.9 6.6 11.8 0.43 10.3 1.1 3.0 3 1 1 4 4 4 0 FEZ-like protein PH PF00169.29 EGF98875.1 - 4e-14 53.0 0.0 8.9e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 EGF98875.1 - 2.1e-13 49.9 0.1 3.8e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF98875.1 - 2.3e-13 49.5 0.3 5e-13 48.4 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGF98875.1 - 4.9e-09 35.7 0.0 9.6e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 EGF98875.1 - 4.2e-08 33.2 0.0 9.3e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CH PF00307.31 EGF98875.1 - 5.3e-07 29.8 0.0 2.5e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain PH_11 PF15413.6 EGF98875.1 - 1.3e-06 28.8 0.4 3.3e-06 27.5 0.4 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.30 EGF98875.1 - 6.7e-05 23.3 0.1 0.00014 22.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_9 PF15410.6 EGF98875.1 - 0.082 13.3 0.1 5.2 7.5 0.1 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain SAM_Ste50p PF09235.10 EGF98875.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif DUF4130 PF13566.6 EGF98877.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 ABC2_membrane PF01061.24 EGF98878.1 - 2.6e-74 249.2 60.2 7.4e-41 139.9 27.2 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGF98878.1 - 3e-31 108.7 0.0 3.3e-14 53.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGF98878.1 - 5.9e-31 106.2 10.4 1.1e-23 83.0 0.0 3.8 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EGF98878.1 - 1e-06 29.3 0.0 3e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EGF98878.1 - 0.00021 21.2 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 EGF98878.1 - 0.0003 20.7 0.2 0.46 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGF98878.1 - 0.0018 18.0 0.2 0.022 14.5 0.3 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGF98878.1 - 0.0025 17.9 0.2 1.6 8.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 EGF98878.1 - 0.0062 16.1 0.1 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EGF98878.1 - 0.0076 15.7 0.0 0.33 10.3 0.0 3.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 EGF98878.1 - 0.02 15.0 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGF98878.1 - 0.027 14.9 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EGF98878.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF98878.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGF98878.1 - 0.19 12.0 0.1 0.71 10.1 0.1 2.0 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 EGF98878.1 - 0.2 10.7 57.6 0.018 14.2 16.6 3.1 2 1 1 3 3 2 0 ABC-2 family transporter protein AAA_18 PF13238.6 EGF98878.1 - 0.21 12.1 0.0 0.6 10.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF853 PF05872.12 EGF98879.1 - 0.019 13.6 0.4 0.022 13.4 0.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Bap31_Bap29_C PF18035.1 EGF98879.1 - 0.17 11.9 3.7 0.3 11.1 3.7 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain SRP-alpha_N PF04086.13 EGF98879.1 - 1.2 9.0 6.3 1.4 8.8 6.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ABC2_membrane PF01061.24 EGF98880.1 - 3.8e-76 255.2 66.2 1.3e-40 139.0 29.9 2.8 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 EGF98880.1 - 1.2e-31 108.5 10.4 7.4e-25 86.7 0.0 3.7 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.27 EGF98880.1 - 9.6e-31 107.1 0.0 2.6e-14 53.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGF98880.1 - 0.00032 20.6 0.2 0.45 10.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGF98880.1 - 0.00057 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 EGF98880.1 - 0.0011 18.2 17.4 0.0011 18.2 17.4 2.8 3 0 0 3 3 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 EGF98880.1 - 0.0016 18.1 0.1 0.021 14.6 0.3 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGF98880.1 - 0.0036 17.4 0.1 2.7 8.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 EGF98880.1 - 0.0063 16.1 0.3 0.019 14.5 0.1 1.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EGF98880.1 - 0.022 14.2 0.1 1.9 7.9 0.0 3.0 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGF98880.1 - 0.031 14.7 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EGF98880.1 - 0.035 14.3 0.0 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGF98880.1 - 0.082 13.2 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF98880.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGF98880.1 - 0.17 12.2 0.0 0.62 10.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain HTH_Tnp_Tc3_2 PF01498.18 EGF98881.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Transposase SH3_2 PF07653.17 EGF98882.1 - 0.039 13.6 0.2 0.5 10.1 0.0 2.7 2 2 0 2 2 2 0 Variant SH3 domain ABC2_membrane PF01061.24 EGF98883.1 - 2.1e-76 256.0 64.6 3.9e-41 140.8 27.9 2.8 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 EGF98883.1 - 2.8e-31 107.3 10.4 9.5e-25 86.3 0.0 3.7 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.27 EGF98883.1 - 1.2e-29 103.6 0.0 5.5e-14 52.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 EGF98883.1 - 2.1e-12 47.5 0.0 6.4e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 EGF98883.1 - 0.00043 20.2 1.6 0.31 10.8 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGF98883.1 - 0.00071 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 EGF98883.1 - 0.0017 17.6 42.9 0.0036 16.4 11.9 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 EGF98883.1 - 0.0021 17.8 0.2 0.023 14.4 0.3 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGF98883.1 - 0.0052 16.9 0.1 3.7 7.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 EGF98883.1 - 0.0054 16.3 0.0 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGF98883.1 - 0.013 15.9 0.0 0.034 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 EGF98883.1 - 0.016 14.7 0.0 1.2 8.5 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 EGF98883.1 - 0.034 14.3 0.0 0.098 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGF98883.1 - 0.041 14.1 0.1 0.096 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF98883.1 - 0.19 11.4 0.1 0.38 10.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGF98883.1 - 0.39 11.0 1.0 0.82 9.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain CoA_binding PF02629.19 EGF98884.1 - 1e-29 103.1 0.1 2.6e-29 101.7 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 EGF98884.1 - 2.1e-25 89.4 0.1 3.2e-25 88.7 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EGF98884.1 - 4e-08 33.1 0.1 9.4e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EGF98884.1 - 1.4e-05 25.6 0.0 6.1e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 EGF98884.1 - 0.021 15.7 0.0 0.064 14.1 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DCP2 PF05026.13 EGF98885.1 - 1.6e-26 92.5 0.1 2.8e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EGF98885.1 - 1.9e-17 63.6 0.0 3.1e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Sugar_tr PF00083.24 EGF98887.1 - 1.3e-109 367.1 27.7 1.5e-109 366.9 27.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGF98887.1 - 3.8e-21 75.4 43.4 5.6e-15 55.1 11.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGF98887.1 - 8.7 4.5 15.3 0.22 9.8 5.3 2.7 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family CLN3 PF02487.17 EGF98888.1 - 2.2e-121 405.7 12.3 4.6e-121 404.6 12.3 1.5 1 0 0 1 1 1 1 CLN3 protein DUF1218 PF06749.12 EGF98891.1 - 0.34 11.4 2.1 5.9 7.5 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Aldose_epim PF01263.20 EGF98892.1 - 3.9e-27 95.3 0.0 5.9e-27 94.7 0.0 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase Sgf11 PF08209.11 EGF98893.1 - 7.5e-06 25.4 0.2 1.1e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) THRAP3_BCLAF1 PF15440.6 EGF98893.1 - 0.032 13.3 12.6 0.055 12.5 12.6 1.3 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Orthopox_A36R PF05950.11 EGF98893.1 - 0.043 14.0 1.0 0.043 14.0 1.0 1.6 2 0 0 2 2 2 0 Orthopoxvirus A36R protein Presenilin PF01080.17 EGF98893.1 - 6.7 5.4 4.8 7.3 5.2 4.8 1.2 1 0 0 1 1 1 0 Presenilin Mating_C PF12737.7 EGF98894.1 - 0.16 11.2 3.9 0.55 9.4 0.5 2.1 1 1 1 2 2 2 0 C-terminal domain of homeodomain 1 Erv26 PF04148.13 EGF98897.1 - 5.7e-58 196.1 14.1 6.7e-58 195.9 14.1 1.2 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Peptidase_C24 PF03510.14 EGF98899.1 - 0.08 13.4 0.0 0.23 11.9 0.0 1.7 2 0 0 2 2 2 0 2C endopeptidase (C24) cysteine protease family RL10P_insert PF17777.1 EGF98900.1 - 4.2e-22 77.9 0.1 7.8e-22 77.1 0.1 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EGF98900.1 - 1.2e-19 70.3 0.0 2.7e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Tim44 PF04280.15 EGF98900.1 - 0.071 13.2 0.4 0.11 12.5 0.1 1.5 2 0 0 2 2 2 0 Tim44-like domain DUF4078 PF13300.6 EGF98902.1 - 1.6e-09 37.9 4.4 6.4e-09 36.0 4.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4078) DZR PF12773.7 EGF98903.1 - 1.9 8.6 11.6 8.5 6.5 11.7 2.1 1 1 1 2 2 2 0 Double zinc ribbon RRXRR PF14239.6 EGF98904.1 - 0.066 13.1 2.2 0.072 12.9 2.2 1.0 1 0 0 1 1 1 0 RRXRR protein HORMA PF02301.18 EGF98905.1 - 1.8e-15 57.1 0.0 2.2e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EGF98905.1 - 0.019 15.0 0.1 0.034 14.1 0.1 1.5 1 1 0 1 1 1 0 Autophagy-related protein 101 bacHORMA_2 PF18173.1 EGF98905.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial HORMA domain 2 O-FucT PF10250.9 EGF98906.1 - 7.5e-09 35.7 0.0 1.2e-05 25.2 0.0 2.1 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Phage_1_1 PF08200.11 EGF98906.1 - 0.019 15.4 0.3 0.06 13.8 0.3 1.9 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein Nup88 PF10168.9 EGF98907.1 - 3.1e-07 28.6 0.7 0.00047 18.1 0.0 2.6 2 1 0 2 2 2 2 Nuclear pore component CorA PF01544.18 EGF98907.1 - 2.1 7.6 4.6 2.5 7.4 0.2 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Lebercilin PF15619.6 EGF98907.1 - 6.4 6.4 8.5 11 5.6 2.4 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HEAT_2 PF13646.6 EGF98908.1 - 7e-27 93.7 2.1 8.4e-14 51.7 0.1 3.3 2 1 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 EGF98908.1 - 6.5e-22 75.9 0.9 0.0018 18.8 0.0 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EGF98908.1 - 7.8e-09 35.1 4.4 0.13 12.6 0.0 5.6 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.23 EGF98908.1 - 8.6e-05 22.4 0.1 0.024 14.7 0.0 3.5 2 1 1 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGF98908.1 - 0.002 18.6 2.9 0.86 10.2 0.0 4.5 4 2 0 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.20 EGF98909.1 - 7.1e-18 64.5 0.2 7.5e-18 64.4 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.22 EGF98909.1 - 9.2e-08 31.7 0.2 0.00078 19.5 0.0 2.4 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 EGF98909.1 - 0.00033 21.0 0.0 0.00059 20.2 0.0 1.4 1 1 0 1 1 1 1 HEAT repeats Cnd1 PF12717.7 EGF98909.1 - 0.034 14.2 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 FANCI_S4 PF14678.6 EGF98909.1 - 0.036 13.2 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 FANCI solenoid 4 Adaptin_N PF01602.20 EGF98910.1 - 1.4e-17 63.5 0.2 1.5e-17 63.4 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Sugar_tr PF00083.24 EGF98912.1 - 1.3e-110 370.4 26.8 1.5e-110 370.2 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGF98912.1 - 6.1e-22 78.0 35.3 2.8e-14 52.8 6.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 EGF98912.1 - 0.036 14.3 2.0 0.036 14.3 2.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) DUF697 PF05128.12 EGF98912.1 - 0.12 12.1 1.2 0.39 10.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF697) Cytochrom_B_C PF00032.17 EGF98912.1 - 0.19 12.0 3.0 0.17 12.2 0.7 2.2 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD STIMATE PF12400.8 EGF98913.1 - 2.4e-31 108.9 3.9 3.8e-31 108.2 3.9 1.3 1 0 0 1 1 1 1 STIMATE family TraQ PF09679.10 EGF98914.1 - 0.75 9.7 1.9 1.7 8.6 0.1 2.0 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) GATase_4 PF13230.6 EGF98915.1 - 0.04 12.8 0.1 0.049 12.5 0.1 1.1 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Peptidase_C48 PF02902.19 EGF98916.1 - 3.4e-05 23.8 0.1 0.00013 21.9 0.1 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain ORC6 PF05460.13 EGF98916.1 - 0.77 9.0 10.4 0.98 8.6 10.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ndc1_Nup PF09531.10 EGF98916.1 - 4 6.0 8.5 4.6 5.8 8.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DNA_pol_A_exo1 PF01612.20 EGF98920.1 - 0.15 11.8 0.2 10 5.8 0.1 2.4 1 1 0 2 2 2 0 3'-5' exonuclease Erp_C PF06780.11 EGF98921.1 - 0.087 12.8 2.0 0.21 11.6 0.3 2.0 1 1 1 2 2 2 0 Erp protein C-terminus DNA_pol3_theta PF06440.11 EGF98921.1 - 0.1 12.3 0.3 0.6 9.8 0.1 2.2 1 1 1 2 2 2 0 DNA polymerase III, theta subunit Erp_C PF06780.11 EGF98922.1 - 1.3 9.0 4.8 0.73 9.8 0.6 2.5 2 1 1 3 3 3 0 Erp protein C-terminus zf-CCHC PF00098.23 EGF98924.1 - 0.059 13.5 2.1 0.089 12.9 2.1 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 EGF98924.1 - 0.26 11.2 1.7 0.69 9.8 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle WD40 PF00400.32 EGF98925.1 - 2.4e-07 31.3 2.6 0.3 12.1 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 EGF98925.1 - 0.0019 16.9 1.2 0.21 10.2 0.2 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytomega_UL84 PF06284.11 EGF98925.1 - 0.18 10.2 2.1 0.29 9.6 2.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Lactamase_B_2 PF12706.7 EGF98926.1 - 5.9e-07 29.2 0.0 7.3e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 EGF98926.1 - 0.1 11.7 0.3 3.5 6.6 0.7 2.0 1 1 1 2 2 2 0 cAMP phosphodiesterases class-II DUF4856 PF16148.5 EGF98926.1 - 0.1 11.6 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4856) Lactamase_B PF00753.27 EGF98926.1 - 0.17 11.9 1.4 0.3 11.1 1.4 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily LIM_bind PF01803.16 EGF98927.1 - 8.7e-56 189.1 0.0 8.7e-56 189.1 0.0 9.2 5 3 1 6 6 6 1 LIM-domain binding protein PIP5K PF01504.18 EGF98928.1 - 8.4e-37 126.9 0.1 1.5e-28 99.8 0.1 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase MFS_1 PF07690.16 EGF98932.1 - 2.6e-17 62.8 14.4 6.9e-16 58.1 14.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF98932.1 - 1e-11 44.4 7.6 1e-11 44.4 7.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter WYL_3 PF18488.1 EGF98933.1 - 0.084 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 WYL domain Ank_2 PF12796.7 EGF98934.1 - 1e-18 67.7 0.2 1.3e-09 38.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGF98934.1 - 4.7e-15 55.3 0.2 2.1e-05 24.7 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGF98934.1 - 2.3e-14 53.5 3.2 4.6e-07 30.3 0.1 4.3 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF98934.1 - 4.9e-13 48.0 0.2 0.00013 22.1 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGF98934.1 - 1.9e-08 34.4 0.3 0.0021 18.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EGF98934.1 - 9e-06 25.5 0.1 0.0002 21.2 0.1 2.7 1 1 0 1 1 1 1 KilA-N domain Exonuc_VII_L PF02601.15 EGF98934.1 - 1 8.8 4.0 1.9 8.0 4.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIA PF03153.13 EGF98935.1 - 0.64 9.9 24.0 1 9.3 24.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HMGL-like PF00682.19 EGF98936.1 - 9.8e-41 140.0 0.0 1.3e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 HMGL-like CRAL_TRIO PF00650.20 EGF98938.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 CRAL/TRIO domain Kinetochor_Ybp2 PF08568.10 EGF98940.1 - 0.0026 16.3 1.4 0.022 13.3 0.1 2.0 1 1 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Ost4 PF10215.9 EGF98942.1 - 2e-13 49.9 0.5 2.8e-13 49.4 0.5 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase GPI-anchored PF10342.9 EGF98943.1 - 0.0035 18.1 0.1 0.04 14.7 0.0 2.5 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4469 PF14734.6 EGF98943.1 - 0.065 13.4 0.0 12 6.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4469) with IG-like fold DnaJ PF00226.31 EGF98944.1 - 6.9e-16 58.1 0.1 2.3e-15 56.4 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 EGF98944.1 - 5.6e-08 32.3 0.0 9.8e-07 28.2 0.0 2.2 1 1 0 1 1 1 1 Sec63 Brl domain COX17 PF05051.13 EGF98945.1 - 1.1e-20 73.8 3.4 1.4e-20 73.4 3.4 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 EGF98945.1 - 0.088 13.1 0.5 0.21 11.8 0.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) CRAL_TRIO_N PF03765.15 EGF98946.1 - 1.3e-09 38.1 0.3 6.5e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain SMRP1 PF15181.6 EGF98946.1 - 0.04 13.5 0.1 0.083 12.5 0.1 1.4 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 Kinesin PF00225.23 EGF98947.1 - 1.1e-89 300.7 0.0 1.4e-89 300.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF98947.1 - 2.8e-16 59.8 0.0 7.7e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding DUF87 PF01935.17 EGF98947.1 - 8.6 6.4 7.5 4.9 7.2 1.3 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain DUF2457 PF10446.9 EGF98949.1 - 0.2 10.8 2.1 0.26 10.4 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RabGAP-TBC PF00566.18 EGF98950.1 - 4.3e-12 46.2 1.3 5.4e-12 45.8 1.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LIX1 PF14954.6 EGF98950.1 - 0.0039 16.5 0.0 0.0045 16.3 0.0 1.1 1 0 0 1 1 1 1 Limb expression 1 ABC_tran_CTD PF16326.5 EGF98953.1 - 0.02 15.1 2.9 0.079 13.2 0.1 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain Peptidase_S46 PF10459.9 EGF98953.1 - 0.029 13.1 2.2 0.036 12.7 2.2 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF1515 PF07439.11 EGF98953.1 - 0.077 13.0 0.2 0.2 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Msg2_C PF12373.8 EGF98953.1 - 0.097 12.1 0.1 0.23 10.9 0.1 1.6 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal Fez1 PF06818.15 EGF98953.1 - 0.38 11.2 6.7 0.64 10.4 6.4 1.6 1 1 0 1 1 1 0 Fez1 NUC194 PF08163.12 EGF98954.1 - 0.038 12.9 0.2 0.047 12.6 0.2 1.1 1 0 0 1 1 1 0 NUC194 domain DUF3195 PF11424.8 EGF98954.1 - 0.071 13.2 0.2 0.17 12.0 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3195) DUF2170 PF09938.9 EGF98954.1 - 0.2 11.4 0.0 0.23 11.1 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) Cwf_Cwc_15 PF04889.12 EGF98959.1 - 1.1 8.9 14.4 0.21 11.3 7.2 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CH PF00307.31 EGF98961.1 - 0.058 13.6 0.0 3.5 7.8 0.0 2.8 2 1 0 3 3 3 0 Calponin homology (CH) domain HMG_box PF00505.19 EGF98961.1 - 0.079 13.4 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box SRP-alpha_N PF04086.13 EGF98961.1 - 0.79 9.6 13.9 1.6 8.6 13.9 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal LRR_4 PF12799.7 EGF98962.1 - 0.12 12.8 1.8 10 6.7 0.0 3.5 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGF98963.1 - 0.00028 20.7 0.2 0.001 18.9 0.2 2.0 1 1 0 1 1 1 1 F-box-like DUF3716 PF12511.8 EGF98964.1 - 0.68 10.0 8.8 2.6 8.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3716) DUF2691 PF10903.8 EGF98965.1 - 0.086 12.7 0.0 0.095 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2691) Alpha_kinase PF02816.18 EGF98966.1 - 6.9e-06 26.3 0.0 8.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Neural_ProG_Cyt PF06567.11 EGF98966.1 - 0.15 12.3 0.9 18 5.6 0.3 2.1 2 0 0 2 2 2 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain CDC27 PF09507.10 EGF98967.1 - 0.87 8.9 8.1 1.3 8.4 8.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SOG2 PF10428.9 EGF98967.1 - 7.2 5.7 22.9 8.8 5.4 22.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SDA1 PF05285.12 EGF98968.1 - 2.3 7.6 6.5 6.9 6.0 6.5 1.8 1 0 0 1 1 1 0 SDA1 zf-RING_UBOX PF13445.6 EGF98968.1 - 5.5 7.1 5.5 4.6 7.4 0.1 3.1 3 0 0 3 3 3 0 RING-type zinc-finger FliJ PF02050.16 EGF98969.1 - 0.0052 17.0 0.3 0.011 16.0 0.3 1.4 1 0 0 1 1 1 1 Flagellar FliJ protein DUF3450 PF11932.8 EGF98969.1 - 0.011 15.1 0.9 0.018 14.3 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 EGF98969.1 - 0.46 11.0 4.3 0.58 10.7 1.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CdvA PF18822.1 EGF98969.1 - 0.52 10.1 9.4 0.094 12.5 5.3 1.8 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF4988 PF16378.5 EGF98969.1 - 0.56 9.8 2.8 0.53 9.9 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function SlyX PF04102.12 EGF98969.1 - 2.4 8.8 6.4 0.65 10.6 2.1 2.2 2 0 0 2 2 2 0 SlyX XhlA PF10779.9 EGF98969.1 - 5.7 7.2 6.7 1.3 9.3 2.1 2.2 2 0 0 2 2 2 0 Haemolysin XhlA NAM-associated PF14303.6 EGF98970.1 - 0.052 14.3 0.1 0.052 14.3 0.1 2.7 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain Ras PF00071.22 EGF98973.1 - 3.6e-58 195.7 0.1 4.3e-58 195.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF98973.1 - 1.3e-20 73.8 0.0 1.9e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF98973.1 - 8.4e-09 35.1 0.0 1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF98973.1 - 1.5e-05 24.6 0.0 3e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGF98973.1 - 3.8e-05 23.7 0.2 0.093 12.6 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGF98973.1 - 0.0015 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EGF98973.1 - 0.0041 17.1 0.0 0.0077 16.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EGF98973.1 - 0.015 14.9 0.0 0.033 13.7 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Ser_hydrolase PF06821.13 EGF98973.1 - 0.067 13.0 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase ATP_bind_1 PF03029.17 EGF98973.1 - 0.12 12.2 1.4 1.3 8.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PFK PF00365.20 EGF98974.1 - 5.5e-185 613.3 0.3 3.5e-104 348.1 0.4 2.7 2 1 0 2 2 2 2 Phosphofructokinase TgMIC1 PF11476.8 EGF98974.1 - 0.028 14.2 0.1 10 5.9 0.0 2.7 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Sod_Cu PF00080.20 EGF98975.1 - 1.1e-15 58.1 0.0 2.1e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 EGF98975.1 - 0.027 15.4 3.0 0.44 11.5 3.0 2.5 1 1 0 1 1 1 0 CHRD domain Proteasome PF00227.26 EGF98976.1 - 2.6e-46 157.5 0.0 3.3e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGF98976.1 - 2.6e-14 52.6 0.2 4.5e-14 51.8 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SurE PF01975.17 EGF98977.1 - 6.8e-32 110.8 0.1 8.5e-32 110.5 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE SBP_bac_10 PF07596.11 EGF98978.1 - 0.0024 17.9 0.2 0.0034 17.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1559) RRM_1 PF00076.22 EGF98978.1 - 0.0081 16.0 0.0 0.4 10.5 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UBP PF02148.19 EGF98979.1 - 0.041 14.2 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Apolipoprotein PF01442.18 EGF98980.1 - 0.023 14.5 3.6 0.11 12.4 1.2 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain LXG PF04740.12 EGF98980.1 - 0.03 14.0 1.8 0.059 13.1 1.8 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily Focal_AT PF03623.13 EGF98980.1 - 0.044 13.8 1.9 1 9.4 0.7 2.5 2 0 0 2 2 2 0 Focal adhesion targeting region DUF4455 PF14643.6 EGF98980.1 - 0.069 11.8 0.3 0.13 10.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Baculo_PEP_C PF04513.12 EGF98980.1 - 0.14 12.2 2.1 0.35 10.9 2.1 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 EGF98980.1 - 0.42 11.2 5.1 0.54 10.9 0.3 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 EGF98980.1 - 1.1 9.3 5.2 5.6 7.0 0.8 2.7 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) LRR_4 PF12799.7 EGF98981.1 - 7.5e-40 134.3 35.7 9.7e-09 35.4 2.9 6.6 5 1 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF98981.1 - 5.9e-25 86.8 38.1 8e-09 35.1 1.5 7.0 5 2 2 7 7 7 4 Leucine rich repeat LRR_9 PF14580.6 EGF98981.1 - 5.6e-18 65.0 12.4 6.6e-08 32.3 1.3 3.9 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 EGF98981.1 - 7.5e-08 31.8 26.9 2.1 8.6 0.1 10.7 9 2 3 12 12 12 5 Leucine Rich repeat LRR_1 PF00560.33 EGF98981.1 - 3.3e-05 23.8 32.1 3.5 8.5 0.0 10.7 9 1 0 9 9 9 1 Leucine Rich Repeat LRR_2 PF07723.13 EGF98981.1 - 0.081 13.6 1.4 7.2 7.5 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_5 PF13306.6 EGF98981.1 - 0.13 12.2 0.7 1.7 8.7 0.1 2.6 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) GrpE PF01025.19 EGF98982.1 - 0.15 11.7 1.0 1.3 8.7 0.0 2.7 4 0 0 4 4 4 0 GrpE AvrM-A PF18241.1 EGF98983.1 - 5.8e-37 127.3 4.0 1.4e-36 126.1 4.0 1.7 1 0 0 1 1 1 1 Flax-rust effector AvrM-A AvrM-A PF18241.1 EGF98984.1 - 5.1e-59 198.9 10.5 5.1e-59 198.9 10.5 2.3 2 0 0 2 2 2 1 Flax-rust effector AvrM-A AvrM_N PF18247.1 EGF98984.1 - 6.7e-32 109.2 0.5 4.3e-31 106.6 0.3 2.4 2 0 0 2 2 2 1 Flax-rust effector AvrM N-terminal domain DEAD PF00270.29 EGF98986.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase HTH_ABP1_N PF18107.1 EGF98986.1 - 0.096 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain FAM199X PF15814.5 EGF98987.1 - 7.1 5.6 7.9 10 5.0 7.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X NDUF_B7 PF05676.13 EGF98988.1 - 7.9e-32 108.8 5.4 9.8e-32 108.5 5.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EGF98988.1 - 0.0031 17.5 3.7 0.0037 17.3 3.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Rsa3 PF14615.6 EGF98989.1 - 5.1e-05 22.7 0.3 0.00018 21.0 0.1 2.1 2 1 0 2 2 2 1 Ribosome-assembly protein 3 SR-25 PF10500.9 EGF98989.1 - 0.016 14.9 8.5 0.023 14.3 8.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 EGF98989.1 - 0.055 14.2 7.5 0.097 13.4 7.5 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF305 PF03713.13 EGF98989.1 - 0.11 12.6 0.0 0.41 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF305) MRI PF15325.6 EGF98989.1 - 1 10.5 6.3 2.1 9.5 6.3 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection UMPH-1 PF05822.12 EGF98993.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) mRNA_cap_enzyme PF01331.19 EGF98994.1 - 1.4e-48 165.3 0.0 2.6e-48 164.4 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EGF98994.1 - 7e-26 91.0 0.1 1.1e-25 90.3 0.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EGF98994.1 - 2.9e-07 30.4 0.0 0.00068 19.3 0.0 3.0 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EGF98994.1 - 0.0019 18.5 0.1 0.0037 17.6 0.0 1.6 2 0 0 2 2 2 1 RNA ligase DUF4420 PF14390.6 EGF98994.1 - 0.13 11.4 0.3 0.86 8.8 0.5 2.0 2 0 0 2 2 2 0 Putative PD-(D/E)XK family member, (DUF4420) Alpha_kinase PF02816.18 EGF98995.1 - 2.3e-10 40.9 0.3 3.9e-10 40.1 0.3 1.3 1 0 0 1 1 1 1 Alpha-kinase family ORC6 PF05460.13 EGF98997.1 - 0.47 9.7 7.1 0.65 9.2 7.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) N36 PF11438.8 EGF98998.1 - 0.042 13.6 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) NUP50 PF08911.11 EGF98998.1 - 2 9.1 7.1 0.17 12.5 1.4 2.0 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) USP7_C2 PF14533.6 EGF98999.1 - 0.015 15.0 0.3 0.022 14.4 0.3 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal DUF1515 PF07439.11 EGF98999.1 - 0.83 9.7 6.8 0.92 9.6 1.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) DUF445 PF04286.12 EGF99000.1 - 0.11 12.3 17.1 0.19 11.5 17.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4250 PF14056.6 EGF99000.1 - 0.18 11.7 0.3 0.18 11.7 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Pex19 PF04614.12 EGF99000.1 - 1.5 8.6 13.2 0.82 9.4 10.5 2.0 1 1 0 1 1 1 0 Pex19 protein family ANAPC2 PF08672.11 EGF99000.1 - 2.2 8.8 8.4 1.2 9.7 0.2 4.3 5 2 2 7 7 7 0 Anaphase promoting complex (APC) subunit 2 FliE PF02049.18 EGF99000.1 - 2.3 8.4 6.9 3.3 7.9 3.3 3.0 2 2 1 3 3 3 0 Flagellar hook-basal body complex protein FliE Fib_alpha PF08702.10 EGF99000.1 - 4 7.6 22.0 2 8.6 13.2 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Glutaredoxin PF00462.24 EGF99001.1 - 2.7e-16 59.5 0.2 3.7e-16 59.1 0.2 1.2 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 EGF99001.1 - 0.00017 21.5 0.1 0.00017 21.5 0.1 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EGF99001.1 - 0.00062 20.2 0.5 0.00089 19.7 0.5 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 EGF99001.1 - 0.0032 17.8 0.3 0.0048 17.3 0.3 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 EGF99001.1 - 0.0047 16.9 0.1 0.0065 16.5 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin domain MtrA PF04208.14 EGF99001.1 - 0.0073 16.0 0.1 0.01 15.5 0.1 1.2 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit A Thioredoxin PF00085.20 EGF99001.1 - 0.028 14.4 0.1 0.031 14.3 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 EGF99001.1 - 0.041 14.1 0.2 0.17 12.1 0.2 1.9 1 1 0 1 1 1 0 Thioredoxin-like GST_N_3 PF13417.6 EGF99001.1 - 0.046 14.1 0.0 0.058 13.8 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EGF99002.1 - 6.6e-18 64.7 0.1 9.3e-18 64.2 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 EGF99002.1 - 0.0001 22.7 0.5 0.00015 22.2 0.4 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 EGF99002.1 - 0.00025 21.0 0.1 0.00026 20.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EGF99002.1 - 0.00045 20.1 0.0 0.00046 20.1 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 EGF99002.1 - 0.0013 18.7 0.1 0.002 18.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.6 EGF99002.1 - 0.006 16.7 0.1 0.015 15.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EGF99002.1 - 0.0088 16.0 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_4 PF13462.6 EGF99002.1 - 0.02 15.1 1.3 0.14 12.3 0.5 2.0 1 1 1 2 2 2 0 Thioredoxin DUF836 PF05768.14 EGF99002.1 - 0.059 13.8 0.4 0.087 13.2 0.4 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 EGF99002.1 - 0.13 12.7 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain UQ_con PF00179.26 EGF99003.1 - 1.8e-19 69.7 0.0 2.5e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PLA2_B PF01735.18 EGF99004.1 - 9.2e-65 218.9 0.1 2.1e-43 148.5 0.6 2.4 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.22 EGF99004.1 - 0.0014 18.9 1.9 0.0028 17.9 0.9 1.9 2 1 0 2 2 2 1 Patatin-like phospholipase PMBR PF09373.10 EGF99004.1 - 0.22 11.8 1.5 3 8.2 0.1 2.5 2 0 0 2 2 2 0 Pseudomurein-binding repeat MFS_1 PF07690.16 EGF99005.1 - 7.4e-27 94.2 23.5 7.4e-27 94.2 23.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF99005.1 - 0.0024 16.8 17.1 0.0068 15.3 16.0 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Polysacc_deac_1 PF01522.21 EGF99006.1 - 1.3e-28 99.4 0.0 1.9e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase PTPlike_phytase PF14566.6 EGF99007.1 - 9.4e-07 29.1 0.0 2.6e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EGF99007.1 - 1.6e-06 28.0 0.0 3.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGF99007.1 - 0.00074 19.5 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGF99007.1 - 0.011 15.4 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CDKN3 PF05706.12 EGF99007.1 - 0.12 12.0 0.0 0.88 9.2 0.0 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Nudix_N_2 PF14803.6 EGF99008.1 - 0.38 10.7 2.0 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 Nudix N-terminal FHA PF00498.26 EGF99009.1 - 1.4e-14 54.1 0.0 3.6e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGF99009.1 - 0.00016 22.0 0.2 0.00062 20.0 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain APC1_C PF18122.1 EGF99009.1 - 0.17 11.8 3.4 0.79 9.6 3.3 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain DUF4500 PF14937.6 EGF99009.1 - 0.26 11.3 1.4 0.71 9.9 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) DUF1664 PF07889.12 EGF99009.1 - 1.6 8.8 22.7 1.4 9.0 1.5 4.2 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) Sec20 PF03908.13 EGF99009.1 - 1.9 8.4 18.7 0.16 11.9 8.8 3.6 3 1 1 4 4 4 0 Sec20 DUF948 PF06103.11 EGF99009.1 - 5.5 7.3 12.4 0.56 10.5 3.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 EGF99012.1 - 0.16 12.3 4.1 0.38 11.1 3.5 2.0 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BLOC1_2 PF10046.9 EGF99013.1 - 0.021 15.1 3.0 0.92 9.8 0.6 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 EGF99013.1 - 0.043 14.2 4.8 2.3 8.6 0.6 2.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 EGF99013.1 - 0.066 13.8 5.2 0.24 12.0 2.0 3.1 2 1 0 2 2 2 0 SlyX Lzipper-MIP1 PF14389.6 EGF99013.1 - 0.14 12.5 5.3 5 7.5 0.6 3.1 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 TMCO5 PF14992.6 EGF99013.1 - 0.46 10.0 6.5 0.63 9.6 5.4 1.7 1 1 0 1 1 1 0 TMCO5 family Tropomyosin_1 PF12718.7 EGF99013.1 - 0.56 10.4 9.1 1.3 9.1 1.4 3.0 2 1 1 3 3 3 0 Tropomyosin like FlaC_arch PF05377.11 EGF99013.1 - 3.1 8.3 7.1 8.6 6.8 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) MatE PF01554.18 EGF99014.1 - 5.6e-53 178.9 22.1 3.3e-27 95.1 6.3 2.6 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EGF99014.1 - 0.0083 16.2 9.6 0.0083 16.2 9.6 3.7 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF4396 PF14342.6 EGF99015.1 - 0.19 12.1 4.2 0.67 10.3 4.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) FA_desaturase PF00487.24 EGF99016.1 - 3.1e-24 86.2 17.1 5.4e-24 85.4 15.1 1.9 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 EGF99016.1 - 5.2e-17 61.0 0.4 9.5e-17 60.2 0.4 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Pacifastin_I PF05375.13 EGF99017.1 - 4.9 7.0 10.0 4.2 7.2 0.2 3.3 3 1 1 4 4 4 0 Pacifastin inhibitor (LCMII) RRM_1 PF00076.22 EGF99019.1 - 0.00016 21.4 0.0 0.33 10.8 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_FP PF03258.14 EGF99019.1 - 0.26 11.5 0.0 0.44 10.7 0.0 1.3 1 0 0 1 1 1 0 Baculovirus FP protein AA_permease_2 PF13520.6 EGF99020.1 - 3.5e-33 115.1 34.4 4.7e-33 114.7 34.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGF99020.1 - 4.4e-13 48.7 30.3 6.2e-13 48.2 30.3 1.1 1 0 0 1 1 1 1 Amino acid permease COG4 PF08318.12 EGF99022.1 - 0.084 11.9 0.2 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 COG4 transport protein COG4 PF08318.12 EGF99023.1 - 0.00031 20.0 0.1 0.00083 18.5 0.1 1.6 1 1 0 1 1 1 1 COG4 transport protein PRP38_assoc PF12871.7 EGF99026.1 - 2.1 9.0 7.9 1.5 9.5 0.1 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3195 PF11424.8 EGF99027.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) DUF2170 PF09938.9 EGF99027.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) NUC194 PF08163.12 EGF99027.1 - 0.15 11.0 0.4 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 NUC194 domain Sec34 PF04136.15 EGF99031.1 - 0.091 12.6 2.9 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Sec34-like family Nop14 PF04147.12 EGF99031.1 - 1.5 7.0 19.6 0.013 13.8 11.7 1.5 2 0 0 2 2 2 0 Nop14-like family SR-25 PF10500.9 EGF99031.1 - 9.8 5.7 23.5 22 4.5 23.5 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Phage_integrase PF00589.22 EGF99033.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family PGI PF00342.19 EGF99035.1 - 2.6e-230 765.1 0.2 3e-230 764.9 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase AA_permease_2 PF13520.6 EGF99036.1 - 8e-28 97.4 35.0 1.3e-27 96.7 35.0 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGF99036.1 - 1.4e-06 27.2 29.1 2.5e-06 26.3 29.2 1.4 1 1 0 1 1 1 1 Amino acid permease SpoVAB PF13782.6 EGF99036.1 - 0.042 14.1 3.8 0.072 13.4 1.5 2.5 2 0 0 2 2 2 0 Stage V sporulation protein AB Ribosomal_L4 PF00573.22 EGF99037.1 - 1.8e-40 138.7 0.2 3e-40 138.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EGF99037.1 - 1e-26 92.8 0.8 1e-26 92.8 0.8 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Peptidase_C12 PF01088.21 EGF99041.1 - 2.2e-53 181.1 0.0 2.5e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 TFIIA_gamma_N PF02268.16 EGF99042.1 - 5.4e-23 80.7 0.0 7.4e-23 80.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 EGF99042.1 - 2.7e-19 69.0 0.0 3.8e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit BPL_N PF09825.9 EGF99043.1 - 0.62 9.1 3.0 1 8.4 3.0 1.5 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Cyt-b5 PF00173.28 EGF99044.1 - 1.5e-15 57.1 0.0 2.6e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 EGF99044.1 - 2.5e-13 50.5 23.0 4.4e-13 49.7 23.0 1.5 1 0 0 1 1 1 1 Fatty acid desaturase DTHCT PF08070.11 EGF99044.1 - 0.15 12.8 0.8 0.27 12.0 0.8 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region Glyco_transf_15 PF01793.16 EGF99049.1 - 1.2e-112 376.4 5.7 1.4e-112 376.2 5.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RRM_1 PF00076.22 EGF99050.1 - 9.9e-29 99.0 0.0 2.8e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGF99050.1 - 0.0026 17.3 0.0 1.9 8.1 0.0 2.1 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGF99050.1 - 0.0087 16.1 0.0 0.052 13.6 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.8 EGF99050.1 - 0.078 13.1 0.0 0.84 9.8 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 GRP PF07172.11 EGF99050.1 - 7 7.4 15.3 0.14 12.8 5.2 2.4 2 1 0 2 2 2 0 Glycine rich protein family DDE_3 PF13358.6 EGF99051.1 - 1.9e-06 27.7 0.0 4.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3349 PF11829.8 EGF99051.1 - 0.085 13.6 0.2 0.18 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) DUF5058 PF16481.5 EGF99052.1 - 0.038 13.7 7.0 0.077 12.7 1.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5058) PhoR PF11808.8 EGF99052.1 - 1.1 9.8 0.0 1.1 9.8 0.0 3.6 5 0 0 5 5 5 0 Phosphate regulon sensor protein PhoR Polysacc_deac_1 PF01522.21 EGF99053.1 - 1.7e-29 102.2 0.0 2.7e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGF99053.1 - 0.0018 17.6 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF4379 PF14311.6 EGF99053.1 - 1.4 9.3 7.1 0.14 12.5 2.2 1.9 2 0 0 2 2 2 0 Probable Zinc-ribbon domain Lipase_GDSL PF00657.22 EGF99054.1 - 0.00012 22.1 0.6 0.00018 21.6 0.6 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Stealth_CR2 PF11380.8 EGF99055.1 - 1.3e-12 47.9 1.2 2.3e-08 34.2 0.1 3.4 2 1 1 3 3 3 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 EGF99055.1 - 1.1e-10 41.3 0.1 2.3e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 EF-hand_1 PF00036.32 EGF99055.1 - 0.0014 18.0 0.1 0.0034 16.8 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EGF99055.1 - 0.0052 16.2 0.1 0.013 15.0 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGF99055.1 - 0.17 11.9 0.1 0.17 11.9 0.1 2.3 3 0 0 3 3 3 0 EF-hand domain DCP1 PF06058.13 EGF99056.1 - 9.4e-32 109.4 0.0 1.9e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Dcp1-like decapping family Peptidase_S49 PF01343.18 EGF99057.1 - 5.8e-39 133.5 0.0 1.9e-25 89.6 0.0 2.5 2 0 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.23 EGF99057.1 - 0.028 14.3 0.4 0.13 12.2 0.3 2.1 2 0 0 2 2 2 0 Clp protease SDH_sah PF01972.16 EGF99057.1 - 0.12 11.4 0.1 0.23 10.4 0.1 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DDRGK PF09756.9 EGF99058.1 - 0.71 9.4 11.5 0.77 9.3 11.5 1.1 1 0 0 1 1 1 0 DDRGK domain DUF5398 PF17376.2 EGF99059.1 - 0.04 14.5 0.7 0.11 13.1 0.7 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5398) MlaC PF05494.12 EGF99059.1 - 0.043 13.6 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 MlaC protein DUF676 PF05057.14 EGF99060.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF676 PF05057.14 EGF99061.1 - 0.03 13.8 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGF99061.1 - 0.099 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase SMN PF06003.12 EGF99061.1 - 0.22 10.7 0.1 0.34 10.1 0.1 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Peptidase_M22 PF00814.25 EGF99062.1 - 4.4e-72 243.0 0.0 5.1e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family BcrAD_BadFG PF01869.20 EGF99062.1 - 0.063 12.8 0.1 0.6 9.5 0.0 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Trehalose_PPase PF02358.16 EGF99063.1 - 4e-07 29.4 0.0 0.00032 19.9 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.12 EGF99063.1 - 0.0029 17.4 0.0 0.13 12.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_M29 PF02073.15 EGF99063.1 - 0.093 11.5 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Gal4_dimer PF03902.13 EGF99063.1 - 0.19 11.9 1.7 8.6 6.6 0.0 2.7 3 0 0 3 3 3 0 Gal4-like dimerisation domain JmjC PF02373.22 EGF99064.1 - 1.2e-42 145.0 0.7 1.7e-42 144.4 0.7 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 EGF99064.1 - 2.2e-11 43.5 10.1 2.3e-11 43.4 7.8 2.1 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 EGF99064.1 - 0.091 13.1 9.1 0.27 11.6 7.9 2.4 2 1 1 3 3 3 0 Ring finger domain Zf_RING PF16744.5 EGF99064.1 - 0.25 11.5 5.1 0.74 10.0 5.1 1.9 1 1 0 1 1 1 0 KIAA1045 RING finger PHD_2 PF13831.6 EGF99064.1 - 0.35 10.4 6.7 0.067 12.8 2.2 2.2 3 0 0 3 3 3 0 PHD-finger COesterase PF00135.28 EGF99065.1 - 1.2e-66 225.7 0.0 2e-66 224.9 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGF99065.1 - 0.023 14.5 0.1 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 EGF99066.1 - 7.8e-64 216.4 0.0 2.3e-63 214.8 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 EGF99067.1 - 8.1e-63 213.0 0.0 5.2e-62 210.4 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family E1-E2_ATPase PF00122.20 EGF99068.1 - 1.4e-46 158.3 1.4 1.4e-46 158.3 1.4 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGF99068.1 - 2.6e-33 116.1 0.2 2.6e-33 116.1 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGF99068.1 - 6.9e-23 80.9 0.0 9.1e-11 42.0 0.0 3.1 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EGF99068.1 - 7.2e-08 32.5 1.4 1.5e-05 24.9 0.4 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EGF99068.1 - 0.11 12.7 0.1 0.97 9.6 0.0 2.7 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase NUDIX PF00293.28 EGF99069.1 - 0.0015 18.6 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 2 NUDIX domain COesterase PF00135.28 EGF99071.1 - 2.4e-78 264.3 0.0 3.1e-78 263.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGF99071.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGF99071.1 - 0.018 14.5 0.3 0.049 13.1 0.3 1.6 1 1 1 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.28 EGF99072.1 - 1.3e-75 255.3 0.0 1.7e-75 254.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGF99072.1 - 0.0063 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EGF99073.1 - 5.7e-75 253.1 0.0 7.9e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EGF99073.1 - 0.056 12.9 0.2 0.097 12.1 0.2 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGF99073.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Trehalose_PPase PF02358.16 EGF99074.1 - 4.6e-39 133.9 1.1 2.8e-28 98.6 0.0 2.2 1 1 1 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.12 EGF99074.1 - 2.5e-06 27.4 0.0 3.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pox_Ag35 PF03286.14 EGF99077.1 - 0.079 12.8 3.4 0.14 11.9 3.4 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 EGF99082.1 - 1.9e-13 49.7 0.0 2.3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein DEAD PF00270.29 EGF99087.1 - 2.9e-44 150.9 0.2 5.5e-44 150.0 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF99087.1 - 8.6e-33 113.0 0.1 3.7e-32 111.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF99087.1 - 0.00015 21.8 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGF99087.1 - 0.00097 19.5 0.2 0.019 15.3 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGF99087.1 - 0.0041 16.9 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EGF99087.1 - 0.016 14.7 0.1 0.024 14.2 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EGF99087.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 EGF99087.1 - 0.19 11.7 0.7 0.53 10.2 0.1 2.2 2 2 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.6 EGF99087.1 - 0.25 11.6 0.8 1.3 9.3 0.8 2.0 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.23 EGF99091.1 - 9.6e-30 103.5 0.3 1.2e-29 103.1 0.3 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGF99091.1 - 2.8e-07 30.5 0.0 3.5e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGF99091.1 - 2.7e-05 24.2 0.0 3.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGF99092.1 - 7.8e-12 45.5 0.0 1.1e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Alpha_kinase PF02816.18 EGF99093.1 - 1.6e-34 119.7 1.5 1.8e-34 119.5 1.5 1.0 1 0 0 1 1 1 1 Alpha-kinase family SOG2 PF10428.9 EGF99094.1 - 0.75 8.9 11.1 0.99 8.5 11.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein NOA36 PF06524.12 EGF99094.1 - 7.5 5.8 16.7 12 5.1 16.7 1.2 1 0 0 1 1 1 0 NOA36 protein CxC1 PF18802.1 EGF99096.1 - 2.2e-24 85.6 0.7 4e-24 84.8 0.7 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGF99096.1 - 1.5e-18 67.3 0.0 9.7e-18 64.6 0.0 2.0 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EGF99096.1 - 0.00012 22.2 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CDC50 PF03381.15 EGF99098.1 - 9.1e-97 323.9 0.0 1.4e-96 323.3 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family FCH PF00611.23 EGF99099.1 - 2e-09 37.6 9.7 3.6e-08 33.6 9.7 2.8 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Fzo_mitofusin PF04799.13 EGF99099.1 - 0.24 11.0 4.4 0.21 11.1 1.4 2.2 1 1 1 2 2 2 0 fzo-like conserved region ATP-synt_ab PF00006.25 EGF99100.1 - 1.7e-105 351.4 0.0 2.4e-105 350.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EGF99100.1 - 1.2e-44 151.0 0.0 2.2e-44 150.2 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EGF99100.1 - 3.1e-14 53.2 2.3 7.2e-14 52.1 2.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NopRA1 PF16201.5 EGF99102.1 - 0.091 12.3 0.4 14 5.1 0.0 3.7 3 1 1 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Retrotran_gag_2 PF14223.6 EGF99103.1 - 0.00027 20.6 0.1 0.00048 19.8 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGF99103.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type NatB_MDM20 PF09797.9 EGF99104.1 - 1.4e-55 188.8 13.3 2.9e-55 187.8 13.3 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Val_tRNA-synt_C PF10458.9 EGF99104.1 - 0.008 16.4 4.1 1.2 9.5 0.0 3.4 3 0 0 3 3 3 2 Valyl tRNA synthetase tRNA binding arm TPR_16 PF13432.6 EGF99104.1 - 0.054 14.1 0.0 0.34 11.6 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF99104.1 - 0.059 13.6 0.1 0.27 11.5 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGF99104.1 - 0.073 13.2 0.0 8.4 6.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGF99104.1 - 0.15 12.6 0.1 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Ras PF00071.22 EGF99105.1 - 2.3e-58 196.4 0.5 2.8e-58 196.1 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF99105.1 - 2.6e-37 127.7 0.3 4.3e-37 127.0 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF99105.1 - 1.3e-16 60.6 0.5 1.5e-16 60.4 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF99105.1 - 3.8e-07 29.8 0.2 2.5e-06 27.2 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGF99105.1 - 2.4e-06 27.1 0.1 3.7e-06 26.5 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGF99105.1 - 4.4e-05 23.5 0.1 7.1e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF99105.1 - 4.5e-05 23.4 0.1 0.019 14.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGF99105.1 - 0.00011 21.7 0.3 0.00017 21.0 0.3 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EGF99105.1 - 0.00082 18.9 0.3 0.023 14.2 0.3 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EGF99105.1 - 0.0045 16.8 0.1 0.016 15.0 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FlgH PF02107.16 EGF99105.1 - 0.058 13.0 1.0 0.083 12.5 1.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein TniB PF05621.11 EGF99105.1 - 0.089 12.2 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EGF99105.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_S8 PF00082.22 EGF99107.1 - 0.035 13.4 0.0 0.81 8.9 0.0 2.3 2 0 0 2 2 2 0 Subtilase family YqzE PF14038.6 EGF99107.1 - 0.62 10.1 0.0 0.62 10.1 0.0 2.8 2 0 0 2 2 2 0 YqzE-like protein DUF2058 PF09831.9 EGF99107.1 - 5.8 7.0 11.1 3.2 7.9 1.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) COG4 PF08318.12 EGF99109.1 - 1.5e-09 37.4 0.0 1.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 COG4 transport protein CCDC32 PF14989.6 EGF99111.1 - 0.097 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing 32 zn-ribbon_14 PF16503.5 EGF99111.1 - 0.32 10.5 1.4 0.63 9.6 1.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon LUC7 PF03194.15 EGF99112.1 - 6.2e-62 209.5 5.6 1.2e-61 208.6 5.6 1.3 1 1 0 1 1 1 1 LUC7 N_terminus DUF3418 PF11898.8 EGF99112.1 - 0.0049 15.6 0.8 0.006 15.3 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) HGD-D PF06050.13 EGF99112.1 - 0.0064 16.3 0.1 0.0074 16.1 0.1 1.1 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component Mt_ATP-synt_D PF05873.12 EGF99112.1 - 0.12 12.2 1.0 0.24 11.2 0.1 1.9 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Seryl_tRNA_N PF02403.22 EGF99112.1 - 1.9 8.8 6.9 24 5.2 6.9 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RabGAP-TBC PF00566.18 EGF99115.1 - 1.3e-37 129.5 0.3 2.1e-37 128.9 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Hist_deacetyl PF00850.19 EGF99116.1 - 9.9e-82 274.8 0.0 1.3e-81 274.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain SHMT PF00464.19 EGF99117.1 - 1.4e-12 46.9 0.0 1.5e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase PSI_PsaH PF03244.14 EGF99119.1 - 0.17 11.4 1.1 0.32 10.5 1.1 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI MTHFR PF02219.17 EGF99120.1 - 2.5e-90 302.7 0.0 3.7e-90 302.1 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase FAM60A PF15396.6 EGF99124.1 - 0.14 12.1 6.4 0.2 11.6 6.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TMEM215 PF15746.5 EGF99124.1 - 7.5 5.9 6.9 5 6.5 2.4 2.1 1 1 1 2 2 2 0 TMEM215 family Ac76 PF05814.11 EGF99124.1 - 10 6.2 5.5 14 5.7 0.3 2.6 1 1 1 2 2 2 0 Orf76 (Ac76) Tail_P2_I PF09684.10 EGF99125.1 - 0.056 13.4 0.1 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Phage tail protein (Tail_P2_I) Cullin PF00888.22 EGF99126.1 - 1.3e-07 30.7 0.0 4.5e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Cullin family Flg_hook PF02120.16 EGF99126.1 - 0.048 13.6 0.1 0.096 12.6 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK CmcI PF04989.12 EGF99128.1 - 0.045 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase ICMT PF04140.14 EGF99130.1 - 0.098 13.1 0.2 0.18 12.3 0.2 1.5 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family E1-E2_ATPase PF00122.20 EGF99131.1 - 0.064 12.8 1.8 0.15 11.6 1.8 1.7 1 0 0 1 1 1 0 E1-E2 ATPase LIDHydrolase PF10230.9 EGF99132.1 - 4.2e-49 167.5 0.1 6.4e-49 166.9 0.1 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 EGF99132.1 - 2.4e-06 27.4 0.0 3.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EGF99132.1 - 8.2e-06 25.7 0.1 1.6e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EGF99132.1 - 0.00066 19.0 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGF99132.1 - 0.0068 17.0 0.0 0.0091 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 EGF99132.1 - 0.016 14.4 0.1 0.026 13.7 0.1 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.13 EGF99132.1 - 0.089 12.6 0.1 0.36 10.7 0.0 2.0 3 0 0 3 3 3 0 Serine hydrolase TniB PF05621.11 EGF99132.1 - 0.09 12.2 0.0 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein Lipase PF00151.19 EGF99132.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Lipase LIDHydrolase PF10230.9 EGF99133.1 - 1.4e-23 83.9 0.5 1.2e-21 77.5 0.2 2.2 1 1 1 2 2 2 2 Lipid-droplet associated hydrolase PGAP1 PF07819.13 EGF99133.1 - 0.00011 22.0 0.1 0.00029 20.6 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EGF99133.1 - 0.033 13.5 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LCAT PF02450.15 EGF99133.1 - 0.053 12.7 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Chlorophyllase2 PF12740.7 EGF99133.1 - 0.073 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme SLATT_6 PF18169.1 EGF99133.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 CBF PF03914.17 EGF99133.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 CBF/Mak21 family Abhydrolase_6 PF12697.7 EGF99133.1 - 0.15 12.6 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sfi1 PF08457.10 EGF99134.1 - 8.8e-11 41.0 68.5 2.3e-09 36.4 33.5 4.2 1 1 2 4 4 4 4 Sfi1 spindle body protein PHD20L1_u1 PF16660.5 EGF99134.1 - 0.043 14.6 0.2 0.098 13.4 0.2 1.5 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 F-box-like PF12937.7 EGF99135.1 - 0.009 15.9 3.8 0.015 15.2 0.9 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 EGF99135.1 - 0.066 13.1 1.4 0.14 12.1 0.4 2.1 2 0 0 2 2 2 0 F-box domain DEAD PF00270.29 EGF99135.1 - 0.18 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 EGF99138.1 - 1.7e-05 24.6 9.8 1.7e-05 24.6 9.8 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF99138.1 - 2.3e-05 24.3 9.2 2.3e-05 24.3 9.2 3.4 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGF99138.1 - 0.00013 21.8 9.5 0.00013 21.8 9.5 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGF99138.1 - 0.00029 20.9 10.1 0.00029 20.9 10.1 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGF99138.1 - 0.00039 20.3 14.3 0.0019 18.1 11.7 2.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_6 PF14835.6 EGF99138.1 - 0.00041 20.2 4.4 0.00041 20.2 4.4 2.5 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 EGF99138.1 - 0.0036 17.1 4.4 0.0036 17.1 4.4 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 EGF99138.1 - 0.026 14.8 15.9 0.026 14.8 15.9 3.1 2 1 1 3 3 3 0 Ring finger domain zf-WRNIP1_ubi PF18279.1 EGF99138.1 - 0.035 14.7 7.4 0.52 11.1 0.4 3.8 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Rad50_zn_hook PF04423.14 EGF99138.1 - 0.32 10.9 3.7 27 4.7 0.1 3.7 3 0 0 3 3 3 0 Rad50 zinc hook motif Prefoldin_3 PF13758.6 EGF99138.1 - 0.58 10.3 3.6 0.87 9.7 2.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit UBZ_FAAP20 PF15750.5 EGF99138.1 - 2.1 8.4 12.7 0.37 10.8 0.2 4.0 4 0 0 4 4 4 0 Ubiquitin-binding zinc-finger Sgf11 PF08209.11 EGF99138.1 - 5.8 6.6 8.6 0.14 11.8 0.3 2.6 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-Nse PF11789.8 EGF99139.1 - 3.2e-10 39.7 2.4 6.8e-10 38.6 2.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 EGF99139.1 - 7.6e-08 32.1 6.3 1.4e-07 31.2 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF99139.1 - 4.4e-05 23.3 6.8 8.8e-05 22.3 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGF99139.1 - 0.00018 21.6 6.6 0.00018 21.6 6.6 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGF99139.1 - 0.00023 21.4 8.2 0.00054 20.2 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGF99139.1 - 0.0035 17.3 8.2 0.0081 16.2 8.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.20 EGF99139.1 - 0.06 13.1 5.4 0.12 12.1 5.4 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_10 PF16685.5 EGF99139.1 - 0.17 12.1 5.5 0.33 11.1 5.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 EGF99139.1 - 0.35 10.8 11.1 18 5.3 11.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 EGF99139.1 - 0.52 10.2 6.9 1.2 9.0 6.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF99139.1 - 0.52 10.3 10.9 1.3 9.0 10.9 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGF99139.1 - 3.6 7.5 7.1 7.4 6.5 7.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4666 PF15697.5 EGF99139.1 - 8.2 7.2 7.9 4.6 8.0 5.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) p450 PF00067.22 EGF99140.1 - 4.5e-68 230.1 0.0 6.3e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CDC45 PF02724.14 EGF99142.1 - 0.43 8.8 5.7 0.53 8.5 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein ACPS PF01648.20 EGF99144.1 - 1.7e-09 37.8 1.0 3.2e-09 36.9 1.0 1.5 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EGF99144.1 - 0.0049 17.0 0.4 2.9 8.1 0.0 2.6 3 0 0 3 3 3 2 4'-phosphopantetheinyl transferase N-terminal domain Glyco_hydro_71 PF03659.14 EGF99146.1 - 9.7e-62 208.9 4.1 1.9e-61 208.0 4.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 FXMRP1_C_core PF12235.8 EGF99147.1 - 0.16 12.6 11.4 0.19 12.3 11.4 1.1 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal bVLRF1 PF18826.1 EGF99150.1 - 1.5e-08 34.6 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor DUF883 PF05957.13 EGF99152.1 - 1.7e-05 25.4 53.2 0.27 11.9 5.6 6.0 1 1 5 6 6 6 5 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EGF99152.1 - 0.00031 21.2 66.0 8.7 7.0 4.6 7.0 1 1 2 3 3 3 2 YtxH-like protein ApoO PF09769.9 EGF99152.1 - 0.16 11.9 14.1 15 5.5 0.0 5.1 1 1 2 4 4 4 0 Apolipoprotein O Apolipoprotein PF01442.18 EGF99152.1 - 0.33 10.8 43.3 2 8.2 21.5 3.4 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EGF99154.1 - 2.5e-05 24.8 50.8 0.28 11.8 6.5 5.9 1 1 4 5 5 5 4 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EGF99154.1 - 0.00015 22.3 63.7 0.0098 16.4 16.3 6.9 1 1 3 4 4 4 2 YtxH-like protein ApoO PF09769.9 EGF99154.1 - 0.15 12.1 13.4 13 5.8 0.0 4.9 1 1 1 3 3 3 0 Apolipoprotein O Apolipoprotein PF01442.18 EGF99154.1 - 0.98 9.3 42.3 2.7 7.8 22.8 3.2 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain PfkB PF00294.24 EGF99155.1 - 6.8e-65 219.3 0.0 1.1e-64 218.7 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Abhydrolase_1 PF00561.20 EGF99156.1 - 2e-16 60.4 0.0 5.3e-15 55.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGF99156.1 - 5.3e-12 45.5 0.0 7.4e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGF99156.1 - 2.3e-08 34.9 0.0 2.7e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGF99156.1 - 0.00021 21.0 0.0 0.0016 18.1 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF915 PF06028.11 EGF99156.1 - 0.0043 16.4 0.0 0.034 13.5 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.16 EGF99156.1 - 0.011 15.6 0.0 1.5 8.6 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 EGF99156.1 - 0.052 13.3 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Myb_DNA-bind_7 PF15963.5 EGF99162.1 - 3.1e-22 78.3 0.2 6.1e-22 77.3 0.2 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EGF99162.1 - 1.9e-10 40.8 0.0 6.6e-10 39.0 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF99162.1 - 0.00017 21.7 0.7 0.00034 20.8 0.0 2.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGF99162.1 - 0.059 13.6 0.1 0.059 13.6 0.1 1.7 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 RNA_pol_Rpc34 PF05158.12 EGF99164.1 - 1.2e-74 251.7 5.9 7.5e-70 235.9 4.1 3.1 3 0 0 3 3 3 3 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 EGF99164.1 - 7.9e-05 22.7 0.1 0.00018 21.6 0.1 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TrmB PF01978.19 EGF99164.1 - 8.5e-05 22.4 0.1 0.003 17.4 0.0 3.0 4 0 0 4 4 4 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 EGF99164.1 - 0.016 15.1 0.1 0.048 13.6 0.1 1.8 1 0 0 1 1 1 0 MarR family HTH_36 PF13730.6 EGF99164.1 - 0.021 14.8 0.4 0.049 13.6 0.4 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 EGF99164.1 - 0.042 14.2 0.2 0.17 12.2 0.1 2.0 2 0 0 2 2 2 0 Transcriptional regulator PadR PF03551.14 EGF99164.1 - 0.043 13.8 0.1 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family HxlR PF01638.17 EGF99164.1 - 0.092 12.6 0.1 0.29 11.0 0.1 1.9 2 0 0 2 2 2 0 HxlR-like helix-turn-helix RPA_C PF08784.11 EGF99164.1 - 0.43 11.3 3.6 0.44 11.2 0.2 2.3 1 1 1 2 2 2 0 Replication protein A C terminal Tetraspanin PF00335.20 EGF99165.1 - 0.15 11.7 6.9 0.28 10.9 6.9 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF3509 PF12021.8 EGF99165.1 - 0.16 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) DUF308 PF03729.13 EGF99165.1 - 0.82 10.0 13.8 18 5.8 10.7 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) UBZ_FAAP20 PF15750.5 EGF99165.1 - 1.8 8.6 10.0 0.2 11.6 3.6 2.7 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger CAP PF00188.26 EGF99166.1 - 1e-17 65.1 0.6 6.4e-17 62.6 0.6 2.1 1 1 0 1 1 1 1 Cysteine-rich secretory protein family DUF4778 PF16008.5 EGF99166.1 - 0.021 14.9 0.2 0.034 14.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Peptidase_S49_N PF08496.10 EGF99166.1 - 0.18 11.9 3.4 0.27 11.3 3.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3959 PF13105.6 EGF99166.1 - 0.28 10.6 3.3 0.4 10.1 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) NARP1 PF12569.8 EGF99166.1 - 7.5 5.3 7.9 11 4.8 7.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-RING_2 PF13639.6 EGF99169.1 - 6.2e-12 45.7 10.2 8.8e-12 45.2 10.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGF99169.1 - 8.7e-07 29.1 13.6 3e-05 24.2 13.6 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGF99169.1 - 1.3e-06 28.1 11.2 2e-06 27.5 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGF99169.1 - 7.8e-06 25.6 6.7 1.1e-05 25.2 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF99169.1 - 1.4e-05 25.0 3.8 1.4e-05 25.0 3.8 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGF99169.1 - 4.9e-05 23.1 11.1 7.4e-05 22.5 11.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGF99169.1 - 5.6e-05 22.8 11.5 0.00012 21.8 11.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EGF99169.1 - 0.00032 20.6 8.7 0.00046 20.1 8.7 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGF99169.1 - 0.011 15.7 5.7 0.042 13.9 5.8 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 EGF99169.1 - 0.032 14.6 7.7 0.044 14.1 7.7 1.2 1 0 0 1 1 1 0 RING-like domain CTU2 PF10288.9 EGF99169.1 - 0.21 11.9 1.7 1.2 9.4 1.7 2.0 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 2-oxoacid_dh PF00198.23 EGF99170.1 - 7.2e-57 192.5 0.0 8.5e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DNA_pol_phi PF04931.13 EGF99171.1 - 2.7 6.0 12.0 3.4 5.7 12.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EGF99171.1 - 8.2 4.5 11.9 8.8 4.4 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 EGF99171.1 - 8.8 5.0 6.7 9.6 4.9 6.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5490 PF17593.2 EGF99172.1 - 0.28 11.2 2.1 0.86 9.7 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5490) API5 PF05918.11 EGF99172.1 - 3 6.5 5.7 4.7 5.9 5.7 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) 2-oxoacid_dh PF00198.23 EGF99173.1 - 1.5e-73 247.1 0.0 1.9e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGF99173.1 - 2.7e-18 65.6 3.0 3.2e-18 65.3 0.9 2.2 2 1 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EGF99173.1 - 1.4e-13 50.9 0.2 3.4e-13 49.7 0.2 1.7 1 0 0 1 1 1 1 e3 binding domain Mitofilin PF09731.9 EGF99173.1 - 0.064 12.1 1.3 0.087 11.6 1.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein BIR PF00653.21 EGF99174.1 - 4e-09 37.0 1.1 2e-07 31.6 0.3 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain FATC PF02260.20 EGF99177.1 - 1.9e-05 24.4 1.5 2.8e-05 23.9 0.4 2.0 2 0 0 2 2 2 1 FATC domain Mod_r PF07200.13 EGF99177.1 - 0.12 12.5 1.2 0.37 10.9 0.1 2.3 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein FXMRP1_C_core PF12235.8 EGF99178.1 - 0.16 12.6 6.6 0.15 12.7 5.9 1.3 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal Strabismus PF06638.11 EGF99178.1 - 0.51 8.9 2.4 0.57 8.8 2.4 1.0 1 0 0 1 1 1 0 Strabismus protein RAP1 PF07218.11 EGF99178.1 - 0.52 8.5 6.9 0.61 8.3 6.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MDFI PF15316.6 EGF99179.1 - 0.2 11.7 3.1 0.27 11.3 3.1 1.2 1 0 0 1 1 1 0 MyoD family inhibitor DTHCT PF08070.11 EGF99179.1 - 1.6 9.5 14.7 1.3 9.8 12.9 1.6 1 1 1 2 2 2 0 DTHCT (NUC029) region SRP-alpha_N PF04086.13 EGF99179.1 - 4.2 7.2 12.0 5 6.9 12.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zf-RING_2 PF13639.6 EGF99180.1 - 5.4e-12 45.8 6.2 9.6e-12 45.0 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF99180.1 - 2.7e-10 39.9 5.3 4.9e-10 39.1 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGF99180.1 - 7.8e-07 28.7 2.7 1.9e-06 27.5 2.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EGF99180.1 - 4.6e-06 26.4 3.1 6.4e-06 25.9 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGF99180.1 - 8.4e-06 26.0 8.1 7e-05 23.0 8.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGF99180.1 - 9.7e-06 25.5 2.4 2.9e-05 24.0 0.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGF99180.1 - 1.8e-05 24.5 5.4 3e-05 23.8 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGF99180.1 - 0.00086 19.3 1.2 0.0018 18.3 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGF99180.1 - 0.0022 17.9 2.6 0.0035 17.3 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGF99180.1 - 0.012 15.5 5.0 0.036 13.9 4.8 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGF99180.1 - 0.071 13.3 1.0 0.12 12.5 1.0 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 EGF99180.1 - 0.16 11.6 1.7 0.28 10.8 1.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EGF99180.1 - 3.1 8.0 5.4 6.5 7.0 5.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING HLH PF00010.26 EGF99181.1 - 0.0026 17.7 0.0 0.0064 16.4 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain YppG PF14179.6 EGF99181.1 - 5.2 7.8 15.5 0.046 14.4 2.4 3.4 3 1 0 3 3 3 0 YppG-like protein FXMRP1_C_core PF12235.8 EGF99181.1 - 6.8 7.3 8.6 1.1 10.0 1.0 2.9 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Nucleotid_trans PF03407.16 EGF99182.1 - 0.07 13.1 0.0 0.095 12.7 0.0 1.3 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase ANAPC8 PF04049.13 EGF99182.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 Retrotran_gag_2 PF14223.6 EGF99183.1 - 9.9e-10 38.2 0.1 1.9e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Flavi_NS5 PF00972.20 EGF99183.1 - 0.03 12.5 0.0 0.04 12.1 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase DUF2833 PF11090.8 EGF99185.1 - 0.047 14.1 0.0 1 9.8 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2833) MRPL52 PF18699.1 EGF99186.1 - 0.15 12.3 4.1 12 6.2 4.5 2.2 2 0 0 2 2 2 0 Mitoribosomal protein mL52 DUF4407 PF14362.6 EGF99186.1 - 0.53 9.6 3.0 0.87 8.9 3.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ddrB-ParB PF18763.1 EGF99186.1 - 0.62 10.2 4.4 0.93 9.6 0.4 2.1 2 0 0 2 2 2 0 ddrB-like ParB superfamily domain SET PF00856.28 EGF99188.1 - 9.8e-11 42.3 0.0 1.3e-09 38.7 0.0 1.9 1 1 0 1 1 1 1 SET domain IRF PF00605.17 EGF99189.1 - 0.022 15.0 1.7 0.077 13.3 1.7 1.9 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor MSP1a PF11670.8 EGF99190.1 - 0.075 12.3 3.4 0.1 11.9 3.4 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Sugar_tr PF00083.24 EGF99194.1 - 4.1e-122 408.3 24.7 6.2e-122 407.7 24.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGF99194.1 - 4.2e-20 72.0 74.9 3e-18 65.9 42.9 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Pex24p PF06398.11 EGF99194.1 - 0.052 12.5 0.1 0.089 11.8 0.1 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin MFS_3 PF05977.13 EGF99194.1 - 2.4 6.4 15.7 0.078 11.4 6.4 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.24 EGF99195.1 - 7.9e-124 413.9 23.5 1.1e-123 413.5 23.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGF99195.1 - 9.5e-19 67.5 43.7 3.5e-14 52.5 14.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex24p PF06398.11 EGF99195.1 - 0.069 12.1 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DEAD PF00270.29 EGF99197.1 - 2.8e-28 98.9 0.0 5.3e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF99197.1 - 2.9e-26 92.0 0.1 6.9e-26 90.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EGF99197.1 - 0.03 14.7 0.0 0.51 10.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain COX5A PF02284.16 EGF99198.1 - 1.3e-18 66.9 0.1 1.4e-18 66.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va FACT-Spt16_Nlob PF14826.6 EGF99198.1 - 0.042 13.7 0.0 0.042 13.7 0.0 1.0 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain DUF1857 PF08982.11 EGF99198.1 - 0.12 12.2 0.0 0.13 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) MIP PF00230.20 EGF99199.1 - 6.7e-16 58.7 12.5 1.6e-15 57.5 12.5 1.6 1 1 0 1 1 1 1 Major intrinsic protein Peptidase_U57 PF05582.12 EGF99200.1 - 0.088 12.1 0.0 6.8 5.9 0.0 2.1 2 0 0 2 2 2 0 YabG peptidase U57 F-box-like PF12937.7 EGF99201.1 - 1.7e-09 37.4 0.6 3.5e-09 36.4 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGF99201.1 - 9.8e-09 34.9 0.1 2.2e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain SUB1_ProdP9 PF18213.1 EGF99202.1 - 0.12 12.3 0.9 0.31 10.9 0.7 1.8 1 1 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Pox_VLTF3 PF04947.14 EGF99205.1 - 0.019 14.7 4.8 0.026 14.2 0.2 2.3 1 1 1 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like DUF3292 PF11696.8 EGF99205.1 - 0.13 10.7 4.8 0.16 10.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF4776 PF16003.5 EGF99205.1 - 0.77 8.7 10.7 1.1 8.1 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Z1 PF10593.9 EGF99205.1 - 4.3 6.8 8.1 3.5 7.1 5.9 1.8 1 1 0 1 1 1 0 Z1 domain DUF3984 PF13136.6 EGF99206.1 - 0.06 12.7 0.2 0.067 12.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF3535 PF12054.8 EGF99206.1 - 0.1 11.8 0.1 0.11 11.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) EcKinase PF02958.20 EGF99207.1 - 0.051 12.9 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 EGF99209.1 - 1.5e-62 210.6 1.3 2.4e-62 209.9 0.0 2.0 2 1 0 2 2 2 1 RIO1 family APH PF01636.23 EGF99209.1 - 0.0095 15.9 0.3 1.2 9.0 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF4149 PF13664.6 EGF99210.1 - 9e-23 80.5 2.5 1.7e-22 79.7 2.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) DUF3278 PF11683.8 EGF99210.1 - 0.11 12.6 0.3 4.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Sugar_tr PF00083.24 EGF99212.1 - 1.8e-126 422.6 15.2 2.1e-126 422.4 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGF99212.1 - 1.5e-18 66.9 36.1 3.8e-12 45.8 17.4 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3446 PF11928.8 EGF99214.1 - 0.57 10.5 7.2 2.3 8.6 7.2 2.1 1 0 0 1 1 1 0 Early growth response N-terminal domain Syntaphilin PF15290.6 EGF99214.1 - 3.8 7.1 9.3 14 5.2 0.2 2.2 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp FAS_I_H PF18314.1 EGF99217.1 - 3.8e-08 33.2 0.0 4.4e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Apolipoprotein PF01442.18 EGF99219.1 - 0.0051 16.7 0.1 0.0095 15.8 0.1 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain NLBH PF05211.12 EGF99219.1 - 0.02 14.4 1.4 0.2 11.2 0.4 2.2 2 0 0 2 2 2 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) ComGF PF15980.5 EGF99219.1 - 0.053 13.9 2.2 0.16 12.4 2.2 1.8 1 0 0 1 1 1 0 Putative Competence protein ComGF PIN_8 PF18476.1 EGF99219.1 - 0.5 10.2 8.5 0.027 14.3 2.6 1.9 2 0 0 2 2 2 0 PIN like domain HDV_ag PF01517.18 EGF99220.1 - 0.17 11.7 3.0 1.4 8.7 2.7 2.1 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen GST_N PF02798.20 EGF99221.1 - 4.9e-17 62.0 0.1 1.4e-16 60.5 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGF99221.1 - 2.5e-15 56.5 0.1 5.3e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGF99221.1 - 1.2e-12 47.9 0.5 2.2e-12 47.0 0.1 1.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGF99221.1 - 1.7e-11 44.3 0.0 4.8e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGF99221.1 - 2.4e-09 37.5 0.0 4.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGF99221.1 - 2.3e-06 27.6 0.0 4.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3785 PF12653.7 EGF99221.1 - 0.082 13.0 0.3 0.24 11.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3785) DUF2046 PF09755.9 EGF99222.1 - 3.6e-09 36.3 13.2 7.7e-09 35.2 9.9 2.2 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) SYCE1 PF15233.6 EGF99222.1 - 0.0014 18.7 5.4 0.0027 17.8 5.4 1.4 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 V_ATPase_I PF01496.19 EGF99222.1 - 2.5 5.9 3.5 3.5 5.4 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Frag1 PF10277.9 EGF99223.1 - 6e-26 91.3 13.1 6e-26 91.3 13.1 2.4 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family DUF2183 PF09949.9 EGF99224.1 - 1.2e-29 102.6 0.1 8.2e-29 99.9 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF3439 PF11921.8 EGF99224.1 - 0.53 10.2 8.9 2 8.4 8.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TMEM135_C_rich PF15982.5 EGF99226.1 - 4.2e-05 24.2 0.3 0.0019 18.8 0.3 2.3 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 EGF99226.1 - 0.081 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family LRR_6 PF13516.6 EGF99227.1 - 1.2e-05 25.0 12.0 0.68 10.1 0.0 6.1 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 EGF99227.1 - 0.0073 16.7 3.8 26 5.9 1.3 5.6 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 EGF99227.1 - 0.024 15.0 16.4 12 6.5 0.8 5.4 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) NOA36 PF06524.12 EGF99227.1 - 7.7 5.7 5.6 13 5.0 5.6 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EGF99227.1 - 9.9 4.2 11.7 14 3.7 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 EGF99228.1 - 5.8e-56 189.8 0.0 6.5e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF99228.1 - 1.8e-31 109.4 0.0 2.1e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF99228.1 - 0.00029 20.3 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGF99228.1 - 0.00048 19.2 0.0 0.0012 17.9 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGF99228.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF99228.1 - 0.04 13.8 0.0 0.086 12.7 0.0 1.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGF99228.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ILVD_EDD PF00920.21 EGF99232.1 - 1.3e-208 693.8 0.3 1.6e-208 693.6 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family EAP30 PF04157.16 EGF99233.1 - 4.6e-31 107.9 0.0 6.8e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EGF99233.1 - 5.5e-21 74.5 0.0 1.2e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 EGF99233.1 - 7.9e-05 21.9 12.1 0.002 17.4 2.4 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF3209 PF11483.8 EGF99233.1 - 0.063 13.7 0.3 0.12 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) SKA1 PF07160.12 EGF99233.1 - 0.078 12.8 0.8 0.16 11.8 0.8 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DZR PF12773.7 EGF99233.1 - 0.2 11.7 4.0 1.8 8.7 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon CCDC24 PF15669.5 EGF99233.1 - 0.2 11.5 4.2 0.36 10.7 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Vps36-NZF-N PF16988.5 EGF99233.1 - 0.28 10.6 11.8 0.13 11.7 3.3 3.5 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EGF99233.1 - 1.9 8.6 10.8 2.5 8.2 1.5 2.7 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger PAP2_3 PF14378.6 EGF99237.1 - 1.9e-26 93.0 12.1 1.9e-26 93.0 12.1 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EGF99237.1 - 4e-10 39.6 4.4 4e-10 39.6 4.4 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EGF99237.1 - 0.013 16.0 11.7 0.013 16.0 6.1 3.0 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF3096 PF11295.8 EGF99237.1 - 5.4 6.8 6.0 33 4.2 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) zf-C2H2 PF00096.26 EGF99238.1 - 5.9e-08 32.8 9.5 0.00043 20.6 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF99238.1 - 9.5e-05 22.9 9.1 0.021 15.6 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGF99238.1 - 0.0051 17.2 0.5 0.0051 17.2 0.5 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 EGF99238.1 - 0.008 15.9 0.7 0.008 15.9 0.7 1.9 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-met PF12874.7 EGF99238.1 - 0.014 15.8 6.1 0.11 12.9 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGF99238.1 - 0.024 14.9 6.9 0.23 11.8 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EGF99238.1 - 0.057 13.3 0.1 0.057 13.3 0.1 2.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf_ZIC PF18366.1 EGF99238.1 - 0.29 11.3 3.0 0.6 10.3 0.1 2.7 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 EGF99238.1 - 1.5 8.9 7.8 0.53 10.4 0.2 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger CrgA PF06781.12 EGF99239.1 - 0.11 12.5 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 Cell division protein CrgA BTB_2 PF02214.22 EGF99240.1 - 4.3e-05 23.8 0.1 0.00015 22.0 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain RCC1 PF00415.18 EGF99241.1 - 2.6e-63 210.4 14.0 2.7e-12 47.1 0.0 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGF99241.1 - 5.5e-30 102.5 37.2 8.3e-08 31.8 1.5 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Sugar_tr PF00083.24 EGF99243.1 - 2.1e-128 429.0 21.0 2.4e-128 428.8 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGF99243.1 - 8.6e-25 87.4 29.5 3.5e-13 49.2 10.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF99244.1 - 4.1e-127 424.8 19.9 4.7e-127 424.6 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGF99244.1 - 1.1e-24 87.0 27.8 4.1e-14 52.3 9.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Cation_efflux PF01545.21 EGF99244.1 - 0.098 12.4 11.7 1 9.1 1.1 3.4 2 1 1 3 3 3 0 Cation efflux family MFS_4 PF06779.14 EGF99244.1 - 0.16 11.2 16.2 0.057 12.7 3.8 2.6 2 1 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB RRM_1 PF00076.22 EGF99245.1 - 7.8e-46 153.8 1.4 8.3e-18 64.0 0.0 5.6 7 0 0 7 7 7 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF99245.1 - 4.9e-05 23.4 0.0 0.15 12.2 0.0 4.0 4 0 0 4 4 4 2 RNA recognition motif Flagellin_N PF00669.20 EGF99245.1 - 0.084 13.0 0.3 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Glyco_transf_22 PF03901.17 EGF99246.1 - 5.7e-86 289.4 17.7 2.3e-84 284.1 17.7 2.0 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family MSP PF01716.18 EGF99247.1 - 0.18 11.0 0.1 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide RNA_pol_3_Rpc31 PF11705.8 EGF99248.1 - 1 9.6 14.4 1.1 9.4 14.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 EGF99248.1 - 2.2 7.6 13.7 2.5 7.4 13.7 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EGF99248.1 - 5.9 4.9 17.6 6.4 4.7 17.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EGF99248.1 - 9.9 4.2 12.4 10 4.2 12.4 1.0 1 0 0 1 1 1 0 Nop14-like family RTC4 PF14474.6 EGF99249.1 - 4.2e-22 78.6 0.0 6.6e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain zf-CCHC PF00098.23 EGF99249.1 - 0.21 11.7 1.8 0.36 11.0 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Ccdc124 PF06244.12 EGF99250.1 - 9e-24 84.5 14.1 9e-24 84.5 14.1 2.0 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 PARM PF17061.5 EGF99250.1 - 0.4 10.8 7.8 0.53 10.4 7.8 1.1 1 0 0 1 1 1 0 PARM DUF4407 PF14362.6 EGF99250.1 - 2.3 7.5 9.8 0.47 9.8 6.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4554 PF15091.6 EGF99250.1 - 3.9 6.3 11.1 5.4 5.8 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) NUDIX PF00293.28 EGF99252.1 - 6.6e-11 42.4 0.3 8.6e-11 42.0 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain DUF4011 PF13195.6 EGF99252.1 - 0.067 13.1 0.2 0.1 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) CBP_BcsR PF10945.8 EGF99254.1 - 0.21 11.1 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR MyTH4 PF00784.17 EGF99257.1 - 0.023 15.2 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 MyTH4 domain LMP PF04778.12 EGF99262.1 - 0.025 14.5 1.7 0.033 14.1 1.7 1.1 1 0 0 1 1 1 0 LMP repeated region DUF1027 PF06265.11 EGF99262.1 - 0.057 13.4 0.1 0.075 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) Dor1 PF04124.12 EGF99263.1 - 1.5e-35 122.5 11.6 2.9e-30 105.1 8.8 3.3 2 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 EGF99263.1 - 0.00015 21.8 3.0 0.0038 17.3 0.5 3.4 3 0 0 3 3 3 1 Vps51/Vps67 AP_endonuc_2 PF01261.24 EGF99264.1 - 5.1e-17 62.0 0.0 6.4e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Peptidase_C54 PF03416.19 EGF99265.1 - 0.00034 20.1 0.0 0.00055 19.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 K_channel_TID PF07941.11 EGF99265.1 - 8.7 6.9 9.9 27 5.3 9.9 1.9 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain TRAM_LAG1_CLN8 PF03798.16 EGF99266.1 - 5.5e-36 124.2 22.3 5.5e-36 124.2 22.3 2.1 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EGF99266.1 - 1.9e-20 72.3 0.5 4.9e-20 70.9 0.5 1.8 1 0 0 1 1 1 1 TRAM1-like protein Ribosomal_S28e PF01200.18 EGF99267.1 - 6.6e-28 96.5 0.6 7.3e-28 96.4 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e adh_short PF00106.25 EGF99268.1 - 4.7e-17 62.1 0.0 7.1e-17 61.5 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGF99268.1 - 2.3e-08 33.9 0.0 3.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF99268.1 - 0.00039 20.4 0.2 0.084 12.8 0.0 2.2 2 0 0 2 2 2 2 KR domain gp32 PF08804.10 EGF99269.1 - 0.016 15.3 0.1 0.031 14.3 0.1 1.4 1 0 0 1 1 1 0 gp32 DNA binding protein like ATP11 PF06644.11 EGF99270.1 - 2.2e-76 257.3 7.7 2.8e-76 256.9 7.7 1.1 1 0 0 1 1 1 1 ATP11 protein MFS_1 PF07690.16 EGF99271.1 - 3e-36 125.1 29.3 1.5e-28 99.8 3.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF99271.1 - 1.7e-11 43.7 17.3 9.2e-11 41.3 17.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EGF99271.1 - 6.6e-05 22.4 0.5 6.6e-05 22.4 0.5 3.1 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB PSI_integrin PF17205.3 EGF99272.1 - 0.46 10.3 6.1 7.6 6.4 1.1 2.4 2 0 0 2 2 2 0 Integrin plexin domain PAS PF00989.25 EGF99273.1 - 0.00068 19.6 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 EGF99273.1 - 0.00071 19.7 10.1 0.00071 19.7 10.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EGF99274.1 - 5.9e-31 107.7 30.7 1e-30 106.9 30.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF99274.1 - 5.6e-11 42.0 21.0 1.2e-10 40.9 21.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EGF99274.1 - 0.022 13.2 2.0 0.046 12.1 2.0 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector SET PF00856.28 EGF99275.1 - 2.5e-07 31.2 0.0 4.4e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 SET domain SET PF00856.28 EGF99276.1 - 5.1e-09 36.7 0.0 9.6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 SET domain RdRP PF05183.12 EGF99278.1 - 9.4e-53 179.8 0.0 3.5e-31 108.5 0.0 3.0 1 1 1 2 2 2 2 RNA dependent RNA polymerase SET PF00856.28 EGF99279.1 - 5.9e-08 33.3 0.0 1.4e-07 32.1 0.0 1.8 1 1 0 1 1 1 1 SET domain Glyco_transf_90 PF05686.12 EGF99281.1 - 7.3e-05 21.8 0.0 0.00019 20.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 PseudoU_synth_1 PF01416.20 EGF99282.1 - 1.8e-09 38.1 0.0 1.1e-08 35.5 0.0 2.2 2 0 0 2 2 2 1 tRNA pseudouridine synthase CDC45 PF02724.14 EGF99282.1 - 1 7.6 4.3 1.6 6.9 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 EGF99282.1 - 2.5 7.3 4.6 4.7 6.3 4.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGF99282.1 - 3 6.5 4.9 5.1 5.7 4.9 1.2 1 0 0 1 1 1 0 Presenilin ECH_1 PF00378.20 EGF99283.1 - 4.1e-30 104.9 0.0 7.2e-30 104.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGF99283.1 - 2.9e-19 69.7 0.0 1.5e-17 64.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Homez PF11569.8 EGF99283.1 - 0.11 11.9 0.1 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Med12 PF09497.10 EGF99284.1 - 1.4e-27 95.8 0.7 3.1e-27 94.7 0.2 2.0 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 EGF99284.1 - 0.0018 17.2 2.5 0.0034 16.3 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain PBP1_TM PF14812.6 EGF99284.1 - 3.6 8.0 7.0 9 6.7 7.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PLA2_B PF01735.18 EGF99285.1 - 2.2e-91 306.8 3.7 1.4e-83 281.0 0.2 3.0 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.22 EGF99285.1 - 0.055 13.6 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 Patatin-like phospholipase NPV_P10 PF05531.12 EGF99286.1 - 0.062 13.8 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CxC5 PF18718.1 EGF99288.1 - 3.8e-07 30.2 0.8 1.9e-05 24.7 0.1 2.6 2 0 0 2 2 2 2 CxC5 like cysteine cluster associated with KDZ transposases Glyco_hydro_47 PF01532.20 EGF99291.1 - 2.6e-99 333.2 0.0 3.4e-99 332.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Oxysterol_BP PF01237.18 EGF99292.1 - 5.8e-134 446.6 0.2 1.7e-133 445.1 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 EGF99292.1 - 1.4e-12 48.0 0.1 7.2e-10 39.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGF99292.1 - 4.6e-10 38.8 0.0 0.0024 18.2 0.0 4.0 4 0 0 4 4 3 3 Ankyrin repeat Ank_5 PF13857.6 EGF99292.1 - 9.2e-10 38.6 0.7 7.1e-05 23.0 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGF99292.1 - 1.5e-09 37.8 1.8 0.0051 17.2 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.29 EGF99292.1 - 1e-07 32.4 0.0 2.7e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 EGF99292.1 - 3.8e-07 30.5 0.4 0.0039 17.7 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PH_8 PF15409.6 EGF99292.1 - 0.00016 21.9 0.3 0.0006 20.0 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EGF99292.1 - 0.0015 18.9 0.2 0.01 16.2 0.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain DnaG_DnaB_bind PF08278.11 EGF99292.1 - 0.013 16.1 0.2 0.013 16.1 0.2 2.4 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding KxDL PF10241.9 EGF99292.1 - 2.2 8.6 6.1 18 5.7 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein SET PF00856.28 EGF99294.1 - 2e-06 28.3 0.0 6.8e-06 26.6 0.0 2.0 2 1 0 2 2 2 1 SET domain SET PF00856.28 EGF99295.1 - 8.1e-09 36.1 0.0 2.2e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 SET domain MFS_1 PF07690.16 EGF99296.1 - 4.2e-26 91.7 23.2 4.2e-26 91.7 23.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EGF99296.1 - 3.5e-05 23.3 2.1 3.5e-05 23.3 2.1 2.0 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 EGF99296.1 - 0.00047 19.2 22.5 0.0031 16.4 22.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGF99297.1 - 6.4e-37 127.3 48.4 6.7e-36 123.9 24.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF99297.1 - 4.4e-11 42.3 3.8 4.4e-11 42.3 3.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EGF99297.1 - 3.6e-07 29.8 0.9 3.6e-07 29.8 0.9 3.0 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 EGF99297.1 - 0.12 10.8 9.7 0.01 14.3 1.7 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_1 PF07690.16 EGF99298.1 - 1.4e-18 67.0 22.5 1.4e-18 67.0 22.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF99298.1 - 4.1e-05 22.6 4.8 4.1e-05 22.6 4.8 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EGF99299.1 - 1.7e-23 83.2 13.5 1.7e-23 83.2 13.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF99299.1 - 4.6e-09 35.7 6.7 7.1e-09 35.0 6.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EGF99299.1 - 1.4e-05 23.7 1.2 2.4e-05 23.0 1.2 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_4 PF06779.14 EGF99299.1 - 0.07 12.4 9.9 0.4 9.9 6.9 2.7 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB PRA1 PF03208.19 EGF99300.1 - 4.4e-35 120.4 0.1 5.2e-35 120.2 0.1 1.0 1 0 0 1 1 1 1 PRA1 family protein DIT1_PvcA PF05141.12 EGF99301.1 - 0.049 13.1 1.9 0.066 12.7 1.9 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF1644 PF07800.12 EGF99301.1 - 0.97 9.5 4.3 0.29 11.2 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-C2H2 PF00096.26 EGF99303.1 - 1.4e-12 47.3 5.4 1.3e-06 28.5 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGF99303.1 - 1.4e-08 34.7 6.1 1.5e-06 28.4 0.3 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF99303.1 - 6.4e-08 32.8 4.4 0.0034 18.1 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGF99303.1 - 2.6e-07 30.7 0.2 0.0085 16.4 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGF99303.1 - 2e-06 28.0 0.9 0.0054 17.1 0.6 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGF99303.1 - 0.00011 22.1 4.1 0.074 13.1 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EGF99303.1 - 0.0011 18.8 3.0 0.039 13.9 0.3 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-Di19 PF05605.12 EGF99303.1 - 0.0071 16.6 1.1 0.014 15.7 1.1 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Endonuclease_7 PF02945.15 EGF99303.1 - 0.032 14.2 2.8 1.6 8.7 2.8 2.2 1 1 1 2 2 2 0 Recombination endonuclease VII GAGA PF09237.11 EGF99303.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 GAGA factor DpnI PF06044.12 EGF99303.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Dam-replacing family zf-C2H2_9 PF16293.5 EGF99303.1 - 0.098 12.5 0.2 8.8 6.3 0.0 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn_ribbon_SprT PF17283.2 EGF99303.1 - 0.13 12.2 0.8 0.27 11.2 0.8 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-MYST PF17772.1 EGF99303.1 - 0.15 11.7 0.2 0.8 9.4 0.1 2.4 1 1 1 2 2 2 0 MYST family zinc finger domain zf_UBZ PF18439.1 EGF99303.1 - 0.15 11.7 0.6 10 5.8 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger FdhE PF04216.12 EGF99303.1 - 0.27 11.1 0.4 0.35 10.7 0.4 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-C2HE PF16278.5 EGF99303.1 - 0.3 11.6 2.1 0.96 9.9 2.2 1.7 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_9 PF14369.6 EGF99303.1 - 0.44 10.8 2.2 2.8 8.3 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon zf-BED PF02892.15 EGF99303.1 - 2.1 8.5 4.9 8.7 6.5 4.9 2.0 1 1 0 1 1 1 0 BED zinc finger Clat_adaptor_s PF01217.20 EGF99304.1 - 1.6e-48 164.3 0.9 1.9e-48 164.0 0.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF5372 PF17342.2 EGF99305.1 - 0.25 11.8 0.8 2.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5372) Pro_isomerase PF00160.21 EGF99307.1 - 1.7e-46 158.4 0.1 2.2e-46 158.0 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NAP PF00956.18 EGF99308.1 - 3e-90 302.1 1.0 4.2e-90 301.6 1.0 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.12 EGF99308.1 - 0.53 10.0 16.7 0.21 11.3 8.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 EGF99308.1 - 7.8 4.4 7.2 0.24 9.5 0.4 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF3195 PF11424.8 EGF99310.1 - 0.1 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGF99310.1 - 0.15 11.0 0.4 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 NUC194 domain DUF2170 PF09938.9 EGF99310.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) DUF3195 PF11424.8 EGF99323.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGF99323.1 - 0.16 10.9 0.4 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 NUC194 domain DUF2170 PF09938.9 EGF99323.1 - 0.21 11.3 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) UPF0242 PF06785.11 EGF99330.1 - 0.27 11.3 1.3 0.44 10.6 1.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5358 PF17311.2 EGF99330.1 - 0.36 10.8 3.6 0.32 11.0 2.3 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5358) HSP70 PF00012.20 EGF99330.1 - 0.49 8.5 9.6 0.61 8.2 9.6 1.1 1 0 0 1 1 1 0 Hsp70 protein TraV PF09676.10 EGF99330.1 - 4 8.4 7.4 2.6 9.0 5.2 1.7 1 1 1 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Mannosyl_trans3 PF11051.8 EGF99333.1 - 1.9e-19 70.1 0.1 6.3e-06 25.7 0.0 3.2 2 1 0 3 3 3 3 Mannosyltransferase putative rRNA_processing PF08524.11 EGF99335.1 - 3e-05 24.1 18.0 0.0097 15.9 3.4 2.4 2 1 0 2 2 2 2 rRNA processing PALP PF00291.25 EGF99336.1 - 0.091 12.2 0.0 0.091 12.2 0.0 1.0 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Cation_efflux PF01545.21 EGF99340.1 - 4.2e-14 52.8 3.8 4.7e-14 52.6 3.8 1.0 1 0 0 1 1 1 1 Cation efflux family Peptidase_M20 PF01546.28 EGF99342.1 - 1.7e-24 86.7 0.0 2.9e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EGF99342.1 - 1.6e-15 57.2 14.8 8.9e-05 23.2 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat M20_dimer PF07687.14 EGF99342.1 - 1.6e-09 37.6 0.0 2.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 EGF99342.1 - 0.0047 17.2 0.2 23 5.3 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGF99342.1 - 0.015 14.0 0.8 0.83 8.2 0.0 2.8 3 1 1 4 4 4 0 Nucleoporin Nup120/160 OPT PF03169.15 EGF99343.1 - 3.2e-131 439.0 50.4 7.7e-131 437.7 50.4 1.5 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DUF4173 PF13777.6 EGF99343.1 - 0.66 9.4 7.6 2.9 7.3 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) BPL_LplA_LipB PF03099.19 EGF99344.1 - 8.8e-05 22.4 0.0 0.0015 18.4 0.0 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 EGF99344.1 - 0.001 19.0 0.2 0.0038 17.2 0.2 2.0 1 1 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus Corona_RPol_N PF06478.13 EGF99347.1 - 0.13 11.2 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 Coronavirus RPol N-terminus DUF2457 PF10446.9 EGF99348.1 - 0.03 13.5 9.4 0.065 12.4 9.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 EGF99348.1 - 0.26 10.6 6.9 0.52 9.6 6.9 1.4 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 EGF99348.1 - 0.35 9.4 3.3 0.56 8.7 3.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.6 EGF99348.1 - 0.35 11.2 11.8 0.91 9.9 11.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_pol_3_Rpc31 PF11705.8 EGF99348.1 - 0.63 10.2 12.2 0.27 11.5 9.3 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Pes-10 PF07149.11 EGF99348.1 - 1.5 7.8 7.1 2.7 7.0 7.1 1.3 1 0 0 1 1 1 0 Pes-10 Pox_Ag35 PF03286.14 EGF99348.1 - 4.5 7.0 12.5 2.8 7.7 8.8 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 EGF99348.1 - 6.2 4.8 8.8 10 4.0 8.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 EGF99348.1 - 6.9 6.7 12.4 1.5 8.8 8.4 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal ANAPC15 PF15243.6 EGF99348.1 - 8.1 6.9 17.4 21 5.6 11.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 ORC6 PF05460.13 EGF99348.1 - 9.2 5.4 12.7 0.068 12.4 2.5 2.4 3 0 0 3 3 3 0 Origin recognition complex subunit 6 (ORC6) CxC1 PF18802.1 EGF99350.1 - 1.7e-22 79.5 0.1 3.7e-22 78.4 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF99350.1 - 3.8e-08 33.4 0.1 9.5e-08 32.2 0.1 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGF99350.1 - 0.015 15.1 0.0 0.041 13.7 0.0 1.7 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases Nudix_N PF12535.8 EGF99350.1 - 0.043 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal HD-ZIP_N PF04618.12 EGF99350.1 - 0.16 12.5 1.2 31 5.1 0.1 2.9 2 1 0 2 2 2 0 HD-ZIP protein N terminus MCPVI PF02993.14 EGF99353.1 - 1.3 8.8 5.8 1.8 8.3 5.8 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Pre-PUA PF17832.1 EGF99354.1 - 1.8e-20 73.4 0.7 3.8e-20 72.4 0.7 1.6 1 1 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EGF99354.1 - 9e-18 64.0 0.0 1.3e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 PUA domain CTP_transf_like PF01467.26 EGF99356.1 - 2.5e-13 50.5 0.0 3e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like ATP-sulfurylase PF01747.17 EGF99356.1 - 0.084 12.3 0.0 0.93 8.9 0.0 2.0 2 0 0 2 2 2 0 ATP-sulfurylase FAD_syn PF06574.12 EGF99356.1 - 0.15 12.0 2.2 0.12 12.3 0.6 1.7 2 1 0 2 2 2 0 FAD synthetase RPA_interact_M PF14767.6 EGF99361.1 - 0.092 13.3 5.9 0.15 12.7 5.9 1.3 1 0 0 1 1 1 0 Replication protein A interacting middle DUF4175 PF13779.6 EGF99361.1 - 1.5 6.6 5.6 2.3 6.0 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PP2C_C PF07830.13 EGF99361.1 - 4.4 7.8 0.0 4.4 7.8 0.0 2.8 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Prefoldin_2 PF01920.20 EGF99362.1 - 0.04 13.9 5.2 0.049 13.6 0.9 2.9 2 1 1 3 3 3 0 Prefoldin subunit DUF4201 PF13870.6 EGF99362.1 - 0.047 13.4 0.8 0.047 13.4 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) SlyX PF04102.12 EGF99362.1 - 0.11 13.2 4.6 0.53 10.9 4.6 2.2 1 0 0 1 1 1 0 SlyX XhlA PF10779.9 EGF99362.1 - 0.42 10.8 2.8 0.84 9.9 1.6 2.1 2 1 0 2 2 2 0 Haemolysin XhlA MGC-24 PF05283.11 EGF99363.1 - 0.33 11.4 3.3 0.49 10.8 3.3 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SNF2_N PF00176.23 EGF99365.1 - 1.5e-49 168.6 4.0 1.6e-28 99.4 0.5 2.0 1 1 1 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 EGF99365.1 - 0.00018 21.6 0.1 0.14 12.2 0.0 2.1 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGF99365.1 - 0.016 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DEAD PF00270.29 EGF99365.1 - 0.022 14.5 0.1 5.1 6.8 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.6 EGF99365.1 - 0.14 12.4 0.2 0.34 11.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain Helicase_C PF00271.31 EGF99366.1 - 4.8e-07 30.1 0.0 6.6e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain FAR1 PF03101.15 EGF99367.1 - 0.0017 19.0 0.0 0.0079 16.9 0.0 2.0 2 0 0 2 2 2 1 FAR1 DNA-binding domain Peptidase_C65 PF10275.9 EGF99367.1 - 0.0084 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain DUF1730 PF08331.10 EGF99368.1 - 0.0018 18.1 0.1 0.37 10.7 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1730) BUD22 PF09073.10 EGF99368.1 - 0.31 10.3 10.8 0.54 9.6 10.8 1.3 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 EGF99368.1 - 4.9 7.0 22.1 0.95 9.4 18.3 1.7 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF498 PF04430.14 EGF99370.1 - 2.4e-17 63.0 0.0 3.3e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) EloA-BP1 PF15870.5 EGF99371.1 - 8.3e-05 22.9 0.4 0.0026 18.0 0.1 2.3 2 0 0 2 2 2 2 ElonginA binding-protein 1 YebO PF13974.6 EGF99372.1 - 0.18 11.9 0.8 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 YebO-like protein Arabino_trans_C PF14896.6 EGF99374.1 - 0.89 8.5 6.8 0.26 10.3 2.9 1.9 2 0 0 2 2 2 0 EmbC C-terminal domain DNA_pol_A_exo1 PF01612.20 EGF99375.1 - 2.1e-15 56.9 0.4 3e-15 56.4 0.4 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HATPase_c_5 PF14501.6 EGF99375.1 - 0.051 13.5 0.1 0.091 12.7 0.1 1.3 1 0 0 1 1 1 0 GHKL domain ADK PF00406.22 EGF99377.1 - 5.2e-14 52.6 0.0 5.8e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 EGF99377.1 - 9.2e-13 47.9 0.0 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 EGF99377.1 - 0.006 17.0 0.0 0.008 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.11 EGF99380.1 - 0.38 9.6 6.2 0.81 8.5 6.2 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Uds1 PF15456.6 EGF99380.1 - 0.44 10.7 5.0 1.6 8.9 0.1 2.4 2 1 0 2 2 2 0 Up-regulated During Septation Alpha-amylase PF00128.24 EGF99381.1 - 0.21 11.1 1.1 0.37 10.3 1.1 1.3 1 0 0 1 1 1 0 Alpha amylase, catalytic domain DUF1075 PF06388.11 EGF99381.1 - 3.9 7.6 5.9 1 9.4 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1075) YfhO PF09586.10 EGF99386.1 - 0.34 9.1 7.9 0.46 8.7 7.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RsgA_GTPase PF03193.16 EGF99387.1 - 0.073 13.0 0.0 4.1 7.3 0.0 2.1 1 1 1 2 2 2 0 RsgA GTPase DEAD PF00270.29 EGF99387.1 - 0.089 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase Selenoprotein_S PF06936.11 EGF99388.1 - 0.46 10.3 9.9 0.65 9.8 9.9 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) RPAP3_C PF13877.6 EGF99390.1 - 2.8e-12 47.0 0.0 5.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 EGF99390.1 - 6.3e-07 29.0 0.2 0.00021 21.2 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGF99390.1 - 3.9e-06 26.4 0.0 0.00092 18.9 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGF99390.1 - 0.007 16.5 0.1 0.053 13.7 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF99390.1 - 0.15 12.4 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat ERCC4 PF02732.15 EGF99391.1 - 6.1e-18 65.5 0.3 1.1e-17 64.7 0.3 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 EGF99391.1 - 0.014 15.7 0.3 0.031 14.6 0.3 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain SelP_N PF04592.14 EGF99391.1 - 0.068 12.6 0.2 0.13 11.6 0.2 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region IL11 PF07400.11 EGF99394.1 - 0.044 13.4 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Interleukin 11 Retrotran_gag_2 PF14223.6 EGF99396.1 - 2.2e-07 30.6 0.0 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.6 EGF99396.1 - 0.00035 20.3 0.0 0.0007 19.4 0.0 1.5 1 0 0 1 1 1 1 Zinc knuckle RXT2_N PF08595.11 EGF99398.1 - 3.3 7.7 12.7 8.3 6.4 1.2 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4820 PF16091.5 EGF99398.1 - 8.1 5.7 12.1 0.63 9.4 4.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) KDZ PF18758.1 EGF99400.1 - 2.7e-27 95.8 0.0 3.6e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGF99400.1 - 1.5e-06 28.3 0.0 3.1e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF99400.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases Ribonuc_P_40 PF08584.11 EGF99402.1 - 0.16 11.3 6.1 0.027 13.7 1.0 2.2 2 0 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit BP28CT PF08146.12 EGF99404.1 - 7e-36 123.4 2.1 1.1e-35 122.8 0.4 2.4 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EGF99404.1 - 3.1e-15 56.5 0.9 3.1e-15 56.5 0.9 5.4 5 2 1 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 EGF99404.1 - 0.00051 20.1 0.6 0.014 15.6 0.1 4.0 3 0 0 3 3 3 1 HEAT repeat ParcG PF10274.9 EGF99404.1 - 0.013 15.6 4.7 21 5.1 0.0 5.4 5 1 0 5 5 5 0 Parkin co-regulated protein Pan3_PK PF18101.1 EGF99407.1 - 2.7e-59 199.1 0.1 4.3e-59 198.4 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EGF99407.1 - 0.00032 20.2 0.0 0.012 15.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF99407.1 - 0.048 12.9 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Polysacc_deac_1 PF01522.21 EGF99408.1 - 1e-26 93.3 0.0 2.7e-26 91.9 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGF99408.1 - 4e-05 23.0 0.0 8.8e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 UPF0180 PF03698.13 EGF99408.1 - 0.18 12.0 0.0 10 6.3 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) ABC1 PF03109.16 EGF99410.1 - 1.5e-27 96.2 0.0 2.7e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EGF99410.1 - 8.4e-06 25.3 0.3 0.0029 17.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 EGF99410.1 - 0.0013 18.7 0.0 0.0029 17.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGF99410.1 - 0.011 14.6 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EGF99410.1 - 0.041 13.5 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family RRM_1 PF00076.22 EGF99412.1 - 2.3e-20 72.2 0.0 2.8e-10 39.9 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGF99412.1 - 1.9e-07 30.7 0.0 0.0055 16.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF99412.1 - 0.0039 17.0 0.0 4 7.4 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif APH PF01636.23 EGF99414.1 - 3e-35 122.3 0.0 3.8e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGF99414.1 - 2.1e-08 34.0 0.0 2.8e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 EGF99414.1 - 1.3e-05 24.6 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 EGF99414.1 - 0.032 13.6 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.11 EGF99414.1 - 0.11 11.4 0.2 1.2 7.9 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1679) Sec23_trunk PF04811.15 EGF99415.1 - 0.11 12.1 0.0 2.5 7.6 0.0 2.3 1 1 1 2 2 2 0 Sec23/Sec24 trunk domain LRR_4 PF12799.7 EGF99416.1 - 0.00041 20.7 9.8 6.6 7.3 0.0 6.3 3 2 2 6 6 6 4 Leucine Rich repeats (2 copies) YtxH PF12732.7 EGF99417.1 - 0.2 12.2 0.3 0.45 11.1 0.3 1.5 1 0 0 1 1 1 0 YtxH-like protein LMBR1 PF04791.16 EGF99417.1 - 0.54 9.1 1.1 0.61 8.9 1.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Myotub-related PF06602.14 EGF99418.1 - 9e-139 462.3 1.1 1.2e-138 461.9 1.1 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 EGF99418.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGF99418.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family GCP_C_terminal PF04130.13 EGF99420.1 - 1.2e-78 264.8 0.2 1.6e-78 264.3 0.2 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGF99420.1 - 5.3e-62 210.2 0.7 2.1e-61 208.2 0.3 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal BTB PF00651.31 EGF99421.1 - 8.8e-08 32.4 0.0 8e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain CUE PF02845.16 EGF99422.1 - 1.1e-06 28.3 0.1 1.8e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 CUE domain zf-C2H2 PF00096.26 EGF99424.1 - 4.6e-06 26.8 1.8 1.6e-05 25.1 1.8 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EGF99424.1 - 0.0025 17.5 0.3 0.0051 16.5 0.3 1.6 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 EGF99424.1 - 0.004 17.9 1.4 0.013 16.3 1.4 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGF99424.1 - 0.056 13.7 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGF99424.1 - 0.058 13.8 0.2 0.12 12.8 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EGF99424.1 - 0.33 11.5 3.6 4.1 8.0 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double domain MMPL PF03176.15 EGF99426.1 - 0.073 12.0 1.6 0.086 11.8 1.6 1.1 1 0 0 1 1 1 0 MMPL family DUF900 PF05990.12 EGF99427.1 - 0.032 13.8 1.1 2.3 7.7 0.2 2.2 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Membr_traf_MHD PF10540.9 EGF99428.1 - 3.1e-22 79.3 4.7 4.6e-13 49.6 0.0 3.9 3 1 1 4 4 4 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EGF99428.1 - 2.1e-10 40.8 0.0 4.6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain SPATA1_C PF15743.5 EGF99428.1 - 0.067 13.3 1.7 0.17 12.0 0.4 2.4 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus PMSR PF01625.21 EGF99429.1 - 1.4e-58 197.4 5.3 1.6e-58 197.2 5.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase HHH_8 PF14716.6 EGF99429.1 - 0.1 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain EcKinase PF02958.20 EGF99430.1 - 0.17 11.2 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase C2 PF00168.30 EGF99433.1 - 2.4e-06 27.8 0.0 0.018 15.3 0.0 2.5 2 0 0 2 2 2 2 C2 domain CxC1 PF18802.1 EGF99434.1 - 6.8e-21 74.4 0.5 1.4e-20 73.3 0.5 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF99434.1 - 4.5e-06 26.8 0.2 8.7e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases UME PF08064.13 EGF99436.1 - 7.1e-21 74.0 0.1 1.8e-19 69.6 0.0 2.9 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.23 EGF99436.1 - 6.9e-08 32.1 0.1 1.3e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 EGF99436.1 - 0.038 13.9 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Aldo_ket_red PF00248.21 EGF99440.1 - 7.4e-43 146.8 0.0 8.6e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_92 PF07971.12 EGF99442.1 - 2.9e-48 164.9 2.7 3.9e-48 164.5 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 RRM_1 PF00076.22 EGF99443.1 - 0.0056 16.5 0.2 0.39 10.6 0.2 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3887 PF13026.6 EGF99443.1 - 0.059 14.2 0.1 0.091 13.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3887) FerA PF08165.11 EGF99443.1 - 0.11 12.4 0.1 5.9 6.9 0.1 2.3 2 1 0 2 2 2 0 FerA (NUC095) domain FTO_NTD PF12933.7 EGF99447.1 - 0.0095 15.2 0.4 0.012 14.9 0.4 1.1 1 0 0 1 1 1 1 FTO catalytic domain Mem_trans PF03547.18 EGF99447.1 - 0.12 10.8 0.9 0.14 10.5 0.9 1.1 1 0 0 1 1 1 0 Membrane transport protein zf-CCHC PF00098.23 EGF99448.1 - 7.4e-05 22.6 3.7 0.00011 22.1 3.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGF99448.1 - 0.099 12.4 1.5 0.16 11.8 1.5 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 EGF99448.1 - 0.48 10.3 3.1 1.1 9.1 3.1 1.6 1 0 0 1 1 1 0 Zinc knuckle ThiF PF00899.21 EGF99449.1 - 4.5e-62 209.6 0.0 6.3e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EGF99449.1 - 3.5e-21 75.1 0.7 6.2e-21 74.3 0.7 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EGF99449.1 - 0.016 15.3 0.1 0.068 13.2 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EGF99449.1 - 0.018 15.6 0.0 0.035 14.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.8 EGF99449.1 - 0.12 12.5 1.1 0.26 11.5 1.1 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein UDPG_MGDP_dh_N PF03721.14 EGF99449.1 - 0.19 11.3 0.1 0.35 10.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_N PF08240.12 EGF99450.1 - 2e-20 72.7 2.6 3.6e-20 71.9 2.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGF99450.1 - 8.8e-12 45.1 0.0 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGF99450.1 - 0.00067 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EGF99450.1 - 0.02 14.3 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.6 EGF99450.1 - 0.025 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ELFV_dehydrog PF00208.21 EGF99450.1 - 0.092 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase LEA_5 PF00477.17 EGF99451.1 - 0.1 13.1 8.4 0.11 12.9 6.3 1.9 1 1 1 2 2 2 0 Small hydrophilic plant seed protein CLASP_N PF12348.8 EGF99452.1 - 1.8e-67 227.2 0.3 4.5e-58 196.5 0.0 3.5 2 1 1 3 3 3 3 CLASP N terminal HEAT PF02985.22 EGF99452.1 - 6e-07 29.2 0.3 0.2 12.0 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 EGF99452.1 - 0.00098 19.5 0.7 12 6.4 0.0 5.2 4 1 1 5 5 5 1 HEAT repeats Cnd1 PF12717.7 EGF99452.1 - 0.0026 17.8 0.5 8.1 6.5 0.0 4.6 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGF99452.1 - 0.012 16.1 3.7 2 9.0 0.0 4.1 4 1 1 5 5 5 0 HEAT-like repeat MMS19_C PF12460.8 EGF99452.1 - 0.022 13.9 3.0 0.042 12.9 1.5 2.2 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Cohesin_HEAT PF12765.7 EGF99452.1 - 0.03 14.6 2.8 2.7 8.4 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion IFRD PF05004.13 EGF99452.1 - 0.032 13.4 0.9 0.73 8.9 0.1 2.9 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) CMAS PF02353.20 EGF99453.1 - 1.3e-63 214.9 0.0 1.6e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGF99453.1 - 8.4e-09 36.0 0.0 2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF99453.1 - 2.1e-08 34.7 0.0 6.5e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF99453.1 - 3.6e-08 33.4 0.0 7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF99453.1 - 0.00017 22.3 0.0 0.0003 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EGF99453.1 - 0.00029 20.4 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 EGF99453.1 - 0.0019 17.8 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGF99453.1 - 0.003 17.4 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Proteasome PF00227.26 EGF99454.1 - 4.6e-52 176.3 0.0 5.8e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGF99454.1 - 7.3e-14 51.1 0.0 1.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SNF5 PF04855.12 EGF99455.1 - 2.4e-65 220.7 1.9 7.9e-65 219.0 1.9 1.8 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 nsp9 PF08710.10 EGF99455.1 - 0.17 12.3 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 nsp9 replicase Tyrosinase PF00264.20 EGF99458.1 - 4.8e-32 112.1 0.2 7.6e-32 111.4 0.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase SNCAIP_SNCA_bd PF16700.5 EGF99458.1 - 0.18 11.6 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain Tyrosinase PF00264.20 EGF99459.1 - 3.7e-27 96.1 0.0 6.5e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase S4 PF01479.25 EGF99460.1 - 2.3e-09 36.8 0.0 4.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain NIF PF03031.18 EGF99461.1 - 0.022 14.6 0.0 0.39 10.5 0.0 2.3 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase EFP_N PF08207.12 EGF99462.1 - 0.055 13.5 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Snf7 PF03357.21 EGF99463.1 - 5e-41 140.2 17.9 5e-41 140.2 17.9 2.0 1 1 1 2 2 2 1 Snf7 hNIFK_binding PF12196.8 EGF99463.1 - 0.025 14.0 0.8 0.059 12.9 0.1 2.0 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Ribosomal_60s PF00428.19 EGF99463.1 - 0.066 13.8 4.1 1 10.0 0.8 2.6 2 1 0 2 2 2 0 60s Acidic ribosomal protein DUF4200 PF13863.6 EGF99463.1 - 0.26 11.7 23.3 0.19 12.1 3.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.9 EGF99463.1 - 0.66 9.0 12.7 0.42 9.7 11.2 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_L13 PF00572.18 EGF99464.1 - 5.8e-05 23.3 0.1 0.00012 22.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 GTP_EFTU PF00009.27 EGF99465.1 - 2.2e-54 184.0 0.0 3.4e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGF99465.1 - 2.5e-41 140.5 0.0 6e-41 139.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGF99465.1 - 2.2e-15 56.8 1.1 2.2e-15 56.8 1.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGF99465.1 - 0.0022 18.0 0.1 0.049 13.7 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EGF99465.1 - 0.015 15.1 0.4 0.015 15.1 0.4 2.0 3 0 0 3 3 3 0 Elongation factor Tu domain 4 FlpD PF02662.16 EGF99465.1 - 0.033 14.2 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit Peptidase_M16_C PF05193.21 EGF99466.1 - 1.8e-20 73.7 0.0 7.6e-13 48.9 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGF99466.1 - 1.3e-06 28.5 0.1 4.6e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PHD PF00628.29 EGF99467.1 - 8e-11 41.7 6.7 1.1e-10 41.3 5.3 2.0 2 0 0 2 2 2 1 PHD-finger zf-CpG_bind_C PF12269.8 EGF99467.1 - 0.00036 20.4 1.5 0.00036 20.4 1.5 2.7 3 0 0 3 3 3 1 CpG binding protein zinc finger C terminal domain PHD_2 PF13831.6 EGF99467.1 - 0.038 13.5 2.3 0.096 12.3 2.3 1.7 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.6 EGF99467.1 - 0.064 13.7 0.7 0.37 11.2 0.2 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Zf_RING PF16744.5 EGF99467.1 - 0.64 10.2 6.0 0.23 11.6 2.6 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger Kinesin PF00225.23 EGF99468.1 - 8.2e-101 337.3 1.1 9.7e-101 337.0 1.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF99468.1 - 2.6e-29 102.1 0.2 5.2e-29 101.1 0.2 1.5 1 0 0 1 1 1 1 Microtubule binding ATPase_2 PF01637.18 EGF99468.1 - 0.097 12.6 0.1 0.36 10.7 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EGF99468.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MoaE PF02391.17 EGF99471.1 - 5.9e-21 74.9 0.0 6.7e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 MoaE protein Peptidase_M16_C PF05193.21 EGF99472.1 - 5.8e-21 75.3 0.0 1.1e-13 51.7 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGF99472.1 - 1.1e-06 28.7 0.1 3.3e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Tim17 PF02466.19 EGF99473.1 - 2.5e-07 31.0 9.3 6e-07 29.8 8.6 2.0 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Aldo_ket_red PF00248.21 EGF99474.1 - 1.3e-65 221.5 0.0 1.6e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DeoC PF01791.9 EGF99475.1 - 3.8e-11 43.1 0.2 4.9e-11 42.7 0.2 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DAHP_snth_FXD PF18152.1 EGF99475.1 - 0.0043 16.8 0.4 0.097 12.5 0.0 3.1 3 1 1 4 4 4 1 DAHP synthase ferredoxin-like domain DHO_dh PF01180.21 EGF99475.1 - 0.0073 15.6 1.3 0.017 14.3 0.5 1.9 2 1 0 2 2 2 1 Dihydroorotate dehydrogenase FtsX_ECD PF18075.1 EGF99475.1 - 0.075 13.7 0.6 0.7 10.6 0.1 2.3 2 0 0 2 2 2 0 FtsX extracellular domain UPF0225 PF17775.1 EGF99475.1 - 0.14 13.0 0.0 0.27 12.0 0.0 1.4 1 0 0 1 1 1 0 UPF0225 domain Kinesin PF00225.23 EGF99476.1 - 6.9e-86 288.2 0.2 9.2e-86 287.8 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF99476.1 - 5.1e-18 65.4 0.0 9.3e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding DUF4200 PF13863.6 EGF99476.1 - 0.0044 17.4 1.9 0.0069 16.8 0.2 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) DUF724 PF05266.14 EGF99476.1 - 0.13 12.1 1.9 1.7 8.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) MCPVI PF02993.14 EGF99477.1 - 0.018 14.9 1.0 0.018 14.9 1.0 2.1 2 1 0 2 2 2 0 Minor capsid protein VI PMSI1 PF15322.6 EGF99477.1 - 0.029 13.8 4.0 0.51 9.7 2.3 2.3 2 0 0 2 2 2 0 Protein missing in infertile sperm 1, putative Peroxidase_2 PF01328.17 EGF99479.1 - 8.7e-27 94.9 0.0 6e-26 92.1 0.0 2.0 1 1 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 EGF99480.1 - 1.5e-26 94.1 0.0 2.1e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 DUF5107 PF17128.4 EGF99480.1 - 0.0059 15.8 0.0 0.0086 15.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5107) Peroxidase_2 PF01328.17 EGF99482.1 - 4.2e-32 112.2 0.0 4.9e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 PAP1 PF08601.10 EGF99483.1 - 0.22 11.2 4.3 0.27 10.9 4.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Ribosomal_L13e PF01294.18 EGF99484.1 - 1.3e-73 246.7 4.8 1.9e-73 246.1 4.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e UEV PF05743.13 EGF99485.1 - 4.3e-36 123.4 0.0 7e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EGF99485.1 - 2.7e-27 94.5 0.5 4.5e-27 93.8 0.5 1.4 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 EGF99485.1 - 0.034 13.8 0.2 0.078 12.6 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme zf-C2H2_2 PF12756.7 EGF99486.1 - 0.15 12.4 0.1 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.25 EGF99487.1 - 1.6e-32 112.9 0.0 2.2e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF99487.1 - 3.5e-18 65.8 0.0 4.6e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF99487.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like DUF5082 PF16888.5 EGF99489.1 - 0.042 14.1 0.5 0.1 12.9 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Baculo_PEP_C PF04513.12 EGF99489.1 - 0.059 13.4 0.2 0.15 12.1 0.2 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FCH PF00611.23 EGF99490.1 - 4.6e-12 46.0 4.1 2.9e-11 43.5 0.2 2.8 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DHC_N1 PF08385.12 EGF99490.1 - 0.0017 17.1 1.0 0.0034 16.1 1.0 1.4 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 CDP-OH_P_transf PF01066.21 EGF99491.1 - 1.8e-17 63.9 0.1 1.8e-17 63.9 0.1 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Mito_carr PF00153.27 EGF99492.1 - 1.9e-67 223.2 5.7 7.4e-24 83.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Retrotran_gag_2 PF14223.6 EGF99495.1 - 1.1e-05 25.2 0.4 1.8e-05 24.4 0.4 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type 3-dmu-9_3-mt PF06983.13 EGF99496.1 - 0.005 17.4 0.1 0.0054 17.2 0.1 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase BRCT PF00533.26 EGF99497.1 - 0.00024 21.4 0.2 0.0017 18.7 0.2 2.3 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain TAXi_N PF14543.6 EGF99499.1 - 1 9.6 5.3 1 9.6 5.3 1.2 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal TraG-D_C PF12696.7 EGF99502.1 - 0.8 9.7 5.0 17 5.4 0.1 2.2 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG DUF3446 PF11928.8 EGF99502.1 - 1.6 9.1 12.6 1.4 9.3 0.1 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Tht1 PF04163.12 EGF99505.1 - 2.4e-07 29.9 2.7 2.6e-07 29.8 0.1 1.9 2 0 0 2 2 2 1 Tht1-like nuclear fusion protein Baculo_PEP_C PF04513.12 EGF99505.1 - 0.42 10.6 7.6 2.1 8.4 0.1 3.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ThrE PF06738.12 EGF99506.1 - 7.2e-35 120.5 7.0 7.2e-35 120.5 7.0 2.6 3 1 0 3 3 3 1 Putative threonine/serine exporter ThrE_2 PF12821.7 EGF99506.1 - 7.1e-06 26.2 4.5 7.1e-06 26.2 4.5 2.4 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE DUF4524 PF15025.6 EGF99507.1 - 0.013 15.2 0.4 0.014 15.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) Guanylin PF02058.15 EGF99507.1 - 0.092 13.2 0.1 0.16 12.5 0.1 1.4 1 1 0 1 1 1 0 Guanylin precursor MRP-L27 PF09809.9 EGF99509.1 - 4.1e-06 26.6 0.7 3.4e-05 23.6 0.4 2.3 2 1 0 2 2 2 1 Mitochondrial ribosomal protein L27 RCS1 PF07326.11 EGF99513.1 - 0.034 14.1 5.5 0.049 13.6 5.5 1.2 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 KH_1 PF00013.29 EGF99514.1 - 5.7e-43 144.6 13.0 2.8e-17 62.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGF99514.1 - 1e-11 44.5 10.8 0.005 16.6 0.7 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 EGF99514.1 - 3.4e-09 36.4 1.4 0.021 14.7 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EGF99514.1 - 0.00013 21.9 7.3 0.16 12.1 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 EGF99514.1 - 0.029 14.4 0.0 6.2 6.9 0.0 2.3 2 0 0 2 2 2 0 KH-like RNA-binding domain CSD PF00313.22 EGF99515.1 - 6.4e-13 48.4 0.1 3.7e-12 45.9 0.1 2.0 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain DUF4456 PF14644.6 EGF99516.1 - 0.046 13.4 0.3 0.071 12.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) WLM PF08325.10 EGF99517.1 - 1.3e-27 97.1 0.1 1.3e-27 97.1 0.1 1.6 2 0 0 2 2 2 1 WLM domain UPA_2 PF17809.1 EGF99517.1 - 0.072 12.9 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 UPA domain EBV-NA3 PF05009.12 EGF99518.1 - 0.23 10.9 2.6 0.26 10.8 1.3 1.7 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Presenilin PF01080.17 EGF99518.1 - 3.7 6.2 5.1 5.1 5.8 5.1 1.2 1 0 0 1 1 1 0 Presenilin Hexapep_2 PF14602.6 EGF99518.1 - 3.9 7.3 8.7 10 6.0 3.3 3.0 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Med13_C PF06333.12 EGF99518.1 - 4.8 6.4 12.5 7.8 5.7 12.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain SEP PF08059.13 EGF99520.1 - 2.7e-23 82.3 0.0 7.7e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EGF99520.1 - 5.4e-14 52.2 0.0 9.9e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EGF99520.1 - 9.1e-12 44.6 0.1 1.8e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain OB_aCoA_assoc PF01796.17 EGF99520.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 DUF35 OB-fold domain, acyl-CoA-associated TAP_C PF03943.13 EGF99520.1 - 0.21 11.2 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 TAP C-terminal domain Terminase_2 PF03592.16 EGF99523.1 - 0.061 13.8 0.7 0.15 12.6 0.7 1.6 1 0 0 1 1 1 0 Terminase small subunit Rab5ip PF07019.12 EGF99524.1 - 7.4e-20 71.3 12.3 9.3e-20 71.0 12.3 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF3932 PF13068.6 EGF99524.1 - 7.9 6.8 13.9 0.21 11.9 3.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3932) LSM PF01423.22 EGF99525.1 - 6.3e-19 67.4 0.1 6.7e-19 67.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain CxC1 PF18802.1 EGF99526.1 - 1.3e-11 44.5 0.7 2.5e-11 43.6 0.1 1.8 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGF99526.1 - 0.0029 17.3 0.0 0.0064 16.1 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase tRNA_lig_CPD PF08302.11 EGF99527.1 - 0.1 12.0 0.4 0.14 11.6 0.4 1.1 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Cutinase PF01083.22 EGF99528.1 - 1.3e-25 90.4 2.9 1.7e-25 90.0 2.9 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 EGF99528.1 - 0.023 14.4 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 EGF99528.1 - 0.15 11.6 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF2034 PF10356.9 EGF99530.1 - 2.9e-09 36.6 0.0 0.0017 17.8 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) IMUP PF15761.5 EGF99533.1 - 2.2 9.0 9.4 5.7 7.7 9.4 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein LolA_like PF17131.4 EGF99534.1 - 0.058 13.1 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein PEX11 PF05648.14 EGF99538.1 - 9.8e-07 28.5 0.5 7.4e-06 25.6 0.5 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Prefoldin_2 PF01920.20 EGF99539.1 - 0.057 13.4 0.8 0.057 13.4 0.8 3.0 3 1 1 4 4 4 0 Prefoldin subunit SlyX PF04102.12 EGF99539.1 - 0.14 12.8 4.7 0.67 10.6 4.7 2.2 1 0 0 1 1 1 0 SlyX XhlA PF10779.9 EGF99539.1 - 0.24 11.6 3.3 0.45 10.7 2.0 2.2 2 1 0 2 2 2 0 Haemolysin XhlA Troponin PF00992.20 EGF99539.1 - 7.7 6.8 9.5 1.3 9.3 1.1 2.6 2 0 0 2 2 2 0 Troponin MGC-24 PF05283.11 EGF99540.1 - 0.32 11.4 3.3 0.49 10.8 3.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Med4 PF10018.9 EGF99542.1 - 0.049 13.3 1.0 0.071 12.8 1.0 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 HypA PF01155.19 EGF99542.1 - 1.6 8.8 7.3 0.27 11.3 0.6 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4451 PF14616.6 EGF99543.1 - 6.8e-10 39.2 1.4 3.6e-09 36.9 1.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) Asp PF00026.23 EGF99545.1 - 7.8e-09 35.4 0.8 2e-06 27.4 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF99545.1 - 0.0022 18.3 0.3 0.22 11.7 0.1 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Helitron_like_N PF14214.6 EGF99547.1 - 0.032 14.5 0.5 0.091 13.0 0.2 2.0 2 1 0 2 2 2 0 Helitron helicase-like domain at N-terminus DUF3402 PF11882.8 EGF99548.1 - 7.1e-120 401.2 11.0 1.6e-117 393.5 11.0 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EGF99548.1 - 8.1e-67 225.4 0.0 2.9e-66 223.6 0.0 1.8 2 0 0 2 2 2 1 N1221-like protein GCP5-Mod21 PF14609.6 EGF99548.1 - 0.037 12.4 1.1 0.058 11.7 1.1 1.2 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Herpes_capsid PF06112.11 EGF99548.1 - 0.47 10.5 10.5 1.6 8.8 10.5 1.9 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ras PF00071.22 EGF99549.1 - 1.4e-55 187.3 0.0 1.6e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF99549.1 - 1.6e-21 76.7 0.0 2.2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF99549.1 - 7.4e-07 28.8 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGF99549.1 - 0.0075 15.7 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 EGF99549.1 - 0.046 12.9 0.0 0.45 9.7 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain CHZ PF09649.10 EGF99549.1 - 0.19 11.2 1.0 0.37 10.3 1.0 1.5 1 0 0 1 1 1 0 Histone chaperone domain CHZ Gtr1_RagA PF04670.12 EGF99549.1 - 0.23 10.8 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Nipped-B_C PF12830.7 EGF99550.1 - 3.7e-41 141.2 2.2 4e-41 141.0 0.1 2.3 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus IBN_N PF03810.19 EGF99551.1 - 4.8e-13 48.8 0.0 7.4e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT PF02985.22 EGF99552.1 - 0.049 13.9 0.1 0.33 11.3 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat GrpE PF01025.19 EGF99552.1 - 0.16 11.6 0.0 9.7 5.8 0.0 2.4 1 1 1 2 2 2 0 GrpE Peroxidase_2 PF01328.17 EGF99554.1 - 3e-43 148.6 0.0 4.1e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 EGF99555.1 - 8.9e-41 140.5 0.0 1.2e-40 140.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 RED_C PF07807.11 EGF99555.1 - 0.07 13.6 0.3 0.17 12.3 0.3 1.6 1 1 1 2 2 2 0 RED-like protein C-terminal region UPF0016 PF01169.19 EGF99556.1 - 8.4e-41 138.2 21.2 5.4e-21 74.7 7.5 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 EGF99556.1 - 0.00061 19.6 6.5 0.023 14.4 0.2 2.3 2 0 0 2 2 2 2 Putative manganese efflux pump G3P_acyltransf PF02660.15 EGF99556.1 - 0.005 16.9 3.1 0.005 16.9 3.1 2.2 2 0 0 2 2 2 1 Glycerol-3-phosphate acyltransferase LysE PF01810.18 EGF99556.1 - 0.017 14.6 3.1 0.017 14.6 3.1 2.3 2 0 0 2 2 2 0 LysE type translocator HXXEE PF13787.6 EGF99556.1 - 0.84 10.5 5.1 3.5 8.5 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif DUF373 PF04123.13 EGF99556.1 - 0.98 8.8 6.3 2 7.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Pkinase PF00069.25 EGF99557.1 - 4.2e-63 213.2 0.0 4.7e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF99557.1 - 2.3e-40 138.5 0.0 2.7e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF99557.1 - 0.00022 20.1 0.0 0.00036 19.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGF99557.1 - 0.0017 18.3 0.0 0.4 10.6 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 EGF99557.1 - 0.0066 16.1 0.4 1.5 8.4 0.1 2.1 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGF99557.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MSP1a PF11670.8 EGF99559.1 - 0.069 12.4 0.0 0.078 12.3 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF3038 PF11237.8 EGF99559.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) Endomucin PF07010.12 EGF99560.1 - 0.24 11.3 19.1 0.31 11.0 19.1 1.2 1 0 0 1 1 1 0 Endomucin FXMRP1_C_core PF12235.8 EGF99560.1 - 0.26 11.9 15.7 0.91 10.2 11.5 2.2 1 1 1 2 2 2 0 Fragile X-related 1 protein core C terminal Plasmodium_Vir PF05795.11 EGF99560.1 - 4.2 6.7 5.5 5 6.4 5.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3533 PF12051.8 EGF99560.1 - 6.6 5.5 6.0 8.6 5.2 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF4407 PF14362.6 EGF99560.1 - 7.5 5.8 8.8 9.8 5.4 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lysis_col PF02402.16 EGF99566.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Lysis protein MBOAT_2 PF13813.6 EGF99567.1 - 1.7e-13 50.6 3.7 3.8e-13 49.5 3.1 2.0 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family ATG27 PF09451.10 EGF99567.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 RsfS PF02410.15 EGF99568.1 - 5e-12 46.1 0.0 8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Lipase_GDSL PF00657.22 EGF99570.1 - 0.00079 19.5 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EGF99570.1 - 0.0014 19.0 0.1 0.0017 18.8 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AFT PF08731.11 EGF99571.1 - 0.00052 20.4 0.8 0.0014 19.0 0.8 1.8 1 1 0 1 1 1 1 Transcription factor AFT COX4 PF02936.14 EGF99572.1 - 0.1 12.6 0.1 0.1 12.6 0.1 1.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV KDZ PF18758.1 EGF99573.1 - 4.4e-21 75.5 0.0 6.1e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGF99573.1 - 9.2e-15 54.7 0.1 2.1e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGF99573.1 - 0.0022 18.1 0.0 0.0037 17.4 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGF99573.1 - 0.0087 15.9 0.1 0.05 13.5 0.1 2.0 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases Prefoldin PF02996.17 EGF99574.1 - 0.031 14.2 2.7 0.46 10.4 0.4 2.3 2 0 0 2 2 2 0 Prefoldin subunit FXR_C1 PF16096.5 EGF99574.1 - 0.21 11.8 2.2 0.46 10.7 2.2 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 MIP-T3_C PF17749.1 EGF99574.1 - 1.1 9.2 10.4 0.07 13.1 4.8 2.0 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region EMP24_GP25L PF01105.24 EGF99574.1 - 5.5 6.9 8.1 1.9 8.4 2.9 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Phosducin PF02114.16 EGF99577.1 - 1.9e-07 30.3 0.2 2.3e-07 30.0 0.2 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EGF99577.1 - 1.9e-05 24.6 0.0 4.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.16 EGF99577.1 - 0.019 14.8 0.3 0.028 14.2 0.3 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 tRNA-synt_2 PF00152.20 EGF99578.1 - 6.9e-76 255.3 0.0 1.1e-75 254.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGF99578.1 - 3.8e-06 26.8 0.1 6.9e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CDPS PF16715.5 EGF99578.1 - 0.057 13.1 3.1 0.17 11.5 2.8 1.9 2 0 0 2 2 2 0 Cyclodipeptide synthase DUF3824 PF12868.7 EGF99578.1 - 0.27 11.9 5.6 0.52 11.0 5.6 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF1682 PF07946.14 EGF99578.1 - 4.9 6.3 9.7 8 5.6 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Tubulin-binding PF00418.19 EGF99580.1 - 0.15 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat DUF4641 PF15483.6 EGF99583.1 - 5.8 5.9 10.6 8.8 5.3 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) Forkhead PF00250.18 EGF99584.1 - 8.8e-17 61.2 0.0 9.3e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain DUF3874 PF12990.7 EGF99584.1 - 0.04 14.2 0.0 0.22 11.9 0.0 1.9 1 1 1 2 2 2 0 Domain of unknonw function from B. Theta Gene description (DUF3874) HARE-HTH PF05066.13 EGF99584.1 - 0.15 12.4 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain AA_permease_2 PF13520.6 EGF99585.1 - 3.3e-57 194.2 47.5 4.1e-57 193.9 47.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGF99585.1 - 3.9e-13 48.8 37.2 5.3e-13 48.4 37.2 1.1 1 0 0 1 1 1 1 Amino acid permease GHMP_kinases_N PF00288.26 EGF99586.1 - 7.2e-13 48.6 0.0 1.8e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGF99586.1 - 1.8e-12 47.4 0.0 3.9e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal DnaJ PF00226.31 EGF99589.1 - 5.9e-18 64.8 0.0 2.6e-17 62.7 0.0 2.3 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 EGF99589.1 - 7.3e-08 32.0 0.4 0.022 14.8 0.1 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGF99589.1 - 3.1e-06 26.8 2.9 0.58 10.1 0.2 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGF99589.1 - 9.5e-05 23.0 1.2 0.38 11.4 0.3 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGF99589.1 - 0.0004 20.1 1.1 2.7 8.0 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF99589.1 - 0.0039 17.3 1.4 9.9 6.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGF99589.1 - 0.014 15.7 8.2 0.42 10.9 0.4 4.1 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF99589.1 - 0.015 15.3 0.6 3.7 7.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGF99589.1 - 0.02 14.5 0.6 0.28 10.9 0.7 2.7 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 EGF99589.1 - 0.021 15.6 1.5 1.1e+02 4.0 0.0 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat Myb_DNA-bind_3 PF12776.7 EGF99589.1 - 0.057 14.4 1.5 16 6.5 0.0 3.3 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain TPR_19 PF14559.6 EGF99589.1 - 0.53 10.8 4.6 0.81 10.2 0.2 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF99589.1 - 6 7.7 8.8 2.4 9.0 0.1 4.3 6 0 0 6 6 4 0 Tetratricopeptide repeat LRR_4 PF12799.7 EGF99593.1 - 0.035 14.5 1.2 0.27 11.7 1.2 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF99593.1 - 1.4 8.7 6.9 0.26 11.1 2.0 2.2 2 0 0 2 2 2 0 Leucine rich repeat zf-CCHC_6 PF15288.6 EGF99594.1 - 0.16 11.8 6.7 0.087 12.7 4.0 1.9 2 0 0 2 2 2 0 Zinc knuckle PBP1_TM PF14812.6 EGF99597.1 - 0.97 9.9 5.2 2.3 8.6 5.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tctex-1 PF03645.13 EGF99599.1 - 0.0014 18.8 0.0 0.0015 18.7 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF4199 PF13858.6 EGF99600.1 - 1.5 9.2 4.8 3.4 8.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) His_biosynth PF00977.21 EGF99601.1 - 2.1e-29 102.7 0.0 2.7e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Sod_Fe_C PF02777.18 EGF99602.1 - 1.9e-15 56.9 0.0 1.4e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain SUIM_assoc PF16619.5 EGF99602.1 - 0.055 13.5 0.2 0.21 11.7 0.1 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 adh_short PF00106.25 EGF99603.1 - 3e-40 137.8 0.0 3.8e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGF99603.1 - 1.7e-25 90.0 0.0 2.2e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF99603.1 - 6.9e-12 45.6 0.8 1.1e-10 41.8 0.8 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGF99603.1 - 0.00011 21.7 0.0 0.00019 21.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGF99603.1 - 0.058 12.5 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 EGF99603.1 - 0.085 11.8 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Endonuclease_7 PF02945.15 EGF99603.1 - 0.11 12.4 0.2 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 Recombination endonuclease VII NAD_binding_10 PF13460.6 EGF99603.1 - 0.12 12.3 0.0 0.58 10.0 0.0 1.9 1 1 0 1 1 1 0 NAD(P)H-binding CDC73_C PF05179.14 EGF99604.1 - 0.033 13.9 0.1 0.065 12.9 0.1 1.4 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal Phe_hydrox_dim PF07976.12 EGF99604.1 - 0.052 13.6 0.1 0.083 12.9 0.1 1.4 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain RIO1 PF01163.22 EGF99605.1 - 1.6e-11 44.1 0.0 2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGF99605.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 EGF99605.1 - 0.015 14.6 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase_fungal PF17667.1 EGF99605.1 - 0.057 12.2 0.0 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGF99605.1 - 0.18 11.7 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_4 PF12799.7 EGF99607.1 - 0.005 17.2 1.5 0.055 13.9 0.8 2.9 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGF99607.1 - 0.012 15.5 0.4 0.043 13.7 0.4 2.0 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EGF99607.1 - 0.076 12.9 2.9 0.87 9.5 0.2 2.9 2 0 0 2 2 2 0 F-box domain PIN_4 PF13638.6 EGF99609.1 - 2.7e-12 47.1 0.0 7.8e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 PIN domain Pkr1 PF08636.10 EGF99611.1 - 2.9e-25 88.2 2.8 3.6e-25 87.9 2.8 1.1 1 0 0 1 1 1 1 ER protein Pkr1 UbiA PF01040.18 EGF99611.1 - 0.019 14.3 1.8 0.024 14.0 1.8 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family SLATT_1 PF18181.1 EGF99611.1 - 0.031 14.2 0.1 0.036 14.0 0.1 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Pescadillo_N PF06732.11 EGF99612.1 - 2.4e-120 401.2 0.1 2.4e-120 401.2 0.1 2.0 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EGF99612.1 - 1.5e-10 41.3 0.0 3.8e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGF99612.1 - 2.8e-06 27.6 0.0 5.3e-05 23.5 0.0 3.0 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain AD PF09793.9 EGF99613.1 - 7.6e-21 74.0 0.0 1.6e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain RNA_POL_M_15KD PF02150.16 EGF99614.1 - 2.6e-12 46.4 1.1 2.6e-12 46.4 1.1 2.5 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 EGF99614.1 - 8.4e-10 38.3 2.7 8.4e-10 38.3 2.7 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 EGF99614.1 - 0.0053 16.7 6.4 0.84 9.7 0.4 2.5 2 1 0 2 2 2 2 Double zinc ribbon Elf1 PF05129.13 EGF99614.1 - 0.03 14.4 2.1 0.16 12.0 0.2 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 EGF99614.1 - 0.04 13.9 1.2 0.04 13.9 1.2 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 EGF99614.1 - 0.046 13.8 7.7 4.2 7.6 0.0 3.7 4 0 0 4 4 4 0 Zinc ribbon domain DUF3268 PF11672.8 EGF99614.1 - 0.055 13.8 0.5 0.055 13.8 0.5 2.0 2 0 0 2 2 2 0 zinc-finger-containing domain DUF3795 PF12675.7 EGF99614.1 - 0.067 13.6 3.0 0.13 12.7 1.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) Rpr2 PF04032.16 EGF99614.1 - 0.095 13.0 1.7 0.77 10.1 1.7 2.1 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_UBOX PF13445.6 EGF99614.1 - 0.23 11.5 6.1 44 4.2 0.2 4.0 4 0 0 4 4 4 0 RING-type zinc-finger Lar_restr_allev PF14354.6 EGF99614.1 - 0.62 10.5 6.6 0.73 10.3 0.2 2.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 EGF99614.1 - 1.1 8.9 8.6 0.18 11.3 2.0 2.9 3 1 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_10 PF10058.9 EGF99614.1 - 2.7 7.8 10.3 4.8 7.0 1.9 2.7 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein eRF1_1 PF03463.15 EGF99615.1 - 9.7e-40 135.6 0.0 1.7e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 EGF99615.1 - 1.4e-20 73.8 0.0 3.2e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 EGF99615.1 - 2.6e-14 53.7 0.1 4.6e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 EMP24_GP25L PF01105.24 EGF99618.1 - 3.9e-19 69.3 0.1 4.2e-19 69.2 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MAT1 PF06391.13 EGF99619.1 - 0.0094 15.8 6.7 0.016 15.1 6.7 1.3 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 GAGA_bind PF06217.12 EGF99619.1 - 0.016 15.6 2.1 0.016 15.5 2.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.17 EGF99619.1 - 0.83 8.4 3.6 0.92 8.2 3.6 1.1 1 0 0 1 1 1 0 Presenilin SPT6_acidic PF14632.6 EGF99619.1 - 0.93 10.1 9.2 0.28 11.8 5.9 1.9 2 1 0 2 2 2 0 Acidic N-terminal SPT6 JmjC PF02373.22 EGF99620.1 - 4.7e-13 49.6 0.7 2.4e-12 47.3 0.1 2.5 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGF99620.1 - 0.02 14.6 0.1 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Cupin-like domain Zn_ribbon_17 PF17120.5 EGF99620.1 - 0.27 10.9 8.4 0.73 9.5 8.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 EGF99620.1 - 1.7 8.6 10.1 0.16 11.9 4.8 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1664 PF07889.12 EGF99623.1 - 0.0012 18.9 7.5 4.8 7.2 0.6 4.5 1 1 3 4 4 4 2 Protein of unknown function (DUF1664) DUF3584 PF12128.8 EGF99623.1 - 0.0024 15.5 19.3 0.0034 15.0 18.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) Foie-gras_1 PF11817.8 EGF99623.1 - 0.027 14.1 4.5 1.4 8.5 0.7 2.3 2 0 0 2 2 2 0 Foie gras liver health family 1 Arteri_nsp7a PF16749.5 EGF99623.1 - 0.14 12.4 1.3 25 5.1 0.0 2.8 2 1 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha Zeta_toxin PF06414.12 EGF99623.1 - 0.17 11.1 8.2 0.29 10.4 0.5 2.6 2 1 0 2 2 2 0 Zeta toxin YusW PF14039.6 EGF99623.1 - 0.22 12.1 1.7 15 6.2 0.2 2.6 2 0 0 2 2 2 0 YusW-like protein IF-2B PF01008.17 EGF99623.1 - 1.3 8.2 4.6 4.5 6.4 4.6 1.9 1 1 0 1 1 1 0 Initiation factor 2 subunit family DUF883 PF05957.13 EGF99623.1 - 1.5 9.5 16.0 2.8 8.6 2.0 3.6 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) TPR_MLP1_2 PF07926.12 EGF99623.1 - 2.3 8.3 25.0 0.6 10.2 3.8 3.7 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein CAP18_C PF12153.8 EGF99623.1 - 4.5 7.2 5.1 65 3.5 0.1 3.6 3 0 0 3 3 3 0 LPS binding domain of CAP18 (C terminal) Pkinase PF00069.25 EGF99624.1 - 3.9e-17 62.5 0.0 5.1e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF99624.1 - 3e-10 39.8 0.0 3.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RRP36 PF06102.12 EGF99628.1 - 0.019 14.9 2.5 0.035 14.1 2.5 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Imm43 PF15570.6 EGF99628.1 - 0.032 14.2 1.6 0.53 10.3 0.4 2.3 2 0 0 2 2 2 0 Immunity protein 43 DUF3106 PF11304.8 EGF99628.1 - 0.036 14.5 1.3 0.064 13.7 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) FliG_N PF14842.6 EGF99628.1 - 0.13 12.9 0.9 0.27 11.8 0.5 1.8 2 0 0 2 2 2 0 FliG N-terminal domain MRP-S23 PF10484.9 EGF99628.1 - 0.42 10.9 3.4 0.29 11.4 1.6 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 Fez1 PF06818.15 EGF99629.1 - 0.0078 16.7 13.3 0.0078 16.7 13.3 2.0 1 1 1 2 2 2 1 Fez1 DLP_helical PF18709.1 EGF99629.1 - 0.039 13.1 10.9 0.34 10.1 1.3 2.9 2 2 1 3 3 3 0 Dynamin-like helical domain DUF842 PF05811.13 EGF99629.1 - 0.049 13.3 4.7 0.67 9.6 4.2 2.5 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) H-kinase_dim PF02895.14 EGF99629.1 - 0.96 9.9 9.7 2.5 8.6 6.2 3.0 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain CLZ PF16526.5 EGF99629.1 - 2.1 8.8 13.7 16 5.9 2.8 4.1 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 EGF99629.1 - 2.6 8.1 13.7 2.3 8.3 1.5 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 EGF99629.1 - 3.6 7.4 14.2 0.2 11.4 1.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF745 PF05335.13 EGF99629.1 - 4.5 6.9 13.4 1.7 8.3 4.2 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF745) DNA_pol_delta_4 PF04081.13 EGF99629.1 - 5.7 7.3 7.0 1.9 8.8 2.3 2.2 1 1 0 2 2 2 0 DNA polymerase delta, subunit 4 DUF16 PF01519.16 EGF99629.1 - 6.1 7.4 10.9 0.36 11.3 1.4 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 bZIP_2 PF07716.15 EGF99629.1 - 6.8 6.9 12.9 8.1 6.6 1.2 3.3 3 0 0 3 3 3 0 Basic region leucine zipper Matrilin_ccoil PF10393.9 EGF99630.1 - 0.076 12.9 5.8 0.086 12.7 0.8 2.6 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1644 PF07800.12 EGF99630.1 - 0.24 11.5 2.5 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) DUF1664 PF07889.12 EGF99630.1 - 1.6 8.8 3.9 2.6 8.1 3.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) KxDL PF10241.9 EGF99630.1 - 2.8 8.3 18.0 0.43 10.9 7.1 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein Nsp1_C PF05064.13 EGF99630.1 - 5.4 6.8 10.6 3.9 7.3 4.8 2.7 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF3818 PF12825.7 EGF99633.1 - 5.5e-63 213.0 8.6 2.1e-54 184.8 8.6 2.3 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EGF99633.1 - 9.1e-06 25.7 0.0 0.00014 21.9 0.0 2.7 2 1 0 2 2 2 1 PX-associated HTH_Tnp_1 PF01527.20 EGF99633.1 - 0.029 14.7 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.6 EGF99633.1 - 0.044 13.6 1.9 0.081 12.7 0.7 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Chitin_synth_1 PF01644.17 EGF99634.1 - 2.9e-63 212.7 0.0 4.5e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGF99634.1 - 1.5e-26 92.1 0.0 2.8e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGF99634.1 - 4.4e-23 81.7 0.0 3.4e-19 68.9 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGF99634.1 - 3.4e-09 36.9 0.1 3.4e-09 36.9 0.1 2.4 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Psu PF07455.11 EGF99634.1 - 0.0023 17.6 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Phage polarity suppression protein (Psu) DUF3629 PF12302.8 EGF99635.1 - 0.045 13.2 1.1 0.073 12.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) FANCI_S1-cap PF14674.6 EGF99635.1 - 0.28 11.3 0.7 0.63 10.2 0.7 1.5 1 0 0 1 1 1 0 FANCI solenoid 1 cap SNase PF00565.17 EGF99636.1 - 7.8e-57 190.4 0.0 8.6e-21 74.4 0.0 7.0 5 2 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EGF99636.1 - 2.7e-20 72.6 0.0 5.3e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EGF99636.1 - 0.0013 18.1 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 EGF99636.1 - 0.0052 17.2 0.1 0.49 10.9 0.0 3.0 3 0 0 3 3 3 1 Agenet domain DUF3818 PF12825.7 EGF99637.1 - 9.3e-62 209.0 6.0 2.2e-61 207.8 4.3 2.1 1 1 1 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EGF99637.1 - 1.6e-26 92.8 0.3 4.1e-26 91.5 0.3 1.7 1 0 0 1 1 1 1 PX-associated Tma16 PF11176.8 EGF99639.1 - 1.6e-43 148.0 0.1 2.2e-43 147.6 0.1 1.2 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Ribosomal_S17e PF00833.18 EGF99639.1 - 0.058 13.3 1.6 0.12 12.3 0.1 2.2 2 0 0 2 2 2 0 Ribosomal S17 PHP PF02811.19 EGF99640.1 - 1.2e-13 51.8 0.5 2.1e-13 50.9 0.5 1.4 1 1 0 1 1 1 1 PHP domain F-box-like PF12937.7 EGF99641.1 - 1.3e-08 34.6 0.5 2.9e-08 33.5 0.5 1.7 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 EGF99641.1 - 3e-07 30.0 0.2 0.034 14.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGF99641.1 - 3.9e-07 29.6 0.3 0.43 10.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat F-box PF00646.33 EGF99641.1 - 3.8e-06 26.6 0.8 1.3e-05 24.9 0.2 2.2 2 0 0 2 2 2 1 F-box domain TPR_12 PF13424.6 EGF99641.1 - 0.00048 20.4 0.1 0.28 11.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF99641.1 - 0.0026 17.4 0.0 1.4 8.6 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 EGF99641.1 - 0.0048 17.6 0.3 4.6 8.3 0.0 3.7 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF99641.1 - 0.056 13.7 0.3 8.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGF99641.1 - 0.1 12.8 0.0 0.41 10.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF99641.1 - 0.17 12.0 0.0 16 5.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.7 EGF99641.1 - 0.3 11.6 4.7 6 7.4 0.0 4.7 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) DUF563 PF04577.14 EGF99643.1 - 3.2e-16 60.1 0.0 7.9e-16 58.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF563) SKN1 PF03935.15 EGF99644.1 - 2.2e-191 636.6 6.5 2.5e-191 636.5 6.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GAS2 PF02187.17 EGF99645.1 - 3.3e-09 36.7 0.5 1.1e-08 35.0 0.5 1.9 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain NusB PF01029.18 EGF99645.1 - 0.13 12.5 3.2 1.8 8.8 0.1 3.7 2 0 0 2 2 2 0 NusB family SH2_2 PF14633.6 EGF99647.1 - 4.3e-81 271.4 0.1 4.3e-81 271.4 0.1 2.0 2 0 0 2 2 1 1 SH2 domain HHH_7 PF14635.6 EGF99647.1 - 1.2e-34 118.7 0.2 4e-34 117.1 0.2 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 EGF99647.1 - 8.3e-26 90.7 0.3 2.5e-25 89.2 0.3 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 EGF99647.1 - 6.3e-23 81.2 0.0 4.6e-22 78.4 0.0 2.4 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 EGF99647.1 - 1.5e-18 67.2 26.5 1.5e-18 67.2 26.5 3.9 4 0 0 4 4 3 2 Acidic N-terminal SPT6 HHH_3 PF12836.7 EGF99647.1 - 9.8e-07 29.0 0.0 8.8e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif SH2 PF00017.24 EGF99647.1 - 1.4e-06 28.3 0.0 5e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 EGF99647.1 - 7.4e-06 26.8 0.8 5.7e-05 23.9 0.8 2.7 1 1 0 1 1 1 1 HHH domain Tex_N PF09371.10 EGF99647.1 - 0.0015 18.2 0.0 0.0068 16.1 0.0 2.1 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Ovate PF04844.13 EGF99647.1 - 0.047 13.7 0.1 0.15 12.1 0.1 1.9 1 0 0 1 1 1 0 Transcriptional repressor, ovate S1 PF00575.23 EGF99647.1 - 0.11 12.8 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 S1 RNA binding domain REF PF05755.12 EGF99647.1 - 0.14 12.0 0.2 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) HMG_box PF00505.19 EGF99649.1 - 3.8e-13 49.6 1.6 3.8e-13 49.6 1.6 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGF99649.1 - 0.0021 18.6 0.2 0.0053 17.3 0.2 1.7 1 0 0 1 1 1 1 HMG-box domain CLTH PF10607.9 EGF99650.1 - 3e-16 59.6 0.1 3.3e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EGF99650.1 - 1e-08 35.0 1.0 6.2e-07 29.3 0.1 2.6 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.12 EGF99650.1 - 0.00023 20.6 0.0 0.00046 19.6 0.0 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 EGF99650.1 - 0.0004 20.3 2.4 0.012 15.5 0.2 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGF99650.1 - 0.036 13.9 0.5 0.036 13.9 0.5 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF99650.1 - 0.041 14.2 0.2 0.041 14.2 0.2 2.7 3 0 0 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.6 EGF99650.1 - 0.068 13.0 3.2 0.15 11.9 0.8 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGF99650.1 - 0.079 12.8 1.5 0.13 12.1 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF99650.1 - 0.23 11.3 2.7 0.32 10.9 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EGF99650.1 - 1.8 8.5 5.4 0.56 10.1 1.1 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit CENP-T_C PF15511.6 EGF99652.1 - 4.8e-08 33.1 0.1 5.9e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EGF99652.1 - 8.4e-05 22.7 0.1 0.00012 22.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGF99652.1 - 0.00018 21.9 0.0 0.00023 21.5 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EGF99652.1 - 0.0011 19.4 0.1 0.0012 19.2 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGF99652.1 - 0.0015 18.7 0.1 0.0029 17.8 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGF99652.1 - 0.073 13.2 0.0 0.082 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_L27A PF00828.19 EGF99652.1 - 0.45 11.2 4.0 0.57 10.9 4.0 1.3 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF2491 PF10679.9 EGF99653.1 - 0.028 13.6 0.6 0.04 13.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Phage_holin_6_1 PF09682.10 EGF99653.1 - 0.68 10.4 3.5 1.2 9.6 3.5 1.3 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Arylesterase PF01731.20 EGF99654.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Arylesterase DUF885 PF05960.11 EGF99656.1 - 0.077 12.6 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) RhoGAP PF00620.27 EGF99657.1 - 0.00064 19.6 0.0 0.00065 19.6 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain S1 PF00575.23 EGF99658.1 - 1.2e-34 118.5 9.3 7.1e-11 42.3 0.0 10.6 10 2 1 11 11 11 4 S1 RNA binding domain TPR_19 PF14559.6 EGF99658.1 - 5.3e-10 39.7 0.0 0.00074 20.0 0.0 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGF99658.1 - 2.1e-05 25.0 0.0 0.12 13.3 0.0 4.6 4 1 1 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF99658.1 - 8.2e-05 22.8 0.3 0.0018 18.5 0.3 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGF99658.1 - 8.9e-05 22.9 0.1 0.071 13.8 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGF99658.1 - 0.00015 22.4 0.0 0.18 12.5 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 EGF99658.1 - 0.0016 18.3 0.0 6.6 6.8 0.0 4.1 3 1 0 3 3 3 1 RNase II-type exonuclease C-terminal S1 domain NRDE-2 PF08424.10 EGF99658.1 - 0.0017 17.5 10.0 0.047 12.8 7.9 2.5 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 EGF99658.1 - 0.0022 17.2 2.7 0.015 14.5 2.1 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 EGF99658.1 - 0.032 13.9 2.0 0.21 11.3 0.5 3.1 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_2 PF07719.17 EGF99658.1 - 0.032 14.3 0.1 1.2 9.4 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGF99658.1 - 0.08 13.2 0.1 2.3 8.6 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SDA1 PF05285.12 EGF99658.1 - 0.28 10.6 17.4 0.058 12.8 8.5 2.3 2 0 0 2 2 2 0 SDA1 Suf PF05843.14 EGF99658.1 - 1 9.3 18.8 0.46 10.4 0.1 3.9 3 1 1 4 4 4 0 Suppressor of forked protein (Suf) MTS PF05175.14 EGF99660.1 - 3.1e-09 36.6 0.0 1.6e-08 34.2 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.18 EGF99660.1 - 0.017 14.9 0.0 0.037 13.7 0.0 1.5 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 EGF99660.1 - 0.063 14.0 0.0 0.12 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGF99660.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGF99660.1 - 0.18 12.5 0.0 0.31 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 2TM PF13239.6 EGF99661.1 - 0.034 14.5 1.0 0.053 13.8 1.0 1.3 1 0 0 1 1 1 0 2TM domain Glyco_transf_90 PF05686.12 EGF99663.1 - 8e-08 31.6 0.3 0.0019 17.2 0.0 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 SPX PF03105.19 EGF99663.1 - 1 9.2 6.3 0.4 10.5 1.0 2.2 2 0 0 2 2 2 0 SPX domain DnaJ PF00226.31 EGF99665.1 - 1.5e-09 37.9 0.1 7.4e-09 35.6 0.0 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 EGF99665.1 - 9.7e-06 26.0 0.2 0.17 12.4 0.1 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat SPO22 PF08631.10 EGF99665.1 - 0.0074 15.8 0.3 0.035 13.6 0.1 2.0 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.6 EGF99665.1 - 0.0085 16.8 0.3 20 6.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF99665.1 - 0.013 15.5 0.4 8.7 6.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1158 PF06643.11 EGF99669.1 - 0.088 13.3 0.6 0.31 11.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1158) Sad1_UNC PF07738.13 EGF99670.1 - 1.2e-30 106.2 0.0 2.3e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CHDCT2 PF08074.11 EGF99670.1 - 0.00015 22.0 0.7 0.46 10.6 0.1 2.2 2 0 0 2 2 2 2 CHDCT2 (NUC038) domain Epsilon_antitox PF08998.11 EGF99670.1 - 0.03 14.6 0.8 0.058 13.7 0.1 1.8 2 0 0 2 2 2 0 Bacterial epsilon antitoxin BLOC1_2 PF10046.9 EGF99670.1 - 0.04 14.2 1.9 0.047 14.0 0.8 1.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RhoGEF PF00621.20 EGF99670.1 - 0.075 13.3 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 RhoGEF domain NPV_P10 PF05531.12 EGF99670.1 - 0.19 12.2 0.9 0.62 10.6 0.8 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Phage_int_SAM_6 PF18644.1 EGF99670.1 - 0.26 11.3 2.5 0.66 10.0 0.1 2.6 2 1 1 3 3 3 0 Phage integrase SAM-like domain HSBP1 PF06825.12 EGF99670.1 - 0.43 10.5 1.9 0.4 10.6 0.2 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 PRANC PF09372.10 EGF99671.1 - 0.076 13.3 0.6 0.16 12.3 0.2 1.7 1 1 1 2 2 2 0 PRANC domain Lys-AminoMut_A PF09043.11 EGF99671.1 - 0.15 10.5 0.0 0.19 10.1 0.0 1.0 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Ribosomal_L14 PF00238.19 EGF99673.1 - 2.2e-44 150.5 0.5 2.4e-44 150.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e GvpO PF05800.11 EGF99673.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO Peroxidase_2 PF01328.17 EGF99674.1 - 3.8e-36 125.4 0.0 1.8e-35 123.2 0.0 1.8 2 0 0 2 2 2 1 Peroxidase, family 2 Lipase_GDSL_2 PF13472.6 EGF99675.1 - 0.0076 16.7 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4934 PF16288.5 EGF99676.1 - 0.019 14.8 0.1 0.028 14.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) Sld5 PF05916.11 EGF99678.1 - 1.6e-05 25.3 0.5 5.1e-05 23.7 0.5 1.8 1 1 0 1 1 1 1 GINS complex protein JAB PF01398.21 EGF99679.1 - 7.4e-32 109.8 0.0 1.4e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGF99679.1 - 2.4e-15 56.9 1.0 4e-15 56.2 1.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EGF99679.1 - 1.3e-06 28.2 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 EGF99679.1 - 0.031 14.4 0.1 0.056 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Abhydrolase_6 PF12697.7 EGF99680.1 - 8.3e-09 36.4 5.1 1e-08 36.0 5.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGF99680.1 - 5.5e-05 22.9 0.0 0.00056 19.6 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGF99680.1 - 0.00011 21.5 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EGF99680.1 - 0.0023 17.6 0.0 0.0034 17.0 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EGF99680.1 - 0.2 11.1 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Cohesin_HEAT PF12765.7 EGF99684.1 - 0.02 15.2 0.1 0.052 13.9 0.1 1.7 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Yop-YscD_cpl PF16697.5 EGF99685.1 - 0.024 14.9 0.1 0.036 14.4 0.1 1.2 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain FAM199X PF15814.5 EGF99689.1 - 0.0065 15.6 1.2 0.021 13.9 0.1 2.1 1 1 0 1 1 1 1 Protein family FAM199X UPF0560 PF10577.9 EGF99690.1 - 0.92 7.9 8.1 0.5 8.8 6.5 1.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0560 Tir_receptor_M PF03549.14 EGF99690.1 - 1.5 9.2 5.3 0.99 9.8 0.1 2.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) intimin-binding domain DUF641 PF04859.12 EGF99696.1 - 0.041 14.2 2.4 0.39 11.1 1.2 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3519 PF12033.8 EGF99696.1 - 3 8.3 7.5 4.8 7.6 3.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) SPT16 PF08644.11 EGF99696.1 - 3.9 7.6 7.9 22 5.2 1.0 3.1 3 0 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) Spc7 PF08317.11 EGF99696.1 - 6 5.7 12.1 2.5 6.9 3.8 2.6 3 0 0 3 3 3 0 Spc7 kinetochore protein IMPDH PF00478.25 EGF99697.1 - 0.0091 15.0 0.5 0.015 14.4 0.5 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Pkinase PF00069.25 EGF99698.1 - 3e-36 125.1 0.0 2.4e-19 69.7 0.0 3.0 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGF99698.1 - 7.6e-15 54.9 0.0 2.1e-12 46.9 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGF99698.1 - 0.00096 19.1 0.1 0.0071 16.3 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGF99698.1 - 0.017 14.5 0.7 0.096 12.0 0.7 2.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGF99698.1 - 0.025 13.3 0.0 0.062 12.1 0.0 1.8 1 1 1 2 2 2 0 Fungal protein kinase Ribosomal_S2 PF00318.20 EGF99699.1 - 1.1e-59 201.3 0.0 1.2e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 Citrate_synt PF00285.21 EGF99700.1 - 1.3e-123 412.7 0.0 1.5e-123 412.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Lipase_GDSL PF00657.22 EGF99701.1 - 3.9e-06 27.0 0.0 6.9e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EGF99701.1 - 0.0022 18.4 1.5 0.0061 17.0 1.5 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Thioredoxin_3 PF13192.6 EGF99701.1 - 0.16 12.0 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin domain Spc7 PF08317.11 EGF99701.1 - 0.22 10.4 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DER1 PF04511.15 EGF99702.1 - 1.2e-46 159.1 6.3 1.3e-46 158.9 6.3 1.0 1 0 0 1 1 1 1 Der1-like family F-box-like PF12937.7 EGF99703.1 - 0.0005 19.9 0.3 0.0019 18.1 0.1 2.1 2 0 0 2 2 2 1 F-box-like CSN8_PSD8_EIF3K PF10075.9 EGF99704.1 - 1.1e-25 90.3 0.1 2.9e-25 88.9 0.0 1.8 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family BING4CT PF08149.11 EGF99704.1 - 0.053 13.3 0.1 7.7 6.4 0.1 2.5 2 0 0 2 2 2 0 BING4CT (NUC141) domain eIF2A PF08662.11 EGF99705.1 - 1.1e-81 273.4 0.7 5e-79 264.7 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EGF99705.1 - 1.6e-05 25.1 0.0 0.05 13.9 0.0 4.2 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGF99705.1 - 0.0019 16.8 0.0 0.032 12.8 0.0 2.7 2 2 1 3 3 3 1 Cytochrome D1 heme domain WD40 PF00400.32 EGF99705.1 - 0.0024 18.7 1.1 13 6.9 0.0 4.8 4 1 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.6 EGF99705.1 - 0.0057 17.1 1.9 0.0057 17.1 1.9 2.3 2 0 0 2 2 2 1 Carnitine deficiency-associated protein 3 PD40 PF07676.12 EGF99705.1 - 0.2 11.6 3.8 55 3.9 0.2 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Urocanase PF01175.18 EGF99705.1 - 0.33 10.6 3.2 16 5.1 2.9 2.3 2 0 0 2 2 2 0 Urocanase Rossmann-like domain RNase_T PF00929.24 EGF99706.1 - 2.3e-26 93.3 0.1 8.1e-26 91.5 0.1 1.7 1 1 0 1 1 1 1 Exonuclease SKN1 PF03935.15 EGF99707.1 - 9.5e-168 558.7 12.1 1.1e-167 558.5 12.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) RRM_1 PF00076.22 EGF99708.1 - 1.3e-06 28.1 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VirC2 PF07181.11 EGF99708.1 - 0.015 14.7 0.3 0.033 13.6 0.3 1.5 1 0 0 1 1 1 0 VirC2 protein Btz PF09405.10 EGF99708.1 - 0.11 12.7 0.6 0.28 11.4 0.6 1.6 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Thioredoxin_6 PF13848.6 EGF99710.1 - 3.6e-06 27.0 0.0 3.6e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like domain Gal_mutarotas_2 PF13802.6 EGF99711.1 - 1.4e-05 25.3 0.6 1.7e-05 25.0 0.6 1.1 1 0 0 1 1 1 1 Galactose mutarotase-like MIF4G PF02854.19 EGF99712.1 - 4.6e-55 186.5 1.4 8e-55 185.8 1.4 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EGF99712.1 - 7.6e-22 77.3 0.0 2.8e-21 75.5 0.0 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 EGF99712.1 - 7e-08 32.4 0.6 1e-06 28.7 0.0 2.6 3 0 0 3 3 3 1 MA3 domain MIF4G PF02854.19 EGF99713.1 - 1.2e-52 178.7 1.4 1.5e-52 178.3 1.4 1.1 1 0 0 1 1 1 1 MIF4G domain Interferon PF00143.19 EGF99713.1 - 0.04 14.1 1.1 0.27 11.4 0.4 2.3 2 0 0 2 2 2 0 Interferon alpha/beta domain DUF445 PF04286.12 EGF99713.1 - 1.2 8.9 7.3 0.49 10.1 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) ERp29 PF07749.12 EGF99713.1 - 1.8 9.5 7.9 37 5.3 0.0 3.5 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain MIF4G PF02854.19 EGF99714.1 - 2.7e-24 86.0 15.1 8e-24 84.4 15.1 1.7 1 1 0 1 1 1 1 MIF4G domain SspO PF08175.12 EGF99714.1 - 6.6 7.3 7.0 18 5.9 7.0 1.8 1 0 0 1 1 1 0 Small acid-soluble spore protein O family Acyl_transf_3 PF01757.22 EGF99715.1 - 1.9e-09 37.0 37.7 3.2e-09 36.3 37.7 1.3 1 1 0 1 1 1 1 Acyltransferase family Mito_carr PF00153.27 EGF99716.1 - 4.1e-15 55.5 0.0 7.1e-07 29.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4207 PF13904.6 EGF99719.1 - 0.043 13.5 0.2 0.19 11.4 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4207) Pkinase PF00069.25 EGF99720.1 - 1.7e-22 80.0 0.0 6.1e-20 71.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF99720.1 - 3.6e-11 42.8 0.0 5.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF99720.1 - 0.0007 18.7 0.1 0.0013 17.7 0.0 1.4 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGF99720.1 - 0.0036 17.2 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGF99720.1 - 0.011 15.1 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGF99720.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 EGF99720.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-U1 PF06220.12 EGF99721.1 - 5.4e-19 67.7 1.9 8e-19 67.1 1.9 1.3 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 EGF99721.1 - 2.7 8.0 7.0 4.9 7.1 7.0 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle RIP PF00161.19 EGF99723.1 - 0.08 12.5 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosome inactivating protein CRAL_TRIO PF00650.20 EGF99728.1 - 1.8e-32 112.3 0.1 3e-32 111.5 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGF99728.1 - 1.9e-07 31.3 0.0 3.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGF99728.1 - 1.7e-06 28.1 0.0 3.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain BATS PF06968.13 EGF99729.1 - 2.2e-21 75.8 0.0 5.8e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EGF99729.1 - 1e-15 58.5 0.0 1.9e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Glyco_transf_28 PF03033.20 EGF99730.1 - 9.9e-25 87.2 0.0 1.8e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 EGF99730.1 - 9e-06 25.6 0.0 0.0033 17.3 0.0 2.5 2 0 0 2 2 2 2 GRAM domain PH PF00169.29 EGF99730.1 - 1.7e-05 25.3 0.0 5.5e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 EGF99730.1 - 5.7e-05 22.1 0.0 0.00012 21.0 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase HSP70 PF00012.20 EGF99732.1 - 1.5e-232 773.1 7.1 1.8e-232 772.8 7.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGF99732.1 - 9.1e-15 54.3 0.5 9.5e-14 50.9 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGF99732.1 - 0.00053 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1464 PF07318.12 EGF99732.1 - 0.032 13.4 0.9 0.081 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) StbA PF06406.11 EGF99732.1 - 0.048 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 StbA protein Mago_nashi PF02792.14 EGF99732.1 - 0.076 13.1 0.5 0.51 10.4 0.1 2.1 2 0 0 2 2 2 0 Mago nashi protein eIF2A PF08662.11 EGF99733.1 - 1.4e-33 116.4 0.2 1.9e-30 106.2 0.1 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EGF99733.1 - 0.0009 19.5 0.0 0.02 15.2 0.0 2.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CSN8_PSD8_EIF3K PF10075.9 EGF99735.1 - 1.9e-09 37.7 0.1 1.2e-08 35.0 0.1 1.9 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Parathyroid PF01279.17 EGF99736.1 - 0.096 13.3 0.9 4.2 8.1 0.0 3.5 1 1 2 3 3 3 0 Parathyroid hormone family Proteasome PF00227.26 EGF99740.1 - 6.1e-46 156.3 0.2 6.9e-46 156.1 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit 14-3-3 PF00244.20 EGF99741.1 - 3e-105 350.7 4.1 3.4e-105 350.5 4.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 EGF99741.1 - 0.037 14.3 0.2 9.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SPRY PF00622.28 EGF99743.1 - 8.4e-07 29.1 0.0 7.3e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 SPRY domain DUF1115 PF06544.12 EGF99744.1 - 1.7e-09 37.9 0.4 2.6e-09 37.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) HTH_19 PF12844.7 EGF99744.1 - 0.081 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_5 PF07728.14 EGF99746.1 - 1.2e-50 171.1 0.0 2.8e-23 82.5 0.0 3.5 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF99746.1 - 0.0035 17.7 0.0 18 5.7 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain VWA_2 PF13519.6 EGF99746.1 - 0.11 13.1 0.0 0.7 10.6 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain Pkinase PF00069.25 EGF99747.1 - 1.4e-42 145.9 0.0 2.3e-36 125.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF99747.1 - 2e-22 79.7 0.0 5.4e-19 68.5 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGF99747.1 - 0.0013 18.7 0.0 0.0018 18.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF99747.1 - 0.0016 17.5 0.0 0.029 13.3 0.0 2.0 1 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGF99747.1 - 0.012 14.9 0.0 0.016 14.6 0.0 1.3 1 1 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 EGF99747.1 - 0.022 13.7 0.1 0.04 12.9 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4744 PF15918.5 EGF99747.1 - 0.029 15.2 0.0 0.07 14.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) Kdo PF06293.14 EGF99747.1 - 0.088 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGF99747.1 - 0.21 10.3 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RRP7 PF12923.7 EGF99748.1 - 3.1e-15 56.3 15.7 4.8e-15 55.7 13.8 2.1 2 1 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain zf-CCHH PF10283.9 EGF99749.1 - 0.072 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 PBZ domain F-box-like PF12937.7 EGF99750.1 - 1.1e-05 25.2 0.0 2.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGF99750.1 - 0.0052 16.6 0.0 0.014 15.2 0.0 1.8 1 1 0 1 1 1 1 F-box domain TP2 PF01254.18 EGF99751.1 - 6.6 7.3 12.1 11 6.6 5.0 2.2 2 0 0 2 2 2 0 Nuclear transition protein 2 CDC24_OB3 PF17244.2 EGF99752.1 - 0.0027 17.5 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 3 POT1 PF02765.17 EGF99752.1 - 0.0041 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 EGF99752.1 - 0.018 15.0 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Replication protein A OB domain DUF2357 PF09823.9 EGF99753.1 - 0.05 12.9 0.5 0.61 9.3 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2357) DUF1161 PF06649.12 EGF99753.1 - 0.089 13.0 0.0 2.9 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1161) Smg4_UPF3 PF03467.15 EGF99754.1 - 0.021 14.8 0.3 0.027 14.5 0.3 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family PI3Ka PF00613.20 EGF99754.1 - 0.062 12.7 0.1 0.084 12.3 0.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) ATG11 PF10377.9 EGF99755.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 11 Disulph_isomer PF06491.11 EGF99756.1 - 0.12 12.5 0.2 0.16 12.1 0.2 1.2 1 0 0 1 1 1 0 Disulphide isomerase Arg_repressor_C PF02863.18 EGF99757.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Chordopox_A33R PF05966.12 EGF99760.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein zf-C2H2_aberr PF17017.5 EGF99761.1 - 2.6e-06 27.7 0.0 0.01 16.0 0.0 2.6 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 EGF99761.1 - 0.028 14.9 0.7 4.2 8.0 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF99761.1 - 0.14 13.0 3.1 11 7.1 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger DUF2981 PF11200.8 EGF99762.1 - 0.025 14.3 0.2 0.032 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) PP2C_C PF07830.13 EGF99762.1 - 0.062 13.8 0.4 0.18 12.3 0.3 1.9 1 1 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Cadherin_C_2 PF16492.5 EGF99762.1 - 0.086 13.6 0.1 0.26 12.0 0.0 1.8 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Abhydrolase_1 PF00561.20 EGF99765.1 - 1.8e-07 31.1 0.1 4.1e-07 29.9 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGF99765.1 - 5.6e-07 29.1 0.0 2e-06 27.2 0.0 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DUF3646 PF12362.8 EGF99766.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal TSC22 PF01166.18 EGF99767.1 - 0.037 14.3 9.8 0.33 11.3 1.0 3.8 2 1 2 4 4 4 0 TSC-22/dip/bun family CK2S PF15011.6 EGF99767.1 - 0.24 11.3 4.4 5.2 6.9 1.1 2.2 1 1 1 2 2 2 0 Casein Kinase 2 substrate bZIP_2 PF07716.15 EGF99767.1 - 0.55 10.4 4.8 38 4.5 0.9 3.2 2 1 1 3 3 3 0 Basic region leucine zipper CtIP_N PF10482.9 EGF99767.1 - 0.58 10.2 8.4 2.4 8.2 1.6 2.8 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain ZapB PF06005.12 EGF99767.1 - 0.73 10.3 4.6 20 5.7 0.4 3.0 1 1 1 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 EGF99767.1 - 0.85 9.8 3.0 13 6.0 0.2 2.9 2 1 1 3 3 3 0 bZIP transcription factor DUF2935 PF11155.8 EGF99767.1 - 1.2 9.4 4.5 4.6 7.6 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF16 PF01519.16 EGF99767.1 - 1.5 9.4 5.7 2.9 8.4 4.0 2.2 2 1 0 2 2 2 0 Protein of unknown function DUF16 Csm1_N PF18504.1 EGF99767.1 - 3.1 8.2 5.9 6.9 7.1 0.2 2.8 2 1 1 3 3 3 0 Csm1 N-terminal domain SDA1 PF05285.12 EGF99769.1 - 1.7 8.0 13.3 2.4 7.5 13.3 1.1 1 0 0 1 1 1 0 SDA1 PI3K_1B_p101 PF10486.9 EGF99769.1 - 6 4.5 5.7 7.8 4.1 5.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop14 PF04147.12 EGF99769.1 - 6.2 4.9 14.2 8 4.5 14.2 1.0 1 0 0 1 1 1 0 Nop14-like family Com_YlbF PF06133.11 EGF99770.1 - 0.011 16.4 0.8 1.7 9.3 0.0 2.3 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA RXLR PF16810.5 EGF99770.1 - 0.02 15.3 0.4 0.031 14.7 0.4 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity SNase PF00565.17 EGF99771.1 - 0.026 15.0 0.0 0.056 13.9 0.0 1.5 1 0 0 1 1 1 0 Staphylococcal nuclease homologue BRCA2 PF00634.18 EGF99771.1 - 0.04 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 BRCA2 repeat adh_short PF00106.25 EGF99775.1 - 1.6e-21 76.7 0.1 2.2e-16 59.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGF99775.1 - 2.4e-13 50.2 0.0 1.6e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF99775.1 - 1.4e-08 34.9 0.1 2.7e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGF99775.1 - 0.057 13.3 0.1 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding DUF4629 PF15442.6 EGF99777.1 - 0.045 14.0 8.5 0.061 13.6 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) Hydin_ADK PF17213.3 EGF99777.1 - 2.5 8.3 8.6 3.4 7.9 8.6 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Pkinase PF00069.25 EGF99778.1 - 4.3e-55 186.9 0.0 4.9e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF99778.1 - 7.6e-31 107.3 0.1 9.4e-31 107.0 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF99778.1 - 8e-06 25.4 0.0 2.1e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGF99778.1 - 0.0015 18.5 0.0 0.22 11.4 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGF99778.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGF99778.1 - 0.034 13.8 0.6 0.59 9.7 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ATP_bind_1 PF03029.17 EGF99779.1 - 8.1e-72 241.9 0.0 9.9e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein KTI12 PF08433.10 EGF99779.1 - 0.0032 17.0 0.0 0.01 15.3 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_24 PF13479.6 EGF99779.1 - 0.0086 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 EGF99779.1 - 0.017 14.9 0.0 0.043 13.6 0.0 1.8 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 EGF99779.1 - 0.017 15.6 0.1 0.065 13.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGF99779.1 - 0.018 15.2 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EGF99779.1 - 0.029 14.4 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 EGF99779.1 - 0.042 13.9 0.3 0.35 11.0 0.3 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EGF99779.1 - 0.058 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGF99779.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.29 EGF99779.1 - 0.074 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EGF99779.1 - 0.11 12.9 0.2 0.45 10.9 0.1 2.1 2 1 0 2 2 2 0 AAA domain UDPGP PF01704.18 EGF99780.1 - 2.3e-52 178.0 0.0 3.3e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EGF99780.1 - 0.058 13.8 0.0 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain MIP PF00230.20 EGF99782.1 - 1e-41 143.1 18.9 1.4e-41 142.7 18.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_47 PF01532.20 EGF99783.1 - 4.5e-81 273.1 0.3 9e-77 258.9 0.3 3.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Neugrin PF06413.11 EGF99784.1 - 0.03 14.3 1.6 0.032 14.3 1.6 1.0 1 0 0 1 1 1 0 Neugrin DUF1155 PF06633.11 EGF99785.1 - 0.032 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) MtlR PF05068.12 EGF99786.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Mannitol repressor Med9 PF07544.13 EGF99789.1 - 0.00036 20.6 2.9 0.016 15.3 0.3 2.5 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 LPP PF04728.13 EGF99789.1 - 0.0038 17.6 2.4 2.3 8.6 0.1 2.7 3 0 0 3 3 3 2 Lipoprotein leucine-zipper NPV_P10 PF05531.12 EGF99789.1 - 0.0046 17.4 6.1 0.56 10.7 0.5 2.4 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 EGF99789.1 - 0.0056 15.4 1.6 0.0073 15.0 1.6 1.1 1 0 0 1 1 1 1 AAA domain FlaC_arch PF05377.11 EGF99789.1 - 0.014 15.8 2.5 0.34 11.3 0.3 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 EGF99789.1 - 0.018 15.1 5.2 0.037 14.1 4.3 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 EGF99789.1 - 0.025 15.0 2.9 0.043 14.2 2.6 1.5 1 1 0 1 1 1 0 Snapin/Pallidin KxDL PF10241.9 EGF99789.1 - 0.031 14.6 3.1 0.21 11.9 0.5 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein Csm1_N PF18504.1 EGF99789.1 - 0.033 14.5 3.0 3.5 8.0 0.2 2.7 2 1 0 2 2 2 0 Csm1 N-terminal domain Syntaxin PF00804.25 EGF99789.1 - 0.034 13.8 3.3 0.049 13.3 2.9 1.4 1 1 0 1 1 1 0 Syntaxin SRA1 PF07304.11 EGF99789.1 - 0.035 13.9 0.2 0.046 13.5 0.2 1.2 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) DUF2703 PF10865.8 EGF99789.1 - 0.044 14.0 0.7 0.13 12.4 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) SKA1 PF07160.12 EGF99789.1 - 0.1 12.5 4.4 0.15 11.9 0.5 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 ISG65-75 PF11727.8 EGF99789.1 - 0.11 11.7 3.1 0.18 11.0 3.0 1.3 1 1 0 1 1 1 0 Invariant surface glycoprotein DUF4407 PF14362.6 EGF99789.1 - 0.12 11.7 1.9 0.25 10.7 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EGF99789.1 - 0.15 12.1 4.0 0.4 10.7 4.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EGF99789.1 - 0.21 10.4 4.3 0.29 10.0 4.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 EGF99789.1 - 0.43 10.9 6.7 4 7.8 0.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FlxA PF14282.6 EGF99789.1 - 0.56 10.2 4.3 3.1 7.8 3.7 2.0 1 1 1 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 EGF99789.1 - 0.71 10.1 3.6 12 6.1 0.2 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 EGF99789.1 - 0.81 10.0 7.1 0.83 10.0 0.5 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 EGF99789.1 - 1.5 9.1 6.1 10 6.4 1.0 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Cep57_MT_bd PF06657.13 EGF99789.1 - 1.9 9.0 6.7 22 5.6 1.1 3.0 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Rx_N PF18052.1 EGF99789.1 - 3.4 8.0 6.9 92 3.4 6.9 2.3 1 1 0 1 1 1 0 Rx N-terminal domain COG2 PF06148.11 EGF99789.1 - 8 6.6 8.3 2.3 8.3 0.4 2.5 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CxC1 PF18802.1 EGF99790.1 - 7.4e-30 103.2 0.1 1.3e-29 102.4 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGF99790.1 - 2e-26 93.0 0.0 2.9e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EGF99790.1 - 5.9e-09 36.1 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGF99790.1 - 0.074 12.9 0.2 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases Asparaginase PF00710.20 EGF99792.1 - 1.1e-48 165.4 0.0 1.8e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EGF99792.1 - 5.8e-30 103.8 0.0 9.5e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 EGF99792.1 - 4.2e-14 52.9 3.8 2.6e-08 34.3 0.7 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF99792.1 - 1.5e-11 44.5 3.2 5.9e-10 39.5 1.3 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGF99792.1 - 1.4e-08 34.8 0.3 7e-08 32.6 0.1 2.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF99792.1 - 4.8e-06 26.5 2.0 0.029 14.9 0.1 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EGF99792.1 - 2.4e-05 24.6 5.2 0.00095 19.5 0.3 3.5 3 0 0 3 3 3 2 Ankyrin repeat BRAP2 PF07576.12 EGF99793.1 - 0.042 14.1 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 ubiquitin PF00240.23 EGF99794.1 - 1.4e-17 63.1 0.2 2.4e-17 62.5 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EGF99794.1 - 2e-11 43.6 1.7 9.9e-11 41.3 0.1 2.7 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 EGF99794.1 - 1.7e-05 24.6 0.0 3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGF99794.1 - 4.9e-05 23.8 0.1 9.1e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain CUE PF02845.16 EGF99794.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 CUE domain Rad60-SLD_2 PF13881.6 EGF99794.1 - 0.0068 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Mfa1 PF17445.2 EGF99794.1 - 0.022 14.8 3.4 0.12 12.4 3.4 2.3 1 0 0 1 1 1 0 Mating factor A1 Ubiquitin_4 PF18036.1 EGF99794.1 - 0.064 13.3 0.1 1.7 8.7 0.1 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain HOIP-UBA PF16678.5 EGF99794.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair GerD PF17898.1 EGF99794.1 - 0.3 11.0 1.8 0.69 9.9 1.8 1.6 1 0 0 1 1 1 0 Spore germination GerD central core domain Cohesin_HEAT PF12765.7 EGF99794.1 - 0.31 11.4 3.7 4.1 7.8 0.1 3.8 3 1 1 4 4 4 0 HEAT repeat associated with sister chromatid cohesion STI1 PF17830.1 EGF99794.1 - 1.5 8.8 18.8 3.3 7.7 6.8 3.6 2 1 1 3 3 3 0 STI1 domain Piwi PF02171.17 EGF99795.1 - 4.2e-21 75.5 0.0 4.6e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Piwi domain DUF3157 PF11355.8 EGF99796.1 - 0.025 14.2 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) DUF3510 PF12022.8 EGF99797.1 - 5.8e-20 72.0 0.5 1.4e-19 70.7 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) UPF0122 PF04297.14 EGF99797.1 - 1 9.6 4.9 6.4 7.1 1.4 3.0 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Syntaxin_2 PF14523.6 EGF99798.1 - 0.0041 17.5 0.2 0.014 15.8 0.0 2.0 2 1 0 2 2 2 1 Syntaxin-like protein KorB PF08535.10 EGF99798.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 KorB domain Symplekin_C PF12295.8 EGF99798.1 - 0.2 11.7 0.2 0.32 11.1 0.0 1.4 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal CLTH PF10607.9 EGF99801.1 - 4e-31 107.9 0.0 8.8e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGF99801.1 - 0.0023 17.8 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 LisH SesA PF17107.5 EGF99801.1 - 0.13 12.5 0.3 0.87 9.8 0.0 2.4 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ribosomal_L31 PF01197.18 EGF99802.1 - 0.00015 22.0 0.0 0.0025 18.0 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein L31 DHHC PF01529.20 EGF99803.1 - 1.7e-33 115.6 9.3 1.7e-33 115.6 9.3 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase WIF PF02019.18 EGF99805.1 - 0.12 12.0 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 WIF domain DUF3560 PF12083.8 EGF99806.1 - 0.015 15.4 0.2 0.02 15.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) ESX-1_EspG PF14011.6 EGF99806.1 - 0.13 11.9 0.1 0.16 11.6 0.1 1.1 1 0 0 1 1 1 0 EspG family Rsm22 PF09243.10 EGF99807.1 - 8.9e-54 182.6 0.1 1.5e-45 155.6 0.0 2.4 1 1 1 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.14 EGF99807.1 - 0.0019 17.7 0.0 0.0052 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGF99807.1 - 0.013 15.3 0.0 0.06 13.2 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGF99807.1 - 0.021 15.5 0.1 0.31 11.8 0.0 2.6 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 EGF99807.1 - 1.2 9.1 3.6 8.8 6.3 3.6 2.2 1 1 0 1 1 1 0 Methyltransferase domain DHHC PF01529.20 EGF99808.1 - 1.3e-31 109.5 1.6 1.3e-31 109.5 1.6 2.3 2 0 0 2 2 2 2 DHHC palmitoyltransferase AvrM-A PF18241.1 EGF99810.1 - 5.5e-58 195.6 15.1 5.5e-58 195.6 15.1 1.8 2 0 0 2 2 2 1 Flax-rust effector AvrM-A AvrM_N PF18247.1 EGF99810.1 - 1.5e-06 28.0 0.2 2.3e-05 24.2 0.0 2.7 3 0 0 3 3 3 1 Flax-rust effector AvrM N-terminal domain CHASE8 PF17152.4 EGF99810.1 - 0.0091 16.2 0.4 0.024 14.9 0.2 1.9 2 0 0 2 2 2 1 Periplasmic sensor domain FIVAR PF07554.13 EGF99810.1 - 1.7 9.5 7.5 0.34 11.7 1.7 2.8 3 0 0 3 3 3 0 FIVAR domain AvrM-A PF18241.1 EGF99811.1 - 9.9e-37 126.6 5.0 9.9e-37 126.6 5.0 3.3 2 1 1 3 3 3 1 Flax-rust effector AvrM-A AvrM_N PF18247.1 EGF99811.1 - 5.2e-32 109.6 1.5 5.2e-32 109.6 1.5 2.6 3 0 0 3 3 3 1 Flax-rust effector AvrM N-terminal domain ETC_C1_NDUFA5 PF04716.14 EGF99811.1 - 0.035 13.9 0.2 0.26 11.1 0.0 2.5 2 0 0 2 2 2 0 ETC complex I subunit conserved region Prog_receptor PF02161.15 EGF99811.1 - 0.15 10.8 0.4 0.21 10.3 0.4 1.1 1 0 0 1 1 1 0 Progesterone receptor DUF3127 PF11325.8 EGF99811.1 - 0.43 10.8 3.1 1.1 9.5 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3127) Sin3a_C PF16879.5 EGF99814.1 - 3.3e-64 217.4 0.0 9.4e-64 215.9 0.0 1.8 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 EGF99814.1 - 4.3e-39 132.4 1.2 2.3e-15 56.4 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EGF99814.1 - 2.9e-33 113.9 0.0 7.7e-33 112.5 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor EF-hand_1 PF00036.32 EGF99815.1 - 2.3e-27 92.4 16.9 1.5e-09 36.7 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGF99815.1 - 4.7e-27 94.2 11.1 1.5e-14 54.2 3.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGF99815.1 - 4.7e-22 76.0 12.6 2.1e-08 33.4 0.1 4.6 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EGF99815.1 - 1.7e-15 56.6 13.7 1.6e-09 37.4 1.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGF99815.1 - 1.6e-13 49.5 15.4 1e-05 24.8 0.1 3.9 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EGF99815.1 - 2.2e-09 37.5 0.5 0.00044 20.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGF99815.1 - 9.5e-07 28.7 5.4 0.00068 19.6 0.1 2.6 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EGF99815.1 - 5.6e-05 23.1 1.5 0.083 12.8 0.0 3.7 1 1 3 4 4 4 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 EGF99815.1 - 0.00031 21.1 4.2 0.065 13.6 0.6 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EGF99815.1 - 0.00046 20.3 0.0 0.012 15.8 0.0 2.2 2 0 0 2 2 2 1 Dockerin type I domain DUF150 PF02576.17 EGF99815.1 - 0.026 14.9 0.2 0.063 13.7 0.2 1.9 1 1 0 1 1 1 0 RimP N-terminal domain HTH_40 PF14493.6 EGF99815.1 - 0.027 14.9 1.4 1.7 9.2 0.3 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain EF-hand_11 PF08976.11 EGF99815.1 - 0.037 14.9 0.5 0.79 10.6 0.1 2.4 2 1 1 3 3 3 0 EF-hand domain EF-hand_14 PF17959.1 EGF99815.1 - 0.18 12.2 2.8 16 5.9 0.3 2.6 1 1 2 3 3 3 0 EF-hand domain PhetRS_B1 PF18262.1 EGF99815.1 - 1.3 9.3 5.9 0.38 11.0 1.4 2.3 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain Zn_ribbon_recom PF13408.6 EGF99816.1 - 4 8.0 16.2 7.8 7.1 13.5 2.3 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain HMG_box PF00505.19 EGF99817.1 - 0.13 12.7 0.1 3.8 8.0 0.0 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box CobT PF06213.12 EGF99817.1 - 0.3 10.4 12.7 0.58 9.5 12.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF512 PF04459.12 EGF99819.1 - 0.043 13.1 0.1 0.11 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF512) YtxH PF12732.7 EGF99819.1 - 0.14 12.7 0.2 10 6.7 0.0 3.2 3 1 0 3 3 3 0 YtxH-like protein DUF4686 PF15742.5 EGF99819.1 - 0.34 10.0 15.1 0.0091 15.2 8.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) VSG_B PF13206.6 EGF99819.1 - 0.74 9.0 5.0 1.4 8.1 5.0 1.4 1 0 0 1 1 1 0 Trypanosomal VSG domain MCM2_N PF12619.8 EGF99819.1 - 0.81 10.0 7.6 0.34 11.2 2.1 2.7 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 BNIP2 PF12496.8 EGF99821.1 - 1.1 9.7 8.9 1.8 9.0 6.6 2.7 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Asp PF00026.23 EGF99822.1 - 2.6e-59 201.2 2.7 3.2e-59 200.9 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF99822.1 - 8.5e-12 45.7 0.5 3.1e-11 43.9 0.5 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Velvet PF11754.8 EGF99823.1 - 2.9e-27 96.2 0.2 2.9e-27 96.2 0.2 2.3 1 1 1 2 2 2 1 Velvet factor DUF1770 PF08589.10 EGF99823.1 - 1 10.3 4.6 3.9 8.5 4.6 2.1 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1770) GRDP-like PF07173.12 EGF99824.1 - 2.4e-11 44.4 0.0 5.3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like Aminotran_1_2 PF00155.21 EGF99825.1 - 8.4e-10 38.3 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Enolase_C PF00113.22 EGF99826.1 - 5.1e-143 475.7 0.1 7.1e-143 475.2 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGF99826.1 - 4.5e-59 198.3 0.3 8e-59 197.5 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGF99826.1 - 4e-09 36.3 0.0 8.6e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EGF99826.1 - 0.003 16.8 1.9 0.0042 16.3 0.3 2.0 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Glyco_hydro_47 PF01532.20 EGF99828.1 - 2.2e-122 409.3 0.0 3.2e-122 408.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Na_Ca_ex PF01699.24 EGF99829.1 - 6.2e-21 74.9 20.1 1.1e-20 74.1 20.1 1.4 1 0 0 1 1 1 1 Sodium/calcium exchanger protein UPF0203 PF05254.12 EGF99830.1 - 2.3e-25 88.6 1.2 2.7e-25 88.4 1.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 EGF99830.1 - 0.00055 20.1 0.1 0.0008 19.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.9 EGF99830.1 - 0.091 13.1 0.8 6.1 7.2 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EGF99830.1 - 0.14 12.2 1.4 0.33 11.0 0.3 2.0 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GRDP-like PF07173.12 EGF99833.1 - 7.6e-24 85.0 1.7 2.7e-14 54.0 0.0 3.3 2 1 1 3 3 3 3 Glycine-rich domain-containing protein-like Corazonin PF17308.2 EGF99833.1 - 0.015 15.7 1.2 1.8 8.9 0.0 3.2 4 0 0 4 4 4 0 Pro-corazonin PhnA_Zn_Ribbon PF08274.12 EGF99833.1 - 0.84 9.6 4.8 3 7.9 4.8 2.0 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Metallophos_2 PF12850.7 EGF99834.1 - 5.3e-13 49.5 0.0 8.4e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_12 PF01670.16 EGF99835.1 - 3.6e-14 53.3 0.6 5.6e-14 52.7 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_hydro_12 PF01670.16 EGF99836.1 - 7.2e-14 52.3 0.6 1e-13 51.8 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 ANAPC4_WD40 PF12894.7 EGF99837.1 - 3.9e-05 23.9 0.0 0.0098 16.2 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGF99837.1 - 0.063 14.2 0.8 45 5.1 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat CNH PF00780.22 EGF99837.1 - 0.16 11.5 0.1 0.87 9.1 0.0 2.2 2 0 0 2 2 2 0 CNH domain FTP PF07504.13 EGF99838.1 - 0.2 11.5 6.2 0.43 10.4 0.0 4.0 5 0 0 5 5 5 0 Fungalysin/Thermolysin Propeptide Motif DnaJ PF00226.31 EGF99840.1 - 1.3e-22 79.6 0.1 4.8e-22 77.9 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 EGF99840.1 - 3.2e-18 65.9 4.8 2.6e-17 63.0 4.8 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1977) PAP2 PF01569.21 EGF99841.1 - 1.1e-17 64.0 6.4 1.1e-17 64.0 4.2 2.2 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EGF99841.1 - 0.0018 18.0 1.2 0.0051 16.5 1.2 1.8 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 EGF99841.1 - 0.14 12.3 1.0 0.95 9.6 0.1 2.7 2 0 0 2 2 2 0 Divergent PAP2 family FAM60A PF15396.6 EGF99841.1 - 2.9 7.9 8.5 0.5 10.3 0.5 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Endostatin PF06482.11 EGF99841.1 - 6 6.2 9.5 9.6 5.6 0.4 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Ribosomal_S26e PF01283.19 EGF99842.1 - 4.3e-54 181.5 7.7 5.1e-54 181.3 7.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EGF99842.1 - 0.042 13.8 1.0 0.059 13.3 0.0 1.8 3 0 0 3 3 3 0 Zinc binding domain Ferritin_2 PF13668.6 EGF99843.1 - 6.9e-19 68.4 0.0 1.2e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Ras PF00071.22 EGF99845.1 - 8.3e-15 54.8 0.1 1.1e-14 54.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF99845.1 - 2.2e-07 31.1 0.1 2.8e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF1507 PF07408.11 EGF99845.1 - 0.11 12.4 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) Glyco_hydro_16 PF00722.21 EGF99846.1 - 7.8e-08 32.0 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 EphA2_TM PF14575.6 EGF99847.1 - 0.049 14.5 0.0 0.28 12.1 0.0 2.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 EGF99847.1 - 0.58 8.8 0.0 0.58 8.8 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF5442 PF17514.2 EGF99850.1 - 0.0079 16.4 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5442) Ribosomal_L2_C PF03947.18 EGF99851.1 - 3.5e-46 156.5 4.3 6.4e-46 155.6 4.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGF99851.1 - 1.4e-13 50.6 0.0 4.2e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF2126 PF09899.9 EGF99852.1 - 0.057 11.5 0.1 0.073 11.1 0.1 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Actin PF00022.19 EGF99854.1 - 5.4e-151 502.8 0.0 2.3e-150 500.8 0.0 1.7 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 EGF99854.1 - 0.055 12.0 0.0 0.08 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Fungal_trans PF04082.18 EGF99855.1 - 2.6e-28 98.8 1.6 2.6e-28 98.8 1.6 2.9 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGF99855.1 - 2.3e-07 30.8 11.3 5e-07 29.7 11.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 EGF99855.1 - 5.2 6.6 29.8 13 5.3 29.8 1.6 1 0 0 1 1 1 0 Spt20 family EPL1 PF10513.9 EGF99855.1 - 7.4 6.9 12.3 0.11 12.9 3.9 2.4 3 0 0 3 3 3 0 Enhancer of polycomb-like PNP_UDP_1 PF01048.20 EGF99858.1 - 8.2e-37 126.7 0.0 9.6e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Peptidase_S64 PF08192.11 EGF99858.1 - 0.056 11.9 0.0 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 adh_short_C2 PF13561.6 EGF99859.1 - 2.8e-61 207.0 0.0 3.6e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGF99859.1 - 1.2e-46 158.7 0.1 1.5e-46 158.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGF99859.1 - 1e-06 28.8 0.1 1.7e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EGF99859.1 - 0.023 14.6 0.2 0.043 13.7 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SWIM PF04434.17 EGF99861.1 - 1.1e-07 31.4 15.8 0.0026 17.4 0.6 3.6 3 0 0 3 3 3 3 SWIM zinc finger MULE PF10551.9 EGF99861.1 - 1.3e-05 25.6 0.0 3.5e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain XRN_N PF03159.18 EGF99864.1 - 8.8e-97 323.3 0.0 1.1e-96 322.9 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 EGF99864.1 - 5.2e-05 23.1 5.7 8.7e-05 22.4 5.7 1.4 1 0 0 1 1 1 1 Zinc knuckle Muted PF14942.6 EGF99866.1 - 0.38 11.1 2.6 0.67 10.3 2.6 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein GIDE PF12483.8 EGF99867.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 E3 Ubiquitin ligase Inhibitor_I9 PF05922.16 EGF99870.1 - 0.0045 17.6 0.0 0.0045 17.6 0.0 2.8 4 1 0 4 4 4 1 Peptidase inhibitor I9 Egh16-like PF11327.8 EGF99871.1 - 7.8e-49 166.6 2.0 7.8e-49 166.6 2.0 3.1 3 1 0 3 3 3 1 Egh16-like virulence factor Col_cuticle_N PF01484.17 EGF99872.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Gemini_AL1_M PF08283.11 EGF99873.1 - 0.004 17.2 0.1 0.0075 16.3 0.1 1.4 1 0 0 1 1 1 1 Geminivirus rep protein central domain CDK2AP PF09806.9 EGF99873.1 - 0.0053 16.8 3.5 0.0087 16.1 3.5 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein PXA PF02194.15 EGF99878.1 - 9.6e-08 32.2 4.7 2.6e-06 27.6 1.8 3.0 2 1 0 2 2 2 1 PXA domain DUF676 PF05057.14 EGF99880.1 - 4.8e-11 42.6 1.2 7.8e-11 41.9 0.0 1.9 3 0 0 3 3 3 1 Putative serine esterase (DUF676) DUF3685 PF12452.8 EGF99882.1 - 0.12 12.0 1.7 0.18 11.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) Wbp11 PF09429.10 EGF99883.1 - 1.8e-17 63.5 15.4 1.8e-17 63.5 15.4 1.9 2 0 0 2 2 2 1 WW domain binding protein 11 NpwBP PF12622.7 EGF99883.1 - 4.8e-09 36.8 24.7 4.8e-09 36.8 24.7 4.8 4 3 0 4 4 4 1 mRNA biogenesis factor Astro_capsid_p PF12226.8 EGF99883.1 - 0.063 12.4 6.7 0.11 11.6 6.7 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 EGF99883.1 - 0.14 10.3 15.6 0.24 9.5 15.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi 4HB_MCP_1 PF12729.7 EGF99883.1 - 0.38 10.3 3.7 0.58 9.7 3.7 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF5304 PF17230.2 EGF99883.1 - 1.8 8.8 0.0 1.8 8.8 0.0 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5304) S10_plectin PF03501.15 EGF99884.1 - 1.1e-43 147.2 0.2 1.3e-43 146.9 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF4364 PF14277.6 EGF99884.1 - 0.17 11.6 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) RNase_PH PF01138.21 EGF99885.1 - 1.8e-11 44.6 0.2 2e-09 38.1 0.2 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Coa1 PF08695.10 EGF99886.1 - 1e-23 83.3 0.0 1.8e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Acyl-CoA_dh_1 PF00441.24 EGF99887.1 - 4.5e-34 117.8 0.4 6.5e-34 117.3 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EGF99887.1 - 1.1e-17 63.9 0.1 3.1e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 EGF99887.1 - 4.3e-15 55.7 0.0 8.7e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGF99887.1 - 4.3e-14 53.1 0.2 1.6e-13 51.3 0.0 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGF99887.1 - 3.1e-07 30.7 0.1 6.2e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain WD40 PF00400.32 EGF99888.1 - 3.8e-07 30.7 3.4 0.34 11.9 0.1 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 EGF99888.1 - 0.0035 16.1 1.1 0.52 8.9 0.2 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytomega_UL84 PF06284.11 EGF99888.1 - 0.17 10.3 2.1 0.26 9.7 2.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DRMBL PF07522.14 EGF99889.1 - 3.8e-32 110.7 0.0 6.4e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EGF99889.1 - 6e-07 29.2 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zf-C2H2_12 PF18658.1 EGF99889.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type RNF220 PF15926.5 EGF99889.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 DUF1856 PF08983.10 EGF99889.1 - 0.36 11.1 2.7 0.82 9.9 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1856) URO-D PF01208.17 EGF99890.1 - 9.4e-112 373.6 0.0 1.1e-111 373.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Osmo_CC PF08946.10 EGF99890.1 - 0.13 12.5 0.8 0.28 11.5 0.8 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Ribonuclease_3 PF00636.26 EGF99893.1 - 0.00078 20.0 0.4 4.2 8.1 0.0 3.6 2 2 0 3 3 3 2 Ribonuclease III domain DUF5341 PF17276.2 EGF99894.1 - 0.018 15.2 0.2 0.021 15.0 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5341) CHDNT PF08073.12 EGF99894.1 - 0.12 12.3 0.6 0.52 10.3 0.6 2.0 1 1 0 1 1 1 0 CHDNT (NUC034) domain RasGEF PF00617.19 EGF99895.1 - 9e-60 201.9 0.3 1.6e-59 201.1 0.3 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGF99895.1 - 3.7e-23 81.7 1.6 6.1e-23 81.1 0.1 2.1 3 0 0 3 3 3 1 RasGEF N-terminal motif Svf1_C PF17187.4 EGF99896.1 - 0.057 13.2 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Svf1-like C-terminal lipocalin-like domain zf-U1 PF06220.12 EGF99897.1 - 6.9e-10 38.5 2.4 1.1e-09 37.8 2.4 1.4 1 0 0 1 1 1 1 U1 zinc finger CSRNP_N PF16019.5 EGF99898.1 - 0.048 13.6 2.8 0.065 13.2 2.8 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus ORC6 PF05460.13 EGF99898.1 - 0.14 11.4 7.0 0.15 11.3 7.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Egh16-like PF11327.8 EGF99900.1 - 2.5e-46 158.4 0.9 2.5e-46 158.4 0.9 1.7 2 0 0 2 2 2 1 Egh16-like virulence factor Mito_carr PF00153.27 EGF99901.1 - 3.6e-56 187.1 0.5 3.8e-18 65.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_47 PF01532.20 EGF99902.1 - 6.5e-122 407.7 0.4 7.6e-122 407.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CBFD_NFYB_HMF PF00808.23 EGF99903.1 - 6.6e-19 68.0 1.8 7.5e-19 67.8 1.8 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGF99903.1 - 3.4e-11 43.6 0.4 3.6e-11 43.5 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 EGF99903.1 - 0.00024 21.2 0.2 0.00027 21.0 0.2 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CENP-X PF09415.10 EGF99903.1 - 0.0011 19.3 0.1 0.0012 19.1 0.1 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TFIID-18kDa PF02269.16 EGF99903.1 - 0.012 15.7 0.4 0.022 14.7 0.4 1.5 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TAF PF02969.17 EGF99903.1 - 0.014 15.6 0.3 0.02 15.0 0.3 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Vps4_C PF09336.10 EGF99903.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 Vps4 C terminal oligomerisation domain Egh16-like PF11327.8 EGF99905.1 - 2.3e-44 152.0 1.4 2.3e-44 152.0 1.4 2.5 2 1 0 2 2 2 1 Egh16-like virulence factor HhH-GPD PF00730.25 EGF99906.1 - 1.8e-05 25.1 0.0 2.2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGF99906.1 - 0.00049 19.8 0.0 0.00082 19.1 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 EGF99906.1 - 0.042 14.2 0.5 0.042 14.2 0.5 1.7 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III DUF4054 PF13262.6 EGF99906.1 - 0.075 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) PPR_2 PF13041.6 EGF99907.1 - 1.5e-30 105.1 8.4 3.3e-12 46.4 0.1 10.0 8 2 3 11 11 11 7 PPR repeat family PPR PF01535.20 EGF99907.1 - 5.8e-26 88.9 8.6 2.6e-06 27.3 0.1 10.7 11 0 0 11 11 11 4 PPR repeat PPR_1 PF12854.7 EGF99907.1 - 3e-17 62.0 7.1 9.4e-07 28.4 0.1 6.9 7 0 0 7 7 7 3 PPR repeat PPR_3 PF13812.6 EGF99907.1 - 2e-11 43.8 0.9 5.8e-05 23.1 0.1 6.0 4 1 2 6 6 6 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EGF99907.1 - 9.6e-10 38.2 0.5 1.8e-07 30.7 0.1 3.8 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EGF99907.1 - 2.9e-05 24.5 2.2 5 8.2 0.0 7.5 9 0 0 9 9 8 1 Tetratricopeptide repeat RPM2 PF08579.11 EGF99907.1 - 0.00012 22.5 1.0 0.38 11.2 0.0 3.8 3 0 0 3 3 3 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.6 EGF99907.1 - 0.00012 22.5 0.7 19 5.9 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4423 PF14394.6 EGF99907.1 - 0.00021 21.0 0.1 0.00053 19.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) TPR_6 PF13174.6 EGF99907.1 - 0.0053 17.3 0.1 1.5 9.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGF99907.1 - 0.049 14.3 0.0 2.6 8.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SH3_1 PF00018.28 EGF99908.1 - 3.9e-07 29.6 0.0 7.9e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGF99908.1 - 0.0049 16.7 0.2 0.092 12.6 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain PolyA_pol PF01743.20 EGF99908.1 - 0.13 12.7 0.3 0.31 11.5 0.3 1.6 1 0 0 1 1 1 0 Poly A polymerase head domain RNase_PH PF01138.21 EGF99909.1 - 2.2e-23 83.2 0.2 3e-23 82.8 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF2583 PF10762.9 EGF99912.1 - 0.15 12.5 0.2 0.46 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) tRNA-synt_1b PF00579.25 EGF99913.1 - 2.3e-69 233.9 0.0 3.4e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MazG PF03819.17 EGF99913.1 - 0.16 12.2 0.3 22 5.3 0.0 2.5 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain S36_mt PF10937.8 EGF99914.1 - 1.9e-07 32.7 3.2 4.5e-07 31.4 3.2 1.5 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial ACBP PF00887.19 EGF99915.1 - 2.7e-22 78.8 0.0 3.9e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein RRM_1 PF00076.22 EGF99917.1 - 8.5e-44 147.2 0.0 8.7e-22 76.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF99917.1 - 2.2e-07 30.9 0.0 0.014 15.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EGF99917.1 - 0.024 14.6 0.0 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MAT1 PF06391.13 EGF99918.1 - 4.6e-40 137.6 19.9 5.3e-40 137.4 19.9 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EGF99918.1 - 4.4e-22 77.7 7.4 7.6e-22 77.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF99918.1 - 2.8e-06 27.1 7.5 5.4e-06 26.2 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF99918.1 - 3.4e-05 24.1 7.3 5.3e-05 23.5 7.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF99918.1 - 4.1e-05 23.3 8.1 6.8e-05 22.6 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF99918.1 - 0.00012 22.0 4.3 0.00028 20.8 4.3 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGF99918.1 - 0.01 15.9 8.2 0.021 14.9 8.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger PRORP PF16953.5 EGF99918.1 - 0.011 15.3 0.3 0.014 15.0 0.3 1.1 1 0 0 1 1 1 0 Protein-only RNase P zf-RING_4 PF14570.6 EGF99918.1 - 0.013 15.3 6.5 0.027 14.3 6.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EGF99918.1 - 0.15 12.0 7.5 1.8 8.5 7.5 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGF99918.1 - 0.54 10.6 3.7 1.3 9.4 3.7 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain DUF3797 PF12677.7 EGF99918.1 - 0.59 10.1 4.3 0.37 10.7 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-C3HC4_4 PF15227.6 EGF99918.1 - 1.7 8.9 8.4 5.7 7.2 8.4 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING CDC37_N PF03234.14 EGF99918.1 - 8.6 7.3 10.4 6.5 7.7 3.9 2.3 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Med10 PF09748.9 EGF99920.1 - 1.2e-27 96.2 0.0 1.5e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 EGF99920.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) UPF0047 PF01894.17 EGF99921.1 - 5.5e-10 39.4 0.2 8.4e-10 38.8 0.2 1.3 1 1 0 1 1 1 1 Uncharacterised protein family UPF0047 HNH PF01844.23 EGF99921.1 - 0.15 12.2 4.4 0.63 10.3 1.1 2.2 2 0 0 2 2 2 0 HNH endonuclease Med26 PF08711.11 EGF99923.1 - 0.004 17.2 0.3 0.0086 16.1 0.3 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF4407 PF14362.6 EGF99925.1 - 0.0028 17.1 1.0 0.0033 16.8 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CENP-Q PF13094.6 EGF99925.1 - 0.0029 17.9 1.0 0.0038 17.4 1.0 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Mei5 PF10376.9 EGF99925.1 - 0.0037 17.2 3.4 0.0051 16.7 3.4 1.2 1 0 0 1 1 1 1 Double-strand recombination repair protein DUF812 PF05667.11 EGF99925.1 - 0.0038 16.2 2.3 0.0049 15.8 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ADIP PF11559.8 EGF99925.1 - 0.016 15.3 1.3 0.026 14.6 1.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 EGF99925.1 - 0.06 13.6 5.0 0.1 12.9 5.0 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain DivIC PF04977.15 EGF99925.1 - 0.52 10.1 2.9 0.91 9.3 2.9 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4337 PF14235.6 EGF99925.1 - 0.94 9.6 6.0 1.6 8.8 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Vfa1 PF08432.10 EGF99925.1 - 0.98 9.7 16.3 1.5 9.1 16.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GPS2_interact PF15784.5 EGF99925.1 - 1.7 9.1 11.6 4.1 7.9 11.5 1.8 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain MscS_porin PF12795.7 EGF99925.1 - 1.9 8.0 5.4 2.9 7.4 5.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Ax_dynein_light PF10211.9 EGF99925.1 - 3.9 7.4 6.5 5.4 6.9 6.5 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain PPP4R2 PF09184.11 EGF99925.1 - 5.2 6.6 18.2 6.7 6.2 18.2 1.2 1 0 0 1 1 1 0 PPP4R2 DASH_Spc19 PF08287.11 EGF99925.1 - 7.4 6.4 10.0 3.8 7.4 7.9 1.6 1 1 0 1 1 1 0 Spc19 Hamartin PF04388.12 EGF99925.1 - 9.4 4.8 13.5 11 4.6 13.5 1.2 1 0 0 1 1 1 0 Hamartin protein DUF4207 PF13904.6 EGF99927.1 - 0.15 11.7 8.8 0.15 11.7 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) SF-assemblin PF06705.11 EGF99931.1 - 0.00078 18.9 6.9 0.0013 18.1 4.2 2.2 2 1 0 2 2 2 1 SF-assemblin/beta giardin Baculo_PEP_C PF04513.12 EGF99931.1 - 0.001 19.1 1.7 0.0013 18.8 0.4 1.8 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Mer2 PF09074.10 EGF99931.1 - 0.015 15.1 4.8 0.019 14.8 3.4 1.7 2 0 0 2 2 2 0 Mer2 Apolipoprotein PF01442.18 EGF99931.1 - 0.017 15.0 0.7 0.037 13.9 0.7 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4618 PF15397.6 EGF99931.1 - 0.02 14.3 2.3 0.033 13.6 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) ApoLp-III PF07464.11 EGF99931.1 - 0.025 14.7 2.5 0.39 10.8 0.7 2.6 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Focal_AT PF03623.13 EGF99931.1 - 0.027 14.5 1.9 0.45 10.5 0.9 2.5 2 1 0 2 2 2 0 Focal adhesion targeting region DUF1664 PF07889.12 EGF99931.1 - 0.03 14.4 2.8 0.069 13.2 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HIT PF01230.23 EGF99931.1 - 0.093 13.5 2.1 6.1 7.7 0.3 2.3 2 0 0 2 2 2 0 HIT domain CSN5_C PF18323.1 EGF99931.1 - 0.096 13.6 1.9 1.5 9.8 1.9 2.7 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF2452 PF10504.9 EGF99931.1 - 0.2 11.1 1.1 0.37 10.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) DUF1840 PF08895.11 EGF99931.1 - 0.2 12.0 2.5 13 6.1 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) DUF883 PF05957.13 EGF99931.1 - 0.24 12.0 4.4 1.1 9.9 0.1 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Syntaxin_2 PF14523.6 EGF99931.1 - 0.59 10.5 2.7 1.1 9.6 0.7 2.3 2 1 0 2 2 2 0 Syntaxin-like protein Fzo_mitofusin PF04799.13 EGF99931.1 - 0.63 9.6 2.6 1.1 8.8 1.6 1.8 2 0 0 2 2 2 0 fzo-like conserved region NPV_P10 PF05531.12 EGF99931.1 - 2.8 8.5 5.2 76 3.9 5.2 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FeThRed_B PF02943.15 EGF99934.1 - 0.044 13.8 2.5 0.099 12.7 2.5 1.5 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain DUF4769 PF15992.5 EGF99934.1 - 0.19 11.5 6.3 0.52 10.1 6.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) RRM_1 PF00076.22 EGF99935.1 - 3.9e-09 36.2 0.0 5.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAR1 PF03101.15 EGF99936.1 - 0.13 13.0 0.2 0.22 12.2 0.2 1.3 1 0 0 1 1 1 0 FAR1 DNA-binding domain Dpoe2NT PF12213.8 EGF99942.1 - 0.012 15.9 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal PAP_assoc PF03828.19 EGF99944.1 - 5.7e-17 61.7 0.0 1.5e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGF99944.1 - 5.2e-07 29.9 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EGF99944.1 - 0.059 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Lsr2 PF11774.8 EGF99949.1 - 0.031 14.4 2.1 0.095 12.8 2.1 1.8 1 0 0 1 1 1 0 Lsr2 Pkinase PF00069.25 EGF99951.1 - 1.9e-63 214.3 0.0 2.2e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF99951.1 - 2.6e-43 148.2 0.0 2.9e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGF99951.1 - 0.00051 20.0 0.0 0.0021 18.1 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGF99951.1 - 0.0009 18.1 0.0 0.005 15.7 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGF99951.1 - 0.048 13.0 0.0 3.3 6.9 0.0 2.4 3 0 0 3 3 3 0 Kinase-like RasGAP PF00616.19 EGF99952.1 - 8.7e-48 162.8 0.1 1.9e-47 161.7 0.1 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGF99952.1 - 2.1e-43 147.7 3.8 2.1e-43 147.7 3.8 2.7 3 0 0 3 3 3 1 RasGAP C-terminus IQ PF00612.27 EGF99952.1 - 7.5e-15 53.3 42.8 0.0058 16.3 0.0 12.2 12 0 0 12 12 12 7 IQ calmodulin-binding motif CH PF00307.31 EGF99952.1 - 3.4e-12 46.5 0.0 9.9e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain NUDIX PF00293.28 EGF99953.1 - 9.5e-08 32.2 0.1 1.2e-07 31.8 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain LRR_4 PF12799.7 EGF99955.1 - 0.028 14.8 5.4 51 4.5 0.2 5.7 6 1 2 8 8 8 0 Leucine Rich repeats (2 copies) RP-C_C PF11800.8 EGF99956.1 - 9.8 6.2 7.1 1 9.4 0.3 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region Aurora-A_bind PF09041.10 EGF99957.1 - 0.05 13.7 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Aurora-A binding 2H-phosphodiest PF08975.10 EGF99958.1 - 0.068 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) DUF543 PF04418.12 EGF99960.1 - 3.1e-27 94.4 0.3 3.7e-27 94.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF4407 PF14362.6 EGF99965.1 - 0.23 10.8 0.1 0.35 10.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 EGF99966.1 - 0.14 12.4 1.6 0.25 11.6 1.6 1.4 1 0 0 1 1 1 0 Haemolysin XhlA FOXP-CC PF16159.5 EGF99966.1 - 0.26 12.0 0.6 0.4 11.3 0.6 1.3 1 0 0 1 1 1 0 FOXP coiled-coil domain Sugarporin_N PF11471.8 EGF99967.1 - 0.0033 17.3 0.2 0.0033 17.3 0.2 1.9 2 0 0 2 2 2 1 Maltoporin periplasmic N-terminal extension Deltaretro_Tax PF05599.11 EGF99967.1 - 0.092 13.3 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Deltaretrovirus Tax protein XhlA PF10779.9 EGF99967.1 - 0.3 11.3 2.2 0.47 10.7 2.2 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Macoilin PF09726.9 EGF99967.1 - 0.72 8.3 5.3 0.76 8.3 5.3 1.2 1 0 0 1 1 1 0 Macoilin family Spore_coat_CotO PF14153.6 EGF99969.1 - 1.9 8.4 17.5 0.069 13.1 3.3 2.6 2 1 0 2 2 2 0 Spore coat protein CotO DUF3630 PF12305.8 EGF99970.1 - 0.032 14.3 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) TFIIA PF03153.13 EGF99970.1 - 0.6 10.0 38.0 0.028 14.4 26.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_18 PF00704.28 EGF99973.1 - 2.2e-54 185.3 1.3 2.6e-54 185.1 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 EGF99973.1 - 0.045 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 PMC2NT PF08066.12 EGF99975.1 - 0.091 13.5 0.0 0.33 11.7 0.0 2.0 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Retrotran_gag_2 PF14223.6 EGF99978.1 - 1e-06 28.5 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGF99978.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF5601 PF18151.1 EGF99978.1 - 0.33 11.3 2.3 1.2 9.5 0.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5601) Pkinase PF00069.25 EGF99979.1 - 5.6e-14 52.1 0.0 6.5e-07 29.0 0.1 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF99979.1 - 6.6e-07 28.9 0.0 0.022 14.0 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase NTP_transferase PF00483.23 EGF99983.1 - 2.4e-52 178.0 0.0 3.7e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EGF99983.1 - 1.2e-10 42.0 0.0 1.8e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EGF99983.1 - 2.2e-07 30.3 7.7 1.1e-05 24.9 0.8 3.5 2 2 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGF99983.1 - 0.00073 19.2 3.6 0.24 11.2 0.3 3.6 4 1 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 EGF99983.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SRP54 PF00448.22 EGF99983.1 - 0.017 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF4954 PF16314.5 EGF99983.1 - 0.021 13.0 0.0 0.031 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 EGF99983.1 - 0.041 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Alpha_kinase PF02816.18 EGF99984.1 - 3e-34 118.7 0.4 3.6e-34 118.5 0.4 1.1 1 0 0 1 1 1 1 Alpha-kinase family Kinetochor_Ybp2 PF08568.10 EGF99985.1 - 9.8e-15 54.1 4.0 4.9e-09 35.3 0.1 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin FTH PF01827.27 EGF99987.1 - 0.013 15.3 0.5 0.043 13.6 0.3 1.9 1 1 0 1 1 1 0 FTH domain Not3 PF04065.15 EGF99988.1 - 1.6e-86 289.5 20.5 2.8e-86 288.7 17.7 2.0 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EGF99988.1 - 4.6e-39 133.5 8.6 1.5e-38 131.8 8.6 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF1192 PF06698.11 EGF99988.1 - 0.024 14.7 0.1 0.12 12.5 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) UCH PF00443.29 EGF99990.1 - 6.9e-42 143.7 1.7 1.8e-41 142.4 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGF99990.1 - 4.3e-07 29.8 1.8 4.3e-07 29.8 1.8 3.5 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Surface_Ag_2 PF01617.17 EGF99991.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Surface antigen Mo25 PF08569.11 EGF99993.1 - 8.1e-17 61.6 1.7 9.7e-17 61.3 1.7 1.3 1 0 0 1 1 1 1 Mo25-like VPS28 PF03997.12 EGF99993.1 - 0.0096 15.6 0.2 0.023 14.4 0.0 1.7 1 1 1 2 2 2 1 VPS28 protein Asp_Glu_race_2 PF14669.6 EGF99993.1 - 0.057 13.1 0.0 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative aspartate racemase TUDOR PF00567.24 EGF99994.1 - 0.045 13.8 0.1 0.052 13.6 0.1 1.1 1 0 0 1 1 1 0 Tudor domain RsmJ PF04378.13 EGF99996.1 - 0.045 13.0 0.0 0.17 11.1 0.0 1.7 1 1 1 2 2 2 0 Ribosomal RNA large subunit methyltransferase D, RlmJ Chromo PF00385.24 EGF99997.1 - 7.5e-10 38.6 0.5 2.4e-09 36.9 0.5 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CDC27 PF09507.10 EGF99997.1 - 0.0032 16.9 16.3 0.0032 16.9 16.3 2.2 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 NOA36 PF06524.12 EGF99997.1 - 9.3 5.5 12.5 21 4.3 12.5 1.5 1 0 0 1 1 1 0 NOA36 protein AAA PF00004.29 EGF99998.1 - 4.7e-07 30.3 1.3 1.2e-05 25.8 0.4 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGF99998.1 - 0.00019 21.4 1.5 0.023 14.6 0.0 3.3 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 EGF99998.1 - 0.0097 16.3 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGF99998.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGF99998.1 - 0.019 15.3 0.3 0.087 13.1 0.3 2.1 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGF99998.1 - 0.019 14.0 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IPT PF01745.16 EGF99998.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase PI-PLC-X PF00388.19 EGG00001.1 - 1.6e-55 186.7 0.0 3e-55 185.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGG00001.1 - 6.9e-37 126.3 0.0 2e-36 124.8 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGG00001.1 - 2.1e-13 50.4 0.0 5.3e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 EGG00001.1 - 8.2e-06 26.2 0.0 2.5e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.6 EGG00001.1 - 9e-06 26.1 2.5 0.0057 17.1 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 EGG00001.1 - 0.0062 16.4 0.2 0.013 15.3 0.2 1.6 1 0 0 1 1 1 1 EF hand GDPD PF03009.17 EGG00001.1 - 0.012 15.4 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family EF-hand_6 PF13405.6 EGG00001.1 - 0.012 15.4 0.5 1.5 8.9 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain MltA PF03562.17 EGG00003.1 - 0.044 13.5 0.1 0.046 13.5 0.1 1.1 1 0 0 1 1 1 0 MltA specific insert domain BRO1 PF03097.18 EGG00004.1 - 1.2e-106 356.8 0.2 1.7e-106 356.3 0.2 1.2 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EGG00004.1 - 5.8e-66 222.8 7.1 1.1e-65 221.9 7.1 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV MPM1 PF17234.2 EGG00004.1 - 0.048 13.9 2.7 0.1 12.8 2.7 1.5 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 ATP_sub_h PF10775.9 EGG00006.1 - 2.4e-20 72.3 0.5 3.3e-20 71.8 0.5 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h Podoplanin PF05808.11 EGG00007.1 - 1.3 9.1 8.0 7.9 6.6 0.1 2.8 2 1 0 2 2 2 0 Podoplanin F-box-like PF12937.7 EGG00009.1 - 0.00041 20.2 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG00009.1 - 0.023 14.6 0.1 0.072 13.0 0.0 1.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 EGG00011.1 - 0.042 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like Ribosomal_L11_N PF03946.14 EGG00014.1 - 0.013 15.4 0.1 0.48 10.3 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain SSB PF00436.25 EGG00017.1 - 0.098 12.7 0.1 0.39 10.8 0.1 1.8 1 1 1 2 2 2 0 Single-strand binding protein family NTP_transferase PF00483.23 EGG00018.1 - 1.4e-52 178.7 0.0 2e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EGG00018.1 - 7.2e-11 42.7 0.0 1.1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EGG00018.1 - 1.2e-10 40.7 15.6 4.8e-06 26.1 1.9 3.9 1 1 4 5 5 5 4 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EGG00018.1 - 0.0023 16.2 0.1 0.0033 15.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 EGG00018.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SRP54 PF00448.22 EGG00018.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CTP_transf_3 PF02348.19 EGG00018.1 - 0.043 13.7 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase DUF1541 PF07563.11 EGG00018.1 - 0.49 10.3 3.0 53 3.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) Hexapep_2 PF14602.6 EGG00018.1 - 0.97 9.2 5.7 0.82 9.5 0.2 3.5 5 0 0 5 5 5 0 Hexapeptide repeat of succinyl-transferase Ras PF00071.22 EGG00019.1 - 4.5e-44 149.9 0.0 5.3e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG00019.1 - 3.9e-13 49.7 0.0 5.3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG00019.1 - 0.00014 21.4 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG00019.1 - 0.00018 21.1 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG00019.1 - 0.0014 18.7 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG00019.1 - 0.0027 17.6 0.1 0.28 11.1 0.0 2.1 1 1 1 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 EGG00019.1 - 0.0095 16.0 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 EGG00019.1 - 0.083 12.3 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGG00019.1 - 0.093 13.1 0.0 0.15 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF4477 PF14780.6 EGG00020.1 - 0.00061 19.5 3.0 0.012 15.3 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4477) Fe-ADH PF00465.19 EGG00021.1 - 3.1e-10 39.4 2.2 9.8e-07 27.9 0.6 2.0 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase FAR1 PF03101.15 EGG00024.1 - 7.7e-05 23.3 0.5 7.7e-05 23.3 0.5 2.3 3 0 0 3 3 3 1 FAR1 DNA-binding domain AFT PF08731.11 EGG00024.1 - 0.014 15.8 0.6 0.014 15.8 0.6 2.5 2 2 0 2 2 2 0 Transcription factor AFT CLZ PF16526.5 EGG00026.1 - 0.0016 18.7 4.0 0.31 11.4 0.1 2.5 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TRAF_BIRC3_bd PF16673.5 EGG00026.1 - 0.0064 16.2 2.8 2.3 8.1 0.0 2.9 3 0 0 3 3 3 2 TNF receptor-associated factor BIRC3 binding domain PspA_IM30 PF04012.12 EGG00026.1 - 0.012 15.2 1.6 0.024 14.2 1.6 1.4 1 0 0 1 1 1 0 PspA/IM30 family NADHdh_A3 PF14987.6 EGG00026.1 - 0.013 15.7 0.0 0.049 13.9 0.0 2.0 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 FapA PF03961.13 EGG00026.1 - 0.014 14.1 1.6 0.025 13.2 1.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A NPV_P10 PF05531.12 EGG00026.1 - 0.025 15.0 2.4 0.79 10.2 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EGG00026.1 - 0.027 14.5 1.1 0.082 13.0 0.7 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 EGG00026.1 - 0.072 13.4 3.3 0.22 11.8 3.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 EGG00026.1 - 0.075 13.2 3.7 0.2 11.9 3.7 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4094 PF13334.6 EGG00026.1 - 0.086 13.3 4.9 0.7 10.3 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4094) KLRAQ PF10205.9 EGG00026.1 - 0.15 12.3 2.8 0.28 11.5 1.2 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 EGG00026.1 - 0.25 10.2 7.3 0.46 9.3 7.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 EGG00026.1 - 0.38 11.0 11.3 1.1 9.6 2.9 3.5 2 1 1 3 3 3 0 ABC transporter C-terminal domain XhlA PF10779.9 EGG00026.1 - 0.47 10.7 3.4 2.5 8.4 0.2 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Prefoldin_2 PF01920.20 EGG00026.1 - 0.55 10.2 5.9 6.2 6.8 0.2 2.6 1 1 1 3 3 3 0 Prefoldin subunit FlaC_arch PF05377.11 EGG00026.1 - 0.61 10.5 5.7 4.9 7.6 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 EGG00026.1 - 0.88 10.1 5.6 6.5 7.3 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 CCDC-167 PF15188.6 EGG00026.1 - 0.89 9.9 5.9 0.47 10.8 0.9 2.8 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 SlyX PF04102.12 EGG00026.1 - 1.8 9.3 6.6 3.7 8.2 0.7 2.9 3 0 0 3 3 2 0 SlyX FliJ PF02050.16 EGG00026.1 - 1.8 8.8 11.3 0.14 12.4 5.0 2.2 2 1 1 3 3 2 0 Flagellar FliJ protein V_ATPase_I PF01496.19 EGG00026.1 - 2.7 5.8 5.0 4.5 5.1 5.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4795 PF16043.5 EGG00026.1 - 3.4 7.2 10.3 9.8 5.7 7.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Lzipper-MIP1 PF14389.6 EGG00026.1 - 6.2 7.2 7.8 5.8 7.3 4.6 2.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Fez1 PF06818.15 EGG00027.1 - 0.00047 20.7 1.8 0.00061 20.3 1.8 1.2 1 0 0 1 1 1 1 Fez1 LURAP PF14854.6 EGG00027.1 - 0.0018 18.2 1.2 0.004 17.1 0.6 1.8 1 1 1 2 2 2 1 Leucine rich adaptor protein Tup_N PF08581.10 EGG00027.1 - 0.0092 16.3 2.6 0.063 13.6 1.2 2.6 1 1 1 2 2 2 2 Tup N-terminal CC2-LZ PF16516.5 EGG00027.1 - 0.05 14.0 2.4 0.13 12.7 0.7 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF16 PF01519.16 EGG00027.1 - 0.097 13.2 1.8 0.15 12.5 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 MtrG PF04210.13 EGG00027.1 - 0.13 12.2 0.0 1.3 8.9 0.0 2.2 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G FAM196 PF15265.6 EGG00027.1 - 0.27 10.7 3.3 0.091 12.2 0.9 1.4 2 0 0 2 2 2 0 FAM196 family Sec2p PF06428.11 EGG00027.1 - 0.33 10.9 5.9 0.12 12.4 2.9 1.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Rx_N PF18052.1 EGG00027.1 - 0.49 10.7 3.8 0.48 10.7 0.7 2.3 2 1 1 3 3 3 0 Rx N-terminal domain Fib_alpha PF08702.10 EGG00028.1 - 0.62 10.2 7.6 0.033 14.4 1.8 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Defensin_4 PF07936.12 EGG00031.1 - 0.24 11.3 5.6 0.5 10.3 0.9 2.8 2 0 0 2 2 2 0 Potassium-channel blocking toxin Sec15 PF04091.12 EGG00037.1 - 6.7e-93 311.6 0.0 1.1e-92 310.9 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 EGG00037.1 - 0.00023 21.3 0.8 0.00076 19.7 0.8 1.9 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 EGG00037.1 - 0.0077 16.1 0.7 0.017 15.0 0.7 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Sec5 PF15469.6 EGG00037.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 Exocyst complex component Sec5 Vps51 PF08700.11 EGG00037.1 - 0.072 13.2 0.1 0.79 9.8 0.0 2.5 1 1 1 2 2 2 0 Vps51/Vps67 FlgH PF02107.16 EGG00038.1 - 0.01 15.5 0.1 0.019 14.6 0.0 1.4 1 1 0 1 1 1 1 Flagellar L-ring protein Methyltr_RsmB-F PF01189.17 EGG00040.1 - 4.9e-73 245.1 0.0 7e-73 244.5 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EGG00040.1 - 1.4e-08 35.1 0.0 4e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EGG00040.1 - 0.0013 18.9 0.1 0.0024 18.0 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 EGG00040.1 - 0.046 13.5 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AAA PF00004.29 EGG00041.1 - 3.8e-92 305.6 0.1 6.5e-47 159.3 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG00041.1 - 2.3e-19 68.9 0.1 5.7e-09 35.6 0.1 2.5 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EGG00041.1 - 6.2e-14 52.0 0.0 1.6e-06 28.0 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGG00041.1 - 3.7e-13 50.0 0.0 2.1e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGG00041.1 - 4.2e-13 49.7 2.1 0.00077 19.8 0.2 4.7 3 2 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EGG00041.1 - 2.9e-11 43.5 0.2 0.00056 19.9 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGG00041.1 - 2e-10 41.3 3.1 0.0021 18.5 0.0 4.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EGG00041.1 - 2.7e-10 40.5 0.0 0.00079 19.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EGG00041.1 - 8.4e-09 35.1 0.2 0.0019 17.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGG00041.1 - 1.5e-08 34.7 0.0 0.0035 17.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGG00041.1 - 2.2e-08 34.7 0.0 0.0011 19.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EGG00041.1 - 9.4e-08 32.0 0.1 0.0077 16.0 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 EGG00041.1 - 2e-07 31.4 0.0 0.025 15.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.13 EGG00041.1 - 2e-07 30.6 0.1 0.0055 15.9 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Rad17 PF03215.15 EGG00041.1 - 2.7e-07 30.7 0.0 0.0017 18.3 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_28 PF13521.6 EGG00041.1 - 1.9e-06 28.2 0.0 0.04 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EGG00041.1 - 3.6e-06 27.0 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EGG00041.1 - 6e-06 26.8 0.1 0.37 11.3 0.0 3.6 3 0 0 3 3 3 2 ABC transporter AAA_25 PF13481.6 EGG00041.1 - 8e-06 25.6 1.0 0.68 9.5 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_7 PF12775.7 EGG00041.1 - 8.7e-06 25.4 0.0 0.077 12.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_17 PF13207.6 EGG00041.1 - 1.4e-05 25.6 0.0 0.026 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGG00041.1 - 2.6e-05 24.2 2.3 0.29 11.0 0.1 3.8 3 1 1 4 4 4 2 NACHT domain ATPase PF06745.13 EGG00041.1 - 3e-05 23.5 0.4 0.84 8.9 0.0 3.5 2 1 1 3 3 3 2 KaiC DUF815 PF05673.13 EGG00041.1 - 5.2e-05 22.5 0.0 0.056 12.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.11 EGG00041.1 - 0.0001 22.1 0.0 0.53 10.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 EGG00041.1 - 0.00014 22.0 0.0 0.52 10.4 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 EGG00041.1 - 0.00014 21.1 0.0 0.25 10.5 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.12 EGG00041.1 - 0.00015 21.1 0.0 0.29 10.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.6 EGG00041.1 - 0.0002 21.2 0.0 0.81 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EGG00041.1 - 0.00045 20.2 0.0 0.96 9.5 0.0 2.7 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.26 EGG00041.1 - 0.00059 19.6 0.0 0.48 10.1 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EGG00041.1 - 0.00067 18.8 0.2 0.74 8.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.18 EGG00041.1 - 0.0012 18.7 0.3 1 9.1 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.6 EGG00041.1 - 0.0013 18.9 0.0 0.47 10.6 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family ATPase_2 PF01637.18 EGG00041.1 - 0.0015 18.5 0.0 1.7 8.5 0.0 3.3 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EGG00041.1 - 0.0024 17.7 0.3 1.6 8.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 EGG00041.1 - 0.0051 16.7 0.1 5.4 6.9 0.0 2.8 2 1 1 3 3 2 0 NTPase SKI PF01202.22 EGG00041.1 - 0.0057 16.8 0.1 4 7.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_19 PF13245.6 EGG00041.1 - 0.0071 16.7 0.4 3.7 7.9 0.2 3.2 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EGG00041.1 - 0.008 15.9 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.16 EGG00041.1 - 0.0096 15.4 0.1 3 7.2 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein PduV-EutP PF10662.9 EGG00041.1 - 0.016 15.0 0.0 8.3 6.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 EGG00041.1 - 0.016 14.6 0.0 12 5.2 0.0 3.5 2 1 0 3 3 3 0 Bacterial TniB protein Cytidylate_kin PF02224.18 EGG00041.1 - 0.036 13.8 0.2 11 5.6 0.1 2.7 2 0 0 2 2 2 0 Cytidylate kinase MCM PF00493.23 EGG00041.1 - 0.063 12.4 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain Bac_DnaA PF00308.18 EGG00041.1 - 0.07 13.0 0.0 4.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein ADK PF00406.22 EGG00041.1 - 0.12 12.5 0.1 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Adenylate kinase SRPRB PF09439.10 EGG00041.1 - 0.12 11.8 0.5 22 4.4 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Zot PF05707.12 EGG00041.1 - 0.14 11.8 0.1 2.4 7.7 0.0 2.8 2 2 0 2 2 2 0 Zonular occludens toxin (Zot) G-patch PF01585.23 EGG00042.1 - 5.8e-09 35.7 0.6 3.1e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 G-patch domain CxC1 PF18802.1 EGG00045.1 - 3.1e-19 69.1 0.1 1.9e-16 60.1 0.1 2.4 1 1 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG00045.1 - 0.18 12.0 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases IL1 PF00340.19 EGG00047.1 - 0.14 11.9 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Interleukin-1 / 18 Cyclin_N PF00134.23 EGG00049.1 - 1.3e-12 47.6 1.1 2.2e-12 46.8 0.5 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 EGG00049.1 - 0.00089 19.3 0.9 0.0028 17.6 0.6 2.0 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 EGG00049.1 - 0.0021 18.4 0.0 0.0052 17.1 0.0 1.7 1 0 0 1 1 1 1 Cyclin C-terminal domain DnaJ PF00226.31 EGG00050.1 - 7.6e-05 22.8 0.1 0.00011 22.2 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 EGG00050.1 - 0.00086 19.3 0.0 0.00098 19.1 0.0 1.1 1 0 0 1 1 1 1 Pam16 SRP14 PF02290.15 EGG00051.1 - 1.1 9.7 3.2 0.85 10.0 0.3 2.1 2 0 0 2 2 2 0 Signal recognition particle 14kD protein NPR1_interact PF15699.5 EGG00052.1 - 0.044 14.4 0.4 0.31 11.7 0.1 2.1 2 0 0 2 2 2 0 NPR1 interacting Bot1p PF12298.8 EGG00053.1 - 5.4e-16 59.2 2.8 3e-10 40.5 0.7 2.6 1 1 1 2 2 2 2 Eukaryotic mitochondrial regulator protein Ubiquitin_5 PF18037.1 EGG00053.1 - 0.036 14.4 0.1 0.11 12.8 0.1 1.9 1 0 0 1 1 1 0 Ubiquitin-like domain Glyco_hydro_18 PF00704.28 EGG00054.1 - 2.1e-56 191.9 0.0 2.4e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ING PF12998.7 EGG00055.1 - 2.1e-09 37.9 0.5 0.00034 21.1 0.3 2.2 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGG00055.1 - 5.1e-06 26.3 8.7 1e-05 25.3 8.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EGG00055.1 - 0.00011 22.4 1.1 0.00024 21.3 1.1 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Toxin_34 PF08396.10 EGG00055.1 - 0.071 13.9 2.9 0.13 13.0 2.9 1.4 1 0 0 1 1 1 0 Spider toxin omega agatoxin/Tx1 family Pec_lyase_C PF00544.19 EGG00056.1 - 4.1e-12 46.1 8.7 3.6e-11 43.1 8.7 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EGG00056.1 - 0.11 12.3 12.4 0.29 11.0 12.4 1.7 1 1 0 1 1 1 0 Right handed beta helix region PgdA_N PF18627.1 EGG00056.1 - 0.32 10.6 1.3 0.59 9.7 1.3 1.3 1 0 0 1 1 1 0 Peptidoglycan GlcNAc deacetylase N-terminal domain RasGAP PF00616.19 EGG00057.1 - 1.3e-28 100.1 0.1 6.8e-20 71.7 0.0 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EGG00057.1 - 2.4e-06 27.7 0.1 9e-06 25.9 0.1 2.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Telomere_reg-2 PF10193.9 EGG00057.1 - 0.041 14.3 0.1 0.25 11.8 0.1 2.4 1 0 0 1 1 1 0 Telomere length regulation protein SBF2 PF12335.8 EGG00059.1 - 0.35 10.4 5.7 0.46 10.1 5.7 1.0 1 0 0 1 1 1 0 Myotubularin protein DUF3987 PF13148.6 EGG00059.1 - 1.5 7.8 8.9 1.8 7.5 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF1682 PF07946.14 EGG00059.1 - 1.7 7.7 11.5 2 7.5 11.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pkinase_Tyr PF07714.17 EGG00060.1 - 1.7e-43 148.8 0.0 2.4e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG00060.1 - 1.7e-39 135.8 0.0 2.9e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGG00060.1 - 0.00075 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG00060.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SKA1 PF07160.12 EGG00061.1 - 0.28 11.0 4.7 0.41 10.4 4.7 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 PyrI_C PF02748.15 EGG00062.1 - 0.017 15.0 0.4 0.043 13.7 0.4 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain MTCP1 PF08991.10 EGG00064.1 - 3.4e-20 72.0 12.5 3.9e-20 71.8 12.5 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Wtap PF17098.5 EGG00064.1 - 0.018 15.0 0.4 0.02 14.8 0.4 1.1 1 0 0 1 1 1 0 WTAP/Mum2p family SOBP PF15279.6 EGG00065.1 - 0.12 13.0 10.1 0.24 12.0 10.1 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein FB_lectin PF07367.11 EGG00065.1 - 0.18 11.7 1.5 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Fungal fruit body lectin PI3K_1B_p101 PF10486.9 EGG00065.1 - 0.29 8.9 23.0 0.4 8.4 23.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit eIF-3c_N PF05470.12 EGG00065.1 - 0.38 9.0 13.6 0.61 8.3 13.6 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus LAP1C PF05609.12 EGG00065.1 - 1.1 8.2 18.3 1.6 7.7 18.3 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RR_TM4-6 PF06459.12 EGG00065.1 - 2.7 7.7 18.4 4.8 6.9 18.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 EGG00065.1 - 5.6 4.0 14.9 7.3 3.6 14.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Nop14 PF04147.12 EGG00065.1 - 5.9 5.0 30.5 8.9 4.4 30.5 1.2 1 0 0 1 1 1 0 Nop14-like family Fes1 PF08609.10 EGG00066.1 - 4.5e-22 78.7 2.3 8.1e-22 77.9 1.3 2.0 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 DUF3361 PF11841.8 EGG00066.1 - 0.00042 20.3 0.9 0.011 15.6 0.5 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF3361) Arm PF00514.23 EGG00066.1 - 0.0049 16.9 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat SIL1 PF16782.5 EGG00066.1 - 0.0067 15.7 1.7 0.014 14.6 0.3 1.7 1 1 1 2 2 2 1 Nucleotide exchange factor SIL1 HEAT_2 PF13646.6 EGG00066.1 - 0.044 14.2 0.0 1.3 9.5 0.0 2.5 1 1 1 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 EGG00066.1 - 0.13 12.8 0.0 27 5.4 0.0 2.5 2 0 0 2 2 2 0 HEAT-like repeat PI3K_1B_p101 PF10486.9 EGG00068.1 - 0.86 7.3 25.3 1.2 6.8 25.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SOBP PF15279.6 EGG00068.1 - 1.7 9.2 11.6 3.4 8.2 11.6 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.9 EGG00068.1 - 2.1 6.8 16.7 3.3 6.2 16.7 1.4 1 0 0 1 1 1 0 Macoilin family VIR_N PF15912.5 EGG00068.1 - 3.5 7.1 18.2 7.6 6.0 18.2 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal GREB1 PF15782.5 EGG00068.1 - 9.4 3.2 16.4 12 2.9 16.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CBFD_NFYB_HMF PF00808.23 EGG00069.1 - 1.6e-11 44.3 0.0 4.1e-09 36.6 0.0 2.2 1 1 1 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGG00069.1 - 0.016 15.6 2.4 0.037 14.4 2.4 1.6 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 eIF2_C PF09173.11 EGG00070.1 - 2.5e-36 123.8 0.4 6.9e-36 122.4 0.4 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EGG00070.1 - 6e-23 81.4 0.8 5.4e-22 78.3 0.8 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGG00070.1 - 3.8e-10 40.0 0.9 3.8e-10 40.0 0.9 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGG00070.1 - 0.0021 18.1 0.0 0.0084 16.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG00070.1 - 0.0022 18.0 0.7 0.036 14.0 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EGG00070.1 - 0.0036 17.3 0.1 0.0091 16.0 0.1 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 EGG00070.1 - 0.05 12.7 0.1 0.42 9.7 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Elicitin PF00964.17 EGG00070.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Elicitin WLM PF08325.10 EGG00074.1 - 2.3e-09 37.6 10.2 3.8e-08 33.6 2.3 3.8 2 1 2 4 4 4 2 WLM domain DUF45 PF01863.17 EGG00074.1 - 0.61 10.1 0.0 0.61 10.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF45 Pyr_redox_2 PF07992.14 EGG00076.1 - 3.1e-70 236.7 0.5 4.2e-70 236.3 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGG00076.1 - 7e-35 119.6 4.4 8.7e-35 119.3 1.1 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGG00076.1 - 4.6e-25 88.0 1.5 5.2e-19 68.6 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG00076.1 - 2e-20 73.2 1.4 2.6e-15 56.5 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGG00076.1 - 1.9e-11 44.0 0.1 4e-11 42.9 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG00076.1 - 5.4e-09 35.2 0.7 9.5e-05 21.3 0.6 3.2 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 EGG00076.1 - 1.7e-06 28.2 1.2 4.7e-06 26.7 1.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGG00076.1 - 3.7e-06 26.3 3.2 9.9e-06 24.9 2.6 1.8 2 1 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EGG00076.1 - 5.2e-06 25.9 0.1 1.3e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 EGG00076.1 - 8.9e-06 25.1 0.0 0.0015 17.8 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 EGG00076.1 - 4.1e-05 23.5 0.4 0.069 13.0 0.0 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EGG00076.1 - 4.3e-05 22.8 2.0 0.0003 20.0 1.3 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EGG00076.1 - 0.0006 19.2 0.3 0.13 11.5 0.3 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EGG00076.1 - 0.0014 18.3 5.0 0.0014 18.3 5.0 3.4 3 1 1 4 4 4 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EGG00076.1 - 0.0035 16.7 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EGG00076.1 - 0.0042 16.4 0.8 0.42 9.8 0.7 2.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 EGG00076.1 - 0.006 17.0 0.5 0.81 10.2 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EGG00076.1 - 0.012 14.7 0.5 0.048 12.7 1.0 1.9 2 1 0 2 2 2 0 Lycopene cyclase protein XdhC_C PF13478.6 EGG00076.1 - 0.14 12.6 0.4 18 5.8 0.0 2.8 3 0 0 3 3 2 0 XdhC Rossmann domain UPF0061 PF02696.14 EGG00077.1 - 0.13 11.1 3.3 0.25 10.1 3.3 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family LRR19-TM PF15176.6 EGG00077.1 - 3.8 7.5 6.8 2.6 8.1 2.3 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain TOM13 PF08219.11 EGG00078.1 - 1.2e-10 41.2 6.9 3.7e-10 39.6 6.0 2.3 1 1 1 2 2 2 1 Outer membrane protein TOM13 ABC2_membrane PF01061.24 EGG00080.1 - 4.7e-34 117.6 21.6 4.7e-34 117.6 21.6 2.7 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 EGG00080.1 - 6.3e-27 94.8 0.1 1.1e-26 94.0 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGG00080.1 - 5.7e-06 26.4 0.1 0.056 13.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system EGF_2 PF07974.13 EGG00080.1 - 0.00087 19.6 28.3 0.0054 17.1 12.4 3.7 3 0 0 3 3 3 2 EGF-like domain AAA_16 PF13191.6 EGG00080.1 - 0.0017 18.8 0.0 0.0039 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGG00080.1 - 0.0052 16.7 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGG00080.1 - 0.0063 16.2 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGG00080.1 - 0.012 15.1 0.3 0.36 10.2 0.1 2.5 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 EGG00080.1 - 0.013 14.7 29.3 0.0074 15.4 25.7 2.3 2 1 0 2 2 2 0 ABC-2 family transporter protein Rad17 PF03215.15 EGG00080.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 1 0 Rad17 P-loop domain hEGF PF12661.7 EGG00080.1 - 0.048 14.3 19.4 0.76 10.5 6.8 4.1 3 0 0 3 3 3 0 Human growth factor-like EGF MHYT PF03707.16 EGG00080.1 - 1.2 9.4 0.0 1.2 9.4 0.0 4.0 4 0 0 4 4 4 0 Bacterial signalling protein N terminal repeat Laminin_EGF PF00053.24 EGG00080.1 - 4.9 7.4 34.7 0.33 11.1 9.9 3.8 2 1 1 3 3 3 0 Laminin EGF domain CxC1 PF18802.1 EGG00083.1 - 4e-14 52.6 1.3 9.3e-14 51.4 1.3 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG00083.1 - 6.6e-07 29.5 0.9 1.4e-06 28.4 0.9 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG00083.1 - 0.034 14.0 0.5 0.067 13.0 0.5 1.5 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases UPF0227 PF05728.12 EGG00083.1 - 0.063 13.2 0.3 0.15 12.0 0.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ribosomal_L30_N PF08079.12 EGG00083.1 - 0.37 11.1 5.4 8.9 6.7 0.0 3.1 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain PPR_2 PF13041.6 EGG00085.1 - 9.1e-07 29.0 0.0 0.012 15.8 0.0 3.7 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 EGG00085.1 - 1.2e-06 28.5 0.0 0.0052 16.8 0.0 3.0 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGG00085.1 - 0.019 14.7 0.0 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 PPR repeat PPR PF01535.20 EGG00085.1 - 0.056 13.7 0.1 19 5.7 0.0 4.4 5 0 0 5 5 5 0 PPR repeat ARD PF03079.14 EGG00087.1 - 6.3e-29 101.2 1.5 8.1e-29 100.8 1.5 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EGG00087.1 - 0.011 15.4 0.3 0.031 14.0 0.1 1.9 3 0 0 3 3 3 0 Cupin domain S8_pro-domain PF16470.5 EGG00087.1 - 0.032 15.0 0.1 0.17 12.7 0.0 2.1 1 1 0 1 1 1 0 Peptidase S8 pro-domain SecA_SW PF07516.13 EGG00087.1 - 0.081 13.0 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 SecA Wing and Scaffold domain RRM_1 PF00076.22 EGG00088.1 - 1.5e-17 63.2 0.0 5.6e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG00088.1 - 0.0012 18.4 0.0 0.067 12.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG00088.1 - 0.0027 17.5 0.0 0.21 11.4 0.0 2.5 2 1 0 2 2 2 1 Occluded RNA-recognition motif Calcipressin PF04847.12 EGG00088.1 - 0.014 15.1 0.0 5.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Calcipressin Alpha_kinase PF02816.18 EGG00089.1 - 1.2e-12 48.3 0.8 1.7e-12 47.8 0.8 1.2 1 0 0 1 1 1 1 Alpha-kinase family bZIP_1 PF00170.21 EGG00092.1 - 6.3e-05 23.0 9.3 9.7e-05 22.4 9.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor Band_3_cyto PF07565.13 EGG00092.1 - 0.0021 17.9 1.8 0.0026 17.6 1.8 1.1 1 0 0 1 1 1 1 Band 3 cytoplasmic domain DUF5094 PF17015.5 EGG00092.1 - 0.0032 17.6 5.3 0.0043 17.2 5.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5094) bZIP_2 PF07716.15 EGG00092.1 - 0.03 14.4 16.7 0.78 9.9 15.4 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Mem_trans PF03547.18 EGG00092.1 - 0.18 10.2 1.6 0.22 9.9 1.6 1.1 1 0 0 1 1 1 0 Membrane transport protein CCDC106 PF15794.5 EGG00092.1 - 2.6 7.7 14.9 0.19 11.4 0.4 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 Presenilin PF01080.17 EGG00092.1 - 4.3 6.0 6.9 5 5.8 6.9 1.1 1 0 0 1 1 1 0 Presenilin PRKCSH PF07915.13 EGG00093.1 - 1.1e-11 45.6 1.1 1.3e-10 42.2 0.0 3.1 2 2 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EGG00093.1 - 0.0085 15.8 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF3395 PF11875.8 EGG00093.1 - 0.093 12.6 1.4 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) MID_MedPIWI PF18296.1 EGG00093.1 - 0.55 10.0 7.5 0.18 11.6 3.9 1.9 2 0 0 2 2 2 0 MID domain of medPIWI Suf PF05843.14 EGG00093.1 - 5.3 6.9 6.2 10 6.0 6.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Epimerase PF01370.21 EGG00095.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RabGAP-TBC PF00566.18 EGG00096.1 - 1e-29 103.8 8.9 1.2e-12 48.0 0.1 4.2 3 1 0 3 3 3 3 Rab-GTPase-TBC domain F-box-like PF12937.7 EGG00102.1 - 0.00035 20.4 0.1 0.00081 19.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EGG00102.1 - 5.2 7.6 8.7 3.1 8.3 3.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) CPG4 PF15481.6 EGG00104.1 - 0.034 14.8 0.3 0.068 13.8 0.3 1.6 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 DUF2634 PF10934.8 EGG00104.1 - 0.085 13.0 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) Nop16 PF09420.10 EGG00106.1 - 0.093 12.8 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 FAM104 PF15434.6 EGG00109.1 - 1.8 9.1 5.5 0.39 11.3 1.5 2.0 2 1 0 2 2 2 0 Family 104 Synaptobrevin PF00957.21 EGG00112.1 - 3e-34 116.7 0.6 3.4e-34 116.5 0.6 1.0 1 0 0 1 1 1 1 Synaptobrevin CxC6 PF18721.1 EGG00114.1 - 3.4e-09 36.8 0.3 1.4e-08 34.9 0.3 2.1 1 1 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases Trypan_PARP PF05887.11 EGG00115.1 - 0.085 12.8 16.3 0.2 11.7 16.3 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) YkpC PF17447.2 EGG00115.1 - 0.52 11.2 0.1 0.52 11.2 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized YkpC-like Neur_chan_memb PF02932.16 EGG00115.1 - 3.1 7.8 8.5 0.88 9.6 5.4 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF778 PF05608.12 EGG00115.1 - 3.1 8.1 6.8 7.2 6.9 6.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Peptidase_S30 PF01577.16 EGG00115.1 - 5 6.7 12.1 9.1 5.8 12.1 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease PAS_9 PF13426.7 EGG00118.1 - 5.1e-17 62.0 0.0 3.1e-16 59.5 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EGG00118.1 - 0.0025 17.8 0.0 0.0093 16.0 0.0 1.9 1 0 0 1 1 1 1 PAS fold SH3BGR PF04908.15 EGG00118.1 - 0.06 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein NAC PF01849.18 EGG00119.1 - 1.1e-20 73.4 0.1 1.8e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 NAC domain Aminotran_3 PF00202.21 EGG00120.1 - 1.9e-109 366.0 0.0 2.6e-109 365.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGG00120.1 - 0.0013 17.9 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Serine_rich PF08824.10 EGG00120.1 - 0.017 15.1 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF2623 PF11115.8 EGG00120.1 - 0.13 12.4 0.1 1 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2623) Ribosomal_L11_N PF03946.14 EGG00121.1 - 7.3e-24 83.4 0.0 1.1e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGG00121.1 - 1.5e-22 79.9 0.0 2.1e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Late_protein_L2 PF00513.18 EGG00121.1 - 0.029 13.4 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 Late Protein L2 Ctf8 PF09696.10 EGG00122.1 - 8e-16 58.7 0.3 3.4e-15 56.6 0.3 1.9 1 1 0 1 1 1 1 Ctf8 Glycogen_syn PF05693.13 EGG00124.1 - 0 1144.2 0.0 0 1144.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_trans_1_4 PF13692.6 EGG00124.1 - 1.1e-06 29.1 0.0 0.0023 18.4 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGG00124.1 - 1.1e-06 28.3 0.0 0.0002 20.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EGG00124.1 - 6e-06 26.1 0.0 1.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 EGG00124.1 - 0.0002 21.4 0.1 0.00037 20.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGG00124.1 - 0.00073 20.0 0.0 0.0019 18.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF1978 PF09321.10 EGG00124.1 - 0.013 14.8 0.2 0.21 10.9 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1978) Coiled PF05710.12 EGG00125.1 - 1.7 9.5 9.0 3.2 8.6 9.0 1.5 1 0 0 1 1 1 0 Coiled coil Annexin PF00191.20 EGG00128.1 - 0.035 14.2 0.2 0.096 12.8 0.0 1.8 2 0 0 2 2 2 0 Annexin EST1_DNA_bind PF10373.9 EGG00129.1 - 0.013 15.0 0.5 0.015 14.8 0.5 1.0 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain SPACA9 PF15120.6 EGG00129.1 - 0.023 14.5 0.1 0.024 14.4 0.1 1.1 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 SARAF PF06682.12 EGG00130.1 - 1e-15 58.2 0.3 3.3e-15 56.6 0.3 1.8 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis PHY PF00360.20 EGG00131.1 - 1.5e-25 89.6 0.1 4.6e-25 88.0 0.0 1.8 2 0 0 2 2 2 1 Phytochrome region HATPase_c PF02518.26 EGG00131.1 - 2.9e-23 82.5 0.3 6.8e-23 81.3 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGG00131.1 - 1.8e-18 66.7 0.1 6.2e-18 65.0 0.1 1.9 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 EGG00131.1 - 7.4e-14 52.5 0.0 2.4e-13 50.8 0.0 2.0 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 EGG00131.1 - 4.2e-12 45.9 1.9 1e-11 44.7 1.9 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 EGG00131.1 - 4.8e-08 33.6 1.0 1.5e-07 32.0 0.1 2.4 2 0 0 2 2 2 1 PAS fold Claudin_3 PF06653.11 EGG00132.1 - 0.051 13.5 3.6 0.09 12.7 3.6 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Gemini_mov PF01708.16 EGG00132.1 - 4.9 7.0 5.2 34 4.3 2.2 3.2 3 1 1 4 4 4 0 Geminivirus putative movement protein DUF2408 PF10303.9 EGG00133.1 - 0.0038 17.8 1.3 0.024 15.2 1.3 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) ApoLp-III PF07464.11 EGG00133.1 - 0.16 12.0 1.8 0.41 10.7 1.8 1.6 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) SLT PF01464.20 EGG00134.1 - 4.5e-13 48.9 0.0 8.8e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 EGG00134.1 - 0.093 13.2 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase DUF3449 PF11931.8 EGG00135.1 - 4.1e-74 248.4 3.8 3.7e-73 245.2 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EGG00135.1 - 5.4e-24 84.5 2.7 6.9e-24 84.2 0.7 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-met PF12874.7 EGG00135.1 - 2.1e-07 31.1 9.5 1e-05 25.8 4.0 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.8 EGG00135.1 - 3.1e-06 27.0 0.1 1.1e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 EGG00135.1 - 6.2e-06 26.4 2.9 6.2e-06 26.4 2.9 2.8 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGG00135.1 - 0.0043 17.4 1.1 0.12 12.7 0.1 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF5329 PF17263.2 EGG00135.1 - 0.055 13.6 0.6 0.12 12.6 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5329) AlkA_N PF06029.11 EGG00135.1 - 0.089 13.1 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 AlkA N-terminal domain zf-DBF PF07535.12 EGG00135.1 - 0.17 12.0 5.1 1.3 9.2 0.1 3.1 3 0 0 3 3 3 0 DBF zinc finger CCDC53 PF10152.9 EGG00135.1 - 0.2 12.1 2.1 0.48 10.8 2.1 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Laps PF10169.9 EGG00135.1 - 0.21 12.2 3.7 1.2 9.7 0.1 2.4 2 0 0 2 2 2 0 Learning-associated protein CENP-O PF09496.10 EGG00135.1 - 0.35 10.8 3.8 2.4 8.1 3.6 2.3 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component SRP72 PF08492.12 EGG00137.1 - 1e-05 25.8 5.3 1e-05 25.8 5.3 2.7 2 1 0 2 2 2 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 EGG00137.1 - 0.0025 17.8 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative TPR-like repeat ANAPC3 PF12895.7 EGG00137.1 - 0.0081 16.4 0.1 0.012 15.8 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGG00137.1 - 0.019 15.5 0.0 0.034 14.7 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG00137.1 - 0.03 14.4 0.2 0.072 13.2 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG00137.1 - 0.054 13.5 0.4 0.28 11.3 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG00137.1 - 0.082 13.8 0.0 0.15 12.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat NARP1 PF12569.8 EGG00137.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 EGG00137.1 - 0.16 12.3 0.2 0.43 10.9 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG00137.1 - 0.2 12.0 0.8 0.96 9.8 0.3 1.8 1 1 0 2 2 2 0 Tetratricopeptide repeat PXA PF02194.15 EGG00138.1 - 2.3 8.1 5.0 3.4 7.6 5.0 1.2 1 0 0 1 1 1 0 PXA domain Asp-B-Hydro_N PF05279.11 EGG00138.1 - 2.9 7.9 22.4 3.9 7.5 22.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Atg14 PF10186.9 EGG00138.1 - 4.5 6.3 14.1 5.2 6.1 14.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PAT1 PF09770.9 EGG00138.1 - 5.1 5.2 14.2 5.5 5.1 14.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ECF_trnsprt PF12822.7 EGG00139.1 - 0.16 12.0 10.6 0.063 13.4 1.4 2.7 2 1 0 2 2 2 0 ECF transporter, substrate-specific component CPP1-like PF11833.8 EGG00139.1 - 2.2 7.9 7.2 9.2 5.9 0.6 2.3 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like RRF PF01765.19 EGG00140.1 - 2e-35 122.1 0.9 2.4e-35 121.9 0.9 1.0 1 0 0 1 1 1 1 Ribosome recycling factor 14-3-3 PF00244.20 EGG00140.1 - 0.008 15.7 1.2 0.012 15.1 1.2 1.2 1 0 0 1 1 1 1 14-3-3 protein DUF3602 PF12223.8 EGG00141.1 - 7.9e-15 55.2 12.3 8.6e-10 39.1 2.0 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) DEC-1_N PF04625.13 EGG00142.1 - 0.0095 15.0 1.0 0.012 14.7 1.0 1.1 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region COG2 PF06148.11 EGG00143.1 - 0.0012 18.9 0.8 0.003 17.6 0.5 1.7 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 EGG00143.1 - 0.0022 18.1 1.4 0.0022 18.1 1.4 1.8 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Focal_AT PF03623.13 EGG00143.1 - 0.01 15.8 1.3 0.14 12.2 0.6 2.3 2 0 0 2 2 2 0 Focal adhesion targeting region Apolipoprotein PF01442.18 EGG00143.1 - 0.021 14.7 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Fzo_mitofusin PF04799.13 EGG00143.1 - 0.03 13.9 1.3 0.22 11.1 1.2 2.0 2 0 0 2 2 2 0 fzo-like conserved region DUF1640 PF07798.11 EGG00143.1 - 0.063 13.3 0.7 0.11 12.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Use1 PF09753.9 EGG00143.1 - 0.08 12.7 0.7 0.13 12.0 0.7 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 CSN5_C PF18323.1 EGG00143.1 - 0.088 13.7 0.0 0.54 11.2 0.0 2.5 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Mis14 PF08641.12 EGG00143.1 - 0.096 13.0 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Kinetochore protein Mis14 like SH3_1 PF00018.28 EGG00144.1 - 2.1e-21 75.2 0.0 2.5e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EGG00144.1 - 6.2e-16 58.0 0.0 3.1e-08 33.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 EGG00144.1 - 3.9e-14 52.1 0.5 1.2e-07 31.3 0.0 3.3 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.24 EGG00144.1 - 3.5e-11 43.1 0.4 1e-10 41.6 0.4 1.8 1 0 0 1 1 1 1 PX domain Coiled PF05710.12 EGG00144.1 - 4.2 8.3 6.6 2.9 8.8 2.5 2.7 2 0 0 2 2 2 0 Coiled coil Pol_alpha_B_N PF08418.10 EGG00144.1 - 4.7 7.1 11.9 0.97 9.4 3.0 3.3 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal CRIM PF16978.5 EGG00146.1 - 4e-44 150.2 0.0 7.9e-44 149.2 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EGG00146.1 - 3.9e-16 59.3 0.0 1.2e-15 57.7 0.0 1.9 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 EGG00146.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 TUG ubiquitin-like domain HTH_DeoR PF08220.12 EGG00147.1 - 0.0003 20.5 2.0 2.3 8.0 0.0 3.6 3 0 0 3 3 3 3 DeoR-like helix-turn-helix domain Hce2 PF14856.6 EGG00147.1 - 0.0092 16.3 0.9 50 4.3 0.0 4.3 4 0 0 4 4 4 0 Pathogen effector; putative necrosis-inducing factor DUF1687 PF07955.11 EGG00147.1 - 0.14 12.6 0.0 1.4e+02 2.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1687) T6SS_VasJ PF16989.5 EGG00147.1 - 0.14 11.6 1.5 5.5 6.4 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ MutL_C PF08676.11 EGG00148.1 - 0.00086 19.1 0.0 0.0063 16.3 0.1 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain BrnT_toxin PF04365.13 EGG00148.1 - 0.057 13.8 0.4 0.19 12.1 0.4 1.9 1 0 0 1 1 1 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system Bud13 PF09736.9 EGG00151.1 - 1.5e-50 171.3 3.3 1.5e-50 171.3 3.3 3.0 1 1 2 3 3 3 1 Pre-mRNA-splicing factor of RES complex Frataxin_Cyay PF01491.16 EGG00154.1 - 5.9e-35 119.6 0.0 7.3e-35 119.3 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain dCMP_cyt_deam_1 PF00383.23 EGG00155.1 - 0.00078 19.3 0.2 0.0013 18.6 0.2 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region S1 PF00575.23 EGG00156.1 - 7.4e-09 35.8 0.2 1.8e-08 34.6 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Interferon PF00143.19 EGG00156.1 - 0.4 10.8 4.3 0.11 12.7 0.9 1.7 2 0 0 2 2 2 0 Interferon alpha/beta domain OB_NTP_bind PF07717.16 EGG00157.1 - 1.4e-24 86.2 0.0 2.6e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EGG00157.1 - 1.2e-23 83.4 0.1 2.6e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGG00157.1 - 4.5e-13 49.5 0.0 1.1e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cys_Met_Meta_PP PF01053.20 EGG00158.1 - 3.9e-120 400.9 0.0 5.9e-120 400.3 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGG00158.1 - 5.3e-06 25.8 0.0 7.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGG00158.1 - 5.6e-05 22.3 0.1 9e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGG00158.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase IMS PF00817.20 EGG00158.1 - 0.19 11.7 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 impB/mucB/samB family FA_desaturase PF00487.24 EGG00159.1 - 9e-31 107.6 14.7 1.1e-30 107.4 14.7 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Rad17 PF03215.15 EGG00160.1 - 1.9e-17 63.8 1.1 2.7e-11 43.7 0.0 3.1 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_22 PF13401.6 EGG00160.1 - 0.00036 20.8 0.1 0.0061 16.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG00160.1 - 0.00045 20.6 0.2 0.012 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain L_protein_N PF15518.6 EGG00160.1 - 0.024 14.5 0.1 2.8 7.8 0.0 2.9 3 0 0 3 3 3 0 L protein N-terminus NACHT PF05729.12 EGG00160.1 - 0.046 13.6 0.1 0.93 9.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EGG00160.1 - 0.08 12.7 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_assoc_2 PF16193.5 EGG00160.1 - 0.13 12.7 0.0 0.47 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA C-terminal domain AAA PF00004.29 EGG00160.1 - 0.13 12.7 0.0 0.9 10.0 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EGG00160.1 - 0.89 9.2 5.0 0.74 9.5 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Peptidase_S10 PF00450.22 EGG00161.1 - 1.8e-77 261.5 1.1 5.5e-77 259.9 1.1 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Thaumatin PF00314.17 EGG00162.1 - 2.2e-18 66.7 2.6 2.8e-18 66.4 2.6 1.2 1 0 0 1 1 1 1 Thaumatin family SHMT PF00464.19 EGG00163.1 - 3.4e-174 579.1 0.0 3.9e-174 578.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EGG00163.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase NTP_transferase PF00483.23 EGG00170.1 - 3.9e-53 180.6 0.0 5.1e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EGG00170.1 - 4.1e-11 43.5 0.0 5.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EGG00170.1 - 4.8e-07 29.3 9.4 1e-05 25.0 2.2 3.8 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EGG00170.1 - 0.00046 18.5 0.1 0.00068 17.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EGG00170.1 - 0.0082 15.9 5.3 0.012 15.4 1.3 3.1 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 EGG00170.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 EGG00170.1 - 0.079 12.9 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Cytidylyltransferase SRP54 PF00448.22 EGG00170.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DnaJ PF00226.31 EGG00171.1 - 5.7e-05 23.2 0.2 0.0022 18.1 0.1 3.5 2 1 0 2 2 2 1 DnaJ domain DUF1394 PF07159.12 EGG00172.1 - 3e-05 23.4 0.2 5.4e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) PknG_TPR PF16918.5 EGG00172.1 - 0.0024 16.7 1.1 0.023 13.4 0.2 2.2 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat DnaJ PF00226.31 EGG00172.1 - 0.0043 17.1 1.9 0.0092 16.1 0.2 2.5 2 0 0 2 2 2 1 DnaJ domain DUF5446 PF17522.2 EGG00172.1 - 0.039 14.1 1.6 0.31 11.2 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5446) TMF_TATA_bd PF12325.8 EGG00172.1 - 0.069 13.4 6.9 2.8 8.2 0.8 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SKA1 PF07160.12 EGG00172.1 - 0.19 11.6 5.5 1.2 8.9 0.8 2.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 SKA2 PF16740.5 EGG00172.1 - 0.65 9.8 8.2 1.2 8.9 1.2 2.8 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 zf-CCHC PF00098.23 EGG00174.1 - 2.9e-05 23.9 16.6 0.0021 18.1 2.9 3.1 2 1 0 2 2 2 2 Zinc knuckle Rad50_zn_hook PF04423.14 EGG00174.1 - 0.0095 15.8 0.8 0.038 13.8 0.8 2.0 1 0 0 1 1 1 1 Rad50 zinc hook motif zf-CCHC_4 PF14392.6 EGG00174.1 - 0.014 15.2 7.5 0.13 12.0 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 EGG00174.1 - 0.033 14.0 12.9 0.086 12.7 1.8 2.9 3 0 0 3 3 3 0 Zinc knuckle Mut7-C PF01927.16 EGG00174.1 - 0.31 11.1 3.4 14 5.7 2.6 2.2 2 0 0 2 2 2 0 Mut7-C RNAse domain Zn_ribbon_SprT PF17283.2 EGG00174.1 - 1.3 9.0 7.8 1.1 9.2 0.3 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-nanos PF05741.13 EGG00174.1 - 3.4 8.0 10.0 11 6.4 1.5 3.0 3 0 0 3 3 3 0 Nanos RNA binding domain DnaJ_CXXCXGXG PF00684.19 EGG00174.1 - 8.8 6.8 17.0 8 6.9 13.3 2.6 2 1 0 2 2 2 0 DnaJ central domain Sec61_beta PF03911.16 EGG00175.1 - 1.5e-16 60.2 0.0 1.8e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Sec61beta family ING PF12998.7 EGG00176.1 - 5.5e-17 62.2 0.4 5.5e-17 62.2 0.4 2.5 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Cas_Csn2 PF09711.10 EGG00176.1 - 1.4 8.5 11.2 0.41 10.3 7.5 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csn2) Aminotran_1_2 PF00155.21 EGG00177.1 - 1.8e-55 188.6 0.0 2.3e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGG00177.1 - 8.8e-06 25.2 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pollen_allerg_1 PF01357.21 EGG00179.1 - 0.00012 22.0 0.5 0.00012 22.0 0.5 2.0 2 0 0 2 2 2 1 Pollen allergen Ribosomal_L32e PF01655.18 EGG00181.1 - 1.3e-50 170.4 0.3 1.5e-50 170.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 PLA2_B PF01735.18 EGG00182.1 - 4.3e-56 190.3 8.0 2.6e-39 135.0 4.3 4.0 2 2 1 3 3 3 3 Lysophospholipase catalytic domain DUF2841 PF11001.8 EGG00183.1 - 6.6e-39 132.8 0.2 1.5e-38 131.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) UMP1 PF05348.11 EGG00185.1 - 5.1e-30 104.1 0.1 6.1e-30 103.9 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 NARP1 PF12569.8 EGG00186.1 - 7.3e-114 381.5 3.5 1.4e-113 380.6 3.5 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 EGG00186.1 - 4.3e-12 46.4 13.8 0.0035 17.8 1.1 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGG00186.1 - 8.4e-07 29.3 18.1 0.036 14.9 1.2 6.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG00186.1 - 3.7e-06 26.6 13.6 0.074 13.2 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG00186.1 - 9.5e-06 25.2 2.3 0.0059 16.3 0.4 3.3 3 1 0 3 3 3 2 TPR repeat TPR_1 PF00515.28 EGG00186.1 - 0.00015 21.5 9.5 0.52 10.2 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG00186.1 - 0.0002 22.0 19.2 2.4 8.9 2.2 6.3 6 1 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG00186.1 - 0.0052 17.0 1.3 2.9 8.2 0.2 4.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGG00186.1 - 0.012 15.9 3.1 2.8 8.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGG00186.1 - 0.012 15.8 8.5 13 6.3 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGG00186.1 - 0.017 15.3 12.8 0.047 13.8 0.4 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat FKBP_N PF01346.18 EGG00186.1 - 0.02 15.8 0.1 1.2 10.1 0.0 2.9 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Ras_bdg_2 PF14847.6 EGG00186.1 - 0.045 14.1 0.5 0.21 12.0 0.0 2.3 2 1 0 2 2 1 0 Ras-binding domain of Byr2 TPR_7 PF13176.6 EGG00186.1 - 1 9.5 15.2 12 6.2 0.2 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG00186.1 - 6.1 7.2 22.2 25 5.2 1.5 6.6 6 1 1 7 7 7 0 Tetratricopeptide repeat NARP1 PF12569.8 EGG00187.1 - 0.042 12.8 0.0 0.042 12.8 0.0 1.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Pkinase PF00069.25 EGG00188.1 - 3.5e-32 111.8 0.0 3.8e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG00188.1 - 8.3e-21 74.4 0.0 9.1e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGG00188.1 - 2e-09 37.1 0.0 2.6e-09 36.8 0.0 1.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGG00188.1 - 0.017 14.7 0.0 0.021 14.4 0.0 1.3 1 1 0 1 1 1 0 Choline/ethanolamine kinase PufQ PF05398.11 EGG00191.1 - 0.053 13.7 0.2 0.13 12.4 0.2 1.7 1 0 0 1 1 1 0 PufQ cytochrome subunit zf-MIZ PF02891.20 EGG00192.1 - 2.4e-13 49.6 0.0 5e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EGG00192.1 - 0.0002 21.1 0.0 0.00059 19.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit NOA36 PF06524.12 EGG00192.1 - 0.2 11.0 3.5 0.29 10.4 3.5 1.3 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 EGG00192.1 - 2.2 6.7 5.6 4.1 5.8 5.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ABC_membrane_2 PF06472.15 EGG00193.1 - 6.5e-91 304.5 8.3 8.3e-91 304.1 8.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGG00193.1 - 6.8e-15 55.8 0.0 1.8e-14 54.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter RuvB_N PF05496.12 EGG00193.1 - 0.0048 16.7 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain SMC_N PF02463.19 EGG00193.1 - 0.023 14.1 0.0 5.9 6.3 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGG00193.1 - 0.027 14.9 0.1 0.06 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EGG00193.1 - 0.027 14.2 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EGG00193.1 - 0.028 14.3 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGG00193.1 - 0.033 14.7 0.0 0.069 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGG00193.1 - 0.034 14.6 0.1 0.066 13.6 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGG00193.1 - 0.068 13.7 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGG00193.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGG00193.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TMEM208_SND2 PF05620.11 EGG00194.1 - 1.4 8.6 4.5 4.7 7.0 4.5 1.9 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Sad1_UNC PF07738.13 EGG00195.1 - 6.3e-23 81.2 0.0 7.9e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Ribophorin_I PF04597.14 EGG00196.1 - 9.8e-106 354.6 0.0 1.1e-105 354.4 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I HMG-CoA_red PF00368.18 EGG00197.1 - 3.6e-138 460.6 3.6 4.5e-138 460.2 3.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 EGG00197.1 - 2.2e-16 60.0 1.1 6.1e-16 58.6 1.1 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EGG00197.1 - 1.9e-10 39.6 3.4 1.2e-09 36.9 1.5 2.2 2 0 0 2 2 2 2 Patched family PAPA-1 PF04795.12 EGG00198.1 - 1.4e-19 70.7 1.4 1.4e-19 70.7 1.4 3.0 2 1 0 2 2 2 1 PAPA-1-like conserved region efThoc1 PF11957.8 EGG00202.1 - 3.8e-85 286.4 0.1 2.3e-84 283.8 0.1 2.1 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Myosin_head PF00063.21 EGG00203.1 - 1.1e-51 175.9 0.1 1.4e-51 175.6 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EGG00203.1 - 2.7e-10 39.9 4.0 1e-07 31.7 1.2 2.3 2 0 0 2 2 2 2 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 EGG00203.1 - 0.0087 16.3 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EGG00203.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EGG00203.1 - 0.18 12.2 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EGG00203.1 - 0.28 10.9 1.1 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain PhoLip_ATPase_C PF16212.5 EGG00206.1 - 2e-71 240.7 31.9 2e-71 240.7 31.9 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGG00206.1 - 5.6e-22 77.2 1.3 1.5e-21 75.8 1.3 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGG00206.1 - 3.6e-14 53.6 0.9 9.4e-06 26.1 0.1 3.7 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG00206.1 - 5.6e-12 45.6 0.0 2e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGG00206.1 - 7.5e-06 25.6 0.2 7.5e-06 25.6 0.2 2.8 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGG00206.1 - 0.00015 21.6 0.1 0.0087 15.8 0.1 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG00206.1 - 0.0055 17.1 0.0 0.42 11.0 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGG00206.1 - 0.018 15.1 0.1 0.044 13.9 0.1 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Trp_halogenase PF04820.14 EGG00207.1 - 0.074 11.9 0.6 0.11 11.4 0.6 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Tetraspanin PF00335.20 EGG00208.1 - 0.43 10.3 10.8 1.9 8.1 10.8 2.0 1 1 0 1 1 1 0 Tetraspanin family NPCC PF08058.11 EGG00209.1 - 0.14 12.2 0.8 0.3 11.2 0.8 1.5 1 0 0 1 1 1 0 Nuclear pore complex component Tetraspanin PF00335.20 EGG00209.1 - 0.57 9.9 8.6 3.1 7.5 8.6 2.2 1 1 0 1 1 1 0 Tetraspanin family Med6 PF04934.14 EGG00211.1 - 1.7e-36 124.9 0.0 2.9e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Tom5 PF10642.9 EGG00211.1 - 0.11 12.5 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase DnaJ PF00226.31 EGG00212.1 - 5.2e-14 52.1 0.1 2.1e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 EGG00212.1 - 7.2e-05 22.6 0.7 1.5 9.1 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG00212.1 - 0.00095 18.9 0.2 6.9 6.7 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG00212.1 - 0.004 17.7 5.0 0.06 14.0 0.1 4.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG00212.1 - 0.072 13.3 0.2 39 4.8 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DHHA2 PF02833.14 EGG00213.1 - 0.083 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 DHHA2 domain Alpha_kinase PF02816.18 EGG00215.1 - 9.5e-15 55.2 0.3 1.4e-14 54.7 0.3 1.2 1 0 0 1 1 1 1 Alpha-kinase family CxC1 PF18802.1 EGG00216.1 - 0.051 13.7 0.8 0.1 12.8 0.8 1.5 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases OB_NTP_bind PF07717.16 EGG00219.1 - 1.1e-18 67.3 0.0 1.7e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold YvbH_ext PF11724.8 EGG00220.1 - 0.019 15.3 0.0 0.063 13.6 0.0 1.9 1 0 0 1 1 1 0 YvbH-like oligomerisation region SKG6 PF08693.10 EGG00222.1 - 0.11 11.9 0.8 0.2 11.1 0.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mid2 PF04478.12 EGG00222.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TFIIA PF03153.13 EGG00222.1 - 6.3 6.7 16.5 8.3 6.3 16.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit M PF02370.16 EGG00223.1 - 0.59 10.9 2.6 1.5 9.6 2.6 1.7 1 0 0 1 1 1 0 M protein repeat Melibiase_2 PF16499.5 EGG00225.1 - 3.5e-34 118.3 0.0 5.8e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EGG00225.1 - 1.5e-11 44.2 1.2 3.1e-11 43.2 1.2 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EGG00225.1 - 7.4e-05 21.9 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Melibiase ECH_2 PF16113.5 EGG00228.1 - 9.9e-112 373.7 0.0 1.3e-111 373.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGG00228.1 - 1.1e-26 93.6 0.2 2.2e-26 92.7 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Thi4 PF01946.17 EGG00230.1 - 8.6e-103 342.6 0.0 1.1e-102 342.3 0.0 1.1 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EGG00230.1 - 5.2e-07 29.8 0.2 1.7e-06 28.1 0.2 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG00230.1 - 6.1e-07 29.3 0.1 9.1e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG00230.1 - 4.5e-06 26.1 0.2 1.2e-05 24.7 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGG00230.1 - 5.2e-05 22.5 0.3 0.00011 21.4 0.3 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGG00230.1 - 0.00021 20.5 0.3 0.00043 19.5 0.4 1.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EGG00230.1 - 0.00074 19.5 0.0 0.0054 16.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EGG00230.1 - 0.0008 18.2 0.2 0.0011 17.7 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EGG00230.1 - 0.0026 17.2 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGG00230.1 - 0.0092 15.3 0.3 0.014 14.7 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGG00230.1 - 0.022 13.6 0.1 0.032 13.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 EGG00230.1 - 0.06 12.4 0.4 0.092 11.8 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 EGG00230.1 - 0.092 11.9 0.0 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EGG00230.1 - 0.14 11.4 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain V-set_CD47 PF08204.11 EGG00230.1 - 0.19 11.7 0.1 0.33 10.9 0.1 1.3 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Pribosyltran_N PF13793.6 EGG00232.1 - 5.9e-41 139.1 0.2 3.7e-39 133.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGG00232.1 - 8.4e-39 133.5 4.9 1.1e-32 113.5 0.8 2.8 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGG00232.1 - 6.7e-16 58.2 0.7 2.2e-15 56.6 0.6 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGG00232.1 - 0.012 15.0 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Peptidase_M48 PF01435.18 EGG00234.1 - 3.9e-14 52.9 0.2 4.9e-14 52.6 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M48 BcrAD_BadFG PF01869.20 EGG00235.1 - 1.1e-11 44.7 0.0 8.2e-10 38.6 0.0 2.8 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family RBD PF02196.15 EGG00235.1 - 0.13 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Raf-like Ras-binding domain MoaE PF02391.17 EGG00237.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 MoaE protein DUF2018 PF09442.10 EGG00238.1 - 0.1 13.6 0.0 0.19 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) MCM_bind PF09739.9 EGG00239.1 - 1.8e-70 238.0 7.7 9.3e-55 186.2 3.8 2.2 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor MCM_lid PF17855.1 EGG00239.1 - 0.092 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 MCM AAA-lid domain DrrA_P4M PF14860.6 EGG00240.1 - 0.039 13.8 0.3 0.099 12.5 0.3 1.8 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain DNA_ligase_A_N PF04675.14 EGG00241.1 - 1.1e-09 38.8 1.2 7.7e-09 36.1 0.0 2.6 2 1 0 2 2 2 1 DNA ligase N terminus DUF4813 PF16072.5 EGG00241.1 - 0.23 11.1 6.6 0.34 10.6 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) PolyA_pol PF01743.20 EGG00242.1 - 3.9e-08 33.8 0.2 4.5e-08 33.6 0.2 1.1 1 0 0 1 1 1 1 Poly A polymerase head domain RNA_pol_Rpb2_7 PF04560.20 EGG00243.1 - 1.2e-08 35.2 0.1 1.4e-08 35.0 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 AhpC-TSA_2 PF13911.6 EGG00244.1 - 6.8e-12 45.5 0.0 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGG00244.1 - 0.0002 21.3 0.0 0.00039 20.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family NDK PF00334.19 EGG00245.1 - 6.4e-54 181.6 0.0 7.2e-54 181.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PRP4 PF08799.11 EGG00246.1 - 0.042 13.4 0.6 0.071 12.7 0.6 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like NAM-associated PF14303.6 EGG00247.1 - 7.3e-11 43.1 0.3 2.3e-10 41.5 0.3 1.7 1 1 0 1 1 1 1 No apical meristem-associated C-terminal domain KKLCAg1 PF15204.6 EGG00248.1 - 0.084 13.0 2.0 0.18 12.0 2.0 1.5 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 Cyclin_N PF00134.23 EGG00250.1 - 1e-08 35.0 0.0 1.7e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF4630 PF15443.6 EGG00250.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) LrgB PF04172.16 EGG00252.1 - 2.5e-39 135.0 8.4 2.5e-39 135.0 8.4 2.0 2 0 0 2 2 2 1 LrgB-like family TMEM174 PF15029.6 EGG00252.1 - 0.37 10.5 1.1 0.74 9.5 1.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 174 MccV PF17508.2 EGG00252.1 - 0.37 11.4 2.4 2.2 8.9 0.2 2.4 2 0 0 2 2 2 0 Microcin V bacteriocin Peptidase_M16_M PF16187.5 EGG00253.1 - 2.6e-78 263.2 1.6 5.9e-78 262.0 0.0 2.3 3 0 0 3 3 3 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EGG00253.1 - 2.1e-39 134.9 0.0 2.1e-39 134.9 0.0 3.2 4 1 1 5 5 5 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGG00253.1 - 7.4e-37 127.1 0.4 1.1e-21 77.7 0.0 4.0 4 0 0 4 4 4 2 Peptidase M16 inactive domain zf-C2H2_2 PF12756.7 EGG00255.1 - 2.9e-26 91.7 11.0 3e-20 72.4 2.9 4.1 3 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGG00255.1 - 8.4e-08 32.3 8.8 0.00019 21.6 0.4 4.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG00255.1 - 0.0012 19.1 0.5 0.0012 19.1 0.5 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGG00255.1 - 0.028 15.3 9.9 5.7 8.0 0.1 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGG00255.1 - 2.8 8.5 7.0 19 5.9 0.1 3.9 3 0 0 3 3 3 0 Zinc-finger double domain Cellulase PF00150.18 EGG00256.1 - 0.00066 19.2 0.2 0.0026 17.2 0.2 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.8 EGG00256.1 - 0.029 14.0 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase catalytic core SpoIIE PF07228.12 EGG00257.1 - 1.7e-07 31.3 0.0 3.7e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EGG00257.1 - 0.004 16.8 0.1 0.38 10.3 0.3 2.3 1 1 1 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGG00257.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C DUF5641 PF18701.1 EGG00257.1 - 0.025 14.7 0.7 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5641) Vault_4 PF17796.1 EGG00257.1 - 0.12 12.5 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Major Vault Protein repeat domain YvbH_ext PF11724.8 EGG00257.1 - 2.1 8.7 4.4 7.8 6.9 0.1 2.7 1 1 1 2 2 2 0 YvbH-like oligomerisation region TruD PF01142.18 EGG00259.1 - 9.2e-05 21.4 0.0 9.2e-05 21.4 0.0 1.0 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Cu-oxidase_2 PF07731.14 EGG00260.1 - 7.9e-38 129.3 0.6 1.4e-30 105.8 0.0 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGG00260.1 - 2.9e-36 124.1 7.9 1.3e-35 121.9 1.1 3.6 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 EGG00260.1 - 7.7e-22 78.1 3.8 1.2e-20 74.2 0.0 3.4 4 0 0 4 4 4 1 Multicopper oxidase DUF3439 PF11921.8 EGG00260.1 - 0.11 12.5 2.6 0.35 10.8 2.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_M24 PF00557.24 EGG00263.1 - 5.3e-49 166.7 0.0 6.7e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EGG00263.1 - 1.5e-14 54.0 9.7 3.3e-14 52.9 9.7 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EGG00263.1 - 0.0013 18.8 6.4 0.0036 17.4 6.4 1.7 1 0 0 1 1 1 1 MYND finger Cript PF10235.9 EGG00263.1 - 0.091 13.3 1.7 0.2 12.2 1.7 1.5 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-HIT PF04438.16 EGG00263.1 - 4 7.4 10.1 0.95 9.4 6.4 1.9 2 0 0 2 2 2 0 HIT zinc finger HDV_ag PF01517.18 EGG00264.1 - 2.2 8.1 6.8 3.9 7.2 6.8 1.3 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen PhoLip_ATPase_C PF16212.5 EGG00267.1 - 8.7e-73 245.1 27.5 1.8e-72 244.1 27.5 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGG00267.1 - 4.2e-24 84.0 0.5 9.9e-24 82.8 0.5 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGG00267.1 - 4.1e-14 53.4 0.2 4.2e-07 30.5 0.0 3.7 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG00267.1 - 3.4e-10 39.9 0.0 1.3e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGG00267.1 - 4.7e-07 29.8 0.1 0.0012 18.7 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGG00267.1 - 1e-05 25.1 2.0 3.8e-05 23.3 0.0 2.8 2 1 0 2 2 2 1 E1-E2 ATPase His_Phos_1 PF00300.22 EGG00269.1 - 1.6e-31 109.6 0.1 1.4e-30 106.5 0.0 2.3 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Fungal_trans PF04082.18 EGG00271.1 - 7.1e-14 51.5 0.4 7.1e-14 51.5 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGG00271.1 - 5.2e-08 32.9 7.1 5.2e-08 32.9 7.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_polI_A34 PF08208.11 EGG00272.1 - 8e-10 39.2 9.8 2.2e-09 37.7 9.8 1.8 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Thiolase_N PF00108.23 EGG00276.1 - 5.3e-67 225.9 0.1 1.5e-66 224.4 0.1 1.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGG00276.1 - 2.4e-43 146.7 0.0 5e-43 145.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGG00276.1 - 0.03 13.9 0.3 0.08 12.5 0.2 1.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Septin PF00735.18 EGG00277.1 - 3.5e-113 377.6 1.5 4.2e-113 377.3 1.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGG00277.1 - 3.4e-09 36.8 0.3 8.2e-09 35.6 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGG00277.1 - 1e-06 28.3 0.1 2e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 EGG00277.1 - 3.4e-06 26.7 0.9 4.5e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGG00277.1 - 5e-06 26.5 0.4 3.8e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGG00277.1 - 3.2e-05 24.0 0.6 0.046 13.8 0.2 2.4 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 EGG00277.1 - 0.00044 19.5 0.1 0.00075 18.8 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 EGG00277.1 - 0.00079 19.9 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.12 EGG00277.1 - 0.0012 18.2 0.4 0.0045 16.4 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 EGG00277.1 - 0.0016 17.9 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Roc PF08477.13 EGG00277.1 - 0.002 18.3 0.1 0.0045 17.2 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EGG00277.1 - 0.0027 17.2 0.2 0.018 14.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 EGG00277.1 - 0.0037 17.7 0.0 0.015 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 EGG00277.1 - 0.0078 15.3 0.1 0.016 14.3 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGG00277.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGG00277.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 EGG00277.1 - 0.041 12.9 0.0 0.083 11.9 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) RuvB_N PF05496.12 EGG00277.1 - 0.045 13.5 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Ras PF00071.22 EGG00277.1 - 0.057 13.0 0.3 0.23 11.0 0.1 2.1 2 0 0 2 2 2 0 Ras family G-alpha PF00503.20 EGG00277.1 - 0.079 12.1 0.3 0.2 10.8 0.3 1.7 1 1 0 1 1 1 0 G-protein alpha subunit CLASP_N PF12348.8 EGG00278.1 - 7e-23 81.4 9.1 1.4e-08 34.6 0.0 5.6 6 0 0 6 6 6 4 CLASP N terminal HEAT PF02985.22 EGG00278.1 - 1.2e-11 43.9 15.7 2.1 8.8 0.0 10.6 11 0 0 11 11 10 4 HEAT repeat Cnd1 PF12717.7 EGG00278.1 - 5.6e-09 36.2 1.5 0.61 10.1 0.0 6.5 6 1 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGG00278.1 - 1.6e-07 31.6 15.5 0.026 14.9 0.1 9.0 7 1 2 9 9 8 1 HEAT repeats DCB PF16213.5 EGG00278.1 - 0.00032 20.4 0.1 0.013 15.2 0.0 3.3 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 V-ATPase_H_C PF11698.8 EGG00278.1 - 0.0011 19.1 0.2 9.5 6.4 0.1 4.5 3 0 0 3 3 3 1 V-ATPase subunit H Dopey_N PF04118.14 EGG00278.1 - 0.0019 17.4 0.3 0.84 8.7 0.0 3.4 4 0 0 4 4 4 2 Dopey, N-terminal Adaptin_N PF01602.20 EGG00278.1 - 0.014 14.0 6.8 0.91 8.0 0.2 5.0 6 0 0 6 6 6 0 Adaptin N terminal region Proteasom_PSMB PF10508.9 EGG00278.1 - 0.016 13.7 0.1 0.016 13.7 0.1 3.0 4 1 0 4 4 4 0 Proteasome non-ATPase 26S subunit MMS19_N PF14500.6 EGG00278.1 - 0.016 14.8 7.5 2.7 7.5 0.0 5.5 6 0 0 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II VHS PF00790.19 EGG00278.1 - 0.057 13.3 2.8 16 5.3 0.0 4.5 5 0 0 5 5 5 0 VHS domain HEAT_EZ PF13513.6 EGG00278.1 - 0.15 12.6 10.5 9 6.9 0.2 6.2 6 0 0 6 6 6 0 HEAT-like repeat SPATA25 PF15218.6 EGG00279.1 - 0.079 12.7 0.0 0.095 12.4 0.0 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 Rhodanese PF00581.20 EGG00281.1 - 4.6e-20 72.1 0.0 1.1e-09 38.7 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain RINGv PF12906.7 EGG00282.1 - 0.036 14.2 0.2 0.074 13.2 0.2 1.5 1 0 0 1 1 1 0 RING-variant domain BRF1 PF07741.13 EGG00283.1 - 0.14 12.5 2.7 0.85 10.0 2.7 2.3 1 1 0 1 1 1 0 Brf1-like TBP-binding domain SRP72 PF08492.12 EGG00283.1 - 0.54 10.7 8.4 0.83 10.1 0.3 2.7 3 0 0 3 3 3 0 SRP72 RNA-binding domain CwfJ_C_1 PF04677.15 EGG00284.1 - 4.4e-30 104.0 0.0 8.2e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 EGG00284.1 - 1.2e-20 73.0 16.4 1.9e-10 40.4 5.0 2.6 2 0 0 2 2 2 2 Zinc knuckle CwfJ_C_2 PF04676.14 EGG00284.1 - 2.2e-09 38.1 0.1 4.6e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 EGG00284.1 - 4.5e-07 29.7 4.8 0.0087 16.1 0.5 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EGG00284.1 - 0.039 13.7 3.3 0.85 9.4 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGG00284.1 - 0.11 12.5 5.3 0.12 12.4 0.7 2.4 1 1 1 2 2 2 0 Zinc knuckle Dus PF01207.17 EGG00285.1 - 8.6e-53 179.4 0.0 1.3e-52 178.9 0.0 1.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-C2H2 PF00096.26 EGG00286.1 - 5.6e-10 39.1 11.1 3.7e-07 30.2 2.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGG00286.1 - 2.2e-08 33.9 4.8 6.1e-05 22.9 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGG00286.1 - 1.3e-07 31.9 10.8 7.8e-05 23.2 1.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGG00286.1 - 0.00027 21.1 4.8 0.0037 17.5 0.2 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EGG00286.1 - 0.0037 17.5 2.3 0.0037 17.5 2.3 2.0 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 EGG00286.1 - 0.0068 16.8 5.6 1 9.8 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EGG00286.1 - 0.0083 16.5 13.2 0.21 12.1 1.1 2.8 3 0 0 3 3 3 2 Zinc-finger double domain Zn-C2H2_12 PF18112.1 EGG00286.1 - 0.024 15.1 1.3 0.36 11.3 0.1 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain BolA PF01722.18 EGG00286.1 - 0.1 12.9 0.0 0.61 10.4 0.0 2.1 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_11 PF16622.5 EGG00286.1 - 0.11 12.2 4.9 3 7.7 1.8 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF2256 PF10013.9 EGG00286.1 - 0.31 11.2 3.5 1.3 9.2 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE PF01363.21 EGG00286.1 - 1.2 9.4 10.0 0.45 10.7 7.2 1.8 2 0 0 2 2 2 0 FYVE zinc finger zf-C2HC_2 PF13913.6 EGG00286.1 - 1.2 9.1 12.3 0.12 12.4 3.1 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type SF3a60_bindingd PF12108.8 EGG00287.1 - 0.13 12.2 0.2 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain CBM_X2 PF03442.14 EGG00288.1 - 0.1 12.7 0.2 0.46 10.6 0.1 2.0 1 1 1 2 2 2 0 Carbohydrate binding domain X2 OTU PF02338.19 EGG00290.1 - 1.2e-12 48.5 0.1 5.3e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGG00290.1 - 0.036 13.5 3.5 4.7 6.6 0.0 3.2 4 0 0 4 4 4 0 Peptidase C65 Otubain Lectin_N PF03954.14 EGG00290.1 - 1.2 8.9 3.7 3.1 7.6 3.7 1.7 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain TF_Zn_Ribbon PF08271.12 EGG00291.1 - 0.045 13.3 0.1 0.09 12.3 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding THOC7 PF05615.13 EGG00292.1 - 1.2e-08 35.3 8.4 1.2e-08 35.3 8.4 2.7 2 1 0 3 3 3 1 Tho complex subunit 7 PAM2 PF07145.15 EGG00292.1 - 0.096 12.4 0.2 0.24 11.2 0.2 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region MFS_1 PF07690.16 EGG00293.1 - 7.8e-09 34.9 26.1 1.2e-07 31.0 26.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 EGG00294.1 - 4e-22 78.6 28.3 5.2e-22 78.2 28.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF373 PF04123.13 EGG00294.1 - 0.44 9.9 5.1 0.29 10.5 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Vps51 PF08700.11 EGG00295.1 - 2.5e-12 46.7 1.4 4.2e-12 46.0 0.2 2.0 2 0 0 2 2 2 1 Vps51/Vps67 Leo1 PF04004.13 EGG00295.1 - 0.073 12.9 0.8 5.7 6.8 0.1 2.7 3 0 0 3 3 3 0 Leo1-like protein p450 PF00067.22 EGG00296.1 - 1.6e-43 149.1 0.0 2.6e-15 56.1 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 GCV_T_C PF08669.11 EGG00296.1 - 0.063 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Smr PF01713.21 EGG00297.1 - 2.8e-07 30.8 0.0 6.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 EGG00297.1 - 0.0015 18.9 6.7 0.0039 17.5 6.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) YycH PF07435.11 EGG00297.1 - 0.055 12.4 0.7 0.25 10.3 0.1 2.2 2 1 0 2 2 2 0 YycH protein CENP-Q PF13094.6 EGG00298.1 - 0.013 15.7 0.1 0.013 15.7 0.1 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Cep57_MT_bd PF06657.13 EGG00298.1 - 0.017 15.6 1.0 0.024 15.1 0.3 1.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FAR1 PF03101.15 EGG00299.1 - 3.2e-09 37.4 0.0 6.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 EGG00299.1 - 4.3e-05 23.9 0.4 4.3e-05 23.9 0.4 1.9 2 0 0 2 2 2 1 Transcription factor AFT Helicase_C_4 PF13871.6 EGG00299.1 - 0.036 13.7 0.1 0.053 13.2 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue NAM-associated PF14303.6 EGG00302.1 - 0.48 11.1 2.5 0.74 10.5 2.5 1.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Retrotran_gag_2 PF14223.6 EGG00303.1 - 0.0067 16.1 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF249 PF03158.13 EGG00303.1 - 0.042 13.5 0.2 0.07 12.8 0.2 1.3 1 0 0 1 1 1 0 Multigene family 530 protein F-box-like PF12937.7 EGG00304.1 - 0.009 15.9 1.2 0.05 13.5 1.2 2.3 1 1 0 1 1 1 1 F-box-like DUF3368 PF11848.8 EGG00304.1 - 0.033 14.0 0.0 7.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) HAGH_C PF16123.5 EGG00305.1 - 0.043 14.3 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus LETM1 PF07766.13 EGG00307.1 - 3.2e-103 344.7 5.6 3.2e-103 344.7 5.6 2.4 2 1 1 3 3 3 1 LETM1-like protein EF-hand_8 PF13833.6 EGG00307.1 - 5.1e-05 23.0 0.2 0.00036 20.3 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 EGG00307.1 - 0.00022 21.6 5.8 0.031 14.7 0.1 4.7 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 EGG00307.1 - 0.026 14.1 2.9 1.9 8.3 0.0 4.0 5 0 0 5 5 5 0 EF hand EF-hand_5 PF13202.6 EGG00307.1 - 0.68 9.5 2.5 24 4.6 0.1 3.6 3 0 0 3 3 3 0 EF hand DUF5530 PF17670.1 EGG00308.1 - 0.071 12.9 0.2 6.6 6.5 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5530) HGTP_anticodon PF03129.20 EGG00310.1 - 1.3e-19 70.1 0.9 2.2e-19 69.4 0.1 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGG00310.1 - 2.2e-12 47.3 0.1 6.1e-12 45.9 0.1 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Retinal PF15449.6 EGG00311.1 - 0.51 8.1 11.0 0.59 7.9 11.0 1.2 1 0 0 1 1 1 0 Retinal protein PRCC PF10253.9 EGG00311.1 - 0.79 10.5 4.0 1.5 9.6 4.0 1.5 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MBOAT_2 PF13813.6 EGG00312.1 - 4e-13 49.4 3.2 4e-13 49.4 3.2 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Bac_export_2 PF01312.19 EGG00312.1 - 0.064 12.4 0.8 0.11 11.6 0.8 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Ctr PF04145.15 EGG00312.1 - 0.094 13.3 0.3 0.19 12.3 0.0 1.8 2 0 0 2 2 2 0 Ctr copper transporter family DUF1751 PF08551.10 EGG00316.1 - 3.1e-23 82.2 2.3 6.8e-23 81.1 2.3 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EGG00316.1 - 0.00019 21.4 10.6 0.00039 20.4 10.6 1.4 1 0 0 1 1 1 1 Rhomboid family Tmemb_9 PF05434.11 EGG00317.1 - 0.076 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 TMEM9 Zn_clus PF00172.18 EGG00319.1 - 0.0002 21.4 11.1 0.0005 20.1 11.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 EGG00319.1 - 2 8.8 7.6 0.59 10.5 4.5 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Ribosomal_S9 PF00380.19 EGG00320.1 - 2.3e-32 112.1 0.1 2.6e-32 111.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ldh_1_C PF02866.18 EGG00321.1 - 2.1e-15 57.1 0.1 2.4e-15 56.9 0.1 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain YABBY PF04690.13 EGG00324.1 - 9e-08 32.8 0.1 1.2e-07 32.5 0.1 1.2 1 0 0 1 1 1 1 YABBY protein HMG_box_2 PF09011.10 EGG00324.1 - 0.054 14.1 0.1 0.08 13.6 0.1 1.3 1 0 0 1 1 1 0 HMG-box domain RRM_1 PF00076.22 EGG00325.1 - 3.6e-40 135.6 1.3 9.6e-18 63.8 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG00325.1 - 0.00096 19.2 0.1 5.3 7.2 0.0 3.7 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EGG00325.1 - 0.002 18.1 0.0 0.2 11.7 0.0 2.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGG00325.1 - 0.12 12.4 0.0 0.94 9.6 0.0 2.2 2 1 0 2 2 2 0 RNA binding motif AAA_8 PF12780.7 EGG00327.1 - 0.19 11.0 0.0 0.49 9.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 AMP-binding PF00501.28 EGG00329.1 - 9.2e-17 60.7 0.0 2.2e-10 39.7 0.0 3.1 2 1 1 3 3 3 3 AMP-binding enzyme PP-binding PF00550.25 EGG00329.1 - 0.00068 19.9 0.0 0.003 17.9 0.0 2.1 1 1 0 1 1 1 1 Phosphopantetheine attachment site HEAT PF02985.22 EGG00330.1 - 7.6e-39 128.4 20.5 0.013 15.7 0.0 12.6 12 0 0 12 12 12 11 HEAT repeat HEAT_2 PF13646.6 EGG00330.1 - 2.5e-32 111.1 13.2 8.2e-10 38.9 0.0 7.0 2 1 6 8 8 8 7 HEAT repeats Cnd1 PF12717.7 EGG00330.1 - 1.3e-13 51.3 0.8 0.002 18.2 0.4 5.2 2 2 2 5 5 5 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGG00330.1 - 3.6e-13 49.9 0.2 0.057 14.0 0.0 7.2 2 1 6 8 8 8 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGG00330.1 - 5.1e-12 46.0 13.2 0.0019 18.7 0.5 7.7 6 2 2 8 8 8 3 HEAT-like repeat Arm PF00514.23 EGG00330.1 - 0.00068 19.6 0.3 1.2 9.3 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EGG00330.1 - 0.0012 17.5 2.4 2.1 6.8 0.0 3.2 1 1 2 3 3 3 2 Adaptin N terminal region MEDS PF14417.6 EGG00330.1 - 0.027 14.3 0.1 0.098 12.5 0.0 2.0 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain IFRD PF05004.13 EGG00330.1 - 0.079 12.1 1.2 7 5.7 0.0 3.4 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) API5 PF05918.11 EGG00330.1 - 0.23 10.2 0.8 22 3.7 0.1 3.4 3 1 1 4 4 4 0 Apoptosis inhibitory protein 5 (API5) RhoGEF PF00621.20 EGG00331.1 - 2.6e-12 47.3 0.1 4.3e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain CPSase_L_D2 PF02786.17 EGG00332.1 - 4.2e-113 376.0 0.5 4.1e-82 274.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.21 EGG00332.1 - 2.4e-47 160.7 0.0 5.5e-47 159.5 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 EGG00332.1 - 2.5e-45 154.6 0.0 4.7e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EGG00332.1 - 9.7e-45 151.5 0.0 2.7e-44 150.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 EGG00332.1 - 4.8e-40 136.7 0.1 1.2e-39 135.4 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EGG00332.1 - 1.6e-31 109.5 0.0 3.3e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EGG00332.1 - 1.9e-18 66.4 0.0 2.2e-17 63.0 0.0 2.6 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EGG00332.1 - 5e-16 58.9 0.4 5.5e-08 32.6 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGG00332.1 - 4.9e-15 55.5 0.1 1.7e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EGG00332.1 - 2.6e-10 40.1 0.1 0.0002 21.1 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 EGG00332.1 - 6.2e-06 26.1 0.1 0.0056 16.5 0.0 2.5 1 1 0 2 2 2 2 Peptidase C26 ATP-grasp_3 PF02655.14 EGG00332.1 - 9.5e-06 25.8 0.3 0.0058 16.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain DUF308 PF03729.13 EGG00333.1 - 0.1 12.9 3.6 0.31 11.4 3.6 1.9 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Spo7 PF03907.13 EGG00334.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Spo7-like protein EOS1 PF12326.8 EGG00335.1 - 0.0078 16.2 1.2 0.0078 16.2 1.2 1.3 1 1 0 1 1 1 1 N-glycosylation protein GPI-anchored PF10342.9 EGG00336.1 - 0.022 15.5 2.4 0.023 15.4 0.2 2.2 2 1 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GDI PF00996.18 EGG00337.1 - 3.6e-159 529.9 0.0 4e-159 529.8 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor ODV-E18 PF10717.9 EGG00339.1 - 0.1 12.5 1.0 3.8 7.5 0.1 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Nas2_N PF18265.1 EGG00341.1 - 3.6e-19 68.5 0.5 6.2e-19 67.7 0.5 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EGG00341.1 - 1.2e-05 25.0 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EGG00341.1 - 2.3e-05 24.6 0.0 5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGG00341.1 - 0.0002 21.7 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DUF3090 PF11290.8 EGG00341.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) Prefoldin_2 PF01920.20 EGG00342.1 - 5.1e-15 55.3 10.6 6e-15 55.1 10.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit FliD_C PF07195.12 EGG00342.1 - 0.0078 15.7 5.3 0.013 14.9 5.3 1.3 1 1 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus Fez1 PF06818.15 EGG00342.1 - 0.014 15.9 5.9 0.017 15.6 5.9 1.1 1 0 0 1 1 1 0 Fez1 Cnn_1N PF07989.11 EGG00342.1 - 0.056 13.6 9.1 0.43 10.8 2.5 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 3-PAP PF12578.8 EGG00342.1 - 0.069 12.9 1.1 0.43 10.3 0.1 2.1 2 0 0 2 2 2 0 Myotubularin-associated protein AAA_15 PF13175.6 EGG00342.1 - 0.086 12.5 6.1 0.1 12.3 6.1 1.0 1 0 0 1 1 1 0 AAA ATPase domain PI3K_P85_iSH2 PF16454.5 EGG00342.1 - 0.088 12.4 9.3 0.22 11.1 9.3 1.6 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc7 PF08317.11 EGG00342.1 - 0.12 11.3 9.3 0.14 11.0 9.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 EGG00342.1 - 0.12 12.8 9.0 0.089 13.2 1.7 2.2 1 1 1 2 2 2 0 Snapin/Pallidin Prefoldin PF02996.17 EGG00342.1 - 0.18 11.7 8.5 0.15 12.0 1.5 2.2 1 1 0 2 2 2 0 Prefoldin subunit FTA4 PF13093.6 EGG00342.1 - 0.2 11.5 7.6 0.48 10.3 7.6 1.6 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HIP1_clath_bdg PF16515.5 EGG00342.1 - 0.28 11.8 10.8 2.2 8.9 2.6 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF465 PF04325.13 EGG00342.1 - 0.63 10.1 8.6 0.64 10.1 2.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF465) DUF4140 PF13600.6 EGG00342.1 - 0.66 10.5 4.3 16 6.0 0.6 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PEP-utilisers_N PF05524.13 EGG00342.1 - 0.69 10.1 6.4 1.7 8.9 1.7 2.1 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal YabA PF06156.13 EGG00342.1 - 0.8 10.4 7.8 2.3 8.9 0.4 2.2 1 1 1 2 2 2 0 Initiation control protein YabA FapA PF03961.13 EGG00342.1 - 1.8 7.1 7.7 8.2 4.9 7.7 1.8 1 1 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 EGG00342.1 - 2.9 7.7 9.1 2.7 7.8 0.8 2.3 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 EGG00342.1 - 3.9 8.2 7.2 2.8 8.6 0.8 2.9 2 2 1 3 3 3 0 SlyX DUF4407 PF14362.6 EGG00342.1 - 4.4 6.6 7.1 4 6.7 0.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) NUP50 PF08911.11 EGG00345.1 - 1e-12 48.5 2.4 1e-12 48.5 2.4 4.8 5 2 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 EGG00345.1 - 1.2e-08 35.2 2.3 1.4e-08 35.0 0.7 1.9 2 0 0 2 2 2 1 RanBP1 domain Nucleoporin_FG PF13634.6 EGG00345.1 - 0.00033 21.4 51.0 0.0015 19.4 18.1 6.6 2 2 1 3 3 3 2 Nucleoporin FG repeat region Rap_GAP PF02145.15 EGG00346.1 - 1.5e-42 145.2 0.0 2.8e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EGG00346.1 - 9.8e-14 51.2 4.6 2.2e-11 43.5 0.2 2.2 2 0 0 2 2 2 2 Tuberin Alpha_kinase PF02816.18 EGG00347.1 - 3e-17 63.4 0.3 5.4e-17 62.5 0.1 1.5 2 0 0 2 2 2 1 Alpha-kinase family Pkinase PF00069.25 EGG00348.1 - 1.2e-59 201.9 0.0 1.4e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG00348.1 - 4.7e-30 104.7 0.0 5.4e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGG00348.1 - 0.0012 18.3 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGG00348.1 - 0.037 13.7 0.0 5.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGG00348.1 - 0.043 12.6 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EGG00348.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Pkinase_C PF00433.24 EGG00348.1 - 0.46 11.2 1.8 0.82 10.4 1.8 1.4 1 0 0 1 1 1 0 Protein kinase C terminal domain Ribosomal_L34e PF01199.18 EGG00349.1 - 6.5e-41 138.5 1.9 9.4e-41 138.0 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 EGG00349.1 - 0.59 10.1 5.7 2.3 8.2 0.6 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain KTI12 PF08433.10 EGG00350.1 - 1.7e-54 185.1 0.0 1.8e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EGG00350.1 - 1.6e-05 25.1 0.0 2.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG00350.1 - 0.0016 18.9 0.0 0.0024 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EGG00350.1 - 0.057 12.7 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DDOST_48kD PF03345.14 EGG00351.1 - 3e-130 434.8 0.0 3.4e-130 434.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Ric8 PF10165.9 EGG00352.1 - 3.3e-38 131.9 1.5 4e-38 131.6 1.5 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn NopRA1 PF16201.5 EGG00352.1 - 0.0029 17.2 0.8 0.0091 15.6 0.2 2.1 2 1 1 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Ric8 PF10165.9 EGG00353.1 - 7.5e-40 137.3 0.0 1e-39 136.9 0.0 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn KDZ PF18758.1 EGG00354.1 - 6.6e-20 71.7 0.9 1.1e-19 71.0 0.9 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Myosin_head PF00063.21 EGG00356.1 - 2.4e-23 82.3 0.0 2.7e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) DHC_N2 PF08393.13 EGG00357.1 - 3e-33 115.5 9.1 8.6e-16 58.0 1.2 3.6 2 1 1 3 3 3 3 Dynein heavy chain, N-terminal region 2 MazG-like PF12643.7 EGG00357.1 - 0.068 13.4 0.1 0.4 11.0 0.0 2.4 2 0 0 2 2 2 0 MazG-like family DUF4363 PF14276.6 EGG00357.1 - 0.075 13.2 3.5 2 8.6 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) AAA_6 PF12774.7 EGG00358.1 - 9.6e-63 212.1 0.3 2.3e-43 148.4 0.0 2.8 1 1 1 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGG00358.1 - 2.4e-08 33.5 0.1 4.9e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 EGG00358.1 - 3.1e-08 33.7 0.0 2.3e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGG00358.1 - 0.039 14.1 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EGG00361.1 - 2.1e-11 43.9 0.0 5.4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG00361.1 - 3.9e-09 36.9 0.0 8.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OrsD PF12013.8 EGG00361.1 - 0.0022 18.4 1.7 0.0037 17.7 0.1 2.3 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D T4SS-DNA_transf PF02534.14 EGG00361.1 - 0.0036 16.1 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer ResIII PF04851.15 EGG00361.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-CCHC_2 PF13696.6 EGG00361.1 - 0.024 14.4 6.9 0.25 11.2 0.4 3.5 3 0 0 3 3 3 0 Zinc knuckle DUF1724 PF08350.10 EGG00361.1 - 0.054 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) DUF883 PF05957.13 EGG00362.1 - 0.094 13.3 2.7 0.59 10.8 0.0 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) PI3_PI4_kinase PF00454.27 EGG00364.1 - 1.9e-31 109.8 0.0 2e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase HTH_38 PF13936.6 EGG00365.1 - 0.0015 18.3 0.1 0.0072 16.1 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain Retrotran_gag_2 PF14223.6 EGG00366.1 - 9.4e-07 28.6 0.5 1.5e-06 27.9 0.5 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type COPI_C PF06957.11 EGG00366.1 - 0.065 12.0 0.0 0.42 9.3 0.0 1.9 1 1 1 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus CxC6 PF18721.1 EGG00367.1 - 4.6e-22 78.1 3.1 1e-21 77.0 3.1 1.6 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 EGG00367.1 - 2.2e-16 60.0 16.1 7.1e-16 58.3 9.1 2.9 2 1 0 2 2 2 1 CxC5 like cysteine cluster associated with KDZ transposases Pex24p PF06398.11 EGG00369.1 - 7.1e-30 104.2 5.5 1.3e-29 103.3 5.5 1.4 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin SAS4 PF15460.6 EGG00370.1 - 0.15 12.1 21.3 0.26 11.4 4.6 3.8 2 1 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 Rad10 PF03834.14 EGG00371.1 - 2e-43 147.1 0.1 3.7e-43 146.2 0.1 1.4 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EGG00371.1 - 5.4e-08 33.3 0.0 1e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EGG00371.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.23 EGG00371.1 - 0.039 13.8 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif MNR PF15718.5 EGG00371.1 - 0.16 10.1 0.0 0.19 9.9 0.0 1.0 1 0 0 1 1 1 0 Protein moonraker Pkinase PF00069.25 EGG00372.1 - 3.5e-17 62.7 0.0 7.6e-08 32.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG00372.1 - 3e-09 36.5 0.1 1.8e-05 24.2 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PITH PF06201.13 EGG00373.1 - 4.5e-38 130.8 0.0 5.4e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain TPR_8 PF13181.6 EGG00374.1 - 2.9e-07 30.2 0.6 0.1 12.8 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG00374.1 - 1.5e-05 24.7 2.4 0.0044 17.0 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG00374.1 - 1.7e-05 25.2 0.0 0.00025 21.5 0.1 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG00374.1 - 5.5e-05 23.7 1.2 0.002 18.8 0.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG00374.1 - 0.00021 21.0 1.0 0.039 13.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG00374.1 - 0.0039 17.5 0.2 0.26 11.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG00374.1 - 0.0049 16.8 2.5 0.26 11.4 0.2 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG00374.1 - 0.007 17.0 0.1 0.06 14.0 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG00374.1 - 0.014 16.0 2.2 0.8 10.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG00374.1 - 0.019 15.2 1.7 0.4 10.9 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGG00374.1 - 0.045 14.1 1.6 0.66 10.3 1.7 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGG00374.1 - 0.059 12.6 0.0 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Nro1 PF12753.7 EGG00374.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Peroxin-13_N PF04088.13 EGG00375.1 - 5.3e-39 133.8 1.1 5.3e-39 133.8 1.1 1.6 2 0 0 2 2 2 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EGG00375.1 - 7.4e-11 41.6 0.1 1.8e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGG00375.1 - 4.2e-10 39.1 0.1 7.4e-10 38.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGG00375.1 - 6.2e-09 35.6 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.14 EGG00375.1 - 0.075 12.6 0.2 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region SurE PF01975.17 EGG00376.1 - 5.4e-41 140.5 0.0 8.1e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE DUF1940 PF09155.10 EGG00376.1 - 0.21 11.7 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) Ion_trans PF00520.31 EGG00377.1 - 0.00013 21.2 6.3 0.00018 20.8 6.3 1.1 1 0 0 1 1 1 1 Ion transport protein GDI PF00996.18 EGG00379.1 - 1.2e-215 716.1 0.0 1.3e-215 715.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Glyco_hydro_18 PF00704.28 EGG00380.1 - 1.3e-59 202.5 0.0 1.4e-59 202.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 EGG00380.1 - 0.048 13.1 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 DUF4849 PF16141.5 EGG00380.1 - 0.19 10.9 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Putative glycoside hydrolase Family 18, chitinase_18 SMC_N PF02463.19 EGG00381.1 - 1.7e-26 93.0 0.0 6.1e-26 91.2 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGG00381.1 - 2.7e-07 31.3 66.8 7.2e-07 29.9 35.1 5.2 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EGG00381.1 - 5.8e-07 29.6 7.5 5.8e-07 29.6 7.5 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EGG00381.1 - 7.1e-05 22.8 6.4 0.0061 16.4 0.2 3.6 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGG00381.1 - 0.0033 17.1 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CENP-F_leu_zip PF10473.9 EGG00381.1 - 0.2 11.7 0.1 0.2 11.7 0.1 7.0 5 2 2 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3006 PF11213.8 EGG00381.1 - 0.31 11.3 3.9 0.3 11.3 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Myosin_tail_1 PF01576.19 EGG00381.1 - 4.1 5.1 63.1 0.086 10.6 22.4 3.0 2 1 1 3 3 3 0 Myosin tail SlyX PF04102.12 EGG00381.1 - 9.5 6.9 30.5 1.2 9.8 0.6 7.0 6 2 1 7 7 7 0 SlyX SMC_N PF02463.19 EGG00382.1 - 7.1e-26 91.0 0.0 2.1e-25 89.5 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGG00382.1 - 9.9e-10 38.7 12.6 9.9e-10 38.7 12.6 3.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EGG00382.1 - 8.3e-09 36.2 57.4 2.1e-08 34.9 30.3 4.5 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGG00382.1 - 2e-06 27.8 4.4 0.069 13.0 3.3 3.8 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGG00382.1 - 7.7e-05 22.4 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Bap31_Bap29_C PF18035.1 EGG00382.1 - 0.014 15.4 0.6 0.014 15.4 0.6 4.5 6 0 0 6 6 6 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF637 PF04830.13 EGG00382.1 - 0.067 13.0 1.4 4.8 7.0 0.5 2.5 2 0 0 2 2 2 0 Possible hemagglutinin (DUF637) AAA_16 PF13191.6 EGG00382.1 - 2.7 8.3 0.0 2.7 8.3 0.0 3.8 3 2 0 3 3 3 0 AAA ATPase domain Tfb4 PF03850.14 EGG00383.1 - 0.017 14.6 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 Fimbrial PF00419.20 EGG00383.1 - 0.16 12.2 4.8 0.23 11.7 4.8 1.3 1 0 0 1 1 1 0 Fimbrial protein zf-GRF PF06839.12 EGG00385.1 - 0.0051 16.9 2.3 0.0085 16.2 2.3 1.3 1 0 0 1 1 1 1 GRF zinc finger SPATA3 PF15662.5 EGG00385.1 - 0.4 11.3 7.2 0.17 12.5 4.2 1.8 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family zinc_ribbon_4 PF13717.6 EGG00385.1 - 1.9 8.4 5.6 7.3 6.6 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain APG12 PF04110.13 EGG00387.1 - 6.8e-34 116.1 0.0 8.6e-34 115.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EGG00387.1 - 4.5e-05 23.6 0.0 5.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Ribosomal_L3 PF00297.22 EGG00388.1 - 2.3e-19 69.6 6.3 2.2e-18 66.4 2.1 2.5 2 1 1 3 3 3 2 Ribosomal protein L3 HrcA_DNA-bdg PF03444.15 EGG00388.1 - 0.041 13.5 0.1 0.072 12.8 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding MMM1 PF10296.9 EGG00389.1 - 4.5e-58 196.9 0.0 2.1e-57 194.7 0.0 1.9 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ATG7_N PF16420.5 EGG00390.1 - 1.3e-80 271.3 0.0 1.7e-80 270.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EGG00390.1 - 5.6e-46 156.9 0.0 1e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EGG00390.1 - 0.024 14.7 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 EGG00390.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ribosomal_L4 PF00573.22 EGG00391.1 - 1.3e-46 158.8 0.0 4.7e-46 156.9 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family SAT PF16073.5 EGG00392.1 - 5.3e-11 42.7 0.0 9e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF2198 PF09964.9 EGG00392.1 - 0.013 15.6 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) ORC6 PF05460.13 EGG00393.1 - 0.16 11.2 10.4 0.16 11.2 10.4 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Cwf_Cwc_15 PF04889.12 EGG00397.1 - 1.2 8.9 24.9 0.11 12.3 8.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Utp14 PF04615.13 EGG00397.1 - 1.4 7.4 26.3 1.9 7.0 26.3 1.0 1 0 0 1 1 1 0 Utp14 protein PfkB PF00294.24 EGG00398.1 - 3.3e-41 141.6 0.1 4.2e-41 141.2 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Nitro_FeMo-Co PF02579.17 EGG00398.1 - 0.034 14.5 0.2 3.8 7.9 0.1 2.4 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Peptidase_M76 PF09768.9 EGG00399.1 - 1e-57 194.6 0.1 1.3e-57 194.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EGG00399.1 - 0.054 13.4 1.7 0.07 13.0 0.3 1.9 1 1 1 2 2 2 0 SprT-like family Peptidase_M91 PF14891.6 EGG00399.1 - 0.1 12.9 0.1 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 Effector protein KH_1 PF00013.29 EGG00400.1 - 6.5e-45 150.8 9.7 8.5e-18 64.0 0.7 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGG00400.1 - 2.9e-15 55.8 8.5 3.2e-05 23.7 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGG00400.1 - 1.3e-07 31.4 2.0 0.36 10.7 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EGG00400.1 - 0.01 15.9 5.4 3.7 7.7 0.1 3.4 3 0 0 3 3 3 0 NusA-like KH domain MOEP19 PF16005.5 EGG00400.1 - 0.027 14.5 0.1 1.8 8.6 0.1 3.0 3 0 0 3 3 3 0 KH-like RNA-binding domain DUF2367 PF10164.9 EGG00400.1 - 5.1 7.6 5.1 41 4.7 1.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) DUF3947 PF13135.6 EGG00400.1 - 8.5 6.6 14.9 0.87 9.8 9.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Phage_holin_7_1 PF16081.5 EGG00401.1 - 0.094 12.9 1.9 0.2 11.9 1.9 1.5 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF3100 PF11299.8 EGG00401.1 - 0.21 10.9 2.8 0.4 10.1 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) NAD_binding_6 PF08030.12 EGG00404.1 - 4.5e-16 59.4 0.0 3.2e-10 40.3 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGG00404.1 - 4.3e-13 49.5 11.3 1.4e-11 44.6 11.3 2.8 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGG00404.1 - 4.4e-08 33.2 0.0 9.5e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EGG00404.1 - 0.12 13.1 0.0 0.95 10.1 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Zn_clus PF00172.18 EGG00405.1 - 2.4e-05 24.4 3.3 3.3e-05 23.9 3.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1071 PF06378.11 EGG00405.1 - 0.34 10.5 1.9 0.38 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1071) TPR_9 PF13371.6 EGG00407.1 - 0.048 13.8 0.1 2.5 8.3 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat CCDC-167 PF15188.6 EGG00407.1 - 0.086 13.2 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2605 PF10792.9 EGG00407.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Cas_CT1975 PF09344.10 EGG00409.1 - 0.0065 16.0 1.4 0.0087 15.6 1.4 1.1 1 0 0 1 1 1 1 CT1975-like protein DUF4238 PF14022.6 EGG00409.1 - 0.15 11.6 1.2 0.24 10.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Terminase_6C PF17289.2 EGG00409.1 - 0.18 11.9 0.9 0.29 11.2 0.9 1.2 1 0 0 1 1 1 0 Terminase RNaseH-like domain zf-C2H2 PF00096.26 EGG00410.1 - 2.4e-10 40.3 5.3 0.00015 22.1 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG00410.1 - 1.3e-05 25.7 8.9 0.0025 18.5 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGG00410.1 - 8.3e-05 22.8 8.2 0.0024 18.2 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EGG00410.1 - 0.0023 18.2 0.1 1.3 9.4 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 EGG00410.1 - 0.068 13.6 6.4 0.94 10.0 0.6 2.7 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 EGG00410.1 - 0.33 11.4 4.3 8.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SNRNP27 PF08648.12 EGG00411.1 - 9.2e-28 96.1 0.2 1.1e-27 95.8 0.2 1.1 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins YL1 PF05764.13 EGG00414.1 - 0.0084 16.3 11.6 0.0084 16.3 11.6 2.1 2 0 0 2 2 2 1 YL1 nuclear protein Nop14 PF04147.12 EGG00414.1 - 0.91 7.7 12.6 1.3 7.2 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EGG00414.1 - 0.94 7.9 5.5 1.2 7.6 5.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.16 EGG00414.1 - 1.2 8.2 4.3 2.1 7.5 4.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GREB1 PF15782.5 EGG00414.1 - 1.3 6.1 2.9 1.6 5.7 2.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DNA_pol_phi PF04931.13 EGG00414.1 - 4.1 5.4 15.6 6.1 4.8 15.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 EGG00414.1 - 4.5 7.1 10.7 8.5 6.2 10.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region GH131_N PF18271.1 EGG00415.1 - 1.7e-24 86.9 0.1 5.8e-24 85.1 0.0 1.7 1 1 1 2 2 2 1 Glycoside hydrolase 131 catalytic N-terminal domain Nuc_sug_transp PF04142.15 EGG00418.1 - 1.3e-94 316.9 11.3 1.7e-94 316.5 11.3 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EGG00418.1 - 2.5e-10 40.1 8.5 4.3e-10 39.3 8.5 1.3 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 EGG00418.1 - 6.6e-05 22.3 2.8 6.6e-05 22.3 2.8 2.2 1 1 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 EGG00418.1 - 0.0004 20.6 6.7 0.0004 20.6 6.7 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 EGG00418.1 - 0.00075 19.2 6.8 0.0015 18.2 6.8 1.5 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter TPT PF03151.16 EGG00418.1 - 0.022 14.1 13.8 0.31 10.3 13.5 2.2 1 1 0 1 1 1 0 Triose-phosphate Transporter family zf-FCS PF06467.14 EGG00418.1 - 0.15 12.0 0.4 0.3 11.1 0.4 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif CRT-like PF08627.10 EGG00418.1 - 0.29 10.1 11.3 0.0069 15.4 4.2 1.9 2 1 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like WGG PF10273.9 EGG00419.1 - 0.029 15.0 0.9 17 6.1 0.1 3.2 2 1 0 3 3 3 0 Pre-rRNA-processing protein TSR2 ACP_PD PF04336.12 EGG00419.1 - 0.18 12.3 1.7 23 5.4 0.0 3.6 4 0 0 4 4 4 0 Acyl carrier protein phosphodiesterase DUF3460 PF11943.8 EGG00420.1 - 0.0093 16.2 0.1 0.03 14.6 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3460) Synaptobrevin PF00957.21 EGG00420.1 - 0.069 12.9 0.4 0.24 11.2 0.4 2.0 1 0 0 1 1 1 0 Synaptobrevin zinc_ribbon_10 PF10058.9 EGG00422.1 - 0.071 12.8 0.2 0.071 12.8 0.2 2.1 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Desulfoferrod_N PF06397.12 EGG00424.1 - 0.096 12.3 3.7 0.3 10.7 0.1 2.5 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-CCHC_2 PF13696.6 EGG00424.1 - 9.3 6.2 9.0 1.8 8.5 0.4 3.1 3 0 0 3 3 3 0 Zinc knuckle EAF PF09816.9 EGG00425.1 - 0.00016 22.1 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DNA_pol_phi PF04931.13 EGG00425.1 - 0.18 9.9 5.9 0.25 9.4 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Polysacc_deac_1 PF01522.21 EGG00426.1 - 2.5e-19 69.4 0.0 4.6e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase LRRC37AB_C PF14914.6 EGG00426.1 - 0.0092 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain CD34_antigen PF06365.12 EGG00426.1 - 0.042 13.4 0.2 0.07 12.7 0.2 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Synaptobrevin PF00957.21 EGG00426.1 - 0.047 13.5 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Synaptobrevin SLAIN PF15301.6 EGG00426.1 - 0.062 12.6 0.3 0.091 12.0 0.3 1.2 1 0 0 1 1 1 0 SLAIN motif-containing family Glycophorin_A PF01102.18 EGG00426.1 - 0.087 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Nuc_sug_transp PF04142.15 EGG00427.1 - 1.5e-93 313.4 16.6 9.4e-83 278.0 10.5 2.0 2 0 0 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.11 EGG00427.1 - 1.4e-06 27.8 12.3 3.1e-06 26.6 12.3 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGG00427.1 - 3e-05 24.2 3.5 3e-05 24.2 3.5 2.8 2 1 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 EGG00427.1 - 0.00035 19.9 18.2 0.00098 18.4 18.2 1.6 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EmrE PF13536.6 EGG00427.1 - 0.00084 19.0 9.0 0.0034 17.0 9.0 2.0 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter TPT PF03151.16 EGG00427.1 - 0.003 17.0 11.5 0.037 13.4 11.6 2.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 EGG00427.1 - 0.095 11.6 10.5 0.0089 15.0 5.6 1.8 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like DUF202 PF02656.15 EGG00427.1 - 1.5 9.3 6.2 0.25 11.8 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Transferase PF02458.15 EGG00428.1 - 0.66 8.6 3.1 0.85 8.2 3.1 1.1 1 0 0 1 1 1 0 Transferase family Xpo1 PF08389.12 EGG00430.1 - 3.1e-18 66.2 0.0 1.3e-17 64.3 0.0 2.1 1 0 0 1 1 1 1 Exportin 1-like protein cobW PF02492.19 EGG00431.1 - 1.9e-46 157.9 7.7 2e-35 121.9 0.7 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGG00431.1 - 3.3e-16 59.0 0.0 4.1e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain ATPase_2 PF01637.18 EGG00431.1 - 0.014 15.3 0.5 0.09 12.7 0.0 2.5 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea GTP_EFTU PF00009.27 EGG00431.1 - 0.015 14.9 2.8 2.4 7.6 0.4 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGG00431.1 - 0.021 14.8 1.1 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 EGG00431.1 - 0.03 14.1 0.4 9.4 5.9 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EGG00431.1 - 0.069 13.5 0.0 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 EGG00431.1 - 0.086 13.0 0.0 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain CPSase_L_D2 PF02786.17 EGG00437.1 - 9.1e-34 116.8 0.2 1.3e-33 116.3 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain HMGL-like PF00682.19 EGG00437.1 - 2.2e-08 34.0 1.1 4e-08 33.1 1.1 1.3 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.19 EGG00437.1 - 0.00014 21.9 0.0 0.00034 20.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain DUF3195 PF11424.8 EGG00440.1 - 0.068 13.2 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) Actin PF00022.19 EGG00446.1 - 0.076 11.6 0.1 0.11 11.1 0.1 1.3 1 0 0 1 1 1 0 Actin Ig_GlcNase PF18368.1 EGG00446.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Exo-beta-D-glucosaminidase Ig-fold domain Citrate_synt PF00285.21 EGG00447.1 - 3.1e-93 312.7 0.0 3.7e-93 312.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Glyco_transf_43 PF03360.16 EGG00449.1 - 9.9e-05 22.3 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 43 TAF8_C PF10406.9 EGG00451.1 - 0.081 13.5 0.9 0.16 12.6 0.9 1.4 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term CSN8_PSD8_EIF3K PF10075.9 EGG00452.1 - 0.025 14.5 0.1 0.047 13.7 0.1 1.3 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Glyco_trans_1_2 PF13524.6 EGG00454.1 - 0.00085 19.7 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 RuBisCo_chap_C PF18087.1 EGG00454.1 - 0.067 12.9 0.0 0.79 9.4 0.0 2.1 2 0 0 2 2 2 0 Rubisco Assembly chaperone C-terminal domain Glyco_transf_43 PF03360.16 EGG00457.1 - 6.7e-12 45.7 0.0 8.3e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 Sulfate_transp PF00916.20 EGG00460.1 - 8.5e-102 340.7 22.3 9.9e-102 340.5 22.3 1.0 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 EGG00460.1 - 0.0032 17.9 2.8 0.0032 17.9 2.8 4.1 3 2 1 4 4 4 1 Molybdate transporter of MFS superfamily 2OG-FeII_Oxy PF03171.20 EGG00461.1 - 6.1e-08 33.1 0.0 1.2e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGG00461.1 - 0.00038 21.2 0.0 0.0006 20.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal HMGL-like PF00682.19 EGG00462.1 - 6.1e-80 268.6 0.2 1.1e-79 267.7 0.1 1.5 2 0 0 2 2 2 1 HMGL-like eRF1_2 PF03464.15 EGG00463.1 - 1.2e-46 158.3 0.1 2.3e-46 157.4 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGG00463.1 - 8.7e-36 122.8 0.0 1.8e-35 121.8 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EGG00463.1 - 7.3e-20 71.3 0.0 1.2e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 EGG00463.1 - 3.7e-10 40.2 0.0 6.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 EGG00463.1 - 2.6e-09 37.5 0.0 5.4e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 Fibrinogen_aC PF12160.8 EGG00465.1 - 0.031 14.1 4.0 0.071 13.0 4.0 1.7 1 1 0 1 1 1 0 Fibrinogen alpha C domain GEMIN8 PF15348.6 EGG00465.1 - 0.13 12.6 7.2 0.021 15.1 4.0 1.4 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Presenilin PF01080.17 EGG00465.1 - 0.23 10.2 5.2 0.27 10.0 5.2 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EGG00465.1 - 0.49 8.5 6.4 0.57 8.3 6.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.13 EGG00465.1 - 0.62 8.8 8.8 0.69 8.6 8.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nucleo_P87 PF07267.11 EGG00465.1 - 0.69 8.7 7.7 0.89 8.3 7.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 EGG00465.1 - 1.4 8.2 10.3 2 7.7 10.3 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4820 PF16091.5 EGG00465.1 - 1.8 7.9 7.6 3.7 6.9 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PGA2 PF07543.12 EGG00465.1 - 5.2 7.0 15.1 1.2 9.1 8.8 2.0 1 1 1 2 2 2 0 Protein trafficking PGA2 GREB1 PF15782.5 EGG00465.1 - 9.3 3.2 9.7 11 3.0 9.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer KIX_2 PF16987.5 EGG00466.1 - 0.034 14.1 0.1 0.1 12.6 0.1 1.8 1 0 0 1 1 1 0 KIX domain MutS_V PF00488.21 EGG00467.1 - 9.5e-82 273.6 0.5 1.9e-81 272.6 0.5 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGG00467.1 - 8e-36 124.1 0.4 8e-36 124.1 0.4 2.3 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EGG00467.1 - 1e-18 67.4 1.6 1e-18 67.4 1.6 2.6 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.17 EGG00467.1 - 6.7e-15 55.6 0.2 1.3e-12 48.2 0.0 3.6 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 EGG00467.1 - 6.9e-12 45.6 0.0 2.1e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain I AAA_27 PF13514.6 EGG00467.1 - 0.015 14.9 0.1 0.055 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF5494 PF17598.2 EGG00467.1 - 0.23 11.6 0.6 18 5.5 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5494) Baculo_PEP_C PF04513.12 EGG00467.1 - 0.73 9.9 2.9 32 4.5 0.3 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PPR_2 PF13041.6 EGG00468.1 - 0.0042 17.2 1.2 0.11 12.7 0.0 2.8 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.20 EGG00468.1 - 0.079 13.2 1.8 0.37 11.2 0.0 2.7 3 0 0 3 3 3 0 PPR repeat PPR_3 PF13812.6 EGG00468.1 - 0.19 11.8 0.4 0.64 10.1 0.1 2.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain AAA PF00004.29 EGG00469.1 - 9.5e-45 152.3 0.1 5.4e-44 149.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGG00469.1 - 5.9e-08 32.8 0.1 1.6e-07 31.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 EGG00469.1 - 6.6e-08 32.4 0.2 4.7e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EGG00469.1 - 1.1e-07 32.4 0.8 3.7e-05 24.2 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EGG00469.1 - 2.4e-07 31.0 0.0 5.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EGG00469.1 - 6.7e-07 28.7 0.1 7.3e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGG00469.1 - 4.4e-05 23.8 1.1 0.0085 16.4 0.1 2.9 2 1 1 3 3 2 1 AAA domain NTPase_1 PF03266.15 EGG00469.1 - 5.1e-05 23.3 0.1 0.0027 17.7 0.0 2.6 3 0 0 3 3 2 1 NTPase AAA_14 PF13173.6 EGG00469.1 - 0.00022 21.3 0.1 0.0046 17.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 EGG00469.1 - 0.00049 19.9 0.0 0.0014 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 EGG00469.1 - 0.00051 20.6 0.0 0.0026 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EGG00469.1 - 0.00056 19.7 0.0 0.0017 18.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EGG00469.1 - 0.00076 19.5 0.0 0.008 16.2 0.0 2.3 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGG00469.1 - 0.0012 19.2 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGG00469.1 - 0.0021 17.6 0.1 0.013 15.1 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EGG00469.1 - 0.0036 17.7 0.0 0.0098 16.3 0.0 1.7 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.13 EGG00469.1 - 0.0039 16.5 0.0 0.0088 15.3 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_30 PF13604.6 EGG00469.1 - 0.0047 16.7 0.2 0.012 15.4 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EGG00469.1 - 0.0073 16.2 0.1 0.02 14.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EGG00469.1 - 0.0081 15.6 0.0 0.52 9.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 EGG00469.1 - 0.0091 15.4 0.1 0.02 14.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGG00469.1 - 0.0099 16.0 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGG00469.1 - 0.011 15.5 0.1 0.042 13.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 EGG00469.1 - 0.024 14.6 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 EGG00469.1 - 0.025 14.4 0.5 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGG00469.1 - 0.025 14.3 0.2 0.05 13.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGG00469.1 - 0.032 14.2 2.4 0.3 11.0 0.0 2.8 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EGG00469.1 - 0.056 13.0 1.0 0.26 10.8 0.1 2.3 2 1 1 3 3 3 0 AAA domain cobW PF02492.19 EGG00469.1 - 0.063 12.9 0.0 0.32 10.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AFG1_ATPase PF03969.16 EGG00469.1 - 0.071 12.0 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase AAA_19 PF13245.6 EGG00469.1 - 0.12 12.7 0.1 0.4 11.0 0.1 1.8 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 EGG00469.1 - 0.16 11.7 0.3 1.4 8.6 0.0 2.4 3 1 0 3 3 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 EGG00469.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGG00469.1 - 0.17 12.4 5.3 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EGG00469.1 - 0.22 10.6 0.0 0.38 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 EGG00469.1 - 0.23 10.8 1.2 0.58 9.5 0.0 2.1 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.27 EGG00470.1 - 1.7e-49 167.8 0.0 4.9e-27 95.1 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGG00470.1 - 3.9e-17 63.0 1.9 0.0039 17.0 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG00470.1 - 4.1e-15 55.8 0.1 2.1e-06 27.3 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EGG00470.1 - 3.4e-09 36.5 0.6 7e-09 35.5 0.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 EGG00470.1 - 8.5e-08 32.9 0.1 0.024 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EGG00470.1 - 1.2e-07 32.1 0.0 0.00057 20.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EGG00470.1 - 4.4e-07 30.0 3.5 6.8e-05 22.7 0.1 2.6 2 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EGG00470.1 - 3.1e-06 26.8 0.1 0.12 12.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 EGG00470.1 - 4.3e-06 27.3 0.0 0.028 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGG00470.1 - 1.1e-05 25.5 0.0 0.01 15.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EGG00470.1 - 1.6e-05 25.2 0.1 0.11 12.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain 4HB PF17947.1 EGG00470.1 - 4.6e-05 23.4 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Four helical bundle domain RsgA_GTPase PF03193.16 EGG00470.1 - 6.4e-05 22.9 0.0 0.066 13.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGG00470.1 - 7.7e-05 22.8 0.0 0.089 12.8 0.0 2.6 2 0 0 2 2 2 1 Dynamin family RNA_helicase PF00910.22 EGG00470.1 - 0.00012 22.5 0.1 0.93 9.9 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_16 PF13191.6 EGG00470.1 - 0.00012 22.5 0.2 1.1 9.6 0.0 3.3 3 0 0 3 3 2 2 AAA ATPase domain MeaB PF03308.16 EGG00470.1 - 0.00019 20.5 0.2 0.3 10.0 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 EGG00470.1 - 0.00056 19.9 0.2 0.065 13.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 EGG00470.1 - 0.00057 19.9 0.0 0.66 9.9 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 EGG00470.1 - 0.0014 18.8 0.8 2.9 8.1 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_14 PF13173.6 EGG00470.1 - 0.0017 18.4 0.1 0.58 10.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain HEAT PF02985.22 EGG00470.1 - 0.0033 17.5 0.1 2 8.9 0.1 3.8 3 0 0 3 3 2 1 HEAT repeat AAA PF00004.29 EGG00470.1 - 0.0054 17.1 0.0 8.8 6.8 0.0 3.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGG00470.1 - 0.0056 16.4 0.0 2.1 8.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 EGG00470.1 - 0.008 15.4 0.0 0.65 9.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_13 PF13166.6 EGG00470.1 - 0.011 14.4 0.2 0.34 9.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGG00470.1 - 0.021 14.5 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EGG00470.1 - 0.025 14.4 0.3 3.3 7.5 0.0 2.7 3 0 0 3 3 2 0 Deoxynucleoside kinase AAA_27 PF13514.6 EGG00470.1 - 0.03 13.9 0.1 9.8 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EGG00470.1 - 0.037 13.7 0.0 0.67 9.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 EGG00470.1 - 0.038 13.2 0.0 5.4 6.1 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain DUF815 PF05673.13 EGG00470.1 - 0.042 13.0 0.0 10 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 EGG00470.1 - 0.047 13.8 1.0 1.3 9.1 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain Septin PF00735.18 EGG00470.1 - 0.068 12.4 0.0 6.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Septin Roc PF08477.13 EGG00470.1 - 0.11 12.7 0.0 8.1 6.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EGG00470.1 - 0.11 12.2 0.0 16 5.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EGG00470.1 - 0.12 11.9 0.0 7.8 6.0 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EGG00470.1 - 0.12 11.9 0.3 64 3.0 0.0 3.6 4 0 0 4 4 3 0 AAA domain ATP-synt_ab PF00006.25 EGG00470.1 - 0.14 11.8 0.0 1.6 8.3 0.0 2.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 EGG00470.1 - 0.14 12.4 2.2 14 6.0 0.0 3.4 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 EGG00470.1 - 0.14 11.9 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 EGG00470.1 - 0.15 11.9 0.0 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EGG00470.1 - 0.18 11.1 0.7 17 4.7 0.1 2.8 3 0 0 3 3 2 0 Zeta toxin Dysbindin PF04440.16 EGG00471.1 - 0.023 14.8 3.6 0.048 13.8 3.6 1.4 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) Med8 PF10232.9 EGG00471.1 - 0.12 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 CRAL_TRIO PF00650.20 EGG00474.1 - 5.7e-12 45.6 0.0 9.1e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain HlyD_D4 PF16572.5 EGG00475.1 - 0.013 15.4 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB GIT_CC PF16559.5 EGG00475.1 - 0.016 15.0 2.4 0.038 13.8 2.4 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor JIP_LZII PF16471.5 EGG00475.1 - 0.028 14.6 3.4 0.098 12.8 3.4 1.9 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Shugoshin_N PF07558.11 EGG00475.1 - 0.14 12.1 1.2 0.36 10.7 1.2 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Fib_alpha PF08702.10 EGG00475.1 - 0.17 12.1 6.1 0.35 11.1 6.1 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PI_PP_I PF18363.1 EGG00475.1 - 0.5 10.6 2.1 0.37 11.0 0.4 1.6 2 0 0 2 2 1 0 Phosphoinositide phosphatase insertion domain TSC22 PF01166.18 EGG00475.1 - 0.96 9.8 5.7 0.12 12.7 1.0 2.0 2 1 0 2 2 1 0 TSC-22/dip/bun family Cortex-I_coil PF09304.10 EGG00475.1 - 1 9.6 14.4 0.96 9.7 10.0 2.6 2 1 1 3 3 3 0 Cortexillin I, coiled coil Fungal_TACC PF12709.7 EGG00475.1 - 1.4 9.4 8.2 0.18 12.3 3.4 2.1 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins PspB PF06667.12 EGG00475.1 - 2.7 8.1 4.9 7.3 6.7 0.9 2.4 2 0 0 2 2 2 0 Phage shock protein B YabA PF06156.13 EGG00475.1 - 3 8.5 11.7 0.39 11.4 7.2 1.9 2 1 0 2 2 1 0 Initiation control protein YabA HALZ PF02183.18 EGG00475.1 - 5 7.4 7.9 1.2 9.4 2.6 2.7 2 1 0 2 2 2 0 Homeobox associated leucine zipper TMPIT PF07851.13 EGG00475.1 - 5.2 6.2 7.9 7.7 5.7 7.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 EGG00475.1 - 8.6 5.6 21.2 17 4.6 20.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GATA PF00320.27 EGG00476.1 - 8.9e-16 57.2 7.4 1.7e-15 56.3 7.4 1.4 1 0 0 1 1 1 1 GATA zinc finger Nudix_N_2 PF14803.6 EGG00476.1 - 0.0037 17.2 1.6 0.0057 16.5 1.6 1.3 1 0 0 1 1 1 1 Nudix N-terminal ArfGap PF01412.18 EGG00476.1 - 0.004 17.2 0.5 0.0052 16.8 0.5 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DZR PF12773.7 EGG00476.1 - 0.0083 16.1 2.2 0.027 14.5 1.3 2.0 1 1 1 2 2 2 2 Double zinc ribbon zf-NADH-PPase PF09297.11 EGG00476.1 - 0.021 14.5 1.9 0.56 9.9 0.2 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C2H2_3 PF13878.6 EGG00476.1 - 0.11 12.3 1.5 2 8.3 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO RTBV_P46 PF06216.11 EGG00477.1 - 0.098 11.5 0.3 0.15 10.9 0.3 1.3 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein SHR3_chaperone PF08229.11 EGG00478.1 - 3.8e-23 81.5 2.4 1.2e-22 79.8 2.4 1.7 1 1 0 1 1 1 1 ER membrane protein SH3 YwpF PF14183.6 EGG00478.1 - 0.024 14.6 0.3 0.044 13.8 0.3 1.4 1 0 0 1 1 1 0 YwpF-like protein IKI3 PF04762.12 EGG00479.1 - 8.7e-234 778.6 0.0 1.3e-233 778.0 0.0 1.2 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EGG00479.1 - 6.1e-05 23.2 0.0 9.1 6.7 0.0 4.8 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Bacillus_HBL PF05791.11 EGG00479.1 - 1.7 8.4 10.8 12 5.7 2.6 3.3 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Syntaxin PF00804.25 EGG00480.1 - 1.4e-27 96.7 12.1 1.4e-27 96.7 12.1 1.8 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 EGG00480.1 - 1.1e-06 28.5 1.3 1.1e-06 28.5 1.3 2.1 2 0 0 2 2 2 1 SNARE domain MCPsignal PF00015.21 EGG00480.1 - 0.0048 16.7 13.8 0.0085 15.9 4.3 3.0 1 1 2 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Scaffolding_pro PF11418.8 EGG00480.1 - 0.018 15.6 2.2 0.18 12.4 0.1 2.5 2 0 0 2 2 2 0 Phi29 scaffolding protein IFT46_B_C PF12317.8 EGG00480.1 - 0.019 14.7 1.2 1.2 8.8 0.3 2.3 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Vac_Fusion PF02346.16 EGG00480.1 - 0.039 13.6 1.5 0.3 10.7 0.1 2.4 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Fib_alpha PF08702.10 EGG00480.1 - 0.15 12.3 10.4 0.33 11.1 1.2 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Tup_N PF08581.10 EGG00480.1 - 0.21 11.9 9.6 1.8 8.9 1.9 3.6 3 2 0 3 3 3 0 Tup N-terminal Retrotrans_gag PF03732.17 EGG00480.1 - 0.24 11.7 3.7 3.3 8.1 0.3 2.5 2 1 0 2 2 2 0 Retrotransposon gag protein V_ATPase_I PF01496.19 EGG00480.1 - 0.25 9.2 12.0 0.089 10.7 9.0 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF745 PF05335.13 EGG00480.1 - 0.33 10.7 16.0 0.12 12.1 7.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DASH_Dam1 PF08653.10 EGG00480.1 - 0.35 10.7 2.6 19 5.2 0.1 3.3 3 1 0 3 3 3 0 DASH complex subunit Dam1 AATF-Che1 PF13339.6 EGG00480.1 - 0.4 11.4 7.2 0.63 10.7 1.4 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor RPA_C PF08784.11 EGG00480.1 - 0.56 10.9 3.8 0.53 11.0 2.1 1.8 2 0 0 2 2 2 0 Replication protein A C terminal PCRF PF03462.18 EGG00480.1 - 0.78 9.6 14.8 0.16 11.9 4.1 2.8 1 1 2 3 3 3 0 PCRF domain DUF724 PF05266.14 EGG00480.1 - 0.96 9.2 14.9 0.49 10.2 4.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF2203 PF09969.9 EGG00480.1 - 1.1 10.0 15.3 0.19 12.5 4.0 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) SKA1 PF07160.12 EGG00480.1 - 1.2 8.9 10.9 0.062 13.1 1.9 2.3 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF16 PF01519.16 EGG00480.1 - 1.4 9.4 13.2 0.14 12.6 3.0 2.8 2 1 1 3 3 3 0 Protein of unknown function DUF16 BLOC1_2 PF10046.9 EGG00480.1 - 1.6 9.1 8.1 2.8 8.3 1.1 3.5 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 EGG00480.1 - 2.4 8.5 11.9 12 6.3 4.3 3.2 3 0 0 3 3 3 0 ABC transporter C-terminal domain ISG65-75 PF11727.8 EGG00480.1 - 6.6 5.9 14.9 4 6.6 4.9 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF948 PF06103.11 EGG00480.1 - 8.8 6.7 9.6 7.8 6.8 4.2 3.3 3 2 0 3 3 2 0 Bacterial protein of unknown function (DUF948) LIM PF00412.22 EGG00481.1 - 1.5e-12 47.6 23.9 1.9e-11 44.0 3.4 3.8 4 1 0 4 4 4 2 LIM domain zf-CCHC PF00098.23 EGG00482.1 - 1.2e-05 25.1 2.3 1.9e-05 24.5 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle CDC45 PF02724.14 EGG00482.1 - 0.11 10.7 10.3 0.12 10.7 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EGG00482.1 - 0.13 11.7 18.8 0.15 11.4 18.8 1.1 1 0 0 1 1 1 0 SDA1 Trypan_PARP PF05887.11 EGG00482.1 - 1.2 9.2 5.1 1.6 8.7 5.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.12 EGG00482.1 - 1.3 7.2 22.1 1.5 6.9 22.1 1.0 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.23 EGG00484.1 - 1.1e-05 25.2 0.9 2e-05 24.4 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF5003 PF16394.5 EGG00484.1 - 0.15 11.2 3.8 0.22 10.6 3.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5003) DivIC PF04977.15 EGG00484.1 - 5.6 6.8 6.4 28 4.6 0.4 2.7 1 1 1 2 2 2 0 Septum formation initiator Glyco_transf_64 PF09258.10 EGG00485.1 - 0.016 14.5 0.2 0.029 13.6 0.2 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain Acyl-CoA_dh_1 PF00441.24 EGG00489.1 - 1.5e-23 83.7 0.0 2.2e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGG00489.1 - 4e-22 79.0 0.0 7.4e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGG00489.1 - 6.3e-20 71.2 0.0 1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGG00489.1 - 2.4e-05 24.6 0.0 0.00021 21.6 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain VIT1 PF01988.19 EGG00490.1 - 4.2e-61 206.5 1.8 5.7e-61 206.1 1.8 1.2 1 0 0 1 1 1 1 VIT family Egh16-like PF11327.8 EGG00492.1 - 3.9e-25 89.3 0.4 6.4e-25 88.6 0.4 1.2 1 0 0 1 1 1 1 Egh16-like virulence factor Egh16-like PF11327.8 EGG00493.1 - 2.2e-19 70.6 0.0 4.1e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Egh16-like virulence factor Peptidase_C1 PF00112.23 EGG00493.1 - 0.056 13.5 0.6 1.5 8.8 0.2 2.2 2 0 0 2 2 2 0 Papain family cysteine protease Alpha_kinase PF02816.18 EGG00495.1 - 3.1e-11 43.7 4.3 4.9e-11 43.1 4.3 1.3 1 0 0 1 1 1 1 Alpha-kinase family AFT PF08731.11 EGG00496.1 - 3.7e-06 27.3 0.4 7.9e-06 26.2 0.4 1.5 1 0 0 1 1 1 1 Transcription factor AFT FAR1 PF03101.15 EGG00496.1 - 4.8e-05 24.0 0.2 9.2e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain X PF00739.19 EGG00496.1 - 0.0039 17.3 0.1 0.0089 16.2 0.1 1.6 2 0 0 2 2 2 1 Trans-activation protein X Arm PF00514.23 EGG00497.1 - 1.2e-09 37.9 7.2 0.26 11.4 0.0 7.7 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGG00497.1 - 6.1e-08 33.0 1.1 0.00059 20.3 0.4 4.9 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.22 EGG00497.1 - 3.2e-07 30.0 10.9 0.0019 18.3 0.5 7.4 9 0 0 9 9 9 1 HEAT repeat HEAT_2 PF13646.6 EGG00497.1 - 5.3e-07 29.9 2.7 0.84 10.1 0.0 5.6 5 1 1 6 6 6 3 HEAT repeats CTNNBL PF08216.11 EGG00497.1 - 0.0031 17.7 0.1 0.0099 16.0 0.1 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear DUF3361 PF11841.8 EGG00497.1 - 0.048 13.6 7.1 0.084 12.8 0.3 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 EGG00497.1 - 0.19 11.9 6.3 0.46 10.6 0.1 4.1 4 1 0 4 4 4 0 V-ATPase subunit H PCDO_beta_N PF12391.8 EGG00499.1 - 0.015 14.9 0.3 0.047 13.3 0.3 1.9 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal DUF702 PF05142.12 EGG00500.1 - 0.079 13.4 3.3 0.16 12.4 3.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF702) Sel_put PF04328.13 EGG00502.1 - 0.051 13.6 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Selenoprotein, putative DUF5310 PF17237.2 EGG00506.1 - 3.2e-16 58.9 4.3 3.7e-16 58.7 4.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5310) DUF4713 PF15831.5 EGG00506.1 - 0.019 15.4 0.1 0.021 15.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) Glyco_tranf_2_3 PF13641.6 EGG00507.1 - 1.5e-07 31.6 0.0 2.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGG00507.1 - 1.9e-07 30.7 0.0 3.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGG00507.1 - 3.2e-06 27.1 0.0 7.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EGG00507.1 - 0.0047 16.9 7.6 0.0047 16.9 7.6 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF202 PF02656.15 EGG00507.1 - 0.15 12.6 4.9 18 5.9 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF1129 PF06570.11 EGG00507.1 - 0.2 11.1 2.8 1.2 8.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) UreF PF01730.16 EGG00508.1 - 5.2e-19 69.2 0.1 8.5e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 UreF Cwf_Cwc_15 PF04889.12 EGG00510.1 - 0.031 14.0 40.8 0.05 13.3 18.6 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Band_7 PF01145.25 EGG00511.1 - 2.6e-32 112.3 4.2 3.5e-32 111.8 4.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EGG00511.1 - 0.00068 19.4 0.5 0.0011 18.8 0.5 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family GCH_III PF05165.12 EGG00511.1 - 0.025 13.9 0.3 0.036 13.3 0.3 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase III SMODS PF18144.1 EGG00511.1 - 0.042 14.0 0.2 0.17 12.1 0.1 2.0 2 0 0 2 2 2 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Band_7_C PF16200.5 EGG00511.1 - 0.048 13.7 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 C-terminal region of band_7 DUF1542 PF07564.11 EGG00512.1 - 0.088 12.9 0.9 0.18 12.0 0.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) BRCT PF00533.26 EGG00516.1 - 0.071 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain EF-hand_1 PF00036.32 EGG00518.1 - 1.4e-26 90.0 13.4 1.2e-06 27.6 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGG00518.1 - 5.6e-23 81.2 7.5 1.7e-13 50.8 1.5 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGG00518.1 - 1.7e-19 68.0 9.8 0.00013 21.6 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGG00518.1 - 7.8e-17 59.9 14.0 6.7e-05 22.2 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGG00518.1 - 1.9e-13 50.0 12.4 1.1e-05 25.1 1.5 4.3 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGG00518.1 - 2e-06 28.1 0.3 0.054 13.8 0.3 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGG00518.1 - 0.0012 18.7 8.9 0.093 12.7 0.5 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGG00518.1 - 0.0028 18.0 0.2 0.61 10.5 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain Baculo_PEP_C PF04513.12 EGG00520.1 - 0.39 10.8 3.5 0.7 9.9 1.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_S30AE PF02482.19 EGG00520.1 - 0.54 11.1 3.0 26 5.7 0.0 3.2 2 1 1 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF4047 PF13256.6 EGG00520.1 - 4.9 7.4 8.6 0.33 11.1 0.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) RNA_pol_A_bac PF01000.26 EGG00521.1 - 1.3e-21 77.1 0.0 3.1e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGG00521.1 - 1.8e-18 65.7 0.0 2.5e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DAO PF01266.24 EGG00523.1 - 4.3e-42 145.0 0.0 5.2e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG00523.1 - 0.0024 17.1 0.0 0.043 13.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG00523.1 - 0.15 12.4 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ABG_transport PF03806.13 EGG00525.1 - 0.038 12.2 0.1 0.04 12.2 0.1 1.0 1 0 0 1 1 1 0 AbgT putative transporter family PCP PF02429.15 EGG00525.1 - 0.087 13.1 0.0 0.096 13.0 0.0 1.0 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein 3HCDH PF00725.22 EGG00526.1 - 2.4e-19 69.7 0.0 5.1e-19 68.7 0.0 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.18 EGG00526.1 - 5.8e-06 26.3 0.0 9.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 EGG00527.1 - 3.2e-21 75.9 0.1 1.4e-17 63.9 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG00527.1 - 5.7e-11 42.2 0.0 6.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase GatB_N PF02934.15 EGG00528.1 - 2.6e-102 341.9 0.0 3.4e-102 341.5 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EGG00528.1 - 1e-16 61.2 0.1 3.4e-14 52.9 0.1 2.3 1 1 0 1 1 1 1 GatB domain Streptin-Immun PF11083.8 EGG00528.1 - 0.084 13.3 0.1 0.2 12.1 0.1 1.6 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein DUF5109 PF17134.4 EGG00528.1 - 0.18 11.7 0.0 0.46 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5109) Ribonuclease_3 PF00636.26 EGG00529.1 - 8e-06 26.4 0.0 1.5e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain TM2 PF05154.16 EGG00529.1 - 0.00081 19.7 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 TM2 domain DUF684 PF05075.14 EGG00529.1 - 0.037 13.0 0.1 0.049 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF684) MerC PF03203.14 EGG00530.1 - 0.019 15.4 7.6 0.047 14.2 1.6 2.5 2 1 0 2 2 2 0 MerC mercury resistance protein Spo7 PF03907.13 EGG00530.1 - 0.36 10.3 10.2 2.1 7.7 0.0 3.2 2 1 1 3 3 3 0 Spo7-like protein DUF202 PF02656.15 EGG00530.1 - 0.6 10.6 10.0 1 9.9 0.4 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) CDC73_C PF05179.14 EGG00531.1 - 0.0015 18.2 0.1 0.0051 16.5 0.1 1.7 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal FH2 PF02181.23 EGG00531.1 - 0.041 13.0 0.1 0.062 12.4 0.1 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain Abhydrolase_1 PF00561.20 EGG00532.1 - 9.2e-25 87.7 0.0 5.6e-24 85.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG00532.1 - 1.9e-19 71.2 1.0 7.9e-19 69.1 1.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG00532.1 - 2.1e-08 33.8 0.0 4.5e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 EGG00532.1 - 0.0076 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 EGG00532.1 - 0.059 13.1 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family NOG1_N PF17835.1 EGG00533.1 - 1.5e-49 168.1 0.2 3.9e-49 166.7 0.2 1.8 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 EGG00533.1 - 1e-26 92.4 0.1 2.3e-26 91.3 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 EGG00533.1 - 7e-22 77.2 0.7 6.1e-16 58.2 0.6 2.9 2 0 0 2 2 2 2 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 EGG00533.1 - 3.6e-17 62.5 0.0 1.1e-16 61.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG00533.1 - 1.2e-08 34.7 0.0 3.4e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGG00533.1 - 0.013 15.6 2.3 1.7 8.7 0.0 3.4 3 1 1 4 4 4 0 Dynamin family AIG1 PF04548.16 EGG00533.1 - 0.031 13.6 0.0 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 AIG1 family RsgA_GTPase PF03193.16 EGG00533.1 - 0.037 13.9 0.1 3.6 7.4 0.0 3.4 3 1 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 EGG00533.1 - 0.04 14.3 0.0 0.88 9.9 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain LsmAD PF06741.13 EGG00533.1 - 0.091 13.3 3.3 0.32 11.6 3.3 1.9 1 0 0 1 1 1 0 LsmAD domain Sushi_2 PF09014.10 EGG00533.1 - 0.13 12.1 0.1 0.42 10.5 0.1 1.8 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain RR_TM4-6 PF06459.12 EGG00535.1 - 0.015 15.1 5.8 0.023 14.5 5.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EOS1 PF12326.8 EGG00535.1 - 2.1 8.2 6.7 5.3 6.9 6.7 1.6 1 1 0 1 1 1 0 N-glycosylation protein Vfa1 PF08432.10 EGG00535.1 - 2.5 8.4 14.6 4.3 7.6 14.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 V_ATPase_I PF01496.19 EGG00535.1 - 4.6 5.0 7.4 5.9 4.7 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PGAP1 PF07819.13 EGG00538.1 - 4.9e-06 26.4 0.1 6.5e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 EGG00538.1 - 0.00018 21.4 0.1 0.00024 21.0 0.1 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EGG00538.1 - 0.00089 18.8 0.1 0.0013 18.2 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2974 PF11187.8 EGG00538.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pex19 PF04614.12 EGG00541.1 - 0.031 14.1 0.8 0.031 14.1 0.8 1.6 2 0 0 2 2 2 0 Pex19 protein family DUF4458 PF14660.6 EGG00541.1 - 0.075 13.3 0.3 1.3 9.3 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4458) DUF2680 PF10925.8 EGG00541.1 - 0.11 12.5 0.3 0.11 12.5 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2680) YkyA PF10368.9 EGG00541.1 - 0.26 11.0 10.6 0.19 11.4 2.9 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein ZapB PF06005.12 EGG00541.1 - 0.56 10.7 12.6 0.91 10.0 2.2 2.5 2 0 0 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 EGG00541.1 - 1.3 9.5 11.4 4.8 7.7 0.7 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region MerR-DNA-bind PF09278.11 EGG00541.1 - 1.7 9.3 9.9 1.7 9.2 0.1 3.5 3 1 1 4 4 4 0 MerR, DNA binding YabA PF06156.13 EGG00541.1 - 2.9 8.6 7.0 8.5 7.1 1.6 2.3 2 0 0 2 2 2 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 EGG00541.1 - 5.1 7.3 11.8 13 6.0 3.3 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc24 PF08286.11 EGG00541.1 - 7 6.9 8.2 1.8 8.8 0.5 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DWNN PF08783.11 EGG00543.1 - 0.071 13.4 1.1 2.8 8.3 0.0 2.8 3 0 0 3 3 3 0 DWNN domain ExbD PF02472.16 EGG00543.1 - 0.53 10.5 7.3 0.63 10.2 1.8 2.6 2 1 1 3 3 3 0 Biopolymer transport protein ExbD/TolR JmjC PF02373.22 EGG00544.1 - 2.3e-13 50.5 0.0 4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGG00544.1 - 0.0028 17.4 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Ribosomal_L26 PF16906.5 EGG00544.1 - 0.0089 16.5 0.1 0.017 15.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal proteins L26 eukaryotic, L24P archaeal Cupin_2 PF07883.11 EGG00544.1 - 0.053 13.2 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Cupin domain MFS_1 PF07690.16 EGG00547.1 - 5.8e-27 94.5 30.2 7.3e-27 94.2 30.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HKR_ArcB_TM PF18415.1 EGG00547.1 - 0.062 14.1 0.4 19 6.1 0.5 3.3 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain Glucan_synthase PF02364.15 EGG00547.1 - 0.11 10.6 0.3 0.21 9.7 0.3 1.3 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Sprouty PF05210.13 EGG00547.1 - 0.2 12.0 0.4 0.6 10.5 0.4 1.8 1 0 0 1 1 1 0 Sprouty protein (Spry) MFS_1 PF07690.16 EGG00548.1 - 2.7e-21 75.9 26.8 1.2e-18 67.1 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glucan_synthase PF02364.15 EGG00548.1 - 0.038 12.2 0.9 0.066 11.4 0.9 1.3 1 0 0 1 1 1 0 1,3-beta-glucan synthase component SQS_PSY PF00494.19 EGG00549.1 - 3.4e-37 128.4 0.0 4.1e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Syndecan PF01034.20 EGG00550.1 - 0.064 13.2 1.3 0.07 13.1 1.3 1.1 1 0 0 1 1 1 0 Syndecan domain LAX PF15681.5 EGG00550.1 - 0.31 9.8 0.3 0.35 9.6 0.3 1.0 1 0 0 1 1 1 0 Lymphocyte activation family X CxC1 PF18802.1 EGG00551.1 - 0.00063 19.9 0.1 0.0011 19.1 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGG00551.1 - 0.039 13.6 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase DUF4419 PF14388.6 EGG00552.1 - 0.0078 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) PUMA PF15826.5 EGG00553.1 - 0.026 14.7 0.7 0.057 13.6 0.7 1.5 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis amfpi-1 PF12190.8 EGG00559.1 - 0.064 13.9 0.2 0.15 12.7 0.2 1.6 1 0 0 1 1 1 0 Fungal protease inhibitor Collagen PF01391.18 EGG00560.1 - 2.5e-05 23.9 14.3 9.2e-05 22.1 14.3 1.9 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF445 PF04286.12 EGG00562.1 - 0.035 13.9 2.8 0.04 13.7 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Ecl1 PF12855.7 EGG00562.1 - 0.96 10.6 4.2 2.3 9.3 4.2 1.7 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF2236 PF09995.9 EGG00563.1 - 1.6e-08 35.1 0.0 2.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) zf-CCCH PF00642.24 EGG00564.1 - 1.2e-17 63.3 20.4 6.2e-11 41.9 2.6 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGG00564.1 - 1.6e-06 28.0 2.8 1.6e-06 28.0 2.8 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EGG00564.1 - 9.7e-06 25.3 18.9 0.0061 16.3 0.6 2.5 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EGG00564.1 - 0.094 13.2 0.2 0.094 13.2 0.2 2.9 3 1 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Defensin_int PF17858.1 EGG00564.1 - 0.47 10.5 6.5 0.19 11.7 3.5 1.8 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide Torus PF16131.5 EGG00564.1 - 0.75 10.5 13.6 3.3 8.4 6.0 2.0 1 1 1 2 2 2 0 Torus domain AWS PF17907.1 EGG00564.1 - 5.3 7.2 10.1 12 6.0 4.9 2.4 2 0 0 2 2 2 0 AWS domain AMP-binding PF00501.28 EGG00565.1 - 3.6e-25 88.5 0.0 1.5e-24 86.4 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EGG00565.1 - 0.0002 21.6 0.0 0.00041 20.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Mnd1 PF03962.15 EGG00567.1 - 0.09 13.1 0.3 0.24 11.7 0.3 1.8 1 0 0 1 1 1 0 Mnd1 HTH domain Sdh5 PF03937.16 EGG00567.1 - 0.11 12.5 1.1 2.1 8.4 0.0 3.1 4 0 0 4 4 4 0 Flavinator of succinate dehydrogenase LRR_4 PF12799.7 EGG00568.1 - 2.7e-13 49.9 14.9 0.076 13.5 0.0 7.6 3 2 2 8 8 8 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGG00568.1 - 1e-10 41.3 1.4 1e-10 41.3 1.4 2.3 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 EGG00568.1 - 5.6e-07 29.1 37.4 0.082 13.0 0.2 10.3 11 0 0 11 11 11 5 Leucine Rich repeat F-box PF00646.33 EGG00568.1 - 0.034 14.0 5.0 0.047 13.6 0.8 3.0 2 0 0 2 2 2 0 F-box domain F-box_5 PF18511.1 EGG00568.1 - 0.11 12.1 0.2 0.28 10.8 0.2 1.7 1 0 0 1 1 1 0 F-box LRR_1 PF00560.33 EGG00568.1 - 0.24 12.1 15.2 99 4.1 0.3 8.1 6 2 1 7 7 7 0 Leucine Rich Repeat ORC6 PF05460.13 EGG00569.1 - 0.59 9.3 4.0 0.71 9.1 4.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-C2H2_12 PF18658.1 EGG00570.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger C2H2-type PPR_2 PF13041.6 EGG00573.1 - 8.1e-12 45.1 0.1 9.1e-05 22.6 0.0 5.1 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.20 EGG00573.1 - 6.2e-05 23.0 0.2 14 6.2 0.0 4.5 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 EGG00573.1 - 0.00065 19.7 0.0 21 5.3 0.0 5.1 4 1 1 5 5 5 1 Pentatricopeptide repeat domain GAIN PF16489.5 EGG00573.1 - 0.052 13.0 0.4 0.052 13.0 0.4 1.9 2 0 0 2 2 2 0 GPCR-Autoproteolysis INducing (GAIN) domain Mx_ML PF17536.2 EGG00573.1 - 0.057 13.1 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Matrix and Matrix long proteins N-terminal NCA2 PF08637.10 EGG00574.1 - 6.4e-55 186.4 1.7 7.5e-28 97.5 0.7 2.3 2 0 0 2 2 2 2 ATP synthase regulation protein NCA2 ERGIC_N PF13850.6 EGG00574.1 - 0.0019 18.5 1.0 0.034 14.5 0.0 3.0 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) GPW_gp25 PF04965.14 EGG00574.1 - 0.096 12.5 0.2 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Gene 25-like lysozyme Zeta_toxin PF06414.12 EGG00575.1 - 0.049 12.9 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin DUF4661 PF15576.6 EGG00577.1 - 1.2 9.0 7.4 3.2 7.6 7.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Glyco_hydro_92N PF17678.1 EGG00578.1 - 0.033 14.1 0.1 0.039 13.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 N-terminal domain Phage_int_SAM_1 PF02899.17 EGG00578.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Bse634I PF07832.11 EGG00578.1 - 0.17 11.2 0.5 0.41 10.0 0.0 1.7 2 0 0 2 2 2 0 Cfr10I/Bse634I restriction endonuclease Phage_int_SAM_5 PF13102.6 EGG00578.1 - 0.18 12.2 1.5 0.57 10.6 0.3 2.0 2 0 0 2 2 2 0 Phage integrase SAM-like domain CxC5 PF18718.1 EGG00581.1 - 6e-32 110.2 5.0 9.2e-32 109.6 5.0 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases DUF4604 PF15377.6 EGG00582.1 - 3e-17 63.6 16.2 1.8e-10 41.6 11.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4604) Herpes_LMP1 PF05297.11 EGG00582.1 - 1.4 8.0 3.1 2 7.6 3.1 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) TFIIE-A_C PF11521.8 EGG00582.1 - 3.6 7.9 8.7 0.38 11.1 3.3 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Sua5_yciO_yrdC PF01300.18 EGG00583.1 - 4e-52 176.3 0.0 6e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EGG00583.1 - 8.9e-23 81.3 0.0 1.9e-22 80.3 0.0 1.6 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Tetrabrachion PF11401.8 EGG00585.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Tetrabrachion Ribosomal_L1 PF00687.21 EGG00586.1 - 3.7e-48 164.0 2.3 4.2e-48 163.8 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family EVI2A PF05399.11 EGG00587.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) LRR_8 PF13855.6 EGG00588.1 - 3e-06 26.9 1.6 0.091 12.5 0.0 3.8 4 0 0 4 4 4 2 Leucine rich repeat LRR_5 PF13306.6 EGG00588.1 - 3e-05 24.0 1.8 0.059 13.3 0.2 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) GST_C_6 PF17171.4 EGG00588.1 - 0.23 11.3 2.2 14 5.6 0.1 3.0 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain LRR_4 PF12799.7 EGG00588.1 - 2.1 8.9 6.6 22 5.7 0.1 4.3 3 2 0 4 4 4 0 Leucine Rich repeats (2 copies) WD40 PF00400.32 EGG00589.1 - 8e-07 29.7 1.1 0.21 12.5 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Glyco_hydro_101 PF12905.7 EGG00590.1 - 0.034 13.5 0.1 0.045 13.2 0.1 1.2 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase AAA_12 PF13087.6 EGG00591.1 - 1.6e-53 181.3 0.2 9e-53 178.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EGG00591.1 - 1.1e-48 166.3 0.3 1.1e-48 166.3 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGG00591.1 - 6.2e-13 48.9 0.0 1.8e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGG00591.1 - 2.2e-11 44.3 0.0 1.3e-10 41.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGG00591.1 - 1.6e-05 24.8 0.7 0.43 10.3 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EGG00591.1 - 0.01 15.7 0.1 0.88 9.4 0.1 2.6 1 1 0 1 1 1 0 Helicase UvrD_C_2 PF13538.6 EGG00591.1 - 0.056 13.3 0.0 0.22 11.4 0.0 2.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 EGG00591.1 - 0.16 12.4 0.2 0.51 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) VbhA PF18495.1 EGG00592.1 - 5e-08 32.7 7.0 1.7e+02 2.2 0.0 12.9 15 0 0 15 15 15 0 Antitoxin VbhA NOA36 PF06524.12 EGG00592.1 - 5.5 6.2 7.3 8.8 5.5 7.3 1.2 1 0 0 1 1 1 0 NOA36 protein Rad21_Rec8_N PF04825.13 EGG00593.1 - 1.1e-26 93.1 0.0 2.1e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGG00593.1 - 4.1e-07 29.2 0.0 9.5e-07 28.0 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Radial_spoke_3 PF06098.11 EGG00593.1 - 0.24 10.7 4.2 0.5 9.6 4.2 1.5 1 0 0 1 1 1 0 Radial spoke protein 3 TetR_C_28 PF17937.1 EGG00594.1 - 0.27 11.7 0.6 0.43 11.1 0.6 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CAP_N PF01213.19 EGG00594.1 - 6.8 6.1 15.7 6.5 6.1 7.2 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Red1 PF07964.11 EGG00595.1 - 0.18 10.0 1.8 0.23 9.7 1.8 1.0 1 0 0 1 1 1 0 Rec10 / Red1 PRELI PF04707.14 EGG00596.1 - 1.6e-30 106.0 0.0 2.2e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family NPV_P10 PF05531.12 EGG00602.1 - 0.22 12.0 2.1 0.48 10.9 1.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMEM215 PF15746.5 EGG00606.1 - 1.1 8.7 3.9 2.1 7.7 3.9 1.4 1 0 0 1 1 1 0 TMEM215 family DUF4407 PF14362.6 EGG00606.1 - 1.7 8.0 8.5 2.2 7.5 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UBX PF00789.20 EGG00607.1 - 3e-05 24.1 0.0 0.00011 22.4 0.0 1.9 1 1 0 1 1 1 1 UBX domain UBA PF00627.31 EGG00607.1 - 0.00022 21.1 0.0 0.0012 18.7 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain zf-C2H2 PF00096.26 EGG00607.1 - 0.14 12.7 0.2 0.3 11.6 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2604 PF10790.9 EGG00607.1 - 0.29 11.4 1.2 2.5 8.5 0.3 2.5 2 0 0 2 2 2 0 Protein of Unknown function (DUF2604) PhoLip_ATPase_C PF16212.5 EGG00609.1 - 1.7e-49 168.9 23.3 1.7e-49 168.9 23.3 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGG00609.1 - 3.1e-16 58.8 5.0 7.8e-16 57.5 5.0 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGG00609.1 - 1.6e-14 54.7 0.5 4.2e-09 37.0 0.6 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGG00609.1 - 2e-10 40.5 11.1 1.7e-05 24.4 0.0 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 EGG00609.1 - 2.8e-10 40.1 0.0 2.5e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGG00609.1 - 0.0025 17.6 0.0 0.0061 16.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Spore_YhaL PF14147.6 EGG00609.1 - 3.3 7.5 6.8 0.25 11.0 1.6 1.8 2 0 0 2 2 2 0 Sporulation protein YhaL DUF1772 PF08592.11 EGG00609.1 - 6.4 7.1 9.1 1.2 9.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) HCNGP PF07818.13 EGG00613.1 - 3.4e-29 101.3 0.2 6.5e-29 100.4 0.2 1.4 1 0 0 1 1 1 1 HCNGP-like protein PRP38_assoc PF12871.7 EGG00613.1 - 0.0054 17.3 26.1 0.016 15.8 26.1 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term NIF3 PF01784.18 EGG00615.1 - 2.3e-63 214.1 0.0 2.7e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Defensin_5 PF18251.1 EGG00615.1 - 1 9.5 4.3 0.35 11.0 1.2 1.8 2 0 0 2 2 2 0 Fungal defensin Copsin Glyco_hydro_7 PF00840.20 EGG00616.1 - 1.4e-201 669.9 12.9 1.5e-201 669.8 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CLZ PF16526.5 EGG00618.1 - 0.0034 17.7 6.3 0.068 13.5 1.1 2.5 1 1 1 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels UPF0242 PF06785.11 EGG00618.1 - 0.0091 16.1 5.7 0.016 15.3 5.7 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 EGG00618.1 - 0.029 13.7 1.3 0.059 12.7 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YscO PF07321.12 EGG00618.1 - 0.03 14.3 1.7 0.092 12.7 0.1 2.2 1 1 1 2 2 2 0 Type III secretion protein YscO DUF812 PF05667.11 EGG00618.1 - 0.035 13.0 13.4 0.13 11.1 13.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) BLOC1_2 PF10046.9 EGG00618.1 - 0.052 13.8 4.6 0.37 11.1 1.3 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 EGG00618.1 - 0.092 13.2 3.3 11 6.5 0.3 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 EGG00618.1 - 0.099 13.0 3.9 9 6.7 0.1 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Lzipper-MIP1 PF14389.6 EGG00618.1 - 0.14 12.5 3.7 2.2 8.7 0.3 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 HSBP1 PF06825.12 EGG00618.1 - 0.29 11.0 4.4 8.7 6.3 0.5 2.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 FapA PF03961.13 EGG00618.1 - 0.46 9.0 4.2 0.63 8.6 4.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ABC_tran_CTD PF16326.5 EGG00618.1 - 0.47 10.7 5.5 14 6.0 2.6 2.7 1 1 1 2 2 2 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 EGG00618.1 - 0.74 10.0 10.5 1.7 8.8 3.5 2.7 1 1 1 3 3 3 0 Tropomyosin like YlbD_coat PF14071.6 EGG00618.1 - 2.7 8.3 10.0 0.35 11.1 5.2 2.0 2 1 0 2 2 2 0 Putative coat protein SlyX PF04102.12 EGG00618.1 - 4.1 8.1 12.6 0.9 10.2 2.2 3.3 3 1 1 4 4 2 0 SlyX Pox_A_type_inc PF04508.12 EGG00618.1 - 4.4 7.3 5.7 3.1 7.8 0.2 3.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat ABC_tran PF00005.27 EGG00619.1 - 1.4e-15 58.0 0.1 5.1e-15 56.2 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGG00619.1 - 1.8e-09 37.9 1.8 0.00021 21.2 0.2 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGG00619.1 - 0.00058 19.6 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGG00619.1 - 0.0081 15.6 0.2 2.5 7.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGG00619.1 - 0.0087 16.1 0.0 0.024 14.7 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 EGG00619.1 - 0.017 14.7 0.0 0.048 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGG00619.1 - 0.017 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EGG00619.1 - 0.025 14.5 1.5 0.13 12.2 0.1 2.3 2 1 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 EGG00619.1 - 0.029 14.1 0.1 0.041 13.6 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 EGG00619.1 - 0.03 14.6 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EGG00619.1 - 0.034 14.1 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 EGG00619.1 - 0.045 14.0 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGG00619.1 - 0.047 13.9 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG00619.1 - 0.049 14.0 0.3 0.079 13.3 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EGG00619.1 - 0.049 14.1 0.1 0.075 13.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EGG00619.1 - 0.057 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.6 EGG00619.1 - 0.11 12.7 0.4 0.37 11.0 0.4 1.9 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 EGG00619.1 - 0.26 10.4 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_13 PF13166.6 EGG00619.1 - 0.34 9.5 0.0 0.52 8.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2423 PF10338.9 EGG00621.1 - 9.2e-17 61.0 9.8 1.4e-16 60.4 9.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Laps PF10169.9 EGG00621.1 - 0.44 11.1 13.0 1 9.9 13.0 1.7 1 1 0 1 1 1 0 Learning-associated protein GalKase_gal_bdg PF10509.9 EGG00622.1 - 1.1e-19 69.7 0.1 2.1e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EGG00622.1 - 1.8e-12 47.3 0.1 4.9e-12 45.9 0.1 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGG00622.1 - 9.3e-12 45.2 0.0 2.3e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal RRN9 PF10680.9 EGG00624.1 - 0.06 13.6 0.2 0.06 13.6 0.2 2.6 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor Zn_ribbon_SprT PF17283.2 EGG00624.1 - 0.19 11.7 6.4 0.076 12.9 3.0 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2 PF00096.26 EGG00624.1 - 4.7 7.9 5.6 14 6.4 0.5 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Alpha_kinase PF02816.18 EGG00625.1 - 3e-34 118.7 0.4 3.6e-34 118.5 0.4 1.1 1 0 0 1 1 1 1 Alpha-kinase family Mucin PF01456.17 EGG00626.1 - 0.0054 16.7 4.6 0.0085 16.1 4.6 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3439 PF11921.8 EGG00626.1 - 0.9 9.5 6.3 1.6 8.7 6.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Melibiase_2 PF16499.5 EGG00627.1 - 4.7e-61 206.5 8.6 1.4e-60 204.9 8.6 1.8 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 EGG00627.1 - 5.5e-05 22.3 0.0 0.00019 20.5 0.0 1.7 2 0 0 2 2 2 1 Melibiase Melibiase_C PF17801.1 EGG00627.1 - 0.0062 16.6 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain DUF5619 PF18505.1 EGG00629.1 - 0.013 15.5 0.3 0.37 10.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5619) Glyco_hydro_3 PF00933.21 EGG00630.1 - 4.9e-52 177.3 0.0 7.5e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EGG00630.1 - 3.4e-48 164.3 0.0 5.6e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EGG00630.1 - 3.7e-20 71.8 0.0 1.3e-19 70.1 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Pico_P2B PF01552.17 EGG00630.1 - 0.0081 16.3 0.4 0.082 13.1 0.0 2.6 3 0 0 3 3 3 1 Picornavirus 2B protein UPF0147 PF03685.13 EGG00631.1 - 0.075 13.1 0.1 0.5 10.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) Med2 PF11214.8 EGG00631.1 - 0.19 11.9 1.8 0.31 11.2 0.3 2.1 2 0 0 2 2 2 0 Mediator complex subunit 2 DUF5364 PF17322.2 EGG00631.1 - 0.24 11.7 1.6 1.9 8.8 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5364) Bac_rhodopsin PF01036.18 EGG00632.1 - 1.3e-46 159.0 17.0 1.9e-46 158.5 17.0 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2754 PF10953.8 EGG00632.1 - 8.7 6.7 9.4 5.5 7.3 4.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2754) Rhodanese PF00581.20 EGG00633.1 - 1.6e-12 47.9 0.0 1.8e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain PCI PF01399.27 EGG00634.1 - 6.4e-08 33.1 1.5 2.6e-07 31.1 0.1 2.6 2 0 0 2 2 2 1 PCI domain MinE PF03776.14 EGG00636.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.8 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE CTP-dep_RFKase PF01982.16 EGG00638.1 - 0.025 14.7 0.1 0.054 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF120 PGA2 PF07543.12 EGG00638.1 - 0.094 12.7 0.7 0.18 11.8 0.7 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Abhydrolase_1 PF00561.20 EGG00639.1 - 7.3e-10 38.9 0.4 1.6e-09 37.8 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG00639.1 - 3.3e-05 24.6 0.0 5e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Dak1 PF02733.17 EGG00640.1 - 1.5e-111 372.3 2.5 2e-111 371.9 2.5 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EGG00640.1 - 1.5e-37 129.2 0.8 1.5e-37 129.2 0.8 2.3 3 0 0 3 3 3 1 DAK2 domain Resistin PF06954.11 EGG00641.1 - 0.14 12.7 10.6 15 6.2 0.1 4.3 4 1 0 4 4 4 0 Resistin Ppx-GppA PF02541.16 EGG00642.1 - 0.11 12.0 0.3 0.21 11.0 0.3 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Phage_DNA_bind PF02303.17 EGG00643.1 - 0.036 14.3 0.1 0.069 13.4 0.1 1.4 1 0 0 1 1 1 0 Helix-destabilising protein CW_binding_1 PF01473.20 EGG00643.1 - 0.83 10.1 2.6 1.9 8.9 2.6 1.7 1 0 0 1 1 1 0 Putative cell wall binding repeat V-SNARE_C PF12352.8 EGG00646.1 - 1.2e-15 57.5 0.8 3.2e-15 56.2 0.8 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EGG00646.1 - 0.00098 19.0 2.1 0.0054 16.6 0.0 2.8 2 2 1 3 3 3 1 Sec20 GCR PF02155.15 EGG00646.1 - 0.0051 15.9 0.3 0.0093 15.0 0.3 1.4 1 0 0 1 1 1 1 Glucocorticoid receptor Death PF00531.22 EGG00646.1 - 0.1 12.8 0.0 0.56 10.4 0.0 2.1 1 1 1 2 2 2 0 Death domain Transp_cyt_pur PF02133.15 EGG00647.1 - 4.1e-40 137.9 30.0 5.6e-40 137.4 30.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_hydro_18 PF00704.28 EGG00648.1 - 3.5e-57 194.5 0.0 4e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_114 PF03537.13 EGG00648.1 - 0.059 12.7 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 Peptidase_S10 PF00450.22 EGG00649.1 - 2.1e-68 231.7 0.9 4.4e-67 227.3 0.9 2.4 1 1 0 1 1 1 1 Serine carboxypeptidase COesterase PF00135.28 EGG00650.1 - 2.8e-73 247.6 0.0 3.5e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EGG00650.1 - 0.0026 17.3 0.1 0.0038 16.7 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGG00650.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SesA PF17107.5 EGG00651.1 - 0.012 15.8 0.3 0.019 15.1 0.3 1.3 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HBM PF16591.5 EGG00651.1 - 0.026 13.9 0.7 0.039 13.4 0.7 1.2 1 0 0 1 1 1 0 Helical bimodular sensor domain Glyco_hydr_116N PF12215.8 EGG00653.1 - 0.003 17.1 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Myb_DNA-binding PF00249.31 EGG00654.1 - 0.012 15.8 0.1 0.031 14.5 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG00654.1 - 0.089 13.1 0.3 0.089 13.1 0.3 2.3 3 1 0 3 3 3 0 Myb-like DNA-binding domain zf-CCCH PF00642.24 EGG00655.1 - 3.4e-11 42.8 18.4 3.4e-06 26.8 2.1 4.4 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGG00655.1 - 0.00081 19.4 24.4 0.0074 16.3 2.1 4.2 5 0 0 5 5 5 2 Zinc finger domain zf-CCCH_3 PF15663.5 EGG00655.1 - 0.069 13.4 18.4 0.39 10.9 7.6 3.5 2 1 2 4 4 4 0 Zinc-finger containing family Torus PF16131.5 EGG00655.1 - 0.87 10.3 16.6 0.27 12.0 2.0 3.3 1 1 2 3 3 3 0 Torus domain DnaJ PF00226.31 EGG00656.1 - 2.8e-20 72.2 0.3 6.2e-20 71.1 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Gon7 PF08738.10 EGG00657.1 - 0.021 14.9 0.4 0.031 14.4 0.3 1.4 1 1 0 1 1 1 0 Gon7 family CppA_N PF14506.6 EGG00659.1 - 0.021 14.9 0.6 0.04 14.0 0.1 1.7 2 0 0 2 2 2 0 CppA N-terminal TPR_MLP1_2 PF07926.12 EGG00659.1 - 0.15 12.2 7.7 0.29 11.2 7.7 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 EGG00659.1 - 0.15 12.7 7.4 0.08 13.6 3.0 2.5 2 0 0 2 2 2 0 SlyX Snapin_Pallidin PF14712.6 EGG00659.1 - 0.17 12.4 3.7 0.5 10.8 1.3 2.8 2 1 0 2 2 2 0 Snapin/Pallidin DivIC PF04977.15 EGG00659.1 - 0.33 10.7 4.1 0.27 11.0 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator TRAF_BIRC3_bd PF16673.5 EGG00659.1 - 0.84 9.5 3.2 4.1 7.3 0.9 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Prefoldin PF02996.17 EGG00659.1 - 1.6 8.7 6.5 15 5.5 0.5 2.9 1 1 2 3 3 3 0 Prefoldin subunit NPV_P10 PF05531.12 EGG00659.1 - 2.9 8.4 7.5 3.3 8.3 4.2 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Acyl_transf_1 PF00698.21 EGG00661.1 - 2.5e-60 204.7 0.0 3e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain DUF5093 PF17011.5 EGG00661.1 - 0.064 13.6 0.3 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) ketoacyl-synt PF00109.26 EGG00662.1 - 1.8e-27 96.5 0.2 3.1e-27 95.7 0.2 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAS_I_H PF18314.1 EGG00662.1 - 5.6e-27 94.7 0.0 9.6e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Ketoacyl-synt_C PF02801.22 EGG00662.1 - 3.6e-16 59.2 0.1 2.6e-14 53.2 0.0 2.8 1 1 1 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 EGG00662.1 - 1.4e-12 47.7 0.1 3.1e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 EGG00662.1 - 0.0021 17.5 0.0 0.0054 16.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG00662.1 - 0.0059 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 KR domain Condensation PF00668.20 EGG00663.1 - 0.007 15.1 0.1 0.011 14.5 0.1 1.2 1 0 0 1 1 1 1 Condensation domain Synaptobrevin PF00957.21 EGG00663.1 - 0.015 15.1 1.1 0.038 13.8 1.1 1.6 1 0 0 1 1 1 0 Synaptobrevin Baculo_PEP_C PF04513.12 EGG00663.1 - 0.31 11.1 5.6 0.47 10.5 4.2 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol PF00940.19 EGG00664.1 - 4.2e-168 559.5 0.0 5.5e-168 559.1 0.0 1.1 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EGG00664.1 - 2.9e-57 194.6 0.0 4.3e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Thg1 PF04446.12 EGG00665.1 - 1.6e-45 154.2 0.0 2.6e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EGG00665.1 - 4.4e-40 136.6 0.1 6.6e-40 136.1 0.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain F-box-like PF12937.7 EGG00666.1 - 0.019 14.8 1.2 0.42 10.5 0.0 3.3 3 2 0 3 3 3 0 F-box-like Ribosomal_L13 PF00572.18 EGG00667.1 - 0.09 13.0 0.2 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L13 Alpha_kinase PF02816.18 EGG00668.1 - 4.3e-16 59.6 0.0 6.4e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family STAT_alpha PF01017.20 EGG00669.1 - 0.023 14.6 0.7 1.6 8.6 0.2 2.7 2 1 1 3 3 3 0 STAT protein, all-alpha domain Arm-DNA-bind_2 PF12167.8 EGG00669.1 - 0.18 11.7 0.5 16 5.5 0.1 2.5 2 0 0 2 2 2 0 Arm DNA-binding domain CCDC106 PF15794.5 EGG00672.1 - 0.078 12.7 7.3 0.16 11.6 7.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 EGG00672.1 - 0.59 8.3 4.3 1.1 7.4 4.3 1.4 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.10 EGG00673.1 - 0.027 13.9 13.3 0.032 13.6 13.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mit_KHE1 PF10173.9 EGG00673.1 - 0.24 11.5 2.1 0.3 11.2 2.1 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related MG3 PF17791.1 EGG00675.1 - 0.1 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Macroglobulin domain MG3 Coilin_N PF15862.5 EGG00678.1 - 0.045 13.5 9.0 0.053 13.3 9.0 1.2 1 0 0 1 1 1 0 Coilin N-terminus DUF463 PF04317.12 EGG00678.1 - 0.12 11.2 2.8 0.14 11.1 2.8 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 TUTF7_u4 PF16631.5 EGG00678.1 - 0.62 10.7 9.1 0.91 10.2 9.1 1.3 1 0 0 1 1 1 0 Unstructured region 4 on terminal uridylyltransferase 7 SRP-alpha_N PF04086.13 EGG00678.1 - 1.2 9.0 11.7 1.4 8.8 11.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MCM_bind PF09739.9 EGG00678.1 - 4.4 5.6 10.0 4.6 5.6 10.0 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Hydin_ADK PF17213.3 EGG00678.1 - 7.7 6.7 10.5 9.4 6.5 10.5 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Paralemmin PF03285.15 EGG00679.1 - 0.0089 15.6 8.7 0.17 11.5 6.4 2.4 2 0 0 2 2 2 1 Paralemmin DUF4407 PF14362.6 EGG00679.1 - 0.032 13.6 3.8 0.046 13.1 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PmbA_TldD PF01523.16 EGG00679.1 - 0.037 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Tropomyosin_1 PF12718.7 EGG00679.1 - 0.038 14.1 15.5 0.068 13.3 13.3 2.1 1 1 1 2 2 2 0 Tropomyosin like Csm1_N PF18504.1 EGG00679.1 - 0.12 12.7 5.5 1.3 9.4 0.9 2.8 2 0 0 2 2 2 0 Csm1 N-terminal domain CENP-F_leu_zip PF10473.9 EGG00679.1 - 0.17 11.9 11.2 0.3 11.1 10.3 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC53 PF10152.9 EGG00679.1 - 0.22 11.9 4.0 0.71 10.3 4.0 1.8 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Noelin-1 PF12308.8 EGG00679.1 - 0.48 10.4 3.0 1.1 9.3 3.0 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein CLZ PF16526.5 EGG00679.1 - 0.62 10.5 9.6 0.39 11.1 3.0 2.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 EGG00679.1 - 0.85 9.8 7.2 12 6.1 2.6 2.8 1 1 0 2 2 2 0 bZIP transcription factor SlyX PF04102.12 EGG00679.1 - 1.7 9.3 7.6 41 4.9 7.3 2.6 1 1 1 2 2 2 0 SlyX XhlA PF10779.9 EGG00679.1 - 2.3 8.5 7.5 6.6 7.0 1.7 2.8 1 1 1 2 2 2 0 Haemolysin XhlA FlaC_arch PF05377.11 EGG00679.1 - 2.6 8.5 4.8 7.8 7.0 0.2 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 EGG00679.1 - 3.1 8.1 10.0 9.7 6.5 9.2 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4094 PF13334.6 EGG00679.1 - 3.2 8.2 6.8 2.4 8.6 0.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) CCDC106 PF15794.5 EGG00679.1 - 3.5 7.3 15.2 0.052 13.2 3.1 2.9 2 1 0 3 3 3 0 Coiled-coil domain-containing protein 106 bZIP_2 PF07716.15 EGG00679.1 - 5.2 7.2 9.5 8.7 6.5 3.5 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Jnk-SapK_ap_N PF09744.9 EGG00679.1 - 6.9 6.9 14.7 0.57 10.4 9.9 1.7 2 0 0 2 2 1 0 JNK_SAPK-associated protein-1 SLIDE PF09111.10 EGG00680.1 - 0.99 9.5 4.9 2.7 8.0 0.0 2.9 4 0 0 4 4 4 0 SLIDE DUF4200 PF13863.6 EGG00682.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) MIP-T3_C PF17749.1 EGG00683.1 - 0.027 14.4 0.8 0.22 11.5 0.2 2.1 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Pkinase PF00069.25 EGG00684.1 - 2.3e-64 217.3 0.0 2.7e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG00684.1 - 3.8e-33 114.9 0.0 5.2e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG00684.1 - 0.00029 20.2 0.0 0.00043 19.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG00684.1 - 0.0053 16.1 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG00684.1 - 0.056 13.4 0.1 2.2 8.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2232 PF09991.9 EGG00684.1 - 0.21 10.8 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Syntaxin_2 PF14523.6 EGG00685.1 - 0.19 12.1 0.9 0.48 10.8 0.2 2.0 3 0 0 3 3 3 0 Syntaxin-like protein Ribo_biogen_C PF04034.13 EGG00686.1 - 2.4e-48 163.0 0.0 3e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EGG00686.1 - 1.1e-14 53.9 0.0 1.9e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Cyclin PF08613.11 EGG00687.1 - 3.6e-08 33.9 0.0 7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGG00687.1 - 4.7e-08 32.8 0.1 8.2e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.32 EGG00688.1 - 6.6e-07 29.9 25.8 0.079 13.9 0.5 7.7 9 1 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG00688.1 - 3.5e-06 27.2 0.0 1 9.7 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TPT PF03151.16 EGG00689.1 - 3.6e-22 79.1 20.5 4.1e-22 78.9 20.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGG00689.1 - 1.1e-09 38.6 40.2 0.0001 22.5 16.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family FAM193_C PF15914.5 EGG00689.1 - 0.2 11.5 1.3 0.43 10.4 1.3 1.5 1 0 0 1 1 1 0 FAM193 family C-terminal Glyco_trans_1_2 PF13524.6 EGG00690.1 - 0.15 12.4 0.0 0.81 10.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 FKS1_dom1 PF14288.6 EGG00692.1 - 8.8e-20 71.4 1.6 8.3e-09 35.9 0.3 2.4 1 1 1 2 2 2 2 1,3-beta-glucan synthase subunit FKS1, domain-1 adh_short PF00106.25 EGG00693.1 - 1.3e-50 171.6 0.5 1.7e-50 171.2 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG00693.1 - 1.4e-34 119.7 0.1 1.8e-34 119.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG00693.1 - 3.5e-13 49.9 0.2 4.3e-13 49.6 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG00693.1 - 2e-05 24.2 0.1 2.7e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG00693.1 - 4.6e-05 23.0 0.1 6.6e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGG00693.1 - 0.00076 18.7 0.2 0.00094 18.4 0.2 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein PELOTA_1 PF15608.6 EGG00693.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 PELOTA RNA binding domain THF_DHG_CYH_C PF02882.19 EGG00693.1 - 0.0048 16.2 0.2 0.07 12.5 0.0 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EGG00693.1 - 0.0089 15.9 0.8 0.014 15.3 0.8 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGG00693.1 - 0.035 13.5 0.1 0.058 12.8 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Helicase_RecD PF05127.14 EGG00693.1 - 0.1 12.4 0.3 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Helicase Shikimate_DH PF01488.20 EGG00693.1 - 0.11 12.6 0.2 0.42 10.7 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Meth_synt_2 PF01717.18 EGG00694.1 - 3e-145 483.5 0.0 1e-141 471.9 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EGG00694.1 - 8.2e-107 357.3 0.0 2.6e-103 345.8 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EGG00694.1 - 1.6e-06 27.5 0.0 0.016 14.3 0.0 2.9 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) Fimbrial_K88 PF02432.15 EGG00694.1 - 0.12 12.4 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Fimbrial, major and minor subunit DUF4477 PF14780.6 EGG00695.1 - 0.057 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) PRANC PF09372.10 EGG00697.1 - 0.0021 18.4 6.0 0.0021 18.4 6.0 2.6 2 0 0 2 2 2 1 PRANC domain F-box-like PF12937.7 EGG00697.1 - 0.0065 16.3 0.0 0.029 14.2 0.0 2.2 1 1 0 1 1 1 1 F-box-like Choline_kin_N PF04428.14 EGG00697.1 - 0.0094 15.6 0.0 0.058 13.1 0.0 2.2 2 0 0 2 2 2 1 Choline kinase N terminus Bac_rhodopsin PF01036.18 EGG00698.1 - 8.1e-49 166.2 21.4 9.9e-49 165.9 21.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3792 PF12670.7 EGG00698.1 - 0.12 12.5 16.6 1.3 9.2 9.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) DUF575 PF04746.12 EGG00698.1 - 0.34 11.2 1.6 0.81 10.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF575) DUF2663 PF10864.8 EGG00698.1 - 0.96 9.9 5.5 6.5 7.2 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) zf-C2H2_aberr PF17017.5 EGG00699.1 - 0.0095 16.1 0.1 0.02 15.1 0.1 1.4 1 0 0 1 1 1 1 Aberrant zinc-finger zf-C2H2 PF00096.26 EGG00699.1 - 0.27 11.8 2.8 0.58 10.7 1.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Defensin_int PF17858.1 EGG00699.1 - 3 7.9 6.6 6.8 6.8 0.2 2.6 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide Frag1 PF10277.9 EGG00701.1 - 0.085 12.4 1.1 0.12 11.9 1.1 1.1 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Nuc_recep-AF1 PF11825.8 EGG00701.1 - 0.27 11.3 6.7 0.26 11.3 5.4 1.5 1 1 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 zf-C2H2 PF00096.26 EGG00702.1 - 1.4e-05 25.2 10.1 0.016 15.6 0.7 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EGG00702.1 - 0.0011 19.1 4.8 0.0075 16.4 0.3 2.4 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EGG00702.1 - 0.28 12.1 12.8 1.1 10.3 0.4 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger Podoplanin PF05808.11 EGG00704.1 - 7.9 6.6 9.6 48 4.0 7.7 2.7 2 1 0 2 2 2 0 Podoplanin Tubulin PF00091.25 EGG00705.1 - 2.5e-67 226.9 0.0 3.4e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGG00705.1 - 1.3e-48 164.3 0.0 2.4e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGG00705.1 - 0.00025 20.8 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGG00705.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Tubulin like PAS_9 PF13426.7 EGG00708.1 - 6.6e-06 26.3 0.0 0.0022 18.2 0.0 2.8 2 1 0 2 2 2 2 PAS domain 2OG-FeII_Oxy_2 PF13532.6 EGG00709.1 - 1.5e-20 74.2 0.0 2.4e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UBA PF00627.31 EGG00709.1 - 0.015 15.2 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 UBA/TS-N domain CUE PF02845.16 EGG00709.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 CUE domain Gti1_Pac2 PF09729.9 EGG00710.1 - 4.1e-35 121.5 1.6 4.7e-34 118.1 0.1 3.6 2 2 1 3 3 3 2 Gti1/Pac2 family zf-C2H2_11 PF16622.5 EGG00714.1 - 0.015 15.0 13.2 0.17 11.7 0.1 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 EGG00714.1 - 0.07 13.6 15.5 1.4 9.5 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type HMA PF00403.26 EGG00717.1 - 1.4e-13 51.0 1.4 1.7e-13 50.8 1.4 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain EIF_2_alpha PF07541.12 EGG00717.1 - 0.053 13.6 0.1 0.064 13.4 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Ribosomal_S21e PF01249.18 EGG00722.1 - 3e-39 133.0 0.0 3.3e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e GDC-P PF02347.16 EGG00725.1 - 2e-181 603.5 0.0 2.5e-170 567.0 0.0 2.5 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EGG00725.1 - 0.00016 20.8 0.1 0.00032 19.8 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGG00725.1 - 0.00064 19.1 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase RNase_Zc3h12a_2 PF14626.6 EGG00725.1 - 0.081 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain PPC PF04151.15 EGG00726.1 - 0.036 15.2 0.3 0.069 14.3 0.3 1.5 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain SNARE_assoc PF09335.11 EGG00727.1 - 3.8e-18 66.1 5.6 3.8e-18 66.1 5.6 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein ARL6IP6 PF15062.6 EGG00727.1 - 0.0048 17.0 0.2 0.017 15.2 0.2 2.0 1 0 0 1 1 1 1 Haemopoietic lineage transmembrane helix GILT PF03227.16 EGG00729.1 - 1.1e-16 60.9 0.7 1.9e-16 60.2 0.7 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_3 PF13192.6 EGG00729.1 - 0.12 12.4 0.2 0.25 11.4 0.2 1.5 1 0 0 1 1 1 0 Thioredoxin domain Spt4 PF06093.13 EGG00730.1 - 1.1e-31 108.7 0.2 1.3e-31 108.5 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Peptidase_A22B PF04258.13 EGG00731.1 - 4.5e-82 275.8 3.4 6.1e-82 275.3 3.4 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EGG00731.1 - 0.0003 20.4 0.6 0.0003 20.4 0.6 2.0 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease MerC PF03203.14 EGG00731.1 - 0.051 14.0 1.6 1.7 9.1 0.0 3.3 3 1 1 4 4 4 0 MerC mercury resistance protein CrgA PF06781.12 EGG00731.1 - 0.079 13.0 0.0 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 Cell division protein CrgA FAM176 PF14851.6 EGG00731.1 - 0.14 11.8 3.4 1.6 8.4 0.0 2.6 2 1 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 EGG00731.1 - 0.3 11.5 6.5 0.68 10.4 0.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Syntaxin-6_N PF09177.11 EGG00734.1 - 0.083 13.5 0.3 2.5 8.7 0.1 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Sad1_UNC PF07738.13 EGG00735.1 - 3.3e-28 98.3 0.0 7e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal NADHdeh_related PF10125.9 EGG00735.1 - 0.042 13.2 0.1 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 NADH dehydrogenase I, subunit N related protein TPR_19 PF14559.6 EGG00738.1 - 9.6e-06 26.0 0.0 0.15 12.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.31 EGG00738.1 - 0.0003 20.8 0.0 0.0011 19.0 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain ANAPC3 PF12895.7 EGG00738.1 - 0.0031 17.7 0.6 6 7.2 0.0 3.4 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EGG00738.1 - 0.45 11.5 2.5 20 6.4 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat ORC6 PF05460.13 EGG00739.1 - 2.5 7.3 5.9 2.9 7.1 5.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF775 PF05603.12 EGG00741.1 - 3.3e-49 167.2 1.4 3.8e-49 166.9 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Utp14 PF04615.13 EGG00743.1 - 6.7e-163 544.1 52.0 8.4e-163 543.8 52.0 1.1 1 0 0 1 1 1 1 Utp14 protein Adeno_E3 PF06040.11 EGG00743.1 - 9.8 6.4 6.1 9.5 6.4 0.4 3.1 3 0 0 3 3 3 0 Adenovirus E3 protein NPM1-C PF16276.5 EGG00744.1 - 0.12 12.3 0.3 1.1 9.3 0.2 2.2 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain SPATA3 PF15662.5 EGG00745.1 - 0.0024 18.6 7.0 0.0024 18.6 7.0 2.7 1 1 1 2 2 2 1 Spermatogenesis-associated protein 3 family Mitofilin PF09731.9 EGG00745.1 - 0.86 8.4 7.8 1.1 8.0 7.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF5437 PF17505.2 EGG00745.1 - 4.1 7.5 5.6 6.5 6.9 0.1 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5437) PAP2 PF01569.21 EGG00747.1 - 3.5e-22 78.6 2.3 3.5e-22 78.6 2.3 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EGG00747.1 - 0.6 9.8 10.7 0.85 9.3 1.1 2.8 2 1 0 2 2 2 0 PAP2 superfamily Ribosomal_L26 PF16906.5 EGG00748.1 - 5.9e-25 87.5 0.2 7.4e-25 87.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EGG00748.1 - 5.3e-08 32.5 4.2 5.3e-08 32.5 4.2 2.1 3 0 0 3 3 3 1 KOW motif zf-rbx1 PF12678.7 EGG00751.1 - 1.6e-13 50.7 2.6 3.3e-13 49.7 2.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGG00751.1 - 2.1e-08 34.4 14.7 2.3e-08 34.2 10.5 2.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGG00751.1 - 5.4e-08 32.6 0.8 1.4e-07 31.2 0.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG00751.1 - 6.2e-08 32.5 0.7 1.4e-07 31.4 0.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG00751.1 - 1.1e-06 28.3 5.4 3.8e-06 26.6 5.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG00751.1 - 8e-05 22.4 1.9 8e-05 22.4 1.9 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG00751.1 - 0.00019 21.3 4.0 0.0011 18.9 4.3 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGG00751.1 - 0.00023 20.8 3.4 0.0004 20.1 0.9 2.5 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGG00751.1 - 0.001 18.6 2.6 0.0031 17.1 2.6 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EGG00751.1 - 0.0016 18.4 5.3 0.0057 16.7 5.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGG00751.1 - 0.0019 18.0 5.1 0.0044 16.9 5.1 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGG00751.1 - 0.0039 17.3 1.5 0.011 15.9 1.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EGG00751.1 - 0.26 11.5 3.0 0.86 9.8 3.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EGG00751.1 - 0.48 10.8 4.0 0.98 9.8 4.0 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EGG00751.1 - 1.7 8.5 5.0 0.76 9.6 2.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RhoGEF PF00621.20 EGG00752.1 - 2.6e-25 89.7 0.0 4.1e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Glyco_transf_90 PF05686.12 EGG00753.1 - 2.6e-05 23.3 0.4 0.0011 18.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 PIR PF00399.19 EGG00753.1 - 2.9 7.6 4.7 3.6 7.2 0.7 2.3 2 0 0 2 2 2 0 Yeast PIR protein repeat Gln-synt_C PF00120.24 EGG00755.1 - 2.9e-59 200.8 0.0 3.7e-24 85.4 0.0 3.3 2 1 1 3 3 3 3 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 EGG00755.1 - 0.00046 20.0 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain DUF1018 PF06252.12 EGG00758.1 - 0.58 11.2 3.5 1.8 9.6 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1018) KDZ PF18758.1 EGG00759.1 - 3.2e-05 23.7 0.9 0.016 14.8 0.0 2.6 2 1 1 3 3 3 2 Kyakuja-Dileera-Zisupton transposase HP1451_C PF18472.1 EGG00759.1 - 0.026 14.5 0.0 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 HP1451 C-terminal domain Ferritin_2 PF13668.6 EGG00761.1 - 2.8e-29 102.0 1.3 3.9e-29 101.6 1.3 1.1 1 0 0 1 1 1 1 Ferritin-like domain Csm1 PF12539.8 EGG00762.1 - 9.6e-10 39.0 0.0 2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 TMCO5 PF14992.6 EGG00762.1 - 0.35 10.4 15.8 0.22 11.1 5.2 2.4 2 0 0 2 2 2 0 TMCO5 family Tli4_N PF18443.1 EGG00762.1 - 0.57 10.6 7.8 0.44 10.9 1.3 2.4 2 0 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain MRP-S26 PF14943.6 EGG00762.1 - 0.59 10.0 29.2 0.13 12.2 16.3 2.4 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 Cnn_1N PF07989.11 EGG00762.1 - 1.1 9.5 23.3 0.88 9.8 0.8 3.6 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Atg14 PF10186.9 EGG00762.1 - 2 7.4 26.1 12 4.9 3.7 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ax_dynein_light PF10211.9 EGG00762.1 - 6.5 6.6 24.8 0.63 10.0 2.3 3.0 2 1 1 3 3 3 0 Axonemal dynein light chain DUF2235 PF09994.9 EGG00763.1 - 4.4e-77 259.3 0.0 6.3e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Fungal_trans PF04082.18 EGG00764.1 - 2.8e-16 59.4 0.7 5.4e-16 58.4 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGG00764.1 - 0.00027 21.0 9.7 0.00049 20.2 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PriCT_1 PF08708.11 EGG00764.1 - 0.14 11.9 0.0 0.55 10.0 0.0 2.0 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) DUF3382 PF11862.8 EGG00764.1 - 0.22 11.8 0.0 0.51 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) ADK PF00406.22 EGG00765.1 - 1.9e-49 167.7 0.0 2.3e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGG00765.1 - 9.8e-38 129.7 0.0 1.3e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG00765.1 - 2.4e-12 47.5 0.0 3.4e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGG00765.1 - 4e-07 29.9 0.1 0.0067 16.1 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 EGG00765.1 - 7.7e-07 29.4 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGG00765.1 - 0.0082 15.4 0.0 0.012 14.8 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin Ploopntkinase3 PF18751.1 EGG00765.1 - 0.097 12.6 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 CxC5 PF18718.1 EGG00770.1 - 1.2e-28 99.5 8.0 2.6e-28 98.5 8.0 1.6 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG00770.1 - 3.1e-20 72.2 0.8 3.1e-20 72.2 0.8 2.8 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases GFA PF04828.14 EGG00770.1 - 0.038 14.3 0.6 1.4 9.3 0.3 2.5 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.6 EGG00770.1 - 0.15 12.6 2.9 0.2 12.2 1.3 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Porin_3 PF01459.22 EGG00772.1 - 1.1e-68 231.7 0.0 1.2e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF4131 PF13567.6 EGG00772.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) adh_short PF00106.25 EGG00774.1 - 2.3e-23 82.7 0.0 1.3e-18 67.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG00774.1 - 1.9e-12 47.3 0.0 1.1e-11 44.7 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG00774.1 - 0.00019 21.4 0.0 0.00028 20.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG00774.1 - 0.033 13.6 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Photo_RC PF00124.19 EGG00774.1 - 0.28 10.4 0.0 0.45 9.7 0.0 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre protein Lin-8 PF03353.15 EGG00776.1 - 0.1 12.1 6.0 0.13 11.8 6.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist adh_short PF00106.25 EGG00778.1 - 6.6e-28 97.5 0.0 2.4e-26 92.4 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG00778.1 - 1.1e-12 48.0 0.0 3.1e-11 43.3 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG00778.1 - 4.2e-06 26.8 0.0 6.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG00778.1 - 0.0035 16.8 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGG00778.1 - 0.079 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SF3A3 PF16837.5 EGG00778.1 - 0.088 13.3 0.0 0.3 11.6 0.0 2.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Pyr_redox_3 PF13738.6 EGG00778.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LacI PF00356.21 EGG00780.1 - 0.03 14.1 0.3 0.062 13.1 0.3 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Baculo_PEP_C PF04513.12 EGG00782.1 - 0.013 15.5 1.9 0.091 12.8 0.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EGG00782.1 - 0.042 14.3 3.1 2.1 8.9 0.5 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EGG00782.1 - 0.14 12.5 6.6 0.75 10.2 0.1 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Spore_III_AB PF09548.10 EGG00782.1 - 0.18 11.9 2.6 0.81 9.8 0.5 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) HOOK PF05622.12 EGG00782.1 - 0.21 9.7 11.9 0.077 11.1 5.6 2.1 2 0 0 2 2 2 0 HOOK protein WD40_alt PF14077.6 EGG00782.1 - 0.25 11.2 3.9 0.54 10.2 0.1 2.9 2 1 0 2 2 2 0 Alternative WD40 repeat motif LPP PF04728.13 EGG00782.1 - 0.29 11.6 2.5 0.86 10.0 0.2 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF4094 PF13334.6 EGG00782.1 - 0.57 10.6 8.3 1.8 9.0 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) Phage_GP20 PF06810.11 EGG00782.1 - 0.9 9.3 6.1 2.2 8.0 1.1 3.1 2 1 0 2 2 2 0 Phage minor structural protein GP20 SlyX PF04102.12 EGG00782.1 - 1.8 9.2 7.0 10 6.8 0.3 3.6 2 1 2 4 4 4 0 SlyX GAS PF13851.6 EGG00782.1 - 4.1 6.7 12.4 0.55 9.5 4.7 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 EGG00782.1 - 4.2 7.8 13.1 0.85 10.0 3.8 2.6 3 0 0 3 3 3 0 Fez1 Lzipper-MIP1 PF14389.6 EGG00782.1 - 8.9 6.7 11.3 2.9 8.2 8.2 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 CPSF100_C PF13299.6 EGG00785.1 - 1e-11 45.3 0.0 1.6e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal eRF1_2 PF03464.15 EGG00785.1 - 0.12 12.7 0.1 0.28 11.5 0.0 1.6 2 0 0 2 2 2 0 eRF1 domain 2 DUF1331 PF07048.11 EGG00787.1 - 1.3 8.7 3.4 3 7.6 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) DUF1744 PF08490.12 EGG00789.1 - 1.2e-131 439.0 0.8 1.7e-131 438.5 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EGG00789.1 - 9.1e-70 235.4 0.0 2.3e-69 234.1 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EGG00789.1 - 1.4e-13 50.4 0.6 1.1e-10 40.8 0.2 3.4 4 0 0 4 4 4 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EGG00789.1 - 1.3e-07 31.5 0.3 1.4e-06 28.2 0.3 2.4 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EGG00789.1 - 0.00017 21.6 0.0 0.00053 20.0 0.0 1.8 1 0 0 1 1 1 1 RNase_H superfamily DUF4379 PF14311.6 EGG00789.1 - 0.037 14.4 0.1 0.12 12.7 0.1 1.9 1 0 0 1 1 1 0 Probable Zinc-ribbon domain Flavi_glycop_C PF02832.16 EGG00789.1 - 0.18 12.0 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain Sld5 PF05916.11 EGG00792.1 - 3.3e-17 62.9 0.1 6.4e-17 62.0 0.0 1.5 1 1 0 1 1 1 1 GINS complex protein Kin17_mid PF10357.9 EGG00793.1 - 1.3e-48 164.1 0.5 1.3e-48 164.1 0.5 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 EGG00793.1 - 0.00061 20.1 6.8 0.0026 18.1 3.1 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGG00793.1 - 0.051 13.9 0.4 0.051 13.9 0.4 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGG00793.1 - 1.1 9.6 10.1 0.19 12.0 4.7 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding M157 PF11624.8 EGG00794.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 MHC class I-like protein M157 PRD PF00874.20 EGG00795.1 - 0.23 11.8 1.8 31 4.9 0.1 2.9 3 0 0 3 3 3 0 PRD domain DUF1264 PF06884.11 EGG00797.1 - 1.1e-40 139.0 0.9 1.4e-40 138.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) HsbA PF12296.8 EGG00801.1 - 0.22 12.0 3.3 2.1 8.8 0.5 2.1 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Alpha_kinase PF02816.18 EGG00802.1 - 2.5e-13 50.5 0.9 9.8e-13 48.6 0.9 2.0 1 1 0 1 1 1 1 Alpha-kinase family Ribosomal_S24e PF01282.19 EGG00803.1 - 2.6e-33 113.8 0.0 2.6e-33 113.8 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S24e ROS_MUCR PF05443.11 EGG00803.1 - 0.18 11.9 1.7 0.21 11.7 0.7 1.5 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein ECH_1 PF00378.20 EGG00804.1 - 1.1e-37 129.7 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGG00804.1 - 2e-14 53.8 0.0 4.8e-14 52.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UBX PF00789.20 EGG00805.1 - 2.5e-13 50.0 0.0 8.1e-13 48.4 0.0 1.9 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EGG00805.1 - 1.3e-09 37.7 0.1 2.6e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 EGG00805.1 - 0.00015 21.8 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like TAP_C PF03943.13 EGG00805.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain HGTP_anticodon2 PF12745.7 EGG00805.1 - 7.6 6.0 12.7 2.3 7.7 6.0 2.5 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs MLD PF11647.8 EGG00807.1 - 0.005 17.1 0.8 0.019 15.2 0.1 2.3 2 0 0 2 2 2 1 Membrane Localization Domain DUF4460 PF14687.6 EGG00807.1 - 5.3 7.1 7.1 18 5.4 3.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4460) Pet100 PF09803.9 EGG00809.1 - 9.3e-25 87.0 0.7 1.2e-24 86.6 0.7 1.1 1 0 0 1 1 1 1 Pet100 Yop-YscD_ppl PF16693.5 EGG00810.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Inner membrane component of T3SS, periplasmic domain VHS PF00790.19 EGG00811.1 - 9.1e-36 122.8 0.0 2.4e-35 121.4 0.0 1.8 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EGG00811.1 - 1.6e-18 66.8 2.0 2.7e-18 66.1 0.2 2.3 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 EGG00811.1 - 0.0069 16.0 0.2 0.089 12.4 0.1 2.5 2 0 0 2 2 2 1 GGA N-GAT domain Ribosomal_L17 PF01196.19 EGG00811.1 - 0.051 14.5 0.3 0.3 12.0 0.0 2.2 3 0 0 3 3 3 0 Ribosomal protein L17 Exonuc_VII_L PF02601.15 EGG00811.1 - 0.21 11.1 3.6 0.53 9.8 3.6 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit EF-hand_7 PF13499.6 EGG00813.1 - 0.077 13.5 1.5 0.15 12.5 0.2 2.2 2 0 0 2 2 2 0 EF-hand domain pair Elong_Iki1 PF10483.9 EGG00813.1 - 0.1 12.1 5.2 0.82 9.1 0.4 2.1 2 0 0 2 2 2 0 Elongator subunit Iki1 DUF3306 PF11748.8 EGG00813.1 - 1.9 9.4 7.3 14 6.5 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) PP1c_bdg PF10488.9 EGG00814.1 - 0.0013 18.3 5.4 0.0025 17.3 5.4 1.4 1 0 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region Cwf_Cwc_15 PF04889.12 EGG00814.1 - 2 8.1 8.1 6.3 6.4 6.5 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Hema_stalk PF08720.10 EGG00815.1 - 0.0026 17.5 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Influenza C hemagglutinin stalk DnaJ-X PF14308.6 EGG00816.1 - 0.06 12.8 1.2 0.11 12.0 1.1 1.5 1 1 0 1 1 1 0 X-domain of DnaJ-containing KDZ PF18758.1 EGG00817.1 - 4.3e-43 147.5 1.5 9.9e-43 146.3 1.5 1.6 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGG00817.1 - 2.9e-26 91.6 0.1 6.6e-26 90.5 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG00817.1 - 4.1e-09 36.5 0.0 8.7e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG00817.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Dpoe2NT PF12213.8 EGG00817.1 - 0.094 13.0 0.1 27 5.1 0.0 3.0 3 0 0 3 3 3 0 DNA polymerases epsilon N terminal DUF3819 PF12842.7 EGG00819.1 - 3.4e-06 27.1 0.0 4.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) PBP_sp32 PF07222.12 EGG00821.1 - 0.11 12.0 1.0 0.16 11.4 1.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pmp3 PF01679.17 EGG00822.1 - 1.3e-22 79.7 7.9 1.5e-22 79.5 7.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1056 PF06341.11 EGG00822.1 - 0.004 17.4 0.1 0.0052 17.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1056) Pmp3 PF01679.17 EGG00824.1 - 2.1e-21 75.8 10.0 2.6e-21 75.6 10.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Synaptobrevin PF00957.21 EGG00825.1 - 1.6e-30 104.7 0.1 1.9e-30 104.5 0.1 1.0 1 0 0 1 1 1 1 Synaptobrevin C_Hendra PF16821.5 EGG00825.1 - 0.0054 16.6 0.1 0.0063 16.4 0.1 1.0 1 0 0 1 1 1 1 C protein from hendra and measles viruses MCU PF04678.13 EGG00825.1 - 0.081 13.0 0.0 0.092 12.8 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter PsbI PF02532.14 EGG00825.1 - 1.6 8.7 4.4 2.2 8.3 4.4 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Nodulin_late PF07127.11 EGG00827.1 - 2.4 8.6 10.0 0.36 11.2 1.1 2.9 2 2 1 3 3 3 0 Late nodulin protein F-box PF00646.33 EGG00828.1 - 0.0032 17.3 1.0 0.21 11.5 0.1 3.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EGG00828.1 - 0.06 13.3 0.8 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 F-box-like DUF4703 PF15775.5 EGG00828.1 - 0.092 12.5 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) SPX PF03105.19 EGG00829.1 - 8 6.3 19.1 11 5.9 19.1 1.1 1 0 0 1 1 1 0 SPX domain Hydrolase_4 PF12146.8 EGG00830.1 - 1.4e-30 106.4 0.0 2.3e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG00830.1 - 4e-07 30.9 0.0 6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG00830.1 - 4e-07 29.9 0.4 2e-06 27.6 0.5 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 EGG00830.1 - 0.015 14.9 0.2 0.038 13.6 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 EGG00830.1 - 0.074 12.5 0.0 3 7.2 0.0 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family Asp2 PF16929.5 EGG00830.1 - 0.2 10.6 0.0 0.28 10.1 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter PGAP1 PF07819.13 EGG00831.1 - 3.3e-08 33.5 0.0 5.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 EGG00831.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EGG00831.1 - 1.9e-05 24.4 0.0 0.00022 20.9 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 EGG00831.1 - 2.7e-05 23.8 0.0 7.2e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EGG00831.1 - 0.00039 21.1 0.0 0.00051 20.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 EGG00831.1 - 0.0048 16.3 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 EGG00831.1 - 0.0055 15.9 0.0 0.0083 15.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 EGG00831.1 - 0.029 14.5 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 EGG00831.1 - 0.042 13.5 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 EGG00831.1 - 0.053 12.8 0.1 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EGG00831.1 - 0.21 11.4 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family MBOAT_2 PF13813.6 EGG00833.1 - 4.8e-16 58.8 0.6 1.4e-15 57.3 0.1 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Bac_surface_Ag PF01103.23 EGG00834.1 - 3e-37 128.9 1.4 5.2e-37 128.1 0.3 1.7 1 1 0 2 2 2 1 Surface antigen RabGAP-TBC PF00566.18 EGG00835.1 - 5.7e-29 101.3 0.1 1e-28 100.5 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EGG00835.1 - 1.7e-05 24.4 0.0 0.0001 21.8 0.0 2.1 2 0 0 2 2 2 1 Rab-binding domain (RBD) Pyridoxal_deC PF00282.19 EGG00836.1 - 2.2e-62 210.9 0.0 3.1e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGG00836.1 - 0.0019 17.2 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Mlh1_C PF16413.5 EGG00837.1 - 1.4e-77 260.7 2.5 1.4e-77 260.7 2.5 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EGG00837.1 - 2.6e-27 94.9 0.0 4.8e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EGG00837.1 - 1.4e-14 54.1 0.1 3.4e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGG00837.1 - 2.7e-07 31.1 0.0 6.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HD_assoc PF13286.6 EGG00837.1 - 0.027 15.0 0.0 0.11 13.0 0.0 2.0 1 0 0 1 1 1 0 Phosphohydrolase-associated domain Bestrophin PF01062.21 EGG00840.1 - 1.7e-33 116.3 0.1 2.4e-20 73.1 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel FUSC PF04632.12 EGG00840.1 - 0.014 14.0 0.4 0.014 14.0 0.4 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Bestrophin PF01062.21 EGG00843.1 - 1.9e-32 112.9 0.0 2.1e-21 76.6 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF4293 PF14126.6 EGG00843.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Bestrophin PF01062.21 EGG00844.1 - 3.4e-19 69.3 1.0 4.5e-19 68.9 1.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Alpha_kinase PF02816.18 EGG00845.1 - 1.7e-31 109.8 0.1 2.1e-31 109.5 0.1 1.1 1 0 0 1 1 1 1 Alpha-kinase family Bestrophin PF01062.21 EGG00846.1 - 1.4e-26 93.5 0.5 5.6e-18 65.4 1.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel EFG_C PF00679.24 EGG00849.1 - 1.7e-07 31.2 0.0 1.7e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Elongation factor G C-terminus Nop10p PF04135.12 EGG00851.1 - 2.5e-22 78.7 0.2 2.9e-22 78.5 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family GCM PF03615.15 EGG00853.1 - 7.7e-05 22.6 3.0 0.00012 22.0 0.9 2.2 2 0 0 2 2 2 1 GCM motif protein PTPlike_phytase PF14566.6 EGG00853.1 - 0.059 13.5 0.1 0.76 9.9 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate Mif2_N PF15624.6 EGG00853.1 - 0.52 11.0 5.2 1.3 9.7 5.2 1.7 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal zf-C2H2_8 PF15909.5 EGG00854.1 - 0.081 13.2 0.3 0.18 12.2 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon rRNA_proc-arch PF13234.6 EGG00855.1 - 3.2e-81 273.2 0.2 2.1e-80 270.5 0.0 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 EGG00855.1 - 2.8e-53 179.9 1.0 5.7e-53 178.9 1.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EGG00855.1 - 2.5e-18 66.5 0.0 8.3e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG00855.1 - 2.6e-07 31.0 0.0 1.6e-06 28.4 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG00855.1 - 0.00012 22.1 0.0 0.00039 20.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGG00855.1 - 0.0038 17.5 0.0 1.1 9.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EGG00855.1 - 0.01 15.8 1.0 3.7 7.4 0.0 2.6 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea ATPase PF06745.13 EGG00855.1 - 0.021 14.2 0.0 5.8 6.2 0.0 2.5 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 EGG00855.1 - 0.042 12.9 0.0 0.087 11.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein HEPN_AbiU2 PF18734.1 EGG00855.1 - 0.45 10.0 4.9 0.56 9.7 1.0 2.3 2 0 0 2 2 2 0 AbiU2 Acetyltransf_1 PF00583.25 EGG00856.1 - 6.8e-11 42.4 0.0 8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG00856.1 - 2.1e-07 30.9 0.0 5.4e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG00856.1 - 8.3e-05 22.9 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGG00856.1 - 0.00034 20.7 0.0 0.00076 19.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain IreB PF06135.12 EGG00856.1 - 0.033 14.4 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 IreB regulatory phosphoprotein HK PF02110.15 EGG00856.1 - 0.037 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Adaptin_binding PF10199.9 EGG00858.1 - 0.14 12.7 13.6 1.3 9.6 13.7 2.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 RPN1_RPN2_N PF17781.1 EGG00859.1 - 5.7e-120 400.4 1.4 1e-119 399.5 1.4 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EGG00859.1 - 1.1e-27 95.8 0.0 2.3e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EGG00859.1 - 1.3e-19 69.5 23.4 7.5e-05 23.0 0.0 8.6 9 0 0 9 9 9 6 Proteasome/cyclosome repeat zf-C4H2 PF10146.9 EGG00859.1 - 9 6.5 11.6 0.28 11.5 3.1 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein RHD3 PF05879.12 EGG00861.1 - 1.3e-36 126.1 0.7 1.4e-23 83.1 0.0 2.1 2 0 0 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 EGG00861.1 - 0.00034 20.7 0.0 0.00052 20.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGG00861.1 - 0.0068 16.5 0.5 0.012 15.7 0.3 1.5 1 1 0 1 1 1 1 Dynamin family GATase_7 PF13537.6 EGG00861.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain MFS_1 PF07690.16 EGG00863.1 - 2.6e-30 105.5 25.5 3.2e-30 105.2 25.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 EGG00864.1 - 4.7e-21 75.1 31.3 1.7e-20 73.3 30.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily AbiJ_NTD4 PF18863.1 EGG00865.1 - 0.072 13.6 0.6 0.14 12.6 0.6 1.5 1 1 0 1 1 1 0 AbiJ N-terminal domain 4 COMM_domain PF07258.14 EGG00868.1 - 0.22 11.7 0.1 0.39 10.8 0.1 1.3 1 0 0 1 1 1 0 COMM domain TRF PF08558.10 EGG00868.1 - 0.22 11.1 0.0 1.7 8.2 0.0 1.9 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) Phage_int_SAM_4 PF13495.6 EGG00869.1 - 0.05 14.1 0.1 0.47 10.9 0.0 2.7 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain HP0268 PF18618.1 EGG00869.1 - 0.24 11.8 0.2 0.54 10.7 0.2 1.5 1 0 0 1 1 1 0 HP0268 Glyco_transf_88 PF16849.5 EGG00872.1 - 0.0066 15.4 0.8 0.0086 15.0 0.8 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 88 DUF5403 PF17395.2 EGG00872.1 - 0.34 11.2 3.4 11 6.4 0.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5403) PI3K_1B_p101 PF10486.9 EGG00874.1 - 8.4 4.0 35.5 12 3.6 35.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ABC_tran_CTD PF16326.5 EGG00878.1 - 0.11 12.7 1.7 0.54 10.5 0.1 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF702 PF05142.12 EGG00880.1 - 3.6 8.1 5.8 7.6 7.0 5.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Spc7 PF08317.11 EGG00882.1 - 0.04 12.8 0.6 0.06 12.2 0.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.5 EGG00882.1 - 0.084 13.2 3.9 0.13 12.5 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Vip3A_N PF12495.8 EGG00882.1 - 0.092 12.6 0.3 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal TolA_bind_tri PF16331.5 EGG00882.1 - 0.27 11.3 1.8 2.8 8.1 0.0 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF2477 PF10631.9 EGG00883.1 - 0.15 12.7 4.2 5.9 7.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) NUP50 PF08911.11 EGG00885.1 - 7.1e-13 49.0 0.9 7.1e-13 49.0 0.9 4.4 5 0 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 EGG00885.1 - 2.2e-09 37.6 0.7 5.8e-09 36.3 0.7 1.7 1 0 0 1 1 1 1 RanBP1 domain PMAIP1 PF15150.6 EGG00886.1 - 6.4 6.7 18.0 2.3 8.2 0.3 4.9 5 0 0 5 5 5 0 Phorbol-12-myristate-13-acetate-induced PA_decarbox PF05870.11 EGG00891.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) DUF3943 PF13084.6 EGG00892.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) Peptidase_M50B PF13398.6 EGG00893.1 - 5.8e-56 189.3 14.6 7.2e-56 189.0 14.6 1.1 1 0 0 1 1 1 1 Peptidase M50B-like DUF4040 PF13244.6 EGG00893.1 - 0.0013 18.8 0.9 0.0055 16.8 0.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4040) GTP1_OBG PF01018.22 EGG00895.1 - 2.6e-40 137.6 6.3 3.4e-40 137.2 6.3 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 EGG00895.1 - 1.4e-18 67.0 0.0 2.4e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG00895.1 - 1.9e-05 24.3 0.0 8.8e-05 22.1 0.0 2.0 2 1 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 EGG00895.1 - 0.00098 18.6 0.2 0.32 10.4 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGG00895.1 - 0.0058 16.8 0.0 4.9 7.4 0.0 2.4 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EGG00895.1 - 0.06 12.9 0.0 0.75 9.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EGG00895.1 - 0.064 12.2 0.0 0.16 10.9 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB LRR_4 PF12799.7 EGG00896.1 - 0.00058 20.2 0.7 0.041 14.3 0.1 2.9 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGG00896.1 - 0.0091 15.9 0.4 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 EGG00896.1 - 0.45 10.3 2.6 2.3 8.1 0.5 2.9 2 1 0 2 2 2 0 Leucine rich repeat AAA_assoc PF14363.6 EGG00897.1 - 0.045 14.1 0.0 0.066 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA 2-Hacid_dh_C PF02826.19 EGG00899.1 - 7.7e-51 172.0 0.0 1.1e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGG00899.1 - 1.9e-16 59.9 0.0 2.4e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGG00899.1 - 0.0011 19.1 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase LRR_6 PF13516.6 EGG00900.1 - 1.2e-08 34.3 11.3 0.0068 16.4 0.3 5.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 EGG00900.1 - 9.3e-08 32.3 21.5 0.00081 19.7 3.5 4.5 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG00900.1 - 0.012 15.4 20.9 0.091 12.5 3.4 3.6 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 EGG00900.1 - 0.096 13.3 15.4 13 6.8 0.1 6.6 3 2 2 5 5 5 0 Leucine Rich Repeat LRR_9 PF14580.6 EGG00900.1 - 0.7 9.4 3.8 1.7 8.1 3.4 1.8 1 1 0 1 1 1 0 Leucine-rich repeat adh_short_C2 PF13561.6 EGG00901.1 - 1.4e-41 142.6 0.0 1.6e-38 132.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG00901.1 - 2.3e-31 108.8 0.1 2.6e-28 98.8 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG00901.1 - 0.011 15.6 0.1 0.032 14.1 0.1 1.7 1 1 0 1 1 1 0 KR domain DUF1776 PF08643.10 EGG00901.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Zip PF02535.22 EGG00902.1 - 6.8e-58 196.5 8.3 1e-57 195.9 8.3 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Metallophos PF00149.28 EGG00904.1 - 3.4e-40 138.7 0.1 4.5e-40 138.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGG00904.1 - 2.1e-21 76.1 1.1 4e-21 75.2 0.6 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DUF948 PF06103.11 EGG00906.1 - 0.0067 16.7 1.9 0.018 15.3 1.9 1.7 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) BORCS7 PF16088.5 EGG00906.1 - 0.036 14.3 2.2 0.097 12.9 2.2 1.7 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 Glyco_hydro_85 PF03644.13 EGG00909.1 - 5.4e-30 104.8 0.8 8.8e-30 104.1 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Rhodanese_C PF12368.8 EGG00910.1 - 7.5 7.0 11.5 15 6.1 1.7 2.4 1 1 1 2 2 2 0 Rhodanase C-terminal Acetyltransf_1 PF00583.25 EGG00911.1 - 6e-13 49.1 0.0 7.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG00911.1 - 1.5e-09 38.1 0.0 2.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG00911.1 - 8.6e-07 28.9 0.0 2.2e-06 27.6 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG00911.1 - 0.0057 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PX PF00787.24 EGG00912.1 - 1.2e-18 67.1 0.5 3.8e-18 65.5 0.1 2.1 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 EGG00912.1 - 0.0013 18.2 1.5 0.019 14.4 1.2 2.6 2 1 1 3 3 3 1 WASP-binding domain of Sorting nexin protein WXG100 PF06013.12 EGG00912.1 - 0.058 13.6 0.5 0.26 11.5 0.1 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Myb_DNA-binding PF00249.31 EGG00914.1 - 1.7e-17 63.3 10.8 3.5e-10 39.9 0.2 3.2 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG00914.1 - 4.3e-16 58.9 4.6 2.1e-10 40.7 0.3 3.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Cupin_1 PF00190.22 EGG00915.1 - 7.8e-31 106.7 0.1 3.6e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EGG00915.1 - 9e-21 73.4 0.3 1.6e-11 43.7 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EGG00915.1 - 0.0015 18.2 0.0 0.23 11.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 EGG00915.1 - 0.009 15.9 0.0 3.7 7.4 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase Ectoine_synth PF06339.12 EGG00915.1 - 0.037 14.2 0.0 1.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Ectoine synthase PCO_ADO PF07847.12 EGG00915.1 - 0.13 11.7 1.3 17 4.8 0.0 3.3 2 1 1 3 3 3 0 PCO_ADO DUF1431 PF07248.12 EGG00917.1 - 0.0057 16.9 0.1 0.008 16.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1431) ACBP PF00887.19 EGG00918.1 - 8.2e-27 93.3 0.1 1.1e-26 92.9 0.1 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Tox-REase-5 PF15648.6 EGG00918.1 - 0.00037 20.9 0.2 0.00045 20.7 0.2 1.2 1 0 0 1 1 1 1 Restriction endonuclease fold toxin 5 NIF PF03031.18 EGG00919.1 - 2.3e-07 30.7 4.9 0.018 14.8 0.3 3.8 2 2 1 3 3 3 2 NLI interacting factor-like phosphatase TetR_C_19 PF17924.1 EGG00919.1 - 0.63 10.6 3.8 1.8 9.2 1.1 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Syntaxin-6_N PF09177.11 EGG00920.1 - 1.8e-10 41.3 0.7 6.5e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal ANAPC15 PF15243.6 EGG00920.1 - 0.027 14.9 1.9 0.042 14.2 1.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 AnfO_nitrog PF09582.10 EGG00920.1 - 0.046 13.0 0.3 0.059 12.7 0.3 1.2 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) WD40_4 PF16300.5 EGG00921.1 - 8.8e-28 95.9 0.2 8.6e-15 54.4 0.2 2.8 2 0 0 2 2 2 2 Type of WD40 repeat ANAPC4_WD40 PF12894.7 EGG00921.1 - 4.5e-06 26.9 0.0 0.31 11.4 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 EGG00921.1 - 0.0002 21.1 0.0 0.00051 19.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 EGG00921.1 - 0.0011 19.8 14.2 0.33 11.9 2.8 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat Alpha-amyl_C PF09071.10 EGG00921.1 - 0.098 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Alpha-amylase, C terminal Cyt-b5 PF00173.28 EGG00923.1 - 1.6e-11 44.2 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ADH_N PF08240.12 EGG00924.1 - 7.4e-22 77.3 0.3 1.3e-21 76.6 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGG00924.1 - 1.5e-14 54.1 0.0 2.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGG00924.1 - 2.1e-07 30.6 0.0 5.3e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ThiF PF00899.21 EGG00924.1 - 0.0034 16.8 0.1 0.0055 16.1 0.1 1.3 1 0 0 1 1 1 1 ThiF family Pyr_redox_2 PF07992.14 EGG00924.1 - 0.026 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EGG00924.1 - 0.031 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Spermine_synth PF01564.17 EGG00924.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Med26 PF08711.11 EGG00925.1 - 8.5e-11 41.7 0.1 2e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TAF8_C PF10406.9 EGG00926.1 - 9.1e-05 22.9 6.2 0.00027 21.4 0.8 2.9 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 EGG00926.1 - 0.00059 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Corazonin PF17308.2 EGG00926.1 - 0.062 13.7 0.3 0.062 13.7 0.3 2.1 2 1 0 2 2 2 0 Pro-corazonin RabGAP-TBC PF00566.18 EGG00927.1 - 5.2e-36 124.3 1.4 6.4e-36 124.0 1.4 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 4HBT PF03061.22 EGG00928.1 - 4.7e-08 33.3 0.0 1.6e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 Thioesterase superfamily M20_dimer PF07687.14 EGG00930.1 - 1.4e-11 44.2 0.1 2.5e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EGG00930.1 - 1.9e-06 27.7 0.1 3.1e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Dus PF01207.17 EGG00933.1 - 2.8e-38 131.8 0.0 3.5e-37 128.2 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EGG00933.1 - 1.6e-05 24.5 0.0 3.4e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.21 EGG00933.1 - 0.00028 20.2 0.0 0.39 9.9 0.0 2.2 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase IMPDH PF00478.25 EGG00933.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EGG00933.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase TMP-TENI PF02581.17 EGG00933.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 1 0 1 1 1 0 Thiamine monophosphate synthase IGPS PF00218.21 EGG00933.1 - 0.21 10.7 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase EAV_GP5 PF15981.5 EGG00934.1 - 0.7 10.3 4.1 0.29 11.6 0.7 1.9 2 0 0 2 2 2 0 Envelope glycoprotein GP 5 of equine arteritis virus EMP24_GP25L PF01105.24 EGG00937.1 - 9.6e-41 139.7 0.1 1.1e-40 139.5 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kelch_5 PF13854.6 EGG00938.1 - 5.9e-12 45.3 6.9 1.9e-09 37.3 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EGG00938.1 - 2.5e-10 40.4 13.1 3e-05 24.2 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EGG00938.1 - 6.4e-05 22.9 12.3 0.27 11.3 0.1 6.2 5 1 1 6 6 6 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EGG00938.1 - 0.00028 21.1 13.8 2.9 8.3 0.2 6.6 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 EGG00938.1 - 0.0056 16.6 12.2 0.069 13.1 0.6 5.4 5 1 0 5 5 5 1 Kelch motif Amnionless PF14828.6 EGG00938.1 - 0.028 13.3 0.1 0.14 10.9 0.0 1.9 2 0 0 2 2 2 0 Amnionless Kelch_1 PF01344.25 EGG00938.1 - 0.066 12.8 15.4 2 8.0 0.0 5.7 6 0 0 6 6 6 0 Kelch motif Yip1 PF04893.17 EGG00938.1 - 0.087 12.5 0.1 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Yip1 domain TauE PF01925.19 EGG00938.1 - 0.34 10.5 3.1 0.35 10.5 0.2 2.4 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE TPR_8 PF13181.6 EGG00939.1 - 1.8e-06 27.7 2.4 0.083 13.2 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG00939.1 - 4.6e-06 26.3 7.3 0.0035 17.3 0.0 4.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG00939.1 - 5.2e-06 26.8 1.3 0.0031 18.2 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG00939.1 - 1.3e-05 25.6 1.1 0.00018 21.9 0.1 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG00939.1 - 1.6e-05 25.5 0.0 0.0095 16.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG00939.1 - 0.00011 21.9 2.4 0.032 14.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGG00939.1 - 0.00019 20.7 0.1 0.00053 19.3 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG00939.1 - 0.00029 21.0 0.1 0.21 12.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG00939.1 - 0.0006 20.3 3.2 0.65 10.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG00939.1 - 0.0012 19.0 1.8 0.08 13.2 0.1 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGG00939.1 - 0.0017 18.6 2.2 0.066 13.5 2.6 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG00939.1 - 0.0024 17.8 5.5 0.22 11.6 0.3 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat USP8_dimer PF08969.11 EGG00939.1 - 0.0052 17.0 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 USP8 dimerisation domain Nro1 PF12753.7 EGG00939.1 - 0.0068 15.4 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 HECT_2 PF09814.9 EGG00940.1 - 1.8e-12 46.8 0.0 3.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding PITH PF06201.13 EGG00941.1 - 4.4e-37 127.6 0.0 5.3e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain zinc_ribbon_10 PF10058.9 EGG00942.1 - 2e-19 69.0 0.2 3.3e-19 68.4 0.2 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Mu-like_Com PF10122.9 EGG00942.1 - 0.0002 20.7 0.1 0.0004 19.8 0.1 1.5 1 0 0 1 1 1 1 Mu-like prophage protein Com Utp12 PF04003.12 EGG00942.1 - 0.18 12.1 1.4 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Dip2/Utp12 Family DUF3810 PF12725.7 EGG00942.1 - 0.48 9.7 3.1 1.1 8.5 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) TMF_DNA_bd PF12329.8 EGG00942.1 - 1.3 9.1 15.5 4 7.5 0.9 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding P4Ha_N PF08336.11 EGG00942.1 - 2.6 8.1 9.0 0.47 10.5 0.9 2.3 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region XhlA PF10779.9 EGG00942.1 - 4.3 7.6 5.8 4.2 7.6 0.6 2.3 2 0 0 2 2 2 0 Haemolysin XhlA PLAC8 PF04749.17 EGG00943.1 - 4.8e-17 62.8 4.3 7.4e-17 62.2 4.3 1.2 1 0 0 1 1 1 1 PLAC8 family UCH PF00443.29 EGG00944.1 - 1.4e-81 273.8 0.7 3.6e-40 138.1 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG00944.1 - 6.7e-36 124.5 8.1 1.8e-16 60.7 1.9 4.2 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EGG00944.1 - 1.2e-07 31.5 9.2 0.0027 17.2 1.8 4.2 2 2 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3648 PF12364.8 EGG00944.1 - 0.023 14.9 0.1 0.071 13.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) Josephin PF02099.17 EGG00944.1 - 0.077 13.1 1.0 3.9 7.5 0.1 2.6 2 0 0 2 2 2 0 Josephin DNApol_Exo PF18136.1 EGG00945.1 - 2.5e-96 322.1 0.0 4.2e-96 321.4 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EGG00945.1 - 1.8e-44 152.3 0.0 3e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A zf-C2H2_jaz PF12171.8 EGG00946.1 - 0.0003 21.0 0.1 0.00066 19.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Noggin PF05806.12 EGG00946.1 - 0.1 12.5 2.3 0.16 11.9 2.0 1.4 1 1 0 1 1 1 0 Noggin zf-met PF12874.7 EGG00946.1 - 0.11 12.9 0.2 0.23 11.9 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGG00947.1 - 0.00073 19.8 0.2 0.0016 18.7 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Noggin PF05806.12 EGG00947.1 - 0.1 12.5 3.1 0.13 12.1 2.6 1.4 1 1 0 1 1 1 0 Noggin zf-met PF12874.7 EGG00947.1 - 0.12 12.8 0.3 0.26 11.7 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Polysacc_deac_1 PF01522.21 EGG00948.1 - 7.2e-17 61.4 0.0 1.1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Mucin PF01456.17 EGG00948.1 - 0.077 13.0 8.6 0.17 11.9 8.6 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein PH_9 PF15410.6 EGG00949.1 - 3e-05 24.4 0.0 0.0001 22.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGG00949.1 - 0.0046 17.4 0.0 0.064 13.8 0.0 2.6 1 1 0 1 1 1 1 PH domain Brix PF04427.18 EGG00951.1 - 1.1e-34 120.2 0.2 1.7e-34 119.6 0.2 1.3 1 0 0 1 1 1 1 Brix domain A_deaminase PF00962.22 EGG00953.1 - 6e-113 377.5 0.0 1.7e-112 376.0 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase SSP160 PF06933.11 EGG00954.1 - 0.065 11.4 15.7 0.18 10.0 15.7 1.7 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Nup96 PF12110.8 EGG00956.1 - 5.2e-89 298.2 0.0 7.6e-89 297.7 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EGG00956.1 - 9.8e-52 175.0 0.0 1.8e-51 174.2 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EGG00956.1 - 2e-26 92.6 285.2 2.1e-11 44.5 34.7 10.8 4 2 6 10 10 10 7 Nucleoporin FG repeat region DUF5470 PF17564.2 EGG00957.1 - 0.069 13.4 0.3 0.069 13.4 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5470) RCR PF12273.8 EGG00958.1 - 2.5 8.8 25.9 15 6.2 25.9 2.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red PTN13_u3 PF16599.5 EGG00959.1 - 0.02 15.0 3.1 0.032 14.3 3.1 1.3 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ RRF PF01765.19 EGG00960.1 - 0.041 13.8 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 Ribosome recycling factor SAM_2 PF07647.17 EGG00962.1 - 2.2e-07 30.9 0.0 3.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGG00962.1 - 8.1e-05 23.0 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 EGG00962.1 - 0.41 10.9 2.1 0.36 11.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) Glyco_hydro_18 PF00704.28 EGG00963.1 - 2.4e-55 188.4 0.2 3.1e-55 188.1 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 EGG00963.1 - 0.0085 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Tim54 PF11711.8 EGG00965.1 - 2 7.1 4.0 3 6.5 4.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Antimicrobial25 PF16839.5 EGG00967.1 - 0.43 10.7 8.6 0.1 12.7 1.4 2.6 2 1 0 2 2 2 0 Nematode antimicrobial peptide HnRNPA1 PF11627.8 EGG00967.1 - 2.8 8.2 11.0 17 5.7 6.6 2.4 1 1 1 2 2 2 0 Nuclear factor hnRNPA1 ATG11 PF10377.9 EGG00969.1 - 5.8e-33 113.7 0.0 5.8e-33 113.7 0.0 2.9 3 0 0 3 3 3 1 Autophagy-related protein 11 APG17 PF04108.12 EGG00969.1 - 2.5e-07 30.2 0.6 2.5e-07 30.2 0.6 4.4 2 2 2 4 4 4 2 Autophagy protein Apg17 FPP PF05911.11 EGG00969.1 - 0.61 8.2 49.8 0.081 11.1 18.7 2.4 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil WD40_alt PF14077.6 EGG00969.1 - 2.7 7.9 5.8 28 4.6 0.4 3.2 3 0 0 3 3 3 0 Alternative WD40 repeat motif ERM PF00769.19 EGG00969.1 - 3.8 7.3 55.9 0.98 9.2 37.3 3.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DOPA_dioxygen PF08883.11 EGG00971.1 - 0.82 9.9 15.9 3.7 7.8 0.6 5.6 1 1 7 8 8 8 0 Dopa 4,5-dioxygenase family UIM PF02809.20 EGG00973.1 - 0.051 13.5 0.9 0.19 11.7 0.9 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF416 PF04222.12 EGG00973.1 - 1.3 8.4 7.0 0.71 9.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF416) Met_10 PF02475.16 EGG00974.1 - 6.7e-55 185.9 0.0 1e-54 185.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 EGG00974.1 - 2.5e-06 26.9 0.0 4.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 EGG00974.1 - 0.00047 19.6 0.0 0.0008 18.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EGG00974.1 - 0.0022 17.6 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 EGG00974.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 EGG00974.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 EGG00974.1 - 0.026 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Retrotran_gag_2 PF14223.6 EGG00976.1 - 0.021 14.5 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type QRPTase_C PF01729.19 EGG00977.1 - 1.9e-55 187.2 0.0 2.3e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EGG00977.1 - 4e-18 65.3 0.0 1.2e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain TMP-TENI PF02581.17 EGG00977.1 - 0.013 14.8 0.0 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 Thiamine monophosphate synthase Ribul_P_3_epim PF00834.19 EGG00977.1 - 0.059 12.7 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 Ribulose-phosphate 3 epimerase family PcrB PF01884.17 EGG00977.1 - 0.062 12.7 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 PcrB family IGPS PF00218.21 EGG00977.1 - 0.063 12.4 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Alginate_lyase PF05426.12 EGG00978.1 - 0.056 13.0 0.1 0.064 12.8 0.1 1.1 1 0 0 1 1 1 0 Alginate lyase RSN1_7TM PF02714.15 EGG00979.1 - 1.3e-79 267.4 25.1 2.3e-79 266.5 25.1 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGG00979.1 - 3.5e-43 147.1 0.7 1.1e-42 145.4 0.7 2.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGG00979.1 - 1.7e-35 122.9 0.0 3.3e-35 121.9 0.0 1.5 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EGG00979.1 - 6.6e-11 42.2 0.0 2.2e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter HAD PF12710.7 EGG00980.1 - 2.3e-24 86.8 0.0 3e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG00980.1 - 4.7e-05 23.8 0.8 0.0032 17.8 0.8 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGG00980.1 - 5.7e-05 23.3 0.0 0.0049 17.0 0.1 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EGG00980.1 - 0.00016 21.2 0.1 0.00049 19.6 0.0 1.7 2 0 0 2 2 2 1 Putative Phosphatase UMPH-1 PF05822.12 EGG00980.1 - 0.002 17.7 0.0 0.0042 16.6 0.0 1.7 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) LNS2 PF08235.13 EGG00980.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Methyltransf_16 PF10294.9 EGG00981.1 - 1.8e-08 34.3 0.0 2.3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase AP1AR PF15745.5 EGG00982.1 - 3.3 7.3 13.4 0.35 10.5 3.9 2.1 1 1 0 2 2 2 0 AP-1 complex-associated regulatory protein MAP7 PF05672.11 EGG00982.1 - 5.4 6.7 19.0 16 5.2 19.0 1.7 1 1 0 1 1 1 0 MAP7 (E-MAP-115) family RAI1 PF08652.11 EGG00986.1 - 0.0097 16.1 5.7 2.1 8.6 0.1 3.4 2 1 1 3 3 3 2 RAI1 like PD-(D/E)XK nuclease Zn_clus PF00172.18 EGG00988.1 - 8.1e-08 32.3 9.4 1.3e-07 31.6 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 EGG00989.1 - 2.4e-55 187.7 0.0 2.7e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG00989.1 - 5.4e-53 179.4 0.2 6.9e-53 179.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG00989.1 - 2.4e-09 37.4 0.1 3.3e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG00989.1 - 0.00036 20.1 0.1 0.0079 15.7 0.1 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 EGG00989.1 - 0.038 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme COPR5 PF15340.6 EGG00990.1 - 0.015 15.9 0.1 0.025 15.3 0.1 1.3 1 0 0 1 1 1 0 Cooperator of PRMT5 family DUF2321 PF10083.9 EGG00991.1 - 0.034 13.8 0.1 0.044 13.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) AFT PF08731.11 EGG00992.1 - 0.11 12.9 0.0 0.11 12.9 0.0 3.3 2 1 0 2 2 2 0 Transcription factor AFT DUF4954 PF16314.5 EGG00993.1 - 0.032 12.4 0.2 0.063 11.4 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) zf-CCHC PF00098.23 EGG00994.1 - 0.04 14.0 3.8 0.061 13.4 3.8 1.3 1 0 0 1 1 1 0 Zinc knuckle Sgf11_N PF18519.1 EGG00996.1 - 0.0057 16.2 0.1 0.015 14.9 0.1 1.7 1 0 0 1 1 1 1 SAGA-associated factor 11 N-terminal domain CLP_protease PF00574.23 EGG00996.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Clp protease HisKA_2 PF07568.12 EGG00997.1 - 0.034 14.2 0.1 0.087 12.9 0.1 1.7 1 1 0 1 1 1 0 Histidine kinase Gly_transf_sug PF04488.15 EGG01008.1 - 2.2e-13 50.7 0.0 7.7e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif CxC1 PF18802.1 EGG01012.1 - 0.07 13.3 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases DUF4159 PF13709.6 EGG01014.1 - 0.032 13.6 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Arginase PF00491.21 EGG01015.1 - 8.3e-75 251.9 0.0 9.7e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family PASTA PF03793.19 EGG01017.1 - 0.0048 16.7 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 PASTA domain Big_7 PF17957.1 EGG01017.1 - 0.046 14.5 0.1 0.081 13.7 0.1 1.6 1 1 0 1 1 1 0 Bacterial Ig domain CxC5 PF18718.1 EGG01018.1 - 7.3e-25 87.3 2.5 1.5e-24 86.3 2.5 1.5 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG01018.1 - 1e-19 70.6 0.8 1e-19 70.6 0.8 2.5 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases KaiA PF07688.12 EGG01019.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 KaiA C-terminal domain NRIP1_repr_3 PF15689.5 EGG01024.1 - 0.032 14.5 0.5 0.072 13.4 0.5 1.6 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 3 MFS_1 PF07690.16 EGG01025.1 - 1.5e-22 80.1 31.6 4.1e-22 78.6 31.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_U4 PF03419.13 EGG01025.1 - 0.014 14.8 0.4 0.014 14.8 0.4 2.4 2 1 0 2 2 2 0 Sporulation factor SpoIIGA UbiA PF01040.18 EGG01026.1 - 3.3e-05 23.3 0.1 3.4e-05 23.3 0.1 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family FixQ PF05545.11 EGG01026.1 - 1.1 9.3 4.8 1.5 8.9 4.8 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Cpn10 PF00166.21 EGG01028.1 - 3.3e-29 100.8 0.0 3.7e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Vault_2 PF17794.1 EGG01028.1 - 0.073 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Major Vault Protein repeat domain Trehalose_PPase PF02358.16 EGG01029.1 - 5.4e-20 71.5 0.3 8.6e-20 70.9 0.3 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EGG01029.1 - 5.6e-12 46.0 0.1 1.3e-08 35.0 0.2 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGG01029.1 - 9.5e-05 22.0 0.2 0.00023 20.8 0.2 1.6 1 1 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.16 EGG01030.1 - 8.8e-20 70.8 0.0 9.7e-11 41.2 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.12 EGG01030.1 - 9.2e-12 45.2 0.0 2.3e-09 37.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGG01030.1 - 4.4e-09 36.2 0.0 7.3e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase DUF2608 PF11019.8 EGG01030.1 - 0.022 14.3 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) M PF02370.16 EGG01033.1 - 5.8 7.8 6.3 6.8 7.6 0.6 3.3 3 0 0 3 3 3 0 M protein repeat Pentaxin PF00354.17 EGG01036.1 - 0.018 14.8 0.1 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 Pentaxin family RTC4 PF14474.6 EGG01037.1 - 2.2e-22 79.5 0.0 3.8e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain zf-CCHC PF00098.23 EGG01037.1 - 0.12 12.5 1.6 0.21 11.7 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGG01037.1 - 0.18 11.6 7.5 0.085 12.6 3.2 2.2 2 0 0 2 2 2 0 C2H2 zinc-finger Sacchrp_dh_C PF16653.5 EGG01038.1 - 4.9e-69 233.4 0.0 7.4e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 EGG01038.1 - 5.5e-65 218.3 0.0 1.1e-64 217.3 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Sacchrp_dh_NADP PF03435.18 EGG01038.1 - 8.6e-24 84.3 0.9 1.5e-23 83.5 0.2 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Spermine_synt_N PF17284.2 EGG01038.1 - 9.2e-21 73.5 0.0 1.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Shikimate_DH PF01488.20 EGG01038.1 - 1.8e-07 31.3 0.4 1.6e-06 28.2 0.2 2.6 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.6 EGG01038.1 - 0.0003 21.4 0.0 0.017 15.8 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.6 EGG01038.1 - 0.0023 17.9 0.1 0.004 17.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_12 PF08242.12 EGG01038.1 - 0.0026 18.5 0.0 0.5 11.1 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.19 EGG01038.1 - 0.0076 15.3 0.0 0.017 14.1 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGG01038.1 - 0.076 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HMG_box PF00505.19 EGG01039.1 - 3.5e-14 53.0 0.6 7e-14 52.0 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGG01039.1 - 0.00033 21.2 0.3 0.001 19.6 0.3 1.8 1 1 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 EGG01039.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Sugar_tr PF00083.24 EGG01040.1 - 1.8e-105 353.4 13.8 2.1e-105 353.2 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG01040.1 - 8.1e-28 97.3 27.3 1.2e-27 96.8 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Podovirus_Gp16 PF05894.12 EGG01041.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.5 2 0 0 2 2 2 0 Podovirus DNA encapsidation protein (Gp16) Podovirus_Gp16 PF05894.12 EGG01042.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.5 2 0 0 2 2 2 0 Podovirus DNA encapsidation protein (Gp16) YABBY PF04690.13 EGG01043.1 - 0.065 13.8 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 YABBY protein Ribosomal_L36 PF00444.18 EGG01045.1 - 2.3e-18 66.1 9.6 3.2e-18 65.6 9.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 SRP19 PF01922.17 EGG01046.1 - 0.012 16.5 0.4 0.52 11.3 0.1 2.3 2 0 0 2 2 2 0 SRP19 protein FlgD_ig PF13860.6 EGG01046.1 - 0.028 14.3 0.2 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain Barwin PF00967.17 EGG01047.1 - 0.0025 17.7 0.2 0.0036 17.1 0.2 1.2 1 0 0 1 1 1 1 Barwin family GTP_EFTU PF00009.27 EGG01048.1 - 1.5e-56 191.0 0.2 2.2e-56 190.5 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGG01048.1 - 1.8e-25 89.4 0.0 3.8e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGG01048.1 - 1.7e-14 53.9 2.6 3.6e-14 52.9 2.6 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGG01048.1 - 1.8e-05 24.8 0.1 3.9e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG01048.1 - 0.037 13.9 0.1 0.16 11.8 0.0 2.0 1 1 1 2 2 2 0 RsgA GTPase cobW PF02492.19 EGG01048.1 - 0.063 12.9 0.3 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EGG01048.1 - 0.11 12.3 0.1 8.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TPR_1 PF00515.28 EGG01049.1 - 9.4e-31 104.4 9.8 3.2e-06 26.7 0.0 8.7 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGG01049.1 - 1.6e-25 87.1 10.8 0.0016 18.4 0.1 10.2 10 1 1 11 11 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 EGG01049.1 - 1.2e-20 71.9 18.7 0.00023 21.1 0.0 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGG01049.1 - 5e-19 67.7 4.6 1.8e-05 24.4 0.0 7.2 7 0 0 7 7 7 3 TPR repeat TPR_12 PF13424.6 EGG01049.1 - 1e-14 54.6 12.5 0.0025 18.1 0.0 7.3 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGG01049.1 - 4.4e-12 45.5 1.7 0.024 15.0 0.0 8.1 8 2 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG01049.1 - 3.6e-11 42.9 6.4 0.076 13.9 0.0 8.3 4 3 6 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG01049.1 - 1.7e-10 41.3 10.1 0.056 14.1 0.0 6.8 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG01049.1 - 5.2e-10 39.7 1.0 0.23 12.0 0.1 6.1 3 1 4 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG01049.1 - 1.1e-08 35.1 8.3 0.51 10.6 0.1 5.4 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGG01049.1 - 8e-06 25.9 1.6 0.0077 16.4 0.1 4.8 4 2 1 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG01049.1 - 1.6e-05 24.6 4.2 1.9 8.7 0.1 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat NARP1 PF12569.8 EGG01049.1 - 5.6e-05 22.3 28.4 0.039 12.9 0.0 5.0 2 2 3 5 5 5 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 EGG01049.1 - 0.00027 20.2 5.5 2.6 7.2 0.0 5.3 3 2 1 5 5 5 1 Tetratricopeptide repeat HemX PF04375.14 EGG01049.1 - 0.0044 16.4 0.7 0.0094 15.3 0.7 1.5 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase SHNi-TPR PF10516.9 EGG01049.1 - 0.049 13.1 2.0 22 4.6 0.1 4.2 4 0 0 4 4 4 0 SHNi-TPR MIT PF04212.18 EGG01049.1 - 0.08 13.0 15.9 0.6 10.2 0.9 5.2 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF4192 PF13830.6 EGG01049.1 - 0.1 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) FancD2 PF14631.6 EGG01049.1 - 0.15 9.4 7.4 0.22 8.9 7.4 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease ABC2_membrane_3 PF12698.7 EGG01049.1 - 0.18 10.9 0.6 0.28 10.2 0.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein NRBF2_MIT PF17169.4 EGG01049.1 - 0.22 11.7 6.0 1.9 8.8 0.2 3.7 3 1 0 3 3 2 0 MIT domain of nuclear receptor-binding factor 2 TPR_10 PF13374.6 EGG01049.1 - 0.26 11.2 10.2 36 4.4 0.1 6.3 8 0 0 8 8 8 0 Tetratricopeptide repeat CLN3 PF02487.17 EGG01049.1 - 0.43 9.6 2.3 0.72 8.8 2.3 1.3 1 0 0 1 1 1 0 CLN3 protein TPR_6 PF13174.6 EGG01049.1 - 0.61 10.9 13.7 97 3.9 0.0 7.6 10 0 0 10 10 7 0 Tetratricopeptide repeat O-antigen_lig PF13425.6 EGG01049.1 - 0.73 8.6 6.0 1.1 7.9 6.0 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF908 PF06012.12 EGG01049.1 - 1.9 7.8 14.1 5.9 6.2 12.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Presenilin PF01080.17 EGG01049.1 - 2.3 6.9 8.7 3.6 6.3 8.7 1.2 1 0 0 1 1 1 0 Presenilin Rotamase PF00639.21 EGG01050.1 - 2.5e-19 70.0 0.2 3.6e-19 69.5 0.2 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EGG01050.1 - 2.5e-19 69.9 0.0 3.9e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EGG01050.1 - 0.00011 22.1 2.7 0.00013 22.0 0.8 1.9 2 0 0 2 2 2 1 WW domain Mcm10 PF09332.11 EGG01050.1 - 0.029 13.8 0.0 0.029 13.8 0.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor HNH_2 PF13391.6 EGG01050.1 - 0.046 13.8 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 HNH endonuclease Rotamase_2 PF13145.6 EGG01050.1 - 0.11 13.3 0.0 0.14 13.0 0.0 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain MARVEL PF01284.23 EGG01052.1 - 1.4e-06 28.4 5.3 3.2e-06 27.2 5.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain Lig_chan PF00060.26 EGG01052.1 - 0.0079 16.0 0.3 0.012 15.5 0.3 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel DUF3899 PF13038.6 EGG01052.1 - 0.88 10.1 0.0 0.88 10.1 0.0 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF3899) DUF2012 PF09430.10 EGG01053.1 - 1.8e-18 66.8 0.0 3.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) FAF PF11250.8 EGG01053.1 - 0.059 13.6 1.3 0.078 13.2 0.1 1.9 2 0 0 2 2 2 0 Fantastic Four meristem regulator CN_hydrolase PF00795.22 EGG01054.1 - 4.1e-19 68.9 0.0 5e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Abhydrolase_6 PF12697.7 EGG01055.1 - 1.9e-08 35.2 5.7 2.6e-08 34.7 5.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG01055.1 - 5.9e-06 26.1 0.0 9.2e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG01055.1 - 0.00019 20.8 0.0 0.00026 20.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EGG01055.1 - 0.042 13.5 0.0 0.06 12.9 0.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EGG01055.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Pro_isomerase PF00160.21 EGG01056.1 - 8e-50 169.2 0.0 1.1e-48 165.5 0.0 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 EGG01056.1 - 2.5e-05 24.4 1.2 0.00051 20.2 0.0 2.9 2 1 1 3 3 3 1 U-box domain zf-NOSIP PF15906.5 EGG01056.1 - 0.0051 16.9 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein TrbI_Ftype PF09677.10 EGG01056.1 - 0.021 15.1 0.1 0.038 14.3 0.1 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Rtf2 PF04641.12 EGG01056.1 - 0.073 12.4 0.0 0.073 12.4 0.0 2.2 3 0 0 3 3 3 0 Rtf2 RING-finger Snf7 PF03357.21 EGG01057.1 - 2e-32 112.2 21.2 2.6e-32 111.8 21.2 1.0 1 0 0 1 1 1 1 Snf7 DUF3641 PF12345.8 EGG01057.1 - 0.32 11.0 1.7 2.2 8.3 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) AAA_17 PF13207.6 EGG01057.1 - 0.73 10.3 5.4 0.22 12.0 1.0 2.0 2 0 0 2 2 2 0 AAA domain Ribul_P_3_epim PF00834.19 EGG01059.1 - 3.2e-61 206.2 0.1 3.9e-61 205.9 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family JmjN PF02375.17 EGG01059.1 - 0.073 13.1 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 jmjN domain PG_binding_3 PF09374.10 EGG01059.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Ribosomal_S7 PF00177.21 EGG01060.1 - 5.3e-21 74.8 0.0 7.6e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF3446 PF11928.8 EGG01060.1 - 0.11 12.9 0.8 0.18 12.1 0.8 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain MIS13 PF08202.11 EGG01063.1 - 0.019 14.3 0.1 0.035 13.4 0.1 1.4 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Cellulase PF00150.18 EGG01066.1 - 5.8e-40 137.5 0.0 7.6e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 EGG01067.1 - 9.8e-42 143.3 0.0 1.1e-41 143.1 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ENTH PF01417.20 EGG01069.1 - 9.4e-47 158.2 0.1 1.5e-46 157.5 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EGG01069.1 - 0.00015 20.8 1.0 0.00023 20.2 0.0 1.8 2 0 0 2 2 2 1 ANTH domain UIM PF02809.20 EGG01069.1 - 0.0086 15.9 4.7 0.39 10.7 0.2 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF1635 PF07795.11 EGG01069.1 - 0.63 9.9 0.0 0.63 9.9 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1635) CYSTM PF12734.7 EGG01069.1 - 6.2 7.2 11.7 1.2e+02 3.1 9.3 3.1 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance YbjQ_1 PF01906.17 EGG01070.1 - 0.0029 18.2 0.1 0.34 11.6 0.0 2.2 2 0 0 2 2 2 2 Putative heavy-metal-binding Tropomyosin PF00261.20 EGG01071.1 - 0.0021 17.5 1.6 0.0033 16.8 1.6 1.2 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.7 EGG01071.1 - 0.024 14.8 0.7 0.046 13.9 0.7 1.4 1 0 0 1 1 1 0 Tropomyosin like TMCO5 PF14992.6 EGG01071.1 - 0.12 11.9 0.5 0.19 11.3 0.5 1.2 1 0 0 1 1 1 0 TMCO5 family BAR_2 PF10455.9 EGG01073.1 - 2.9e-46 157.9 3.0 7.4e-46 156.6 3.0 1.6 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EGG01073.1 - 4.2e-15 56.0 4.8 1.3e-10 41.4 1.6 2.1 2 0 0 2 2 2 2 BAR domain CHAD PF05235.14 EGG01073.1 - 0.0014 18.7 7.9 0.0024 17.9 7.9 1.4 1 1 0 1 1 1 1 CHAD domain Phasin PF05597.11 EGG01073.1 - 0.032 14.2 2.8 0.042 13.9 0.1 2.5 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Vps5 PF09325.10 EGG01073.1 - 0.035 13.6 3.9 0.34 10.4 0.2 2.5 2 0 0 2 2 2 0 Vps5 C terminal like TBCC_N PF16752.5 EGG01073.1 - 0.056 13.9 3.9 0.085 13.3 0.6 2.5 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Uds1 PF15456.6 EGG01073.1 - 0.15 12.3 8.1 0.53 10.4 0.1 3.0 2 2 1 3 3 3 0 Up-regulated During Septation TACC_C PF05010.14 EGG01073.1 - 0.58 9.9 6.2 3.5 7.4 0.0 3.3 2 1 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Baculo_PEP_C PF04513.12 EGG01073.1 - 4.1 7.5 9.1 0.35 10.9 0.2 3.0 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FA_hydroxylase PF04116.13 EGG01074.1 - 3.9e-24 85.5 16.5 3.9e-24 85.5 16.5 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily ThiF PF00899.21 EGG01074.1 - 0.079 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 ThiF family HPS6 PF15702.5 EGG01074.1 - 0.18 9.8 0.0 0.25 9.3 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein GATase PF00117.28 EGG01076.1 - 7.4e-06 25.9 0.1 4.6e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I NAD_kinase PF01513.21 EGG01077.1 - 9e-57 192.5 0.0 1.3e-56 192.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EGG01077.1 - 9.2e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ribosomal_S19 PF00203.21 EGG01078.1 - 6.7e-27 93.2 0.0 8.4e-27 92.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 PC_rep PF01851.22 EGG01079.1 - 6.1e-44 146.3 22.2 1.4e-10 41.0 0.1 8.1 7 0 0 7 7 7 7 Proteasome/cyclosome repeat RPN2_C PF18004.1 EGG01079.1 - 4.5e-41 140.4 3.8 7e-40 136.6 3.1 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 EGG01079.1 - 1.2e-21 76.9 3.5 1.3e-14 54.4 0.0 5.1 3 1 3 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 EGG01079.1 - 1e-05 25.9 0.5 0.0082 16.6 0.0 4.5 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 EGG01079.1 - 0.00016 21.7 0.6 4.2 7.9 0.1 4.5 3 0 0 3 3 3 1 HEAT repeat HEAT_PBS PF03130.16 EGG01079.1 - 0.012 16.2 0.9 4.8 8.1 0.1 4.1 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat ERAP1_C PF11838.8 EGG01079.1 - 0.085 12.4 2.0 2.8 7.4 0.0 3.5 3 2 1 4 4 4 0 ERAP1-like C-terminal domain Arm PF00514.23 EGG01079.1 - 0.096 12.8 1.0 19 5.5 0.0 4.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGG01079.1 - 0.097 12.7 0.0 2.8 8.0 0.0 2.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 PMT PF02366.18 EGG01080.1 - 3.6e-83 278.9 18.5 3.6e-83 278.9 18.5 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGG01080.1 - 2.7e-60 203.4 12.1 8.4e-60 201.8 10.3 2.5 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGG01080.1 - 4.1e-33 114.8 0.6 4.1e-33 114.8 0.6 2.1 2 1 1 3 3 3 1 MIR domain EVI2A PF05399.11 EGG01080.1 - 0.014 15.0 1.8 0.031 13.9 1.8 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Mre11_DNA_bind PF04152.14 EGG01081.1 - 1e-49 169.1 0.2 1.3e-49 168.7 0.2 1.2 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EGG01081.1 - 1.5e-13 51.7 0.6 2.9e-13 50.8 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG01081.1 - 0.00044 20.5 0.0 0.012 15.8 0.0 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FXMRP1_C_core PF12235.8 EGG01082.1 - 2.5 8.7 29.2 0.1 13.2 11.3 3.0 3 1 0 3 3 3 0 Fragile X-related 1 protein core C terminal COPI_C PF06957.11 EGG01082.1 - 3.6 6.2 9.8 4.9 5.8 9.8 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus FA_desaturase PF00487.24 EGG01083.1 - 0.00052 19.9 1.2 0.00075 19.4 1.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Mre11_DNA_bind PF04152.14 EGG01084.1 - 1.3e-05 25.6 0.1 1.3e-05 25.6 0.1 3.3 3 2 1 4 4 4 1 Mre11 DNA-binding presumed domain FmdE PF02663.14 EGG01084.1 - 0.034 14.2 0.9 0.1 12.6 0.9 1.8 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Sugar_tr PF00083.24 EGG01085.1 - 1.1e-106 357.5 16.2 1.2e-106 357.3 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG01085.1 - 5.6e-30 104.5 24.8 5.6e-30 104.5 24.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 EGG01091.1 - 0.58 10.3 7.0 3.5 7.8 2.0 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Adeno_knob PF00541.17 EGG01092.1 - 0.041 13.6 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 Adenoviral fibre protein (knob domain) Sad1_UNC PF07738.13 EGG01096.1 - 1.9e-27 95.8 0.0 2.7e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF5000 PF16391.5 EGG01096.1 - 0.12 12.5 0.0 3.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function Peptidase_M18 PF02127.15 EGG01100.1 - 9.8e-12 44.4 1.0 3.5e-06 26.1 0.1 3.6 1 1 3 4 4 4 3 Aminopeptidase I zinc metalloprotease (M18) Suc_Fer-like PF06999.12 EGG01101.1 - 2.2e-47 161.5 0.0 3.4e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like HSCB_C PF07743.13 EGG01103.1 - 2.1e-15 56.9 6.0 2.1e-15 56.9 6.0 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain Zn_ribbon_SprT PF17283.2 EGG01103.1 - 0.0037 17.1 0.6 0.0083 16.0 0.6 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DnaJ PF00226.31 EGG01103.1 - 0.0039 17.3 0.1 0.47 10.6 0.0 3.2 3 1 0 3 3 3 1 DnaJ domain zf-ribbon_3 PF13248.6 EGG01103.1 - 0.088 12.2 0.5 0.088 12.2 0.5 1.9 3 0 0 3 3 3 0 zinc-ribbon domain T6PP_N PF18572.1 EGG01103.1 - 0.14 12.0 2.2 7.9 6.4 1.3 2.3 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain HypA PF01155.19 EGG01103.1 - 0.14 12.2 0.3 0.73 9.9 0.0 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 EGG01103.1 - 0.19 12.0 1.7 14 6.0 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon YCII PF03795.14 EGG01104.1 - 1.1e-05 25.7 0.0 1.5e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Cpn60_TCP1 PF00118.24 EGG01105.1 - 4.2e-87 292.8 9.1 7.7e-87 292.0 9.1 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1542 PF07564.11 EGG01105.1 - 4.4 7.5 6.5 1.6 8.9 1.4 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) Presenilin PF01080.17 EGG01108.1 - 1.6 7.4 5.2 2.1 7.0 5.2 1.1 1 0 0 1 1 1 0 Presenilin Dicty_REP PF05086.12 EGG01108.1 - 3.6 5.5 10.7 4.2 5.2 10.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cu-oxidase_3 PF07732.15 EGG01109.1 - 1.4e-42 144.5 4.7 4.7e-42 142.8 0.5 2.8 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG01109.1 - 1.1e-34 119.2 3.1 1.3e-30 105.9 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EGG01109.1 - 4.3e-24 85.4 0.1 9.7e-23 81.0 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase DHHC PF01529.20 EGG01113.1 - 3.2e-31 108.2 14.3 3.8e-31 108.0 14.3 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF899 PF05988.12 EGG01113.1 - 7.8 6.0 5.5 11 5.5 5.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Big_7 PF17957.1 EGG01114.1 - 0.0045 17.7 0.2 0.0072 17.1 0.2 1.4 1 0 0 1 1 1 1 Bacterial Ig domain Alpha_kinase PF02816.18 EGG01117.1 - 3.2e-12 46.9 0.9 3.6e-12 46.8 0.9 1.0 1 0 0 1 1 1 1 Alpha-kinase family Big_7 PF17957.1 EGG01118.1 - 0.0084 16.9 3.3 0.022 15.5 3.1 1.9 1 1 0 1 1 1 1 Bacterial Ig domain RVP_2 PF08284.11 EGG01119.1 - 0.12 12.2 0.8 0.12 12.1 0.8 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease pP_pnuc_2 PF18166.1 EGG01121.1 - 0.022 14.8 0.3 0.027 14.6 0.3 1.1 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease SmpB PF01668.18 EGG01121.1 - 0.034 14.0 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 SmpB protein DS PF01916.17 EGG01122.1 - 6.5e-06 25.6 0.0 6.7e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Fusion_F0 PF13044.6 EGG01123.1 - 0.079 11.6 0.3 0.081 11.6 0.3 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus zf-BED PF02892.15 EGG01124.1 - 0.00013 21.9 1.3 0.001 19.0 1.3 2.1 1 1 0 1 1 1 1 BED zinc finger Beta_elim_lyase PF01212.21 EGG01125.1 - 6.6e-69 232.4 0.0 8.1e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EGG01125.1 - 0.0003 20.1 0.0 0.00046 19.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGG01125.1 - 0.039 12.9 0.1 0.064 12.2 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DUF851 PF05867.11 EGG01125.1 - 0.059 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF851) CxC5 PF18718.1 EGG01127.1 - 0.036 14.2 0.3 0.3 11.2 0.2 2.1 1 1 1 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases PDEase_I PF00233.19 EGG01128.1 - 1.9e-47 162.0 0.0 2.2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase tRNA-synt_1d PF00750.19 EGG01130.1 - 2.5e-106 355.5 2.5 3.2e-106 355.2 2.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EGG01130.1 - 4e-18 65.7 0.0 7.1e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1e PF01406.19 EGG01130.1 - 0.024 14.0 0.0 0.051 12.9 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain ATG16 PF08614.11 EGG01131.1 - 3.4e-40 138.4 26.2 4.3e-40 138.1 26.2 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 EGG01131.1 - 0.0012 18.7 2.8 0.0012 18.7 2.8 2.9 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding Peptidase_S8_N PF16361.5 EGG01131.1 - 0.0053 17.3 0.8 0.013 15.9 0.8 1.6 1 0 0 1 1 1 1 N-terminal of Subtilase family DUF812 PF05667.11 EGG01131.1 - 0.012 14.6 9.8 0.015 14.2 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fez1 PF06818.15 EGG01131.1 - 0.39 11.2 17.0 0.14 12.6 4.5 2.2 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 EGG01131.1 - 1.2 9.1 4.3 1.9 8.6 3.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EGG01131.1 - 1.4 8.2 16.6 3.1 7.1 16.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 EGG01131.1 - 1.8 9.1 22.8 0.11 13.0 3.7 4.1 2 1 1 3 3 3 0 Cell division protein ZapB zf-C4H2 PF10146.9 EGG01131.1 - 2.2 8.5 9.0 0.13 12.6 4.2 1.4 2 0 0 2 2 2 0 Zinc finger-containing protein CCDC85 PF10226.9 EGG01131.1 - 2.3 7.8 13.4 0.46 10.1 7.7 2.3 2 1 1 3 3 3 0 CCDC85 family DUF16 PF01519.16 EGG01131.1 - 2.4 8.7 8.2 0.35 11.4 3.8 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4201 PF13870.6 EGG01131.1 - 2.8 7.6 19.0 1.8 8.3 12.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) V_ATPase_I PF01496.19 EGG01131.1 - 3.7 5.4 5.9 5.1 4.9 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MPS2 PF17060.5 EGG01131.1 - 3.9 6.7 8.2 11 5.2 8.3 1.7 1 1 0 1 1 1 0 Monopolar spindle protein 2 YabA PF06156.13 EGG01131.1 - 4 8.1 16.9 0.53 11.0 3.5 2.8 2 1 2 4 4 4 0 Initiation control protein YabA YlqD PF11068.8 EGG01131.1 - 7.4 7.0 15.2 1.1 9.7 9.3 2.3 2 1 0 2 2 2 0 YlqD protein COG2 PF06148.11 EGG01131.1 - 8.4 6.5 13.0 1.2 9.3 7.2 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Pex24p PF06398.11 EGG01132.1 - 9.7e-39 133.4 16.6 4.1e-38 131.3 16.6 1.8 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin EI24 PF07264.11 EGG01133.1 - 0.0013 19.0 7.7 0.0038 17.5 7.7 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Phage_int_SAM_3 PF14659.6 EGG01133.1 - 0.043 14.1 0.5 1.5 9.1 0.0 2.9 3 1 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain PI-PLC-C1 PF16670.5 EGG01134.1 - 0.013 14.6 0.8 2.7 7.0 0.0 2.6 1 1 2 3 3 3 0 Phosphoinositide phospholipase C, Ca2+-dependent DUF3713 PF12506.8 EGG01134.1 - 0.52 10.6 0.0 0.52 10.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3713) Phos_pyr_kin PF08543.12 EGG01136.1 - 8.8e-10 38.4 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EGG01136.1 - 3.7e-07 29.7 0.0 9.5e-06 25.1 0.0 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF3605 PF12239.8 EGG01137.1 - 3.1e-14 53.6 0.3 3.6e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) GCM PF03615.15 EGG01138.1 - 0.00041 20.2 1.6 0.00089 19.2 1.6 1.5 1 0 0 1 1 1 1 GCM motif protein FBPase_3 PF01950.16 EGG01138.1 - 0.088 12.0 0.8 0.13 11.4 0.8 1.2 1 0 0 1 1 1 0 Fructose-1,6-bisphosphatase CBFD_NFYB_HMF PF00808.23 EGG01139.1 - 2e-08 34.4 0.1 9.7e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cwf_Cwc_15 PF04889.12 EGG01139.1 - 0.064 13.0 14.6 0.081 12.7 14.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TAFII28 PF04719.14 EGG01139.1 - 0.087 12.9 0.0 0.087 12.9 0.0 2.2 2 1 0 2 2 2 0 hTAFII28-like protein conserved region BSP_II PF05432.11 EGG01139.1 - 1.5 8.4 19.7 1.9 8.1 19.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TFIIB PF00382.19 EGG01140.1 - 1.3e-38 130.8 0.0 1.5e-19 69.8 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EGG01140.1 - 2e-25 89.1 1.6 2e-25 89.1 1.6 3.7 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EGG01140.1 - 6.6e-11 41.5 2.5 1.9e-10 40.1 2.5 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EGG01140.1 - 0.00034 20.4 0.1 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-RRN7 PF11781.8 EGG01140.1 - 0.0062 16.2 0.7 0.013 15.2 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 AIM3 PF17096.5 EGG01140.1 - 0.0083 17.0 6.8 0.0083 17.0 6.8 3.2 3 0 0 3 3 3 1 Altered inheritance of mitochondria protein 3 Lar_restr_allev PF14354.6 EGG01140.1 - 0.011 16.1 0.3 0.04 14.3 0.3 2.0 1 0 0 1 1 1 0 Restriction alleviation protein Lar Ribosomal_S27e PF01667.17 EGG01140.1 - 0.076 12.7 1.3 0.17 11.6 1.3 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 DUF4834 PF16118.5 EGG01140.1 - 0.9 10.5 11.9 2.3 9.2 3.5 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF525 PF04379.14 EGG01142.1 - 0.084 13.1 0.0 2.9 8.2 0.0 2.3 2 0 0 2 2 2 0 ApaG domain Pox_Ag35 PF03286.14 EGG01142.1 - 6 6.6 14.3 0.89 9.3 10.3 1.6 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Nucleo_P87 PF07267.11 EGG01142.1 - 9.9 4.9 7.6 13 4.5 7.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Inositol_P PF00459.25 EGG01147.1 - 1.8e-70 237.6 0.0 2.1e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Cu2_monooxygen PF01082.20 EGG01148.1 - 0.16 12.2 0.4 2.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DPBB_1 PF03330.18 EGG01149.1 - 1.5e-08 34.8 0.0 1.4e-07 31.7 0.0 2.7 3 0 0 3 3 3 1 Lytic transglycolase DUF4175 PF13779.6 EGG01149.1 - 0.053 11.4 1.7 0.24 9.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Apt1 PF10351.9 EGG01149.1 - 4.9 5.9 8.4 0.075 11.9 1.6 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF3306 PF11748.8 EGG01150.1 - 0.029 15.2 0.1 0.029 15.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Symplekin_C PF12295.8 EGG01151.1 - 1.9e-61 207.4 2.5 4.4e-61 206.2 0.9 2.5 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 EGG01151.1 - 1.3e-34 119.9 1.4 1.3e-34 119.9 1.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) DCB PF16213.5 EGG01151.1 - 0.21 11.3 4.6 8.3 6.0 0.5 3.6 4 0 0 4 4 4 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF5578 PF17741.1 EGG01151.1 - 0.38 10.1 2.8 32 3.8 0.3 3.8 4 0 0 4 4 4 0 Family of unknown function (DUF5578) ABC2_membrane PF01061.24 EGG01152.1 - 2.5e-60 203.5 61.6 3.2e-31 108.4 23.1 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGG01152.1 - 6.5e-30 104.4 0.0 2.4e-15 57.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGG01152.1 - 2.4e-29 101.1 7.2 4.9e-22 77.6 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EGG01152.1 - 3.4e-08 34.0 0.1 1e-07 32.5 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EGG01152.1 - 5.2e-08 32.4 3.0 5.2e-08 32.4 3.0 3.2 2 1 0 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGG01152.1 - 0.00015 21.7 0.0 0.58 9.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGG01152.1 - 0.00078 19.4 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EGG01152.1 - 0.0012 18.9 0.4 0.79 9.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EGG01152.1 - 0.0019 17.9 0.2 0.023 14.4 0.3 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EGG01152.1 - 0.012 15.2 0.2 0.073 12.6 0.1 2.3 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.19 EGG01152.1 - 0.012 15.1 0.0 1.5 8.2 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGG01152.1 - 0.065 13.6 0.0 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 EGG01152.1 - 0.066 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGG01152.1 - 3.3 8.2 4.9 1.1 9.8 0.2 2.3 3 0 0 3 3 3 0 AAA domain DUF948 PF06103.11 EGG01156.1 - 9.7e-05 22.6 0.7 0.00033 20.9 0.7 1.9 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EGG01156.1 - 0.00087 19.3 1.7 0.0016 18.5 0.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EGG01156.1 - 0.0029 17.8 0.8 0.0071 16.5 0.3 1.8 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family MCPsignal PF00015.21 EGG01156.1 - 0.0042 16.9 0.5 0.01 15.7 0.5 1.6 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.12 EGG01156.1 - 0.0086 16.1 1.2 0.069 13.2 0.2 2.3 2 1 0 2 2 2 1 Laminin Domain II NPV_P10 PF05531.12 EGG01156.1 - 0.01 16.3 2.0 0.021 15.3 1.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EGG01156.1 - 0.016 15.3 2.7 0.043 13.9 2.0 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 EGG01156.1 - 0.017 15.4 1.0 0.14 12.5 0.4 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4795 PF16043.5 EGG01156.1 - 0.026 14.2 0.2 0.047 13.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4559 PF15112.6 EGG01156.1 - 0.035 13.8 0.6 0.067 12.9 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) FlaC_arch PF05377.11 EGG01156.1 - 0.051 14.0 0.7 0.16 12.4 0.7 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PMC2NT PF08066.12 EGG01156.1 - 0.074 13.8 1.0 0.29 11.9 1.0 2.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Spidroin_N PF16763.5 EGG01156.1 - 0.074 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term Sec34 PF04136.15 EGG01156.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Sec34-like family Hormone_1 PF00103.20 EGG01156.1 - 0.11 12.2 0.4 0.33 10.7 0.4 1.8 1 1 0 1 1 1 0 Somatotropin hormone family Complex1_49kDa PF00346.19 EGG01156.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit KxDL PF10241.9 EGG01156.1 - 0.16 12.3 0.1 0.37 11.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein YtxH PF12732.7 EGG01156.1 - 0.16 12.5 0.3 4.9 7.8 0.1 2.7 2 2 0 2 2 2 0 YtxH-like protein DUF5082 PF16888.5 EGG01156.1 - 0.17 12.2 0.2 0.53 10.6 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) COG2 PF06148.11 EGG01156.1 - 0.25 11.4 1.5 0.86 9.7 0.2 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HAD_2 PF13419.6 EGG01157.1 - 2.4e-21 76.6 0.0 7.5e-21 75.0 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG01157.1 - 1.8e-10 41.5 0.0 2.4e-09 37.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGG01157.1 - 0.02 15.0 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like HAD PF12710.7 EGG01157.1 - 0.054 13.9 0.0 0.073 13.5 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ALMT PF11744.8 EGG01161.1 - 9.4 4.9 14.4 13 4.5 14.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter MMS19_C PF12460.8 EGG01162.1 - 3.2e-116 388.9 0.0 1.7e-115 386.5 0.0 2.1 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 EGG01162.1 - 2.5e-67 227.2 0.0 4.4e-66 223.1 0.0 2.5 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 EGG01162.1 - 0.013 15.9 3.8 14 6.3 0.4 4.5 4 0 0 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.6 EGG01162.1 - 0.024 15.0 0.2 0.94 9.9 0.0 3.1 2 0 0 2 2 2 0 HEAT repeats ParcG PF10274.9 EGG01162.1 - 0.053 13.7 0.2 0.15 12.1 0.2 1.7 1 0 0 1 1 1 0 Parkin co-regulated protein ERAP1_C PF11838.8 EGG01162.1 - 0.16 11.5 0.0 3.7 7.0 0.0 2.8 3 0 0 3 3 3 0 ERAP1-like C-terminal domain Coiled PF05710.12 EGG01163.1 - 0.061 14.2 8.5 0.11 13.3 8.5 1.5 1 0 0 1 1 1 0 Coiled coil GPI-anchored PF10342.9 EGG01164.1 - 1.5e-05 25.6 0.1 2.5e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GTP_EFTU PF00009.27 EGG01165.1 - 2.5e-48 164.2 0.0 4e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EGG01165.1 - 2.9e-38 130.3 0.6 5.5e-38 129.4 0.6 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EGG01165.1 - 9e-16 57.7 0.0 1.8e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGG01165.1 - 6.2e-05 23.3 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGG01165.1 - 0.00012 22.1 0.0 0.00029 20.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EGG01165.1 - 0.0018 18.1 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EGG01165.1 - 0.002 17.9 0.0 0.0072 16.1 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation EFG_II PF14492.6 EGG01165.1 - 0.0023 18.0 0.1 0.013 15.5 0.1 2.3 2 1 0 2 2 2 1 Elongation Factor G, domain II RF3_C PF16658.5 EGG01165.1 - 0.0023 17.8 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ras PF00071.22 EGG01165.1 - 0.0025 17.4 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1_Xtn PF16897.5 EGG01165.1 - 0.011 15.7 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 EGG01165.1 - 0.062 12.7 0.1 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGG01165.1 - 0.098 12.6 0.0 0.33 10.8 0.0 1.9 2 1 0 2 2 2 0 RsgA GTPase GCP_C_terminal PF04130.13 EGG01166.1 - 0.0008 19.0 11.9 0.0055 16.2 12.9 1.9 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal His_Phos_1 PF00300.22 EGG01166.1 - 0.034 13.8 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) KapB PF08810.10 EGG01166.1 - 0.31 11.2 4.0 0.92 9.7 4.0 1.9 1 0 0 1 1 1 0 Kinase associated protein B Pro_sub2 PF18513.1 EGG01166.1 - 0.65 10.2 6.6 0.69 10.1 0.3 3.4 2 2 2 4 4 4 0 Prodomain subtilisin 2 Pex19 PF04614.12 EGG01166.1 - 1.4 8.7 15.7 1.9 8.2 14.2 2.0 1 1 0 1 1 1 0 Pex19 protein family PCNA_N PF00705.18 EGG01168.1 - 4.1e-54 181.7 7.9 4.1e-53 178.4 6.6 2.2 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EGG01168.1 - 1e-46 158.2 0.3 3e-46 156.7 0.1 1.8 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 EGG01168.1 - 2.7e-08 33.2 2.6 3.2e-06 26.4 2.6 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EGG01168.1 - 1.4e-05 24.7 0.3 1.8e-05 24.3 0.3 1.2 1 0 0 1 1 1 1 Rad9 RE_HpaII PF09561.10 EGG01168.1 - 0.044 13.2 0.3 0.061 12.7 0.3 1.2 1 0 0 1 1 1 0 HpaII restriction endonuclease DUF2334 PF10096.9 EGG01169.1 - 0.023 14.4 0.2 0.025 14.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF188 PF02639.14 EGG01169.1 - 0.041 13.5 1.1 0.075 12.7 1.1 1.4 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 FidL_like PF15941.5 EGG01169.1 - 2.2 8.8 5.2 1.9 9.0 3.3 1.8 1 1 1 2 2 2 0 FidL-like putative membrane protein potato_inhibit PF00280.18 EGG01170.1 - 0.05 14.3 0.2 0.086 13.5 0.2 1.4 1 0 0 1 1 1 0 Potato inhibitor I family YppG PF14179.6 EGG01170.1 - 0.36 11.6 10.7 0.58 10.9 10.7 1.3 1 0 0 1 1 1 0 YppG-like protein TFIIA PF03153.13 EGG01173.1 - 0.012 15.6 29.3 0.015 15.4 29.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EGG01173.1 - 0.038 12.3 32.0 0.043 12.1 32.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 EGG01173.1 - 0.097 12.2 18.0 0.12 11.9 18.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3523 PF12037.8 EGG01173.1 - 0.11 11.9 34.0 0.21 10.9 34.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) GREB1 PF15782.5 EGG01173.1 - 0.57 7.2 14.5 0.62 7.1 14.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer V_ATPase_I PF01496.19 EGG01173.1 - 2.5 5.9 12.4 2.7 5.8 12.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 EGG01173.1 - 5.4 7.0 10.1 6.8 6.7 10.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MRI PF15325.6 EGG01173.1 - 6.3 7.9 11.3 1.2 10.2 0.1 3.1 2 1 1 3 3 3 0 Modulator of retrovirus infection Presenilin PF01080.17 EGG01173.1 - 8.1 5.1 14.4 10 4.8 14.4 1.2 1 0 0 1 1 1 0 Presenilin VPS28 PF03997.12 EGG01174.1 - 5.3e-56 189.3 0.0 6.1e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein START PF01852.19 EGG01175.1 - 9.2e-20 70.9 0.0 3.9e-09 36.2 0.0 3.7 3 1 0 3 3 3 3 START domain Ubiq_cyt_C_chap PF03981.12 EGG01176.1 - 8.4e-22 77.8 0.0 1.4e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone APG6 PF04111.12 EGG01177.1 - 1.9e-63 213.7 0.0 3.6e-63 212.8 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EGG01177.1 - 4.3e-27 95.3 21.1 5.9e-27 94.8 21.1 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region TraC PF07820.12 EGG01177.1 - 0.0042 17.4 2.6 0.0078 16.5 2.6 1.5 1 0 0 1 1 1 1 TraC-like protein DUF4530 PF15039.6 EGG01177.1 - 0.0084 16.2 3.2 0.015 15.4 3.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) Leu_zip PF15294.6 EGG01177.1 - 0.011 15.2 8.8 0.019 14.5 8.8 1.2 1 0 0 1 1 1 0 Leucine zipper IFT57 PF10498.9 EGG01177.1 - 0.013 14.5 8.2 0.018 14.0 8.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF724 PF05266.14 EGG01177.1 - 0.35 10.7 10.9 0.62 9.9 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF2095 PF09868.9 EGG01177.1 - 0.4 10.7 6.6 0.64 10.0 1.6 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) Med4 PF10018.9 EGG01177.1 - 0.7 9.5 8.1 0.35 10.5 6.0 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CENP-H PF05837.12 EGG01177.1 - 2.6 8.5 10.2 1 9.8 7.0 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) SRF-TF PF00319.18 EGG01178.1 - 9.3e-25 85.9 0.0 1.1e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) RF-1 PF00472.20 EGG01179.1 - 3.9e-15 55.8 4.4 1.4e-13 50.8 4.3 2.2 1 1 0 1 1 1 1 RF-1 domain ERG2_Sigma1R PF04622.12 EGG01181.1 - 9.6e-95 315.8 0.2 1.3e-94 315.4 0.2 1.1 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein PIP49_N PF14875.6 EGG01182.1 - 0.096 12.5 0.3 0.17 11.7 0.3 1.3 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 GPI-anchored PF10342.9 EGG01183.1 - 0.019 15.7 1.6 0.039 14.7 1.6 1.5 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKG6 PF08693.10 EGG01183.1 - 0.48 9.9 4.0 0.86 9.1 4.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4342 PF14242.6 EGG01183.1 - 1.9 8.6 3.3 3.4 7.7 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) DsbC_N PF10411.9 EGG01184.1 - 0.083 12.3 0.0 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 Disulfide bond isomerase protein N-terminus DUF3195 PF11424.8 EGG01191.1 - 0.1 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGG01191.1 - 0.15 11.0 0.4 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 NUC194 domain DUF2170 PF09938.9 EGG01191.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) DUF4354 PF14263.6 EGG01194.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) Nop14 PF04147.12 EGG01196.1 - 0.0019 16.6 10.1 0.0027 16.0 10.1 1.2 1 0 0 1 1 1 1 Nop14-like family DUF763 PF05559.11 EGG01200.1 - 0.024 13.8 1.0 0.028 13.6 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) CCDC-167 PF15188.6 EGG01200.1 - 0.2 12.0 7.3 2.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Tna_leader PF08053.11 EGG01203.1 - 0.2 11.6 0.4 0.43 10.6 0.4 1.5 1 0 0 1 1 1 0 Tryptophanase operon leader peptide p450 PF00067.22 EGG01204.1 - 9.9e-62 209.2 0.0 1.3e-61 208.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_41 PF14502.6 EGG01204.1 - 0.064 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DPPIV_N PF00930.21 EGG01205.1 - 6.9e-82 275.0 0.0 9.1e-82 274.6 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EGG01205.1 - 1.3e-45 155.5 0.9 2.3e-45 154.7 0.9 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGG01205.1 - 0.00041 21.0 0.1 0.00099 19.8 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EGG01205.1 - 0.028 14.0 0.4 0.058 13.0 0.4 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 EGG01205.1 - 0.043 12.5 0.0 0.089 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 EGG01205.1 - 0.081 12.6 0.4 0.24 11.0 0.1 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 EGG01205.1 - 0.099 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 EGG01205.1 - 0.14 11.4 0.1 0.37 10.0 0.1 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 ATP-synt_8 PF00895.20 EGG01205.1 - 0.4 11.2 2.7 1.5 9.4 2.7 1.9 1 0 0 1 1 1 0 ATP synthase protein 8 HIG_1_N PF04588.13 EGG01206.1 - 7.2e-06 26.1 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Toprim PF01751.22 EGG01207.1 - 1.9e-06 28.0 0.0 2.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Toprim domain Carboxyl_trans PF01039.22 EGG01208.1 - 4.3e-137 457.8 0.1 5.4e-137 457.4 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 EGG01208.1 - 0.073 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Cutinase PF01083.22 EGG01209.1 - 1.2e-22 80.7 0.0 1.6e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF3089 PF11288.8 EGG01209.1 - 0.0003 20.4 0.0 0.00047 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) VirJ PF06057.11 EGG01209.1 - 0.0037 17.2 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 EGG01209.1 - 0.0071 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 PE-PPE domain Hydrolase_4 PF12146.8 EGG01209.1 - 0.037 13.3 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGG01209.1 - 0.066 13.3 0.0 0.094 12.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain S1 PF00575.23 EGG01210.1 - 9.2e-15 54.8 0.0 1.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 EGG01210.1 - 8.5e-14 51.7 0.0 1.6e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 EGG01210.1 - 2.3e-05 24.6 0.0 3.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 DUF2254 PF10011.9 EGG01210.1 - 0.042 12.7 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Requiem_N PF14051.6 EGG01211.1 - 0.00082 19.5 0.1 0.0031 17.7 0.0 2.0 1 1 1 2 2 2 1 N-terminal domain of DPF2/REQ. CxC1 PF18802.1 EGG01213.1 - 2.6e-22 78.9 0.0 4.8e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG01213.1 - 0.0099 16.0 0.0 0.029 14.5 0.0 1.8 1 1 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG01213.1 - 0.028 14.3 0.1 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases TMEM171 PF15471.6 EGG01216.1 - 0.18 10.7 5.1 0.52 9.2 5.1 1.8 1 0 0 1 1 1 0 Transmembrane protein family 171 Apis_Csd PF11671.8 EGG01216.1 - 1.1 9.3 24.2 0.13 12.3 6.2 2.7 3 0 0 3 3 3 0 Complementary sex determiner protein DUF572 PF04502.13 EGG01216.1 - 3.4 7.2 30.3 5.5 6.5 30.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Cytochrom_B558a PF05038.13 EGG01216.1 - 7.2 6.1 5.6 15 5.1 5.6 1.5 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Sortilin-Vps10 PF15902.5 EGG01217.1 - 9.9e-300 993.6 8.0 7e-158 526.1 0.2 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EGG01217.1 - 1.5e-91 305.3 19.8 9.3e-50 169.3 6.9 2.5 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EGG01217.1 - 2.6e-08 32.6 39.5 0.75 10.0 1.0 11.5 10 0 0 10 10 10 4 BNR/Asp-box repeat CHB_HEX_C PF03174.13 EGG01217.1 - 0.0071 16.3 7.6 4 7.5 0.0 6.3 7 1 0 7 7 7 1 Chitobiase/beta-hexosaminidase C-terminal domain UCR_UQCRX_QCR9 PF05365.12 EGG01217.1 - 2.5 8.1 4.7 24 5.0 0.3 2.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Spiralin PF05215.13 EGG01218.1 - 0.06 12.7 0.0 0.066 12.5 0.0 1.0 1 0 0 1 1 1 0 Spiralin NTF2 PF02136.20 EGG01220.1 - 0.00079 20.0 0.9 0.0018 18.8 0.9 1.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_3 PF13474.6 EGG01220.1 - 0.043 14.1 0.0 0.053 13.8 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Hamartin PF04388.12 EGG01221.1 - 3.8 6.1 15.0 4.6 5.8 15.0 1.1 1 0 0 1 1 1 0 Hamartin protein Pro-kuma_activ PF09286.11 EGG01224.1 - 1.4e-25 90.2 0.0 2.4e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGG01224.1 - 7.1e-06 25.5 0.2 1.1e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 Subtilase family Syntaxin_2 PF14523.6 EGG01225.1 - 1e-24 86.8 9.7 5.5e-24 84.5 2.0 2.5 3 0 0 3 3 3 2 Syntaxin-like protein SNARE PF05739.19 EGG01225.1 - 2.6e-13 49.7 0.9 7.2e-13 48.3 0.9 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EGG01225.1 - 6.5e-05 22.7 10.5 0.0004 20.1 10.5 2.4 1 1 0 1 1 1 1 Syntaxin Gly-rich_Ago1 PF12764.7 EGG01225.1 - 0.022 15.5 2.9 1.1 10.1 0.0 2.9 3 0 0 3 3 3 0 Glycine-rich region of argonaut DUF16 PF01519.16 EGG01225.1 - 0.1 13.1 0.3 0.1 13.1 0.3 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF3657 PF12394.8 EGG01225.1 - 0.15 12.7 0.1 2.5 8.7 0.0 2.9 2 2 0 3 3 3 0 Protein FAM135 DUF1664 PF07889.12 EGG01225.1 - 0.39 10.8 5.7 0.15 12.1 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Synaptobrevin PF00957.21 EGG01225.1 - 0.58 10.0 4.7 0.86 9.4 2.1 2.5 2 1 0 2 2 2 0 Synaptobrevin ABC2_membrane PF01061.24 EGG01226.1 - 1.6e-73 246.6 62.4 2.7e-40 138.1 28.6 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGG01226.1 - 4.4e-33 114.7 0.0 1.7e-15 57.7 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EGG01226.1 - 2e-29 101.3 12.3 6.1e-24 83.7 0.1 3.7 4 0 0 4 4 4 2 CDR ABC transporter AAA_21 PF13304.6 EGG01226.1 - 2.5e-05 24.2 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EGG01226.1 - 0.00085 19.0 0.2 0.013 15.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EGG01226.1 - 0.00097 18.3 17.2 0.00097 18.3 17.2 3.3 3 0 0 3 3 3 1 ABC-2 family transporter protein MMR_HSR1 PF01926.23 EGG01226.1 - 0.001 19.2 0.4 0.92 9.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EGG01226.1 - 0.0013 18.4 0.1 0.016 15.0 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG01226.1 - 0.0018 18.2 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EGG01226.1 - 0.008 15.6 0.0 0.29 10.5 0.0 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_trans_N PF14510.6 EGG01226.1 - 0.013 16.1 0.0 0.028 15.0 0.0 1.6 1 0 0 1 1 1 0 ABC-transporter N-terminal AAA_28 PF13521.6 EGG01226.1 - 0.041 14.1 0.1 0.088 13.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG01226.1 - 0.044 14.2 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EGG01226.1 - 0.054 13.6 0.0 0.19 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGG01226.1 - 0.072 13.6 0.0 0.27 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGG01226.1 - 0.2 11.9 0.1 0.6 10.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGG01226.1 - 0.22 12.0 0.0 0.46 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Voldacs PF03517.13 EGG01229.1 - 4.9e-25 88.3 0.1 7.7e-25 87.6 0.1 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Response_reg PF00072.24 EGG01232.1 - 1.1e-20 73.8 0.1 3.4e-20 72.3 0.1 1.8 1 1 0 1 1 1 1 Response regulator receiver domain 60KD_IMP PF02096.20 EGG01233.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Peptidase_M24 PF00557.24 EGG01235.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M24 ADIP PF11559.8 EGG01237.1 - 1.1e-07 32.0 16.1 1.1e-07 32.0 16.1 3.2 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding GIT1_C PF12205.8 EGG01237.1 - 0.29 11.3 7.8 0.076 13.1 4.1 1.9 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term ERM PF00769.19 EGG01237.1 - 1.2 8.9 28.1 1.9 8.3 22.1 2.9 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Carb_kinase PF01256.17 EGG01238.1 - 8.1e-55 185.9 0.0 1.2e-54 185.4 0.0 1.3 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 EGG01238.1 - 0.003 17.0 0.0 0.0098 15.3 0.0 1.7 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Pept_tRNA_hydro PF01195.19 EGG01240.1 - 0.039 13.9 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase Orn_DAP_Arg_deC PF00278.22 EGG01240.1 - 0.17 12.2 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF1769 PF08588.10 EGG01241.1 - 8.6e-25 86.7 0.2 1.8e-24 85.7 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Trehalose_PPase PF02358.16 EGG01242.1 - 0.00018 20.7 0.0 0.0099 15.0 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase Sec23_trunk PF04811.15 EGG01243.1 - 6.9e-58 196.1 0.0 1e-57 195.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGG01243.1 - 1.3e-26 92.4 0.1 2.3e-26 91.6 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGG01243.1 - 1.3e-16 61.1 0.0 2.6e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGG01243.1 - 2.5e-14 53.0 1.1 2.5e-14 53.0 1.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGG01243.1 - 2.6e-05 24.1 0.0 5.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat RCC1_2 PF13540.6 EGG01244.1 - 4.4e-24 83.7 16.6 4.7e-07 29.4 0.3 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EGG01244.1 - 9.5e-15 55.0 10.9 0.012 16.2 0.1 7.7 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 EGG01244.1 - 5.5e-06 26.2 0.8 1.5e-05 24.7 0.8 1.8 1 0 0 1 1 1 1 F-box-like RraA-like PF03737.15 EGG01245.1 - 3e-34 118.3 0.0 3.9e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA DNA_pol_phi PF04931.13 EGG01247.1 - 6.2 4.8 10.9 6.7 4.7 10.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi PWI PF01480.17 EGG01248.1 - 1.7e-28 98.7 0.0 2.7e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 PWI domain DUF1003 PF06210.11 EGG01248.1 - 0.04 14.0 0.5 0.078 13.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) PCRF PF03462.18 EGG01250.1 - 5.2e-13 49.3 0.0 1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 EGG01250.1 - 2.2e-12 47.0 0.6 4.1e-12 46.0 0.5 1.6 1 1 0 1 1 1 1 RF-1 domain Alg14 PF08660.11 EGG01254.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like OEP PF02321.18 EGG01255.1 - 0.047 13.5 3.6 0.13 12.1 3.6 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein Reprolysin_3 PF13582.6 EGG01255.1 - 0.39 11.2 1.6 5.9 7.4 0.1 2.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Spore_III_AB PF09548.10 EGG01257.1 - 0.29 11.2 0.0 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Hid1 PF12722.7 EGG01257.1 - 9.9 4.1 24.1 0.39 8.8 16.5 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Sel1 PF08238.12 EGG01258.1 - 5.6e-41 138.1 18.2 2.3e-07 31.3 0.4 8.1 9 0 0 9 9 9 7 Sel1 repeat TPR_6 PF13174.6 EGG01258.1 - 0.0017 18.9 3.9 2 9.2 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat HNH_repeat PF18780.1 EGG01258.1 - 0.13 12.1 1.0 2.5 8.0 0.0 3.3 3 0 0 3 3 3 0 Homing endonuclease repeat Arc_PepC PF06819.11 EGG01258.1 - 0.29 11.3 0.9 0.45 10.7 0.3 1.7 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain PPP4R2 PF09184.11 EGG01259.1 - 1 8.9 9.1 0.98 9.0 9.1 1.1 1 0 0 1 1 1 0 PPP4R2 Sigma70_ner PF04546.13 EGG01259.1 - 1.7 8.5 8.4 1.6 8.6 8.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.10 EGG01259.1 - 1.7 7.9 7.8 1.6 8.0 7.8 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EGG01259.1 - 2.3 6.3 13.8 2.4 6.3 13.8 1.0 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 EGG01259.1 - 7.7 6.5 12.5 11 6.0 12.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Pkinase PF00069.25 EGG01260.1 - 4.9e-69 232.6 0.0 7.7e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG01260.1 - 5.8e-49 166.7 0.0 1.1e-48 165.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG01260.1 - 7.1e-05 21.8 0.0 7.1e-05 21.8 0.0 3.5 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGG01260.1 - 0.00048 19.5 0.1 0.044 13.1 0.0 2.5 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.11 EGG01260.1 - 0.004 16.8 0.0 0.0087 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Haspin_kinase PF12330.8 EGG01260.1 - 2.6 6.9 6.6 7.7 5.3 0.0 2.8 3 0 0 3 3 3 0 Haspin like kinase domain DNA_methylase PF00145.17 EGG01261.1 - 6.4e-18 65.2 1.1 2.1e-17 63.5 0.0 2.4 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase SNF2_N PF00176.23 EGG01261.1 - 1.1e-15 57.3 0.2 1.7e-12 46.7 0.0 2.6 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG01261.1 - 7.3e-07 29.5 0.0 2.6e-06 27.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CENP-B_dimeris PF09026.10 EGG01261.1 - 1 9.8 8.5 4.4 7.8 8.5 2.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GREB1 PF15782.5 EGG01262.1 - 0.0048 14.1 0.7 0.0062 13.8 0.7 1.1 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer ORC6 PF05460.13 EGG01262.1 - 0.11 11.8 5.6 0.25 10.6 5.6 1.6 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SOG2 PF10428.9 EGG01262.1 - 0.76 8.9 8.5 1.2 8.3 8.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Cyclin_C PF02984.19 EGG01263.1 - 0.00065 19.8 0.1 0.00097 19.2 0.1 1.6 1 1 0 1 1 1 1 Cyclin, C-terminal domain zf-H2C2_2 PF13465.6 EGG01265.1 - 0.00039 20.7 6.3 0.0014 19.0 6.3 2.0 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGG01265.1 - 0.0006 20.1 7.3 0.11 13.0 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG01265.1 - 0.042 14.7 9.4 1.5 9.8 0.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGG01265.1 - 9.4 6.4 9.7 0.38 10.8 3.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger CSTF2_hinge PF14327.6 EGG01266.1 - 1.1e-29 102.7 2.8 1.1e-29 102.7 2.8 2.4 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EGG01266.1 - 6.2e-17 61.2 0.0 1.2e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EGG01266.1 - 2.6e-12 46.1 9.8 2.6e-12 46.1 9.8 2.2 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal CDC45 PF02724.14 EGG01267.1 - 0.19 10.0 4.1 0.24 9.6 4.1 1.3 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 EGG01267.1 - 0.61 9.6 12.9 1.2 8.7 12.9 1.4 1 0 0 1 1 1 0 PPP4R2 PTPRCAP PF15713.5 EGG01267.1 - 1.5 9.1 10.0 4.2 7.7 10.0 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 EGG01267.1 - 1.6 8.1 9.8 2.9 7.2 9.8 1.4 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 EGG01267.1 - 2.4 7.4 12.4 3.9 6.7 12.4 1.4 1 0 0 1 1 1 0 NOA36 protein Parathyroid PF01279.17 EGG01268.1 - 0.0004 21.0 6.1 1.3 9.7 5.0 3.7 2 1 1 3 3 3 2 Parathyroid hormone family DPM3 PF08285.11 EGG01268.1 - 0.15 12.3 0.6 7 6.9 0.0 2.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3775 PF12616.8 EGG01268.1 - 0.89 9.6 4.5 1.8 8.6 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3775) BING4CT PF08149.11 EGG01269.1 - 1.1e-22 79.6 0.0 1.1e-22 79.6 0.0 1.7 2 0 0 2 2 2 1 BING4CT (NUC141) domain Myb_DNA-binding PF00249.31 EGG01270.1 - 7.3e-12 45.3 0.2 4.8e-11 42.7 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 EGG01270.1 - 2.6e-06 27.1 7.6 0.00055 19.7 1.2 2.5 2 0 0 2 2 2 2 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 EGG01270.1 - 3.6e-05 23.9 0.0 7.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGG01270.1 - 0.49 10.6 2.1 0.88 9.8 0.1 2.4 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 PHD PF00628.29 EGG01272.1 - 1.9e-09 37.3 8.5 3.5e-09 36.4 8.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGG01272.1 - 0.0032 17.0 4.1 0.0057 16.2 4.1 1.4 1 0 0 1 1 1 1 PHD-finger YscO-like PF16789.5 EGG01272.1 - 0.1 12.6 3.3 0.1 12.6 0.1 2.4 2 0 0 2 2 2 0 YscO-like protein zf-CW PF07496.15 EGG01272.1 - 0.58 10.2 2.3 1.3 9.1 2.3 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Ribonuc_L-PSP PF01042.21 EGG01276.1 - 2e-43 147.3 0.1 2.3e-43 147.1 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Exo_endo_phos PF03372.23 EGG01278.1 - 0.0012 18.4 0.0 0.0046 16.5 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGEF PF00621.20 EGG01281.1 - 4e-34 118.4 0.5 6.8e-34 117.7 0.5 1.4 1 0 0 1 1 1 1 RhoGEF domain EF-hand_4 PF12763.7 EGG01281.1 - 9.6e-14 51.2 0.0 3.3e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_9 PF14604.6 EGG01281.1 - 1e-13 50.9 0.3 1.2e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EGG01281.1 - 2.8e-09 36.4 0.9 2.4e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 SH3 domain WH2 PF02205.20 EGG01281.1 - 6.2e-07 29.0 0.2 1.3e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.11 EGG01281.1 - 1e-06 29.0 36.0 1e-06 29.0 36.0 6.1 2 1 2 4 4 4 2 Domain of unknown function (DUF1720) PH_13 PF16652.5 EGG01281.1 - 1e-05 25.4 1.6 2e-05 24.5 0.0 2.3 3 0 0 3 3 3 1 Pleckstrin homology domain SH3_2 PF07653.17 EGG01281.1 - 0.00031 20.4 0.0 0.19 11.4 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain DUF4559 PF15112.6 EGG01281.1 - 7.4 6.2 6.5 14 5.2 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Glyco_hydro_43 PF04616.14 EGG01282.1 - 3.4e-38 131.6 2.4 4.5e-38 131.2 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Spc24 PF08286.11 EGG01283.1 - 0.049 13.9 0.1 0.07 13.4 0.1 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Ribosomal_L23eN PF03939.13 EGG01284.1 - 1.2e-23 83.0 12.4 3.3e-23 81.6 12.4 1.8 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EGG01284.1 - 6.7e-15 55.2 0.3 6.7e-15 55.2 0.3 2.4 2 2 0 2 2 2 1 Ribosomal protein L23 Pea-VEAacid PF08111.11 EGG01285.1 - 0.044 14.1 1.7 11 6.6 0.2 3.2 3 0 0 3 3 3 0 Pea-VEAacid family Ribosomal_L6e PF01159.19 EGG01286.1 - 2.5e-38 131.0 0.5 3.1e-38 130.7 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L6e Acyl_transf_3 PF01757.22 EGG01288.1 - 7.3e-27 94.3 23.4 1e-26 93.9 23.4 1.2 1 0 0 1 1 1 1 Acyltransferase family p31comet PF06581.12 EGG01288.1 - 0.17 11.0 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding DUF418 PF04235.12 EGG01288.1 - 0.24 11.3 7.8 0.12 12.3 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF418) CxC1 PF18802.1 EGG01290.1 - 1.8e-29 102.0 0.0 3.6e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG01290.1 - 6.8e-05 23.0 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG01290.1 - 0.057 13.3 0.2 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases PBP_GOBP PF01395.22 EGG01290.1 - 0.22 11.7 1.2 18 5.5 0.2 2.3 2 0 0 2 2 2 0 PBP/GOBP family Peptidase_M16 PF00675.20 EGG01293.1 - 4.7e-47 159.7 0.1 9.2e-47 158.8 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGG01293.1 - 5.3e-36 124.4 0.0 1.5e-34 119.6 0.0 2.4 2 0 0 2 2 2 1 Peptidase M16 inactive domain EF-hand_6 PF13405.6 EGG01294.1 - 2.1e-12 45.9 0.6 9.8e-06 25.1 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGG01294.1 - 6.1e-09 36.2 0.3 1.1e-06 29.0 0.1 2.8 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGG01294.1 - 2.1e-08 33.1 1.5 0.00048 19.5 0.1 3.3 3 0 0 3 3 3 2 EF hand DUF2666 PF10869.8 EGG01294.1 - 0.024 14.9 0.0 8.8 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) EF-hand_5 PF13202.6 EGG01294.1 - 0.066 12.7 2.2 0.17 11.4 0.1 2.3 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 EGG01294.1 - 0.13 12.2 3.9 2.4 8.1 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain pair AAA PF00004.29 EGG01295.1 - 2.4e-37 128.3 0.0 4.4e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG01295.1 - 1.2e-07 31.4 0.0 2.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGG01295.1 - 3.3e-07 30.2 0.0 1.8e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGG01295.1 - 2.3e-06 28.1 0.0 4.5e-05 23.9 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGG01295.1 - 4.8e-06 26.6 0.3 0.00021 21.3 0.3 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGG01295.1 - 9.6e-06 25.7 0.0 2.5e-05 24.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 EGG01295.1 - 1.5e-05 25.3 0.3 0.002 18.4 0.3 2.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGG01295.1 - 0.00016 22.0 0.0 0.002 18.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 EGG01295.1 - 0.0002 21.6 0.0 0.00055 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 EGG01295.1 - 0.00026 21.0 0.1 0.0011 18.9 0.1 2.0 1 1 1 2 2 2 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 EGG01295.1 - 0.0006 19.9 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.6 EGG01295.1 - 0.0009 19.4 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGG01295.1 - 0.00094 18.6 0.4 0.0019 17.6 0.1 1.5 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGG01295.1 - 0.00096 19.7 0.0 0.0021 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGG01295.1 - 0.00099 18.9 0.1 0.0021 17.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 EGG01295.1 - 0.0017 17.7 0.0 0.15 11.4 0.0 2.2 1 1 1 2 2 2 1 KaiC TniB PF05621.11 EGG01295.1 - 0.0021 17.5 0.5 1.5 8.2 0.0 2.5 2 1 1 3 3 2 2 Bacterial TniB protein Zeta_toxin PF06414.12 EGG01295.1 - 0.0058 15.9 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 EGG01295.1 - 0.0074 16.2 0.2 0.015 15.2 0.2 1.5 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 EGG01295.1 - 0.011 16.2 0.0 0.027 15.0 0.0 1.8 1 1 0 1 1 1 0 ABC transporter TIP49 PF06068.13 EGG01295.1 - 0.012 14.9 0.3 0.025 13.8 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 EGG01295.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EGG01295.1 - 0.015 14.9 0.1 0.15 11.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.11 EGG01295.1 - 0.02 15.0 0.0 0.069 13.2 0.0 1.8 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_21 PF13304.6 EGG01295.1 - 0.023 14.5 0.2 0.57 9.9 0.1 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_3 PF07726.11 EGG01295.1 - 0.024 14.5 0.0 0.067 13.1 0.0 1.9 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EGG01295.1 - 0.03 14.1 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EGG01295.1 - 0.033 13.7 0.1 0.09 12.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EGG01295.1 - 0.034 14.1 0.5 0.15 12.0 0.0 2.1 2 1 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EGG01295.1 - 0.038 14.2 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGG01295.1 - 0.041 13.6 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 EGG01295.1 - 0.043 14.2 0.2 0.13 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.17 EGG01295.1 - 0.06 12.4 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 EGG01295.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EGG01295.1 - 0.078 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FCH PF00611.23 EGG01295.1 - 0.11 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain HSF_DNA-bind PF00447.17 EGG01296.1 - 5.4e-24 84.6 0.0 7.8e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding PRELI PF04707.14 EGG01300.1 - 8.4e-34 116.7 0.0 2.1e-33 115.4 0.0 1.6 1 1 0 1 1 1 1 PRELI-like family ArdA PF07275.11 EGG01301.1 - 0.14 12.7 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Antirestriction protein (ArdA) Cep57_CLD_2 PF14197.6 EGG01302.1 - 0.0065 16.5 1.9 2 8.6 2.6 2.8 1 1 1 2 2 2 1 Centrosome localisation domain of PPC89 RNA_GG_bind PF10258.9 EGG01302.1 - 0.046 13.8 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 PHAX RNA-binding domain Syntaxin-6_N PF09177.11 EGG01302.1 - 0.063 13.8 1.4 0.19 12.3 1.4 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal SlyX PF04102.12 EGG01302.1 - 1.1 9.9 4.9 3 8.5 3.0 2.5 1 1 1 2 2 2 0 SlyX MutS_V PF00488.21 EGG01303.1 - 1.2e-24 87.4 0.2 1.3e-24 87.3 0.2 1.0 1 0 0 1 1 1 1 MutS domain V DUF615 PF04751.14 EGG01310.1 - 0.061 13.3 2.2 0.074 13.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Peptidase_M16 PF00675.20 EGG01311.1 - 2.1e-39 134.9 0.0 4.7e-39 133.7 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGG01311.1 - 1.9e-17 63.9 0.0 5e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Peptidase M16 inactive domain ORC6 PF05460.13 EGG01314.1 - 1.9 7.7 10.3 2.4 7.3 10.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RE_HindIII PF09518.10 EGG01315.1 - 0.018 14.3 2.3 0.026 13.8 2.3 1.3 1 0 0 1 1 1 0 HindIII restriction endonuclease Peptidase_M16_C PF05193.21 EGG01315.1 - 0.021 14.8 0.3 0.065 13.2 0.0 2.0 3 0 0 3 3 3 0 Peptidase M16 inactive domain DUF4605 PF15378.6 EGG01315.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) Phage_int_SAM_1 PF02899.17 EGG01315.1 - 0.13 12.6 0.1 0.75 10.1 0.0 2.2 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain PolyG_pol PF01518.16 EGG01317.1 - 0.03 13.0 0.1 0.035 12.8 0.1 1.1 1 0 0 1 1 1 0 Sigma NS protein DUF948 PF06103.11 EGG01318.1 - 0.036 14.3 0.3 0.097 12.9 0.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ER_lumen_recept PF00810.18 EGG01323.1 - 6.8e-56 189.2 11.4 9.3e-56 188.7 11.4 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EGG01323.1 - 0.01 15.6 12.7 0.29 10.9 0.1 4.2 5 0 0 5 5 5 0 PQ loop repeat DAHP_synth_2 PF01474.16 EGG01324.1 - 2.2e-176 586.7 0.0 2.6e-176 586.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DAHP_synth_1 PF00793.20 EGG01324.1 - 0.09 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 DAHP synthetase I family Hpt PF01627.23 EGG01325.1 - 6e-08 32.8 0.0 8.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Hpt domain HIT PF01230.23 EGG01326.1 - 1.8e-23 83.1 0.9 2.5e-23 82.7 0.9 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGG01326.1 - 3.1e-12 47.0 0.4 4.4e-12 46.5 0.4 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGG01326.1 - 0.00022 21.1 0.1 0.0003 20.7 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 MAM33 PF02330.16 EGG01327.1 - 5.4e-11 42.8 0.2 0.0067 16.4 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial glycoprotein RNA_pol_Rpb6 PF01192.22 EGG01328.1 - 3.3e-14 52.5 0.0 3.9e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF4549 PF15082.6 EGG01328.1 - 0.15 11.9 0.0 0.16 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Cpn60_TCP1 PF00118.24 EGG01330.1 - 2.1e-161 537.9 2.3 2.4e-161 537.7 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Na_Ca_ex_C PF16494.5 EGG01330.1 - 0.062 13.8 0.5 0.29 11.6 0.0 2.2 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain Piwi PF02171.17 EGG01332.1 - 2.8e-78 263.2 0.0 4e-78 262.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EGG01332.1 - 7.3e-22 78.5 0.2 2.9e-21 76.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EGG01332.1 - 2.7e-09 36.5 0.0 6e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 EGG01332.1 - 2.7e-07 30.5 0.0 5.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EGG01332.1 - 1.1e-05 25.6 0.0 3.5e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 EGG01332.1 - 2.2e-05 24.7 0.1 6.3e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain CENP-L PF13092.6 EGG01332.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 EKLF_TAD1 PF16832.5 EGG01333.1 - 0.11 12.3 0.4 0.34 10.8 0.4 1.8 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 SLC12 PF03522.15 EGG01334.1 - 0.05 12.6 0.1 0.13 11.3 0.1 1.6 1 0 0 1 1 1 0 Solute carrier family 12 CAF20 PF17052.5 EGG01335.1 - 0.23 11.6 2.6 0.77 9.9 0.7 2.3 2 0 0 2 2 2 0 Cap associated factor DSS1_SEM1 PF05160.13 EGG01335.1 - 0.65 10.1 8.9 0.12 12.4 0.5 3.0 3 0 0 3 3 3 0 DSS1/SEM1 family PUFD PF16553.5 EGG01336.1 - 0.01 16.0 0.5 0.026 14.6 0.5 1.6 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain HMG_box PF00505.19 EGG01336.1 - 0.016 15.6 1.7 7.5 7.1 0.1 3.2 3 0 0 3 3 3 0 HMG (high mobility group) box DUF1515 PF07439.11 EGG01336.1 - 0.048 13.7 0.6 0.1 12.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) FancD2 PF14631.6 EGG01336.1 - 0.11 9.9 4.9 0.18 9.2 4.9 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Pox_Ag35 PF03286.14 EGG01336.1 - 3.1 7.6 14.6 7.8 6.2 14.6 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Soyouz_module PF14313.6 EGG01337.1 - 0.42 10.4 5.0 1.3 8.8 1.7 2.5 1 1 1 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Presenilin PF01080.17 EGG01337.1 - 3.1 6.5 7.8 3.5 6.3 7.8 1.0 1 0 0 1 1 1 0 Presenilin OGFr_N PF04664.13 EGG01338.1 - 0.047 13.2 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region Mob1_phocein PF03637.17 EGG01339.1 - 4e-28 98.6 0.3 6.9e-28 97.8 0.3 1.3 1 0 0 1 1 1 1 Mob1/phocein family Cwf_Cwc_15 PF04889.12 EGG01339.1 - 8.9 6.0 16.2 12 5.6 16.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF356 PF04009.12 EGG01340.1 - 0.065 13.5 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF356) DUF356 PF04009.12 EGG01341.1 - 0.065 13.5 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF356) Ribosomal_L36e PF01158.18 EGG01342.1 - 6.1e-40 135.4 3.1 7e-40 135.2 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.6 EGG01342.1 - 0.054 13.6 0.1 0.065 13.4 0.1 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MCM6_C PF18263.1 EGG01343.1 - 0.083 13.1 0.0 0.09 13.0 0.0 1.1 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pkinase PF00069.25 EGG01344.1 - 6.3e-67 225.7 0.0 8.3e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG01344.1 - 7.7e-42 143.4 0.0 2.9e-41 141.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG01344.1 - 1.9e-06 27.4 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG01344.1 - 0.0048 16.3 0.1 0.0083 15.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGG01344.1 - 0.079 12.6 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGG01344.1 - 0.26 10.0 2.8 1 8.0 2.8 1.9 1 1 0 1 1 1 0 Fungal protein kinase Macoilin PF09726.9 EGG01344.1 - 0.49 8.9 2.4 0.52 8.8 2.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF1970 PF09301.10 EGG01350.1 - 0.0098 16.1 1.5 0.018 15.3 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1970) S-AdoMet_synt_C PF02773.16 EGG01351.1 - 3.1e-65 218.3 0.2 8.4e-65 216.9 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EGG01351.1 - 1.5e-45 154.4 0.0 2.5e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EGG01351.1 - 8.6e-44 148.3 0.0 2e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EGG01351.1 - 0.021 13.6 0.1 0.14 10.9 0.1 2.1 2 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) SIP1 PF04938.12 EGG01352.1 - 4.7e-23 82.1 0.0 6.6e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF3226 PF11536.8 EGG01353.1 - 0.0086 15.8 2.4 0.014 15.1 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) SURF6 PF04935.12 EGG01353.1 - 0.01 15.7 1.7 0.01 15.7 1.7 1.5 2 0 0 2 2 2 0 Surfeit locus protein 6 Fib_alpha PF08702.10 EGG01353.1 - 0.11 12.7 4.1 0.23 11.6 4.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HSBP1 PF06825.12 EGG01353.1 - 0.72 9.8 5.9 16 5.4 2.0 2.7 2 1 0 2 2 2 0 Heat shock factor binding protein 1 DUF4094 PF13334.6 EGG01353.1 - 1.5 9.3 5.3 36 4.9 1.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) TolA_bind_tri PF16331.5 EGG01353.1 - 2.3 8.4 10.2 4.4 7.4 5.9 2.6 2 1 0 2 2 2 0 TolA binding protein trimerisation Mannosyl_trans PF05007.13 EGG01354.1 - 5.7e-74 249.3 24.3 8.9e-74 248.6 24.3 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EGG01354.1 - 1.2e-08 34.4 29.7 1.2e-08 34.4 29.7 1.6 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EGG01354.1 - 3.3e-06 27.0 1.7 3.3e-06 27.0 1.7 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 87 R3H-assoc PF13902.6 EGG01355.1 - 0.024 15.0 0.2 0.024 15.0 0.2 1.9 2 0 0 2 2 2 0 R3H-associated N-terminal domain 2OG-FeII_Oxy_2 PF13532.6 EGG01356.1 - 1.1e-06 29.0 0.0 6.2e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIG-Y PF15159.6 EGG01357.1 - 3.3e-11 43.9 1.5 3.3e-11 43.9 1.5 1.7 2 0 0 2 2 2 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y ATP-synt_E PF05680.12 EGG01358.1 - 2.4e-15 56.7 0.0 2.5e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain Cation_efflux PF01545.21 EGG01359.1 - 5.1e-56 189.6 3.3 6.9e-56 189.1 3.3 1.2 1 0 0 1 1 1 1 Cation efflux family NPCC PF08058.11 EGG01359.1 - 2.7 8.1 4.4 10 6.2 1.1 2.4 2 0 0 2 2 2 0 Nuclear pore complex component zf-H2C2_2 PF13465.6 EGG01360.1 - 0.00047 20.5 6.3 0.0016 18.8 6.3 2.0 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGG01360.1 - 0.00074 19.8 7.3 0.12 12.8 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG01360.1 - 0.051 14.4 9.4 1.8 9.6 0.8 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Cytochrom_B559a PF00284.20 EGG01361.1 - 0.0025 17.5 0.1 0.069 12.9 0.2 2.1 1 1 1 2 2 2 1 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Plasmodium_HRP PF05403.11 EGG01361.1 - 0.11 12.3 28.5 0.12 12.1 28.5 1.1 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) FAT PF02259.23 EGG01362.1 - 1.3e-116 389.7 4.7 1.3e-116 389.7 4.7 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EGG01362.1 - 1.2e-64 218.6 0.1 2.3e-64 217.6 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EGG01362.1 - 1.3e-51 174.8 5.5 2.1e-48 164.3 0.0 5.3 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EGG01362.1 - 4.7e-42 142.4 0.2 3.2e-41 139.7 0.0 2.7 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EGG01362.1 - 4.5e-15 55.8 15.4 0.011 16.2 0.0 8.9 7 2 2 9 9 9 5 HEAT repeats FATC PF02260.20 EGG01362.1 - 3.8e-14 52.2 3.9 7e-14 51.3 0.3 3.1 3 0 0 3 3 3 1 FATC domain HEAT PF02985.22 EGG01362.1 - 3.6e-13 48.5 18.2 0.22 11.9 0.0 11.2 11 0 0 11 11 10 4 HEAT repeat Cnd1 PF12717.7 EGG01362.1 - 7.3e-07 29.4 1.0 0.23 11.5 0.0 4.9 3 1 2 5 5 4 3 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 EGG01362.1 - 0.00075 19.4 2.1 1.7 8.5 0.0 5.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ PF13513.6 EGG01362.1 - 0.0015 19.0 31.7 0.12 12.9 0.1 10.9 11 2 3 14 14 13 3 HEAT-like repeat IFRD PF05004.13 EGG01362.1 - 0.015 14.4 5.4 1.1 8.3 0.0 4.7 5 1 1 6 6 6 0 Interferon-related developmental regulator (IFRD) TPR_19 PF14559.6 EGG01362.1 - 0.018 15.5 0.0 8.3 7.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ParcG PF10274.9 EGG01362.1 - 0.033 14.3 7.8 5.6 7.0 0.1 4.7 3 1 1 4 4 4 0 Parkin co-regulated protein Cohesin_HEAT PF12765.7 EGG01362.1 - 0.035 14.4 6.1 13 6.2 0.2 4.9 3 1 1 4 4 4 0 HEAT repeat associated with sister chromatid cohesion UME PF08064.13 EGG01362.1 - 0.092 12.7 10.4 34 4.4 0.0 7.3 6 2 2 8 8 8 0 UME (NUC010) domain zf-UBR PF02207.20 EGG01366.1 - 0.0012 19.0 3.6 0.0024 18.0 3.6 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) DUF3716 PF12511.8 EGG01366.1 - 0.021 14.9 2.9 0.021 14.9 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) CAF1C_H4-bd PF12265.8 EGG01367.1 - 1.9e-26 92.1 1.0 4.3e-26 90.9 1.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGG01367.1 - 2.9e-23 81.7 18.1 8.4e-05 23.3 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.11 EGG01367.1 - 0.0016 18.3 0.1 0.005 16.8 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EGG01367.1 - 0.0025 18.1 0.8 0.15 12.4 0.2 3.7 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PAT1 PF09770.9 EGG01368.1 - 0.033 12.5 14.8 0.047 12.0 14.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1062 PF06353.12 EGG01370.1 - 0.0029 18.4 7.3 0.0047 17.7 7.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1062) ArfGap PF01412.18 EGG01370.1 - 0.88 9.7 7.3 0.75 9.9 3.8 2.1 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DUF1451 PF07295.11 EGG01370.1 - 1.6 8.7 8.8 9.5 6.2 4.5 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain Dis3l2_C_term PF17877.1 EGG01370.1 - 4.2 7.8 9.9 1.1 9.6 3.4 2.1 1 1 1 2 2 2 0 DIS3-like exonuclease 2 C terminal Amidase PF01425.21 EGG01371.1 - 4.1e-100 335.9 0.0 5.2e-100 335.5 0.0 1.1 1 0 0 1 1 1 1 Amidase F-box-like PF12937.7 EGG01372.1 - 3.5e-05 23.6 0.1 0.00014 21.7 0.0 2.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 EGG01372.1 - 0.19 11.7 2.2 2.3 8.2 2.1 2.8 2 1 0 2 2 2 0 F-box domain Ribosomal_S10 PF00338.22 EGG01374.1 - 5.2e-20 71.5 0.0 5.8e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Alpha_kinase PF02816.18 EGG01376.1 - 2.1e-09 37.8 0.0 3.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family TPMT PF05724.11 EGG01379.1 - 4.7e-34 118.0 0.0 5.4e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EGG01379.1 - 3.2e-08 34.2 0.0 4.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG01379.1 - 3.6e-08 33.3 0.0 5e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG01379.1 - 7.1e-06 26.7 0.0 9.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG01379.1 - 1e-05 26.1 0.0 1.4e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG01379.1 - 0.0014 18.5 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGG01379.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Pox_MCEL PF03291.16 EGG01379.1 - 0.064 12.4 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme WD40 PF00400.32 EGG01380.1 - 0.0035 18.2 0.6 2 9.4 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Cwf_Cwc_15 PF04889.12 EGG01380.1 - 1.6 8.4 4.9 2.2 7.9 4.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Abhydrolase_1 PF00561.20 EGG01384.1 - 0.00039 20.1 0.1 0.0013 18.4 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Lipase_2 PF01674.18 EGG01384.1 - 0.0016 18.0 0.3 0.013 15.0 0.3 2.0 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.7 EGG01384.1 - 0.0019 18.8 0.0 0.0024 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 EGG01384.1 - 0.0058 15.8 0.0 0.0091 15.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 EGG01384.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EGG01384.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGG01384.1 - 0.04 13.8 0.0 0.077 12.8 0.0 1.4 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Lipase_2 PF01674.18 EGG01385.1 - 0.00021 20.9 0.1 0.00087 18.9 0.1 2.0 1 1 0 1 1 1 1 Lipase (class 2) Palm_thioest PF02089.15 EGG01385.1 - 0.0033 17.3 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF900 PF05990.12 EGG01385.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 EGG01385.1 - 0.026 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase bMG1 PF17970.1 EGG01385.1 - 0.029 14.4 0.1 7 6.8 0.1 2.6 3 0 0 3 3 3 0 Bacterial Alpha-2-macroglobulin MG1 domain DUF676 PF05057.14 EGG01385.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) 3HCDH_N PF02737.18 EGG01390.1 - 5.1e-57 192.7 0.3 8.1e-57 192.0 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGG01390.1 - 2.8e-32 111.2 0.0 6.1e-32 110.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGG01390.1 - 0.0001 22.5 2.0 0.003 17.7 2.0 2.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 EGG01390.1 - 0.00044 19.6 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EGG01390.1 - 0.026 15.0 0.0 0.35 11.3 0.0 2.2 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 EGG01390.1 - 0.052 12.8 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EGG01390.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AMP-binding PF00501.28 EGG01391.1 - 5.1e-98 328.4 0.0 6.4e-98 328.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG01391.1 - 1.7e-06 28.9 0.0 5.1e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cullin PF00888.22 EGG01393.1 - 2.9e-182 607.6 17.9 4.2e-182 607.0 17.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGG01393.1 - 1.9e-27 95.1 2.9 5.7e-27 93.5 2.1 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Glutaminase PF04960.15 EGG01393.1 - 0.095 11.9 0.4 0.2 10.8 0.4 1.5 1 0 0 1 1 1 0 Glutaminase PP1_bind PF15276.6 EGG01394.1 - 3.5 8.0 14.8 7.8 6.9 0.7 4.5 3 1 2 5 5 5 0 Protein phosphatase 1 binding Kinesin PF00225.23 EGG01395.1 - 2.4e-79 266.7 0.0 4.8e-79 265.7 0.0 1.4 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGG01395.1 - 2.4e-17 63.2 0.1 1.2e-16 61.0 0.0 2.1 3 0 0 3 3 3 1 Microtubule binding Metallophos PF00149.28 EGG01396.1 - 4.9e-10 40.2 0.0 9.9e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG01396.1 - 2.4e-08 34.3 0.0 4.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EGG01396.1 - 0.062 12.6 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily ThiF PF00899.21 EGG01398.1 - 5e-47 160.3 0.0 7.4e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EGG01398.1 - 0.0023 18.0 0.1 0.0037 17.3 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 EGG01398.1 - 0.0064 16.1 0.2 0.0099 15.5 0.2 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGG01398.1 - 0.0064 16.7 0.0 0.014 15.7 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EGG01398.1 - 0.031 14.7 0.0 0.052 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.24 EGG01398.1 - 0.035 13.7 0.4 0.051 13.2 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG01398.1 - 0.14 11.4 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGG01398.1 - 0.18 11.0 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Arf PF00025.21 EGG01399.1 - 1.3e-43 148.4 0.0 1.6e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGG01399.1 - 1.2e-19 70.5 0.0 1.3e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG01399.1 - 1.4e-17 64.0 0.0 2.1e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGG01399.1 - 2.1e-09 37.0 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGG01399.1 - 7.9e-08 32.4 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGG01399.1 - 1.1e-07 31.5 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGG01399.1 - 1.1e-06 28.0 1.1 4e-05 23.0 0.1 2.3 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 EGG01399.1 - 0.0019 18.3 0.2 0.097 12.7 0.4 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 EGG01399.1 - 0.011 15.3 1.0 0.04 13.4 1.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 EGG01399.1 - 0.013 15.0 0.2 0.02 14.4 0.2 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NOG1 PF06858.14 EGG01399.1 - 0.047 13.5 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) RsgA_GTPase PF03193.16 EGG01399.1 - 0.12 12.3 0.1 9.5 6.1 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase Peptidase_S46 PF10459.9 EGG01401.1 - 1.1 7.8 17.3 1.5 7.4 17.3 1.1 1 0 0 1 1 1 0 Peptidase S46 Zeta_toxin PF06414.12 EGG01402.1 - 0.076 12.3 0.0 0.095 12.0 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin Glyco_hydro_7 PF00840.20 EGG01404.1 - 1.9e-202 672.8 10.8 2.1e-202 672.6 10.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_7 PF00840.20 EGG01405.1 - 1.3e-203 676.6 12.0 1.5e-203 676.4 12.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DOT1 PF08123.13 EGG01406.1 - 0.0022 17.5 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Na_H_Exchanger PF00999.21 EGG01407.1 - 5.9e-63 212.9 30.3 7.5e-63 212.6 30.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Phage_holin_8 PF16931.5 EGG01407.1 - 0.31 11.0 5.3 0.82 9.7 2.0 2.8 3 0 0 3 3 3 0 Putative phage holin DUF515 PF04415.12 EGG01408.1 - 0.99 7.7 5.3 1.5 7.1 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) tRNA_anti-codon PF01336.25 EGG01409.1 - 0.084 12.9 0.0 9.5 6.3 0.0 2.7 2 1 0 2 2 2 0 OB-fold nucleic acid binding domain SH3_1 PF00018.28 EGG01412.1 - 5.7e-10 38.6 0.3 9.6e-10 37.9 0.3 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG01412.1 - 1.9e-06 27.5 0.0 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGG01412.1 - 3.8e-06 26.7 0.1 6.7e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 EGG01412.1 - 0.087 12.6 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) CxC6 PF18721.1 EGG01414.1 - 0.0088 16.3 0.7 0.017 15.4 0.0 1.9 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases ATS3 PF06232.11 EGG01414.1 - 0.024 14.5 0.2 0.61 10.0 0.0 2.2 1 1 1 2 2 2 0 Embryo-specific protein 3, (ATS3) NOD2_WH PF17779.1 EGG01415.1 - 0.16 12.3 0.3 0.42 11.0 0.2 1.7 2 0 0 2 2 2 0 NOD2 winged helix domain TAP42 PF04177.12 EGG01417.1 - 0.051 12.7 1.7 0.098 11.8 1.7 1.4 1 0 0 1 1 1 0 TAP42-like family MRP-S33 PF08293.11 EGG01417.1 - 0.16 12.2 1.0 2 8.7 0.0 2.5 2 1 0 2 2 2 0 Mitochondrial ribosomal subunit S27 Spindle_Spc25 PF08234.12 EGG01419.1 - 8.7e-21 73.9 1.4 8.7e-21 73.9 1.4 2.4 3 0 0 3 3 3 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 EGG01419.1 - 0.00016 20.7 15.6 0.00021 20.3 15.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 EGG01419.1 - 0.0035 16.1 9.7 0.0044 15.7 9.7 1.1 1 0 0 1 1 1 1 AAA domain Atg14 PF10186.9 EGG01419.1 - 0.098 11.7 10.1 0.13 11.3 10.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EGG01419.1 - 0.12 11.6 8.1 0.17 11.1 8.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Ribosomal_S2 PF00318.20 EGG01419.1 - 0.34 10.1 3.1 0.53 9.5 3.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 IL15 PF02372.15 EGG01419.1 - 0.47 10.5 4.7 0.96 9.5 4.1 1.8 1 1 1 2 2 2 0 Interleukin 15 ALMT PF11744.8 EGG01419.1 - 3.8 6.2 9.6 4.6 6.0 9.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DOT1 PF08123.13 EGG01420.1 - 5.7e-56 189.3 0.0 8.3e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.19 EGG01420.1 - 0.079 12.7 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Glyco_hydro_10 PF00331.20 EGG01421.1 - 7.6e-05 22.0 0.0 7.6e-05 22.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_trans_1_4 PF13692.6 EGG01422.1 - 8.7e-08 32.7 0.0 1.5e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGG01422.1 - 2e-07 30.7 0.0 4e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGG01422.1 - 0.0021 18.4 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 RRM_1 PF00076.22 EGG01423.1 - 1.7e-85 280.8 0.5 1.5e-21 76.0 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EGG01423.1 - 1.6e-27 95.5 1.0 3.3e-27 94.5 1.0 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 EGG01423.1 - 1.8e-05 24.7 0.0 0.14 12.3 0.0 4.1 4 1 0 4 4 4 1 RNA recognition motif DUF4523 PF15023.6 EGG01423.1 - 0.00035 20.4 0.0 0.95 9.3 0.0 3.9 2 2 2 4 4 4 1 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 EGG01423.1 - 0.0004 20.2 0.0 0.043 13.7 0.0 3.4 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EGG01423.1 - 0.00042 20.3 1.7 0.13 12.3 0.3 3.9 3 1 1 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.6 EGG01423.1 - 0.011 15.7 2.2 55 3.9 0.0 4.6 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif YflT PF11181.8 EGG01423.1 - 0.053 14.0 1.7 0.39 11.3 1.1 2.4 2 0 0 2 2 2 0 Heat induced stress protein YflT Trypsin_2 PF13365.6 EGG01424.1 - 4.8e-09 37.3 0.0 7.9e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGG01424.1 - 0.00024 21.0 0.0 0.00053 19.9 0.0 1.5 1 1 0 1 1 1 1 Trypsin Peptidase_S29 PF02907.15 EGG01424.1 - 0.017 14.8 0.0 0.046 13.5 0.0 1.6 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease DUF543 PF04418.12 EGG01425.1 - 0.053 13.5 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF543) DUF1689 PF07954.11 EGG01425.1 - 0.053 13.9 0.0 0.07 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) PCI PF01399.27 EGG01426.1 - 3.9e-05 24.1 0.3 0.0001 22.7 0.1 2.0 2 0 0 2 2 2 1 PCI domain DUF3646 PF12362.8 EGG01426.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal FlxA PF14282.6 EGG01426.1 - 0.097 12.7 3.1 0.23 11.5 3.1 1.6 1 0 0 1 1 1 0 FlxA-like protein eIF3m_C_helix PF18005.1 EGG01426.1 - 0.16 11.7 0.2 0.47 10.2 0.2 1.8 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix LigA PF07746.11 EGG01427.1 - 0.16 12.1 0.1 0.41 10.8 0.1 1.6 1 0 0 1 1 1 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit Inhibitor_I9 PF05922.16 EGG01428.1 - 0.00028 21.5 0.4 0.00081 20.0 0.4 1.9 1 1 0 1 1 1 1 Peptidase inhibitor I9 B PF02216.16 EGG01428.1 - 0.095 12.7 2.3 12 6.0 0.1 3.5 4 0 0 4 4 4 0 B domain Med13_C PF06333.12 EGG01428.1 - 1.2 8.3 6.4 1.5 8.0 6.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Glyco_hydro_10 PF00331.20 EGG01430.1 - 5.5e-93 311.6 0.0 6.8e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 L51_S25_CI-B8 PF05047.16 EGG01431.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Asp4 PF16996.5 EGG01432.1 - 0.52 10.1 2.0 1.1 9.1 2.0 1.5 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 DUF1515 PF07439.11 EGG01433.1 - 0.32 11.0 3.4 4.5 7.3 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Flagellin_C PF00700.21 EGG01433.1 - 0.6 10.5 7.9 7 7.1 0.7 3.3 2 1 1 3 3 3 0 Bacterial flagellin C-terminal helical region Glu-tRNAGln PF02686.15 EGG01433.1 - 1.1 9.6 6.1 1.8 9.0 0.1 3.5 3 1 1 4 4 4 0 Glu-tRNAGln amidotransferase C subunit Laminin_II PF06009.12 EGG01433.1 - 3.7 7.5 14.5 1.4 8.9 4.3 2.5 1 1 1 2 2 2 0 Laminin Domain II XhlA PF10779.9 EGG01433.1 - 3.9 7.8 9.5 2.2 8.5 1.3 3.4 3 0 0 3 3 3 0 Haemolysin XhlA Exo_endo_phos PF03372.23 EGG01434.1 - 3.5e-07 30.0 0.0 7.5e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 EGG01434.1 - 0.0088 16.9 2.2 0.06 14.3 1.1 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat RNA_lig_T4_1 PF09511.10 EGG01435.1 - 1.8e-71 240.5 0.0 3.5e-71 239.6 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 EGG01435.1 - 1.1e-22 80.7 0.0 3.4e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 EGG01435.1 - 1.9e-20 73.6 0.0 5.8e-14 52.5 0.0 2.9 2 1 1 3 3 3 2 tRNA ligase kinase domain DPBB_1 PF03330.18 EGG01436.1 - 4.9e-09 36.4 0.0 9e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EGG01436.1 - 0.0065 16.3 0.0 0.01 15.7 0.0 1.3 1 1 0 1 1 1 1 Barwin family UPF1_Zn_bind PF09416.10 EGG01437.1 - 2.1e-68 229.1 0.2 8.8e-68 227.1 0.2 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) DUF5599 PF18141.1 EGG01437.1 - 6.9e-35 119.2 0.0 1.4e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_11 PF13086.6 EGG01437.1 - 5.4e-21 75.5 0.8 5.4e-21 75.5 0.8 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGG01437.1 - 1.8e-11 44.1 0.0 3.7e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG01437.1 - 1.2e-09 38.7 0.3 2.7e-09 37.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 EGG01437.1 - 4.6e-05 23.5 0.0 7.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EGG01437.1 - 0.00071 19.5 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 EGG01437.1 - 0.00078 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 EGG01437.1 - 0.002 17.4 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 EGG01437.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 EGG01437.1 - 0.03 14.6 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EGG01437.1 - 0.043 13.6 0.1 0.066 13.0 0.1 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.16 EGG01437.1 - 0.056 12.9 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 EGG01437.1 - 0.057 12.5 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 EGG01437.1 - 0.094 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGG01437.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.7 EGG01437.1 - 0.16 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Ribosomal_S27e PF01667.17 EGG01437.1 - 0.93 9.3 7.1 0.091 12.5 2.4 1.7 2 0 0 2 2 1 0 Ribosomal protein S27 Cation_efflux PF01545.21 EGG01439.1 - 1.5e-51 175.0 0.2 1.8e-51 174.7 0.2 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 EGG01439.1 - 3.6e-07 29.7 24.8 9.7e-06 25.0 19.3 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter V_ATPase_I PF01496.19 EGG01439.1 - 0.016 13.2 3.1 0.02 12.8 3.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CxC6 PF18721.1 EGG01440.1 - 8.7e-15 54.8 3.7 8.7e-15 54.8 3.7 2.2 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 EGG01440.1 - 0.004 17.2 0.5 0.004 17.2 0.5 2.3 3 0 0 3 3 3 1 CxC5 like cysteine cluster associated with KDZ transposases Prenyltrans PF00432.21 EGG01441.1 - 3.9e-57 189.7 3.5 6.2e-12 45.1 0.1 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EGG01441.1 - 0.00084 18.5 0.2 0.27 10.3 0.0 2.7 1 1 2 3 3 3 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EGG01441.1 - 0.057 12.5 0.4 0.14 11.3 0.1 1.7 1 1 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain CcmD PF04995.14 EGG01441.1 - 0.17 12.0 1.0 0.36 11.0 1.0 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) BRCT PF00533.26 EGG01442.1 - 7.9e-08 32.6 0.2 3e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGG01442.1 - 3.4e-07 30.6 0.2 9.9e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGG01442.1 - 1e-06 28.6 0.1 2.6e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 EGG01442.1 - 4.1e-06 27.0 0.7 4.6e-05 23.6 0.0 2.5 1 1 1 2 2 2 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EGG01442.1 - 0.034 14.2 0.1 0.06 13.4 0.1 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Macoilin PF09726.9 EGG01442.1 - 0.37 9.3 7.3 0.38 9.3 7.3 1.1 1 0 0 1 1 1 0 Macoilin family DSPc PF00782.20 EGG01443.1 - 1e-05 25.3 0.0 3.6e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EGG01443.1 - 0.00011 22.0 0.1 0.00019 21.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 EGG01443.1 - 0.00094 19.3 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF442 PF04273.13 EGG01443.1 - 0.093 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative phosphatase (DUF442) bZIP_1 PF00170.21 EGG01444.1 - 0.00012 22.1 9.7 0.00012 22.1 9.7 2.4 2 0 0 2 2 2 1 bZIP transcription factor ATG16 PF08614.11 EGG01444.1 - 0.0056 16.9 5.1 0.0056 16.9 5.1 3.1 4 1 0 4 4 4 1 Autophagy protein 16 (ATG16) Alpha_kinase PF02816.18 EGG01446.1 - 3.8e-15 56.5 0.0 5.6e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family Arginosuc_synth PF00764.19 EGG01447.1 - 1.1e-144 482.5 0.0 1.3e-144 482.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EGG01447.1 - 0.00032 20.3 0.0 0.00054 19.5 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EGG01447.1 - 0.0075 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase bZIP_1 PF00170.21 EGG01448.1 - 1.1e-09 38.2 11.8 2.9e-09 36.9 11.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 EGG01448.1 - 0.0017 18.1 5.7 0.0017 18.1 5.7 2.4 3 0 0 3 3 3 1 SWI5-dependent HO expression protein 3 YabA PF06156.13 EGG01448.1 - 0.025 15.2 0.5 0.025 15.2 0.5 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Lyase_aromatic PF00221.19 EGG01448.1 - 0.085 11.5 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Aromatic amino acid lyase DUF812 PF05667.11 EGG01448.1 - 0.19 10.6 13.3 0.35 9.7 13.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TSC22 PF01166.18 EGG01448.1 - 0.23 11.8 2.5 0.55 10.6 2.5 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family GCN5L1 PF06320.13 EGG01448.1 - 0.52 10.5 4.7 1.5 9.0 4.7 1.8 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) bZIP_2 PF07716.15 EGG01448.1 - 0.81 9.8 18.0 0.63 10.2 13.4 2.3 1 1 1 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 EGG01448.1 - 0.85 9.4 4.6 1.8 8.4 4.6 1.5 1 0 0 1 1 1 0 Septum formation initiator Glucosamine_iso PF01182.20 EGG01450.1 - 8e-71 238.5 0.0 9.6e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ras PF00071.22 EGG01451.1 - 4.3e-52 176.0 0.1 1.2e-51 174.6 0.1 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG01451.1 - 4.2e-31 107.7 0.1 1.2e-29 103.0 0.1 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG01451.1 - 2e-10 40.4 0.0 4.4e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG01451.1 - 2.9e-07 30.6 0.0 5.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG01451.1 - 2.6e-06 27.1 0.0 4.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGG01451.1 - 4.9e-05 22.8 0.0 9e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGG01451.1 - 0.00029 20.8 0.0 0.0046 16.9 0.0 2.2 2 1 0 2 2 2 1 RsgA GTPase Septin PF00735.18 EGG01451.1 - 0.0023 17.3 0.1 0.023 14.0 0.0 2.0 2 0 0 2 2 2 1 Septin PduV-EutP PF10662.9 EGG01451.1 - 0.0056 16.4 0.2 0.15 11.8 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EGG01451.1 - 0.0068 16.7 0.1 0.013 15.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 EGG01451.1 - 0.016 15.0 0.1 0.77 9.5 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EGG01451.1 - 0.023 15.2 0.0 0.037 14.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EGG01451.1 - 0.025 15.0 0.0 0.025 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EGG01451.1 - 0.026 14.1 0.1 0.046 13.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGG01451.1 - 0.026 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGG01451.1 - 0.052 13.5 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SRPRB PF09439.10 EGG01451.1 - 0.086 12.3 0.0 0.19 11.1 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 EGG01451.1 - 0.097 12.6 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 EGG01451.1 - 0.1 12.0 0.1 0.21 11.0 0.0 1.5 1 1 1 2 2 2 0 Bacterial TniB protein NIF PF03031.18 EGG01452.1 - 2e-49 167.3 0.1 2.3e-49 167.2 0.1 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 EGG01452.1 - 0.00075 20.0 0.2 0.0092 16.4 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.32 EGG01453.1 - 0.0013 19.5 1.9 2.2 9.3 0.3 4.4 4 1 0 4 4 4 2 WD domain, G-beta repeat Ribonucleas_3_2 PF11469.8 EGG01455.1 - 0.015 15.7 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease III DUF4858 PF16150.5 EGG01455.1 - 0.16 12.0 0.1 0.18 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4858) Glyco_hydro_10 PF00331.20 EGG01456.1 - 2.8e-98 328.9 0.0 3.5e-98 328.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Pkinase PF00069.25 EGG01457.1 - 8.6e-45 153.1 0.0 3.9e-44 151.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG01457.1 - 3.3e-23 82.3 0.1 8.8e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGG01457.1 - 2.1e-05 24.0 0.1 0.06 12.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 EGG01457.1 - 0.0038 16.2 0.0 0.0072 15.3 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGG01457.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGG01457.1 - 0.012 15.5 0.1 0.21 11.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG01457.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGG01457.1 - 0.059 13.0 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family MFS_1 PF07690.16 EGG01458.1 - 3.2e-10 39.5 33.2 3.9e-09 35.9 16.1 3.0 2 2 1 3 3 3 2 Major Facilitator Superfamily DUF1145 PF06611.12 EGG01458.1 - 0.017 15.1 0.4 4 7.5 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) Pterin_4a PF01329.19 EGG01459.1 - 6.2e-17 61.6 0.0 8.1e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DUF3855 PF12967.7 EGG01467.1 - 0.058 13.4 0.2 0.13 12.3 0.1 1.6 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3855) SRF-TF PF00319.18 EGG01469.1 - 6.1e-18 64.0 0.1 6.1e-18 64.0 0.1 2.0 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GTSE1_N PF15259.6 EGG01469.1 - 0.059 13.6 0.2 0.084 13.1 0.2 1.2 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 SKA1 PF07160.12 EGG01470.1 - 0.04 13.8 0.1 0.049 13.5 0.1 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Mur_ligase_M PF08245.12 EGG01471.1 - 5.6e-06 26.5 0.0 1.4e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Pho88 PF10032.9 EGG01472.1 - 2.4e-72 242.0 0.5 2.7e-72 241.9 0.5 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ribonuclease_T2 PF00445.18 EGG01473.1 - 1.7e-36 126.2 2.6 2.5e-36 125.6 2.6 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Glyco_hydro_7 PF00840.20 EGG01475.1 - 2.9e-201 668.8 9.9 3.3e-201 668.7 9.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fer4_10 PF13237.6 EGG01475.1 - 1.6 8.9 7.0 24 5.1 0.0 3.3 3 0 0 3 3 3 0 4Fe-4S dicluster domain LPD39 PF18858.1 EGG01480.1 - 0.12 12.4 0.0 0.91 9.6 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 39 PAP2 PF01569.21 EGG01481.1 - 1.3e-32 112.4 1.2 2.7e-32 111.4 1.2 1.6 1 0 0 1 1 1 1 PAP2 superfamily DUF2339 PF10101.9 EGG01481.1 - 0.0054 15.4 3.5 0.0069 15.0 1.4 1.6 1 1 0 2 2 2 1 Predicted membrane protein (DUF2339) PAP2_3 PF14378.6 EGG01481.1 - 0.007 16.1 1.8 0.037 13.7 1.8 2.0 1 1 0 1 1 1 1 PAP2 superfamily EPL1 PF10513.9 EGG01483.1 - 6.5e-27 94.9 0.1 1.4e-26 93.7 0.1 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like FANCI_S1 PF14675.6 EGG01484.1 - 0.17 11.4 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 1 Cadherin_C_2 PF16492.5 EGG01485.1 - 0.12 13.2 1.2 0.15 12.8 1.2 1.3 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal ING PF12998.7 EGG01486.1 - 7.1e-11 42.6 0.0 2.7e-10 40.7 0.0 2.1 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGG01486.1 - 2.5e-06 27.3 7.4 4.7e-06 26.4 7.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGG01486.1 - 0.0019 17.7 1.6 0.0036 16.8 1.6 1.5 1 0 0 1 1 1 1 PHD-finger CFEM PF05730.11 EGG01486.1 - 0.061 13.4 0.6 0.13 12.3 0.6 1.5 1 0 0 1 1 1 0 CFEM domain F-box-like PF12937.7 EGG01487.1 - 0.0013 18.6 0.1 0.0079 16.1 0.0 2.4 2 1 0 2 2 2 1 F-box-like Retrotran_gag_2 PF14223.6 EGG01487.1 - 0.0016 18.2 0.0 0.0037 16.9 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type F-box PF00646.33 EGG01487.1 - 0.011 15.6 0.1 4.4 7.3 0.0 2.9 2 0 0 2 2 2 0 F-box domain Complex1_LYR PF05347.15 EGG01488.1 - 9.2e-08 32.0 4.8 1e-07 31.9 0.7 2.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF4606 PF15379.6 EGG01488.1 - 0.21 11.9 3.9 0.54 10.5 0.2 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4606) DUF5100 PF17029.5 EGG01488.1 - 3.4 7.5 9.2 1.1 9.2 1.3 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5100) ALMT PF11744.8 EGG01488.1 - 3.7 6.3 5.3 0.69 8.7 1.1 1.8 2 0 0 2 2 2 0 Aluminium activated malate transporter CDC73_C PF05179.14 EGG01489.1 - 7e-40 136.3 0.8 1.4e-39 135.3 0.6 1.7 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 EGG01489.1 - 0.00012 21.6 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal Pkinase PF00069.25 EGG01491.1 - 4.6e-05 22.9 0.0 5.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain GldH_lipo PF14109.6 EGG01491.1 - 0.037 14.8 0.2 0.058 14.2 0.2 1.3 1 0 0 1 1 1 0 GldH lipoprotein Nicastrin PF05450.15 EGG01492.1 - 0.044 13.3 1.0 0.057 12.9 1.0 1.3 1 0 0 1 1 1 0 Nicastrin Kelch_4 PF13418.6 EGG01494.1 - 7.2e-10 38.7 2.1 4.2e-05 23.5 0.0 3.7 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EGG01494.1 - 9e-10 38.1 0.3 0.0012 18.7 0.0 4.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 EGG01494.1 - 2.8e-09 36.9 0.5 0.12 12.7 0.0 4.9 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 EGG01494.1 - 3.7e-08 33.2 3.4 0.00035 20.5 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 EGG01494.1 - 9.3e-08 31.5 0.0 0.0031 17.1 0.0 3.1 2 1 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 EGG01494.1 - 3.1e-06 27.3 11.9 0.0022 18.3 0.0 5.7 6 0 0 6 6 6 2 Galactose oxidase, central domain BTB PF00651.31 EGG01494.1 - 0.019 15.2 0.1 3.4 7.9 0.1 2.4 2 0 0 2 2 2 0 BTB/POZ domain Nuc_sug_transp PF04142.15 EGG01495.1 - 4.5e-86 288.9 11.1 5.3e-86 288.6 11.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EGG01495.1 - 4.6e-09 35.9 12.8 8.5e-09 35.0 12.8 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGG01495.1 - 0.00011 22.4 30.3 0.023 14.9 9.2 2.7 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 EGG01495.1 - 0.0091 15.6 0.7 0.0091 15.6 0.7 2.6 2 1 0 2 2 2 1 Putative multidrug resistance efflux transporter AlaDh_PNT_N PF05222.15 EGG01496.1 - 6.1e-27 94.6 0.0 8.5e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EGG01496.1 - 0.0052 16.1 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TPK_catalytic PF04263.16 EGG01497.1 - 4.8e-35 120.2 0.1 8.7e-34 116.2 0.0 2.1 1 1 0 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EGG01497.1 - 2.5e-16 59.1 0.4 4.2e-16 58.4 0.4 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain AA_permease_2 PF13520.6 EGG01499.1 - 0.26 10.1 0.0 0.36 9.6 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease UDG PF03167.19 EGG01501.1 - 1.4e-17 64.1 0.0 1e-09 38.6 0.0 2.2 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily Clr5 PF14420.6 EGG01502.1 - 1.3e-05 25.3 0.0 0.14 12.4 0.0 2.7 3 0 0 3 3 3 2 Clr5 domain HTH_21 PF13276.6 EGG01502.1 - 0.11 12.7 0.1 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 HTH-like domain DUF604 PF04646.12 EGG01503.1 - 4.9e-13 49.1 0.0 1.7e-12 47.3 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 EGG01503.1 - 3.6e-07 29.9 0.0 6.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Fringe-like FAR1 PF03101.15 EGG01504.1 - 0.074 13.8 0.5 0.074 13.8 0.5 2.6 2 1 0 2 2 2 0 FAR1 DNA-binding domain CxC1 PF18802.1 EGG01505.1 - 1e-29 102.8 0.0 1.7e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG01505.1 - 5.2e-06 26.6 0.0 9.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Cofac_haem_bdg PF04187.13 EGG01505.1 - 0.056 13.4 0.0 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN NAD_binding_8 PF13450.6 EGG01506.1 - 1.5e-12 47.6 0.0 2.7e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGG01506.1 - 2.8e-07 30.2 0.0 2.8e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EGG01506.1 - 0.00037 20.2 0.1 0.00054 19.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG01506.1 - 0.0086 15.3 0.0 0.0098 15.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG01506.1 - 0.023 14.7 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EGG01506.1 - 0.094 11.4 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EGG01506.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EGG01506.1 - 0.2 10.9 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_47 PF01532.20 EGG01508.1 - 3.9e-151 504.0 0.0 5.1e-151 503.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Abhydro_lipase PF04083.16 EGG01509.1 - 0.18 11.4 0.0 0.49 10.0 0.0 1.7 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF3682 PF12446.8 EGG01509.1 - 0.28 11.6 5.7 0.46 11.0 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) MAGI_u1 PF16663.5 EGG01509.1 - 8.5 6.5 0.0 8.5 6.5 0.0 3.6 4 1 0 4 4 4 0 Unstructured region on MAGI CTD PF12815.7 EGG01512.1 - 0.21 12.2 13.3 5.5 7.6 13.2 2.9 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 PRR20 PF15708.5 EGG01512.1 - 0.56 10.1 12.8 1.5 8.6 1.9 2.8 1 1 2 3 3 3 0 Proline-rich protein family 20 Ydr279_N PF17745.1 EGG01512.1 - 1.2 9.5 5.5 0.8 10.0 0.3 2.8 2 1 0 2 2 2 0 Ydr279p protein triple barrel domain RNA_pol_3_Rpc31 PF11705.8 EGG01513.1 - 0.23 11.7 21.8 0.2 11.9 19.8 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 EGG01513.1 - 0.49 8.6 13.5 0.64 8.2 13.5 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EGG01513.1 - 3.7 6.8 18.1 5.7 6.2 18.1 1.2 1 0 0 1 1 1 0 BUD22 Astro_capsid_p PF12226.8 EGG01513.1 - 5.5 6.0 17.3 8.8 5.4 17.3 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RRN3 PF05327.11 EGG01513.1 - 6.1 5.3 11.5 9.3 4.7 11.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CxC5 PF18718.1 EGG01514.1 - 1.1e-28 99.7 7.7 2.4e-28 98.6 7.7 1.6 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG01514.1 - 5.8e-19 68.1 0.5 5.8e-19 68.1 0.5 2.6 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases Gly_transf_sug PF04488.15 EGG01515.1 - 9.3e-07 29.4 0.4 6.7e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EGG01515.1 - 0.00043 19.7 0.2 0.0022 17.4 0.0 2.1 1 1 1 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Dehydrin PF00257.19 EGG01515.1 - 1.4 9.4 5.6 3.2 8.3 5.6 1.6 1 0 0 1 1 1 0 Dehydrin Atg8 PF02991.16 EGG01516.1 - 2.5e-52 175.4 0.1 2.9e-52 175.2 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EGG01516.1 - 9.6e-07 29.1 0.0 1.2e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF1892 PF08987.10 EGG01519.1 - 0.071 13.3 0.0 0.095 12.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1892) Thiolase_N PF00108.23 EGG01522.1 - 1.7e-76 257.1 7.1 1.8e-76 257.0 5.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGG01522.1 - 2.1e-40 137.2 0.1 6.3e-40 135.7 0.1 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGG01522.1 - 0.0012 18.5 1.5 0.0012 18.5 1.5 2.8 4 0 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain FAR1 PF03101.15 EGG01525.1 - 2.4e-06 28.1 0.7 6.8e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.11 EGG01525.1 - 0.0012 19.2 0.1 0.0012 19.2 0.1 2.8 3 0 0 3 3 3 1 Transcription factor AFT HP0268 PF18618.1 EGG01528.1 - 0.16 12.5 0.1 0.34 11.4 0.1 1.5 1 0 0 1 1 1 0 HP0268 PH_3 PF14593.6 EGG01529.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 PH domain OTU PF02338.19 EGG01530.1 - 1.8e-10 41.4 0.0 2.6e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGG01530.1 - 0.038 13.5 0.0 0.23 10.9 0.0 2.1 2 1 0 2 2 2 0 Peptidase C65 Otubain Ery_res_leader1 PF08051.11 EGG01530.1 - 0.17 12.1 0.0 0.74 10.1 0.0 2.1 1 0 0 1 1 1 0 Erythromycin resistance leader peptide OTU PF02338.19 EGG01531.1 - 5.5e-17 62.4 0.0 8.3e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGG01531.1 - 0.00016 21.2 0.1 0.15 11.5 0.0 2.2 1 1 0 2 2 2 2 Peptidase C65 Otubain PIG-P PF08510.12 EGG01532.1 - 1.6e-24 86.2 1.6 2e-24 85.8 1.6 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EGG01532.1 - 0.00017 21.9 5.1 0.00026 21.2 5.1 1.3 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DPM3 PF08285.11 EGG01532.1 - 0.13 12.5 1.0 0.18 12.0 1.0 1.3 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Flu_NS1 PF00600.19 EGG01532.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) OTU PF02338.19 EGG01533.1 - 5.4e-20 72.2 0.0 1.5e-10 41.6 0.0 2.4 2 0 0 2 2 2 2 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGG01533.1 - 1.3e-05 24.8 0.0 0.22 10.9 0.0 3.1 3 0 0 3 3 3 2 Peptidase C65 Otubain DUF3234 PF11572.8 EGG01533.1 - 0.21 11.8 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3234) OTU PF02338.19 EGG01534.1 - 3.6e-11 43.6 0.1 1.6e-10 41.6 0.1 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGG01534.1 - 0.00014 21.4 2.2 0.0092 15.5 1.7 2.1 2 0 0 2 2 2 2 Peptidase C65 Otubain OTU PF02338.19 EGG01535.1 - 1.2e-10 41.9 0.0 2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGG01535.1 - 0.00012 21.7 2.2 0.0019 17.7 0.3 2.1 1 1 1 2 2 2 2 Peptidase C65 Otubain RCC_reductase PF06405.11 EGG01536.1 - 0.16 11.1 2.1 0.1 11.7 0.3 1.5 2 0 0 2 2 2 0 Red chlorophyll catabolite reductase (RCC reductase) Mem_trans PF03547.18 EGG01537.1 - 1.1e-38 132.7 0.0 6e-38 130.2 0.0 2.1 1 1 0 1 1 1 1 Membrane transport protein His_Phos_2 PF00328.22 EGG01538.1 - 1.9e-39 136.1 0.0 3.1e-39 135.4 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NOA36 PF06524.12 EGG01540.1 - 6.5 6.0 12.7 7.6 5.8 12.7 1.2 1 0 0 1 1 1 0 NOA36 protein Septin PF00735.18 EGG01545.1 - 6.2e-22 78.2 1.2 6.2e-22 78.2 1.2 2.4 2 1 0 2 2 2 1 Septin DUF2833 PF11090.8 EGG01545.1 - 0.064 13.7 0.4 12 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) DUF1319 PF07028.11 EGG01545.1 - 0.74 10.1 5.7 1.9 8.8 5.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) GCM PF03615.15 EGG01552.1 - 0.036 13.9 1.4 0.1 12.5 1.4 1.7 1 1 0 1 1 1 0 GCM motif protein BSP PF04450.12 EGG01552.1 - 0.11 12.2 0.0 3.1 7.5 0.0 2.8 3 0 0 3 3 3 0 Peptidase of plants and bacteria YjeJ PF15922.5 EGG01553.1 - 3.2 6.9 4.6 1.2 8.3 2.5 1.3 2 0 0 2 2 2 0 YjeJ-like LIM PF00412.22 EGG01555.1 - 3.9e-29 100.6 29.6 1.8e-12 47.3 5.7 4.8 4 1 0 4 4 4 4 LIM domain DUF2321 PF10083.9 EGG01555.1 - 4.3 6.9 11.9 0.56 9.8 0.6 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) COX4 PF02936.14 EGG01559.1 - 4.5e-35 120.7 0.1 5.9e-35 120.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1289 PF06945.13 EGG01559.1 - 2.7 7.9 4.9 4.6 7.1 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1289) NMT1 PF09084.11 EGG01561.1 - 3e-72 243.1 0.0 3.9e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EGG01561.1 - 0.088 12.5 0.0 0.98 9.1 0.0 2.3 2 1 0 3 3 3 0 NMT1-like family WD40 PF00400.32 EGG01562.1 - 0.0014 19.4 0.0 0.003 18.3 0.0 1.6 1 1 0 1 1 1 1 WD domain, G-beta repeat EF-hand_4 PF12763.7 EGG01563.1 - 1.2e-41 140.8 0.0 2.5e-17 62.7 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 EGG01563.1 - 5.1e-08 32.7 0.0 1.3e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.6 EGG01563.1 - 1.4e-06 28.6 0.0 0.012 16.1 0.0 3.9 4 0 0 4 4 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EGG01563.1 - 1.5e-05 24.2 0.0 0.24 11.0 0.0 3.9 4 0 0 4 4 3 2 EF hand EF-hand_6 PF13405.6 EGG01563.1 - 0.00025 20.8 0.1 5.7 7.1 0.0 4.1 3 0 0 3 3 3 1 EF-hand domain FUSC PF04632.12 EGG01563.1 - 0.0067 15.0 4.9 0.011 14.3 4.9 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein family ATG16 PF08614.11 EGG01563.1 - 0.012 15.8 10.6 0.012 15.8 10.6 2.9 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 EGG01563.1 - 0.024 14.7 12.6 1.9 8.5 0.0 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Vps51 PF08700.11 EGG01563.1 - 0.06 13.4 11.0 1.2 9.3 1.2 2.9 1 1 1 2 2 2 0 Vps51/Vps67 UBA_3 PF09288.10 EGG01563.1 - 0.085 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain DUF2730 PF10805.8 EGG01563.1 - 0.1 12.7 9.7 3.2 7.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF745 PF05335.13 EGG01563.1 - 0.13 12.0 11.5 0.41 10.3 11.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF745) SAM_KSR1 PF13543.6 EGG01563.1 - 0.14 12.3 8.4 0.27 11.4 8.4 1.5 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 NPV_P10 PF05531.12 EGG01563.1 - 0.33 11.4 5.0 9.5 6.8 0.6 3.2 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein FPP PF05911.11 EGG01563.1 - 0.35 9.0 17.7 1.3 7.1 13.7 1.8 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Exonuc_VII_L PF02601.15 EGG01563.1 - 0.38 10.3 10.9 0.65 9.5 10.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 EGG01563.1 - 0.46 9.3 19.4 2 7.2 0.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EGG01563.1 - 0.52 10.4 21.4 0.18 11.9 16.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Tup_N PF08581.10 EGG01563.1 - 0.61 10.4 7.7 1.1 9.6 4.9 2.3 1 1 1 2 2 2 0 Tup N-terminal ADIP PF11559.8 EGG01563.1 - 0.73 9.9 22.4 0.3 11.2 7.1 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.11 EGG01563.1 - 1.8 7.3 20.4 2.7 6.7 20.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like SPAM PF02090.15 EGG01563.1 - 2.3 8.1 13.3 0.9 9.3 5.2 2.3 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein DUF812 PF05667.11 EGG01563.1 - 2.4 7.0 19.7 8.3 5.2 19.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) CENP-Q PF13094.6 EGG01563.1 - 2.7 8.1 19.5 13 5.9 17.2 2.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Phage_GP20 PF06810.11 EGG01563.1 - 3.5 7.4 18.5 5.2 6.9 8.1 3.5 2 1 2 4 4 3 0 Phage minor structural protein GP20 Fez1 PF06818.15 EGG01563.1 - 4.8 7.6 19.1 12 6.3 6.6 2.0 1 1 1 2 2 2 0 Fez1 V_ATPase_I PF01496.19 EGG01563.1 - 5.4 4.8 5.6 9.4 4.0 5.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4472 PF14739.6 EGG01563.1 - 8.2 7.2 15.6 12 6.7 11.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) SlyX PF04102.12 EGG01563.1 - 9 7.0 16.6 3.1 8.5 0.1 3.9 1 1 2 3 3 3 0 SlyX Val_tRNA-synt_C PF10458.9 EGG01563.1 - 9.7 6.6 10.7 3.2 8.1 0.3 3.0 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm ATG_C PF09333.11 EGG01564.1 - 1e-28 99.5 0.1 5.6e-28 97.1 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EGG01564.1 - 0.00027 20.8 0.1 0.00098 18.9 0.0 2.0 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal ATG2_CAD PF13329.6 EGG01564.1 - 0.00062 19.5 0.1 0.0068 16.1 0.0 2.8 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.7 EGG01564.1 - 0.00089 19.4 0.0 0.0029 17.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Prefoldin PF02996.17 EGG01564.1 - 0.5 10.3 3.1 1.9 8.4 1.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit SUZ PF12752.7 EGG01565.1 - 4.5e-10 40.1 3.0 4.5e-10 40.1 3.0 6.2 7 1 0 7 7 7 1 SUZ domain R3H PF01424.22 EGG01565.1 - 0.037 14.0 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 R3H domain MDM10 PF12519.8 EGG01566.1 - 2.3e-72 244.4 7.4 8.3e-70 235.9 7.4 2.4 1 1 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 EGG01566.1 - 0.0084 15.6 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic porin PuR_N PF09182.10 EGG01566.1 - 0.026 14.5 0.5 1.8 8.5 0.2 2.7 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal Pkinase PF00069.25 EGG01567.1 - 7.5e-73 245.1 0.0 8.4e-73 245.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG01567.1 - 1.5e-31 109.7 0.0 1.9e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG01567.1 - 8.2e-05 22.1 0.0 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGG01567.1 - 0.00035 19.6 0.1 0.011 14.7 0.0 2.2 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGG01567.1 - 0.0044 17.0 0.0 0.011 15.7 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGG01567.1 - 0.017 14.2 0.1 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FA_hydroxylase PF04116.13 EGG01568.1 - 6.1e-22 78.4 19.9 6.1e-22 78.4 19.9 2.7 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DSPc PF00782.20 EGG01571.1 - 2e-26 92.4 0.0 3.3e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG01571.1 - 0.0048 16.5 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGG01571.1 - 0.071 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate RPN13_C PF16550.5 EGG01572.1 - 3.9e-21 75.3 0.0 6.7e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 EGG01572.1 - 6.7e-21 74.6 0.0 9.9e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Pox_Ag35 PF03286.14 EGG01573.1 - 6 6.6 7.7 1.1 9.0 3.8 1.7 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Keratin_2_head PF16208.5 EGG01576.1 - 8.8 6.4 39.6 3.5e+02 1.2 39.6 2.0 1 1 0 1 1 1 0 Keratin type II head CUB_2 PF02408.20 EGG01580.1 - 0.0054 16.5 0.7 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 CUB-like domain Chs7 PF12271.8 EGG01583.1 - 1.8e-30 106.3 5.1 2.1e-30 106.1 5.1 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone PRIMA1 PF16101.5 EGG01583.1 - 0.03 14.4 0.4 0.045 13.8 0.4 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 UPF0182 PF03699.13 EGG01583.1 - 0.39 8.8 1.3 0.45 8.6 1.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) ABC_membrane_2 PF06472.15 EGG01584.1 - 2.6e-90 302.5 3.4 3.6e-90 302.0 3.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGG01584.1 - 2.9e-18 66.7 0.0 6.1e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGG01584.1 - 7.7e-05 22.6 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGG01584.1 - 0.00029 21.4 1.4 0.014 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGG01584.1 - 0.019 14.9 0.0 0.062 13.2 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 EGG01584.1 - 0.027 14.2 0.2 0.078 12.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain SMC_N PF02463.19 EGG01584.1 - 0.034 13.6 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 EGG01584.1 - 0.092 12.3 0.0 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 EGG01584.1 - 0.15 11.1 0.0 5 6.2 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain Mcl1_mid PF12341.8 EGG01585.1 - 1.2e-89 300.6 0.1 3.5e-88 295.8 0.0 2.7 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EGG01585.1 - 4.9e-19 68.3 10.5 1.6e-05 25.6 0.2 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG01585.1 - 5.6e-10 39.4 0.2 0.003 17.8 0.1 4.4 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 EGG01585.1 - 0.0096 15.0 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain RAB3GAP2_N PF14655.6 EGG01585.1 - 0.059 12.6 0.0 3.6 6.7 0.1 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nbas_N PF15492.6 EGG01585.1 - 0.089 12.1 0.2 0.86 8.9 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Poxvirus PF06227.12 EGG01586.1 - 0.056 13.2 0.4 0.086 12.6 0.4 1.2 1 0 0 1 1 1 0 dsDNA Poxvirus PRANC PF09372.10 EGG01586.1 - 0.11 12.8 0.2 0.25 11.7 0.2 1.5 1 0 0 1 1 1 0 PRANC domain Ammonium_transp PF00909.21 EGG01588.1 - 2.6e-96 322.8 30.5 3e-96 322.6 30.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family ORC3_N PF07034.11 EGG01590.1 - 2.3e-29 102.5 5.4 2.4e-28 99.2 5.4 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 EGG01590.1 - 2.1e-13 50.5 0.0 8.6e-12 45.3 0.0 2.3 1 1 0 1 1 1 1 Origin recognition complex winged helix C-terminal Ammonium_transp PF00909.21 EGG01591.1 - 4.4e-101 338.5 26.7 5e-101 338.3 26.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family RTX PF02382.15 EGG01591.1 - 0.27 10.9 0.6 0.53 9.9 0.6 1.4 1 0 0 1 1 1 0 N-terminal domain in RTX protein DUF2953 PF11167.8 EGG01591.1 - 8.2 6.6 11.6 15 5.7 0.4 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2953) GP38 PF05268.11 EGG01594.1 - 0.0033 17.1 0.8 0.0049 16.5 0.8 1.2 1 0 0 1 1 1 1 Phage tail fibre adhesin Gp38 SDA1 PF05285.12 EGG01596.1 - 0.75 9.2 22.2 0.82 9.0 22.2 1.0 1 0 0 1 1 1 0 SDA1 FadA PF09403.10 EGG01598.1 - 3.3 8.2 12.2 0.33 11.5 5.7 2.4 2 1 0 2 2 2 0 Adhesion protein FadA Radical_SAM_C PF16199.5 EGG01599.1 - 1.9e-31 107.9 0.0 5.8e-31 106.4 0.0 1.9 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EGG01599.1 - 2.3e-17 63.9 0.0 5.9e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EGG01599.1 - 1.3e-09 38.3 0.1 2.3e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG01599.1 - 2e-05 24.5 0.0 4.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG01599.1 - 0.0078 16.6 0.1 0.017 15.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG01599.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein SLBP_RNA_bind PF15247.6 EGG01601.1 - 0.11 12.7 1.2 0.85 9.8 0.1 2.7 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain CxC1 PF18802.1 EGG01602.1 - 3.9e-25 88.0 2.2 3.9e-25 88.0 2.2 1.7 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG01602.1 - 3.9e-08 33.4 0.9 7.3e-08 32.5 0.9 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Imm10 PF15588.6 EGG01604.1 - 0.064 13.4 0.0 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Immunity protein 10 DcpS_C PF11969.8 EGG01605.1 - 7.8e-27 94.0 0.3 1.8e-26 92.8 0.3 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Alpha_kinase PF02816.18 EGG01608.1 - 5.5e-21 75.5 0.7 7.7e-21 75.1 0.7 1.2 1 0 0 1 1 1 1 Alpha-kinase family zf-C3HC4 PF00097.25 EGG01609.1 - 0.035 14.0 3.1 0.11 12.4 3.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF600 PF04634.12 EGG01609.1 - 0.094 12.8 0.1 0.64 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF600 zf-4CXXC_R1 PF10497.9 EGG01609.1 - 0.15 12.3 3.8 0.23 11.7 3.8 1.2 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_2 PF13639.6 EGG01609.1 - 1.2 9.5 5.8 1.9 8.9 5.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_2 PF13639.6 EGG01613.1 - 9.4e-06 25.9 7.2 1.4e-05 25.4 7.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 EGG01613.1 - 0.00011 21.9 8.4 0.00019 21.2 8.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EGG01613.1 - 0.00047 20.0 7.1 0.00085 19.1 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG01613.1 - 0.0041 17.0 7.4 0.0065 16.3 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 EGG01613.1 - 0.063 13.2 4.6 0.12 12.3 4.6 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.6 EGG01613.1 - 0.07 13.0 7.3 0.11 12.3 7.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG01613.1 - 0.23 11.4 3.6 0.48 10.3 3.6 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGG01613.1 - 4 7.5 8.1 7.4 6.6 8.1 1.5 1 1 0 1 1 1 0 zinc-RING finger domain Pyr_redox_2 PF07992.14 EGG01614.1 - 6.9e-41 140.4 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG01614.1 - 5.4e-13 49.3 0.2 1.2e-09 38.5 0.0 3.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EGG01614.1 - 1.2e-10 40.2 5.1 4.3e-06 25.9 0.6 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGG01614.1 - 1.3e-08 34.0 5.4 0.00041 20.1 0.1 3.0 3 0 0 3 3 2 2 EF-hand domain EF-hand_7 PF13499.6 EGG01614.1 - 2.1e-08 34.5 1.1 0.0015 18.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG01614.1 - 1.3e-07 30.8 3.1 0.00015 21.1 0.4 2.5 2 0 0 2 2 2 2 EF hand Pyr_redox_3 PF13738.6 EGG01614.1 - 8.5e-06 25.2 4.0 0.00084 18.7 0.4 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.6 EGG01614.1 - 0.0015 18.4 4.7 0.0047 16.7 3.8 2.3 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGG01614.1 - 0.0018 18.6 1.8 0.59 10.5 0.1 2.8 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGG01614.1 - 0.017 15.1 1.2 0.6 10.1 0.2 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EGG01614.1 - 0.07 13.1 0.9 0.51 10.3 0.2 2.5 1 1 2 3 3 3 0 Caleosin related protein REF PF05755.12 EGG01614.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Peptidase_C54 PF03416.19 EGG01617.1 - 7.5e-14 51.8 0.0 8.7e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 MLD PF11647.8 EGG01617.1 - 0.094 13.0 2.1 0.13 12.6 1.4 1.6 2 0 0 2 2 2 0 Membrane Localization Domain Dynactin PF12455.8 EGG01620.1 - 0.0037 16.5 0.0 0.0049 16.1 0.0 1.3 1 1 0 1 1 1 1 Dynein associated protein zf-UBR PF02207.20 EGG01621.1 - 9.2 6.5 9.5 4.9 7.4 2.0 3.1 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) Npun_R1517 PF18068.1 EGG01623.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Npun R1517 DUF3537 PF12056.8 EGG01623.1 - 0.079 11.8 0.3 0.14 11.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) T6SS_HCP PF05638.12 EGG01623.1 - 6 7.3 7.5 1.5 9.2 3.1 2.1 2 0 0 2 2 2 0 Type VI secretion system effector, Hcp AhpC-TSA_2 PF13911.6 EGG01625.1 - 6.4e-17 61.7 0.0 9.2e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGG01625.1 - 3e-05 23.9 0.0 4.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGG01625.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Redoxin AhpC-TSA_2 PF13911.6 EGG01626.1 - 1.4e-13 51.0 0.1 6.1e-07 29.6 0.0 2.2 1 1 1 2 2 2 2 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGG01626.1 - 1e-05 25.4 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 EGG01628.1 - 4e-17 62.4 0.0 5.8e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGG01628.1 - 1.4e-05 25.0 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family zinc_ribbon_15 PF17032.5 EGG01629.1 - 2.1e-06 28.4 1.1 3.8e-06 27.6 1.1 1.5 1 0 0 1 1 1 1 zinc-ribbon family RecR PF02132.15 EGG01629.1 - 0.032 13.8 2.4 0.48 10.0 0.4 2.2 2 0 0 2 2 2 0 RecR protein zinc_ribbon_9 PF14369.6 EGG01629.1 - 0.039 14.2 1.9 0.062 13.6 0.7 1.9 2 0 0 2 2 2 0 zinc-ribbon Zn_Tnp_IS1595 PF12760.7 EGG01629.1 - 0.3 11.1 6.4 0.94 9.5 6.4 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain FYVE_2 PF02318.16 EGG01629.1 - 0.44 10.8 6.2 1.7 8.9 6.2 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger Glyco_hydro_47 PF01532.20 EGG01630.1 - 0.00013 21.0 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.20 EGG01631.1 - 8.5e-123 410.6 0.0 9.8e-123 410.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rep_Org_C PF06926.11 EGG01636.1 - 0.026 14.8 0.8 0.05 13.9 0.5 1.7 1 1 0 1 1 1 0 Putative replisome organiser protein C-terminus GAS PF13851.6 EGG01638.1 - 0.0036 16.7 5.0 0.0062 15.9 5.0 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 EGG01638.1 - 0.017 15.2 0.3 0.032 14.3 0.3 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 EGG01638.1 - 0.038 13.8 1.1 4.7 7.1 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 NPV_P10 PF05531.12 EGG01638.1 - 0.042 14.3 2.9 0.21 12.1 0.3 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MT PF12777.7 EGG01638.1 - 0.064 12.3 0.4 0.096 11.7 0.4 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor BLOC1_2 PF10046.9 EGG01638.1 - 0.22 11.8 3.2 2.9 8.3 0.2 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCM2_C PF16545.5 EGG01638.1 - 0.26 11.8 1.9 2.1 8.9 0.4 2.2 1 1 1 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology Shugoshin_N PF07558.11 EGG01638.1 - 0.26 11.2 1.8 15 5.6 0.1 2.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Med10 PF09748.9 EGG01638.1 - 0.65 10.0 5.0 0.7 9.9 1.2 2.7 2 1 1 3 3 3 0 Transcription factor subunit Med10 of Mediator complex FlaC_arch PF05377.11 EGG01638.1 - 0.76 10.2 6.5 4.4 7.8 0.4 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 EGG01638.1 - 0.94 10.1 7.6 15 6.3 2.6 2.7 1 1 0 2 2 2 0 SlyX ASF1_hist_chap PF04729.13 EGG01640.1 - 1e-69 233.4 0.1 1.6e-69 232.8 0.1 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone Dor1 PF04124.12 EGG01644.1 - 1.6e-12 46.8 3.1 1.8e-05 23.6 0.0 3.8 3 2 0 3 3 3 2 Dor1-like family Metallophos PF00149.28 EGG01645.1 - 1.6e-33 117.0 0.1 2.2e-33 116.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EGG01645.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 EGG01645.1 - 0.02 15.3 0.1 0.052 14.0 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain RNA_polI_A14 PF08203.11 EGG01646.1 - 0.14 12.8 1.1 0.58 10.9 1.1 2.1 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Spc29 PF17082.5 EGG01649.1 - 0.0084 16.0 1.2 0.016 15.1 1.2 1.5 1 0 0 1 1 1 1 Spindle Pole Component 29 ALIX_LYPXL_bnd PF13949.6 EGG01649.1 - 0.41 9.9 6.3 0.73 9.1 6.3 1.4 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV PRIMA1 PF16101.5 EGG01654.1 - 0.015 15.3 0.0 0.015 15.3 0.0 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Ras PF00071.22 EGG01654.1 - 0.054 13.1 0.1 0.078 12.6 0.1 1.3 1 0 0 1 1 1 0 Ras family DUF5434 PF17502.2 EGG01657.1 - 0.011 15.8 0.7 0.016 15.2 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5434) Uricase PF01014.18 EGG01660.1 - 5.9e-56 188.3 0.1 1.3e-30 106.3 0.0 2.0 2 0 0 2 2 2 2 Uricase TOBE PF03459.17 EGG01660.1 - 0.048 13.9 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 TOBE domain Ribosomal_L18A PF01775.17 EGG01662.1 - 2.5e-56 189.0 0.4 3.1e-56 188.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PE PF00934.20 EGG01663.1 - 0.091 13.1 0.6 0.24 11.7 0.6 1.7 1 0 0 1 1 1 0 PE family SKA1 PF07160.12 EGG01663.1 - 0.27 11.1 7.0 0.13 12.1 4.0 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Macoilin PF09726.9 EGG01663.1 - 0.29 9.6 4.6 0.52 8.8 4.6 1.4 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 EGG01663.1 - 1.6 7.4 4.5 0.46 9.2 1.2 1.8 2 0 0 2 2 2 0 Presenilin ASD2 PF08687.11 EGG01663.1 - 2.1 7.9 6.5 0.97 8.9 3.7 1.8 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 RINGv PF12906.7 EGG01664.1 - 1.7e-05 24.9 4.5 0.00063 19.8 2.6 2.4 2 0 0 2 2 2 2 RING-variant domain Zn_ribbon_17 PF17120.5 EGG01664.1 - 0.55 9.9 4.0 0.11 12.1 0.4 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 EGG01664.1 - 5.2 7.5 7.1 1.8 8.9 2.5 2.3 2 0 0 2 2 2 0 Ring finger domain AFT PF08731.11 EGG01665.1 - 0.00025 21.4 0.0 0.00038 20.8 0.0 1.3 1 0 0 1 1 1 1 Transcription factor AFT FAR1 PF03101.15 EGG01665.1 - 0.0013 19.4 0.0 0.002 18.8 0.0 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain RRM_1 PF00076.22 EGG01666.1 - 1.3e-15 56.9 0.1 1.4e-09 37.6 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG01666.1 - 0.00024 20.7 0.0 0.0046 16.5 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 EGG01669.1 - 3e-45 154.7 0.0 4.3e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG01669.1 - 7.5e-28 97.5 0.0 9.7e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG01669.1 - 0.0036 16.6 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG01669.1 - 0.0053 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG01669.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGG01669.1 - 0.035 13.7 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EGG01669.1 - 0.068 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Acyltransferase PF01553.21 EGG01670.1 - 1.1e-12 47.8 0.0 2.6e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 EGG01671.1 - 8.5e-42 143.3 0.0 1.2e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG01671.1 - 5.7e-40 137.2 0.0 5.5e-28 97.9 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG01671.1 - 1.4e-05 24.3 0.0 2.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGG01671.1 - 0.0012 17.7 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGG01671.1 - 0.028 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MHYT PF03707.16 EGG01672.1 - 0.092 12.9 0.5 0.23 11.6 0.5 1.7 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat DUF2663 PF10864.8 EGG01674.1 - 0.0069 16.8 1.4 0.15 12.5 0.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2663) Spore_YabQ PF09578.10 EGG01674.1 - 0.01 16.0 4.5 0.01 16.0 4.5 2.6 3 0 0 3 3 3 0 Spore cortex protein YabQ (Spore_YabQ) Glyco_hydr_116N PF12215.8 EGG01674.1 - 0.085 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Ctr PF04145.15 EGG01674.1 - 0.092 13.4 0.0 0.23 12.1 0.0 1.7 1 0 0 1 1 1 0 Ctr copper transporter family MARVEL PF01284.23 EGG01674.1 - 9.4 6.3 11.9 1.1e+02 2.7 11.9 2.6 1 1 0 1 1 1 0 Membrane-associating domain Glyco_hydr_116N PF12215.8 EGG01675.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term MARVEL PF01284.23 EGG01675.1 - 0.11 12.5 10.1 0.54 10.3 10.1 2.1 1 1 0 1 1 1 0 Membrane-associating domain Glyco_hydr_116N PF12215.8 EGG01676.1 - 0.11 12.0 1.1 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF3488 PF11992.8 EGG01676.1 - 0.31 9.9 2.6 0.53 9.2 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Pkinase PF00069.25 EGG01679.1 - 3.6e-42 144.6 0.0 5.1e-22 78.5 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG01679.1 - 2.2e-19 69.7 0.0 1.9e-14 53.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 EGG01679.1 - 2.5e-11 43.2 0.1 4.3e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Pepdidase_M14_N PF18027.1 EGG01679.1 - 0.044 14.1 0.2 0.15 12.4 0.2 1.9 1 0 0 1 1 1 0 Cytosolic carboxypeptidase N-terminal domain DUF1856 PF08983.10 EGG01680.1 - 0.064 13.5 0.6 0.14 12.4 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1856) Vps53_N PF04100.12 EGG01680.1 - 0.096 11.6 0.5 0.13 11.2 0.5 1.2 1 1 0 1 1 1 0 Vps53-like, N-terminal Baculo_PEP_C PF04513.12 EGG01681.1 - 0.00084 19.4 0.2 0.029 14.4 0.0 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus SEO_N PF14576.6 EGG01681.1 - 0.086 12.0 0.2 0.11 11.6 0.2 1.1 1 0 0 1 1 1 0 Sieve element occlusion N-terminus CP12 PF02672.15 EGG01681.1 - 0.1 13.4 0.9 0.22 12.3 0.9 1.5 1 0 0 1 1 1 0 CP12 domain IQCJ-SCHIP1 PF15157.6 EGG01681.1 - 0.13 12.1 0.4 0.22 11.4 0.4 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif UBA_6 PF18039.1 EGG01681.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain PCI PF01399.27 EGG01686.1 - 1.2e-08 35.4 0.0 3.2e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 PCI domain Pkinase PF00069.25 EGG01687.1 - 7.9e-73 245.1 2.5 9.1e-73 244.9 0.3 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG01687.1 - 1.7e-51 175.0 0.3 1.7e-51 175.0 0.3 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 EGG01687.1 - 6e-23 81.0 0.0 1.7e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 EGG01687.1 - 2.3e-10 40.9 0.2 4.7e-10 39.9 0.2 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EGG01687.1 - 2e-06 27.3 0.0 4.8e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGG01687.1 - 2.1e-06 27.0 0.1 4.5e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGG01687.1 - 5e-06 25.5 0.0 1.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase PH_11 PF15413.6 EGG01687.1 - 0.0051 17.2 2.0 0.088 13.2 0.6 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain APH PF01636.23 EGG01687.1 - 0.012 15.6 0.3 0.048 13.6 0.4 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF572 PF04502.13 EGG01690.1 - 1e-64 219.3 0.0 1.2e-64 219.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Zn-ribbon_8 PF09723.10 EGG01690.1 - 0.061 13.4 1.5 0.093 12.9 0.3 1.9 2 0 0 2 2 2 0 Zinc ribbon domain Esterase_phd PF10503.9 EGG01690.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Bromo_TP PF07524.13 EGG01691.1 - 5.1e-09 36.0 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 EGG01691.1 - 0.0015 18.6 0.0 0.0039 17.3 0.0 1.7 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold SRP9-21 PF05486.12 EGG01692.1 - 2.3e-10 40.7 1.2 1.2e-08 35.2 1.2 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Peptidase_S49_N PF08496.10 EGG01694.1 - 4.4 7.3 10.2 6.2 6.9 0.6 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Glyco_transf_25 PF01755.17 EGG01695.1 - 3.5e-07 30.3 1.4 0.0032 17.4 0.3 3.3 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Ntox34 PF15606.6 EGG01696.1 - 4 7.6 5.2 15 5.8 0.9 2.8 3 0 0 3 3 3 0 Bacterial toxin 34 CWC25 PF12542.8 EGG01697.1 - 2.9e-25 89.1 0.9 2.9e-25 89.1 0.9 3.6 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EGG01697.1 - 2.9e-13 49.7 11.7 2.9e-13 49.7 11.7 5.0 4 3 2 6 6 6 2 N-terminal domain of CBF1 interacting co-repressor CIR DUF2263 PF10021.9 EGG01697.1 - 0.029 14.7 0.8 0.1 13.0 0.8 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2263) zf-H2C2_2 PF13465.6 EGG01698.1 - 4.4e-07 30.0 1.5 4.4e-07 30.0 1.5 2.4 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGG01698.1 - 6.8e-06 26.2 4.4 0.023 15.1 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG01698.1 - 0.0003 21.4 7.6 0.059 14.2 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-BED PF02892.15 EGG01698.1 - 0.012 15.7 2.4 1.8 8.7 0.5 2.6 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_jaz PF12171.8 EGG01698.1 - 0.036 14.4 2.2 7.9 6.9 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EGG01698.1 - 0.11 12.2 0.9 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 EGG01698.1 - 0.31 11.5 5.7 3 8.4 0.5 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Defensin_big PF14862.6 EGG01699.1 - 0.42 10.9 4.6 0.12 12.7 1.3 1.8 2 0 0 2 2 2 0 Big defensin Bap31 PF05529.12 EGG01700.1 - 6.2e-38 129.7 0.8 8.1e-38 129.3 0.8 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Tfb4 PF03850.14 EGG01701.1 - 3.6e-91 305.5 1.7 4.2e-91 305.2 1.7 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 UPF0029 PF01205.19 EGG01705.1 - 1.8e-27 95.8 0.0 3e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 BLI1 PF17324.2 EGG01706.1 - 0.43 11.3 0.0 0.43 11.3 0.0 2.4 3 0 0 3 3 3 0 BLOC-1 interactor 1 zf-B_box PF00643.24 EGG01707.1 - 0.031 14.4 7.2 0.16 12.2 0.6 2.2 2 0 0 2 2 2 0 B-box zinc finger WD40 PF00400.32 EGG01708.1 - 2.1e-26 91.7 12.2 6.5e-05 23.6 0.6 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG01708.1 - 1.1e-09 38.5 0.5 0.65 10.3 0.0 5.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG01708.1 - 1e-05 24.6 1.3 0.0011 18.1 0.1 3.1 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EGG01708.1 - 0.028 13.0 0.0 0.082 11.4 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain zf-H2C2_2 PF13465.6 EGG01709.1 - 0.00045 20.5 5.3 0.0046 17.3 1.4 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGG01709.1 - 0.00058 20.2 11.9 0.06 13.8 0.4 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG01709.1 - 0.00081 20.0 9.5 0.16 12.9 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HE PF16278.5 EGG01709.1 - 0.02 15.3 2.1 3.5 8.1 0.1 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 EGG01709.1 - 0.84 9.6 5.2 1.3 9.0 2.6 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF1158 PF06643.11 EGG01711.1 - 0.022 15.2 0.3 0.058 13.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1158) MIP PF00230.20 EGG01713.1 - 0.026 14.2 0.1 0.032 13.9 0.1 1.1 1 0 0 1 1 1 0 Major intrinsic protein COG7 PF10191.9 EGG01714.1 - 5.9e-48 163.7 21.9 1.1e-27 96.7 0.1 3.2 2 1 1 3 3 3 3 Golgi complex component 7 (COG7) DUF1884 PF08967.10 EGG01714.1 - 0.08 13.2 0.1 0.97 9.7 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1884) SNase PF00565.17 EGG01715.1 - 1.4e-27 96.3 0.0 2e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ABC1 PF03109.16 EGG01716.1 - 1.3e-24 86.6 0.0 2.4e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EGG01716.1 - 0.071 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Myb_DNA-binding PF00249.31 EGG01717.1 - 3.7e-15 55.8 0.0 8.5e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG01717.1 - 4.2e-15 55.7 0.0 3.2e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGG01717.1 - 0.0028 17.8 0.0 0.008 16.3 0.0 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Dynactin_p22 PF07426.11 EGG01719.1 - 0.27 11.1 7.3 0.19 11.6 0.3 2.5 2 0 0 2 2 2 0 Dynactin subunit p22 PIEZO PF15917.5 EGG01719.1 - 1.2 8.6 5.1 0.15 11.5 0.3 1.8 2 0 0 2 2 2 0 Piezo Fib_alpha PF08702.10 EGG01719.1 - 2.1 8.5 6.7 1.5 9.0 1.2 3.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family eIF-5a PF01287.20 EGG01720.1 - 4.6e-25 87.5 0.1 6.3e-25 87.1 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EGG01720.1 - 0.084 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Peptidase_C65 PF10275.9 EGG01721.1 - 1.8e-51 175.0 0.0 6.7e-51 173.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 EGG01721.1 - 0.00011 22.7 0.0 0.15 12.5 0.0 2.4 2 0 0 2 2 2 2 OTU-like cysteine protease FANCI_S3 PF14677.6 EGG01721.1 - 0.49 10.1 3.6 9 5.9 0.7 2.2 2 0 0 2 2 2 0 FANCI solenoid 3 UCH PF00443.29 EGG01722.1 - 2.6e-44 151.6 0.0 3.4e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG01722.1 - 8.4e-12 45.3 9.5 4.7e-05 23.1 5.3 3.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGG01722.1 - 1.9e-07 30.7 0.0 5.5e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Histone PF00125.24 EGG01723.1 - 4.8e-06 27.0 0.0 5.7e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FANCI_HD2 PF14680.6 EGG01723.1 - 0.0087 15.3 0.2 0.0097 15.2 0.2 1.0 1 0 0 1 1 1 1 FANCI helical domain 2 Methyltransf_25 PF13649.6 EGG01724.1 - 3.1e-12 47.0 0.0 4.5e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG01724.1 - 5.3e-11 43.0 0.0 7.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG01724.1 - 4.6e-08 33.0 0.0 6.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EGG01724.1 - 8e-05 22.4 0.0 8.9e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 EGG01724.1 - 0.0006 19.7 0.0 0.00097 19.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGG01724.1 - 0.003 17.5 0.0 0.0035 17.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG01724.1 - 0.022 15.5 0.0 0.033 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EGG01724.1 - 0.071 12.4 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Proton_antipo_M PF00361.20 EGG01725.1 - 8.8e-10 38.3 0.0 1.3e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Proton-conducting membrane transporter ATP-synt_ab PF00006.25 EGG01727.1 - 2.3e-61 207.1 0.0 3.5e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGG01727.1 - 3.7e-23 81.8 1.4 7.6e-23 80.8 1.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 EGG01727.1 - 0.016 14.5 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 EGG01727.1 - 0.026 14.4 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EGG01727.1 - 0.03 14.2 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 EGG01727.1 - 0.045 12.9 0.2 0.11 11.7 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 EGG01727.1 - 0.068 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGG01727.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 EGG01727.1 - 0.09 13.1 0.5 0.25 11.7 0.2 1.8 2 0 0 2 2 2 0 AAA domain F-box-like PF12937.7 EGG01728.1 - 0.00044 20.1 0.6 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGG01728.1 - 0.16 11.9 1.8 4.6 7.2 0.2 3.2 4 0 0 4 4 4 0 F-box domain CMAS PF02353.20 EGG01734.1 - 3e-20 72.6 0.0 1.5e-16 60.5 0.1 2.2 1 1 1 2 2 2 2 Mycolic acid cyclopropane synthetase DUF4218 PF13960.6 EGG01735.1 - 0.0021 17.7 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) RRM_1 PF00076.22 EGG01736.1 - 2.8e-59 196.9 0.1 2.2e-18 65.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG01736.1 - 3.7e-05 23.8 0.0 0.78 9.9 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif PHM7_cyt PF14703.6 EGG01736.1 - 0.00023 21.4 3.9 21 5.3 0.0 6.2 5 2 2 7 7 7 1 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 EGG01736.1 - 0.0016 18.3 1.0 4.1 7.2 0.0 3.9 4 0 0 4 4 4 2 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 EGG01736.1 - 0.0061 16.4 0.0 1.6 8.6 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif UPF0122 PF04297.14 EGG01736.1 - 0.0069 16.6 0.1 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like Nup35_RRM_2 PF14605.6 EGG01736.1 - 0.1 12.6 0.0 13 5.8 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif PspA_IM30 PF04012.12 EGG01740.1 - 0.015 14.9 1.1 0.028 14.0 1.1 1.5 1 0 0 1 1 1 0 PspA/IM30 family BRE1 PF08647.11 EGG01740.1 - 0.08 13.0 3.9 1.9 8.6 0.5 2.8 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase XhlA PF10779.9 EGG01740.1 - 2.9 8.1 4.3 6.6 7.0 1.4 2.9 2 1 0 2 2 2 0 Haemolysin XhlA Hema_HEFG PF02710.14 EGG01741.1 - 0.092 13.0 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein Pax7 PF12360.8 EGG01743.1 - 0.02 15.1 0.9 16 5.8 0.0 3.1 1 1 2 3 3 3 0 Paired box protein 7 zf-TRM13_CCCH PF11722.8 EGG01743.1 - 0.039 13.7 0.3 45 3.9 0.0 3.0 3 0 0 3 3 3 0 CCCH zinc finger in TRM13 protein YpM PF09144.10 EGG01743.1 - 0.15 12.2 2.8 0.36 11.0 1.1 1.9 1 1 1 2 2 2 0 Yersinia pseudo-tuberculosis mitogen Mucin PF01456.17 EGG01744.1 - 9 6.3 14.1 32 4.5 14.1 1.9 1 0 0 1 1 1 0 Mucin-like glycoprotein RhoGAP PF00620.27 EGG01745.1 - 2e-14 53.7 0.1 2.5e-07 30.7 0.0 2.1 1 1 1 2 2 2 2 RhoGAP domain DUF5491 PF17595.2 EGG01745.1 - 0.069 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5491) DUF1952 PF09189.10 EGG01745.1 - 0.091 12.6 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) Pro_isomerase PF00160.21 EGG01749.1 - 1.2e-34 119.9 0.2 1.3e-34 119.7 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Polysacc_deac_1 PF01522.21 EGG01752.1 - 9.5e-27 93.4 0.0 7.2e-26 90.5 0.0 2.0 1 1 1 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGG01752.1 - 5.8e-06 25.7 0.0 2.9e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 EGG01752.1 - 0.00012 21.8 0.0 0.0002 21.1 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) BTRD1 PF17660.1 EGG01752.1 - 0.097 12.5 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 UPF0180 PF03698.13 EGG01752.1 - 0.14 12.3 0.0 5 7.4 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) Ilm1 PF10311.9 EGG01755.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 NPV_P10 PF05531.12 EGG01756.1 - 0.00091 19.6 4.5 1.1 9.8 0.3 3.4 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein DLP_helical PF18709.1 EGG01756.1 - 0.0028 16.9 0.5 0.0028 16.9 0.5 2.9 1 1 2 4 4 4 1 Dynamin-like helical domain LPP PF04728.13 EGG01756.1 - 0.0031 17.9 7.5 0.57 10.6 0.4 4.2 3 1 0 3 3 3 1 Lipoprotein leucine-zipper DUF5082 PF16888.5 EGG01756.1 - 0.0089 16.3 4.2 0.0089 16.3 4.2 2.3 1 1 0 2 2 2 1 Domain of unknown function (DUF5082) DUF4780 PF16012.5 EGG01756.1 - 0.011 15.2 0.7 1.4 8.3 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4780) MCC-bdg_PDZ PF10506.9 EGG01756.1 - 0.014 15.4 1.5 0.014 15.4 1.5 2.7 3 0 0 3 3 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DASH_Hsk3 PF08227.11 EGG01756.1 - 0.027 14.8 1.1 0.027 14.8 1.1 3.6 5 1 0 5 5 2 0 DASH complex subunit Hsk3 like RasGAP_C PF03836.15 EGG01756.1 - 0.033 14.3 17.9 0.76 9.9 0.4 3.3 1 1 2 3 3 3 0 RasGAP C-terminus DUF2459 PF09601.10 EGG01756.1 - 0.047 13.5 0.9 8.3 6.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) Prominin PF05478.11 EGG01756.1 - 0.072 11.0 10.4 0.089 10.7 5.2 2.0 2 0 0 2 2 2 0 Prominin Cytochrom_C_2 PF01322.20 EGG01756.1 - 0.097 13.6 0.4 0.48 11.3 0.0 2.3 2 1 1 3 3 3 0 Cytochrome C' SlyX PF04102.12 EGG01756.1 - 0.12 13.0 14.0 1 10.1 0.3 4.3 3 1 1 4 4 4 0 SlyX DASH_Dad2 PF08654.10 EGG01756.1 - 0.14 12.6 5.4 9.8 6.7 0.3 3.6 1 1 2 3 3 3 0 DASH complex subunit Dad2 FlxA PF14282.6 EGG01756.1 - 0.17 11.9 17.3 0.66 10.0 1.4 4.3 2 1 2 4 4 4 0 FlxA-like protein Pex24p PF06398.11 EGG01756.1 - 0.21 10.5 1.0 0.37 9.7 0.1 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin ABC_tran_CTD PF16326.5 EGG01756.1 - 0.38 11.0 15.3 11 6.4 1.0 4.4 4 1 0 4 4 4 0 ABC transporter C-terminal domain DUF1664 PF07889.12 EGG01756.1 - 0.46 10.5 15.1 10 6.1 3.3 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) XhlA PF10779.9 EGG01756.1 - 0.65 10.2 10.0 0.62 10.3 0.3 3.6 4 0 0 4 4 4 0 Haemolysin XhlA PilJ PF13675.6 EGG01756.1 - 0.76 9.8 5.9 1.6 8.8 0.2 3.4 2 1 3 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fzo_mitofusin PF04799.13 EGG01756.1 - 0.84 9.2 14.3 1.5 8.4 2.3 3.4 2 1 0 3 3 3 0 fzo-like conserved region FlaC_arch PF05377.11 EGG01756.1 - 1.1 9.7 0.1 1.1 9.7 0.1 4.0 5 0 0 5 5 4 0 Flagella accessory protein C (FlaC) DUF1465 PF07323.12 EGG01756.1 - 1.3 8.8 19.0 0.8 9.5 3.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1465) Complex1_LYR_2 PF13233.6 EGG01756.1 - 1.3 9.8 12.2 13 6.6 0.4 3.3 1 1 1 2 2 2 0 Complex1_LYR-like ADIP PF11559.8 EGG01756.1 - 1.4 9.0 23.2 5 7.2 3.9 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding CRIC_ras_sig PF10534.9 EGG01756.1 - 1.8 8.8 7.5 14 5.9 0.1 3.8 1 1 1 3 3 3 0 Connector enhancer of kinase suppressor of ras CHDCT2 PF08074.11 EGG01756.1 - 2.4 8.3 13.1 0.18 12.0 3.3 2.5 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain KCNQ2_u3 PF16642.5 EGG01756.1 - 4.4 8.3 14.7 0.37 11.8 2.8 3.6 2 1 2 4 4 4 0 Unstructured region on Potassium channel subunit alpha KvLQT2 CorA PF01544.18 EGG01756.1 - 7 5.9 10.3 0.73 9.1 0.4 2.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF4404 PF14357.6 EGG01756.1 - 7.9 7.2 19.6 0.68 10.6 1.8 4.1 2 2 2 4 4 4 0 Domain of unknown function (DUF4404) CPSase_L_D3 PF02787.19 EGG01756.1 - 8 6.8 7.7 4.9 7.5 0.2 2.9 1 1 1 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CHASE3 PF05227.13 EGG01760.1 - 0.58 10.1 0.0 0.58 10.1 0.0 3.8 4 1 0 4 4 4 0 CHASE3 domain PRIMA1 PF16101.5 EGG01761.1 - 0.28 11.2 1.7 10 6.2 0.0 2.8 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 FXMRP1_C_core PF12235.8 EGG01762.1 - 0.0037 17.9 14.9 0.0045 17.6 14.9 1.2 1 0 0 1 1 1 1 Fragile X-related 1 protein core C terminal PPP4R2 PF09184.11 EGG01762.1 - 0.44 10.1 7.5 0.52 9.9 7.5 1.1 1 0 0 1 1 1 0 PPP4R2 SRP68 PF16969.5 EGG01764.1 - 2.5e-56 191.9 12.1 5.2e-56 190.8 12.1 1.4 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Anp1 PF03452.14 EGG01764.1 - 0.47 9.8 3.7 1.1 8.6 3.7 1.6 1 0 0 1 1 1 0 Anp1 Cgr1 PF03879.14 EGG01769.1 - 2.8e-17 63.1 19.1 3.1e-17 62.9 19.1 1.0 1 0 0 1 1 1 1 Cgr1 family tRNA_bind_2 PF13725.6 EGG01769.1 - 0.1 12.3 6.7 0.12 12.1 6.7 1.1 1 0 0 1 1 1 0 Possible tRNA binding domain Alpha_kinase PF02816.18 EGG01772.1 - 1.3e-15 58.1 0.0 2.1e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family MMPL PF03176.15 EGG01773.1 - 0.16 10.8 1.1 0.18 10.7 1.1 1.1 1 0 0 1 1 1 0 MMPL family T2SSC PF11356.8 EGG01773.1 - 0.45 10.4 2.9 0.63 9.9 2.9 1.3 1 0 0 1 1 1 0 Type II secretion system protein C Chs7 PF12271.8 EGG01774.1 - 2.8e-115 384.6 17.5 3.3e-115 384.4 17.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF2070 PF09843.9 EGG01774.1 - 9.4 4.4 24.3 17 3.5 24.3 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) F-box-like PF12937.7 EGG01775.1 - 0.041 13.8 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 F-box-like zf-DNL PF05180.12 EGG01775.1 - 0.056 13.4 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 DNL zinc finger PRMT5 PF05185.16 EGG01776.1 - 0.016 15.1 0.2 0.032 14.1 0.2 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DUF4744 PF15918.5 EGG01777.1 - 6.7e-06 26.9 0.2 1.1e-05 26.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4744) ABC_tran_Xtn PF12848.7 EGG01780.1 - 0.0023 17.9 5.5 0.0068 16.4 5.5 1.8 1 0 0 1 1 1 1 ABC transporter Ndc1_Nup PF09531.10 EGG01780.1 - 1.3 7.6 10.4 2.4 6.8 10.4 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Allexi_40kDa PF05549.11 EGG01780.1 - 1.5 8.3 4.1 2.4 7.6 4.1 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF908 PF06012.12 EGG01780.1 - 8.9 5.6 11.7 14 5.0 11.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Fe-S_biosyn PF01521.20 EGG01781.1 - 5.4e-10 39.5 0.0 5.9e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis CwsA PF10814.8 EGG01782.1 - 1.4 9.1 5.0 0.46 10.6 1.0 2.2 2 1 1 3 3 3 0 Cell wall synthesis protein CwsA DUF4192 PF13830.6 EGG01782.1 - 5.1 7.1 6.1 0.54 10.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Prok-RING_1 PF14446.6 EGG01785.1 - 0.015 15.3 0.1 0.038 13.9 0.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Ribosomal_L3 PF00297.22 EGG01786.1 - 6.1e-188 624.3 14.0 6.9e-188 624.2 14.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Pam16 PF03656.13 EGG01787.1 - 2.7e-15 56.5 1.2 6.4e-15 55.3 1.2 1.5 1 1 0 1 1 1 1 Pam16 BAH PF01426.18 EGG01789.1 - 2.8e-15 56.2 0.1 5.2e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 BAH domain DUF4614 PF15391.6 EGG01789.1 - 0.41 10.6 6.4 1 9.3 6.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF780 PF05611.11 EGG01791.1 - 0.0015 19.3 2.8 13 6.7 0.1 3.2 3 0 0 3 3 3 2 Caenorhabditis elegans protein of unknown function (DUF780) BRCT PF00533.26 EGG01791.1 - 0.035 14.5 1.2 8.5 6.8 0.1 3.0 3 1 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Antimicrobial17 PF08129.11 EGG01791.1 - 0.065 13.2 0.3 81 3.3 0.0 3.1 3 0 0 3 3 3 0 Alpha/beta enterocin family Zn_clus PF00172.18 EGG01791.1 - 0.076 13.1 1.9 57 3.9 0.0 3.4 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4766 PF15973.5 EGG01791.1 - 0.69 10.5 9.8 15 6.2 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4766) CxC5 PF18718.1 EGG01794.1 - 3.4e-33 114.2 3.7 8.2e-33 113.0 3.7 1.7 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG01794.1 - 5.3e-20 71.4 2.6 1.4e-19 70.1 2.6 1.8 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases Kunitz_BPTI PF00014.23 EGG01794.1 - 0.034 14.4 0.4 0.11 12.7 0.4 1.9 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain NAD_binding_1 PF00175.21 EGG01795.1 - 1.6e-24 86.6 0.0 3e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGG01795.1 - 1.8e-16 60.3 0.0 8.9e-16 58.1 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGG01795.1 - 5.8e-05 23.3 0.0 0.00085 19.5 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Peroxin-3 PF04882.12 EGG01796.1 - 3.4e-121 405.5 0.0 3.9e-121 405.3 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 RE_HpaII PF09561.10 EGG01797.1 - 0.012 15.1 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 HpaII restriction endonuclease CBM_19 PF03427.13 EGG01798.1 - 0.00046 20.1 0.8 0.00046 20.1 0.8 2.2 2 0 0 2 2 2 1 Carbohydrate binding domain (family 19) Ribosomal_S14 PF00253.21 EGG01800.1 - 7.2e-13 48.1 3.6 7.8e-13 48.0 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e CxC5 PF18718.1 EGG01802.1 - 8.1e-24 83.9 3.6 2.5e-23 82.4 3.6 1.9 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG01802.1 - 2.8e-20 72.4 0.9 1.1e-19 70.4 0.9 2.2 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases Alpha_kinase PF02816.18 EGG01802.1 - 1.5e-08 35.0 0.1 1.5e-08 35.0 0.1 1.8 2 0 0 2 2 2 1 Alpha-kinase family Zip PF02535.22 EGG01802.1 - 1.1 8.3 3.5 1.8 7.7 3.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter zf-CCHC PF00098.23 EGG01803.1 - 0.00046 20.1 0.3 0.00085 19.3 0.3 1.4 1 0 0 1 1 1 1 Zinc knuckle Alpha_kinase PF02816.18 EGG01804.1 - 0.0011 19.1 0.0 0.0017 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family F-box-like PF12937.7 EGG01805.1 - 0.075 12.9 0.0 0.21 11.5 0.0 1.8 1 1 0 1 1 1 0 F-box-like MCM PF00493.23 EGG01806.1 - 5.7e-12 45.2 0.8 1e-07 31.3 0.2 2.0 1 1 1 2 2 2 2 MCM P-loop domain Sel1 PF08238.12 EGG01807.1 - 9.7e-23 80.1 10.3 7.7e-08 32.8 0.2 4.0 4 1 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.6 EGG01807.1 - 0.07 13.8 0.4 2.4 8.9 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat HPS3_Mid PF14762.6 EGG01807.1 - 0.075 11.8 0.2 0.41 9.4 0.2 1.9 1 1 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region DUF2894 PF11445.8 EGG01811.1 - 2 8.8 9.5 1.3 9.5 5.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Tyr-DNA_phospho PF06087.12 EGG01812.1 - 2.1e-15 56.5 0.2 4.5e-15 55.5 0.2 1.4 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase DUF1870 PF08965.10 EGG01815.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) DPBB_1 PF03330.18 EGG01817.1 - 0.00041 20.6 0.0 0.00089 19.5 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase DUF3896 PF13035.6 EGG01818.1 - 0.37 11.0 2.5 31 4.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) RhoGAP PF00620.27 EGG01819.1 - 3.3e-48 163.4 1.7 1.4e-47 161.3 0.2 2.6 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EGG01819.1 - 1.1e-15 57.6 15.7 3.1e-09 36.9 6.4 2.9 3 0 0 3 3 2 2 LIM domain C1_1 PF00130.22 EGG01819.1 - 4.5e-06 26.5 3.1 4.5e-06 26.5 3.1 4.3 2 1 2 4 4 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3450 PF11932.8 EGG01819.1 - 0.0033 16.8 6.8 0.0033 16.8 6.8 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Strumpellin PF10266.9 EGG01819.1 - 0.013 13.2 4.4 0.021 12.5 4.4 1.3 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin DUF2685 PF10886.8 EGG01819.1 - 0.14 12.4 0.2 0.38 11.0 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) MCM_N PF14551.6 EGG01819.1 - 0.29 11.8 2.4 4.8 7.8 0.1 2.7 2 0 0 2 2 2 0 MCM N-terminal domain FAM184 PF15665.5 EGG01819.1 - 1.5 8.5 30.1 0.62 9.8 8.7 2.5 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Sec8_exocyst PF04048.14 EGG01819.1 - 2.3 8.1 12.4 0.23 11.3 3.9 2.7 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain ZapB PF06005.12 EGG01819.1 - 2.4 8.7 26.3 0.44 11.0 5.6 3.8 2 1 1 3 3 3 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 EGG01819.1 - 3.7 7.6 34.0 1.2 9.3 18.7 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1759 PF03564.15 EGG01819.1 - 5.2 7.0 7.2 2.1 8.3 1.2 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1759) PI3K_P85_iSH2 PF16454.5 EGG01819.1 - 8.6 5.9 23.0 0.4 10.2 3.0 2.8 1 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Suppressor_APC PF11414.8 EGG01819.1 - 8.7 6.5 10.6 0.6 10.2 1.2 3.5 3 1 1 4 4 4 0 Adenomatous polyposis coli tumour suppressor protein UQ_con PF00179.26 EGG01820.1 - 3.5e-28 98.0 0.0 4.2e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGG01820.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain zf-Tim10_DDP PF02953.15 EGG01821.1 - 2.3e-20 72.0 0.4 2.9e-20 71.7 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger AAA_18 PF13238.6 EGG01825.1 - 1.8e-05 25.3 0.0 4.2e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG01825.1 - 8.2e-05 22.8 0.0 0.00013 22.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG01825.1 - 0.0054 17.1 0.0 0.0077 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EGG01825.1 - 0.0057 16.0 0.0 0.0093 15.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 EGG01825.1 - 0.021 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 EGG01825.1 - 0.026 14.3 0.0 0.059 13.1 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EGG01825.1 - 0.065 13.0 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGG01825.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 EGG01825.1 - 0.16 11.7 0.4 0.26 11.0 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase ABC_tran PF00005.27 EGG01825.1 - 0.16 12.5 0.0 0.31 11.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Ribosomal_S8e PF01201.22 EGG01826.1 - 4.7e-57 192.0 2.4 5.7e-57 191.7 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Sel1 PF08238.12 EGG01827.1 - 1e-16 60.9 8.1 2.7e-07 31.0 0.6 3.6 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.6 EGG01827.1 - 0.76 10.5 3.0 28 5.6 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 EGG01829.1 - 1.9 9.5 6.3 5.7 8.0 0.0 4.1 5 0 0 5 5 5 0 WD domain, G-beta repeat RRM_1 PF00076.22 EGG01830.1 - 6.2e-39 131.7 0.0 1.4e-14 53.6 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGG01830.1 - 6.1e-06 26.2 0.0 0.0073 16.3 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif RRM_5 PF13893.6 EGG01830.1 - 0.00026 20.6 0.0 0.052 13.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGG01830.1 - 0.0012 18.9 0.1 2.7 8.2 0.0 3.4 3 1 0 3 3 3 1 Limkain b1 DUF5635 PF18685.1 EGG01830.1 - 0.13 12.2 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5635) RRM_Rrp7 PF17799.1 EGG01830.1 - 0.15 11.9 0.0 9.3 6.0 0.0 2.7 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain FNIP PF05725.12 EGG01832.1 - 0.31 11.2 4.0 13 6.1 0.0 3.3 3 0 0 3 3 3 0 FNIP Repeat DUF5635 PF18685.1 EGG01833.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5635) RESP18 PF14948.6 EGG01833.1 - 5.6 7.3 6.4 0.76 10.1 0.4 2.5 2 1 1 3 3 3 0 RESP18 domain FOLN PF09289.10 EGG01835.1 - 0.039 14.1 0.4 0.091 13.0 0.4 1.7 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain TPPII PF12580.8 EGG01835.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II DotU PF09850.9 EGG01836.1 - 0.0043 16.8 0.1 0.022 14.5 0.0 2.0 1 1 1 2 2 2 1 Type VI secretion system protein DotU TNFR_16_TM PF18422.1 EGG01836.1 - 0.24 11.4 3.8 0.5 10.4 3.8 1.6 1 1 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Alpha_kinase PF02816.18 EGG01837.1 - 1.2e-17 64.6 0.1 2e-17 63.9 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family zf-RING_4 PF14570.6 EGG01837.1 - 3.6 7.4 7.6 1.5 8.7 3.5 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain AMP-binding PF00501.28 EGG01838.1 - 2.4e-91 306.4 0.1 2.9e-91 306.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG01838.1 - 7.4e-25 87.7 0.3 2.2e-24 86.2 0.3 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGG01838.1 - 7.1e-21 73.9 0.7 4.5e-20 71.3 0.8 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus IMS PF00817.20 EGG01839.1 - 4.7e-40 137.0 0.0 7.6e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EGG01839.1 - 3.3e-06 27.8 0.0 7.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EGG01839.1 - 6.3e-05 23.1 0.1 0.00021 21.4 0.1 1.9 1 0 0 1 1 1 1 IMS family HHH motif zf_UBZ PF18439.1 EGG01839.1 - 0.084 12.5 9.3 1.9 8.2 2.2 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger PTPRCAP PF15713.5 EGG01839.1 - 2.1 8.6 11.7 5.9 7.2 11.7 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Pkinase PF00069.25 EGG01840.1 - 3.7e-54 183.8 0.0 5.1e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG01840.1 - 3.3e-31 108.5 0.0 1.8e-30 106.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG01840.1 - 0.00012 22.1 0.1 0.091 12.7 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG01840.1 - 0.00014 21.3 0.0 0.00049 19.5 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGG01840.1 - 0.00018 20.4 0.0 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGG01840.1 - 0.0033 17.0 0.1 0.006 16.1 0.1 1.5 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 EGG01840.1 - 0.0062 15.5 0.2 0.0086 15.1 0.2 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EGG01840.1 - 0.028 14.0 0.6 0.046 13.3 0.6 1.4 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.14 EGG01840.1 - 0.055 12.8 0.1 0.083 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nudix_N PF12535.8 EGG01840.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Choline_kinase PF01633.20 EGG01840.1 - 0.1 12.2 0.4 0.16 11.6 0.4 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 EGG01840.1 - 0.16 11.6 0.1 0.24 11.0 0.1 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 LHH PF14411.6 EGG01840.1 - 0.28 11.4 1.0 0.81 9.9 0.0 2.2 3 0 0 3 3 3 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH LIM PF00412.22 EGG01842.1 - 6.5e-24 83.9 23.5 4.7e-12 45.9 12.0 2.2 2 0 0 2 2 2 2 LIM domain Med16 PF11635.8 EGG01842.1 - 0.58 8.0 1.9 0.82 7.5 1.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 Glyco_hydro_15 PF00723.21 EGG01845.1 - 3.2e-71 240.4 0.4 3.9e-71 240.2 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 TPR_1 PF00515.28 EGG01849.1 - 2.7e-50 166.2 19.8 8e-06 25.5 0.0 10.1 9 1 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 EGG01849.1 - 2.4e-45 149.0 15.5 1.6e-05 24.6 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 EGG01849.1 - 8.1e-36 119.2 13.8 9.8e-05 22.3 0.3 9.9 10 1 0 10 10 9 8 Tetratricopeptide repeat TPR_14 PF13428.6 EGG01849.1 - 2.8e-31 105.5 3.3 0.00086 19.9 0.0 9.4 3 3 7 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 EGG01849.1 - 5.2e-27 94.2 5.3 1.1e-07 32.3 0.1 6.8 3 2 4 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.6 EGG01849.1 - 3.4e-23 80.3 10.4 9e-05 22.6 0.1 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGG01849.1 - 1.7e-20 73.2 5.7 0.0016 18.9 0.0 7.1 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGG01849.1 - 3.2e-20 71.5 23.8 0.00021 20.9 0.5 8.2 5 1 1 7 7 7 5 TPR repeat TPR_6 PF13174.6 EGG01849.1 - 6.3e-20 70.4 10.3 0.03 15.0 0.0 9.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGG01849.1 - 2.8e-18 66.0 21.7 0.0013 19.0 1.6 7.8 4 3 1 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGG01849.1 - 2.9e-16 58.2 23.8 0.0059 16.6 0.0 9.6 8 3 1 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGG01849.1 - 2.4e-15 56.4 4.1 0.027 14.6 0.0 6.3 2 2 3 6 6 6 4 Tetratricopeptide repeat SNAP PF14938.6 EGG01849.1 - 3.3e-09 36.6 4.7 5.6e-05 22.7 0.1 4.1 2 2 2 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_15 PF13429.6 EGG01849.1 - 5.2e-09 35.7 4.6 0.053 12.7 0.1 5.4 2 2 4 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG01849.1 - 6.2e-08 32.8 11.8 0.0035 17.5 0.7 3.7 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 EGG01849.1 - 2.6e-06 27.3 0.9 0.083 12.6 0.0 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 EGG01849.1 - 1.6e-05 24.7 0.3 0.0012 18.6 0.0 3.0 1 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) NARP1 PF12569.8 EGG01849.1 - 0.00017 20.7 2.7 0.32 9.9 0.0 3.7 2 1 1 4 4 4 2 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 EGG01849.1 - 0.00048 19.6 1.6 0.11 11.9 0.1 3.8 2 1 1 3 3 3 1 MalT-like TPR region MIT PF04212.18 EGG01849.1 - 0.0038 17.3 13.3 3.3 7.8 0.0 6.0 7 0 0 7 7 7 1 MIT (microtubule interacting and transport) domain RPN7 PF10602.9 EGG01849.1 - 0.027 14.2 6.1 7.6 6.2 0.0 5.6 3 2 4 7 7 7 0 26S proteasome subunit RPN7 DUF4919 PF16266.5 EGG01849.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) TPR_10 PF13374.6 EGG01849.1 - 0.2 11.6 15.9 13 5.8 0.1 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF3808 PF10300.9 EGG01849.1 - 0.21 10.3 1.2 3.4 6.3 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF3808) DUF410 PF04190.13 EGG01849.1 - 0.26 11.1 2.0 18 5.0 0.1 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF410) Sel1 PF08238.12 EGG01849.1 - 0.33 11.7 8.4 1.2 9.9 0.0 4.8 5 1 0 5 5 5 0 Sel1 repeat DUF1965 PF09248.10 EGG01849.1 - 0.59 9.9 5.3 5.2 6.9 0.4 4.0 2 2 3 5 5 5 0 Domain of unknown function (DUF1965) TOM20_plant PF06552.12 EGG01849.1 - 0.75 9.5 2.7 7 6.3 0.1 3.7 4 2 1 5 5 4 0 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.6 EGG01849.1 - 1.1 9.4 6.7 24 5.1 0.0 4.7 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat PMM PF03332.13 EGG01852.1 - 0.0011 18.8 0.3 0.0012 18.6 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Mod_r PF07200.13 EGG01852.1 - 0.052 13.6 0.7 0.077 13.1 0.5 1.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein RIX1 PF08167.12 EGG01855.1 - 1.7e-16 60.5 2.3 1.7e-16 60.5 2.3 2.7 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Ilm1 PF10311.9 EGG01855.1 - 0.049 13.3 0.1 0.09 12.4 0.1 1.4 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 Acetyltransf_1 PF00583.25 EGG01856.1 - 2.5e-15 56.8 0.0 2.9e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG01856.1 - 8.1e-10 38.7 0.1 9.3e-10 38.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG01856.1 - 5.6e-07 29.4 0.0 7.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGG01856.1 - 2.5e-06 27.8 0.0 3.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGG01856.1 - 0.0035 17.4 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGG01856.1 - 0.043 14.5 0.0 0.15 12.7 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGG01856.1 - 0.045 13.2 0.1 0.063 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative acetyl-transferase DUF489 PF04356.12 EGG01857.1 - 0.0091 16.0 3.8 0.046 13.7 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF489) Chordopox_A13L PF05961.11 EGG01859.1 - 0.068 13.4 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF4834 PF16118.5 EGG01859.1 - 0.077 14.0 0.0 0.077 14.0 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) DUF2104 PF09877.9 EGG01859.1 - 0.097 12.9 0.6 0.17 12.2 0.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) SNARE_assoc PF09335.11 EGG01859.1 - 0.16 12.5 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein Aldose_epim PF01263.20 EGG01860.1 - 1.2e-52 179.1 0.0 1.5e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase RCC1 PF00415.18 EGG01861.1 - 1.2e-22 80.3 8.6 0.00025 21.6 0.0 6.6 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 EGG01861.1 - 1.4e-08 35.2 0.0 3.8e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.6 EGG01861.1 - 1.2e-07 31.3 8.5 1e-06 28.4 0.1 4.0 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 EGG01861.1 - 1.4e-07 32.0 0.1 4.8e-07 30.2 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) BTB PF00651.31 EGG01861.1 - 3.7e-07 30.3 0.2 5.3e-05 23.4 0.0 3.1 2 1 1 3 3 3 1 BTB/POZ domain Ank_3 PF13606.6 EGG01861.1 - 0.0001 22.4 0.4 0.0053 17.2 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EGG01861.1 - 0.002 18.5 0.1 0.0072 16.7 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 EGG01861.1 - 0.014 15.7 0.2 0.055 13.8 0.1 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) BACK PF07707.15 EGG01861.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch Apis_Csd PF11671.8 EGG01862.1 - 0.028 14.5 8.6 0.079 13.0 8.6 1.7 1 0 0 1 1 1 0 Complementary sex determiner protein Noggin PF05806.12 EGG01862.1 - 2.9 7.8 8.4 6.4 6.6 8.4 1.5 1 0 0 1 1 1 0 Noggin Presenilin PF01080.17 EGG01862.1 - 9.7 4.8 7.7 16 4.1 7.7 1.4 1 0 0 1 1 1 0 Presenilin Alpha_kinase PF02816.18 EGG01864.1 - 6.8e-18 65.4 0.0 9e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family DUF2793 PF10983.8 EGG01866.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) Pkinase PF00069.25 EGG01867.1 - 5.6e-58 196.4 0.0 7.1e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG01867.1 - 1.2e-40 139.5 0.0 1.5e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG01867.1 - 0.00034 19.5 0.0 0.00059 18.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGG01867.1 - 0.0006 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGG01867.1 - 0.0088 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EGG01867.1 - 0.025 14.2 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGG01867.1 - 0.064 13.2 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG01867.1 - 0.091 12.1 0.3 0.14 11.5 0.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PBP PF01161.20 EGG01869.1 - 1.8e-17 63.9 0.3 4e-17 62.8 0.1 1.7 1 1 1 2 2 2 1 Phosphatidylethanolamine-binding protein KDZ PF18758.1 EGG01870.1 - 1e-08 35.1 0.1 5e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CSN5_C PF18323.1 EGG01870.1 - 0.0051 17.7 2.9 0.76 10.7 0.5 2.2 1 1 1 2 2 2 2 Cop9 signalosome subunit 5 C-terminal domain ABC_tran_CTD PF16326.5 EGG01870.1 - 0.0098 16.1 0.5 0.0098 16.1 0.5 2.8 2 1 1 3 3 3 1 ABC transporter C-terminal domain DUF4255 PF14065.6 EGG01870.1 - 0.037 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) Peptidase_M3_N PF08439.10 EGG01870.1 - 0.41 11.0 2.7 0.58 10.5 1.4 2.0 2 0 0 2 2 2 0 Oligopeptidase F CCDC-167 PF15188.6 EGG01870.1 - 0.76 10.2 5.0 2.4 8.6 5.0 1.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 EMP24_GP25L PF01105.24 EGG01870.1 - 1.1 9.2 4.5 3.3 7.6 4.5 1.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Ctr PF04145.15 EGG01871.1 - 1.6e-29 103.4 0.0 2.5e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Ctr copper transporter family DnaJ PF00226.31 EGG01874.1 - 1.7e-11 44.0 0.0 4.7e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 EGG01874.1 - 0.079 13.5 0.0 0.32 11.5 0.0 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat Drf_DAD PF06345.11 EGG01874.1 - 0.14 12.3 0.6 0.77 9.9 0.0 2.3 2 0 0 2 2 2 0 DRF Autoregulatory Domain GvpG PF05120.12 EGG01874.1 - 0.38 10.8 2.5 4 7.5 0.8 2.7 2 0 0 2 2 2 0 Gas vesicle protein G DUF5107 PF17128.4 EGG01877.1 - 0.094 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5107) ArfGap PF01412.18 EGG01879.1 - 3.1e-21 75.6 0.1 3.3e-21 75.6 0.1 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ProRS-C_1 PF09180.11 EGG01879.1 - 0.038 14.2 0.1 0.062 13.5 0.1 1.4 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal zf-B_box PF00643.24 EGG01879.1 - 0.083 13.1 0.9 0.26 11.5 0.9 1.7 1 1 0 1 1 1 0 B-box zinc finger DUF3973 PF13119.6 EGG01879.1 - 0.086 12.9 1.7 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) Flavin_Reduct PF01613.18 EGG01880.1 - 3.4e-22 79.2 0.0 4.5e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 EGG01880.1 - 0.063 13.0 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF447) Clathrin PF00637.20 EGG01882.1 - 1.5e-202 663.6 33.9 2.1e-33 115.2 2.1 7.3 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EGG01882.1 - 1.7e-33 114.3 0.2 4.8e-33 112.9 0.2 1.9 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.20 EGG01882.1 - 2.5e-32 109.6 0.0 3.5e-06 27.1 0.1 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin-link PF09268.10 EGG01882.1 - 1e-12 47.1 0.1 2.3e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_1 PF00515.28 EGG01882.1 - 7.6e-05 22.4 1.0 10 6.1 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EGG01882.1 - 0.00018 20.7 4.2 0.24 10.4 0.1 3.8 5 0 0 5 5 5 2 Coatomer WD associated region TPR_2 PF07719.17 EGG01882.1 - 0.0095 16.0 3.3 14 6.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG01882.1 - 0.013 15.5 4.9 1.9 8.7 0.3 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG01882.1 - 0.62 11.0 19.4 41 5.4 0.2 9.3 10 3 1 11 11 11 0 Tetratricopeptide repeat 4HBT_3 PF13622.6 EGG01883.1 - 3.2e-53 181.5 0.0 4e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EGG01883.1 - 9.6e-23 80.5 0.3 5.5e-19 68.3 0.0 2.8 2 1 0 2 2 2 2 Acyl-CoA thioesterase Ribosomal_S13 PF00416.22 EGG01885.1 - 3e-53 179.6 1.4 3.4e-53 179.4 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EGG01885.1 - 0.0058 15.4 0.0 0.0067 15.2 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 EGG01885.1 - 0.1 13.1 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) PP28 PF10252.9 EGG01885.1 - 0.11 12.9 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Complex1_LYR_2 PF13233.6 EGG01886.1 - 1.2e-18 67.6 0.0 1.6e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGG01886.1 - 7.9e-08 32.2 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) XPG_N PF00752.17 EGG01887.1 - 6.3e-35 119.7 0.0 1.5e-34 118.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGG01887.1 - 1.9e-31 108.3 0.0 7.2e-31 106.4 0.0 2.0 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 EGG01887.1 - 5.2e-06 27.0 0.0 1.6e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Retrotran_gag_2 PF14223.6 EGG01888.1 - 2.9e-10 40.0 0.7 1.2e-09 38.0 0.2 2.1 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type 6PF2K PF01591.18 EGG01889.1 - 4.9e-58 196.1 0.0 8e-58 195.4 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGG01889.1 - 3.6e-24 85.6 0.0 7e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGG01889.1 - 7e-05 23.0 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGG01889.1 - 0.00018 21.0 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 FHA PF00498.26 EGG01890.1 - 1.5e-14 54.1 0.1 1.2e-13 51.1 0.0 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EGG01890.1 - 0.00073 19.8 0.0 0.043 14.1 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DnaJ PF00226.31 EGG01894.1 - 2.6e-23 81.9 2.0 9.7e-23 80.1 2.0 2.1 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 EGG01894.1 - 4e-10 39.7 0.9 4e-10 39.7 0.9 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG01894.1 - 1.9e-08 34.4 8.1 3.8e-08 33.5 0.8 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGG01894.1 - 5.3e-05 23.7 3.3 0.24 12.3 1.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EGG01894.1 - 0.00017 21.9 12.4 0.033 14.5 0.7 3.4 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EGG01894.1 - 0.00073 19.9 5.8 0.11 13.0 2.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Methyltransf_33 PF10017.9 EGG01895.1 - 3.4e-13 49.4 0.1 4e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_33 PF10017.9 EGG01896.1 - 6.4e-59 199.6 0.1 1.1e-58 198.8 0.1 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EGG01896.1 - 8.8e-13 48.4 0.0 1.5e-07 31.3 0.1 2.3 1 1 1 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EGG01896.1 - 0.00041 20.9 0.0 0.00091 19.7 0.0 1.7 1 0 0 1 1 1 1 DinB superfamily AAA_23 PF13476.6 EGG01897.1 - 2.1e-29 103.5 0.0 2.1e-29 103.5 0.0 8.3 1 1 5 6 6 6 1 AAA domain AAA_15 PF13175.6 EGG01897.1 - 1e-11 45.2 0.1 1e-11 45.2 0.1 5.4 1 1 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 EGG01897.1 - 1.2e-10 41.7 8.1 0.00019 21.3 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGG01897.1 - 2.4e-06 27.7 0.1 2.8e-05 24.3 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 EGG01897.1 - 0.00021 20.1 22.2 0.0031 16.2 22.1 6.9 2 1 4 7 7 7 3 AAA domain AAA_29 PF13555.6 EGG01897.1 - 0.00086 19.0 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EGG01897.1 - 0.0083 16.6 0.0 0.0083 16.6 0.0 6.5 3 2 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 EGG01897.1 - 0.18 12.2 0.0 0.18 12.2 0.0 5.6 5 2 0 6 6 6 0 AAA ATPase domain Golgin_A5 PF09787.9 EGG01897.1 - 6.4 6.1 133.6 0.0076 15.7 25.4 6.6 2 2 4 7 7 7 0 Golgin subfamily A member 5 RRM_1 PF00076.22 EGG01898.1 - 3.2e-45 151.8 0.8 1.3e-18 66.6 0.1 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG01898.1 - 2.8e-11 43.1 0.0 5.9e-05 22.9 0.0 4.0 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EGG01898.1 - 1e-09 38.3 0.3 0.084 13.0 0.0 4.9 4 1 0 4 4 4 3 RNA recognition motif TPR_16 PF13432.6 EGG01898.1 - 5.2e-05 23.8 0.3 0.00051 20.6 0.7 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG01898.1 - 7e-05 23.3 3.1 5.5 8.1 0.2 5.3 3 1 1 4 4 4 1 Tetratricopeptide repeat Nup35_RRM_2 PF14605.6 EGG01898.1 - 0.00059 19.8 0.0 1.5 8.8 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif TPR_2 PF07719.17 EGG01898.1 - 0.012 15.7 3.1 0.71 10.1 0.5 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat NCBP3 PF10309.9 EGG01898.1 - 0.16 11.8 0.8 5.3 7.0 0.0 3.4 3 0 0 3 3 3 0 Nuclear cap-binding protein subunit 3 PHM7_cyt PF14703.6 EGG01898.1 - 0.31 11.3 5.6 8.4 6.6 0.0 4.3 5 0 0 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter DUF702 PF05142.12 EGG01898.1 - 0.55 10.7 3.1 1.2 9.6 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF702) SET PF00856.28 EGG01899.1 - 2.6e-10 40.9 0.1 5.7e-10 39.8 0.1 1.7 1 1 0 1 1 1 1 SET domain NPV_P10 PF05531.12 EGG01899.1 - 0.046 14.2 0.1 0.11 13.0 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Macoilin PF09726.9 EGG01900.1 - 0.014 14.0 4.9 0.02 13.5 4.9 1.3 1 0 0 1 1 1 0 Macoilin family PKcGMP_CC PF16808.5 EGG01900.1 - 0.12 12.2 1.5 0.16 11.8 0.2 1.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CENP-F_N PF10481.9 EGG01900.1 - 0.14 11.8 9.3 0.26 10.9 9.3 1.4 1 0 0 1 1 1 0 Cenp-F N-terminal domain Presenilin PF01080.17 EGG01900.1 - 2.4 6.8 5.2 3.7 6.2 5.2 1.2 1 0 0 1 1 1 0 Presenilin Nop25 PF09805.9 EGG01900.1 - 5.3 7.5 10.1 0.73 10.3 0.4 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Fez1 PF06818.15 EGG01900.1 - 6.2 7.2 9.6 11 6.5 9.4 1.6 1 1 0 1 1 1 0 Fez1 Rtf2 PF04641.12 EGG01900.1 - 7.7 5.8 11.5 15 4.8 11.5 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger GCD14 PF08704.10 EGG01901.1 - 8.9e-75 251.5 0.0 1e-74 251.4 0.0 1.0 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 EGG01901.1 - 1.2e-06 28.4 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGG01901.1 - 0.00019 21.3 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EGG01901.1 - 0.056 14.1 0.0 0.094 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GCD14_N PF14801.6 EGG01901.1 - 0.076 12.9 0.0 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term Fibrillarin PF01269.17 EGG01901.1 - 0.13 11.4 0.0 0.43 9.7 0.0 1.7 2 0 0 2 2 2 0 Fibrillarin Las1 PF04031.13 EGG01903.1 - 1.1e-33 116.6 0.0 2.4e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 Las1-like DUF2486 PF10667.9 EGG01903.1 - 0.0011 19.2 0.1 0.0019 18.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2486) Baculo_PEP_C PF04513.12 EGG01905.1 - 0.01 15.9 0.5 0.023 14.7 0.5 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran_CTD PF16326.5 EGG01905.1 - 0.12 12.6 7.4 0.21 11.8 0.0 3.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain Chal_sti_synt_C PF02797.15 EGG01905.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain T2SSF PF00482.23 EGG01905.1 - 0.18 11.7 1.9 14 5.7 1.5 2.2 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F OmpH PF03938.14 EGG01905.1 - 0.23 11.8 5.6 0.59 10.5 5.6 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) I_LWEQ PF01608.17 EGG01905.1 - 0.85 9.8 10.9 1.9 8.7 7.9 2.5 1 1 1 2 2 2 0 I/LWEQ domain SWIRM-assoc_1 PF16495.5 EGG01905.1 - 6.4 6.8 12.8 1.4 8.9 7.4 2.6 2 1 0 3 3 3 0 SWIRM-associated region 1 DTHCT PF08070.11 EGG01906.1 - 0.066 14.0 16.1 0.1 13.3 16.1 1.4 1 1 0 1 1 1 0 DTHCT (NUC029) region XRCC4 PF06632.12 EGG01906.1 - 0.84 8.4 9.2 0.94 8.3 9.2 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RGS12_us1 PF16613.5 EGG01906.1 - 2.8 8.3 11.4 1.2 9.4 6.9 2.0 1 1 1 2 2 2 0 Unstructured region of RGS12 MCM_bind PF09739.9 EGG01906.1 - 5.6 5.3 9.6 6.5 5.1 9.6 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Prenyltrans PF00432.21 EGG01907.1 - 9.8e-23 79.6 14.9 1.4e-05 24.7 0.1 6.1 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Peptidase_C54 PF03416.19 EGG01910.1 - 2.6e-14 53.3 0.0 3.1e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Met_10 PF02475.16 EGG01912.1 - 1.7e-09 37.7 0.0 3.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 EGG01912.1 - 0.03 15.0 0.0 0.07 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGG01912.1 - 0.034 13.7 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ribonuclease_3 PF00636.26 EGG01913.1 - 8.7e-12 45.6 0.1 1.8e-05 25.3 0.0 3.5 2 1 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGG01913.1 - 1.7e-07 31.4 0.1 0.013 15.7 0.0 3.3 2 1 0 2 2 2 2 Ribonuclease-III-like TM2 PF05154.16 EGG01913.1 - 0.15 12.4 0.6 0.34 11.3 0.0 1.8 2 0 0 2 2 2 0 TM2 domain Ssu72 PF04722.13 EGG01914.1 - 5.1e-82 274.1 0.0 6e-82 273.8 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein AAA PF00004.29 EGG01915.1 - 8e-41 139.6 0.0 1.4e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG01915.1 - 2.4e-10 40.1 0.4 4.6e-10 39.1 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EGG01915.1 - 1.8e-09 37.4 0.1 3.7e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EGG01915.1 - 5.2e-06 26.7 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGG01915.1 - 5.3e-06 26.8 0.3 0.004 17.4 0.3 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGG01915.1 - 2.3e-05 23.7 0.0 3.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EGG01915.1 - 8.4e-05 22.6 0.2 0.00041 20.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGG01915.1 - 0.00013 22.4 0.3 0.0057 17.1 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGG01915.1 - 0.00089 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EGG01915.1 - 0.0022 17.6 0.5 0.23 11.0 0.2 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGG01915.1 - 0.005 16.6 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase PF06745.13 EGG01915.1 - 0.0059 16.0 0.4 0.11 11.8 0.1 2.5 2 1 1 3 3 3 1 KaiC Prot_ATP_OB_N PF17758.1 EGG01915.1 - 0.011 15.4 0.7 0.054 13.1 0.0 2.4 3 0 0 3 3 2 0 Proteasomal ATPase OB N-terminal domain AAA_3 PF07726.11 EGG01915.1 - 0.015 15.1 0.1 0.066 13.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 EGG01915.1 - 0.017 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 EGG01915.1 - 0.02 14.2 0.1 0.035 13.4 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 EGG01915.1 - 0.026 14.9 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EGG01915.1 - 0.031 14.4 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGG01915.1 - 0.038 13.9 0.2 0.2 11.5 0.1 2.0 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 EGG01915.1 - 0.053 13.0 0.1 0.22 10.9 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 EGG01915.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGG01915.1 - 0.068 12.9 0.2 0.17 11.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGG01915.1 - 0.073 13.3 0.1 0.17 12.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 EGG01915.1 - 0.073 12.8 0.1 0.26 11.0 0.0 1.9 3 0 0 3 3 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 EGG01915.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGG01915.1 - 0.085 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 EGG01915.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EGG01915.1 - 0.17 11.6 0.3 0.49 10.1 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGG01915.1 - 0.17 11.4 0.1 0.39 10.2 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EGG01915.1 - 0.25 11.9 1.2 0.3 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain UBX PF00789.20 EGG01916.1 - 3.7e-11 43.1 0.2 7.6e-11 42.1 0.2 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin PF00085.20 EGG01917.1 - 4.6e-22 78.0 0.0 1e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin ERp29 PF07749.12 EGG01917.1 - 5.7e-21 75.2 0.3 5.7e-21 75.2 0.3 2.2 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EGG01917.1 - 0.00022 21.6 0.0 0.00095 19.6 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGG01917.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF5446 PF17522.2 EGG01917.1 - 0.13 12.4 1.3 0.23 11.6 1.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5446) DUF883 PF05957.13 EGG01917.1 - 0.16 12.6 3.6 0.61 10.7 2.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EGG01917.1 - 1.7 9.2 10.6 51 4.5 10.6 2.4 1 1 0 1 1 1 0 YtxH-like protein PAT1 PF09770.9 EGG01920.1 - 2.8e-122 409.7 33.0 2.7e-121 406.4 33.0 2.5 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_hydro_108 PF05838.12 EGG01921.1 - 0.18 12.3 0.0 0.2 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase 108 Cyclin_N PF00134.23 EGG01924.1 - 1.3e-05 25.0 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGG01924.1 - 0.0014 18.7 0.1 0.02 15.0 0.0 2.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain Aconitase PF00330.20 EGG01925.1 - 2e-163 544.7 0.0 2.5e-163 544.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGG01925.1 - 3.3e-37 127.7 0.0 5.7e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ustilago_mating PF05722.12 EGG01926.1 - 0.073 12.6 5.4 0.11 12.1 5.4 1.3 1 0 0 1 1 1 0 Ustilago B locus mating-type protein F-box-like PF12937.7 EGG01930.1 - 0.01 15.7 0.3 0.092 12.7 0.0 2.7 2 1 0 2 2 2 0 F-box-like F-box PF00646.33 EGG01930.1 - 0.15 12.0 2.3 2.4 8.1 0.3 2.9 2 0 0 2 2 2 0 F-box domain DHBP_synthase PF00926.19 EGG01931.1 - 9.9e-84 279.6 0.0 1.2e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase SRR1 PF07985.12 EGG01933.1 - 2.1e-07 30.9 0.0 1.8e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 SRR1 ADPRTs_Tse2 PF18648.1 EGG01933.1 - 0.14 12.2 0.0 18 5.3 0.0 2.2 1 1 1 2 2 2 0 Tse2 ADP-ribosyltransferase toxins E1-E2_ATPase PF00122.20 EGG01935.1 - 7e-49 165.8 0.1 7e-49 165.8 0.1 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGG01935.1 - 1.4e-18 68.0 1.1 4.8e-18 66.2 1.1 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGG01935.1 - 9.6e-13 47.6 0.1 2.2e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG01935.1 - 0.00048 19.9 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG01935.1 - 0.093 12.8 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Mon1 PF03164.14 EGG01936.1 - 9e-112 374.1 0.0 1.1e-111 373.8 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 GATA PF00320.27 EGG01938.1 - 1.9e-11 43.3 2.8 4e-11 42.3 2.8 1.5 1 0 0 1 1 1 1 GATA zinc finger CMAS PF02353.20 EGG01939.1 - 2.8e-64 217.0 0.0 8.6e-64 215.5 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGG01939.1 - 2e-09 38.0 0.0 5.6e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG01939.1 - 6.8e-08 33.1 0.0 1.6e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG01939.1 - 1.6e-05 25.5 0.0 0.00023 21.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG01939.1 - 2.2e-05 24.3 0.0 4.9e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG01939.1 - 0.00018 21.3 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGG01939.1 - 0.042 14.9 0.0 0.11 13.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EGG01939.1 - 0.06 13.1 0.1 0.2 11.4 0.0 1.7 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ATPase PF06745.13 EGG01939.1 - 0.097 12.0 0.0 0.74 9.1 0.0 2.0 2 0 0 2 2 2 0 KaiC GPI-anchored PF10342.9 EGG01941.1 - 6.5e-12 46.0 0.7 6.5e-12 46.0 0.7 1.8 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.9 EGG01941.1 - 1.6 7.2 3.6 1.6 7.2 3.6 1.0 1 0 0 1 1 1 0 Macoilin family DUF1295 PF06966.12 EGG01942.1 - 1.8e-49 168.4 0.2 2.7e-49 167.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EGG01942.1 - 1e-05 25.9 0.2 4.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 EGG01942.1 - 0.00051 20.0 0.0 0.00087 19.3 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EGG01942.1 - 0.0006 20.2 1.7 0.0019 18.5 0.3 2.5 1 1 1 3 3 3 1 Phospholipid methyltransferase Peptidase_S10 PF00450.22 EGG01943.1 - 1.6e-100 337.5 0.6 1.9e-100 337.2 0.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Asp PF00026.23 EGG01944.1 - 7.9e-62 209.5 1.8 1e-61 209.1 1.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG01944.1 - 2.8e-14 53.8 0.1 1e-12 48.7 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal JAB PF01398.21 EGG01945.1 - 7.8e-07 29.1 0.0 1.1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGG01946.1 - 1.2e-13 51.4 0.1 2e-13 50.7 0.1 1.3 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function Asp PF00026.23 EGG01947.1 - 1.8e-62 211.6 8.1 2.6e-62 211.1 8.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG01947.1 - 2.1e-14 54.2 7.5 5.3e-13 49.6 7.5 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGG01947.1 - 3.5e-05 24.4 3.1 1.2 9.9 0.1 3.7 2 2 2 4 4 4 2 Aspartyl protease gag-asp_proteas PF13975.6 EGG01947.1 - 0.29 11.7 1.7 28 5.3 0.3 3.5 2 2 1 3 3 3 0 gag-polyprotein putative aspartyl protease Sec1 PF00995.23 EGG01948.1 - 1.6e-129 433.8 0.1 2e-129 433.5 0.1 1.1 1 0 0 1 1 1 1 Sec1 family Fcf2 PF08698.11 EGG01949.1 - 0.056 13.8 0.1 0.11 12.9 0.1 1.6 1 1 0 1 1 1 0 Fcf2 pre-rRNA processing CD20 PF04103.15 EGG01950.1 - 0.028 14.5 0.9 0.071 13.2 0.5 1.7 2 0 0 2 2 2 0 CD20-like family O-FucT PF10250.9 EGG01951.1 - 3.6e-09 36.8 0.1 9.7e-09 35.4 0.1 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Amidohydro_1 PF01979.20 EGG01952.1 - 1.2e-64 218.8 0.5 1.8e-64 218.3 0.5 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EGG01952.1 - 1.4e-56 190.0 2.2 3e-56 188.9 2.2 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 EGG01952.1 - 5.9e-37 126.0 0.1 1.4e-36 124.8 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 EGG01952.1 - 1.5e-35 121.1 0.0 1.3e-34 118.1 0.0 2.4 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 EGG01952.1 - 0.00012 21.7 0.4 0.4 10.1 0.0 2.9 3 1 0 3 3 3 2 Amidohydrolase family APG9 PF04109.16 EGG01953.1 - 8.7e-195 648.3 5.0 1e-194 648.0 5.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 TPT PF03151.16 EGG01955.1 - 1.8e-23 83.3 21.4 2.2e-23 83.0 21.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF1118 PF06549.12 EGG01955.1 - 3.5 8.0 10.8 0.21 11.9 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) Rax2 PF12768.7 EGG01955.1 - 3.6 7.0 7.9 1.5 8.3 0.4 2.9 3 0 0 3 3 3 0 Cortical protein marker for cell polarity CD20 PF04103.15 EGG01956.1 - 0.22 11.6 2.2 0.17 12.0 0.5 1.7 2 0 0 2 2 2 0 CD20-like family RNase_P_Rpp14 PF01900.19 EGG01957.1 - 5.3e-28 97.3 0.3 6.9e-28 96.9 0.3 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family IGR PF09597.10 EGG01958.1 - 2.7e-12 46.6 0.9 5.4e-12 45.6 0.4 1.8 2 0 0 2 2 2 1 IGR protein motif FHA PF00498.26 EGG01959.1 - 2.5e-14 53.4 0.0 5.6e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGG01959.1 - 9.4e-05 22.7 0.0 0.14 12.4 0.0 2.3 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain DivIVA PF05103.13 EGG01960.1 - 7.1e-05 22.9 4.2 7.1e-05 22.9 4.2 4.1 3 1 1 4 4 4 1 DivIVA protein RED_C PF07807.11 EGG01960.1 - 0.31 11.5 4.8 0.84 10.1 0.6 2.8 2 0 0 2 2 2 0 RED-like protein C-terminal region Sa_NUDIX PF18167.1 EGG01960.1 - 0.47 10.2 10.1 0.35 10.7 7.9 1.9 1 1 1 2 2 2 0 SMODS-associated NUDIX domain Seryl_tRNA_N PF02403.22 EGG01960.1 - 0.86 9.9 22.5 5.4 7.3 4.2 4.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Myc_N PF01056.18 EGG01964.1 - 0.32 10.8 4.7 0.1 12.5 0.4 2.1 2 0 0 2 2 2 0 Myc amino-terminal region Ribosomal_L15e PF00827.17 EGG01966.1 - 1.1e-89 299.3 10.3 1.3e-89 299.0 10.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 SAPS PF04499.15 EGG01967.1 - 0.56 8.9 2.6 0.89 8.3 2.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_lid_4 PF17864.1 EGG01967.1 - 2.3 8.0 4.2 21 5.0 0.3 2.5 2 0 0 2 2 2 0 RuvB AAA lid domain TMEM154 PF15102.6 EGG01967.1 - 9 6.2 11.7 3e+02 1.2 11.7 2.9 1 1 0 1 1 1 0 TMEM154 protein family DUF4250 PF14056.6 EGG01969.1 - 0.14 12.2 0.1 0.36 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Acetyltransf_8 PF13523.6 EGG01975.1 - 1e-46 158.2 0.1 1.3e-46 157.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGG01975.1 - 4.9e-06 27.3 0.0 8.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain bZIP_1 PF00170.21 EGG01977.1 - 0.00025 21.1 0.6 0.00047 20.2 0.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGG01977.1 - 0.48 10.6 2.6 0.83 9.8 2.6 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Ice_nucleation PF00818.17 EGG01977.1 - 5.2 7.4 6.9 25 5.2 6.9 2.2 1 0 0 1 1 1 0 Ice nucleation protein repeat DUF1604 PF07713.13 EGG01978.1 - 5.9e-38 128.6 1.2 5.9e-38 128.6 1.2 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EGG01978.1 - 1.2e-07 31.5 0.3 3.4e-07 30.1 0.3 1.8 1 0 0 1 1 1 1 G-patch domain DEAD PF00270.29 EGG01979.1 - 6.6e-50 169.3 0.0 2.4e-49 167.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG01979.1 - 1.6e-31 108.9 0.0 9.7e-30 103.2 0.0 2.7 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG01979.1 - 1.6e-07 31.5 0.0 4.7e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2443 PF10398.9 EGG01979.1 - 0.0057 16.7 0.2 0.012 15.6 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2443) UTP25 PF06862.12 EGG01979.1 - 0.011 14.5 0.0 0.49 9.1 0.0 2.8 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Alginate_lyase PF05426.12 EGG01983.1 - 6e-14 52.2 0.1 8.6e-14 51.7 0.1 1.2 1 0 0 1 1 1 1 Alginate lyase Ribosomal_S17_N PF16205.5 EGG01984.1 - 0.089 13.2 1.5 0.29 11.5 0.0 2.1 2 0 0 2 2 2 0 Ribosomal_S17 N-terminal KAsynt_C_assoc PF16197.5 EGG01984.1 - 0.16 12.5 1.1 0.44 11.0 0.6 1.8 1 1 1 2 2 2 0 Ketoacyl-synthetase C-terminal extension FidL_like PF15941.5 EGG01984.1 - 0.18 12.3 1.4 0.26 11.8 1.4 1.3 1 0 0 1 1 1 0 FidL-like putative membrane protein HAT_KAT11 PF08214.11 EGG01985.1 - 1.4e-26 93.6 0.1 6.6e-20 71.7 0.0 3.0 1 1 2 3 3 3 2 Histone acetylation protein Phage_CP76 PF06892.11 EGG01985.1 - 0.13 11.8 2.2 0.21 11.1 2.2 1.3 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) Pinin_SDK_memA PF04696.13 EGG01985.1 - 0.7 10.0 10.1 1.2 9.2 10.1 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Dynactin_p22 PF07426.11 EGG01989.1 - 0.064 13.1 0.2 0.081 12.8 0.2 1.1 1 0 0 1 1 1 0 Dynactin subunit p22 Tannase PF07519.11 EGG01990.1 - 1.1e-76 258.6 0.0 4.5e-56 190.7 0.0 2.4 2 1 0 2 2 2 2 Tannase and feruloyl esterase ThaI PF15514.6 EGG01990.1 - 0.093 12.4 0.0 5.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Restriction endonuclease ThaI CarbopepD_reg_2 PF13715.6 EGG01990.1 - 0.19 11.8 0.2 0.47 10.5 0.2 1.6 1 0 0 1 1 1 0 CarboxypepD_reg-like domain Tannase PF07519.11 EGG01991.1 - 1.4e-96 324.3 0.1 1.7e-96 324.0 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Retrotran_gag_3 PF14244.6 EGG01992.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Tricorn_PDZ PF14685.6 EGG01993.1 - 0.021 14.8 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain DUF1082 PF06449.11 EGG01993.1 - 0.17 11.7 1.5 24 4.9 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) zf-C3HC PF07967.13 EGG01994.1 - 5.2e-21 75.1 0.1 1.6e-17 63.8 0.1 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 EGG01994.1 - 1.3e-15 57.3 0.0 7.5e-10 38.8 0.0 3.1 2 2 0 2 2 2 2 Rsm1-like BIR PF00653.21 EGG01994.1 - 0.0027 18.3 0.1 0.14 12.9 0.0 2.9 3 0 0 3 3 3 1 Inhibitor of Apoptosis domain DUF4599 PF15371.6 EGG01994.1 - 0.29 11.7 4.1 8.8 6.9 0.5 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4599) BHD_3 PF10405.9 EGG01997.1 - 5.8e-24 84.3 0.0 1.3e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 EGG01997.1 - 7e-22 77.7 0.7 7e-22 77.7 0.7 2.3 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 EGG01997.1 - 1.9e-18 66.0 0.0 4.2e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EGG01997.1 - 8.7e-16 58.6 1.1 1.5e-14 54.7 0.1 3.6 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EGG01997.1 - 0.0052 17.2 0.0 0.026 15.0 0.0 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF4407 PF14362.6 EGG01998.1 - 0.14 11.5 1.6 0.18 11.1 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.10 EGG01998.1 - 0.8 10.0 14.6 1.2 9.5 14.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 EGG01998.1 - 2.8 6.1 9.4 3.4 5.9 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein ADIP PF11559.8 EGG01999.1 - 0.0095 16.0 0.8 0.014 15.5 0.8 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 EGG01999.1 - 0.038 13.3 3.4 0.042 13.2 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Spc19 PF08287.11 EGG01999.1 - 0.11 12.3 5.3 0.18 11.7 5.3 1.4 1 0 0 1 1 1 0 Spc19 ABC_tran_CTD PF16326.5 EGG01999.1 - 0.12 12.7 6.1 0.2 11.9 6.1 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain SKA1 PF07160.12 EGG01999.1 - 0.13 12.1 4.3 0.18 11.6 4.3 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Ax_dynein_light PF10211.9 EGG01999.1 - 0.28 11.1 3.7 0.37 10.7 3.7 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Vfa1 PF08432.10 EGG01999.1 - 0.46 10.8 17.0 0.7 10.2 17.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FlxA PF14282.6 EGG01999.1 - 1.5 8.9 9.6 0.19 11.7 4.7 2.2 1 1 1 2 2 2 0 FlxA-like protein CDC45 PF02724.14 EGG01999.1 - 1.8 6.8 8.7 2 6.6 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4337 PF14235.6 EGG01999.1 - 3.7 7.6 8.9 6 7.0 8.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Casc1 PF12366.8 EGG01999.1 - 6.5 6.2 8.1 9.7 5.6 8.1 1.3 1 1 0 1 1 1 0 Cancer susceptibility candidate 1 FAM76 PF16046.5 EGG01999.1 - 7.2 5.9 15.5 3.2 7.0 10.3 1.9 1 1 1 2 2 2 0 FAM76 protein Sde2_N_Ubi PF13019.6 EGG02000.1 - 1.3e-42 145.4 0.4 1.3e-42 145.4 0.4 1.8 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain DUF3450 PF11932.8 EGG02000.1 - 0.05 12.9 2.1 0.077 12.3 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SET PF00856.28 EGG02004.1 - 0.00034 21.1 0.0 0.00062 20.2 0.0 1.5 1 0 0 1 1 1 1 SET domain Mito_carr PF00153.27 EGG02005.1 - 3.8e-60 199.8 0.1 9e-19 67.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Exo5 PF09810.9 EGG02006.1 - 7.4e-47 160.6 0.4 1.8e-33 116.5 0.0 3.8 1 1 1 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease UIM PF02809.20 EGG02006.1 - 0.26 11.3 1.5 0.59 10.2 1.5 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif DnaJ PF00226.31 EGG02008.1 - 3.4e-09 36.7 3.9 3.8e-09 36.6 1.1 2.4 2 0 0 2 2 2 1 DnaJ domain DUF1351 PF07083.11 EGG02008.1 - 0.18 11.6 6.8 0.09 12.5 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) 4PPT_N PF17837.1 EGG02008.1 - 0.19 11.9 0.8 1 9.5 0.1 2.4 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain DUF573 PF04504.14 EGG02008.1 - 3.9 8.2 11.0 18 6.0 5.9 3.0 2 2 0 2 2 2 0 Protein of unknown function, DUF573 Rtf2 PF04641.12 EGG02009.1 - 1.1e-54 185.6 14.6 2.4e-54 184.4 14.6 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 EGG02009.1 - 7.4e-05 22.5 1.1 0.013 15.3 1.1 2.8 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EGG02009.1 - 0.00026 21.0 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DUF4927 PF16279.5 EGG02009.1 - 0.019 16.0 1.1 0.019 16.0 1.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4927) LMBR1 PF04791.16 EGG02009.1 - 1.1 8.1 2.2 1.3 7.8 2.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SAP PF02037.27 EGG02011.1 - 7.4e-05 22.4 2.4 7.4e-05 22.4 2.4 2.0 2 0 0 2 2 2 1 SAP domain ubiquitin PF00240.23 EGG02012.1 - 4e-26 90.6 1.3 4.5e-26 90.4 1.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGG02012.1 - 4.3e-15 55.3 1.2 4.8e-15 55.1 1.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGG02012.1 - 0.00028 21.2 0.4 0.00034 20.9 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGG02012.1 - 0.004 17.2 0.3 0.0065 16.6 0.3 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EGG02012.1 - 0.0071 16.3 0.0 0.0087 16.0 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EGG02012.1 - 0.013 15.9 0.2 0.016 15.7 0.2 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 EGG02012.1 - 0.021 15.4 0.1 0.023 15.2 0.1 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF5383 PF17355.2 EGG02012.1 - 0.082 13.3 0.4 0.1 13.0 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5383) GPI-anchored PF10342.9 EGG02013.1 - 4.6e-12 46.5 0.9 5.9e-12 46.2 0.9 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FAD_binding_8 PF08022.12 EGG02013.1 - 0.0043 17.1 0.0 0.009 16.1 0.0 1.6 1 1 0 1 1 1 1 FAD-binding domain Big_5 PF13205.6 EGG02013.1 - 0.0061 17.2 0.2 0.008 16.9 0.2 1.2 1 0 0 1 1 1 1 Bacterial Ig-like domain PNGaseA PF12222.8 EGG02014.1 - 2.7e-64 217.7 0.6 2.7e-64 217.7 0.6 2.0 2 1 0 2 2 2 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A AAA PF00004.29 EGG02015.1 - 8.5e-44 149.2 0.0 1.5e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG02015.1 - 8.9e-13 47.8 1.3 1.7e-12 46.9 0.2 2.0 2 0 0 2 2 2 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EGG02015.1 - 8e-11 41.7 0.1 1.7e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EGG02015.1 - 1.8e-07 31.7 0.1 0.0003 21.2 0.0 3.4 2 1 1 4 4 4 1 AAA ATPase domain AAA_2 PF07724.14 EGG02015.1 - 2.8e-07 30.8 0.0 1.9e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGG02015.1 - 1.2e-06 28.5 0.1 4.5e-05 23.5 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGG02015.1 - 4.3e-06 26.6 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGG02015.1 - 0.00015 22.0 0.1 0.0028 17.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGG02015.1 - 0.00022 20.5 0.0 0.00038 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 EGG02015.1 - 0.00056 19.5 0.0 0.0012 18.4 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EGG02015.1 - 0.00063 20.3 0.4 0.0076 16.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGG02015.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EGG02015.1 - 0.0018 17.7 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGG02015.1 - 0.002 17.9 0.1 0.0072 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGG02015.1 - 0.0027 18.1 0.0 0.0055 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EGG02015.1 - 0.0028 17.7 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGG02015.1 - 0.0036 17.0 0.0 0.0078 16.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 EGG02015.1 - 0.008 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EGG02015.1 - 0.0081 15.9 0.1 0.027 14.2 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.6 EGG02015.1 - 0.0087 16.2 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EGG02015.1 - 0.0095 15.8 0.1 0.034 14.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EGG02015.1 - 0.024 13.7 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 EGG02015.1 - 0.027 13.8 0.1 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 EGG02015.1 - 0.032 14.5 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 EGG02015.1 - 0.036 13.8 0.1 2.8 7.6 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase AAA_30 PF13604.6 EGG02015.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGG02015.1 - 0.061 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 EGG02015.1 - 0.068 13.1 0.0 0.22 11.4 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EGG02015.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 EGG02015.1 - 0.13 11.8 0.1 0.36 10.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGG02015.1 - 0.14 11.9 0.9 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGG02015.1 - 0.16 12.3 0.1 0.56 10.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Maf_N PF08383.11 EGG02016.1 - 0.019 14.7 11.3 4.3 7.2 0.3 4.5 2 2 3 5 5 5 0 Maf N-terminal region Ribosomal_L19e PF01280.20 EGG02017.1 - 1e-60 204.0 10.1 1e-60 204.0 10.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L19e OmdA PF13376.6 EGG02017.1 - 0.012 15.6 0.4 0.012 15.6 0.4 2.3 1 1 1 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated NIP_1 PF08995.10 EGG02018.1 - 0.046 14.1 1.2 0.067 13.6 1.2 1.3 1 0 0 1 1 1 0 Necrosis inducing protein-1 PITH PF06201.13 EGG02019.1 - 9.9e-29 100.5 0.0 2.7e-28 99.1 0.0 1.6 1 1 0 1 1 1 1 PITH domain Peroxin-13_N PF04088.13 EGG02021.1 - 5.4e-39 133.8 1.1 5.4e-39 133.8 1.1 1.6 2 0 0 2 2 2 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EGG02021.1 - 1.2e-10 40.9 0.1 3.6e-10 39.4 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGG02021.1 - 1.3e-09 37.5 0.1 2.7e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGG02021.1 - 6.7e-09 35.5 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.14 EGG02021.1 - 0.059 12.9 0.2 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region RRF PF01765.19 EGG02021.1 - 0.13 12.2 2.4 3.4 7.6 0.2 2.2 2 0 0 2 2 2 0 Ribosome recycling factor Keratin_2_head PF16208.5 EGG02021.1 - 2.4 8.3 27.7 5 7.2 27.7 1.5 1 0 0 1 1 1 0 Keratin type II head RNA_pol_Rpb1_2 PF00623.20 EGG02023.1 - 0.00045 20.5 0.0 0.00051 20.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 CAF1A PF12253.8 EGG02024.1 - 0.018 15.2 0.7 0.022 14.9 0.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A 3HCDH_N PF02737.18 EGG02024.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_9 PF12781.7 EGG02025.1 - 6.1e-08 32.1 0.0 8.9e-08 31.5 0.0 1.5 1 1 0 1 1 1 1 ATP-binding dynein motor region PLN_propep PF16485.5 EGG02025.1 - 0.038 13.7 0.1 0.087 12.6 0.1 1.5 1 0 0 1 1 1 0 Protealysin propeptide AAA_5 PF07728.14 EGG02025.1 - 0.073 13.1 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF948 PF06103.11 EGG02026.1 - 0.04 14.2 3.0 0.071 13.4 2.0 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Vac_Fusion PF02346.16 EGG02026.1 - 0.19 11.4 2.1 0.62 9.7 0.5 2.5 2 1 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 CLZ PF16526.5 EGG02026.1 - 0.61 10.5 11.5 0.06 13.7 2.4 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 EGG02026.1 - 1 9.5 8.2 0.36 11.0 1.1 2.5 2 0 0 2 2 2 0 bZIP transcription factor SpecificRecomb PF10136.9 EGG02026.1 - 1.1 7.5 3.2 1.4 7.1 3.2 1.1 1 0 0 1 1 1 0 Site-specific recombinase CRR7 PF12095.8 EGG02026.1 - 3.4 8.2 7.1 3.3 8.2 3.5 2.3 1 1 1 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 GBP_C PF02841.14 EGG02026.1 - 3.8 6.8 11.7 5.9 6.2 11.7 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF16 PF01519.16 EGG02026.1 - 4.3 7.9 10.5 28 5.3 8.3 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF2802 PF10975.8 EGG02026.1 - 6.9 6.9 7.1 8.9 6.5 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) CCDC-167 PF15188.6 EGG02029.1 - 0.038 14.3 0.1 0.093 13.1 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 TPR_9 PF13371.6 EGG02029.1 - 0.076 13.2 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2605 PF10792.9 EGG02029.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) TPR_19 PF14559.6 EGG02036.1 - 1.5e-06 28.6 0.2 0.025 15.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG02036.1 - 0.0011 18.9 3.0 4 7.9 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG02036.1 - 0.0035 17.5 0.5 6 7.2 0.0 3.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGG02036.1 - 0.0047 17.2 2.3 3.9 7.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG02036.1 - 0.031 15.1 0.3 13 6.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG02036.1 - 0.04 14.6 7.5 3.3 8.5 0.2 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Complex1_LYR_2 PF13233.6 EGG02036.1 - 0.14 12.9 3.5 1.9 9.3 0.0 2.6 2 1 0 2 2 2 0 Complex1_LYR-like AMP-binding PF00501.28 EGG02037.1 - 8.7e-72 242.0 0.0 1e-71 241.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG02037.1 - 1.5e-13 51.5 0.0 5.1e-13 49.8 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cuticle_1 PF08140.11 EGG02037.1 - 0.029 14.4 0.2 3.4 7.8 0.1 2.7 2 0 0 2 2 2 0 Crustacean cuticle protein repeat MgtE_N PF03448.17 EGG02038.1 - 0.094 13.3 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain DUF4663 PF15668.5 EGG02039.1 - 0.14 11.2 0.7 0.17 10.9 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) DUF285 PF03382.14 EGG02039.1 - 0.16 11.8 0.1 0.2 11.4 0.1 1.1 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 Aha1_N PF09229.11 EGG02040.1 - 4.5e-23 82.0 0.2 6.5e-23 81.4 0.2 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EGG02040.1 - 1e-13 51.6 0.1 3.4e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Glyco_transf_43 PF03360.16 EGG02041.1 - 0.0016 18.3 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 43 Glyco_transf_43 PF03360.16 EGG02042.1 - 0.0065 16.3 0.0 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 43 IF-2B PF01008.17 EGG02043.1 - 3.9e-59 200.2 0.0 4.4e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF656 PF04920.12 EGG02043.1 - 0.039 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF656) DUF3429 PF11911.8 EGG02044.1 - 9.4e-44 149.2 9.2 1.2e-43 148.9 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) zf-C2H2 PF00096.26 EGG02045.1 - 2.7e-10 40.1 10.6 5.2e-06 26.6 3.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG02045.1 - 8.4e-08 32.3 0.8 8.4e-08 32.3 0.8 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG02045.1 - 2.4e-06 27.9 9.3 0.00074 20.1 2.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf_ZIC PF18366.1 EGG02045.1 - 2.4e-05 24.4 1.2 0.041 14.0 0.1 2.1 2 0 0 2 2 2 2 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 EGG02045.1 - 5e-05 23.5 8.4 0.013 15.8 0.8 2.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG02045.1 - 0.0033 17.7 5.8 0.73 10.3 0.5 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 EGG02045.1 - 0.013 16.1 1.5 0.024 15.3 0.2 1.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 EGG02045.1 - 2.6 7.9 8.2 5 7.0 0.0 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 EGG02045.1 - 3.3 7.8 7.6 14 5.8 0.2 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger CxC1 PF18802.1 EGG02049.1 - 2.9e-31 107.7 0.2 6.1e-31 106.7 0.2 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG02049.1 - 1.4e-10 41.3 0.2 3.3e-10 40.1 0.2 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG02049.1 - 0.00094 19.0 0.1 0.0021 17.9 0.1 1.6 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases Choline_kinase PF01633.20 EGG02050.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase NUDIX PF00293.28 EGG02051.1 - 3.2e-14 53.1 0.0 6.1e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SR-25 PF10500.9 EGG02051.1 - 0.028 14.0 7.4 0.057 13.0 7.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PKHD_C PF18331.1 EGG02051.1 - 0.46 10.6 2.0 5.8 7.1 1.2 2.4 1 1 1 2 2 2 0 PKHD-type hydroxylase C-terminal domain COesterase PF00135.28 EGG02052.1 - 2e-81 274.4 0.0 2.5e-81 274.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG02052.1 - 2.3e-08 34.2 0.4 2.8e-07 30.6 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG02052.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family UK PF02512.14 EGG02052.1 - 0.067 13.7 0.0 26 5.4 0.0 2.6 2 0 0 2 2 2 0 Virulence determinant Syntaxin-18_N PF10496.9 EGG02053.1 - 3.2e-15 56.1 1.7 3.2e-15 56.1 1.7 2.8 4 0 0 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 EGG02053.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 SNARE domain Mnd1 PF03962.15 EGG02053.1 - 0.13 12.6 0.1 3.5 8.0 0.0 2.7 3 0 0 3 3 3 0 Mnd1 HTH domain DUF929 PF06053.11 EGG02054.1 - 0.0056 16.0 1.7 0.94 8.7 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF929) TPP_enzyme_N PF02776.18 EGG02055.1 - 4.4e-54 182.7 0.0 9.1e-54 181.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGG02055.1 - 1.1e-45 155.2 0.0 1.5e-44 151.4 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGG02055.1 - 1.6e-40 138.0 0.1 4.2e-40 136.6 0.1 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain PFU PF09070.11 EGG02056.1 - 7.7e-41 138.9 0.2 1.4e-40 138.1 0.2 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EGG02056.1 - 1.1e-27 95.7 9.4 5e-08 33.5 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat FBPase PF00316.20 EGG02057.1 - 3.6e-75 251.6 0.0 4.8e-75 251.2 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 EGG02057.1 - 0.018 14.5 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Inositol monophosphatase family AceK PF06315.11 EGG02058.1 - 0.11 10.9 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) ABC_tran PF00005.27 EGG02059.1 - 0.076 13.5 0.3 0.14 12.7 0.3 1.3 1 0 0 1 1 1 0 ABC transporter Pneumo_att_G PF05539.11 EGG02059.1 - 0.2 11.2 12.9 0.31 10.6 12.9 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SET PF00856.28 EGG02061.1 - 0.00055 20.4 0.3 0.024 15.0 0.0 2.8 3 1 0 3 3 3 1 SET domain SH3_9 PF14604.6 EGG02062.1 - 1.7e-05 24.6 0.1 4.7e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 Variant SH3 domain DUF4448 PF14610.6 EGG02062.1 - 0.04 13.7 0.1 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) SH3_1 PF00018.28 EGG02062.1 - 0.19 11.4 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 SH3 domain DUF2371 PF10177.9 EGG02062.1 - 0.57 10.3 0.0 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) PAT1 PF09770.9 EGG02062.1 - 6.7 4.8 29.2 12 4.0 29.2 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MRP-L20 PF12824.7 EGG02065.1 - 9.2e-12 45.4 0.7 1.4e-11 44.9 0.7 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.12 EGG02065.1 - 0.029 14.3 0.2 0.085 12.8 0.1 1.7 2 0 0 2 2 2 0 HTH domain Mem_trans PF03547.18 EGG02066.1 - 3.3e-36 124.5 2.4 4.8e-36 124.0 2.4 1.1 1 0 0 1 1 1 1 Membrane transport protein DUF4064 PF13273.6 EGG02066.1 - 0.029 14.6 0.7 0.029 14.6 0.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) RRM_1 PF00076.22 EGG02068.1 - 9.3e-11 41.4 0.1 8.9e-10 38.3 0.1 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG02068.1 - 0.0097 16.0 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif TauD PF02668.16 EGG02069.1 - 5.5e-45 154.2 0.3 1e-44 153.4 0.3 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HCNGP PF07818.13 EGG02069.1 - 0.00031 21.3 2.3 0.24 12.1 0.1 3.1 2 0 0 2 2 2 2 HCNGP-like protein DUF971 PF06155.12 EGG02069.1 - 0.0044 17.6 0.4 0.017 15.7 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF971) TAF4 PF05236.14 EGG02071.1 - 0.17 11.6 13.6 0.24 11.1 13.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RR_TM4-6 PF06459.12 EGG02071.1 - 0.61 9.9 8.9 0.82 9.4 8.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3464 PF11947.8 EGG02071.1 - 7.2 6.3 9.6 13 5.5 9.6 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Sec62 PF03839.16 EGG02071.1 - 9.7 5.6 12.3 15 5.1 12.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 PRP38 PF03371.15 EGG02072.1 - 1.1e-56 191.5 0.7 1.3e-56 191.2 0.7 1.0 1 0 0 1 1 1 1 PRP38 family Mit_ribos_Mrp51 PF11709.8 EGG02073.1 - 7.2e-23 81.8 0.3 1.1e-22 81.1 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit BolA PF01722.18 EGG02074.1 - 4.9e-27 94.0 0.5 5.6e-27 93.8 0.5 1.0 1 0 0 1 1 1 1 BolA-like protein PQ-loop PF04193.14 EGG02075.1 - 1.3e-18 66.4 18.0 5e-09 35.8 6.3 2.9 2 0 0 2 2 2 2 PQ loop repeat CwfJ_C_2 PF04676.14 EGG02079.1 - 2.3e-34 118.2 0.0 8.1e-34 116.5 0.0 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EGG02079.1 - 4e-27 94.5 0.0 7e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RhoGAP PF00620.27 EGG02080.1 - 3.6e-20 72.4 0.0 2.1e-19 69.8 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain DUF1104 PF06518.11 EGG02080.1 - 5.5 7.4 5.9 4.1 7.8 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) zf-C2H2 PF00096.26 EGG02081.1 - 6.9e-21 73.5 30.1 1.3e-05 25.4 0.7 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG02081.1 - 6.9e-21 73.7 29.0 6.2e-08 32.7 0.1 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG02081.1 - 1.4e-12 47.3 27.9 0.0023 18.6 0.9 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGG02081.1 - 0.00072 19.8 6.5 0.36 11.2 0.0 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 EGG02081.1 - 0.0016 18.7 8.8 0.084 13.2 4.8 3.3 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 EGG02081.1 - 0.0035 17.1 0.9 0.0035 17.1 0.9 3.3 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 EGG02081.1 - 0.017 15.0 0.8 0.054 13.4 0.3 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.7 EGG02081.1 - 0.02 15.3 13.9 2 8.9 0.2 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 EGG02081.1 - 0.14 12.9 13.6 0.071 13.8 2.6 2.6 1 1 2 3 3 3 0 TRAF-type zinc finger zf-H2C2_5 PF13909.6 EGG02081.1 - 0.31 10.8 0.1 0.31 10.8 0.1 5.5 6 1 0 6 6 6 0 C2H2-type zinc-finger domain UCR_14kD PF02271.16 EGG02082.1 - 3e-43 145.9 1.6 3.5e-43 145.6 1.6 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF1845 PF08900.11 EGG02082.1 - 0.061 13.1 0.1 0.077 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) Acyltransferase PF01553.21 EGG02083.1 - 3.6e-12 46.1 0.0 5.5e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase DUF1460 PF07313.12 EGG02083.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) DUF5619 PF18505.1 EGG02084.1 - 0.19 11.8 0.0 0.87 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5619) LRR19-TM PF15176.6 EGG02088.1 - 0.49 10.4 3.3 1.3 9.0 1.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF3195 PF11424.8 EGG02093.1 - 0.1 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGG02093.1 - 0.15 11.0 0.4 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 NUC194 domain DUF2170 PF09938.9 EGG02093.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) GlcNAc-1_reg PF18440.1 EGG02096.1 - 0.15 12.3 0.0 0.19 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain DUF4616 PF15394.6 EGG02097.1 - 0.0037 16.3 0.4 0.0037 16.3 0.4 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4616) VID27 PF08553.10 EGG02097.1 - 0.019 14.1 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain N2227 PF07942.12 EGG02098.1 - 1.7e-21 76.7 0.0 1.9e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein TPMT PF05724.11 EGG02098.1 - 0.031 13.9 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Hid1 PF12722.7 EGG02100.1 - 2 6.4 8.7 2.4 6.2 8.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MutS_I PF01624.20 EGG02101.1 - 0.015 15.5 0.1 0.093 13.0 0.0 2.1 2 0 0 2 2 2 0 MutS domain I Cwf_Cwc_15 PF04889.12 EGG02101.1 - 2.7 7.6 23.5 1.6 8.4 21.2 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TFIIA_gamma_N PF02268.16 EGG02104.1 - 0.053 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Pam17 PF08566.10 EGG02105.1 - 1.1e-48 165.2 0.0 1.3e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Aph-1 PF06105.12 EGG02105.1 - 0.077 12.4 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Aph-1 protein Peptidase_M41 PF01434.18 EGG02106.1 - 8.2e-55 185.6 0.1 1.6e-54 184.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGG02106.1 - 9.5e-42 142.6 0.0 3.8e-41 140.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG02106.1 - 4.8e-12 45.5 0.0 1.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGG02106.1 - 8.4e-06 26.3 5.3 8.8e-05 22.9 1.1 3.7 2 2 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGG02106.1 - 3.4e-05 23.6 0.0 8.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGG02106.1 - 0.00046 20.2 0.0 0.0013 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGG02106.1 - 0.00055 19.2 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EGG02106.1 - 0.0012 19.1 6.0 0.032 14.5 0.1 3.9 4 1 1 5 5 5 1 AAA domain AAA_33 PF13671.6 EGG02106.1 - 0.0033 17.6 0.0 0.0099 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG02106.1 - 0.011 16.3 0.0 0.029 14.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGG02106.1 - 0.015 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGG02106.1 - 0.024 14.0 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGG02106.1 - 0.03 14.6 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGG02106.1 - 0.035 14.1 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 EGG02106.1 - 0.071 13.2 0.0 0.29 11.2 0.0 2.1 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_2 PF07724.14 EGG02106.1 - 0.077 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF3687 PF12459.8 EGG02106.1 - 0.081 12.5 0.4 0.16 11.5 0.4 1.4 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein ATPase PF06745.13 EGG02106.1 - 0.084 12.2 2.4 0.33 10.3 0.1 2.4 2 1 1 3 3 3 0 KaiC AAA_25 PF13481.6 EGG02106.1 - 0.21 11.1 3.7 0.45 10.1 0.2 2.7 2 1 1 3 3 3 0 AAA domain NACHT PF05729.12 EGG02106.1 - 0.56 10.1 3.2 1.2 9.0 0.2 2.8 3 0 0 3 3 3 0 NACHT domain zf-RING_2 PF13639.6 EGG02107.1 - 5.2e-07 29.9 9.2 7.5e-07 29.4 9.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EGG02107.1 - 0.002 18.1 5.1 0.0035 17.3 5.1 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EGG02107.1 - 0.0045 17.1 6.4 0.011 15.9 6.4 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain C1_1 PF00130.22 EGG02107.1 - 0.0074 16.1 2.1 0.0074 16.1 2.1 2.0 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.7 EGG02107.1 - 0.0095 16.2 12.4 0.034 14.4 12.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGG02107.1 - 0.017 15.0 8.3 0.03 14.2 8.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EGG02107.1 - 0.018 15.4 7.6 0.048 14.0 7.6 1.7 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.7 EGG02107.1 - 0.066 13.3 7.2 0.18 11.9 7.3 1.7 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 EGG02107.1 - 0.076 12.6 6.3 0.14 11.8 6.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EGG02107.1 - 0.092 12.6 10.2 0.3 11.0 10.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EGG02107.1 - 0.57 10.1 6.6 1.2 9.1 6.6 1.7 1 1 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 EGG02107.1 - 2.9 7.8 6.6 27 4.7 6.8 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD_4 PF16866.5 EGG02107.1 - 3.3 7.9 6.8 12 6.1 4.2 2.4 2 1 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 EGG02107.1 - 3.9 7.7 7.9 13 6.0 7.1 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger IF-2B PF01008.17 EGG02109.1 - 0.031 13.5 0.0 0.031 13.5 0.0 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family Ribosomal_L24e PF01246.20 EGG02110.1 - 1.1e-33 115.3 7.3 2.6e-33 114.1 7.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e HlyIII PF03006.20 EGG02111.1 - 2.2e-54 184.5 17.1 2.8e-54 184.2 17.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ribosomal_L13 PF00572.18 EGG02112.1 - 1.8e-36 125.1 0.0 2e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 DUF3018 PF11455.8 EGG02113.1 - 2.9 7.9 0.0 2.9 7.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3018) SPX PF03105.19 EGG02114.1 - 0.16 11.8 2.9 0.18 11.7 2.9 1.1 1 0 0 1 1 1 0 SPX domain VPDSG-CTERM PF18205.1 EGG02115.1 - 0.06 13.2 1.6 0.13 12.1 1.6 1.6 1 0 0 1 1 1 0 VPDSG-CTERM motif DUF202 PF02656.15 EGG02117.1 - 0.0042 17.5 3.5 0.017 15.6 3.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF202) DUF4079 PF13301.6 EGG02117.1 - 0.02 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) PAP2_C PF14360.6 EGG02117.1 - 0.2 12.2 3.2 0.8 10.3 0.2 2.1 2 0 0 2 2 2 0 PAP2 superfamily C-terminal VPDSG-CTERM PF18205.1 EGG02117.1 - 0.25 11.2 0.3 0.25 11.2 0.3 2.2 3 0 0 3 3 3 0 VPDSG-CTERM motif ATP-synt_8 PF00895.20 EGG02117.1 - 4.3 7.9 0.0 4.3 7.9 0.0 2.9 3 0 0 3 3 3 0 ATP synthase protein 8 Pro_isomerase PF00160.21 EGG02120.1 - 3.2e-52 177.0 0.0 3.6e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cyclin_N PF00134.23 EGG02121.1 - 1.7e-15 56.9 0.1 3.4e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGG02121.1 - 0.0002 21.4 2.3 0.031 14.4 0.2 2.8 2 1 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 EGG02121.1 - 0.036 14.4 2.1 0.19 12.2 0.2 2.4 1 1 0 2 2 2 0 Cyclin C-terminal domain TFIIB PF00382.19 EGG02121.1 - 0.14 12.2 0.5 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 Transcription factor TFIIB repeat FUSC_2 PF13515.6 EGG02122.1 - 7.9e-21 74.5 12.2 7.9e-21 74.5 12.2 2.9 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 EGG02122.1 - 6.7e-12 45.0 7.1 8.8e-12 44.6 5.3 1.9 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC PF04632.12 EGG02122.1 - 6.9e-12 44.7 20.4 2.4e-11 43.0 3.5 4.3 4 1 0 4 4 4 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 EGG02122.1 - 2.7e-09 37.2 1.5 1.2e-08 35.1 0.2 2.5 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 SWIM PF04434.17 EGG02123.1 - 2.2e-07 30.4 0.1 4.7e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger PHD PF00628.29 EGG02123.1 - 0.00081 19.2 9.1 0.0019 18.0 9.1 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 EGG02123.1 - 0.0024 18.2 8.0 0.0024 18.2 8.0 1.8 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 EGG02123.1 - 0.049 13.8 7.7 0.087 13.0 5.3 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain SWIM PF04434.17 EGG02124.1 - 9e-08 31.6 0.1 1.9e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_2 PF13639.6 EGG02124.1 - 0.00011 22.4 7.3 0.00011 22.4 7.3 1.9 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.29 EGG02124.1 - 0.014 15.3 8.0 0.029 14.3 8.0 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 EGG02124.1 - 0.014 15.5 5.0 0.014 15.5 5.0 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain NSP10 PF09401.10 EGG02124.1 - 0.015 15.4 0.8 0.027 14.5 0.8 1.4 1 0 0 1 1 1 0 RNA synthesis protein NSP10 AGA2 PF17366.2 EGG02124.1 - 0.064 13.0 0.3 0.17 11.6 0.2 1.7 2 0 0 2 2 2 0 A-agglutinin-binding subunit Aga2 Glyco_hydro_36 PF17167.4 EGG02124.1 - 0.15 10.7 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain zf-ANAPC11 PF12861.7 EGG02124.1 - 0.27 11.3 4.5 0.99 9.5 4.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGG02124.1 - 5.4 7.1 14.1 0.3 11.1 8.8 1.7 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 EGG02124.1 - 6.2 7.2 9.3 2.6 8.4 6.3 2.1 2 1 0 2 2 2 0 RING-like domain SWIM PF04434.17 EGG02125.1 - 3.1e-06 26.7 0.1 6.2e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_2 PF13639.6 EGG02125.1 - 0.00091 19.5 7.2 0.0026 18.0 7.2 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.6 EGG02125.1 - 0.0015 18.4 4.5 0.0015 18.4 4.5 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 PHD PF00628.29 EGG02125.1 - 0.0025 17.7 8.8 0.0049 16.7 8.8 1.5 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.8 EGG02125.1 - 0.012 15.8 4.7 0.028 14.6 4.7 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain OrfB_Zn_ribbon PF07282.11 EGG02125.1 - 0.34 10.9 2.2 0.83 9.6 0.5 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-RING_5 PF14634.6 EGG02125.1 - 2.1 8.4 7.1 4.8 7.2 7.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Sgf11_N PF18519.1 EGG02126.1 - 0.066 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 SAGA-associated factor 11 N-terminal domain PHD PF00628.29 EGG02127.1 - 1.4e-10 40.9 8.2 1.8e-10 40.5 1.2 2.0 1 1 1 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 EGG02127.1 - 0.026 14.1 1.8 0.026 14.1 1.8 1.5 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 EGG02127.1 - 0.078 13.3 9.8 0.11 12.8 9.8 1.4 1 1 0 1 1 1 0 C1 domain C1_1 PF00130.22 EGG02127.1 - 0.27 11.1 7.9 0.63 10.0 7.9 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MOZ_SAS PF01853.18 EGG02128.1 - 9.9e-70 233.8 0.1 1.3e-69 233.4 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGG02128.1 - 2e-19 68.9 6.0 2e-19 68.9 6.0 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain zf-met PF12874.7 EGG02128.1 - 0.031 14.7 2.6 0.068 13.6 2.6 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DPBB_1 PF03330.18 EGG02130.1 - 8.4e-10 38.8 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EGG02130.1 - 0.016 15.0 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Barwin family DZR PF12773.7 EGG02130.1 - 0.041 13.9 0.6 0.1 12.6 0.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EGG02130.1 - 0.22 11.0 2.8 0.89 9.1 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 EGG02130.1 - 3.1 7.7 6.7 15 5.5 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Glyco_hydro_47 PF01532.20 EGG02131.1 - 5.7e-93 312.3 0.0 1.7e-92 310.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PTPLA PF04387.14 EGG02132.1 - 9.9e-41 139.2 6.7 1.2e-40 139.0 6.7 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Sarcoglycan_2 PF05510.13 EGG02132.1 - 0.085 11.6 0.3 0.1 11.4 0.3 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon WD40 PF00400.32 EGG02133.1 - 5.3e-25 87.2 14.5 2.4e-08 34.5 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG02133.1 - 1.4e-07 31.7 0.0 0.0074 16.6 0.0 4.5 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG02133.1 - 0.017 14.1 0.0 0.039 12.9 0.0 1.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGG02133.1 - 0.029 13.1 0.0 0.85 8.3 0.0 2.3 2 1 0 2 2 2 0 Nup133 N terminal like PQQ_3 PF13570.6 EGG02133.1 - 0.031 14.7 0.0 11 6.6 0.0 4.3 4 1 0 4 4 4 0 PQQ-like domain zf-C2H2 PF00096.26 EGG02134.1 - 1.5e-19 69.3 21.0 6.7e-07 29.4 0.2 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG02134.1 - 2.7e-18 65.5 17.9 3.5e-07 30.4 0.1 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG02134.1 - 2e-10 40.6 18.3 0.00064 20.3 0.2 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EGG02134.1 - 0.00017 21.8 5.8 0.0026 18.0 0.5 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 EGG02134.1 - 0.0062 16.8 8.9 0.14 12.5 0.4 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 EGG02134.1 - 0.0067 17.1 0.9 0.0067 17.1 0.9 2.3 1 1 1 2 2 2 2 TRAF-type zinc finger FOXP-CC PF16159.5 EGG02134.1 - 0.017 15.7 3.7 0.97 10.1 0.9 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EGG02134.1 - 0.038 14.0 10.6 1.2 9.2 0.1 4.4 4 2 0 4 4 4 0 C2H2-type zinc finger zf-CGNR PF11706.8 EGG02134.1 - 0.23 11.3 10.2 6.9 6.6 2.3 3.8 3 1 0 3 3 3 0 CGNR zinc finger zf-C2H2_aberr PF17017.5 EGG02134.1 - 1 9.5 8.9 4.9 7.3 0.1 3.3 1 1 2 3 3 3 0 Aberrant zinc-finger FANCL_C PF11793.8 EGG02134.1 - 2.3 8.5 6.9 3.2 8.0 2.4 2.6 1 1 2 3 3 3 0 FANCL C-terminal domain zf-C2H2_11 PF16622.5 EGG02134.1 - 2.8 7.8 11.2 0.27 11.0 2.2 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type Pyr_excise PF03013.14 EGG02135.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.5 1 1 0 1 1 1 0 Pyrimidine dimer DNA glycosylase MAPEG PF01124.18 EGG02136.1 - 7e-24 84.2 2.3 8.2e-24 84.0 2.3 1.0 1 0 0 1 1 1 1 MAPEG family Adap_comp_sub PF00928.21 EGG02137.1 - 2.7e-87 292.5 0.2 3.4e-87 292.2 0.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGG02137.1 - 6.4e-07 29.4 0.5 1.1e-06 28.6 0.5 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EGG02137.1 - 0.0048 16.4 0.2 0.0095 15.4 0.2 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Syja_N PF02383.18 EGG02138.1 - 2.9e-71 240.4 0.0 4e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Ytp1 PF10355.9 EGG02139.1 - 2.9e-37 128.4 23.4 5.3e-36 124.3 19.3 2.9 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EGG02139.1 - 2.2e-15 56.3 4.7 2.2e-15 56.3 4.7 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 EGG02139.1 - 8.3e-06 26.0 5.2 8.3e-06 26.0 5.2 3.1 3 1 0 3 3 3 1 Eukaryotic cytochrome b561 Sedlin_N PF04628.13 EGG02140.1 - 1e-30 106.5 0.8 1.9e-26 92.8 0.1 2.2 1 1 0 2 2 2 2 Sedlin, N-terminal conserved region Sybindin PF04099.12 EGG02140.1 - 4e-06 26.8 0.1 1e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 Sybindin-like family HMG_box PF00505.19 EGG02141.1 - 0.0044 17.4 0.1 0.013 15.9 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGG02141.1 - 0.0074 16.9 2.2 0.0095 16.5 0.2 2.0 2 0 0 2 2 2 1 HMG-box domain Rieske_3 PF18465.1 EGG02142.1 - 0.14 12.4 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Rieske 3Fe-4S Aminotran_5 PF00266.19 EGG02143.1 - 3.6e-33 115.0 0.0 1.4e-22 80.2 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V RhoGEF PF00621.20 EGG02144.1 - 9.4e-24 84.6 0.0 2.8e-23 83.1 0.0 1.8 1 1 1 2 2 2 1 RhoGEF domain FYVE PF01363.21 EGG02144.1 - 1.4e-18 66.8 12.3 2.8e-18 65.8 12.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 EGG02144.1 - 1.8e-05 25.2 0.1 0.00042 20.8 0.1 2.9 1 1 0 1 1 1 1 PH domain PH_13 PF16652.5 EGG02144.1 - 0.0029 17.4 0.5 0.67 9.8 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain Phage_RpbA PF10789.9 EGG02144.1 - 0.065 13.3 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA LRR_4 PF12799.7 EGG02145.1 - 7.5e-09 35.7 30.1 0.001 19.4 0.1 7.3 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGG02145.1 - 2.5e-05 24.0 12.2 2 8.7 0.1 7.5 9 0 0 9 9 9 3 Leucine Rich repeat STAS_2 PF13466.6 EGG02145.1 - 0.069 13.5 0.1 0.38 11.1 0.0 2.2 3 0 0 3 3 3 0 STAS domain LRR_8 PF13855.6 EGG02145.1 - 4.3 7.2 13.9 2 8.3 0.2 5.5 5 2 1 6 6 6 0 Leucine rich repeat DnaJ PF00226.31 EGG02146.1 - 5.1e-20 71.4 3.7 7.8e-20 70.8 1.3 2.6 2 0 0 2 2 2 1 DnaJ domain GSCFA PF08885.11 EGG02149.1 - 0.043 13.5 0.5 3.5 7.2 0.1 2.2 1 1 1 2 2 2 0 GSCFA family Sad1_UNC PF07738.13 EGG02150.1 - 2.3e-28 98.8 0.0 3.5e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal WD40 PF00400.32 EGG02163.1 - 4.2e-19 68.5 14.8 2.6e-06 28.1 0.3 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat CRAL_TRIO PF00650.20 EGG02165.1 - 0.066 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain RuBisCO_large PF00016.20 EGG02166.1 - 0.059 12.5 0.1 0.068 12.4 0.1 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Fib_alpha PF08702.10 EGG02167.1 - 0.019 15.1 0.6 0.025 14.7 0.6 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 EGG02167.1 - 0.036 14.4 0.3 0.079 13.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Streptin-Immun PF11083.8 EGG02167.1 - 0.11 12.9 0.6 1.7 9.1 0.1 2.1 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein TRI9 PF08195.11 EGG02170.1 - 0.15 11.9 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 TRI9 protein Nas2_N PF18265.1 EGG02174.1 - 6.3e-19 67.7 0.5 1.1e-18 66.9 0.5 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EGG02174.1 - 9.6e-05 22.1 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EGG02174.1 - 0.00034 20.9 0.1 0.00079 19.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGG02174.1 - 0.0031 17.8 0.0 0.0065 16.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Spore_GerAC PF05504.11 EGG02175.1 - 0.15 12.3 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal NAM-associated PF14303.6 EGG02175.1 - 0.46 11.2 4.1 0.63 10.7 4.1 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Ferlin_C PF16165.5 EGG02177.1 - 0.081 12.9 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 Ferlin C-terminus DUF4889 PF16230.5 EGG02179.1 - 0.14 12.4 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) DUF5383 PF17355.2 EGG02180.1 - 0.1 13.0 2.6 17 5.8 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5383) FLILHELTA PF10306.9 EGG02180.1 - 0.15 12.5 0.8 0.44 11.0 0.1 2.1 2 0 0 2 2 2 0 Hypothetical protein FLILHELTA SDA1 PF05285.12 EGG02181.1 - 0.41 10.0 16.6 0.57 9.5 16.6 1.2 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 EGG02181.1 - 1.4 9.4 31.9 1.8 9.0 21.3 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BUD22 PF09073.10 EGG02181.1 - 8.1 5.7 17.7 13 5.0 17.7 1.3 1 0 0 1 1 1 0 BUD22 TraI_2_C PF07515.11 EGG02183.1 - 0.0019 18.2 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 Putative conjugal transfer nickase/helicase TraI C-term DUF2194 PF09960.9 EGG02183.1 - 0.014 13.8 0.1 0.018 13.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) NST1 PF13945.6 EGG02183.1 - 0.016 15.3 4.1 0.026 14.7 4.1 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Ndc1_Nup PF09531.10 EGG02183.1 - 0.047 12.4 1.5 0.07 11.8 1.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glyco_hydro_42M PF08532.10 EGG02183.1 - 0.13 11.8 0.0 0.56 9.7 0.0 1.9 1 1 0 1 1 1 0 Beta-galactosidase trimerisation domain LYRIC PF15686.5 EGG02183.1 - 0.49 9.9 9.4 0.73 9.3 9.4 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Coilin_N PF15862.5 EGG02183.1 - 0.61 9.9 6.5 1.2 8.9 6.5 1.5 1 0 0 1 1 1 0 Coilin N-terminus AKAP2_C PF15304.6 EGG02183.1 - 1.2 8.4 9.1 1.9 7.7 9.1 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Tim54 PF11711.8 EGG02183.1 - 3.4 6.3 5.9 5.2 5.8 5.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 EGG02183.1 - 6.4 7.2 10.9 14 6.1 10.9 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2456 PF10445.9 EGG02184.1 - 2.3e-21 75.7 4.6 4.5e-21 74.7 4.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) DUF4395 PF14340.6 EGG02184.1 - 0.049 14.0 0.8 0.2 12.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) Ustilago_mating PF05722.12 EGG02186.1 - 0.00036 20.1 3.2 0.00055 19.6 3.2 1.2 1 0 0 1 1 1 1 Ustilago B locus mating-type protein Cohesin_HEAT PF12765.7 EGG02188.1 - 0.02 15.2 0.1 0.052 13.9 0.1 1.7 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion DUF3752 PF12572.8 EGG02189.1 - 2.4e-26 93.1 14.7 4.2e-14 53.3 0.6 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3752) PUF PF00806.19 EGG02190.1 - 5.3e-64 208.5 7.2 4.9e-09 35.4 0.1 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EGG02190.1 - 0.0014 19.0 0.2 26 5.2 0.0 4.3 2 2 2 4 4 4 1 CPL (NUC119) domain DUF3683 PF12447.8 EGG02190.1 - 0.12 12.5 0.1 0.54 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) DnaB_bind PF10410.9 EGG02190.1 - 0.14 12.3 0.1 7.2 6.9 0.0 2.8 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase Drf_GBD PF06371.13 EGG02192.1 - 0.029 13.9 0.1 0.041 13.4 0.1 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain DUF4763 PF15960.5 EGG02194.1 - 0.35 10.1 8.6 0.099 11.9 4.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) ATG22 PF11700.8 EGG02195.1 - 1.4e-114 383.4 19.8 3.4e-114 382.1 19.8 1.7 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EGG02195.1 - 8.8e-07 28.2 5.1 8.8e-07 28.2 5.1 4.4 3 2 1 4 4 4 3 Major Facilitator Superfamily Pam17 PF08566.10 EGG02195.1 - 0.14 12.0 0.2 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 SDA1 PF05285.12 EGG02198.1 - 5.6e-89 299.0 33.3 5.6e-89 299.0 33.3 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 EGG02198.1 - 5.7e-18 65.0 0.2 1.8e-17 63.4 0.2 1.8 1 0 0 1 1 1 1 NUC130/3NT domain MRP-L51 PF10244.9 EGG02198.1 - 0.21 11.8 4.2 7.5 6.8 0.1 2.9 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit DUF2477 PF10631.9 EGG02199.1 - 2.3 8.9 6.1 8.3 7.1 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) SnoaL_2 PF12680.7 EGG02201.1 - 7.4e-06 26.5 0.1 1e-05 26.1 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF1002 PF06207.11 EGG02201.1 - 0.0067 16.0 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1002) DUF4440 PF14534.6 EGG02201.1 - 0.025 15.0 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Cation_efflux PF01545.21 EGG02203.1 - 3.8e-10 39.8 1.6 4.7e-10 39.5 1.2 1.5 1 1 0 1 1 1 1 Cation efflux family FYDLN_acid PF09538.10 EGG02204.1 - 0.95 10.2 12.0 0.8 10.4 6.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Presenilin PF01080.17 EGG02204.1 - 2.1 7.0 4.9 2.6 6.7 4.9 1.1 1 0 0 1 1 1 0 Presenilin Afi1 PF07792.12 EGG02204.1 - 3.1 8.3 9.1 0.8 10.2 4.4 1.9 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PIG-U PF06728.13 EGG02205.1 - 2.1e-79 267.3 37.9 2.7e-79 267.0 37.9 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U bVLRF1 PF18826.1 EGG02208.1 - 3.6e-52 176.2 0.4 1.2e-51 174.5 0.4 1.9 1 1 0 1 1 1 1 bacteroidetes VLRF1 release factor zf-C2H2_jaz PF12171.8 EGG02208.1 - 0.0087 16.3 0.1 0.02 15.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Ank PF00023.30 EGG02208.1 - 0.0098 16.3 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EGG02208.1 - 0.056 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG02208.1 - 0.079 13.6 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.6 EGG02208.1 - 0.13 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) CENP-B_dimeris PF09026.10 EGG02208.1 - 0.25 11.7 3.6 0.61 10.5 3.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain KAP PF05804.12 EGG02209.1 - 0.047 11.8 0.1 0.071 11.2 0.1 1.2 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Alpha-2-MRAP_C PF06401.11 EGG02209.1 - 0.14 12.1 3.9 0.072 13.0 0.9 1.8 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Resistin PF06954.11 EGG02211.1 - 0.031 14.8 2.6 6 7.5 0.1 3.1 2 1 0 2 2 2 0 Resistin HA2 PF04408.23 EGG02213.1 - 0.014 15.6 1.5 0.038 14.3 1.5 1.6 1 0 0 1 1 1 0 Helicase associated domain (HA2) DDHD PF02862.17 EGG02213.1 - 0.037 14.2 6.5 0.054 13.7 6.5 1.2 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 EGG02213.1 - 0.92 8.2 7.7 1.1 7.9 7.7 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 EGG02213.1 - 2.5 6.9 9.3 3 6.6 9.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Orf78 PF06024.12 EGG02213.1 - 3.2 8.1 7.1 1.1 9.5 4.4 1.6 2 0 0 2 2 2 0 Orf78 (ac78) RNA_pol_Rbc25 PF08292.12 EGG02215.1 - 4.6e-28 98.0 0.0 6e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EGG02215.1 - 3.8e-15 56.0 0.0 6.2e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF4822 PF16103.5 EGG02218.1 - 0.057 13.7 0.5 0.087 13.1 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4822) DUF1667 PF07892.11 EGG02219.1 - 0.18 11.9 0.1 0.27 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) Cu-oxidase_3 PF07732.15 EGG02224.1 - 1.6e-43 147.5 7.6 5.3e-43 145.8 0.0 4.1 5 0 0 5 5 5 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG02224.1 - 2.7e-28 98.4 0.4 1.4e-23 83.2 0.0 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGG02224.1 - 7.3e-14 52.2 0.0 7.4e-13 48.9 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase MFS_1 PF07690.16 EGG02225.1 - 5.1e-19 68.4 29.9 2.6e-18 66.1 29.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG02225.1 - 8.5e-10 38.1 22.7 7.8e-09 34.9 4.3 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter Imm17 PF15562.6 EGG02225.1 - 0.099 12.5 3.4 2.6 8.0 0.7 3.4 2 1 0 2 2 2 0 Immunity protein 17 DUF2109 PF09882.9 EGG02225.1 - 0.21 11.6 2.4 0.48 10.5 0.2 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Resistin PF06954.11 EGG02226.1 - 0.03 14.9 2.3 0.069 13.7 2.3 1.7 1 0 0 1 1 1 0 Resistin SR-25 PF10500.9 EGG02226.1 - 2 8.0 26.7 0.34 10.5 20.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Memo PF01875.17 EGG02227.1 - 1.2e-41 142.7 0.0 1.4e-41 142.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein MtN3_slv PF03083.16 EGG02227.1 - 0.049 13.7 0.5 0.2 11.7 0.0 2.2 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange Toxin_11 PF07473.11 EGG02228.1 - 8.1 6.6 8.1 57 3.9 0.0 4.0 4 0 0 4 4 4 0 Spasmodic peptide gm9a; conotoxin from Conus species gag-asp_proteas PF13975.6 EGG02230.1 - 0.003 18.1 0.0 0.012 16.2 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGG02230.1 - 0.022 15.4 0.0 0.052 14.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease LIF_OSM PF01291.17 EGG02230.1 - 0.12 12.5 2.0 0.14 12.3 0.3 2.0 2 0 0 2 2 2 0 LIF / OSM family IL2 PF00715.17 EGG02230.1 - 0.31 11.0 5.2 0.098 12.6 1.2 2.1 1 1 1 2 2 2 0 Interleukin 2 DUF2120 PF09893.9 EGG02230.1 - 1.9 8.6 7.0 1.9 8.6 2.4 2.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF1216 PF06746.11 EGG02230.1 - 1.9 8.5 8.0 0.96 9.5 2.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) NPV_P10 PF05531.12 EGG02230.1 - 4.7 7.7 9.9 18 5.9 7.4 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3736 PF12540.8 EGG02233.1 - 0.062 13.4 0.1 0.076 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) SNF2_N PF00176.23 EGG02236.1 - 3.9e-30 104.8 0.1 5.1e-30 104.4 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGG02236.1 - 2.6e-06 27.3 0.0 3.5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGG02236.1 - 0.00044 20.3 0.0 0.00056 19.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGG02237.1 - 1.9e-12 47.5 0.0 3.2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PPDK_N PF01326.19 EGG02237.1 - 0.1 11.8 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DUF3195 PF11424.8 EGG02239.1 - 0.1 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGG02239.1 - 0.15 11.0 0.4 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 NUC194 domain DUF2170 PF09938.9 EGG02239.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) TFIIA PF03153.13 EGG02245.1 - 0.00035 20.7 8.1 0.00041 20.5 8.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 EGG02245.1 - 0.097 12.5 3.9 0.16 11.8 3.9 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Menin PF05053.13 EGG02245.1 - 0.28 9.5 9.8 0.41 9.0 9.8 1.2 1 0 0 1 1 1 0 Menin Cwf_Cwc_15 PF04889.12 EGG02245.1 - 2.6 7.7 14.2 3.9 7.1 14.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 EGG02245.1 - 4.8 6.7 17.0 6.9 6.2 17.0 1.2 1 0 0 1 1 1 0 PPP4R2 Opiods_neuropep PF01160.18 EGG02248.1 - 0.11 12.6 0.2 0.67 10.1 0.0 2.1 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide TFIIA PF03153.13 EGG02249.1 - 0.0092 16.0 11.3 0.0082 16.2 11.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 EGG02249.1 - 0.11 11.9 17.9 0.13 11.6 17.9 1.1 1 0 0 1 1 1 0 SDA1 Trypan_PARP PF05887.11 EGG02249.1 - 6.2 6.8 10.5 8.8 6.3 10.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PGBA_C PF15437.6 EGG02250.1 - 0.35 11.3 10.3 0.57 10.6 10.3 1.3 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal zf-CCHC_2 PF13696.6 EGG02252.1 - 0.00016 21.4 1.2 0.00037 20.3 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGG02252.1 - 0.0081 16.2 0.9 0.032 14.3 0.7 2.0 2 0 0 2 2 2 1 Zinc knuckle UPF0181 PF03701.14 EGG02254.1 - 0.0015 18.1 0.2 0.0037 16.9 0.2 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0181) DUF3734 PF12536.8 EGG02254.1 - 0.031 14.6 0.6 0.069 13.5 0.5 1.8 1 1 0 1 1 1 0 Patatin phospholipase Saw1 PF11561.8 EGG02254.1 - 0.038 13.5 2.3 0.064 12.8 2.3 1.4 1 0 0 1 1 1 0 Single strand annealing-weakened 1 peroxidase PF00141.23 EGG02255.1 - 1.3e-28 100.2 0.0 2.6e-27 96.0 0.0 2.1 2 0 0 2 2 2 2 Peroxidase Cu-oxidase_3 PF07732.15 EGG02257.1 - 5.8e-35 119.9 9.3 1.1e-33 115.7 2.3 4.2 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG02257.1 - 4.8e-27 94.4 3.1 6e-24 84.3 0.0 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGG02257.1 - 7.1e-26 91.2 0.1 4.8e-24 85.3 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase SET PF00856.28 EGG02258.1 - 1.5e-14 54.8 1.5 5.2e-14 53.0 0.1 2.6 2 1 0 2 2 2 1 SET domain AWS PF17907.1 EGG02258.1 - 4e-09 36.4 2.8 1.2e-08 34.9 2.8 1.8 1 0 0 1 1 1 1 AWS domain Cas_Csy4 PF09618.10 EGG02258.1 - 0.41 10.8 4.1 0.1 12.7 0.5 1.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) ATG22 PF11700.8 EGG02259.1 - 3.2e-91 306.4 21.3 3.6e-91 306.2 21.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EGG02259.1 - 2.2e-08 33.5 33.4 1.4e-06 27.5 19.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF2721 PF11026.8 EGG02259.1 - 0.017 15.0 1.2 0.017 15.0 1.2 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF2721) Use1 PF09753.9 EGG02260.1 - 8.9e-15 55.1 2.4 2.5e-14 53.6 0.0 2.4 3 0 0 3 3 3 1 Membrane fusion protein Use1 HisKA_3 PF07730.13 EGG02260.1 - 0.0021 18.5 2.9 0.94 10.0 0.2 2.6 2 1 0 2 2 2 2 Histidine kinase FlgN PF05130.12 EGG02260.1 - 0.87 10.1 6.8 13 6.2 2.5 2.5 2 0 0 2 2 2 0 FlgN protein YhzD PF14120.6 EGG02261.1 - 0.095 12.8 1.6 2.1 8.5 0.1 3.0 2 1 1 3 3 3 0 YhzD-like protein DUF1127 PF06568.11 EGG02262.1 - 2.8e-05 23.7 0.1 0.00026 20.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1127) Pkinase PF00069.25 EGG02263.1 - 1.3e-74 251.0 0.0 1.4e-74 250.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG02263.1 - 6.2e-43 146.9 0.0 7.5e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG02263.1 - 9.5e-09 35.0 0.0 1.6e-08 34.2 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGG02263.1 - 0.00035 20.0 0.0 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG02263.1 - 0.029 14.3 0.4 0.44 10.4 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG02263.1 - 0.037 13.0 0.1 0.047 12.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FSA_C PF10479.9 EGG02265.1 - 2.6 6.0 11.2 2.9 5.9 11.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Cyt-b5 PF00173.28 EGG02266.1 - 0.011 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain ATG22 PF11700.8 EGG02267.1 - 5.5e-112 374.8 19.2 6.2e-112 374.7 19.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EGG02267.1 - 2.3e-10 39.9 32.4 5.4e-08 32.1 4.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily BT1 PF03092.16 EGG02267.1 - 0.00081 17.7 2.8 0.0013 17.0 2.8 1.3 1 0 0 1 1 1 1 BT1 family LptF_LptG PF03739.14 EGG02268.1 - 0.031 13.1 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Orf78 PF06024.12 EGG02268.1 - 0.046 14.0 0.2 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Orf78 (ac78) PBP1_TM PF14812.6 EGG02268.1 - 0.25 11.8 3.2 9.9 6.6 1.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Catalase PF00199.19 EGG02269.1 - 1.7e-161 537.6 0.0 2.2e-161 537.3 0.0 1.0 1 0 0 1 1 1 1 Catalase Sulfate_transp PF00916.20 EGG02270.1 - 1.3e-58 198.6 23.3 1.3e-58 198.6 23.3 1.5 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 EGG02270.1 - 3.3e-11 42.9 0.1 6.4e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 EGG02270.1 - 9.4e-06 25.6 0.0 2.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS_2 PF13466.6 EGG02270.1 - 0.0012 19.2 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain UCR_UQCRX_QCR9 PF05365.12 EGG02270.1 - 0.059 13.3 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Tyrosinase PF00264.20 EGG02274.1 - 1.9e-31 110.1 7.8 1.9e-31 110.1 7.8 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase IF3_C PF00707.22 EGG02275.1 - 9e-07 28.8 0.2 2.5e-06 27.3 0.2 1.8 1 1 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 EGG02275.1 - 0.00026 21.2 0.1 0.00084 19.6 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 EGG02275.1 - 0.007 16.1 0.2 0.014 15.1 0.1 1.6 1 1 0 1 1 1 1 Mitochondrial translation initiation factor HORMA PF02301.18 EGG02276.1 - 3.4e-22 79.1 2.9 4.2e-22 78.8 2.9 1.1 1 0 0 1 1 1 1 HORMA domain Arcadin_1 PF18653.1 EGG02276.1 - 0.0052 16.8 0.1 0.01 15.9 0.1 1.5 1 0 0 1 1 1 1 Arcadin 1 bacHORMA_2 PF18173.1 EGG02276.1 - 0.0068 16.3 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial HORMA domain 2 DUF5101 PF17031.5 EGG02276.1 - 0.0097 16.0 2.7 0.079 13.1 0.4 3.0 2 1 0 3 3 3 1 Domain of unknown function (DUF5101) DnaJ-X PF14308.6 EGG02276.1 - 0.054 12.9 1.0 0.083 12.3 1.0 1.4 1 0 0 1 1 1 0 X-domain of DnaJ-containing MIP PF00230.20 EGG02278.1 - 2.4e-35 122.3 15.4 2.7e-35 122.1 15.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein HXXEE PF13787.6 EGG02278.1 - 2.6 8.9 9.8 9.3 7.1 9.8 2.0 1 1 0 1 1 1 0 Protein of unknown function with HXXEE motif Put_Phosphatase PF06888.12 EGG02282.1 - 1.5e-50 171.8 1.2 1.7e-50 171.6 1.2 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 EGG02282.1 - 2.1e-07 31.5 0.0 7.7e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EGG02282.1 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) 5_nucleotid PF05761.14 EGG02282.1 - 0.0033 16.4 0.1 0.0068 15.4 0.1 1.5 1 1 0 1 1 1 1 5' nucleotidase family Hydrolase_3 PF08282.12 EGG02282.1 - 0.0084 15.9 0.2 0.013 15.2 0.2 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 EGG02282.1 - 0.017 14.6 0.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) HNF-1_N PF04814.13 EGG02282.1 - 0.15 12.7 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus HAD_2 PF13419.6 EGG02282.1 - 3.4 7.7 5.7 89 3.1 0.0 3.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TIP49 PF06068.13 EGG02283.1 - 0.12 11.5 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DUF3391 PF11871.8 EGG02285.1 - 4.6 7.8 8.0 13 6.3 7.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) F-box PF00646.33 EGG02289.1 - 2.1e-07 30.6 2.3 4.7e-07 29.5 2.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGG02289.1 - 0.00027 20.7 0.1 0.00067 19.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like SPRY PF00622.28 EGG02290.1 - 1.6e-18 66.9 0.0 2.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 SPRY domain TMEM154 PF15102.6 EGG02290.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF5527 PF17665.1 EGG02290.1 - 0.17 11.4 0.9 0.35 10.4 0.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5527) UPF0242 PF06785.11 EGG02292.1 - 9.7 6.3 7.7 0.22 11.6 0.8 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3439 PF11921.8 EGG02294.1 - 4.3 7.3 10.3 3.5 7.6 7.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Pkinase PF00069.25 EGG02295.1 - 0.027 13.8 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain FAP PF07174.11 EGG02295.1 - 0.062 12.8 9.1 0.066 12.7 9.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PRCC PF10253.9 EGG02295.1 - 1.6 9.5 5.3 2 9.2 5.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting STAT1_TAZ2bind PF12162.8 EGG02296.1 - 0.079 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain TGase_elicitor PF16683.5 EGG02296.1 - 0.11 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase elicitor Syja_N PF02383.18 EGG02297.1 - 1.4e-11 44.3 0.0 1.8e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EGG02298.1 - 5.7e-11 42.4 0.0 7.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1335 PF07056.11 EGG02298.1 - 0.02 15.0 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1335) RNA_pol_Rpb1_5 PF04998.17 EGG02301.1 - 1.9e-23 83.3 0.0 2.3e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Colicin_D PF11429.8 EGG02301.1 - 0.021 15.3 0.3 0.04 14.4 0.3 1.5 1 0 0 1 1 1 0 Colicin D Herpes_heli_pri PF05774.11 EGG02302.1 - 0.022 15.0 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component FYDLN_acid PF09538.10 EGG02302.1 - 0.21 12.3 15.2 3.7e+02 1.9 15.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CxC1 PF18802.1 EGG02305.1 - 1.6e-23 82.9 1.1 3e-23 82.0 1.1 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG02305.1 - 0.00046 20.3 0.3 0.00093 19.3 0.1 1.6 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases Herpes_UL32 PF06070.11 EGG02305.1 - 0.056 11.2 0.5 0.078 10.7 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 CytochromB561_N PF09786.9 EGG02309.1 - 3.1 6.7 8.6 5.7 5.8 8.6 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal Mago-bind PF09282.10 EGG02311.1 - 4.1e-14 52.1 2.8 4.1e-14 52.1 2.8 1.7 2 0 0 2 2 2 1 Mago binding SspK PF08176.12 EGG02311.1 - 0.013 15.8 3.2 0.87 9.9 0.0 3.1 3 0 0 3 3 3 0 Small acid-soluble spore protein K family Brix PF04427.18 EGG02312.1 - 4e-24 85.8 0.0 6.4e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Brix domain Hid1 PF12722.7 EGG02312.1 - 1.2 7.2 4.6 2.2 6.3 4.6 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dicty_REP PF05086.12 EGG02312.1 - 6 4.7 4.7 8.5 4.2 4.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SHMT PF00464.19 EGG02313.1 - 7.8e-21 74.1 0.0 9.6e-21 73.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF2773 PF10971.8 EGG02313.1 - 0.045 13.9 0.0 0.072 13.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2773) VPDSG-CTERM PF18205.1 EGG02313.1 - 0.32 10.9 0.2 0.32 10.9 0.2 1.7 2 0 0 2 2 2 0 VPDSG-CTERM motif DUF1883 PF08980.10 EGG02315.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) zf-CCHC PF00098.23 EGG02316.1 - 8.3e-18 63.6 22.4 1e-06 28.5 2.2 4.2 4 0 0 4 4 4 4 Zinc knuckle HscB_4_cys PF18256.1 EGG02316.1 - 0.038 13.8 1.7 3.9 7.4 0.1 2.8 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif zf-CCHC_4 PF14392.6 EGG02316.1 - 0.04 13.6 10.6 0.84 9.4 0.7 4.0 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGG02316.1 - 0.21 11.6 5.5 18 5.4 0.1 3.4 2 1 1 3 3 3 0 Zinc knuckle Biotin_lipoyl PF00364.22 EGG02317.1 - 6.7e-15 54.7 0.0 1.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EGG02317.1 - 2.3e-10 40.6 0.0 5.1e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EGG02317.1 - 0.067 13.0 0.2 2.4 8.1 0.0 3.0 3 0 0 3 3 3 0 Biotin-lipoyl like zf-C3HC4_3 PF13920.6 EGG02319.1 - 0.00014 21.6 7.3 0.00026 20.8 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG02319.1 - 0.00041 20.1 8.3 0.00093 19.0 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG02319.1 - 0.0029 17.9 10.0 0.0029 17.9 10.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.6 EGG02319.1 - 0.0073 16.1 3.7 0.0073 16.1 3.7 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EGG02319.1 - 0.033 14.1 8.4 0.089 12.8 8.5 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG02319.1 - 0.063 13.3 8.9 0.13 12.3 8.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EGG02319.1 - 0.73 9.7 9.8 7.3 6.5 9.9 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zn-C2H2_12 PF18112.1 EGG02319.1 - 6.3 7.4 10.2 4.3 7.9 4.2 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain MMS1_N PF10433.9 EGG02320.1 - 1e-153 512.5 0.1 3.9e-153 510.6 0.0 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGG02320.1 - 1.1e-95 320.6 0.0 6.7e-95 318.1 0.0 2.3 3 0 0 3 3 3 1 CPSF A subunit region RPA_C PF08784.11 EGG02321.1 - 8.4e-10 39.2 0.6 1.7e-09 38.3 0.1 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EGG02321.1 - 1.2e-05 25.1 0.2 3e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 EGG02321.1 - 0.0045 16.8 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 Tubulin PF00091.25 EGG02323.1 - 1.9e-68 230.5 0.0 1.1e-66 224.8 0.0 2.2 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGG02323.1 - 2e-44 150.8 0.4 3.3e-44 150.1 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGG02323.1 - 0.00013 21.8 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EGG02323.1 - 0.0082 16.4 0.0 2.7 8.3 0.0 2.4 2 0 0 2 2 2 2 Misato Segment II tubulin-like domain DEAD_2 PF06733.15 EGG02323.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 DEAD_2 p450 PF00067.22 EGG02324.1 - 1.7e-08 33.6 0.0 2.1e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Choline_transpo PF04515.12 EGG02325.1 - 1.3e-69 235.0 15.7 1.3e-69 235.0 15.7 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter API5 PF05918.11 EGG02326.1 - 0.02 13.7 4.2 0.023 13.5 4.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GSHPx PF00255.19 EGG02328.1 - 4.3e-39 132.4 0.3 5.5e-39 132.1 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 EGG02328.1 - 2e-05 24.3 0.1 4.3e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGG02328.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family DUF1573 PF07610.11 EGG02328.1 - 0.0013 18.7 0.0 0.09 12.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1573) DNA_binding_1 PF01035.20 EGG02331.1 - 3.5e-26 91.1 0.0 6e-26 90.4 0.0 1.4 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Collagen_bind_2 PF12904.7 EGG02332.1 - 0.16 11.9 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase Zn_clus PF00172.18 EGG02333.1 - 2.4e-05 24.3 9.3 4.9e-05 23.4 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G-alpha PF00503.20 EGG02336.1 - 6.3e-06 25.6 1.1 6.3e-06 25.6 1.1 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Dynactin_p22 PF07426.11 EGG02337.1 - 0.00044 20.1 1.0 0.00079 19.3 1.0 1.4 1 1 0 1 1 1 1 Dynactin subunit p22 DUF848 PF05852.11 EGG02337.1 - 0.084 13.0 1.2 0.11 12.6 0.2 1.7 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CSD PF00313.22 EGG02338.1 - 5.1e-08 32.6 0.0 8.7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain LSM PF01423.22 EGG02339.1 - 1.5e-20 72.6 0.3 1.7e-20 72.5 0.3 1.0 1 0 0 1 1 1 1 LSM domain Glyco_hydro_88 PF07470.13 EGG02340.1 - 7.5e-16 58.1 0.2 1.3e-15 57.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 CxC1 PF18802.1 EGG02341.1 - 3.9e-17 62.3 0.2 5.6e-16 58.6 0.2 2.2 1 1 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG02341.1 - 0.007 16.5 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG02341.1 - 0.013 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGG02341.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase CxC5 PF18718.1 EGG02342.1 - 9.9e-32 109.5 4.0 1.5e-31 108.9 4.0 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 EGG02342.1 - 0.18 11.7 0.9 0.3 10.9 0.1 1.8 2 0 0 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases CPSase_L_D2 PF02786.17 EGG02344.1 - 1.1 8.7 2.4 2.2 7.7 2.4 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF3915 PF13054.6 EGG02344.1 - 1.3 9.0 7.4 2.9 7.9 7.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) RNA_pol_Rpb5_C PF01191.19 EGG02346.1 - 6.8e-29 99.5 0.1 7.4e-29 99.4 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain TMA7 PF09072.10 EGG02347.1 - 1.6e-20 73.6 13.9 2.1e-20 73.3 13.9 1.1 1 0 0 1 1 1 1 Translation machinery associated TMA7 Cu-oxidase_3 PF07732.15 EGG02349.1 - 1.4e-42 144.4 7.5 4.1e-41 139.7 2.0 4.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG02349.1 - 8.6e-30 103.3 1.5 3.2e-21 75.5 0.0 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGG02349.1 - 1.7e-21 77.0 0.4 1.1e-19 71.1 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase CactinC_cactus PF09732.9 EGG02350.1 - 0.051 13.5 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein AMP-binding PF00501.28 EGG02351.1 - 8e-57 192.7 0.0 1.2e-56 192.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGG02351.1 - 2e-22 79.5 1.0 3.6e-22 78.7 1.0 1.4 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EGG02351.1 - 6.3e-13 48.9 0.0 6.1e-05 23.3 0.0 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site Peptidase_C74 PF12387.8 EGG02351.1 - 0.0034 16.9 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 Pestivirus NS2 peptidase CBP_BcsQ PF06564.12 EGG02351.1 - 0.073 12.5 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AMP-binding_C PF13193.6 EGG02351.1 - 0.16 13.0 0.0 0.36 11.8 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Synaptobrevin PF00957.21 EGG02355.1 - 1.5e-28 98.4 3.3 1.5e-28 98.4 3.3 1.9 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 EGG02355.1 - 3.3e-24 84.7 0.1 7.1e-24 83.7 0.1 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain PLDc_2 PF13091.6 EGG02355.1 - 0.037 13.9 0.1 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 PLD-like domain MFS_1 PF07690.16 EGG02356.1 - 1.1e-18 67.3 47.6 2.9e-15 56.1 29.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PLA2_B PF01735.18 EGG02357.1 - 4.8e-84 282.5 0.1 7.2e-84 281.9 0.1 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 EGG02357.1 - 0.001 19.3 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase NAD_binding_7 PF13241.6 EGG02359.1 - 1.6e-28 99.1 0.0 3.2e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EGG02359.1 - 2.4e-20 71.9 1.7 4.8e-20 71.0 1.7 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EGG02359.1 - 1.2e-13 50.2 0.4 2.5e-13 49.2 0.4 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 EGG02359.1 - 0.031 14.3 0.1 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PAF-AH_p_II PF03403.13 EGG02360.1 - 1.9e-23 82.6 0.0 2.5e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 EGG02360.1 - 0.0012 18.2 0.1 0.0022 17.3 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EGG02360.1 - 0.0061 15.5 0.0 0.0082 15.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EGG02360.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase RNA12 PF10443.9 EGG02361.1 - 3.9e-95 319.2 0.2 1.9e-61 208.2 0.0 2.3 1 1 0 2 2 2 2 RNA12 protein ATPase_2 PF01637.18 EGG02361.1 - 2.6e-06 27.5 0.2 1.1e-05 25.4 0.0 2.2 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 EGG02361.1 - 3.1e-05 23.7 0.0 7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 EGG02361.1 - 0.0013 19.2 0.0 0.0038 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain Atg14 PF10186.9 EGG02361.1 - 0.0075 15.4 1.5 0.016 14.3 1.5 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_14 PF13173.6 EGG02361.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Turandot PF07240.11 EGG02361.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot DUF4534 PF15049.6 EGG02362.1 - 0.18 11.5 2.0 0.3 10.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) Hist_deacetyl PF00850.19 EGG02363.1 - 3.6e-77 259.8 0.0 4.4e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain HEAT PF02985.22 EGG02364.1 - 5.9e-08 32.3 4.9 1.8 9.0 0.0 7.3 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 EGG02364.1 - 0.0001 22.6 0.7 0.0041 17.5 0.0 3.9 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 EGG02364.1 - 0.0028 18.1 4.4 14 6.3 0.0 5.5 5 0 0 5 5 5 2 HEAT-like repeat CLASP_N PF12348.8 EGG02364.1 - 0.0037 16.9 0.0 0.16 11.5 0.0 3.2 3 1 1 4 4 4 1 CLASP N terminal Cnd1 PF12717.7 EGG02364.1 - 0.011 15.8 1.2 1.2 9.2 0.0 3.9 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Elicitin PF00964.17 EGG02365.1 - 0.054 13.6 2.3 0.08 13.0 0.6 2.1 1 1 1 2 2 2 0 Elicitin zf-C2H2 PF00096.26 EGG02366.1 - 1.1e-08 35.1 8.9 1.4e-05 25.3 1.6 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG02366.1 - 2.3e-08 34.2 8.9 0.00095 19.8 1.9 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 EGG02366.1 - 8.6e-05 22.8 4.4 0.00018 21.7 4.4 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 EGG02366.1 - 0.0033 17.8 5.6 2.7 8.6 0.0 3.6 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_9 PF16293.5 EGG02366.1 - 0.01 15.6 0.6 2.7 7.9 0.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 EGG02366.1 - 0.018 14.8 2.7 1.4 8.8 0.3 2.2 1 1 1 2 2 2 0 GAGA factor FOXP-CC PF16159.5 EGG02366.1 - 0.037 14.7 1.7 2.9 8.6 0.2 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 EGG02366.1 - 0.042 13.6 6.9 0.14 12.0 0.2 2.7 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 EGG02366.1 - 0.062 13.3 3.4 0.52 10.4 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EGG02366.1 - 0.075 13.2 1.3 4.2 7.5 0.1 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_2 PF12756.7 EGG02366.1 - 0.18 12.1 1.0 7.8 6.9 0.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 EGG02366.1 - 0.37 10.7 2.2 16 5.5 0.3 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-met2 PF12907.7 EGG02366.1 - 0.38 10.9 5.7 0.1 12.7 2.5 1.7 2 0 0 2 2 2 0 Zinc-binding zf-C2H2_jaz PF12171.8 EGG02366.1 - 0.66 10.3 4.5 14 6.1 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Snf7 PF03357.21 EGG02367.1 - 3.8e-24 85.2 12.2 4.3e-24 85.0 12.2 1.1 1 0 0 1 1 1 1 Snf7 Cutinase PF01083.22 EGG02369.1 - 5.6e-27 94.8 0.2 7.1e-27 94.5 0.2 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 EGG02369.1 - 0.0088 15.9 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 EGG02369.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain UPF0565 PF10561.9 EGG02369.1 - 0.19 10.9 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 PGAP1 PF07819.13 EGG02369.1 - 0.21 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF726 PF05277.12 EGG02369.1 - 0.58 9.0 0.0 0.58 9.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF726) Cutinase PF01083.22 EGG02370.1 - 2.6e-23 82.9 0.1 3.7e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 EGG02370.1 - 0.0048 16.8 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 EGG02370.1 - 0.0086 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain PGAP1 PF07819.13 EGG02370.1 - 0.061 13.0 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 EGG02370.1 - 0.087 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EGG02370.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain UPF0565 PF10561.9 EGG02370.1 - 0.25 10.5 0.0 0.33 10.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 ICMT PF04140.14 EGG02371.1 - 3.4e-23 81.9 0.6 3.4e-23 81.9 0.6 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGG02371.1 - 1.2e-12 48.1 1.6 1.2e-12 48.1 1.6 2.6 2 1 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 EGG02371.1 - 0.0001 21.9 3.9 0.0001 21.9 3.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 EGG02371.1 - 0.0036 16.9 0.8 0.0087 15.6 0.0 1.8 1 1 1 2 2 2 1 NnrU protein Steroid_dh PF02544.16 EGG02371.1 - 1.2 9.2 19.3 0.016 15.2 9.9 2.2 1 1 1 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase DFP PF04127.15 EGG02372.1 - 9.5e-18 64.7 0.0 3.8e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein SIS_2 PF13580.6 EGG02372.1 - 0.057 13.4 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 SIS domain TruD PF01142.18 EGG02373.1 - 2e-71 241.0 0.0 5.3e-69 233.0 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Cu-oxidase_2 PF07731.14 EGG02374.1 - 3.4e-37 127.2 2.1 8.6e-31 106.5 0.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGG02374.1 - 2e-35 121.3 9.6 2.7e-34 117.7 1.9 4.1 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 EGG02374.1 - 6.3e-20 71.9 0.1 1.2e-17 64.4 0.0 3.2 3 0 0 3 3 3 1 Multicopper oxidase Pox_L3_FP4 PF03339.14 EGG02374.1 - 0.038 13.0 0.3 0.053 12.5 0.3 1.2 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein IDO PF01231.18 EGG02377.1 - 2.1e-125 418.9 0.0 2.4e-125 418.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase SET PF00856.28 EGG02378.1 - 4.4e-11 43.5 0.5 4.8e-10 40.1 0.1 2.7 2 1 0 2 2 2 1 SET domain SAF PF08666.12 EGG02378.1 - 0.052 14.2 0.1 1.5 9.5 0.0 2.5 2 0 0 2 2 2 0 SAF domain Alpha_kinase PF02816.18 EGG02380.1 - 1.6e-08 34.9 0.3 2e-08 34.6 0.3 1.1 1 0 0 1 1 1 1 Alpha-kinase family SET PF00856.28 EGG02382.1 - 1.1e-07 32.4 0.2 6.2e-07 30.0 0.1 2.2 2 1 0 2 2 2 1 SET domain SET PF00856.28 EGG02383.1 - 1e-10 42.3 0.2 4.8e-10 40.1 0.2 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.12 EGG02383.1 - 0.19 12.4 0.1 3.9 8.2 0.0 2.3 2 0 0 2 2 2 0 SAF domain Sugar_tr PF00083.24 EGG02384.1 - 6.4e-76 256.0 16.6 1.6e-75 254.7 16.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG02384.1 - 1e-25 90.4 26.7 1e-25 90.4 26.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EGG02384.1 - 1e-05 25.0 5.4 1e-05 25.0 5.4 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EGG02384.1 - 4.1e-05 22.1 0.0 0.00015 20.2 0.0 2.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_3_2 PF04550.12 EGG02384.1 - 0.17 12.4 7.2 0.58 10.7 7.2 1.9 1 0 0 1 1 1 0 Phage holin family 2 DUF4142 PF13628.6 EGG02386.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) IDO PF01231.18 EGG02388.1 - 1.6e-117 393.0 0.0 1.9e-117 392.7 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Pkinase PF00069.25 EGG02389.1 - 3.1e-74 249.7 0.0 3.8e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG02389.1 - 3.1e-32 111.9 0.0 4.1e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG02389.1 - 3.2e-08 33.2 0.0 4.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGG02389.1 - 1.4e-05 24.1 0.0 2.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGG02389.1 - 0.00018 21.5 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGG02389.1 - 0.0021 17.4 0.1 0.0034 16.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family JmjN PF02375.17 EGG02390.1 - 9.3e-14 51.1 0.2 1.4e-13 50.5 0.2 1.3 1 0 0 1 1 1 1 jmjN domain JmjC PF02373.22 EGG02391.1 - 3e-38 130.7 0.2 4e-38 130.3 0.2 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase DEAD PF00270.29 EGG02392.1 - 3.4e-47 160.5 0.0 5.6e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG02392.1 - 2.5e-31 108.3 0.1 1.3e-30 106.0 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG02392.1 - 8.4e-07 29.2 0.2 2.8e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGG02392.1 - 0.00013 21.3 2.6 0.00025 20.3 0.0 2.3 2 1 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase E7 PF00527.18 EGG02392.1 - 0.068 13.4 2.8 0.16 12.2 2.8 1.6 1 0 0 1 1 1 0 E7 protein, Early protein CENP-B_dimeris PF09026.10 EGG02392.1 - 2.1 8.8 7.4 4.1 7.8 7.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF382 PF04037.13 EGG02393.1 - 1.9e-58 196.1 1.7 3.5e-58 195.3 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 EGG02393.1 - 1.4e-19 69.6 5.2 3.1e-19 68.6 5.2 1.6 1 0 0 1 1 1 1 PSP DUF1192 PF06698.11 EGG02393.1 - 0.49 10.5 3.5 23 5.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) PLA2_B PF01735.18 EGG02394.1 - 1.7e-78 264.3 0.1 3.8e-78 263.1 0.1 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 EGG02394.1 - 0.00019 21.7 0.1 0.00042 20.5 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase PLA2_B PF01735.18 EGG02396.1 - 3.8e-87 292.8 0.1 5.7e-87 292.2 0.1 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 EGG02396.1 - 7.9e-06 26.2 0.1 2.2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase HDC PF02329.16 EGG02398.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Histidine carboxylase PI chain CDC27 PF09507.10 EGG02399.1 - 8.9 5.6 33.1 0.28 10.5 19.5 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Cutinase PF01083.22 EGG02403.1 - 4.5e-27 95.1 0.4 5.7e-27 94.8 0.4 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EGG02403.1 - 0.01 15.4 0.1 0.014 14.9 0.1 1.1 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.11 EGG02403.1 - 0.034 14.0 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF1749 PF08538.10 EGG02403.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Cutinase PF01083.22 EGG02404.1 - 1.3e-24 87.2 0.1 1.5e-24 86.9 0.1 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 EGG02404.1 - 0.0023 17.8 0.0 0.0034 17.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF726 PF05277.12 EGG02404.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PE-PPE PF08237.11 EGG02404.1 - 0.059 12.9 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 PE-PPE domain UPF0565 PF10561.9 EGG02404.1 - 0.12 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Abhydrolase_1 PF00561.20 EGG02404.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold EMP24_GP25L PF01105.24 EGG02405.1 - 1.6e-49 168.4 0.2 1.8e-49 168.2 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MFS_1 PF07690.16 EGG02406.1 - 3.2e-35 121.7 29.9 3.2e-35 121.7 29.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily AgrB PF04647.15 EGG02406.1 - 0.15 11.4 0.0 0.15 11.4 0.0 3.1 2 1 1 3 3 3 0 Accessory gene regulator B DUF373 PF04123.13 EGG02406.1 - 1.6 8.1 9.2 2.9 7.3 8.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF373) tRNA-synt_2d PF01409.20 EGG02407.1 - 8.7e-87 290.6 0.0 1.3e-86 290.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EGG02407.1 - 1.8e-15 57.0 0.6 1.8e-15 57.0 0.6 2.4 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EGG02407.1 - 2.3e-06 27.2 0.0 0.00037 20.0 0.0 2.8 3 0 0 3 3 3 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 EGG02407.1 - 7.3e-05 22.8 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 EGG02407.1 - 0.00058 19.0 0.2 0.013 14.6 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) IF3_N PF05198.16 EGG02407.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Proton_antipo_M PF00361.20 EGG02408.1 - 7e-15 55.0 3.8 7.6e-15 54.9 3.8 1.0 1 0 0 1 1 1 1 Proton-conducting membrane transporter Dynactin PF12455.8 EGG02409.1 - 7.2e-25 87.8 0.4 7.2e-25 87.8 0.4 2.0 2 0 0 2 2 2 1 Dynein associated protein DUF3818 PF12825.7 EGG02409.1 - 0.13 11.3 8.9 0.15 11.1 8.9 1.3 1 1 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) PCRF PF03462.18 EGG02409.1 - 1.6 8.6 9.4 3 7.7 9.4 1.6 1 0 0 1 1 1 0 PCRF domain DASH_Dad4 PF08650.10 EGG02409.1 - 3 7.9 6.6 3.6 7.6 0.4 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad4 Phage_GP20 PF06810.11 EGG02409.1 - 4 7.2 15.4 30 4.4 15.4 2.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 Methyltransf_23 PF13489.6 EGG02410.1 - 5.5e-07 29.6 0.0 6.1e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EGG02410.1 - 1.9e-05 24.3 0.0 2.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_11 PF08241.12 EGG02410.1 - 0.013 16.1 0.0 0.022 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGG02410.1 - 0.044 13.6 0.0 0.051 13.4 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGG02410.1 - 0.051 14.3 0.0 0.079 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGG02410.1 - 0.078 13.7 0.0 0.12 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EGG02410.1 - 0.16 11.3 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF43 PF01861.16 EGG02410.1 - 0.19 10.9 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Kelch_2 PF07646.15 EGG02411.1 - 0.14 12.1 1.1 20 5.4 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Alpha_kinase PF02816.18 EGG02412.1 - 7.3e-06 26.2 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Med13_C PF06333.12 EGG02413.1 - 0.038 13.3 0.3 0.04 13.2 0.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain IBN_N PF03810.19 EGG02414.1 - 0.00012 21.9 0.9 0.0018 18.1 0.1 3.4 3 1 1 4 4 4 1 Importin-beta N-terminal domain PXA PF02194.15 EGG02414.1 - 0.012 15.6 0.1 0.058 13.4 0.0 2.3 2 1 0 2 2 2 0 PXA domain HEAT_EZ PF13513.6 EGG02414.1 - 0.019 15.5 1.8 17 6.1 0.0 4.5 4 1 1 5 5 5 0 HEAT-like repeat HEAT PF02985.22 EGG02414.1 - 0.82 10.1 3.2 23 5.6 0.0 4.7 6 0 0 6 6 6 0 HEAT repeat DUF4746 PF15928.5 EGG02415.1 - 3.7 6.9 8.9 4.1 6.7 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Glyco_hydro_10 PF00331.20 EGG02416.1 - 5.1e-62 209.9 0.0 5.7e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PTSIIA_gutA PF03829.13 EGG02418.1 - 0.045 13.6 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 PTS system glucitol/sorbitol-specific IIA component Peroxidase_2 PF01328.17 EGG02424.1 - 1.3e-42 146.5 0.0 1.7e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 p450 PF00067.22 EGG02425.1 - 3.3e-57 194.2 0.0 4.5e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 EGG02428.1 - 3.7e-10 40.8 0.0 7.7e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG02428.1 - 1.4e-05 24.9 0.0 9.9e-05 22.1 0.0 2.3 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG02428.1 - 0.00014 21.3 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGG02428.1 - 0.00035 20.4 0.1 0.0017 18.1 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Peptidase_S9 PF00326.21 EGG02428.1 - 0.0058 16.1 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 EGG02428.1 - 0.007 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Esterase PF00756.20 EGG02428.1 - 0.04 13.5 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase UPF0227 PF05728.12 EGG02428.1 - 0.11 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Pkinase PF00069.25 EGG02429.1 - 6.6e-62 209.2 0.0 9e-41 140.0 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG02429.1 - 8.7e-30 103.8 0.0 8e-23 81.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EGG02429.1 - 1.1e-11 44.8 0.0 2.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EGG02429.1 - 0.00071 19.0 0.0 0.0047 16.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EGG02429.1 - 0.001 18.7 0.0 0.44 10.1 0.0 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGG02429.1 - 0.0045 16.9 0.1 0.018 14.9 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGG02429.1 - 0.047 13.1 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGG02429.1 - 0.047 12.8 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EGG02429.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family PAS_9 PF13426.7 EGG02429.1 - 0.13 12.6 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 PAS domain SUR7 PF06687.12 EGG02430.1 - 0.2 11.2 16.8 0.024 14.3 3.5 2.9 2 1 0 2 2 2 0 SUR7/PalI family Amastin PF07344.11 EGG02430.1 - 3.4 7.5 9.9 8.9 6.1 0.6 2.4 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF3810 PF12725.7 EGG02430.1 - 4.4 6.6 9.6 0.28 10.5 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) FKBP_C PF00254.28 EGG02431.1 - 3e-19 69.1 0.0 3.7e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PDEase_II PF02112.15 EGG02432.1 - 0.04 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II CSD2 PF17876.1 EGG02432.1 - 0.043 14.0 0.0 0.076 13.2 0.0 1.3 1 0 0 1 1 1 0 Cold shock domain Ribosomal_L29e PF01779.17 EGG02434.1 - 1.5e-21 76.4 10.8 2e-21 76.0 10.8 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Zn_clus PF00172.18 EGG02435.1 - 7.2e-05 22.8 9.6 7.2e-05 22.8 9.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGG02435.1 - 0.0017 17.4 0.8 0.002 17.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2370 PF10176.9 EGG02437.1 - 1.2e-75 254.0 0.0 1.9e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.15 EGG02437.1 - 0.026 14.9 6.5 0.32 11.5 6.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Chordopox_A13L PF05961.11 EGG02437.1 - 0.15 12.3 0.4 3.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein FACT-Spt16_Nlob PF14826.6 EGG02438.1 - 1.9e-33 115.6 0.3 4.1e-33 114.4 0.3 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EGG02438.1 - 1.6e-20 73.7 0.0 9.9e-20 71.1 0.0 2.0 1 1 1 2 2 2 1 Metallopeptidase family M24 NAM-associated PF14303.6 EGG02438.1 - 0.87 10.3 21.0 0.082 13.6 9.6 2.8 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain DrrA_P4M PF14860.6 EGG02438.1 - 4.3 7.2 12.5 3.1 7.7 5.2 2.9 3 0 0 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain FACT-Spt16_Nlob PF14826.6 EGG02439.1 - 7e-20 71.5 0.0 7.5e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EGG02440.1 - 1.9e-13 50.6 0.0 4.3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 NAM-associated PF14303.6 EGG02440.1 - 0.0022 18.7 0.1 0.0022 18.7 0.1 2.2 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain BD_b_sandwich PF18820.1 EGG02440.1 - 0.011 15.7 2.5 2.5 8.1 0.0 3.2 3 0 0 3 3 3 0 Bdellovibrio Beta-sandwich Rubi_NSP_C PF12601.8 EGG02440.1 - 0.092 12.9 0.0 33 4.7 0.0 3.2 3 0 0 3 3 3 0 Rubivirus non-structural protein GTP_cyclohydro2 PF00925.20 EGG02440.1 - 0.17 11.5 0.5 0.78 9.3 0.3 2.1 3 0 0 3 3 3 0 GTP cyclohydrolase II Sarcoglycan_1 PF04790.13 EGG02440.1 - 0.29 10.4 2.5 0.37 10.1 0.4 2.0 2 0 0 2 2 2 0 Sarcoglycan complex subunit protein Sulfate_transp PF00916.20 EGG02441.1 - 3e-83 279.7 13.1 4.1e-83 279.2 13.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGG02441.1 - 4.3e-19 68.3 0.0 7.5e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EGG02441.1 - 0.00077 19.8 0.1 0.0017 18.7 0.1 1.6 1 0 0 1 1 1 1 STAS domain DUF2417 PF10329.9 EGG02441.1 - 1.1 8.7 6.8 0.057 12.8 0.6 2.1 2 0 0 2 2 2 0 Region of unknown function (DUF2417) zf-RING_5 PF14634.6 EGG02442.1 - 2.2e-08 33.9 8.2 3.4e-08 33.3 8.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGG02442.1 - 0.0014 18.5 4.9 0.0029 17.4 4.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGG02442.1 - 0.0041 17.4 7.8 0.0068 16.7 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG02442.1 - 0.063 13.1 7.1 0.16 11.8 7.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG02442.1 - 0.11 12.4 8.7 0.2 11.6 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG02442.1 - 0.14 12.2 7.4 0.054 13.5 4.2 2.0 1 1 1 2 2 2 0 RING-type zinc-finger Ribosomal_S27e PF01667.17 EGG02442.1 - 0.17 11.6 2.7 0.39 10.4 2.7 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 DUF1272 PF06906.11 EGG02442.1 - 0.48 10.6 5.3 1.2 9.3 5.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zinc_ribbon_2 PF13240.6 EGG02442.1 - 0.55 10.0 2.2 1.1 9.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_4 PF15227.6 EGG02442.1 - 0.6 10.3 11.5 0.065 13.4 5.8 2.3 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-ribbon_3 PF13248.6 EGG02442.1 - 0.89 9.1 5.1 0.19 11.2 1.2 1.9 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 EGG02442.1 - 0.94 9.6 5.6 2.7 8.1 5.6 1.8 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EGG02442.1 - 0.95 9.6 2.9 2.3 8.4 2.9 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Cse1 PF08506.10 EGG02443.1 - 4.7e-138 460.0 3.2 7.1e-138 459.4 3.2 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 EGG02443.1 - 1.2e-116 389.8 0.7 3.1e-116 388.5 0.7 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 EGG02443.1 - 1.8e-12 47.0 3.7 2.3e-12 46.7 1.2 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGG02443.1 - 0.78 9.8 7.0 2.3 8.3 1.0 4.1 3 2 0 3 3 3 0 Exportin 1-like protein CxC1 PF18802.1 EGG02444.1 - 1.3e-30 105.6 0.5 2.9e-30 104.5 0.5 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG02444.1 - 5.2e-05 23.4 0.8 0.00013 22.0 0.8 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG02444.1 - 0.00079 19.2 1.2 0.0034 17.2 1.2 2.1 1 1 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases zf-3CxxC PF13695.6 EGG02444.1 - 0.14 12.7 11.7 0.14 12.6 1.5 3.2 3 0 0 3 3 3 0 Zinc-binding domain zf-3CxxC_2 PF17180.4 EGG02444.1 - 0.2 12.4 1.9 0.81 10.5 1.9 2.1 1 0 0 1 1 1 0 Zinc-binding domain Macoilin PF09726.9 EGG02445.1 - 2.1 6.8 10.3 2.4 6.6 10.3 1.1 1 0 0 1 1 1 0 Macoilin family EMP24_GP25L PF01105.24 EGG02446.1 - 0.17 11.8 0.1 0.35 10.8 0.0 1.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD ESSS PF10183.9 EGG02447.1 - 1 9.6 3.6 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1769 PF08588.10 EGG02451.1 - 0.0005 20.2 0.0 0.00064 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Nop14 PF04147.12 EGG02452.1 - 0.27 9.4 10.8 0.33 9.1 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family Roughex PF06020.11 EGG02452.1 - 0.3 10.2 6.9 0.4 9.7 6.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein CDC45 PF02724.14 EGG02452.1 - 7.3 4.7 14.1 9.4 4.4 14.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EGG02452.1 - 7.6 4.5 14.1 9.5 4.2 14.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi UNC-93 PF05978.16 EGG02453.1 - 6.4e-15 55.2 6.9 2.1e-14 53.5 6.9 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EGG02453.1 - 1.5e-12 47.2 29.2 1.5e-12 47.2 29.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1770 PF08589.10 EGG02455.1 - 1.1 10.3 8.3 0.28 12.2 2.4 2.8 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF1770) DUF2149 PF09919.9 EGG02456.1 - 7.2 6.9 5.9 8.6 6.7 5.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) YqzE PF14038.6 EGG02456.1 - 7.4 6.7 10.0 6.4 6.9 0.2 2.1 2 0 0 2 2 2 0 YqzE-like protein Skp1 PF01466.19 EGG02457.1 - 1.2e-27 95.8 0.2 2.1e-27 95.0 0.2 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EGG02457.1 - 3.8e-26 91.0 1.1 3.8e-26 91.0 1.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 EGG02457.1 - 0.0028 17.9 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain RPN6_N PF18055.1 EGG02457.1 - 0.056 13.8 0.1 3 8.2 0.0 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF4218 PF13960.6 EGG02458.1 - 0.00047 19.7 0.1 0.00072 19.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Rib_5-P_isom_A PF06026.14 EGG02460.1 - 5.2e-60 202.0 0.0 6.8e-60 201.6 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) OppC_N PF12911.7 EGG02461.1 - 0.5 10.4 3.2 8.3 6.5 0.0 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Myosin_head PF00063.21 EGG02462.1 - 7.4e-258 857.3 8.3 1.5e-217 724.1 0.9 2.8 3 0 0 3 3 3 2 Myosin head (motor domain) DIL PF01843.19 EGG02462.1 - 2.7e-26 91.9 2.4 2.7e-26 91.9 2.4 3.2 2 1 0 2 2 2 1 DIL domain IQ PF00612.27 EGG02462.1 - 0.00012 21.6 24.3 0.02 14.6 0.2 5.9 5 0 0 5 5 5 3 IQ calmodulin-binding motif AAA_16 PF13191.6 EGG02462.1 - 0.02 15.3 0.2 0.22 11.9 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EGG02462.1 - 0.022 15.0 0.2 0.18 12.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sec34 PF04136.15 EGG02462.1 - 0.23 11.3 11.8 0.091 12.6 3.0 2.9 2 0 0 2 2 2 0 Sec34-like family GrpE PF01025.19 EGG02462.1 - 0.65 9.6 13.6 0.28 10.8 1.9 2.7 2 0 0 2 2 2 0 GrpE IFT57 PF10498.9 EGG02462.1 - 4.3 6.2 20.9 6.7 5.6 18.8 2.4 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 NAD_binding_4 PF07993.12 EGG02464.1 - 3.7e-22 78.7 0.0 4.8e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGG02464.1 - 1.3e-12 47.7 0.0 2.4e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG02464.1 - 4.5e-07 29.6 0.0 8.8e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EGG02464.1 - 0.0017 18.3 0.0 0.0036 17.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGG02464.1 - 0.053 12.7 0.1 0.72 8.9 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein dsDNA_bind PF01984.20 EGG02465.1 - 1.6e-27 95.9 3.2 1.8e-27 95.8 3.2 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain BpuJI_N PF11564.8 EGG02465.1 - 0.15 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal CsbD PF05532.12 EGG02466.1 - 0.03 14.2 1.0 0.044 13.7 1.0 1.2 1 0 0 1 1 1 0 CsbD-like AAA_11 PF13086.6 EGG02467.1 - 2e-55 188.4 0.1 3.9e-55 187.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EGG02467.1 - 1.2e-54 185.0 0.0 1.8e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG02467.1 - 1.1e-13 51.4 0.0 9.4e-13 48.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG02467.1 - 1.8e-13 51.1 0.0 9.6e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EGG02467.1 - 3e-08 33.7 0.0 0.092 12.5 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EGG02467.1 - 9.2e-05 22.0 0.0 0.003 17.0 0.0 2.4 1 1 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.21 EGG02467.1 - 0.00014 21.5 0.0 0.00048 19.8 0.0 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 EGG02467.1 - 0.00058 19.9 0.0 0.0019 18.2 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 EGG02467.1 - 0.00098 19.5 0.2 0.041 14.3 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGG02467.1 - 0.0015 18.8 0.0 0.0079 16.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGG02467.1 - 0.0021 18.5 0.0 0.0047 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EGG02467.1 - 0.0025 16.9 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PIF1 PF05970.14 EGG02467.1 - 0.0028 16.9 0.0 0.16 11.1 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase UvrD_C_2 PF13538.6 EGG02467.1 - 0.0047 16.7 0.2 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain TrwB_AAD_bind PF10412.9 EGG02467.1 - 0.0055 15.7 0.0 0.0093 14.9 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Helicase_RecD PF05127.14 EGG02467.1 - 0.0088 15.9 0.2 0.089 12.6 0.2 2.4 1 1 0 1 1 1 1 Helicase DUF2075 PF09848.9 EGG02467.1 - 0.01 15.1 0.3 0.62 9.2 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 EGG02467.1 - 0.051 13.3 0.1 0.23 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGG02467.1 - 0.055 13.1 0.1 1.1 8.9 0.0 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 EGG02467.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EGG02467.1 - 0.096 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein PP2C PF00481.21 EGG02468.1 - 2e-06 27.7 0.0 2.7e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C Pox_Ag35 PF03286.14 EGG02469.1 - 0.41 10.4 17.8 0.044 13.6 11.9 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FXMRP1_C_core PF12235.8 EGG02469.1 - 6.2 7.5 23.5 1.1 9.9 18.8 2.0 2 1 0 2 2 2 0 Fragile X-related 1 protein core C terminal Nairovirus_M PF07948.11 EGG02472.1 - 0.021 13.1 1.3 0.035 12.3 1.3 1.3 1 0 0 1 1 1 0 Nairovirus M polyprotein-like DUF2207 PF09972.9 EGG02472.1 - 0.1 11.4 2.2 0.077 11.8 0.6 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Catalase PF00199.19 EGG02473.1 - 2.4e-140 468.0 0.1 2.7e-140 467.9 0.1 1.0 1 0 0 1 1 1 1 Catalase EIN3 PF04873.13 EGG02475.1 - 0.088 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Ethylene insensitive 3 Lipase_3 PF01764.25 EGG02476.1 - 5.3e-08 32.8 0.2 1.1e-07 31.9 0.2 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EGG02476.1 - 0.013 15.0 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) HTH_21 PF13276.6 EGG02477.1 - 0.00024 21.2 2.6 0.0051 16.9 0.5 2.4 2 0 0 2 2 2 1 HTH-like domain Clr5 PF14420.6 EGG02477.1 - 0.00059 20.0 0.0 0.2 11.9 0.0 2.4 2 0 0 2 2 2 2 Clr5 domain Arg_repressor PF01316.21 EGG02477.1 - 0.019 14.7 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_33 PF13592.6 EGG02477.1 - 0.025 14.2 1.2 3.4 7.4 0.1 3.3 3 0 0 3 3 3 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 EGG02477.1 - 0.086 13.1 0.5 2.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Transposase HTH_32 PF13565.6 EGG02477.1 - 0.13 12.8 5.6 8.8 7.0 0.5 3.2 3 1 1 4 4 4 0 Homeodomain-like domain PspA_IM30 PF04012.12 EGG02479.1 - 0.02 14.5 1.4 0.039 13.5 1.4 1.5 1 0 0 1 1 1 0 PspA/IM30 family BRE1 PF08647.11 EGG02479.1 - 0.073 13.2 3.7 1.8 8.7 0.5 2.8 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase XhlA PF10779.9 EGG02479.1 - 3 8.1 4.3 6.6 7.0 1.4 2.9 2 1 0 2 2 2 0 Haemolysin XhlA LRR_4 PF12799.7 EGG02481.1 - 0.0085 16.5 1.2 0.039 14.4 0.3 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Ufd2P_core PF10408.9 EGG02482.1 - 3.8e-12 45.6 0.1 4.7e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core ARTD15_N PF18084.1 EGG02485.1 - 0.056 13.7 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 ARTD15 N-terminal domain ABC_membrane PF00664.23 EGG02490.1 - 6.8e-14 52.2 3.7 8.8e-14 51.8 3.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGG02490.1 - 2.5e-12 47.5 0.1 4e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 ABC transporter Patched PF02460.18 EGG02490.1 - 0.056 11.5 0.3 0.27 9.3 0.3 1.8 2 0 0 2 2 2 0 Patched family Methyltransf_4 PF02390.17 EGG02492.1 - 0.035 13.6 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase FlaC_arch PF05377.11 EGG02495.1 - 0.51 10.8 2.0 1.1 9.7 1.2 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SURF4 PF02077.15 EGG02496.1 - 2.3e-90 302.9 4.4 2.6e-90 302.6 4.4 1.0 1 0 0 1 1 1 1 SURF4 family NMN_transporter PF04973.12 EGG02496.1 - 0.014 15.4 7.1 0.026 14.5 7.1 1.5 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter AhpC-TSA_2 PF13911.6 EGG02499.1 - 2.6e-11 43.6 0.0 5.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGG02499.1 - 0.0012 18.7 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Glyoxal_oxid_N PF07250.11 EGG02500.1 - 5.7e-36 123.9 0.2 6.5e-33 113.9 0.1 3.0 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EGG02500.1 - 8.4e-22 77.3 0.4 1.8e-21 76.2 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 EGG02500.1 - 0.0046 16.9 0.5 3.6 7.7 0.1 3.9 3 0 0 3 3 3 1 Galactose oxidase, central domain ATP19 PF11022.8 EGG02501.1 - 5.8e-23 81.0 0.1 6.6e-23 80.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit K COesterase PF00135.28 EGG02502.1 - 8.4e-73 246.0 0.0 2.6e-49 168.5 0.0 2.5 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG02502.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PolyA_pol PF01743.20 EGG02503.1 - 4e-28 98.4 0.4 6.2e-28 97.8 0.1 1.5 2 0 0 2 2 2 1 Poly A polymerase head domain Vps52 PF04129.12 EGG02504.1 - 8.8e-48 163.3 9.8 1.1e-30 106.9 0.1 3.6 4 0 0 4 4 4 3 Vps52 / Sac2 family CxC1 PF18802.1 EGG02506.1 - 2.7e-30 104.6 0.0 4.1e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG02506.1 - 8e-07 29.2 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG02506.1 - 0.078 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases L51_S25_CI-B8 PF05047.16 EGG02508.1 - 2.6e-10 40.1 0.1 3.9e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ThiF PF00899.21 EGG02509.1 - 8.3e-17 61.4 0.0 1.3e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family E1_4HB PF16191.5 EGG02509.1 - 0.053 13.7 0.2 1.3 9.3 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle zf-BED PF02892.15 EGG02510.1 - 0.00034 20.6 0.1 0.0032 17.4 0.1 2.6 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_4 PF13894.6 EGG02510.1 - 0.35 11.8 1.9 0.67 10.9 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2072 PF09845.9 EGG02510.1 - 0.63 10.3 5.8 0.16 12.2 2.0 1.9 2 0 0 2 2 2 0 Zn-ribbon containing protein CCDC53 PF10152.9 EGG02510.1 - 2.2 8.7 17.5 2.1 8.8 6.8 3.3 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Pex14_N PF04695.13 EGG02510.1 - 6 7.5 19.1 1.6 9.3 10.7 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EMG1 PF03587.14 EGG02514.1 - 2.1e-76 255.9 0.3 2.4e-76 255.7 0.3 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase AvrE_T3Es PF11725.8 EGG02514.1 - 0.16 9.2 0.1 0.2 8.8 0.1 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) MOR2-PAG1_N PF14222.6 EGG02515.1 - 6.4e-150 500.7 0.0 1.1e-149 500.0 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EGG02515.1 - 1.3e-65 221.8 0.1 3.4e-65 220.4 0.1 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EGG02515.1 - 2.9e-09 35.2 3.4 9.4e-08 30.2 0.5 3.1 3 0 0 3 3 3 2 Cell morphogenesis central region HEAT_2 PF13646.6 EGG02515.1 - 0.22 11.9 0.8 39 4.7 0.0 4.3 5 0 0 5 5 5 0 HEAT repeats zf-A20 PF01754.16 EGG02516.1 - 0.49 10.4 8.4 0.53 10.3 1.7 2.4 2 0 0 2 2 2 0 A20-like zinc finger RecR PF02132.15 EGG02516.1 - 1 9.0 6.5 0.59 9.7 4.7 1.5 2 0 0 2 2 2 0 RecR protein COesterase PF00135.28 EGG02518.1 - 2.4e-86 290.7 0.0 3.6e-86 290.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG02518.1 - 2e-05 24.5 0.2 0.012 15.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG02518.1 - 0.0032 17.0 0.2 0.0054 16.2 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Inositol_P PF00459.25 EGG02519.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Inositol monophosphatase family KxDL PF10241.9 EGG02520.1 - 1.9 8.9 14.1 0.084 13.2 6.5 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein Muted PF14942.6 EGG02520.1 - 3.6 7.9 26.8 5.6 7.3 8.2 2.6 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF2533 PF10752.9 EGG02520.1 - 3.7 8.0 8.5 0.11 12.9 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) DUF4419 PF14388.6 EGG02521.1 - 0.0091 15.4 0.1 0.021 14.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4419) KDZ PF18758.1 EGG02521.1 - 0.013 15.1 0.2 0.021 14.4 0.2 1.5 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase SNX17_FERM_C PF18116.1 EGG02521.1 - 0.033 14.3 0.6 0.62 10.2 0.1 2.6 2 0 0 2 2 2 0 Sorting Nexin 17 FERM C-terminal domain YfhO PF09586.10 EGG02521.1 - 0.14 10.3 0.8 0.22 9.7 0.8 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF313 PF03754.13 EGG02521.1 - 0.28 11.4 3.7 1.4 9.2 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF313) AAA_23 PF13476.6 EGG02521.1 - 0.62 10.5 10.5 0.19 12.2 7.7 1.5 2 0 0 2 2 2 0 AAA domain PBP1_TM PF14812.6 EGG02522.1 - 0.36 11.2 5.8 0.98 9.8 5.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 EGG02522.1 - 0.53 10.0 6.7 0.34 10.7 1.5 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CxC1 PF18802.1 EGG02524.1 - 5.7e-23 81.1 0.1 8e-23 80.6 0.1 1.2 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG02524.1 - 1.8e-09 37.7 0.0 2.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG02524.1 - 0.0053 16.6 0.0 0.0073 16.1 0.0 1.2 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases UPF0227 PF05728.12 EGG02525.1 - 0.14 12.1 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) HepII_C PF18675.1 EGG02529.1 - 0.023 14.8 0.1 0.25 11.5 0.0 2.4 2 1 1 3 3 3 0 Heparinase II C-terminal domain OspE PF02471.17 EGG02529.1 - 0.054 13.7 0.1 4.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Borrelia outer surface protein E Nic96 PF04097.14 EGG02530.1 - 9.8e-177 589.2 0.3 1.3e-176 588.7 0.3 1.1 1 0 0 1 1 1 1 Nup93/Nic96 LAMTOR PF15454.6 EGG02530.1 - 4.3 8.0 6.5 6.2 7.5 0.4 3.0 3 0 0 3 3 3 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Npa1 PF11707.8 EGG02533.1 - 3.5e-67 227.2 2.3 3.5e-67 227.2 2.3 2.9 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal DUF1804 PF08822.11 EGG02533.1 - 0.12 12.3 0.2 12 5.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1804) zf-C2H2_jaz PF12171.8 EGG02534.1 - 2.7e-05 24.3 0.8 5e-05 23.5 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG02534.1 - 0.00013 22.2 1.8 0.00024 21.4 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGG02534.1 - 0.026 14.8 0.0 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EGG02534.1 - 0.03 14.8 1.9 0.057 13.9 1.9 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 EGG02534.1 - 0.045 13.4 0.4 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 EGG02534.1 - 0.071 14.0 0.5 0.15 13.0 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Atg14 PF10186.9 EGG02534.1 - 0.077 12.1 19.2 0.28 10.2 3.8 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PTPRCAP PF15713.5 EGG02534.1 - 0.76 10.1 9.0 5.2 7.3 0.7 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Selenoprotein_S PF06936.11 EGG02534.1 - 2.5 7.9 16.0 0.2 11.5 6.2 2.2 2 0 0 2 2 2 0 Selenoprotein S (SelS) DUF2284 PF10050.9 EGG02534.1 - 3.2 7.5 5.2 0.83 9.4 0.5 2.2 2 1 0 2 2 2 0 Predicted metal-binding protein (DUF2284) MACPF PF01823.19 EGG02535.1 - 0.042 13.9 1.1 0.22 11.6 0.5 2.3 2 1 0 2 2 2 0 MAC/Perforin domain Pox_Ag35 PF03286.14 EGG02535.1 - 0.069 12.9 6.0 0.15 11.8 6.0 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4207 PF13904.6 EGG02535.1 - 0.074 12.7 7.8 0.42 10.3 7.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) Kei1 PF08552.11 EGG02536.1 - 3.3e-50 170.6 2.5 4.6e-50 170.1 2.5 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF5345 PF17280.2 EGG02536.1 - 0.026 14.5 4.4 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5345) AhpC-TSA_2 PF13911.6 EGG02538.1 - 2.5e-09 37.2 0.0 4.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGG02538.1 - 0.0055 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family ThiF PF00899.21 EGG02539.1 - 1.8e-66 224.0 0.0 2.4e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EGG02539.1 - 9.7e-13 48.6 0.2 6.2e-08 32.9 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site Sacchrp_dh_NADP PF03435.18 EGG02539.1 - 9.2e-05 22.7 0.2 0.00032 20.9 0.2 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EGG02539.1 - 0.00049 20.5 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EGG02539.1 - 0.00086 19.4 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EGG02539.1 - 0.13 12.8 0.0 0.4 11.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF5438 PF17506.2 EGG02539.1 - 0.29 11.5 2.1 0.27 11.6 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5438) RNA_pol_Rpb2_6 PF00562.28 EGG02540.1 - 1.9e-108 363.0 0.0 7.1e-108 361.1 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGG02540.1 - 1.1e-36 126.3 0.0 1.8e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EGG02540.1 - 8.7e-28 96.3 0.0 1.9e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EGG02540.1 - 2.7e-20 72.8 0.0 4.2e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EGG02540.1 - 3.1e-20 71.9 0.0 6.6e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 EGG02540.1 - 4.4e-18 65.5 0.4 5.3e-16 58.8 0.4 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Cation_ATPase_C PF00689.21 EGG02541.1 - 0.03 14.0 0.0 0.071 12.8 0.0 1.7 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF3611 PF12263.8 EGG02541.1 - 0.53 10.2 4.1 0.4 10.6 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) DUF4149 PF13664.6 EGG02541.1 - 3.8 7.9 6.3 7.4 7.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) CAP59_mtransfer PF11735.8 EGG02542.1 - 1.4e-14 54.4 0.0 2.2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 FAM124 PF15067.6 EGG02542.1 - 0.089 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 FAM124 family DUF702 PF05142.12 EGG02543.1 - 0.036 14.5 4.0 0.07 13.6 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) CARMIL_C PF16000.5 EGG02543.1 - 1.5 8.3 12.7 0.15 11.7 3.3 2.2 2 0 0 2 2 2 0 CARMIL C-terminus Mg_trans_NIPA PF05653.14 EGG02544.1 - 2.5e-107 358.4 15.9 3.1e-107 358.1 15.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EGG02544.1 - 6.6e-06 26.3 4.0 6.6e-06 26.3 4.0 3.9 3 1 0 3 3 3 1 EamA-like transporter family Acyl_transf_3 PF01757.22 EGG02544.1 - 0.11 11.5 18.4 5.3 6.0 14.7 2.3 1 1 0 1 1 1 0 Acyltransferase family La PF05383.17 EGG02546.1 - 1.2e-19 70.1 0.1 2.3e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 La domain Zip PF02535.22 EGG02546.1 - 3.1 6.9 7.6 7.8 5.6 7.6 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter Oxidored-like PF09791.9 EGG02547.1 - 2.8e-16 58.9 3.2 5.5e-16 57.9 3.2 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal ATP_sub_h PF10775.9 EGG02547.1 - 0.078 13.0 0.1 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 ATP synthase complex subunit h vATP-synt_E PF01991.18 EGG02548.1 - 1.3e-58 197.7 14.6 1.5e-58 197.5 14.6 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit SCAN PF02023.17 EGG02548.1 - 0.014 15.1 0.1 0.041 13.7 0.1 1.7 1 0 0 1 1 1 0 SCAN domain Radial_spoke_3 PF06098.11 EGG02548.1 - 0.31 10.3 12.9 0.43 9.8 12.9 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 SurA_N PF09312.11 EGG02548.1 - 0.34 11.0 6.6 0.26 11.4 1.7 2.5 1 1 1 2 2 2 0 SurA N-terminal domain UPF0449 PF15136.6 EGG02548.1 - 0.62 10.6 5.8 0.3 11.6 3.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Phlebovirus_NSM PF07246.11 EGG02548.1 - 1.1 8.6 10.2 1.6 8.1 10.2 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M PRP1_N PF06424.12 EGG02548.1 - 3.5 8.0 7.4 9.5 6.6 7.4 1.7 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF883 PF05957.13 EGG02548.1 - 8.2 7.1 7.7 3.5 8.3 1.1 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) ALG3 PF05208.13 EGG02550.1 - 4.5e-41 141.5 20.9 3.8e-26 92.4 13.5 2.6 1 1 1 2 2 2 2 ALG3 protein BPD_transp_1 PF00528.22 EGG02550.1 - 4.4 7.0 8.3 0.61 9.8 0.9 2.4 2 1 1 3 3 3 0 Binding-protein-dependent transport system inner membrane component Thioredoxin_12 PF18400.1 EGG02552.1 - 0.016 15.0 0.1 0.021 14.7 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain RICTOR_M PF14666.6 EGG02552.1 - 0.12 12.1 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain DUF4218 PF13960.6 EGG02555.1 - 4e-05 23.2 0.1 7e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) MEA1 PF06910.11 EGG02555.1 - 0.14 12.8 0.1 13 6.4 0.0 2.3 2 0 0 2 2 2 0 Male enhanced antigen 1 (MEA1) PdaC PF13739.6 EGG02556.1 - 0.095 13.7 1.0 0.35 11.9 0.1 2.2 2 0 0 2 2 2 0 Deacetylase PdaC TMCO5 PF14992.6 EGG02556.1 - 0.38 10.3 9.7 0.015 14.9 3.8 1.6 2 0 0 2 2 2 0 TMCO5 family Syntaxin-6_N PF09177.11 EGG02556.1 - 0.78 10.3 4.3 0.26 11.8 0.7 2.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 EGG02556.1 - 4.3 6.6 6.2 3.9 6.7 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GAGE PF05831.11 EGG02557.1 - 0.023 15.2 0.6 0.023 15.2 0.6 2.6 2 0 0 2 2 2 0 GAGE protein MCM6_C PF18263.1 EGG02557.1 - 0.024 14.8 0.0 0.076 13.3 0.0 1.8 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain GP57 PF17594.2 EGG02557.1 - 0.099 12.4 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 SesA PF17107.5 EGG02558.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4218 PF13960.6 EGG02561.1 - 3.3e-06 26.7 0.4 6.8e-06 25.7 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) CAF1A PF12253.8 EGG02561.1 - 0.31 11.2 4.3 0.092 12.9 0.6 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A DZF PF07528.14 EGG02563.1 - 0.052 13.2 0.1 0.067 12.8 0.1 1.1 1 0 0 1 1 1 0 DZF domain Seryl_tRNA_N PF02403.22 EGG02564.1 - 0.0022 18.2 1.9 0.0065 16.7 1.9 1.8 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.7 EGG02564.1 - 0.0063 16.7 13.7 0.039 14.1 1.8 2.5 1 1 1 2 2 2 2 Tropomyosin like DUF4407 PF14362.6 EGG02564.1 - 0.019 14.3 0.5 0.032 13.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PHM7_cyt PF14703.6 EGG02564.1 - 0.042 14.1 2.9 0.049 13.9 0.2 2.3 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter NPV_P10 PF05531.12 EGG02564.1 - 0.065 13.7 6.9 0.13 12.8 1.2 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 EGG02564.1 - 0.09 12.1 7.4 0.17 11.3 7.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 EGG02564.1 - 0.19 11.8 8.3 0.052 13.6 1.9 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 EGG02564.1 - 0.31 11.5 4.0 0.47 10.9 2.7 2.0 1 1 1 2 2 2 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 EGG02564.1 - 0.57 10.3 8.5 0.7 10.0 5.7 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pex14_N PF04695.13 EGG02564.1 - 4.1 8.1 8.6 18 6.0 2.6 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1664 PF07889.12 EGG02564.1 - 5.8 7.0 7.8 2.2 8.3 4.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Csm1_N PF18504.1 EGG02564.1 - 6.4 7.2 9.7 38 4.7 2.8 3.6 1 1 1 2 2 2 0 Csm1 N-terminal domain FlaC_arch PF05377.11 EGG02564.1 - 7.8 7.0 6.2 8.8 6.8 1.7 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Mucin PF01456.17 EGG02566.1 - 1.2 9.2 8.4 2.5 8.1 8.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SH3_5 PF08460.10 EGG02568.1 - 0.044 13.9 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain HeLo PF14479.6 EGG02569.1 - 0.041 13.7 0.3 0.064 13.1 0.3 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF745 PF05335.13 EGG02569.1 - 0.26 11.0 2.8 2 8.1 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF745) PilM_2 PF11104.8 EGG02570.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; zf-RING_2 PF13639.6 EGG02571.1 - 4e-07 30.3 8.0 7.9e-07 29.3 8.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG02571.1 - 0.0019 18.2 2.1 0.0019 18.2 2.1 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG02571.1 - 0.014 15.3 9.2 0.06 13.3 9.1 2.0 1 1 1 2 2 2 0 zinc-RING finger domain Zn-C2H2_12 PF18112.1 EGG02571.1 - 0.037 14.5 3.9 0.71 10.4 0.1 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_9 PF14369.6 EGG02571.1 - 0.1 12.9 2.9 2.3 8.6 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon zf-C3HC4_4 PF15227.6 EGG02571.1 - 0.1 12.8 5.4 0.23 11.7 5.4 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGG02571.1 - 0.11 12.3 7.8 0.23 11.3 7.8 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EGG02571.1 - 0.22 11.4 5.7 0.63 9.9 5.5 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Endonuclease_7 PF02945.15 EGG02571.1 - 0.34 10.8 5.0 0.58 10.1 5.0 1.3 1 0 0 1 1 1 0 Recombination endonuclease VII zf-C3HC4 PF00097.25 EGG02571.1 - 0.57 10.1 6.9 1.1 9.2 6.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG02571.1 - 0.64 9.9 9.3 3.6 7.5 9.4 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG02571.1 - 1.2 9.0 9.2 4.5 7.2 0.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EGG02571.1 - 1.4 9.1 5.7 3.8 7.7 5.7 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Alpha_kinase PF02816.18 EGG02572.1 - 3.2e-12 46.9 0.1 6.9e-12 45.9 0.1 1.5 1 1 0 1 1 1 1 Alpha-kinase family Rubredoxin_2 PF18073.1 EGG02572.1 - 0.85 9.4 4.4 0.35 10.6 1.6 1.9 2 0 0 2 2 2 0 Rubredoxin metal binding domain Lipase_3 PF01764.25 EGG02573.1 - 3.1e-08 33.6 0.2 7e-08 32.4 0.2 1.7 1 1 0 1 1 1 1 Lipase (class 3) MADF_DNA_bdg PF10545.9 EGG02573.1 - 0.083 13.2 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MSP1b PF03429.13 EGG02573.1 - 0.11 10.5 0.1 0.14 10.2 0.1 1.1 1 0 0 1 1 1 0 Major surface protein 1B Glyco_transf_90 PF05686.12 EGG02574.1 - 3.3e-18 65.8 0.6 8.1e-16 57.9 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 DUF3827 PF12877.7 EGG02577.1 - 0.17 10.2 16.8 0.2 10.0 16.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CDC45 PF02724.14 EGG02577.1 - 0.37 9.0 9.2 0.4 8.9 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4337 PF14235.6 EGG02577.1 - 3.5 7.7 4.8 4.6 7.3 4.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Paramyxo_ncap PF00973.19 EGG02577.1 - 7.6 5.3 9.7 9.2 5.1 9.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Baculo_PEP_C PF04513.12 EGG02578.1 - 0.037 14.1 0.1 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.6 EGG02578.1 - 0.097 12.1 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) RTX_C PF08339.10 EGG02578.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 RTX C-terminal domain DNA_primase_S PF01896.19 EGG02580.1 - 4e-16 59.6 0.0 4.3e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 DNA primase small subunit Peptidase_C78 PF07910.13 EGG02582.1 - 1.3e-42 145.7 0.0 2.4e-33 115.4 0.0 2.4 1 1 1 2 2 2 2 Peptidase family C78 PGK PF00162.19 EGG02583.1 - 8.2e-149 495.7 2.0 9.8e-149 495.4 2.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF2141 PF09912.9 EGG02583.1 - 0.039 13.9 0.1 0.092 12.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) adh_short PF00106.25 EGG02584.1 - 2.4e-27 95.7 0.0 3e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG02584.1 - 6.5e-26 91.3 0.0 8.3e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG02584.1 - 2.7e-08 33.9 0.2 4.8e-08 33.1 0.1 1.5 1 1 1 2 2 2 1 KR domain UPRTase PF14681.6 EGG02585.1 - 2.1e-60 203.7 0.0 2.3e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGG02585.1 - 0.0028 17.2 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DBP PF12361.8 EGG02586.1 - 0.02 14.8 0.3 0.028 14.3 0.3 1.1 1 0 0 1 1 1 0 Duffy-antigen binding protein NAM-associated PF14303.6 EGG02586.1 - 0.039 14.7 0.9 0.055 14.2 0.9 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SlyX PF04102.12 EGG02587.1 - 0.017 15.7 3.3 0.017 15.7 3.3 2.0 2 0 0 2 2 2 0 SlyX Laminin_II PF06009.12 EGG02587.1 - 0.34 10.9 7.6 2.4 8.1 2.2 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF16 PF01519.16 EGG02587.1 - 2.8 8.5 14.5 0.18 12.3 7.8 2.3 2 1 1 3 3 3 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 EGG02587.1 - 4.9 7.6 9.1 1.5 9.2 1.6 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 EGG02587.1 - 7.9 6.5 16.2 1.3 9.0 3.2 3.0 2 1 0 3 3 3 0 Prefoldin subunit Pox_F11 PF04943.12 EGG02588.1 - 0.0018 17.4 0.2 0.0024 17.0 0.2 1.1 1 0 0 1 1 1 1 Poxvirus F11 protein Prominin PF05478.11 EGG02588.1 - 0.04 11.9 1.7 0.049 11.6 1.7 1.0 1 0 0 1 1 1 0 Prominin FliJ PF02050.16 EGG02588.1 - 0.2 11.9 5.1 0.23 11.7 4.3 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein Sigma70_ner PF04546.13 EGG02589.1 - 0.19 11.6 3.1 0.59 10.0 0.8 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Hid1 PF12722.7 EGG02591.1 - 0.15 10.2 14.3 0.21 9.7 14.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein COesterase PF00135.28 EGG02595.1 - 0.0062 15.5 0.1 0.0065 15.4 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Lipase_GDSL_2 PF13472.6 EGG02596.1 - 0.0066 16.9 0.2 0.008 16.6 0.2 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family W2 PF02020.18 EGG02597.1 - 1.8e-12 47.2 0.5 4.1e-12 46.1 0.5 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EGG02597.1 - 3.3e-11 42.4 10.5 6.1e-05 22.6 3.4 3.9 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EGG02597.1 - 0.0051 15.0 4.7 0.0089 14.2 4.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EGG02597.1 - 0.037 13.0 2.2 0.12 11.3 2.2 1.8 1 1 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 EGG02597.1 - 1.9 8.3 16.2 2.4 8.0 2.6 4.0 1 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase APC1_C PF18122.1 EGG02598.1 - 1.1e-31 110.0 0.2 3.7e-31 108.3 0.2 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 EGG02598.1 - 1.7e-11 44.8 0.0 1.7e-11 44.8 0.0 4.6 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EGG02598.1 - 4.9 7.8 14.6 1.1 9.9 0.1 5.0 5 0 0 5 5 5 0 Proteasome/cyclosome repeat RTC_insert PF05189.13 EGG02600.1 - 0.064 13.8 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain p450 PF00067.22 EGG02601.1 - 1.9e-58 198.4 0.0 2.5e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SHMT PF00464.19 EGG02602.1 - 2.6e-06 26.3 0.0 2.8e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase GFA PF04828.14 EGG02603.1 - 6e-09 36.1 4.4 2.4e-08 34.2 1.5 2.9 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HECT_2 PF09814.9 EGG02603.1 - 0.014 14.3 0.1 0.014 14.3 0.1 2.0 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Sgf11 PF08209.11 EGG02603.1 - 2.3 7.9 9.4 3 7.5 3.5 3.0 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) GFA PF04828.14 EGG02604.1 - 2e-09 37.7 2.1 8.1e-09 35.7 0.6 2.4 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HECT_2 PF09814.9 EGG02604.1 - 0.0041 16.0 2.6 0.0071 15.2 2.6 1.5 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RIG-I_C-RD PF11648.8 EGG02604.1 - 0.13 12.5 4.2 0.84 9.9 0.4 2.2 1 1 0 2 2 2 0 C-terminal domain of RIG-I Sgf11 PF08209.11 EGG02604.1 - 0.24 11.0 5.5 0.75 9.4 1.5 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_4 PF13717.6 EGG02604.1 - 0.34 10.9 0.1 0.34 10.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-HIT PF04438.16 EGG02605.1 - 6.6e-08 32.3 11.2 1e-07 31.7 11.2 1.3 1 0 0 1 1 1 1 HIT zinc finger TYW3 PF02676.14 EGG02605.1 - 0.019 14.4 0.8 0.019 14.4 0.8 1.0 1 0 0 1 1 1 0 Methyltransferase TYW3 PolC_DP2 PF03833.13 EGG02605.1 - 0.81 7.5 6.8 0.77 7.6 6.8 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 adh_short PF00106.25 EGG02611.1 - 1.5e-29 102.9 0.0 5.9e-28 97.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG02611.1 - 7.7e-16 58.4 0.0 2.3e-14 53.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG02611.1 - 3e-06 27.3 0.0 5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG02611.1 - 0.023 14.2 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADC PF06314.11 EGG02612.1 - 0.0061 16.1 0.0 0.0092 15.6 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Snf7 PF03357.21 EGG02614.1 - 5.2e-20 71.7 19.1 9.2e-20 70.9 19.1 1.4 1 0 0 1 1 1 1 Snf7 DUF948 PF06103.11 EGG02614.1 - 0.033 14.4 2.1 0.033 14.4 2.1 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) BAG PF02179.16 EGG02614.1 - 0.16 12.4 3.5 0.14 12.7 0.6 2.3 1 1 0 2 2 2 0 BAG domain FTZ PF03867.14 EGG02614.1 - 0.88 9.1 3.3 0.42 10.1 0.2 2.0 2 1 1 3 3 3 0 Fushi tarazu (FTZ), N-terminal region Syntaxin-6_N PF09177.11 EGG02614.1 - 3.8 8.1 19.4 0.98 10.0 2.6 3.6 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Tweety PF04906.13 EGG02614.1 - 5 5.7 7.7 2.6 6.6 5.3 1.7 1 1 1 2 2 2 0 Tweety SGL PF08450.12 EGG02615.1 - 4.3e-06 26.5 0.0 8.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EGG02615.1 - 0.00015 21.8 0.0 0.00037 20.6 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 EGG02615.1 - 0.059 13.6 0.0 0.15 12.2 0.0 1.8 1 1 0 1 1 1 0 Arylesterase Fungal_trans PF04082.18 EGG02616.1 - 1.3e-40 139.2 3.2 1.3e-40 139.2 3.2 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EGG02616.1 - 0.0016 18.8 2.3 0.0016 18.8 2.3 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGG02616.1 - 0.0016 18.8 0.6 0.0016 18.8 0.6 4.4 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG02616.1 - 0.073 13.9 0.5 0.073 13.9 0.5 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger PP2 PF14299.6 EGG02618.1 - 0.11 12.6 0.0 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Phloem protein 2 Zn_clus PF00172.18 EGG02619.1 - 2.9e-06 27.3 6.0 6.6e-06 26.2 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CFEM PF05730.11 EGG02620.1 - 2e-12 47.0 4.7 3.8e-12 46.1 4.7 1.5 1 0 0 1 1 1 1 CFEM domain NAM-associated PF14303.6 EGG02621.1 - 6e-16 59.6 8.9 6e-16 59.6 8.9 2.6 2 1 0 2 2 2 1 No apical meristem-associated C-terminal domain EccE PF11203.8 EGG02621.1 - 0.028 14.7 0.1 0.042 14.2 0.1 1.5 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE CPSF73-100_C PF11718.8 EGG02623.1 - 1e-46 159.3 0.1 1.6e-46 158.6 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EGG02623.1 - 5.1e-29 100.8 0.0 1.1e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EGG02623.1 - 5.2e-19 68.4 0.1 9.4e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EGG02623.1 - 3.5e-17 63.1 0.0 6.5e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EGG02623.1 - 1.5e-14 53.6 0.0 3.3e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EGG02623.1 - 4.8e-08 32.8 0.1 1.3e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGG02623.1 - 5.6e-06 26.3 0.2 3.8e-05 23.6 0.1 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain RILP PF11461.8 EGG02623.1 - 0.11 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein TPT PF03151.16 EGG02624.1 - 1.2e-17 64.3 24.0 3.1e-17 62.9 24.0 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family FAM60A PF15396.6 EGG02624.1 - 0.12 12.4 0.1 0.3 11.1 0.1 1.5 1 1 0 1 1 1 0 Protein Family FAM60A Gemini_mov PF01708.16 EGG02624.1 - 0.19 11.5 1.2 27 4.6 0.9 3.1 2 0 0 2 2 2 0 Geminivirus putative movement protein Angiomotin_C PF12240.8 EGG02624.1 - 0.44 10.1 0.0 0.44 10.1 0.0 2.2 2 1 0 2 2 2 0 Angiomotin C terminal DivIC PF04977.15 EGG02625.1 - 0.005 16.6 19.7 0.0097 15.7 4.3 3.8 1 1 2 4 4 4 2 Septum formation initiator GIT1_C PF12205.8 EGG02625.1 - 0.026 14.6 1.6 0.026 14.6 1.6 2.5 1 1 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term FUSC PF04632.12 EGG02625.1 - 0.055 12.0 1.0 0.091 11.3 0.1 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family M3 PF09213.10 EGG02625.1 - 0.15 10.7 0.2 0.25 10.0 0.2 1.3 1 0 0 1 1 1 0 M3 CENP-H PF05837.12 EGG02625.1 - 0.18 12.2 28.6 0.81 10.1 7.4 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF4200 PF13863.6 EGG02625.1 - 0.27 11.7 25.5 0.31 11.4 4.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 EGG02625.1 - 0.43 10.6 32.4 0.16 12.0 13.2 2.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 EGG02625.1 - 0.6 10.6 32.5 0.48 11.0 14.7 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region Scaffolding_pro PF11418.8 EGG02625.1 - 0.65 10.6 9.0 0.12 13.0 2.8 2.7 1 1 1 2 2 2 0 Phi29 scaffolding protein bZIP_1 PF00170.21 EGG02625.1 - 0.93 9.6 21.2 2.6 8.2 2.1 4.5 2 2 1 4 4 4 0 bZIP transcription factor BRE1 PF08647.11 EGG02625.1 - 1 9.5 28.1 0.24 11.5 11.5 2.7 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase ATPase PF06745.13 EGG02625.1 - 2 7.7 6.2 2.1 7.7 1.3 2.2 1 1 1 2 2 2 0 KaiC DUF2730 PF10805.8 EGG02625.1 - 2.5 8.3 14.2 0.84 9.8 1.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Spc7 PF08317.11 EGG02625.1 - 3.1 6.6 29.8 1.2 8.0 8.0 2.7 1 1 2 3 3 3 0 Spc7 kinetochore protein Tup_N PF08581.10 EGG02625.1 - 3.3 8.1 21.1 7.5 6.9 5.2 4.1 1 1 3 4 4 4 0 Tup N-terminal RasGAP_C PF03836.15 EGG02625.1 - 3.8 7.7 27.8 0.22 11.7 4.1 3.4 1 1 1 2 2 1 0 RasGAP C-terminus Mod_r PF07200.13 EGG02625.1 - 4.3 7.4 34.1 1.2 9.2 3.7 3.3 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ZapB PF06005.12 EGG02625.1 - 7.6 7.1 26.2 20 5.7 6.4 4.1 1 1 1 2 2 2 0 Cell division protein ZapB FlaC_arch PF05377.11 EGG02625.1 - 8 6.9 15.6 3.9 7.9 2.2 4.5 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) ROQ_II PF18386.1 EGG02627.1 - 0.053 13.3 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Roquin II domain DAO PF01266.24 EGG02628.1 - 1.3e-23 84.2 0.0 1e-17 64.8 0.0 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGG02628.1 - 0.0023 18.1 0.1 0.0067 16.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG02628.1 - 0.0058 15.9 0.0 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGG02628.1 - 0.054 12.6 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Glyco_hydro_63 PF03200.16 EGG02629.1 - 1.5e-170 568.2 0.7 1.2e-169 565.3 0.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EGG02629.1 - 7.4e-77 258.5 0.1 6e-76 255.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EGG02629.1 - 7.1e-06 25.1 0.9 1.7e-05 23.8 0.2 1.8 2 0 0 2 2 2 1 Trehalase Bac_rhamnosid6H PF17389.2 EGG02629.1 - 0.024 13.9 0.0 0.053 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain PQ-loop PF04193.14 EGG02630.1 - 5.5e-37 125.4 14.5 4.1e-19 68.1 0.8 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 EGG02630.1 - 0.00028 20.9 4.7 0.041 13.9 0.5 3.1 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange HEV_ORF1 PF02444.16 EGG02631.1 - 0.071 13.7 1.4 0.72 10.4 0.1 2.2 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) DUF488 PF04343.13 EGG02631.1 - 0.78 10.3 6.0 0.72 10.4 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF488 SLC12 PF03522.15 EGG02632.1 - 0.051 12.6 0.1 0.13 11.3 0.1 1.6 1 0 0 1 1 1 0 Solute carrier family 12 Bacteriocin_IIi PF11758.8 EGG02634.1 - 0.02 14.7 0.2 0.05 13.4 0.2 1.8 1 1 0 1 1 1 0 Aureocin-like type II bacteriocin CENP-T_C PF15511.6 EGG02637.1 - 0.086 13.0 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold CdhD PF03599.16 EGG02640.1 - 0.14 10.9 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit ecTbetaR2 PF08917.10 EGG02642.1 - 0.032 14.2 0.5 0.066 13.2 0.5 1.5 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain SAP PF02037.27 EGG02643.1 - 4.3e-06 26.3 0.3 0.072 12.9 0.2 3.5 3 0 0 3 3 3 2 SAP domain HeH PF12949.7 EGG02643.1 - 0.0029 17.3 1.4 3 7.6 0.0 4.5 5 0 0 5 5 5 1 HeH/LEM domain PHA_synth_III_E PF09712.10 EGG02643.1 - 0.096 11.8 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) FlaC_arch PF05377.11 EGG02643.1 - 2.4 8.6 6.5 0.71 10.3 3.0 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FXMR_C2 PF16098.5 EGG02644.1 - 0.31 11.6 2.4 0.23 12.0 0.5 1.8 2 0 0 2 2 2 0 Fragile X-related mental retardation protein C-terminal region 2 Mucin PF01456.17 EGG02645.1 - 0.75 9.8 45.9 0.1 12.6 18.4 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Retrotran_gag_2 PF14223.6 EGG02646.1 - 0.00056 19.6 0.2 0.0027 17.4 0.1 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DPBB_1 PF03330.18 EGG02647.1 - 0.0044 17.3 0.2 0.018 15.3 0.2 2.0 2 0 0 2 2 2 1 Lytic transglycolase RXT2_N PF08595.11 EGG02647.1 - 0.016 15.3 1.8 0.023 14.7 1.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 EGG02647.1 - 0.026 14.9 10.0 0.047 14.1 10.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AP-5_subunit_s1 PF15001.6 EGG02647.1 - 0.047 13.7 0.2 0.072 13.1 0.2 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF4611 PF15387.6 EGG02647.1 - 0.051 13.8 3.1 0.1 12.9 3.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 EGG02647.1 - 8.7 4.3 7.5 11 3.9 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Hist_deacetyl PF00850.19 EGG02648.1 - 5.2e-51 174.0 0.0 7.6e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain tRNA-synt_1 PF00133.22 EGG02652.1 - 2.1e-13 49.4 0.0 2.4e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGG02652.1 - 0.02 13.6 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) NAP PF00956.18 EGG02653.1 - 3.8e-66 223.0 5.2 4.9e-52 176.8 2.9 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.12 EGG02653.1 - 0.021 14.5 13.4 0.24 11.1 6.4 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pex14_N PF04695.13 EGG02657.1 - 0.13 12.9 3.0 0.27 11.9 3.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Per1 PF04080.13 EGG02659.1 - 8.2e-15 55.3 0.0 8.2e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Per1-like family Biotin_lipoyl PF00364.22 EGG02661.1 - 5.5e-14 51.8 3.2 1e-13 50.9 3.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGG02661.1 - 0.00017 21.4 4.1 0.0057 16.4 0.3 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 EGG02661.1 - 0.00042 21.0 0.1 0.97 10.2 0.0 2.4 2 0 0 2 2 2 2 HlyD family secretion protein NQRA PF05896.11 EGG02661.1 - 0.0072 15.8 0.3 0.0097 15.4 0.3 1.2 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 EGG02661.1 - 0.014 15.4 0.6 0.023 14.6 0.6 1.5 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 EGG02661.1 - 0.014 14.6 0.5 0.045 13.0 0.2 1.9 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 EGG02661.1 - 0.023 14.6 0.9 0.11 12.3 0.2 1.9 1 1 1 2 2 2 0 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 EGG02661.1 - 0.09 12.5 0.1 0.78 9.5 0.1 2.2 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Cwf_Cwc_15 PF04889.12 EGG02663.1 - 0.0018 18.1 3.3 0.002 17.9 3.3 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SPT2 PF08243.11 EGG02663.1 - 0.75 10.3 6.8 0.97 10.0 6.5 1.3 1 1 0 1 1 1 0 SPT2 chromatin protein DnaJ PF00226.31 EGG02664.1 - 1.3e-18 66.9 0.1 6.3e-18 64.7 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 EGG02664.1 - 0.00022 21.1 1.1 0.0058 16.7 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG02664.1 - 0.0032 17.2 0.3 0.57 10.1 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG02664.1 - 0.013 16.0 1.4 0.51 11.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGG02664.1 - 0.047 14.2 0.3 0.58 10.7 0.3 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGG02664.1 - 0.1 13.2 1.2 0.5 11.1 0.5 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG02664.1 - 0.12 13.2 0.3 3.3 8.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Band_7 PF01145.25 EGG02665.1 - 9.1e-14 51.9 3.8 1.5e-13 51.2 3.8 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family Alpha_GJ PF03229.13 EGG02666.1 - 4.5 7.9 6.2 0.19 12.3 0.4 1.7 2 0 0 2 2 2 0 Alphavirus glycoprotein J Retrotran_gag_2 PF14223.6 EGG02667.1 - 0.0037 16.9 0.0 0.0065 16.1 0.0 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type CDP-OH_P_transf PF01066.21 EGG02667.1 - 0.065 14.0 0.2 0.17 12.7 0.2 1.9 2 1 0 2 2 2 0 CDP-alcohol phosphatidyltransferase NARP1 PF12569.8 EGG02670.1 - 2.9e-40 138.7 0.0 3.2e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 EGG02670.1 - 0.00079 20.0 1.0 0.0036 18.0 0.6 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG02670.1 - 0.038 13.8 0.1 0.087 12.7 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG02670.1 - 0.058 13.5 1.5 0.073 13.2 0.2 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG02670.1 - 0.19 12.4 0.9 37 5.3 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 EGG02671.1 - 1.7e-05 24.0 0.1 1.8e-05 23.9 0.1 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 Myb_DNA-bind_3 PF12776.7 EGG02672.1 - 0.0004 21.3 0.0 0.00076 20.4 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain ParBc PF02195.18 EGG02673.1 - 0.44 10.9 1.9 8.2 6.8 0.1 3.3 3 0 0 3 3 3 0 ParB-like nuclease domain T3SS_needle_E PF08988.10 EGG02675.1 - 0.052 13.7 0.7 6.5 7.0 0.2 2.5 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle MTABC_N PF16185.5 EGG02675.1 - 0.06 12.8 0.1 0.091 12.2 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region MLVIN_C PF18697.1 EGG02677.1 - 0.0019 18.2 0.4 0.011 15.8 0.0 2.4 2 0 0 2 2 2 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Asp_protease_2 PF13650.6 EGG02677.1 - 0.0036 17.9 0.0 0.017 15.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 EGG02677.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease GRDA PF04723.14 EGG02677.1 - 0.15 11.9 0.0 0.36 10.6 0.0 1.6 2 0 0 2 2 2 0 Glycine reductase complex selenoprotein A Levi_coat PF01819.17 EGG02677.1 - 0.15 12.1 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Levivirus coat protein HSCB_C PF07743.13 EGG02677.1 - 4.1 8.0 7.2 34 5.0 0.0 2.6 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain NMT1_2 PF13379.6 EGG02678.1 - 0.11 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 NMT1-like family Transferase PF02458.15 EGG02679.1 - 0.054 12.1 0.2 0.066 11.8 0.2 1.1 1 0 0 1 1 1 0 Transferase family C2 PF00168.30 EGG02680.1 - 5.9e-25 87.5 0.0 2.6e-15 56.6 0.0 2.6 2 0 0 2 2 2 2 C2 domain MMM1 PF10296.9 EGG02680.1 - 0.093 11.8 0.6 0.51 9.3 0.0 2.3 3 0 0 3 3 3 0 Maintenance of mitochondrial morphology protein 1 Ferric_reduct PF01794.19 EGG02682.1 - 1.4e-21 76.9 9.1 1.4e-21 76.9 9.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGG02682.1 - 2.3e-14 53.8 0.0 1.7e-13 51.0 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGG02682.1 - 4.4e-12 46.1 0.0 9e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain zf-C2H2_jaz PF12171.8 EGG02684.1 - 0.054 13.8 3.2 0.12 12.7 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RNA_pol_Rpc4 PF05132.14 EGG02684.1 - 0.1 13.0 7.9 0.18 12.3 7.9 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 EGG02684.1 - 0.55 10.4 9.8 1.1 9.5 9.8 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 EGG02684.1 - 2.3 7.3 6.1 3.9 6.6 6.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 EGG02684.1 - 2.5 6.8 13.3 1.5 7.5 11.0 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 EGG02684.1 - 4.3 7.0 11.3 8.4 6.1 11.3 1.4 1 0 0 1 1 1 0 Connexin SpoIIP PF07454.11 EGG02684.1 - 8.4 5.8 15.5 4.1 6.8 11.5 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Pkinase PF00069.25 EGG02686.1 - 2.5e-58 197.5 0.0 2.9e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG02686.1 - 3.3e-30 105.2 0.0 4.8e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG02686.1 - 7.6e-06 24.9 0.0 1.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGG02686.1 - 0.0027 17.1 0.0 0.014 14.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG02686.1 - 0.032 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG02686.1 - 0.039 13.9 0.0 0.11 12.3 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGG02686.1 - 0.049 12.7 0.1 0.075 12.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EGG02686.1 - 0.051 12.5 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 EGG02687.1 - 2.1e-60 204.4 2.9 9.5e-39 133.3 0.6 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG02687.1 - 1e-26 93.8 0.5 3.4e-18 65.9 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGG02687.1 - 1.1e-05 24.9 0.2 0.00065 19.1 0.0 2.8 2 1 0 3 3 3 1 Kinase-like APH PF01636.23 EGG02687.1 - 7.2e-05 22.8 2.4 0.00028 20.9 1.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG02687.1 - 0.00031 19.8 0.2 0.00052 19.1 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGG02687.1 - 0.0054 16.1 0.1 0.034 13.5 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 EGG02687.1 - 0.012 16.3 0.3 0.041 14.6 0.0 2.1 2 0 0 2 2 2 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.11 EGG02687.1 - 0.03 13.3 0.1 0.046 12.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Med25_SD1 PF11235.8 EGG02687.1 - 0.13 12.6 0.1 0.25 11.7 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 RRM_1 PF00076.22 EGG02691.1 - 1.4e-13 50.4 0.0 2.5e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PH PF00169.29 EGG02692.1 - 1e-05 26.0 0.2 2.2e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 PH domain DUF2753 PF10952.8 EGG02692.1 - 0.076 13.1 0.3 0.14 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) DUF148 PF02520.17 EGG02692.1 - 0.17 12.0 4.0 0.82 9.8 2.8 2.5 2 1 1 3 3 3 0 Domain of unknown function DUF148 zf-C2H2 PF00096.26 EGG02693.1 - 1e-11 44.6 8.1 3.2e-06 27.3 0.8 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG02693.1 - 2e-06 28.0 10.6 6.3e-06 26.4 1.2 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG02693.1 - 8.8e-06 26.1 6.9 0.0051 17.5 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGG02693.1 - 5.5e-05 22.8 3.7 0.0079 15.9 0.3 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 EGG02693.1 - 0.0063 16.8 1.4 1.7 9.0 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 EGG02693.1 - 0.0064 16.4 3.1 0.16 11.9 0.3 2.2 2 1 0 2 2 2 1 SprT-like zinc ribbon domain zf-met PF12874.7 EGG02693.1 - 0.035 14.5 2.8 0.85 10.1 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 EGG02693.1 - 0.043 14.3 4.0 0.12 12.8 4.0 1.8 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_Tnp_IS1595 PF12760.7 EGG02693.1 - 0.12 12.3 3.2 4 7.5 0.2 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 EGG02693.1 - 0.17 12.0 3.5 12 6.1 3.9 2.0 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 EGG02693.1 - 1.4 9.0 7.4 1.5 8.9 1.5 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger Zn_clus PF00172.18 EGG02695.1 - 4.7e-05 23.4 2.8 6.6e-05 22.9 2.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EGG02696.1 - 7e-45 153.7 8.0 9.6e-45 153.3 8.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG02696.1 - 1.7e-23 83.1 7.5 1.7e-23 83.1 7.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily CN_hydrolase PF00795.22 EGG02697.1 - 1.3e-53 182.0 0.0 1.5e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SWIM PF04434.17 EGG02698.1 - 0.11 12.2 0.4 0.19 11.4 0.4 1.3 1 0 0 1 1 1 0 SWIM zinc finger Creatinase_N_2 PF16189.5 EGG02699.1 - 4.6e-40 137.4 0.0 2.5e-39 135.0 0.0 2.2 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EGG02699.1 - 8.4e-33 113.8 0.0 1.1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EGG02699.1 - 3.2e-18 66.7 0.0 1.1e-14 55.2 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EGG02699.1 - 6.9e-14 51.7 0.9 1.8e-13 50.3 0.9 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 PRC2_HTH_1 PF18118.1 EGG02701.1 - 0.39 11.5 0.1 0.39 11.5 0.1 2.1 2 1 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain RNA_pol_A_bac PF01000.26 EGG02702.1 - 5.2e-27 94.4 0.0 9.5e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGG02702.1 - 2.8e-16 58.7 0.0 3.9e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TYW3 PF02676.14 EGG02704.1 - 1.6e-47 161.6 0.0 2e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 ATP-synt_D PF01813.17 EGG02705.1 - 2.3e-71 239.7 4.3 2.7e-71 239.4 4.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Uds1 PF15456.6 EGG02705.1 - 0.033 14.4 0.2 0.033 14.4 0.2 2.1 2 1 0 2 2 2 0 Up-regulated During Septation DUF948 PF06103.11 EGG02705.1 - 0.57 10.5 4.1 0.97 9.7 0.3 2.7 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mem_trans PF03547.18 EGG02708.1 - 1.2e-31 109.5 5.7 2.8e-30 105.0 5.7 2.6 1 1 0 1 1 1 1 Membrane transport protein DUF3923 PF13061.6 EGG02708.1 - 0.064 13.4 2.6 2.6 8.2 2.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) Viral_Beta_CD PF04530.12 EGG02708.1 - 0.13 12.6 0.2 6.4 7.1 0.3 2.9 3 0 0 3 3 3 0 Viral Beta C/D like family Claudin_2 PF13903.6 EGG02708.1 - 0.2 11.4 2.8 0.38 10.5 1.1 2.3 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction CAP59_mtransfer PF11735.8 EGG02710.1 - 3.2e-69 233.3 0.0 5.2e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 HSP70 PF00012.20 EGG02711.1 - 7.7e-260 863.2 14.0 9.4e-260 862.9 14.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGG02711.1 - 4.2e-12 45.5 3.6 8.6e-10 37.9 2.3 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EGG02711.1 - 0.0068 16.8 6.0 3.8 8.0 0.0 4.1 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 EGG02711.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Stress-antifung PF01657.17 EGG02720.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 Salt stress response/antifungal Aminotran_5 PF00266.19 EGG02721.1 - 1.9e-25 89.6 0.0 2.5e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGG02721.1 - 3.5e-08 33.0 0.0 6.9e-08 32.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II AAA_5 PF07728.14 EGG02722.1 - 4.5e-103 340.9 0.0 2.2e-23 82.8 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EGG02722.1 - 8.4e-46 154.5 16.2 6.6e-19 68.1 0.6 7.2 8 0 0 8 8 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 EGG02722.1 - 9.9e-29 99.5 1.8 1.2e-26 92.8 0.2 4.5 4 0 0 4 4 3 1 Midasin AAA lid domain AAA PF00004.29 EGG02722.1 - 4.7e-25 88.5 0.0 0.00026 21.4 0.0 8.2 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG02722.1 - 3e-24 86.3 5.9 0.0067 16.8 0.1 7.7 6 1 0 6 6 6 5 AAA ATPase domain AAA_3 PF07726.11 EGG02722.1 - 1.5e-23 83.1 0.0 6.7e-10 38.9 0.0 6.4 7 0 0 7 7 5 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGG02722.1 - 1.3e-22 80.2 0.1 0.00018 21.1 0.0 5.9 5 0 0 5 5 5 4 P-loop containing dynein motor region AAA_18 PF13238.6 EGG02722.1 - 2.1e-19 70.3 0.1 0.019 15.5 0.0 7.5 6 0 0 6 6 6 3 AAA domain Dynein_heavy PF03028.15 EGG02722.1 - 3.2e-17 62.7 0.0 0.015 15.3 0.0 7.4 6 0 0 6 6 6 4 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 EGG02722.1 - 1.1e-16 61.3 0.0 0.09 13.0 0.0 7.2 6 0 0 6 6 6 4 AAA domain AAA_6 PF12774.7 EGG02722.1 - 1.7e-15 56.8 0.0 0.42 9.5 0.0 7.8 8 1 0 8 8 7 5 Hydrolytic ATP binding site of dynein motor region Sigma54_activat PF00158.26 EGG02722.1 - 7.1e-14 51.9 0.0 0.18 11.5 0.0 5.5 5 0 0 5 5 5 4 Sigma-54 interaction domain AAA_14 PF13173.6 EGG02722.1 - 2e-12 47.2 0.0 0.024 14.7 0.0 7.7 7 1 0 7 7 7 2 AAA domain T2SSE PF00437.20 EGG02722.1 - 3.2e-12 46.1 1.7 0.037 13.1 0.0 5.7 5 0 0 5 5 5 3 Type II/IV secretion system protein TsaE PF02367.17 EGG02722.1 - 7e-12 45.4 0.3 1.5 8.8 0.0 6.4 6 0 0 6 6 5 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 EGG02722.1 - 4.7e-10 39.7 1.8 0.019 15.1 0.0 5.9 7 0 0 7 7 5 2 Sigma-54 interaction domain AAA_30 PF13604.6 EGG02722.1 - 8.1e-10 38.7 0.0 1.1 9.0 0.0 6.8 5 1 0 5 5 5 2 AAA domain RNA_helicase PF00910.22 EGG02722.1 - 1.4e-09 38.3 0.0 9.4 6.7 0.0 7.0 6 0 0 6 6 6 0 RNA helicase AAA_33 PF13671.6 EGG02722.1 - 1.6e-09 38.1 0.0 1.9 8.7 0.0 6.5 6 0 0 6 6 6 1 AAA domain Zeta_toxin PF06414.12 EGG02722.1 - 2e-09 37.0 0.0 0.39 10.0 0.0 5.9 6 0 0 6 6 5 1 Zeta toxin RsgA_GTPase PF03193.16 EGG02722.1 - 2.7e-09 37.2 3.1 1.3 8.9 0.0 6.1 6 0 0 6 6 6 1 RsgA GTPase AAA_29 PF13555.6 EGG02722.1 - 5.2e-09 35.7 2.3 5 6.9 0.0 6.9 7 0 0 7 7 6 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EGG02722.1 - 5.7e-09 36.4 6.4 1.6 9.0 0.0 6.9 6 0 0 6 6 6 1 AAA domain DUF815 PF05673.13 EGG02722.1 - 1.2e-08 34.4 1.3 0.068 12.3 0.0 4.8 5 0 0 5 5 5 3 Protein of unknown function (DUF815) TniB PF05621.11 EGG02722.1 - 7.4e-08 32.0 0.1 1.7 8.0 0.0 5.9 5 0 0 5 5 5 1 Bacterial TniB protein AAA_19 PF13245.6 EGG02722.1 - 1.6e-07 31.8 3.6 1.2 9.4 0.0 6.7 7 0 0 7 7 5 1 AAA domain Roc PF08477.13 EGG02722.1 - 8.9e-07 29.2 2.2 4.8 7.4 0.0 6.3 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EGG02722.1 - 1.4e-06 28.8 11.0 0.39 11.2 0.2 7.0 7 0 0 7 7 6 2 ABC transporter RuvB_N PF05496.12 EGG02722.1 - 1.8e-06 27.8 0.2 2.1 8.0 0.0 6.7 8 0 0 8 8 7 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EGG02722.1 - 2.1e-06 27.3 3.7 18 4.6 0.0 8.2 8 2 2 10 10 9 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGG02722.1 - 3.5e-06 26.9 0.0 3.5 7.3 0.0 4.7 5 0 0 5 5 4 0 IstB-like ATP binding protein VWA_2 PF13519.6 EGG02722.1 - 1.1e-05 26.0 0.1 9.1e-05 23.1 0.1 2.7 1 0 0 1 1 1 1 von Willebrand factor type A domain ATPase_2 PF01637.18 EGG02722.1 - 2e-05 24.7 0.0 2.9 7.7 0.0 5.1 5 0 0 5 5 5 1 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 EGG02722.1 - 2.6e-05 24.2 0.1 0.11 12.2 0.0 4.5 4 0 0 4 4 4 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EGG02722.1 - 3.2e-05 23.8 0.0 44 3.7 0.0 6.1 7 0 0 7 7 6 0 AAA domain MMR_HSR1 PF01926.23 EGG02722.1 - 4.2e-05 23.6 4.9 8.9 6.4 0.0 6.3 6 0 0 6 6 6 0 50S ribosome-binding GTPase NACHT PF05729.12 EGG02722.1 - 6.8e-05 22.8 0.3 15 5.4 0.0 5.6 5 0 0 5 5 5 0 NACHT domain Rad17 PF03215.15 EGG02722.1 - 0.00011 22.1 0.1 18 5.2 0.0 5.2 5 0 0 5 5 5 0 Rad17 P-loop domain KTI12 PF08433.10 EGG02722.1 - 0.00012 21.6 0.2 2.8 7.3 0.0 5.8 6 0 0 6 6 6 1 Chromatin associated protein KTI12 AAA_25 PF13481.6 EGG02722.1 - 0.00021 20.9 1.7 24 4.5 0.1 6.1 7 0 0 7 7 6 0 AAA domain CPT PF07931.12 EGG02722.1 - 0.00025 21.0 5.7 2.3 8.0 0.0 6.6 7 1 0 7 7 6 1 Chloramphenicol phosphotransferase-like protein PhoH PF02562.16 EGG02722.1 - 0.00036 20.0 0.0 1.2 8.5 0.0 3.2 3 0 0 3 3 3 2 PhoH-like protein VWA PF00092.28 EGG02722.1 - 0.0007 19.9 1.2 0.002 18.4 0.1 2.4 2 0 0 2 2 1 1 von Willebrand factor type A domain PduV-EutP PF10662.9 EGG02722.1 - 0.00082 19.1 0.4 14 5.4 0.0 5.1 6 0 0 6 6 5 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 EGG02722.1 - 0.0016 18.4 1.6 4.8 7.1 0.0 5.1 6 0 0 6 6 5 0 NTPase TIP49 PF06068.13 EGG02722.1 - 0.0018 17.5 0.4 7.7 5.6 0.1 4.2 5 0 0 5 5 5 0 TIP49 P-loop domain SRPRB PF09439.10 EGG02722.1 - 0.0027 17.2 2.7 23 4.4 0.1 5.5 7 0 0 7 7 6 0 Signal recognition particle receptor beta subunit IPT PF01745.16 EGG02722.1 - 0.0071 15.8 0.5 3 7.2 0.0 3.5 4 0 0 4 4 3 1 Isopentenyl transferase SRP54 PF00448.22 EGG02722.1 - 0.018 14.7 0.1 9.3 5.8 0.0 3.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Cytidylate_kin PF02224.18 EGG02722.1 - 0.026 14.3 0.5 9.8 5.8 0.0 4.0 4 0 0 4 4 3 0 Cytidylate kinase ResIII PF04851.15 EGG02722.1 - 0.027 14.5 0.0 2.6 8.0 0.0 4.3 5 0 0 5 5 2 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 EGG02722.1 - 0.064 12.4 0.1 24 4.0 0.0 4.0 4 0 0 4 4 4 0 NB-ARC domain dNK PF01712.19 EGG02722.1 - 0.093 12.6 2.1 14 5.4 0.0 4.4 4 0 0 4 4 3 0 Deoxynucleoside kinase AAA_23 PF13476.6 EGG02722.1 - 0.13 12.8 27.9 1.3 9.5 0.2 7.9 9 0 0 9 9 5 0 AAA domain AAA_11 PF13086.6 EGG02722.1 - 0.14 11.9 0.0 0.14 11.9 0.0 7.0 8 0 0 8 8 5 0 AAA domain Gtr1_RagA PF04670.12 EGG02722.1 - 0.2 11.0 1.6 52 3.1 0.1 4.8 6 0 0 6 6 6 0 Gtr1/RagA G protein conserved region cobW PF02492.19 EGG02722.1 - 0.51 9.9 5.8 47 3.5 0.0 5.1 6 0 0 6 6 4 0 CobW/HypB/UreG, nucleotide-binding domain UQ_con PF00179.26 EGG02723.1 - 2e-49 166.8 0.0 2.3e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGG02723.1 - 0.0023 17.6 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGG02723.1 - 0.18 12.1 0.0 0.23 11.8 0.0 1.3 1 1 0 1 1 1 0 RWD domain Pilin_N PF07790.11 EGG02724.1 - 0.21 12.5 2.7 0.94 10.5 0.3 2.4 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal TFIIA_gamma_C PF02751.14 EGG02726.1 - 7.1e-09 35.7 1.0 0.00041 20.4 0.0 2.2 1 1 1 2 2 2 2 Transcription initiation factor IIA, gamma subunit zf-dskA_traR PF01258.17 EGG02726.1 - 0.035 14.1 2.9 0.17 11.9 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-CCHC PF00098.23 EGG02726.1 - 0.17 12.0 1.7 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 Zinc knuckle LRR_4 PF12799.7 EGG02727.1 - 0.57 10.7 2.9 4.7 7.8 0.1 3.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGG02727.1 - 4 8.4 0.0 4 8.4 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat F-box-like PF12937.7 EGG02728.1 - 0.0038 17.1 0.1 0.015 15.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like Rep_4 PF05797.11 EGG02728.1 - 0.1 11.7 0.4 0.16 11.1 0.4 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) DPBB_1 PF03330.18 EGG02732.1 - 4.6e-09 36.4 0.0 7.7e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EGG02732.1 - 0.00052 19.9 0.1 0.00072 19.4 0.1 1.3 1 1 0 1 1 1 1 Barwin family NDUFA12 PF05071.16 EGG02733.1 - 4.4e-29 101.2 2.0 5.1e-29 101.0 2.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Ferric_reduct PF01794.19 EGG02734.1 - 5e-19 68.7 12.7 9.9e-19 67.7 7.8 2.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGG02734.1 - 1.3e-12 47.8 0.1 3.7e-12 46.3 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 EGG02734.1 - 3.5e-07 30.5 0.0 0.00016 21.8 0.1 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ni_hydr_CYTB PF01292.20 EGG02734.1 - 0.02 14.5 0.5 0.02 14.5 0.5 1.9 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 CBP_BcsR PF10945.8 EGG02735.1 - 0.2 11.1 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR Nop14 PF04147.12 EGG02742.1 - 0.049 11.9 3.2 0.058 11.6 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family FXMRP1_C_core PF12235.8 EGG02742.1 - 0.86 10.2 28.5 0.051 14.2 10.7 2.6 2 1 0 2 2 2 0 Fragile X-related 1 protein core C terminal PHC2_SAM_assoc PF16616.5 EGG02742.1 - 2.3 9.0 5.4 4.9 8.0 2.0 2.6 3 0 0 3 3 3 0 Unstructured region on Polyhomeotic-like protein 1 and 2 DUF948 PF06103.11 EGG02746.1 - 0.00051 20.3 1.3 0.00074 19.7 0.3 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Methyltransf_11 PF08241.12 EGG02750.1 - 1.4e-10 41.7 0.0 2.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG02750.1 - 2.2e-08 34.7 0.0 3.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG02750.1 - 4.4e-08 33.1 0.0 6.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG02750.1 - 1.4e-06 29.0 0.0 2.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG02750.1 - 0.00072 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG02750.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EGG02750.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EGG02750.1 - 0.032 14.0 0.0 0.087 12.6 0.0 1.7 1 1 1 2 2 2 0 Lysine methyltransferase CRISPR_Cse2 PF09485.10 EGG02750.1 - 0.067 13.7 0.0 0.14 12.7 0.0 1.4 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DLIC PF05783.11 EGG02751.1 - 1.3e-53 182.5 10.1 2.8e-36 125.4 0.0 5.0 4 1 0 5 5 5 4 Dynein light intermediate chain (DLIC) Arf PF00025.21 EGG02751.1 - 0.24 10.8 0.1 0.61 9.5 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Peptidase_S8 PF00082.22 EGG02753.1 - 2.8e-31 108.9 0.0 6.5e-31 107.7 0.0 1.6 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EGG02753.1 - 5.8e-14 52.8 1.2 8.9e-14 52.2 0.1 1.9 2 0 0 2 2 2 1 Fn3-like domain PA PF02225.22 EGG02753.1 - 0.0003 20.8 0.0 0.003 17.6 0.0 2.4 2 0 0 2 2 2 1 PA domain Tau95_N PF17682.1 EGG02754.1 - 0.13 12.4 4.2 0.17 12.1 4.2 1.1 1 0 0 1 1 1 0 Tau95 Triple barrel domain ANAPC15 PF15243.6 EGG02754.1 - 0.55 10.7 7.9 0.84 10.1 7.9 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 V_ATPase_I PF01496.19 EGG02754.1 - 1.5 6.7 6.7 1.7 6.5 6.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DAP PF15228.6 EGG02754.1 - 1.7 9.8 8.2 0.81 10.9 4.5 1.9 2 0 0 2 2 2 0 Death-associated protein Presenilin PF01080.17 EGG02754.1 - 2 7.1 7.8 2.1 7.0 7.8 1.0 1 0 0 1 1 1 0 Presenilin DUF3959 PF13105.6 EGG02754.1 - 6.3 6.2 5.9 3.9 6.9 4.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) PI3_PI4_kinase PF00454.27 EGG02755.1 - 6e-53 180.2 0.0 1.7e-52 178.8 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 EGG02755.1 - 1.8e-23 82.4 0.0 1.5e-22 79.4 0.0 2.8 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.23 EGG02755.1 - 5.1e-12 45.7 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 EGG02755.1 - 0.004 17.1 0.0 0.035 14.0 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) COX15-CtaA PF02628.15 EGG02756.1 - 9.1e-102 340.4 2.5 1.1e-101 340.1 2.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF1929 PF09118.11 EGG02756.1 - 0.092 13.0 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) tRNA_m1G_MT PF01746.21 EGG02758.1 - 6.2e-29 101.1 0.7 2.2e-27 96.1 0.7 2.1 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Sugar_tr PF00083.24 EGG02759.1 - 1.6e-124 416.2 22.1 1.9e-124 416.0 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG02759.1 - 2.6e-26 92.4 57.0 2.7e-22 79.2 29.7 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Btz PF09405.10 EGG02760.1 - 0.0049 17.1 15.5 0.0049 17.1 15.5 4.0 3 1 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding PBP1_TM PF14812.6 EGG02760.1 - 0.091 13.1 3.2 0.36 11.2 3.2 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S24 PF00717.23 EGG02762.1 - 8.9e-08 32.0 0.2 3.5e-07 30.1 0.2 1.9 1 1 0 1 1 1 1 Peptidase S24-like CSD2 PF17876.1 EGG02762.1 - 0.011 15.9 0.1 0.016 15.4 0.1 1.3 1 0 0 1 1 1 0 Cold shock domain DUF4889 PF16230.5 EGG02762.1 - 0.078 13.2 0.2 0.2 11.9 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4889) TIP41 PF04176.13 EGG02764.1 - 2.7e-65 219.0 0.0 3.4e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Glyco_hydro_18 PF00704.28 EGG02766.1 - 2.1e-56 192.0 0.0 2.5e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 EGG02766.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 DUF2058 PF09831.9 EGG02770.1 - 0.045 13.9 0.6 0.045 13.9 0.6 3.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2058) SET PF00856.28 EGG02771.1 - 0.021 15.2 0.9 0.021 15.2 0.9 2.4 2 1 0 2 2 2 0 SET domain TIP120 PF08623.10 EGG02771.1 - 0.31 10.8 5.1 7.5 6.3 0.2 3.3 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) Telomerase_RBD PF12009.8 EGG02772.1 - 2.4e-13 50.4 1.0 5.1e-13 49.3 1.0 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain HAS-barrel PF09378.10 EGG02772.1 - 0.088 13.0 0.0 0.55 10.4 0.0 2.0 1 1 1 2 2 2 0 HAS barrel domain DUF2564 PF10819.8 EGG02773.1 - 0.062 13.7 0.7 0.16 12.4 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) CxC5 PF18718.1 EGG02774.1 - 9.6e-24 83.7 7.6 2e-23 82.7 7.6 1.6 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG02774.1 - 7.5e-19 67.8 1.1 7.5e-19 67.8 1.1 2.1 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases FAD_binding_3 PF01494.19 EGG02775.1 - 1.1e-80 271.5 0.0 6.5e-80 269.0 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGG02775.1 - 6.4e-44 149.9 0.0 1.3e-43 148.9 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_3 PF13738.6 EGG02775.1 - 0.00011 21.6 0.2 0.00017 21.0 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGG02775.1 - 0.00024 19.9 0.1 0.00042 19.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EGG02775.1 - 0.00036 19.8 0.1 0.00052 19.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGG02775.1 - 0.00045 20.4 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 EGG02775.1 - 0.0027 17.1 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family Pyr_redox_2 PF07992.14 EGG02775.1 - 0.0027 17.0 0.1 0.0047 16.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGG02775.1 - 0.0029 16.9 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 EGG02775.1 - 0.0085 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EGG02775.1 - 0.0088 14.9 0.1 0.013 14.4 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 EGG02775.1 - 0.013 15.1 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGG02775.1 - 0.026 13.6 0.1 0.078 12.0 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EGG02775.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EGG02775.1 - 0.13 12.8 0.1 0.3 11.7 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EGG02775.1 - 0.16 12.1 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SE PF08491.10 EGG02775.1 - 0.19 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase GH131_N PF18271.1 EGG02776.1 - 9.1e-28 97.6 0.1 1e-27 97.5 0.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain GH131_N PF18271.1 EGG02777.1 - 3e-10 40.2 0.0 3.5e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain GH131_N PF18271.1 EGG02778.1 - 3e-31 109.1 0.0 3.5e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain PAP_central PF04928.17 EGG02779.1 - 2.3e-108 360.9 0.0 3.2e-108 360.4 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EGG02779.1 - 6.6e-42 143.0 0.0 1e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EGG02779.1 - 8.8e-12 45.2 0.0 2.1e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EGG02779.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Abhydrolase_2 PF02230.16 EGG02780.1 - 2.7e-27 96.0 0.0 7.5e-27 94.5 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGG02780.1 - 5.3e-05 23.9 0.2 0.00014 22.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGG02780.1 - 0.06 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Luteo_Vpg PF01659.16 EGG02780.1 - 0.38 11.1 2.3 2.4 8.5 0.0 2.9 2 1 0 2 2 2 0 Luteovirus putative VPg genome linked protein Sushi PF00084.20 EGG02781.1 - 0.014 16.0 0.3 0.014 16.0 0.3 2.4 3 0 0 3 3 3 0 Sushi repeat (SCR repeat) DUF5572 PF17733.1 EGG02782.1 - 2.1e-09 37.0 0.1 4.8e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5572) BetaGal_dom3 PF13363.6 EGG02782.1 - 0.19 11.3 1.2 0.29 10.7 0.3 1.7 1 1 1 2 2 2 0 Beta-galactosidase, domain 3 DUF4097 PF13349.6 EGG02783.1 - 0.01 15.2 4.1 0.065 12.6 4.1 2.2 1 1 0 1 1 1 0 Putative adhesin Helitron_like_N PF14214.6 EGG02785.1 - 0.077 13.2 0.0 2.8 8.1 0.1 2.1 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus FRQ PF09421.10 EGG02786.1 - 0.15 10.0 3.8 0.17 9.9 3.8 1.1 1 0 0 1 1 1 0 Frequency clock protein NCE101 PF11654.8 EGG02788.1 - 0.11 12.3 0.0 0.57 9.9 0.0 2.3 2 0 0 2 2 2 0 Non-classical export protein 1 V_ATPase_I PF01496.19 EGG02788.1 - 0.4 8.5 3.1 0.63 7.9 3.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SR-25 PF10500.9 EGG02788.1 - 0.59 9.7 17.5 0.085 12.5 6.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4746 PF15928.5 EGG02788.1 - 0.85 9.0 15.0 1.7 8.0 15.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) VasI PF11319.8 EGG02788.1 - 1.7 8.3 3.7 0.65 9.6 0.0 2.0 2 0 0 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 NARP1 PF12569.8 EGG02788.1 - 3.3 6.5 11.8 5.5 5.8 11.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.10 EGG02788.1 - 3.8 7.8 15.4 13 6.1 15.4 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 WD40 PF00400.32 EGG02789.1 - 4.1e-47 157.2 15.8 1.7e-07 31.8 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG02789.1 - 3.5e-09 36.8 0.6 0.1 12.9 0.0 3.8 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG02789.1 - 6.3e-09 35.0 5.7 0.31 9.6 0.1 5.1 2 1 2 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 EGG02789.1 - 1.1e-08 34.8 1.6 0.056 12.8 0.0 4.0 3 1 1 4 4 4 4 WD40-like domain SANT_DAMP1_like PF16282.5 EGG02790.1 - 9.7e-31 105.8 3.7 2.9e-30 104.3 3.7 1.9 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 MecA PF05389.12 EGG02790.1 - 0.037 13.7 8.7 0.062 12.9 0.1 2.5 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Myb_DNA-binding PF00249.31 EGG02790.1 - 0.048 13.9 0.0 0.3 11.3 0.0 2.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG02790.1 - 0.049 13.9 1.8 0.94 9.8 0.0 3.4 3 1 1 4 4 4 0 Myb-like DNA-binding domain YqfQ PF14181.6 EGG02790.1 - 0.054 13.7 2.0 0.19 11.9 2.0 1.9 1 0 0 1 1 1 0 YqfQ-like protein Viral_P18 PF04521.13 EGG02790.1 - 0.056 13.2 0.2 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Uds1 PF15456.6 EGG02790.1 - 0.2 11.8 8.4 0.73 10.0 0.1 2.6 2 0 0 2 2 2 0 Up-regulated During Septation HTH_3 PF01381.22 EGG02793.1 - 0.023 14.7 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix Phage_int_SAM_1 PF02899.17 EGG02793.1 - 0.074 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Indigoidine_A PF04227.12 EGG02794.1 - 8.1e-118 393.0 0.7 9.2e-118 392.8 0.7 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein MerR_2 PF13591.6 EGG02794.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 MerR HTH family regulatory protein ETC_C1_NDUFA5 PF04716.14 EGG02796.1 - 4.1e-21 74.6 0.4 9e-21 73.5 0.4 1.6 1 0 0 1 1 1 1 ETC complex I subunit conserved region LemA PF04011.12 EGG02799.1 - 0.014 15.3 2.4 0.055 13.3 0.3 2.5 2 0 0 2 2 2 0 LemA family AAA_23 PF13476.6 EGG02800.1 - 8.9e-19 68.8 1.9 1e-18 68.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EGG02800.1 - 2.6e-13 49.9 1.1 3.5e-13 49.5 0.2 1.5 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGG02800.1 - 5.8e-06 26.3 0.0 2.2e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGG02800.1 - 7.6e-06 25.9 0.1 2e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGG02800.1 - 0.00061 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 EGG02800.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGG02800.1 - 0.081 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein SMC_N PF02463.19 EGG02801.1 - 1.4e-06 27.9 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Helicase_C_2 PF13307.6 EGG02802.1 - 3.1e-53 180.5 0.0 7.2e-53 179.3 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EGG02802.1 - 2.1e-44 151.2 0.3 8.7e-44 149.2 0.3 2.1 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EGG02802.1 - 0.00012 22.2 0.1 0.79 9.7 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG02802.1 - 0.023 14.5 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.16 EGG02802.1 - 0.023 14.1 0.0 6.5 6.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 EGG02802.1 - 0.063 13.6 0.0 2.4 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain RepL PF05732.11 EGG02802.1 - 0.066 12.7 0.9 0.14 11.6 0.9 1.5 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) UPRTase PF14681.6 EGG02804.1 - 0.077 12.4 0.5 0.16 11.4 0.1 1.7 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase NUFIP1 PF10453.9 EGG02807.1 - 1.8e-11 43.7 1.8 3e-11 43.0 0.2 2.2 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 EGG02807.1 - 2.8e-05 23.9 0.3 5.3e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF5320 PF17253.2 EGG02807.1 - 0.016 16.3 3.7 0.081 14.0 2.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) zf_CCCH_4 PF18345.1 EGG02807.1 - 0.02 14.9 3.3 0.037 14.1 3.3 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 EGG02807.1 - 0.025 15.0 1.5 0.025 15.0 1.5 1.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EGG02807.1 - 0.079 12.8 1.4 0.15 11.9 1.4 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger C1_4 PF07975.12 EGG02807.1 - 0.61 10.4 3.5 1.5 9.1 3.5 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain Cyt-b5 PF00173.28 EGG02808.1 - 2.5e-21 75.6 0.0 2.8e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Plasmo_rep PF12135.8 EGG02808.1 - 0.14 11.7 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Plasmodium repeat family GTP_EFTU PF00009.27 EGG02812.1 - 2.7e-34 118.4 3.0 9.6e-33 113.4 3.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGG02812.1 - 2.7e-26 91.7 0.6 1.3e-25 89.6 0.1 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EGG02812.1 - 6.8e-08 32.6 0.1 1.8e-07 31.2 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGG02812.1 - 6.1e-06 26.0 2.0 9.2e-05 22.2 0.7 2.8 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 EGG02812.1 - 5.7e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 EGG02812.1 - 9e-05 22.4 0.7 0.23 11.4 0.1 2.6 1 1 1 2 2 2 2 RsgA GTPase Roc PF08477.13 EGG02812.1 - 0.0008 19.6 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGG02812.1 - 0.0037 16.7 3.1 0.0047 16.4 0.2 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 EGG02812.1 - 0.015 15.7 3.6 0.045 14.1 0.4 3.2 3 0 0 3 3 3 0 Elongation factor Tu domain 2 FeoB_N PF02421.18 EGG02812.1 - 0.058 12.9 0.1 0.17 11.4 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MnmE_helical PF12631.7 EGG02812.1 - 0.073 13.2 0.4 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 MnmE helical domain AAA_23 PF13476.6 EGG02812.1 - 0.24 11.9 0.0 0.24 11.9 0.0 3.0 3 2 0 3 3 2 0 AAA domain Retrotran_gag_2 PF14223.6 EGG02818.1 - 4.6e-13 49.0 0.1 9.3e-13 48.0 0.1 1.5 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type PalH PF08733.10 EGG02819.1 - 5.5 5.9 20.5 9.1 5.2 20.2 1.4 1 1 0 1 1 1 0 PalH/RIM21 DUF4834 PF16118.5 EGG02820.1 - 0.059 14.3 1.9 0.081 13.9 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DapH_N PF08503.10 EGG02821.1 - 0.0023 18.1 2.7 0.005 17.0 2.7 1.6 1 1 0 1 1 1 1 Tetrahydrodipicolinate succinyltransferase N-terminal LSDAT_prok PF18171.1 EGG02821.1 - 0.046 12.9 1.5 0.056 12.7 1.5 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Yippee-Mis18 PF03226.14 EGG02823.1 - 1.6e-15 57.2 0.1 1.9e-15 56.9 0.1 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EGG02823.1 - 0.013 15.7 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 C-terminal domain of RIG-I RNA_pol_N PF01194.17 EGG02823.1 - 0.054 13.8 1.7 0.42 11.0 0.1 2.1 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit zinc_ribbon_2 PF13240.6 EGG02823.1 - 0.11 12.3 0.6 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Mpp10 PF04006.12 EGG02824.1 - 5.6e-71 239.8 11.3 6.2e-71 239.7 11.3 1.0 1 0 0 1 1 1 1 Mpp10 protein Prp18 PF02840.15 EGG02825.1 - 2.1e-61 206.2 2.2 3.5e-61 205.4 0.1 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EGG02825.1 - 4.2e-11 42.2 6.7 8.5e-11 41.2 6.7 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like GFO_IDH_MocA PF01408.22 EGG02826.1 - 6.2e-21 75.4 0.1 1.1e-20 74.6 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DUF521 PF04412.13 EGG02826.1 - 0.039 12.7 0.0 0.053 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Corona_NS2A PF05213.12 EGG02826.1 - 0.066 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Coronavirus NS2A protein Adaptin_N PF01602.20 EGG02827.1 - 8.8e-115 384.2 0.2 1.2e-114 383.7 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EGG02827.1 - 3.6e-53 179.7 0.0 7.1e-53 178.8 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EGG02827.1 - 8.7e-32 109.7 0.0 2.6e-31 108.1 0.0 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EGG02827.1 - 1.6e-17 63.6 0.4 2.4e-09 37.5 0.0 4.8 3 1 3 6 6 6 3 HEAT repeats Cnd1 PF12717.7 EGG02827.1 - 3.9e-06 27.0 7.6 0.13 12.3 0.1 4.8 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGG02827.1 - 0.0038 17.4 4.5 4.2 7.9 0.1 5.0 5 0 0 5 5 5 1 HEAT repeat DUF3385 PF11865.8 EGG02827.1 - 0.053 13.4 1.1 14 5.6 0.0 3.7 2 1 0 3 3 3 0 Domain of unknown function (DUF3385) Alpha_kinase PF02816.18 EGG02828.1 - 0.01 16.0 0.1 0.015 15.4 0.1 1.2 1 0 0 1 1 1 0 Alpha-kinase family DUF4420 PF14390.6 EGG02830.1 - 0.036 13.3 0.2 0.048 12.9 0.2 1.2 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) HABP4_PAI-RBP1 PF04774.15 EGG02832.1 - 0.0037 18.1 10.3 0.0037 18.1 10.3 2.8 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 EGG02832.1 - 0.014 16.2 0.9 0.014 16.2 0.9 4.0 4 2 0 4 4 4 0 Stm1 Baculo_11_kDa PF06143.11 EGG02833.1 - 1.8 8.2 6.9 0.18 11.4 0.6 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family CDK2AP PF09806.9 EGG02834.1 - 0.0024 18.0 2.2 0.0027 17.8 2.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein ProSAAS PF07259.12 EGG02834.1 - 0.077 13.0 1.7 0.11 12.5 1.7 1.2 1 0 0 1 1 1 0 ProSAAS precursor VIR_N PF15912.5 EGG02834.1 - 1.1 8.8 5.7 1.3 8.6 5.7 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal DUF1682 PF07946.14 EGG02834.1 - 1.8 7.7 8.0 2.4 7.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SRP-alpha_N PF04086.13 EGG02834.1 - 3.4 7.5 15.9 4.4 7.1 15.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 EGG02834.1 - 8.4 5.0 8.3 8.8 5.0 8.3 1.1 1 0 0 1 1 1 0 Presenilin CmcI PF04989.12 EGG02837.1 - 0.044 13.5 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase Mago-bind PF09282.10 EGG02838.1 - 0.013 15.3 10.5 1.1 9.2 0.2 3.3 3 0 0 3 3 3 0 Mago binding SspK PF08176.12 EGG02838.1 - 0.43 10.9 6.5 14 6.0 0.2 3.2 3 0 0 3 3 3 0 Small acid-soluble spore protein K family Diedel PF13164.6 EGG02839.1 - 0.0086 16.5 3.7 0.0091 16.4 3.7 1.2 1 0 0 1 1 1 1 Diedel Vitelline_membr PF10542.9 EGG02841.1 - 0.028 14.3 0.3 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region FAD_binding_3 PF01494.19 EGG02844.1 - 1.8e-83 280.7 0.0 9.2e-61 206.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.12 EGG02844.1 - 4.6e-45 153.6 0.0 1.8e-44 151.7 0.0 2.0 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_3 PF13738.6 EGG02844.1 - 9.1e-05 21.9 0.2 0.00016 21.1 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG02844.1 - 0.00019 21.6 0.1 0.00041 20.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGG02844.1 - 0.00019 20.6 0.1 0.00028 20.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGG02844.1 - 0.00031 19.6 0.1 0.00056 18.7 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EGG02844.1 - 0.0021 17.7 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGG02844.1 - 0.0035 16.4 0.1 0.051 12.6 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 EGG02844.1 - 0.0044 16.3 0.2 0.0085 15.4 0.2 1.5 1 1 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 EGG02844.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EGG02844.1 - 0.014 14.3 0.1 0.022 13.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase ThiF PF00899.21 EGG02844.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 ThiF family Pyr_redox_2 PF07992.14 EGG02844.1 - 0.015 14.5 0.2 0.029 13.6 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 EGG02844.1 - 0.068 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus GIDA PF01134.22 EGG02844.1 - 0.091 11.8 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EGG02844.1 - 0.14 12.8 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SPO22 PF08631.10 EGG02845.1 - 2.6e-13 50.1 11.9 0.00055 19.5 0.2 4.1 4 0 0 4 4 4 3 Meiosis protein SPO22/ZIP4 like FokI_C PF02980.16 EGG02845.1 - 0.13 12.3 0.4 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Restriction endonuclease FokI, catalytic domain Abhydrolase_2 PF02230.16 EGG02846.1 - 2.7e-27 96.0 0.0 7.5e-27 94.5 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGG02846.1 - 4.4e-05 24.2 0.3 0.00014 22.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGG02846.1 - 0.06 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Luteo_Vpg PF01659.16 EGG02846.1 - 0.28 11.5 1.6 2.4 8.5 0.0 2.8 2 1 0 2 2 2 0 Luteovirus putative VPg genome linked protein UCH PF00443.29 EGG02847.1 - 3.7e-47 161.0 0.0 9.5e-47 159.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EGG02847.1 - 4.1e-23 81.1 0.4 1.7e-15 56.7 0.0 3.5 3 0 0 3 3 3 3 A repeated domain in UCH-protein UCH_1 PF13423.6 EGG02847.1 - 1.3e-10 41.4 1.2 3.9e-05 23.4 0.1 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase AKNA PF12443.8 EGG02847.1 - 0.099 13.3 0.1 0.63 10.7 0.1 2.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor Ca_chan_IQ PF08763.11 EGG02847.1 - 0.21 11.8 2.2 5.9 7.2 0.0 2.6 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain AKAP2_C PF15304.6 EGG02847.1 - 1.1 8.5 6.7 0.24 10.6 2.0 2.1 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus Linker_histone PF00538.19 EGG02849.1 - 4.1e-21 75.1 0.2 4.1e-21 75.1 0.2 2.6 2 1 0 2 2 2 1 linker histone H1 and H5 family UCH PF00443.29 EGG02850.1 - 5.1e-39 134.3 1.2 9.4e-39 133.4 1.2 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG02850.1 - 1.9e-06 27.7 12.6 4.1e-06 26.6 12.6 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Occludin_ELL PF07303.13 EGG02850.1 - 0.64 10.8 5.0 2 9.2 2.2 2.6 2 0 0 2 2 2 0 Occludin homology domain zf-C2H2_2 PF12756.7 EGG02850.1 - 2.5 8.5 8.5 0.45 10.9 3.0 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Nop53 PF07767.11 EGG02853.1 - 4.7e-43 148.1 22.7 5.9e-43 147.8 22.7 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Glyco_hydro_63 PF03200.16 EGG02853.1 - 0.021 13.6 1.3 0.037 12.8 1.3 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain DUF769 PF05590.11 EGG02853.1 - 0.14 11.6 2.7 0.43 10.0 0.0 2.4 2 1 0 2 2 2 0 Xylella fastidiosa protein of unknown function (DUF769) hDGE_amylase PF14701.6 EGG02853.1 - 2.4 7.1 10.5 0.21 10.6 5.7 1.6 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain V_ATPase_I PF01496.19 EGG02853.1 - 7.1 4.4 9.8 13 3.6 9.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SURF4 PF02077.15 EGG02855.1 - 1.6e-72 244.3 1.9 1.9e-72 244.1 1.9 1.0 1 0 0 1 1 1 1 SURF4 family DUF4267 PF14087.6 EGG02855.1 - 0.019 15.0 1.0 0.037 14.1 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) DoxX PF07681.12 EGG02855.1 - 0.075 13.6 15.7 0.85 10.3 0.0 3.3 2 1 0 2 2 2 0 DoxX DUF2207 PF09972.9 EGG02855.1 - 0.13 11.0 1.5 6.1 5.5 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Mucin-like PF16058.5 EGG02855.1 - 3.1 8.0 11.1 5.7 7.1 11.1 1.4 1 0 0 1 1 1 0 Mucin-like Peptidase_S10 PF00450.22 EGG02856.1 - 6.2e-97 325.7 0.3 7.7e-97 325.3 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Beta_helix PF13229.6 EGG02858.1 - 4.2e-07 29.9 0.1 2.3e-06 27.6 0.1 2.1 1 1 0 1 1 1 1 Right handed beta helix region B_lectin PF01453.24 EGG02858.1 - 2.3e-05 24.9 0.0 0.0024 18.4 0.0 3.1 2 2 1 3 3 3 1 D-mannose binding lectin Glyco_hydro_18 PF00704.28 EGG02859.1 - 4.9e-59 200.6 0.0 6.1e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SAM_2 PF07647.17 EGG02860.1 - 0.034 14.3 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Gemini_BL1 PF00845.19 EGG02862.1 - 0.087 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Geminivirus BL1 movement protein Rgp1 PF08737.10 EGG02863.1 - 1.3e-66 225.6 0.0 4.6e-38 131.5 0.0 2.8 2 1 1 3 3 3 2 Rgp1 Arrestin_C PF02752.22 EGG02863.1 - 3e-08 34.2 0.2 0.13 12.7 0.0 3.5 3 0 0 3 3 3 3 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGG02863.1 - 0.00012 22.1 0.0 0.0015 18.6 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain RRM_1 PF00076.22 EGG02865.1 - 2.6e-10 40.0 4.6 1.2e-07 31.5 0.2 4.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1389 PF07146.11 EGG02867.1 - 0.025 13.9 0.0 0.047 13.0 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1389) Peptidase_S8 PF00082.22 EGG02868.1 - 1.7e-48 165.4 2.2 2.4e-48 164.9 2.2 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EGG02868.1 - 1.9e-11 44.6 0.2 3.9e-11 43.6 0.2 1.6 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 EGG02868.1 - 0.0023 17.9 0.0 0.014 15.4 0.0 2.3 3 0 0 3 3 3 1 PA domain DUF2880 PF11082.8 EGG02870.1 - 0.081 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) Flu_NS2 PF00601.19 EGG02871.1 - 1.5 9.1 4.7 1.5 9.2 0.9 2.8 3 0 0 3 3 3 0 Influenza non-structural protein (NS2) Cation_ATPase PF13246.6 EGG02877.1 - 0.038 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF3195 PF11424.8 EGG02882.1 - 0.1 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGG02882.1 - 0.15 11.0 0.4 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 NUC194 domain DUF2170 PF09938.9 EGG02882.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) CAP_N PF01213.19 EGG02885.1 - 2.1 7.8 12.0 3.7 6.9 12.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DASH_Dad3 PF08656.10 EGG02886.1 - 0.0051 16.9 1.4 0.11 12.6 1.4 2.3 1 1 0 1 1 1 1 DASH complex subunit Dad3 Sec2p PF06428.11 EGG02888.1 - 1.4e-14 53.8 8.4 1.4e-14 53.8 8.4 2.8 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p DUF1635 PF07795.11 EGG02888.1 - 0.024 14.5 0.8 0.024 14.5 0.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1635) DUF5446 PF17522.2 EGG02888.1 - 0.065 13.4 0.5 0.065 13.4 0.5 3.4 2 1 0 3 3 3 0 Family of unknown function (DUF5446) DUF4201 PF13870.6 EGG02888.1 - 1.9 8.2 17.9 0.32 10.7 3.3 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4201) Uso1_p115_C PF04871.13 EGG02888.1 - 5.1 7.5 23.6 31 4.9 16.6 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Malate_synthase PF01274.22 EGG02889.1 - 4.6e-212 704.9 0.0 5.3e-212 704.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase RSN1_7TM PF02714.15 EGG02890.1 - 8.7e-58 195.8 31.6 1.2e-50 172.3 16.1 2.9 1 1 1 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGG02890.1 - 1.1e-26 93.5 4.6 1.1e-26 93.5 4.6 3.3 5 0 0 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGG02890.1 - 1.2e-21 77.7 0.1 1.7e-21 77.3 0.1 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PDDEXK_6 PF04720.12 EGG02891.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 PDDEXK-like family of unknown function ABC2_membrane PF01061.24 EGG02894.1 - 1.7e-58 197.5 59.2 4.1e-30 104.8 32.4 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGG02894.1 - 3.2e-17 63.3 0.0 2e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGG02894.1 - 3.1e-16 59.1 6.9 9.7e-11 41.4 0.0 3.5 3 1 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EGG02894.1 - 9.3e-07 29.4 0.0 2.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 EGG02894.1 - 0.0041 17.0 0.2 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG02894.1 - 0.021 14.3 0.0 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MAP65_ASE1 PF03999.12 EGG02895.1 - 2e-45 155.6 8.1 3.3e-44 151.6 8.1 2.3 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Snapin_Pallidin PF14712.6 EGG02895.1 - 0.16 12.4 1.7 0.85 10.1 1.7 2.3 1 0 0 1 1 1 0 Snapin/Pallidin ATG16 PF08614.11 EGG02895.1 - 3.7 7.7 12.5 1.4 9.1 0.2 3.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) SOG2 PF10428.9 EGG02895.1 - 4.6 6.3 24.8 11 5.1 24.8 1.7 1 0 0 1 1 1 0 RAM signalling pathway protein NAT PF04768.13 EGG02896.1 - 1.8e-43 148.1 0.0 3.1e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EGG02896.1 - 6.1e-31 107.4 0.0 1.8e-30 105.8 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EGG02896.1 - 2.2e-26 93.0 0.0 3.4e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family Dor1 PF04124.12 EGG02896.1 - 0.055 12.1 0.0 0.094 11.4 0.0 1.3 1 0 0 1 1 1 0 Dor1-like family DapB_N PF01113.20 EGG02896.1 - 0.18 11.9 0.0 0.72 10.0 0.0 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Fungal_trans PF04082.18 EGG02898.1 - 6.2e-16 58.2 0.4 1.2e-15 57.2 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 EGG02899.1 - 7.3e-11 41.6 0.0 0.00023 20.3 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EGG02899.1 - 7.6e-06 25.9 8.6 7.6e-06 25.9 8.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KDZ PF18758.1 EGG02901.1 - 1.1e-19 70.9 0.2 1.3e-19 70.7 0.2 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Cytokin_check_N PF10407.9 EGG02902.1 - 0.012 15.6 0.0 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Fungal_trans PF04082.18 EGG02903.1 - 1.3e-12 47.3 0.3 2.1e-12 46.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGG02903.1 - 0.00011 22.3 8.1 0.0002 21.4 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TetR PF13972.6 EGG02903.1 - 0.018 14.8 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial transcriptional repressor Fungal_trans PF04082.18 EGG02906.1 - 1.3e-13 50.6 0.6 2e-13 50.0 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGG02906.1 - 0.00062 19.8 8.0 0.0012 18.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CD34_antigen PF06365.12 EGG02907.1 - 0.012 15.2 0.1 0.024 14.2 0.0 1.5 1 1 1 2 2 2 0 CD34/Podocalyxin family LapA_dom PF06305.11 EGG02907.1 - 0.1 12.4 1.0 0.16 11.8 1.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SCHIP-1 PF10148.9 EGG02908.1 - 0.22 11.1 0.8 0.31 10.6 0.8 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Ribosomal_L38e PF01781.18 EGG02909.1 - 4.6e-28 97.1 0.8 5.4e-28 96.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family NAM-associated PF14303.6 EGG02910.1 - 9e-24 85.1 3.0 1.2e-23 84.7 3.0 1.1 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Ras PF00071.22 EGG02911.1 - 8.1e-34 116.6 0.2 9.7e-34 116.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG02911.1 - 1.5e-25 89.7 0.1 2.3e-25 89.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG02911.1 - 5.9e-09 35.6 0.1 7.1e-09 35.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG02911.1 - 8.7e-07 28.5 0.2 1.1e-06 28.2 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EGG02911.1 - 0.0021 17.0 0.2 0.96 8.2 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) TniB PF05621.11 EGG02911.1 - 0.013 14.9 0.0 2 7.8 0.0 2.4 2 1 0 2 2 2 0 Bacterial TniB protein G-alpha PF00503.20 EGG02911.1 - 0.029 13.5 3.6 0.066 12.4 0.1 2.4 1 1 2 3 3 3 0 G-protein alpha subunit MMR_HSR1 PF01926.23 EGG02911.1 - 0.096 12.8 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 EGG02911.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pterin_bind PF00809.22 EGG02912.1 - 4.3e-34 118.3 0.1 5.9e-34 117.8 0.1 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EGG02912.1 - 1.8e-15 57.4 0.0 3.2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) adh_short PF00106.25 EGG02913.1 - 1.3e-19 70.4 2.0 1.5e-19 70.2 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG02913.1 - 5.3e-15 55.6 1.4 6.5e-15 55.3 1.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG02913.1 - 1.1e-06 28.7 0.6 1.4e-06 28.3 0.6 1.1 1 0 0 1 1 1 1 KR domain PALP PF00291.25 EGG02913.1 - 0.0067 15.9 0.1 0.0076 15.7 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 EGG02913.1 - 0.0073 16.3 1.3 0.012 15.5 0.8 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Ldh_1_N PF00056.23 EGG02913.1 - 0.008 16.3 1.0 0.011 15.9 1.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EGG02913.1 - 0.01 15.7 1.1 0.017 15.0 1.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltr_RsmB-F PF01189.17 EGG02913.1 - 0.071 12.7 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F MIP PF00230.20 EGG02914.1 - 0.0087 15.8 8.4 0.01 15.6 3.9 2.4 1 1 1 2 2 2 2 Major intrinsic protein DUF1730 PF08331.10 EGG02915.1 - 0.0081 16.0 0.3 2.1 8.3 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1730) DUF3245 PF11595.8 EGG02915.1 - 2.8 8.4 6.6 6.3 7.3 6.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) MIP PF00230.20 EGG02916.1 - 0.0032 17.2 1.1 0.027 14.2 0.1 2.1 2 0 0 2 2 2 2 Major intrinsic protein Ribosomal_L13 PF00572.18 EGG02917.1 - 6.9e-44 149.1 0.1 8.8e-44 148.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 ResIII PF04851.15 EGG02918.1 - 7.9e-22 78.0 0.0 1.9e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGG02918.1 - 3.8e-20 72.3 0.1 9.3e-20 71.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG02918.1 - 1.9e-18 66.9 0.0 4.1e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGG02918.1 - 0.00049 19.8 0.0 0.00098 18.9 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 EGG02918.1 - 0.0063 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF4808 PF16066.5 EGG02918.1 - 0.1 13.1 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) Glycophorin_A PF01102.18 EGG02919.1 - 0.0062 16.8 1.5 0.0062 16.8 1.5 2.2 1 1 1 2 2 2 1 Glycophorin A DUF4834 PF16118.5 EGG02919.1 - 0.28 12.2 0.8 0.58 11.2 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM154 PF15102.6 EGG02919.1 - 0.7 9.8 10.8 2.3 8.1 8.9 2.5 1 1 1 2 2 2 0 TMEM154 protein family Peptidase_M56 PF05569.11 EGG02920.1 - 0.016 14.4 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 ABC2_membrane_3 PF12698.7 EGG02920.1 - 0.028 13.5 0.2 0.037 13.1 0.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein PIRT PF15099.6 EGG02920.1 - 0.078 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family CCB1 PF12046.8 EGG02920.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B p450 PF00067.22 EGG02922.1 - 9.7e-52 176.2 0.0 1.3e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Coat_F PF07875.12 EGG02923.1 - 0.0061 16.8 0.5 0.018 15.3 0.5 1.8 1 0 0 1 1 1 1 Coat F domain DUF4404 PF14357.6 EGG02923.1 - 0.074 13.7 0.5 0.69 10.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Resolvase PF00239.21 EGG02923.1 - 0.24 11.5 3.1 0.95 9.6 0.0 3.3 4 1 1 5 5 5 0 Resolvase, N terminal domain ER_lumen_recept PF00810.18 EGG02926.1 - 2.9e-05 24.9 0.7 4.7e-05 24.3 0.7 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor OGG_N PF07934.12 EGG02927.1 - 3.9e-27 94.7 4.7 3.9e-27 94.7 4.7 1.8 2 1 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EGG02927.1 - 5.5e-13 49.3 0.0 9.1e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein MAPKK1_Int PF08923.10 EGG02927.1 - 0.13 12.1 0.9 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 Mitogen-activated protein kinase kinase 1 interacting AdoHcyase PF05221.17 EGG02928.1 - 7.1e-133 442.4 0.0 6.5e-74 248.8 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EGG02928.1 - 5.9e-84 280.0 1.0 9.9e-84 279.3 1.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGG02928.1 - 1.5e-08 34.2 0.1 2.9e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EGG02928.1 - 0.0011 18.6 0.2 0.002 17.7 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EGG02928.1 - 0.0022 18.2 0.1 0.005 17.1 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 EGG02928.1 - 0.0044 16.9 0.2 0.0079 16.1 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EGG02928.1 - 0.0097 15.7 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 EGG02928.1 - 0.013 16.0 0.2 0.032 14.7 0.2 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 EGG02928.1 - 0.017 15.7 0.3 0.04 14.5 0.3 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGG02928.1 - 0.028 14.5 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TetR_N PF00440.23 EGG02928.1 - 0.16 11.8 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Rap1_C PF11626.8 EGG02929.1 - 0.0061 16.6 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3452 PF11934.8 EGG02929.1 - 0.01 15.4 0.3 0.017 14.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Vanabin-2 PF11437.8 EGG02933.1 - 0.19 11.9 1.4 0.31 11.2 1.4 1.3 1 0 0 1 1 1 0 Vanadium-binding protein 2 DUF4983 PF16356.5 EGG02935.1 - 0.039 14.8 0.2 0.8 10.6 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4983) Rad60-SLD_2 PF13881.6 EGG02936.1 - 2.3e-12 47.0 0.0 4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGG02936.1 - 0.0064 16.2 0.0 0.016 15.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family Lactamase_B_2 PF12706.7 EGG02938.1 - 3.5e-14 52.8 0.0 1.1e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EGG02938.1 - 1.7e-10 40.4 0.0 3.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 EGG02938.1 - 0.00015 21.8 0.1 0.00061 19.8 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily CMV_1a PF12467.8 EGG02939.1 - 0.21 11.9 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family ANTH PF07651.16 EGG02940.1 - 1.9e-10 40.2 2.2 4.8e-06 25.8 0.0 3.2 2 1 2 4 4 4 2 ANTH domain p450 PF00067.22 EGG02942.1 - 6.3e-17 61.5 0.0 2.3e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 BRE PF06113.12 EGG02942.1 - 0.045 12.6 0.1 0.066 12.0 0.1 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) SOCS_box PF07525.16 EGG02943.1 - 0.014 15.8 0.3 0.028 14.8 0.3 1.5 1 0 0 1 1 1 0 SOCS box UPF0227 PF05728.12 EGG02946.1 - 0.023 14.6 0.1 0.05 13.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PBP PF01161.20 EGG02948.1 - 1.1e-14 54.8 0.1 1.3e-14 54.6 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glutaredoxin PF00462.24 EGG02949.1 - 1.8e-15 56.9 0.0 2.6e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DSBA PF01323.20 EGG02949.1 - 0.019 14.8 0.3 1.6 8.5 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF836 PF05768.14 EGG02949.1 - 0.032 14.6 0.0 0.041 14.3 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 EGG02949.1 - 0.053 14.0 0.0 0.076 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.6 EGG02949.1 - 0.18 12.0 0.0 1.1 9.3 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin zf-C2H2 PF00096.26 EGG02951.1 - 3.9e-05 23.9 0.5 3.9e-05 23.9 0.5 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG02951.1 - 0.00089 19.9 1.6 0.0014 19.3 0.3 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGG02951.1 - 0.0098 16.2 0.4 0.028 14.7 0.4 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EGG02951.1 - 0.013 15.5 1.3 0.039 13.9 1.3 1.9 1 1 0 1 1 1 0 C2H2-type zinc finger Solute_trans_a PF03619.16 EGG02952.1 - 2.7e-89 299.2 10.7 3.4e-89 298.9 10.7 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SNARE PF05739.19 EGG02954.1 - 5.1e-05 23.2 0.7 7.6e-05 22.6 0.1 1.6 2 0 0 2 2 2 1 SNARE domain SPECT1 PF18680.1 EGG02954.1 - 0.013 15.1 0.0 0.014 15.0 0.0 1.0 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 RasGAP_C PF03836.15 EGG02954.1 - 0.054 13.6 0.0 0.062 13.4 0.0 1.0 1 0 0 1 1 1 0 RasGAP C-terminus CCDC144C PF14915.6 EGG02954.1 - 0.057 12.5 0.9 0.065 12.3 0.9 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Synaptobrevin PF00957.21 EGG02954.1 - 0.48 10.3 3.4 0.55 10.1 2.3 1.7 1 1 0 1 1 1 0 Synaptobrevin Mo25 PF08569.11 EGG02955.1 - 3.4e-124 414.5 12.9 4.5e-124 414.1 12.9 1.2 1 0 0 1 1 1 1 Mo25-like Dala_Dala_lig_C PF07478.13 EGG02955.1 - 0.11 12.0 0.5 0.24 10.9 0.1 1.6 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Abhydrolase_2 PF02230.16 EGG02956.1 - 1.7e-57 194.7 0.0 2e-57 194.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EGG02956.1 - 5.6e-09 35.6 0.1 0.0013 18.1 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG02956.1 - 2.6e-05 24.9 1.4 9.7e-05 23.1 1.6 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGG02956.1 - 0.00017 21.3 0.0 0.00029 20.5 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EGG02956.1 - 0.00082 19.1 0.1 0.063 12.9 0.1 2.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 EGG02956.1 - 0.0047 16.6 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 EGG02956.1 - 0.009 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EGG02956.1 - 0.023 14.2 0.1 0.18 11.3 0.0 2.3 2 1 1 3 3 3 0 Prolyl oligopeptidase family Cutinase PF01083.22 EGG02956.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Cutinase TBCA PF02970.16 EGG02958.1 - 2.2e-19 69.5 7.3 3.1e-19 69.1 6.7 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor A Med19 PF10278.9 EGG02958.1 - 0.0078 16.2 1.6 0.011 15.6 1.6 1.2 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 HD_5 PF13487.6 EGG02958.1 - 0.019 15.2 0.3 0.063 13.5 0.0 1.9 2 0 0 2 2 2 0 HD domain Glyco_hydro_18 PF00704.28 EGG02959.1 - 6.5e-59 200.2 0.3 7.4e-59 200.0 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_114 PF03537.13 EGG02959.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 Alpha-amylase PF00128.24 EGG02960.1 - 9.4e-15 55.0 0.0 2.1e-14 53.9 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain EF-hand_1 PF00036.32 EGG02962.1 - 1.5e-41 136.9 10.8 9.6e-10 37.3 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGG02962.1 - 6.6e-35 119.4 1.6 4.1e-18 65.6 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGG02962.1 - 1.7e-31 107.9 10.2 6.3e-15 54.8 0.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGG02962.1 - 2.3e-31 105.0 4.4 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGG02962.1 - 8.9e-28 94.5 7.7 1.2e-06 27.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGG02962.1 - 7.8e-15 54.9 0.1 3.2e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGG02962.1 - 4.1e-10 39.6 0.2 6.2e-05 22.9 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGG02962.1 - 9.4e-08 32.4 0.0 0.0028 18.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EGG02962.1 - 8.5e-06 25.7 0.5 0.32 11.1 0.0 3.2 3 1 1 4 4 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 EGG02962.1 - 2.2e-05 24.5 3.1 0.0064 16.7 0.1 3.1 1 1 3 4 4 4 1 Dockerin type I domain EFhand_Ca_insen PF08726.10 EGG02962.1 - 8.1e-05 22.6 0.9 0.00025 21.1 0.1 2.1 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 EGG02962.1 - 0.00022 22.1 0.0 0.055 14.3 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain Caleosin PF05042.13 EGG02962.1 - 0.00054 19.9 0.6 0.43 10.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein DUF1103 PF06513.11 EGG02962.1 - 0.00066 19.4 1.7 0.00069 19.3 1.7 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.13 EGG02962.1 - 0.0031 17.5 0.1 1.9 8.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 EGG02962.1 - 0.0042 17.8 0.2 4.3 8.2 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Poly_export PF02563.16 EGG02962.1 - 0.0057 16.8 0.0 0.87 9.9 0.0 3.0 1 1 2 3 3 3 1 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 EGG02962.1 - 0.0065 16.9 0.0 2.7 8.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) MotA_activ PF09114.10 EGG02962.1 - 0.0098 16.0 0.3 0.19 11.9 0.1 2.3 1 1 0 2 2 2 1 Transcription factor MotA, activation domain DUF5580 PF17743.1 EGG02962.1 - 0.014 14.0 0.0 0.015 13.9 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) RNA_pol_Rpb4 PF03874.16 EGG02962.1 - 0.014 15.7 0.1 1.3 9.3 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb4 DUF1296 PF06972.11 EGG02962.1 - 0.07 13.3 0.6 4.2 7.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) RuvA_C PF07499.13 EGG02962.1 - 0.073 13.5 0.1 4.6 7.8 0.1 2.9 3 0 0 3 3 3 0 RuvA, C-terminal domain Fe_hyd_lg_C PF02906.14 EGG02962.1 - 0.075 12.7 0.3 0.17 11.5 0.3 1.6 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain dCache_2 PF08269.11 EGG02962.1 - 0.1 11.8 0.1 1 8.5 0.1 2.2 1 1 1 2 2 2 0 Cache domain EF-hand_14 PF17959.1 EGG02962.1 - 0.11 12.9 0.1 18 5.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 EGG02963.1 - 2.7e-32 107.9 10.2 1.4e-09 36.8 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGG02963.1 - 4.4e-29 100.7 1.5 1.1e-13 51.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGG02963.1 - 3.4e-25 85.8 6.5 2.3e-09 36.4 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGG02963.1 - 1.8e-24 85.3 9.3 2.7e-11 43.1 0.6 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGG02963.1 - 1.3e-21 75.1 7.8 3.8e-06 26.1 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 EGG02963.1 - 4.8e-12 45.7 0.3 4.1e-05 23.5 0.1 2.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGG02963.1 - 2e-09 37.6 0.2 2.9e-05 24.3 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGG02963.1 - 6.3e-09 36.2 0.0 0.0036 17.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EGG02963.1 - 9e-07 28.8 0.2 0.1 12.7 0.0 3.1 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 EGG02963.1 - 0.00011 22.3 4.8 0.14 12.4 0.2 3.1 2 2 1 3 3 3 3 Dockerin type I domain DUF3349 PF11829.8 EGG02963.1 - 0.00055 20.7 0.3 0.48 11.2 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) SapB_1 PF05184.15 EGG02963.1 - 0.00075 19.5 0.7 0.078 13.0 0.0 3.3 4 0 0 4 4 4 1 Saposin-like type B, region 1 EFhand_Ca_insen PF08726.10 EGG02963.1 - 0.0043 17.1 0.1 0.034 14.2 0.0 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.13 EGG02963.1 - 0.013 15.4 0.2 0.13 12.2 0.0 2.3 1 1 0 2 2 2 0 Caleosin related protein MotA_activ PF09114.10 EGG02963.1 - 0.017 15.2 0.2 1.3 9.2 0.0 2.2 1 1 1 2 2 2 0 Transcription factor MotA, activation domain EF-hand_11 PF08976.11 EGG02963.1 - 0.049 14.5 0.0 0.61 11.0 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain RNA_pol_Rpb4 PF03874.16 EGG02963.1 - 0.068 13.5 0.5 2.3 8.6 0.1 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb4 TerB PF05099.13 EGG02963.1 - 0.073 13.0 0.2 9.2 6.2 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB Mst1_SARAH PF11629.8 EGG02963.1 - 0.08 13.0 0.1 0.36 11.0 0.1 2.1 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF1296 PF06972.11 EGG02963.1 - 0.087 13.0 0.8 11 6.2 0.1 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF1296) SurA_N_2 PF13623.6 EGG02963.1 - 0.11 12.4 1.1 0.63 9.9 0.3 2.2 1 1 1 2 2 2 0 SurA N-terminal domain PGM_PMM_III PF02880.16 EGG02963.1 - 0.13 12.5 0.1 13 6.0 0.0 2.8 1 1 2 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III EF-hand_1 PF00036.32 EGG02964.1 - 4.8e-37 122.7 13.1 6e-09 34.8 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGG02964.1 - 2.1e-33 114.6 2.6 2.5e-18 66.3 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGG02964.1 - 6.1e-30 100.6 4.8 1.3e-08 34.1 0.0 4.6 4 2 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGG02964.1 - 1.2e-25 89.1 10.7 3.5e-11 42.8 0.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGG02964.1 - 2.2e-22 77.5 13.1 2.3e-06 26.8 0.2 4.5 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.6 EGG02964.1 - 3.8e-13 49.6 0.0 1.1e-06 28.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGG02964.1 - 8.6e-11 41.7 0.7 3.3e-05 23.8 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGG02964.1 - 3.7e-07 30.4 0.0 0.0062 16.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EGG02964.1 - 3.1e-06 28.0 0.0 0.0037 18.1 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 EGG02964.1 - 2e-05 24.7 1.1 0.017 15.3 0.1 2.7 1 1 2 3 3 3 2 Dockerin type I domain UPF0154 PF03672.13 EGG02964.1 - 3.4e-05 23.8 0.1 0.13 12.3 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 EGG02964.1 - 0.0014 18.6 1.8 5.2 7.0 0.0 3.7 1 1 3 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 EGG02964.1 - 0.0059 17.4 0.3 3.2 8.6 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF4497 PF14924.6 EGG02964.1 - 0.011 16.2 0.1 2.2 8.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) EFhand_Ca_insen PF08726.10 EGG02964.1 - 0.037 14.1 1.2 0.12 12.5 0.1 2.3 2 1 0 2 2 2 0 Ca2+ insensitive EF hand TerB PF05099.13 EGG02964.1 - 0.045 13.7 0.3 8.3 6.4 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB HHA PF05321.11 EGG02964.1 - 0.055 13.8 0.7 0.19 12.0 0.1 2.2 2 0 0 2 2 2 0 Haemolysin expression modulating protein Beta-lactamase2 PF13354.6 EGG02964.1 - 0.065 12.8 0.0 0.25 10.9 0.0 1.8 1 1 1 2 2 2 0 Beta-lactamase enzyme family FGAR-AT_linker PF18072.1 EGG02964.1 - 0.066 13.8 0.6 5.9 7.5 0.0 2.7 2 2 1 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain DUF5580 PF17743.1 EGG02964.1 - 0.099 11.2 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF2267 PF10025.9 EGG02964.1 - 0.11 12.7 0.0 0.32 11.3 0.0 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Alpha-amylase PF00128.24 EGG02966.1 - 1.3e-18 67.7 1.9 3.4e-16 59.7 0.7 3.0 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EGG02966.1 - 2.9e-14 53.4 0.0 4.9e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EGG02966.1 - 1.8e-05 24.4 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 VCBS PF13517.6 EGG02966.1 - 0.023 15.3 2.4 0.095 13.3 2.4 2.1 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF1461 PF07314.11 EGG02966.1 - 0.41 10.5 2.7 0.34 10.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) YIF1 PF03878.15 EGG02967.1 - 5.8e-91 304.3 0.1 6.5e-91 304.1 0.1 1.0 1 0 0 1 1 1 1 YIF1 YtpI PF14007.6 EGG02967.1 - 0.048 13.8 2.8 0.29 11.3 0.7 2.6 2 1 0 2 2 2 0 YtpI-like protein DUF1981 PF09324.10 EGG02968.1 - 0.02 14.7 0.1 0.044 13.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) DUF5104 PF17117.5 EGG02968.1 - 0.04 14.4 0.1 0.097 13.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5104) baeRF_family12 PF18856.1 EGG02968.1 - 4 8.0 7.7 1.6 9.3 0.5 2.9 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 Mito_carr PF00153.27 EGG02969.1 - 1.9e-54 181.6 3.8 1.1e-19 70.1 0.0 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 EGG02969.1 - 0.00014 21.1 1.3 0.022 13.9 0.1 2.9 2 1 0 3 3 3 2 Gammaproteobacterial serine protease LRR_4 PF12799.7 EGG02970.1 - 0.03 14.8 9.2 2.8 8.5 0.2 5.5 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) Trypan_PARP PF05887.11 EGG02970.1 - 0.03 14.3 18.2 0.052 13.5 18.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) LRR_9 PF14580.6 EGG02972.1 - 0.046 13.2 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat Frag1 PF10277.9 EGG02974.1 - 0.0031 17.1 1.8 0.0031 17.1 1.8 1.7 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family DUF3149 PF11346.8 EGG02974.1 - 0.017 14.7 2.0 0.075 12.7 2.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) PIP49_N PF14875.6 EGG02974.1 - 0.78 9.6 3.0 1.8 8.4 3.0 1.5 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 UQ_con PF00179.26 EGG02981.1 - 3.1e-46 156.5 0.0 3.6e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGG02981.1 - 0.00099 18.8 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGG02981.1 - 0.011 15.6 0.1 0.023 14.6 0.1 1.6 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 EGG02981.1 - 0.072 13.4 0.1 0.16 12.2 0.1 1.6 1 1 1 2 2 2 0 RWD domain BPL_LplA_LipB PF03099.19 EGG02982.1 - 9.4e-06 25.6 0.2 0.00013 21.8 0.2 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family eIF-1a PF01176.19 EGG02983.1 - 1e-21 76.5 0.0 1.5e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Peroxidase_2 PF01328.17 EGG02984.1 - 3.1e-14 54.0 0.8 4.1e-10 40.5 0.0 2.0 1 1 1 2 2 2 2 Peroxidase, family 2 Sel1 PF08238.12 EGG02986.1 - 1.2e-43 146.6 17.3 2.8e-08 34.1 0.2 8.0 8 0 0 8 8 8 7 Sel1 repeat Ribosomal_L24e PF01246.20 EGG02987.1 - 1.4e-30 105.3 1.0 2.8e-30 104.3 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e DUF4637 PF15470.6 EGG02988.1 - 0.0047 16.7 0.3 0.0059 16.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) Pur_ac_phosph_N PF16656.5 EGG02989.1 - 0.0038 17.8 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Retrotran_gag_2 PF14223.6 EGG02991.1 - 1.9e-09 37.3 1.7 4.2e-09 36.2 0.3 2.1 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type Cir_N PF10197.9 EGG02992.1 - 0.045 13.9 0.3 0.045 13.9 0.3 3.6 4 0 0 4 4 4 0 N-terminal domain of CBF1 interacting co-repressor CIR Alpha-amylase PF00128.24 EGG02993.1 - 3.9e-15 56.3 0.0 1.3e-14 54.5 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF5486 PF17588.2 EGG02994.1 - 0.14 12.1 0.2 0.47 10.4 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5486) Mito_carr PF00153.27 EGG02995.1 - 2.8e-60 200.3 4.8 9.7e-20 70.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MatC_N PF07158.11 EGG02995.1 - 0.11 12.5 0.6 0.29 11.2 0.1 1.9 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus RNase_PH PF01138.21 EGG02996.1 - 3.9e-18 66.2 0.0 6.1e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Histone PF00125.24 EGG02998.1 - 4.1e-50 169.5 2.9 4.6e-50 169.4 2.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGG02998.1 - 2.2e-05 24.8 0.0 3.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGG02998.1 - 0.00011 22.3 0.1 0.00021 21.4 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EGG02998.1 - 0.00015 22.4 1.3 0.00018 22.1 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EGG02998.1 - 0.0036 17.5 0.0 0.0071 16.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGG02998.1 - 0.027 14.6 0.2 0.044 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGG02998.1 - 0.027 14.5 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF1057 PF06342.12 EGG03000.1 - 0.0051 15.9 0.0 0.039 13.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) PCRF PF03462.18 EGG03001.1 - 7.3e-42 143.4 0.9 1.4e-41 142.5 0.1 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EGG03001.1 - 9.7e-36 122.2 7.1 1.9e-35 121.3 7.1 1.5 1 0 0 1 1 1 1 RF-1 domain SBF PF01758.16 EGG03002.1 - 5.6e-36 124.0 9.0 6.7e-36 123.8 7.9 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family Herpes_glycop_D PF01537.17 EGG03004.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain SRP14 PF02290.15 EGG03005.1 - 6.7 7.1 6.5 0.97 9.8 0.5 2.5 3 0 0 3 3 3 0 Signal recognition particle 14kD protein Peptidase_M24 PF00557.24 EGG03006.1 - 2.6e-46 158.0 0.0 4.2e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 EGG03006.1 - 2.3e-41 141.6 0.0 6.5e-41 140.1 0.0 1.8 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EGG03006.1 - 1.3e-24 86.0 0.7 3.1e-24 84.8 0.7 1.7 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EGG03006.1 - 2.9e-13 50.6 0.0 9e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Oxysterol_BP PF01237.18 EGG03007.1 - 1.2e-38 132.9 0.7 1.9e-35 122.4 0.7 3.2 1 1 0 1 1 1 1 Oxysterol-binding protein MBOAT_2 PF13813.6 EGG03008.1 - 5.3e-13 49.1 2.2 1.5e-12 47.6 2.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Amino_oxidase PF01593.24 EGG03009.1 - 6.3e-49 167.5 0.0 9e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGG03009.1 - 2.2e-10 40.6 0.0 5.2e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG03009.1 - 2e-05 24.3 0.0 0.00017 21.3 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG03009.1 - 9.2e-05 21.3 0.9 0.024 13.3 0.0 2.7 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 EGG03009.1 - 0.00042 19.6 0.0 0.00083 18.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EGG03009.1 - 0.00094 19.2 0.1 0.0077 16.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EGG03009.1 - 0.00094 18.4 0.0 0.0094 15.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EGG03009.1 - 0.0017 18.9 2.3 2 9.0 0.4 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGG03009.1 - 0.0024 17.2 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGG03009.1 - 0.033 13.1 0.0 0.068 12.0 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 EGG03009.1 - 0.042 13.0 0.2 7.5 5.6 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Nnf1 PF03980.14 EGG03009.1 - 0.06 13.7 0.2 0.16 12.4 0.2 1.7 1 0 0 1 1 1 0 Nnf1 FAD_oxidored PF12831.7 EGG03009.1 - 0.11 11.9 0.0 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGG03009.1 - 0.12 11.6 1.6 0.15 11.3 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGG03009.1 - 0.2 10.8 0.0 2.7 7.2 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain EntA_Immun PF08951.10 EGG03009.1 - 1.6 9.1 7.0 3.9 7.9 0.0 3.8 4 1 0 4 4 4 0 Enterocin A Immunity Baculo_PEP_C PF04513.12 EGG03009.1 - 6.1 6.9 8.3 0.93 9.5 0.7 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NAS PF03059.16 EGG03010.1 - 0.1 11.9 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Nicotianamine synthase protein HSBP1 PF06825.12 EGG03010.1 - 0.14 12.1 5.4 1.3 9.0 0.5 2.5 1 1 1 2 2 2 0 Heat shock factor binding protein 1 p450 PF00067.22 EGG03011.1 - 4.7e-59 200.3 0.0 6.3e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGG03014.1 - 1.7e-63 215.0 0.0 2.4e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD-oxidase_C PF02913.19 EGG03015.1 - 2.7e-52 177.9 0.0 3.4e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGG03015.1 - 6.1e-32 110.3 0.3 9.8e-32 109.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain CagY_I PF14585.6 EGG03016.1 - 0.018 15.1 3.9 0.22 11.7 0.7 2.5 2 0 0 2 2 2 0 CagY type 1 repeat CCDC53 PF10152.9 EGG03017.1 - 0.51 10.7 3.8 0.75 10.2 3.8 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Med25 PF11232.8 EGG03018.1 - 2.4e-08 34.1 0.0 3.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 25 PTOV activation and synapsin 2 4HBT PF03061.22 EGG03020.1 - 9.3e-10 38.7 0.3 1.6e-09 38.0 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.6 EGG03020.1 - 3.1e-07 30.9 0.0 4.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 EGG03020.1 - 0.01 15.2 0.2 0.02 14.2 0.2 1.5 2 0 0 2 2 2 0 Acyl-ACP thioesterase Tcp10_C PF07202.13 EGG03021.1 - 0.19 11.7 0.0 0.25 11.3 0.0 1.1 1 0 0 1 1 1 0 T-complex protein 10 C-terminus IMUP PF15761.5 EGG03021.1 - 2.9 8.6 8.5 4.1 8.1 8.5 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Alpha_kinase PF02816.18 EGG03022.1 - 7.3e-11 42.5 0.8 1.7e-10 41.4 0.8 1.6 1 0 0 1 1 1 1 Alpha-kinase family Usp PF00582.26 EGG03023.1 - 9.4e-20 71.6 1.4 1.5e-19 70.9 0.1 1.9 2 0 0 2 2 2 1 Universal stress protein family DNA_pol_phi PF04931.13 EGG03023.1 - 0.96 7.5 11.7 1.6 6.8 11.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi ThiF PF00899.21 EGG03025.1 - 1.9e-39 135.5 0.0 3e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EGG03025.1 - 0.022 15.0 0.3 0.15 12.3 0.1 2.3 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF1912 PF08930.10 EGG03025.1 - 0.094 12.9 0.5 3.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) DUF2362 PF10154.9 EGG03025.1 - 0.12 11.3 0.3 0.17 10.8 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Polysacc_deac_1 PF01522.21 EGG03026.1 - 1.1e-28 99.6 0.0 1.7e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGG03026.1 - 8.6e-05 21.9 0.0 0.00022 20.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 NUDIX PF00293.28 EGG03027.1 - 1.5e-12 47.7 0.0 2.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EGG03027.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) Polysacc_deac_1 PF01522.21 EGG03028.1 - 5.2e-27 94.2 0.0 9.6e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGG03028.1 - 0.0074 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 RRM_1 PF00076.22 EGG03031.1 - 2.7e-16 59.1 0.0 4.5e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG03031.1 - 1.1e-05 25.0 0.0 2e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EGG03031.1 - 0.094 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 RL domain GLE1 PF07817.13 EGG03034.1 - 3.5e-41 141.1 0.1 7.9e-41 139.9 0.1 1.5 1 0 0 1 1 1 1 GLE1-like protein DUF436 PF04260.12 EGG03034.1 - 0.035 13.7 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF436) adh_short PF00106.25 EGG03038.1 - 2.2e-19 69.7 2.0 2.7e-19 69.4 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG03038.1 - 8.9e-15 54.9 1.4 1.1e-14 54.5 1.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG03038.1 - 1.9e-06 27.9 0.6 2.5e-06 27.5 0.6 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EGG03038.1 - 0.0098 15.9 1.2 0.02 14.9 0.8 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase PALP PF00291.25 EGG03038.1 - 0.011 15.2 0.1 0.013 14.9 0.1 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Ldh_1_N PF00056.23 EGG03038.1 - 0.012 15.7 1.0 0.017 15.2 1.0 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EGG03038.1 - 0.017 15.0 1.1 0.029 14.3 1.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltr_RsmB-F PF01189.17 EGG03038.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F MIP PF00230.20 EGG03040.1 - 0.002 17.9 1.6 0.02 14.6 0.2 2.1 2 0 0 2 2 2 2 Major intrinsic protein Ribosomal_L13 PF00572.18 EGG03041.1 - 4e-44 149.9 0.1 5.1e-44 149.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Apolipoprotein PF01442.18 EGG03043.1 - 0.0003 20.7 0.1 0.00063 19.7 0.1 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EGG03043.1 - 0.00055 20.0 0.9 0.001 19.1 0.9 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 EGG03043.1 - 0.0018 18.4 0.8 0.004 17.3 0.6 1.7 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Lipase_GDSL_3 PF14606.6 EGG03043.1 - 0.0055 16.9 0.1 0.009 16.2 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Use1 PF09753.9 EGG03043.1 - 0.0068 16.2 0.7 0.0098 15.6 0.7 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Fzo_mitofusin PF04799.13 EGG03043.1 - 0.008 15.7 1.6 0.017 14.7 1.6 1.4 1 0 0 1 1 1 1 fzo-like conserved region CSN5_C PF18323.1 EGG03043.1 - 0.01 16.8 0.0 0.15 13.0 0.0 2.6 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Mis14 PF08641.12 EGG03043.1 - 0.018 15.3 0.2 0.05 13.9 0.1 1.7 1 1 0 1 1 1 0 Kinetochore protein Mis14 like Focal_AT PF03623.13 EGG03043.1 - 0.028 14.4 1.3 0.28 11.2 0.4 2.3 2 0 0 2 2 2 0 Focal adhesion targeting region Transcrip_act PF04949.13 EGG03043.1 - 0.031 14.2 0.2 0.058 13.3 0.2 1.4 1 0 0 1 1 1 0 Transcriptional activator Ferritin-like PF12902.7 EGG03043.1 - 0.037 13.9 0.1 0.059 13.2 0.1 1.3 1 0 0 1 1 1 0 Ferritin-like DUF1451 PF07295.11 EGG03043.1 - 0.052 13.6 0.9 0.11 12.6 0.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF4164 PF13747.6 EGG03043.1 - 0.058 13.7 1.4 0.15 12.3 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF1664 PF07889.12 EGG03043.1 - 0.13 12.3 2.5 0.32 11.0 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 EGG03043.1 - 0.26 11.9 3.3 0.41 11.3 0.9 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HSBP1 PF06825.12 EGG03043.1 - 0.9 9.4 4.5 20 5.1 0.0 3.1 2 1 1 3 3 3 0 Heat shock factor binding protein 1 NPV_P10 PF05531.12 EGG03043.1 - 1 9.9 3.4 7.8 7.0 3.4 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CxC5 PF18718.1 EGG03045.1 - 1.9e-24 86.0 2.8 3.1e-24 85.3 2.8 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG03045.1 - 2.4e-09 37.3 3.2 2.9e-09 37.0 0.0 2.5 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases MlaD PF02470.20 EGG03046.1 - 0.061 13.6 0.0 11 6.4 0.0 2.4 2 0 0 2 2 2 0 MlaD protein Fungal_trans PF04082.18 EGG03050.1 - 5.5e-06 25.6 0.1 7.7e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3665 PF12427.8 EGG03051.1 - 0.05 13.3 0.4 0.085 12.6 0.4 1.4 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Rpr2 PF04032.16 EGG03053.1 - 1.9e-21 76.1 0.1 3.6e-21 75.2 0.1 1.5 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Alpha_kinase PF02816.18 EGG03054.1 - 9.3e-06 25.9 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family DZR PF12773.7 EGG03054.1 - 0.18 11.9 13.5 1.3 9.1 2.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon TP_methylase PF00590.20 EGG03058.1 - 1.3e-37 129.8 0.0 1.8e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 EGG03058.1 - 0.078 12.4 1.2 0.14 11.6 1.2 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central RNA_pol_Rpb2_6 PF00562.28 EGG03059.1 - 2.5e-123 412.0 0.0 2.5e-123 412.0 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGG03059.1 - 4.8e-56 189.5 0.3 6.7e-56 189.0 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EGG03059.1 - 5.4e-34 116.5 0.2 2.3e-33 114.5 0.2 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EGG03059.1 - 1.2e-33 116.3 0.3 2.6e-33 115.2 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EGG03059.1 - 3e-25 88.3 0.5 7.9e-25 86.9 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EGG03059.1 - 1.8e-20 72.9 0.0 3.4e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EGG03059.1 - 1.1e-10 41.9 1.2 4.1e-10 40.1 1.2 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PADR1 PF08063.12 EGG03059.1 - 0.14 12.0 2.0 0.38 10.6 2.0 1.8 1 0 0 1 1 1 0 PADR1 (NUC008) domain HSP70 PF00012.20 EGG03060.1 - 1.6e-64 218.2 8.1 1.6e-64 218.2 8.1 4.2 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 EGG03060.1 - 0.00093 18.1 0.2 0.23 10.3 0.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein Pico_P1A PF02226.16 EGG03060.1 - 0.4 10.8 1.8 0.61 10.2 0.2 2.2 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) RRM_1 PF00076.22 EGG03061.1 - 1.1e-05 25.1 0.0 2.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lyase_1 PF00206.20 EGG03062.1 - 4.1e-98 328.6 0.0 6.2e-98 328.0 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EGG03062.1 - 9.6e-26 90.3 0.0 2.3e-25 89.2 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Thymidylate_kin PF02223.17 EGG03063.1 - 2.4e-37 128.4 0.0 3e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 EGG03063.1 - 0.00069 19.9 0.0 0.00096 19.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG03063.1 - 0.0086 16.6 0.0 0.02 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 EGG03063.1 - 0.057 13.3 0.0 0.094 12.6 0.0 1.4 1 1 0 1 1 1 0 Deoxynucleoside kinase GlgS PF08971.11 EGG03063.1 - 0.073 13.1 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Glycogen synthesis protein AAA_14 PF13173.6 EGG03063.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EGG03063.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 CLP1_P PF16575.5 EGG03063.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Na_H_Exchanger PF00999.21 EGG03064.1 - 3e-74 250.1 42.2 4e-74 249.7 42.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RNA_pol_I_A49 PF06870.12 EGG03066.1 - 1.2e-102 343.7 5.7 1.5e-102 343.4 5.7 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Lyase_aromatic PF00221.19 EGG03067.1 - 1.5e-84 284.4 0.5 1.9e-84 284.0 0.5 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Lyase_aromatic PF00221.19 EGG03068.1 - 2.7e-42 145.0 1.6 3e-42 144.9 1.6 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase CFEM PF05730.11 EGG03070.1 - 5.9e-08 32.7 10.6 9.7e-08 32.0 10.6 1.4 1 0 0 1 1 1 1 CFEM domain Microtub_bind PF13931.6 EGG03070.1 - 0.036 14.4 0.5 0.065 13.6 0.5 1.5 1 1 0 1 1 1 0 Kinesin-associated microtubule-binding TSP_1 PF00090.19 EGG03070.1 - 0.59 10.4 6.7 1.1 9.5 6.7 1.5 1 0 0 1 1 1 0 Thrombospondin type 1 domain FeS_assembly_P PF01883.19 EGG03071.1 - 1.2e-12 47.8 0.0 2.8e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein DUF1764 PF08576.10 EGG03073.1 - 0.27 12.2 2.6 0.6 11.0 2.6 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) MscS_TM PF12794.7 EGG03073.1 - 0.29 10.0 1.0 0.4 9.5 1.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4794 PF16042.5 EGG03073.1 - 6.7 7.8 7.8 1.1e+02 3.8 7.8 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4794) DUF1176 PF06674.11 EGG03074.1 - 0.081 12.4 0.1 0.099 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Exo_endo_phos PF03372.23 EGG03075.1 - 4.1e-08 33.0 0.0 1.2e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IATP PF04568.12 EGG03076.1 - 8.6e-08 32.5 0.5 9.1e-08 32.4 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Tektin PF03148.14 EGG03076.1 - 0.004 16.0 0.8 0.0041 15.9 0.8 1.0 1 0 0 1 1 1 1 Tektin family DUF4446 PF14584.6 EGG03076.1 - 0.074 13.0 0.4 0.082 12.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) p450 PF00067.22 EGG03077.1 - 2.2e-48 165.1 0.0 1.1e-37 129.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Omp28 PF11551.8 EGG03077.1 - 0.2 11.5 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein Omp28 TDH PF03347.13 EGG03077.1 - 0.2 11.2 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin S4 PF01479.25 EGG03078.1 - 1.8e-11 43.5 1.0 1.8e-11 43.5 1.0 2.2 3 0 0 3 3 3 1 S4 domain DUF1754 PF08555.10 EGG03080.1 - 4 8.3 20.9 0.27 12.1 6.1 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) SprA-related PF12118.8 EGG03081.1 - 1.6 7.8 29.4 0.037 13.2 18.1 2.3 2 0 0 2 2 2 0 SprA-related family PI3K_1B_p101 PF10486.9 EGG03081.1 - 2.7 5.7 24.6 4.8 4.8 24.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit LCD1 PF09798.9 EGG03081.1 - 3.1 6.2 14.7 5.9 5.3 14.7 1.5 1 0 0 1 1 1 0 DNA damage checkpoint protein RasGEF PF00617.19 EGG03082.1 - 1.1e-31 110.4 0.0 6.3e-31 107.9 0.0 2.3 2 1 0 2 2 2 1 RasGEF domain Gly_radical PF01228.21 EGG03084.1 - 0.04 14.5 0.0 0.098 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycine radical Sacchrp_dh_C PF16653.5 EGG03085.1 - 1.3e-67 228.7 0.0 2.2e-67 228.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EGG03085.1 - 5.6e-16 59.0 0.3 7e-15 55.4 0.0 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 EGG03085.1 - 3.3e-14 53.3 0.0 7.5e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EGG03085.1 - 7.5e-05 22.1 0.1 0.076 12.3 0.0 2.6 1 1 1 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.24 EGG03085.1 - 0.0041 17.5 0.1 0.088 13.2 0.0 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EGG03085.1 - 0.0091 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_7 PF13241.6 EGG03085.1 - 0.05 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DapB_N PF01113.20 EGG03085.1 - 0.077 13.1 0.3 3.1 7.9 0.1 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus SVWC PF15430.6 EGG03086.1 - 0.066 13.5 0.2 0.094 13.0 0.2 1.2 1 0 0 1 1 1 0 Single domain von Willebrand factor type C CobT PF06213.12 EGG03088.1 - 0.056 12.8 5.3 0.077 12.4 5.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIIAH PF12685.7 EGG03088.1 - 0.3 10.9 8.0 0.38 10.5 8.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Zip PF02535.22 EGG03088.1 - 0.37 10.0 4.8 0.36 10.0 4.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGG03088.1 - 0.48 9.1 4.7 0.51 9.0 4.7 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGG03088.1 - 6.1 5.0 8.4 6.7 4.9 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 EGG03088.1 - 9.8 6.6 12.9 1.3 9.4 8.7 1.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 NAM-associated PF14303.6 EGG03090.1 - 6.9e-16 59.4 0.7 9.5e-16 59.0 0.7 1.2 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain KxDL PF10241.9 EGG03090.1 - 2.1 8.7 9.1 1.9 8.8 1.7 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein SGS PF05002.15 EGG03091.1 - 1.9e-32 111.2 5.9 3.9e-32 110.2 5.9 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EGG03091.1 - 2e-16 60.8 1.5 2.2e-16 60.7 0.1 1.8 2 0 0 2 2 2 1 CS domain Glyco_hydro_2_N PF02837.18 EGG03099.1 - 0.089 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Pkinase PF00069.25 EGG03102.1 - 3e-48 164.5 0.0 5.4e-46 157.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG03102.1 - 3.9e-27 95.1 0.0 8e-17 61.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGG03102.1 - 1.1e-12 47.9 0.0 1.7e-10 40.7 0.0 2.1 1 1 1 2 2 2 2 Kinase-like FTA2 PF13095.6 EGG03102.1 - 0.0056 16.3 0.1 0.13 11.8 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGG03102.1 - 0.068 12.8 1.0 0.34 10.5 0.1 2.1 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 EGG03102.1 - 0.082 12.3 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGG03102.1 - 0.12 11.1 0.0 0.25 10.1 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Cupin_8 PF13621.6 EGG03103.1 - 1.2e-28 100.6 0.1 2.2e-28 99.7 0.1 1.5 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGG03103.1 - 8.5e-05 22.2 0.1 0.00023 20.7 0.0 1.8 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 EGG03103.1 - 0.00029 21.3 0.9 0.029 14.8 0.0 3.3 3 1 0 4 4 4 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EGG03103.1 - 0.075 12.8 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Semialdhyde_dh PF01118.24 EGG03103.1 - 0.22 12.0 0.0 0.47 10.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TonB_N PF16031.5 EGG03104.1 - 0.00042 20.8 4.9 0.0008 19.9 4.9 1.5 1 0 0 1 1 1 1 TonB polyproline region Trypan_PARP PF05887.11 EGG03104.1 - 0.016 15.2 4.9 0.023 14.7 4.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Phage_connect_1 PF05135.13 EGG03104.1 - 0.067 13.7 3.0 0.095 13.2 3.0 1.3 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein BUD22 PF09073.10 EGG03104.1 - 0.1 11.9 16.1 0.12 11.7 16.1 1.0 1 0 0 1 1 1 0 BUD22 AvrM_N PF18247.1 EGG03105.1 - 0.097 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain MBOAT_2 PF13813.6 EGG03107.1 - 9.9e-13 48.2 1.1 2.3e-12 47.0 1.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Defensin_2 PF01097.18 EGG03112.1 - 0.086 12.8 0.4 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 Arthropod defensin CBM_14 PF01607.24 EGG03112.1 - 1.3 9.2 5.4 0.97 9.6 2.1 2.2 2 1 1 3 3 3 0 Chitin binding Peritrophin-A domain DUF4470 PF14737.6 EGG03113.1 - 4.2e-12 46.1 0.0 1.4e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 EGG03113.1 - 0.0067 16.1 0.1 0.02 14.6 0.0 1.8 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.17 EGG03113.1 - 0.029 14.5 0.3 0.92 9.8 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG03113.1 - 0.074 13.4 0.9 0.21 11.9 0.1 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF4470 PF14737.6 EGG03114.1 - 4e-12 46.2 0.0 8.5e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_12 PF13424.6 EGG03114.1 - 0.1 12.9 0.7 0.29 11.4 0.1 1.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGG03114.1 - 0.12 12.0 0.3 0.44 10.3 0.1 2.0 1 1 1 2 2 2 0 TPR repeat HMD PF03201.16 EGG03115.1 - 0.085 13.1 0.5 0.23 11.7 0.2 1.8 1 1 1 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF5408 PF17402.2 EGG03116.1 - 0.15 12.0 1.3 0.23 11.4 1.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5408) Rhabdo_glycop PF00974.18 EGG03116.1 - 0.21 10.0 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein PEMT PF04191.13 EGG03118.1 - 9.6e-31 106.3 1.7 1.6e-29 102.4 0.3 2.6 3 0 0 3 3 3 1 Phospholipid methyltransferase YTH PF04146.15 EGG03122.1 - 4e-39 134.2 0.3 7.2e-39 133.4 0.3 1.4 1 1 0 1 1 1 1 YT521-B-like domain GST_N_4 PF17172.4 EGG03122.1 - 0.14 12.9 0.0 0.28 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain HLH PF00010.26 EGG03123.1 - 1.5e-14 53.7 2.9 3.5e-14 52.5 2.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.18 EGG03123.1 - 0.0074 16.5 0.2 0.019 15.2 0.2 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper WD40 PF00400.32 EGG03124.1 - 1.6e-12 47.7 5.8 0.00034 21.3 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG03124.1 - 0.0012 19.2 0.0 0.0045 17.3 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain UDG PF03167.19 EGG03125.1 - 3.1e-09 37.0 0.0 6.2e-08 32.8 0.0 2.8 2 2 1 3 3 3 1 Uracil DNA glycosylase superfamily Cpn60_TCP1 PF00118.24 EGG03127.1 - 2.2e-146 488.3 12.3 2.7e-146 488.1 12.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PTPA PF03095.15 EGG03128.1 - 4.5e-121 403.9 0.1 5.3e-121 403.7 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF4064 PF13273.6 EGG03129.1 - 0.00041 20.6 8.8 0.0016 18.7 0.9 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4064) Ost5 PF05251.12 EGG03129.1 - 0.065 13.5 5.2 0.16 12.3 0.6 2.7 2 1 0 2 2 2 0 Oligosaccharyltransferase subunit 5 DUF3149 PF11346.8 EGG03129.1 - 0.26 10.9 5.4 3.2 7.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) Phage_holin_Dp1 PF16938.5 EGG03129.1 - 3.1 8.1 8.3 0.78 10.0 1.6 2.8 2 1 1 3 3 3 0 Putative phage holin Dp-1 DUF3328 PF11807.8 EGG03129.1 - 6.8 6.4 5.7 11 5.8 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) ATP-synt_Z PF16594.5 EGG03129.1 - 7 6.2 10.8 1.2 8.7 4.9 2.7 2 1 1 3 3 3 0 Putative AtpZ or ATP-synthase-associated TssN PF17555.2 EGG03129.1 - 7.7 5.8 13.9 2.2 7.6 5.6 2.0 1 1 1 2 2 2 0 Type VI secretion system, TssN CbtA PF09490.10 EGG03129.1 - 8.7 6.0 9.7 3.3 7.4 2.3 2.8 2 1 1 3 3 3 0 Probable cobalt transporter subunit (CbtA) Pkinase PF00069.25 EGG03132.1 - 6e-07 29.1 0.0 0.015 14.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain DUF4537 PF15057.6 EGG03133.1 - 2.1e-08 34.2 0.1 2.7e-05 24.2 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) PWWP PF00855.17 EGG03133.1 - 1.3e-06 28.7 2.0 0.0018 18.6 0.0 3.3 3 0 0 3 3 3 2 PWWP domain Pyr_redox_2 PF07992.14 EGG03134.1 - 1.2e-68 231.5 2.5 1.8e-68 231.0 2.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGG03134.1 - 1.9e-39 134.3 0.4 4.2e-39 133.2 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGG03134.1 - 3.5e-23 82.0 6.3 2e-19 69.9 0.7 3.8 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGG03134.1 - 9.7e-14 51.2 3.0 1.1e-11 44.5 0.2 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGG03134.1 - 8.4e-13 48.5 9.0 2e-11 43.9 0.0 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGG03134.1 - 1.9e-12 47.1 4.7 4.5e-09 36.0 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG03134.1 - 5e-09 36.3 4.9 0.00017 21.7 0.8 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGG03134.1 - 9.4e-08 31.5 13.7 1.2e-07 31.2 2.4 3.8 2 1 2 4 4 4 1 FAD binding domain Thi4 PF01946.17 EGG03134.1 - 4.4e-07 29.4 1.1 0.00015 21.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 EGG03134.1 - 5e-07 28.8 12.8 0.00022 20.1 1.1 4.0 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.24 EGG03134.1 - 3.9e-06 26.7 9.4 0.13 11.8 0.1 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EGG03134.1 - 5.6e-06 25.8 2.2 0.021 14.1 0.4 2.5 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 EGG03134.1 - 0.00011 21.5 0.5 0.57 9.3 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EGG03134.1 - 0.00027 20.3 9.5 0.012 14.9 1.0 3.0 2 1 0 2 2 2 2 FAD binding domain Mqo PF06039.15 EGG03134.1 - 0.0027 16.4 2.7 0.0065 15.1 0.2 2.2 1 1 1 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Bac_A_amyl_C PF18612.1 EGG03134.1 - 0.064 13.0 0.3 0.33 10.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial Alpha amylase C-terminal domain NAD_binding_7 PF13241.6 EGG03134.1 - 1 9.8 4.8 6.4 7.3 1.0 3.2 2 1 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EGG03134.1 - 2 8.2 4.4 1 9.2 0.2 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Raftlin PF15250.6 EGG03135.1 - 5.4 5.6 9.9 6.1 5.5 9.9 1.1 1 0 0 1 1 1 0 Raftlin Plasmodium_Vir PF05795.11 EGG03135.1 - 5.5 6.3 7.9 6.2 6.1 7.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDC45 PF02724.14 EGG03135.1 - 7.7 4.7 9.9 8.8 4.5 9.9 1.0 1 0 0 1 1 1 0 CDC45-like protein ZirS_C PF16583.5 EGG03137.1 - 0.0029 17.2 0.1 0.0055 16.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-regulated secreted antivirulence protein C-terminal domain Plant_NMP1 PF06694.11 EGG03137.1 - 0.033 13.3 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) NPV_P10 PF05531.12 EGG03137.1 - 0.074 13.5 0.2 0.27 11.7 0.2 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EGG03137.1 - 0.13 12.3 0.8 1.5 8.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YlbD_coat PF14071.6 EGG03137.1 - 0.38 11.0 1.1 2.6 8.3 0.8 2.1 1 1 1 2 2 2 0 Putative coat protein DUF1295 PF06966.12 EGG03138.1 - 1.3e-55 188.5 7.1 1.9e-55 188.0 7.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EGG03138.1 - 3.7e-05 23.8 0.1 3.7e-05 23.8 0.1 3.1 2 1 0 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EGG03138.1 - 6e-05 23.4 0.1 0.00059 20.2 0.1 2.5 1 1 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 EGG03138.1 - 0.0031 17.9 0.1 0.012 16.0 0.0 2.0 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family RGS12_us1 PF16613.5 EGG03139.1 - 0.11 12.9 0.4 2.8 8.3 0.1 2.5 2 1 0 3 3 3 0 Unstructured region of RGS12 Carn_acyltransf PF00755.20 EGG03140.1 - 2.8e-166 554.6 0.0 3.1e-166 554.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Prefoldin PF02996.17 EGG03141.1 - 4.5e-25 87.9 3.7 5.7e-25 87.6 3.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit BCAS3 PF12490.8 EGG03141.1 - 0.025 14.1 0.1 0.048 13.2 0.1 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Zn_clus PF00172.18 EGG03144.1 - 1.3e-07 31.6 11.2 2.3e-07 30.8 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGG03144.1 - 2.1e-06 27.0 0.3 2.1e-06 27.0 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3896 PF13035.6 EGG03144.1 - 0.086 13.0 1.2 0.18 12.0 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) Plasmid_RAQPRD PF09686.10 EGG03144.1 - 0.56 10.5 2.6 1.2 9.4 2.6 1.5 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) RmlD_sub_bind PF04321.17 EGG03146.1 - 9.4e-51 172.6 0.0 1.3e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGG03146.1 - 1.6e-23 83.4 0.0 2.4e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG03146.1 - 2.6e-10 40.3 0.0 3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGG03146.1 - 2.2e-06 27.1 0.0 2.6e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGG03146.1 - 0.0046 16.2 0.0 0.0077 15.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Cullin_binding PF03556.15 EGG03148.1 - 2e-33 115.3 3.2 2e-32 112.2 2.5 2.1 2 0 0 2 2 2 1 Cullin binding FANCI_S3 PF14677.6 EGG03148.1 - 0.082 12.6 0.7 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 FANCI solenoid 3 Terpene_synth PF01397.21 EGG03148.1 - 0.097 12.3 0.9 4.8 6.8 0.0 2.8 3 0 0 3 3 3 0 Terpene synthase, N-terminal domain PEMT PF04191.13 EGG03149.1 - 4.1e-53 178.3 10.3 6.9e-32 110.0 2.0 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 EGG03149.1 - 0.033 14.8 0.0 0.32 11.6 0.0 2.5 2 0 0 2 2 2 0 SKICH domain HECW_N PF16562.5 EGG03149.1 - 0.035 13.9 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 ApoO PF09769.9 EGG03149.1 - 0.074 13.0 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein O Flu_PB2 PF00604.17 EGG03149.1 - 0.2 9.5 0.0 0.29 9.0 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 DUF3987 PF13148.6 EGG03151.1 - 0.035 13.1 0.5 0.1 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) GCM PF03615.15 EGG03151.1 - 0.059 13.3 2.4 0.18 11.6 2.4 1.8 1 0 0 1 1 1 0 GCM motif protein OSCP PF00213.18 EGG03152.1 - 0.041 14.0 0.1 0.054 13.6 0.1 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit MFS_1 PF07690.16 EGG03153.1 - 1.8e-45 155.5 31.7 9.8e-40 136.6 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EGG03153.1 - 8.5e-06 24.4 5.4 8.5e-06 24.4 5.4 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_4 PF06779.14 EGG03153.1 - 0.0035 16.7 3.0 0.0035 16.7 3.0 2.6 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 EGG03153.1 - 0.064 12.1 19.3 0.13 11.0 0.1 3.6 2 2 1 3 3 3 0 Sugar (and other) transporter PUCC PF03209.15 EGG03153.1 - 0.065 12.2 9.0 0.071 12.1 3.5 2.8 2 2 0 2 2 2 0 PUCC protein LacY_symp PF01306.19 EGG03153.1 - 0.075 11.8 15.7 0.43 9.3 0.6 3.8 4 0 0 4 4 4 0 LacY proton/sugar symporter OATP PF03137.20 EGG03153.1 - 0.11 10.8 9.3 0.065 11.5 3.2 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EGG03153.1 - 0.34 9.7 18.8 4.1 6.2 7.6 3.5 2 2 1 3 3 3 0 MFS_1 like family ALO PF04030.14 EGG03154.1 - 3.3e-64 217.2 0.0 4.1e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EGG03154.1 - 4.8e-25 87.9 0.0 7.5e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lipoprotein_1 PF00820.19 EGG03154.1 - 0.069 12.2 0.0 0.42 9.6 0.0 2.0 2 0 0 2 2 2 0 Borrelia lipoprotein Mito_carr PF00153.27 EGG03155.1 - 1.4e-63 210.8 0.6 6.8e-24 83.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGG03155.1 - 0.058 12.6 0.1 8.4 5.5 0.0 3.4 3 1 1 4 4 4 0 Gammaproteobacterial serine protease GFO_IDH_MocA PF01408.22 EGG03158.1 - 8.8e-16 58.8 0.0 1.5e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Myb_DNA-bind_3 PF12776.7 EGG03159.1 - 9.2e-05 23.4 0.3 0.0002 22.3 0.3 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain F-box-like PF12937.7 EGG03162.1 - 0.0069 16.3 0.6 0.019 14.8 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGG03162.1 - 0.49 10.3 5.4 0.44 10.5 1.6 2.6 2 0 0 2 2 2 0 F-box domain Gtr1_RagA PF04670.12 EGG03163.1 - 2.1e-64 217.1 0.0 2.6e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF4646 PF15496.6 EGG03165.1 - 0.05 14.2 0.0 0.14 12.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) FAD_binding_3 PF01494.19 EGG03165.1 - 0.25 10.6 0.0 0.35 10.1 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Vps35 PF03635.17 EGG03167.1 - 0 1017.8 2.4 0 1017.6 2.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF758 PF05527.11 EGG03167.1 - 0.2 11.7 2.4 0.57 10.2 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF758) Cupin_8 PF13621.6 EGG03173.1 - 3.1e-14 53.3 0.0 8.6e-13 48.6 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EGG03173.1 - 2.5e-11 44.0 0.2 2.8e-10 40.6 0.2 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box PF00646.33 EGG03173.1 - 0.00056 19.7 1.0 0.0013 18.6 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGG03173.1 - 0.00069 19.5 0.0 0.0022 17.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.12 EGG03173.1 - 0.004 16.7 0.0 0.0059 16.1 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 EGG03173.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 EGG03173.1 - 0.095 12.4 0.0 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 Cupin domain Gp-FAR-1 PF05823.12 EGG03173.1 - 0.11 12.9 0.4 0.2 12.0 0.4 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Gaa1 PF04114.14 EGG03174.1 - 1e-90 305.2 0.0 1.2e-78 265.3 0.0 2.6 2 1 1 3 3 3 2 Gaa1-like, GPI transamidase component DUF2721 PF11026.8 EGG03174.1 - 0.4 10.6 3.9 2.2 8.2 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF2417 PF10329.9 EGG03174.1 - 0.98 8.8 6.1 0.44 9.9 0.2 2.3 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF3381 PF11861.8 EGG03174.1 - 7.2 6.4 11.7 0.42 10.4 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) LRR_8 PF13855.6 EGG03175.1 - 0.0069 16.1 0.0 8.1 6.3 0.0 4.3 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 EGG03175.1 - 0.008 16.6 0.4 1.1 9.7 0.0 3.7 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Nodulin PF02451.15 EGG03176.1 - 0.02 14.4 0.0 0.49 9.8 0.0 2.6 2 0 0 2 2 2 0 Nodulin Ribosomal_L21e PF01157.18 EGG03177.1 - 1.2e-44 150.3 4.7 1.5e-44 149.9 4.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e DHHA2 PF02833.14 EGG03178.1 - 1.1e-13 51.5 0.0 3.1e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 EGG03178.1 - 2.8e-08 33.9 0.0 4.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 DHH family OrsD PF12013.8 EGG03178.1 - 0.19 12.2 0.1 0.45 11.0 0.1 1.5 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF89 PF01937.19 EGG03179.1 - 3.6e-111 371.5 0.1 4.2e-111 371.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 NST1 PF13945.6 EGG03180.1 - 5e-44 150.7 0.4 5e-44 150.7 0.4 6.6 5 3 2 7 7 7 2 Salt tolerance down-regulator PfkB PF00294.24 EGG03182.1 - 3.4e-15 56.1 0.0 5.3e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EGG03182.1 - 0.00034 20.1 0.0 0.00049 19.6 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Polyketide_cyc PF03364.20 EGG03183.1 - 2.8e-18 66.4 0.0 3.9e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EGG03184.1 - 6.3e-17 62.0 0.0 9.9e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ysc84 PF04366.12 EGG03185.1 - 1.7e-24 86.0 0.0 7.5e-22 77.5 0.0 2.4 2 0 0 2 2 2 2 Las17-binding protein actin regulator SPP PF06550.11 EGG03185.1 - 0.11 12.0 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease FYVE PF01363.21 EGG03189.1 - 1.8e-19 69.6 0.0 4.7e-19 68.3 0.0 1.7 1 1 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 EGG03189.1 - 6.8e-10 38.5 2.9 6.8e-10 38.5 2.9 2.3 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-C4_ClpX PF06689.13 EGG03189.1 - 0.31 11.0 0.0 0.31 11.0 0.0 2.4 3 0 0 3 3 3 0 ClpX C4-type zinc finger PDCD2_C PF04194.13 EGG03191.1 - 3e-38 131.6 1.6 1.1e-34 120.1 0.5 3.0 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain UCH PF00443.29 EGG03191.1 - 9.7e-05 22.0 0.0 0.00048 19.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 EGG03191.1 - 0.013 15.4 6.2 1.4 9.0 0.0 3.5 2 0 0 2 2 2 0 Ubiquitin interaction motif HCV_NS5a_C PF12941.7 EGG03191.1 - 6.3 6.6 8.7 0.12 12.2 0.2 2.0 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region Mid1 PF12929.7 EGG03192.1 - 5.6e-69 233.4 2.6 1.1e-68 232.4 2.6 1.4 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EGG03192.1 - 0.058 14.0 3.8 1.4 9.5 0.5 2.6 2 0 0 2 2 2 0 Fz domain zf-CCHC_4 PF14392.6 EGG03193.1 - 0.02 14.6 0.8 0.032 14.0 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle Coq4 PF05019.13 EGG03196.1 - 4.2e-96 320.6 0.0 5.2e-96 320.3 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 HEAT PF02985.22 EGG03197.1 - 1.2e-20 71.8 5.3 0.00066 19.7 0.0 11.0 12 0 0 12 12 11 3 HEAT repeat HEAT_EZ PF13513.6 EGG03197.1 - 1.2e-18 67.2 4.5 7.3e-12 45.5 0.0 7.5 7 0 0 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 EGG03197.1 - 6e-13 49.0 11.2 0.092 13.1 0.0 7.6 4 3 2 6 6 6 4 HEAT repeats IBN_N PF03810.19 EGG03197.1 - 1.5e-09 37.6 3.9 4.4e-07 29.7 0.2 4.3 3 1 1 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.23 EGG03197.1 - 2.7e-08 33.6 6.5 0.0076 16.3 0.0 6.1 6 0 0 6 6 5 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGG03197.1 - 4e-05 23.7 0.0 0.16 12.0 0.0 3.3 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 EGG03197.1 - 9.8e-05 21.6 2.2 0.3 10.1 0.2 4.1 3 1 0 3 3 3 2 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 EGG03197.1 - 0.0054 16.3 0.0 26 4.3 0.0 4.1 4 1 1 5 5 5 0 CLASP N terminal MMS19_C PF12460.8 EGG03197.1 - 0.012 14.8 0.9 0.68 9.0 0.0 3.1 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 EGG03197.1 - 0.06 13.2 0.2 7.8 6.4 0.0 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Spexin PF15171.6 EGG03197.1 - 0.08 13.2 0.4 0.31 11.3 0.2 2.1 2 0 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin TIP120 PF08623.10 EGG03197.1 - 0.16 11.7 0.0 3.4 7.4 0.0 3.1 3 2 2 5 5 5 0 TATA-binding protein interacting (TIP20) DRIM PF07539.12 EGG03197.1 - 0.29 9.4 3.0 9.4 4.4 0.0 3.9 3 2 1 4 4 4 0 Down-regulated in metastasis Abhydrolase_6 PF12697.7 EGG03198.1 - 0.0018 18.9 1.6 0.0067 17.1 1.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Staufen_C PF16482.5 EGG03198.1 - 0.15 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Staufen C-terminal domain SNF2_N PF00176.23 EGG03201.1 - 6.6e-32 110.6 0.0 4.3e-22 78.3 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG03201.1 - 1.6e-18 67.0 0.0 4.4e-16 59.2 0.0 2.9 2 1 1 3 3 3 2 Helicase conserved C-terminal domain UQ_con PF00179.26 EGG03203.1 - 1.7e-44 150.8 0.0 2e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGG03203.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B 60KD_IMP PF02096.20 EGG03204.1 - 3e-19 69.5 0.4 4.5e-19 69.0 0.4 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3070 PF11270.8 EGG03204.1 - 0.013 15.7 1.6 0.042 14.1 1.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3070) DUF5398 PF17376.2 EGG03204.1 - 0.059 14.0 1.0 0.11 13.2 1.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5398) CBS PF00571.28 EGG03205.1 - 5.2e-06 26.8 2.5 1.8 9.1 0.0 4.4 1 1 3 4 4 4 4 CBS domain Ribonuclease_3 PF00636.26 EGG03206.1 - 0.00094 19.8 0.0 0.015 15.9 0.0 2.8 1 1 0 1 1 1 1 Ribonuclease III domain DUF1247 PF06851.11 EGG03206.1 - 0.11 12.4 0.1 0.34 10.9 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1247) FAD_binding_1 PF00667.20 EGG03207.1 - 7.3e-43 146.7 0.0 1.3e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGG03207.1 - 1e-25 90.6 0.0 1.9e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGG03207.1 - 3.4e-14 53.4 0.0 7.2e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain T6SS_VipA PF05591.12 EGG03207.1 - 0.089 12.6 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 SeqA_N PF17206.3 EGG03207.1 - 2.4 7.5 6.9 2.2 7.7 0.1 3.1 3 0 0 3 3 3 0 SeqA protein N-terminal domain Glyco_hydro_32N PF00251.20 EGG03208.1 - 2.6e-29 102.7 3.5 4e-22 79.2 2.8 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EGG03208.1 - 1.5e-21 77.1 0.2 3.1e-21 76.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 EGG03208.1 - 0.047 13.8 0.1 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4975) ASD2 PF08687.11 EGG03209.1 - 0.18 11.3 7.1 0.2 11.2 7.1 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 PPP4R2 PF09184.11 EGG03209.1 - 0.33 10.5 15.2 0.39 10.2 15.2 1.1 1 0 0 1 1 1 0 PPP4R2 DUF5094 PF17015.5 EGG03209.1 - 0.99 9.5 8.3 1.4 9.0 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Sec62 PF03839.16 EGG03209.1 - 4.9 6.6 8.8 5.9 6.3 8.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 NOA36 PF06524.12 EGG03209.1 - 9.6 5.4 10.5 12 5.1 10.5 1.1 1 0 0 1 1 1 0 NOA36 protein Nup192 PF11894.8 EGG03210.1 - 0.0034 14.6 0.1 0.004 14.4 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 zf-RING_5 PF14634.6 EGG03212.1 - 7.4e-05 22.6 11.8 0.00017 21.4 11.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG03212.1 - 0.00053 20.0 12.4 0.00099 19.1 12.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger AIP3 PF03915.13 EGG03212.1 - 0.0011 18.1 6.7 0.0017 17.5 6.7 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Baculo_IE-1 PF05290.11 EGG03212.1 - 0.0023 17.9 3.6 0.0023 17.9 3.6 1.7 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Spc7 PF08317.11 EGG03212.1 - 0.0026 16.7 7.9 0.0034 16.3 7.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein JIP_LZII PF16471.5 EGG03212.1 - 0.0053 16.9 8.8 0.19 11.9 0.5 2.6 2 1 0 2 2 2 2 JNK-interacting protein leucine zipper II zf-RING_2 PF13639.6 EGG03212.1 - 0.0069 16.7 11.7 0.013 15.8 11.2 1.8 1 1 0 1 1 1 1 Ring finger domain CENP-K PF11802.8 EGG03212.1 - 0.037 13.6 7.2 0.05 13.2 7.2 1.1 1 0 0 1 1 1 0 Centromere-associated protein K KASH_CCD PF14662.6 EGG03212.1 - 0.043 13.6 11.4 0.1 12.4 11.3 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH zf-C3HC4 PF00097.25 EGG03212.1 - 0.052 13.4 11.6 0.13 12.2 11.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGG03212.1 - 0.12 12.6 10.0 0.65 10.2 10.1 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING bZIP_1 PF00170.21 EGG03212.1 - 0.14 12.3 8.4 0.38 10.9 2.1 3.0 2 1 1 3 3 3 0 bZIP transcription factor FUSC PF04632.12 EGG03212.1 - 0.15 10.6 0.1 0.18 10.3 0.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family FYVE PF01363.21 EGG03212.1 - 0.18 12.0 7.8 0.11 12.6 5.7 1.7 2 0 0 2 2 1 0 FYVE zinc finger ATG16 PF08614.11 EGG03212.1 - 0.2 11.9 7.7 0.53 10.5 7.7 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 EGG03212.1 - 0.21 11.9 8.5 0.79 10.1 4.5 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C3HC4_2 PF13923.6 EGG03212.1 - 0.26 11.2 9.8 0.93 9.4 9.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HlyD_2 PF12700.7 EGG03212.1 - 0.34 9.6 8.8 1.4 7.6 8.8 1.7 1 1 0 1 1 1 0 HlyD family secretion protein Prok-RING_4 PF14447.6 EGG03212.1 - 0.37 10.7 7.7 0.44 10.4 6.3 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 HALZ PF02183.18 EGG03212.1 - 0.4 10.9 3.3 4 7.7 1.2 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper TSC22 PF01166.18 EGG03212.1 - 1.1 9.6 8.4 0.7 10.2 2.0 2.9 1 1 2 3 3 3 0 TSC-22/dip/bun family CtIP_N PF10482.9 EGG03212.1 - 1.2 9.2 8.5 0.64 10.1 3.3 2.6 1 1 2 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain MbeD_MobD PF04899.12 EGG03212.1 - 1.4 9.0 4.6 6.2 7.0 1.7 2.3 1 1 1 2 2 2 0 MbeD/MobD like Spectrin PF00435.21 EGG03212.1 - 1.5 9.3 7.6 1.8 9.1 5.9 1.8 1 1 1 2 2 2 0 Spectrin repeat DivIC PF04977.15 EGG03212.1 - 2.4 8.0 11.6 4.3 7.2 5.2 2.8 1 1 1 2 2 2 0 Septum formation initiator Baculo_PEP_C PF04513.12 EGG03212.1 - 2.5 8.1 13.1 10 6.2 9.9 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Csm1_N PF18504.1 EGG03212.1 - 5 7.5 9.3 0.73 10.2 3.2 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain Kazal_2 PF07648.15 EGG03215.1 - 0.0073 16.4 0.5 0.016 15.3 0.5 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Ima1_N PF09779.9 EGG03215.1 - 3.8 8.4 10.0 25 5.7 10.0 2.0 1 1 0 1 1 1 0 Ima1 N-terminal domain GCP_C_terminal PF04130.13 EGG03217.1 - 3.2e-09 36.7 0.0 4.2e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Baculo_11_kDa PF06143.11 EGG03218.1 - 0.036 13.6 0.7 0.036 13.6 0.7 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family Neur_chan_memb PF02932.16 EGG03218.1 - 0.34 10.9 0.1 0.34 10.9 0.1 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RCR PF12273.8 EGG03218.1 - 3.2 8.4 4.8 23 5.7 0.3 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Acid_PPase PF12689.7 EGG03221.1 - 4.9e-57 192.5 0.0 5.6e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase DcuC PF03606.15 EGG03222.1 - 0.00086 17.9 5.0 0.00086 17.9 5.0 1.4 2 0 0 2 2 2 1 C4-dicarboxylate anaerobic carrier DUF4064 PF13273.6 EGG03222.1 - 0.05 13.9 11.3 0.98 9.7 0.0 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Nodulin_late PF07127.11 EGG03222.1 - 0.27 11.6 3.0 2.7 8.4 0.4 2.9 2 0 0 2 2 2 0 Late nodulin protein Mito_carr PF00153.27 EGG03223.1 - 5e-46 154.6 0.1 7.8e-15 54.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Rer1 PF03248.13 EGG03224.1 - 0.029 14.1 0.1 9.4 5.9 0.0 2.9 1 1 2 3 3 3 0 Rer1 family DUF3463 PF11946.8 EGG03224.1 - 0.091 12.6 0.1 48 3.7 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3463) VPS53_C PF16854.5 EGG03225.1 - 0.012 15.5 0.2 0.024 14.5 0.0 1.5 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus DUF1687 PF07955.11 EGG03225.1 - 0.032 14.7 0.0 0.082 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) LRR_4 PF12799.7 EGG03225.1 - 0.38 11.2 9.1 14 6.2 4.2 4.7 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) ADH_zinc_N PF00107.26 EGG03227.1 - 2.5e-23 82.5 0.2 5e-23 81.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG03227.1 - 1.5e-05 24.8 0.0 6.4e-05 22.8 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGG03227.1 - 4.6e-05 24.5 0.0 8.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGG03227.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Acyl_transf_3 PF01757.22 EGG03229.1 - 2.4e-28 99.2 21.9 4.6e-28 98.2 21.9 1.5 1 1 0 1 1 1 1 Acyltransferase family p31comet PF06581.12 EGG03229.1 - 0.069 12.3 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding DUF1335 PF07056.11 EGG03230.1 - 0.03 14.4 0.1 0.035 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) HlyIII PF03006.20 EGG03231.1 - 3.8e-55 187.1 17.0 4.8e-55 186.7 17.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related Multi_Drug_Res PF00893.19 EGG03231.1 - 0.013 16.1 0.6 0.041 14.6 0.2 2.2 2 1 0 2 2 2 0 Small Multidrug Resistance protein Glyco_hydro_63 PF03200.16 EGG03232.1 - 3.6e-08 32.6 5.4 2.8e-05 23.1 0.4 4.4 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain Mucin PF01456.17 EGG03233.1 - 0.011 15.8 22.3 0.025 14.6 22.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein AJAP1_PANP_C PF15298.6 EGG03233.1 - 0.03 14.6 10.2 0.042 14.1 10.2 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus TMEM154 PF15102.6 EGG03233.1 - 0.73 9.7 7.7 1.1 9.1 7.7 1.3 1 0 0 1 1 1 0 TMEM154 protein family UQ_con PF00179.26 EGG03235.1 - 0.025 14.2 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme tify PF06200.14 EGG03236.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 tify domain GSG-1 PF07803.11 EGG03237.1 - 0.24 11.3 5.8 0.57 10.1 5.8 1.7 1 1 0 1 1 1 0 GSG1-like protein zf-C2H2_10 PF16588.5 EGG03238.1 - 1.2 9.0 5.3 0.25 11.1 1.2 2.1 2 0 0 2 2 2 0 C2H2 zinc-finger DUF1769 PF08588.10 EGG03239.1 - 8.6e-15 54.7 0.1 2e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) PNGaseA PF12222.8 EGG03240.1 - 6.2e-101 338.4 0.1 1.1e-100 337.6 0.1 1.3 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A N-glycanase_N PF09112.10 EGG03240.1 - 0.057 13.2 0.0 4.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Peptide-N-glycosidase F, N terminal MS_channel PF00924.18 EGG03241.1 - 4.7e-11 42.6 5.1 6.2e-11 42.2 3.1 2.1 1 1 1 2 2 2 1 Mechanosensitive ion channel RPN6_N PF18055.1 EGG03241.1 - 0.056 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain SRTM1 PF15872.5 EGG03241.1 - 0.14 12.3 0.4 2.4 8.3 0.1 2.3 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 XRCC4 PF06632.12 EGG03242.1 - 5 5.9 12.7 5.4 5.8 12.7 1.3 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF2681 PF10883.8 EGG03242.1 - 8.6 6.8 7.7 17 5.9 6.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Golgin_A5 PF09787.9 EGG03244.1 - 0.64 9.4 14.0 1.3 8.4 14.0 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 PRKG1_interact PF15898.5 EGG03244.1 - 3.4 8.6 14.0 13 6.7 14.0 2.0 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain CCDC-167 PF15188.6 EGG03244.1 - 3.5 8.0 15.5 20 5.6 15.5 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 FapA PF03961.13 EGG03244.1 - 7 5.1 7.1 11 4.5 7.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A P_proprotein PF01483.20 EGG03245.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Proprotein convertase P-domain PRIMA1 PF16101.5 EGG03245.1 - 0.13 12.3 2.1 0.29 11.2 2.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Senescence PF06911.12 EGG03248.1 - 0.48 10.7 3.1 1.2 9.4 1.3 2.1 2 0 0 2 2 2 0 Senescence-associated protein Apolipoprotein PF01442.18 EGG03250.1 - 0.0001 22.2 0.5 0.00022 21.2 0.1 1.6 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EGG03250.1 - 0.00071 19.6 2.7 0.0022 18.0 2.7 1.8 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 EGG03250.1 - 0.0081 15.5 2.6 0.0081 15.5 2.6 1.5 2 0 0 2 2 2 1 SF-assemblin/beta giardin DUF1664 PF07889.12 EGG03250.1 - 0.0091 16.0 2.1 0.02 14.9 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) RmuC PF02646.16 EGG03250.1 - 0.034 13.3 0.5 0.067 12.3 0.5 1.4 1 0 0 1 1 1 0 RmuC family Senescence PF06911.12 EGG03250.1 - 0.035 14.4 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 Senescence-associated protein DUF1640 PF07798.11 EGG03250.1 - 0.04 14.0 2.1 0.074 13.1 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) COG2 PF06148.11 EGG03250.1 - 0.057 13.5 0.7 0.11 12.5 0.7 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Lipoprotein_7 PF01540.16 EGG03250.1 - 0.14 11.5 0.9 0.38 10.0 0.7 1.7 2 0 0 2 2 2 0 Adhesin lipoprotein Fzo_mitofusin PF04799.13 EGG03250.1 - 0.29 10.7 1.1 0.64 9.6 1.1 1.5 1 0 0 1 1 1 0 fzo-like conserved region Homeodomain PF00046.29 EGG03251.1 - 3.4e-12 46.0 0.7 5.1e-12 45.4 0.7 1.3 1 0 0 1 1 1 1 Homeodomain Shigella_OspC PF06128.11 EGG03251.1 - 0.094 12.4 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Shigella flexneri OspC protein Homez PF11569.8 EGG03251.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Oxidored_q6 PF01058.22 EGG03252.1 - 8.8e-22 77.3 0.1 1.4e-21 76.7 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Nup_retrotrp_bd PF10599.9 EGG03252.1 - 0.032 14.9 0.9 0.057 14.1 0.9 1.6 1 0 0 1 1 1 0 Retro-transposon transporting motif Retrotran_gag_2 PF14223.6 EGG03253.1 - 6e-10 38.9 0.7 1.1e-09 38.0 0.7 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MIP-T3 PF10243.9 EGG03253.1 - 0.071 13.1 0.1 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CH-like domain Det1 PF09737.9 EGG03256.1 - 0.02 13.9 1.4 0.021 13.9 1.4 1.0 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 AA_permease PF00324.21 EGG03258.1 - 4.6e-100 335.5 37.1 5.6e-100 335.2 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGG03258.1 - 3.5e-27 95.3 38.6 5.1e-27 94.8 38.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGG03259.1 - 2.3e-69 234.3 34.4 8.1e-53 179.7 23.2 4.0 1 1 2 3 3 3 3 Amino acid permease AA_permease_2 PF13520.6 EGG03259.1 - 1.2e-13 50.7 30.0 1.6e-11 43.7 29.7 3.4 1 1 0 1 1 1 1 Amino acid permease WTF PF03303.13 EGG03259.1 - 0.12 12.1 4.2 0.2 11.3 4.2 1.3 1 0 0 1 1 1 0 WTF protein Pinin_SDK_memA PF04696.13 EGG03263.1 - 6.8e-18 65.0 10.1 6.8e-18 65.0 10.1 3.5 2 1 1 3 3 3 2 pinin/SDK/memA/ protein conserved region FA_desaturase PF00487.24 EGG03265.1 - 2.3e-21 76.8 29.2 4.3e-21 75.9 29.2 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EGG03265.1 - 7e-07 29.5 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) OATP PF03137.20 EGG03265.1 - 0.0013 17.1 0.1 0.0016 16.8 0.1 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family SLS PF14611.6 EGG03266.1 - 4.8e-06 26.6 0.0 0.00023 21.1 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial inner-membrane-bound regulator DUF2247 PF10004.9 EGG03267.1 - 0.025 14.3 0.2 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) GST_N PF02798.20 EGG03268.1 - 1.4e-22 79.8 0.2 6.5e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGG03268.1 - 4.4e-13 49.4 0.0 7.7e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGG03268.1 - 1.5e-12 47.7 0.0 4.9e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG03268.1 - 2.3e-12 47.0 0.0 4.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG03268.1 - 1.1e-11 44.8 0.0 2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG03268.1 - 0.00026 20.9 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain adh_short_C2 PF13561.6 EGG03271.1 - 0.015 14.9 0.0 0.015 14.8 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RNase_PH_C PF03725.15 EGG03271.1 - 0.098 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 CENP-S PF15630.6 EGG03272.1 - 1.6e-29 102.1 0.5 2.3e-29 101.6 0.5 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGG03272.1 - 1.3e-05 25.3 0.1 1.6e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold P22_portal PF16510.5 EGG03272.1 - 0.0064 15.2 2.4 0.0079 14.9 2.4 1.0 1 0 0 1 1 1 1 Phage P22-like portal protein Bromo_TP PF07524.13 EGG03272.1 - 0.0067 16.4 0.1 0.0096 15.9 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EGG03272.1 - 0.011 15.8 1.1 0.02 15.0 0.5 1.7 1 1 1 2 2 2 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EGG03272.1 - 5 7.5 7.8 0.79 10.1 2.8 2.4 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CHD5 PF04420.14 EGG03273.1 - 2.2e-55 186.9 2.4 2.6e-55 186.6 2.4 1.0 1 0 0 1 1 1 1 CHD5-like protein Melittin PF01372.17 EGG03273.1 - 0.092 12.7 0.4 3.8 7.7 0.0 2.7 2 0 0 2 2 2 0 Melittin TIG PF01833.24 EGG03274.1 - 1.5e-10 41.0 0.0 1.2e-09 38.2 0.0 2.7 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.7 EGG03274.1 - 6.9e-06 26.6 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGG03274.1 - 0.00016 21.9 0.0 0.012 16.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGG03274.1 - 0.00072 20.1 0.0 0.18 12.4 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG03274.1 - 0.026 14.8 0.0 0.69 10.3 0.0 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) G-alpha PF00503.20 EGG03275.1 - 2.2e-105 352.8 0.1 2.5e-105 352.5 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGG03275.1 - 1.8e-15 56.8 1.1 1.6e-10 40.7 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG03275.1 - 0.00032 20.1 4.6 0.002 17.5 0.0 2.4 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EGG03275.1 - 0.0029 17.8 0.6 0.85 9.8 0.0 2.7 3 1 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 EGG03275.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGG03275.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EGG03275.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 EGG03275.1 - 0.087 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain CPT PF07931.12 EGG03275.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein FtsK_SpoIIIE PF01580.18 EGG03275.1 - 0.13 11.6 0.1 0.77 9.1 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family Mg_trans_NIPA PF05653.14 EGG03277.1 - 9.8e-14 51.1 9.4 8e-07 28.4 1.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EGG03277.1 - 7.3e-07 29.4 4.7 7.3e-07 29.4 4.7 3.7 4 0 0 4 4 4 2 EamA-like transporter family Phasin_2 PF09361.10 EGG03279.1 - 6.8e-05 23.1 0.0 0.5 10.6 0.0 2.4 2 1 0 2 2 2 2 Phasin protein Rap1_C PF11626.8 EGG03280.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Methyltransf_25 PF13649.6 EGG03281.1 - 2.6e-13 50.5 0.0 7.4e-13 49.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG03281.1 - 8.1e-13 48.4 0.1 1.6e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGG03281.1 - 1.3e-10 41.2 0.0 1.9e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGG03281.1 - 1.8e-10 41.3 0.0 4.5e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG03281.1 - 1.5e-08 34.7 0.0 8.2e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EGG03281.1 - 1.6e-07 30.9 0.1 3e-07 30.0 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EGG03281.1 - 4.4e-07 29.1 0.1 6.6e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 EGG03281.1 - 1.2e-05 26.0 0.0 2.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG03281.1 - 1.4e-05 24.7 0.1 2.6e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EGG03281.1 - 0.00015 21.7 0.3 0.00025 21.0 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGG03281.1 - 0.0024 17.7 0.1 0.0036 17.1 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PRMT5 PF05185.16 EGG03281.1 - 0.0039 17.1 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 EGG03281.1 - 0.0047 16.7 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 EGG03281.1 - 0.0095 16.9 0.0 0.019 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGG03281.1 - 0.017 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 EGG03281.1 - 0.029 14.0 0.0 0.061 12.9 0.0 1.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EGG03281.1 - 0.043 13.6 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein FtsJ PF01728.19 EGG03281.1 - 0.056 13.6 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EGG03281.1 - 0.1 12.1 0.1 0.23 10.9 0.1 1.6 2 0 0 2 2 2 0 Putative methyltransferase Cons_hypoth95 PF03602.15 EGG03281.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CBM9_2 PF16011.5 EGG03282.1 - 0.00035 20.3 0.1 0.00058 19.6 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate-binding family 9 GNAT_acetyltr_2 PF13718.6 EGG03283.1 - 1.1e-92 309.5 0.0 1.1e-92 309.5 0.0 3.0 4 0 0 4 4 4 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EGG03283.1 - 3.6e-81 272.3 4.2 3.6e-81 272.3 4.2 2.1 1 1 1 2 2 2 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EGG03283.1 - 4.9e-61 205.6 0.0 1.1e-60 204.5 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 EGG03283.1 - 2.9e-32 110.5 0.3 1.3e-31 108.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) Acetyltransf_7 PF13508.7 EGG03283.1 - 0.0062 16.9 0.0 0.054 13.9 0.0 2.6 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG03283.1 - 0.06 13.6 0.0 0.24 11.6 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Vhr1 PF04001.13 EGG03283.1 - 1.9 8.9 5.8 0.65 10.3 2.2 2.1 2 0 0 2 2 2 0 Transcription factor Vhr1 E1-E2_ATPase PF00122.20 EGG03284.1 - 6.5e-30 104.0 0.3 1.4e-29 102.9 0.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 EGG03284.1 - 1.6e-21 76.7 0.0 6.7e-21 74.7 0.0 2.1 1 1 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 EGG03284.1 - 3.6e-13 50.3 0.0 5.3e-06 26.9 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EGG03284.1 - 1.5e-05 24.7 2.5 3.7e-05 23.5 2.5 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGG03284.1 - 1.8e-05 24.7 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGG03284.1 - 0.0031 17.1 0.0 0.0074 15.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Glyco_hydro_61 PF03443.14 EGG03285.1 - 1.1e-25 90.8 0.3 2.8e-25 89.5 0.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CFEM PF05730.11 EGG03285.1 - 5.7e-09 36.0 11.2 5.7e-09 36.0 11.2 2.0 3 0 0 3 3 3 1 CFEM domain CBM_48 PF02922.18 EGG03285.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Big_3_4 PF13754.6 EGG03285.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Velvet PF11754.8 EGG03285.1 - 2 8.3 11.5 0.74 9.7 0.1 2.5 2 1 0 2 2 2 0 Velvet factor DUF5362 PF17319.2 EGG03288.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5362) Ndc1_Nup PF09531.10 EGG03289.1 - 0.91 8.1 6.1 1.3 7.6 6.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CytochromB561_N PF09786.9 EGG03289.1 - 4.7 6.1 10.6 8.4 5.3 10.6 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF3391 PF11871.8 EGG03290.1 - 0.011 16.3 4.2 0.016 15.8 4.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) SIR4_SID PF16991.5 EGG03290.1 - 0.022 14.8 1.6 0.027 14.5 1.6 1.1 1 0 0 1 1 1 0 Sir4 SID domain TFIIF_alpha PF05793.12 EGG03290.1 - 0.31 9.6 15.8 0.38 9.3 15.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ORC2 PF04084.14 EGG03291.1 - 2.7e-69 233.6 0.0 3.3e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Fasciclin PF02469.22 EGG03292.1 - 1e-49 168.0 0.0 9.9e-12 45.2 0.0 5.6 5 1 0 5 5 5 5 Fasciclin domain Cadherin_4 PF17803.1 EGG03292.1 - 0.083 13.5 0.4 0.32 11.7 0.4 2.0 1 0 0 1 1 1 0 Bacterial cadherin-like domain TPR_21 PF09976.9 EGG03292.1 - 0.72 9.5 1.9 1.1 8.9 1.9 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Cation_efflux PF01545.21 EGG03294.1 - 5.5e-46 156.8 17.1 9.3e-46 156.1 17.1 1.4 1 1 0 1 1 1 1 Cation efflux family Macoilin PF09726.9 EGG03294.1 - 0.09 11.3 2.9 0.12 10.9 2.9 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 EGG03294.1 - 9.8 5.3 19.2 28 3.8 19.1 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter Glyco_transf_49 PF13896.6 EGG03295.1 - 3e-15 56.4 0.0 5.8e-07 29.2 0.0 3.1 2 1 0 2 2 2 2 Glycosyl-transferase for dystroglycan Aminotran_1_2 PF00155.21 EGG03296.1 - 4.8e-59 200.4 0.0 5.4e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4911 PF16256.5 EGG03296.1 - 0.11 12.5 0.1 24 5.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) DUF4780 PF16012.5 EGG03297.1 - 0.067 12.7 0.3 0.094 12.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) Metallophos PF00149.28 EGG03304.1 - 5e-24 85.9 0.0 8.8e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EGG03304.1 - 9e-24 83.6 0.0 2e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 EGG03304.1 - 2.1e-06 27.3 0.0 7.7e-05 22.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGG03304.1 - 0.0013 18.3 0.1 0.18 11.5 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 EGG03304.1 - 0.03 14.7 0.0 2.7 8.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGG03304.1 - 0.044 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Cu-oxidase PF00394.22 EGG03305.1 - 1.2e-22 80.7 0.0 4.8e-21 75.5 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGG03305.1 - 1.1e-20 73.8 0.1 1.6e-19 70.1 0.1 2.5 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG03305.1 - 1.2e-15 57.4 2.4 4.3e-11 42.7 0.2 4.3 2 2 0 3 3 3 2 Multicopper oxidase Fe_hyd_lg_C PF02906.14 EGG03307.1 - 1.8e-54 185.0 0.0 2.8e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain OB_NTP_bind PF07717.16 EGG03307.1 - 0.11 12.9 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold ANAPC10 PF03256.16 EGG03308.1 - 4.8e-49 166.5 0.0 6.8e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Zn_clus PF00172.18 EGG03310.1 - 7e-08 32.5 13.7 1.3e-07 31.6 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ASFV_J13L PF05568.11 EGG03313.1 - 0.13 12.1 1.4 2 8.1 0.6 2.3 2 0 0 2 2 2 0 African swine fever virus J13L protein PI3_PI4_kinase PF00454.27 EGG03315.1 - 2e-43 149.0 0.1 2.8e-43 148.5 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EGG03315.1 - 3.9e-16 58.6 0.9 4.6e-15 55.1 0.3 2.3 2 0 0 2 2 2 1 FATC domain DUF4674 PF15719.5 EGG03316.1 - 0.03 14.4 0.2 0.035 14.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) SET PF00856.28 EGG03319.1 - 0.014 15.8 0.4 0.063 13.7 0.0 2.1 1 1 1 2 2 2 0 SET domain Cobl PF09469.10 EGG03319.1 - 7.1 7.0 7.3 8.5 6.7 0.7 3.3 4 0 0 4 4 4 0 Cordon-bleu ubiquitin-like domain CHCH PF06747.13 EGG03320.1 - 4.3e-06 26.7 5.1 9.1e-06 25.7 5.1 1.6 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EGG03320.1 - 0.012 16.0 2.4 0.024 15.1 2.4 1.5 1 0 0 1 1 1 0 GCK domain Glyco_hydro_61 PF03443.14 EGG03321.1 - 1.7e-25 90.2 0.2 2.9e-25 89.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CFEM PF05730.11 EGG03321.1 - 7.1e-07 29.2 5.7 7.1e-07 29.2 5.7 2.1 2 0 0 2 2 2 1 CFEM domain CBM_48 PF02922.18 EGG03321.1 - 0.078 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Plant_zn_clust PF10533.9 EGG03321.1 - 0.34 10.9 3.1 0.87 9.6 3.1 1.7 1 0 0 1 1 1 0 Plant zinc cluster domain DUF2540 PF10802.8 EGG03322.1 - 7.8e-05 22.7 1.2 1.1e+02 2.9 0.0 7.2 9 0 0 9 9 9 2 Protein of unknown function (DUF2540) MARVEL PF01284.23 EGG03323.1 - 1.4e-05 25.1 7.0 2.2e-05 24.5 7.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain MIOX PF05153.15 EGG03324.1 - 1.2e-116 388.7 0.4 1.4e-116 388.4 0.4 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 EGG03324.1 - 0.013 15.7 0.0 0.33 11.2 0.0 2.4 2 0 0 2 2 2 0 HD domain MIF4G PF02854.19 EGG03325.1 - 2.4e-50 171.1 6.5 1.7e-28 99.7 0.1 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 EGG03325.1 - 5.6e-30 104.8 5.3 9.8e-30 104.1 0.1 3.4 3 0 0 3 3 3 1 Up-frameshift suppressor 2 SNAPc_SNAP43 PF09808.9 EGG03327.1 - 6.5e-07 29.5 0.6 4.7e-06 26.7 0.1 2.3 2 1 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 EF-hand_2 PF09068.11 EGG03327.1 - 0.035 14.2 0.2 2.8 8.1 0.0 2.5 2 0 0 2 2 2 0 EF hand CPSF100_C PF13299.6 EGG03329.1 - 1.2e-33 116.7 4.3 5.6e-33 114.5 0.0 2.4 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EGG03329.1 - 5.4e-13 49.2 0.0 3.9e-12 46.4 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 EGG03329.1 - 0.00034 20.5 0.0 0.00085 19.2 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain FAD_binding_8 PF08022.12 EGG03330.1 - 1.9e-17 63.3 0.0 2.6e-12 46.8 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 EGG03330.1 - 1.4e-15 57.7 0.0 2.5e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGG03330.1 - 2.2e-15 56.9 10.1 2.2e-15 56.9 10.1 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component DUF3975 PF13126.6 EGG03330.1 - 2.1 8.9 7.0 6 7.4 7.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3975) Phage_holin_5_2 PF16079.5 EGG03330.1 - 6.8 7.1 8.1 0.62 10.4 0.8 2.6 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Amidohydro_2 PF04909.14 EGG03332.1 - 0.00017 21.5 0.0 0.00031 20.6 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase UCH PF00443.29 EGG03333.1 - 1.1e-41 143.1 0.1 1.1e-41 143.1 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG03333.1 - 1.2e-06 28.4 1.9 1.2e-06 28.4 1.9 3.5 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SF3a60_bindingd PF12108.8 EGG03333.1 - 0.038 13.9 0.6 0.11 12.4 0.6 1.9 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Baculo_PEP_C PF04513.12 EGG03335.1 - 0.31 11.1 5.2 0.17 11.9 0.7 2.4 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAD_binding_8 PF08022.12 EGG03336.1 - 2.4e-11 43.7 0.0 7.4e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EGG03336.1 - 6.1e-11 42.7 0.2 1.6e-08 34.8 0.2 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGG03336.1 - 0.078 13.1 6.9 0.59 10.2 0.5 2.5 1 1 1 2 2 2 0 Ferric reductase like transmembrane component GST_N PF02798.20 EGG03337.1 - 4.4e-17 62.2 0.0 1.2e-16 60.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG03337.1 - 9e-16 57.9 0.1 1.6e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG03337.1 - 1.2e-13 51.1 0.5 2.3e-13 50.2 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGG03337.1 - 1.4e-10 41.3 0.0 3.6e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGG03337.1 - 1.7e-10 41.2 0.0 3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGG03337.1 - 2.8e-05 24.1 0.3 0.00016 21.6 0.0 2.3 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.10 EGG03337.1 - 0.037 14.6 0.0 0.084 13.4 0.0 1.6 1 0 0 1 1 1 0 MetRS-N binding domain DUF4470 PF14737.6 EGG03340.1 - 1.7e-11 44.2 0.0 3.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 EGG03340.1 - 8.8e-06 25.3 0.7 0.00015 21.4 0.0 2.7 2 1 1 3 3 3 1 TPR repeat TPR_2 PF07719.17 EGG03340.1 - 0.0017 18.3 0.4 0.52 10.6 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG03340.1 - 0.0099 15.7 0.8 0.65 9.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG03340.1 - 0.018 15.3 0.2 0.066 13.5 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 EGG03341.1 - 4.8e-50 170.7 0.0 2.1e-49 168.6 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 EGG03341.1 - 0.001 17.9 0.0 0.0022 16.8 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 EGG03341.1 - 0.0049 16.2 0.0 0.0072 15.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Arf PF00025.21 EGG03343.1 - 3.7e-79 264.2 0.1 4.3e-79 264.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG03343.1 - 1.5e-14 54.2 0.0 2.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGG03343.1 - 3.6e-14 52.6 0.0 4.4e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGG03343.1 - 6e-13 48.7 0.0 6.4e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EGG03343.1 - 6.5e-13 48.6 0.8 4.2e-09 36.0 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGG03343.1 - 1.1e-10 41.3 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG03343.1 - 2.4e-06 27.6 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGG03343.1 - 0.0082 15.5 0.6 0.022 14.1 0.6 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase ADH_zinc_N PF00107.26 EGG03345.1 - 3.2e-22 78.9 0.0 5.5e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGG03345.1 - 1.8e-17 64.6 0.0 2.8e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG03345.1 - 0.055 13.4 0.0 0.2 11.5 0.0 1.9 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EGG03345.1 - 0.082 12.4 0.1 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase ACP_syn_III_C PF08541.10 EGG03345.1 - 0.088 13.0 0.1 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal TFIID_20kDa PF03847.13 EGG03346.1 - 2.3e-32 111.3 1.4 3.1e-32 110.9 1.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 EGG03346.1 - 4.7e-05 23.8 1.6 5.1e-05 23.6 0.3 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGG03346.1 - 0.00053 20.0 0.1 0.00065 19.8 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EGG03346.1 - 0.00087 19.5 0.1 0.0017 18.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2547 PF10818.8 EGG03347.1 - 0.034 15.1 0.2 2 9.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) Pectinesterase PF01095.19 EGG03350.1 - 1.1e-22 80.1 2.4 2.1e-22 79.2 2.4 1.3 1 1 0 1 1 1 1 Pectinesterase Pectinesterase PF01095.19 EGG03351.1 - 1.2e-27 96.4 1.0 1.5e-27 96.1 1.0 1.1 1 0 0 1 1 1 1 Pectinesterase Adeno_E1B_55K PF01696.17 EGG03351.1 - 0.094 11.4 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen NOT2_3_5 PF04153.18 EGG03352.1 - 4.7e-32 110.8 2.6 4.7e-32 110.8 2.6 1.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF4106 PF13388.6 EGG03352.1 - 5.4 6.1 15.0 7.7 5.6 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DS PF01916.17 EGG03354.1 - 1.1e-15 57.6 0.0 2.2e-13 50.1 0.0 2.0 1 1 1 2 2 2 2 Deoxyhypusine synthase FAR1 PF03101.15 EGG03356.1 - 0.008 16.8 0.8 0.021 15.5 0.8 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 EGG03356.1 - 0.0086 16.5 0.1 0.03 14.7 0.1 1.9 1 0 0 1 1 1 1 Transcription factor AFT CwfJ_C_1 PF04677.15 EGG03357.1 - 0.023 14.5 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 ABC_tran_CTD PF16326.5 EGG03357.1 - 0.38 11.0 0.1 0.38 11.0 0.1 3.3 4 0 0 4 4 4 0 ABC transporter C-terminal domain Cu-oxidase_3 PF07732.15 EGG03358.1 - 9.9e-31 106.2 0.0 1.8e-29 102.2 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EGG03358.1 - 7.1e-26 91.2 0.0 3.5e-24 85.7 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG03358.1 - 5.3e-22 78.0 4.9 2.5e-17 62.9 2.3 4.1 2 2 0 2 2 2 2 Multicopper oxidase DUF648 PF04890.13 EGG03360.1 - 0.31 10.8 4.6 0.44 10.2 4.5 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF648) Nucleos_tra2_C PF07662.13 EGG03362.1 - 8.7e-64 215.2 9.5 1.3e-63 214.6 0.9 2.3 2 0 0 2 2 2 2 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EGG03362.1 - 5.8e-19 68.5 6.9 5.8e-19 68.5 6.9 3.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus PALP PF00291.25 EGG03363.1 - 1.7e-56 191.8 0.1 2e-56 191.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ox_reductase_C PF08635.10 EGG03365.1 - 3.3e-56 188.9 0.0 4.9e-56 188.3 0.0 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 EGG03365.1 - 3.2e-22 79.6 0.0 5.5e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGG03365.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain SET PF00856.28 EGG03367.1 - 1.1e-15 58.4 1.8 3.9e-15 56.6 0.1 2.5 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EGG03367.1 - 7.9e-13 49.2 0.7 7.9e-13 49.2 0.7 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding G-patch PF01585.23 EGG03368.1 - 2.8e-10 39.9 0.5 5.7e-10 38.9 0.5 1.6 1 0 0 1 1 1 1 G-patch domain R3H PF01424.22 EGG03368.1 - 1.6e-09 37.6 0.0 3.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain Membralin PF09746.9 EGG03368.1 - 0.01 14.9 0.4 0.014 14.5 0.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein G-patch_2 PF12656.7 EGG03368.1 - 0.019 15.1 0.4 0.07 13.2 0.4 2.0 1 0 0 1 1 1 0 G-patch domain GPW_gp25 PF04965.14 EGG03368.1 - 0.13 12.0 0.0 0.64 9.8 0.0 2.0 2 0 0 2 2 2 0 Gene 25-like lysozyme CxC5 PF18718.1 EGG03369.1 - 3.7e-35 120.5 2.4 8.3e-35 119.4 2.4 1.6 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG03369.1 - 2.7e-20 72.4 3.5 8.3e-20 70.8 3.5 1.9 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 EGG03369.1 - 0.00015 21.6 0.5 0.00015 21.6 0.5 2.3 2 1 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases Alpha_kinase PF02816.18 EGG03370.1 - 2.5e-14 53.8 0.0 3.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family COesterase PF00135.28 EGG03371.1 - 1.2e-76 258.6 0.0 1.9e-76 258.0 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family PAP1 PF08601.10 EGG03372.1 - 1.1e-06 28.6 0.2 1.1e-06 28.6 0.2 2.6 2 1 0 2 2 2 1 Transcription factor PAP1 Clat_adaptor_s PF01217.20 EGG03373.1 - 6.4e-05 22.9 0.0 6.8e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1682 PF07946.14 EGG03374.1 - 4.1e-45 154.4 1.2 4.1e-45 154.4 0.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) TPR_22 PF18833.1 EGG03375.1 - 0.029 14.5 0.9 0.089 12.9 0.4 2.0 1 1 0 2 2 2 0 Tetratricopeptide repeat ChuX_HutX PF06228.13 EGG03375.1 - 0.17 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX Me-amine-dh_H PF06433.11 EGG03376.1 - 0.059 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) DUF2990 PF11693.8 EGG03376.1 - 0.094 12.9 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) IL6 PF00489.17 EGG03376.1 - 1.2 8.7 6.5 0.31 10.6 0.2 2.8 3 0 0 3 3 3 0 Interleukin-6/G-CSF/MGF family DUF16 PF01519.16 EGG03377.1 - 0.14 12.7 3.9 0.28 11.7 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 FAM104 PF15434.6 EGG03380.1 - 1.6 9.3 5.6 0.34 11.5 1.5 2.0 2 1 0 2 2 2 0 Family 104 HMG_box PF00505.19 EGG03381.1 - 0.026 14.9 0.0 0.67 10.4 0.0 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box DPBB_1 PF03330.18 EGG03384.1 - 0.011 16.0 0.3 0.17 12.2 0.0 2.6 2 1 0 2 2 2 0 Lytic transglycolase Pollen_allerg_1 PF01357.21 EGG03384.1 - 0.06 13.4 0.1 0.06 13.4 0.1 1.9 2 0 0 2 2 2 0 Pollen allergen DUF1687 PF07955.11 EGG03385.1 - 0.29 11.6 3.5 0.75 10.3 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1687) DUF1104 PF06518.11 EGG03385.1 - 8.3 6.9 6.7 8.7 6.8 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) zf-UBR PF02207.20 EGG03391.1 - 0.001 19.2 8.8 0.001 19.1 8.8 1.0 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) TPR_1 PF00515.28 EGG03392.1 - 9.8e-13 47.3 0.1 0.023 14.5 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG03392.1 - 1.4e-10 40.5 5.4 0.023 14.8 0.0 6.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGG03392.1 - 1.5e-08 34.2 0.0 0.032 13.9 0.0 4.0 3 1 1 4 4 4 2 TPR repeat TPR_8 PF13181.6 EGG03392.1 - 1.2e-07 31.3 0.1 1.4 9.4 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG03392.1 - 4.5e-07 30.1 0.9 0.016 16.0 0.4 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG03392.1 - 1.1e-06 28.5 0.2 0.00014 22.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG03392.1 - 6.9e-05 23.4 0.5 0.012 16.2 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG03392.1 - 0.0005 20.3 2.9 0.83 10.0 0.2 4.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG03392.1 - 0.00076 19.9 0.0 0.22 12.0 0.2 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG03392.1 - 0.003 17.7 0.1 0.018 15.2 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGG03392.1 - 0.047 13.8 0.3 2.6 8.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG03392.1 - 0.049 13.7 0.4 1.2e+02 3.1 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Homez PF11569.8 EGG03394.1 - 0.0025 17.3 0.4 0.0034 16.8 0.4 1.2 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Uds1 PF15456.6 EGG03396.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Up-regulated During Septation SAP PF02037.27 EGG03397.1 - 0.00063 19.4 0.8 0.0012 18.5 0.8 1.4 1 0 0 1 1 1 1 SAP domain SAP PF02037.27 EGG03398.1 - 0.016 15.0 0.6 0.12 12.1 0.0 2.6 3 0 0 3 3 3 0 SAP domain Baculo_PEP_N PF04512.12 EGG03398.1 - 0.064 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus Vac14_Fig4_bd PF11916.8 EGG03398.1 - 0.092 12.4 0.3 7 6.3 0.1 2.2 2 0 0 2 2 2 0 Vacuolar protein 14 C-terminal Fig4p binding SAP PF02037.27 EGG03399.1 - 0.0012 18.6 0.5 0.0021 17.7 0.5 1.4 1 0 0 1 1 1 1 SAP domain DUF3379 PF11859.8 EGG03399.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) Nucleolin_bd PF16725.5 EGG03401.1 - 0.075 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Nucleolin binding domain DUF3774 PF12609.8 EGG03404.1 - 0.026 15.5 1.3 3.2 8.8 0.1 2.5 2 0 0 2 2 2 0 Wound-induced protein Peptidase_S28 PF05577.12 EGG03405.1 - 2.8e-56 191.2 0.0 1.4e-55 188.8 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 YwpF PF14183.6 EGG03406.1 - 0.19 11.7 0.1 0.29 11.1 0.1 1.2 1 0 0 1 1 1 0 YwpF-like protein Clat_adaptor_s PF01217.20 EGG03410.1 - 7.4e-47 158.9 2.7 8.7e-47 158.6 2.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2072 PF09845.9 EGG03411.1 - 1.6 9.0 4.5 0.48 10.7 0.3 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein BTB PF00651.31 EGG03412.1 - 1.6e-08 34.8 0.7 0.00085 19.5 0.0 3.0 3 0 0 3 3 3 2 BTB/POZ domain Orbi_VP5 PF00901.17 EGG03412.1 - 0.066 11.6 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Nop14 PF04147.12 EGG03412.1 - 0.5 8.5 9.0 0.71 8.0 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_bind PF08675.11 EGG03413.1 - 0.013 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA binding domain RRM_1 PF00076.22 EGG03413.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Retrotran_gag_2 PF14223.6 EGG03414.1 - 1.6e-07 31.1 0.8 3.4e-07 30.0 0.8 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Mad3_BUB1_I PF08311.12 EGG03414.1 - 0.072 13.1 0.3 0.072 13.1 0.3 1.6 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 Polysacc_lyase PF14099.6 EGG03415.1 - 0.0051 16.7 0.1 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide lyase Inv-AAD PF18785.1 EGG03416.1 - 6.3e-26 90.7 0.1 2.8e-25 88.7 0.1 1.8 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EGG03416.1 - 8.5e-10 38.4 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 EGG03416.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.3 1 1 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC3 PF18771.1 EGG03416.1 - 0.024 14.8 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 NAD1 PF18778.1 EGG03416.1 - 0.17 12.0 0.0 0.27 11.3 0.0 1.4 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 DUF410 PF04190.13 EGG03417.1 - 1.7e-55 188.6 0.0 2.4e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Myb_DNA-binding PF00249.31 EGG03417.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Ribosomal_L41 PF05162.13 EGG03419.1 - 0.025 14.7 7.7 0.04 14.0 7.7 1.4 1 0 0 1 1 1 0 Ribosomal protein L41 AA_permease PF00324.21 EGG03420.1 - 7.5e-124 413.9 35.3 9e-124 413.7 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGG03420.1 - 5.8e-35 120.9 36.5 7.1e-35 120.6 36.5 1.1 1 0 0 1 1 1 1 Amino acid permease Not1 PF04054.15 EGG03421.1 - 3.8e-113 378.1 0.3 1.8e-112 375.9 0.0 2.0 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.7 EGG03421.1 - 3.1e-46 156.9 0.0 1.3e-45 154.9 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EGG03421.1 - 1.9e-45 154.4 0.0 4.5e-45 153.1 0.0 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EGG03421.1 - 4.4e-45 153.4 0.0 1.4e-44 151.8 0.0 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_CAF1_bind PF16415.5 EGG03421.1 - 8.8e-13 48.2 9.2 3.3e-06 26.6 0.1 3.9 3 1 1 4 4 4 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Paz_1 PF18349.1 EGG03421.1 - 0.059 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 PAZ domain Glyco_hydro_47 PF01532.20 EGG03424.1 - 0.00066 18.7 0.0 0.00095 18.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.20 EGG03425.1 - 5e-123 411.4 0.0 5.7e-123 411.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Hid1 PF12722.7 EGG03426.1 - 4e-114 382.5 2.8 2.1e-74 251.2 0.0 5.3 3 3 0 3 3 3 3 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EGG03426.1 - 1.3e-64 218.7 0.0 2.1e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF2463 PF09591.10 EGG03426.1 - 0.036 13.9 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) SLD3 PF08639.10 EGG03427.1 - 1.8e-19 69.9 10.8 3e-19 69.2 10.8 1.3 1 1 0 1 1 1 1 DNA replication regulator SLD3 DUF4007 PF13182.6 EGG03427.1 - 0.01 14.9 1.1 0.017 14.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) S36_mt PF10937.8 EGG03427.1 - 0.81 11.3 3.8 6.2 8.5 0.8 2.8 1 1 1 2 2 2 0 Ribosomal protein S36, mitochondrial MIP-T3_C PF17749.1 EGG03429.1 - 0.29 11.1 3.6 5.6 6.9 0.0 3.3 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Hydrolase_4 PF12146.8 EGG03430.1 - 3e-08 33.2 0.0 0.0024 17.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG03430.1 - 6.1e-06 27.0 0.1 7.4e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EGG03430.1 - 0.0071 16.2 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 EGG03430.1 - 0.033 13.8 0.0 0.51 9.9 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF1749 PF08538.10 EGG03430.1 - 0.094 11.8 0.0 7.1 5.6 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1749) Ser_hydrolase PF06821.13 EGG03430.1 - 0.2 11.5 0.1 0.43 10.4 0.1 1.6 1 1 0 1 1 1 0 Serine hydrolase Abhydrolase_4 PF08386.10 EGG03430.1 - 0.2 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Peptidase_C15 PF01470.17 EGG03431.1 - 5.4e-12 46.3 0.0 1.1e-05 25.7 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase Glyco_hydro_63N PF16923.5 EGG03433.1 - 1.2 9.2 4.3 0.55 10.3 1.0 1.9 1 1 1 2 2 2 0 Glycosyl hydrolase family 63 N-terminal domain RRM_1 PF00076.22 EGG03434.1 - 5.9e-21 74.1 0.2 4.7e-10 39.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG03434.1 - 1.8e-05 24.3 0.0 0.00041 19.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG03434.1 - 0.00028 20.7 0.0 0.016 15.1 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EGG03434.1 - 0.033 14.3 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 MARVEL PF01284.23 EGG03435.1 - 0.074 13.1 10.4 0.11 12.6 9.8 1.6 1 1 0 1 1 1 0 Membrane-associating domain NB-LRR PF12061.8 EGG03437.1 - 0.078 12.3 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Late blight resistance protein R1 ABC1 PF03109.16 EGG03438.1 - 2.1e-22 79.5 0.0 6e-14 52.2 0.0 2.8 3 0 0 3 3 3 2 ABC1 family Bac_export_1 PF01311.20 EGG03438.1 - 0.17 11.4 0.2 0.8 9.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial export proteins, family 1 Homeodomain PF00046.29 EGG03439.1 - 1.3e-09 37.8 0.2 3e-09 36.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGG03439.1 - 5.4e-06 26.2 2.8 6.4e-06 26.0 1.3 2.0 2 0 0 2 2 2 1 Homeobox KN domain DUF1759 PF03564.15 EGG03441.1 - 0.01 15.8 0.1 0.03 14.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Homeodomain PF00046.29 EGG03442.1 - 0.0018 18.1 0.0 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 Homeodomain LacI PF00356.21 EGG03443.1 - 0.074 12.9 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF659 PF04937.15 EGG03446.1 - 0.067 13.0 0.2 0.17 11.7 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF 659) Mg_trans_NIPA PF05653.14 EGG03447.1 - 9.9e-20 70.8 18.4 1.8e-13 50.3 6.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA HNF-1_N PF04814.13 EGG03447.1 - 0.24 12.0 0.1 0.24 12.0 0.1 1.8 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus ArAE_2 PF10334.9 EGG03448.1 - 3.3e-08 33.6 1.7 7.4e-05 22.7 0.1 2.5 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 EGG03448.1 - 0.00016 21.8 25.2 0.0028 17.8 4.6 2.7 2 0 0 2 2 2 2 Fusaric acid resistance protein-like Cytomega_gL PF01801.16 EGG03448.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L Stc1 PF12898.7 EGG03449.1 - 2.9e-12 46.9 13.9 4.2e-10 40.0 9.7 2.4 1 1 1 2 2 2 2 Stc1 domain DUF4428 PF14471.6 EGG03449.1 - 0.011 15.6 0.2 0.011 15.6 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) UCH_1 PF13423.6 EGG03449.1 - 0.033 13.8 5.2 0.043 13.4 5.2 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase FpoO PF10621.9 EGG03449.1 - 0.041 14.2 4.6 0.27 11.5 0.9 2.4 1 1 1 2 2 2 0 F420H2 dehydrogenase subunit FpoO zf-CHY PF05495.12 EGG03449.1 - 0.082 13.4 10.1 1.7 9.2 8.9 2.8 1 1 1 2 2 2 0 CHY zinc finger C1_2 PF03107.16 EGG03449.1 - 1.2 9.6 8.4 0.17 12.3 1.4 2.8 3 0 0 3 3 3 0 C1 domain zinc_ribbon_15 PF17032.5 EGG03449.1 - 2 9.2 12.3 0.3 11.9 3.0 2.9 1 1 2 3 3 3 0 zinc-ribbon family zinc-ribbons_6 PF07191.12 EGG03449.1 - 2.4 8.2 10.1 6.7 6.8 6.6 2.8 2 1 0 2 2 2 0 zinc-ribbons C1_1 PF00130.22 EGG03449.1 - 2.6 8.0 11.5 14 5.7 0.0 3.3 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.10 EGG03449.1 - 5.8 6.8 11.4 0.81 9.5 0.2 3.3 4 0 0 4 4 4 0 A2L zinc ribbon domain DUF1660 PF07874.11 EGG03449.1 - 9.2 6.8 17.8 0.37 11.3 1.8 3.6 1 1 2 3 3 3 0 Prophage protein (DUF1660) GCH_III PF05165.12 EGG03450.1 - 0.21 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase III NRDE-2 PF08424.10 EGG03451.1 - 6.1e-63 212.9 11.2 1.7e-38 132.5 0.1 4.2 3 1 1 4 4 4 3 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EGG03451.1 - 0.00039 21.0 2.0 10 7.2 0.0 6.3 6 1 1 7 7 7 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGG03451.1 - 0.0017 18.3 4.4 4.9 7.2 0.1 4.4 5 0 0 5 5 5 3 Mad3/BUB1 homology region 1 zf-CCHC_6 PF15288.6 EGG03453.1 - 0.017 15.0 1.3 0.017 15.0 1.3 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 EGG03453.1 - 0.07 13.2 2.3 0.13 12.3 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGG03453.1 - 0.16 11.8 0.5 0.25 11.1 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle Alpha_kinase PF02816.18 EGG03455.1 - 8.6e-14 52.1 1.6 1.2e-13 51.6 1.6 1.2 1 0 0 1 1 1 1 Alpha-kinase family Sod_Cu PF00080.20 EGG03456.1 - 1.1e-15 58.0 0.7 1.7e-15 57.4 0.7 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 EGG03456.1 - 0.028 15.4 0.1 0.045 14.7 0.1 1.3 1 0 0 1 1 1 0 CHRD domain Sod_Cu PF00080.20 EGG03458.1 - 1e-15 58.2 0.1 1.5e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 EGG03458.1 - 0.043 14.8 0.0 0.071 14.1 0.0 1.5 1 0 0 1 1 1 0 CHRD domain Pyrid_oxidase_2 PF13883.6 EGG03459.1 - 8.8e-23 81.1 0.0 1.1e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3392 PF11872.8 EGG03460.1 - 0.0047 17.2 0.0 0.0072 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3392) SWI-SNF_Ssr4 PF08549.10 EGG03460.1 - 0.01 14.5 0.8 0.013 14.2 0.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) AvrM_N PF18247.1 EGG03462.1 - 4.2e-31 106.7 1.8 1.6e-30 104.8 0.5 2.7 2 0 0 2 2 2 1 Flax-rust effector AvrM N-terminal domain AvrM-A PF18241.1 EGG03462.1 - 4.9e-31 108.1 6.8 4.9e-31 108.1 6.8 2.6 3 0 0 3 3 3 1 Flax-rust effector AvrM-A AvrM-A PF18241.1 EGG03463.1 - 6.7e-58 195.3 11.0 6.7e-58 195.3 11.0 2.2 2 0 0 2 2 2 2 Flax-rust effector AvrM-A AvrM_N PF18247.1 EGG03463.1 - 1.3e-15 57.1 0.6 1.3e-15 57.1 0.6 2.9 3 0 0 3 3 3 1 Flax-rust effector AvrM N-terminal domain IL22 PF14565.6 EGG03463.1 - 0.036 14.3 2.1 0.07 13.4 0.1 2.2 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor TetR_C_24 PF17932.1 EGG03463.1 - 0.49 10.7 3.2 3.2 8.0 0.3 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RIBIOP_C PF04950.12 EGG03464.1 - 1.1e-91 307.3 0.3 3.1e-91 305.8 0.0 1.8 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGG03464.1 - 2e-22 79.1 0.0 5.4e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 EGG03464.1 - 1.2e-05 24.9 0.0 0.0015 18.1 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGG03464.1 - 1.4e-05 25.5 0.2 6.7e-05 23.3 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG03464.1 - 4.6e-05 23.7 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGG03464.1 - 0.00038 20.9 0.0 0.00073 20.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGG03464.1 - 0.00059 19.5 0.1 0.016 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EGG03464.1 - 0.0016 17.7 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 EGG03464.1 - 0.0018 18.8 0.3 0.011 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGG03464.1 - 0.002 18.2 0.1 0.0062 16.6 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGG03464.1 - 0.0059 17.1 0.3 0.02 15.4 0.0 2.0 2 0 0 2 2 1 1 ABC transporter AAA_28 PF13521.6 EGG03464.1 - 0.006 16.8 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGG03464.1 - 0.01 16.2 0.1 0.44 11.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGG03464.1 - 0.01 15.7 0.0 0.029 14.3 0.0 1.8 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EGG03464.1 - 0.037 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGG03464.1 - 0.038 14.2 0.0 0.038 14.2 0.0 2.8 4 0 0 4 4 3 0 AAA domain AAA_19 PF13245.6 EGG03464.1 - 0.039 14.3 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EGG03464.1 - 0.051 13.4 0.0 0.5 10.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EGG03464.1 - 0.059 13.3 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 EGG03464.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 EGG03464.1 - 0.074 12.8 0.4 0.18 11.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 EGG03464.1 - 0.085 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EGG03464.1 - 0.11 12.9 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 EGG03464.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EGG03464.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.9 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 EGG03465.1 - 8e-28 97.5 0.0 9.8e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG03465.1 - 1e-15 57.7 0.0 1.3e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG03465.1 - 2.9e-09 36.2 0.0 3.8e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGG03465.1 - 0.0011 19.0 0.1 0.0077 16.2 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EGG03465.1 - 0.031 13.2 0.1 0.046 12.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 EGG03465.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAD_SRA PF02182.17 EGG03470.1 - 7.9e-54 181.6 0.3 1.8e-53 180.4 0.0 1.8 2 0 0 2 2 2 1 SAD/SRA domain Ndc1_Nup PF09531.10 EGG03470.1 - 0.43 9.2 1.6 0.57 8.8 1.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex16 PF08610.10 EGG03470.1 - 0.92 8.6 2.6 1.7 7.8 2.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SAD_SRA PF02182.17 EGG03472.1 - 1.1e-53 181.2 0.3 2.9e-53 179.8 0.0 1.9 2 0 0 2 2 2 1 SAD/SRA domain CxC1 PF18802.1 EGG03473.1 - 5.4e-29 100.4 0.0 1.3e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG03473.1 - 3.4e-08 33.6 0.0 1.1e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGG03473.1 - 0.0046 16.6 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC3 PF18804.1 EGG03473.1 - 0.022 14.6 0.3 0.056 13.3 0.1 1.8 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases SCAMP PF04144.13 EGG03473.1 - 0.11 12.8 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 SCAMP family Retrotran_gag_2 PF14223.6 EGG03474.1 - 8.1e-05 22.3 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.6 EGG03474.1 - 0.11 12.4 2.9 0.2 11.5 2.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.25 EGG03476.1 - 1.1e-60 205.3 0.1 1.3e-60 205.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG03476.1 - 6e-35 120.8 0.0 6.7e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG03476.1 - 1.7e-05 24.9 0.1 0.00013 22.0 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGG03476.1 - 0.00088 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGG03476.1 - 0.00089 18.9 0.8 0.0028 17.3 0.9 1.7 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EGG03476.1 - 0.0013 18.1 0.0 0.0074 15.6 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGG03476.1 - 0.0019 17.2 0.1 0.0019 17.2 0.1 1.9 2 1 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 EGG03476.1 - 0.042 13.5 0.2 9.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Agro_virD5 PF04730.12 EGG03478.1 - 0.064 11.8 0.0 0.064 11.8 0.0 1.0 1 0 0 1 1 1 0 Agrobacterium VirD5 protein Glyco_transf_90 PF05686.12 EGG03480.1 - 9.2e-15 54.4 4.1 7.1e-14 51.5 4.1 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 Syntaphilin PF15290.6 EGG03480.1 - 0.08 12.6 0.5 0.14 11.8 0.5 1.3 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp IF-2B PF01008.17 EGG03481.1 - 1.1e-54 185.6 0.1 1.3e-54 185.3 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Kinesin_assoc PF16183.5 EGG03481.1 - 0.054 13.6 0.3 0.1 12.8 0.3 1.5 1 0 0 1 1 1 0 Kinesin-associated SLX9 PF15341.6 EGG03482.1 - 1.9e-15 57.4 8.1 3.3e-15 56.6 8.1 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 T5orf172 PF10544.9 EGG03482.1 - 0.46 11.1 7.6 0.14 12.7 2.2 2.5 2 1 1 3 3 3 0 T5orf172 domain Erf4 PF10256.9 EGG03483.1 - 2.2e-26 92.2 0.0 3.4e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Macoilin PF09726.9 EGG03483.1 - 2.6 6.5 7.2 3.4 6.1 7.2 1.0 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 EGG03483.1 - 6.7 6.5 16.2 8.7 6.2 16.2 1.1 1 0 0 1 1 1 0 SPX domain Glyco_transf_8 PF01501.20 EGG03486.1 - 1.9e-27 96.4 0.6 1.3e-26 93.7 0.6 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 DASH_Dad2 PF08654.10 EGG03488.1 - 2e-24 85.8 1.3 2.5e-24 85.6 1.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DUF1741 PF08427.10 EGG03489.1 - 2.5e-28 99.3 0.1 2.6e-27 96.0 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1741) DUF3919 PF13057.6 EGG03489.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) CxC6 PF18721.1 EGG03490.1 - 1.8e-19 69.8 1.6 1.8e-19 69.8 1.6 2.2 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 EGG03490.1 - 9.5e-16 57.9 2.2 4.2e-13 49.4 2.2 2.6 1 1 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Vel1p PF10339.9 EGG03491.1 - 0.0065 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Yeast-specific zinc responsive DUF3484 PF11983.8 EGG03492.1 - 0.18 13.0 2.4 0.54 11.4 2.4 1.9 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Pyrid_oxidase_2 PF13883.6 EGG03494.1 - 4.2e-22 78.9 0.0 6.8e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF883 PF05957.13 EGG03494.1 - 0.081 13.5 0.3 0.31 11.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Pyridox_ox_2 PF12900.7 EGG03494.1 - 0.11 12.5 1.8 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase AATF-Che1 PF13339.6 EGG03494.1 - 0.29 11.8 9.2 0.18 12.5 5.7 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor CENP-H PF05837.12 EGG03494.1 - 0.53 10.7 12.4 0.094 13.1 7.9 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) LMBR1 PF04791.16 EGG03495.1 - 0.84 8.5 2.2 0.86 8.4 2.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CxC1 PF18802.1 EGG03496.1 - 9.2e-11 41.8 0.1 2.5e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG03496.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases DDE_Tnp_1 PF01609.21 EGG03497.1 - 0.044 13.4 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain HMG_box PF00505.19 EGG03497.1 - 0.15 12.5 0.3 0.41 11.1 0.3 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box Pal1 PF08316.11 EGG03499.1 - 2.5e-07 31.6 2.0 7.2e-07 30.0 2.0 1.8 1 0 0 1 1 1 1 Pal1 cell morphology protein Ribosomal_S7e PF01251.18 EGG03500.1 - 7.8e-85 283.3 0.7 9e-85 283.1 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e TMEM135_C_rich PF15982.5 EGG03501.1 - 0.0019 18.8 0.5 0.012 16.2 0.1 2.4 2 1 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Homeobox_KN PF05920.11 EGG03504.1 - 1.9e-09 37.3 0.1 3.5e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EGG03504.1 - 2.6e-06 27.2 0.3 8.1e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 EGG03504.1 - 0.049 13.1 0.2 0.049 13.1 0.2 3.1 4 0 0 4 4 4 0 Homeodomain leucine-zipper encoding, Homez SIP1 PF04938.12 EGG03507.1 - 0.036 13.8 0.1 0.46 10.1 0.0 2.1 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Pkinase PF00069.25 EGG03511.1 - 6.1e-60 202.8 0.0 6.8e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG03511.1 - 3.1e-43 147.9 0.0 3.4e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EGG03511.1 - 1.5e-05 24.6 0.1 7.1e-05 22.4 0.1 1.8 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 EGG03511.1 - 0.00032 20.1 0.2 0.00071 19.0 0.2 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG03511.1 - 0.00051 19.5 0.2 0.00077 18.9 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGG03511.1 - 0.0014 18.3 0.2 0.0032 17.1 0.1 1.6 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EGG03511.1 - 0.0029 16.4 0.1 0.0029 16.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGG03511.1 - 0.031 14.2 0.1 0.04 13.8 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG03511.1 - 0.09 11.7 0.2 0.11 11.4 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Nramp PF01566.18 EGG03512.1 - 2e-52 178.3 15.9 7.1e-52 176.5 15.9 1.7 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein DUF3682 PF12446.8 EGG03515.1 - 0.73 10.3 6.3 1.4 9.4 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF4448 PF14610.6 EGG03521.1 - 0.0014 18.4 0.1 0.0027 17.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 EGG03521.1 - 0.056 14.3 0.1 0.21 12.5 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DNA_pol3_tau_4 PF12168.8 EGG03521.1 - 0.13 12.8 0.1 0.13 12.8 0.1 2.8 3 1 1 4 4 4 0 DNA polymerase III subunits tau domain IV DnaB-binding DUF3377 PF11857.8 EGG03522.1 - 0.035 14.0 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) G-patch_2 PF12656.7 EGG03523.1 - 2.1e-20 72.5 0.0 1e-19 70.4 0.0 2.3 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 EGG03523.1 - 0.039 13.9 0.2 0.088 12.7 0.2 1.7 1 0 0 1 1 1 0 G-patch domain Nudix_N_2 PF14803.6 EGG03524.1 - 0.048 13.6 1.8 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal Bestrophin PF01062.21 EGG03525.1 - 4.8e-28 98.4 0.4 6.3e-23 81.6 0.0 2.9 2 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel SYF2 PF08231.12 EGG03526.1 - 8.3e-52 175.8 18.8 8.3e-52 175.8 18.8 1.6 2 0 0 2 2 2 1 SYF2 splicing factor Fib_alpha PF08702.10 EGG03526.1 - 2.7 8.1 5.1 2 8.6 1.7 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PINIT PF14324.6 EGG03529.1 - 6.6e-38 130.3 0.2 1.5e-37 129.2 0.2 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EGG03529.1 - 2.6e-18 65.5 1.0 2.6e-18 65.5 1.0 2.1 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EGG03529.1 - 3.9e-06 26.6 0.2 3.9e-06 26.6 0.2 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 EGG03529.1 - 0.055 13.2 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 SAP domain DUF2423 PF10338.9 EGG03530.1 - 0.18 12.1 0.1 0.44 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) Mitoc_mL59 PF18126.1 EGG03533.1 - 2e-06 28.1 3.0 4.3e-06 27.0 2.3 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 HOOK PF05622.12 EGG03534.1 - 3.2e-45 154.5 91.1 6.7e-43 146.9 69.7 2.5 1 1 0 2 2 2 2 HOOK protein Laminin_II PF06009.12 EGG03534.1 - 0.002 18.1 4.4 0.002 18.1 4.4 6.6 5 2 3 8 8 8 1 Laminin Domain II TPR_MLP1_2 PF07926.12 EGG03534.1 - 0.0047 17.0 3.0 0.0047 17.0 3.0 8.0 7 2 0 7 7 7 3 TPR/MLP1/MLP2-like protein ThiS-like PF14453.6 EGG03537.1 - 0.00021 21.2 0.2 53 4.0 0.0 4.3 4 0 0 4 4 4 0 ThiS-like ubiquitin HMG_box_5 PF14887.6 EGG03537.1 - 0.0025 17.7 7.8 24 5.0 0.1 4.4 4 0 0 4 4 4 0 HMG (high mobility group) box 5 MAPKK1_Int PF08923.10 EGG03537.1 - 0.0035 17.1 0.2 82 3.0 0.0 4.0 4 0 0 4 4 4 0 Mitogen-activated protein kinase kinase 1 interacting Oest_recep PF02159.15 EGG03537.1 - 0.016 15.7 6.6 4.2 7.9 0.1 3.5 4 0 0 4 4 4 0 Oestrogen receptor Flagellin_N PF00669.20 EGG03537.1 - 0.017 15.2 4.2 11 6.1 0.1 3.9 4 0 0 4 4 4 0 Bacterial flagellin N-terminal helical region Lipid_bd PF12888.7 EGG03537.1 - 0.02 15.3 1.3 37 4.8 0.0 4.0 4 0 0 4 4 4 0 Lipid-binding putative hydrolase mCpol PF18182.1 EGG03537.1 - 0.043 14.2 2.0 31 5.0 0.0 3.9 4 0 0 4 4 4 0 minimal CRISPR polymerase domain Lac_bphage_repr PF06543.12 EGG03537.1 - 0.13 12.2 0.8 98 3.0 0.0 3.9 4 0 0 4 4 4 0 Lactococcus bacteriophage repressor SPT6_acidic PF14632.6 EGG03537.1 - 0.81 10.3 5.7 1.1e+02 3.4 0.1 3.9 4 0 0 4 4 4 0 Acidic N-terminal SPT6 DUF3708 PF12501.8 EGG03537.1 - 0.91 9.3 14.9 7.4 6.3 0.4 4.4 1 1 3 4 4 4 0 Phosphate ATP-binding cassette transporter PCRF PF03462.18 EGG03538.1 - 0.094 12.6 1.8 0.19 11.5 1.8 1.5 1 0 0 1 1 1 0 PCRF domain DASH_Spc19 PF08287.11 EGG03538.1 - 0.18 11.7 8.1 0.55 10.1 8.1 1.8 1 0 0 1 1 1 0 Spc19 GBR_NSP5 PF17580.2 EGG03538.1 - 0.49 10.2 5.3 0.26 11.1 2.0 2.2 2 0 0 2 2 2 0 Group B Rotavirus Non-structural protein 5 Dynamin_N PF00350.23 EGG03542.1 - 1e-41 142.8 0.0 3.5e-41 141.0 0.0 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EGG03542.1 - 1.6e-09 37.4 0.4 5.8e-09 35.6 0.3 1.9 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EGG03542.1 - 3.3e-05 23.9 0.0 0.0001 22.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EGG03542.1 - 0.014 15.2 0.1 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGG03542.1 - 0.057 13.1 3.4 0.1 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Pyr_redox_2 PF07992.14 EGG03543.1 - 1.4e-07 31.1 0.0 4.6e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG03543.1 - 0.00064 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGG03543.1 - 0.032 14.4 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Gpi16 PF04113.14 EGG03544.1 - 3.3e-122 408.8 0.0 1e-121 407.2 0.0 1.8 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Gly_transf_sug PF04488.15 EGG03546.1 - 1.5e-20 73.7 0.0 3.2e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EGG03546.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 EGG03546.1 - 0.33 10.2 0.3 0.51 9.6 0.3 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain SUIM_assoc PF16619.5 EGG03546.1 - 1.7 8.8 10.0 5 7.3 10.0 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 BCDHK_Adom3 PF10436.9 EGG03547.1 - 5.7e-41 140.1 1.9 7.9e-41 139.6 1.9 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGG03547.1 - 0.0035 17.8 0.0 0.016 15.7 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dicty_REP PF05086.12 EGG03548.1 - 0.0028 15.7 3.9 0.0033 15.5 3.9 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein MAP7 PF05672.11 EGG03548.1 - 0.37 10.5 9.5 0.74 9.5 9.5 1.5 1 1 0 1 1 1 0 MAP7 (E-MAP-115) family NOA36 PF06524.12 EGG03548.1 - 3.4 6.9 14.8 5.3 6.3 14.8 1.2 1 0 0 1 1 1 0 NOA36 protein Keratin_B2 PF01500.17 EGG03549.1 - 0.2 11.6 4.8 0.076 13.0 1.2 2.3 2 1 0 2 2 2 0 Keratin, high sulfur B2 protein Vps62 PF06101.11 EGG03552.1 - 7.1e-05 21.3 0.4 0.16 10.3 0.0 2.5 3 0 0 3 3 3 2 Vacuolar protein sorting-associated protein 62 Hamartin PF04388.12 EGG03554.1 - 5.2 5.6 8.4 6.5 5.3 8.4 1.1 1 0 0 1 1 1 0 Hamartin protein DUF1758 PF05585.12 EGG03555.1 - 0.029 14.2 0.6 0.053 13.3 0.2 1.6 2 0 0 2 2 2 0 Putative peptidase (DUF1758) DUF2967 PF11179.8 EGG03559.1 - 0.044 11.9 2.7 0.05 11.7 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Helitron_like_N PF14214.6 EGG03560.1 - 0.011 15.9 0.9 0.011 15.9 0.9 1.9 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus AMPKBI PF04739.15 EGG03560.1 - 0.02 15.1 10.7 0.036 14.3 2.4 2.4 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain SNF2_N PF00176.23 EGG03562.1 - 7.7e-56 189.3 0.9 1.5e-55 188.4 0.9 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG03562.1 - 9.9e-14 51.6 0.0 3e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_11 PF13086.6 EGG03562.1 - 0.0027 17.5 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EGG03562.1 - 0.0085 15.9 0.0 0.048 13.4 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGG03562.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit N_BRCA1_IG PF16158.5 EGG03565.1 - 8.7e-31 106.7 0.1 9.8e-31 106.5 0.1 1.0 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene RNA_pol_Rpb1_5 PF04998.17 EGG03566.1 - 2e-90 302.9 0.0 6.1e-90 301.3 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGG03566.1 - 4.7e-63 212.4 0.2 9.7e-63 211.3 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGG03566.1 - 2e-35 122.0 0.0 6.7e-35 120.3 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EGG03566.1 - 6.7e-32 111.1 2.3 4.5e-27 95.2 0.1 3.0 2 1 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EGG03566.1 - 1.6e-21 76.2 0.8 4.3e-21 74.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DUF4344 PF14247.6 EGG03566.1 - 0.11 12.1 0.2 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Putative metallopeptidase F-box-like PF12937.7 EGG03567.1 - 2.1e-06 27.5 1.0 6.4e-06 26.0 0.5 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGG03567.1 - 0.00022 21.0 0.2 0.034 14.0 0.1 2.6 2 0 0 2 2 2 2 F-box domain DUF2608 PF11019.8 EGG03567.1 - 0.042 13.3 0.3 1.1 8.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) NIPSNAP PF07978.13 EGG03568.1 - 3.4e-38 130.0 0.4 9e-27 93.3 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP Ntox8 PF15545.6 EGG03568.1 - 0.14 12.3 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial toxin 8 TFIIA PF03153.13 EGG03569.1 - 0.0017 18.5 8.6 0.0017 18.5 8.6 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 EGG03569.1 - 0.0054 16.5 15.0 0.0054 16.5 15.0 2.6 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein Asp-B-Hydro_N PF05279.11 EGG03571.1 - 7.2 6.6 12.9 12 5.8 12.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Lipase_3 PF01764.25 EGG03572.1 - 7.3e-07 29.1 0.0 2e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGG03572.1 - 0.011 16.3 0.1 0.018 15.7 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Rac1 PF09632.10 EGG03572.1 - 0.14 11.3 0.1 0.2 10.8 0.1 1.1 1 0 0 1 1 1 0 Rac1-binding domain DnaJ_C PF01556.18 EGG03573.1 - 1.5e-35 122.4 0.2 2e-35 122.1 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGG03573.1 - 4.2e-23 81.3 2.4 6.2e-23 80.7 2.4 1.3 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L7Ae PF01248.26 EGG03574.1 - 1e-25 89.3 0.1 1.3e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EGG03574.1 - 0.00021 21.4 0.1 0.00024 21.2 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EGG03574.1 - 0.0026 17.6 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain FlxA PF14282.6 EGG03574.1 - 0.048 13.6 5.0 0.14 12.1 1.3 2.2 2 0 0 2 2 2 0 FlxA-like protein DinI PF06183.13 EGG03575.1 - 0.39 11.1 1.6 13 6.2 0.0 2.4 2 0 0 2 2 2 0 DinI-like family Calreticulin PF00262.18 EGG03582.1 - 2e-168 560.0 11.2 2.5e-168 559.6 11.2 1.1 1 0 0 1 1 1 1 Calreticulin family Wzy_C_2 PF11846.8 EGG03582.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Virulence factor membrane-bound polymerase, C-terminal Aldo_ket_red PF00248.21 EGG03583.1 - 1.1e-41 143.0 0.0 1.7e-41 142.4 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Sod_Cu PF00080.20 EGG03584.1 - 2.6e-07 30.9 0.1 1.2e-06 28.8 0.1 2.0 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PKHD_C PF18331.1 EGG03586.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain Cyclin PF08613.11 EGG03587.1 - 2.8e-31 109.1 0.3 2.8e-31 109.1 0.3 2.1 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGG03587.1 - 0.028 14.2 0.8 0.081 12.7 0.6 1.8 1 1 0 1 1 1 0 Cyclin, N-terminal domain ALAD PF00490.21 EGG03588.1 - 4e-122 407.3 0.0 4.9e-122 407.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Ebp2 PF05890.12 EGG03590.1 - 6.6e-46 157.0 17.6 9.5e-46 156.5 17.6 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 PPIP5K2_N PF18086.1 EGG03590.1 - 0.07 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain zf-MYND PF01753.18 EGG03593.1 - 2.9e-09 36.9 14.5 2.9e-09 36.9 14.5 2.1 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 EGG03593.1 - 0.043 13.9 6.0 0.098 12.8 6.0 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Torus PF16131.5 EGG03594.1 - 4.5e-39 133.5 1.5 4.5e-39 133.5 1.5 1.9 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 EGG03594.1 - 3.1e-07 30.1 0.0 8e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG03594.1 - 0.0017 18.3 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TonB_N PF16031.5 EGG03594.1 - 0.008 16.7 3.2 0.008 16.7 3.2 2.2 2 0 0 2 2 2 1 TonB polyproline region zf_CCCH_4 PF18345.1 EGG03594.1 - 0.055 13.6 6.2 0.1 12.7 6.2 1.5 1 0 0 1 1 1 0 Zinc finger domain Trypan_PARP PF05887.11 EGG03594.1 - 1 9.4 8.8 0.066 13.2 2.0 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) zf-CCCH_4 PF18044.1 EGG03594.1 - 1.8 8.5 10.1 3 7.8 10.1 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 EGG03594.1 - 2.5 8.1 8.2 4.3 7.4 8.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Trehalase PF01204.18 EGG03595.1 - 2.8e-86 290.4 0.2 6.4e-73 246.3 0.0 2.4 2 1 0 2 2 2 2 Trehalase GDE_C PF06202.14 EGG03595.1 - 0.00017 20.6 0.1 0.0023 17.0 0.0 2.0 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Ribosomal_L22e PF01776.17 EGG03596.1 - 8.2e-43 145.2 0.3 1e-42 144.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Pro_isomerase PF00160.21 EGG03600.1 - 4.8e-45 153.7 0.1 5.4e-45 153.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Adaptin_N PF01602.20 EGG03601.1 - 3.1e-94 316.4 5.5 4.2e-94 316.0 5.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EGG03601.1 - 3.6e-59 198.7 0.4 8.4e-59 197.5 0.4 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EGG03601.1 - 2.1e-58 195.9 0.1 6.8e-58 194.2 0.0 2.0 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EGG03601.1 - 2.6e-09 37.3 7.5 0.00058 19.9 0.0 3.6 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGG03601.1 - 1e-07 32.2 0.4 0.15 12.5 0.3 4.6 1 1 3 5 5 5 3 HEAT repeats HEAT PF02985.22 EGG03601.1 - 7.1e-07 28.9 1.6 0.12 12.7 0.0 4.9 5 0 0 5 5 5 2 HEAT repeat DUF5578 PF17741.1 EGG03601.1 - 5.1e-05 22.8 4.6 0.0096 15.4 1.1 2.7 1 1 1 2 2 2 2 Family of unknown function (DUF5578) PatG_C PF18065.1 EGG03601.1 - 0.0035 17.3 0.6 0.42 10.6 0.2 2.7 2 0 0 2 2 2 1 PatG C-terminal MMS22L_C PF14911.6 EGG03601.1 - 0.58 9.2 7.7 2.4 7.1 0.1 3.5 2 2 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal Alpha_kinase PF02816.18 EGG03602.1 - 5.1e-09 36.5 0.1 8.2e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family RecQ_Zn_bind PF16124.5 EGG03602.1 - 0.15 12.8 0.8 2.5 8.9 0.1 2.6 2 0 0 2 2 2 0 RecQ zinc-binding DASH_Ask1 PF08655.10 EGG03603.1 - 9.4e-26 89.5 0.0 1.9e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 FAD_binding_4 PF01565.23 EGG03604.1 - 3.4e-28 98.1 1.7 5.8e-28 97.4 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGG03604.1 - 2.4e-13 49.9 0.9 4.6e-13 49.1 0.9 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EGG03604.1 - 0.011 15.1 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.23 EGG03606.1 - 2e-27 95.7 2.5 2.6e-27 95.3 2.5 1.1 1 0 0 1 1 1 1 FAD binding domain Cnd1_N PF12922.7 EGG03608.1 - 3.3e-47 160.4 2.7 3.3e-47 160.4 2.7 2.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term DUF3811 PF11656.8 EGG03608.1 - 0.013 15.8 0.6 0.029 14.8 0.6 1.5 1 0 0 1 1 1 0 YjbD family (DUF3811) Cnd1 PF12717.7 EGG03609.1 - 1.4e-35 122.7 0.4 3e-35 121.6 0.4 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 EGG03609.1 - 1.1e-06 28.0 1.0 6.8e-06 25.5 0.8 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 EGG03609.1 - 0.0072 16.8 0.0 2.1 8.9 0.0 3.4 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 EGG03609.1 - 0.048 13.9 0.0 24 5.5 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat FAD_binding_4 PF01565.23 EGG03610.1 - 5.9e-28 97.4 2.8 1.2e-27 96.4 2.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGG03610.1 - 2.5e-08 33.9 1.4 9.6e-08 32.0 1.4 2.0 1 1 0 1 1 1 1 Berberine and berberine like putAbiC PF16872.5 EGG03610.1 - 0.1 13.3 0.0 0.21 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative phage abortive infection protein FAD_binding_4 PF01565.23 EGG03611.1 - 5.3e-28 97.5 4.5 1.1e-27 96.5 3.1 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EGG03611.1 - 1.1e-13 51.0 1.2 2.2e-13 50.1 1.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EGG03611.1 - 0.011 15.2 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.23 EGG03612.1 - 8.2e-30 103.4 2.7 1.3e-29 102.7 2.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGG03612.1 - 8.9e-14 51.3 1.4 1.8e-13 50.4 1.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EGG03612.1 - 0.011 15.2 0.2 0.014 14.8 0.2 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding SR-25 PF10500.9 EGG03613.1 - 0.68 9.5 25.6 0.47 10.0 18.3 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein KDZ PF18758.1 EGG03615.1 - 1.6e-29 103.1 0.0 2.2e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGG03615.1 - 1.7e-23 82.8 0.2 3e-23 81.9 0.2 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG03615.1 - 1.8e-07 31.2 0.0 3.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG03615.1 - 0.17 11.8 0.4 0.54 10.1 0.2 2.0 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases Aldedh PF00171.22 EGG03616.1 - 1.3e-20 73.4 0.9 2.3e-15 56.1 0.2 2.1 1 1 0 2 2 2 2 Aldehyde dehydrogenase family PrpR_N PF06506.11 EGG03616.1 - 0.018 14.6 0.2 0.52 9.9 0.0 2.7 3 0 0 3 3 3 0 Propionate catabolism activator DUF1819 PF08849.11 EGG03616.1 - 0.025 14.4 0.2 0.069 12.9 0.2 1.7 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) DUF1699 PF08004.11 EGG03616.1 - 0.041 13.6 0.2 3.9 7.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) PIG-F PF06699.11 EGG03617.1 - 4e-38 131.4 2.5 8.8e-38 130.3 2.5 1.6 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F BAP PF06639.11 EGG03617.1 - 0.0057 17.0 1.3 0.0057 17.0 1.3 1.9 2 0 0 2 2 2 1 Basal layer antifungal peptide (BAP) Cation_ATPase_C PF00689.21 EGG03617.1 - 0.006 16.3 2.1 0.006 16.3 2.1 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus DUF2530 PF10745.9 EGG03617.1 - 0.15 12.3 3.8 0.38 11.0 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) SSP160 PF06933.11 EGG03617.1 - 10 4.2 11.0 17 3.4 11.0 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Fip1 PF05182.13 EGG03618.1 - 1.3e-15 56.6 3.3 2.3e-15 55.8 3.3 1.5 1 0 0 1 1 1 1 Fip1 motif TRI12 PF06609.13 EGG03619.1 - 0.13 10.6 0.1 0.15 10.5 0.1 1.0 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF5077 PF16871.5 EGG03620.1 - 0.11 12.4 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5077) NUDIX PF00293.28 EGG03621.1 - 3.7e-10 40.0 0.0 8.4e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain Phage_P2_GpE PF06528.12 EGG03621.1 - 0.04 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Phage P2 GpE GPR_Gpa2_C PF11970.8 EGG03621.1 - 0.28 11.3 1.8 0.7 10.0 1.8 1.7 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term p450 PF00067.22 EGG03624.1 - 1.6e-55 188.7 0.0 2.3e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BCS1_N PF08740.11 EGG03625.1 - 3.4e-50 170.6 1.3 4.6e-50 170.2 1.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGG03625.1 - 3.1e-19 69.7 0.0 5.5e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG03625.1 - 0.0062 16.9 0.0 0.033 14.6 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EGG03625.1 - 0.019 14.7 0.0 0.059 13.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 EGG03625.1 - 0.02 14.1 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EGG03625.1 - 0.023 15.3 0.0 0.046 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGG03625.1 - 0.027 14.9 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 EGG03625.1 - 0.036 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGG03625.1 - 0.066 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGG03625.1 - 0.069 12.7 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGG03625.1 - 0.087 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region PPV_E1_C PF00519.17 EGG03625.1 - 0.13 11.1 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase AAA_5 PF07728.14 EGG03625.1 - 0.14 12.2 0.0 0.38 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PH_TFIIH PF08567.11 EGG03625.1 - 0.16 12.3 0.3 0.4 11.0 0.1 1.8 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain TMEM135_C_rich PF15982.5 EGG03626.1 - 0.0093 16.6 0.1 0.27 11.9 0.1 2.5 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 MFS_1 PF07690.16 EGG03627.1 - 1e-12 47.7 24.2 1.9e-12 46.8 24.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily CagA PF03507.13 EGG03629.1 - 0.068 13.1 0.0 0.1 12.5 0.0 1.3 1 1 0 1 1 1 0 CagA exotoxin Rad51 PF08423.11 EGG03630.1 - 5.3e-10 39.0 0.0 5.7e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.6 EGG03630.1 - 0.0052 16.4 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 EGG03630.1 - 0.074 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF3195 PF11424.8 EGG03631.1 - 0.1 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGG03631.1 - 0.15 11.0 0.4 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 NUC194 domain DUF2170 PF09938.9 EGG03631.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) HAV_VP PF12944.7 EGG03634.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Hepatitis A virus viral protein VP DS PF01916.17 EGG03635.1 - 0.23 10.6 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase DUF4354 PF14263.6 EGG03644.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) DUF4380 PF14315.6 EGG03647.1 - 0.025 13.5 0.0 0.026 13.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) PUF PF00806.19 EGG03657.1 - 4.9e-09 35.4 0.0 0.0094 15.6 0.0 5.2 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat FxsA PF04186.13 EGG03657.1 - 0.095 12.8 0.0 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein PPP1R35_C PF15503.6 EGG03657.1 - 1.8 8.3 5.6 0.81 9.5 0.9 2.4 2 0 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus VTC PF09359.10 EGG03659.1 - 1.8e-90 303.1 0.1 3.4e-90 302.2 0.1 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 EGG03659.1 - 1.4e-15 58.2 27.2 3.4e-07 30.5 0.7 4.6 2 2 2 4 4 4 3 SPX domain DUF202 PF02656.15 EGG03659.1 - 7.9e-12 45.5 5.7 1.6e-11 44.5 5.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Mrpl_C PF18502.1 EGG03659.1 - 0.047 14.0 2.0 0.36 11.1 0.5 2.5 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain PAPA-1 PF04795.12 EGG03659.1 - 0.23 12.3 1.8 0.62 10.9 0.1 2.7 2 0 0 2 2 2 0 PAPA-1-like conserved region Hist_deacetyl PF00850.19 EGG03660.1 - 7e-85 285.2 0.0 1.1e-84 284.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 EGG03660.1 - 3.4e-22 78.8 0.0 4.9e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain CTU2 PF10288.9 EGG03662.1 - 1.8e-19 70.1 0.2 3.8e-19 69.0 0.2 1.6 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 JHD PF17811.1 EGG03663.1 - 2.7e-10 40.7 0.3 4.8e-10 39.9 0.3 1.4 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 EGG03663.1 - 2.6e-08 34.3 1.2 1.5e-06 28.6 1.2 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGG03663.1 - 5e-05 23.1 0.6 0.00099 18.9 0.1 2.5 1 1 0 2 2 2 1 Cupin-like domain PHB_acc_N PF07879.11 EGG03663.1 - 0.025 14.7 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain ArfGap PF01412.18 EGG03664.1 - 8.6e-32 109.7 0.6 2.1e-31 108.4 0.6 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Peptidase_S30 PF01577.16 EGG03664.1 - 0.053 13.1 1.1 0.1 12.2 1.1 1.4 1 0 0 1 1 1 0 Potyvirus P1 protease DZR PF12773.7 EGG03664.1 - 0.18 11.9 0.2 0.35 10.9 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Glyco_hydro_47 PF01532.20 EGG03665.1 - 5e-110 368.5 0.5 4.3e-56 190.7 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 DUF1057 PF06342.12 EGG03668.1 - 0.028 13.5 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) MBOAT_2 PF13813.6 EGG03669.1 - 0.00037 20.7 2.0 0.002 18.3 2.0 2.3 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family Trypan_PARP PF05887.11 EGG03670.1 - 0.00045 20.2 10.6 0.0009 19.2 10.6 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) WBS_methylT PF12589.8 EGG03670.1 - 0.77 10.6 4.7 6.2 7.7 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome She9_MDM33 PF05546.11 EGG03670.1 - 1.5 8.6 7.2 0.38 10.5 4.1 1.5 2 0 0 2 2 2 0 She9 / Mdm33 family PEX11 PF05648.14 EGG03671.1 - 6.9e-17 61.7 3.2 7.9e-17 61.5 3.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ORC6 PF05460.13 EGG03672.1 - 0.78 9.0 10.7 1.5 8.0 10.7 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Apolipoprotein PF01442.18 EGG03674.1 - 0.0052 16.7 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EGG03674.1 - 0.011 15.7 2.6 0.025 14.6 2.6 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2130 PF09903.9 EGG03674.1 - 0.054 12.8 0.9 0.082 12.2 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) SF-assemblin PF06705.11 EGG03674.1 - 0.055 12.8 0.8 0.087 12.2 0.8 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin Transcrip_act PF04949.13 EGG03674.1 - 0.09 12.7 0.9 6.9 6.5 0.1 2.2 1 1 1 2 2 2 0 Transcriptional activator Fzo_mitofusin PF04799.13 EGG03674.1 - 0.11 12.1 0.6 0.22 11.0 0.6 1.5 1 0 0 1 1 1 0 fzo-like conserved region DUF1640 PF07798.11 EGG03674.1 - 0.14 12.2 3.0 0.3 11.1 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DASH_Dad1 PF08649.10 EGG03675.1 - 5e-18 65.0 1.7 5.7e-18 64.9 1.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Yos9_DD PF17880.1 EGG03675.1 - 0.09 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Yos9 dimerzation domain Thioredoxin PF00085.20 EGG03677.1 - 1.1e-22 79.9 0.1 1.5e-22 79.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EGG03677.1 - 6.5e-06 26.1 0.0 7.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 EGG03677.1 - 9.5e-06 26.0 0.1 0.00068 20.1 0.1 2.7 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGG03677.1 - 0.00016 22.0 0.0 0.00027 21.2 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EGG03677.1 - 0.00041 20.1 0.1 0.00094 18.9 0.1 1.6 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 EGG03677.1 - 0.0012 19.0 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EGG03677.1 - 0.0036 17.1 0.0 0.0053 16.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AAA_12 PF13087.6 EGG03679.1 - 3.1e-39 134.7 0.0 3.8e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGG03679.1 - 1.3e-07 31.7 0.3 2.1e-07 31.0 0.3 1.3 1 0 0 1 1 1 1 AAA domain FAD_binding_4 PF01565.23 EGG03680.1 - 9e-27 93.5 2.4 1.5e-26 92.8 2.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGG03680.1 - 2.1e-14 53.4 1.2 4e-14 52.5 1.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like eIF_4G1 PF12152.8 EGG03680.1 - 0.11 12.7 0.2 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4G1 EXOSC1 PF10447.9 EGG03681.1 - 2.7e-15 56.9 1.6 2.5e-12 47.4 0.1 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EGG03681.1 - 2e-05 24.3 0.5 0.00033 20.4 0.5 2.5 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Myb_DNA-bind_3 PF12776.7 EGG03683.1 - 2.3e-09 38.1 2.5 4.6e-09 37.1 2.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGG03683.1 - 1.1e-05 25.7 1.6 2.9e-05 24.4 1.6 1.8 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain API5 PF05918.11 EGG03685.1 - 0.53 9.0 5.7 0.55 9.0 5.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FAD_binding_4 PF01565.23 EGG03687.1 - 3.9e-24 85.0 3.8 8.8e-24 83.8 3.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGG03687.1 - 4e-12 46.0 1.2 6.9e-12 45.3 1.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EGG03687.1 - 0.0058 16.1 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding putAbiC PF16872.5 EGG03687.1 - 0.034 14.8 0.1 0.078 13.7 0.1 1.6 1 0 0 1 1 1 0 Putative phage abortive infection protein CxC5 PF18718.1 EGG03688.1 - 5.9e-32 110.2 5.7 1.1e-31 109.4 5.7 1.4 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG03688.1 - 1.6e-20 73.1 0.9 3.3e-20 72.1 0.9 1.5 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases Elong_Iki1 PF10483.9 EGG03690.1 - 3.3e-10 39.9 0.2 4e-10 39.7 0.2 1.3 1 1 0 1 1 1 1 Elongator subunit Iki1 AMP-binding PF00501.28 EGG03691.1 - 1.6e-27 96.2 0.0 3.9e-27 94.9 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme DUF3105 PF11303.8 EGG03691.1 - 0.00025 21.2 0.0 0.33 11.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3105) RNA_pol_Rpb5_C PF01191.19 EGG03691.1 - 0.083 12.8 0.1 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain PNK3P PF08645.11 EGG03692.1 - 7.2e-56 188.3 0.1 1.4e-55 187.4 0.1 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EGG03692.1 - 3e-19 69.6 0.0 2e-07 31.2 0.0 3.3 2 1 1 3 3 3 3 AAA domain TniB PF05621.11 EGG03692.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF705 PF05152.12 EGG03692.1 - 0.15 11.5 0.1 0.66 9.4 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF705) Glyco_hydro_35 PF01301.19 EGG03693.1 - 2e-76 257.6 0.3 3.8e-76 256.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EGG03693.1 - 3.2e-45 153.4 0.1 2.6e-27 95.7 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EGG03693.1 - 1.6e-18 67.2 1.1 2.8e-18 66.4 1.1 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EGG03693.1 - 8.9e-11 41.2 0.0 1.9e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 DUF1800 PF08811.11 EGG03693.1 - 0.17 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) SKI PF01202.22 EGG03696.1 - 6.8e-07 29.5 0.0 7.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 EGG03696.1 - 5.2e-06 26.7 0.0 5.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG03696.1 - 2.6e-05 24.8 0.0 2.6e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EGG03696.1 - 0.00032 20.7 0.0 0.00032 20.7 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EGG03696.1 - 0.00034 20.9 0.0 0.00034 20.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG03696.1 - 0.00039 20.9 0.0 0.00039 20.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 EGG03696.1 - 0.00047 20.1 0.0 0.00049 20.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.22 EGG03696.1 - 0.00054 20.3 0.0 0.00063 20.1 0.0 1.1 1 0 0 1 1 1 1 RNA helicase Cytidylate_kin PF02224.18 EGG03696.1 - 0.00066 19.5 0.0 0.00066 19.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 EGG03696.1 - 0.00087 19.7 0.0 0.001 19.5 0.0 1.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EGG03696.1 - 0.0015 18.3 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.6 EGG03696.1 - 0.0024 18.0 0.0 0.0026 17.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase-like family Hpr_kinase_C PF07475.12 EGG03696.1 - 0.0056 16.2 0.0 0.0056 16.2 0.0 1.1 1 0 0 1 1 1 1 HPr Serine kinase C-terminal domain AAA_14 PF13173.6 EGG03696.1 - 0.0074 16.3 0.0 0.0086 16.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGG03696.1 - 0.0089 16.5 0.0 0.0089 16.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EGG03696.1 - 0.0092 16.0 0.0 0.0092 16.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 EGG03696.1 - 0.0099 15.2 0.0 0.0099 15.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IPT PF01745.16 EGG03696.1 - 0.01 15.3 0.0 0.01 15.2 0.0 1.0 1 0 0 1 1 1 0 Isopentenyl transferase AAA_5 PF07728.14 EGG03696.1 - 0.012 15.7 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PRK PF00485.18 EGG03696.1 - 0.013 15.2 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 EGG03696.1 - 0.017 15.0 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EGG03696.1 - 0.021 15.3 0.1 0.024 15.1 0.1 1.3 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EGG03696.1 - 0.024 14.9 0.0 0.024 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 EGG03696.1 - 0.036 13.5 0.5 0.044 13.2 0.4 1.3 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_25 PF13481.6 EGG03696.1 - 0.037 13.6 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 EGG03696.1 - 0.037 13.7 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Dephospho-CoA kinase tRNA_lig_kinase PF08303.11 EGG03696.1 - 0.041 14.0 0.0 0.042 14.0 0.0 1.1 1 0 0 1 1 1 0 tRNA ligase kinase domain RsgA_GTPase PF03193.16 EGG03696.1 - 0.049 13.5 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 EGG03696.1 - 0.05 13.3 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGG03696.1 - 0.093 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 EGG03696.1 - 0.14 11.3 0.3 0.24 10.5 0.2 1.5 1 1 0 1 1 1 0 NB-ARC domain dNK PF01712.19 EGG03696.1 - 0.17 11.7 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Deoxynucleoside kinase Ploopntkinase3 PF18751.1 EGG03696.1 - 0.2 11.5 0.0 0.2 11.5 0.0 1.0 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 OHCU_decarbox PF09349.10 EGG03697.1 - 8.3e-30 104.3 0.0 9.5e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase UQ_con PF00179.26 EGG03698.1 - 4.2e-42 143.1 0.0 5.3e-42 142.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EGG03698.1 - 2.9e-13 49.4 0.0 4.3e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_2 PF08587.11 EGG03698.1 - 0.087 12.9 0.2 0.36 11.0 0.0 2.1 3 0 0 3 3 3 0 Ubiquitin associated domain (UBA) Calsarcin PF05556.11 EGG03698.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) UBA PF00627.31 EGG03698.1 - 0.16 11.9 0.1 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 UBA/TS-N domain F-box-like PF12937.7 EGG03701.1 - 0.026 14.4 0.2 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EGG03702.1 - 0.025 14.5 0.0 0.079 12.9 0.0 1.9 1 1 0 1 1 1 0 F-box domain BRO1 PF03097.18 EGG03704.1 - 3e-109 365.4 0.6 3e-109 365.4 0.6 2.1 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EGG03704.1 - 9.1e-58 195.9 14.6 1.5e-57 195.2 14.6 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Not1 PF04054.15 EGG03704.1 - 0.52 9.2 2.8 0.48 9.3 0.0 2.2 2 0 0 2 2 2 0 CCR4-Not complex component, Not1 DUF3958 PF13125.6 EGG03704.1 - 2.2 8.5 6.1 1.4 9.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) Yip1 PF04893.17 EGG03705.1 - 5.4e-08 32.8 15.5 1.5e-07 31.3 15.5 1.7 1 1 0 1 1 1 1 Yip1 domain CAAD PF14159.6 EGG03705.1 - 0.026 14.4 1.0 0.026 14.4 1.0 2.1 1 1 1 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase YIF1 PF03878.15 EGG03705.1 - 0.12 11.8 4.5 2.3 7.7 4.5 2.2 1 1 0 1 1 1 0 YIF1 DUF202 PF02656.15 EGG03705.1 - 5.8 7.4 9.6 6.2 7.4 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) GDP_Man_Dehyd PF16363.5 EGG03706.1 - 2.9e-49 168.3 0.0 1.5e-48 165.9 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG03706.1 - 7.7e-42 143.4 0.0 9.4e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGG03706.1 - 1.8e-14 53.6 0.0 1.6e-13 50.5 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGG03706.1 - 2.1e-14 53.2 0.0 5.9e-14 51.7 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGG03706.1 - 1.4e-12 47.4 0.0 2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGG03706.1 - 8.3e-06 25.2 0.0 2.1e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EGG03706.1 - 0.00024 21.1 0.0 0.00055 19.9 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 EGG03706.1 - 0.0024 17.8 0.0 0.0057 16.6 0.0 1.6 1 1 0 1 1 1 1 KR domain PBP PF01161.20 EGG03707.1 - 3.1e-15 56.7 0.1 2.2e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylethanolamine-binding protein PBP PF01161.20 EGG03708.1 - 5.8e-05 23.4 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3640 PF12342.8 EGG03709.1 - 0.028 14.1 5.0 1 9.2 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3640) Pro_isomerase PF00160.21 EGG03710.1 - 4.1e-50 170.1 0.3 4.9e-50 169.9 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Polysacc_deac_1 PF01522.21 EGG03711.1 - 2.1e-32 111.7 0.0 4.9e-32 110.4 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGG03711.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 EGG03711.1 - 0.12 12.0 0.3 0.2 11.3 0.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Toxin_31 PF08119.11 EGG03712.1 - 0.046 13.5 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 Scorpion acidic alpha-KTx toxin family zf-C3HC4_3 PF13920.6 EGG03713.1 - 2.9e-08 33.4 5.2 5.7e-08 32.5 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 EGG03713.1 - 3.7e-08 33.1 2.5 3.7e-08 33.1 2.5 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 EGG03713.1 - 5.3e-06 26.3 9.4 9.7e-06 25.4 9.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG03713.1 - 7.7e-06 25.8 10.2 1.5e-05 24.9 10.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG03713.1 - 1.4e-05 24.8 9.8 2.8e-05 23.8 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG03713.1 - 3.7e-05 24.0 8.1 7.3e-05 23.0 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGG03713.1 - 5.8e-05 22.9 10.1 0.00011 22.0 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGG03713.1 - 6.9e-05 22.9 4.6 6.9e-05 22.9 4.6 1.7 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf_CCCH_4 PF18345.1 EGG03713.1 - 0.00023 21.1 4.6 0.00023 21.1 4.6 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGG03713.1 - 0.0026 17.5 3.4 0.0026 17.5 3.4 2.3 2 0 0 2 2 1 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 EGG03713.1 - 0.0039 17.3 8.0 0.0039 17.3 8.0 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EGG03713.1 - 0.015 15.1 3.7 0.022 14.6 3.7 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RanBP PF00641.18 EGG03713.1 - 0.017 14.4 1.6 0.017 14.4 1.6 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Prok-RING_4 PF14447.6 EGG03713.1 - 0.042 13.7 6.7 0.087 12.7 6.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CHDCT2 PF08074.11 EGG03714.1 - 0.059 13.6 0.2 0.061 13.5 0.2 1.1 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Peptidase_C78 PF07910.13 EGG03715.1 - 3.1e-44 151.0 0.1 2.8e-42 144.6 0.1 2.3 1 1 0 1 1 1 1 Peptidase family C78 Pyr_redox_3 PF13738.6 EGG03716.1 - 1.5e-19 70.4 0.0 1.2e-15 57.6 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EGG03716.1 - 5.1e-15 54.9 0.0 3.7e-13 48.8 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGG03716.1 - 2e-12 47.0 0.0 1.5e-06 27.7 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGG03716.1 - 4.2e-10 39.3 0.0 2.5e-06 26.9 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EGG03716.1 - 1e-05 24.5 0.0 0.00029 19.6 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EGG03716.1 - 1.1e-05 24.9 0.0 4.9e-05 22.7 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 EGG03716.1 - 4.6e-05 23.9 0.2 0.22 12.1 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG03716.1 - 0.0001 22.4 0.0 0.00029 21.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG03716.1 - 0.00016 21.4 0.0 0.3 10.6 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EGG03716.1 - 0.00028 21.0 0.0 0.1 12.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EGG03716.1 - 0.0017 17.5 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EGG03716.1 - 0.0022 17.1 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EGG03716.1 - 0.0026 17.8 0.0 0.52 10.3 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EGG03716.1 - 0.003 16.7 0.0 0.074 12.1 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Amino_oxidase PF01593.24 EGG03716.1 - 0.02 14.2 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.19 EGG03716.1 - 0.031 13.7 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EGG03716.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EGG03716.1 - 0.17 12.2 0.0 0.46 10.8 0.0 1.7 2 0 0 2 2 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 EGG03716.1 - 0.2 10.9 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain COesterase PF00135.28 EGG03717.1 - 6.2e-85 286.0 0.0 9.2e-85 285.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EGG03717.1 - 0.0017 17.9 0.5 0.0029 17.1 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGG03717.1 - 0.002 18.0 0.2 0.0076 16.1 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pkinase PF00069.25 EGG03720.1 - 1.6e-37 129.4 0.0 2.1e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG03720.1 - 3.5e-27 95.3 0.0 4.4e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG03720.1 - 0.0025 17.8 0.0 0.35 10.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG03720.1 - 0.0028 17.0 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG03720.1 - 0.004 16.5 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGG03720.1 - 0.097 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EGG03720.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4218 PF13960.6 EGG03721.1 - 0.037 13.6 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) tRNA-synt_His PF13393.6 EGG03722.1 - 1.7e-40 139.3 0.0 1.4e-34 119.7 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EGG03722.1 - 4.3e-10 39.6 0.1 1.9e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.20 EGG03722.1 - 1.4e-07 31.5 0.2 5.8e-07 29.6 0.2 2.1 1 0 0 1 1 1 1 WHEP-TRS domain HGTP_anticodon2 PF12745.7 EGG03722.1 - 5.8e-07 29.3 0.3 5.8e-07 29.3 0.3 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 EGG03722.1 - 0.0005 19.3 0.2 0.0032 16.6 0.1 2.1 1 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Glyco_hydro_16 PF00722.21 EGG03724.1 - 0.075 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 eIF3m_C_helix PF18005.1 EGG03726.1 - 2.2e-05 24.0 0.0 4.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix XAP5 PF04921.14 EGG03727.1 - 1.5e-82 277.2 5.6 1.5e-82 277.2 5.6 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF5627 PF18620.1 EGG03727.1 - 0.009 15.9 0.8 0.019 14.9 0.7 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF5627) Mem_trans PF03547.18 EGG03727.1 - 0.45 8.8 3.3 0.66 8.3 3.3 1.2 1 0 0 1 1 1 0 Membrane transport protein Seipin PF06775.14 EGG03728.1 - 4.3e-52 177.1 0.2 5.6e-52 176.7 0.2 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF1199 PF06712.11 EGG03728.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) HIG_1_N PF04588.13 EGG03729.1 - 1.4e-05 25.2 1.6 1.4e-05 25.2 1.6 2.5 3 0 0 3 3 3 1 Hypoxia induced protein conserved region WYL_3 PF18488.1 EGG03729.1 - 0.13 12.7 0.1 5 7.6 0.0 2.4 2 0 0 2 2 2 0 WYL domain TCTP PF00838.17 EGG03731.1 - 7.7e-72 241.0 1.3 8.6e-72 240.9 1.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein MDM31_MDM32 PF08118.11 EGG03733.1 - 1.3e-161 538.8 0.0 2.2e-161 538.1 0.0 1.3 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins MASE1 PF05231.14 EGG03733.1 - 0.014 14.5 0.5 0.022 13.9 0.5 1.2 1 0 0 1 1 1 0 MASE1 UDPGP PF01704.18 EGG03734.1 - 6.6e-201 667.3 0.1 7.6e-201 667.1 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase TPT PF03151.16 EGG03735.1 - 2.6e-24 86.1 26.5 3.3e-24 85.7 26.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGG03735.1 - 3.7e-12 46.6 42.9 3.7e-07 30.4 17.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family FixS PF03597.15 EGG03735.1 - 0.35 10.6 0.1 0.35 10.6 0.1 3.3 5 0 0 5 5 5 0 Cytochrome oxidase maturation protein cbb3-type DUF3995 PF13160.6 EGG03735.1 - 6.1 7.2 10.3 0.44 10.9 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) Rhodanese PF00581.20 EGG03740.1 - 0.016 15.7 0.0 0.057 13.9 0.0 1.9 1 1 0 1 1 1 0 Rhodanese-like domain GBP PF02263.19 EGG03740.1 - 0.087 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain zf-C2H2 PF00096.26 EGG03742.1 - 8.4e-05 22.8 9.7 0.019 15.4 0.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG03742.1 - 0.0056 17.4 9.8 0.83 10.7 2.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGG03742.1 - 0.009 16.4 6.1 0.039 14.4 6.1 2.2 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGG03742.1 - 2.5 8.2 12.1 0.067 13.2 4.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger BSD PF03909.17 EGG03743.1 - 1.3e-10 41.1 0.2 1.3e-10 41.1 0.2 2.3 3 0 0 3 3 3 1 BSD domain B2 PF11473.8 EGG03743.1 - 0.072 12.9 0.1 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA binding protein B2 Ribosomal_S13 PF00416.22 EGG03743.1 - 4.9 7.6 6.2 22 5.5 0.5 3.0 3 0 0 3 3 3 0 Ribosomal protein S13/S18 UME PF08064.13 EGG03745.1 - 0.14 12.0 0.1 0.2 11.6 0.1 1.2 1 0 0 1 1 1 0 UME (NUC010) domain ABC_tran_CTD PF16326.5 EGG03745.1 - 0.18 12.1 0.8 0.39 11.0 0.8 1.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain CxC1 PF18802.1 EGG03746.1 - 1.3e-23 83.1 0.2 3.5e-23 81.7 0.2 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG03746.1 - 3.7e-05 23.8 0.0 9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG03746.1 - 0.00045 20.0 0.0 0.0017 18.2 0.0 2.1 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases DDE_Tnp_1 PF01609.21 EGG03747.1 - 0.04 13.5 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain CxC1 PF18802.1 EGG03749.1 - 4.8e-35 119.9 0.4 7.7e-35 119.2 0.4 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG03749.1 - 1.5e-05 25.1 0.1 2.5e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG03749.1 - 0.0006 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGG03749.1 - 0.048 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase DUF1708 PF08101.11 EGG03753.1 - 1.5e-23 83.7 0.4 1.3e-20 74.0 0.1 3.1 2 2 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 EGG03753.1 - 9.8e-08 32.0 0.0 1.5e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain CxC5 PF18718.1 EGG03754.1 - 5.7e-29 100.6 7.6 9.2e-29 99.9 7.6 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG03754.1 - 0.0027 17.9 0.0 0.0027 17.9 0.0 2.1 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases CsbD PF05532.12 EGG03755.1 - 0.1 12.5 6.1 0.63 10.0 0.4 3.1 2 1 1 3 3 3 0 CsbD-like SVIP PF15811.5 EGG03755.1 - 0.19 12.2 4.8 0.69 10.4 4.8 1.9 1 1 0 1 1 1 0 Small VCP/p97-interacting protein DUF883 PF05957.13 EGG03755.1 - 0.62 10.7 6.5 1.8 9.2 6.5 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) GDWWSH PF15667.5 EGG03755.1 - 0.79 9.1 7.7 0.89 8.9 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function with motif GDWWSH YtxH PF12732.7 EGG03755.1 - 4.1 8.0 11.3 75 4.0 11.3 2.1 1 1 0 1 1 1 0 YtxH-like protein Aminotran_1_2 PF00155.21 EGG03756.1 - 1.1e-57 195.9 0.0 1.2e-57 195.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGG03756.1 - 5.4e-07 29.2 0.0 1.5e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EGG03756.1 - 3.1e-05 22.7 0.0 8.2e-05 21.3 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGG03756.1 - 0.0018 17.6 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2240 PF09999.9 EGG03756.1 - 0.016 14.8 0.1 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2240) Aminotran_5 PF00266.19 EGG03756.1 - 0.039 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V SUI1 PF01253.22 EGG03758.1 - 6.8e-24 84.2 0.8 1.4e-23 83.2 0.8 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cdh1_DBD_1 PF18196.1 EGG03758.1 - 0.1 12.9 6.4 0.41 11.0 4.3 2.2 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DUF2121 PF09894.9 EGG03758.1 - 1.3 8.5 9.3 3.7 7.0 9.3 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) RAP1 PF07218.11 EGG03759.1 - 0.00059 18.3 10.8 0.00083 17.8 10.8 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Syntaxin-6_N PF09177.11 EGG03759.1 - 0.0043 17.6 3.7 0.01 16.4 3.7 1.6 1 0 0 1 1 1 1 Syntaxin 6, N-terminal CASP_C PF08172.12 EGG03759.1 - 0.019 14.3 7.7 0.034 13.5 7.7 1.4 1 0 0 1 1 1 0 CASP C terminal Tmemb_cc2 PF10267.9 EGG03759.1 - 0.34 10.0 8.3 0.54 9.3 8.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein FapA PF03961.13 EGG03759.1 - 0.36 9.4 4.6 0.52 8.8 4.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Neur_chan_memb PF02932.16 EGG03759.1 - 2.2 8.3 4.6 4.5 7.3 4.6 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.9 EGG03759.1 - 3.4 6.1 8.6 5.2 5.5 8.6 1.2 1 0 0 1 1 1 0 Macoilin family Clr5 PF14420.6 EGG03761.1 - 0.00022 21.4 0.0 0.29 11.4 0.0 2.4 2 0 0 2 2 2 2 Clr5 domain Rhomboid PF01694.22 EGG03762.1 - 9.8e-07 28.9 1.4 2e-06 27.9 1.4 1.5 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 EGG03762.1 - 0.0075 16.8 3.6 0.048 14.2 2.5 2.4 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Far-17a_AIG1 PF04750.14 EGG03763.1 - 3.6e-07 29.7 6.2 3.9e-07 29.6 6.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Prenyltrans PF00432.21 EGG03764.1 - 8.5e-27 92.6 7.3 3.4e-07 29.9 0.0 5.4 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Sec6 PF06046.13 EGG03764.1 - 0.056 11.8 0.0 0.19 10.0 0.0 1.7 2 0 0 2 2 2 0 Exocyst complex component Sec6 SQHop_cyclase_N PF13249.6 EGG03764.1 - 0.13 11.4 0.0 5.8 5.9 0.0 2.2 1 1 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain GSH_synth_ATP PF03917.17 EGG03765.1 - 6.4e-126 420.1 0.0 7.3e-126 419.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EGG03765.1 - 8.2e-28 96.9 0.0 1.4e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase TFIIE_beta PF02186.15 EGG03765.1 - 0.12 12.6 0.2 0.93 9.8 0.1 2.3 2 0 0 2 2 2 0 TFIIE beta subunit core domain Inh PF02974.14 EGG03767.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Protease inhibitor Inh SprT-like PF10263.9 EGG03768.1 - 2.2e-17 63.0 0.0 5.7e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 SprT-like family MBOAT_2 PF13813.6 EGG03769.1 - 9.1e-07 29.1 10.2 1.3e-06 28.6 5.4 3.0 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family MAPEG PF01124.18 EGG03770.1 - 3.3e-23 82.0 1.4 3.8e-23 81.8 1.4 1.1 1 0 0 1 1 1 1 MAPEG family Gar1 PF04410.14 EGG03774.1 - 1.1e-33 116.2 0.1 1.1e-33 116.2 0.1 3.1 4 0 0 4 4 4 1 Gar1/Naf1 RNA binding region ETC_C1_NDUFA4 PF04800.12 EGG03775.1 - 1e-35 121.8 0.5 1.1e-35 121.7 0.5 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region Pkinase PF00069.25 EGG03778.1 - 1.5e-68 231.1 0.0 1.8e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG03778.1 - 3.2e-34 118.4 0.0 4.3e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG03778.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CEND1 PF15677.5 EGG03778.1 - 9.7 6.7 9.0 17 6.0 9.0 1.3 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 GYF PF02213.16 EGG03780.1 - 5.2e-18 64.5 0.2 1e-17 63.5 0.2 1.5 1 0 0 1 1 1 1 GYF domain Bombesin PF02044.17 EGG03781.1 - 0.089 12.9 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 Bombesin-like peptide DUF1906 PF08924.11 EGG03782.1 - 0.023 14.8 0.4 0.033 14.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) DUF2889 PF11136.8 EGG03782.1 - 0.026 14.9 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2889) ATP-grasp_2 PF08442.10 EGG03783.1 - 2.7e-66 223.0 0.5 4.1e-66 222.4 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EGG03783.1 - 6.9e-24 84.4 2.1 1.1e-23 83.8 0.9 1.9 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 EGG03783.1 - 3.2e-11 43.1 0.4 9.3e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EGG03783.1 - 3e-05 23.9 0.5 0.00011 22.0 0.0 2.2 2 1 1 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 EGG03783.1 - 0.00012 21.6 0.2 0.00032 20.3 0.1 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EGG03783.1 - 0.0074 15.9 0.0 0.021 14.4 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EGG03783.1 - 0.086 12.4 0.0 0.37 10.4 0.0 2.1 1 1 1 2 2 2 0 RimK-like ATP-grasp domain GMC_oxred_N PF00732.19 EGG03784.1 - 3.3e-50 171.1 0.4 5.3e-50 170.5 0.4 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGG03784.1 - 1.7e-24 87.0 0.0 3.4e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EGG03784.1 - 4e-06 26.9 0.2 5.5e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGG03784.1 - 6.1e-05 22.3 0.0 0.0003 20.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EGG03784.1 - 0.00025 20.7 0.3 0.0015 18.2 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG03784.1 - 0.00028 20.2 0.1 0.00054 19.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGG03784.1 - 0.00043 19.6 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GDI PF00996.18 EGG03784.1 - 0.00062 18.4 0.2 0.0015 17.1 0.1 1.6 2 0 0 2 2 2 1 GDP dissociation inhibitor HI0933_like PF03486.14 EGG03784.1 - 0.00071 18.4 0.3 0.0079 14.9 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EGG03784.1 - 0.011 15.0 0.1 0.037 13.3 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pep1_7 PF17232.2 EGG03784.1 - 0.046 14.2 1.6 0.14 12.7 1.6 1.8 1 0 0 1 1 1 0 Elicitor peptide 1-7 ApbA PF02558.16 EGG03784.1 - 0.047 13.3 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EGG03784.1 - 0.061 12.2 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EGG03784.1 - 0.062 12.5 0.2 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGG03784.1 - 0.071 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EGG03784.1 - 0.089 13.4 0.1 0.24 12.0 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EGG03784.1 - 0.089 13.1 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EGG03784.1 - 0.15 12.3 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Glyco_hydro2_C5 PF18565.1 EGG03784.1 - 0.16 11.8 0.0 0.6 10.0 0.0 1.9 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 COXG PF06240.13 EGG03784.1 - 0.2 11.4 0.5 0.38 10.5 0.1 1.7 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) Pkinase PF00069.25 EGG03785.1 - 4.9e-58 196.6 0.0 5.6e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG03785.1 - 2.6e-43 148.2 0.0 3.3e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG03785.1 - 6.2e-05 22.5 0.0 0.00013 21.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGG03785.1 - 0.013 14.5 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGG03785.1 - 0.014 15.4 0.7 0.13 12.2 0.2 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGG03785.1 - 0.016 14.3 0.1 0.024 13.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EGG03785.1 - 0.026 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGG03785.1 - 0.042 12.6 0.0 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EGG03785.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Band_3_cyto PF07565.13 EGG03786.1 - 0.0021 17.9 2.6 0.0021 17.9 2.6 1.6 2 0 0 2 2 2 1 Band 3 cytoplasmic domain SKA1 PF07160.12 EGG03786.1 - 4.8 7.0 12.8 0.27 11.0 7.3 1.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Ndc1_Nup PF09531.10 EGG03786.1 - 5.5 5.6 5.8 7.5 5.1 5.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sad1_UNC PF07738.13 EGG03787.1 - 1.2e-22 80.4 0.0 1.6e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 EGG03787.1 - 0.0063 16.6 0.0 0.011 15.8 0.0 1.4 1 1 0 1 1 1 1 F5/8 type C domain MFS_1 PF07690.16 EGG03789.1 - 2.2e-16 59.7 40.5 8.9e-15 54.5 40.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGG03789.1 - 1.1e-13 50.6 18.7 1.4e-13 50.1 18.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 EGG03789.1 - 0.14 12.4 3.4 0.29 11.3 1.7 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 UQ_con PF00179.26 EGG03790.1 - 4.3e-12 45.9 0.0 1.2e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 EGG03790.1 - 1.6e-07 31.1 0.1 3.8e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain IBR PF01485.21 EGG03790.1 - 0.0083 16.3 2.2 0.018 15.3 2.2 1.5 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain FYVE PF01363.21 EGG03790.1 - 0.092 12.9 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger UAA PF08449.11 EGG03791.1 - 2e-49 168.4 12.5 3.1e-49 167.8 12.5 1.3 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EGG03791.1 - 5.5e-05 22.5 1.8 0.055 12.6 0.3 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 EGG03791.1 - 5.7e-05 23.3 24.5 0.00018 21.7 14.0 4.1 3 2 0 3 3 3 1 EamA-like transporter family Cation_ATPase_C PF00689.21 EGG03791.1 - 0.52 10.0 11.6 0.66 9.7 8.3 2.6 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus TMEM234 PF10639.9 EGG03791.1 - 1.7 8.7 7.1 7.7 6.6 0.9 3.0 3 0 0 3 3 3 0 Putative transmembrane family 234 NUDIX PF00293.28 EGG03792.1 - 0.0036 17.3 0.0 0.031 14.3 0.0 2.4 1 1 0 1 1 1 1 NUDIX domain Chlam_OMP PF01308.17 EGG03792.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlamydia major outer membrane protein UCH PF00443.29 EGG03793.1 - 1.7e-52 178.5 0.0 2.4e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG03793.1 - 4e-25 89.1 0.2 6.6e-25 88.4 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EGG03793.1 - 0.0038 16.7 4.9 0.12 11.8 4.9 2.9 1 1 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase ABC_tran PF00005.27 EGG03794.1 - 1.1e-40 139.3 0.0 1.8e-26 93.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGG03794.1 - 4.7e-38 131.4 23.0 4.1e-23 82.4 10.8 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 EGG03794.1 - 9.7e-09 35.0 0.0 0.009 15.5 2.7 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGG03794.1 - 3.5e-06 27.3 0.1 0.0024 18.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGG03794.1 - 2.3e-05 25.0 0.1 0.1 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGG03794.1 - 6.3e-05 22.6 0.1 0.57 10.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 EGG03794.1 - 0.00067 19.3 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGG03794.1 - 0.00078 19.9 0.0 0.069 13.5 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EGG03794.1 - 0.012 14.8 0.0 0.056 12.6 0.0 2.0 2 1 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 EGG03794.1 - 0.017 14.5 0.4 5 6.4 0.0 2.5 2 0 0 2 2 2 0 KaiC CcmD PF04995.14 EGG03794.1 - 0.035 14.2 1.2 0.14 12.2 1.2 2.1 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) T2SSE PF00437.20 EGG03794.1 - 0.057 12.5 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 EGG03794.1 - 0.47 10.3 2.5 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain SKG6 PF08693.10 EGG03794.1 - 0.95 8.9 4.2 0.27 10.7 0.1 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain GDPD PF03009.17 EGG03796.1 - 1.1e-32 113.9 0.0 2e-32 112.9 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EGG03796.1 - 0.0031 17.9 0.9 0.011 16.2 0.9 1.9 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family RPN7 PF10602.9 EGG03797.1 - 5.1e-36 124.0 1.4 9.4e-36 123.1 1.4 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGG03797.1 - 2.7e-09 37.5 0.2 1e-07 32.4 0.0 3.1 2 2 1 3 3 3 1 PCI domain TPR_2 PF07719.17 EGG03797.1 - 0.005 16.9 3.9 6.2 7.2 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG03797.1 - 1.9 8.9 6.3 0.43 10.9 0.7 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Nop14 PF04147.12 EGG03798.1 - 1.3e-260 867.4 13.8 1.5e-260 867.1 13.8 1.0 1 0 0 1 1 1 1 Nop14-like family Cyclophil_like2 PF18050.1 EGG03800.1 - 0.00087 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin-like family EXOSC1 PF10447.9 EGG03800.1 - 0.12 13.0 0.1 0.19 12.3 0.1 1.4 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 Ysc84 PF04366.12 EGG03801.1 - 8.9e-36 122.5 0.9 1.5e-35 121.7 0.9 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EGG03801.1 - 2.3e-13 49.5 0.2 6.1e-13 48.2 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG03801.1 - 1.5e-11 43.8 0.1 6.5e-10 38.5 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EGG03801.1 - 5.8e-10 38.9 0.0 1.7e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain DUF3886 PF13025.6 EGG03803.1 - 0.13 12.5 9.3 0.37 11.0 9.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) CxC5 PF18718.1 EGG03805.1 - 3.5e-09 36.8 0.4 5.2e-09 36.2 0.4 1.2 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases P22_Tail-4 PF11650.8 EGG03806.1 - 5.3 7.0 13.1 1.3 9.0 0.2 2.8 1 1 2 3 3 3 0 P22 tail accessory factor Cwf_Cwc_15 PF04889.12 EGG03807.1 - 3.3e-84 282.5 27.3 4.5e-84 282.0 27.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 EGG03807.1 - 0.017 13.7 28.2 0.022 13.4 28.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 EGG03807.1 - 0.53 8.5 19.4 0.63 8.3 19.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 EGG03807.1 - 1.9 7.5 20.1 12 4.9 19.9 1.9 1 1 0 1 1 1 0 Drosophila roughex protein DUF3678 PF12435.8 EGG03807.1 - 5.4 6.5 8.6 3.2 7.2 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) NOA36 PF06524.12 EGG03807.1 - 7.8 5.7 21.4 14 4.9 21.4 1.5 1 0 0 1 1 1 0 NOA36 protein OMPdecase PF00215.24 EGG03810.1 - 6.7e-08 32.4 0.1 7.7e-08 32.2 0.1 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Vac_Fusion PF02346.16 EGG03810.1 - 0.016 14.9 0.2 1.7 8.4 0.0 2.4 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 OMPdecase PF00215.24 EGG03811.1 - 6.4e-09 35.7 0.0 7.6e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family RhoGAP PF00620.27 EGG03813.1 - 3.7e-43 147.0 0.1 4e-43 146.9 0.1 1.0 1 0 0 1 1 1 1 RhoGAP domain DpnI_C PF17726.1 EGG03813.1 - 0.05 13.7 0.1 0.81 9.9 0.0 2.2 2 0 0 2 2 2 0 Dam-replacing HTH domain CBS PF00571.28 EGG03814.1 - 8e-32 109.5 4.9 1.3e-07 32.0 0.1 4.4 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 EGG03814.1 - 1.9e-05 24.5 0.3 4.7e-05 23.2 0.3 1.7 1 0 0 1 1 1 1 PB1 domain DUF4611 PF15387.6 EGG03814.1 - 0.6 10.4 7.0 2.6 8.3 7.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) ACPS PF01648.20 EGG03815.1 - 4.9e-11 42.8 0.0 9.5e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PRMT5_TIM PF17285.2 EGG03815.1 - 0.053 12.7 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 PRMT5 TIM barrel domain ECM11 PF15463.6 EGG03816.1 - 0.0071 16.9 0.1 0.018 15.6 0.1 1.7 1 0 0 1 1 1 1 Extracellular mutant protein 11 Syntaxin-6_N PF09177.11 EGG03818.1 - 0.051 14.1 2.6 0.052 14.1 0.6 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal RhoGEF PF00621.20 EGG03819.1 - 2e-29 103.2 9.7 3.5e-27 95.8 0.2 3.8 4 1 0 4 4 4 2 RhoGEF domain HAD_2 PF13419.6 EGG03820.1 - 4.8e-16 59.3 0.0 2.5e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG03820.1 - 2e-11 44.6 0.0 3.5e-11 43.8 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGG03820.1 - 3.9e-05 23.6 0.0 8.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EGG03820.1 - 0.12 12.8 0.0 0.42 11.0 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase RGS12_usC PF16612.5 EGG03820.1 - 0.22 12.0 3.3 0.46 10.9 3.3 1.5 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 eIF-3_zeta PF05091.12 EGG03823.1 - 7.1e-205 681.9 0.0 8.5e-205 681.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 EGG03823.1 - 0.13 11.7 0.0 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Cyclin PF08613.11 EGG03825.1 - 7.2e-20 72.0 0.6 7.2e-20 72.0 0.6 2.2 2 0 0 2 2 2 1 Cyclin Suf PF05843.14 EGG03826.1 - 1.2e-66 225.8 0.0 1.2e-66 225.8 0.0 3.5 4 2 1 5 5 5 1 Suppressor of forked protein (Suf) DUF4854 PF16146.5 EGG03826.1 - 0.014 15.7 0.2 0.033 14.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) TPR_6 PF13174.6 EGG03826.1 - 0.044 14.4 1.1 0.6 10.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG03826.1 - 0.094 13.6 6.0 0.85 10.6 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat CdvA PF18822.1 EGG03826.1 - 1.2 9.0 5.5 0.33 10.8 1.3 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain TPP_enzyme_M PF00205.22 EGG03829.1 - 2.3e-05 24.2 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain PUF PF00806.19 EGG03829.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat zf-LSD1 PF06943.12 EGG03829.1 - 0.12 12.2 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 LSD1 zinc finger Glutaredoxin PF00462.24 EGG03830.1 - 1.9e-12 47.2 0.1 4e-12 46.2 0.1 1.5 1 1 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EGG03830.1 - 0.001 19.4 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 EGG03830.1 - 0.013 15.6 0.0 0.09 12.8 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_2 PF13098.6 EGG03830.1 - 0.05 14.0 0.1 0.082 13.4 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Zn_ribbon_2 PF12674.7 EGG03830.1 - 0.12 13.0 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative zinc ribbon domain GST_N_2 PF13409.6 EGG03830.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Peroxidase_2 PF01328.17 EGG03833.1 - 2.1e-39 136.0 0.0 2.7e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 GWT1 PF06423.12 EGG03834.1 - 3.2e-26 92.3 2.0 1.4e-25 90.2 0.2 2.9 3 1 0 3 3 3 1 GWT1 G3P_antiterm PF04309.12 EGG03835.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator C1_2 PF03107.16 EGG03837.1 - 1.9 8.8 11.2 1.8 9.0 0.9 2.7 2 1 0 2 2 2 0 C1 domain Pkinase PF00069.25 EGG03838.1 - 1.4e-58 198.3 0.0 1.9e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG03838.1 - 8.4e-40 136.7 0.0 1.2e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG03838.1 - 8.3e-10 38.4 0.0 1.2e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGG03838.1 - 0.00043 19.2 0.0 0.00059 18.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGG03838.1 - 0.0014 17.7 0.0 0.0036 16.3 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGG03838.1 - 0.0043 16.2 0.0 0.0063 15.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EGG03838.1 - 0.015 15.3 0.1 0.035 14.0 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG03838.1 - 0.066 12.6 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MID_MedPIWI PF18296.1 EGG03839.1 - 0.01 15.6 1.2 0.014 15.2 1.2 1.3 1 0 0 1 1 1 0 MID domain of medPIWI SR-25 PF10500.9 EGG03839.1 - 0.22 11.1 12.2 0.37 10.4 12.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 EGG03839.1 - 0.29 9.6 3.7 0.34 9.4 3.7 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 EGG03840.1 - 1.2e-63 214.9 0.0 1.4e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG03840.1 - 6.1e-35 120.7 0.0 7.3e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG03840.1 - 6.2e-05 22.5 0.0 9.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGG03840.1 - 0.0012 17.8 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Neil1-DNA_bind PF09292.10 EGG03840.1 - 0.0063 16.5 0.1 0.016 15.2 0.0 1.7 2 0 0 2 2 2 1 Endonuclease VIII-like 1, DNA bind APH PF01636.23 EGG03840.1 - 0.0085 16.0 0.1 0.13 12.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG03840.1 - 0.026 13.5 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 EGG03840.1 - 0.04 13.4 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 EGG03840.1 - 0.091 12.4 0.0 2.4 7.7 0.0 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGG03840.1 - 0.13 11.6 0.1 0.28 10.5 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C2 PF00648.21 EGG03841.1 - 3.4e-22 78.8 0.0 5.6e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EGG03841.1 - 3e-09 37.3 0.0 2.2e-08 34.5 0.0 2.3 2 1 0 2 2 2 1 Calpain large subunit, domain III MIT PF04212.18 EGG03841.1 - 4e-08 33.2 0.0 6.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TruB_N PF01509.18 EGG03842.1 - 1.5e-35 122.7 0.0 1.9e-34 119.2 0.0 2.1 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EGG03842.1 - 5.4e-05 23.2 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PseudoU_synth_2 PF00849.22 EGG03842.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 RNA pseudouridylate synthase XdhC_CoxI PF02625.16 EGG03842.1 - 0.13 12.5 0.1 0.35 11.1 0.1 1.7 1 0 0 1 1 1 0 XdhC and CoxI family ABC_membrane PF00664.23 EGG03843.1 - 2e-57 194.9 19.5 5.5e-29 101.7 2.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGG03843.1 - 4.3e-48 163.3 0.0 4.9e-29 101.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGG03843.1 - 2.7e-09 37.3 1.3 6.2e-05 22.9 0.1 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG03843.1 - 3.1e-08 33.3 6.0 0.00057 19.4 0.0 4.9 4 1 1 5 5 5 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGG03843.1 - 5.3e-07 30.2 0.3 0.0039 17.6 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EGG03843.1 - 7.4e-07 28.8 0.9 0.035 13.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EGG03843.1 - 0.00052 19.8 0.0 2.2 7.9 0.0 3.0 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EGG03843.1 - 0.0014 18.9 0.7 1.9 8.8 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGG03843.1 - 0.0014 18.2 0.2 0.11 12.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGG03843.1 - 0.0039 17.7 0.4 1.1 9.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGG03843.1 - 0.005 17.4 0.2 0.69 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EGG03843.1 - 0.0063 16.6 0.3 2.7 8.0 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 EGG03843.1 - 0.011 15.7 0.1 3.3 7.6 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 EGG03843.1 - 0.016 14.9 0.2 0.5 10.1 0.0 2.8 3 1 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EGG03843.1 - 0.031 14.0 0.0 1.9 8.2 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_5 PF07728.14 EGG03843.1 - 0.034 14.1 0.1 4.2 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 EGG03843.1 - 0.044 13.2 2.4 11 5.4 0.1 3.9 4 0 0 4 4 4 0 PhoH-like protein APS_kinase PF01583.20 EGG03843.1 - 0.067 13.1 0.0 6 6.7 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 EGG03843.1 - 0.22 11.2 1.1 10 5.8 0.1 2.8 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EGG03843.1 - 0.41 10.8 3.6 7.6 6.7 0.2 2.6 2 0 0 2 2 2 0 AAA domain Asp PF00026.23 EGG03844.1 - 8.8e-25 87.8 0.0 1.5e-24 87.0 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG03844.1 - 1.3e-08 35.3 1.3 2.2e-05 24.8 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGG03844.1 - 0.025 14.4 0.1 0.055 13.2 0.1 1.7 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Lactonase PF10282.9 EGG03845.1 - 4.8e-59 200.3 0.0 6e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Spa1_C PF18218.1 EGG03845.1 - 0.15 12.5 0.1 0.7 10.3 0.0 2.0 2 0 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain Lactonase PF10282.9 EGG03846.1 - 3e-56 191.2 0.0 3.5e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HA2 PF04408.23 EGG03848.1 - 4.1e-25 88.1 1.8 4.7e-25 88.0 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGG03848.1 - 5.1e-19 68.4 0.0 1.4e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGG03848.1 - 2.9e-11 43.7 0.0 1.3e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG03848.1 - 8e-09 35.5 0.1 1.5e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 EGG03848.1 - 0.00014 21.5 0.3 0.00055 19.6 0.3 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 EGG03848.1 - 0.00056 20.2 0.1 0.0027 18.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGG03848.1 - 0.0019 18.6 0.0 0.0036 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EGG03848.1 - 0.0051 16.8 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 EGG03848.1 - 0.0056 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EGG03848.1 - 0.007 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EGG03848.1 - 0.043 13.8 0.0 5.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Dioxygenase_C PF00775.21 EGG03849.1 - 4.9e-46 156.5 0.0 6.9e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EGG03849.1 - 2.7e-28 97.6 0.0 6.1e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EGG03849.1 - 7.4e-05 22.9 0.0 0.00024 21.3 0.0 1.9 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EGG03849.1 - 0.039 14.0 0.1 15 5.7 0.1 3.1 2 1 0 2 2 2 0 CarboxypepD_reg-like domain SpaA PF17802.1 EGG03849.1 - 0.15 12.4 0.1 0.56 10.6 0.1 1.9 1 1 1 2 2 2 0 Prealbumin-like fold domain Prenyltrans PF00432.21 EGG03850.1 - 1.5e-25 88.6 13.2 1.8e-05 24.3 0.2 5.9 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EGG03850.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.5 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain SOG2 PF10428.9 EGG03852.1 - 0.56 9.3 13.7 0.61 9.2 13.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 EGG03852.1 - 3.2 6.3 7.3 3.1 6.3 7.3 1.0 1 0 0 1 1 1 0 Hamartin protein SPX PF03105.19 EGG03852.1 - 4.3 7.1 12.0 4.5 7.1 12.0 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 EGG03852.1 - 5.6 5.7 10.8 6 5.6 10.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HHH_8 PF14716.6 EGG03854.1 - 0.065 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF2681 PF10883.8 EGG03856.1 - 0.029 14.8 7.7 0.063 13.7 7.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Nop25 PF09805.9 EGG03856.1 - 0.5 10.8 17.3 0.031 14.8 11.4 1.8 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Barttin PF15462.6 EGG03856.1 - 5.9 6.6 11.8 0.22 11.3 4.5 2.0 1 1 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) SlyX PF04102.12 EGG03857.1 - 0.035 14.7 3.1 0.091 13.4 2.2 2.2 2 0 0 2 2 2 0 SlyX FlaC_arch PF05377.11 EGG03857.1 - 0.074 13.5 0.0 0.28 11.6 0.0 2.1 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF5427 PF10310.9 EGG03860.1 - 8.1e-49 166.8 22.6 2.6e-47 161.8 8.9 4.5 2 1 1 3 3 3 3 Family of unknown function (DUF5427) ATP-grasp_3 PF02655.14 EGG03863.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain SLD5_C PF16922.5 EGG03863.1 - 0.083 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus MMR_HSR1_Xtn PF16897.5 EGG03865.1 - 1.3e-09 38.1 0.2 2.5e-09 37.1 0.2 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EGG03865.1 - 8.5e-08 32.3 0.2 1.2e-07 31.7 0.2 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EGG03865.1 - 0.0019 18.5 0.1 0.0057 16.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain 6PF2K PF01591.18 EGG03865.1 - 0.0072 15.7 0.1 0.021 14.1 0.0 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase FeoB_N PF02421.18 EGG03865.1 - 0.019 14.5 0.8 0.036 13.6 0.8 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 EGG03865.1 - 0.032 14.5 0.2 0.052 13.8 0.2 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EGG03865.1 - 0.087 12.9 0.5 0.21 11.6 0.2 1.7 1 1 0 2 2 2 0 Dynamin family KTI12 PF08433.10 EGG03865.1 - 0.097 12.1 0.2 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Sas10_Utp3 PF04000.15 EGG03866.1 - 1.3e-11 45.0 0.4 2.9e-11 43.8 0.1 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Choline_kinase PF01633.20 EGG03867.1 - 3.9e-49 167.1 2.0 3.5e-47 160.7 2.0 2.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGG03867.1 - 2.5e-08 34.1 0.0 7.8e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGG03867.1 - 0.017 14.4 0.1 0.032 13.5 0.1 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase DUF2526 PF10735.9 EGG03869.1 - 0.15 12.2 0.3 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) NPR2 PF06218.11 EGG03870.1 - 1.6e-10 40.3 0.0 6.6e-09 35.0 0.0 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 KCH PF16944.5 EGG03871.1 - 1.1e-90 303.8 18.6 1.4e-90 303.4 18.6 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF3810 PF12725.7 EGG03871.1 - 0.45 9.8 5.2 3.1 7.1 5.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Nucleoporin_FG PF13634.6 EGG03874.1 - 8.6e-06 26.5 22.0 1.8e-05 25.5 22.0 1.6 1 1 0 1 1 1 1 Nucleoporin FG repeat region Transket_pyr PF02779.24 EGG03875.1 - 6.3e-46 156.3 0.0 1.9e-45 154.7 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGG03875.1 - 1.7e-37 128.1 0.2 3.9e-37 126.9 0.2 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aldedh PF00171.22 EGG03877.1 - 4.9e-160 533.0 0.0 5.5e-160 532.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ldh_2 PF02615.14 EGG03877.1 - 0.003 16.8 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase zf-H2C2_2 PF13465.6 EGG03878.1 - 0.0044 17.4 5.3 0.013 15.9 5.3 1.9 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGG03878.1 - 0.032 14.7 0.9 0.032 14.7 0.9 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG03878.1 - 0.19 12.7 7.7 0.3 12.0 0.9 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger Helicase_PWI PF18149.1 EGG03879.1 - 0.0037 17.4 0.5 0.0037 17.4 0.5 2.1 1 1 1 2 2 2 1 N-terminal helicase PWI domain Sec63 PF02889.16 EGG03880.1 - 3.3e-74 249.3 0.0 5.9e-74 248.5 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EGG03880.1 - 1.1e-33 116.5 0.5 1.3e-26 93.5 0.3 3.2 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 EGG03880.1 - 3e-12 46.9 0.1 1.4e-10 41.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGG03880.1 - 4.8e-07 30.1 2.4 5.1e-05 23.6 0.0 3.9 4 1 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGG03880.1 - 0.011 16.0 0.7 0.087 13.1 0.7 2.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGG03880.1 - 0.016 14.9 0.1 0.043 13.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGG03880.1 - 0.019 15.4 3.2 0.092 13.2 1.7 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGG03880.1 - 0.034 14.5 0.4 0.11 12.8 0.4 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGG03880.1 - 0.1 12.3 0.1 0.67 9.7 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein DehI PF10778.9 EGG03881.1 - 0.0067 16.6 0.5 0.53 10.4 0.0 2.8 3 0 0 3 3 3 1 Halocarboxylic acid dehydrogenase DehI GTP1_OBG PF01018.22 EGG03881.1 - 0.042 13.4 0.0 9.6 5.8 0.0 2.2 1 1 0 2 2 2 0 GTP1/OBG Acyl-CoA_dh_1 PF00441.24 EGG03883.1 - 6.8e-35 120.5 0.0 1.1e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EGG03883.1 - 2.6e-18 65.9 0.0 6e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EGG03883.1 - 3e-14 53.7 0.0 9.3e-14 52.1 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGG03883.1 - 3.2e-11 43.3 0.1 5.7e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGG03883.1 - 0.0031 17.8 0.0 0.0058 16.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain GN3L_Grn1 PF08701.11 EGG03885.1 - 2.3e-23 82.1 15.7 4.8e-23 81.1 15.7 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EGG03885.1 - 9.8e-17 61.1 0.7 2.5e-14 53.3 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG03885.1 - 1.3e-10 41.0 0.1 5.7e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGG03885.1 - 1.7e-05 24.8 0.1 0.12 12.2 0.1 2.8 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGG03885.1 - 0.0014 18.2 2.4 0.012 15.1 0.0 2.9 2 1 1 4 4 4 1 Elongation factor Tu GTP binding domain cobW PF02492.19 EGG03885.1 - 0.0043 16.7 0.1 0.11 12.1 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EGG03885.1 - 0.023 15.2 0.2 0.1 13.1 0.0 2.2 2 1 1 3 3 3 0 AAA domain Cwf_Cwc_15 PF04889.12 EGG03885.1 - 0.55 9.9 14.2 0.87 9.3 14.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Dynamin_N PF00350.23 EGG03885.1 - 2.2 8.3 9.7 1.7 8.7 0.1 3.5 2 2 1 3 3 3 0 Dynamin family Thioredoxin PF00085.20 EGG03887.1 - 2.3e-27 95.0 0.3 2.6e-27 94.8 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EGG03887.1 - 1.3e-07 31.5 0.1 1.5e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGG03887.1 - 1.5e-06 28.6 0.4 5.4e-06 26.8 0.4 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGG03887.1 - 5.2e-05 22.7 0.1 5.3e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EGG03887.1 - 5.9e-05 23.3 0.0 0.0016 18.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EGG03887.1 - 8.4e-05 22.5 0.1 9.4e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGG03887.1 - 0.00018 21.2 0.2 0.00019 21.1 0.2 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 EGG03887.1 - 0.00073 19.7 0.0 0.00089 19.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 EGG03887.1 - 0.012 15.4 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DIM1 PF02966.16 EGG03887.1 - 0.027 14.2 0.0 0.031 14.1 0.0 1.0 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin PF00085.20 EGG03888.1 - 2.4e-24 85.3 0.1 2.8e-24 85.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGG03888.1 - 2.6e-05 24.4 0.0 0.0025 18.1 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EGG03888.1 - 8.6e-05 22.5 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EGG03888.1 - 0.00015 21.3 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EGG03888.1 - 0.00051 19.8 0.1 0.01 15.5 0.1 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 EGG03888.1 - 0.0019 18.0 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGG03888.1 - 0.002 18.5 0.0 0.007 16.8 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain KaiB PF07689.12 EGG03888.1 - 0.16 11.7 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiB domain LIN37 PF15306.6 EGG03890.1 - 2 8.7 9.5 0.42 10.8 1.7 2.7 2 0 0 2 2 2 0 LIN37 TERB2 PF15101.6 EGG03891.1 - 0.73 9.9 3.4 1 9.4 3.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 AP1AR PF15745.5 EGG03891.1 - 1.8 8.1 8.6 3.3 7.3 8.6 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Beach PF02138.18 EGG03892.1 - 1.9e-108 362.0 0.0 3.1e-108 361.3 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EGG03892.1 - 1.7e-08 34.9 5.9 0.0069 17.2 0.0 5.6 4 0 0 4 4 4 2 WD domain, G-beta repeat PH_BEACH PF14844.6 EGG03892.1 - 7.2e-08 32.4 0.1 1.7e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 EGG03892.1 - 0.026 13.8 0.2 0.066 12.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) FYVE PF01363.21 EGG03892.1 - 0.066 13.4 15.0 0.032 14.4 11.4 2.3 2 0 0 2 2 2 0 FYVE zinc finger Siva PF05458.12 EGG03892.1 - 0.19 11.4 9.0 0.066 12.9 5.8 1.8 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Spt20 PF12090.8 EGG03894.1 - 0.0027 17.4 2.0 0.003 17.2 2.0 1.1 1 0 0 1 1 1 1 Spt20 family SKA1 PF07160.12 EGG03894.1 - 0.0098 15.8 3.7 0.013 15.4 3.7 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 PE PF00934.20 EGG03894.1 - 0.029 14.7 0.5 0.048 14.0 0.5 1.3 1 0 0 1 1 1 0 PE family Striatin PF08232.12 EGG03894.1 - 0.058 14.0 4.2 0.085 13.4 4.2 1.3 1 0 0 1 1 1 0 Striatin family RP-C_C PF11800.8 EGG03894.1 - 0.067 13.3 3.0 0.082 13.0 3.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region ASD2 PF08687.11 EGG03894.1 - 0.072 12.6 3.4 0.09 12.3 3.4 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Macoilin PF09726.9 EGG03894.1 - 0.31 9.5 6.9 0.37 9.3 6.9 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase_fungal PF17667.1 EGG03894.1 - 0.43 9.3 2.2 0.48 9.1 2.2 1.1 1 0 0 1 1 1 0 Fungal protein kinase Ndc1_Nup PF09531.10 EGG03894.1 - 0.59 8.7 7.6 0.62 8.7 7.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 EGG03894.1 - 0.63 8.7 3.5 0.77 8.4 3.5 1.2 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 EGG03894.1 - 0.67 8.7 7.0 0.76 8.5 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CCDC106 PF15794.5 EGG03894.1 - 0.74 9.5 9.2 0.92 9.2 9.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 GREB1 PF15782.5 EGG03894.1 - 2.4 5.2 8.3 2.6 5.0 8.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer UPRTase PF14681.6 EGG03895.1 - 1.2e-78 263.3 0.0 1.7e-78 262.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGG03895.1 - 3.4e-05 23.4 0.0 5.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 EGG03895.1 - 0.11 12.4 0.5 0.2 11.7 0.2 1.5 2 0 0 2 2 2 0 Influenza C non-structural protein (NS1) zf-primase PF09329.11 EGG03896.1 - 4.8e-10 39.1 0.3 1.3e-09 37.7 0.3 1.7 1 0 0 1 1 1 1 Primase zinc finger SDA1 PF05285.12 EGG03898.1 - 0.085 12.3 5.2 0.17 11.3 5.2 1.4 1 0 0 1 1 1 0 SDA1 Cu_amine_oxid PF01179.20 EGG03899.1 - 4.4e-149 496.9 0.0 5.4e-149 496.6 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EGG03899.1 - 6.5e-12 45.7 0.0 1.2e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain OMPdecase PF00215.24 EGG03900.1 - 9.5e-13 48.3 0.3 3.3e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family SUKH-4 PF14435.6 EGG03900.1 - 0.086 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 SUKH-4 immunity protein Retrotran_gag_2 PF14223.6 EGG03902.1 - 2.4e-05 24.0 0.0 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGG03902.1 - 0.13 12.1 0.2 0.75 9.7 0.1 2.1 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF1899 PF08953.11 EGG03903.1 - 3.9e-30 103.5 0.1 7.3e-30 102.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EGG03903.1 - 4.9e-20 71.2 1.2 1.1e-18 66.9 0.1 2.4 2 0 0 2 2 2 1 Type of WD40 repeat ANAPC4_WD40 PF12894.7 EGG03903.1 - 6.7e-07 29.5 0.1 0.015 15.5 0.0 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG03903.1 - 1.6e-06 28.7 3.7 1 10.3 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Sec2p PF06428.11 EGG03903.1 - 0.0082 16.1 5.5 0.015 15.3 5.5 1.4 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Nup160 PF11715.8 EGG03903.1 - 0.077 11.6 0.1 0.38 9.3 0.1 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF4391 PF14335.6 EGG03903.1 - 0.19 11.4 1.6 0.3 10.8 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Csm1_N PF18504.1 EGG03903.1 - 1.3 9.4 9.9 0.18 12.2 4.7 2.2 3 0 0 3 3 3 0 Csm1 N-terminal domain BUD22 PF09073.10 EGG03905.1 - 1.4 8.2 5.5 2 7.7 5.5 1.3 1 0 0 1 1 1 0 BUD22 Herpes_BLLF1 PF05109.13 EGG03905.1 - 2.1 6.2 38.0 2.8 5.8 38.0 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) BCDHK_Adom3 PF10436.9 EGG03907.1 - 1.8e-30 105.9 0.1 2.5e-30 105.5 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGG03907.1 - 8e-05 23.1 0.0 0.00027 21.4 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MIP PF00230.20 EGG03911.1 - 2e-09 37.5 1.7 2.6e-09 37.1 1.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein AA_permease_2 PF13520.6 EGG03913.1 - 1.4e-56 192.1 48.9 1.9e-56 191.7 48.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGG03913.1 - 8.3e-18 64.2 37.3 1.1e-17 63.8 37.3 1.1 1 0 0 1 1 1 1 Amino acid permease CarbpepA_inh PF02977.15 EGG03913.1 - 0.061 13.1 0.6 0.28 11.0 0.0 2.3 3 0 0 3 3 3 0 Carboxypeptidase A inhibitor NeA_P2 PF12312.8 EGG03914.1 - 0.79 9.1 5.9 0.083 12.3 1.2 1.7 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein PRIMA1 PF16101.5 EGG03914.1 - 2.7 8.1 7.1 1.2 9.2 3.1 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 UcrQ PF02939.16 EGG03915.1 - 6.6e-31 106.1 1.1 8.5e-31 105.7 1.1 1.1 1 0 0 1 1 1 1 UcrQ family Ferrochelatase PF00762.19 EGG03916.1 - 1.1e-107 359.9 0.0 1.2e-107 359.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase PEP_hydrolase PF09370.10 EGG03916.1 - 0.089 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like SDA1 PF05285.12 EGG03918.1 - 0.055 12.9 16.1 0.077 12.4 16.1 1.2 1 0 0 1 1 1 0 SDA1 PUB_1 PF18486.1 EGG03918.1 - 0.11 12.3 0.1 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain Nop14 PF04147.12 EGG03918.1 - 0.97 7.6 20.9 1.4 7.1 20.9 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4407 PF14362.6 EGG03918.1 - 1.9 7.7 4.6 4 6.7 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BUD22 PF09073.10 EGG03918.1 - 6.1 6.1 23.4 9.2 5.5 23.4 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EGG03918.1 - 6.2 5.0 13.8 9 4.5 13.8 1.2 1 0 0 1 1 1 0 CDC45-like protein ADH_N PF08240.12 EGG03922.1 - 0.065 13.1 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Ufd2P_core PF10408.9 EGG03924.1 - 2.4e-25 89.2 3.8 4.1e-23 81.9 3.8 2.0 1 1 0 1 1 1 1 Ubiquitin elongating factor core DUF3879 PF12995.7 EGG03925.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) ATP_sub_h PF10775.9 EGG03927.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 ATP synthase complex subunit h ORC5_C PF14630.6 EGG03929.1 - 1.5e-45 155.9 0.0 4e-45 154.5 0.0 1.6 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus PUB_1 PF18486.1 EGG03929.1 - 1.2 9.0 3.0 7.1 6.6 0.4 2.9 3 0 0 3 3 3 0 PNGase/UBA- or UBX-containing domain RA PF00788.23 EGG03930.1 - 1e-08 35.7 0.0 7e-08 33.0 0.0 2.5 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 EGG03930.1 - 5.9e-06 25.8 0.0 1.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGG03930.1 - 0.0046 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Calcipressin PF04847.12 EGG03931.1 - 1.1e-24 87.3 0.1 2.9e-19 69.5 0.4 2.7 2 1 0 2 2 2 2 Calcipressin ADH_N PF08240.12 EGG03932.1 - 9.7e-20 70.5 3.6 9.7e-20 70.5 3.6 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGG03932.1 - 6.4e-17 61.8 0.8 1.2e-16 60.9 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 EGG03932.1 - 0.005 16.4 0.2 0.0078 15.8 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EGG03932.1 - 0.017 14.5 0.1 0.035 13.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 EGG03932.1 - 0.082 13.0 1.0 0.16 12.1 1.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PQQ PF01011.21 EGG03932.1 - 0.091 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat CDP-OH_P_transf PF01066.21 EGG03933.1 - 1.8e-06 28.6 0.0 2.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Na_Ca_ex PF01699.24 EGG03937.1 - 1.2e-51 174.6 39.6 1.1e-28 100.1 14.2 2.7 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Egh16-like PF11327.8 EGG03938.1 - 0.00078 19.9 0.8 0.0013 19.2 0.8 1.3 1 0 0 1 1 1 1 Egh16-like virulence factor Vta1 PF04652.16 EGG03939.1 - 9.3e-47 158.6 0.3 1.2e-46 158.3 0.3 1.1 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 EGG03939.1 - 3.7e-13 48.9 0.4 3.7e-13 48.9 0.4 1.8 2 0 0 2 2 2 1 Vta1 C-terminal domain Cpn60_TCP1 PF00118.24 EGG03940.1 - 9.2e-158 525.9 2.3 1e-157 525.7 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_12 PF01670.16 EGG03941.1 - 4.1e-20 72.7 1.0 5e-20 72.4 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Peptidase_S29 PF02907.15 EGG03941.1 - 0.098 12.4 0.2 0.41 10.4 0.1 1.9 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease CCDC-167 PF15188.6 EGG03943.1 - 0.0052 17.1 0.2 0.01 16.1 0.2 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Ntox28 PF15605.6 EGG03943.1 - 0.0076 16.5 0.1 0.017 15.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial toxin 28 DUF3674 PF12426.8 EGG03945.1 - 0.012 15.6 1.3 0.023 14.7 1.3 1.4 1 0 0 1 1 1 0 RNA dependent RNA polymerase Glypican PF01153.19 EGG03945.1 - 3.9 6.2 6.8 6.7 5.4 6.8 1.3 1 0 0 1 1 1 0 Glypican PUFD PF16553.5 EGG03946.1 - 0.0043 17.2 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 BCORL-PCGF1-binding domain Chromo_2 PF18704.1 EGG03946.1 - 0.11 12.7 0.4 0.34 11.2 0.4 1.8 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 HEXIM PF15313.6 EGG03948.1 - 0.2 11.8 3.9 0.36 11.0 3.9 1.4 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein YopH_N PF09013.10 EGG03950.1 - 0.099 12.9 5.9 0.11 12.7 5.4 1.4 1 1 0 1 1 1 0 YopH, N-terminal Germane PF10646.9 EGG03950.1 - 1.3 9.8 4.0 1.8 9.4 3.9 1.4 1 1 0 1 1 1 0 Sporulation and spore germination TP53IP5 PF15331.6 EGG03950.1 - 4.3 7.4 12.5 5.3 7.1 12.5 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 MFS_1 PF07690.16 EGG03952.1 - 4.6e-43 147.5 41.7 6.5e-41 140.4 42.0 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG03952.1 - 1.5e-08 33.9 10.4 1.5e-08 33.9 10.4 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EGG03952.1 - 1e-06 27.5 23.1 7.2e-06 24.7 23.1 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2_3 PF16080.5 EGG03952.1 - 3.2 7.6 6.9 0.48 10.2 0.1 3.1 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Methyltrn_RNA_3 PF02598.17 EGG03954.1 - 0.072 12.6 0.1 0.086 12.3 0.1 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase GTP_EFTU PF00009.27 EGG03955.1 - 7.4e-36 123.5 0.0 2.1e-35 122.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGG03955.1 - 1.1e-19 70.5 0.0 3.3e-19 69.0 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EGG03955.1 - 8.5e-14 51.7 10.0 3.6e-10 40.1 0.2 4.0 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGG03955.1 - 2.3e-07 30.9 0.4 3.7e-06 27.0 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EGG03955.1 - 1.1e-05 25.3 0.4 4.8e-05 23.2 0.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 EGG03955.1 - 5.2e-05 23.4 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGG03955.1 - 0.0096 15.7 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 EGG03955.1 - 0.042 13.4 0.0 0.16 11.6 0.0 2.0 1 1 0 1 1 1 0 Ras family SurE PF01975.17 EGG03955.1 - 0.094 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Survival protein SurE TFIIA PF03153.13 EGG03955.1 - 1.2 9.0 28.6 2.5 8.0 28.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 EGG03955.1 - 2.2 6.4 44.2 4 5.5 44.2 1.3 1 0 0 1 1 1 0 Nop14-like family Hydrolase_4 PF12146.8 EGG03960.1 - 8e-17 61.3 0.0 1.1e-10 41.3 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG03960.1 - 4.9e-13 49.3 0.3 9.1e-10 38.6 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG03960.1 - 2.6e-06 28.2 0.0 3.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGG03960.1 - 0.00017 21.3 0.0 0.00035 20.3 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) AXE1 PF05448.12 EGG03960.1 - 0.0013 17.4 0.0 0.034 12.8 0.0 2.2 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EGG03960.1 - 0.0023 17.4 0.0 0.0077 15.7 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 EGG03960.1 - 0.0058 16.6 0.0 0.11 12.4 0.0 2.2 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 EGG03960.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EGG03960.1 - 0.12 12.4 0.1 0.21 11.7 0.1 1.4 1 1 0 1 1 1 0 Thioesterase domain SNF2_N PF00176.23 EGG03963.1 - 7.3e-36 123.6 0.5 8e-36 123.5 0.5 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGG03963.1 - 3.3e-06 27.0 0.0 3.9e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGG03963.1 - 4e-05 23.7 0.0 4.6e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGG03963.1 - 0.00069 19.3 0.0 0.00072 19.3 0.0 1.1 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Helicase_C PF00271.31 EGG03964.1 - 4.4e-15 56.0 0.0 7.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PPDK_N PF01326.19 EGG03964.1 - 0.091 12.0 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain ERGIC_N PF13850.6 EGG03966.1 - 0.032 14.6 0.7 0.043 14.1 0.7 1.1 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1137 PF06587.11 EGG03966.1 - 0.082 12.9 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1137) SR-25 PF10500.9 EGG03968.1 - 0.0024 17.5 15.1 0.0024 17.5 15.1 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 EGG03968.1 - 7 6.3 15.0 0.25 11.0 8.8 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 NuA4 PF09340.10 EGG03969.1 - 3.4e-22 78.1 0.4 6.2e-22 77.3 0.0 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF4407 PF14362.6 EGG03969.1 - 0.0088 15.4 1.6 0.01 15.2 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CotH PF08757.11 EGG03969.1 - 0.036 13.6 0.3 0.048 13.2 0.3 1.2 1 0 0 1 1 1 0 CotH kinase protein FAM76 PF16046.5 EGG03969.1 - 1.8 7.8 8.4 0.071 12.5 2.3 1.6 2 0 0 2 2 2 0 FAM76 protein Prefoldin_2 PF01920.20 EGG03969.1 - 7.5 6.6 13.0 0.73 9.8 3.8 2.3 2 0 0 2 2 2 0 Prefoldin subunit Asp PF00026.23 EGG03971.1 - 3.7e-70 236.8 5.6 5.2e-70 236.4 5.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG03971.1 - 2.3e-11 44.2 1.5 2.2e-10 41.1 1.5 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGG03971.1 - 0.00085 19.9 0.1 0.069 13.8 0.0 3.4 2 2 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EGG03971.1 - 0.034 14.7 0.2 1.5 9.4 0.0 3.2 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EGG03971.1 - 0.059 13.1 0.1 0.26 11.1 0.0 2.0 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal HLH PF00010.26 EGG03972.1 - 5.6e-12 45.4 0.1 1.1e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DNA_methylase PF00145.17 EGG03972.1 - 0.71 9.2 7.5 0.11 11.8 3.1 1.7 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase UCH_1 PF13423.6 EGG03974.1 - 1.1e-79 268.3 0.0 1.9e-79 267.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EGG03974.1 - 5.1e-22 79.2 0.0 9.4e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 EGG03974.1 - 9.7e-05 22.0 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase OrfB_Zn_ribbon PF07282.11 EGG03974.1 - 3.6 7.6 4.3 16 5.5 0.1 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain RMI1_N PF08585.12 EGG03975.1 - 0.076 12.8 0.5 0.11 12.2 0.5 1.3 1 0 0 1 1 1 0 RecQ mediated genome instability protein ACC_epsilon PF13822.6 EGG03975.1 - 0.22 12.2 1.5 1.9 9.2 1.5 2.6 1 1 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Phasin PF05597.11 EGG03980.1 - 1.4 9.0 5.6 0.23 11.5 0.7 1.9 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3854 PF12965.7 EGG03981.1 - 0.09 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) MFS_1 PF07690.16 EGG03985.1 - 1.2e-40 139.5 45.3 7.8e-39 133.6 43.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG03985.1 - 6.3e-11 41.8 5.0 6.3e-11 41.8 5.0 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EGG03985.1 - 6.5e-05 21.5 26.4 0.0051 15.3 26.0 2.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SNO PF01174.19 EGG03987.1 - 2.7e-44 151.3 0.0 3.6e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGG03987.1 - 2.8e-06 27.1 0.0 4.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Preseq_ALAS PF09029.10 EGG03990.1 - 0.11 12.9 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence Baculo_PEP_C PF04513.12 EGG03992.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_Mu_Gam PF07352.12 EGG03992.1 - 0.014 15.3 0.6 0.042 13.8 0.6 1.8 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein BRE1 PF08647.11 EGG03992.1 - 0.021 14.9 1.7 0.049 13.7 1.7 1.7 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase YscO PF07321.12 EGG03992.1 - 0.039 13.9 0.4 0.076 13.0 0.4 1.5 1 0 0 1 1 1 0 Type III secretion protein YscO FAM184 PF15665.5 EGG03992.1 - 0.071 12.9 1.3 0.13 12.1 1.3 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Dynactin_p22 PF07426.11 EGG03992.1 - 0.12 12.2 0.4 0.28 11.0 0.4 1.6 1 0 0 1 1 1 0 Dynactin subunit p22 Snapin_Pallidin PF14712.6 EGG03992.1 - 0.12 12.8 0.7 6.4 7.3 0.1 2.5 2 0 0 2 2 2 0 Snapin/Pallidin APP_E2 PF12925.7 EGG03992.1 - 0.13 12.0 2.1 0.24 11.1 2.1 1.4 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein PLU-1 PF08429.11 EGG03992.1 - 0.41 9.8 4.2 0.29 10.3 1.2 1.9 1 1 1 2 2 2 0 PLU-1-like protein DUF2383 PF09537.10 EGG03993.1 - 0.02 15.2 0.3 0.051 13.9 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Baculo_PEP_C PF04513.12 EGG03993.1 - 0.02 14.9 0.5 0.038 14.0 0.5 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 EGG03993.1 - 0.023 15.3 0.5 0.087 13.5 0.5 2.0 1 0 0 1 1 1 0 SlyX Filo_VP35 PF02097.15 EGG03993.1 - 0.07 12.2 0.6 0.17 10.9 0.6 1.6 1 0 0 1 1 1 0 Filoviridae VP35 DUF948 PF06103.11 EGG03993.1 - 0.099 12.9 0.4 0.21 11.9 0.4 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fusion_gly PF00523.18 EGG03993.1 - 0.21 9.8 0.6 0.32 9.2 0.6 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 DivIC PF04977.15 EGG03993.1 - 1.2 8.9 4.0 0.31 10.8 0.6 1.7 2 0 0 2 2 2 0 Septum formation initiator TFIIA PF03153.13 EGG03994.1 - 4.9 7.0 37.6 0.33 10.9 3.9 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit KH_6 PF15985.5 EGG03995.1 - 1.2e-08 35.1 0.0 2.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 KH domain Phage_BR0599 PF09356.10 EGG03996.1 - 0.019 15.3 3.2 29 5.1 0.1 4.0 3 0 0 3 3 3 0 Phage conserved hypothetical protein BR0599 DWNN PF08783.11 EGG03996.1 - 0.13 12.6 0.0 8.7 6.7 0.0 2.7 2 0 0 2 2 2 0 DWNN domain PuR_N PF09182.10 EGG03996.1 - 0.32 11.0 1.1 39 4.3 0.0 2.9 3 0 0 3 3 3 0 Bacterial purine repressor, N-terminal SR-25 PF10500.9 EGG03997.1 - 0.16 11.5 5.3 0.23 11.1 5.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NAD_binding_8 PF13450.6 EGG03999.1 - 8.1e-13 48.4 0.0 1.5e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGG03999.1 - 2.5e-08 33.6 0.0 2.6e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EGG03999.1 - 9.6e-05 22.1 0.2 0.00014 21.6 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG03999.1 - 0.0046 16.2 0.0 0.0053 16.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG03999.1 - 0.024 14.6 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 EGG03999.1 - 0.052 12.8 0.0 0.069 12.4 0.0 1.1 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EGG03999.1 - 0.091 11.8 0.2 0.12 11.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EGG03999.1 - 0.095 11.4 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EGG03999.1 - 0.19 11.0 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain WD40 PF00400.32 EGG04001.1 - 1.6e-22 79.3 0.8 5.9e-05 23.8 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG04001.1 - 4.4e-08 33.3 0.0 0.33 11.3 0.0 4.7 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Pap_E4 PF02711.14 EGG04003.1 - 0.045 14.7 1.8 0.045 14.7 1.8 3.3 3 0 0 3 3 3 0 E4 protein SUKH_5 PF14567.6 EGG04005.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall PBP_N PF17093.5 EGG04006.1 - 0.32 11.2 1.9 0.52 10.6 1.9 1.2 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus PdxJ PF03740.13 EGG04007.1 - 0.11 11.6 0.6 2.3 7.3 0.2 2.1 1 1 1 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ ODAPH PF15848.5 EGG04008.1 - 0.049 14.1 2.9 0.73 10.3 0.1 2.5 2 0 0 2 2 2 0 Odontogenesis associated phosphoprotein zf-CCHC_4 PF14392.6 EGG04009.1 - 0.031 14.0 1.2 0.055 13.2 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EGG04009.1 - 0.33 11.1 1.4 0.62 10.2 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Ufd2P_core PF10408.9 EGG04010.1 - 1e-11 44.2 0.2 2e-11 43.3 0.1 1.4 1 1 1 2 2 2 1 Ubiquitin elongating factor core Alpha_kinase PF02816.18 EGG04011.1 - 3.4e-19 69.7 0.2 3.4e-19 69.7 0.2 1.5 2 0 0 2 2 2 1 Alpha-kinase family Imm5 PF14423.6 EGG04011.1 - 0.09 13.0 0.1 0.16 12.2 0.1 1.4 1 1 0 1 1 1 0 Immunity protein Imm5 Helicase_C PF00271.31 EGG04012.1 - 4.8e-08 33.3 0.0 6.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain XRN_N PF03159.18 EGG04014.1 - 1.5e-87 293.0 0.0 1.8e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus GMP_synt_C PF00958.22 EGG04016.1 - 2.2e-42 143.0 0.1 6.2e-42 141.6 0.1 1.8 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EGG04016.1 - 5.1e-39 134.0 0.0 9.4e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EGG04016.1 - 2.3e-11 43.3 0.3 4.7e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EGG04016.1 - 7.1e-10 39.0 0.0 1.5e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 EGG04016.1 - 0.00031 19.7 0.1 0.00055 18.8 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 EGG04016.1 - 0.0032 17.1 0.0 0.0059 16.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 EGG04016.1 - 0.0085 15.4 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EGG04016.1 - 0.018 14.5 0.0 0.049 13.1 0.0 1.7 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 EGG04016.1 - 0.031 14.3 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 EGG04016.1 - 0.036 13.8 0.2 0.08 12.7 0.0 1.7 2 0 0 2 2 2 0 PP-loop family Asn_synthase PF00733.21 EGG04016.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase tRNA-synt_1 PF00133.22 EGG04021.1 - 7.1e-41 140.1 0.0 1.1e-28 99.9 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGG04021.1 - 1.8e-14 53.3 0.0 2e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGG04021.1 - 2.3e-13 50.4 0.0 5.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGG04021.1 - 6.4e-10 38.9 0.0 1.7e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DUF2911 PF11138.8 EGG04021.1 - 0.098 12.5 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) 3HCDH_N PF02737.18 EGG04022.1 - 3.6e-52 176.9 5.4 1e-51 175.4 5.4 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGG04022.1 - 7.7e-35 119.4 0.2 2.2e-34 117.9 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 EGG04022.1 - 1.3e-05 25.2 0.2 2.3e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 EGG04022.1 - 0.0083 16.3 2.7 0.028 14.6 2.7 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DXP_synthase_N PF13292.6 EGG04022.1 - 0.012 14.8 0.4 0.022 14.0 0.4 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase ELFV_dehydrog PF00208.21 EGG04022.1 - 0.02 14.6 0.5 0.036 13.8 0.5 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Methyltransf_12 PF08242.12 EGG04022.1 - 0.022 15.5 0.4 5.5 7.8 0.2 2.4 1 1 1 2 2 2 0 Methyltransferase domain ApbA PF02558.16 EGG04022.1 - 0.087 12.5 0.4 0.17 11.5 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HSDR_N_2 PF13588.6 EGG04022.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) F420_oxidored PF03807.17 EGG04022.1 - 0.17 12.5 3.7 0.63 10.7 3.5 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EGG04022.1 - 0.25 11.6 2.4 0.6 10.4 1.5 2.0 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TPR_19 PF14559.6 EGG04023.1 - 5.6e-21 74.8 8.3 0.00016 22.1 0.0 6.1 4 2 2 6 6 6 4 Tetratricopeptide repeat DnaJ PF00226.31 EGG04023.1 - 3.2e-19 68.8 1.2 1.1e-18 67.0 0.3 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 EGG04023.1 - 4.6e-18 63.8 1.9 0.048 13.8 0.0 7.6 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGG04023.1 - 1.3e-13 50.1 0.6 0.12 12.2 0.0 6.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGG04023.1 - 1.4e-11 44.2 5.9 0.12 13.2 0.1 6.4 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGG04023.1 - 4e-11 42.9 0.5 0.0039 17.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG04023.1 - 3.2e-09 37.3 4.5 0.34 11.6 0.0 4.8 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGG04023.1 - 1.8e-07 31.0 1.2 1.2 9.6 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG04023.1 - 1.8e-07 30.8 10.3 0.17 12.2 0.0 6.4 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGG04023.1 - 2e-06 28.0 2.0 0.081 13.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG04023.1 - 6.1e-06 26.4 12.9 0.098 12.9 0.4 5.4 3 2 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGG04023.1 - 1.5e-05 25.2 3.4 0.5 10.7 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG04023.1 - 0.00018 22.0 1.6 62 4.5 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGG04023.1 - 0.0003 20.4 3.0 1.5 8.6 0.1 5.0 4 1 1 5 5 5 2 TPR repeat TPR_7 PF13176.6 EGG04023.1 - 0.001 19.0 1.9 17 5.7 0.1 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EGG04023.1 - 0.0082 15.6 1.0 4.3 6.7 0.0 2.8 2 1 0 2 2 2 2 Coatomer epsilon subunit TPR_4 PF07721.14 EGG04023.1 - 0.02 15.5 0.0 8.8 7.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGG04023.1 - 1 9.8 4.2 25 5.3 0.1 3.5 2 1 0 3 3 3 0 Alkyl sulfatase dimerisation Acyl_transf_3 PF01757.22 EGG04024.1 - 3.6e-26 92.0 27.1 5e-26 91.6 27.1 1.2 1 0 0 1 1 1 1 Acyltransferase family DUF418 PF04235.12 EGG04024.1 - 4.6 7.1 15.4 0.78 9.7 10.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF418) Histidinol_dh PF00815.20 EGG04025.1 - 3.2e-159 530.3 0.0 4.2e-159 529.9 0.0 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EGG04025.1 - 4.1e-28 97.0 0.3 8.3e-28 96.0 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EGG04025.1 - 4e-12 46.4 0.0 1.8e-10 41.1 0.0 3.0 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 EGG04025.1 - 0.00014 22.0 0.8 0.00027 21.1 0.8 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Pex14_N PF04695.13 EGG04025.1 - 0.09 13.4 1.7 0.16 12.6 1.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MazG-like PF12643.7 EGG04025.1 - 0.09 13.0 0.2 0.31 11.3 0.2 1.9 1 0 0 1 1 1 0 MazG-like family SNF2_N PF00176.23 EGG04026.1 - 1.5e-20 73.2 0.2 2.9e-20 72.3 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 EGG04026.1 - 1.3e-09 38.5 6.3 4e-07 30.4 4.9 2.5 1 1 1 2 2 2 2 DNA-binding domain WD40_3 PF15911.5 EGG04027.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 WD domain, G-beta repeat PXA PF02194.15 EGG04029.1 - 1e-38 133.1 0.8 1e-38 133.1 0.8 1.7 2 0 0 2 2 2 1 PXA domain TCR_zetazeta PF11628.8 EGG04029.1 - 0.055 13.2 1.8 0.077 12.7 0.3 2.0 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain zf-ZPR1 PF03367.13 EGG04030.1 - 8.7e-08 32.2 0.0 1.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 ZPR1 zinc-finger domain AAA_assoc PF14363.6 EGG04030.1 - 0.13 12.6 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA DUF3295 PF11702.8 EGG04031.1 - 6.5e-13 48.9 13.9 6.5e-13 48.9 13.9 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3295) CAF1A PF12253.8 EGG04031.1 - 0.004 17.3 2.8 0.004 17.3 2.8 1.6 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A HTH_Tnp_4 PF13613.6 EGG04032.1 - 0.01 15.6 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Bac_DnaA_C PF08299.11 EGG04032.1 - 0.088 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix SPT2 PF08243.11 EGG04034.1 - 1.4e-09 38.5 9.2 1.7e-09 38.2 9.2 1.1 1 0 0 1 1 1 1 SPT2 chromatin protein Acyl-CoA_dh_1 PF00441.24 EGG04035.1 - 8.8e-47 159.1 0.7 2.1e-46 157.8 0.7 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGG04035.1 - 1e-27 97.0 0.0 2.4e-27 95.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGG04035.1 - 2.3e-24 85.4 0.0 4e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGG04035.1 - 4.5e-20 72.3 0.0 6.3e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4815 PF16075.5 EGG04035.1 - 0.11 10.8 0.0 0.16 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4815) HpaB_N PF11794.8 EGG04035.1 - 0.13 11.9 0.1 0.44 10.2 0.1 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Dishevelled PF02377.15 EGG04037.1 - 0.98 9.9 6.1 0.41 11.1 2.3 2.3 2 0 0 2 2 2 0 Dishevelled specific domain Herpes_BBRF1 PF04793.12 EGG04039.1 - 0.014 14.5 0.1 0.019 14.0 0.1 1.1 1 0 0 1 1 1 0 BRRF1-like protein Ni_hydr_CYTB PF01292.20 EGG04039.1 - 0.14 11.7 0.0 0.66 9.5 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 RecR PF02132.15 EGG04041.1 - 0.13 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 RecR protein DUF4734 PF15881.5 EGG04042.1 - 0.1 12.7 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4734) Coilin_N PF15862.5 EGG04043.1 - 2.3e-08 33.9 0.0 5.1e-05 23.1 0.0 3.3 2 1 0 2 2 2 2 Coilin N-terminus zf-RING_2 PF13639.6 EGG04044.1 - 1e-06 28.9 3.7 2.2e-06 27.9 3.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGG04044.1 - 0.00044 20.2 1.9 0.0019 18.1 1.9 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG04044.1 - 0.037 14.1 3.8 0.094 12.8 3.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG04044.1 - 0.055 13.4 2.1 0.16 11.9 2.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGG04044.1 - 0.062 13.1 2.4 0.13 12.1 2.4 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGG04044.1 - 0.07 13.0 3.7 0.17 11.8 3.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG04044.1 - 0.097 12.5 3.6 0.53 10.2 3.7 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EGG04044.1 - 0.18 11.7 1.9 0.44 10.5 1.9 1.7 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 EGG04044.1 - 0.2 11.5 3.4 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn-C2H2_12 PF18112.1 EGG04044.1 - 0.22 12.0 3.9 1.7 9.2 0.1 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_2 PF13639.6 EGG04046.1 - 0.0053 17.1 12.3 0.013 15.8 12.3 1.7 1 0 0 1 1 1 1 Ring finger domain Zn-C2H2_12 PF18112.1 EGG04046.1 - 0.5 10.9 0.1 0.5 10.9 0.1 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_2 PF13639.6 EGG04047.1 - 5.9e-07 29.7 3.7 9.7e-07 29.0 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGG04047.1 - 0.00037 20.4 2.5 0.0012 18.8 2.4 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG04047.1 - 0.018 15.1 3.6 0.036 14.1 3.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG04047.1 - 0.019 14.8 2.7 0.037 13.9 2.7 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGG04047.1 - 0.035 13.9 2.4 0.062 13.1 2.4 1.4 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 EGG04047.1 - 0.04 13.8 2.2 0.072 13.0 2.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-C2H2_12 PF18112.1 EGG04047.1 - 0.053 14.0 3.4 0.94 10.0 0.1 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_3 PF13920.6 EGG04047.1 - 0.071 13.0 3.9 0.27 11.1 3.9 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG04047.1 - 0.1 12.5 3.6 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 EGG04047.1 - 0.11 12.4 1.9 0.19 11.6 1.9 1.5 1 0 0 1 1 1 0 PHD-finger zinc_ribbon_9 PF14369.6 EGG04047.1 - 0.15 12.3 1.0 3.4 8.0 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon zf-ANAPC11 PF12861.7 EGG04047.1 - 0.26 11.4 1.8 2.3 8.3 2.0 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGG04047.1 - 0.32 10.8 2.5 0.81 9.5 2.5 1.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF2838 PF10998.8 EGG04048.1 - 1.1e-39 135.1 7.4 1.1e-39 135.1 7.4 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) UCH PF00443.29 EGG04050.1 - 9.7e-48 162.9 0.1 1.3e-47 162.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG04050.1 - 1e-14 54.9 11.0 1.2e-11 44.7 2.1 2.5 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Vanabin-2 PF11437.8 EGG04051.1 - 0.68 10.1 10.5 6.6 7.0 9.0 2.3 1 1 1 2 2 2 0 Vanadium-binding protein 2 RsbU_N PF08673.10 EGG04052.1 - 0.0062 16.6 0.2 0.021 14.9 0.2 1.9 1 0 0 1 1 1 1 Phosphoserine phosphatase RsbU, N-terminal domain Syntaxin_2 PF14523.6 EGG04052.1 - 1.9 8.9 5.9 26 5.2 0.9 3.2 2 1 1 3 3 3 0 Syntaxin-like protein HSCB_C PF07743.13 EGG04054.1 - 7.3e-09 36.0 8.5 3.7e-05 24.1 0.8 2.8 3 0 0 3 3 3 2 HSCB C-terminal oligomerisation domain Ogr_Delta PF04606.12 EGG04054.1 - 0.0049 16.8 3.0 0.0096 15.9 3.0 1.5 1 0 0 1 1 1 1 Ogr/Delta-like zinc finger RNHCP PF12647.7 EGG04054.1 - 0.019 14.9 0.2 0.038 13.9 0.2 1.4 1 0 0 1 1 1 0 RNHCP domain DnaJ PF00226.31 EGG04054.1 - 0.05 13.7 0.2 1.2 9.3 0.2 2.3 1 1 0 1 1 1 0 DnaJ domain HypA PF01155.19 EGG04054.1 - 0.11 12.6 0.4 0.33 11.0 0.1 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 EGG04054.1 - 0.15 11.5 2.0 0.17 11.3 0.5 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EGG04054.1 - 1.4 9.1 3.6 1.2 9.4 0.3 1.9 1 1 1 2 2 2 0 Zinc ribbon domain Aldedh PF00171.22 EGG04055.1 - 8e-72 242.2 0.0 1.2e-71 241.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ubiquitin_3 PF14836.6 EGG04055.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain COesterase PF00135.28 EGG04057.1 - 5.9e-66 223.4 0.0 8.3e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family PC-Esterase PF13839.6 EGG04058.1 - 0.00078 19.3 0.1 0.0048 16.7 0.1 2.0 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Zip PF02535.22 EGG04059.1 - 0.72 9.0 6.7 0.84 8.8 6.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGG04059.1 - 8 5.1 7.0 9.4 4.9 7.0 1.1 1 0 0 1 1 1 0 Presenilin Git3 PF11710.8 EGG04060.1 - 6.5e-10 39.1 12.3 5.6e-09 36.1 12.3 2.0 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EGG04060.1 - 9.8e-05 22.4 0.0 0.00035 20.6 0.0 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 EGG04060.1 - 0.00066 19.1 4.2 0.00082 18.8 4.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 EGG04060.1 - 0.42 9.7 10.3 1.5 7.9 10.2 1.8 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor DUF2534 PF10749.9 EGG04060.1 - 2 8.6 6.8 0.54 10.5 1.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2534) Alpha_kinase PF02816.18 EGG04061.1 - 3.6e-09 37.0 0.1 6.2e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Alpha-kinase family Stm1_N PF09598.10 EGG04061.1 - 7.4 7.5 7.3 18 6.2 6.8 2.0 1 1 0 1 1 1 0 Stm1 GH131_N PF18271.1 EGG04062.1 - 4.2e-49 167.6 0.0 4.7e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain zf-C2H2 PF00096.26 EGG04064.1 - 3.8e-07 30.2 5.8 0.001 19.4 1.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG04064.1 - 0.00087 19.6 3.4 0.4 11.2 0.6 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG04064.1 - 0.0011 19.6 7.7 0.0017 19.0 1.8 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGG04064.1 - 0.012 15.5 2.2 0.024 14.6 2.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger TRAF6_Z2 PF18048.1 EGG04064.1 - 0.014 15.5 0.1 0.028 14.5 0.1 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_jaz PF12171.8 EGG04064.1 - 0.047 14.0 2.7 0.058 13.7 0.8 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EGG04064.1 - 0.084 13.2 0.4 0.22 11.9 0.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 EGG04064.1 - 0.085 13.1 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 zinc-ribbon ABG_transport PF03806.13 EGG04065.1 - 0.14 10.3 0.0 0.16 10.2 0.0 1.0 1 0 0 1 1 1 0 AbgT putative transporter family CDT1_C PF16679.5 EGG04067.1 - 1.8e-08 34.7 0.1 1.8e-08 34.7 0.1 2.3 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain P22_AR_C PF10548.9 EGG04067.1 - 0.19 11.9 2.4 0.29 11.3 0.4 2.3 3 0 0 3 3 3 0 P22AR C-terminal domain Tyrosinase PF00264.20 EGG04068.1 - 7e-31 108.2 3.5 7.5e-31 108.1 0.8 2.2 2 1 0 2 2 2 1 Common central domain of tyrosinase KorB PF08535.10 EGG04069.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 KorB domain Ntox1 PF15500.6 EGG04070.1 - 0.26 11.7 1.6 0.29 11.5 1.0 1.5 1 1 1 2 2 2 0 Putative RNase-like toxin, toxin_1 INSIG PF07281.12 EGG04071.1 - 0.023 14.4 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) Intein_splicing PF14890.6 EGG04072.1 - 0.086 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Intein splicing domain LSM PF01423.22 EGG04073.1 - 3.1e-19 68.4 0.4 3.7e-19 68.2 0.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGG04073.1 - 4e-06 26.9 0.1 5.8e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EGG04073.1 - 0.019 15.1 0.1 0.023 14.8 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Proteasome PF00227.26 EGG04075.1 - 1.2e-59 201.0 0.0 1.9e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGG04075.1 - 2.5e-09 36.6 0.2 7.4e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature WD40 PF00400.32 EGG04076.1 - 1.2e-12 48.1 16.9 0.045 14.6 0.5 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG04076.1 - 0.00049 20.3 0.6 0.3 11.4 0.0 4.4 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG04076.1 - 0.0037 16.6 0.2 0.23 10.7 0.1 2.8 2 2 2 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 EGG04076.1 - 0.069 12.1 0.0 0.4 9.6 0.0 2.3 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_N PF14781.6 EGG04076.1 - 0.12 12.3 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal DUF1738 PF08401.11 EGG04076.1 - 0.29 11.2 2.1 8 6.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1738) CDC45 PF02724.14 EGG04076.1 - 4.5 5.5 11.5 9.3 4.4 11.5 1.6 1 0 0 1 1 1 0 CDC45-like protein Pec_lyase_C PF00544.19 EGG04077.1 - 6.4e-15 55.3 5.6 4.4e-14 52.6 5.6 2.0 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EGG04077.1 - 0.00021 21.2 6.4 0.00035 20.5 6.4 1.5 1 0 0 1 1 1 1 Right handed beta helix region AMMECR1 PF01871.17 EGG04078.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 AMMECR1 Actin PF00022.19 EGG04080.1 - 3.8e-41 141.0 0.0 2.2e-39 135.3 0.0 2.9 2 1 0 2 2 2 1 Actin MreB_Mbl PF06723.13 EGG04080.1 - 0.19 10.5 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein DASH_Dad4 PF08650.10 EGG04081.1 - 3.9e-24 84.4 7.1 4.1e-24 84.3 7.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 MCC-bdg_PDZ PF10506.9 EGG04081.1 - 0.021 14.9 1.0 0.16 12.0 1.0 2.1 1 1 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome FUSC-like PF12805.7 EGG04081.1 - 0.071 12.2 0.2 0.068 12.3 0.2 1.0 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Histone PF00125.24 EGG04082.1 - 1.2e-51 174.5 2.7 1.3e-51 174.4 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGG04082.1 - 0.0001 22.9 1.1 0.00012 22.6 1.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EGG04082.1 - 0.00015 22.1 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGG04082.1 - 0.00018 21.5 0.5 0.00028 20.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EGG04082.1 - 0.0038 17.5 0.1 0.0038 17.5 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGG04082.1 - 0.035 14.2 0.2 0.055 13.5 0.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PRAI PF00697.22 EGG04082.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase zf-Tim10_DDP PF02953.15 EGG04083.1 - 1.2e-19 69.6 4.9 1.2e-19 69.6 4.9 1.7 2 0 0 2 2 2 1 Tim10/DDP family zinc finger Insulin PF00049.18 EGG04083.1 - 0.28 12.2 0.3 0.28 12.2 0.3 2.2 1 1 1 2 2 2 0 Insulin/IGF/Relaxin family Ribosomal_L19 PF01245.20 EGG04084.1 - 5.8e-15 55.2 0.8 1.2e-14 54.2 0.8 1.5 1 1 0 1 1 1 1 Ribosomal protein L19 CCDC14 PF15254.6 EGG04086.1 - 0.17 10.5 1.5 0.17 10.5 1.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 CLLAC PF15675.5 EGG04087.1 - 0.093 12.3 1.1 0.17 11.5 1.1 1.4 1 0 0 1 1 1 0 CLLAC-motif containing domain NUC153 PF08159.12 EGG04088.1 - 2.4e-10 40.1 2.0 4.1e-10 39.3 2.0 1.4 1 0 0 1 1 1 1 NUC153 domain DASH_Duo1 PF08651.10 EGG04090.1 - 2.8e-18 65.5 0.5 2.8e-18 65.5 0.5 1.9 2 0 0 2 2 2 1 DASH complex subunit Duo1 adh_short_C2 PF13561.6 EGG04091.1 - 4.2e-57 193.4 0.0 5e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG04091.1 - 2.1e-49 167.6 0.0 2.7e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG04091.1 - 2.1e-09 37.5 0.0 2.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 KR domain DpaA_N PF16924.5 EGG04091.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain Cutinase PF01083.22 EGG04092.1 - 6.1e-27 94.7 1.5 7.3e-27 94.5 1.5 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EGG04092.1 - 0.00013 21.6 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 EGG04092.1 - 0.0022 17.9 0.0 0.003 17.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Thioesterase PF00975.20 EGG04092.1 - 0.078 13.1 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 EGG04092.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EGG04092.1 - 0.15 11.3 0.1 0.32 10.2 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Cutinase PF01083.22 EGG04093.1 - 3.7e-26 92.2 1.9 4.4e-26 91.9 1.9 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EGG04093.1 - 2.9e-05 23.8 0.1 3.5e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 EGG04093.1 - 0.0059 16.4 0.1 0.0093 15.8 0.1 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase VirJ PF06057.11 EGG04093.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.7 EGG04093.1 - 0.051 14.2 0.0 0.061 13.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.8 EGG04093.1 - 0.069 12.7 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Thioesterase PF00975.20 EGG04093.1 - 0.071 13.2 0.1 0.096 12.8 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.8 EGG04093.1 - 0.12 11.7 0.4 0.19 11.0 0.1 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S10 PF00450.22 EGG04094.1 - 3.1e-89 300.3 3.2 3.7e-89 300.0 3.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase 3HCDH_N PF02737.18 EGG04095.1 - 1.7e-07 31.3 0.2 2.5e-07 30.8 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-RVT PF13966.6 EGG04096.1 - 3.2e-05 24.6 0.8 0.00013 22.6 1.0 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase zinc_ribbon_5 PF13719.6 EGG04096.1 - 0.6 9.9 4.3 0.33 10.8 1.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_S10 PF00450.22 EGG04097.1 - 1.6e-89 301.2 0.1 2e-89 300.9 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RNase_P_p30 PF01876.16 EGG04098.1 - 2e-30 105.8 1.0 5e-30 104.6 0.0 2.2 2 1 0 2 2 2 1 RNase P subunit p30 YlbD_coat PF14071.6 EGG04098.1 - 0.0086 16.3 3.4 1.3 9.3 1.2 2.5 2 0 0 2 2 2 2 Putative coat protein DUF3106 PF11304.8 EGG04098.1 - 0.017 15.6 1.7 0.036 14.5 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Mt_ATP-synt_D PF05873.12 EGG04098.1 - 0.021 14.7 0.5 0.021 14.7 0.5 1.7 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF2254 PF10011.9 EGG04102.1 - 8 5.2 6.8 0.58 8.9 1.7 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Death_2 PF14786.6 EGG04103.1 - 0.042 13.8 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 Tube Death domain Podoplanin PF05808.11 EGG04103.1 - 3.2 7.8 9.5 3.3 7.8 4.8 2.1 1 1 0 2 2 2 0 Podoplanin DUF4763 PF15960.5 EGG04104.1 - 0.18 11.1 4.0 0.44 9.8 4.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Ribosomal_L29 PF00831.23 EGG04107.1 - 8.2e-18 64.1 2.1 8.2e-18 64.1 2.1 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein Endonuc_Holl PF10107.9 EGG04107.1 - 0.016 15.1 0.2 0.016 15.1 0.2 1.8 1 1 1 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase GATase_5 PF13507.6 EGG04108.1 - 1e-88 296.8 0.0 1.9e-88 295.9 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EGG04108.1 - 9.3e-39 133.1 0.0 4.6e-26 91.8 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EGG04108.1 - 1.4e-21 76.6 0.0 3e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EGG04108.1 - 1.6e-21 76.5 0.0 3.8e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 EGG04108.1 - 0.11 13.1 0.0 0.34 11.6 0.0 1.8 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain Campylo_MOMP PF05538.11 EGG04111.1 - 0.021 13.8 0.0 0.025 13.6 0.0 1.0 1 0 0 1 1 1 0 Campylobacter major outer membrane protein zf-C2H2_4 PF13894.6 EGG04115.1 - 2.6e-11 43.3 48.8 0.0026 18.5 2.3 7.3 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.26 EGG04115.1 - 4.5e-10 39.4 52.8 0.01 16.2 0.8 7.3 7 0 0 7 7 7 6 Zinc finger, C2H2 type Ogr_Delta PF04606.12 EGG04115.1 - 2.2e-06 27.5 30.2 0.0019 18.1 1.9 5.6 2 1 4 6 6 6 3 Ogr/Delta-like zinc finger zf-tcix PF14952.6 EGG04115.1 - 0.003 17.2 16.0 3.7 7.2 0.2 5.4 6 0 0 6 6 6 3 Putative treble-clef, zinc-finger, Zn-binding zf-DNA_Pol PF08996.10 EGG04115.1 - 0.0061 16.3 21.3 0.2 11.4 2.3 3.8 1 1 2 3 3 3 3 DNA Polymerase alpha zinc finger DUF5472 PF17566.2 EGG04115.1 - 0.38 10.7 9.8 4.4 7.3 0.9 4.1 1 1 3 4 4 4 0 Family of unknown function (DUF5472) Coat_F PF07875.12 EGG04115.1 - 0.45 10.8 1.8 8.6 6.7 0.0 3.2 3 1 0 3 3 3 0 Coat F domain OrsD PF12013.8 EGG04115.1 - 0.48 10.9 34.6 1.2 9.7 0.2 6.3 6 1 1 7 7 7 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_jaz PF12171.8 EGG04115.1 - 1 9.7 19.1 12 6.3 0.0 6.5 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EGG04115.1 - 1.5 8.9 16.4 0.42 10.7 0.6 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-CGNR PF11706.8 EGG04115.1 - 1.6 8.6 11.7 97 2.9 0.1 5.6 5 0 0 5 5 5 0 CGNR zinc finger FOXP-CC PF16159.5 EGG04115.1 - 1.7 9.3 25.4 3 8.5 0.2 6.4 2 2 5 7 7 7 0 FOXP coiled-coil domain DUF4668 PF15701.5 EGG04115.1 - 3.1 7.6 7.1 1.9 8.3 1.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4668) AMPK1_CBM PF16561.5 EGG04119.1 - 4.9e-07 29.9 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Lin-8 PF03353.15 EGG04119.1 - 8.1 5.9 14.3 0.14 11.7 1.9 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist PAPA-1 PF04795.12 EGG04120.1 - 0.33 11.8 1.0 0.76 10.6 1.0 1.5 1 0 0 1 1 1 0 PAPA-1-like conserved region CBM_5_12 PF02839.14 EGG04121.1 - 5.4 7.8 6.0 23 5.8 0.2 3.1 3 0 0 3 3 3 0 Carbohydrate binding domain Glyco_hydro_85 PF03644.13 EGG04123.1 - 2.5e-91 306.2 2.7 4.4e-91 305.4 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 ACP_PD PF04336.12 EGG04124.1 - 0.27 11.6 2.9 1.4 9.3 0.1 3.2 2 1 1 3 3 3 0 Acyl carrier protein phosphodiesterase Acetyltransf_2 PF00797.17 EGG04125.1 - 8.5e-32 110.9 0.0 3.9e-29 102.1 0.0 2.3 2 0 0 2 2 2 2 N-acetyltransferase DUF3314 PF11771.8 EGG04125.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3314) zf-TFIIIC PF12660.7 EGG04126.1 - 2.6e-11 43.4 4.4 1.9e-10 40.6 4.4 2.3 1 1 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Rho_GDI PF02115.17 EGG04132.1 - 9.9e-54 182.1 0.0 1.2e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Ribosomal_L12 PF00542.19 EGG04133.1 - 1.5e-23 82.9 9.7 1e-20 73.8 5.8 2.4 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EGG04133.1 - 3.2e-12 46.0 0.7 3.2e-12 46.0 0.7 2.9 3 0 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Rep_2 PF01719.17 EGG04133.1 - 0.063 13.1 0.7 4.6 7.0 0.1 2.1 2 0 0 2 2 2 0 Plasmid replication protein Phage_HK97_TLTM PF06120.11 EGG04133.1 - 0.077 12.2 3.1 0.18 10.9 1.3 1.9 2 0 0 2 2 2 0 Tail length tape measure protein Rx_N PF18052.1 EGG04133.1 - 0.083 13.2 0.1 0.23 11.8 0.1 1.8 1 1 0 1 1 1 0 Rx N-terminal domain CSTF2_hinge PF14327.6 EGG04133.1 - 0.24 11.9 4.8 1.1 9.7 0.9 2.6 2 1 1 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 DAHP_snth_FXD PF18152.1 EGG04133.1 - 0.31 10.9 0.1 0.31 10.9 0.1 2.3 3 0 0 3 3 3 0 DAHP synthase ferredoxin-like domain DUF3072 PF11272.8 EGG04133.1 - 0.32 10.9 4.0 2.7 8.0 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3072) DUF2120 PF09893.9 EGG04133.1 - 0.61 10.2 4.3 3.6 7.7 4.3 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) AMMECR1 PF01871.17 EGG04134.1 - 5.1e-42 143.3 0.0 6e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 DUF3636 PF12331.8 EGG04135.1 - 0.21 11.4 1.1 0.59 10.0 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3636) PQ-loop PF04193.14 EGG04136.1 - 3.1e-39 132.5 14.1 2.4e-19 68.9 0.9 2.8 2 0 0 2 2 2 2 PQ loop repeat PAP2_C PF14360.6 EGG04136.1 - 0.088 13.3 0.2 0.088 13.3 0.2 2.8 3 1 0 3 3 3 0 PAP2 superfamily C-terminal GPI-anchored PF10342.9 EGG04137.1 - 1.5e-10 41.7 0.5 2.6e-10 40.9 0.5 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 EGG04138.1 - 3.2e-06 27.8 4.7 3.2e-06 27.8 4.7 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1410 PF07198.11 EGG04138.1 - 0.011 16.2 1.1 0.026 15.0 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1410) RRM_1 PF00076.22 EGG04139.1 - 1.5e-38 130.5 2.2 1.8e-19 69.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG04139.1 - 0.00017 21.6 0.3 0.35 11.0 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 EGG04139.1 - 0.0028 17.5 0.4 0.46 10.4 0.0 2.6 2 1 0 2 2 2 1 Occluded RNA-recognition motif DbpA PF03880.15 EGG04139.1 - 0.0034 17.3 0.3 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 DbpA RNA binding domain DUF386 PF04074.12 EGG04139.1 - 0.0034 17.3 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 YhcH/YjgK/YiaL RRM_3 PF08777.11 EGG04139.1 - 0.0052 16.8 1.7 0.26 11.3 0.1 2.4 2 0 0 2 2 2 1 RNA binding motif PHM7_cyt PF14703.6 EGG04139.1 - 0.011 16.0 0.1 15 5.8 0.0 3.1 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 EGG04139.1 - 0.017 15.0 0.1 1.3 8.8 0.0 2.4 2 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 EGG04139.1 - 0.038 13.6 0.0 8.8 5.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 EGG04139.1 - 0.06 13.0 0.2 20 4.9 0.0 3.1 2 0 0 2 2 2 0 Ribonuclease B OB domain Med3 PF11593.8 EGG04140.1 - 0.0033 16.7 0.8 0.0039 16.5 0.8 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Tim54 PF11711.8 EGG04140.1 - 0.039 12.7 1.5 0.047 12.5 1.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TerB_C PF15615.6 EGG04140.1 - 0.06 13.6 2.4 0.12 12.7 2.4 1.5 1 1 0 1 1 1 0 TerB-C domain zf-C4H2 PF10146.9 EGG04140.1 - 0.1 12.9 1.0 0.13 12.5 1.0 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4164 PF13747.6 EGG04140.1 - 0.17 12.2 6.3 0.29 11.4 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) ZapB PF06005.12 EGG04140.1 - 3.3 8.2 8.4 0.16 12.4 2.4 1.8 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 EGG04140.1 - 3.6 7.4 7.7 0.32 10.8 3.1 1.7 2 0 0 2 2 2 0 Septum formation initiator DUF4336 PF14234.6 EGG04142.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) PI_PP_C PF18365.1 EGG04142.1 - 0.07 13.1 0.2 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain Tau95_N PF17682.1 EGG04142.1 - 0.098 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Tau95 Triple barrel domain CHMI PF02962.15 EGG04142.1 - 0.11 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 5-carboxymethyl-2-hydroxymuconate isomerase Peptidase_M49 PF03571.15 EGG04143.1 - 7.8e-221 734.2 0.0 9.2e-221 734.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 zf-C2H2_jaz PF12171.8 EGG04144.1 - 2.5e-08 34.0 2.0 0.0084 16.4 1.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EGG04144.1 - 1.3e-07 31.7 7.2 0.00088 19.6 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG04144.1 - 6.2e-07 29.7 6.9 0.0012 19.5 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGG04144.1 - 6.5e-06 26.0 7.8 0.014 15.4 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EGG04144.1 - 7.8e-06 26.1 3.0 0.01 16.2 0.6 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 EGG04144.1 - 5.8e-05 22.9 5.0 0.0067 16.3 0.0 3.2 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 EGG04144.1 - 0.00086 19.6 3.9 0.1 12.9 1.8 2.2 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 EGG04144.1 - 0.0031 17.9 0.5 0.065 13.7 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 EGG04144.1 - 0.0053 17.0 0.9 0.0067 16.7 0.9 1.2 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-DBF PF07535.12 EGG04144.1 - 0.0056 16.8 5.2 0.53 10.4 1.4 2.4 1 1 1 2 2 2 2 DBF zinc finger Prok-RING_1 PF14446.6 EGG04144.1 - 0.019 14.9 1.5 5 7.1 0.0 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-FCS PF06467.14 EGG04144.1 - 0.03 14.3 2.4 4.5 7.3 0.7 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Elf1 PF05129.13 EGG04144.1 - 0.035 14.2 2.9 0.39 10.8 0.7 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like PHD_4 PF16866.5 EGG04144.1 - 0.039 14.1 0.7 0.074 13.2 0.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 EGG04144.1 - 0.041 14.2 2.5 4 7.8 0.7 2.4 2 0 0 2 2 2 0 Ring finger domain zf_UBZ PF18439.1 EGG04144.1 - 0.061 12.9 1.8 0.71 9.5 0.3 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-RING_11 PF17123.5 EGG04144.1 - 0.067 12.9 2.4 1.4 8.8 0.6 2.4 2 0 0 2 2 2 0 RING-like zinc finger Zn-ribbon_8 PF09723.10 EGG04144.1 - 0.073 13.2 5.7 3.8 7.7 2.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain UBZ_FAAP20 PF15750.5 EGG04144.1 - 0.14 12.1 0.5 17 5.4 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Ta0938 PF11494.8 EGG04144.1 - 0.19 12.1 1.7 4 7.8 0.0 2.2 1 1 1 2 2 2 0 Ta0938 Sgf11 PF08209.11 EGG04144.1 - 0.27 10.8 3.3 17 5.1 0.1 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) FYVE PF01363.21 EGG04144.1 - 0.31 11.2 7.8 0.49 10.6 3.2 2.3 1 1 1 2 2 2 0 FYVE zinc finger Actin_micro PF17003.5 EGG04144.1 - 0.73 9.0 4.5 12 4.9 0.0 1.9 1 1 1 2 2 2 0 Putative actin-like family HNH PF01844.23 EGG04144.1 - 0.76 10.0 5.9 9.8 6.5 0.1 3.1 3 0 0 3 3 3 0 HNH endonuclease zf-AN1 PF01428.16 EGG04144.1 - 4.7 7.5 8.6 16 5.8 4.8 2.6 2 1 0 2 2 2 0 AN1-like Zinc finger FMN_dh PF01070.18 EGG04145.1 - 1.3e-101 340.1 0.0 9.6e-101 337.3 0.0 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EGG04145.1 - 1.1e-20 73.6 0.0 2.6e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 EGG04145.1 - 0.00016 20.8 0.1 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EGG04145.1 - 0.00081 18.6 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EGG04145.1 - 0.11 12.0 0.0 0.67 9.4 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein IF4E PF01652.18 EGG04146.1 - 3e-21 75.9 0.0 3.7e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PTS_IIA PF02255.16 EGG04147.1 - 0.88 9.7 4.0 4 7.6 0.2 2.6 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit CRAL_TRIO PF00650.20 EGG04149.1 - 1.2e-31 109.6 0.1 1.3e-30 106.2 0.2 2.3 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGG04149.1 - 1.3e-07 31.6 0.9 3.7e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGG04149.1 - 3.7e-05 23.9 0.2 7.1e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain tRNA-synt_1g PF09334.11 EGG04150.1 - 3.1e-85 286.3 0.4 3.8e-58 197.1 0.1 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGG04150.1 - 1.4e-10 40.1 1.3 2.3e-08 32.8 0.2 2.7 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGG04150.1 - 2.1e-05 24.5 0.0 4.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGG04150.1 - 2.9e-05 23.6 0.0 0.035 13.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Cnn_1N PF07989.11 EGG04153.1 - 0.0024 18.0 0.7 0.053 13.7 0.0 2.5 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 Acyltransferase PF01553.21 EGG04156.1 - 6.5e-28 97.0 0.0 8.8e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase ECF-ribofla_trS PF07155.12 EGG04156.1 - 0.037 14.0 0.5 0.047 13.7 0.5 1.2 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component DUF3789 PF12664.7 EGG04156.1 - 0.39 10.5 5.7 0.67 9.7 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) DUF4187 PF13821.6 EGG04158.1 - 2.4e-20 72.0 4.3 6.9e-20 70.6 4.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EGG04158.1 - 4e-07 29.8 0.2 0.00015 21.6 0.0 2.4 2 0 0 2 2 2 2 G-patch domain G-patch_2 PF12656.7 EGG04158.1 - 0.0031 17.6 0.5 0.045 13.8 0.5 2.6 1 1 0 1 1 1 1 G-patch domain SIN1 PF05422.12 EGG04158.1 - 0.64 10.6 8.6 3.7 8.1 1.8 2.9 2 1 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) SNF2_N PF00176.23 EGG04160.1 - 2.1e-51 174.7 0.1 4.1e-51 173.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG04160.1 - 9e-16 58.2 0.0 3.3e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EGG04160.1 - 9.5e-08 31.8 6.2 9.5e-08 31.8 6.2 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EGG04160.1 - 8.7e-07 29.1 0.0 1.9e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EGG04160.1 - 6.2e-06 26.0 9.0 6.2e-06 26.0 9.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG04160.1 - 6.3e-06 26.4 8.2 2.1e-05 24.7 8.2 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGG04160.1 - 1.6e-05 24.7 6.4 4.8e-05 23.2 6.4 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG04160.1 - 3e-05 23.9 6.7 3e-05 23.9 6.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGG04160.1 - 0.00012 22.2 3.8 0.00068 19.7 3.8 2.3 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EGG04160.1 - 0.0012 18.6 10.0 0.0056 16.5 10.0 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EGG04160.1 - 0.2 11.4 11.5 0.015 15.1 5.9 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 EGG04160.1 - 0.42 10.8 5.1 1.8 8.7 5.0 2.1 1 1 1 2 2 2 0 FYVE zinc finger zf-Nse PF11789.8 EGG04160.1 - 0.75 9.7 3.5 1.6 8.6 3.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit OrfB_Zn_ribbon PF07282.11 EGG04160.1 - 1.5 8.8 3.2 8.9 6.3 0.5 2.6 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-RING_11 PF17123.5 EGG04160.1 - 2.1 8.1 6.0 8.2 6.3 6.0 2.1 1 0 0 1 1 1 0 RING-like zinc finger DUF1272 PF06906.11 EGG04160.1 - 3.6 7.8 7.1 1.8 8.7 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 EGG04160.1 - 4.6 7.4 7.2 23 5.1 7.2 2.1 1 1 0 1 1 1 0 Double zinc ribbon TRAUB PF08164.12 EGG04162.1 - 1.2e-22 80.2 0.0 5.4e-22 78.1 0.0 2.2 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EGG04162.1 - 6.4e-22 78.7 3.2 1.2e-21 77.9 0.1 2.4 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor SART-1 PF03343.13 EGG04163.1 - 2.3e-156 522.0 75.3 2.3e-156 522.0 75.3 1.4 2 0 0 2 2 2 1 SART-1 family HA PF03457.14 EGG04163.1 - 8 6.9 12.7 0.86 10.0 0.8 4.1 3 1 0 3 3 3 0 Helicase associated domain F-box PF00646.33 EGG04164.1 - 0.013 15.4 1.1 0.8 9.7 0.3 3.5 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 EGG04164.1 - 0.019 14.9 2.6 0.046 13.6 0.9 2.6 2 1 0 2 2 2 0 F-box-like F-box-like_2 PF13013.6 EGG04164.1 - 0.054 13.5 1.2 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 F-box-like domain GCSF PF16647.5 EGG04168.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor TAFII28 PF04719.14 EGG04170.1 - 3.2e-31 107.2 0.0 6.3e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF3984 PF13136.6 EGG04170.1 - 0.021 14.2 6.9 0.032 13.6 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) TT_ORF2 PF02957.15 EGG04170.1 - 0.036 15.0 5.0 0.059 14.3 5.0 1.4 1 0 0 1 1 1 0 TT viral ORF2 Spt20 PF12090.8 EGG04170.1 - 0.07 12.7 11.5 0.095 12.3 11.5 1.2 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 EGG04170.1 - 0.45 9.1 3.1 0.59 8.8 3.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GET2 PF08690.10 EGG04170.1 - 0.45 10.1 11.0 0.51 10.0 11.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Tom22 PF04281.13 EGG04170.1 - 0.48 10.2 4.0 0.67 9.7 4.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF1980 PF09323.10 EGG04170.1 - 0.67 9.8 4.0 1 9.3 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Nucleo_P87 PF07267.11 EGG04170.1 - 0.84 8.4 10.2 1.1 8.0 10.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FYDLN_acid PF09538.10 EGG04170.1 - 2.6 8.8 15.4 5.1 7.8 15.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Presenilin PF01080.17 EGG04170.1 - 3.2 6.4 7.9 3.7 6.2 7.9 1.1 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 EGG04170.1 - 5.7 6.2 13.4 7.6 5.8 13.4 1.1 1 0 0 1 1 1 0 NOA36 protein PBP_sp32 PF07222.12 EGG04170.1 - 6.4 6.2 8.6 9.7 5.6 8.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Zn_clus PF00172.18 EGG04171.1 - 9.1e-07 28.9 6.8 1.9e-06 27.9 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAM-associated PF14303.6 EGG04171.1 - 0.18 12.5 0.2 0.18 12.5 0.2 2.7 1 1 0 2 2 2 0 No apical meristem-associated C-terminal domain CMV_US PF08001.11 EGG04174.1 - 0.057 12.7 0.1 0.09 12.0 0.1 1.2 1 0 0 1 1 1 0 CMV US FAM199X PF15814.5 EGG04175.1 - 5.6 5.9 5.7 3.7 6.5 4.4 1.4 1 1 0 1 1 1 0 Protein family FAM199X Thiolase_N PF00108.23 EGG04176.1 - 2e-87 292.8 1.5 2.6e-87 292.5 1.5 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGG04176.1 - 8.5e-42 141.7 3.1 1.8e-41 140.6 1.2 2.4 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGG04176.1 - 0.00078 19.1 0.6 0.00078 19.1 0.6 1.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DbpA PF03880.15 EGG04176.1 - 0.17 11.9 0.5 0.77 9.8 0.0 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain ACP_syn_III PF08545.10 EGG04176.1 - 3.5 7.6 6.2 16 5.4 0.1 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.25 EGG04177.1 - 2.8e-15 56.3 0.0 6.6e-15 55.1 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG04177.1 - 6.4e-10 39.0 0.0 1.2e-09 38.1 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG04177.1 - 6.2e-07 29.5 0.0 8.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Syntaxin_2 PF14523.6 EGG04178.1 - 2.4 8.6 6.0 1.5 9.2 1.2 2.7 4 0 0 4 4 4 0 Syntaxin-like protein GCM PF03615.15 EGG04179.1 - 0.066 13.1 3.0 0.24 11.3 3.0 1.9 1 1 0 1 1 1 0 GCM motif protein SDA1 PF05285.12 EGG04179.1 - 4.9 6.5 12.5 7.1 5.9 12.5 1.1 1 0 0 1 1 1 0 SDA1 Pribosyltran PF00156.27 EGG04180.1 - 1.3e-16 60.5 0.1 1.8e-16 60.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGG04180.1 - 0.0046 16.4 0.0 0.0078 15.7 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Complex1_LYR PF05347.15 EGG04181.1 - 1.9e-08 34.2 3.0 2e-08 34.1 0.9 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) CENP-T_C PF15511.6 EGG04183.1 - 3.7e-08 33.4 0.0 4.6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EGG04183.1 - 6.8e-05 23.0 0.1 8.9e-05 22.6 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGG04183.1 - 0.00013 22.2 0.0 0.00017 21.9 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EGG04183.1 - 0.00093 19.6 0.1 0.0012 19.2 0.1 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGG04183.1 - 0.0013 19.0 0.1 0.0022 18.2 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGG04183.1 - 0.056 13.5 0.0 0.061 13.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit UPF0137 PF03677.13 EGG04183.1 - 0.095 12.5 0.1 0.1 12.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Auto_anti-p27 PF06677.12 EGG04184.1 - 9.1e-27 92.9 6.3 1.1e-13 51.1 2.0 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CLIP1_ZNF PF16641.5 EGG04184.1 - 0.31 11.0 0.3 0.31 11.0 0.3 2.1 2 0 0 2 2 2 0 CLIP1 zinc knuckle GTP_EFTU PF00009.27 EGG04185.1 - 1.5e-44 151.9 0.0 2.8e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGG04185.1 - 3.9e-33 114.1 0.0 1.8e-32 112.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGG04185.1 - 3.8e-10 40.0 0.4 1.2e-09 38.4 0.4 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGG04185.1 - 0.00088 19.3 0.1 0.0036 17.4 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Rpn9_C PF18261.1 EGG04185.1 - 0.21 11.2 0.6 0.47 10.1 0.6 1.5 1 0 0 1 1 1 0 Rpn9 C-terminal helix Gpi16 PF04113.14 EGG04186.1 - 0.11 10.9 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component SPC12 PF06645.13 EGG04187.1 - 5.2e-31 106.5 0.9 6.3e-31 106.3 0.9 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF702 PF05142.12 EGG04188.1 - 0.37 11.3 5.1 0.65 10.5 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Glyco_hydro_47 PF01532.20 EGG04189.1 - 3.6e-110 369.0 0.0 5.5e-110 368.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CHCH PF06747.13 EGG04190.1 - 4.4e-06 26.7 5.7 5.7e-06 26.3 5.7 1.2 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 EGG04190.1 - 0.0096 15.6 1.0 0.012 15.3 1.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EGG04190.1 - 0.031 14.3 0.7 0.043 13.8 0.7 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EGG04190.1 - 0.058 13.4 3.9 0.083 12.9 3.9 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CxC1 PF18802.1 EGG04192.1 - 8.8e-23 80.4 0.3 3.9e-19 68.7 0.0 2.3 1 1 1 2 2 2 2 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGG04192.1 - 1.5e-08 34.5 0.1 3.4e-08 33.4 0.0 1.6 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EGG04192.1 - 3.6e-08 33.5 0.1 7.2e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG04192.1 - 0.0094 15.8 0.1 0.02 14.7 0.1 1.6 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases Hairy_orange PF07527.13 EGG04192.1 - 0.092 13.0 0.0 0.82 9.9 0.2 2.4 2 0 0 2 2 2 0 Hairy Orange SEA PF01390.20 EGG04193.1 - 0.033 14.3 1.0 0.93 9.6 0.0 3.1 3 1 0 3 3 3 0 SEA domain Forkhead PF00250.18 EGG04195.1 - 7.8e-24 83.8 0.0 8.7e-24 83.6 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain SCIMP PF15050.6 EGG04197.1 - 0.041 14.3 0.5 0.11 13.0 0.5 1.7 1 0 0 1 1 1 0 SCIMP protein PA28_beta PF02252.18 EGG04198.1 - 4.2e-40 136.7 0.0 2.8e-39 134.1 0.0 1.9 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit Zn_Tnp_IS1 PF03811.13 EGG04199.1 - 0.069 12.9 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 InsA N-terminal domain Alpha_kinase PF02816.18 EGG04200.1 - 1.6e-20 74.0 0.0 2.1e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family MIP PF00230.20 EGG04204.1 - 6.9e-21 75.0 2.7 8.8e-20 71.4 2.7 2.0 1 1 0 1 1 1 1 Major intrinsic protein PIG-U PF06728.13 EGG04204.1 - 0.044 12.8 0.3 0.057 12.5 0.3 1.1 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U Peptidase_M16_M PF16187.5 EGG04205.1 - 1.8e-22 79.9 0.0 2.3e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Aldedh PF00171.22 EGG04206.1 - 1.2e-71 241.6 0.0 1.5e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNA_pol_Rpb5_C PF01191.19 EGG04206.1 - 0.2 11.5 2.1 3.1 7.7 0.0 3.0 2 1 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain DUF4407 PF14362.6 EGG04207.1 - 3.9 6.8 8.1 7.2 5.9 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Myb_DNA-bind_6 PF13921.6 EGG04208.1 - 3e-28 97.9 10.9 1.5e-10 41.2 2.5 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGG04208.1 - 9.9e-28 96.1 12.2 1.2e-11 44.5 0.2 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 EGG04208.1 - 0.011 16.0 8.9 1.4 9.2 0.7 3.4 2 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TrkH PF02386.16 EGG04213.1 - 1.2e-109 367.1 15.1 2.1e-106 356.4 7.7 2.1 2 0 0 2 2 2 2 Cation transport protein E1-E2_ATPase PF00122.20 EGG04214.1 - 8.7e-38 129.6 0.8 8.7e-38 129.6 0.8 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGG04214.1 - 1e-36 126.4 4.3 1e-36 126.4 4.3 3.2 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGG04214.1 - 1.5e-18 67.9 1.5 8.2e-15 55.7 1.5 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG04214.1 - 5.4e-15 55.3 0.0 1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGG04214.1 - 1.2e-07 31.2 0.2 4.1e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG04214.1 - 3.1e-05 23.9 0.3 5.9e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 EGG04214.1 - 0.028 14.2 3.5 2.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) E1-E2_ATPase PF00122.20 EGG04215.1 - 1.1e-36 126.0 2.3 1.9e-36 125.2 0.5 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGG04215.1 - 1.7e-35 122.4 3.7 1.7e-35 122.4 3.7 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGG04215.1 - 1.9e-17 64.3 0.6 1.2e-14 55.1 0.6 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG04215.1 - 8e-13 48.3 0.0 1.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGG04215.1 - 2.9e-07 30.1 0.0 9e-07 28.5 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG04215.1 - 3.3e-05 23.8 0.3 5.6e-05 23.0 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase COX6C PF02937.15 EGG04215.1 - 0.2 11.8 0.0 0.58 10.3 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc PRA1 PF03208.19 EGG04215.1 - 0.91 9.1 4.3 5.8 6.5 0.8 2.8 2 0 0 2 2 2 0 PRA1 family protein PaO PF08417.12 EGG04216.1 - 0.042 14.0 0.1 0.071 13.3 0.1 1.3 1 0 0 1 1 1 0 Pheophorbide a oxygenase Smg4_UPF3 PF03467.15 EGG04220.1 - 9.7e-50 169.0 0.1 2.2e-49 167.8 0.1 1.6 1 0 0 1 1 1 1 Smg-4/UPF3 family COX7a PF02238.15 EGG04221.1 - 3.7e-21 75.3 0.6 4.3e-21 75.1 0.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII PsbL PF02419.17 EGG04221.1 - 0.04 13.9 0.3 0.073 13.1 0.3 1.4 1 0 0 1 1 1 0 PsbL protein Sec7 PF01369.20 EGG04223.1 - 2.3e-28 99.1 0.2 2.6e-28 99.0 0.2 1.0 1 0 0 1 1 1 1 Sec7 domain Acyltransferase PF01553.21 EGG04225.1 - 5.5e-16 58.4 0.0 7.5e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EGG04225.1 - 6.4e-10 39.0 0.0 1.8e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus SIR2 PF02146.17 EGG04226.1 - 5.7e-31 107.8 0.0 4.9e-19 68.9 0.0 2.6 3 0 0 3 3 3 2 Sir2 family DUF5101 PF17031.5 EGG04226.1 - 0.028 14.5 1.7 0.063 13.4 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) FtsH_ext PF06480.15 EGG04226.1 - 7 7.1 6.6 0.81 10.1 0.2 2.6 2 2 0 2 2 2 0 FtsH Extracellular Syntaxin_2 PF14523.6 EGG04229.1 - 0.11 12.8 0.4 1.4 9.3 0.2 2.1 2 0 0 2 2 2 0 Syntaxin-like protein DUF4264 PF14084.6 EGG04229.1 - 0.14 11.8 0.2 5.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) NAD_binding_8 PF13450.6 EGG04230.1 - 5.2e-12 45.8 0.0 9.2e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGG04230.1 - 1.1e-07 31.5 0.0 1.1e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EGG04230.1 - 0.00037 20.2 0.1 0.00054 19.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG04230.1 - 0.0089 15.3 0.0 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG04230.1 - 0.026 14.5 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EGG04230.1 - 0.093 11.4 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EGG04230.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EGG04230.1 - 0.2 10.9 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CHASE3 PF05227.13 EGG04231.1 - 0.15 12.0 0.2 0.29 11.0 0.2 1.4 1 0 0 1 1 1 0 CHASE3 domain ETRAMP PF09716.10 EGG04231.1 - 1.1 9.4 6.4 47 4.2 6.4 3.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Gtr1_RagA PF04670.12 EGG04232.1 - 3.5e-51 173.8 0.3 4.2e-51 173.6 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EGG04232.1 - 2.1e-06 27.3 0.0 3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG04232.1 - 0.00024 21.1 0.0 0.00042 20.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DBD_HTH PF18430.1 EGG04232.1 - 0.0071 16.1 0.2 0.057 13.2 0.1 2.3 2 0 0 2 2 2 1 Putative DNA-binding domain Roc PF08477.13 EGG04232.1 - 0.0072 16.5 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GSAP-16 PF14959.6 EGG04232.1 - 0.038 13.9 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 gamma-Secretase-activating protein C-term LptE PF04390.12 EGG04232.1 - 0.14 12.8 0.5 0.28 11.9 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide-assembly AAA_16 PF13191.6 EGG04232.1 - 0.17 12.2 0.0 0.86 10.0 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain HMGL-like PF00682.19 EGG04233.1 - 2e-13 50.5 0.1 8.8e-07 28.7 0.0 2.2 1 1 1 2 2 2 2 HMGL-like DUF2491 PF10679.9 EGG04235.1 - 0.041 13.1 0.1 0.068 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) RHD3 PF05879.12 EGG04237.1 - 2.2e-234 780.0 9.5 3.8e-234 779.2 9.5 1.3 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EGG04237.1 - 1.9e-06 27.3 0.1 1.9e-06 27.3 0.1 1.9 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EGG04237.1 - 6.7e-06 26.2 0.0 2.5e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGG04237.1 - 2e-05 24.7 0.6 6.8e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.6 EGG04237.1 - 0.022 15.0 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain T4_Rnl2_C PF18043.1 EGG04237.1 - 8.5 6.6 7.8 1.1 9.4 0.2 3.1 3 0 0 3 3 3 0 T4 RNA ligase 2 C-terminal Melibiase_2 PF16499.5 EGG04239.1 - 2.2e-21 76.3 0.3 5.7e-13 48.7 0.1 2.2 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 EGG04239.1 - 2.3e-07 30.8 0.2 6.8e-07 29.3 0.2 1.8 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Glyco_hydro_30C PF17189.4 EGG04239.1 - 0.01 16.0 0.0 8.4 6.7 0.0 2.7 2 1 1 3 3 3 0 Glycosyl hydrolase family 30 beta sandwich domain Cellulase PF00150.18 EGG04240.1 - 1.7e-17 63.8 0.0 1.9e-10 40.6 0.0 3.2 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EGG04240.1 - 1.5e-15 57.5 0.1 3.1e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_14 PF01373.17 EGG04240.1 - 0.053 12.5 0.1 0.19 10.6 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 14 Baculo_PEP_C PF04513.12 EGG04241.1 - 0.066 13.2 3.0 0.33 11.0 0.2 3.4 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FRG2 PF15315.6 EGG04242.1 - 0.019 15.2 6.0 0.021 15.0 6.0 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Umbravirus_LDM PF04817.12 EGG04242.1 - 0.071 12.5 6.5 0.088 12.1 6.5 1.1 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family Podoplanin PF05808.11 EGG04242.1 - 2.1 8.4 8.6 2.3 8.3 8.6 1.1 1 0 0 1 1 1 0 Podoplanin MFS_1 PF07690.16 EGG04244.1 - 1.2e-32 113.2 24.2 2.8e-32 112.0 22.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.12 EGG04244.1 - 0.024 14.8 0.7 0.12 12.5 0.2 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Atthog PF18800.1 EGG04246.1 - 0.01 15.7 1.5 0.023 14.6 1.4 1.7 1 1 0 1 1 1 0 Attenuator of Hedgehog Pox_A14 PF05767.12 EGG04246.1 - 0.069 13.3 3.4 0.38 11.0 2.0 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 MARVEL PF01284.23 EGG04246.1 - 0.11 12.5 9.8 0.27 11.3 9.8 1.7 1 1 0 1 1 1 0 Membrane-associating domain Amastin PF07344.11 EGG04246.1 - 0.17 11.7 11.2 0.042 13.7 7.5 1.8 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF423 PF04241.15 EGG04246.1 - 9.9 6.4 8.6 4.8 7.5 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF423) DnaJ PF00226.31 EGG04247.1 - 5.5e-10 39.2 0.2 2.6e-09 37.1 0.0 2.2 3 0 0 3 3 3 1 DnaJ domain TPR_19 PF14559.6 EGG04247.1 - 0.07 13.7 0.3 2.8 8.5 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat Dscam_C PF12355.8 EGG04250.1 - 0.078 13.9 5.6 0.11 13.5 5.6 1.4 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal JmjC PF02373.22 EGG04251.1 - 2e-13 50.8 0.1 8.2e-13 48.8 0.1 2.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGG04251.1 - 3.3e-06 27.0 0.1 3.3e-06 27.0 0.1 2.9 2 1 0 2 2 2 1 Cupin-like domain ARF7EP_C PF14949.6 EGG04251.1 - 5.7 7.6 14.0 3.4 8.3 0.3 4.3 3 1 0 3 3 3 0 ARF7 effector protein C-terminus Peptidase_S8 PF00082.22 EGG04252.1 - 3.6e-41 141.4 0.4 3.6e-41 141.4 0.4 1.7 2 0 0 2 2 2 1 Subtilase family Methyltransf_28 PF02636.17 EGG04253.1 - 3e-35 122.1 0.0 4.2e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 EGG04253.1 - 0.061 14.1 0.0 0.12 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LigD_N PF13298.6 EGG04254.1 - 0.064 13.5 0.1 3.6 7.9 0.0 2.6 2 0 0 2 2 2 0 DNA polymerase Ligase (LigD) Melittin PF01372.17 EGG04255.1 - 0.44 10.6 2.8 2.4 8.3 0.0 3.5 3 0 0 3 3 3 0 Melittin RNA_pol_Rpb4 PF03874.16 EGG04256.1 - 6.3e-16 58.8 1.3 2.6e-15 56.8 1.3 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb4 DrrA_P4M PF14860.6 EGG04256.1 - 0.059 13.2 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Acetyltransf_10 PF13673.7 EGG04257.1 - 6.5e-14 52.0 0.0 1.5e-13 50.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG04257.1 - 6.4e-10 39.3 0.0 1.2e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG04257.1 - 9.3e-10 38.8 0.0 1.5e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGG04257.1 - 9.2e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGG04257.1 - 0.0023 18.0 0.0 0.0039 17.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Amidohydro_1 PF01979.20 EGG04258.1 - 1.5e-11 44.2 0.0 1.6e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Neur_chan_memb PF02932.16 EGG04262.1 - 0.012 15.6 1.5 0.015 15.4 1.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 EGG04262.1 - 0.15 10.3 7.9 0.18 10.0 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.6 EGG04262.1 - 0.16 11.9 8.9 0.22 11.5 8.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4551 PF15087.6 EGG04262.1 - 4.5 6.0 9.4 5.4 5.7 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Glyco_hydro_2_N PF02837.18 EGG04264.1 - 2.1e-12 47.3 0.0 8.9e-12 45.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EGG04264.1 - 1.3e-09 38.7 0.0 3.6e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 EGG04264.1 - 0.0013 17.9 0.1 0.0091 15.1 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain DRIM PF07539.12 EGG04265.1 - 4.4e-161 537.3 0.5 4.4e-161 537.3 0.5 5.0 4 2 1 5 5 5 2 Down-regulated in metastasis HEAT PF02985.22 EGG04265.1 - 0.00013 21.9 0.4 34 5.1 0.0 7.3 7 0 0 7 7 7 0 HEAT repeat MOR2-PAG1_C PF14225.6 EGG04265.1 - 0.032 14.1 8.7 0.28 11.0 0.9 4.9 4 1 0 4 4 4 0 Cell morphogenesis C-terminal FerA PF08165.11 EGG04265.1 - 0.063 13.2 0.5 11 6.1 0.0 3.3 2 0 0 2 2 2 0 FerA (NUC095) domain MMS19_N PF14500.6 EGG04265.1 - 0.14 11.7 18.1 0.048 13.2 3.1 6.1 7 1 0 7 7 7 0 Dos2-interacting transcription regulator of RNA-Pol-II Arm PF00514.23 EGG04265.1 - 0.22 11.6 2.1 7.2 6.8 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TetR_C_31 PF17940.1 EGG04265.1 - 0.86 9.8 5.3 6.1 7.1 0.2 3.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain FOXP-CC PF16159.5 EGG04266.1 - 1.2 9.8 4.2 2.1 9.0 4.2 1.4 1 0 0 1 1 1 0 FOXP coiled-coil domain Glyco_hydro_2_N PF02837.18 EGG04268.1 - 3.4e-14 53.1 0.9 1.5e-13 51.0 0.1 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EGG04268.1 - 2.4e-12 47.5 0.1 6.3e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 EGG04268.1 - 0.00041 19.6 0.1 0.0015 17.7 0.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain SelR PF01641.18 EGG04269.1 - 1.2e-46 157.7 0.0 1.4e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 SelR domain TMCO5 PF14992.6 EGG04271.1 - 0.012 15.2 3.8 0.012 15.2 3.8 1.7 2 0 0 2 2 2 0 TMCO5 family PdaC PF13739.6 EGG04271.1 - 0.082 13.9 1.4 0.3 12.1 0.1 2.3 2 0 0 2 2 2 0 Deacetylase PdaC Syntaxin-6_N PF09177.11 EGG04271.1 - 0.97 10.0 5.1 0.22 12.1 0.7 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal GAGE PF05831.11 EGG04272.1 - 0.061 13.9 0.6 0.061 13.9 0.6 2.5 2 0 0 2 2 2 0 GAGE protein MCM6_C PF18263.1 EGG04272.1 - 0.1 12.8 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain NCD1 PF04904.13 EGG04272.1 - 0.18 11.9 0.0 7.4 6.7 0.0 2.4 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) MIP-T3_C PF17749.1 EGG04272.1 - 0.92 9.5 4.7 0.43 10.5 0.2 2.6 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Not3 PF04065.15 EGG04272.1 - 1.2 8.5 9.3 0.31 10.4 0.1 2.9 4 0 0 4 4 4 0 Not1 N-terminal domain, CCR4-Not complex component SesA PF17107.5 EGG04273.1 - 0.1 12.8 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3021 PF11457.8 EGG04274.1 - 0.015 15.7 0.2 0.017 15.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DUF2569 PF10754.9 EGG04274.1 - 0.042 14.3 0.2 0.046 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) DUF4148 PF13663.6 EGG04275.1 - 0.052 13.7 0.1 0.069 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) DUF4148 PF13663.6 EGG04277.1 - 0.069 13.3 0.1 0.091 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) RNA_pol_Rpc4 PF05132.14 EGG04278.1 - 2.8e-31 108.9 0.5 9e-31 107.3 0.0 2.1 1 1 1 2 2 2 1 RNA polymerase III RPC4 FXMRP1_C_core PF12235.8 EGG04278.1 - 2.2 8.9 10.0 4.3 8.0 1.0 2.9 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal TipAS PF07739.13 EGG04279.1 - 0.26 11.8 3.9 1.2 9.7 0.5 2.5 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain TipAS PF07739.13 EGG04280.1 - 0.25 11.9 3.8 1.2 9.7 0.5 2.5 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain FAD_binding_3 PF01494.19 EGG04281.1 - 5.7e-20 71.9 0.0 4.5e-19 68.9 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGG04281.1 - 3.4e-05 24.0 0.0 7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGG04281.1 - 0.00072 20.1 0.0 0.003 18.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGG04281.1 - 0.00073 18.9 0.0 0.014 14.7 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGG04281.1 - 0.0011 18.7 0.0 0.0081 15.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 EGG04281.1 - 0.0034 16.5 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Trp_halogenase PF04820.14 EGG04281.1 - 0.018 13.9 0.0 0.35 9.7 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.24 EGG04281.1 - 0.024 13.7 0.0 1.4 7.9 0.1 2.1 1 1 1 2 2 2 0 FAD binding domain GIDA PF01134.22 EGG04281.1 - 0.072 12.2 0.0 0.11 11.5 0.0 1.3 1 1 0 1 1 1 0 Glucose inhibited division protein A DUF4094 PF13334.6 EGG04281.1 - 0.078 13.4 0.7 0.31 11.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) ApbA PF02558.16 EGG04281.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Flavin_Reduct PF01613.18 EGG04282.1 - 2.2e-23 83.0 0.0 2.9e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Ras PF00071.22 EGG04283.1 - 1.3e-10 41.1 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Ras family CHZ PF09649.10 EGG04283.1 - 0.093 12.2 4.6 0.19 11.2 1.0 2.4 2 0 0 2 2 2 0 Histone chaperone domain CHZ DNA_pol_phi PF04931.13 EGG04284.1 - 0.34 9.0 13.6 0.4 8.7 13.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi MAJIN PF15077.6 EGG04284.1 - 0.91 9.3 4.9 1.1 9.0 4.9 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein ORC6 PF05460.13 EGG04284.1 - 1.4 8.1 13.9 1.6 7.9 13.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PBP1_TM PF14812.6 EGG04284.1 - 2.7 8.4 18.5 0.16 12.3 10.6 2.2 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FancD2 PF14631.6 EGG04287.1 - 5.4 4.3 7.6 5.5 4.2 7.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease HHA PF05321.11 EGG04288.1 - 0.17 12.2 0.1 0.55 10.6 0.1 1.7 2 0 0 2 2 2 0 Haemolysin expression modulating protein API5 PF05918.11 EGG04288.1 - 0.18 10.6 4.3 0.32 9.8 4.3 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF3537 PF12056.8 EGG04291.1 - 0.036 12.9 1.0 0.048 12.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) SVWC PF15430.6 EGG04292.1 - 0.061 13.6 0.3 0.087 13.1 0.3 1.2 1 0 0 1 1 1 0 Single domain von Willebrand factor type C CxC1 PF18802.1 EGG04294.1 - 5.3e-31 106.9 1.1 1.2e-30 105.8 1.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG04294.1 - 0.00015 21.9 0.6 0.00037 20.6 0.6 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGG04294.1 - 0.0013 18.3 0.6 0.0035 17.0 0.2 1.9 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase PT PF04886.12 EGG04296.1 - 3.6 7.2 9.7 4.2 7.0 3.9 2.7 2 0 0 2 2 2 0 PT repeat ParE_toxin PF05016.15 EGG04298.1 - 0.04 14.5 0.3 0.066 13.8 0.3 1.3 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE TPR_10 PF13374.6 EGG04299.1 - 0.0052 16.6 0.1 0.0083 16.0 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG04299.1 - 0.044 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat CCDC-167 PF15188.6 EGG04300.1 - 0.0031 17.8 0.7 0.0031 17.8 0.7 2.4 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 167 SesA PF17107.5 EGG04300.1 - 0.13 12.4 1.4 0.7 10.1 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sigma70_ner PF04546.13 EGG04300.1 - 0.17 11.7 2.1 4.2 7.2 0.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region MSP1_C PF07462.11 EGG04302.1 - 0.23 10.1 1.4 0.3 9.7 1.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus F-box-like PF12937.7 EGG04304.1 - 0.0031 17.4 0.2 0.0077 16.1 0.2 1.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EGG04304.1 - 0.074 12.9 1.4 0.24 11.3 1.6 1.7 2 0 0 2 2 2 0 F-box domain Thioredoxin_8 PF13905.6 EGG04305.1 - 0.089 13.1 0.7 0.59 10.5 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin-like KI67R PF08065.12 EGG04305.1 - 1.3 9.6 6.9 0.29 11.7 3.1 1.8 2 0 0 2 2 2 0 KI67R (NUC007) repeat TipAS PF07739.13 EGG04307.1 - 0.038 14.5 3.5 0.21 12.1 0.4 2.5 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain CCDC24 PF15669.5 EGG04307.1 - 5.4 6.8 10.4 5 6.9 3.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Cys_Met_Meta_PP PF01053.20 EGG04308.1 - 2.5e-124 414.7 0.0 3.6e-124 414.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 EGG04308.1 - 5.3e-16 58.6 1.4 2e-15 56.8 1.4 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain Met_gamma_lyase PF06838.11 EGG04308.1 - 5.5e-05 21.9 0.1 0.00013 20.6 0.1 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase GalKase_gal_bdg PF10509.9 EGG04308.1 - 0.00021 20.8 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Aminotran_1_2 PF00155.21 EGG04308.1 - 0.00031 20.0 0.0 0.00061 19.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGG04308.1 - 0.0055 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EGG04308.1 - 0.041 13.2 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase GHMP_kinases_C PF08544.13 EGG04308.1 - 0.15 12.5 2.1 0.35 11.2 0.9 2.4 1 1 1 2 2 2 0 GHMP kinases C terminal DNA_pol_phi PF04931.13 EGG04310.1 - 0.0041 15.3 16.9 0.0064 14.7 16.9 1.3 1 0 0 1 1 1 1 DNA polymerase phi PPP4R2 PF09184.11 EGG04310.1 - 0.012 15.3 11.5 0.019 14.6 11.5 1.3 1 0 0 1 1 1 0 PPP4R2 DUF4636 PF15468.6 EGG04310.1 - 0.02 14.6 4.1 0.039 13.7 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF4611 PF15387.6 EGG04310.1 - 0.053 13.7 10.3 0.41 10.9 10.8 2.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 EGG04310.1 - 0.054 12.8 11.2 0.08 12.3 11.2 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_Rpc4 PF05132.14 EGG04310.1 - 0.089 13.2 3.9 0.14 12.6 3.9 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 EGG04310.1 - 0.11 12.4 10.3 0.16 11.7 10.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 EGG04310.1 - 0.35 10.3 6.8 0.59 9.5 6.8 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) BUD22 PF09073.10 EGG04310.1 - 0.36 10.1 16.2 0.53 9.6 16.2 1.1 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 EGG04310.1 - 0.4 9.6 5.2 0.61 9.0 5.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PglZ PF08665.12 EGG04310.1 - 0.57 10.3 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 PglZ domain Nop14 PF04147.12 EGG04310.1 - 0.63 8.2 20.1 0.9 7.7 20.1 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 EGG04310.1 - 0.7 8.8 20.4 0.21 10.5 17.2 1.7 2 0 0 2 2 2 0 Paf1 Merozoite_SPAM PF07133.11 EGG04310.1 - 0.85 9.6 24.9 1.8 8.5 24.9 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop53 PF07767.11 EGG04310.1 - 1.4 8.2 19.0 2.2 7.6 19.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4820 PF16091.5 EGG04310.1 - 1.7 8.0 7.4 4.7 6.5 7.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Sigma70_ner PF04546.13 EGG04310.1 - 2.5 7.9 13.7 5.1 6.9 13.7 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.16 EGG04310.1 - 2.7 7.1 10.3 4.3 6.5 10.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 EGG04310.1 - 4.3 6.0 9.6 6.4 5.4 9.6 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGG04310.1 - 5.4 5.2 20.3 8.3 4.6 20.3 1.2 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 EGG04310.1 - 6.8 6.8 8.3 12 6.1 8.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nucleopor_Nup85 PF07575.13 EGG04312.1 - 5.3e-74 249.8 9.6 7.1e-73 246.1 9.6 2.3 1 1 0 1 1 1 1 Nup85 Nucleoporin PPP4R2 PF09184.11 EGG04314.1 - 2.2e-08 34.0 0.0 8.8e-08 32.1 0.0 1.9 1 1 0 1 1 1 1 PPP4R2 MNE1 PF13762.6 EGG04315.1 - 0.0091 16.0 0.3 0.013 15.5 0.2 1.3 1 1 0 1 1 1 1 Mitochondrial splicing apparatus component PAN_1 PF00024.26 EGG04316.1 - 0.034 14.1 6.0 0.092 12.7 6.0 1.8 1 1 0 1 1 1 0 PAN domain MIS13 PF08202.11 EGG04317.1 - 0.0083 15.5 0.0 0.009 15.3 0.0 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Isy1 PF06246.12 EGG04317.1 - 0.011 15.3 0.3 0.016 14.8 0.3 1.1 1 0 0 1 1 1 0 Isy1-like splicing family Troponin PF00992.20 EGG04317.1 - 0.024 15.0 0.1 0.033 14.5 0.1 1.1 1 0 0 1 1 1 0 Troponin ZapB PF06005.12 EGG04317.1 - 0.032 14.7 0.2 0.051 14.0 0.2 1.3 1 0 0 1 1 1 0 Cell division protein ZapB Neogenin_C PF06583.12 EGG04317.1 - 0.043 13.7 2.5 0.053 13.4 2.5 1.2 1 0 0 1 1 1 0 Neogenin C-terminus KH_1 PF00013.29 EGG04318.1 - 5.2e-06 26.2 0.1 0.0011 18.7 0.0 2.4 2 0 0 2 2 2 2 KH domain Trp_repressor PF01371.19 EGG04318.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Trp repressor protein DUF5390 PF17365.2 EGG04318.1 - 1 9.6 2.9 1.9 8.8 2.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5390) CDC45 PF02724.14 EGG04319.1 - 0.18 10.1 16.7 0.18 10.1 16.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 EGG04319.1 - 0.49 9.4 17.8 0.59 9.1 17.8 1.1 1 0 0 1 1 1 0 Paf1 DUF913 PF06025.12 EGG04319.1 - 0.79 8.6 3.3 0.73 8.7 3.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 EGG04319.1 - 0.96 8.7 21.7 1.1 8.5 21.7 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 EGG04319.1 - 1.3 7.5 13.1 1.2 7.6 13.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 EGG04319.1 - 1.9 7.1 3.9 2.1 7.0 3.9 1.1 1 0 0 1 1 1 0 Presenilin Na_trans_assoc PF06512.13 EGG04319.1 - 3.4 7.9 15.7 3.8 7.8 15.7 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 EGG04319.1 - 3.7 5.7 31.1 4.1 5.5 31.1 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EGG04319.1 - 4.8 6.4 26.2 7.1 5.9 26.2 1.3 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 EGG04319.1 - 5.3 6.9 24.1 9.4 6.1 24.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region MIP PF00230.20 EGG04320.1 - 1.4e-47 162.4 2.8 1.8e-47 162.0 2.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein TauE PF01925.19 EGG04320.1 - 8.6 5.9 11.4 11 5.5 6.3 2.8 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE DUF1764 PF08576.10 EGG04324.1 - 4.3e-27 94.9 14.6 5.8e-24 84.9 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) DUF4775 PF16001.5 EGG04324.1 - 0.084 12.3 23.0 0.11 12.0 23.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) MDM1 PF15501.6 EGG04324.1 - 0.095 11.8 13.0 0.1 11.7 13.0 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 Vfa1 PF08432.10 EGG04324.1 - 0.13 12.6 17.8 0.16 12.3 17.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Membralin PF09746.9 EGG04324.1 - 0.24 10.4 1.8 0.27 10.3 1.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein FGF-BP1 PF06473.12 EGG04324.1 - 0.27 11.0 13.5 0.38 10.5 13.5 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Presenilin PF01080.17 EGG04324.1 - 0.28 9.9 6.4 0.3 9.8 6.4 1.1 1 0 0 1 1 1 0 Presenilin DUF3807 PF12720.7 EGG04324.1 - 0.32 11.3 15.0 0.39 11.0 15.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RPN2_C PF18004.1 EGG04324.1 - 0.41 10.6 17.1 0.55 10.1 17.1 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PPL5 PF18168.1 EGG04324.1 - 0.44 9.8 10.4 0.56 9.5 10.4 1.2 1 0 0 1 1 1 0 Prim-pol family 5 RR_TM4-6 PF06459.12 EGG04324.1 - 0.83 9.4 12.4 1 9.1 12.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EGG04324.1 - 1.1 9.4 5.3 1.3 9.2 5.3 1.2 1 0 0 1 1 1 0 DDHD domain NARP1 PF12569.8 EGG04324.1 - 1.1 8.0 15.8 1.4 7.7 15.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3530 PF12048.8 EGG04324.1 - 2 7.7 7.3 3.8 6.8 7.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) CLPTM1 PF05602.12 EGG04324.1 - 2.1 7.3 5.9 2.5 7.1 5.9 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Zip PF02535.22 EGG04324.1 - 2.3 7.3 6.2 2.6 7.2 6.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter U79_P34 PF03064.16 EGG04324.1 - 2.5 7.4 16.2 3.6 6.9 16.2 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MAP17 PF15807.5 EGG04324.1 - 2.6 8.3 13.5 4.5 7.5 13.5 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 XRN_M PF17846.1 EGG04324.1 - 3.2 6.6 8.7 3.8 6.4 8.7 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Tim54 PF11711.8 EGG04324.1 - 3.5 6.3 11.2 4.2 6.0 11.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 EGG04324.1 - 3.8 7.9 11.7 5.2 7.5 11.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SLC12 PF03522.15 EGG04324.1 - 4.3 6.3 11.3 5 6.0 11.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 EGG04324.1 - 4.8 6.1 7.8 5.8 5.8 7.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 EGG04324.1 - 5.4 5.7 12.7 6.2 5.5 12.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 EGG04324.1 - 6.5 4.9 12.6 6.8 4.9 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 EGG04324.1 - 6.6 5.2 25.7 7.6 5.0 25.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CobT PF06213.12 EGG04324.1 - 8.1 5.8 13.5 11 5.3 13.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT zf-CCHC PF00098.23 EGG04326.1 - 0.00017 21.5 2.3 0.00034 20.5 2.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGG04326.1 - 0.061 13.2 0.9 0.14 12.0 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 EGG04326.1 - 0.18 11.7 2.1 0.32 10.8 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle F-box-like PF12937.7 EGG04327.1 - 0.00026 20.8 0.1 0.00059 19.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG04327.1 - 0.0089 15.9 0.8 0.021 14.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain Endonuc-FokI_C PF09254.11 EGG04327.1 - 0.05 12.9 0.2 0.071 12.4 0.2 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal KDZ PF18758.1 EGG04331.1 - 3.1e-29 102.2 0.1 5.2e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGG04331.1 - 2e-25 88.9 0.4 4e-25 88.0 0.4 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG04331.1 - 0.0042 17.2 0.2 0.011 15.9 0.2 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases SPT16 PF08644.11 EGG04334.1 - 3.6 7.8 9.6 0.55 10.4 3.5 2.7 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF559 PF04480.12 EGG04335.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF559) SKN1 PF03935.15 EGG04336.1 - 0.0074 14.7 0.0 0.009 14.5 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) G-alpha PF00503.20 EGG04337.1 - 0.00013 21.3 0.8 0.00013 21.3 0.8 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Peptidase_S9 PF00326.21 EGG04338.1 - 1.2e-52 178.5 0.0 2e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EGG04338.1 - 0.013 14.2 0.0 0.4 9.3 0.0 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Asp PF00026.23 EGG04340.1 - 1.6e-22 80.4 0.0 5.7e-22 78.5 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG04340.1 - 4.2e-08 33.6 0.1 0.0016 18.7 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal DNA_pol_B PF00136.21 EGG04342.1 - 5.7e-149 496.7 0.4 1.4e-148 495.4 0.6 1.5 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGG04342.1 - 2.4e-81 273.5 0.0 4.3e-81 272.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGG04342.1 - 2e-18 66.6 5.4 5.1e-18 65.3 5.4 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 EGG04342.1 - 0.00087 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EGG04342.1 - 0.027 14.5 0.4 0.19 11.7 0.4 2.3 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_B_2 PF03175.13 EGG04342.1 - 0.23 10.2 2.8 0.19 10.6 0.5 1.9 2 1 0 2 2 2 0 DNA polymerase type B, organellar and viral C1_1 PF00130.22 EGG04342.1 - 2.8 7.9 6.3 18 5.3 0.8 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_M1 PF01433.20 EGG04343.1 - 0.096 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M1 domain RRP36 PF06102.12 EGG04344.1 - 0.15 12.0 1.7 0.24 11.4 1.7 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF848 PF05852.11 EGG04345.1 - 0.0028 17.8 1.9 0.0044 17.1 1.9 1.3 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) Med9 PF07544.13 EGG04345.1 - 0.054 13.6 1.7 1.3 9.2 1.6 2.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ABC_tran_CTD PF16326.5 EGG04345.1 - 0.085 13.1 7.1 0.27 11.5 3.9 2.6 1 1 2 3 3 3 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 EGG04345.1 - 0.089 12.8 1.9 0.15 12.1 1.9 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 EGG04345.1 - 0.15 12.4 5.0 5.4 7.4 1.6 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlaC_arch PF05377.11 EGG04345.1 - 0.38 11.2 3.9 11 6.5 0.2 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF2175 PF09943.9 EGG04345.1 - 0.52 10.6 3.2 0.54 10.6 2.1 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) FapA PF03961.13 EGG04345.1 - 0.67 8.5 2.3 0.77 8.3 2.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc24 PF08286.11 EGG04345.1 - 6.4 7.1 7.6 28 5.0 3.2 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ParE_toxin PF05016.15 EGG04346.1 - 0.054 14.1 0.0 22 5.7 0.0 3.4 3 0 0 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE DUF4218 PF13960.6 EGG04346.1 - 0.091 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) FYDLN_acid PF09538.10 EGG04346.1 - 7.2 7.4 12.0 0.28 11.9 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Sad1_UNC PF07738.13 EGG04347.1 - 3.2e-28 98.4 0.0 6.2e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF2721 PF11026.8 EGG04347.1 - 0.012 15.5 0.2 0.7 9.8 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) BLOC1_2 PF10046.9 EGG04347.1 - 0.016 15.5 4.5 0.12 12.7 4.4 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C4H2 PF10146.9 EGG04347.1 - 0.13 12.6 2.0 0.19 12.0 2.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Snapin_Pallidin PF14712.6 EGG04347.1 - 4.5 7.8 6.2 5.6 7.5 1.4 2.6 3 0 0 3 3 3 0 Snapin/Pallidin BST2 PF16716.5 EGG04348.1 - 0.0079 16.8 0.2 0.0079 16.8 0.2 3.6 2 1 2 4 4 4 1 Bone marrow stromal antigen 2 BLOC1_2 PF10046.9 EGG04348.1 - 0.017 15.4 15.6 0.062 13.6 0.7 4.0 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lipoprotein_20 PF13942.6 EGG04348.1 - 0.024 14.5 1.0 0.024 14.5 1.0 2.8 2 2 0 2 2 2 0 YfhG lipoprotein DUF842 PF05811.13 EGG04348.1 - 0.029 14.1 6.7 0.077 12.7 6.3 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF724 PF05266.14 EGG04348.1 - 0.049 13.5 14.4 0.11 12.3 0.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Fzo_mitofusin PF04799.13 EGG04348.1 - 0.07 12.7 15.3 0.32 10.5 5.0 3.2 2 1 0 3 3 3 0 fzo-like conserved region RasGAP_C PF03836.15 EGG04348.1 - 0.097 12.8 16.0 3.2 7.9 7.9 3.1 1 1 2 3 3 3 0 RasGAP C-terminus ATG16 PF08614.11 EGG04348.1 - 0.18 12.0 19.3 0.83 9.8 0.6 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 EGG04348.1 - 0.44 11.0 14.2 5.1 7.6 0.9 4.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EGG04348.1 - 0.47 10.5 17.8 0.3 11.1 0.4 3.5 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Med10 PF09748.9 EGG04348.1 - 0.68 9.9 9.4 0.56 10.2 0.3 3.4 2 1 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DNA_pol_delta_4 PF04081.13 EGG04348.1 - 0.74 10.2 4.7 1.1 9.6 1.9 2.2 2 0 0 2 2 2 0 DNA polymerase delta, subunit 4 CENP-H PF05837.12 EGG04348.1 - 0.75 10.2 15.7 0.44 11.0 1.6 2.8 2 1 1 3 3 3 0 Centromere protein H (CENP-H) MscS_porin PF12795.7 EGG04348.1 - 0.86 9.1 18.7 0.6 9.6 13.7 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF2730 PF10805.8 EGG04348.1 - 0.95 9.6 10.4 3.8 7.7 0.2 3.5 3 2 0 3 3 3 0 Protein of unknown function (DUF2730) DHR10 PF18595.1 EGG04348.1 - 1.3 9.1 19.8 0.29 11.2 1.2 3.5 1 1 1 3 3 3 0 Designed helical repeat protein 10 domain ORF6C PF10552.9 EGG04348.1 - 3.7 7.7 7.5 0.4 10.8 0.3 2.8 3 0 0 3 3 3 0 ORF6C domain Syntaxin-6_N PF09177.11 EGG04348.1 - 4.1 8.0 12.7 0.28 11.8 3.3 2.7 3 1 0 3 3 2 0 Syntaxin 6, N-terminal DASH_Dam1 PF08653.10 EGG04348.1 - 4.3 7.2 11.6 4.4 7.2 1.0 3.7 2 1 0 3 3 3 0 DASH complex subunit Dam1 THOC7 PF05615.13 EGG04348.1 - 4.6 7.5 12.9 12 6.2 0.3 3.0 1 1 1 2 2 2 0 Tho complex subunit 7 ADIP PF11559.8 EGG04348.1 - 5 7.2 22.6 0.16 12.1 6.2 3.4 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.22 EGG04348.1 - 6 7.1 11.4 1.7 8.9 1.3 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 EGG04349.1 - 0.41 9.2 2.6 0.67 8.5 2.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Snapin_Pallidin PF14712.6 EGG04349.1 - 2.2 8.7 7.4 14 6.1 0.3 3.5 3 0 0 3 3 3 0 Snapin/Pallidin DHHC PF01529.20 EGG04350.1 - 0.33 11.0 7.9 0.89 9.7 0.1 2.3 1 1 1 2 2 2 0 DHHC palmitoyltransferase Glyco_hydro_7 PF00840.20 EGG04352.1 - 1.8e-176 587.2 6.7 2e-176 587.0 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 RuBisCo_chap_C PF18087.1 EGG04353.1 - 0.085 12.5 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Rubisco Assembly chaperone C-terminal domain Fer2_3 PF13085.6 EGG04354.1 - 1.4e-33 115.1 0.0 2.3e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EGG04354.1 - 3.1e-09 37.3 5.6 3.1e-09 37.3 5.6 2.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGG04354.1 - 1.5e-07 31.8 6.1 1.5e-07 31.8 6.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGG04354.1 - 1.8e-07 31.1 3.5 1.8e-07 31.1 3.5 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EGG04354.1 - 0.0023 18.5 5.2 0.0023 18.5 5.2 2.7 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EGG04354.1 - 0.029 14.3 0.3 0.029 14.3 0.3 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain NUFIP2 PF15293.6 EGG04354.1 - 0.094 11.6 0.5 0.12 11.3 0.5 1.1 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 Fer4_9 PF13187.6 EGG04354.1 - 0.15 12.3 12.0 0.044 14.0 6.8 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Toxin_17 PF08086.11 EGG04357.1 - 0.068 13.5 4.9 0.068 13.5 4.9 1.8 2 0 0 2 2 2 0 Ergtoxin family PCI PF01399.27 EGG04358.1 - 2.3e-13 50.6 1.1 5.2e-13 49.4 1.1 1.6 1 0 0 1 1 1 1 PCI domain Nop52 PF05997.12 EGG04360.1 - 7.8e-72 241.6 0.1 1.4e-71 240.8 0.1 1.4 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DPM2 PF07297.12 EGG04361.1 - 5.9e-28 97.0 0.3 7e-28 96.8 0.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EGG04361.1 - 9.2e-08 32.0 0.2 1.1e-07 31.8 0.2 1.1 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 EGG04361.1 - 0.0035 17.4 0.0 0.0043 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4229 PF14012.6 EGG04361.1 - 0.011 15.9 0.4 0.018 15.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Ni_hydr_CYTB PF01292.20 EGG04361.1 - 0.039 13.5 0.0 0.045 13.3 0.0 1.0 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF5453 PF17534.2 EGG04361.1 - 0.082 12.9 0.0 0.083 12.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) PIRT PF15099.6 EGG04361.1 - 0.13 11.8 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Importin_rep_4 PF18808.1 EGG04363.1 - 3.7e-06 27.1 1.7 0.00051 20.3 0.1 3.1 2 0 0 2 2 2 1 Importin repeat Tax PF02959.16 EGG04363.1 - 0.041 13.3 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 HTLV Tax API5 PF05918.11 EGG04363.1 - 0.12 11.2 2.6 0.17 10.7 0.1 2.4 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) HEAT PF02985.22 EGG04363.1 - 0.6 10.5 5.8 56 4.4 0.0 5.6 6 0 0 6 6 6 0 HEAT repeat DALR_1 PF05746.15 EGG04363.1 - 0.9 9.7 3.9 1.9 8.7 0.0 3.3 4 0 0 4 4 4 0 DALR anticodon binding domain SMC_N PF02463.19 EGG04364.1 - 5.9e-32 110.9 14.5 5.9e-32 110.9 14.5 2.7 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGG04364.1 - 2.5e-25 89.0 0.1 1.1e-24 86.9 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGG04364.1 - 2.6e-05 24.2 0.0 2.6e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGG04364.1 - 0.039 14.2 0.1 0.56 10.5 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF5082 PF16888.5 EGG04364.1 - 0.058 13.7 0.1 0.058 13.7 0.1 6.9 3 1 3 6 6 6 0 Domain of unknown function (DUF5082) DUF3573 PF12097.8 EGG04364.1 - 6.2 5.5 5.6 21 3.8 5.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Mod_r PF07200.13 EGG04365.1 - 2.6e-43 147.6 13.1 3.4e-43 147.2 13.1 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein SapC PF07277.11 EGG04365.1 - 0.02 14.5 0.8 0.037 13.6 0.8 1.4 1 0 0 1 1 1 0 SapC CpxA_peri PF16527.5 EGG04365.1 - 0.32 11.4 2.8 0.45 10.9 1.1 1.8 1 1 1 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain GCM PF03615.15 EGG04367.1 - 0.051 13.4 3.8 0.17 11.8 3.8 1.8 1 0 0 1 1 1 0 GCM motif protein DUF3987 PF13148.6 EGG04367.1 - 0.17 10.9 1.3 0.26 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF572 PF04502.13 EGG04367.1 - 9.2 5.8 19.5 19 4.7 19.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) OSCP PF00213.18 EGG04368.1 - 0.044 13.9 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit BLOC1_2 PF10046.9 EGG04369.1 - 0.021 15.1 0.1 11 6.4 0.0 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SKA1 PF07160.12 EGG04369.1 - 0.052 13.4 0.8 4.9 6.9 0.2 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 BLM10_mid PF16507.5 EGG04369.1 - 0.065 11.9 0.4 0.82 8.2 0.2 2.0 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, mid region Syntaxin_2 PF14523.6 EGG04370.1 - 0.015 15.6 0.2 0.034 14.5 0.2 1.6 1 1 0 1 1 1 0 Syntaxin-like protein BLOC1_2 PF10046.9 EGG04370.1 - 0.036 14.4 2.1 4.8 7.6 0.2 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2852 PF11014.8 EGG04370.1 - 0.24 11.5 0.9 0.45 10.7 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) zf-RING_2 PF13639.6 EGG04371.1 - 8.8e-09 35.6 6.3 1.7e-08 34.7 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGG04371.1 - 1.6e-08 34.3 7.2 2.8e-08 33.5 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG04371.1 - 1.6e-08 34.3 5.5 2.5e-08 33.7 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG04371.1 - 2.4e-08 33.8 2.9 2.4e-08 33.8 2.9 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG04371.1 - 2.4e-07 30.5 8.1 9.5e-07 28.6 8.2 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG04371.1 - 4.1e-07 29.9 6.5 7.4e-07 29.0 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGG04371.1 - 8.7e-05 22.3 4.1 0.0002 21.2 4.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGG04371.1 - 9.7e-05 22.5 7.6 0.00019 21.5 7.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.20 EGG04371.1 - 0.00032 20.4 3.8 0.00058 19.6 3.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EGG04371.1 - 0.003 17.3 5.3 0.0059 16.4 2.4 2.4 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 EGG04371.1 - 0.011 16.0 2.8 0.026 14.8 2.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGG04371.1 - 0.019 15.0 1.7 0.035 14.2 1.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SFTA2 PF15210.6 EGG04371.1 - 0.026 14.4 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 Surfactant-associated protein 2 FYVE PF01363.21 EGG04371.1 - 0.047 13.8 3.0 0.099 12.8 3.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_11 PF17123.5 EGG04371.1 - 0.58 10.0 7.3 0.49 10.2 4.3 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_6 PF14835.6 EGG04371.1 - 0.65 9.9 2.9 3.4 7.6 2.8 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EGG04371.1 - 0.68 9.8 4.1 1.6 8.6 4.1 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TerY_C PF15616.6 EGG04371.1 - 2 8.6 4.0 4.4 7.4 4.0 1.5 1 1 0 1 1 1 0 TerY-C metal binding domain Auto_anti-p27 PF06677.12 EGG04371.1 - 2.2 8.5 7.6 11 6.3 0.2 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) p450 PF00067.22 EGG04372.1 - 3.2e-45 154.8 0.0 5.1e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FXMRP1_C_core PF12235.8 EGG04374.1 - 6.8 7.3 11.7 0.44 11.2 5.1 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal 4HBT_2 PF13279.6 EGG04375.1 - 1.2e-10 41.9 0.0 1.9e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Ig_GlcNase PF18368.1 EGG04375.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Exo-beta-D-glucosaminidase Ig-fold domain UPF0160 PF03690.13 EGG04376.1 - 4.9e-132 440.4 0.0 5.6e-132 440.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Pkinase PF00069.25 EGG04377.1 - 1.3e-06 28.0 0.0 1.4e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG04377.1 - 0.00033 20.0 0.0 0.00035 19.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EGG04377.1 - 0.043 13.4 0.0 0.044 13.4 0.0 1.0 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 NUDE_C PF04880.13 EGG04378.1 - 0.32 11.5 11.2 0.071 13.6 3.5 2.2 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region Borrelia_P83 PF05262.11 EGG04378.1 - 4.5 5.6 11.5 6.2 5.2 11.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3844 PF12955.7 EGG04382.1 - 0.063 13.4 2.6 0.14 12.3 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) Sec5 PF15469.6 EGG04385.1 - 1.1e-54 185.2 0.0 1.1e-53 181.9 0.0 2.4 2 0 0 2 2 2 1 Exocyst complex component Sec5 DUF4778 PF16008.5 EGG04385.1 - 0.075 13.1 0.1 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) zf-CCHC PF00098.23 EGG04386.1 - 0.0035 17.4 1.0 0.0065 16.5 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle cobW PF02492.19 EGG04387.1 - 1e-26 93.6 0.0 1.2e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EGG04387.1 - 0.0026 18.1 0.1 0.0039 17.6 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EGG04387.1 - 0.0031 17.6 0.1 0.0042 17.1 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EGG04387.1 - 0.0034 17.7 0.0 0.0045 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGG04387.1 - 0.0037 17.0 0.1 0.0086 15.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 EGG04387.1 - 0.01 15.8 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TsaE PF02367.17 EGG04387.1 - 0.013 15.5 0.1 0.025 14.6 0.1 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EGG04387.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 EGG04387.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 EGG04387.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EGG04387.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 EGG04387.1 - 0.021 14.7 0.2 0.049 13.5 0.2 1.6 1 1 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 EGG04387.1 - 0.022 14.9 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGG04387.1 - 0.023 15.2 0.0 0.03 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGG04387.1 - 0.024 15.1 0.0 0.028 14.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter dNK PF01712.19 EGG04387.1 - 0.028 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_15 PF13175.6 EGG04387.1 - 0.044 13.5 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EGG04387.1 - 0.066 12.4 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 EGG04387.1 - 0.076 13.1 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGG04387.1 - 0.078 12.5 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EGG04387.1 - 0.14 12.0 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 NTPase Ras PF00071.22 EGG04387.1 - 0.16 11.6 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 Ras family DEAD PF00270.29 EGG04388.1 - 6.1e-43 146.6 0.0 1e-42 145.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG04388.1 - 4.4e-25 88.2 0.3 1.7e-24 86.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG04388.1 - 0.059 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-AN1 PF01428.16 EGG04390.1 - 2.7e-10 40.2 5.7 5.2e-10 39.3 5.7 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EGG04390.1 - 0.06 13.7 5.0 0.11 12.9 5.0 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain DHDPS PF00701.22 EGG04392.1 - 0.068 11.9 0.1 0.13 10.9 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family TFIIF_alpha PF05793.12 EGG04395.1 - 7.7e-11 41.3 31.8 7.7e-11 41.3 31.8 3.5 1 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ABC2_membrane PF01061.24 EGG04396.1 - 3e-64 216.3 46.6 8.6e-40 136.4 14.9 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EGG04396.1 - 3.6e-32 111.7 0.0 1.6e-18 67.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGG04396.1 - 2.4e-16 59.4 0.1 1.3e-15 57.1 0.0 2.3 2 0 0 2 2 2 1 CDR ABC transporter AAA_16 PF13191.6 EGG04396.1 - 3e-05 24.5 0.6 0.02 15.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EGG04396.1 - 4e-05 23.6 0.1 0.05 13.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGG04396.1 - 0.00024 21.1 0.8 0.00049 20.0 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EGG04396.1 - 0.0039 17.5 0.2 0.52 10.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EGG04396.1 - 0.03 13.9 1.5 0.046 13.3 0.1 2.0 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 EGG04396.1 - 0.047 13.4 0.0 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGG04396.1 - 0.068 12.9 1.4 0.12 12.1 0.3 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGG04396.1 - 0.088 12.9 0.5 0.56 10.3 0.1 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.6 EGG04396.1 - 0.11 12.9 0.3 18 5.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGG04396.1 - 0.11 13.0 0.3 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NOA36 PF06524.12 EGG04396.1 - 0.12 11.7 9.6 0.21 10.9 9.6 1.3 1 0 0 1 1 1 0 NOA36 protein NACHT PF05729.12 EGG04396.1 - 0.15 12.0 0.3 0.91 9.4 0.1 2.2 2 0 0 2 2 2 0 NACHT domain CDC45 PF02724.14 EGG04396.1 - 0.28 9.4 6.8 0.45 8.8 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.12 EGG04396.1 - 0.72 9.8 3.1 1.4 8.9 3.1 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit FAM176 PF14851.6 EGG04396.1 - 2.5 7.7 9.5 8.3 6.1 8.7 2.0 2 0 0 2 2 2 0 FAM176 family DUF21 PF01595.20 EGG04396.1 - 6.9 6.3 9.8 0.42 10.3 0.1 3.1 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain Radial_spoke PF04712.12 EGG04396.1 - 7.9 5.3 7.7 13 4.6 7.7 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Frag1 PF10277.9 EGG04397.1 - 3e-37 128.3 18.1 3.5e-37 128.1 18.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Prominin PF05478.11 EGG04397.1 - 0.84 7.5 4.1 1.3 6.9 4.1 1.2 1 0 0 1 1 1 0 Prominin TMEM173 PF15009.6 EGG04397.1 - 1 8.4 3.0 1 8.5 1.9 1.6 1 1 1 2 2 2 0 Transmembrane protein 173 Macoilin PF09726.9 EGG04397.1 - 1.4 7.4 2.8 2 6.8 2.8 1.2 1 0 0 1 1 1 0 Macoilin family DUF2663 PF10864.8 EGG04397.1 - 4.7 7.6 6.5 22 5.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) DUF3810 PF12725.7 EGG04397.1 - 6 6.1 6.5 8.4 5.6 3.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Mito_carr PF00153.27 EGG04398.1 - 3.1e-48 161.6 5.9 1.5e-15 56.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NPV_P10 PF05531.12 EGG04402.1 - 0.056 13.9 0.1 0.056 13.9 0.1 3.1 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein gag-asp_proteas PF13975.6 EGG04403.1 - 0.19 12.3 0.0 9.9 6.8 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease PAPS_reduct PF01507.19 EGG04404.1 - 2e-38 132.1 0.0 2.9e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Bax1-I PF01027.20 EGG04405.1 - 1.7e-34 119.5 11.8 2e-34 119.3 11.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Inhibitor_I9 PF05922.16 EGG04406.1 - 0.0019 18.9 0.0 0.0019 18.9 0.0 3.0 3 1 0 3 3 3 1 Peptidase inhibitor I9 LIG3_BRCT PF16759.5 EGG04406.1 - 0.48 10.8 2.5 0.43 10.9 0.2 2.1 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain TP_methylase PF00590.20 EGG04407.1 - 6.6e-17 62.2 0.0 9.3e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TPR_MLP1_2 PF07926.12 EGG04410.1 - 0.017 15.2 3.2 0.033 14.3 3.2 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein SKA1 PF07160.12 EGG04410.1 - 0.067 13.0 1.8 0.1 12.4 1.8 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Jnk-SapK_ap_N PF09744.9 EGG04410.1 - 0.088 13.0 3.6 0.17 12.1 3.6 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ZapB PF06005.12 EGG04410.1 - 0.15 12.5 6.0 0.29 11.6 6.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF349 PF03993.12 EGG04410.1 - 0.16 12.2 2.2 0.7 10.2 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Adaptin_binding PF10199.9 EGG04410.1 - 0.77 10.4 4.8 0.97 10.1 2.3 2.1 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 CPSF73-100_C PF11718.8 EGG04411.1 - 2.4 7.7 7.8 3.3 7.2 7.4 1.4 1 1 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Secretin_N_2 PF07655.13 EGG04411.1 - 3.5 8.2 15.1 0.33 11.5 4.9 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Peptidase_M48 PF01435.18 EGG04413.1 - 2.5e-33 115.5 0.0 5.6e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 COesterase PF00135.28 EGG04414.1 - 4e-76 256.9 0.0 5.6e-52 177.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family VitD-bind_III PF09164.10 EGG04414.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Vitamin D binding protein, domain III COesterase PF00135.28 EGG04415.1 - 1.2e-78 265.2 0.0 1.6e-78 264.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EGG04415.1 - 0.062 12.8 0.2 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGG04415.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold RNase_T PF00929.24 EGG04416.1 - 3.5e-06 27.7 0.0 1.1e-05 26.0 0.0 1.9 1 1 0 1 1 1 1 Exonuclease Itfg2 PF15907.5 EGG04418.1 - 3 6.8 7.7 0.19 10.7 2.8 1.5 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 CPBP PF02517.16 EGG04419.1 - 1.7e-15 57.1 7.4 3.5e-15 56.1 6.7 2.2 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease YqzM PF14141.6 EGG04419.1 - 0.4 10.8 4.9 1.1 9.3 4.9 1.8 1 0 0 1 1 1 0 YqzM-like protein CAF1 PF04857.20 EGG04420.1 - 3.3e-18 65.9 0.0 2.5e-08 33.5 0.0 2.4 2 1 0 2 2 2 2 CAF1 family ribonuclease PsbR PF04725.12 EGG04420.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR GPI-anchored PF10342.9 EGG04421.1 - 7.7e-11 42.6 1.8 7.7e-11 42.6 1.8 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family LCAT PF02450.15 EGG04422.1 - 2.3e-85 287.1 0.0 2.8e-85 286.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lactonase PF10282.9 EGG04423.1 - 1.7e-68 231.4 0.0 2e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 EGG04423.1 - 0.034 14.1 0.6 9.9 6.2 0.1 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TPX2 PF06886.11 EGG04424.1 - 6.9e-12 45.4 12.9 7.8e-12 45.2 12.9 1.0 1 0 0 1 1 1 1 Targeting protein for Xklp2 (TPX2) DUF501 PF04417.12 EGG04424.1 - 0.22 11.3 1.6 0.26 11.1 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Peptidase_S8 PF00082.22 EGG04425.1 - 1.1e-33 116.8 12.3 2e-33 115.9 12.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGG04425.1 - 1.6e-11 44.7 0.0 3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 IGPS PF00218.21 EGG04426.1 - 4.9e-78 261.8 0.0 9.8e-78 260.8 0.0 1.5 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EGG04426.1 - 9.6e-47 159.3 0.0 5.1e-40 137.3 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EGG04426.1 - 1.8e-40 138.7 0.0 4.8e-40 137.4 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGG04426.1 - 0.00028 20.7 1.0 0.0017 18.2 1.0 2.2 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 EGG04426.1 - 0.022 14.5 0.6 0.4 10.5 0.1 2.4 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain ThuA PF06283.11 EGG04426.1 - 0.09 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Trehalose utilisation Alpha-amylase_C PF02806.18 EGG04427.1 - 8e-23 80.7 0.1 1.8e-22 79.6 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EGG04427.1 - 2.2e-17 63.2 0.0 5.4e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EGG04427.1 - 8.2e-13 48.6 0.1 1.8e-10 40.9 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain AbiEi_3 PF11459.8 EGG04427.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Alg6_Alg8 PF03155.15 EGG04429.1 - 5.1e-164 546.8 23.1 5.9e-164 546.6 23.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF5516 PF17637.2 EGG04429.1 - 0.062 13.0 0.5 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5516) FSH1 PF03959.13 EGG04430.1 - 2.9e-38 131.7 0.0 3.3e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF3292 PF11696.8 EGG04431.1 - 2e-06 26.5 0.2 0.0027 16.1 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3292) PRT_C PF08372.10 EGG04431.1 - 0.0026 17.5 0.9 0.013 15.2 0.1 2.3 1 1 1 2 2 2 1 Plant phosphoribosyltransferase C-terminal KMP11 PF03037.16 EGG04431.1 - 0.03 15.1 0.4 9.4 7.1 0.0 2.8 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 YMF19 PF02326.15 EGG04431.1 - 8 7.3 8.5 7.5 7.4 1.1 3.8 2 1 1 3 3 3 0 Plant ATP synthase F0 Iso_dh PF00180.20 EGG04433.1 - 9.8e-100 334.1 0.0 1.2e-99 333.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AvrL567-A PF11529.8 EGG04434.1 - 1.9e-19 70.1 0.0 2.4e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Melampsora lini avirulence protein AvrL567-A CRAL_TRIO PF00650.20 EGG04435.1 - 4.7e-34 117.4 0.1 8e-34 116.7 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGG04435.1 - 6.4e-11 42.3 0.1 2.3e-09 37.3 0.0 2.7 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGG04435.1 - 0.015 15.5 0.1 0.031 14.4 0.1 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Pyridox_oxase_2 PF12766.7 EGG04436.1 - 2.6e-16 60.1 0.0 4.2e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CDC14 PF08045.11 EGG04437.1 - 2.6e-20 72.7 9.6 3.1e-20 72.5 5.3 2.6 2 0 0 2 2 2 2 Cell division control protein 14, SIN component EST1_DNA_bind PF10373.9 EGG04439.1 - 0.25 10.8 1.8 0.29 10.6 0.7 1.5 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain GWT1 PF06423.12 EGG04439.1 - 2.8 8.1 6.0 2 8.5 0.7 2.3 1 1 1 2 2 2 0 GWT1 PPC PF04151.15 EGG04440.1 - 0.33 12.1 2.1 0.89 10.7 2.1 1.8 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Mitoc_mL59 PF18126.1 EGG04440.1 - 2.6 8.4 8.2 13 6.1 8.2 2.0 1 1 0 1 1 1 0 Mitochondrial ribosomal protein mL59 CotH PF08757.11 EGG04442.1 - 0.035 13.6 0.2 0.045 13.3 0.2 1.2 1 0 0 1 1 1 0 CotH kinase protein Retrotran_gag_2 PF14223.6 EGG04442.1 - 0.1 12.3 0.1 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type ATPase_2 PF01637.18 EGG04445.1 - 0.011 15.6 0.0 0.43 10.4 0.0 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RNA12 PF10443.9 EGG04445.1 - 0.019 13.7 1.1 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 RNA12 protein RdRP PF05183.12 EGG04446.1 - 3.9e-69 233.8 0.0 4.8e-67 226.9 0.0 2.1 1 1 0 1 1 1 1 RNA dependent RNA polymerase MS_channel PF00924.18 EGG04448.1 - 6.6e-21 74.8 1.2 1.1e-20 74.0 1.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 EGG04448.1 - 0.0017 18.1 0.1 0.0017 18.1 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGG04448.1 - 0.0031 17.0 0.1 0.0031 17.0 0.1 2.8 2 1 1 3 3 3 1 EF hand EF-hand_5 PF13202.6 EGG04448.1 - 0.059 12.9 0.2 0.059 12.9 0.2 2.1 2 0 0 2 2 2 0 EF hand F-box-like_2 PF13013.6 EGG04450.1 - 0.013 15.4 1.1 0.3 11.1 0.0 2.9 3 0 0 3 3 3 0 F-box-like domain F-box-like_2 PF13013.6 EGG04451.1 - 0.052 13.5 0.1 0.52 10.3 0.0 2.4 2 0 0 2 2 2 0 F-box-like domain Senescence PF06911.12 EGG04452.1 - 7.6e-47 160.0 9.4 2.5e-46 158.3 8.1 2.2 2 0 0 2 2 2 1 Senescence-associated protein ExbD PF02472.16 EGG04452.1 - 0.025 14.8 0.7 0.083 13.1 0.0 2.2 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR AFG1_ATPase PF03969.16 EGG04455.1 - 3.1e-93 312.5 0.0 1.3e-91 307.2 0.0 2.1 2 0 0 2 2 2 1 AFG1-like ATPase AAA_22 PF13401.6 EGG04455.1 - 0.0015 18.8 0.0 0.0074 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGG04455.1 - 0.0055 17.1 0.1 0.15 12.5 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EGG04455.1 - 0.024 15.1 0.0 0.18 12.2 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGG04455.1 - 0.07 13.1 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Colicin_D PF11429.8 EGG04456.1 - 0.092 13.2 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Colicin D KdpD PF02702.17 EGG04459.1 - 0.046 13.2 0.1 0.065 12.7 0.1 1.1 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain DUF2069 PF09842.9 EGG04460.1 - 0.097 12.9 1.1 0.18 12.0 1.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) Bestrophin PF01062.21 EGG04461.1 - 1.5e-38 132.9 0.0 1.7e-18 67.1 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel TRAPP PF04051.16 EGG04462.1 - 6.7e-34 116.7 0.0 8e-34 116.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.10 EGG04462.1 - 0.13 12.6 0.0 2.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Nrap_D5 PF17406.2 EGG04463.1 - 0.018 14.8 0.4 6.6 6.5 0.2 2.7 2 1 0 2 2 2 0 Nrap protein PAP/OAS1-like domain 5 Abhydrolase_3 PF07859.13 EGG04464.1 - 3e-06 27.2 0.0 4.2e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 EGG04464.1 - 0.00024 20.8 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 EGG04464.1 - 0.0016 17.7 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGG04464.1 - 0.0024 17.4 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 EGG04464.1 - 0.0064 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.20 EGG04464.1 - 0.0086 15.7 0.5 1.8 8.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 EGG04464.1 - 0.017 15.0 0.0 0.058 13.3 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 EGG04464.1 - 0.019 15.6 0.0 0.024 15.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 EGG04464.1 - 0.032 13.1 0.0 0.19 10.6 0.0 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase DUF1749 PF08538.10 EGG04464.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) DUF2235 PF09994.9 EGG04464.1 - 0.081 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Lipase_3 PF01764.25 EGG04464.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) TPR_11 PF13414.6 EGG04466.1 - 0.071 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 TPR repeat Lactamase_B_2 PF12706.7 EGG04469.1 - 2.1e-25 89.4 0.0 4.5e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGG04469.1 - 0.0057 16.7 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EGG04469.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Cyclin_N PF00134.23 EGG04473.1 - 1.2e-09 38.0 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGG04473.1 - 1.6e-05 25.3 0.2 1.6e-05 25.3 0.2 2.3 2 1 0 2 2 2 1 Cyclin PMT_2 PF13231.6 EGG04473.1 - 0.16 12.2 0.1 0.22 11.7 0.1 1.1 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase MutL_C PF08676.11 EGG04475.1 - 2.4e-21 76.0 0.1 1.1e-20 73.9 0.0 2.1 3 1 0 3 3 3 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EGG04475.1 - 6.7e-12 45.4 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGG04475.1 - 3e-06 27.7 0.0 5.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sporozoite_P67 PF05642.11 EGG04476.1 - 0.0012 17.1 2.6 0.0012 17.1 2.6 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF4611 PF15387.6 EGG04476.1 - 0.0053 16.9 0.1 0.009 16.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 EGG04476.1 - 0.029 14.7 5.7 0.047 14.1 5.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIF_alpha PF05793.12 EGG04476.1 - 0.085 11.4 12.7 0.12 11.0 12.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FRQ PF09421.10 EGG04476.1 - 0.16 10.0 8.9 0.2 9.7 8.9 1.0 1 0 0 1 1 1 0 Frequency clock protein NOA36 PF06524.12 EGG04476.1 - 0.27 10.5 10.1 0.41 9.9 5.4 2.0 2 0 0 2 2 2 0 NOA36 protein CENP-B_dimeris PF09026.10 EGG04476.1 - 0.4 11.1 9.4 0.66 10.4 9.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 EGG04476.1 - 0.47 10.5 1.7 0.68 10.0 1.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 EGG04476.1 - 0.58 9.8 2.3 0.85 9.3 2.3 1.2 1 0 0 1 1 1 0 FAM176 family Apt1 PF10351.9 EGG04476.1 - 2.9 6.6 4.4 3.6 6.3 4.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 EGG04476.1 - 3.5 5.8 4.4 4.7 5.4 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 EGG04476.1 - 6 6.5 11.9 8.9 6.0 11.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EGG04476.1 - 8.8 4.3 7.2 13 3.7 7.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi DEAD PF00270.29 EGG04477.1 - 3.1e-47 160.6 0.0 4.9e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG04477.1 - 1.7e-20 73.5 0.0 1.3e-18 67.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG04477.1 - 1.1e-06 28.7 0.0 1.8e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EGG04477.1 - 0.0045 16.3 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain AAA_22 PF13401.6 EGG04477.1 - 0.015 15.5 0.0 0.042 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGG04477.1 - 0.039 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ANAPC4_WD40 PF12894.7 EGG04478.1 - 1.1e-09 38.5 0.0 0.066 13.5 0.1 5.1 3 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG04478.1 - 1.2e-07 32.2 3.0 0.52 11.3 0.1 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.11 EGG04478.1 - 0.0097 15.8 0.3 0.29 11.0 0.1 3.1 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WDCP PF15390.6 EGG04478.1 - 0.044 12.2 0.1 0.2 10.0 0.1 1.9 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family SET PF00856.28 EGG04480.1 - 3.4e-08 34.0 0.0 1.5e-07 32.0 0.0 2.1 1 1 0 1 1 1 1 SET domain Alpha_kinase PF02816.18 EGG04481.1 - 2.1e-08 34.5 0.0 4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family DSS1_SEM1 PF05160.13 EGG04482.1 - 1.2e-21 76.6 10.6 1.8e-21 76.0 10.6 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family Abhydrolase_3 PF07859.13 EGG04483.1 - 8.4e-44 150.0 0.0 1.5e-33 116.4 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGG04483.1 - 2.8e-09 36.3 0.0 1.4e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase Glyco_hydro_18 PF00704.28 EGG04484.1 - 4.4e-60 204.0 0.1 5.2e-60 203.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 EGG04484.1 - 0.037 13.5 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Latrotoxin_C PF15658.6 EGG04484.1 - 0.19 11.5 0.0 0.59 9.9 0.0 1.8 2 0 0 2 2 2 0 Latrotoxin C-terminal domain DUF4648 PF15505.6 EGG04485.1 - 0.16 12.8 2.1 1.3 10.0 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4648) ketoacyl-synt PF00109.26 EGG04485.1 - 0.5 9.9 2.5 2.5 7.6 0.7 1.9 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ABC_tran PF00005.27 EGG04487.1 - 6.2e-32 111.0 0.0 1.6e-22 80.5 0.0 2.2 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGG04487.1 - 1.7e-07 30.9 0.1 0.1 12.0 0.0 3.1 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGG04487.1 - 4.8e-06 26.6 9.2 0.013 15.3 0.5 3.3 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGG04487.1 - 8.6e-05 22.7 0.0 0.012 15.8 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGG04487.1 - 0.00068 19.3 0.3 0.0046 16.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG04487.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 EGG04487.1 - 0.22 10.5 0.0 0.43 9.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_15 PF13175.6 EGG04487.1 - 2.3 7.9 7.7 3.3 7.3 0.6 2.4 2 1 0 2 2 2 0 AAA ATPase domain HsbA PF12296.8 EGG04489.1 - 2.8e-06 27.8 0.1 4.4e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A C166 PF17615.2 EGG04489.1 - 1.1 9.4 6.1 0.19 11.8 0.5 2.3 1 1 2 3 3 3 0 Family of unknown function MFS_1 PF07690.16 EGG04492.1 - 1.3e-27 96.6 22.3 1.9e-26 92.8 22.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Glycohydro_20b2 PF14845.6 EGG04493.1 - 0.009 16.7 0.0 0.011 16.4 0.0 1.1 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20 PF00728.22 EGG04494.1 - 1.7e-48 165.8 0.4 2e-48 165.6 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain EF-hand_6 PF13405.6 EGG04495.1 - 2.1e-18 64.6 0.2 0.00016 21.4 0.0 4.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 EGG04495.1 - 3.5e-18 63.7 0.9 5.3e-05 22.5 0.1 4.7 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGG04495.1 - 8e-17 61.5 0.0 1.8e-07 31.5 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG04495.1 - 2.5e-15 55.2 0.1 0.0014 18.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGG04495.1 - 7.8e-13 48.1 1.4 9.8e-07 28.5 0.1 4.6 3 2 1 4 4 4 4 EF-hand domain pair DUF659 PF04937.15 EGG04496.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) ADH_zinc_N_2 PF13602.6 EGG04498.1 - 0.0007 20.7 0.0 0.0014 19.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG04498.1 - 0.025 14.5 0.0 0.09 12.7 0.0 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGG04498.1 - 0.036 14.1 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF4779 PF16009.5 EGG04499.1 - 0.097 12.7 8.6 0.18 11.9 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4779) RIBIOP_C PF04950.12 EGG04499.1 - 0.34 10.3 6.3 0.67 9.3 6.3 1.4 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal FAM219A PF15260.6 EGG04499.1 - 0.87 10.0 6.1 0.4 11.1 0.2 2.7 1 1 2 3 3 3 0 Protein family FAM219A DNA_pol3_delta2 PF13177.6 EGG04500.1 - 6.7e-12 45.5 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 EGG04500.1 - 0.00073 19.9 0.1 0.0058 17.0 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 EGG04500.1 - 0.0036 17.7 0.1 0.012 16.0 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG04500.1 - 0.026 14.9 0.3 0.066 13.6 0.1 1.8 2 1 0 2 2 2 0 AAA ATPase domain DUF4780 PF16012.5 EGG04500.1 - 0.069 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) Glyco_transf_25 PF01755.17 EGG04501.1 - 3.7e-14 53.1 0.1 1.3e-08 34.9 0.0 3.1 3 0 0 3 3 3 3 Glycosyltransferase family 25 (LPS biosynthesis protein) MBOAT PF03062.19 EGG04503.1 - 3.1e-33 115.6 8.0 5.6e-33 114.7 7.9 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Iso_dh PF00180.20 EGG04504.1 - 3.9e-82 276.2 0.0 4.9e-82 275.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4764 PF15961.5 EGG04505.1 - 0.36 9.5 4.0 0.53 8.9 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) Med26 PF08711.11 EGG04507.1 - 0.002 18.1 0.1 0.0074 16.3 0.1 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain zf-CCCH_2 PF14608.6 EGG04507.1 - 0.022 15.2 0.4 0.052 14.0 0.4 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DELLA PF12041.8 EGG04507.1 - 0.073 13.0 0.1 6.6 6.7 0.0 2.8 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Egh16-like PF11327.8 EGG04508.1 - 2.3e-20 73.8 1.4 2.3e-20 73.8 1.4 1.5 2 0 0 2 2 2 1 Egh16-like virulence factor Arf PF00025.21 EGG04509.1 - 6.3e-66 221.1 0.2 7e-66 221.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGG04509.1 - 1.3e-13 50.9 0.8 1.1e-07 31.3 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EGG04509.1 - 1.6e-12 47.7 0.0 2.2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGG04509.1 - 1.6e-11 44.0 0.0 2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGG04509.1 - 2.8e-11 43.3 0.0 3.4e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGG04509.1 - 4.2e-09 36.1 0.0 4.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG04509.1 - 4.4e-08 33.2 0.0 6.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG04509.1 - 4.3e-05 23.1 0.0 0.0014 18.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 EGG04509.1 - 0.0054 16.3 0.1 0.12 12.0 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 EGG04509.1 - 0.012 15.1 0.1 0.037 13.6 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 EGG04509.1 - 0.017 14.5 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_18 PF13238.6 EGG04509.1 - 0.045 14.3 0.1 0.14 12.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGG04509.1 - 0.046 14.0 0.1 0.092 13.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGG04509.1 - 0.067 12.9 0.1 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 EGG04509.1 - 0.086 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein CdhD PF03599.16 EGG04509.1 - 0.12 11.1 0.0 0.26 10.0 0.0 1.4 1 1 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit GMC_oxred_N PF00732.19 EGG04510.1 - 3.9e-53 180.7 0.0 5.1e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGG04510.1 - 4.4e-34 118.1 0.0 7.6e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EGG04510.1 - 8.3e-06 26.0 0.2 3.4e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG04510.1 - 6.4e-05 22.3 0.1 0.00011 21.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGG04510.1 - 0.0001 21.5 0.1 0.00074 18.7 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EGG04510.1 - 0.0001 21.6 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EGG04510.1 - 0.00024 20.3 0.9 0.00038 19.6 0.2 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 EGG04510.1 - 0.00052 19.7 0.2 0.0036 16.9 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGG04510.1 - 0.0065 15.8 0.6 0.013 14.8 0.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGG04510.1 - 0.039 12.7 0.1 0.063 12.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EGG04510.1 - 0.08 12.9 0.2 0.26 11.2 0.3 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glyco_hydro_26 PF02156.15 EGG04511.1 - 1.1e-16 61.2 1.9 1.5e-16 60.7 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 TatD_DNase PF01026.21 EGG04513.1 - 1.7e-50 171.8 0.0 2.2e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 EGG04513.1 - 0.069 12.9 0.1 0.92 9.2 0.0 2.7 3 1 0 3 3 3 0 Amidohydrolase RPN6_N PF18055.1 EGG04514.1 - 0.04 14.3 0.0 0.08 13.3 0.0 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF445 PF04286.12 EGG04514.1 - 0.084 12.7 0.6 0.16 11.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF445) ApbA_C PF08546.11 EGG04515.1 - 0.066 13.4 0.2 0.11 12.8 0.2 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Glyco_transf_49 PF13896.6 EGG04516.1 - 3e-60 204.3 3.1 8.6e-49 166.6 0.3 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_hydro_20 PF00728.22 EGG04517.1 - 4.9e-85 286.0 0.0 6.6e-85 285.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGG04517.1 - 3.7e-14 53.6 0.3 2.1e-12 47.8 0.0 3.2 3 1 0 3 3 3 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGG04517.1 - 4.1e-05 24.4 0.1 0.0061 17.3 0.0 3.3 2 1 1 3 3 3 1 Glycosyl hydrolase family 20, domain 2 Neugrin PF06413.11 EGG04520.1 - 1.8e-08 34.7 0.9 2.6e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 EGG04520.1 - 0.00024 21.3 0.4 0.00046 20.4 0.4 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 MarR_2 PF12802.7 EGG04520.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 MarR family Cpn60_TCP1 PF00118.24 EGG04521.1 - 1.6e-143 478.9 0.7 1.8e-143 478.7 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF356 PF04009.12 EGG04521.1 - 0.08 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF356) DAHP_snth_FXD PF18152.1 EGG04522.1 - 0.042 13.7 0.2 0.078 12.8 0.2 1.4 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain Tom7 PF08038.12 EGG04525.1 - 3.1e-16 58.7 0.0 3.7e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 TOM7 family Fe-ADH PF00465.19 EGG04526.1 - 4e-92 308.8 0.0 4.9e-92 308.5 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGG04526.1 - 4.3e-14 52.8 0.0 8.9e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase YpmT PF17431.2 EGG04529.1 - 1.8 8.6 6.3 0.12 12.4 0.7 2.0 2 0 0 2 2 2 0 Uncharacterized YmpT-like Asp_protease PF09668.10 EGG04533.1 - 1.3e-11 44.4 0.2 1.8e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 EGG04533.1 - 3e-07 30.1 0.0 6.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGG04533.1 - 0.00042 20.1 0.0 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.11 EGG04533.1 - 0.0012 18.5 0.6 0.0029 17.3 0.6 1.6 1 0 0 1 1 1 1 XPC-binding domain GET2 PF08690.10 EGG04533.1 - 0.0034 17.1 2.0 0.0042 16.8 2.0 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 HTH_Crp_2 PF13545.6 EGG04533.1 - 0.065 13.2 0.2 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain PAPS_reduct PF01507.19 EGG04534.1 - 2e-25 89.8 0.0 2.8e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family PUL PF08324.11 EGG04534.1 - 0.039 13.2 0.2 0.048 12.9 0.2 1.2 1 0 0 1 1 1 0 PUL domain Peptidase_S8 PF00082.22 EGG04536.1 - 6.2e-44 150.4 0.0 1.3e-43 149.4 0.0 1.5 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EGG04536.1 - 1.9e-10 41.5 0.0 5.3e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Fn3-like domain CTNNBL PF08216.11 EGG04537.1 - 2.1e-32 111.4 0.3 7.4e-32 109.6 0.0 2.1 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 EGG04537.1 - 0.018 15.1 0.0 3.5 7.8 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat PP_kinase PF02503.17 EGG04537.1 - 0.025 14.2 0.0 0.055 13.1 0.0 1.7 1 1 0 1 1 1 0 Polyphosphate kinase middle domain DUF1749 PF08538.10 EGG04538.1 - 9e-75 251.5 0.0 1.1e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 EGG04538.1 - 0.0023 18.5 0.0 0.0036 17.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PuR_N PF09182.10 EGG04538.1 - 0.029 14.3 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal LIDHydrolase PF10230.9 EGG04538.1 - 0.067 12.7 0.0 0.18 11.3 0.0 1.7 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 EGG04538.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Dioxygenase_N PF04444.14 EGG04538.1 - 0.13 12.2 0.0 0.65 9.9 0.0 2.2 3 0 0 3 3 3 0 Catechol dioxygenase N terminus Hydrolase_4 PF12146.8 EGG04538.1 - 0.19 11.0 0.0 0.26 10.5 0.0 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 OPT PF03169.15 EGG04544.1 - 6.7e-116 388.4 31.3 7.6e-116 388.2 31.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4113 PF13438.6 EGG04545.1 - 0.19 11.8 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) DUF2300 PF10062.9 EGG04546.1 - 0.12 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) UTP15_C PF09384.10 EGG04547.1 - 1e-46 158.3 0.0 1.6e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EGG04547.1 - 8.5e-16 58.1 8.4 6.2e-05 23.7 0.1 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG04547.1 - 5.9e-07 29.7 0.1 0.16 12.2 0.0 4.7 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EGG04547.1 - 2.9e-06 25.9 0.0 0.0027 16.1 0.0 2.1 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 EGG04547.1 - 0.0012 18.2 0.0 0.24 10.7 0.0 2.8 3 0 0 3 3 3 2 WD40-like domain BBS2_Mid PF14783.6 EGG04547.1 - 0.032 14.3 0.0 36 4.5 0.0 3.5 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region THF_DHG_CYH_C PF02882.19 EGG04548.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4218 PF13960.6 EGG04549.1 - 0.1 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) DUF4211 PF13926.6 EGG04551.1 - 2.7e-19 69.7 0.0 7.2e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) WD40_like PF17005.5 EGG04552.1 - 0.00015 21.2 0.1 0.0035 16.7 0.1 2.4 2 1 1 3 3 3 1 WD40-like domain ANAPC4_WD40 PF12894.7 EGG04552.1 - 0.0022 18.3 0.0 0.013 15.7 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG04552.1 - 0.014 16.2 0.0 0.21 12.5 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 EGG04552.1 - 0.063 12.5 0.0 0.12 11.6 0.0 1.4 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus D123 PF07065.14 EGG04552.1 - 2 7.5 4.5 1.9 7.6 2.1 1.9 2 0 0 2 2 2 0 D123 Glyco_hydro_32N PF00251.20 EGG04554.1 - 1.7e-29 103.4 4.3 4.1e-21 75.9 4.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EGG04554.1 - 1.3e-22 80.5 0.2 2.9e-22 79.4 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 EGG04554.1 - 0.0049 17.0 0.2 0.0095 16.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) TaqI_C PF12950.7 EGG04554.1 - 0.15 12.2 0.3 7.5 6.7 0.1 2.5 2 0 0 2 2 2 0 TaqI-like C-terminal specificity domain MgsA_C PF12002.8 EGG04555.1 - 1.8e-56 190.7 0.1 2.8e-56 190.0 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EGG04555.1 - 4.7e-21 74.9 0.3 9e-21 74.0 0.3 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EGG04555.1 - 2.1e-12 47.6 0.0 2.4e-11 44.2 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGG04555.1 - 1.4e-05 25.4 2.8 0.011 16.0 1.1 3.6 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.6 EGG04555.1 - 0.00013 22.4 5.2 0.019 15.3 0.1 3.2 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EGG04555.1 - 0.00029 20.8 0.0 0.00064 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGG04555.1 - 0.00052 19.8 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EGG04555.1 - 0.0014 18.3 0.2 0.004 16.7 0.2 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGG04555.1 - 0.0015 19.0 0.0 0.01 16.3 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 EGG04555.1 - 0.0019 17.7 0.0 0.0046 16.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 EGG04555.1 - 0.003 17.3 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG04555.1 - 0.0049 17.4 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGG04555.1 - 0.0065 15.9 1.1 0.044 13.2 0.0 2.6 1 1 2 3 3 3 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EGG04555.1 - 0.0073 15.8 0.2 4.2 6.8 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_23 PF13476.6 EGG04555.1 - 0.013 16.0 0.1 0.037 14.5 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 EGG04555.1 - 0.014 15.7 0.3 1.7 9.0 0.3 2.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGG04555.1 - 0.017 15.1 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGG04555.1 - 0.021 14.6 0.0 0.071 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGG04555.1 - 0.022 14.4 0.1 5 6.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.13 EGG04555.1 - 0.035 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 EGG04555.1 - 0.06 13.6 0.1 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EGG04555.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase CPT PF07931.12 EGG04555.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 EGG04555.1 - 0.077 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGG04555.1 - 0.11 12.9 0.0 0.85 10.0 0.0 2.3 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 EGG04555.1 - 0.11 12.9 0.0 0.5 10.8 0.0 2.2 2 1 0 2 2 2 0 RNA helicase TsaE PF02367.17 EGG04555.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EGG04555.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Haspin_kinase PF12330.8 EGG04556.1 - 5.5e-35 121.0 0.0 9.6e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Mso1_C PF14477.6 EGG04556.1 - 1.8 9.0 14.7 0.13 12.6 0.5 4.4 4 0 0 4 4 4 0 Membrane-polarising domain of Mso1 Nucleo_P87 PF07267.11 EGG04559.1 - 0.037 12.9 0.5 0.041 12.7 0.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4346 PF14251.6 EGG04559.1 - 0.11 12.6 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) Goodbye PF17109.5 EGG04559.1 - 0.28 11.6 0.9 0.39 11.2 0.9 1.1 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain PLA2_B PF01735.18 EGG04560.1 - 5.5e-87 292.2 0.1 8.4e-87 291.6 0.1 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 EGG04560.1 - 7.7e-06 26.2 0.1 2.2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase FAR1 PF03101.15 EGG04561.1 - 2.2e-06 28.2 0.8 2.2e-06 28.2 0.8 2.1 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.11 EGG04561.1 - 0.00068 20.0 4.3 0.00068 20.0 0.2 2.5 2 0 0 2 2 2 1 Transcription factor AFT Fumerase_C PF05683.12 EGG04561.1 - 0.17 11.2 0.0 0.4 10.0 0.0 1.5 1 0 0 1 1 1 0 Fumarase C-terminus TFIID-18kDa PF02269.16 EGG04562.1 - 7e-12 45.2 0.1 2.1e-11 43.7 0.1 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Pneumo_ncap PF03246.13 EGG04562.1 - 0.12 11.1 0.3 0.17 10.6 0.3 1.1 1 0 0 1 1 1 0 Pneumovirus nucleocapsid protein adh_short PF00106.25 EGG04564.1 - 8.3e-41 139.6 1.7 2.2e-40 138.2 1.7 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG04564.1 - 4.9e-40 137.5 0.4 9.6e-40 136.6 0.4 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG04564.1 - 3.3e-09 36.9 0.2 5.2e-09 36.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGG04564.1 - 0.011 14.9 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Transglut_core3 PF13471.6 EGG04564.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily MR_MLE_C PF13378.6 EGG04564.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Enolase C-terminal domain-like MKT1_C PF12246.8 EGG04565.1 - 8.4e-78 260.9 0.1 1.3e-77 260.3 0.1 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EGG04565.1 - 2.8e-26 91.7 0.1 1.5e-25 89.3 0.0 2.3 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 EGG04565.1 - 5.6e-08 33.2 0.0 1.4e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain Hydrolase_4 PF12146.8 EGG04566.1 - 6.9e-09 35.3 0.1 3.5e-07 29.7 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EGG04566.1 - 1.6e-06 28.1 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG04566.1 - 2e-06 28.5 0.0 3.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG04566.1 - 4.7e-06 26.4 0.0 1.3e-05 25.0 0.0 1.6 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG04566.1 - 5e-05 22.9 0.4 0.012 15.1 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 EGG04566.1 - 0.0012 18.8 0.0 0.0029 17.6 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 EGG04566.1 - 0.009 15.6 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 EGG04566.1 - 0.051 13.7 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain MRP-S32 PF10210.9 EGG04566.1 - 0.14 12.7 0.5 20 5.8 0.0 2.7 2 2 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 Plasmid_RAQPRD PF09686.10 EGG04568.1 - 0.16 12.2 3.8 0.49 10.6 3.8 1.8 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Sds3 PF08598.11 EGG04569.1 - 4.7e-12 46.4 11.2 5.8e-12 46.1 9.6 1.8 1 1 0 1 1 1 1 Sds3-like UPF0175 PF03683.13 EGG04569.1 - 0.0046 16.6 2.4 0.0053 16.4 0.1 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0175) Bombinin PF05298.11 EGG04569.1 - 0.034 13.8 3.5 0.051 13.3 3.2 1.4 1 1 0 1 1 1 0 Bombinin AAA_23 PF13476.6 EGG04569.1 - 0.38 11.2 8.0 0.46 10.9 8.0 1.1 1 0 0 1 1 1 0 AAA domain Mt_ATP-synt_B PF05405.14 EGG04569.1 - 0.48 10.0 6.9 0.24 11.0 3.1 2.0 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Alpha_kinase PF02816.18 EGG04571.1 - 3e-10 40.5 0.0 4.9e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family IDO PF01231.18 EGG04571.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase HA2 PF04408.23 EGG04572.1 - 2.6e-16 59.8 1.3 4.2e-16 59.2 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGG04572.1 - 5.9e-16 58.8 0.3 4.8e-15 55.9 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG04572.1 - 8.5e-10 38.7 0.1 1.6e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGG04572.1 - 4.1e-05 23.9 0.2 0.00016 21.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.16 EGG04572.1 - 0.00018 21.8 0.0 0.00048 20.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 EGG04572.1 - 0.00079 19.8 0.2 0.0064 16.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGG04572.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGG04572.1 - 0.054 12.6 0.0 0.15 11.1 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.14 EGG04572.1 - 0.083 12.9 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Tyrosinase PF00264.20 EGG04573.1 - 9.9e-15 55.4 1.6 1.3e-14 55.1 1.6 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase E1-E2_ATPase PF00122.20 EGG04578.1 - 3e-47 160.5 0.1 3e-47 160.5 0.1 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGG04578.1 - 1.4e-19 71.2 2.9 4e-19 69.8 2.9 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGG04578.1 - 4.2e-13 48.8 0.0 1.4e-12 47.1 0.1 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG04578.1 - 0.0002 21.2 0.1 0.0033 17.2 0.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG04578.1 - 0.082 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Methyltr_RsmB-F PF01189.17 EGG04582.1 - 7.6e-23 81.2 0.0 1.2e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 EGG04582.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EGG04582.1 - 0.071 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EGG04582.1 - 0.093 12.8 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase RRM_1 PF00076.22 EGG04583.1 - 3.3e-13 49.2 0.0 6e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 EGG04584.1 - 2.4e-37 128.7 0.1 2.7e-37 128.5 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L30 PF00327.20 EGG04585.1 - 4.9e-11 42.3 0.0 8.4e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e TLV_coat PF00429.19 EGG04585.1 - 0.079 11.6 0.5 0.088 11.5 0.5 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) G_glu_transpept PF01019.21 EGG04586.1 - 1.2e-137 459.9 0.0 1.3e-137 459.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MT-A70 PF05063.14 EGG04589.1 - 1.6e-12 47.7 0.2 1.2e-10 41.6 0.2 2.4 1 1 0 1 1 1 1 MT-A70 Ysc84 PF04366.12 EGG04592.1 - 1.1e-41 141.6 0.0 2e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Ribosomal_S6e PF01092.19 EGG04593.1 - 1.5e-56 189.7 0.6 2.3e-56 189.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e Atg14 PF10186.9 EGG04593.1 - 0.5 9.4 4.5 0.68 9.0 4.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4175 PF13779.6 EGG04595.1 - 4.1 5.2 8.4 5.1 4.9 8.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mito_fiss_reg PF05308.11 EGG04595.1 - 4.1 7.4 9.0 0.1 12.6 0.9 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.19 EGG04595.1 - 5.6 6.4 11.7 1.2 8.6 1.9 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Barttin PF15462.6 EGG04596.1 - 0.0064 16.3 1.7 0.0071 16.1 1.7 1.2 1 0 0 1 1 1 1 Bartter syndrome, infantile, with sensorineural deafness (Barttin) ELFV_dehydrog PF00208.21 EGG04598.1 - 4e-56 190.4 0.0 7.1e-56 189.6 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EGG04598.1 - 2.4e-21 75.1 0.0 7.6e-14 50.3 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase Spore_III_AB PF09548.10 EGG04598.1 - 0.071 13.2 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DEAD PF00270.29 EGG04599.1 - 2.6e-47 160.8 0.0 4.6e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG04599.1 - 2.4e-30 105.1 0.0 4.9e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG04599.1 - 0.0073 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGG04599.1 - 0.057 12.6 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EGG04599.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Forkhead PF00250.18 EGG04602.1 - 2.4e-33 114.2 0.0 5.3e-33 113.1 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain KRTAP PF11759.8 EGG04602.1 - 0.019 15.5 10.1 0.019 15.5 10.1 2.0 2 0 0 2 2 2 0 Keratin-associated matrix SirA PF10747.9 EGG04602.1 - 1.7 9.0 5.3 2.2 8.6 1.7 2.3 2 0 0 2 2 2 0 Sporulation inhibitor of replication protein SirA MOZ_SAS PF01853.18 EGG04604.1 - 1.1e-45 155.5 1.0 1.2e-45 155.3 1.0 1.0 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.7 EGG04604.1 - 0.0001 22.6 0.0 0.00015 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG04604.1 - 0.00068 19.9 0.0 0.00081 19.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Rap1_C PF11626.8 EGG04605.1 - 0.00011 22.3 0.1 0.00019 21.4 0.1 1.5 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Peptidase_C97 PF05903.14 EGG04606.1 - 7.9e-37 126.4 0.0 9e-37 126.2 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 EGG04607.1 - 4.5e-10 39.2 0.1 5e-10 39.1 0.1 1.0 1 0 0 1 1 1 1 PUL domain Exonuc_V_gamma PF04257.14 EGG04607.1 - 0.061 11.5 0.2 0.083 11.1 0.2 1.2 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit UPF0242 PF06785.11 EGG04608.1 - 0.0063 16.6 3.8 0.011 15.9 3.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus KxDL PF10241.9 EGG04608.1 - 0.026 14.8 1.4 0.71 10.2 1.4 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein Fez1 PF06818.15 EGG04608.1 - 0.076 13.5 7.2 0.042 14.3 3.7 2.2 2 0 0 2 2 2 0 Fez1 Spc7 PF08317.11 EGG04608.1 - 0.11 11.4 3.9 0.21 10.4 3.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 EGG04608.1 - 0.13 12.5 3.1 0.27 11.4 3.1 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Snapin_Pallidin PF14712.6 EGG04608.1 - 0.3 11.5 3.6 5.8 7.4 3.9 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Seryl_tRNA_N PF02403.22 EGG04608.1 - 2.4 8.4 6.9 7.8 6.8 6.9 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Syntaxin_2 PF14523.6 EGG04608.1 - 3.5 8.0 10.2 6.6 7.2 2.2 2.6 1 1 1 2 2 2 0 Syntaxin-like protein ATP-synt_ab PF00006.25 EGG04610.1 - 8e-68 228.3 0.0 1.3e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGG04610.1 - 4.9e-11 43.0 0.4 8.8e-11 42.2 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 EGG04610.1 - 0.09 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Abhydrolase_1 PF00561.20 EGG04611.1 - 8.1e-17 61.7 0.0 6.1e-16 58.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG04611.1 - 8.2e-15 54.7 0.0 2.9e-14 52.9 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG04611.1 - 5.6e-09 36.9 0.0 7.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.11 EGG04611.1 - 5e-05 22.3 0.0 7.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_4 PF08386.10 EGG04611.1 - 0.00068 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein UPF0227 PF05728.12 EGG04611.1 - 0.0027 17.7 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 EGG04611.1 - 0.0092 16.1 0.0 0.026 14.6 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain DLH PF01738.18 EGG04611.1 - 0.013 15.1 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family PGAP1 PF07819.13 EGG04611.1 - 0.032 14.0 0.1 0.059 13.1 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Bse634I PF07832.11 EGG04611.1 - 0.053 12.9 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Cfr10I/Bse634I restriction endonuclease FSH1 PF03959.13 EGG04611.1 - 0.083 12.5 0.0 0.35 10.5 0.0 2.1 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Lipase_2 PF01674.18 EGG04611.1 - 0.098 12.2 0.1 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 2) Fe_dep_repr_C PF02742.15 EGG04611.1 - 0.12 12.4 0.9 0.28 11.3 0.0 2.0 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain PNP_phzG_C PF10590.9 EGG04613.1 - 3.1e-20 72.0 0.3 6e-20 71.0 0.3 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EGG04613.1 - 4.2e-19 68.5 0.0 6.6e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EGG04613.1 - 0.0014 19.2 0.0 0.0029 18.2 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EGG04613.1 - 0.092 12.3 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like DHODB_Fe-S_bind PF10418.9 EGG04616.1 - 0.026 14.3 0.4 0.057 13.2 0.4 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B HTH_23 PF13384.6 EGG04620.1 - 0.017 14.9 0.1 0.048 13.5 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_33 PF13592.6 EGG04620.1 - 0.093 12.4 0.3 0.25 11.0 0.1 1.8 2 0 0 2 2 2 0 Winged helix-turn helix Isy1 PF06246.12 EGG04622.1 - 1.5e-89 300.0 0.5 1.7e-89 299.8 0.5 1.1 1 0 0 1 1 1 1 Isy1-like splicing family SRP19 PF01922.17 EGG04624.1 - 1.8e-23 83.3 0.0 3.1e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Cation_ATPase PF13246.6 EGG04625.1 - 1.3e-11 44.4 0.0 4.2e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) DEAD PF00270.29 EGG04629.1 - 1.3e-33 116.3 1.9 2.8e-32 111.9 1.9 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG04629.1 - 4.3e-26 91.4 0.1 2.3e-25 89.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG04629.1 - 0.00021 21.4 0.3 0.00053 20.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EGG04629.1 - 0.0021 18.3 0.0 0.0088 16.2 0.0 2.0 1 0 0 1 1 1 1 Helicase C-terminal domain DUF445 PF04286.12 EGG04629.1 - 0.037 13.8 0.4 0.06 13.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HeLo PF14479.6 EGG04629.1 - 0.49 10.2 4.1 0.13 12.1 0.6 1.8 2 0 0 2 2 2 0 Prion-inhibition and propagation CNOT11 PF10155.9 EGG04629.1 - 1.2 9.3 4.7 16 5.7 4.2 2.5 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 11 ThiF PF00899.21 EGG04630.1 - 3e-26 92.3 0.1 4.2e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 ThiF family Peptidase_M28 PF04389.17 EGG04634.1 - 5.5e-19 68.6 0.0 9.2e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 EGG04634.1 - 1.5e-15 57.4 0.0 3.7e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 EGG04634.1 - 7.4e-11 41.9 0.0 1.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 EGG04634.1 - 0.019 14.4 0.4 0.034 13.6 0.0 1.5 2 0 0 2 2 2 0 Nicastrin Fis1_TPR_C PF14853.6 EGG04635.1 - 3.2e-24 84.8 0.2 5.2e-24 84.1 0.2 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EGG04635.1 - 4.1e-14 52.0 0.0 6.9e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EGG04635.1 - 4.8e-05 23.2 0.3 9.6e-05 22.2 0.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG04635.1 - 0.077 13.5 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG04635.1 - 0.12 13.2 0.0 1.4 10.0 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG04635.1 - 0.13 13.0 0.0 0.66 10.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 EGG04635.1 - 0.16 12.3 0.5 18 5.9 0.0 2.8 3 0 0 3 3 3 0 PPR repeat CRISPR_Cas9_WED PF18061.1 EGG04637.1 - 0.012 15.8 0.7 0.015 15.3 0.7 1.2 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain DUF4556 PF15094.6 EGG04638.1 - 0.034 13.4 0.1 0.14 11.4 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4556) Pkinase PF00069.25 EGG04639.1 - 7.6e-63 212.3 2.3 7.6e-44 150.1 0.1 2.4 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG04639.1 - 2.1e-28 99.3 0.1 3.2e-21 75.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG04639.1 - 1.2e-08 34.3 0.1 1.7e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGG04639.1 - 1.2e-05 25.3 0.5 0.01 15.7 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGG04639.1 - 0.00029 20.3 0.8 0.0079 15.6 0.0 2.8 2 1 1 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGG04639.1 - 0.0062 15.9 0.3 0.021 14.2 0.0 2.0 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EGG04639.1 - 0.016 14.0 2.1 0.035 12.9 2.1 1.7 1 1 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EGG04639.1 - 0.019 14.0 0.4 0.035 13.2 0.1 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_C PF00433.24 EGG04639.1 - 0.02 15.6 1.4 0.046 14.4 1.4 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.11 EGG04639.1 - 0.094 11.7 0.9 0.16 10.9 0.1 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EGG04639.1 - 0.17 11.4 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family EBP50_C PF09007.11 EGG04640.1 - 2.1 9.3 8.5 0.82 10.7 3.7 2.2 2 1 0 2 2 2 0 EBP50, C-terminal TBPIP PF07106.13 EGG04641.1 - 0.35 10.8 1.4 0.38 10.7 0.1 1.8 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain CxC1 PF18802.1 EGG04643.1 - 1.7e-28 98.8 0.0 2.9e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG04643.1 - 3.9e-05 23.8 0.0 7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases MPC PF03650.13 EGG04645.1 - 8e-41 138.6 0.4 9e-41 138.5 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Suv3_C_1 PF18147.1 EGG04645.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 DUF2799 PF10973.8 EGG04647.1 - 0.076 13.5 0.3 0.64 10.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2799) cobW PF02492.19 EGG04648.1 - 2.2e-33 115.3 0.0 2.8e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EGG04648.1 - 4e-07 29.3 0.0 9e-05 21.6 0.0 2.0 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 EGG04648.1 - 0.0044 16.8 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EGG04648.1 - 0.029 14.9 0.2 0.073 13.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGG04648.1 - 0.045 13.3 0.0 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 EGG04648.1 - 0.051 13.1 0.2 6.1 6.3 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Pox_A32 PF04665.12 EGG04648.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Pkinase PF00069.25 EGG04651.1 - 5.4e-65 219.4 0.0 7.1e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG04651.1 - 2.1e-25 89.5 0.0 3.4e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG04651.1 - 8.1e-05 22.1 0.1 0.055 12.8 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 EGG04651.1 - 0.00014 20.9 0.3 0.00025 20.1 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGG04651.1 - 0.00097 18.8 0.1 0.0016 18.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family AFT PF08731.11 EGG04655.1 - 0.0029 18.0 0.3 0.0076 16.6 0.3 1.7 1 0 0 1 1 1 1 Transcription factor AFT tRNA-synt_2d PF01409.20 EGG04656.1 - 0.069 12.6 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) T4_Rnl2_C PF18043.1 EGG04656.1 - 0.3 11.3 2.4 0.48 10.6 0.3 2.0 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal DUF4218 PF13960.6 EGG04657.1 - 0.0047 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Allexi_40kDa PF05549.11 EGG04659.1 - 7.5 6.0 7.7 0.3 10.5 0.9 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein Viral_P18 PF04521.13 EGG04662.1 - 0.18 11.6 4.2 0.075 12.8 0.5 2.2 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein EOS1 PF12326.8 EGG04662.1 - 1.1 9.2 2.9 2 8.3 2.9 1.5 1 0 0 1 1 1 0 N-glycosylation protein Zip PF02535.22 EGG04662.1 - 2.7 7.1 4.7 3.9 6.6 4.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 EGG04662.1 - 4.9 6.9 15.0 1.2 8.9 12.0 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PCI PF01399.27 EGG04663.1 - 0.081 13.4 0.0 0.35 11.4 0.0 2.1 1 1 0 1 1 1 0 PCI domain TPR_2 PF07719.17 EGG04663.1 - 0.091 12.9 0.2 0.28 11.4 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat SAP PF02037.27 EGG04664.1 - 3.1e-13 49.1 0.1 8.4e-12 44.6 0.2 2.4 2 0 0 2 2 2 1 SAP domain RRM_1 PF00076.22 EGG04664.1 - 0.00011 21.9 0.0 0.00028 20.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSB_motif PF16294.5 EGG04664.1 - 0.0012 19.1 0.0 0.0044 17.3 0.0 2.0 1 0 0 1 1 1 1 RNSP1-SAP18 binding (RSB) motif HeH PF12949.7 EGG04664.1 - 0.14 11.9 0.1 3.4 7.5 0.2 2.4 2 0 0 2 2 2 0 HeH/LEM domain SlyX PF04102.12 EGG04666.1 - 0.11 13.2 0.1 0.29 11.8 0.1 1.7 1 0 0 1 1 1 0 SlyX Alpha_kinase PF02816.18 EGG04667.1 - 1.8e-09 38.0 0.6 2.6e-09 37.5 0.6 1.2 1 0 0 1 1 1 1 Alpha-kinase family BetaGal_dom3 PF13363.6 EGG04669.1 - 0.12 11.9 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 TT_ORF2 PF02957.15 EGG04669.1 - 1.8 9.5 5.4 1.1 10.2 3.5 1.6 1 1 1 2 2 2 0 TT viral ORF2 Glyco_hydro_12 PF01670.16 EGG04673.1 - 2.2e-15 57.2 0.6 3.3e-15 56.7 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 dCMP_cyt_deam_1 PF00383.23 EGG04675.1 - 1e-10 41.4 0.7 1.2e-10 41.1 0.7 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EGG04675.1 - 3.3e-07 30.6 0.2 0.00053 20.2 0.0 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EGG04675.1 - 0.03 13.9 4.0 0.55 9.8 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Laminin_II PF06009.12 EGG04676.1 - 0.00096 19.2 1.2 0.0023 17.9 1.2 1.6 1 0 0 1 1 1 1 Laminin Domain II DUF4140 PF13600.6 EGG04676.1 - 0.089 13.2 0.0 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CxC1 PF18802.1 EGG04682.1 - 1.6e-18 66.8 0.1 4e-16 59.0 0.1 2.4 1 1 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Cofac_haem_bdg PF04187.13 EGG04682.1 - 0.018 15.0 0.0 0.084 12.8 0.0 1.9 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN KDZ PF18758.1 EGG04682.1 - 0.17 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase HECT PF00632.25 EGG04684.1 - 1.3e-93 313.9 0.0 1.6e-93 313.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) peroxidase PF00141.23 EGG04685.1 - 2.9e-46 158.0 0.0 3.9e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DBR1 PF05011.13 EGG04686.1 - 4e-39 134.2 0.1 6.6e-39 133.5 0.1 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EGG04686.1 - 1.1e-08 35.9 0.1 2.1e-08 34.9 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.27 EGG04689.1 - 3.6e-44 150.6 0.0 3.6e-26 92.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGG04689.1 - 8e-31 107.7 28.1 1.2e-16 61.2 5.0 4.6 5 0 0 5 5 5 3 ABC transporter transmembrane region SMC_N PF02463.19 EGG04689.1 - 9.3e-14 51.4 0.0 2.2e-06 27.2 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGG04689.1 - 7.6e-05 23.0 0.8 0.5 10.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EGG04689.1 - 0.00012 22.0 1.9 2.4 7.9 0.0 3.7 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGG04689.1 - 0.00075 19.9 0.2 0.41 11.0 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EGG04689.1 - 0.0022 17.6 0.2 0.91 9.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGG04689.1 - 0.0074 16.4 0.0 7.6 6.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 EGG04689.1 - 0.0075 15.2 1.7 1.3 7.8 0.0 3.1 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 EGG04689.1 - 0.009 15.7 3.8 0.87 9.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 EGG04689.1 - 0.01 14.9 0.5 0.36 9.8 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 EGG04689.1 - 0.026 14.4 0.5 15 5.5 0.0 4.0 4 0 0 4 4 4 0 NACHT domain ATPase PF06745.13 EGG04689.1 - 0.055 12.8 0.9 11 5.2 0.1 2.6 2 0 0 2 2 2 0 KaiC AAA_15 PF13175.6 EGG04689.1 - 0.09 12.5 0.2 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 EGG04689.1 - 0.11 12.2 0.3 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGG04689.1 - 0.14 12.3 2.0 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 EGG04689.1 - 0.15 12.5 2.4 4 7.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 EGG04689.1 - 0.18 11.2 0.4 5.7 6.3 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein DEAD PF00270.29 EGG04689.1 - 0.18 11.5 0.6 24 4.6 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase cobW PF02492.19 EGG04689.1 - 0.19 11.3 1.7 1.7 8.2 0.6 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 EGG04689.1 - 0.68 9.6 2.5 13 5.5 0.0 3.3 4 0 0 4 4 3 0 IstB-like ATP binding protein Pet127 PF08634.10 EGG04691.1 - 9.2e-79 264.7 2.9 7.2e-64 215.9 0.5 2.3 1 1 1 2 2 2 2 Mitochondrial protein Pet127 DUF3045 PF11243.8 EGG04691.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) STIL_N PF15253.6 EGG04691.1 - 0.39 9.6 4.2 0.72 8.7 4.2 1.3 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus Ribosomal_S13_N PF08069.12 EGG04695.1 - 9.4e-31 105.6 0.1 1.8e-30 104.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EGG04695.1 - 9.6e-15 54.6 0.5 1.4e-14 54.0 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 YflT PF11181.8 EGG04695.1 - 0.015 15.8 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Heat induced stress protein YflT PAX PF00292.18 EGG04695.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain CutC PF03932.14 EGG04696.1 - 7.2e-43 146.4 0.8 5.3e-22 78.3 0.1 2.2 1 1 1 2 2 2 2 CutC family GA PF01468.17 EGG04696.1 - 0.25 11.6 1.4 0.7 10.2 1.4 1.7 1 0 0 1 1 1 0 GA module His_Phos_2 PF00328.22 EGG04697.1 - 5.1e-76 256.5 0.0 6.4e-76 256.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EGG04697.1 - 4.3e-38 129.3 0.1 1.2e-37 127.9 0.1 1.9 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EGG04697.1 - 9.2e-09 35.2 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF4030 PF13222.6 EGG04697.1 - 0.06 13.5 0.1 0.24 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4030) NAT PF04768.13 EGG04698.1 - 3.8e-31 108.0 0.1 6.2e-20 71.5 0.0 2.2 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase Mit_KHE1 PF10173.9 EGG04699.1 - 5.7e-55 186.4 4.4 5.7e-55 186.4 4.4 2.0 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related HSA PF07529.13 EGG04699.1 - 3.6 8.0 9.3 3.1 8.2 7.5 1.8 2 0 0 2 2 2 0 HSA YAF2_RYBP PF17219.3 EGG04700.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif I-EGF_1 PF18372.1 EGG04700.1 - 0.3 11.2 6.4 3.6 7.8 2.0 2.9 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 Ldh_1_C PF02866.18 EGG04701.1 - 2.1e-45 154.6 0.0 3.7e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGG04701.1 - 1.3e-44 151.7 0.1 1.8e-44 151.2 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EGG04701.1 - 2.3e-05 23.6 0.0 3.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 EGG04701.1 - 0.026 14.1 0.1 0.43 10.1 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase SNF2_N PF00176.23 EGG04703.1 - 1.3e-44 152.3 1.0 1.5e-44 152.2 1.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGG04703.1 - 1.5e-07 31.6 0.0 1.9e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG04703.1 - 1.7e-07 31.2 0.0 2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGG04703.1 - 0.00059 19.6 0.0 0.00075 19.2 0.0 1.3 1 1 0 1 1 1 1 SWI2/SNF2 ATPase Helicase_C PF00271.31 EGG04704.1 - 4.4e-15 56.0 0.0 7.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PPDK_N PF01326.19 EGG04704.1 - 0.091 12.0 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Spore_III_AB PF09548.10 EGG04705.1 - 0.023 14.8 0.6 0.12 12.5 1.0 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) BAR_3 PF16746.5 EGG04705.1 - 0.26 11.0 8.0 0.51 10.0 8.0 1.4 1 0 0 1 1 1 0 BAR domain of APPL family TBCA PF02970.16 EGG04705.1 - 0.97 9.8 5.1 12 6.3 0.3 2.7 2 0 0 2 2 2 0 Tubulin binding cofactor A Apt1 PF10351.9 EGG04706.1 - 1.8e-101 340.4 0.0 1.8e-101 340.4 0.0 2.9 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EGG04706.1 - 9e-44 150.1 0.8 4.1e-30 105.1 0.1 2.7 2 0 0 2 2 2 2 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EGG04706.1 - 5.6e-42 143.5 0.0 1.1e-41 142.5 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EGG04706.1 - 5.2e-39 133.6 0.1 1.3e-38 132.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EGG04706.1 - 9.7e-23 80.8 0.0 1.2e-21 77.4 0.0 2.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Ribonuc_red_sm PF00268.21 EGG04707.1 - 3.8e-121 403.8 0.2 4.7e-121 403.5 0.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain MFMR PF07777.11 EGG04708.1 - 0.14 12.6 3.4 0.12 12.8 0.9 1.9 1 1 1 2 2 2 0 G-box binding protein MFMR TMEM171 PF15471.6 EGG04708.1 - 1.8 7.5 3.3 2 7.4 3.3 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 ECH_1 PF00378.20 EGG04709.1 - 2.2e-26 92.7 0.0 6.4e-26 91.2 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGG04709.1 - 7.5e-06 25.7 0.0 9.8e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase hDGE_amylase PF14701.6 EGG04710.1 - 2.4e-172 574.0 0.0 3.7e-172 573.4 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EGG04710.1 - 2.3e-115 385.6 0.0 3.2e-115 385.1 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EGG04710.1 - 8.2e-80 268.1 0.0 1.4e-79 267.4 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EGG04710.1 - 6.8e-24 83.8 0.0 1.5e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Neprosin PF03080.15 EGG04711.1 - 0.094 12.1 0.4 0.43 9.9 0.1 1.8 1 1 0 2 2 2 0 Neprosin DGF-1_C PF11040.8 EGG04712.1 - 0.31 11.1 1.4 4.1 7.5 0.1 2.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Alpha_kinase PF02816.18 EGG04713.1 - 1.4e-12 48.1 0.7 2.6e-12 47.3 0.7 1.4 1 0 0 1 1 1 1 Alpha-kinase family Retrotran_gag_2 PF14223.6 EGG04716.1 - 0.0015 18.2 1.0 0.0029 17.3 0.3 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF98 PF01947.16 EGG04716.1 - 0.065 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase RRP7 PF12923.7 EGG04716.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Mito_carr PF00153.27 EGG04717.1 - 6.3e-32 109.4 1.6 2.4e-17 62.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TFIIS_C PF01096.18 EGG04718.1 - 4.1e-19 68.1 12.8 7.9e-19 67.2 4.5 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGG04718.1 - 4.5e-10 39.2 1.9 4.5e-10 39.2 1.9 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EGG04718.1 - 3.4e-06 26.9 6.7 0.00054 19.9 0.8 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain DUF3797 PF12677.7 EGG04718.1 - 0.0011 18.8 1.9 1.3 9.0 1.4 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3797) DUF2752 PF10825.8 EGG04718.1 - 0.021 14.9 0.0 7.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) zinc-ribbons_6 PF07191.12 EGG04718.1 - 0.03 14.3 0.8 0.03 14.3 0.8 2.4 2 1 0 2 2 2 0 zinc-ribbons Lar_restr_allev PF14354.6 EGG04718.1 - 0.031 14.7 4.4 0.34 11.3 0.3 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Auto_anti-p27 PF06677.12 EGG04718.1 - 0.072 13.3 4.2 0.39 10.9 1.3 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 EGG04718.1 - 0.23 11.4 3.3 0.3 11.1 0.6 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain FlhC PF05280.11 EGG04718.1 - 0.28 10.9 3.9 1.3 8.8 1.2 2.2 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhC) zf-ribbon_3 PF13248.6 EGG04718.1 - 0.4 10.1 7.4 0.59 9.6 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain PADR1 PF08063.12 EGG04718.1 - 0.99 9.2 10.4 6.4 6.6 1.2 2.7 2 2 0 2 2 2 0 PADR1 (NUC008) domain IBR PF01485.21 EGG04718.1 - 1.9 8.7 9.6 0.47 10.7 0.4 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-ACC PF17848.1 EGG04718.1 - 2.5 8.3 0.1 2.5 8.3 0.1 3.6 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zf-TFIIB PF13453.6 EGG04718.1 - 2.8 7.4 11.2 0.35 10.2 1.4 2.5 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-C4_Topoisom PF01396.19 EGG04718.1 - 7.6 6.4 10.6 1.3 8.8 1.5 2.7 2 2 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger BRCT PF00533.26 EGG04720.1 - 4.7e-21 74.9 1.5 2.3e-07 31.1 0.0 5.9 5 1 1 6 6 6 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGG04720.1 - 6.6e-13 48.4 1.9 1.8e-05 24.6 0.0 3.9 4 0 0 4 4 4 2 twin BRCT domain BRCT_2 PF16589.5 EGG04720.1 - 8.1e-10 39.0 0.0 0.0016 18.8 0.0 3.9 3 1 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain DUF2441 PF10386.9 EGG04720.1 - 0.024 14.6 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) LIG3_BRCT PF16759.5 EGG04720.1 - 0.033 14.5 1.2 6.4 7.1 0.1 3.2 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain Herpes_LP PF03363.13 EGG04720.1 - 0.28 10.9 4.0 0.5 10.1 0.3 2.6 3 0 0 3 3 3 0 Herpesvirus leader protein RNase_H2-Ydr279 PF09468.10 EGG04724.1 - 0.096 12.9 0.6 0.15 12.2 0.4 1.4 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF1104 PF06518.11 EGG04724.1 - 0.14 12.6 0.6 0.14 12.6 0.6 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) LMBR1 PF04791.16 EGG04724.1 - 4 6.2 5.3 1 8.2 1.9 1.5 1 1 1 2 2 2 0 LMBR1-like membrane protein DUF4574 PF15141.6 EGG04725.1 - 1.1 9.3 4.0 6.1 6.8 0.3 2.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 PPV_E1_N PF00524.18 EGG04726.1 - 6 7.3 10.5 16 5.9 10.5 1.7 1 1 0 1 1 1 0 E1 Protein, N terminal domain Urotensin_II PF02083.15 EGG04727.1 - 0.16 11.7 0.9 0.44 10.3 0.9 1.7 1 0 0 1 1 1 0 Urotensin II PHD PF00628.29 EGG04728.1 - 0.028 14.3 0.7 0.028 14.3 0.7 1.6 1 1 0 1 1 1 0 PHD-finger Nas2_N PF18265.1 EGG04728.1 - 0.16 11.9 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 Nas2 N_terminal domain Anti-TRAP PF15777.5 EGG04728.1 - 0.38 10.7 3.2 0.75 9.8 3.2 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein ABC_tran_CTD PF16326.5 EGG04731.1 - 1.5 9.1 18.5 0.74 10.1 1.2 4.3 5 0 0 5 5 5 0 ABC transporter C-terminal domain XhlA PF10779.9 EGG04731.1 - 6.8 7.0 6.6 7.8 6.8 0.1 3.3 4 0 0 4 4 4 0 Haemolysin XhlA SR-25 PF10500.9 EGG04734.1 - 0.1 12.2 18.3 0.16 11.6 18.1 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein EVI2A PF05399.11 EGG04734.1 - 0.8 9.3 5.6 1.4 8.5 5.6 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Syntaxin PF00804.25 EGG04735.1 - 1.3e-31 109.9 8.0 1.3e-31 109.9 8.0 1.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 EGG04735.1 - 2e-07 30.9 1.0 2e-07 30.9 1.0 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 EGG04735.1 - 6.5e-05 23.2 13.2 0.00024 21.4 5.9 2.4 2 0 0 2 2 2 1 Syntaxin-like protein Baculo_PEP_C PF04513.12 EGG04735.1 - 0.005 16.9 7.6 0.033 14.2 2.1 2.4 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus VitD-bind_III PF09164.10 EGG04735.1 - 0.0068 16.4 0.6 0.026 14.5 0.3 2.1 1 1 1 2 2 1 1 Vitamin D binding protein, domain III Use1 PF09753.9 EGG04735.1 - 0.014 15.1 10.1 0.033 13.9 10.1 1.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 ETRAMP PF09716.10 EGG04735.1 - 0.017 15.2 1.4 0.03 14.4 0.8 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NPV_P10 PF05531.12 EGG04735.1 - 0.021 15.3 4.4 1.9 9.0 0.1 2.8 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF2951 PF11166.8 EGG04735.1 - 0.022 15.0 0.9 0.022 15.0 0.9 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF2951) NAP PF00956.18 EGG04735.1 - 0.035 13.3 7.8 0.76 8.9 7.8 2.2 1 1 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF2207 PF09972.9 EGG04735.1 - 0.043 12.6 2.1 0.054 12.3 0.3 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4366 PF14283.6 EGG04735.1 - 0.057 13.5 2.7 0.063 13.3 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF745 PF05335.13 EGG04735.1 - 0.073 12.8 14.1 0.61 9.8 8.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF745) IL11 PF07400.11 EGG04735.1 - 0.1 12.3 1.3 1.1 8.9 0.2 2.4 2 0 0 2 2 2 0 Interleukin 11 Spectrin PF00435.21 EGG04735.1 - 0.11 13.0 8.8 1.7 9.2 0.3 3.1 3 1 0 3 3 2 0 Spectrin repeat Syntaxin-6_N PF09177.11 EGG04735.1 - 0.12 13.0 10.2 1.4 9.5 3.3 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4231 PF14015.6 EGG04735.1 - 0.2 12.2 1.5 0.32 11.5 0.3 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF4231) Occludin_ELL PF07303.13 EGG04735.1 - 0.27 12.0 8.9 1.8 9.3 0.6 3.4 3 1 0 3 3 3 0 Occludin homology domain DUF5345 PF17280.2 EGG04735.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.1 3 0 0 3 3 1 0 Family of unknown function (DUF5345) Sigma_reg_N PF13800.6 EGG04735.1 - 0.43 10.9 2.7 0.88 9.9 0.5 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Cnd1 PF12717.7 EGG04735.1 - 0.62 10.1 5.9 2.4 8.2 0.6 2.4 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF1664 PF07889.12 EGG04735.1 - 0.63 10.1 12.1 0.57 10.2 1.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Prominin PF05478.11 EGG04735.1 - 0.65 7.9 14.1 0.76 7.6 1.8 2.7 2 1 0 2 2 2 0 Prominin DUF948 PF06103.11 EGG04735.1 - 0.82 10.0 18.5 0.74 10.1 1.9 4.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 EGG04735.1 - 0.96 9.8 9.1 1.6 9.1 0.6 4.0 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LMBR1 PF04791.16 EGG04735.1 - 1.2 8.0 10.4 2.2 7.1 10.4 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein Allexi_40kDa PF05549.11 EGG04735.1 - 1.6 8.2 14.8 0.11 12.0 2.3 2.6 1 1 1 3 3 3 0 Allexivirus 40kDa protein Herpes_US9 PF06072.11 EGG04735.1 - 1.6 8.6 3.3 1.2 9.1 0.3 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 MCU PF04678.13 EGG04735.1 - 2 8.5 11.7 48 4.0 11.7 2.5 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DASH_Dam1 PF08653.10 EGG04735.1 - 2 8.3 4.8 6.9 6.5 0.1 3.1 2 1 1 3 3 3 0 DASH complex subunit Dam1 Fib_alpha PF08702.10 EGG04735.1 - 3.1 8.0 14.9 13 6.0 0.5 3.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 EGG04735.1 - 3.4 7.7 15.2 1 9.4 3.5 3.3 2 1 1 3 3 3 0 Laminin Domain II Med9 PF07544.13 EGG04735.1 - 3.7 7.7 6.9 32 4.7 0.5 4.0 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Vac_Fusion PF02346.16 EGG04735.1 - 4.2 7.1 6.8 6.5 6.5 0.2 3.5 3 1 2 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 RasGAP_C PF03836.15 EGG04735.1 - 4.5 7.4 11.3 0.31 11.2 0.4 2.5 2 1 0 2 2 2 0 RasGAP C-terminus CLZ PF16526.5 EGG04735.1 - 5 7.6 14.1 7 7.1 0.4 3.9 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RP-C_C PF11800.8 EGG04735.1 - 5.1 7.1 9.7 0.34 11.0 0.5 2.4 2 1 0 2 2 2 0 Replication protein C C-terminal region DUF3106 PF11304.8 EGG04735.1 - 5.4 7.5 10.5 0.49 10.9 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) ISG65-75 PF11727.8 EGG04735.1 - 6.4 5.9 12.6 1.1 8.5 5.2 2.3 2 1 0 2 2 2 0 Invariant surface glycoprotein DUF2203 PF09969.9 EGG04735.1 - 7.7 7.3 11.7 18 6.0 2.1 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.19 EGG04735.1 - 9.3 4.0 12.7 2 6.3 7.6 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family MPP6 PF10175.9 EGG04736.1 - 0.055 14.0 0.1 0.055 14.0 0.1 2.1 1 1 0 2 2 2 0 M-phase phosphoprotein 6 SAP18 PF06487.12 EGG04737.1 - 1.2e-31 109.8 0.0 1.6e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) FAD_binding_2 PF00890.24 EGG04738.1 - 3e-127 425.2 4.7 3.8e-127 424.9 4.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EGG04738.1 - 5.4e-44 149.3 0.3 7.9e-44 148.7 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 EGG04738.1 - 2e-05 24.0 0.3 0.02 14.1 0.1 2.6 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EGG04738.1 - 4.6e-05 22.7 2.0 0.011 14.8 2.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EGG04738.1 - 6.2e-05 22.4 0.4 0.0015 17.8 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGG04738.1 - 0.002 17.4 0.3 0.0041 16.4 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EGG04738.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 EGG04738.1 - 0.026 13.2 1.2 0.32 9.6 0.7 2.6 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 EGG04738.1 - 0.066 12.8 2.2 0.42 10.1 2.1 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGG04738.1 - 1.1 8.5 3.0 1.9 7.6 1.7 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YL1 PF05764.13 EGG04739.1 - 2.5 8.1 21.2 4.2 7.4 21.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SpoIIIAH PF12685.7 EGG04739.1 - 4.1 7.2 11.8 7.2 6.4 11.8 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein CDC45 PF02724.14 EGG04739.1 - 6.7 4.9 13.3 9.2 4.4 13.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_6 PF12697.7 EGG04741.1 - 3.5e-05 24.5 0.0 0.0002 22.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PhoPQ_related PF10142.9 EGG04741.1 - 5.1e-05 22.1 0.1 0.00012 20.9 0.0 1.6 2 0 0 2 2 2 1 PhoPQ-activated pathogenicity-related protein Citrate_synt PF00285.21 EGG04741.1 - 0.0013 17.9 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF2048 PF09752.9 EGG04741.1 - 0.051 12.7 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 DUF755 PF05501.11 EGG04746.1 - 0.00059 20.1 20.5 0.00059 20.1 20.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF755) GEMIN8 PF15348.6 EGG04746.1 - 0.022 15.1 3.1 0.4 11.0 0.5 2.6 3 0 0 3 3 3 0 Gemini of Cajal bodies-associated protein 8 SR-25 PF10500.9 EGG04746.1 - 2.2 7.8 27.7 0.03 13.9 19.2 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 EGG04746.1 - 5.9 7.8 9.9 0.3 12.0 3.2 2.2 2 0 0 2 2 2 0 Chorion family 2 RNase_H2_suC PF08615.11 EGG04747.1 - 4.1e-16 59.4 0.0 6.6e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) ERCC4 PF02732.15 EGG04748.1 - 7.6 6.7 12.5 0.2 11.8 0.2 2.8 2 1 0 3 3 3 0 ERCC4 domain HHH_2 PF12826.7 EGG04749.1 - 0.011 15.8 0.0 0.084 13.0 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif DEAD_2 PF06733.15 EGG04750.1 - 7.4e-53 178.8 0.0 1.3e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EGG04750.1 - 3.6e-46 157.3 0.6 1e-40 139.5 0.1 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EGG04750.1 - 1e-45 156.0 0.0 1.9e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 EGG04750.1 - 0.00011 22.2 0.0 0.0043 17.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG04750.1 - 0.0015 18.3 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 EGG04750.1 - 0.0025 16.6 0.0 0.3 9.8 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain DUF2075 PF09848.9 EGG04750.1 - 0.12 11.6 0.0 5.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Nop16 PF09420.10 EGG04751.1 - 2.8e-46 158.2 7.6 3.5e-46 157.9 7.6 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Cyclin PF08613.11 EGG04752.1 - 6.4e-41 140.4 0.0 1.6e-40 139.1 0.0 1.7 1 0 0 1 1 1 1 Cyclin 7tm_1 PF00001.21 EGG04753.1 - 9.6e-09 34.9 2.4 1.4e-08 34.4 2.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 EGG04753.1 - 0.00017 21.4 8.8 0.00029 20.7 5.4 2.6 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 DDHD PF02862.17 EGG04757.1 - 1.3e-32 113.7 4.8 1.5e-32 113.6 0.0 2.7 3 0 0 3 3 3 1 DDHD domain WWE PF02825.20 EGG04757.1 - 1.2 9.7 4.9 2.2 8.9 0.5 3.3 3 0 0 3 3 3 0 WWE domain AP3D1 PF06375.11 EGG04757.1 - 2.3 8.4 10.6 0.19 12.0 1.0 3.0 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 NAM-associated PF14303.6 EGG04760.1 - 0.016 15.9 6.5 0.14 12.9 6.5 1.9 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain EAP30 PF04157.16 EGG04760.1 - 0.03 13.6 0.1 0.037 13.3 0.1 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family MFS_1 PF07690.16 EGG04762.1 - 4.6e-35 121.2 11.8 4.6e-35 121.2 11.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MAP17 PF15807.5 EGG04762.1 - 0.0026 18.0 1.1 0.072 13.3 0.0 2.3 2 0 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 UNC-93 PF05978.16 EGG04762.1 - 0.67 9.7 10.5 0.091 12.5 5.2 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 WD40 PF00400.32 EGG04765.1 - 1.4e-09 38.4 0.4 0.00018 22.3 0.1 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG04765.1 - 1.7e-05 25.0 0.0 0.45 10.8 0.0 3.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 EGG04765.1 - 0.048 12.7 0.0 0.097 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Ge1_WD40 PF16529.5 EGG04765.1 - 0.076 12.0 0.0 2.1 7.2 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Abhydrolase_1 PF00561.20 EGG04767.1 - 7.1e-48 163.5 0.0 9.7e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG04767.1 - 0.00058 20.5 0.1 0.0011 19.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EGG04767.1 - 0.017 15.2 0.0 0.056 13.6 0.0 1.9 1 0 0 1 1 1 0 TAP-like protein Hydrolase_3 PF08282.12 EGG04769.1 - 8.4e-05 22.4 0.6 8.4e-05 22.4 0.6 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG04769.1 - 0.00017 22.0 0.0 0.00066 20.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGG04769.1 - 0.013 15.0 0.2 0.049 13.2 0.0 1.8 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Bac_transf PF02397.16 EGG04769.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial sugar transferase FadA PF09403.10 EGG04769.1 - 2.3 8.8 8.8 1.6 9.2 6.9 1.7 2 0 0 2 2 2 0 Adhesion protein FadA LYRIC PF15686.5 EGG04770.1 - 0.00016 21.4 1.4 0.00018 21.2 1.4 1.1 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family Pec_lyase_C PF00544.19 EGG04771.1 - 1.9e-12 47.3 1.9 4.4e-11 42.8 2.0 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EGG04771.1 - 0.00027 20.8 2.6 0.00066 19.6 2.6 1.7 1 1 0 1 1 1 1 Right handed beta helix region Sirohm_synth_M PF14824.6 EGG04771.1 - 1.4 8.4 6.4 1 8.9 0.3 2.4 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central Pec_lyase_C PF00544.19 EGG04772.1 - 0.0022 17.6 0.1 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 Pectate lyase Peptidase_M18 PF02127.15 EGG04773.1 - 1.6e-158 528.0 0.0 1.8e-158 527.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EGG04773.1 - 0.0042 16.2 0.0 0.012 14.6 0.0 1.7 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase DUF3069 PF11269.8 EGG04774.1 - 0.26 11.6 0.9 0.93 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) HSP90 PF00183.18 EGG04775.1 - 8.4e-154 513.3 14.0 8.4e-154 513.3 14.0 2.3 2 0 0 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.6 EGG04775.1 - 1.3e-09 38.0 0.1 5.5e-09 36.0 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGG04775.1 - 4.2e-06 27.2 0.0 1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DDHD PF02862.17 EGG04775.1 - 9 6.4 13.1 2.3 8.3 3.2 2.7 3 0 0 3 3 3 0 DDHD domain PNISR PF15996.5 EGG04778.1 - 3.3 7.9 19.7 0.68 10.2 1.0 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR PARM PF17061.5 EGG04778.1 - 7 6.7 11.3 8.7 6.4 11.3 1.1 1 0 0 1 1 1 0 PARM Cys_Met_Meta_PP PF01053.20 EGG04782.1 - 3.2e-52 177.3 0.0 1e-51 175.7 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RMI1_C PF16099.5 EGG04785.1 - 0.065 13.1 0.8 0.11 12.3 0.1 1.7 2 0 0 2 2 2 0 Recq-mediated genome instability protein 1, C-terminal OB-fold TMPIT PF07851.13 EGG04785.1 - 0.36 10.0 1.2 0.39 9.9 1.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS6_N PF14661.6 EGG04785.1 - 2 8.0 7.5 2.4 7.7 7.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF724 PF05266.14 EGG04785.1 - 4 7.2 9.0 9.3 6.0 8.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 EGG04785.1 - 7.3 6.8 7.8 5.3 7.2 0.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mis14 PF08641.12 EGG04786.1 - 0.00016 22.0 2.4 0.00061 20.1 0.1 2.4 3 0 0 3 3 3 1 Kinetochore protein Mis14 like ASFV_J13L PF05568.11 EGG04786.1 - 0.11 12.3 0.2 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Ge1_WD40 PF16529.5 EGG04788.1 - 9.5e-08 31.4 0.0 1.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyoxalase_2 PF12681.7 EGG04789.1 - 0.0017 18.3 0.0 0.66 9.9 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.25 EGG04789.1 - 0.0051 17.0 0.1 0.0094 16.1 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DAD PF02109.16 EGG04792.1 - 1.3e-42 144.5 2.0 1.4e-42 144.4 2.0 1.0 1 0 0 1 1 1 1 DAD family Egh16-like PF11327.8 EGG04793.1 - 2.4e-30 106.3 0.1 3e-30 106.0 0.1 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor SopE_GEF PF07487.13 EGG04793.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 SopE GEF domain Egh16-like PF11327.8 EGG04794.1 - 4.1e-30 105.6 0.2 1.8e-29 103.4 0.0 1.9 2 0 0 2 2 2 1 Egh16-like virulence factor PriCT_1 PF08708.11 EGG04794.1 - 0.039 13.7 1.0 12 5.7 0.0 2.8 2 1 0 2 2 2 0 Primase C terminal 1 (PriCT-1) MRP-S32 PF10210.9 EGG04794.1 - 5.8 7.5 7.9 5.5 7.6 0.8 2.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 FliD_N PF02465.18 EGG04798.1 - 0.018 15.7 4.5 0.018 15.7 4.5 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Sec20 PF03908.13 EGG04798.1 - 0.17 11.8 2.0 0.44 10.5 1.0 2.3 2 0 0 2 2 2 0 Sec20 DUF948 PF06103.11 EGG04800.1 - 0.021 15.0 0.6 0.038 14.2 0.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF5048 PF16467.5 EGG04802.1 - 0.11 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5048) Amidohydro_1 PF01979.20 EGG04805.1 - 1.2e-06 28.1 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Sporozoite_P67 PF05642.11 EGG04807.1 - 2.7 6.0 5.1 2.8 5.9 5.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribonuc_P_40 PF08584.11 EGG04808.1 - 0.14 11.4 3.2 0.27 10.5 1.0 2.3 2 0 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit DUF5427 PF10310.9 EGG04811.1 - 1.8 7.5 15.3 1.9 7.3 15.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) OPT PF03169.15 EGG04813.1 - 8.5e-158 526.8 40.3 9.7e-158 526.6 40.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Mito_carr PF00153.27 EGG04815.1 - 4.8e-47 157.8 1.4 6.8e-14 51.6 0.0 4.9 4 1 0 4 4 4 4 Mitochondrial carrier protein MCLC PF05934.11 EGG04816.1 - 0.11 11.3 3.3 0.17 10.6 3.3 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) HemY_N PF07219.13 EGG04816.1 - 1.7 8.8 3.5 1.1 9.5 0.3 2.4 2 0 0 2 2 2 0 HemY protein N-terminus Elong_Iki1 PF10483.9 EGG04817.1 - 0.0019 17.8 0.4 0.0027 17.3 0.4 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 RNA_pol_Rpc82 PF05645.13 EGG04818.1 - 0.012 15.3 2.6 0.014 15.2 2.6 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 Smg8_Smg9 PF10220.9 EGG04818.1 - 0.36 9.1 3.8 0.41 8.9 3.8 1.0 1 0 0 1 1 1 0 Smg8_Smg9 CxC5 PF18718.1 EGG04819.1 - 4.9e-22 78.2 25.5 3.3e-20 72.3 19.0 3.2 2 1 0 2 2 2 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG04819.1 - 2e-20 72.8 1.5 2e-20 72.8 1.5 2.1 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases BDV_P40 PF06407.11 EGG04821.1 - 0.17 10.9 0.1 0.19 10.8 0.1 1.0 1 0 0 1 1 1 0 Borna disease virus P40 protein Ras PF00071.22 EGG04822.1 - 0.0014 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Ras family LRRC37 PF15779.5 EGG04823.1 - 0.02 15.2 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat-containing protein 37 family LRR_4 PF12799.7 EGG04823.1 - 0.12 12.9 1.5 0.2 12.1 0.3 1.9 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Sporozoite_P67 PF05642.11 EGG04824.1 - 2.7 6.0 5.1 2.8 5.9 5.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAR1 PF03101.15 EGG04825.1 - 0.00045 20.9 0.0 0.00095 19.8 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Peptidase_C65 PF10275.9 EGG04825.1 - 0.0099 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain DUF948 PF06103.11 EGG04830.1 - 0.078 13.2 1.5 60 4.0 1.2 4.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) PsbP PF01789.16 EGG04830.1 - 0.23 11.6 1.0 0.65 10.1 0.1 2.2 2 1 0 2 2 2 0 PsbP MFS_1 PF07690.16 EGG04831.1 - 3.6e-23 82.1 20.8 8e-23 80.9 20.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1634 PF07843.11 EGG04831.1 - 0.0072 16.4 0.2 0.17 12.0 0.6 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1634) TRI12 PF06609.13 EGG04831.1 - 0.0088 14.5 1.2 0.013 13.9 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2615 PF11027.8 EGG04831.1 - 0.18 12.0 0.0 0.63 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) GST_N_3 PF13417.6 EGG04834.1 - 0.0019 18.6 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGG04834.1 - 0.0076 16.4 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG04834.1 - 0.0095 16.1 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.18 EGG04835.1 - 6.6e-07 29.4 8.4 6.6e-07 29.4 8.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MerR-DNA-bind PF09278.11 EGG04835.1 - 0.0057 17.2 0.6 0.015 15.8 0.6 1.7 1 0 0 1 1 1 1 MerR, DNA binding FAA_hydro_N_2 PF18288.1 EGG04837.1 - 0.12 12.9 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 RrnaAD PF00398.20 EGG04838.1 - 7.1e-63 212.2 0.1 9.1e-63 211.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGG04838.1 - 3.9e-07 30.7 0.0 6.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG04838.1 - 5.6e-05 23.7 0.0 9.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG04838.1 - 0.0001 23.0 0.0 0.00018 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG04838.1 - 0.00095 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGG04838.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EGG04838.1 - 0.0023 17.5 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_28 PF02636.17 EGG04838.1 - 0.0032 17.2 0.0 0.0076 15.9 0.0 1.6 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 EGG04838.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EGG04838.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 EGG04838.1 - 0.049 13.2 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Shikimate_DH PF01488.20 EGG04838.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DREV PF05219.12 EGG04838.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_31 PF13847.6 EGG04838.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.25 EGG04839.1 - 8.9e-09 35.1 0.4 1e-08 34.9 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG04839.1 - 0.0087 15.4 0.2 0.0089 15.3 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase GTP_cyclohydro2 PF00925.20 EGG04840.1 - 8.7e-60 201.0 0.0 1.1e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase II F-box-like PF12937.7 EGG04842.1 - 3.3e-05 23.7 1.8 0.0001 22.1 0.0 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EGG04842.1 - 0.025 14.5 0.3 0.78 9.7 0.1 3.1 2 1 0 2 2 2 0 F-box domain TRA-1_regulated PF02343.16 EGG04843.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 TRA-1 regulated protein R03H10.4 UCH PF00443.29 EGG04845.1 - 2.2e-39 135.5 0.0 4.5e-39 134.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EGG04845.1 - 4.6e-24 83.9 5.9 1.2e-23 82.6 0.8 3.2 3 0 0 3 3 3 1 Variant UBP zinc finger zf-UBP PF02148.19 EGG04845.1 - 2.5e-23 82.2 19.1 1.1e-18 67.3 6.0 3.1 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGG04845.1 - 4.8e-19 69.1 1.9 1.4e-16 61.0 0.1 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 EGG04845.1 - 1.7e-16 59.8 0.0 2.4e-07 30.5 0.0 2.7 3 0 0 3 3 3 2 UBA/TS-N domain Sec34 PF04136.15 EGG04847.1 - 0.073 13.0 2.6 0.18 11.7 0.1 2.7 4 0 0 4 4 4 0 Sec34-like family DUF2784 PF10861.8 EGG04847.1 - 0.23 11.5 0.0 0.43 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) Dicty_REP PF05086.12 EGG04848.1 - 0.38 8.7 2.1 0.71 7.8 2.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DDE_Tnp_4 PF13359.6 EGG04849.1 - 2.5e-25 89.0 0.0 3.3e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGG04849.1 - 0.00058 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain UCH PF00443.29 EGG04853.1 - 0.025 14.1 0.0 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Nup160 PF11715.8 EGG04854.1 - 2.8e-46 158.3 7.1 5.8e-46 157.2 7.1 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PYRIN PF02758.16 EGG04854.1 - 0.15 12.3 2.7 9.9 6.4 0.2 3.3 3 0 0 3 3 3 0 PAAD/DAPIN/Pyrin domain PPR PF01535.20 EGG04854.1 - 1.1 9.6 2.6 64 4.1 0.0 4.0 4 0 0 4 4 4 0 PPR repeat Carm_PH PF17888.1 EGG04855.1 - 0.099 13.0 0.1 0.15 12.5 0.1 1.4 1 1 0 1 1 1 0 Carmil pleckstrin homology domain DUF4065 PF13274.6 EGG04857.1 - 0.27 12.1 2.4 0.39 11.6 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4065) Macoilin PF09726.9 EGG04858.1 - 0.61 8.6 17.1 0.77 8.2 17.1 1.1 1 0 0 1 1 1 0 Macoilin family CBP4 PF07960.11 EGG04858.1 - 7.9 6.3 19.0 6.9 6.5 6.8 2.2 1 1 1 2 2 2 0 CBP4 GREB1 PF15782.5 EGG04858.1 - 9.3 3.2 14.3 11 3.0 14.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Fungal_trans PF04082.18 EGG04863.1 - 5.5e-17 61.7 1.2 7.1e-16 58.0 0.0 2.6 2 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGG04863.1 - 2.5e-05 24.3 4.3 5.3e-05 23.3 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Keratin_2_head PF16208.5 EGG04863.1 - 0.072 13.2 8.9 0.22 11.7 8.9 1.8 1 0 0 1 1 1 0 Keratin type II head KRTAP PF11759.8 EGG04863.1 - 0.49 11.0 12.5 1.1 9.9 12.5 1.5 1 0 0 1 1 1 0 Keratin-associated matrix Methyltransf_8 PF05148.15 EGG04864.1 - 1.8e-51 175.1 2.4 4.3e-28 98.7 2.4 3.3 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EGG04864.1 - 0.0043 17.7 0.0 0.075 13.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG04864.1 - 0.032 14.9 0.1 1 10.1 0.1 2.5 1 1 0 1 1 1 0 Methyltransferase domain CENP-B_dimeris PF09026.10 EGG04864.1 - 0.077 13.4 1.4 0.11 12.8 0.5 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CPSF100_C PF13299.6 EGG04864.1 - 0.65 10.2 6.6 3.5 7.8 0.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FAM176 PF14851.6 EGG04864.1 - 0.75 9.5 6.4 0.38 10.4 0.3 2.3 2 0 0 2 2 2 0 FAM176 family E7 PF00527.18 EGG04864.1 - 0.92 9.7 8.2 1.7 8.9 5.9 2.6 1 1 1 2 2 2 0 E7 protein, Early protein RPA43_OB PF17875.1 EGG04864.1 - 2.2 8.9 8.9 0.5 11.0 2.2 2.6 2 1 0 2 2 2 0 RPA43 OB domain in RNA Pol I Hydin_ADK PF17213.3 EGG04864.1 - 3.2 8.0 10.0 8.9 6.5 6.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain LNS2 PF08235.13 EGG04865.1 - 1.8e-102 341.6 0.0 3.3e-102 340.8 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EGG04865.1 - 1.9e-33 114.4 0.0 8.9e-33 112.3 0.0 2.0 1 1 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 EGG04865.1 - 0.0079 16.3 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Helicase_C PF00271.31 EGG04868.1 - 0.039 14.3 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain GF_recep_IV PF14843.6 EGG04870.1 - 0.097 12.5 0.5 0.19 11.6 0.1 1.6 2 0 0 2 2 2 0 Growth factor receptor domain IV DUF742 PF05331.11 EGG04870.1 - 0.19 11.6 2.6 0.36 10.7 2.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF742) YEATS PF03366.16 EGG04872.1 - 1.7e-29 101.6 0.0 3.5e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 YEATS family PLA2_B PF01735.18 EGG04873.1 - 7.3e-75 252.2 1.5 7.1e-72 242.4 1.5 2.2 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Lyase_aromatic PF00221.19 EGG04875.1 - 6.7e-145 483.3 3.3 8.6e-145 482.9 3.3 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Glycos_transf_2 PF00535.26 EGG04875.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Prefoldin PF02996.17 EGG04876.1 - 0.057 13.3 1.9 2.6 8.0 0.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit PA28_alpha PF02251.18 EGG04876.1 - 0.1 12.6 0.2 0.26 11.4 0.2 1.6 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit DUF4407 PF14362.6 EGG04876.1 - 0.23 10.8 3.8 0.22 10.8 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PhoD PF09423.10 EGG04877.1 - 6.6e-37 127.3 3.0 2.2e-36 125.6 3.0 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 EGG04877.1 - 0.025 15.1 0.0 0.064 13.8 0.0 1.7 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Translat_reg PF01818.17 EGG04879.1 - 0.069 13.1 0.2 0.98 9.4 0.0 2.6 3 0 0 3 3 3 0 Bacteriophage translational regulator Ndc1_Nup PF09531.10 EGG04879.1 - 0.93 8.1 8.3 1.3 7.6 8.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPF0564 PF10595.9 EGG04879.1 - 7.2 5.6 15.6 0.86 8.6 11.3 1.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 DUF3535 PF12054.8 EGG04881.1 - 5.3e-94 315.9 0.1 1.8e-92 310.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EGG04881.1 - 4.7e-67 226.2 0.1 7.1e-67 225.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG04881.1 - 2.4e-16 60.0 0.0 7.6e-16 58.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EGG04881.1 - 4.4e-15 54.5 7.4 0.9 10.0 0.0 8.9 8 0 0 8 8 8 5 HEAT repeat ResIII PF04851.15 EGG04881.1 - 4.8e-05 23.4 0.3 0.00035 20.6 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Vac14_Fab1_bd PF12755.7 EGG04881.1 - 0.00034 21.1 0.0 0.35 11.5 0.1 3.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EGG04881.1 - 0.00051 20.4 11.5 1.2 9.6 0.5 6.9 6 2 0 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 EGG04881.1 - 0.027 15.0 16.2 8.8 7.0 0.0 8.6 8 2 2 10 10 10 0 HEAT-like repeat DHR10 PF18595.1 EGG04882.1 - 6.8e-20 71.3 14.2 6.8e-20 71.3 14.2 4.0 1 1 3 4 4 4 1 Designed helical repeat protein 10 domain Nuf2 PF03800.14 EGG04882.1 - 1.9e-11 44.2 0.0 1.9e-11 44.2 0.0 2.4 3 1 0 3 3 3 1 Nuf2 family CLZ PF16526.5 EGG04882.1 - 0.07 13.5 0.7 0.07 13.5 0.7 4.9 3 2 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF948 PF06103.11 EGG04882.1 - 0.11 12.8 4.1 2.7 8.3 0.2 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 EGG04882.1 - 0.2 11.7 11.9 0.084 12.9 2.5 3.7 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Serine_rich PF08824.10 EGG04882.1 - 5.7 6.9 12.5 0.65 10.0 0.4 2.8 3 0 0 3 3 3 0 Serine rich protein interaction domain Tweety PF04906.13 EGG04882.1 - 7.1 5.2 9.2 9.7 4.7 3.1 2.5 1 1 1 2 2 2 0 Tweety Atg14 PF10186.9 EGG04882.1 - 7.3 5.6 36.9 4.5 6.3 18.2 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Imm25 PF15564.6 EGG04884.1 - 0.011 15.7 1.3 0.96 9.4 0.0 3.9 4 1 1 5 5 5 0 Immunity protein 25 Keratin_2_head PF16208.5 EGG04884.1 - 0.014 15.5 22.8 0.14 12.3 11.1 2.6 2 0 0 2 2 2 0 Keratin type II head PAXX PF15384.6 EGG04884.1 - 0.042 13.5 0.8 13 5.5 0.0 3.7 4 0 0 4 4 4 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 PXT1 PF15214.6 EGG04884.1 - 0.11 12.8 0.3 5.2 7.5 0.1 2.7 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 MspA PF09203.11 EGG04884.1 - 0.28 11.0 24.9 0.18 11.6 9.7 3.6 3 0 0 3 3 3 0 MspA KRTAP PF11759.8 EGG04884.1 - 0.41 11.2 16.9 0.64 10.6 6.4 2.4 2 0 0 2 2 2 0 Keratin-associated matrix Barstar PF01337.18 EGG04885.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Barstar (barnase inhibitor) DUF1681 PF07933.14 EGG04886.1 - 3.6e-54 182.5 0.0 4.2e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) zf-RING_4 PF14570.6 EGG04888.1 - 1.1 9.0 7.4 0.38 10.6 2.5 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain OMP_b-brl PF13505.6 EGG04889.1 - 0.0019 18.3 0.5 0.0068 16.6 0.2 2.0 2 0 0 2 2 2 1 Outer membrane protein beta-barrel domain PAXX PF15384.6 EGG04889.1 - 0.016 14.9 0.2 0.17 11.5 0.0 2.2 2 1 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Keratin_2_head PF16208.5 EGG04889.1 - 0.17 12.0 8.4 0.027 14.6 3.0 2.0 2 0 0 2 2 2 0 Keratin type II head PC-Esterase PF13839.6 EGG04893.1 - 2.5e-08 34.0 0.0 0.00054 19.8 0.0 2.9 2 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DHHC PF01529.20 EGG04894.1 - 1.2e-32 112.8 10.7 1.2e-32 112.8 10.7 2.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase Syndecan PF01034.20 EGG04894.1 - 0.17 11.8 1.1 0.41 10.6 1.1 1.5 1 0 0 1 1 1 0 Syndecan domain DUF5521 PF17659.1 EGG04894.1 - 0.22 9.4 3.0 0.27 9.0 3.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) MAT1 PF06391.13 EGG04894.1 - 0.27 11.0 7.4 0.43 10.4 7.4 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF962 PF06127.11 EGG04895.1 - 6.2e-26 90.3 2.6 9.3e-26 89.8 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) DUF3810 PF12725.7 EGG04895.1 - 0.1 11.9 0.6 0.2 11.0 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF1056 PF06341.11 EGG04895.1 - 0.14 12.5 0.1 0.14 12.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) SLATT_5 PF18160.1 EGG04895.1 - 0.31 10.4 2.3 3.7 6.8 1.2 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 FTR1 PF03239.14 EGG04896.1 - 4.6e-54 183.7 7.7 1.8e-53 181.7 7.7 1.7 1 1 0 1 1 1 1 Iron permease FTR1 family Herpes_glycop PF01528.16 EGG04896.1 - 6.9e-05 21.9 0.1 6.9e-05 21.9 0.1 1.9 2 0 0 2 2 2 1 Herpesvirus glycoprotein M InaF-motif PF15018.6 EGG04896.1 - 0.02 14.8 0.2 0.02 14.8 0.2 4.1 4 0 0 4 4 4 0 TRP-interacting helix DUF4199 PF13858.6 EGG04896.1 - 0.099 13.0 0.4 0.099 13.0 0.4 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4199) DUF3671 PF12420.8 EGG04896.1 - 0.31 11.1 0.1 0.31 11.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function GWT1 PF06423.12 EGG04896.1 - 0.55 10.4 0.0 0.55 10.4 0.0 2.6 3 0 0 3 3 3 0 GWT1 PDR_CDR PF06422.12 EGG04896.1 - 2.3 8.2 4.5 20 5.1 0.6 2.7 2 0 0 2 2 2 0 CDR ABC transporter BPD_transp_2 PF02653.16 EGG04896.1 - 7.9 5.5 23.0 0.25 10.4 13.9 2.6 2 2 1 3 3 3 0 Branched-chain amino acid transport system / permease component tRNA-synt_2b PF00587.25 EGG04898.1 - 3.9e-40 137.7 0.0 6.3e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGG04898.1 - 3.6e-18 65.5 0.1 7.1e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EGG04898.1 - 3.9e-13 49.2 0.0 8.9e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EGG04898.1 - 5.4e-06 26.4 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain PNP_UDP_1 PF01048.20 EGG04899.1 - 1e-27 96.9 0.0 1.4e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF1713 PF08213.11 EGG04900.1 - 0.014 15.3 4.6 0.031 14.2 4.6 1.6 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) Asp PF00026.23 EGG04901.1 - 1.9e-51 175.4 0.4 4.9e-44 151.0 0.3 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG04901.1 - 1.4e-12 48.2 2.5 5.9e-05 23.4 0.0 3.4 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGG04901.1 - 0.0025 18.4 0.5 0.89 10.2 0.0 3.2 2 1 0 2 2 2 1 Aspartyl protease Piwi PF02171.17 EGG04902.1 - 3e-60 204.0 0.0 4.9e-60 203.3 0.0 1.4 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EGG04902.1 - 4.4e-06 27.3 0.0 1.3e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 EGG04902.1 - 0.00014 22.0 0.0 0.00047 20.4 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 EGG04902.1 - 0.032 14.6 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 Argonaute linker 2 domain DUF3921 PF13060.6 EGG04902.1 - 0.072 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) ATG_C PF09333.11 EGG04903.1 - 0.059 13.7 0.0 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain GPI-anchored PF10342.9 EGG04905.1 - 1.4e-08 35.4 1.2 1.5e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AAA_19 PF13245.6 EGG04905.1 - 0.007 16.7 0.4 0.011 16.1 0.4 1.4 1 0 0 1 1 1 1 AAA domain UL20 PF17582.2 EGG04905.1 - 0.26 10.6 6.9 0.34 10.2 6.9 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL20 AAA_23 PF13476.6 EGG04905.1 - 0.36 11.3 1.4 0.47 10.9 1.4 1.2 1 0 0 1 1 1 0 AAA domain S100PBPR PF15427.6 EGG04905.1 - 0.58 9.4 3.1 0.76 9.0 3.1 1.1 1 0 0 1 1 1 0 S100P-binding protein AAA PF00004.29 EGG04906.1 - 2.4e-40 138.0 0.0 5.3e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGG04906.1 - 9.4e-19 67.1 0.1 1.9e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGG04906.1 - 3e-08 33.4 0.2 8e-08 32.0 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGG04906.1 - 4.8e-05 23.8 0.2 0.0081 16.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGG04906.1 - 0.00026 21.0 0.2 0.0033 17.4 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGG04906.1 - 0.00037 20.3 0.0 0.00089 19.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGG04906.1 - 0.00058 20.0 0.0 0.01 16.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGG04906.1 - 0.001 19.3 0.4 0.068 13.4 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG04906.1 - 0.0027 17.9 0.0 0.0071 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EGG04906.1 - 0.0032 16.9 0.1 0.024 14.1 0.1 2.1 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EGG04906.1 - 0.0056 16.1 0.5 0.018 14.4 0.1 2.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EGG04906.1 - 0.017 14.5 0.6 0.11 11.8 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF815 PF05673.13 EGG04906.1 - 0.018 14.2 0.0 0.034 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EGG04906.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1640 PF07798.11 EGG04906.1 - 0.047 13.7 1.6 0.097 12.7 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) AAA_24 PF13479.6 EGG04906.1 - 0.057 13.1 0.1 0.19 11.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGG04906.1 - 0.071 12.6 0.6 0.42 10.1 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EGG04906.1 - 0.11 12.2 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EGG04906.1 - 0.15 12.5 0.1 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 EGG04906.1 - 0.18 11.6 2.9 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain YabA PF06156.13 EGG04906.1 - 0.73 10.5 2.6 2.6 8.7 1.2 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Tetraspanin PF00335.20 EGG04907.1 - 0.0082 15.9 7.6 0.0082 15.9 7.6 1.3 1 1 0 1 1 1 1 Tetraspanin family Pex24p PF06398.11 EGG04907.1 - 0.035 13.1 0.4 0.046 12.7 0.4 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin CbtA PF09490.10 EGG04907.1 - 0.062 13.1 2.3 0.31 10.8 2.3 1.9 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) SID-1_RNA_chan PF13965.6 EGG04907.1 - 0.9 7.9 3.0 1.5 7.1 3.0 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PWI PF01480.17 EGG04908.1 - 5e-10 39.6 1.7 6.4e-10 39.2 0.2 2.0 2 0 0 2 2 2 1 PWI domain TMEM192 PF14802.6 EGG04908.1 - 0.13 11.3 1.8 0.27 10.3 1.8 1.4 1 0 0 1 1 1 0 TMEM192 family GCM PF03615.15 EGG04909.1 - 0.0014 18.5 2.1 0.02 14.8 0.8 2.5 2 0 0 2 2 2 1 GCM motif protein CIDE-N PF02017.15 EGG04909.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 CIDE-N domain PUFD PF16553.5 EGG04912.1 - 0.0071 16.5 0.2 0.017 15.3 0.2 1.6 1 0 0 1 1 1 1 BCORL-PCGF1-binding domain Neur_chan_memb PF02932.16 EGG04912.1 - 3.7 7.5 14.4 2.8 7.9 2.7 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Glyco_hydro_31 PF01055.26 EGG04913.1 - 7.2e-132 440.7 3.8 1e-131 440.2 3.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGG04913.1 - 3.3e-24 85.0 0.3 1.6e-23 82.8 0.0 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like PRKCSH-like PF12999.7 EGG04913.1 - 4.6e-12 46.1 5.6 8e-12 45.3 5.6 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like DUF5110 PF17137.4 EGG04913.1 - 4.7e-06 26.8 0.0 1.4e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Ldl_recept_a PF00057.18 EGG04913.1 - 0.63 10.3 9.8 1.5 9.1 9.8 1.7 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Glyco_hydro_31 PF01055.26 EGG04914.1 - 1.6e-112 376.9 4.8 2.5e-112 376.3 4.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGG04914.1 - 3.3e-28 97.8 0.7 2.1e-25 88.8 0.1 2.6 2 0 0 2 2 2 2 Galactose mutarotase-like PRKCSH_1 PF13015.6 EGG04915.1 - 2.5e-28 98.7 0.4 2.5e-28 98.7 0.4 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.7 EGG04915.1 - 3.1e-16 59.7 2.8 3.1e-16 59.7 2.8 2.2 2 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH PF07915.13 EGG04915.1 - 8.3e-06 26.7 3.0 2.5e-05 25.2 3.0 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 EGG04915.1 - 0.012 15.5 0.2 0.036 13.9 0.2 1.7 1 0 0 1 1 1 0 Autophagy-related protein 27 CHDCT2 PF08074.11 EGG04915.1 - 0.02 15.0 0.8 0.048 13.8 0.8 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Spc7 PF08317.11 EGG04915.1 - 0.04 12.8 8.7 0.091 11.6 5.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 EGG04915.1 - 0.32 11.4 0.2 0.32 11.4 0.2 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Ldl_recept_a PF00057.18 EGG04915.1 - 1.1 9.5 10.1 3.3 8.0 10.1 1.9 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A DUF4407 PF14362.6 EGG04915.1 - 2 7.7 5.2 8.6 5.6 5.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YnfE PF17452.2 EGG04915.1 - 2.1 8.7 7.3 2 8.8 0.1 3.0 2 1 1 3 3 3 0 Uncharacterized YnfE-like UPF0449 PF15136.6 EGG04915.1 - 2.5 8.6 8.3 0.35 11.4 3.3 2.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Med7 PF05983.11 EGG04915.1 - 2.9 7.9 7.5 0.95 9.5 1.1 2.3 2 0 0 2 2 2 0 MED7 protein BLOC1_2 PF10046.9 EGG04915.1 - 3.7 7.9 9.5 4 7.8 2.0 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 EGG04915.1 - 6.8 6.5 9.1 1.3 8.9 5.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) AA_permease PF00324.21 EGG04916.1 - 1.1e-123 413.4 35.6 1.3e-123 413.1 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGG04916.1 - 2.6e-32 112.2 39.6 3.3e-32 111.9 39.6 1.1 1 0 0 1 1 1 1 Amino acid permease Ank_4 PF13637.6 EGG04918.1 - 1.9e-13 50.6 0.2 8.6e-07 29.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG04918.1 - 2e-11 43.9 0.0 5.8e-08 32.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG04918.1 - 3.4e-10 40.4 0.0 4.4e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG04918.1 - 3.9e-07 29.9 0.0 0.0065 16.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EGG04918.1 - 1.8e-06 28.1 0.1 0.00024 21.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat SH3_1 PF00018.28 EGG04919.1 - 1.6e-14 53.2 0.0 5.8e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EGG04919.1 - 2.5e-09 36.9 0.0 0.0026 17.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 EGG04919.1 - 9.9e-06 25.2 0.0 0.0097 15.6 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain DEAD PF00270.29 EGG04920.1 - 2.6e-10 40.3 0.0 8.9e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG04920.1 - 2.7e-06 27.7 0.0 1.2e-05 25.5 0.0 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain CRAL_TRIO PF00650.20 EGG04921.1 - 8.2e-40 136.1 0.4 1.5e-39 135.3 0.4 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGG04921.1 - 3.8e-09 36.8 0.0 6.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGG04921.1 - 1.1e-08 35.1 0.2 3.2e-08 33.6 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Mito_carr PF00153.27 EGG04923.1 - 1.1e-54 182.3 6.1 2.5e-21 75.4 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGG04923.1 - 0.001 18.3 0.1 0.03 13.5 0.0 2.5 1 1 1 2 2 2 2 Gammaproteobacterial serine protease Med26 PF08711.11 EGG04924.1 - 0.026 14.5 0.3 0.13 12.3 0.0 2.3 2 0 0 2 2 2 0 TFIIS helical bundle-like domain THOC2_N PF16134.5 EGG04925.1 - 9e-118 394.6 0.1 1.7e-117 393.7 0.1 1.4 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EGG04925.1 - 5.8e-83 278.5 0.0 1.5e-82 277.2 0.0 1.7 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EGG04925.1 - 9.6e-29 99.3 0.1 2.6e-28 97.9 0.1 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Ribosomal_S25 PF03297.15 EGG04929.1 - 3.6e-38 129.8 4.3 4.3e-38 129.6 4.3 1.1 1 0 0 1 1 1 1 S25 ribosomal protein Imm19 PF15563.6 EGG04929.1 - 0.004 16.7 0.3 0.0046 16.5 0.3 1.1 1 0 0 1 1 1 1 Immunity protein 19 HTH_24 PF13412.6 EGG04929.1 - 0.02 14.4 0.2 0.038 13.5 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MerR_1 PF13411.6 EGG04929.1 - 0.046 13.8 0.1 0.069 13.2 0.1 1.2 1 0 0 1 1 1 0 MerR HTH family regulatory protein DUF2439 PF10382.9 EGG04929.1 - 2.3 8.6 6.0 5.4 7.4 6.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2439) NTF2 PF02136.20 EGG04931.1 - 3e-05 24.6 0.0 4.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4878 PF12870.7 EGG04931.1 - 0.0017 18.7 1.5 0.0027 18.0 1.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4878) Ras PF00071.22 EGG04932.1 - 2.9e-46 157.1 0.0 5.3e-46 156.2 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG04932.1 - 4.1e-33 114.1 0.0 6.7e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG04932.1 - 2.9e-15 56.2 0.0 4.6e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGG04932.1 - 2.4e-05 23.8 0.0 5.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGG04932.1 - 4.5e-05 22.9 0.0 6.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG04932.1 - 0.00038 20.5 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG04932.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGG04932.1 - 0.091 13.1 0.1 0.22 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain RAP1 PF07218.11 EGG04933.1 - 1.6 6.9 3.5 1.9 6.6 3.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) INO80_Ies4 PF08193.11 EGG04935.1 - 0.0073 16.3 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CDC27 PF09507.10 EGG04941.1 - 0.56 9.5 17.1 0.73 9.2 17.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ciart PF15673.5 EGG04941.1 - 1.5 8.2 4.6 0.17 11.2 0.6 1.5 2 0 0 2 2 2 0 Circadian-associated transcriptional repressor DUF3189 PF11385.8 EGG04943.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) DUF2806 PF10987.8 EGG04945.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) FAM72 PF14976.6 EGG04947.1 - 6.4e-21 75.0 1.6 1.2e-20 74.2 1.6 1.3 1 0 0 1 1 1 1 FAM72 protein DBR1 PF05011.13 EGG04947.1 - 0.14 12.6 0.1 0.26 11.7 0.1 1.4 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain Yippee-Mis18 PF03226.14 EGG04947.1 - 0.71 10.1 8.2 26 5.1 6.6 2.9 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Peptidase_C1_2 PF03051.15 EGG04948.1 - 1.2e-152 508.7 0.0 6.1e-152 506.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EGG04948.1 - 0.00014 22.0 0.1 0.13 12.3 0.0 2.5 2 0 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.13 EGG04948.1 - 0.046 12.9 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Phage portal protein, lambda family Dioxygenase_C PF00775.21 EGG04948.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Dioxygenase Peptidase_C1_2 PF03051.15 EGG04949.1 - 5.1e-159 529.7 0.1 1.9e-158 527.8 0.1 1.7 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EGG04949.1 - 2.7e-05 24.3 0.1 0.2 11.7 0.1 2.6 2 1 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGG04950.1 - 9.2e-138 459.7 0.0 5.6e-137 457.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase C1-like family DUF1661 PF07877.11 EGG04950.1 - 0.041 13.6 2.2 0.041 13.6 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) Peptidase_C1_2 PF03051.15 EGG04951.1 - 2e-124 415.7 0.0 5.9e-124 414.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase C1-like family zf-4CXXC_R1 PF10497.9 EGG04951.1 - 0.00022 21.4 13.0 0.00056 20.1 13.0 1.7 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 F-box-like PF12937.7 EGG04952.1 - 0.00018 21.3 2.0 0.0025 17.6 2.0 2.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EGG04952.1 - 7.9 6.5 7.3 0.47 10.4 0.7 2.5 3 0 0 3 3 3 0 F-box domain DUF1279 PF06916.13 EGG04953.1 - 3.1 8.4 5.4 7 7.3 3.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1279) zf-UBR PF02207.20 EGG04954.1 - 5.1e-17 61.8 19.9 5.1e-17 61.8 19.9 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EGG04954.1 - 1.1e-12 47.5 0.1 5.8e-10 38.8 0.0 2.7 2 0 0 2 2 2 2 ATP-dependent Clp protease adaptor protein ClpS ATP-synt_E PF05680.12 EGG04954.1 - 3.3 8.1 5.3 1.3 9.5 1.5 2.3 2 0 0 2 2 2 0 ATP synthase E chain Cu-oxidase_3 PF07732.15 EGG04955.1 - 1.8e-44 150.5 1.6 2.7e-42 143.6 0.6 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG04955.1 - 8.5e-29 100.0 2.9 5.3e-24 84.5 0.2 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGG04955.1 - 5.4e-28 98.1 0.1 7e-23 81.5 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase KH_1 PF00013.29 EGG04956.1 - 0.0022 17.8 0.3 0.006 16.4 0.3 1.7 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 EGG04956.1 - 0.0044 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain Rep_fac_C PF08542.11 EGG04957.1 - 3.6e-26 91.4 0.4 8.7e-26 90.2 0.1 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EGG04957.1 - 6.4e-12 45.5 0.1 9.8e-09 35.2 0.1 2.8 2 1 1 3 3 3 2 DNA polymerase III, delta subunit AAA PF00004.29 EGG04957.1 - 4.4e-10 40.1 0.0 8.9e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG04957.1 - 3.1e-06 27.7 0.0 0.00026 21.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EGG04957.1 - 3.7e-06 27.0 0.0 9.7e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGG04957.1 - 1.6e-05 25.2 0.1 0.015 15.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EGG04957.1 - 2e-05 24.5 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EGG04957.1 - 0.00072 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGG04957.1 - 0.00079 19.2 0.0 0.0022 17.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EGG04957.1 - 0.0015 18.3 0.0 0.004 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGG04957.1 - 0.0027 17.7 0.0 0.0079 16.1 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 EGG04957.1 - 0.0032 16.9 0.0 0.042 13.2 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 EGG04957.1 - 0.0037 17.6 0.1 0.032 14.6 0.1 2.4 1 1 0 1 1 1 1 AAA C-terminal domain AAA_5 PF07728.14 EGG04957.1 - 0.013 15.5 0.0 0.04 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 EGG04957.1 - 0.026 13.5 0.0 0.071 12.1 0.0 1.7 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 EGG04957.1 - 0.034 14.5 0.4 0.33 11.3 0.1 2.3 2 1 1 3 3 2 0 AAA domain NTPase_1 PF03266.15 EGG04957.1 - 0.035 14.0 0.2 0.12 12.2 0.1 2.0 1 1 1 2 2 2 0 NTPase TniB PF05621.11 EGG04957.1 - 0.036 13.5 0.0 8.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 EGG04957.1 - 0.044 13.4 0.2 0.14 11.7 0.1 1.8 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGG04957.1 - 0.051 13.8 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGG04957.1 - 0.051 13.4 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MipZ PF09140.11 EGG04957.1 - 0.055 12.7 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ FtsK_SpoIIIE PF01580.18 EGG04957.1 - 0.08 12.3 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family DEAD PF00270.29 EGG04957.1 - 0.095 12.5 0.4 1.8 8.3 0.0 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EGG04957.1 - 0.13 12.0 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sm_like PF16243.5 EGG04958.1 - 0.13 12.4 0.1 0.17 12.0 0.1 1.4 1 1 0 1 1 1 0 Sm_like domain CxC5 PF18718.1 EGG04959.1 - 6e-25 87.6 8.5 6e-25 87.6 8.5 2.1 2 0 0 2 2 2 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG04959.1 - 1.5e-08 34.8 1.1 1.5e-08 34.8 1.1 2.6 2 1 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases Cellulase PF00150.18 EGG04960.1 - 1e-17 64.5 0.5 1.6e-17 63.9 0.5 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Tmem26 PF09772.9 EGG04960.1 - 0.04 13.3 0.4 0.07 12.5 0.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 26 UL42 PF17638.2 EGG04960.1 - 0.077 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 HCMV UL42 vATP-synt_AC39 PF01992.16 EGG04960.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit eIF-6 PF01912.18 EGG04961.1 - 1.2e-80 269.5 0.2 1.7e-80 269.1 0.2 1.2 1 0 0 1 1 1 1 eIF-6 family KH_1 PF00013.29 EGG04962.1 - 7.2e-06 25.7 0.1 0.0067 16.2 0.0 2.3 2 0 0 2 2 2 2 KH domain Cation_ATPase_C PF00689.21 EGG04963.1 - 5.8e-46 156.5 8.6 5.8e-46 156.5 8.6 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGG04963.1 - 2.1e-38 131.7 0.7 2.1e-38 131.7 0.7 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGG04963.1 - 2.1e-18 66.2 0.2 5.1e-18 64.9 0.2 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGG04963.1 - 2.6e-15 55.9 0.1 8.8e-15 54.2 0.1 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EGG04963.1 - 2.1e-14 54.3 1.1 4.4e-13 50.0 1.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGG04963.1 - 0.026 14.3 0.3 0.08 12.7 0.1 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ferlin_C PF16165.5 EGG04963.1 - 0.12 12.4 0.3 0.71 9.8 0.0 2.5 2 0 0 2 2 2 0 Ferlin C-terminus BAR PF03114.18 EGG04964.1 - 2.9e-36 125.3 4.7 4.1e-36 124.8 4.7 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EGG04964.1 - 1.3e-13 50.3 0.1 2.1e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGG04964.1 - 4e-13 49.0 0.1 6.9e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGG04964.1 - 1.6e-09 37.3 0.1 2.9e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Fcf2 PF08698.11 EGG04966.1 - 6.8e-23 80.9 0.2 1e-22 80.3 0.2 1.3 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Nkap_C PF06047.11 EGG04967.1 - 8.2e-26 90.1 4.3 3.3e-25 88.2 4.3 1.8 1 1 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain Coprogen_oxidas PF01218.18 EGG04969.1 - 2.7e-137 456.4 0.0 3e-137 456.2 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Astro_capsid_p PF12226.8 EGG04970.1 - 0.029 13.5 2.6 0.05 12.7 2.6 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SBDS PF01172.18 EGG04972.1 - 1.1e-33 115.1 0.4 2.2e-33 114.2 0.2 1.6 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EGG04972.1 - 1.3e-32 112.2 0.2 2e-32 111.6 0.2 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain bVLRF1 PF18826.1 EGG04973.1 - 2e-09 37.5 0.0 3.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor DUF5304 PF17230.2 EGG04973.1 - 0.031 14.5 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5304) Aldo_ket_red PF00248.21 EGG04974.1 - 5e-17 62.0 0.0 6.6e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GYF PF02213.16 EGG04976.1 - 0.00056 19.5 0.4 0.0011 18.6 0.4 1.4 1 0 0 1 1 1 1 GYF domain eIF3m_C_helix PF18005.1 EGG04980.1 - 1.4e-09 37.4 0.1 2.1e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Chitin_synth_2 PF03142.15 EGG04980.1 - 0.025 13.2 0.0 0.026 13.1 0.0 1.0 1 0 0 1 1 1 0 Chitin synthase Cupin_4 PF08007.12 EGG04980.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Cupin superfamily protein Nkap_C PF06047.11 EGG04981.1 - 1.6e-44 150.2 3.5 1.6e-44 150.2 3.5 2.1 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain Macoilin PF09726.9 EGG04981.1 - 1.2 7.7 16.2 1.8 7.0 16.2 1.3 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 EGG04981.1 - 1.5 8.0 17.2 2.3 7.3 17.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SOBP PF15279.6 EGG04981.1 - 8.7 6.8 21.7 0.62 10.6 15.0 2.0 2 0 0 2 2 2 0 Sine oculis-binding protein NTF2 PF02136.20 EGG04983.1 - 0.011 16.3 0.3 0.033 14.7 0.1 1.8 1 1 1 2 2 2 0 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.6 EGG04985.1 - 0.065 13.4 0.0 0.083 13.0 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain DUF1616 PF07760.11 EGG04985.1 - 0.068 12.5 0.1 0.14 11.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1616) NTF2 PF02136.20 EGG04985.1 - 0.11 13.1 0.3 0.32 11.6 0.2 1.7 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain CBS PF00571.28 EGG04986.1 - 3.6e-24 85.0 5.3 1.2e-07 32.1 0.2 4.4 4 0 0 4 4 4 4 CBS domain Retrotran_gag_2 PF14223.6 EGG04987.1 - 0.00014 21.5 0.0 0.00033 20.3 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type F-box PF00646.33 EGG04987.1 - 0.024 14.5 0.4 4.2 7.4 0.0 3.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 EGG04987.1 - 0.027 14.4 0.2 0.14 12.1 0.2 2.3 1 1 0 1 1 1 0 F-box-like LRR_4 PF12799.7 EGG04988.1 - 3.5 8.2 18.5 8.1 7.0 0.2 5.7 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) zf-BED PF02892.15 EGG04989.1 - 0.00065 19.7 2.4 0.0048 16.9 2.4 2.1 1 1 0 1 1 1 1 BED zinc finger zf-primase PF09329.11 EGG04989.1 - 0.073 12.9 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Primase zinc finger DUF572 PF04502.13 EGG04993.1 - 3.5 7.2 10.9 4.8 6.7 10.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) WH1 PF00568.23 EGG04994.1 - 6.2e-11 42.2 0.0 1.1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 EGG04994.1 - 2e-08 34.5 0.0 5.4e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 EGG04994.1 - 0.00099 18.9 0.2 0.0023 17.7 0.2 1.7 1 0 0 1 1 1 1 WH2 motif DUF2633 PF11119.8 EGG04996.1 - 0.0067 16.3 1.9 0.016 15.1 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2633) DUF3278 PF11683.8 EGG04996.1 - 5.9 7.0 10.7 1.9 8.6 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3278) DUF1883 PF08980.10 EGG04997.1 - 0.044 13.7 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) Oxysterol_BP PF01237.18 EGG04998.1 - 2e-91 306.7 1.3 5.3e-89 298.6 1.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein AmpE PF17113.5 EGG05000.1 - 0.065 12.6 0.1 0.076 12.3 0.1 1.1 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE SCO1-SenC PF02630.14 EGG05003.1 - 2.1e-44 150.7 0.0 2.9e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 EGG05003.1 - 0.00013 22.2 0.0 0.00029 21.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EGG05003.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family zf-4CXXC_R1 PF10497.9 EGG05004.1 - 1.1e-06 28.7 11.2 3e-06 27.4 11.2 1.7 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Dicty_REP PF05086.12 EGG05005.1 - 6.9 4.5 8.0 8.6 4.2 8.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ras PF00071.22 EGG05006.1 - 3.3e-65 218.6 0.1 5.9e-65 217.8 0.1 1.4 1 1 1 2 2 2 1 Ras family Roc PF08477.13 EGG05006.1 - 1.3e-34 119.0 0.1 1.4e-33 115.6 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG05006.1 - 9.5e-14 51.2 0.0 1.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG05006.1 - 1.1e-06 28.3 0.3 3.6e-06 26.7 0.1 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG05006.1 - 8.7e-06 25.8 0.1 0.00027 21.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGG05006.1 - 1.5e-05 24.5 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGG05006.1 - 0.00011 22.2 0.1 0.27 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGG05006.1 - 0.0065 16.0 0.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 EGG05006.1 - 0.013 15.0 0.0 0.032 13.7 0.0 1.6 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGG05006.1 - 0.016 15.6 0.0 0.022 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 EGG05006.1 - 0.03 13.4 0.0 0.25 10.4 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 EGG05006.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 EGG05006.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Septin AAA PF00004.29 EGG05006.1 - 0.064 13.7 0.0 0.56 10.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGG05006.1 - 0.069 12.9 0.1 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGG05006.1 - 0.14 11.6 0.0 0.38 10.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Cullin PF00888.22 EGG05009.1 - 1.7e-139 466.3 4.8 2.3e-139 465.8 4.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGG05009.1 - 5.4e-22 77.6 1.4 5.4e-22 77.6 1.4 3.8 3 1 1 4 4 4 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 EGG05009.1 - 0.19 12.3 7.1 2 9.0 0.9 3.3 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal Cep57_MT_bd PF06657.13 EGG05009.1 - 0.54 10.7 4.3 0.66 10.5 0.1 3.0 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 SF3a60_bindingd PF12108.8 EGG05009.1 - 0.95 9.4 4.7 0.27 11.1 0.2 2.3 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain DUF3677 PF12432.8 EGG05009.1 - 4.8 7.6 7.0 1.7 9.0 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3677) RabGAP-TBC PF00566.18 EGG05010.1 - 1.2e-49 168.9 0.1 1.2e-49 168.9 0.1 2.7 3 0 0 3 3 3 1 Rab-GTPase-TBC domain APG6_N PF17675.1 EGG05010.1 - 0.0025 18.4 6.9 0.0025 18.4 6.9 3.1 3 0 0 3 3 3 1 Apg6 coiled-coil region VGPC1_C PF16799.5 EGG05010.1 - 0.0066 16.4 0.1 0.031 14.3 0.1 2.1 1 0 0 1 1 1 1 C-terminal membrane-localisation domain of ion-channel, VCN1 ADIP PF11559.8 EGG05010.1 - 0.016 15.3 5.0 0.016 15.3 5.0 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding HMMR_C PF15908.5 EGG05010.1 - 1 9.6 7.6 0.22 11.8 2.9 2.3 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal DUF3450 PF11932.8 EGG05010.1 - 9.2 5.5 11.1 0.13 11.5 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spore_YpjB PF09577.10 EGG05011.1 - 0.0012 18.7 0.5 0.0016 18.3 0.5 1.2 1 0 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) Nop14 PF04147.12 EGG05011.1 - 5.3 5.1 12.6 3.5 5.7 11.0 1.3 1 1 0 1 1 1 0 Nop14-like family Terminase_2 PF03592.16 EGG05018.1 - 0.11 13.0 0.0 5.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Terminase small subunit PQ-loop PF04193.14 EGG05019.1 - 5.5e-13 48.5 2.9 8.1e-13 47.9 2.9 1.3 1 0 0 1 1 1 1 PQ loop repeat eIF-5a PF01287.20 EGG05020.1 - 0.0061 16.6 0.0 0.0086 16.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold FAM176 PF14851.6 EGG05021.1 - 0.088 12.5 2.6 0.1 12.3 2.6 1.1 1 0 0 1 1 1 0 FAM176 family UPF0239 PF06783.11 EGG05021.1 - 0.47 10.7 2.7 0.69 10.1 2.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Connexin PF00029.19 EGG05021.1 - 0.48 10.2 6.4 0.56 9.9 6.4 1.0 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 EGG05021.1 - 1.7 7.6 3.6 1.8 7.5 3.6 1.0 1 0 0 1 1 1 0 CLN3 protein DUF4820 PF16091.5 EGG05021.1 - 2.4 7.5 5.3 2.8 7.2 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Presenilin PF01080.17 EGG05021.1 - 3.3 6.4 9.9 3.4 6.3 9.9 1.0 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 EGG05021.1 - 4.5 5.1 10.2 4.8 5.0 10.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAP17 PF15807.5 EGG05021.1 - 5.3 7.3 10.0 6.5 7.0 10.0 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 ALMT PF11744.8 EGG05021.1 - 5.3 5.7 8.7 5.7 5.7 8.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SF-assemblin PF06705.11 EGG05024.1 - 0.079 12.3 0.4 0.15 11.4 0.4 1.4 1 0 0 1 1 1 0 SF-assemblin/beta giardin THF_DHG_CYH_C PF02882.19 EGG05024.1 - 0.17 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CDC45 PF02724.14 EGG05025.1 - 1.5 7.1 3.8 1.7 6.9 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop25 PF09805.9 EGG05026.1 - 0.16 12.4 9.3 0.23 11.9 9.3 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Pox_Ag35 PF03286.14 EGG05028.1 - 0.95 9.2 8.1 1.1 9.1 7.5 1.4 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Activator_LAG-3 PF11498.8 EGG05030.1 - 0.065 12.2 0.0 0.086 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CDP-OH_P_transf PF01066.21 EGG05032.1 - 1.3e-07 32.2 0.6 1.7e-07 31.9 0.6 1.3 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Josephin PF02099.17 EGG05032.1 - 0.06 13.4 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Josephin ArsA_ATPase PF02374.15 EGG05033.1 - 6.1e-112 373.7 0.1 7e-112 373.5 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EGG05033.1 - 2.5e-12 47.1 0.0 1.1e-11 45.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EGG05033.1 - 3.4e-12 46.5 0.0 6.9e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 EGG05033.1 - 3.5e-05 23.4 0.1 0.00014 21.4 0.0 1.9 3 0 0 3 3 3 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 EGG05033.1 - 4.5e-05 23.0 0.1 0.00027 20.5 0.0 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EGG05033.1 - 4.9e-05 22.9 0.0 0.00013 21.5 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EGG05033.1 - 0.00061 19.5 0.0 0.0087 15.7 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EGG05033.1 - 0.0093 15.6 0.5 0.073 12.6 0.5 2.2 1 1 0 1 1 1 1 AAA domain VirC1 PF07015.11 EGG05033.1 - 0.042 13.1 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein AAA_24 PF13479.6 EGG05033.1 - 0.072 12.8 0.0 0.2 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EGG05033.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 EGG05033.1 - 0.17 11.1 0.0 0.41 9.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DNA_primase_lrg PF04104.14 EGG05036.1 - 4e-80 269.0 0.0 5.9e-80 268.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Lyase_catalyt PF09093.11 EGG05036.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Lyase, catalytic DUF3736 PF12540.8 EGG05038.1 - 0.017 15.2 0.8 0.045 13.9 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) PspB PF06667.12 EGG05038.1 - 0.16 12.0 0.8 0.49 10.5 0.8 1.8 1 0 0 1 1 1 0 Phage shock protein B Glyco_hydro_125 PF06824.11 EGG05038.1 - 0.38 9.6 2.7 14 4.4 0.0 2.8 3 0 0 3 3 3 0 Metal-independent alpha-mannosidase (GH125) cNMP_binding PF00027.29 EGG05042.1 - 5.1e-37 125.8 0.7 6.7e-18 64.6 0.2 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RtcB PF01139.17 EGG05042.1 - 0.017 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB PgdA_N PF18627.1 EGG05042.1 - 0.16 11.6 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 Peptidoglycan GlcNAc deacetylase N-terminal domain Noc2 PF03715.13 EGG05047.1 - 5.4e-118 393.6 4.8 1e-117 392.7 1.0 2.7 3 0 0 3 3 3 1 Noc2p family ANAPC4_WD40 PF12894.7 EGG05048.1 - 4.9e-08 33.2 0.0 0.0023 18.2 0.0 3.1 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG05048.1 - 1.6e-06 28.7 0.0 1.5 9.8 0.2 3.8 3 1 0 3 3 3 3 WD domain, G-beta repeat MFS_1 PF07690.16 EGG05049.1 - 6.7e-41 140.4 53.8 1.6e-40 139.1 51.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG05049.1 - 9e-13 47.9 35.3 1.2e-11 44.1 14.6 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 EGG05049.1 - 0.0018 17.7 12.6 0.0018 17.7 12.6 3.2 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB Pex24p PF06398.11 EGG05049.1 - 3.7 6.4 7.9 2.2 7.2 3.0 2.2 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin MFS_1 PF07690.16 EGG05050.1 - 7.3e-43 146.8 40.3 1.2e-42 146.1 40.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG05050.1 - 8.4e-11 41.4 31.1 9.2e-08 31.4 13.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter CUE PF02845.16 EGG05051.1 - 1.8e-05 24.3 0.0 0.00038 20.1 0.0 2.3 2 0 0 2 2 2 1 CUE domain CitT PF12431.8 EGG05051.1 - 0.039 14.3 0.6 2.5 8.5 0.1 3.0 2 0 0 2 2 2 0 Transcriptional regulator RNA_polI_A14 PF08203.11 EGG05051.1 - 9.1 7.1 7.2 13 6.6 0.0 3.2 2 1 1 3 3 3 0 Yeast RNA polymerase I subunit RPA14 GPI-anchored PF10342.9 EGG05053.1 - 0.0037 18.0 0.0 0.0077 17.0 0.0 1.6 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FMN_red PF03358.15 EGG05054.1 - 4.4e-09 36.3 0.0 6.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGG05054.1 - 0.0021 17.8 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold His_Phos_1 PF00300.22 EGG05055.1 - 2.6e-41 141.5 0.0 3.1e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GET2 PF08690.10 EGG05057.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Poxvirus_B22R_N PF13169.6 EGG05057.1 - 0.031 14.8 0.1 0.053 14.0 0.1 1.5 1 1 0 1 1 1 0 Poxvirus B22R protein N-terminal HTH_21 PF13276.6 EGG05058.1 - 0.028 14.6 0.3 0.078 13.1 0.3 1.7 1 0 0 1 1 1 0 HTH-like domain Neur PF00064.18 EGG05060.1 - 0.031 13.1 0.1 0.12 11.1 0.0 1.9 1 1 0 1 1 1 0 Neuraminidase DUF3572 PF12096.8 EGG05060.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) DUF620 PF04788.12 EGG05060.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF620) Med3 PF11593.8 EGG05060.1 - 5 6.2 8.4 7.2 5.7 8.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal UvrD_C_2 PF13538.6 EGG05062.1 - 3.9e-05 23.4 0.0 9.1e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EGG05062.1 - 0.006 14.6 0.0 0.0068 14.4 0.0 1.0 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 EGG05062.1 - 0.041 13.6 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SWIM PF04434.17 EGG05064.1 - 7e-09 35.2 4.3 0.0026 17.4 0.0 2.5 2 0 0 2 2 2 2 SWIM zinc finger DUF1924 PF09086.11 EGG05064.1 - 0.046 14.1 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) DUF3195 PF11424.8 EGG05065.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGG05065.1 - 0.12 11.3 0.2 0.14 11.1 0.2 1.1 1 0 0 1 1 1 0 NUC194 domain LRR_6 PF13516.6 EGG05072.1 - 1e-14 53.3 25.5 0.0049 16.8 0.4 10.2 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.7 EGG05072.1 - 4.9e-06 26.8 23.5 0.0026 18.2 1.4 7.0 4 3 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG05072.1 - 0.0041 16.8 26.5 0.18 11.6 0.5 6.9 5 3 1 6 6 6 2 Leucine rich repeat Phage_head_fibr PF11133.8 EGG05072.1 - 0.039 13.4 0.2 0.068 12.6 0.2 1.3 1 0 0 1 1 1 0 Head fiber protein LRR_1 PF00560.33 EGG05072.1 - 0.042 14.4 17.1 93 4.2 0.0 9.0 9 0 0 9 9 9 0 Leucine Rich Repeat RdRP PF05183.12 EGG05073.1 - 6.5e-171 569.9 0.0 9.4e-171 569.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Hexokinase_2 PF03727.16 EGG05074.1 - 2.1e-83 279.5 0.0 2.8e-83 279.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGG05074.1 - 4.2e-69 232.4 0.0 6.5e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase RTTN_N PF14726.6 EGG05075.1 - 0.011 16.6 1.7 2.4 9.0 0.7 2.4 1 1 1 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning DUF4306 PF14154.6 EGG05075.1 - 0.073 13.2 0.3 4.5 7.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) Luciferase_3H PF10284.9 EGG05075.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Luciferase helical bundle domain AhpC-TSA PF00578.21 EGG05077.1 - 1.5e-20 73.3 0.0 3.2e-20 72.3 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 EGG05077.1 - 2.5e-11 43.5 0.0 3.9e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EGG05077.1 - 0.0027 17.8 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Ndc1_Nup PF09531.10 EGG05077.1 - 3.8 6.1 7.1 3.7 6.1 7.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 EGG05077.1 - 4.1 6.5 4.9 5.6 6.1 4.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PIN_4 PF13638.6 EGG05079.1 - 1.2e-21 77.4 0.4 3.1e-21 76.0 0.4 1.8 1 0 0 1 1 1 1 PIN domain PIN_9 PF18477.1 EGG05079.1 - 0.13 12.5 0.5 1.3 9.4 0.1 2.4 1 1 1 2 2 2 0 PIN like domain SCNM1_acidic PF15805.5 EGG05080.1 - 0.042 13.6 1.4 3.2 7.6 0.5 2.5 2 0 0 2 2 2 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 ATG13 PF10033.9 EGG05081.1 - 1.3e-39 136.3 0.0 1.8e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 Dus PF01207.17 EGG05082.1 - 4.6e-55 186.9 0.0 9.3e-55 185.9 0.0 1.4 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) IF-2B PF01008.17 EGG05083.1 - 2.9e-49 167.8 0.0 3.5e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family TrbI_Ftype PF09677.10 EGG05083.1 - 0.1 12.9 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) DeoRC PF00455.22 EGG05083.1 - 0.12 12.3 0.4 0.31 10.9 0.4 1.7 1 1 0 1 1 1 0 DeoR C terminal sensor domain Pyrophosphatase PF00719.19 EGG05084.1 - 3.6e-59 199.1 0.1 4.7e-59 198.8 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF4082 PF13313.6 EGG05085.1 - 0.023 14.8 1.2 1.1 9.3 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4082) Ribosomal_S8 PF00410.19 EGG05087.1 - 6.6e-23 81.0 0.1 1.2e-22 80.2 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 WD40 PF00400.32 EGG05088.1 - 6.6e-48 159.7 11.3 2.4e-11 44.0 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EGG05088.1 - 3.5e-28 98.4 0.0 6.5e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EGG05088.1 - 3.8e-12 46.3 0.2 0.0055 17.0 0.0 5.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG05088.1 - 2.5e-05 23.8 0.0 0.09 12.1 0.0 2.8 3 0 0 3 3 3 2 WD40-like domain eIF2A PF08662.11 EGG05088.1 - 3.5e-05 23.8 0.0 0.00032 20.6 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGG05088.1 - 0.0013 17.8 0.1 2.1 7.2 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGG05088.1 - 0.008 14.9 0.2 25 3.3 0.0 3.7 2 1 2 4 4 4 0 Nucleoporin Nup120/160 LisH PF08513.11 EGG05088.1 - 0.0099 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 LisH zf-C3HC4_2 PF13923.6 EGG05089.1 - 4.1e-08 32.9 2.3 3e-06 26.9 0.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG05089.1 - 5.4e-08 32.7 2.7 9e-08 32.0 2.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGG05089.1 - 1.6e-07 31.1 5.5 8.9e-07 28.7 5.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG05089.1 - 1.6e-07 31.5 2.8 4.8e-07 30.0 2.8 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGG05089.1 - 2.1e-07 30.7 0.3 4e-07 29.8 0.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG05089.1 - 4.4e-06 26.6 0.9 4.4e-06 26.6 0.9 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGG05089.1 - 1.8e-05 24.5 3.8 0.0033 17.2 2.1 2.2 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 Trypan_PARP PF05887.11 EGG05089.1 - 0.0056 16.6 8.5 0.0056 16.6 8.5 1.5 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF1631 PF07793.11 EGG05089.1 - 0.016 13.7 2.2 0.015 13.7 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Pex14_N PF04695.13 EGG05089.1 - 0.67 10.6 7.3 0.85 10.3 7.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C3HC4_4 PF15227.6 EGG05089.1 - 0.9 9.8 8.2 0.87 9.8 2.9 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING RP-C_C PF11800.8 EGG05089.1 - 6 6.9 7.7 11 6.0 7.7 1.5 1 1 0 1 1 1 0 Replication protein C C-terminal region CCDC53 PF10152.9 EGG05089.1 - 9.9 6.6 9.4 13 6.2 9.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Prenyltransf PF01255.19 EGG05091.1 - 0.037 13.5 0.1 7.1 6.1 0.0 2.7 3 0 0 3 3 3 0 Putative undecaprenyl diphosphate synthase FluMu_N PF17891.1 EGG05091.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain PIG-L PF02585.17 EGG05093.1 - 1.7e-17 64.3 0.0 2.9e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ApbA_C PF08546.11 EGG05094.1 - 7e-21 74.7 0.0 1.1e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EGG05094.1 - 8e-21 74.3 0.0 3.8e-20 72.1 0.0 1.9 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA PP2C PF00481.21 EGG05094.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C AF-4 PF05110.13 EGG05095.1 - 0.04 12.0 5.3 0.054 11.6 5.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NSP2-B_epitope PF14757.6 EGG05095.1 - 0.18 11.5 4.7 0.27 10.9 4.7 1.2 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein SR-25 PF10500.9 EGG05095.1 - 0.9 9.1 4.9 1.2 8.7 4.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ank_4 PF13637.6 EGG05096.1 - 0.00031 21.2 0.0 0.019 15.5 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG05096.1 - 0.0069 17.0 0.1 0.014 15.9 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGG05096.1 - 0.0094 16.4 0.2 0.084 13.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EGG05096.1 - 0.062 13.6 0.0 0.86 10.0 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) SOG2 PF10428.9 EGG05097.1 - 0.049 12.8 10.7 0.061 12.5 10.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_S8 PF00082.22 EGG05098.1 - 9e-31 107.2 4.1 1.5e-30 106.5 4.1 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGG05098.1 - 5.1e-06 27.1 0.6 1.2e-05 25.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 zf-RING_11 PF17123.5 EGG05099.1 - 9.5e-07 28.5 4.5 2.7e-06 27.0 4.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGG05099.1 - 1.9e-05 24.9 7.5 1.9e-05 24.9 7.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3H2C3 PF17122.5 EGG05099.1 - 0.002 18.1 6.4 0.0046 17.0 6.4 1.6 1 0 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 EGG05099.1 - 0.0021 18.0 7.9 0.0043 17.0 7.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EGG05099.1 - 0.0038 16.8 4.1 0.0072 15.9 4.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EGG05099.1 - 0.03 14.2 7.0 0.068 13.0 7.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF678 PF05077.12 EGG05099.1 - 0.067 13.3 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Endonuclease_7 PF02945.15 EGG05099.1 - 0.095 12.6 1.9 0.19 11.7 1.9 1.4 1 0 0 1 1 1 0 Recombination endonuclease VII zf-C3HC4_3 PF13920.6 EGG05099.1 - 0.15 12.0 5.9 0.2 11.6 4.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HscB_4_cys PF18256.1 EGG05099.1 - 0.44 10.4 2.9 0.96 9.3 2.9 1.6 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif DUF3523 PF12037.8 EGG05100.1 - 0.05 13.0 1.0 0.073 12.4 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) zf-RING_11 PF17123.5 EGG05101.1 - 1.7e-06 27.7 3.2 4.1e-06 26.4 3.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGG05101.1 - 7.1e-05 23.1 2.0 7.1e-05 23.1 2.0 2.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG05101.1 - 0.066 13.1 2.0 0.16 11.8 2.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG05101.1 - 0.59 10.2 2.7 1.3 9.1 2.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger ATP_bind_3 PF01171.20 EGG05102.1 - 5e-17 62.2 0.0 1.2e-16 61.0 0.0 1.6 2 0 0 2 2 2 1 PP-loop family zn-ribbon_14 PF16503.5 EGG05102.1 - 2.6e-11 42.8 4.3 2.6e-11 42.8 4.3 3.1 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 EGG05102.1 - 0.0032 16.3 0.0 0.0045 15.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase TSKS PF15358.6 EGG05102.1 - 0.063 11.6 0.2 0.11 10.8 0.2 1.3 1 0 0 1 1 1 0 Testis-specific serine kinase substrate PAPS_reduct PF01507.19 EGG05102.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family RNB PF00773.19 EGG05103.1 - 3.1e-51 174.6 0.0 5.9e-51 173.7 0.0 1.5 1 0 0 1 1 1 1 RNB domain Ubiquitin_4 PF18036.1 EGG05104.1 - 0.063 13.3 0.4 0.24 11.5 0.2 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain YicC_N PF03755.13 EGG05104.1 - 0.066 13.7 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 YicC-like family, N-terminal region Macoilin PF09726.9 EGG05106.1 - 0.14 10.7 3.4 0.16 10.5 3.4 1.0 1 0 0 1 1 1 0 Macoilin family CI-B14_5a PF07347.12 EGG05106.1 - 0.18 11.7 1.2 0.85 9.5 0.1 2.4 2 1 1 3 3 3 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) ATP_transf PF09830.9 EGG05107.1 - 1.3e-18 66.9 0.0 2.6e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase TPR_8 PF13181.6 EGG05108.1 - 0.057 13.7 3.0 9 6.8 0.3 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR_2 PF13041.6 EGG05108.1 - 0.13 12.5 0.5 30 4.9 0.1 3.9 4 0 0 4 4 4 0 PPR repeat family TPR_1 PF00515.28 EGG05108.1 - 0.13 12.1 0.8 44 4.1 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG05108.1 - 0.34 11.1 1.1 80 3.7 0.2 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 EGG05108.1 - 0.93 9.9 7.0 51 4.4 0.1 5.4 7 0 0 7 7 7 0 PPR repeat Zn_clus PF00172.18 EGG05109.1 - 0.00055 20.0 2.2 0.0014 18.7 2.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EGG05113.1 - 2.7e-55 187.6 0.0 3.3e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG05113.1 - 4.1e-25 88.6 0.0 7.4e-25 87.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG05113.1 - 1.4e-06 27.9 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGG05113.1 - 0.001 18.1 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGG05113.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG05113.1 - 0.048 13.6 0.0 0.08 12.9 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family BROMI PF14961.6 EGG05114.1 - 0.29 8.5 0.2 0.38 8.1 0.2 1.0 1 0 0 1 1 1 0 Broad-minded protein Glyco_hydro_43 PF04616.14 EGG05115.1 - 1e-37 130.0 2.2 1.3e-37 129.7 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_62 PF03664.13 EGG05115.1 - 0.0021 17.4 0.6 0.0028 17.0 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 VraX PF17412.2 EGG05116.1 - 0.022 14.4 0.4 0.67 9.6 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function zf-RING_2 PF13639.6 EGG05117.1 - 2.6e-06 27.6 6.9 7e-06 26.3 6.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGG05117.1 - 0.0065 16.2 3.4 0.017 14.9 3.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EGG05117.1 - 0.02 14.9 5.8 0.085 12.9 5.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGG05117.1 - 0.038 13.9 6.5 0.083 12.9 6.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGG05117.1 - 1.2 9.0 5.6 2.7 7.9 5.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RecR PF02132.15 EGG05117.1 - 1.3 8.6 6.5 0.34 10.5 0.7 2.5 2 0 0 2 2 2 0 RecR protein zf-C3HC4 PF00097.25 EGG05117.1 - 4.9 7.1 7.1 12 5.8 7.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Aminotran_1_2 PF00155.21 EGG05118.1 - 2.9e-26 92.5 0.0 3.6e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II AA_permease PF00324.21 EGG05119.1 - 2.4e-128 428.7 36.6 3e-128 428.4 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGG05119.1 - 7.3e-36 123.9 39.2 9.6e-36 123.5 39.2 1.2 1 0 0 1 1 1 1 Amino acid permease RNA_pol_Rpb4 PF03874.16 EGG05120.1 - 2.6e-17 63.3 0.0 3.4e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1059 PF06348.11 EGG05120.1 - 0.099 12.9 0.7 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) UNC-50 PF05216.13 EGG05121.1 - 6.8e-76 254.7 17.6 8.9e-76 254.3 17.6 1.1 1 0 0 1 1 1 1 UNC-50 family Scramblase PF03803.15 EGG05122.1 - 1.2e-57 194.7 0.0 1.6e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Scramblase F-box PF00646.33 EGG05123.1 - 0.0084 16.0 0.1 2.7 8.0 0.0 2.6 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 EGG05123.1 - 0.066 13.1 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 F-box-like BIR PF00653.21 EGG05124.1 - 5e-30 104.0 4.0 1e-15 58.1 0.6 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Ribosomal_L44 PF00935.19 EGG05127.1 - 5.4e-37 126.1 11.3 8.8e-37 125.4 11.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 EGG05127.1 - 0.049 14.0 0.5 0.092 13.1 0.5 1.4 1 0 0 1 1 1 0 Cathelicidin Baculo_gp64 PF03273.13 EGG05128.1 - 0.15 10.9 1.5 0.24 10.1 1.5 1.4 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family YlbE PF14003.6 EGG05129.1 - 0.044 14.2 3.1 0.074 13.5 3.1 1.3 1 0 0 1 1 1 0 YlbE-like protein APS_kinase PF01583.20 EGG05132.1 - 1.4e-66 223.3 0.0 1.7e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 EGG05132.1 - 8.3e-07 29.6 0.1 1.3e-06 29.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG05132.1 - 1.2e-06 28.7 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EGG05132.1 - 5.4e-05 23.2 0.0 7.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 EGG05132.1 - 7.6e-05 22.3 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 SRP54 PF00448.22 EGG05132.1 - 0.00077 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PRK PF00485.18 EGG05132.1 - 0.0039 17.0 0.0 0.0081 15.9 0.0 1.5 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EGG05132.1 - 0.0053 17.1 0.1 0.01 16.2 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EGG05132.1 - 0.0085 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 EGG05132.1 - 0.0089 15.8 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain PEPCK_ATP PF01293.20 EGG05132.1 - 0.0097 14.6 0.1 0.012 14.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase SWI2_SNF2 PF18766.1 EGG05132.1 - 0.016 14.9 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_31 PF13614.6 EGG05132.1 - 0.018 14.9 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGG05132.1 - 0.02 15.3 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EGG05132.1 - 0.03 14.8 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 EGG05132.1 - 0.041 12.9 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EGG05132.1 - 0.054 13.4 0.6 0.39 10.6 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EGG05132.1 - 0.055 13.2 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EGG05132.1 - 0.099 12.7 0.8 3.8 7.5 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain CLP1_P PF16575.5 EGG05132.1 - 0.16 11.8 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PH PF00169.29 EGG05133.1 - 5.5e-34 116.8 4.8 4.9e-19 68.8 1.1 2.5 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 EGG05133.1 - 9.5e-17 61.4 13.4 9.9e-08 32.4 0.1 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 EGG05133.1 - 3.1e-12 46.5 11.2 1.1e-07 31.9 2.2 3.2 3 0 0 3 3 3 3 PH domain PH_8 PF15409.6 EGG05133.1 - 1.3e-07 31.8 10.0 3.6e-06 27.2 1.8 3.1 2 1 1 3 3 3 2 Pleckstrin homology domain PH_13 PF16652.5 EGG05133.1 - 5.9e-07 29.4 1.3 0.0019 18.0 0.4 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 EGG05133.1 - 2.4e-06 27.9 4.2 0.026 14.9 0.0 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH_15 PF17339.2 EGG05133.1 - 0.00069 19.5 4.3 0.0085 16.0 1.7 2.3 2 0 0 2 2 2 1 PH domain PH_2 PF08458.10 EGG05133.1 - 0.0016 18.8 0.8 1.4 9.3 0.1 2.5 2 0 0 2 2 2 2 Plant pleckstrin homology-like region PH_4 PF15404.6 EGG05133.1 - 0.0089 15.8 2.7 2.4 7.9 0.1 3.5 2 1 1 3 3 3 1 Pleckstrin homology domain PH_6 PF15406.6 EGG05133.1 - 0.015 15.5 0.1 0.18 12.1 0.0 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain His_binding PF02098.16 EGG05133.1 - 0.12 12.4 3.5 1.8 8.6 0.3 2.9 3 0 0 3 3 3 0 Tick histamine binding protein VEFS-Box PF09733.9 EGG05133.1 - 3.6 7.4 6.1 1.7 8.4 0.8 2.3 2 0 0 2 2 2 0 VEFS-Box of polycomb protein Mito_carr PF00153.27 EGG05134.1 - 7.2e-45 150.9 0.0 7.6e-22 77.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L14e PF01929.17 EGG05135.1 - 1.9e-29 102.0 1.2 2.6e-29 101.5 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 DUF1053 PF06327.14 EGG05137.1 - 0.032 14.8 0.7 0.032 14.8 0.7 1.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1053) Peptidase_M32 PF02074.15 EGG05140.1 - 0.081 11.7 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase His_Phos_1 PF00300.22 EGG05141.1 - 2.7e-14 53.3 0.1 5.1e-14 52.4 0.1 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Phage_base_V PF04717.12 EGG05141.1 - 0.051 13.5 0.7 0.08 12.9 0.1 1.6 2 0 0 2 2 2 0 Type VI secretion system, phage-baseplate injector DER1 PF04511.15 EGG05142.1 - 1.3e-32 113.3 0.2 1.7e-32 112.9 0.2 1.1 1 0 0 1 1 1 1 Der1-like family BRO1 PF03097.18 EGG05143.1 - 4.4e-15 55.4 0.0 6.1e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain bZIP_1 PF00170.21 EGG05145.1 - 1.2e-06 28.5 11.7 1.7e-06 28.0 7.2 2.7 2 1 1 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 EGG05145.1 - 3.8e-06 26.9 4.6 3.8e-06 26.9 4.6 2.7 2 1 2 4 4 4 1 Basic region leucine zipper Yuri_gagarin PF15934.5 EGG05145.1 - 0.005 16.7 2.7 0.0093 15.8 2.7 1.3 1 0 0 1 1 1 1 Yuri gagarin MscS_porin PF12795.7 EGG05145.1 - 0.0054 16.3 2.9 0.0054 16.3 2.9 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain CASP_C PF08172.12 EGG05145.1 - 0.0066 15.8 1.3 0.016 14.6 1.1 1.7 1 1 0 1 1 1 1 CASP C terminal KASH_CCD PF14662.6 EGG05145.1 - 0.01 15.6 3.6 0.01 15.6 3.6 1.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 EGG05145.1 - 0.016 15.4 1.3 0.046 14.0 0.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper YabA PF06156.13 EGG05145.1 - 0.017 15.8 1.3 0.017 15.8 1.3 2.2 2 1 0 2 2 2 0 Initiation control protein YabA TolA_bind_tri PF16331.5 EGG05145.1 - 0.017 15.2 0.6 0.14 12.3 0.1 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation DivIC PF04977.15 EGG05145.1 - 0.026 14.3 0.7 0.067 13.0 0.7 1.7 1 0 0 1 1 1 0 Septum formation initiator Phage_GP20 PF06810.11 EGG05145.1 - 0.051 13.4 1.6 0.11 12.3 1.6 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 SlyX PF04102.12 EGG05145.1 - 0.075 13.7 2.7 0.33 11.6 1.4 2.8 2 1 0 2 2 2 0 SlyX RNase_HII PF01351.18 EGG05145.1 - 0.081 12.8 2.0 0.55 10.0 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease HII bZIP_Maf PF03131.17 EGG05145.1 - 0.14 12.7 4.7 0.32 11.5 4.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor FlaC_arch PF05377.11 EGG05145.1 - 0.18 12.2 2.7 1.4 9.4 0.6 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) EzrA PF06160.12 EGG05145.1 - 0.22 9.6 6.1 0.059 11.5 3.0 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA PGBA_C PF15437.6 EGG05145.1 - 0.48 10.8 4.8 0.42 11.0 3.2 1.8 2 0 0 2 2 1 0 Plasminogen-binding protein pgbA C-terminal Spc7 PF08317.11 EGG05145.1 - 1.1 8.1 10.1 0.071 12.0 4.6 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein zf-C4H2 PF10146.9 EGG05145.1 - 1.6 9.0 7.2 0.33 11.2 3.6 1.6 2 0 0 2 2 2 0 Zinc finger-containing protein RAC_head PF16717.5 EGG05145.1 - 1.8 9.6 7.0 0.43 11.6 3.1 1.9 2 0 0 2 2 2 0 Ribosome-associated complex head domain DUF1664 PF07889.12 EGG05145.1 - 2 8.5 4.1 5.7 7.0 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2205 PF10224.9 EGG05145.1 - 2.2 8.3 6.9 1.6 8.8 3.6 2.4 2 1 0 2 2 2 0 Short coiled-coil protein BST2 PF16716.5 EGG05145.1 - 2.8 8.6 6.0 0.71 10.5 1.9 2.0 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 zf-PARP PF00645.18 EGG05148.1 - 9e-18 64.9 5.6 7.7e-16 58.7 5.6 2.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Exo70 PF03081.15 EGG05149.1 - 2.9e-51 174.7 0.1 1.5e-50 172.4 0.0 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit CorA PF01544.18 EGG05149.1 - 0.016 14.5 0.4 0.87 8.8 0.0 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.10 EGG05149.1 - 0.13 12.4 0.6 0.77 9.9 0.2 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family APG17 PF04108.12 EGG05149.1 - 0.19 10.8 1.0 6.6 5.7 0.3 2.5 2 0 0 2 2 2 0 Autophagy protein Apg17 Sec3_C PF09763.9 EGG05149.1 - 0.45 8.8 4.5 0.46 8.8 0.2 2.8 3 1 1 4 4 4 0 Exocyst complex component Sec3 Baculo_PEP_C PF04513.12 EGG05149.1 - 0.94 9.5 4.8 2.2 8.3 3.8 2.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus UBN_AB PF14075.6 EGG05150.1 - 7.7e-31 107.5 0.7 7.7e-31 107.5 0.7 1.8 2 0 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 EGG05150.1 - 5.3e-10 39.1 0.0 5.3e-10 39.1 0.0 2.4 2 0 0 2 2 2 1 HPC2 and ubinuclein domain DUF702 PF05142.12 EGG05151.1 - 0.034 14.6 4.0 0.071 13.6 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) CARMIL_C PF16000.5 EGG05151.1 - 0.52 9.9 11.4 0.1 12.2 2.9 2.2 2 0 0 2 2 2 0 CARMIL C-terminus UBN_AB PF14075.6 EGG05154.1 - 6.6e-07 29.3 0.5 1.2e-06 28.4 0.5 1.4 1 0 0 1 1 1 1 Ubinuclein conserved middle domain SUZ PF12752.7 EGG05158.1 - 3.6e-09 37.2 0.0 3.6e-09 37.2 0.0 3.5 3 2 0 3 3 3 1 SUZ domain CFIA_Pcf11 PF11526.8 EGG05158.1 - 0.011 16.2 0.4 0.011 16.2 0.4 2.0 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 DUF2476 PF10630.9 EGG05159.1 - 0.025 14.7 0.3 0.025 14.7 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2476) USP7_ICP0_bdg PF12436.8 EGG05160.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 DUF4692 PF15763.5 EGG05160.1 - 2.6 8.5 12.3 9.5 6.7 0.0 4.2 4 0 0 4 4 4 0 Regulator of human erythroid cell expansion (RHEX) LSM PF01423.22 EGG05162.1 - 2.6e-14 52.6 0.2 3.6e-14 52.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGG05162.1 - 0.0012 18.9 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EGG05162.1 - 0.1 12.7 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Cep3 PF16846.5 EGG05163.1 - 0.0058 15.2 0.1 0.022 13.3 0.0 1.9 2 1 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit B Zn_clus PF00172.18 EGG05163.1 - 0.015 15.4 4.4 0.041 14.0 4.4 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DLEU7 PF15760.5 EGG05164.1 - 0.046 13.2 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Leukemia-associated protein 7 RhoGAP PF00620.27 EGG05165.1 - 2.4e-31 108.6 0.0 5.6e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RGS PF00615.19 EGG05168.1 - 4.7e-05 23.6 0.0 4.7e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain DnaJ PF00226.31 EGG05172.1 - 5.1e-13 49.0 0.0 1.2e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 EGG05173.1 - 0.00038 21.2 0.2 0.17 12.8 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40 PF00400.32 EGG05174.1 - 4.7e-10 39.9 8.4 0.0052 17.6 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG05174.1 - 9e-10 38.7 0.0 0.14 12.5 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG05174.1 - 0.058 13.3 0.3 0.56 10.1 0.0 2.6 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A CBF_beta PF02312.17 EGG05174.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Core binding factor beta subunit AAA PF00004.29 EGG05175.1 - 2.3e-17 63.6 0.0 3.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG05175.1 - 5e-14 53.0 0.0 2.4e-13 50.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGG05175.1 - 1.5e-08 35.0 0.0 7.2e-08 32.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 EGG05175.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_lid_10 PF17872.1 EGG05175.1 - 7.9e-05 22.7 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain ATPase_2 PF01637.18 EGG05175.1 - 0.00052 20.0 0.0 0.0016 18.4 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 EGG05175.1 - 0.00063 19.6 0.1 0.0053 16.6 0.1 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_19 PF13245.6 EGG05175.1 - 0.001 19.4 0.1 0.008 16.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EGG05175.1 - 0.0055 16.0 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 EGG05175.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EGG05175.1 - 0.047 13.8 0.0 8 6.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 EGG05175.1 - 0.051 13.5 0.3 0.13 12.1 0.2 1.7 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 EGG05175.1 - 0.071 13.5 0.0 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_3 PF07726.11 EGG05175.1 - 0.1 12.5 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EGG05175.1 - 0.11 11.8 0.0 0.3 10.5 0.0 1.6 1 1 0 1 1 1 0 Bacterial TniB protein AAA_30 PF13604.6 EGG05175.1 - 0.24 11.1 0.0 0.47 10.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pyridoxal_deC PF00282.19 EGG05176.1 - 3.2e-62 210.4 0.0 4.5e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain CsbD PF05532.12 EGG05176.1 - 3.4e-14 52.5 12.8 2.6e-09 36.8 3.9 2.4 1 1 1 2 2 2 2 CsbD-like MIP PF00230.20 EGG05177.1 - 5.4e-26 91.7 10.8 6.4e-26 91.5 10.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Pyridoxal_deC PF00282.19 EGG05178.1 - 7.4e-57 192.8 0.0 1.1e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGG05178.1 - 0.023 13.6 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGG05179.1 - 1.8e-37 129.4 0.0 2.1e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II ANAPC4_WD40 PF12894.7 EGG05180.1 - 0.0059 16.9 0.0 0.18 12.1 0.0 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG05180.1 - 0.12 13.3 0.0 1 10.3 0.0 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat COG4 PF08318.12 EGG05181.1 - 0.0082 15.3 0.2 0.0094 15.1 0.2 1.1 1 0 0 1 1 1 1 COG4 transport protein MPDZ_u10 PF16667.5 EGG05182.1 - 6.3 7.8 9.8 5.1 8.1 0.1 3.8 3 1 1 4 4 4 0 Unstructured region 10 on multiple PDZ protein SNF2_N PF00176.23 EGG05183.1 - 1.8e-44 151.9 0.9 2e-44 151.8 0.9 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGG05183.1 - 2e-07 30.9 0.0 2.5e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGG05183.1 - 3e-07 30.6 0.0 3.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGG05183.1 - 0.00081 19.1 0.0 0.001 18.8 0.0 1.3 1 1 0 1 1 1 1 SWI2/SNF2 ATPase Helicase_C PF00271.31 EGG05184.1 - 4.4e-15 56.0 0.0 7.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PPDK_N PF01326.19 EGG05184.1 - 0.091 12.0 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Endonuclease_NS PF01223.23 EGG05186.1 - 3.9e-56 190.4 0.0 5.8e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease KH_8 PF17903.1 EGG05187.1 - 4.1e-31 106.9 0.1 9.7e-31 105.7 0.1 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EGG05187.1 - 0.0012 18.7 0.1 0.0032 17.3 0.1 1.8 1 0 0 1 1 1 1 KH domain Amidohydro_1 PF01979.20 EGG05188.1 - 9.3e-60 202.7 0.0 1.8e-59 201.8 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGG05188.1 - 0.00052 19.6 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family CTP_transf_1 PF01148.20 EGG05190.1 - 8.5e-63 212.6 23.8 2.7e-62 211.0 23.8 1.7 1 1 0 1 1 1 1 Cytidylyltransferase family RRM_1 PF00076.22 EGG05191.1 - 5.9e-11 42.0 0.2 3.4e-05 23.6 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG05191.1 - 7.2e-05 22.8 0.0 0.00025 21.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif Vpu PF00558.19 EGG05191.1 - 0.35 10.6 2.4 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Vpu protein Endonuc_Holl PF10107.9 EGG05191.1 - 2.3 8.1 8.5 16 5.3 3.5 2.4 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase PX PF00787.24 EGG05194.1 - 1.5e-25 89.3 0.1 2.1e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 PX domain Adeno_E1B_19K PF01691.16 EGG05194.1 - 0.2 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen CDC27 PF09507.10 EGG05195.1 - 9.3e-08 31.9 0.0 9.3e-08 31.9 0.0 3.7 1 1 2 3 3 3 1 DNA polymerase subunit Cdc27 DUF2201_N PF13203.6 EGG05195.1 - 0.55 9.8 9.4 2 8.0 5.5 2.4 1 1 1 2 2 2 0 Putative metallopeptidase domain Xrn1_D3 PF18194.1 EGG05197.1 - 0.063 13.4 0.1 0.69 10.1 0.1 2.2 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 DUF3862 PF12978.7 EGG05197.1 - 0.066 13.0 0.2 0.35 10.7 0.0 2.1 2 1 1 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3862) ALS_ss_C PF10369.9 EGG05198.1 - 1.6e-15 57.1 0.0 6.7e-14 51.9 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EGG05198.1 - 1.8e-12 46.8 0.1 3.4e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EGG05198.1 - 3.1e-07 30.1 0.0 5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 ACT domain RED_N PF07808.13 EGG05201.1 - 2.6e-20 73.0 4.2 2.6e-20 73.0 4.2 2.2 2 0 0 2 2 2 1 RED-like protein N-terminal region PUMA PF15826.5 EGG05201.1 - 0.031 14.5 3.7 0.17 12.1 0.1 2.4 2 0 0 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis CxC5 PF18718.1 EGG05202.1 - 2e-23 82.7 2.5 4e-23 81.7 2.5 1.5 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG05202.1 - 4.7e-17 62.0 2.0 7e-17 61.5 0.2 2.3 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases Alpha_kinase PF02816.18 EGG05203.1 - 1.2e-12 48.3 2.3 1.2e-12 48.3 2.3 2.0 3 0 0 3 3 3 1 Alpha-kinase family Zip PF02535.22 EGG05203.1 - 0.2 10.8 3.4 0.24 10.6 3.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter zf-CCHC PF00098.23 EGG05204.1 - 0.0016 18.5 0.5 0.0031 17.5 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Alpha_kinase PF02816.18 EGG05205.1 - 0.0001 22.5 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family DUF3439 PF11921.8 EGG05208.1 - 0.055 13.4 0.5 0.1 12.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FAD_binding_4 PF01565.23 EGG05209.1 - 1.4e-25 89.7 2.4 2.1e-25 89.1 2.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGG05209.1 - 2.6e-14 53.0 1.3 4.6e-14 52.2 1.3 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EGG05209.1 - 0.09 12.2 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding CxC5 PF18718.1 EGG05212.1 - 1.8e-28 99.0 8.4 2.8e-28 98.4 8.4 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Transp_cyt_pur PF02133.15 EGG05212.1 - 0.11 11.3 0.1 0.19 10.5 0.1 1.3 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin Mis12 PF05859.12 EGG05214.1 - 3.7e-19 69.1 0.3 7.3e-19 68.2 0.3 1.6 1 0 0 1 1 1 1 Mis12 protein DUF3496 PF12001.8 EGG05214.1 - 0.02 15.3 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) NYD-SP28_assoc PF14775.6 EGG05214.1 - 0.025 14.7 1.8 0.22 11.6 0.5 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain Robl_LC7 PF03259.17 EGG05215.1 - 9.1e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EGG05215.1 - 0.076 12.9 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Ragulator complex protein LAMTOR5 Catalase PF00199.19 EGG05216.1 - 5.5e-178 591.9 0.0 6.6e-178 591.7 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGG05216.1 - 1.1e-13 51.1 0.0 2.2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Egh16-like PF11327.8 EGG05219.1 - 6.3e-26 91.9 1.9 6.3e-26 91.9 1.9 1.4 2 0 0 2 2 2 1 Egh16-like virulence factor RF-1 PF00472.20 EGG05219.1 - 0.09 12.7 0.6 0.16 11.9 0.6 1.3 1 0 0 1 1 1 0 RF-1 domain POTRA_2 PF08479.11 EGG05219.1 - 0.17 11.7 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 POTRA domain, ShlB-type Uds1 PF15456.6 EGG05222.1 - 2e-07 31.2 11.0 4.1e-05 23.7 7.4 10.5 3 2 7 10 10 10 2 Up-regulated During Septation FlxA PF14282.6 EGG05222.1 - 0.0045 17.0 6.4 0.0045 17.0 6.4 8.9 5 3 4 9 9 9 1 FlxA-like protein Spc7 PF08317.11 EGG05222.1 - 0.12 11.2 103.7 0.39 9.6 11.1 5.4 3 1 3 6 6 6 0 Spc7 kinetochore protein Nup54_57_C PF18570.1 EGG05222.1 - 0.26 10.9 3.0 1.8 8.3 0.4 3.4 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain Exonuc_VII_S PF02609.16 EGG05222.1 - 9.3 6.4 17.5 2.6 8.2 1.0 5.1 4 0 0 4 4 4 0 Exonuclease VII small subunit JTB PF05439.12 EGG05223.1 - 7.5e-06 26.0 0.1 7.5e-06 26.0 0.1 2.0 2 1 1 3 3 3 1 Jumping translocation breakpoint protein (JTB) COesterase PF00135.28 EGG05224.1 - 1.6e-76 258.3 0.0 1.8e-76 258.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG05224.1 - 6.4e-09 36.0 0.0 2.7e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG05224.1 - 1.2e-05 24.9 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EGG05224.1 - 0.0028 17.3 0.0 0.0068 16.1 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Say1_Mug180 PF10340.9 EGG05224.1 - 0.032 13.1 0.1 0.17 10.7 0.0 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase Abhydrolase_1 PF00561.20 EGG05224.1 - 0.054 13.1 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 EGG05225.1 - 2.2e-75 254.5 0.0 2.5e-75 254.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG05225.1 - 1.4e-05 25.0 0.0 3.8e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG05225.1 - 3.8e-05 23.3 0.0 6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EGG05225.1 - 0.0028 17.4 0.0 0.0066 16.1 0.0 1.4 1 1 0 1 1 1 1 Putative esterase HAD PF12710.7 EGG05225.1 - 0.14 12.6 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase COesterase PF00135.28 EGG05226.1 - 1.6e-67 228.6 0.0 2.1e-67 228.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG05226.1 - 4.2e-05 23.5 0.0 0.0001 22.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG05226.1 - 0.0015 18.0 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EGG05226.1 - 0.0054 16.4 0.0 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Say1_Mug180 PF10340.9 EGG05226.1 - 0.014 14.3 0.1 0.033 13.1 0.0 1.6 2 0 0 2 2 2 0 Steryl acetyl hydrolase HATPase_c PF02518.26 EGG05229.1 - 4e-23 82.0 0.0 7.8e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG05229.1 - 3.5e-18 65.4 0.1 1e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 EGG05229.1 - 1.3e-09 38.2 0.3 2.3e-09 37.4 0.3 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_3 PF13589.6 EGG05229.1 - 0.0011 18.8 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EGG05229.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DnaJ_C PF01556.18 EGG05230.1 - 2.1e-22 79.8 0.0 2.8e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGG05230.1 - 8.3e-20 70.7 2.4 1.5e-19 69.8 2.4 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGG05230.1 - 1.1e-10 41.7 8.1 1.8e-10 41.1 8.1 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EGG05230.1 - 0.11 12.5 4.5 1.6 8.8 0.4 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TSKS PF15358.6 EGG05230.1 - 0.19 10.1 0.0 0.26 9.6 0.0 1.2 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Anti-TRAP PF15777.5 EGG05230.1 - 0.6 10.1 7.8 1.9 8.5 0.2 3.0 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_C7 PF14522.6 EGG05230.1 - 1.8 8.6 7.1 1.4 9.0 3.4 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Viral_P18 PF04521.13 EGG05232.1 - 0.18 11.6 4.2 0.075 12.8 0.5 2.2 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein EOS1 PF12326.8 EGG05232.1 - 1.1 9.2 2.9 2 8.3 2.9 1.5 1 0 0 1 1 1 0 N-glycosylation protein Zip PF02535.22 EGG05232.1 - 2.7 7.1 4.7 3.9 6.6 4.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 EGG05232.1 - 4.9 6.9 15.0 1.2 8.9 12.0 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Alk_phosphatase PF00245.20 EGG05233.1 - 2.6e-84 283.6 0.0 3e-84 283.4 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Mpv17_PMP22 PF04117.12 EGG05235.1 - 2e-20 72.7 0.0 6.3e-20 71.2 0.0 1.9 1 0 0 1 1 1 1 Mpv17 / PMP22 family Sugar_tr PF00083.24 EGG05236.1 - 2.6e-110 369.4 25.7 3.1e-110 369.1 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG05236.1 - 1.1e-15 57.4 37.9 6.9e-11 41.7 10.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGG05236.1 - 0.00026 19.4 1.0 0.00026 19.4 1.0 2.4 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family AAA PF00004.29 EGG05237.1 - 9.6e-44 149.0 0.0 2e-43 148.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG05237.1 - 2.5e-13 49.6 0.1 5.9e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGG05237.1 - 1.4e-07 31.8 0.0 2.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGG05237.1 - 2.6e-06 27.5 0.0 1e-05 25.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGG05237.1 - 5.3e-06 26.9 0.0 6.6e-05 23.4 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 EGG05237.1 - 6.8e-06 26.0 0.2 1.7e-05 24.7 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EGG05237.1 - 1.3e-05 25.5 0.3 0.0052 17.1 0.1 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EGG05237.1 - 9.3e-05 22.2 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGG05237.1 - 0.00032 21.2 0.1 0.022 15.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 EGG05237.1 - 0.0014 17.9 0.0 0.0029 16.8 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGG05237.1 - 0.0016 18.6 0.0 0.0035 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGG05237.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EGG05237.1 - 0.0083 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGG05237.1 - 0.0085 15.5 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EGG05237.1 - 0.009 15.5 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 EGG05237.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGG05237.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 KaiC KLRAQ PF10205.9 EGG05237.1 - 0.021 15.0 0.6 0.021 15.0 0.6 1.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein AAA_24 PF13479.6 EGG05237.1 - 0.022 14.5 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGG05237.1 - 0.023 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EGG05237.1 - 0.026 14.2 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 EGG05237.1 - 0.032 13.4 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EGG05237.1 - 0.036 13.6 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGG05237.1 - 0.049 14.0 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EGG05237.1 - 0.049 13.7 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGG05237.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RILP PF11461.8 EGG05237.1 - 0.066 13.4 1.0 0.14 12.4 1.0 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein DUF2072 PF09845.9 EGG05237.1 - 0.069 13.4 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_25 PF13481.6 EGG05237.1 - 0.072 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DivIC PF04977.15 EGG05237.1 - 0.075 12.8 1.2 0.22 11.3 1.2 1.7 1 0 0 1 1 1 0 Septum formation initiator Zeta_toxin PF06414.12 EGG05237.1 - 0.088 12.1 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Cas_Csy4 PF09618.10 EGG05237.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) AAA_19 PF13245.6 EGG05237.1 - 0.11 12.8 0.0 0.53 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGG05237.1 - 0.14 12.1 0.0 0.7 9.8 0.0 2.0 1 1 0 2 2 2 0 NACHT domain CENP-X PF09415.10 EGG05239.1 - 8.9e-16 58.0 0.0 1.4e-15 57.3 0.0 1.4 1 1 0 1 1 1 1 CENP-S associating Centromere protein X AAA PF00004.29 EGG05240.1 - 1.6e-11 44.7 0.0 4e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGG05240.1 - 1.6e-05 25.2 0.1 5.7e-05 23.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EGG05240.1 - 6.3e-05 23.2 0.0 0.00038 20.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGG05240.1 - 6.8e-05 22.9 0.1 0.00061 19.8 0.0 2.4 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_14 PF13173.6 EGG05240.1 - 0.0001 22.3 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGG05240.1 - 0.00011 22.0 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGG05240.1 - 0.0002 21.5 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 EGG05240.1 - 0.00042 20.1 0.1 0.00075 19.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGG05240.1 - 0.00044 20.3 0.0 0.00085 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 EGG05240.1 - 0.0013 19.1 0.0 0.0032 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_7 PF12775.7 EGG05240.1 - 0.0051 16.3 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 EGG05240.1 - 0.0057 17.1 0.0 0.037 14.4 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 EGG05240.1 - 0.016 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 EGG05240.1 - 0.028 14.0 0.2 0.092 12.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGG05240.1 - 0.031 14.8 0.0 0.076 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGG05240.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 EGG05240.1 - 0.048 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Methyltr_RsmB-F PF01189.17 EGG05240.1 - 0.05 13.2 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F AAA_3 PF07726.11 EGG05240.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGG05240.1 - 0.083 13.3 0.0 0.32 11.4 0.0 2.0 2 0 0 2 2 1 0 RNA helicase IstB_IS21 PF01695.17 EGG05240.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 EGG05240.1 - 0.096 11.9 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 EGG05240.1 - 0.1 11.9 0.0 0.32 10.3 0.0 1.8 2 0 0 2 2 1 0 KaiC AAA_19 PF13245.6 EGG05240.1 - 0.12 12.7 0.2 0.31 11.4 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGG05240.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGG05240.1 - 0.18 11.8 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IF4E PF01652.18 EGG05241.1 - 1.2e-47 161.7 0.0 1.9e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TFIIA PF03153.13 EGG05242.1 - 0.0022 18.1 7.1 0.0033 17.5 7.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 EGG05242.1 - 0.0036 17.6 8.7 0.0066 16.7 8.7 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Sporozoite_P67 PF05642.11 EGG05242.1 - 0.0046 15.1 10.2 0.011 13.9 10.2 1.6 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DREPP PF05558.12 EGG05242.1 - 0.019 14.9 12.9 0.029 14.3 12.9 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Nop14 PF04147.12 EGG05242.1 - 0.088 11.0 14.8 0.12 10.6 14.8 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2151 PF10221.9 EGG05242.1 - 0.76 8.3 5.0 1.1 7.7 5.0 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.14 EGG05242.1 - 2.1 6.6 11.9 2.8 6.1 11.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 EGG05242.1 - 2.5 7.5 13.4 3.8 6.8 12.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) SAPS PF04499.15 EGG05242.1 - 5 5.8 8.0 7.7 5.2 8.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 EGG05242.1 - 8.7 4.3 18.3 14 3.7 18.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 EGG05242.1 - 8.8 5.4 8.9 15 4.7 8.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 EGG05242.1 - 10 4.8 6.3 19 3.8 6.3 1.4 1 0 0 1 1 1 0 Presenilin HOOK PF05622.12 EGG05244.1 - 0.00093 17.5 25.2 0.0036 15.5 6.4 2.2 1 1 1 2 2 2 2 HOOK protein Chromo PF00385.24 EGG05244.1 - 0.027 14.4 0.5 0.097 12.6 0.5 2.0 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF2203 PF09969.9 EGG05244.1 - 0.045 14.5 0.6 0.045 14.5 0.6 2.8 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DIT1_PvcA PF05141.12 EGG05244.1 - 0.1 12.0 3.9 0.21 11.0 3.9 1.4 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein bZIP_1 PF00170.21 EGG05244.1 - 1.7 8.8 14.1 0.095 12.8 2.6 4.0 3 1 1 4 4 4 0 bZIP transcription factor DUF641 PF04859.12 EGG05244.1 - 2.9 8.2 13.2 0.088 13.1 2.8 2.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Lectin_N PF03954.14 EGG05244.1 - 3.8 7.3 8.1 3.3 7.5 2.0 2.8 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Cnn_1N PF07989.11 EGG05244.1 - 4.4 7.5 16.6 3.9 7.7 0.8 4.0 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Med9 PF07544.13 EGG05244.1 - 5.4 7.2 7.0 0.46 10.6 0.6 2.5 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DAHP_synth_1 PF00793.20 EGG05246.1 - 9.8e-48 162.4 0.1 1.5e-47 161.8 0.1 1.2 1 0 0 1 1 1 1 DAHP synthetase I family E1-E2_ATPase PF00122.20 EGG05248.1 - 0.63 9.5 2.9 1.4 8.4 2.5 1.8 1 1 0 1 1 1 0 E1-E2 ATPase MPS-4 PF17523.2 EGG05248.1 - 8.9 6.5 7.8 5.4 7.2 0.1 3.1 3 0 0 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Pil1 PF13805.6 EGG05249.1 - 5.4e-32 111.3 0.3 7.7e-32 110.8 0.3 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 CENP-F_leu_zip PF10473.9 EGG05249.1 - 0.00078 19.5 3.4 0.0014 18.6 3.4 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 EGG05249.1 - 0.013 15.6 1.9 0.013 15.6 0.6 1.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase RNaseH_pPIWI_RE PF13032.6 EGG05249.1 - 0.027 14.4 0.1 0.05 13.5 0.1 1.4 1 0 0 1 1 1 0 RNaseH domain of pPIWI_RE P2_N PF18628.1 EGG05249.1 - 0.037 13.8 0.1 0.11 12.3 0.1 1.7 2 0 0 2 2 2 0 Viral coat protein P2 N-terminal domain Phage_GP20 PF06810.11 EGG05249.1 - 0.055 13.3 0.6 0.097 12.5 0.6 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 CCDC144C PF14915.6 EGG05249.1 - 0.065 12.3 1.1 0.1 11.7 1.1 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region TMF_TATA_bd PF12325.8 EGG05249.1 - 0.082 13.1 1.9 0.16 12.2 1.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.8 EGG05249.1 - 0.13 12.4 0.6 0.25 11.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) ATG16 PF08614.11 EGG05249.1 - 0.18 12.0 1.2 0.54 10.4 1.2 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 EGG05249.1 - 0.3 10.1 1.6 0.55 9.3 1.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SOGA PF11365.8 EGG05249.1 - 0.65 11.2 3.0 3 9.1 0.6 2.6 1 1 1 2 2 2 0 Protein SOGA Aminotran_5 PF00266.19 EGG05250.1 - 7.4e-33 114.0 0.0 2.1e-32 112.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V zf-RING_2 PF13639.6 EGG05251.1 - 1.7e-09 37.9 3.6 4.9e-09 36.4 3.6 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGG05251.1 - 3.9e-07 29.7 2.6 1.3e-06 28.1 2.6 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGG05251.1 - 1.2e-06 28.5 1.4 2.9e-06 27.2 1.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGG05251.1 - 0.00017 21.8 5.1 0.00066 19.9 5.1 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain FANCL_C PF11793.8 EGG05251.1 - 0.00091 19.4 5.0 0.0015 18.6 3.8 2.1 2 1 0 2 2 2 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EGG05251.1 - 0.0024 17.9 0.4 0.0055 16.7 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EGG05251.1 - 0.0038 17.0 6.8 0.0048 16.7 3.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG05251.1 - 0.0043 16.9 4.0 0.015 15.1 4.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-like PF04071.12 EGG05251.1 - 0.016 15.1 0.5 0.056 13.4 0.5 2.0 1 0 0 1 1 1 0 Cysteine-rich small domain zf-C3HC4_3 PF13920.6 EGG05251.1 - 0.017 15.0 2.8 0.043 13.7 2.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EGG05251.1 - 0.03 14.6 3.4 0.065 13.6 3.4 1.6 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 EGG05251.1 - 0.043 13.9 3.8 0.1 12.8 3.8 1.7 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 EGG05251.1 - 0.075 12.9 3.2 0.17 11.8 3.2 1.7 1 0 0 1 1 1 0 PHD-finger DUF5071 PF16804.5 EGG05251.1 - 0.075 13.3 1.3 0.46 10.8 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5071) zf-3CxxC_2 PF17180.4 EGG05251.1 - 0.085 13.6 5.1 0.22 12.3 0.0 2.8 2 1 0 2 2 2 0 Zinc-binding domain Baculo_RING PF05883.11 EGG05251.1 - 0.087 12.8 0.8 0.29 11.1 0.8 1.9 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.6 EGG05251.1 - 0.36 11.0 2.7 0.97 9.6 2.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EGG05251.1 - 0.5 10.0 8.5 0.024 14.3 2.6 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 EGG05251.1 - 0.87 9.5 4.5 0.37 10.7 1.1 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 EGG05251.1 - 1.2 9.1 3.5 1.1 9.3 0.7 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 EGG05251.1 - 2.4 8.2 5.4 2 8.4 3.3 2.0 2 0 0 2 2 1 0 zinc-RING finger domain SF3A3 PF16837.5 EGG05251.1 - 3.6 8.2 12.9 3.7 8.1 0.2 4.2 3 1 1 4 4 4 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2 PF00096.26 EGG05252.1 - 9e-06 25.9 0.6 0.027 14.9 0.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG05252.1 - 9.6e-05 22.9 1.2 0.24 12.4 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 EGG05252.1 - 0.0058 16.9 1.1 0.85 10.0 0.3 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EGG05252.1 - 0.013 15.8 0.4 0.42 10.9 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HypA PF01155.19 EGG05252.1 - 0.056 13.5 0.4 0.081 13.0 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sgf11 PF08209.11 EGG05252.1 - 0.083 12.5 1.1 0.2 11.3 0.1 1.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) IBR PF01485.21 EGG05253.1 - 9.9e-06 25.7 38.3 0.00041 20.5 9.0 3.9 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain Exo_endo_phos PF03372.23 EGG05254.1 - 2.6e-17 63.2 0.0 4.7e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Snapin_Pallidin PF14712.6 EGG05255.1 - 0.026 14.9 3.6 0.099 13.1 3.6 1.7 1 1 0 1 1 1 0 Snapin/Pallidin Activator-TraM PF11657.8 EGG05255.1 - 0.036 13.9 0.8 0.04 13.8 0.8 1.1 1 0 0 1 1 1 0 Transcriptional activator TraM DUF366 PF04017.12 EGG05255.1 - 0.041 13.4 0.4 0.048 13.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF366) DUF1198 PF06711.11 EGG05255.1 - 0.075 13.1 0.3 0.09 12.8 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) TRAM_LAG1_CLN8 PF03798.16 EGG05256.1 - 3.7e-33 114.9 17.5 4.9e-33 114.5 17.5 1.2 1 0 0 1 1 1 1 TLC domain DUF4234 PF14018.6 EGG05256.1 - 0.29 11.3 3.8 4.7 7.4 1.4 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) TRAM_LAG1_CLN8 PF03798.16 EGG05257.1 - 7.9e-33 113.9 20.4 1.3e-32 113.2 20.4 1.3 1 0 0 1 1 1 1 TLC domain CDP-OH_P_transf PF01066.21 EGG05258.1 - 2.5e-14 53.8 0.0 2.5e-14 53.8 0.0 3.6 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.25 EGG05259.1 - 7e-74 248.5 0.0 9e-74 248.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG05259.1 - 1.8e-37 129.1 0.0 2.3e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG05259.1 - 1.8e-06 27.5 0.0 2.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PACT_coil_coil PF10495.9 EGG05259.1 - 0.0072 16.9 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein YrbL-PhoP_reg PF10707.9 EGG05259.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 EGG05259.1 - 0.029 14.0 0.9 0.55 9.8 0.0 2.5 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGG05259.1 - 0.047 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG05259.1 - 0.09 12.1 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 EGG05261.1 - 7.7e-39 132.5 0.0 9.8e-39 132.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGG05261.1 - 0.026 14.4 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 EGG05261.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Atx10homo_assoc PF09759.9 EGG05262.1 - 0.012 15.6 0.1 0.043 13.8 0.1 2.0 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain ATP11 PF06644.11 EGG05262.1 - 3.5 7.3 7.1 6 6.6 7.1 1.3 1 0 0 1 1 1 0 ATP11 protein Sigma70_ner PF04546.13 EGG05262.1 - 5.2 6.9 10.3 28 4.5 6.5 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF3636 PF12331.8 EGG05262.1 - 7.2 6.4 7.7 5.3 6.9 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3636) adh_short PF00106.25 EGG05263.1 - 1.3e-05 24.8 0.0 0.00012 21.6 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase LcrG PF07216.12 EGG05263.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 LcrG protein adh_short_C2 PF13561.6 EGG05263.1 - 0.19 11.2 0.0 2.7 7.5 0.0 2.2 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Peptidase_M3 PF01432.20 EGG05265.1 - 1.4e-129 433.4 0.0 1.8e-129 433.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 EGG05265.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Effector protein DUF4779 PF16009.5 EGG05266.1 - 2.2 8.3 13.9 0.14 12.2 8.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4779) RRM_1 PF00076.22 EGG05267.1 - 5.7e-05 22.9 0.0 9.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 EGG05267.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding RhoGAP PF00620.27 EGG05270.1 - 0.02 14.7 0.1 0.11 12.3 0.0 2.0 1 1 0 2 2 2 0 RhoGAP domain DUF5356 PF17309.2 EGG05271.1 - 0.25 11.3 0.7 0.33 10.9 0.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5356) Slu7 PF11708.8 EGG05272.1 - 6.8e-95 317.9 23.8 6.8e-95 317.9 23.8 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EGG05272.1 - 0.19 11.5 0.5 0.37 10.5 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4448 PF14610.6 EGG05273.1 - 0.029 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Ribosomal_S17e PF00833.18 EGG05274.1 - 5.6e-62 207.1 0.1 6.5e-62 206.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 AFG1_ATPase PF03969.16 EGG05276.1 - 3.2e-52 177.6 0.0 9.6e-51 172.8 0.0 2.0 2 0 0 2 2 2 1 AFG1-like ATPase AAA_16 PF13191.6 EGG05276.1 - 0.0012 19.3 0.3 0.01 16.2 0.1 2.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 EGG05276.1 - 0.0021 18.4 0.0 2.3 8.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 EGG05276.1 - 0.0032 17.5 0.1 0.044 13.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGG05276.1 - 0.014 15.4 0.0 0.079 13.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGG05276.1 - 0.015 15.6 0.2 0.15 12.4 0.0 2.7 3 2 0 3 3 3 0 AAA domain AAA PF00004.29 EGG05276.1 - 0.022 15.2 0.0 0.1 13.0 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EGG05276.1 - 0.026 14.3 0.0 0.074 12.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 EGG05276.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Evr1_Alr PF04777.13 EGG05277.1 - 1e-28 99.7 2.8 1.1e-28 99.6 0.8 1.8 2 0 0 2 2 2 1 Erv1 / Alr family LolA_2 PF16584.5 EGG05277.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA RabGAP-TBC PF00566.18 EGG05279.1 - 1.1e-33 116.8 0.0 1.4e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Clp1 PF06807.14 EGG05280.1 - 3.2e-28 98.5 0.0 5.3e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 EGG05280.1 - 1.5e-27 95.7 0.0 2.8e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 EGG05280.1 - 1.5e-21 77.0 0.0 1.6e-15 57.4 0.0 2.3 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop PduV-EutP PF10662.9 EGG05280.1 - 0.003 17.3 0.0 0.36 10.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EGG05280.1 - 0.029 14.6 0.4 0.099 12.9 0.2 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGG05280.1 - 0.031 14.3 0.3 0.23 11.5 0.3 2.1 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.23 EGG05280.1 - 0.039 14.1 0.5 0.39 10.8 0.3 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EGG05280.1 - 0.17 12.4 0.2 0.37 11.3 0.2 1.4 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 EGG05280.1 - 0.19 11.5 0.1 1.4 8.7 0.2 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TPR_1 PF00515.28 EGG05281.1 - 3e-09 36.3 2.4 0.00046 19.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG05281.1 - 1.9e-06 27.6 0.4 0.026 14.6 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF2802 PF10975.8 EGG05281.1 - 0.049 13.8 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Symplekin_C PF12295.8 EGG05281.1 - 0.061 13.4 1.8 0.16 12.1 0.4 2.0 1 1 1 2 2 2 0 Symplekin tight junction protein C terminal DUF2309 PF10070.9 EGG05281.1 - 0.076 11.3 0.2 0.14 10.5 0.1 1.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2309) TPR_12 PF13424.6 EGG05281.1 - 0.098 13.0 0.7 6.5 7.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat BLOC1_2 PF10046.9 EGG05281.1 - 0.26 11.6 2.5 3.8 7.9 0.1 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF501 PF04417.12 EGG05281.1 - 0.3 10.9 1.7 0.75 9.6 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF501) MIT PF04212.18 EGG05281.1 - 1.9 8.6 6.2 0.76 9.9 1.2 2.8 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Arrestin_C PF02752.22 EGG05282.1 - 4.8e-06 27.1 0.0 0.006 17.0 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGG05282.1 - 0.00058 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain TPR_2 PF07719.17 EGG05283.1 - 2.2e-25 86.6 13.2 0.0021 18.0 0.6 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG05283.1 - 2.3e-24 85.4 10.3 1.3e-10 41.3 0.0 7.0 6 1 1 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EGG05283.1 - 6.2e-17 60.6 6.9 0.0046 16.7 0.5 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGG05283.1 - 3.2e-16 59.4 12.3 1.1e-06 28.8 0.1 7.3 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG05283.1 - 1.9e-12 46.4 5.6 0.0093 16.1 0.2 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG05283.1 - 1.9e-09 37.9 3.7 0.63 10.6 0.0 6.4 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGG05283.1 - 1.2e-07 31.6 0.9 36 5.1 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG05283.1 - 1.4e-07 31.7 15.3 0.34 11.8 0.0 9.2 7 3 2 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG05283.1 - 1.1e-06 28.9 15.3 5.7 7.8 0.6 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG05283.1 - 2e-06 28.3 18.8 0.042 14.5 2.1 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG05283.1 - 5.1e-06 26.1 9.2 3.2 8.0 0.0 7.2 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG05283.1 - 5.5e-05 22.8 8.9 0.47 10.2 0.1 6.0 6 1 1 7 7 7 2 TPR repeat TPR_10 PF13374.6 EGG05283.1 - 0.00033 20.4 9.0 1.5 8.8 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGG05283.1 - 0.028 14.5 0.3 0.028 14.5 0.3 5.0 7 0 0 7 7 5 0 Tetratricopeptide repeat aGPT-Pplase2 PF18724.1 EGG05283.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 BTAD PF03704.17 EGG05283.1 - 0.24 11.8 1.6 2 8.8 1.0 2.5 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 EGG05283.1 - 1.1 10.1 7.0 42 5.2 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat FliP PF00813.20 EGG05284.1 - 0.0079 16.1 0.6 0.015 15.2 0.6 1.4 1 0 0 1 1 1 1 FliP family Helitron_like_N PF14214.6 EGG05287.1 - 0.00079 19.7 0.2 0.0011 19.3 0.2 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus F-box-like PF12937.7 EGG05289.1 - 1.1 9.2 3.8 0.79 9.7 0.9 2.3 2 1 0 2 2 2 0 F-box-like DUF3195 PF11424.8 EGG05292.1 - 0.1 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGG05292.1 - 0.15 11.0 0.4 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 NUC194 domain DUF2170 PF09938.9 EGG05292.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) NUP50 PF08911.11 EGG05296.1 - 0.88 10.3 5.2 5.1 7.8 0.3 3.2 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) TRAPP PF04051.16 EGG05297.1 - 3.6e-40 137.0 0.0 4.3e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component RHS_repeat PF05593.14 EGG05298.1 - 0.012 16.1 0.1 0.036 14.6 0.1 1.9 1 0 0 1 1 1 0 RHS Repeat DNA_primase_S PF01896.19 EGG05300.1 - 9.4e-16 58.4 0.0 1.7e-15 57.6 0.0 1.4 1 1 0 1 1 1 1 DNA primase small subunit GNAT_acetyltran PF12746.7 EGG05300.1 - 0.02 14.4 3.2 1.7 8.1 0.3 2.1 1 1 1 2 2 2 0 GNAT acetyltransferase PRESAN PF09687.10 EGG05300.1 - 0.035 14.7 1.2 0.069 13.7 1.0 1.5 1 1 0 1 1 1 0 Plasmodium RESA N-terminal GPI-anchored PF10342.9 EGG05302.1 - 2.1e-12 47.6 1.8 2.1e-12 47.6 1.8 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4141 PF13605.6 EGG05302.1 - 0.075 12.3 1.9 0.55 9.5 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4141) Diacid_rec PF05651.13 EGG05302.1 - 0.1 12.3 0.2 0.2 11.3 0.1 1.6 2 0 0 2 2 2 0 Putative sugar diacid recognition KDZ PF18758.1 EGG05304.1 - 7.8e-48 163.0 0.1 1.5e-47 162.1 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGG05304.1 - 1.7e-22 79.5 1.3 3.1e-22 78.7 1.3 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG05304.1 - 4.5e-08 33.2 0.4 9.3e-08 32.2 0.4 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases zf-UDP PF14569.6 EGG05305.1 - 0.049 13.8 0.5 0.13 12.4 0.5 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF951 PF06107.11 EGG05305.1 - 0.07 13.0 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) ABC_tran_CTD PF16326.5 EGG05306.1 - 0.0022 18.2 3.4 0.0088 16.3 0.0 2.3 1 1 1 2 2 2 1 ABC transporter C-terminal domain Peptidase_S46 PF10459.9 EGG05306.1 - 0.082 11.5 1.0 0.097 11.3 1.0 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF1515 PF07439.11 EGG05306.1 - 0.11 12.6 1.3 0.12 12.4 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) APG6_N PF17675.1 EGG05306.1 - 1.7 9.2 7.2 1.2 9.7 5.1 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region CxC1 PF18802.1 EGG05307.1 - 4.6e-27 94.2 0.4 6.9e-27 93.6 0.4 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG05307.1 - 2.8e-06 27.5 0.1 4.6e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases PRIMA1 PF16101.5 EGG05307.1 - 1.2 9.2 4.8 7.3 6.7 1.9 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CxC5 PF18718.1 EGG05310.1 - 3e-21 75.7 6.0 5.2e-21 74.9 6.0 1.4 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG05310.1 - 0.00023 21.4 0.6 0.0019 18.4 0.0 2.4 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases Sigma70_ner PF04546.13 EGG05312.1 - 0.097 12.5 8.3 0.19 11.6 8.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 EGG05312.1 - 0.21 9.6 11.0 0.34 9.0 11.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 EGG05312.1 - 2.7 7.7 18.1 0.06 13.1 7.6 2.9 2 1 0 2 2 2 0 Pox virus Ag35 surface protein NOA36 PF06524.12 EGG05312.1 - 4.8 6.4 16.9 1.4 8.2 13.3 1.9 2 0 0 2 2 2 0 NOA36 protein TT_ORF2 PF02957.15 EGG05312.1 - 4.9 8.1 11.9 1.8 9.5 7.6 2.5 2 0 0 2 2 2 0 TT viral ORF2 DUF4746 PF15928.5 EGG05312.1 - 5.5 6.3 11.4 15 4.9 11.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FAM176 PF14851.6 EGG05312.1 - 9 6.0 12.2 0.35 10.5 5.6 2.1 2 0 0 2 2 2 0 FAM176 family Beta_helix PF13229.6 EGG05313.1 - 6e-07 29.4 0.0 2.3e-05 24.3 0.1 2.5 1 1 1 2 2 2 2 Right handed beta helix region B_lectin PF01453.24 EGG05313.1 - 1.7e-05 25.3 0.0 0.0027 18.2 0.1 2.9 2 1 1 3 3 3 1 D-mannose binding lectin DUF2418 PF10332.9 EGG05316.1 - 6.1e-28 97.2 1.4 9.9e-28 96.5 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF936 PF06075.12 EGG05316.1 - 0.15 10.9 7.5 0.21 10.5 7.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF2913 PF11140.8 EGG05317.1 - 0.024 14.4 0.4 7.7 6.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2913) Cyclin_N PF00134.23 EGG05318.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain HSF_DNA-bind PF00447.17 EGG05319.1 - 1.8e-30 105.4 6.7 7.7e-30 103.4 6.7 2.1 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 EGG05319.1 - 4.6e-24 84.7 0.1 1.3e-23 83.3 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain DUF1664 PF07889.12 EGG05319.1 - 0.079 13.0 0.9 0.17 11.9 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Lipoprotein_17 PF04200.12 EGG05319.1 - 5.4 7.4 9.2 21 5.5 1.0 3.2 2 0 0 2 2 2 0 Lipoprotein associated domain MBOAT_2 PF13813.6 EGG05320.1 - 3.5e-08 33.6 8.7 3.5e-08 33.6 8.7 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family SRP40_C PF05022.12 EGG05321.1 - 2.4e-29 102.0 1.2 2.4e-29 102.0 1.2 1.9 2 0 0 2 2 2 1 SRP40, C-terminal domain WD40 PF00400.32 EGG05322.1 - 2.2e-42 142.2 15.7 3.1e-06 27.8 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EGG05322.1 - 2.8e-09 36.7 0.2 5.7e-09 35.7 0.2 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EGG05322.1 - 1.8e-07 31.4 2.8 9.9 6.5 0.0 6.4 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 EGG05322.1 - 2.2e-07 30.6 0.4 4.6e-07 29.5 0.1 1.7 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 EGG05322.1 - 0.0019 16.9 12.7 1.4 7.5 0.2 5.5 5 1 2 7 7 7 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EGG05322.1 - 0.002 17.8 2.9 1.1 8.8 0.1 3.0 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 EGG05322.1 - 0.0089 15.9 5.6 0.93 9.5 0.0 5.0 5 0 0 5 5 5 1 PQQ enzyme repeat PQQ_3 PF13570.6 EGG05322.1 - 0.53 10.8 9.2 4.4 7.9 0.6 4.8 4 1 0 4 4 4 0 PQQ-like domain UPF0029 PF01205.19 EGG05323.1 - 4.9e-33 113.6 0.1 9.6e-33 112.7 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EGG05323.1 - 4e-07 30.3 2.9 9.4e-07 29.1 2.4 1.9 2 0 0 2 2 2 1 RWD domain UQ_con PF00179.26 EGG05323.1 - 0.018 14.7 0.1 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme RIC1 PF07064.13 EGG05324.1 - 1.5e-45 155.6 0.0 2.7e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 RIC1 Kelch_6 PF13964.6 EGG05324.1 - 0.0083 16.4 0.1 3.6 8.0 0.0 3.5 3 0 0 3 3 3 2 Kelch motif ANAPC4_WD40 PF12894.7 EGG05324.1 - 0.045 14.1 0.3 1.6 9.1 0.0 3.5 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Got1 PF04178.12 EGG05325.1 - 5.4e-32 110.6 18.3 5.4e-32 110.6 18.3 1.4 2 0 0 2 2 2 1 Got1/Sft2-like family DUF2070 PF09843.9 EGG05325.1 - 0.054 11.8 9.6 0.061 11.6 9.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) EcsB PF05975.12 EGG05325.1 - 1.2 7.9 13.5 0.82 8.5 12.1 1.3 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB PUFD PF16553.5 EGG05326.1 - 0.015 15.4 0.1 0.035 14.2 0.1 1.5 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain PP_M1 PF03012.14 EGG05326.1 - 0.26 10.8 3.7 0.38 10.3 3.7 1.2 1 0 0 1 1 1 0 Phosphoprotein TT_ORF2 PF02957.15 EGG05326.1 - 0.29 12.0 6.9 0.82 10.6 6.9 1.7 1 0 0 1 1 1 0 TT viral ORF2 HEM4 PF02602.15 EGG05327.1 - 3e-11 43.1 0.0 9.4e-09 35.0 0.0 2.1 2 0 0 2 2 2 2 Uroporphyrinogen-III synthase HemD Sod_Fe_C PF02777.18 EGG05330.1 - 8e-31 106.2 0.4 1.4e-30 105.5 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGG05330.1 - 2.9e-28 98.2 1.6 3e-28 98.1 0.2 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 EGG05331.1 - 1.2e-28 99.2 0.0 2e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGG05331.1 - 3.7e-28 97.8 0.7 7.6e-28 96.8 0.7 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Abhydrolase_1 PF00561.20 EGG05333.1 - 0.0065 16.1 0.0 0.015 15.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EGG05333.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_2 PF01674.18 EGG05333.1 - 0.016 14.7 0.0 0.28 10.7 0.0 2.0 1 1 0 1 1 1 0 Lipase (class 2) DUF2974 PF11187.8 EGG05333.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF915 PF06028.11 EGG05333.1 - 0.048 13.0 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 EGG05333.1 - 0.097 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase BAAT_C PF08840.11 EGG05333.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal 2OG-FeII_Oxy_2 PF13532.6 EGG05334.1 - 1.3e-10 41.8 0.0 2.3e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DAHP_synth_1 PF00793.20 EGG05338.1 - 3.5e-89 298.3 0.0 4.7e-88 294.6 0.0 1.9 1 1 0 1 1 1 1 DAHP synthetase I family COesterase PF00135.28 EGG05339.1 - 1.5e-10 40.6 0.2 5.8e-10 38.7 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG05339.1 - 1.9e-10 41.0 0.0 2.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG05339.1 - 5.8e-06 27.1 0.3 1.1e-05 26.2 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGG05339.1 - 0.0034 16.9 0.1 0.044 13.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_C14 PF00656.22 EGG05339.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Caspase domain Methyltransf_11 PF08241.12 EGG05340.1 - 1.5e-18 67.2 0.0 2.5e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG05340.1 - 1.9e-17 63.8 0.0 3.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG05340.1 - 8e-14 51.7 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG05340.1 - 8.3e-11 42.5 0.0 1.3e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG05340.1 - 2.6e-07 30.6 0.0 6.2e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG05340.1 - 7.5e-07 28.7 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGG05340.1 - 1.2e-05 24.9 0.0 2.8e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGG05340.1 - 2.6e-05 23.8 0.0 3.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EGG05340.1 - 0.0047 16.7 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EGG05340.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.18 EGG05340.1 - 0.044 13.5 0.0 2.6 7.7 0.0 2.1 2 0 0 2 2 2 0 DNA methylase ADH_zinc_N PF00107.26 EGG05340.1 - 0.064 13.2 0.0 0.21 11.6 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_PK PF05891.12 EGG05340.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Glyco_hydro_26 PF02156.15 EGG05341.1 - 0.00092 18.7 2.1 0.00092 18.7 2.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 26 tRNA_anti-like PF12869.7 EGG05341.1 - 0.032 13.9 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 tRNA_anti-like FAD-oxidase_C PF02913.19 EGG05342.1 - 1.2e-56 192.1 0.0 1.6e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGG05342.1 - 2e-22 79.4 0.0 4.6e-19 68.6 0.0 2.4 1 1 1 2 2 2 2 FAD binding domain Amidohydro_3 PF07969.11 EGG05343.1 - 3.3e-66 224.7 0.0 4e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EGG05343.1 - 3e-06 26.8 0.0 0.0013 18.2 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family SRI PF08236.11 EGG05344.1 - 2.5e-18 66.0 3.2 7.6e-18 64.5 3.2 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EGG05344.1 - 1.3e-14 54.9 0.0 1.3e-14 54.9 0.0 3.1 2 2 0 2 2 2 1 SET domain AWS PF17907.1 EGG05344.1 - 1.9e-11 43.8 8.8 1.9e-11 43.8 8.8 2.2 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 EGG05344.1 - 2.2e-07 30.8 2.5 1.1e-06 28.5 0.6 2.7 2 0 0 2 2 2 1 TFIIS helical bundle-like domain WW PF00397.26 EGG05344.1 - 4.6e-06 26.6 0.7 9.2e-06 25.6 0.7 1.6 1 0 0 1 1 1 1 WW domain DUF4704 PF15787.5 EGG05344.1 - 0.0025 17.1 0.6 0.0044 16.3 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) Rubis-subs-bind PF09273.11 EGG05344.1 - 0.072 13.8 2.0 0.39 11.4 1.9 2.3 1 1 0 1 1 1 0 Rubisco LSMT substrate-binding LapA_dom PF06305.11 EGG05345.1 - 0.047 13.5 0.9 0.065 13.1 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 EGG05345.1 - 0.099 13.5 0.1 0.28 12.1 0.1 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Nop14 PF04147.12 EGG05346.1 - 0.09 11.0 22.3 0.14 10.3 22.3 1.2 1 0 0 1 1 1 0 Nop14-like family Smg8_Smg9 PF10220.9 EGG05346.1 - 0.87 7.8 18.0 0.013 13.9 11.0 1.4 2 0 0 2 2 2 0 Smg8_Smg9 Macoilin PF09726.9 EGG05346.1 - 8.4 4.8 15.8 9.8 4.6 15.8 1.2 1 0 0 1 1 1 0 Macoilin family AMP-binding PF00501.28 EGG05347.1 - 8.2e-72 242.1 0.0 1.1e-71 241.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG05347.1 - 0.00026 21.9 0.1 0.00084 20.3 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Thioredoxin PF00085.20 EGG05348.1 - 3.2e-58 194.1 1.6 7.5e-28 96.6 0.0 3.6 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 EGG05348.1 - 1.2e-37 129.6 6.7 3.2e-30 105.4 3.4 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGG05348.1 - 4.1e-07 30.1 0.1 0.0093 16.1 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.17 EGG05348.1 - 1.1e-06 28.0 1.5 1.5e-06 27.5 0.4 1.7 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_2 PF13098.6 EGG05348.1 - 2.7e-06 27.8 1.9 0.036 14.5 0.2 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGG05348.1 - 5.9e-05 23.3 4.0 0.26 11.6 0.0 5.2 5 2 1 6 6 6 2 Thioredoxin-like Thioredoxin_4 PF13462.6 EGG05348.1 - 0.00043 20.5 2.0 0.66 10.1 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin AhpC-TSA PF00578.21 EGG05348.1 - 0.00047 20.1 0.1 1.6 8.7 0.0 3.5 3 0 0 3 3 3 2 AhpC/TSA family OST3_OST6 PF04756.13 EGG05348.1 - 0.0011 18.4 0.8 0.0063 15.9 0.0 2.5 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EGG05348.1 - 0.076 12.7 0.2 2.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Redoxin Miff PF05644.11 EGG05349.1 - 0.24 11.0 3.6 0.6 9.7 3.6 1.6 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DHHC PF01529.20 EGG05350.1 - 1.8e-32 112.3 9.7 1.8e-32 112.3 9.7 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 EGG05350.1 - 4.5e-31 107.3 4.4 1.2e-13 51.5 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EGG05350.1 - 1.6e-26 91.5 9.5 2.8e-07 30.7 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 EGG05350.1 - 5.3e-26 90.6 4.0 8e-09 35.9 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG05350.1 - 2.7e-22 76.4 1.5 0.00014 22.0 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EGG05350.1 - 7.2e-22 77.2 2.1 8.1e-07 29.2 0.1 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) RWD PF05773.22 EGG05351.1 - 6.3e-11 42.6 0.5 1.4e-10 41.5 0.1 1.7 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 EGG05351.1 - 4.7e-06 27.0 8.6 6.7e-06 26.5 6.9 2.0 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 Polysacc_lyase PF14099.6 EGG05352.1 - 0.00039 20.3 0.0 0.00062 19.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase SH3_9 PF14604.6 EGG05353.1 - 9e-06 25.5 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Zip PF02535.22 EGG05353.1 - 0.44 9.7 8.9 0.75 9.0 8.9 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter UQ_con PF00179.26 EGG05354.1 - 4.2e-38 130.2 0.0 5.2e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MBOAT_2 PF13813.6 EGG05355.1 - 1.5e-11 44.3 3.7 2.9e-11 43.5 3.7 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CTP_transf_like PF01467.26 EGG05357.1 - 3.8e-25 88.7 0.0 4.9e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like FGE-sulfatase PF03781.16 EGG05357.1 - 0.052 13.1 0.2 0.071 12.7 0.2 1.1 1 0 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 TBP PF00352.21 EGG05358.1 - 3.9e-68 225.4 0.2 8e-33 112.3 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EGG05358.1 - 1.6e-05 24.9 0.0 0.21 11.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Peptidase_M10 PF00413.24 EGG05360.1 - 0.02 14.7 0.4 0.031 14.1 0.4 1.5 1 1 0 1 1 1 0 Matrixin Epimerase PF01370.21 EGG05360.1 - 0.057 12.9 0.1 0.083 12.3 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family SUa-2TM PF18179.1 EGG05360.1 - 0.16 11.3 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain Pro_CA PF00484.19 EGG05361.1 - 5.5e-45 153.5 1.2 6.3e-45 153.2 1.2 1.0 1 0 0 1 1 1 1 Carbonic anhydrase VirB8 PF04335.13 EGG05361.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 VirB8 protein EF-1_beta_acid PF10587.9 EGG05363.1 - 0.37 11.3 5.6 1.1 9.8 5.6 1.8 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region FMN_bind_2 PF04299.12 EGG05364.1 - 0.0052 16.5 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Putative FMN-binding domain FSAP_sig_propep PF03032.15 EGG05364.1 - 0.22 11.6 2.2 0.88 9.7 0.5 2.4 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide DUF1179 PF06678.11 EGG05368.1 - 0.11 12.6 0.3 0.24 11.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Trypsin PF00089.26 EGG05368.1 - 0.19 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Trypsin SpoVIF PF14069.6 EGG05369.1 - 0.17 11.6 1.4 7 6.5 0.3 2.4 1 1 1 2 2 2 0 Stage VI sporulation protein F PEP_mutase PF13714.6 EGG05369.1 - 0.21 11.0 0.0 0.37 10.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Kinesin PF00225.23 EGG05370.1 - 9.2e-100 333.8 3.1 4.4e-99 331.6 3.1 2.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGG05370.1 - 5.3e-21 75.1 1.4 2.7e-20 72.8 0.1 2.9 2 2 0 2 2 2 1 Microtubule binding Vps36-NZF-N PF16988.5 EGG05373.1 - 0.04 13.3 0.2 0.15 11.5 0.2 2.0 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF2458 PF10454.9 EGG05374.1 - 1.4e-06 28.0 0.9 3e-06 27.0 0.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2458) DGCR6 PF07324.11 EGG05374.1 - 4.5e-06 26.4 5.8 5.1e-05 23.0 5.8 2.0 1 1 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein Cohesin_HEAT PF12765.7 EGG05374.1 - 0.055 13.8 0.1 0.17 12.2 0.1 1.9 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion WW PF00397.26 EGG05375.1 - 3.3e-05 23.9 5.9 3.3e-05 23.9 5.9 2.3 2 0 0 2 2 2 1 WW domain Tcp10_C PF07202.13 EGG05375.1 - 0.0024 17.9 0.6 0.0024 17.9 0.6 2.2 1 1 1 2 2 2 1 T-complex protein 10 C-terminus SDA1 PF05285.12 EGG05375.1 - 0.045 13.2 27.8 0.055 12.9 27.8 1.1 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.11 EGG05375.1 - 7.3 4.5 19.7 12 3.8 19.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Kelch_2 PF07646.15 EGG05376.1 - 0.14 12.1 1.1 20 5.4 0.0 2.5 2 0 0 2 2 2 0 Kelch motif Alpha_kinase PF02816.18 EGG05377.1 - 1e-06 29.0 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family Alpha_kinase PF02816.18 EGG05378.1 - 1.1e-08 35.4 0.0 1.7e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Med13_C PF06333.12 EGG05378.1 - 0.078 12.2 0.7 0.14 11.4 0.7 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DUF3450 PF11932.8 EGG05378.1 - 0.14 11.5 0.0 0.39 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DEAD PF00270.29 EGG05379.1 - 1.8e-26 93.0 0.0 3.3e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG05379.1 - 3.6e-12 46.6 0.2 2.7e-11 43.8 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.11 EGG05379.1 - 1.4e-07 32.0 0.1 3.7e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 EGG05379.1 - 8.1e-05 22.7 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_S16 PF00886.19 EGG05380.1 - 1.3e-21 76.4 0.0 2.3e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 CDI PF02234.19 EGG05381.1 - 0.1 12.8 1.7 0.25 11.6 1.7 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Retrotran_gag_2 PF14223.6 EGG05383.1 - 7.2e-09 35.4 0.8 2.1e-08 33.9 0.4 1.9 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type DUF349 PF03993.12 EGG05383.1 - 0.21 11.9 0.7 21 5.5 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) C2 PF00168.30 EGG05384.1 - 1.7e-85 282.0 1.1 1.4e-20 73.4 0.0 6.2 6 0 0 6 6 6 5 C2 domain NT-C2 PF10358.9 EGG05384.1 - 0.042 13.6 0.0 5 6.8 0.0 3.2 3 0 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins Peptidase_S80 PF07230.11 EGG05385.1 - 0.0078 14.6 0.6 0.012 13.9 0.6 1.2 1 0 0 1 1 1 1 Bacteriophage T4-like capsid assembly protein (Gp20) R3H-assoc PF13902.6 EGG05385.1 - 2.2 8.7 5.4 0.67 10.3 0.4 2.3 2 1 0 2 2 2 0 R3H-associated N-terminal domain Mg_trans_NIPA PF05653.14 EGG05386.1 - 1.6e-64 217.9 19.3 1.6e-62 211.3 15.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EGG05386.1 - 0.00016 21.9 4.0 0.00016 21.9 4.0 4.5 4 1 0 4 4 4 1 EamA-like transporter family TssN PF17555.2 EGG05386.1 - 1.3 8.3 14.8 2.5 7.4 14.8 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF373 PF04123.13 EGG05386.1 - 3.5 7.0 17.3 0.82 9.0 13.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Sod_Cu PF00080.20 EGG05387.1 - 8.2e-15 55.2 0.0 1.1e-14 54.8 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pkinase PF00069.25 EGG05391.1 - 1.2e-62 211.7 0.0 2.1e-62 210.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG05391.1 - 6.5e-35 120.6 0.0 1.1e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG05391.1 - 6.8e-06 25.3 3.7 1.3e-05 24.3 3.7 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGG05391.1 - 1.1e-05 25.0 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG05391.1 - 0.0017 17.7 0.3 0.004 16.5 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_3 PF14593.6 EGG05391.1 - 0.0021 18.1 4.4 0.22 11.6 0.1 2.9 2 1 0 2 2 2 2 PH domain APH PF01636.23 EGG05391.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGG05391.1 - 0.065 12.8 4.6 0.069 12.8 0.0 2.6 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pex14_N PF04695.13 EGG05391.1 - 1.5 9.4 9.3 2.2 9.0 7.9 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFA2_Winged_2 PF18121.1 EGG05394.1 - 9.5e-18 63.7 0.0 2.3e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EGG05394.1 - 7e-05 23.0 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain YcgR PF07317.12 EGG05394.1 - 0.026 14.4 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Flagellar regulator YcgR TraB PF01963.17 EGG05396.1 - 0.021 14.8 0.8 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 TraB family Sigma54_DBD PF04552.13 EGG05396.1 - 0.079 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Sigma-54, DNA binding domain Retrotran_gag_2 PF14223.6 EGG05400.1 - 0.00012 21.8 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 EGG05400.1 - 0.34 11.1 4.9 0.11 12.6 1.9 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 EGG05400.1 - 0.37 10.7 3.2 0.66 9.8 3.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Complex1_LYR PF05347.15 EGG05401.1 - 1.2e-06 28.4 0.1 2e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGG05401.1 - 0.00042 21.0 0.1 0.00072 20.3 0.1 1.5 1 1 0 1 1 1 1 Complex1_LYR-like MBOAT_2 PF13813.6 EGG05402.1 - 1.8e-15 57.0 4.8 4.2e-15 55.8 4.8 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF4022 PF13214.6 EGG05402.1 - 0.056 13.7 0.1 0.16 12.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4022) Parathyroid PF01279.17 EGG05405.1 - 0.095 13.3 2.7 3.6 8.2 0.5 3.3 2 2 1 3 3 3 0 Parathyroid hormone family Ribosom_S12_S23 PF00164.25 EGG05406.1 - 3.2e-34 116.9 1.7 4.2e-34 116.6 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 adh_short PF00106.25 EGG05407.1 - 1.2e-29 103.2 0.1 1.5e-29 102.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG05407.1 - 3.9e-28 98.6 0.0 6.1e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG05407.1 - 8.7e-08 32.3 0.6 2.2e-07 31.0 0.2 1.8 2 0 0 2 2 2 1 KR domain ApbA PF02558.16 EGG05407.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF16 PF01519.16 EGG05407.1 - 0.0063 17.0 0.6 0.017 15.6 0.6 1.6 1 1 0 1 1 1 1 Protein of unknown function DUF16 DFP PF04127.15 EGG05407.1 - 0.088 12.6 1.3 0.27 11.0 1.3 1.9 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 EGG05407.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peroxidase_2 PF01328.17 EGG05409.1 - 1.1e-26 94.5 0.0 1.5e-26 94.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 EGG05410.1 - 2.2e-37 129.4 0.0 2.9e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF89 PF01937.19 EGG05411.1 - 1.4e-100 336.7 1.6 1.6e-100 336.5 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF287 PF03384.14 EGG05411.1 - 0.32 11.4 3.1 4.1 7.9 0.6 2.5 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 zf-RING_11 PF17123.5 EGG05415.1 - 3.6e-08 33.0 2.7 3.6e-08 33.0 2.7 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 EGG05415.1 - 5e-08 33.1 9.3 1.7e-07 31.5 9.3 2.0 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 EGG05415.1 - 4.1e-05 23.5 0.0 0.00011 22.2 0.0 1.7 1 1 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 EGG05415.1 - 0.0056 16.6 7.2 0.0098 15.8 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGG05415.1 - 0.13 12.1 5.0 1.6 8.6 5.0 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGG05415.1 - 0.13 12.3 7.9 0.11 12.5 3.5 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGG05415.1 - 0.18 11.7 8.5 1.3 8.9 8.5 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG05415.1 - 0.19 11.6 9.1 0.66 9.9 9.1 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG05415.1 - 0.65 9.9 8.5 1.6 8.6 8.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Grg1 PF11034.8 EGG05416.1 - 1.8e-27 95.3 14.4 2.1e-27 95.2 14.4 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Phe_tRNA-synt_N PF02912.18 EGG05416.1 - 0.011 15.6 1.2 0.029 14.3 1.2 1.8 1 1 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Borrelia_P83 PF05262.11 EGG05417.1 - 1 7.8 21.4 1.4 7.3 21.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Grg1 PF11034.8 EGG05418.1 - 1.5e-26 92.4 13.6 1.8e-26 92.2 13.6 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 DSPc PF00782.20 EGG05420.1 - 2.8e-16 59.6 0.2 2.8e-16 59.5 0.2 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGG05420.1 - 0.011 16.0 0.0 0.011 16.0 0.0 1.1 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EGG05420.1 - 0.02 14.5 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ldh_1_N PF00056.23 EGG05421.1 - 1.4e-46 158.1 0.2 2e-46 157.6 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EGG05421.1 - 9.4e-45 152.5 0.0 1.3e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Semialdhyde_dh PF01118.24 EGG05421.1 - 0.00024 21.5 0.1 0.0018 18.7 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EGG05421.1 - 0.0017 17.5 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGG05421.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 EGG05421.1 - 0.038 13.3 0.0 0.21 10.9 0.0 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.16 EGG05421.1 - 0.059 12.9 0.1 1.1 8.7 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase NmrA PF05368.13 EGG05421.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 EGG05421.1 - 0.12 12.6 0.1 0.46 10.7 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PP28 PF10252.9 EGG05422.1 - 3.4e-25 88.3 13.9 3.4e-25 88.3 13.9 2.8 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 RVT_3 PF13456.6 EGG05424.1 - 6.4e-05 22.8 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like OSCP PF00213.18 EGG05425.1 - 0.059 13.5 0.4 0.097 12.8 0.4 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit TrkH PF02386.16 EGG05425.1 - 0.093 11.2 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Cation transport protein Adaptin_N PF01602.20 EGG05426.1 - 3.6e-133 444.9 4.8 4.4e-133 444.6 4.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGG05426.1 - 1.2e-58 197.7 4.5 1.9e-56 190.6 0.3 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGG05426.1 - 7.4e-16 58.3 7.4 2.2e-07 31.2 0.2 6.2 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.22 EGG05426.1 - 3.5e-08 33.0 7.5 0.021 15.0 0.0 7.5 8 0 0 8 8 8 2 HEAT repeat Cnd3 PF12719.7 EGG05426.1 - 3e-05 23.4 2.3 0.00049 19.4 0.2 3.0 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 EGG05426.1 - 6.1e-05 22.9 1.7 1.8 8.7 0.0 5.6 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EGG05426.1 - 0.00051 19.7 0.1 1.5 8.4 0.0 3.2 2 1 1 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 EGG05426.1 - 0.0014 18.8 2.5 9.5 6.4 0.0 5.0 3 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGG05426.1 - 0.0026 18.2 4.4 1.3 9.6 0.0 6.5 7 2 2 9 9 9 1 HEAT-like repeat Sec7_N PF12783.7 EGG05426.1 - 0.034 14.0 0.8 0.23 11.4 0.1 2.4 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal WD40 PF00400.32 EGG05427.1 - 1.6e-07 31.9 1.1 0.00039 21.2 0.0 5.1 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG05427.1 - 0.00044 20.5 0.0 4 7.8 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Elf1 PF05129.13 EGG05428.1 - 0.047 13.7 0.9 0.22 11.6 0.9 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Sec20 PF03908.13 EGG05428.1 - 0.054 13.4 2.3 0.96 9.4 0.5 2.6 2 0 0 2 2 2 0 Sec20 CNH PF00780.22 EGG05431.1 - 3.9e-11 43.1 0.0 7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 EGG05431.1 - 1e-05 25.7 0.6 1e-05 25.7 0.6 3.5 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EGG05431.1 - 0.0095 16.4 3.1 0.014 15.9 0.1 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Ada3 PF10198.9 EGG05431.1 - 0.096 12.8 0.1 0.27 11.4 0.1 1.7 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 Adap_comp_sub PF00928.21 EGG05432.1 - 2.6e-18 66.3 0.0 3.8e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 EGG05432.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Clat_adaptor_s PF01217.20 EGG05432.1 - 0.025 14.5 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain DGOK PF05035.12 EGG05432.1 - 0.029 13.3 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase AAA PF00004.29 EGG05433.1 - 7e-56 188.3 0.0 9.2e-45 152.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG05433.1 - 7.5e-08 32.9 0.5 0.04 14.3 0.1 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 EGG05433.1 - 3.8e-07 30.2 0.0 0.58 10.2 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EGG05433.1 - 1.1e-06 28.8 0.1 0.0047 16.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGG05433.1 - 1.5e-06 28.1 0.1 0.00026 20.8 0.0 2.8 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EGG05433.1 - 3e-05 24.0 0.1 0.12 12.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 EGG05433.1 - 0.00035 20.7 0.0 0.0097 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGG05433.1 - 0.00039 20.7 1.4 0.054 13.8 0.1 3.6 2 2 1 3 3 3 1 AAA domain TIP49 PF06068.13 EGG05433.1 - 0.00039 19.7 0.2 0.0027 17.0 0.1 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 EGG05433.1 - 0.00043 20.8 0.4 0.028 15.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 EGG05433.1 - 0.00059 19.6 0.0 1.3 8.7 0.0 2.9 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 EGG05433.1 - 0.0015 18.2 0.1 0.27 10.8 0.1 2.8 2 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EGG05433.1 - 0.0017 17.9 0.0 0.026 14.0 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGG05433.1 - 0.0021 17.8 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EGG05433.1 - 0.0022 18.4 0.0 0.16 12.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_3 PF07726.11 EGG05433.1 - 0.0053 16.6 0.0 0.085 12.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EGG05433.1 - 0.0087 15.4 0.1 0.028 13.8 0.1 1.8 2 0 0 2 2 2 1 KaiC AAA_lid_3 PF17862.1 EGG05433.1 - 0.0096 15.7 0.0 0.84 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain DUF815 PF05673.13 EGG05433.1 - 0.014 14.6 0.1 1.6 7.8 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EGG05433.1 - 0.015 14.7 0.4 0.043 13.2 0.2 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.6 EGG05433.1 - 0.022 14.9 0.0 0.54 10.4 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_33 PF13671.6 EGG05433.1 - 0.032 14.4 0.0 0.4 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EGG05433.1 - 0.032 13.3 0.0 0.07 12.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Vps4_C PF09336.10 EGG05433.1 - 0.034 14.1 0.0 0.33 11.0 0.0 2.6 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain PhoH PF02562.16 EGG05433.1 - 0.04 13.4 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 EGG05433.1 - 0.05 12.9 0.1 10 5.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 EGG05433.1 - 0.11 12.4 0.0 0.83 9.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 EGG05433.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGG05433.1 - 0.23 11.4 1.6 26 4.7 0.1 3.2 3 1 1 4 4 4 0 NACHT domain AAA_11 PF13086.6 EGG05433.1 - 0.48 10.2 1.5 1.2 8.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain Na_Ca_ex PF01699.24 EGG05435.1 - 2.4e-42 144.5 32.0 2.3e-23 82.9 15.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Ribonuc_red_2_N PF08471.10 EGG05436.1 - 0.094 12.9 0.0 0.34 11.1 0.0 2.0 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase Alpha_kinase PF02816.18 EGG05438.1 - 7.3e-08 32.8 0.0 9.4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family DUF1509 PF07420.11 EGG05441.1 - 0.025 13.5 0.2 0.036 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Golgin_A5 PF09787.9 EGG05442.1 - 0.064 12.7 9.3 0.17 11.3 9.3 1.7 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 EGG05442.1 - 0.069 12.5 5.6 0.14 11.5 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4636 PF15468.6 EGG05442.1 - 2.9 7.5 25.5 0.32 10.7 11.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4636) SPT16 PF08644.11 EGG05442.1 - 6.9 6.8 10.0 1.1 9.4 0.1 2.6 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) PI3K_1B_p101 PF10486.9 EGG05442.1 - 7.4 4.2 19.1 12 3.6 19.1 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Phage_Arf PF17585.2 EGG05443.1 - 0.018 14.9 0.3 0.029 14.3 0.3 1.3 1 0 0 1 1 1 0 Accessory recombination function protein Rhodanese PF00581.20 EGG05444.1 - 1.7e-09 38.2 0.0 2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_L28e PF01778.17 EGG05446.1 - 1e-21 77.8 0.0 1.2e-21 77.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family PH_10 PF15411.6 EGG05447.1 - 2.2e-35 121.6 0.1 5.1e-35 120.4 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EGG05447.1 - 7.7e-35 120.8 0.1 1.2e-34 120.1 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 EGG05447.1 - 1.3e-12 47.5 0.0 2.5e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.11 EGG05447.1 - 6.4e-09 35.9 0.1 0.0012 19.1 0.0 2.9 2 1 1 3 3 3 2 CDC24 Calponin DUF3915 PF13054.6 EGG05447.1 - 0.094 12.7 0.7 0.27 11.2 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) PH PF00169.29 EGG05447.1 - 0.11 13.1 0.1 0.27 11.8 0.1 1.7 1 0 0 1 1 1 0 PH domain SAM_PNT PF02198.16 EGG05448.1 - 0.022 14.7 0.0 0.08 12.9 0.0 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Ras PF00071.22 EGG05450.1 - 2.7e-52 176.6 0.0 3.3e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG05450.1 - 8.3e-24 84.1 0.0 1.6e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG05450.1 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG05450.1 - 0.0012 18.4 0.3 0.0093 15.5 0.0 2.3 1 1 1 3 3 3 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGG05450.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGG05450.1 - 0.033 14.6 0.0 0.064 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 EGG05450.1 - 0.061 12.7 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Vps36_ESCRT-II PF11605.8 EGG05451.1 - 0.0086 16.2 0.0 0.027 14.6 0.0 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 EGG05451.1 - 0.039 13.8 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 GRAM domain VRP3 PF03536.15 EGG05454.1 - 0.099 12.1 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein zf-ANAPC11 PF12861.7 EGG05456.1 - 2e-39 133.6 5.3 2.5e-39 133.2 5.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGG05456.1 - 2.5e-21 75.7 12.2 3.8e-21 75.1 12.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGG05456.1 - 3.5e-05 24.0 14.8 0.0004 20.7 14.8 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGG05456.1 - 0.033 14.0 12.6 0.14 12.1 12.6 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGG05456.1 - 0.11 12.1 12.2 0.33 10.6 12.2 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EGG05456.1 - 0.23 11.5 12.4 0.43 10.6 12.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.6 EGG05456.1 - 0.3 11.3 6.9 0.49 10.6 6.9 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.6 EGG05456.1 - 1.5 8.8 14.2 25 4.9 14.4 2.7 1 1 1 2 2 2 0 zinc-RING finger domain RINGv PF12906.7 EGG05456.1 - 2.1 8.5 11.9 12 6.1 11.9 2.2 1 1 0 1 1 1 0 RING-variant domain zf-RING_11 PF17123.5 EGG05456.1 - 2.3 8.1 14.9 19 5.1 14.9 2.2 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 EGG05456.1 - 2.6 8.3 13.2 7.2 6.9 13.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 EGG05456.1 - 8.7 6.3 16.6 2.6 8.0 11.2 2.5 1 1 1 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Mur_ligase_M PF08245.12 EGG05457.1 - 1.3e-07 31.8 0.1 2.9e-07 30.7 0.1 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EGG05457.1 - 0.0062 16.8 0.0 0.042 14.1 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain PGK PF00162.19 EGG05457.1 - 0.087 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase Lin0512_fam PF09585.10 EGG05459.1 - 0.1 12.6 0.2 19 5.3 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) RNA_pol_3_Rpc31 PF11705.8 EGG05460.1 - 1.3 9.2 13.5 1.4 9.1 13.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 EGG05460.1 - 3.2 7.1 13.9 3.9 6.8 13.9 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EGG05460.1 - 7.5 4.5 16.7 8.2 4.4 16.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Steroid_dh PF02544.16 EGG05461.1 - 1.9e-22 79.9 0.1 4.3e-20 72.2 0.1 2.3 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Hist_deacetyl PF00850.19 EGG05463.1 - 8.4e-61 206.1 0.0 1.2e-60 205.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain zf-UBP PF02148.19 EGG05465.1 - 0.12 12.7 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein TruB_C PF09142.11 EGG05465.1 - 0.65 9.8 2.5 0.95 9.3 0.9 2.1 1 1 1 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Apolipoprotein PF01442.18 EGG05466.1 - 0.017 15.0 2.7 0.12 12.2 0.9 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain LXG PF04740.12 EGG05466.1 - 0.048 13.4 0.9 0.092 12.4 0.9 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF4455 PF14643.6 EGG05466.1 - 0.05 12.3 0.2 0.093 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Focal_AT PF03623.13 EGG05466.1 - 0.11 12.5 1.7 3.1 7.8 0.6 2.6 2 0 0 2 2 2 0 Focal adhesion targeting region DUF883 PF05957.13 EGG05466.1 - 0.26 11.9 4.6 0.76 10.4 0.3 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.12 EGG05466.1 - 0.35 10.9 1.9 0.79 9.8 1.9 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 EGG05466.1 - 1.8 8.6 4.6 12 5.9 0.6 2.7 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) BAR PF03114.18 EGG05468.1 - 2.2e-43 148.6 6.7 2.9e-43 148.3 6.7 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 EGG05468.1 - 0.0039 17.0 0.0 0.0078 16.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGG05468.1 - 0.0052 16.4 0.0 0.014 15.0 0.0 1.8 1 0 0 1 1 1 1 SH3 domain BAR_2 PF10455.9 EGG05468.1 - 0.0085 15.3 8.1 0.026 13.7 8.1 1.8 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking FAD_binding_9 PF08021.11 EGG05468.1 - 0.23 11.6 1.1 38 4.5 0.0 3.1 3 0 0 3 3 3 0 Siderophore-interacting FAD-binding domain Pollen_allerg_1 PF01357.21 EGG05470.1 - 0.00062 19.7 1.9 0.00071 19.5 0.2 1.9 2 0 0 2 2 2 1 Pollen allergen Barwin PF00967.17 EGG05470.1 - 0.00094 19.0 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Barwin family Mo-co_dimer PF03404.16 EGG05470.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain TSP_NTD PF17804.1 EGG05471.1 - 0.00092 19.5 1.6 0.002 18.4 1.6 1.5 1 0 0 1 1 1 1 Tail specific protease N-terminal domain Evr1_Alr PF04777.13 EGG05472.1 - 0.095 13.2 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 Erv1 / Alr family TPR_2 PF07719.17 EGG05475.1 - 0.00046 20.1 0.2 0.15 12.3 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG05475.1 - 0.0005 19.8 0.5 0.14 12.1 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG05475.1 - 0.004 17.1 0.0 1.6 9.0 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat DAHP_synth_1 PF00793.20 EGG05476.1 - 4.6e-97 324.2 0.0 5.7e-97 323.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DNA_ligase_A_M PF01068.21 EGG05477.1 - 2.7e-30 105.6 0.2 6.7e-30 104.3 0.2 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGG05477.1 - 5.2e-15 56.2 0.0 1.2e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 EGG05477.1 - 1.2e-05 25.7 0.1 5.5e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 EGG05477.1 - 0.024 14.5 0.1 0.051 13.4 0.1 1.5 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain Ish1 PF10281.9 EGG05479.1 - 6.3e-108 352.8 58.0 6e-14 52.1 0.4 11.3 11 0 0 11 11 11 11 Putative stress-responsive nuclear envelope protein HeH PF12949.7 EGG05479.1 - 8.8e-13 47.7 3.4 0.16 11.7 0.0 7.7 8 0 0 8 8 8 4 HeH/LEM domain SAP PF02037.27 EGG05479.1 - 8e-07 28.7 0.0 26 4.7 0.0 7.4 9 0 0 9 9 8 0 SAP domain Slx4 PF09494.10 EGG05479.1 - 5.8e-05 23.0 4.2 1.9 8.5 0.0 5.6 6 1 1 7 7 7 1 Slx4 endonuclease TilS PF09179.11 EGG05479.1 - 7.1e-05 23.2 0.0 1.1 9.7 0.0 4.8 5 0 0 5 5 5 1 TilS substrate binding domain LEM PF03020.15 EGG05479.1 - 0.0032 17.0 0.0 12 5.6 0.0 5.0 6 0 0 6 6 6 0 LEM domain ABATE PF07336.11 EGG05479.1 - 0.011 16.4 3.7 9.6 6.9 0.1 4.8 3 1 0 3 3 3 0 Putative stress-induced transcription regulator PrkA PF06798.12 EGG05479.1 - 0.024 14.3 6.0 18 4.9 0.1 4.3 3 1 1 4 4 4 0 PrkA serine protein kinase C-terminal domain EutB PF06751.11 EGG05479.1 - 0.076 11.8 1.1 4.3 6.0 0.1 3.6 4 1 1 5 5 5 0 Ethanolamine ammonia lyase large subunit (EutB) DUF3921 PF13060.6 EGG05479.1 - 0.18 11.9 1.2 4.5 7.4 0.0 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF3921) SLATT_4 PF18186.1 EGG05479.1 - 0.26 10.9 6.9 4.3 7.0 0.1 4.4 4 1 1 5 5 5 0 SMODS and SLOG-associating 2TM effector domain family 4 RRF PF01765.19 EGG05479.1 - 0.46 10.4 2.2 7.5 6.5 0.0 3.6 4 0 0 4 4 4 0 Ribosome recycling factor DGOK PF05035.12 EGG05479.1 - 1.1 8.1 3.4 12 4.6 0.1 3.1 3 0 0 3 3 3 0 2-keto-3-deoxy-galactonokinase SAM_1 PF00536.30 EGG05479.1 - 1.1 9.8 13.9 29 5.2 0.4 6.4 7 1 0 7 7 6 0 SAM domain (Sterile alpha motif) RRP14 PF15459.6 EGG05479.1 - 1.3 9.7 5.1 8 7.1 0.2 3.2 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 SAM_2 PF07647.17 EGG05479.1 - 6.1 7.0 14.5 31 4.8 0.1 6.9 8 0 0 8 8 7 0 SAM domain (Sterile alpha motif) Sod_Fe_C PF02777.18 EGG05480.1 - 2.8e-33 114.1 0.2 5.9e-33 113.1 0.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGG05480.1 - 4.5e-32 110.4 4.7 4.5e-32 110.4 4.7 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF2807 PF10988.8 EGG05480.1 - 0.092 12.5 0.1 0.16 11.7 0.1 1.4 1 1 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Mito_carr PF00153.27 EGG05482.1 - 5.9e-63 208.8 2.8 4.4e-21 74.6 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGG05482.1 - 0.073 12.2 1.2 2.9 7.0 0.0 3.0 2 2 1 3 3 3 0 Gammaproteobacterial serine protease DUF2442 PF10387.9 EGG05483.1 - 0.027 14.8 0.0 0.029 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) HMG_box PF00505.19 EGG05484.1 - 1.5e-25 89.4 1.0 1.8e-25 89.1 1.0 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGG05484.1 - 2.4e-17 63.3 0.7 3e-17 63.0 0.7 1.1 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 EGG05484.1 - 0.0039 17.1 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.13 EGG05484.1 - 0.017 15.7 0.2 0.022 15.3 0.1 1.3 1 1 0 1 1 1 0 YABBY protein PHINT_rpt PF14882.6 EGG05484.1 - 0.054 13.8 0.7 0.091 13.1 0.1 1.7 2 0 0 2 2 2 0 Phage-integrase repeat unit Oxysterol_BP PF01237.18 EGG05486.1 - 3.2e-65 220.4 2.1 9.3e-63 212.3 2.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Glyco_hydro_18 PF00704.28 EGG05487.1 - 2e-43 149.3 0.0 2.2e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 COesterase PF00135.28 EGG05491.1 - 0.13 11.1 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family MFS_2 PF13347.6 EGG05492.1 - 0.14 10.7 12.5 0.013 14.0 6.3 2.4 2 1 0 2 2 2 0 MFS/sugar transport protein Sigma_reg_N PF13800.6 EGG05492.1 - 0.3 11.4 0.0 0.3 11.4 0.0 5.1 4 1 1 5 5 5 0 Sigma factor regulator N-terminal Diphthami_syn_2 PF01902.17 EGG05493.1 - 9.5e-42 143.0 0.0 1.6e-38 132.5 0.0 2.0 1 1 0 1 1 1 1 Diphthamide synthase Ribosomal_S27e PF01667.17 EGG05495.1 - 1.2e-30 104.9 4.8 1.5e-30 104.6 4.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 EGG05495.1 - 0.029 14.8 1.6 0.12 12.8 1.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) TF_Zn_Ribbon PF08271.12 EGG05495.1 - 0.14 11.7 3.1 0.2 11.2 3.1 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Mu-like_Com PF10122.9 EGG05495.1 - 0.44 10.0 3.5 6.4 6.3 0.6 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com Sec10 PF07393.11 EGG05496.1 - 2.5e-213 710.5 0.0 2.9e-213 710.3 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Jnk-SapK_ap_N PF09744.9 EGG05496.1 - 0.011 16.0 1.4 0.059 13.6 0.0 2.5 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 EGG05496.1 - 0.011 15.7 0.5 0.034 14.2 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GCN5L1 PF06320.13 EGG05496.1 - 0.11 12.6 0.9 5.2 7.3 0.0 3.0 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Herpes_capsid PF06112.11 EGG05496.1 - 3.2 7.8 5.0 5.1 7.1 1.5 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein P16-Arc PF04699.14 EGG05498.1 - 2.5e-45 154.6 0.0 2.8e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 EGG05498.1 - 0.033 14.5 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 Dip2/Utp12 Family Pkinase PF00069.25 EGG05499.1 - 2.9e-64 217.0 0.0 3.5e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG05499.1 - 1.6e-31 109.5 0.0 2.2e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG05499.1 - 1e-05 24.7 0.1 1.4e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGG05499.1 - 0.00024 20.5 0.1 0.00072 19.0 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG05499.1 - 0.00058 19.8 0.0 0.0012 18.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGG05499.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGG05499.1 - 0.027 13.8 0.0 0.056 12.7 0.0 1.4 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EGG05499.1 - 0.034 13.7 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Alpha_kinase PF02816.18 EGG05502.1 - 1.3e-16 61.2 0.0 1.5e-16 61.1 0.0 1.0 1 0 0 1 1 1 1 Alpha-kinase family CFEM PF05730.11 EGG05503.1 - 1.4e-11 44.3 9.3 2.2e-11 43.7 9.3 1.3 1 0 0 1 1 1 1 CFEM domain Cwf_Cwc_15 PF04889.12 EGG05505.1 - 9.2 5.9 23.5 0.94 9.2 12.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ORC6 PF05460.13 EGG05506.1 - 0.0068 15.7 9.8 0.0094 15.3 9.8 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Adeno_PV PF03910.13 EGG05506.1 - 0.87 8.2 6.1 1.2 7.7 6.1 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV Aldedh PF00171.22 EGG05510.1 - 2.3e-68 230.8 0.0 4.3e-68 229.9 0.0 1.3 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Phage_min_cap2 PF06152.11 EGG05510.1 - 0.058 12.3 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 MFAP1 PF06991.11 EGG05511.1 - 6.1e-24 85.1 9.5 6.1e-24 85.1 9.5 2.2 2 0 0 2 2 2 1 Microfibril-associated/Pre-mRNA processing Transglut_N PF00868.20 EGG05511.1 - 0.0057 17.0 1.1 0.014 15.8 1.1 1.6 1 1 0 1 1 1 1 Transglutaminase family AF-4 PF05110.13 EGG05511.1 - 0.014 13.5 46.1 0.0069 14.5 31.4 2.2 1 1 1 2 2 2 0 AF-4 proto-oncoprotein Macoilin PF09726.9 EGG05511.1 - 0.36 9.3 20.3 0.51 8.8 20.3 1.2 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 EGG05511.1 - 0.85 7.8 11.5 0.91 7.7 11.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ndc1_Nup PF09531.10 EGG05511.1 - 2 7.0 16.0 2.6 6.7 16.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 EGG05511.1 - 6.9 5.0 21.6 8.1 4.8 21.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Adap_comp_sub PF00928.21 EGG05512.1 - 5e-26 91.6 0.0 5.5e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family IlvN PF07991.12 EGG05513.1 - 7.5e-47 159.0 0.0 1.6e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EGG05513.1 - 6.7e-40 136.7 0.0 1.9e-39 135.2 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 EGG05513.1 - 0.041 14.0 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGG05513.1 - 0.065 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CotJA PF11007.8 EGG05513.1 - 0.14 12.0 0.0 0.5 10.2 0.0 1.9 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) ACC_central PF08326.12 EGG05514.1 - 5.4e-244 811.8 0.0 8.1e-244 811.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EGG05514.1 - 2.4e-172 574.0 0.0 3.3e-172 573.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EGG05514.1 - 2.3e-51 174.3 0.1 4.3e-51 173.4 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGG05514.1 - 4e-29 101.4 0.1 9.5e-29 100.2 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGG05514.1 - 4.3e-22 78.3 0.0 2.3e-20 72.7 0.0 2.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGG05514.1 - 6.3e-15 54.8 0.1 1.6e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGG05514.1 - 0.00017 21.2 0.0 0.00047 19.7 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EGG05514.1 - 0.00097 19.2 0.0 0.0046 17.0 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EGG05514.1 - 0.0015 18.3 0.0 0.0064 16.3 0.0 2.0 2 0 0 2 2 2 1 Biotin-lipoyl like PAXNEB PF05625.11 EGG05514.1 - 0.044 12.9 0.1 0.27 10.3 0.0 2.1 2 0 0 2 2 2 0 PAXNEB protein ATPgrasp_Ter PF15632.6 EGG05514.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF2977 PF11192.8 EGG05516.1 - 0.17 12.0 0.1 0.31 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2977) MutS_V PF00488.21 EGG05517.1 - 2.9e-44 151.3 0.1 5.1e-44 150.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGG05517.1 - 3.4e-24 86.1 0.3 8e-24 84.9 0.3 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EGG05517.1 - 3.3e-07 30.6 0.0 9.9e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV Glucan_synthase PF02364.15 EGG05518.1 - 1.2e-105 354.5 14.3 9e-52 176.3 3.2 3.5 1 1 3 4 4 4 4 1,3-beta-glucan synthase component Syntaxin-18_N PF10496.9 EGG05518.1 - 0.0076 16.5 0.3 0.025 14.8 0.0 2.0 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Comm PF15957.5 EGG05518.1 - 2.3 8.6 8.7 9.7 6.6 0.4 3.3 2 1 0 2 2 2 0 Commissureless Zn_clus PF00172.18 EGG05521.1 - 0.27 11.4 7.6 3.7 7.7 2.1 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Adeno_knob PF00541.17 EGG05522.1 - 0.057 13.2 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Adenoviral fibre protein (knob domain) BRE1 PF08647.11 EGG05524.1 - 1 9.5 5.4 0.19 11.8 0.8 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Sad1_UNC PF07738.13 EGG05526.1 - 3.1e-27 95.2 0.0 4.5e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Fra10Ac1 PF09725.9 EGG05527.1 - 6e-14 52.2 0.2 7.3e-14 51.9 0.2 1.1 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Fra10Ac1 PF09725.9 EGG05528.1 - 1.4e-20 73.6 0.1 1.9e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Hepatitis_core PF00906.20 EGG05528.1 - 4.1 6.9 15.5 6.3 6.3 15.5 1.4 1 0 0 1 1 1 0 Hepatitis core antigen Caleosin PF05042.13 EGG05530.1 - 1.7e-11 44.4 0.4 2.5e-05 24.3 0.2 2.3 2 0 0 2 2 2 2 Caleosin related protein PIF1 PF05970.14 EGG05531.1 - 1.6e-24 86.7 0.7 2.2e-24 86.3 0.7 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EGG05531.1 - 2.8e-11 43.5 0.3 4.5e-11 42.8 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG05531.1 - 3.6e-08 33.9 0.2 7.2e-08 32.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG05531.1 - 0.00021 21.8 0.1 0.00036 21.0 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 EGG05531.1 - 0.00037 20.0 0.3 0.00061 19.3 0.3 1.2 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 EGG05531.1 - 0.00041 19.7 0.0 0.00041 19.7 0.0 2.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 EGG05531.1 - 0.00048 20.1 0.2 0.00084 19.3 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 EGG05531.1 - 0.0021 18.0 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EGG05531.1 - 0.004 17.4 0.1 0.011 16.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EGG05531.1 - 0.0053 16.5 0.2 0.18 11.6 0.1 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase ABC_tran PF00005.27 EGG05531.1 - 0.0066 17.0 0.2 0.04 14.4 0.1 2.3 3 0 0 3 3 3 1 ABC transporter AAA_7 PF12775.7 EGG05531.1 - 0.0069 15.9 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EGG05531.1 - 0.031 14.7 0.0 0.083 13.3 0.0 1.9 1 1 0 1 1 1 0 RNA helicase DAP3 PF10236.9 EGG05531.1 - 0.036 13.2 0.1 0.055 12.6 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TsaE PF02367.17 EGG05531.1 - 0.037 14.0 0.1 0.067 13.2 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EGG05531.1 - 0.058 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EGG05531.1 - 0.062 12.3 0.1 0.078 12.0 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 EGG05531.1 - 0.074 13.1 0.1 0.15 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EGG05531.1 - 0.087 13.2 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 EGG05531.1 - 0.095 12.2 0.4 0.18 11.3 0.4 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain TrwB_AAD_bind PF10412.9 EGG05531.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 EGG05531.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGG05531.1 - 0.13 12.0 0.4 13 5.4 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 EGG05531.1 - 0.19 11.6 0.1 0.52 10.2 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Ndc1_Nup PF09531.10 EGG05531.1 - 1.3 7.7 8.1 1.6 7.4 8.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HSP90 PF00183.18 EGG05533.1 - 0.0043 16.0 0.1 0.0048 15.9 0.1 1.0 1 0 0 1 1 1 1 Hsp90 protein EVI2A PF05399.11 EGG05534.1 - 0.073 12.6 6.2 0.14 11.8 6.2 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) NST1 PF13945.6 EGG05534.1 - 1.8 8.6 7.3 3.1 7.8 7.3 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator zf_CCCH_4 PF18345.1 EGG05535.1 - 1.5e-05 24.8 9.9 0.0095 16.0 1.1 3.2 2 2 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EGG05535.1 - 8.1e-05 22.3 11.3 0.0071 16.1 0.9 3.0 2 1 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 EGG05535.1 - 0.00076 20.1 0.1 0.00076 20.1 0.1 3.5 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 EGG05535.1 - 0.0012 18.7 6.5 0.025 14.5 0.4 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EGG05535.1 - 0.0098 16.1 4.2 0.068 13.4 4.1 2.3 1 1 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGG05535.1 - 0.058 13.9 8.8 1.1 9.8 1.4 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Herpes_LMP1 PF05297.11 EGG05535.1 - 9 5.4 17.9 0.12 11.6 4.5 2.4 2 1 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) UQ_con PF00179.26 EGG05537.1 - 2.7e-17 62.7 0.0 2.9e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGG05537.1 - 0.11 12.8 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain Peptidase_S10 PF00450.22 EGG05541.1 - 6.5e-109 365.1 0.2 8e-109 364.8 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase 3Beta_HSD PF01073.19 EGG05542.1 - 6.1e-69 232.1 0.0 8.2e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGG05542.1 - 4.5e-31 108.1 0.0 6.2e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG05542.1 - 6.5e-18 65.2 0.0 4.4e-17 62.5 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGG05542.1 - 1.3e-12 47.4 0.0 1.1e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EGG05542.1 - 2.1e-09 37.0 0.0 7.2e-09 35.2 0.0 1.8 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGG05542.1 - 7e-09 35.2 0.0 1.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGG05542.1 - 2.1e-07 31.0 0.0 4.7e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Tetraspanin PF00335.20 EGG05543.1 - 0.8 9.4 0.0 0.8 9.4 0.0 3.1 2 1 0 2 2 2 0 Tetraspanin family DUF3613 PF12266.8 EGG05544.1 - 0.04 13.7 1.3 0.082 12.7 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) DUF3364 PF11844.8 EGG05544.1 - 0.079 13.2 0.6 2.8 8.2 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) R3H PF01424.22 EGG05547.1 - 6.5e-11 42.0 0.1 1.1e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 EGG05547.1 - 0.00011 22.1 24.6 0.00062 19.8 9.3 14.6 16 0 0 16 16 16 7 NF-X1 type zinc finger TPR_1 PF00515.28 EGG05548.1 - 5.3e-26 89.3 5.5 0.00052 19.7 0.0 9.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGG05548.1 - 4.8e-25 85.6 7.0 0.00028 20.8 0.0 10.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGG05548.1 - 2.7e-18 64.6 7.5 0.0011 19.0 0.0 9.1 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGG05548.1 - 1e-14 53.4 2.3 0.11 12.6 0.1 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGG05548.1 - 2.8e-14 52.6 0.1 2.1 9.4 0.0 8.9 6 2 3 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG05548.1 - 6.2e-13 49.1 3.6 0.0083 16.6 0.0 7.8 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGG05548.1 - 3.8e-12 46.3 10.1 0.00088 19.5 0.0 7.8 7 2 2 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGG05548.1 - 1.2e-11 45.1 0.0 0.013 16.1 0.0 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGG05548.1 - 6.5e-11 41.7 4.6 0.0033 17.1 0.0 6.5 5 2 2 7 7 7 3 TPR repeat TPR_17 PF13431.6 EGG05548.1 - 5.6e-09 35.8 2.8 0.45 11.0 0.0 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG05548.1 - 2.8e-06 27.6 6.9 0.59 10.9 0.0 7.1 8 0 0 8 8 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGG05548.1 - 1.3e-05 24.9 9.6 1.3 9.0 0.1 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG05548.1 - 0.0006 20.0 0.7 0.065 13.5 0.1 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 EGG05548.1 - 0.0081 15.6 0.4 0.29 10.5 0.1 2.8 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 EGG05548.1 - 0.016 15.3 0.3 3.8 7.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat WbqC PF08889.11 EGG05548.1 - 0.024 14.5 0.0 0.069 13.0 0.0 1.8 1 0 0 1 1 1 0 WbqC-like protein family TPR_20 PF14561.6 EGG05548.1 - 0.04 14.2 0.3 21 5.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 EGG05548.1 - 0.053 12.5 0.1 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_3 PF07720.12 EGG05548.1 - 5.6 7.1 6.8 15 5.7 1.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.27 EGG05549.1 - 8.8e-35 118.5 4.0 6.3e-17 61.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M28 PF04389.17 EGG05550.1 - 1.9e-13 50.5 0.0 5.1e-13 49.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 Asp1 PF16993.5 EGG05550.1 - 0.029 13.6 0.1 0.043 13.0 0.1 1.2 1 0 0 1 1 1 0 Accessory Sec system protein Asp1 DUF3290 PF11694.8 EGG05550.1 - 0.038 14.0 1.4 0.068 13.1 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) UCR_TM PF02921.14 EGG05551.1 - 2.3e-11 44.0 1.3 7.3e-11 42.4 1.3 1.8 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 EGG05551.1 - 1e-10 41.4 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF4062 PF13271.6 EGG05552.1 - 0.15 12.5 0.0 2 8.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) SNF2_N PF00176.23 EGG05553.1 - 4.2e-09 35.6 0.1 8.3e-09 34.6 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.23 EGG05554.1 - 3.7e-43 147.6 0.0 5.9e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG05554.1 - 8.1e-16 58.3 0.0 1.8e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EGG05554.1 - 8.8e-05 21.8 0.3 0.00039 19.7 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EGG05554.1 - 0.009 16.0 0.0 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Clathrin PF00637.20 EGG05555.1 - 1e-12 48.1 5.8 1.2e-11 44.7 0.3 3.6 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 EGG05555.1 - 0.0006 19.8 5.9 0.0012 18.8 5.9 1.6 1 0 0 1 1 1 1 Zinc-finger VPS11_C PF12451.8 EGG05555.1 - 0.0018 18.5 0.3 0.0018 18.5 0.3 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.6 EGG05555.1 - 0.0034 17.7 7.2 0.0083 16.4 7.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGG05555.1 - 0.057 13.4 6.7 0.13 12.2 6.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_1 PF14446.6 EGG05555.1 - 0.42 10.6 2.6 0.92 9.5 2.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.6 EGG05555.1 - 0.75 9.9 3.7 1.9 8.6 3.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG05555.1 - 1.9 8.4 8.0 7.8 6.4 8.1 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGG05555.1 - 2.2 8.1 11.4 0.12 12.1 5.0 2.2 2 0 0 2 2 2 0 RING-like zinc finger UQ_con PF00179.26 EGG05560.1 - 1.2e-45 154.6 0.0 1.6e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGG05560.1 - 1.2e-05 25.5 0.0 1.8e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EGG05560.1 - 0.0012 18.7 0.2 0.0024 17.7 0.2 1.5 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 EGG05560.1 - 0.03 14.0 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Tmemb_cc2 PF10267.9 EGG05562.1 - 3.7 6.6 12.5 5.8 6.0 12.5 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF4490 PF14892.6 EGG05563.1 - 0.053 13.6 0.0 0.21 11.7 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4490) LRR_4 PF12799.7 EGG05566.1 - 0.096 13.2 5.9 1.1 9.7 0.7 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRRNT PF01462.18 EGG05566.1 - 0.3 10.8 1.7 33 4.3 0.0 3.6 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain DASH_Dad3 PF08656.10 EGG05568.1 - 3.4e-21 75.1 0.4 4.4e-21 74.8 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 NAD_binding_2 PF03446.15 EGG05569.1 - 1.4e-31 109.8 0.4 2.8e-30 105.6 0.4 2.1 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGG05569.1 - 1.1e-25 90.2 0.0 2.3e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Got1 PF04178.12 EGG05571.1 - 1.1e-28 99.9 22.8 1.2e-28 99.7 22.8 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family Phage_holin_2_4 PF16082.5 EGG05571.1 - 5.4 6.8 6.2 11 5.8 6.2 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like CIA30 PF08547.12 EGG05572.1 - 7.3e-24 84.6 0.0 9.4e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) GIT_SHD PF08518.11 EGG05572.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT zf-CCHC PF00098.23 EGG05573.1 - 0.0055 16.7 2.4 0.0055 16.7 2.4 2.1 2 0 0 2 2 2 1 Zinc knuckle ArfGap PF01412.18 EGG05574.1 - 3e-34 117.6 0.3 7.8e-34 116.3 0.3 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Zip PF02535.22 EGG05575.1 - 4.2e-15 55.8 25.2 2.3e-10 40.2 21.2 4.0 1 1 1 2 2 2 2 ZIP Zinc transporter SieB PF14163.6 EGG05575.1 - 0.15 11.5 0.6 0.87 9.1 0.0 2.2 2 0 0 2 2 2 0 Super-infection exclusion protein B TPR_2 PF07719.17 EGG05577.1 - 0.00056 19.8 0.3 0.0016 18.4 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG05577.1 - 0.033 14.8 0.0 0.63 10.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG05577.1 - 0.033 15.0 0.1 0.52 11.3 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Fer4_13 PF13370.6 EGG05577.1 - 0.059 13.9 0.0 0.094 13.3 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I HP_OMP PF01856.17 EGG05577.1 - 0.075 13.1 0.1 0.095 12.8 0.1 1.1 1 0 0 1 1 1 0 Helicobacter outer membrane protein TPR_8 PF13181.6 EGG05577.1 - 0.079 13.2 0.1 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2709 PF10915.8 EGG05578.1 - 0.089 12.0 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) Barwin PF00967.17 EGG05581.1 - 0.097 12.5 1.7 0.97 9.3 0.2 2.4 2 0 0 2 2 2 0 Barwin family SNARE_assoc PF09335.11 EGG05584.1 - 0.06 13.8 0.0 0.083 13.4 0.0 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein Cwf_Cwc_15 PF04889.12 EGG05588.1 - 0.00085 19.1 6.3 0.0011 18.7 6.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SURF2 PF05477.11 EGG05588.1 - 0.48 10.1 2.3 0.63 9.7 2.3 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NOA36 PF06524.12 EGG05589.1 - 7.9 5.7 12.2 7.7 5.7 12.2 1.2 1 0 0 1 1 1 0 NOA36 protein Orthopox_B11R PF07033.11 EGG05591.1 - 0.13 12.1 0.1 0.37 10.6 0.1 1.8 1 1 0 1 1 1 0 Orthopoxvirus B11R protein COG5 PF10392.9 EGG05592.1 - 0.031 14.5 5.7 0.12 12.5 5.6 1.9 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Cep57_CLD PF14073.6 EGG05592.1 - 0.033 14.2 8.8 0.059 13.4 8.2 1.6 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 AvrPtoB-E3_ubiq PF09046.10 EGG05592.1 - 0.08 13.2 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 AvrPtoB E3 ubiquitin ligase DUF2730 PF10805.8 EGG05592.1 - 0.4 10.8 3.6 0.97 9.6 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DHR10 PF18595.1 EGG05592.1 - 0.43 10.6 8.4 0.81 9.8 8.4 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Tropomyosin_1 PF12718.7 EGG05592.1 - 0.51 10.5 8.1 1.1 9.4 8.1 1.4 1 0 0 1 1 1 0 Tropomyosin like LPP PF04728.13 EGG05592.1 - 0.52 10.7 4.9 12 6.4 0.5 3.1 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 EGG05592.1 - 0.73 9.9 5.7 1.7 8.7 5.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 EGG05592.1 - 0.79 9.9 9.8 1.6 8.9 9.8 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) YabA PF06156.13 EGG05592.1 - 2.2 9.0 4.3 6.1 7.5 4.3 1.7 1 1 0 1 1 1 0 Initiation control protein YabA bZIP_2 PF07716.15 EGG05592.1 - 3.7 7.7 7.5 40 4.4 0.1 3.2 2 1 1 3 3 3 0 Basic region leucine zipper SlyX PF04102.12 EGG05592.1 - 3.9 8.1 11.8 3.9 8.2 5.0 2.7 1 1 1 2 2 2 0 SlyX APC_N_CC PF16689.5 EGG05592.1 - 5.2 7.2 6.3 1.1 9.4 2.2 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF16 PF01519.16 EGG05592.1 - 6.6 7.3 8.5 20 5.8 1.6 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 Tropomyosin PF00261.20 EGG05593.1 - 1.3e-06 28.0 6.8 1.8e-06 27.5 6.8 1.2 1 0 0 1 1 1 1 Tropomyosin PspA_IM30 PF04012.12 EGG05593.1 - 1e-05 25.2 7.0 0.00029 20.5 0.4 2.0 1 1 1 2 2 2 2 PspA/IM30 family DUF1664 PF07889.12 EGG05593.1 - 0.0083 16.2 6.7 0.012 15.7 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) SOGA PF11365.8 EGG05593.1 - 0.02 16.0 6.3 0.19 12.9 5.1 2.1 1 1 1 2 2 2 0 Protein SOGA FlaC_arch PF05377.11 EGG05593.1 - 0.025 15.0 4.6 0.073 13.5 0.2 2.9 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 EGG05593.1 - 0.06 13.8 7.1 0.23 12.0 7.1 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 DDE_Tnp_IS66 PF03050.14 EGG05593.1 - 0.076 12.5 2.9 0.095 12.2 2.9 1.1 1 0 0 1 1 1 0 Transposase IS66 family ORF6C PF10552.9 EGG05593.1 - 0.1 12.7 0.1 0.1 12.7 0.1 2.2 2 0 0 2 2 2 0 ORF6C domain PRKG1_interact PF15898.5 EGG05593.1 - 0.15 12.9 9.5 0.44 11.5 9.5 1.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Tropomyosin_1 PF12718.7 EGG05593.1 - 0.2 11.8 10.9 0.38 10.9 10.9 1.5 1 1 0 1 1 1 0 Tropomyosin like CLZ PF16526.5 EGG05593.1 - 0.21 12.0 9.7 3.5 8.0 2.0 2.9 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Exonuc_VII_L PF02601.15 EGG05593.1 - 0.23 11.0 5.1 0.26 10.8 5.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_II PF06009.12 EGG05593.1 - 0.26 11.3 6.9 1.1 9.3 6.9 1.9 1 1 1 2 2 2 0 Laminin Domain II SlyX PF04102.12 EGG05593.1 - 0.27 11.9 5.9 0.35 11.5 0.9 2.2 1 1 1 2 2 2 0 SlyX Z1 PF10593.9 EGG05593.1 - 0.28 10.6 5.4 0.33 10.4 5.4 1.2 1 0 0 1 1 1 0 Z1 domain CHD5 PF04420.14 EGG05593.1 - 0.3 10.9 4.6 0.24 11.2 2.4 2.0 1 1 1 2 2 2 0 CHD5-like protein BLOC1_2 PF10046.9 EGG05593.1 - 0.32 11.3 6.2 0.52 10.7 3.2 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med9 PF07544.13 EGG05593.1 - 0.36 10.9 5.8 0.42 10.7 4.7 1.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Atg14 PF10186.9 EGG05593.1 - 0.46 9.5 6.3 0.53 9.3 6.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GvpK PF05121.12 EGG05593.1 - 0.46 10.5 3.4 1.1 9.3 3.4 1.7 1 1 0 1 1 1 0 Gas vesicle protein K Tweety PF04906.13 EGG05593.1 - 0.47 9.1 1.5 0.59 8.7 1.5 1.1 1 0 0 1 1 1 0 Tweety Uds1 PF15456.6 EGG05593.1 - 0.49 10.6 10.3 10 6.3 10.3 2.4 1 1 0 1 1 1 0 Up-regulated During Septation XhlA PF10779.9 EGG05593.1 - 0.99 9.7 5.1 1.8 8.8 1.5 2.4 1 1 1 2 2 2 0 Haemolysin XhlA Fib_alpha PF08702.10 EGG05593.1 - 1.1 9.4 7.3 2.2 8.5 7.3 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Sec2p PF06428.11 EGG05593.1 - 1.4 9.0 12.6 4.3 7.4 2.3 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF1465 PF07323.12 EGG05593.1 - 1.6 8.6 7.3 0.3 10.9 2.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) UPF0242 PF06785.11 EGG05593.1 - 2.5 8.1 11.1 3.4 7.7 11.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPD52 PF04201.15 EGG05595.1 - 0.0012 18.5 6.6 0.0027 17.4 2.8 2.4 1 1 1 2 2 2 1 Tumour protein D52 family betaPIX_CC PF16523.5 EGG05595.1 - 0.0036 17.1 0.3 0.013 15.3 0.2 2.1 1 1 0 1 1 1 1 betaPIX coiled coil DUF1664 PF07889.12 EGG05595.1 - 0.018 15.1 5.5 0.094 12.8 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 EGG05595.1 - 0.45 8.4 7.4 0.71 7.8 7.4 1.2 1 0 0 1 1 1 0 Prominin Vps51 PF08700.11 EGG05595.1 - 0.71 10.0 7.7 0.18 11.9 3.4 2.3 2 0 0 2 2 2 0 Vps51/Vps67 Muted PF14942.6 EGG05595.1 - 1.3 9.3 13.5 0.27 11.6 8.4 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein YjbT PF17089.5 EGG05595.1 - 1.5 8.9 4.5 4.3 7.4 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family TMPIT PF07851.13 EGG05595.1 - 2.1 7.5 8.1 0.19 10.9 3.1 1.7 2 0 0 2 2 2 0 TMPIT-like protein Spc7 PF08317.11 EGG05595.1 - 6.4 5.6 16.7 0.47 9.3 10.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2730 PF10805.8 EGG05595.1 - 7.4 6.7 9.2 2.3 8.3 1.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Cep57_MT_bd PF06657.13 EGG05596.1 - 0.08 13.4 2.5 0.14 12.6 2.5 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 PorP_SprF PF11751.8 EGG05598.1 - 0.0011 18.5 0.9 0.0013 18.4 0.9 1.1 1 0 0 1 1 1 1 Type IX secretion system membrane protein PorP/SprF BLM10_mid PF16507.5 EGG05599.1 - 0.047 12.3 0.0 0.067 11.8 0.0 1.1 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region DUF2937 PF11157.8 EGG05600.1 - 0.099 12.3 0.1 0.18 11.5 0.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) tRNA_lig_kinase PF08303.11 EGG05601.1 - 2 8.5 5.9 0.4 10.7 1.5 2.0 2 0 0 2 2 2 0 tRNA ligase kinase domain Lectin_N PF03954.14 EGG05601.1 - 3.6 7.3 7.5 0.4 10.4 1.5 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF3556 PF12077.8 EGG05602.1 - 0.014 13.8 0.0 0.021 13.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) Fib_alpha PF08702.10 EGG05603.1 - 0.00064 19.9 0.4 0.00078 19.7 0.4 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Herpes_U30 PF04523.13 EGG05603.1 - 0.055 11.3 0.1 0.056 11.3 0.1 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 BTG PF07742.12 EGG05604.1 - 0.045 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 BTG family MCM PF00493.23 EGG05607.1 - 1.3e-97 325.4 0.0 2.3e-97 324.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGG05607.1 - 1.2e-38 131.8 0.2 2.1e-38 131.0 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGG05607.1 - 5.2e-28 97.3 3.0 9.8e-28 96.4 3.0 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGG05607.1 - 4.1e-17 62.6 0.2 1.2e-16 61.1 0.2 1.9 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 EGG05607.1 - 1.3e-08 35.0 0.0 4.3e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGG05607.1 - 1.4e-07 31.1 0.0 5.1e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGG05607.1 - 0.0002 21.2 0.0 0.0016 18.3 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGG05607.1 - 0.0013 18.5 0.1 0.85 9.3 0.0 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 EGG05607.1 - 0.0041 17.5 1.1 0.038 14.4 0.6 2.9 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 EGG05607.1 - 0.14 12.6 0.1 0.55 10.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ORMDL PF04061.14 EGG05608.1 - 2.6e-50 169.8 1.4 3.3e-50 169.4 1.4 1.1 1 0 0 1 1 1 1 ORMDL family Glft2_N PF17994.1 EGG05608.1 - 0.17 11.8 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 Galactofuranosyltransferase 2 N-terminal zf-AN1 PF01428.16 EGG05609.1 - 3.9e-17 62.1 26.9 1.6e-10 40.9 4.5 3.2 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EGG05609.1 - 0.19 12.1 13.7 0.066 13.6 3.2 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DUF3144 PF11342.8 EGG05610.1 - 0.096 13.0 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) DUF3144 PF11342.8 EGG05612.1 - 0.096 13.0 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) CxC5 PF18718.1 EGG05613.1 - 1e-31 109.4 4.6 1.8e-31 108.7 4.6 1.4 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Drf_GBD PF06371.13 EGG05615.1 - 1.6e-11 44.1 1.6 1.8e-10 40.7 0.1 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGG05615.1 - 5.3e-06 26.2 2.7 7.6e-06 25.7 0.9 2.3 2 1 0 2 2 2 1 Diaphanous FH3 Domain FH2 PF02181.23 EGG05616.1 - 2.3e-41 142.2 0.5 1.8e-32 112.9 0.1 2.5 2 1 0 2 2 2 2 Formin Homology 2 Domain zf-NADH-PPase PF09297.11 EGG05618.1 - 0.054 13.2 4.9 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Auto_anti-p27 PF06677.12 EGG05618.1 - 0.096 12.9 1.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Nudix_N_2 PF14803.6 EGG05618.1 - 0.17 11.8 4.6 3.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal SUKH-4 PF14435.6 EGG05619.1 - 0.024 14.7 0.1 0.033 14.2 0.1 1.3 1 0 0 1 1 1 0 SUKH-4 immunity protein Glyco_hydr_116N PF12215.8 EGG05620.1 - 0.0023 17.5 0.1 0.0038 16.8 0.1 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term TFIIF_alpha PF05793.12 EGG05621.1 - 2.2 6.8 33.0 3.6 6.0 33.0 1.5 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TssO PF17561.2 EGG05622.1 - 0.42 10.7 5.3 0.21 11.7 2.7 1.8 1 1 1 2 2 2 0 Type VI secretion system, TssO CDC24_OB3 PF17244.2 EGG05623.1 - 0.00077 19.2 0.0 0.00082 19.1 0.0 1.1 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 3 POT1 PF02765.17 EGG05623.1 - 0.0041 17.0 0.0 0.0054 16.6 0.0 1.2 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 EGG05623.1 - 0.042 13.8 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 Replication protein A OB domain tRNA_anti-codon PF01336.25 EGG05623.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF3605 PF12239.8 EGG05628.1 - 1e-07 32.4 0.5 3.9e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) IF-2B PF01008.17 EGG05629.1 - 6.3e-71 238.9 0.0 7.4e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1308 PF07000.11 EGG05629.1 - 0.086 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Ferric_reduct PF01794.19 EGG05631.1 - 2.2e-19 69.8 8.1 2.2e-19 69.8 8.1 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGG05631.1 - 1.3e-06 28.6 0.1 4.5e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EGG05631.1 - 0.0078 16.8 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 EGG05631.1 - 3.3 8.3 13.9 0.078 13.5 2.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) CDP-OH_P_transf PF01066.21 EGG05633.1 - 1.3e-10 41.9 0.2 3.6e-10 40.4 0.2 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PI_PP_I PF18363.1 EGG05636.1 - 0.031 14.5 0.2 0.93 9.7 0.0 2.8 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain F-box-like PF12937.7 EGG05636.1 - 0.074 12.9 1.5 0.31 10.9 0.2 2.5 2 0 0 2 2 2 0 F-box-like Proteasome PF00227.26 EGG05638.1 - 4.2e-59 199.2 0.0 5.8e-59 198.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGG05638.1 - 1e-13 50.7 0.1 1.9e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Helicase_C_3 PF13625.6 EGG05638.1 - 0.038 14.1 0.7 0.53 10.4 0.1 2.9 3 1 0 3 3 3 0 Helicase conserved C-terminal domain Laminin_EGF PF00053.24 EGG05639.1 - 1.1 9.4 8.5 4.1 7.6 1.1 2.6 2 1 0 2 2 2 0 Laminin EGF domain zf-B_box PF00643.24 EGG05640.1 - 1.3 9.2 6.9 0.89 9.8 0.3 3.0 3 0 0 3 3 3 0 B-box zinc finger zf-B_box PF00643.24 EGG05641.1 - 0.044 14.0 0.6 0.044 14.0 0.6 2.8 3 0 0 3 3 3 0 B-box zinc finger Baculo_F PF12259.8 EGG05641.1 - 0.19 10.2 3.0 1.1 7.7 1.8 2.0 2 0 0 2 2 2 0 Baculovirus F protein Thioredoxin_4 PF13462.6 EGG05642.1 - 3.8e-05 23.9 0.1 0.00015 21.9 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin ApoC-I PF04691.12 EGG05642.1 - 0.023 14.6 1.4 0.06 13.3 1.4 1.7 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) DUF4254 PF14063.6 EGG05642.1 - 0.09 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) DSBA PF01323.20 EGG05642.1 - 0.13 12.0 2.3 0.43 10.3 0.2 2.4 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Dynactin PF12455.8 EGG05643.1 - 2.8e-86 289.3 12.6 2.8e-86 289.3 12.6 4.2 4 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 EGG05643.1 - 1.2e-22 79.7 1.0 2e-22 79.0 1.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF730 PF05325.11 EGG05643.1 - 0.0077 16.3 0.3 0.0077 16.3 0.3 3.9 5 0 0 5 5 5 1 Protein of unknown function (DUF730) PGM_PMM_II PF02879.16 EGG05643.1 - 0.14 12.8 0.0 0.53 10.9 0.0 2.0 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SOR_SNZ PF01680.17 EGG05644.1 - 1.8e-109 364.3 4.6 2.4e-109 363.9 4.6 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EGG05644.1 - 4.3e-11 42.6 5.3 8.5e-08 31.8 0.2 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EGG05644.1 - 1.7e-07 30.6 0.9 0.00035 19.8 0.0 2.9 2 2 1 3 3 3 2 Dihydrouridine synthase (Dus) NMO PF03060.15 EGG05644.1 - 0.00044 19.7 2.5 0.016 14.6 0.0 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase NanE PF04131.14 EGG05644.1 - 0.00062 19.0 0.1 0.05 12.8 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 EGG05644.1 - 0.002 17.6 0.1 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein TetR_C_27 PF17935.1 EGG05644.1 - 0.0043 17.1 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 EGG05644.1 - 0.0062 15.7 0.0 0.089 11.9 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.18 EGG05644.1 - 0.022 13.8 0.6 0.057 12.4 0.0 2.0 2 1 1 3 3 3 0 FMN-dependent dehydrogenase HSP70 PF00012.20 EGG05645.1 - 8.4e-260 863.1 3.3 9.5e-260 862.9 3.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGG05645.1 - 7.6e-15 54.5 0.1 1.1e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGG05645.1 - 0.0047 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Radial_spoke_3 PF06098.11 EGG05645.1 - 0.029 13.7 1.2 0.049 12.9 1.2 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 Hydantoinase_A PF01968.18 EGG05645.1 - 0.039 13.2 0.1 0.095 11.9 0.1 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EGG05645.1 - 0.046 13.2 0.0 4.6 6.7 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family CxC5 PF18718.1 EGG05647.1 - 2e-30 105.3 7.0 2.9e-30 104.7 7.0 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases COMP PF11598.8 EGG05647.1 - 0.024 15.1 0.1 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Pkinase PF00069.25 EGG05648.1 - 6e-23 81.5 0.0 1.2e-22 80.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG05648.1 - 2e-13 50.3 0.0 9.8e-13 48.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase OPT PF03169.15 EGG05649.1 - 1.2e-93 314.9 30.2 6.8e-93 312.4 30.2 1.8 1 1 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 EGG05650.1 - 2.7e-78 264.1 29.9 4.6e-57 194.0 14.4 3.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein DUF3265 PF11665.8 EGG05650.1 - 0.16 12.2 1.2 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3265) GATase_2 PF00310.21 EGG05651.1 - 4.9e-177 588.8 0.0 6.6e-177 588.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EGG05651.1 - 7.1e-156 519.0 0.0 1.2e-155 518.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EGG05651.1 - 6e-113 377.0 0.0 8.2e-112 373.2 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EGG05651.1 - 1.4e-86 289.0 3.8 2.2e-86 288.3 3.8 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EGG05651.1 - 1.2e-22 80.5 0.0 2.2e-16 59.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EGG05651.1 - 1.2e-21 76.6 0.1 3.3e-21 75.2 0.1 1.8 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 EGG05651.1 - 2.9e-07 30.6 0.0 1.3e-06 28.5 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGG05651.1 - 4.5e-07 30.3 0.0 0.00055 20.4 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGG05651.1 - 8e-07 29.0 0.1 0.0033 17.1 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG05651.1 - 8.1e-05 21.5 0.7 0.00016 20.5 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGG05651.1 - 0.00038 19.8 1.3 0.014 14.7 0.0 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGG05651.1 - 0.00052 19.4 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EGG05651.1 - 0.002 17.3 0.1 0.0076 15.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EGG05651.1 - 0.0063 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGG05651.1 - 0.0094 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EGG05651.1 - 0.011 15.1 0.4 0.036 13.4 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EGG05651.1 - 0.013 15.9 3.2 2.3 8.7 0.1 3.3 4 0 0 4 4 3 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EGG05651.1 - 0.017 14.4 0.0 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.18 EGG05651.1 - 0.022 13.8 0.7 0.11 11.5 1.1 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Thi4 PF01946.17 EGG05651.1 - 0.035 13.4 0.1 0.079 12.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family AdoHcyase_NAD PF00670.21 EGG05651.1 - 0.049 13.7 0.2 12 5.9 0.0 2.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NDUFA12 PF05071.16 EGG05652.1 - 8.6e-10 39.3 1.5 3.3e-09 37.4 1.5 2.0 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Thioredoxin PF00085.20 EGG05652.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Tau95 PF09734.9 EGG05653.1 - 4.3e-29 102.1 0.2 9.9e-29 100.9 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain RAP-1 PF03085.15 EGG05653.1 - 0.014 15.1 0.2 0.67 9.6 0.0 2.2 1 1 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) OPT PF03169.15 EGG05654.1 - 7.4e-65 219.8 26.9 7.5e-64 216.4 26.9 2.4 1 1 0 1 1 1 1 OPT oligopeptide transporter protein CDtoxinA PF03498.14 EGG05654.1 - 0.2 11.3 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain Cyto_heme_lyase PF01265.17 EGG05658.1 - 2.9e-44 151.8 8.2 8.2e-44 150.3 8.2 1.8 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase GAGA PF09237.11 EGG05658.1 - 0.12 12.2 1.0 1 9.2 0.3 2.2 2 0 0 2 2 2 0 GAGA factor zf-CHY PF05495.12 EGG05659.1 - 5.3e-14 52.5 10.2 1.1e-13 51.4 10.2 1.5 1 1 0 1 1 1 1 CHY zinc finger zinc_ribbon_4 PF13717.6 EGG05659.1 - 0.0065 16.4 7.1 0.82 9.6 3.4 2.9 2 1 0 2 2 2 2 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EGG05659.1 - 0.0097 16.0 1.9 0.0097 16.0 1.9 2.6 2 1 0 2 2 2 1 Zinc ribbon domain Cys_rich_KTR PF14205.6 EGG05659.1 - 0.029 14.2 5.1 1.6 8.6 0.1 2.5 1 1 1 2 2 2 0 Cysteine-rich KTR HypA PF01155.19 EGG05659.1 - 0.058 13.4 0.9 0.058 13.4 0.9 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NOB1_Zn_bind PF08772.11 EGG05659.1 - 0.061 13.5 0.3 0.061 13.5 0.3 1.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-UDP PF14569.6 EGG05659.1 - 0.11 12.7 6.7 0.12 12.5 4.6 2.0 1 1 1 2 2 2 0 Zinc-binding RING-finger Anti-TRAP PF15777.5 EGG05659.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.3 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF3909 PF13077.6 EGG05659.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) Zn_Tnp_IS1595 PF12760.7 EGG05659.1 - 0.39 10.7 10.2 4.2 7.4 0.1 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF3797 PF12677.7 EGG05659.1 - 0.97 9.4 0.1 0.97 9.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) zf-H2C2_2 PF13465.6 EGG05659.1 - 1.9 9.0 7.3 12 6.5 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zinc_ribbon_9 PF14369.6 EGG05659.1 - 3.9 7.8 12.4 0.99 9.7 3.6 3.0 2 1 1 3 3 3 0 zinc-ribbon zf-LITAF-like PF10601.9 EGG05659.1 - 7.9 6.8 11.7 2.2e+02 2.2 11.0 3.0 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain Sporozoite_P67 PF05642.11 EGG05660.1 - 0.029 12.5 0.6 0.044 11.9 0.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen E1_dh PF00676.20 EGG05661.1 - 1.1e-111 372.6 0.0 1.5e-111 372.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EGG05661.1 - 0.013 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase LRR_4 PF12799.7 EGG05662.1 - 1.3 9.5 12.8 13 6.3 0.3 4.7 3 2 0 4 4 4 0 Leucine Rich repeats (2 copies) Mgm101p PF06420.12 EGG05663.1 - 2.9e-76 254.7 0.0 4e-76 254.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 7TMR-HDED PF07697.11 EGG05664.1 - 0.081 13.0 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 7TM-HD extracellular DUF3144 PF11342.8 EGG05664.1 - 0.11 12.8 0.6 0.23 11.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3144) Cupin_8 PF13621.6 EGG05665.1 - 3e-15 56.6 0.0 1.1e-11 45.0 0.0 2.2 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 EGG05665.1 - 0.00025 21.4 0.3 0.00099 19.5 0.2 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Retro_M PF02813.14 EGG05665.1 - 0.19 12.2 0.0 0.56 10.6 0.0 1.7 1 1 0 1 1 1 0 Retroviral M domain B12D PF06522.11 EGG05666.1 - 9.7e-22 76.6 0.2 1.1e-21 76.4 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit CxC5 PF18718.1 EGG05667.1 - 9.9e-31 106.3 4.7 1.4e-30 105.8 4.7 1.2 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases SCHIP-1 PF10148.9 EGG05672.1 - 1.1 8.9 3.3 0.44 10.1 0.4 1.7 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 Chromo PF00385.24 EGG05675.1 - 0.00039 20.3 1.4 0.00039 20.3 1.4 2.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Nit_Regul_Hom PF10126.9 EGG05675.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII DUF726 PF05277.12 EGG05676.1 - 7.7e-79 265.1 0.1 1e-78 264.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Hydrolase_4 PF12146.8 EGG05676.1 - 0.0021 17.4 0.0 0.0037 16.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 EGG05676.1 - 0.0054 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 EGG05676.1 - 0.0099 15.4 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 EGG05676.1 - 0.019 14.7 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 EGG05676.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain MRP-S25 PF13741.6 EGG05677.1 - 3e-19 69.5 0.5 3.7e-19 69.2 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 DUF3807 PF12720.7 EGG05678.1 - 0.61 10.3 7.6 1.2 9.4 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Codanin-1_C PF15296.6 EGG05681.1 - 1.4 9.0 4.7 1.7 8.8 0.0 2.8 3 0 0 3 3 3 0 Codanin-1 C-terminus MarB PF13999.6 EGG05682.1 - 0.012 15.4 0.6 0.045 13.6 0.7 1.9 2 0 0 2 2 2 0 MarB protein YdfZ PF14001.6 EGG05682.1 - 0.21 12.0 0.0 0.46 10.9 0.0 1.5 1 0 0 1 1 1 0 YdfZ protein DnaJ PF00226.31 EGG05686.1 - 4.1e-10 39.6 0.0 4.4e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 DnaJ domain Secretin PF00263.21 EGG05690.1 - 0.0049 16.5 4.1 0.0065 16.1 4.1 1.3 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Porin_10 PF14121.6 EGG05690.1 - 0.012 14.3 0.5 0.011 14.4 0.5 1.0 1 0 0 1 1 1 0 Putative porin Porin_3 PF01459.22 EGG05690.1 - 0.014 14.9 0.6 0.021 14.3 0.6 1.5 1 1 0 1 1 1 0 Eukaryotic porin DUF1943 PF09172.11 EGG05690.1 - 0.019 14.2 1.1 0.029 13.6 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF4364 PF14277.6 EGG05690.1 - 0.023 14.5 1.0 0.052 13.3 0.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4364) DBB PF14545.6 EGG05690.1 - 0.053 13.4 4.0 0.077 12.9 4.0 1.2 1 0 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, LEA_2 PF03168.13 EGG05690.1 - 0.059 13.9 5.3 0.28 11.7 3.9 2.2 1 1 1 2 2 2 0 Late embryogenesis abundant protein AMP-binding_C_2 PF14535.6 EGG05690.1 - 0.69 10.3 8.4 6.4 7.2 8.3 2.3 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Glyco_hydro_2 PF00703.21 EGG05690.1 - 1.2 9.8 5.8 19 6.0 5.9 2.2 1 1 0 1 1 1 0 Glycosyl hydrolases family 2 VWD PF00094.25 EGG05690.1 - 2.2 8.5 7.0 4.2 7.6 7.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type D domain Sds3 PF08598.11 EGG05691.1 - 0.011 15.7 4.8 0.011 15.7 4.8 1.9 2 0 0 2 2 2 0 Sds3-like HTH_21 PF13276.6 EGG05691.1 - 0.27 11.4 1.8 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 HTH-like domain IR1-M PF12185.8 EGG05693.1 - 0.019 14.9 0.1 0.071 13.1 0.1 1.9 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain HIRAN PF08797.11 EGG05693.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain Fusion_gly PF00523.18 EGG05693.1 - 0.097 10.9 0.2 0.15 10.3 0.2 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Calc_CGRP_IAPP PF00214.19 EGG05693.1 - 0.49 10.8 2.8 0.99 9.8 0.3 2.6 1 1 1 2 2 2 0 Calcitonin / CGRP / IAPP family TPT PF03151.16 EGG05698.1 - 2.9e-21 76.1 17.8 3.9e-21 75.6 17.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family TPR_2 PF07719.17 EGG05699.1 - 6.5e-25 85.2 15.9 0.00055 19.8 0.1 12.4 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGG05699.1 - 2.1e-23 81.0 3.0 0.0027 18.0 0.1 12.0 13 1 1 14 14 13 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGG05699.1 - 1.4e-21 76.8 13.6 1.6e-07 31.9 2.6 7.7 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGG05699.1 - 2e-21 74.9 7.5 0.0012 18.6 0.1 10.2 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGG05699.1 - 1.5e-16 59.7 16.2 0.0029 18.3 0.0 9.8 8 3 2 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGG05699.1 - 1.7e-16 59.6 9.1 0.00011 21.8 0.1 7.4 7 1 1 8 8 8 4 TPR repeat TPR_12 PF13424.6 EGG05699.1 - 4.9e-15 55.6 16.5 0.16 12.3 0.0 9.5 8 2 1 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGG05699.1 - 1.4e-13 49.9 20.4 0.0024 17.9 0.0 10.9 14 0 0 14 14 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG05699.1 - 7.6e-08 32.8 17.3 2.6 8.6 0.3 10.0 6 3 4 10 10 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG05699.1 - 8.2e-08 31.8 7.7 0.84 9.8 0.1 9.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG05699.1 - 3.2e-07 30.4 8.5 0.029 14.5 1.1 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.17 EGG05699.1 - 1.6e-05 25.4 9.1 0.25 11.8 0.0 4.9 3 1 0 3 3 3 2 Bacterial transcriptional activator domain TPR_6 PF13174.6 EGG05699.1 - 0.0014 19.1 13.3 3.1 8.6 0.0 9.8 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGG05699.1 - 0.0052 16.6 5.5 24 4.9 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat ChAPs PF09295.10 EGG05699.1 - 0.0094 15.0 0.5 4.4 6.2 0.0 4.1 4 0 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_22 PF18833.1 EGG05699.1 - 0.014 15.6 1.7 0.32 11.1 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4795 PF16043.5 EGG05699.1 - 0.019 14.6 4.2 0.14 11.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) PriC PF07445.12 EGG05699.1 - 0.062 13.2 3.3 0.23 11.4 1.6 2.7 2 0 0 2 2 2 0 Primosomal replication protein priC Peptidase_C30 PF05409.13 EGG05699.1 - 0.087 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 DUF4919 PF16266.5 EGG05699.1 - 0.3 11.0 1.7 0.66 9.9 0.0 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4919) HemY_N PF07219.13 EGG05699.1 - 1.9 8.7 4.2 39 4.5 0.0 4.4 4 0 0 4 4 4 0 HemY protein N-terminus ANAPC3 PF12895.7 EGG05699.1 - 2.3 8.5 14.5 7.6 6.8 0.3 5.6 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Sec7 PF01369.20 EGG05700.1 - 5.3e-65 218.5 0.0 1.1e-64 217.5 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EGG05700.1 - 1.6e-17 63.9 1.2 2.7e-16 59.9 0.0 3.4 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGG05700.1 - 0.05 13.5 0.3 3.2 7.7 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) F-box-like PF12937.7 EGG05701.1 - 0.00063 19.6 0.2 0.0012 18.7 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG05701.1 - 0.055 13.4 1.7 0.12 12.3 0.2 2.2 2 0 0 2 2 2 0 F-box domain DUF267 PF03268.14 EGG05701.1 - 0.12 11.2 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 MFS_1 PF07690.16 EGG05702.1 - 2.4e-28 99.1 28.6 3.1e-28 98.7 28.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily QCR10 PF09796.9 EGG05703.1 - 1.4e-24 85.9 0.0 1.7e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.10 EGG05703.1 - 0.065 13.2 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein LRR_4 PF12799.7 EGG05705.1 - 7.3 7.2 8.4 1.7e+02 2.8 0.0 5.1 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) ECH_1 PF00378.20 EGG05706.1 - 1.5e-14 53.9 0.5 2.5e-14 53.2 0.5 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_C PF02911.18 EGG05706.1 - 0.00082 19.6 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Formyl_trans_N PF00551.19 EGG05706.1 - 0.012 15.4 0.0 0.18 11.5 0.0 2.5 1 1 0 1 1 1 0 Formyl transferase Cu-oxidase PF00394.22 EGG05707.1 - 7.8e-29 100.8 0.2 1e-26 94.0 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGG05707.1 - 2.3e-27 95.4 0.9 6e-27 94.0 0.2 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG05707.1 - 2.3e-25 88.9 4.6 5e-21 74.9 0.9 4.7 3 2 0 3 3 3 2 Multicopper oxidase SoxE PF06525.11 EGG05707.1 - 0.033 13.7 0.0 0.42 10.1 0.0 2.4 2 0 0 2 2 2 0 Sulfocyanin (SoxE) domain Pkinase PF00069.25 EGG05709.1 - 1.4e-48 165.6 0.0 2.7e-48 164.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG05709.1 - 3.2e-23 82.3 0.0 1.3e-22 80.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase SPOC PF07744.13 EGG05709.1 - 0.071 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 SPOC domain DUF5580 PF17743.1 EGG05710.1 - 0.32 9.5 7.9 0.14 10.6 5.3 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5580) Tannase PF07519.11 EGG05711.1 - 4.8e-74 250.0 0.0 6.5e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase UPF0113_N PF17833.1 EGG05712.1 - 4.9e-30 103.9 0.5 7.2e-30 103.4 0.5 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EGG05712.1 - 4.7e-26 90.9 0.0 7.6e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 EGG05712.1 - 0.00061 19.8 0.1 0.0013 18.7 0.1 1.7 1 1 0 1 1 1 1 Phloem filament protein PP1 cystatin-like domain Dynein_light PF01221.18 EGG05713.1 - 7.4e-37 125.6 0.2 8.3e-37 125.4 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 TPR_2 PF07719.17 EGG05714.1 - 1.4e-19 68.5 2.1 3.2e-06 26.8 0.0 4.6 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGG05714.1 - 4.3e-17 61.5 3.5 5.5e-05 22.8 0.1 4.2 2 2 2 4 4 4 3 TPR repeat TPR_1 PF00515.28 EGG05714.1 - 2.4e-16 58.8 5.4 2.8e-06 26.9 0.0 4.9 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG05714.1 - 3.5e-12 46.6 0.1 3.2e-05 24.3 0.5 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG05714.1 - 3.7e-11 42.6 2.5 0.00092 19.4 0.1 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG05714.1 - 4.9e-11 42.8 2.3 8.3e-05 22.8 0.0 3.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG05714.1 - 1.3e-09 37.5 5.1 0.0014 18.6 0.1 4.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG05714.1 - 4.5e-09 36.4 0.0 0.027 15.3 0.0 3.9 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG05714.1 - 3.3e-08 34.0 0.0 0.0071 17.0 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGG05714.1 - 2e-06 27.5 5.6 0.0027 17.5 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG05714.1 - 2.1e-05 24.7 0.0 0.058 13.6 0.0 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGG05714.1 - 0.0002 21.8 0.1 3 8.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGG05714.1 - 0.00026 20.3 0.1 0.00037 19.8 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.18 EGG05714.1 - 0.0011 19.0 2.1 6.3 6.9 0.0 3.8 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 EGG05714.1 - 0.0025 18.1 1.1 0.013 15.8 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG05714.1 - 0.0054 16.9 0.0 1.2 9.4 0.0 2.6 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG05714.1 - 0.023 14.7 0.5 21 5.4 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.8 EGG05714.1 - 0.04 12.8 0.3 1.8 7.4 0.1 2.0 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 BTAD PF03704.17 EGG05714.1 - 0.053 14.0 0.1 0.29 11.6 0.1 1.9 2 0 0 2 2 2 0 Bacterial transcriptional activator domain Sel1 PF08238.12 EGG05714.1 - 0.1 13.3 0.1 6 7.7 0.0 3.2 4 0 0 4 4 4 0 Sel1 repeat PIEZO PF15917.5 EGG05716.1 - 0.085 12.3 3.6 0.11 12.0 3.6 1.1 1 0 0 1 1 1 0 Piezo CDC45 PF02724.14 EGG05716.1 - 0.71 8.1 6.3 0.79 7.9 6.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.16 EGG05716.1 - 1.7 8.1 6.5 2 7.9 6.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 OAD_gamma PF04277.13 EGG05716.1 - 1.8 9.2 5.5 2.7 8.6 5.5 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Presenilin PF01080.17 EGG05716.1 - 8.5 5.0 7.0 9.4 4.9 7.0 1.0 1 0 0 1 1 1 0 Presenilin zf-C2H2 PF00096.26 EGG05720.1 - 9.6e-11 41.5 12.7 2.5e-05 24.5 2.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG05720.1 - 3.6e-09 36.7 16.6 1.7e-06 28.2 2.5 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG05720.1 - 3.4e-06 27.4 12.5 0.013 16.3 2.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-MYST PF17772.1 EGG05720.1 - 0.0059 16.2 0.2 0.034 13.8 0.0 2.3 2 0 0 2 2 2 1 MYST family zinc finger domain zf_UBZ PF18439.1 EGG05720.1 - 0.055 13.1 3.2 0.79 9.4 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_ribbon_SprT PF17283.2 EGG05720.1 - 0.11 12.4 2.5 0.26 11.2 2.5 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain GAGA PF09237.11 EGG05720.1 - 0.13 12.1 1.2 0.34 10.7 1.2 1.7 1 0 0 1 1 1 0 GAGA factor zf-C2H2_3rep PF18868.1 EGG05720.1 - 0.21 12.3 3.0 1.1 9.9 0.2 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 EGG05720.1 - 0.69 10.1 3.7 1.9 8.7 3.7 1.8 1 1 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 EGG05720.1 - 0.95 9.5 5.0 0.5 10.4 2.6 1.7 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_6 PF13912.6 EGG05720.1 - 1.4 9.0 9.3 0.64 10.1 1.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 EGG05720.1 - 1.5 8.9 7.6 2 8.5 2.1 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.8 EGG05720.1 - 1.9 8.9 6.2 9.1 6.7 0.5 2.5 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EGG05720.1 - 2.2 8.1 7.0 0.15 11.9 0.8 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Aldedh PF00171.22 EGG05721.1 - 9.1e-122 406.9 0.0 1e-121 406.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGG05721.1 - 0.00058 19.0 0.0 0.015 14.4 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) Zn_clus PF00172.18 EGG05723.1 - 0.6 10.3 7.1 3.5 7.8 2.0 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.31 EGG05724.1 - 8e-08 32.3 0.0 2.5e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 EGG05724.1 - 1e-07 32.3 0.6 0.05 14.1 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG05724.1 - 3.7e-06 27.1 3.0 1.5 9.2 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGG05724.1 - 0.0021 18.6 0.5 30 5.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGG05724.1 - 0.0031 17.6 0.7 32 5.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG05724.1 - 0.0038 17.4 4.3 6.8 7.0 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGG05724.1 - 0.0044 16.9 1.6 4 7.7 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat SPO22 PF08631.10 EGG05724.1 - 0.029 13.9 2.3 0.042 13.3 1.8 1.5 1 1 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.6 EGG05724.1 - 0.1 13.5 1.6 14 6.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Pentaxin PF00354.17 EGG05725.1 - 0.009 15.7 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 Pentaxin family UvrB_inter PF17757.1 EGG05726.1 - 0.027 14.6 0.0 0.11 12.6 0.0 2.1 1 1 0 1 1 1 0 UvrB interaction domain CAMSAP_CC1 PF17095.5 EGG05726.1 - 0.24 11.3 3.7 2.2 8.2 0.9 2.9 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin DUF2730 PF10805.8 EGG05726.1 - 0.44 10.6 9.2 0.46 10.6 2.6 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) LPP PF04728.13 EGG05726.1 - 3 8.3 6.2 2.9 8.3 0.3 4.1 4 0 0 4 4 4 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 EGG05726.1 - 3.8 8.0 13.3 19 5.8 0.8 5.7 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Zn_clus PF00172.18 EGG05727.1 - 6.1e-05 23.1 13.1 0.00011 22.2 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VCX_VCY PF15231.6 EGG05727.1 - 0.017 15.8 0.6 0.038 14.7 0.6 1.5 1 0 0 1 1 1 0 Variable charge X/Y family DUF3287 PF11690.8 EGG05727.1 - 0.025 14.3 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) ABC_tran_CTD PF16326.5 EGG05727.1 - 0.56 10.5 3.6 0.81 10.0 1.4 2.3 2 1 0 2 2 2 0 ABC transporter C-terminal domain Tmemb_14 PF03647.13 EGG05728.1 - 1.3e-18 67.5 5.8 1.5e-18 67.3 5.8 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF3188 PF11384.8 EGG05728.1 - 2.6 7.8 8.6 0.4 10.4 1.3 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3188) SWIB PF02201.18 EGG05731.1 - 0.12 12.3 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 SWIB/MDM2 domain Nucleopor_Nup85 PF07575.13 EGG05732.1 - 0.069 11.7 0.0 0.081 11.5 0.0 1.0 1 0 0 1 1 1 0 Nup85 Nucleoporin OPT PF03169.15 EGG05733.1 - 8.4e-110 368.2 39.4 9.7e-110 368.0 39.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Apolipoprotein PF01442.18 EGG05734.1 - 0.00021 21.2 43.0 0.00021 21.2 43.0 5.2 1 1 4 5 5 5 4 Apolipoprotein A1/A4/E domain Filament PF00038.21 EGG05734.1 - 0.87 9.1 124.9 1.5 8.3 34.3 6.6 1 1 3 6 6 6 0 Intermediate filament protein DSHCT PF08148.12 EGG05735.1 - 6.7e-49 165.7 0.8 1.7e-48 164.4 0.1 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EGG05735.1 - 1.9e-38 131.3 0.1 3.7e-38 130.4 0.1 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EGG05735.1 - 1.3e-26 94.1 0.0 2.2e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EGG05735.1 - 7.5e-18 64.9 0.0 1.5e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGG05735.1 - 1.5e-06 28.3 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGG05735.1 - 1.9e-05 25.0 0.1 7.4e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3516 PF12029.8 EGG05735.1 - 0.0022 17.2 0.4 0.0022 17.2 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3516) Nexin_C PF08628.12 EGG05736.1 - 0.064 13.8 0.1 0.13 12.8 0.1 1.6 1 0 0 1 1 1 0 Sorting nexin C terminal Laminin_II PF06009.12 EGG05736.1 - 0.1 12.6 1.6 0.73 9.9 1.4 2.2 1 1 1 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 EGG05736.1 - 0.2 12.1 0.3 2.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 EGG05736.1 - 0.23 11.9 3.7 12 6.3 0.9 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Dad3 PF08656.10 EGG05736.1 - 0.69 10.0 2.4 3.9 7.6 2.4 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad3 Matrilin_ccoil PF10393.9 EGG05736.1 - 1.5 8.7 3.6 13 5.7 0.2 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Phage_TAC_4 PF08748.11 EGG05737.1 - 0.18 12.1 0.1 0.18 12.1 0.1 1.8 2 0 0 2 2 2 0 Phage tail assembly chaperone LigB PF02900.18 EGG05738.1 - 1.6e-35 122.5 0.0 1.9e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Macoilin PF09726.9 EGG05739.1 - 8.6 4.8 11.4 12 4.3 11.4 1.3 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 EGG05739.1 - 8.9 5.0 8.9 9.7 4.8 8.9 1.2 1 0 0 1 1 1 0 Presenilin DUF3294 PF07957.11 EGG05741.1 - 0.0011 18.8 2.2 0.18 11.5 0.0 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF3294) MIP PF00230.20 EGG05742.1 - 4.3e-45 154.2 18.6 5e-45 154.0 18.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein Pkr1 PF08636.10 EGG05742.1 - 3.2 8.0 8.6 0.98 9.6 4.5 2.2 2 0 0 2 2 2 0 ER protein Pkr1 Glyco_hydro81C PF17652.1 EGG05744.1 - 1.6e-105 353.2 0.0 2.1e-105 352.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EGG05744.1 - 9.6e-58 195.9 0.1 1.3e-57 195.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain TPR_MLP1_2 PF07926.12 EGG05745.1 - 8.1e-05 22.7 14.0 8.1e-05 22.7 14.0 15.4 1 1 12 14 14 14 5 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EGG05745.1 - 0.0014 17.6 29.9 0.0014 17.6 29.9 10.9 1 1 10 11 11 11 7 Spc7 kinetochore protein DUF4743 PF15916.5 EGG05745.1 - 0.72 9.8 4.2 13 5.8 0.4 3.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4743) TMEM191C PF15194.6 EGG05745.1 - 9.5 6.4 8.3 13 6.0 0.2 3.8 3 0 0 3 3 3 0 TMEM191C family WD40 PF00400.32 EGG05746.1 - 5.2e-07 30.3 8.8 0.31 12.0 0.1 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat SRA1 PF07304.11 EGG05746.1 - 8.2e-05 22.4 0.0 0.00031 20.6 0.0 2.0 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 EGG05746.1 - 0.00099 19.2 0.6 0.0024 17.9 0.0 1.9 2 0 0 2 2 2 1 Prp18 domain Sec16_C PF12931.7 EGG05746.1 - 0.012 15.3 0.6 0.036 13.7 0.6 1.9 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 KORA PF16509.5 EGG05746.1 - 0.17 12.2 0.0 0.48 10.7 0.0 1.7 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor WD40 PF00400.32 EGG05747.1 - 3.6e-13 49.8 0.4 3e-08 34.2 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.8 EGG05747.1 - 0.0044 15.7 0.0 0.0044 15.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Retrotran_gag_2 PF14223.6 EGG05749.1 - 8.8e-07 28.7 0.4 1.6e-06 27.8 0.4 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGG05749.1 - 0.1 12.4 0.3 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF747 PF05346.11 EGG05753.1 - 2.8e-99 332.6 0.8 3.9e-99 332.1 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family LSM PF01423.22 EGG05753.1 - 1.5e-18 66.2 0.2 2.9e-18 65.3 0.2 1.5 1 0 0 1 1 1 1 LSM domain AAA_12 PF13087.6 EGG05755.1 - 7.6e-48 162.8 0.0 1.2e-47 162.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGG05755.1 - 2e-28 99.9 0.0 8.5e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EGG05755.1 - 9.8e-15 54.8 0.0 2.9e-14 53.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG05755.1 - 1e-10 42.1 0.0 3.8e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain zf-met PF12874.7 EGG05755.1 - 5.9e-07 29.7 2.4 2.4e-05 24.6 1.1 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type UvrD-helicase PF00580.21 EGG05755.1 - 2e-06 27.6 0.0 0.00069 19.2 0.0 2.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 EGG05755.1 - 8.7e-05 22.6 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EGG05755.1 - 0.0011 18.5 0.0 0.062 12.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 EGG05755.1 - 0.0033 17.2 0.0 0.0097 15.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGG05755.1 - 0.0035 17.6 0.0 0.01 16.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain zf-C2H2_jaz PF12171.8 EGG05755.1 - 0.0036 17.5 3.9 0.0062 16.8 1.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Helicase_RecD PF05127.14 EGG05755.1 - 0.0038 17.1 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.6 EGG05755.1 - 0.018 15.4 0.0 0.081 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 EGG05755.1 - 0.021 15.2 0.0 0.21 12.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-U1 PF06220.12 EGG05755.1 - 0.057 13.2 1.0 0.18 11.6 0.2 2.2 2 0 0 2 2 2 0 U1 zinc finger UvrD_C_2 PF13538.6 EGG05755.1 - 0.062 13.1 0.2 0.23 11.3 0.2 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AKAP95 PF04988.12 EGG05755.1 - 0.081 13.2 1.4 13 6.0 0.6 2.3 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) T2SSE PF00437.20 EGG05755.1 - 0.087 11.9 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C PF13361.6 EGG05755.1 - 0.11 11.9 0.0 13 5.1 0.0 2.5 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain ATPase_2 PF01637.18 EGG05755.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 EGG05755.1 - 0.14 11.3 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 EGG05755.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Phage_connector PF05352.12 EGG05755.1 - 0.16 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Phage Connector (GP10) zf-DBF PF07535.12 EGG05755.1 - 0.17 12.1 1.8 18 5.5 0.3 2.7 2 0 0 2 2 2 0 DBF zinc finger PIF1 PF05970.14 EGG05755.1 - 0.23 10.6 0.0 14 4.7 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase SGL PF08450.12 EGG05756.1 - 0.028 14.0 0.0 4 7.0 0.0 2.4 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region W_rich_C PF07483.11 EGG05758.1 - 0.037 14.2 0.1 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain FBA_3 PF08268.12 EGG05758.1 - 0.1 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 F-box associated domain DUF2781 PF10914.8 EGG05759.1 - 4.9e-19 69.2 2.6 9.3e-19 68.3 2.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) DUF2628 PF10947.8 EGG05759.1 - 0.98 9.8 5.6 1.4 9.3 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) HSP20 PF00011.21 EGG05760.1 - 4e-21 75.1 0.2 4.9e-21 74.8 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG05760.1 - 1e-06 28.2 0.0 1.7e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Coatomer_E PF04733.14 EGG05763.1 - 8.1e-43 146.9 0.5 9.9e-43 146.6 0.5 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EGG05763.1 - 4.1e-08 33.6 5.3 0.01 16.3 0.2 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG05763.1 - 4.9e-07 29.9 0.7 9e-05 22.6 0.0 3.7 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EGG05763.1 - 1.5e-05 25.4 1.5 0.55 11.2 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG05763.1 - 9.3e-05 22.3 0.1 0.029 14.5 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG05763.1 - 0.0019 18.0 0.1 0.048 13.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG05763.1 - 0.0026 17.8 0.0 0.39 11.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG05763.1 - 0.058 13.7 1.5 22 5.4 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGG05763.1 - 0.12 13.0 0.3 3.3 8.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-AN1 PF01428.16 EGG05764.1 - 5.7 7.2 10.1 0.14 12.4 1.7 2.5 2 1 0 2 2 2 0 AN1-like Zinc finger Prenyltransf PF01255.19 EGG05767.1 - 9.5e-71 237.9 0.0 1.2e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase zf-C2H2 PF00096.26 EGG05770.1 - 2.4e-10 40.3 8.1 0.00063 20.1 0.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG05770.1 - 3.2e-07 30.5 2.5 0.014 15.8 0.0 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG05770.1 - 3.3e-06 27.4 8.0 0.22 12.4 0.0 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EGG05770.1 - 0.0072 16.6 2.1 0.022 15.0 0.8 2.4 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 EGG05770.1 - 0.0074 16.3 3.1 0.2 11.7 0.1 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EGG05770.1 - 0.4 10.8 1.6 0.94 9.6 0.1 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger Promethin PF16015.5 EGG05771.1 - 1.9e-06 27.7 2.9 2.1e-06 27.6 2.9 1.1 1 0 0 1 1 1 1 Promethin Aldo_ket_red PF00248.21 EGG05772.1 - 3.8e-40 137.9 0.2 7.6e-34 117.2 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Retrotran_gag_2 PF14223.6 EGG05773.1 - 4e-13 49.2 0.0 4.7e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type LIAS_N PF16881.5 EGG05774.1 - 1.6e-20 73.5 0.1 4.7e-20 72.0 0.1 1.8 1 1 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EGG05774.1 - 6.5e-11 42.9 0.0 1.6e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily DRMBL PF07522.14 EGG05775.1 - 0.00024 21.3 0.3 0.0015 18.7 0.3 2.4 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EGG05775.1 - 0.0016 18.0 0.0 0.009 15.5 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Plant_NMP1 PF06694.11 EGG05776.1 - 0.13 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) adh_short PF00106.25 EGG05777.1 - 4.7e-17 62.1 0.0 7.1e-17 61.5 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG05777.1 - 2.3e-08 33.9 0.0 3.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG05777.1 - 0.00039 20.4 0.2 0.084 12.8 0.0 2.2 2 0 0 2 2 2 2 KR domain Glyco_hydro_76 PF03663.14 EGG05778.1 - 7.2e-47 160.7 12.8 1.8e-46 159.4 12.8 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGG05778.1 - 0.032 13.3 3.6 0.097 11.7 0.2 2.4 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 PAXNEB PF05625.11 EGG05779.1 - 1e-55 189.4 0.0 2.1e-55 188.4 0.0 1.3 1 1 0 1 1 1 1 PAXNEB protein ATPase PF06745.13 EGG05779.1 - 0.0003 20.2 0.0 0.00069 19.0 0.0 1.6 2 1 0 2 2 2 1 KaiC eIF_4G1 PF12152.8 EGG05779.1 - 0.19 11.9 0.8 0.47 10.7 0.8 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 Glyco_hydro_61 PF03443.14 EGG05780.1 - 1.2e-24 87.4 0.0 2.3e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CFEM PF05730.11 EGG05780.1 - 0.00014 21.9 4.8 0.00014 21.9 4.8 1.8 2 0 0 2 2 2 1 CFEM domain RhoGEF PF00621.20 EGG05781.1 - 2e-36 125.9 0.0 1.6e-35 123.0 0.0 2.4 1 1 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.7 EGG05781.1 - 1.9e-05 24.9 0.3 0.099 13.1 0.0 3.0 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Ras PF00071.22 EGG05782.1 - 6.4e-57 191.7 0.0 7.9e-57 191.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG05782.1 - 5.8e-35 120.1 0.0 8.6e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG05782.1 - 4.6e-16 58.8 0.0 5e-15 55.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG05782.1 - 2.5e-05 23.8 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG05782.1 - 0.00034 20.7 0.0 0.00055 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGG05782.1 - 0.0023 18.3 0.1 0.0034 17.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain SSP160 PF06933.11 EGG05782.1 - 0.0041 15.4 6.3 0.0061 14.8 6.3 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 eIF2A PF08662.11 EGG05783.1 - 4e-37 128.0 0.8 1.1e-34 120.0 0.2 3.0 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EGG05783.1 - 0.00019 21.2 0.0 0.00043 20.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.12 EGG05783.1 - 0.0053 14.8 0.3 0.99 7.3 0.0 2.3 2 0 0 2 2 2 2 IKI3 family WD40 PF00400.32 EGG05783.1 - 0.02 15.8 2.3 34 5.5 0.1 4.9 5 1 1 6 6 6 0 WD domain, G-beta repeat HTH_Tnp_Mu_1 PF02316.16 EGG05783.1 - 0.1 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Mu DNA-binding domain Pkinase PF00069.25 EGG05784.1 - 3e-07 30.1 0.0 3.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EGG05784.1 - 1.2e-06 28.3 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGG05784.1 - 2.4e-06 27.1 0.0 7.7e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EGG05784.1 - 9.6e-05 21.8 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG05784.1 - 0.00039 20.4 0.0 0.0088 16.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGG05784.1 - 0.00059 19.2 0.1 0.0012 18.3 0.1 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_fungal PF17667.1 EGG05784.1 - 0.037 12.8 0.1 0.06 12.1 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EGG05785.1 - 3.8e-46 157.6 0.0 4.4e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG05785.1 - 2.5e-26 92.5 0.0 3.3e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG05785.1 - 0.00011 22.2 0.1 0.0089 16.0 0.0 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG05785.1 - 0.0015 17.5 0.0 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EGG05785.1 - 0.0054 16.4 0.0 0.63 9.6 0.0 2.1 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGG05785.1 - 0.032 13.0 0.0 0.41 9.4 0.0 1.9 1 1 0 2 2 2 0 Fungal protein kinase Fer4_NifH PF00142.18 EGG05785.1 - 0.065 12.7 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Kinase-like PF14531.6 EGG05785.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.5 2 0 0 2 2 2 0 Kinase-like DSPc PF00782.20 EGG05788.1 - 4.1e-24 84.9 0.0 4e-14 52.6 0.0 3.7 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGG05788.1 - 0.022 14.9 0.1 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 EGG05788.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PGAP1 PF07819.13 EGG05789.1 - 5.1e-78 261.9 0.0 8.4e-78 261.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EGG05789.1 - 0.0011 19.6 0.0 0.0021 18.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EGG05789.1 - 0.0096 15.8 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 2 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 EGG05789.1 - 0.044 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 EGG05789.1 - 0.045 13.2 0.1 0.091 12.3 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 EGG05789.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2564 PF10819.8 EGG05792.1 - 0.086 13.2 0.2 0.27 11.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) zf-C2H2 PF00096.26 EGG05793.1 - 0.43 11.1 7.6 0.1 13.1 3.8 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type GPI-anchored PF10342.9 EGG05794.1 - 5.6e-09 36.7 0.0 1.2e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TMEM154 PF15102.6 EGG05794.1 - 0.012 15.5 0.5 0.018 15.0 0.5 1.2 1 0 0 1 1 1 0 TMEM154 protein family Cpn60_TCP1 PF00118.24 EGG05795.1 - 9.8e-153 509.3 6.2 1.1e-152 509.1 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 EGG05795.1 - 0.098 13.1 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Polysacc_deac_1 PF01522.21 EGG05796.1 - 2e-25 89.1 0.0 3.8e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Evf PF18270.1 EGG05796.1 - 0.098 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Virulence factor Evf eIF-4B PF06273.11 EGG05796.1 - 0.28 10.2 0.0 0.45 9.5 0.0 1.3 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Complex1_51K PF01512.17 EGG05797.1 - 2.5e-48 163.8 0.0 3.9e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EGG05797.1 - 8.3e-31 105.9 0.1 1.5e-30 105.1 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EGG05797.1 - 1.8e-07 30.9 0.0 4.5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 EGG05797.1 - 0.047 13.8 0.2 0.087 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) zf-C2H2 PF00096.26 EGG05799.1 - 3e-07 30.5 18.8 2.6e-06 27.6 1.0 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG05799.1 - 5.7e-07 29.7 2.6 5.7e-07 29.7 2.6 3.2 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG05799.1 - 0.00019 22.0 1.0 0.00019 22.0 1.0 3.1 2 1 2 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGG05799.1 - 0.00032 20.9 0.1 0.00032 20.9 0.1 2.4 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG05799.1 - 0.0024 18.2 4.4 0.0038 17.6 0.3 2.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGG05799.1 - 0.016 15.2 1.0 0.016 15.2 1.0 3.1 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 EGG05799.1 - 0.37 11.5 8.9 0.13 12.9 4.7 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain GLTSCR1 PF15249.6 EGG05803.1 - 0.11 13.0 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein LSM PF01423.22 EGG05805.1 - 3.1e-16 58.8 0.2 6.4e-16 57.8 0.2 1.5 1 0 0 1 1 1 1 LSM domain CLU PF13236.6 EGG05808.1 - 3.7e-68 229.7 0.0 6.3e-68 228.9 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGG05808.1 - 9e-44 149.6 1.3 1.6e-43 148.8 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EGG05808.1 - 1.3e-08 35.0 9.3 0.00077 19.7 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGG05808.1 - 5.6e-05 22.9 5.8 1.2 9.1 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF727 PF05303.12 EGG05808.1 - 0.00038 20.5 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) DEAD PF00270.29 EGG05811.1 - 1e-46 158.9 0.0 2.4e-46 157.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG05811.1 - 2.4e-27 95.5 0.1 1.4e-26 93.0 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EGG05811.1 - 9.1e-06 24.7 0.0 0.00041 19.2 0.0 2.8 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 EGG05811.1 - 0.64 10.3 2.7 1.1 9.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 EGG05814.1 - 3.7e-23 82.2 0.0 4.7e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG05814.1 - 2.2e-13 50.1 0.0 2.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_transf_41 PF13844.6 EGG05815.1 - 1.5e-77 261.1 0.8 1.7e-48 165.2 0.0 3.0 2 1 1 3 3 3 3 Glycosyl transferase family 41 NYD-SP28 PF14772.6 EGG05816.1 - 0.15 12.1 1.8 0.7 10.0 0.2 3.0 3 0 0 3 3 3 0 Sperm tail NUDIX PF00293.28 EGG05817.1 - 1.4e-12 47.8 0.0 2.6e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 EGG05817.1 - 2.1e-09 37.9 0.0 7.9e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EGG05817.1 - 0.00018 21.1 1.2 0.0003 20.4 1.2 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Myosin_tail_1 PF01576.19 EGG05817.1 - 0.3 8.9 0.1 0.39 8.4 0.1 1.0 1 0 0 1 1 1 0 Myosin tail CBM_4_9 PF02018.17 EGG05819.1 - 0.00087 19.6 0.1 0.0031 17.8 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate binding domain Alpha-L-AF_C PF06964.12 EGG05819.1 - 0.013 15.6 0.8 0.069 13.3 0.1 2.4 2 1 0 2 2 2 0 Alpha-L-arabinofuranosidase C-terminal domain Ribosomal_S7 PF00177.21 EGG05820.1 - 1.2e-37 128.8 1.6 1.5e-37 128.5 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e COX6B PF02297.17 EGG05821.1 - 3.6e-19 68.8 3.2 4.9e-19 68.4 3.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb GPR15L PF15854.5 EGG05821.1 - 0.054 13.7 0.1 0.088 13.1 0.1 1.4 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 EB1 PF03271.17 EGG05822.1 - 1.2e-13 51.0 0.3 2.8e-13 49.9 0.3 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EGG05822.1 - 4.7e-06 26.7 0.4 1.3e-05 25.3 0.2 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 EGG05822.1 - 0.00023 21.2 0.3 0.00043 20.3 0.3 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein FoP_duplication PF13865.6 EGG05822.1 - 0.093 13.3 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-met2 PF12907.7 EGG05823.1 - 2.8e-08 33.8 2.2 5.9e-08 32.7 2.2 1.6 1 0 0 1 1 1 1 Zinc-binding MMM1 PF10296.9 EGG05824.1 - 4.2e-07 29.3 0.0 4.2e-07 29.3 0.0 2.2 3 0 0 3 3 3 1 Maintenance of mitochondrial morphology protein 1 KDZ PF18758.1 EGG05829.1 - 0.0047 16.6 0.0 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase SEEK1 PF15357.6 EGG05829.1 - 0.11 12.6 0.5 20 5.3 0.0 2.6 2 1 1 3 3 3 0 Psoriasis susceptibility 1 candidate 1 FHA PF00498.26 EGG05830.1 - 3.1e-09 37.1 0.0 5.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF4451 PF14616.6 EGG05830.1 - 0.053 13.7 0.0 0.076 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) PI3_PI4_kinase PF00454.27 EGG05832.1 - 6.2e-33 114.6 0.0 1.1e-23 84.3 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EGG05832.1 - 0.00033 20.4 0.0 0.00094 19.0 0.0 1.8 1 0 0 1 1 1 1 FATC domain Bromo_TP PF07524.13 EGG05834.1 - 0.037 14.0 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Bromodomain associated Nic96 PF04097.14 EGG05836.1 - 4e-21 75.1 0.4 3.5e-19 68.7 0.2 2.0 1 1 1 2 2 2 2 Nup93/Nic96 ANAPC3 PF12895.7 EGG05836.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF5102 PF17104.5 EGG05837.1 - 1.7e-09 38.2 0.8 2.2e-09 37.8 0.8 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF5102) TGT PF01702.18 EGG05837.1 - 0.087 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase RAP1 PF07218.11 EGG05838.1 - 0.0013 17.2 11.8 0.0019 16.6 11.8 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Syntaxin-6_N PF09177.11 EGG05838.1 - 0.0042 17.6 3.5 0.0096 16.5 3.5 1.6 1 0 0 1 1 1 1 Syntaxin 6, N-terminal CASP_C PF08172.12 EGG05838.1 - 0.0093 15.3 7.5 0.017 14.5 7.5 1.3 1 0 0 1 1 1 1 CASP C terminal Tmemb_cc2 PF10267.9 EGG05838.1 - 0.16 11.0 8.5 0.25 10.4 8.5 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein FapA PF03961.13 EGG05838.1 - 0.34 9.5 4.5 0.5 8.9 4.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A GLTP PF08718.11 EGG05838.1 - 0.44 10.8 1.3 0.9 9.8 1.3 1.5 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) DUF948 PF06103.11 EGG05838.1 - 0.58 10.5 1.5 1.4 9.3 1.5 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Neur_chan_memb PF02932.16 EGG05838.1 - 1.5 8.8 5.0 3.1 7.8 5.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.9 EGG05838.1 - 6.3 5.2 10.0 9.4 4.7 10.0 1.1 1 0 0 1 1 1 0 Macoilin family Myb_DNA-binding PF00249.31 EGG05839.1 - 0.00016 21.8 0.1 0.00021 21.4 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain ICL PF00463.21 EGG05840.1 - 1.6e-261 868.4 0.1 1.8e-261 868.2 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EGG05840.1 - 7.6e-09 35.4 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Abhydrolase_1 PF00561.20 EGG05842.1 - 1.9e-06 27.7 0.2 9.8e-06 25.4 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG05842.1 - 2.6e-05 23.6 0.0 0.0017 17.7 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 GARS_A PF01071.19 EGG05843.1 - 4.2e-81 271.4 0.0 6.8e-81 270.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 EGG05843.1 - 2.7e-34 118.6 0.0 6.9e-34 117.2 0.0 1.7 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 EGG05843.1 - 3e-32 111.3 0.9 1.2e-31 109.3 0.0 2.5 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EGG05843.1 - 1e-27 96.2 0.1 2.5e-27 95.0 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EGG05843.1 - 3.6e-15 56.4 1.7 7.8e-15 55.3 1.0 2.0 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 EGG05843.1 - 1.9e-06 27.6 0.0 3.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGG05843.1 - 7.4e-06 26.1 0.0 1.8e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EGG05843.1 - 4e-05 23.2 0.0 7.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 EGG05843.1 - 0.0026 17.4 0.1 0.0046 16.6 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain SIS_2 PF13580.6 EGG05843.1 - 0.0069 16.4 0.2 1.4 9.0 0.0 2.6 2 0 0 2 2 2 1 SIS domain Dala_Dala_lig_C PF07478.13 EGG05843.1 - 0.076 12.5 0.1 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Glyco_hydro_9 PF00759.19 EGG05844.1 - 9.5e-99 331.6 15.6 1.1e-98 331.4 15.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Cu-oxidase_3 PF07732.15 EGG05845.1 - 1.2e-32 112.4 0.3 7.3e-32 109.9 0.2 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EGG05845.1 - 3.5e-31 108.5 0.1 4.1e-30 105.0 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG05845.1 - 1.1e-16 60.8 2.1 1e-09 38.2 0.0 3.8 3 1 0 3 3 3 2 Multicopper oxidase Claudin_3 PF06653.11 EGG05845.1 - 0.37 10.7 1.3 16 5.4 0.3 2.2 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Brix PF04427.18 EGG05846.1 - 2.6e-30 106.0 0.3 3.5e-30 105.6 0.3 1.2 1 0 0 1 1 1 1 Brix domain DUF2517 PF10725.9 EGG05846.1 - 0.0077 16.0 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2517) RHH_1 PF01402.21 EGG05846.1 - 0.11 12.5 0.7 0.25 11.4 0.2 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Metal_resist PF13801.6 EGG05846.1 - 7.7 6.7 7.4 0.22 11.7 1.1 1.6 2 0 0 2 2 2 0 Heavy-metal resistance Mito_carr PF00153.27 EGG05847.1 - 1.2e-29 102.1 6.2 1.1e-13 50.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Fasciclin PF02469.22 EGG05849.1 - 4e-25 88.5 0.3 2.6e-12 47.1 0.1 2.4 2 0 0 2 2 2 2 Fasciclin domain CFEM PF05730.11 EGG05849.1 - 0.1 12.7 4.0 0.2 11.7 4.0 1.5 1 0 0 1 1 1 0 CFEM domain VPS13_mid_rpt PF16910.5 EGG05850.1 - 3.9e-95 317.8 4.4 2.6e-90 302.0 0.4 5.1 5 1 1 6 6 6 2 Repeating coiled region of VPS13 VPS13 PF16908.5 EGG05850.1 - 1.2e-76 257.6 2.6 2.8e-72 243.3 0.2 3.6 3 0 0 3 3 3 3 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 EGG05850.1 - 2.3e-73 246.9 0.7 6.8e-70 235.5 0.0 2.8 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 EGG05850.1 - 9.6e-65 217.7 2.8 2.2e-60 203.5 0.1 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EGG05850.1 - 7.8e-37 125.9 0.1 2.2e-36 124.5 0.1 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EGG05850.1 - 4.8e-08 33.2 0.0 6.5e-06 26.4 0.0 3.2 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain Ribosomal_L32p PF01783.23 EGG05851.1 - 6.6e-16 58.3 3.5 1.1e-15 57.6 3.5 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family Mucin-like PF16058.5 EGG05851.1 - 0.071 13.2 6.3 0.11 12.5 6.3 1.3 1 0 0 1 1 1 0 Mucin-like Exo_endo_phos PF03372.23 EGG05852.1 - 7.5e-16 58.4 0.0 2e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RepB-RCR_reg PF10723.9 EGG05852.1 - 0.081 12.9 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Replication regulatory protein RepB zf-CCHC PF00098.23 EGG05854.1 - 0.18 12.0 0.1 0.29 11.3 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle DASH_Dad4 PF08650.10 EGG05855.1 - 0.14 12.2 1.2 9.9 6.2 0.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad4 SH3_5 PF08460.10 EGG05857.1 - 0.13 12.3 0.0 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain Flavokinase PF01687.17 EGG05858.1 - 0.18 12.1 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Riboflavin kinase Phytochelatin PF05023.14 EGG05860.1 - 0.068 12.4 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Phytochelatin synthase Ribosomal_S26e PF01283.19 EGG05861.1 - 0.016 15.7 0.7 0.17 12.3 0.3 2.1 2 0 0 2 2 2 0 Ribosomal protein S26e Glyco_hydro_76 PF03663.14 EGG05863.1 - 9.2e-49 166.9 15.8 1.1e-48 166.6 15.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 EGG05863.1 - 0.01 14.3 3.2 0.12 10.8 0.9 2.8 2 1 1 3 3 3 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_47 PF01532.20 EGG05864.1 - 5.1e-111 371.8 0.1 2.3e-60 204.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Spb1_C PF07780.12 EGG05865.1 - 1.2e-70 237.5 18.3 1.2e-70 237.5 18.3 3.6 4 0 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 EGG05865.1 - 2.9e-55 187.1 0.1 1.2e-54 185.2 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EGG05865.1 - 1.4e-42 145.3 8.9 1.4e-42 145.3 8.9 6.0 3 2 0 3 3 3 1 Domain of unknown function (DUF3381) LPD3 PF18798.1 EGG05865.1 - 0.045 14.0 1.0 0.17 12.2 1.0 1.9 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 3 HORMA PF02301.18 EGG05869.1 - 1e-10 41.6 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 HORMA domain DUF202 PF02656.15 EGG05870.1 - 0.066 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) FixQ PF05545.11 EGG05870.1 - 0.15 12.1 0.2 0.27 11.2 0.2 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ PRCC PF10253.9 EGG05870.1 - 5 7.9 13.8 0.9 10.3 2.6 2.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting zf_Rg PF17915.1 EGG05871.1 - 0.13 11.6 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 Reverse gyrase zinc finger GTP_EFTU PF00009.27 EGG05874.1 - 3.6e-67 225.7 0.3 5e-67 225.2 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGG05874.1 - 4.4e-29 100.7 0.0 1.2e-28 99.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EGG05874.1 - 7.2e-21 74.0 0.0 1.9e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGG05874.1 - 9.8e-14 51.5 0.2 3.8e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGG05874.1 - 7.6e-13 48.4 0.0 2.1e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EGG05874.1 - 5.6e-05 23.2 0.2 0.00011 22.2 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGG05874.1 - 0.16 11.7 0.5 0.51 10.1 0.2 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Phosphodiest PF01663.22 EGG05875.1 - 2.3e-06 27.5 1.8 4.6e-06 26.5 1.8 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Peptidase_C42 PF05533.12 EGG05876.1 - 0.066 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 Peptidase_C42 PF05533.12 EGG05877.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 AAA_2 PF07724.14 EGG05880.1 - 1.6e-49 168.3 0.0 1.3e-46 158.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGG05880.1 - 8.8e-33 112.4 4.2 1.8e-32 111.4 0.8 2.8 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EGG05880.1 - 1.3e-23 82.8 0.5 8.9e-23 80.2 0.1 2.7 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EGG05880.1 - 2.1e-23 83.2 0.0 1.4e-11 44.9 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 EGG05880.1 - 2.1e-17 63.0 3.4 2.1e-12 46.9 0.3 4.2 4 0 0 4 4 3 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 EGG05880.1 - 1.3e-12 47.9 0.4 1.3e-06 28.4 0.0 3.6 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGG05880.1 - 9.1e-12 45.7 11.5 0.00023 21.6 0.0 5.9 5 2 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 EGG05880.1 - 4.5e-09 36.7 1.8 0.021 15.1 0.0 5.0 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EGG05880.1 - 4.1e-08 33.1 0.0 7.7e-05 22.5 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGG05880.1 - 2e-07 30.9 0.0 0.013 15.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EGG05880.1 - 1.4e-06 27.9 0.0 0.07 12.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 EGG05880.1 - 3e-06 27.8 0.2 0.13 12.8 0.0 3.6 4 0 0 4 4 2 2 AAA domain AAA_33 PF13671.6 EGG05880.1 - 8.7e-06 26.0 0.0 0.073 13.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EGG05880.1 - 2e-05 24.0 0.7 0.12 11.6 0.0 3.3 3 1 1 4 4 4 2 TIP49 P-loop domain Mg_chelatase PF01078.21 EGG05880.1 - 3.6e-05 23.3 0.0 0.065 12.6 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGG05880.1 - 5.5e-05 23.5 0.3 0.43 10.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 EGG05880.1 - 9.6e-05 22.7 0.0 0.3 11.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 EGG05880.1 - 9.9e-05 22.1 0.1 2.7 7.7 0.0 4.1 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 EGG05880.1 - 0.00017 21.1 0.0 0.14 11.5 0.1 3.4 2 1 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 EGG05880.1 - 0.00022 21.0 0.0 0.21 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGG05880.1 - 0.0011 19.0 0.0 2.8 8.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGG05880.1 - 0.0011 19.4 0.3 0.26 11.8 0.0 3.3 3 0 0 3 3 3 1 ABC transporter TsaE PF02367.17 EGG05880.1 - 0.0018 18.2 0.0 2.6 8.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EGG05880.1 - 0.0023 17.9 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 EGG05880.1 - 0.0023 18.1 0.0 1.5 9.1 0.0 3.2 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 EGG05880.1 - 0.0031 17.8 0.3 6.2 7.1 0.0 4.5 4 1 1 5 5 5 0 AAA domain PhoH PF02562.16 EGG05880.1 - 0.0059 16.1 0.0 1.7 8.1 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein CENP-F_leu_zip PF10473.9 EGG05880.1 - 0.0095 16.0 5.1 0.0095 16.0 5.1 2.2 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ResIII PF04851.15 EGG05880.1 - 0.01 15.9 0.0 6 6.8 0.0 3.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 EGG05880.1 - 0.012 15.6 0.0 7.3 6.5 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 EGG05880.1 - 0.014 14.7 0.0 7.4 5.8 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 EGG05880.1 - 0.019 14.0 0.0 0.047 12.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Torsin PF06309.11 EGG05880.1 - 0.022 14.9 0.0 0.33 11.1 0.0 2.4 2 0 0 2 2 2 0 Torsin HIP1_clath_bdg PF16515.5 EGG05880.1 - 0.023 15.3 4.8 0.09 13.4 4.8 2.1 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NTPase_1 PF03266.15 EGG05880.1 - 0.042 13.7 0.4 9.1 6.2 0.0 4.0 5 0 0 5 5 4 0 NTPase AAA_23 PF13476.6 EGG05880.1 - 0.048 14.2 11.5 1.9 8.9 0.0 4.3 4 1 0 4 4 4 0 AAA domain APS_kinase PF01583.20 EGG05880.1 - 0.049 13.5 0.0 0.84 9.5 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_25 PF13481.6 EGG05880.1 - 0.052 13.1 0.1 15 5.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_3 PF07726.11 EGG05880.1 - 0.063 13.1 0.0 29 4.5 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EGG05880.1 - 0.1 12.3 0.0 7 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain BLOC1_2 PF10046.9 EGG05880.1 - 0.11 12.9 1.1 0.54 10.6 1.1 2.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 EGG05880.1 - 0.16 12.1 7.1 0.33 11.0 6.1 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FliJ PF02050.16 EGG05880.1 - 0.17 12.1 8.3 0.73 10.1 5.3 3.0 2 0 0 2 2 2 0 Flagellar FliJ protein Parvo_NS1 PF01057.17 EGG05880.1 - 0.17 10.9 0.0 5.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_15 PF13175.6 EGG05880.1 - 0.18 11.5 0.3 9 5.9 0.0 2.8 3 1 0 3 3 2 0 AAA ATPase domain Atg14 PF10186.9 EGG05880.1 - 0.19 10.8 5.6 0.37 9.8 5.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlxA PF14282.6 EGG05880.1 - 0.22 11.5 3.4 0.77 9.8 0.4 2.8 2 1 1 3 3 2 0 FlxA-like protein Rx_N PF18052.1 EGG05880.1 - 0.24 11.7 4.5 0.37 11.1 3.1 2.1 2 0 0 2 2 1 0 Rx N-terminal domain Spc7 PF08317.11 EGG05880.1 - 0.42 9.5 10.1 1.2 7.9 9.4 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 EGG05880.1 - 0.68 10.4 4.0 3.2 8.2 0.7 2.9 1 1 1 2 2 2 0 Snapin/Pallidin BST2 PF16716.5 EGG05880.1 - 0.8 10.3 3.4 1.5 9.5 1.0 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Mod_r PF07200.13 EGG05880.1 - 1 9.5 5.0 0.7 10.0 1.9 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein LUC7 PF03194.15 EGG05880.1 - 2.7 7.6 8.6 1.7 8.2 3.9 2.3 2 0 0 2 2 2 0 LUC7 N_terminus ubiquitin PF00240.23 EGG05881.1 - 1.8e-237 767.7 36.5 2.9e-33 113.4 0.4 7.0 7 0 0 7 7 7 7 Ubiquitin family Rad60-SLD PF11976.8 EGG05881.1 - 3.3e-111 363.2 42.0 2.6e-15 56.0 0.6 7.0 7 0 0 7 7 7 7 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGG05881.1 - 1.5e-37 127.9 18.3 0.0015 19.0 0.1 9.1 7 7 0 7 7 7 7 Ubiquitin-like domain TBK1_ULD PF18396.1 EGG05881.1 - 8.2e-26 89.8 11.0 0.074 13.0 0.0 7.2 7 0 0 7 7 7 7 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGG05881.1 - 3.4e-22 78.6 19.4 0.14 12.6 0.1 7.1 7 0 0 7 7 7 7 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGG05881.1 - 5.2e-22 78.0 10.5 0.34 11.0 0.0 8.1 7 0 0 7 7 7 7 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGG05881.1 - 9.2e-22 77.6 5.9 0.56 10.8 0.0 7.2 1 1 3 7 7 7 7 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 EGG05881.1 - 1.8e-12 47.1 5.8 2.3 7.5 0.0 6.2 6 0 0 6 6 6 6 RNA methyltransferase Big_7 PF17957.1 EGG05881.1 - 2.3e-10 41.1 0.7 64 4.4 0.0 7.1 7 0 0 7 7 7 0 Bacterial Ig domain DUF3861 PF12977.7 EGG05881.1 - 5.1e-09 36.2 9.4 25 5.1 0.0 7.2 7 0 0 7 7 7 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 EGG05881.1 - 1.2e-08 35.2 0.0 1e+02 3.4 0.0 7.6 7 0 0 7 7 7 0 Protein of unknown function (DUF2870) TmoB PF06234.12 EGG05881.1 - 2.8e-08 33.7 11.7 29 4.9 0.0 8.4 7 7 0 7 7 7 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 EGG05881.1 - 4.1e-08 33.3 9.6 19 5.4 0.0 6.7 7 0 0 7 7 7 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_5 PF13710.6 EGG05881.1 - 7.9e-08 32.0 12.4 23 5.0 0.0 7.3 7 0 0 7 7 7 0 ACT domain DUF969 PF06149.12 EGG05881.1 - 2.3e-07 30.5 2.1 39 3.5 0.0 6.8 7 0 0 7 7 7 0 Protein of unknown function (DUF969) Ubiquitin_4 PF18036.1 EGG05881.1 - 4e-07 30.0 48.3 32 4.6 0.2 13.7 14 0 0 14 14 14 0 Ubiquitin-like domain DUF493 PF04359.14 EGG05881.1 - 9.9e-06 26.1 0.3 2.6e+02 2.3 0.0 6.7 7 0 0 7 7 7 0 Protein of unknown function (DUF493) ACT_4 PF13291.6 EGG05881.1 - 1.2e-05 25.8 6.2 1.5e+02 3.1 0.0 7.0 7 0 0 7 7 7 0 ACT domain NEAT PF05031.12 EGG05881.1 - 2.8e-05 24.7 7.3 3.2 8.4 1.9 4.6 1 1 3 4 4 4 1 Iron Transport-associated domain ORF11CD3 PF10549.9 EGG05881.1 - 0.00023 21.2 0.0 3e+02 1.6 0.0 6.6 7 0 0 7 7 7 0 ORF11CD3 domain Pullulanase_N2 PF17967.1 EGG05881.1 - 0.0069 17.2 0.1 6.2e+02 1.3 0.0 5.5 6 0 0 6 6 6 0 Pullulanase N2 domain ProRS-C_2 PF09181.10 EGG05881.1 - 0.016 15.4 15.2 1.3e+02 2.8 0.1 6.9 7 0 0 7 7 7 0 Prolyl-tRNA synthetase, C-terminal Phage_sheath_1N PF17481.2 EGG05881.1 - 0.23 11.9 20.6 1.2e+02 3.3 0.1 6.7 1 1 3 5 5 5 0 Phage tail sheath protein beta-sandwich domain FlgD_ig PF13860.6 EGG05881.1 - 0.33 10.9 22.1 87 3.1 0.1 7.2 7 0 0 7 7 7 0 FlgD Ig-like domain Tash_PEST PF07708.11 EGG05881.1 - 0.72 10.1 53.5 12 6.2 1.4 7.3 7 0 0 7 7 7 0 Tash protein PEST motif Ipi1_N PF12333.8 EGG05882.1 - 7.3e-15 55.4 0.1 1.1e-13 51.6 0.1 2.9 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.7 EGG05882.1 - 0.0098 15.9 0.0 0.93 9.5 0.0 3.2 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 MBOAT_2 PF13813.6 EGG05882.1 - 0.034 14.4 0.3 1.5 9.2 0.1 2.6 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family 4F5 PF04419.14 EGG05883.1 - 0.0023 18.8 9.1 0.004 18.0 9.1 1.4 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.7 EGG05883.1 - 0.011 15.8 1.5 0.011 15.8 1.5 1.8 2 1 0 2 2 2 0 Zinc-binding zf-C2H2_4 PF13894.6 EGG05883.1 - 0.11 13.4 0.1 0.2 12.6 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger ARID PF01388.21 EGG05884.1 - 1e-14 55.0 0.1 1e-14 55.0 0.1 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain MPM1 PF17234.2 EGG05884.1 - 6.7 6.9 17.2 0.42 10.9 1.5 2.8 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF4407 PF14362.6 EGG05885.1 - 0.0021 17.5 0.5 0.0021 17.5 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) PDCD7 PF16021.5 EGG05885.1 - 0.0041 16.3 0.9 0.0053 15.9 0.9 1.1 1 0 0 1 1 1 1 Programmed cell death protein 7 GPS2_interact PF15784.5 EGG05885.1 - 0.0057 17.1 5.6 0.011 16.2 5.6 1.5 1 0 0 1 1 1 1 G-protein pathway suppressor 2-interacting domain ABC_tran_CTD PF16326.5 EGG05885.1 - 0.044 14.0 4.6 0.073 13.3 4.6 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain SKA1 PF07160.12 EGG05885.1 - 0.044 13.6 4.7 0.06 13.2 4.7 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DASH_Spc19 PF08287.11 EGG05885.1 - 0.054 13.4 3.8 0.082 12.8 3.8 1.3 1 0 0 1 1 1 0 Spc19 ADIP PF11559.8 EGG05885.1 - 0.076 13.1 4.4 0.1 12.6 4.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 EGG05885.1 - 0.15 12.6 4.3 0.22 12.0 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Casc1 PF12366.8 EGG05885.1 - 0.7 9.4 6.2 0.97 8.9 6.2 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 XhlA PF10779.9 EGG05885.1 - 0.95 9.7 4.1 1.6 9.0 4.1 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Vfa1 PF08432.10 EGG05885.1 - 0.99 9.7 13.3 1.3 9.3 13.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FlxA PF14282.6 EGG05885.1 - 1.2 9.2 13.4 4.8 7.2 13.4 2.2 1 1 0 1 1 1 0 FlxA-like protein Peptidase_S49_N PF08496.10 EGG05885.1 - 1.5 8.8 6.9 2.3 8.3 6.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal eIF-3c_N PF05470.12 EGG05885.1 - 2 6.7 7.3 2.1 6.5 7.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4337 PF14235.6 EGG05885.1 - 2.3 8.3 5.5 3.6 7.7 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CASP_C PF08172.12 EGG05885.1 - 3.9 6.7 10.3 0.15 11.4 3.9 1.7 2 0 0 2 2 2 0 CASP C terminal Dicty_REP PF05086.12 EGG05885.1 - 9.5 4.0 9.0 10 3.9 9.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NTP_transferase PF00483.23 EGG05886.1 - 0.00047 19.8 0.0 0.00055 19.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase RicinB_lectin_2 PF14200.6 EGG05887.1 - 0.042 14.6 0.0 0.099 13.4 0.0 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like SNF2_N PF00176.23 EGG05888.1 - 2.1e-63 214.2 0.8 3.6e-63 213.4 0.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 EGG05888.1 - 1.5e-43 148.3 14.6 3.7e-43 147.1 14.6 1.7 1 0 0 1 1 1 1 DNA-binding domain Helicase_C PF00271.31 EGG05888.1 - 5.4e-18 65.4 0.1 2.3e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG05888.1 - 9.5e-07 29.0 0.0 2.8e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGG05888.1 - 2.3e-05 23.7 2.1 0.0042 16.3 0.0 3.4 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 baeRF_family12 PF18856.1 EGG05888.1 - 0.027 15.0 0.9 0.057 14.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 DnaJ PF00226.31 EGG05889.1 - 1.3e-08 34.8 0.0 1.4e-07 31.6 0.0 2.7 3 1 0 3 3 3 1 DnaJ domain TIC20 PF16166.5 EGG05889.1 - 0.0038 17.0 0.1 0.016 15.0 0.1 1.9 2 0 0 2 2 2 1 Chloroplast import apparatus Tic20-like TMEM132D_N PF15705.5 EGG05891.1 - 0.074 12.9 0.0 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term Mito_carr PF00153.27 EGG05894.1 - 4e-39 132.4 2.1 2.4e-19 69.1 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Periviscerokin PF08259.11 EGG05894.1 - 0.063 13.5 0.8 0.36 11.2 0.8 2.4 1 0 0 1 1 1 0 Periviscerokinin family SNF2_N PF00176.23 EGG05895.1 - 2.8e-75 253.2 0.7 3.9e-75 252.7 0.7 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG05895.1 - 1.2e-13 51.3 0.0 6.5e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EGG05895.1 - 0.00096 19.1 4.7 0.00096 19.1 4.7 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGG05895.1 - 0.0018 18.1 6.2 0.077 12.9 1.3 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG05895.1 - 0.072 13.0 2.5 0.26 11.2 2.5 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGG05895.1 - 0.25 11.2 4.4 4.4 7.3 5.2 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG05895.1 - 0.37 10.9 4.8 3.8 7.6 0.5 2.9 2 0 0 2 2 2 0 RING-type zinc-finger Med3 PF11593.8 EGG05895.1 - 1.6 7.8 15.5 0.022 13.9 7.8 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal TPT PF03151.16 EGG05896.1 - 4.8e-12 45.8 10.0 1.6e-07 31.0 2.1 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 EGG05896.1 - 1.3e-10 41.6 28.1 1.9e-05 24.8 7.1 3.0 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 EGG05896.1 - 5.9e-10 38.8 10.6 1.1e-09 38.0 10.6 1.4 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EGG05896.1 - 2.2e-08 33.6 3.4 2.7e-08 33.3 3.4 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 EGG05896.1 - 9.9e-05 21.7 3.0 9.9e-05 21.7 3.0 2.1 2 1 1 3 3 3 1 Purine nucleobase transmembrane transport TMEM234 PF10639.9 EGG05896.1 - 1.5 8.9 10.3 0.052 13.6 1.8 2.4 3 0 0 3 3 3 0 Putative transmembrane family 234 GATA PF00320.27 EGG05897.1 - 5.8e-10 38.6 0.3 5.8e-10 38.6 0.3 2.5 3 0 0 3 3 3 1 GATA zinc finger bZIP_1 PF00170.21 EGG05898.1 - 0.0031 17.6 0.4 0.0031 17.6 0.4 1.5 2 0 0 2 2 2 1 bZIP transcription factor Dscam_C PF12355.8 EGG05899.1 - 1.6 9.7 8.6 0.084 13.8 2.6 2.1 2 1 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal zf-CCHC PF00098.23 EGG05900.1 - 2.9e-05 23.9 16.6 0.0021 18.1 2.9 3.1 2 1 0 2 2 2 2 Zinc knuckle Rad50_zn_hook PF04423.14 EGG05900.1 - 0.0095 15.8 0.8 0.038 13.8 0.8 2.0 1 0 0 1 1 1 1 Rad50 zinc hook motif zf-CCHC_4 PF14392.6 EGG05900.1 - 0.014 15.1 7.5 0.13 12.0 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 EGG05900.1 - 0.033 14.0 12.9 0.086 12.7 1.8 2.9 3 0 0 3 3 3 0 Zinc knuckle Mut7-C PF01927.16 EGG05900.1 - 0.36 10.9 3.6 17 5.5 2.8 2.2 2 0 0 2 2 2 0 Mut7-C RNAse domain Zn_ribbon_SprT PF17283.2 EGG05900.1 - 1.6 8.7 8.0 1.1 9.2 0.3 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-nanos PF05741.13 EGG05900.1 - 3.4 8.0 10.0 11 6.4 1.5 3.0 3 0 0 3 3 3 0 Nanos RNA binding domain DnaJ_CXXCXGXG PF00684.19 EGG05900.1 - 7.1 7.1 16.8 5.7 7.4 13.0 2.6 2 1 0 2 2 2 0 DnaJ central domain Plasmodium_HRP PF05403.11 EGG05901.1 - 3e-06 27.2 35.7 5.3e-05 23.1 20.2 2.0 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) DUF4573 PF15140.6 EGG05901.1 - 0.0023 17.7 9.0 0.018 14.8 3.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) Drc1-Sld2 PF11719.8 EGG05902.1 - 4e-17 62.9 15.7 4e-17 62.9 15.7 3.3 1 1 2 3 3 3 1 DNA replication and checkpoint protein Imm-NTF2 PF15655.6 EGG05902.1 - 0.0094 16.2 2.3 0.024 14.9 2.3 1.6 1 0 0 1 1 1 1 NTF2 fold immunity protein RCC1 PF00415.18 EGG05903.1 - 1.6e-20 73.4 2.7 2.7e-05 24.7 0.0 7.2 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG05903.1 - 3.1e-05 23.6 9.3 0.061 13.1 0.1 5.3 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.32 EGG05904.1 - 3.2e-20 72.1 19.3 1.3e-05 25.9 0.3 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 EGG05904.1 - 2.5e-19 69.6 0.1 4.4e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 EGG05904.1 - 0.0013 19.0 0.0 0.079 13.3 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WHIM1 PF15612.6 EGG05905.1 - 9.1e-07 28.3 0.1 1.7e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 HSP20 PF00011.21 EGG05906.1 - 6.5e-14 51.9 0.2 6.9e-14 51.8 0.2 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG05906.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 0 HSP20-like domain found in ArsA PLDc PF00614.22 EGG05908.1 - 2.9e-15 55.7 0.4 2.1e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.24 EGG05908.1 - 2.6e-12 46.7 2.9 5.1e-11 42.5 0.1 3.0 3 0 0 3 3 3 1 PX domain PLDc_2 PF13091.6 EGG05908.1 - 3.4e-12 46.4 0.0 3.5e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PH PF00169.29 EGG05908.1 - 0.027 15.0 2.3 0.65 10.5 2.3 2.5 1 1 0 1 1 1 0 PH domain GDP_Man_Dehyd PF16363.5 EGG05909.1 - 1.2e-155 518.0 0.0 1.3e-155 517.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG05909.1 - 3.4e-72 242.8 0.0 4.2e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGG05909.1 - 9.1e-07 28.3 0.0 1.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGG05909.1 - 0.00026 20.2 0.0 0.00041 19.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EGG05909.1 - 0.00056 19.5 0.0 0.0009 18.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family SPESP1 PF15754.5 EGG05910.1 - 1 8.4 2.8 1.4 8.1 2.8 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Trypan_PARP PF05887.11 EGG05910.1 - 3.6 7.6 18.7 1.1 9.3 15.5 1.6 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Sec39 PF08314.11 EGG05911.1 - 1.3e-72 245.5 0.8 2.1e-72 244.7 0.8 1.3 1 0 0 1 1 1 1 Secretory pathway protein Sec39 LRR_4 PF12799.7 EGG05912.1 - 0.00031 21.1 34.9 0.15 12.6 0.3 8.0 8 2 1 9 9 9 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGG05912.1 - 0.001 18.9 19.4 0.27 11.4 0.1 8.6 10 0 0 10 10 10 1 Leucine Rich repeat LRR_8 PF13855.6 EGG05912.1 - 0.6 9.9 23.4 2.3 8.1 0.7 6.2 6 0 0 6 6 6 0 Leucine rich repeat SUR7 PF06687.12 EGG05913.1 - 2e-20 73.3 15.4 2.6e-20 73.0 15.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4381 PF14316.6 EGG05913.1 - 0.47 10.7 3.7 14 5.9 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) MpPF26 PF07666.11 EGG05913.1 - 5.3 7.2 6.8 1.5 9.0 1.0 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 Trp_oprn_chp PF09534.10 EGG05913.1 - 7.3 6.4 11.7 0.15 11.8 1.9 2.7 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Acetyltransf_13 PF13880.6 EGG05914.1 - 8.3e-23 80.2 0.0 1.3e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 EGG05914.1 - 0.00083 19.7 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG05914.1 - 0.0021 18.3 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 EGG05914.1 - 0.012 15.0 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase zf-CCCH PF00642.24 EGG05915.1 - 4.1e-15 55.3 25.9 1.1e-05 25.2 1.0 4.2 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGG05915.1 - 5.3e-13 48.6 36.0 1.3e-06 28.2 3.2 4.1 4 0 0 4 4 4 4 Zinc finger domain Torus PF16131.5 EGG05915.1 - 2e-10 41.3 22.5 0.0002 22.0 0.7 4.0 1 1 3 4 4 4 4 Torus domain zf-CCCH_4 PF18044.1 EGG05915.1 - 6.4e-07 29.0 0.6 6.4e-07 29.0 0.6 3.6 4 0 0 4 4 4 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EGG05915.1 - 0.0061 16.8 19.0 0.41 10.9 0.9 2.8 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGG05915.1 - 0.095 13.2 27.4 0.11 13.0 3.1 4.5 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger zf-HIT PF04438.16 EGG05916.1 - 0.031 14.2 1.3 0.06 13.2 1.3 1.4 1 0 0 1 1 1 0 HIT zinc finger Glycohydro_20b2 PF14845.6 EGG05918.1 - 0.083 13.5 0.6 0.25 12.0 0.2 1.9 2 0 0 2 2 2 0 beta-acetyl hexosaminidase like Aldose_epim PF01263.20 EGG05921.1 - 3.7e-17 62.6 0.0 1.7e-08 34.2 0.0 2.8 2 1 0 2 2 2 2 Aldose 1-epimerase Lactonase PF10282.9 EGG05922.1 - 1.1e-77 261.6 0.1 1.3e-77 261.4 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 EGG05922.1 - 0.00024 20.9 4.5 0.46 10.5 0.0 4.7 4 1 1 5 5 5 2 WD40-like Beta Propeller Repeat dCache_1 PF02743.18 EGG05922.1 - 0.024 14.5 0.5 0.11 12.3 0.3 2.1 2 0 0 2 2 2 0 Cache domain NolB PF17398.2 EGG05923.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein NolB UCR_hinge PF02320.16 EGG05924.1 - 1.8e-24 85.7 6.4 1.8e-24 85.7 6.4 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein DUF4611 PF15387.6 EGG05924.1 - 0.0076 16.4 0.5 0.012 15.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Sigma70_ner PF04546.13 EGG05924.1 - 0.011 15.6 0.7 0.014 15.3 0.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Ribosomal_60s PF00428.19 EGG05924.1 - 0.042 14.4 5.3 0.066 13.8 5.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein GET2 PF08690.10 EGG05924.1 - 0.069 12.8 0.9 0.081 12.6 0.9 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 Atrophin-1 PF03154.15 EGG05924.1 - 1.5 7.0 6.7 1.6 6.9 6.7 1.0 1 0 0 1 1 1 0 Atrophin-1 family Herpes_DNAp_acc PF04929.12 EGG05924.1 - 1.7 7.6 5.6 2.1 7.2 5.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor F-box PF00646.33 EGG05926.1 - 0.08 12.8 0.7 0.18 11.7 0.7 1.6 1 0 0 1 1 1 0 F-box domain bZIP_1 PF00170.21 EGG05927.1 - 1.1e-05 25.4 3.1 2.7e-05 24.2 3.1 1.8 1 1 0 1 1 1 1 bZIP transcription factor Cas_Cas4 PF01930.17 EGG05927.1 - 0.015 15.4 5.4 0.022 14.9 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF83 DUF641 PF04859.12 EGG05927.1 - 0.32 11.3 5.4 0.33 11.3 3.7 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Draxin PF15550.6 EGG05927.1 - 0.9 9.3 14.9 0.64 9.8 13.7 1.3 1 1 0 1 1 1 0 Draxin DUF2703 PF10865.8 EGG05927.1 - 2.2 8.5 6.2 2.3 8.4 4.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) zf-RING_11 PF17123.5 EGG05928.1 - 8e-06 25.5 1.4 1.9e-05 24.3 1.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGG05928.1 - 0.0048 17.2 2.2 0.012 15.9 2.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG05928.1 - 0.052 13.6 1.1 0.13 12.3 1.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger SF3A3 PF16837.5 EGG05928.1 - 3.4 8.2 6.1 40 4.8 2.4 3.6 2 1 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Lung_7-TM_R PF06814.13 EGG05929.1 - 6.6e-63 212.7 15.9 6.6e-63 212.7 15.9 1.8 2 0 0 2 2 2 1 Lung seven transmembrane receptor DUF3099 PF11298.8 EGG05929.1 - 0.036 14.2 0.6 0.036 14.2 0.6 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF3099) DUF3671 PF12420.8 EGG05929.1 - 7.5 6.7 6.2 0.99 9.5 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF2721 PF11026.8 EGG05930.1 - 0.0019 18.1 0.4 0.0019 18.1 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) Q_salvage PF10343.9 EGG05931.1 - 7e-18 65.2 0.0 1.8e-17 63.9 0.0 1.5 2 0 0 2 2 2 1 Potential Queuosine, Q, salvage protein family DUF1590 PF07629.11 EGG05931.1 - 8.1 6.3 9.2 1.1 9.1 2.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1590) AMP-binding PF00501.28 EGG05932.1 - 4.5e-21 74.9 0.0 2.4e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme HMD PF03201.16 EGG05932.1 - 0.021 15.0 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase GBP_PSP PF02425.15 EGG05932.1 - 0.035 13.8 0.3 0.097 12.3 0.3 1.7 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide PP-binding PF00550.25 EGG05932.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site DUF3536 PF12055.8 EGG05932.1 - 0.22 10.8 0.1 0.35 10.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) AMP-binding PF00501.28 EGG05935.1 - 9.3e-22 77.2 0.0 8.3e-21 74.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme HMD PF03201.16 EGG05935.1 - 0.06 13.6 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase PP-binding PF00550.25 EGG05935.1 - 0.075 13.4 0.0 0.21 12.0 0.0 1.9 1 1 0 1 1 1 0 Phosphopantetheine attachment site GBP_PSP PF02425.15 EGG05935.1 - 0.15 11.7 0.1 0.41 10.3 0.1 1.7 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide DUF202 PF02656.15 EGG05936.1 - 1e-09 38.7 5.5 2.7e-09 37.3 5.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF202) DUF1244 PF06844.11 EGG05938.1 - 0.17 12.0 1.3 0.27 11.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) Ribosomal_L22 PF00237.19 EGG05939.1 - 1.9e-20 73.0 0.3 3.1e-20 72.3 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Pox_I1 PF03289.13 EGG05941.1 - 0.031 13.4 0.2 0.055 12.6 0.2 1.3 1 0 0 1 1 1 0 Poxvirus protein I1 Nas2_N PF18265.1 EGG05941.1 - 2.7 8.0 8.3 2.7 8.0 0.4 2.8 3 0 0 3 3 3 0 Nas2 N_terminal domain Pet191_N PF10203.9 EGG05942.1 - 8.7e-27 93.2 1.7 9.5e-27 93.1 1.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COX16 PF14138.6 EGG05943.1 - 2.4e-14 53.6 2.2 1.7e-12 47.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase assembly protein COX16 SPATA9 PF15824.5 EGG05944.1 - 0.019 14.3 0.1 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 Sec20 PF03908.13 EGG05944.1 - 2.6 8.0 5.1 11 6.1 0.4 2.7 2 1 1 3 3 3 0 Sec20 SurE PF01975.17 EGG05945.1 - 5.4e-41 140.5 0.0 8.1e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE DUF1940 PF09155.10 EGG05945.1 - 0.21 11.7 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) Methyltransf_4 PF02390.17 EGG05946.1 - 4.6e-48 163.0 0.1 1.6e-36 125.4 0.1 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_25 PF13649.6 EGG05946.1 - 0.0043 17.7 0.0 0.013 16.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EGG05946.1 - 0.0094 15.5 0.0 0.034 13.7 0.0 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 MTS PF05175.14 EGG05946.1 - 0.02 14.4 0.0 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EGG05946.1 - 0.13 13.1 0.0 0.41 11.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain CEBP_ZZ PF16366.5 EGG05947.1 - 0.0048 17.1 5.0 0.0093 16.2 0.9 2.8 3 0 0 3 3 3 1 Cytoplasmic polyadenylation element-binding protein ZZ domain Catalase PF00199.19 EGG05948.1 - 1.3e-85 287.9 0.0 1.4e-85 287.7 0.0 1.0 1 0 0 1 1 1 1 Catalase NAM-associated PF14303.6 EGG05949.1 - 6.8e-05 23.7 6.7 0.0002 22.1 6.7 1.7 1 1 0 1 1 1 1 No apical meristem-associated C-terminal domain Catalase PF00199.19 EGG05950.1 - 2.1e-82 277.3 0.0 4e-81 273.1 0.0 2.0 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGG05950.1 - 1.9e-12 47.2 0.0 4.5e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive RRM_1 PF00076.22 EGG05951.1 - 3.4e-19 68.4 0.0 3.8e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG05951.1 - 0.00035 20.1 0.0 0.0004 20.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 EGG05952.1 - 1.2e-61 207.0 0.5 1.4e-61 206.8 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG05952.1 - 3.1e-36 124.2 0.1 4.6e-36 123.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG05952.1 - 1.7e-13 50.4 0.0 2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG05952.1 - 1.5e-06 28.2 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG05952.1 - 2.4e-05 24.3 1.1 0.18 11.7 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGG05952.1 - 3.7e-05 23.2 0.1 5.5e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGG05952.1 - 5.9e-05 22.7 0.1 0.00011 21.8 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGG05952.1 - 0.0053 17.2 0.5 0.01 16.2 0.5 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG05952.1 - 0.019 15.2 0.1 0.57 10.4 0.0 2.6 1 1 1 2 2 2 0 AAA domain Septin PF00735.18 EGG05952.1 - 0.02 14.2 0.1 0.055 12.8 0.0 1.6 2 0 0 2 2 2 0 Septin G-alpha PF00503.20 EGG05952.1 - 0.071 12.3 0.3 2.1 7.4 0.0 2.3 1 1 1 3 3 3 0 G-protein alpha subunit ATPase PF06745.13 EGG05952.1 - 0.12 11.7 0.3 13 5.1 0.0 2.1 2 0 0 2 2 2 0 KaiC TniB PF05621.11 EGG05952.1 - 0.13 11.7 0.0 0.38 10.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein RRM_1 PF00076.22 EGG05953.1 - 4.1e-16 58.6 0.0 5.5e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG05953.1 - 0.0014 18.3 0.0 0.0017 17.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Esterase PF00756.20 EGG05957.1 - 3.4e-45 154.7 0.0 3.9e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 EGG05957.1 - 0.0034 16.3 0.0 0.0065 15.4 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EGG05957.1 - 0.0039 16.7 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGG05957.1 - 0.016 14.4 0.0 0.048 12.9 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG05957.1 - 0.024 14.3 0.0 0.044 13.4 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold PAS_9 PF13426.7 EGG05959.1 - 4.1e-12 46.3 0.0 6.3e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 EGG05959.1 - 0.00034 20.8 0.0 0.0098 16.1 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 EGG05959.1 - 0.0018 18.2 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EGG05959.1 - 0.0087 16.0 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold Polysacc_deac_1 PF01522.21 EGG05960.1 - 1.6e-06 28.0 0.2 5.9e-06 26.2 0.2 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase Phage_int_SAM_1 PF02899.17 EGG05961.1 - 0.0012 19.1 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 EGG05961.1 - 0.0041 17.6 0.0 0.008 16.6 0.0 1.4 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 EGG05961.1 - 0.04 14.2 0.0 0.13 12.6 0.0 1.7 1 1 0 1 1 1 0 Phage integrase SAM-like domain Rhodanese PF00581.20 EGG05962.1 - 1.2e-07 32.2 0.0 0.003 18.0 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain T2SSM PF04612.12 EGG05962.1 - 0.048 13.7 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M ATP-synt_F PF01990.17 EGG05963.1 - 6.1e-30 103.4 0.2 7.1e-30 103.2 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Acyl-CoA_dh_1 PF00441.24 EGG05964.1 - 4.3e-42 143.9 0.0 5.8e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGG05964.1 - 3.4e-32 111.4 0.0 6.2e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGG05964.1 - 9e-23 80.3 0.0 1.8e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGG05964.1 - 6.4e-14 52.4 0.0 8.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyltransferase PF01553.21 EGG05965.1 - 1e-14 54.3 0.0 1.8e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DDDD PF10161.9 EGG05966.1 - 6 6.7 6.2 11 5.9 6.2 1.4 1 0 0 1 1 1 0 Putative mitochondrial precursor protein RRM_1 PF00076.22 EGG05967.1 - 3.5e-05 23.5 0.0 0.00041 20.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1064 PF06356.11 EGG05969.1 - 0.00049 20.4 0.5 0.001 19.4 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1064) RyR PF02026.16 EGG05969.1 - 0.071 13.3 0.9 2.1 8.6 0.1 3.0 3 0 0 3 3 3 0 RyR domain adh_short PF00106.25 EGG05970.1 - 3.9e-41 140.7 0.1 4.8e-41 140.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG05970.1 - 5.2e-40 137.5 0.0 6e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG05970.1 - 2.8e-08 33.9 0.8 6e-08 32.8 0.8 1.5 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGG05970.1 - 1.5e-07 31.1 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG05970.1 - 2e-06 27.5 0.0 3.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 EGG05970.1 - 0.00091 19.2 0.1 0.0018 18.2 0.1 1.4 2 0 0 2 2 2 1 YjeF-related protein N-terminus NAD_binding_10 PF13460.6 EGG05970.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGG05970.1 - 0.018 14.2 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1462 PF07315.11 EGG05970.1 - 0.018 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) NmrA PF05368.13 EGG05970.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RhoGEF PF00621.20 EGG05970.1 - 0.067 13.4 0.1 0.094 12.9 0.1 1.2 1 0 0 1 1 1 0 RhoGEF domain 3HCDH_N PF02737.18 EGG05970.1 - 0.07 13.0 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LDcluster4 PF18306.1 EGG05970.1 - 0.29 10.7 2.5 7.9 6.0 0.1 2.8 3 0 0 3 3 3 0 SLOG cluster4 family DUF4441 PF14536.6 EGG05970.1 - 0.32 11.2 4.0 0.63 10.3 4.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4441) UPF0242 PF06785.11 EGG05972.1 - 0.0032 17.6 0.9 0.52 10.4 0.1 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus RVT_3 PF13456.6 EGG05974.1 - 8.4e-08 32.1 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like DEAD PF00270.29 EGG05975.1 - 0.00031 20.5 0.0 0.00063 19.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG05975.1 - 0.00043 20.6 0.0 0.00084 19.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4577 PF15145.6 EGG05976.1 - 6 6.9 5.1 2.2 8.3 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) ApbA_C PF08546.11 EGG05977.1 - 6.7e-05 23.1 2.3 0.91 9.7 0.1 3.8 1 1 3 4 4 4 2 Ketopantoate reductase PanE/ApbA C terminal Crystall_4 PF17945.1 EGG05977.1 - 0.0011 19.4 2.1 18 5.9 0.0 4.1 4 0 0 4 4 4 0 Beta/Gamma crystallin Diphthami_syn_2 PF01902.17 EGG05977.1 - 0.0017 17.9 3.4 0.32 10.5 0.1 2.9 1 1 2 3 3 3 2 Diphthamide synthase CNTF PF01110.17 EGG05977.1 - 0.006 16.0 1.2 2.8 7.3 0.1 2.2 1 1 2 3 3 3 3 Ciliary neurotrophic factor CPSase_L_D2 PF02786.17 EGG05977.1 - 0.037 13.5 2.4 2.1 7.8 0.3 2.2 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain AbfS_sensor PF18225.1 EGG05977.1 - 0.046 13.6 0.0 15 5.6 0.0 3.1 2 1 1 3 3 3 0 Sensor histidine kinase (AbfS) sensor domain DUF5045 PF16464.5 EGG05977.1 - 0.057 13.7 1.6 45 4.4 0.0 4.0 3 2 1 5 5 5 0 Domain of unknown function (DUF5045) Filament PF00038.21 EGG05977.1 - 0.13 11.8 10.9 3 7.4 0.6 2.8 1 1 2 3 3 3 0 Intermediate filament protein CCDC-167 PF15188.6 EGG05977.1 - 0.17 12.2 7.7 9.2 6.7 0.5 3.6 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 PAPA-1 PF04795.12 EGG05977.1 - 0.27 12.1 12.7 0.85 10.5 2.6 2.8 1 1 2 3 3 3 0 PAPA-1-like conserved region DUF4548 PF15081.6 EGG05977.1 - 0.51 10.1 16.0 6.1 6.7 2.7 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4548) FlgN PF05130.12 EGG05977.1 - 0.55 10.7 19.4 2.6 8.5 2.6 3.8 1 1 2 3 3 3 0 FlgN protein TRL PF13146.6 EGG05977.1 - 0.62 10.4 4.8 15 6.0 0.0 4.1 5 0 0 5 5 5 0 TRL-like protein family RyR PF02026.16 EGG05977.1 - 0.71 10.1 8.2 14 5.9 0.3 3.6 1 1 2 3 3 3 0 RyR domain Cactin_mid PF10312.9 EGG05977.1 - 1.4 8.6 11.0 4.3 7.0 1.1 2.5 1 1 2 3 3 3 0 Conserved mid region of cactin DUF2682 PF10909.8 EGG05977.1 - 3.2 8.3 14.6 6.4 7.3 1.3 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF2682) PDZ_1 PF12812.7 EGG05977.1 - 8.2 6.5 7.8 42 4.2 0.2 3.8 3 2 0 3 3 3 0 PDZ-like domain UPF0020 PF01170.18 EGG05978.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF3341 PF11821.8 EGG05978.1 - 0.058 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) ETF_QO PF05187.13 EGG05979.1 - 5.1e-42 142.2 0.4 1e-41 141.3 0.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 EGG05979.1 - 5.1e-08 32.9 0.0 6.2e-05 22.7 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGG05979.1 - 6.8e-07 28.8 0.0 5.3e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EGG05979.1 - 1.1e-06 28.8 0.0 3.6e-06 27.1 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGG05979.1 - 3.4e-06 26.4 0.0 0.00036 19.7 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EGG05979.1 - 6e-05 22.4 0.0 9.3e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGG05979.1 - 0.00012 21.0 0.2 0.00018 20.3 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 EGG05979.1 - 0.00051 19.4 0.0 0.0012 18.2 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EGG05979.1 - 0.00059 19.2 0.2 0.00094 18.5 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG05979.1 - 0.00061 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EGG05979.1 - 0.0046 16.1 0.0 0.0064 15.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 EGG05979.1 - 0.022 15.3 0.0 2.6 8.7 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGG05979.1 - 0.027 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fer4_7 PF12838.7 EGG05979.1 - 0.053 14.1 0.3 0.12 13.0 0.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGG05979.1 - 0.12 12.5 0.6 0.35 11.0 0.6 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 EGG05979.1 - 0.14 11.2 0.2 0.23 10.5 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EGG05979.1 - 0.2 10.4 0.1 0.33 9.7 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Fer4_2 PF12797.7 EGG05979.1 - 2.4 8.4 4.7 0.38 11.0 0.6 1.9 2 0 0 2 2 1 0 4Fe-4S binding domain Exo84_C PF16528.5 EGG05981.1 - 6e-45 153.6 3.9 2.6e-44 151.5 3.9 1.9 1 1 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EGG05981.1 - 4.9e-08 33.0 0.2 8.4e-07 29.0 0.2 3.0 2 1 0 2 2 2 1 Vps51/Vps67 Arf PF00025.21 EGG05982.1 - 5.1e-66 221.4 0.0 5.7e-66 221.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGG05982.1 - 7.8e-11 41.7 0.0 2.5e-07 30.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGG05982.1 - 1.5e-08 34.3 0.0 2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGG05982.1 - 9.7e-08 32.3 0.0 2.3e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGG05982.1 - 1.6e-07 31.4 0.0 3.1e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EGG05982.1 - 3.5e-06 26.7 0.0 4.4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGG05982.1 - 4.5e-05 22.9 0.0 4.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EGG05982.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EGG05982.1 - 0.2 11.2 0.0 6.5 6.3 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B tRNA-synt_2b PF00587.25 EGG05983.1 - 1.8e-38 132.3 0.0 5.5e-38 130.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGG05983.1 - 1.7e-19 70.0 2.4 3.1e-19 69.2 2.4 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 EGG05983.1 - 0.093 12.8 3.1 0.18 11.9 3.1 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 EGG05983.1 - 0.87 9.9 4.9 0.92 9.8 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Prefoldin_2 PF01920.20 EGG05983.1 - 2.1 8.3 8.0 10 6.1 6.2 2.6 2 1 0 2 2 2 0 Prefoldin subunit ANAPC4_WD40 PF12894.7 EGG05984.1 - 2.2e-18 66.3 0.0 0.0051 17.1 0.0 5.9 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG05984.1 - 8.4e-18 64.4 9.1 0.021 15.7 0.3 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 EGG05984.1 - 0.00011 22.1 0.0 0.3 10.9 0.0 3.3 1 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGG05984.1 - 0.0041 16.5 0.3 3.8 6.7 0.1 2.9 3 1 1 4 4 4 2 WD40-like domain IKI3 PF04762.12 EGG05984.1 - 0.0044 15.1 0.0 0.52 8.2 0.0 2.3 1 1 1 2 2 2 2 IKI3 family MIP PF00230.20 EGG05985.1 - 2.8e-22 79.6 8.1 3.8e-22 79.1 8.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF512 PF04459.12 EGG05986.1 - 0.091 12.0 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF512) PSI_integrin PF17205.3 EGG05988.1 - 0.52 10.1 6.1 8.1 6.3 1.1 2.4 2 0 0 2 2 2 0 Integrin plexin domain ImcF-related_N PF14331.6 EGG05989.1 - 0.029 13.7 1.0 0.042 13.2 1.0 1.3 1 0 0 1 1 1 0 ImcF-related N-terminal domain ACCA PF03255.14 EGG05989.1 - 0.041 13.8 1.1 0.058 13.3 1.1 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ABC_tran_CTD PF16326.5 EGG05989.1 - 0.13 12.5 0.0 0.13 12.5 0.0 3.1 3 1 0 3 3 3 0 ABC transporter C-terminal domain SARS_3b PF12383.8 EGG05991.1 - 0.21 11.7 0.6 1.7 8.8 0.1 2.5 2 1 1 3 3 3 0 Severe acute respiratory syndrome coronavirus 3b protein Alpha_kinase PF02816.18 EGG05996.1 - 2.7e-07 30.9 0.0 5.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Alpha-kinase family DUF4412 PF14371.6 EGG05997.1 - 0.15 11.8 0.1 0.18 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) Cation_ATPase PF13246.6 EGG06000.1 - 3.9e-11 42.9 0.1 1.1e-10 41.5 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) PhoLip_ATPase_N PF16209.5 EGG06000.1 - 0.14 11.9 2.0 0.29 10.9 2.0 1.6 1 0 0 1 1 1 0 Phospholipid-translocating ATPase N-terminal SUIM_assoc PF16619.5 EGG06000.1 - 2.3 8.4 6.0 1.3 9.1 2.2 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Elf1 PF05129.13 EGG06001.1 - 1.2e-24 86.1 1.2 1.8e-24 85.6 1.2 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Glyco_hydro_31 PF01055.26 EGG06001.1 - 0.051 12.8 0.1 0.054 12.7 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 zf-RVT PF13966.6 EGG06001.1 - 0.057 14.1 0.6 0.096 13.4 0.6 1.3 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase zf-RING_UBOX PF13445.6 EGG06002.1 - 1.3e-07 31.5 1.9 1.3e-07 31.5 1.9 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG06002.1 - 1.2e-05 25.2 8.6 2.3e-05 24.2 3.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGG06002.1 - 7e-05 22.6 2.2 7e-05 22.6 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGG06002.1 - 9.9e-05 22.4 6.2 0.00013 22.0 2.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EGG06002.1 - 0.00025 20.8 2.5 0.00025 20.8 2.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG06002.1 - 0.00056 20.2 7.6 0.00071 19.9 2.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGG06002.1 - 0.0011 18.8 5.4 0.0069 16.2 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EGG06002.1 - 0.01 16.0 0.2 0.035 14.2 0.2 1.9 1 1 0 1 1 1 0 FYVE zinc finger MscS_porin PF12795.7 EGG06002.1 - 0.024 14.2 8.3 0.033 13.7 8.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain GLE1 PF07817.13 EGG06002.1 - 0.066 12.4 0.2 0.089 12.0 0.2 1.2 1 0 0 1 1 1 0 GLE1-like protein zf-Nse PF11789.8 EGG06002.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 EGG06002.1 - 0.33 10.8 5.0 1.2 9.1 1.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C2H2 PF00096.26 EGG06002.1 - 2.1 9.0 5.6 1.8 9.2 0.4 3.1 2 1 1 3 3 3 0 Zinc finger, C2H2 type DEAD PF00270.29 EGG06003.1 - 1e-37 129.6 0.1 2.1e-37 128.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG06003.1 - 5.5e-26 91.1 0.1 1.5e-24 86.4 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG06003.1 - 4.7e-08 33.2 0.0 7.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGG06003.1 - 0.024 14.0 0.0 0.077 12.3 0.0 1.8 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EGG06005.1 - 4.4e-49 166.6 0.1 1.1e-48 165.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG06005.1 - 8.6e-23 80.8 0.0 4.3e-22 78.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGG06005.1 - 8.2e-18 64.4 0.1 1.6e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGG06005.1 - 3e-07 30.6 3.8 3.1e-07 30.5 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF4349 PF14257.6 EGG06007.1 - 0.03 13.8 0.1 0.064 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Ferric_reduct PF01794.19 EGG06008.1 - 6.1e-07 29.6 6.1 7.6e-07 29.3 6.1 1.2 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Alpha_kinase PF02816.18 EGG06010.1 - 2e-14 54.1 1.4 2.8e-11 43.9 0.1 2.6 1 1 1 2 2 2 2 Alpha-kinase family UPF0061 PF02696.14 EGG06011.1 - 3.3e-101 339.4 0.4 2.9e-100 336.3 0.4 1.9 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family p450 PF00067.22 EGG06012.1 - 6.5e-83 279.0 0.0 8.1e-83 278.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.22 EGG06013.1 - 2.3e-66 224.9 1.3 9e-66 223.0 1.3 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase ABC_membrane PF00664.23 EGG06014.1 - 1.1e-36 127.0 9.8 1.8e-36 126.2 9.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGG06014.1 - 2.4e-33 115.5 0.0 4.5e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGG06014.1 - 4e-05 23.1 2.6 0.0046 16.4 0.0 2.4 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 EGG06014.1 - 0.0014 19.1 0.0 0.0073 16.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGG06014.1 - 0.0024 18.1 0.1 0.015 15.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG06014.1 - 0.0037 17.7 0.0 0.0099 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EGG06014.1 - 0.013 15.0 0.0 0.34 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_21 PF13304.6 EGG06014.1 - 0.021 14.6 0.1 1.5 8.6 0.0 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 EGG06014.1 - 0.025 14.6 0.1 0.51 10.4 0.1 2.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGG06014.1 - 0.055 13.0 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGG06014.1 - 0.058 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 EGG06014.1 - 0.065 13.1 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 EGG06014.1 - 0.14 12.4 1.1 2.3 8.5 0.4 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EGG06014.1 - 0.15 11.8 0.0 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGG06014.1 - 0.19 12.2 1.9 0.29 11.6 0.1 2.1 2 1 0 2 2 2 0 AAA domain MIT PF04212.18 EGG06015.1 - 0.00071 19.6 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TB2_DP1_HVA22 PF03134.19 EGG06015.1 - 0.086 12.8 2.6 0.11 12.4 1.3 1.9 2 0 0 2 2 2 0 TB2/DP1, HVA22 family CAC1F_C PF16885.5 EGG06015.1 - 0.97 9.0 5.0 3.1 7.4 5.0 1.8 1 1 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Pkinase PF00069.25 EGG06016.1 - 9.5e-64 215.3 0.0 1.1e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG06016.1 - 7.7e-46 156.5 0.0 9.3e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG06016.1 - 1.2e-06 28.1 0.0 3.3e-06 26.6 0.0 1.5 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGG06016.1 - 0.0046 15.8 0.0 0.0067 15.2 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGG06016.1 - 0.01 15.0 0.2 0.1 11.6 0.0 2.0 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.23 EGG06016.1 - 0.015 15.2 0.0 0.91 9.4 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG06016.1 - 0.086 12.2 0.0 0.18 11.1 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec10 PF07393.11 EGG06017.1 - 1.9e-93 314.2 0.0 5.3e-55 187.1 0.0 2.1 1 1 1 2 2 2 2 Exocyst complex component Sec10 F-box-like PF12937.7 EGG06017.1 - 4.7e-08 32.8 0.3 1.3e-07 31.4 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG06017.1 - 7.6e-07 28.9 2.9 7.6e-07 28.9 2.9 2.2 2 0 0 2 2 2 1 F-box domain adh_short_C2 PF13561.6 EGG06018.1 - 0.015 14.9 0.0 0.016 14.7 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RNase_PH_C PF03725.15 EGG06018.1 - 0.095 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 MBOAT_2 PF13813.6 EGG06019.1 - 7.8e-16 58.1 2.6 2.9e-15 56.3 2.6 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Ubie_methyltran PF01209.18 EGG06020.1 - 2.6e-75 252.7 0.0 3.2e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGG06020.1 - 2.7e-12 47.2 0.0 4.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG06020.1 - 1.9e-10 41.2 0.0 3.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG06020.1 - 1.3e-08 35.4 0.0 2.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG06020.1 - 3.3e-08 33.5 0.0 4.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGG06020.1 - 0.0079 16.1 0.0 0.099 12.5 0.0 2.3 2 0 0 2 2 2 1 Hypothetical methyltransferase LRR_8 PF13855.6 EGG06021.1 - 0.00021 21.0 0.0 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 EGG06021.1 - 0.15 12.7 0.6 20 6.3 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat Spo7 PF03907.13 EGG06023.1 - 3.1e-27 95.5 7.3 9.7e-24 84.1 3.3 2.1 1 1 1 2 2 2 2 Spo7-like protein 7tm_7 PF08395.12 EGG06023.1 - 0.0015 17.9 0.1 0.0019 17.5 0.1 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor Tmemb_18A PF09771.9 EGG06023.1 - 0.002 18.5 0.3 0.0033 17.8 0.3 1.3 1 0 0 1 1 1 1 Transmembrane protein 188 Presenilin PF01080.17 EGG06023.1 - 0.0021 16.9 0.2 0.011 14.5 0.0 1.9 2 0 0 2 2 2 1 Presenilin Ac110_PIF PF07280.11 EGG06023.1 - 5.8 6.8 6.4 1.9 8.3 1.8 2.5 2 1 0 2 2 2 0 Per os infectivity factor AC110 TMEMspv1-c74-12 PF11044.8 EGG06024.1 - 0.15 12.0 0.1 0.24 11.4 0.1 1.2 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein SMI1_KNR4 PF09346.10 EGG06025.1 - 3.1e-05 24.4 1.0 0.00041 20.8 0.0 2.7 2 1 1 3 3 3 1 SMI1 / KNR4 family (SUKH-1) Proteasome PF00227.26 EGG06026.1 - 2e-53 180.7 0.1 4.1e-53 179.7 0.0 1.5 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 EGG06026.1 - 8.2e-14 51.0 0.1 1.6e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nucleoside_tran PF01733.18 EGG06028.1 - 1.7e-32 113.0 8.4 2.6e-32 112.4 8.4 1.2 1 0 0 1 1 1 1 Nucleoside transporter CTV_P6 PF06706.11 EGG06028.1 - 0.49 10.1 4.0 5.6 6.7 0.3 2.5 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Aminotran_1_2 PF00155.21 EGG06029.1 - 2.3e-43 148.8 0.0 3.4e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGG06029.1 - 0.002 16.7 0.0 0.0035 16.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 EGG06029.1 - 0.0044 15.8 0.0 0.019 13.8 0.0 1.9 2 1 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain HK PF02110.15 EGG06030.1 - 7.3e-73 245.0 3.2 2.6e-71 239.9 3.2 2.1 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EGG06030.1 - 2.9e-51 173.4 0.1 7.3e-44 149.3 0.0 3.6 2 1 1 3 3 3 2 Thiamine monophosphate synthase Carb_kinase PF01256.17 EGG06030.1 - 0.029 13.8 0.2 0.049 13.1 0.2 1.4 1 0 0 1 1 1 0 Carbohydrate kinase SlyX PF04102.12 EGG06031.1 - 0.085 13.5 10.0 0.056 14.1 4.1 2.8 2 0 0 2 2 2 0 SlyX DUF4407 PF14362.6 EGG06031.1 - 0.44 9.8 2.7 0.86 8.9 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pro_CA PF00484.19 EGG06032.1 - 5.9e-33 114.4 0.0 8.6e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Spa1_C PF18218.1 EGG06032.1 - 0.0093 16.4 0.1 0.07 13.5 0.1 2.2 1 1 0 1 1 1 1 Lantibiotic immunity protein Spa1 C-terminal domain OTCace_N PF02729.21 EGG06032.1 - 0.017 15.1 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF2147 PF09917.9 EGG06032.1 - 0.022 15.4 0.0 0.032 14.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2147) Mic1 PF07035.12 EGG06032.1 - 0.073 12.8 0.4 2 8.1 0.1 2.2 1 1 1 2 2 2 0 Colon cancer-associated protein Mic1-like DUF2235 PF09994.9 EGG06034.1 - 4.6e-49 167.3 0.0 2.3e-48 165.0 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) CENP-R PF06729.12 EGG06035.1 - 0.013 15.4 2.3 0.013 15.4 2.3 2.2 2 1 0 2 2 2 0 Kinetochore component, CENP-R UPF0184 PF03670.13 EGG06035.1 - 0.099 13.0 5.2 0.35 11.3 2.7 3.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) PI3_PI4_kinase PF00454.27 EGG06035.1 - 0.13 12.1 0.6 0.21 11.4 0.6 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Spc7 PF08317.11 EGG06035.1 - 0.76 8.6 43.9 0.4 9.5 6.8 3.5 3 1 1 4 4 4 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 EGG06035.1 - 1 9.6 40.2 0.23 11.7 0.2 5.8 4 2 2 6 6 6 0 ABC transporter C-terminal domain AAA_13 PF13166.6 EGG06035.1 - 2.5 6.6 40.1 0.024 13.3 10.0 3.2 2 1 1 3 3 3 0 AAA domain IZUMO PF15005.6 EGG06035.1 - 5.9 7.4 7.1 30 5.1 0.0 3.0 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated AAA_27 PF13514.6 EGG06035.1 - 6.1 6.4 15.4 0.074 12.6 1.9 3.0 3 1 1 4 4 4 0 AAA domain O-FucT PF10250.9 EGG06036.1 - 5e-17 62.6 0.0 8.7e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF3160 PF11369.8 EGG06038.1 - 0.094 11.2 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) Annexin PF00191.20 EGG06039.1 - 0.052 13.6 0.2 0.16 12.0 0.2 1.8 1 0 0 1 1 1 0 Annexin UQ_con PF00179.26 EGG06041.1 - 4.2e-16 58.9 0.0 6.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 EGG06042.1 - 2.2e-73 246.9 0.0 2.6e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG06042.1 - 5.9e-34 117.5 0.0 8.2e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG06042.1 - 0.00028 19.9 0.0 0.00077 18.5 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGG06042.1 - 0.13 11.6 0.0 0.43 9.8 0.0 1.7 1 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 EGG06042.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-UBP PF02148.19 EGG06045.1 - 0.12 12.7 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein TruB_C PF09142.11 EGG06045.1 - 0.62 9.9 2.5 0.95 9.3 0.9 2.2 1 1 1 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Apolipoprotein PF01442.18 EGG06046.1 - 0.029 14.2 4.0 0.098 12.5 1.0 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain LXG PF04740.12 EGG06046.1 - 0.048 13.4 1.2 0.096 12.4 1.2 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily Focal_AT PF03623.13 EGG06046.1 - 0.067 13.2 1.7 1.7 8.7 0.6 2.5 2 0 0 2 2 2 0 Focal adhesion targeting region Baculo_PEP_C PF04513.12 EGG06046.1 - 0.14 12.2 1.5 0.34 10.9 1.5 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 EGG06046.1 - 0.21 12.2 4.7 0.54 10.9 0.3 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 EGG06046.1 - 0.79 9.7 5.1 3.2 7.8 0.7 2.8 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) EF1G PF00647.19 EGG06047.1 - 1.3e-39 134.5 0.3 3.1e-39 133.3 0.3 1.7 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EGG06047.1 - 4e-12 46.3 0.0 1e-11 45.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG06047.1 - 1.5e-11 44.3 0.0 1.5e-11 44.3 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG06047.1 - 2.8e-10 40.1 0.5 6.9e-10 38.8 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGG06047.1 - 2.8e-07 30.8 0.0 5.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGG06047.1 - 3.2e-06 27.3 0.1 1.1e-05 25.5 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGG06047.1 - 0.038 13.8 0.5 0.24 11.2 0.1 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain zf-RING_2 PF13639.6 EGG06048.1 - 0.79 10.1 3.3 55 4.2 3.3 2.7 1 1 0 1 1 1 0 Ring finger domain ERCC3_RAD25_C PF16203.5 EGG06049.1 - 0.15 11.2 0.0 0.34 10.1 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Cofilin_ADF PF00241.20 EGG06050.1 - 1.1e-36 125.3 0.0 1.2e-17 63.9 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein CAP PF00188.26 EGG06051.1 - 5.7e-16 59.5 0.3 1.7e-15 57.9 0.3 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family DUF3362 PF11842.8 EGG06051.1 - 0.017 15.5 0.1 0.025 14.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) DUF3430 PF11912.8 EGG06051.1 - 0.042 13.9 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) CAP PF00188.26 EGG06052.1 - 3.3e-14 53.8 2.1 2.6e-13 50.9 1.0 2.4 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Transpos_assoc PF13963.6 EGG06052.1 - 0.56 10.6 3.9 2.6 8.4 0.1 2.7 3 0 0 3 3 3 0 Transposase-associated domain CAP PF00188.26 EGG06053.1 - 4.6e-14 53.3 0.1 1.2e-13 51.9 0.1 1.7 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 EGG06054.1 - 1.8e-14 54.7 0.6 1.8e-13 51.4 0.6 2.1 1 1 0 1 1 1 1 Cysteine-rich secretory protein family HAMP PF00672.25 EGG06055.1 - 6.5e-41 138.5 15.9 3.3e-07 30.6 0.0 7.4 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.26 EGG06055.1 - 7.9e-29 100.4 0.0 3.3e-28 98.4 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGG06055.1 - 5.6e-27 94.1 0.8 6.3e-26 90.7 0.4 2.9 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 EGG06055.1 - 4.8e-18 65.0 0.6 4.2e-17 62.0 0.6 2.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF4795 PF16043.5 EGG06055.1 - 0.0021 17.7 2.9 4 7.0 0.1 4.0 3 1 1 4 4 4 2 Domain of unknown function (DUF4795) Rhabdo_NV PF02484.15 EGG06055.1 - 0.0054 16.9 3.1 5 7.3 0.0 4.9 4 1 1 5 5 5 1 Rhabdovirus Non-virion protein GatB_Yqey PF02637.18 EGG06055.1 - 0.057 13.3 3.7 1.5 8.7 0.0 3.7 4 0 0 4 4 4 0 GatB domain DUF3829 PF12889.7 EGG06055.1 - 0.59 9.6 2.3 32 3.9 0.0 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF3829) DUF1045 PF06299.12 EGG06055.1 - 1.1 9.2 3.9 2 8.4 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1045) zf-H2C2_2 PF13465.6 EGG06058.1 - 1.1e-05 25.6 1.4 1.4e-05 25.3 0.1 1.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGG06058.1 - 0.0062 16.9 0.2 0.0062 16.9 0.2 3.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG06058.1 - 0.33 11.9 0.2 0.33 11.9 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger DnaJ_C PF01556.18 EGG06059.1 - 2.3e-37 128.4 0.4 3.1e-37 127.9 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGG06059.1 - 7e-22 77.3 0.7 1.2e-21 76.6 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGG06059.1 - 1.2e-15 57.6 16.2 2.3e-15 56.7 16.2 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGG06059.1 - 0.0098 15.8 8.9 0.6 10.1 0.9 2.7 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGG06059.1 - 5.9 6.9 11.2 13 5.9 1.2 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ion_trans PF00520.31 EGG06060.1 - 1.9e-116 387.6 97.1 9.4e-43 146.2 13.0 4.9 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.32 EGG06060.1 - 0.087 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 EF hand Phage_holin_6_1 PF09682.10 EGG06062.1 - 0.11 13.0 4.7 0.23 11.9 4.7 1.6 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF2040 PF09745.9 EGG06066.1 - 1.1e-34 119.1 14.4 1.1e-34 119.1 14.4 3.2 2 2 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF2315 PF10231.9 EGG06066.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.4 2 1 0 2 2 2 0 Apoptogenic protein 1 DUF1179 PF06678.11 EGG06066.1 - 0.86 9.6 4.7 1 9.4 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) GATA PF00320.27 EGG06068.1 - 3.6e-10 39.3 0.5 3.6e-10 39.3 0.5 1.6 2 0 0 2 2 2 1 GATA zinc finger OTT_1508_deam PF14441.6 EGG06068.1 - 0.16 12.0 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 OTT_1508-like deaminase Copper-fist PF00649.18 EGG06069.1 - 4.9e-18 64.3 2.4 4.9e-18 64.3 2.4 2.2 1 1 1 2 2 2 1 Copper fist DNA binding domain DUF3716 PF12511.8 EGG06069.1 - 0.5 10.4 10.7 1.7 8.8 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Med7 PF05983.11 EGG06071.1 - 8.9e-41 140.1 3.2 1.3e-40 139.6 3.2 1.2 1 0 0 1 1 1 1 MED7 protein DUF676 PF05057.14 EGG06072.1 - 5.3e-06 26.1 0.0 1.4e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGG06072.1 - 7.9e-05 22.6 0.0 0.00029 20.8 0.0 1.9 2 0 0 2 2 2 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGG06072.1 - 0.0038 17.0 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein eIF3g PF12353.8 EGG06073.1 - 2.1e-38 131.6 0.2 3.5e-38 130.8 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EGG06073.1 - 1.3e-17 63.4 0.0 2.5e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG06073.1 - 0.0057 16.6 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EGG06073.1 - 0.038 13.6 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 3-HAO PF06052.12 EGG06074.1 - 1.8e-54 183.5 0.0 2.2e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EGG06074.1 - 1.6e-05 24.5 0.0 2.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EGG06074.1 - 9.6e-05 22.0 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 EGG06074.1 - 0.0083 16.3 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Pkinase PF00069.25 EGG06077.1 - 1.3e-65 221.4 1.6 2.2e-65 220.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG06077.1 - 3.6e-31 108.4 0.5 2.5e-30 105.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGG06077.1 - 6.7e-09 36.3 1.9 6.7e-09 36.3 1.9 2.9 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 EGG06077.1 - 3e-07 30.7 0.1 0.0011 19.2 0.1 2.7 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 EGG06077.1 - 7e-06 25.6 0.1 6.8e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EGG06077.1 - 0.014 15.0 3.4 0.12 12.0 0.2 2.9 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGG06077.1 - 0.03 13.7 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_4 PF14570.6 EGG06078.1 - 1.5e-21 75.9 12.4 2.4e-21 75.2 12.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EGG06078.1 - 1.7e-06 27.8 7.6 2.7e-06 27.1 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG06078.1 - 0.011 15.6 4.5 0.011 15.6 4.5 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 EGG06078.1 - 0.033 14.3 3.2 0.067 13.3 3.2 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_2 PF13639.6 EGG06078.1 - 0.08 13.3 12.0 0.14 12.5 12.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 EGG06078.1 - 0.14 12.1 10.7 0.24 11.3 10.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 EGG06078.1 - 0.53 10.2 2.7 1.1 9.3 2.7 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 EGG06078.1 - 0.58 10.1 10.0 1 9.3 10.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG06078.1 - 1.4 9.0 8.9 3.7 7.7 8.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DNA_pol_phi PF04931.13 EGG06080.1 - 6.8e-114 381.6 8.8 6.8e-114 381.6 8.8 3.1 1 1 0 2 2 2 1 DNA polymerase phi CARD_2 PF16739.5 EGG06080.1 - 0.017 15.1 1.6 0.11 12.4 0.0 3.1 3 0 0 3 3 3 0 Caspase recruitment domain GET2 PF08690.10 EGG06086.1 - 0.014 15.1 1.3 0.014 15.1 1.3 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 Alpha_kinase PF02816.18 EGG06088.1 - 2e-19 70.4 0.1 3e-19 69.9 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family ABC_tran_CTD PF16326.5 EGG06091.1 - 0.0032 17.7 1.7 0.25 11.6 0.1 2.3 2 0 0 2 2 2 1 ABC transporter C-terminal domain Translin PF01997.16 EGG06091.1 - 0.05 13.6 0.5 0.079 12.9 0.5 1.3 1 0 0 1 1 1 0 Translin family SlyX PF04102.12 EGG06091.1 - 0.077 13.6 0.1 10 6.8 0.0 2.5 2 0 0 2 2 2 0 SlyX COG5 PF10392.9 EGG06091.1 - 0.099 12.8 2.9 0.26 11.5 0.8 2.3 1 1 0 2 2 2 0 Golgi transport complex subunit 5 KxDL PF10241.9 EGG06091.1 - 0.11 12.8 2.0 5.8 7.3 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein K-box PF01486.17 EGG06091.1 - 0.17 12.1 2.0 7 6.9 0.6 2.4 2 0 0 2 2 2 0 K-box region FlaC_arch PF05377.11 EGG06091.1 - 0.73 10.3 3.2 7.8 7.0 0.1 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Sugarporin_N PF11471.8 EGG06091.1 - 0.83 9.7 3.4 0.32 11.0 0.4 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension TRAF_BIRC3_bd PF16673.5 EGG06092.1 - 0.0038 17.0 0.7 0.008 15.9 0.7 1.6 1 0 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain Med8 PF10232.9 EGG06092.1 - 0.047 13.3 2.8 0.13 11.9 2.9 1.5 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Abi_C PF14355.6 EGG06092.1 - 0.077 13.1 0.2 0.16 12.1 0.2 1.6 1 0 0 1 1 1 0 Abortive infection C-terminus TssO PF17561.2 EGG06092.1 - 0.15 12.2 4.9 0.18 11.9 3.7 1.6 1 1 1 2 2 2 0 Type VI secretion system, TssO zf-CCHC PF00098.23 EGG06093.1 - 0.04 14.0 1.0 0.089 12.9 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle MLVIN_C PF18697.1 EGG06094.1 - 0.0044 17.1 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain LOH1CR12 PF10158.9 EGG06096.1 - 0.02 14.9 0.2 0.045 13.8 0.2 1.5 1 0 0 1 1 1 0 Tumour suppressor protein DUF1664 PF07889.12 EGG06096.1 - 0.027 14.5 0.6 0.043 13.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FemAB_like PF04339.12 EGG06097.1 - 0.077 12.1 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition PQ-loop PF04193.14 EGG06099.1 - 6.7e-32 109.1 17.2 2e-17 62.7 2.3 3.3 3 0 0 3 3 3 2 PQ loop repeat DUF963 PF06131.11 EGG06099.1 - 0.1 12.0 0.3 0.19 11.1 0.3 1.4 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) zf-C2HE PF16278.5 EGG06100.1 - 6e-13 49.0 0.4 6e-13 49.0 0.4 1.5 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger Phage_TTP_11 PF16460.5 EGG06101.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube, TTP, lambda-like bVLRF1 PF18826.1 EGG06102.1 - 2.5e-09 37.2 0.0 4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Kinesin PF00225.23 EGG06104.1 - 9.4e-111 369.9 0.0 2.7e-110 368.4 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGG06104.1 - 3.2e-25 88.8 0.0 1.2e-24 87.0 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding WD40 PF00400.32 EGG06105.1 - 2.4e-13 50.3 4.7 0.092 13.7 0.0 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG06105.1 - 1.4e-11 44.5 1.0 3.9e-06 27.1 0.0 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG06105.1 - 1.1e-09 37.7 1.3 7.7e-05 21.8 0.1 3.7 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGG06105.1 - 5.6e-06 26.4 0.1 0.0085 16.0 0.1 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EGG06105.1 - 0.031 12.8 0.3 0.075 11.5 0.1 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF5556 PF17711.1 EGG06106.1 - 0.011 15.6 0.1 0.4 10.6 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5556) CmcI PF04989.12 EGG06106.1 - 0.028 14.1 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase SURF6 PF04935.12 EGG06108.1 - 7.8e-45 153.1 58.5 7.8e-45 153.1 58.5 3.2 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 EGG06108.1 - 1.3e-13 51.3 0.9 1.3e-13 51.3 0.9 5.6 4 2 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 Zn_clus PF00172.18 EGG06109.1 - 6.8e-08 32.5 7.9 1.2e-07 31.7 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EGG06111.1 - 1.6e-59 201.4 0.0 2.1e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG06111.1 - 4.2e-23 82.0 0.0 6.2e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG06111.1 - 0.00014 21.9 0.3 0.2 11.5 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG06111.1 - 0.00017 21.0 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGG06111.1 - 0.051 13.2 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EGG06111.1 - 0.053 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_S8e PF01201.22 EGG06112.1 - 7.4e-40 136.3 2.8 8.4e-40 136.1 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Alpha_kinase PF02816.18 EGG06113.1 - 4.1e-21 76.0 0.0 5.3e-20 72.3 0.0 2.6 2 1 1 3 3 3 1 Alpha-kinase family Nitrate_red_gam PF02665.14 EGG06115.1 - 0.078 12.5 0.0 0.082 12.4 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit OTU PF02338.19 EGG06117.1 - 7.3e-24 84.7 0.0 1.3e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGG06117.1 - 0.0079 15.7 0.0 0.41 10.1 0.0 2.7 3 0 0 3 3 3 1 Peptidase C65 Otubain YihI PF04220.12 EGG06117.1 - 0.033 13.9 2.9 0.039 13.7 1.4 1.8 2 0 0 2 2 2 0 Der GTPase activator (YihI) DUF1664 PF07889.12 EGG06117.1 - 0.19 11.8 0.2 0.35 10.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LegC3_N PF18654.1 EGG06117.1 - 0.24 10.6 9.4 0.6 9.3 9.5 1.6 1 1 0 1 1 1 0 LegC3 N-terminal coiled-coil domain DUF35_N PF12172.8 EGG06119.1 - 0.15 11.9 3.2 3.1 7.7 0.6 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FKS1_dom1 PF14288.6 EGG06121.1 - 0.0062 16.9 1.0 0.026 14.9 0.1 2.4 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 GCFC PF07842.12 EGG06122.1 - 1.6e-56 191.9 14.2 2.7e-56 191.2 14.2 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EGG06122.1 - 6.8e-15 54.7 3.9 2.1e-14 53.1 3.9 1.9 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 EGG06122.1 - 2.2e-05 24.8 13.5 2.2e-05 24.8 13.5 3.4 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 EGG06122.1 - 0.0001 22.3 1.4 0.0001 22.3 1.4 3.0 3 0 0 3 3 3 1 G-patch domain DUF1910 PF08928.10 EGG06122.1 - 0.037 14.0 0.8 0.13 12.3 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) LAP1C PF05609.12 EGG06122.1 - 1.3 8.1 11.4 0.5 9.4 2.0 2.5 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Col_cuticle_N PF01484.17 EGG06124.1 - 0.0053 16.8 0.1 0.008 16.2 0.1 1.3 1 0 0 1 1 1 1 Nematode cuticle collagen N-terminal domain LapA_dom PF06305.11 EGG06124.1 - 0.066 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SRF-TF PF00319.18 EGG06126.1 - 7.9e-18 63.7 0.0 1.4e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) RTP1_C1 PF10363.9 EGG06127.1 - 3.2e-27 94.9 0.6 1.8e-26 92.5 0.3 2.5 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EGG06127.1 - 0.00059 19.5 0.2 0.0014 18.3 0.2 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 Sec7_N PF12783.7 EGG06127.1 - 0.014 15.3 9.1 0.13 12.1 0.1 3.5 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RRM_1 PF00076.22 EGG06128.1 - 6.3e-18 64.4 0.0 8.7e-18 63.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG06128.1 - 4.4e-05 23.5 0.0 8.2e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif Myb_DNA-binding PF00249.31 EGG06132.1 - 0.021 15.0 0.0 0.19 11.9 0.1 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Abhydrolase_2 PF02230.16 EGG06133.1 - 1.5e-27 96.8 0.1 1.5e-26 93.6 0.1 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGG06133.1 - 0.00021 21.0 0.0 0.00036 20.2 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Patatin PF01734.22 EGG06133.1 - 0.029 14.6 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase HgmA PF04209.13 EGG06134.1 - 2.5e-138 461.3 0.0 3.1e-138 461.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Pkinase PF00069.25 EGG06135.1 - 1e-25 90.6 0.0 1.2e-25 90.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG06135.1 - 2.6e-15 56.4 0.0 3.3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG06135.1 - 0.0044 16.0 0.1 0.011 14.6 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGG06135.1 - 0.0068 15.8 0.0 0.0094 15.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG06135.1 - 0.007 15.7 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG06135.1 - 0.0094 15.9 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-U1 PF06220.12 EGG06136.1 - 5.4e-19 67.7 1.9 8e-19 67.1 1.9 1.3 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 EGG06136.1 - 2.7 8.0 7.0 4.9 7.1 7.0 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle Hus1 PF04005.12 EGG06137.1 - 9.6e-43 146.4 0.0 1.2e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein fn3_2 PF16893.5 EGG06138.1 - 1.5e-37 127.6 0.2 2.6e-37 126.8 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EGG06138.1 - 4.6e-17 61.7 0.3 7.7e-17 61.0 0.3 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 EGG06138.1 - 7.6e-10 39.0 0.0 1.8e-09 37.8 0.0 1.7 1 1 1 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGG06138.1 - 7e-06 25.9 0.0 5.1e-05 23.1 0.0 2.4 2 1 0 2 2 2 1 twin BRCT domain BRCT_3 PF18428.1 EGG06138.1 - 0.00026 21.0 0.2 0.00097 19.2 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGG06138.1 - 0.0029 18.0 0.0 0.0063 16.9 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 EGG06138.1 - 0.07 13.5 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 Fibronectin type III domain DUF3006 PF11213.8 EGG06138.1 - 0.22 11.8 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) P21-Arc PF04062.14 EGG06139.1 - 2.4e-67 226.3 0.0 2.7e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit TPR_1 PF00515.28 EGG06142.1 - 6.7e-08 32.0 0.0 0.00014 21.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG06142.1 - 1.6e-05 24.6 0.1 0.016 15.3 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3535 PF12054.8 EGG06142.1 - 0.0014 17.9 1.1 0.0029 16.9 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) DnaJ PF00226.31 EGG06142.1 - 0.0017 18.4 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain HTH_Tnp_Tc3_2 PF01498.18 EGG06142.1 - 0.05 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Transposase ArsR PF09824.9 EGG06142.1 - 0.19 11.3 4.1 0.063 12.9 0.4 2.2 3 0 0 3 3 3 0 ArsR transcriptional regulator Methyltransf_16 PF10294.9 EGG06143.1 - 1.2e-14 54.4 0.2 2.6e-14 53.3 0.2 1.5 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGG06143.1 - 0.00099 19.0 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 EGG06143.1 - 0.0014 18.4 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_12 PF08242.12 EGG06143.1 - 0.028 15.1 0.0 0.15 12.8 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 EGG06143.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 EGG06143.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Dynamitin PF04912.14 EGG06145.1 - 9.4e-69 232.6 23.7 1.5e-51 175.9 13.1 2.1 2 0 0 2 2 2 2 Dynamitin PspB PF06667.12 EGG06145.1 - 1.4 9.0 8.5 6.2 7.0 0.8 3.4 3 0 0 3 3 3 0 Phage shock protein B GIDA_assoc PF13932.6 EGG06145.1 - 1.5 9.0 0.0 1.5 9.0 0.0 2.9 3 0 0 3 3 3 0 GidA associated domain Baculo_PEP_C PF04513.12 EGG06145.1 - 1.6 8.8 17.7 0.31 11.1 0.4 3.9 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EGG06145.1 - 4.5 6.1 22.9 0.03 13.2 2.1 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein CCDC84 PF14968.6 EGG06147.1 - 0.42 10.2 5.9 0.17 11.5 0.4 2.1 2 0 0 2 2 2 0 Coiled coil protein 84 Steroid_dh PF02544.16 EGG06148.1 - 1e-29 103.5 2.0 1e-29 103.5 2.0 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 EGG06148.1 - 0.0013 18.5 0.2 0.0039 16.9 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin family DUF1295 PF06966.12 EGG06148.1 - 0.0014 18.2 1.7 0.0021 17.6 0.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Ubiquitin_4 PF18036.1 EGG06148.1 - 0.043 13.9 3.7 1.2 9.2 1.6 2.7 2 1 0 2 2 2 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 EGG06148.1 - 0.22 12.0 1.8 0.72 10.3 1.9 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain TPR_1 PF00515.28 EGG06150.1 - 4e-09 35.9 2.2 0.025 14.4 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG06150.1 - 1.9e-07 30.6 2.8 0.061 13.5 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG06150.1 - 0.0033 17.5 0.3 0.74 10.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG06150.1 - 0.0038 17.5 1.2 0.053 13.8 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG06150.1 - 0.0076 16.6 0.1 14 6.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG06150.1 - 0.024 14.7 0.3 2.1 8.6 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGG06150.1 - 0.044 13.9 0.3 0.18 12.0 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGG06150.1 - 0.058 13.4 2.7 5.2 7.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGG06150.1 - 1.5 8.8 4.5 4.3 7.3 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat RWD PF05773.22 EGG06152.1 - 0.032 14.5 0.1 0.032 14.5 0.1 2.1 2 1 0 2 2 2 0 RWD domain UvrD-helicase PF00580.21 EGG06154.1 - 3.7e-48 164.7 0.0 1.6e-47 162.6 0.0 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EGG06154.1 - 2.7e-47 161.8 0.0 5.6e-47 160.8 0.0 1.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EGG06154.1 - 2.5e-22 79.8 0.0 6.6e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGG06154.1 - 2.4e-12 46.5 0.2 1.5e-11 43.9 0.0 2.5 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 EGG06154.1 - 0.023 14.3 0.0 0.097 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EGG06154.1 - 0.05 13.3 0.0 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase NDK PF00334.19 EGG06157.1 - 2e-48 163.8 0.0 2.6e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase GFRP PF06399.13 EGG06157.1 - 0.15 11.9 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Cation_efflux PF01545.21 EGG06158.1 - 2.7e-46 157.8 1.1 4.4e-46 157.1 1.1 1.3 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGG06158.1 - 0.054 13.6 0.4 0.11 12.6 0.4 1.4 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter SET PF00856.28 EGG06161.1 - 9.8e-09 35.8 0.0 2e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 SET domain FAM178 PF14816.6 EGG06161.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 Peroxidase_2 PF01328.17 EGG06162.1 - 1.3e-29 104.0 0.0 1.8e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 SLBB PF10531.9 EGG06164.1 - 0.058 13.3 0.1 7.5 6.5 0.0 2.2 2 0 0 2 2 2 0 SLBB domain DUF2992 PF11208.8 EGG06165.1 - 0.46 10.7 7.5 0.52 10.6 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Wound_ind PF08186.11 EGG06165.1 - 4.9 7.7 6.0 9.9 6.7 0.2 2.2 2 0 0 2 2 2 0 Wound-inducible basic protein family Peptidase_C97 PF05903.14 EGG06166.1 - 0.037 13.8 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 PPPDE putative peptidase domain SDA1 PF05285.12 EGG06167.1 - 0.034 13.6 6.1 0.052 13.0 6.1 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGG06167.1 - 0.54 8.4 9.8 0.78 7.9 9.8 1.2 1 0 0 1 1 1 0 Nop14-like family XAP5 PF04921.14 EGG06167.1 - 1 9.1 5.1 2.1 8.1 5.1 1.5 1 0 0 1 1 1 0 XAP5, circadian clock regulator CDC45 PF02724.14 EGG06167.1 - 1.3 7.2 6.5 2.1 6.6 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 EGG06167.1 - 2 8.6 6.0 0.68 10.1 2.1 2.0 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal NOA36 PF06524.12 EGG06167.1 - 3.7 6.8 13.7 7.6 5.8 13.7 1.6 1 0 0 1 1 1 0 NOA36 protein MoCF_biosynth PF00994.24 EGG06168.1 - 5.9e-38 129.8 0.0 3.5e-18 65.6 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EGG06168.1 - 5.5e-31 107.4 0.0 1.1e-30 106.5 0.0 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EGG06168.1 - 2.5e-07 30.7 0.0 5.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Tim54 PF11711.8 EGG06168.1 - 0.8 8.4 3.7 1.4 7.6 3.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 LPP PF04728.13 EGG06170.1 - 0.0017 18.7 3.7 0.09 13.2 0.1 3.2 2 1 1 3 3 3 1 Lipoprotein leucine-zipper DUF4618 PF15397.6 EGG06170.1 - 0.0055 16.2 3.4 0.0055 16.2 3.4 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4618) HR1 PF02185.16 EGG06170.1 - 0.0071 16.4 1.8 0.027 14.6 1.8 1.9 1 0 0 1 1 1 1 Hr1 repeat Cep57_MT_bd PF06657.13 EGG06170.1 - 0.0073 16.7 7.4 1.1 9.7 6.2 3.5 2 1 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Gp-FAR-1 PF05823.12 EGG06170.1 - 0.029 14.7 2.1 0.059 13.7 1.8 1.7 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) HOOK PF05622.12 EGG06170.1 - 0.068 11.3 14.4 0.0096 14.1 10.6 1.5 2 0 0 2 2 2 0 HOOK protein KASH_CCD PF14662.6 EGG06170.1 - 0.27 11.0 12.2 0.62 9.9 12.2 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF16 PF01519.16 EGG06170.1 - 0.46 11.0 11.5 4.9 7.7 4.0 3.4 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF948 PF06103.11 EGG06170.1 - 0.46 10.8 6.8 4.4 7.6 0.8 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) CLZ PF16526.5 EGG06170.1 - 0.54 10.7 10.2 0.4 11.1 2.7 3.3 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Vac_Fusion PF02346.16 EGG06170.1 - 0.9 9.2 3.0 4.2 7.1 0.1 3.4 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 YabA PF06156.13 EGG06170.1 - 0.93 10.2 12.0 2 9.1 7.6 3.1 2 1 0 2 2 2 0 Initiation control protein YabA BLOC1_2 PF10046.9 EGG06170.1 - 1.6 9.1 10.5 3.2 8.1 1.4 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Golgin_A5 PF09787.9 EGG06170.1 - 1.7 8.1 15.8 0.57 9.6 12.9 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 YlqD PF11068.8 EGG06170.1 - 2.1 8.7 13.5 1.1 9.6 9.3 2.4 2 0 0 2 2 2 0 YlqD protein ATG16 PF08614.11 EGG06170.1 - 2.4 8.3 17.9 0.84 9.8 12.4 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 EGG06170.1 - 3.8 8.0 5.5 42 4.7 0.1 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 EGG06170.1 - 3.8 7.5 16.4 5 7.2 12.7 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CdvA PF18822.1 EGG06170.1 - 4.5 7.1 9.3 13 5.6 1.2 3.0 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Seryl_tRNA_N PF02403.22 EGG06170.1 - 4.8 7.5 7.8 3.5 7.9 3.0 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 EGG06170.1 - 6.1 7.3 11.6 2.2 8.8 1.2 3.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) IFT20 PF14931.6 EGG06170.1 - 7.6 6.7 11.7 20 5.4 4.9 3.4 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 CASP_C PF08172.12 EGG06170.1 - 8.5 5.6 12.7 1.6 8.0 4.7 2.8 2 1 1 3 3 3 0 CASP C terminal TolA_bind_tri PF16331.5 EGG06170.1 - 9.5 6.4 14.2 0.16 12.1 6.4 2.2 3 0 0 3 3 2 0 TolA binding protein trimerisation Glyco_hydro_26 PF02156.15 EGG06174.1 - 0.001 18.6 1.2 0.0026 17.3 0.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 26 ADH_zinc_N_2 PF13602.6 EGG06177.1 - 0.00024 22.1 0.0 0.00045 21.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGG06177.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase PF00069.25 EGG06178.1 - 5.8e-47 160.3 0.0 6.7e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG06178.1 - 2.9e-29 102.2 0.0 3.5e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGG06178.1 - 1.9e-06 27.4 0.1 2.7e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGG06178.1 - 0.0044 16.0 0.9 0.0075 15.3 0.9 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGG06178.1 - 0.011 14.8 0.3 0.018 14.1 0.3 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EGG06178.1 - 0.024 14.5 0.1 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG06178.1 - 0.027 13.8 0.6 0.28 10.4 0.6 2.1 1 1 0 1 1 1 0 Kinase-like Viral_P18 PF04521.13 EGG06181.1 - 0.18 11.6 4.2 0.075 12.8 0.5 2.2 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein EOS1 PF12326.8 EGG06181.1 - 1.1 9.2 2.9 2 8.3 2.9 1.5 1 0 0 1 1 1 0 N-glycosylation protein Zip PF02535.22 EGG06181.1 - 2.7 7.1 4.7 3.9 6.6 4.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 EGG06181.1 - 4.9 6.9 15.0 1.2 8.9 12.0 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Peroxidase_2 PF01328.17 EGG06182.1 - 2.7e-34 119.4 0.0 3.6e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Integrase_Zn PF02022.19 EGG06182.1 - 0.16 11.9 0.3 3.3 7.7 0.1 2.3 2 0 0 2 2 2 0 Integrase Zinc binding domain Sec3_C PF09763.9 EGG06183.1 - 0.29 9.5 6.1 0.31 9.4 6.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 RAP1 PF07218.11 EGG06183.1 - 0.53 8.5 4.0 0.6 8.3 4.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ubiquitin PF00240.23 EGG06184.1 - 1.2e-32 111.5 0.4 1.2e-32 111.5 0.4 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 EGG06184.1 - 4e-27 94.1 1.3 4e-27 94.1 1.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EGG06184.1 - 1.6e-16 59.9 0.6 3.2e-16 58.9 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGG06184.1 - 6.3e-05 23.3 0.3 0.00034 21.0 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGG06184.1 - 0.00068 19.7 0.7 0.0016 18.6 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGG06184.1 - 0.005 17.2 1.4 0.0065 16.8 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGG06184.1 - 0.0068 16.3 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EGG06184.1 - 0.0079 16.7 0.7 0.011 16.3 0.7 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGG06184.1 - 0.032 14.3 0.4 9.4 6.4 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4925 PF16272.5 EGG06184.1 - 0.05 13.1 0.1 0.059 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4925) CxC1 PF18802.1 EGG06187.1 - 1.6e-29 102.1 0.1 2.6e-29 101.4 0.1 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG06187.1 - 9.7e-10 38.6 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG06187.1 - 0.042 13.7 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases MaoC_dehydratas PF01575.19 EGG06188.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain DUF1365 PF07103.11 EGG06189.1 - 1.8e-34 119.4 0.5 2.2e-34 119.2 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) FAD_binding_3 PF01494.19 EGG06190.1 - 4.6e-77 259.6 0.0 5.7e-76 256.0 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGG06190.1 - 7.4e-45 153.0 0.0 1.5e-44 152.0 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 EGG06190.1 - 8.2e-05 22.8 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGG06190.1 - 0.00012 21.4 0.3 0.00017 20.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGG06190.1 - 0.00036 19.4 0.2 0.00051 18.8 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein ThiF PF00899.21 EGG06190.1 - 0.00041 19.8 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family Pyr_redox_3 PF13738.6 EGG06190.1 - 0.00082 18.7 0.1 0.0012 18.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGG06190.1 - 0.0011 18.3 0.1 0.003 16.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGG06190.1 - 0.0019 17.9 0.1 0.0031 17.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGG06190.1 - 0.0025 17.1 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 EGG06190.1 - 0.0041 16.0 0.1 0.0057 15.6 0.1 1.1 1 0 0 1 1 1 1 Tryptophan halogenase AlaDh_PNT_C PF01262.21 EGG06190.1 - 0.018 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EGG06190.1 - 0.019 14.0 1.6 0.045 12.8 1.3 1.6 1 1 1 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EGG06190.1 - 0.033 13.2 0.1 0.054 12.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 EGG06190.1 - 0.035 13.5 0.3 0.048 13.0 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 EGG06190.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 EGG06190.1 - 0.067 13.3 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EGG06190.1 - 0.13 12.8 0.2 0.32 11.6 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG06190.1 - 0.18 11.8 0.1 0.46 10.5 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding PHD PF00628.29 EGG06194.1 - 1.4e-06 28.1 10.0 2.5e-06 27.2 10.0 1.5 1 0 0 1 1 1 1 PHD-finger NUC153 PF08159.12 EGG06194.1 - 0.2 11.5 0.5 0.57 10.0 0.1 2.0 2 0 0 2 2 2 0 NUC153 domain MMR_HSR1_Xtn PF16897.5 EGG06195.1 - 4.5e-41 139.2 0.1 1.2e-40 137.8 0.1 1.8 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EGG06195.1 - 5.9e-20 71.5 0.0 1.4e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EGG06195.1 - 5.3e-17 61.6 0.1 1.1e-16 60.7 0.1 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EGG06195.1 - 1.1e-08 34.8 0.2 2.2e-08 33.8 0.1 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B zf-C2H2 PF00096.26 EGG06198.1 - 4.7e-11 42.5 30.6 8.4e-05 22.8 1.5 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG06198.1 - 1.9e-07 31.3 29.1 0.016 16.0 1.4 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EGG06198.1 - 2.3e-05 25.1 13.2 0.014 16.1 1.3 4.0 2 2 1 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_12 PF18658.1 EGG06198.1 - 0.038 13.6 3.6 0.37 10.4 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 EGG06198.1 - 0.052 13.9 13.1 0.5 10.7 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG06198.1 - 0.13 12.7 14.6 2.8 8.4 0.3 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF2256 PF10013.9 EGG06198.1 - 0.21 11.7 14.7 0.55 10.4 0.0 4.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_ZIC PF18366.1 EGG06198.1 - 0.33 11.1 8.7 0.35 11.0 0.3 3.4 3 1 0 3 3 3 0 Zic proteins zinc finger domain zf-H2C2_5 PF13909.6 EGG06198.1 - 0.48 10.2 5.6 2.7 7.8 1.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PDE8 PF08629.10 EGG06198.1 - 1.4 9.0 5.5 4.5 7.3 1.1 2.9 2 0 0 2 2 2 0 PDE8 phosphodiesterase C5HCH PF17982.1 EGG06198.1 - 3.4 7.9 16.4 0.16 12.1 0.3 4.4 4 1 1 5 5 5 0 NSD Cys-His rich domain zf-BED PF02892.15 EGG06198.1 - 5.3 7.1 22.0 9.5 6.3 7.2 4.4 2 2 1 3 3 3 0 BED zinc finger IL3 PF02059.15 EGG06199.1 - 0.0068 16.5 0.0 2.9 8.0 0.0 2.6 2 0 0 2 2 2 2 Interleukin-3 DUF1911 PF08929.10 EGG06199.1 - 0.11 13.3 2.1 0.15 12.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) Trypan_PARP PF05887.11 EGG06201.1 - 0.77 9.7 4.4 0.93 9.5 4.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PQQ PF01011.21 EGG06202.1 - 0.043 13.8 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 PQQ enzyme repeat Pro_isomerase PF00160.21 EGG06204.1 - 1.7e-45 155.1 0.1 2e-45 154.9 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF19 PF01579.18 EGG06205.1 - 0.067 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF19) EspA PF03433.13 EGG06206.1 - 0.085 12.7 0.2 0.7 9.7 0.2 2.3 2 0 0 2 2 2 0 EspA-like secreted protein DUF2247 PF10004.9 EGG06207.1 - 0.047 13.5 0.3 0.047 13.5 0.3 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2247) IZUMO PF15005.6 EGG06207.1 - 0.07 13.7 0.3 0.35 11.4 0.1 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Spc7 PF08317.11 EGG06208.1 - 0.0081 15.1 0.1 0.019 13.9 0.1 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein NPV_P10 PF05531.12 EGG06208.1 - 0.0091 16.4 1.0 0.053 14.0 1.0 2.1 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EGG06208.1 - 0.01 15.9 2.9 0.017 15.2 2.9 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 EGG06208.1 - 0.03 14.4 0.4 0.059 13.5 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 EGG06208.1 - 0.051 13.6 0.5 0.09 12.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LIF_OSM PF01291.17 EGG06208.1 - 0.059 13.5 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 LIF / OSM family Helo_like_N PF17111.5 EGG06208.1 - 0.072 12.4 1.1 0.48 9.8 0.7 2.1 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins ERM PF00769.19 EGG06208.1 - 0.13 12.0 0.5 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EGG06208.1 - 0.13 12.3 1.5 0.57 10.3 0.6 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain UPF0137 PF03677.13 EGG06210.1 - 0.061 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Lactonase PF10282.9 EGG06211.1 - 3.8e-61 207.2 0.7 4.6e-61 207.0 0.7 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Lactonase PF10282.9 EGG06212.1 - 7.5e-58 196.4 0.3 5e-53 180.5 0.3 2.0 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller DUF4632 PF15451.6 EGG06213.1 - 0.6 10.2 1.7 0.99 9.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) VPS9 PF02204.18 EGG06214.1 - 6.7e-15 55.2 0.0 7.2e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF1529 PF07485.11 EGG06215.1 - 0.054 13.4 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) MFS_1 PF07690.16 EGG06217.1 - 3.5e-19 68.9 21.1 1.3e-14 54.0 3.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EGG06218.1 - 9.3e-36 123.5 29.9 1.5e-35 122.8 28.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EGG06218.1 - 0.00074 18.5 10.2 0.041 12.7 0.3 2.3 2 0 0 2 2 2 2 MFS_1 like family ECR1_N PF14382.6 EGG06219.1 - 2.3e-13 49.7 0.0 3.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EGG06219.1 - 2.5e-13 50.1 0.1 5.2e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 KH domain PIN7 PF18475.1 EGG06223.1 - 0.071 13.7 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 PIN domain RNase_H PF00075.24 EGG06224.1 - 6.3e-08 32.9 0.0 7.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 RNase H IF4E PF01652.18 EGG06225.1 - 3e-41 140.9 0.0 3.3e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Rep-A_N PF04057.12 EGG06226.1 - 2.6e-25 88.3 0.0 3.4e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain Vps39_2 PF10367.9 EGG06226.1 - 0.11 13.0 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Myb_DNA-bind_3 PF12776.7 EGG06228.1 - 4.7e-05 24.3 5.1 4.7e-05 24.3 5.1 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Rep_fac-A_C PF08646.10 EGG06229.1 - 2.6e-48 163.5 0.2 2.1e-46 157.3 0.1 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EGG06229.1 - 8.8e-34 115.3 0.2 1.9e-33 114.3 0.2 1.6 1 0 0 1 1 1 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 EGG06229.1 - 1.1e-11 44.6 0.6 1.5e-09 37.7 0.1 2.5 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 EGG06229.1 - 1.5e-10 41.0 0.9 6.2e-10 39.0 0.9 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain CDC24_OB3 PF17244.2 EGG06229.1 - 0.0001 22.1 0.0 0.55 9.9 0.0 2.6 2 1 0 2 2 2 2 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 EGG06229.1 - 0.00043 20.5 0.0 0.00097 19.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF223 Peptidase_M16_M PF16187.5 EGG06229.1 - 0.012 14.9 0.1 3.1 7.0 0.0 2.7 3 0 0 3 3 3 0 Middle or third domain of peptidase_M16 DUF4539 PF15072.6 EGG06229.1 - 0.032 14.2 0.0 0.098 12.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) SNARE_assoc PF09335.11 EGG06231.1 - 2.9e-17 63.3 8.8 3.2e-17 63.1 5.5 2.3 3 0 0 3 3 3 1 SNARE associated Golgi protein KCT2 PF17818.1 EGG06231.1 - 0.36 10.9 0.0 0.36 10.9 0.0 1.9 2 1 0 3 3 3 0 Keratinocyte-associated gene product COX2_TM PF02790.15 EGG06231.1 - 0.75 10.0 7.9 0.8 9.9 4.1 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF5305 PF17231.2 EGG06231.1 - 1.1 8.6 2.5 1.9 7.8 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF4149 PF13664.6 EGG06231.1 - 6.1 7.2 8.6 3.6 8.0 1.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) DsbB PF02600.16 EGG06233.1 - 0.061 13.7 1.6 0.1 13.0 1.6 1.4 1 1 0 1 1 1 0 Disulfide bond formation protein DsbB AvrL567-A PF11529.8 EGG06233.1 - 0.15 12.3 0.4 16 5.7 0.0 2.7 1 1 2 3 3 3 0 Melampsora lini avirulence protein AvrL567-A zf-LITAF-like PF10601.9 EGG06233.1 - 0.23 11.7 3.2 9.3 6.6 0.0 3.1 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain Oleosin PF01277.17 EGG06233.1 - 1 9.1 4.6 4.5 7.1 0.3 2.7 1 1 2 3 3 3 0 Oleosin CxC1 PF18802.1 EGG06234.1 - 4.1e-29 100.8 0.2 9e-29 99.7 0.2 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGG06234.1 - 1e-12 48.2 0.6 1.8e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EGG06234.1 - 5.1e-08 33.0 0.1 1.1e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF2789 PF10982.8 EGG06234.1 - 0.027 14.6 0.3 0.06 13.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) UbiA PF01040.18 EGG06236.1 - 7.7e-17 61.4 1.1 8.2e-17 61.3 1.1 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family WD40 PF00400.32 EGG06238.1 - 3.8e-05 24.4 5.4 0.049 14.5 0.7 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat zinc_ribbon_16 PF17034.5 EGG06238.1 - 0.0045 17.2 0.5 0.013 15.7 0.5 1.8 1 0 0 1 1 1 1 Zinc-ribbon like family Questin_oxidase PF14027.6 EGG06241.1 - 2.3e-98 329.9 0.5 2.7e-98 329.6 0.5 1.1 1 0 0 1 1 1 1 Questin oxidase-like DUF1910 PF08928.10 EGG06241.1 - 0.024 14.6 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) DNA_pol_B PF00136.21 EGG06244.1 - 1.1e-118 396.9 0.0 1.5e-118 396.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EGG06244.1 - 7.7e-63 211.6 1.4 1.2e-62 210.9 1.4 1.3 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EGG06244.1 - 2.2e-29 102.7 0.0 9.1e-29 100.6 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain Pkinase PF00069.25 EGG06245.1 - 2.1e-26 92.9 0.0 3.5e-20 72.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG06245.1 - 2.6e-10 40.0 0.0 4.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG06245.1 - 0.014 14.2 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGG06245.1 - 0.054 13.4 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG06245.1 - 0.1 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Inhibitor_I71 PF12628.7 EGG06246.1 - 0.021 14.7 0.9 0.039 13.8 0.9 1.3 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor NAM-associated PF14303.6 EGG06247.1 - 0.51 11.1 6.4 1.2 9.8 6.4 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Macoilin PF09726.9 EGG06247.1 - 0.6 8.6 7.8 0.64 8.5 7.8 1.2 1 0 0 1 1 1 0 Macoilin family Utp12 PF04003.12 EGG06248.1 - 8e-23 80.8 5.3 8e-23 80.8 5.3 1.5 2 0 0 2 2 2 1 Dip2/Utp12 Family UTP15_C PF09384.10 EGG06248.1 - 0.012 15.3 1.5 0.013 15.1 0.2 1.7 2 0 0 2 2 2 0 UTP15 C terminal DUF2563 PF10817.8 EGG06249.1 - 0.038 14.6 0.0 0.058 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2563) Rit1_C PF17184.4 EGG06250.1 - 0.022 14.2 0.1 0.047 13.1 0.1 1.5 1 0 0 1 1 1 0 Rit1 N-terminal domain SAS4 PF15460.6 EGG06251.1 - 0.026 14.6 0.6 0.16 12.1 0.1 2.1 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 Peptidase_C54 PF03416.19 EGG06252.1 - 0.0054 16.2 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 AID PF18767.1 EGG06252.1 - 0.0092 16.0 0.0 0.02 14.9 0.0 1.5 1 1 0 1 1 1 1 Activation induced deaminase D123 PF07065.14 EGG06254.1 - 4.2e-22 78.7 0.1 1.7e-21 76.7 0.1 1.8 1 1 0 1 1 1 1 D123 DUF3195 PF11424.8 EGG06255.1 - 0.1 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGG06255.1 - 0.15 11.0 0.4 0.18 10.7 0.4 1.1 1 0 0 1 1 1 0 NUC194 domain DUF2170 PF09938.9 EGG06255.1 - 0.21 11.3 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) ABC2_membrane PF01061.24 EGG06263.1 - 2.9e-21 75.9 18.1 2.9e-21 75.9 18.1 2.7 2 1 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 EGG06263.1 - 2e-14 53.3 0.0 3.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 CDR ABC transporter GP4 PF03010.14 EGG06263.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 GP4 F-box PF00646.33 EGG06265.1 - 0.011 15.6 0.4 0.031 14.2 0.4 1.8 1 0 0 1 1 1 0 F-box domain CorA PF01544.18 EGG06265.1 - 0.019 14.3 0.1 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FUSC-like PF12805.7 EGG06265.1 - 0.13 11.3 0.2 0.21 10.7 0.2 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS CxC1 PF18802.1 EGG06268.1 - 1.6e-16 60.3 0.0 3.7e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Herpes_LMP1 PF05297.11 EGG06269.1 - 0.19 10.9 1.8 0.24 10.5 1.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) FCH PF00611.23 EGG06272.1 - 3.8e-15 55.9 0.5 9.2e-15 54.7 0.5 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EGG06272.1 - 5.6e-10 38.7 0.1 1.1e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG06272.1 - 1.3e-07 31.2 0.0 2.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGG06272.1 - 3.5e-07 30.0 0.0 6.5e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Adhesin_P1_N PF18652.1 EGG06272.1 - 0.68 10.0 3.0 9.1 6.4 1.2 2.5 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain BUD22 PF09073.10 EGG06273.1 - 0.2 11.0 7.2 0.25 10.6 7.2 1.1 1 0 0 1 1 1 0 BUD22 SCF PF02404.15 EGG06275.1 - 0.0031 16.9 0.2 0.0031 16.9 0.2 1.9 2 0 0 2 2 2 1 Stem cell factor Stevor PF17410.2 EGG06275.1 - 0.023 14.2 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF5305 PF17231.2 EGG06275.1 - 0.029 13.8 0.7 0.063 12.7 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4381 PF14316.6 EGG06275.1 - 0.072 13.3 0.0 0.46 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) stn_TNFRSF12A PF12191.8 EGG06275.1 - 0.16 12.2 0.0 0.99 9.6 0.0 2.3 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SKG6 PF08693.10 EGG06275.1 - 1.1 8.7 3.0 4 6.9 3.0 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M28 PF04389.17 EGG06276.1 - 5.2e-23 81.8 0.0 8.7e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGG06276.1 - 2.8e-06 27.2 0.0 2e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 CttA_N PF18244.1 EGG06276.1 - 0.014 15.8 0.1 0.031 14.7 0.1 1.5 1 0 0 1 1 1 0 Cellulose-binding protein CttA N-terminal domain CxC1 PF18802.1 EGG06277.1 - 0.00077 19.6 0.1 0.0014 18.7 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Cwf_Cwc_15 PF04889.12 EGG06283.1 - 2 8.1 18.1 2.6 7.7 18.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Arg_repressor PF01316.21 EGG06284.1 - 0.00057 19.6 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain HTH_Tnp_Tc3_2 PF01498.18 EGG06284.1 - 0.054 13.7 0.2 0.13 12.5 0.1 1.7 2 0 0 2 2 2 0 Transposase HTH_32 PF13565.6 EGG06284.1 - 0.092 13.4 0.0 0.23 12.1 0.0 1.7 1 1 1 2 2 2 0 Homeodomain-like domain HTH_33 PF13592.6 EGG06284.1 - 0.098 12.3 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix Mersacidin PF16934.5 EGG06286.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) Zn_Tnp_IS1595 PF12760.7 EGG06286.1 - 0.18 11.8 4.6 0.6 10.1 4.6 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.10 EGG06286.1 - 2.1 8.2 10.0 0.94 9.3 0.3 2.7 3 0 0 3 3 3 0 A2L zinc ribbon domain SNARE_assoc PF09335.11 EGG06287.1 - 8.9e-18 64.9 6.8 7.8e-17 61.9 4.4 2.5 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF5305 PF17231.2 EGG06287.1 - 0.082 12.3 0.7 0.43 10.0 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF3671 PF12420.8 EGG06287.1 - 0.86 9.7 11.6 4.1 7.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function EMP24_GP25L PF01105.24 EGG06287.1 - 2.9 7.8 4.4 5.2 7.0 0.3 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD TraL PF07178.11 EGG06287.1 - 7.2 7.2 7.8 5.1 7.6 0.1 3.1 3 0 0 3 3 3 0 TraL protein Metallophos PF00149.28 EGG06288.1 - 1.4e-13 51.8 0.0 3.1e-13 50.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 EGG06288.1 - 0.0021 16.5 0.1 0.01 14.1 0.0 1.9 2 0 0 2 2 2 1 Firmicute fructose-1,6-bisphosphatase NSP2-B_epitope PF14757.6 EGG06288.1 - 0.011 15.4 0.4 0.017 14.8 0.4 1.2 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein DUF3844 PF12955.7 EGG06291.1 - 1.9e-28 98.7 5.5 2.6e-28 98.2 5.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) UCH PF00443.29 EGG06293.1 - 8.8e-74 248.2 0.0 2e-73 247.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGG06293.1 - 1.1e-17 64.5 0.1 3.9e-17 62.6 0.1 2.0 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 EGG06293.1 - 6.1e-14 52.3 7.8 2.6e-07 30.5 0.0 3.9 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-FPG_IleRS PF06827.14 EGG06293.1 - 0.047 13.6 1.5 2 8.4 0.1 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS ubiquitin PF00240.23 EGG06293.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family Peptidase_C98 PF15499.6 EGG06293.1 - 0.1 12.0 0.6 0.87 9.0 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf_UBZ PF18439.1 EGG06293.1 - 0.31 10.7 1.3 4.7 6.9 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger MFS_1 PF07690.16 EGG06299.1 - 0.0012 17.9 5.2 0.0014 17.6 5.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1634 PF07843.11 EGG06300.1 - 0.024 14.7 0.2 0.036 14.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) TraY PF05509.11 EGG06301.1 - 0.15 12.1 0.7 46 4.1 0.1 3.2 3 0 0 3 3 3 0 TraY domain DcuA_DcuB PF03605.14 EGG06302.1 - 0.00085 18.3 0.1 0.0024 16.8 0.0 1.5 1 1 0 2 2 2 1 Anaerobic c4-dicarboxylate membrane transporter DUF1634 PF07843.11 EGG06302.1 - 0.042 13.9 0.2 0.12 12.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) ecTbetaR2 PF08917.10 EGG06303.1 - 0.013 15.4 0.4 0.029 14.3 0.4 1.6 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain Glyco_hydro_38N PF01074.22 EGG06304.1 - 0.04 13.3 0.1 0.06 12.7 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain DUF5598 PF18127.1 EGG06305.1 - 0.047 14.1 0.1 0.27 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5598) PspC PF04024.12 EGG06306.1 - 0.093 12.6 0.2 0.25 11.2 0.2 1.7 1 0 0 1 1 1 0 PspC domain Tim17 PF02466.19 EGG06307.1 - 5e-27 94.5 9.1 1.3e-26 93.2 9.1 1.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family adh_short PF00106.25 EGG06309.1 - 5.2e-34 117.4 0.0 7.2e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG06309.1 - 2.4e-23 82.9 0.0 3.7e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG06309.1 - 5.6e-10 39.4 0.0 9.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.27 EGG06309.1 - 0.011 16.2 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EGG06309.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EGG06309.1 - 0.028 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_Gly3P_dh_N PF01210.23 EGG06309.1 - 0.049 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.6 EGG06309.1 - 0.058 13.3 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding FAD_binding_3 PF01494.19 EGG06309.1 - 0.06 12.6 0.1 0.097 11.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 EGG06309.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EGG06309.1 - 0.11 13.1 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Gag_p10 PF02337.17 EGG06309.1 - 0.18 11.7 0.0 0.86 9.6 0.0 2.0 2 0 0 2 2 2 0 Retroviral GAG p10 protein LRIF1 PF15741.5 EGG06310.1 - 0.028 13.0 2.4 0.028 13.0 2.4 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 RNA_pol_Rpc4 PF05132.14 EGG06310.1 - 0.18 12.2 4.2 0.22 11.9 4.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 TFIIF_alpha PF05793.12 EGG06310.1 - 0.21 10.1 15.1 0.26 9.9 15.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YqfQ PF14181.6 EGG06310.1 - 0.38 11.0 6.3 0.48 10.6 6.3 1.2 1 0 0 1 1 1 0 YqfQ-like protein AP3D1 PF06375.11 EGG06310.1 - 0.61 10.3 13.1 0.84 9.9 13.1 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 CDC45 PF02724.14 EGG06310.1 - 1.4 7.1 6.8 1.4 7.1 6.8 1.0 1 0 0 1 1 1 0 CDC45-like protein FAR1 PF03101.15 EGG06311.1 - 0.049 14.3 0.3 0.22 12.2 0.3 2.1 1 1 0 1 1 1 0 FAR1 DNA-binding domain Ribosomal_L37e PF01907.19 EGG06313.1 - 1.3e-26 92.5 15.5 2.1e-26 91.8 15.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EGG06313.1 - 0.027 14.5 2.1 0.043 13.8 2.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon SelR PF01641.18 EGG06313.1 - 0.038 14.1 1.7 0.044 13.9 1.7 1.3 1 1 0 1 1 1 0 SelR domain HypA PF01155.19 EGG06313.1 - 0.072 13.1 1.2 0.099 12.7 1.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF35_N PF12172.8 EGG06313.1 - 0.32 10.9 5.3 0.65 9.9 5.3 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-C3HC4_2 PF13923.6 EGG06313.1 - 1.1 9.1 4.8 1.9 8.4 4.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF983 PF06170.12 EGG06313.1 - 4.1 7.9 4.1 7.2 7.1 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF983) An_peroxidase PF03098.15 EGG06315.1 - 1.4e-23 83.3 0.0 4.6e-11 42.0 0.1 4.0 2 1 0 2 2 2 2 Animal haem peroxidase SKA2 PF16740.5 EGG06315.1 - 0.16 11.8 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 AAA_33 PF13671.6 EGG06316.1 - 3.6e-11 43.4 0.4 3.2e-05 24.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.6 EGG06316.1 - 0.00073 19.8 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.11 EGG06316.1 - 0.034 14.3 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 tRNA ligase kinase domain ABC_tran PF00005.27 EGG06316.1 - 0.034 14.6 0.0 0.049 14.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EGG06316.1 - 0.035 13.4 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 EGG06316.1 - 0.055 12.5 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 EGG06316.1 - 0.066 13.8 0.1 0.11 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGG06316.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 EGG06316.1 - 0.13 12.3 0.3 0.2 11.7 0.3 1.4 1 1 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 EGG06316.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGG06316.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase HECT PF00632.25 EGG06319.1 - 3.5e-74 250.1 0.0 1.5e-73 248.0 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 EGG06319.1 - 2.8e-05 24.0 0.6 0.23 11.5 0.0 4.1 2 1 1 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGG06319.1 - 0.0067 16.8 1.1 0.049 14.0 0.0 3.2 3 0 0 3 3 3 1 HEAT repeats Adaptin_N PF01602.20 EGG06319.1 - 0.053 12.1 1.2 0.16 10.5 0.1 2.1 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.6 EGG06319.1 - 0.073 13.6 1.2 0.85 10.2 0.1 3.1 2 0 0 2 2 2 0 HEAT-like repeat Methyltransf_12 PF08242.12 EGG06320.1 - 9.4e-14 52.0 0.0 3.7e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG06320.1 - 1.5e-13 51.3 0.0 2.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG06320.1 - 3.3e-09 37.3 0.0 5.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG06320.1 - 6.6e-09 35.8 0.0 9.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG06320.1 - 3.2e-08 33.5 0.0 4.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EGG06320.1 - 2.3e-06 27.0 0.0 0.047 12.9 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_24 PF13578.6 EGG06320.1 - 0.0078 17.2 0.0 0.027 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG06320.1 - 0.0099 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EGG06320.1 - 0.023 14.5 0.0 0.33 10.8 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase DUF3419 PF11899.8 EGG06320.1 - 0.043 13.0 0.0 0.091 11.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3419) MTS PF05175.14 EGG06320.1 - 0.066 12.8 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain She9_MDM33 PF05546.11 EGG06321.1 - 1.9e-62 210.6 5.9 1.9e-62 210.6 5.9 1.6 1 1 0 1 1 1 1 She9 / Mdm33 family Put_Phosphatase PF06888.12 EGG06321.1 - 0.056 12.8 1.4 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Putative Phosphatase DUF1040 PF06288.13 EGG06321.1 - 0.31 11.5 4.6 0.15 12.5 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) DUF3196 PF11428.8 EGG06321.1 - 0.45 10.0 9.9 0.056 13.0 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3196) Pheromone PF08015.11 EGG06321.1 - 5.9 8.0 9.8 1.5 9.9 0.5 2.9 1 1 1 2 2 2 0 Fungal mating-type pheromone IZUMO PF15005.6 EGG06321.1 - 8.1 7.0 9.8 8.5 6.9 3.8 2.5 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Radical_SAM PF04055.21 EGG06322.1 - 9.4e-22 78.2 0.0 3e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.12 EGG06322.1 - 1.4e-21 76.6 0.0 2.7e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 EGG06322.1 - 6.4e-12 45.9 0.0 1.2e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin cNMP_binding PF00027.29 EGG06323.1 - 7.4e-28 96.5 0.0 6.3e-13 48.6 0.0 5.5 4 1 1 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.22 EGG06323.1 - 6e-18 65.8 4.9 3.5e-11 43.7 3.7 2.9 2 0 0 2 2 2 2 Patatin-like phospholipase DUF4661 PF15576.6 EGG06324.1 - 4.8 7.0 7.5 11 5.8 7.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Cys_Met_Meta_PP PF01053.20 EGG06326.1 - 2.1e-30 105.5 0.0 3.3e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGG06326.1 - 0.00014 21.2 0.0 0.00034 19.9 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II An_peroxidase PF03098.15 EGG06327.1 - 3.1e-24 85.5 0.2 2.3e-10 39.7 1.4 5.0 3 1 1 4 4 4 4 Animal haem peroxidase HEAT_EZ PF13513.6 EGG06329.1 - 7.5e-26 90.2 7.0 1e-09 38.6 0.0 9.5 10 0 0 10 10 10 5 HEAT-like repeat HEAT_2 PF13646.6 EGG06329.1 - 1.9e-18 66.6 1.1 7.7e-06 26.2 0.0 7.9 6 2 2 8 8 8 5 HEAT repeats HEAT PF02985.22 EGG06329.1 - 2.1e-18 64.8 12.2 0.00093 19.3 0.1 11.4 12 0 0 12 12 11 4 HEAT repeat UME PF08064.13 EGG06329.1 - 7e-09 35.5 0.4 0.19 11.7 0.0 7.0 5 1 2 7 7 7 3 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 EGG06329.1 - 9.3e-09 35.8 0.0 0.012 16.2 0.0 5.4 7 0 0 7 7 7 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 EGG06329.1 - 6.3e-08 32.4 0.3 3.5e-07 30.0 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cnd1 PF12717.7 EGG06329.1 - 3.6e-07 30.4 0.0 0.031 14.3 0.0 5.4 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EGG06329.1 - 1.1e-05 24.7 0.1 0.16 11.1 0.0 5.2 5 1 1 6 6 6 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 EGG06329.1 - 0.00015 20.5 0.7 0.024 13.2 0.0 3.7 3 2 2 5 5 5 2 Adaptin N terminal region Arm PF00514.23 EGG06329.1 - 0.00032 20.6 8.5 4.7 7.4 0.1 6.2 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EGG06329.1 - 0.00048 19.8 0.0 0.21 11.1 0.0 4.2 4 0 0 4 4 4 1 CLASP N terminal NfI_DNAbd_pre-N PF10524.9 EGG06329.1 - 0.019 14.8 2.9 6.8 6.7 0.0 3.7 4 0 0 4 4 4 0 Nuclear factor I protein pre-N-terminus DUF4639 PF15479.6 EGG06330.1 - 0.49 9.3 5.5 0.93 8.4 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) ArgJ PF01960.18 EGG06331.1 - 1.8e-131 438.3 0.3 2.3e-131 438.0 0.3 1.0 1 0 0 1 1 1 1 ArgJ family UPF0086 PF01868.16 EGG06333.1 - 5.4e-08 32.7 0.2 2.1e-06 27.6 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function UPF0086 Paf1 PF03985.13 EGG06334.1 - 3.2e-56 191.2 0.0 6.8e-56 190.1 0.0 1.5 1 1 0 1 1 1 1 Paf1 CRCB PF02537.15 EGG06335.1 - 3.9e-32 110.4 12.5 3.3e-18 65.8 1.9 2.2 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DUF5325 PF17259.2 EGG06335.1 - 0.29 11.0 0.1 0.29 11.0 0.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5325) Sec3_C PF09763.9 EGG06336.1 - 3.8e-146 488.4 2.9 5.5e-146 487.8 2.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 EGG06336.1 - 1.3e-19 70.1 0.0 2.8e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 EGG06336.1 - 7e-07 28.4 0.5 2e-06 26.8 0.5 1.7 2 0 0 2 2 2 1 Vps52 / Sac2 family DUF16 PF01519.16 EGG06336.1 - 3.3 8.2 7.1 2.8 8.5 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function DUF16 OPT PF03169.15 EGG06337.1 - 1.1e-113 381.0 32.5 3.4e-111 372.8 32.5 2.5 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_M48_N PF16491.5 EGG06337.1 - 0.33 10.8 8.6 0.29 11.0 0.7 2.9 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices VHS PF00790.19 EGG06341.1 - 8.6e-33 113.2 1.1 1.2e-32 112.7 0.1 1.7 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 EGG06341.1 - 8.4e-16 57.3 0.4 2.1e-15 56.0 0.4 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGG06341.1 - 2.9e-14 52.6 1.4 4.1e-14 52.2 0.3 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EGG06341.1 - 6.9e-14 51.3 1.3 2.9e-13 49.3 0.1 2.6 3 1 0 3 3 3 1 Variant SH3 domain GAT PF03127.14 EGG06341.1 - 1.3e-11 44.6 5.7 3.1e-11 43.4 5.7 1.7 1 0 0 1 1 1 1 GAT domain Hrs_helical PF12210.8 EGG06341.1 - 0.021 15.3 2.4 0.054 14.0 2.4 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Dynactin_p22 PF07426.11 EGG06341.1 - 0.094 12.6 4.0 0.18 11.7 4.0 1.4 1 0 0 1 1 1 0 Dynactin subunit p22 DUF445 PF04286.12 EGG06341.1 - 0.5 10.1 2.2 1.3 8.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF445) UIM PF02809.20 EGG06341.1 - 1.6 8.8 5.3 4.1 7.5 5.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif NAD_binding_6 PF08030.12 EGG06344.1 - 1.5e-33 116.2 0.0 2.8e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGG06344.1 - 2.3e-22 79.2 0.0 5.3e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EGG06344.1 - 2.7e-15 56.6 12.0 2.7e-15 56.6 12.0 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component AvrM-A PF18241.1 EGG06347.1 - 0.00059 20.3 6.1 0.0009 19.7 6.1 1.3 1 0 0 1 1 1 1 Flax-rust effector AvrM-A AvrM_N PF18247.1 EGG06347.1 - 0.032 14.2 0.1 0.088 12.8 0.1 1.8 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain RPN6_C_helix PF18503.1 EGG06347.1 - 0.16 11.7 0.2 0.16 11.7 0.2 1.7 2 0 0 2 2 2 0 26S proteasome subunit RPN6 C-terminal helix domain HD_assoc PF13286.6 EGG06348.1 - 0.14 12.7 0.3 0.49 11.0 0.0 2.1 2 0 0 2 2 2 0 Phosphohydrolase-associated domain AvrM_N PF18247.1 EGG06349.1 - 0.0064 16.4 0.6 0.017 15.1 0.1 1.9 2 0 0 2 2 2 1 Flax-rust effector AvrM N-terminal domain GrpE PF01025.19 EGG06349.1 - 0.12 12.0 2.8 1.5 8.5 2.8 2.4 1 1 0 1 1 1 0 GrpE AvrM_N PF18247.1 EGG06350.1 - 0.0034 17.3 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 Flax-rust effector AvrM N-terminal domain ING PF12998.7 EGG06350.1 - 0.061 13.9 0.4 0.13 12.9 0.4 1.5 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding AvrM-A PF18241.1 EGG06350.1 - 0.16 12.4 5.7 0.54 10.7 5.7 1.8 1 1 0 1 1 1 0 Flax-rust effector AvrM-A OmpH PF03938.14 EGG06350.1 - 0.23 11.8 4.9 3.4 8.0 1.7 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FliJ PF02050.16 EGG06350.1 - 0.28 11.4 3.0 0.49 10.6 0.4 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein AvrM_N PF18247.1 EGG06351.1 - 0.071 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain AvrM_N PF18247.1 EGG06352.1 - 0.026 14.5 0.1 0.075 13.0 0.1 1.8 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain EcoR124_C PF12008.8 EGG06352.1 - 0.077 12.6 4.7 0.098 12.3 4.7 1.1 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal AvrM-A PF18241.1 EGG06352.1 - 0.12 12.8 7.6 0.39 11.1 7.6 1.7 1 1 0 1 1 1 0 Flax-rust effector AvrM-A DUF4398 PF14346.6 EGG06354.1 - 2.2 9.0 8.3 4 8.1 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) MBR1 PF17058.5 EGG06355.1 - 0.012 16.0 2.0 0.54 10.5 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial biogenesis regulation protein 1 CRAL_TRIO PF00650.20 EGG06356.1 - 1.8e-32 112.3 0.1 3e-32 111.5 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGG06356.1 - 1.9e-07 31.3 0.0 3.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGG06356.1 - 1.1e-06 28.7 0.0 2.5e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Nop14 PF04147.12 EGG06357.1 - 6.6 4.8 13.8 7.3 4.7 13.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3944 PF13099.6 EGG06362.1 - 0.12 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) CTP_synth_N PF06418.14 EGG06363.1 - 1.2e-120 401.8 0.0 1.5e-120 401.4 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EGG06363.1 - 6.1e-50 169.6 0.0 9.1e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CbiA PF01656.23 EGG06363.1 - 0.013 15.5 0.0 0.014 15.5 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DJ-1_PfpI PF01965.24 EGG06363.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_C26 PF07722.13 EGG06363.1 - 0.075 12.8 0.4 0.35 10.6 0.2 2.2 1 1 1 2 2 2 0 Peptidase C26 ArsA_ATPase PF02374.15 EGG06363.1 - 0.17 11.0 0.1 0.24 10.5 0.1 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase DUF5064 PF16703.5 EGG06364.1 - 0.097 13.2 0.1 13 6.4 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5064) zf-RING_2 PF13639.6 EGG06364.1 - 2.5 8.5 15.2 14 6.1 15.2 2.4 1 1 0 1 1 1 0 Ring finger domain LrgB PF04172.16 EGG06365.1 - 6.1e-32 110.9 10.0 6.1e-32 110.9 10.0 1.7 2 0 0 2 2 2 1 LrgB-like family ABC_membrane_3 PF13748.6 EGG06365.1 - 0.17 11.1 2.2 0.16 11.2 0.3 1.9 2 0 0 2 2 2 0 ABC transporter transmembrane region RRM_1 PF00076.22 EGG06367.1 - 1.4e-21 76.1 0.0 8.4e-17 60.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 EGG06367.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain bZIP_1 PF00170.21 EGG06370.1 - 1.3e-08 34.8 7.2 1.3e-08 34.8 7.2 3.1 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 EGG06370.1 - 3.1e-07 30.3 7.4 3.1e-07 30.3 7.4 3.3 3 0 0 3 3 3 2 Basic region leucine zipper bZIP_Maf PF03131.17 EGG06370.1 - 0.003 18.0 1.7 0.003 18.0 1.7 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor Filament PF00038.21 EGG06370.1 - 0.062 12.9 2.2 0.48 10.0 0.0 2.2 2 0 0 2 2 2 0 Intermediate filament protein TSC22 PF01166.18 EGG06370.1 - 0.067 13.5 0.6 18 5.7 0.0 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF599 PF04654.12 EGG06371.1 - 0.054 12.9 5.2 2.6 7.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF599 GCR1_C PF12550.8 EGG06371.1 - 1.7 9.0 5.9 5.3 7.4 0.8 3.3 2 2 0 2 2 2 0 Transcriptional activator of glycolytic enzymes CLP1_P PF16575.5 EGG06374.1 - 6.8e-34 117.3 0.0 2.1e-22 79.9 0.0 2.4 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 EGG06374.1 - 0.00025 21.1 0.0 0.00047 20.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EGG06374.1 - 0.00068 20.1 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EGG06374.1 - 0.0016 18.5 0.0 0.0057 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGG06374.1 - 0.0025 18.1 0.0 0.0051 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EGG06374.1 - 0.0044 16.1 0.0 0.0068 15.4 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 EGG06374.1 - 0.0094 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EGG06374.1 - 0.011 16.3 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 EGG06374.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EGG06374.1 - 0.032 14.6 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EGG06374.1 - 0.053 13.2 0.0 0.74 9.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EGG06374.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EGG06374.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EGG06374.1 - 0.085 12.8 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 EGG06374.1 - 0.091 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.14 EGG06374.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EGG06374.1 - 0.19 11.4 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ARS2 PF04959.13 EGG06376.1 - 7e-14 52.6 0.1 7e-14 52.6 0.1 4.1 5 0 0 5 5 5 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 EGG06376.1 - 7.1e-14 51.9 1.9 1.6e-13 50.8 1.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) RRM_1 PF00076.22 EGG06376.1 - 0.00012 21.8 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.6 EGG06376.1 - 0.03 14.1 7.6 0.08 12.7 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) DUF1059 PF06348.11 EGG06376.1 - 0.044 14.0 0.4 2.1 8.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) zf-C2H2_2 PF12756.7 EGG06376.1 - 0.8 10.1 4.5 0.75 10.2 0.5 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Kinesin PF00225.23 EGG06377.1 - 7.4e-111 370.3 1.0 1.2e-110 369.6 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 EGG06377.1 - 1.7e-43 148.9 0.6 1.4e-32 113.3 1.3 3.7 2 1 1 3 3 3 2 Kinesin-associated DUF3694 PF12473.8 EGG06377.1 - 5e-32 111.7 0.0 1.8e-31 109.9 0.0 2.1 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 EGG06377.1 - 1.8e-22 79.9 0.0 7.6e-22 77.8 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding PH PF00169.29 EGG06377.1 - 1.8e-12 47.7 0.1 5.7e-12 46.1 0.1 1.9 1 0 0 1 1 1 1 PH domain FHA PF00498.26 EGG06377.1 - 6.2e-08 32.9 0.5 1e-06 29.0 0.1 3.2 4 0 0 4 4 4 1 FHA domain KIF1B PF12423.8 EGG06377.1 - 3.5e-07 30.6 0.1 1e-06 29.0 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein 1B Yop-YscD_cpl PF16697.5 EGG06377.1 - 0.00067 19.9 0.0 0.0029 17.9 0.0 2.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PH_9 PF15410.6 EGG06377.1 - 0.0036 17.7 0.4 0.023 15.1 0.4 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain E1-E2_ATPase PF00122.20 EGG06378.1 - 3.3e-40 137.5 1.8 3.3e-40 137.5 1.8 3.1 2 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGG06378.1 - 5.4e-39 133.8 5.1 5.4e-39 133.8 5.1 3.1 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGG06378.1 - 3.8e-21 76.4 1.9 4.7e-09 36.8 1.2 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG06378.1 - 4.2e-15 55.6 0.1 8.2e-15 54.7 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGG06378.1 - 4.8e-11 42.2 0.1 1.5e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG06378.1 - 2.3e-05 24.3 0.4 8.3e-05 22.4 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG06378.1 - 0.06 13.7 0.0 5.1 7.5 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4149 PF13664.6 EGG06378.1 - 0.11 12.8 0.1 0.11 12.8 0.1 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4149) HCR PF07111.12 EGG06379.1 - 0.013 13.6 1.2 0.014 13.5 1.2 1.0 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) Glyco_hydro_16 PF00722.21 EGG06382.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 Pox_Ag35 PF03286.14 EGG06382.1 - 8.8 6.1 7.4 27 4.5 7.4 1.8 1 1 0 1 1 1 0 Pox virus Ag35 surface protein LRR_4 PF12799.7 EGG06383.1 - 0.00026 21.3 6.4 0.2 12.1 0.3 4.0 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGG06383.1 - 0.0089 15.9 0.0 0.027 14.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like dCMP_cyt_deam_1 PF00383.23 EGG06385.1 - 1.9e-20 72.6 0.0 2.4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGG06385.1 - 6.9e-16 58.2 0.0 1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EGG06385.1 - 0.00036 20.6 1.1 0.067 13.3 1.1 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 EGG06385.1 - 0.0032 17.6 0.0 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 EGG06385.1 - 0.0066 16.5 0.0 0.0092 16.1 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 APOBEC_N PF08210.11 EGG06385.1 - 0.024 14.6 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD1 PF18778.1 EGG06385.1 - 0.037 14.1 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 NAD2 PF18782.1 EGG06385.1 - 0.041 14.0 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 EGG06385.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 TAF4 PF05236.14 EGG06386.1 - 2.9e-10 40.3 0.1 5e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAF4 PF05236.14 EGG06387.1 - 1.9e-05 24.6 20.1 0.001 18.9 20.1 2.7 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Longin PF13774.6 EGG06389.1 - 1e-25 89.6 0.1 1.6e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EGG06389.1 - 9.3e-14 51.0 0.1 1.7e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 EGG06389.1 - 0.034 14.1 0.3 3.5 7.6 0.1 2.1 1 1 1 2 2 2 0 Protein SLM4 OSK PF17182.4 EGG06390.1 - 0.0043 16.3 0.1 0.0066 15.7 0.1 1.2 1 0 0 1 1 1 1 OSK domain Maf1 PF09174.10 EGG06391.1 - 1.3e-36 126.4 6.7 8.4e-29 100.9 0.4 2.7 2 1 1 3 3 3 2 Maf1 regulator Myb_DNA-binding PF00249.31 EGG06392.1 - 7.8e-19 67.6 2.1 1.4e-12 47.6 1.5 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG06392.1 - 2.4e-12 46.9 0.2 1.4e-10 41.3 0.1 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EGG06392.1 - 0.0017 18.4 0.0 0.57 10.2 0.0 2.1 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 EGG06392.1 - 0.03 14.7 0.6 0.67 10.4 0.4 2.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EGG06392.1 - 0.12 12.7 0.1 0.42 11.0 0.0 1.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DFRP_C PF16543.5 EGG06393.1 - 9.9e-22 77.3 2.2 9.9e-22 77.3 2.2 3.0 4 0 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 EGG06393.1 - 6.8e-07 30.0 4.9 0.00012 22.7 1.5 3.1 3 0 0 3 3 3 2 Torus domain zf-CCCH PF00642.24 EGG06393.1 - 3e-06 27.0 1.4 3e-06 27.0 1.4 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGG06393.1 - 3.8e-05 23.4 8.8 0.00017 21.3 2.2 3.1 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGG06393.1 - 0.00011 22.1 15.4 0.00013 21.9 7.6 3.1 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_3 PF15663.5 EGG06393.1 - 0.47 10.7 3.0 1.8 8.8 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGG06393.1 - 2.8 8.5 12.9 0.99 10.0 5.0 2.9 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Peptidase_M24 PF00557.24 EGG06394.1 - 5.6e-53 179.7 0.0 7.5e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGG06394.1 - 1.7e-15 56.8 0.0 4e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 EGG06394.1 - 0.024 14.7 0.5 0.11 12.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3793) AA_permease PF00324.21 EGG06395.1 - 1.7e-114 383.1 36.7 2e-114 382.8 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGG06395.1 - 2.3e-29 102.5 40.5 2.7e-29 102.3 40.5 1.0 1 0 0 1 1 1 1 Amino acid permease Rav1p_C PF12234.8 EGG06396.1 - 6.8e-70 236.2 0.0 1.1e-51 176.1 0.0 2.1 1 1 1 2 2 2 2 RAVE protein 1 C terminal AA_permease PF00324.21 EGG06397.1 - 3e-108 362.5 34.4 3.6e-108 362.2 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGG06397.1 - 1.1e-23 83.8 39.1 1.3e-23 83.5 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease Inhibitor_I78 PF11720.8 EGG06397.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I78 family MBOAT_2 PF13813.6 EGG06401.1 - 1.7e-08 34.6 5.4 6.7e-08 32.7 1.0 2.9 3 0 0 3 3 3 2 Membrane bound O-acyl transferase family EPSP_synthase PF00275.20 EGG06402.1 - 4e-113 378.2 0.0 6.5e-113 377.6 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EGG06402.1 - 2e-102 341.8 0.0 4.2e-102 340.8 0.0 1.6 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EGG06402.1 - 4e-57 194.1 0.0 7e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EGG06402.1 - 6.2e-28 97.9 0.0 2.6e-27 95.9 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EGG06402.1 - 7.7e-24 83.8 0.0 1.9e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 EGG06402.1 - 6.2e-10 39.3 0.0 1.8e-08 34.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 EGG06402.1 - 4.5e-09 35.9 0.0 1.1e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 EGG06402.1 - 9.5e-07 28.8 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 EGG06402.1 - 0.00047 19.1 0.2 0.0046 15.8 0.1 2.3 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase Sacchrp_dh_NADP PF03435.18 EGG06402.1 - 0.024 14.9 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AAA_33 PF13671.6 EGG06402.1 - 0.098 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain JAB PF01398.21 EGG06403.1 - 7.3e-32 109.8 1.1 9.3e-32 109.5 0.1 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EGG06403.1 - 5.1e-20 72.2 0.5 1.3e-19 70.9 0.5 1.7 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EGG06403.1 - 0.00026 20.7 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EGG06403.1 - 0.028 14.5 0.1 0.068 13.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) GFD1 PF17331.2 EGG06403.1 - 0.22 11.8 1.1 0.39 11.0 1.1 1.4 1 0 0 1 1 1 0 GFD1 mRNA transport factor Sugar_tr PF00083.24 EGG06406.1 - 9.6e-92 308.2 16.9 1.1e-91 308.0 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG06406.1 - 6.6e-18 64.7 40.9 5.3e-16 58.5 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sporozoite_P67 PF05642.11 EGG06408.1 - 0.23 9.5 1.3 0.27 9.3 1.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cytochrom_B561 PF03188.16 EGG06411.1 - 4.1e-10 39.9 9.8 4.1e-10 39.9 9.8 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 EGG06411.1 - 8.9e-10 38.5 0.0 3.5e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 EGG06411.1 - 0.015 15.1 6.3 0.034 13.9 5.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) DOMON PF03351.17 EGG06411.1 - 0.057 13.6 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 DOMON domain DUF1129 PF06570.11 EGG06411.1 - 0.15 11.5 3.9 0.31 10.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4267 PF14087.6 EGG06411.1 - 0.55 10.3 2.7 0.5 10.4 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) Pkinase PF00069.25 EGG06412.1 - 1.8e-16 60.3 0.0 2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG06412.1 - 1e-09 38.0 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG06412.1 - 0.0086 16.0 0.3 0.036 14.0 0.4 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG06412.1 - 0.011 14.7 0.2 0.015 14.3 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EGG06412.1 - 0.093 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 RIO1 family WSD PF15613.6 EGG06415.1 - 0.22 12.0 1.2 2.1 8.9 0.0 2.8 2 1 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif MIF4G_like PF09088.11 EGG06417.1 - 8.9e-58 195.2 0.0 2.5e-57 193.8 0.0 1.8 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EGG06417.1 - 1.3e-42 146.2 21.9 2.4e-42 145.2 14.5 3.0 2 1 0 2 2 2 1 MIF4G like HNF-1_N PF04814.13 EGG06417.1 - 0.0055 17.4 5.8 0.0055 17.4 5.8 2.3 2 0 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF1319 PF07028.11 EGG06417.1 - 0.21 11.8 4.7 0.59 10.4 4.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) ArAE_2_N PF10337.9 EGG06417.1 - 6.8 5.6 7.3 4.4 6.2 0.0 2.7 3 0 0 3 3 3 0 Putative ER transporter, 6TM, N-terminal Borrelia_P83 PF05262.11 EGG06420.1 - 4.4 5.7 16.1 5.2 5.4 16.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein HSP70 PF00012.20 EGG06421.1 - 1.6e-255 849.0 12.3 1.8e-255 848.8 12.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGG06421.1 - 9e-18 64.2 0.6 5.5e-16 58.3 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 EGG06421.1 - 0.0017 17.4 0.3 0.21 10.5 0.2 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 EGG06421.1 - 0.058 12.7 1.5 0.078 12.2 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Sad1_UNC PF07738.13 EGG06424.1 - 2.2e-28 98.9 0.0 3e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal PBP_like PF12727.7 EGG06424.1 - 0.18 10.9 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 PBP superfamily domain FGGY_C PF02782.16 EGG06425.1 - 2.6e-44 151.3 0.0 3.6e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGG06425.1 - 5.6e-23 81.8 0.0 1.9e-22 80.0 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EGG06425.1 - 1.7e-05 24.5 0.1 0.0053 16.3 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 EGG06425.1 - 0.03 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 ROK family Hexokinase_1 PF00349.21 EGG06425.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Hexokinase Thioredoxin PF00085.20 EGG06426.1 - 2.5e-45 152.7 0.2 8.8e-21 73.8 0.1 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EGG06426.1 - 2.1e-12 47.3 0.0 1.7e-08 34.6 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EGG06426.1 - 0.00087 19.7 0.4 0.045 14.2 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGG06426.1 - 0.0045 17.3 0.0 2.7 8.4 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 EGG06426.1 - 0.029 14.3 0.3 0.79 9.6 0.0 2.7 2 1 0 2 2 2 0 AhpC/TSA family Thioredoxin_9 PF14595.6 EGG06426.1 - 0.047 13.5 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.6 EGG06426.1 - 0.14 12.3 0.3 0.96 9.7 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like Glutaredoxin PF00462.24 EGG06426.1 - 1.8 8.9 4.2 0.55 10.5 0.1 2.3 2 1 0 2 2 2 0 Glutaredoxin TPR_2 PF07719.17 EGG06427.1 - 1.1e-19 68.9 21.3 0.058 13.5 0.0 12.3 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGG06427.1 - 1.7e-17 62.4 12.3 0.0068 16.2 0.0 10.4 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGG06427.1 - 2.7e-13 50.2 28.7 0.00075 20.0 0.1 9.7 7 4 4 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.6 EGG06427.1 - 2.9e-12 46.7 16.8 0.011 16.0 0.0 8.9 9 1 2 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGG06427.1 - 4.2e-11 42.1 10.2 0.11 12.7 0.0 9.0 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG06427.1 - 6.3e-10 39.5 23.3 0.14 12.9 0.0 9.6 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGG06427.1 - 2.8e-07 30.2 9.7 0.98 9.4 0.1 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG06427.1 - 1.4e-06 27.9 10.9 0.11 12.6 0.0 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG06427.1 - 8e-06 26.2 27.6 0.067 13.9 0.0 11.9 12 1 0 12 12 10 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG06427.1 - 1e-05 25.9 38.0 0.79 10.7 0.0 11.7 9 4 5 14 14 12 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGG06427.1 - 1.4e-05 24.7 11.4 0.037 13.7 0.1 6.4 6 0 0 6 6 6 2 TPR repeat ANAPC3 PF12895.7 EGG06427.1 - 5.9e-05 23.2 11.5 2.2 8.6 0.1 5.5 5 0 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EGG06427.1 - 0.0028 18.1 2.1 0.53 11.1 0.2 5.0 6 0 0 6 6 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG06427.1 - 0.0037 17.6 12.6 35 5.1 0.0 9.2 11 1 1 12 12 11 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGG06427.1 - 0.0071 16.5 1.2 2 8.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPPII_N PF12583.8 EGG06427.1 - 0.072 13.7 0.8 13 6.4 0.0 3.8 3 0 0 3 3 2 0 Tripeptidyl peptidase II N terminal PH PF00169.29 EGG06428.1 - 2.9e-06 27.7 0.0 0.00064 20.2 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 EGG06428.1 - 4.8e-05 23.7 0.0 9.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4325 PF14213.6 EGG06429.1 - 0.09 12.5 0.1 6.2 6.6 0.0 2.8 2 0 0 2 2 2 0 STAS-like domain of unknown function (DUF4325) LRR_4 PF12799.7 EGG06429.1 - 0.14 12.6 12.1 1.7 9.2 0.7 4.9 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG06429.1 - 0.45 10.3 4.3 55 3.6 4.0 3.6 2 1 0 2 2 2 0 Leucine rich repeat Glyco_hydro_18 PF00704.28 EGG06430.1 - 1e-50 173.3 5.0 1.3e-50 172.9 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_S9_N PF02897.15 EGG06431.1 - 2.9e-95 319.5 0.1 4.3e-95 319.0 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EGG06431.1 - 7.7e-62 208.5 0.0 1.3e-61 207.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EGG06431.1 - 0.045 12.4 0.0 0.077 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EGG06431.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AJAP1_PANP_C PF15298.6 EGG06431.1 - 2.5 8.3 8.6 4.4 7.5 8.6 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus GDI PF00996.18 EGG06433.1 - 7.3e-16 57.7 0.1 2.9e-15 55.8 0.1 2.1 1 1 0 1 1 1 1 GDP dissociation inhibitor TIP49 PF06068.13 EGG06434.1 - 5.5e-161 535.6 0.1 1.3e-160 534.4 0.1 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGG06434.1 - 5.6e-20 71.2 0.1 1.3e-19 70.0 0.1 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EGG06434.1 - 5.9e-11 42.9 0.1 1.6e-06 28.5 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGG06434.1 - 4e-09 36.4 0.0 3e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGG06434.1 - 4.6e-06 27.0 0.1 0.12 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGG06434.1 - 7.1e-05 23.3 0.0 0.0008 19.8 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EGG06434.1 - 0.00016 21.9 0.1 0.0019 18.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGG06434.1 - 0.00046 20.6 0.7 0.15 12.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGG06434.1 - 0.0012 18.8 0.1 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGG06434.1 - 0.0066 16.2 0.2 5.7 6.6 0.0 2.7 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_25 PF13481.6 EGG06434.1 - 0.0066 16.0 0.0 0.023 14.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGG06434.1 - 0.0099 15.3 0.1 0.24 10.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 EGG06434.1 - 0.016 14.6 0.0 0.041 13.2 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 EGG06434.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EGG06434.1 - 0.02 14.2 0.1 0.052 12.8 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 EGG06434.1 - 0.021 14.1 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EGG06434.1 - 0.065 12.6 0.1 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.6 EGG06434.1 - 0.077 12.7 0.2 2.8 7.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGG06434.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTF2 PF02136.20 EGG06435.1 - 0.00064 20.3 0.2 0.00087 19.9 0.2 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain HdeA PF06411.11 EGG06436.1 - 0.007 16.5 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 HdeA/HdeB family Malic_M PF03949.15 EGG06436.1 - 0.02 14.2 0.1 0.028 13.7 0.1 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Peptidase_C3G PF12381.8 EGG06436.1 - 0.21 11.0 1.1 0.3 10.5 0.1 1.6 2 0 0 2 2 2 0 Tungro spherical virus-type peptidase IMPDH PF00478.25 EGG06437.1 - 2.3e-134 447.8 1.0 2.6e-134 447.6 1.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGG06437.1 - 1.7e-08 33.9 1.2 3.4e-08 32.9 1.2 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase CBS PF00571.28 EGG06437.1 - 2.3e-08 34.4 0.0 0.0018 18.7 0.0 2.8 2 0 0 2 2 2 2 CBS domain His_biosynth PF00977.21 EGG06437.1 - 8.9e-06 25.3 3.1 2.9e-05 23.7 0.9 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 EGG06437.1 - 9.7e-06 25.2 8.8 0.00017 21.1 6.9 2.7 2 1 1 3 3 3 1 Nitronate monooxygenase ThiG PF05690.14 EGG06437.1 - 0.0034 16.7 1.6 0.0073 15.6 1.6 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 EGG06437.1 - 0.012 14.8 1.6 0.073 12.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Dus PF01207.17 EGG06437.1 - 0.037 13.1 0.3 0.56 9.2 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 EGG06437.1 - 0.14 11.5 0.2 2.5 7.5 0.1 2.5 3 0 0 3 3 3 0 Glycerol-3-phosphate responsive antiterminator YpsA PF06908.11 EGG06437.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family GDA1_CD39 PF01150.17 EGG06438.1 - 6.1e-104 348.0 0.0 8.1e-104 347.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 EGG06438.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family AAA_31 PF13614.6 EGG06438.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-CCHC PF00098.23 EGG06440.1 - 0.22 11.7 2.5 0.33 11.1 2.5 1.3 1 0 0 1 1 1 0 Zinc knuckle Glyco_hydro_16 PF00722.21 EGG06441.1 - 7.9e-08 32.0 0.0 1.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1223 PF06764.11 EGG06442.1 - 0.044 13.8 0.2 0.064 13.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1223) O-FucT PF10250.9 EGG06443.1 - 9.8e-06 25.5 0.1 0.00049 19.9 0.0 2.8 2 1 1 3 3 3 1 GDP-fucose protein O-fucosyltransferase Ferlin_C PF16165.5 EGG06443.1 - 0.058 13.3 0.7 0.11 12.5 0.7 1.4 1 0 0 1 1 1 0 Ferlin C-terminus DUF4293 PF14126.6 EGG06443.1 - 0.38 11.0 4.1 0.32 11.2 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) CxC1 PF18802.1 EGG06445.1 - 0.058 13.5 0.1 0.093 12.9 0.1 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases DUF4675 PF15720.5 EGG06452.1 - 0.016 15.0 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4675) Metallophos PF00149.28 EGG06453.1 - 7.1e-36 124.6 0.8 1e-35 124.1 0.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGG06453.1 - 0.00011 22.5 0.2 0.00022 21.6 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 EGG06453.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Peptidase_M24 PF00557.24 EGG06457.1 - 2.9e-23 82.7 0.0 3.9e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Chorismate_synt PF01264.21 EGG06459.1 - 3.2e-138 459.9 0.1 3.7e-138 459.7 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase NDUF_B8 PF05821.11 EGG06461.1 - 1e-07 32.0 0.1 3.6e-07 30.2 0.1 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DPBB_1 PF03330.18 EGG06464.1 - 0.0033 17.7 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase PRMT5 PF05185.16 EGG06465.1 - 6e-60 202.0 0.0 8.8e-60 201.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EGG06465.1 - 4.6e-50 169.9 0.1 7.5e-50 169.2 0.1 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 EGG06465.1 - 2.4e-45 154.7 0.1 3.8e-45 154.1 0.1 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain NMDAR2_C PF10565.9 EGG06465.1 - 0.19 10.5 0.3 0.28 10.0 0.3 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Met_10 PF02475.16 EGG06465.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Cpn60_TCP1 PF00118.24 EGG06466.1 - 3.9e-140 467.7 13.0 4.5e-140 467.5 13.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EGG06466.1 - 0.071 12.6 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Mannosidase_ig PF17786.1 EGG06466.1 - 0.076 13.6 0.1 0.23 12.1 0.1 1.8 1 0 0 1 1 1 0 Mannosidase Ig/CBM-like domain DUF3336 PF11815.8 EGG06467.1 - 1.2e-48 164.3 2.0 2.1e-48 163.5 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EGG06467.1 - 1.4e-17 64.5 0.1 3.3e-17 63.4 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase YycI PF09648.10 EGG06468.1 - 0.056 13.0 0.5 0.095 12.3 0.5 1.3 1 0 0 1 1 1 0 YycH protein PALP PF00291.25 EGG06469.1 - 2.4e-67 227.4 0.0 3e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pyr_redox_2 PF07992.14 EGG06470.1 - 2.8e-51 174.5 0.2 4.8e-51 173.7 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG06470.1 - 4e-10 40.1 0.0 2.7e-09 37.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG06470.1 - 0.096 11.9 0.0 3.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UbiA PF01040.18 EGG06471.1 - 4.5e-29 101.5 10.5 4.5e-29 101.5 10.5 2.0 1 1 1 2 2 2 1 UbiA prenyltransferase family SET PF00856.28 EGG06472.1 - 5.1e-13 49.8 0.0 1e-12 48.8 0.0 1.5 1 0 0 1 1 1 1 SET domain tRNA_int_end_N2 PF12928.7 EGG06474.1 - 7.1e-16 58.2 0.0 1.6e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EGG06474.1 - 0.0062 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain DUF423 PF04241.15 EGG06475.1 - 0.076 13.2 0.7 0.24 11.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Sec66 PF09802.9 EGG06475.1 - 0.13 11.8 0.2 0.21 11.1 0.2 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 MFS_1 PF07690.16 EGG06476.1 - 1.2e-18 67.2 63.1 1.3e-14 53.9 38.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PDT PF00800.18 EGG06478.1 - 1.1e-36 126.4 0.0 1.6e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase Csc2 PF18320.1 EGG06478.1 - 0.023 13.7 0.1 0.031 13.2 0.1 1.1 1 0 0 1 1 1 0 Csc2 Crispr GlyL_C PF12524.8 EGG06479.1 - 0.029 14.5 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 dsDNA virus glycoprotein L C terminal Ras PF00071.22 EGG06480.1 - 0.089 12.4 0.0 0.097 12.3 0.0 1.1 1 0 0 1 1 1 0 Ras family DUF3500 PF12006.8 EGG06481.1 - 0.05 13.1 1.1 0.13 11.8 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3500) LTXXQ PF07813.12 EGG06481.1 - 0.29 11.9 4.2 1.5 9.6 0.1 3.2 2 2 0 2 2 2 0 LTXXQ motif family protein Actin PF00022.19 EGG06482.1 - 7.7e-85 285.0 0.0 1.1e-83 281.2 0.0 1.9 1 1 0 1 1 1 1 Actin FtsA PF14450.6 EGG06482.1 - 0.0098 16.3 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Cell division protein FtsA Yae1_N PF09811.9 EGG06484.1 - 2e-12 46.6 3.4 3.1e-12 46.0 3.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RNA_pol_3_Rpc31 PF11705.8 EGG06485.1 - 4.8e-13 49.9 22.7 2.2e-12 47.7 22.7 1.9 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 HAND PF09110.11 EGG06485.1 - 0.033 15.0 4.8 0.05 14.4 4.8 1.3 1 0 0 1 1 1 0 HAND HMG_box PF00505.19 EGG06493.1 - 3.3e-15 56.2 3.3 7.5e-15 55.1 3.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGG06493.1 - 9.6e-09 35.7 3.6 2.6e-08 34.4 3.6 1.8 1 0 0 1 1 1 1 HMG-box domain NOA36 PF06524.12 EGG06493.1 - 0.045 13.1 20.2 1.9 7.8 0.1 2.3 2 0 0 2 2 2 0 NOA36 protein AT_hook PF02178.19 EGG06493.1 - 0.13 12.2 3.9 0.59 10.2 3.9 2.2 1 0 0 1 1 1 0 AT hook motif SDA1 PF05285.12 EGG06493.1 - 4.1 6.7 26.5 1 8.7 14.4 2.3 2 0 0 2 2 2 0 SDA1 Sugar_tr PF00083.24 EGG06494.1 - 1.1e-90 304.7 25.0 1.3e-90 304.4 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG06494.1 - 1.7e-15 56.9 41.6 9.6e-15 54.3 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP_synth_reg PF14960.6 EGG06494.1 - 0.14 11.6 0.1 0.63 9.6 0.1 2.1 1 0 0 1 1 1 0 ATP synthase regulation Dscam_C PF12355.8 EGG06495.1 - 0.44 11.5 9.8 0.58 11.1 9.4 1.7 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal DUF5542 PF17696.1 EGG06496.1 - 2 8.6 3.8 1.6 8.9 1.9 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5542) XPG_I PF00867.18 EGG06497.1 - 2.6e-29 101.4 0.0 5.4e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EGG06497.1 - 9.5e-26 90.2 0.0 2.1e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EGG06497.1 - 9.9e-05 21.9 0.0 0.0002 20.9 0.0 1.5 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 EGG06497.1 - 0.03 14.9 0.0 0.11 13.1 0.0 1.9 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold WD40 PF00400.32 EGG06499.1 - 5.3e-10 39.7 12.4 0.036 15.0 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG06499.1 - 0.00011 22.5 0.0 0.2 12.0 0.0 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGG06499.1 - 0.11 11.0 0.1 2.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF4786 PF16027.5 EGG06501.1 - 2.8 8.5 18.1 0.26 11.9 2.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4786) GRAB PF10375.9 EGG06502.1 - 0.0039 17.0 1.2 0.0039 17.0 1.2 1.9 2 0 0 2 2 2 1 GRIP-related Arf-binding domain SNF2_N PF00176.23 EGG06503.1 - 1.4e-48 165.4 4.3 1.1e-27 96.7 0.5 2.0 1 1 1 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 EGG06503.1 - 0.00024 21.2 0.1 0.1 12.6 0.0 2.1 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGG06503.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DEAD PF00270.29 EGG06503.1 - 0.076 12.8 0.1 6 6.6 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.6 EGG06503.1 - 0.11 12.8 0.3 0.29 11.4 0.2 1.8 2 1 0 2 2 2 0 AAA domain Nramp PF01566.18 EGG06505.1 - 3.2e-40 138.2 9.1 5.7e-28 97.9 4.5 3.0 2 1 1 3 3 3 3 Natural resistance-associated macrophage protein Glyco_hydro_12 PF01670.16 EGG06506.1 - 3.5e-19 69.6 1.6 4.7e-19 69.2 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Nramp PF01566.18 EGG06507.1 - 4.6e-73 246.3 16.0 1.2e-36 126.5 5.8 2.3 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Jiraiya PF15038.6 EGG06507.1 - 0.013 14.9 1.6 0.14 11.6 0.0 3.1 3 0 0 3 3 3 0 Jiraiya ASFV_J13L PF05568.11 EGG06507.1 - 0.074 12.8 0.6 2.8 7.7 0.3 2.7 2 0 0 2 2 2 0 African swine fever virus J13L protein SseC PF04888.12 EGG06507.1 - 1.2 8.6 6.0 0.18 11.3 0.2 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family SNF2_N PF00176.23 EGG06508.1 - 2.5e-57 194.2 0.0 6e-56 189.7 0.0 2.5 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG06508.1 - 1.4e-16 60.9 0.0 4.6e-15 55.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG06508.1 - 9.5e-11 42.0 0.0 2.8e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG06508.1 - 1.9e-07 31.0 0.0 4.7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 EGG06508.1 - 9e-07 28.7 12.0 9e-07 28.7 12.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG06508.1 - 1.1e-06 28.4 10.8 1.1e-06 28.4 10.8 2.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG06508.1 - 2.3e-06 27.4 11.6 2.3e-06 27.4 11.6 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG06508.1 - 5.3e-06 26.7 13.6 5.3e-06 26.7 13.6 2.7 2 1 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 EGG06508.1 - 2.3e-05 24.1 10.7 2.3e-05 24.1 10.7 2.0 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGG06508.1 - 0.00051 19.9 12.7 0.00051 19.9 12.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain DEAD_2 PF06733.15 EGG06508.1 - 0.01 15.5 0.5 0.14 11.8 0.1 2.6 2 1 0 2 2 2 0 DEAD_2 zf-rbx1 PF12678.7 EGG06508.1 - 0.011 16.0 8.5 0.032 14.5 8.5 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain AAA_34 PF13872.6 EGG06508.1 - 0.016 14.1 0.1 0.035 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-RING_6 PF14835.6 EGG06508.1 - 0.025 14.4 4.7 0.055 13.3 4.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EGG06508.1 - 0.03 14.4 3.2 0.073 13.1 3.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 EGG06508.1 - 2.6 7.9 8.4 5.5 6.9 8.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS91 PF14319.6 EGG06508.1 - 5.7 7.0 14.9 2.8 8.0 3.0 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-P11 PF03854.14 EGG06508.1 - 8.1 6.2 17.6 0.066 12.9 7.3 2.3 2 0 0 2 2 2 0 P-11 zinc finger LRR_4 PF12799.7 EGG06510.1 - 1.8e-06 28.2 2.7 6.1e-06 26.5 2.7 1.9 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG06510.1 - 1e-05 25.2 1.1 2.6e-05 23.9 1.1 1.6 1 0 0 1 1 1 1 Leucine rich repeat CENP-B_dimeris PF09026.10 EGG06510.1 - 0.0084 16.5 13.0 0.018 15.4 13.0 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain LRR_1 PF00560.33 EGG06510.1 - 0.014 15.9 3.8 2.8 8.8 0.3 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat eIF-3c_N PF05470.12 EGG06510.1 - 0.038 12.3 3.8 0.56 8.4 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus LRR_6 PF13516.6 EGG06510.1 - 0.12 12.5 1.2 5.9 7.2 0.1 3.0 2 0 0 2 2 2 0 Leucine Rich repeat PI3K_1B_p101 PF10486.9 EGG06510.1 - 0.16 9.7 3.2 0.28 8.9 3.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop14 PF04147.12 EGG06510.1 - 0.18 10.0 5.3 0.25 9.5 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 EGG06510.1 - 0.45 10.2 3.3 1 9.0 3.3 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 EGG06510.1 - 0.49 8.6 4.0 0.68 8.1 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 EGG06510.1 - 1.1 7.2 5.9 1.7 6.6 5.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.12 EGG06510.1 - 1.2 8.4 5.7 1.9 7.8 5.7 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EGG06510.1 - 1.3 7.0 13.7 2.1 6.3 13.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 EGG06510.1 - 6.4 5.8 16.5 11 5.0 16.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 EGG06510.1 - 6.5 6.0 16.9 13 5.0 16.9 1.4 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EGG06510.1 - 7.3 6.6 6.7 13 5.8 6.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal BUD22 PF09073.10 EGG06510.1 - 8.9 5.5 8.7 13 5.0 8.7 1.2 1 0 0 1 1 1 0 BUD22 Velvet PF11754.8 EGG06512.1 - 6.6e-16 59.0 0.4 3.2e-14 53.5 0.0 2.0 1 1 1 2 2 2 2 Velvet factor Mito_carr PF00153.27 EGG06515.1 - 4.5e-65 215.6 3.7 1.2e-20 73.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA_int_endo PF01974.17 EGG06516.1 - 4e-14 52.5 0.0 7.4e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EGG06516.1 - 0.016 14.9 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain Lipase_3 PF01764.25 EGG06517.1 - 1.3e-12 47.8 0.0 1.9e-11 44.0 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 EGG06517.1 - 0.18 11.3 0.6 0.35 10.3 0.1 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) WW PF00397.26 EGG06518.1 - 2.4e-11 43.5 2.8 5.8e-11 42.3 2.8 1.7 1 0 0 1 1 1 1 WW domain WW PF00397.26 EGG06519.1 - 2.9e-07 30.4 4.1 5.7e-07 29.5 4.1 1.5 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 EGG06519.1 - 0.00034 20.8 18.1 0.00034 20.8 18.1 2.3 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) PUF PF00806.19 EGG06523.1 - 0.15 11.8 0.3 1.1 9.1 0.0 2.5 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat SAPS PF04499.15 EGG06525.1 - 1.3 7.7 11.7 1.4 7.7 11.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 EGG06525.1 - 2 7.4 11.2 2.2 7.2 11.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 EGG06525.1 - 2.4 6.2 17.3 2.7 6.0 17.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Podoplanin PF05808.11 EGG06525.1 - 3.9 7.6 16.0 4.7 7.3 16.0 1.1 1 0 0 1 1 1 0 Podoplanin Apt1 PF10351.9 EGG06525.1 - 5.3 5.8 25.2 7.9 5.2 25.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain EVI2A PF05399.11 EGG06525.1 - 9.5 5.7 17.8 13 5.3 17.8 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) p450 PF00067.22 EGG06527.1 - 5e-59 200.3 0.0 6.7e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EGG06528.1 - 8.3e-66 222.0 0.3 2.8e-65 220.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG06528.1 - 1.4e-30 106.5 0.1 1.1e-29 103.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.26 EGG06528.1 - 2.7e-11 43.6 1.4 6.6e-11 42.4 0.4 2.2 2 0 0 2 2 2 1 FHA domain Pkinase_fungal PF17667.1 EGG06528.1 - 0.0017 17.2 0.0 0.0046 15.8 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGG06528.1 - 0.023 14.6 0.0 7.4 6.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Zip PF02535.22 EGG06530.1 - 4.8 6.3 4.8 4.7 6.3 4.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DSPc PF00782.20 EGG06531.1 - 1.1e-34 119.1 0.0 1.8e-25 89.3 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG06531.1 - 2.6e-05 23.9 0.0 0.031 13.8 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Myotub-related PF06602.14 EGG06531.1 - 0.001 18.1 0.0 0.16 10.8 0.0 2.2 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain Lon_C PF05362.13 EGG06532.1 - 6.1e-62 208.8 0.0 1.4e-61 207.6 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EGG06532.1 - 3.5e-27 95.6 0.3 9.5e-27 94.2 0.3 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EGG06532.1 - 2.7e-23 82.8 0.0 1.5e-22 80.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGG06532.1 - 1.6e-07 31.4 0.0 4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 EGG06532.1 - 8.5e-06 24.9 0.0 1.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain ChlI PF13541.6 EGG06532.1 - 1.3e-05 25.1 0.1 2.8e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 EGG06532.1 - 4.6e-05 23.6 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGG06532.1 - 0.00021 21.1 0.0 0.0011 18.8 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGG06532.1 - 0.00022 21.5 0.4 0.0069 16.7 0.1 3.1 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGG06532.1 - 0.00022 21.7 0.0 0.0014 19.1 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EGG06532.1 - 0.0021 18.1 0.0 0.0052 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG06532.1 - 0.0053 17.3 0.3 0.035 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGG06532.1 - 0.017 14.9 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGG06532.1 - 0.021 14.6 0.0 0.064 13.0 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein RXT2_N PF08595.11 EGG06532.1 - 0.021 14.8 0.2 0.021 14.8 0.2 5.1 4 1 1 5 5 5 0 RXT2-like, N-terminal RNA_helicase PF00910.22 EGG06532.1 - 0.03 14.7 0.0 0.072 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 EGG06532.1 - 0.049 12.8 0.2 0.88 8.7 0.1 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_3 PF07726.11 EGG06532.1 - 0.063 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EGG06532.1 - 0.069 13.1 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 EGG06532.1 - 0.071 13.6 3.1 0.4 11.2 0.1 3.4 4 0 0 4 4 3 0 ABC transporter SKI PF01202.22 EGG06532.1 - 0.075 13.2 0.0 0.25 11.4 0.0 2.0 1 0 0 1 1 1 0 Shikimate kinase NTPase_1 PF03266.15 EGG06532.1 - 0.14 12.0 1.0 0.94 9.4 0.0 2.7 2 1 1 3 3 2 0 NTPase DSPn PF14671.6 EGG06533.1 - 9.9e-38 129.8 0.0 4.2e-36 124.5 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EGG06533.1 - 5e-16 58.7 0.0 1.1e-15 57.6 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG06533.1 - 0.00015 21.4 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGG06533.1 - 0.0024 18.0 0.0 0.0038 17.3 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGG06533.1 - 0.0083 16.1 0.0 0.011 15.7 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family DUF3280 PF11684.8 EGG06535.1 - 0.33 11.4 2.4 1.5 9.3 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2380) Pkinase PF00069.25 EGG06536.1 - 1e-65 221.8 0.0 1.6e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG06536.1 - 2.4e-34 118.8 0.0 3.1e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG06536.1 - 1.3e-10 41.0 0.0 2.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGG06536.1 - 0.00019 20.4 0.0 0.00031 19.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGG06536.1 - 0.00089 18.7 0.3 0.0019 17.6 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG06536.1 - 0.0024 17.8 0.4 0.0044 17.0 0.4 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG06536.1 - 0.02 13.9 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EGG06536.1 - 0.11 12.2 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 EGG06536.1 - 0.12 11.3 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase WD40 PF00400.32 EGG06539.1 - 1.9e-37 126.6 13.3 1.4e-06 28.9 0.4 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG06539.1 - 2.6e-10 40.4 0.2 0.62 10.4 0.0 5.6 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EGG06539.1 - 3.8e-07 28.8 0.0 7e-07 27.9 0.0 1.4 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 EGG06539.1 - 1.5e-06 27.4 1.4 3.2e-06 26.3 0.0 2.2 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 EGG06539.1 - 3.6e-05 22.7 0.1 0.0017 17.1 0.0 2.9 2 1 2 4 4 4 1 Nup133 N terminal like Nup160 PF11715.8 EGG06539.1 - 0.01 14.5 1.2 0.75 8.4 0.0 3.8 3 1 2 5 5 5 0 Nucleoporin Nup120/160 AMP-binding PF00501.28 EGG06540.1 - 1.2e-82 277.8 0.0 1.6e-82 277.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PmrD PF11183.8 EGG06540.1 - 0.13 12.4 0.0 0.64 10.2 0.0 2.1 2 0 0 2 2 2 0 Polymyxin resistance protein PmrD HGD-D PF06050.13 EGG06542.1 - 0.034 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DnaJ PF00226.31 EGG06543.1 - 1.9e-08 34.3 0.0 1.2e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 EGG06543.1 - 0.002 18.6 0.1 3.3 8.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG06543.1 - 0.002 18.2 1.6 4.3 7.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG06543.1 - 0.036 14.3 0.2 6.5 7.1 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGG06543.1 - 0.038 14.0 0.9 22 5.4 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG06543.1 - 0.039 14.6 6.8 2.2 9.1 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG06543.1 - 0.067 13.5 2.5 4.5 7.6 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG06543.1 - 0.31 11.3 1.2 40 4.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Sad1_UNC PF07738.13 EGG06545.1 - 7.8e-31 106.8 0.0 1.2e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Alpha_kinase PF02816.18 EGG06546.1 - 5e-14 52.8 0.0 5.8e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Cytochrom_C PF00034.21 EGG06549.1 - 3.1e-10 41.1 0.3 4.9e-10 40.4 0.3 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGG06549.1 - 9.7e-07 29.0 4.6 1.1e-05 25.7 4.6 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EGG06549.1 - 0.019 14.7 0.8 0.034 13.9 0.4 1.7 1 1 0 1 1 1 0 Cytochrome c-550 domain UPF0128 PF03673.13 EGG06549.1 - 0.094 12.2 0.1 0.11 12.0 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) IPPT PF01715.17 EGG06550.1 - 2.9e-60 203.9 0.0 4.1e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 IPP transferase AAA_18 PF13238.6 EGG06550.1 - 0.0059 17.1 0.0 0.24 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain GPHH PF16905.5 EGG06550.1 - 0.0088 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated DUF2075 PF09848.9 EGG06550.1 - 0.028 13.6 0.8 0.052 12.8 0.0 1.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EGG06550.1 - 0.041 14.2 0.4 1.8 8.8 0.1 2.9 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 EGG06550.1 - 0.042 14.4 1.2 0.14 12.7 0.2 2.2 2 1 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 EGG06550.1 - 0.17 12.0 1.4 0.77 9.9 0.7 2.5 2 1 0 2 2 2 0 AAA domain PMT_4TMC PF16192.5 EGG06551.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase KilA-N PF04383.13 EGG06552.1 - 0.0036 17.1 0.0 0.0036 17.1 0.0 1.1 1 0 0 1 1 1 1 KilA-N domain Synaptobrevin PF00957.21 EGG06553.1 - 2.2e-14 53.0 0.7 4.1e-14 52.1 0.7 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGG06553.1 - 2.5e-13 49.9 0.0 5.2e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Cu_amine_oxidN3 PF02728.16 EGG06553.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain CxC6 PF18721.1 EGG06555.1 - 6.5e-21 74.4 0.8 1.8e-20 73.0 0.8 1.8 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 EGG06555.1 - 7.7e-16 58.2 2.4 2.1e-15 56.8 2.4 1.7 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases zf-met2 PF12907.7 EGG06557.1 - 9.2e-18 64.1 2.9 9.2e-18 64.1 2.9 1.6 2 0 0 2 2 2 1 Zinc-binding 4F5 PF04419.14 EGG06557.1 - 1.7e-07 32.0 12.1 1.3e-06 29.1 8.6 2.1 2 0 0 2 2 2 1 4F5 protein family DUF1005 PF06219.12 EGG06557.1 - 0.0049 16.0 0.4 0.0051 15.9 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1005) zf-C2H2_4 PF13894.6 EGG06557.1 - 0.083 13.8 0.2 0.15 13.0 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger MFS_1 PF07690.16 EGG06559.1 - 5.7e-42 143.9 48.3 3.6e-40 138.0 46.5 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG06559.1 - 7e-10 38.3 5.5 7e-10 38.3 5.5 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EGG06559.1 - 1.3e-07 30.5 25.9 4.6e-07 28.6 25.9 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.16 EGG06559.1 - 0.33 10.6 6.7 0.068 12.9 2.3 2.0 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 PseudoU_synth_2 PF00849.22 EGG06560.1 - 1.1e-17 64.6 0.1 1.3e-15 57.8 0.1 2.3 1 1 0 1 1 1 1 RNA pseudouridylate synthase DUF2863 PF11062.8 EGG06560.1 - 0.14 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) GFA PF04828.14 EGG06560.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme MmlI PF09448.10 EGG06561.1 - 0.13 12.8 0.0 0.13 12.8 0.0 1.4 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase CxC1 PF18802.1 EGG06563.1 - 0.022 14.9 0.2 0.036 14.2 0.2 1.3 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Phosducin PF02114.16 EGG06563.1 - 0.094 11.6 0.0 0.64 8.9 0.0 1.9 2 0 0 2 2 2 0 Phosducin E1-E2_ATPase PF00122.20 EGG06567.1 - 3e-50 170.3 2.9 5.6e-49 166.1 1.0 2.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGG06567.1 - 8.8e-25 87.5 18.1 6.1e-20 71.7 4.3 3.4 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGG06567.1 - 1.4e-22 81.1 1.7 1.8e-13 51.3 0.0 3.6 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG06567.1 - 3.8e-19 68.6 0.0 8.9e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGG06567.1 - 2.2e-11 43.2 0.2 5.6e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG06567.1 - 1.7e-05 24.7 1.2 0.02 14.7 0.8 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2273 PF10031.9 EGG06567.1 - 6 7.0 9.7 0.2 11.7 0.7 2.9 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) OPA3 PF07047.12 EGG06569.1 - 1.8e-29 102.0 0.1 2.3e-29 101.7 0.1 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) MutS_V PF00488.21 EGG06571.1 - 2.7e-29 102.5 2.8 2.7e-19 69.9 0.4 3.6 2 1 1 3 3 3 2 MutS domain V MutS_III PF05192.18 EGG06571.1 - 5.3e-12 46.3 0.2 1.2e-11 45.2 0.2 1.7 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EGG06571.1 - 0.019 15.3 0.0 0.066 13.6 0.0 1.9 2 0 0 2 2 2 0 MutS family domain IV Rer1 PF03248.13 EGG06572.1 - 7.2e-75 250.4 1.9 8.3e-75 250.2 1.9 1.0 1 0 0 1 1 1 1 Rer1 family DUF4395 PF14340.6 EGG06572.1 - 0.023 15.0 2.1 0.22 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) DUF2208 PF09973.9 EGG06572.1 - 0.048 13.3 1.0 0.048 13.3 1.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Sin3a_C PF16879.5 EGG06573.1 - 2.4e-47 162.0 1.0 2.5e-46 158.7 0.6 2.4 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 EGG06573.1 - 6.1e-40 135.1 6.9 4.1e-16 58.8 0.0 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EGG06573.1 - 2.3e-26 91.7 0.0 3.7e-25 87.8 0.0 2.8 2 0 0 2 2 2 1 Sin3 family co-repressor Foie-gras_1 PF11817.8 EGG06574.1 - 2e-34 119.3 0.5 2.7e-33 115.7 0.1 2.2 2 0 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 EGG06574.1 - 1.6e-10 40.4 2.5 6.9e-06 25.1 0.0 3.3 2 1 1 3 3 3 3 Gryzun, putative trafficking through Golgi SNAP PF14938.6 EGG06574.1 - 0.00066 19.2 0.5 0.0017 17.8 0.5 1.7 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Gryzun-like PF12742.7 EGG06574.1 - 0.021 14.8 0.2 0.055 13.5 0.2 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking TPR_1 PF00515.28 EGG06575.1 - 3.4e-10 39.3 12.5 1.7e-05 24.5 1.5 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG06575.1 - 3.7e-07 29.7 11.7 0.015 15.3 0.5 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGG06575.1 - 5.8e-05 23.3 5.5 0.005 17.1 2.8 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG06575.1 - 0.02 15.5 5.7 3.9 8.2 0.1 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGG06575.1 - 0.097 12.6 4.4 1.3 8.9 0.1 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG06575.1 - 0.41 11.6 3.6 2.1 9.4 1.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG06575.1 - 1.1 9.5 6.1 1.2 9.4 2.2 3.0 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EGG06575.1 - 1.5 9.6 5.2 47 5.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGG06575.1 - 1.8 9.0 15.0 6.2 7.3 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG06575.1 - 4.4 8.2 5.8 38 5.2 1.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4049 PF13258.6 EGG06578.1 - 0.037 13.1 0.2 0.047 12.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) JTB PF05439.12 EGG06579.1 - 0.051 13.6 6.4 0.17 12.0 6.4 1.9 1 1 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) CxC1 PF18802.1 EGG06582.1 - 1.2e-28 99.3 0.2 1.9e-28 98.7 0.2 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG06582.1 - 6.8e-08 32.6 0.1 1e-07 32.0 0.1 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG06582.1 - 0.0013 18.6 0.1 0.0021 17.9 0.1 1.3 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases WEMBL PF05701.11 EGG06585.1 - 0.014 14.1 0.1 0.017 13.9 0.1 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light OTU PF02338.19 EGG06590.1 - 0.0086 16.6 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGG06590.1 - 0.035 13.5 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase C65 Otubain SNARE PF05739.19 EGG06592.1 - 1.3e-12 47.5 0.1 3.8e-12 46.0 0.1 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EGG06592.1 - 0.00027 20.7 10.7 0.00071 19.3 0.1 2.8 3 0 0 3 3 3 1 Syntaxin Syntaxin-5_N PF11416.8 EGG06592.1 - 0.0005 19.2 0.2 0.0005 19.2 0.2 2.7 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin-18_N PF10496.9 EGG06592.1 - 0.0023 18.2 2.1 0.0095 16.2 0.0 2.9 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus DUF16 PF01519.16 EGG06592.1 - 0.0041 17.6 0.8 0.0041 17.6 0.8 2.4 2 0 0 2 2 2 1 Protein of unknown function DUF16 Rx_N PF18052.1 EGG06592.1 - 0.032 14.5 1.7 0.76 10.1 0.0 2.5 2 0 0 2 2 2 0 Rx N-terminal domain zf-C4H2 PF10146.9 EGG06592.1 - 0.25 11.6 8.6 2.5 8.4 0.4 2.5 2 1 0 2 2 2 0 Zinc finger-containing protein SlyX PF04102.12 EGG06592.1 - 0.39 11.3 10.6 0.33 11.6 1.2 2.9 2 1 0 2 2 2 0 SlyX FliJ PF02050.16 EGG06592.1 - 0.66 10.2 12.1 0.07 13.4 2.6 2.8 3 0 0 3 3 3 0 Flagellar FliJ protein DUF5082 PF16888.5 EGG06592.1 - 0.71 10.2 10.7 8.4 6.7 1.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Atg14 PF10186.9 EGG06592.1 - 0.79 8.7 5.8 1.9 7.5 0.1 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ABC_tran_CTD PF16326.5 EGG06592.1 - 1.4 9.2 7.0 11 6.4 0.9 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain Fib_alpha PF08702.10 EGG06592.1 - 5.5 7.2 14.4 4.7 7.4 1.4 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family LPP PF04728.13 EGG06592.1 - 5.9 7.4 10.2 5.5 7.5 1.2 2.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper CDC45 PF02724.14 EGG06594.1 - 0.048 12.0 21.4 0.05 11.9 21.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 EGG06594.1 - 0.13 12.4 23.7 0.17 12.0 23.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Mucin PF01456.17 EGG06594.1 - 0.25 11.3 3.4 0.3 11.1 3.4 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein TFIIF_alpha PF05793.12 EGG06594.1 - 0.5 8.9 32.1 0.56 8.7 32.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RR_TM4-6 PF06459.12 EGG06594.1 - 0.67 9.7 17.3 1 9.1 17.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Merozoite_SPAM PF07133.11 EGG06594.1 - 1.1 9.3 43.1 1.5 8.8 43.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2151 PF10221.9 EGG06594.1 - 1.1 7.8 14.8 1.2 7.6 14.8 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Rtf2 PF04641.12 EGG06594.1 - 2.9 7.2 16.2 3.5 6.9 16.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger SLC12 PF03522.15 EGG06594.1 - 3.8 6.4 15.5 4.4 6.2 15.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Vfa1 PF08432.10 EGG06594.1 - 4.1 7.7 20.4 5.1 7.4 20.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 EGG06594.1 - 4.9 6.5 29.4 6 6.2 29.4 1.1 1 0 0 1 1 1 0 SDA1 FAM76 PF16046.5 EGG06594.1 - 5.2 6.3 13.5 6.2 6.1 13.5 1.0 1 0 0 1 1 1 0 FAM76 protein Nop53 PF07767.11 EGG06594.1 - 6.5 6.0 28.3 7.9 5.8 28.3 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RRN3 PF05327.11 EGG06594.1 - 7 5.1 18.9 8.9 4.7 18.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM60A PF15396.6 EGG06594.1 - 7.3 6.5 11.1 8.7 6.3 11.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PI3K_1B_p101 PF10486.9 EGG06594.1 - 8.4 4.0 14.8 9.2 3.9 14.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Peptidase_S64 PF08192.11 EGG06594.1 - 8.7 4.7 12.9 9.7 4.5 12.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 EGG06594.1 - 9.2 4.9 19.3 11 4.7 19.3 1.1 1 0 0 1 1 1 0 Presenilin zf_CCCH_4 PF18345.1 EGG06595.1 - 1.2e-11 44.3 13.3 2.6e-06 27.3 3.7 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EGG06595.1 - 7.5e-11 41.6 8.9 4.4e-07 29.5 1.7 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 EGG06595.1 - 3.1e-10 39.7 9.2 1.2e-06 28.3 1.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGG06595.1 - 2.6e-07 31.3 3.1 0.014 16.1 0.1 2.8 3 0 0 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 EGG06595.1 - 1.2e-05 25.6 11.7 0.012 16.1 2.7 3.0 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EGG06595.1 - 0.0055 16.9 1.8 0.12 12.6 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger containing family Mem_trans PF03547.18 EGG06597.1 - 5.7e-30 104.0 1.5 3.5e-29 101.4 1.5 2.1 1 1 0 1 1 1 1 Membrane transport protein Clat_adaptor_s PF01217.20 EGG06598.1 - 1.4e-39 135.3 0.1 1.6e-39 135.1 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fungal_trans_2 PF11951.8 EGG06598.1 - 0.089 11.6 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF2340 PF10209.9 EGG06598.1 - 0.11 13.0 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) Peptidase_M41 PF01434.18 EGG06599.1 - 1.4e-62 210.9 0.0 2.2e-62 210.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGG06599.1 - 1.3e-41 142.1 0.0 3.7e-41 140.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG06599.1 - 2.7e-13 49.5 0.1 6e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EGG06599.1 - 3.6e-09 37.0 0.3 3.6e-09 37.0 0.3 2.4 2 0 0 2 2 2 1 FtsH Extracellular RuvB_N PF05496.12 EGG06599.1 - 0.0024 17.6 0.0 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGG06599.1 - 0.003 16.8 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_17 PF13207.6 EGG06599.1 - 0.013 15.9 0.2 0.062 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGG06599.1 - 0.014 15.8 0.1 0.15 12.4 0.2 2.3 1 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EGG06599.1 - 0.021 15.1 0.0 0.73 10.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain TMEM51 PF15345.6 EGG06599.1 - 0.022 14.6 1.3 0.038 13.8 1.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 AAA_5 PF07728.14 EGG06599.1 - 0.027 14.5 0.1 0.098 12.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGG06599.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EGG06599.1 - 0.12 12.5 0.4 0.47 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) Formyl_trans_N PF00551.19 EGG06601.1 - 3.1e-39 134.6 0.0 3.7e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Nuc_N PF14448.6 EGG06601.1 - 0.061 13.2 0.8 5.6 6.9 0.1 3.2 3 0 0 3 3 3 0 Nuclease N terminal LCIB_C_CA PF18599.1 EGG06603.1 - 0.11 11.7 7.3 0.46 9.8 0.5 2.2 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF948 PF06103.11 EGG06603.1 - 0.14 12.4 4.3 0.38 11.0 0.3 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec20 PF03908.13 EGG06603.1 - 0.49 10.3 2.9 2.8 7.9 0.3 2.4 2 0 0 2 2 2 0 Sec20 DUF1754 PF08555.10 EGG06606.1 - 0.09 13.6 0.0 0.16 12.8 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Mem_trans PF03547.18 EGG06607.1 - 1e-26 93.3 0.3 1e-26 93.3 0.3 2.2 2 1 0 2 2 2 1 Membrane transport protein Dec-1 PF04624.14 EGG06607.1 - 4.9 7.1 9.4 0.073 12.9 1.1 2.1 2 0 0 2 2 2 0 Dec-1 repeat DUF1754 PF08555.10 EGG06609.1 - 0.34 11.7 13.1 0.27 12.1 3.2 2.2 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF4407 PF14362.6 EGG06609.1 - 0.89 8.9 9.5 1.2 8.4 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PBP1_TM PF14812.6 EGG06609.1 - 3.7 8.0 10.7 0.56 10.6 4.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Presenilin PF01080.17 EGG06609.1 - 5.2 5.7 8.8 6.5 5.4 8.8 1.1 1 0 0 1 1 1 0 Presenilin zf-C2H2 PF00096.26 EGG06611.1 - 0.042 14.3 1.8 0.042 14.3 1.8 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF3614 PF12267.8 EGG06611.1 - 0.4 11.2 4.2 1.2 9.6 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Mem_trans PF03547.18 EGG06612.1 - 2.6e-27 95.2 8.4 2.6e-27 95.2 8.4 1.5 2 0 0 2 2 2 1 Membrane transport protein Memo PF01875.17 EGG06613.1 - 6.7e-79 264.8 0.0 8.2e-79 264.5 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Nop53 PF07767.11 EGG06613.1 - 0.4 10.0 1.0 0.62 9.4 1.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FMN_dh PF01070.18 EGG06614.1 - 0.07 12.1 0.0 0.071 12.1 0.0 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase HTH_45 PF14947.6 EGG06617.1 - 0.0025 17.7 0.6 7.3 6.7 0.0 3.3 3 0 0 3 3 3 2 Winged helix-turn-helix Pep3_Vps18 PF05131.14 EGG06619.1 - 1.8e-35 121.9 0.0 3.8e-35 120.9 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EGG06619.1 - 5.4e-13 49.0 7.3 3e-09 36.9 0.1 3.4 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 EGG06619.1 - 9.7e-07 29.2 0.5 9.7e-07 29.2 0.5 2.6 3 1 1 4 4 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 EGG06619.1 - 0.00016 21.6 3.8 0.00016 21.6 3.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGG06619.1 - 0.0009 19.3 0.3 1.3 9.1 0.7 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EGG06619.1 - 0.0011 18.8 4.3 0.004 17.0 4.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGG06619.1 - 0.0026 17.4 1.7 0.0064 16.2 1.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGG06619.1 - 0.0067 16.4 1.1 0.016 15.3 1.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3H2C3 PF17122.5 EGG06619.1 - 0.015 15.3 2.2 0.045 13.8 2.2 1.8 1 0 0 1 1 1 0 Zinc-finger zf-rbx1 PF12678.7 EGG06619.1 - 0.015 15.6 1.8 0.33 11.3 3.4 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EGG06619.1 - 0.034 13.8 6.5 0.051 13.2 3.0 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF2175 PF09943.9 EGG06619.1 - 0.043 14.1 5.3 0.057 13.7 1.4 3.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4 PF00097.25 EGG06619.1 - 0.08 12.8 3.3 0.23 11.4 3.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG06619.1 - 0.21 11.9 8.3 0.046 14.1 4.2 2.1 2 0 0 2 2 1 0 Ring finger domain Usp PF00582.26 EGG06622.1 - 2.1e-21 76.9 0.3 4.2e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 Universal stress protein family Asp4 PF16996.5 EGG06622.1 - 0.29 10.9 0.9 3.3 7.6 0.0 2.5 1 1 1 2 2 2 0 Accessory secretory protein Sec Asp4 Mnd1 PF03962.15 EGG06623.1 - 2.6e-25 88.5 0.1 6.2e-25 87.3 0.1 1.7 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 EGG06623.1 - 4.2e-08 33.2 0.6 4.2e-08 33.2 0.6 2.4 2 0 0 2 2 2 1 Leucine zipper with capping helix domain AAA_13 PF13166.6 EGG06623.1 - 0.0018 17.0 3.8 0.0019 16.9 3.8 1.0 1 0 0 1 1 1 1 AAA domain Methyltransf_7 PF03492.15 EGG06623.1 - 0.016 14.5 0.7 0.017 14.3 0.7 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase KCNQ_channel PF03520.14 EGG06623.1 - 0.016 15.1 1.4 0.4 10.5 0.0 2.3 1 1 1 2 2 2 0 KCNQ voltage-gated potassium channel DUF4891 PF16232.5 EGG06623.1 - 0.046 14.2 0.1 0.095 13.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4891) DivIC PF04977.15 EGG06623.1 - 1.4 8.7 9.4 0.99 9.2 0.5 2.3 1 1 1 2 2 2 0 Septum formation initiator OPT PF03169.15 EGG06624.1 - 4.5e-85 286.5 48.6 1.1e-62 212.6 32.3 2.0 2 0 0 2 2 2 2 OPT oligopeptide transporter protein PfkB PF00294.24 EGG06625.1 - 4.6e-36 124.6 0.0 7.4e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Nitro_FeMo-Co PF02579.17 EGG06625.1 - 0.028 14.7 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Ala_racemase_N PF01168.20 EGG06625.1 - 0.046 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain MRP-L28 PF09812.9 EGG06626.1 - 9.7e-07 29.1 8.5 1.7e-06 28.3 6.4 1.9 1 1 1 2 2 2 1 Mitochondrial ribosomal protein L28 Borrelia_lipo_1 PF05714.11 EGG06626.1 - 0.00019 21.3 0.3 0.00022 21.1 0.3 1.1 1 0 0 1 1 1 1 Borrelia burgdorferi virulent strain associated lipoprotein SpoIIIAH PF12685.7 EGG06626.1 - 0.013 15.3 2.1 0.016 15.0 2.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Atg14 PF10186.9 EGG06626.1 - 3 6.9 8.3 4.2 6.4 8.3 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Raptor_N PF14538.6 EGG06627.1 - 3.2e-54 182.9 0.0 6.2e-54 182.0 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EGG06627.1 - 3.9e-05 24.3 7.3 1.4 9.9 0.1 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT PF02985.22 EGG06627.1 - 0.0001 22.2 0.1 0.022 15.0 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat BBS2_Mid PF14783.6 EGG06627.1 - 0.025 14.6 0.3 2.9 8.0 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 EGG06627.1 - 0.031 14.5 0.1 4.5 7.6 0.0 3.4 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Pox_MCEL PF03291.16 EGG06629.1 - 2.8e-77 260.1 0.0 3.2e-77 259.9 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EGG06629.1 - 5.4e-13 49.5 0.0 8.5e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG06629.1 - 2.5e-09 37.1 0.0 3.4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG06629.1 - 3.9e-09 37.2 0.0 6.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG06629.1 - 4.6e-09 36.8 0.0 7.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG06629.1 - 2.2e-07 30.9 0.0 4e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EGG06629.1 - 0.00016 21.0 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.17 EGG06629.1 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 EGG06629.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 EGG06629.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Zn_ribbon_17 PF17120.5 EGG06630.1 - 5.4e-09 35.6 15.6 5.4e-09 35.6 15.6 2.2 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EGG06630.1 - 0.00017 22.3 17.8 0.057 14.3 0.1 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat RWD PF05773.22 EGG06630.1 - 0.017 15.4 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 RWD domain zf-C3HC4_2 PF13923.6 EGG06630.1 - 0.43 10.5 10.3 1.2 9.0 10.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGG06630.1 - 0.51 10.7 13.8 1.8 8.9 13.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Peptidase_C50 PF03568.17 EGG06631.1 - 3.6e-128 428.1 0.0 4.3e-128 427.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 EGG06631.1 - 8.4e-09 35.2 0.0 0.0025 17.3 0.0 2.3 1 1 1 2 2 2 2 CHAT domain HypF_C PF17788.1 EGG06632.1 - 0.043 14.5 0.2 0.061 14.0 0.2 1.3 1 1 0 1 1 1 0 HypF Kae1-like domain Epimerase PF01370.21 EGG06633.1 - 7.8e-16 58.3 0.0 2.3e-15 56.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG06633.1 - 4.8e-14 52.0 0.0 1.3e-13 50.6 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGG06633.1 - 4e-11 42.6 0.1 1.6e-10 40.6 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGG06633.1 - 1.5e-09 37.7 0.0 5.7e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGG06633.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGG06633.1 - 0.044 12.9 0.0 0.18 10.9 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.25 EGG06633.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 EGG06634.1 - 8.9e-16 58.1 0.0 6.3e-15 55.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG06634.1 - 2.4e-12 46.5 0.0 5.9e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGG06634.1 - 7.3e-11 41.7 0.0 4.7e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGG06634.1 - 6.5e-08 32.4 0.4 2.6e-06 27.1 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 EGG06634.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 EGG06634.1 - 0.022 14.7 0.4 0.069 13.1 0.3 2.0 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 EGG06635.1 - 1.4e-12 47.6 0.0 7.3e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG06635.1 - 2.3e-12 46.5 0.0 4.8e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGG06635.1 - 2.6e-07 30.4 0.0 4.6e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGG06635.1 - 6.5e-06 25.5 0.1 0.00011 21.5 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EGG06635.1 - 0.021 14.0 0.0 0.19 10.8 0.0 2.3 2 1 0 2 2 2 0 RmlD substrate binding domain PEX11 PF05648.14 EGG06637.1 - 2e-62 210.6 3.8 2.2e-62 210.4 3.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ORC4_C PF14629.6 EGG06638.1 - 2.2e-27 95.9 0.0 5.5e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EGG06638.1 - 3.9e-10 40.4 0.0 3.7e-08 33.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGG06638.1 - 9e-05 22.8 0.1 0.00024 21.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGG06638.1 - 0.00023 21.6 0.1 0.0015 18.9 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGG06638.1 - 0.002 18.4 0.0 0.0041 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGG06638.1 - 0.0024 17.1 0.2 0.021 14.0 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF815) HU-CCDC81_bac_2 PF18175.1 EGG06638.1 - 0.024 14.5 0.3 0.42 10.5 0.2 2.4 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 RNase_E_G PF10150.9 EGG06638.1 - 0.025 14.0 0.2 0.057 12.8 0.2 1.5 1 0 0 1 1 1 0 Ribonuclease E/G family T2SSE PF00437.20 EGG06638.1 - 0.12 11.4 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 EGG06638.1 - 0.15 11.6 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RVT_3 PF13456.6 EGG06641.1 - 0.04 13.7 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase-like RNase_H PF00075.24 EGG06641.1 - 0.17 12.0 0.0 0.46 10.6 0.0 1.7 2 0 0 2 2 2 0 RNase H zf-RNPHF PF08080.12 EGG06642.1 - 0.075 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 RNPHF zinc finger Alpha_kinase PF02816.18 EGG06643.1 - 4.9e-09 36.6 0.1 7.8e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family RhoGAP PF00620.27 EGG06644.1 - 3.4e-28 98.4 0.0 9.3e-28 97.0 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain Ribonuclease_3 PF00636.26 EGG06646.1 - 7e-08 33.0 0.1 0.0011 19.5 0.0 3.0 2 2 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGG06646.1 - 0.0037 17.4 0.0 1.8 8.7 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease-III-like UQ_con PF00179.26 EGG06647.1 - 3.5e-46 156.3 0.1 4.1e-46 156.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGG06647.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 EGG06647.1 - 0.17 12.2 1.1 0.5 10.7 1.1 2.0 1 1 0 1 1 1 0 RWD domain Sec34 PF04136.15 EGG06649.1 - 2.6e-41 141.0 6.9 7.9e-41 139.4 6.9 1.9 1 0 0 1 1 1 1 Sec34-like family YlbD_coat PF14071.6 EGG06649.1 - 0.03 14.6 1.7 0.11 12.7 1.1 2.2 2 0 0 2 2 2 0 Putative coat protein Mvb12 PF09452.10 EGG06649.1 - 0.4 11.1 4.1 4.6 7.7 1.1 2.9 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 SPG4 PF17325.2 EGG06652.1 - 0.37 11.9 4.9 0.51 11.5 4.0 1.6 1 1 0 1 1 1 0 Stationary phase protein 4 Med9 PF07544.13 EGG06655.1 - 0.052 13.7 0.8 0.12 12.5 0.8 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Alpha-amyl_C2 PF07821.12 EGG06657.1 - 0.14 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain Adap_comp_sub PF00928.21 EGG06659.1 - 5.7e-91 304.5 0.0 9.1e-91 303.9 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGG06659.1 - 2.5e-09 37.2 0.9 4.4e-09 36.4 0.9 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EGG06659.1 - 0.0053 16.2 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Ribosomal_S8 PF00410.19 EGG06661.1 - 1.2e-11 44.6 0.0 1.5e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 DUF2269 PF10027.9 EGG06663.1 - 0.14 12.2 2.8 0.26 11.3 2.8 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Cyclin_N PF00134.23 EGG06664.1 - 2e-44 150.4 0.7 2e-43 147.1 0.5 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGG06664.1 - 1e-27 96.6 0.0 1.9e-26 92.5 0.0 2.6 1 1 0 1 1 1 1 Cyclin, C-terminal domain TMA7 PF09072.10 EGG06664.1 - 8.7 7.3 7.9 13 6.8 7.9 1.2 1 0 0 1 1 1 0 Translation machinery associated TMA7 WD40 PF00400.32 EGG06666.1 - 5.3e-14 52.4 9.5 2.9e-06 27.9 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EGG06666.1 - 6.9e-14 51.9 0.2 5.9e-12 45.7 0.0 3.2 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 EGG06666.1 - 5.1e-05 23.5 0.6 0.06 13.6 0.1 4.0 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 EGG06666.1 - 0.05 12.8 0.1 0.14 11.4 0.0 1.8 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller CxC5 PF18718.1 EGG06667.1 - 1.5e-06 28.3 0.9 1.6e-06 28.2 0.2 1.5 2 0 0 2 2 2 1 CxC5 like cysteine cluster associated with KDZ transposases NTR2 PF15458.6 EGG06668.1 - 0.034 13.7 0.3 0.046 13.3 0.3 1.1 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Retrotran_gag_2 PF14223.6 EGG06671.1 - 1.3e-06 28.1 0.5 1.9e-06 27.6 0.5 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGG06671.1 - 0.03 14.1 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type TcdB_N PF12918.7 EGG06671.1 - 0.079 13.3 0.8 1.1 9.6 0.2 2.5 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain TelA PF05816.11 EGG06672.1 - 0.66 9.0 2.0 0.4 9.7 0.2 1.5 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) F-box_4 PF15966.5 EGG06673.1 - 0.0047 16.8 0.3 0.37 10.7 0.0 2.4 2 0 0 2 2 2 2 F-box F-box-like PF12937.7 EGG06673.1 - 0.15 12.0 5.0 2.1 8.3 5.0 2.5 1 1 0 1 1 1 0 F-box-like F-box PF00646.33 EGG06673.1 - 0.29 11.1 5.7 0.51 10.3 0.3 3.2 2 0 0 2 2 2 0 F-box domain TPR_MalT PF17874.1 EGG06675.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 MalT-like TPR region ST7 PF04184.12 EGG06675.1 - 0.035 12.6 0.3 0.057 11.9 0.3 1.3 1 0 0 1 1 1 0 ST7 protein TPR_2 PF07719.17 EGG06675.1 - 0.063 13.4 0.0 2.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CDC4_D PF16856.5 EGG06675.1 - 0.33 10.8 11.5 0.96 9.4 1.3 2.9 3 0 0 3 3 3 0 Cell division control protein 4 dimerisation domain MBOAT_2 PF13813.6 EGG06676.1 - 2.1e-14 53.6 0.8 5.7e-14 52.2 0.2 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family CxC1 PF18802.1 EGG06677.1 - 1.2e-34 118.6 0.4 2.4e-34 117.6 0.4 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG06677.1 - 3e-05 24.1 0.1 7.5e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG06677.1 - 0.0015 18.4 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases Cupin_8 PF13621.6 EGG06679.1 - 7.5e-44 150.3 0.1 1.1e-43 149.8 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGG06679.1 - 0.008 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein ASRT PF07100.11 EGG06679.1 - 0.054 13.6 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 Anabaena sensory rhodopsin transducer zf-Mss51 PF13824.6 EGG06680.1 - 5e-17 61.7 0.3 9.9e-17 60.8 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 SR-25 PF10500.9 EGG06681.1 - 2.7 7.5 12.5 3.8 7.1 12.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Retrotran_gag_2 PF14223.6 EGG06682.1 - 0.00023 20.8 0.1 0.00029 20.5 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DENN PF02141.21 EGG06683.1 - 3.6e-20 72.7 0.9 6.7e-20 71.8 0.0 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain RHH_1 PF01402.21 EGG06683.1 - 0.19 11.7 0.8 0.84 9.7 0.8 2.1 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family IgG_binding_B PF01378.17 EGG06684.1 - 0.0089 16.1 0.6 3.6 7.7 0.1 2.7 2 0 0 2 2 2 2 B domain Dyp_perox PF04261.12 EGG06685.1 - 2.9e-06 26.5 0.0 0.00048 19.2 0.0 3.3 4 0 0 4 4 4 2 Dyp-type peroxidase family Sin_N PF04801.13 EGG06686.1 - 1.5e-17 64.0 0.0 2.1e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Amidohydro_1 PF01979.20 EGG06688.1 - 1.4e-07 31.1 0.0 1.5e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Dyp_perox PF04261.12 EGG06690.1 - 7.5e-11 41.6 0.0 1.7e-08 33.9 0.0 3.1 2 1 0 2 2 2 2 Dyp-type peroxidase family CDC27 PF09507.10 EGG06691.1 - 3.5 6.9 12.3 5.4 6.3 12.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Dicty_REP PF05086.12 EGG06695.1 - 1.5 6.7 4.2 2.1 6.2 4.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FAM104 PF15434.6 EGG06695.1 - 4.9 7.7 12.4 1.2 9.7 2.3 3.1 2 2 1 3 3 3 0 Family 104 vMSA PF00695.19 EGG06696.1 - 0.064 12.3 0.3 0.078 12.1 0.3 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Tmemb_9 PF05434.11 EGG06697.1 - 4 7.3 7.0 9 6.2 7.0 1.7 1 1 0 1 1 1 0 TMEM9 DnaJ PF00226.31 EGG06698.1 - 3.1e-16 59.2 3.7 5.4e-16 58.5 3.7 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2711 PF10924.8 EGG06699.1 - 0.092 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) COesterase PF00135.28 EGG06701.1 - 1.2e-81 275.1 0.0 1.6e-81 274.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG06701.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lyase_aromatic PF00221.19 EGG06702.1 - 6.6e-06 25.1 0.0 8.3e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase BLOC1_2 PF10046.9 EGG06704.1 - 0.021 15.1 0.1 0.034 14.5 0.1 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.6 EGG06704.1 - 0.11 12.9 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Phage_Mu_Gam PF07352.12 EGG06706.1 - 0.039 13.9 0.0 0.15 11.9 0.0 2.0 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein UPF0181 PF03701.14 EGG06708.1 - 0.025 14.2 0.6 0.057 13.1 0.6 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Toprim PF01751.22 EGG06709.1 - 2.7e-10 40.4 0.0 4.7e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Toprim domain S-methyl_trans PF02574.16 EGG06711.1 - 6.1e-49 167.2 0.0 7.2e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Synaptonemal_3 PF15191.6 EGG06711.1 - 0.18 11.6 0.0 2 8.3 0.1 2.4 2 1 0 2 2 2 0 Synaptonemal complex central element protein 3 Chlorosome_CsmC PF11098.8 EGG06712.1 - 0.34 10.9 7.3 0.53 10.3 7.3 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C Coiled PF05710.12 EGG06712.1 - 3.4 8.6 19.5 4e+02 1.9 19.5 2.4 1 1 0 1 1 1 0 Coiled coil FAD_binding_7 PF03441.14 EGG06713.1 - 3.4e-55 186.6 1.7 6e-55 185.9 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EGG06713.1 - 3.9e-27 95.3 0.0 6.5e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase DUF148 PF02520.17 EGG06713.1 - 0.0045 17.1 0.2 0.01 15.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF148 RE_HindVP PF09519.10 EGG06713.1 - 0.14 11.2 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 HindVP restriction endonuclease Uso1_p115_head PF04869.14 EGG06714.1 - 9.3e-68 228.6 0.0 1.9e-67 227.7 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EGG06714.1 - 1.4e-09 38.4 23.2 3.8e-09 37.0 23.2 1.7 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Arm_vescicular PF18770.1 EGG06714.1 - 6.3e-05 22.8 0.0 0.00022 21.1 0.0 2.0 1 0 0 1 1 1 1 Armadillo tether-repeat of vescicular transport factor FlxA PF14282.6 EGG06714.1 - 0.0014 18.6 14.2 0.0038 17.2 14.2 1.7 1 0 0 1 1 1 1 FlxA-like protein Mod_r PF07200.13 EGG06714.1 - 0.22 11.6 14.0 0.6 10.2 14.0 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF3818 PF12825.7 EGG06714.1 - 0.34 9.9 5.3 0.58 9.1 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) ACCA PF03255.14 EGG06714.1 - 0.87 9.5 6.0 1.6 8.6 6.0 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF3781 PF12636.7 EGG06715.1 - 0.015 15.2 0.3 0.038 13.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF3225 PF11533.8 EGG06715.1 - 0.031 14.0 0.2 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3225) OAD_gamma PF04277.13 EGG06716.1 - 2.7 8.6 7.5 4.5 7.9 0.0 2.5 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain AAR2 PF05282.11 EGG06716.1 - 2.8 7.3 6.8 0.82 9.0 4.4 1.3 2 0 0 2 2 2 0 AAR2 protein Eapp_C PF10238.9 EGG06716.1 - 3.9 7.6 9.6 33 4.5 0.0 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein Cnn_1N PF07989.11 EGG06717.1 - 0.061 13.5 0.4 0.093 12.9 0.4 1.2 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 EGG06717.1 - 0.096 12.9 0.7 0.16 12.2 0.7 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Gastrin PF00918.17 EGG06717.1 - 0.1 13.6 0.5 0.18 12.8 0.5 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Gcn1_N PF12074.8 EGG06718.1 - 8e-48 163.5 3.2 4.7e-46 157.7 0.0 3.8 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 EGG06718.1 - 9.1e-31 103.3 27.4 0.013 15.7 0.1 20.5 25 0 0 25 25 19 7 HEAT repeat HEAT_2 PF13646.6 EGG06718.1 - 1.8e-24 85.9 49.8 5.1e-06 26.8 0.4 14.9 9 3 6 16 16 16 9 HEAT repeats HEAT_EZ PF13513.6 EGG06718.1 - 7.6e-23 80.6 36.3 0.00048 20.6 0.2 17.0 16 4 6 22 22 19 4 HEAT-like repeat Cnd1 PF12717.7 EGG06718.1 - 1.1e-15 58.1 0.4 0.0069 16.4 0.0 9.0 6 2 3 10 10 10 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGG06718.1 - 4.9e-12 45.9 0.1 2.2e-05 24.1 0.3 5.8 5 1 1 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 EGG06718.1 - 2.1e-08 34.7 0.0 0.54 10.9 0.0 7.6 4 2 4 8 8 8 1 Vacuolar 14 Fab1-binding region UME PF08064.13 EGG06718.1 - 8.1e-08 32.1 1.4 7.2 6.6 0.0 7.7 5 2 2 7 7 7 1 UME (NUC010) domain Adaptin_N PF01602.20 EGG06718.1 - 8.8e-08 31.1 10.3 0.003 16.2 2.2 6.8 7 1 0 7 7 7 2 Adaptin N terminal region RIX1 PF08167.12 EGG06718.1 - 1.3e-06 28.3 1.2 0.0031 17.3 0.0 5.5 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis Ecm29 PF13001.7 EGG06718.1 - 3.6e-06 25.9 9.3 1.6 7.3 0.1 7.6 8 1 0 8 8 8 3 Proteasome stabiliser DUF937 PF06078.11 EGG06718.1 - 0.00018 22.2 8.6 0.82 10.3 0.0 6.6 7 1 1 8 8 5 1 Bacterial protein of unknown function (DUF937) DUF3385 PF11865.8 EGG06718.1 - 0.00078 19.4 1.9 1e+02 2.8 0.0 7.4 6 3 2 8 8 8 0 Domain of unknown function (DUF3385) DUF3437 PF11919.8 EGG06718.1 - 0.0017 18.2 0.5 2.5 8.1 0.0 5.1 5 0 0 5 5 4 1 Domain of unknown function (DUF3437) Tti2 PF10521.9 EGG06718.1 - 0.0022 17.6 2.7 11 5.5 0.0 5.0 6 0 0 6 6 6 0 Tti2 family ParcG PF10274.9 EGG06718.1 - 0.0093 16.1 5.1 12 5.9 0.0 6.7 5 2 2 7 7 6 0 Parkin co-regulated protein MMS19_C PF12460.8 EGG06718.1 - 0.014 14.5 15.9 0.78 8.8 0.0 6.7 9 0 0 9 9 9 0 RNAPII transcription regulator C-terminal Cohesin_HEAT PF12765.7 EGG06718.1 - 0.024 15.0 0.6 19 5.7 0.0 4.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion API5 PF05918.11 EGG06718.1 - 0.029 13.2 1.1 8.6 5.0 0.0 4.3 5 0 0 5 5 5 0 Apoptosis inhibitory protein 5 (API5) Xpo1 PF08389.12 EGG06718.1 - 0.076 13.1 0.2 1.1e+02 2.8 0.0 4.7 4 0 0 4 4 4 0 Exportin 1-like protein Phage_TAC_9 PF10876.8 EGG06718.1 - 0.14 12.2 0.0 25 4.9 0.0 3.5 3 1 1 4 4 4 0 Phage tail assemb.y chaperone protein, TAC Arm PF00514.23 EGG06718.1 - 0.88 9.7 3.3 95 3.3 0.0 5.2 4 1 1 5 5 4 0 Armadillo/beta-catenin-like repeat FANCI_S2 PF14676.6 EGG06718.1 - 4.2 7.7 9.9 0.34 11.2 0.4 4.1 5 0 0 5 5 3 0 FANCI solenoid 2 TMEM154 PF15102.6 EGG06719.1 - 0.0086 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Y_phosphatase2 PF03162.13 EGG06721.1 - 4.6e-53 179.2 0.0 6.9e-53 178.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGG06721.1 - 6.3e-07 29.6 0.0 1e-06 28.9 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EGG06721.1 - 0.00024 20.9 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG06721.1 - 0.0011 18.5 0.1 0.0025 17.4 0.1 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Kri1 PF05178.12 EGG06722.1 - 4.5e-26 91.4 6.9 4.5e-26 91.4 6.9 5.2 6 1 0 6 6 6 1 KRI1-like family Kri1_C PF12936.7 EGG06722.1 - 3.9e-23 81.5 0.2 3.9e-23 81.5 0.2 3.8 4 0 0 4 4 4 1 KRI1-like family C-terminal Histone PF00125.24 EGG06723.1 - 1.1e-10 42.0 0.1 1.4e-10 41.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGG06723.1 - 0.042 14.2 0.1 0.044 14.2 0.1 1.3 1 1 0 1 1 1 0 CENP-S protein AsnA PF03590.15 EGG06724.1 - 0.034 13.9 0.6 0.082 12.6 0.6 1.6 1 0 0 1 1 1 0 Aspartate-ammonia ligase TMF_TATA_bd PF12325.8 EGG06724.1 - 0.19 12.0 4.7 0.14 12.4 0.7 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Pkinase PF00069.25 EGG06726.1 - 2.5e-67 227.1 0.0 4.1e-67 226.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG06726.1 - 2.3e-33 115.6 0.0 1.9e-25 89.7 0.1 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGG06726.1 - 0.0005 19.5 0.1 0.0035 16.7 0.0 2.2 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 EGG06726.1 - 0.0019 18.2 0.6 0.028 14.3 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGG06726.1 - 0.0095 14.8 0.0 0.03 13.1 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGG06726.1 - 0.036 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EGG06726.1 - 0.065 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EGG06726.1 - 0.17 11.4 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Rhomboid PF01694.22 EGG06729.1 - 1.7e-29 102.8 9.5 1.7e-29 102.8 9.5 1.8 2 0 0 2 2 2 1 Rhomboid family BMP2K_C PF15282.6 EGG06729.1 - 0.078 12.8 1.5 0.13 12.1 1.5 1.3 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus TIC20 PF16166.5 EGG06729.1 - 0.16 11.7 2.7 3.7 7.3 0.0 2.6 3 0 0 3 3 3 0 Chloroplast import apparatus Tic20-like Trp_repressor PF01371.19 EGG06730.1 - 0.15 12.2 0.0 1.7 8.9 0.0 2.1 1 1 1 2 2 2 0 Trp repressor protein DUF572 PF04502.13 EGG06731.1 - 1.1 8.8 23.3 1.7 8.2 23.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.9 EGG06731.1 - 2.4 6.6 20.1 3 6.3 20.1 1.1 1 0 0 1 1 1 0 Macoilin family TFIIF_alpha PF05793.12 EGG06731.1 - 4.3 5.8 47.2 5.9 5.4 47.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GREB1 PF15782.5 EGG06731.1 - 4.7 4.2 15.4 5.5 4.0 15.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MDFI PF15316.6 EGG06731.1 - 6 6.9 15.6 1.5 8.9 11.7 1.9 1 1 1 2 2 2 0 MyoD family inhibitor Ndc1_Nup PF09531.10 EGG06731.1 - 7.1 5.2 8.9 7.7 5.1 8.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LAP1C PF05609.12 EGG06731.1 - 7.6 5.5 23.9 10 5.1 23.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 EGG06731.1 - 9.2 4.3 37.2 16 3.5 37.2 1.3 1 0 0 1 1 1 0 Nop14-like family OrfB_IS605 PF01385.19 EGG06731.1 - 9.5 6.5 10.9 2.7 8.2 7.7 1.7 2 0 0 2 2 2 0 Probable transposase Aldo_ket_red PF00248.21 EGG06734.1 - 2.6e-53 181.1 0.0 3e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Evr1_Alr PF04777.13 EGG06735.1 - 1.1e-25 90.0 0.2 1.8e-25 89.3 0.2 1.4 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 EGG06735.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 APOBEC1 DUF4505 PF14956.6 EGG06736.1 - 3.3e-16 59.6 0.0 4.4e-16 59.1 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4505) Ribosomal_S19e PF01090.19 EGG06737.1 - 2.5e-57 192.4 0.1 2.8e-57 192.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Stork_head PF10264.9 EGG06738.1 - 0.089 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain zf-CCHC PF00098.23 EGG06739.1 - 0.037 14.1 1.7 0.037 14.1 1.7 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 EGG06739.1 - 0.19 11.6 0.3 0.38 10.6 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1764 PF08576.10 EGG06739.1 - 4.5 8.2 9.6 0.99 10.3 4.2 2.4 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) HI0933_like PF03486.14 EGG06740.1 - 0.031 13.0 0.0 0.038 12.7 0.0 1.0 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EGG06740.1 - 0.056 12.7 0.0 0.064 12.5 0.0 1.0 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 EGG06740.1 - 0.13 11.3 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 FAD binding domain DUF883 PF05957.13 EGG06741.1 - 8.7 7.0 10.1 0.74 10.5 0.1 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) G-alpha PF00503.20 EGG06743.1 - 3.6e-52 177.7 0.0 4.2e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGG06743.1 - 0.00051 19.5 0.0 0.00093 18.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG06743.1 - 0.096 12.2 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF3613 PF12266.8 EGG06745.1 - 0.014 15.1 0.2 3.6 7.4 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3613) HLH PF00010.26 EGG06746.1 - 1.1e-10 41.3 0.1 2.3e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sad1_UNC PF07738.13 EGG06747.1 - 9.2e-29 100.1 0.0 1.4e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal HALZ PF02183.18 EGG06749.1 - 0.037 14.2 0.1 0.061 13.6 0.1 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper His_Phos_1 PF00300.22 EGG06750.1 - 4.7e-13 49.3 0.1 1.2e-12 47.9 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CN_hydrolase PF00795.22 EGG06751.1 - 3.6e-39 134.7 0.0 4.9e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EGG06751.1 - 2.6e-21 75.9 0.0 7.5e-21 74.3 0.0 1.8 1 1 0 1 1 1 1 NAD synthase DUF3328 PF11807.8 EGG06754.1 - 0.074 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) CybS PF05328.12 EGG06755.1 - 5.6e-40 136.1 0.0 6.2e-40 136.0 0.0 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit LEA_4 PF02987.16 EGG06756.1 - 0.044 13.9 2.0 1.5 8.9 0.4 2.5 1 1 2 3 3 3 0 Late embryogenesis abundant protein ATP-synt_10 PF05176.14 EGG06757.1 - 6.5e-59 199.3 0.0 8e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Tim17 PF02466.19 EGG06758.1 - 4.8e-12 46.2 0.1 9e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RRM_1 PF00076.22 EGG06759.1 - 3.6e-14 52.3 0.0 5.4e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG06759.1 - 4.3e-05 23.1 0.0 6.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG06759.1 - 0.0032 17.4 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 EGG06759.1 - 0.025 14.8 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain RRM_occluded PF16842.5 EGG06759.1 - 0.051 13.4 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 EGG06759.1 - 0.19 11.8 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Glycos_transf_2 PF00535.26 EGG06760.1 - 8.1e-33 113.6 0.0 9.6e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGG06760.1 - 4e-12 46.5 0.0 5.2e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGG06760.1 - 0.0012 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 EGG06760.1 - 0.0045 16.5 0.0 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF5053 PF16476.5 EGG06761.1 - 0.089 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) DUF104 PF01954.16 EGG06762.1 - 0.041 14.3 0.2 7.9 7.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF104 PRIMA1 PF16101.5 EGG06763.1 - 0.2 11.7 1.7 0.51 10.4 1.7 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Cyto_heme_lyase PF01265.17 EGG06764.1 - 6.4e-73 245.9 14.0 7.8e-71 239.0 14.0 2.1 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Bystin PF05291.11 EGG06765.1 - 4.8e-133 442.9 0.5 5.4e-133 442.8 0.5 1.0 1 0 0 1 1 1 1 Bystin CxC1 PF18802.1 EGG06766.1 - 6.3e-30 103.4 0.0 1.4e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG06766.1 - 1.7e-09 37.8 0.0 5.2e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Pentaxin PF00354.17 EGG06767.1 - 0.04 13.6 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Pentaxin family CK2S PF15011.6 EGG06768.1 - 0.021 14.7 0.1 0.042 13.7 0.0 1.5 2 0 0 2 2 2 0 Casein Kinase 2 substrate RepB PF07506.11 EGG06768.1 - 0.093 12.8 0.6 0.16 12.0 0.2 1.6 2 0 0 2 2 2 0 RepB plasmid partitioning protein Nop14 PF04147.12 EGG06770.1 - 1.2 7.2 31.4 2.1 6.5 31.4 1.3 1 0 0 1 1 1 0 Nop14-like family L31 PF09784.9 EGG06770.1 - 1.3 9.4 5.6 3.3 8.2 5.6 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 GREB1 PF15782.5 EGG06770.1 - 5.3 4.0 19.4 7.1 3.6 19.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-CCHC PF00098.23 EGG06770.1 - 6 7.1 7.2 0.93 9.7 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle Retrotran_gag_2 PF14223.6 EGG06771.1 - 7.7e-05 22.4 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 EGG06771.1 - 0.14 12.3 3.2 0.09 12.9 0.8 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 EGG06771.1 - 0.31 10.9 3.2 0.53 10.2 3.2 1.3 1 0 0 1 1 1 0 Zinc knuckle Iso_dh PF00180.20 EGG06772.1 - 9.4e-117 390.0 0.0 1.1e-116 389.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_26 PF02156.15 EGG06773.1 - 0.0041 16.6 1.6 0.0041 16.6 1.6 1.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 26 ETAA1 PF15350.6 EGG06774.1 - 0.04 12.2 2.3 0.058 11.7 2.3 1.1 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue ParBc_2 PF08857.11 EGG06774.1 - 0.061 13.4 0.1 0.7 10.0 0.0 2.1 1 1 1 2 2 2 0 Putative ParB-like nuclease DAP3 PF10236.9 EGG06776.1 - 2.8e-40 138.4 0.0 3.1e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EGG06776.1 - 1.1e-07 32.3 0.0 1.9e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG06776.1 - 0.00052 20.3 0.0 0.003 17.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EGG06776.1 - 0.0015 17.8 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 EGG06776.1 - 0.0025 17.7 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EGG06776.1 - 0.0092 15.7 0.0 0.026 14.3 0.0 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain MeaB PF03308.16 EGG06776.1 - 0.0095 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EGG06776.1 - 0.0098 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 EGG06776.1 - 0.01 16.1 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EGG06776.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain NTPase_1 PF03266.15 EGG06776.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 EGG06776.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGG06776.1 - 0.027 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGG06776.1 - 0.036 14.6 0.0 0.069 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGG06776.1 - 0.05 13.3 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein cobW PF02492.19 EGG06776.1 - 0.055 13.1 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EGG06776.1 - 0.068 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EGG06776.1 - 0.069 13.6 0.0 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGG06776.1 - 0.071 13.1 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EGG06776.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 EGG06776.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 EGG06776.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain BTB PF00651.31 EGG06777.1 - 1.2e-11 44.9 0.2 3e-09 37.1 0.0 3.0 3 0 0 3 3 3 2 BTB/POZ domain CAP_GLY PF01302.25 EGG06777.1 - 1.1e-07 31.8 0.4 7.4e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 CAP-Gly domain Ribosomal_L30_N PF08079.12 EGG06778.1 - 6.2e-28 96.9 15.5 1.2e-27 96.0 15.5 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EGG06778.1 - 3.6e-17 62.0 1.1 9.7e-17 60.6 1.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e SHE3 PF17078.5 EGG06779.1 - 2.9e-07 30.5 38.3 4e-07 30.0 20.1 3.2 2 1 1 3 3 3 2 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 EGG06779.1 - 4.1e-06 27.2 8.1 4.1e-06 27.2 8.1 4.5 4 1 1 5 5 5 1 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 EGG06779.1 - 0.00047 19.5 11.5 0.00047 19.5 11.5 3.4 2 1 0 3 3 3 1 Protein of unknown function (DUF3450) HTH_5 PF01022.20 EGG06779.1 - 0.0028 17.5 0.2 0.008 16.0 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family RILP PF11461.8 EGG06779.1 - 0.026 14.7 0.5 0.026 14.7 0.5 3.6 3 0 0 3 3 3 0 Rab interacting lysosomal protein TSC22 PF01166.18 EGG06779.1 - 0.89 9.9 17.0 1.5 9.2 0.7 5.0 3 1 2 5 5 5 0 TSC-22/dip/bun family Fez1 PF06818.15 EGG06779.1 - 1.1 9.7 37.6 1.4 9.4 0.5 3.5 2 1 0 2 2 2 0 Fez1 DUF4407 PF14362.6 EGG06779.1 - 1.5 8.1 19.7 1.2 8.4 7.1 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4407) GAS PF13851.6 EGG06779.1 - 3.1 7.1 33.4 0.063 12.6 13.1 3.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding MCC-bdg_PDZ PF10506.9 EGG06779.1 - 4.7 7.3 14.4 0.18 11.8 3.0 3.3 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome GREB1 PF15782.5 EGG06780.1 - 0.066 10.3 3.0 0.082 10.0 3.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PilI PF10623.9 EGG06782.1 - 0.018 15.1 0.0 0.05 13.8 0.0 1.7 1 0 0 1 1 1 0 Plasmid conjugative transfer protein PilI Fer4_NifH PF00142.18 EGG06782.1 - 0.056 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Abhydrolase_1 PF00561.20 EGG06783.1 - 4e-39 134.8 0.0 5e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG06783.1 - 1.9e-13 50.3 0.0 1.1e-12 47.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG06783.1 - 3.1e-10 41.0 0.0 4.5e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 EGG06783.1 - 0.0019 17.1 0.0 0.0032 16.3 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_4 PF08386.10 EGG06783.1 - 0.0036 17.4 0.0 0.0069 16.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 EGG06783.1 - 0.0096 14.6 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 EGG06783.1 - 0.092 12.2 0.0 15 5.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 EGG06783.1 - 0.13 12.1 0.0 0.65 9.8 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase Pkinase PF00069.25 EGG06787.1 - 2e-43 148.7 0.2 3e-43 148.1 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG06787.1 - 2.4e-20 72.9 0.1 8.5e-20 71.1 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG06787.1 - 5.8e-05 22.6 0.0 8.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGG06787.1 - 0.00017 21.6 0.1 0.00024 21.1 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGG06787.1 - 0.0011 18.3 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGG06787.1 - 0.0015 18.2 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EGG06787.1 - 0.031 13.1 0.1 0.054 12.3 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EGG06787.1 - 0.041 13.5 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Histone PF00125.24 EGG06788.1 - 1.7e-18 67.2 0.0 2e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGG06788.1 - 5.2e-16 58.1 1.0 1e-15 57.2 1.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGG06788.1 - 1.4e-05 25.3 0.0 1.8e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Tnp_DNA_bind PF14706.6 EGG06789.1 - 0.081 12.8 0.7 0.41 10.5 0.1 2.5 3 0 0 3 3 3 0 Transposase DNA-binding Citrate_synt PF00285.21 EGG06789.1 - 0.11 11.5 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain CLZ PF16526.5 EGG06789.1 - 0.14 12.6 3.1 0.68 10.3 0.0 3.2 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Haspin_kinase PF12330.8 EGG06790.1 - 3.5e-22 78.9 0.0 1.1e-20 73.9 0.0 2.0 2 0 0 2 2 2 2 Haspin like kinase domain Abhydrolase_3 PF07859.13 EGG06792.1 - 1.1e-29 103.9 0.0 1.7e-21 77.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold IML1 PF12257.8 EGG06793.1 - 2.8e-96 322.0 0.2 4.4e-96 321.4 0.2 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EGG06793.1 - 6.1e-07 29.4 0.2 1.5e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Mito_carr PF00153.27 EGG06794.1 - 6.8e-76 250.3 0.9 2.3e-26 91.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.16 EGG06794.1 - 0.16 12.0 0.4 1.8 8.5 0.1 2.6 3 0 0 3 3 3 0 Colicin V production protein FF PF01846.19 EGG06796.1 - 1.6e-32 111.4 34.7 2.9e-12 46.6 0.6 6.4 6 0 0 6 6 6 5 FF domain WW PF00397.26 EGG06796.1 - 1.3e-12 47.6 14.4 1.4e-09 37.9 3.0 2.9 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 EGG06796.1 - 7.8e-07 29.7 12.3 0.00026 21.6 0.1 4.5 4 1 0 4 4 4 2 p190-A and -B Rho GAPs FF domain DIRP PF06584.13 EGG06796.1 - 0.066 13.4 0.1 0.066 13.4 0.1 4.3 4 1 1 5 5 5 0 DIRP FYVE PF01363.21 EGG06798.1 - 2.1e-14 53.4 5.1 2.5e-14 53.1 5.1 1.1 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 EGG06798.1 - 0.011 15.9 8.8 0.011 15.9 8.8 2.0 2 0 0 2 2 2 0 AN1-like Zinc finger SOG2 PF10428.9 EGG06799.1 - 7.8 5.6 15.2 9.6 5.3 15.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein LRR_8 PF13855.6 EGG06800.1 - 1.9e-06 27.5 9.1 1.9e-06 27.5 9.1 3.6 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 EGG06800.1 - 2.1e-06 27.9 16.7 0.0016 18.8 1.8 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGG06800.1 - 0.025 14.1 5.6 0.061 12.8 4.8 2.0 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 EGG06800.1 - 0.18 12.5 13.5 12 6.9 0.6 6.1 4 1 0 4 4 4 0 Leucine Rich Repeat Alpha_kinase PF02816.18 EGG06803.1 - 2.3e-07 31.1 0.9 2.9e-07 30.8 0.8 1.3 1 1 0 1 1 1 1 Alpha-kinase family DUF4297 PF14130.6 EGG06803.1 - 0.047 13.8 0.1 0.068 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) SKI PF01202.22 EGG06806.1 - 0.026 14.6 0.1 0.083 13.0 0.0 1.7 2 0 0 2 2 2 0 Shikimate kinase GFA PF04828.14 EGG06807.1 - 0.096 13.0 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme TFIIF_beta PF02270.15 EGG06808.1 - 1.7e-29 101.8 0.3 1.4e-27 95.6 0.1 2.2 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 EGG06808.1 - 2.7e-26 92.9 0.8 5e-26 92.0 0.0 1.8 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus CENP-Q PF13094.6 EGG06808.1 - 0.036 14.3 0.2 0.058 13.6 0.2 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit PGA2 PF07543.12 EGG06808.1 - 0.045 13.7 0.5 0.045 13.7 0.5 1.6 2 0 0 2 2 2 0 Protein trafficking PGA2 Tau95 PF09734.9 EGG06808.1 - 0.069 14.0 0.3 0.16 12.8 0.3 1.8 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DNA_pol_phi PF04931.13 EGG06808.1 - 0.45 8.6 4.1 0.7 7.9 4.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi KAR9 PF08580.10 EGG06812.1 - 0.19 10.2 16.8 0.21 10.1 16.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 VIT1 PF01988.19 EGG06813.1 - 4.3e-50 170.6 2.5 4.7e-50 170.4 2.5 1.0 1 0 0 1 1 1 1 VIT family DUF308 PF03729.13 EGG06813.1 - 0.019 15.3 7.4 0.034 14.5 3.1 2.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Profilin PF00235.19 EGG06816.1 - 5.1e-43 146.4 0.1 5.6e-43 146.2 0.1 1.0 1 0 0 1 1 1 1 Profilin Myb_DNA-bind_4 PF13837.6 EGG06817.1 - 0.024 15.0 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain TFIIE_beta PF02186.15 EGG06819.1 - 0.021 15.1 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 TFIIE beta subunit core domain RE_XcyI PF09571.10 EGG06819.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 XcyI restriction endonuclease Cyt-b5 PF00173.28 EGG06820.1 - 4.1e-18 65.3 0.0 5.5e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Neuropeptide_S PF14993.6 EGG06821.1 - 0.068 13.0 0.7 15 5.5 0.1 2.5 2 0 0 2 2 2 0 Neuropeptide S precursor protein Cutinase PF01083.22 EGG06822.1 - 2.7e-26 92.6 1.4 3.3e-26 92.3 1.4 1.1 1 0 0 1 1 1 1 Cutinase Pmp3 PF01679.17 EGG06823.1 - 1.3e-12 47.7 4.3 2.1e-12 47.0 4.2 1.4 1 1 0 1 1 1 1 Proteolipid membrane potential modulator PBP1_TM PF14812.6 EGG06823.1 - 1.6 9.2 6.0 4.5 7.7 0.8 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ICL PF00463.21 EGG06825.1 - 0.0022 16.6 0.0 0.02 13.4 0.0 1.9 1 1 1 2 2 2 2 Isocitrate lyase family CheW PF01584.19 EGG06825.1 - 0.098 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 CheW-like domain Proteasome PF00227.26 EGG06826.1 - 2.9e-51 173.7 0.0 3.4e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGG06826.1 - 5.4e-13 48.4 1.7 1e-12 47.4 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature COesterase PF00135.28 EGG06827.1 - 2.6e-87 293.9 0.0 3.4e-87 293.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EGG06827.1 - 0.0035 16.9 0.5 0.0052 16.3 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGG06827.1 - 0.006 16.5 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold CAP59_mtransfer PF11735.8 EGG06828.1 - 9e-15 55.0 0.0 1.5e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 FAM124 PF15067.6 EGG06828.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 FAM124 family BOP1NT PF08145.12 EGG06830.1 - 7.9e-109 363.6 3.9 7.9e-109 363.6 3.9 1.6 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 EGG06830.1 - 8.5e-15 54.9 0.5 0.0033 18.2 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat IKI3 PF04762.12 EGG06830.1 - 0.0012 16.9 0.0 0.0017 16.5 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EGG06830.1 - 0.025 14.9 0.1 0.93 9.8 0.1 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PI-PLC-X PF00388.19 EGG06831.1 - 2.2e-10 40.3 0.0 1.1e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain Bac_surface_Ag PF01103.23 EGG06831.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Surface antigen DUF2684 PF10885.8 EGG06832.1 - 0.075 13.2 2.0 7.6 6.7 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2684) RRP36 PF06102.12 EGG06833.1 - 1.8e-05 24.7 6.1 1.8e-05 24.7 6.1 1.0 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 TPP_enzyme_N PF02776.18 EGG06838.1 - 5.6e-35 120.5 0.0 8.5e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGG06838.1 - 1.2e-17 63.9 0.0 3.3e-17 62.5 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EGG06838.1 - 2.8e-14 53.2 0.0 4.8e-13 49.2 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peripla_BP_4 PF13407.6 EGG06838.1 - 0.018 14.7 0.0 0.051 13.1 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding protein domain DXP_synthase_N PF13292.6 EGG06838.1 - 0.062 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_N PF02776.18 EGG06839.1 - 4.3e-35 120.8 0.0 6.3e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGG06839.1 - 1.8e-20 73.1 0.0 4.3e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EGG06839.1 - 1.6e-13 50.7 0.0 1.3e-12 47.8 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EGG06839.1 - 0.0076 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Peripla_BP_4 PF13407.6 EGG06839.1 - 0.016 14.8 0.0 0.047 13.3 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding protein domain Hydrolase_4 PF12146.8 EGG06840.1 - 1.9e-14 53.5 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG06840.1 - 3.3e-14 53.2 0.0 4.7e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG06840.1 - 5.8e-08 33.6 0.0 6.3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EGG06840.1 - 0.0045 16.8 0.1 0.034 14.0 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 EGG06840.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 EGG06840.1 - 0.026 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 EGG06840.1 - 0.098 12.3 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Putative esterase DUF5535 PF17687.1 EGG06840.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5535) UPF0227 PF05728.12 EGG06840.1 - 0.15 11.9 0.0 1.1 9.2 0.0 2.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0227) Pkinase PF00069.25 EGG06842.1 - 7.9e-61 205.7 0.0 1.1e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG06842.1 - 3.8e-34 118.1 0.0 4.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG06842.1 - 0.0041 16.1 0.6 0.0069 15.4 0.6 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGG06842.1 - 0.065 12.5 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Iso_dh PF00180.20 EGG06843.1 - 5.6e-82 275.7 0.0 1.4e-81 274.3 0.0 1.6 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-CCHC_4 PF14392.6 EGG06845.1 - 0.19 11.5 0.7 0.56 10.0 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle OPT PF03169.15 EGG06846.1 - 6.8e-68 229.8 36.2 1.7e-66 225.2 36.2 2.2 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Lactamase_B_2 PF12706.7 EGG06849.1 - 3.7e-25 88.6 0.1 7.7e-25 87.6 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGG06849.1 - 1.9e-06 28.1 1.9 3.4e-06 27.2 1.9 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EGG06849.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Longin PF13774.6 EGG06857.1 - 0.047 13.7 0.1 0.085 12.9 0.1 1.3 1 0 0 1 1 1 0 Regulated-SNARE-like domain Spore_YpjB PF09577.10 EGG06858.1 - 0.0014 18.5 0.6 0.0019 18.1 0.6 1.2 1 0 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) Nop14 PF04147.12 EGG06858.1 - 0.076 11.2 10.0 0.079 11.2 10.0 1.2 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 EGG06858.1 - 2.9 7.0 9.7 5 6.2 9.7 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Actin PF00022.19 EGG06861.1 - 2.5e-118 395.2 0.0 7.8e-118 393.6 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGG06861.1 - 0.0032 16.3 0.3 1.3 7.8 0.0 2.5 3 0 0 3 3 3 2 MreB/Mbl protein Spo12 PF05032.12 EGG06862.1 - 1.8e-10 40.5 0.2 3.9e-10 39.5 0.2 1.5 1 0 0 1 1 1 1 Spo12 family DUF3684 PF12449.8 EGG06864.1 - 0 1217.9 0.1 0 1217.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EGG06864.1 - 0.016 15.1 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RRM_DME PF15628.6 EGG06864.1 - 0.16 12.1 0.1 0.88 9.8 0.0 2.3 2 0 0 2 2 2 0 RRM in Demeter FAD_binding_1 PF00667.20 EGG06865.1 - 1.2e-28 100.3 0.8 1.3e-19 70.7 0.0 3.1 2 1 1 3 3 3 2 FAD binding domain NAD_binding_1 PF00175.21 EGG06865.1 - 2.5e-07 31.3 0.0 8.1e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain aGPT-Pplase2 PF18724.1 EGG06865.1 - 0.0031 17.3 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 cwf21 PF08312.12 EGG06866.1 - 1.5e-13 50.7 8.0 1.5e-13 50.7 8.0 1.9 2 0 0 2 2 2 1 cwf21 domain DUF2052 PF09747.9 EGG06869.1 - 0.02 15.0 5.4 0.027 14.6 5.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DNA_pol_phi PF04931.13 EGG06869.1 - 0.044 11.9 4.8 0.045 11.9 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EGG06869.1 - 0.055 12.8 6.5 0.076 12.3 6.5 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EGG06869.1 - 0.17 12.3 13.6 0.34 11.3 13.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 EGG06869.1 - 0.18 12.0 8.5 0.4 10.9 8.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) EBV-NA3 PF05009.12 EGG06869.1 - 0.22 11.0 4.3 0.54 9.7 3.3 1.9 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RXT2_N PF08595.11 EGG06869.1 - 0.3 11.1 10.1 0.55 10.2 9.9 1.6 1 1 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 EGG06869.1 - 0.31 9.3 5.6 0.31 9.3 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.11 EGG06869.1 - 1.2 9.0 6.4 2 8.3 6.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PBP1_TM PF14812.6 EGG06869.1 - 1.3 9.4 13.9 0.31 11.4 9.9 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PUFD PF16553.5 EGG06870.1 - 0.027 14.6 0.1 0.071 13.2 0.1 1.6 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain Spexin PF15171.6 EGG06871.1 - 0.013 15.6 0.1 0.02 15.1 0.1 1.2 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin DS PF01916.17 EGG06875.1 - 2.9e-127 423.9 0.0 3.4e-127 423.6 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase Ammonium_transp PF00909.21 EGG06876.1 - 5.9e-99 331.5 24.8 7.1e-99 331.2 24.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Snf7 PF03357.21 EGG06877.1 - 6e-39 133.4 16.9 7e-39 133.2 16.9 1.0 1 0 0 1 1 1 1 Snf7 AP1AR PF15745.5 EGG06877.1 - 0.0088 15.7 3.1 0.011 15.4 3.1 1.2 1 0 0 1 1 1 1 AP-1 complex-associated regulatory protein AAA_12 PF13087.6 EGG06877.1 - 0.045 13.4 2.5 0.067 12.8 2.5 1.2 1 0 0 1 1 1 0 AAA domain DUF2117 PF09890.9 EGG06877.1 - 0.053 13.0 0.4 0.074 12.5 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) V_ATPase_I PF01496.19 EGG06877.1 - 0.11 10.3 7.1 0.13 10.1 7.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin PF02996.17 EGG06877.1 - 0.18 11.7 10.3 1.3 9.0 1.9 2.9 2 1 1 3 3 3 0 Prefoldin subunit NPV_P10 PF05531.12 EGG06877.1 - 0.19 12.2 5.1 5.2 7.6 1.6 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Rx_N PF18052.1 EGG06877.1 - 0.21 11.9 6.1 0.32 11.3 2.0 2.5 1 1 1 2 2 2 0 Rx N-terminal domain FapA PF03961.13 EGG06877.1 - 0.26 9.9 12.2 0.15 10.7 4.7 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 EGG06877.1 - 0.34 11.3 12.6 0.59 10.5 7.6 2.2 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2730 PF10805.8 EGG06877.1 - 0.98 9.5 8.4 0.64 10.1 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) FlgT_N PF16548.5 EGG06877.1 - 1.6 9.3 7.4 0.28 11.8 1.7 2.4 1 1 2 3 3 3 0 Flagellar assembly protein T, N-terminal domain NuA4 PF09340.10 EGG06877.1 - 2.2 8.2 7.0 1.4 8.9 1.8 2.8 3 1 0 3 3 3 0 Histone acetyltransferase subunit NuA4 GrpE PF01025.19 EGG06877.1 - 2.4 7.8 9.8 5.3 6.7 9.8 1.6 1 1 0 1 1 1 0 GrpE DUF948 PF06103.11 EGG06877.1 - 2.6 8.4 7.1 39 4.6 7.1 2.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) RPW8 PF05659.11 EGG06877.1 - 3.9 7.2 10.3 2.6 7.7 7.4 2.1 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 APG6_N PF17675.1 EGG06877.1 - 4.8 7.7 13.2 10 6.7 8.1 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region BST2 PF16716.5 EGG06877.1 - 4.9 7.8 10.3 46 4.7 6.7 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Fib_alpha PF08702.10 EGG06877.1 - 9.1 6.5 14.9 14 5.8 0.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Alpha_kinase PF02816.18 EGG06879.1 - 1.2e-07 32.1 0.1 3.8e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 Alpha-kinase family Ras PF00071.22 EGG06882.1 - 4.9e-34 117.3 0.0 5.8e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG06882.1 - 3.8e-10 40.0 0.0 5.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG06882.1 - 0.0014 18.2 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 EGG06882.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Glyco_hydro_18 PF00704.28 EGG06884.1 - 3e-57 194.7 0.0 3.5e-57 194.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_114 PF03537.13 EGG06884.1 - 0.059 12.7 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 LAT PF15234.6 EGG06885.1 - 0.39 10.4 3.1 0.39 10.4 3.1 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells RRP36 PF06102.12 EGG06886.1 - 6.7e-48 162.8 18.9 6.7e-48 162.8 18.9 1.7 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 Trypan_PARP PF05887.11 EGG06886.1 - 0.013 15.5 5.4 0.028 14.4 5.4 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) tRNA_lig_kinase PF08303.11 EGG06886.1 - 0.59 10.2 5.0 0.14 12.3 0.6 2.1 2 1 1 3 3 3 0 tRNA ligase kinase domain DUF543 PF04418.12 EGG06887.1 - 3.3e-11 43.0 0.1 3.8e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Lipase_3 PF01764.25 EGG06888.1 - 1.3e-16 60.8 0.0 2.4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) MAP7 PF05672.11 EGG06888.1 - 0.016 14.9 1.9 0.029 14.1 1.9 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF676 PF05057.14 EGG06888.1 - 0.062 12.8 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) COesterase PF00135.28 EGG06889.1 - 4.2e-23 82.0 0.0 5.1e-21 75.1 0.0 2.2 1 1 1 2 2 2 2 Carboxylesterase family COesterase PF00135.28 EGG06890.1 - 6.8e-24 84.6 0.1 7.1e-24 84.5 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG06890.1 - 0.00094 19.1 0.0 0.001 19.0 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG06890.1 - 0.0043 16.6 0.0 0.0043 16.6 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EGG06891.1 - 1e-08 34.5 0.0 1.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family bZIP_1 PF00170.21 EGG06893.1 - 2.4e-12 46.7 9.0 5.4e-12 45.6 9.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.8 EGG06893.1 - 1e-06 29.1 1.3 1e-06 29.1 1.3 3.1 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain Aft1_HRA PF11786.8 EGG06893.1 - 1.6e-06 28.3 5.9 1.6e-06 28.3 5.9 6.0 4 3 2 6 6 6 1 Aft1 HRA domain bZIP_2 PF07716.15 EGG06893.1 - 2.8e-05 24.1 9.4 2.8e-05 24.1 9.4 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGG06893.1 - 0.0036 17.8 2.2 0.0036 17.8 2.2 3.1 3 0 0 3 3 3 1 bZIP Maf transcription factor HALZ PF02183.18 EGG06893.1 - 0.084 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Nop53 PF07767.11 EGG06893.1 - 0.13 11.6 8.1 0.23 10.8 8.1 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SET PF00856.28 EGG06895.1 - 3.7e-08 34.0 2.6 1.4e-06 28.8 0.0 3.4 2 2 0 2 2 2 1 SET domain Podoplanin PF05808.11 EGG06895.1 - 0.56 10.3 5.5 0.12 12.5 0.4 2.4 2 0 0 2 2 2 0 Podoplanin Innate_immun PF12782.7 EGG06896.1 - 4.8 6.6 8.1 5.8 6.3 8.1 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family PWWP PF00855.17 EGG06898.1 - 1.5e-05 25.3 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 PWWP domain Actin PF00022.19 EGG06899.1 - 0.17 10.4 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Actin HTH_33 PF13592.6 EGG06902.1 - 0.0089 15.7 1.1 0.069 12.8 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix Menin PF05053.13 EGG06910.1 - 1.5 7.1 5.8 2.2 6.6 5.8 1.1 1 0 0 1 1 1 0 Menin ATP_bind_1 PF03029.17 EGG06912.1 - 1.8e-81 273.5 0.0 2.2e-81 273.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EGG06912.1 - 0.0003 20.6 0.0 0.055 13.3 0.0 2.3 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop GTP_EFTU PF00009.27 EGG06912.1 - 0.00077 19.0 0.0 0.02 14.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EGG06912.1 - 0.0044 17.6 0.1 0.0089 16.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGG06912.1 - 0.0046 16.7 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG06912.1 - 0.0056 16.8 0.0 0.0094 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EGG06912.1 - 0.0077 16.3 0.0 0.012 15.6 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.18 EGG06912.1 - 0.0091 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SSE PF00437.20 EGG06912.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EGG06912.1 - 0.02 15.2 0.2 0.09 13.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGG06912.1 - 0.021 15.2 0.0 0.045 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EGG06912.1 - 0.03 14.7 0.0 0.084 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGG06912.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 EGG06912.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_25 PF13481.6 EGG06912.1 - 0.081 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGG06912.1 - 0.094 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 EGG06912.1 - 0.099 12.0 0.1 0.83 9.0 0.1 2.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 EGG06912.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 EGG06912.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EGG06912.1 - 0.12 12.3 0.1 1.8 8.5 0.0 2.7 3 1 0 3 3 3 0 RsgA GTPase NTPase_1 PF03266.15 EGG06912.1 - 0.13 12.2 0.0 2.8 7.8 0.0 2.3 3 0 0 3 3 2 0 NTPase AAA_31 PF13614.6 EGG06912.1 - 0.13 12.1 0.0 0.67 9.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EGG06912.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EGG06912.1 - 0.16 12.1 0.0 1.3 9.1 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase CobU PF02283.16 EGG06912.1 - 0.23 11.0 0.1 0.57 9.7 0.0 1.7 2 0 0 2 2 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Ribosomal_S3Ae PF01015.18 EGG06914.1 - 4.7e-92 307.1 2.4 5.8e-92 306.8 2.4 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family NEMO PF11577.8 EGG06914.1 - 0.014 15.4 0.1 0.031 14.3 0.1 1.5 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO MRP-L27 PF09809.9 EGG06914.1 - 0.048 13.5 0.1 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L27 Tab2_like PF06485.11 EGG06914.1 - 0.079 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 LMP PF04778.12 EGG06914.1 - 0.082 12.8 0.4 0.082 12.8 0.4 1.6 2 0 0 2 2 2 0 LMP repeated region TipAS PF07739.13 EGG06914.1 - 0.094 13.3 0.1 0.88 10.1 0.0 2.4 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Abhydro_lipase PF04083.16 EGG06914.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Allexi_40kDa PF05549.11 EGG06915.1 - 0.027 14.0 0.3 0.58 9.6 0.4 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein AAA_12 PF13087.6 EGG06916.1 - 5.3e-30 104.5 0.3 9.6e-30 103.7 0.3 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGG06916.1 - 0.032 14.0 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase GCP_C_terminal PF04130.13 EGG06918.1 - 0.00044 19.8 0.0 0.0005 19.6 0.0 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Cutinase PF01083.22 EGG06919.1 - 1.5e-26 93.5 3.0 2.1e-26 92.9 3.0 1.2 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 EGG06919.1 - 0.00096 19.1 0.1 0.002 18.1 0.0 1.4 2 0 0 2 2 2 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 EGG06919.1 - 0.0046 16.6 0.0 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_8 PF06259.12 EGG06919.1 - 0.027 14.1 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Lactamase_B_2 PF12706.7 EGG06920.1 - 2.3e-23 82.8 0.0 4.9e-23 81.7 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGG06920.1 - 2e-06 27.9 0.2 5.6e-06 26.5 0.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EGG06920.1 - 0.092 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain E1-E2_ATPase PF00122.20 EGG06922.1 - 4.4e-37 127.4 1.4 1e-19 70.8 0.0 2.5 2 1 1 3 3 3 2 E1-E2 ATPase DUF2127 PF09900.9 EGG06922.1 - 0.001 19.3 1.7 0.0029 17.9 1.7 1.7 1 1 0 1 1 1 1 Predicted membrane protein (DUF2127) Spore_coat_CotO PF14153.6 EGG06925.1 - 0.41 10.5 8.8 0.052 13.5 4.2 1.8 2 0 0 2 2 2 0 Spore coat protein CotO FAM176 PF14851.6 EGG06925.1 - 0.81 9.3 4.8 2.5 7.7 4.8 1.8 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 EGG06925.1 - 1.4 9.3 11.4 4.5 7.7 11.4 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 EGG06925.1 - 2.7 7.2 11.8 6.1 6.1 11.8 1.5 1 0 0 1 1 1 0 NOA36 protein CxC1 PF18802.1 EGG06927.1 - 2e-10 40.8 0.0 3.7e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG06927.1 - 0.0018 18.4 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases ABC_tran_CTD PF16326.5 EGG06927.1 - 0.015 15.6 0.1 0.63 10.3 0.1 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain CxC3 PF18804.1 EGG06927.1 - 0.23 11.3 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases GHMP_kinases_N PF00288.26 EGG06929.1 - 5.1e-07 29.8 0.0 9.6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cytochrom_B562 PF07361.11 EGG06930.1 - 0.16 12.6 0.5 0.35 11.5 0.5 1.5 1 0 0 1 1 1 0 Cytochrome b562 HeLo PF14479.6 EGG06930.1 - 0.19 11.6 0.7 0.4 10.5 0.7 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation IGPD PF00475.18 EGG06931.1 - 3.8e-55 186.2 1.0 4.9e-55 185.8 1.0 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DEAD PF00270.29 EGG06932.1 - 4.3e-39 134.1 0.0 7.8e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG06932.1 - 9.3e-22 77.5 0.0 1.2e-18 67.5 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGG06932.1 - 7e-19 67.8 0.0 1.5e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGG06932.1 - 0.00021 21.3 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGG06932.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 EGG06932.1 - 0.087 13.1 0.3 0.68 10.2 0.3 2.2 1 1 0 1 1 1 0 AAA domain BLYB PF05289.11 EGG06932.1 - 0.23 11.7 1.8 0.32 11.2 0.4 1.9 2 0 0 2 2 2 0 Borrelia hemolysin accessory protein Macoilin PF09726.9 EGG06934.1 - 0.25 9.9 6.5 0.32 9.5 6.5 1.1 1 0 0 1 1 1 0 Macoilin family DUF2015 PF09435.10 EGG06935.1 - 7e-12 45.2 0.1 9.3e-12 44.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Mito_fiss_reg PF05308.11 EGG06935.1 - 0.091 12.8 1.3 0.11 12.5 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator FDC-SP PF15215.6 EGG06936.1 - 0.16 12.6 0.3 0.19 12.3 0.3 1.1 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide B_solenoid_ydck PF18836.1 EGG06937.1 - 0.014 15.2 1.0 51 4.0 0.0 4.1 2 1 2 4 4 4 0 Beta solenoid repeat from YDCK Hexapep PF00132.24 EGG06937.1 - 0.03 14.0 0.1 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Chitin_synth_1 PF01644.17 EGG06938.1 - 6.7e-69 231.0 0.0 1e-68 230.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGG06938.1 - 3.8e-27 94.0 0.0 6.9e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGG06938.1 - 4.1e-25 88.4 0.1 7.3e-20 71.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGG06938.1 - 1.7e-08 34.6 4.2 1.7e-08 34.6 4.2 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Arrestin_C PF02752.22 EGG06939.1 - 5.7e-12 46.2 0.1 5.7e-12 46.2 0.1 3.0 4 0 0 4 4 4 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGG06939.1 - 5.2e-06 26.6 0.3 0.093 12.8 0.0 3.3 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain MCM PF00493.23 EGG06941.1 - 2.2e-75 252.6 3.4 1.7e-62 210.5 1.3 2.3 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 EGG06941.1 - 6.7e-37 126.2 0.2 1.2e-36 125.3 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGG06941.1 - 6.1e-11 42.6 0.1 1.7e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGG06941.1 - 4e-07 29.6 0.0 7.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI MCM6_C PF18263.1 EGG06941.1 - 0.0001 22.5 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 EGG06941.1 - 0.00023 21.7 0.5 0.00081 19.9 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Sigma54_activat PF00158.26 EGG06941.1 - 0.022 14.5 0.1 0.06 13.0 0.1 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Polyoma_coat2 PF00761.20 EGG06941.1 - 0.18 11.5 0.6 0.34 10.6 0.6 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein zf-C3HC4_5 PF17121.5 EGG06943.1 - 0.099 12.5 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3987 PF13148.6 EGG06946.1 - 0.0018 17.4 0.0 0.053 12.5 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) LRR_4 PF12799.7 EGG06947.1 - 0.024 15.1 0.4 0.33 11.4 0.1 3.1 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) F-box PF00646.33 EGG06947.1 - 0.097 12.6 0.3 0.45 10.4 0.3 2.1 1 1 0 1 1 1 0 F-box domain Cyclin_N PF00134.23 EGG06949.1 - 1.1e-06 28.4 0.3 2e-06 27.6 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Aminotran_1_2 PF00155.21 EGG06950.1 - 3.9e-41 141.4 0.0 5.8e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGG06950.1 - 0.037 13.3 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase NUMOD1 PF07453.13 EGG06950.1 - 0.18 12.1 0.0 0.94 9.8 0.0 2.1 2 0 0 2 2 2 0 NUMOD1 domain Aminotran_1_2 PF00155.21 EGG06952.1 - 1.4e-36 126.5 0.0 1.8e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II NPR3 PF03666.13 EGG06954.1 - 3.9e-25 88.6 0.3 9.1e-25 87.4 0.3 1.6 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 HMG_box PF00505.19 EGG06955.1 - 0.0046 17.3 0.2 0.2 12.1 0.1 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box CxC6 PF18721.1 EGG06956.1 - 2.5e-19 69.3 3.1 5.8e-19 68.1 3.1 1.6 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases WD40 PF00400.32 EGG06958.1 - 5.3e-34 115.7 23.7 5.1e-06 27.1 0.0 12.7 13 0 0 13 13 12 7 WD domain, G-beta repeat Utp12 PF04003.12 EGG06958.1 - 1.6e-23 83.1 0.4 2.9e-23 82.2 0.4 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EGG06958.1 - 1.1e-19 70.5 0.0 0.01 16.2 0.1 8.9 4 2 8 12 12 11 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGG06958.1 - 4.4e-07 29.7 0.0 0.9 9.6 0.0 5.8 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EGG06958.1 - 2.2e-06 26.8 1.1 0.88 8.5 0.0 4.9 4 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGG06958.1 - 2.8e-05 23.6 0.0 0.0011 18.4 0.0 3.0 3 0 0 3 3 3 1 WD40-like domain eIF2A PF08662.11 EGG06958.1 - 0.00034 20.6 6.4 0.94 9.3 0.2 5.5 2 2 4 6 6 6 2 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 EGG06958.1 - 0.0098 15.2 0.0 0.17 11.1 0.0 2.8 3 1 1 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ PF01011.21 EGG06958.1 - 0.015 15.2 0.1 34 4.6 0.0 4.6 4 0 0 4 4 4 0 PQQ enzyme repeat Nbas_N PF15492.6 EGG06958.1 - 0.038 13.3 1.3 1.9 7.7 0.0 3.8 3 3 2 5 5 5 0 Neuroblastoma-amplified sequence, N terminal RPN1_RPN2_N PF17781.1 EGG06958.1 - 0.078 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain RRM_1 PF00076.22 EGG06958.1 - 0.13 12.1 0.1 0.4 10.5 0.1 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PQQ_3 PF13570.6 EGG06958.1 - 2.3 8.8 5.3 72 4.1 0.0 4.7 5 0 0 5 5 4 0 PQQ-like domain TFIIE_alpha PF02002.17 EGG06959.1 - 4.7e-16 58.5 0.6 8.6e-16 57.7 0.6 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 EGG06959.1 - 0.00024 21.3 0.6 0.00057 20.1 0.6 1.6 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 EGG06959.1 - 0.0041 16.6 1.0 0.0076 15.7 1.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding GntR PF00392.21 EGG06959.1 - 0.024 14.3 0.2 0.044 13.4 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family zf_UBZ PF18439.1 EGG06959.1 - 0.032 13.8 1.2 2.9 7.5 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger ADK_lid PF05191.14 EGG06959.1 - 0.047 13.7 0.3 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-RING_4 PF14570.6 EGG06959.1 - 0.68 9.8 4.8 1.8 8.4 0.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain GST_N_2 PF13409.6 EGG06960.1 - 9.8e-22 77.0 0.0 2.3e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGG06960.1 - 4.8e-14 52.1 0.0 8.4e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG06960.1 - 1.6e-08 34.7 0.0 3.7e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGG06960.1 - 2.4e-05 24.6 0.0 0.036 14.5 0.0 2.6 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGG06960.1 - 2.5e-05 24.4 0.0 5.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGG06960.1 - 0.00017 21.3 0.0 0.00037 20.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 EGG06962.1 - 9.8e-14 51.5 20.1 0.00032 21.4 0.2 6.6 6 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG06962.1 - 6.6e-10 39.2 0.2 0.0002 21.6 0.0 4.3 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG06962.1 - 0.015 15.1 0.2 0.6 10.0 0.0 2.7 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 EGG06962.1 - 0.027 13.2 2.2 0.96 8.1 0.2 2.9 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Med13_C PF06333.12 EGG06963.1 - 0.77 9.0 9.1 1.2 8.4 9.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DUF4820 PF16091.5 EGG06963.1 - 8.8 5.6 13.3 16 4.8 13.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) HSF_DNA-bind PF00447.17 EGG06964.1 - 3.4e-22 78.9 1.5 3.5e-22 78.8 1.5 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Cdc6_C PF09079.11 EGG06964.1 - 0.14 12.2 0.0 0.15 12.1 0.0 1.3 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain UQ_con PF00179.26 EGG06965.1 - 1.3e-52 177.2 0.0 1.4e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGG06965.1 - 0.015 15.5 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EGG06965.1 - 0.019 14.8 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 EGG06965.1 - 0.056 13.1 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B PSS PF03034.15 EGG06966.1 - 5.2e-108 360.9 14.6 7.8e-108 360.4 14.6 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase Prominin PF05478.11 EGG06967.1 - 0.21 9.5 3.4 0.34 8.8 3.4 1.3 1 0 0 1 1 1 0 Prominin Fungal_TACC PF12709.7 EGG06967.1 - 0.43 11.0 4.5 0.49 10.9 1.7 2.5 3 1 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins HIP1_clath_bdg PF16515.5 EGG06967.1 - 3.6 8.3 10.2 0.54 10.9 4.8 2.3 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DnaGprimase_HBD PF16730.5 EGG06968.1 - 0.05 13.7 2.0 0.063 13.4 2.0 1.3 1 1 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain Cript PF10235.9 EGG06969.1 - 3.5e-26 91.6 10.5 3.5e-26 91.6 10.5 2.2 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT Rhodanese_C PF12368.8 EGG06969.1 - 0.085 13.2 6.9 0.09 13.2 2.4 2.2 2 0 0 2 2 2 0 Rhodanase C-terminal DZR PF12773.7 EGG06969.1 - 0.15 12.1 12.1 0.33 11.0 7.5 2.8 1 1 1 2 2 2 0 Double zinc ribbon DUF2039 PF10217.9 EGG06969.1 - 0.24 11.8 13.1 0.14 12.5 7.8 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zinc_ribbon_2 PF13240.6 EGG06969.1 - 0.56 10.0 14.8 2.5 8.0 0.5 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DUF1272 PF06906.11 EGG06969.1 - 0.68 10.1 6.1 11 6.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf_UBZ PF18439.1 EGG06969.1 - 1 9.0 0.1 1 9.0 0.1 3.1 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 EGG06969.1 - 1.5 9.6 12.3 5 8.0 8.4 2.8 2 1 0 2 2 2 0 zinc-ribbon family PLATZ PF04640.14 EGG06969.1 - 1.8 9.3 9.1 0.69 10.6 1.7 2.7 2 1 1 3 3 3 0 PLATZ transcription factor LIM PF00412.22 EGG06969.1 - 4.2 7.7 10.5 12 6.2 0.1 3.3 3 1 0 3 3 3 0 LIM domain TRP_2 PF08344.11 EGG06969.1 - 7.2 6.9 8.0 11 6.4 0.0 3.0 3 1 0 3 3 3 0 Transient receptor ion channel II Actin PF00022.19 EGG06970.1 - 1e-115 386.7 0.0 4.7e-115 384.4 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGG06970.1 - 0.11 11.3 0.0 0.41 9.4 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein DUF1741 PF08427.10 EGG06972.1 - 0.052 13.2 0.1 0.052 13.2 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1741) Presenilin PF01080.17 EGG06972.1 - 0.2 10.4 1.1 0.47 9.2 1.1 1.6 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EGG06972.1 - 1.1 7.8 7.7 1.7 7.3 7.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ASD2 PF08687.11 EGG06972.1 - 2.3 7.7 6.1 0.81 9.2 3.1 1.7 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Histone PF00125.24 EGG06973.1 - 6.1e-18 65.4 0.0 7.6e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGG06973.1 - 1.6e-06 28.3 0.0 2.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGG06973.1 - 0.00041 20.8 0.0 0.00053 20.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A NFACT-R_2 PF18297.1 EGG06973.1 - 0.016 15.4 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 NFACT protein RNA binding domain CAP_GLY PF01302.25 EGG06974.1 - 6.2e-25 87.0 0.2 1.2e-24 86.1 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EGG06974.1 - 8.6e-21 74.2 0.0 1.5e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EGG06974.1 - 2.9e-06 26.9 0.1 0.031 14.0 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin family CRM1_C PF08767.11 EGG06975.1 - 2.7e-120 401.4 0.0 1.6e-118 395.6 0.0 2.6 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 EGG06975.1 - 1.2e-38 132.5 6.4 1.7e-38 132.0 4.4 2.4 2 0 0 2 2 2 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EGG06975.1 - 4.5e-32 109.5 2.9 1.2e-31 108.1 2.9 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EGG06975.1 - 3.6e-29 100.6 2.5 8.4e-29 99.5 1.1 2.5 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EGG06975.1 - 2.7e-18 65.2 1.9 5.4e-18 64.2 1.9 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EGG06975.1 - 9.3e-15 54.3 1.1 2.8e-14 52.8 0.2 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 EGG06975.1 - 0.013 14.1 0.1 0.77 8.2 0.0 3.1 2 1 0 3 3 3 0 Adaptin N terminal region DUF3385 PF11865.8 EGG06975.1 - 0.036 14.0 0.1 0.89 9.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Nrap_D4 PF17405.2 EGG06976.1 - 1.2e-50 171.8 0.0 1.9e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 EGG06976.1 - 9.1e-35 120.0 0.1 1.9e-34 118.9 0.1 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D5 PF17406.2 EGG06976.1 - 4.7e-30 104.5 2.8 5.4e-28 97.8 2.2 2.6 2 1 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 EGG06976.1 - 4.6e-29 101.6 0.0 1.1e-28 100.3 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 EGG06976.1 - 5.9e-19 68.6 0.0 1.2e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap_D2 PF17403.2 EGG06976.1 - 4.3e-10 39.6 0.0 3.1e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain PAP_central PF04928.17 EGG06976.1 - 0.0072 15.3 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain RRM_3 PF08777.11 EGG06977.1 - 3.9e-05 23.6 0.0 0.00013 21.9 0.0 1.9 1 1 0 1 1 1 1 RNA binding motif Glyco_hydro_15 PF00723.21 EGG06978.1 - 6.5e-49 166.9 0.0 4.9e-47 160.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 gag-asp_proteas PF13975.6 EGG06980.1 - 0.0079 16.7 0.1 0.059 13.9 0.0 2.6 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 EGG06980.1 - 0.011 15.6 0.1 0.081 12.7 0.1 2.3 1 1 0 1 1 1 0 Aspartyl protease CCDC74_C PF14917.6 EGG06980.1 - 0.041 14.4 0.8 0.14 12.6 0.8 1.9 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal RVP PF00077.20 EGG06980.1 - 0.052 13.9 2.2 0.53 10.6 0.0 3.2 3 2 1 4 4 4 0 Retroviral aspartyl protease DASH_Dad4 PF08650.10 EGG06980.1 - 0.088 12.8 4.4 16 5.5 0.2 4.0 4 0 0 4 4 4 0 DASH complex subunit Dad4 Vps51 PF08700.11 EGG06980.1 - 0.18 11.9 3.9 5.3 7.2 0.4 3.1 1 1 1 3 3 3 0 Vps51/Vps67 Fez1 PF06818.15 EGG06980.1 - 0.33 11.4 7.0 3.1 8.2 0.1 2.3 1 1 1 2 2 2 0 Fez1 PhaP_Bmeg PF09602.10 EGG06980.1 - 0.69 9.8 9.4 0.1 12.5 0.8 2.5 1 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) PepSY_TM_like_2 PF16357.5 EGG06980.1 - 2.1 8.3 4.6 1.2 9.0 2.2 1.8 2 1 0 2 2 2 0 Putative PepSY_TM-like SlyX PF04102.12 EGG06980.1 - 2.5 8.8 5.2 3.9 8.2 2.0 2.6 2 0 0 2 2 2 0 SlyX DUF948 PF06103.11 EGG06980.1 - 5 7.5 6.7 1.1 9.6 0.3 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.21 EGG06981.1 - 0.033 14.3 0.9 0.08 13.1 0.9 1.6 1 0 0 1 1 1 0 bZIP transcription factor Seryl_tRNA_N PF02403.22 EGG06981.1 - 0.078 13.2 0.5 0.18 12.0 0.5 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.6 EGG06981.1 - 0.096 13.1 1.7 0.18 12.2 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DivIC PF04977.15 EGG06981.1 - 0.14 12.0 1.6 0.3 10.9 1.6 1.5 1 0 0 1 1 1 0 Septum formation initiator GrpE PF01025.19 EGG06981.1 - 0.18 11.5 1.4 0.33 10.6 1.4 1.3 1 0 0 1 1 1 0 GrpE WD40_alt PF14077.6 EGG06981.1 - 0.25 11.3 0.5 0.55 10.1 0.5 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Cas6b_C PF17262.2 EGG06983.1 - 0.021 14.9 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 Cas6b C-terminal domain Coilin_N PF15862.5 EGG06984.1 - 4.3e-05 23.3 7.6 0.0013 18.5 0.0 3.1 2 1 1 3 3 3 1 Coilin N-terminus Nop14 PF04147.12 EGG06984.1 - 7.2 4.7 36.9 0.78 7.9 27.9 2.0 2 0 0 2 2 2 0 Nop14-like family Mrr_N PF14338.6 EGG06986.1 - 0.12 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Mrr N-terminal domain PdaC PF13739.6 EGG06987.1 - 0.017 16.1 0.0 0.017 16.1 0.0 2.9 2 1 0 2 2 2 0 Deacetylase PdaC SnoaL_4 PF13577.6 EGG06988.1 - 0.03 14.5 0.0 0.059 13.5 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain DUF3139 PF11337.8 EGG06988.1 - 0.031 14.9 0.1 0.084 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Elf1 PF05129.13 EGG06989.1 - 0.22 11.6 6.9 0.64 10.1 1.6 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like PQ-loop PF04193.14 EGG06990.1 - 1.4e-18 66.4 7.6 4.3e-15 55.2 0.4 3.2 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 EGG06990.1 - 0.022 15.6 2.7 0.068 14.0 0.6 2.3 2 0 0 2 2 2 0 ER lumen protein retaining receptor MIP PF00230.20 EGG06992.1 - 3.2e-15 56.5 9.7 6.8e-11 42.3 5.9 3.2 1 1 1 2 2 2 2 Major intrinsic protein V-ATPase_G PF03179.15 EGG06993.1 - 8.7e-35 119.4 14.0 9.9e-35 119.3 14.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit RRF PF01765.19 EGG06993.1 - 0.014 15.3 8.2 0.022 14.7 8.2 1.2 1 0 0 1 1 1 0 Ribosome recycling factor ATP-synt_B PF00430.18 EGG06993.1 - 0.03 14.4 12.9 0.03 14.4 12.9 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 EGG06993.1 - 0.057 13.8 13.2 0.087 13.3 13.2 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit SOAR PF16533.5 EGG06993.1 - 0.1 12.6 6.5 0.18 11.8 6.5 1.5 1 1 0 1 1 1 0 STIM1 Orai1-activating region DUF4168 PF13767.6 EGG06993.1 - 0.12 13.6 8.9 0.65 11.2 7.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) 4HB_MCP_1 PF12729.7 EGG06993.1 - 0.24 10.9 4.6 0.17 11.4 1.5 1.8 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction ATP11 PF06644.11 EGG06993.1 - 0.32 10.7 5.6 0.38 10.5 5.6 1.0 1 0 0 1 1 1 0 ATP11 protein TarH PF02203.15 EGG06993.1 - 0.82 9.6 3.9 3.2 7.6 1.0 2.2 1 1 1 2 2 2 0 Tar ligand binding domain homologue vATP-synt_E PF01991.18 EGG06993.1 - 4.8 6.5 16.8 6.3 6.1 8.0 2.1 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit TFIIF_alpha PF05793.12 EGG06994.1 - 8.6 4.8 13.2 16 4.0 13.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NUDIX PF00293.28 EGG06995.1 - 1.5e-10 41.2 0.5 1.9e-10 40.9 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain HMG_box PF00505.19 EGG06997.1 - 0.0011 19.3 0.1 0.0025 18.2 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box TPP_enzyme_N PF02776.18 EGG07000.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain CDP-OH_P_transf PF01066.21 EGG07002.1 - 3.1e-12 47.1 0.5 7.2e-12 45.9 0.5 1.6 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase HD PF01966.22 EGG07003.1 - 7.8e-06 26.1 0.4 2.9e-05 24.3 0.2 1.9 2 0 0 2 2 2 1 HD domain HD_4 PF13328.6 EGG07003.1 - 0.066 13.0 0.1 0.17 11.6 0.1 1.6 2 0 0 2 2 2 0 HD domain PX PF00787.24 EGG07004.1 - 2.1e-20 72.8 0.0 4.6e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF3215 PF11503.8 EGG07004.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) Ribosomal_L16 PF00252.18 EGG07005.1 - 3.6e-45 153.2 0.0 4.4e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e NCBP3 PF10309.9 EGG07006.1 - 8.7e-09 35.1 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 FoP_duplication PF13865.6 EGG07006.1 - 0.02 15.4 2.3 0.02 15.4 2.3 3.6 2 1 1 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 Methyltransf_23 PF13489.6 EGG07007.1 - 2.3e-22 79.6 0.0 3.5e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG07007.1 - 2.2e-17 63.5 0.1 1.1e-16 61.2 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG07007.1 - 6.8e-15 55.2 0.1 4.4e-14 52.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG07007.1 - 2.7e-14 53.7 0.1 7.3e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG07007.1 - 4.5e-14 52.9 0.2 2.8e-12 47.2 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGG07007.1 - 2.9e-06 26.9 0.0 5.7e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EGG07007.1 - 1.7e-05 24.3 0.0 0.00035 20.0 0.0 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 EGG07007.1 - 9e-05 22.0 0.0 0.00037 20.0 0.0 1.8 1 1 1 2 2 2 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 EGG07007.1 - 0.00014 20.9 0.1 0.0005 19.1 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 EGG07007.1 - 0.00014 22.0 0.0 0.0002 21.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EGG07007.1 - 0.00057 19.3 0.0 0.0014 18.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EGG07007.1 - 0.00092 19.2 0.6 0.0016 18.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGG07007.1 - 0.0023 17.5 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EGG07007.1 - 0.0035 17.0 0.0 1.1 8.9 0.0 2.1 1 1 1 2 2 2 2 Nodulation protein S (NodS) DREV PF05219.12 EGG07007.1 - 0.053 12.6 0.0 0.26 10.3 0.0 1.9 1 1 0 1 1 1 0 DREV methyltransferase TPMT PF05724.11 EGG07007.1 - 0.065 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 EGG07007.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EGG07007.1 - 0.21 11.1 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Peptidase_C13 PF01650.18 EGG07008.1 - 1.3e-43 149.4 0.1 1.6e-43 149.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 EGG07008.1 - 0.063 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute Ribosom_S12_S23 PF00164.25 EGG07009.1 - 1.3e-40 137.6 0.4 1.6e-40 137.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ABC_tran PF00005.27 EGG07012.1 - 8.3e-24 84.7 0.0 6.6e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 EGG07012.1 - 5.3e-13 48.5 6.6 1e-12 47.6 6.6 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 EGG07012.1 - 3e-11 43.2 1.3 0.00091 18.7 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGG07012.1 - 6.3e-10 39.3 0.2 0.026 14.3 0.0 3.3 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGG07012.1 - 0.0036 17.1 0.3 0.38 10.4 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 EGG07012.1 - 0.0053 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 EGG07012.1 - 0.028 14.8 0.0 0.064 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EGG07012.1 - 0.041 14.4 0.4 0.11 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGG07012.1 - 0.042 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGG07012.1 - 0.046 14.0 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 EGG07012.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGG07012.1 - 0.12 12.8 0.0 0.47 10.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 EGG07012.1 - 0.13 12.3 0.0 0.63 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 EGG07012.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Glyco_hydro_17 PF00332.18 EGG07014.1 - 1.6e-07 31.3 0.7 3e-07 30.3 0.2 1.8 3 0 0 3 3 3 1 Glycosyl hydrolases family 17 NAD_binding_10 PF13460.6 EGG07014.1 - 0.16 11.8 0.1 0.37 10.7 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding bacHORMA_2 PF18173.1 EGG07015.1 - 0.0017 18.2 0.0 0.0018 18.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial HORMA domain 2 DUF1264 PF06884.11 EGG07017.1 - 2.3e-21 76.2 1.4 2.4e-21 76.1 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF1264 PF06884.11 EGG07018.1 - 4.3e-17 62.2 0.1 7.9e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) AFT PF08731.11 EGG07020.1 - 0.0021 18.4 0.1 0.0021 18.4 0.1 3.4 4 0 0 4 4 4 1 Transcription factor AFT CxC1 PF18802.1 EGG07021.1 - 1.3e-27 95.9 0.1 2.1e-27 95.3 0.1 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG07021.1 - 1.7e-05 24.9 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG07021.1 - 0.078 12.8 0.0 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases DDE_1 PF03184.19 EGG07023.1 - 0.00067 19.3 0.4 0.0011 18.7 0.4 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Trimer_CC PF08954.11 EGG07023.1 - 0.21 11.2 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Trimerisation motif IPP-2 PF04979.14 EGG07026.1 - 2.9e-18 66.9 4.2 5.1e-18 66.1 4.2 1.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) FAM176 PF14851.6 EGG07026.1 - 0.09 12.4 5.8 0.15 11.8 5.8 1.2 1 0 0 1 1 1 0 FAM176 family IPP-2 PF04979.14 EGG07027.1 - 7.4e-16 59.1 4.3 9.4e-16 58.8 4.3 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) FAM176 PF14851.6 EGG07027.1 - 0.019 14.6 4.7 0.027 14.2 4.7 1.2 1 0 0 1 1 1 0 FAM176 family ABC_tran PF00005.27 EGG07028.1 - 3.1e-51 173.5 0.4 7.5e-29 101.0 0.1 3.0 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 EGG07028.1 - 2.4e-25 89.7 11.4 3e-24 86.1 5.1 4.1 5 0 0 5 5 4 2 ABC transporter transmembrane region T2SSE PF00437.20 EGG07028.1 - 5.9e-09 35.4 0.1 0.00019 20.6 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 EGG07028.1 - 1e-07 31.6 1.7 0.00083 19.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EGG07028.1 - 3.7e-07 29.8 6.7 0.11 11.9 2.6 4.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EGG07028.1 - 4.7e-07 30.1 0.2 0.0039 17.3 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_16 PF13191.6 EGG07028.1 - 1.9e-06 28.4 0.1 0.06 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EGG07028.1 - 3.9e-05 23.8 0.1 0.18 11.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 EGG07028.1 - 8.2e-05 23.2 4.9 0.0013 19.2 0.1 2.6 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 EGG07028.1 - 9.1e-05 22.8 1.7 0.36 11.1 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EGG07028.1 - 0.00017 21.5 0.1 0.18 11.6 0.1 3.7 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EGG07028.1 - 0.00026 20.8 0.6 0.78 9.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EGG07028.1 - 0.0007 19.5 0.1 0.55 10.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EGG07028.1 - 0.00093 18.8 0.9 0.47 10.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGG07028.1 - 0.0011 19.0 3.3 0.27 11.3 0.1 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EGG07028.1 - 0.0012 18.3 1.5 0.79 9.0 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 EGG07028.1 - 0.0019 17.2 0.3 0.34 9.8 0.1 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 EGG07028.1 - 0.0021 17.6 0.5 1.2 8.6 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region NACHT PF05729.12 EGG07028.1 - 0.0022 17.9 4.5 0.65 9.9 0.1 3.4 3 1 0 3 3 3 2 NACHT domain AAA_24 PF13479.6 EGG07028.1 - 0.0035 17.1 0.1 0.55 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 EGG07028.1 - 0.0042 16.9 0.6 2.1 8.1 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EGG07028.1 - 0.0043 17.1 0.5 1.3 9.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family NB-ARC PF00931.22 EGG07028.1 - 0.0054 15.9 0.1 1.1 8.4 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.14 EGG07028.1 - 0.0065 16.5 2.9 1.3 9.0 0.1 4.0 5 0 0 5 5 3 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGG07028.1 - 0.0074 16.0 0.1 2.3 7.9 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EGG07028.1 - 0.0074 16.7 0.0 4 7.9 0.0 2.8 2 0 0 2 2 2 1 RNA helicase cobW PF02492.19 EGG07028.1 - 0.0076 15.8 0.8 1.2 8.7 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 EGG07028.1 - 0.0093 15.2 0.3 0.79 8.9 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 EGG07028.1 - 0.018 15.6 0.1 11 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGG07028.1 - 0.024 13.9 0.8 7 5.9 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin SRP54 PF00448.22 EGG07028.1 - 0.024 14.3 0.3 0.3 10.7 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATPase PF06745.13 EGG07028.1 - 0.046 13.1 0.4 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 KaiC APS_kinase PF01583.20 EGG07028.1 - 0.083 12.8 0.4 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA PF00004.29 EGG07028.1 - 0.085 13.3 1.7 17 5.9 0.0 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EGG07028.1 - 0.1 12.5 5.3 2.6 7.9 0.1 3.1 3 0 0 3 3 3 0 NTPase PhoH PF02562.16 EGG07028.1 - 0.13 11.7 0.2 14 5.1 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 EGG07028.1 - 0.14 11.9 0.6 33 4.2 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase AIG1 PF04548.16 EGG07028.1 - 3.7 6.8 4.2 30 3.8 0.2 3.1 3 0 0 3 3 3 0 AIG1 family HEAT PF02985.22 EGG07031.1 - 6.3e-05 22.9 0.3 0.78 10.2 0.0 3.1 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 EGG07031.1 - 0.00019 21.7 0.4 0.00051 20.4 0.4 1.8 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 EGG07031.1 - 0.058 13.9 0.6 2.4 8.8 0.2 2.6 1 1 1 2 2 2 0 HEAT-like repeat DUF3361 PF11841.8 EGG07031.1 - 0.064 13.2 0.1 0.073 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) PYRIN PF02758.16 EGG07031.1 - 0.093 12.9 0.3 0.15 12.2 0.3 1.5 1 1 0 1 1 1 0 PAAD/DAPIN/Pyrin domain DUF3767 PF12597.8 EGG07032.1 - 6e-07 29.2 0.0 9.6e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) ATP-synt_C PF00137.21 EGG07033.1 - 1.5e-29 102.1 37.1 2.2e-17 63.2 15.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C IncD PF17628.2 EGG07033.1 - 0.032 14.0 3.0 0.052 13.3 3.0 1.4 1 0 0 1 1 1 0 Inclusion membrane protein D ATP-synt_J PF04911.12 EGG07033.1 - 1.9 8.1 5.6 8.4 6.1 0.9 2.5 2 0 0 2 2 2 0 ATP synthase j chain DUF2797 PF10977.8 EGG07034.1 - 0.64 9.9 6.6 0.84 9.5 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) LRR_6 PF13516.6 EGG07036.1 - 0.13 12.4 0.1 64 4.0 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat ATP-synt_E PF05680.12 EGG07037.1 - 1 9.7 6.1 0.29 11.5 1.0 2.4 2 1 0 2 2 2 0 ATP synthase E chain ATP-synt_E PF05680.12 EGG07038.1 - 1 9.7 6.1 0.29 11.5 1.0 2.4 2 1 0 2 2 2 0 ATP synthase E chain COX6B PF02297.17 EGG07040.1 - 1.2e-16 60.7 9.3 1.6e-16 60.3 9.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb VanZ PF04892.12 EGG07041.1 - 1.7e-06 28.7 1.9 2.7e-06 28.0 1.9 1.4 1 0 0 1 1 1 1 VanZ like family CxC5 PF18718.1 EGG07044.1 - 7.1e-32 109.9 7.9 1.2e-31 109.2 7.9 1.4 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases zf-UBP PF02148.19 EGG07044.1 - 2.1 8.7 6.2 6.8 7.1 5.8 2.1 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Dioxygenase_C PF00775.21 EGG07047.1 - 1.2e-08 34.6 0.0 7.7e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 Dioxygenase Squash PF00299.18 EGG07048.1 - 0.012 15.6 0.8 0.037 14.1 0.8 1.8 1 0 0 1 1 1 0 Squash family serine protease inhibitor FOLN PF09289.10 EGG07048.1 - 0.093 12.9 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Sgf11_N PF18519.1 EGG07048.1 - 0.19 11.3 0.1 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain Pkinase PF00069.25 EGG07050.1 - 6.7e-63 212.5 0.0 1.6e-62 211.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG07050.1 - 2e-35 122.4 0.0 3.3e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EGG07050.1 - 5.3e-23 80.9 10.5 1.2e-11 44.6 3.5 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 EGG07050.1 - 5.8e-22 77.3 22.9 5.6e-12 45.4 8.9 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EGG07050.1 - 3.7e-11 43.5 0.2 3.7e-11 43.5 0.2 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 EGG07050.1 - 2.1e-08 34.4 0.1 4.1e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EGG07050.1 - 0.017 14.4 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EGG07050.1 - 0.074 12.0 0.1 0.15 10.9 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Crp PF00325.20 EGG07050.1 - 0.15 11.8 0.0 0.41 10.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family zf-RING_9 PF13901.6 EGG07050.1 - 0.62 10.0 18.8 1.9 8.4 7.0 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon C1_2 PF03107.16 EGG07050.1 - 1 9.8 16.4 2 8.8 6.3 2.5 2 0 0 2 2 2 0 C1 domain DNA_pol_E_B PF04042.16 EGG07051.1 - 2.3e-29 102.3 0.1 3.3e-29 101.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 EGG07051.1 - 1.5e-20 74.2 0.1 2.3e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal SnoaL_2 PF12680.7 EGG07052.1 - 0.0049 17.5 0.0 0.0067 17.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain HA2 PF04408.23 EGG07054.1 - 3.9e-23 81.8 0.5 1.2e-22 80.2 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGG07054.1 - 3.9e-18 65.6 0.1 8.4e-18 64.5 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGG07054.1 - 3.4e-11 43.4 0.0 1.1e-10 41.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGG07054.1 - 6.3e-07 29.8 0.0 2e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EGG07054.1 - 1.7e-06 27.9 0.1 5.1e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EGG07054.1 - 0.0028 18.0 0.0 0.0059 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG07054.1 - 0.0049 16.6 0.1 0.0093 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGG07054.1 - 0.0063 15.6 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 EGG07054.1 - 0.0095 16.5 0.1 0.0095 16.5 0.1 3.4 3 1 0 3 3 3 1 AAA domain ATPase PF06745.13 EGG07054.1 - 0.012 14.9 0.1 0.07 12.5 0.0 2.1 2 0 0 2 2 2 0 KaiC FtsK_SpoIIIE PF01580.18 EGG07054.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2075 PF09848.9 EGG07054.1 - 0.064 12.5 0.0 0.16 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EGG07054.1 - 0.078 12.4 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 EGG07054.1 - 0.4 11.2 1.6 2.2 8.8 0.0 3.0 4 0 0 4 4 3 0 ABC transporter DNA_methylase PF00145.17 EGG07057.1 - 3.2e-40 138.5 0.0 4.7e-39 134.7 0.0 2.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Glyco_hydro_7 PF00840.20 EGG07059.1 - 3.4e-158 526.9 1.3 3.9e-158 526.7 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DP-EP PF08985.11 EGG07059.1 - 0.19 11.9 0.2 0.66 10.2 0.1 2.1 2 0 0 2 2 2 0 DP-EP family CxC6 PF18721.1 EGG07061.1 - 4.5e-21 74.9 3.4 4.5e-21 74.9 3.4 2.5 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases Albumin_I_a PF16720.5 EGG07061.1 - 2 8.4 4.8 23 5.0 0.0 3.4 3 0 0 3 3 3 0 Albumin I chain a Pkinase PF00069.25 EGG07064.1 - 2.1e-65 220.7 0.0 2.4e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG07064.1 - 1e-25 90.5 0.0 1.4e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG07064.1 - 3e-05 23.5 0.1 0.03 13.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 EGG07064.1 - 7.6e-05 21.8 0.3 0.00012 21.2 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGG07064.1 - 0.00055 19.6 0.1 0.00082 19.0 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EGG07064.1 - 0.089 11.6 0.4 0.2 10.4 0.1 1.6 1 1 1 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EGG07064.1 - 0.16 11.3 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4834 PF16118.5 EGG07065.1 - 1.2 10.2 5.4 25 5.9 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) DUF3169 PF11368.8 EGG07065.1 - 2 7.9 7.5 0.29 10.6 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) TFIID-18kDa PF02269.16 EGG07066.1 - 2.9e-14 52.8 0.3 1e-11 44.7 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.15 EGG07066.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CPSase_L_D2 PF02786.17 EGG07067.1 - 2.5e-78 262.4 0.5 4.4e-78 261.6 0.5 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EGG07067.1 - 3.8e-71 239.0 0.0 7.3e-71 238.0 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EGG07067.1 - 3.2e-40 137.1 0.1 7.2e-40 136.0 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGG07067.1 - 4.7e-31 107.1 0.0 1.7e-30 105.3 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EGG07067.1 - 4.6e-27 95.2 0.0 1.2e-26 93.8 0.0 1.7 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EGG07067.1 - 2.1e-16 59.5 3.8 8.5e-16 57.6 3.5 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGG07067.1 - 1.6e-11 44.1 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EGG07067.1 - 2.7e-09 36.7 1.0 0.00013 21.7 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 EGG07067.1 - 6e-07 29.2 0.1 1.4e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGG07067.1 - 1.9e-05 24.8 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EGG07067.1 - 0.00015 22.5 0.4 0.82 10.4 0.1 2.9 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_4 PF13535.6 EGG07067.1 - 0.0002 21.0 0.0 0.00044 19.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EGG07067.1 - 0.0016 18.3 0.1 0.0035 17.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.11 EGG07067.1 - 0.0022 17.5 0.2 0.0043 16.5 0.2 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_D23 PF16576.5 EGG07067.1 - 0.0047 16.2 0.4 0.066 12.4 0.1 2.5 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 EGG07067.1 - 0.035 13.4 0.0 0.087 12.0 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 EGG07067.1 - 0.045 13.6 0.6 0.2 11.5 0.3 2.2 1 1 1 2 2 2 0 Glycine cleavage H-protein ATPgrasp_Ter PF15632.6 EGG07067.1 - 0.14 12.0 0.1 0.44 10.3 0.1 1.8 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon LCM PF04072.14 EGG07068.1 - 1.2e-12 48.1 0.0 2.6e-12 47.1 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Methyltransf_23 PF13489.6 EGG07068.1 - 0.0054 16.6 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain SRP54 PF00448.22 EGG07070.1 - 1.6e-47 161.7 0.1 2.8e-47 160.9 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 EGG07070.1 - 1.5e-33 117.0 4.6 1.6e-32 113.6 4.6 2.0 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal MeaB PF03308.16 EGG07070.1 - 1.2e-08 34.3 0.0 2.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54_N PF02881.19 EGG07070.1 - 5.6e-06 26.5 0.0 1.9e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 EGG07070.1 - 0.00083 19.4 0.0 0.017 15.2 0.0 2.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 EGG07070.1 - 0.0018 18.6 0.5 0.075 13.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGG07070.1 - 0.0049 16.6 1.6 0.0056 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EGG07070.1 - 0.0068 15.6 0.4 0.12 11.5 0.0 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_16 PF13191.6 EGG07070.1 - 0.012 16.0 0.3 0.069 13.5 0.0 2.4 2 1 1 3 3 3 0 AAA ATPase domain SMC_N PF02463.19 EGG07070.1 - 0.03 13.7 0.6 6.8 6.1 0.4 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EGG07070.1 - 0.032 13.9 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 EGG07070.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NPV_P10 PF05531.12 EGG07071.1 - 0.0029 18.0 1.4 0.0029 18.0 1.4 2.3 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF848 PF05852.11 EGG07071.1 - 0.012 15.7 3.0 0.012 15.7 3.0 2.3 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2730 PF10805.8 EGG07071.1 - 0.027 14.5 1.1 0.084 13.0 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) BLOC1_2 PF10046.9 EGG07071.1 - 0.072 13.4 0.3 0.072 13.4 0.3 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 EGG07071.1 - 0.08 12.5 2.5 0.17 11.5 2.5 1.5 1 0 0 1 1 1 0 fzo-like conserved region DUF4254 PF14063.6 EGG07071.1 - 0.12 12.2 3.5 0.25 11.1 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) CHDCT2 PF08074.11 EGG07071.1 - 0.39 10.9 6.7 0.044 13.9 1.4 2.1 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain LPP PF04728.13 EGG07071.1 - 1 9.8 5.6 12 6.4 0.1 3.0 2 1 1 3 3 2 0 Lipoprotein leucine-zipper HsbA PF12296.8 EGG07071.1 - 1.6 9.2 6.9 1.2 9.6 0.1 2.8 3 0 0 3 3 3 0 Hydrophobic surface binding protein A FlaC_arch PF05377.11 EGG07071.1 - 1.6 9.2 7.8 16 5.9 0.4 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EGG07071.1 - 5.2 7.1 7.0 1.5 8.9 1.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 EGG07071.1 - 5.7 7.6 9.9 14 6.3 0.5 2.7 1 1 1 2 2 2 0 SlyX CCDC-167 PF15188.6 EGG07072.1 - 0.0059 16.9 3.7 0.0078 16.5 3.0 1.6 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 CENP-H PF05837.12 EGG07072.1 - 0.0089 16.4 1.8 0.014 15.8 1.8 1.2 1 0 0 1 1 1 1 Centromere protein H (CENP-H) DUF2605 PF10792.9 EGG07072.1 - 0.017 15.0 1.6 0.051 13.5 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) YkyA PF10368.9 EGG07072.1 - 0.023 14.4 5.3 0.032 13.9 5.3 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Ntox28 PF15605.6 EGG07072.1 - 0.065 13.5 0.6 0.13 12.5 0.5 1.6 1 1 0 1 1 1 0 Bacterial toxin 28 RRP36 PF06102.12 EGG07072.1 - 0.073 13.0 3.4 0.12 12.3 3.4 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF745 PF05335.13 EGG07072.1 - 0.21 11.3 1.5 3.8 7.2 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF4678 PF15727.5 EGG07073.1 - 0.0034 16.7 0.5 0.0077 15.5 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4678) NAM-associated PF14303.6 EGG07075.1 - 8.2e-09 36.4 0.4 1.7e-08 35.4 0.4 1.5 1 1 0 1 1 1 1 No apical meristem-associated C-terminal domain SMC_Nse1 PF07574.13 EGG07078.1 - 4e-20 72.6 0.3 1.6e-17 64.1 0.0 2.9 2 1 0 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EGG07078.1 - 2.9e-07 30.7 10.1 2.9e-07 30.7 10.1 1.6 2 0 0 2 2 1 1 RING-like domain Rtf2 PF04641.12 EGG07078.1 - 0.066 12.6 7.2 0.1 12.0 7.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-HC5HC2H_2 PF13832.6 EGG07078.1 - 0.11 12.6 4.1 0.43 10.8 4.1 1.9 1 1 0 1 1 1 0 PHD-zinc-finger like domain RNA_pol_Rpc4 PF05132.14 EGG07078.1 - 0.13 12.7 3.7 0.19 12.2 3.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 EGG07078.1 - 0.34 11.1 4.4 0.51 10.5 4.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 EGG07078.1 - 0.5 8.6 10.3 0.66 8.2 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 EGG07078.1 - 0.51 9.3 10.5 0.83 8.6 10.5 1.3 1 0 0 1 1 1 0 Paf1 C1_2 PF03107.16 EGG07078.1 - 0.59 10.5 5.7 0.11 12.9 1.0 2.1 2 0 0 2 2 2 0 C1 domain Raftlin PF15250.6 EGG07078.1 - 1.2 7.8 7.3 1.7 7.3 7.3 1.1 1 0 0 1 1 1 0 Raftlin zf-RING_2 PF13639.6 EGG07078.1 - 1.9 8.9 8.5 3.7 8.0 8.5 1.5 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H PF13771.6 EGG07078.1 - 4.3 7.6 9.1 27 5.1 9.1 2.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain Apt1 PF10351.9 EGG07078.1 - 5.9 5.6 9.0 8.5 5.1 9.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Coilin_N PF15862.5 EGG07078.1 - 8.5 6.2 10.6 16 5.3 10.6 1.3 1 0 0 1 1 1 0 Coilin N-terminus PPR PF01535.20 EGG07079.1 - 5.8e-22 76.3 7.6 0.16 12.3 0.2 10.4 10 0 0 10 10 10 6 PPR repeat PPR_2 PF13041.6 EGG07079.1 - 1.2e-18 67.0 0.1 0.0001 22.4 0.1 8.8 10 2 1 11 11 11 4 PPR repeat family PPR_3 PF13812.6 EGG07079.1 - 2.3e-16 59.6 0.0 4e-06 26.8 0.0 5.6 4 1 1 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGG07079.1 - 9.9e-09 34.8 0.0 0.86 9.4 0.0 6.9 8 0 0 8 8 8 3 PPR repeat TPR_19 PF14559.6 EGG07079.1 - 0.0039 17.7 5.8 1.5 9.4 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat SPOB_a PF14689.6 EGG07079.1 - 0.0074 16.0 0.1 0.065 13.0 0.0 2.6 2 0 0 2 2 2 1 Sensor_kinase_SpoOB-type, alpha-helical domain Macoilin PF09726.9 EGG07079.1 - 0.53 8.8 13.6 0.97 7.9 13.6 1.4 1 0 0 1 1 1 0 Macoilin family CNDH2_M PF16869.5 EGG07085.1 - 0.37 11.5 4.5 0.41 11.3 3.6 1.6 1 1 1 2 2 2 0 PF16858 Membralin PF09746.9 EGG07085.1 - 10 5.1 7.1 11 5.0 7.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein LRR_4 PF12799.7 EGG07086.1 - 0.47 10.9 12.8 7.1 7.2 2.5 5.3 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) TFIIF_alpha PF05793.12 EGG07088.1 - 1.4 7.4 7.1 1.9 7.0 7.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GFA PF04828.14 EGG07089.1 - 4.4e-25 87.9 0.2 5.8e-25 87.5 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF1990 PF09348.10 EGG07089.1 - 0.067 13.2 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) Nudix_N_2 PF14803.6 EGG07089.1 - 0.18 11.7 4.3 0.51 10.3 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal Elf1 PF05129.13 EGG07089.1 - 0.44 10.6 2.9 7.7 6.6 0.3 2.4 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zf-NADH-PPase PF09297.11 EGG07089.1 - 0.7 9.6 0.1 0.7 9.6 0.1 2.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain FAD_binding_4 PF01565.23 EGG07090.1 - 3.6e-20 72.1 3.0 7.1e-20 71.2 2.5 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EGG07090.1 - 9e-09 35.3 0.0 1.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.19 EGG07090.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain DUF3959 PF13105.6 EGG07092.1 - 0.75 9.3 3.2 1.5 8.3 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) E7 PF00527.18 EGG07092.1 - 4 7.7 7.2 2.9 8.2 1.0 2.6 2 0 0 2 2 2 0 E7 protein, Early protein PBP1_TM PF14812.6 EGG07092.1 - 6.9 7.1 6.8 37 4.8 0.5 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Lyase_8_C PF02884.17 EGG07093.1 - 0.024 15.1 0.1 4.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain SMK-1 PF04802.15 EGG07094.1 - 6e-72 241.5 0.2 1.8e-71 239.9 0.1 1.8 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Complex1_LYR PF05347.15 EGG07095.1 - 0.028 14.5 0.7 0.05 13.6 0.4 1.5 2 0 0 2 2 2 0 Complex 1 protein (LYR family) DUF1156 PF06634.12 EGG07095.1 - 0.13 12.3 0.1 0.39 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1156) DUF3848 PF12959.7 EGG07096.1 - 0.0026 17.8 0.8 0.054 13.6 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3848) APG17 PF04108.12 EGG07096.1 - 0.0034 16.6 8.0 0.0034 16.6 8.0 2.0 2 0 0 2 2 2 1 Autophagy protein Apg17 2OG-FeII_Oxy_2 PF13532.6 EGG07097.1 - 0.08 13.1 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Gln-synt_C PF00120.24 EGG07098.1 - 9.4e-79 264.9 0.0 1.2e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain ADH_N_2 PF16884.5 EGG07099.1 - 1.1e-17 63.8 0.0 2.2e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EGG07099.1 - 8.3e-14 51.7 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1624 PF07786.12 EGG07100.1 - 1.2e-06 28.2 0.1 0.00017 21.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1624) DUF5009 PF16401.5 EGG07100.1 - 2.2e-05 24.1 0.2 5.9e-05 22.7 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5009) OpgC_C PF10129.9 EGG07100.1 - 0.013 14.3 0.4 0.12 11.2 0.2 2.1 2 0 0 2 2 2 0 OpgC protein Cas1_AcylT PF07779.12 EGG07100.1 - 0.1 11.5 0.2 0.13 11.2 0.2 1.1 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p Ferritin_2 PF13668.6 EGG07101.1 - 2.1e-46 157.5 3.1 2.9e-46 157.0 3.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.6 EGG07102.1 - 1.9e-45 154.4 1.0 2.6e-45 154.0 1.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain KbaA PF14089.6 EGG07106.1 - 0.025 14.4 1.9 0.049 13.5 1.9 1.4 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation Glyco_hydro_cc PF11790.8 EGG07107.1 - 0.023 14.2 0.2 5.8 6.4 0.0 2.7 2 1 0 2 2 2 0 Glycosyl hydrolase catalytic core Cdc13_OB4_dimer PF18233.1 EGG07107.1 - 0.21 11.8 0.0 0.39 10.9 0.0 1.3 1 0 0 1 1 1 0 Cdc13 OB4 dimerization domain RPAP1_C PF08620.10 EGG07109.1 - 0.14 12.3 0.0 0.65 10.1 0.1 2.1 2 0 0 2 2 2 0 RPAP1-like, C-terminal TACC_C PF05010.14 EGG07109.1 - 0.2 11.4 3.9 0.43 10.3 3.1 1.9 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal MRP-L46 PF11788.8 EGG07111.1 - 1.6e-12 48.2 1.0 3e-12 47.3 1.0 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 EGG07111.1 - 1.8e-10 41.0 0.0 3.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Sa_NUDIX PF18167.1 EGG07111.1 - 0.047 13.5 0.1 1.5 8.6 0.0 2.4 1 1 1 2 2 2 0 SMODS-associated NUDIX domain ArsR PF09824.9 EGG07111.1 - 0.11 12.0 0.2 2.4 7.8 0.1 2.3 2 0 0 2 2 2 0 ArsR transcriptional regulator AhpC-TSA_2 PF13911.6 EGG07113.1 - 8.3e-12 45.2 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGG07113.1 - 0.00036 20.4 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Abhydrolase_2 PF02230.16 EGG07115.1 - 8.7e-10 38.8 0.0 1.5e-08 34.8 0.2 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_2 PF02230.16 EGG07116.1 - 4e-08 33.3 0.0 2e-07 31.0 0.0 1.8 1 1 0 2 2 2 1 Phospholipase/Carboxylesterase Ribosomal_S6 PF01250.17 EGG07117.1 - 3.3e-19 68.9 0.0 4.6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 DUF5499 PF17603.2 EGG07117.1 - 0.047 14.3 0.0 0.069 13.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5499) PMT PF02366.18 EGG07118.1 - 2.7e-76 256.4 17.5 2.7e-76 256.4 17.5 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGG07118.1 - 1.7e-53 181.2 16.0 1.7e-53 181.2 16.0 1.8 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGG07118.1 - 9.8e-30 103.8 0.2 1.5e-29 103.2 0.2 1.1 1 0 0 1 1 1 1 MIR domain Imm12 PF15560.6 EGG07118.1 - 0.16 11.9 0.2 0.32 10.9 0.2 1.4 1 0 0 1 1 1 0 Immunity protein 12 PCI PF01399.27 EGG07119.1 - 2.3e-08 34.5 0.0 1.1e-07 32.4 0.0 2.2 2 0 0 2 2 2 1 PCI domain DUF3294 PF07957.11 EGG07119.1 - 0.02 14.6 0.1 0.043 13.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3294) NADH-UOR_E PF16514.5 EGG07123.1 - 0.2 12.0 1.3 0.67 10.3 1.3 1.9 1 0 0 1 1 1 0 putative NADH-ubiquinone oxidoreductase chain E IL2 PF00715.17 EGG07123.1 - 0.24 11.3 4.2 0.23 11.4 1.4 2.4 3 0 0 3 3 3 0 Interleukin 2 SF1-HH PF16275.5 EGG07123.1 - 0.62 10.4 4.0 0.25 11.7 0.7 2.1 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain PGAP1 PF07819.13 EGG07125.1 - 0.0017 18.1 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EGG07125.1 - 0.0021 17.6 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGG07125.1 - 0.0022 17.9 0.0 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase ATP-synt PF00231.19 EGG07126.1 - 6.5e-72 242.6 4.8 7.4e-72 242.4 4.8 1.0 1 0 0 1 1 1 1 ATP synthase RNA_Me_trans PF04252.13 EGG07126.1 - 0.087 12.4 0.0 5.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Predicted SAM-dependent RNA methyltransferase Peptidase_S8 PF00082.22 EGG07127.1 - 1.5e-42 145.9 0.6 2.6e-42 145.1 0.6 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EGG07127.1 - 4.3e-06 27.4 0.0 1.2e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 EGG07127.1 - 9.9e-05 22.3 0.0 0.00034 20.6 0.0 1.9 2 0 0 2 2 2 1 PA domain MutS_I PF01624.20 EGG07128.1 - 1.6e-13 50.9 0.0 1.7e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 MutS domain I MutS_V PF00488.21 EGG07129.1 - 5.9e-32 111.2 0.0 1.2e-31 110.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGG07129.1 - 0.00077 19.7 0.2 0.0015 18.8 0.2 1.5 1 0 0 1 1 1 1 MutS domain III AAA_27 PF13514.6 EGG07129.1 - 0.012 15.2 0.0 0.036 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGG07129.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGG07129.1 - 0.15 12.5 0.9 0.93 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Spc24 PF08286.11 EGG07130.1 - 0.00011 22.4 1.2 0.017 15.4 0.0 2.3 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Spc7 PF08317.11 EGG07130.1 - 0.00066 18.7 7.8 0.00092 18.2 7.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein APG6_N PF17675.1 EGG07130.1 - 0.004 17.7 10.6 0.0064 17.0 10.6 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 EGG07130.1 - 0.025 14.2 1.2 0.031 13.9 1.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2968 PF11180.8 EGG07130.1 - 0.033 13.8 6.8 0.048 13.3 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF713 PF05218.14 EGG07130.1 - 0.041 13.6 1.8 0.076 12.7 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF713) Macoilin PF09726.9 EGG07130.1 - 0.21 10.1 5.6 0.25 9.9 5.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF883 PF05957.13 EGG07130.1 - 0.58 10.8 3.2 1.5 9.4 0.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) UPF0242 PF06785.11 EGG07130.1 - 0.86 9.7 6.7 1.4 9.0 6.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 EGG07130.1 - 1.1 9.5 4.7 2.7 8.2 4.4 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 EGG07130.1 - 2.2 8.1 9.0 9.2 6.1 0.8 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF2951 PF11166.8 EGG07130.1 - 2.6 8.3 5.3 21 5.4 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) CxC1 PF18802.1 EGG07133.1 - 0.00073 19.7 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases DDE_Tnp_1 PF01609.21 EGG07134.1 - 0.075 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Transposase DDE domain Egh16-like PF11327.8 EGG07136.1 - 3.7e-25 89.4 0.2 5.3e-25 88.9 0.2 1.2 1 0 0 1 1 1 1 Egh16-like virulence factor Cid2 PF09774.9 EGG07137.1 - 0.048 14.1 1.7 0.066 13.6 1.7 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 LIN37 PF15306.6 EGG07137.1 - 0.18 12.0 3.7 0.22 11.8 3.7 1.1 1 0 0 1 1 1 0 LIN37 Ribosomal_L34 PF00468.17 EGG07138.1 - 8.5e-21 73.7 8.2 1e-20 73.4 8.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L34 SSP160 PF06933.11 EGG07139.1 - 0.74 7.9 8.5 0.83 7.8 8.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PI3K_1B_p101 PF10486.9 EGG07139.1 - 1.2 6.8 12.6 1.3 6.7 12.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit UPF0560 PF10577.9 EGG07139.1 - 1.8 7.0 10.5 1.9 6.9 10.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Brix PF04427.18 EGG07142.1 - 1.1e-43 149.6 2.4 1.6e-43 149.0 2.4 1.2 1 0 0 1 1 1 1 Brix domain eIF-5_eIF-2B PF01873.17 EGG07143.1 - 3.3e-41 139.8 0.0 4.2e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 EGG07143.1 - 8.3e-05 22.0 0.4 0.00013 21.4 0.4 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding IF2_N PF04760.15 EGG07143.1 - 0.0062 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Lar_restr_allev PF14354.6 EGG07143.1 - 0.041 14.3 0.5 0.097 13.1 0.4 1.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-HYPF PF07503.12 EGG07143.1 - 0.095 12.5 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 HypF finger zinc_ribbon_4 PF13717.6 EGG07143.1 - 0.13 12.3 1.8 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Arc_trans_TRASH PF08394.10 EGG07143.1 - 0.19 12.1 7.0 0.7 10.3 0.2 2.4 1 1 1 2 2 2 0 Archaeal TRASH domain CxC5 PF18718.1 EGG07144.1 - 6.1e-14 52.1 2.1 1.3e-13 51.0 2.1 1.6 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG07144.1 - 0.0031 17.7 1.3 0.0099 16.1 0.0 2.3 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases P34-Arc PF04045.14 EGG07146.1 - 2.7e-104 348.1 0.0 3.2e-104 347.9 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Late_protein_L1 PF00500.18 EGG07148.1 - 0.0083 15.0 0.0 0.0083 15.0 0.0 1.0 1 0 0 1 1 1 1 L1 (late) protein ATP-synt_J PF04911.12 EGG07152.1 - 1e-21 76.2 0.8 1.2e-21 76.0 0.8 1.1 1 0 0 1 1 1 1 ATP synthase j chain zf-RING_2 PF13639.6 EGG07153.1 - 9e-09 35.5 6.8 1.5e-08 34.8 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGG07153.1 - 1.2e-06 28.7 7.0 4.1e-06 27.0 7.0 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGG07153.1 - 1.3e-05 24.9 5.7 2.6e-05 24.0 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGG07153.1 - 0.00021 21.0 4.4 0.00021 21.0 4.4 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EGG07153.1 - 0.00083 19.2 2.2 0.0016 18.3 2.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG07153.1 - 0.0032 17.3 5.6 0.0067 16.3 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EGG07153.1 - 0.017 15.2 5.0 0.033 14.3 5.0 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C2H2_6 PF13912.6 EGG07153.1 - 0.022 14.7 2.0 0.82 9.7 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4455 PF14643.6 EGG07153.1 - 0.024 13.3 0.3 0.032 12.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) FANCL_C PF11793.8 EGG07153.1 - 0.035 14.3 5.9 0.24 11.6 5.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-P11 PF03854.14 EGG07153.1 - 0.045 13.4 0.6 0.045 13.4 0.6 2.4 2 1 0 2 2 2 0 P-11 zinc finger FYVE_2 PF02318.16 EGG07153.1 - 0.1 12.8 4.4 0.18 12.1 4.4 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_UBOX PF13445.6 EGG07153.1 - 0.17 12.0 4.3 0.39 10.8 4.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGG07153.1 - 0.2 11.7 4.0 0.5 10.5 4.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGG07153.1 - 0.22 11.5 5.7 0.42 10.6 5.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain YqeY PF09424.10 EGG07154.1 - 0.026 14.6 7.4 3.1 7.9 0.2 3.6 2 2 1 3 3 3 0 Yqey-like protein TFIIB PF00382.19 EGG07155.1 - 2.3e-42 142.9 0.9 4.5e-21 74.7 0.2 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGG07155.1 - 8.3e-14 50.8 1.2 1.3e-13 50.2 1.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 EGG07155.1 - 1.5e-05 25.0 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain GerE PF00196.19 EGG07155.1 - 0.036 13.6 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EGG07155.1 - 0.037 13.7 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Cyclin_N PF00134.23 EGG07155.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain CorA PF01544.18 EGG07156.1 - 8.4e-06 25.3 1.1 1.2e-05 24.7 1.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ndc80_HEC PF03801.13 EGG07158.1 - 1.4e-32 112.4 0.0 1.4e-32 112.4 0.0 2.1 2 0 0 2 2 2 1 HEC/Ndc80p family JmjN PF02375.17 EGG07158.1 - 0.16 12.0 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 jmjN domain Ribosomal_L22 PF00237.19 EGG07158.1 - 2.5 8.4 5.9 12 6.2 0.3 2.8 2 1 0 2 2 2 0 Ribosomal protein L22p/L17e NOA36 PF06524.12 EGG07159.1 - 0.29 10.4 4.6 0.45 9.8 4.6 1.4 1 0 0 1 1 1 0 NOA36 protein DUF4692 PF15763.5 EGG07159.1 - 0.76 10.2 10.5 1.2 9.6 10.5 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Zip PF02535.22 EGG07159.1 - 1 8.5 4.5 1 8.5 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4820 PF16091.5 EGG07159.1 - 1.4 8.2 9.6 0.5 9.7 6.8 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4820) DUF5122 PF17164.4 EGG07160.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller RGS PF00615.19 EGG07161.1 - 2.9e-30 105.0 0.0 5.4e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 EGG07161.1 - 1.6e-11 44.1 0.0 6.6e-06 26.1 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Mrr_N PF14338.6 EGG07161.1 - 0.11 12.7 0.0 4.2 7.6 0.0 2.6 2 0 0 2 2 2 0 Mrr N-terminal domain NAC PF01849.18 EGG07162.1 - 7.7e-19 67.4 0.6 1.3e-18 66.7 0.6 1.4 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 EGG07162.1 - 0.015 15.1 0.0 0.042 13.7 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain Ribosomal_L30 PF00327.20 EGG07162.1 - 0.085 12.8 0.4 0.16 11.8 0.4 1.5 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e RepA_N PF06970.11 EGG07162.1 - 1.5 8.8 3.7 1.1 9.2 0.2 2.5 4 0 0 4 4 4 0 Replication initiator protein A (RepA) N-terminus DUF4588 PF15251.6 EGG07163.1 - 0.072 12.8 5.0 0.32 10.7 5.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) Nop PF01798.18 EGG07165.1 - 3.8e-80 268.6 0.3 3.8e-80 268.6 0.3 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGG07165.1 - 3.6e-18 65.7 0.3 3.6e-18 65.7 0.3 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain CEP44 PF15007.6 EGG07166.1 - 0.2 11.8 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 EOS1 PF12326.8 EGG07168.1 - 1.3 8.9 3.3 1.2 9.1 0.0 2.4 2 1 0 2 2 2 0 N-glycosylation protein 2OG-FeII_Oxy PF03171.20 EGG07170.1 - 2.1e-08 34.6 0.0 3.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGG07170.1 - 2.9e-06 28.0 0.0 4.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal RNA_Me_trans PF04252.13 EGG07171.1 - 7.7e-69 231.3 0.1 7e-66 221.6 0.1 2.2 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S8 PF00082.22 EGG07172.1 - 3.9e-46 157.7 0.0 1.2e-45 156.1 0.0 1.7 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EGG07172.1 - 1.3e-12 48.5 0.3 2.4e-12 47.6 0.3 1.5 1 0 0 1 1 1 1 Fn3-like domain Ada3 PF10198.9 EGG07173.1 - 2.4e-05 24.5 0.0 2.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Pro-kuma_activ PF09286.11 EGG07175.1 - 5e-35 120.9 0.3 1.3e-34 119.5 0.3 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGG07175.1 - 2e-07 30.6 0.4 3.4e-07 29.8 0.4 1.3 1 0 0 1 1 1 1 Subtilase family WBP-1 PF11669.8 EGG07175.1 - 0.04 14.5 0.1 4.9 7.9 0.0 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 zf-C3HC4 PF00097.25 EGG07178.1 - 1.4e-08 34.4 4.6 3.4e-08 33.2 4.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG07178.1 - 9.2e-08 31.8 6.4 3.8e-06 26.6 2.4 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG07178.1 - 3.6e-07 30.4 11.1 4.2e-06 27.0 11.1 2.2 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGG07178.1 - 2e-05 24.8 5.5 3.6e-05 24.0 5.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGG07178.1 - 2.7e-05 23.9 8.1 0.00012 21.8 3.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG07178.1 - 0.00059 19.6 7.6 0.00067 19.5 5.7 2.0 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGG07178.1 - 0.0082 16.2 4.4 0.021 14.8 4.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG07178.1 - 0.034 14.1 9.3 0.076 13.0 9.3 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGG07178.1 - 0.56 10.4 6.9 0.48 10.6 4.2 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGG07178.1 - 1.1 9.1 8.8 2.2 8.1 0.3 3.2 3 0 0 3 3 3 0 RING-like zinc finger PGM_PMM_I PF02878.16 EGG07180.1 - 9e-36 122.6 0.4 1.4e-34 118.7 0.1 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I ADH_zinc_N PF00107.26 EGG07180.1 - 1.6e-22 79.9 0.3 4.1e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PGM_PMM_II PF02879.16 EGG07180.1 - 2.7e-17 63.3 0.0 3.8e-16 59.6 0.0 2.8 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EGG07180.1 - 9e-15 54.9 0.0 2.5e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ADH_N PF08240.12 EGG07180.1 - 1.7e-12 47.2 0.0 3.5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGG07180.1 - 1e-10 42.8 0.0 2.3e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGG07180.1 - 0.00018 21.3 0.0 0.00082 19.3 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase adh_short PF00106.25 EGG07180.1 - 0.073 12.5 0.3 0.16 11.4 0.3 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Dak2 PF02734.17 EGG07180.1 - 0.09 12.7 0.3 0.21 11.5 0.3 1.6 1 0 0 1 1 1 0 DAK2 domain Gar1 PF04410.14 EGG07181.1 - 2.2e-34 118.5 0.0 2.8e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region HA2 PF04408.23 EGG07182.1 - 4.4e-21 75.2 0.0 4.4e-21 75.2 0.0 4.8 6 0 0 6 6 6 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGG07182.1 - 1.8e-17 63.4 0.0 4.5e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGG07182.1 - 1.6e-14 54.2 0.0 3.9e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG07182.1 - 0.002 17.9 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Glyco_hydro_16 PF00722.21 EGG07183.1 - 7.3e-32 110.2 0.1 9.4e-32 109.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Cactin_mid PF10312.9 EGG07184.1 - 8.6e-64 214.9 12.3 5.3e-63 212.4 12.3 2.4 1 1 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EGG07184.1 - 2.7e-58 195.3 7.3 4.9e-58 194.5 7.3 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 EGG07184.1 - 0.0059 16.9 0.0 0.021 15.2 0.0 1.9 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) SBDS PF01172.18 EGG07185.1 - 1.6e-15 56.9 0.0 2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein VSG_B PF13206.6 EGG07186.1 - 0.015 14.6 0.3 0.018 14.3 0.3 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Ribosomal_S17e PF00833.18 EGG07186.1 - 0.039 13.9 0.3 0.21 11.5 0.0 2.1 1 1 0 2 2 2 0 Ribosomal S17 Peptidase_S10 PF00450.22 EGG07187.1 - 2.3e-98 330.4 0.0 2.8e-98 330.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase VPDSG-CTERM PF18205.1 EGG07187.1 - 0.29 11.0 3.9 0.66 9.8 3.9 1.6 1 0 0 1 1 1 0 VPDSG-CTERM motif FAM60A PF15396.6 EGG07190.1 - 0.042 13.9 0.4 0.042 13.9 0.4 1.7 2 0 0 2 2 2 0 Protein Family FAM60A Proton_antipo_M PF00361.20 EGG07191.1 - 1.3e-06 27.8 0.5 1.9e-06 27.3 0.5 1.2 1 0 0 1 1 1 1 Proton-conducting membrane transporter MFS_1 PF07690.16 EGG07192.1 - 1.8e-26 92.9 25.0 1.8e-26 92.9 25.0 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EGG07192.1 - 0.0015 17.9 16.8 0.024 14.0 16.8 2.3 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB 7TM_GPCR_Srbc PF10316.9 EGG07192.1 - 0.016 14.7 12.2 0.019 14.5 1.1 2.7 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc zf-rbx1 PF12678.7 EGG07194.1 - 7.4e-22 77.4 8.4 7.4e-22 77.4 8.4 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGG07194.1 - 1.8e-14 53.6 10.3 2.3e-10 40.4 2.8 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EGG07194.1 - 3.6e-07 30.4 7.5 3.6e-07 30.4 7.5 2.3 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG07194.1 - 0.00046 20.0 6.8 0.00046 20.0 6.8 2.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGG07194.1 - 0.001 18.8 1.8 0.001 18.8 1.8 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGG07194.1 - 0.0023 17.7 8.3 0.0023 17.7 8.3 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGG07194.1 - 0.32 11.2 8.0 0.28 11.4 5.6 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EGG07194.1 - 0.56 9.9 12.5 13 5.5 12.5 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EGG07194.1 - 0.65 9.9 11.6 0.36 10.7 5.6 2.6 1 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EGG07194.1 - 1.7 8.6 9.1 1 9.3 5.2 2.2 2 0 0 2 2 2 0 PHD-finger zf-RING_UBOX PF13445.6 EGG07194.1 - 1.8 8.6 9.0 0.15 12.1 3.3 2.1 2 1 0 2 2 2 0 RING-type zinc-finger Scm3 PF10384.9 EGG07195.1 - 0.33 10.7 1.4 4.6 7.1 0.1 3.0 3 0 0 3 3 3 0 Centromere protein Scm3 Rotamase_3 PF13616.6 EGG07196.1 - 1.2e-12 48.4 0.1 3.3e-12 47.0 0.0 1.9 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EGG07196.1 - 4.7e-08 33.9 0.0 6.7e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Sigma_reg_N PF13800.6 EGG07197.1 - 0.00017 21.8 17.5 30 5.0 0.1 7.5 7 0 0 7 7 7 6 Sigma factor regulator N-terminal Ntox10 PF15520.6 EGG07198.1 - 0.026 14.4 0.4 0.28 11.1 0.2 2.1 2 0 0 2 2 2 0 Novel toxin 10 LMBR1 PF04791.16 EGG07198.1 - 0.036 13.0 0.2 0.036 13.0 0.2 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein PLA2_B PF01735.18 EGG07200.1 - 3.6e-80 269.7 0.5 8.4e-60 202.6 0.0 2.3 2 0 0 2 2 2 2 Lysophospholipase catalytic domain PLA2_B PF01735.18 EGG07201.1 - 1.2e-31 109.7 0.0 1.8e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.18 EGG07202.1 - 7.1e-86 288.6 0.0 1e-85 288.0 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Plant_tran PF04827.14 EGG07203.1 - 1.4e-22 80.4 0.1 1.9e-22 79.9 0.1 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 EGG07203.1 - 1.4e-05 24.8 0.3 2.2e-05 24.2 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Peptidase_S9 PF00326.21 EGG07204.1 - 3.6e-10 39.7 0.0 7.6e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGG07204.1 - 1.7e-05 24.2 0.0 6.6e-05 22.3 0.0 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG07204.1 - 3.1e-05 23.8 0.0 0.00011 22.0 0.0 2.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGG07204.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 EGG07204.1 - 0.034 13.9 0.0 0.16 11.8 0.0 2.0 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.14 EGG07204.1 - 0.063 12.6 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Secretory lipase MFS_1 PF07690.16 EGG07205.1 - 3.2e-09 36.2 37.7 3.7e-09 36.0 33.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MPC PF03650.13 EGG07206.1 - 8e-41 138.6 0.4 9e-41 138.5 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Suv3_C_1 PF18147.1 EGG07206.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 cobW PF02492.19 EGG07207.1 - 3.2e-31 108.3 0.0 4.2e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EGG07207.1 - 3.7e-05 22.9 0.1 0.0001 21.4 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ANTH PF07651.16 EGG07208.1 - 1.1e-71 241.0 0.0 1.1e-71 241.0 0.0 3.1 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 EGG07208.1 - 2.7e-51 173.8 9.3 2.7e-51 173.8 9.3 5.5 4 1 3 7 7 7 1 I/LWEQ domain ENTH PF01417.20 EGG07208.1 - 0.0021 18.1 0.1 0.019 15.0 0.0 2.8 2 0 0 2 2 2 1 ENTH domain FAA_hydro_N_2 PF18288.1 EGG07208.1 - 0.014 15.8 1.2 0.63 10.5 1.2 3.7 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 Lactonase PF10282.9 EGG07210.1 - 1.9e-49 168.8 0.0 3.3e-49 168.0 0.0 1.3 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PXA PF02194.15 EGG07214.1 - 8.9e-14 51.9 0.1 1.1e-13 51.5 0.1 1.2 1 0 0 1 1 1 1 PXA domain Glyco_hydro_7 PF00840.20 EGG07216.1 - 4.7e-151 503.4 0.8 5.4e-151 503.2 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Pacifastin_I PF05375.13 EGG07216.1 - 1.8 8.4 9.0 0.14 11.9 2.6 2.6 2 1 0 2 2 2 0 Pacifastin inhibitor (LCMII) Mannosyl_trans3 PF11051.8 EGG07217.1 - 5.1e-30 104.8 0.0 1.5e-19 70.5 0.0 2.2 2 0 0 2 2 2 2 Mannosyltransferase putative Troponin-I_N PF11636.8 EGG07217.1 - 0.14 12.1 0.3 0.32 11.0 0.3 1.6 1 0 0 1 1 1 0 Troponin I residues 1-32 DUF915 PF06028.11 EGG07218.1 - 0.031 13.6 0.1 0.051 12.9 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF5527 PF17665.1 EGG07220.1 - 3.9 7.0 7.6 0.78 9.3 2.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5527) Omptin PF01278.20 EGG07221.1 - 0.0023 17.0 0.8 0.33 9.9 0.0 3.5 1 1 1 3 3 3 2 Omptin family COMPASS-Shg1 PF05205.12 EGG07221.1 - 0.0064 17.2 7.1 7 7.4 1.9 4.3 1 1 2 3 3 3 2 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1943 PF09172.11 EGG07221.1 - 0.033 13.4 21.5 1.2 8.3 2.5 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF1943) MspA PF09203.11 EGG07221.1 - 0.063 13.1 25.8 0.038 13.9 6.8 3.7 1 1 1 3 3 3 0 MspA MipA PF06629.12 EGG07221.1 - 0.14 12.4 0.5 3.4 7.9 0.5 2.6 1 1 0 1 1 1 0 MltA-interacting protein MipA CEL_III_C PF18054.1 EGG07221.1 - 0.54 10.3 1.6 5.6 7.0 0.1 2.9 2 1 2 4 4 4 0 CEL-III C-terminal HAT PF02184.16 EGG07224.1 - 1.1e-24 86.0 51.8 2.4e-12 46.6 0.0 14.7 14 1 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EGG07224.1 - 2.6e-22 77.6 26.4 0.0046 17.7 0.1 12.3 4 3 8 13 13 11 7 Tetratricopeptide repeat Suf PF05843.14 EGG07224.1 - 5.7e-13 49.5 14.1 2.1e-05 24.7 0.0 6.2 1 1 2 4 4 4 4 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EGG07224.1 - 2.8e-12 47.0 0.6 0.00093 19.7 0.0 7.1 5 4 4 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG07224.1 - 1.7e-07 31.7 6.6 0.088 13.5 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG07224.1 - 2.6e-06 27.4 2.4 0.16 12.4 0.0 6.7 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG07224.1 - 5.1e-06 26.2 19.1 1.2 9.4 0.1 9.2 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG07224.1 - 9.4e-06 25.5 0.1 61 4.2 0.0 6.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGG07224.1 - 6.2e-05 22.3 17.4 0.0092 15.2 5.7 5.0 2 2 3 5 5 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGG07224.1 - 0.00049 20.1 24.0 0.039 13.9 1.7 6.2 4 1 1 5 5 5 2 Mad3/BUB1 homology region 1 SNAP PF14938.6 EGG07224.1 - 0.0018 17.8 4.5 0.0033 16.9 1.1 2.9 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EGG07224.1 - 0.0027 18.0 10.2 0.56 10.5 0.2 6.1 5 2 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG07224.1 - 0.0033 18.0 14.5 85 4.1 0.1 9.8 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG07224.1 - 0.035 14.1 6.4 10 6.4 0.0 6.0 8 0 0 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG07224.1 - 0.095 12.8 0.7 12 6.1 0.0 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 EGG07224.1 - 0.32 10.9 4.2 42 4.2 0.1 5.1 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGG07224.1 - 0.64 10.2 10.0 6.7 6.9 0.1 5.6 6 1 2 8 8 7 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 EGG07224.1 - 3 8.1 8.1 8.4 6.7 0.4 4.3 3 1 1 4 4 4 0 c-SKI Smad4 binding domain Cnd2 PF05786.14 EGG07226.1 - 1.2e-153 513.6 18.1 3.5e-81 274.0 0.0 2.9 1 1 2 3 3 3 2 Condensin complex subunit 2 Molybdopterin_N PF18364.1 EGG07229.1 - 0.093 12.8 0.2 0.28 11.2 0.2 1.8 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain SAPS PF04499.15 EGG07229.1 - 0.12 11.1 7.9 0.21 10.3 7.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 EGG07229.1 - 1.4 7.9 9.6 0.022 13.7 2.7 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 EGG07229.1 - 6.5 4.9 24.4 9.1 4.4 24.4 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM72 PF14976.6 EGG07230.1 - 0.0033 17.6 1.3 0.0087 16.2 1.3 1.6 1 0 0 1 1 1 1 FAM72 protein Syndecan PF01034.20 EGG07231.1 - 0.3 11.0 0.2 0.53 10.2 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain Carbpep_Y_N PF05388.11 EGG07232.1 - 0.043 14.4 2.2 0.093 13.3 2.2 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide mCpol PF18182.1 EGG07232.1 - 0.069 13.5 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 minimal CRISPR polymerase domain AvrM-A PF18241.1 EGG07232.1 - 0.084 13.3 0.1 0.14 12.6 0.1 1.2 1 0 0 1 1 1 0 Flax-rust effector AvrM-A zf-RING_2 PF13639.6 EGG07233.1 - 5.7e-05 23.4 0.8 0.00032 21.0 0.8 2.3 1 0 0 1 1 1 1 Ring finger domain DUF496 PF04363.12 EGG07233.1 - 0.00052 20.0 3.1 2.7 8.1 0.0 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF496) zf-RING_11 PF17123.5 EGG07233.1 - 0.23 11.3 4.4 0.22 11.3 1.7 2.4 2 0 0 2 2 2 0 RING-like zinc finger MFS_1 PF07690.16 EGG07234.1 - 2.1e-11 43.4 23.5 2.1e-11 43.4 23.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha_kinase PF02816.18 EGG07236.1 - 1.1e-06 28.9 0.1 2.3e-06 27.9 0.1 1.5 1 1 0 1 1 1 1 Alpha-kinase family Presenilin PF01080.17 EGG07237.1 - 0.054 12.3 1.7 0.082 11.7 1.7 1.3 1 0 0 1 1 1 0 Presenilin DUF1325 PF07039.11 EGG07238.1 - 2.5e-25 89.1 0.0 4e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Epimerase PF01370.21 EGG07240.1 - 3.8e-12 46.2 0.0 1.1e-10 41.5 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGG07240.1 - 1.7e-10 41.1 0.0 2.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGG07240.1 - 3.5e-09 36.1 0.0 2.6e-08 33.2 0.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EGG07240.1 - 3.6e-09 36.5 0.0 4.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EGG07240.1 - 2.9e-07 29.9 0.0 0.01 14.9 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGG07240.1 - 1.5e-06 27.6 0.0 0.00072 18.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EGG07240.1 - 0.0003 20.3 0.1 0.00056 19.4 0.1 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EGG07240.1 - 0.0034 16.8 0.0 0.0063 16.0 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG07240.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 EGG07240.1 - 0.16 11.1 0.0 0.83 8.7 0.0 2.1 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein Translin PF01997.16 EGG07243.1 - 4.6e-25 88.8 0.0 5e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Translin family CNH PF00780.22 EGG07244.1 - 3.3e-69 233.6 0.0 9.3e-69 232.1 0.0 1.7 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EGG07244.1 - 2.5e-42 144.2 0.1 4.8e-42 143.2 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EGG07244.1 - 4.6e-34 118.3 0.2 7.1e-34 117.6 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EGG07244.1 - 6.5e-14 51.7 0.0 1.4e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 EGG07244.1 - 0.00058 19.7 0.2 0.0039 17.0 0.2 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGG07244.1 - 0.0044 17.5 0.0 0.013 16.0 0.0 1.8 1 0 0 1 1 1 1 PH domain CheB_methylest PF01339.17 EGG07244.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 CheB methylesterase ATPgrasp_YheCD PF14398.6 EGG07246.1 - 0.0028 17.0 0.3 1.6 8.0 0.1 2.1 1 1 1 2 2 2 2 YheC/D like ATP-grasp Frataxin_Cyay PF01491.16 EGG07246.1 - 0.0077 16.3 0.1 0.35 11.0 0.0 2.1 1 1 1 2 2 2 2 Frataxin-like domain Pkinase PF00069.25 EGG07247.1 - 1.6e-69 234.3 0.0 2.3e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG07247.1 - 1.1e-35 123.2 0.0 1.7e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG07247.1 - 0.01 15.2 0.0 0.027 13.8 0.0 1.7 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EGG07247.1 - 0.015 15.3 0.1 0.039 13.9 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG07247.1 - 0.016 14.1 0.1 0.016 14.1 0.1 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 EGG07247.1 - 0.025 13.9 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGG07247.1 - 0.067 12.8 0.5 0.12 11.9 0.5 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EGG07247.1 - 0.079 12.6 0.1 0.27 10.8 0.1 1.7 1 1 1 2 2 2 0 RIO1 family dCMP_cyt_deam_1 PF00383.23 EGG07248.1 - 3.5e-25 87.8 0.8 5.1e-25 87.3 0.8 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGG07248.1 - 1.4e-10 41.0 0.1 2.6e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EGG07248.1 - 0.07 13.2 0.3 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 FCH PF00611.23 EGG07249.1 - 1.3e-08 35.0 0.0 5.1e-08 33.1 0.0 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.27 EGG07249.1 - 1.9e-08 34.3 0.2 4.7e-08 33.0 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain DUF4298 PF14131.6 EGG07249.1 - 0.11 12.4 0.7 0.36 10.8 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Acetyltransf_1 PF00583.25 EGG07250.1 - 2.4e-15 56.8 0.0 3e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG07250.1 - 7.8e-11 42.0 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG07250.1 - 1.3e-09 38.3 0.0 1.8e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG07250.1 - 1.5e-08 34.5 0.1 2.3e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGG07250.1 - 5.8e-06 26.4 0.0 9.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGG07250.1 - 5.8e-06 26.0 0.0 9.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGG07250.1 - 0.0011 19.1 0.1 0.0019 18.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGG07250.1 - 0.0041 17.2 0.0 0.007 16.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EGG07250.1 - 0.011 16.5 0.0 0.013 16.2 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2196 PF09962.9 EGG07250.1 - 0.016 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) Acetyltransf_13 PF13880.6 EGG07250.1 - 0.029 14.3 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase IMS PF00817.20 EGG07252.1 - 2.3e-42 144.6 0.0 4.3e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EGG07252.1 - 8.6e-12 45.8 0.0 2.8e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 EGG07252.1 - 2.9e-07 30.8 0.0 7.1e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG07252.1 - 6.7e-06 26.4 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGG07252.1 - 0.00021 21.1 0.1 0.00055 19.8 0.0 1.8 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 EGG07252.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 EGG07252.1 - 0.057 13.8 0.1 0.34 11.3 0.0 2.3 2 0 0 2 2 2 0 IMS family HHH motif LRR_4 PF12799.7 EGG07257.1 - 0.0021 18.4 8.8 0.075 13.5 0.4 4.6 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) DUF2857 PF11198.8 EGG07257.1 - 0.15 11.8 0.1 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) ACP_syn_III PF08545.10 EGG07258.1 - 0.094 12.6 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.22 EGG07258.1 - 0.16 11.2 10.2 0.16 11.2 10.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Aa_trans PF01490.18 EGG07260.1 - 2.3e-13 49.7 0.6 7.2e-08 31.5 2.0 2.5 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Vfa1 PF08432.10 EGG07260.1 - 4.5 7.6 8.8 8.1 6.7 8.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 EGG07260.1 - 5.3 5.1 14.5 8 4.5 14.5 1.2 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 EGG07260.1 - 7.9 4.1 6.5 11 3.6 6.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Acatn PF13000.7 EGG07261.1 - 4.8e-155 517.2 35.3 1.3e-82 278.1 17.8 3.7 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Porin_3 PF01459.22 EGG07262.1 - 6.5e-71 238.9 0.3 7.1e-71 238.8 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Ral PF11058.8 EGG07264.1 - 0.38 10.4 3.0 0.52 9.9 3.0 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral Cys_rich_CWC PF14375.6 EGG07265.1 - 1.9 9.0 14.1 1.4 9.4 9.3 2.3 2 0 0 2 2 2 0 Cysteine-rich CWC Antimicrobial14 PF08109.11 EGG07268.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Lactocin 705 family Dicty_REP PF05086.12 EGG07268.1 - 0.86 7.5 16.4 1.1 7.1 16.4 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FAM60A PF15396.6 EGG07268.1 - 4.5 7.2 12.8 9.6 6.1 12.8 1.6 1 0 0 1 1 1 0 Protein Family FAM60A eIF-3c_N PF05470.12 EGG07268.1 - 6.8 4.9 15.0 11 4.2 15.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus L1R_F9L PF02442.17 EGG07269.1 - 0.049 13.5 6.1 0.046 13.6 5.4 1.4 1 1 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses TMEM119 PF15724.5 EGG07269.1 - 0.28 11.2 3.2 0.19 11.8 1.4 1.5 1 1 1 2 2 2 0 TMEM119 family ETRAMP PF09716.10 EGG07269.1 - 6.1 7.0 10.1 34 4.6 10.1 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF962 PF06127.11 EGG07272.1 - 0.096 12.8 0.5 0.19 11.8 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF962) T3SSipB PF16535.5 EGG07273.1 - 2.5 8.5 11.0 0.1 13.1 1.4 2.8 2 1 1 3 3 3 0 Type III cell invasion protein SipB ZapB PF06005.12 EGG07273.1 - 9.9 6.7 12.7 0.22 12.0 3.5 2.7 3 0 0 3 3 3 0 Cell division protein ZapB CAMSAP_CH PF11971.8 EGG07275.1 - 0.089 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain Zn_clus PF00172.18 EGG07277.1 - 0.39 10.9 9.0 7.1 6.8 0.2 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC-167 PF15188.6 EGG07278.1 - 9 6.7 9.0 39 4.7 4.2 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 FAR1 PF03101.15 EGG07279.1 - 9.9e-06 26.2 1.7 9.9e-06 26.2 1.7 1.8 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.11 EGG07279.1 - 0.00027 21.3 0.6 0.00064 20.1 0.2 1.9 2 0 0 2 2 2 1 Transcription factor AFT Fumerase_C PF05683.12 EGG07279.1 - 0.0041 16.4 0.0 0.0088 15.4 0.0 1.5 1 0 0 1 1 1 1 Fumarase C-terminus UL73_N PF12522.8 EGG07283.1 - 9.7 6.1 12.7 20 5.0 12.7 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal CCDC-167 PF15188.6 EGG07284.1 - 0.026 14.8 0.4 0.048 14.0 0.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Helitron_like_N PF14214.6 EGG07286.1 - 6.1e-05 23.3 0.1 8.4e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus SIMPL PF04402.14 EGG07286.1 - 0.12 12.8 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Surp PF01805.20 EGG07287.1 - 1.8e-13 50.3 0.6 1.6e-12 47.2 0.1 2.3 2 0 0 2 2 2 1 Surp module RRM_1 PF00076.22 EGG07287.1 - 3.3e-07 30.0 0.0 0.0061 16.4 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 EGG07287.1 - 1.8e-05 25.5 0.5 0.00033 21.4 0.3 2.5 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.8 EGG07287.1 - 7.2e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 RSRP PF17069.5 EGG07287.1 - 7.4 6.1 57.9 19 4.7 57.9 1.6 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Ribosomal_S8e PF01201.22 EGG07288.1 - 1.4e-41 141.8 2.1 2.2e-41 141.2 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Aldo_ket_red PF00248.21 EGG07289.1 - 2.7e-65 220.5 0.0 3.2e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mak10 PF04112.13 EGG07291.1 - 9e-30 103.4 0.8 7e-29 100.5 0.8 2.1 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Pkinase PF00069.25 EGG07292.1 - 2.7e-55 187.6 0.0 3.3e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG07292.1 - 1.6e-30 106.3 0.0 3.7e-30 105.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG07292.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGG07292.1 - 0.0075 16.2 0.0 0.03 14.3 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGG07292.1 - 0.026 13.3 0.0 0.056 12.2 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase ATPase_gene1 PF09527.10 EGG07293.1 - 0.012 15.8 2.1 0.012 15.8 2.1 3.1 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Collectrin PF16959.5 EGG07293.1 - 0.21 11.4 1.3 0.99 9.2 0.5 2.3 2 0 0 2 2 2 0 Renal amino acid transporter ATPase_gene1 PF09527.10 EGG07294.1 - 0.0081 16.3 1.9 0.0081 16.3 1.9 3.4 3 0 0 3 3 3 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Colicin_V PF02674.16 EGG07294.1 - 3.2 7.7 13.0 25 4.8 0.5 4.2 4 1 0 4 4 4 0 Colicin V production protein DUF2721 PF11026.8 EGG07294.1 - 3.5 7.5 10.0 0.13 12.1 0.5 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) ATG27 PF09451.10 EGG07295.1 - 1.2e-44 153.1 0.0 1.5e-44 152.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EGG07295.1 - 4.2e-07 30.1 0.0 0.00062 19.9 0.0 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF3492 PF11997.8 EGG07299.1 - 0.067 12.9 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) LysM PF01476.20 EGG07300.1 - 3e-06 27.2 0.0 6.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 LysM domain CASP_C PF08172.12 EGG07301.1 - 4.2e-76 255.6 2.9 4.2e-76 255.6 2.9 4.3 2 1 2 4 4 4 1 CASP C terminal KLRAQ PF10205.9 EGG07301.1 - 0.0083 16.4 0.3 0.0083 16.4 0.3 6.6 4 2 3 7 7 7 1 Predicted coiled-coil domain-containing protein Pedibin PF08182.11 EGG07301.1 - 0.32 10.8 12.5 0.5 10.2 0.4 4.5 4 0 0 4 4 4 0 Pedibin/Hym-346 family WD40_alt PF14077.6 EGG07301.1 - 4 7.4 7.8 24 4.9 0.5 4.1 3 0 0 3 3 3 0 Alternative WD40 repeat motif CxC5 PF18718.1 EGG07303.1 - 0.057 13.5 0.7 0.095 12.8 0.2 1.7 2 0 0 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases Rhodanese PF00581.20 EGG07305.1 - 7e-13 49.0 0.0 1.1e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain RlmM_FDX PF18125.1 EGG07305.1 - 0.064 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 RlmM ferredoxin-like domain RPEL PF02755.15 EGG07307.1 - 2.6e-15 55.6 8.6 1.6e-07 30.8 0.7 2.9 3 1 0 3 3 3 2 RPEL repeat MIase PF02426.16 EGG07309.1 - 0.031 14.4 0.1 0.13 12.4 0.1 2.0 2 0 0 2 2 2 0 Muconolactone delta-isomerase SSP160 PF06933.11 EGG07309.1 - 1.8 6.7 6.0 2.9 6.0 6.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NDUF_B12 PF08122.12 EGG07310.1 - 2.9e-18 65.7 0.2 3.3e-18 65.5 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Tyrosinase PF00264.20 EGG07311.1 - 1.1e-27 97.8 6.4 1.9e-27 97.0 6.4 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Baculo_LEF-2 PF03041.14 EGG07312.1 - 0.0053 16.4 1.3 0.0066 16.1 1.3 1.1 1 0 0 1 1 1 1 lef-2 LRR_1 PF00560.33 EGG07313.1 - 0.017 15.5 3.3 5.3 8.0 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 EGG07313.1 - 0.025 14.6 1.7 3.3 8.0 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 EGG07313.1 - 1.7 9.2 9.8 2.4 8.7 0.1 4.1 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) CcmD PF04995.14 EGG07315.1 - 0.12 12.4 0.5 0.18 11.9 0.5 1.1 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF1674 PF07896.12 EGG07316.1 - 7.1e-19 68.0 3.2 1.4e-18 67.1 3.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) DUF1279 PF06916.13 EGG07317.1 - 8.4e-18 64.7 0.8 1.7e-17 63.8 0.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF1115 PF06544.12 EGG07317.1 - 0.0059 16.7 0.0 0.0077 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Aminotran_4 PF01063.19 EGG07318.1 - 2.4e-22 79.9 0.0 3e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 EGG07319.1 - 1.1e-38 133.1 0.0 6.1e-38 130.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG07319.1 - 3.5e-24 85.5 0.0 1.3e-22 80.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase ATP-synt_DE_N PF02823.16 EGG07320.1 - 4.1e-18 65.1 0.1 5.3e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain PWWP PF00855.17 EGG07321.1 - 3.5e-18 65.8 1.6 6.2e-18 65.0 0.0 2.2 2 0 0 2 2 2 1 PWWP domain Skp1 PF01466.19 EGG07321.1 - 0.01 15.9 0.2 0.039 14.1 0.2 2.0 1 0 0 1 1 1 0 Skp1 family, dimerisation domain RBB1NT PF08169.11 EGG07321.1 - 0.033 14.3 0.4 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 RBB1NT (NUC162) domain CD24 PF14984.6 EGG07321.1 - 0.38 11.0 1.4 1.2 9.4 1.4 1.9 1 0 0 1 1 1 0 CD24 protein RTT107_BRCT_5 PF16770.5 EGG07323.1 - 8.6e-09 35.2 0.0 2.5e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 EGG07323.1 - 8.8e-07 29.3 0.1 0.025 15.0 0.0 2.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG07323.1 - 7.2e-05 23.1 0.2 0.021 15.2 0.1 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Pyrid_ox_like PF16242.5 EGG07324.1 - 1.2e-30 106.0 0.5 1.9e-30 105.4 0.5 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EGG07324.1 - 1.1e-09 38.3 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Vint PF14623.6 EGG07325.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Hint-domain Peptidase_M48 PF01435.18 EGG07326.1 - 1.1e-28 100.4 0.0 1.6e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Cadherin_C_2 PF16492.5 EGG07329.1 - 0.067 14.0 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal C_GCAxxG_C_C PF09719.10 EGG07329.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) TMEM132D_C PF15706.5 EGG07329.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term RMF PF04957.12 EGG07330.1 - 0.032 14.5 0.3 0.39 11.0 0.2 2.9 2 1 1 3 3 3 0 Ribosome modulation factor SPC22 PF04573.12 EGG07331.1 - 3e-51 173.3 0.0 3.5e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Nucleo_P87 PF07267.11 EGG07332.1 - 2.1 7.1 8.2 2.5 6.8 8.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FtsJ PF01728.19 EGG07334.1 - 1.6e-30 106.5 0.0 2.4e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase TT_ORF2 PF02957.15 EGG07335.1 - 0.19 12.6 0.3 0.25 12.3 0.3 1.2 1 0 0 1 1 1 0 TT viral ORF2 PALP PF00291.25 EGG07336.1 - 4.4e-65 220.0 0.0 5e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GIDA PF01134.22 EGG07337.1 - 2.2e-152 507.7 0.0 3.1e-152 507.2 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EGG07337.1 - 5.6e-67 226.0 0.1 1e-66 225.2 0.1 1.4 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 EGG07337.1 - 5.6e-08 32.4 0.2 1.3e-07 31.2 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGG07337.1 - 7.7e-05 22.2 0.4 0.00015 21.3 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG07337.1 - 0.00042 19.1 1.5 0.73 8.5 0.1 3.3 3 0 0 3 3 3 3 HI0933-like protein FAD_binding_2 PF00890.24 EGG07337.1 - 0.0084 15.2 0.8 0.0084 15.2 0.8 1.6 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EGG07337.1 - 0.061 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Protoglobin PF11563.8 EGG07338.1 - 8.8e-23 80.9 0.0 2.3e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 Protoglobin Nuc_sug_transp PF04142.15 EGG07339.1 - 8.5e-65 219.0 5.8 9.4e-65 218.8 5.8 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EGG07339.1 - 9.8e-07 28.3 1.3 1.4e-06 27.7 1.3 1.3 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 EGG07339.1 - 4.2e-06 26.2 10.8 7.4e-06 25.4 10.8 1.5 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 EGG07339.1 - 7.1e-05 23.0 16.0 0.00019 21.6 5.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EGG07339.1 - 0.0044 16.4 1.2 0.0044 16.4 1.2 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family Tim17 PF02466.19 EGG07340.1 - 5.4e-32 110.5 8.7 6.8e-32 110.1 8.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family F-box-like PF12937.7 EGG07341.1 - 0.0033 17.3 1.0 0.026 14.4 1.0 2.5 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EGG07341.1 - 0.0067 16.8 8.2 6.8 7.3 0.1 5.2 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.33 EGG07341.1 - 0.063 13.2 5.3 0.55 10.2 0.2 3.7 4 0 0 4 4 4 0 F-box domain FAM195 PF14799.6 EGG07341.1 - 0.22 11.9 1.1 0.48 10.8 0.2 2.0 2 1 0 2 2 2 0 FAM195 family FAD_binding_1 PF00667.20 EGG07344.1 - 1.8e-57 194.5 0.0 6.8e-40 137.0 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain Flavodoxin_1 PF00258.25 EGG07344.1 - 2.3e-36 125.1 0.5 6.1e-36 123.8 0.5 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGG07344.1 - 1.9e-22 79.9 0.1 1.4e-21 77.2 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Phos_pyr_kin PF08543.12 EGG07345.1 - 5.8e-82 274.8 0.1 1.1e-81 273.9 0.1 1.4 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EGG07345.1 - 1.3e-46 159.1 0.1 1.8e-46 158.6 0.1 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 EGG07345.1 - 2.9e-06 26.8 0.0 5.8e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PMT PF02366.18 EGG07346.1 - 0.094 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase GCS PF03074.16 EGG07347.1 - 7.6e-157 522.3 0.0 9.2e-157 522.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 EGG07347.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) PIN_5 PF08745.11 EGG07347.1 - 0.085 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 PINc domain ribonuclease CBFD_NFYB_HMF PF00808.23 EGG07348.1 - 2.9e-10 40.3 0.7 4.6e-10 39.6 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGG07348.1 - 0.00032 21.0 1.5 0.00047 20.5 1.5 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RunxI PF08504.11 EGG07349.1 - 0.19 12.4 2.1 0.14 12.9 1.4 1.2 1 1 0 1 1 1 0 Runx inhibition domain PLA2_B PF01735.18 EGG07350.1 - 8.4e-81 271.8 4.7 5.4e-57 193.3 0.4 2.6 1 1 1 2 2 2 2 Lysophospholipase catalytic domain Scs3p PF10261.9 EGG07351.1 - 1.3e-56 191.8 8.0 4e-44 151.0 0.1 2.2 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM TMEM223 PF14640.6 EGG07351.1 - 0.003 17.7 0.1 0.0061 16.7 0.1 1.5 1 0 0 1 1 1 1 Transmembrane protein 223 CxC5 PF18718.1 EGG07352.1 - 7e-31 106.7 9.1 9.2e-31 106.3 9.1 1.2 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Zn_clus PF00172.18 EGG07354.1 - 0.00014 21.9 9.1 0.00026 21.1 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S9 PF00380.19 EGG07355.1 - 1e-25 90.6 0.5 1.8e-25 89.8 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Acetyltransf_1 PF00583.25 EGG07356.1 - 2.4e-11 43.9 0.0 3.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG07356.1 - 1e-09 38.4 0.0 1.9e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG07356.1 - 2.2e-09 37.6 0.0 3.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG07356.1 - 4.1e-08 33.1 0.0 7.1e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 EGG07356.1 - 7.7e-06 25.5 0.1 1.1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase PEPCK_ATP PF01293.20 EGG07357.1 - 2.6e-216 718.8 0.0 3.1e-216 718.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 EGG07357.1 - 0.077 13.1 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain 2-Hacid_dh_C PF02826.19 EGG07359.1 - 5.6e-47 159.4 0.0 8.4e-47 158.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGG07359.1 - 1.2e-22 80.0 0.0 1.6e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGG07359.1 - 0.02 15.1 0.0 0.21 11.8 0.0 2.2 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EGG07359.1 - 0.057 13.5 0.0 1.1 9.3 0.0 2.5 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.25 EGG07360.1 - 3.5e-52 177.4 0.2 3.4e-51 174.1 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG07360.1 - 6.9e-22 78.0 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG07360.1 - 0.00051 20.0 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGG07360.1 - 0.0015 18.2 0.2 0.0042 16.7 0.2 1.7 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGG07360.1 - 0.04 13.5 0.6 0.12 12.0 0.2 2.0 2 1 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 EGG07360.1 - 0.078 12.3 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thaumatin PF00314.17 EGG07361.1 - 2.3e-68 230.1 8.7 2.6e-68 229.9 8.7 1.0 1 0 0 1 1 1 1 Thaumatin family FAD_binding_6 PF00970.24 EGG07362.1 - 1.4e-34 118.3 0.0 2.6e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGG07362.1 - 6.7e-26 91.1 0.0 1.3e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGG07362.1 - 3.7e-07 30.4 0.0 6.4e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EGG07362.1 - 0.0053 17.0 0.0 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain TPP_enzyme_N PF02776.18 EGG07363.1 - 1.9e-36 125.2 0.0 2.8e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGG07363.1 - 2.3e-22 79.2 0.0 5.3e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EGG07363.1 - 4.3e-14 52.6 0.5 1.8e-13 50.5 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EGG07363.1 - 0.033 13.4 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase PP2C PF00481.21 EGG07364.1 - 1.9e-44 152.2 0.1 1.2e-43 149.6 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 EGG07364.1 - 2.1e-41 139.2 73.4 1.9e-06 28.1 0.7 13.0 6 3 9 15 15 15 15 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG07364.1 - 5.9e-41 138.0 77.3 8.2e-11 41.5 3.0 10.3 6 3 7 13 13 13 11 Leucine rich repeat Guanylate_cyc PF00211.20 EGG07364.1 - 9.6e-25 87.3 0.0 1.8e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_5 PF13306.6 EGG07364.1 - 5.5e-08 32.8 9.0 0.054 13.5 3.8 4.7 3 1 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 EGG07364.1 - 0.0038 16.7 23.7 0.21 11.1 1.8 5.1 2 2 2 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 EGG07364.1 - 0.039 14.5 61.4 0.13 12.9 0.2 14.8 15 1 0 15 15 15 0 Leucine Rich Repeat Peroxidase_2 PF01328.17 EGG07365.1 - 1.6e-39 136.4 0.0 2.1e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 UDPG_MGDP_dh_N PF03721.14 EGG07368.1 - 1.5e-60 204.0 0.0 3.6e-60 202.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EGG07368.1 - 1.1e-33 115.7 0.1 7.8e-33 113.0 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 EGG07368.1 - 1.1e-29 102.4 0.0 2.1e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain OTCace PF00185.24 EGG07368.1 - 0.0035 17.4 0.0 0.072 13.2 0.0 2.2 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Sacchrp_dh_NADP PF03435.18 EGG07368.1 - 0.01 16.1 0.0 0.037 14.3 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain UPF0086 PF01868.16 EGG07368.1 - 0.019 14.9 0.2 0.087 12.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function UPF0086 3HCDH_N PF02737.18 EGG07368.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 EGG07368.1 - 0.14 12.3 0.0 2.4 8.2 0.0 3.0 4 0 0 4 4 4 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGG07368.1 - 0.15 12.2 0.0 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase G-alpha PF00503.20 EGG07370.1 - 2e-77 260.8 0.0 2.3e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGG07370.1 - 7.5e-14 51.6 1.4 8e-09 35.2 0.0 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family MCM PF00493.23 EGG07370.1 - 0.00052 19.2 0.1 0.00082 18.5 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain Gtr1_RagA PF04670.12 EGG07370.1 - 0.0027 17.1 3.2 0.76 9.1 3.2 2.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EGG07370.1 - 0.014 15.1 0.3 0.038 13.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 EGG07370.1 - 0.015 15.5 0.2 1.1 9.5 0.1 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NMO PF03060.15 EGG07371.1 - 2.9e-52 178.1 1.8 4.8e-50 170.8 1.8 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGG07371.1 - 5.3e-10 38.8 3.3 5e-08 32.3 3.3 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGG07371.1 - 0.002 17.2 0.4 0.0028 16.7 0.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 EGG07371.1 - 0.0043 16.3 0.4 0.0068 15.6 0.4 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 EGG07371.1 - 0.0054 15.9 0.2 0.0093 15.1 0.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EGG07371.1 - 0.013 14.9 0.3 0.024 14.1 0.3 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF561 PF04481.12 EGG07371.1 - 0.13 11.4 2.5 0.75 8.9 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF561) RIFIN PF02009.16 EGG07374.1 - 0.00012 22.1 0.6 0.0002 21.4 0.2 1.4 2 0 0 2 2 2 1 Rifin DUF4690 PF15756.5 EGG07374.1 - 0.018 15.6 0.2 0.018 15.6 0.2 2.9 1 1 3 4 4 4 0 Small Novel Rich in Cartilage Orf78 PF06024.12 EGG07374.1 - 0.084 13.2 1.5 0.22 11.8 0.1 2.3 1 1 1 2 2 2 0 Orf78 (ac78) ABC2_membrane_3 PF12698.7 EGG07374.1 - 0.16 11.0 2.4 0.077 12.1 0.3 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF1539 PF07560.11 EGG07374.1 - 0.56 10.3 4.1 13 5.9 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) STAC2_u1 PF16664.5 EGG07375.1 - 0.045 14.2 0.3 0.046 14.2 0.3 1.1 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Corazonin PF17308.2 EGG07375.1 - 0.07 13.5 0.0 0.084 13.2 0.0 1.1 1 0 0 1 1 1 0 Pro-corazonin Aconitase PF00330.20 EGG07377.1 - 8.2e-150 499.8 0.0 1e-149 499.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGG07377.1 - 8.5e-34 116.7 0.0 1.5e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain FAD_binding_1 PF00667.20 EGG07377.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain OPT PF03169.15 EGG07378.1 - 4.3e-89 299.8 35.6 5.3e-89 299.5 35.6 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4470 PF14737.6 EGG07380.1 - 7.2e-11 42.1 0.0 1.5e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 EGG07380.1 - 4e-05 23.2 0.1 0.00012 21.7 0.1 1.9 1 1 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EGG07380.1 - 0.022 14.9 0.1 0.21 11.8 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGG07380.1 - 0.16 12.5 0.2 7.1 7.2 0.2 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat H_lectin PF09458.10 EGG07385.1 - 0.081 13.1 0.4 20 5.5 0.0 2.9 3 0 0 3 3 3 0 H-type lectin domain ApbA_C PF08546.11 EGG07386.1 - 4.8e-21 75.3 0.0 1.3e-20 73.8 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EGG07386.1 - 7.2e-17 61.4 0.0 1.2e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Septin PF00735.18 EGG07389.1 - 1.8e-113 378.5 0.0 2.4e-113 378.1 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGG07389.1 - 8.9e-08 32.2 0.0 2.3e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG07389.1 - 2.9e-07 30.5 0.4 2.2e-06 27.7 0.0 2.3 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 EGG07389.1 - 3.8e-06 26.6 0.2 0.00017 21.2 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 EGG07389.1 - 9.4e-05 22.1 0.2 0.00025 20.7 0.2 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG07389.1 - 0.00083 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EGG07389.1 - 0.00091 19.6 0.0 0.0037 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG07389.1 - 0.002 18.4 0.4 0.0057 16.9 0.1 2.0 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGG07389.1 - 0.002 18.6 0.8 0.053 14.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.16 EGG07389.1 - 0.0034 16.8 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family PduV-EutP PF10662.9 EGG07389.1 - 0.0044 16.8 0.3 0.18 11.6 0.3 2.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF3987 PF13148.6 EGG07389.1 - 0.009 15.1 0.1 0.8 8.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_7 PF12775.7 EGG07389.1 - 0.018 14.6 0.1 0.034 13.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 EGG07389.1 - 0.028 14.3 0.5 0.97 9.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_24 PF13479.6 EGG07389.1 - 0.048 13.4 0.4 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGG07389.1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EGG07389.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EGG07389.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.12 EGG07389.1 - 0.1 12.0 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein MobB PF03205.14 EGG07389.1 - 0.14 12.1 0.1 0.41 10.5 0.1 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.23 EGG07389.1 - 0.34 10.9 5.3 6.1 6.9 0.1 2.8 2 1 1 3 3 3 0 Dynamin family Cep57_CLD_2 PF14197.6 EGG07389.1 - 4.9 7.3 7.5 3.3 7.9 4.5 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Tim54 PF11711.8 EGG07390.1 - 5.5e-35 120.9 0.0 7e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Not3 PF04065.15 EGG07392.1 - 0.017 14.5 0.3 0.021 14.3 0.3 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component PKcGMP_CC PF16808.5 EGG07392.1 - 0.1 12.5 2.8 0.21 11.5 2.8 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Med7 PF05983.11 EGG07393.1 - 0.036 14.2 0.2 0.073 13.2 0.2 1.6 1 1 0 1 1 1 0 MED7 protein CPSF100_C PF13299.6 EGG07393.1 - 1.3 9.2 4.7 7.1 6.8 1.1 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Sigma70_ner PF04546.13 EGG07393.1 - 4.1 7.2 14.2 1.8 8.4 5.4 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Sec3_C PF09763.9 EGG07394.1 - 2.5e-148 495.5 1.8 3.7e-148 495.0 1.8 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Vps52 PF04129.12 EGG07394.1 - 2.2e-06 26.7 0.2 9.4e-06 24.6 0.2 2.0 2 0 0 2 2 2 1 Vps52 / Sac2 family DUF16 PF01519.16 EGG07394.1 - 1.9 9.0 7.6 5.8 7.5 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 Sugarporin_N PF11471.8 EGG07399.1 - 0.0031 17.4 2.8 0.011 15.7 2.8 1.9 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension DUF4639 PF15479.6 EGG07399.1 - 0.13 11.2 11.9 0.01 14.9 6.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4639) DUF4094 PF13334.6 EGG07399.1 - 0.5 10.8 5.0 0.48 10.9 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) ORF6C PF10552.9 EGG07399.1 - 7 6.8 8.8 8.9 6.4 1.0 2.5 2 0 0 2 2 2 0 ORF6C domain BUD22 PF09073.10 EGG07401.1 - 0.068 12.5 4.7 0.09 12.1 4.7 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 EGG07402.1 - 0.46 10.2 4.1 0.69 9.7 4.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PGM_PMM_I PF02878.16 EGG07404.1 - 7.3e-13 48.4 0.0 4e-08 33.1 0.0 3.1 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EGG07404.1 - 1.3e-09 38.1 0.2 3e-09 36.9 0.2 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EGG07404.1 - 3.9e-05 23.8 0.0 7.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGG07404.1 - 0.004 17.7 0.1 0.076 13.7 0.0 3.0 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SAPS PF04499.15 EGG07406.1 - 9.5e-103 344.6 0.6 1.6e-102 343.9 0.0 1.6 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Pkinase_fungal PF17667.1 EGG07407.1 - 2.5e-13 49.6 0.4 9.2e-08 31.3 0.1 2.7 2 1 0 2 2 2 2 Fungal protein kinase Mrpl_C PF18502.1 EGG07407.1 - 0.1 12.9 2.1 0.3 11.4 2.1 1.8 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain Cyd_oper_YbgE PF09600.10 EGG07409.1 - 0.0023 18.3 2.5 2.4 8.6 0.2 3.0 1 1 3 4 4 4 3 Cyd operon protein YbgE (Cyd_oper_YbgE) SNAPc_SNAP43 PF09808.9 EGG07409.1 - 0.028 14.4 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 BTB PF00651.31 EGG07409.1 - 7.1 6.9 5.9 51 4.2 0.3 3.1 1 1 3 4 4 4 0 BTB/POZ domain CxC5 PF18718.1 EGG07413.1 - 2.2e-31 108.4 6.9 3.7e-31 107.6 6.9 1.4 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases NADH_dh_m_C1 PF15088.6 EGG07414.1 - 0.089 12.4 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Ribosomal_L14 PF00238.19 EGG07416.1 - 1e-34 119.2 0.0 1.1e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF3341 PF11821.8 EGG07417.1 - 0.086 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Mito_carr PF00153.27 EGG07418.1 - 9.9e-70 230.6 0.3 1.2e-23 82.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EGG07418.1 - 3.2e-15 54.4 1.0 3.8e-05 22.9 0.7 5.8 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 EGG07418.1 - 5.2e-14 52.4 6.5 7.6e-08 32.7 0.7 4.3 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 EGG07418.1 - 5.2e-14 50.9 4.4 0.00018 21.2 0.6 5.6 7 0 0 7 7 7 3 EF-hand domain EF-hand_8 PF13833.6 EGG07418.1 - 1.1e-08 34.8 3.0 0.015 15.1 0.7 4.6 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG07418.1 - 0.00018 20.8 1.0 0.063 12.8 0.8 3.6 3 0 0 3 3 3 1 EF hand MPLKIP PF15502.6 EGG07419.1 - 2.7e-08 33.9 0.9 5.5e-08 32.9 0.1 1.8 1 1 1 2 2 2 1 M-phase-specific PLK1-interacting protein API5 PF05918.11 EGG07419.1 - 1.7 7.4 4.3 2 7.1 4.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.32 EGG07420.1 - 3.5e-21 75.1 14.4 0.00013 22.7 0.5 6.8 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG07420.1 - 2.3e-08 34.2 0.4 0.11 12.8 0.0 4.6 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG07420.1 - 0.029 13.3 0.0 2 7.3 0.0 3.3 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein tRNA-synt_1 PF00133.22 EGG07421.1 - 4.5e-206 685.7 0.0 5.4e-205 682.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGG07421.1 - 4.1e-36 124.2 0.0 1.1e-35 122.8 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGG07421.1 - 1.1e-14 54.0 0.1 1.4e-06 27.3 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGG07421.1 - 3.7e-05 23.3 0.1 0.18 11.3 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 EGG07421.1 - 4.4e-05 23.7 1.6 0.00011 22.4 1.6 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1f PF01921.18 EGG07421.1 - 0.045 12.7 0.0 0.14 11.0 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) ABC_tran_CTD PF16326.5 EGG07421.1 - 0.64 10.3 3.2 2.6 8.3 3.3 2.0 1 1 0 1 1 1 0 ABC transporter C-terminal domain Csm1_N PF18504.1 EGG07421.1 - 1.1 9.7 3.8 12 6.3 0.3 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain FlxA PF14282.6 EGG07421.1 - 6.8 6.7 8.6 20 5.3 8.6 1.7 1 0 0 1 1 1 0 FlxA-like protein Olduvai PF06758.13 EGG07422.1 - 3.5 7.9 7.2 7 7.0 2.8 2.4 2 1 0 2 2 2 0 Olduvai domain DUF4470 PF14737.6 EGG07423.1 - 9e-12 45.0 0.0 2e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.17 EGG07423.1 - 1.9e-06 27.6 0.7 0.011 15.8 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG07423.1 - 0.00015 21.4 0.1 0.00043 19.9 0.1 1.9 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 EGG07423.1 - 0.0017 18.1 1.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG07423.1 - 0.0056 16.9 1.5 1.9e+02 2.4 0.1 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGG07423.1 - 0.015 15.1 0.7 0.14 12.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG07423.1 - 0.033 14.2 0.3 1.4 9.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG07423.1 - 0.083 13.7 0.7 8.8 7.4 0.0 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF4470 PF14737.6 EGG07424.1 - 2.5e-11 43.6 0.0 5.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.17 EGG07424.1 - 8.5e-05 22.4 0.2 0.32 11.2 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG07424.1 - 0.00072 19.2 0.0 0.0019 17.8 0.0 1.8 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 EGG07424.1 - 0.0075 16.0 0.4 0.068 13.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG07424.1 - 0.049 13.9 0.5 0.19 12.0 0.6 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF3337 PF11816.8 EGG07426.1 - 2.5e-42 144.7 0.0 4.3e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EGG07426.1 - 1.1e-16 60.9 22.2 6.4e-06 26.8 0.8 7.1 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG07426.1 - 6.9e-06 26.3 0.1 0.059 13.7 0.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG07426.1 - 0.0042 16.1 0.1 0.023 13.7 0.0 2.1 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CxC5 PF18718.1 EGG07428.1 - 1.1e-32 112.6 4.3 1.7e-32 111.9 4.3 1.4 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG07428.1 - 0.00028 21.1 1.2 0.00039 20.6 0.0 1.9 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases Ribosom_S12_S23 PF00164.25 EGG07431.1 - 1.9e-46 156.3 0.3 2.4e-46 156.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Cyclin_C_2 PF16899.5 EGG07432.1 - 3.5e-13 49.9 0.3 4.9e-08 33.3 0.0 2.6 2 1 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EGG07432.1 - 1.4e-10 41.0 0.4 1.4e-10 41.0 0.4 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 EGG07432.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat CAP_GLY PF01302.25 EGG07434.1 - 2.6e-07 30.6 0.1 4.1e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain ERM PF00769.19 EGG07435.1 - 0.0013 18.7 22.6 0.0013 18.7 22.6 3.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Baculo_PEP_C PF04513.12 EGG07435.1 - 5.1 7.1 16.2 4.8 7.2 2.0 4.1 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EGG07435.1 - 7.9 5.3 48.1 0.14 11.0 10.0 3.3 3 0 0 3 3 3 0 Spc7 kinetochore protein ALG11_N PF15924.5 EGG07436.1 - 1.2e-87 293.4 0.7 1.2e-87 293.4 0.7 1.9 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EGG07436.1 - 4e-20 72.0 0.0 6.5e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGG07436.1 - 1.4e-09 38.5 0.0 2.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGG07436.1 - 0.079 12.9 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ACBP PF00887.19 EGG07437.1 - 2.6e-12 46.8 0.0 4.6e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank PF00023.30 EGG07437.1 - 1.6e-10 40.9 0.1 4.2e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EGG07437.1 - 1.1e-08 35.5 0.0 2.6e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG07437.1 - 6.4e-07 29.5 0.0 1.9e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG07437.1 - 2.7e-06 27.3 0.0 9.8e-06 25.6 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 EGG07437.1 - 9.9e-05 22.8 0.0 0.00021 21.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Glyco_hydro_cc PF11790.8 EGG07438.1 - 0.0025 17.4 0.7 0.0071 15.9 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core CBFD_NFYB_HMF PF00808.23 EGG07439.1 - 2e-19 69.6 0.3 3.8e-19 68.7 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGG07439.1 - 3.1e-05 24.3 0.2 0.00016 22.0 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 RNA_pol_Rpc34 PF05158.12 EGG07439.1 - 0.0039 16.6 0.1 0.0049 16.3 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TFIID-18kDa PF02269.16 EGG07439.1 - 0.047 13.7 0.1 0.092 12.8 0.1 1.7 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit MeaB PF03308.16 EGG07439.1 - 0.054 12.5 0.1 0.064 12.2 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF29 PF01724.16 EGG07442.1 - 0.41 10.9 2.7 4.1 7.6 1.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF29 ANAPC5 PF12862.7 EGG07443.1 - 2.2e-07 30.9 4.4 2.2e-07 30.9 4.4 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 Pkinase PF00069.25 EGG07444.1 - 5.5e-20 71.8 0.0 9.2e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EGG07444.1 - 2.4e-10 40.8 9.5 3.1e-06 27.8 0.4 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 EGG07444.1 - 1.5e-08 34.2 0.0 2.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 EGG07444.1 - 9.4e-07 28.6 3.6 0.73 10.3 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 EGG07444.1 - 0.0015 18.9 0.2 0.21 12.0 0.2 3.3 3 1 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 EGG07444.1 - 0.018 15.1 0.3 5.1 7.1 0.0 3.2 1 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EGG07444.1 - 0.082 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Ge1_WD40 PF16529.5 EGG07444.1 - 0.12 11.4 0.2 0.22 10.4 0.2 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Muskelin_N PF06588.11 EGG07447.1 - 2.5e-52 177.7 0.0 5.7e-52 176.5 0.0 1.5 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_5 PF13854.6 EGG07447.1 - 2e-17 62.8 0.1 0.00063 19.7 0.0 5.6 5 1 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EGG07447.1 - 2.3e-14 53.1 5.5 0.0034 17.4 0.0 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGG07447.1 - 5.3e-13 48.9 8.9 0.0026 18.0 0.4 6.9 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EGG07447.1 - 1.6e-10 40.8 0.4 0.12 12.7 0.0 6.4 7 0 0 7 7 7 3 Kelch motif Sad1_UNC PF07738.13 EGG07447.1 - 6.7e-05 22.9 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CLTH PF10607.9 EGG07447.1 - 0.015 15.2 0.3 0.029 14.3 0.3 1.4 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Kelch_1 PF01344.25 EGG07447.1 - 0.071 12.7 2.7 38 4.0 0.0 4.4 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 EGG07447.1 - 2 8.5 9.7 81 3.4 0.4 5.4 5 1 0 5 5 5 0 Kelch motif NPV_P10 PF05531.12 EGG07449.1 - 0.021 15.3 0.7 0.042 14.3 0.7 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1993 PF09351.10 EGG07449.1 - 0.024 14.8 0.4 0.051 13.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DUF948 PF06103.11 EGG07449.1 - 0.13 12.5 1.6 0.28 11.4 1.6 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HAP1_N PF04849.13 EGG07451.1 - 0.0023 17.2 0.3 0.0032 16.7 0.3 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region HNF-1_N PF04814.13 EGG07451.1 - 0.012 16.3 0.3 0.02 15.5 0.3 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus bZIP_1 PF00170.21 EGG07451.1 - 0.054 13.6 1.3 0.11 12.7 1.3 1.5 1 1 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.18 EGG07451.1 - 0.11 12.8 0.5 0.28 11.5 0.3 1.7 1 1 0 1 1 1 0 TSC-22/dip/bun family UPF0242 PF06785.11 EGG07451.1 - 0.14 12.3 0.3 0.2 11.8 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Apt1 PF10351.9 EGG07451.1 - 0.17 10.7 0.1 0.22 10.3 0.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ABC_tran_CTD PF16326.5 EGG07451.1 - 0.19 12.0 5.4 0.37 11.1 5.4 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain ADIP PF11559.8 EGG07451.1 - 0.2 11.7 2.1 0.3 11.2 2.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 EGG07451.1 - 0.26 11.8 2.9 0.93 10.0 2.8 1.8 1 1 0 1 1 1 0 Cell division protein ZapB AA_kinase PF00696.28 EGG07452.1 - 4.2e-38 131.3 0.1 6.2e-38 130.7 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EGG07452.1 - 5.2e-14 52.0 0.1 2.1e-13 50.0 0.1 2.0 1 1 0 1 1 1 1 PUA domain SAP PF02037.27 EGG07453.1 - 6.6e-11 41.7 0.2 1.5e-10 40.6 0.2 1.6 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 EGG07453.1 - 4.1e-08 32.9 5.2 2.5e-05 24.0 2.0 2.6 2 1 0 2 2 2 2 Tho1/MOS11 C-terminal domain MDMPI_C PF07398.11 EGG07453.1 - 0.12 13.3 0.9 0.74 10.7 0.1 2.4 2 1 0 2 2 2 0 MDMPI C-terminal domain PPR PF01535.20 EGG07455.1 - 0.012 15.9 0.3 54 4.4 0.0 5.1 5 1 0 5 5 5 0 PPR repeat OHCU_decarbox PF09349.10 EGG07455.1 - 0.34 11.4 3.2 1.4 9.4 0.3 2.5 2 0 0 2 2 2 0 OHCU decarboxylase Transketolase_N PF00456.21 EGG07457.1 - 2.2e-07 30.1 0.1 3e-06 26.4 0.1 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 EGG07457.1 - 0.0046 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 EGG07457.1 - 0.032 13.2 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component LAG1-DNAbind PF09271.11 EGG07458.1 - 3.9e-45 154.2 0.0 9.1e-45 153.0 0.0 1.7 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 EGG07458.1 - 1.8e-19 70.5 0.0 5.3e-16 59.2 0.0 3.0 2 1 0 2 2 2 2 Beta-trefoil DNA-binding domain TIG PF01833.24 EGG07458.1 - 0.0045 17.0 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 IPT/TIG domain DUF35_N PF12172.8 EGG07460.1 - 0.0083 16.0 0.2 0.0083 16.0 0.2 1.7 2 0 0 2 2 2 1 Rubredoxin-like zinc ribbon domain (DUF35_N) Chromo_shadow PF01393.19 EGG07460.1 - 0.086 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Chromo shadow domain FrhB_FdhB_C PF04432.13 EGG07460.1 - 0.12 12.2 0.2 0.14 11.9 0.2 1.1 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus G_glu_transpept PF01019.21 EGG07461.1 - 1.2e-147 492.8 0.0 1.4e-147 492.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Wzz PF02706.15 EGG07461.1 - 0.0093 16.3 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 Chain length determinant protein Sybindin PF04099.12 EGG07462.1 - 1.3e-19 70.6 0.0 2.8e-19 69.4 0.0 1.6 1 1 0 1 1 1 1 Sybindin-like family MFS_1 PF07690.16 EGG07463.1 - 5.6e-26 91.3 15.5 5.6e-26 91.3 15.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG07463.1 - 8.9e-06 24.8 1.7 8.9e-06 24.8 1.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EGG07463.1 - 0.00044 18.8 0.3 0.00044 18.8 0.3 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1295 PF06966.12 EGG07463.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF2431 PF10354.9 EGG07464.1 - 2.7e-40 138.4 0.0 4.3e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) SCA7 PF08313.12 EGG07465.1 - 6.7e-27 93.2 1.5 9.2e-27 92.7 0.1 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain DUF2956 PF11169.8 EGG07465.1 - 5.1 7.4 14.3 16 5.7 6.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Spc7_N PF15402.6 EGG07466.1 - 0.018 13.3 3.9 0.021 13.1 3.9 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 PLA2_B PF01735.18 EGG07467.1 - 2.8e-92 309.7 0.0 4.8e-92 308.9 0.0 1.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain DUF21 PF01595.20 EGG07469.1 - 3.9e-34 117.9 0.7 5e-34 117.5 0.7 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EGG07469.1 - 1.7e-07 31.6 0.3 0.039 14.4 0.0 2.9 3 0 0 3 3 3 2 CBS domain Vac7 PF12751.7 EGG07470.1 - 0.013 15.0 1.8 0.014 14.8 1.8 1.0 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Na_H_Exchanger PF00999.21 EGG07471.1 - 1.4e-51 175.5 28.9 1.6e-51 175.3 28.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CPP1-like PF11833.8 EGG07471.1 - 0.18 11.4 2.1 0.32 10.6 0.5 2.2 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like NMO PF03060.15 EGG07472.1 - 1.1e-30 107.2 0.8 5.9e-21 75.2 0.1 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 EGG07472.1 - 7.1e-11 41.7 0.0 1.3e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGG07472.1 - 0.039 13.0 0.2 0.074 12.1 0.2 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase SUR7 PF06687.12 EGG07473.1 - 5.2e-14 52.4 5.5 7e-14 52.0 5.5 1.2 1 0 0 1 1 1 1 SUR7/PalI family TPR_1 PF00515.28 EGG07474.1 - 4.1e-19 67.5 4.3 4.6e-07 29.4 0.3 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG07474.1 - 2.4e-16 58.4 7.0 5e-06 26.2 0.3 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGG07474.1 - 1.1e-15 56.8 1.3 0.001 19.3 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGG07474.1 - 3.4e-15 55.5 4.1 0.00011 21.8 1.4 4.5 2 2 3 5 5 5 3 TPR repeat TPR_14 PF13428.6 EGG07474.1 - 6.1e-12 45.3 2.6 0.00011 22.8 0.2 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG07474.1 - 2e-11 43.2 11.8 0.00097 19.2 0.2 5.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG07474.1 - 1.5e-09 38.4 1.2 8.9e-05 23.1 0.1 3.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG07474.1 - 2.3e-09 37.6 3.6 0.00031 21.2 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG07474.1 - 3.8e-09 36.7 6.2 3.7e-05 23.9 0.9 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG07474.1 - 2.8e-06 27.0 4.5 0.0095 15.9 0.1 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG07474.1 - 4.8e-06 26.6 0.4 0.17 12.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGG07474.1 - 7.1e-05 22.2 0.3 0.22 10.7 0.2 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGG07474.1 - 9.4e-05 22.7 0.9 1.1 9.7 0.2 3.9 2 2 3 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG07474.1 - 0.00022 21.4 0.4 0.0069 16.6 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EGG07474.1 - 0.00097 19.2 3.5 0.073 13.1 0.1 3.8 5 0 0 5 5 4 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EGG07474.1 - 0.0062 17.1 3.1 19 6.2 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGG07474.1 - 0.036 14.0 1.0 0.036 14.0 1.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGG07474.1 - 0.036 14.1 0.1 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TetR_C_19 PF17924.1 EGG07474.1 - 0.051 14.2 0.2 2.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TFIIA PF03153.13 EGG07475.1 - 2.1e-49 169.7 11.9 1.1e-31 111.2 11.8 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit ChapFlgA_N PF17656.1 EGG07475.1 - 0.028 14.6 0.1 0.055 13.6 0.1 1.5 1 0 0 1 1 1 0 FlgA N-terminal domain DUF1627 PF07789.12 EGG07475.1 - 0.2 11.3 0.7 0.31 10.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) bZIP_2 PF07716.15 EGG07476.1 - 3.1e-11 43.2 12.7 5.8e-11 42.3 12.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper XhlA PF10779.9 EGG07476.1 - 9.9e-05 22.5 4.0 0.00031 20.9 4.0 1.9 1 0 0 1 1 1 1 Haemolysin XhlA Shugoshin_N PF07558.11 EGG07476.1 - 0.00012 21.8 0.8 0.00041 20.2 0.8 2.0 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 EGG07476.1 - 0.0054 17.0 0.9 0.012 15.9 0.9 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family CCDC106 PF15794.5 EGG07476.1 - 0.011 15.4 7.9 0.011 15.4 7.9 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 Ax_dynein_light PF10211.9 EGG07476.1 - 0.024 14.6 6.8 0.041 13.8 6.8 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain bZIP_Maf PF03131.17 EGG07476.1 - 0.031 14.8 4.6 0.055 14.0 3.4 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor bZIP_1 PF00170.21 EGG07476.1 - 0.031 14.4 11.5 0.052 13.6 10.2 2.0 2 0 0 2 2 2 0 bZIP transcription factor TolA_bind_tri PF16331.5 EGG07476.1 - 0.045 13.8 1.8 0.098 12.7 1.1 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation Myb_DNA-bind_4 PF13837.6 EGG07476.1 - 0.08 13.3 3.5 0.17 12.3 3.5 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_IS240 PF13610.6 EGG07476.1 - 0.12 12.6 1.7 0.19 11.9 1.7 1.3 1 0 0 1 1 1 0 DDE domain YabA PF06156.13 EGG07476.1 - 0.16 12.6 6.7 0.39 11.4 6.7 1.8 1 1 0 1 1 1 0 Initiation control protein YabA DUF3395 PF11875.8 EGG07476.1 - 0.23 11.4 5.9 0.39 10.6 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) DUF4482 PF14818.6 EGG07476.1 - 0.31 11.9 12.4 0.15 13.0 9.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) Jnk-SapK_ap_N PF09744.9 EGG07476.1 - 0.46 10.7 13.7 0.7 10.1 13.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 PIEZO PF15917.5 EGG07476.1 - 2.7 7.4 8.0 4.1 6.8 8.0 1.2 1 0 0 1 1 1 0 Piezo CASP_C PF08172.12 EGG07476.1 - 4.1 6.7 14.4 0.15 11.3 2.8 2.3 2 0 0 2 2 2 0 CASP C terminal Phosducin PF02114.16 EGG07477.1 - 3e-12 46.1 0.0 8.8e-07 28.1 0.0 3.1 3 0 0 3 3 3 3 Phosducin MTS PF05175.14 EGG07478.1 - 2.7e-10 40.0 0.0 1.9e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 EGG07478.1 - 2.7e-08 33.8 0.0 1.6e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG07478.1 - 7e-06 26.7 0.0 3.7e-05 24.3 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGG07478.1 - 6.8e-05 22.4 0.0 0.00019 20.9 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.12 EGG07478.1 - 0.00016 21.1 0.0 0.044 13.1 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Methyltransf_12 PF08242.12 EGG07478.1 - 0.0002 22.1 0.0 0.017 15.8 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGG07478.1 - 0.00039 20.4 0.0 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG07478.1 - 0.0022 18.6 0.0 0.0095 16.6 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG07478.1 - 0.0026 17.6 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGG07478.1 - 0.0055 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.18 EGG07478.1 - 0.0095 15.6 0.0 5.7 6.6 0.0 2.5 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 AviRa PF11599.8 EGG07478.1 - 0.032 13.7 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Josephin PF02099.17 EGG07479.1 - 7.7e-43 146.4 0.1 1.5e-42 145.5 0.1 1.4 1 0 0 1 1 1 1 Josephin UIM PF02809.20 EGG07479.1 - 0.41 10.7 11.0 1.6 8.8 2.6 3.1 2 0 0 2 2 2 0 Ubiquitin interaction motif zf-SNAP50_C PF12251.8 EGG07481.1 - 2.5e-30 105.7 0.4 1.5e-29 103.1 0.4 1.8 1 1 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Smr PF01713.21 EGG07482.1 - 7.4e-10 39.1 0.3 1.1e-09 38.5 0.1 1.4 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.10 EGG07482.1 - 5.6e-09 36.2 2.9 7.6e-09 35.8 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Telomere_reg-2 PF10193.9 EGG07483.1 - 1.9e-34 118.4 0.5 4.8e-34 117.1 0.2 2.0 2 0 0 2 2 2 1 Telomere length regulation protein OxoDH_E1alpha_N PF12573.8 EGG07484.1 - 0.024 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Homeodomain PF00046.29 EGG07485.1 - 4.1e-21 74.6 3.0 4.4e-21 74.5 3.0 1.0 1 0 0 1 1 1 1 Homeodomain YdaS_antitoxin PF15943.5 EGG07485.1 - 0.021 14.7 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeobox_KN PF05920.11 EGG07485.1 - 0.037 13.9 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 EGG07485.1 - 0.083 12.4 0.2 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.22 EGG07485.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix DUF4446 PF14584.6 EGG07487.1 - 0.18 11.8 1.4 0.25 11.3 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) PUCC PF03209.15 EGG07488.1 - 0.0019 17.2 3.3 0.0029 16.7 3.3 1.2 1 0 0 1 1 1 1 PUCC protein Rhodanese PF00581.20 EGG07489.1 - 5.9e-17 62.1 0.0 7.7e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain TIM PF00121.18 EGG07490.1 - 1.7e-87 292.8 0.0 2e-87 292.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DPBB_1 PF03330.18 EGG07491.1 - 0.00088 19.5 0.0 0.0021 18.3 0.0 1.6 1 1 0 1 1 1 1 Lytic transglycolase YbjN PF10722.9 EGG07491.1 - 0.17 11.9 0.0 0.54 10.3 0.0 1.7 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator DGOK PF05035.12 EGG07491.1 - 0.18 10.6 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase PAP_central PF04928.17 EGG07492.1 - 0.063 12.3 0.0 0.21 10.6 0.0 1.8 1 1 0 1 1 1 0 Poly(A) polymerase central domain WSD PF15613.6 EGG07492.1 - 0.18 12.3 0.7 1.1 9.8 0.0 2.7 2 1 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Zip PF02535.22 EGG07493.1 - 7.3 5.7 7.2 13 4.9 7.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Mg_trans_NIPA PF05653.14 EGG07495.1 - 1.1e-95 320.1 27.3 1.5e-95 319.8 27.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EGG07495.1 - 1.7e-05 25.0 7.2 1.7e-05 25.0 7.2 4.2 3 1 0 3 3 3 2 EamA-like transporter family GNVR PF13807.6 EGG07495.1 - 1.3 9.0 3.4 1.1 9.2 0.3 2.7 2 1 1 3 3 3 0 G-rich domain on putative tyrosine kinase DUF1772 PF08592.11 EGG07495.1 - 1.6 9.0 8.0 16 5.8 3.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) tRNA-synt_2c PF01411.19 EGG07496.1 - 1.6e-210 700.3 0.0 2.1e-210 699.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EGG07496.1 - 7.3e-16 58.0 0.1 1.8e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EGG07496.1 - 2.8e-11 44.0 2.6 8.1e-11 42.5 2.6 1.8 1 0 0 1 1 1 1 DHHA1 domain DUF4083 PF13314.6 EGG07496.1 - 4.9 7.2 5.3 0.69 9.9 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) ODC_AZ PF02100.17 EGG07497.1 - 8e-12 45.2 0.0 5.7e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Ornithine decarboxylase antizyme YozE_SAM_like PF06855.12 EGG07498.1 - 0.2 11.8 0.3 0.2 11.8 0.3 2.6 3 0 0 3 3 3 0 YozE SAM-like fold Topoisom_I PF01028.20 EGG07499.1 - 7.8e-98 326.4 4.2 1.5e-97 325.4 4.2 1.5 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EGG07499.1 - 4.5e-97 323.7 0.2 4.5e-97 323.7 0.2 3.1 4 1 1 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EGG07499.1 - 5.1e-30 103.2 1.5 8.6e-30 102.5 0.3 2.1 2 0 0 2 2 2 1 C-terminal topoisomerase domain Ribosomal_S5 PF00333.20 EGG07500.1 - 1.4e-28 98.6 0.4 3.1e-28 97.6 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGG07500.1 - 9.2e-22 76.3 0.1 1.5e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EGG07500.1 - 5.7 7.6 13.0 13 6.5 13.0 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 F-box_4 PF15966.5 EGG07501.1 - 0.07 13.0 1.1 21 5.0 0.0 3.4 3 0 0 3 3 3 0 F-box F-box PF00646.33 EGG07501.1 - 1.7 8.6 7.2 1.1 9.3 0.6 2.7 2 0 0 2 2 2 0 F-box domain Myb_DNA-bind_3 PF12776.7 EGG07504.1 - 9.3e-05 23.3 0.3 0.0002 22.3 0.3 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Med14 PF08638.11 EGG07506.1 - 3.7e-55 186.3 1.0 6.9e-55 185.4 1.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 HHH PF00633.23 EGG07507.1 - 0.00039 20.1 0.0 0.001 18.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EGG07507.1 - 0.062 13.9 0.1 0.16 12.6 0.1 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix domain DMAP_binding PF06464.11 EGG07509.1 - 0.048 14.5 0.7 0.048 14.5 0.7 3.4 3 1 0 3 3 3 0 DMAP1-binding Domain DUF2439 PF10382.9 EGG07511.1 - 7.7e-24 83.8 0.1 1.3e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Glyco_hydro_92 PF07971.12 EGG07512.1 - 3.9e-96 322.8 0.7 6.9e-83 279.1 0.8 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EGG07512.1 - 2e-36 126.1 0.0 3e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain IHABP4_N PF16174.5 EGG07513.1 - 1 9.9 12.5 1.2 9.8 12.5 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF1764 PF08576.10 EGG07513.1 - 1.7 9.6 5.6 2.5 9.1 5.0 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Sec8_exocyst PF04048.14 EGG07514.1 - 6.4e-12 45.6 2.1 1.4e-10 41.3 1.7 3.1 1 1 1 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EGG07514.1 - 0.063 12.5 1.3 0.13 11.5 1.3 1.5 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex WD40_alt PF14077.6 EGG07516.1 - 1.1 9.2 3.4 4.1 7.3 1.6 2.3 2 0 0 2 2 2 0 Alternative WD40 repeat motif LSM PF01423.22 EGG07517.1 - 3.9e-19 68.1 0.1 4.8e-19 67.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain SF3b1 PF08920.10 EGG07519.1 - 3.2e-29 101.8 3.2 3.2e-29 101.8 3.2 3.0 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 EGG07519.1 - 6.1e-10 39.4 4.4 0.0017 18.7 0.1 7.3 4 2 4 8 8 8 1 HEAT repeats HEAT_EZ PF13513.6 EGG07519.1 - 4.9e-09 36.5 1.9 0.021 15.3 0.0 7.0 7 1 1 8 8 7 1 HEAT-like repeat HEAT PF02985.22 EGG07519.1 - 8.6e-07 28.7 9.7 2.1 8.8 0.0 9.1 12 0 0 12 12 8 1 HEAT repeat Cnd1 PF12717.7 EGG07519.1 - 9.2e-07 29.0 8.4 0.12 12.4 0.0 6.7 8 0 0 8 8 8 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGG07519.1 - 7.5e-06 24.8 4.9 0.053 12.1 0.1 3.4 2 1 0 3 3 3 2 Adaptin N terminal region UME PF08064.13 EGG07519.1 - 7.9e-06 25.7 0.1 0.3 11.0 0.0 5.2 4 2 2 6 6 6 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 EGG07519.1 - 1.3e-05 25.7 4.6 1 10.0 0.0 5.5 7 0 0 7 7 5 2 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 EGG07519.1 - 3.9e-05 23.4 2.4 0.9 9.2 0.0 4.4 3 1 1 4 4 4 2 NUC173 domain CLASP_N PF12348.8 EGG07519.1 - 6.5e-05 22.6 1.5 0.22 11.0 0.0 3.8 4 0 0 4 4 4 2 CLASP N terminal Dopey_N PF04118.14 EGG07519.1 - 0.0021 17.3 2.6 0.087 11.9 0.0 3.5 3 1 1 4 4 4 1 Dopey, N-terminal MMS19_C PF12460.8 EGG07519.1 - 0.0034 16.6 0.0 12 4.8 0.1 3.9 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 EGG07519.1 - 0.0077 16.2 2.2 1.1 9.1 0.3 3.9 3 2 0 3 3 3 1 Domain of unknown function (DUF3385) DNA_pol_phi PF04931.13 EGG07519.1 - 0.1 10.7 7.9 0.015 13.5 0.2 2.4 2 1 0 2 2 1 0 DNA polymerase phi YpjP PF14005.6 EGG07519.1 - 0.26 11.3 2.5 21 5.2 0.0 3.2 3 0 0 3 3 3 0 YpjP-like protein TIP120 PF08623.10 EGG07519.1 - 0.42 10.4 5.2 1.8 8.3 0.0 4.0 5 0 0 5 5 5 0 TATA-binding protein interacting (TIP20) Metallophos PF00149.28 EGG07520.1 - 4.2e-35 122.1 0.1 5.5e-35 121.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nrf1_DNA-bind PF10491.9 EGG07520.1 - 0.043 13.5 0.1 0.068 12.9 0.1 1.2 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 STPPase_N PF16891.5 EGG07520.1 - 0.12 12.8 1.8 0.29 11.6 1.8 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DLH PF01738.18 EGG07521.1 - 1.2e-22 80.6 0.0 1.5e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EGG07521.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold bacHORMA_2 PF18173.1 EGG07522.1 - 0.11 12.4 0.1 0.65 9.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial HORMA domain 2 Glyco_hydro_16 PF00722.21 EGG07523.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 PNP_UDP_1 PF01048.20 EGG07524.1 - 3.3e-09 36.3 0.0 4.1e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily AFT PF08731.11 EGG07525.1 - 0.066 13.6 1.0 0.33 11.4 0.0 2.3 2 0 0 2 2 2 0 Transcription factor AFT TFIIA PF03153.13 EGG07525.1 - 2.8 7.9 11.1 4.3 7.2 11.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec2p PF06428.11 EGG07528.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Lipase_GDSL_3 PF14606.6 EGG07529.1 - 0.085 13.0 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family PspA_IM30 PF04012.12 EGG07532.1 - 0.014 15.0 3.0 0.024 14.2 3.0 1.4 1 0 0 1 1 1 0 PspA/IM30 family Phlebovirus_NSM PF07246.11 EGG07532.1 - 0.017 14.5 1.1 0.025 14.0 0.2 1.7 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF1804 PF08822.11 EGG07532.1 - 0.47 10.4 3.0 0.27 11.2 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) COG5 PF10392.9 EGG07532.1 - 0.63 10.2 7.3 0.18 12.0 3.5 2.1 2 1 0 2 2 2 0 Golgi transport complex subunit 5 PspA_IM30 PF04012.12 EGG07533.1 - 0.0013 18.4 5.4 0.0013 18.4 5.4 2.1 2 0 0 2 2 2 1 PspA/IM30 family NPV_P10 PF05531.12 EGG07533.1 - 0.05 14.1 4.7 0.39 11.2 1.7 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ORF6C PF10552.9 EGG07533.1 - 0.12 12.5 4.8 0.32 11.1 0.1 3.2 2 1 2 4 4 4 0 ORF6C domain BLOC1_2 PF10046.9 EGG07533.1 - 2.9 8.2 13.8 1.7 9.0 2.2 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 EGG07533.1 - 5 7.8 11.4 1.1 9.9 1.2 3.8 3 1 1 4 4 4 0 SlyX Cwf_Cwc_15 PF04889.12 EGG07534.1 - 8.1 6.1 25.2 1.2 8.8 13.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Peptidase_C65 PF10275.9 EGG07536.1 - 0.016 14.7 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase C65 Otubain JAB PF01398.21 EGG07540.1 - 1.1e-05 25.4 0.1 1.4e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGG07541.1 - 1.2e-13 51.4 0.1 2e-13 50.7 0.1 1.3 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function OrsD PF12013.8 EGG07544.1 - 6.9e-14 52.3 3.3 6.9e-14 52.3 3.3 2.3 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-3CxxC_2 PF17180.4 EGG07544.1 - 0.85 10.4 5.6 12 6.7 1.2 2.9 2 0 0 2 2 2 0 Zinc-binding domain Actin_micro PF17003.5 EGG07544.1 - 1.3 8.1 8.5 1.2 8.2 0.1 2.6 2 1 0 2 2 2 0 Putative actin-like family AP3D1 PF06375.11 EGG07545.1 - 0.0033 17.7 8.9 0.0045 17.3 8.9 1.1 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 DUF4554 PF15091.6 EGG07545.1 - 0.17 10.8 2.9 0.22 10.3 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Presenilin PF01080.17 EGG07545.1 - 0.57 8.9 2.8 0.79 8.4 2.8 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGG07545.1 - 0.81 7.9 6.7 1 7.6 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein NPV_P10 PF05531.12 EGG07546.1 - 0.031 14.7 0.3 0.058 13.9 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DEAD PF00270.29 EGG07548.1 - 0.00028 20.7 0.1 0.00083 19.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase OrsD PF12013.8 EGG07548.1 - 0.0046 17.4 0.2 0.026 15.0 0.2 2.4 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D SNF2_N PF00176.23 EGG07548.1 - 0.06 12.1 0.1 0.1 11.3 0.1 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain eIF3g PF12353.8 EGG07548.1 - 0.16 12.3 1.3 0.38 11.1 1.3 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G V_ATPase_I PF01496.19 EGG07549.1 - 0.13 10.1 1.4 0.31 8.9 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CH PF00307.31 EGG07550.1 - 0.086 13.0 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Calponin homology (CH) domain DUF3139 PF11337.8 EGG07550.1 - 0.16 12.7 0.5 2.9 8.6 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) OrsD PF12013.8 EGG07551.1 - 2.4e-09 37.7 0.5 2.4e-09 37.7 0.5 3.7 4 0 0 4 4 4 1 Orsellinic acid/F9775 biosynthesis cluster protein D Helicase_C PF00271.31 EGG07552.1 - 2.7e-14 53.5 0.0 5.7e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG07552.1 - 2.8e-11 43.5 0.0 7.4e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGG07552.1 - 0.0034 17.4 0.0 0.021 14.8 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit V_ATPase_I PF01496.19 EGG07553.1 - 0.1 10.5 0.0 0.23 9.3 0.0 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SNF2_N PF00176.23 EGG07556.1 - 8e-08 31.4 0.1 9.7e-08 31.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.23 EGG07557.1 - 8.5e-07 28.0 0.1 0.0028 16.4 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain NPR3 PF03666.13 EGG07560.1 - 0.64 8.7 2.5 0.76 8.5 2.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4834 PF16118.5 EGG07560.1 - 1.5 9.8 6.3 2 9.4 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) NMT_C PF02799.15 EGG07562.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain T4SS PF07996.11 EGG07564.1 - 0.031 14.7 0.6 0.043 14.2 0.6 1.1 1 0 0 1 1 1 0 Type IV secretion system proteins CPSase_L_D2 PF02786.17 EGG07565.1 - 5.7e-22 78.3 0.0 1.3e-11 44.4 0.0 2.1 1 1 1 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EGG07565.1 - 0.0017 18.4 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Pkinase PF00069.25 EGG07566.1 - 5e-42 144.1 0.0 2.2e-14 53.4 0.0 3.0 1 1 2 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGG07566.1 - 2e-19 69.9 2.1 2.6e-07 30.2 0.0 3.1 1 1 2 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 EGG07566.1 - 0.015 14.7 2.9 0.39 10.0 2.9 3.0 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EGG07566.1 - 0.027 13.3 0.0 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGG07566.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG07566.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GCP_N_terminal PF17681.1 EGG07568.1 - 2.1e-63 214.8 0.0 6.1e-63 213.3 0.0 1.8 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGG07568.1 - 6.8e-54 183.4 13.0 6.8e-54 183.4 13.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal DUF4795 PF16043.5 EGG07568.1 - 0.28 10.7 1.5 0.58 9.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Ras PF00071.22 EGG07569.1 - 6.1e-17 61.7 0.1 6.6e-17 61.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG07569.1 - 2.3e-13 50.4 0.1 3.5e-13 49.8 0.1 1.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG07569.1 - 2.6e-05 23.8 0.0 2.7e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG07569.1 - 0.001 18.5 0.3 0.0021 17.5 0.3 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 EGG07569.1 - 0.0067 16.0 0.0 0.007 15.9 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 EGG07569.1 - 0.011 16.1 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EGG07569.1 - 0.013 15.2 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG07569.1 - 0.017 15.0 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase SRPRB PF09439.10 EGG07569.1 - 0.027 13.9 0.0 0.031 13.7 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 EGG07569.1 - 0.029 14.3 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 EGG07569.1 - 0.035 13.5 0.0 0.036 13.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 EGG07569.1 - 0.041 14.1 0.0 0.042 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 EGG07569.1 - 0.045 12.9 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 EGG07569.1 - 0.047 13.7 0.0 0.047 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGG07569.1 - 0.048 13.4 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGG07569.1 - 0.098 13.2 0.0 0.098 13.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 EGG07569.1 - 0.17 11.4 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain Herpes_UL56 PF04534.12 EGG07570.1 - 0.037 13.5 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein LSM PF01423.22 EGG07571.1 - 2e-17 62.6 0.0 2.8e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain Fungal_trans PF04082.18 EGG07572.1 - 6.9e-15 54.8 1.6 1.5e-14 53.7 1.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGG07572.1 - 2.3e-05 24.4 11.0 4.3e-05 23.5 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 EGG07572.1 - 0.21 11.4 3.9 2.3 8.0 1.4 2.7 2 0 0 2 2 2 0 Integrin plexin domain RhoGAP PF00620.27 EGG07573.1 - 1.5e-43 148.3 0.0 3e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EGG07573.1 - 9.1e-14 51.8 0.0 2.3e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PX PF00787.24 EGG07573.1 - 7e-08 32.5 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 PX domain PH_11 PF15413.6 EGG07573.1 - 0.0027 18.1 0.0 0.0097 16.3 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Protoglobin PF11563.8 EGG07573.1 - 0.027 14.4 0.1 0.056 13.4 0.1 1.4 1 0 0 1 1 1 0 Protoglobin PH_8 PF15409.6 EGG07573.1 - 0.18 12.1 0.0 0.87 9.9 0.0 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Arm-DNA-bind_3 PF13356.6 EGG07574.1 - 0.066 13.6 0.3 1.4 9.4 0.2 2.4 2 0 0 2 2 2 0 Arm DNA-binding domain Alpha_kinase PF02816.18 EGG07577.1 - 3.8e-10 40.2 0.9 4.7e-10 39.9 0.9 1.1 1 0 0 1 1 1 1 Alpha-kinase family zf-CCHC_2 PF13696.6 EGG07578.1 - 0.014 15.2 2.9 0.039 13.8 2.9 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EGG07578.1 - 3.1 8.0 10.5 0.42 10.8 1.8 2.5 2 0 0 2 2 2 0 Zinc knuckle FGGY_C PF02782.16 EGG07580.1 - 1e-59 201.6 0.2 2.3e-59 200.5 0.2 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGG07580.1 - 1.7e-59 201.4 0.0 2.7e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain RNA_pol_Rpb1_1 PF04997.12 EGG07581.1 - 1.1e-80 271.4 0.4 1.5e-79 267.6 0.4 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EGG07581.1 - 2.9e-79 266.2 0.3 4.9e-79 265.5 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGG07581.1 - 3e-71 239.0 0.0 5.7e-71 238.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGG07581.1 - 3.8e-38 130.9 0.0 9.6e-38 129.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGG07581.1 - 3e-30 104.4 0.0 8.8e-30 102.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF1178 PF06676.11 EGG07581.1 - 0.14 12.5 0.2 0.3 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Na_Ca_ex PF01699.24 EGG07582.1 - 6.3e-20 71.7 35.3 6.5e-14 52.1 13.1 4.0 4 2 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 EGG07582.1 - 3.4e-13 50.1 8.7 3.4e-13 50.1 8.7 4.7 3 1 0 3 3 3 1 Inner membrane component domain Zn_Tnp_IS1595 PF12760.7 EGG07582.1 - 0.13 12.2 0.5 0.26 11.3 0.5 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF4379 PF14311.6 EGG07582.1 - 0.14 12.6 0.1 0.33 11.3 0.1 1.6 1 0 0 1 1 1 0 Probable Zinc-ribbon domain PRK PF00485.18 EGG07583.1 - 4.6e-11 42.8 0.0 6.4e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 EGG07583.1 - 0.00016 21.9 0.0 0.00032 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG07583.1 - 0.0002 21.9 0.3 0.0018 18.8 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG07583.1 - 0.00072 20.0 0.1 0.00092 19.6 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 EGG07583.1 - 0.0017 18.3 0.1 0.0026 17.7 0.1 1.2 1 0 0 1 1 1 1 NTPase AAA_30 PF13604.6 EGG07583.1 - 0.0055 16.4 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGG07583.1 - 0.0063 15.7 0.0 0.014 14.6 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 EGG07583.1 - 0.0074 16.5 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain CoaE PF01121.20 EGG07583.1 - 0.0075 16.0 0.1 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_5 PF07728.14 EGG07583.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EGG07583.1 - 0.027 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 EGG07583.1 - 0.04 13.2 0.0 0.096 11.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 EGG07583.1 - 0.044 14.3 0.1 0.08 13.5 0.1 1.4 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 EGG07583.1 - 0.046 13.6 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 EGG07583.1 - 0.046 14.1 0.0 1 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGG07583.1 - 0.052 12.8 0.0 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 EGG07583.1 - 0.06 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 EGG07583.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGG07583.1 - 0.089 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 EGG07583.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 EGG07583.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGG07583.1 - 0.16 12.2 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EGG07583.1 - 0.17 11.1 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.6 EGG07583.1 - 0.17 12.3 0.1 0.36 11.3 0.1 1.5 2 0 0 2 2 1 0 AAA domain DUF87 PF01935.17 EGG07583.1 - 0.19 11.8 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 EGG07583.1 - 0.19 11.4 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 EGG07583.1 - 0.23 11.3 0.1 0.58 10.0 0.0 1.6 2 0 0 2 2 2 0 Deoxynucleoside kinase Asp PF00026.23 EGG07584.1 - 2.9e-15 56.5 0.0 1.5e-14 54.2 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Taxilin PF09728.9 EGG07585.1 - 0.0019 17.4 2.3 0.0019 17.4 2.3 1.9 2 0 0 2 2 2 1 Myosin-like coiled-coil protein 4HB_MCP_1 PF12729.7 EGG07585.1 - 0.02 14.5 0.9 0.02 14.5 0.9 2.3 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction BMFP PF04380.13 EGG07585.1 - 0.026 15.0 6.5 0.1 13.1 1.1 4.0 1 1 1 3 3 3 0 Membrane fusogenic activity LPP PF04728.13 EGG07585.1 - 0.043 14.2 4.1 4.9 7.6 0.2 3.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper PKcGMP_CC PF16808.5 EGG07585.1 - 0.12 12.2 3.5 3.8 7.5 0.2 2.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HAUS-augmin3 PF14932.6 EGG07585.1 - 0.17 11.5 6.1 0.085 12.4 2.3 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Tropomyosin PF00261.20 EGG07585.1 - 0.18 11.2 9.5 0.15 11.4 5.6 2.2 2 0 0 2 2 2 0 Tropomyosin Pil1 PF13805.6 EGG07585.1 - 0.29 10.6 15.4 0.27 10.7 0.6 3.5 2 1 1 4 4 4 0 Eisosome component PIL1 DUF2730 PF10805.8 EGG07585.1 - 0.32 11.1 7.6 10 6.3 2.5 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2730) LcrG PF07216.12 EGG07585.1 - 0.43 10.5 3.4 4.6 7.2 0.0 3.2 2 1 0 3 3 3 0 LcrG protein TSC22 PF01166.18 EGG07585.1 - 0.87 9.9 7.1 9 6.7 0.1 4.0 3 1 1 4 4 4 0 TSC-22/dip/bun family CtIP_N PF10482.9 EGG07585.1 - 1 9.4 11.2 0.33 11.0 6.8 2.4 2 2 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Prefoldin_2 PF01920.20 EGG07585.1 - 1.6 8.7 10.3 0.12 12.3 1.2 3.6 2 2 1 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.8 EGG07585.1 - 2.7 8.1 10.1 12 6.0 0.6 3.1 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding GlutR_dimer PF00745.20 EGG07585.1 - 2.9 8.4 9.7 23 5.5 0.1 3.7 2 1 2 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain TMPIT PF07851.13 EGG07585.1 - 3.1 6.9 7.3 1.8 7.7 3.1 2.3 2 1 0 2 2 2 0 TMPIT-like protein Swi5 PF07061.11 EGG07585.1 - 4.8 7.3 9.2 9.1 6.5 1.8 3.5 3 1 0 3 3 3 0 Swi5 DUF4140 PF13600.6 EGG07585.1 - 6.6 7.2 10.0 1.6 9.2 2.7 3.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF92 PF01940.16 EGG07586.1 - 6.7e-61 205.7 1.5 7.7e-61 205.5 1.5 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 SUR7 PF06687.12 EGG07587.1 - 2.4e-06 27.3 1.3 2.4e-06 27.3 1.3 1.6 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 EGG07587.1 - 0.0078 16.0 6.1 0.14 11.9 0.2 2.4 2 1 1 3 3 3 2 PMP-22/EMP/MP20/Claudin tight junction GPI-anchored PF10342.9 EGG07588.1 - 3.4e-09 37.3 0.0 9.6e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GCM PF03615.15 EGG07589.1 - 0.18 11.7 1.4 0.41 10.5 0.2 2.2 2 0 0 2 2 2 0 GCM motif protein GPI-anchored PF10342.9 EGG07590.1 - 4.2e-13 49.9 0.6 4.2e-13 49.9 0.6 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FSA_C PF10479.9 EGG07590.1 - 0.15 10.2 14.6 0.18 9.9 14.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus HhH-GPD PF00730.25 EGG07592.1 - 1.8e-11 44.5 0.0 3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Spc7_N PF15402.6 EGG07592.1 - 4.2 5.5 7.6 7 4.8 7.6 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 CN_hydrolase PF00795.22 EGG07593.1 - 6.2e-50 169.9 0.0 6.7e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Patatin PF01734.22 EGG07594.1 - 7.8e-10 39.3 0.6 9.1e-10 39.1 0.6 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase TRI9 PF08195.11 EGG07596.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 TRI9 protein Keratin_B2 PF01500.17 EGG07596.1 - 5.8 6.9 6.6 0.7 9.9 1.3 2.1 3 0 0 3 3 3 0 Keratin, high sulfur B2 protein VWA PF00092.28 EGG07598.1 - 4.6e-10 40.0 0.0 1.4e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGG07598.1 - 1.3e-08 35.4 0.0 3.2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.8 EGG07598.1 - 0.0029 17.5 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A PTPRCAP PF15713.5 EGG07598.1 - 0.44 10.8 8.6 2.1 8.6 8.0 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Myc_N PF01056.18 EGG07598.1 - 0.51 10.2 9.6 1.2 9.0 9.6 1.6 1 1 0 1 1 1 0 Myc amino-terminal region DUF4637 PF15470.6 EGG07598.1 - 1.8 8.3 6.2 2.9 7.6 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CxC5 PF18718.1 EGG07599.1 - 1.6e-28 99.1 8.3 2.4e-28 98.5 8.3 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Transp_cyt_pur PF02133.15 EGG07599.1 - 0.11 11.3 0.1 0.19 10.5 0.1 1.3 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3759 PF12585.8 EGG07602.1 - 1.1e-28 99.1 1.3 1.3e-28 98.9 1.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3759) DUF2939 PF11159.8 EGG07602.1 - 0.08 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) UbiA PF01040.18 EGG07603.1 - 1e-49 169.2 14.7 1.3e-49 168.8 14.7 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3431 PF11913.8 EGG07605.1 - 0.004 17.0 0.1 0.011 15.5 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Ras PF00071.22 EGG07607.1 - 6.7e-54 181.8 0.0 8e-54 181.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG07607.1 - 5.4e-22 78.2 0.0 8.1e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG07607.1 - 1.8e-09 37.3 0.0 2.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DLIC PF05783.11 EGG07607.1 - 0.015 14.1 0.0 0.053 12.4 0.0 1.7 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) Gtr1_RagA PF04670.12 EGG07607.1 - 0.026 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGG07607.1 - 0.031 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGG07607.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 EGG07607.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 EGG07607.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 EGG07607.1 - 0.12 11.5 0.0 0.25 10.4 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit Sas10 PF09368.10 EGG07609.1 - 2.9e-26 91.7 8.8 2.9e-26 91.7 8.8 3.0 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EGG07609.1 - 0.07 13.8 0.1 0.07 13.8 0.1 3.8 4 1 0 4 4 4 0 Sas10/Utp3/C1D family G-patch PF01585.23 EGG07611.1 - 8.7e-08 31.9 2.5 8.7e-08 31.9 2.5 3.1 3 0 0 3 3 3 1 G-patch domain zf-C2H2_jaz PF12171.8 EGG07611.1 - 1.2e-05 25.4 3.1 2.4e-05 24.5 3.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG07611.1 - 0.00015 22.0 0.9 0.00027 21.2 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.7 EGG07611.1 - 0.0018 18.3 1.3 0.0018 18.3 1.3 2.9 2 1 0 2 2 2 1 G-patch domain zf-C2H2 PF00096.26 EGG07611.1 - 0.02 15.3 1.1 0.045 14.2 1.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type ATG2_CAD PF13329.6 EGG07611.1 - 0.083 12.6 5.9 8.2 6.1 0.1 3.4 3 0 0 3 3 3 0 Autophagy-related protein 2 CAD motif EIIBC-GUT_N PF03612.14 EGG07611.1 - 0.73 9.6 11.5 0.24 11.1 0.7 2.7 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Trehalase PF01204.18 EGG07612.1 - 7.4e-96 322.0 0.7 1.1e-95 321.5 0.7 1.3 1 0 0 1 1 1 1 Trehalase Lipoprotein_6 PF01441.19 EGG07612.1 - 1.1 9.3 7.2 1.7 8.6 0.2 2.6 3 0 0 3 3 3 0 Lipoprotein DDHD PF02862.17 EGG07613.1 - 0.14 12.2 5.6 0.24 11.5 5.6 1.4 1 0 0 1 1 1 0 DDHD domain DUF966 PF06136.13 EGG07613.1 - 0.88 9.2 19.5 1.2 8.7 19.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) ORC6 PF05460.13 EGG07613.1 - 1.1 8.4 15.1 1.8 7.8 15.1 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PPL5 PF18168.1 EGG07613.1 - 2.2 7.5 10.4 3.7 6.8 10.4 1.3 1 0 0 1 1 1 0 Prim-pol family 5 DUF4045 PF13254.6 EGG07613.1 - 2.3 7.8 24.0 4.4 6.8 24.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Endostatin PF06482.11 EGG07613.1 - 2.4 7.6 7.7 4.2 6.7 7.7 1.5 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF2828 PF11443.8 EGG07613.1 - 3.3 5.7 13.3 4.8 5.2 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) eIF3_p135 PF12807.7 EGG07613.1 - 3.9 7.5 7.7 3.4 7.7 6.4 1.5 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 DUF4770 PF15994.5 EGG07613.1 - 4.3 7.5 11.0 7.7 6.7 11.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Neur_chan_memb PF02932.16 EGG07613.1 - 5 7.1 6.7 7.6 6.5 6.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NARP1 PF12569.8 EGG07613.1 - 7.3 5.4 19.3 10 4.9 19.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Paramyxo_ncap PF00973.19 EGG07613.1 - 8.1 5.2 14.1 11 4.8 14.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Connexin PF00029.19 EGG07613.1 - 8.5 6.1 12.3 14 5.4 12.3 1.4 1 0 0 1 1 1 0 Connexin Peptidase_S64 PF08192.11 EGG07613.1 - 9.4 4.6 12.3 13 4.1 12.3 1.3 1 0 0 1 1 1 0 Peptidase family S64 CRAL_TRIO PF00650.20 EGG07614.1 - 7.4e-19 68.0 0.0 2e-18 66.6 0.0 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGG07614.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF3439 PF11921.8 EGG07614.1 - 2.1 8.3 4.8 4.4 7.3 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CRAL_TRIO PF00650.20 EGG07616.1 - 9.4e-19 67.7 0.0 2.4e-18 66.4 0.0 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGG07616.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF3439 PF11921.8 EGG07616.1 - 2.3 8.2 4.8 5 7.1 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CTK3 PF12243.8 EGG07617.1 - 4e-27 94.6 0.8 5.8e-25 87.7 0.8 2.3 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EGG07617.1 - 4.2e-13 49.3 0.0 1.3e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus FACT-Spt16_Nlob PF14826.6 EGG07618.1 - 0.059 13.2 0.3 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain Macoilin PF09726.9 EGG07618.1 - 0.069 11.7 2.2 0.091 11.3 2.2 1.1 1 0 0 1 1 1 0 Macoilin family S36_mt PF10937.8 EGG07618.1 - 0.46 12.1 5.0 0.25 13.0 1.2 2.3 1 1 1 2 2 2 0 Ribosomal protein S36, mitochondrial Med13_C PF06333.12 EGG07618.1 - 4.2 6.5 16.0 6.8 5.9 16.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DUF2981 PF11200.8 EGG07618.1 - 5.1 6.7 8.0 8.4 6.0 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SOG2 PF10428.9 EGG07618.1 - 7.5 5.6 15.8 10 5.2 15.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2671 PF10877.8 EGG07619.1 - 0.13 12.0 0.6 0.31 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2671) Myb_DNA-binding PF00249.31 EGG07622.1 - 0.013 15.7 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain FancD2 PF14631.6 EGG07622.1 - 0.24 8.8 4.4 0.35 8.2 4.4 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease OAD_gamma PF04277.13 EGG07623.1 - 0.0037 17.8 3.0 5.2 7.7 0.0 4.0 4 0 0 4 4 4 2 Oxaloacetate decarboxylase, gamma chain Sugar_tr PF00083.24 EGG07623.1 - 0.0076 15.2 2.2 0.0076 15.2 2.2 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter DUF3989 PF13150.6 EGG07623.1 - 0.027 14.2 0.2 0.075 12.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Pex14_N PF04695.13 EGG07623.1 - 0.13 12.9 0.0 0.13 12.9 0.0 2.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SRAP PF02586.14 EGG07624.1 - 6.5e-74 248.2 0.1 8.1e-74 247.8 0.1 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Ala_racemase_N PF01168.20 EGG07625.1 - 2.7e-17 63.1 0.0 3.4e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HsbA PF12296.8 EGG07627.1 - 0.071 13.5 0.2 0.13 12.7 0.2 1.3 1 0 0 1 1 1 0 Hydrophobic surface binding protein A RasGEF PF00617.19 EGG07628.1 - 1.1e-49 169.1 0.0 2.3e-49 168.0 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGG07628.1 - 4.8e-21 75.0 0.0 1.4e-20 73.5 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 EGG07628.1 - 3.1e-07 30.2 0.0 6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGG07628.1 - 5e-07 29.3 0.0 8.8e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGG07628.1 - 2.7e-05 23.7 0.0 6.1e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PH_BEACH PF14844.6 EGG07628.1 - 0.14 12.3 0.1 0.36 10.9 0.1 1.7 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH Nop14 PF04147.12 EGG07629.1 - 1.1e-06 27.3 36.9 1.8e-06 26.5 36.9 1.4 1 0 0 1 1 1 1 Nop14-like family Nbl1_Borealin_N PF10444.9 EGG07629.1 - 0.00018 21.1 0.7 0.00076 19.1 0.7 2.2 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Borealin PF10512.9 EGG07629.1 - 0.00036 20.5 0.1 0.00074 19.5 0.1 1.5 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 Raftlin PF15250.6 EGG07629.1 - 0.11 11.2 15.2 0.21 10.3 15.2 1.4 1 0 0 1 1 1 0 Raftlin SDA1 PF05285.12 EGG07629.1 - 0.53 9.7 51.7 0.059 12.8 47.5 1.5 2 0 0 2 2 2 0 SDA1 CDC27 PF09507.10 EGG07629.1 - 4 6.7 41.8 1.6 8.0 36.0 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 POP1 PF06978.11 EGG07630.1 - 7.8e-45 153.4 22.2 9.9e-23 81.2 4.7 2.7 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EGG07630.1 - 6e-18 65.0 0.7 1.9e-17 63.4 0.7 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 EGG07630.1 - 0.0096 15.3 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain SPOB_a PF14689.6 EGG07631.1 - 0.1 12.3 0.1 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain Retrotran_gag_2 PF14223.6 EGG07633.1 - 0.00095 18.8 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Mer2 PF09074.10 EGG07633.1 - 0.031 14.1 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Mer2 DUF3040 PF11239.8 EGG07634.1 - 0.19 12.0 0.1 0.41 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF4451 PF14616.6 EGG07636.1 - 1.8e-16 60.4 3.3 4.9e-16 59.0 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) DUF3328 PF11807.8 EGG07637.1 - 0.00099 18.9 0.1 0.0011 18.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Vpu PF00558.19 EGG07637.1 - 0.1 12.4 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 Vpu protein Sigma_reg_N PF13800.6 EGG07637.1 - 0.16 12.3 0.1 0.29 11.5 0.1 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Shikimate_dh_N PF08501.11 EGG07639.1 - 9.5e-17 61.0 0.0 1.8e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DUF717 PF05338.12 EGG07639.1 - 0.046 13.8 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF717) NUC153 PF08159.12 EGG07640.1 - 0.38 10.6 4.8 11 5.9 0.3 2.8 2 0 0 2 2 2 0 NUC153 domain TauD PF02668.16 EGG07641.1 - 2.6e-39 135.6 0.1 3.3e-39 135.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Herpes_DNAp_acc PF04929.12 EGG07644.1 - 0.63 9.0 14.2 0.8 8.6 14.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2992 PF11208.8 EGG07644.1 - 3.8 7.7 10.3 8.7 6.6 6.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2992) GCM PF03615.15 EGG07645.1 - 6.2 6.7 9.3 2.3 8.1 5.3 2.3 2 1 0 2 2 2 0 GCM motif protein GIT1_C PF12205.8 EGG07646.1 - 0.02 15.0 1.3 0.072 13.2 0.0 2.3 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term SCP2 PF02036.17 EGG07647.1 - 8e-27 93.7 2.2 1.1e-26 93.3 2.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EGG07647.1 - 0.0053 17.0 0.1 0.0066 16.7 0.1 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Myb_DNA-bind_3 PF12776.7 EGG07648.1 - 2.9e-07 31.4 1.7 8e-07 30.0 1.7 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Dynamin_N PF00350.23 EGG07652.1 - 4.4e-18 65.9 0.2 9.4e-18 64.8 0.2 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGG07652.1 - 1.5e-10 41.2 0.1 1.2e-09 38.3 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG07652.1 - 3.3e-07 30.0 0.4 3.7e-06 26.6 0.4 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 EGG07652.1 - 0.00012 21.7 0.1 0.0024 17.5 0.1 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EGG07652.1 - 0.00048 20.1 0.2 0.95 9.3 0.0 2.7 2 1 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGG07652.1 - 0.03 14.1 0.0 0.08 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 EGG07652.1 - 0.087 11.9 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Arf PF00025.21 EGG07652.1 - 0.091 12.2 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family TsaE PF02367.17 EGG07652.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIN_8 PF18476.1 EGG07652.1 - 0.12 12.3 0.4 2.3 8.0 0.1 2.7 3 0 0 3 3 3 0 PIN like domain DUF3883 PF13020.6 EGG07652.1 - 0.14 12.2 0.2 0.54 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3883) His_Phos_1 PF00300.22 EGG07653.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) ANAPC2 PF08672.11 EGG07653.1 - 0.065 13.7 1.2 0.065 13.7 1.2 3.6 5 1 0 5 5 5 0 Anaphase promoting complex (APC) subunit 2 DUF3349 PF11829.8 EGG07653.1 - 0.076 13.8 1.6 0.34 11.7 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) Pro_sub2 PF18513.1 EGG07653.1 - 0.48 10.6 5.2 0.43 10.8 0.3 3.1 2 2 1 3 3 3 0 Prodomain subtilisin 2 RALF PF05498.11 EGG07654.1 - 8.1e-17 62.0 2.2 8.5e-17 61.9 2.2 1.0 1 0 0 1 1 1 1 Rapid ALkalinization Factor (RALF) MA3 PF02847.17 EGG07655.1 - 0.14 12.1 0.5 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 MA3 domain LOR PF04525.12 EGG07656.1 - 0.012 15.2 0.0 0.071 12.7 0.0 1.9 2 0 0 2 2 2 0 LURP-one-related Inhibitor_I66 PF16850.5 EGG07656.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I66 Ribosomal_L10 PF00466.20 EGG07657.1 - 0.00055 20.0 0.1 0.0015 18.6 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L10 Med25 PF11232.8 EGG07657.1 - 0.026 14.5 0.2 0.058 13.4 0.2 1.6 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 ESCRT-II PF05871.12 EGG07658.1 - 1.2e-25 90.4 2.0 3.9e-25 88.7 2.0 1.8 1 1 0 1 1 1 1 ESCRT-II complex subunit Herpes_UL36 PF03586.13 EGG07662.1 - 0.023 14.0 0.7 0.03 13.7 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Arc PF03869.14 EGG07662.1 - 0.1 12.5 0.2 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Arc-like DNA binding domain Glyco_hydro_71 PF03659.14 EGG07663.1 - 4e-93 312.2 0.2 5e-93 311.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF5305 PF17231.2 EGG07663.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DevR PF01905.16 EGG07664.1 - 0.013 14.6 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 HSBP1 PF06825.12 EGG07664.1 - 0.39 10.6 1.5 0.55 10.1 0.3 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Syntaxin-6_N PF09177.11 EGG07664.1 - 1.1 9.8 4.1 6.7 7.3 0.1 2.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal WD40 PF00400.32 EGG07665.1 - 3.3e-42 141.6 21.2 1.2e-08 35.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG07665.1 - 4.8e-09 36.4 0.6 0.15 12.4 0.0 4.8 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG07665.1 - 0.00098 17.9 4.8 0.31 9.6 0.2 3.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 EGG07665.1 - 0.023 13.8 0.0 0.99 8.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) WD40_like PF17005.5 EGG07665.1 - 0.14 11.5 0.0 3.1 7.0 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Lipase_GDSL PF00657.22 EGG07666.1 - 3.3e-05 23.9 0.0 3.8e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-C2H2 PF00096.26 EGG07668.1 - 1.4e-07 31.6 7.8 0.00051 20.3 0.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG07668.1 - 0.00048 20.4 2.0 0.00048 20.4 2.0 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG07668.1 - 0.026 15.3 6.4 3.5 8.7 1.6 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 EGG07668.1 - 0.21 12.2 1.7 1.7 9.3 1.7 2.4 1 1 0 1 1 1 0 FOXP coiled-coil domain DPBB_1 PF03330.18 EGG07670.1 - 0.0003 21.0 0.0 0.0005 20.3 0.0 1.5 1 1 0 1 1 1 1 Lytic transglycolase RRM_1 PF00076.22 EGG07671.1 - 1.1e-22 79.6 0.0 1.4e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG07671.1 - 0.0016 18.6 0.0 0.0026 17.8 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 EGG07671.1 - 0.013 15.6 0.1 0.021 14.9 0.1 1.4 1 1 0 1 1 1 0 Limkain b1 DUF3343 PF11823.8 EGG07671.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) RRM_3 PF08777.11 EGG07671.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif EcsC PF12787.7 EGG07671.1 - 0.16 11.6 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 EcsC protein family RRM_5 PF13893.6 EGG07671.1 - 0.17 11.5 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RasGAP PF00616.19 EGG07674.1 - 2e-57 194.3 0.2 6.5e-57 192.6 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGG07674.1 - 2.2e-33 115.3 0.5 1.1e-32 113.1 0.0 2.4 2 0 0 2 2 2 1 RasGAP C-terminus Asparaginase_2 PF01112.18 EGG07674.1 - 0.16 10.9 0.0 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Asparaginase SlyX PF04102.12 EGG07674.1 - 4.4 8.0 8.1 4.7 7.9 3.7 3.3 3 0 0 3 3 3 0 SlyX TPR_1 PF00515.28 EGG07675.1 - 1.6e-20 72.0 13.9 0.00012 21.8 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGG07675.1 - 1.7e-17 62.1 7.8 4.2e-05 23.4 0.1 6.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG07675.1 - 7e-17 60.1 19.0 0.00013 21.8 0.0 7.6 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGG07675.1 - 1.1e-16 60.2 6.4 3.5e-06 26.6 0.8 3.9 2 1 1 3 3 3 3 TPR repeat TPR_14 PF13428.6 EGG07675.1 - 1.2e-14 53.8 12.1 0.0019 18.8 0.0 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG07675.1 - 8.6e-13 48.6 7.0 0.0011 19.4 0.4 6.9 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG07675.1 - 5.7e-11 42.9 6.3 0.0001 22.9 0.2 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG07675.1 - 1e-09 38.1 5.1 0.053 13.9 0.1 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG07675.1 - 1.8e-08 34.5 14.9 0.075 13.3 0.1 5.8 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGG07675.1 - 4.4e-07 29.5 9.9 0.055 13.5 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC8 PF04049.13 EGG07675.1 - 2.6e-06 27.5 0.0 5.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_9 PF13371.6 EGG07675.1 - 5.6e-06 26.4 1.3 0.15 12.3 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGG07675.1 - 2.2e-05 23.8 11.1 0.00029 20.1 6.7 3.1 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGG07675.1 - 0.01 16.4 0.4 22 6.1 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG07675.1 - 0.019 15.2 6.8 5.8 7.2 0.7 4.5 2 1 4 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 EGG07675.1 - 0.021 13.8 0.1 3.6 6.5 0.0 2.5 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3808 PF10300.9 EGG07675.1 - 0.036 12.8 0.0 0.069 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_10 PF13374.6 EGG07675.1 - 0.039 13.8 4.3 29 4.7 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 EGG07675.1 - 0.1 12.6 0.4 0.6 10.2 0.2 2.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_MalT PF17874.1 EGG07675.1 - 0.13 11.6 2.1 0.34 10.2 0.7 2.2 1 1 0 2 2 2 0 MalT-like TPR region Prok-TraM PF09228.10 EGG07675.1 - 0.14 12.5 0.4 3.4 8.1 0.2 2.6 1 1 1 2 2 2 0 Prokaryotic Transcriptional repressor TraM TPR_6 PF13174.6 EGG07675.1 - 0.16 12.7 16.2 54 4.7 0.0 7.6 7 1 0 7 7 7 0 Tetratricopeptide repeat TadE PF07811.12 EGG07677.1 - 1.3 9.3 4.1 4.8 7.5 1.0 2.8 2 0 0 2 2 2 0 TadE-like protein Ribosomal_S21 PF01165.20 EGG07679.1 - 6.5e-11 41.8 4.3 9.4e-11 41.3 4.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S21 MBOAT_2 PF13813.6 EGG07680.1 - 2.2e-13 50.3 0.6 5.2e-13 49.1 0.6 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family zf-DNL PF05180.12 EGG07681.1 - 1.4e-27 95.4 1.0 2e-27 94.9 1.0 1.3 1 0 0 1 1 1 1 DNL zinc finger HMG_box PF00505.19 EGG07684.1 - 0.02 15.3 1.4 1.2 9.6 0.1 2.6 2 0 0 2 2 2 0 HMG (high mobility group) box Rx_N PF18052.1 EGG07684.1 - 0.035 14.4 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 Rx N-terminal domain GREB1 PF15782.5 EGG07684.1 - 1.5 5.8 11.6 1.9 5.5 11.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BUD22 PF09073.10 EGG07684.1 - 4.4 6.5 35.8 0.16 11.2 26.9 2.5 2 1 1 3 3 3 0 BUD22 DUF953 PF06110.11 EGG07685.1 - 5.6e-19 67.9 0.0 6.7e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_8 PF13905.6 EGG07685.1 - 0.0049 17.2 0.3 0.013 15.8 0.2 1.7 1 1 1 2 2 2 1 Thioredoxin-like ILEI PF15711.5 EGG07685.1 - 0.02 15.4 0.1 0.039 14.4 0.1 1.5 1 0 0 1 1 1 0 Interleukin-like EMT inducer Epsilon_antitox PF08998.11 EGG07685.1 - 0.079 13.2 1.2 0.083 13.2 0.2 1.5 2 0 0 2 2 2 0 Bacterial epsilon antitoxin Alpha_kinase PF02816.18 EGG07686.1 - 4.5e-10 40.0 0.0 9.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Alpha-kinase family DUF4106 PF13388.6 EGG07686.1 - 0.29 10.3 2.5 0.51 9.5 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF1027 PF06265.11 EGG07687.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) DUF3394 PF11874.8 EGG07688.1 - 0.14 11.8 2.0 0.24 11.1 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Pantoate_ligase PF02569.15 EGG07689.1 - 7.4e-47 159.8 0.0 8.3e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase UCH PF00443.29 EGG07690.1 - 4.4e-52 177.1 0.0 1.2e-51 175.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG07690.1 - 4.1e-25 89.0 9.2 7.5e-20 71.7 0.1 3.0 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EGG07690.1 - 0.0067 15.9 2.0 0.0067 15.9 2.0 2.9 4 0 0 4 4 4 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Myb_DNA-bind_7 PF15963.5 EGG07690.1 - 1.1 9.2 4.0 2.6 8.0 4.0 1.6 1 0 0 1 1 1 0 Myb DNA-binding like Bromodomain PF00439.25 EGG07692.1 - 1.4e-36 124.4 2.1 2.2e-19 69.3 0.5 2.4 2 0 0 2 2 2 2 Bromodomain CxC5 PF18718.1 EGG07694.1 - 2.4e-30 105.0 6.5 5.6e-30 103.8 6.5 1.7 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG07694.1 - 3.4e-10 40.0 0.0 3.4e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 EGG07694.1 - 0.03 14.2 0.1 0.089 12.6 0.1 1.8 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases RRS1 PF04939.12 EGG07695.1 - 3.8e-57 192.7 2.3 3.8e-57 192.7 2.3 2.3 3 0 0 3 3 3 1 Ribosome biogenesis regulatory protein (RRS1) IncFII_repA PF02387.15 EGG07695.1 - 0.61 9.3 8.1 0.99 8.6 8.1 1.2 1 0 0 1 1 1 0 IncFII RepA protein family DUF572 PF04502.13 EGG07695.1 - 4.4 6.8 20.3 5.9 6.4 20.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Prok-RING_1 PF14446.6 EGG07696.1 - 0.081 12.9 2.8 0.25 11.3 2.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 CARD_2 PF16739.5 EGG07696.1 - 0.093 12.7 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Caspase recruitment domain DUF1835 PF08874.10 EGG07696.1 - 0.11 12.8 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) CARD_2 PF16739.5 EGG07697.1 - 0.027 14.5 0.3 0.071 13.1 0.0 1.8 2 0 0 2 2 2 0 Caspase recruitment domain DNA_pol3_alpha PF07733.12 EGG07697.1 - 0.031 13.9 0.2 0.45 10.1 0.0 2.4 3 0 0 3 3 3 0 Bacterial DNA polymerase III alpha NTPase domain USP8_dimer PF08969.11 EGG07697.1 - 0.055 13.7 0.7 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 USP8 dimerisation domain DNA_pol3_alpha PF07733.12 EGG07700.1 - 0.014 15.0 0.3 0.051 13.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial DNA polymerase III alpha NTPase domain zf-RING_2 PF13639.6 EGG07701.1 - 3.1e-06 27.4 4.5 6.9e-06 26.3 4.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGG07701.1 - 0.00021 21.1 4.2 0.00065 19.5 4.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EGG07701.1 - 0.00093 18.9 3.0 0.002 17.8 3.0 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGG07701.1 - 0.0039 17.5 4.1 0.012 15.9 4.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 EGG07701.1 - 0.0047 16.9 1.0 0.0084 16.1 0.3 1.9 2 1 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 EGG07701.1 - 0.0094 16.0 2.8 0.024 14.7 2.8 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 EGG07701.1 - 0.011 15.6 8.1 0.018 14.9 2.4 2.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4 PF00097.25 EGG07701.1 - 0.052 13.4 4.2 0.14 12.1 4.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG07701.1 - 0.096 12.6 3.7 0.6 10.0 3.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGG07701.1 - 0.46 10.4 7.8 0.61 10.0 6.3 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EGG07701.1 - 5 7.5 6.4 3.6 8.0 4.1 2.1 2 1 0 2 2 2 0 RING-like domain Cpn60_TCP1 PF00118.24 EGG07703.1 - 9.6e-167 555.5 1.3 1.1e-166 555.3 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MBOAT_2 PF13813.6 EGG07704.1 - 1.9e-11 44.1 0.8 4.3e-11 42.9 0.8 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Glyco_hydro_39 PF01229.17 EGG07704.1 - 0.036 12.7 0.0 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 DUF4235 PF14019.6 EGG07704.1 - 0.087 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) MBOAT_2 PF13813.6 EGG07705.1 - 1.3e-12 47.8 1.6 2.9e-12 46.7 1.6 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.6 EGG07706.1 - 2e-07 31.2 0.1 4.3e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Chitin_synth_2 PF03142.15 EGG07707.1 - 2.3e-238 792.1 0.7 3e-238 791.7 0.7 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EGG07707.1 - 1.4e-100 337.5 0.0 7.3e-100 335.1 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 EGG07707.1 - 1e-17 63.8 0.1 5.1e-17 61.5 0.0 2.3 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 EGG07707.1 - 1.4e-14 53.9 0.2 7.7e-10 38.8 0.0 3.4 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 EGG07707.1 - 2.4e-11 43.9 5.3 4.8e-11 42.9 5.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGG07707.1 - 2.7e-08 34.0 0.1 1.1e-07 32.0 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGG07707.1 - 0.00022 21.1 0.0 0.075 12.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGG07707.1 - 0.0038 16.7 0.1 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_16 PF13191.6 EGG07707.1 - 0.18 12.2 0.1 0.81 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain CK_II_beta PF01214.18 EGG07711.1 - 1.5e-73 246.5 0.0 1.8e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF4449 PF14613.6 EGG07712.1 - 3e-26 92.5 1.8 3e-26 92.5 1.8 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF4449) Prp18 PF02840.15 EGG07712.1 - 0.095 12.8 5.2 1.6 8.8 0.5 3.8 3 1 1 4 4 4 0 Prp18 domain CdiI_2 PF18593.1 EGG07712.1 - 0.13 13.0 0.3 20 5.9 0.0 3.3 3 0 0 3 3 3 0 CdiI immunity protein Coa1 PF08695.10 EGG07712.1 - 0.19 11.5 0.4 4.5 7.0 0.1 2.4 2 0 0 2 2 2 0 Cytochrome oxidase complex assembly protein 1 Ferritin_2 PF13668.6 EGG07713.1 - 2.5e-44 150.8 1.0 3.4e-44 150.4 1.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF4456 PF14644.6 EGG07714.1 - 0.068 12.8 0.3 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) REPA_OB_2 PF16900.5 EGG07715.1 - 0.065 13.2 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Replication protein A OB domain RMI1_N PF08585.12 EGG07716.1 - 6.5e-50 169.9 3.3 3.2e-49 167.6 0.1 2.1 2 0 0 2 2 2 1 RecQ mediated genome instability protein SPX PF03105.19 EGG07716.1 - 0.045 13.7 6.3 0.071 13.0 6.3 1.3 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 EGG07716.1 - 1.9 7.6 17.1 0.44 9.7 13.5 1.6 2 0 0 2 2 2 0 RAM signalling pathway protein RRM_1 PF00076.22 EGG07717.1 - 2.2e-17 62.6 0.0 3e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.27 EGG07718.1 - 3.2e-36 124.9 0.0 6e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGG07718.1 - 6.4e-20 71.9 11.2 8.3e-20 71.6 11.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGG07718.1 - 5.1e-07 29.3 0.0 9.8e-06 25.2 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGG07718.1 - 8.2e-05 23.1 0.1 0.00022 21.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG07718.1 - 0.00036 20.8 0.0 0.0032 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGG07718.1 - 0.0041 16.8 1.5 0.0047 16.6 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGG07718.1 - 0.0041 16.4 0.0 0.012 14.9 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 EGG07718.1 - 0.0085 15.9 0.2 0.02 14.7 0.1 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGG07718.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 EGG07718.1 - 0.032 14.3 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EGG07718.1 - 0.066 13.2 0.1 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EGG07718.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain NACHT PF05729.12 EGG07718.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.20 EGG07718.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit RICTOR_N PF14664.6 EGG07719.1 - 4.7e-51 173.9 5.7 2.7e-50 171.4 1.8 3.2 3 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EGG07719.1 - 1.4e-35 121.2 4.2 3.1e-33 113.6 0.5 4.2 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EGG07719.1 - 1.5e-33 115.4 0.2 2.6e-32 111.5 0.0 2.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EGG07719.1 - 1.1e-27 96.1 2.9 5.2e-26 90.7 0.2 4.4 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_EZ PF13513.6 EGG07719.1 - 0.00022 21.7 0.0 5.7 7.5 0.0 4.1 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 EGG07719.1 - 0.0044 17.2 1.7 14 6.3 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 EGG07719.1 - 0.038 14.4 0.0 4.9 7.6 0.0 3.4 2 0 0 2 2 2 0 HEAT repeats Ribosomal_L11_N PF03946.14 EGG07720.1 - 2.1e-24 85.1 0.1 3.5e-24 84.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGG07720.1 - 2.6e-18 66.3 0.2 4.6e-18 65.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Colicin PF01024.19 EGG07720.1 - 0.12 12.2 0.5 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 Colicin pore forming domain DUF1748 PF08520.10 EGG07722.1 - 8.7e-25 86.4 0.1 1e-24 86.2 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Ribosomal_L22 PF00237.19 EGG07723.1 - 8.6e-35 119.1 0.7 2.3e-34 117.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Sugar-bind PF04198.13 EGG07723.1 - 0.047 12.8 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Astro_capsid_p PF12226.8 EGG07724.1 - 1.7 7.7 7.8 2.3 7.3 7.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 EGG07724.1 - 2.6 6.2 8.8 3.7 5.7 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGG07724.1 - 4.1 5.5 12.8 6.2 4.9 12.8 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EGG07724.1 - 9.6 5.4 12.4 14 4.9 12.4 1.1 1 0 0 1 1 1 0 NOA36 protein Methyltr_RsmB-F PF01189.17 EGG07725.1 - 7.2e-40 136.8 0.0 8.3e-38 130.0 0.0 2.4 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ribosomal_S27e PF01667.17 EGG07727.1 - 0.073 12.8 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 MPP6 PF10175.9 EGG07729.1 - 1.6e-10 41.6 0.4 1.6e-10 41.6 0.4 2.5 1 1 0 2 2 2 1 M-phase phosphoprotein 6 Utp14 PF04615.13 EGG07729.1 - 0.011 14.3 20.1 0.013 14.1 20.1 1.0 1 0 0 1 1 1 0 Utp14 protein F1F0-ATPsyn_F PF10791.9 EGG07730.1 - 1.1e-37 128.4 0.1 1.2e-37 128.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 EGG07730.1 - 0.0008 19.7 0.0 0.0009 19.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f zf-C2H2 PF00096.26 EGG07731.1 - 5.4e-05 23.4 2.8 5.4e-05 23.4 2.8 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG07731.1 - 0.014 15.8 1.7 0.014 15.8 1.7 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG07731.1 - 0.038 14.8 2.6 0.038 14.8 2.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EGG07731.1 - 0.1 12.7 6.5 1.2 9.3 1.8 2.4 1 1 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 EGG07731.1 - 0.1 12.6 1.0 0.3 11.2 1.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger CRAL_TRIO PF00650.20 EGG07732.1 - 1.7e-29 102.6 0.1 2.4e-29 102.1 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGG07732.1 - 0.018 15.2 1.7 0.034 14.3 0.2 2.4 3 0 0 3 3 3 0 CRAL/TRIO, N-terminal domain aGPT-Pplase1 PF18723.1 EGG07734.1 - 0.046 13.2 0.1 0.094 12.1 0.1 1.5 1 0 0 1 1 1 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 ComFB PF10719.9 EGG07734.1 - 0.16 12.1 0.1 4.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Late competence development protein ComFB Xpo1 PF08389.12 EGG07735.1 - 0.085 12.9 0.0 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Exportin 1-like protein Chitin_synth_2 PF03142.15 EGG07736.1 - 1.6e-273 908.1 0.0 2e-273 907.8 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EGG07736.1 - 6.5e-11 42.5 1.2 6.5e-11 42.5 1.2 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGG07736.1 - 7.9e-11 42.3 0.1 1.3e-09 38.3 0.0 2.7 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGG07736.1 - 0.0012 18.3 0.0 0.59 9.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Reticulon PF02453.17 EGG07736.1 - 5.8 6.9 8.3 0.33 10.9 0.7 2.4 2 0 0 2 2 2 0 Reticulon TYA PF01021.19 EGG07737.1 - 0.0015 18.8 3.3 0.0031 17.8 3.3 1.4 1 0 0 1 1 1 1 TYA transposon protein LrgB PF04172.16 EGG07738.1 - 5.8e-35 120.8 8.1 5.8e-35 120.8 8.1 1.7 3 0 0 3 3 3 1 LrgB-like family PAS_11 PF14598.6 EGG07742.1 - 0.0031 17.6 0.0 0.13 12.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain GATA PF00320.27 EGG07743.1 - 4.5e-13 48.6 2.7 4.5e-13 48.6 2.7 1.8 2 0 0 2 2 2 1 GATA zinc finger DZR PF12773.7 EGG07743.1 - 0.07 13.2 0.6 0.24 11.4 0.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF4449 PF14613.6 EGG07745.1 - 0.00013 22.1 0.0 0.001 19.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Sec23_helical PF04815.15 EGG07745.1 - 0.071 12.9 2.7 6.2 6.7 0.1 3.2 2 1 1 3 3 3 0 Sec23/Sec24 helical domain SWIB PF02201.18 EGG07745.1 - 0.23 11.4 2.3 6.3 6.8 0.3 3.0 1 1 1 2 2 2 0 SWIB/MDM2 domain AbiH PF14253.6 EGG07745.1 - 1.6 8.6 9.5 1.3 8.9 6.1 2.4 2 1 1 3 3 3 0 Bacteriophage abortive infection AbiH Com_YlbF PF06133.11 EGG07745.1 - 2.7 8.6 9.2 1.2 9.8 2.6 3.4 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA Fib_alpha PF08702.10 EGG07745.1 - 6.9 6.8 10.5 4.6 7.4 0.2 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Oleosin PF01277.17 EGG07746.1 - 0.00096 18.9 1.6 0.002 17.9 1.6 1.5 1 0 0 1 1 1 1 Oleosin F-box-like PF12937.7 EGG07747.1 - 0.012 15.5 3.6 0.17 11.8 3.6 2.6 1 1 0 1 1 1 0 F-box-like O-FucT PF10250.9 EGG07749.1 - 2.3e-09 37.4 0.0 8e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase DUF4988 PF16378.5 EGG07749.1 - 0.049 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function zf-C2H2 PF00096.26 EGG07750.1 - 2.4e-05 24.5 15.6 7e-05 23.1 2.5 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG07750.1 - 0.00012 22.3 6.0 0.00012 22.3 6.0 4.7 4 0 0 4 4 4 2 Zinc-finger double domain Auxin_resp PF06507.13 EGG07750.1 - 0.096 13.0 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Auxin response factor Orn_Arg_deC_N PF02784.16 EGG07751.1 - 2.2e-74 250.0 0.0 3.1e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGG07751.1 - 1.9e-11 44.1 0.0 1.3e-10 41.4 0.0 2.2 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Methyltransf_28 PF02636.17 EGG07752.1 - 1.4e-65 221.5 0.0 1.7e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 EGG07752.1 - 0.016 15.9 0.0 0.03 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Git3 PF11710.8 EGG07753.1 - 7.7e-12 45.4 6.0 1.2e-11 44.7 6.0 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EGG07753.1 - 0.0014 18.6 0.3 0.0048 17.0 0.3 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term TPP_enzyme_M PF00205.22 EGG07754.1 - 5.4e-16 58.6 0.1 5.9e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF4407 PF14362.6 EGG07757.1 - 8 5.7 5.9 12 5.1 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IHABP4_N PF16174.5 EGG07757.1 - 8.4 7.0 25.2 0.14 12.8 16.7 2.3 3 0 0 3 3 3 0 Intracellular hyaluronan-binding protein 4 N-terminal EnY2 PF10163.9 EGG07758.1 - 9.3e-18 64.4 0.2 1.5e-17 63.7 0.1 1.4 1 1 0 1 1 1 1 Transcription factor e(y)2 PheRS_DBD2 PF18554.1 EGG07758.1 - 0.081 12.9 1.2 4.2 7.4 0.1 2.9 2 1 0 3 3 3 0 PheRS DNA binding domain 2 MinE PF03776.14 EGG07758.1 - 0.12 12.4 0.5 0.31 11.1 0.1 1.9 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE ERCC3_RAD25_C PF16203.5 EGG07759.1 - 1.2e-123 411.2 0.2 3.7e-123 409.6 0.2 1.9 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EGG07759.1 - 4e-35 120.7 0.8 8.6e-35 119.7 0.8 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG07759.1 - 5.6e-15 55.8 1.1 7.2e-15 55.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGG07759.1 - 8e-14 51.9 0.1 1e-12 48.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EGG07759.1 - 2.8e-07 29.6 0.0 3.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SBP_bac_6 PF13343.6 EGG07759.1 - 0.039 13.4 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein BLOC1_2 PF10046.9 EGG07765.1 - 0.00063 20.0 11.2 0.022 15.1 3.6 2.1 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cortex-I_coil PF09304.10 EGG07765.1 - 0.0079 16.4 5.2 0.011 15.9 5.2 1.1 1 0 0 1 1 1 1 Cortexillin I, coiled coil CHASE3 PF05227.13 EGG07765.1 - 0.015 15.2 1.4 0.021 14.7 1.4 1.3 1 0 0 1 1 1 0 CHASE3 domain FapA PF03961.13 EGG07765.1 - 0.03 12.9 2.9 0.036 12.7 2.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A LXG PF04740.12 EGG07765.1 - 0.053 13.2 7.5 0.074 12.8 7.5 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily AI-2E_transport PF01594.16 EGG07765.1 - 0.084 12.0 1.7 0.11 11.6 1.7 1.2 1 0 0 1 1 1 0 AI-2E family transporter DUF3958 PF13125.6 EGG07765.1 - 0.096 12.9 2.8 0.16 12.2 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) DUF4200 PF13863.6 EGG07765.1 - 0.1 13.0 4.3 0.13 12.6 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF1664 PF07889.12 EGG07765.1 - 0.1 12.6 5.3 0.15 12.1 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YlqD PF11068.8 EGG07765.1 - 0.1 12.9 6.1 0.15 12.4 6.1 1.1 1 0 0 1 1 1 0 YlqD protein V_ATPase_I PF01496.19 EGG07765.1 - 0.11 10.4 2.1 0.13 10.1 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 EGG07765.1 - 0.12 12.9 9.6 0.32 11.5 7.6 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Hema_stalk PF08720.10 EGG07765.1 - 0.12 12.1 1.2 0.2 11.3 1.1 1.5 1 1 0 1 1 1 0 Influenza C hemagglutinin stalk FadA PF09403.10 EGG07765.1 - 0.26 11.8 9.2 0.1 13.1 3.1 2.1 1 1 1 2 2 2 0 Adhesion protein FadA Phage_Mu_Gam PF07352.12 EGG07765.1 - 0.43 10.5 4.8 0.21 11.5 1.9 1.8 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF3450 PF11932.8 EGG07765.1 - 0.65 9.3 10.6 0.88 8.8 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 EGG07765.1 - 0.98 9.9 7.2 4.6 7.8 7.2 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 CLZ PF16526.5 EGG07765.1 - 1.8 9.0 6.3 3.8 8.0 2.3 2.8 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels UCH PF00443.29 EGG07766.1 - 3.6e-23 82.4 4.0 5.3e-23 81.8 4.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG07766.1 - 4.9e-06 26.4 9.8 1.3e-05 24.9 9.8 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EGG07766.1 - 0.001 18.6 6.7 0.21 11.0 0.1 2.9 2 1 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF1041 PF06292.17 EGG07766.1 - 0.014 15.7 2.5 0.11 13.0 0.5 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) THOC7 PF05615.13 EGG07766.1 - 0.026 14.8 2.9 0.053 13.8 2.9 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 DUF4404 PF14357.6 EGG07766.1 - 0.51 11.0 4.7 0.31 11.7 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TMPIT PF07851.13 EGG07766.1 - 0.79 8.9 4.3 0.24 10.6 1.2 1.6 2 0 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 EGG07766.1 - 0.82 9.7 3.9 5.2 7.1 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 EGG07766.1 - 0.9 9.1 4.4 1.5 8.4 0.7 2.2 2 0 0 2 2 2 0 fzo-like conserved region RhoGEF PF00621.20 EGG07767.1 - 4.8e-17 62.8 3.9 4.8e-17 62.8 3.9 4.1 3 2 1 4 4 4 1 RhoGEF domain CNH PF00780.22 EGG07767.1 - 1.3e-15 57.8 3.7 9.2e-07 28.7 2.1 2.6 2 0 0 2 2 2 2 CNH domain PH_5 PF15405.6 EGG07767.1 - 6e-10 39.3 0.1 6e-10 39.3 0.1 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain DUF2791 PF10923.8 EGG07767.1 - 0.028 13.3 0.3 0.049 12.5 0.3 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) SR-25 PF10500.9 EGG07767.1 - 0.27 10.8 12.0 0.66 9.5 12.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MMS1_N PF10433.9 EGG07768.1 - 4.5e-64 216.9 0.0 9.1e-64 215.9 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGG07768.1 - 4.7e-43 147.7 0.1 2.7e-41 141.9 0.0 2.7 3 0 0 3 3 3 2 CPSF A subunit region OPT PF03169.15 EGG07769.1 - 7.3e-64 216.5 23.5 2.2e-51 175.2 13.7 2.3 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Peptidase_S10 PF00450.22 EGG07771.1 - 1.6e-69 235.3 0.1 5.1e-69 233.7 0.1 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase PH_17 PF18012.1 EGG07771.1 - 0.0051 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 PH domain Ras PF00071.22 EGG07772.1 - 8.8e-43 145.7 0.0 1e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG07772.1 - 6.2e-16 58.7 0.0 8.6e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG07772.1 - 0.00026 20.5 0.0 0.0003 20.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG07772.1 - 0.00027 20.5 0.0 0.00068 19.2 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SPOB_a PF14689.6 EGG07773.1 - 0.064 13.0 0.0 0.24 11.1 0.0 2.0 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain S36_mt PF10937.8 EGG07773.1 - 4.6 8.9 9.1 26 6.4 1.3 3.6 1 1 2 3 3 3 0 Ribosomal protein S36, mitochondrial zf-RING_11 PF17123.5 EGG07780.1 - 1.9e-06 27.5 1.5 4.8e-06 26.2 1.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGG07780.1 - 5.2e-06 26.7 0.5 2e-05 24.8 0.5 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG07780.1 - 0.015 15.3 0.6 0.049 13.7 0.6 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG07780.1 - 0.027 14.3 1.2 0.079 12.8 0.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANC_SAP PF18081.1 EGG07780.1 - 0.21 11.8 0.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain DUF3361 PF11841.8 EGG07780.1 - 0.25 11.3 4.8 7 6.6 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) zf-RING_11 PF17123.5 EGG07781.1 - 1.4e-05 24.7 0.7 3.4e-05 23.5 0.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGG07781.1 - 0.00023 21.4 3.1 0.00077 19.8 3.1 1.9 1 0 0 1 1 1 1 Ring finger domain SF3A3 PF16837.5 EGG07781.1 - 2.7 8.6 6.1 34 5.0 2.8 4.0 2 1 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 COPIIcoated_ERV PF07970.12 EGG07782.1 - 4.6e-86 288.2 1.8 6.3e-86 287.8 1.8 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGG07782.1 - 1.7e-24 86.0 0.1 3.6e-24 84.9 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) FPN1 PF06963.12 EGG07784.1 - 7e-104 347.8 12.7 8.1e-104 347.6 12.7 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) U1snRNP70_N PF12220.8 EGG07788.1 - 3.6e-22 78.8 0.4 7e-22 77.9 0.4 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EGG07788.1 - 5e-17 61.5 0.1 7.4e-17 60.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG07788.1 - 0.04 14.0 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif RRM_8 PF11835.8 EGG07788.1 - 0.21 11.8 0.0 0.3 11.3 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain ESM4 PF15952.5 EGG07789.1 - 0.064 13.7 0.9 0.11 13.0 0.9 1.3 1 0 0 1 1 1 0 Enhancer of split M4 family SprA-related PF12118.8 EGG07789.1 - 7.5 5.6 9.7 13 4.8 9.7 1.3 1 0 0 1 1 1 0 SprA-related family ESM4 PF15952.5 EGG07794.1 - 0.064 13.7 0.9 0.11 13.0 0.9 1.3 1 0 0 1 1 1 0 Enhancer of split M4 family SprA-related PF12118.8 EGG07794.1 - 7.5 5.6 9.7 13 4.8 9.7 1.3 1 0 0 1 1 1 0 SprA-related family OPT PF03169.15 EGG07795.1 - 3.1e-138 462.1 21.9 3.6e-138 461.9 21.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein zf-C2H2_jaz PF12171.8 EGG07796.1 - 0.00096 19.4 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG07796.1 - 0.17 12.3 0.4 0.45 11.0 0.4 1.8 1 1 0 1 1 1 0 Zinc-finger of C2H2 type IER PF05760.12 EGG07796.1 - 3.2 8.0 11.1 0.099 12.9 2.4 2.1 1 1 1 2 2 2 0 Immediate early response protein (IER) DUF702 PF05142.12 EGG07797.1 - 0.02 15.3 3.4 0.039 14.4 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) CARMIL_C PF16000.5 EGG07797.1 - 1.8 8.1 12.0 0.16 11.6 3.3 2.2 2 0 0 2 2 2 0 CARMIL C-terminus COG6 PF06419.11 EGG07800.1 - 5.2e-145 484.2 0.8 5.8e-145 484.0 0.8 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 EF_assoc_2 PF08356.12 EGG07801.1 - 1.4e-30 105.2 0.0 4.6e-30 103.4 0.0 1.9 2 0 0 2 2 1 1 EF hand associated EF_assoc_1 PF08355.12 EGG07801.1 - 7.4e-28 96.0 2.4 2.1e-27 94.5 0.6 2.5 3 0 0 3 3 3 1 EF hand associated Ras PF00071.22 EGG07801.1 - 3e-26 91.9 0.0 1.1e-19 70.7 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGG07801.1 - 1.5e-15 57.5 0.0 1.2e-09 38.4 0.0 3.1 3 1 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 EGG07801.1 - 4.8e-08 33.3 1.0 0.0019 18.6 0.1 3.2 2 1 0 2 2 2 2 EF-hand domain pair Arf PF00025.21 EGG07801.1 - 2e-07 30.7 0.1 0.024 14.1 0.0 3.2 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_18 PF13238.6 EGG07801.1 - 3.5e-07 30.8 0.0 0.012 16.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGG07801.1 - 4.2e-07 30.0 0.1 0.067 13.1 0.0 3.8 4 0 0 4 4 4 2 RsgA GTPase MMR_HSR1 PF01926.23 EGG07801.1 - 6.4e-07 29.4 0.0 0.033 14.3 0.0 2.9 2 2 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_6 PF13405.6 EGG07801.1 - 1.5e-06 27.6 2.4 0.036 14.0 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain AAA_22 PF13401.6 EGG07801.1 - 1.7e-06 28.3 0.3 0.011 16.0 0.0 3.4 3 2 0 3 3 2 2 AAA domain EF-hand_1 PF00036.32 EGG07801.1 - 1.3e-05 24.4 6.2 0.026 14.1 0.4 3.0 3 0 0 3 3 2 2 EF hand ABC_tran PF00005.27 EGG07801.1 - 0.00036 21.1 0.0 0.18 12.3 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 EGG07801.1 - 0.00037 20.2 0.1 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 EGG07801.1 - 0.00044 20.3 4.8 0.63 10.1 0.1 3.5 4 0 0 4 4 3 2 Dynamin family RNA_helicase PF00910.22 EGG07801.1 - 0.00051 20.4 0.1 1.1 9.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 EGG07801.1 - 0.00066 19.8 0.2 1.8 8.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain G-alpha PF00503.20 EGG07801.1 - 0.00091 18.5 0.1 0.11 11.6 0.1 2.5 3 0 0 3 3 3 1 G-protein alpha subunit SPARC_Ca_bdg PF10591.9 EGG07801.1 - 0.00095 19.5 2.3 0.33 11.3 0.0 3.4 2 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 EGG07801.1 - 0.0012 18.2 4.3 1 8.9 1.1 3.0 2 0 0 2 2 2 2 EF hand ATP_bind_1 PF03029.17 EGG07801.1 - 0.0015 18.4 1.2 7.1 6.3 0.1 4.0 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein EF-hand_10 PF14788.6 EGG07801.1 - 0.0039 17.0 2.4 0.075 12.9 0.1 2.4 2 0 0 2 2 2 1 EF hand AAA PF00004.29 EGG07801.1 - 0.0052 17.2 0.0 2.5 8.5 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGG07801.1 - 0.0059 16.1 0.0 0.79 9.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 EGG07801.1 - 0.0067 15.6 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EGG07801.1 - 0.0071 16.7 0.1 4.4 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 EGG07801.1 - 0.014 15.1 0.0 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EGG07801.1 - 0.022 14.0 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_28 PF13521.6 EGG07801.1 - 0.024 14.9 0.0 9.5 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 EGG07801.1 - 0.025 14.4 2.7 0.77 9.7 0.1 2.9 3 0 0 3 3 2 0 EF-hand domain pair TsaE PF02367.17 EGG07801.1 - 0.037 14.0 0.0 4 7.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE VirE PF05272.11 EGG07801.1 - 0.049 13.4 0.0 5.4 6.7 0.0 2.6 2 0 0 2 2 2 0 Virulence-associated protein E NB-ARC PF00931.22 EGG07801.1 - 0.083 12.1 0.0 7.3 5.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 EGG07801.1 - 0.087 12.5 0.0 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EGG07801.1 - 0.095 12.6 0.1 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MCM PF00493.23 EGG07801.1 - 0.1 11.7 0.0 0.36 9.9 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain Viral_helicase1 PF01443.18 EGG07801.1 - 0.11 12.2 0.0 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 EGG07801.1 - 0.11 12.9 0.1 1.4 9.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGG07801.1 - 0.13 11.5 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin NOG1 PF06858.14 EGG07801.1 - 0.19 11.5 0.8 19 5.1 0.0 2.8 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_32 PF13654.6 EGG07801.1 - 0.22 10.3 0.1 0.82 8.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGG07801.1 - 0.32 11.5 0.9 3.3 8.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain eIF3_subunit PF08597.10 EGG07802.1 - 0.045 13.7 6.0 0.053 13.4 6.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit AP1AR PF15745.5 EGG07802.1 - 0.098 12.3 10.2 0.11 12.1 10.2 1.0 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein CC2D2AN-C2 PF15625.6 EGG07802.1 - 0.14 11.9 0.2 0.16 11.7 0.2 1.2 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain DUF4337 PF14235.6 EGG07802.1 - 0.14 12.2 3.5 0.16 12.1 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Folate_carrier PF01770.18 EGG07802.1 - 0.15 10.8 0.2 0.17 10.6 0.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF1764 PF08576.10 EGG07802.1 - 0.43 11.5 6.8 0.51 11.3 6.8 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Borrelia_P83 PF05262.11 EGG07802.1 - 4.4 5.7 12.0 4.8 5.5 12.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein RRM_1 PF00076.22 EGG07803.1 - 2.9e-10 39.8 0.0 4.7e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG07803.1 - 0.00077 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EGG07803.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Cyclin_N PF00134.23 EGG07806.1 - 1.6e-45 153.9 1.4 4.5e-44 149.3 0.8 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGG07806.1 - 1.1e-27 96.5 0.1 2.2e-27 95.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain PI31_Prot_C PF08577.11 EGG07807.1 - 4.9e-14 53.3 5.9 4.9e-14 53.3 5.9 2.9 3 0 0 3 3 3 1 PI31 proteasome regulator PI31_Prot_N PF11566.8 EGG07807.1 - 1e-09 38.4 0.2 8e-08 32.3 0.0 2.4 1 1 1 2 2 2 2 PI31 proteasome regulator N-terminal DEC-1_N PF04625.13 EGG07807.1 - 9.2 5.2 8.2 13 4.7 8.2 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ABA_WDS PF02496.16 EGG07808.1 - 0.038 14.5 0.2 0.065 13.7 0.2 1.3 1 0 0 1 1 1 0 ABA/WDS induced protein Serinc PF03348.15 EGG07809.1 - 4.1e-139 464.2 11.6 4.7e-139 464.0 11.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) ECSCR PF15820.5 EGG07809.1 - 2.9 7.8 4.3 5.7 6.8 0.1 2.8 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator SLATT_6 PF18169.1 EGG07810.1 - 0.011 15.3 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Claudin_2 PF13903.6 EGG07810.1 - 0.081 12.7 0.6 0.12 12.1 0.5 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction zf-C2H2_2 PF12756.7 EGG07812.1 - 0.049 14.0 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ApoLp-III PF07464.11 EGG07813.1 - 0.0055 16.8 0.2 0.06 13.4 0.2 2.3 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 EGG07813.1 - 0.01 15.9 2.0 0.021 14.9 1.3 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 EGG07813.1 - 0.04 13.8 0.1 0.085 12.7 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Focal_AT PF03623.13 EGG07813.1 - 0.063 13.3 0.7 0.86 9.6 0.2 2.2 2 0 0 2 2 2 0 Focal adhesion targeting region MCPsignal PF00015.21 EGG07813.1 - 0.093 12.5 0.7 0.37 10.6 1.0 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CSN5_C PF18323.1 EGG07813.1 - 0.11 13.5 0.0 0.44 11.5 0.0 2.1 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Gemini_AL1 PF00799.20 EGG07813.1 - 0.14 12.5 0.1 1.9 8.9 0.0 2.2 2 0 0 2 2 2 0 Geminivirus Rep catalytic domain DUF824 PF05688.11 EGG07813.1 - 0.83 9.5 5.0 5.7 6.8 0.2 2.9 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) RPAP1_N PF08621.10 EGG07813.1 - 1.8 8.4 4.8 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 RPAP1-like, N-terminal GATA PF00320.27 EGG07814.1 - 9.6e-30 101.9 16.0 2e-15 56.1 2.2 2.4 2 0 0 2 2 2 2 GATA zinc finger zf-RRPl_C4 PF17026.5 EGG07814.1 - 0.0011 19.0 1.7 0.34 11.0 0.5 2.5 1 1 1 2 2 2 2 Putative ribonucleoprotein zinc-finger pf C4 type ArfGap PF01412.18 EGG07814.1 - 0.0071 16.4 7.3 0.25 11.4 1.9 2.2 1 1 1 2 2 2 2 Putative GTPase activating protein for Arf FAM76 PF16046.5 EGG07814.1 - 0.026 13.9 3.7 0.036 13.4 3.7 1.2 1 0 0 1 1 1 0 FAM76 protein Auto_anti-p27 PF06677.12 EGG07814.1 - 0.04 14.1 6.0 0.77 10.0 0.7 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 EGG07814.1 - 0.067 13.1 4.1 2 8.3 0.2 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-B_box PF00643.24 EGG07814.1 - 0.2 11.8 0.1 0.2 11.8 0.1 3.8 3 1 0 3 3 3 0 B-box zinc finger OTT_1508_deam PF14441.6 EGG07814.1 - 0.43 10.6 4.4 1.5 8.9 0.1 2.5 2 1 0 2 2 2 0 OTT_1508-like deaminase DZR PF12773.7 EGG07814.1 - 0.67 10.0 12.9 2.6 8.1 10.0 3.0 1 1 1 2 2 2 0 Double zinc ribbon ZF-HD_dimer PF04770.12 EGG07814.1 - 0.71 10.2 0.1 0.71 10.2 0.1 3.9 2 2 1 4 4 4 0 ZF-HD protein dimerisation region Zn-ribbon_8 PF09723.10 EGG07814.1 - 2.3 8.4 9.7 13 6.0 0.9 3.3 2 2 2 4 4 4 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 EGG07814.1 - 2.8 7.5 7.7 14 5.3 0.2 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.6 EGG07814.1 - 3.7 8.1 8.2 2.1 8.9 0.3 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_2 PF13240.6 EGG07814.1 - 4.2 7.2 11.3 44 4.0 0.2 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Elf1 PF05129.13 EGG07814.1 - 9.5 6.3 7.7 4.4 7.4 1.7 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Peptidase_S9 PF00326.21 EGG07815.1 - 1.2e-30 106.6 0.0 2.4e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGG07815.1 - 6.7e-05 22.3 0.1 0.076 12.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EGG07815.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EGG07815.1 - 0.0044 16.7 2.0 0.14 11.8 0.3 2.6 2 1 1 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.20 EGG07815.1 - 0.005 16.5 0.0 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 EGG07815.1 - 0.051 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EGG07815.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S28 PF05577.12 EGG07815.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 RRM_1 PF00076.22 EGG07816.1 - 1.2e-12 47.5 0.0 2.5e-05 24.0 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG07816.1 - 2.2e-06 27.7 0.0 4.5e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif SCP2 PF02036.17 EGG07818.1 - 1.2e-14 54.6 0.0 1.7e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EGG07818.1 - 0.00021 21.6 0.0 0.00026 21.2 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 EGG07818.1 - 0.066 13.6 0.0 0.084 13.3 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain RXT2_N PF08595.11 EGG07820.1 - 0.0005 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 RXT2-like, N-terminal Myb_DNA-bind_3 PF12776.7 EGG07822.1 - 3.5e-15 56.8 0.7 6.9e-15 55.8 0.7 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGG07822.1 - 9.4e-05 22.7 0.3 0.0014 19.0 0.0 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MRP-L47 PF06984.13 EGG07823.1 - 1e-17 64.0 0.1 3.2e-17 62.4 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) CPSF100_C PF13299.6 EGG07824.1 - 0.33 11.1 3.1 1 9.5 3.1 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CxC5 PF18718.1 EGG07826.1 - 9.5e-32 109.5 3.8 1.5e-31 108.9 3.8 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 EGG07826.1 - 0.069 13.0 0.6 0.21 11.4 0.2 2.0 1 1 1 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases Ribosomal_L1 PF00687.21 EGG07827.1 - 2.3e-53 181.0 0.4 3.2e-53 180.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF5327 PF17261.2 EGG07828.1 - 1.4 9.7 13.5 3.6 8.4 10.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5327) F-box-like PF12937.7 EGG07829.1 - 0.054 13.4 2.1 0.18 11.7 2.1 2.0 1 1 0 1 1 1 0 F-box-like Cytomega_US3 PF05963.11 EGG07830.1 - 0.055 13.1 0.0 0.12 12.0 0.1 1.6 2 0 0 2 2 2 0 Cytomegalovirus US3 protein BUD22 PF09073.10 EGG07831.1 - 0.27 10.5 21.4 0.35 10.1 21.4 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EGG07831.1 - 0.42 8.8 31.6 0.48 8.6 31.6 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 EGG07831.1 - 0.96 8.8 15.6 1.2 8.5 15.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIA PF03153.13 EGG07831.1 - 9.4 6.1 29.6 13 5.7 29.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mucin PF01456.17 EGG07835.1 - 0.71 9.9 13.4 0.14 12.1 9.0 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein PPR_2 PF13041.6 EGG07837.1 - 3.7e-10 39.8 0.2 0.0031 17.7 0.0 4.5 3 1 2 5 5 5 3 PPR repeat family PPR_1 PF12854.7 EGG07837.1 - 2.3e-07 30.4 0.3 0.73 9.6 0.1 4.3 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 EGG07837.1 - 1.7e-06 28.0 0.1 0.04 14.0 0.0 3.5 1 1 4 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.20 EGG07837.1 - 0.019 15.2 5.0 5.1 7.6 0.0 5.1 5 1 0 5 5 5 0 PPR repeat CDC37_N PF03234.14 EGG07838.1 - 3.3e-35 121.8 7.2 3.5e-35 121.7 7.2 1.0 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding PRP1_N PF06424.12 EGG07838.1 - 0.69 10.3 6.1 0.75 10.2 6.1 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Tweety PF04906.13 EGG07842.1 - 0.0014 17.4 0.3 0.0022 16.7 0.3 1.3 1 0 0 1 1 1 1 Tweety NPV_P10 PF05531.12 EGG07842.1 - 0.0051 17.3 1.1 0.14 12.7 1.0 2.4 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Retrotran_gag_2 PF14223.6 EGG07842.1 - 0.012 15.3 1.9 0.019 14.6 1.9 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Baculo_PEP_C PF04513.12 EGG07842.1 - 0.021 14.9 1.5 0.036 14.1 1.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EGG07842.1 - 0.029 13.3 0.2 0.035 13.0 0.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CREPT PF16566.5 EGG07842.1 - 0.037 14.2 1.1 6.6 6.9 0.2 2.1 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Filament PF00038.21 EGG07842.1 - 0.052 13.1 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein DUF4763 PF15960.5 EGG07842.1 - 0.11 11.8 2.4 0.2 10.9 2.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) TAF4 PF05236.14 EGG07846.1 - 0.0021 17.9 8.5 0.0026 17.6 8.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family RR_TM4-6 PF06459.12 EGG07846.1 - 0.0059 16.5 1.4 0.0063 16.4 1.4 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EGG07846.1 - 3.8 6.2 5.9 4.6 5.9 5.9 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 EGG07847.1 - 0.32 11.0 5.2 0.55 10.2 5.2 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Acyl-CoA_dh_1 PF00441.24 EGG07847.1 - 0.84 9.8 9.5 0.75 10.0 1.8 2.2 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain PhnG PF06754.12 EGG07847.1 - 1.6 8.7 10.8 0.095 12.6 2.6 2.1 1 1 1 2 2 2 0 Phosphonate metabolism protein PhnG NAM-associated PF14303.6 EGG07848.1 - 2.8e-05 24.9 4.6 4.3e-05 24.3 4.6 1.4 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain KCT2 PF17818.1 EGG07849.1 - 0.075 13.2 0.1 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 Keratinocyte-associated gene product RP-C PF03428.13 EGG07849.1 - 0.089 12.4 2.0 0.12 12.0 2.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Aminotran_1_2 PF00155.21 EGG07850.1 - 5.8e-84 282.3 0.0 6.6e-84 282.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF5314 PF17241.2 EGG07850.1 - 0.11 12.1 0.1 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5314) GCM PF03615.15 EGG07853.1 - 0.22 11.4 5.5 2.3 8.1 5.5 2.3 1 1 0 1 1 1 0 GCM motif protein Baculo_PEP_C PF04513.12 EGG07855.1 - 2.6e-05 24.3 0.3 5e-05 23.4 0.3 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 EGG07855.1 - 0.0025 18.2 3.7 0.29 11.5 0.3 3.6 3 0 0 3 3 3 1 Lipoprotein leucine-zipper AAA_13 PF13166.6 EGG07855.1 - 0.0025 16.5 1.5 0.0034 16.1 1.5 1.2 1 0 0 1 1 1 1 AAA domain CEP63 PF17045.5 EGG07855.1 - 0.0091 15.9 1.5 0.016 15.1 1.5 1.4 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa ApoLp-III PF07464.11 EGG07855.1 - 0.011 15.8 2.2 0.027 14.5 2.2 1.6 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) RPW8 PF05659.11 EGG07855.1 - 0.015 15.0 4.1 0.91 9.2 0.8 2.8 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 LXG PF04740.12 EGG07855.1 - 0.024 14.4 2.7 1 9.1 0.1 2.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily Lectin_N PF03954.14 EGG07855.1 - 0.032 14.0 1.6 0.18 11.5 1.6 2.2 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain YscO PF07321.12 EGG07855.1 - 0.035 14.1 1.9 0.041 13.8 0.5 1.7 1 1 1 2 2 2 0 Type III secretion protein YscO IFT57 PF10498.9 EGG07855.1 - 0.054 12.4 6.3 0.19 10.7 6.3 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 CLZ PF16526.5 EGG07855.1 - 0.057 13.8 1.8 0.25 11.7 0.3 2.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 EGG07855.1 - 0.074 12.4 1.1 3.1 7.1 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Phasin PF05597.11 EGG07855.1 - 0.11 12.5 1.8 0.28 11.2 1.8 1.8 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TMPIT PF07851.13 EGG07855.1 - 0.11 11.7 3.0 0.2 10.8 3.0 1.5 1 0 0 1 1 1 0 TMPIT-like protein DUF4618 PF15397.6 EGG07855.1 - 0.12 11.8 3.4 0.21 11.0 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) TPR_MLP1_2 PF07926.12 EGG07855.1 - 0.12 12.4 3.0 0.31 11.1 2.5 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 EGG07855.1 - 0.14 12.2 4.0 0.21 11.6 2.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4094 PF13334.6 EGG07855.1 - 0.17 12.3 2.7 6.9 7.2 1.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) FAM184 PF15665.5 EGG07855.1 - 0.22 11.3 5.0 0.4 10.4 5.0 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Fib_alpha PF08702.10 EGG07855.1 - 0.23 11.7 4.7 6.6 6.9 0.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.6 EGG07855.1 - 0.23 11.9 1.6 3.2 8.2 1.5 2.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Laminin_II PF06009.12 EGG07855.1 - 0.24 11.4 4.4 1.2 9.1 1.0 2.5 1 1 1 2 2 2 0 Laminin Domain II Prominin PF05478.11 EGG07855.1 - 0.29 9.0 2.7 0.43 8.5 2.7 1.1 1 0 0 1 1 1 0 Prominin Vac_Fusion PF02346.16 EGG07855.1 - 0.3 10.7 1.7 6.4 6.5 0.0 3.0 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF724 PF05266.14 EGG07855.1 - 0.31 10.9 5.5 0.54 10.1 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FliD_N PF02465.18 EGG07855.1 - 0.38 11.5 11.1 0.087 13.5 4.6 2.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus BRE1 PF08647.11 EGG07855.1 - 0.39 10.8 6.6 0.36 10.9 1.8 2.6 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Bacillus_HBL PF05791.11 EGG07855.1 - 0.57 10.0 6.7 1.7 8.5 3.1 2.6 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) NPV_P10 PF05531.12 EGG07855.1 - 0.58 10.7 3.6 24 5.5 3.6 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 EGG07855.1 - 1.1 10.0 3.4 7.5 7.3 1.3 2.7 1 1 1 2 2 2 0 Occludin homology domain ABC_tran_CTD PF16326.5 EGG07855.1 - 1.4 9.2 4.4 30 4.9 0.2 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4200 PF13863.6 EGG07855.1 - 1.5 9.2 6.4 4.4 7.7 6.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) OmpH PF03938.14 EGG07855.1 - 1.8 8.9 6.1 0.23 11.8 1.6 1.8 2 1 0 2 2 1 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.22 EGG07855.1 - 2.1 8.6 6.9 2.4 8.4 4.2 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin_2 PF01920.20 EGG07855.1 - 2.2 8.3 7.1 11 6.0 2.0 3.0 1 1 2 3 3 3 0 Prefoldin subunit Prefoldin PF02996.17 EGG07855.1 - 4.3 7.3 7.2 14 5.7 1.4 3.1 2 1 1 3 3 3 0 Prefoldin subunit DUF16 PF01519.16 EGG07855.1 - 6 7.4 9.0 66 4.1 9.0 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 SlyX PF04102.12 EGG07856.1 - 0.13 12.9 2.8 0.22 12.2 0.2 2.8 4 0 0 4 4 4 0 SlyX DUF948 PF06103.11 EGG07856.1 - 0.21 11.9 0.9 0.47 10.7 0.9 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Trimer_CC PF08954.11 EGG07856.1 - 9.3 5.9 7.7 6 6.5 0.3 3.4 3 0 0 3 3 3 0 Trimerisation motif MFS_1 PF07690.16 EGG07860.1 - 9.1e-13 47.8 47.4 1.1e-06 27.9 16.0 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.16 EGG07861.1 - 1e-07 31.2 19.7 1e-07 31.2 19.7 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FOXP-CC PF16159.5 EGG07864.1 - 0.0011 19.5 1.4 0.88 10.2 0.3 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-TRAF PF02176.18 EGG07864.1 - 0.11 13.2 0.6 2.7 8.8 0.0 2.1 1 1 0 2 2 2 0 TRAF-type zinc finger zf-Di19 PF05605.12 EGG07864.1 - 0.16 12.3 0.2 0.25 11.7 0.2 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 EGG07864.1 - 0.27 11.5 2.4 1.4 9.2 2.4 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-H2C2_2 PF13465.6 EGG07864.1 - 0.52 10.8 4.9 0.36 11.3 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger double domain FOXP-CC PF16159.5 EGG07866.1 - 0.00089 19.8 1.7 1.2 9.8 0.3 2.7 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-TRAF PF02176.18 EGG07866.1 - 0.17 12.6 0.6 5.1 7.9 0.0 2.0 1 1 0 2 2 2 0 TRAF-type zinc finger zf-H2C2_2 PF13465.6 EGG07866.1 - 0.27 11.7 4.8 0.34 11.4 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger double domain IBR PF01485.21 EGG07866.1 - 0.31 11.3 2.5 1.9 8.8 2.5 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Snf7 PF03357.21 EGG07867.1 - 3.1e-38 131.1 23.8 4.1e-38 130.7 23.8 1.1 1 0 0 1 1 1 1 Snf7 DUF2218 PF09981.9 EGG07867.1 - 0.099 13.0 0.2 0.27 11.6 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) SLATT_5 PF18160.1 EGG07867.1 - 0.19 11.1 0.6 0.46 9.8 0.6 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 P5CR_dimer PF14748.6 EGG07869.1 - 2.4e-37 127.3 4.5 2e-36 124.4 2.3 2.2 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EGG07869.1 - 7.7e-12 45.7 0.2 7.8e-09 36.0 0.1 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent AMP-binding PF00501.28 EGG07870.1 - 1.7e-16 59.9 0.0 4.8e-16 58.4 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme HMD PF03201.16 EGG07870.1 - 0.0037 17.5 0.0 0.0077 16.4 0.0 1.5 1 0 0 1 1 1 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase GBP_PSP PF02425.15 EGG07870.1 - 0.14 11.8 0.2 0.44 10.2 0.2 1.9 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide NAD_binding_6 PF08030.12 EGG07872.1 - 2.9e-25 89.2 0.0 4.9e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGG07872.1 - 1.3e-19 70.2 0.0 2.4e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EGG07872.1 - 5.1e-09 36.3 6.4 9.6e-09 35.4 6.4 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component 2TM PF13239.6 EGG07872.1 - 0.047 14.0 0.2 0.15 12.4 0.2 1.9 1 0 0 1 1 1 0 2TM domain NAD_binding_1 PF00175.21 EGG07872.1 - 0.061 14.0 0.0 0.72 10.5 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Borrelia_P83 PF05262.11 EGG07874.1 - 2 6.8 23.6 2.7 6.4 23.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3984 PF13136.6 EGG07876.1 - 0.019 14.4 8.0 0.025 14.0 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF4746 PF15928.5 EGG07876.1 - 0.019 14.4 6.7 0.023 14.1 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 EGG07876.1 - 0.3 10.4 10.0 0.36 10.1 10.0 1.2 1 0 0 1 1 1 0 NOA36 protein GEMIN8 PF15348.6 EGG07876.1 - 0.39 11.0 12.6 0.49 10.7 12.6 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DNA_pol_phi PF04931.13 EGG07876.1 - 0.74 7.8 16.1 0.84 7.7 16.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 EGG07876.1 - 5.4 5.0 8.7 6.5 4.7 8.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Filament PF00038.21 EGG07877.1 - 0.002 17.8 1.5 0.002 17.8 1.5 2.1 3 0 0 3 3 3 1 Intermediate filament protein Cep57_MT_bd PF06657.13 EGG07877.1 - 0.0057 17.1 4.1 0.024 15.1 0.1 3.3 3 1 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.12 EGG07877.1 - 0.049 13.7 1.8 0.13 12.3 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 EGG07877.1 - 4 7.8 12.2 0.64 10.4 6.5 2.2 2 0 0 2 2 2 0 Fez1 UPF0242 PF06785.11 EGG07877.1 - 5.6 7.0 14.0 0.32 11.1 3.4 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 EGG07877.1 - 6.3 6.8 16.6 0.14 12.2 5.2 2.8 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EGG07877.1 - 9.9 4.9 12.4 0.05 12.5 2.8 2.0 3 0 0 3 3 3 0 Spc7 kinetochore protein Cep57_MT_bd PF06657.13 EGG07881.1 - 3.9e-19 68.9 1.9 3.9e-19 68.9 1.9 4.1 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 COG2 PF06148.11 EGG07881.1 - 0.097 12.8 2.4 2.6 8.1 2.4 3.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 EGG07881.1 - 0.34 10.9 6.0 0.17 11.9 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EGG07881.1 - 1.4 8.9 7.5 1 9.4 2.2 3.0 2 0 0 2 2 2 0 Laminin Domain II YppG PF14179.6 EGG07882.1 - 0.11 13.2 2.4 0.28 11.9 2.4 1.7 1 0 0 1 1 1 0 YppG-like protein SET PF00856.28 EGG07883.1 - 6.8e-17 62.4 0.2 4.5e-16 59.7 0.2 2.1 1 1 0 1 1 1 1 SET domain N-SET PF11764.8 EGG07883.1 - 0.00019 21.6 0.4 0.00029 21.0 0.4 1.2 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N MSC PF09402.10 EGG07885.1 - 4.1e-15 56.1 0.7 6.1e-15 55.5 0.7 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Cu-oxidase_3 PF07732.15 EGG07886.1 - 2.2e-44 150.3 0.3 3.5e-42 143.2 0.1 2.9 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG07886.1 - 1.9e-34 118.3 1.3 6.8e-29 100.3 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGG07886.1 - 2.3e-24 86.3 0.0 2.9e-23 82.7 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase CxC6 PF18721.1 EGG07887.1 - 1e-20 73.8 1.1 1e-20 73.8 1.1 2.8 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 EGG07887.1 - 1.8e-08 34.4 7.0 8.5e-08 32.3 0.8 2.6 2 0 0 2 2 2 2 CxC5 like cysteine cluster associated with KDZ transposases CHZ PF09649.10 EGG07888.1 - 0.12 11.9 4.3 0.28 10.7 1.6 2.3 2 0 0 2 2 2 0 Histone chaperone domain CHZ PET10 PF17316.2 EGG07889.1 - 0.025 14.1 0.2 0.054 13.0 0.2 1.6 1 1 0 1 1 1 0 Petite colonies protein 10 Collagen PF01391.18 EGG07890.1 - 3.1e-15 55.6 52.7 7e-10 38.5 22.4 4.3 2 1 2 4 4 4 2 Collagen triple helix repeat (20 copies) Drf_FH1 PF06346.12 EGG07890.1 - 0.0003 20.6 12.8 0.0003 20.6 12.8 3.8 2 1 1 3 3 3 1 Formin Homology Region 1 F-box-like PF12937.7 EGG07891.1 - 0.0005 19.9 1.8 0.0012 18.7 1.8 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EGG07891.1 - 0.0033 17.8 0.1 0.0033 17.8 0.1 6.6 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) EST1 PF10374.9 EGG07891.1 - 0.19 12.3 10.4 0.11 13.2 3.1 2.7 2 0 0 2 2 2 0 Telomerase activating protein Est1 Siva PF05458.12 EGG07892.1 - 0.051 13.2 0.1 0.067 12.9 0.1 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) PP2C PF00481.21 EGG07893.1 - 2.1e-27 96.4 0.0 4.8e-24 85.4 0.0 2.5 2 1 1 3 3 3 2 Protein phosphatase 2C SR-25 PF10500.9 EGG07893.1 - 1.5 8.3 16.8 3.1 7.4 16.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LSM PF01423.22 EGG07894.1 - 4.8e-19 67.8 0.2 5.6e-19 67.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain DMRL_synthase PF00885.19 EGG07895.1 - 4.1e-49 166.0 0.0 5e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Ins_allergen_rp PF06757.13 EGG07896.1 - 0.016 15.2 0.3 0.035 14.1 0.3 1.5 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification DUF3189 PF11385.8 EGG07896.1 - 0.11 12.4 0.2 11 5.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3189) DUF918 PF06033.11 EGG07897.1 - 0.033 14.2 0.0 0.052 13.6 0.0 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) GTP_EFTU PF00009.27 EGG07898.1 - 9e-53 178.7 0.0 1.5e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGG07898.1 - 8e-13 48.2 0.0 3.1e-12 46.3 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EGG07898.1 - 8.4e-08 32.2 0.1 2.2e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EGG07898.1 - 1.8e-05 25.0 0.0 4.8e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 EGG07898.1 - 0.004 16.9 0.0 0.026 14.3 0.0 2.3 1 1 1 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 EGG07898.1 - 0.026 14.6 0.0 0.072 13.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase LpxB PF02684.15 EGG07901.1 - 0.075 11.9 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase PhoLip_ATPase_C PF16212.5 EGG07902.1 - 3.5e-80 269.4 23.1 3.5e-80 269.4 23.1 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGG07902.1 - 1.1e-26 92.3 8.1 2.9e-26 90.9 8.1 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGG07902.1 - 3e-15 56.1 0.1 2.2e-14 53.3 0.0 2.5 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGG07902.1 - 4.5e-14 53.2 0.5 2.6e-08 34.4 0.1 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGG07902.1 - 5.2e-08 32.6 0.0 2.6e-07 30.3 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGG07902.1 - 0.00036 20.4 0.1 0.0017 18.1 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DNA_III_psi PF03603.13 EGG07902.1 - 0.058 13.6 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase III psi subunit DUF5102 PF17104.5 EGG07902.1 - 0.24 11.4 2.2 0.53 10.3 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) ABC_tran PF00005.27 EGG07903.1 - 4.2e-42 143.9 0.0 8.1e-20 71.7 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGG07903.1 - 4.6e-21 74.6 3.7 4.6e-21 74.6 3.7 2.4 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 EGG07903.1 - 1.1e-15 58.3 5.5 0.00056 19.8 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG07903.1 - 4.2e-08 32.9 3.2 0.6 9.5 0.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGG07903.1 - 3.8e-07 29.7 0.1 0.0054 16.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGG07903.1 - 7.9e-07 29.8 9.9 0.0095 16.5 0.0 4.2 5 0 0 5 5 4 2 AAA domain AAA_24 PF13479.6 EGG07903.1 - 3.4e-06 26.9 0.3 0.29 10.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EGG07903.1 - 4.1e-06 26.8 4.0 0.0013 18.7 0.0 3.7 4 0 0 4 4 4 1 RsgA GTPase AAA_16 PF13191.6 EGG07903.1 - 6e-06 26.7 0.0 0.059 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EGG07903.1 - 1.1e-05 25.5 0.4 0.042 13.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 EGG07903.1 - 2.1e-05 24.5 0.1 0.018 15.1 0.0 3.3 3 1 0 3 3 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EGG07903.1 - 2.3e-05 24.7 1.9 0.2 11.9 0.0 3.4 3 2 0 3 3 2 2 AAA domain AAA_15 PF13175.6 EGG07903.1 - 2.8e-05 24.0 11.1 0.019 14.7 0.2 4.5 3 2 1 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 EGG07903.1 - 0.00016 22.2 0.0 0.83 10.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EGG07903.1 - 0.00026 21.3 0.0 1 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGG07903.1 - 0.00039 20.8 2.9 4.8 7.6 0.0 3.8 3 0 0 3 3 3 0 RNA helicase DUF87 PF01935.17 EGG07903.1 - 0.00067 19.8 6.2 1.3 9.1 0.1 4.2 3 1 1 4 4 4 1 Helicase HerA, central domain Pox_A32 PF04665.12 EGG07903.1 - 0.0016 18.0 1.5 0.17 11.3 0.0 3.0 3 0 0 3 3 3 1 Poxvirus A32 protein Roc PF08477.13 EGG07903.1 - 0.0016 18.6 0.0 2.1 8.6 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 EGG07903.1 - 0.0031 16.8 1.0 3.2 7.0 0.0 3.1 3 0 0 3 3 3 1 Septin G-alpha PF00503.20 EGG07903.1 - 0.0035 16.6 0.3 0.7 9.0 0.0 2.5 2 1 0 2 2 2 1 G-protein alpha subunit AAA PF00004.29 EGG07903.1 - 0.0038 17.6 0.7 5.2 7.5 0.0 3.9 4 1 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGG07903.1 - 0.0043 16.8 0.0 2.3 7.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EGG07903.1 - 0.0058 16.3 0.1 0.33 10.6 0.0 2.6 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 EGG07903.1 - 0.0062 16.7 0.2 2.5 8.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 EGG07903.1 - 0.0069 15.6 0.0 1.7 7.8 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 EGG07903.1 - 0.0069 16.0 0.0 5.1 6.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain MtrA PF04208.14 EGG07903.1 - 0.0078 15.9 0.2 0.019 14.6 0.2 1.6 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit A NTPase_1 PF03266.15 EGG07903.1 - 0.0083 16.0 0.7 2.4 8.0 0.1 3.2 3 0 0 3 3 3 1 NTPase Dynamin_N PF00350.23 EGG07903.1 - 0.0096 16.0 7.2 0.55 10.3 0.3 3.7 2 1 1 3 3 3 1 Dynamin family FtsK_SpoIIIE PF01580.18 EGG07903.1 - 0.0099 15.3 0.1 3.8 6.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_5 PF07728.14 EGG07903.1 - 0.01 15.8 0.3 5 7.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGG07903.1 - 0.015 14.8 0.2 7 6.1 0.0 3.1 3 0 0 3 3 3 0 P-loop containing dynein motor region cobW PF02492.19 EGG07903.1 - 0.017 14.8 0.9 2.2 7.9 0.0 3.2 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 EGG07903.1 - 0.024 14.7 0.4 1.6 8.8 0.1 3.2 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EGG07903.1 - 0.03 14.0 1.5 2.5 7.7 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EGG07903.1 - 0.033 13.5 0.0 0.66 9.2 0.1 2.6 3 0 0 3 3 2 0 Zeta toxin FeoB_N PF02421.18 EGG07903.1 - 0.035 13.6 0.0 1.1 8.7 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B ATPase PF06745.13 EGG07903.1 - 0.05 12.9 0.3 5.3 6.3 0.0 3.0 3 0 0 3 3 3 0 KaiC ATP_bind_1 PF03029.17 EGG07903.1 - 0.057 13.2 0.6 1.9 8.2 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MobB PF03205.14 EGG07903.1 - 0.063 13.2 0.1 18 5.2 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.21 EGG07903.1 - 0.071 12.6 0.0 16 4.9 0.0 3.0 2 0 0 2 2 2 0 ADP-ribosylation factor family PduV-EutP PF10662.9 EGG07903.1 - 0.078 12.7 5.7 4.3 7.1 0.0 3.7 4 1 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.26 EGG07903.1 - 0.087 12.5 0.0 8.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain FtsK_gamma PF09397.10 EGG07903.1 - 0.11 12.3 0.3 0.4 10.5 0.1 2.0 2 0 0 2 2 1 0 Ftsk gamma domain AAA_13 PF13166.6 EGG07903.1 - 0.13 10.9 8.3 2.8 6.5 0.0 4.1 3 1 1 4 4 4 0 AAA domain DivIC PF04977.15 EGG07903.1 - 0.17 11.6 8.3 2.2 8.1 1.1 2.6 2 0 0 2 2 2 0 Septum formation initiator ABC_membrane PF00664.23 EGG07904.1 - 6.7e-46 157.1 2.2 9.8e-46 156.6 2.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGG07904.1 - 2.2e-31 109.2 0.0 4e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGG07904.1 - 2e-05 24.2 0.7 0.0021 17.5 0.1 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGG07904.1 - 9.4e-05 22.7 0.1 0.00084 19.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG07904.1 - 0.0028 18.1 0.1 0.0087 16.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EGG07904.1 - 0.0031 16.8 0.0 0.0078 15.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 EGG07904.1 - 0.0059 16.3 0.4 0.017 14.8 0.4 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 EGG07904.1 - 0.023 13.8 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.17 EGG07904.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain DEAD PF00270.29 EGG07904.1 - 0.049 13.4 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.6 EGG07904.1 - 0.11 13.0 0.0 0.34 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGG07904.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EGG07904.1 - 0.12 11.9 0.1 2 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EGG07904.1 - 0.13 11.1 0.7 0.2 10.4 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Clat_adaptor_s PF01217.20 EGG07905.1 - 2e-05 24.6 0.0 2.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Carn_acyltransf PF00755.20 EGG07909.1 - 7.6e-201 668.8 0.0 8.7e-201 668.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Mito_carr PF00153.27 EGG07911.1 - 1.1e-56 188.8 1.4 5.2e-20 71.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGG07911.1 - 0.006 15.8 2.5 0.52 9.4 0.1 3.6 2 1 1 4 4 4 1 Gammaproteobacterial serine protease PrcB_C PF14343.6 EGG07911.1 - 0.019 15.1 0.2 3.2 7.9 0.1 3.2 3 0 0 3 3 3 0 PrcB C-terminal V-ATPase_G_2 PF16999.5 EGG07911.1 - 0.43 11.0 2.5 0.39 11.1 0.4 1.9 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Efg1 PF10153.9 EGG07912.1 - 1.7e-27 96.1 13.8 1.7e-27 96.1 13.8 2.1 2 0 0 2 2 2 1 rRNA-processing protein Efg1 SpoIISA_toxin PF14171.6 EGG07912.1 - 0.0099 15.6 0.7 0.013 15.2 0.7 1.3 1 0 0 1 1 1 1 Toxin SpoIISA, type II toxin-antitoxin system Fib_alpha PF08702.10 EGG07912.1 - 2.4 8.3 7.9 4.6 7.4 0.6 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family JAB PF01398.21 EGG07914.1 - 1e-15 57.7 0.0 1.7e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGG07914.1 - 9.9e-14 51.7 2.5 1.9e-13 50.8 2.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF3432 PF11914.8 EGG07914.1 - 1.3 9.3 4.0 0.81 10.0 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) SR-25 PF10500.9 EGG07915.1 - 0.011 15.4 21.0 0.024 14.3 21.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPICE PF15678.5 EGG07915.1 - 0.031 13.6 6.9 0.053 12.9 6.9 1.3 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression Bcl-2 PF00452.19 EGG07915.1 - 0.044 14.5 0.0 0.092 13.4 0.0 1.4 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family DUF755 PF05501.11 EGG07915.1 - 0.38 11.0 29.9 1.1 9.5 29.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Apt1 PF10351.9 EGG07915.1 - 0.6 8.9 7.3 0.93 8.3 7.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC106 PF15794.5 EGG07915.1 - 1.1 8.9 8.3 2.1 8.0 8.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Macoilin PF09726.9 EGG07915.1 - 1.1 7.7 7.6 1.6 7.2 7.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF1168 PF06658.12 EGG07915.1 - 1.8 8.4 13.6 3.4 7.5 13.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF4692 PF15763.5 EGG07915.1 - 3.2 8.2 9.3 8.7 6.8 9.3 1.7 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) NPR3 PF03666.13 EGG07915.1 - 3.7 6.2 8.8 6.6 5.4 8.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 EGG07916.1 - 3.5 5.8 9.7 3.6 5.7 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 EGG07916.1 - 6.1 6.5 11.3 9.8 5.8 11.3 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NHL PF01436.21 EGG07919.1 - 0.096 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 NHL repeat Peptidase_C14 PF00656.22 EGG07920.1 - 3e-61 207.5 0.0 3.8e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DAO_C PF16901.5 EGG07920.1 - 0.2 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase Ribosomal_S17_N PF16205.5 EGG07921.1 - 1.1e-33 115.4 1.8 2.1e-33 114.5 1.8 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EGG07921.1 - 2.5e-26 91.6 0.5 4.5e-26 90.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 IMS_HHH PF11798.8 EGG07922.1 - 0.023 15.0 0.0 1.6e+02 3.0 0.0 4.6 5 0 0 5 5 5 0 IMS family HHH motif Sugar_tr PF00083.24 EGG07923.1 - 6e-114 381.4 22.9 6.7e-114 381.2 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG07923.1 - 2.5e-27 95.7 30.4 2.5e-27 95.7 30.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2243 PF10002.9 EGG07923.1 - 3.8 7.6 10.1 0.077 13.1 0.9 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2243) WD40 PF00400.32 EGG07925.1 - 2.1e-37 126.4 18.4 1.4e-06 28.9 0.1 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG07925.1 - 2.7e-17 62.8 0.0 4.1e-05 23.8 0.0 4.6 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG07925.1 - 6.2e-06 26.2 0.0 0.00092 19.1 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EGG07925.1 - 0.0013 17.3 0.0 0.0024 16.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EGG07925.1 - 0.0018 17.3 0.0 0.62 9.0 0.0 3.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EGG07925.1 - 0.0046 16.6 0.1 0.064 12.8 0.1 2.4 2 1 0 2 2 2 1 PQQ-like domain Gmad1 PF10647.9 EGG07925.1 - 0.056 13.2 1.1 0.61 9.8 0.0 2.7 3 1 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.6 EGG07925.1 - 0.057 13.9 1.5 3.5 8.2 0.0 3.9 4 1 0 4 4 4 0 PQQ-like domain adh_short PF00106.25 EGG07930.1 - 9.5e-34 116.6 0.2 5.5e-13 48.8 0.0 3.1 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 EGG07930.1 - 9e-24 84.3 0.1 4e-08 33.1 0.0 3.1 3 0 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG07930.1 - 2.1e-09 37.5 0.5 0.00014 21.8 0.0 2.9 3 0 0 3 3 3 2 KR domain NAD_binding_10 PF13460.6 EGG07930.1 - 0.0092 15.9 0.1 0.033 14.1 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Exonuc_VII_S PF02609.16 EGG07932.1 - 0.0034 17.4 0.2 0.01 15.9 0.2 1.8 1 0 0 1 1 1 1 Exonuclease VII small subunit Gastrin PF00918.17 EGG07932.1 - 0.15 13.0 0.7 1 10.3 0.0 2.0 1 1 1 2 2 2 0 Gastrin/cholecystokinin family CENP-Q PF13094.6 EGG07932.1 - 2.3 8.4 9.7 7.4 6.8 9.7 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Med17 PF10156.9 EGG07933.1 - 3.4e-27 95.3 0.0 4.8e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex baeRF_family5 PF18846.1 EGG07934.1 - 0.17 12.1 1.7 0.5 10.6 1.7 1.6 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 HhH-GPD PF00730.25 EGG07935.1 - 4e-15 56.2 0.0 9.7e-15 55.0 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein BAG PF02179.16 EGG07935.1 - 0.16 12.4 0.1 0.46 11.0 0.1 1.7 1 1 0 1 1 1 0 BAG domain CTP_transf_1 PF01148.20 EGG07937.1 - 2.7e-06 27.3 2.7 3.3e-06 27.1 2.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family L_HMGIC_fpl PF10242.9 EGG07937.1 - 0.0061 16.8 0.2 0.0079 16.4 0.2 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Gemini_mov PF01708.16 EGG07937.1 - 0.02 14.6 0.1 0.043 13.6 0.1 1.6 1 0 0 1 1 1 0 Geminivirus putative movement protein Flavoprotein PF02441.19 EGG07938.1 - 2.4e-47 160.6 0.0 2.7e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein CALM_bind PF16025.5 EGG07940.1 - 0.00051 20.4 1.2 0.00051 20.4 1.2 2.7 3 0 0 3 3 3 1 Calcium-dependent calmodulin binding DWNN PF08783.11 EGG07942.1 - 6.4e-32 109.7 0.1 1.2e-31 108.7 0.1 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EGG07942.1 - 4.1e-08 32.9 6.3 1.1e-07 31.5 6.3 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 EGG07942.1 - 0.00021 21.0 12.6 0.00021 21.0 12.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG07942.1 - 0.00052 20.3 12.8 0.0012 19.1 12.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGG07942.1 - 0.00088 19.1 15.0 0.0019 18.0 15.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG07942.1 - 0.0019 18.0 10.6 0.0019 18.0 10.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 EGG07942.1 - 0.005 16.9 0.9 0.005 16.9 0.9 2.8 3 0 0 3 3 3 1 Zinc knuckle zf-UDP PF14569.6 EGG07942.1 - 0.01 15.9 2.9 0.026 14.6 2.9 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 EGG07942.1 - 0.037 13.9 7.5 0.093 12.6 7.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-CCHC_3 PF13917.6 EGG07942.1 - 0.35 10.9 3.0 0.17 11.9 0.2 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4_4 PF15227.6 EGG07942.1 - 0.49 10.6 13.8 1.1 9.5 13.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGG07942.1 - 5.2 7.0 8.7 11 5.9 8.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pox_A30L_A26L PF06086.12 EGG07943.1 - 0.25 11.0 0.0 0.33 10.6 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein DUF1712 PF08217.11 EGG07944.1 - 2.7e-10 39.4 0.0 5.2e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) DUF3446 PF11928.8 EGG07944.1 - 0.016 15.5 1.0 0.016 15.5 1.0 4.4 3 2 0 3 3 3 0 Early growth response N-terminal domain SAM_2 PF07647.17 EGG07946.1 - 0.12 12.5 0.4 10 6.3 0.0 2.5 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) CxC1 PF18802.1 EGG07948.1 - 1.3e-06 28.5 1.0 2.9e-06 27.4 1.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases UPF0227 PF05728.12 EGG07948.1 - 0.0098 15.8 0.4 0.019 14.9 0.4 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) CxC2 PF18803.1 EGG07948.1 - 0.035 14.3 0.2 0.069 13.3 0.2 1.4 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases ABC_tran_CTD PF16326.5 EGG07948.1 - 0.061 13.6 0.3 0.061 13.6 0.3 4.0 4 0 0 4 4 4 0 ABC transporter C-terminal domain DUF1660 PF07874.11 EGG07948.1 - 0.075 13.5 0.3 0.25 11.8 0.3 1.9 1 0 0 1 1 1 0 Prophage protein (DUF1660) Ssl1 PF04056.14 EGG07949.1 - 6.3e-76 254.5 0.1 1.1e-75 253.7 0.1 1.4 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 EGG07949.1 - 4.8e-12 46.5 0.0 1.5e-11 44.9 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 EGG07949.1 - 1.3e-08 34.9 13.2 1.3e-08 34.9 13.2 2.8 2 0 0 2 2 2 1 TFIIH C1-like domain Mucin PF01456.17 EGG07949.1 - 0.78 9.7 25.9 0.4 10.7 6.6 2.8 3 0 0 3 3 3 0 Mucin-like glycoprotein Dicty_REP PF05086.12 EGG07949.1 - 1.6 6.6 13.0 0.61 8.0 1.6 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein IBR PF01485.21 EGG07949.1 - 4.5 7.6 21.9 0.093 13.0 9.4 2.8 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Na_H_Exchanger PF00999.21 EGG07951.1 - 4.2e-53 180.5 50.0 6.5e-53 179.9 50.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3755 PF12579.8 EGG07951.1 - 0.025 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) Exo_endo_phos PF03372.23 EGG07952.1 - 2.5e-07 30.4 0.0 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RLL PF10036.9 EGG07952.1 - 0.073 12.9 0.0 0.073 12.9 0.0 2.6 3 0 0 3 3 3 0 RNA transcription, translation and transport factor protein CDC45 PF02724.14 EGG07952.1 - 0.42 8.8 2.8 0.74 8.0 2.7 1.4 2 0 0 2 2 2 0 CDC45-like protein Tim54 PF11711.8 EGG07952.1 - 0.61 8.8 5.6 0.78 8.5 5.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF948 PF06103.11 EGG07956.1 - 0.0096 16.2 0.3 0.019 15.2 0.3 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 EGG07956.1 - 0.012 16.1 0.1 0.028 14.9 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DNA_pol_E_B PF04042.16 EGG07957.1 - 1.2e-38 132.6 0.6 1.7e-38 132.1 0.6 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EGG07957.1 - 0.0044 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain RIX1 PF08167.12 EGG07959.1 - 0.0011 18.7 0.9 0.0018 18.1 0.9 1.3 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Lipase_GDSL PF00657.22 EGG07961.1 - 0.066 13.2 0.3 1.3 8.9 0.3 2.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Flagellin_N PF00669.20 EGG07961.1 - 0.11 12.5 0.2 6.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region 2OG-FeII_Oxy_2 PF13532.6 EGG07962.1 - 3.2e-13 50.3 0.1 3.6e-13 50.1 0.1 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nop14 PF04147.12 EGG07963.1 - 0.33 9.1 14.9 0.52 8.5 14.9 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EGG07963.1 - 0.34 10.3 12.3 0.51 9.7 12.3 1.2 1 0 0 1 1 1 0 SDA1 RNA_pol_3_Rpc31 PF11705.8 EGG07963.1 - 0.85 9.8 15.5 1.4 9.1 15.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Vfa1 PF08432.10 EGG07963.1 - 1.9 8.8 10.0 4.3 7.6 10.0 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.16 EGG07963.1 - 2 7.6 7.8 3.1 6.9 7.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.6 EGG07963.1 - 3 7.5 7.5 7.3 6.2 7.5 1.7 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EGG07963.1 - 3.7 6.8 15.9 5.8 6.1 15.9 1.2 1 0 0 1 1 1 0 NOA36 protein RhoGAP PF00620.27 EGG07964.1 - 1.5e-38 132.0 0.0 3.3e-38 130.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Pkinase PF00069.25 EGG07965.1 - 1.2e-44 152.7 0.0 2.6e-27 95.9 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG07965.1 - 1e-18 67.6 0.0 5.4e-18 65.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG07965.1 - 0.00016 21.7 0.0 0.00042 20.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG07965.1 - 0.00029 20.2 0.0 0.014 14.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like He_PIG PF05345.12 EGG07966.1 - 2.6e-09 37.1 20.5 1.3e-05 25.3 0.5 5.6 5 0 0 5 5 5 3 Putative Ig domain GPI2 PF06432.11 EGG07967.1 - 6.1e-51 173.5 5.5 2.8e-33 115.6 1.6 2.0 1 1 1 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase NCE101 PF11654.8 EGG07967.1 - 0.085 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Non-classical export protein 1 Coatomer_WDAD PF04053.14 EGG07968.1 - 2.5e-158 527.8 0.0 5.5e-158 526.7 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EGG07968.1 - 9.1e-41 137.1 4.9 3.5e-07 30.8 0.0 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG07968.1 - 5.9e-08 32.9 0.1 1.9 8.8 0.0 6.2 5 1 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Isochorismatase PF00857.20 EGG07969.1 - 2.7e-21 76.5 0.0 4.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Helicase_C PF00271.31 EGG07973.1 - 3.8e-14 53.0 0.1 7e-14 52.1 0.0 1.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Abhydrolase_6 PF12697.7 EGG07974.1 - 0.0029 18.2 0.0 0.0041 17.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGG07974.1 - 0.013 15.3 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 EGG07974.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 EGG07974.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ras PF00071.22 EGG07976.1 - 2.3e-49 167.1 0.0 2.7e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG07976.1 - 2.4e-29 102.0 0.0 3.7e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG07976.1 - 7.6e-09 35.3 0.0 1.1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG07976.1 - 0.00058 19.3 0.0 0.00068 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG07976.1 - 0.0023 18.0 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF5118 PF17162.4 EGG07976.1 - 0.0085 15.9 0.0 0.07 13.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5118) DAP3 PF10236.9 EGG07976.1 - 0.012 14.8 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 EGG07976.1 - 0.021 14.6 0.1 0.028 14.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EGG07976.1 - 0.021 14.3 0.1 0.032 13.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 EGG07976.1 - 0.028 13.6 0.5 1.2 8.2 0.1 2.5 2 1 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 EGG07976.1 - 0.033 13.7 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EGG07976.1 - 0.082 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EGG07976.1 - 0.086 12.7 0.0 10 6.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EGG07976.1 - 0.09 13.2 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain STAS PF01740.21 EGG07976.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.7 1 1 0 1 1 1 0 STAS domain RNA_helicase PF00910.22 EGG07976.1 - 0.12 12.7 0.1 0.72 10.3 0.1 2.0 1 1 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EGG07976.1 - 0.14 12.3 0.2 0.22 11.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 EGG07978.1 - 4.8 5.8 11.8 5.5 5.6 11.8 1.1 1 0 0 1 1 1 0 Presenilin Ctr PF04145.15 EGG07980.1 - 1.5e-27 97.1 1.0 1.8e-27 96.8 1.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family UCR_UQCRX_QCR9 PF05365.12 EGG07980.1 - 2.5 8.1 4.8 1.7 8.6 2.1 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Ctr PF04145.15 EGG07981.1 - 4.9e-31 108.3 0.0 5.8e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Herpes_UL36 PF03586.13 EGG07981.1 - 0.081 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Pept_S41_N PF18294.1 EGG07982.1 - 0.11 12.5 2.1 0.23 11.5 0.6 2.3 2 0 0 2 2 2 0 Peptidase S41 N-terminal domain Nha1_C PF08619.10 EGG07983.1 - 1.5 8.0 7.6 2 7.5 7.6 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus SOG2 PF10428.9 EGG07993.1 - 0.061 12.5 12.4 0.085 12.0 12.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Stc1 PF12898.7 EGG07994.1 - 0.024 15.2 1.9 0.024 15.2 1.9 1.9 1 1 1 2 2 2 0 Stc1 domain Dynamin_M PF01031.20 EGG07995.1 - 3.2e-66 223.5 0.0 5e-66 222.8 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 EGG07995.1 - 3.8e-27 94.3 1.1 7.4e-27 93.3 1.1 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain GFP PF01353.22 EGG07996.1 - 0.1 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Green fluorescent protein Sugar_tr PF00083.24 EGG07997.1 - 3.8e-111 372.1 18.1 1.4e-55 189.0 9.7 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGG07997.1 - 1.2e-28 100.1 39.7 9.9e-27 93.8 22.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 EGG07997.1 - 3.5e-05 22.9 1.2 7.4e-05 21.8 1.2 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Myosin_head PF00063.21 EGG07998.1 - 4.1e-33 114.5 0.0 4.7e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) HTH_31 PF13560.6 EGG07998.1 - 0.05 14.0 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Chitin_synth_2 PF03142.15 EGG07999.1 - 1.8e-237 789.2 0.3 2.3e-237 788.8 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 EGG07999.1 - 1.4e-13 51.3 0.0 2.2e-12 47.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 EGG07999.1 - 1.4e-12 47.6 0.2 6.9e-09 35.7 0.0 2.8 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 EGG07999.1 - 2.1e-12 47.3 3.4 4.8e-12 46.2 3.4 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGG07999.1 - 2.6e-07 30.6 0.0 0.00039 20.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGG07999.1 - 0.0074 15.8 0.0 0.52 9.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 DEK_C PF08766.11 EGG08000.1 - 4.3e-18 65.0 0.0 5.2e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 DEK C terminal domain Cornichon PF03311.14 EGG08001.1 - 1.4e-16 60.9 0.3 1.6e-16 60.7 0.3 1.0 1 0 0 1 1 1 1 Cornichon protein DUF285 PF03382.14 EGG08001.1 - 0.032 14.0 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 DUF1965 PF09248.10 EGG08001.1 - 0.13 12.1 0.1 0.16 11.8 0.1 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1965) Cornichon PF03311.14 EGG08002.1 - 2.8e-49 166.5 12.0 3.2e-49 166.3 12.0 1.0 1 0 0 1 1 1 1 Cornichon protein EI24 PF07264.11 EGG08002.1 - 0.044 14.0 7.1 0.055 13.7 7.1 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF285 PF03382.14 EGG08002.1 - 0.064 13.0 0.1 0.092 12.5 0.1 1.2 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 GPDPase_memb PF10110.9 EGG08002.1 - 7.6 5.2 16.8 0.26 10.0 4.7 2.2 1 1 1 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase MIS13 PF08202.11 EGG08003.1 - 3.4e-05 23.3 0.0 5.2e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Mis12-Mtw1 protein family Calcipressin PF04847.12 EGG08003.1 - 0.035 13.9 0.1 0.035 13.9 0.1 2.1 2 0 0 2 2 2 0 Calcipressin UPF0160 PF03690.13 EGG08004.1 - 2.3e-06 27.5 0.7 5.1e-06 26.4 0.7 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) hEGF PF12661.7 EGG08007.1 - 2.5 8.9 10.8 5.5 7.8 1.3 3.6 3 0 0 3 3 3 0 Human growth factor-like EGF SWIB PF02201.18 EGG08008.1 - 4.7e-30 103.3 0.2 7.3e-30 102.7 0.2 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 EGG08008.1 - 0.0013 18.6 0.0 0.0031 17.4 0.0 1.6 2 0 0 2 2 2 1 DEK C terminal domain Methyltransf_16 PF10294.9 EGG08009.1 - 5.6e-19 68.5 0.1 7.2e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EGG08009.1 - 3.7e-06 26.6 0.0 5.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGG08009.1 - 0.00019 20.9 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGG08009.1 - 0.027 15.2 0.1 0.059 14.1 0.0 1.7 2 1 0 2 2 2 0 Methyltransferase domain E1-E2_ATPase PF00122.20 EGG08010.1 - 6.6e-20 71.4 0.0 1.3e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGG08010.1 - 3.5e-16 60.1 0.0 2.5e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG08010.1 - 0.0081 16.2 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGG08010.1 - 0.028 14.1 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase VID27 PF08553.10 EGG08011.1 - 7.4e-110 367.3 0.1 8.4e-110 367.2 0.1 1.0 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain HIRA_B PF09453.10 EGG08011.1 - 0.2 11.5 0.3 0.2 11.5 0.3 2.2 3 0 0 3 3 3 0 HIRA B motif TraI_2 PF07514.11 EGG08012.1 - 0.063 12.2 0.0 0.07 12.1 0.0 1.1 1 0 0 1 1 1 0 Putative helicase KptA_kDCL PF18176.1 EGG08012.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain Dynactin PF12455.8 EGG08012.1 - 0.21 10.8 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Dynein associated protein FAR1 PF03101.15 EGG08015.1 - 8.8e-05 23.1 1.5 0.00021 21.9 0.6 2.1 2 0 0 2 2 2 1 FAR1 DNA-binding domain HECT_2 PF09814.9 EGG08016.1 - 4.2e-10 39.0 0.1 5.2e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Suc_Fer-like PF06999.12 EGG08017.1 - 1.3e-24 87.1 0.0 1.8e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fer2 PF00111.27 EGG08017.1 - 1.2e-07 31.5 0.4 2.4e-07 30.6 0.4 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Aldedh PF00171.22 EGG08018.1 - 6.5e-95 318.3 0.0 8.7e-95 317.9 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Complex1_30kDa PF00329.19 EGG08019.1 - 1.2e-44 151.8 0.0 1.6e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit PAH PF02671.21 EGG08019.1 - 0.053 13.7 2.1 0.2 11.8 0.0 2.6 3 1 0 3 3 3 0 Paired amphipathic helix repeat UPF0175 PF03683.13 EGG08020.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) LppX_LprAFG PF07161.13 EGG08021.1 - 0.088 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 LppX_LprAFG lipoprotein Cellulase PF00150.18 EGG08022.1 - 1.5e-07 31.2 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ETRAMP PF09716.10 EGG08022.1 - 0.0038 17.3 0.1 0.01 15.9 0.1 1.7 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) Peptidase_M28 PF04389.17 EGG08023.1 - 1.7e-26 93.1 0.0 6.8e-25 87.9 0.0 2.5 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGG08023.1 - 0.00012 21.8 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF5357 PF17310.2 EGG08023.1 - 0.16 10.5 0.9 0.38 9.3 0.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5357) DUF2627 PF11118.8 EGG08023.1 - 2.5 8.8 5.3 36 5.0 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) U1snRNP70_N PF12220.8 EGG08024.1 - 0.015 15.9 0.3 0.031 14.9 0.3 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FerB PF08150.12 EGG08024.1 - 0.098 13.3 1.9 14 6.4 0.1 2.4 2 0 0 2 2 2 0 FerB (NUC096) domain PIN_8 PF18476.1 EGG08024.1 - 0.12 12.2 5.0 0.53 10.1 4.3 1.9 1 1 1 2 2 2 0 PIN like domain DUF2433 PF10360.9 EGG08024.1 - 0.14 12.3 4.3 0.2 11.7 2.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2433) MCM_N PF14551.6 EGG08024.1 - 0.29 11.7 4.0 9.5 6.9 4.0 2.9 1 1 0 1 1 1 0 MCM N-terminal domain Mit_KHE1 PF10173.9 EGG08024.1 - 0.33 11.0 2.8 0.44 10.6 2.8 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related ZYG-11_interact PF05884.12 EGG08024.1 - 0.98 8.8 10.9 0.87 8.9 3.9 2.1 1 1 1 2 2 2 0 Interactor of ZYG-11 DUF1284 PF06935.11 EGG08025.1 - 0.078 13.4 2.4 0.36 11.3 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) DUF1829 PF08862.10 EGG08025.1 - 0.1 13.1 2.4 2.4 8.7 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF1829 Met_gamma_lyase PF06838.11 EGG08027.1 - 0.044 12.3 0.0 0.056 12.0 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase ECH_1 PF00378.20 EGG08028.1 - 5.3e-57 193.0 0.0 6.3e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGG08028.1 - 1.5e-26 93.7 0.0 3.7e-24 85.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase GrpE PF01025.19 EGG08029.1 - 2.5e-44 150.9 0.0 3.4e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 GrpE DUF536 PF04394.14 EGG08029.1 - 0.067 13.1 0.5 0.15 11.9 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF536 TB2_DP1_HVA22 PF03134.19 EGG08031.1 - 1.5e-05 24.8 7.1 1.9e-05 24.5 2.1 2.5 2 0 0 2 2 2 2 TB2/DP1, HVA22 family CHCH PF06747.13 EGG08032.1 - 0.0012 18.9 6.5 0.0012 18.9 6.5 2.3 2 0 0 2 2 2 1 CHCH domain CX9C PF16860.5 EGG08032.1 - 0.11 12.5 10.5 0.54 10.3 4.3 2.4 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 EGG08032.1 - 2.1 8.7 9.1 3.7 7.9 2.1 2.7 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 PIN_6 PF17146.4 EGG08033.1 - 3.7e-26 91.4 0.0 7.1e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EGG08033.1 - 3.6e-25 87.9 0.9 6.3e-25 87.1 0.9 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like CxC5 PF18718.1 EGG08034.1 - 6.1e-31 106.9 3.8 8.8e-31 106.4 3.8 1.2 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases zf-AN1 PF01428.16 EGG08034.1 - 0.013 15.7 0.2 0.029 14.5 0.2 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger CxC4 PF18717.1 EGG08034.1 - 0.092 12.6 0.5 0.28 11.0 0.1 1.8 1 1 1 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases PCI PF01399.27 EGG08036.1 - 4.2e-07 30.4 0.3 4.2e-07 30.4 0.3 2.6 4 0 0 4 4 4 1 PCI domain eIF3m_C_helix PF18005.1 EGG08036.1 - 1.4e-06 27.9 0.2 3e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix RPA43_OB PF17875.1 EGG08036.1 - 0.1 13.2 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I PMC2NT PF08066.12 EGG08036.1 - 4.9 7.9 9.7 6.7 7.5 0.0 4.0 5 0 0 5 5 5 0 PMC2NT (NUC016) domain Pkinase PF00069.25 EGG08037.1 - 4.1e-05 23.1 0.0 4.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain GldH_lipo PF14109.6 EGG08037.1 - 0.0031 18.3 0.2 0.0049 17.6 0.2 1.3 1 0 0 1 1 1 1 GldH lipoprotein Sld7_C PF18596.1 EGG08039.1 - 1.2e-08 34.9 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Sld7 C-terminal domain MSA-2c PF12238.8 EGG08041.1 - 0.52 10.3 6.6 0.1 12.6 3.1 1.5 1 1 1 2 2 2 0 Merozoite surface antigen 2c Tfb5 PF06331.12 EGG08042.1 - 2.5e-23 81.8 0.1 3.1e-23 81.5 0.1 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 NIF PF03031.18 EGG08043.1 - 5.5e-36 123.7 0.0 8.4e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RNase_P_pop3 PF08228.11 EGG08044.1 - 0.019 15.0 0.0 0.14 12.2 0.0 2.5 1 1 0 1 1 1 0 RNase P subunit Pop3 Adeno_E3_15_3 PF03307.14 EGG08045.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region DUF4727 PF15856.5 EGG08048.1 - 0.05 13.2 0.1 0.05 13.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) AAA PF00004.29 EGG08049.1 - 1e-56 191.0 0.0 3.2e-44 150.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EGG08049.1 - 2.8e-22 78.9 1.8 6.6e-22 77.7 1.8 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EGG08049.1 - 1.9e-13 50.0 0.0 2.8e-09 36.6 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGG08049.1 - 2e-08 34.8 6.5 0.021 15.2 0.0 4.3 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EGG08049.1 - 1.2e-06 28.9 4.4 0.029 14.7 0.4 4.4 3 2 1 4 4 3 2 AAA domain AAA_18 PF13238.6 EGG08049.1 - 1.8e-06 28.5 0.0 0.033 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGG08049.1 - 2.1e-06 27.9 0.0 0.014 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGG08049.1 - 8.9e-06 25.7 4.0 0.46 10.4 0.8 4.2 3 1 0 3 3 3 2 NACHT domain AAA_5 PF07728.14 EGG08049.1 - 1.4e-05 25.1 0.1 0.22 11.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGG08049.1 - 1.7e-05 25.0 0.0 0.0045 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EGG08049.1 - 1.9e-05 25.0 0.0 0.12 12.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Viral_helicase1 PF01443.18 EGG08049.1 - 3.6e-05 23.6 0.0 0.084 12.6 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 EGG08049.1 - 6.7e-05 22.7 0.0 0.0023 17.7 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EGG08049.1 - 0.0001 22.3 0.0 0.23 11.4 0.0 2.8 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EGG08049.1 - 0.00048 20.2 0.0 0.8 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGG08049.1 - 0.00053 19.4 0.2 0.12 11.8 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EGG08049.1 - 0.00066 20.2 0.0 0.43 11.1 0.0 3.0 2 1 1 3 3 2 1 ABC transporter Zeta_toxin PF06414.12 EGG08049.1 - 0.001 18.4 0.2 0.69 9.2 0.0 2.9 3 0 0 3 3 2 1 Zeta toxin Rad17 PF03215.15 EGG08049.1 - 0.002 18.1 0.0 0.21 11.5 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 EGG08049.1 - 0.0022 17.5 0.0 0.59 9.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 EGG08049.1 - 0.003 17.3 0.1 2.5 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGG08049.1 - 0.0035 16.9 2.0 0.35 10.4 0.0 3.8 4 0 0 4 4 4 1 AAA domain TIP49 PF06068.13 EGG08049.1 - 0.0054 16.0 0.0 0.068 12.4 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain Bac_DnaA PF00308.18 EGG08049.1 - 0.0058 16.5 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein TniB PF05621.11 EGG08049.1 - 0.012 15.0 0.0 2.5 7.5 0.0 2.8 3 0 0 3 3 3 0 Bacterial TniB protein IstB_IS21 PF01695.17 EGG08049.1 - 0.013 15.3 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein cobW PF02492.19 EGG08049.1 - 0.016 14.8 0.1 0.65 9.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EGG08049.1 - 0.025 15.0 0.2 0.15 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EGG08049.1 - 0.026 14.4 0.0 0.52 10.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGG08049.1 - 0.036 14.0 0.0 7.6 6.4 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 EGG08049.1 - 0.04 13.1 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 EGG08049.1 - 0.066 12.4 0.1 2.2 7.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 EGG08049.1 - 0.067 13.4 0.0 7 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGG08049.1 - 0.07 13.5 0.0 3.1 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGG08049.1 - 0.095 12.5 0.1 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 EGG08049.1 - 0.11 11.6 0.0 0.95 8.5 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 EGG08049.1 - 0.11 12.1 0.0 22 4.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 EGG08049.1 - 0.15 11.9 0.1 6.2 6.7 0.0 2.3 2 0 0 2 2 2 0 NTPase FXMRP1_C_core PF12235.8 EGG08055.1 - 0.44 11.2 28.9 0.15 12.7 11.9 3.0 3 0 0 3 3 3 0 Fragile X-related 1 protein core C terminal FmiP_Thoc5 PF09766.9 EGG08057.1 - 7.2e-35 120.9 9.9 9.3e-35 120.6 9.9 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Perilipin PF03036.16 EGG08057.1 - 0.0029 16.7 0.9 0.0029 16.7 0.9 1.9 1 1 1 2 2 2 1 Perilipin family DUF3958 PF13125.6 EGG08057.1 - 0.038 14.2 10.5 0.17 12.1 8.9 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) Seryl_tRNA_N PF02403.22 EGG08057.1 - 0.15 12.3 8.4 0.49 10.7 4.4 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FoP_duplication PF13865.6 EGG08057.1 - 0.19 12.3 1.5 0.35 11.5 1.5 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Mei5 PF10376.9 EGG08057.1 - 0.42 10.4 10.5 6.4 6.6 0.2 2.2 1 1 1 2 2 2 0 Double-strand recombination repair protein DUF1465 PF07323.12 EGG08057.1 - 0.45 10.4 5.0 1.9 8.3 1.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1465) Mod_r PF07200.13 EGG08057.1 - 0.86 9.7 15.0 0.4 10.8 6.1 2.8 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Casc1_N PF15927.5 EGG08057.1 - 0.96 9.1 13.7 0.28 10.8 9.4 2.1 1 1 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus RRM_1 PF00076.22 EGG08059.1 - 1.2e-12 47.4 0.0 1.4e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EGG08060.1 - 1.7e-16 59.8 0.0 2.1e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG08060.1 - 1e-05 25.4 0.0 1.3e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGG08060.1 - 1.6e-05 24.9 0.0 1.8e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 RNA binding motif RRM_7 PF16367.5 EGG08060.1 - 1.9e-05 24.7 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 EGG08060.1 - 0.00018 21.3 0.0 0.0002 21.2 0.0 1.0 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EGG08060.1 - 0.08 12.5 0.0 0.089 12.4 0.0 1.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 EGG08061.1 - 5.4e-09 36.9 2.4 5.4e-09 36.9 2.4 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Adaptin_N PF01602.20 EGG08062.1 - 3.4e-127 425.2 14.5 4.8e-127 424.7 14.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EGG08062.1 - 1.2e-40 138.2 0.1 3.7e-40 136.6 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EGG08062.1 - 1.9e-18 66.8 0.0 8.4e-18 64.7 0.0 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain PGG PF13962.6 EGG08064.1 - 0.035 13.9 0.8 0.053 13.3 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function EXS PF03124.14 EGG08064.1 - 0.04 13.3 2.2 0.044 13.1 1.5 1.4 1 1 1 2 2 2 0 EXS family Sec23_helical PF04815.15 EGG08064.1 - 0.042 13.7 0.1 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 helical domain Ribosomal_L7Ae PF01248.26 EGG08065.1 - 6.1e-27 93.2 2.1 7.7e-27 92.9 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4054 PF13262.6 EGG08066.1 - 0.17 11.9 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) NUDIX PF00293.28 EGG08067.1 - 1e-11 45.0 0.0 1.8e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Cobalamin_bind PF01122.19 EGG08068.1 - 0.014 14.3 1.1 0.016 14.1 1.1 1.1 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein TbpB_C PF17483.2 EGG08068.1 - 0.02 15.2 2.5 0.026 14.9 2.5 1.1 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B Fib_alpha PF08702.10 EGG08068.1 - 0.046 13.9 9.8 0.052 13.7 9.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MFS_1 PF07690.16 EGG08069.1 - 1.5e-19 70.2 21.2 8.9e-15 54.5 9.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 EGG08069.1 - 4.4e-12 46.0 9.9 6.1e-12 45.6 4.8 3.0 2 1 0 2 2 2 1 Nodulin-like Tetraspanin PF00335.20 EGG08069.1 - 0.00057 19.7 0.1 0.0054 16.5 0.2 2.5 2 0 0 2 2 2 1 Tetraspanin family ZYG-11_interact PF05884.12 EGG08069.1 - 2 7.8 5.9 0.15 11.5 0.6 1.8 2 0 0 2 2 2 0 Interactor of ZYG-11 Glyco_hydro_2_N PF02837.18 EGG08070.1 - 4.7e-11 42.9 0.5 1.4e-10 41.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 EGG08070.1 - 2.6e-09 36.6 0.1 2.1e-07 30.3 0.1 2.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 EGG08070.1 - 4e-09 37.1 0.0 1e-08 35.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Spore-coat_CotD PF11122.8 EGG08072.1 - 0.18 12.6 3.1 0.53 11.1 3.1 1.8 1 0 0 1 1 1 0 Inner spore coat protein D zf-CCHC PF00098.23 EGG08074.1 - 0.037 14.1 3.6 0.037 14.1 3.6 3.4 3 0 0 3 3 3 0 Zinc knuckle DUF4746 PF15928.5 EGG08078.1 - 5.8 6.2 8.2 7.2 5.9 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FOXP-CC PF16159.5 EGG08086.1 - 0.00039 21.0 3.1 0.48 11.1 0.3 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-TRAF PF02176.18 EGG08086.1 - 0.052 14.2 1.1 2.3 9.0 0.0 2.1 1 1 0 2 2 2 0 TRAF-type zinc finger zf-Di19 PF05605.12 EGG08086.1 - 0.094 13.0 0.5 0.15 12.4 0.5 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 EGG08086.1 - 0.16 12.5 0.6 0.16 12.5 0.6 2.6 3 0 0 3 3 3 0 Zinc-finger double domain IBR PF01485.21 EGG08086.1 - 0.25 11.6 4.8 2.5 8.4 4.8 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Whi5 PF08528.11 EGG08087.1 - 1.6e-06 27.6 0.4 4.4e-06 26.2 0.4 1.8 1 0 0 1 1 1 1 Whi5 like Mito_carr PF00153.27 EGG08089.1 - 1.9e-66 220.0 6.2 3.3e-23 81.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.24 EGG08090.1 - 8e-50 170.0 18.2 1e-49 169.6 18.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG08090.1 - 2.2e-20 72.9 27.6 2.2e-20 72.9 27.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.15 EGG08090.1 - 0.0087 15.0 0.1 0.0087 15.0 0.1 1.8 2 0 0 2 2 2 1 MMPL family ADK PF00406.22 EGG08091.1 - 3.3e-46 157.1 0.0 4.4e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGG08091.1 - 3.5e-35 121.4 0.0 4.5e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG08091.1 - 1.1e-10 42.2 0.0 1.4e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGG08091.1 - 0.00058 19.6 0.2 0.78 9.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 EGG08091.1 - 0.0022 18.2 0.0 0.02 15.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Na_trans_cytopl PF11933.8 EGG08091.1 - 0.083 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Cytoplasmic domain of voltage-gated Na+ ion channel Zeta_toxin PF06414.12 EGG08091.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.6 1 1 0 1 1 1 0 Zeta toxin N2227 PF07942.12 EGG08094.1 - 2.4e-78 263.1 0.0 2.7e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 EGG08094.1 - 3.3e-06 27.8 0.0 8.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG08094.1 - 3.5e-06 27.0 0.0 1.6e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG08094.1 - 0.00022 21.8 0.0 0.018 15.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG08094.1 - 0.0043 17.7 0.0 0.27 12.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG08094.1 - 0.0052 16.6 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGG08094.1 - 0.17 11.7 0.0 0.5 10.2 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Ubie_methyltran PF01209.18 EGG08094.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family a_DG1_N2 PF18424.1 EGG08095.1 - 0.12 12.5 0.2 0.36 10.9 0.1 1.8 2 0 0 2 2 2 0 Alpha-Dystroglycan N-terminal domain 2 CTP_transf_1 PF01148.20 EGG08096.1 - 0.027 14.2 0.2 0.031 14.0 0.2 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family WD40 PF00400.32 EGG08098.1 - 2.4e-20 72.5 12.9 0.0042 17.9 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG08098.1 - 0.00076 19.7 0.9 0.65 10.3 0.0 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2201_N PF13203.6 EGG08098.1 - 0.063 12.9 2.0 0.11 12.1 2.0 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain NAD_kinase PF01513.21 EGG08099.1 - 1.9e-77 260.4 0.0 2.8e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EGG08099.1 - 0.079 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain FOXP-CC PF16159.5 EGG08100.1 - 0.00087 19.9 4.1 0.48 11.1 0.2 3.2 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 EGG08100.1 - 0.12 12.8 3.8 0.15 12.5 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Mob1_phocein PF03637.17 EGG08101.1 - 1.3e-61 207.5 0.0 1.7e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family TatD_DNase PF01026.21 EGG08103.1 - 1.3e-32 113.2 0.0 1.9e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase UBA_3 PF09288.10 EGG08103.1 - 0.081 12.8 0.3 1.4 8.8 0.0 3.0 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF874 PF05917.11 EGG08105.1 - 4.5 6.2 13.1 6.1 5.8 13.1 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) SAICAR_synt PF01259.18 EGG08106.1 - 8.7e-89 297.4 0.0 1.1e-88 297.1 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase DUF4932 PF16286.5 EGG08106.1 - 0.0058 16.0 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4932) Pox_Ag35 PF03286.14 EGG08109.1 - 0.42 10.4 6.7 0.59 9.9 6.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TT_ORF2 PF02957.15 EGG08109.1 - 1.6 9.7 8.7 2.7 8.9 8.4 1.6 1 1 0 1 1 1 0 TT viral ORF2 G-patch PF01585.23 EGG08110.1 - 0.00095 19.0 0.3 0.0038 17.1 0.3 2.1 1 1 0 1 1 1 1 G-patch domain hDGE_amylase PF14701.6 EGG08113.1 - 1e-10 41.3 0.2 2.3e-10 40.2 0.2 1.5 1 1 1 2 2 2 2 Glycogen debranching enzyme, glucanotransferase domain Arf PF00025.21 EGG08115.1 - 1.7e-72 242.5 0.0 2.1e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG08115.1 - 1.6e-14 54.1 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGG08115.1 - 1.7e-11 43.9 0.5 7.4e-07 28.6 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGG08115.1 - 5.6e-11 42.3 0.0 6.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGG08115.1 - 3e-10 39.8 0.0 3.8e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGG08115.1 - 4.5e-10 39.3 0.0 5.6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG08115.1 - 0.00088 19.3 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Corona_NS8 PF12093.8 EGG08118.1 - 0.0047 17.5 0.0 0.54 10.8 0.0 2.4 2 0 0 2 2 2 2 Coronavirus NS8 protein Corona_NS8 PF12093.8 EGG08120.1 - 0.066 13.8 1.0 0.55 10.8 0.0 2.1 2 0 0 2 2 2 0 Coronavirus NS8 protein SAC3_GANP PF03399.16 EGG08121.1 - 2.2e-28 99.5 6.3 1.5e-26 93.5 6.3 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EGG08121.1 - 1.5e-06 28.3 0.8 5.3e-06 26.5 0.6 2.0 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family UPF0160 PF03690.13 EGG08123.1 - 3.6e-31 109.0 0.7 4.7e-31 108.6 0.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Alg14 PF08660.11 EGG08132.1 - 7.1e-57 192.1 0.0 9e-57 191.8 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like FXMRP1_C_core PF12235.8 EGG08136.1 - 4.8 7.8 20.9 3.1 8.4 8.2 2.4 2 1 0 2 2 2 0 Fragile X-related 1 protein core C terminal Astro_capsid_p PF12226.8 EGG08139.1 - 0.02 14.1 0.5 0.02 14.1 0.5 2.5 2 0 0 2 2 2 0 Turkey astrovirus capsid protein HR_lesion PF05514.11 EGG08140.1 - 0.0054 16.9 5.7 0.0057 16.8 4.6 1.6 1 1 0 1 1 1 1 HR-like lesion-inducing FixQ PF05545.11 EGG08140.1 - 0.074 13.0 0.6 0.074 13.0 0.6 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF4637 PF15470.6 EGG08141.1 - 0.55 9.9 5.7 0.83 9.4 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 EGG08141.1 - 1.4 6.9 5.2 1.7 6.7 5.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EGG08141.1 - 2.1 7.6 5.1 2.5 7.4 5.1 1.1 1 0 0 1 1 1 0 NOA36 protein SnoaL_2 PF12680.7 EGG08142.1 - 0.0064 17.1 0.1 0.019 15.6 0.1 1.7 2 0 0 2 2 2 1 SnoaL-like domain SnoaL_2 PF12680.7 EGG08143.1 - 0.007 17.0 0.0 0.01 16.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain PHF5 PF03660.14 EGG08144.1 - 1.9e-51 172.6 10.1 2.1e-51 172.5 10.1 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EGG08144.1 - 0.097 10.5 6.1 0.076 10.9 5.3 1.3 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EGG08144.1 - 0.87 9.7 15.8 1.4 9.0 1.7 2.9 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 EGG08144.1 - 7.6 6.9 18.6 0.29 11.5 2.5 2.8 1 1 1 2 2 2 0 C1 domain AA_permease PF00324.21 EGG08145.1 - 3.3e-52 177.7 27.7 2.2e-51 174.9 27.7 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGG08145.1 - 5.1e-18 65.1 28.2 6.9e-18 64.7 28.2 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EGG08145.1 - 1.9e-11 43.7 0.0 1.9e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Solute carrier family 12 DUF2142 PF09913.9 EGG08145.1 - 0.092 11.6 9.3 0.028 13.3 0.7 3.2 3 1 0 3 3 3 0 Predicted membrane protein (DUF2142) CAP_N PF01213.19 EGG08145.1 - 1.3 8.4 3.7 0.82 9.1 1.8 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Band_3_cyto PF07565.13 EGG08146.1 - 0.037 13.8 0.9 0.037 13.8 0.9 1.6 1 1 0 1 1 1 0 Band 3 cytoplasmic domain Kelch_5 PF13854.6 EGG08148.1 - 1.3 9.1 3.6 2.1 8.4 1.3 2.5 2 0 0 2 2 2 0 Kelch motif Acetyltransf_1 PF00583.25 EGG08149.1 - 4.7e-08 33.3 0.1 8.3e-08 32.5 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG08149.1 - 0.00051 20.0 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG08149.1 - 0.016 15.6 0.1 0.029 14.8 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L7Ae PF01248.26 EGG08150.1 - 3.9e-21 74.6 0.0 4.5e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PMM PF03332.13 EGG08151.1 - 7.4e-110 365.9 3.3 8.5e-110 365.7 3.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EGG08151.1 - 1.9e-06 27.8 0.0 1.2e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGG08151.1 - 0.00033 20.3 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.13 EGG08151.1 - 0.084 12.1 0.2 0.11 11.8 0.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF600 PF04634.12 EGG08151.1 - 0.1 12.6 1.8 2.1 8.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function, DUF600 Actin PF00022.19 EGG08152.1 - 3e-26 92.0 0.0 6.4e-19 67.8 0.0 2.6 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 EGG08152.1 - 1.8e-11 43.8 0.0 4.5e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 EGG08152.1 - 0.0011 17.9 0.0 0.035 12.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EGG08152.1 - 0.034 14.6 0.0 0.089 13.2 0.0 1.7 1 0 0 1 1 1 0 Cell division protein FtsA E1-E2_ATPase PF00122.20 EGG08153.1 - 0.0045 16.5 0.3 0.0049 16.4 0.3 1.1 1 0 0 1 1 1 1 E1-E2 ATPase DUF3678 PF12435.8 EGG08153.1 - 0.064 12.7 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) DUF4218 PF13960.6 EGG08154.1 - 4.8e-05 22.9 0.1 0.00012 21.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) CCDC-167 PF15188.6 EGG08156.1 - 0.0049 17.2 0.5 0.0092 16.3 0.5 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 TPR_16 PF13432.6 EGG08156.1 - 0.039 14.6 0.9 0.07 13.8 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG08156.1 - 0.046 14.4 0.3 0.15 12.8 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Ntox28 PF15605.6 EGG08156.1 - 0.049 13.9 0.1 0.14 12.5 0.2 1.8 2 0 0 2 2 2 0 Bacterial toxin 28 Ndc1_Nup PF09531.10 EGG08157.1 - 0.092 11.4 0.1 0.092 11.4 0.1 2.2 1 1 1 2 2 2 0 Nucleoporin protein Ndc1-Nup Chromo PF00385.24 EGG08158.1 - 3.3e-12 46.1 0.8 9.9e-12 44.6 0.8 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 EGG08158.1 - 2e-09 37.4 0.1 1e-08 35.1 0.0 2.2 2 0 0 2 2 2 1 Chromo shadow domain JAB PF01398.21 EGG08158.1 - 0.31 11.0 2.3 0.23 11.4 0.2 1.8 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Alpha_kinase PF02816.18 EGG08160.1 - 9.1e-32 110.7 0.2 1.4e-31 110.1 0.2 1.3 1 0 0 1 1 1 1 Alpha-kinase family CxC5 PF18718.1 EGG08161.1 - 6.1e-32 110.1 4.2 6.1e-32 110.1 4.2 2.2 2 0 0 2 2 2 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG08161.1 - 1.7e-20 73.0 0.7 7.5e-20 71.0 0.7 2.2 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 EGG08161.1 - 0.18 11.7 1.4 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases SNF2_N PF00176.23 EGG08164.1 - 1.8e-44 151.9 0.9 2e-44 151.8 0.9 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGG08164.1 - 2e-07 30.9 0.0 2.5e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGG08164.1 - 3e-07 30.6 0.0 3.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGG08164.1 - 0.00081 19.1 0.0 0.001 18.8 0.0 1.3 1 1 0 1 1 1 1 SWI2/SNF2 ATPase Helicase_C PF00271.31 EGG08165.1 - 4.4e-15 56.0 0.0 7.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PPDK_N PF01326.19 EGG08165.1 - 0.091 12.0 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain MIS13 PF08202.11 EGG08169.1 - 0.0079 15.5 0.4 0.012 15.0 0.4 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family TTKRSYEDQ PF10212.9 EGG08169.1 - 0.043 12.8 0.1 0.05 12.6 0.1 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Cut8 PF08559.10 EGG08172.1 - 2.6e-08 33.8 0.1 5e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein BUD22 PF09073.10 EGG08173.1 - 0.27 10.5 34.8 0.34 10.2 34.8 1.2 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.9 EGG08173.1 - 0.44 9.0 23.4 0.53 8.8 23.4 1.1 1 0 0 1 1 1 0 Macoilin family DctQ PF04290.12 EGG08174.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Caps_assemb_Wzi PF14052.6 EGG08175.1 - 0.011 14.8 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Capsule assembly protein Wzi DS PF01916.17 EGG08179.1 - 5.9e-16 58.6 0.0 6.6e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase E1_DerP2_DerF2 PF02221.15 EGG08181.1 - 6.7e-08 33.0 0.2 8.7e-08 32.7 0.2 1.2 1 0 0 1 1 1 1 ML domain Tropomyosin_1 PF12718.7 EGG08182.1 - 9.2e-45 152.3 33.1 1.1e-44 152.0 33.1 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EGG08182.1 - 1.6e-10 40.8 33.0 5.3e-06 26.0 6.6 3.0 1 1 2 3 3 3 3 Tropomyosin CENP-F_leu_zip PF10473.9 EGG08182.1 - 0.0083 16.2 33.5 0.16 12.0 7.1 3.1 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EGG08182.1 - 0.0088 16.1 2.8 0.0088 16.1 2.8 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) GAS PF13851.6 EGG08182.1 - 0.029 13.7 31.5 0.33 10.3 31.5 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CLZ PF16526.5 EGG08182.1 - 0.033 14.6 25.4 0.46 10.9 3.1 3.5 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BRE1 PF08647.11 EGG08182.1 - 0.04 14.0 30.3 0.027 14.5 17.9 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase KELK PF15796.5 EGG08182.1 - 0.051 14.0 3.4 0.051 14.0 3.4 3.6 2 2 1 3 3 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HrpB7 PF09486.10 EGG08182.1 - 0.082 13.3 22.3 0.75 10.2 4.4 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Occludin_ELL PF07303.13 EGG08182.1 - 0.19 12.5 15.6 1.4 9.7 0.4 3.2 1 1 1 3 3 3 0 Occludin homology domain DUF3450 PF11932.8 EGG08182.1 - 0.2 10.9 26.7 0.46 9.7 12.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 EGG08182.1 - 0.23 11.6 30.3 0.17 12.0 14.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 EGG08182.1 - 0.27 11.7 26.0 0.79 10.1 8.0 2.1 1 1 0 1 1 1 0 Fez1 Jnk-SapK_ap_N PF09744.9 EGG08182.1 - 0.45 10.7 31.7 0.55 10.4 19.5 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Lectin_N PF03954.14 EGG08182.1 - 0.54 10.0 12.8 0.15 11.8 2.0 2.9 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain BORCS7 PF16088.5 EGG08182.1 - 0.55 10.5 9.4 0.25 11.6 0.9 3.0 1 1 2 3 3 3 0 BLOC-1-related complex sub-unit 7 DUF724 PF05266.14 EGG08182.1 - 0.6 9.9 25.3 0.33 10.8 15.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Laminin_II PF06009.12 EGG08182.1 - 0.74 9.8 19.2 3.1 7.8 5.3 2.4 1 1 1 2 2 2 0 Laminin Domain II YscO PF07321.12 EGG08182.1 - 0.89 9.5 29.2 0.21 11.5 8.3 3.3 1 1 2 3 3 3 0 Type III secretion protein YscO DHR10 PF18595.1 EGG08182.1 - 0.98 9.5 33.5 5.3 7.1 15.8 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain COG2 PF06148.11 EGG08182.1 - 1.3 9.1 19.4 1.7 8.7 0.7 2.9 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 EGG08182.1 - 1.9 9.0 10.7 1.1 9.7 1.0 3.0 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein Cob_adeno_trans PF01923.18 EGG08182.1 - 2.8 8.0 11.0 7.9 6.6 10.5 1.7 1 1 0 1 1 1 0 Cobalamin adenosyltransferase APG6_N PF17675.1 EGG08182.1 - 3 8.4 40.4 16 6.1 23.8 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region FliD_C PF07195.12 EGG08182.1 - 3.2 7.1 17.0 0.87 9.0 0.7 3.0 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF4094 PF13334.6 EGG08182.1 - 3.5 8.1 18.1 0.19 12.2 3.8 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) DUF2730 PF10805.8 EGG08182.1 - 3.7 7.7 14.9 0.41 10.8 2.7 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) SNARE PF05739.19 EGG08182.1 - 3.9 7.5 5.6 7 6.7 0.3 3.0 4 0 0 4 4 3 0 SNARE domain TPR_MLP1_2 PF07926.12 EGG08182.1 - 4.5 7.4 36.5 1.7 8.7 7.4 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.6 EGG08182.1 - 4.6 6.7 28.5 0.064 12.8 16.2 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 EGG08182.1 - 4.7 6.0 31.6 5.5 5.8 13.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein T3SSipB PF16535.5 EGG08182.1 - 4.8 7.6 23.0 8.4e+02 0.4 23.0 2.1 1 1 0 1 1 1 0 Type III cell invasion protein SipB HalX PF08663.10 EGG08182.1 - 5.4 7.4 23.2 3.8 7.9 1.1 4.1 2 1 1 3 3 3 0 HalX domain ADIP PF11559.8 EGG08182.1 - 5.6 7.0 31.6 2.3 8.3 13.6 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HisKA_3 PF07730.13 EGG08182.1 - 5.7 7.5 11.8 4.2 8.0 4.0 3.3 2 1 1 3 3 3 0 Histidine kinase ERM PF00769.19 EGG08182.1 - 8.2 6.2 37.5 9.4 6.0 20.4 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CHDCT2 PF08074.11 EGG08182.1 - 8.3 6.6 12.7 1.4 9.0 5.5 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Acyl-CoA_dh_2 PF08028.11 EGG08182.1 - 8.3 6.7 11.4 13 6.0 5.7 2.5 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF4472 PF14739.6 EGG08182.1 - 9.3 7.0 25.4 4.6 8.0 10.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) RNase_PH PF01138.21 EGG08183.1 - 5.5e-19 69.0 0.0 8.6e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RRM_1 PF00076.22 EGG08186.1 - 1.4e-15 56.9 0.0 1.8e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGG08186.1 - 0.0017 18.4 0.0 0.0023 17.9 0.0 1.3 1 1 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 EGG08186.1 - 0.047 13.7 0.1 0.12 12.5 0.1 1.7 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EGG08186.1 - 0.082 12.5 0.0 0.11 12.2 0.0 1.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAS2 PF02187.17 EGG08189.1 - 0.004 17.2 0.0 0.03 14.4 0.0 2.2 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain PBP PF01161.20 EGG08191.1 - 4.8e-07 30.1 0.0 8.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Alpha_GJ PF03229.13 EGG08191.1 - 6.4 7.4 12.4 0.16 12.5 4.9 2.1 3 0 0 3 3 3 0 Alphavirus glycoprotein J DHO_dh PF01180.21 EGG08192.1 - 5.6e-93 311.4 0.0 7.8e-93 310.9 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EGG08192.1 - 0.00023 20.3 0.9 0.019 14.0 2.1 2.7 2 1 0 2 2 2 1 FMN-dependent dehydrogenase ExbD PF02472.16 EGG08192.1 - 0.081 13.1 0.7 0.22 11.7 0.0 2.0 2 1 1 3 3 3 0 Biopolymer transport protein ExbD/TolR Amidase PF01425.21 EGG08195.1 - 1.7e-110 370.1 0.0 1.9e-110 369.9 0.0 1.0 1 0 0 1 1 1 1 Amidase CxC1 PF18802.1 EGG08198.1 - 6.3e-33 113.0 1.0 1.4e-32 111.9 1.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG08198.1 - 0.00012 22.2 0.9 0.00029 20.9 0.9 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG08198.1 - 0.013 15.4 1.8 0.053 13.4 1.8 2.1 1 1 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases zf-3CxxC PF13695.6 EGG08198.1 - 0.3 11.6 12.6 0.15 12.6 1.3 3.3 3 0 0 3 3 3 0 Zinc-binding domain zf-3CxxC_2 PF17180.4 EGG08198.1 - 5.5 7.8 6.9 1.1 10.1 2.1 2.3 2 0 0 2 2 2 0 Zinc-binding domain Svf1 PF08622.10 EGG08201.1 - 6e-45 153.2 0.0 9e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 EGG08201.1 - 3.6e-39 134.2 0.0 6.3e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain DUF4587 PF15248.6 EGG08203.1 - 0.44 11.4 2.3 2.6 8.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) YqfQ PF14181.6 EGG08203.1 - 1.4 9.1 4.2 2.6 8.2 4.2 1.3 1 0 0 1 1 1 0 YqfQ-like protein MTHFR PF02219.17 EGG08206.1 - 5.7e-111 370.4 0.0 8.4e-111 369.9 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF4661 PF15576.6 EGG08210.1 - 0.17 11.8 2.1 8.4 6.2 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4661) CK_II_beta PF01214.18 EGG08211.1 - 2e-82 275.4 0.0 2.3e-82 275.2 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Glutaredoxin PF00462.24 EGG08213.1 - 5.9e-17 61.6 0.0 8.3e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Ribosomal_S4e PF00900.20 EGG08215.1 - 1.8e-36 123.9 0.6 2.9e-36 123.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 EGG08215.1 - 1.7e-18 66.0 0.2 3.3e-18 65.1 0.2 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EGG08215.1 - 3.2e-18 65.5 3.3 5.3e-18 64.8 3.3 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EGG08215.1 - 1.8e-07 30.7 0.9 5e-07 29.3 0.0 2.2 3 0 0 3 3 3 1 S4 domain KOW PF00467.29 EGG08215.1 - 0.00014 21.7 1.5 0.00055 19.8 1.5 2.1 1 0 0 1 1 1 1 KOW motif ECH_2 PF16113.5 EGG08216.1 - 9.7e-100 334.3 0.0 1.1e-99 334.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGG08216.1 - 1.2e-24 87.0 0.0 1.9e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF2754 PF10953.8 EGG08216.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Fungal_trans PF04082.18 EGG08218.1 - 5.4e-33 114.2 1.6 1e-32 113.2 1.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGG08218.1 - 2.6e-08 33.8 7.6 5.1e-08 32.9 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ELMO_CED12 PF04727.13 EGG08221.1 - 2.6e-25 89.5 0.5 5.9e-25 88.4 0.5 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 EGG08221.1 - 1.5e-23 83.8 0.1 3.9e-23 82.4 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 EGG08221.1 - 0.0052 16.7 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) LRRC37AB_C PF14914.6 EGG08223.1 - 0.017 15.0 0.3 0.029 14.3 0.3 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain CAP PF00188.26 EGG08224.1 - 2.4e-17 64.0 1.1 2.4e-17 64.0 1.1 2.3 2 2 0 2 2 2 1 Cysteine-rich secretory protein family Hce2 PF14856.6 EGG08224.1 - 0.062 13.6 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor ABC_membrane PF00664.23 EGG08225.1 - 4.9e-79 265.8 33.8 1.7e-42 146.0 11.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGG08225.1 - 1.3e-47 161.7 4.0 6.7e-26 91.4 0.2 3.2 4 0 0 4 4 3 2 ABC transporter SMC_N PF02463.19 EGG08225.1 - 2.4e-11 43.5 0.0 3.8e-06 26.5 0.0 4.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain MeaB PF03308.16 EGG08225.1 - 0.00016 20.7 0.6 0.12 11.4 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EGG08225.1 - 0.00023 21.2 2.8 0.14 12.3 0.4 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG08225.1 - 0.00026 21.0 2.0 0.033 14.1 0.2 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EGG08225.1 - 0.0018 17.9 0.2 1.9 8.0 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGG08225.1 - 0.0027 17.4 3.3 1.3 8.8 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG08225.1 - 0.0036 17.7 1.6 0.28 11.6 0.3 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGG08225.1 - 0.0053 17.0 0.3 8 6.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 EGG08225.1 - 0.045 13.8 5.9 1.7 8.7 0.6 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 EGG08225.1 - 0.047 13.4 0.0 5.7 6.6 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein T2SSE PF00437.20 EGG08225.1 - 0.063 12.3 1.2 1.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 EGG08225.1 - 0.065 13.3 3.3 0.14 12.2 0.9 2.4 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.6 EGG08225.1 - 0.07 13.4 0.6 2 8.7 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 EGG08225.1 - 0.079 12.5 1.3 8 5.9 0.0 2.8 3 0 0 3 3 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGG08225.1 - 0.12 12.6 0.2 29 4.8 0.1 3.4 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.12 EGG08225.1 - 0.14 11.4 1.2 1.3 8.3 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 EGG08225.1 - 0.16 10.8 2.1 3.1 6.6 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_21 PF13304.6 EGG08225.1 - 0.27 11.0 0.9 3.4 7.4 0.1 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 EGG08225.1 - 0.29 10.4 1.2 13 5.1 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EGG08225.1 - 1.9 8.9 7.1 3.5 8.1 0.5 2.8 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EGG08225.1 - 2.5 7.8 6.9 4.3 7.0 0.0 3.5 4 0 0 4 4 4 0 AAA domain Ribosomal_S10 PF00338.22 EGG08228.1 - 0.073 13.3 0.1 0.073 13.3 0.1 1.6 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e DUF4672 PF15716.5 EGG08231.1 - 0.21 11.2 0.5 0.33 10.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) Drc1-Sld2 PF11719.8 EGG08231.1 - 0.29 10.6 1.2 0.32 10.5 1.2 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Dscam_C PF12355.8 EGG08232.1 - 0.052 14.5 1.6 0.12 13.3 1.6 1.6 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Cadherin_tail PF15974.5 EGG08232.1 - 0.15 12.4 2.1 0.48 10.7 2.0 1.9 2 0 0 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region CxC1 PF18802.1 EGG08236.1 - 0.041 14.0 0.1 0.079 13.1 0.1 1.5 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases GP24_25 PF17388.2 EGG08236.1 - 0.093 12.7 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 COX5B PF01215.19 EGG08240.1 - 1.2e-38 131.7 0.0 1.7e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 EGG08240.1 - 0.036 14.1 1.6 0.058 13.5 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger domain tRNA_Me_trans PF03054.16 EGG08241.1 - 1.2e-93 313.7 0.0 1.4e-93 313.6 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ATP_bind_3 PF01171.20 EGG08241.1 - 0.0039 17.0 0.2 0.0088 15.8 0.2 1.7 1 1 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 EGG08241.1 - 0.031 14.0 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase ThiI PF02568.14 EGG08241.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 EGG08241.1 - 0.094 11.8 0.2 0.21 10.7 0.2 1.7 1 1 0 1 1 1 0 NAD synthase DnaJ-X PF14308.6 EGG08242.1 - 5.4e-57 192.6 0.1 9.7e-57 191.8 0.1 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGG08242.1 - 1.5e-19 69.9 0.3 1.2e-18 66.9 0.2 2.4 2 0 0 2 2 2 1 DnaJ domain Mito_fiss_reg PF05308.11 EGG08242.1 - 0.043 13.9 5.4 0.083 13.0 5.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator AAA_2 PF07724.14 EGG08243.1 - 3.8e-37 128.0 0.0 5.3e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGG08243.1 - 6.7e-05 23.3 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGG08243.1 - 0.0003 20.8 0.0 0.0011 18.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 EGG08243.1 - 0.005 16.9 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 EGG08243.1 - 0.024 14.3 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Na_Ca_ex PF01699.24 EGG08244.1 - 6e-38 130.2 40.4 8e-19 68.1 15.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein RNA_pol_Rpo13 PF12136.8 EGG08244.1 - 0.036 14.0 3.2 0.07 13.0 3.2 1.4 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain RICTOR_phospho PF14665.6 EGG08246.1 - 0.19 12.1 1.2 0.39 11.1 1.2 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site DUF3496 PF12001.8 EGG08249.1 - 0.045 14.1 0.3 0.045 14.1 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) SMYLE_N PF18615.1 EGG08249.1 - 8.3 5.9 10.7 11 5.5 10.7 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Peptidase_C54 PF03416.19 EGG08259.1 - 5.4e-14 52.3 0.0 6.2e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 MLD PF11647.8 EGG08259.1 - 0.09 13.1 2.1 0.13 12.6 1.4 1.6 2 0 0 2 2 2 0 Membrane Localization Domain TrmE_N PF10396.9 EGG08260.1 - 6.4e-27 94.2 0.0 1.6e-25 89.6 0.0 2.4 2 1 0 2 2 2 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 EGG08260.1 - 7.4e-20 72.0 0.0 9.7e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 EGG08260.1 - 5.2e-16 58.7 0.0 1.4e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG08260.1 - 1.2e-05 24.9 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGG08260.1 - 0.00017 21.7 0.0 0.00037 20.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 EGG08260.1 - 0.045 13.7 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF2420 PF10336.9 EGG08262.1 - 2e-10 40.6 0.0 7.1e-10 38.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2420) SLAC1 PF03595.17 EGG08265.1 - 4.4e-53 180.7 44.1 5e-53 180.5 44.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel FAR1 PF03101.15 EGG08266.1 - 0.0024 18.5 0.0 0.0044 17.7 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Peptidase_C65 PF10275.9 EGG08266.1 - 0.0041 16.6 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain Myc-LZ PF02344.15 EGG08268.1 - 0.056 13.5 5.6 0.18 11.9 5.6 1.9 1 0 0 1 1 1 0 Myc leucine zipper domain Statherin PF03875.13 EGG08268.1 - 0.26 11.4 2.8 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Statherin Trehalose_PPase PF02358.16 EGG08269.1 - 3.3e-39 134.4 0.2 4.5e-37 127.4 0.2 2.1 1 1 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EGG08269.1 - 1.3e-06 28.4 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cutinase PF01083.22 EGG08270.1 - 9.3e-25 87.6 0.1 1.2e-24 87.3 0.1 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_8 PF06259.12 EGG08270.1 - 0.0011 18.6 0.1 0.016 14.9 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase PE-PPE PF08237.11 EGG08270.1 - 0.0022 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 EGG08270.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Hydrolase_4 PF12146.8 EGG08270.1 - 0.16 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Rad51 PF08423.11 EGG08271.1 - 7.2e-10 38.6 0.0 7.6e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 HHH_5 PF14520.6 EGG08271.1 - 5.2e-05 23.8 0.1 0.00022 21.8 0.2 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_4 PF14490.6 EGG08271.1 - 0.068 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain LPAM_1 PF08139.12 EGG08272.1 - 0.031 14.8 0.0 0.061 13.8 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site NOC3p PF07540.11 EGG08274.1 - 2.6e-27 95.1 0.0 8.2e-27 93.5 0.0 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 EGG08274.1 - 3.5e-18 66.2 0.1 3.5e-17 63.0 0.0 2.7 3 0 0 3 3 3 1 CBF/Mak21 family Histone PF00125.24 EGG08274.1 - 5 7.5 9.0 0.4 11.1 1.4 2.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TAN PF11640.8 EGG08275.1 - 1.6e-22 80.2 3.0 5.4e-22 78.5 0.7 2.9 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair HEAT PF02985.22 EGG08275.1 - 0.0075 16.4 0.1 3 8.4 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat zf-HC5HC2H_2 PF13832.6 EGG08275.1 - 0.11 12.7 2.8 0.29 11.3 1.3 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain PI3_PI4_kinase PF00454.27 EGG08276.1 - 1.2e-27 97.4 0.7 3.5e-24 86.0 0.7 3.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PNP_UDP_1 PF01048.20 EGG08277.1 - 1e-11 44.6 0.1 9.9e-09 34.8 0.0 2.2 1 1 1 2 2 2 2 Phosphorylase superfamily COG4 PF08318.12 EGG08277.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 COG4 transport protein Pmp3 PF01679.17 EGG08278.1 - 1.4e-25 89.2 8.0 1.5e-25 89.1 8.0 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF872 PF05915.12 EGG08278.1 - 0.18 12.0 0.9 0.2 11.8 0.9 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) zf-NOSIP PF15906.5 EGG08279.1 - 3.2e-11 43.2 0.1 7.4e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 EGG08279.1 - 1.8e-08 34.1 17.5 6.6e-06 25.9 9.8 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG08279.1 - 2.4e-08 33.7 18.8 0.0003 20.6 1.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG08279.1 - 7.9e-07 28.8 18.4 5.3e-05 23.0 7.5 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGG08279.1 - 1.6e-06 28.0 13.3 0.0038 17.2 4.4 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 EGG08279.1 - 8.1e-06 26.1 18.7 0.0014 18.9 9.1 2.4 2 0 0 2 2 2 2 Ring finger domain Rtf2 PF04641.12 EGG08279.1 - 1.7e-05 24.3 7.3 0.00032 20.2 2.1 2.5 3 0 0 3 3 3 2 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 EGG08279.1 - 8.9e-05 22.2 19.6 0.011 15.5 2.0 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG08279.1 - 0.00012 22.0 10.9 0.00012 22.0 10.9 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGG08279.1 - 0.00033 20.7 13.1 0.046 13.9 5.9 2.9 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 EGG08279.1 - 0.021 14.7 6.1 0.021 14.7 6.1 1.8 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EGG08279.1 - 0.24 11.6 14.9 3.2 8.0 10.1 3.1 3 1 0 3 3 3 0 FYVE zinc finger zf-RING_4 PF14570.6 EGG08279.1 - 0.32 10.8 17.6 0.037 13.8 6.4 3.3 2 2 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF2616 PF11077.8 EGG08279.1 - 2.7 7.6 5.1 0.47 10.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) DZR PF12773.7 EGG08279.1 - 7.5 6.7 16.9 14 5.8 11.1 3.2 2 1 1 3 3 3 0 Double zinc ribbon Sec6 PF06046.13 EGG08280.1 - 1.7e-22 79.5 0.4 2.9e-22 78.8 0.4 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 EGG08280.1 - 7.2e-05 21.9 3.0 0.0036 16.3 0.6 2.2 2 0 0 2 2 2 2 Vps53-like, N-terminal SKA2 PF16740.5 EGG08280.1 - 0.029 14.1 8.0 1.4 8.7 1.0 3.4 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF1664 PF07889.12 EGG08280.1 - 0.58 10.2 5.7 0.56 10.3 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Sec6 PF06046.13 EGG08281.1 - 3.1e-15 55.6 0.2 3.5e-15 55.4 0.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 F-box-like PF12937.7 EGG08287.1 - 3.1e-11 43.0 1.7 6e-11 42.1 1.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG08287.1 - 2.5e-06 27.2 1.3 6.3e-06 25.9 1.3 1.7 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 EGG08287.1 - 0.024 14.2 0.2 0.06 12.9 0.0 1.6 2 0 0 2 2 2 0 F-box NUC173 PF08161.12 EGG08288.1 - 6.2e-42 143.6 0.6 4e-40 137.6 0.1 2.6 2 0 0 2 2 2 2 NUC173 domain DUF5407 PF17401.2 EGG08289.1 - 0.003 17.8 1.4 0.0059 16.8 0.2 1.9 1 1 1 2 2 2 1 Family of unknown function (DUF5407) RNA_pol_Rpb4 PF03874.16 EGG08290.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb4 Maf PF02545.14 EGG08293.1 - 2.3e-41 141.4 0.0 2.7e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein RPAP3_C PF13877.6 EGG08293.1 - 0.071 13.7 0.1 0.18 12.4 0.0 1.7 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 Rapsyn_N PF10579.9 EGG08293.1 - 0.11 12.6 0.0 22 5.3 0.0 2.3 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region SAM_1 PF00536.30 EGG08294.1 - 2.3e-10 40.8 0.1 5.1e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box PF00505.19 EGG08294.1 - 1.2e-08 35.2 0.0 3.2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box SAM_2 PF07647.17 EGG08294.1 - 2.4e-07 30.7 0.5 6.2e-07 29.4 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 EGG08294.1 - 4.1e-06 27.3 0.1 1.4e-05 25.5 0.1 2.0 2 0 0 2 2 2 1 HMG-box domain DNA_pol_E_B PF04042.16 EGG08295.1 - 4.7e-40 137.2 0.0 8.7e-40 136.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EGG08295.1 - 4.3e-36 123.9 0.1 7.8e-36 123.1 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain zf-H2C2_2 PF13465.6 EGG08296.1 - 3.6e-05 24.0 0.4 3.6e-05 24.0 0.4 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGG08296.1 - 0.0011 19.3 7.6 0.0037 17.6 0.7 4.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type DUF4824 PF16106.5 EGG08296.1 - 0.0019 17.5 0.3 0.0029 16.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4824) zf-C2H2_4 PF13894.6 EGG08296.1 - 0.086 13.7 0.8 0.086 13.7 0.8 4.9 8 0 0 8 8 8 0 C2H2-type zinc finger KIX_2 PF16987.5 EGG08297.1 - 0.24 11.4 4.9 23 5.1 0.6 4.0 2 1 1 3 3 3 0 KIX domain Pkinase PF00069.25 EGG08298.1 - 1.5e-66 224.4 0.0 2.2e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG08298.1 - 9.6e-43 146.3 0.0 1.7e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EGG08298.1 - 2.2e-20 72.8 0.1 7.5e-20 71.0 0.1 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EGG08298.1 - 4.3e-07 29.1 0.7 4e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGG08298.1 - 0.00011 21.7 0.0 0.00023 20.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG08298.1 - 0.12 11.7 0.1 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG08298.1 - 0.14 12.0 0.1 2 8.3 0.3 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4859 PF16151.5 EGG08300.1 - 0.036 13.9 2.0 0.09 12.7 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) SDA1 PF05285.12 EGG08301.1 - 2.1 7.7 12.9 2.9 7.2 12.9 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGG08301.1 - 6.4 4.8 13.3 8.6 4.4 13.3 1.1 1 0 0 1 1 1 0 Nop14-like family COesterase PF00135.28 EGG08302.1 - 0.0075 15.2 0.0 0.0091 14.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family RCC1_2 PF13540.6 EGG08304.1 - 0.0058 16.4 3.7 0.061 13.1 0.1 3.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat BACON PF13004.7 EGG08304.1 - 0.031 14.3 0.0 0.084 12.9 0.0 1.6 2 0 0 2 2 2 0 Putative binding domain, N-terminal DUF3398 PF11878.8 EGG08306.1 - 0.015 15.7 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) AGOG PF09171.10 EGG08306.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase CAP PF00188.26 EGG08311.1 - 3.7e-19 69.8 0.3 3.7e-19 69.8 0.3 2.1 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Cu-oxidase_3 PF07732.15 EGG08312.1 - 8.1e-42 142.0 0.9 2.8e-39 133.8 0.2 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG08312.1 - 2.5e-34 118.0 1.8 3.2e-29 101.4 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGG08312.1 - 2.8e-23 82.8 0.0 1.5e-22 80.4 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Aconitase PF00330.20 EGG08313.1 - 1.8e-110 370.1 0.0 2e-109 366.7 0.0 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGG08313.1 - 7.1e-22 78.1 0.0 8.2e-21 74.7 0.0 2.3 1 1 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 EGG08313.1 - 0.0012 17.7 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Tim44 PF04280.15 EGG08314.1 - 3e-31 108.5 0.0 7.3e-31 107.3 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain XRN_N PF03159.18 EGG08314.1 - 0.055 12.9 1.8 0.17 11.3 1.8 1.8 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus SR-25 PF10500.9 EGG08314.1 - 7.7 6.0 17.6 0.32 10.6 8.5 2.6 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein COesterase PF00135.28 EGG08315.1 - 3e-64 217.7 0.0 8.3e-63 213.0 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Trp_syntA PF00290.20 EGG08316.1 - 1.7e-82 276.2 0.1 2.3e-82 275.8 0.1 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EGG08316.1 - 3.3e-24 85.8 0.5 6.4e-24 84.9 0.5 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trp_syntA PF00290.20 EGG08317.1 - 4.7e-82 274.7 0.9 6e-82 274.4 0.1 1.5 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 EGG08317.1 - 5.2e-44 150.8 2.6 8.7e-44 150.1 2.6 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme EPOP PF15223.6 EGG08318.1 - 5.5 6.2 5.7 9 5.5 5.7 1.2 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein 7tm_1 PF00001.21 EGG08319.1 - 0.024 14.0 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Glyco_transf_22 PF03901.17 EGG08320.1 - 3.3e-26 92.5 14.6 4.4e-26 92.1 14.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ribosomal_S11 PF00411.19 EGG08321.1 - 2.5e-46 156.6 1.5 3.2e-46 156.3 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EGG08321.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) PAS_4 PF08448.10 EGG08322.1 - 0.057 13.7 2.5 0.07 13.4 2.2 1.4 1 1 0 1 1 1 0 PAS fold 4HBT PF03061.22 EGG08323.1 - 4.8e-05 23.6 0.0 0.54 10.6 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily SOTI PF17079.5 EGG08323.1 - 0.026 14.9 0.0 0.074 13.5 0.0 1.7 1 0 0 1 1 1 0 Male-specific protein scotti DnaJ PF00226.31 EGG08324.1 - 1.3e-12 47.7 3.1 1.4e-12 47.5 0.1 2.6 2 0 0 2 2 2 1 DnaJ domain RVT_3 PF13456.6 EGG08325.1 - 1e-07 31.8 0.0 3e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like RVT_thumb PF06817.14 EGG08325.1 - 0.18 11.6 0.6 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase thumb domain CorA PF01544.18 EGG08326.1 - 1.2e-25 90.4 1.3 2.5e-18 66.4 0.2 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF1198 PF06711.11 EGG08326.1 - 0.018 15.1 0.1 0.46 10.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) Ribosomal_L35Ae PF01247.18 EGG08328.1 - 1.4e-41 140.5 0.2 1.6e-41 140.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae Methyltransf_20 PF12147.8 EGG08328.1 - 0.095 11.8 0.0 0.097 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Rep_fac_C PF08542.11 EGG08331.1 - 7.4e-22 77.6 0.0 2.7e-21 75.8 0.0 2.0 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EGG08331.1 - 3.9e-18 66.2 0.0 6.8e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGG08331.1 - 3e-14 53.1 0.0 2e-11 43.9 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EGG08331.1 - 1.6e-10 41.3 0.0 9e-10 38.8 0.0 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 EGG08331.1 - 1.3e-06 28.4 3.3 6.1e-05 22.9 0.1 2.7 1 1 2 3 3 3 1 AAA domain AAA_14 PF13173.6 EGG08331.1 - 5.3e-06 26.5 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGG08331.1 - 1.7e-05 25.1 0.1 0.0092 16.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGG08331.1 - 2.4e-05 23.6 0.0 3.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_assoc_2 PF16193.5 EGG08331.1 - 5.2e-05 23.5 0.0 0.00016 21.9 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_16 PF13191.6 EGG08331.1 - 5.4e-05 23.6 0.0 0.00025 21.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGG08331.1 - 6.6e-05 22.7 0.0 0.00015 21.5 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EGG08331.1 - 9.3e-05 22.2 0.0 0.00025 20.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EGG08331.1 - 0.00037 20.5 0.0 0.022 14.8 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 EGG08331.1 - 0.0005 19.9 0.1 0.0014 18.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGG08331.1 - 0.00082 19.7 0.1 0.029 14.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EGG08331.1 - 0.0012 18.7 0.0 0.0033 17.2 0.0 1.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.13 EGG08331.1 - 0.0016 18.3 0.1 0.0037 17.1 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 EGG08331.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGG08331.1 - 0.0028 17.2 0.1 0.009 15.5 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 EGG08331.1 - 0.0029 17.6 0.0 0.0093 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 EGG08331.1 - 0.0032 16.9 0.0 0.7 9.3 0.0 2.4 1 1 0 2 2 2 1 Bacterial TniB protein DEAD PF00270.29 EGG08331.1 - 0.0059 16.4 0.1 0.15 11.8 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase RNA_helicase PF00910.22 EGG08331.1 - 0.011 16.1 0.2 0.092 13.1 0.0 2.5 3 0 0 3 3 2 0 RNA helicase Sigma54_activat PF00158.26 EGG08331.1 - 0.018 14.8 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.13 EGG08331.1 - 0.021 14.1 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 EGG08331.1 - 0.027 13.9 0.0 0.32 10.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGG08331.1 - 0.044 14.0 0.0 0.089 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGG08331.1 - 0.05 13.3 0.0 0.15 11.8 0.0 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EGG08331.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGG08331.1 - 0.067 13.7 0.3 0.2 12.2 0.1 2.0 1 1 1 2 2 1 0 AAA domain MCM PF00493.23 EGG08331.1 - 0.084 12.0 0.0 0.16 11.1 0.0 1.4 1 1 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 EGG08331.1 - 0.19 12.2 0.7 1.3 9.6 0.0 2.6 3 2 0 3 3 2 0 ABC transporter Cytochrom_C1 PF02167.15 EGG08332.1 - 4.5e-97 324.1 0.0 5.7e-97 323.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EGG08332.1 - 0.0016 18.7 0.0 0.0032 17.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EGG08332.1 - 0.043 15.0 0.1 0.17 13.0 0.1 2.1 2 1 0 2 2 2 0 Cytochrome c Glyco_hydro_38N PF01074.22 EGG08334.1 - 3.3e-74 249.8 0.1 5.6e-74 249.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGG08334.1 - 8.3e-52 176.4 0.0 1.4e-51 175.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGG08334.1 - 5.7e-29 100.1 0.1 1.2e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EGG08334.1 - 1.8e-06 28.0 0.0 3.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 EGG08334.1 - 0.00085 18.6 0.0 0.0018 17.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Med8 PF10232.9 EGG08335.1 - 0.71 9.4 10.9 0.31 10.6 3.1 2.2 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Cpn10 PF00166.21 EGG08335.1 - 0.95 9.6 7.0 0.21 11.7 2.8 2.0 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit Glyco_H_20C_C PF18088.1 EGG08336.1 - 3.7e-57 193.3 1.9 4.5e-57 193.1 0.7 1.7 2 0 0 2 2 2 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 EGG08336.1 - 2.2e-12 47.0 0.3 4.5e-11 42.7 0.3 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain PBP PF01161.20 EGG08337.1 - 2.1e-08 34.5 0.0 3.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP PF01161.20 EGG08338.1 - 4e-09 36.9 0.2 7e-09 36.1 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein p450 PF00067.22 EGG08341.1 - 5e-70 236.5 0.0 6.1e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 gag-asp_proteas PF13975.6 EGG08342.1 - 0.00026 21.5 0.0 0.0007 20.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGG08342.1 - 0.066 13.9 0.0 0.19 12.4 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease RBD PF02196.15 EGG08344.1 - 0.11 12.6 0.0 25 5.0 0.0 2.5 2 0 0 2 2 2 0 Raf-like Ras-binding domain DUF2408 PF10303.9 EGG08346.1 - 1.1e-51 174.9 2.7 4.6e-37 127.6 0.0 4.4 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) DUF4764 PF15961.5 EGG08346.1 - 0.11 11.2 0.3 0.15 10.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) DUF2015 PF09435.10 EGG08347.1 - 4.6e-18 65.1 0.1 5.3e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Holin_BhlA PF10960.8 EGG08348.1 - 0.0014 18.5 0.2 0.0014 18.5 0.2 2.2 2 0 0 2 2 2 1 BhlA holin family TPR_12 PF13424.6 EGG08349.1 - 0.00016 21.9 0.1 0.79 10.0 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGG08349.1 - 0.00085 18.7 1.0 0.0014 18.0 0.1 1.8 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.17 EGG08349.1 - 0.0031 17.5 0.0 12 6.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG08349.1 - 0.015 15.1 0.1 8.9 6.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NifQ PF04891.12 EGG08349.1 - 0.2 12.0 0.6 0.52 10.6 0.2 1.9 1 1 0 1 1 1 0 NifQ Glyco_transf_24 PF18404.1 EGG08350.1 - 6.6e-144 478.2 1.6 9.7e-144 477.7 1.6 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EGG08350.1 - 9.8e-53 179.7 0.0 6.7e-52 177.0 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EGG08350.1 - 5.8e-33 113.7 0.1 1.1e-31 109.6 0.0 3.0 4 0 0 4 4 4 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EGG08350.1 - 7.2e-31 106.5 0.0 1.4e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 EGG08350.1 - 2e-26 93.0 1.6 1.9e-14 54.0 0.1 2.7 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EGG08350.1 - 1.5e-14 54.4 0.0 2.5e-11 43.9 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EGG08350.1 - 0.00051 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 Abhydrolase_1 PF00561.20 EGG08351.1 - 0.0018 18.0 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG08351.1 - 0.022 14.0 0.0 3.6 6.8 0.0 2.7 2 1 1 3 3 3 0 Serine aminopeptidase, S33 PX PF00787.24 EGG08352.1 - 4.1e-19 68.6 0.0 1.3e-18 67.0 0.0 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EGG08352.1 - 5.8e-07 29.3 2.8 8.1e-05 22.3 0.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like FAM92 PF06730.11 EGG08352.1 - 0.0044 16.5 0.2 0.0091 15.4 0.2 1.5 1 0 0 1 1 1 1 FAM92 protein DUF4110 PF13422.6 EGG08352.1 - 0.09 12.9 1.0 0.27 11.3 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) KDZ PF18758.1 EGG08355.1 - 1.7e-21 76.9 0.6 4.8e-21 75.4 0.6 1.8 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase LRR_4 PF12799.7 EGG08356.1 - 0.035 14.5 5.0 1.6 9.2 1.8 4.6 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF2570 PF10828.8 EGG08357.1 - 0.07 13.0 4.0 1.2 8.9 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Alpha_kinase PF02816.18 EGG08365.1 - 4.5e-10 40.0 0.0 7.4e-10 39.2 0.0 1.3 1 1 0 1 1 1 1 Alpha-kinase family SlyX PF04102.12 EGG08367.1 - 0.023 15.3 3.0 0.1 13.3 0.7 2.3 2 0 0 2 2 2 0 SlyX Spc7 PF08317.11 EGG08372.1 - 1.7e-22 79.7 10.5 2.4e-22 79.2 10.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DIM PF08194.12 EGG08373.1 - 0.38 11.0 0.1 0.38 11.0 0.1 1.8 2 0 0 2 2 2 0 DIM protein Aa_trans PF01490.18 EGG08376.1 - 3.4e-86 289.5 14.3 4e-86 289.3 14.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_C48 PF02902.19 EGG08377.1 - 5.7e-36 124.4 4.9 7.7e-36 124.0 4.9 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LupA PF18242.1 EGG08377.1 - 0.0027 17.4 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Legionella ubiquitin-specific protease A domain Orthopox_C10L PF07020.11 EGG08379.1 - 1.6 9.5 8.3 2.7 8.8 1.0 2.6 2 0 0 2 2 2 0 Orthopoxvirus C10L protein LrgB PF04172.16 EGG08380.1 - 5.8e-30 104.4 3.2 5.8e-30 104.4 3.2 2.2 1 1 1 2 2 2 2 LrgB-like family REV PF00424.18 EGG08380.1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) zf-UBP PF02148.19 EGG08381.1 - 4.8e-21 74.9 3.5 1.6e-20 73.2 3.5 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 EGG08381.1 - 3.1e-17 62.6 0.0 1.6e-16 60.3 0.0 2.0 1 1 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.6 EGG08381.1 - 1.7e-07 31.5 10.4 1.7e-07 31.5 10.4 2.6 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 EGG08381.1 - 6.1e-06 26.4 8.4 2.1e-05 24.7 8.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGG08381.1 - 5.3e-05 23.2 3.4 5.3e-05 23.2 3.4 2.9 1 1 1 2 2 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EGG08381.1 - 0.00027 20.6 6.0 0.00027 20.6 6.0 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGG08381.1 - 0.00042 20.1 9.5 0.00042 20.1 9.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG08381.1 - 0.00056 19.7 8.9 0.00056 19.7 8.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGG08381.1 - 0.00082 19.4 5.3 0.0019 18.2 5.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EGG08381.1 - 0.0012 18.7 16.2 0.0061 16.4 6.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG08381.1 - 0.0028 17.6 8.3 0.0028 17.6 8.3 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 EGG08381.1 - 0.03 14.1 5.5 0.086 12.7 5.5 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Tho2 PF11262.8 EGG08381.1 - 0.26 10.4 7.0 0.47 9.6 7.0 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Prok-RING_4 PF14447.6 EGG08381.1 - 4.9 7.1 23.0 14 5.7 12.2 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 BAR_2 PF10455.9 EGG08383.1 - 0.00079 18.6 1.5 0.00084 18.6 1.5 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Sigma70_r1_2 PF00140.20 EGG08383.1 - 0.23 11.5 2.7 0.38 10.8 2.7 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Macoilin PF09726.9 EGG08383.1 - 0.36 9.3 6.1 0.36 9.4 6.1 1.0 1 0 0 1 1 1 0 Macoilin family DUF1682 PF07946.14 EGG08383.1 - 1.1 8.4 9.5 1.3 8.1 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Mce4_CUP1 PF11887.8 EGG08391.1 - 0.17 11.3 0.0 0.99 8.8 0.0 1.9 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative LRR_8 PF13855.6 EGG08391.1 - 0.84 9.4 8.1 1.2 9.0 0.2 4.1 5 0 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.7 EGG08391.1 - 1 9.9 9.5 6.7 7.3 0.2 5.4 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 EGG08392.1 - 0.041 14.3 1.4 2.3 8.7 0.3 3.0 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) NCKAP5 PF15246.6 EGG08394.1 - 0.0085 15.7 0.4 0.012 15.2 0.4 1.2 1 0 0 1 1 1 1 Nck-associated protein 5, Peripheral clock protein RhoGAP PF00620.27 EGG08395.1 - 2.3e-43 147.6 0.0 4.9e-43 146.6 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EGG08395.1 - 3.7e-10 40.0 1.2 7.5e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BBP1_C PF15272.6 EGG08395.1 - 0.0027 17.5 2.0 0.023 14.5 0.0 2.9 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal GRP PF07172.11 EGG08395.1 - 0.83 10.4 10.4 1.2 9.8 4.0 2.6 2 0 0 2 2 2 0 Glycine rich protein family Toxin_4 PF00706.17 EGG08396.1 - 0.065 13.7 0.4 5.2 7.6 0.0 2.6 2 0 0 2 2 2 0 Anenome neurotoxin UPF0542 PF15086.6 EGG08396.1 - 0.075 13.0 0.5 0.2 11.6 0.5 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 MIP PF00230.20 EGG08397.1 - 4.1e-37 128.1 19.9 5.4e-37 127.7 19.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 EGG08398.1 - 1.4e-38 132.9 16.4 1.8e-38 132.5 16.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Wzy_C PF04932.15 EGG08398.1 - 0.18 11.5 5.5 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 O-Antigen ligase MIP PF00230.20 EGG08399.1 - 1.7e-39 135.8 20.3 2.3e-39 135.4 20.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein Wzy_C PF04932.15 EGG08399.1 - 0.0035 17.0 3.5 0.058 13.0 0.0 2.4 2 0 0 2 2 2 1 O-Antigen ligase LSM PF01423.22 EGG08400.1 - 4.4e-17 61.5 0.3 6.2e-17 61.1 0.3 1.2 1 0 0 1 1 1 1 LSM domain NADH-u_ox-rdase PF10785.9 EGG08401.1 - 3.2e-26 91.8 0.1 5.1e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 EGG08401.1 - 1.7e-17 63.2 0.2 2.6e-17 62.6 0.2 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit ATPase_gene1 PF09527.10 EGG08401.1 - 0.76 10.0 6.0 0.37 11.0 2.5 2.1 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Pil1 PF13805.6 EGG08402.1 - 3.2e-46 158.0 4.4 4.6e-46 157.5 4.4 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 GAS PF13851.6 EGG08402.1 - 0.016 14.6 9.5 0.036 13.4 9.5 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2935 PF11155.8 EGG08402.1 - 0.029 14.7 0.1 0.99 9.7 0.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) AAA_13 PF13166.6 EGG08402.1 - 0.052 12.2 7.4 0.077 11.6 7.4 1.2 1 0 0 1 1 1 0 AAA domain DUF4094 PF13334.6 EGG08402.1 - 0.093 13.2 2.2 0.36 11.3 2.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Spectrin PF00435.21 EGG08402.1 - 0.11 13.0 2.7 0.35 11.4 2.7 1.9 1 0 0 1 1 1 0 Spectrin repeat Bcr-Abl_Oligo PF09036.10 EGG08402.1 - 0.11 12.5 5.7 0.26 11.3 0.6 2.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Cauli_AT PF03233.13 EGG08402.1 - 0.13 12.1 7.7 0.052 13.5 4.6 1.8 2 0 0 2 2 2 0 Aphid transmission protein Seryl_tRNA_N PF02403.22 EGG08402.1 - 0.21 11.9 12.9 0.092 13.0 9.8 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 EGG08402.1 - 1.3 9.4 7.8 4.3 7.8 1.0 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 EGG08402.1 - 2.5 8.6 9.3 1.6 9.2 6.5 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF16 PF01519.16 EGG08402.1 - 2.6 8.6 9.7 0.57 10.7 5.8 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 UPF0449 PF15136.6 EGG08402.1 - 3.2 8.3 10.0 19 5.8 2.4 3.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 AvrM-A PF18241.1 EGG08403.1 - 1.6e-48 164.8 10.5 1.6e-48 164.8 10.5 2.6 2 1 0 2 2 2 1 Flax-rust effector AvrM-A AvrM_N PF18247.1 EGG08403.1 - 7.7e-30 102.6 1.0 7.7e-30 102.6 1.0 2.3 2 0 0 2 2 2 1 Flax-rust effector AvrM N-terminal domain HTH_5 PF01022.20 EGG08405.1 - 0.14 12.0 2.0 3.9 7.4 1.4 2.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Het-C PF07217.11 EGG08407.1 - 3e-192 640.1 0.0 4e-192 639.7 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Mg296 PF09644.10 EGG08408.1 - 0.011 15.8 1.4 0.037 14.2 0.1 2.5 3 0 0 3 3 3 0 Mg296 protein Translin PF01997.16 EGG08409.1 - 1.6e-56 191.6 0.4 1.8e-56 191.4 0.4 1.0 1 0 0 1 1 1 1 Translin family Pyrophosphatase PF00719.19 EGG08409.1 - 0.0099 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase Phg_2220_C PF09524.10 EGG08409.1 - 0.096 12.8 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) OPT PF03169.15 EGG08410.1 - 1e-130 437.3 35.4 1.2e-130 437.1 35.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FMO-like PF00743.19 EGG08412.1 - 6e-12 44.8 0.1 8.5e-07 27.8 0.1 2.4 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGG08412.1 - 3.6e-10 39.6 0.0 7.1e-10 38.6 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG08412.1 - 4.6e-10 39.6 0.1 2.2e-08 34.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGG08412.1 - 1.4e-09 37.6 0.1 5.8e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGG08412.1 - 4.7e-07 29.3 0.5 5.7e-06 25.7 0.1 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EGG08412.1 - 4e-06 26.7 0.1 1.6e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGG08412.1 - 5.6e-06 26.8 3.4 0.0068 16.9 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG08412.1 - 6.4e-05 23.0 0.2 0.00089 19.3 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EGG08412.1 - 0.00012 21.4 0.2 0.087 12.1 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EGG08412.1 - 0.0012 18.2 2.4 0.0026 17.2 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EGG08412.1 - 0.0015 18.6 1.0 0.38 10.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EGG08412.1 - 0.0037 16.4 2.5 0.0056 15.8 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 EGG08412.1 - 0.0066 16.4 2.8 0.0095 15.8 0.2 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EGG08412.1 - 0.016 13.9 4.4 0.028 13.1 0.9 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EGG08412.1 - 0.016 14.4 1.1 0.34 10.1 0.1 2.1 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 EGG08412.1 - 0.017 14.2 2.2 0.098 11.7 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 EGG08412.1 - 0.088 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.23 EGG08412.1 - 0.15 12.0 3.0 0.13 12.2 0.3 2.2 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 EGG08412.1 - 0.6 10.4 1.7 41 4.4 0.3 3.0 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Aldo_ket_red PF00248.21 EGG08417.1 - 3.1e-42 144.8 0.0 3.6e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family APOBEC1 PF18769.1 EGG08417.1 - 0.14 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 APOBEC1 zf-RING_UBOX PF13445.6 EGG08418.1 - 7.9e-10 38.6 0.8 1.9e-09 37.4 0.8 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGG08418.1 - 2.2e-08 34.1 1.5 2.2e-08 34.1 1.5 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGG08418.1 - 8.4e-08 32.4 7.7 2.8e-07 30.8 7.7 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG08418.1 - 1.2e-07 31.4 0.8 1.2e-07 31.4 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG08418.1 - 1.9e-06 27.6 8.2 1.1e-05 25.2 7.4 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG08418.1 - 2.8e-05 24.0 6.0 9.2e-05 22.3 6.0 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGG08418.1 - 3.7e-05 23.5 6.7 5e-05 23.1 2.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EGG08418.1 - 0.003 17.4 1.6 0.0071 16.2 1.6 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 EGG08418.1 - 0.019 14.7 1.7 0.043 13.6 1.7 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 EGG08418.1 - 0.046 14.0 10.8 0.41 11.0 8.4 3.0 2 1 1 3 3 3 0 RING-H2 zinc finger domain HAUS-augmin3 PF14932.6 EGG08418.1 - 0.049 13.2 2.2 0.083 12.5 2.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 CP12 PF02672.15 EGG08418.1 - 0.071 13.9 0.4 0.17 12.7 0.4 1.7 1 0 0 1 1 1 0 CP12 domain Prok-RING_4 PF14447.6 EGG08418.1 - 0.11 12.3 11.4 2.3 8.2 7.3 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGG08418.1 - 0.12 12.5 2.2 0.22 11.6 0.7 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4577 PF15145.6 EGG08418.1 - 0.45 10.6 2.2 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) IBR PF01485.21 EGG08418.1 - 0.57 10.4 9.2 0.54 10.5 2.9 2.7 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 EGG08418.1 - 1.2 9.0 5.9 8.5 6.3 1.2 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF724 PF05266.14 EGG08418.1 - 2.9 7.7 9.3 0.38 10.6 4.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FYVE PF01363.21 EGG08418.1 - 3 8.1 7.0 9.2 6.5 6.7 2.0 1 1 0 1 1 1 0 FYVE zinc finger DUF4164 PF13747.6 EGG08419.1 - 0.018 15.3 1.3 0.018 15.3 1.3 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.19 EGG08419.1 - 0.027 12.4 3.3 0.041 11.8 3.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CheZ PF04344.13 EGG08419.1 - 0.34 10.8 6.9 0.76 9.7 6.9 1.6 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ FapA PF03961.13 EGG08419.1 - 2.5 6.6 6.5 3.9 6.0 6.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Kinesin PF00225.23 EGG08420.1 - 1.1e-107 359.8 0.0 1.3e-107 359.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGG08420.1 - 6.5e-25 87.8 0.0 1.4e-24 86.7 0.0 1.7 1 1 0 1 1 1 1 Microtubule binding Ran_BP1 PF00638.18 EGG08422.1 - 5.5e-48 162.3 0.9 5.5e-48 162.3 0.9 1.8 2 1 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 EGG08422.1 - 2.1e-05 24.4 0.2 8.8e-05 22.4 0.2 1.8 1 1 0 1 1 1 1 WH1 domain Integrase_H2C2 PF17921.1 EGG08423.1 - 0.0057 16.7 0.2 0.016 15.3 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Integrase_H2C2 PF17921.1 EGG08424.1 - 0.0091 16.1 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain TFIIA PF03153.13 EGG08424.1 - 0.64 10.0 26.3 1.1 9.2 26.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RED_N PF07808.13 EGG08424.1 - 1.1 8.7 5.3 2 7.9 5.3 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region Fibrillarin PF01269.17 EGG08425.1 - 6e-105 349.4 0.0 6.9e-105 349.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EGG08425.1 - 1.2e-05 25.1 0.0 1.8e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 EGG08425.1 - 0.0022 17.7 0.0 0.0099 15.5 0.0 2.0 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EGG08425.1 - 0.046 13.5 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EGG08425.1 - 0.089 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Forkhead_N PF08430.12 EGG08426.1 - 0.061 13.9 1.0 0.13 12.9 1.0 1.6 1 0 0 1 1 1 0 Forkhead N-terminal region ER PF01133.17 EGG08426.1 - 0.11 12.5 0.0 9.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Enhancer of rudimentary DUF4171 PF13775.6 EGG08432.1 - 0.067 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) Nop PF01798.18 EGG08433.1 - 5.9e-88 294.2 0.6 9.9e-88 293.5 0.0 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGG08433.1 - 6.8e-22 77.6 0.9 6.8e-22 77.6 0.9 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain SAGA-Tad1 PF12767.7 EGG08433.1 - 2 8.1 7.9 3.6 7.3 7.9 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SRP-alpha_N PF04086.13 EGG08433.1 - 3.2 7.6 18.0 4.3 7.2 18.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Lyase_1 PF00206.20 EGG08435.1 - 5.6e-22 78.5 0.0 8.4e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EGG08435.1 - 3.5e-16 59.5 0.0 1.6e-15 57.3 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Adenylsucc_synt PF00709.21 EGG08436.1 - 1.3e-167 558.0 0.0 1.5e-167 557.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF5427 PF10310.9 EGG08439.1 - 0.75 8.7 7.1 0.21 10.5 3.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5427) zf-CCHC_4 PF14392.6 EGG08440.1 - 0.046 13.4 0.2 0.075 12.8 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EGG08440.1 - 0.2 11.8 2.2 0.31 11.2 2.2 1.3 1 0 0 1 1 1 0 Zinc knuckle NICE-1 PF15845.5 EGG08440.1 - 1.3 9.9 5.4 0.28 12.0 1.1 2.1 3 0 0 3 3 3 0 Cysteine-rich C-terminal 1 family Asp-B-Hydro_N PF05279.11 EGG08441.1 - 5.6 7.0 10.9 6 6.9 10.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ATP19 PF11022.8 EGG08442.1 - 0.19 12.1 1.2 0.39 11.1 1.2 1.8 1 1 0 1 1 1 0 ATP synthase subunit K Med13_C PF06333.12 EGG08442.1 - 3.9 6.7 12.2 4.5 6.5 12.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Dicty_REP PF05086.12 EGG08442.1 - 6.6 4.6 10.5 7 4.5 10.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ApbA_C PF08546.11 EGG08443.1 - 4.6e-29 101.1 0.0 7.5e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EGG08443.1 - 7.4e-10 38.7 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HTH_9 PF08221.11 EGG08446.1 - 2.1e-19 69.4 6.3 4.7e-13 49.0 1.3 3.6 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 EGG08446.1 - 6.3e-14 52.3 4.7 9.8e-12 45.2 0.2 2.7 1 1 1 3 3 3 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 EGG08446.1 - 9.4e-07 28.7 5.4 0.00012 21.9 1.6 4.2 5 0 0 5 5 5 1 TFIIE alpha subunit DNA_ligase_A_N PF04675.14 EGG08446.1 - 0.015 15.7 0.6 0.051 13.9 0.2 2.0 2 0 0 2 2 2 0 DNA ligase N terminus DUF1682 PF07946.14 EGG08450.1 - 0.068 12.4 10.5 0.072 12.3 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) U79_P34 PF03064.16 EGG08450.1 - 0.13 11.6 9.5 0.14 11.5 9.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4746 PF15928.5 EGG08450.1 - 0.21 11.0 6.9 0.22 10.9 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Vfa1 PF08432.10 EGG08450.1 - 1.1 9.5 12.7 1.4 9.3 12.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Fucose_iso_N2 PF07882.12 EGG08450.1 - 1.4 8.5 4.8 2 8.0 4.8 1.2 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Presenilin PF01080.17 EGG08450.1 - 4.6 5.9 6.5 5.7 5.6 6.5 1.1 1 0 0 1 1 1 0 Presenilin IMD PF08397.11 EGG08450.1 - 4.7 6.5 12.6 6.8 6.0 12.6 1.3 1 1 0 1 1 1 0 IRSp53/MIM homology domain Alpha_kinase PF02816.18 EGG08456.1 - 1.8e-29 103.2 0.1 3.3e-29 102.3 0.1 1.5 1 0 0 1 1 1 1 Alpha-kinase family DUF3531 PF12049.8 EGG08456.1 - 0.021 14.8 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3531) Cys_rich_CPCC PF14206.6 EGG08456.1 - 0.27 11.1 4.7 0.66 9.8 4.7 1.6 1 0 0 1 1 1 0 Cysteine-rich CPCC T6SS_TssF PF05947.12 EGG08457.1 - 0.19 10.2 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssF Rogdi_lz PF10259.9 EGG08459.1 - 0.018 14.5 0.2 0.034 13.6 0.2 1.4 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein HD_5 PF13487.6 EGG08461.1 - 0.08 13.2 0.0 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 HD domain LRR_8 PF13855.6 EGG08461.1 - 0.28 11.0 9.4 0.048 13.4 2.2 3.4 4 0 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.7 EGG08462.1 - 0.025 14.5 0.9 0.55 10.2 0.1 2.9 2 0 0 2 2 2 0 F-box-like Chordopox_A13L PF05961.11 EGG08462.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Glyco_hydro_32C PF08244.12 EGG08463.1 - 0.041 13.9 1.5 0.17 11.9 1.1 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal CdhD PF03599.16 EGG08468.1 - 0.044 12.5 0.1 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit CDC45 PF02724.14 EGG08468.1 - 8.6 4.5 9.4 12 4.0 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Tyosinase_C PF18132.1 EGG08472.1 - 0.019 15.7 0.0 0.04 14.6 0.0 1.5 1 0 0 1 1 1 0 Tyosinase C-terminal domain MgtE PF01769.16 EGG08475.1 - 3.4e-37 127.6 23.5 7.9e-20 71.5 6.0 3.2 1 1 2 3 3 3 2 Divalent cation transporter DUF4405 PF14358.6 EGG08475.1 - 4.7 7.8 12.6 13 6.4 0.9 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) DEAD PF00270.29 EGG08478.1 - 5.4e-43 146.8 0.8 9.1e-43 146.0 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG08478.1 - 6.5e-31 107.0 0.1 3.5e-30 104.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG08478.1 - 4.9e-05 23.4 0.0 9.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGG08478.1 - 8.9e-05 22.9 0.1 0.00084 19.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGG08478.1 - 0.015 15.0 0.6 0.032 13.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 EGG08478.1 - 0.016 14.7 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EGG08478.1 - 0.041 13.7 0.1 0.082 12.8 0.1 1.5 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 EGG08478.1 - 0.079 12.9 0.0 0.38 10.7 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain Herpes_U44 PF04533.13 EGG08479.1 - 0.02 14.5 1.9 0.96 9.0 0.4 2.1 1 1 1 2 2 2 0 Herpes virus U44 protein Gp_dh_C PF02800.20 EGG08479.1 - 0.058 13.0 0.1 0.08 12.5 0.1 1.3 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain NRDD PF13597.6 EGG08481.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase tRNA_NucTran2_2 PF13735.6 EGG08482.1 - 0.028 14.4 0.9 0.18 11.8 0.4 2.5 1 1 1 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative C4bp_oligo PF18453.1 EGG08482.1 - 0.031 14.5 0.1 0.08 13.1 0.1 1.7 1 0 0 1 1 1 0 Oligomerization domain of C4b-binding protein alpha Interferon PF00143.19 EGG08482.1 - 0.05 13.8 4.0 0.06 13.5 0.4 2.8 3 0 0 3 3 3 0 Interferon alpha/beta domain Catalase PF00199.19 EGG08485.1 - 3.2e-48 164.8 0.1 3.6e-48 164.6 0.1 1.0 1 0 0 1 1 1 1 Catalase YtzH PF14165.6 EGG08486.1 - 0.028 14.8 1.3 1.2 9.6 0.4 3.0 2 1 0 2 2 2 0 YtzH-like protein TBCC_N PF16752.5 EGG08486.1 - 0.036 14.5 0.6 0.2 12.1 0.0 2.5 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain DUF713 PF05218.14 EGG08486.1 - 1.8 8.2 8.5 0.61 9.8 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF713) HSF_DNA-bind PF00447.17 EGG08487.1 - 1.5e-18 67.2 0.3 1.7e-18 67.0 0.3 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 EGG08487.1 - 0.12 12.9 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Ets-domain HSF_DNA-bind PF00447.17 EGG08488.1 - 5e-06 27.0 0.0 9.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding ATG16 PF08614.11 EGG08488.1 - 0.015 15.5 1.5 0.016 15.5 1.5 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TFIIS_C PF01096.18 EGG08490.1 - 4.5e-16 58.4 7.9 7.8e-16 57.7 0.8 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 EGG08490.1 - 8.2e-06 25.7 4.4 0.032 14.2 0.7 2.4 2 0 0 2 2 2 2 Double zinc ribbon RNA_POL_M_15KD PF02150.16 EGG08490.1 - 8.4e-06 25.6 11.6 0.0003 20.6 2.5 3.1 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit IBR PF01485.21 EGG08490.1 - 0.00062 19.9 3.5 0.19 12.0 0.6 2.3 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain VP_N-CPKC PF11475.8 EGG08490.1 - 0.00097 19.0 1.3 1.1 9.3 0.1 2.7 2 0 0 2 2 2 2 Virion protein N terminal domain zf-ribbon_3 PF13248.6 EGG08490.1 - 0.0031 16.9 10.3 0.3 10.6 0.2 4.1 4 0 0 4 4 4 1 zinc-ribbon domain HypA PF01155.19 EGG08490.1 - 0.0036 17.3 5.9 0.28 11.2 0.2 3.1 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 EGG08490.1 - 0.0094 15.5 8.9 0.84 9.3 0.1 4.2 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 EGG08490.1 - 0.014 15.7 3.6 15 6.0 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon tRNA-synt_1f PF01921.18 EGG08490.1 - 0.016 14.2 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF2387 PF09526.10 EGG08490.1 - 0.026 14.7 2.8 0.35 11.0 0.5 2.5 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-TFIIB PF13453.6 EGG08490.1 - 0.037 13.4 1.8 0.037 13.4 1.8 2.4 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-H2C2_2 PF13465.6 EGG08490.1 - 0.054 14.0 0.4 0.054 14.0 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C4_Topoisom PF01396.19 EGG08490.1 - 0.065 13.0 10.8 4.9 7.0 0.2 3.7 4 0 0 4 4 3 0 Topoisomerase DNA binding C4 zinc finger Zn-ribbon_8 PF09723.10 EGG08490.1 - 0.076 13.2 11.4 1 9.5 0.8 3.6 3 1 0 3 3 3 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 EGG08490.1 - 0.082 12.8 6.9 0.26 11.2 0.8 2.6 2 1 1 3 3 3 0 Domain found in IF2B/IF5 C1_4 PF07975.12 EGG08490.1 - 0.1 12.8 8.2 0.11 12.8 0.9 3.1 3 1 1 4 4 4 0 TFIIH C1-like domain zinc-ribbons_6 PF07191.12 EGG08490.1 - 0.14 12.2 6.6 1.9 8.5 1.6 2.7 2 1 0 2 2 2 0 zinc-ribbons Zn_Tnp_IS91 PF14319.6 EGG08490.1 - 0.17 11.9 6.3 4.7 7.3 0.1 3.2 2 1 1 3 3 3 0 Transposase zinc-binding domain Baculo_LEF5_C PF11792.8 EGG08490.1 - 0.17 11.6 0.0 0.17 11.6 0.0 2.6 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_13 PF09855.9 EGG08490.1 - 0.41 10.9 8.5 12 6.2 0.1 3.7 4 0 0 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-C2HC5 PF06221.13 EGG08490.1 - 0.51 10.4 5.5 1.2 9.2 0.5 3.0 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-AN1 PF01428.16 EGG08490.1 - 0.64 10.2 6.7 6.1 7.1 0.1 3.0 3 1 0 3 3 3 0 AN1-like Zinc finger zinc_ribbon_4 PF13717.6 EGG08490.1 - 0.71 9.8 8.9 1.1 9.3 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-IS66 PF13005.7 EGG08490.1 - 0.82 10.1 8.8 46 4.5 0.2 4.1 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 Auto_anti-p27 PF06677.12 EGG08490.1 - 1.2 9.4 12.1 1.7 8.9 5.5 3.6 3 1 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF3797 PF12677.7 EGG08490.1 - 1.5 8.8 12.8 1.9 8.4 0.0 3.7 2 2 2 4 4 4 0 Domain of unknown function (DUF3797) DUF4379 PF14311.6 EGG08490.1 - 1.8 9.0 4.7 1.4 9.3 1.4 2.4 2 1 1 3 3 2 0 Probable Zinc-ribbon domain Ogr_Delta PF04606.12 EGG08490.1 - 1.9 8.6 8.9 0.26 11.3 2.8 2.6 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger TF_Zn_Ribbon PF08271.12 EGG08490.1 - 2.8 7.5 15.1 5.9 6.5 4.5 3.5 2 2 0 2 2 2 0 TFIIB zinc-binding Nudix_N_2 PF14803.6 EGG08490.1 - 3 7.8 11.9 17 5.4 0.2 4.1 2 2 2 4 4 4 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 EGG08490.1 - 3.2 7.6 17.5 0.77 9.6 0.8 3.9 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 EGG08490.1 - 3.5 8.5 9.6 9.4e+02 0.7 9.6 3.2 1 1 0 1 1 1 0 zinc-ribbon family A2L_zn_ribbon PF08792.10 EGG08490.1 - 3.6 7.4 14.1 28 4.6 0.1 4.2 4 0 0 4 4 4 0 A2L zinc ribbon domain DNA_RNApol_7kD PF03604.13 EGG08490.1 - 6.3 6.6 7.5 15 5.4 0.2 3.0 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_1 PF14446.6 EGG08490.1 - 6.3 6.8 9.5 42 4.2 0.1 3.5 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 Lar_restr_allev PF14354.6 EGG08490.1 - 6.4 7.2 12.0 31 5.1 0.6 3.9 2 2 0 2 2 2 0 Restriction alleviation protein Lar APG6_N PF17675.1 EGG08492.1 - 0.0033 18.0 10.7 0.0033 18.0 10.7 2.0 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF1515 PF07439.11 EGG08492.1 - 0.0077 16.2 0.7 0.067 13.2 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1515) ABC_tran_CTD PF16326.5 EGG08492.1 - 0.028 14.7 12.9 0.051 13.8 0.0 4.4 3 1 1 4 4 4 0 ABC transporter C-terminal domain Osmo_CC PF08946.10 EGG08492.1 - 0.91 9.8 5.1 7.6 6.9 1.0 3.7 4 0 0 4 4 4 0 Osmosensory transporter coiled coil Zn_clus PF00172.18 EGG08494.1 - 0.57 10.3 7.1 3.8 7.7 2.0 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HGD-D PF06050.13 EGG08496.1 - 0.01 15.6 0.2 0.085 12.6 0.0 2.4 3 0 0 3 3 3 0 2-hydroxyglutaryl-CoA dehydratase, D-component NPV_P10 PF05531.12 EGG08496.1 - 0.11 13.0 12.9 2.2 8.8 0.1 4.4 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4988 PF16378.5 EGG08496.1 - 0.2 11.3 2.1 14 5.3 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function LPP PF04728.13 EGG08496.1 - 0.31 11.4 3.3 0.95 9.9 0.7 3.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Zn_clus PF00172.18 EGG08497.1 - 1.1 9.4 6.6 20 5.4 3.1 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain E7 PF00527.18 EGG08497.1 - 1.6 8.9 3.9 3 8.1 0.5 2.4 2 0 0 2 2 2 0 E7 protein, Early protein DnaJ PF00226.31 EGG08498.1 - 1.4e-08 34.7 0.0 3.9e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.6 EGG08498.1 - 0.00031 21.0 0.1 0.87 9.9 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG08498.1 - 0.00055 19.8 0.2 1.3 9.3 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG08498.1 - 0.003 18.0 0.3 0.028 14.9 0.3 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG08498.1 - 0.02 15.0 0.3 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGG08498.1 - 0.033 14.4 0.9 15 6.1 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG08498.1 - 0.039 14.6 0.1 19 6.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DAO PF01266.24 EGG08500.1 - 1.5e-47 162.9 0.0 1.8e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 EGG08500.1 - 0.00023 19.9 0.0 0.0095 14.5 0.0 2.4 3 0 0 3 3 3 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 EGG08500.1 - 0.00026 21.1 0.0 0.00083 19.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG08500.1 - 0.015 14.5 0.0 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG08500.1 - 0.14 12.8 0.0 0.8 10.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MIP PF00230.20 EGG08501.1 - 3e-23 82.7 7.8 9.7e-23 81.1 7.8 1.7 1 1 0 1 1 1 1 Major intrinsic protein MMR_HSR1 PF01926.23 EGG08505.1 - 8.6e-12 45.1 0.0 2.6e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG08505.1 - 7.6e-06 25.9 0.2 0.0019 18.1 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGG08505.1 - 0.0024 17.4 0.1 0.0089 15.6 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGG08505.1 - 0.0074 16.4 0.7 0.19 11.8 0.0 3.0 2 1 1 3 3 3 1 Dynamin family AAA_18 PF13238.6 EGG08505.1 - 0.01 16.4 0.8 0.042 14.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Prominin PF05478.11 EGG08505.1 - 0.14 10.1 0.3 0.23 9.4 0.3 1.2 1 0 0 1 1 1 0 Prominin Syntaxin_2 PF14523.6 EGG08506.1 - 0.4 11.1 1.3 0.45 10.9 0.1 1.6 2 0 0 2 2 2 0 Syntaxin-like protein F-box-like PF12937.7 EGG08507.1 - 0.00017 21.4 0.0 0.00044 20.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG08507.1 - 0.012 15.5 0.2 1.3 9.0 0.0 2.8 2 0 0 2 2 2 0 F-box domain Cellulase PF00150.18 EGG08510.1 - 1.5e-37 129.6 0.0 1.8e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Septum_form PF13845.6 EGG08510.1 - 0.096 12.2 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Septum formation DPBB_1 PF03330.18 EGG08511.1 - 8.5e-08 32.4 0.1 9.3e-08 32.2 0.1 1.3 1 1 0 1 1 1 1 Lytic transglycolase DUF2461 PF09365.10 EGG08512.1 - 3.8e-66 223.0 0.0 6.2e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) SOAR PF16533.5 EGG08512.1 - 0.062 13.3 1.9 0.11 12.4 0.5 2.0 2 0 0 2 2 2 0 STIM1 Orai1-activating region Tubulin PF00091.25 EGG08513.1 - 2.4e-68 230.2 0.0 4.6e-68 229.3 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGG08513.1 - 9.6e-42 142.1 0.1 1.5e-41 141.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGG08513.1 - 2.5e-05 24.6 0.4 6.7e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGG08513.1 - 0.0055 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGG08513.1 - 0.0074 15.5 0.0 0.029 13.6 0.0 1.8 2 0 0 2 2 2 1 Tubulin like SDA1 PF05285.12 EGG08514.1 - 0.77 9.1 5.6 0.34 10.3 3.3 1.5 2 0 0 2 2 2 0 SDA1 Curto_V2 PF07325.11 EGG08514.1 - 2.6 7.9 5.2 4.8 7.1 5.2 1.4 1 0 0 1 1 1 0 Curtovirus V2 protein NAM-associated PF14303.6 EGG08516.1 - 0.026 15.2 0.6 0.026 15.2 0.6 2.7 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain GAS PF13851.6 EGG08517.1 - 0.067 12.5 1.1 0.099 12.0 0.1 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sen15 PF09631.10 EGG08519.1 - 1.9e-23 82.7 0.1 2.4e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 Sen15 protein DNA_ligase_IV PF11411.8 EGG08519.1 - 0.13 12.5 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 DNA ligase IV Pkinase PF00069.25 EGG08521.1 - 1.7e-65 221.1 0.2 8.9e-60 202.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG08521.1 - 3.8e-35 121.4 0.2 2e-32 112.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 EGG08521.1 - 1.3e-17 63.3 0.3 2.5e-17 62.4 0.3 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 EGG08521.1 - 8.9e-05 21.6 0.0 0.00017 20.6 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGG08521.1 - 0.00022 20.6 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG08521.1 - 0.00023 20.6 0.0 0.00042 19.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG08521.1 - 0.00057 19.9 0.0 0.0046 16.9 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family WaaY PF06176.11 EGG08521.1 - 0.024 14.2 0.2 0.048 13.3 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 EGG08521.1 - 0.2 11.2 0.1 0.51 9.9 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase TF_Zn_Ribbon PF08271.12 EGG08522.1 - 0.39 10.3 0.1 0.39 10.3 0.1 2.3 3 0 0 3 3 3 0 TFIIB zinc-binding DUF1057 PF06342.12 EGG08523.1 - 0.12 11.4 0.0 0.39 9.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Chordopox_A13L PF05961.11 EGG08524.1 - 0.0022 18.2 0.1 0.0022 18.2 0.1 2.4 3 0 0 3 3 3 1 Chordopoxvirus A13L protein BRI3BP PF14965.6 EGG08524.1 - 0.042 13.4 2.0 0.061 12.8 2.0 1.1 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Sigma_reg_N PF13800.6 EGG08524.1 - 0.061 13.6 0.2 0.061 13.6 0.2 2.3 2 1 0 2 2 2 0 Sigma factor regulator N-terminal DUF4597 PF15366.6 EGG08524.1 - 0.079 12.7 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Pilin_N PF07790.11 EGG08524.1 - 0.091 13.7 0.7 0.4 11.6 0.1 2.1 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal RRXRR PF14239.6 EGG08524.1 - 0.16 11.8 3.3 0.21 11.4 3.3 1.1 1 0 0 1 1 1 0 RRXRR protein DUF3098 PF11297.8 EGG08524.1 - 0.18 11.4 0.3 0.18 11.4 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) DUF2809 PF10990.8 EGG08524.1 - 0.46 11.2 5.3 1.8 9.3 5.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2809) DUF4131 PF13567.6 EGG08524.1 - 7.6 6.2 6.3 34 4.0 6.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Glyco_hydro_61 PF03443.14 EGG08525.1 - 1.3e-26 93.8 1.9 1.8e-26 93.4 0.0 2.1 2 2 0 2 2 2 1 Glycosyl hydrolase family 61 CFEM PF05730.11 EGG08525.1 - 8.4e-05 22.6 10.6 8.4e-05 22.6 10.6 2.6 2 0 0 2 2 2 1 CFEM domain DM PF00751.18 EGG08525.1 - 0.72 9.8 10.8 1.3 9.0 0.2 2.5 2 0 0 2 2 2 0 DM DNA binding domain RIO1 PF01163.22 EGG08527.1 - 9.7e-46 155.7 1.2 1e-45 155.7 0.1 1.5 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 EGG08527.1 - 7.7e-34 115.8 0.0 2.1e-33 114.4 0.0 1.7 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 EGG08527.1 - 9.3e-10 38.8 1.6 4.2e-06 26.9 0.2 3.3 1 1 2 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EGG08527.1 - 1.9e-08 33.9 0.0 5.6e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGG08527.1 - 0.0042 15.9 0.0 0.0063 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase TrmB PF01978.19 EGG08527.1 - 0.021 14.7 0.4 0.074 12.9 0.1 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 EGG08527.1 - 0.073 13.1 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 EGG08527.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 MarR family Polysacc_synt_4 PF04669.13 EGG08529.1 - 7e-19 68.1 0.9 8.4e-17 61.3 0.9 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis CSN8_PSD8_EIF3K PF10075.9 EGG08530.1 - 4.3e-16 59.2 0.0 6.6e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family adh_short_C2 PF13561.6 EGG08531.1 - 6.2e-62 209.2 0.0 7.8e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG08531.1 - 1.3e-50 171.6 0.0 1.7e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG08531.1 - 8.1e-13 48.7 0.0 1.5e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG08531.1 - 6.3e-05 22.6 0.0 9.6e-05 21.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG08531.1 - 0.00033 19.8 0.1 0.00042 19.4 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGG08531.1 - 0.15 11.4 0.1 1.1 8.6 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ThiF PF00899.21 EGG08531.1 - 3.3 7.0 4.8 0.92 8.8 1.3 1.8 2 1 0 2 2 2 0 ThiF family Abhydrolase_2 PF02230.16 EGG08533.1 - 4.8e-08 33.1 0.0 7.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2417 PF10329.9 EGG08533.1 - 0.0057 16.1 0.4 0.0088 15.5 0.4 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) RRM_1 PF00076.22 EGG08534.1 - 1.5e-38 130.5 0.1 1.4e-23 82.5 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EGG08534.1 - 9.2e-11 42.7 3.6 9.2e-09 36.3 0.2 3.9 3 1 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 EGG08534.1 - 6.3e-05 23.0 0.0 0.00035 20.6 0.0 2.3 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 EGG08534.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG08534.1 - 0.041 13.7 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_9 PF18444.1 EGG08534.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif Malectin PF11721.8 EGG08535.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Malectin domain GshA PF08886.11 EGG08536.1 - 0.075 11.6 0.0 0.075 11.6 0.0 1.0 1 0 0 1 1 1 0 Glutamate-cysteine ligase CDP-OH_P_transf PF01066.21 EGG08537.1 - 5.4e-06 27.1 0.0 7.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Importin_rep_3 PF18806.1 EGG08537.1 - 0.097 12.7 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Importin 13 repeat Ammonium_transp PF00909.21 EGG08538.1 - 1.9e-116 389.0 31.8 2.2e-116 388.8 31.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 EGG08538.1 - 1.1 9.3 7.0 0.34 10.9 1.1 2.7 2 0 0 2 2 2 0 Bacteriophage P21 holin S Glug PF07581.12 EGG08538.1 - 2.3 8.8 6.5 0.95 10.0 0.3 3.3 3 0 0 3 3 3 0 The GLUG motif DUF1754 PF08555.10 EGG08539.1 - 3.6e-12 46.9 4.0 3.6e-12 46.9 4.0 1.7 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) FUR PF01475.19 EGG08539.1 - 0.038 14.2 0.1 0.057 13.6 0.1 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family Ashwin PF15323.6 EGG08539.1 - 0.039 14.0 9.2 0.047 13.7 9.2 1.1 1 0 0 1 1 1 0 Developmental protein ATP-synt_G PF04718.15 EGG08539.1 - 0.12 13.2 0.8 0.22 12.4 0.8 1.6 1 1 0 1 1 1 0 Mitochondrial ATP synthase g subunit DUF4805 PF16063.5 EGG08539.1 - 0.18 11.1 6.7 0.22 10.8 6.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4805) DUF334 PF03904.13 EGG08539.1 - 0.39 10.2 6.5 0.49 9.9 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) NinG PF05766.12 EGG08539.1 - 5.5 6.9 8.3 1.7 8.5 4.2 1.8 1 1 1 2 2 2 0 Bacteriophage Lambda NinG protein WGG PF10273.9 EGG08541.1 - 3.2e-13 50.1 0.1 6.2e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Tudor_RapA PF18337.1 EGG08541.1 - 0.048 13.8 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 RapA N-terminal Tudor like domain RRP7 PF12923.7 EGG08541.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DnaJ-X PF14308.6 EGG08542.1 - 2.1e-40 138.4 2.9 2.2e-40 138.3 0.1 2.0 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGG08542.1 - 2.6e-25 88.3 0.2 6.4e-25 87.1 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4674 PF15719.5 EGG08542.1 - 0.039 14.0 0.2 0.039 14.0 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4674) zinc_ribbon_5 PF13719.6 EGG08542.1 - 0.057 13.2 0.6 5.1 6.9 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 EGG08542.1 - 0.15 12.0 1.3 15 5.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TMEM247 PF15444.6 EGG08542.1 - 0.31 11.1 2.1 0.69 9.9 2.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 247 DUF3456 PF11938.8 EGG08542.1 - 9 6.8 6.9 0.86 10.1 0.1 2.4 2 1 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP tRNA-synt_1b PF00579.25 EGG08543.1 - 1.8e-54 185.1 0.0 2.6e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TPM_phosphatase PF04536.14 EGG08544.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 TPM domain Lipase_GDSL PF00657.22 EGG08545.1 - 4.3e-06 26.9 0.2 5.8e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EGG08545.1 - 0.0055 17.1 2.1 0.015 15.7 2.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF2833 PF11090.8 EGG08547.1 - 0.016 15.6 0.4 0.04 14.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) CDC45 PF02724.14 EGG08547.1 - 4 5.6 12.6 5.8 5.1 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EGG08547.1 - 7.9 5.1 7.4 11 4.6 7.4 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 EGG08547.1 - 9.9 4.8 9.6 16 4.2 9.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tub_N PF16322.5 EGG08548.1 - 1.3 9.3 13.6 4.6 7.6 8.5 1.9 1 1 1 2 2 2 0 Tubby N-terminal Ion_trans_2 PF07885.16 EGG08551.1 - 5.3e-31 106.4 28.3 3.4e-15 55.8 8.4 2.7 2 0 0 2 2 2 2 Ion channel 7TMR-DISM_7TM PF07695.11 EGG08551.1 - 0.0014 18.6 2.0 0.0014 18.6 2.0 3.1 2 1 1 3 3 3 1 7TM diverse intracellular signalling Lig_chan PF00060.26 EGG08551.1 - 0.11 12.3 11.1 1.3 8.8 0.6 3.7 3 1 0 3 3 3 0 Ligand-gated ion channel CrgA PF06781.12 EGG08551.1 - 0.97 9.5 3.0 4.1 7.5 0.0 3.4 4 0 0 4 4 4 0 Cell division protein CrgA Borrelia_orfA PF02414.15 EGG08552.1 - 0.075 12.7 1.4 0.35 10.5 0.3 2.1 2 0 0 2 2 2 0 Borrelia ORF-A YebO PF13974.6 EGG08552.1 - 8.5 6.5 6.9 2.4 8.3 2.9 2.1 2 0 0 2 2 2 0 YebO-like protein zf-CSL PF05207.13 EGG08553.1 - 1.9e-20 72.3 0.3 3e-20 71.7 0.3 1.3 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.15 EGG08553.1 - 0.0042 17.2 0.1 0.0083 16.3 0.1 1.5 1 0 0 1 1 1 1 C4-type zinc ribbon domain Zn-ribbon_8 PF09723.10 EGG08553.1 - 0.0056 16.8 0.4 0.0098 16.0 0.4 1.5 1 0 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_4 PF13717.6 EGG08553.1 - 0.022 14.7 0.5 0.036 14.0 0.5 1.3 1 0 0 1 1 1 0 zinc-ribbon domain UPF0172 PF03665.13 EGG08555.1 - 1.8e-41 142.3 0.0 2.2e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 EGG08555.1 - 0.019 14.9 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Synaptobrevin PF00957.21 EGG08556.1 - 0.047 13.5 0.3 0.071 12.9 0.3 1.3 1 0 0 1 1 1 0 Synaptobrevin Thiolase_N PF00108.23 EGG08559.1 - 8.8e-63 212.1 0.2 1.2e-62 211.6 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGG08559.1 - 1.7e-46 156.9 0.3 3.7e-46 155.8 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 EGG08559.1 - 0.00082 19.5 0.1 0.0031 17.6 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EGG08559.1 - 0.039 13.8 0.1 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EGG08559.1 - 0.16 11.5 2.4 0.22 11.1 0.7 2.1 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Aim21 PF11489.8 EGG08560.1 - 0.39 9.6 6.2 0.7 8.7 6.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 Cellulase PF00150.18 EGG08561.1 - 2.2e-09 37.2 0.0 1.1e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NIF PF03031.18 EGG08562.1 - 1.3e-53 181.0 0.0 1.7e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_like PF13242.6 EGG08563.1 - 0.0078 16.2 0.0 0.0089 16.1 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like CH PF00307.31 EGG08564.1 - 1.5e-75 250.4 0.1 6.3e-18 65.0 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EGG08564.1 - 2.1e-06 28.1 0.1 3.5e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGG08564.1 - 3.7e-06 26.1 0.2 0.027 14.0 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGG08564.1 - 0.00023 20.8 0.1 0.043 13.7 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain CAMSAP_CH PF11971.8 EGG08564.1 - 0.00074 19.3 0.0 1.2 9.0 0.0 3.4 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_5 PF13202.6 EGG08564.1 - 0.0059 16.0 1.1 0.16 11.5 0.0 3.4 3 0 0 3 3 3 1 EF hand HMG_CoA_synt_N PF01154.17 EGG08564.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal adh_short PF00106.25 EGG08566.1 - 3.4e-83 277.9 14.3 1.9e-42 144.9 2.2 2.5 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG08566.1 - 3.4e-68 229.7 12.9 8.1e-36 123.7 1.9 3.1 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG08566.1 - 1.1e-31 110.2 6.8 1.6e-17 64.0 0.8 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.19 EGG08566.1 - 1.1e-26 92.9 0.0 2.2e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain 3HCDH_N PF02737.18 EGG08566.1 - 6.8e-05 22.8 6.1 0.071 13.0 0.7 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EGG08566.1 - 0.00051 19.4 1.0 0.25 10.7 0.2 3.3 3 0 0 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PALP PF00291.25 EGG08566.1 - 0.0045 16.4 1.7 0.021 14.3 0.1 2.3 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 EGG08566.1 - 0.12 12.3 3.2 0.63 10.0 0.4 2.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 EGG08566.1 - 0.69 9.5 2.7 25 4.4 0.1 2.9 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglL_A PF15864.5 EGG08566.1 - 2.3 8.0 8.2 10 6.0 1.0 2.7 2 0 0 2 2 2 0 Protein glycosylation ligase adh_short PF00106.25 EGG08568.1 - 6.3e-81 270.5 14.5 1e-40 139.3 2.7 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG08568.1 - 6.5e-67 225.5 13.8 7.2e-35 120.6 2.6 3.0 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG08568.1 - 2.1e-30 106.0 7.3 1.1e-17 64.5 1.0 2.5 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.19 EGG08568.1 - 1.5e-27 95.6 0.0 3.3e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain 3HCDH_N PF02737.18 EGG08568.1 - 0.0013 18.6 7.1 0.17 11.8 0.5 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EGG08568.1 - 0.022 14.1 1.4 1.9 7.7 0.1 2.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 EGG08568.1 - 0.14 12.2 1.7 2.6 8.1 0.2 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1912 PF08930.10 EGG08568.1 - 0.22 11.7 0.4 32 4.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) ADH_zinc_N PF00107.26 EGG08568.1 - 0.22 11.5 4.5 0.83 9.6 1.0 2.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PglL_A PF15864.5 EGG08568.1 - 2.4 8.0 8.2 10 6.0 1.0 2.6 2 0 0 2 2 2 0 Protein glycosylation ligase PGA2 PF07543.12 EGG08571.1 - 0.13 12.2 0.8 0.25 11.3 0.8 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Colicin PF01024.19 EGG08572.1 - 0.17 11.8 2.1 0.45 10.4 2.1 1.7 1 1 0 1 1 1 0 Colicin pore forming domain PIP5K PF01504.18 EGG08575.1 - 1.5e-34 119.5 8.1 5.6e-27 94.6 0.0 2.9 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EGG08575.1 - 5.6e-26 91.2 0.1 8.6e-26 90.6 0.1 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EGG08575.1 - 1.8e-17 63.2 7.4 3.6e-17 62.3 7.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EGG08575.1 - 2.1 8.6 4.3 4.9 7.4 4.3 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 EGG08575.1 - 3.1 8.2 8.7 2.8 8.3 6.2 2.3 2 0 0 2 2 2 0 C1 domain HEPN_Swt1 PF18731.1 EGG08576.1 - 0.046 14.1 0.0 0.046 14.1 0.0 3.0 4 0 0 4 4 4 0 Swt1-like HEPN Alanine_zipper PF11839.8 EGG08580.1 - 0.0065 16.8 0.7 0.015 15.7 0.7 1.6 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein DUF4451 PF14616.6 EGG08581.1 - 2e-30 105.5 0.2 5.2e-30 104.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) PRP3 PF08572.10 EGG08582.1 - 1.9e-70 237.1 5.1 1.9e-70 237.1 5.1 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EGG08582.1 - 7.9e-44 149.3 0.0 7.9e-44 149.3 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) BLUF PF04940.12 EGG08582.1 - 0.021 15.0 0.1 0.095 12.8 0.0 2.1 2 0 0 2 2 2 0 Sensors of blue-light using FAD Ribosomal_L6 PF00347.23 EGG08584.1 - 1.9e-25 89.3 5.1 2.2e-12 47.5 2.6 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Rad60-SLD PF11976.8 EGG08585.1 - 9.1e-20 70.3 0.1 1.1e-19 70.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGG08585.1 - 2.8e-10 39.8 0.0 3.7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Raftlin PF15250.6 EGG08586.1 - 0.018 13.8 2.3 0.023 13.5 2.3 1.1 1 0 0 1 1 1 0 Raftlin FAR1 PF03101.15 EGG08587.1 - 0.0017 19.0 0.4 0.15 12.8 0.2 2.7 2 1 0 2 2 2 2 FAR1 DNA-binding domain Egh16-like PF11327.8 EGG08588.1 - 7.4e-46 156.9 3.9 1e-45 156.4 3.9 1.2 1 0 0 1 1 1 1 Egh16-like virulence factor DUF3716 PF12511.8 EGG08588.1 - 0.27 11.3 2.3 0.51 10.4 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Autophagy_N PF03986.13 EGG08589.1 - 9.6e-43 145.4 0.6 1.9e-42 144.4 0.0 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EGG08589.1 - 9.8e-18 64.5 0.6 1.8e-17 63.7 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EGG08589.1 - 7.9e-15 54.1 1.7 1.5e-14 53.2 1.7 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Chordopox_A33R PF05966.12 EGG08592.1 - 0.013 14.7 0.1 0.031 13.6 0.1 1.6 1 0 0 1 1 1 0 Chordopoxvirus A33R protein NAP PF00956.18 EGG08594.1 - 4.2e-19 68.8 4.6 1.8e-18 66.7 4.6 1.9 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) Carn_acyltransf PF00755.20 EGG08598.1 - 1.2e-188 628.5 0.0 1.3e-188 628.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RNA_pol_L_2 PF13656.6 EGG08598.1 - 0.012 15.4 0.0 8.4 6.3 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain ICE2 PF08426.10 EGG08600.1 - 3.9e-73 246.9 27.1 1.2e-72 245.2 27.1 1.6 1 1 0 1 1 1 1 ICE2 TRAPPC9-Trs120 PF08626.11 EGG08601.1 - 2.7e-105 353.0 19.7 1.1e-102 344.3 19.7 2.5 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Transglut_C PF00927.22 EGG08601.1 - 0.00033 20.8 0.0 0.0088 16.2 0.0 2.7 2 0 0 2 2 2 1 Transglutaminase family, C-terminal ig like domain AAT PF03417.16 EGG08601.1 - 0.044 13.5 0.3 0.097 12.3 0.3 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TPR_11 PF13414.6 EGG08601.1 - 0.073 12.8 0.0 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 EGG08601.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGG08601.1 - 0.18 11.7 0.0 0.6 10.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PIN_4 PF13638.6 EGG08603.1 - 7.1e-07 29.6 0.0 2.3e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 PIN domain GTP_EFTU PF00009.27 EGG08604.1 - 4.5e-59 199.3 0.1 8.8e-59 198.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGG08604.1 - 1.1e-34 118.8 0.1 3.1e-34 117.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EGG08604.1 - 3.1e-31 107.3 0.2 1.1e-30 105.5 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 EGG08604.1 - 7.4e-24 83.6 0.1 2e-23 82.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGG08604.1 - 2.4e-14 53.5 0.1 7e-14 52.0 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGG08604.1 - 1.3e-06 28.3 0.0 3.5e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Pet127 PF08634.10 EGG08604.1 - 0.063 12.7 3.1 0.12 11.8 3.1 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet127 HSA PF07529.13 EGG08606.1 - 4.7e-10 39.6 4.2 4.7e-10 39.6 4.2 4.3 3 1 1 4 4 2 1 HSA Myb_DNA-bind_6 PF13921.6 EGG08606.1 - 4.9e-05 23.5 0.0 0.00018 21.7 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGG08606.1 - 0.00052 20.1 0.1 0.004 17.3 0.0 2.4 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 SART-1 PF03343.13 EGG08606.1 - 0.001 17.7 11.2 0.001 17.7 11.2 2.4 2 0 0 2 2 2 1 SART-1 family FapA PF03961.13 EGG08606.1 - 0.087 11.4 3.1 0.19 10.3 3.1 1.6 1 0 0 1 1 1 0 Flagellar Assembly Protein A Lycopene_cycl PF05834.12 EGG08606.1 - 0.11 11.6 0.4 0.98 8.4 0.6 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein LMBR1 PF04791.16 EGG08606.1 - 1.4 7.8 6.0 2.4 7.0 6.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein eIF-3_zeta PF05091.12 EGG08606.1 - 1.7 7.6 23.5 3.3 6.6 23.5 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Serinc PF03348.15 EGG08606.1 - 1.8 7.4 8.1 2.9 6.7 8.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.6 EGG08606.1 - 5.2 5.4 7.2 9.1 4.6 7.2 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SpoIIP PF07454.11 EGG08606.1 - 5.7 6.3 22.9 17 4.8 22.9 1.7 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4471 PF14740.6 EGG08606.1 - 6.4 5.9 19.9 1.2 8.2 15.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) EIIBC-GUT_N PF03612.14 EGG08606.1 - 8.2 6.1 14.5 24 4.6 14.5 1.8 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pal1 PF08316.11 EGG08606.1 - 9.4 7.0 11.9 45 4.8 11.9 2.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Med31 PF05669.12 EGG08607.1 - 1.8e-29 101.5 2.0 2.2e-29 101.3 2.0 1.1 1 0 0 1 1 1 1 SOH1 DNA_binding_2 PF13724.6 EGG08608.1 - 0.52 10.7 0.1 0.52 10.7 0.1 3.0 2 1 0 2 2 2 0 DNA-binding domain DUF4698 PF15769.5 EGG08608.1 - 0.7 8.9 6.3 0.75 8.8 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Macoilin PF09726.9 EGG08608.1 - 2 6.9 10.3 2.1 6.8 10.3 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 EGG08608.1 - 5.5 5.1 14.4 6.2 5.0 14.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DAHP_synth_1 PF00793.20 EGG08609.1 - 1.6e-100 335.6 0.0 2e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family OSK PF17182.4 EGG08609.1 - 0.19 10.9 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 OSK domain MPC PF03650.13 EGG08610.1 - 1.2e-30 105.8 0.3 1.5e-30 105.6 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MPC PF03650.13 EGG08611.1 - 1.4e-32 112.1 0.2 1.5e-32 112.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers CxC5 PF18718.1 EGG08612.1 - 5.2e-31 107.1 5.3 9.9e-31 106.3 5.3 1.5 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG08612.1 - 5.9e-22 77.7 4.9 1.5e-21 76.4 4.9 1.7 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases zf_C2HC_14 PF18574.1 EGG08612.1 - 0.058 13.2 0.3 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 C2HC Zing finger domain DUF5452 PF17533.2 EGG08614.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5452) Lipase_GDSL_2 PF13472.6 EGG08619.1 - 0.00071 20.0 0.0 0.0011 19.4 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Scm3 PF10384.9 EGG08620.1 - 9.4e-07 28.5 0.9 2.6e-06 27.1 0.9 1.8 1 0 0 1 1 1 1 Centromere protein Scm3 Caldesmon PF02029.15 EGG08620.1 - 0.019 13.8 4.9 0.035 12.9 4.9 1.3 1 0 0 1 1 1 0 Caldesmon Rax2 PF12768.7 EGG08622.1 - 0.025 14.1 0.5 0.035 13.6 0.5 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity FoP_duplication PF13865.6 EGG08622.1 - 5.5 7.6 8.1 9.5 6.9 8.1 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 CxC5 PF18718.1 EGG08623.1 - 6e-24 84.4 1.0 1.3e-23 83.3 1.0 1.5 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG08623.1 - 2.9e-05 24.3 0.3 9.6e-05 22.6 0.3 1.9 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases Alpha_kinase PF02816.18 EGG08624.1 - 5.6e-09 36.4 1.2 1.5e-08 35.0 0.3 1.9 2 0 0 2 2 2 1 Alpha-kinase family Zip PF02535.22 EGG08624.1 - 0.15 11.3 1.6 0.16 11.2 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter zf-CCHC PF00098.23 EGG08625.1 - 0.00045 20.2 0.3 0.00084 19.3 0.3 1.4 1 0 0 1 1 1 1 Zinc knuckle Alpha_kinase PF02816.18 EGG08626.1 - 2.8e-05 24.3 0.0 4.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family CIA30 PF08547.12 EGG08627.1 - 5.9e-31 107.6 0.0 7.5e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) ADC PF06314.11 EGG08628.1 - 6.9e-07 29.1 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) PhnI PF05861.12 EGG08630.1 - 0.005 15.7 0.1 0.0063 15.4 0.1 1.1 1 0 0 1 1 1 1 Bacterial phosphonate metabolism protein (PhnI) KptA_kDCL PF18176.1 EGG08630.1 - 0.025 14.4 4.6 5.9 6.7 4.5 2.3 1 1 0 1 1 1 0 KptA in kinetoplastid DICER domain CCSAP PF15748.5 EGG08630.1 - 0.28 11.3 9.7 0.38 10.9 9.7 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Kinesin PF00225.23 EGG08631.1 - 1.5e-104 349.6 0.9 8.2e-104 347.1 0.0 2.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGG08631.1 - 2.5e-24 85.9 0.0 8.1e-17 61.5 0.0 3.6 3 0 0 3 3 3 2 Microtubule binding DUF1640 PF07798.11 EGG08631.1 - 0.0019 18.3 7.1 0.0019 18.3 7.1 4.8 1 1 2 4 4 4 1 Protein of unknown function (DUF1640) Qua1 PF16274.5 EGG08631.1 - 0.17 11.7 2.9 0.99 9.3 2.9 2.3 1 0 0 1 1 1 0 Qua1 domain Baculo_PEP_C PF04513.12 EGG08631.1 - 1.4 8.9 26.6 1.1 9.3 0.1 6.0 5 2 2 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus LtuB PF17455.2 EGG08631.1 - 4.8 7.9 6.7 0.83 10.3 0.6 2.9 3 0 0 3 3 3 0 Late transcription unit B Prenyltransf PF01255.19 EGG08632.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF5099 PF17025.5 EGG08632.1 - 0.004 17.6 0.0 0.017 15.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5099) zf-ZPR1 PF03367.13 EGG08633.1 - 2.1e-109 362.5 0.8 5.4e-56 188.9 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 EGG08633.1 - 0.0004 20.4 1.0 1 9.4 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EGG08633.1 - 0.0059 16.6 5.2 0.062 13.3 0.3 2.8 2 1 0 2 2 2 1 Double zinc ribbon Zn-ribbon_8 PF09723.10 EGG08633.1 - 0.045 13.9 3.4 5.4 7.2 0.4 3.6 3 1 0 3 3 3 0 Zinc ribbon domain DiS_P_DiS PF06750.13 EGG08633.1 - 0.078 13.1 0.8 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zinc-ribbons_6 PF07191.12 EGG08633.1 - 0.082 12.9 1.7 3.4 7.7 0.0 2.6 2 1 0 2 2 2 0 zinc-ribbons DUF3716 PF12511.8 EGG08633.1 - 0.42 10.7 0.1 0.42 10.7 0.1 2.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3716) zinc_ribbon_2 PF13240.6 EGG08633.1 - 6.4 6.6 15.5 7.3 6.4 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-CHY PF05495.12 EGG08633.1 - 6.9 7.2 9.1 21 5.7 1.2 3.1 2 1 1 3 3 3 0 CHY zinc finger Zn_Tnp_IS1595 PF12760.7 EGG08633.1 - 7.6 6.6 5.9 2 8.5 0.1 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain FGGY_N PF00370.21 EGG08637.1 - 2.8e-10 40.2 0.1 2.3e-07 30.7 0.0 3.0 3 0 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EGG08637.1 - 0.035 13.8 0.1 0.11 12.2 0.0 1.8 3 0 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain DPBB_1 PF03330.18 EGG08638.1 - 3.5e-06 27.2 1.0 8e-06 26.1 0.1 2.0 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 EGG08638.1 - 0.036 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Barwin family Zip PF02535.22 EGG08638.1 - 0.33 10.1 2.3 0.52 9.5 1.6 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter DPBB_1 PF03330.18 EGG08639.1 - 5.1e-07 29.9 0.0 7.4e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EGG08639.1 - 0.0043 16.9 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Barwin family Prok-RING_4 PF14447.6 EGG08639.1 - 0.06 13.2 0.2 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PPR_2 PF13041.6 EGG08640.1 - 3.3e-20 72.0 0.2 6.8e-07 29.4 0.0 4.7 3 2 2 5 5 5 3 PPR repeat family PPR_1 PF12854.7 EGG08640.1 - 3.1e-13 49.2 2.9 0.00018 21.1 0.0 5.3 5 0 0 5 5 5 4 PPR repeat PPR PF01535.20 EGG08640.1 - 9.3e-11 41.2 7.1 0.32 11.3 0.1 7.4 7 1 0 7 7 7 3 PPR repeat PPR_3 PF13812.6 EGG08640.1 - 2.2e-10 40.4 1.3 7.7e-05 22.7 0.0 3.3 2 2 1 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EGG08640.1 - 0.0052 16.2 0.0 0.54 9.6 0.0 2.2 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP tRNA_synt_1c_R1 PF04558.15 EGG08640.1 - 0.028 14.4 1.4 0.42 10.6 0.2 2.2 1 1 1 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 GatB_Yqey PF02637.18 EGG08640.1 - 0.084 12.8 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 GatB domain MCM6_C PF18263.1 EGG08640.1 - 0.15 12.3 1.5 0.15 12.3 0.4 1.6 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain Inhibitor_I29 PF08246.12 EGG08640.1 - 0.19 12.2 1.1 1.2 9.7 0.3 2.1 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) HCO3_cotransp PF00955.21 EGG08643.1 - 4.2e-61 207.3 8.0 1.8e-31 109.6 4.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family F-box-like PF12937.7 EGG08647.1 - 0.092 12.7 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 F-box-like GDP_Man_Dehyd PF16363.5 EGG08648.1 - 0.1 11.9 1.4 0.13 11.6 1.4 1.0 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase LMBR1 PF04791.16 EGG08648.1 - 0.2 10.5 0.2 0.24 10.3 0.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2076 PF09849.9 EGG08650.1 - 0.23 11.5 17.1 0.31 11.0 17.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Zn_clus PF00172.18 EGG08651.1 - 4.7e-05 23.4 2.8 6.6e-05 22.9 2.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1071 PF06378.11 EGG08651.1 - 0.28 10.7 1.8 0.41 10.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1071) Sec3_C PF09763.9 EGG08652.1 - 0.0013 17.3 1.9 0.0016 16.9 1.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Tropomyosin PF00261.20 EGG08652.1 - 0.012 15.0 4.7 0.017 14.5 4.7 1.2 1 0 0 1 1 1 0 Tropomyosin ADIP PF11559.8 EGG08652.1 - 0.045 13.8 1.6 0.15 12.2 0.6 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 EGG08652.1 - 0.17 12.4 4.0 0.39 11.2 3.4 2.0 1 1 0 1 1 1 0 Cell division protein ZapB Tropomyosin_1 PF12718.7 EGG08652.1 - 0.28 11.4 9.0 0.39 10.9 1.7 2.3 1 1 1 2 2 2 0 Tropomyosin like ATG16 PF08614.11 EGG08652.1 - 0.39 10.9 6.1 0.13 12.5 3.1 1.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF16 PF01519.16 EGG08652.1 - 0.4 11.2 6.1 1.8 9.1 2.5 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 EGG08652.1 - 0.74 10.5 6.6 5.5 7.7 0.3 2.3 1 1 1 2 2 2 0 SlyX bZIP_2 PF07716.15 EGG08652.1 - 3.9 7.6 5.4 39 4.4 0.1 2.9 2 1 1 3 3 3 0 Basic region leucine zipper ABC2_membrane PF01061.24 EGG08656.1 - 8e-48 162.6 16.1 1.2e-47 162.0 16.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGG08656.1 - 7.3e-24 84.8 0.1 1.2e-23 84.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGG08656.1 - 3.5e-05 23.1 17.3 3.5e-05 23.1 17.3 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGG08656.1 - 0.0007 19.5 0.3 0.0012 18.8 0.3 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGG08656.1 - 0.0029 18.0 0.1 0.0054 17.1 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG08656.1 - 0.0032 17.7 0.6 0.053 13.8 0.4 2.8 3 1 0 3 3 2 1 AAA domain AAA_18 PF13238.6 EGG08656.1 - 0.0042 17.6 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGG08656.1 - 0.0049 17.1 0.1 0.008 16.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EGG08656.1 - 0.0051 16.7 0.1 0.19 11.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EGG08656.1 - 0.012 15.3 0.1 0.072 12.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGG08656.1 - 0.019 14.7 0.4 0.048 13.4 0.4 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGG08656.1 - 0.038 14.1 0.2 0.088 12.9 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 EGG08656.1 - 0.045 14.3 0.0 0.074 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGG08656.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MobB PF03205.14 EGG08656.1 - 0.16 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 EGG08656.1 - 0.17 11.8 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 EGG08656.1 - 0.17 11.6 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGG08656.1 - 0.32 10.0 0.7 0.53 9.3 0.7 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein WD40 PF00400.32 EGG08658.1 - 1.6e-38 130.0 26.5 1.4e-07 32.1 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG08658.1 - 3.6e-16 59.2 6.6 0.0083 16.4 0.0 6.3 4 3 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGG08658.1 - 4e-05 22.9 0.9 0.00012 21.3 0.3 1.9 1 1 1 2 2 2 1 Coatomer WD associated region JAB PF01398.21 EGG08659.1 - 0.00096 19.1 0.0 0.0028 17.6 0.0 1.7 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2976 PF11190.8 EGG08660.1 - 0.17 11.7 7.2 2.5 7.9 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) Macoilin PF09726.9 EGG08661.1 - 0.28 9.7 9.1 0.32 9.5 9.1 1.0 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 EGG08661.1 - 0.62 9.6 17.7 0.99 9.0 17.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 EGG08661.1 - 1 8.6 25.4 1.2 8.4 25.4 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EGG08661.1 - 3.1 5.9 21.1 3.6 5.7 21.1 1.0 1 0 0 1 1 1 0 Nop14-like family SPX PF03105.19 EGG08661.1 - 3.7 7.4 16.5 4.2 7.2 16.5 1.1 1 0 0 1 1 1 0 SPX domain Peroxin-3 PF04882.12 EGG08661.1 - 5.8 5.8 6.8 6.2 5.7 6.8 1.2 1 0 0 1 1 1 0 Peroxin-3 Sad1_UNC PF07738.13 EGG08664.1 - 2.9e-27 95.3 0.0 4.6e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal PDEase_II PF02112.15 EGG08667.1 - 1.5e-41 142.7 1.0 2.6e-41 141.9 1.0 1.3 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 EGG08667.1 - 0.0068 16.4 0.0 0.017 15.1 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGG08667.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Glyco_hydro_71 PF03659.14 EGG08669.1 - 3.4e-111 371.7 4.1 4.3e-111 371.4 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_99 PF16317.5 EGG08669.1 - 0.0048 16.0 0.1 0.0076 15.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 BRD4_CDT PF17105.5 EGG08669.1 - 0.69 9.6 2.3 0.9 9.2 0.2 2.0 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 CxC1 PF18802.1 EGG08671.1 - 8.2e-13 48.4 0.1 2e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG08671.1 - 0.057 13.6 0.1 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 CxC2 like cysteine cluster associated with KDZ transposases UPF0227 PF05728.12 EGG08671.1 - 0.11 12.5 0.3 0.25 11.3 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Sigma70_ner PF04546.13 EGG08671.1 - 0.16 11.9 4.1 0.069 13.0 1.1 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-C2H2 PF00096.26 EGG08673.1 - 2.4e-11 43.4 3.9 5.3e-05 23.4 1.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG08673.1 - 2.4e-06 27.7 0.1 2.4e-06 27.7 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG08673.1 - 1e-05 25.9 3.4 0.051 14.4 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGG08673.1 - 0.0034 17.3 0.9 0.0034 17.3 0.9 2.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGG08673.1 - 0.013 15.8 4.7 0.048 14.0 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NUDE_C PF04880.13 EGG08673.1 - 0.58 10.6 6.1 1 9.8 6.1 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region zf-met PF12874.7 EGG08673.1 - 0.81 10.2 5.5 3 8.3 0.4 2.9 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-UBP PF02148.19 EGG08673.1 - 0.91 9.9 11.1 44 4.5 11.1 2.3 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Sfi1 PF08457.10 EGG08675.1 - 3.8e-08 32.3 105.7 1.4e-06 27.2 95.7 4.0 1 1 1 2 2 2 1 Sfi1 spindle body protein Myosin_TH1 PF06017.13 EGG08675.1 - 0.43 10.2 5.9 6.3 6.4 0.0 3.5 2 1 1 3 3 3 0 Unconventional myosin tail, actin- and lipid-binding KDZ PF18758.1 EGG08677.1 - 0.00024 20.8 0.1 0.00048 19.8 0.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase FdhE PF04216.12 EGG08677.1 - 0.016 15.1 3.8 0.023 14.6 0.5 2.0 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation ABC_tran_CTD PF16326.5 EGG08677.1 - 0.069 13.4 0.0 0.069 13.4 0.0 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain FTA4 PF13093.6 EGG08677.1 - 1.9 8.3 8.9 4 7.3 8.9 1.6 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Retrotran_gag_2 PF14223.6 EGG08679.1 - 1.1e-05 25.1 0.1 2e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PSP1 PF04468.12 EGG08679.1 - 0.091 13.0 0.0 0.98 9.7 0.0 2.2 2 0 0 2 2 2 0 PSP1 C-terminal conserved region WD40 PF00400.32 EGG08680.1 - 1.9e-34 117.1 12.5 1.4e-06 28.9 1.4 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.12 EGG08680.1 - 1.1e-33 117.0 0.9 1.1e-33 117.0 0.9 4.6 4 1 0 4 4 4 1 Striatin family ANAPC4_WD40 PF12894.7 EGG08680.1 - 1.6e-05 25.1 0.6 0.026 14.8 0.0 4.3 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4746 PF15928.5 EGG08680.1 - 2 7.8 10.3 5.2 6.4 10.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SUFU_C PF12470.8 EGG08680.1 - 2.3 8.2 11.1 7.1 6.6 11.1 1.8 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Membralin PF09746.9 EGG08680.1 - 4.5 6.2 8.7 9.6 5.1 8.7 1.5 1 0 0 1 1 1 0 Tumour-associated protein LRR_4 PF12799.7 EGG08681.1 - 0.019 15.4 3.4 1.1 9.7 0.1 3.4 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Swm2 PF17083.5 EGG08681.1 - 0.17 11.9 0.1 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Nucleolar protein Swm2 PPTA PF01239.22 EGG08682.1 - 1.6e-36 123.0 16.6 3.6e-10 39.2 0.3 4.5 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat GRDP-like PF07173.12 EGG08688.1 - 5.2e-11 43.4 0.0 1.4e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like Aminotran_1_2 PF00155.21 EGG08688.1 - 1.4e-09 37.7 0.0 2.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II VbhA PF18495.1 EGG08689.1 - 0.26 11.2 0.9 0.5 10.3 0.1 1.8 2 0 0 2 2 2 0 Antitoxin VbhA GxDLY PF14607.6 EGG08690.1 - 0.19 11.5 0.7 0.39 10.5 0.4 1.6 1 1 1 2 2 2 0 N-terminus of Esterase_SGNH_hydro-type Corona_nucleoca PF00937.18 EGG08692.1 - 0.00036 19.7 3.4 0.00042 19.5 3.4 1.1 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein KELK PF15796.5 EGG08692.1 - 0.043 14.3 0.4 0.043 14.3 0.4 1.6 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SDP_N PF12278.8 EGG08692.1 - 6.4 6.9 9.6 18 5.5 5.2 2.2 2 0 0 2 2 2 0 Sex determination protein N terminal PAS_12 PF18095.1 EGG08693.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain CxC1 PF18802.1 EGG08696.1 - 7.8e-29 99.9 0.0 1.4e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGG08696.1 - 1.1e-19 71.0 0.0 2e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EGG08696.1 - 4.2e-06 26.9 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases mCpol PF18182.1 EGG08700.1 - 0.012 15.9 0.6 0.024 14.9 0.6 1.5 1 0 0 1 1 1 0 minimal CRISPR polymerase domain DUF4298 PF14131.6 EGG08700.1 - 0.13 12.2 2.1 0.33 10.9 1.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) WXG100 PF06013.12 EGG08700.1 - 0.8 10.0 4.6 0.68 10.2 2.2 2.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG SE PF08491.10 EGG08701.1 - 1.4e-92 309.7 0.0 4.1e-92 308.1 0.0 1.7 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 EGG08701.1 - 1e-08 35.2 0.0 2.2e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGG08701.1 - 0.00023 20.5 0.0 0.36 10.0 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGG08701.1 - 0.00047 20.3 0.0 0.0015 18.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGG08701.1 - 0.0098 15.0 0.0 0.061 12.4 0.0 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGG08701.1 - 0.015 14.4 0.0 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 EGG08701.1 - 0.017 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGG08701.1 - 0.034 13.0 0.0 0.15 10.9 0.0 2.0 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.17 EGG08701.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EGG08701.1 - 0.1 11.6 0.0 2.1 7.3 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pribosyltran_N PF13793.6 EGG08702.1 - 4.1e-45 152.5 0.0 4.7e-44 149.1 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGG08702.1 - 2e-33 116.0 0.4 3.4e-33 115.2 0.1 1.5 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGG08702.1 - 2.2e-16 59.8 0.1 3.3e-15 55.9 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGG08702.1 - 0.0044 16.5 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase F-box-like PF12937.7 EGG08705.1 - 0.00093 19.0 0.6 0.0017 18.2 0.6 1.5 1 0 0 1 1 1 1 F-box-like SPX PF03105.19 EGG08705.1 - 0.47 10.3 6.2 0.73 9.7 6.2 1.2 1 0 0 1 1 1 0 SPX domain Asp PF00026.23 EGG08706.1 - 1.2e-50 172.7 3.3 6e-50 170.4 3.3 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG08706.1 - 1.6e-09 38.3 11.6 2.3e-09 37.8 3.2 3.6 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGG08706.1 - 0.035 14.7 0.8 0.64 10.7 0.1 3.0 2 1 0 2 2 2 0 Aspartyl protease Phage_int_SAM_4 PF13495.6 EGG08708.1 - 0.034 14.6 0.0 0.072 13.6 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Cyclase_polyket PF04673.12 EGG08709.1 - 0.06 13.6 1.1 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Polyketide synthesis cyclase PgdA_N PF18627.1 EGG08709.1 - 0.78 9.3 5.0 0.22 11.1 0.3 2.3 3 0 0 3 3 3 0 Peptidoglycan GlcNAc deacetylase N-terminal domain BolA PF01722.18 EGG08710.1 - 1.4e-11 44.5 0.1 1.8e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 BolA-like protein Nop25 PF09805.9 EGG08713.1 - 1.7e-20 73.9 15.4 1.7e-20 73.9 15.4 2.7 3 0 0 3 3 3 1 Nucleolar protein 12 (25kDa) ALC PF17527.2 EGG08713.1 - 0.00072 19.2 3.5 0.00072 19.2 3.5 1.9 2 1 0 2 2 2 1 Phage ALC protein R3H PF01424.22 EGG08714.1 - 1.7e-09 37.6 0.1 4.4e-09 36.2 0.1 1.8 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 EGG08714.1 - 1.1e-06 28.3 0.1 5.5e-06 26.1 0.1 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.7 EGG08714.1 - 0.0016 18.4 0.3 0.02 14.9 0.1 2.7 2 0 0 2 2 2 1 SUZ-C motif MBF1 PF08523.10 EGG08715.1 - 1.1e-22 80.3 1.0 2e-22 79.4 1.0 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EGG08715.1 - 4.5e-11 42.6 0.1 9e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EGG08715.1 - 4.3e-05 23.8 0.0 0.00017 21.9 0.0 1.9 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 EGG08715.1 - 0.00026 21.0 0.0 0.00038 20.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 EGG08715.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain PSI_integrin PF17205.3 EGG08716.1 - 0.082 12.7 8.2 0.35 10.6 0.2 2.8 2 0 0 2 2 2 0 Integrin plexin domain zf-C3HC4_3 PF13920.6 EGG08716.1 - 0.26 11.2 13.7 0.48 10.3 2.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CIAPIN1 PF05093.13 EGG08718.1 - 4.2e-29 101.0 4.0 4.2e-29 101.0 4.0 1.6 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EGG08718.1 - 1e-09 38.7 0.0 1.8e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Sec63 PF02889.16 EGG08721.1 - 1.8e-28 99.4 1.0 2.6e-28 98.9 1.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EGG08721.1 - 2.5e-19 69.7 0.0 8.2e-19 68.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG08721.1 - 2.9e-08 34.0 0.0 1.6e-07 31.7 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG08721.1 - 3.7e-08 33.6 0.0 1.8e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGG08721.1 - 0.01 16.2 0.0 0.034 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Isy1 PF06246.12 EGG08721.1 - 0.015 14.9 0.1 0.015 14.9 0.1 1.7 2 0 0 2 2 2 0 Isy1-like splicing family UvrD-helicase PF00580.21 EGG08721.1 - 0.066 12.7 0.0 5.6 6.4 0.0 2.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Forkhead PF00250.18 EGG08722.1 - 1.5e-31 108.5 0.0 1.6e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain AC_N PF16214.5 EGG08723.1 - 0.45 9.6 3.5 0.48 9.5 3.5 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region XAP5 PF04921.14 EGG08723.1 - 2.9 7.6 8.0 3.1 7.6 8.0 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator Pex14_N PF04695.13 EGG08723.1 - 7 7.3 8.6 8 7.1 8.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ANAPC4_WD40 PF12894.7 EGG08724.1 - 0.038 14.3 0.0 0.14 12.5 0.0 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Polysacc_deac_1 PF01522.21 EGG08725.1 - 2.6e-28 98.4 0.0 4.2e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGG08725.1 - 9.8e-06 25.0 0.0 0.00013 21.3 0.0 2.2 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 EGG08725.1 - 3.7e-05 23.5 0.0 0.00011 21.9 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) RAP PF08373.10 EGG08725.1 - 0.025 14.7 0.0 7.7 6.7 0.0 2.7 2 0 0 2 2 2 0 RAP domain GFRP PF06399.13 EGG08725.1 - 0.091 12.7 0.0 14 5.6 0.0 2.4 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Head_binding PF09008.10 EGG08725.1 - 0.11 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Head binding Peroxidase_2 PF01328.17 EGG08726.1 - 2.5e-43 148.8 0.0 3.2e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Arg_decarb_HB PF17810.1 EGG08729.1 - 0.018 15.3 0.0 0.18 12.0 0.0 2.5 2 0 0 2 2 2 0 Arginine decarboxylase helical bundle domain PalH PF08733.10 EGG08736.1 - 0.88 8.5 16.8 1.4 7.9 16.8 1.2 1 0 0 1 1 1 0 PalH/RIM21 Doppel PF11466.8 EGG08740.1 - 0.043 13.5 0.2 0.097 12.3 0.2 1.6 1 0 0 1 1 1 0 Prion-like protein Doppel DND1_DSRM PF14709.7 EGG08742.1 - 0.065 13.5 0.1 3 8.1 0.1 2.5 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 CmcI PF04989.12 EGG08742.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase HisK_sensor PF18698.1 EGG08743.1 - 0.099 13.0 0.5 0.24 11.8 0.5 1.7 1 0 0 1 1 1 0 Histidine kinase sensor domain CelTOS PF18659.1 EGG08744.1 - 0.1 13.0 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites HALZ PF02183.18 EGG08746.1 - 0.58 10.4 2.2 2.5 8.4 0.4 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-CCHC_4 PF14392.6 EGG08748.1 - 0.11 12.2 2.3 0.19 11.5 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Mago-bind PF09282.10 EGG08749.1 - 0.014 15.3 1.2 5.2 7.0 0.1 2.4 2 0 0 2 2 2 0 Mago binding SspK PF08176.12 EGG08749.1 - 0.43 10.9 1.2 37 4.7 0.1 2.5 2 0 0 2 2 2 0 Small acid-soluble spore protein K family NIF PF03031.18 EGG08750.1 - 5.5e-20 71.7 0.0 1e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 EGG08750.1 - 0.00019 21.3 0.1 0.00057 19.8 0.1 1.8 1 1 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 EGG08750.1 - 0.045 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG08750.1 - 0.055 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF3144 PF11342.8 EGG08751.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) Bromodomain PF00439.25 EGG08753.1 - 1.4e-22 79.6 0.3 3.5e-22 78.3 0.3 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EGG08753.1 - 5e-09 36.4 0.1 8.7e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG08753.1 - 3.3e-07 30.3 0.1 7.4e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG08753.1 - 5.3e-05 23.6 0.3 0.00012 22.4 0.3 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RNase_H_2 PF13482.6 EGG08754.1 - 0.087 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 RNase_H superfamily SNF2_N PF00176.23 EGG08757.1 - 7.6e-26 90.6 0.6 1.2e-25 90.0 0.6 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGG08757.1 - 0.046 13.7 0.5 0.077 13.0 0.1 1.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGG08758.1 - 0.00023 21.5 0.0 0.00037 20.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC_3 PF13917.6 EGG08759.1 - 0.00055 19.8 0.6 0.0009 19.2 0.6 1.3 1 0 0 1 1 1 1 Zinc knuckle Peptidase_C48 PF02902.19 EGG08760.1 - 0.00029 20.7 0.4 0.00044 20.1 0.1 1.5 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Inositol_P PF00459.25 EGG08762.1 - 6.8e-20 71.7 0.0 1.3e-17 64.2 0.0 2.5 1 1 1 2 2 2 2 Inositol monophosphatase family Tox-ART-HYD1 PF15633.6 EGG08762.1 - 0.064 13.9 0.1 1.1 10.0 0.0 2.3 2 0 0 2 2 2 0 HYD1 signature containing ADP-ribosyltransferase La PF05383.17 EGG08763.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 La domain Peptidase_C48 PF02902.19 EGG08764.1 - 2.8e-12 47.0 0.7 3.6e-12 46.6 0.7 1.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Agarase_CBM PF17992.1 EGG08764.1 - 0.015 14.9 0.2 0.026 14.1 0.2 1.4 1 1 0 1 1 1 0 Agarase CBM like domain zf-ribbon_3 PF13248.6 EGG08764.1 - 0.13 11.8 2.8 4.9 6.7 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TPR_10 PF13374.6 EGG08765.1 - 0.69 9.9 2.6 7.1 6.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3222 PF11519.8 EGG08769.1 - 0.037 14.2 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) DUF1299 PF06975.11 EGG08770.1 - 2.2 8.4 4.4 0.47 10.6 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) RunxI PF08504.11 EGG08771.1 - 0.043 14.5 2.6 0.073 13.8 2.6 1.4 1 0 0 1 1 1 0 Runx inhibition domain Serglycin PF04360.12 EGG08771.1 - 0.15 12.0 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Serglycin DUF5598 PF18127.1 EGG08773.1 - 0.16 12.4 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5598) Imp-YgjV PF10688.9 EGG08776.1 - 0.038 13.8 1.7 0.073 12.9 1.7 1.4 1 0 0 1 1 1 0 Bacterial inner membrane protein DUF1427 PF07235.11 EGG08776.1 - 0.057 13.4 0.8 0.12 12.3 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) MMR_HSR1 PF01926.23 EGG08778.1 - 3.4e-16 59.3 0.0 7.5e-15 55.0 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG08778.1 - 4.1e-06 26.8 0.2 0.0046 16.9 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGG08778.1 - 4.2e-06 26.4 0.0 2.4e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B SDA1 PF05285.12 EGG08778.1 - 0.00048 19.7 5.2 0.0013 18.2 5.4 1.5 2 0 0 2 2 2 1 SDA1 Sporozoite_P67 PF05642.11 EGG08778.1 - 0.00049 18.3 3.0 0.00073 17.8 3.0 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen AIG1 PF04548.16 EGG08778.1 - 0.05 12.9 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 EGG08778.1 - 0.058 13.4 0.1 0.19 11.8 0.1 1.9 1 0 0 1 1 1 0 Dynamin family MeaB PF03308.16 EGG08778.1 - 0.2 10.6 0.5 0.37 9.7 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB WD40 PF00400.32 EGG08781.1 - 3.3e-06 27.7 8.0 0.61 11.0 0.1 5.7 6 1 0 6 6 6 3 WD domain, G-beta repeat Pkinase PF00069.25 EGG08782.1 - 1.2e-71 241.2 0.0 2e-71 240.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG08782.1 - 1.7e-47 161.9 0.0 2.7e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG08782.1 - 1.7e-05 24.3 0.0 0.00047 19.6 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGG08782.1 - 0.002 16.9 0.0 0.0044 15.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Abhydrolase_1 PF00561.20 EGG08783.1 - 1.2e-16 61.2 0.1 1.8e-14 54.0 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG08783.1 - 7.9e-11 41.7 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG08783.1 - 4.3e-05 24.2 0.0 5.3e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EGG08783.1 - 0.1 12.4 0.0 0.58 9.9 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 EGG08783.1 - 0.12 10.9 0.1 0.58 8.6 0.1 2.0 2 1 1 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II LTV PF04180.14 EGG08785.1 - 3.8e-73 247.4 14.4 3.8e-73 247.4 14.4 3.2 1 1 2 3 3 3 2 Low temperature viability protein LRR_4 PF12799.7 EGG08786.1 - 0.71 10.4 6.1 4.9 7.7 3.4 2.9 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) Voltage_CLC PF00654.20 EGG08787.1 - 4.7e-87 292.5 28.0 4.7e-87 292.5 28.0 1.8 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGG08787.1 - 2.1e-06 28.1 0.2 0.00026 21.4 0.0 2.6 2 0 0 2 2 2 1 CBS domain Defensin_RK-1 PF17860.1 EGG08787.1 - 0.06 13.8 0.9 0.14 12.7 0.9 1.6 1 0 0 1 1 1 0 RK-1-like defensin Kelch_4 PF13418.6 EGG08788.1 - 4.9e-39 132.1 10.1 7.9e-08 32.2 0.1 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG08788.1 - 1.4e-30 104.7 4.8 8.5e-06 25.6 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGG08788.1 - 7.2e-30 102.7 8.1 1.1e-07 32.0 0.1 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EGG08788.1 - 1.3e-28 98.3 12.5 1.5e-07 31.4 0.3 6.7 4 2 2 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EGG08788.1 - 1.1e-27 95.3 5.8 3e-09 36.3 0.2 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGG08788.1 - 4.8e-23 80.2 14.1 4.6e-05 23.2 0.1 7.1 7 0 0 7 7 7 5 Kelch motif HrpB7 PF09486.10 EGG08788.1 - 0.0075 16.7 13.0 0.0075 16.7 13.0 5.7 4 2 0 4 4 4 1 Bacterial type III secretion protein (HrpB7) DUF1668 PF07893.13 EGG08788.1 - 0.015 14.7 0.1 0.015 14.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) RAG2 PF03089.14 EGG08788.1 - 0.026 13.5 0.0 0.63 9.0 0.0 3.0 3 1 1 4 4 4 0 Recombination activating protein 2 DUF948 PF06103.11 EGG08788.1 - 4.2 7.7 20.1 0.64 10.3 0.9 4.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) GCM PF03615.15 EGG08789.1 - 6.6e-05 22.8 1.5 0.0002 21.2 0.6 2.1 2 0 0 2 2 2 1 GCM motif protein LtuB PF17455.2 EGG08789.1 - 0.08 13.6 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Late transcription unit B Nop14 PF04147.12 EGG08792.1 - 3.6 5.7 34.2 6.6 4.8 34.2 1.3 1 0 0 1 1 1 0 Nop14-like family EMC3_TMCO1 PF01956.16 EGG08792.1 - 7.5 6.3 7.1 14 5.4 7.1 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like eIF3_subunit PF08597.10 EGG08794.1 - 0.00023 21.2 8.6 0.00028 20.9 8.6 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit UbiA PF01040.18 EGG08799.1 - 0.059 12.7 0.0 0.059 12.7 0.0 1.0 1 0 0 1 1 1 0 UbiA prenyltransferase family Cyt-b5 PF00173.28 EGG08802.1 - 0.011 15.8 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain DUF294_C PF10335.9 EGG08802.1 - 0.095 12.5 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain TPR_19 PF14559.6 EGG08807.1 - 3.6e-06 27.4 0.0 0.12 12.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.31 EGG08807.1 - 0.00026 21.1 0.0 0.0011 19.0 0.0 2.2 1 0 0 1 1 1 1 DnaJ domain ANAPC3 PF12895.7 EGG08807.1 - 0.0086 16.3 0.5 3.5 7.9 0.0 3.5 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF4420 PF14390.6 EGG08809.1 - 0.083 12.1 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) TRP PF06011.12 EGG08810.1 - 2.1e-34 119.0 11.6 9.2e-34 116.9 11.6 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel CDV3 PF15359.6 EGG08810.1 - 4.8 7.7 12.7 0.21 12.1 1.3 2.7 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 Pkinase PF00069.25 EGG08813.1 - 5.3e-72 242.3 0.0 1.3e-71 241.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG08813.1 - 2.9e-33 115.3 0.0 6e-32 110.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG08813.1 - 0.00093 18.6 2.2 0.077 12.3 0.7 2.4 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 EGG08813.1 - 0.00094 18.8 0.8 0.0014 18.2 0.8 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGG08813.1 - 0.0076 16.2 0.0 0.09 12.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGG08813.1 - 0.0079 15.0 0.0 0.0097 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase NPC1_N PF16414.5 EGG08814.1 - 7.2e-74 248.4 16.3 3.4e-73 246.2 16.3 2.0 1 1 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EGG08814.1 - 2.9e-63 214.2 5.8 6.5e-35 120.5 0.5 3.1 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 EGG08814.1 - 1.5e-43 148.3 11.8 6e-24 84.6 0.0 3.3 3 1 1 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 EGG08814.1 - 0.13 9.9 10.3 0.22 9.1 10.3 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family IDEAL PF08858.10 EGG08815.1 - 0.089 12.5 0.6 2.9 7.7 0.1 2.5 2 0 0 2 2 2 0 IDEAL domain tRNA-synt_1c PF00749.21 EGG08817.1 - 4.4e-91 305.0 0.0 5.5e-91 304.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain eIF-5_eIF-2B PF01873.17 EGG08818.1 - 3.4e-40 136.6 0.0 7.5e-40 135.4 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EGG08818.1 - 1.2e-20 73.4 1.4 3.6e-20 71.9 0.1 2.4 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF2387 PF09526.10 EGG08818.1 - 0.14 12.3 1.7 0.24 11.6 0.4 2.1 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) PC-Esterase PF13839.6 EGG08822.1 - 0.0048 16.7 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p MitMem_reg PF13012.6 EGG08823.1 - 9.3e-32 109.8 0.3 1.8e-31 108.8 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGG08823.1 - 1.9e-25 89.1 0.0 1.3e-11 44.5 0.0 2.5 1 1 1 2 2 2 2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pex2_Pex12 PF04757.14 EGG08824.1 - 1.7e-25 90.0 16.4 3.6e-25 88.9 16.3 1.5 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region SUI1 PF01253.22 EGG08825.1 - 2.4e-19 69.6 0.0 4.6e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 EGG08825.1 - 5e-10 39.9 0.0 1.4e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EGG08825.1 - 0.00041 20.3 0.0 0.00089 19.2 0.0 1.4 1 0 0 1 1 1 1 PUA domain Tannase PF07519.11 EGG08828.1 - 4.5e-80 269.8 0.0 9.4e-79 265.5 0.0 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase DUF4217 PF13959.6 EGG08830.1 - 0.47 10.7 2.0 0.88 9.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) Tannase PF07519.11 EGG08831.1 - 1.3e-91 307.9 0.0 1.5e-91 307.6 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Metallothio PF00131.20 EGG08832.1 - 9 6.5 13.8 12 6.1 7.6 3.0 2 0 0 2 2 2 0 Metallothionein Kelch_4 PF13418.6 EGG08833.1 - 8.3e-18 64.1 8.2 0.00061 19.7 0.1 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EGG08833.1 - 1.1e-09 38.3 16.5 0.054 13.8 0.1 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG08833.1 - 5.7e-09 35.8 7.4 0.0027 17.6 0.2 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 EGG08833.1 - 2.5e-05 24.4 9.9 0.59 10.5 0.0 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 EGG08833.1 - 0.0082 15.7 9.3 5.9 6.6 0.0 5.8 7 0 0 7 7 7 1 Kelch motif DUF3040 PF11239.8 EGG08833.1 - 0.027 14.8 0.5 0.55 10.6 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) RasGAP PF00616.19 EGG08833.1 - 6.2 6.5 7.2 1.9 8.2 0.2 2.5 2 1 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Pkinase PF00069.25 EGG08834.1 - 3.6e-28 98.6 0.0 4.1e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG08834.1 - 3.2e-21 75.8 0.0 3.6e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG08834.1 - 0.00061 18.7 0.3 0.00088 18.1 0.3 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGG08834.1 - 0.011 15.6 0.1 0.013 15.4 0.1 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG08834.1 - 0.012 14.9 1.1 0.19 11.1 0.0 2.0 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGG08834.1 - 0.097 12.0 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 EGG08835.1 - 3.7e-12 46.2 0.0 4.4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG08835.1 - 3e-09 36.5 0.0 3e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase JmjC PF02373.22 EGG08836.1 - 5e-13 49.5 0.6 1.5e-12 47.9 0.1 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase ZZ PF00569.17 EGG08836.1 - 0.0057 16.4 4.3 0.0057 16.4 4.3 1.9 2 0 0 2 2 2 1 Zinc finger, ZZ type ARF7EP_C PF14949.6 EGG08836.1 - 0.0082 16.7 4.7 0.36 11.5 0.5 2.7 2 0 0 2 2 2 2 ARF7 effector protein C-terminus C1_1 PF00130.22 EGG08836.1 - 0.015 15.1 2.2 0.015 15.1 2.2 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cupin_8 PF13621.6 EGG08836.1 - 0.019 14.7 3.6 0.26 11.0 0.1 3.1 2 1 0 2 2 2 0 Cupin-like domain PBP1_TM PF14812.6 EGG08836.1 - 0.68 10.3 3.2 11 6.5 2.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FNIP_C PF14638.6 EGG08837.1 - 0.018 14.7 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus DUF3810 PF12725.7 EGG08837.1 - 3.6 6.9 11.5 8.3 5.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Cyclin_N PF00134.23 EGG08838.1 - 2.4e-11 43.5 0.0 4.9e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGG08838.1 - 5.8 7.0 7.6 1.7 8.7 0.2 3.1 3 2 0 3 3 3 0 Cyclin, C-terminal domain Retrotran_gag_2 PF14223.6 EGG08839.1 - 0.00051 19.7 0.2 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGG08839.1 - 0.13 12.1 0.0 0.39 10.6 0.0 1.9 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MFS_1 PF07690.16 EGG08840.1 - 2.3e-38 132.1 35.7 2.3e-38 132.1 35.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGG08840.1 - 1.6e-07 31.0 14.1 2.4e-07 30.4 0.5 3.2 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 EGG08840.1 - 1.3e-05 23.9 1.3 1.3e-05 23.9 1.3 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EGG08840.1 - 0.00059 18.3 0.1 0.00059 18.3 0.1 3.4 2 2 2 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family Pex14_N PF04695.13 EGG08840.1 - 8.5 7.0 9.6 0.52 11.0 2.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pox_A21 PF05323.12 EGG08841.1 - 0.046 14.3 2.7 0.76 10.4 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A21 Protein OPT PF03169.15 EGG08842.1 - 7.1e-183 609.6 46.6 8.1e-183 609.4 46.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TMEMspv1-c74-12 PF11044.8 EGG08842.1 - 0.19 11.8 0.0 0.19 11.8 0.0 3.7 4 0 0 4 4 4 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein TPR_2 PF07719.17 EGG08843.1 - 3.7e-09 36.0 7.5 0.64 10.3 0.1 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat Suf PF05843.14 EGG08843.1 - 6.5e-07 29.6 17.4 0.011 15.8 1.4 5.4 4 1 0 5 5 5 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EGG08843.1 - 1.1e-05 25.9 9.5 49 5.1 0.0 8.0 6 3 2 8 8 6 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGG08843.1 - 2.5e-05 24.3 13.9 1.1 9.3 0.1 6.4 6 1 0 6 6 6 3 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 EGG08843.1 - 3.6e-05 24.0 2.3 6.2 7.2 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG08843.1 - 9e-05 22.9 0.2 20 5.8 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGG08843.1 - 0.2 12.1 11.9 2.5 8.7 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGG08843.1 - 0.48 10.3 3.7 14 5.7 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG08843.1 - 0.85 10.4 6.8 25 5.8 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGG08843.1 - 1.1 9.0 3.8 45 3.8 0.1 4.2 5 0 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 EGG08843.1 - 1.3 9.4 14.9 6.9 7.2 0.1 6.8 8 1 0 8 8 7 0 Tetratricopeptide repeat FAM176 PF14851.6 EGG08844.1 - 0.027 14.1 0.4 0.041 13.5 0.4 1.2 1 0 0 1 1 1 0 FAM176 family SPX PF03105.19 EGG08844.1 - 0.44 10.4 8.4 0.63 9.9 8.4 1.2 1 0 0 1 1 1 0 SPX domain DUF4637 PF15470.6 EGG08844.1 - 0.61 9.8 3.8 0.77 9.5 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PBP1_TM PF14812.6 EGG08844.1 - 1.9 8.9 4.6 3.7 8.0 4.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Apt1 PF10351.9 EGG08844.1 - 4.3 6.1 6.5 5.2 5.8 6.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Rrn6 PF10214.9 EGG08844.1 - 6.8 5.0 13.3 9.7 4.5 13.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ribosomal_L27A PF00828.19 EGG08845.1 - 1.9e-21 77.0 0.1 2.8e-21 76.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A zf-C3HC4_3 PF13920.6 EGG08848.1 - 3.3e-05 23.7 8.8 3.3e-05 23.7 8.8 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PROCN PF08083.11 EGG08849.1 - 8e-233 772.4 10.9 1.3e-232 771.7 10.9 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EGG08849.1 - 1e-125 417.9 0.7 2e-125 417.0 0.7 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EGG08849.1 - 2.5e-88 294.0 2.7 7.9e-88 292.4 2.7 2.0 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EGG08849.1 - 1.2e-84 281.8 3.1 1.2e-84 281.8 3.1 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EGG08849.1 - 2.8e-72 241.1 0.1 5.5e-72 240.1 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EGG08849.1 - 5.7e-47 158.0 0.6 1.4e-46 156.7 0.6 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EGG08849.1 - 4.5e-38 129.9 0.0 1.7e-37 128.1 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain Amino_oxidase PF01593.24 EGG08851.1 - 1.4e-23 84.0 0.0 1.8e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGG08851.1 - 3.6e-11 43.1 0.1 1.1e-10 41.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG08851.1 - 7.3e-06 25.8 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGG08851.1 - 0.0017 17.7 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EGG08851.1 - 0.0018 17.6 0.2 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG08851.1 - 0.059 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EGG08851.1 - 0.065 12.1 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MCRA PF06100.11 EGG08851.1 - 0.07 11.9 0.0 0.095 11.5 0.0 1.1 1 0 0 1 1 1 0 MCRA family Pyr_redox PF00070.27 EGG08851.1 - 0.09 13.3 1.7 0.1 13.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CENP-T_C PF15511.6 EGG08852.1 - 4.8e-08 33.1 0.1 5.9e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EGG08852.1 - 8.4e-05 22.7 0.1 0.00012 22.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGG08852.1 - 0.00018 21.9 0.0 0.00023 21.5 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EGG08852.1 - 0.0011 19.4 0.1 0.0012 19.2 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGG08852.1 - 0.0015 18.7 0.1 0.0029 17.8 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGG08852.1 - 0.073 13.2 0.0 0.082 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_L27A PF00828.19 EGG08852.1 - 0.45 11.2 4.0 0.57 10.9 4.0 1.3 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A CPSase_L_D3 PF02787.19 EGG08853.1 - 1.6e-05 25.3 0.5 0.0001 22.7 0.5 2.3 1 1 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ANAPC4_WD40 PF12894.7 EGG08855.1 - 0.00065 19.9 0.1 0.055 13.8 0.1 2.7 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG08855.1 - 0.087 13.7 9.1 3.3 8.7 0.0 4.3 4 1 0 4 4 4 0 WD domain, G-beta repeat PTH2 PF01981.16 EGG08857.1 - 2.7e-43 147.0 0.1 3.4e-43 146.6 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF3255 PF11631.8 EGG08857.1 - 0.044 13.6 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) Glucan_synthase PF02364.15 EGG08858.1 - 0 1308.4 0.0 0 1307.9 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EGG08858.1 - 6.4e-41 139.7 0.1 2e-40 138.1 0.1 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 PACT_coil_coil PF10495.9 EGG08858.1 - 0.2 12.3 0.6 0.65 10.6 0.2 2.0 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF2514 PF10721.9 EGG08859.1 - 0.53 10.3 26.3 0.78 9.8 26.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) SAPS PF04499.15 EGG08859.1 - 2 7.1 5.7 2.6 6.7 5.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4192 PF13830.6 EGG08859.1 - 2.8 7.9 13.4 4.4 7.3 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Presenilin PF01080.17 EGG08859.1 - 2.9 6.5 8.6 4.1 6.1 8.6 1.1 1 0 0 1 1 1 0 Presenilin DDRGK PF09756.9 EGG08859.1 - 3.1 7.4 23.9 4.4 6.8 23.9 1.1 1 0 0 1 1 1 0 DDRGK domain SOBP PF15279.6 EGG08859.1 - 4 7.9 8.8 7.4 7.1 8.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4569 PF15133.6 EGG08859.1 - 4.6 6.9 10.4 6.8 6.3 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) XAP5 PF04921.14 EGG08859.1 - 7.4 6.3 15.8 11 5.7 15.8 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Hid1 PF12722.7 EGG08859.1 - 9.9 4.1 8.5 14 3.7 8.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNase_P_Rpp14 PF01900.19 EGG08860.1 - 0.033 14.4 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 Rpp14/Pop5 family TIP49 PF06068.13 EGG08862.1 - 4.5e-157 522.8 0.2 5.7e-157 522.4 0.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGG08862.1 - 8.7e-26 89.8 0.8 2.4e-25 88.5 0.8 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EGG08862.1 - 9.2e-08 32.6 0.1 0.00012 22.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGG08862.1 - 8.5e-07 28.9 0.2 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EGG08862.1 - 3.9e-06 26.4 0.3 7e-06 25.6 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 EGG08862.1 - 8.9e-05 22.0 1.0 0.0035 16.8 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGG08862.1 - 0.0012 19.3 0.2 0.0088 16.4 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG08862.1 - 0.0042 17.4 0.1 0.2 11.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EGG08862.1 - 0.0061 17.0 1.1 0.012 16.0 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGG08862.1 - 0.0071 16.5 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG08862.1 - 0.025 14.9 1.4 0.86 9.9 1.4 2.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGG08862.1 - 0.029 14.3 0.2 8.2 6.4 0.1 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EGG08862.1 - 0.035 13.7 0.2 0.11 12.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 EGG08862.1 - 0.12 12.7 0.4 0.23 11.7 0.4 1.5 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain Pex19 PF04614.12 EGG08864.1 - 8.9e-62 209.0 8.7 8.9e-62 209.0 8.7 1.5 2 0 0 2 2 2 1 Pex19 protein family Interferon PF00143.19 EGG08864.1 - 0.064 13.4 0.7 15 5.8 0.0 3.1 4 0 0 4 4 4 0 Interferon alpha/beta domain KinB_sensor PF16767.5 EGG08864.1 - 0.088 13.3 0.6 0.69 10.4 0.1 2.4 1 1 1 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB Mito_carr PF00153.27 EGG08865.1 - 3.9e-42 142.1 9.1 5.7e-18 64.6 0.1 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein Apolipoprotein PF01442.18 EGG08865.1 - 0.075 12.9 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1617 PF07761.12 EGG08867.1 - 0.043 13.9 0.2 0.091 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) Hol_Tox PF16935.5 EGG08868.1 - 0.00089 19.3 0.1 0.0021 18.1 0.1 1.6 1 0 0 1 1 1 1 Putative Holin-like Toxin (Hol-Tox) DUF5310 PF17237.2 EGG08868.1 - 0.049 13.5 3.0 0.049 13.5 3.0 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5310) DUF1218 PF06749.12 EGG08868.1 - 2.5 8.7 11.2 6.3 7.4 5.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) UQ_con PF00179.26 EGG08869.1 - 3.2e-47 159.7 0.0 4.1e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGG08869.1 - 0.00027 20.6 0.0 0.00037 20.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGG08869.1 - 0.0067 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 EGG08869.1 - 0.011 16.0 0.0 0.029 14.6 0.0 1.7 2 0 0 2 2 2 0 RWD domain Ribosomal_L2_C PF03947.18 EGG08870.1 - 6.2e-48 162.2 0.7 2.3e-47 160.3 0.9 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGG08870.1 - 6.9e-26 90.0 0.5 3.3e-25 87.9 0.2 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain MFS_1 PF07690.16 EGG08871.1 - 9.7e-31 107.0 24.3 9.7e-31 107.0 24.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily EAP30 PF04157.16 EGG08872.1 - 1.6e-69 233.8 0.0 1.9e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family AbiGi PF10899.8 EGG08872.1 - 0.026 14.4 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Putative abortive phage resistance protein AbiGi, antitoxin DUF4423 PF14394.6 EGG08872.1 - 0.14 11.9 0.2 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) Pex2_Pex12 PF04757.14 EGG08873.1 - 8.1e-29 100.8 5.8 1.4e-28 100.0 5.8 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 EGG08873.1 - 9.6e-06 25.4 0.9 1.7e-05 24.6 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG08873.1 - 0.00014 22.2 2.8 0.00025 21.3 2.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG08873.1 - 0.00022 21.0 1.1 0.00042 20.1 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGG08873.1 - 0.0003 20.9 2.7 0.00085 19.4 2.8 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGG08873.1 - 0.00082 19.4 3.8 0.0017 18.3 3.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG08873.1 - 0.013 15.5 1.5 0.026 14.5 1.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGG08873.1 - 0.023 14.6 0.8 0.036 13.9 0.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RDD PF06271.12 EGG08873.1 - 0.026 14.7 0.1 0.067 13.4 0.0 1.6 2 0 0 2 2 2 0 RDD family zf-rbx1 PF12678.7 EGG08873.1 - 0.037 14.3 0.4 0.087 13.1 0.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain rve PF00665.26 EGG08873.1 - 0.079 13.2 0.1 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain DUF3219 PF11514.8 EGG08874.1 - 0.094 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3219) Malic_M PF03949.15 EGG08875.1 - 3.6e-91 305.0 0.0 4.8e-91 304.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EGG08875.1 - 3e-64 216.2 0.0 4.3e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Aminotran_3 PF00202.21 EGG08876.1 - 1.1e-113 380.0 0.0 1.3e-113 379.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGG08876.1 - 8e-05 22.0 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGG08876.1 - 0.03 13.6 0.0 0.087 12.1 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase Glyco_hydro_71 PF03659.14 EGG08877.1 - 1.7e-64 218.0 0.4 6.2e-37 127.3 0.4 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 71 SEF14_adhesin PF06443.11 EGG08877.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 SEF14-like adhesin Bromodomain PF00439.25 EGG08878.1 - 1.7e-16 60.0 0.0 4e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain DUF1569 PF07606.11 EGG08878.1 - 0.05 13.6 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) Hydantoinase_B PF02538.14 EGG08879.1 - 2.9e-211 702.4 0.0 3.3e-211 702.2 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Methyltransf_12 PF08242.12 EGG08882.1 - 5.2e-13 49.6 0.0 1.2e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG08882.1 - 2.3e-12 47.1 0.0 3.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG08882.1 - 1.2e-10 41.9 0.0 1.9e-09 38.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG08882.1 - 3.4e-07 30.8 0.0 2.9e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG08882.1 - 8.9e-06 25.6 0.0 2.2e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG08882.1 - 0.00019 21.0 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 EGG08882.1 - 0.048 14.7 0.0 0.089 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.11 EGG08882.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TFIIA PF03153.13 EGG08884.1 - 4 7.3 24.5 4.7 7.1 24.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_II_R PF09551.10 EGG08885.1 - 4 7.9 9.4 1.3 9.4 5.0 2.4 2 1 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) PTS_2-RNA PF01885.16 EGG08887.1 - 0.015 15.4 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family RPN6_N PF18055.1 EGG08887.1 - 0.017 15.4 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain PH_10 PF15411.6 EGG08888.1 - 9e-25 87.3 0.0 2.9e-24 85.7 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.6 EGG08888.1 - 3.5e-05 24.0 1.4 7.4e-05 23.0 1.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG08888.1 - 5.9e-05 23.0 0.5 0.00019 21.4 0.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG08888.1 - 0.00048 20.0 1.4 0.0012 18.8 1.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain VWA PF00092.28 EGG08888.1 - 0.00061 20.1 0.0 0.0034 17.6 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGG08888.1 - 0.001 19.0 0.3 0.23 11.4 0.0 2.7 3 0 0 3 3 3 1 von Willebrand factor type A domain zf-RING_11 PF17123.5 EGG08888.1 - 0.014 15.2 4.7 0.01 15.5 2.5 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGG08888.1 - 0.038 13.8 0.7 0.12 12.3 0.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGG08888.1 - 0.064 12.9 1.1 0.14 11.8 1.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EGG08888.1 - 0.17 12.1 0.2 0.33 11.1 0.2 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 EGG08888.1 - 0.29 11.0 3.1 1.2 9.1 3.3 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Histone PF00125.24 EGG08889.1 - 1.2e-51 174.5 2.7 1.3e-51 174.4 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGG08889.1 - 0.0001 22.9 1.1 0.00012 22.6 1.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EGG08889.1 - 0.00015 22.1 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGG08889.1 - 0.00018 21.5 0.5 0.00028 20.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EGG08889.1 - 0.0038 17.5 0.1 0.0038 17.5 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGG08889.1 - 0.035 14.2 0.2 0.055 13.5 0.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PRAI PF00697.22 EGG08889.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase bZIP_2 PF07716.15 EGG08890.1 - 1.7e-06 28.0 9.6 6.5e-06 26.1 6.7 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 EGG08890.1 - 0.00014 21.8 8.4 0.00014 21.8 8.4 2.1 2 0 0 2 2 2 1 bZIP transcription factor TSC22 PF01166.18 EGG08890.1 - 0.009 16.3 0.1 0.018 15.4 0.1 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family MDD_C PF18376.1 EGG08893.1 - 6.3e-65 218.4 0.0 8.5e-65 218.0 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EGG08893.1 - 3e-07 30.5 4.6 9.2e-07 29.0 1.2 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain SARAF PF06682.12 EGG08894.1 - 0.024 14.3 6.1 0.061 13.0 6.1 1.6 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Tub_N PF16322.5 EGG08894.1 - 0.071 13.5 7.3 0.1 13.0 7.3 1.1 1 0 0 1 1 1 0 Tubby N-terminal BUD22 PF09073.10 EGG08894.1 - 0.074 12.4 5.1 0.085 12.2 5.1 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EGG08894.1 - 0.65 9.4 5.4 0.86 9.0 5.4 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 EGG08894.1 - 1.7 7.9 5.3 2.3 7.5 5.3 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EGG08894.1 - 2.1 6.5 7.3 2.7 6.1 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.9 EGG08894.1 - 3.2 6.2 8.2 4.3 5.8 8.2 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EGG08894.1 - 3.8 6.3 7.5 4.8 5.9 7.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 EGG08894.1 - 7.9 6.3 12.3 10 5.9 12.3 1.2 1 0 0 1 1 1 0 SPX domain HTH_Tnp_Tc5 PF03221.16 EGG08897.1 - 2.3e-14 53.2 0.1 3.8e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 EGG08897.1 - 7.9e-07 28.7 0.2 8.2e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain RNA_pol_L_2 PF13656.6 EGG08899.1 - 1.1e-26 92.4 0.1 1.5e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGG08899.1 - 1e-10 40.9 0.0 1.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cytochrom_B561 PF03188.16 EGG08900.1 - 2.3e-14 53.7 6.2 2.3e-14 53.7 6.2 1.9 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 SdpI PF13630.6 EGG08900.1 - 3.5 7.8 16.4 1.2 9.3 1.1 3.4 3 0 0 3 3 3 0 SdpI/YhfL protein family DUF4079 PF13301.6 EGG08900.1 - 5.5 7.1 11.5 1.6 8.9 4.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) SPT16 PF08644.11 EGG08901.1 - 1.1e-51 174.9 1.3 4.4e-51 173.0 0.6 2.5 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EGG08901.1 - 2.2e-47 160.8 2.7 2.6e-47 160.6 0.0 2.6 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EGG08901.1 - 9.9e-25 87.5 0.1 3.4e-24 85.7 0.0 2.0 3 0 0 3 3 3 1 Metallopeptidase family M24 Rtt106 PF08512.12 EGG08901.1 - 2.3e-16 60.0 0.3 1.3e-15 57.5 0.1 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like FtsK_SpoIIIE PF01580.18 EGG08901.1 - 0.028 13.8 0.0 0.073 12.4 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Terminase_4 PF05119.12 EGG08901.1 - 0.039 14.4 2.1 0.47 10.9 0.3 3.1 2 0 0 2 2 2 0 Phage terminase, small subunit Med22 PF06179.12 EGG08904.1 - 0.1 12.8 0.2 0.54 10.5 0.1 1.9 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex Adaptin_N PF01602.20 EGG08905.1 - 1.5e-127 426.3 10.3 1.8e-127 426.1 10.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGG08905.1 - 2.2e-58 196.9 3.1 5e-58 195.7 0.4 2.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGG08905.1 - 2.4e-12 47.1 7.3 4.8e-07 30.1 0.2 4.9 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.22 EGG08905.1 - 2.1e-08 33.7 1.5 0.0081 16.3 0.0 4.7 5 0 0 5 5 4 2 HEAT repeat DUF1548 PF07579.11 EGG08905.1 - 0.0013 19.0 0.7 0.2 12.0 0.0 3.6 3 1 1 4 4 4 1 Domain of Unknown Function (DUF1548) Arm PF00514.23 EGG08905.1 - 0.0035 17.3 0.1 1.5 9.0 0.0 3.3 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EGG08905.1 - 0.0063 16.1 1.4 2.7 7.5 0.0 3.6 3 1 1 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 EGG08905.1 - 0.01 16.3 0.1 4.6 7.9 0.0 3.8 3 0 0 3 3 3 0 HEAT-like repeat RTP1_C1 PF10363.9 EGG08905.1 - 0.013 15.7 4.3 2.2 8.5 0.1 4.3 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm_2 PF04826.13 EGG08905.1 - 0.56 9.6 5.5 0.14 11.6 0.1 2.6 3 0 0 3 3 3 0 Armadillo-like Sec7_N PF12783.7 EGG08905.1 - 0.57 10.1 4.7 1.5 8.7 1.9 2.6 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal zf-AN1 PF01428.16 EGG08906.1 - 3.5e-09 36.7 6.4 7.4e-09 35.6 6.4 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.21 EGG08906.1 - 0.32 11.3 5.7 0.66 10.3 5.7 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Sulfate_transp PF00916.20 EGG08907.1 - 2.3e-80 270.2 15.2 3.5e-80 269.6 15.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGG08907.1 - 3.5e-17 62.1 0.1 6.4e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 STAS domain Diphthamide_syn PF01866.17 EGG08908.1 - 3.3e-91 305.9 0.0 5.3e-56 190.3 0.0 2.6 1 1 0 2 2 2 2 Putative diphthamide synthesis protein Ras PF00071.22 EGG08909.1 - 1.1e-53 181.2 0.1 1.3e-53 180.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG08909.1 - 6.8e-31 107.0 0.0 1.4e-30 105.9 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG08909.1 - 7e-18 64.7 0.0 8.4e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG08909.1 - 1.5e-09 37.7 0.0 1.4e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG08909.1 - 1.4e-08 34.8 0.0 4.1e-08 33.3 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGG08909.1 - 2e-06 27.4 0.1 2.6e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGG08909.1 - 0.0019 17.7 0.0 0.004 16.6 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EGG08909.1 - 0.0039 17.3 0.7 0.013 15.6 0.7 2.1 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 EGG08909.1 - 0.0069 16.3 1.7 2.3 8.1 0.2 2.3 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGG08909.1 - 0.013 15.0 0.1 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B DEAD PF00270.29 EGG08910.1 - 2.5e-46 157.6 0.0 7.6e-45 152.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG08910.1 - 1.8e-27 95.9 0.0 9.1e-27 93.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG08910.1 - 1.9e-05 24.7 0.0 0.00017 21.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MFAP1 PF06991.11 EGG08910.1 - 0.99 9.2 6.7 1 9.2 5.5 1.6 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing Pkinase PF00069.25 EGG08911.1 - 5.7e-57 193.1 0.0 6.8e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG08911.1 - 7.4e-26 91.0 0.0 8.3e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG08911.1 - 0.0052 16.2 0.0 0.0093 15.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGG08911.1 - 0.0061 15.6 0.0 0.0082 15.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Herpes_LMP1 PF05297.11 EGG08912.1 - 2.7 7.1 7.9 3.9 6.6 7.9 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PC-Esterase PF13839.6 EGG08913.1 - 0.033 13.9 0.0 0.082 12.6 0.0 1.7 2 0 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF4015 PF13200.6 EGG08913.1 - 0.32 10.0 0.5 0.75 8.8 0.0 1.7 2 0 0 2 2 2 0 Putative glycosyl hydrolase domain Cas1_AcylT PF07779.12 EGG08914.1 - 9.8e-137 456.7 24.6 1.2e-136 456.4 24.6 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 EGG08914.1 - 0.00015 21.7 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Lipase_GDSL PF00657.22 EGG08914.1 - 0.21 11.5 0.0 6.5 6.7 0.0 2.2 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 EGG08916.1 - 2e-28 99.3 47.2 2e-28 99.3 47.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TssO PF17561.2 EGG08916.1 - 0.34 11.0 0.5 0.76 9.9 0.5 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO IQ_SEC7_PH PF16453.5 EGG08917.1 - 0.012 15.6 0.5 0.012 15.6 0.5 1.9 2 0 0 2 2 2 0 PH domain DDE_3 PF13358.6 EGG08918.1 - 4.2e-08 33.1 0.0 7.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EGG08918.1 - 0.023 15.3 0.1 0.062 13.9 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain AAA_14 PF13173.6 EGG08918.1 - 0.058 13.4 0.2 1.4 9.0 0.1 2.1 1 1 0 2 2 2 0 AAA domain PLA2_B PF01735.18 EGG08921.1 - 3.8e-100 335.6 0.0 5e-100 335.2 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.18 EGG08922.1 - 1.1e-99 334.1 0.0 1.4e-99 333.7 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain HECA PF15353.6 EGG08923.1 - 0.028 14.6 0.0 0.037 14.3 0.0 1.1 1 0 0 1 1 1 0 Headcase protein family homologue DUF3556 PF12077.8 EGG08927.1 - 0.17 10.3 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) Ribosomal_S19e PF01090.19 EGG08929.1 - 0.07 12.8 0.1 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S19e Sad1_UNC PF07738.13 EGG08930.1 - 5.8e-28 97.5 0.0 1.1e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CfAFP PF05264.11 EGG08930.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) HSF_DNA-bind PF00447.17 EGG08932.1 - 3e-30 104.7 2.2 3.9e-30 104.3 2.2 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DUF72 PF01904.18 EGG08932.1 - 0.08 13.0 0.0 0.093 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF72 GEMIN8 PF15348.6 EGG08933.1 - 0.39 11.0 12.1 0.47 10.7 12.1 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF2722 PF10846.8 EGG08933.1 - 0.57 9.1 13.2 0.61 9.0 13.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) ALMT PF11744.8 EGG08933.1 - 0.61 8.8 4.1 0.73 8.6 4.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 EGG08933.1 - 1.3 7.9 7.6 1.6 7.7 7.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 NOA36 PF06524.12 EGG08933.1 - 2.7 7.2 17.5 3 7.1 17.5 1.1 1 0 0 1 1 1 0 NOA36 protein SID-1_RNA_chan PF13965.6 EGG08933.1 - 3.8 5.8 5.3 3.6 5.9 5.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4746 PF15928.5 EGG08933.1 - 4.8 6.5 13.7 5.2 6.4 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4820 PF16091.5 EGG08933.1 - 6.7 6.0 9.6 7.5 5.8 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Astro_capsid_p PF12226.8 EGG08933.1 - 7 5.7 18.6 7.3 5.6 18.6 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 EGG08934.1 - 0.099 10.9 8.8 0.12 10.6 8.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3141 PF11339.8 EGG08934.1 - 0.2 10.1 1.0 0.23 9.9 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Mucin PF01456.17 EGG08934.1 - 0.29 11.1 6.9 0.37 10.8 6.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SR-25 PF10500.9 EGG08934.1 - 4.1 7.0 23.1 5.1 6.6 23.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.7 EGG08934.1 - 7.9 4.5 13.4 9.4 4.2 13.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FA_desaturase PF00487.24 EGG08938.1 - 4.3e-06 26.8 20.6 9.6e-06 25.6 20.6 1.6 1 1 0 1 1 1 1 Fatty acid desaturase UPF0220 PF05255.11 EGG08944.1 - 2.5e-55 186.5 0.1 3e-55 186.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF1751 PF08551.10 EGG08944.1 - 0.069 13.7 0.5 0.11 13.1 0.5 1.4 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Glyco_hydro_15 PF00723.21 EGG08945.1 - 3.9e-69 233.6 0.0 4.5e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Acyltransferase PF01553.21 EGG08946.1 - 7.9e-22 77.3 0.0 1.5e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EGG08946.1 - 3.6e-08 33.4 2.7 1.1e-05 25.4 0.7 2.4 2 0 0 2 2 2 2 Acyltransferase C-terminus LprI PF07007.12 EGG08947.1 - 0.0043 17.7 0.1 0.0043 17.7 0.1 2.7 2 1 0 2 2 2 1 Lysozyme inhibitor LprI Ribosomal_L37ae PF01780.19 EGG08949.1 - 2.6e-41 139.6 11.4 3e-41 139.4 11.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 EGG08949.1 - 0.00038 20.4 1.9 0.0006 19.7 1.9 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-RING_13 PF17977.1 EGG08949.1 - 0.001 19.2 1.7 0.0014 18.7 1.7 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-BED PF02892.15 EGG08949.1 - 0.0069 16.4 3.5 0.44 10.6 0.2 2.2 1 1 1 2 2 2 2 BED zinc finger DUF1451 PF07295.11 EGG08949.1 - 0.051 13.6 0.6 0.071 13.1 0.6 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-H2C2_2 PF13465.6 EGG08949.1 - 0.053 14.0 4.9 2.4 8.8 0.9 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Rsm1 PF08600.10 EGG08949.1 - 0.064 13.4 0.3 0.087 13.0 0.3 1.3 1 0 0 1 1 1 0 Rsm1-like C1_2 PF03107.16 EGG08949.1 - 0.12 12.7 2.6 3.8 7.9 3.3 2.0 1 1 1 2 2 2 0 C1 domain SKN1 PF03935.15 EGG08950.1 - 5.9e-184 612.1 2.8 6.6e-184 612.0 2.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 EGG08950.1 - 0.00026 20.5 0.0 0.00092 18.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Pilin_GH PF16734.5 EGG08950.1 - 0.021 15.1 2.0 0.11 12.9 1.9 2.1 2 0 0 2 2 2 0 Type IV pilin-like G and H, putative ELO PF01151.18 EGG08951.1 - 1.4e-58 198.4 20.0 1.7e-58 198.1 20.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PRO8NT PF08082.11 EGG08954.1 - 4e-30 104.8 5.7 8.9e-20 71.2 0.8 2.7 2 1 1 3 3 3 2 PRO8NT (NUC069), PrP8 N-terminal domain DUF4291 PF14124.6 EGG08959.1 - 0.031 14.1 0.5 0.07 13.0 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4291) DUF4501 PF14946.6 EGG08963.1 - 0.15 12.1 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) UTP25 PF06862.12 EGG08964.1 - 3.6e-135 451.4 2.0 4.7e-135 451.0 2.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EGG08964.1 - 0.0086 15.9 0.1 0.39 10.5 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Shisa PF13908.6 EGG08965.1 - 0.1 12.8 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Img2 PF05046.14 EGG08967.1 - 3.2e-17 62.6 0.0 5.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) RAI16-like PF10257.9 EGG08970.1 - 1.7e-44 152.2 0.0 3.9e-44 151.0 0.0 1.6 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein CorA PF01544.18 EGG08971.1 - 8.8e-08 31.8 2.3 1.5e-07 31.0 2.3 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein EAR PF07897.11 EGG08974.1 - 0.097 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression Exo_endo_phos_2 PF14529.6 EGG08976.1 - 1.3e-12 47.6 0.2 1.8e-12 47.2 0.2 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF559 PF04480.12 EGG08982.1 - 0.09 12.6 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF559) M64_N PF16217.5 EGG08983.1 - 0.11 12.0 0.1 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Peptidase M64 N-terminus Chlorosome_CsmC PF11098.8 EGG08984.1 - 0.24 11.4 0.8 3.3 7.7 0.1 2.6 3 0 0 3 3 3 0 Chlorosome envelope protein C Helitron_like_N PF14214.6 EGG08987.1 - 0.024 14.8 0.1 0.027 14.7 0.1 1.4 1 1 0 1 1 1 0 Helitron helicase-like domain at N-terminus ALG3 PF05208.13 EGG08988.1 - 2.9e-32 112.5 26.1 5.2e-20 72.2 18.5 3.0 1 1 1 2 2 2 2 ALG3 protein PTCB-BRCT PF12738.7 EGG08992.1 - 5.2e-07 29.5 0.0 3.7e-05 23.6 0.0 3.5 4 0 0 4 4 4 1 twin BRCT domain DUF2052 PF09747.9 EGG08995.1 - 0.03 14.5 6.5 0.042 14.0 6.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DNA_pol_phi PF04931.13 EGG08995.1 - 0.038 12.1 4.7 0.043 11.9 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 EGG08995.1 - 0.073 13.3 8.2 0.18 12.0 8.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 EGG08995.1 - 0.08 12.3 6.2 0.12 11.7 6.2 1.2 1 0 0 1 1 1 0 NOA36 protein EBV-NA3 PF05009.12 EGG08995.1 - 0.66 9.5 4.6 1.7 8.1 3.4 1.9 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) TLP-20 PF06088.11 EGG08995.1 - 0.73 9.7 6.4 1.2 9.0 6.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.14 EGG08995.1 - 0.82 7.9 6.9 0.86 7.8 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 EGG08995.1 - 1.3 9.4 15.4 0.42 11.0 12.5 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 EGG08995.1 - 1.7 8.7 10.5 2.1 8.3 9.9 1.6 1 1 0 1 1 1 0 RXT2-like, N-terminal AA_permease_2 PF13520.6 EGG08996.1 - 5.9e-62 209.9 41.6 7.2e-62 209.6 41.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGG08996.1 - 1.4e-22 80.0 38.6 1.9e-22 79.5 38.2 1.3 1 1 0 1 1 1 1 Amino acid permease BUD22 PF09073.10 EGG08997.1 - 1.9e-46 159.3 31.2 1.9e-46 159.3 31.2 3.3 2 1 0 2 2 2 1 BUD22 ICL PF00463.21 EGG09000.1 - 5.3e-173 576.3 0.0 6.2e-173 576.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EGG09000.1 - 4.9e-14 52.4 0.1 8.4e-13 48.3 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF5305 PF17231.2 EGG09001.1 - 0.15 11.4 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) UCH PF00443.29 EGG09003.1 - 1.1e-30 107.0 0.6 2.9e-30 105.6 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGG09003.1 - 3.3e-10 40.1 0.0 6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein SAP PF02037.27 EGG09003.1 - 4.2e-10 39.1 4.0 1.1e-09 37.8 4.0 1.8 1 0 0 1 1 1 1 SAP domain Telomere_Sde2_2 PF13297.6 EGG09003.1 - 0.042 13.5 0.5 0.1 12.2 0.5 1.7 1 0 0 1 1 1 0 Telomere stability C-terminal HeH PF12949.7 EGG09003.1 - 0.19 11.5 1.2 0.49 10.2 1.2 1.8 1 1 0 1 1 1 0 HeH/LEM domain RNA_pol_Rpb2_6 PF00562.28 EGG09004.1 - 1e-127 426.4 0.1 1.5e-127 425.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGG09004.1 - 6.4e-65 218.5 0.0 9.6e-65 217.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EGG09004.1 - 4.5e-49 166.7 0.1 2.2e-48 164.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EGG09004.1 - 1.9e-32 111.5 0.1 4.5e-32 110.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EGG09004.1 - 1.7e-25 88.9 0.1 4e-25 87.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EGG09004.1 - 1.1e-24 86.8 0.7 2.9e-24 85.4 0.7 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 EGG09004.1 - 1.5e-24 86.0 1.3 2.9e-24 85.1 0.6 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 MRNIP PF15749.5 EGG09004.1 - 0.0099 16.6 0.2 0.0099 16.6 0.2 2.1 2 0 0 2 2 2 1 MRN-interacting protein Varsurf_PPLC PF03490.13 EGG09004.1 - 0.053 13.5 0.0 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C HNH_3 PF13392.6 EGG09004.1 - 0.078 12.7 0.3 0.18 11.6 0.3 1.6 1 0 0 1 1 1 0 HNH endonuclease zf-UBP PF02148.19 EGG09005.1 - 0.033 14.5 5.3 0.075 13.4 5.3 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein KDZ PF18758.1 EGG09006.1 - 2.1e-18 66.8 0.0 3.9e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGG09006.1 - 0.003 17.7 0.2 0.02 15.0 0.2 2.1 1 1 1 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases MarB PF13999.6 EGG09007.1 - 0.3 11.0 2.8 1.3 8.9 0.9 2.2 1 1 1 2 2 2 0 MarB protein CdiA_C_tRNase PF18664.1 EGG09009.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain ATG19_autophagy PF12744.7 EGG09009.1 - 0.054 12.7 1.3 0.11 11.7 1.3 1.4 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding Pepsin-I3 PF06394.13 EGG09009.1 - 0.11 12.7 0.2 0.27 11.5 0.2 1.6 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Nop14 PF04147.12 EGG09011.1 - 1.1e-45 156.3 5.5 7e-19 67.6 0.0 3.0 1 1 2 3 3 3 3 Nop14-like family FAD_binding_3 PF01494.19 EGG09012.1 - 1.2e-63 215.5 0.0 1.4e-62 212.0 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGG09012.1 - 1.7e-23 83.5 0.0 2.9e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EGG09012.1 - 0.0044 16.3 0.0 0.0081 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGG09012.1 - 0.0075 15.0 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EGG09012.1 - 0.01 16.1 0.0 0.036 14.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGG09012.1 - 0.03 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EGG09012.1 - 0.087 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family PQ-loop PF04193.14 EGG09013.1 - 7.3e-12 44.9 0.2 1e-11 44.4 0.2 1.2 1 0 0 1 1 1 1 PQ loop repeat DUF2711 PF10924.8 EGG09013.1 - 0.037 13.6 0.1 0.071 12.7 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2711) GPW_gp25 PF04965.14 EGG09014.1 - 0.033 14.0 0.4 0.049 13.4 0.4 1.3 1 0 0 1 1 1 0 Gene 25-like lysozyme TniQ PF06527.11 EGG09014.1 - 0.072 13.8 1.3 0.14 12.8 1.3 1.6 1 1 0 1 1 1 0 TniQ DUF1598 PF07643.11 EGG09014.1 - 0.1 12.8 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) JmjC PF02373.22 EGG09015.1 - 3.1e-10 40.5 0.0 3.5e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase Glyco_hydro_63N PF16923.5 EGG09016.1 - 0.026 14.6 1.1 0.055 13.5 1.1 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 N-terminal domain DUF4510 PF14971.6 EGG09017.1 - 0.085 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) U-box PF04564.15 EGG09019.1 - 1.4 9.1 5.7 31 4.8 0.0 4.2 4 0 0 4 4 4 0 U-box domain Snf7 PF03357.21 EGG09021.1 - 3.6e-18 65.7 8.2 4.4e-18 65.5 8.2 1.1 1 0 0 1 1 1 1 Snf7 YiiD_C PF09500.10 EGG09021.1 - 0.019 14.8 0.1 0.026 14.3 0.1 1.2 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) DUF3381 PF11861.8 EGG09021.1 - 0.56 10.0 7.1 0.83 9.4 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) JmjC PF02373.22 EGG09025.1 - 1e-13 51.7 0.0 1.5e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGG09025.1 - 0.0023 17.7 0.1 0.0028 17.4 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain AHJR-like PF18743.1 EGG09025.1 - 0.063 12.8 0.2 0.11 12.0 0.2 1.5 1 1 0 1 1 1 0 REase_AHJR-like Cupin_2 PF07883.11 EGG09025.1 - 0.11 12.3 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Cupin domain BolA PF01722.18 EGG09026.1 - 2.8e-14 53.1 0.1 3.9e-14 52.7 0.1 1.4 1 1 0 1 1 1 1 BolA-like protein p450 PF00067.22 EGG09027.1 - 2.9e-52 178.0 0.0 3.9e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LRR_8 PF13855.6 EGG09029.1 - 6.7e-28 96.2 26.8 1.2e-10 41.0 1.5 6.1 7 0 0 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 EGG09029.1 - 3.4e-27 94.0 33.5 4.9e-06 26.8 0.7 8.7 5 2 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGG09029.1 - 2.3e-09 37.0 12.0 0.0011 18.5 0.0 5.2 3 2 1 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 EGG09029.1 - 0.018 15.5 19.3 32 5.6 0.6 8.8 7 3 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 EGG09029.1 - 0.21 11.7 22.0 28 5.1 0.1 8.0 9 0 0 9 9 9 0 Leucine Rich repeat CxC1 PF18802.1 EGG09031.1 - 4.3e-23 81.4 1.5 1.4e-21 76.6 1.5 2.2 1 1 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG09031.1 - 2.7e-08 33.9 0.4 5.2e-08 33.0 0.2 1.5 1 1 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG09031.1 - 0.00043 20.1 0.2 0.00067 19.5 0.1 1.4 1 1 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases CAT PF00302.18 EGG09031.1 - 0.14 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase KDZ PF18758.1 EGG09032.1 - 9.7e-07 28.6 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase ALG3 PF05208.13 EGG09036.1 - 3.3e-132 441.3 17.9 4.1e-132 440.9 17.9 1.0 1 0 0 1 1 1 1 ALG3 protein Ribosomal_L18A PF01775.17 EGG09038.1 - 1.3e-08 34.9 0.1 1.6e-08 34.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Glyco_hydro_18 PF00704.28 EGG09040.1 - 2.2e-48 165.6 0.0 2.7e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ETRAMP PF09716.10 EGG09040.1 - 0.078 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF702 PF05142.12 EGG09041.1 - 0.019 15.4 0.1 0.061 13.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF702) CSN7a_helixI PF18392.1 EGG09045.1 - 0.093 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain MRP-S31 PF15433.6 EGG09048.1 - 0.11 12.1 2.4 0.18 11.4 2.4 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Herpes_LMP1 PF05297.11 EGG09049.1 - 0.63 9.2 7.6 0.78 8.9 7.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) TFIIA PF03153.13 EGG09051.1 - 0.17 11.8 19.1 0.2 11.7 19.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ECSIT PF06239.11 EGG09052.1 - 0.023 13.8 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway MCM PF00493.23 EGG09053.1 - 1.5e-97 325.1 0.3 2.4e-97 324.4 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGG09053.1 - 9.1e-34 116.0 0.0 1.7e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGG09053.1 - 8.9e-23 80.5 0.3 2.3e-22 79.2 0.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGG09053.1 - 5.9e-12 46.1 0.3 2e-11 44.4 0.3 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGG09053.1 - 8.3e-08 31.9 0.4 1.7e-06 27.6 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGG09053.1 - 0.0017 18.3 0.0 0.0051 16.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGG09053.1 - 0.0088 15.8 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EGG09053.1 - 0.055 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FAM176 PF14851.6 EGG09053.1 - 2.4 7.8 4.4 4.1 7.1 3.1 2.0 2 0 0 2 2 2 0 FAM176 family LSM PF01423.22 EGG09054.1 - 6.7e-09 35.3 0.0 8.7e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGG09054.1 - 0.018 14.7 0.1 0.044 13.4 0.1 1.7 1 1 1 2 2 2 0 Hfq protein Tmemb_14 PF03647.13 EGG09055.1 - 9.3e-24 84.0 11.7 1.1e-23 83.8 11.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Xpo1 PF08389.12 EGG09056.1 - 1.3e-15 57.7 0.3 1.1e-12 48.2 0.1 3.5 2 1 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EGG09056.1 - 1.9e-05 24.5 0.4 0.0005 19.9 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.22 EGG09056.1 - 0.018 15.2 0.1 0.1 12.9 0.1 2.5 1 0 0 1 1 1 0 HEAT repeat Importin_rep PF18773.1 EGG09056.1 - 0.035 13.8 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 Importin 13 repeat HMG_box PF00505.19 EGG09058.1 - 0.038 14.4 0.2 0.1 13.0 0.2 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box DUF4808 PF16066.5 EGG09060.1 - 0.22 12.1 3.2 0.77 10.3 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4808) Ribosomal_L37ae PF01780.19 EGG09061.1 - 7.4e-34 115.7 7.5 8.1e-34 115.6 7.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 EGG09061.1 - 0.00026 20.9 1.9 0.0004 20.3 1.9 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-RING_13 PF17977.1 EGG09061.1 - 0.00079 19.5 1.9 0.00096 19.2 1.9 1.1 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-BED PF02892.15 EGG09061.1 - 0.0036 17.3 3.4 0.3 11.1 0.2 2.1 1 1 1 2 2 2 2 BED zinc finger zf-H2C2_2 PF13465.6 EGG09061.1 - 0.034 14.6 4.9 1.7 9.2 0.9 2.2 1 1 1 2 2 2 0 Zinc-finger double domain DUF1451 PF07295.11 EGG09061.1 - 0.037 14.1 0.7 0.051 13.6 0.7 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Rsm1 PF08600.10 EGG09061.1 - 0.039 14.1 0.2 0.042 14.0 0.2 1.2 1 0 0 1 1 1 0 Rsm1-like C1_2 PF03107.16 EGG09061.1 - 0.079 13.3 2.7 2.4 8.6 3.4 2.0 1 1 1 2 2 2 0 C1 domain DUF4278 PF14105.6 EGG09064.1 - 1.2 9.7 3.6 4.4 7.8 3.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4278) Methyltransf_16 PF10294.9 EGG09066.1 - 8.3e-20 71.2 0.0 1e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase NAD_binding_8 PF13450.6 EGG09066.1 - 0.089 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SLD5_C PF16922.5 EGG09067.1 - 1.5e-10 41.1 0.0 2.7e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EGG09067.1 - 0.00035 21.0 0.2 0.00067 20.1 0.2 1.5 1 0 0 1 1 1 1 GINS complex protein Alpha-L-AF_C PF06964.12 EGG09072.1 - 1.3e-18 67.6 0.1 9.6e-09 35.6 0.0 2.7 3 0 0 3 3 3 2 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 EGG09072.1 - 0.0048 17.2 0.2 0.0093 16.2 0.2 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain CBM_2 PF00553.19 EGG09072.1 - 0.061 13.6 0.8 0.41 11.0 0.2 2.5 2 0 0 2 2 2 0 Cellulose binding domain PI3K_rbd PF00794.18 EGG09072.1 - 0.084 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain Pkinase PF00069.25 EGG09073.1 - 4.8e-74 249.0 0.2 8.3e-74 248.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG09073.1 - 4.8e-36 124.4 0.7 9.1e-36 123.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG09073.1 - 0.008 15.5 0.0 0.008 15.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGG09073.1 - 0.0093 15.9 3.3 0.096 12.6 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG09073.1 - 0.015 14.3 3.4 0.032 13.2 0.0 2.6 2 1 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGG09073.1 - 0.12 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 G-alpha PF00503.20 EGG09074.1 - 2.4e-104 349.3 0.0 2.8e-104 349.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGG09074.1 - 2.5e-15 56.4 0.9 2.8e-09 36.7 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG09074.1 - 0.00076 18.9 0.3 0.18 11.2 0.1 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGG09074.1 - 0.0037 17.5 0.4 0.52 10.5 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EGG09074.1 - 0.04 13.3 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.29 EGG09075.1 - 1.8e-53 180.5 0.0 2.8e-39 134.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 EGG09075.1 - 7.7e-10 38.4 0.5 2e-07 30.7 0.1 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 EGG09075.1 - 7.5e-09 36.2 0.1 0.0058 17.0 0.1 3.1 2 2 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EGG09075.1 - 2.1e-08 34.5 0.0 1.2e-05 25.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 EGG09075.1 - 4.7e-08 32.7 0.0 1.2e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EGG09075.1 - 5.7e-08 33.1 0.0 0.0012 19.1 0.0 3.8 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGG09075.1 - 9.8e-08 31.6 0.4 0.0027 16.9 0.0 3.0 2 1 1 3 3 3 2 TIP49 P-loop domain RuvB_N PF05496.12 EGG09075.1 - 4.2e-07 29.8 0.0 0.025 14.3 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGG09075.1 - 6.5e-07 29.4 0.0 0.00021 21.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGG09075.1 - 3.1e-06 27.2 0.0 0.022 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGG09075.1 - 1.2e-05 25.5 0.0 0.27 11.4 0.0 2.6 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 EGG09075.1 - 1.9e-05 24.1 0.2 0.005 16.2 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EGG09075.1 - 2e-05 24.6 0.0 3.6 7.4 0.0 4.1 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGG09075.1 - 2.6e-05 24.0 0.0 0.066 12.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGG09075.1 - 0.00013 22.5 0.0 0.19 12.3 0.0 3.2 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGG09075.1 - 0.00017 22.0 0.0 0.12 12.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 EGG09075.1 - 0.0002 21.1 0.2 0.2 11.4 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein Parvo_NS1 PF01057.17 EGG09075.1 - 0.00033 19.8 0.0 0.46 9.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 EGG09075.1 - 0.00033 20.4 0.0 1.3 8.7 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 EGG09075.1 - 0.00035 20.8 0.0 0.35 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGG09075.1 - 0.00055 20.5 0.1 0.094 13.2 0.1 3.1 3 0 0 3 3 3 1 ABC transporter NACHT PF05729.12 EGG09075.1 - 0.00081 19.3 0.0 2.1 8.2 0.0 3.2 4 0 0 4 4 2 2 NACHT domain AAA_11 PF13086.6 EGG09075.1 - 0.0012 18.7 0.0 0.51 10.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 EGG09075.1 - 0.0013 18.1 0.4 0.029 13.7 0.1 2.5 2 1 0 2 2 2 1 KaiC AAA_7 PF12775.7 EGG09075.1 - 0.0015 18.1 0.8 0.049 13.1 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region TsaE PF02367.17 EGG09075.1 - 0.0015 18.5 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EGG09075.1 - 0.003 17.4 0.0 0.34 10.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 EGG09075.1 - 0.0078 16.5 0.1 0.072 13.4 0.0 2.1 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_30 PF13604.6 EGG09075.1 - 0.0095 15.7 0.0 0.5 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 EGG09075.1 - 0.01 15.3 0.0 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NB-ARC PF00931.22 EGG09075.1 - 0.012 14.9 0.0 4.9 6.3 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 EGG09075.1 - 0.014 15.0 0.3 3.2 7.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain CPT PF07931.12 EGG09075.1 - 0.024 14.5 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein IPT PF01745.16 EGG09075.1 - 0.027 13.9 0.1 0.75 9.1 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase PhoH PF02562.16 EGG09075.1 - 0.035 13.6 0.0 2.6 7.5 0.0 2.6 3 0 0 3 3 2 0 PhoH-like protein AAA_17 PF13207.6 EGG09075.1 - 0.043 14.2 0.0 13 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EGG09075.1 - 0.048 12.7 0.0 10 5.1 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 EGG09075.1 - 0.052 13.9 0.3 0.79 10.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EGG09075.1 - 0.26 10.5 0.1 7.7 5.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) adh_short PF00106.25 EGG09078.1 - 2.3e-30 105.5 0.0 2.6e-24 85.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG09078.1 - 7.3e-17 61.7 0.0 7.6e-16 58.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG09078.1 - 0.00012 22.1 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Trimer_CC PF08954.11 EGG09078.1 - 0.0066 16.0 0.4 3.8 7.2 0.1 2.4 2 0 0 2 2 2 2 Trimerisation motif Epimerase PF01370.21 EGG09078.1 - 0.043 13.3 0.0 0.061 12.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Galanin PF01296.18 EGG09079.1 - 0.044 13.8 0.3 0.085 12.9 0.3 1.4 1 0 0 1 1 1 0 Galanin C2 PF00168.30 EGG09082.1 - 9.7e-17 61.2 0.2 1.9e-13 50.6 0.0 2.8 2 0 0 2 2 2 2 C2 domain Tam41_Mmp37 PF09139.11 EGG09083.1 - 1.3e-118 396.2 0.0 3.4e-118 394.8 0.0 1.6 2 0 0 2 2 2 1 Phosphatidate cytidylyltransferase, mitochondrial Sec61_beta PF03911.16 EGG09084.1 - 1.1e-14 54.1 0.0 1.3e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Sec61beta family RabGAP-TBC PF00566.18 EGG09085.1 - 5.1e-43 147.2 0.6 5.1e-43 147.2 0.6 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EGG09085.1 - 3.3e-06 26.6 3.5 0.0015 18.3 0.1 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGG09085.1 - 0.00012 21.3 1.2 0.039 13.5 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGG09085.1 - 0.00036 20.9 4.0 0.037 14.5 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair RNase_T PF00929.24 EGG09085.1 - 0.027 15.0 0.8 10 6.6 0.2 3.7 4 0 0 4 4 4 0 Exonuclease Pkinase PF00069.25 EGG09090.1 - 1.3e-15 57.5 0.0 1.4e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG09090.1 - 1.5e-05 24.4 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Adeno_E3B PF03376.14 EGG09090.1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 Adenovirus E3B protein Kinase-like PF14531.6 EGG09090.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.3 1 1 0 1 1 1 0 Kinase-like Asn_synthase PF00733.21 EGG09092.1 - 4.8e-91 306.1 0.2 2.5e-53 182.0 0.0 2.4 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EGG09092.1 - 1.7e-35 121.6 0.0 4.1e-35 120.4 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGG09092.1 - 3.9e-29 101.5 0.0 7.9e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGG09092.1 - 1.6e-05 24.5 0.0 3.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EGG09092.1 - 0.0026 16.9 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD synthase QueC PF06508.13 EGG09092.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC MutL PF13941.6 EGG09094.1 - 0.013 14.1 0.1 0.022 13.4 0.1 1.2 1 0 0 1 1 1 0 MutL protein Dcc1 PF09724.9 EGG09095.1 - 7.4e-68 229.3 6.1 9e-68 229.0 6.1 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 DUF5099 PF17025.5 EGG09095.1 - 0.27 11.7 2.4 0.45 11.0 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5099) Asp PF00026.23 EGG09096.1 - 8.1e-22 78.0 0.1 4.8e-20 72.2 0.1 2.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG09096.1 - 8.7e-09 35.9 0.0 0.00043 20.6 0.0 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Zn_clus PF00172.18 EGG09097.1 - 0.0035 17.4 4.9 0.0035 17.4 4.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_CH_N PF12471.8 EGG09099.1 - 2.1e-89 298.4 0.0 3e-89 297.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EGG09099.1 - 1.7e-14 53.7 0.0 2.7e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF4748 PF15932.5 EGG09101.1 - 5.3e-12 45.3 0.1 1.1e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) Gram_pos_anchor PF00746.21 EGG09101.1 - 0.048 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif 4HBT_3 PF13622.6 EGG09102.1 - 1e-24 88.1 1.2 1.4e-24 87.7 1.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Metallophos PF00149.28 EGG09107.1 - 1.9e-10 41.6 0.0 5.4e-10 40.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG09107.1 - 1.4e-07 31.9 0.1 0.0012 19.0 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Apc13p PF05839.11 EGG09108.1 - 0.036 14.2 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Apc13p protein DUF982 PF06169.12 EGG09108.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF982) Glyco_trans_2_3 PF13632.6 EGG09109.1 - 1.9e-27 96.5 4.4 1.9e-27 96.5 4.4 3.8 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Acyl_transf_3 PF01757.22 EGG09109.1 - 1.9e-17 63.4 38.2 1.9e-17 63.4 38.2 3.1 3 0 0 3 3 3 1 Acyltransferase family Glyco_tranf_2_3 PF13641.6 EGG09109.1 - 1.9e-14 54.1 0.0 3.1e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PX PF00787.24 EGG09110.1 - 7.7e-22 77.4 0.1 2e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EGG09110.1 - 1.7e-06 27.8 2.9 0.01 15.4 0.4 2.3 2 0 0 2 2 2 2 Vps5 C terminal like Abhydrolase_1 PF00561.20 EGG09111.1 - 1e-23 84.3 0.0 6.3e-22 78.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG09111.1 - 7.7e-14 52.8 0.0 1.1e-13 52.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG09111.1 - 1.1e-12 47.7 0.0 1.5e-12 47.3 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGG09111.1 - 6.2e-11 42.4 0.4 2.1e-09 37.4 0.4 2.2 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 EGG09111.1 - 1.4e-07 31.8 0.0 1.8e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Palm_thioest PF02089.15 EGG09111.1 - 2.2e-05 24.4 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EGG09111.1 - 2.2e-05 24.1 0.0 4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 EGG09111.1 - 0.00018 20.9 0.6 0.092 12.1 0.2 2.9 2 1 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.7 EGG09111.1 - 0.0004 19.4 0.0 0.00064 18.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EGG09111.1 - 0.00066 18.8 0.0 0.00098 18.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Lipase_2 PF01674.18 EGG09111.1 - 0.0013 18.3 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 2) Ndr PF03096.14 EGG09111.1 - 0.0017 17.1 0.0 0.0025 16.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 EGG09111.1 - 0.012 15.3 0.0 0.03 14.1 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EGG09111.1 - 0.02 14.7 0.1 0.076 12.9 0.0 1.9 1 1 1 2 2 2 0 Lipase (class 3) PAF-AH_p_II PF03403.13 EGG09111.1 - 0.021 13.4 0.5 0.33 9.4 0.0 2.4 2 1 1 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II DUF900 PF05990.12 EGG09111.1 - 0.028 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 EGG09111.1 - 0.048 12.8 0.1 0.12 11.5 0.0 1.5 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2048 PF09752.9 EGG09111.1 - 0.05 12.7 0.0 0.092 11.8 0.0 1.6 1 1 0 1 1 1 0 Abhydrolase domain containing 18 Esterase PF00756.20 EGG09111.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Ser_hydrolase PF06821.13 EGG09111.1 - 0.073 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_3 PF07859.13 EGG09111.1 - 0.16 11.8 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 EGG09111.1 - 0.27 10.9 3.2 3.3 7.3 0.8 3.4 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Asp PF00026.23 EGG09113.1 - 2.5e-62 211.1 0.1 2.9e-62 210.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG09113.1 - 1.8e-08 34.8 1.5 1.6e-07 31.8 1.5 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGG09113.1 - 0.007 17.0 0.2 1.9 9.2 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease Asp PF00026.23 EGG09114.1 - 6.7e-62 209.7 0.0 7.8e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG09114.1 - 9.2e-10 39.0 0.3 2.1e-08 34.6 0.3 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGG09114.1 - 0.00039 21.0 0.3 0.1 13.3 0.1 2.9 2 1 0 2 2 2 2 Aspartyl protease CNH PF00780.22 EGG09115.1 - 2.9e-56 191.1 0.0 4.6e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EGG09115.1 - 2.2e-25 90.0 0.5 3.4e-25 89.3 0.5 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EGG09115.1 - 4.1e-17 62.6 0.0 8.3e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 EGG09115.1 - 0.00068 19.6 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Period_C PF12114.8 EGG09115.1 - 0.0084 15.7 1.6 0.0084 15.7 1.6 2.1 2 0 0 2 2 2 1 Period protein 2/3C-terminal region EamA PF00892.20 EGG09116.1 - 2.2e-05 24.6 10.8 2.2e-05 24.6 10.8 2.4 3 0 0 3 3 3 2 EamA-like transporter family BTG PF07742.12 EGG09118.1 - 0.036 13.9 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 BTG family zf-MYND PF01753.18 EGG09121.1 - 2.1e-08 34.1 8.7 4.5e-08 33.1 8.6 1.7 1 1 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGG09121.1 - 0.00013 22.2 11.4 0.00027 21.2 11.4 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding UPF0242 PF06785.11 EGG09122.1 - 0.56 10.3 15.4 0.72 9.9 15.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_S46 PF10459.9 EGG09122.1 - 6.5 5.3 16.7 7.4 5.1 16.7 1.1 1 0 0 1 1 1 0 Peptidase S46 Peptidase_M16 PF00675.20 EGG09124.1 - 7e-06 26.1 0.0 7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF3435 PF11917.8 EGG09125.1 - 1.1e-06 27.9 0.0 2e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) ECSIT_C PF14784.6 EGG09126.1 - 0.0074 16.6 0.0 0.0078 16.6 0.0 1.2 1 0 0 1 1 1 1 C-terminal domain of the ECSIT protein SHR3_chaperone PF08229.11 EGG09127.1 - 6.9e-28 96.9 3.1 2.4e-27 95.1 3.1 1.7 1 1 0 1 1 1 1 ER membrane protein SH3 CPP1-like PF11833.8 EGG09127.1 - 0.083 12.5 4.1 2 8.0 0.2 2.6 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TPR_16 PF13432.6 EGG09127.1 - 0.12 13.1 0.1 0.38 11.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Rot1 PF10681.9 EGG09128.1 - 1.1e-64 217.8 0.3 1.4e-64 217.5 0.3 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal SF3b10 PF07189.11 EGG09129.1 - 1e-35 121.7 0.0 1.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF4648 PF15505.6 EGG09130.1 - 0.04 14.8 0.1 1.1 10.2 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4648) AIP3 PF03915.13 EGG09131.1 - 1.5e-136 455.8 1.7 2.1e-136 455.3 1.7 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 AAA_13 PF13166.6 EGG09131.1 - 0.0032 16.2 3.0 0.0071 15.1 3.0 1.6 1 0 0 1 1 1 1 AAA domain Lectin_N PF03954.14 EGG09131.1 - 0.039 13.7 8.8 0.02 14.7 2.6 3.5 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain NB-LRR PF12061.8 EGG09131.1 - 0.05 12.9 0.8 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Late blight resistance protein R1 KdpD PF02702.17 EGG09131.1 - 0.053 13.0 0.9 0.13 11.7 0.9 1.6 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain DUF1664 PF07889.12 EGG09131.1 - 0.079 13.0 13.6 4.1 7.5 5.2 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) EzrA PF06160.12 EGG09131.1 - 0.08 11.1 8.7 1.9 6.6 0.0 3.0 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA FapA PF03961.13 EGG09131.1 - 0.084 11.5 4.4 0.17 10.5 2.5 2.2 2 1 0 2 2 2 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 EGG09131.1 - 0.15 12.1 15.4 9.4 6.3 0.1 3.8 3 1 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EGG09131.1 - 0.21 12.1 13.1 4.4 7.8 0.1 4.1 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 EGG09131.1 - 0.27 11.8 12.5 9.4 6.9 0.1 4.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Syntaxin PF00804.25 EGG09131.1 - 0.5 10.0 10.1 1.4 8.6 2.0 3.2 2 1 1 3 3 3 0 Syntaxin Prefoldin PF02996.17 EGG09131.1 - 0.51 10.3 6.9 8.2 6.4 0.0 4.1 4 1 1 5 5 3 0 Prefoldin subunit Med9 PF07544.13 EGG09131.1 - 0.78 9.9 12.4 42 4.3 0.0 5.0 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.11 EGG09131.1 - 0.81 10.0 12.6 1.9 8.8 1.0 4.7 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Zw10 PF06248.13 EGG09131.1 - 0.91 8.0 6.6 0.17 10.5 2.7 1.7 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 ApoO PF09769.9 EGG09131.1 - 0.93 9.5 5.7 13 5.8 0.2 3.4 3 1 1 4 4 4 0 Apolipoprotein O Fib_alpha PF08702.10 EGG09131.1 - 1.3 9.2 12.5 0.24 11.6 2.4 3.5 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Allexi_40kDa PF05549.11 EGG09131.1 - 2.1 7.8 8.2 3 7.3 1.5 3.0 1 1 1 3 3 3 0 Allexivirus 40kDa protein DUF1515 PF07439.11 EGG09131.1 - 2.2 8.3 6.2 3.7 7.6 1.6 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1515) CHDCT2 PF08074.11 EGG09131.1 - 2.3 8.4 8.0 3.1 7.9 0.4 3.3 1 1 1 3 3 3 0 CHDCT2 (NUC038) domain FlaC_arch PF05377.11 EGG09131.1 - 2.6 8.5 10.6 19 5.8 0.5 4.9 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF4618 PF15397.6 EGG09131.1 - 3.7 6.9 12.3 1.2 8.5 3.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) TMPIT PF07851.13 EGG09131.1 - 5 6.3 6.2 7.6 5.7 1.4 2.8 2 1 1 3 3 3 0 TMPIT-like protein DUF848 PF05852.11 EGG09131.1 - 7.9 6.6 9.7 9.4 6.3 4.4 3.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) RasGAP_C PF03836.15 EGG09131.1 - 9.7 6.3 9.4 25 5.0 0.1 3.9 3 1 1 4 4 4 0 RasGAP C-terminus DHR10 PF18595.1 EGG09131.1 - 9.9 6.3 16.3 9.9 6.3 0.2 4.6 5 0 0 5 5 5 0 Designed helical repeat protein 10 domain zf-CCHC_3 PF13917.6 EGG09133.1 - 0.066 13.2 21.2 0.28 11.2 7.3 2.5 1 1 1 2 2 2 0 Zinc knuckle Yae1_N PF09811.9 EGG09134.1 - 0.025 14.3 0.3 0.049 13.3 0.3 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal PRP1_N PF06424.12 EGG09136.1 - 9.7e-47 159.1 0.6 9.7e-47 159.1 0.6 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EGG09136.1 - 3.7e-27 92.7 7.7 0.001 19.7 0.1 13.3 5 3 9 14 14 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 EGG09136.1 - 1.8e-20 73.2 4.3 3.1e-06 27.6 0.1 9.1 7 3 3 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG09136.1 - 3.9e-08 33.8 0.8 0.73 10.5 0.0 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 EGG09136.1 - 7.5e-08 31.9 7.3 0.014 14.6 0.2 6.2 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG09136.1 - 3.1e-07 30.0 3.1 31 5.0 0.0 9.8 13 0 0 13 13 12 0 Tetratricopeptide repeat NARP1 PF12569.8 EGG09136.1 - 0.00015 20.9 3.8 0.077 11.9 0.0 4.3 2 1 3 5 5 5 2 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 EGG09136.1 - 0.0011 19.1 0.0 4.4 7.5 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Suf PF05843.14 EGG09136.1 - 0.0032 17.5 0.2 25 4.7 0.0 4.5 3 2 0 4 4 4 0 Suppressor of forked protein (Suf) DUF3808 PF10300.9 EGG09136.1 - 0.044 12.5 0.2 8.1 5.1 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3808) Wzy_C_2 PF11846.8 EGG09136.1 - 0.045 13.7 2.9 33 4.3 0.0 5.5 4 2 3 7 7 7 0 Virulence factor membrane-bound polymerase, C-terminal Babuvirus_MP PF07234.11 EGG09136.1 - 0.24 11.6 0.3 6.6 6.9 0.0 3.4 4 1 1 5 5 4 0 Movement and RNA silencing protein NUDIX PF00293.28 EGG09137.1 - 3.8e-08 33.5 0.2 4.6e-08 33.2 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain DUF4031 PF13223.6 EGG09137.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) F-actin_cap_A PF01267.17 EGG09139.1 - 3.5e-90 302.1 1.5 4.1e-90 301.8 1.5 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF2278 PF10042.9 EGG09139.1 - 0.055 13.5 0.1 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2278) FAR1 PF03101.15 EGG09140.1 - 2.1e-07 31.5 0.0 2.1e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.11 EGG09140.1 - 0.00077 19.8 0.2 0.00077 19.8 0.2 1.9 2 1 0 2 2 2 1 Transcription factor AFT MutS_IV PF05190.18 EGG09140.1 - 0.024 15.0 0.0 0.06 13.7 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV Sad1_UNC PF07738.13 EGG09144.1 - 2.6e-27 95.4 0.0 4.2e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DAGK_cat PF00781.24 EGG09146.1 - 1.1e-12 47.7 0.0 2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Thr_synth_N PF14821.6 EGG09147.1 - 3.5e-27 94.4 0.0 4.6e-26 90.8 0.0 2.7 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 EGG09147.1 - 8.1e-13 48.4 0.0 1.5e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ZapA PF05164.13 EGG09147.1 - 0.058 13.8 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 Cell division protein ZapA TFIIS_M PF07500.14 EGG09148.1 - 3e-20 72.8 2.9 5.1e-20 72.0 2.9 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 EGG09148.1 - 9.8e-12 45.0 0.0 2.3e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 EGG09148.1 - 0.0014 18.5 9.9 0.24 11.3 4.5 2.5 2 0 0 2 2 2 2 PHD-finger Glyco_hydro_5_C PF18564.1 EGG09150.1 - 4.5e-13 49.6 0.0 7.2e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain UFC1 PF08694.11 EGG09150.1 - 0.039 13.6 0.7 0.1 12.2 0.7 1.7 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 zf-CCHC_3 PF13917.6 EGG09152.1 - 0.00039 20.3 0.2 0.00067 19.6 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGG09152.1 - 0.11 12.4 2.0 0.37 10.7 2.0 1.9 1 0 0 1 1 1 0 Zinc knuckle CLIP1_ZNF PF16641.5 EGG09152.1 - 0.12 12.3 0.3 0.12 12.3 0.3 1.5 2 0 0 2 2 2 0 CLIP1 zinc knuckle JHD PF17811.1 EGG09153.1 - 0.15 12.6 0.4 40 4.8 0.0 3.0 2 1 1 3 3 3 0 Jumonji helical domain Sad1_UNC PF07738.13 EGG09154.1 - 2.1e-29 102.2 0.0 3.6e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal NPV_P10 PF05531.12 EGG09154.1 - 0.04 14.4 1.7 1.4 9.4 0.1 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EGG09154.1 - 0.17 12.2 2.3 0.48 10.8 2.2 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2828 PF11443.8 EGG09155.1 - 0.04 12.0 3.9 0.046 11.8 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1754 PF08555.10 EGG09155.1 - 0.12 13.2 10.3 0.2 12.5 10.3 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Lin-8 PF03353.15 EGG09155.1 - 0.29 10.7 12.7 0.37 10.3 12.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FAM176 PF14851.6 EGG09155.1 - 0.29 10.8 6.9 0.52 10.0 6.9 1.3 1 0 0 1 1 1 0 FAM176 family Roughex PF06020.11 EGG09155.1 - 0.34 10.0 6.2 0.56 9.2 6.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein EELM2 PF15863.5 EGG09155.1 - 0.53 10.4 5.4 2.2 8.4 5.4 1.9 1 1 0 1 1 1 0 Extended EGL-27 and MTA1 homology domain FAM76 PF16046.5 EGG09155.1 - 0.74 9.1 9.3 1 8.7 9.3 1.2 1 0 0 1 1 1 0 FAM76 protein SprA-related PF12118.8 EGG09155.1 - 1 8.4 12.0 1.9 7.5 12.0 1.3 1 0 0 1 1 1 0 SprA-related family AIF_C PF14721.6 EGG09155.1 - 2 8.8 5.8 5 7.5 5.8 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TERB2 PF15101.6 EGG09155.1 - 2.1 8.3 10.0 3.4 7.7 10.0 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 EGG09155.1 - 2.3 6.9 8.9 2.8 6.6 8.9 1.1 1 0 0 1 1 1 0 Presenilin SMN PF06003.12 EGG09155.1 - 6.2 6.0 7.8 9.7 5.4 7.8 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Pex14_N PF04695.13 EGG09155.1 - 9.1 6.9 12.6 16 6.1 12.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Topoisom_bac PF01131.20 EGG09158.1 - 7.8e-108 361.1 0.0 9.5e-108 360.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EGG09158.1 - 8.4e-18 64.5 0.0 2.1e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Orbi_VP6 PF01516.16 EGG09158.1 - 3.5 7.1 16.1 6.5 6.2 16.1 1.4 1 0 0 1 1 1 0 Orbivirus helicase VP6 zf-CCHC PF00098.23 EGG09159.1 - 1e-14 53.8 18.7 4.2e-07 29.7 1.1 3.2 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 EGG09159.1 - 3.2e-05 23.6 6.8 0.00021 21.0 0.5 3.0 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.6 EGG09159.1 - 0.00039 20.3 16.0 0.0032 17.4 2.0 3.0 2 1 1 3 3 3 2 Zinc knuckle Copper-fist PF00649.18 EGG09159.1 - 0.019 14.4 2.8 0.58 9.7 0.2 2.3 1 1 1 2 2 2 0 Copper fist DNA binding domain zf-CCHC_5 PF14787.6 EGG09159.1 - 0.078 12.7 0.3 0.078 12.7 0.3 2.6 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 EGG09159.1 - 0.31 11.4 9.1 0.35 11.2 0.9 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.6 EGG09159.1 - 2.3 8.0 12.3 2.5 7.9 0.6 2.9 3 0 0 3 3 3 0 Zinc knuckle PHD PF00628.29 EGG09159.1 - 2.6 8.0 11.4 0.11 12.4 4.7 2.0 2 1 0 2 2 2 0 PHD-finger zinc_ribbon_10 PF10058.9 EGG09159.1 - 3.3 7.5 11.4 0.31 10.8 1.6 2.9 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Thi4 PF01946.17 EGG09161.1 - 0.13 11.5 0.1 0.17 11.1 0.1 1.1 1 0 0 1 1 1 0 Thi4 family HK PF02110.15 EGG09163.1 - 5.1e-08 32.6 1.9 1.6e-07 30.9 1.9 1.7 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family dCache_1 PF02743.18 EGG09165.1 - 0.11 12.3 0.0 0.36 10.6 0.1 1.7 1 1 1 2 2 2 0 Cache domain WD40 PF00400.32 EGG09167.1 - 1.8e-57 189.9 31.4 3.2e-10 40.4 0.3 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG09167.1 - 2.7e-22 78.9 1.0 0.00052 20.3 0.0 6.1 2 2 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG09167.1 - 2e-07 30.1 2.3 0.099 11.3 0.1 5.4 4 2 2 6 6 6 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGG09167.1 - 1e-05 24.7 0.0 0.36 9.7 0.0 3.7 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGG09167.1 - 4.2e-05 23.5 0.0 0.0011 18.9 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 EGG09167.1 - 0.0023 16.7 1.9 0.14 10.9 0.2 3.2 1 1 2 3 3 3 1 Nup133 N terminal like NLE PF08154.12 EGG09167.1 - 0.0073 16.8 0.1 0.015 15.8 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nbas_N PF15492.6 EGG09167.1 - 0.011 15.1 0.1 2.6 7.3 0.0 3.1 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 EGG09167.1 - 0.011 14.1 0.0 0.13 10.6 0.0 2.3 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 EGG09167.1 - 0.05 12.9 0.0 4.5 6.5 0.0 3.0 3 0 0 3 3 3 0 WD40-like domain PD40 PF07676.12 EGG09167.1 - 0.05 13.6 0.0 2.2 8.3 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Asp PF00026.23 EGG09168.1 - 4.7e-67 226.7 0.7 5.8e-67 226.3 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG09168.1 - 2.1e-11 44.4 3.5 6.3e-09 36.3 2.8 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DUF5034 PF16437.5 EGG09170.1 - 0.1 12.6 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5034) Polysacc_deac_1 PF01522.21 EGG09172.1 - 4e-25 88.1 0.0 7e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Barttin PF15462.6 EGG09173.1 - 0.19 11.5 4.9 0.34 10.6 4.9 1.5 1 1 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Proteasome PF00227.26 EGG09174.1 - 2.7e-35 121.6 0.0 3.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit BPS PF08947.10 EGG09176.1 - 0.042 13.7 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 BPS (Between PH and SH2) zf-C2H2 PF00096.26 EGG09177.1 - 0.00014 22.2 9.7 0.016 15.6 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG09177.1 - 0.0028 18.0 7.4 0.0028 18.0 7.4 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG09177.1 - 0.1 13.5 13.3 0.96 10.5 1.8 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Actin_micro PF17003.5 EGG09177.1 - 0.15 11.3 0.9 0.2 10.8 0.9 1.1 1 0 0 1 1 1 0 Putative actin-like family Ribosomal_L16 PF00252.18 EGG09178.1 - 2.3e-38 131.2 0.0 2.6e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Sdh_cyt PF01127.22 EGG09179.1 - 1.2e-21 76.9 0.3 1.9e-21 76.3 0.3 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sec23_trunk PF04811.15 EGG09179.1 - 0.046 13.3 0.0 0.17 11.4 0.0 1.8 1 1 1 2 2 2 0 Sec23/Sec24 trunk domain zf-C2H2 PF00096.26 EGG09180.1 - 3e-10 40.0 10.5 0.01 16.3 0.4 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG09180.1 - 5.2e-09 36.1 11.4 6.6e-05 23.2 0.4 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG09180.1 - 3.7e-06 27.3 10.7 0.052 14.4 0.4 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGG09180.1 - 0.00076 19.4 8.5 0.048 13.7 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-UBP_var PF17807.1 EGG09180.1 - 0.0043 16.8 0.5 0.71 9.7 0.0 3.3 3 0 0 3 3 3 1 Variant UBP zinc finger zf-C2H2_jaz PF12171.8 EGG09180.1 - 0.011 16.0 1.2 0.025 14.9 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CTP_transf_1 PF01148.20 EGG09181.1 - 0.12 12.1 4.8 0.24 11.1 4.7 1.5 1 1 0 1 1 1 0 Cytidylyltransferase family PH_4 PF15404.6 EGG09183.1 - 2.1e-12 47.2 0.4 2.1e-12 47.2 0.4 2.4 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EGG09183.1 - 0.032 14.7 10.2 11 6.6 0.1 5.0 5 0 0 5 5 5 0 PH domain RhoGEF PF00621.20 EGG09184.1 - 3.1e-20 73.2 5.5 3.1e-20 73.2 5.5 2.0 2 0 0 2 2 2 1 RhoGEF domain TGF_beta_GS PF08515.12 EGG09184.1 - 0.067 12.7 0.1 0.19 11.2 0.1 1.8 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif UPF0183 PF03676.14 EGG09185.1 - 2.6e-57 194.9 0.0 4.7e-57 194.1 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) Alpha_kinase PF02816.18 EGG09186.1 - 6.4e-11 42.7 1.8 9.2e-11 42.2 1.8 1.2 1 0 0 1 1 1 1 Alpha-kinase family Glucosamine_iso PF01182.20 EGG09189.1 - 1.1e-63 215.2 0.0 1.4e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glucosamine_iso PF01182.20 EGG09190.1 - 6.2e-48 163.6 0.0 7.4e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ribosomal_L6 PF00347.23 EGG09192.1 - 7.5e-16 58.6 0.0 1.6e-09 38.3 0.0 3.2 3 0 0 3 3 3 3 Ribosomal protein L6 Hydrolase PF00702.26 EGG09193.1 - 0.0067 16.7 0.0 0.0085 16.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGG09193.1 - 0.02 15.0 0.0 0.039 14.0 0.0 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FAT PF02259.23 EGG09194.1 - 1.3e-57 195.6 11.8 1.3e-57 195.6 11.8 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EGG09194.1 - 9.4e-22 78.0 0.0 2.2e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EGG09194.1 - 2.1e-05 24.2 0.3 8.1e-05 22.4 0.3 2.2 1 0 0 1 1 1 1 FATC domain TPR_8 PF13181.6 EGG09194.1 - 0.057 13.6 1.3 4.3 7.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG09194.1 - 0.22 11.7 1.9 14 6.1 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG09194.1 - 2.5 8.4 6.6 4.6 7.6 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TP6A_N PF04406.14 EGG09195.1 - 1.2e-21 76.4 1.0 1.2e-21 76.4 1.0 2.2 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 EGG09195.1 - 0.063 13.2 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) DUF4218 PF13960.6 EGG09196.1 - 0.0057 16.3 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Pox_Ag35 PF03286.14 EGG09197.1 - 0.81 9.4 7.5 1.5 8.6 7.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Asp PF00026.23 EGG09199.1 - 2.8e-108 362.1 0.0 3.4e-108 361.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG09199.1 - 2.7e-14 53.8 0.8 1.3e-12 48.3 0.4 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGG09199.1 - 6.6e-06 26.0 0.0 2.8e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGG09199.1 - 0.00081 19.9 0.0 0.49 11.0 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGG09199.1 - 0.0042 17.7 0.0 1.9 9.2 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease LAP1C PF05609.12 EGG09204.1 - 0.085 11.9 0.0 0.096 11.8 0.0 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Tryp_alpha_amyl PF00234.22 EGG09205.1 - 0.16 12.4 3.4 0.27 11.7 0.3 2.1 1 1 1 2 2 2 0 Protease inhibitor/seed storage/LTP family RuvA_C PF07499.13 EGG09207.1 - 0.16 12.4 0.4 0.39 11.2 0.4 1.7 1 0 0 1 1 1 0 RuvA, C-terminal domain AF-4 PF05110.13 EGG09210.1 - 0.16 10.1 25.8 0.25 9.4 25.8 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein LAP1C PF05609.12 EGG09210.1 - 3.2 6.8 15.6 4.5 6.2 15.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4404 PF14357.6 EGG09210.1 - 4.1 8.1 5.5 5.6 7.7 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) PI3K_1B_p101 PF10486.9 EGG09210.1 - 5.6 4.6 22.0 7.4 4.2 22.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Gpr1_Fun34_YaaH PF01184.19 EGG09211.1 - 7.9e-88 293.5 15.8 9.3e-88 293.2 15.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family zf-DBF PF07535.12 EGG09211.1 - 0.098 12.8 0.7 0.16 12.1 0.7 1.2 1 0 0 1 1 1 0 DBF zinc finger Tr-sialidase_C PF11052.8 EGG09211.1 - 1.1 9.4 8.2 0.56 10.4 1.1 2.6 2 0 0 2 2 2 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal tRNA-synt_2 PF00152.20 EGG09213.1 - 1.7e-74 250.7 0.0 2.2e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGG09213.1 - 2.3e-10 40.3 0.0 7e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGG09213.1 - 1.1e-07 31.6 0.0 0.00036 20.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ribonucleas_3_3 PF14622.6 EGG09214.1 - 1.4e-13 51.1 0.0 2.7e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGG09214.1 - 0.014 16.0 0.0 0.063 13.9 0.0 2.1 1 1 0 1 1 1 0 Ribonuclease III domain CAP59_mtransfer PF11735.8 EGG09216.1 - 1.4e-32 113.3 0.0 2.5e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF4045 PF13254.6 EGG09216.1 - 0.071 12.7 20.3 0.11 12.1 20.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.14 EGG09216.1 - 5.7 5.1 15.2 8.9 4.5 15.2 1.2 1 0 0 1 1 1 0 CDC45-like protein AT_hook PF02178.19 EGG09217.1 - 0.00025 20.5 12.1 0.0028 17.4 2.0 2.6 2 0 0 2 2 2 2 AT hook motif RFX5_DNA_bdg PF14621.6 EGG09217.1 - 0.33 10.7 10.6 8.6 6.1 10.6 2.1 1 1 0 1 1 1 0 RFX5 DNA-binding domain DUF4734 PF15881.5 EGG09218.1 - 0.35 11.0 2.8 0.41 10.8 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4734) NS3 PF17530.2 EGG09219.1 - 0.01 15.4 1.6 0.15 11.6 0.3 2.4 2 0 0 2 2 2 0 Non-structural protein NS3 NUDIX PF00293.28 EGG09220.1 - 2.6e-06 27.5 0.0 8.7e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain YtxC PF08812.11 EGG09220.1 - 0.025 14.2 0.1 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 YtxC-like family Glyco_transf_25 PF01755.17 EGG09221.1 - 2.4e-15 57.0 0.4 2.9e-14 53.4 0.4 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) ATP-synt_8 PF00895.20 EGG09221.1 - 6.4 7.3 7.4 9.4 6.8 6.3 1.8 1 1 0 1 1 1 0 ATP synthase protein 8 RGS PF00615.19 EGG09224.1 - 6e-05 23.3 0.1 0.11 12.8 0.1 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain CRPA PF05745.11 EGG09224.1 - 0.68 9.9 3.2 2.1 8.4 0.1 2.3 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) RGCC PF15151.6 EGG09226.1 - 0.86 9.8 3.2 67 3.7 4.4 2.3 2 0 0 2 2 2 0 Response gene to complement 32 protein family DUF1106 PF06523.11 EGG09229.1 - 0.015 15.4 1.6 0.19 11.8 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1106) DUF4218 PF13960.6 EGG09229.1 - 0.094 12.3 0.0 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) GILT PF03227.16 EGG09233.1 - 1.1e-16 61.0 0.4 2.1e-16 60.0 0.4 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) PCI PF01399.27 EGG09234.1 - 1e-11 45.3 0.9 3.9e-11 43.4 0.0 2.5 3 1 0 3 3 3 1 PCI domain RPN7 PF10602.9 EGG09234.1 - 1.9e-07 31.0 1.7 1.1e-06 28.5 0.6 2.6 2 1 1 3 3 3 1 26S proteasome subunit RPN7 ComR_TPR PF18710.1 EGG09234.1 - 0.0021 17.7 4.6 0.014 14.9 0.1 2.9 2 1 1 3 3 3 1 ComR tetratricopeptide Antirestrict PF03230.13 EGG09234.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Antirestriction protein TPR_14 PF13428.6 EGG09234.1 - 0.23 12.4 1.6 1.3e+02 3.8 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PIN_12 PF16289.5 EGG09234.1 - 0.28 11.7 5.7 0.071 13.6 1.1 2.1 1 1 1 2 2 2 0 PIN domain Ilm1 PF10311.9 EGG09237.1 - 0.042 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF3246 PF11596.8 EGG09238.1 - 0.021 14.3 0.1 0.021 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Lipase_GDSL_3 PF14606.6 EGG09240.1 - 0.25 11.5 1.5 0.43 10.7 1.5 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family TMA7 PF09072.10 EGG09240.1 - 0.26 12.2 0.3 0.26 12.2 0.3 3.1 3 0 0 3 3 3 0 Translation machinery associated TMA7 APG6_N PF17675.1 EGG09240.1 - 0.27 11.8 14.1 0.7 10.4 14.1 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region CCDC-167 PF15188.6 EGG09240.1 - 0.95 9.8 17.2 0.33 11.3 0.8 3.1 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 Gon7 PF08738.10 EGG09241.1 - 0.047 13.8 1.6 3 8.0 0.1 3.1 2 0 0 2 2 2 0 Gon7 family Glyco_transf_90 PF05686.12 EGG09242.1 - 2e-35 122.5 0.9 3.4e-35 121.7 0.9 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 90 M11L PF11099.8 EGG09244.1 - 0.028 14.7 2.0 8.8 6.6 0.5 2.6 2 0 0 2 2 2 0 Apoptosis regulator M11L like DHFR_1 PF00186.19 EGG09245.1 - 2.9e-25 88.9 0.1 1.9e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 Dihydrofolate reductase Planc_extracel PF07595.12 EGG09251.1 - 2.1e-10 39.8 5.1 13 5.8 0.0 7.5 6 0 0 6 6 6 6 Planctomycete extracellular LD_cluster3 PF18180.1 EGG09251.1 - 0.049 13.3 26.8 15 5.2 0.1 9.4 7 3 3 12 12 12 0 SLOG cluster3 family Fungal_trans PF04082.18 EGG09252.1 - 2.4e-21 76.0 0.2 5.6e-21 74.8 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGG09252.1 - 0.011 15.9 13.2 0.011 15.9 13.2 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_2 PF00152.20 EGG09254.1 - 7.6e-81 271.6 0.0 9.2e-81 271.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGG09254.1 - 2.6e-09 37.0 0.2 5.3e-09 35.9 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PIN_9 PF18477.1 EGG09254.1 - 0.037 14.3 0.1 0.065 13.6 0.1 1.3 1 0 0 1 1 1 0 PIN like domain tRNA-synt_2d PF01409.20 EGG09254.1 - 0.051 13.1 0.1 4.2 6.8 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Toxin_7 PF05980.12 EGG09255.1 - 0.31 11.3 2.4 0.35 11.1 0.9 1.9 1 1 0 1 1 1 0 Toxin 7 NPV_P10 PF05531.12 EGG09259.1 - 0.0027 18.2 1.4 0.0074 16.7 1.4 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF1993 PF09351.10 EGG09259.1 - 0.0089 16.2 1.0 0.13 12.4 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1993) Ribosomal_S14 PF00253.21 EGG09261.1 - 1.6e-18 66.2 0.1 3e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF1556 PF07590.11 EGG09261.1 - 0.07 13.4 1.5 0.091 13.1 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1556) Mlo PF03094.15 EGG09262.1 - 0.15 10.4 0.1 0.18 10.2 0.1 1.1 1 0 0 1 1 1 0 Mlo family CSD PF00313.22 EGG09263.1 - 4e-19 68.2 1.4 8.1e-19 67.2 1.1 1.7 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain DHHC PF01529.20 EGG09265.1 - 1.4e-11 44.6 7.4 1.4e-11 44.6 7.4 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF2975 PF11188.8 EGG09265.1 - 0.014 15.3 2.3 0.029 14.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Actin PF00022.19 EGG09269.1 - 2.5e-125 418.3 0.0 1.2e-124 416.1 0.0 1.8 1 1 0 1 1 1 1 Actin Cutinase PF01083.22 EGG09270.1 - 1.5e-26 93.4 0.1 2e-26 93.1 0.1 1.1 1 0 0 1 1 1 1 Cutinase PGAP1 PF07819.13 EGG09270.1 - 0.0056 16.4 0.0 0.008 15.9 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein VirJ PF06057.11 EGG09270.1 - 0.03 14.2 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 EGG09270.1 - 0.071 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Cutinase PF01083.22 EGG09271.1 - 3.6e-27 95.5 0.2 4.7e-27 95.1 0.2 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_8 PF06259.12 EGG09271.1 - 0.00011 21.9 0.1 0.00029 20.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase PE-PPE PF08237.11 EGG09271.1 - 0.018 14.6 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.11 EGG09271.1 - 0.056 13.3 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) UPF0565 PF10561.9 EGG09271.1 - 0.3 10.2 0.0 0.37 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Asp PF00026.23 EGG09272.1 - 2.8e-18 66.4 0.2 9.1e-18 64.7 0.2 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG09272.1 - 2.9e-06 27.6 0.1 0.046 14.0 0.0 3.1 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Imm2 PF14426.6 EGG09273.1 - 0.069 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Immunity protein Imm2 HlyD_2 PF12700.7 EGG09273.1 - 0.17 10.5 9.3 0.065 12.0 4.5 1.9 2 0 0 2 2 2 0 HlyD family secretion protein NADH_oxidored PF08040.11 EGG09273.1 - 0.2 11.4 0.1 0.5 10.1 0.1 1.6 1 0 0 1 1 1 0 MNLL subunit AAA_assoc_2 PF16193.5 EGG09273.1 - 0.44 10.9 2.3 0.36 11.2 0.4 1.9 2 0 0 2 2 2 0 AAA C-terminal domain THOC7 PF05615.13 EGG09273.1 - 0.67 10.2 12.7 0.66 10.3 1.6 2.5 2 1 0 2 2 2 0 Tho complex subunit 7 Mucin PF01456.17 EGG09273.1 - 0.98 9.4 5.7 1.8 8.5 5.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein TEBP_beta PF07404.11 EGG09275.1 - 0.018 14.5 0.0 0.021 14.2 0.0 1.0 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) DUF3659 PF12396.8 EGG09275.1 - 0.088 12.7 0.1 0.61 10.0 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3659) Herpes_UL6 PF01763.16 EGG09275.1 - 0.19 10.2 0.0 0.21 10.1 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF2535 PF10751.9 EGG09276.1 - 0.038 14.5 0.3 0.069 13.7 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2535) GRASP55_65 PF04495.14 EGG09278.1 - 1.6e-60 203.4 0.0 1e-43 149.0 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EGG09278.1 - 1.7e-08 34.1 0.0 0.0058 16.4 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EGG09278.1 - 8.6e-08 32.4 0.0 2.1e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 PDZ domain HEPN_AbiA_CTD PF18732.1 EGG09278.1 - 0.22 11.5 0.5 0.39 10.7 0.5 1.3 1 0 0 1 1 1 0 HEPN like, Abia C-terminal domain Stealth_CR2 PF11380.8 EGG09279.1 - 2.8e-10 40.3 0.0 1.4e-07 31.7 0.0 2.7 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 EGG09279.1 - 1.1e-06 28.2 2.3 2.6e-06 27.0 2.3 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 EGG09279.1 - 6.5e-06 26.0 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 BCOR PF15808.5 EGG09279.1 - 0.13 12.5 1.5 0.23 11.7 1.5 1.3 1 0 0 1 1 1 0 BCL-6 co-repressor, non-ankyrin-repeat region BESS PF02944.20 EGG09280.1 - 0.034 14.0 14.9 26 4.8 0.1 6.0 5 1 1 6 6 6 0 BESS motif Thiolase_N PF00108.23 EGG09284.1 - 2.2e-72 243.6 0.0 3e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGG09284.1 - 5.3e-45 152.0 0.3 1.1e-44 151.0 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGG09284.1 - 0.0018 17.9 0.1 0.0033 17.0 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AA_permease_2 PF13520.6 EGG09285.1 - 4.3e-59 200.4 50.7 5.4e-59 200.1 50.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGG09285.1 - 1.2e-18 67.0 40.9 1.6e-18 66.6 40.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3902 PF13042.6 EGG09285.1 - 0.00046 19.8 0.4 0.00046 19.8 0.4 3.4 4 2 0 4 4 4 1 Protein of unknown function (DUF3902) DUF2098 PF09871.9 EGG09286.1 - 0.029 14.7 0.4 0.084 13.2 0.4 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) RNase_T PF00929.24 EGG09287.1 - 2.5e-19 70.4 0.0 4.6e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EGG09287.1 - 0.008 15.9 0.0 0.02 14.6 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease BAR PF03114.18 EGG09288.1 - 8.2e-55 186.1 2.3 1e-54 185.7 2.3 1.1 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EGG09288.1 - 0.00067 19.4 1.4 0.0016 18.2 1.4 1.7 1 1 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 EGG09288.1 - 0.019 14.5 5.6 0.23 11.0 5.6 2.0 1 1 0 1 1 1 0 Arfaptin-like domain TMPIT PF07851.13 EGG09288.1 - 0.55 9.4 1.8 1.9 7.6 0.1 1.9 1 1 1 2 2 2 0 TMPIT-like protein Chalcone_2 PF16035.5 EGG09289.1 - 1.4e-52 178.4 0.0 2e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EGG09289.1 - 3.6e-06 27.2 0.0 0.071 13.2 0.0 2.2 2 0 0 2 2 2 2 Chalcone isomerase-like Alpha-L-AF_C PF06964.12 EGG09290.1 - 4.2e-24 85.5 0.0 9.6e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Ceramidase_alk PF04734.13 EGG09290.1 - 0.17 10.5 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal PCI PF01399.27 EGG09295.1 - 8.9e-19 68.0 0.0 1.2e-17 64.3 0.0 2.7 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EGG09295.1 - 7.1e-11 42.0 0.2 2.4e-10 40.3 0.2 2.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF948 PF06103.11 EGG09295.1 - 0.89 9.8 8.5 1.4 9.2 0.3 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) RRM_1 PF00076.22 EGG09296.1 - 2.3e-18 65.8 0.0 3.6e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EGG09296.1 - 7.3e-06 26.4 0.2 7.3e-06 26.4 0.2 2.8 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 EGG09296.1 - 5.5e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EGG09296.1 - 0.05 13.7 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif MRP-S33 PF08293.11 EGG09297.1 - 1.1e-16 60.8 0.1 1.4e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 KDZ PF18758.1 EGG09298.1 - 1.3e-47 162.3 0.1 1e-44 152.8 0.1 2.5 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGG09298.1 - 0.00038 20.6 2.1 0.00038 20.6 0.0 2.0 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases PAS_8 PF13188.7 EGG09298.1 - 0.11 12.6 0.2 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 PAS domain SNF5 PF04855.12 EGG09299.1 - 1.1e-60 205.4 1.3 6.5e-59 199.6 1.3 2.0 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_C21 PF05381.12 EGG09299.1 - 0.077 13.4 0.0 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 Tymovirus endopeptidase TolB_N PF04052.13 EGG09299.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 TolB amino-terminal domain tRNA-synt_1b PF00579.25 EGG09300.1 - 1.3e-67 228.2 0.0 1.9e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 EGG09300.1 - 0.077 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 S4 domain GASA PF02704.14 EGG09301.1 - 0.053 13.7 1.0 0.096 12.8 0.5 1.7 1 1 1 2 2 2 0 Gibberellin regulated protein V-SNARE PF05008.15 EGG09303.1 - 0.02 15.3 0.8 0.044 14.2 0.8 1.6 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DnaJ_C PF01556.18 EGG09304.1 - 2.5e-38 131.5 0.0 3.4e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGG09304.1 - 3.5e-23 81.5 2.1 5.6e-23 80.8 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGG09304.1 - 3.6e-11 43.3 17.0 6.9e-11 42.3 17.0 1.5 1 0 0 1 1 1 1 DnaJ central domain LTXXQ PF07813.12 EGG09304.1 - 0.32 11.7 0.9 9.2 7.1 0.1 2.3 2 0 0 2 2 2 0 LTXXQ motif family protein Anti-TRAP PF15777.5 EGG09304.1 - 1.3 9.0 19.0 1.1 9.3 6.7 2.9 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGG09304.1 - 3.7 7.6 9.8 9 6.4 0.9 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA O-FucT PF10250.9 EGG09305.1 - 4.2e-05 23.4 0.1 0.35 10.5 0.0 2.4 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase RestrictionMunI PF11407.8 EGG09305.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme MunI Glyco_hydro_16 PF00722.21 EGG09306.1 - 1.7e-05 24.3 0.0 3.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 IPK PF03770.16 EGG09308.1 - 8.8e-34 117.1 0.0 9.2e-33 113.8 0.0 2.0 1 1 0 1 1 1 1 Inositol polyphosphate kinase Phosphodiest PF01663.22 EGG09310.1 - 2.7e-11 43.7 0.3 4.5e-11 42.9 0.3 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EGG09310.1 - 0.057 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Mito_carr PF00153.27 EGG09311.1 - 7.1e-50 166.9 1.5 6e-16 58.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGG09311.1 - 0.098 11.8 0.7 2.4 7.2 0.1 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease COG4 PF08318.12 EGG09313.1 - 1.1e-16 60.8 0.1 7.9e-08 31.7 0.0 2.1 2 0 0 2 2 2 2 COG4 transport protein Rrn6 PF10214.9 EGG09313.1 - 0.032 12.8 0.1 0.033 12.7 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ala_racemase_N PF01168.20 EGG09313.1 - 0.16 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain Sdh5 PF03937.16 EGG09314.1 - 0.033 14.2 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase MTA_R1 PF17226.2 EGG09316.1 - 0.0093 16.1 0.6 4.5 7.5 0.0 2.5 2 0 0 2 2 2 2 MTA R1 domain FapA PF03961.13 EGG09316.1 - 0.013 14.1 1.1 0.018 13.7 1.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2828 PF11443.8 EGG09316.1 - 0.061 11.4 0.5 0.1 10.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4795 PF16043.5 EGG09316.1 - 0.21 11.2 7.6 0.59 9.7 7.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) HalX PF08663.10 EGG09316.1 - 1.5 9.2 7.7 0.5 10.7 0.5 2.4 1 1 1 2 2 2 0 HalX domain Zn_clus PF00172.18 EGG09318.1 - 0.06 13.5 1.8 0.098 12.8 1.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FoP_duplication PF13865.6 EGG09319.1 - 0.0024 18.4 0.2 0.0039 17.7 0.2 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 SLAC1 PF03595.17 EGG09321.1 - 9e-24 84.3 21.0 1.2e-23 83.9 21.0 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3917 PF13055.6 EGG09321.1 - 1.9 8.9 5.3 14 6.2 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3917) Fig1 PF12351.8 EGG09321.1 - 4.5 7.2 6.9 1.2 9.0 2.0 2.1 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 CxC5 PF18718.1 EGG09323.1 - 1e-31 109.4 5.2 1.7e-31 108.7 5.2 1.4 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 EGG09323.1 - 0.027 14.3 0.4 0.056 13.3 0.1 1.7 2 0 0 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases Cas6 PF09559.10 EGG09323.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Cas6 Crispr Alpha_kinase PF02816.18 EGG09325.1 - 5.5e-08 33.1 0.1 1.8e-07 31.5 0.1 1.9 1 0 0 1 1 1 1 Alpha-kinase family Ribonuc_red_lgN PF00317.21 EGG09327.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain zf-CCHC PF00098.23 EGG09329.1 - 0.0019 18.2 2.3 0.0035 17.3 2.3 1.5 1 0 0 1 1 1 1 Zinc knuckle KCT2 PF17818.1 EGG09332.1 - 0.12 12.5 0.1 0.55 10.3 0.0 1.9 2 0 0 2 2 2 0 Keratinocyte-associated gene product ALG11_N PF15924.5 EGG09334.1 - 7.3e-07 29.4 0.5 1.1e-06 28.8 0.1 1.4 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus PAP2 PF01569.21 EGG09335.1 - 4e-09 36.4 5.5 6.1e-09 35.8 5.5 1.3 1 0 0 1 1 1 1 PAP2 superfamily PGG PF13962.6 EGG09335.1 - 0.0077 16.0 1.6 0.012 15.4 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF212 PF02681.14 EGG09335.1 - 0.014 15.5 3.0 0.088 12.9 1.7 2.5 2 1 0 2 2 2 0 Divergent PAP2 family BTB PF00651.31 EGG09336.1 - 0.0086 16.3 0.0 8.3 6.7 0.0 3.2 3 0 0 3 3 3 2 BTB/POZ domain NUC153 PF08159.12 EGG09336.1 - 7.4 6.5 5.5 47 3.9 0.1 3.4 3 0 0 3 3 3 0 NUC153 domain CFEM PF05730.11 EGG09337.1 - 1.7e-11 44.0 9.7 2e-11 43.8 9.7 1.1 1 0 0 1 1 1 1 CFEM domain Med21 PF11221.8 EGG09339.1 - 0.13 12.5 4.0 0.25 11.6 4.0 1.4 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Mucin PF01456.17 EGG09339.1 - 1.2 9.1 13.2 1.7 8.6 13.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 EGG09339.1 - 4.1 7.9 9.8 6.3 7.2 9.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Choline_transpo PF04515.12 EGG09340.1 - 1.2e-12 47.7 2.5 1.3e-12 47.6 2.5 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter TssN PF17555.2 EGG09340.1 - 0.17 11.2 1.1 0.19 11.1 1.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN PP_M1 PF03012.14 EGG09341.1 - 2.3 7.7 8.8 2.8 7.4 8.8 1.2 1 0 0 1 1 1 0 Phosphoprotein Ribosomal_S13_N PF08069.12 EGG09341.1 - 3.2 7.8 5.0 25 5.0 0.1 2.5 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain SRP-alpha_N PF04086.13 EGG09341.1 - 5.7 6.8 13.2 7 6.5 13.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Urm1 PF09138.11 EGG09345.1 - 1.5e-19 70.1 0.0 1.8e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EGG09345.1 - 0.14 12.8 0.0 0.18 12.5 0.0 1.4 1 1 0 1 1 1 0 ThiS family CxC6 PF18721.1 EGG09347.1 - 2.4e-17 62.9 2.8 2.4e-17 62.9 2.8 2.4 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 EGG09347.1 - 1.8e-08 34.4 2.6 1.8e-08 34.4 2.6 2.2 3 0 0 3 3 3 1 CxC5 like cysteine cluster associated with KDZ transposases ABA_GPCR PF12430.8 EGG09348.1 - 3e-21 76.0 12.5 3e-21 76.0 12.5 2.8 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EGG09348.1 - 3.9e-20 71.7 0.0 1.4e-19 69.9 0.0 2.0 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal GWT1 PF06423.12 EGG09348.1 - 0.29 11.2 5.2 2.3 8.3 3.4 3.0 2 1 0 2 2 2 0 GWT1 GH131_N PF18271.1 EGG09349.1 - 6.6e-12 45.7 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CAP PF00188.26 EGG09350.1 - 2.2e-15 57.6 1.7 3.9e-14 53.6 1.7 2.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family RRM_1 PF00076.22 EGG09351.1 - 2.9e-15 55.8 0.0 4.3e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG09351.1 - 2.3e-05 24.0 0.0 3.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG09351.1 - 0.0099 15.7 0.0 0.017 14.9 0.0 1.3 1 1 0 1 1 1 1 Occluded RNA-recognition motif NAM-associated PF14303.6 EGG09354.1 - 8.3e-05 23.4 4.6 0.0002 22.2 4.6 1.6 1 1 0 1 1 1 1 No apical meristem-associated C-terminal domain Motilin_assoc PF04643.12 EGG09354.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide DUF5407 PF17401.2 EGG09354.1 - 0.035 14.4 0.5 0.056 13.7 0.4 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5407) CARD PF00619.21 EGG09355.1 - 0.092 12.8 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Caspase recruitment domain CBP4 PF07960.11 EGG09357.1 - 0.0037 17.1 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 CBP4 Ribosomal_L18 PF17135.4 EGG09358.1 - 3.8e-88 293.8 0.9 4.2e-88 293.6 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EGG09358.1 - 0.032 14.9 0.0 0.032 14.9 0.0 2.2 2 1 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A CLIP_SPH_mas PF18398.1 EGG09359.1 - 0.16 12.4 0.1 0.36 11.3 0.1 1.6 1 0 0 1 1 1 0 Clip-domain serine protease homolog masquerade WW PF00397.26 EGG09360.1 - 0.0002 21.4 0.8 0.0002 21.4 0.8 2.4 2 0 0 2 2 2 1 WW domain DGF-1_C PF11040.8 EGG09360.1 - 4.3 7.4 5.2 11 6.1 5.2 1.8 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus BCDHK_Adom3 PF10436.9 EGG09361.1 - 1.6e-20 73.6 0.2 3.1e-20 72.6 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase GPP34 PF05719.11 EGG09362.1 - 3.8e-66 223.0 0.1 4.7e-66 222.7 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) FAD_binding_7 PF03441.14 EGG09365.1 - 1.2e-80 269.7 0.1 2.1e-80 269.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EGG09365.1 - 1.3e-38 132.5 0.3 2.5e-38 131.7 0.3 1.4 1 0 0 1 1 1 1 DNA photolyase Alpha_kinase PF02816.18 EGG09366.1 - 2.3e-14 53.9 0.4 2.7e-14 53.7 0.4 1.1 1 0 0 1 1 1 1 Alpha-kinase family BRE1 PF08647.11 EGG09367.1 - 0.0013 18.8 1.0 0.0013 18.8 1.0 3.6 3 1 1 4 4 4 1 BRE1 E3 ubiquitin ligase NPV_P10 PF05531.12 EGG09367.1 - 0.0017 18.8 6.5 0.025 15.0 0.1 3.9 3 2 0 3 3 3 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 EGG09367.1 - 0.034 14.2 0.9 0.034 14.2 0.9 3.0 2 1 1 3 3 3 0 Laminin Domain II Baculo_PEP_C PF04513.12 EGG09367.1 - 0.069 13.2 6.6 1.5 8.8 0.3 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YtxH PF12732.7 EGG09367.1 - 0.097 13.2 0.8 11 6.6 0.0 3.4 1 1 1 2 2 2 0 YtxH-like protein SYF2 PF08231.12 EGG09367.1 - 0.11 12.9 6.8 0.21 12.0 6.8 1.5 1 0 0 1 1 1 0 SYF2 splicing factor ATG16 PF08614.11 EGG09367.1 - 0.15 12.3 20.7 0.13 12.4 13.3 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MPS2 PF17060.5 EGG09367.1 - 0.26 10.5 15.0 0.12 11.6 2.3 2.8 1 1 0 2 2 2 0 Monopolar spindle protein 2 BioT2 PF15368.6 EGG09367.1 - 0.27 11.2 7.8 2.1 8.3 1.0 3.5 1 1 1 2 2 2 0 Spermatogenesis family BioT2 DDE_Tnp_IS66 PF03050.14 EGG09367.1 - 0.29 10.5 9.4 0.077 12.4 1.6 2.3 2 0 0 2 2 2 0 Transposase IS66 family DUF2884 PF11101.8 EGG09367.1 - 0.3 10.6 8.8 0.2 11.2 3.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) HAP1_N PF04849.13 EGG09367.1 - 0.36 10.0 18.9 1.9 7.6 15.4 2.8 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Fez1 PF06818.15 EGG09367.1 - 0.43 11.0 18.6 0.037 14.5 8.5 2.4 1 1 0 2 2 2 0 Fez1 MetOD2 PF18548.1 EGG09367.1 - 0.64 10.2 9.6 1.7 8.8 1.2 3.5 2 1 1 3 3 3 0 Metanogen output domain 2 FlaC_arch PF05377.11 EGG09367.1 - 0.72 10.3 8.3 1.3 9.5 0.0 3.9 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 EGG09367.1 - 0.87 10.1 15.8 0.18 12.3 1.7 3.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 zf-C4H2 PF10146.9 EGG09367.1 - 1.6 9.0 16.1 0.13 12.5 9.5 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein Allexi_40kDa PF05549.11 EGG09367.1 - 1.9 8.0 12.5 0.13 11.7 3.8 2.5 1 1 2 3 3 3 0 Allexivirus 40kDa protein SlyX PF04102.12 EGG09367.1 - 2.6 8.7 16.0 4.3 8.0 0.5 4.5 2 1 1 4 4 4 0 SlyX Fib_alpha PF08702.10 EGG09367.1 - 2.7 8.2 12.7 0.09 13.0 1.2 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF489 PF04356.12 EGG09367.1 - 2.9 7.8 7.9 2 8.4 0.4 2.7 2 1 0 3 3 2 0 Protein of unknown function (DUF489) Med9 PF07544.13 EGG09367.1 - 4.3 7.5 12.2 3 8.0 2.6 3.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 RNase_J_C PF17770.1 EGG09367.1 - 5.1 8.2 5.3 6.3 7.9 0.3 3.0 3 1 0 3 3 3 0 Ribonuclease J C-terminal domain Spc7 PF08317.11 EGG09367.1 - 5.5 5.8 21.3 9.9 4.9 17.7 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 EGG09367.1 - 6.4 4.6 8.9 11 3.8 8.6 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Cep57_MT_bd PF06657.13 EGG09367.1 - 6.4 7.3 17.2 3.4 8.2 3.2 4.1 3 1 1 4 4 3 0 Centrosome microtubule-binding domain of Cep57 DUF883 PF05957.13 EGG09367.1 - 6.8 7.4 8.7 18 6.0 1.1 3.5 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) CorA PF01544.18 EGG09367.1 - 7.5 5.8 9.5 1.1 8.5 4.5 2.0 2 1 1 3 3 2 0 CorA-like Mg2+ transporter protein DUF4709 PF15821.5 EGG09367.1 - 8.5 6.7 12.1 0.43 10.9 1.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4709) XhlA PF10779.9 EGG09367.1 - 8.9 6.6 14.0 12 6.1 0.3 4.4 3 1 2 5 5 5 0 Haemolysin XhlA Sad1_UNC PF07738.13 EGG09368.1 - 3.3e-29 101.6 0.1 5.4e-29 100.9 0.1 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF1091 PF06477.13 EGG09368.1 - 0.061 13.8 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) UreD PF01774.17 EGG09368.1 - 0.072 13.0 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 UreD urease accessory protein FliJ PF02050.16 EGG09374.1 - 0.024 14.9 2.0 0.043 14.0 1.9 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein Apolipoprotein PF01442.18 EGG09374.1 - 0.059 13.2 4.4 0.098 12.5 4.4 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CENP-F_leu_zip PF10473.9 EGG09374.1 - 0.073 13.1 10.6 0.032 14.3 5.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Noelin-1 PF12308.8 EGG09374.1 - 0.16 11.9 1.2 0.39 10.7 1.2 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein NPV_P10 PF05531.12 EGG09374.1 - 0.17 12.3 4.9 0.12 12.8 1.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 EGG09374.1 - 0.36 11.5 7.1 0.09 13.4 2.4 2.3 2 0 0 2 2 2 0 SlyX DUF4665 PF15679.5 EGG09374.1 - 0.42 11.3 5.9 16 6.2 1.7 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4665) DUF4988 PF16378.5 EGG09374.1 - 0.46 10.1 3.3 0.26 10.9 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function TMF_DNA_bd PF12329.8 EGG09374.1 - 4.3 7.4 13.5 0.43 10.6 4.7 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2802 PF10975.8 EGG09374.1 - 4.6 7.4 5.8 26 5.0 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DHR10 PF18595.1 EGG09374.1 - 7.3 6.7 12.4 2.2 8.4 6.3 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain His_Phos_2 PF00328.22 EGG09376.1 - 1.6e-46 159.4 0.0 1.9e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) bPH_6 PF10756.9 EGG09377.1 - 0.0018 18.3 2.6 9.1 6.5 0.1 4.1 1 1 2 3 3 3 2 Bacterial PH domain TFIIA PF03153.13 EGG09377.1 - 0.18 11.8 36.0 0.23 11.4 36.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PTPRCAP PF15713.5 EGG09377.1 - 1 9.6 16.6 0.43 10.9 12.4 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Med19 PF10278.9 EGG09377.1 - 1.2 9.0 31.6 3.5 7.5 23.0 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.12 EGG09377.1 - 1.6 8.5 24.8 0.35 10.7 19.2 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4770 PF15994.5 EGG09377.1 - 2.7 8.2 15.9 11 6.2 10.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Coilin_N PF15862.5 EGG09377.1 - 5 6.9 28.1 2.3 8.0 18.9 2.5 2 0 0 2 2 2 0 Coilin N-terminus Vfa1 PF08432.10 EGG09377.1 - 5.9 7.2 28.2 2.6 8.4 21.2 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Stealth_CR2 PF11380.8 EGG09378.1 - 0.11 12.7 1.9 0.17 12.1 1.9 1.4 1 1 0 1 1 1 0 Stealth protein CR2, conserved region 2 Pkinase PF00069.25 EGG09381.1 - 2.6e-10 40.1 0.2 1.3e-09 37.9 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG09381.1 - 0.006 15.9 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DASH_Dad2 PF08654.10 EGG09383.1 - 0.067 13.6 0.9 0.21 12.0 0.9 1.9 1 0 0 1 1 1 0 DASH complex subunit Dad2 ArsA_HSP20 PF17886.1 EGG09388.1 - 0.12 11.9 0.1 0.41 10.2 0.0 1.9 2 1 0 2 2 2 0 HSP20-like domain found in ArsA Metallophos PF00149.28 EGG09389.1 - 9.1e-37 127.5 0.6 1.2e-36 127.2 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGG09389.1 - 0.01 16.3 1.1 0.02 15.3 1.1 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 EGG09389.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain F-box-like PF12937.7 EGG09394.1 - 0.21 11.5 1.7 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 F-box-like Glyco_hydro_26 PF02156.15 EGG09395.1 - 8.1e-14 51.8 0.5 1.2e-13 51.2 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 LMWPc PF01451.21 EGG09399.1 - 2.1e-31 109.2 0.0 2.8e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase F-box-like PF12937.7 EGG09400.1 - 9.9e-05 22.2 0.1 0.073 13.0 0.1 3.0 2 0 0 2 2 2 2 F-box-like LRR_4 PF12799.7 EGG09400.1 - 0.011 16.1 3.4 9.8 6.8 2.2 4.4 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) Ldh_1_C PF02866.18 EGG09401.1 - 8.1e-16 58.4 0.0 9.6e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain adh_short_C2 PF13561.6 EGG09402.1 - 3.8e-42 144.4 0.0 5.4e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG09402.1 - 2.3e-39 134.9 0.0 3.1e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG09402.1 - 2.7e-07 30.7 0.1 4.6e-07 29.9 0.1 1.5 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGG09402.1 - 0.0026 17.2 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 EGG09402.1 - 0.0084 16.0 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EGG09402.1 - 0.017 14.2 0.1 0.025 13.7 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 EGG09402.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EGG09402.1 - 0.03 13.8 0.3 0.097 12.1 0.3 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 EGG09402.1 - 0.049 14.1 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 EGG09402.1 - 0.072 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EGG09402.1 - 0.088 12.0 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 EGG09402.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zf-H2C2_2 PF13465.6 EGG09403.1 - 1.4e-06 28.5 3.3 1.4e-06 28.5 3.3 3.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGG09403.1 - 0.00054 20.3 3.1 0.00054 20.3 3.1 3.3 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 EGG09403.1 - 0.0028 18.2 8.1 1.5 9.5 0.3 3.5 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EGG09403.1 - 0.063 14.2 7.3 0.4 11.6 3.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf_ZIC PF18366.1 EGG09403.1 - 2 8.6 5.2 2.2 8.5 0.5 2.9 3 0 0 3 3 3 0 Zic proteins zinc finger domain Viral_RdRp_C PF17501.2 EGG09405.1 - 0.023 15.2 2.9 0.023 15.2 2.9 2.3 1 1 1 2 2 2 0 Viral RNA-directed RNA polymerase Macoilin PF09726.9 EGG09405.1 - 0.24 9.9 8.4 0.28 9.7 8.4 1.0 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_12 PF01670.16 EGG09410.1 - 9e-24 84.7 3.9 1.1e-23 84.3 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Agenet PF05641.12 EGG09412.1 - 0.066 13.7 0.0 8.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Agenet domain G-alpha PF00503.20 EGG09413.1 - 4.3e-112 374.8 0.4 5.1e-112 374.6 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGG09413.1 - 2.4e-16 59.7 0.1 5.6e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG09413.1 - 1.7e-05 24.3 0.3 0.13 11.6 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGG09413.1 - 0.0029 17.8 0.3 0.85 9.8 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGG09413.1 - 0.031 14.0 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGG09413.1 - 0.06 13.4 0.1 5 7.2 0.1 3.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG09413.1 - 0.16 11.5 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain GlgS PF08971.11 EGG09416.1 - 0.036 14.1 0.3 0.085 12.9 0.3 1.6 1 0 0 1 1 1 0 Glycogen synthesis protein ICEA PF05315.11 EGG09416.1 - 0.051 13.0 0.5 0.15 11.5 0.5 1.7 1 0 0 1 1 1 0 ICEA Protein HCV_capsid PF01543.17 EGG09416.1 - 2.6 8.3 15.9 3.4 7.9 0.7 3.7 1 1 2 3 3 3 0 Hepatitis C virus capsid protein Lsr2 PF11774.8 EGG09416.1 - 3.8 7.7 8.9 0.24 11.5 1.8 2.6 2 0 0 2 2 2 0 Lsr2 TANGO2 PF05742.12 EGG09418.1 - 9.4e-37 127.4 6.3 2.2e-36 126.2 6.3 1.5 1 1 0 1 1 1 1 Transport and Golgi organisation 2 GBP_repeat PF02526.14 EGG09418.1 - 0.015 15.0 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 Glycophorin-binding protein E1-E2_ATPase PF00122.20 EGG09421.1 - 7e-46 156.0 0.8 7e-46 156.0 0.8 2.5 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGG09421.1 - 1.2e-34 119.6 3.0 1.2e-34 119.6 3.0 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGG09421.1 - 3.6e-19 69.9 1.3 2.9e-15 57.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG09421.1 - 3.1e-07 30.4 0.0 6.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGG09421.1 - 1.3e-06 28.0 0.0 3.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG09421.1 - 0.00025 20.9 1.0 0.0083 15.9 0.6 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG09421.1 - 0.013 16.0 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 EGG09421.1 - 0.11 12.4 0.8 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Phage_holin_1 PF04531.13 EGG09421.1 - 0.12 13.0 1.1 12 6.5 0.0 4.3 5 0 0 5 5 5 0 Bacteriophage holin DUF2570 PF10828.8 EGG09422.1 - 0.0034 17.2 1.3 0.0074 16.1 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) Myb_DNA-bind_4 PF13837.6 EGG09422.1 - 0.014 15.8 1.6 0.029 14.7 0.3 2.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain PhoLip_ATPase_N PF16209.5 EGG09423.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipid-translocating ATPase N-terminal Use1 PF09753.9 EGG09424.1 - 0.0039 16.9 0.5 0.0049 16.6 0.5 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.13 EGG09424.1 - 0.013 15.4 0.9 0.024 14.6 0.8 1.5 1 1 0 1 1 1 0 Sec20 SNARE PF05739.19 EGG09424.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 SNARE domain Chitin_synth_1N PF08407.11 EGG09425.1 - 3.4e-18 65.4 0.0 4.6e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase N-terminal DLH PF01738.18 EGG09426.1 - 1.4e-16 60.7 0.0 3.8e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2002 PF09400.10 EGG09426.1 - 0.057 13.4 0.0 0.25 11.4 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2002) FMN_dh PF01070.18 EGG09427.1 - 1.7e-117 392.4 0.0 2e-117 392.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EGG09427.1 - 5.4e-18 64.9 0.1 1.6e-17 63.4 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EGG09427.1 - 3.4e-05 23.1 0.0 0.0001 21.6 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 EGG09427.1 - 6.5e-05 22.1 0.0 0.00011 21.3 0.0 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EGG09427.1 - 0.024 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 EGG09427.1 - 0.034 13.5 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EGG09427.1 - 0.066 12.7 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein zf-C3HC4_3 PF13920.6 EGG09428.1 - 3.6e-09 36.4 6.7 7.4e-09 35.3 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG09428.1 - 2.2e-08 33.8 9.6 6.2e-08 32.4 9.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG09428.1 - 2.7e-08 34.0 9.5 2.7e-08 34.0 9.5 2.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG09428.1 - 1.4e-07 31.3 9.0 3.2e-07 30.1 9.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGG09428.1 - 0.0012 19.1 5.8 0.0012 19.1 5.8 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGG09428.1 - 0.0033 17.3 8.3 0.0086 16.0 8.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGG09428.1 - 0.0061 16.4 7.7 0.0061 16.4 7.7 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EGG09428.1 - 1.6 8.6 8.2 0.71 9.7 4.7 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 EGG09428.1 - 7.6 6.8 10.7 10 6.4 9.2 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING SNAP PF14938.6 EGG09431.1 - 3.3e-106 354.8 9.7 3.7e-106 354.7 9.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Spatacsin_C PF14649.6 EGG09431.1 - 1.8e-05 24.0 3.1 0.00027 20.1 0.2 2.7 1 1 1 3 3 3 1 Spatacsin C-terminus TPR_2 PF07719.17 EGG09431.1 - 0.0041 17.1 9.5 10 6.5 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGG09431.1 - 0.0091 15.4 0.0 0.05 13.0 0.0 2.0 1 1 1 2 2 2 1 MalT-like TPR region MIT PF04212.18 EGG09431.1 - 0.0097 16.0 1.4 3.4 7.8 0.1 3.5 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EGG09431.1 - 0.022 15.4 1.2 1.3e+02 3.6 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGG09431.1 - 0.023 15.2 6.3 1.3 9.6 0.1 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG09431.1 - 1.3 9.3 6.2 12 6.2 0.2 3.5 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_28 PF00295.17 EGG09432.1 - 4.5e-44 150.8 1.5 5.7e-44 150.5 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Ribosomal_L33 PF00471.20 EGG09435.1 - 0.0009 19.6 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L33 DUF5545 PF17699.1 EGG09435.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5545) DUF3437 PF11919.8 EGG09436.1 - 4.7 7.2 5.2 1.8 8.5 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) HEAT_EZ PF13513.6 EGG09439.1 - 7.7e-27 93.3 15.0 4.5e-11 43.0 0.1 10.9 12 0 0 12 12 11 3 HEAT-like repeat HEAT PF02985.22 EGG09439.1 - 1e-21 75.1 8.6 0.00029 20.9 0.0 8.9 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 EGG09439.1 - 6.7e-15 55.2 0.0 0.00017 21.9 0.0 5.5 4 2 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 EGG09439.1 - 1.5e-06 28.3 0.0 0.13 12.3 0.0 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 EGG09439.1 - 2.1e-05 24.4 0.0 0.00019 21.3 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 EGG09439.1 - 6.7e-05 21.6 0.0 0.0098 14.5 0.0 3.2 2 1 1 3 3 3 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 EGG09439.1 - 0.00011 22.8 0.0 0.55 10.9 0.0 4.7 4 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 EGG09439.1 - 0.00024 21.1 0.7 0.044 13.8 0.0 3.1 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central Arm PF00514.23 EGG09439.1 - 0.0024 17.9 11.0 1.6 8.9 0.1 6.5 7 0 0 7 7 5 1 Armadillo/beta-catenin-like repeat Xpo1 PF08389.12 EGG09439.1 - 0.005 16.9 0.1 0.45 10.6 0.0 3.5 4 0 0 4 4 4 1 Exportin 1-like protein DUF3437 PF11919.8 EGG09439.1 - 0.04 13.8 0.0 20 5.2 0.0 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) DRIM PF07539.12 EGG09439.1 - 0.065 11.5 0.1 7.8 4.7 0.0 2.9 4 0 0 4 4 4 0 Down-regulated in metastasis MMS19_C PF12460.8 EGG09439.1 - 0.13 11.4 11.3 0.2 10.7 0.1 4.4 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal TAF6_C PF07571.13 EGG09439.1 - 0.14 12.5 0.0 1.6 9.1 0.0 2.7 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain F-box PF00646.33 EGG09441.1 - 0.023 14.6 0.1 0.15 12.0 0.0 2.5 2 0 0 2 2 2 0 F-box domain Kunitz_BPTI PF00014.23 EGG09442.1 - 0.045 14.0 3.5 0.093 13.0 3.5 1.6 1 1 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Acyl_transf_3 PF01757.22 EGG09444.1 - 4.9e-29 101.5 24.8 7.6e-29 100.8 24.8 1.3 1 0 0 1 1 1 1 Acyltransferase family RRN3 PF05327.11 EGG09445.1 - 9.4e-156 519.6 0.0 1.1e-155 519.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Med5 PF08689.10 EGG09445.1 - 0.032 12.1 0.1 0.045 11.6 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 IDO PF01231.18 EGG09446.1 - 3e-35 121.9 0.0 4e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TPR_2 PF07719.17 EGG09447.1 - 1.2e-11 43.7 5.2 0.014 15.4 0.2 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.24 EGG09447.1 - 3.2e-11 43.0 0.1 5.5e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_8 PF13181.6 EGG09447.1 - 3.8e-08 32.9 0.8 0.0068 16.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG09447.1 - 4.3e-07 29.5 6.2 0.0045 16.8 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG09447.1 - 8.8e-06 25.9 3.0 0.00017 21.8 0.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG09447.1 - 0.00031 20.4 3.2 0.0032 17.1 0.1 3.7 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 EGG09447.1 - 0.0057 17.3 6.8 0.042 14.5 0.9 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG09447.1 - 0.018 15.6 2.8 92 4.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG09447.1 - 0.034 14.2 5.4 2.2 8.5 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGG09447.1 - 0.038 13.4 2.0 3 7.4 0.0 2.7 3 0 0 3 3 3 0 SHNi-TPR TPR_10 PF13374.6 EGG09447.1 - 0.13 12.1 2.3 45 4.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4795 PF16043.5 EGG09449.1 - 0.00042 20.0 0.8 0.00087 18.9 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Atg14 PF10186.9 EGG09449.1 - 0.004 16.3 3.6 0.0066 15.6 3.6 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 CCDC53 PF10152.9 EGG09449.1 - 0.023 15.1 0.9 0.023 15.1 0.9 2.2 2 1 0 2 2 1 0 Subunit CCDC53 of WASH complex DUF711 PF05167.12 EGG09449.1 - 0.027 13.4 0.5 0.037 12.9 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) Syntaxin-6_N PF09177.11 EGG09449.1 - 0.027 15.0 2.3 0.072 13.7 2.3 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Paralemmin PF03285.15 EGG09449.1 - 0.034 13.7 4.8 0.074 12.6 4.8 1.5 1 0 0 1 1 1 0 Paralemmin DUF3450 PF11932.8 EGG09449.1 - 0.081 12.2 6.8 0.13 11.5 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fmp27_WPPW PF10359.9 EGG09449.1 - 0.1 11.5 3.6 0.14 11.0 3.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Bcr-Abl_Oligo PF09036.10 EGG09449.1 - 0.12 12.4 2.4 0.46 10.5 0.1 2.5 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Baculo_F PF12259.8 EGG09449.1 - 0.15 10.5 0.1 1.5 7.2 0.3 1.9 2 0 0 2 2 2 0 Baculovirus F protein NPV_P10 PF05531.12 EGG09449.1 - 0.19 12.2 4.7 0.25 11.8 0.7 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 EGG09449.1 - 0.28 11.6 8.5 1.7 9.0 4.7 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BMFP PF04380.13 EGG09449.1 - 0.42 11.1 8.7 0.56 10.7 0.2 2.8 2 0 0 2 2 2 0 Membrane fusogenic activity DUF745 PF05335.13 EGG09449.1 - 0.44 10.2 3.0 0.76 9.5 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) UPF0242 PF06785.11 EGG09449.1 - 0.48 10.5 4.4 0.74 9.9 4.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Tropomyosin_1 PF12718.7 EGG09449.1 - 0.58 10.3 9.6 2.7 8.1 9.8 1.8 1 1 1 2 2 2 0 Tropomyosin like Lzipper-MIP1 PF14389.6 EGG09449.1 - 0.59 10.5 8.1 1.9 8.9 8.1 1.9 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF4094 PF13334.6 EGG09449.1 - 0.59 10.6 2.4 5 7.6 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) SlyX PF04102.12 EGG09449.1 - 0.61 10.7 9.9 14 6.4 9.9 2.6 1 1 0 1 1 1 0 SlyX ADIP PF11559.8 EGG09449.1 - 0.99 9.5 9.4 4 7.5 1.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TRAF_BIRC3_bd PF16673.5 EGG09449.1 - 2.1 8.2 6.1 13 5.6 5.8 2.2 1 1 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain BLOC1_2 PF10046.9 EGG09449.1 - 2.8 8.3 6.0 9.9 6.5 0.3 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm1_N PF18504.1 EGG09449.1 - 4.8 7.6 7.9 35 4.8 3.4 2.8 1 1 1 2 2 2 0 Csm1 N-terminal domain ABC_tran_CTD PF16326.5 EGG09449.1 - 8.8 6.7 12.3 13 6.1 8.6 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain Prenyltrans PF00432.21 EGG09451.1 - 1e-12 47.6 0.0 6.9e-08 32.1 0.0 2.9 3 0 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat AFT PF08731.11 EGG09456.1 - 7.8e-06 26.3 0.4 2.3e-05 24.7 0.4 1.8 1 0 0 1 1 1 1 Transcription factor AFT FAR1 PF03101.15 EGG09456.1 - 0.00034 21.2 0.3 0.00076 20.1 0.3 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain UPF0227 PF05728.12 EGG09457.1 - 0.027 14.4 0.7 0.06 13.3 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF948 PF06103.11 EGG09458.1 - 0.009 16.3 1.2 0.019 15.2 1.2 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 EGG09458.1 - 0.022 15.2 1.2 0.051 14.0 1.2 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein RPW8 PF05659.11 EGG09458.1 - 0.12 12.1 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 GLTP PF08718.11 EGG09458.1 - 0.17 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) DUF1754 PF08555.10 EGG09459.1 - 0.014 16.1 2.3 0.031 15.1 2.3 1.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) CFEM PF05730.11 EGG09460.1 - 1.7e-12 47.2 9.7 3.5e-12 46.2 9.7 1.5 1 0 0 1 1 1 1 CFEM domain DUF908 PF06012.12 EGG09460.1 - 0.0045 16.4 17.5 0.0045 16.4 17.5 3.0 1 1 1 2 2 2 1 Domain of Unknown Function (DUF908) DUF4349 PF14257.6 EGG09462.1 - 0.00058 19.4 1.1 0.001 18.6 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) Fib_alpha PF08702.10 EGG09462.1 - 0.028 14.6 0.6 0.074 13.2 0.2 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HBM PF16591.5 EGG09462.1 - 0.067 12.6 5.7 0.12 11.7 5.7 1.4 1 0 0 1 1 1 0 Helical bimodular sensor domain FTA4 PF13093.6 EGG09462.1 - 0.15 11.9 3.8 0.4 10.5 3.6 1.7 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 SWIRM-assoc_1 PF16495.5 EGG09462.1 - 0.23 11.4 5.4 0.54 10.3 1.5 2.5 2 0 0 2 2 2 0 SWIRM-associated region 1 UPF0242 PF06785.11 EGG09462.1 - 0.37 10.9 4.4 0.74 9.9 4.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 EGG09462.1 - 0.55 10.6 4.4 3.4 8.0 0.1 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Occludin_ELL PF07303.13 EGG09462.1 - 3.5 8.4 6.2 1.4 9.7 0.9 2.7 2 1 1 3 3 3 0 Occludin homology domain Spc7 PF08317.11 EGG09462.1 - 5.7 5.7 10.5 0.52 9.1 5.9 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Rnk_N PF14760.6 EGG09462.1 - 9.4 6.8 7.4 12 6.5 0.5 2.8 2 0 0 2 2 2 0 Rnk N-terminus Rsbr_N PF08678.10 EGG09464.1 - 0.087 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Rsbr N terminal Ecl1 PF12855.7 EGG09465.1 - 8.8e-06 27.0 26.6 1.2e-05 26.6 26.6 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins Apt1 PF10351.9 EGG09465.1 - 0.18 10.6 12.3 0.21 10.4 12.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 EGG09465.1 - 1.9 7.2 6.9 2.1 7.0 6.9 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 EGG09465.1 - 6.3 5.2 15.4 7.5 5.0 15.4 1.2 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 EGG09465.1 - 7 6.2 27.7 0.92 9.1 22.3 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NUDIX PF00293.28 EGG09466.1 - 4.1e-11 43.0 0.1 8.9e-11 42.0 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain CybS PF05328.12 EGG09467.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit Striatin PF08232.12 EGG09469.1 - 0.19 12.3 1.8 0.31 11.6 1.8 1.3 1 0 0 1 1 1 0 Striatin family Gpr1_Fun34_YaaH PF01184.19 EGG09470.1 - 1.3e-84 283.0 20.8 1.6e-84 282.6 20.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2244 PF10003.9 EGG09470.1 - 7 6.3 9.0 11 5.7 8.3 1.7 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) PAP2 PF01569.21 EGG09471.1 - 1.3e-27 96.2 1.1 1.3e-27 96.2 1.1 2.0 1 1 1 2 2 2 2 PAP2 superfamily MNHE PF01899.16 EGG09471.1 - 0.069 12.9 0.1 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit Orf78 PF06024.12 EGG09473.1 - 0.15 12.3 0.1 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) GCM PF03615.15 EGG09474.1 - 0.0023 17.8 3.8 0.023 14.6 3.8 2.5 1 1 0 1 1 1 1 GCM motif protein GAGA_bind PF06217.12 EGG09474.1 - 0.12 12.6 9.6 0.28 11.4 9.6 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Endostatin PF06482.11 EGG09474.1 - 2.4 7.5 10.5 4.9 6.5 10.5 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Zip PF02535.22 EGG09474.1 - 4.9 6.3 8.5 8.1 5.6 8.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 EGG09474.1 - 6.6 5.6 13.1 12 4.8 13.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 EGG09474.1 - 7.1 6.4 19.2 1.6 8.5 15.7 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 zf-C2H2 PF00096.26 EGG09475.1 - 1.3e-06 28.5 12.4 9e-05 22.7 0.8 3.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG09475.1 - 0.00026 21.5 13.0 0.031 15.1 0.7 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger PH_9 PF15410.6 EGG09477.1 - 1.6e-29 102.7 0.0 3.4e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 EGG09477.1 - 6.5e-29 100.9 0.3 1.1e-28 100.1 0.3 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EGG09477.1 - 0.0011 19.4 0.0 0.0033 17.9 0.0 1.8 1 0 0 1 1 1 1 PH domain AcMNPV_Ac109 PF05054.12 EGG09479.1 - 0.068 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF4148 PF13663.6 EGG09481.1 - 0.089 13.0 0.7 0.12 12.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Ras PF00071.22 EGG09483.1 - 4e-43 146.8 0.0 5.3e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG09483.1 - 7.7e-28 97.1 0.0 1.1e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG09483.1 - 2e-10 40.4 0.0 7.3e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG09483.1 - 0.0001 21.9 0.0 0.00048 19.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EGG09483.1 - 0.00042 20.6 0.0 0.0007 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG09483.1 - 0.00093 19.6 0.1 0.0053 17.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 EGG09483.1 - 0.0012 18.2 0.0 0.0024 17.3 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGG09483.1 - 0.0046 16.9 0.0 0.35 10.8 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EGG09483.1 - 0.0073 16.4 0.0 0.018 15.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EGG09483.1 - 0.016 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGG09483.1 - 0.064 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EGG09483.1 - 0.07 13.6 0.4 0.12 12.9 0.0 1.7 2 1 0 2 2 2 0 ABC transporter TniB PF05621.11 EGG09483.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 EGG09483.1 - 0.21 11.0 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 EGG09483.1 - 0.33 10.7 1.9 0.34 10.7 0.0 2.0 2 0 0 2 2 1 0 P-loop containing region of AAA domain CP2 PF04516.15 EGG09484.1 - 0.0043 16.4 0.3 0.0056 16.0 0.3 1.2 1 0 0 1 1 1 1 CP2 transcription factor DUF4840 PF16128.5 EGG09484.1 - 0.011 15.7 0.3 0.023 14.8 0.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4840) FlaG PF03646.15 EGG09484.1 - 1.3 9.2 9.7 0.078 13.2 3.1 2.0 2 0 0 2 2 2 0 FlaG protein YL1_C PF08265.11 EGG09485.1 - 8.1e-16 57.5 0.1 1e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain GFP PF01353.22 EGG09486.1 - 0.024 14.1 0.1 0.05 13.1 0.1 1.4 1 0 0 1 1 1 0 Green fluorescent protein Arm PF00514.23 EGG09486.1 - 0.57 10.3 4.9 3.9 7.7 0.0 4.0 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat DUF2833 PF11090.8 EGG09490.1 - 0.15 12.5 0.5 0.34 11.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) Peptidase_C62 PF12380.8 EGG09490.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase ThiF PF00899.21 EGG09495.1 - 5.3e-105 350.1 0.0 2.1e-69 233.6 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGG09495.1 - 5.8e-87 291.8 0.0 1.1e-86 290.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EGG09495.1 - 5.3e-34 116.8 1.5 1e-33 115.8 1.5 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 EGG09495.1 - 4.3e-31 106.9 0.2 1.2e-30 105.5 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EGG09495.1 - 1.4e-27 95.7 0.5 3.9e-27 94.2 0.5 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle End_beta_barrel PF12195.8 EGG09495.1 - 0.059 13.3 0.0 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase NUDE_C PF04880.13 EGG09497.1 - 1.1e-12 48.7 15.3 1.1e-12 48.7 15.3 4.3 2 1 2 4 4 1 1 NUDE protein, C-terminal conserved region DUF2353 PF09789.9 EGG09497.1 - 0.00036 20.0 22.7 0.013 14.9 9.4 2.3 1 1 1 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) Prefoldin_2 PF01920.20 EGG09497.1 - 0.00052 19.9 16.6 0.0022 17.9 4.2 4.2 2 1 0 3 3 3 1 Prefoldin subunit TolA_bind_tri PF16331.5 EGG09497.1 - 0.0019 18.2 2.9 0.0019 18.2 2.9 4.1 3 1 1 4 4 4 2 TolA binding protein trimerisation ZapB PF06005.12 EGG09497.1 - 0.0042 17.5 1.1 0.0042 17.5 1.1 4.1 2 1 2 4 4 3 2 Cell division protein ZapB DMPK_coil PF08826.10 EGG09497.1 - 0.011 15.8 0.8 0.011 15.8 0.8 4.0 1 1 2 3 3 3 0 DMPK coiled coil domain like CCDC144C PF14915.6 EGG09497.1 - 0.037 13.2 20.3 0.088 11.9 20.3 1.6 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Spc7 PF08317.11 EGG09497.1 - 0.09 11.6 21.7 0.82 8.5 5.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein NAGLU_C PF12972.7 EGG09497.1 - 0.1 12.1 3.1 0.2 11.2 3.1 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain IFT57 PF10498.9 EGG09497.1 - 0.1 11.6 14.7 0.13 11.2 2.8 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 GAS PF13851.6 EGG09497.1 - 0.12 11.7 19.6 0.064 12.6 14.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Rab5-bind PF09311.11 EGG09497.1 - 0.2 11.0 18.7 0.75 9.1 18.7 1.8 1 1 0 1 1 1 0 Rabaptin-like protein Baculo_PEP_C PF04513.12 EGG09497.1 - 0.22 11.6 5.2 0.27 11.2 1.6 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.11 EGG09497.1 - 0.28 11.0 16.8 0.029 14.2 5.4 3.5 2 1 2 4 4 4 0 Phage minor structural protein GP20 DivIC PF04977.15 EGG09497.1 - 0.3 10.9 15.2 0.097 12.4 1.4 3.9 3 1 1 4 4 4 0 Septum formation initiator TPR_MLP1_2 PF07926.12 EGG09497.1 - 0.31 11.1 25.7 0.64 10.1 6.5 3.7 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 EGG09497.1 - 0.41 11.1 25.4 0.3 11.5 13.3 3.2 1 1 1 2 2 2 0 Fez1 Metal_resist PF13801.6 EGG09497.1 - 0.48 10.6 8.3 7.2 6.8 0.1 3.5 3 0 0 3 3 3 0 Heavy-metal resistance DUF3584 PF12128.8 EGG09497.1 - 0.48 7.9 15.7 0.8 7.1 15.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2390 PF09523.10 EGG09497.1 - 0.52 10.7 7.6 2.7 8.4 2.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) PspA_IM30 PF04012.12 EGG09497.1 - 0.7 9.4 15.7 0.41 10.2 10.7 2.3 1 1 1 2 2 2 0 PspA/IM30 family DUF4200 PF13863.6 EGG09497.1 - 0.7 10.3 21.9 0.18 12.2 5.6 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) Filament PF00038.21 EGG09497.1 - 1.1 8.8 25.7 0.4 10.2 13.2 2.7 2 1 1 3 3 3 0 Intermediate filament protein SOGA PF11365.8 EGG09497.1 - 1.2 10.4 15.0 5.5 8.2 2.4 4.0 3 1 1 4 4 3 0 Protein SOGA EzrA PF06160.12 EGG09497.1 - 1.8 6.6 16.8 3.5 5.7 16.8 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Atg14 PF10186.9 EGG09497.1 - 2.4 7.2 22.1 0.071 12.2 4.6 3.2 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF148 PF02520.17 EGG09497.1 - 2.7 8.1 7.0 2.1 8.5 5.2 1.7 2 0 0 2 2 1 0 Domain of unknown function DUF148 FPP PF05911.11 EGG09497.1 - 4.4 5.4 23.3 42 2.1 23.4 2.3 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil Fzo_mitofusin PF04799.13 EGG09497.1 - 5 6.6 9.3 0.65 9.5 2.1 2.8 1 1 1 2 2 2 0 fzo-like conserved region Snapin_Pallidin PF14712.6 EGG09497.1 - 6.3 7.3 12.9 0.2 12.1 2.3 3.6 2 1 1 4 4 3 0 Snapin/Pallidin FlaC_arch PF05377.11 EGG09497.1 - 8.2 6.9 9.4 22 5.5 0.7 4.1 1 1 2 4 4 4 0 Flagella accessory protein C (FlaC) KxDL PF10241.9 EGG09497.1 - 8.9 6.7 11.4 16 5.9 2.9 3.8 1 1 2 3 3 3 0 Uncharacterized conserved protein HMMR_N PF15905.5 EGG09497.1 - 9.1 5.6 24.5 9.7 5.6 20.3 2.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF812 PF05667.11 EGG09497.1 - 9.9 4.9 22.2 6 5.6 18.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF812) ANAPC4 PF12896.7 EGG09498.1 - 1.7e-17 63.6 0.1 2.9e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EGG09498.1 - 0.031 14.6 0.0 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG09498.1 - 0.036 14.9 0.1 1.2 10.2 0.0 3.2 2 0 0 2 2 2 0 WD domain, G-beta repeat CDK2AP PF09806.9 EGG09499.1 - 0.099 12.7 0.1 0.099 12.7 0.1 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein LRR_4 PF12799.7 EGG09501.1 - 0.077 13.5 14.9 9.7 6.8 0.7 6.7 4 3 2 6 6 6 0 Leucine Rich repeats (2 copies) LSM PF01423.22 EGG09502.1 - 9e-11 41.3 0.1 1.3e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGG09502.1 - 1.5e-05 25.0 0.0 2e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF3533 PF12051.8 EGG09503.1 - 3.7e-89 299.3 17.6 4.8e-89 298.9 17.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) COX4 PF02936.14 EGG09503.1 - 0.0085 16.1 0.0 0.03 14.3 0.0 1.9 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF4131 PF13567.6 EGG09503.1 - 2.5 7.8 9.6 0.81 9.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Aminotran_1_2 PF00155.21 EGG09504.1 - 2.7e-90 303.2 0.0 3.1e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1057 PF06342.12 EGG09506.1 - 0.041 12.9 0.1 0.66 9.0 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) GCM PF03615.15 EGG09506.1 - 0.061 13.2 3.0 0.058 13.3 1.0 1.9 2 0 0 2 2 2 0 GCM motif protein Lyase_1 PF00206.20 EGG09508.1 - 2.3e-113 378.7 0.0 3.4e-113 378.1 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EGG09508.1 - 5.4e-20 71.6 1.7 5.1e-19 68.4 0.0 2.8 3 0 0 3 3 3 1 Fumarase C C-terminus Engrail_1_C_sig PF10525.9 EGG09508.1 - 0.19 11.0 1.9 7.9 5.8 0.3 2.4 2 0 0 2 2 2 0 Engrailed homeobox C-terminal signature domain Glyco_transf_8 PF01501.20 EGG09509.1 - 3e-19 69.6 0.4 4.9e-18 65.6 0.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGG09509.1 - 0.083 12.2 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative K_trans PF02705.16 EGG09512.1 - 2.5e-152 508.2 17.0 1.5e-147 492.4 19.9 2.1 2 0 0 2 2 2 2 K+ potassium transporter NCBP3 PF10309.9 EGG09513.1 - 1.8e-07 30.9 0.0 3.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 EGG09513.1 - 0.03 14.3 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain Macoilin PF09726.9 EGG09513.1 - 9.4 4.7 8.5 0.67 8.4 3.9 1.3 2 0 0 2 2 2 0 Macoilin family VHS PF00790.19 EGG09514.1 - 5.2e-21 75.0 0.0 1.4e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EGG09514.1 - 0.16 12.3 1.7 0.28 11.5 0.8 1.9 2 0 0 2 2 2 0 GAT domain WD40 PF00400.32 EGG09515.1 - 3e-17 62.7 7.2 0.0044 17.8 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG09515.1 - 0.036 14.4 0.0 1.5 9.2 0.0 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PASTA PF03793.19 EGG09515.1 - 0.037 13.9 0.2 0.087 12.7 0.2 1.6 1 0 0 1 1 1 0 PASTA domain Alpha_kinase PF02816.18 EGG09516.1 - 6.4e-07 29.7 0.0 7.2e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Alpha-kinase family RuvB_N PF05496.12 EGG09516.1 - 0.03 14.1 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF3155 PF11352.8 EGG09516.1 - 0.038 14.4 0.0 0.059 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) Bse634I PF07832.11 EGG09516.1 - 0.065 12.6 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Cfr10I/Bse634I restriction endonuclease Asp_protease_2 PF13650.6 EGG09518.1 - 0.071 13.8 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 EGG09518.1 - 0.087 13.4 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-Tim10_DDP PF02953.15 EGG09520.1 - 2e-22 78.6 0.9 2.4e-22 78.3 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pescadillo_N PF06732.11 EGG09520.1 - 0.13 11.8 0.0 0.15 11.5 0.0 1.0 1 0 0 1 1 1 0 Pescadillo N-terminus SBBP PF06739.11 EGG09521.1 - 0.11 12.5 0.3 0.32 11.0 0.3 1.8 1 0 0 1 1 1 0 Beta-propeller repeat Ribosomal_L1 PF00687.21 EGG09522.1 - 7.2e-17 61.8 0.1 8e-17 61.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Myosin_head PF00063.21 EGG09525.1 - 1.3e-11 43.5 0.0 1.4e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) WD40 PF00400.32 EGG09528.1 - 1.2e-17 63.9 15.6 1.6e-06 28.7 0.0 8.0 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG09528.1 - 2.8e-15 56.4 0.2 0.001 19.3 0.0 5.8 2 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG09528.1 - 0.00028 20.3 0.8 0.02 14.2 0.0 2.9 3 1 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 EGG09528.1 - 0.00054 19.0 0.9 0.76 8.7 0.0 3.2 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGG09528.1 - 0.0051 16.7 0.7 2.3 8.1 0.0 3.3 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 EGG09528.1 - 0.016 14.8 0.0 0.27 10.8 0.0 2.4 1 1 1 2 2 2 0 PQQ-like domain PD40 PF07676.12 EGG09528.1 - 0.018 14.9 0.0 1.1 9.2 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 EGG09530.1 - 1.6e-19 70.6 0.0 5.5e-19 68.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG09530.1 - 0.00095 19.8 0.0 0.0012 19.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG09530.1 - 0.0047 16.2 0.0 0.19 11.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DnaJ PF00226.31 EGG09531.1 - 3.4e-18 65.5 1.3 6.9e-18 64.5 0.5 2.0 2 0 0 2 2 2 1 DnaJ domain IDEAL PF08858.10 EGG09531.1 - 0.049 13.4 0.9 4.2 7.2 0.0 2.6 2 0 0 2 2 2 0 IDEAL domain MU117 PF15474.6 EGG09532.1 - 0.0064 17.3 0.4 0.0092 16.8 0.4 1.3 1 0 0 1 1 1 1 Meiotically up-regulated gene family Selenoprotein_S PF06936.11 EGG09533.1 - 0.93 9.3 13.2 1.6 8.5 13.2 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) SRP-alpha_N PF04086.13 EGG09533.1 - 0.96 9.3 12.5 1.4 8.8 12.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Bd3614_N PF14442.6 EGG09533.1 - 2.4 8.5 8.2 2.2 8.6 2.7 2.9 2 1 1 3 3 3 0 Bd3614-like deaminase N-terminal Noggin PF05806.12 EGG09533.1 - 2.6 7.9 6.4 2.8 7.8 4.3 1.9 1 1 1 2 2 2 0 Noggin MPM1 PF17234.2 EGG09533.1 - 5.1 7.3 7.3 79 3.4 7.4 2.4 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 RapA_C PF12137.8 EGG09533.1 - 6 5.8 13.1 16 4.4 11.9 1.9 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal Toxin_37 PF11415.8 EGG09537.1 - 0.45 10.4 5.0 7.2 6.5 0.1 3.2 3 0 0 3 3 3 0 Antifungal peptide termicin MIP PF00230.20 EGG09538.1 - 2.8e-21 76.3 15.4 4e-21 75.8 15.4 1.2 1 0 0 1 1 1 1 Major intrinsic protein D123 PF07065.14 EGG09540.1 - 1.4e-84 283.9 0.3 2.2e-84 283.2 0.3 1.3 1 1 0 1 1 1 1 D123 FH2 PF02181.23 EGG09541.1 - 1.3e-59 202.2 18.2 1.8e-59 201.8 3.6 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain Drf_GBD PF06371.13 EGG09541.1 - 2.6e-40 138.0 0.0 2.6e-40 138.0 0.0 2.7 3 1 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGG09541.1 - 5.4e-36 124.0 0.1 5.4e-36 124.0 0.1 3.1 4 0 0 4 4 4 1 Diaphanous FH3 Domain SQHop_cyclase_N PF13249.6 EGG09542.1 - 2.3e-47 161.5 3.1 8.9e-40 136.6 0.0 4.0 3 1 2 5 5 5 4 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EGG09542.1 - 4.1e-47 160.8 4.7 7.2e-43 146.9 3.7 2.6 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 EGG09542.1 - 1.7e-31 107.6 6.4 2e-10 40.2 0.1 6.0 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EGG09542.1 - 0.00017 20.7 5.1 0.0026 16.8 0.8 3.0 3 1 0 3 3 3 2 A-macroglobulin TED domain Pec_lyase PF09492.10 EGG09542.1 - 0.00076 18.9 5.3 2.7 7.2 0.0 4.9 4 2 2 6 6 6 2 Pectic acid lyase G-patch PF01585.23 EGG09543.1 - 2.9e-13 49.5 4.0 5.2e-13 48.6 4.0 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EGG09543.1 - 7.1e-12 45.0 0.0 4.3e-07 29.7 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 EGG09543.1 - 1.3e-06 28.4 0.4 1.3e-06 28.4 0.4 2.1 2 0 0 2 2 2 1 G-patch domain zf-C2H2_3rep PF18868.1 EGG09543.1 - 0.067 13.9 0.6 0.16 12.7 0.6 1.7 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats OPT PF03169.15 EGG09549.1 - 2.4e-160 535.2 39.4 2.7e-160 535.0 39.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Inhibitor_Mig-6 PF11555.8 EGG09550.1 - 0.029 14.4 0.6 0.029 14.4 0.6 2.4 1 1 1 2 2 2 0 EGFR receptor inhibitor Mig-6 DUF4831 PF16115.5 EGG09551.1 - 0.027 13.5 1.0 0.033 13.3 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4831) D123 PF07065.14 EGG09551.1 - 0.03 13.5 3.0 0.035 13.3 3.0 1.1 1 0 0 1 1 1 0 D123 DUF4770 PF15994.5 EGG09551.1 - 0.061 13.6 2.7 0.07 13.4 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Neur_chan_memb PF02932.16 EGG09551.1 - 0.073 13.1 1.9 0.081 13.0 1.9 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Uds1 PF15456.6 EGG09551.1 - 0.14 12.3 4.8 0.21 11.8 4.8 1.2 1 0 0 1 1 1 0 Up-regulated During Septation Adeno_terminal PF02459.15 EGG09551.1 - 0.15 10.4 4.8 0.18 10.2 4.8 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein RP-C_C PF11800.8 EGG09551.1 - 0.2 11.7 2.8 0.23 11.6 2.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Pox_Ag35 PF03286.14 EGG09551.1 - 0.39 10.5 7.2 0.53 10.0 7.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 EGG09551.1 - 2.7 6.2 7.7 2.7 6.2 7.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EGG09551.1 - 3.3 6.4 4.3 3.5 6.3 4.3 1.0 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 EGG09552.1 - 1.5e-32 112.9 30.3 1.4e-25 90.0 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG09552.1 - 3.3e-24 85.6 13.5 4.7e-24 85.1 13.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter BTV_NS2 PF04514.12 EGG09552.1 - 0.24 10.2 0.0 0.37 9.6 0.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CxC1 PF18802.1 EGG09555.1 - 0.018 15.1 0.5 0.042 14.0 0.1 1.9 2 0 0 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases Alpha_kinase PF02816.18 EGG09556.1 - 1.2e-07 32.0 0.1 3.6e-07 30.5 0.1 1.8 1 1 1 2 2 2 1 Alpha-kinase family DNA_pol_phi PF04931.13 EGG09557.1 - 0.32 9.1 7.4 0.34 9.0 7.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 EGG09557.1 - 5.1 6.1 11.6 6.1 5.9 11.6 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 EGG09557.1 - 8 5.7 10.2 8.5 5.6 10.2 1.1 1 0 0 1 1 1 0 NOA36 protein Prefoldin_2 PF01920.20 EGG09561.1 - 3.6e-20 71.9 1.6 3.9e-20 71.8 1.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit ZapB PF06005.12 EGG09561.1 - 0.00084 19.7 4.6 0.0057 17.1 4.6 2.1 1 1 0 1 1 1 1 Cell division protein ZapB SMC_ScpB PF04079.16 EGG09561.1 - 0.0044 16.6 0.3 0.017 14.7 0.1 1.8 2 0 0 2 2 2 1 Segregation and condensation complex subunit ScpB Phage_Mu_Gam PF07352.12 EGG09561.1 - 0.0049 16.8 0.3 0.0059 16.5 0.3 1.1 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Seryl_tRNA_N PF02403.22 EGG09561.1 - 0.0083 16.3 0.4 0.31 11.3 0.0 2.2 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain V-ATPase_C PF03223.15 EGG09561.1 - 0.018 14.5 0.7 0.078 12.4 0.2 1.8 2 0 0 2 2 2 0 V-ATPase subunit C Tropomyosin_1 PF12718.7 EGG09561.1 - 0.018 15.2 0.7 0.68 10.1 0.0 2.0 2 0 0 2 2 2 0 Tropomyosin like APG6_N PF17675.1 EGG09561.1 - 0.022 15.3 3.5 2 8.9 0.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region APG17 PF04108.12 EGG09561.1 - 0.023 13.8 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 GAS PF13851.6 EGG09561.1 - 0.028 13.8 1.6 1 8.7 0.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding betaPIX_CC PF16523.5 EGG09561.1 - 0.04 13.7 0.7 0.082 12.7 0.1 1.7 2 0 0 2 2 2 0 betaPIX coiled coil Syntaxin-6_N PF09177.11 EGG09561.1 - 0.076 13.6 0.6 1.9 9.1 0.0 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TrmB PF01978.19 EGG09561.1 - 0.081 12.8 0.3 2.6 8.0 0.0 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB ROS_MUCR PF05443.11 EGG09561.1 - 0.082 13.0 1.0 0.71 9.9 1.0 2.1 1 1 0 1 1 1 0 ROS/MUCR transcriptional regulator protein TMF_DNA_bd PF12329.8 EGG09561.1 - 0.23 11.5 4.6 0.39 10.8 0.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Snf7 PF03357.21 EGG09561.1 - 0.41 10.2 3.3 0.93 9.1 0.6 2.0 1 1 1 2 2 2 0 Snf7 zf-RING_4 PF14570.6 EGG09562.1 - 0.38 10.6 7.8 0.34 10.7 3.9 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Peptidase_C48 PF02902.19 EGG09564.1 - 6.2e-34 117.7 2.3 1.4e-33 116.6 2.3 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 EGG09564.1 - 0.012 14.3 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase zf-CCCH_2 PF14608.6 EGG09566.1 - 2e-06 28.0 19.6 0.00022 21.6 6.7 4.2 4 0 0 4 4 4 2 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 EGG09566.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Methyltransf_16 PF10294.9 EGG09567.1 - 3e-12 46.6 0.0 6.5e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Chromo PF00385.24 EGG09567.1 - 0.14 12.1 0.4 1.6 8.7 0.3 2.4 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.29 EGG09569.1 - 2.4e-40 138.0 0.0 4.1e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EGG09569.1 - 4.7e-25 87.4 0.0 1.4e-24 85.9 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EGG09569.1 - 9e-22 76.9 4.4 2.1e-21 75.8 4.4 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EGG09569.1 - 1.1e-06 28.3 0.0 4.9e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EGG09569.1 - 1.5e-05 25.5 0.1 0.00027 21.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGG09569.1 - 3.8e-05 23.7 0.0 0.00011 22.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGG09569.1 - 5.8e-05 23.4 1.0 0.013 15.8 0.0 3.7 4 0 0 4 4 4 1 RNA helicase RuvB_N PF05496.12 EGG09569.1 - 6.4e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGG09569.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EGG09569.1 - 0.00014 21.2 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EGG09569.1 - 0.00019 21.7 0.4 0.021 15.1 0.0 2.7 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.13 EGG09569.1 - 0.00028 20.2 0.0 0.0044 16.2 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EGG09569.1 - 0.00034 20.7 0.0 0.00096 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EGG09569.1 - 0.001 19.2 0.0 0.03 14.4 0.0 2.5 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EGG09569.1 - 0.0011 19.6 0.2 0.0044 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGG09569.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGG09569.1 - 0.0056 16.4 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGG09569.1 - 0.011 15.3 0.1 0.83 9.2 0.1 2.5 1 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGG09569.1 - 0.023 15.1 0.1 0.076 13.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 EGG09569.1 - 0.027 14.4 0.0 1.5 8.7 0.0 2.6 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EGG09569.1 - 0.033 14.1 0.0 0.28 11.1 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 EGG09569.1 - 0.034 13.5 0.0 0.087 12.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGG09569.1 - 0.051 13.1 0.0 0.15 11.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF5355 PF17306.2 EGG09569.1 - 0.068 12.2 1.0 0.11 11.5 0.6 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5355) Parvo_NS1 PF01057.17 EGG09569.1 - 0.069 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 EGG09569.1 - 0.093 12.2 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 EGG09569.1 - 0.12 11.7 0.0 6.6 6.0 0.0 2.3 1 1 1 2 2 2 0 KaiC Torsin PF06309.11 EGG09569.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin CPT PF07931.12 EGG09569.1 - 0.15 11.9 0.0 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein HMG14_17 PF01101.18 EGG09569.1 - 1.7 9.6 5.7 3.7 8.6 5.7 1.6 1 0 0 1 1 1 0 HMG14 and HMG17 Asp PF00026.23 EGG09571.1 - 2.4e-55 188.2 5.8 2.9e-55 187.9 5.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG09571.1 - 3.8e-10 40.3 6.4 2.7e-08 34.3 5.7 3.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal ChiC PF06483.11 EGG09571.1 - 0.0053 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Chitinase C Poxvirus_B22R_N PF13169.6 EGG09574.1 - 0.0093 16.4 0.7 5.4 7.6 0.1 2.6 2 0 0 2 2 2 2 Poxvirus B22R protein N-terminal rhaM PF05336.13 EGG09574.1 - 0.57 10.3 11.0 0.069 13.2 1.7 3.1 1 1 1 3 3 3 0 L-rhamnose mutarotase RRM_1 PF00076.22 EGG09575.1 - 4.9e-07 29.5 0.0 8.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2OG-FeII_Oxy_2 PF13532.6 EGG09579.1 - 4.5e-11 43.3 0.0 5.4e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DSPc PF00782.20 EGG09583.1 - 9.8e-28 96.6 0.0 1.3e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGG09583.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EGG09583.1 - 0.046 13.3 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Vps5 PF09325.10 EGG09584.1 - 4.8e-09 36.1 3.8 1e-08 35.0 3.8 1.6 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EGG09584.1 - 1.9e-08 34.3 0.1 4.3e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 PX domain Cro PF09048.10 EGG09584.1 - 0.038 14.0 0.2 0.084 12.9 0.2 1.5 1 0 0 1 1 1 0 Cro Arfaptin PF06456.13 EGG09584.1 - 0.065 12.8 3.3 0.071 12.7 0.0 2.4 3 0 0 3 3 3 0 Arfaptin-like domain DUF4349 PF14257.6 EGG09584.1 - 0.071 12.5 1.5 0.39 10.1 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) MecA_N PF05223.11 EGG09584.1 - 0.72 10.1 4.0 5 7.4 0.9 2.5 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain Cation_efflux PF01545.21 EGG09587.1 - 2.9e-19 69.6 3.6 3.8e-19 69.2 3.6 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGG09587.1 - 1e-08 35.1 0.1 3e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter Pept_S41_N PF18294.1 EGG09587.1 - 0.077 13.0 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Peptidase S41 N-terminal domain Phasin_2 PF09361.10 EGG09587.1 - 0.11 12.7 1.5 0.13 12.5 0.3 1.8 2 0 0 2 2 2 0 Phasin protein SNAD4 PF18750.1 EGG09587.1 - 0.12 12.6 0.1 1.1 9.4 0.1 2.2 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 Lipase_3 PF01764.25 EGG09588.1 - 2.2e-15 56.8 0.1 5.3e-12 45.8 0.1 2.5 2 0 0 2 2 2 2 Lipase (class 3) UPF0227 PF05728.12 EGG09588.1 - 0.023 14.7 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.7 EGG09588.1 - 0.043 14.4 0.1 0.082 13.5 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Serglycin PF04360.12 EGG09588.1 - 1.2 9.0 7.5 0.23 11.4 1.8 2.4 2 0 0 2 2 2 0 Serglycin YL1 PF05764.13 EGG09589.1 - 0.37 10.9 5.1 3.7 7.6 0.2 2.0 1 1 0 2 2 2 0 YL1 nuclear protein MCLC PF05934.11 EGG09590.1 - 0.097 11.4 8.3 0.12 11.1 8.3 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Macoilin PF09726.9 EGG09590.1 - 0.33 9.5 13.6 0.35 9.4 13.6 1.0 1 0 0 1 1 1 0 Macoilin family XRCC4 PF06632.12 EGG09590.1 - 1.9 7.3 10.7 2.3 7.0 10.7 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 GREB1 PF15782.5 EGG09590.1 - 1.9 5.5 10.4 2.2 5.3 10.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SRP-alpha_N PF04086.13 EGG09590.1 - 2.4 8.0 11.0 2.7 7.8 11.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal UPF0121 PF03661.13 EGG09591.1 - 3.6e-65 219.7 5.5 4.3e-65 219.5 5.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) MCM PF00493.23 EGG09595.1 - 1.4e-102 341.5 0.3 2.5e-102 340.7 0.3 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGG09595.1 - 2e-38 131.0 0.2 4.3e-38 130.0 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EGG09595.1 - 1.2e-27 96.3 2.7 2.9e-27 95.0 2.7 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EGG09595.1 - 3.2e-26 91.6 0.7 8.8e-26 90.2 0.1 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EGG09595.1 - 5.4e-18 65.5 0.5 1.5e-17 64.1 0.5 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGG09595.1 - 1.6e-08 34.2 0.0 3.4e-07 29.9 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGG09595.1 - 0.00097 19.0 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGG09595.1 - 0.0032 17.2 0.0 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EGG09595.1 - 0.0073 16.3 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) SapB_1 PF05184.15 EGG09595.1 - 4.7 7.3 6.2 1.8 8.6 0.7 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 CxC6 PF18721.1 EGG09598.1 - 5.7e-22 77.8 1.4 2.1e-21 75.9 1.4 2.0 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 EGG09598.1 - 4.2e-17 62.3 7.6 1.5e-09 37.9 1.6 3.1 2 1 1 3 3 3 2 CxC5 like cysteine cluster associated with KDZ transposases F-box-like PF12937.7 EGG09599.1 - 0.0023 17.8 0.0 0.0085 16.0 0.0 2.0 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 EGG09601.1 - 0.063 13.2 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 F-box-like TPR_12 PF13424.6 EGG09603.1 - 1.8e-14 53.8 1.1 1.4e-09 38.1 0.2 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-MYND PF01753.18 EGG09603.1 - 1.1e-08 35.0 16.4 1.8e-08 34.3 16.4 1.4 1 0 0 1 1 1 1 MYND finger TPR_2 PF07719.17 EGG09603.1 - 1.1e-08 34.6 2.4 0.17 12.0 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG09603.1 - 1.6e-08 34.1 0.5 0.055 13.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGG09603.1 - 1.5e-07 31.1 1.2 0.025 14.4 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGG09603.1 - 2e-06 27.4 1.2 0.15 12.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG09603.1 - 5e-06 26.9 0.9 2.4e-05 24.8 0.3 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG09603.1 - 5.6e-06 26.0 0.9 0.21 11.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EGG09603.1 - 3.7e-05 23.9 0.5 0.019 15.6 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG09603.1 - 0.00091 19.8 0.3 1.2 9.8 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG09603.1 - 0.0014 19.2 1.6 0.76 10.8 0.4 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG09603.1 - 0.0077 16.5 1.7 13 6.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat T2SSF PF00482.23 EGG09603.1 - 0.019 14.9 0.2 0.035 14.0 0.2 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F ANAPC3 PF12895.7 EGG09603.1 - 0.038 14.2 3.8 1.1 9.6 0.2 3.4 1 1 3 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 EGG09603.1 - 0.049 13.3 0.2 0.23 11.1 0.1 2.1 1 1 2 3 3 3 0 26S proteasome subunit RPN7 TPR_MalT PF17874.1 EGG09603.1 - 0.051 12.9 0.2 0.078 12.3 0.2 1.3 1 1 0 1 1 1 0 MalT-like TPR region TPR_21 PF09976.9 EGG09603.1 - 0.097 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 EGG09603.1 - 0.43 11.3 3.4 66 4.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C6H2 PF15801.5 EGG09603.1 - 6.3 7.2 16.6 25 5.3 16.6 2.0 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TPR_12 PF13424.6 EGG09604.1 - 2.7e-11 43.6 1.9 2.3e-06 27.8 1.3 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-MYND PF01753.18 EGG09604.1 - 7.6e-08 32.3 17.4 1.6e-07 31.3 17.4 1.6 1 0 0 1 1 1 1 MYND finger TPR_8 PF13181.6 EGG09604.1 - 3.6e-07 29.9 3.4 0.0026 17.8 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG09604.1 - 2.4e-06 27.2 2.9 0.047 13.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGG09604.1 - 3.2e-06 26.8 0.5 0.0016 18.3 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG09604.1 - 6e-06 25.9 2.9 0.087 12.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG09604.1 - 8.9e-05 22.3 0.1 0.23 11.6 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.9 EGG09604.1 - 0.0014 18.4 0.4 0.082 12.6 0.1 2.3 1 1 1 2 2 2 1 26S proteasome subunit RPN7 TPR_MalT PF17874.1 EGG09604.1 - 0.0038 16.6 0.1 0.0048 16.3 0.1 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_17 PF13431.6 EGG09604.1 - 0.0054 17.0 0.8 3.1 8.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG09604.1 - 0.024 15.1 0.1 0.11 13.0 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG09604.1 - 0.049 14.3 0.2 11 6.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Septin PF00735.18 EGG09605.1 - 9.4e-116 386.0 0.2 1.7e-115 385.2 0.2 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGG09605.1 - 4.1e-08 33.3 0.9 1.2e-07 31.7 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG09605.1 - 1.3e-05 25.2 1.1 0.00056 19.8 0.1 2.8 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EGG09605.1 - 3.8e-05 23.3 3.3 0.00023 20.7 0.0 3.1 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EGG09605.1 - 0.00042 20.8 4.3 0.016 15.8 0.0 2.8 2 1 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 EGG09605.1 - 0.00059 19.9 0.7 0.0064 16.6 0.0 2.8 2 1 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 EGG09605.1 - 0.001 19.4 0.4 0.013 15.8 0.0 2.6 2 2 1 3 3 3 1 AAA domain AAA_16 PF13191.6 EGG09605.1 - 0.0022 18.4 0.0 0.006 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 EGG09605.1 - 0.005 16.4 0.1 0.031 13.9 0.0 2.3 2 0 0 2 2 2 1 Ras family AIG1 PF04548.16 EGG09605.1 - 0.006 15.9 0.2 0.025 13.9 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_29 PF13555.6 EGG09605.1 - 0.011 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EGG09605.1 - 0.039 14.2 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EGG09605.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGG09605.1 - 0.088 12.6 0.1 4.6 7.0 0.0 3.3 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EGG09605.1 - 0.14 12.5 0.3 0.79 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Exonuc_VII_L PF02601.15 EGG09605.1 - 0.15 11.6 4.4 0.25 10.9 4.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Strep_SA_rep PF06696.11 EGG09605.1 - 4.1 7.5 7.6 0.89 9.6 0.1 2.6 2 0 0 2 2 2 0 Streptococcal surface antigen repeat MBOAT_2 PF13813.6 EGG09607.1 - 4.5e-11 42.9 2.2 1.1e-10 41.6 2.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF5475 PF17569.2 EGG09607.1 - 0.22 11.8 0.7 0.39 11.1 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5475) MBOAT_2 PF13813.6 EGG09610.1 - 5.4e-10 39.4 2.2 9.9e-10 38.6 2.2 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Ras PF00071.22 EGG09611.1 - 7.5e-64 214.2 0.3 8.8e-64 214.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG09611.1 - 2.4e-35 121.3 0.3 3.5e-35 120.8 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG09611.1 - 2.8e-13 49.7 0.1 3.7e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG09611.1 - 5.9e-08 32.8 0.1 9.9e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG09611.1 - 3.8e-05 23.6 0.2 0.013 15.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGG09611.1 - 0.00026 20.4 0.3 0.00047 19.6 0.3 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGG09611.1 - 0.00043 19.9 0.2 0.0016 18.0 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EGG09611.1 - 0.0011 19.2 0.1 0.0038 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EGG09611.1 - 0.0077 15.7 0.0 0.011 15.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGG09611.1 - 0.015 15.7 0.1 0.025 15.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EGG09611.1 - 0.019 15.5 0.1 0.03 14.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter DUF3533 PF12051.8 EGG09611.1 - 0.025 13.5 0.5 0.029 13.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) AAA_7 PF12775.7 EGG09611.1 - 0.027 14.0 0.1 0.14 11.6 0.0 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 EGG09611.1 - 0.027 14.5 0.1 0.085 12.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EGG09611.1 - 0.043 13.2 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 EGG09611.1 - 0.057 12.5 0.0 0.12 11.4 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain AAA_24 PF13479.6 EGG09611.1 - 0.058 13.1 0.1 0.14 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF1128 PF06569.11 EGG09611.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) AAA_5 PF07728.14 EGG09611.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EGG09611.1 - 0.12 12.1 0.4 0.19 11.5 0.4 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system CHAP PF05257.16 EGG09611.1 - 0.13 12.9 0.1 0.24 12.0 0.1 1.4 1 0 0 1 1 1 0 CHAP domain GCM PF03615.15 EGG09612.1 - 0.026 14.4 2.1 0.083 12.8 2.1 1.8 1 1 0 1 1 1 0 GCM motif protein GIT1_C PF12205.8 EGG09613.1 - 0.074 13.2 3.5 0.082 13.0 0.0 2.4 2 1 1 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term Ribosomal_S13 PF00416.22 EGG09614.1 - 3.3e-18 66.3 0.1 7.8e-12 45.7 0.3 2.0 2 0 0 2 2 2 2 Ribosomal protein S13/S18 Pput2613-deam PF14427.6 EGG09614.1 - 0.045 13.7 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Pput_2613-like deaminase LRR_9 PF14580.6 EGG09615.1 - 1.6e-45 154.7 1.9 2.7e-45 154.0 1.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGG09615.1 - 1.1e-11 44.8 15.1 1.1e-07 32.0 5.9 4.1 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG09615.1 - 9.4e-09 34.9 10.7 2e-07 30.6 6.6 3.3 2 2 1 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 EGG09615.1 - 0.00028 21.0 12.8 0.021 15.3 0.6 5.1 5 0 0 5 5 5 2 Leucine Rich Repeat NESP55 PF06390.12 EGG09615.1 - 0.14 11.8 4.8 0.2 11.2 4.8 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) LRR_6 PF13516.6 EGG09615.1 - 0.5 10.6 10.1 23 5.4 0.3 4.6 5 0 0 5 5 5 0 Leucine Rich repeat TP53IP5 PF15331.6 EGG09615.1 - 7.5 6.6 9.7 12 6.0 9.7 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 TT_ORF2 PF02957.15 EGG09616.1 - 0.0045 17.9 0.9 0.014 16.3 0.9 1.8 1 0 0 1 1 1 1 TT viral ORF2 DUF4266 PF14086.6 EGG09616.1 - 0.25 12.3 0.7 7.1 7.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) Glyco_hydro_26 PF02156.15 EGG09617.1 - 3.7e-05 23.3 0.3 5.1e-05 22.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Alpha_adaptin_C PF02296.16 EGG09617.1 - 0.31 11.3 1.0 14 5.9 0.0 2.2 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain Glyco_hydro_26 PF02156.15 EGG09618.1 - 7.7e-05 22.3 0.2 0.00011 21.7 0.2 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 26 SNF2_N PF00176.23 EGG09619.1 - 5.3e-47 160.2 0.1 8.5e-47 159.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG09619.1 - 1.1e-15 57.9 0.0 2.6e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-PHD-like PF15446.6 EGG09619.1 - 3.7e-06 26.7 1.8 3.7e-06 26.7 1.8 3.1 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain ResIII PF04851.15 EGG09619.1 - 3.6e-05 23.8 0.0 0.00014 21.9 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.24 EGG09619.1 - 3.7e-05 23.5 0.7 0.094 12.6 0.0 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 EGG09619.1 - 0.0013 18.6 2.4 0.0013 18.6 2.4 3.2 4 0 0 4 4 4 2 PHD-finger Zf_RING PF16744.5 EGG09619.1 - 0.084 13.0 3.6 0.32 11.1 0.3 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger DUF836 PF05768.14 EGG09620.1 - 1.5e-08 34.9 0.1 2.1e-08 34.5 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 EGG09620.1 - 0.014 15.9 0.1 0.014 15.8 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Snf7 PF03357.21 EGG09622.1 - 1e-11 44.7 4.5 1e-11 44.7 4.5 1.3 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.14 EGG09622.1 - 0.0014 18.5 0.9 0.0021 18.0 0.9 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway FAM117 PF15388.6 EGG09622.1 - 0.1 12.0 0.3 0.11 11.9 0.3 1.1 1 0 0 1 1 1 0 Protein Family FAM117 polyprenyl_synt PF00348.17 EGG09623.1 - 3.7e-64 216.3 0.0 4.5e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF5470 PF17564.2 EGG09623.1 - 0.14 12.4 1.7 0.24 11.6 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5470) IMUP PF15761.5 EGG09623.1 - 0.85 10.3 7.8 1.4 9.7 7.8 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF4500 PF14937.6 EGG09624.1 - 0.0065 16.5 1.7 2.1 8.4 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4500) HTH_55 PF18622.1 EGG09624.1 - 0.057 13.7 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 RctB helix turn helix domain Cytochrom_B_C PF00032.17 EGG09624.1 - 0.33 11.3 6.7 5.9 7.2 2.6 2.3 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD PTSIIA_gutA PF03829.13 EGG09626.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 PTS system glucitol/sorbitol-specific IIA component RRN3 PF05327.11 EGG09627.1 - 0.16 10.5 14.9 0.26 9.8 14.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GREB1 PF15782.5 EGG09627.1 - 0.34 8.0 17.9 0.47 7.5 17.9 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PI3K_1B_p101 PF10486.9 EGG09627.1 - 3.5 5.3 25.3 5.3 4.7 25.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit WD40 PF00400.32 EGG09628.1 - 8.2e-20 70.8 7.2 3e-06 27.9 0.3 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Rhodanese_C PF12368.8 EGG09628.1 - 8.3 6.9 7.5 10 6.6 2.0 2.9 3 0 0 3 3 3 0 Rhodanase C-terminal Cep57_CLD_2 PF14197.6 EGG09633.1 - 0.0017 18.4 4.1 0.04 14.0 0.6 3.2 1 1 1 2 2 2 2 Centrosome localisation domain of PPC89 FapA PF03961.13 EGG09633.1 - 0.0039 15.9 2.4 0.0051 15.5 2.4 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A bZIP_1 PF00170.21 EGG09633.1 - 0.023 14.8 0.2 0.096 12.8 0.2 2.1 1 0 0 1 1 1 0 bZIP transcription factor Pox_F11 PF04943.12 EGG09633.1 - 0.099 11.7 0.2 0.13 11.3 0.2 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein PGBA_C PF15437.6 EGG09635.1 - 8.8 6.8 12.1 0.23 11.8 0.3 3.1 3 0 0 3 3 3 0 Plasminogen-binding protein pgbA C-terminal Pr_beta_C PF12465.8 EGG09636.1 - 0.014 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Proteasome beta subunits C terminal Topo_C_assoc PF14370.6 EGG09638.1 - 0.11 12.5 0.5 0.22 11.5 0.5 1.4 1 0 0 1 1 1 0 C-terminal topoisomerase domain VEG PF06257.11 EGG09639.1 - 0.028 14.5 0.9 0.27 11.3 0.3 2.2 2 0 0 2 2 2 0 Biofilm formation stimulator VEG P22_AR_N PF10547.9 EGG09639.1 - 0.063 13.6 1.2 1.2 9.5 0.5 2.8 1 1 0 2 2 2 0 P22_AR N-terminal domain Pkinase PF00069.25 EGG09641.1 - 1.4e-65 221.3 0.0 5.6e-65 219.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG09641.1 - 2.2e-28 99.3 0.0 3.9e-21 75.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG09641.1 - 0.00019 20.3 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGG09641.1 - 0.00021 20.7 0.1 0.018 14.4 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 EGG09641.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG09641.1 - 0.12 12.2 0.0 0.68 9.8 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family C2 PF00168.30 EGG09642.1 - 1.7e-12 47.5 0.0 1.5e-10 41.3 0.0 2.3 1 1 0 1 1 1 1 C2 domain NT-C2 PF10358.9 EGG09642.1 - 0.03 14.0 0.0 0.062 13.0 0.0 1.5 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins C2 PF00168.30 EGG09643.1 - 2.1e-09 37.6 0.1 1.8e-06 28.2 0.1 2.4 2 0 0 2 2 2 2 C2 domain DUF572 PF04502.13 EGG09645.1 - 8.7e-62 209.7 8.3 9.5e-62 209.5 8.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 EGG09645.1 - 0.017 15.2 3.6 2.2 8.4 0.1 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF866 PF05907.13 EGG09645.1 - 0.043 13.7 0.5 0.062 13.2 0.5 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zinc_ribbon_12 PF11331.8 EGG09645.1 - 0.047 13.5 0.3 6.8 6.6 0.1 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain Retrotran_gag_2 PF14223.6 EGG09647.1 - 1.2e-05 25.1 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DOG1 PF14144.6 EGG09647.1 - 0.066 13.4 0.0 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 Seed dormancy control Adap_comp_sub PF00928.21 EGG09649.1 - 8.1e-37 127.0 0.0 9.2e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family MAM PF00629.23 EGG09649.1 - 0.11 12.4 1.9 0.16 11.9 0.2 1.9 2 0 0 2 2 2 0 MAM domain, meprin/A5/mu TSKS PF15358.6 EGG09652.1 - 0.013 13.9 0.7 0.013 13.9 0.7 1.7 2 1 0 2 2 2 0 Testis-specific serine kinase substrate Bud13 PF09736.9 EGG09653.1 - 2.7e-06 27.8 0.0 3.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex Hep_59 PF07052.11 EGG09654.1 - 1.5e-30 106.0 0.4 1.5e-30 106.0 0.4 3.5 3 2 1 4 4 4 1 Hepatocellular carcinoma-associated antigen 59 Cep57_CLD_2 PF14197.6 EGG09654.1 - 0.13 12.3 0.3 0.13 12.3 0.3 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Fer4 PF00037.27 EGG09655.1 - 2.7e-14 52.3 15.9 1.7e-08 34.0 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGG09655.1 - 7.5e-13 48.9 9.1 1.1e-12 48.3 9.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGG09655.1 - 2.1e-11 44.6 7.0 1.7e-05 25.7 0.6 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EGG09655.1 - 1.3e-10 41.2 31.5 1.5e-06 28.2 11.8 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGG09655.1 - 3e-09 36.8 21.1 2.4e-06 27.6 12.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGG09655.1 - 3.9e-09 36.8 3.1 0.00012 22.5 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGG09655.1 - 4e-09 36.5 9.0 8.4e-09 35.5 9.1 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EGG09655.1 - 2.2e-07 30.6 11.1 0.0019 18.2 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 EGG09655.1 - 3.3e-07 30.1 17.0 0.00022 21.1 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EGG09655.1 - 1.5e-06 28.2 10.6 0.00015 22.0 1.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EGG09655.1 - 8.1e-05 23.1 11.3 0.0081 16.7 12.1 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EGG09655.1 - 0.00041 20.5 4.7 0.14 12.4 0.5 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_13 PF13370.6 EGG09655.1 - 0.00092 19.7 10.9 0.19 12.3 0.5 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EGG09655.1 - 0.0048 17.1 8.0 0.9 9.8 8.0 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 EGG09655.1 - 0.075 14.0 16.3 0.2 12.7 4.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EGG09655.1 - 0.18 12.7 11.7 1.1 10.1 1.6 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain ETF_QO PF05187.13 EGG09655.1 - 0.36 11.0 5.6 1 9.5 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Chorismate_bind PF00425.18 EGG09656.1 - 2.7e-76 256.6 0.0 4e-76 256.0 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EGG09656.1 - 5e-27 94.9 0.0 6.1e-24 84.8 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EGG09656.1 - 8.8e-11 42.2 0.0 3.1e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EGG09656.1 - 4.8e-10 39.5 0.0 1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 FCP1_C PF09309.10 EGG09660.1 - 1.3 8.8 12.3 1.7 8.4 12.3 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Presenilin PF01080.17 EGG09660.1 - 1.9 7.2 7.2 2 7.1 7.2 1.0 1 0 0 1 1 1 0 Presenilin DUF4604 PF15377.6 EGG09660.1 - 3.3 8.1 15.2 4.2 7.8 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RNase_H2_suC PF08615.11 EGG09660.1 - 7.5 6.7 10.6 54 4.0 10.6 2.0 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) 2Fe-2S_thioredx PF01257.19 EGG09661.1 - 7.3e-59 197.8 0.1 9e-59 197.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.11 EGG09661.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) La_HTH_kDCL PF18177.1 EGG09663.1 - 0.088 13.1 0.1 0.34 11.2 0.1 2.0 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain DUF702 PF05142.12 EGG09665.1 - 0.32 11.5 7.6 0.64 10.5 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Alpha_kinase PF02816.18 EGG09666.1 - 0.00013 22.2 0.1 0.00019 21.6 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family Parathyroid PF01279.17 EGG09667.1 - 0.0013 19.3 2.6 0.21 12.2 0.2 3.6 1 1 1 2 2 2 2 Parathyroid hormone family VCBS PF13517.6 EGG09668.1 - 6.4e-23 81.1 9.9 1e-06 29.2 0.0 5.1 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGG09668.1 - 4.4e-06 26.7 11.6 0.024 14.8 0.1 5.7 6 0 0 6 6 6 2 FG-GAP repeat Itfg2 PF15907.5 EGG09668.1 - 0.04 13.0 0.3 7.7 5.5 0.0 2.9 3 1 0 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 PliI PF16743.5 EGG09668.1 - 0.059 13.1 0.0 42 3.9 0.0 3.5 3 0 0 3 3 3 0 Periplasmic lysozyme inhibitor of I-type lysozyme Dockerin_1 PF00404.18 EGG09668.1 - 0.11 12.6 0.1 5.4 7.3 0.0 3.2 3 0 0 3 3 3 0 Dockerin type I domain GCOM2 PF15328.6 EGG09669.1 - 0.023 15.1 2.5 0.051 13.9 2.5 1.6 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 PDEase_I_N PF08499.12 EGG09669.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Vac7 PF12751.7 EGG09669.1 - 0.18 11.2 2.0 0.29 10.5 2.0 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 WD40 PF00400.32 EGG09671.1 - 3.1e-11 43.6 18.4 0.022 15.6 0.4 6.8 6 1 0 6 6 6 4 WD domain, G-beta repeat Mei5 PF10376.9 EGG09671.1 - 0.045 13.6 2.4 0.086 12.7 2.4 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein PQQ_3 PF13570.6 EGG09671.1 - 0.046 14.2 0.0 3.3 8.3 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain ANAPC4_WD40 PF12894.7 EGG09671.1 - 0.047 14.0 0.1 3.9 7.8 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L5_C PF00673.21 EGG09675.1 - 2.3e-22 79.0 0.0 3.8e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGG09675.1 - 1.2e-20 73.5 0.0 1.9e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 MTBP_C PF14920.6 EGG09676.1 - 0.058 13.1 5.8 0.07 12.9 5.8 1.1 1 0 0 1 1 1 0 MDM2-binding Methyltransf_16 PF10294.9 EGG09677.1 - 1.2e-14 54.4 0.0 7.6e-13 48.6 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 EGG09677.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DNA_ligase_A_M PF01068.21 EGG09678.1 - 3e-35 121.7 1.4 1e-32 113.5 0.1 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGG09678.1 - 3.9e-35 121.7 0.0 1.1e-34 120.3 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGG09678.1 - 4e-19 69.0 0.0 9.6e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EGG09678.1 - 0.091 13.1 0.0 1.4 9.2 0.0 2.2 1 1 0 1 1 1 0 RNA ligase Pkinase PF00069.25 EGG09679.1 - 1.4e-72 244.3 0.0 1.6e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG09679.1 - 8.4e-47 159.6 0.0 1.1e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG09679.1 - 4.1e-06 25.8 0.0 6.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGG09679.1 - 9.7e-06 25.1 0.0 0.039 13.3 0.0 2.4 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 EGG09679.1 - 0.13 12.2 0.0 18 5.1 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Spc7 PF08317.11 EGG09681.1 - 0.004 16.1 2.3 0.0065 15.4 2.3 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Macoilin PF09726.9 EGG09681.1 - 0.011 14.3 0.3 0.014 14.0 0.3 1.1 1 0 0 1 1 1 0 Macoilin family Borrelia_REV PF03978.13 EGG09681.1 - 0.14 12.1 0.8 0.24 11.4 0.8 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Glyco_tranf_2_4 PF13704.6 EGG09682.1 - 0.064 13.8 0.1 0.39 11.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Alpha_kinase PF02816.18 EGG09684.1 - 2.9e-30 105.8 1.1 5.6e-30 104.8 1.1 1.5 1 0 0 1 1 1 1 Alpha-kinase family Prim_Zn_Ribbon PF08273.12 EGG09684.1 - 0.13 12.5 0.3 0.45 10.8 0.2 1.9 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Rab5-bind PF09311.11 EGG09685.1 - 0.054 12.9 1.2 0.085 12.2 1.2 1.2 1 0 0 1 1 1 0 Rabaptin-like protein Blo-t-5 PF11642.8 EGG09687.1 - 0.0074 16.2 1.7 0.0094 15.9 1.4 1.4 1 1 0 1 1 1 1 Mite allergen Blo t 5 Thiol_cytolysin PF01289.19 EGG09687.1 - 0.036 13.0 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 Thiol-activated cytolysin DUF2972 PF11186.8 EGG09687.1 - 0.065 13.1 4.9 0.28 11.1 4.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) AvrM-A PF18241.1 EGG09687.1 - 0.067 13.6 1.4 0.098 13.1 1.4 1.3 1 1 0 1 1 1 0 Flax-rust effector AvrM-A Thiol_cytolysin PF01289.19 EGG09688.1 - 0.036 13.0 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 Thiol-activated cytolysin Blo-t-5 PF11642.8 EGG09688.1 - 0.041 13.9 1.6 0.053 13.5 1.4 1.4 1 1 0 1 1 1 0 Mite allergen Blo t 5 AvrM-A PF18241.1 EGG09688.1 - 0.044 14.2 0.8 0.056 13.9 0.8 1.2 1 0 0 1 1 1 0 Flax-rust effector AvrM-A DUF2972 PF11186.8 EGG09688.1 - 0.067 13.1 5.0 0.27 11.1 5.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) DUF501 PF04417.12 EGG09688.1 - 0.26 11.1 1.8 0.59 9.9 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF501) ABC_membrane_2 PF06472.15 EGG09689.1 - 2.4e-09 37.0 1.1 2.7e-09 36.9 1.1 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 EBV-NA3 PF05009.12 EGG09694.1 - 0.16 11.5 0.5 0.23 11.0 0.5 1.3 1 1 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) FlxA PF14282.6 EGG09695.1 - 0.05 13.6 0.8 3.7 7.6 0.3 2.3 1 1 1 2 2 2 0 FlxA-like protein Lzipper-MIP1 PF14389.6 EGG09695.1 - 0.06 13.7 1.6 0.093 13.0 0.5 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Cnn_1N PF07989.11 EGG09695.1 - 0.063 13.4 1.8 0.32 11.2 0.3 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 HrpB_C PF08482.10 EGG09695.1 - 0.092 13.2 0.1 0.17 12.3 0.1 1.4 1 1 0 1 1 1 0 ATP-dependent helicase C-terminal DivIC PF04977.15 EGG09695.1 - 0.11 12.3 1.4 4.7 7.1 0.1 2.6 2 1 1 3 3 3 0 Septum formation initiator DUF2340 PF10209.9 EGG09695.1 - 0.11 12.9 1.4 0.18 12.3 1.4 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) YscO PF07321.12 EGG09695.1 - 0.13 12.2 1.9 0.38 10.7 0.3 2.0 2 1 0 2 2 2 0 Type III secretion protein YscO DUF4404 PF14357.6 EGG09695.1 - 0.22 12.2 3.5 3.6 8.3 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) LRR_4 PF12799.7 EGG09700.1 - 0.041 14.3 8.8 0.098 13.1 2.4 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 EGG09700.1 - 0.065 13.9 2.9 15 6.5 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat PUFD PF16553.5 EGG09702.1 - 0.057 13.5 2.5 0.065 13.4 0.7 2.0 2 0 0 2 2 2 0 BCORL-PCGF1-binding domain DUF1515 PF07439.11 EGG09702.1 - 0.074 13.1 0.6 0.17 12.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) HMG_box PF00505.19 EGG09702.1 - 0.31 11.5 3.8 14 6.2 0.2 3.0 3 0 0 3 3 3 0 HMG (high mobility group) box DUF3330 PF11809.8 EGG09703.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) UQ_con PF00179.26 EGG09705.1 - 1e-42 145.1 0.0 1.1e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGG09705.1 - 0.01 15.5 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 EGG09705.1 - 0.021 15.1 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain Cu_bind_like PF02298.17 EGG09707.1 - 0.036 14.1 0.2 0.15 12.1 0.2 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain BLACT_WH PF17778.1 EGG09708.1 - 2.1e-14 53.2 0.1 3.4e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 EGG09708.1 - 1.1e-11 45.1 0.3 1.5e-09 38.2 0.2 2.9 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGG09708.1 - 0.00085 18.9 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HECT PF00632.25 EGG09709.1 - 2e-93 313.2 0.0 2.6e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EGG09709.1 - 1.8e-35 120.7 15.6 1.2e-12 47.7 1.9 3.9 3 0 0 3 3 3 3 WW domain C2 PF00168.30 EGG09709.1 - 2e-20 73.0 0.2 4.2e-20 71.9 0.2 1.6 1 0 0 1 1 1 1 C2 domain DUF155 PF02582.14 EGG09710.1 - 2.5e-39 135.2 0.0 3.6e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PI3_PI4_kinase PF00454.27 EGG09713.1 - 8.9e-32 110.9 0.1 1e-28 100.8 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGG09713.1 - 2.2e-22 79.4 0.0 5.9e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) FA_hydroxylase PF04116.13 EGG09714.1 - 2.8e-21 76.2 14.0 2.8e-21 76.2 14.0 2.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily CAP_N PF01213.19 EGG09715.1 - 5.7e-110 367.7 0.0 5.7e-110 367.7 0.0 1.5 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EGG09715.1 - 7e-63 210.9 6.0 9.4e-63 210.5 6.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EGG09715.1 - 0.016 14.9 0.9 0.035 13.8 0.9 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor C BURP PF03181.15 EGG09715.1 - 0.17 11.4 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 BURP domain DUF3506 PF12014.8 EGG09719.1 - 1e-10 41.8 0.0 1.4e-08 34.9 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) RRM_1 PF00076.22 EGG09720.1 - 1.3e-17 63.4 0.2 2e-17 62.8 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG09720.1 - 6.2e-07 29.1 0.0 7.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4604 PF15377.6 EGG09723.1 - 0.27 11.6 7.1 0.025 15.0 2.9 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Cellulase PF00150.18 EGG09724.1 - 6.7e-13 48.7 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LAT2 PF15703.5 EGG09725.1 - 0.0016 18.4 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 Linker for activation of T-cells family member 2 HMG_box PF00505.19 EGG09726.1 - 0.041 14.3 0.1 0.84 10.1 0.0 2.7 2 0 0 2 2 2 0 HMG (high mobility group) box alpha-hel2 PF14456.6 EGG09726.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 Glyco_transf_15 PF01793.16 EGG09728.1 - 1.7e-82 277.3 13.1 3.7e-78 263.0 10.2 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase DUF2129 PF09902.9 EGG09728.1 - 0.028 14.5 0.1 0.069 13.2 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) ParBc PF02195.18 EGG09730.1 - 0.055 13.8 0.0 0.25 11.7 0.0 2.0 1 1 1 2 2 2 0 ParB-like nuclease domain SAP PF02037.27 EGG09733.1 - 0.015 15.0 0.7 0.029 14.1 0.7 1.4 1 0 0 1 1 1 0 SAP domain DUF1744 PF08490.12 EGG09733.1 - 0.14 10.7 1.1 0.23 10.0 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Merozoite_SPAM PF07133.11 EGG09733.1 - 0.48 10.4 47.2 0.04 13.9 42.2 1.7 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) DUF2254 PF10011.9 EGG09733.1 - 1.8 7.3 4.0 2.6 6.8 4.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Trypan_PARP PF05887.11 EGG09733.1 - 4.5 7.2 23.8 9.7 6.2 23.8 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MIF4G_like_2 PF09090.11 EGG09733.1 - 4.8 6.6 13.8 8.4 5.8 13.8 1.4 1 0 0 1 1 1 0 MIF4G like Paf1 PF03985.13 EGG09733.1 - 9.3 5.1 27.2 19 4.1 27.2 1.5 1 0 0 1 1 1 0 Paf1 Pkinase PF00069.25 EGG09734.1 - 2.9e-44 151.4 0.0 3.6e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG09734.1 - 7.6e-44 149.9 0.0 8.7e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG09734.1 - 0.0042 17.0 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG09734.1 - 0.028 13.4 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Acyl-CoA_dh_1 PF00441.24 EGG09736.1 - 8.1e-48 162.4 0.3 1.3e-47 161.8 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGG09736.1 - 1e-28 99.4 0.4 2.8e-28 98.0 0.4 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGG09736.1 - 7.8e-24 84.5 0.0 1.5e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGG09736.1 - 1.1e-15 58.1 0.1 1.7e-15 57.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EGG09736.1 - 0.0026 17.5 0.1 0.0059 16.3 0.1 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Phage_TTP_11 PF16460.5 EGG09736.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Phage tail tube, TTP, lambda-like Cpn60_TCP1 PF00118.24 EGG09737.1 - 5.4e-149 497.0 16.1 6.4e-149 496.7 16.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GRDP-like PF07173.12 EGG09738.1 - 4.8e-14 53.2 3.8 2e-12 47.9 0.0 3.7 3 0 0 3 3 3 1 Glycine-rich domain-containing protein-like Herpes_UL25 PF01499.16 EGG09738.1 - 0.055 12.0 3.7 0.093 11.2 3.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family BCDHK_Adom3 PF10436.9 EGG09738.1 - 0.06 13.2 1.5 0.15 11.9 1.5 1.6 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Methyltransf_16 PF10294.9 EGG09739.1 - 1.5e-19 70.4 0.0 2e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGG09739.1 - 0.003 17.4 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG09739.1 - 0.032 14.9 0.0 0.084 13.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGG09739.1 - 0.087 13.6 0.1 0.31 11.8 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain MethyltransfD12 PF02086.15 EGG09739.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.13 EGG09739.1 - 0.18 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 6PGD PF00393.19 EGG09740.1 - 1.7e-126 421.5 0.0 2.2e-126 421.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGG09740.1 - 2e-49 167.8 0.0 2.8e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGG09740.1 - 0.029 15.0 0.1 0.049 14.2 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 EGG09740.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ApbA PF02558.16 EGG09740.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TFIID-18kDa PF02269.16 EGG09741.1 - 2.4e-30 104.4 0.1 8.6e-30 102.6 0.1 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit GP67 PF17634.2 EGG09741.1 - 0.21 12.0 6.9 0.058 13.8 2.5 2.3 2 0 0 2 2 2 0 Gene product 67 Abhydrolase_1 PF00561.20 EGG09742.1 - 2e-38 132.5 0.0 1.5e-37 129.7 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGG09742.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ndc1_Nup PF09531.10 EGG09745.1 - 9.4e-113 378.0 6.5 1.1e-112 377.7 6.5 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup MBOAT_2 PF13813.6 EGG09747.1 - 1.5e-10 41.2 2.4 3e-10 40.2 2.4 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SpoVR PF04293.13 EGG09748.1 - 0.086 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 SpoVR like protein ECH_1 PF00378.20 EGG09754.1 - 1.2e-83 280.3 0.0 1.4e-83 280.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGG09754.1 - 6.9e-37 127.7 0.2 1e-31 110.7 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EGG09754.1 - 0.00035 20.6 0.2 0.041 13.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 DUF3813 PF12758.7 EGG09754.1 - 0.046 14.0 0.4 0.14 12.5 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Peptidase_C31 PF05410.13 EGG09754.1 - 0.061 13.4 0.0 16 5.7 0.0 2.3 2 0 0 2 2 2 0 Porcine arterivirus-type cysteine proteinase alpha Cellulase PF00150.18 EGG09755.1 - 8.3e-15 55.0 0.1 1.5e-14 54.1 0.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-C3HC4_3 PF13920.6 EGG09756.1 - 0.11 12.4 11.4 0.21 11.5 11.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) KDZ PF18758.1 EGG09757.1 - 9.1e-56 189.0 0.1 1.7e-55 188.1 0.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGG09757.1 - 6.7e-22 77.6 0.5 1.3e-21 76.6 0.5 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG09757.1 - 5e-07 29.9 0.1 1.1e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases GvpK PF05121.12 EGG09757.1 - 0.79 9.8 7.5 0.19 11.8 2.2 2.7 3 0 0 3 3 3 0 Gas vesicle protein K Fil_haemagg_2 PF13332.6 EGG09760.1 - 0.087 12.9 5.4 0.47 10.6 5.4 1.8 1 1 0 1 1 1 0 Hemagglutinin repeat SRP19 PF01922.17 EGG09763.1 - 0.06 14.3 0.3 2.7 9.0 0.1 2.4 2 1 0 2 2 2 0 SRP19 protein TRAM_LAG1_CLN8 PF03798.16 EGG09764.1 - 4.2e-40 137.6 21.2 4.2e-40 137.6 21.2 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EGG09764.1 - 1.3e-12 47.2 0.3 1.1e-11 44.2 0.0 2.6 2 0 0 2 2 2 1 TRAM1-like protein KRTAP7 PF15034.6 EGG09764.1 - 0.036 15.0 0.1 0.076 14.0 0.1 1.5 1 0 0 1 1 1 0 KRTAP type 7 family EI24 PF07264.11 EGG09765.1 - 1.5e-19 70.9 8.7 2.2e-19 70.4 8.7 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) E1-E2_ATPase PF00122.20 EGG09767.1 - 2.9e-54 183.3 4.3 2.9e-54 183.3 4.3 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGG09767.1 - 4.7e-45 153.5 5.9 4.7e-45 153.5 5.9 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGG09767.1 - 2.4e-24 86.8 0.5 2.4e-24 86.8 0.5 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG09767.1 - 4.7e-20 71.5 0.1 1.3e-19 70.1 0.1 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGG09767.1 - 4e-16 58.4 0.2 4e-16 58.4 0.2 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG09767.1 - 1.9e-07 31.1 3.7 8.8e-06 25.6 0.6 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG09767.1 - 7.2e-06 26.5 0.0 2.1e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GHL6 PF14871.6 EGG09767.1 - 0.026 14.6 0.4 37 4.5 0.0 3.4 2 1 0 3 3 3 0 Hypothetical glycosyl hydrolase 6 TraL PF07178.11 EGG09767.1 - 0.91 10.0 4.5 3.9 8.0 0.1 3.2 3 0 0 3 3 3 0 TraL protein Amidohydro_2 PF04909.14 EGG09768.1 - 1e-13 51.8 0.0 1.4e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase MRP-S28 PF10213.9 EGG09769.1 - 1.6e-19 70.6 0.0 2.6e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein UFD1 PF03152.14 EGG09771.1 - 5.2e-64 214.9 0.0 6.5e-64 214.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Abhydrolase_1 PF00561.20 EGG09772.1 - 9.3e-08 32.0 0.0 1.1e-05 25.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold SCAMP PF04144.13 EGG09773.1 - 8.7e-52 175.9 9.0 1e-51 175.7 9.0 1.1 1 0 0 1 1 1 1 SCAMP family Peptidase_U4 PF03419.13 EGG09773.1 - 0.29 10.4 6.6 0.41 9.9 6.6 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA TIP120 PF08623.10 EGG09774.1 - 6.5e-58 195.2 3.7 2.2e-56 190.3 0.2 4.4 4 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EGG09774.1 - 8e-14 51.8 6.6 0.0028 18.0 0.0 8.6 8 2 1 9 9 9 3 HEAT repeats HEAT PF02985.22 EGG09774.1 - 1.5e-12 46.6 18.0 0.042 14.1 0.0 11.6 13 0 0 13 13 10 4 HEAT repeat HEAT_EZ PF13513.6 EGG09774.1 - 5.3e-12 46.0 9.6 0.33 11.5 0.0 10.2 11 0 0 11 11 9 2 HEAT-like repeat Cnd1 PF12717.7 EGG09774.1 - 1.8e-08 34.6 7.4 0.011 15.7 0.1 6.2 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EGG09774.1 - 0.00025 21.2 7.3 0.4 10.9 0.0 6.6 7 1 0 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EGG09774.1 - 0.0011 18.6 3.3 0.22 11.1 0.0 4.9 5 1 0 6 6 6 1 CLASP N terminal API5 PF05918.11 EGG09774.1 - 0.014 14.2 2.4 0.071 11.9 0.2 2.8 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) V-ATPase_H_C PF11698.8 EGG09774.1 - 0.021 15.0 2.5 1.8 8.7 0.0 4.8 5 0 0 5 5 5 0 V-ATPase subunit H VHS PF00790.19 EGG09774.1 - 0.021 14.7 0.3 0.34 10.8 0.0 3.3 2 0 0 2 2 2 0 VHS domain DUF4042 PF13251.6 EGG09774.1 - 0.036 13.8 9.0 4 7.1 0.0 6.3 6 2 1 7 7 7 0 Domain of unknown function (DUF4042) Proteasom_PSMB PF10508.9 EGG09774.1 - 0.04 12.4 0.0 0.04 12.4 0.0 4.2 4 1 1 6 6 6 0 Proteasome non-ATPase 26S subunit Tti2 PF10521.9 EGG09774.1 - 0.05 13.1 3.3 7.3 6.0 0.0 4.4 5 1 0 5 5 5 0 Tti2 family FPL PF09758.9 EGG09774.1 - 0.066 13.2 0.2 4.7 7.2 0.0 3.6 3 0 0 3 3 3 0 Uncharacterised conserved protein Urb2 PF10441.9 EGG09774.1 - 0.2 11.6 0.0 0.2 11.6 0.0 3.3 3 1 0 4 4 4 0 Urb2/Npa2 family Arm PF00514.23 EGG09774.1 - 0.22 11.6 9.6 16 5.7 0.0 5.9 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 EGG09774.1 - 1.1 8.4 23.8 0.14 11.3 2.1 6.9 7 2 1 8 8 8 0 RNAPII transcription regulator C-terminal V-ATPase_H_N PF03224.14 EGG09774.1 - 2.1 7.6 9.2 0.76 9.0 1.0 3.7 3 2 0 3 3 3 0 V-ATPase subunit H ParcG PF10274.9 EGG09774.1 - 5.9 7.0 6.8 42 4.2 0.3 4.4 5 1 1 6 6 6 0 Parkin co-regulated protein Sec66 PF09802.9 EGG09775.1 - 8e-23 80.9 0.1 1e-22 80.6 0.1 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SAS-6_N PF16531.5 EGG09775.1 - 0.013 16.0 0.6 0.024 15.2 0.6 1.4 1 0 0 1 1 1 0 Centriolar protein SAS N-terminal Glyco_transf_18 PF15024.6 EGG09777.1 - 1.3e-09 37.2 0.0 5.6e-09 35.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 18 Glyco_transf_18 PF15024.6 EGG09779.1 - 2e-13 49.8 0.0 2.4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 OHCU_decarbox PF09349.10 EGG09779.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 OHCU decarboxylase WD40 PF00400.32 EGG09780.1 - 6.8e-17 61.5 16.3 0.00032 21.4 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Frankia_peptide PF14407.6 EGG09780.1 - 0.024 14.6 0.3 0.096 12.7 0.3 2.0 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Vfa1 PF08432.10 EGG09780.1 - 3.8 7.8 10.0 3.5 7.9 5.0 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PAC2 PF09754.9 EGG09782.1 - 1.1e-21 77.8 0.0 1.5e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 PAC2 family Peptidase_S28 PF05577.12 EGG09784.1 - 1.1e-47 162.8 0.1 2.8e-46 158.2 0.1 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Ras PF00071.22 EGG09785.1 - 3.3e-49 166.6 0.0 3.8e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG09785.1 - 3.8e-20 72.3 0.0 5.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG09785.1 - 1.2e-05 24.9 0.0 2.6e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGG09785.1 - 0.018 14.9 0.0 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EGG09785.1 - 0.09 13.0 0.1 1 9.7 0.0 2.3 2 1 1 3 3 3 0 AAA domain GTP_EFTU PF00009.27 EGG09785.1 - 0.19 11.2 0.1 0.37 10.3 0.0 1.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Peptidase_S8 PF00082.22 EGG09786.1 - 1e-35 123.4 0.3 1.7e-35 122.8 0.3 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EGG09786.1 - 5.3e-26 90.5 0.3 1.7e-25 88.8 0.1 2.1 2 0 0 2 2 2 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 EGG09786.1 - 0.15 12.5 0.3 0.73 10.3 0.0 2.2 2 0 0 2 2 2 0 N-terminal of Subtilase family Hist_deacetyl PF00850.19 EGG09787.1 - 3.4e-85 286.2 0.0 4.3e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain 6PF2K PF01591.18 EGG09789.1 - 1.7e-69 233.5 0.4 1.2e-65 221.0 0.1 2.2 1 1 1 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGG09789.1 - 1.5e-37 129.2 0.0 2.8e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGG09789.1 - 1.3e-06 28.6 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Methyltransf_32 PF13679.6 EGG09789.1 - 0.0058 16.6 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain KTI12 PF08433.10 EGG09789.1 - 0.023 14.1 0.0 0.043 13.3 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EGG09789.1 - 0.076 12.3 0.0 0.2 10.9 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin GBP PF02263.19 EGG09789.1 - 0.097 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Vac_ImportDeg PF09783.9 EGG09790.1 - 8.4e-39 133.0 0.7 3.2e-38 131.1 0.7 1.8 1 1 0 1 1 1 1 Vacuolar import and degradation protein SPAR_C PF11881.8 EGG09790.1 - 0.026 14.4 0.1 0.026 14.4 0.1 1.6 2 0 0 2 2 2 0 C-terminal domain of SPAR protein CxC1 PF18802.1 EGG09791.1 - 2e-34 117.9 0.1 4.5e-34 116.7 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG09791.1 - 8.9e-06 25.8 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG09791.1 - 0.0039 17.0 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases RITA PF17066.5 EGG09795.1 - 0.14 11.7 4.9 0.068 12.7 2.9 1.3 1 1 0 1 1 1 0 RBPJ-interacting and tubulin associated protein GYF PF02213.16 EGG09796.1 - 6.9e-05 22.4 0.2 0.00016 21.3 0.2 1.6 1 0 0 1 1 1 1 GYF domain DUF2326 PF10088.9 EGG09796.1 - 0.069 12.9 0.5 0.22 11.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) PBP PF01161.20 EGG09800.1 - 3.5e-09 37.1 0.0 6.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF4726 PF15855.5 EGG09801.1 - 0.0028 17.9 1.1 0.0094 16.1 1.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4726) Mago_nashi PF02792.14 EGG09804.1 - 4.8e-65 218.0 0.4 5.6e-65 217.8 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein F-box-like PF12937.7 EGG09805.1 - 0.0016 18.3 0.3 0.0077 16.1 0.0 2.4 2 0 0 2 2 2 1 F-box-like HNH_4 PF13395.6 EGG09805.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 HNH endonuclease Asp-B-Hydro_N PF05279.11 EGG09806.1 - 3 7.8 22.6 4.5 7.3 22.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region EKR PF10371.9 EGG09807.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF43 PF01861.16 EGG09810.1 - 0.022 14.0 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain TPR_2 PF07719.17 EGG09811.1 - 0.0035 17.4 0.5 1 9.6 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat PPR PF01535.20 EGG09811.1 - 0.073 13.3 0.1 3.3 8.2 0.1 2.6 2 0 0 2 2 2 0 PPR repeat TPR_15 PF13429.6 EGG09811.1 - 0.13 11.5 0.0 0.47 9.6 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat GHL13 PF14883.6 EGG09811.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 Y_phosphatase2 PF03162.13 EGG09814.1 - 1.8e-35 121.9 0.0 2e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGG09814.1 - 2.9e-06 27.4 0.0 5.2e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EGG09814.1 - 0.00012 21.9 0.0 0.00012 21.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG09814.1 - 0.00063 19.4 0.0 0.00067 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RRM_1 PF00076.22 EGG09816.1 - 2.2e-15 56.2 0.0 3.6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG09816.1 - 0.007 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif EKLF_TAD1 PF16832.5 EGG09817.1 - 1.6 8.7 4.8 3.4 7.6 4.8 1.5 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Anillin_N PF16018.5 EGG09817.1 - 7 7.3 11.2 2.7 8.7 0.4 4.1 3 1 0 3 3 3 0 Anillin N-terminus Helicase_C PF00271.31 EGG09818.1 - 2.4e-15 56.8 0.0 5.6e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG09818.1 - 4.4e-06 26.6 0.0 1.2e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase CAF1A PF12253.8 EGG09819.1 - 1.3e-23 82.9 1.8 4.6e-23 81.2 1.8 2.0 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A DUF5105 PF17118.5 EGG09819.1 - 0.38 10.5 7.5 0.068 13.0 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5105) Hormone_recep PF00104.30 EGG09820.1 - 0.61 9.6 2.1 1.9 8.0 2.1 1.6 1 1 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor DUF4440 PF14534.6 EGG09821.1 - 0.0078 16.6 0.0 0.0098 16.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) TMEM252 PF15664.5 EGG09821.1 - 0.022 14.5 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 252 family CIDE-N PF02017.15 EGG09821.1 - 0.033 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 CIDE-N domain MCR_beta_N PF02783.15 EGG09823.1 - 0.0099 15.5 0.2 0.19 11.3 0.1 2.1 2 0 0 2 2 2 1 Methyl-coenzyme M reductase beta subunit, N-terminal domain XhlA PF10779.9 EGG09823.1 - 0.032 14.4 3.3 3.3 8.0 0.2 2.4 2 0 0 2 2 2 0 Haemolysin XhlA baeRF_family2 PF18844.1 EGG09823.1 - 0.056 13.5 3.9 3.1 7.9 0.4 2.3 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 SipA_VBS PF17985.1 EGG09823.1 - 0.056 13.3 8.4 1 9.3 0.6 2.4 2 0 0 2 2 2 0 SipA vinculin binding site RHH_1 PF01402.21 EGG09823.1 - 0.12 12.4 8.9 1.7 8.7 0.3 2.8 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family DUF3486 PF11985.8 EGG09823.1 - 0.15 12.5 11.6 1.7 9.0 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) DUF3782 PF12644.7 EGG09823.1 - 0.16 12.1 1.3 18 5.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) MalM PF07148.12 EGG09823.1 - 0.17 11.7 0.4 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Maltose operon periplasmic protein precursor (MalM) Rotamase_2 PF13145.6 EGG09823.1 - 0.17 12.7 4.9 1.5 9.7 0.4 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain DUF4312 PF14189.6 EGG09823.1 - 0.28 11.2 1.6 18 5.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4312) TEX13 PF15186.6 EGG09823.1 - 1.6 8.4 4.9 12 5.6 0.5 2.2 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Histone_HNS PF00816.21 EGG09823.1 - 1.8 9.4 10.5 2.5 9.0 1.3 2.2 2 0 0 2 2 2 0 H-NS histone family Apidaecin PF00807.17 EGG09823.1 - 2 8.6 9.6 4.1 7.6 2.0 2.8 2 0 0 2 2 2 0 Apidaecin HTH_11 PF08279.12 EGG09824.1 - 0.045 13.7 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 HTH domain DUF3776 PF12618.8 EGG09825.1 - 0.14 12.7 2.3 0.24 12.0 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) Glyco_hydro_28 PF00295.17 EGG09826.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 Oxidored_FMN PF00724.20 EGG09827.1 - 1.7e-29 103.2 0.0 3.1e-29 102.3 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Alpha_kinase PF02816.18 EGG09828.1 - 7.5e-06 26.2 0.7 1.3e-05 25.5 0.7 1.2 1 0 0 1 1 1 1 Alpha-kinase family DUF2315 PF10231.9 EGG09829.1 - 1.9e-16 60.2 2.1 6.2e-16 58.6 2.1 1.8 1 1 0 1 1 1 1 Apoptogenic protein 1 Glycos_transf_1 PF00534.20 EGG09830.1 - 1.4e-22 80.0 0.0 6.6e-22 77.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGG09830.1 - 1.9e-18 67.1 0.0 3.2e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EGG09830.1 - 5e-09 36.7 0.0 1.5e-08 35.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGG09830.1 - 5.9e-08 33.3 0.0 1.2e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGG09830.1 - 4.9e-06 26.8 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 EGG09830.1 - 0.0018 18.4 0.0 0.0047 17.0 0.0 1.7 1 1 0 1 1 1 1 ALG11 mannosyltransferase N-terminus CoxIIa PF08113.11 EGG09830.1 - 0.36 10.7 3.8 0.87 9.5 3.8 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family VRR_NUC PF08774.11 EGG09831.1 - 4.3e-20 71.8 0.0 1.4e-19 70.2 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain DUF4329 PF14220.6 EGG09831.1 - 0.0052 16.8 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4329) TAF PF02969.17 EGG09832.1 - 1.6e-28 98.7 0.2 5e-28 97.1 0.1 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 EGG09832.1 - 3.9e-18 65.6 0.1 8.4e-18 64.5 0.1 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 EGG09832.1 - 0.0017 18.7 0.2 0.0017 18.7 0.2 3.2 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 RuvB_N PF05496.12 EGG09832.1 - 0.018 14.8 0.1 0.058 13.1 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TP_methylase PF00590.20 EGG09832.1 - 0.023 14.7 0.3 0.43 10.5 0.0 2.6 2 1 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases CBFD_NFYB_HMF PF00808.23 EGG09832.1 - 0.086 13.1 0.3 0.86 9.9 0.1 2.5 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HEAT_EZ PF13513.6 EGG09832.1 - 0.16 12.5 0.3 12 6.5 0.1 3.6 2 1 1 3 3 3 0 HEAT-like repeat ECM1 PF05782.11 EGG09832.1 - 9.2 5.1 8.1 13 4.5 8.1 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Methyltransf_10 PF05971.12 EGG09833.1 - 1.2e-42 146.3 0.0 1.4e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase PrmA PF06325.13 EGG09833.1 - 0.00038 20.0 0.0 0.0005 19.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGG09833.1 - 0.003 17.1 0.0 0.0055 16.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EGG09833.1 - 0.0032 17.4 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EGG09833.1 - 0.021 13.8 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TrmK PF04816.12 EGG09833.1 - 0.03 13.8 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_10 PF05971.12 EGG09834.1 - 3.6e-14 52.8 0.2 4.8e-14 52.4 0.2 1.2 1 0 0 1 1 1 1 RNA methyltransferase Emaravirus_P4 PF16505.5 EGG09834.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily Asp PF00026.23 EGG09835.1 - 1.9e-67 227.9 0.9 2.4e-67 227.6 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG09835.1 - 5.3e-13 49.6 1.7 5.6e-07 30.0 0.1 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGG09835.1 - 2.6e-05 24.8 0.1 0.026 15.2 0.0 3.2 2 1 0 2 2 2 2 Aspartyl protease AAA PF00004.29 EGG09836.1 - 1.8e-17 64.0 0.0 3.5e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EGG09836.1 - 1.1e-13 51.4 0.1 3.3e-13 49.8 0.1 1.9 1 1 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EGG09836.1 - 1.7e-13 50.6 0.1 5e-11 42.6 0.0 2.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 EGG09836.1 - 6.8e-06 26.4 0.1 0.0014 19.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGG09836.1 - 2.7e-05 24.6 0.0 0.00015 22.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 EGG09836.1 - 4.4e-05 23.7 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain Rad17 PF03215.15 EGG09836.1 - 0.00013 21.9 0.0 0.00047 20.1 0.0 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 EGG09836.1 - 0.00014 21.7 0.0 0.00045 20.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EGG09836.1 - 0.00019 21.3 0.0 0.00049 20.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGG09836.1 - 0.00033 20.1 0.0 0.0074 15.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGG09836.1 - 0.00037 20.5 0.0 0.0011 19.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGG09836.1 - 0.00042 20.4 0.0 0.00081 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGG09836.1 - 0.00054 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG09836.1 - 0.0048 17.4 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF3659 PF12396.8 EGG09836.1 - 0.0049 16.7 0.9 0.0088 15.9 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) AAA_30 PF13604.6 EGG09836.1 - 0.0058 16.4 0.0 0.039 13.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGG09836.1 - 0.0083 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 EGG09836.1 - 0.0086 16.1 0.0 0.22 11.5 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGG09836.1 - 0.0097 16.3 0.0 0.072 13.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGG09836.1 - 0.022 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.29 EGG09836.1 - 0.044 13.5 0.1 0.33 10.7 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_28 PF13521.6 EGG09836.1 - 0.049 13.9 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGG09836.1 - 0.05 13.5 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EGG09836.1 - 0.061 12.5 0.0 0.3 10.3 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EGG09836.1 - 0.14 12.6 0.0 0.4 11.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Pyridoxal_deC PF00282.19 EGG09837.1 - 7.9e-94 314.4 0.0 3.4e-61 207.0 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 EGG09837.1 - 0.042 13.0 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II RPE65 PF03055.15 EGG09838.1 - 9e-105 351.5 0.0 1.1e-104 351.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein CDC45 PF02724.14 EGG09839.1 - 6e-222 738.4 0.0 6.8e-222 738.3 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF1570 PF07607.11 EGG09840.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) USP7_ICP0_bdg PF12436.8 EGG09841.1 - 1.3e-87 293.1 0.1 3.5e-87 291.7 0.0 1.8 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EGG09841.1 - 8.4e-67 224.9 0.5 1.4e-61 207.8 0.1 4.3 4 0 0 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 EGG09841.1 - 2.6e-49 168.1 0.0 5.1e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG09841.1 - 2.6e-22 79.8 0.0 6.2e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EGG09841.1 - 3.1e-10 40.2 0.3 4.6e-09 36.4 0.0 3.0 3 1 0 3 3 3 1 MATH domain HSDR_N_2 PF13588.6 EGG09841.1 - 0.0052 16.8 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) ABC_tran PF00005.27 EGG09842.1 - 2.3e-44 151.2 0.1 1.6e-23 83.7 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGG09842.1 - 3.2e-21 76.4 1.9 1.8e-07 31.3 0.4 4.3 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG09842.1 - 1.6e-14 53.8 0.3 0.0063 16.0 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGG09842.1 - 6.9e-08 32.1 0.1 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 EGG09842.1 - 4.6e-06 27.2 0.0 0.0052 17.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGG09842.1 - 6.4e-06 26.5 0.0 0.21 11.8 0.0 3.5 4 0 0 4 4 3 2 AAA domain DUF87 PF01935.17 EGG09842.1 - 9e-06 25.9 0.0 0.0043 17.2 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 EGG09842.1 - 1.2e-05 25.8 0.0 0.019 15.3 0.0 3.1 3 0 0 3 3 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EGG09842.1 - 2.8e-05 24.2 0.0 0.34 11.0 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG09842.1 - 4.2e-05 23.5 0.0 0.063 13.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 EGG09842.1 - 0.00011 21.3 1.7 0.44 9.5 0.0 3.3 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB 4HB PF17947.1 EGG09842.1 - 0.00012 22.1 0.0 0.00044 20.2 0.0 2.0 1 0 0 1 1 1 1 Four helical bundle domain HEAT_EZ PF13513.6 EGG09842.1 - 0.00022 21.6 8.5 0.65 10.6 0.1 5.7 5 1 1 6 6 5 1 HEAT-like repeat AAA PF00004.29 EGG09842.1 - 0.00022 21.6 0.0 5 7.6 0.0 4.8 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EGG09842.1 - 0.00022 21.0 0.0 0.28 10.9 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 EGG09842.1 - 0.00024 21.3 0.0 1.1 9.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EGG09842.1 - 0.00033 20.9 0.0 0.49 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.6 EGG09842.1 - 0.00035 20.9 6.4 0.0076 16.6 0.5 3.7 3 1 0 3 3 2 1 HEAT repeats NACHT PF05729.12 EGG09842.1 - 0.00059 19.8 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain SbcCD_C PF13558.6 EGG09842.1 - 0.00064 19.9 0.0 0.16 12.3 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EGG09842.1 - 0.0012 19.3 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 EGG09842.1 - 0.0012 18.6 1.6 5.2 6.7 0.0 4.0 4 0 0 4 4 4 0 AAA domain Chromo PF00385.24 EGG09842.1 - 0.0015 18.4 0.1 0.0038 17.1 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 EGG09842.1 - 0.0021 18.6 15.1 0.0062 17.1 0.0 3.4 2 1 0 2 2 1 1 AAA domain HEAT PF02985.22 EGG09842.1 - 0.0036 17.4 10.4 0.25 11.7 0.1 6.0 7 0 0 7 7 4 1 HEAT repeat CLASP_N PF12348.8 EGG09842.1 - 0.0047 16.5 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 CLASP N terminal TsaE PF02367.17 EGG09842.1 - 0.0076 16.3 0.1 2.3 8.3 0.1 2.9 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 EGG09842.1 - 0.016 13.9 1.4 2.3 6.7 0.0 2.9 4 0 0 4 4 3 0 AAA domain AAA_27 PF13514.6 EGG09842.1 - 0.018 14.7 0.1 9 5.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EGG09842.1 - 0.018 14.2 0.2 0.94 8.6 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Cnd1 PF12717.7 EGG09842.1 - 0.022 14.8 0.4 6.4 6.8 0.1 2.8 1 1 2 3 3 3 0 non-SMC mitotic condensation complex subunit 1 NTPase_1 PF03266.15 EGG09842.1 - 0.024 14.6 0.0 4.8 7.0 0.1 3.0 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 EGG09842.1 - 0.04 13.6 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGG09842.1 - 0.042 13.0 0.3 7.7 5.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 EGG09842.1 - 0.05 13.5 0.0 17 5.2 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EGG09842.1 - 0.055 13.0 0.2 5.2 6.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region G-alpha PF00503.20 EGG09842.1 - 0.057 12.6 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 EGG09842.1 - 0.074 12.8 0.0 11 5.7 0.0 3.0 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation CLP1_P PF16575.5 EGG09842.1 - 0.11 12.2 0.0 25 4.6 0.0 3.1 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop cobW PF02492.19 EGG09842.1 - 0.12 12.0 0.4 21 4.7 0.1 3.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 EGG09842.1 - 0.14 11.5 0.1 18 4.6 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 EGG09842.1 - 0.14 12.4 0.1 24 5.1 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGG09842.1 - 0.14 11.9 0.1 9.6 5.9 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dopey_N PF04118.14 EGG09842.1 - 0.17 10.9 0.1 0.43 9.6 0.1 1.6 1 0 0 1 1 1 0 Dopey, N-terminal DUF3584 PF12128.8 EGG09842.1 - 0.22 9.0 4.8 3.5 5.0 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) GNAT_like PF18407.1 EGG09842.1 - 0.23 11.9 3.6 0.42 11.0 1.5 2.7 2 0 0 2 2 1 0 GCN5-related N-acetyltransferase like domain Dynamin_N PF00350.23 EGG09842.1 - 0.48 10.5 2.6 2.9 7.9 0.3 2.9 3 1 0 3 3 2 0 Dynamin family RNA_pol_I_TF PF04090.12 EGG09843.1 - 1.2e-16 60.8 1.6 5.5e-13 48.9 0.2 2.2 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor TPR_14 PF13428.6 EGG09843.1 - 0.08 13.8 0.6 4.7 8.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SPT6_acidic PF14632.6 EGG09845.1 - 0.02 15.5 0.8 2.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Retrotran_gag_2 PF14223.6 EGG09846.1 - 7e-07 29.0 1.7 2.3e-06 27.3 0.0 2.3 2 1 1 3 3 3 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGG09846.1 - 0.097 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RIBIOP_C PF04950.12 EGG09847.1 - 6.9e-114 380.2 0.0 1e-113 379.6 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal CDC45 PF02724.14 EGG09847.1 - 9.6 4.4 7.2 16 3.6 7.2 1.3 1 0 0 1 1 1 0 CDC45-like protein 2-oxoacid_dh PF00198.23 EGG09848.1 - 5.2e-62 209.3 0.0 6e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) AMP-binding PF00501.28 EGG09849.1 - 3.8e-07 29.1 0.0 6e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF3244 PF11589.8 EGG09849.1 - 0.14 12.2 0.0 0.6 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) NICE-1 PF15845.5 EGG09850.1 - 0.47 11.2 5.6 3.5 8.5 0.3 2.4 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family zf-H2C2_2 PF13465.6 EGG09851.1 - 2.1e-26 91.1 27.7 1.5e-06 28.4 0.4 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 EGG09851.1 - 1.8e-16 59.5 28.4 0.00016 21.9 2.3 4.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG09851.1 - 1.9e-13 50.0 26.7 0.00073 20.2 1.4 4.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGG09851.1 - 2.3e-08 34.1 10.2 0.0022 18.2 0.0 4.5 3 1 1 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EGG09851.1 - 1.2e-07 31.5 21.5 0.0027 17.6 1.8 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EGG09851.1 - 0.00055 20.2 10.4 0.0046 17.2 3.0 2.9 1 1 2 3 3 3 2 C2H2-type zinc ribbon Vps39_2 PF10367.9 EGG09851.1 - 0.0032 17.9 1.6 1.1 9.8 0.4 2.5 2 0 0 2 2 2 2 Vacuolar sorting protein 39 domain 2 zf-C2H2_2 PF12756.7 EGG09851.1 - 0.005 17.1 13.5 0.061 13.7 6.6 2.4 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 EGG09851.1 - 0.0071 16.2 6.9 1 9.3 0.3 3.6 4 0 0 4 4 4 2 zinc-finger of a C2HC-type C1_4 PF07975.12 EGG09851.1 - 0.013 15.8 7.6 0.34 11.2 1.4 2.6 2 1 1 3 3 3 0 TFIIH C1-like domain zf-C2H2_3rep PF18868.1 EGG09851.1 - 0.013 16.2 5.0 0.11 13.2 0.6 2.7 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Scramblase PF03803.15 EGG09851.1 - 0.032 13.5 0.2 0.063 12.6 0.0 1.4 1 1 1 2 2 2 0 Scramblase DUF3991 PF13154.6 EGG09851.1 - 0.034 14.5 0.1 9.9 6.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3991) zf-C2H2_9 PF16293.5 EGG09851.1 - 0.039 13.8 1.1 15 5.5 0.0 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 EGG09851.1 - 0.053 13.9 0.3 0.053 13.9 0.3 4.9 5 1 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 EGG09851.1 - 0.17 12.0 5.1 0.33 11.1 3.9 2.1 1 1 0 2 2 2 0 Aberrant zinc-finger Yippee-Mis18 PF03226.14 EGG09851.1 - 0.2 11.9 4.4 8.5 6.6 0.1 2.4 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf_ZIC PF18366.1 EGG09851.1 - 0.54 10.4 6.8 2.7 8.2 0.2 2.9 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-AN1 PF01428.16 EGG09851.1 - 6.2 7.1 11.1 8.9 6.6 0.1 3.8 4 0 0 4 4 4 0 AN1-like Zinc finger adh_short_C2 PF13561.6 EGG09852.1 - 3.4e-57 193.7 0.6 4.4e-57 193.3 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG09852.1 - 2e-47 161.2 1.0 2.4e-47 160.9 1.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG09852.1 - 4e-15 56.2 0.2 5.3e-15 55.8 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG09852.1 - 0.0039 16.7 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EGG09852.1 - 0.031 14.8 0.2 5.2 7.7 0.1 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 EGG09852.1 - 0.041 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGG09852.1 - 0.1 11.7 0.2 0.19 10.9 0.2 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein YAcAr PF10686.9 EGG09852.1 - 0.31 11.0 1.8 0.64 10.0 0.2 2.3 2 1 0 2 2 2 0 YspA, cpYpsA-related SLOG family RloB PF13707.6 EGG09853.1 - 0.014 15.6 0.3 0.019 15.2 0.3 1.2 1 0 0 1 1 1 0 RloB-like protein Pkinase PF00069.25 EGG09854.1 - 8.9e-43 146.5 0.0 1.2e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG09854.1 - 2.7e-19 69.5 0.0 3.4e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG09854.1 - 0.0076 15.6 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGG09854.1 - 0.03 13.7 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGG09854.1 - 0.25 10.1 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase tRNA-synt_1 PF00133.22 EGG09855.1 - 2.5e-141 471.9 0.1 3.4e-141 471.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGG09855.1 - 5.9e-23 81.3 0.1 1.5e-11 43.7 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGG09855.1 - 4e-19 69.1 1.2 9.9e-19 67.8 1.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGG09855.1 - 2.5e-07 30.3 0.0 0.0046 16.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 EGG09855.1 - 0.00024 20.7 0.0 0.00074 19.1 0.0 1.7 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 EGG09855.1 - 0.072 12.0 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) zf-FPG_IleRS PF06827.14 EGG09855.1 - 0.11 12.3 2.0 0.26 11.2 2.0 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS DUF3195 PF11424.8 EGG09856.1 - 0.078 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) NUC194 PF08163.12 EGG09856.1 - 0.1 11.5 0.4 0.12 11.3 0.4 1.0 1 0 0 1 1 1 0 NUC194 domain DUF2170 PF09938.9 EGG09856.1 - 0.16 11.7 0.0 0.19 11.4 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) PQ-loop PF04193.14 EGG09859.1 - 0.017 14.9 0.1 0.4 10.5 0.0 2.7 3 0 0 3 3 3 0 PQ loop repeat Per1 PF04080.13 EGG09860.1 - 3e-20 73.1 1.6 5.8e-12 45.9 0.3 2.1 2 0 0 2 2 2 2 Per1-like family DNA_pol_phi PF04931.13 EGG09862.1 - 3.9 5.5 21.5 6.3 4.8 21.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi AAA_18 PF13238.6 EGG09863.1 - 1.5e-27 96.7 0.1 3.4e-27 95.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 EGG09863.1 - 0.00027 20.9 0.8 0.0042 17.0 0.1 2.0 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA PF00004.29 EGG09863.1 - 0.00055 20.4 0.0 0.0025 18.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 EGG09863.1 - 0.0006 19.2 0.2 0.0036 16.7 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.6 EGG09863.1 - 0.0014 19.1 0.0 0.0037 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGG09863.1 - 0.0018 18.5 0.1 0.006 16.8 0.0 1.9 2 1 1 3 3 2 1 AAA domain AAA_22 PF13401.6 EGG09863.1 - 0.004 17.4 0.0 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EGG09863.1 - 0.0071 16.3 0.3 0.025 14.5 0.1 1.9 2 0 0 2 2 2 1 NTPase Thymidylate_kin PF02223.17 EGG09863.1 - 0.0082 15.8 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_16 PF13191.6 EGG09863.1 - 0.011 16.2 0.0 0.012 16.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 EGG09863.1 - 0.018 14.4 0.1 0.089 12.1 0.0 1.9 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 EGG09863.1 - 0.047 12.7 0.1 0.076 12.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 EGG09863.1 - 0.052 13.9 0.5 0.11 12.9 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGG09863.1 - 0.056 13.6 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pyr_excise PF03013.14 EGG09863.1 - 0.061 13.3 0.1 0.097 12.6 0.1 1.4 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase DUF768 PF05589.11 EGG09863.1 - 0.061 13.3 0.4 0.14 12.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Sigma54_activat PF00158.26 EGG09863.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.9 EGG09863.1 - 0.08 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 EGG09863.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGG09863.1 - 0.14 12.0 0.1 0.36 10.6 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EGG09863.1 - 0.32 10.7 0.7 1.6 8.4 0.5 1.9 1 1 1 2 2 2 0 AAA domain DUF2052 PF09747.9 EGG09868.1 - 0.63 10.1 11.6 0.92 9.6 11.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AAA_11 PF13086.6 EGG09868.1 - 6.3 6.5 10.1 9 6.0 10.1 1.2 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 EGG09868.1 - 9.8 5.9 16.2 14 5.4 16.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PALP PF00291.25 EGG09869.1 - 3e-73 246.8 0.1 3.9e-73 246.4 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EGG09869.1 - 1.3e-35 121.1 0.1 8.5e-20 70.3 0.0 3.5 2 1 1 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase DPBB_1 PF03330.18 EGG09870.1 - 0.00044 20.5 0.0 0.00075 19.7 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase NmrA PF05368.13 EGG09871.1 - 1.5e-23 83.5 0.2 2.2e-23 83.0 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGG09871.1 - 3e-10 40.3 0.0 4.7e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGG09871.1 - 4.8e-05 22.5 0.0 8.1e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EGG09871.1 - 0.00041 20.6 0.1 0.0008 19.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EGG09871.1 - 0.0087 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EGG09871.1 - 0.039 14.1 0.1 0.099 12.8 0.1 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 EGG09872.1 - 5.5e-24 85.0 0.2 8e-24 84.5 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGG09872.1 - 4.3e-09 36.5 0.0 7.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGG09872.1 - 0.00013 21.1 0.4 0.0011 18.1 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EGG09872.1 - 0.0084 16.2 0.2 0.056 13.6 0.2 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 EGG09872.1 - 0.08 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 EGG09872.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF2465 PF10239.9 EGG09874.1 - 0.078 12.2 0.2 0.096 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) TINF2_N PF14973.6 EGG09874.1 - 0.12 12.7 0.3 0.27 11.6 0.3 1.6 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus EssA PF10661.9 EGG09875.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA SAP PF02037.27 EGG09876.1 - 7.5e-05 22.4 0.7 0.00017 21.2 0.3 1.9 2 0 0 2 2 2 1 SAP domain LEM PF03020.15 EGG09876.1 - 0.02 14.4 0.1 0.057 13.0 0.0 1.8 2 0 0 2 2 2 0 LEM domain Rho_N PF07498.12 EGG09876.1 - 0.031 14.2 0.2 0.053 13.5 0.2 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Ish1 PF10281.9 EGG09876.1 - 0.047 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Dicistro_VP4 PF11492.8 EGG09876.1 - 0.061 13.3 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 Pyr_redox_dim PF02852.22 EGG09877.1 - 0.18 12.1 0.0 0.4 11.0 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain NPR1_interact PF15699.5 EGG09879.1 - 0.051 14.2 0.3 0.075 13.7 0.3 1.3 1 0 0 1 1 1 0 NPR1 interacting NCU-G1 PF15065.6 EGG09879.1 - 0.052 12.5 0.3 0.052 12.5 0.3 1.6 2 0 0 2 2 2 0 Lysosomal transcription factor, NCU-G1 Gemini_mov PF01708.16 EGG09879.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Geminivirus putative movement protein Ribosomal_S30 PF04758.14 EGG09880.1 - 2e-25 88.8 6.8 2.4e-25 88.5 6.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DUF1057 PF06342.12 EGG09884.1 - 0.0076 15.3 0.1 0.037 13.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) TMEM154 PF15102.6 EGG09886.1 - 0.0024 17.8 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Pkinase PF00069.25 EGG09887.1 - 1.1e-45 156.1 0.1 2.3e-45 155.0 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG09887.1 - 9.3e-24 84.1 0.0 1.3e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EGG09887.1 - 0.00071 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EGG09887.1 - 0.0028 17.3 0.6 0.028 14.0 0.6 2.2 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EGG09887.1 - 0.013 14.3 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGG09887.1 - 0.078 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP19 PF11022.8 EGG09895.1 - 0.26 11.7 0.7 0.47 10.9 0.1 1.7 2 0 0 2 2 2 0 ATP synthase subunit K FXMRP1_C_core PF12235.8 EGG09896.1 - 0.098 13.3 26.3 0.39 11.4 12.7 2.6 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Glyco_hydro_10 PF00331.20 EGG09898.1 - 1.7e-88 296.8 0.0 2e-88 296.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 GCM PF03615.15 EGG09899.1 - 0.029 14.2 0.6 0.064 13.1 0.6 1.5 1 0 0 1 1 1 0 GCM motif protein SPATIAL PF15256.6 EGG09900.1 - 0.1 12.9 2.6 0.14 12.5 2.6 1.2 1 0 0 1 1 1 0 SPATIAL Ferritin_2 PF13668.6 EGG09902.1 - 5.3e-36 123.8 1.5 6.3e-36 123.6 1.5 1.1 1 0 0 1 1 1 1 Ferritin-like domain CHORD PF04968.12 EGG09903.1 - 1.2e-49 166.8 20.9 4.5e-26 91.4 7.2 2.5 2 0 0 2 2 2 2 CHORD CS PF04969.16 EGG09903.1 - 1.4e-12 48.4 0.4 3.9e-12 47.0 0.4 1.8 1 0 0 1 1 1 1 CS domain BTK PF00779.19 EGG09903.1 - 0.18 11.6 0.3 0.18 11.6 0.3 3.2 4 0 0 4 4 4 0 BTK motif DUF4148 PF13663.6 EGG09904.1 - 0.031 14.5 0.3 0.045 13.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) HhH-GPD PF00730.25 EGG09905.1 - 5.9e-17 62.1 0.0 8.1e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein YrhK PF14145.6 EGG09907.1 - 0.13 12.1 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 YrhK-like protein TetR_C_18 PF17923.1 EGG09907.1 - 0.13 12.8 0.2 0.38 11.3 0.2 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain B56 PF01603.20 EGG09908.1 - 2e-191 636.4 2.2 2.8e-191 636.0 2.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) SUIM_assoc PF16619.5 EGG09908.1 - 0.062 13.4 12.9 1.3 9.2 7.2 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TAFII55_N PF04658.13 EGG09910.1 - 2.8e-52 176.6 1.2 2.8e-52 176.6 1.2 2.0 2 0 0 2 2 2 1 TAFII55 protein conserved region Surfac_D-trimer PF09006.11 EGG09910.1 - 0.039 13.8 0.3 0.087 12.7 0.3 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation BUD22 PF09073.10 EGG09910.1 - 0.093 12.1 11.6 0.13 11.6 11.6 1.2 1 0 0 1 1 1 0 BUD22 SURF2 PF05477.11 EGG09910.1 - 0.12 12.1 6.0 0.21 11.3 6.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Rrp44_CSD1 PF17216.3 EGG09910.1 - 0.2 11.4 5.4 0.24 11.1 4.2 1.8 2 0 0 2 2 2 0 Rrp44-like cold shock domain Nop14 PF04147.12 EGG09910.1 - 1.2 7.2 22.1 1.5 7.0 22.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EGG09910.1 - 1.6 8.1 18.4 2.2 7.6 18.4 1.2 1 0 0 1 1 1 0 SDA1 SGT1 PF07093.11 EGG09910.1 - 1.8 6.9 7.9 2.4 6.5 7.9 1.1 1 0 0 1 1 1 0 SGT1 protein PAC1 PF16094.5 EGG09910.1 - 2.1 7.4 3.9 4.2 6.4 3.9 1.5 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 CDC45 PF02724.14 EGG09910.1 - 4.3 5.5 15.3 5.9 5.1 15.3 1.1 1 0 0 1 1 1 0 CDC45-like protein HMGL-like PF00682.19 EGG09913.1 - 1.5e-76 257.4 0.0 2.4e-76 256.8 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EGG09913.1 - 2e-22 79.5 0.5 3.7e-22 78.6 0.5 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Lipase_GDSL_2 PF13472.6 EGG09914.1 - 3.3e-28 99.3 0.2 4.4e-28 98.9 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGG09914.1 - 6.3e-21 75.3 0.0 8.3e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4267 PF14087.6 EGG09915.1 - 0.023 14.7 5.5 0.06 13.4 5.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) TMEM154 PF15102.6 EGG09916.1 - 0.0029 17.5 0.2 0.0029 17.5 0.2 1.9 2 0 0 2 2 2 1 TMEM154 protein family RIFIN PF02009.16 EGG09916.1 - 0.0048 16.8 0.2 0.0081 16.1 0.2 1.3 1 0 0 1 1 1 1 Rifin EphA2_TM PF14575.6 EGG09916.1 - 0.018 15.9 0.5 0.047 14.6 0.5 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Vpu PF00558.19 EGG09916.1 - 0.079 12.7 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 Vpu protein LMBR1 PF04791.16 EGG09916.1 - 0.091 11.6 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MAP17 PF15807.5 EGG09916.1 - 0.2 11.9 0.3 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Syndecan PF01034.20 EGG09916.1 - 0.22 11.4 3.0 0.46 10.4 3.0 1.5 1 0 0 1 1 1 0 Syndecan domain ECSCR PF15820.5 EGG09916.1 - 0.73 9.7 2.6 0.48 10.3 0.1 1.9 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Insulin_TMD PF17870.1 EGG09916.1 - 4.4 7.5 5.7 1.5 9.0 1.8 2.1 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment CxC5 PF18718.1 EGG09917.1 - 6.9e-33 113.2 5.7 8.9e-33 112.8 5.7 1.1 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 EGG09917.1 - 0.046 13.6 0.6 0.1 12.5 0.1 1.6 1 1 1 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases PAP_assoc PF03828.19 EGG09918.1 - 1.2e-17 63.8 0.1 1.2e-17 63.8 0.1 2.9 3 0 0 3 3 3 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGG09918.1 - 3.2e-10 40.1 2.2 5.8e-10 39.3 0.0 2.6 2 1 0 2 2 2 1 Nucleotidyltransferase domain DUF1515 PF07439.11 EGG09918.1 - 0.15 12.1 0.1 0.37 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Glyco_hydro_88 PF07470.13 EGG09920.1 - 4.6e-14 52.3 2.9 7.2e-14 51.6 2.9 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DEAD PF00270.29 EGG09921.1 - 2.6e-29 102.2 0.0 4.8e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG09921.1 - 3e-26 91.9 0.0 1.1e-24 86.9 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG09921.1 - 1.1e-05 25.5 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGG09921.1 - 0.082 13.2 0.1 15 5.9 0.0 2.8 2 1 1 3 3 3 0 AAA domain DsrH PF04077.12 EGG09921.1 - 0.091 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 DsrH like protein Wbp11 PF09429.10 EGG09921.1 - 0.24 11.8 4.1 2 8.9 0.2 2.7 2 0 0 2 2 2 0 WW domain binding protein 11 Hydantoinase_A PF01968.18 EGG09922.1 - 5.4e-96 321.3 0.2 2.8e-95 318.9 0.0 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGG09922.1 - 2.2e-59 200.1 0.4 1.2e-56 191.2 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Methyltransf_2 PF00891.18 EGG09924.1 - 4.2e-11 42.5 0.0 9.2e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGG09924.1 - 0.01 15.8 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Dimerisation PF08100.11 EGG09924.1 - 0.022 14.8 0.1 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 Dimerisation domain Asp PF00026.23 EGG09925.1 - 6.3e-51 173.7 0.7 2.1e-50 172.0 0.7 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG09925.1 - 2.5e-11 44.1 0.9 0.00055 20.2 0.1 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGG09925.1 - 0.002 17.9 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal PDCD2_C PF04194.13 EGG09926.1 - 1.9e-32 112.7 0.1 1.9e-32 112.7 0.1 2.0 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Helicase_C PF00271.31 EGG09927.1 - 0.019 15.3 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Helicase_C_3 PF13625.6 EGG09927.1 - 0.15 12.2 0.0 6.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Helicase conserved C-terminal domain SAGA-Tad1 PF12767.7 EGG09929.1 - 6.3e-54 183.2 5.1 6.3e-54 183.2 5.1 2.8 2 1 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit tRNA_int_endo PF01974.17 EGG09932.1 - 4.7e-10 39.4 0.0 9.7e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Tyr_Deacylase PF02580.16 EGG09933.1 - 1e-49 168.7 0.0 1.3e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase GLTP PF08718.11 EGG09934.1 - 5.9e-49 166.2 0.0 8e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) CAP18_C PF12153.8 EGG09934.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) L31 PF09784.9 EGG09935.1 - 3.3e-37 127.0 0.2 3.6e-37 126.9 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Glyco_hydro_18 PF00704.28 EGG09936.1 - 2.4e-53 181.9 0.2 3.3e-53 181.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 EGG09936.1 - 0.0046 16.4 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 BET PF17035.5 EGG09937.1 - 0.37 11.0 1.4 26 5.1 0.2 2.6 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation Aminotran_1_2 PF00155.21 EGG09938.1 - 0.0003 20.1 0.0 0.00091 18.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGG09938.1 - 0.0042 15.9 0.0 0.49 9.1 0.0 2.2 2 0 0 2 2 2 2 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.21 EGG09939.1 - 2.4e-22 79.6 0.0 3e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGG09939.1 - 3.4e-12 45.9 0.0 4.5e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DUF3483 PF11982.8 EGG09940.1 - 0.18 11.4 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) HMG_box PF00505.19 EGG09941.1 - 0.016 15.6 0.2 0.21 12.0 0.1 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box CAMSAP_CH PF11971.8 EGG09942.1 - 0.1 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 CAMSAP CH domain OTU PF02338.19 EGG09943.1 - 5.4e-05 23.7 0.0 9.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.8 EGG09943.1 - 0.00015 22.2 0.1 0.0004 20.8 0.0 1.8 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 UBX PF00789.20 EGG09943.1 - 0.00031 20.9 0.0 0.00058 20.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain zf-C2H2_2 PF12756.7 EGG09943.1 - 0.0084 16.4 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Ras PF00071.22 EGG09944.1 - 1.9e-53 180.4 0.0 2.1e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG09944.1 - 4.5e-19 68.8 0.0 6e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG09944.1 - 1.2e-06 28.1 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG09944.1 - 0.077 12.5 0.0 0.55 9.7 0.0 2.2 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Rnk_N PF14760.6 EGG09944.1 - 0.15 12.6 1.0 0.91 10.1 0.1 2.1 2 0 0 2 2 2 0 Rnk N-terminus PRT_C PF08372.10 EGG09946.1 - 0.096 12.4 0.2 0.28 10.9 0.1 1.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal PUF PF00806.19 EGG09949.1 - 2.1e-21 74.3 0.2 7.8e-05 22.2 0.1 5.6 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EGG09949.1 - 1.6e-15 56.7 0.0 1.2e-08 34.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EGG09950.1 - 1.5e-08 35.1 10.6 0.00085 20.1 0.2 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG09950.1 - 0.00066 19.9 0.2 0.61 10.4 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PMC2NT PF08066.12 EGG09951.1 - 0.00016 22.3 0.3 0.00027 21.6 0.3 1.5 1 0 0 1 1 1 1 PMC2NT (NUC016) domain DUF3117 PF11314.8 EGG09953.1 - 0.035 13.9 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3117) MCM PF00493.23 EGG09955.1 - 4.7e-103 343.1 0.0 1e-102 342.0 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGG09955.1 - 3.3e-32 111.0 0.6 5.7e-32 110.2 0.6 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGG09955.1 - 1.8e-20 73.1 0.8 5.2e-20 71.7 0.8 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGG09955.1 - 2.7e-12 47.2 1.2 7.3e-12 45.8 1.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGG09955.1 - 1.7e-07 30.9 0.0 1.4e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGG09955.1 - 4.2e-07 30.0 0.0 1.5e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EGG09955.1 - 0.014 15.2 0.2 0.04 13.8 0.2 1.7 1 0 0 1 1 1 0 AAA lid domain AAA_3 PF07726.11 EGG09955.1 - 0.014 15.2 0.0 0.044 13.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EGG09955.1 - 0.035 14.7 0.4 0.14 12.8 0.2 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Sigma54_activat PF00158.26 EGG09955.1 - 0.08 12.6 0.0 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-C2H2_aberr PF17017.5 EGG09957.1 - 0.085 13.0 0.0 9.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger PCI PF01399.27 EGG09959.1 - 4.6e-05 23.9 0.3 4.6e-05 23.9 0.3 2.3 3 0 0 3 3 3 1 PCI domain Ycf54 PF10674.9 EGG09959.1 - 0.082 13.2 0.1 0.25 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) Sas6_CC PF18594.1 EGG09960.1 - 0.2 11.5 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain NOA36 PF06524.12 EGG09960.1 - 7.8 5.7 7.7 11 5.2 7.7 1.2 1 0 0 1 1 1 0 NOA36 protein Cu_bind_like PF02298.17 EGG09962.1 - 0.00037 20.5 0.0 0.0089 16.0 0.0 2.3 1 1 0 1 1 1 1 Plastocyanin-like domain Cupredoxin_1 PF13473.6 EGG09962.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 Cupredoxin-like domain HALZ PF02183.18 EGG09963.1 - 0.0037 17.5 0.0 0.0058 16.8 0.0 1.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper Baculo_PEP_C PF04513.12 EGG09965.1 - 0.0029 17.6 7.2 0.0066 16.5 7.2 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 EGG09965.1 - 0.038 13.3 0.8 0.063 12.6 0.8 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin CENP-Q PF13094.6 EGG09965.1 - 0.042 14.1 0.5 0.075 13.2 0.5 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ribosomal_60s PF00428.19 EGG09965.1 - 0.16 12.6 1.6 0.73 10.5 1.6 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein LRR_4 PF12799.7 EGG09966.1 - 0.0092 16.4 2.8 4.8 7.7 0.1 3.7 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EGG09966.1 - 0.016 15.1 2.4 0.029 14.3 2.1 1.3 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EGG09966.1 - 0.34 10.7 3.2 0.3 10.9 1.2 2.1 2 1 0 2 2 2 0 Leucine rich repeat Vps5 PF09325.10 EGG09968.1 - 0.046 13.3 2.5 0.071 12.6 2.5 1.2 1 0 0 1 1 1 0 Vps5 C terminal like DUF1664 PF07889.12 EGG09968.1 - 0.061 13.4 2.0 0.14 12.2 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EGG09968.1 - 0.079 13.4 12.2 0.058 13.9 5.0 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein MbeD_MobD PF04899.12 EGG09968.1 - 0.099 12.8 1.0 8 6.7 0.2 2.7 1 1 1 2 2 2 0 MbeD/MobD like Laminin_II PF06009.12 EGG09968.1 - 0.16 12.0 4.7 2.6 8.1 3.9 2.2 2 0 0 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 EGG09968.1 - 0.34 11.3 3.7 2.8 8.3 2.4 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phasin PF05597.11 EGG09968.1 - 0.37 10.8 4.4 8.4 6.4 1.3 2.9 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) LPP PF04728.13 EGG09968.1 - 0.69 10.3 10.4 0.52 10.7 1.4 3.2 1 1 2 3 3 3 0 Lipoprotein leucine-zipper DUF948 PF06103.11 EGG09968.1 - 0.71 10.2 5.7 4.6 7.6 1.9 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Ank_2 PF12796.7 EGG09969.1 - 1.2e-06 29.1 0.0 3.2e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG09969.1 - 2.2e-06 28.1 0.0 4.9e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGG09969.1 - 1.2e-05 25.5 0.0 3.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 EGG09969.1 - 1.7e-05 25.0 0.0 3.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG09969.1 - 8.1e-05 22.7 0.0 0.00025 21.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Glyco_transf_21 PF13506.6 EGG09971.1 - 7.9e-24 84.1 0.0 6.4e-20 71.3 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EGG09971.1 - 1.9e-13 50.8 0.0 2.5e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGG09971.1 - 0.00049 20.1 0.4 0.00049 20.1 0.4 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGG09971.1 - 0.0013 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 RRM_1 PF00076.22 EGG09973.1 - 6.7e-36 121.9 0.0 3.6e-19 68.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG09973.1 - 0.0014 18.7 0.0 0.0042 17.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 EGG09973.1 - 0.014 15.1 0.2 0.53 10.0 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 EGG09973.1 - 0.13 12.4 0.0 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 Aldedh PF00171.22 EGG09976.1 - 1.8e-180 600.4 0.0 2e-180 600.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF5063 PF16702.5 EGG09976.1 - 0.058 13.8 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5063) NAP PF00956.18 EGG09979.1 - 0.032 13.4 1.8 0.058 12.6 1.8 1.4 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) V_ATPase_I PF01496.19 EGG09981.1 - 0 1034.1 0.0 0 1033.9 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family PI3K_P85_iSH2 PF16454.5 EGG09981.1 - 0.15 11.7 0.2 0.3 10.7 0.2 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ATG16 PF08614.11 EGG09981.1 - 0.38 11.0 2.4 0.81 9.9 0.5 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Torus PF16131.5 EGG09982.1 - 3.5e-08 34.1 0.1 8.5e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 EGG09982.1 - 0.00015 21.7 3.9 0.00043 20.2 3.9 1.9 1 0 0 1 1 1 1 Zinc finger domain RRM_1 PF00076.22 EGG09982.1 - 0.0015 18.3 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 EGG09982.1 - 0.0037 17.5 0.1 0.015 15.5 0.1 2.0 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGG09982.1 - 0.0086 16.5 1.4 0.031 14.8 1.4 2.0 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EGG09982.1 - 0.015 15.1 3.6 0.038 13.8 3.6 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger FYVE PF01363.21 EGG09982.1 - 0.017 15.3 0.2 0.017 15.3 0.2 1.9 2 0 0 2 2 2 0 FYVE zinc finger zf-CCCH PF00642.24 EGG09982.1 - 0.027 14.4 2.7 0.027 14.4 2.7 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_occluded PF16842.5 EGG09982.1 - 0.033 14.1 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif GRIP PF01465.20 EGG09983.1 - 2e-05 24.4 0.2 6.6e-05 22.7 0.2 1.9 1 0 0 1 1 1 1 GRIP domain Filament PF00038.21 EGG09983.1 - 0.068 12.7 70.1 0.053 13.1 18.1 4.0 1 1 3 4 4 4 0 Intermediate filament protein Fez1 PF06818.15 EGG09983.1 - 0.15 12.5 66.2 1.7 9.0 20.2 3.7 1 1 1 3 3 3 0 Fez1 TPR_MLP1_2 PF07926.12 EGG09983.1 - 0.61 10.1 78.8 0.35 11.0 12.7 5.0 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EGG09983.1 - 3.9 7.5 78.5 1.1 9.2 15.6 5.2 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 EGG09983.1 - 6.4 4.2 69.4 7.8 3.9 36.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 EGG09983.1 - 6.9 7.2 80.5 15 6.1 14.7 5.2 1 1 4 5 5 5 0 Apg6 coiled-coil region WD40 PF00400.32 EGG09984.1 - 3.9e-32 109.8 24.2 2.5e-08 34.4 1.0 7.2 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG09984.1 - 1.5e-10 41.3 2.3 0.015 15.6 0.0 5.3 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG09984.1 - 0.00023 21.1 0.1 0.34 10.8 0.0 3.4 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EGG09984.1 - 0.00032 20.5 0.0 8.8 6.4 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DUF4221 PF13970.6 EGG09984.1 - 0.083 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) DUF4605 PF15378.6 EGG09984.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) HMG_box PF00505.19 EGG09985.1 - 0.00078 19.8 0.1 0.00078 19.8 0.1 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGG09985.1 - 0.0039 17.7 1.2 0.0064 17.1 0.1 1.9 2 0 0 2 2 2 1 HMG-box domain Carot_N PF09150.10 EGG09985.1 - 0.093 12.6 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Orange carotenoid protein, N-terminal Cytadhesin_P30 PF07271.11 EGG09985.1 - 0.72 9.4 10.0 1.3 8.5 10.0 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 zf-CCHC_2 PF13696.6 EGG09987.1 - 0.012 15.4 0.9 0.02 14.7 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGG09987.1 - 0.021 14.6 0.3 0.038 13.7 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EGG09987.1 - 0.07 13.2 0.8 0.12 12.4 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle HTH_ABP1_N PF18107.1 EGG09988.1 - 2.1e-08 33.8 0.0 2.7e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain CENP-B_N PF04218.13 EGG09988.1 - 0.064 12.9 0.6 0.19 11.4 0.6 2.0 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF3746 PF12562.8 EGG09988.1 - 2.1 8.3 4.6 9.3 6.3 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3746) TipE PF16972.5 EGG09996.1 - 0.031 13.5 0.1 0.058 12.6 0.1 1.3 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE NAD_binding_4 PF07993.12 EGG09997.1 - 0.002 17.4 0.2 0.0044 16.2 0.0 1.5 1 1 1 2 2 2 1 Male sterility protein DUF4965 PF16335.5 EGG09999.1 - 2.5e-17 63.1 0.5 7.1e-17 61.6 0.0 2.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EGG09999.1 - 1.1e-06 28.7 0.5 0.007 16.2 0.2 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF5127) DUF1793 PF08760.11 EGG10000.1 - 6.4e-13 49.5 0.1 7.8e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4648 PF15505.6 EGG10001.1 - 0.1 13.5 0.3 0.23 12.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) DUF43 PF01861.16 EGG10001.1 - 0.15 11.3 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain GATase_6 PF13522.6 EGG10006.1 - 1.7e-13 51.0 0.0 3.8e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGG10006.1 - 6.2e-10 39.0 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EGG10006.1 - 9.1e-08 31.8 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EGG10006.1 - 3.4e-06 26.2 0.0 1e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II AP_endonuc_2 PF01261.24 EGG10006.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel PSY3 PF16836.5 EGG10006.1 - 0.19 11.2 0.0 0.6 9.6 0.0 1.8 2 0 0 2 2 2 0 Shu complex component Psy3, DNA-binding description SURF1 PF02104.15 EGG10007.1 - 6.8e-45 153.5 0.0 1.1e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 SURF1 family DUF3852 PF12963.7 EGG10008.1 - 0.032 14.6 0.3 0.057 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) ADK PF00406.22 EGG10009.1 - 2e-58 196.8 0.0 2.8e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGG10009.1 - 1.7e-23 83.6 0.2 4.2e-23 82.3 0.1 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EGG10009.1 - 1.1e-17 63.7 0.0 2e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EGG10009.1 - 0.0076 16.8 0.0 0.019 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGG10009.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bap31_Bap29_C PF18035.1 EGG10009.1 - 0.51 10.4 4.5 20 5.3 0.1 3.3 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Paf67 PF10255.9 EGG10010.1 - 7.8e-159 529.0 0.0 1e-158 528.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EGG10010.1 - 0.13 12.4 0.7 0.61 10.3 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_38 PF13936.6 EGG10014.1 - 0.14 11.9 0.0 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Shugoshin_C PF07557.11 EGG10016.1 - 2.7e-10 39.9 6.4 2.7e-10 39.9 6.4 2.4 2 0 0 2 2 2 1 Shugoshin C terminus Shugoshin_N PF07558.11 EGG10016.1 - 1.4e-06 28.1 6.7 5.2e-06 26.2 6.7 2.1 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DEAD PF00270.29 EGG10017.1 - 2.7e-34 118.5 0.0 4.7e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG10017.1 - 2.6e-26 92.1 0.0 9.1e-26 90.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG10017.1 - 1.1e-05 25.5 0.0 7.5e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YadA_stalk PF05662.14 EGG10018.1 - 1.6 9.1 4.3 0.95 9.9 0.9 2.1 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin G6PD_C PF02781.16 EGG10020.1 - 8e-112 373.2 0.0 1.4e-111 372.4 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EGG10020.1 - 6.7e-58 196.2 0.0 2e-57 194.7 0.0 1.8 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GRDP-like PF07173.12 EGG10022.1 - 2.7e-18 67.0 0.7 1.6e-14 54.8 0.0 2.8 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like RRM_1 PF00076.22 EGG10024.1 - 7.1e-08 32.2 0.0 2e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGG10024.1 - 0.017 15.1 0.3 0.068 13.2 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif DUF3231 PF11553.8 EGG10024.1 - 0.02 14.6 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) RRM_occluded PF16842.5 EGG10024.1 - 0.025 14.4 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif CM_2 PF01817.21 EGG10025.1 - 0.0039 17.5 0.5 0.031 14.6 0.1 2.5 2 1 0 2 2 2 1 Chorismate mutase type II RNB PF00773.19 EGG10026.1 - 2.6e-101 339.2 0.0 4.1e-101 338.6 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EGG10026.1 - 4.6e-24 84.2 0.0 1.1e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EGG10026.1 - 3.9e-22 78.4 0.1 3.9e-22 78.4 0.1 2.0 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 EGG10026.1 - 0.00053 20.1 0.0 0.33 11.1 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 EGG10026.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Rrp44-like cold shock domain Ank_4 PF13637.6 EGG10027.1 - 0.0034 17.9 0.1 26 5.5 0.0 4.3 4 2 2 6 6 6 3 Ankyrin repeats (many copies) PGM_PMM_I PF02878.16 EGG10028.1 - 2.9e-36 124.2 0.1 4.3e-36 123.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EGG10028.1 - 2.8e-26 92.0 0.0 4.7e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGG10028.1 - 5.5e-16 59.1 0.0 1.3e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EGG10028.1 - 2.6e-07 30.7 0.0 5.8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF4965 PF16335.5 EGG10030.1 - 7.7e-73 243.8 0.0 1.3e-72 243.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EGG10030.1 - 1.6e-65 221.1 0.7 2.9e-65 220.3 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 EGG10030.1 - 5.8e-59 199.3 0.0 9.9e-59 198.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EGG10030.1 - 7.8e-05 22.2 0.0 0.44 10.1 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4964) Synaptobrevin PF00957.21 EGG10032.1 - 0.0012 18.6 8.2 0.23 11.3 1.7 2.4 1 1 1 2 2 2 2 Synaptobrevin V_ATPase_I PF01496.19 EGG10032.1 - 0.0029 15.6 5.8 0.003 15.6 5.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family N6_N4_Mtase PF01555.18 EGG10032.1 - 0.038 13.7 6.8 0.05 13.3 6.8 1.3 1 0 0 1 1 1 0 DNA methylase Chordopox_A33R PF05966.12 EGG10032.1 - 0.053 12.8 0.1 0.077 12.3 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein LPP PF04728.13 EGG10032.1 - 0.32 11.4 4.7 8.3 6.9 0.6 2.4 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Suf PF05843.14 EGG10032.1 - 0.55 10.2 10.1 0.7 9.8 10.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Borrelia_P83 PF05262.11 EGG10032.1 - 0.69 8.3 25.1 0.86 8.0 25.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PA26 PF04636.13 EGG10032.1 - 0.7 8.8 11.6 0.87 8.4 11.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) kleA_kleC PF17383.2 EGG10032.1 - 0.72 10.2 14.8 0.91 9.9 1.2 3.2 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A SAPS PF04499.15 EGG10032.1 - 1.6 7.4 15.6 2 7.1 15.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein EMP24_GP25L PF01105.24 EGG10032.1 - 2 8.3 10.2 3.4 7.6 10.2 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Allexi_40kDa PF05549.11 EGG10032.1 - 2.1 7.8 15.6 3 7.3 15.6 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein UPF0242 PF06785.11 EGG10032.1 - 5.8 7.0 25.0 8.7 6.4 25.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SLC12 PF03522.15 EGG10032.1 - 8.3 5.3 17.7 9.9 5.1 17.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Exonuc_VII_L PF02601.15 EGG10032.1 - 8.7 5.8 19.4 11 5.5 19.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cu-oxidase_3 PF07732.15 EGG10034.1 - 2.2e-46 156.7 3.9 1.3e-43 147.7 1.0 3.3 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG10034.1 - 5.8e-36 123.2 1.0 5.6e-30 103.9 0.0 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGG10034.1 - 8.8e-26 90.9 0.1 2.9e-23 82.7 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase DASH_Dam1 PF08653.10 EGG10035.1 - 7.7e-22 76.9 0.2 1.3e-21 76.1 0.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 DFP PF04127.15 EGG10036.1 - 0.022 14.6 0.3 0.022 14.6 0.3 1.9 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein SMYLE_N PF18615.1 EGG10036.1 - 0.12 11.9 8.1 0.023 14.3 3.8 1.7 1 1 1 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain zf-ribbon_3 PF13248.6 EGG10036.1 - 0.19 11.2 0.8 3.8 7.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF3042 PF11240.8 EGG10036.1 - 1.7 8.7 4.6 0.32 11.0 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) BPL_N PF09825.9 EGG10036.1 - 5.7 5.9 8.0 6.5 5.7 8.0 1.2 1 1 0 1 1 1 0 Biotin-protein ligase, N terminal Peroxidase_2 PF01328.17 EGG10037.1 - 4.7e-26 92.5 0.0 8.9e-26 91.6 0.0 1.4 1 1 1 2 2 2 1 Peroxidase, family 2 CTP_transf_like PF01467.26 EGG10038.1 - 1.6e-24 86.7 0.0 2.1e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Chitin_synth_1 PF01644.17 EGG10040.1 - 9.8e-81 269.5 0.1 1.5e-80 268.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGG10040.1 - 2.6e-30 104.2 0.9 7.5e-30 102.7 0.3 2.1 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGG10040.1 - 1.1e-22 80.4 1.7 4.3e-18 65.2 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGG10040.1 - 4.1e-06 26.9 0.9 4.1e-06 26.9 0.9 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 DUF2964 PF11177.8 EGG10040.1 - 0.83 9.9 4.2 0.52 10.5 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) GH131_N PF18271.1 EGG10042.1 - 4.8e-56 190.3 0.0 5.9e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain GH131_N PF18271.1 EGG10043.1 - 2.3e-54 184.8 0.0 2.6e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Aldedh PF00171.22 EGG10044.1 - 1.1e-156 522.0 0.0 1.4e-156 521.7 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FMO-like PF00743.19 EGG10047.1 - 9.3e-12 44.1 0.5 2.1e-10 39.7 0.2 2.8 1 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGG10047.1 - 9.6e-11 41.4 0.0 2.6e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG10047.1 - 3.3e-10 39.7 0.0 1.6e-07 30.9 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG10047.1 - 1.3e-08 35.0 0.4 1.8e-07 31.3 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EGG10047.1 - 1e-05 24.9 0.2 0.00012 21.3 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EGG10047.1 - 1.4e-05 24.9 3.1 4.4e-05 23.2 3.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGG10047.1 - 5.6e-05 23.2 1.1 0.00028 20.9 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EGG10047.1 - 0.00035 21.1 3.8 0.27 11.8 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGG10047.1 - 0.0014 17.9 1.3 0.02 14.2 0.0 2.4 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EGG10047.1 - 0.0019 18.1 0.4 0.0019 18.1 0.4 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EGG10047.1 - 0.0051 16.2 5.6 0.025 13.9 0.0 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGG10047.1 - 0.011 15.0 1.9 0.44 9.7 0.4 2.8 3 0 0 3 3 3 0 Thi4 family FAD_binding_2 PF00890.24 EGG10047.1 - 0.011 14.8 0.3 0.011 14.8 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 EGG10047.1 - 0.046 13.8 0.1 25 4.9 0.1 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EGG10047.1 - 0.21 10.3 6.3 0.087 11.5 1.0 2.1 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 EGG10047.1 - 2.4 7.2 6.5 0.47 9.5 0.3 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ATPase PF06745.13 EGG10048.1 - 0.15 11.4 1.2 0.25 10.6 1.2 1.3 1 0 0 1 1 1 0 KaiC zf-HC5HC2H PF13771.6 EGG10052.1 - 0.015 15.5 3.0 0.039 14.2 3.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-C2H2_4 PF13894.6 EGG10052.1 - 0.03 15.1 6.8 3.1 8.9 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger PAH PF02671.21 EGG10052.1 - 0.11 12.7 1.7 12 6.2 0.0 3.3 3 1 0 3 3 3 0 Paired amphipathic helix repeat zf-C2H2 PF00096.26 EGG10052.1 - 0.22 12.0 7.8 0.33 11.5 0.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type HECA PF15353.6 EGG10052.1 - 0.28 11.4 4.5 0.77 10.0 0.5 2.4 1 1 1 2 2 2 0 Headcase protein family homologue Ctr PF04145.15 EGG10054.1 - 1.8e-28 100.0 0.0 2.2e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family UCR_UQCRX_QCR9 PF05365.12 EGG10054.1 - 0.088 12.8 1.9 0.15 12.0 1.9 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF5489 PF17592.2 EGG10054.1 - 1.9 9.1 6.1 0.28 11.7 2.3 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5489) ssDNA_DBD PF18333.1 EGG10055.1 - 0.076 13.1 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Non-canonical single-stranded DNA-binding domain F-box PF00646.33 EGG10055.1 - 0.094 12.6 1.1 0.25 11.3 1.1 1.8 1 0 0 1 1 1 0 F-box domain Vac14_Fig4_bd PF11916.8 EGG10056.1 - 3.9e-74 248.2 5.1 7.8e-74 247.2 5.1 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EGG10056.1 - 3e-37 127.1 0.1 8.3e-35 119.3 0.0 3.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGG10056.1 - 1.5e-06 28.0 0.0 0.024 14.9 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EGG10056.1 - 0.0002 21.4 3.1 0.13 12.3 0.0 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGG10056.1 - 0.0012 19.2 0.1 4.9 7.6 0.0 3.7 4 0 0 4 4 4 2 HEAT repeats MMS19_C PF12460.8 EGG10056.1 - 0.0022 17.2 5.2 0.46 9.5 0.2 3.5 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 EGG10056.1 - 0.0056 17.2 0.1 6.8 7.3 0.0 4.3 3 1 1 4 4 4 1 HEAT-like repeat ParcG PF10274.9 EGG10056.1 - 0.2 11.8 1.6 6.5 6.8 0.0 3.3 4 0 0 4 4 4 0 Parkin co-regulated protein RecO_C PF02565.15 EGG10056.1 - 7 6.4 6.4 0.68 9.7 0.2 2.4 3 0 0 3 3 3 0 Recombination protein O C terminal Clathrin_lg_ch PF01086.17 EGG10062.1 - 1e-59 202.4 4.2 1.2e-59 202.2 4.2 1.0 1 0 0 1 1 1 1 Clathrin light chain Ham1p_like PF01725.16 EGG10064.1 - 5.5e-56 189.5 0.0 6.2e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family ArsA_ATPase PF02374.15 EGG10064.1 - 0.0069 15.6 0.1 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase RCC1 PF00415.18 EGG10065.1 - 3.5e-22 78.8 0.6 0.13 12.9 0.0 8.6 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG10065.1 - 1.5e-14 53.3 11.7 6.7e-09 35.3 0.6 5.9 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat ThiG PF05690.14 EGG10065.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Pterin_bind PF00809.22 EGG10066.1 - 3.7e-79 265.9 0.2 5.5e-79 265.3 0.2 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EGG10066.1 - 3.5e-33 114.5 0.0 7.4e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 EGG10066.1 - 1.2e-24 87.0 0.0 1.6e-21 77.0 0.0 2.6 2 0 0 2 2 2 2 Dihydroneopterin aldolase T6SS_TssF PF05947.12 EGG10066.1 - 0.048 12.2 0.0 0.13 10.7 0.0 1.6 2 0 0 2 2 2 0 Type VI secretion system, TssF DUF711 PF05167.12 EGG10066.1 - 0.091 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) Ceramidase PF05875.12 EGG10067.1 - 5.1e-86 288.4 4.9 6.1e-86 288.1 4.9 1.0 1 0 0 1 1 1 1 Ceramidase TCR_zetazeta PF11628.8 EGG10067.1 - 0.015 15.0 0.5 0.015 15.0 0.5 1.9 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain CPSase_L_D2 PF02786.17 EGG10068.1 - 2e-110 367.3 0.1 4.5e-84 281.2 0.0 2.5 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EGG10068.1 - 1.2e-39 135.4 0.1 4.1e-39 133.7 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EGG10068.1 - 3.7e-16 59.2 0.0 5.8e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGG10068.1 - 2.5e-13 50.1 0.1 3.9e-05 23.3 0.1 3.0 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EGG10068.1 - 1.4e-12 47.5 0.0 4.9e-06 26.3 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 EGG10068.1 - 4.3e-05 23.1 0.1 0.24 10.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 EGG10068.1 - 0.00029 20.5 0.0 1 8.9 0.0 3.1 2 1 0 2 2 2 2 RimK-like ATP-grasp domain MGS PF02142.22 EGG10068.1 - 0.017 15.3 0.0 0.21 11.8 0.0 2.9 2 1 0 2 2 2 0 MGS-like domain Peptidase_M17_N PF02789.17 EGG10068.1 - 0.063 13.1 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Sel1 PF08238.12 EGG10070.1 - 3e-26 91.2 28.7 0.00015 22.3 0.0 10.5 10 1 0 10 10 10 7 Sel1 repeat TPR_1 PF00515.28 EGG10070.1 - 0.00053 19.7 5.0 0.84 9.6 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG10070.1 - 0.00096 19.1 5.6 0.73 10.1 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG10070.1 - 0.14 12.8 0.0 0.14 12.8 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGG10070.1 - 6.1 7.3 7.0 24 5.5 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Ribosomal_S15 PF00312.22 EGG10071.1 - 2.1e-15 56.7 0.2 2.1e-15 56.7 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 KDZ PF18758.1 EGG10072.1 - 5.5e-38 130.8 0.1 2e-37 129.0 0.0 1.8 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase Ribonuc_red_2_N PF08471.10 EGG10074.1 - 0.012 15.7 0.1 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase Abhydrolase_3 PF07859.13 EGG10077.1 - 3.1e-05 23.9 0.0 6.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold IQ PF00612.27 EGG10077.1 - 0.14 12.0 0.3 0.38 10.7 0.3 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif APG5 PF04106.12 EGG10078.1 - 2.8e-60 203.7 0.0 3.6e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Retrotran_gag_2 PF14223.6 EGG10079.1 - 1.1e-11 44.5 0.0 1.7e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type ADH_N PF08240.12 EGG10083.1 - 1.5e-24 86.0 1.6 3.4e-24 84.8 1.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGG10083.1 - 1.2e-15 57.6 0.0 1.8e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGG10083.1 - 2.1e-05 24.1 0.2 0.00028 20.4 0.2 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGG10083.1 - 0.13 13.3 0.0 0.25 12.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1918 PF08940.11 EGG10083.1 - 0.38 10.4 3.4 0.34 10.6 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) 5-FTHF_cyc-lig PF01812.20 EGG10084.1 - 1.6e-38 132.4 0.0 1.9e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Leo1 PF04004.13 EGG10085.1 - 3.6e-42 144.0 1.1 3.6e-42 144.0 1.1 3.1 3 1 0 3 3 3 1 Leo1-like protein DUF5392 PF17370.2 EGG10086.1 - 0.049 13.7 0.4 0.081 13.0 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5392) DUF737 PF05300.11 EGG10086.1 - 1.9 8.8 9.6 6.1 7.2 9.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF737) Pkinase PF00069.25 EGG10087.1 - 5.4e-62 209.5 0.5 6.3e-62 209.3 0.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG10087.1 - 1.4e-36 126.1 0.0 1.7e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG10087.1 - 0.00014 20.9 4.3 0.00029 19.9 4.3 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGG10087.1 - 0.00072 18.9 0.0 0.0039 16.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EGG10087.1 - 0.0014 17.7 0.7 0.0051 15.9 0.1 1.9 1 1 1 2 2 2 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EGG10087.1 - 0.0019 17.0 0.2 0.006 15.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 EGG10087.1 - 0.0023 17.6 0.6 0.49 10.0 0.0 2.2 1 1 1 2 2 2 2 RIO1 family APH PF01636.23 EGG10087.1 - 0.0049 16.8 0.0 0.045 13.7 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family MutS_IV PF05190.18 EGG10087.1 - 0.065 13.6 0.2 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 MutS family domain IV PK PF00224.21 EGG10088.1 - 2.1e-158 526.7 0.7 2.7e-158 526.4 0.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGG10088.1 - 1.8e-34 118.4 0.1 3.7e-34 117.4 0.1 1.5 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGG10088.1 - 0.011 14.9 0.4 0.029 13.5 0.4 1.7 1 1 1 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family zf-RING_UBOX PF13445.6 EGG10091.1 - 9.3e-07 28.8 6.3 1.9e-06 27.8 6.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG10091.1 - 4.3e-06 26.6 7.9 1.2e-05 25.1 7.9 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGG10091.1 - 0.00024 21.3 7.0 0.00063 20.0 7.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGG10091.1 - 0.00065 19.5 4.1 0.0016 18.2 4.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGG10091.1 - 0.0043 17.2 7.1 0.025 14.7 7.2 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Dynamitin PF04912.14 EGG10091.1 - 0.0069 15.8 5.9 0.0098 15.3 5.9 1.1 1 0 0 1 1 1 1 Dynamitin zf-C3HC4_2 PF13923.6 EGG10091.1 - 0.0079 16.0 4.6 0.033 14.1 4.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG10091.1 - 0.011 15.6 1.1 0.011 15.6 1.1 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.21 EGG10091.1 - 0.013 15.7 5.3 0.038 14.1 5.3 1.8 1 0 0 1 1 1 0 FYVE zinc finger JIP_LZII PF16471.5 EGG10091.1 - 0.015 15.5 8.6 0.86 9.8 2.1 2.6 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Herpes_UL25 PF01499.16 EGG10091.1 - 0.015 13.9 1.3 0.022 13.3 1.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family HAUS-augmin3 PF14932.6 EGG10091.1 - 0.015 14.8 6.1 0.025 14.2 6.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Seryl_tRNA_N PF02403.22 EGG10091.1 - 0.02 15.1 5.1 0.02 15.1 5.1 1.8 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain zf-C4H2 PF10146.9 EGG10091.1 - 0.022 15.1 5.4 0.053 13.8 5.4 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein ZapB PF06005.12 EGG10091.1 - 0.045 14.2 14.8 0.42 11.1 6.6 2.5 1 1 1 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 EGG10091.1 - 0.053 13.3 9.1 1.4 8.7 3.0 2.9 2 1 1 3 3 3 0 Septum formation initiator zf-C3HC4_3 PF13920.6 EGG10091.1 - 0.085 12.7 6.5 0.23 11.4 6.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RAP1 PF07218.11 EGG10091.1 - 0.086 11.1 9.3 0.11 10.8 9.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Bap31_Bap29_C PF18035.1 EGG10091.1 - 0.096 12.7 1.5 0.53 10.3 0.1 2.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain bZIP_Maf PF03131.17 EGG10091.1 - 0.097 13.2 6.8 4.3 7.9 2.5 2.7 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF948 PF06103.11 EGG10091.1 - 0.11 12.7 2.8 1.7 8.9 2.6 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) KASH_CCD PF14662.6 EGG10091.1 - 0.12 12.1 13.3 0.24 11.2 13.3 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DWNN PF08783.11 EGG10091.1 - 0.13 12.6 0.3 2.9 8.2 0.0 2.4 2 0 0 2 2 2 0 DWNN domain Serine_rich PF08824.10 EGG10091.1 - 0.16 11.9 1.9 0.3 11.1 1.9 1.5 1 0 0 1 1 1 0 Serine rich protein interaction domain Phage_GP20 PF06810.11 EGG10091.1 - 0.17 11.7 5.5 0.32 10.8 5.4 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 Ten1_2 PF15490.6 EGG10091.1 - 0.17 11.6 0.5 1 9.1 0.5 2.1 2 1 0 2 2 2 0 Telomere-capping, CST complex subunit Suppressor_APC PF11414.8 EGG10091.1 - 0.21 11.7 6.8 2.9 8.0 0.2 2.4 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein FapA PF03961.13 EGG10091.1 - 0.23 10.1 5.3 0.34 9.5 5.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 EGG10091.1 - 0.26 11.8 10.2 0.54 10.8 10.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 EGG10091.1 - 0.53 10.4 9.6 0.91 9.6 9.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 EGG10091.1 - 0.79 9.7 14.3 1.6 8.7 14.3 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.18 EGG10091.1 - 0.85 10.0 10.2 27 5.1 0.8 3.5 1 1 2 3 3 3 0 TSC-22/dip/bun family ATG16 PF08614.11 EGG10091.1 - 0.86 9.8 10.8 0.88 9.8 9.8 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) THOC7 PF05615.13 EGG10091.1 - 1.3 9.3 10.1 83 3.5 9.9 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 EGG10091.1 - 3.3 7.8 14.0 3.9 7.6 11.4 2.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Tmemb_cc2 PF10267.9 EGG10091.1 - 3.6 6.6 14.1 2.6 7.1 11.9 1.7 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein SlyX PF04102.12 EGG10091.1 - 4.4 8.0 8.7 5.2 7.8 5.0 2.7 2 1 1 3 3 3 0 SlyX Uso1_p115_C PF04871.13 EGG10091.1 - 4.9 7.5 11.8 0.88 9.9 8.1 1.6 2 0 0 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Syntaxin-6_N PF09177.11 EGG10091.1 - 5.6 7.6 8.9 0.58 10.7 0.2 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.19 EGG10091.1 - 6.8 4.5 6.8 9.7 4.0 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 EGG10091.1 - 6.9 5.8 8.0 11 5.2 8.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein TMF_TATA_bd PF12325.8 EGG10091.1 - 7.2 6.9 12.0 11 6.2 7.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 EGG10091.1 - 7.9 6.5 7.8 2.7 8.0 3.1 2.4 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) UXS1_N PF11803.8 EGG10095.1 - 4.2e-05 23.8 7.0 41 4.7 0.0 8.0 8 0 0 8 8 8 0 UDP-glucuronate decarboxylase N-terminal Ub-Mut7C PF14451.6 EGG10095.1 - 0.0012 18.7 3.1 4.9 7.1 0.0 5.2 4 1 1 5 5 5 2 Mut7-C ubiquitin DUF2200 PF09966.9 EGG10095.1 - 0.0026 17.9 0.7 39 4.4 0.0 5.5 6 1 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2200) CAP_N PF01213.19 EGG10095.1 - 0.0051 16.3 16.1 0.19 11.2 0.2 4.7 1 1 2 4 4 4 2 Adenylate cyclase associated (CAP) N terminal HEAT_2 PF13646.6 EGG10095.1 - 0.017 15.5 0.1 3.6 8.1 0.0 3.5 3 2 0 3 3 3 0 HEAT repeats Interferon PF00143.19 EGG10095.1 - 0.042 14.0 28.5 6.8 6.8 0.0 8.3 5 3 4 9 9 9 0 Interferon alpha/beta domain MSP PF01716.18 EGG10095.1 - 0.067 12.4 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide DUF5595 PF18077.1 EGG10095.1 - 0.19 11.8 1.4 1.6 8.9 0.4 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) KASH_CCD PF14662.6 EGG10095.1 - 7 6.4 18.5 0.071 12.9 5.5 3.2 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Aldo_ket_red PF00248.21 EGG10099.1 - 1.1e-42 146.3 0.0 2.7e-40 138.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF3987 PF13148.6 EGG10102.1 - 0.024 13.6 4.0 0.027 13.5 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) PTS_IIA PF02255.16 EGG10102.1 - 0.026 14.5 1.2 0.031 14.3 0.4 1.5 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Elf1 PF05129.13 EGG10103.1 - 0.043 13.9 2.2 0.05 13.6 2.2 1.1 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like CcmH PF03918.14 EGG10103.1 - 0.13 11.6 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Ifi-6-16 PF06140.13 EGG10105.1 - 1.3e-10 41.1 14.3 1.5e-10 40.9 14.3 1.1 1 0 0 1 1 1 1 Interferon-induced 6-16 family TFIID_30kDa PF03540.13 EGG10106.1 - 3.3e-23 81.4 0.1 6.8e-23 80.4 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 EGG10106.1 - 0.00097 19.1 0.0 0.065 13.2 0.0 2.2 2 0 0 2 2 2 2 Bromodomain associated Hydrolase_6 PF13344.6 EGG10109.1 - 1.6e-30 105.1 0.0 3e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGG10109.1 - 2e-19 69.4 0.0 5.8e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EGG10109.1 - 2e-09 38.0 0.0 3.4e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGG10109.1 - 7.1e-08 32.7 0.0 0.0082 16.2 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF4070 PF13282.6 EGG10109.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) EVE PF01878.18 EGG10110.1 - 1.8e-41 141.5 0.0 4.6e-41 140.2 0.0 1.6 1 1 0 1 1 1 1 EVE domain Response_reg PF00072.24 EGG10111.1 - 1.9e-48 163.3 0.4 8.3e-27 93.6 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 EGG10111.1 - 2.3e-39 134.3 0.1 3.3e-19 69.5 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG10111.1 - 5.3e-18 64.8 0.3 3.6e-11 42.9 0.1 3.1 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 EGG10111.1 - 1.1e-08 35.3 0.0 2.7e-06 27.6 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 EGG10111.1 - 0.00011 22.4 1.1 0.00074 19.8 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 EGG10111.1 - 0.00013 22.0 0.3 0.00059 19.8 0.0 2.2 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 EGG10111.1 - 0.008 16.0 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 EGG10111.1 - 0.019 15.2 0.2 0.079 13.2 0.0 2.2 2 0 0 2 2 2 0 PAS domain HATPase_c_5 PF14501.6 EGG10111.1 - 0.046 13.6 0.0 1.6 8.7 0.0 2.7 2 0 0 2 2 2 0 GHKL domain GAF_2 PF13185.6 EGG10111.1 - 0.11 12.8 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 GAF domain PAS_8 PF13188.7 EGG10111.1 - 0.14 12.2 0.0 0.58 10.3 0.0 2.1 1 0 0 1 1 1 0 PAS domain CAF20 PF17052.5 EGG10111.1 - 0.17 12.0 1.1 5.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Cap associated factor zf-RING_13 PF17977.1 EGG10112.1 - 0.011 15.8 4.6 0.02 15.0 2.4 2.6 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Hanta_nucleocap PF00846.18 EGG10112.1 - 0.12 10.7 0.0 3.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Hantavirus nucleocapsid protein IF4E PF01652.18 EGG10113.1 - 3.3e-53 179.8 1.3 3.8e-53 179.5 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SAP30_Sin3_bdg PF13867.6 EGG10113.1 - 0.12 12.7 0.0 0.73 10.2 0.0 2.0 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DsbC PF11412.8 EGG10113.1 - 0.15 12.1 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Disulphide bond corrector protein DsbC bZIP_2 PF07716.15 EGG10114.1 - 0.00013 21.9 15.4 0.00013 21.9 15.4 2.3 2 0 0 2 2 2 1 Basic region leucine zipper Caskin-tail PF16632.5 EGG10114.1 - 0.017 15.5 0.1 0.072 13.5 0.1 2.2 1 0 0 1 1 1 0 C-terminal region of Caskin DUF1978 PF09321.10 EGG10114.1 - 0.054 12.8 4.2 0.11 11.8 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) bZIP_C PF12498.8 EGG10114.1 - 0.27 12.2 0.2 0.27 12.2 0.2 3.0 2 1 1 3 3 3 0 Basic leucine-zipper C terminal Csm1_N PF18504.1 EGG10114.1 - 0.3 11.4 0.2 0.3 11.4 0.2 2.8 3 0 0 3 3 3 0 Csm1 N-terminal domain bZIP_1 PF00170.21 EGG10114.1 - 0.34 11.0 20.0 5.1 7.3 14.6 2.8 3 0 0 3 3 3 0 bZIP transcription factor DUF3450 PF11932.8 EGG10114.1 - 2.1 7.6 8.1 0.34 10.2 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FapA PF03961.13 EGG10114.1 - 5.5 5.5 4.5 7.7 5.0 4.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5446 PF17522.2 EGG10114.1 - 6.1 7.1 6.6 0.99 9.6 2.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5446) FAD_binding_3 PF01494.19 EGG10115.1 - 7.2e-14 51.8 0.0 8.7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain 7TMR-HDED PF07697.11 EGG10118.1 - 0.0039 17.4 1.8 0.27 11.3 0.2 2.2 2 0 0 2 2 2 2 7TM-HD extracellular FAD_binding_3 PF01494.19 EGG10120.1 - 1.7e-47 162.4 0.0 2.4e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EGG10120.1 - 4.9e-05 22.7 0.0 7.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EGG10120.1 - 0.0001 21.5 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 EGG10120.1 - 0.0005 19.8 0.1 0.00077 19.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGG10120.1 - 0.0015 18.7 0.0 0.0052 17.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGG10120.1 - 0.0033 17.4 0.1 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGG10120.1 - 0.0082 15.4 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGG10120.1 - 0.017 14.2 0.0 0.054 12.6 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 EGG10120.1 - 0.03 14.9 0.0 0.11 13.0 0.0 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EGG10120.1 - 0.12 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pkinase PF00069.25 EGG10121.1 - 1.2e-72 244.5 0.0 1.5e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG10121.1 - 4.1e-37 127.9 0.0 5.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EGG10121.1 - 7.9e-23 81.2 0.0 1.7e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 EGG10121.1 - 1.7e-08 34.1 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YukC PF10140.9 EGG10121.1 - 0.0042 16.0 0.2 0.0058 15.5 0.2 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 EGG10121.1 - 0.03 13.3 0.2 0.043 12.8 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PseudoU_synth_2 PF00849.22 EGG10122.1 - 2e-23 83.2 0.0 3.1e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Proteasome PF00227.26 EGG10123.1 - 1.7e-48 164.6 0.0 2.2e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EGG10123.1 - 4.9e-10 38.6 0.0 4.9e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal BLOC1_2 PF10046.9 EGG10125.1 - 0.021 15.1 3.0 0.92 9.8 0.6 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 EGG10125.1 - 0.043 14.2 4.8 2.3 8.6 0.6 2.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 EGG10125.1 - 0.066 13.8 5.2 0.24 12.0 2.0 3.1 2 1 0 2 2 2 0 SlyX Lzipper-MIP1 PF14389.6 EGG10125.1 - 0.14 12.5 5.3 5 7.5 0.6 3.1 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 TMCO5 PF14992.6 EGG10125.1 - 0.46 10.0 6.5 0.63 9.6 5.4 1.7 1 1 0 1 1 1 0 TMCO5 family Tropomyosin_1 PF12718.7 EGG10125.1 - 0.56 10.4 9.1 1.3 9.1 1.4 3.0 2 1 1 3 3 3 0 Tropomyosin like FlaC_arch PF05377.11 EGG10125.1 - 3.1 8.3 7.1 8.6 6.8 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CxC1 PF18802.1 EGG10126.1 - 3.6e-21 75.3 0.5 4.3e-20 71.8 0.5 2.4 1 1 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG10126.1 - 2.7e-06 27.5 0.1 5.7e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG10126.1 - 0.016 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases DUF2477 PF10631.9 EGG10127.1 - 0.032 14.9 0.1 0.071 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) FAM60A PF15396.6 EGG10129.1 - 0.063 13.3 2.9 0.12 12.4 2.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_S49_N PF08496.10 EGG10129.1 - 7.1 6.7 10.8 12 5.9 10.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF5136 PF17199.4 EGG10130.1 - 1 9.1 4.7 1.7 8.4 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF5136) zf-CCHC_2 PF13696.6 EGG10132.1 - 0.00088 19.0 4.3 0.0017 18.2 4.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGG10132.1 - 0.0029 17.6 2.6 0.0047 16.9 2.6 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGG10132.1 - 0.23 11.5 1.3 0.5 10.4 1.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Big_7 PF17957.1 EGG10133.1 - 0.028 15.2 4.2 0.061 14.1 4.2 1.6 1 1 0 1 1 1 0 Bacterial Ig domain RELT PF12606.8 EGG10134.1 - 1.2 8.1 5.5 0.72 8.9 0.7 2.3 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Ribosomal_L7Ae PF01248.26 EGG10135.1 - 2.1e-19 69.0 0.1 2.7e-19 68.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DNA_photolyase PF00875.18 EGG10135.1 - 0.054 13.5 0.0 0.078 13.0 0.0 1.3 1 1 0 1 1 1 0 DNA photolyase DUF374 PF04028.13 EGG10135.1 - 0.14 11.8 0.3 1.9 8.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF374) 14-3-3 PF00244.20 EGG10136.1 - 3.5e-107 357.0 1.5 4.2e-107 356.7 1.5 1.1 1 0 0 1 1 1 1 14-3-3 protein STT3 PF02516.14 EGG10138.1 - 0.045 12.7 6.0 0.062 12.2 6.0 1.1 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit TSP_NTD PF17804.1 EGG10138.1 - 0.096 12.9 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Ras PF00071.22 EGG10139.1 - 5.5e-54 182.1 0.1 6.3e-54 181.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG10139.1 - 6.3e-30 103.9 0.0 8.7e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG10139.1 - 3.6e-14 52.6 0.0 4.7e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG10139.1 - 1.3e-06 28.5 0.0 4e-06 26.9 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG10139.1 - 2e-05 24.3 0.0 6.4e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGG10139.1 - 0.0004 19.8 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGG10139.1 - 0.00053 19.5 0.0 0.00091 18.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EGG10139.1 - 0.0012 18.7 0.0 0.0018 18.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGG10139.1 - 0.0063 16.4 0.2 0.24 11.3 0.1 2.4 2 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGG10139.1 - 0.075 13.4 0.1 0.13 12.6 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Spt5-NGN PF03439.13 EGG10140.1 - 2.7e-25 88.1 0.0 4.7e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EGG10140.1 - 4.7e-24 85.2 9.2 4.7e-24 85.2 9.2 2.7 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EGG10140.1 - 7.1e-20 70.2 5.9 0.00051 19.9 0.2 6.9 6 0 0 6 6 6 5 KOW motif CTD PF12815.7 EGG10140.1 - 0.00027 21.4 12.3 0.00027 21.4 12.3 4.8 1 1 2 3 3 3 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Ribosomal_L31e PF01198.19 EGG10141.1 - 4.2e-43 145.5 0.7 5.4e-43 145.1 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 EGG10141.1 - 0.019 15.0 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Cyclin_N PF00134.23 EGG10142.1 - 2.4e-35 121.1 0.1 5.1e-35 120.0 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGG10142.1 - 5.2e-07 29.8 0.0 9.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain LSM PF01423.22 EGG10144.1 - 1.9e-16 59.5 0.2 2.4e-16 59.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGG10144.1 - 0.037 13.7 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Glyco_hydro_26 PF02156.15 EGG10145.1 - 0.048 13.1 0.6 0.054 12.9 0.6 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 26 Rad60-SLD PF11976.8 EGG10146.1 - 2.4e-14 52.9 0.0 3e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGG10146.1 - 6e-08 32.3 0.0 7.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBX PF00789.20 EGG10146.1 - 0.098 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 UBX domain Ubiquitin_4 PF18036.1 EGG10146.1 - 0.16 12.0 0.0 2.7 8.1 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain YjeF_N PF03853.15 EGG10147.1 - 7.4e-37 126.9 0.0 8.6e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.25 EGG10147.1 - 0.025 14.0 0.0 0.032 13.6 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme MAGE PF01454.19 EGG10147.1 - 0.05 13.3 0.1 0.07 12.8 0.1 1.2 1 0 0 1 1 1 0 MAGE family Amino_oxidase PF01593.24 EGG10147.1 - 0.25 10.6 0.1 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lipase_3 PF01764.25 EGG10148.1 - 5.6e-17 61.9 0.0 1.3e-16 60.7 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) DUF5527 PF17665.1 EGG10150.1 - 1.2 8.7 3.0 5.1 6.6 0.2 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5527) Fibrillin_U_N PF18193.1 EGG10152.1 - 0.084 13.0 0.4 0.084 13.0 0.4 1.6 2 0 0 2 2 2 0 Fibrillin 1 unique N-terminal domain ThiI PF02568.14 EGG10152.1 - 0.1 12.2 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Nop53 PF07767.11 EGG10153.1 - 0.057 12.8 11.4 0.076 12.4 11.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SRP54 PF00448.22 EGG10154.1 - 4.2e-75 251.7 0.2 4.2e-75 251.7 0.2 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EGG10154.1 - 7.6e-31 106.7 1.1 7.6e-31 106.7 1.1 3.4 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 EGG10154.1 - 7.6e-17 61.3 0.6 1.8e-16 60.1 0.6 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EGG10154.1 - 6.2e-06 25.9 0.1 4.1e-05 23.2 0.1 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EGG10154.1 - 3.2e-05 23.0 4.8 0.004 16.2 0.0 3.5 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EGG10154.1 - 3.7e-05 23.9 0.4 0.0002 21.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EGG10154.1 - 0.00023 21.2 0.0 0.00061 19.8 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EGG10154.1 - 0.0023 18.3 0.7 0.0053 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 EGG10154.1 - 0.0048 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 EGG10154.1 - 0.005 16.1 0.0 0.014 14.7 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin SRPRB PF09439.10 EGG10154.1 - 0.017 14.5 0.3 3.1 7.2 0.0 3.0 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 EGG10154.1 - 0.019 14.8 0.2 0.19 11.5 0.1 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ArsA_ATPase PF02374.15 EGG10154.1 - 0.019 14.1 0.0 2.7 7.1 0.0 2.6 2 0 0 2 2 2 0 Anion-transporting ATPase Rbsn PF11464.8 EGG10154.1 - 0.035 13.8 0.2 0.2 11.4 0.2 2.4 1 0 0 1 1 1 0 Rabenosyn Rab binding domain MobB PF03205.14 EGG10154.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 EGG10154.1 - 0.037 14.3 0.1 0.21 11.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 EGG10154.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.6 EGG10154.1 - 0.074 13.3 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGG10154.1 - 0.075 13.5 1.0 0.35 11.3 0.2 2.7 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 EGG10154.1 - 0.077 13.0 0.1 1.7 8.6 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGG10154.1 - 0.18 12.1 4.3 2.3 8.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain Sec66 PF09802.9 EGG10155.1 - 1.2e-45 155.3 0.0 2.1e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4653 PF15546.6 EGG10155.1 - 0.18 11.4 6.9 1.2 8.7 6.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4653) SQS_PSY PF00494.19 EGG10156.1 - 1.6e-41 142.6 0.0 3.3e-41 141.5 0.0 1.5 1 1 0 1 1 1 1 Squalene/phytoene synthase C1_2 PF03107.16 EGG10157.1 - 0.057 13.7 6.7 0.21 11.9 0.8 2.7 2 0 0 2 2 2 0 C1 domain Rad60-SLD_2 PF13881.6 EGG10158.1 - 0.00038 20.5 0.0 0.00093 19.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGG10158.1 - 0.0055 17.2 0.0 0.026 15.1 0.0 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Peptidase_M36 PF02128.15 EGG10159.1 - 1.7e-155 517.8 0.6 2.6e-155 517.2 0.6 1.3 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 EGG10159.1 - 0.021 14.7 0.0 0.065 13.1 0.0 1.8 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Rad21_Rec8_N PF04825.13 EGG10161.1 - 5.8e-31 106.9 0.0 1.1e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGG10161.1 - 5.8e-13 47.9 0.0 1.2e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein PLDc PF00614.22 EGG10162.1 - 4.8e-16 58.2 3.7 4.9e-10 39.2 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGG10162.1 - 3.2e-15 56.2 0.0 7.1e-07 29.2 0.0 3.7 4 0 0 4 4 4 2 PLD-like domain Amidohydro_2 PF04909.14 EGG10163.1 - 7.4e-07 29.2 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 EGG10163.1 - 0.00064 19.1 0.0 0.0012 18.3 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family DUF3018 PF11455.8 EGG10164.1 - 0.13 12.2 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) Atx10homo_assoc PF09759.9 EGG10166.1 - 4.6e-14 52.2 0.1 4.6e-14 52.2 0.1 1.9 2 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Arf PF00025.21 EGG10167.1 - 5e-21 74.9 0.1 6.7e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGG10167.1 - 1.4e-08 34.3 1.0 9.8e-06 25.0 0.1 2.0 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGG10167.1 - 3.3e-05 23.4 0.0 4.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGG10167.1 - 0.00072 19.8 0.0 0.00097 19.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGG10167.1 - 0.00096 18.6 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG10167.1 - 0.00097 19.2 0.0 0.0012 18.9 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 EGG10167.1 - 0.012 15.1 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Thymidylate_kin PF02223.17 EGG10167.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase AAA_29 PF13555.6 EGG10167.1 - 0.031 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGG10167.1 - 0.042 14.1 0.0 0.057 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG10167.1 - 0.065 13.6 0.0 0.067 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 EGG10167.1 - 0.084 12.9 0.1 0.1 12.6 0.1 1.3 1 1 0 1 1 1 0 AAA domain DLIC PF05783.11 EGG10167.1 - 0.088 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) FtsK_SpoIIIE PF01580.18 EGG10167.1 - 0.18 11.1 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family Thioredoxin_8 PF13905.6 EGG10168.1 - 5e-10 39.6 1.2 2e-09 37.6 0.6 2.1 2 0 0 2 2 2 1 Thioredoxin-like Tryp_alpha_amyl PF00234.22 EGG10170.1 - 0.096 13.1 1.1 0.31 11.5 1.1 2.0 1 1 0 1 1 1 0 Protease inhibitor/seed storage/LTP family Pox_A12 PF04651.13 EGG10171.1 - 3.4 7.7 12.1 6.2 6.8 12.1 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein Macoilin PF09726.9 EGG10171.1 - 4.2 5.8 10.5 5.2 5.5 10.5 1.1 1 0 0 1 1 1 0 Macoilin family Nucleoporin2 PF04096.14 EGG10172.1 - 0.021 14.9 0.1 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin autopeptidase WD40 PF00400.32 EGG10173.1 - 7.8e-43 143.6 14.1 3.4e-09 37.2 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG10173.1 - 2.4e-19 69.4 1.0 0.0049 17.1 0.0 6.0 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG10173.1 - 3.2e-07 30.4 2.3 0.0012 18.8 0.0 3.7 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGG10173.1 - 3.1e-06 26.1 5.3 0.16 10.6 0.1 4.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGG10173.1 - 3.7e-06 26.1 4.0 0.18 10.8 0.2 4.5 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGG10173.1 - 2.1e-05 24.0 1.3 0.17 11.2 0.0 3.5 2 1 2 4 4 4 3 WD40-like domain Utp8 PF10395.9 EGG10173.1 - 0.00015 20.4 3.1 0.033 12.7 0.0 2.3 1 1 0 2 2 2 2 Utp8 family Cytochrom_D1 PF02239.16 EGG10173.1 - 0.046 12.2 0.0 1.4 7.4 0.0 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain CxC1 PF18802.1 EGG10175.1 - 1.1e-22 80.1 0.1 2e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG10175.1 - 0.00032 20.8 0.0 0.00082 19.5 0.0 1.7 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases VHL PF01847.16 EGG10175.1 - 0.052 13.5 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 VHL beta domain KDZ PF18758.1 EGG10175.1 - 0.087 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase Hairy_orange PF07527.13 EGG10176.1 - 0.074 13.3 0.2 6.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Hairy Orange DPPIV_rep PF18811.1 EGG10176.1 - 0.1 12.6 0.1 0.29 11.1 0.1 1.8 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) low complexity region AP3D1 PF06375.11 EGG10178.1 - 0.35 11.1 17.1 0.36 11.1 12.8 2.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Presenilin PF01080.17 EGG10178.1 - 0.39 9.4 2.9 0.66 8.7 2.9 1.3 1 0 0 1 1 1 0 Presenilin GST_N_3 PF13417.6 EGG10179.1 - 9.2e-09 35.6 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGG10179.1 - 4.1e-07 30.2 0.0 8.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGG10179.1 - 0.00013 22.2 0.0 0.00031 21.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGG10179.1 - 0.0012 18.8 0.0 0.014 15.4 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG10179.1 - 0.0081 16.3 0.1 0.024 14.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG10179.1 - 0.028 14.6 0.0 0.083 13.1 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Gti1_Pac2 PF09729.9 EGG10180.1 - 1.7e-58 197.7 1.3 1.7e-58 197.7 1.3 3.3 3 2 0 3 3 3 1 Gti1/Pac2 family Pept_tRNA_hydro PF01195.19 EGG10181.1 - 7.7e-15 55.3 0.0 9.1e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Cadherin-like PF12733.7 EGG10182.1 - 0.012 16.2 0.2 0.03 14.8 0.2 1.7 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain Nup84_Nup100 PF04121.13 EGG10185.1 - 4.2e-150 501.3 3.1 2.6e-127 425.9 0.8 2.1 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 DUF4034 PF13226.6 EGG10185.1 - 0.0041 16.5 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4034) PMI_typeI PF01238.21 EGG10186.1 - 8e-118 393.9 0.0 1.1e-117 393.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 EGG10186.1 - 0.025 14.5 0.1 14 5.5 0.0 3.1 4 0 0 4 4 4 0 AraC-like ligand binding domain Antimicrobial_2 PF08023.12 EGG10186.1 - 0.1 13.1 0.0 0.3 11.6 0.0 1.8 2 0 0 2 2 2 0 Frog antimicrobial peptide Brix PF04427.18 EGG10187.1 - 5e-33 114.8 0.0 6.5e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain UbiA PF01040.18 EGG10188.1 - 1.3e-23 83.6 0.6 1.4e-23 83.5 0.6 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Peptidase_S80 PF07230.11 EGG10196.1 - 0.13 10.5 0.1 0.17 10.2 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) DUF4611 PF15387.6 EGG10196.1 - 1.8 8.8 6.4 0.48 10.7 3.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PADR1 PF08063.12 EGG10199.1 - 0.085 12.6 1.7 0.18 11.6 1.7 1.5 1 0 0 1 1 1 0 PADR1 (NUC008) domain ANAPC2 PF08672.11 EGG10200.1 - 0.023 15.2 0.1 0.039 14.5 0.1 1.4 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 UBN_AB PF14075.6 EGG10200.1 - 0.028 14.1 7.4 0.031 14.0 7.4 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain PBP_sp32 PF07222.12 EGG10200.1 - 0.31 10.4 14.4 0.38 10.2 14.4 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 V_ATPase_I PF01496.19 EGG10200.1 - 0.35 8.7 6.0 0.37 8.7 6.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Merozoite_SPAM PF07133.11 EGG10200.1 - 1.3 9.0 31.7 1.8 8.5 31.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CCDC53 PF10152.9 EGG10200.1 - 2.7 8.4 11.3 2.7 8.4 10.5 1.3 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex TRAP_alpha PF03896.16 EGG10200.1 - 5.5 6.1 8.9 8.1 5.6 8.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Kelch_1 PF01344.25 EGG10202.1 - 7.4e-07 28.7 0.0 9.2e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.6 EGG10202.1 - 7.8e-06 25.8 0.0 9.1e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.6 EGG10202.1 - 3.3e-05 24.0 0.0 4.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.6 EGG10202.1 - 5.2e-05 23.2 0.0 6.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_2 PF07646.15 EGG10202.1 - 0.00025 20.9 0.1 0.00034 20.5 0.1 1.3 1 1 0 1 1 1 1 Kelch motif Kelch_3 PF13415.6 EGG10202.1 - 0.066 13.5 0.3 0.11 12.8 0.0 1.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_4 PF13418.6 EGG10203.1 - 1.4e-06 28.2 0.5 2.1e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.6 EGG10203.1 - 8.4e-06 25.9 0.0 1.3e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_1 PF01344.25 EGG10203.1 - 2e-05 24.0 0.1 0.00035 20.1 0.1 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 EGG10203.1 - 0.0022 17.9 0.3 0.0086 16.0 0.1 1.9 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 EGG10203.1 - 0.0043 17.3 0.1 0.009 16.3 0.0 1.6 1 1 1 2 2 2 1 Kelch motif Kelch_5 PF13854.6 EGG10203.1 - 0.0077 16.2 0.8 0.03 14.3 0.1 2.0 2 0 0 2 2 2 1 Kelch motif RNA_pol_Rpb2_6 PF00562.28 EGG10204.1 - 2.5e-06 26.8 0.2 0.0033 16.6 0.1 2.1 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 NfrA_C PF13283.6 EGG10204.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term HTH_21 PF13276.6 EGG10205.1 - 0.00036 20.6 4.5 0.0019 18.3 2.2 2.8 3 1 0 3 3 3 1 HTH-like domain HTH_32 PF13565.6 EGG10205.1 - 0.0015 19.1 2.5 0.24 12.1 0.0 3.5 3 1 1 4 4 4 1 Homeodomain-like domain Clr5 PF14420.6 EGG10205.1 - 0.013 15.7 0.0 9.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Clr5 domain RecX PF02631.16 EGG10205.1 - 0.044 14.2 0.1 0.095 13.2 0.0 1.5 2 0 0 2 2 2 0 RecX family Mpv17_PMP22 PF04117.12 EGG10206.1 - 2.1e-07 31.0 1.1 4.3e-07 30.1 1.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family EB PF01683.18 EGG10207.1 - 0.36 11.2 29.3 0.58 10.5 1.1 4.0 2 1 1 3 3 3 0 EB module PsbT PF01405.17 EGG10207.1 - 7 6.6 5.5 16 5.4 5.5 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Pkinase PF00069.25 EGG10208.1 - 1.2e-59 201.9 0.0 3e-59 200.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG10208.1 - 5.1e-32 111.2 0.0 1.5e-31 109.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG10208.1 - 0.0026 17.1 0.1 0.0048 16.2 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGG10208.1 - 0.0039 16.2 0.2 0.0054 15.7 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGG10208.1 - 0.049 13.5 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 EGG10209.1 - 4.4e-09 36.8 19.2 0.83 10.6 0.0 10.4 10 1 1 11 11 11 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG10209.1 - 6.2e-07 29.6 0.2 7.5 6.9 0.0 5.9 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGG10209.1 - 0.15 12.1 0.6 8.2 6.5 0.1 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Pyr_redox_2 PF07992.14 EGG10210.1 - 1.6e-51 175.3 0.0 1.9e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG10210.1 - 1.2e-18 67.4 0.2 5.4e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG10210.1 - 1.3e-17 64.1 0.1 6.3e-15 55.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGG10210.1 - 2.5e-06 26.9 0.1 2.6e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EGG10210.1 - 2e-05 23.9 1.0 0.0044 16.2 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 EGG10210.1 - 0.00018 20.7 3.4 0.013 14.6 0.1 3.8 4 1 1 5 5 5 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGG10210.1 - 0.00091 19.4 0.1 0.026 14.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EGG10210.1 - 0.0011 18.4 0.2 0.022 14.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EGG10210.1 - 0.0029 17.2 1.1 0.6 9.6 0.4 2.8 1 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGG10210.1 - 0.011 15.0 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 EGG10210.1 - 0.012 16.0 0.0 0.8 10.2 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 EGG10210.1 - 0.013 14.3 0.3 0.038 12.7 0.3 1.8 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.14 EGG10210.1 - 0.022 13.6 0.1 0.092 11.6 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.20 EGG10210.1 - 0.065 13.3 0.1 7 6.7 0.0 2.8 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EGG10210.1 - 0.067 12.8 1.6 9.1 5.9 0.0 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA K_oxygenase PF13434.6 EGG10210.1 - 0.13 11.4 0.0 5.5 6.0 0.0 2.8 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Ribosomal_L5_C PF00673.21 EGG10212.1 - 7.9e-22 77.3 0.0 9e-22 77.1 0.0 1.0 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Miga PF10265.9 EGG10213.1 - 2.5 7.0 6.4 3.1 6.7 6.4 1.1 1 0 0 1 1 1 0 Mitoguardin Ndc1_Nup PF09531.10 EGG10213.1 - 7.8 5.1 6.1 8.3 5.0 6.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PTR2 PF00854.21 EGG10214.1 - 5.4e-86 288.9 5.4 7.3e-86 288.5 5.4 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EGG10214.1 - 6.4e-07 28.6 23.6 2e-06 27.0 21.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG10214.1 - 0.0069 15.3 0.9 0.0069 15.3 0.9 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter DUF3042 PF11240.8 EGG10214.1 - 0.033 14.2 0.6 6.3 6.9 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) XhlA PF10779.9 EGG10215.1 - 8.1 6.7 6.6 22 5.4 6.6 1.8 1 0 0 1 1 1 0 Haemolysin XhlA Arm PF00514.23 EGG10216.1 - 1.9e-92 300.8 13.1 1.7e-12 46.9 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EGG10216.1 - 3.3e-27 94.7 1.9 6.7e-27 93.8 1.9 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 EGG10216.1 - 1.1e-23 83.2 1.4 3.4e-08 33.8 0.0 6.0 4 1 2 6 6 6 5 HEAT-like repeat HEAT_2 PF13646.6 EGG10216.1 - 1.3e-19 70.4 0.0 5.8e-08 33.0 0.0 5.1 2 2 3 5 5 5 5 HEAT repeats Arm_3 PF16186.5 EGG10216.1 - 4.7e-19 67.7 2.0 1.3e-18 66.3 2.0 1.8 1 0 0 1 1 1 1 Atypical Arm repeat HEAT PF02985.22 EGG10216.1 - 1.3e-16 59.2 2.2 3.8e-06 26.7 0.0 6.8 8 0 0 8 8 8 3 HEAT repeat Arm_2 PF04826.13 EGG10216.1 - 2.2e-08 33.9 0.1 0.01 15.3 0.0 4.1 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 EGG10216.1 - 2.1e-07 29.9 0.0 1.5e-05 23.7 0.0 2.7 1 1 1 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.6 EGG10216.1 - 1.4e-06 28.4 1.5 0.079 13.2 0.0 4.7 3 2 1 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 EGG10216.1 - 5.7e-05 23.2 0.0 0.62 10.2 0.0 4.2 3 2 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.16 EGG10216.1 - 0.0018 18.8 2.8 0.67 10.8 0.1 5.1 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat V-ATPase_H_N PF03224.14 EGG10216.1 - 0.02 14.2 0.0 1.6 8.0 0.0 3.0 2 1 0 2 2 2 0 V-ATPase subunit H Mo25 PF08569.11 EGG10216.1 - 0.14 11.5 0.0 0.48 9.7 0.0 1.9 1 0 0 1 1 1 0 Mo25-like AAA_7 PF12775.7 EGG10217.1 - 0.012 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region HMG_box PF00505.19 EGG10218.1 - 0.047 14.1 0.3 0.12 12.8 0.3 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box Sec7 PF01369.20 EGG10223.1 - 1.5e-36 125.8 0.1 2.6e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EGG10223.1 - 9.8e-06 26.0 0.0 3e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EGG10223.1 - 0.022 15.1 0.2 0.022 15.1 0.2 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain Proton_antipo_M PF00361.20 EGG10224.1 - 3.1e-21 75.9 9.4 3.3e-21 75.8 9.4 1.0 1 0 0 1 1 1 1 Proton-conducting membrane transporter Dynactin_p62 PF05502.13 EGG10225.1 - 9.4e-73 245.6 12.7 1.2e-71 242.0 12.7 2.2 1 1 0 1 1 1 1 Dynactin p62 family Polysacc_deac_1 PF01522.21 EGG10226.1 - 1.3e-27 96.1 0.0 2.1e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGG10226.1 - 0.017 14.3 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 NUC153 PF08159.12 EGG10228.1 - 3.7e-14 52.2 11.9 4e-13 48.9 0.6 3.2 3 0 0 3 3 3 2 NUC153 domain Lsr2 PF11774.8 EGG10228.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.6 2 0 0 2 2 2 0 Lsr2 DUF4061 PF13270.6 EGG10228.1 - 1.3 9.4 5.4 0.68 10.3 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4061) Inhibitor_I71 PF12628.7 EGG10228.1 - 2.6 7.9 8.2 4.8 7.0 2.5 2.9 2 1 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor Alpha_kinase PF02816.18 EGG10229.1 - 1.6e-14 54.4 0.0 1.9e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Git3 PF11710.8 EGG10231.1 - 2.6e-15 56.7 9.6 4.2e-15 56.1 9.6 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 EGG10231.1 - 3e-06 26.6 6.8 4.1e-06 26.2 6.7 1.3 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor STE3 PF02076.15 EGG10231.1 - 9.3e-06 25.1 0.4 9.3e-06 25.1 0.4 2.0 1 1 0 1 1 1 1 Pheromone A receptor 7tm_1 PF00001.21 EGG10231.1 - 0.00039 19.8 5.2 0.00039 19.8 5.2 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 EGG10231.1 - 0.001 19.1 0.1 0.001 19.1 0.1 3.1 3 1 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Prp19 PF08606.11 EGG10232.1 - 7.5e-30 102.7 0.5 1.9e-29 101.4 0.5 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 EGG10232.1 - 5.4e-23 80.8 9.4 0.0038 18.0 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG10232.1 - 7.6e-17 61.4 0.9 2.2e-05 24.7 0.0 5.3 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG10232.1 - 0.0006 19.7 0.0 0.079 12.8 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A U-box PF04564.15 EGG10232.1 - 0.00073 19.7 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain BBS2_Mid PF14783.6 EGG10232.1 - 0.0034 17.4 0.1 0.02 14.9 0.0 2.3 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region zf-Nse PF11789.8 EGG10232.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EGG10232.1 - 0.16 12.1 0.0 0.8 9.9 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein Cep57_CLD_2 PF14197.6 EGG10232.1 - 0.51 10.5 2.7 1.6 8.9 2.2 2.0 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Yip1 PF04893.17 EGG10233.1 - 4.1e-11 42.9 13.0 1.3e-10 41.2 11.9 2.0 2 0 0 2 2 2 1 Yip1 domain SGTA_dimer PF16546.5 EGG10234.1 - 3.9e-05 23.3 0.0 6.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA VRR_NUC PF08774.11 EGG10234.1 - 0.0029 17.6 0.0 0.79 9.8 0.0 2.6 1 1 1 2 2 2 2 VRR-NUC domain STI1 PF17830.1 EGG10234.1 - 0.78 9.7 14.3 1.2 9.2 11.4 2.5 2 1 0 2 2 2 0 STI1 domain Retrotran_gag_2 PF14223.6 EGG10238.1 - 9.3e-06 25.4 0.3 1.5e-05 24.7 0.3 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGG10238.1 - 0.062 13.1 0.2 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type YL1 PF05764.13 EGG10241.1 - 0.016 15.3 9.9 0.019 15.1 9.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF4337 PF14235.6 EGG10241.1 - 0.022 14.9 4.3 0.026 14.6 4.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) TAF8_C PF10406.9 EGG10241.1 - 0.14 12.7 1.4 0.38 11.4 1.4 1.7 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term CDC45 PF02724.14 EGG10241.1 - 0.26 9.5 8.7 0.32 9.2 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 EGG10241.1 - 3.2 7.3 22.4 3.4 7.2 21.8 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein G-alpha PF00503.20 EGG10242.1 - 7.9e-26 91.1 0.4 2.4e-19 69.7 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.21 EGG10242.1 - 0.00037 20.0 0.0 0.00046 19.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family LAP1C PF05609.12 EGG10244.1 - 0.0036 16.5 16.8 0.005 16.0 16.8 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) SOBP PF15279.6 EGG10244.1 - 0.38 11.3 9.0 0.67 10.5 9.0 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein GREB1 PF15782.5 EGG10244.1 - 2.1 5.3 15.1 2.6 5.1 15.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PI3K_1B_p101 PF10486.9 EGG10244.1 - 3.1 5.4 21.8 4.3 5.0 21.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ndc1_Nup PF09531.10 EGG10244.1 - 3.5 6.2 8.9 4.5 5.9 8.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 EGG10244.1 - 7.3 4.9 21.2 9.6 4.6 21.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.9 EGG10244.1 - 10 4.6 22.4 15 4.0 22.4 1.2 1 0 0 1 1 1 0 Macoilin family DUF334 PF03904.13 EGG10246.1 - 0.4 10.2 1.5 0.5 9.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF334) DUF5382 PF17354.2 EGG10249.1 - 4 6.2 4.8 17 4.1 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5382) Baculo_PEP_C PF04513.12 EGG10251.1 - 0.00098 19.2 0.1 0.0016 18.5 0.1 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EGG10251.1 - 0.0021 18.1 0.4 0.0034 17.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 EGG10251.1 - 0.049 13.5 0.1 0.07 13.0 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Pox_Ag35 PF03286.14 EGG10252.1 - 0.04 13.7 7.2 0.047 13.5 7.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GCD14 PF08704.10 EGG10252.1 - 0.19 11.4 4.3 0.22 11.2 4.3 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Treacle PF03546.14 EGG10253.1 - 2.9 6.6 13.7 2 7.1 5.4 2.1 1 1 1 2 2 2 0 Treacher Collins syndrome protein Treacle DTHCT PF08070.11 EGG10253.1 - 5.9 7.7 9.0 1.3 9.8 5.0 2.1 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF2428 PF10350.9 EGG10255.1 - 5.5e-55 186.6 0.3 1.2e-54 185.4 0.3 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EGG10255.1 - 2e-08 33.8 8.6 0.026 14.8 0.0 6.5 6 1 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 EGG10255.1 - 0.002 18.4 6.6 0.0029 18.0 0.0 4.5 6 0 0 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 EGG10255.1 - 0.011 16.2 0.0 0.011 16.2 0.0 4.8 7 0 0 7 7 7 0 HEAT-like repeat SNF2_N PF00176.23 EGG10256.1 - 6.2e-56 189.6 0.3 1.6e-54 185.0 0.3 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG10256.1 - 2.8e-16 59.8 0.0 3.6e-15 56.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EGG10256.1 - 2.5e-06 26.9 0.1 3e-05 23.3 0.1 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EGG10256.1 - 4.4e-05 23.3 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.29 EGG10256.1 - 0.0002 21.2 17.2 0.0016 18.3 5.3 2.6 2 0 0 2 2 2 2 PHD-finger Ribul_P_3_epim PF00834.19 EGG10256.1 - 0.087 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family C1_2 PF03107.16 EGG10256.1 - 2 8.8 18.9 5.3 7.5 9.0 2.7 2 0 0 2 2 2 0 C1 domain zf-C4pol PF14260.6 EGG10256.1 - 6.9 7.2 14.4 1.1e+02 3.3 15.1 2.6 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta V-ATPase_C PF03223.15 EGG10257.1 - 2.7e-102 342.9 11.9 3e-102 342.8 11.9 1.0 1 0 0 1 1 1 1 V-ATPase subunit C PTPlike_phytase PF14566.6 EGG10257.1 - 0.032 14.3 3.0 0.052 13.7 0.3 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate APG6_N PF17675.1 EGG10257.1 - 3.5 8.2 12.3 0.3 11.6 0.2 3.1 3 0 0 3 3 3 0 Apg6 coiled-coil region Peptidase_M50 PF02163.22 EGG10258.1 - 8.7e-12 44.8 0.0 1.3e-07 31.1 0.0 2.6 2 1 0 2 2 2 2 Peptidase family M50 TPPII_N PF12583.8 EGG10259.1 - 1.5 9.4 4.2 1.8 9.1 4.2 1.1 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal SWIM PF04434.17 EGG10261.1 - 0.079 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 SWIM zinc finger EMP24_GP25L PF01105.24 EGG10262.1 - 6.6e-37 127.2 0.0 7.4e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SH3BGR PF04908.15 EGG10264.1 - 3.5e-08 33.5 0.3 9.2e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Metallophos PF00149.28 EGG10265.1 - 9.5e-36 124.2 0.1 1.6e-35 123.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGG10265.1 - 1.1e-17 64.1 0.1 2e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DnaJ PF00226.31 EGG10266.1 - 2.6e-11 43.5 0.3 7.2e-11 42.0 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.16 EGG10267.1 - 4.4e-23 81.8 27.4 1.4e-21 76.8 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2109 PF09882.9 EGG10267.1 - 5.2 7.1 6.7 2 8.5 0.8 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Glucan_synthase PF02364.15 EGG10267.1 - 6.1 4.9 5.2 0.56 8.3 0.5 1.5 2 0 0 2 2 2 0 1,3-beta-glucan synthase component SpoIIE PF07228.12 EGG10268.1 - 2.7e-11 43.8 0.0 4.7e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EGG10268.1 - 1.8e-10 40.9 0.0 3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EGG10268.1 - 2.2e-07 30.8 0.2 8.9e-05 22.2 0.0 2.5 2 1 0 2 2 2 2 Protein phosphatase 2C Tcf25 PF04910.14 EGG10271.1 - 1.1e-90 304.3 0.0 1.8e-90 303.5 0.0 1.4 1 1 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.6 EGG10271.1 - 0.078 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGG10271.1 - 0.12 12.7 1.8 5.1 7.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat GREB1 PF15782.5 EGG10271.1 - 0.95 6.5 16.2 1.4 6.0 16.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer E7 PF00527.18 EGG10271.1 - 2 8.6 4.1 13 6.1 4.1 2.4 1 0 0 1 1 1 0 E7 protein, Early protein DUF3509 PF12021.8 EGG10271.1 - 3 7.7 4.6 1.4 8.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) ATP-synt_G PF04718.15 EGG10276.1 - 3.8e-15 56.5 0.0 5.1e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit EFP PF01132.20 EGG10279.1 - 0.08 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain zf-C2H2_jaz PF12171.8 EGG10280.1 - 1.7e-05 25.0 4.0 2.6e-05 24.4 4.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EGG10280.1 - 0.024 15.1 2.8 0.049 14.1 2.8 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2802 PF10975.8 EGG10280.1 - 0.026 14.6 0.3 4.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) APOBEC3 PF18771.1 EGG10280.1 - 0.045 13.9 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 zf-C2H2_2 PF12756.7 EGG10280.1 - 0.053 13.9 0.1 0.085 13.2 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EGG10280.1 - 0.059 14.2 1.4 0.11 13.4 1.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HE PF16278.5 EGG10280.1 - 0.093 13.2 1.6 0.14 12.6 1.6 1.4 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger EMC3_TMCO1 PF01956.16 EGG10281.1 - 8e-54 181.9 0.3 1.6e-53 180.9 0.1 1.6 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like HTH_WhiA PF02650.14 EGG10283.1 - 0.09 13.1 0.6 22 5.5 0.2 3.2 1 1 1 2 2 2 0 WhiA C-terminal HTH domain Anoctamin PF04547.12 EGG10284.1 - 6.3e-93 312.1 18.6 8.1e-93 311.7 18.6 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Pex16 PF08610.10 EGG10285.1 - 2.1e-109 365.6 0.6 2.4e-109 365.4 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) PE PF00934.20 EGG10285.1 - 0.19 12.0 0.1 0.39 11.1 0.1 1.5 1 0 0 1 1 1 0 PE family Molybdopterin PF00384.22 EGG10286.1 - 2e-61 208.3 0.0 1e-60 206.0 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EGG10286.1 - 7.1e-18 64.4 0.1 1.7e-17 63.2 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 EGG10286.1 - 1.5e-17 62.8 0.2 1.5e-17 62.8 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 EGG10286.1 - 1.7e-14 54.2 0.0 4.9e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 EGG10286.1 - 1.5e-08 34.5 0.6 1.5e-08 34.5 0.6 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 EGG10286.1 - 0.14 11.9 0.0 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 EGG10286.1 - 0.44 10.4 3.1 8 6.5 0.4 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain F-box-like PF12937.7 EGG10287.1 - 2.2e-05 24.3 0.5 6.6e-05 22.7 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG10287.1 - 0.069 13.1 1.0 0.25 11.3 1.0 1.9 1 1 0 1 1 1 0 F-box domain YhfH PF14149.6 EGG10287.1 - 0.099 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 YhfH-like protein adh_short PF00106.25 EGG10288.1 - 3.5e-14 52.7 0.0 5.3e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG10288.1 - 5.2e-06 26.2 0.0 7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Kinesin PF00225.23 EGG10289.1 - 1.1e-89 300.7 0.9 2.9e-89 299.3 0.9 1.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGG10289.1 - 1.4e-14 54.3 0.0 3.4e-12 46.5 0.0 2.9 2 0 0 2 2 2 2 Microtubule binding Lipase_3 PF01764.25 EGG10290.1 - 1.1e-16 61.0 0.0 2.1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 EGG10290.1 - 0.13 12.1 0.1 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family API5 PF05918.11 EGG10291.1 - 0.49 9.1 9.3 0.79 8.5 9.3 1.5 1 1 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GHMP_kinases_N PF00288.26 EGG10293.1 - 2.1e-09 37.4 0.0 4.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGG10293.1 - 0.0048 17.2 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal EXS PF03124.14 EGG10296.1 - 1.4e-83 281.0 6.7 1.7e-83 280.7 6.7 1.1 1 0 0 1 1 1 1 EXS family Mac PF12464.8 EGG10297.1 - 4.2e-17 62.1 0.0 1e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 EGG10297.1 - 9.8e-11 40.9 10.5 5.8e-09 35.3 5.0 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) RRM_1 PF00076.22 EGG10297.1 - 0.00053 19.8 0.0 0.037 13.8 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hexapep_2 PF14602.6 EGG10297.1 - 0.00062 19.5 9.1 0.0018 18.0 4.1 2.5 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase XTBD PF11952.8 EGG10299.1 - 0.0031 17.3 0.2 0.017 14.9 0.0 2.1 2 0 0 2 2 2 1 XRN-Two Binding Domain, XTBD tRNA_anti-codon PF01336.25 EGG10299.1 - 0.076 13.0 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Proteasome PF00227.26 EGG10302.1 - 6.8e-29 100.7 0.0 8e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit TPR_14 PF13428.6 EGG10303.1 - 1.7e-08 34.5 2.7 0.0027 18.4 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG10303.1 - 1.9e-06 28.3 3.5 1.9 9.1 0.2 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGG10303.1 - 0.00017 21.8 6.1 0.033 14.5 1.0 4.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG10303.1 - 0.00018 21.4 3.9 1.1 9.5 0.0 5.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG10303.1 - 0.00051 20.6 0.5 0.0032 18.1 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG10303.1 - 0.00073 19.8 0.0 8.4 7.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG10303.1 - 0.018 15.2 2.4 4 7.7 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGG10303.1 - 0.059 13.0 0.9 1 9.0 0.1 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_8 PF13181.6 EGG10303.1 - 0.062 13.5 3.3 3.7 8.0 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG10303.1 - 0.38 11.5 3.4 17 6.3 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Acyl_transf_1 PF00698.21 EGG10304.1 - 4.4e-17 62.6 0.0 2e-05 24.3 0.1 3.0 3 0 0 3 3 3 3 Acyl transferase domain Pkinase PF00069.25 EGG10306.1 - 2.1e-23 83.0 3.5 1.4e-22 80.3 2.3 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG10306.1 - 1e-11 44.6 0.1 1.5e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EGG10306.1 - 0.00058 19.4 0.3 0.00097 18.7 0.3 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 EGG10306.1 - 0.0024 17.5 0.2 0.0059 16.2 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Amidase_6 PF12671.7 EGG10306.1 - 0.0094 16.1 1.1 0.022 14.8 1.1 1.7 1 0 0 1 1 1 1 Putative amidase domain Seadorna_VP7 PF07387.11 EGG10306.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 EGG10306.1 - 0.018 14.4 0.1 0.04 13.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 EGG10306.1 - 0.029 13.2 0.1 0.036 12.8 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGG10306.1 - 0.063 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HMG_box PF00505.19 EGG10307.1 - 0.012 16.0 0.1 0.058 13.8 0.1 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box HMG_box_2 PF09011.10 EGG10307.1 - 0.04 14.5 1.5 0.095 13.3 0.1 2.3 2 0 0 2 2 2 0 HMG-box domain DNA_pol_delta_4 PF04081.13 EGG10307.1 - 2.9 8.2 8.2 0.095 13.0 0.4 2.4 3 0 0 3 3 3 0 DNA polymerase delta, subunit 4 zf-CCHC_3 PF13917.6 EGG10308.1 - 0.00038 20.3 0.9 0.00068 19.6 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGG10308.1 - 0.096 12.8 2.4 0.15 12.2 2.4 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 EGG10308.1 - 0.15 11.9 0.1 0.35 10.7 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle CFEM PF05730.11 EGG10309.1 - 2.3e-08 34.0 7.8 2.3e-08 34.0 7.8 2.1 2 0 0 2 2 2 1 CFEM domain MHC2-interact PF09307.10 EGG10309.1 - 0.32 11.0 1.4 0.8 9.7 0.0 2.3 2 1 0 2 2 2 0 CLIP, MHC2 interacting UPF0242 PF06785.11 EGG10310.1 - 1.6 8.8 9.2 0.19 11.8 3.8 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MFS_1 PF07690.16 EGG10311.1 - 1e-34 120.0 36.5 5.2e-27 94.7 12.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG10311.1 - 1.9e-23 83.0 14.8 7.5e-23 81.1 14.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EGG10311.1 - 0.0012 18.3 16.8 0.022 14.1 0.9 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Choline_sulf_C PF12411.8 EGG10311.1 - 0.052 13.4 0.1 0.094 12.5 0.1 1.4 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal DUF485 PF04341.12 EGG10311.1 - 3.1 7.8 6.8 2 8.5 2.2 2.9 2 0 0 2 2 2 0 Protein of unknown function, DUF485 ATP_bind_1 PF03029.17 EGG10312.1 - 1e-78 264.5 0.4 2.2e-78 263.4 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EGG10312.1 - 3.6e-08 33.2 0.0 7.4e-07 28.9 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 EGG10312.1 - 7.5e-05 22.4 0.1 0.0013 18.3 0.1 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EGG10312.1 - 0.00015 21.8 0.0 0.0008 19.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 EGG10312.1 - 0.00024 20.8 0.0 0.018 14.7 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EGG10312.1 - 0.00029 20.6 0.0 0.00072 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG10312.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 EGG10312.1 - 0.0011 18.5 0.0 0.013 15.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EGG10312.1 - 0.0018 17.3 0.0 0.73 8.8 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EGG10312.1 - 0.0037 17.2 0.1 3.5 7.5 0.0 3.2 3 1 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EGG10312.1 - 0.0053 17.0 0.0 0.017 15.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 EGG10312.1 - 0.0057 16.4 0.1 0.23 11.2 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EGG10312.1 - 0.011 16.2 0.0 0.018 15.4 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 EGG10312.1 - 0.011 14.9 1.1 0.59 9.2 0.0 2.7 2 1 1 3 3 3 0 G-protein alpha subunit NACHT PF05729.12 EGG10312.1 - 0.012 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain CLP1_P PF16575.5 EGG10312.1 - 0.024 14.5 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRPRB PF09439.10 EGG10312.1 - 0.031 13.7 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 EGG10312.1 - 0.033 14.7 0.5 0.35 11.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain Arf PF00025.21 EGG10312.1 - 0.038 13.5 0.0 0.86 9.0 0.0 2.8 2 1 0 2 2 2 0 ADP-ribosylation factor family NB-ARC PF00931.22 EGG10312.1 - 0.038 13.2 0.0 0.092 11.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain PRK PF00485.18 EGG10312.1 - 0.044 13.5 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 EGG10312.1 - 0.052 13.1 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EGG10312.1 - 0.09 12.7 0.0 2.2 8.2 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 EGG10312.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PseudoU_synth_1 PF01416.20 EGG10313.1 - 1.3e-21 77.1 0.0 2.1e-19 70.0 0.0 3.4 2 1 0 2 2 2 1 tRNA pseudouridine synthase Ribosomal_L29 PF00831.23 EGG10313.1 - 0.069 13.1 2.3 0.2 11.7 0.6 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein EGF_Tenascin PF18720.1 EGG10315.1 - 0.024 14.7 2.6 0.067 13.3 2.6 1.7 1 0 0 1 1 1 0 Tenascin EGF domain HemN_C PF06969.16 EGG10315.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 HemN C-terminal domain AA_permease PF00324.21 EGG10318.1 - 1.7e-125 419.3 32.1 2.2e-125 419.0 32.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGG10318.1 - 2e-35 122.4 34.2 2.4e-35 122.2 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease HATPase_c PF02518.26 EGG10319.1 - 6.9e-28 97.4 0.0 1.6e-27 96.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGG10319.1 - 3.7e-25 88.3 0.0 1.2e-24 86.6 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain MHYT PF03707.16 EGG10319.1 - 1.3e-18 66.9 17.2 1.8e-10 40.8 0.5 4.4 4 0 0 4 4 4 2 Bacterial signalling protein N terminal repeat HisKA PF00512.25 EGG10319.1 - 2.7e-15 56.2 0.1 8.6e-15 54.5 0.1 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGG10319.1 - 0.15 11.9 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rpp20 PF12328.8 EGG10320.1 - 2.3e-06 27.6 1.3 1.7e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EGG10320.1 - 9.2e-06 25.4 0.2 2.1e-05 24.2 0.2 1.6 1 0 0 1 1 1 1 Alba Cellulase PF00150.18 EGG10321.1 - 1.4e-43 149.4 0.1 2e-43 148.9 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CTD_bind PF04818.13 EGG10322.1 - 0.00027 21.7 0.0 0.0011 19.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 EGG10322.1 - 0.0059 17.1 0.2 0.0059 17.1 0.2 2.8 2 1 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 Zn-C2H2_12 PF18112.1 EGG10322.1 - 0.019 15.4 0.2 0.053 14.0 0.2 1.8 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Npun_R1517 PF18068.1 EGG10324.1 - 0.29 11.5 0.1 0.29 11.5 0.1 2.3 3 0 0 3 3 3 0 Npun R1517 DUF4859 PF16151.5 EGG10324.1 - 0.4 10.6 3.3 0.86 9.5 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) KH_1 PF00013.29 EGG10328.1 - 1.1e-05 25.2 0.1 0.0083 15.9 0.0 2.3 2 0 0 2 2 2 2 KH domain NUDIX PF00293.28 EGG10329.1 - 5.4e-25 87.9 0.0 8.7e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain BTD PF09270.10 EGG10331.1 - 1.7e-27 96.6 0.0 3.2e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 EGG10331.1 - 3.9e-09 37.3 0.0 6.7e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 LAG1, DNA binding Mito_carr PF00153.27 EGG10332.1 - 1.1e-57 191.9 0.1 1.3e-16 60.3 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein Peptidase_M48_N PF16491.5 EGG10334.1 - 2.7e-44 151.2 8.6 9.3e-44 149.5 8.6 1.9 1 1 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EGG10334.1 - 1.4e-36 126.1 0.7 1.3e-35 123.0 0.0 2.4 1 1 1 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 EGG10334.1 - 0.06 12.5 0.2 0.19 10.9 0.2 1.7 1 1 0 1 1 1 0 BlaR1 peptidase M56 YukC PF10140.9 EGG10336.1 - 0.056 12.3 0.8 3.7 6.3 0.1 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC HMG_box PF00505.19 EGG10337.1 - 4.8e-05 23.7 0.0 9.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box CxC5 PF18718.1 EGG10338.1 - 1.1e-17 64.1 6.0 1.8e-17 63.5 6.0 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases PID PF00640.23 EGG10338.1 - 0.19 11.8 1.0 0.29 11.2 1.0 1.3 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) RNA_pol_Rpb1_5 PF04998.17 EGG10339.1 - 6.6e-47 160.2 0.1 8.2e-47 159.9 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 EGG10339.1 - 5.4e-05 23.1 0.0 0.00051 20.0 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 GPAT_N PF14829.6 EGG10339.1 - 0.11 12.5 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal zf-RRN7 PF11781.8 EGG10341.1 - 0.032 13.9 0.1 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DAO PF01266.24 EGG10344.1 - 1.9e-36 126.4 0.0 2.5e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG10344.1 - 0.0016 17.8 0.0 0.079 12.2 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG10344.1 - 0.0022 18.2 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain KR PF08659.10 EGG10344.1 - 0.0086 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Amino_oxidase PF01593.24 EGG10344.1 - 0.0089 15.4 0.0 0.052 12.8 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase adh_short PF00106.25 EGG10344.1 - 0.21 11.0 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GIDA PF01134.22 EGG10344.1 - 0.25 10.4 0.0 1.2 8.1 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_transf_90 PF05686.12 EGG10345.1 - 2.1e-10 40.1 3.2 1.7e-07 30.5 0.2 3.2 3 1 0 3 3 3 2 Glycosyl transferase family 90 GWT1 PF06423.12 EGG10345.1 - 0.18 11.9 0.9 0.37 10.9 0.9 1.6 1 1 0 1 1 1 0 GWT1 Atypical_Card PF18461.1 EGG10348.1 - 0.089 13.0 0.1 0.2 11.9 0.1 1.6 1 1 0 1 1 1 0 Atypical caspase recruitment domain DUF3493 PF11998.8 EGG10348.1 - 0.091 12.9 0.0 0.091 12.9 0.0 1.7 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 CLIP1_ZNF PF16641.5 EGG10352.1 - 0.099 12.6 1.3 0.13 12.1 0.4 1.7 2 0 0 2 2 2 0 CLIP1 zinc knuckle zf-CCHC_6 PF15288.6 EGG10352.1 - 0.61 10.0 1.9 1.9 8.4 1.4 2.1 1 1 1 2 2 2 0 Zinc knuckle HAUS5 PF14817.6 EGG10353.1 - 0.00064 18.6 2.9 0.001 18.0 2.9 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 zf-CCHC PF00098.23 EGG10353.1 - 0.024 14.7 0.3 0.046 13.8 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle NPV_P10 PF05531.12 EGG10353.1 - 0.024 15.1 1.2 3.4 8.2 0.2 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 EGG10353.1 - 0.034 14.5 5.7 2.1 8.8 0.0 3.0 3 1 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TolA_bind_tri PF16331.5 EGG10353.1 - 0.062 13.4 5.9 1.7 8.8 0.1 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF1993 PF09351.10 EGG10353.1 - 0.084 13.0 2.5 0.073 13.2 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) SlyX PF04102.12 EGG10353.1 - 0.12 13.0 5.5 3 8.5 1.4 2.9 2 0 0 2 2 2 0 SlyX DNA_topoisoIV PF00521.20 EGG10353.1 - 0.14 11.0 5.3 0.17 10.7 1.8 2.1 2 0 0 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A FlaC_arch PF05377.11 EGG10353.1 - 0.16 12.4 2.1 19 5.7 0.5 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FlxA PF14282.6 EGG10353.1 - 0.36 10.8 7.2 0.74 9.8 1.4 2.5 1 1 0 2 2 2 0 FlxA-like protein HalX PF08663.10 EGG10353.1 - 0.4 11.0 3.3 4 7.8 0.3 2.8 2 0 0 2 2 2 0 HalX domain Fez1 PF06818.15 EGG10353.1 - 0.79 10.1 7.5 1.3 9.4 7.5 1.3 1 0 0 1 1 1 0 Fez1 Fzo_mitofusin PF04799.13 EGG10353.1 - 0.85 9.2 2.5 7.4 6.1 0.3 2.4 2 0 0 2 2 2 0 fzo-like conserved region COG2 PF06148.11 EGG10353.1 - 0.89 9.6 4.9 0.8 9.8 0.2 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_GP20 PF06810.11 EGG10353.1 - 1.2 9.0 8.4 1.1 9.1 5.0 2.3 2 1 0 2 2 1 0 Phage minor structural protein GP20 ZapB PF06005.12 EGG10353.1 - 1.5 9.3 11.2 0.86 10.1 2.8 2.4 1 1 1 2 2 2 0 Cell division protein ZapB Spectrin PF00435.21 EGG10353.1 - 1.9 9.0 7.3 2 9.0 2.3 2.7 1 1 1 2 2 2 0 Spectrin repeat LPP PF04728.13 EGG10353.1 - 2.4 8.6 7.6 11 6.5 0.1 3.0 3 0 0 3 3 2 0 Lipoprotein leucine-zipper YabA PF06156.13 EGG10353.1 - 2.5 8.8 7.8 2.8 8.6 0.4 2.7 1 1 1 2 2 2 0 Initiation control protein YabA Swi5 PF07061.11 EGG10353.1 - 3.2 7.9 6.5 1.5 8.9 0.9 2.9 2 1 0 2 2 2 0 Swi5 Alanine_zipper PF11839.8 EGG10353.1 - 3.3 8.2 6.2 32 5.0 0.1 3.4 3 0 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein Lectin_N PF03954.14 EGG10353.1 - 3.6 7.3 5.7 7.5 6.3 0.1 2.9 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF4164 PF13747.6 EGG10353.1 - 3.8 7.9 9.9 3.2 8.1 1.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) DUF5082 PF16888.5 EGG10353.1 - 3.9 7.8 5.8 15 5.9 0.2 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) BLOC1_2 PF10046.9 EGG10353.1 - 6.1 7.2 11.7 0.2 12.0 0.4 3.1 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MbeD_MobD PF04899.12 EGG10353.1 - 7.3 6.8 6.9 2.2 8.5 0.6 3.0 4 0 0 4 4 3 0 MbeD/MobD like Phasin PF05597.11 EGG10353.1 - 7.8 6.5 7.2 16 5.6 2.3 2.7 2 1 1 3 3 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Sad1_UNC PF07738.13 EGG10355.1 - 7.9e-30 103.6 0.0 1.5e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF3494 PF11999.8 EGG10355.1 - 0.036 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) EF-hand_7 PF13499.6 EGG10357.1 - 1.2e-16 60.9 0.2 9.3e-09 35.6 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGG10357.1 - 9.1e-16 56.2 1.7 7.2e-06 25.2 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGG10357.1 - 2.6e-14 51.9 1.9 7e-06 25.6 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EGG10357.1 - 1.2e-08 34.7 1.1 3.9e-05 23.4 0.2 3.6 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EGG10357.1 - 9.5e-08 32.3 0.0 0.0012 19.1 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGG10357.1 - 0.00012 21.4 0.4 0.77 9.4 0.0 3.4 3 0 0 3 3 3 2 EF hand EFhand_Ca_insen PF08726.10 EGG10357.1 - 0.018 15.1 0.0 0.064 13.4 0.0 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand UPF0154 PF03672.13 EGG10357.1 - 0.033 14.2 0.0 5.8 7.0 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 EGG10357.1 - 0.16 12.8 0.0 0.72 10.8 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain Aa_trans PF01490.18 EGG10358.1 - 7.3e-51 173.1 23.4 1.8e-50 171.9 23.4 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGG10358.1 - 0.041 12.9 20.0 0.013 14.6 10.8 2.2 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family DUF5392 PF17370.2 EGG10359.1 - 0.041 14.0 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5392) DUF974 PF06159.13 EGG10361.1 - 6.1e-65 219.5 0.2 8.3e-65 219.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) TFIIS_M PF07500.14 EGG10362.1 - 2.2e-28 99.0 0.6 3.8e-28 98.2 0.4 1.5 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EGG10362.1 - 2.4e-12 46.5 2.8 4.1e-12 45.8 2.8 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EGG10362.1 - 1.7e-10 40.8 0.6 2.8e-10 40.0 0.6 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Solute_trans_a PF03619.16 EGG10363.1 - 1.4e-77 260.8 18.8 1.8e-77 260.4 18.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha TPR_8 PF13181.6 EGG10365.1 - 2.2e-05 24.3 5.1 3 8.3 0.2 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG10365.1 - 0.00071 20.0 2.8 4 8.0 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG10365.1 - 0.0016 18.7 1.2 0.53 10.8 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG10365.1 - 0.0023 18.6 6.8 31 5.7 0.2 6.0 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGG10365.1 - 0.0049 16.6 0.6 1.6 8.7 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGG10365.1 - 0.023 14.3 0.9 5.5 6.8 0.5 3.7 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.17 EGG10365.1 - 0.082 13.1 7.5 2.1 8.6 0.2 5.4 8 0 0 8 8 8 0 Tetratricopeptide repeat HHH_9 PF17674.1 EGG10365.1 - 0.37 11.7 1.4 1.3 10.0 0.1 2.7 3 0 0 3 3 3 0 HHH domain TPR_9 PF13371.6 EGG10365.1 - 0.83 9.8 3.3 10 6.3 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CBS PF00571.28 EGG10367.1 - 0.017 15.5 0.0 0.059 13.8 0.0 1.8 2 0 0 2 2 2 0 CBS domain Pheromone PF08015.11 EGG10367.1 - 0.026 15.5 3.3 1.8 9.7 0.0 2.4 1 1 1 2 2 2 0 Fungal mating-type pheromone RRM_1 PF00076.22 EGG10368.1 - 2.6e-26 91.2 3.9 1.3e-08 34.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG10368.1 - 3.7e-08 33.1 0.0 0.17 11.7 0.0 4.2 4 0 0 4 4 4 2 Occluded RNA-recognition motif DUF4523 PF15023.6 EGG10368.1 - 9.3e-05 22.3 0.0 1.1 9.1 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 EGG10368.1 - 0.0028 17.7 0.5 0.94 9.6 0.5 3.1 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.6 EGG10368.1 - 0.007 16.3 0.0 25 5.0 0.0 3.8 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.6 EGG10368.1 - 0.063 13.1 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) RNA_bind PF08675.11 EGG10368.1 - 0.55 10.3 1.7 3.3 7.8 0.0 2.8 3 0 0 3 3 3 0 RNA binding domain DUF3432 PF11914.8 EGG10368.1 - 3.7 7.9 10.8 19 5.5 9.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3432) RRM_1 PF00076.22 EGG10369.1 - 1.2e-06 28.2 0.8 2.1e-06 27.5 0.8 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RasGEF PF00617.19 EGG10369.1 - 0.00031 21.0 0.0 0.00054 20.2 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RRM_occluded PF16842.5 EGG10369.1 - 0.024 14.5 0.1 0.074 12.9 0.0 1.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_3 PF08777.11 EGG10369.1 - 0.15 12.1 0.4 0.23 11.5 0.4 1.2 1 0 0 1 1 1 0 RNA binding motif DUF4523 PF15023.6 EGG10369.1 - 0.19 11.5 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) G10 PF01125.17 EGG10371.1 - 5.1e-65 217.7 2.8 5.7e-65 217.5 2.8 1.0 1 0 0 1 1 1 1 G10 protein adh_short PF00106.25 EGG10373.1 - 1.1e-19 70.7 0.0 3.1e-19 69.2 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG10373.1 - 3e-13 49.9 0.0 3.5e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG10373.1 - 0.011 15.6 0.1 0.022 14.7 0.1 1.5 1 1 0 1 1 1 0 KR domain LRIF1 PF15741.5 EGG10375.1 - 0.065 11.8 5.6 0.078 11.5 5.6 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 O-antigen_lig PF13425.6 EGG10375.1 - 0.27 10.0 0.7 0.33 9.7 0.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein U1snRNP70_N PF12220.8 EGG10375.1 - 8.8 7.1 9.0 4.8 7.9 4.2 2.1 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DSBA PF01323.20 EGG10376.1 - 9.1e-23 81.0 0.0 1.1e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Membrane_bind PF14564.6 EGG10377.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Membrane binding PLDc_2 PF13091.6 EGG10378.1 - 2.7e-13 50.0 0.0 1.5e-06 28.1 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGG10378.1 - 0.00041 20.4 5.2 0.19 12.0 0.3 3.4 2 1 0 2 2 2 2 Phospholipase D Active site motif tRNA-synt_2 PF00152.20 EGG10379.1 - 1.1e-85 287.5 0.0 1.5e-85 287.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGG10379.1 - 6e-12 45.4 0.0 1.4e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EGG10379.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF4407 PF14362.6 EGG10379.1 - 0.16 11.3 1.1 0.23 10.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MWFE PF15879.5 EGG10381.1 - 2.6e-23 81.9 0.5 3.2e-23 81.7 0.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit adh_short PF00106.25 EGG10382.1 - 1.4e-18 67.1 0.1 7.1e-12 45.2 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG10382.1 - 2.8e-11 43.4 0.0 5e-08 32.8 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG10382.1 - 0.074 13.0 0.7 0.17 11.8 0.1 1.8 1 1 1 2 2 2 0 KR domain Ndc1_Nup PF09531.10 EGG10384.1 - 0.37 9.4 3.3 0.42 9.2 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 EGG10384.1 - 0.52 9.4 8.2 0.63 9.2 8.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Menin PF05053.13 EGG10384.1 - 3.6 5.8 5.7 4.2 5.6 5.7 1.1 1 0 0 1 1 1 0 Menin TMEM95 PF15203.6 EGG10385.1 - 0.055 13.1 0.7 0.43 10.2 0.1 1.9 1 1 1 2 2 2 0 TMEM95 family FixS PF03597.15 EGG10385.1 - 0.095 12.4 0.5 0.16 11.7 0.5 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Oxidored_FMN PF00724.20 EGG10388.1 - 6.5e-35 121.0 0.0 7.8e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Chitin_synth_1 PF01644.17 EGG10391.1 - 8.3e-78 260.0 0.0 1.4e-77 259.3 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 EGG10391.1 - 6.8e-28 97.6 2.0 4.3e-20 71.8 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 EGG10391.1 - 1.6e-24 85.7 0.0 4.9e-24 84.1 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.6 EGG10391.1 - 0.0064 16.4 0.0 0.013 15.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGG10391.1 - 0.051 13.5 19.5 0.011 15.6 12.7 2.9 2 1 0 2 2 2 0 Glycosyl transferase family group 2 DUF4079 PF13301.6 EGG10391.1 - 2 8.6 5.9 9.2 6.4 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Cep3 PF16846.5 EGG10392.1 - 0.1 11.1 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B XTBD PF11952.8 EGG10393.1 - 0.013 15.2 0.1 0.067 13.0 0.0 2.1 2 0 0 2 2 2 0 XRN-Two Binding Domain, XTBD p450 PF00067.22 EGG10395.1 - 1.2e-63 215.5 0.0 1.5e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YbjQ_1 PF01906.17 EGG10396.1 - 0.06 14.0 0.1 0.22 12.2 0.1 2.0 1 0 0 1 1 1 0 Putative heavy-metal-binding MMS22L_C PF14911.6 EGG10398.1 - 0.064 12.3 0.0 0.071 12.2 0.0 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Glyco_hydro_25 PF01183.20 EGG10399.1 - 0.043 14.0 0.1 0.046 13.9 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 25 DUF3484 PF11983.8 EGG10400.1 - 7.6 7.7 9.4 54 5.0 9.4 2.2 1 1 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch EF-hand_1 PF00036.32 EGG10401.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 EF hand Pkinase PF00069.25 EGG10403.1 - 1.8e-71 240.6 0.0 2.4e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG10403.1 - 1.4e-31 109.8 0.0 1.9e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGG10403.1 - 4.8e-14 52.8 2.4 1.1e-13 51.7 2.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGG10403.1 - 5e-05 22.8 0.0 0.0002 20.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGG10403.1 - 0.00052 19.1 0.0 0.00075 18.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGG10403.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG10403.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGG10403.1 - 0.084 12.5 0.0 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HSP70 PF00012.20 EGG10404.1 - 1.9e-157 525.1 0.7 2.3e-157 524.8 0.1 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EGG10404.1 - 5.6e-12 45.1 0.0 1.6e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.8 EGG10404.1 - 0.0018 17.4 0.0 0.26 10.3 0.0 2.4 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; zf-RRN7 PF11781.8 EGG10406.1 - 0.026 14.2 0.6 0.068 12.9 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 His_biosynth PF00977.21 EGG10407.1 - 8.2e-43 146.5 0.1 2e-41 142.0 0.1 2.6 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EGG10407.1 - 6.3e-21 75.0 0.0 1e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EGG10407.1 - 4.2e-09 36.3 0.0 7.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 EGG10407.1 - 1.1e-06 28.6 0.0 1.4e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family TMP-TENI PF02581.17 EGG10407.1 - 0.022 14.1 0.0 1.7 7.9 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase Dus PF01207.17 EGG10407.1 - 0.14 11.2 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.13 EGG10407.1 - 0.15 11.8 0.2 0.46 10.2 0.2 1.8 1 1 0 1 1 1 0 Peptidase C26 ATP-synt_C PF00137.21 EGG10408.1 - 1.4e-28 99.0 30.4 3e-21 75.5 13.1 2.4 2 1 0 2 2 2 2 ATP synthase subunit C Hydrolase_4 PF12146.8 EGG10409.1 - 1e-51 175.5 0.0 1.2e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG10409.1 - 2e-13 51.5 0.0 2.4e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG10409.1 - 1.5e-11 44.5 0.0 2.2e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG10409.1 - 3.5e-06 26.6 0.4 0.0043 16.6 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 EGG10409.1 - 0.00046 19.8 0.1 0.76 9.3 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EGG10409.1 - 0.0056 16.5 0.1 0.74 9.6 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 EGG10409.1 - 0.0083 15.1 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.13 EGG10409.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.15 EGG10409.1 - 0.019 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase FSH1 PF03959.13 EGG10409.1 - 0.033 13.8 0.1 0.11 12.1 0.1 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 EGG10409.1 - 0.088 12.6 0.0 6.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family AXE1 PF05448.12 EGG10409.1 - 0.11 11.2 1.3 0.75 8.4 0.0 2.3 2 1 0 3 3 3 0 Acetyl xylan esterase (AXE1) Esterase PF00756.20 EGG10409.1 - 0.13 11.9 0.0 5.8 6.5 0.0 2.3 2 1 0 2 2 2 0 Putative esterase DUF1749 PF08538.10 EGG10409.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF202 PF02656.15 EGG10410.1 - 1.7e-18 66.8 0.2 5.7e-18 65.1 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF202) CrgA PF06781.12 EGG10410.1 - 0.0038 17.3 0.0 0.028 14.5 0.0 2.0 2 0 0 2 2 2 1 Cell division protein CrgA Spc7 PF08317.11 EGG10411.1 - 0.016 14.1 3.9 0.028 13.3 3.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Rab5-bind PF09311.11 EGG10411.1 - 0.027 13.9 2.8 0.048 13.0 2.8 1.3 1 0 0 1 1 1 0 Rabaptin-like protein FlxA PF14282.6 EGG10411.1 - 0.052 13.5 3.9 0.11 12.5 3.9 1.5 1 1 0 1 1 1 0 FlxA-like protein TPR_MLP1_2 PF07926.12 EGG10411.1 - 0.059 13.4 2.9 0.12 12.4 2.9 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1796 PF08795.10 EGG10411.1 - 0.063 13.2 0.9 0.2 11.6 0.1 2.1 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) OmpH PF03938.14 EGG10411.1 - 0.083 13.2 2.2 0.13 12.6 2.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 EGG10411.1 - 0.98 9.9 3.8 13 6.3 3.6 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SET PF00856.28 EGG10415.1 - 1.1e-06 29.2 0.0 2.9e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EGG10415.1 - 0.0048 17.6 0.3 0.014 16.1 0.0 1.9 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Cellulase PF00150.18 EGG10416.1 - 6.1e-07 29.1 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GRA6 PF05084.13 EGG10416.1 - 0.0016 18.4 0.4 0.004 17.1 0.4 1.6 1 0 0 1 1 1 1 Granule antigen protein (GRA6) Pilin_N PF07790.11 EGG10416.1 - 0.016 16.2 0.6 0.035 15.0 0.6 1.5 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal ETRAMP PF09716.10 EGG10416.1 - 0.17 11.9 0.2 0.31 11.1 0.2 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) FAS_I_H PF18314.1 EGG10417.1 - 4.1e-08 33.1 0.0 7.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Abhydrolase_2 PF02230.16 EGG10418.1 - 1e-26 94.1 0.0 3.1e-26 92.5 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGG10418.1 - 0.00011 22.9 0.2 0.00031 21.4 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGG10418.1 - 0.028 14.1 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF4634 PF15465.6 EGG10419.1 - 0.16 12.3 0.2 0.36 11.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) Zn_clus PF00172.18 EGG10420.1 - 0.0034 17.5 11.3 0.0071 16.4 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EGG10420.1 - 0.0041 17.1 0.0 0.008 16.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EGG10420.1 - 0.093 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 EGG10420.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 PAS domain DUF3729 PF12526.8 EGG10421.1 - 0.41 12.2 7.4 0.25 12.9 3.8 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3729) Sugar_tr PF00083.24 EGG10422.1 - 2.3e-33 115.7 30.4 9.6e-19 67.6 9.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGG10422.1 - 1.5e-17 63.6 68.9 1.8e-16 60.0 39.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ac76 PF05814.11 EGG10422.1 - 0.032 14.2 1.0 6.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) DUF3226 PF11536.8 EGG10422.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Mannosyl_trans2 PF04188.13 EGG10423.1 - 3.5e-12 46.4 1.5 3.8e-12 46.3 1.5 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Ras PF00071.22 EGG10427.1 - 3.3e-39 134.1 0.0 3.8e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG10427.1 - 2.4e-10 40.7 0.0 3e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG10427.1 - 0.005 16.3 0.0 0.0059 16.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family pXO2-34 PF17362.2 EGG10427.1 - 0.035 14.0 0.0 0.068 13.1 0.0 1.5 1 1 0 1 1 1 0 Family of unknown function MMR_HSR1 PF01926.23 EGG10427.1 - 0.075 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF1729 PF08354.10 EGG10429.1 - 1.1e-152 508.1 0.0 1.7e-152 507.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) SAT PF16073.5 EGG10429.1 - 7.5e-30 104.4 0.0 1.5e-29 103.4 0.0 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_meander PF17951.1 EGG10429.1 - 3.3e-06 27.0 0.9 7.1e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 EGG10429.1 - 5e-05 23.3 9.4 0.00041 20.4 9.4 2.3 1 1 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MBOAT_2 PF13813.6 EGG10431.1 - 9.2e-11 41.9 2.6 9.2e-11 41.9 2.6 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Mito_carr PF00153.27 EGG10432.1 - 1.5e-56 188.3 5.0 3.8e-24 84.4 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein AAA_2 PF07724.14 EGG10433.1 - 3.1e-52 177.1 0.3 2.2e-46 158.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGG10433.1 - 4.2e-28 97.3 6.9 5.9e-28 96.8 0.2 3.0 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EGG10433.1 - 1e-21 76.8 3.3 2.8e-21 75.3 2.1 2.6 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EGG10433.1 - 4.6e-21 75.6 2.7 1.7e-10 41.4 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGG10433.1 - 5.9e-18 65.2 0.1 4.2e-12 46.2 0.0 3.4 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGG10433.1 - 3.3e-12 46.9 1.9 0.00041 20.6 0.0 4.4 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EGG10433.1 - 2.2e-11 43.8 0.3 3.3e-07 30.2 0.0 3.4 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 EGG10433.1 - 3.8e-11 43.7 1.9 0.0002 21.8 0.1 4.4 2 2 2 4 4 4 2 AAA ATPase domain AAA_14 PF13173.6 EGG10433.1 - 1.8e-09 37.7 2.5 2.6e-05 24.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 EGG10433.1 - 1.1e-07 31.5 0.0 0.004 16.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 EGG10433.1 - 8.7e-07 29.5 0.4 0.028 15.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain TniB PF05621.11 EGG10433.1 - 2.3e-06 27.2 0.0 0.013 15.0 0.0 3.8 2 1 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 EGG10433.1 - 4.9e-06 26.4 0.1 0.085 12.6 0.1 2.9 2 1 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 EGG10433.1 - 7.4e-06 26.0 8.8 0.11 12.4 0.1 4.3 3 1 1 4 4 4 2 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EGG10433.1 - 1.9e-05 25.0 0.0 0.32 11.4 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 EGG10433.1 - 6.8e-05 22.3 0.9 0.83 9.0 0.0 3.5 3 1 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 EGG10433.1 - 8e-05 22.4 0.0 0.13 12.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGG10433.1 - 0.00011 22.1 0.0 0.58 9.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 EGG10433.1 - 0.00012 22.3 0.0 0.5 10.6 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase DNA_pol3_delta2 PF13177.6 EGG10433.1 - 0.00013 21.8 0.0 0.0029 17.4 0.0 2.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit RsgA_GTPase PF03193.16 EGG10433.1 - 0.00017 21.6 0.1 0.74 9.7 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 EGG10433.1 - 0.00026 20.9 0.0 0.085 12.6 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EGG10433.1 - 0.00035 21.1 2.0 0.13 12.8 0.0 3.7 3 0 0 3 3 3 1 ABC transporter RuvB_N PF05496.12 EGG10433.1 - 0.00057 19.7 1.5 1.8 8.3 0.6 3.6 3 1 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGG10433.1 - 0.00096 19.4 0.0 2.7 8.2 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 EGG10433.1 - 0.0011 18.2 0.9 2.3 7.3 0.0 3.5 3 1 0 3 3 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 EGG10433.1 - 0.0012 18.8 0.1 0.31 11.0 0.0 3.2 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 EGG10433.1 - 0.0014 18.7 0.0 1.6 8.7 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE HAUS2 PF15003.6 EGG10433.1 - 0.0019 18.0 1.5 0.0045 16.7 1.5 1.6 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 PduV-EutP PF10662.9 EGG10433.1 - 0.0023 17.7 0.0 1.4 8.7 0.0 3.2 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EGG10433.1 - 0.0023 17.6 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 EGG10433.1 - 0.0047 16.6 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EGG10433.1 - 0.011 16.1 1.5 1.5 9.2 0.1 3.5 2 2 0 2 2 2 0 AAA domain ResIII PF04851.15 EGG10433.1 - 0.012 15.6 5.3 0.28 11.2 0.0 3.8 3 2 2 5 5 4 0 Type III restriction enzyme, res subunit PhoH PF02562.16 EGG10433.1 - 0.05 13.1 0.0 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 EGG10433.1 - 0.055 13.6 0.0 13 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EGG10433.1 - 0.058 12.4 0.0 2.5 7.0 0.0 2.6 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region Seryl_tRNA_N PF02403.22 EGG10433.1 - 0.13 12.5 9.9 0.59 10.4 8.8 2.8 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain AAA_23 PF13476.6 EGG10433.1 - 0.19 12.2 29.0 0.07 13.6 0.8 4.4 3 2 0 3 3 2 0 AAA domain AAA_3 PF07726.11 EGG10433.1 - 0.2 11.5 1.9 1.8 8.4 0.1 3.1 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EGG10433.1 - 0.48 10.3 3.4 24 4.8 0.1 3.3 3 1 0 3 3 3 0 NTPase AAA_21 PF13304.6 EGG10433.1 - 0.57 9.9 4.0 7 6.3 0.0 3.4 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Cob_adeno_trans PF01923.18 EGG10433.1 - 1.3 9.2 3.8 2 8.5 1.3 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase ABC_tran_CTD PF16326.5 EGG10433.1 - 1.4 9.2 13.2 0.58 10.4 7.8 2.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain UPF0184 PF03670.13 EGG10433.1 - 1.8 9.0 4.1 1.6 9.2 1.3 2.3 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0184) Atg14 PF10186.9 EGG10433.1 - 2.6 7.0 7.5 5.7 5.9 7.5 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CHD5 PF04420.14 EGG10433.1 - 3 7.7 4.5 6.2 6.7 4.5 1.5 1 0 0 1 1 1 0 CHD5-like protein PRKG1_interact PF15898.5 EGG10433.1 - 4.1 8.4 17.1 0.23 12.4 6.5 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain FlxA PF14282.6 EGG10433.1 - 6 6.9 11.7 3.2 7.8 4.8 2.4 1 1 1 2 2 2 0 FlxA-like protein ADH_zinc_N PF00107.26 EGG10434.1 - 2.6e-26 92.1 0.0 4.7e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG10434.1 - 6.9e-07 29.1 0.0 4.9e-05 23.2 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGG10434.1 - 4.7e-06 27.7 0.0 8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGG10434.1 - 0.0064 16.4 0.0 0.02 14.8 0.0 1.8 1 1 1 2 2 2 1 N-terminal domain of oxidoreductase RskA PF10099.9 EGG10437.1 - 0.0025 18.2 0.2 0.0027 18.0 0.2 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TMEM52 PF14979.6 EGG10437.1 - 0.1 12.5 1.2 0.13 12.2 1.2 1.4 1 1 0 1 1 1 0 Transmembrane 52 Amastin PF07344.11 EGG10438.1 - 0.031 14.1 0.3 0.031 14.1 0.3 2.1 2 1 0 2 2 2 0 Amastin surface glycoprotein DUF417 PF04224.12 EGG10438.1 - 0.063 12.8 0.1 0.096 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF417 AC_N PF16214.5 EGG10438.1 - 0.37 9.9 1.2 0.67 9.0 0.2 1.7 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region MFS_1 PF07690.16 EGG10439.1 - 0.0015 17.6 9.5 0.0015 17.6 9.5 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3902 PF13042.6 EGG10439.1 - 0.033 13.8 6.9 0.017 14.7 3.9 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3902) Cadherin PF00028.17 EGG10439.1 - 0.1 13.0 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 Cadherin domain KdgT PF03812.13 EGG10439.1 - 0.13 11.5 0.2 0.13 11.5 0.2 2.6 1 1 2 3 3 3 0 2-keto-3-deoxygluconate permease MFS_1 PF07690.16 EGG10440.1 - 3.9e-15 55.7 24.0 1.1e-14 54.2 24.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Ldh_1_N PF00056.23 EGG10441.1 - 1.4e-09 38.2 0.0 8.3e-08 32.4 0.0 2.0 1 1 1 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EGG10442.1 - 4.8e-38 130.7 0.1 3.1e-37 128.1 0.1 1.9 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGG10442.1 - 8.1e-24 84.3 0.1 1e-22 80.7 0.0 2.1 1 1 1 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain ThrE PF06738.12 EGG10445.1 - 1.2e-47 162.3 24.0 6.8e-47 159.9 7.2 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EGG10445.1 - 6.3e-15 55.4 10.4 6.3e-15 55.4 10.4 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF4574 PF15141.6 EGG10445.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF4229 PF14012.6 EGG10445.1 - 4.4 7.5 13.1 2.2 8.5 0.5 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) tRNA_U5-meth_tr PF05958.11 EGG10447.1 - 2.9e-23 82.5 0.4 2.3e-21 76.2 0.1 3.2 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 EGG10447.1 - 2.5e-08 33.6 0.0 4.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 EGG10447.1 - 6.4e-07 29.3 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG10447.1 - 4.2e-06 27.4 0.0 3.3e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG10447.1 - 2.1e-05 25.1 0.0 0.00023 21.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 EGG10447.1 - 0.0015 18.4 0.1 0.0089 15.8 0.0 2.2 2 1 1 3 3 3 1 Met-10+ like-protein PrmA PF06325.13 EGG10447.1 - 0.0015 18.0 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EGG10447.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Cons_hypoth95 PF03602.15 EGG10447.1 - 0.05 13.2 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 EGG10447.1 - 0.086 12.2 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF2828 PF11443.8 EGG10447.1 - 0.12 10.5 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) HCV_NS5a_1b PF08301.13 EGG10448.1 - 0.13 12.8 0.2 0.34 11.5 0.2 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b RdRP PF05183.12 EGG10451.1 - 8.5e-69 232.7 0.0 4.9e-61 207.1 0.0 3.9 1 1 1 2 2 2 2 RNA dependent RNA polymerase 60KD_IMP PF02096.20 EGG10451.1 - 0.035 14.0 0.6 0.071 13.0 0.6 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein ATP-cone PF03477.16 EGG10451.1 - 0.69 10.5 3.4 0.76 10.4 0.0 2.9 4 0 0 4 4 4 0 ATP cone domain C9orf72-like PF15019.6 EGG10452.1 - 0.058 13.0 0.2 0.085 12.4 0.2 1.2 1 0 0 1 1 1 0 C9orf72-like protein family zinc_ribbon_16 PF17034.5 EGG10453.1 - 2.4e-09 37.5 19.3 4.5e-06 26.9 10.7 2.0 1 1 1 2 2 2 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EGG10453.1 - 9.5e-06 25.2 18.2 9.5e-06 25.2 18.2 2.1 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type Zn-ribbon_8 PF09723.10 EGG10453.1 - 2.5 8.3 12.1 2.4 8.3 1.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Palm_thioest PF02089.15 EGG10454.1 - 1.7e-79 267.1 0.0 2e-79 266.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EGG10454.1 - 0.0039 16.9 0.0 0.01 15.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 EGG10454.1 - 0.04 13.6 0.0 0.073 12.7 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Baculo_PEP_C PF04513.12 EGG10455.1 - 0.015 15.3 4.3 0.33 11.0 0.2 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PCP PF02429.15 EGG10455.1 - 0.024 15.0 0.1 0.024 15.0 0.1 2.9 3 1 1 4 4 4 0 Peridinin-chlorophyll A binding protein EURL PF06937.11 EGG10455.1 - 0.081 12.3 0.2 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 EURL protein Ribosomal_S2 PF00318.20 EGG10456.1 - 8e-26 90.6 0.2 3.5e-15 55.8 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EGG10456.1 - 4.7e-06 27.9 14.0 9.4e-06 26.9 14.0 1.6 1 1 0 1 1 1 1 40S ribosomal protein SA C-terminus BTG PF07742.12 EGG10458.1 - 6.9e-15 54.9 0.0 1.2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 BTG family Baculo_PEP_C PF04513.12 EGG10459.1 - 2.6 8.1 12.3 0.044 13.8 3.7 2.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.25 EGG10460.1 - 1.6e-21 76.8 0.0 2e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG10460.1 - 1.7e-08 34.1 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGG10460.1 - 0.0034 16.8 0.0 0.0046 16.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGG10460.1 - 0.0064 15.8 0.0 0.019 14.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGG10460.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family RVT_3 PF13456.6 EGG10461.1 - 1.2e-06 28.3 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like ABC_transp_aux PF09822.9 EGG10461.1 - 0.059 12.8 0.2 0.51 9.8 0.1 2.0 1 1 1 2 2 2 0 ABC-type uncharacterized transport system RT_RNaseH PF17917.1 EGG10461.1 - 0.087 13.1 0.1 0.6 10.4 0.1 2.4 1 1 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Rrp15p PF07890.12 EGG10463.1 - 6.2e-29 101.0 2.4 6.2e-29 101.0 2.4 3.7 1 1 1 2 2 2 1 Rrp15p Amino_oxidase PF01593.24 EGG10464.1 - 8.2e-48 163.8 0.0 2.8e-47 162.0 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGG10464.1 - 3.1e-14 52.9 0.0 6.6e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG10464.1 - 4.5e-08 32.7 0.0 6.5e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGG10464.1 - 7.1e-08 32.4 1.0 4.8e-06 26.4 0.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGG10464.1 - 1.2e-07 31.1 0.6 1.9e-07 30.6 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGG10464.1 - 3e-06 26.9 0.0 4.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGG10464.1 - 6e-06 26.7 0.1 1.4e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGG10464.1 - 1.1e-05 24.8 0.1 1.9e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EGG10464.1 - 2.1e-05 23.8 0.0 3.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGG10464.1 - 2.7e-05 23.1 0.5 4e-05 22.5 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EGG10464.1 - 0.00036 19.9 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EGG10464.1 - 0.00074 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EGG10464.1 - 0.0017 17.7 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGG10464.1 - 0.0022 17.3 0.5 0.0038 16.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 EGG10464.1 - 0.078 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EGG10464.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EGG10464.1 - 0.089 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 EGG10464.1 - 0.19 12.0 0.1 0.33 11.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain RSN1_7TM PF02714.15 EGG10465.1 - 6.1e-12 45.4 8.9 6.1e-12 45.4 8.9 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate DUF3169 PF11368.8 EGG10465.1 - 0.029 13.9 3.1 1 8.8 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Intg_mem_TP0381 PF09529.10 EGG10465.1 - 0.58 9.6 10.6 0.16 11.5 3.1 2.7 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) SUR7 PF06687.12 EGG10466.1 - 1.3e-06 28.2 1.3 1.9e-06 27.7 1.3 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF872 PF05915.12 EGG10466.1 - 0.4 10.9 1.6 1.4 9.1 1.0 2.2 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Alpha_kinase PF02816.18 EGG10467.1 - 2.5e-16 60.3 0.2 3.7e-16 59.8 0.2 1.2 1 0 0 1 1 1 1 Alpha-kinase family Glucan_synthase PF02364.15 EGG10469.1 - 6e-71 239.7 4.7 3.4e-60 204.2 1.8 3.7 1 1 1 2 2 2 2 1,3-beta-glucan synthase component Syntaxin-18_N PF10496.9 EGG10469.1 - 0.051 13.8 0.1 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DNA_pol_B_exo1 PF03104.19 EGG10470.1 - 0.049 12.8 0.1 0.069 12.3 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain DUF4733 PF15878.5 EGG10472.1 - 0.093 13.2 0.1 0.36 11.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4733) Aquarius_N PF16399.5 EGG10472.1 - 0.099 10.7 0.2 0.13 10.3 0.2 1.1 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus TPR_6 PF13174.6 EGG10474.1 - 0.0018 18.8 1.5 1.7 9.4 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG10474.1 - 0.0058 16.7 0.9 2.1 8.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG10474.1 - 0.047 14.0 0.2 2 8.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG10474.1 - 0.074 13.1 0.1 26 5.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGG10474.1 - 0.075 13.5 0.0 1.6 9.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG10474.1 - 0.22 11.7 0.5 19 5.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TRP PF06011.12 EGG10475.1 - 4.1e-52 177.4 22.2 2.6e-51 174.7 22.1 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGG10475.1 - 2.3e-27 96.1 0.4 3.5e-27 95.5 0.4 1.3 1 0 0 1 1 1 1 ML-like domain ERO1 PF04137.15 EGG10476.1 - 1.5e-127 425.7 0.4 1.9e-127 425.3 0.4 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Phage_TAC_10 PF10963.8 EGG10478.1 - 0.11 12.7 0.0 5.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone DUF1360 PF07098.11 EGG10480.1 - 0.091 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Dioxygenase_C PF00775.21 EGG10481.1 - 3.2e-07 30.0 0.1 1.7e-06 27.6 0.1 2.0 1 1 0 1 1 1 1 Dioxygenase Dioxygenase_C PF00775.21 EGG10482.1 - 4.6e-07 29.5 0.1 4.7e-06 26.2 0.1 2.2 1 1 0 1 1 1 1 Dioxygenase PA_decarbox PF05870.11 EGG10482.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) CRISPR_Cas9_WED PF18061.1 EGG10483.1 - 0.031 14.3 0.7 0.1 12.7 0.3 2.0 1 1 0 1 1 1 0 CRISPR-Cas9 WED domain Acetyltransf_10 PF13673.7 EGG10484.1 - 1e-06 28.7 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG10484.1 - 1.4e-06 28.5 0.0 2.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG10484.1 - 1.5e-06 28.6 0.0 2.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG10484.1 - 5.7e-05 23.0 0.0 9.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EGG10484.1 - 0.042 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Adeno_E3_CR2 PF02439.15 EGG10485.1 - 0.006 16.3 0.4 0.012 15.4 0.4 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Orf78 PF06024.12 EGG10485.1 - 0.037 14.3 0.6 0.34 11.2 0.1 2.4 2 0 0 2 2 2 0 Orf78 (ac78) RIFIN PF02009.16 EGG10485.1 - 0.093 12.6 4.5 0.18 11.7 4.5 1.5 1 1 0 1 1 1 0 Rifin AsmA PF05170.14 EGG10486.1 - 0.07 11.9 0.1 0.088 11.6 0.1 1.1 1 0 0 1 1 1 0 AsmA family 2-Hacid_dh PF00389.30 EGG10486.1 - 0.16 11.7 4.4 0.071 12.8 0.7 2.1 1 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Popeye PF04831.13 EGG10486.1 - 0.18 11.9 0.6 0.35 11.0 0.6 1.4 1 0 0 1 1 1 0 Popeye protein conserved region Med11 PF10280.9 EGG10489.1 - 9e-15 55.3 1.3 1.2e-14 54.9 0.1 1.9 2 0 0 2 2 2 1 Mediator complex protein Cwf_Cwc_15 PF04889.12 EGG10489.1 - 3.3 7.4 8.7 0.63 9.7 4.9 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 EGG10491.1 - 9e-36 123.6 0.0 1e-35 123.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG10491.1 - 3.4e-18 65.9 0.0 3.8e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG10491.1 - 0.0015 17.9 0.0 0.018 14.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EGG10491.1 - 0.009 15.6 0.0 1.9 8.0 0.0 2.1 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGG10491.1 - 0.026 13.9 0.0 0.051 12.9 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_carr PF00153.27 EGG10494.1 - 3e-66 219.4 0.6 2.2e-24 85.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Spermine_synth PF01564.17 EGG10495.1 - 8e-10 38.4 0.5 1.4e-09 37.6 0.5 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain MBOAT_2 PF13813.6 EGG10497.1 - 1.2e-11 44.7 2.2 2e-11 44.0 0.7 2.1 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family CorA PF01544.18 EGG10500.1 - 1.6e-32 113.0 12.8 1.3e-19 70.6 1.3 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein UBA PF00627.31 EGG10502.1 - 4.1e-28 96.9 3.7 1.4e-14 53.7 1.4 2.8 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 EGG10502.1 - 2.7e-20 71.9 12.4 4.8e-20 71.1 12.4 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 EGG10502.1 - 8.4e-17 60.7 1.2 1.3e-16 60.1 1.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGG10502.1 - 4.3e-05 23.2 2.6 7.1e-05 22.6 2.6 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 EGG10502.1 - 0.00012 21.8 0.3 0.37 10.6 0.0 3.2 3 0 0 3 3 3 2 Fungal ubiquitin-associated domain Ubiquitin_5 PF18037.1 EGG10502.1 - 0.014 15.7 0.5 0.024 15.0 0.5 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain DUF1421 PF07223.11 EGG10502.1 - 0.19 11.6 0.0 18 5.3 0.0 2.5 2 0 0 2 2 2 0 UBA-like domain (DUF1421) STI1 PF17830.1 EGG10502.1 - 0.28 11.1 6.2 3 7.9 4.6 3.1 2 1 0 2 2 2 0 STI1 domain PRCC PF10253.9 EGG10502.1 - 3.7 8.3 14.4 16 6.2 0.4 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting HC2 PF07382.11 EGG10503.1 - 2.6e-06 27.7 0.0 3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Peptidase_S64 PF08192.11 EGG10505.1 - 1.8 6.9 22.5 2.2 6.6 22.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 zf-C2H2 PF00096.26 EGG10506.1 - 3.3e-13 49.3 14.0 2.9e-05 24.3 0.6 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGG10506.1 - 2.2e-09 37.1 5.0 0.00054 19.9 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGG10506.1 - 2.7e-09 37.0 13.0 0.00021 21.6 0.6 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG10506.1 - 5.6e-07 29.9 20.4 0.00075 20.1 0.5 4.3 5 0 0 5 5 3 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EGG10506.1 - 0.00039 21.1 9.2 0.096 13.4 0.1 2.9 2 1 0 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 EGG10506.1 - 0.0073 16.7 2.6 2.7 8.5 0.2 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type C1_4 PF07975.12 EGG10506.1 - 0.034 14.4 2.1 5.1 7.4 0.4 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 EGG10506.1 - 0.04 14.1 5.3 3.4 7.9 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-CCHC_2 PF13696.6 EGG10506.1 - 0.054 13.3 3.0 2.6 7.9 0.6 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_8 PF15909.5 EGG10506.1 - 0.13 12.5 3.4 0.37 11.1 1.3 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon Rpr2 PF04032.16 EGG10506.1 - 0.13 12.5 1.9 3.6 8.0 0.1 2.5 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_jaz PF12171.8 EGG10506.1 - 0.21 11.9 0.2 0.21 11.9 0.2 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Cript PF10235.9 EGG10506.1 - 0.31 11.6 7.0 0.74 10.4 0.7 2.7 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT C5HCH PF17982.1 EGG10506.1 - 0.48 10.6 6.4 1.5 9.0 0.9 3.2 2 1 1 3 3 3 0 NSD Cys-His rich domain Elf1 PF05129.13 EGG10506.1 - 0.52 10.4 4.0 5.1 7.2 0.7 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like HNH PF01844.23 EGG10506.1 - 6.6 7.0 8.9 14 5.9 0.1 3.5 3 0 0 3 3 3 0 HNH endonuclease CpXC PF14353.6 EGG10506.1 - 7.1 6.7 8.5 3.5 7.7 1.4 2.7 1 1 1 2 2 2 0 CpXC protein ANAPC4_WD40 PF12894.7 EGG10507.1 - 1.3e-09 38.3 0.1 0.00087 19.5 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG10507.1 - 1.4e-09 38.4 6.8 8.6e-06 26.4 0.2 5.9 7 0 0 7 7 7 1 WD domain, G-beta repeat PQQ_3 PF13570.6 EGG10507.1 - 0.00028 21.3 0.1 0.0013 19.2 0.0 2.1 2 0 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.16 EGG10507.1 - 0.0035 15.9 0.0 1.2 7.6 0.0 2.8 2 1 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 EGG10507.1 - 0.0068 15.8 0.0 0.39 10.0 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 EGG10507.1 - 0.031 14.2 0.0 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DNase_II PF03265.15 EGG10508.1 - 0.065 12.5 5.5 0.07 12.4 1.6 2.3 2 0 0 2 2 2 0 Deoxyribonuclease II CxC1 PF18802.1 EGG10510.1 - 0.032 14.4 0.5 0.099 12.8 0.2 2.0 2 0 0 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases CPSase_L_D2 PF02786.17 EGG10511.1 - 3.3e-73 245.7 0.0 5.1e-73 245.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGG10511.1 - 1.3e-38 131.9 0.0 2.9e-38 130.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGG10511.1 - 5.3e-33 113.4 0.0 9.9e-33 112.5 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGG10511.1 - 2.5e-15 56.1 6.6 4e-15 55.4 4.6 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGG10511.1 - 2.5e-11 43.5 0.0 5.8e-11 42.3 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGG10511.1 - 2e-08 34.0 0.0 4.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGG10511.1 - 0.00079 19.5 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EGG10511.1 - 0.0034 18.1 0.4 0.027 15.2 0.1 2.5 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.19 EGG10511.1 - 0.0035 17.2 0.2 0.0088 15.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_D23 PF16576.5 EGG10511.1 - 0.0068 15.7 0.8 0.067 12.4 0.1 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 EGG10511.1 - 0.0075 16.1 3.8 0.075 12.9 0.3 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like ATPgrasp_ST PF14397.6 EGG10511.1 - 0.021 14.1 0.2 0.92 8.7 0.0 2.6 3 0 0 3 3 3 0 Sugar-transfer associated ATP-grasp NQRA PF05896.11 EGG10511.1 - 0.024 14.1 0.6 0.047 13.1 0.6 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Transp_cyt_pur PF02133.15 EGG10512.1 - 2.7e-100 336.2 25.5 3e-100 336.1 25.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin F-box-like PF12937.7 EGG10513.1 - 0.00032 20.5 3.1 0.00032 20.5 3.1 3.1 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 EGG10513.1 - 0.00066 19.5 1.7 0.75 9.8 0.3 3.4 3 0 0 3 3 3 2 F-box domain LRR_4 PF12799.7 EGG10513.1 - 0.26 11.8 10.9 0.19 12.2 1.7 4.4 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) TBPIP PF07106.13 EGG10514.1 - 2.3e-16 59.4 0.5 2.3e-16 59.4 0.5 2.4 3 0 0 3 3 3 1 TBPIP/Hop2 winged helix domain Med11 PF10280.9 EGG10514.1 - 0.0015 19.0 3.8 0.0017 18.8 2.5 1.7 1 1 0 1 1 1 1 Mediator complex protein DUF1822 PF08852.11 EGG10514.1 - 0.075 12.0 10.8 0.091 11.8 10.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1822) Salt_tol_Pase PF09506.10 EGG10514.1 - 0.63 8.7 6.6 0.61 8.8 3.5 2.0 1 1 1 2 2 2 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) HALZ PF02183.18 EGG10514.1 - 0.64 10.3 11.1 1.3 9.3 1.0 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper CENP-H PF05837.12 EGG10514.1 - 0.87 10.0 14.6 0.49 10.8 7.0 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) BRX_N PF13713.6 EGG10514.1 - 0.9 9.4 7.6 2.6 7.9 0.3 2.9 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain DHR10 PF18595.1 EGG10514.1 - 1.7 8.7 13.8 0.47 10.5 7.6 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain GTP-bdg_M PF16360.5 EGG10514.1 - 1.8 9.2 7.2 0.37 11.4 1.9 2.3 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region MIEAP PF16026.5 EGG10514.1 - 4.2 7.5 7.6 2.7 8.2 5.5 1.7 1 1 0 1 1 1 0 Mitochondria-eating protein LMBR1 PF04791.16 EGG10514.1 - 7.5 5.3 9.8 9.3 5.0 9.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SNF2_N PF00176.23 EGG10515.1 - 2.8e-55 187.4 0.1 4.4e-55 186.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG10515.1 - 4.5e-17 62.4 0.0 1.3e-16 60.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG10515.1 - 6.4e-07 29.5 0.0 3.6e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGG10515.1 - 0.00019 20.7 0.0 0.00045 19.5 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF4710 PF15828.5 EGG10515.1 - 8 6.7 11.1 4.7 7.4 3.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4710) Utp13 PF08625.11 EGG10516.1 - 0.037 13.9 0.1 10 6.0 0.0 2.5 2 1 0 2 2 2 0 Utp13 specific WD40 associated domain DUF1962 PF09227.10 EGG10517.1 - 0.015 15.6 2.5 0.015 15.6 2.5 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF1962) Alpha-amylase PF00128.24 EGG10518.1 - 1.2e-27 97.4 1.1 4.2e-27 95.6 1.1 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 EGG10518.1 - 6.5e-07 29.4 1.7 1.1e-06 28.7 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) Alpha-amylase_C PF02806.18 EGG10518.1 - 4.9e-06 26.9 0.7 0.00013 22.3 0.0 2.6 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Glyco_hydro_70 PF02324.16 EGG10518.1 - 0.0065 14.7 0.0 0.6 8.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 70 DUF3043 PF11241.8 EGG10519.1 - 9.9 6.2 7.1 0.41 10.7 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) MFS_1 PF07690.16 EGG10520.1 - 8.3e-30 103.9 38.6 2.4e-29 102.4 38.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily FHIPEP PF00771.20 EGG10520.1 - 0.18 10.3 1.1 0.23 9.9 1.1 1.1 1 0 0 1 1 1 0 FHIPEP family BCDHK_Adom3 PF10436.9 EGG10521.1 - 5.2e-12 45.9 0.1 8.6e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase YmdB PF13277.6 EGG10521.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 YmdB-like protein CENP-B_dimeris PF09026.10 EGG10523.1 - 0.47 10.9 10.9 1.9 8.9 2.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NST1 PF13945.6 EGG10523.1 - 0.52 10.4 21.2 0.18 11.9 14.8 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator UPF0688 PF15772.5 EGG10523.1 - 3.4 7.8 18.4 0.19 12.0 10.2 2.0 2 0 0 2 2 2 0 UPF0688 family PLA2_B PF01735.18 EGG10524.1 - 2.2e-81 273.7 0.8 2.8e-81 273.4 0.8 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 EGG10524.1 - 0.063 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Patatin-like phospholipase Pantoate_transf PF02548.15 EGG10525.1 - 9.3e-71 238.2 0.0 1.4e-69 234.4 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase tRNA-synt_1 PF00133.22 EGG10526.1 - 2.4e-219 729.6 0.0 3.3e-219 729.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGG10526.1 - 2.8e-25 89.1 0.0 5.7e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGG10526.1 - 6.9e-13 48.1 1.0 0.00013 20.9 0.1 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGG10526.1 - 0.0025 17.2 0.0 0.041 13.2 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain DUF3658 PF12395.8 EGG10526.1 - 0.0031 17.4 0.6 4.5 7.2 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function SWIB PF02201.18 EGG10526.1 - 0.051 13.5 0.3 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 SWIB/MDM2 domain BRE1 PF08647.11 EGG10527.1 - 2.3e-19 69.3 9.8 2.3e-19 69.3 9.8 7.2 6 1 1 7 7 7 2 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.25 EGG10527.1 - 8.8e-07 28.7 12.0 1.5e-06 27.9 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG10527.1 - 2.3e-06 27.3 10.2 4e-06 26.6 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG10527.1 - 6.9e-06 25.9 12.1 1.2e-05 25.2 12.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGG10527.1 - 1.7e-05 24.6 11.4 3e-05 23.8 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG10527.1 - 0.00016 21.4 8.8 0.0003 20.6 8.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGG10527.1 - 0.0016 18.7 11.0 0.0036 17.6 11.0 1.6 1 0 0 1 1 1 1 Ring finger domain PKcGMP_CC PF16808.5 EGG10527.1 - 0.0035 17.2 1.0 0.0035 17.2 1.0 5.3 6 0 0 6 6 5 2 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-RING_UBOX PF13445.6 EGG10527.1 - 0.0041 17.1 8.0 0.0087 16.1 8.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGG10527.1 - 0.037 14.3 7.0 0.075 13.3 7.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EGG10527.1 - 0.1 12.5 3.7 0.22 11.4 3.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF3824 PF12868.7 EGG10527.1 - 0.31 11.7 3.4 1.3 9.7 3.4 2.1 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) CVNH PF08881.10 EGG10527.1 - 0.52 11.0 0.1 0.52 11.0 0.1 2.9 4 0 0 4 4 4 0 CVNH domain zf-C3HC4_4 PF15227.6 EGG10527.1 - 1.5 9.1 7.7 2.8 8.2 7.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING MAD PF05557.13 EGG10527.1 - 5.3 5.3 75.7 0.033 12.6 35.0 3.4 2 2 1 3 3 3 0 Mitotic checkpoint protein ANTH PF07651.16 EGG10529.1 - 1.1e-48 165.6 0.0 1.6e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.11 EGG10529.1 - 0.00011 22.6 20.8 0.00011 22.6 20.8 3.5 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) ENTH PF01417.20 EGG10529.1 - 0.0034 17.4 0.1 0.024 14.7 0.0 2.1 2 0 0 2 2 2 1 ENTH domain Baculo_PEP_C PF04513.12 EGG10530.1 - 0.0067 16.5 1.1 0.012 15.6 1.1 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ATE_C PF04377.15 EGG10531.1 - 2.8e-46 157.5 0.2 5.7e-46 156.5 0.2 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EGG10531.1 - 3.3e-24 85.1 1.6 5.8e-24 84.3 1.6 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus PEPcase PF00311.17 EGG10531.1 - 0.011 13.9 0.0 0.015 13.5 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase RabGAP-TBC PF00566.18 EGG10532.1 - 0.00014 21.6 0.0 0.0005 19.8 0.0 2.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SecE PF00584.20 EGG10534.1 - 2.8e-16 59.2 0.0 3.6e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex HBB PF06777.11 EGG10534.1 - 0.14 11.8 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Helical and beta-bridge domain DUF1654 PF07867.11 EGG10540.1 - 0.016 15.0 1.8 0.033 13.9 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) 2OG-FeII_Oxy PF03171.20 EGG10541.1 - 2.4e-19 69.7 0.0 3.8e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Polyketide_cyc PF03364.20 EGG10542.1 - 1.8e-18 67.0 0.1 2.4e-18 66.6 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport KH_1 PF00013.29 EGG10543.1 - 1.2e-62 207.6 59.1 2.1e-09 37.1 0.6 13.9 13 1 0 13 13 13 12 KH domain SLS PF14611.6 EGG10543.1 - 6.9e-06 26.0 15.3 0.0052 16.7 1.5 5.9 5 2 2 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EGG10543.1 - 2.6e-05 23.9 36.8 0.063 13.1 0.2 8.3 7 2 1 8 8 8 5 KH domain KH_4 PF13083.6 EGG10543.1 - 0.64 9.9 15.8 2 8.4 0.3 6.6 6 0 0 6 6 6 0 KH domain Secretin_N PF03958.17 EGG10543.1 - 3.1 8.3 10.2 11 6.5 0.0 5.2 7 0 0 7 7 7 0 Bacterial type II/III secretion system short domain CDV3 PF15359.6 EGG10543.1 - 5.5 7.5 9.6 1.1 9.8 0.6 2.8 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 tRNA-synt_1c PF00749.21 EGG10545.1 - 1.2e-104 349.6 0.0 1.9e-104 348.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGG10545.1 - 2.3e-34 118.8 0.0 4.7e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 EGG10545.1 - 8.2e-34 116.9 1.5 8.9e-34 116.8 0.3 1.7 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 EGG10545.1 - 1.2e-05 26.1 1.4 2.1e-05 25.3 0.3 2.0 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Peptidase_M16 PF00675.20 EGG10546.1 - 0.065 13.2 0.2 0.21 11.6 0.2 1.8 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) adh_short PF00106.25 EGG10548.1 - 6.5e-19 68.2 0.1 3.4e-12 46.2 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG10548.1 - 1.6e-11 44.2 0.0 2.8e-08 33.6 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG10548.1 - 0.036 14.0 0.7 0.082 12.8 0.1 1.8 1 1 1 2 2 2 0 KR domain WD40 PF00400.32 EGG10549.1 - 1.7e-49 164.7 28.2 1.8e-06 28.6 0.1 11.4 11 0 0 11 11 11 8 WD domain, G-beta repeat Utp13 PF08625.11 EGG10549.1 - 7.5e-37 126.4 0.2 1.4e-36 125.5 0.2 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EGG10549.1 - 5e-14 52.4 7.0 0.00062 20.0 0.1 7.7 5 3 4 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG10549.1 - 0.00023 19.9 6.1 0.83 8.2 0.0 5.5 3 1 4 7 7 7 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGG10549.1 - 0.0012 17.8 6.8 0.89 8.4 0.1 4.5 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 EGG10549.1 - 0.027 14.4 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat VID27 PF08553.10 EGG10549.1 - 0.029 13.4 0.5 0.42 9.6 0.0 2.4 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Glyco_transf_20 PF00982.21 EGG10551.1 - 1e-143 479.5 0.0 1.2e-143 479.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGG10551.1 - 1.2e-67 227.5 0.0 1.7e-67 227.0 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.20 EGG10551.1 - 0.013 15.0 0.0 2.7 7.5 0.0 2.8 2 1 0 2 2 2 0 Glycosyl transferases group 1 DUF202 PF02656.15 EGG10552.1 - 2.1e-18 66.5 5.4 3e-18 66.0 3.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) zf-MYND PF01753.18 EGG10555.1 - 2.3e-08 34.0 14.9 4e-08 33.2 14.9 1.4 1 0 0 1 1 1 1 MYND finger TPR_12 PF13424.6 EGG10555.1 - 2.8e-08 33.9 0.4 7.8e-05 22.9 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG10555.1 - 0.00012 21.9 0.0 0.1 12.8 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG10555.1 - 0.00029 20.8 0.3 0.021 15.0 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG10555.1 - 0.00062 19.5 0.1 1.1 9.2 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGG10555.1 - 0.0045 16.8 0.0 0.041 13.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG10555.1 - 0.033 14.6 0.0 6.9 7.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 EGG10555.1 - 0.038 13.6 0.8 0.18 11.4 0.1 1.9 2 0 0 2 2 2 0 Foie gras liver health family 1 TPR_14 PF13428.6 EGG10555.1 - 0.038 14.8 0.0 0.18 12.7 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.9 EGG10555.1 - 0.039 13.6 0.4 0.27 10.9 0.3 2.1 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_19 PF14559.6 EGG10555.1 - 0.045 14.3 0.0 0.082 13.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EGG10555.1 - 0.062 12.7 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 MalT-like TPR region TPR_11 PF13414.6 EGG10555.1 - 0.092 12.4 0.0 1.1 9.0 0.0 2.5 1 1 1 2 2 2 0 TPR repeat DUF4801 PF16059.5 EGG10555.1 - 0.17 11.9 8.2 0.47 10.4 8.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4801) zf-C6H2 PF15801.5 EGG10555.1 - 2 8.8 14.7 3.5 8.0 14.7 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Arf PF00025.21 EGG10557.1 - 7.1e-76 253.5 0.0 8e-76 253.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG10557.1 - 1.6e-15 57.3 0.0 2.1e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG10557.1 - 5e-13 49.0 0.0 5.9e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGG10557.1 - 3.5e-12 46.1 0.0 4.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGG10557.1 - 5.1e-12 45.6 1.1 1.8e-07 30.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGG10557.1 - 7.9e-10 38.5 0.0 9.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG10557.1 - 6.2e-05 23.1 0.0 9.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGG10557.1 - 0.0021 17.4 0.1 0.0036 16.7 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase MobB PF03205.14 EGG10557.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SpoOE-like PF09388.10 EGG10557.1 - 0.34 10.9 1.6 0.65 9.9 1.6 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein HAMP PF00672.25 EGG10558.1 - 5.1e-49 164.5 35.3 7e-10 39.1 1.1 11.1 8 4 3 11 11 11 8 HAMP domain HATPase_c PF02518.26 EGG10558.1 - 1.3e-28 99.7 1.4 2.9e-28 98.6 1.4 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGG10558.1 - 3.7e-21 75.4 0.1 1.2e-20 73.8 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGG10558.1 - 3.1e-16 59.1 2.4 1.1e-15 57.4 0.4 3.2 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain DUF1843 PF08898.10 EGG10558.1 - 6e-07 29.9 12.9 0.14 12.7 0.2 7.0 7 0 0 7 7 7 2 Domain of unknown function (DUF1843) Syntaxin_2 PF14523.6 EGG10558.1 - 0.0011 19.3 9.6 11 6.5 0.0 7.6 4 2 3 8 8 8 1 Syntaxin-like protein Mer2 PF09074.10 EGG10558.1 - 0.0016 18.3 6.9 0.026 14.3 0.2 3.5 3 1 0 3 3 3 2 Mer2 DUF948 PF06103.11 EGG10558.1 - 0.0033 17.7 41.1 0.13 12.6 1.2 9.9 5 3 2 8 8 6 2 Bacterial protein of unknown function (DUF948) HAMP_N3 PF18575.1 EGG10558.1 - 0.0035 16.9 0.0 23 4.7 0.0 5.1 5 0 0 5 5 5 0 HAMP N-terminal domain 3 WXG100 PF06013.12 EGG10558.1 - 0.0075 16.5 13.5 7.1 6.9 0.2 6.4 5 2 1 6 6 6 1 Proteins of 100 residues with WXG Spt5-NGN PF03439.13 EGG10558.1 - 0.089 12.7 0.1 6.3 6.8 0.1 2.7 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section DUF2118 PF09891.9 EGG10558.1 - 0.092 12.7 2.4 11 5.9 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) Anillin_N PF16018.5 EGG10558.1 - 0.092 13.4 6.0 7.9 7.2 0.1 3.7 4 0 0 4 4 3 0 Anillin N-terminus Cauli_AT PF03233.13 EGG10558.1 - 1.3 8.9 3.1 4.3 7.3 0.0 3.5 4 1 0 4 4 4 0 Aphid transmission protein YdaT_toxin PF06254.11 EGG10558.1 - 2.5 8.7 6.7 4.9 7.8 0.1 4.3 4 1 1 5 5 5 0 Putative bacterial toxin ydaT WD40 PF00400.32 EGG10559.1 - 2.1e-54 180.2 26.4 2.4e-11 44.0 0.6 8.4 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG10559.1 - 1.1e-15 57.7 1.6 1.4e-07 31.7 0.1 5.7 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG10559.1 - 2.4e-11 43.0 8.3 0.017 13.8 0.0 5.9 3 2 2 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGG10559.1 - 3.7e-05 22.7 0.6 0.92 8.2 0.0 3.6 1 1 0 3 3 3 2 Nup133 N terminal like DUF5570 PF17731.1 EGG10559.1 - 0.033 14.3 0.9 1.9 8.6 0.2 3.3 2 1 0 3 3 3 0 Family of unknown function (DUF5570) Cytochrom_D1 PF02239.16 EGG10559.1 - 0.065 11.7 0.1 1.3 7.4 0.0 2.3 2 1 1 3 3 3 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EGG10559.1 - 0.091 11.7 6.1 0.67 8.9 2.3 3.0 2 2 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein bZIP_2 PF07716.15 EGG10559.1 - 0.18 11.9 0.6 0.31 11.1 0.6 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Pox_A_type_inc PF04508.12 EGG10559.1 - 0.39 10.6 3.7 0.14 12.0 0.6 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SUD-M PF11633.8 EGG10562.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain dsrm PF00035.26 EGG10563.1 - 0.036 14.8 2.0 0.2 12.4 0.4 2.3 1 1 1 2 2 2 0 Double-stranded RNA binding motif Thioredoxin_7 PF13899.6 EGG10563.1 - 0.088 13.0 0.5 18 5.6 0.2 2.6 2 0 0 2 2 2 0 Thioredoxin-like DUF5559 PF17714.1 EGG10565.1 - 0.00098 19.1 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5559) LRR_4 PF12799.7 EGG10570.1 - 0.00032 21.0 0.1 0.15 12.6 0.1 3.9 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) FNIP PF05725.12 EGG10570.1 - 0.62 10.3 4.0 12 6.2 0.1 3.6 3 0 0 3 3 3 0 FNIP Repeat KAR PF15222.6 EGG10573.1 - 0.042 14.1 3.3 0.099 12.9 3.3 1.7 1 1 0 1 1 1 0 Kidney androgen-regulated Tmemb_cc2 PF10267.9 EGG10573.1 - 0.5 9.5 2.0 0.65 9.1 2.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Ribosomal_L13 PF00572.18 EGG10577.1 - 3.1e-42 143.7 0.1 4e-42 143.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_L13 PF00572.18 EGG10578.1 - 3.1e-42 143.7 0.1 4e-42 143.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 DUF3511 PF12023.8 EGG10580.1 - 0.1 12.4 0.6 0.18 11.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) DUF4175 PF13779.6 EGG10580.1 - 0.2 9.5 13.8 0.22 9.4 13.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SRP-alpha_N PF04086.13 EGG10580.1 - 4.5 7.1 12.2 5.3 6.9 12.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Paf1 PF03985.13 EGG10580.1 - 4.8 6.1 15.8 5.8 5.8 15.8 1.1 1 0 0 1 1 1 0 Paf1 DUF4746 PF15928.5 EGG10580.1 - 4.9 6.5 8.0 5.3 6.4 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Coilin_N PF15862.5 EGG10580.1 - 6.4 6.6 10.6 2 8.2 7.8 1.8 2 0 0 2 2 2 0 Coilin N-terminus CDC45 PF02724.14 EGG10580.1 - 7.7 4.7 10.8 7.5 4.7 10.8 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EGG10580.1 - 9 6.0 11.6 10 5.8 11.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pribosyltran PF00156.27 EGG10583.1 - 0.081 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Fungal_trans PF04082.18 EGG10584.1 - 8e-15 54.6 1.2 2.1e-14 53.2 1.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGG10584.1 - 2.5e-07 30.7 6.5 4.2e-07 30.0 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1765 PF08578.10 EGG10586.1 - 1.9e-33 115.6 0.5 4.2e-33 114.5 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) An_peroxidase PF03098.15 EGG10587.1 - 3e-23 82.2 0.0 1.5e-10 40.3 0.2 4.1 2 1 0 2 2 2 2 Animal haem peroxidase F-box-like PF12937.7 EGG10589.1 - 0.0034 17.2 0.1 0.0079 16.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG10589.1 - 0.024 14.5 0.6 0.1 12.5 0.1 2.3 2 0 0 2 2 2 0 F-box domain zf-C2H2 PF00096.26 EGG10590.1 - 9e-11 41.6 9.2 8.4e-06 26.0 1.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG10590.1 - 1.3e-06 28.8 8.3 0.003 18.3 1.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGG10590.1 - 0.00021 21.2 5.2 0.079 13.0 0.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGG10590.1 - 0.00067 19.9 1.1 1.3 9.4 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG10590.1 - 0.0046 17.3 4.2 0.61 10.6 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 EGG10590.1 - 0.019 14.9 9.3 0.13 12.2 0.7 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Cript PF10235.9 EGG10590.1 - 0.049 14.2 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-C2HE PF16278.5 EGG10590.1 - 0.095 13.2 2.5 8.3 7.0 0.2 2.5 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 EGG10590.1 - 0.099 13.3 2.5 5.1 7.8 0.2 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats DZR PF12773.7 EGG10590.1 - 0.11 12.5 0.2 0.26 11.3 0.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-H2C2_2 PF13465.6 EGG10590.1 - 0.21 12.1 7.7 0.41 11.2 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger double domain DUF2256 PF10013.9 EGG10590.1 - 0.37 10.9 2.1 16 5.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-BED PF02892.15 EGG10590.1 - 1.3 9.1 6.9 3.1 7.9 1.1 2.5 1 1 1 2 2 2 0 BED zinc finger FYVE PF01363.21 EGG10590.1 - 4.7 7.4 7.0 23 5.2 7.0 1.9 1 1 0 1 1 1 0 FYVE zinc finger OTCace PF00185.24 EGG10591.1 - 1.8e-47 161.3 0.0 3.2e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EGG10591.1 - 4.3e-42 143.6 0.1 6.7e-42 143.0 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain zf-RING_2 PF13639.6 EGG10592.1 - 1.2e-05 25.6 7.1 1.8e-05 25.0 7.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 EGG10592.1 - 0.0002 21.1 8.4 0.00035 20.3 8.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EGG10592.1 - 0.00034 20.4 7.0 0.00057 19.7 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG10592.1 - 0.0029 17.5 7.2 0.0046 16.8 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG10592.1 - 0.043 13.7 7.5 0.07 13.0 7.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 EGG10592.1 - 0.087 12.8 5.3 0.16 11.9 5.3 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 EGG10592.1 - 1.1 9.4 5.1 3.2 7.9 5.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGG10592.1 - 2.3 8.2 8.2 4.3 7.4 8.2 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EGG10593.1 - 7.5e-07 29.4 7.6 1.1e-06 28.9 7.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 EGG10593.1 - 4.5e-06 26.3 6.2 7.6e-06 25.6 6.2 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EGG10593.1 - 2.2e-05 24.2 5.4 3.4e-05 23.6 5.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG10593.1 - 0.00016 21.5 7.2 0.00024 20.9 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG10593.1 - 0.00017 21.4 7.2 0.00026 20.8 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG10593.1 - 0.01 15.8 6.8 0.014 15.3 6.8 1.2 1 0 0 1 1 1 0 zinc-RING finger domain zf-DBF PF07535.12 EGG10593.1 - 0.23 11.6 2.8 0.47 10.6 2.8 1.4 1 0 0 1 1 1 0 DBF zinc finger Prok-RING_4 PF14447.6 EGG10593.1 - 0.8 9.6 6.1 1.4 8.9 6.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGG10593.1 - 1.3 9.1 6.5 3.1 7.9 6.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger GBR2_CC PF18455.1 EGG10594.1 - 0.041 14.0 1.1 0.048 13.8 0.0 1.6 2 0 0 2 2 2 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain DUF2675 PF11247.8 EGG10595.1 - 0.23 11.6 0.0 0.59 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) OTCace PF00185.24 EGG10598.1 - 6.2e-12 45.9 0.0 7e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF5320 PF17253.2 EGG10599.1 - 5.1 8.2 13.8 4.6 8.4 1.8 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5320) ArfGap PF01412.18 EGG10600.1 - 1.3e-41 141.4 0.4 1.7e-41 141.0 0.4 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf OSCP PF00213.18 EGG10602.1 - 1.4e-39 136.0 1.9 1.6e-39 135.8 1.9 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit LXG PF04740.12 EGG10602.1 - 0.024 14.3 0.3 0.071 12.8 0.0 1.7 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF3277 PF11681.8 EGG10602.1 - 0.025 14.5 0.1 0.06 13.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) SPOUT_MTase PF02590.17 EGG10602.1 - 0.095 12.7 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Alpha_kinase PF02816.18 EGG10605.1 - 3.4e-13 50.1 0.6 4.8e-13 49.6 0.6 1.2 1 0 0 1 1 1 1 Alpha-kinase family HMG_box PF00505.19 EGG10610.1 - 9.8e-19 67.5 7.5 3.6e-10 40.1 1.9 3.2 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EGG10610.1 - 1.2e-13 51.4 3.0 3.2e-07 30.8 0.1 2.6 2 0 0 2 2 2 2 HMG-box domain DUF3340 PF11818.8 EGG10610.1 - 2.1 8.5 10.2 1.5 9.0 0.4 2.5 3 0 0 3 3 3 0 C-terminal domain of tail specific protease (DUF3340) DUF3106 PF11304.8 EGG10610.1 - 3.1 8.3 9.7 4.4 7.8 1.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3106) LRR19-TM PF15176.6 EGG10611.1 - 0.33 11.0 4.9 0.96 9.5 0.0 3.8 4 1 1 5 5 5 0 Leucine-rich repeat family 19 TM domain Retrotran_gag_2 PF14223.6 EGG10613.1 - 1.8e-07 30.9 0.0 4.8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4407 PF14362.6 EGG10613.1 - 1.1 8.6 5.5 2 7.7 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIN_4 PF13638.6 EGG10614.1 - 3.1e-21 76.0 2.8 1.4e-20 73.9 2.8 2.2 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.9 EGG10614.1 - 4.2e-07 29.7 1.2 0.00055 19.5 0.2 3.1 2 1 0 2 2 2 2 Est1 DNA/RNA binding domain PIN_9 PF18477.1 EGG10614.1 - 0.0079 16.5 3.3 10 6.5 0.2 3.7 3 0 0 3 3 3 2 PIN like domain Fcf1 PF04900.12 EGG10615.1 - 9.6e-22 77.3 2.5 1.1e-21 77.1 0.0 2.2 2 1 1 3 3 3 1 Fcf1 PIN_9 PF18477.1 EGG10615.1 - 5.2e-08 33.2 0.0 1.3e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 PIN like domain DUF645 PF04875.12 EGG10617.1 - 0.35 11.0 2.4 0.74 9.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF645 zf-C3HC4_2 PF13923.6 EGG10618.1 - 6.6e-07 29.1 7.2 1.9e-06 27.6 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG10618.1 - 2.8e-05 24.4 5.7 0.00011 22.5 5.7 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGG10618.1 - 0.0001 22.0 2.5 0.00027 20.7 2.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG10618.1 - 0.00034 20.6 9.2 0.00092 19.2 9.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG10618.1 - 0.00052 19.8 6.4 0.0017 18.2 6.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGG10618.1 - 0.0047 17.0 4.5 0.016 15.3 4.5 1.9 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 EGG10618.1 - 0.012 15.4 3.4 0.063 13.1 3.4 2.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 EGG10618.1 - 0.022 14.9 0.9 0.12 12.6 0.5 2.5 1 1 1 2 2 2 0 U-box domain zf-RING_6 PF14835.6 EGG10618.1 - 0.1 12.5 2.0 0.21 11.5 2.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EGG10618.1 - 0.19 11.9 8.3 0.69 10.1 8.3 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 EGG10618.1 - 0.46 10.2 9.8 12 5.6 9.8 3.0 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_5 PF14634.6 EGG10618.1 - 1.5 8.8 9.0 0.089 12.8 2.5 2.3 2 0 0 2 2 2 0 zinc-RING finger domain SIR2 PF02146.17 EGG10619.1 - 1.1e-25 90.6 0.0 1.4e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Lectin_leg-like PF03388.13 EGG10620.1 - 4.6e-41 140.6 0.0 6.8e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EGG10620.1 - 8.2e-08 32.5 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EGG10620.1 - 0.043 13.4 0.0 0.18 11.3 0.0 1.8 1 1 0 1 1 1 0 Legume lectin domain NAD_binding_8 PF13450.6 EGG10621.1 - 3.8e-12 46.3 0.0 7.1e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGG10621.1 - 1.7e-07 30.9 0.0 1.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EGG10621.1 - 0.00037 20.2 0.1 0.00054 19.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG10621.1 - 0.0087 15.3 0.0 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG10621.1 - 0.023 14.7 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EGG10621.1 - 0.094 11.4 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EGG10621.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EGG10621.1 - 0.2 10.9 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Antimicrobial_7 PF08102.11 EGG10622.1 - 0.24 11.7 0.6 0.99 9.7 0.0 2.0 2 0 0 2 2 2 0 Scorpion antimicrobial peptide M-factor PF03855.13 EGG10624.1 - 3.4 7.9 5.9 1.8 8.8 0.9 2.6 2 0 0 2 2 2 0 M-factor DUF3568 PF12092.8 EGG10625.1 - 0.16 12.0 2.2 0.32 11.1 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) SWIRM-assoc_2 PF16496.5 EGG10625.1 - 0.51 9.2 3.6 1.1 8.1 3.6 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Integrin_b_cyt PF08725.11 EGG10626.1 - 0.65 9.7 5.3 5.1 6.9 0.7 2.6 1 1 1 2 2 2 0 Integrin beta cytoplasmic domain Bax1-I PF01027.20 EGG10627.1 - 7.1e-43 146.9 28.8 8.4e-43 146.6 28.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF5325 PF17259.2 EGG10627.1 - 4.2 7.3 7.5 0.52 10.2 2.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5325) ATG19_autophagy PF12744.7 EGG10629.1 - 0.0037 16.5 1.0 0.0063 15.7 1.0 1.3 1 0 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding Cadherin_C_2 PF16492.5 EGG10631.1 - 0.054 14.2 0.3 6.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Glyco_transf_25 PF01755.17 EGG10632.1 - 1.2e-10 41.6 0.9 0.00027 20.9 0.2 3.2 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Ehbp PF10622.9 EGG10632.1 - 0.00089 19.2 0.6 0.0068 16.4 0.1 2.4 2 0 0 2 2 2 1 Energy-converting hydrogenase B subunit P (EhbP) Nse4_C PF08743.10 EGG10633.1 - 4.2e-29 100.7 0.6 4.2e-29 100.7 0.6 2.2 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EGG10633.1 - 5.1e-11 42.5 4.8 6.8e-11 42.1 3.3 2.0 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE Diphthamide_syn PF01866.17 EGG10634.1 - 1.9e-83 280.4 0.0 2.3e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Nanovirus_coat PF04660.12 EGG10634.1 - 0.0028 17.7 0.1 0.16 12.0 0.1 2.2 2 0 0 2 2 2 2 Nanovirus coat protein RhoGEF PF00621.20 EGG10635.1 - 8.9e-08 32.6 0.0 1.9e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain PH PF00169.29 EGG10635.1 - 0.046 14.2 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 PH domain PI3_PI4_kinase PF00454.27 EGG10636.1 - 8.7e-39 133.8 0.0 1.3e-38 133.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase REV PF00424.18 EGG10638.1 - 0.6 10.2 5.1 0.27 11.3 0.9 2.5 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) E1_dh PF00676.20 EGG10639.1 - 6.8e-10 38.4 0.0 7.8e-10 38.2 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component MOZ_SAS PF01853.18 EGG10640.1 - 2e-80 268.7 0.4 3.1e-80 268.0 0.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGG10640.1 - 2.5e-22 78.2 1.0 6e-22 77.0 1.0 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EGG10640.1 - 2.2e-10 40.2 0.0 5.5e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EGG10640.1 - 0.0043 17.4 0.0 0.008 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG10640.1 - 0.013 15.7 0.0 0.05 13.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family HTH_6 PF01418.17 EGG10640.1 - 0.014 15.4 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family YIEGIA PF14045.6 EGG10640.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 YIEGIA protein FYDLN_acid PF09538.10 EGG10640.1 - 0.18 12.5 10.7 0.4 11.4 10.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Pox_Ag35 PF03286.14 EGG10640.1 - 0.34 10.7 8.4 0.59 9.9 8.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BNIP2 PF12496.8 EGG10640.1 - 0.71 10.3 9.6 1.3 9.4 9.6 1.4 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Cwf_Cwc_15 PF04889.12 EGG10640.1 - 0.77 9.5 15.5 0.018 14.8 9.2 1.4 2 0 0 2 2 1 0 Cwf15/Cwc15 cell cycle control protein Spt5_N PF11942.8 EGG10640.1 - 8.7 7.4 16.3 0.067 14.2 6.5 2.4 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal EF-hand_1 PF00036.32 EGG10642.1 - 7.5e-27 90.9 8.9 5.2e-09 35.0 0.0 5.0 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EGG10642.1 - 9.2e-27 93.3 6.7 1.6e-19 70.1 0.6 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGG10642.1 - 2.4e-23 80.0 6.4 4.8e-06 26.1 0.2 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EGG10642.1 - 4.2e-16 57.6 7.4 7.5e-05 22.1 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EGG10642.1 - 5.8e-13 48.5 8.5 0.00012 21.8 1.0 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EGG10642.1 - 1.2e-07 31.7 2.2 0.0093 15.9 0.0 3.9 2 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGG10642.1 - 6.3e-06 26.5 1.6 0.048 14.0 0.2 3.2 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGG10642.1 - 0.0018 18.6 0.9 0.083 13.2 0.0 3.0 2 1 1 3 3 3 1 EF-hand domain PMBR PF09373.10 EGG10642.1 - 0.067 13.4 0.1 21 5.5 0.0 3.3 4 0 0 4 4 4 0 Pseudomurein-binding repeat Pan3_PK PF18101.1 EGG10642.1 - 0.097 12.7 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Pan3 Pseudokinase domain EF-hand_14 PF17959.1 EGG10642.1 - 0.11 12.9 1.2 1.4 9.3 0.1 2.8 3 1 0 3 3 3 0 EF-hand domain p25-alpha PF05517.12 EGG10642.1 - 0.13 12.5 2.5 7.4 6.7 0.1 2.4 1 1 0 2 2 2 0 p25-alpha EF-hand_2 PF09068.11 EGG10642.1 - 0.14 12.3 0.3 3.4 7.8 0.0 2.6 3 0 0 3 3 3 0 EF hand Caleosin PF05042.13 EGG10642.1 - 0.42 10.5 4.3 16 5.3 0.0 3.3 3 1 1 4 4 4 0 Caleosin related protein F-box-like PF12937.7 EGG10643.1 - 0.018 14.9 2.2 0.02 14.8 0.3 2.1 2 0 0 2 2 2 0 F-box-like DHHA2 PF02833.14 EGG10644.1 - 2.2e-27 96.0 0.3 5e-27 94.8 0.2 1.6 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 EGG10644.1 - 3.6e-11 43.2 0.0 6.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 DHH family 7tm_6 PF02949.20 EGG10645.1 - 0.078 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 7tm Odorant receptor Dfp1_Him1_M PF08630.10 EGG10646.1 - 4e-31 107.9 0.9 2e-30 105.6 0.1 2.5 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 EGG10646.1 - 3.5e-19 68.6 0.3 8.2e-19 67.5 0.3 1.7 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 EGG10646.1 - 0.0011 19.3 0.1 0.0054 17.1 0.1 2.3 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGG10646.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain DUF3439 PF11921.8 EGG10646.1 - 0.68 9.9 5.3 1.9 8.5 5.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PLA2_B PF01735.18 EGG10647.1 - 7.4e-100 334.7 0.1 4.6e-91 305.7 0.0 2.1 1 1 1 2 2 2 2 Lysophospholipase catalytic domain Hexapep PF00132.24 EGG10648.1 - 1.4e-11 43.6 19.1 1.9e-07 30.6 3.6 5.0 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGG10648.1 - 2.1e-08 33.8 11.3 0.00012 21.8 2.8 3.6 3 1 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EGG10648.1 - 0.0018 17.3 0.2 0.0027 16.7 0.2 1.2 1 0 0 1 1 1 1 L-fucokinase VapB_antitoxin PF09957.9 EGG10649.1 - 0.14 12.1 0.3 0.25 11.3 0.3 1.4 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB Phasin PF05597.11 EGG10650.1 - 0.0041 17.1 1.7 0.91 9.5 0.6 3.5 3 1 0 3 3 3 1 Poly(hydroxyalcanoate) granule associated protein (phasin) NPV_P10 PF05531.12 EGG10650.1 - 0.0082 16.6 7.0 0.082 13.4 2.4 3.1 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 EGG10650.1 - 0.015 15.4 0.8 0.1 12.6 0.3 2.2 2 0 0 2 2 2 0 Laminin Domain II Collagen_mid PF15984.5 EGG10650.1 - 0.02 14.7 0.3 0.042 13.6 0.3 1.5 1 0 0 1 1 1 0 Bacterial collagen, middle region Nup54 PF13874.6 EGG10650.1 - 0.031 14.4 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 BLOC1_2 PF10046.9 EGG10650.1 - 0.092 13.1 1.3 0.4 11.0 0.4 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_N PF02465.18 EGG10650.1 - 0.1 13.3 1.7 0.24 12.1 1.7 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus CorA PF01544.18 EGG10650.1 - 0.15 11.3 0.4 0.25 10.6 0.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FlaC_arch PF05377.11 EGG10650.1 - 0.31 11.5 1.2 1.9 9.0 1.2 2.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) LPP PF04728.13 EGG10650.1 - 2.4 8.6 7.2 22 5.6 1.0 3.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF3671 PF12420.8 EGG10651.1 - 0.59 10.2 2.2 3 8.0 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function BAG PF02179.16 EGG10652.1 - 3.9e-16 59.3 1.2 6.8e-16 58.5 1.2 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 EGG10652.1 - 3.3e-05 23.6 0.1 0.001 18.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGG10652.1 - 0.0019 18.6 1.2 0.066 13.7 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin-like domain Pkinase PF00069.25 EGG10653.1 - 3.9e-59 200.2 0.0 4.6e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG10653.1 - 1.2e-39 136.2 0.0 1.5e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG10653.1 - 6.6e-05 22.4 0.0 9.6e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGG10653.1 - 0.00013 20.8 0.0 0.00042 19.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EGG10653.1 - 0.00065 18.7 0.0 0.067 12.1 0.0 2.2 1 1 0 2 2 2 2 Haspin like kinase domain Alpha_E3_glycop PF01563.16 EGG10653.1 - 0.034 14.2 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein Chal_sti_synt_C PF02797.15 EGG10653.1 - 0.089 12.8 0.2 0.44 10.5 0.0 2.2 2 1 0 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain Pectinesterase PF01095.19 EGG10654.1 - 2.7e-31 108.4 0.0 3.3e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Pectinesterase Na_Ca_ex PF01699.24 EGG10655.1 - 1.7 8.6 9.5 0.49 10.3 5.1 2.3 2 1 0 2 2 2 0 Sodium/calcium exchanger protein DUF2577 PF10844.8 EGG10657.1 - 0.19 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) Complex1_LYR_2 PF13233.6 EGG10660.1 - 2.7e-12 47.3 0.1 3.2e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Metallothio_11 PF02066.15 EGG10661.1 - 0.017 15.3 0.4 0.048 13.9 0.4 1.8 1 0 0 1 1 1 0 Metallothionein family 11 Lectin_leg-like PF03388.13 EGG10662.1 - 1.3e-61 207.9 0.1 1.8e-61 207.4 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EGG10662.1 - 4e-11 43.3 0.1 6.7e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EGG10662.1 - 3.7e-05 23.4 0.3 0.00045 19.8 0.3 2.1 1 1 0 1 1 1 1 Legume lectin domain DUF2518 PF10726.9 EGG10662.1 - 0.41 10.3 1.9 0.75 9.4 1.9 1.3 1 0 0 1 1 1 0 Protein of function (DUF2518) AhpC-TSA_2 PF13911.6 EGG10663.1 - 1.3e-12 47.9 0.1 4.2e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGG10663.1 - 3.8e-07 30.1 0.0 8.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family CRC_subunit PF08624.10 EGG10664.1 - 2.3e-36 125.2 0.0 5e-36 124.1 0.0 1.6 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit OmpH PF03938.14 EGG10664.1 - 4.6 7.6 16.1 12 6.3 16.1 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_L39 PF00832.20 EGG10665.1 - 4.5e-21 74.2 7.2 5.5e-21 73.9 7.2 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein CEP19 PF14933.6 EGG10666.1 - 7.7 6.8 7.4 2.4 8.5 2.3 2.5 2 1 1 3 3 3 0 CEP19-like protein COMPASS-Shg1 PF05205.12 EGG10667.1 - 1.8e-07 31.8 1.9 3.1e-07 31.1 0.6 2.1 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 Vps26 PF03643.15 EGG10668.1 - 1.5e-127 424.3 4.1 1.7e-127 424.1 4.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 CAP_N PF01213.19 EGG10669.1 - 4 6.8 6.1 6.9 6.1 6.1 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EGG10669.1 - 5.1 7.1 11.8 2 8.5 4.7 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator DPBB_1 PF03330.18 EGG10672.1 - 6.2e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Pterin_bind PF00809.22 EGG10677.1 - 6.2e-31 107.9 0.2 9.7e-31 107.3 0.2 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EGG10677.1 - 3.2e-24 85.6 0.0 5.6e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) adh_short PF00106.25 EGG10678.1 - 5.1e-16 58.7 1.5 5.9e-16 58.5 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG10678.1 - 1.7e-11 44.1 0.9 2.1e-11 43.8 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG10678.1 - 0.012 15.5 0.4 0.016 15.1 0.4 1.1 1 0 0 1 1 1 0 KR domain Ldh_1_N PF00056.23 EGG10678.1 - 0.017 15.3 1.0 0.023 14.8 1.0 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Methyltr_RsmB-F PF01189.17 EGG10678.1 - 0.047 13.3 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F ADH_zinc_N PF00107.26 EGG10678.1 - 0.075 13.0 0.9 0.29 11.1 0.4 1.9 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Arginase PF00491.21 EGG10681.1 - 0.07 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Arginase family Pkinase PF00069.25 EGG10682.1 - 4.8e-05 22.8 0.1 5.6e-05 22.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain DUF4315 PF14193.6 EGG10684.1 - 0.18 11.8 1.7 0.36 10.9 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Glyco_hydro_85 PF03644.13 EGG10685.1 - 0.048 13.1 0.1 0.073 12.5 0.1 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 85 PolyA_pol PF01743.20 EGG10689.1 - 2.3e-07 31.3 0.2 3.4e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain PI3K_1B_p101 PF10486.9 EGG10691.1 - 0.68 7.7 27.6 1 7.1 27.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 EGG10691.1 - 0.94 8.0 38.4 0.095 11.2 33.9 1.5 2 0 0 2 2 2 0 Macoilin family LAP1C PF05609.12 EGG10691.1 - 5 6.1 27.8 10 5.1 27.8 1.5 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GldM_C PF12080.8 EGG10692.1 - 0.03 14.5 0.1 0.086 13.1 0.0 1.7 2 0 0 2 2 2 0 GldM C-terminal domain Ribos_L4_asso_C PF14374.6 EGG10693.1 - 0.068 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain PHD_4 PF16866.5 EGG10693.1 - 0.086 12.9 2.4 0.16 12.1 2.4 1.4 1 0 0 1 1 1 0 PHD-finger Helitron_like_N PF14214.6 EGG10694.1 - 0.016 15.4 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus W2 PF02020.18 EGG10695.1 - 3.8e-18 65.4 0.2 1.3e-17 63.7 0.2 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon RasGEF PF00617.19 EGG10696.1 - 1.2e-61 208.0 0.7 6.5e-61 205.6 0.0 2.2 2 1 1 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 EGG10696.1 - 8.8e-26 90.2 0.0 1.9e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Alpha_kinase PF02816.18 EGG10697.1 - 1e-29 104.0 0.8 1.6e-29 103.3 0.8 1.3 1 0 0 1 1 1 1 Alpha-kinase family zf-C4pol PF14260.6 EGG10697.1 - 8.7 6.9 9.8 5.6 7.5 0.7 3.8 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta HAD_2 PF13419.6 EGG10698.1 - 1.1e-16 61.4 0.0 5e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG10698.1 - 1.6e-13 51.5 0.0 3.3e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGG10698.1 - 2.4e-05 24.3 0.0 5.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EGG10698.1 - 0.021 15.2 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGG10699.1 - 1.6e-16 60.9 0.0 7.3e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG10699.1 - 1.3e-13 51.7 0.0 3e-13 50.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGG10699.1 - 6.3e-06 26.2 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EGG10699.1 - 0.021 15.2 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Chorion_2 PF03964.15 EGG10699.1 - 0.1 13.5 1.0 4.9 8.0 1.4 2.5 2 0 0 2 2 2 0 Chorion family 2 CPSase_sm_chain PF00988.22 EGG10701.1 - 2.3e-43 147.1 0.0 4e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EGG10701.1 - 1.2e-37 129.6 0.0 1.7e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGG10701.1 - 6.1e-08 32.7 0.6 7.8e-06 25.8 0.6 3.0 1 1 0 1 1 1 1 Peptidase C26 SNF2_N PF00176.23 EGG10702.1 - 1.3e-59 201.7 1.3 2.2e-59 200.9 1.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 EGG10702.1 - 1.1e-19 70.6 0.7 4.3e-19 68.7 0.7 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 EGG10702.1 - 1.5e-19 70.3 0.3 6e-19 68.4 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Chromo PF00385.24 EGG10702.1 - 1.1e-16 60.4 7.6 2.6e-13 49.7 0.2 3.5 2 1 1 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 EGG10702.1 - 4e-07 30.2 0.1 1.5e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG10702.1 - 3.5e-06 26.9 0.0 7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CDH1_2_SANT_HL1 PF18375.1 EGG10702.1 - 0.00022 21.9 0.4 0.00022 21.9 0.4 2.8 2 1 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 Cdh1_DBD_1 PF18196.1 EGG10702.1 - 0.00025 21.3 0.3 0.00025 21.3 0.3 4.5 4 1 1 5 5 5 1 Chromodomain helicase DNA-binding domain 1 CHDCT2 PF08074.11 EGG10702.1 - 0.029 14.5 0.8 0.14 12.3 0.0 2.7 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain GPI-anchored PF10342.9 EGG10703.1 - 1.8e-07 31.8 0.4 1.8e-07 31.8 0.4 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 EGG10704.1 - 1.1e-07 32.5 0.3 1.1e-07 32.5 0.3 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family V-ATPase_H_N PF03224.14 EGG10705.1 - 2.2e-67 227.6 2.6 2.2e-67 227.6 2.6 1.9 2 1 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EGG10705.1 - 1e-43 148.2 0.6 5.2e-41 139.4 0.1 2.9 3 0 0 3 3 3 2 V-ATPase subunit H Arm_2 PF04826.13 EGG10705.1 - 0.0028 17.2 0.0 0.0028 17.2 0.0 2.3 3 0 0 3 3 3 1 Armadillo-like HA2 PF04408.23 EGG10707.1 - 4.6e-16 59.1 0.0 1.3e-15 57.6 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGG10707.1 - 4.9e-16 59.1 0.3 2.1e-15 57.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG10707.1 - 3.5e-09 36.7 0.0 9.2e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EGG10707.1 - 4.9e-08 33.2 0.0 1.3e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EGG10707.1 - 2e-06 28.1 0.1 6.7e-06 26.4 0.1 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGG10707.1 - 0.0022 18.5 1.1 0.0068 16.9 0.0 2.5 3 0 0 3 3 3 1 ABC transporter AAA_19 PF13245.6 EGG10707.1 - 0.0037 17.6 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EGG10707.1 - 0.015 15.2 0.3 1.4 8.8 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 EGG10707.1 - 0.036 13.8 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGG10707.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 EGG10707.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase PLA2_B PF01735.18 EGG10708.1 - 8.4e-90 301.5 4.9 8.9e-74 248.7 0.0 3.0 2 1 0 2 2 2 2 Lysophospholipase catalytic domain ZZ PF00569.17 EGG10711.1 - 1.9e-14 53.2 30.5 4e-10 39.3 3.0 3.4 4 0 0 4 4 4 2 Zinc finger, ZZ type zf-C3HC4_2 PF13923.6 EGG10711.1 - 3.5e-07 29.9 8.2 3.5e-07 29.9 8.2 3.7 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG10711.1 - 4.6e-07 29.6 8.2 4.6e-07 29.6 8.2 4.6 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG10711.1 - 1e-06 28.9 9.1 1e-06 28.9 9.1 3.9 3 1 0 3 3 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG10711.1 - 2.9e-06 27.2 9.2 2.9e-06 27.2 9.2 3.3 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGG10711.1 - 4.6e-06 26.4 3.1 4.6e-06 26.4 3.1 4.5 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGG10711.1 - 2.2e-05 24.6 7.4 2.2e-05 24.6 7.4 3.1 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGG10711.1 - 2.4e-05 24.2 4.5 2.4e-05 24.2 4.5 4.1 4 1 0 4 4 2 1 zinc-RING finger domain U-box PF04564.15 EGG10711.1 - 0.0013 18.8 0.1 0.004 17.3 0.1 1.8 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.6 EGG10711.1 - 0.0021 17.9 7.2 0.0021 17.9 7.2 4.0 3 2 1 4 4 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EGG10711.1 - 0.0081 16.0 2.1 0.0081 16.0 2.1 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 EGG10711.1 - 0.0082 15.9 4.4 0.0082 15.9 4.4 2.3 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit bZIP_1 PF00170.21 EGG10711.1 - 0.011 15.8 2.7 0.022 14.9 2.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF2353 PF09789.9 EGG10711.1 - 0.014 14.7 1.3 0.021 14.2 1.3 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Fib_alpha PF08702.10 EGG10711.1 - 0.026 14.7 3.0 0.041 14.1 3.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family zf-RING_10 PF16685.5 EGG10711.1 - 0.032 14.3 3.5 0.032 14.3 3.5 3.3 3 0 0 3 3 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EGG10711.1 - 0.04 14.1 7.8 0.04 14.1 7.8 3.2 3 1 1 4 4 2 0 zinc finger of C3HC4-type, RING LMBR1 PF04791.16 EGG10711.1 - 0.49 9.2 2.2 0.69 8.8 2.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein C1_2 PF03107.16 EGG10711.1 - 3.4 8.1 35.2 0.11 12.9 7.6 4.0 3 1 0 3 3 3 0 C1 domain zf-RING_11 PF17123.5 EGG10713.1 - 2.6e-07 30.2 3.8 5.8e-07 29.1 3.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGG10713.1 - 1.5e-05 25.2 3.9 3.3e-05 24.1 3.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG10713.1 - 0.043 13.9 3.6 0.093 12.8 3.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-4CXXC_R1 PF10497.9 EGG10713.1 - 0.043 14.0 0.2 0.092 13.0 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF2420 PF10336.9 EGG10713.1 - 0.096 12.7 0.1 1.3 9.1 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2420) DIOX_N PF14226.6 EGG10714.1 - 3.8e-27 95.4 0.0 6e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGG10714.1 - 5.9e-17 62.0 0.0 1.6e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tubulin PF00091.25 EGG10715.1 - 4.2e-52 177.2 0.0 6.2e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGG10715.1 - 4e-35 120.7 0.0 6.2e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGG10715.1 - 0.0011 19.2 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGG10715.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGG10715.1 - 0.06 12.5 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Tubulin like CxC1 PF18802.1 EGG10716.1 - 2.2e-24 85.6 0.0 3.9e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG10716.1 - 6.5e-06 26.3 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG10716.1 - 0.0036 17.1 0.3 0.025 14.4 0.1 2.4 2 1 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGG10716.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase Myb_Cef PF11831.8 EGG10718.1 - 2.8e-64 217.0 0.0 2.8e-64 217.0 0.0 3.7 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EGG10718.1 - 6.7e-21 74.2 12.7 5.5e-11 42.5 1.3 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG10718.1 - 3.2e-20 72.1 8.1 3.6e-13 49.5 3.6 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain KIP1 PF07765.12 EGG10718.1 - 1.6 8.9 8.5 0.14 12.3 1.0 3.3 3 0 0 3 3 3 0 KIP1-like protein PPR_2 PF13041.6 EGG10719.1 - 0.00072 19.7 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 PPR repeat family Borrelia_orfX PF04160.12 EGG10720.1 - 2.9 7.9 7.6 0.2 11.6 0.8 2.4 3 0 0 3 3 3 0 Orf-X protein DUF1699 PF08004.11 EGG10721.1 - 0.0083 15.8 0.8 5.1 6.8 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1699) Amidase PF01425.21 EGG10721.1 - 0.15 11.0 0.5 6.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Amidase HTH_50 PF18024.1 EGG10721.1 - 0.18 11.4 1.8 4.5 6.9 0.1 3.1 2 0 0 2 2 2 0 Helix-turn-helix domain Nop25 PF09805.9 EGG10721.1 - 0.85 10.1 5.7 5.6 7.4 1.4 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Nro1 PF12753.7 EGG10722.1 - 0.0044 16.0 3.4 0.028 13.4 3.4 2.0 1 1 0 1 1 1 1 Nuclear pore complex subunit Nro1 CitMHS PF03600.16 EGG10724.1 - 0.24 10.6 1.4 0.37 9.9 1.4 1.2 1 0 0 1 1 1 0 Citrate transporter zf-CCCH PF00642.24 EGG10726.1 - 1.6e-13 50.2 13.2 8.6e-07 28.7 1.3 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGG10726.1 - 0.00012 22.0 8.9 0.00077 19.4 1.1 2.6 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EGG10726.1 - 0.0031 18.2 1.5 0.61 10.8 0.2 2.5 2 0 0 2 2 2 2 Torus domain DUF2083 PF09856.9 EGG10728.1 - 0.054 13.3 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) HSBP1 PF06825.12 EGG10729.1 - 9.8e-05 22.1 0.6 0.017 14.9 0.4 2.4 2 0 0 2 2 2 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 EGG10729.1 - 0.00018 21.5 0.9 0.00088 19.3 0.2 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 EGG10729.1 - 0.0033 17.4 0.9 0.0064 16.5 0.2 1.9 2 0 0 2 2 2 1 Laminin Domain II Syntaxin_2 PF14523.6 EGG10729.1 - 0.0056 17.0 4.5 0.015 15.6 1.5 2.5 2 0 0 2 2 2 1 Syntaxin-like protein ApoLp-III PF07464.11 EGG10729.1 - 0.0081 16.3 1.5 0.012 15.7 0.1 2.0 3 0 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) NPV_P10 PF05531.12 EGG10729.1 - 0.01 16.3 1.7 0.029 14.8 0.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 EGG10729.1 - 0.024 14.9 1.7 0.054 13.8 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) T3SSipB PF16535.5 EGG10729.1 - 0.029 14.9 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 Type III cell invasion protein SipB Apolipoprotein PF01442.18 EGG10729.1 - 0.03 14.2 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 EGG10729.1 - 0.05 13.6 1.5 0.51 10.4 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HsbA PF12296.8 EGG10729.1 - 0.055 13.9 0.3 0.12 12.8 0.3 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A SKA2 PF16740.5 EGG10729.1 - 0.082 12.7 0.3 0.19 11.5 0.3 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Collagen_mid PF15984.5 EGG10729.1 - 0.096 12.4 0.1 0.28 10.9 0.1 1.8 1 0 0 1 1 1 0 Bacterial collagen, middle region CREPT PF16566.5 EGG10729.1 - 0.14 12.3 0.3 0.45 10.7 0.1 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4795 PF16043.5 EGG10729.1 - 0.16 11.6 0.1 0.61 9.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4776 PF16003.5 EGG10730.1 - 0.051 12.6 25.3 0.077 12.0 25.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) TERB2 PF15101.6 EGG10730.1 - 3.2 7.8 20.0 2.7 8.0 3.5 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF1682 PF07946.14 EGG10731.1 - 0.096 11.9 11.8 0.13 11.5 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3807 PF12720.7 EGG10731.1 - 2.7 8.2 37.5 0.12 12.7 22.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) U79_P34 PF03064.16 EGG10731.1 - 3.8 6.8 24.3 7.7 5.8 24.3 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FKBP_C PF00254.28 EGG10732.1 - 2.4e-32 111.1 0.0 5.9e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NARP1 PF12569.8 EGG10732.1 - 0.58 9.0 9.1 0.76 8.6 9.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 EGG10732.1 - 1.5 7.5 2.4 1.5 7.5 2.4 1.0 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 EGG10732.1 - 1.6 7.0 7.2 2 6.6 7.2 1.1 1 0 0 1 1 1 0 Menin ATP11 PF06644.11 EGG10732.1 - 4.8 6.9 8.0 6.2 6.5 8.0 1.1 1 0 0 1 1 1 0 ATP11 protein DUF2570 PF10828.8 EGG10733.1 - 0.075 12.9 0.6 0.13 12.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) TACI-CRD2 PF09305.10 EGG10734.1 - 0.22 11.6 0.5 33 4.6 0.0 2.7 3 0 0 3 3 3 0 TACI, cysteine-rich domain TAT_signal PF10518.9 EGG10734.1 - 0.28 11.1 0.6 0.43 10.5 0.6 1.3 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence MFS_1 PF07690.16 EGG10739.1 - 3.1e-22 79.0 26.3 5e-22 78.3 26.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily LRR_4 PF12799.7 EGG10740.1 - 7.3e-11 42.1 26.8 0.00033 21.0 0.8 5.7 3 2 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG10740.1 - 8.7e-08 31.8 26.1 3.9e-05 23.3 4.8 4.8 5 2 0 5 5 5 2 Leucine rich repeat LRR_9 PF14580.6 EGG10740.1 - 2.8e-07 30.2 4.2 0.00064 19.3 1.1 3.0 2 1 1 3 3 3 2 Leucine-rich repeat SMN PF06003.12 EGG10740.1 - 0.028 13.7 2.3 0.055 12.7 2.3 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) TRPM_tetra PF16519.5 EGG10740.1 - 0.11 12.6 2.3 10 6.3 0.2 2.7 2 0 0 2 2 2 0 Tetramerisation domain of TRPM LRR_6 PF13516.6 EGG10740.1 - 0.2 11.8 13.0 2.6 8.3 0.0 5.7 5 0 0 5 5 5 0 Leucine Rich repeat DUF3292 PF11696.8 EGG10741.1 - 2.7e-18 65.7 8.1 5.9e-09 34.9 0.2 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3292) MmgE_PrpD PF03972.14 EGG10742.1 - 7e-153 509.3 0.0 8.4e-153 509.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Presenilin PF01080.17 EGG10743.1 - 3.3 6.4 4.8 5 5.8 4.8 1.2 1 0 0 1 1 1 0 Presenilin DUF1168 PF06658.12 EGG10745.1 - 3.6e-26 91.6 38.8 1.8e-25 89.4 34.4 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1168) DUF4476 PF14771.6 EGG10745.1 - 0.022 15.1 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) DUF2514 PF10721.9 EGG10746.1 - 0.086 12.9 0.8 0.11 12.6 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Vps8 PF12816.7 EGG10747.1 - 2.6e-67 226.2 0.9 9.5e-66 221.1 0.1 3.2 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EGG10747.1 - 0.013 15.4 0.1 0.34 10.8 0.0 3.0 3 0 0 3 3 3 0 Region in Clathrin and VPS Syntaxin-5_N PF11416.8 EGG10747.1 - 0.11 11.8 0.0 0.27 10.5 0.0 1.7 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain LRR19-TM PF15176.6 EGG10750.1 - 0.07 13.1 1.1 0.34 10.9 0.0 2.6 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain F-box-like PF12937.7 EGG10751.1 - 0.026 14.4 0.1 0.086 12.7 0.0 1.9 2 0 0 2 2 2 0 F-box-like Inhibitor_I9 PF05922.16 EGG10752.1 - 5.4e-10 39.8 0.0 2e-09 38.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 Arrestin_C PF02752.22 EGG10754.1 - 1.1e-14 55.0 0.5 7.3e-13 49.1 0.2 3.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGG10754.1 - 1.5e-07 31.5 0.0 3.6e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EGG10754.1 - 0.0064 16.2 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Nore1-SARAH PF16517.5 EGG10755.1 - 9.1 6.3 6.5 0.41 10.6 0.5 1.8 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain FSA_C PF10479.9 EGG10757.1 - 0.024 12.8 2.9 0.032 12.4 2.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PIEZO PF15917.5 EGG10757.1 - 0.51 9.8 2.9 0.19 11.1 0.4 1.5 2 0 0 2 2 2 0 Piezo Tup_N PF08581.10 EGG10758.1 - 9e-06 25.9 5.3 9e-06 25.9 5.3 5.9 5 1 0 6 6 6 1 Tup N-terminal DUF3130 PF11328.8 EGG10758.1 - 0.95 9.8 7.5 0.28 11.5 0.8 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3130 Laminin_II PF06009.12 EGG10758.1 - 3.3 7.7 34.6 0.27 11.3 3.9 5.2 2 2 2 6 6 6 0 Laminin Domain II GMC_oxred_N PF00732.19 EGG10759.1 - 2e-59 201.4 0.0 2.7e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGG10759.1 - 1.7e-29 103.2 0.0 2.7e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EGG10759.1 - 0.00079 18.6 0.3 0.0011 18.0 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EGG10759.1 - 0.0024 17.1 0.1 0.0046 16.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EGG10759.1 - 0.011 15.4 0.4 0.14 11.7 0.4 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGG10759.1 - 0.036 13.1 0.5 3.9 6.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 EGG10759.1 - 0.12 11.2 0.2 0.17 10.7 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 EGG10759.1 - 0.12 11.5 0.0 0.69 9.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG10759.1 - 0.17 12.1 0.2 0.46 10.8 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ATP-sulfurylase PF01747.17 EGG10761.1 - 1.3e-82 276.4 0.0 2e-82 275.8 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EGG10761.1 - 7.3e-48 162.2 0.0 1.1e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 EGG10761.1 - 0.004 17.1 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase HAP1_N PF04849.13 EGG10762.1 - 1.2e-05 24.7 0.6 1.2e-05 24.7 0.6 4.0 3 1 0 4 4 4 2 HAP1 N-terminal conserved region NPV_P10 PF05531.12 EGG10762.1 - 0.14 12.6 1.6 1.8 9.1 0.2 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GCN5L1 PF06320.13 EGG10762.1 - 0.2 11.8 6.7 0.038 14.2 1.9 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) IL2 PF00715.17 EGG10762.1 - 1.2 9.1 6.5 5 7.1 0.2 2.9 3 0 0 3 3 3 0 Interleukin 2 DUF1664 PF07889.12 EGG10762.1 - 1.7 8.7 7.9 0.35 10.9 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 EGG10762.1 - 4.8 6.4 14.0 3.2 7.0 3.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4094 PF13334.6 EGG10762.1 - 5.4 7.5 8.6 3.1 8.3 3.8 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF2203 PF09969.9 EGG10762.1 - 7.6 7.3 12.6 0.52 11.1 1.0 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Acetyltransf_7 PF13508.7 EGG10763.1 - 0.068 13.6 0.0 0.071 13.5 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Gln-synt_C PF00120.24 EGG10764.1 - 1.1e-13 50.9 0.0 2.1e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EGG10764.1 - 1.3e-11 44.0 0.0 2.3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SEO_N PF14576.6 EGG10765.1 - 4.9 6.2 6.3 7.6 5.6 0.2 2.6 2 1 1 3 3 3 0 Sieve element occlusion N-terminus RRM_1 PF00076.22 EGG10767.1 - 0.0018 18.0 0.1 0.0045 16.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 EGG10767.1 - 0.16 12.0 0.1 0.42 10.7 0.1 1.8 1 1 0 1 1 1 0 RNA binding domain ARPC4 PF05856.12 EGG10768.1 - 1.7e-74 249.0 0.5 1.9e-74 248.8 0.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) NAD_binding_6 PF08030.12 EGG10769.1 - 3.1e-19 69.6 0.6 5e-19 68.9 0.6 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGG10769.1 - 1.9e-16 60.3 12.9 1.9e-16 60.3 12.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGG10769.1 - 1.6e-14 53.9 0.0 1.9e-10 40.8 0.0 2.6 1 1 1 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 EGG10769.1 - 0.00066 20.3 0.3 0.035 14.8 0.0 2.5 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain TPPK_C PF12555.8 EGG10769.1 - 0.49 10.5 3.2 5.9 7.0 0.5 2.9 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF4405 PF14358.6 EGG10769.1 - 7.5 7.2 12.4 11 6.7 1.5 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) Cid2 PF09774.9 EGG10773.1 - 4.8e-26 92.1 4.4 5.7e-26 91.8 4.4 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 CGI-121 PF08617.10 EGG10774.1 - 2.8e-43 147.8 4.1 3.3e-43 147.6 4.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Thioredoxin PF00085.20 EGG10775.1 - 8.4e-25 86.8 0.2 1.2e-24 86.2 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGG10775.1 - 2.6e-06 27.8 0.3 0.00011 22.7 0.3 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGG10775.1 - 1.1e-05 25.7 0.1 0.02 15.2 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 EGG10775.1 - 0.00017 21.4 0.1 0.00024 20.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EGG10775.1 - 0.00021 20.8 0.1 0.00023 20.6 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGG10775.1 - 0.0019 18.3 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EGG10775.1 - 0.002 18.1 0.1 0.041 13.8 0.0 2.1 1 1 1 2 2 2 1 AhpC/TSA family DIM1 PF02966.16 EGG10775.1 - 0.0038 17.0 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF953 PF06110.11 EGG10775.1 - 0.0071 16.0 0.3 0.047 13.3 0.3 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Redoxin PF08534.10 EGG10775.1 - 0.023 14.4 0.3 0.38 10.5 0.1 2.1 1 1 1 2 2 2 0 Redoxin SecY PF00344.20 EGG10776.1 - 1.6e-73 247.6 7.6 2.3e-73 247.1 7.6 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EGG10776.1 - 1.5e-19 69.5 0.2 9.1e-19 67.0 0.2 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p QCR10 PF09796.9 EGG10776.1 - 0.45 10.6 1.8 2.5 8.2 0.0 3.1 4 0 0 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Retrotran_gag_2 PF14223.6 EGG10777.1 - 9.6e-05 22.1 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4347 PF14252.6 EGG10777.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) BLI1 PF17324.2 EGG10777.1 - 0.13 13.0 0.1 0.22 12.2 0.1 1.3 1 0 0 1 1 1 0 BLOC-1 interactor 1 GAGA PF09237.11 EGG10778.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 GAGA factor Lactonase PF10282.9 EGG10784.1 - 1.2e-17 64.3 0.0 1.9e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SH3_6 PF12913.7 EGG10784.1 - 0.12 12.0 0.0 0.48 10.0 0.0 2.0 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) zf-CCCH PF00642.24 EGG10785.1 - 1.2e-08 34.7 24.1 7.7e-05 22.5 6.7 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.6 EGG10785.1 - 9.7e-07 29.0 8.1 9.7e-07 29.0 8.1 2.5 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGG10785.1 - 4.8e-06 26.3 6.3 1.1e-05 25.2 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG10785.1 - 0.0002 21.3 4.1 0.0002 21.3 4.1 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGG10785.1 - 0.0006 19.6 7.5 0.0019 18.0 7.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG10785.1 - 0.0026 17.5 3.0 0.0026 17.5 3.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG10785.1 - 0.0028 17.6 6.4 0.0056 16.6 6.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Torus PF16131.5 EGG10785.1 - 0.0045 17.7 3.8 0.83 10.4 0.5 2.6 2 0 0 2 2 2 2 Torus domain zf-rbx1 PF12678.7 EGG10785.1 - 0.0092 16.2 6.4 0.034 14.4 6.4 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGG10785.1 - 0.043 14.0 8.4 0.097 12.8 8.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGG10785.1 - 0.044 13.6 5.9 0.15 12.0 5.9 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Inhibitor_I36 PF03995.13 EGG10785.1 - 0.078 12.9 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Peptidase inhibitor family I36 zf_CCCH_4 PF18345.1 EGG10785.1 - 0.094 12.8 28.6 0.44 10.7 9.8 2.5 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 EGG10785.1 - 0.23 11.3 22.9 1.1 9.2 8.1 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EGG10785.1 - 0.55 10.8 21.4 1.1 9.8 9.2 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF1344 PF07076.11 EGG10786.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) OPT PF03169.15 EGG10787.1 - 2.6e-124 416.2 41.4 5.7e-124 415.0 41.4 1.6 1 1 0 1 1 1 1 OPT oligopeptide transporter protein GSCFA PF08885.11 EGG10788.1 - 0.028 14.1 0.6 1.9 8.1 0.1 2.2 1 1 1 2 2 2 0 GSCFA family Sad1_UNC PF07738.13 EGG10789.1 - 3.2e-29 101.6 0.0 4.3e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal NADHdeh_related PF10125.9 EGG10789.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein ORC6 PF05460.13 EGG10790.1 - 0.076 12.3 7.5 0.024 13.9 4.4 1.8 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF3220 PF11516.8 EGG10790.1 - 0.091 13.0 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) Ribonuc_red_sm PF00268.21 EGG10794.1 - 1.2e-24 87.2 0.1 1.7e-24 86.7 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain AFT PF08731.11 EGG10796.1 - 0.023 15.1 8.8 0.29 11.6 0.0 3.4 3 1 0 3 3 3 0 Transcription factor AFT Cut8 PF08559.10 EGG10797.1 - 1.3e-16 61.0 3.8 2.9e-16 59.8 3.8 1.7 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein Ank_2 PF12796.7 EGG10799.1 - 1.8e-32 111.8 0.3 2.9e-13 50.2 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG10799.1 - 7.1e-22 77.5 1.6 4.3e-12 46.3 0.2 3.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG10799.1 - 1.1e-16 60.6 2.2 1e-05 25.7 0.2 5.2 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG10799.1 - 3.8e-15 54.5 0.4 0.00065 20.0 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EGG10799.1 - 2.9e-14 52.7 3.3 0.00014 22.2 0.1 4.1 3 0 0 3 3 3 3 Ankyrin repeat Aldolase_II PF00596.21 EGG10799.1 - 0.096 12.6 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain Mucin PF01456.17 EGG10799.1 - 0.23 11.4 4.0 0.44 10.5 4.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DIL PF01843.19 EGG10800.1 - 1.5e-26 92.7 4.4 4.6e-26 91.1 2.7 2.7 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 EGG10800.1 - 6.6e-13 49.1 0.0 3e-11 43.7 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG10800.1 - 4.1e-11 42.1 0.0 1.2e-06 28.3 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EGG10800.1 - 4.7e-10 39.8 0.4 2.9e-07 30.9 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG10800.1 - 2.7e-08 33.9 0.0 0.0015 18.7 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGG10800.1 - 7e-07 29.4 0.2 3.8e-05 23.9 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Got1 PF04178.12 EGG10801.1 - 1.1e-15 58.0 12.2 1.4e-15 57.7 12.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.6 EGG10801.1 - 3.3 7.7 13.4 3.5 7.6 2.6 2.5 2 0 0 2 2 2 0 YrhK-like protein zf-C3HC4_2 PF13923.6 EGG10803.1 - 4.2e-09 36.1 12.0 6.8e-09 35.4 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG10803.1 - 2.5e-08 33.6 8.6 3.9e-08 33.0 8.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG10803.1 - 5.1e-08 33.1 12.5 8.5e-08 32.4 12.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGG10803.1 - 2.3e-07 30.5 11.7 4.2e-07 29.7 11.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG10803.1 - 2.4e-07 30.6 7.6 2.4e-07 30.6 7.6 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGG10803.1 - 1.1e-06 28.6 14.0 2.2e-06 27.7 14.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGG10803.1 - 4.2e-05 23.4 11.4 7.2e-05 22.7 11.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 EGG10803.1 - 0.00076 19.6 6.7 0.0017 18.5 6.7 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 EGG10803.1 - 0.00092 19.3 0.5 0.0074 16.4 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-rbx1 PF12678.7 EGG10803.1 - 0.0033 17.7 13.2 0.023 15.0 13.2 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain BSP_II PF05432.11 EGG10803.1 - 0.008 15.9 2.9 0.011 15.4 2.9 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) zf-RING_4 PF14570.6 EGG10803.1 - 0.008 15.9 10.6 0.053 13.3 10.8 2.1 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EGG10803.1 - 0.051 13.4 5.3 0.14 12.0 5.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Exo_endo_phos_2 PF14529.6 EGG10803.1 - 0.061 13.2 2.4 0.14 12.1 2.4 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Prok-RING_4 PF14447.6 EGG10803.1 - 0.084 12.7 15.2 6.6 6.7 16.5 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGG10803.1 - 0.17 11.9 5.6 0.45 10.6 5.6 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EGG10803.1 - 0.27 11.1 5.7 0.43 10.5 5.7 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Glyoxal_oxid_N PF07250.11 EGG10805.1 - 6.2e-36 123.8 2.0 3.5e-33 114.8 1.7 3.5 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EGG10805.1 - 3.5e-25 88.1 0.1 7.8e-25 87.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) AcetylCoA_hydro PF02550.15 EGG10806.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain PrmA PF06325.13 EGG10807.1 - 2.9e-12 46.6 0.3 5.5e-12 45.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGG10807.1 - 4.8e-08 33.6 0.1 8.8e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG10807.1 - 2.1e-07 30.9 0.0 2.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG10807.1 - 5.2e-07 29.4 0.2 8e-07 28.8 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGG10807.1 - 6.7e-07 29.3 0.0 1.5e-06 28.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG10807.1 - 2.3e-05 25.0 0.0 3.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGG10807.1 - 0.00022 21.2 0.1 0.00039 20.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGG10807.1 - 0.0003 20.5 0.0 0.00047 19.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 EGG10807.1 - 0.00043 20.0 0.0 0.0017 18.0 0.1 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 FtsJ PF01728.19 EGG10807.1 - 0.0014 18.8 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 EGG10807.1 - 0.0016 19.1 0.0 0.0029 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGG10807.1 - 0.0017 18.4 0.0 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EGG10807.1 - 0.0059 16.5 0.0 0.0086 15.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 EGG10807.1 - 0.0084 15.9 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_9 PF08003.11 EGG10807.1 - 0.013 14.4 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.19 EGG10807.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 EGG10807.1 - 0.031 13.7 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.20 EGG10807.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase HEAT PF02985.22 EGG10808.1 - 1.7e-06 27.8 2.7 0.23 11.8 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 EGG10808.1 - 0.00043 20.6 0.9 13 6.2 0.0 6.0 5 1 0 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EGG10808.1 - 0.0097 16.5 0.0 4.1 8.1 0.0 4.0 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 EGG10808.1 - 0.037 14.1 0.1 0.45 10.6 0.0 3.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat ChAPs PF09295.10 EGG10809.1 - 5e-147 490.0 0.0 2e-145 484.8 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 EGG10809.1 - 7.1e-07 29.6 2.6 0.0028 18.1 0.9 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG10809.1 - 2.5e-05 24.0 2.6 1 9.6 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG10809.1 - 0.00029 20.8 2.6 4 7.9 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG10809.1 - 0.27 11.5 2.2 21 5.4 0.3 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EGG10809.1 - 0.32 11.9 9.3 9 7.4 0.2 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG10809.1 - 0.4 11.0 4.5 64 3.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGG10809.1 - 0.64 9.2 7.0 1.6 7.9 0.8 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat GLYCAM-1 PF05242.11 EGG10810.1 - 0.017 15.2 1.3 0.17 12.0 0.1 2.4 2 1 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Gluconate_2-dh3 PF13618.6 EGG10810.1 - 0.032 14.5 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 TIM21 PF08294.11 EGG10811.1 - 2.7e-05 24.1 0.0 0.00089 19.1 0.0 2.4 2 0 0 2 2 2 1 TIM21 DUF2362 PF10154.9 EGG10811.1 - 0.036 13.0 0.1 0.059 12.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) ArAE_2_N PF10337.9 EGG10812.1 - 5.5 5.9 6.3 12 4.8 6.3 1.5 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal CaKB PF03185.15 EGG10813.1 - 1.4 8.6 5.2 2.2 7.9 5.2 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Sec1 PF00995.23 EGG10815.1 - 3.3e-132 442.6 0.0 3.8e-132 442.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family O-FucT PF10250.9 EGG10816.1 - 5.3e-06 26.4 0.0 7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Cep57_CLD_2 PF14197.6 EGG10820.1 - 0.02 15.0 3.0 0.064 13.4 0.4 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Matrilin_ccoil PF10393.9 EGG10820.1 - 0.027 14.3 3.0 0.8 9.6 0.3 2.9 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.12 EGG10820.1 - 0.037 14.5 0.8 0.066 13.7 0.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DASH_Hsk3 PF08227.11 EGG10820.1 - 0.068 13.5 1.7 0.69 10.3 0.4 2.2 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Med9 PF07544.13 EGG10825.1 - 2.7e-07 30.6 0.7 6.3e-07 29.4 0.7 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 EGG10825.1 - 0.0099 16.1 1.3 0.016 15.5 1.3 1.3 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF148 PF02520.17 EGG10825.1 - 1.8 8.7 5.6 0.87 9.7 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF148 HIT PF01230.23 EGG10826.1 - 3.7e-15 56.4 2.2 7.9e-15 55.4 2.2 1.5 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGG10826.1 - 0.00056 20.4 3.6 0.0017 18.9 3.6 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3730 PF12530.8 EGG10826.1 - 0.017 14.7 0.8 0.029 13.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Acetyltransf_4 PF13420.7 EGG10827.1 - 0.018 15.2 1.2 4.4 7.4 0.1 2.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GD_N PF16030.5 EGG10827.1 - 0.071 13.4 0.1 14 6.0 0.0 2.9 3 0 0 3 3 3 0 Serine protease gd N-terminus GPR_Gpa2_C PF11970.8 EGG10827.1 - 0.12 12.5 0.0 23 5.1 0.0 2.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term FlaA PF04620.12 EGG10827.1 - 0.18 11.4 3.3 3.1 7.4 0.3 2.4 2 0 0 2 2 2 0 Flagellar filament outer layer protein Flaa RAP PF08373.10 EGG10828.1 - 0.35 11.0 2.7 0.54 10.4 0.9 2.3 2 0 0 2 2 2 0 RAP domain Ras PF00071.22 EGG10830.1 - 2.6e-40 137.7 0.0 8.4e-40 136.0 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG10830.1 - 7.8e-15 55.2 0.1 1.7e-14 54.1 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG10830.1 - 0.00025 20.6 0.0 0.0044 16.5 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGG10830.1 - 0.0013 18.6 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EGG10830.1 - 0.0017 18.4 0.0 0.0066 16.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGG10830.1 - 0.0094 15.4 0.0 0.067 12.6 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ACP_syn_III PF08545.10 EGG10830.1 - 0.033 14.0 0.0 0.86 9.5 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AAA_7 PF12775.7 EGG10830.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region IIGP PF05049.13 EGG10830.1 - 0.14 11.1 0.0 1.7 7.6 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Ras PF00071.22 EGG10831.1 - 1.6e-38 131.8 0.0 3.1e-38 130.9 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG10831.1 - 8.9e-11 42.1 0.0 1.7e-10 41.2 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG10831.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.5 2 0 0 2 2 2 0 ADP-ribosylation factor family CRAL_TRIO PF00650.20 EGG10832.1 - 1e-22 80.5 0.0 1.5e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGG10832.1 - 3.5e-06 27.1 0.3 7.4e-06 26.1 0.3 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TssN PF17555.2 EGG10833.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssN ODV-E18 PF10717.9 EGG10833.1 - 0.32 10.9 2.1 2.3 8.1 0.9 2.6 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Hexapep_2 PF14602.6 EGG10834.1 - 3.2e-06 26.8 2.9 0.0014 18.3 0.5 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EGG10834.1 - 1.2e-05 24.8 7.0 0.012 15.3 0.2 3.8 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Dus PF01207.17 EGG10836.1 - 1e-47 162.8 0.0 1.8e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) CxC5 PF18718.1 EGG10837.1 - 2.4e-31 108.2 8.4 3.9e-31 107.6 8.4 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG10837.1 - 8.7e-14 51.5 0.6 8.7e-14 51.5 0.6 2.2 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases FhuF_C PF11575.8 EGG10837.1 - 0.38 10.7 6.1 1.8 8.6 1.2 2.7 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain His_Phos_1 PF00300.22 EGG10838.1 - 7.5e-30 104.1 0.0 2.7e-29 102.2 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Aminotran_3 PF00202.21 EGG10839.1 - 3.7e-103 345.3 0.0 4.6e-103 345.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGG10839.1 - 0.18 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II tRNA-synt_2b PF00587.25 EGG10840.1 - 1.5e-33 116.2 0.0 2.2e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGG10840.1 - 6.1e-10 39.1 0.1 1.5e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain Oxidored_molyb PF00174.19 EGG10841.1 - 2.9e-56 189.8 0.0 6.3e-56 188.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGG10841.1 - 7.6e-49 165.3 0.3 1.4e-48 164.4 0.3 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 EGG10841.1 - 1.8e-30 105.2 0.0 3.4e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGG10841.1 - 4.1e-28 98.2 0.0 8.5e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EGG10841.1 - 7.3e-19 67.7 0.0 2.6e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EGG10841.1 - 5.9e-09 36.2 0.0 2.2e-07 31.1 0.0 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Atg14 PF10186.9 EGG10842.1 - 1.6e-11 43.9 7.4 2e-11 43.6 7.4 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 T4SS_CagC PF16943.5 EGG10843.1 - 0.018 15.2 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system AAA PF00004.29 EGG10844.1 - 1.1e-84 281.4 0.0 1.8e-42 144.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG10844.1 - 2.3e-22 78.5 0.4 4.8e-11 42.3 0.4 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 EGG10844.1 - 7.5e-12 45.4 1.2 4.5e-05 23.5 0.1 4.6 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGG10844.1 - 2.6e-11 43.5 0.0 0.00028 20.7 0.0 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGG10844.1 - 1.5e-09 38.4 2.0 0.00098 19.5 0.1 3.8 2 2 2 4 4 4 2 AAA ATPase domain TIP49 PF06068.13 EGG10844.1 - 3.8e-09 36.2 0.1 0.00036 19.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_2 PF07724.14 EGG10844.1 - 4.4e-09 36.7 0.0 0.00054 20.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EGG10844.1 - 3.4e-07 30.6 0.0 0.026 14.9 0.0 3.4 4 0 0 4 4 3 2 RNA helicase AAA_33 PF13671.6 EGG10844.1 - 5.4e-07 29.9 0.0 0.0075 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGG10844.1 - 3.1e-06 27.5 0.9 0.18 12.0 0.1 4.0 2 2 1 3 3 3 2 AAA domain AAA_18 PF13238.6 EGG10844.1 - 5.9e-06 26.9 0.1 0.034 14.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 EGG10844.1 - 6.7e-06 25.6 0.3 0.07 12.5 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGG10844.1 - 1.6e-05 24.9 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 EGG10844.1 - 3.3e-05 23.9 0.0 0.012 15.6 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 EGG10844.1 - 4e-05 23.3 1.3 0.23 11.0 0.1 4.1 2 2 2 4 4 4 1 AAA domain IstB_IS21 PF01695.17 EGG10844.1 - 0.00012 21.8 0.0 0.47 10.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_3 PF07726.11 EGG10844.1 - 0.00016 21.5 0.1 1.4 8.8 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EGG10844.1 - 0.00016 21.1 0.0 0.58 9.5 0.0 3.2 3 1 0 4 4 4 2 KaiC AAA_17 PF13207.6 EGG10844.1 - 0.00017 22.0 0.0 0.36 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EGG10844.1 - 0.00078 19.0 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 EGG10844.1 - 0.0018 18.3 0.1 1 9.4 0.0 2.7 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EGG10844.1 - 0.0031 17.2 0.0 3 7.5 0.0 3.6 2 2 0 2 2 2 1 Sigma-54 interaction domain Vps4_C PF09336.10 EGG10844.1 - 0.0033 17.4 0.4 1.7 8.7 0.0 3.1 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.6 EGG10844.1 - 0.0035 17.5 0.0 0.6 10.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 EGG10844.1 - 0.0039 17.5 0.6 3.9 7.7 0.4 2.7 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGG10844.1 - 0.0045 16.7 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 EGG10844.1 - 0.009 15.1 0.0 1.5 7.8 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 IPT PF01745.16 EGG10844.1 - 0.01 15.3 0.1 0.63 9.4 0.1 2.4 2 0 0 2 2 2 0 Isopentenyl transferase ABC_tran PF00005.27 EGG10844.1 - 0.012 16.1 0.4 5 7.6 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 EGG10844.1 - 0.034 13.9 0.1 2.5 7.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 EGG10844.1 - 0.052 13.0 0.6 1.8 8.0 0.2 2.5 2 0 0 2 2 2 0 PhoH-like protein Herpes_env PF01673.18 EGG10844.1 - 0.09 11.7 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein NACHT PF05729.12 EGG10844.1 - 0.1 12.5 0.3 7.1 6.5 0.1 3.1 3 0 0 3 3 3 0 NACHT domain SKI PF01202.22 EGG10844.1 - 0.12 12.5 0.1 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Zeta_toxin PF06414.12 EGG10844.1 - 0.14 11.4 0.1 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin PQQ_2 PF13360.6 EGG10845.1 - 1.3e-08 34.8 0.3 5.9e-05 22.8 0.0 3.0 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.21 EGG10845.1 - 0.0027 17.6 3.3 18 5.5 0.0 5.1 5 1 0 5 5 5 2 PQQ enzyme repeat EMC1_C PF07774.13 EGG10846.1 - 9.6e-30 103.9 0.0 1.1e-29 103.7 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal Sulphotransf PF09037.10 EGG10848.1 - 0.074 12.6 0.1 0.082 12.4 0.1 1.0 1 0 0 1 1 1 0 Stf0 sulphotransferase Exo_endo_phos PF03372.23 EGG10850.1 - 0.029 13.9 0.0 0.063 12.8 0.0 1.6 1 1 1 2 2 2 0 Endonuclease/Exonuclease/phosphatase family DUF5517 PF17639.2 EGG10853.1 - 0.041 14.2 0.3 0.1 12.9 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5517) UQ_con PF00179.26 EGG10855.1 - 7e-38 129.4 0.2 8.5e-38 129.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Aa_trans PF01490.18 EGG10856.1 - 2.6e-83 280.0 32.7 3.2e-83 279.7 32.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YpmT PF17431.2 EGG10856.1 - 1.4 9.0 4.3 0.74 9.9 0.9 2.3 2 0 0 2 2 2 0 Uncharacterized YmpT-like SR-25 PF10500.9 EGG10856.1 - 6.6 6.3 8.2 15 5.1 8.2 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Gp58 PF07902.11 EGG10857.1 - 0.012 13.9 4.2 0.014 13.7 4.2 1.1 1 0 0 1 1 1 0 gp58-like protein TraG-D_C PF12696.7 EGG10857.1 - 0.14 12.1 3.1 0.23 11.5 3.1 1.3 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG DUF4094 PF13334.6 EGG10857.1 - 8.8 6.8 9.4 3.4 8.2 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) RNase_J_C PF17770.1 EGG10858.1 - 0.11 13.6 1.4 12 7.0 0.0 2.6 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain DUF702 PF05142.12 EGG10859.1 - 2.3 8.7 4.5 1.4 9.4 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) PDCD7 PF16021.5 EGG10860.1 - 0.0021 17.2 3.9 0.0028 16.8 3.9 1.2 1 0 0 1 1 1 1 Programmed cell death protein 7 Hox9_act PF04617.13 EGG10860.1 - 0.13 13.0 5.5 0.15 12.8 5.5 1.1 1 0 0 1 1 1 0 Hox9 activation region FAM176 PF14851.6 EGG10860.1 - 1.4 8.6 12.0 0.22 11.2 7.0 1.9 1 1 1 2 2 2 0 FAM176 family Presenilin PF01080.17 EGG10860.1 - 3.4 6.3 8.2 3.9 6.2 8.2 1.1 1 0 0 1 1 1 0 Presenilin Glyco_transf_20 PF00982.21 EGG10861.1 - 1.3e-182 607.7 0.0 1.5e-182 607.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 EGG10861.1 - 0.21 11.1 0.5 2.4 7.6 0.1 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 Glyco_hydro_71 PF03659.14 EGG10863.1 - 1.8e-87 293.6 0.4 2.3e-87 293.2 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 YbjQ_1 PF01906.17 EGG10864.1 - 2.4e-07 31.3 0.1 2.4e-07 31.3 0.1 3.1 2 1 0 2 2 2 1 Putative heavy-metal-binding PKHD_C PF18331.1 EGG10864.1 - 0.051 13.7 0.2 0.13 12.3 0.2 1.7 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain WD40 PF00400.32 EGG10865.1 - 1.7e-16 60.2 7.6 0.0067 17.3 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG10865.1 - 3.6e-10 40.0 0.2 1.9e-05 24.9 0.0 4.0 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG10865.1 - 0.0002 21.3 0.4 0.25 11.2 0.0 2.9 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A MetallophosC PF16370.5 EGG10865.1 - 0.024 14.9 0.7 0.065 13.5 0.7 1.8 1 1 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase WD40_like PF17005.5 EGG10865.1 - 0.049 13.0 0.0 0.37 10.1 0.0 2.3 3 0 0 3 3 3 0 WD40-like domain DUF438 PF04282.13 EGG10866.1 - 0.21 11.6 1.0 0.35 10.9 0.4 1.7 2 1 0 2 2 2 0 Family of unknown function (DUF438) NUC205 PF08168.11 EGG10869.1 - 0.3 10.6 1.1 0.49 9.9 0.0 1.9 2 0 0 2 2 2 0 NUC205 domain APOBEC_C PF05240.14 EGG10870.1 - 0.0043 17.0 0.0 0.039 13.9 0.3 2.1 2 0 0 2 2 2 1 APOBEC-like C-terminal domain DHR10 PF18595.1 EGG10870.1 - 0.096 12.7 0.5 1.9 8.6 0.0 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 EGG10874.1 - 0.0067 16.5 0.6 0.0098 15.9 0.6 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLZ PF16526.5 EGG10874.1 - 0.018 15.4 0.5 1.4 9.3 0.1 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1796 PF08795.10 EGG10874.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.3 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) TMEM174 PF15029.6 EGG10876.1 - 0.11 12.3 1.0 0.15 11.7 1.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 174 PspB PF06667.12 EGG10880.1 - 0.16 12.0 0.8 0.49 10.5 0.8 1.8 1 0 0 1 1 1 0 Phage shock protein B Glyco_hydro_125 PF06824.11 EGG10880.1 - 0.38 9.6 2.7 14 4.4 0.0 2.8 3 0 0 3 3 3 0 Metal-independent alpha-mannosidase (GH125) SPA PF08616.10 EGG10882.1 - 7.4e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis GGACT PF06094.12 EGG10883.1 - 1.2e-12 48.5 0.0 3.3e-12 47.1 0.0 1.7 1 1 1 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like MBOAT_2 PF13813.6 EGG10885.1 - 4.8e-13 49.2 3.3 4.8e-13 49.2 3.3 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.6 EGG10886.1 - 4.1e-16 59.0 3.5 6.1e-16 58.5 3.5 1.3 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family adh_short_C2 PF13561.6 EGG10887.1 - 6.3e-53 179.7 1.5 8.4e-53 179.3 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG10887.1 - 8.4e-41 139.6 1.9 1.2e-40 139.0 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG10887.1 - 9.5e-10 38.7 1.2 1.6e-09 37.9 1.2 1.3 1 0 0 1 1 1 1 KR domain DsbB PF02600.16 EGG10887.1 - 0.061 13.7 0.0 0.59 10.5 0.0 2.1 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB Prenyltrans PF00432.21 EGG10888.1 - 2.4e-21 75.2 16.9 6.5e-06 25.8 0.1 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Ank_2 PF12796.7 EGG10889.1 - 0.00093 19.7 0.0 0.0023 18.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG10889.1 - 0.014 15.7 0.0 0.072 13.4 0.0 2.0 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG10889.1 - 0.019 15.4 0.0 4.3 8.2 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeat Transthyretin PF00576.21 EGG10890.1 - 3.7e-32 111.3 0.0 4.1e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Cohesin PF00963.18 EGG10890.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.5 1 1 0 1 1 1 0 Cohesin domain Spt20 PF12090.8 EGG10891.1 - 0.042 13.5 0.5 0.05 13.2 0.5 1.1 1 0 0 1 1 1 0 Spt20 family RNA_pol_Rpc4 PF05132.14 EGG10891.1 - 0.32 11.4 4.8 0.5 10.8 4.8 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Hid1 PF12722.7 EGG10891.1 - 0.83 7.7 4.0 0.82 7.7 4.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dsh_C PF12316.8 EGG10891.1 - 1 9.8 5.1 1.3 9.4 5.1 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal YdfA_immunity PF12127.8 EGG10891.1 - 4.8 6.1 10.2 6.2 5.8 10.2 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial RLI PF04068.15 EGG10892.1 - 7.2 6.5 6.9 5.1 7.0 0.8 2.4 2 0 0 2 2 2 0 Possible Fer4-like domain in RNase L inhibitor, RLI RhoGEF PF00621.20 EGG10893.1 - 1.6e-11 44.8 0.8 1.6e-11 44.8 0.8 2.8 2 0 0 2 2 2 1 RhoGEF domain Glyco_trans_1_3 PF13528.6 EGG10896.1 - 0.017 14.4 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Glyco_transf_4 PF13439.6 EGG10896.1 - 0.054 13.5 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 RabGAP-TBC PF00566.18 EGG10898.1 - 1.8e-39 135.6 0.1 2.8e-39 135.0 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.18 EGG10899.1 - 2.9e-44 151.3 0.3 4.7e-44 150.6 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CmcI PF04989.12 EGG10901.1 - 0.022 14.4 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Cephalosporin hydroxylase ProRS-C_1 PF09180.11 EGG10903.1 - 3.4e-23 81.6 2.0 6.9e-23 80.6 2.0 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 EGG10903.1 - 2.5e-17 62.8 0.0 8.4e-17 61.1 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGG10903.1 - 1.2e-15 57.9 0.0 2.9e-15 56.7 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Phage_coat PF09063.10 EGG10903.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Phage PP7 coat protein Prok_Ub PF14454.6 EGG10903.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic Ubiquitin ORC6 PF05460.13 EGG10905.1 - 0.045 13.0 4.2 0.066 12.5 4.2 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pox_Ag35 PF03286.14 EGG10905.1 - 0.42 10.4 7.4 0.78 9.5 7.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Phage_holin_2_1 PF04971.12 EGG10907.1 - 0.094 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage P21 holin S DegS PF05384.11 EGG10907.1 - 0.65 9.5 7.6 0.2 11.2 1.0 3.0 3 0 0 3 3 3 0 Sensor protein DegS Syntaxin-6_N PF09177.11 EGG10907.1 - 8.8 7.0 8.2 14 6.3 0.1 3.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Vps55 PF04133.14 EGG10909.1 - 5.4e-40 136.0 7.6 6e-40 135.9 7.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 PEPcase PF00311.17 EGG10910.1 - 2.6 6.0 4.3 4 5.4 4.3 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Gpr1_Fun34_YaaH PF01184.19 EGG10911.1 - 3.8e-53 180.2 20.0 1.3e-52 178.4 20.0 1.7 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2244 PF10003.9 EGG10911.1 - 3.7 7.2 5.8 7.2 6.3 5.8 1.5 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) RNase_PH PF01138.21 EGG10912.1 - 1.9e-18 67.3 0.0 3.2e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGG10912.1 - 1.4e-09 37.9 0.0 2.9e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Peroxin-3 PF04882.12 EGG10913.1 - 1.6 7.6 5.9 1.7 7.5 5.9 1.2 1 0 0 1 1 1 0 Peroxin-3 Coilin_N PF15862.5 EGG10913.1 - 3.7 7.3 8.8 0.35 10.7 3.0 2.1 1 1 1 2 2 2 0 Coilin N-terminus LZ_Tnp_IS66 PF13007.7 EGG10913.1 - 6.7 7.6 12.7 9 7.2 2.4 2.9 2 1 0 2 2 2 0 Transposase C of IS166 homeodomain OST3_OST6 PF04756.13 EGG10914.1 - 6.8e-92 307.9 0.0 7.9e-92 307.7 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family PRCC PF10253.9 EGG10915.1 - 1.4e-19 71.8 29.0 1.1e-16 62.2 29.0 3.2 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting DUF4600 PF15372.6 EGG10915.1 - 0.24 11.9 1.8 0.31 11.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) EVI2A PF05399.11 EGG10919.1 - 0.079 12.5 3.3 0.13 11.8 3.3 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Menin PF05053.13 EGG10919.1 - 9.6 4.4 12.1 12 4.2 12.1 1.0 1 0 0 1 1 1 0 Menin API5 PF05918.11 EGG10920.1 - 0.21 10.3 1.4 0.23 10.3 1.4 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CxC1 PF18802.1 EGG10921.1 - 8.2e-34 115.9 0.3 1.8e-33 114.8 0.3 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG10921.1 - 1e-06 28.9 0.2 2e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG10921.1 - 0.064 13.1 0.2 0.2 11.5 0.1 1.9 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases Spc110_C PF18520.1 EGG10921.1 - 0.075 12.7 1.5 12 5.6 0.1 3.1 3 0 0 3 3 3 0 Spindle pole body component 110 C-terminal domain HI0933_like PF03486.14 EGG10922.1 - 0.11 11.2 0.1 1.9 7.1 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Fasciclin PF02469.22 EGG10923.1 - 8e-23 81.1 0.9 1.5e-12 47.9 0.0 4.9 4 1 0 4 4 4 4 Fasciclin domain HPIP PF15226.6 EGG10923.1 - 0.053 13.9 0.1 0.053 13.9 0.1 2.0 2 0 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family DUF872 PF05915.12 EGG10924.1 - 0.035 14.3 0.6 0.085 13.0 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Questin_oxidase PF14027.6 EGG10926.1 - 3.2e-86 290.0 0.3 5.9e-86 289.1 0.3 1.4 1 0 0 1 1 1 1 Questin oxidase-like Alanine_zipper PF11839.8 EGG10926.1 - 0.067 13.6 0.2 0.067 13.6 0.2 2.0 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein DnaJ PF00226.31 EGG10927.1 - 9.6e-20 70.5 0.1 1.9e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain MBOAT_2 PF13813.6 EGG10928.1 - 2.3e-14 53.4 1.4 2.3e-14 53.4 1.4 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family VPS9 PF02204.18 EGG10929.1 - 0.00027 21.1 0.1 0.00037 20.7 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DMA PF03474.14 EGG10929.1 - 0.0038 16.8 0.2 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 DMRTA motif Aldo_ket_red PF00248.21 EGG10932.1 - 6.2e-78 262.0 0.0 7.3e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ExbD PF02472.16 EGG10932.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR CxC1 PF18802.1 EGG10933.1 - 1.1e-33 115.5 0.3 2.3e-33 114.5 0.3 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG10933.1 - 1.3e-06 28.6 0.2 2.5e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGG10933.1 - 0.087 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase Spc110_C PF18520.1 EGG10933.1 - 0.13 11.9 1.6 14 5.4 0.1 3.0 3 0 0 3 3 3 0 Spindle pole body component 110 C-terminal domain CxC3 PF18804.1 EGG10933.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases HI0933_like PF03486.14 EGG10934.1 - 0.12 11.1 0.1 2 7.0 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Alpha_kinase PF02816.18 EGG10936.1 - 5.9e-09 36.3 0.0 8.3e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Pex14_N PF04695.13 EGG10937.1 - 0.0042 17.7 3.0 0.0086 16.7 3.0 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PNISR PF15996.5 EGG10937.1 - 0.37 11.0 8.7 0.7 10.1 8.7 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Presenilin PF01080.17 EGG10937.1 - 3 6.5 4.9 4.2 6.0 4.9 1.2 1 0 0 1 1 1 0 Presenilin Tubulin PF00091.25 EGG10938.1 - 3.6e-65 219.9 0.0 4.8e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGG10938.1 - 3e-49 166.4 0.0 4.7e-49 165.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGG10938.1 - 0.00041 20.1 0.0 0.00079 19.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF2985 PF11204.8 EGG10939.1 - 1.8e-26 92.1 4.2 3.8e-26 91.0 4.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) DUF2207 PF09972.9 EGG10939.1 - 0.13 11.0 0.4 1.2 7.8 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Sensor PF13796.6 EGG10939.1 - 0.15 12.1 3.1 0.2 11.7 0.2 2.1 2 0 0 2 2 2 0 Putative sensor DUF4349 PF14257.6 EGG10940.1 - 0.023 14.1 3.3 1.4 8.4 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Sec10 PF07393.11 EGG10940.1 - 0.042 12.3 4.4 0.053 11.9 4.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 RasGAP PF00616.19 EGG10940.1 - 0.043 13.5 0.7 0.068 12.9 0.7 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF2247 PF10004.9 EGG10940.1 - 0.061 13.1 0.1 0.099 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) ABC_tran_CTD PF16326.5 EGG10940.1 - 0.063 13.5 6.8 0.27 11.5 2.6 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 EGG10940.1 - 0.095 12.5 4.4 4.5 7.1 0.1 2.5 2 1 0 2 2 2 0 Septum formation initiator ATG16 PF08614.11 EGG10940.1 - 0.13 12.5 11.1 0.15 12.2 8.3 2.2 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) End3 PF12761.7 EGG10940.1 - 0.36 11.0 6.2 0.25 11.5 2.7 2.2 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Lebercilin PF15619.6 EGG10940.1 - 0.48 10.1 11.2 0.97 9.1 0.2 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2203 PF09969.9 EGG10940.1 - 0.8 10.4 5.3 5.5 7.7 2.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TPR_MLP1_2 PF07926.12 EGG10940.1 - 0.9 9.6 8.2 0.33 11.0 3.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Uso1_p115_C PF04871.13 EGG10940.1 - 1.2 9.5 7.6 0.28 11.5 1.7 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4140 PF13600.6 EGG10940.1 - 1.2 9.6 5.0 1.6 9.2 1.4 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cep57_MT_bd PF06657.13 EGG10940.1 - 1.7 9.2 11.3 0.92 10.0 3.2 3.2 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ADIP PF11559.8 EGG10940.1 - 1.9 8.6 12.1 0.32 11.1 3.9 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 EGG10940.1 - 2.1 8.9 10.9 1.9 9.0 3.0 3.0 2 1 1 3 3 3 0 Cell division protein ZapB DUF3123 PF11321.8 EGG10940.1 - 3.2 8.5 5.5 2.8 8.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Ax_dynein_light PF10211.9 EGG10940.1 - 3.8 7.4 8.9 0.44 10.5 2.8 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain DUF1640 PF07798.11 EGG10940.1 - 6.5 6.8 10.6 15 5.6 10.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Spc24 PF08286.11 EGG10940.1 - 8.4 6.7 7.0 7.4 6.9 3.1 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Pyr_redox_2 PF07992.14 EGG10941.1 - 2.2e-09 37.0 0.0 6.2e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGG10941.1 - 3e-06 26.6 0.0 0.00014 21.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGG10941.1 - 4.3e-06 26.8 0.2 7.8e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGG10941.1 - 0.00059 19.2 0.0 0.0039 16.5 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGG10941.1 - 0.073 11.8 0.3 0.91 8.1 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EGG10941.1 - 0.14 11.3 0.2 0.36 10.0 0.2 1.6 1 1 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EGG10941.1 - 0.17 10.9 0.5 0.59 9.1 0.7 1.7 2 0 0 2 2 2 0 FAD binding domain Alpha_kinase PF02816.18 EGG10943.1 - 7.4e-11 42.5 1.2 1.1e-10 42.0 1.2 1.3 1 0 0 1 1 1 1 Alpha-kinase family Lsr2 PF11774.8 EGG10945.1 - 8.4 6.6 15.0 0.026 14.7 2.3 3.3 2 0 0 2 2 2 0 Lsr2 PHD PF00628.29 EGG10947.1 - 2.1e-07 30.7 11.0 4.2e-07 29.8 11.0 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 EGG10947.1 - 0.046 13.7 5.4 0.11 12.5 5.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-CW PF07496.15 EGG10947.1 - 0.44 10.6 5.0 1.1 9.4 5.0 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger PI3K_C2 PF00792.24 EGG10951.1 - 0.043 13.7 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 E1_DerP2_DerF2 PF02221.15 EGG10955.1 - 2.5e-26 92.7 0.0 3.3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 ML domain Acyltransferase PF01553.21 EGG10956.1 - 9.1e-22 77.1 0.0 1.3e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase E1_DerP2_DerF2 PF02221.15 EGG10957.1 - 1.5e-25 90.1 0.0 2.1e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 ML domain DUF4739 PF15893.5 EGG10957.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4739) zf-RING_2 PF13639.6 EGG10958.1 - 4.2e-10 39.8 8.5 1.3e-09 38.2 8.5 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGG10958.1 - 3.2e-05 23.6 9.7 3.2e-05 23.6 9.7 2.2 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 EGG10958.1 - 0.0014 18.8 4.7 0.0029 17.7 3.9 2.0 2 0 0 2 2 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 EGG10958.1 - 0.034 14.4 9.5 0.42 10.9 9.5 2.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGG10958.1 - 0.038 13.9 8.5 0.088 12.8 8.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG10958.1 - 0.045 13.8 7.5 0.049 13.7 3.9 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-HC5HC2H PF13771.6 EGG10958.1 - 0.047 13.9 4.9 0.73 10.1 5.6 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain Ub-RnfH PF03658.14 EGG10958.1 - 0.094 13.1 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 RnfH family Ubiquitin zf-ANAPC11 PF12861.7 EGG10958.1 - 0.14 12.2 4.9 0.54 10.3 4.9 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EGG10958.1 - 0.68 9.9 9.1 2.2 8.2 9.1 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG10958.1 - 0.69 9.8 8.4 4.3 7.3 5.1 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EGG10958.1 - 0.85 9.8 7.9 2.6 8.2 7.9 1.9 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 EGG10958.1 - 1.5 9.1 6.8 7.1 7.0 6.8 2.2 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 EGG10958.1 - 2.9 7.8 7.3 12 5.8 7.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NUDIX_2 PF13869.6 EGG10959.1 - 2.7e-83 278.2 0.0 3.1e-83 278.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF4028 PF13220.6 EGG10959.1 - 0.15 11.8 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) Bromodomain PF00439.25 EGG10960.1 - 7.3e-20 70.8 0.0 1.5e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 EGG10960.1 - 1.6e-12 47.2 0.1 3.4e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Bromodomain associated PC-Esterase PF13839.6 EGG10963.1 - 0.0024 17.7 0.4 0.016 15.0 0.0 2.3 2 1 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p LOR PF04525.12 EGG10968.1 - 0.046 13.3 0.2 0.061 12.9 0.2 1.3 1 1 0 1 1 1 0 LURP-one-related Sugar_tr PF00083.24 EGG10976.1 - 1.5e-88 297.7 19.7 1.8e-88 297.4 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG10976.1 - 8.2e-24 84.2 39.0 2.9e-18 65.9 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGG10976.1 - 0.12 10.7 10.6 0.96 7.7 2.2 3.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Reticulon PF02453.17 EGG10976.1 - 0.21 11.5 4.8 0.49 10.3 0.2 2.9 2 0 0 2 2 2 0 Reticulon DUF3792 PF12670.7 EGG10976.1 - 0.24 11.6 18.3 0.11 12.6 2.6 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) UbiA PF01040.18 EGG10977.1 - 3e-25 89.0 0.4 3.2e-25 88.9 0.4 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Cu-oxidase_3 PF07732.15 EGG10979.1 - 7e-35 119.6 2.8 7e-35 119.6 2.8 4.6 7 0 0 7 7 7 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG10979.1 - 1e-30 106.3 7.1 1.7e-23 82.9 0.7 3.7 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGG10979.1 - 1.7e-18 67.2 0.5 5.1e-16 59.2 0.0 2.9 2 1 0 2 2 2 2 Multicopper oxidase PAPA-1 PF04795.12 EGG10982.1 - 0.19 12.5 8.3 0.24 12.2 8.3 1.1 1 0 0 1 1 1 0 PAPA-1-like conserved region Endomucin PF07010.12 EGG10983.1 - 0.12 12.4 12.9 0.15 12.0 12.9 1.1 1 0 0 1 1 1 0 Endomucin DUF4636 PF15468.6 EGG10983.1 - 6.2 6.5 10.0 0.88 9.2 5.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) RR_TM4-6 PF06459.12 EGG10983.1 - 6.7 6.5 7.8 8.7 6.1 7.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SMN PF06003.12 EGG10984.1 - 1.3e-08 34.4 10.0 1.7e-08 34.0 10.0 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Tudor_3 PF18115.1 EGG10984.1 - 0.00092 19.0 0.1 0.0017 18.1 0.1 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 EGG10984.1 - 0.0051 16.6 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain PWWP PF00855.17 EGG10984.1 - 0.0077 16.6 0.9 0.043 14.2 0.9 2.3 1 1 0 1 1 1 1 PWWP domain TUDOR PF00567.24 EGG10984.1 - 0.014 15.4 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Tudor domain DUF4537 PF15057.6 EGG10984.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4537) RP-C_C PF11800.8 EGG10984.1 - 0.13 12.4 9.4 0.038 14.1 1.0 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region Tudor_2 PF18104.1 EGG10984.1 - 0.13 12.0 0.1 0.33 10.7 0.1 1.6 1 1 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain CCDC53 PF10152.9 EGG10984.1 - 0.32 11.4 8.6 1.4 9.3 2.1 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CPSF100_C PF13299.6 EGG10984.1 - 0.39 10.9 10.1 1.6 8.8 1.2 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Eapp_C PF10238.9 EGG10984.1 - 0.52 10.4 6.9 2.9 8.0 2.5 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein RNA_pol_Rpc4 PF05132.14 EGG10984.1 - 0.69 10.3 13.6 2.2 8.7 3.2 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Striatin PF08232.12 EGG10984.1 - 1 10.0 12.5 2.5 8.7 2.0 2.1 2 0 0 2 2 2 0 Striatin family XRCC4 PF06632.12 EGG10984.1 - 1.3 7.8 14.3 1.4 7.7 3.5 2.1 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PcfK PF14058.6 EGG10984.1 - 1.7 8.9 14.4 0.19 12.0 5.3 2.2 2 0 0 2 2 2 0 PcfK-like protein RPN2_C PF18004.1 EGG10984.1 - 2.3 8.1 16.1 1.4 8.8 0.3 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain PDCD2_C PF04194.13 EGG10984.1 - 2.7 8.0 12.5 3.8 7.5 6.5 2.2 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain CFIA_Pcf11 PF11526.8 EGG10984.1 - 2.8 8.5 15.7 5.1 7.6 3.5 2.4 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 MRNIP PF15749.5 EGG10984.1 - 3.4 8.4 15.7 0.23 12.2 4.3 2.3 2 0 0 2 2 2 0 MRN-interacting protein DUF3362 PF11842.8 EGG10984.1 - 4.5 7.6 11.3 4.3 7.6 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3362) UPF0565 PF10561.9 EGG10984.1 - 4.8 6.3 6.7 1.5 7.9 0.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 BSMAP PF12280.8 EGG10984.1 - 7.6 6.7 8.2 2.3 8.4 2.6 2.0 2 0 0 2 2 2 0 Brain specific membrane anchored protein RR_TM4-6 PF06459.12 EGG10984.1 - 7.7 6.3 15.7 3.7 7.3 6.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 EGG10984.1 - 8.3 6.1 7.1 6.8 6.4 2.2 2.0 2 0 0 2 2 2 0 Connexin ANAPC1 PF12859.7 EGG10984.1 - 8.6 6.9 7.5 3.2 8.3 2.8 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 RMP PF14996.6 EGG10984.1 - 9 6.5 9.4 23 5.2 3.1 2.3 2 0 0 2 2 2 0 Retinal Maintenance AMP-binding PF00501.28 EGG10985.1 - 2.4e-16 59.4 0.0 9.4e-16 57.4 0.0 1.9 3 0 0 3 3 3 1 AMP-binding enzyme PP-binding PF00550.25 EGG10985.1 - 0.012 16.0 0.0 0.049 14.0 0.0 2.1 1 1 0 1 1 1 0 Phosphopantetheine attachment site WSD PF15613.6 EGG10986.1 - 8.4e-22 77.5 1.1 1.9e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Zip PF02535.22 EGG10986.1 - 3.1 6.9 6.5 4.1 6.5 6.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CENP-B_dimeris PF09026.10 EGG10987.1 - 2.1 8.8 8.0 5.2 7.5 1.0 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain LZ_Tnp_IS66 PF13007.7 EGG10987.1 - 6.1 7.7 7.2 3.4 8.5 2.0 2.7 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain DHR10 PF18595.1 EGG10988.1 - 3e-08 33.7 8.5 4.7e-08 33.1 8.5 1.4 1 1 0 1 1 1 1 Designed helical repeat protein 10 domain CorA PF01544.18 EGG10988.1 - 0.0045 16.3 0.6 0.0067 15.8 0.6 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CENP-H PF05837.12 EGG10988.1 - 0.015 15.7 0.9 0.015 15.7 0.9 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMCO5 PF14992.6 EGG10988.1 - 0.039 13.5 10.4 0.045 13.3 10.4 1.0 1 0 0 1 1 1 0 TMCO5 family Atg14 PF10186.9 EGG10988.1 - 2.1 7.3 8.7 2.3 7.2 8.7 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 IBN_N PF03810.19 EGG10990.1 - 3.9e-11 42.7 0.0 5.4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Aminotran_3 PF00202.21 EGG10991.1 - 3e-07 29.4 0.0 5.5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III DUF2433 PF10360.9 EGG10992.1 - 3.8e-45 153.0 0.0 8.5e-45 151.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Hydrolase_4 PF12146.8 EGG10993.1 - 5.2e-07 29.2 0.0 1.4e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIP PF03583.14 EGG10993.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase zf-RING_14 PF17978.1 EGG10995.1 - 0.003 18.0 2.5 0.0071 16.7 2.5 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 EGG10995.1 - 0.0058 16.5 12.6 0.36 10.7 7.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG10995.1 - 0.0079 16.0 1.2 0.0079 16.0 1.2 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGG10995.1 - 0.013 15.8 13.6 0.38 11.1 7.0 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 EGG10995.1 - 0.025 14.4 13.4 0.42 10.5 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-DBF PF07535.12 EGG10995.1 - 0.046 13.8 2.5 3.3 7.9 0.0 2.6 2 0 0 2 2 2 0 DBF zinc finger zf-RING_UBOX PF13445.6 EGG10995.1 - 0.24 11.5 10.3 1.3 9.1 5.1 2.6 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 EGG10995.1 - 1.4 9.0 12.1 3.1 7.8 5.1 2.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 EGG10995.1 - 1.8 8.4 17.6 0.29 11.0 7.8 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain TniQ PF06527.11 EGG10995.1 - 1.9 9.2 8.5 0.2 12.3 1.8 2.3 2 1 0 2 2 2 0 TniQ zf-RING_2 PF13639.6 EGG10996.1 - 2.1e-05 24.8 4.3 2.1e-05 24.8 4.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EGG10996.1 - 0.0088 15.8 2.7 0.0088 15.8 2.7 2.4 2 1 1 3 3 3 1 RING-like zinc finger FUSC PF04632.12 EGG10996.1 - 0.023 13.2 0.0 0.028 13.0 0.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-C3HC4_3 PF13920.6 EGG10996.1 - 0.038 13.9 2.0 0.038 13.9 2.0 1.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG10996.1 - 0.044 13.7 2.6 0.097 12.5 2.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Heme_oxygenase PF01126.20 EGG10996.1 - 0.054 13.3 0.0 0.12 12.1 0.1 1.5 2 0 0 2 2 2 0 Heme oxygenase zf-RING_4 PF14570.6 EGG10996.1 - 0.2 11.5 4.2 0.39 10.6 4.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EGG10996.1 - 0.36 10.8 7.9 0.1 12.6 4.8 1.8 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGG10996.1 - 1.5 8.7 6.9 4.5 7.2 6.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Asp-B-Hydro_N PF05279.11 EGG10998.1 - 0.068 13.2 2.0 0.099 12.7 2.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-RING_2 PF13639.6 EGG10999.1 - 1.6e-05 25.2 8.6 1.6e-05 25.2 8.6 1.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EGG10999.1 - 0.00094 18.9 2.6 0.0025 17.5 2.6 1.8 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 EGG10999.1 - 0.006 16.4 5.9 0.013 15.3 5.9 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGG10999.1 - 0.0084 16.0 9.7 0.015 15.3 9.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGG10999.1 - 0.011 15.5 6.5 0.019 14.8 6.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zw10 PF06248.13 EGG10999.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 zf-C3HC4_2 PF13923.6 EGG10999.1 - 0.79 9.6 8.0 1.6 8.6 8.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG10999.1 - 2 8.3 9.8 3.6 7.5 9.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Methyltransf_11 PF08241.12 EGG11000.1 - 4.5e-07 30.4 0.0 6.3e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG11000.1 - 1.2e-05 26.0 0.0 0.00029 21.5 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG11000.1 - 8.8e-05 23.2 0.8 0.001 19.8 0.1 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG11000.1 - 0.0018 18.1 0.0 0.01 15.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG11000.1 - 0.0068 16.3 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain zf-RING_2 PF13639.6 EGG11001.1 - 0.00071 19.9 6.8 0.001 19.3 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-LSD1 PF06943.12 EGG11001.1 - 1.9 8.4 5.8 1 9.3 0.5 2.4 2 0 0 2 2 2 0 LSD1 zinc finger zf-RING_5 PF14634.6 EGG11001.1 - 3.3 7.7 7.4 5.5 7.0 7.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Dsh_C PF12316.8 EGG11002.1 - 5.2 7.4 25.5 0.078 13.4 10.4 2.5 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal CTP_transf_like PF01467.26 EGG11003.1 - 4e-19 69.2 0.0 4.6e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase-like Zn_clus PF00172.18 EGG11004.1 - 5.7e-07 29.6 7.2 9.6e-07 28.8 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGG11004.1 - 0.00082 18.5 0.0 0.0026 16.8 0.0 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_2 PF13639.6 EGG11005.1 - 1.7e-05 25.1 5.6 1.7e-05 25.1 5.6 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EGG11005.1 - 0.00067 19.3 1.8 0.00067 19.3 1.8 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 EGG11005.1 - 0.049 13.6 3.3 0.11 12.4 3.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG11005.1 - 0.069 13.2 4.4 0.16 12.0 4.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger MRP-L51 PF10244.9 EGG11006.1 - 0.047 13.9 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit DNA_ligase_ZBD PF03119.16 EGG11007.1 - 0.042 13.9 0.9 7.3 6.7 0.4 3.1 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain SH3_1 PF00018.28 EGG11008.1 - 9.3e-13 47.6 0.1 1.7e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG11008.1 - 1.2e-11 44.1 0.0 1.8e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGG11008.1 - 6.8e-10 38.7 0.0 1.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain RRM_1 PF00076.22 EGG11009.1 - 3.8e-21 74.7 0.9 3.1e-13 49.3 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG11009.1 - 9.2e-05 22.5 0.0 0.016 15.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EGG11009.1 - 0.00014 21.7 0.0 0.001 19.0 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif GP120 PF00516.18 EGG11010.1 - 0.16 10.5 0.0 0.18 10.4 0.0 1.0 1 0 0 1 1 1 0 Envelope glycoprotein GP120 CD24 PF14984.6 EGG11010.1 - 0.19 12.0 3.6 0.32 11.3 3.6 1.3 1 0 0 1 1 1 0 CD24 protein CxC1 PF18802.1 EGG11011.1 - 3.2e-29 101.1 0.0 5.8e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG11011.1 - 7.5e-09 35.7 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG11011.1 - 0.0038 17.1 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGG11012.1 - 2.3e-22 79.7 0.1 3.5e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase SF3A2 PF16835.5 EGG11015.1 - 2.2e-39 133.7 0.0 3.3e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EGG11015.1 - 1.6e-06 28.3 2.7 2e-06 28.0 0.7 2.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EGG11015.1 - 0.00015 21.7 0.1 0.00022 21.2 0.1 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 EGG11015.1 - 0.1 12.2 1.0 0.18 11.4 1.0 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Cullin PF00888.22 EGG11016.1 - 1.3e-191 638.5 0.7 1.6e-191 638.2 0.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGG11016.1 - 5.7e-25 87.1 2.3 1.6e-24 85.7 0.4 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 EGG11016.1 - 0.0021 18.4 0.1 0.0092 16.3 0.1 2.2 1 0 0 1 1 1 1 Penicillinase repressor Yos9_DD PF17880.1 EGG11016.1 - 0.12 12.5 0.1 0.78 9.9 0.0 2.5 2 0 0 2 2 2 0 Yos9 dimerzation domain Methyltransf_25 PF13649.6 EGG11017.1 - 4.1e-13 49.9 0.0 1.2e-12 48.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG11017.1 - 1.2e-11 45.0 0.0 2.7e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG11017.1 - 3.9e-08 32.9 0.0 7.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGG11017.1 - 6.6e-08 32.5 0.0 2e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG11017.1 - 8.4e-08 32.2 0.0 1.9e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Filament PF00038.21 EGG11017.1 - 0.029 13.9 0.4 0.029 13.9 0.4 1.8 2 0 0 2 2 2 0 Intermediate filament protein MFS_2 PF13347.6 EGG11024.1 - 2.5e-06 26.3 21.4 5.8e-06 25.1 6.2 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein Nefa_Nip30_N PF10187.9 EGG11028.1 - 5.5e-31 107.0 18.3 6.1e-31 106.9 18.3 1.0 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Elongin_A PF06881.11 EGG11028.1 - 0.49 11.0 13.0 0.21 12.2 8.8 2.3 1 1 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Seipin PF06775.14 EGG11030.1 - 0.054 13.6 0.2 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Putative adipose-regulatory protein (Seipin) NPL4 PF05021.15 EGG11031.1 - 3.8e-108 361.5 0.0 5.7e-108 360.9 0.0 1.3 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EGG11031.1 - 1.6e-65 219.7 0.1 2.6e-65 219.0 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EGG11031.1 - 1.5e-05 25.4 0.0 2.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RanBP PF00641.18 EGG11031.1 - 3.9 6.9 7.4 0.089 12.1 0.6 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Pectinesterase PF01095.19 EGG11032.1 - 2.6e-35 121.6 0.1 3e-35 121.4 0.1 1.0 1 0 0 1 1 1 1 Pectinesterase CCDC-167 PF15188.6 EGG11035.1 - 0.0028 17.9 0.3 0.0055 17.0 0.3 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Ntox28 PF15605.6 EGG11035.1 - 0.054 13.7 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial toxin 28 Phytochelatin PF05023.14 EGG11036.1 - 1.6e-88 295.4 0.0 1.9e-88 295.3 0.0 1.0 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 EGG11036.1 - 0.0012 19.4 0.0 1.3 9.6 0.0 2.4 2 0 0 2 2 2 2 Peptidase_C39 like family HTH_21 PF13276.6 EGG11037.1 - 0.0012 19.0 4.2 0.0033 17.5 1.3 2.7 3 0 0 3 3 3 1 HTH-like domain HTH_32 PF13565.6 EGG11037.1 - 0.0063 17.1 3.2 0.7 10.5 0.0 3.6 3 1 1 4 4 4 1 Homeodomain-like domain Clr5 PF14420.6 EGG11037.1 - 0.0088 16.2 0.0 7 7.0 0.0 2.6 2 0 0 2 2 2 2 Clr5 domain RecX PF02631.16 EGG11037.1 - 0.073 13.5 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RecX family DUF3613 PF12266.8 EGG11039.1 - 0.015 15.1 0.2 3.6 7.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3613) L27_1 PF09058.10 EGG11039.1 - 0.12 12.4 0.0 0.56 10.2 0.0 2.1 2 1 0 2 2 2 0 L27_1 DnaJ PF00226.31 EGG11040.1 - 8.2e-11 41.9 0.0 3.9e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 EGG11040.1 - 2.6e-07 31.1 0.8 0.016 15.7 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Septum_form PF13845.6 EGG11040.1 - 0.0071 15.9 0.0 0.034 13.7 0.0 2.0 1 1 1 2 2 2 1 Septum formation TPR_14 PF13428.6 EGG11040.1 - 0.02 15.7 1.4 91 4.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGG11040.1 - 0.043 14.5 2.0 0.59 10.8 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG11040.1 - 0.044 13.9 9.1 8 6.9 0.8 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGG11040.1 - 0.24 12.1 1.7 26 5.8 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGG11040.1 - 0.25 11.6 9.7 3.9 7.9 0.5 4.3 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG11040.1 - 0.27 11.5 11.6 4.4 7.6 0.2 4.0 3 2 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Drf_DAD PF06345.11 EGG11040.1 - 0.35 11.0 0.9 0.75 10.0 0.0 2.1 2 0 0 2 2 2 0 DRF Autoregulatory Domain TPR_12 PF13424.6 EGG11040.1 - 1.1 9.5 9.8 15 6.0 0.8 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG11040.1 - 2.4 9.0 7.4 1.7 9.4 0.1 3.8 4 1 1 5 5 4 0 Tetratricopeptide repeat DUF5079 PF16882.5 EGG11042.1 - 0.051 13.4 0.4 0.071 13.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5079) U3_assoc_6 PF08640.11 EGG11043.1 - 0.11 12.6 0.8 0.26 11.4 0.2 1.9 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 CCDC-167 PF15188.6 EGG11043.1 - 0.16 12.4 0.9 0.3 11.5 0.5 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Peptidase_M15_3 PF08291.11 EGG11045.1 - 0.0025 17.9 0.5 1.5 9.0 0.1 2.4 1 1 1 2 2 2 2 Peptidase M15 UPF0492 PF15744.5 EGG11045.1 - 0.011 15.0 10.2 0.013 14.8 10.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 zf-HC2 PF13490.6 EGG11045.1 - 0.016 15.5 0.7 8.4 6.7 0.0 3.0 3 1 0 3 3 3 0 Putative zinc-finger PYC_OADA PF02436.18 EGG11045.1 - 0.036 13.8 1.0 0.076 12.8 1.0 1.6 1 0 0 1 1 1 0 Conserved carboxylase domain YolD PF08863.10 EGG11045.1 - 0.15 12.1 14.3 0.28 11.3 1.2 2.9 2 1 1 3 3 3 0 YolD-like protein VitD-bind_III PF09164.10 EGG11045.1 - 0.26 11.3 0.9 2.9 7.9 0.1 2.6 2 1 0 2 2 2 0 Vitamin D binding protein, domain III YscJ_FliF_C PF08345.11 EGG11045.1 - 2 8.7 9.6 14 6.0 6.7 2.1 1 1 1 2 2 2 0 Flagellar M-ring protein C-terminal Toxin_YhaV PF11663.8 EGG11045.1 - 2 8.5 6.6 11 6.1 0.9 2.2 1 1 1 2 2 2 0 Toxin with endonuclease activity, of toxin-antitoxin system PRA-PH PF01503.17 EGG11045.1 - 2.5 8.6 4.8 38 4.8 0.0 3.0 3 0 0 3 3 3 0 Phosphoribosyl-ATP pyrophosphohydrolase Troponin PF00992.20 EGG11047.1 - 0.011 16.0 0.6 0.011 16.0 0.6 2.6 2 0 0 2 2 2 0 Troponin Prominin PF05478.11 EGG11047.1 - 0.031 12.3 0.8 0.048 11.6 0.8 1.3 1 0 0 1 1 1 0 Prominin DASH_Dad4 PF08650.10 EGG11047.1 - 0.086 12.8 3.8 2.1 8.4 1.2 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad4 DUF573 PF04504.14 EGG11047.1 - 0.18 12.5 1.5 2.8 8.7 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function, DUF573 AAA_13 PF13166.6 EGG11047.1 - 0.22 10.1 6.7 0.38 9.4 6.7 1.3 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 EGG11047.1 - 0.22 11.5 5.5 1.5 8.9 0.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DASH_Hsk3 PF08227.11 EGG11047.1 - 0.35 11.3 2.9 2.1 8.8 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Syntaxin-6_N PF09177.11 EGG11047.1 - 0.46 11.1 6.3 5.3 7.7 2.4 3.7 3 1 1 4 4 3 0 Syntaxin 6, N-terminal COG2 PF06148.11 EGG11047.1 - 0.56 10.3 7.4 0.7 10.0 1.6 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YtxH PF12732.7 EGG11047.1 - 0.68 10.5 2.8 10 6.7 0.9 2.8 1 1 1 2 2 2 0 YtxH-like protein NPV_P10 PF05531.12 EGG11047.1 - 0.73 10.3 6.0 6.2 7.4 1.4 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4795 PF16043.5 EGG11047.1 - 0.76 9.3 15.5 1.8 8.1 2.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) HSBP1 PF06825.12 EGG11047.1 - 0.86 9.5 9.3 7 6.6 0.0 4.7 5 0 0 5 5 5 0 Heat shock factor binding protein 1 Exonuc_VII_L PF02601.15 EGG11047.1 - 0.87 9.1 6.7 1.5 8.3 6.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 EGG11047.1 - 0.89 8.4 13.5 0.93 8.3 12.1 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 EGG11047.1 - 1.1 10.0 8.4 0.88 10.2 3.2 2.8 1 1 1 2 2 2 0 Initiation control protein YabA SKA1 PF07160.12 EGG11047.1 - 1.3 8.9 10.6 3.8 7.3 3.2 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 PIN_8 PF18476.1 EGG11047.1 - 2.2 8.1 6.5 3.8 7.3 5.7 1.6 1 1 0 1 1 1 0 PIN like domain LPP PF04728.13 EGG11047.1 - 3.3 8.2 4.9 50 4.4 0.1 3.6 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Fib_alpha PF08702.10 EGG11047.1 - 3.4 7.9 12.9 4.1 7.6 6.5 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family SHE3 PF17078.5 EGG11047.1 - 3.8 7.2 10.3 35 4.0 10.3 2.1 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 ZapB PF06005.12 EGG11047.1 - 5.7 7.5 14.1 10 6.6 7.3 2.5 1 1 1 2 2 2 0 Cell division protein ZapB FlxA PF14282.6 EGG11047.1 - 5.9 7.0 18.6 18 5.4 4.2 3.4 1 1 2 3 3 3 0 FlxA-like protein Syntaxin_2 PF14523.6 EGG11047.1 - 7 7.1 11.0 37 4.8 1.2 3.3 1 1 2 3 3 3 0 Syntaxin-like protein BST2 PF16716.5 EGG11048.1 - 0.1 13.2 0.1 0.25 12.0 0.0 1.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 LdpA_C PF12617.8 EGG11048.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 1 0 1 1 1 0 Iron-Sulfur binding protein C terminal MHCassoc_trimer PF08831.10 EGG11049.1 - 0.084 12.9 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Ceramidase PF05875.12 EGG11053.1 - 4.3e-84 282.0 10.2 4.9e-84 281.9 10.2 1.0 1 0 0 1 1 1 1 Ceramidase DUF2157 PF09925.9 EGG11053.1 - 0.003 17.4 0.9 0.006 16.4 0.9 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2157) TMEM192 PF14802.6 EGG11053.1 - 0.023 13.8 0.4 0.043 12.9 0.4 1.4 1 0 0 1 1 1 0 TMEM192 family ODV-E18 PF10717.9 EGG11053.1 - 0.15 11.9 0.3 0.29 11.0 0.3 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DPBB_1 PF03330.18 EGG11055.1 - 6.2e-06 26.4 0.1 1.4e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 Lytic transglycolase NICE-1 PF15845.5 EGG11055.1 - 0.05 14.4 1.5 0.05 14.4 1.5 1.9 1 1 0 1 1 1 0 Cysteine-rich C-terminal 1 family CDC45 PF02724.14 EGG11055.1 - 0.46 8.7 1.7 0.56 8.4 1.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGG11055.1 - 0.51 8.5 2.2 0.59 8.3 2.2 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 EGG11055.1 - 2.1 8.8 10.9 3.7 8.0 10.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Dicty_REP PF05086.12 EGG11055.1 - 3.8 5.4 5.0 0.71 7.8 0.0 1.8 1 1 1 2 2 2 0 Dictyostelium (Slime Mold) REP protein NOA36 PF06524.12 EGG11055.1 - 4.2 6.6 9.9 6.2 6.1 9.9 1.2 1 0 0 1 1 1 0 NOA36 protein SNARE_assoc PF09335.11 EGG11056.1 - 1.6e-14 54.4 2.4 2.3e-14 53.9 2.4 1.2 1 0 0 1 1 1 1 SNARE associated Golgi protein ARID PF01388.21 EGG11059.1 - 3.8e-13 49.9 0.0 3.8e-13 49.9 0.0 3.6 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain PP2C PF00481.21 EGG11060.1 - 3.6e-66 223.4 0.0 4.6e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PAC3 PF10178.9 EGG11060.1 - 0.017 15.3 0.0 0.15 12.3 0.0 2.3 1 1 0 1 1 1 0 Proteasome assembly chaperone 3 Peptidase_M14 PF00246.24 EGG11060.1 - 0.073 12.9 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Zinc carboxypeptidase DUF229 PF02995.17 EGG11060.1 - 0.18 10.4 0.0 8.2 4.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF229) NIR_SIR PF01077.22 EGG11061.1 - 5.6e-52 175.4 0.0 1.3e-48 164.5 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 EGG11061.1 - 5.5e-27 94.7 0.0 1e-26 93.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 EGG11061.1 - 3.6e-26 90.8 0.0 2.2e-13 49.8 0.0 3.0 2 1 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain DNA_RNApol_7kD PF03604.13 EGG11062.1 - 4.6e-14 51.8 9.7 6e-14 51.4 9.7 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.10 EGG11062.1 - 0.0034 17.1 2.3 0.006 16.3 2.3 1.4 1 0 0 1 1 1 1 A2L zinc ribbon domain zf-ISL3 PF14690.6 EGG11062.1 - 0.0067 17.1 3.0 0.019 15.6 0.6 2.1 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-trcl PF13451.6 EGG11062.1 - 1.2 9.1 6.8 3.3 7.7 0.1 2.2 1 1 1 2 2 2 0 Probable zinc-ribbon domain zf_UBZ PF18439.1 EGG11062.1 - 3.7 7.2 6.4 3 7.5 0.3 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger COX15-CtaA PF02628.15 EGG11063.1 - 2.1e-09 36.9 0.1 2.1e-09 36.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein SNAPc19 PF15497.6 EGG11064.1 - 0.035 14.6 0.1 0.062 13.8 0.1 1.4 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 ORC6 PF05460.13 EGG11064.1 - 0.043 13.1 3.1 0.059 12.6 3.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) eIF3_subunit PF08597.10 EGG11064.1 - 0.88 9.4 8.1 1.6 8.6 8.1 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit OmpH PF03938.14 EGG11067.1 - 8.6e-05 22.9 10.2 0.00011 22.5 10.2 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 EGG11067.1 - 0.0021 17.5 4.8 0.0026 17.2 4.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) EzrA PF06160.12 EGG11067.1 - 0.018 13.3 8.6 0.022 13.0 8.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA F-actin_cap_A PF01267.17 EGG11067.1 - 0.018 14.5 3.8 0.026 14.0 3.7 1.3 1 1 0 1 1 1 0 F-actin capping protein alpha subunit FapA PF03961.13 EGG11067.1 - 0.019 13.6 4.7 0.021 13.4 4.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A MADF_DNA_bdg PF10545.9 EGG11067.1 - 0.021 15.1 2.3 0.021 15.1 2.3 1.9 1 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3584 PF12128.8 EGG11067.1 - 0.026 12.1 9.7 0.029 11.9 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cep57_MT_bd PF06657.13 EGG11067.1 - 0.044 14.2 3.5 0.044 14.2 3.5 2.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Spc7 PF08317.11 EGG11067.1 - 0.045 12.6 10.3 0.059 12.2 10.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 EGG11067.1 - 0.058 13.5 1.7 0.058 13.5 1.7 2.0 2 1 0 2 2 2 0 bZIP transcription factor BLOC1_2 PF10046.9 EGG11067.1 - 0.084 13.2 7.9 0.18 12.1 2.6 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2115 PF09888.9 EGG11067.1 - 0.093 13.2 5.6 0.16 12.5 5.4 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) FlaC_arch PF05377.11 EGG11067.1 - 0.11 12.9 3.6 0.31 11.5 0.2 3.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.9 EGG11067.1 - 0.13 11.7 10.8 0.23 10.9 9.8 1.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 Lebercilin PF15619.6 EGG11067.1 - 0.18 11.4 11.5 0.2 11.3 3.5 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Snapin_Pallidin PF14712.6 EGG11067.1 - 0.24 11.8 4.8 0.35 11.3 3.7 1.9 1 1 1 2 2 2 0 Snapin/Pallidin TMPIT PF07851.13 EGG11067.1 - 0.26 10.5 7.7 0.35 10.1 7.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 EGG11067.1 - 0.29 11.4 9.2 0.79 10.0 8.7 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain KELK PF15796.5 EGG11067.1 - 0.5 10.8 12.3 0.3 11.6 8.7 2.2 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Phage_GP20 PF06810.11 EGG11067.1 - 0.52 10.1 12.2 1.2 8.9 6.5 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF3450 PF11932.8 EGG11067.1 - 0.54 9.5 7.1 0.31 10.3 5.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ADIP PF11559.8 EGG11067.1 - 0.82 9.7 10.3 2.3 8.3 9.3 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 EGG11067.1 - 0.83 9.5 6.6 0.49 10.2 3.7 2.1 1 1 1 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.8 EGG11067.1 - 0.91 9.8 9.7 0.83 9.9 5.4 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 EGG11067.1 - 1.1 9.7 6.3 4.3 7.8 3.2 2.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FliD_C PF07195.12 EGG11067.1 - 1.4 8.3 7.6 0.79 9.1 2.2 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Exonuc_VII_L PF02601.15 EGG11067.1 - 1.6 8.2 5.5 1.9 8.0 5.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 EGG11067.1 - 2.4 7.0 3.8 2.9 6.7 3.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Syntaxin_2 PF14523.6 EGG11067.1 - 4 7.9 9.6 2.9 8.3 5.3 2.2 1 1 0 2 2 2 0 Syntaxin-like protein GrpE PF01025.19 EGG11067.1 - 6.2 6.5 12.1 10 5.7 10.3 2.0 1 1 1 2 2 2 0 GrpE DUF4354 PF14263.6 EGG11070.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) DnaB_2 PF07261.11 EGG11073.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Replication initiation and membrane attachment AAA_24 PF13479.6 EGG11076.1 - 0.026 14.3 0.4 0.032 14.0 0.4 1.2 1 0 0 1 1 1 0 AAA domain DUF4460 PF14687.6 EGG11076.1 - 0.13 12.3 2.8 0.75 9.9 0.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4460) DUF2448 PF10476.9 EGG11076.1 - 0.16 11.9 0.1 0.18 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) LMBR1 PF04791.16 EGG11076.1 - 0.94 8.3 2.2 1.1 8.1 2.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2706 PF10913.8 EGG11077.1 - 0.82 9.6 2.5 2.6 8.0 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) Actin PF00022.19 EGG11078.1 - 1.3e-20 73.4 0.0 1.1e-13 50.6 0.0 2.0 2 0 0 2 2 2 2 Actin Glyco_hydro_12 PF01670.16 EGG11080.1 - 4e-13 49.8 1.0 5e-13 49.5 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 AATase PF07247.12 EGG11081.1 - 0.023 13.3 1.4 0.026 13.1 0.4 1.5 1 1 1 2 2 2 0 Alcohol acetyltransferase THUMP PF02926.17 EGG11082.1 - 3.4e-05 24.0 0.2 0.00013 22.1 0.0 2.1 1 1 1 2 2 2 1 THUMP domain DUF4835 PF16119.5 EGG11082.1 - 0.14 11.2 0.2 0.29 10.2 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4835) Glutaredoxin PF00462.24 EGG11083.1 - 7e-19 67.8 0.0 3.8e-18 65.4 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EGG11083.1 - 8.3e-10 38.6 0.0 2.4e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin SH3BGR PF04908.15 EGG11083.1 - 0.0018 18.4 0.0 0.0053 16.9 0.0 1.7 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein OST3_OST6 PF04756.13 EGG11083.1 - 0.0083 15.5 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 EGG11083.1 - 0.013 15.4 0.1 1.4 8.9 0.0 2.6 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 EGG11083.1 - 0.056 13.8 0.1 17 5.8 0.0 3.0 2 1 1 3 3 3 0 Thioredoxin-like bZIP_1 PF00170.21 EGG11084.1 - 0.011 15.8 1.1 0.022 14.8 1.1 1.5 1 0 0 1 1 1 0 bZIP transcription factor Tet_JBP PF12851.7 EGG11088.1 - 0.034 13.5 0.1 0.19 11.0 0.1 2.1 2 1 0 3 3 3 0 Oxygenase domain of the 2OGFeDO superfamily Troponin PF00992.20 EGG11089.1 - 0.0083 16.4 1.5 0.0083 16.4 1.5 2.9 2 2 0 2 2 2 1 Troponin DASH_Dad4 PF08650.10 EGG11089.1 - 0.02 14.9 3.7 0.79 9.7 0.8 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad4 AAA_13 PF13166.6 EGG11089.1 - 0.04 12.6 6.3 0.078 11.6 6.3 1.4 1 0 0 1 1 1 0 AAA domain SHE3 PF17078.5 EGG11089.1 - 0.072 12.8 9.7 1.3 8.7 9.7 2.3 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF573 PF04504.14 EGG11089.1 - 0.09 13.4 2.1 1.1 10.0 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function, DUF573 Prominin PF05478.11 EGG11089.1 - 0.091 10.7 3.3 0.12 10.3 3.3 1.3 1 0 0 1 1 1 0 Prominin MciZ PF13072.6 EGG11089.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ DASH_Hsk3 PF08227.11 EGG11089.1 - 0.11 12.8 2.2 2.2 8.7 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like COG2 PF06148.11 EGG11089.1 - 0.21 11.7 8.0 0.42 10.7 1.2 3.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YtxH PF12732.7 EGG11089.1 - 0.22 12.1 3.2 20 5.8 3.2 2.9 1 1 0 1 1 1 0 YtxH-like protein DUF1664 PF07889.12 EGG11089.1 - 0.32 11.1 7.7 0.83 9.7 1.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlxA PF14282.6 EGG11089.1 - 0.39 10.7 19.4 5.4 7.1 3.8 3.7 1 1 2 3 3 3 0 FlxA-like protein NPV_P10 PF05531.12 EGG11089.1 - 0.41 11.1 6.8 2.8 8.5 1.7 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4795 PF16043.5 EGG11089.1 - 0.45 10.1 16.6 0.86 9.2 2.6 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) SlyX PF04102.12 EGG11089.1 - 0.5 11.0 8.9 1.7 9.3 0.8 3.6 2 2 1 3 3 3 0 SlyX Syntaxin_2 PF14523.6 EGG11089.1 - 0.53 10.7 11.7 15 6.0 0.8 3.5 1 1 2 3 3 3 0 Syntaxin-like protein LPP PF04728.13 EGG11089.1 - 0.58 10.6 5.2 22 5.5 0.1 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper PIN_8 PF18476.1 EGG11089.1 - 0.94 9.3 7.2 1.7 8.5 6.4 1.7 1 1 0 1 1 1 0 PIN like domain COG5 PF10392.9 EGG11089.1 - 1 9.5 6.2 23 5.1 1.5 3.1 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Spore_III_AB PF09548.10 EGG11089.1 - 1.6 8.8 6.0 0.45 10.6 0.3 2.3 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Med9 PF07544.13 EGG11089.1 - 1.7 8.8 8.7 10 6.3 0.1 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 YabA PF06156.13 EGG11089.1 - 1.8 9.2 11.4 0.47 11.1 3.0 3.2 2 1 1 3 3 2 0 Initiation control protein YabA ZapB PF06005.12 EGG11089.1 - 1.9 9.0 14.8 6.3 7.3 7.6 2.6 1 1 1 2 2 2 0 Cell division protein ZapB Baculo_p24 PF05073.12 EGG11089.1 - 3.8 7.3 7.1 1.1 9.0 2.1 2.2 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Cauli_DNA-bind PF03310.13 EGG11089.1 - 5.3 7.1 9.7 4.5 7.4 3.3 3.5 2 1 2 4 4 4 0 Caulimovirus DNA-binding protein FH2 PF02181.23 EGG11089.1 - 6.1 5.8 11.5 7.7 5.5 4.0 2.6 1 1 1 3 3 3 0 Formin Homology 2 Domain SKA1 PF07160.12 EGG11089.1 - 7.9 6.3 16.5 1.4 8.7 3.1 2.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 APG6_N PF17675.1 EGG11089.1 - 9 6.8 14.5 20 5.7 9.6 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2570 PF10828.8 EGG11090.1 - 0.02 14.7 0.1 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DUF1195 PF06708.11 EGG11090.1 - 0.054 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Sad1_UNC PF07738.13 EGG11091.1 - 7.8e-31 106.8 0.0 1.2e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal WSC PF01822.19 EGG11093.1 - 0.054 13.7 5.6 0.15 12.3 5.6 1.8 1 0 0 1 1 1 0 WSC domain Acetyltransf_9 PF13527.7 EGG11094.1 - 0.017 15.2 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG11094.1 - 0.069 13.6 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG11094.1 - 0.18 12.0 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Macoilin PF09726.9 EGG11096.1 - 6.7e-05 21.7 21.0 7.7e-05 21.5 21.0 1.0 1 0 0 1 1 1 1 Macoilin family TFIIF_alpha PF05793.12 EGG11096.1 - 0.0028 16.3 36.5 0.0036 16.0 36.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LAP1C PF05609.12 EGG11096.1 - 0.041 13.0 14.2 0.048 12.8 14.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Plk4_PB1 PF18190.1 EGG11096.1 - 0.18 12.0 4.7 0.24 11.6 0.0 2.2 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 LRIF1 PF15741.5 EGG11096.1 - 0.21 10.1 24.2 0.26 9.8 24.2 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 TAF4 PF05236.14 EGG11096.1 - 0.25 11.0 21.7 0.33 10.7 21.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PNISR PF15996.5 EGG11096.1 - 0.57 10.4 23.8 0.81 9.9 23.8 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Miga PF10265.9 EGG11096.1 - 0.58 9.1 13.7 0.66 8.9 13.7 1.2 1 0 0 1 1 1 0 Mitoguardin Cwf_Cwc_15 PF04889.12 EGG11096.1 - 0.64 9.7 23.0 0.99 9.1 23.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_S64 PF08192.11 EGG11096.1 - 0.83 8.1 19.6 1 7.8 19.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 XRN_M PF17846.1 EGG11096.1 - 0.89 8.4 7.5 1.1 8.1 7.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain CobT PF06213.12 EGG11096.1 - 0.94 8.8 16.9 1.4 8.2 16.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1682 PF07946.14 EGG11096.1 - 1 8.5 16.7 1.5 8.0 16.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF2151 PF10221.9 EGG11096.1 - 1.1 7.7 13.2 1.4 7.5 13.2 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator UPF0524 PF15823.5 EGG11096.1 - 1.1 8.6 12.6 1.5 8.1 12.6 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 PI3K_1B_p101 PF10486.9 EGG11096.1 - 1.2 6.8 17.3 1.4 6.6 17.3 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Apt1 PF10351.9 EGG11096.1 - 1.4 7.6 21.4 1.8 7.3 21.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain GNT-I PF03071.15 EGG11096.1 - 2.1 7.0 6.6 3 6.5 6.6 1.1 1 0 0 1 1 1 0 GNT-I family DUF3340 PF11818.8 EGG11096.1 - 2.1 8.5 22.0 2.1 8.5 20.8 1.6 2 0 0 2 2 1 0 C-terminal domain of tail specific protease (DUF3340) MCU PF04678.13 EGG11096.1 - 2.5 8.2 7.3 4.1 7.5 7.3 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Ndc1_Nup PF09531.10 EGG11096.1 - 3 6.4 13.6 3.8 6.1 13.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 EGG11096.1 - 4.6 5.2 16.9 5.3 5.0 16.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PMSI1 PF15322.6 EGG11096.1 - 5.6 6.3 12.6 7.7 5.9 12.6 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative RabGAP-TBC PF00566.18 EGG11096.1 - 6.8 6.3 7.2 11 5.6 7.2 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain DUF4551 PF15087.6 EGG11096.1 - 7.3 5.3 17.0 8.8 5.0 17.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Zip PF02535.22 EGG11096.1 - 8.1 5.6 9.3 12 5.0 9.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Atrophin-1 PF03154.15 EGG11096.1 - 8.6 4.5 28.7 11 4.2 28.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family Laminin_II PF06009.12 EGG11097.1 - 0.022 14.8 4.0 1.9 8.5 0.5 2.4 1 1 1 2 2 2 0 Laminin Domain II IFT57 PF10498.9 EGG11097.1 - 0.075 12.0 4.4 0.15 11.0 4.4 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ADIP PF11559.8 EGG11097.1 - 0.11 12.6 9.0 0.059 13.5 6.2 1.9 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 EGG11097.1 - 0.15 12.6 4.9 0.13 12.7 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Rootletin PF15035.6 EGG11097.1 - 0.16 12.0 7.9 0.28 11.2 7.9 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.12 EGG11097.1 - 0.16 12.6 6.1 0.11 13.2 1.9 2.4 1 1 0 2 2 2 0 SlyX Phage_GP20 PF06810.11 EGG11097.1 - 0.25 11.1 3.2 0.61 9.9 3.2 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF4200 PF13863.6 EGG11097.1 - 0.45 10.9 5.2 0.95 9.9 5.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF1664 PF07889.12 EGG11097.1 - 0.64 10.1 5.9 0.74 9.9 4.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EGG11097.1 - 1.5 9.0 9.5 0.37 11.0 5.4 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 EGG11097.1 - 1.6 9.0 9.9 3.5 7.9 1.9 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Prominin PF05478.11 EGG11097.1 - 2.5 5.9 6.4 0.68 7.8 0.8 1.9 1 1 1 2 2 2 0 Prominin ATG16 PF08614.11 EGG11097.1 - 3.4 7.8 10.7 20 5.3 10.7 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 EGG11098.1 - 0.013 15.9 3.5 0.069 13.6 0.2 2.6 1 1 1 2 2 2 0 Cell division protein ZapB Prominin PF05478.11 EGG11098.1 - 0.03 12.3 0.2 0.038 12.0 0.2 1.1 1 0 0 1 1 1 0 Prominin CLZ PF16526.5 EGG11098.1 - 0.038 14.3 1.7 1.8 9.0 0.1 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Peptidase_C97 PF05903.14 EGG11100.1 - 4.5e-23 81.8 0.0 1.1e-14 54.6 0.0 2.2 2 0 0 2 2 2 2 PPPDE putative peptidase domain FAM199X PF15814.5 EGG11100.1 - 0.2 10.7 7.0 0.29 10.2 7.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X Holin_9 PF16936.5 EGG11101.1 - 0.032 14.4 1.2 0.059 13.5 1.2 1.4 1 0 0 1 1 1 0 Putative holin EPL1 PF10513.9 EGG11101.1 - 0.17 12.3 6.5 0.25 11.7 6.5 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Menin PF05053.13 EGG11101.1 - 3.3 6.0 14.3 4.8 5.4 14.3 1.2 1 0 0 1 1 1 0 Menin NPR3 PF03666.13 EGG11101.1 - 3.9 6.2 6.7 5.1 5.8 6.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 EGG11101.1 - 4 6.1 9.5 5.7 5.6 9.5 1.2 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 EGG11101.1 - 4.5 7.7 6.4 6.6 7.1 6.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Macoilin PF09726.9 EGG11101.1 - 4.7 5.6 7.2 5.7 5.4 7.2 1.0 1 0 0 1 1 1 0 Macoilin family Vac_ImportDeg PF09783.9 EGG11102.1 - 5.9e-29 101.0 3.6 6.3e-29 100.9 3.6 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF1442 PF07279.11 EGG11102.1 - 0.07 12.4 0.0 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1442) DNA_pol_B PF00136.21 EGG11103.1 - 1.1e-99 334.3 0.0 1.4e-99 333.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGG11103.1 - 7.9e-17 61.4 0.0 1.2e-08 34.4 0.0 2.8 2 1 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGG11103.1 - 4e-10 40.0 3.1 8.1e-10 39.0 3.1 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta SUIM_assoc PF16619.5 EGG11103.1 - 0.0043 17.1 1.1 0.0089 16.1 0.2 2.1 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 EGG11108.1 - 3.7e-43 147.8 0.0 4e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11108.1 - 1.7e-25 89.8 0.0 2.1e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG11108.1 - 5.7e-06 25.8 0.0 8.3e-06 25.3 0.0 1.2 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGG11108.1 - 7.4e-05 22.8 0.0 0.0029 17.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGG11108.1 - 0.00014 20.8 0.0 0.00016 20.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGG11108.1 - 0.0019 17.6 0.2 0.0025 17.2 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WH1 PF00568.23 EGG11108.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 WH1 domain DUF1679 PF07914.11 EGG11108.1 - 0.11 11.3 0.1 2.3 7.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) RIO1 PF01163.22 EGG11108.1 - 0.13 11.8 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Nop53 PF07767.11 EGG11109.1 - 0.096 12.1 4.9 0.13 11.6 4.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FAM176 PF14851.6 EGG11109.1 - 0.68 9.6 10.7 0.94 9.1 2.8 2.3 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 EGG11109.1 - 1.8 9.0 18.4 0.14 12.5 6.5 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RRN3 PF05327.11 EGG11109.1 - 2 6.9 7.8 2.6 6.5 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 WRNPLPNID PF15017.6 EGG11109.1 - 9.1 7.2 17.5 2 9.3 4.8 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Pro_isomerase PF00160.21 EGG11110.1 - 5.7e-36 124.2 0.0 1.1e-35 123.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EGG11110.1 - 1.8e-16 59.7 0.0 3.2e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3455 PF11937.8 EGG11111.1 - 4.1e-21 76.0 0.0 5.6e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Mitofilin PF09731.9 EGG11112.1 - 4.9e-105 352.7 19.3 4.4e-104 349.6 19.3 1.9 1 1 0 1 1 1 1 Mitochondrial inner membrane protein MCPVI PF02993.14 EGG11112.1 - 6.1 6.6 8.2 0.46 10.3 2.8 1.8 2 0 0 2 2 2 0 Minor capsid protein VI TCTP PF00838.17 EGG11112.1 - 7.8 6.8 6.5 1.8 8.9 0.9 2.4 2 0 0 2 2 2 0 Translationally controlled tumour protein bZIP_1 PF00170.21 EGG11113.1 - 6.6e-05 22.9 8.3 0.00011 22.2 8.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGG11113.1 - 0.0029 17.6 11.5 0.0048 17.0 11.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper DUF2397 PF09660.10 EGG11113.1 - 0.23 10.3 5.3 0.31 9.9 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Rad1 PF02144.16 EGG11114.1 - 2.7e-12 46.3 0.0 3e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 UPF0556 PF10572.9 EGG11116.1 - 0.12 11.9 0.1 0.17 11.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 FTHFS PF01268.19 EGG11118.1 - 1.8e-257 855.0 0.1 2.9e-257 854.3 0.1 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EGG11118.1 - 5.8e-65 217.5 1.1 1.2e-64 216.5 0.4 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EGG11118.1 - 1.1e-33 115.9 0.1 3.5e-33 114.3 0.2 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Helicase_C_4 PF13871.6 EGG11118.1 - 0.033 13.9 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue DUF1688 PF07958.11 EGG11120.1 - 5.8e-155 516.2 0.0 6.5e-155 516.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) FAD-SLDH PF12318.8 EGG11121.1 - 0.049 13.7 0.0 0.073 13.1 0.0 1.2 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Pro_isomerase PF00160.21 EGG11122.1 - 2e-46 158.2 0.1 3.1e-46 157.5 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 EGG11122.1 - 0.001 18.8 1.1 0.0059 16.4 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG11122.1 - 0.029 14.6 12.8 0.87 10.0 0.1 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG11122.1 - 0.051 13.7 4.9 5.6 7.3 0.7 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat YozE_SAM_like PF06855.12 EGG11122.1 - 0.13 12.5 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 YozE SAM-like fold SSURE PF11966.8 EGG11122.1 - 0.15 11.8 0.0 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Fibronectin-binding repeat zf-RING_2 PF13639.6 EGG11123.1 - 3.6e-07 30.4 4.3 7.8e-07 29.3 4.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGG11123.1 - 0.0007 19.5 2.7 0.0007 19.5 2.7 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGG11123.1 - 0.034 13.9 2.3 0.034 13.9 2.3 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 EGG11123.1 - 0.035 14.1 4.3 0.055 13.5 1.3 2.5 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.11 EGG11123.1 - 0.17 12.2 3.4 0.17 12.2 2.3 1.6 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 EGG11123.1 - 1.7 8.6 8.5 0.072 13.0 2.8 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) VWA_2 PF13519.6 EGG11124.1 - 7.6e-17 61.9 0.3 3.5e-16 59.8 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.20 EGG11124.1 - 2.5e-09 36.4 18.2 0.0026 17.5 1.5 4.0 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.14 EGG11124.1 - 0.00046 20.1 0.7 0.0014 18.5 0.1 1.9 2 0 0 2 2 2 1 Ssl1-like NqrM PF04400.13 EGG11125.1 - 0.18 11.6 0.1 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 (Na+)-NQR maturation NqrM MIS13 PF08202.11 EGG11129.1 - 0.021 14.1 0.2 0.049 12.9 0.1 1.6 2 0 0 2 2 2 0 Mis12-Mtw1 protein family RINGv PF12906.7 EGG11131.1 - 0.037 14.1 0.2 0.074 13.2 0.2 1.5 1 0 0 1 1 1 0 RING-variant domain DUF2236 PF09995.9 EGG11132.1 - 2.2e-07 31.3 0.0 3.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) zf-RING_2 PF13639.6 EGG11133.1 - 0.01 16.1 5.3 0.016 15.5 5.3 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_14 PF17978.1 EGG11133.1 - 0.014 15.8 1.3 0.024 15.0 1.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Cation_efflux PF01545.21 EGG11134.1 - 5.1e-22 78.6 2.6 6.3e-22 78.3 2.6 1.1 1 0 0 1 1 1 1 Cation efflux family Zn-C2H2_12 PF18112.1 EGG11135.1 - 0.11 13.0 0.1 0.25 11.9 0.1 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Abhydro_lipase PF04083.16 EGG11136.1 - 5e-15 54.8 0.1 9.7e-15 53.9 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGG11136.1 - 2.4e-07 30.7 0.8 5.5e-07 29.5 0.1 2.0 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG11136.1 - 6.2e-05 22.4 0.1 0.00031 20.1 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PBP_N PF17093.5 EGG11136.1 - 2.5 8.3 8.3 2.8 8.2 6.6 1.8 1 1 1 2 2 2 0 Penicillin-binding protein N-terminus BclA_C PF18573.1 EGG11138.1 - 0.088 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 BclA C-terminal domain zinc_ribbon_5 PF13719.6 EGG11138.1 - 0.098 12.4 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Ten1_2 PF15490.6 EGG11138.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit V-ATPase_G PF03179.15 EGG11146.1 - 0.01 16.4 0.5 0.019 15.5 0.5 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit PAM2 PF07145.15 EGG11146.1 - 0.25 11.1 1.2 0.48 10.2 1.2 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region PRP1_N PF06424.12 EGG11149.1 - 0.31 11.4 8.2 0.38 11.2 8.2 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal CDC45 PF02724.14 EGG11149.1 - 4.1 5.6 9.1 4.4 5.5 9.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Cyclin_N PF00134.23 EGG11150.1 - 7.4e-13 48.4 0.2 1.2e-12 47.7 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGG11150.1 - 5.3e-09 36.7 0.3 1.3e-08 35.4 0.3 1.7 1 1 0 1 1 1 1 Cyclin RVT_3 PF13456.6 EGG11151.1 - 2.6e-08 33.7 0.0 6.5e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like Abhydrolase_3 PF07859.13 EGG11153.1 - 2.4e-41 142.0 0.0 1.3e-32 113.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGG11153.1 - 3.1e-14 52.7 0.0 6.1e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EGG11153.1 - 0.0021 17.0 0.0 0.012 14.6 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family DUF913 PF06025.12 EGG11154.1 - 0.051 12.6 0.2 0.081 11.9 0.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RunxI PF08504.11 EGG11155.1 - 2.4 8.9 6.2 16 6.2 0.7 2.7 1 1 1 2 2 2 0 Runx inhibition domain RRM_1 PF00076.22 EGG11156.1 - 3.9e-09 36.2 0.9 0.00033 20.4 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG11156.1 - 9.3e-09 35.2 0.1 0.0021 18.0 0.1 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 EGG11156.1 - 0.00012 21.8 5.3 0.00022 21.0 5.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.11 EGG11156.1 - 0.0059 16.6 0.2 2.7 8.1 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Torus PF16131.5 EGG11156.1 - 0.12 13.1 0.3 0.39 11.4 0.3 1.8 1 0 0 1 1 1 0 Torus domain zf_CCCH_4 PF18345.1 EGG11156.1 - 1.3 9.2 7.8 2.4 8.3 7.8 1.5 1 0 0 1 1 1 0 Zinc finger domain GFD1 PF17331.2 EGG11156.1 - 2 8.7 10.8 3.7 7.9 10.8 1.4 1 0 0 1 1 1 0 GFD1 mRNA transport factor ELO PF01151.18 EGG11158.1 - 8.4e-28 97.6 3.7 9.6e-28 97.4 3.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ATP-synt_Eps PF04627.13 EGG11159.1 - 7.3e-19 67.5 3.0 1e-18 67.1 3.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Trigger_C PF05698.14 EGG11159.1 - 0.031 14.3 0.1 0.039 14.0 0.1 1.1 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus NAD_binding_6 PF08030.12 EGG11161.1 - 4e-35 121.2 0.0 1.4e-34 119.5 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGG11161.1 - 4.5e-21 75.0 0.1 1.1e-20 73.7 0.1 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EGG11161.1 - 7.2e-17 61.7 12.2 7.2e-17 61.7 12.2 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component PP2C PF00481.21 EGG11162.1 - 1.7e-36 126.2 0.0 5.1e-34 118.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Retrotran_gag_2 PF14223.6 EGG11163.1 - 0.0014 18.3 0.1 0.0023 17.6 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MpPF26 PF07666.11 EGG11166.1 - 0.14 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 ESSS PF10183.9 EGG11169.1 - 9e-09 35.5 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) YkyA PF10368.9 EGG11170.1 - 0.015 14.9 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Tmemb_cc2 PF10267.9 EGG11170.1 - 0.043 13.0 0.1 0.071 12.2 0.1 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Baculo_PEP_C PF04513.12 EGG11170.1 - 0.047 13.7 0.9 0.098 12.7 0.9 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PBP1_TM PF14812.6 EGG11172.1 - 0.018 15.4 1.3 0.018 15.4 1.3 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SATase_N PF06426.14 EGG11175.1 - 0.016 15.6 0.1 0.041 14.3 0.0 1.7 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal F-actin_cap_A PF01267.17 EGG11175.1 - 0.032 13.7 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 F-actin capping protein alpha subunit NA37 PF04245.13 EGG11175.1 - 0.094 12.2 0.6 0.13 11.7 0.6 1.1 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein GPP34 PF05719.11 EGG11175.1 - 0.1 12.6 2.4 0.17 11.9 2.4 1.5 1 1 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) TFCD_C PF12612.8 EGG11175.1 - 0.13 12.0 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DUF3919 PF13057.6 EGG11181.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) NPR1_interact PF15699.5 EGG11182.1 - 0.0034 18.0 0.7 1.2 9.8 0.1 2.9 3 0 0 3 3 3 2 NPR1 interacting PerC PF06069.11 EGG11182.1 - 0.0087 16.3 0.6 4.1 7.7 0.0 3.3 4 0 0 4 4 4 1 PerC transcriptional activator PTPS PF01242.19 EGG11182.1 - 0.021 14.8 0.0 6.2 6.8 0.0 3.2 2 1 1 3 3 3 0 6-pyruvoyl tetrahydropterin synthase Dynein_light PF01221.18 EGG11182.1 - 0.064 13.6 2.2 3.2 8.1 0.2 3.0 3 0 0 3 3 3 0 Dynein light chain type 1 mCpol PF18182.1 EGG11182.1 - 0.075 13.4 0.3 15 6.0 0.0 2.7 2 0 0 2 2 2 0 minimal CRISPR polymerase domain DUF3387 PF11867.8 EGG11182.1 - 0.076 12.4 3.4 1.2 8.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3387) Asp PF00026.23 EGG11183.1 - 2.2e-54 185.0 0.1 4.5e-31 108.4 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG11183.1 - 1.2e-10 41.9 0.2 1.7e-08 34.9 0.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal SMC_N PF02463.19 EGG11185.1 - 1.5e-67 227.3 0.0 6.1e-66 222.0 0.0 3.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGG11185.1 - 3.9e-21 75.5 0.1 1.1e-20 74.0 0.1 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EGG11185.1 - 1.7e-10 41.8 23.5 1.7e-10 41.8 23.5 5.5 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.6 EGG11185.1 - 4.7e-10 39.8 6.1 0.00012 22.0 0.5 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGG11185.1 - 0.00015 21.4 0.1 0.00046 19.9 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF16 PF01519.16 EGG11185.1 - 0.00026 21.4 3.1 0.00026 21.4 3.1 7.3 4 2 2 7 7 7 1 Protein of unknown function DUF16 Filament PF00038.21 EGG11185.1 - 0.0011 18.6 5.0 0.0011 18.6 5.0 5.7 3 2 3 6 6 6 2 Intermediate filament protein DUF4164 PF13747.6 EGG11185.1 - 0.0012 19.0 6.0 0.0012 19.0 6.0 6.9 5 3 1 6 6 5 2 Domain of unknown function (DUF4164) GvpK PF05121.12 EGG11185.1 - 0.0053 16.8 2.5 0.0053 16.8 2.5 4.6 5 0 0 5 5 5 1 Gas vesicle protein K AvrLm4-7 PF18661.1 EGG11185.1 - 0.029 15.4 1.2 0.11 13.5 1.2 2.0 1 0 0 1 1 1 0 Avirulence Effector AvrLm4-7 AAA_15 PF13175.6 EGG11185.1 - 0.09 12.5 45.3 0.43 10.2 21.8 4.1 2 2 0 2 2 2 0 AAA ATPase domain Baculo_VP39 PF04501.12 EGG11185.1 - 1 8.8 5.7 1.4 8.4 1.1 2.6 2 0 0 2 2 2 0 Baculovirus major capsid protein VP39 CBFD_NFYB_HMF PF00808.23 EGG11186.1 - 3.1e-14 53.0 0.4 5.1e-14 52.3 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGG11186.1 - 0.016 15.6 0.4 0.022 15.1 0.4 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 EGG11186.1 - 0.084 13.4 0.3 2.1 8.9 0.0 2.2 1 1 0 2 2 2 0 Transcription initiation factor TFIID subunit A Sugar_tr PF00083.24 EGG11192.1 - 6e-90 302.3 16.0 6.9e-90 302.1 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG11192.1 - 2.9e-23 82.4 21.4 2.9e-23 82.4 21.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGG11192.1 - 0.053 11.8 8.1 0.036 12.4 1.9 2.7 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SpoIIIAC PF06686.11 EGG11192.1 - 0.74 10.0 4.8 3.8 7.8 0.0 3.7 3 0 0 3 3 3 0 Stage III sporulation protein AC/AD protein family Redoxin PF08534.10 EGG11195.1 - 1.3e-17 63.9 0.0 1.5e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin DUF4407 PF14362.6 EGG11196.1 - 9.9 5.4 7.7 12 5.1 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PI3_PI4_kinase PF00454.27 EGG11197.1 - 2e-29 103.2 2.6 2.3e-29 103.0 0.1 2.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGG11197.1 - 4.7e-08 32.7 0.2 2.4e-07 30.4 0.1 2.0 1 1 1 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pik1 PF11522.8 EGG11197.1 - 7e-05 22.7 1.2 0.001 19.0 0.1 3.0 2 1 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 EGG11197.1 - 0.039 13.3 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DUF3482 PF11981.8 EGG11197.1 - 1.5 8.1 3.4 3.2 7.1 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF1269 PF06897.12 EGG11197.1 - 3.4 8.0 6.0 9.1 6.6 6.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) TRPM_tetra PF16519.5 EGG11200.1 - 0.035 14.2 0.2 0.23 11.6 0.1 2.2 2 0 0 2 2 2 0 Tetramerisation domain of TRPM ABC_tran_CTD PF16326.5 EGG11200.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.9 2 2 0 3 3 3 0 ABC transporter C-terminal domain RHH_1 PF01402.21 EGG11200.1 - 9.7 6.3 7.1 45 4.2 0.8 3.4 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family CcdB PF01845.17 EGG11201.1 - 0.19 12.0 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 CcdB protein p450 PF00067.22 EGG11203.1 - 3.1e-68 230.6 0.0 3.9e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Omp28 PF11551.8 EGG11203.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein Omp28 bZIP_1 PF00170.21 EGG11206.1 - 5.6e-07 29.6 10.5 1.3e-06 28.3 10.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor Taxilin PF09728.9 EGG11206.1 - 0.0066 15.7 5.5 0.012 14.8 5.5 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein bZIP_2 PF07716.15 EGG11206.1 - 0.012 15.7 10.8 0.025 14.6 10.8 1.6 1 0 0 1 1 1 0 Basic region leucine zipper ZapB PF06005.12 EGG11206.1 - 0.018 15.5 1.8 0.018 15.5 1.8 1.9 2 0 0 2 2 2 0 Cell division protein ZapB TSC22 PF01166.18 EGG11206.1 - 0.34 11.3 2.8 1.2 9.4 2.8 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family CENP-H PF05837.12 EGG11206.1 - 1.6 9.2 7.5 0.1 13.0 2.1 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Med4 PF10018.9 EGG11207.1 - 9.7e-15 54.8 0.7 9.7e-15 54.8 0.7 2.0 1 1 1 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 H-kinase_dim PF02895.14 EGG11207.1 - 0.0066 16.8 0.2 0.73 10.3 0.3 2.6 2 1 0 2 2 2 1 Signal transducing histidine kinase, homodimeric domain Gal-3-0_sulfotr PF06990.11 EGG11207.1 - 0.031 13.2 0.1 0.073 11.9 0.1 1.5 1 1 0 1 1 1 0 Galactose-3-O-sulfotransferase SOAR PF16533.5 EGG11207.1 - 0.047 13.7 0.5 0.12 12.4 0.5 1.6 1 0 0 1 1 1 0 STIM1 Orai1-activating region Nab2 PF11517.8 EGG11207.1 - 0.061 13.6 0.4 0.16 12.3 0.2 1.7 1 1 1 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) BAR_3_WASP_bdg PF10456.9 EGG11207.1 - 0.082 12.4 1.9 0.32 10.4 0.4 2.0 1 1 1 2 2 2 0 WASP-binding domain of Sorting nexin protein putAbiC PF16872.5 EGG11207.1 - 0.11 13.2 4.2 0.13 13.0 3.1 1.7 1 1 0 1 1 1 0 Putative phage abortive infection protein p450 PF00067.22 EGG11211.1 - 1.2e-10 40.8 0.0 2.5e-06 26.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Cytochrom_B561 PF03188.16 EGG11212.1 - 3.1e-14 53.3 5.2 3.1e-14 53.3 5.2 1.9 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 EGG11212.1 - 0.069 13.3 9.7 0.083 13.0 4.1 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF4079) TPD52 PF04201.15 EGG11212.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Tumour protein D52 family NAD_Gly3P_dh_N PF01210.23 EGG11215.1 - 0.04 13.9 0.8 11 6.0 0.1 3.1 1 1 2 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PhyH PF05721.13 EGG11216.1 - 1.5e-48 165.9 0.0 1.8e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF908 PF06012.12 EGG11217.1 - 0.051 13.0 0.2 0.051 13.0 0.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) GH131_N PF18271.1 EGG11219.1 - 7.9e-46 156.8 0.1 1.1e-45 156.4 0.1 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Glyco_transf_90 PF05686.12 EGG11221.1 - 4.3e-16 58.8 1.7 1.5e-15 57.0 0.6 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 90 Neur_chan_memb PF02932.16 EGG11221.1 - 0.07 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3134 PF11332.8 EGG11225.1 - 3.8 7.9 5.7 11 6.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) zf-H2C2_2 PF13465.6 EGG11226.1 - 1.9e-07 31.2 17.2 0.0013 19.0 4.4 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG11226.1 - 1.4e-06 28.7 11.8 0.0014 19.3 0.7 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGG11226.1 - 5.1e-06 26.6 19.7 2e-05 24.8 1.2 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGG11226.1 - 0.00023 21.1 3.7 0.00039 20.3 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EGG11226.1 - 0.0019 18.9 1.0 0.095 13.4 0.2 2.4 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 EGG11226.1 - 0.0035 17.7 0.2 0.0035 17.7 0.2 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Serglycin PF04360.12 EGG11226.1 - 0.025 14.5 0.2 0.066 13.2 0.2 1.6 1 0 0 1 1 1 0 Serglycin zf-Di19 PF05605.12 EGG11226.1 - 0.17 12.2 5.0 0.33 11.3 5.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 EGG11226.1 - 0.31 11.4 5.7 6 7.3 0.2 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 EGG11226.1 - 0.44 10.2 0.1 0.44 10.2 0.1 2.1 1 1 1 2 2 2 0 MYST family zinc finger domain zf-C2H2_jaz PF12171.8 EGG11226.1 - 0.68 10.3 0.0 0.68 10.3 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EGG11226.1 - 0.85 9.6 6.6 14 5.8 1.5 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type RAP1 PF07218.11 EGG11226.1 - 2.4 6.4 5.2 3.1 6.0 5.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apc15p PF05841.11 EGG11227.1 - 0.0013 19.6 0.5 0.0034 18.2 0.1 1.8 1 1 1 2 2 2 1 Apc15p protein Mem_trans PF03547.18 EGG11228.1 - 9.7e-15 53.8 4.1 6e-14 51.2 4.1 1.9 1 1 0 1 1 1 1 Membrane transport protein zf-H2C2_2 PF13465.6 EGG11229.1 - 1.4e-05 25.3 4.5 1.4e-05 25.3 4.5 2.0 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGG11229.1 - 0.00014 22.1 13.4 0.0013 19.0 6.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG11229.1 - 0.00059 20.5 12.0 0.00098 19.8 7.4 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGG11229.1 - 0.0098 15.6 3.7 0.016 14.9 3.7 1.3 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 EGG11229.1 - 0.019 14.9 4.9 0.33 11.0 1.8 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGG11229.1 - 0.13 12.6 4.7 0.46 10.8 1.5 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 EGG11229.1 - 0.2 10.1 1.7 0.19 10.2 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Ofd1_CTDD PF10637.9 EGG11230.1 - 9.5e-80 267.6 0.2 7e-73 245.1 0.1 2.7 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EGG11230.1 - 1.2e-30 106.0 0.0 7.3e-30 103.5 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EGG11230.1 - 2.1e-15 57.4 0.0 5.5e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily tRNA_synthFbeta PF17759.1 EGG11232.1 - 4.3e-50 170.1 0.0 5.8e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EGG11232.1 - 1.2e-26 92.7 0.1 1.6e-24 85.9 0.1 2.6 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EGG11232.1 - 9.2e-23 80.8 0.2 1.5e-22 80.1 0.2 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EGG11232.1 - 3.6e-19 68.8 0.0 5.3e-16 58.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 EGG11232.1 - 0.017 14.6 0.0 0.091 12.2 0.0 2.0 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) MipZ PF09140.11 EGG11232.1 - 0.093 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ Gpr1_Fun34_YaaH PF01184.19 EGG11233.1 - 1.6e-86 289.2 22.3 2e-86 288.9 22.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2244 PF10003.9 EGG11233.1 - 1 9.0 4.8 3.1 7.5 4.8 1.8 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) WD40 PF00400.32 EGG11234.1 - 3.2e-35 119.5 23.8 7.5e-06 26.6 0.7 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG11234.1 - 0.00046 20.4 0.4 0.85 10.0 0.1 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG11234.1 - 0.001 17.8 0.4 1.2 7.7 0.0 3.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Peptidase_C65 PF10275.9 EGG11235.1 - 0.014 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase C65 Otubain Bromo_TP_like PF17027.5 EGG11236.1 - 0.027 14.6 2.0 0.038 14.1 2.0 1.2 1 0 0 1 1 1 0 Histone-fold protein FBPase_glpX PF03320.13 EGG11236.1 - 0.027 13.4 0.1 0.031 13.1 0.1 1.1 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Hira PF07569.11 EGG11238.1 - 2.3e-27 96.2 2.6 4e-22 79.1 0.1 2.4 1 1 1 2 2 2 2 TUP1-like enhancer of split WD40 PF00400.32 EGG11238.1 - 1.5e-24 85.8 21.7 5.1e-05 24.0 1.4 9.2 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG11238.1 - 1.3e-11 44.6 1.0 0.45 10.8 0.1 7.2 4 2 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EGG11238.1 - 1.8e-07 30.8 0.1 1.8e-07 30.8 0.1 2.2 2 0 0 2 2 2 1 HIRA B motif TonB_2 PF13103.6 EGG11238.1 - 0.076 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 TonB C terminal Pox_Ag35 PF03286.14 EGG11240.1 - 0.011 15.5 8.9 0.011 15.5 8.9 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM104 PF15434.6 EGG11242.1 - 2.8 8.5 8.8 4.8 7.8 0.9 2.2 1 1 1 2 2 2 0 Family 104 Metallophos PF00149.28 EGG11243.1 - 7.7e-35 121.2 0.1 1.9e-34 119.9 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 EGG11243.1 - 0.2 11.4 1.2 2.8 7.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) 2-Hacid_dh_C PF02826.19 EGG11246.1 - 8.4e-51 171.9 0.0 2.3e-50 170.4 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGG11246.1 - 2.2e-29 101.8 0.0 2.7e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 EGG11246.1 - 0.0055 16.8 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 EGG11246.1 - 0.012 15.8 0.1 0.027 14.7 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ribosomal_60s PF00428.19 EGG11247.1 - 9.8e-28 96.6 5.8 1.2e-27 96.3 5.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein zf-RING_11 PF17123.5 EGG11249.1 - 4.6e-07 29.5 2.9 1.3e-06 28.1 2.9 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGG11249.1 - 1.7e-06 28.2 0.6 1.7e-06 28.2 0.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG11249.1 - 0.00049 20.1 0.8 0.0015 18.5 0.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_1 PF14446.6 EGG11249.1 - 0.026 14.4 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.6 EGG11249.1 - 0.05 13.5 0.4 0.05 13.5 0.4 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) WW PF00397.26 EGG11250.1 - 3e-09 36.8 0.0 6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 WW domain FAD_binding_4 PF01565.23 EGG11251.1 - 1.3e-25 89.7 0.2 2.2e-25 89.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGG11251.1 - 1.9e-11 43.9 2.5 4.3e-11 42.7 2.5 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EGG11251.1 - 0.0017 17.8 0.1 0.0031 17.0 0.1 1.4 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding MBOAT_2 PF13813.6 EGG11253.1 - 1e-14 54.5 2.3 3.3e-14 52.9 2.3 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Nramp PF01566.18 EGG11254.1 - 3.4e-89 299.3 12.0 3.4e-50 171.0 1.6 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein DUF4577 PF15145.6 EGG11254.1 - 0.22 11.5 1.5 3.6 7.6 0.4 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4577) DUF2976 PF11190.8 EGG11254.1 - 6.3 6.7 6.9 0.52 10.1 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) AA_kinase PF00696.28 EGG11255.1 - 3.2e-29 102.2 0.0 4.8e-27 95.1 0.0 2.2 2 0 0 2 2 2 2 Amino acid kinase family ACT PF01842.25 EGG11255.1 - 6.6e-11 41.8 0.2 3.7e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 EGG11255.1 - 2.1e-09 37.0 3.2 2.8e-07 30.2 0.3 2.4 2 0 0 2 2 2 2 ACT domain CSD PF00313.22 EGG11256.1 - 0.074 12.9 0.2 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain ADH_N PF08240.12 EGG11257.1 - 3.6e-33 113.7 2.5 7.4e-33 112.7 2.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGG11257.1 - 1.6e-16 60.4 0.0 3.2e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGG11257.1 - 1.1e-14 54.4 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGG11257.1 - 7.8e-08 33.4 0.0 1.3e-07 32.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 EGG11257.1 - 5.1e-06 26.0 0.1 8.4e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 EGG11257.1 - 0.008 16.6 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EGG11257.1 - 0.035 14.2 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EGG11257.1 - 0.036 12.8 0.3 0.051 12.3 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 EGG11257.1 - 0.045 14.0 0.1 0.096 12.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG11257.1 - 0.063 12.5 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 EGG11257.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 EGG11257.1 - 0.11 11.8 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG11257.1 - 0.14 12.7 0.1 1.4 9.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MBOAT_2 PF13813.6 EGG11258.1 - 4e-05 23.8 0.5 0.00018 21.7 0.5 2.1 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family Coatomer_E PF04733.14 EGG11259.1 - 2e-23 83.3 0.3 3.2e-23 82.6 0.3 1.2 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EGG11259.1 - 0.00044 20.7 0.7 1.7 9.3 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG11259.1 - 0.0052 17.5 0.2 13 6.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat PDDEXK_7 PF04411.12 EGG11259.1 - 0.11 12.4 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily TPR_2 PF07719.17 EGG11259.1 - 0.11 12.6 0.0 0.61 10.3 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.7 EGG11271.1 - 0.00012 21.9 0.3 0.00034 20.4 0.3 1.9 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EGG11271.1 - 0.00063 20.1 3.4 0.0093 16.4 0.7 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) F-box PF00646.33 EGG11271.1 - 0.0036 17.1 0.2 0.016 15.1 0.2 2.0 1 0 0 1 1 1 1 F-box domain IPK PF03770.16 EGG11272.1 - 2e-37 129.0 0.1 2.2e-37 128.8 0.1 1.0 1 0 0 1 1 1 1 Inositol polyphosphate kinase CxC1 PF18802.1 EGG11273.1 - 0.0023 18.1 0.1 0.0038 17.3 0.1 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases DUF2390 PF09523.10 EGG11273.1 - 0.18 12.1 6.5 0.35 11.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) KDZ PF18758.1 EGG11274.1 - 1.3e-47 162.3 0.0 2e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Mrr_N PF14338.6 EGG11274.1 - 0.05 13.7 0.1 0.72 10.0 0.1 2.7 3 0 0 3 3 3 0 Mrr N-terminal domain ACOX PF01756.19 EGG11275.1 - 6.1e-44 149.7 0.1 1.1e-43 148.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EGG11275.1 - 1.7e-26 93.2 1.9 3.1e-26 92.4 1.9 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EGG11275.1 - 3.1e-15 56.1 0.0 7.8e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGG11275.1 - 0.0032 17.7 5.1 0.0089 16.2 2.9 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain COPIIcoated_ERV PF07970.12 EGG11276.1 - 9.3e-38 130.3 0.2 1.4e-37 129.7 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGG11276.1 - 5.3e-26 90.8 0.0 9e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Nfu_N PF08712.11 EGG11278.1 - 1.3e-31 108.5 0.0 3.8e-31 107.0 0.0 1.8 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EGG11278.1 - 7.9e-26 90.0 0.1 1.3e-25 89.3 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain MFS_1 PF07690.16 EGG11280.1 - 5.1e-34 117.7 20.1 5.9e-32 110.9 23.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.18 EGG11280.1 - 0.0018 17.1 0.3 0.0018 17.1 0.3 2.0 2 0 0 2 2 2 1 Reduced folate carrier YtpI PF14007.6 EGG11280.1 - 0.0034 17.5 1.5 0.0034 17.5 1.5 3.8 4 0 0 4 4 4 1 YtpI-like protein NinB PF05772.12 EGG11280.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 NinB protein DUF1179 PF06678.11 EGG11281.1 - 0.36 10.8 4.3 0.33 11.0 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) bZIP_1 PF00170.21 EGG11282.1 - 1.7e-08 34.4 6.4 3.2e-08 33.5 6.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGG11282.1 - 1e-07 31.9 5.2 2.2e-07 30.9 5.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGG11282.1 - 0.033 14.7 2.8 0.033 14.7 2.8 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Rabaptin PF03528.15 EGG11282.1 - 0.048 12.4 1.6 0.087 11.5 1.6 1.3 1 0 0 1 1 1 0 Rabaptin CFIA_Pcf11 PF11526.8 EGG11282.1 - 0.3 11.6 0.1 0.3 11.6 0.1 3.0 3 1 0 3 3 3 0 Subunit of cleavage factor IA Pcf11 Nnf1 PF03980.14 EGG11282.1 - 3.1 8.2 7.9 0.4 11.1 2.3 2.4 2 1 0 2 2 2 0 Nnf1 Glyco_hydro_88 PF07470.13 EGG11283.1 - 1.1e-17 64.1 0.2 2.3e-17 63.1 0.1 1.5 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Glyco_hydro_88 PF07470.13 EGG11285.1 - 1.6e-13 50.5 0.0 1.9e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 LZ_Tnp_IS66 PF13007.7 EGG11286.1 - 0.012 16.3 0.1 0.017 15.9 0.1 1.3 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain DUF1326 PF07040.11 EGG11286.1 - 0.16 12.0 0.0 0.19 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) Retrotran_gag_2 PF14223.6 EGG11287.1 - 1.2e-05 25.0 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TonB_N PF16031.5 EGG11287.1 - 8.7 6.9 10.3 0.98 9.9 2.9 2.6 2 0 0 2 2 2 0 TonB polyproline region adh_short PF00106.25 EGG11288.1 - 8e-40 136.4 0.0 1.6e-39 135.4 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG11288.1 - 2.8e-26 92.5 0.0 5.5e-26 91.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG11288.1 - 2.8e-12 46.9 0.5 4.5e-10 39.7 0.5 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG11288.1 - 0.00079 19.0 0.1 0.0024 17.4 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGG11288.1 - 0.098 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain SKIP_SNW PF02731.15 EGG11289.1 - 5.4e-73 243.9 0.9 5.4e-73 243.9 0.9 2.3 2 0 0 2 2 2 1 SKIP/SNW domain Ribosomal_L37 PF08561.10 EGG11289.1 - 3.5 8.2 9.7 2.7 8.6 2.5 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Imm5 PF14423.6 EGG11295.1 - 0.0058 16.9 2.6 0.0085 16.3 2.6 1.2 1 0 0 1 1 1 1 Immunity protein Imm5 YceD PF02620.17 EGG11295.1 - 0.016 15.3 0.2 0.027 14.6 0.2 1.3 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD TFIIA PF03153.13 EGG11295.1 - 0.055 13.5 11.5 0.07 13.1 11.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_16 PF13191.6 EGG11295.1 - 0.46 10.8 4.6 0.72 10.2 4.6 1.3 1 0 0 1 1 1 0 AAA ATPase domain baeRF_family2 PF18844.1 EGG11295.1 - 2.6 8.1 18.5 0.15 12.1 0.4 2.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 DUF572 PF04502.13 EGG11295.1 - 2.9 7.5 6.8 3.7 7.1 6.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) bVLRF1 PF18826.1 EGG11299.1 - 1.5e-08 34.7 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor ABC_tran_CTD PF16326.5 EGG11301.1 - 0.044 14.0 2.3 0.11 12.8 0.0 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain BPD_transp_2 PF02653.16 EGG11302.1 - 0.023 13.9 3.9 0.046 12.9 3.9 1.5 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Glyco_hydr_116N PF12215.8 EGG11302.1 - 0.042 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Ribosomal_L17 PF01196.19 EGG11303.1 - 4.5e-30 104.4 0.8 1.2e-29 103.1 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L17 Fungal_KA1 PF16797.5 EGG11303.1 - 0.036 13.8 0.1 0.089 12.5 0.1 1.6 1 0 0 1 1 1 0 Fungal kinase associated-1 domain STG PF15809.5 EGG11303.1 - 0.045 13.8 0.1 0.13 12.3 0.1 1.7 2 0 0 2 2 2 0 Simian taste bud-specific gene product family SDA1 PF05285.12 EGG11304.1 - 4.1 6.7 24.2 7.4 5.9 24.2 1.4 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 EGG11304.1 - 4.9 7.0 16.3 0.45 10.5 8.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sporozoite_P67 PF05642.11 EGG11307.1 - 0.19 9.8 0.1 0.24 9.5 0.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen p450 PF00067.22 EGG11309.1 - 1.8e-51 175.4 0.0 2.5e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF746 PF05344.11 EGG11309.1 - 0.039 13.8 0.6 3.6 7.5 0.0 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF746) Beta_helix PF13229.6 EGG11310.1 - 2.9e-10 40.2 14.1 1.2e-09 38.2 14.1 2.0 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EGG11310.1 - 1.3e-05 24.6 2.3 0.0033 16.7 0.1 2.3 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Peptidase_M22 PF00814.25 EGG11311.1 - 2.8e-80 269.9 0.0 3.4e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family PA28_beta PF02252.18 EGG11312.1 - 9.2e-49 164.8 0.2 1e-48 164.7 0.2 1.0 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit F-box-like PF12937.7 EGG11313.1 - 0.0012 18.7 1.5 0.0012 18.7 1.5 2.4 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EGG11313.1 - 0.011 16.1 5.0 0.034 14.6 0.6 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Alpha_kinase PF02816.18 EGG11316.1 - 5.1e-14 52.8 0.0 9.2e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family HAP1_N PF04849.13 EGG11321.1 - 0.0027 16.9 0.5 0.0036 16.5 0.5 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region APG6_N PF17675.1 EGG11321.1 - 0.019 15.5 0.4 0.026 15.0 0.4 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region bZIP_1 PF00170.21 EGG11321.1 - 0.025 14.7 1.3 0.051 13.7 1.3 1.5 1 1 0 1 1 1 0 bZIP transcription factor Syntaxin PF00804.25 EGG11321.1 - 0.044 13.5 1.1 0.059 13.0 1.1 1.1 1 0 0 1 1 1 0 Syntaxin Mod_r PF07200.13 EGG11321.1 - 0.046 13.8 1.5 0.071 13.2 1.5 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein betaPIX_CC PF16523.5 EGG11321.1 - 0.082 12.7 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 betaPIX coiled coil ABC_tran_CTD PF16326.5 EGG11321.1 - 0.11 12.8 2.9 0.2 11.9 2.9 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain TMEM132D_C PF15706.5 EGG11323.1 - 0.06 13.1 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term ATP-synt_8 PF00895.20 EGG11323.1 - 0.22 12.0 0.1 0.34 11.4 0.1 1.3 1 0 0 1 1 1 0 ATP synthase protein 8 P_proprotein PF01483.20 EGG11324.1 - 0.12 12.4 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Proprotein convertase P-domain FAR1 PF03101.15 EGG11324.1 - 0.13 12.9 0.9 0.32 11.7 0.9 1.7 1 1 0 1 1 1 0 FAR1 DNA-binding domain Tom5 PF10642.9 EGG11325.1 - 0.082 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase NOA36 PF06524.12 EGG11325.1 - 1.2 8.4 10.3 1.5 8.0 10.3 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EGG11325.1 - 3.9 5.6 11.7 4.8 5.3 11.7 1.2 1 0 0 1 1 1 0 Nop14-like family Alpha_kinase PF02816.18 EGG11326.1 - 9.6e-17 61.7 0.0 1.5e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family HalX PF08663.10 EGG11328.1 - 0.00078 19.7 2.9 0.011 16.0 0.1 2.1 2 0 0 2 2 2 1 HalX domain FliJ PF02050.16 EGG11328.1 - 0.0093 16.2 0.4 0.012 15.8 0.4 1.4 1 1 0 1 1 1 1 Flagellar FliJ protein HAUS-augmin3 PF14932.6 EGG11328.1 - 0.017 14.7 1.2 0.022 14.3 1.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TolA_bind_tri PF16331.5 EGG11328.1 - 0.019 15.1 0.6 0.059 13.4 0.6 1.8 1 1 0 1 1 1 0 TolA binding protein trimerisation RasGAP_C PF03836.15 EGG11328.1 - 0.03 14.5 0.0 0.06 13.5 0.0 1.5 1 1 0 1 1 1 0 RasGAP C-terminus PilJ PF13675.6 EGG11328.1 - 0.03 14.4 0.3 0.06 13.4 0.1 1.5 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ATG16 PF08614.11 EGG11328.1 - 0.033 14.4 3.4 1.2 9.3 2.3 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 EGG11328.1 - 0.037 13.5 4.0 0.12 11.9 4.1 1.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 Uso1_p115_C PF04871.13 EGG11328.1 - 0.039 14.3 0.3 0.081 13.3 0.1 1.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DivIC PF04977.15 EGG11328.1 - 0.04 13.7 1.3 5.5 6.8 0.1 2.4 1 1 1 2 2 2 0 Septum formation initiator FapA PF03961.13 EGG11328.1 - 0.053 12.1 0.2 0.06 11.9 0.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 EGG11328.1 - 0.058 13.8 0.9 11 6.5 0.1 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TMCO5 PF14992.6 EGG11328.1 - 0.061 12.9 2.3 0.075 12.6 2.3 1.1 1 0 0 1 1 1 0 TMCO5 family Fib_alpha PF08702.10 EGG11328.1 - 0.11 12.7 0.3 0.47 10.6 0.1 1.8 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 EGG11328.1 - 0.13 12.8 1.7 4.4 7.8 0.2 2.3 1 1 1 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 EGG11328.1 - 0.15 12.7 2.1 1.8 9.2 0.1 2.5 1 1 1 2 2 2 0 SlyX DUF4200 PF13863.6 EGG11328.1 - 0.2 12.1 2.6 4 7.9 0.2 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) ABC_tran_CTD PF16326.5 EGG11328.1 - 0.24 11.7 5.4 3.3 8.0 0.1 2.6 3 0 0 3 3 3 0 ABC transporter C-terminal domain Trimer_CC PF08954.11 EGG11328.1 - 0.28 10.8 3.5 1.3 8.7 3.5 2.1 1 1 0 1 1 1 0 Trimerisation motif Lzipper-MIP1 PF14389.6 EGG11328.1 - 0.3 11.4 4.4 0.47 10.8 0.5 2.3 1 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 bZIP_2 PF07716.15 EGG11328.1 - 0.38 10.9 2.1 0.91 9.7 0.7 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Spc24 PF08286.11 EGG11328.1 - 0.46 10.7 2.7 3.3 8.0 2.7 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF5082 PF16888.5 EGG11328.1 - 0.57 10.5 2.4 25 5.1 0.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) MYO10_CC PF16735.5 EGG11328.1 - 0.76 9.9 5.9 0.46 10.6 2.7 2.2 2 1 0 2 2 2 0 Unconventional myosin-X coiled coil domain Uds1 PF15456.6 EGG11329.1 - 0.01 16.0 0.1 0.013 15.7 0.1 1.1 1 0 0 1 1 1 0 Up-regulated During Septation DUF3245 PF11595.8 EGG11330.1 - 0.031 14.7 3.5 0.082 13.4 3.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DUF4218 PF13960.6 EGG11330.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) BUD22 PF09073.10 EGG11330.1 - 0.32 10.3 11.3 0.51 9.6 11.3 1.2 1 0 0 1 1 1 0 BUD22 Sad1_UNC PF07738.13 EGG11333.1 - 1.9e-28 99.1 0.0 3.9e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF4201 PF13870.6 EGG11333.1 - 0.039 13.7 2.1 0.069 12.9 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.12 EGG11333.1 - 0.14 12.7 1.9 1.8 9.1 0.9 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 EGG11333.1 - 0.16 12.1 1.4 0.29 11.3 1.4 1.3 1 0 0 1 1 1 0 Tropomyosin like MerR-DNA-bind PF09278.11 EGG11333.1 - 0.17 12.4 2.5 46 4.7 0.0 3.4 3 0 0 3 3 3 0 MerR, DNA binding BLOC1_2 PF10046.9 EGG11333.1 - 0.35 11.2 8.0 0.6 10.4 5.3 2.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Snapin_Pallidin PF14712.6 EGG11333.1 - 1.6 9.2 6.3 2.1 8.8 2.2 2.5 3 0 0 3 3 3 0 Snapin/Pallidin TRPM_tetra PF16519.5 EGG11333.1 - 4.8 7.4 5.9 0.86 9.8 0.4 2.7 3 1 0 3 3 3 0 Tetramerisation domain of TRPM DivIC PF04977.15 EGG11333.1 - 5.1 6.9 7.2 5.8 6.8 0.2 3.1 2 1 1 3 3 3 0 Septum formation initiator ADIP PF11559.8 EGG11334.1 - 0.00032 20.8 19.6 0.18 11.8 5.7 3.2 1 1 2 3 3 3 3 Afadin- and alpha -actinin-Binding EzrA PF06160.12 EGG11334.1 - 0.0048 15.1 0.6 0.0048 15.1 0.6 2.1 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA DHR10 PF18595.1 EGG11334.1 - 0.0054 16.8 1.6 0.0054 16.8 1.6 3.0 1 1 2 3 3 3 1 Designed helical repeat protein 10 domain CCDC-167 PF15188.6 EGG11334.1 - 0.017 15.4 20.3 0.058 13.7 1.7 3.9 2 2 2 4 4 4 0 Coiled-coil domain-containing protein 167 HrpB7 PF09486.10 EGG11334.1 - 0.034 14.5 2.7 0.071 13.5 0.1 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF2730 PF10805.8 EGG11334.1 - 0.035 14.2 11.8 3 8.0 0.3 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) Fez1 PF06818.15 EGG11334.1 - 0.064 13.7 15.1 0.019 15.4 10.3 2.0 1 1 1 2 2 2 0 Fez1 FapA PF03961.13 EGG11334.1 - 0.12 11.0 14.5 0.063 11.9 0.7 2.4 1 1 1 2 2 2 0 Flagellar Assembly Protein A GM_CSF PF01109.17 EGG11334.1 - 0.13 12.4 1.1 9.1 6.5 0.1 2.7 2 1 1 3 3 3 0 Granulocyte-macrophage colony-stimulating factor RepA_C PF04796.12 EGG11334.1 - 0.16 11.9 1.2 0.22 11.5 0.3 1.6 2 0 0 2 2 2 0 Plasmid encoded RepA protein DUF724 PF05266.14 EGG11334.1 - 0.19 11.5 15.6 0.44 10.4 0.6 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF724) PCRF PF03462.18 EGG11334.1 - 0.23 11.3 8.2 0.14 12.0 0.3 2.2 2 0 0 2 2 2 0 PCRF domain FlaC_arch PF05377.11 EGG11334.1 - 0.29 11.6 14.1 12 6.3 0.1 4.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) IL5 PF02025.15 EGG11334.1 - 0.36 11.1 5.2 4 7.8 1.6 2.3 2 0 0 2 2 2 0 Interleukin 5 DUF1664 PF07889.12 EGG11334.1 - 0.44 10.6 17.2 0.64 10.1 0.4 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DNA_pol_delta_4 PF04081.13 EGG11334.1 - 1.2 9.4 6.1 0.41 11.0 2.8 1.8 2 0 0 2 2 2 0 DNA polymerase delta, subunit 4 DUF948 PF06103.11 EGG11334.1 - 1.4 9.2 5.5 7 7.0 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ORF6C PF10552.9 EGG11334.1 - 1.8 8.7 8.0 0.33 11.0 0.2 2.9 2 1 1 3 3 3 0 ORF6C domain Cluap1 PF10234.9 EGG11334.1 - 1.8 7.9 16.7 0.14 11.6 1.7 2.6 1 1 1 3 3 3 0 Clusterin-associated protein-1 DivIC PF04977.15 EGG11334.1 - 2.4 8.0 15.6 1.6 8.6 2.8 4.1 1 1 4 5 5 5 0 Septum formation initiator NPV_P10 PF05531.12 EGG11334.1 - 3 8.4 16.0 4.1 8.0 0.4 3.7 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Med10 PF09748.9 EGG11334.1 - 3 7.8 10.2 2e+02 1.9 10.2 3.1 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Fzo_mitofusin PF04799.13 EGG11334.1 - 5 6.7 16.9 8.4 5.9 5.6 3.3 1 1 1 3 3 3 0 fzo-like conserved region Jnk-SapK_ap_N PF09744.9 EGG11334.1 - 6.3 7.0 20.3 10 6.3 12.0 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ACCA PF03255.14 EGG11334.1 - 6.9 6.5 8.6 2.3 8.1 2.0 2.6 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2203 PF09969.9 EGG11334.1 - 7.1 7.4 7.0 8.7 7.1 0.4 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TSC22 PF01166.18 EGG11334.1 - 8 6.9 10.5 9.6 6.6 0.6 3.8 3 1 1 4 4 3 0 TSC-22/dip/bun family DASH_Dam1 PF08653.10 EGG11334.1 - 8.7 6.2 9.8 4.4 7.2 1.4 3.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 PRD PF00874.20 EGG11335.1 - 0.098 13.0 0.4 1.8 8.9 0.2 2.3 2 0 0 2 2 2 0 PRD domain F-box-like PF12937.7 EGG11336.1 - 0.056 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like Importin_rep_4 PF18808.1 EGG11336.1 - 0.15 12.4 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 Importin repeat LRR_8 PF13855.6 EGG11336.1 - 0.17 11.7 4.3 1.4 8.7 0.0 4.1 5 2 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.7 EGG11336.1 - 0.8 10.2 17.5 1.5 9.4 0.1 6.2 3 2 5 8 8 8 0 Leucine Rich repeats (2 copies) AMPK1_CBM PF16561.5 EGG11337.1 - 7.4e-27 93.4 0.0 1.4e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EGG11337.1 - 1.1e-23 83.2 2.1 1.4e-23 83.0 0.1 2.3 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 EGG11337.1 - 0.00018 22.0 5.6 0.00021 21.8 0.0 2.8 3 0 0 3 3 3 1 Starch/carbohydrate-binding module (family 53) Macoilin PF09726.9 EGG11337.1 - 3.2 6.2 13.0 4.2 5.8 13.0 1.1 1 0 0 1 1 1 0 Macoilin family Ras PF00071.22 EGG11338.1 - 1.9e-55 186.9 0.0 2.2e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG11338.1 - 4e-22 78.7 0.0 6.7e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG11338.1 - 2.5e-07 30.3 0.0 3.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_pol_Rpb8 PF03870.15 EGG11339.1 - 4.1e-49 166.4 0.0 4.5e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 zf-C2HE PF16278.5 EGG11340.1 - 0.04 14.4 0.1 0.1 13.1 0.1 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Trypan_PARP PF05887.11 EGG11340.1 - 0.45 10.5 6.8 1.4 8.9 6.8 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FUSC PF04632.12 EGG11341.1 - 0.062 11.8 4.2 0.11 11.1 4.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family WD40 PF00400.32 EGG11342.1 - 0.00038 21.2 6.3 0.17 12.8 0.4 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1367 PF07105.11 EGG11342.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) Pkinase PF00069.25 EGG11343.1 - 2.1e-50 171.6 0.4 4.1e-49 167.3 0.0 2.7 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11343.1 - 8e-23 81.0 0.0 1.5e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TFIIA PF03153.13 EGG11343.1 - 0.29 11.1 24.6 1.4 8.9 16.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 EGG11343.1 - 1.9 8.0 8.6 7.3 6.1 0.0 3.0 3 0 0 3 3 3 0 PPP4R2 TCP PF03634.13 EGG11343.1 - 8.7 6.9 20.6 7.2 7.2 5.0 2.2 2 0 0 2 2 2 0 TCP family transcription factor Ribosomal_L27A PF00828.19 EGG11344.1 - 4.9e-34 117.8 0.0 7.4e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Nup192 PF11894.8 EGG11345.1 - 1.4e-274 914.2 6.0 1.8e-274 913.9 6.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 WD40 PF00400.32 EGG11347.1 - 5.4e-23 80.8 23.1 0.0031 18.3 0.5 8.9 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG11347.1 - 8.1e-17 61.3 3.5 0.0012 19.1 0.0 6.0 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG11347.1 - 5.1e-07 29.3 3.3 0.00025 20.5 1.2 3.9 3 1 0 3 3 3 2 WD40-like domain RAB3GAP2_N PF14655.6 EGG11347.1 - 0.025 13.9 0.1 3 7.0 0.0 3.0 3 1 1 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med21 PF11221.8 EGG11349.1 - 2.5e-20 73.2 10.7 7.6e-20 71.6 1.3 2.5 1 1 2 3 3 3 2 Subunit 21 of Mediator complex Macoilin PF09726.9 EGG11349.1 - 0.022 13.3 3.2 0.037 12.6 3.0 1.4 1 1 0 1 1 1 0 Macoilin family SAS4 PF15460.6 EGG11349.1 - 0.17 12.0 2.6 1.7 8.8 0.2 2.2 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 Fungal_trans_2 PF11951.8 EGG11349.1 - 0.17 10.6 1.1 0.37 9.5 0.2 1.8 1 1 1 2 2 2 0 Fungal specific transcription factor domain Com_YlbF PF06133.11 EGG11349.1 - 1.1 10.0 6.1 1.9 9.1 0.5 2.6 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA ETF PF01012.21 EGG11352.1 - 2.3e-36 125.4 0.0 2.7e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain MvaI_BcnI PF15515.6 EGG11352.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family ERAP1_C PF11838.8 EGG11353.1 - 3.1e-81 273.4 0.0 4.8e-81 272.7 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EGG11353.1 - 1e-66 224.6 0.0 1.6e-66 224.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EGG11353.1 - 1.1e-39 136.5 0.2 2.4e-37 128.9 0.2 2.6 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain CDC37_N PF03234.14 EGG11354.1 - 3.3e-35 121.8 7.2 3.5e-35 121.7 7.2 1.0 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding PRP1_N PF06424.12 EGG11354.1 - 0.69 10.3 6.1 0.75 10.2 6.1 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Omptin PF01278.20 EGG11355.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Omptin family Alpha_kinase PF02816.18 EGG11357.1 - 1.1e-11 45.2 0.0 2.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family RMI1_N PF08585.12 EGG11358.1 - 0.061 13.1 1.4 0.08 12.7 1.4 1.2 1 0 0 1 1 1 0 RecQ mediated genome instability protein Cue1_U7BR PF18499.1 EGG11359.1 - 0.088 12.9 0.3 0.3 11.2 0.3 1.8 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 Cue1_U7BR PF18499.1 EGG11360.1 - 0.21 11.7 0.3 0.49 10.5 0.3 1.6 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 Pkinase PF00069.25 EGG11362.1 - 1.8e-43 148.8 0.0 2e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11362.1 - 5.1e-29 101.3 0.0 6.9e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG11362.1 - 0.013 15.4 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG11362.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGG11362.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EGG11362.1 - 0.046 13.0 0.0 0.087 12.1 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EGG11362.1 - 0.23 10.3 0.2 0.34 9.8 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EGG11362.1 - 0.25 10.1 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF3759 PF12585.8 EGG11363.1 - 5.7e-37 125.6 6.4 7.4e-37 125.3 6.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Duffy_binding PF05424.11 EGG11363.1 - 0.024 14.7 0.8 0.034 14.2 0.8 1.4 1 1 0 1 1 1 0 Duffy binding domain AOX PF01786.17 EGG11365.1 - 4.2e-92 307.6 0.0 5.3e-92 307.3 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase zf-C2H2 PF00096.26 EGG11366.1 - 1.2e-14 53.8 63.0 0.011 16.2 3.9 9.8 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG11366.1 - 2e-11 43.7 60.9 0.027 15.3 2.4 9.9 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGG11366.1 - 1.9e-06 28.0 30.5 0.077 13.3 2.1 8.4 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EGG11366.1 - 0.00015 22.0 4.4 0.00015 22.0 4.4 9.9 10 2 1 11 11 11 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGG11366.1 - 0.29 11.2 41.2 0.14 12.2 0.6 8.2 8 1 0 8 8 8 0 C2H2-type zinc finger Pox_L3_FP4 PF03339.14 EGG11366.1 - 6.9 5.6 7.5 0.81 8.6 2.1 2.0 1 1 1 2 2 2 0 Poxvirus L3/FP4 protein DUF333 PF03891.15 EGG11370.1 - 0.021 15.0 0.4 0.053 13.7 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF333) OKR_DC_1 PF01276.20 EGG11370.1 - 0.13 11.0 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain F-box-like PF12937.7 EGG11371.1 - 0.00065 19.5 0.0 0.002 18.0 0.0 1.9 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 EGG11371.1 - 0.038 14.0 0.1 2.8 7.9 0.0 3.1 3 0 0 3 3 3 0 F-box-like domain LRR_4 PF12799.7 EGG11371.1 - 0.15 12.5 6.7 4.1 8.0 1.0 4.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF2931 PF11153.8 EGG11371.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) WD40 PF00400.32 EGG11373.1 - 2.6e-14 53.4 8.9 2e-07 31.6 0.2 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG11373.1 - 9.7e-07 29.0 0.6 0.079 13.3 0.0 4.2 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain FMO-like PF00743.19 EGG11376.1 - 4.2e-15 55.2 0.0 4.4e-14 51.8 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGG11376.1 - 2.6e-13 49.9 0.2 7.9e-13 48.3 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG11376.1 - 1.7e-11 43.9 0.1 7.1e-09 35.3 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG11376.1 - 1.4e-10 41.2 0.6 1.3e-07 31.7 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGG11376.1 - 5.2e-10 39.7 0.6 0.0015 19.1 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGG11376.1 - 2.7e-08 33.3 0.0 5.2e-06 25.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EGG11376.1 - 1.9e-07 30.6 0.3 0.0029 16.9 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EGG11376.1 - 2.5e-07 30.8 1.2 0.0001 22.4 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 EGG11376.1 - 7.9e-07 29.0 5.8 5.5e-06 26.2 0.9 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG11376.1 - 2.2e-06 26.7 2.2 0.02 13.6 0.3 2.5 3 0 0 3 3 3 2 HI0933-like protein Amino_oxidase PF01593.24 EGG11376.1 - 2.5e-06 27.0 0.0 0.0094 15.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 EGG11376.1 - 3e-05 24.1 0.7 0.3 11.2 0.1 2.6 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 EGG11376.1 - 3.6e-05 23.0 1.5 0.096 11.7 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A 3HCDH_N PF02737.18 EGG11376.1 - 4.6e-05 23.4 0.9 0.0011 18.9 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EGG11376.1 - 0.00015 22.2 0.0 0.18 12.3 0.0 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.17 EGG11376.1 - 0.00027 20.2 2.2 0.045 13.0 0.2 2.8 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.24 EGG11376.1 - 0.00052 19.2 3.4 0.01 14.9 0.3 2.6 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EGG11376.1 - 0.0012 18.2 0.1 0.92 8.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EGG11376.1 - 0.004 16.3 0.1 1.7 7.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.7 EGG11376.1 - 0.0044 16.4 6.1 0.16 11.3 0.2 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGG11376.1 - 0.012 14.9 3.3 0.032 13.5 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_2 PF03446.15 EGG11376.1 - 0.051 13.7 0.3 0.09 12.9 0.0 1.5 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MCRA PF06100.11 EGG11376.1 - 0.069 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 MCRA family IlvN PF07991.12 EGG11376.1 - 0.11 12.1 2.0 3.9 7.0 0.1 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 EGG11376.1 - 0.18 11.8 2.2 1.2 9.1 0.1 2.4 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF962 PF06127.11 EGG11377.1 - 0.089 12.9 0.6 0.73 10.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Band_7 PF01145.25 EGG11378.1 - 3e-22 79.5 4.1 4.5e-22 78.9 3.7 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family RabGAP-TBC PF00566.18 EGG11379.1 - 1.4e-53 181.7 0.2 1.9e-53 181.3 0.2 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GAGA PF09237.11 EGG11380.1 - 0.16 11.8 0.1 0.6 10.0 0.1 1.9 1 0 0 1 1 1 0 GAGA factor SecG PF03840.14 EGG11381.1 - 0.35 11.0 2.4 0.4 10.8 0.0 2.3 2 1 1 3 3 3 0 Preprotein translocase SecG subunit DUF4272 PF14094.6 EGG11384.1 - 0.018 14.3 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) SRP68 PF16969.5 EGG11385.1 - 0.019 14.0 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 Tox-GHH PF15636.6 EGG11386.1 - 0.011 15.7 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin TTSSLRR PF12468.8 EGG11388.1 - 0.071 13.4 0.4 0.19 12.0 0.4 1.7 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein baeRF_family5 PF18846.1 EGG11389.1 - 0.015 15.5 0.2 0.032 14.4 0.2 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 DUF4493 PF14900.6 EGG11393.1 - 0.18 11.6 2.2 0.2 11.5 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4493) Ribosomal_L35p PF01632.19 EGG11394.1 - 2.9e-18 66.1 9.9 6.6e-18 65.0 9.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L35 Ecl1 PF12855.7 EGG11394.1 - 0.054 14.7 2.6 0.068 14.3 2.6 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins LptF_LptG PF03739.14 EGG11394.1 - 0.13 11.1 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG FOXP-CC PF16159.5 EGG11395.1 - 0.0012 19.5 2.0 1.3 9.7 0.1 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-Di19 PF05605.12 EGG11395.1 - 0.031 14.6 0.1 0.049 13.9 0.1 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.18 EGG11395.1 - 0.15 12.8 0.8 5.4 7.8 0.0 2.0 1 1 0 2 2 2 0 TRAF-type zinc finger zf-H2C2_2 PF13465.6 EGG11395.1 - 4.2 8.0 5.4 1.6 9.3 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Abhydrolase_1 PF00561.20 EGG11396.1 - 1.5e-05 24.8 0.0 8.8e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold FAM176 PF14851.6 EGG11397.1 - 1.9 8.1 3.8 31 4.2 1.7 2.3 2 0 0 2 2 2 0 FAM176 family Peptidase_S24 PF00717.23 EGG11400.1 - 1.3e-08 34.7 0.0 3.4e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase S24-like Ribosomal_S10 PF00338.22 EGG11401.1 - 0.011 15.9 0.2 0.02 15.1 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e MCM PF00493.23 EGG11402.1 - 2e-104 347.6 0.1 3.1e-104 347.0 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGG11402.1 - 4e-34 117.2 0.0 7.6e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGG11402.1 - 1.1e-27 96.2 0.4 2.8e-27 95.0 0.4 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGG11402.1 - 7.7e-16 58.6 0.2 2e-15 57.2 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGG11402.1 - 3.1e-06 26.7 0.0 0.00062 19.2 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGG11402.1 - 7e-06 26.1 0.0 3.1e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGG11402.1 - 0.00015 21.7 0.1 0.0012 18.7 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EGG11402.1 - 0.026 15.1 1.5 0.11 13.2 0.4 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal Sigma54_activat PF00158.26 EGG11402.1 - 0.036 13.8 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Proteasome PF00227.26 EGG11403.1 - 2e-42 144.8 0.0 2.3e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M24 PF00557.24 EGG11404.1 - 1.7e-42 145.5 0.1 2.1e-42 145.2 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 NST1 PF13945.6 EGG11404.1 - 0.058 13.5 3.4 0.083 13.0 3.4 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator PGA2 PF07543.12 EGG11404.1 - 4.2 7.3 9.5 0.81 9.7 3.5 2.5 3 0 0 3 3 3 0 Protein trafficking PGA2 Cnd2 PF05786.14 EGG11404.1 - 5.2 5.6 8.5 9.2 4.8 8.5 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 Pdase_C33_assoc PF14756.6 EGG11405.1 - 0.0031 17.4 1.2 0.0034 17.3 1.2 1.2 1 0 0 1 1 1 1 Peptidase_C33-associated domain NPV_P10 PF05531.12 EGG11407.1 - 0.0097 16.4 3.9 0.11 13.0 0.0 3.9 4 0 0 4 4 4 1 Nucleopolyhedrovirus P10 protein Med9 PF07544.13 EGG11407.1 - 0.65 10.1 10.4 0.83 9.8 3.0 4.0 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Lebercilin PF15619.6 EGG11407.1 - 1 9.0 15.6 0.43 10.2 9.2 3.0 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease AKNA PF12443.8 EGG11407.1 - 1.5 9.5 7.3 5.9 7.6 6.1 2.7 1 1 1 2 2 2 0 AT-hook-containing transcription factor Csm1_N PF18504.1 EGG11407.1 - 4.2 7.8 9.3 1.7 9.0 1.0 3.5 2 1 1 3 3 3 0 Csm1 N-terminal domain Occludin_ELL PF07303.13 EGG11407.1 - 6.7 7.5 9.5 1.6 9.5 4.5 2.6 2 1 1 3 3 3 0 Occludin homology domain Peptidase_C48 PF02902.19 EGG11411.1 - 6.9e-11 42.4 0.3 1.1e-10 41.8 0.3 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Vps54_N PF10475.9 EGG11415.1 - 0.012 15.0 10.0 0.025 13.8 10.0 1.5 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex DUF4320 PF14208.6 EGG11415.1 - 0.016 15.3 0.5 0.038 14.1 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) DUF445 PF04286.12 EGG11415.1 - 0.13 12.1 5.8 0.18 11.6 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) GM_CSF PF01109.17 EGG11415.1 - 2.7 8.2 8.0 5.7 7.1 4.0 2.5 1 1 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor BBS2_N PF14781.6 EGG11416.1 - 0.13 12.1 2.4 0.24 11.3 2.0 1.5 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal MRG PF05712.13 EGG11418.1 - 7.2e-19 67.9 0.2 9.2e-19 67.5 0.2 1.1 1 0 0 1 1 1 1 MRG DUF4218 PF13960.6 EGG11422.1 - 0.00027 20.5 0.0 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Fic_N PF13784.6 EGG11423.1 - 0.037 14.1 0.0 0.052 13.6 0.0 1.1 1 0 0 1 1 1 0 Fic/DOC family N-terminal Methyltransf_PK PF05891.12 EGG11424.1 - 0.0034 16.9 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase FliMN_C PF01052.20 EGG11428.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term GTP_EFTU PF00009.27 EGG11429.1 - 1.3e-46 158.6 0.0 1.9e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EGG11429.1 - 1.1e-32 113.2 0.1 1.9e-32 112.4 0.1 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EGG11429.1 - 4.1e-23 81.5 0.0 8.4e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EGG11429.1 - 2.9e-20 72.1 0.0 6.3e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGG11429.1 - 1.2e-07 32.0 0.1 2.5e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGG11429.1 - 1.3e-06 28.5 0.1 2.4e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EGG11429.1 - 0.00039 20.5 0.0 0.0011 19.0 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II SRPRB PF09439.10 EGG11429.1 - 0.0014 18.1 0.1 0.0027 17.1 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGG11429.1 - 0.032 14.4 0.0 0.2 11.9 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EGG11429.1 - 0.033 14.2 0.0 0.71 9.9 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Septin PF00735.18 EGG11429.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Septin Ras PF00071.22 EGG11429.1 - 0.12 11.9 0.0 0.44 10.1 0.0 1.8 1 1 0 1 1 1 0 Ras family GTP_cyclohydroI PF01227.22 EGG11430.1 - 2.3e-74 248.7 0.1 2.9e-74 248.3 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EGG11430.1 - 0.00022 21.3 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein IBN_N PF03810.19 EGG11431.1 - 1.8e-05 24.5 1.0 7.9e-05 22.5 0.0 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 EGG11431.1 - 0.00011 21.1 0.0 0.00059 18.8 0.0 2.2 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.12 EGG11431.1 - 0.0098 16.0 1.6 0.19 11.8 0.0 4.1 5 1 0 5 5 5 1 Exportin 1-like protein FliT PF05400.13 EGG11431.1 - 0.14 13.0 0.0 0.92 10.4 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein FliT Peptidase_M16 PF00675.20 EGG11432.1 - 7.6e-19 68.2 0.0 1.3e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGG11432.1 - 2.4e-05 24.4 0.1 0.00019 21.5 0.0 2.7 2 1 0 2 2 2 1 Peptidase M16 inactive domain HLH PF00010.26 EGG11433.1 - 5.7e-12 45.4 0.1 1.9e-11 43.7 0.1 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain XRCC4 PF06632.12 EGG11433.1 - 0.12 11.2 0.1 0.23 10.3 0.1 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 FXMRP1_C_core PF12235.8 EGG11436.1 - 0.018 15.7 11.4 0.018 15.7 11.4 2.9 3 0 0 3 3 3 0 Fragile X-related 1 protein core C terminal Tub_N PF16322.5 EGG11436.1 - 0.35 11.3 8.8 0.62 10.4 8.8 1.4 1 0 0 1 1 1 0 Tubby N-terminal Pox_Ag35 PF03286.14 EGG11437.1 - 0.26 11.0 9.9 0.31 10.8 9.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein V-SNARE PF05008.15 EGG11441.1 - 6.3e-18 64.9 7.8 4.9e-16 58.9 3.0 2.8 2 1 1 3 3 3 2 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EGG11441.1 - 1.1e-15 57.7 3.1 1.1e-15 57.7 3.1 2.1 2 0 0 2 2 1 1 Snare region anchored in the vesicle membrane C-terminus APG17 PF04108.12 EGG11441.1 - 0.009 15.2 6.1 0.051 12.7 2.1 2.1 1 1 1 2 2 2 1 Autophagy protein Apg17 Baculo_PEP_C PF04513.12 EGG11441.1 - 0.029 14.4 6.0 0.21 11.6 2.1 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_I PF06008.14 EGG11441.1 - 0.037 13.7 9.5 0.038 13.7 2.5 2.4 2 1 0 2 2 2 0 Laminin Domain I Prominin PF05478.11 EGG11441.1 - 0.037 12.0 5.4 0.09 10.7 5.4 1.6 1 1 0 1 1 1 0 Prominin RIFIN PF02009.16 EGG11441.1 - 0.044 13.7 0.2 0.062 13.2 0.2 1.3 1 1 0 1 1 1 0 Rifin DUF3825 PF12873.7 EGG11441.1 - 0.094 12.2 0.3 4.1 6.8 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3825) DASH_Duo1 PF08651.10 EGG11441.1 - 0.16 11.7 5.2 0.55 10.0 0.1 3.2 3 1 1 4 4 4 0 DASH complex subunit Duo1 YqjK PF13997.6 EGG11441.1 - 0.24 11.7 1.6 3 8.2 0.2 2.4 2 0 0 2 2 2 0 YqjK-like protein BshC PF10079.9 EGG11441.1 - 0.26 10.0 5.3 0.21 10.3 4.1 1.5 1 1 0 1 1 1 0 Bacillithiol biosynthesis BshC Exonuc_VII_L PF02601.15 EGG11441.1 - 0.3 10.6 10.5 1.5 8.3 10.5 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit CCDC-167 PF15188.6 EGG11441.1 - 0.32 11.4 6.1 23 5.4 6.0 2.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 V-ATPase_G_2 PF16999.5 EGG11441.1 - 1.3 9.5 7.5 0.49 10.8 2.6 2.5 2 2 1 3 3 3 0 Vacuolar (H+)-ATPase G subunit OmpH PF03938.14 EGG11441.1 - 1.4 9.3 7.3 0.93 9.8 4.0 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) zf-CpG_bind_C PF12269.8 EGG11441.1 - 1.7 8.4 3.8 9.9 5.9 1.7 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain HrpB7 PF09486.10 EGG11441.1 - 2.5 8.5 10.3 0.31 11.4 0.8 2.6 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FapA PF03961.13 EGG11441.1 - 2.9 6.4 6.6 35 2.8 6.7 2.0 1 1 0 1 1 1 0 Flagellar Assembly Protein A FliT PF05400.13 EGG11441.1 - 8.3 7.3 9.3 0.29 12.0 2.3 2.2 2 1 0 2 2 2 0 Flagellar protein FliT RPA43_OB PF17875.1 EGG11442.1 - 1.4e-19 70.9 0.3 2e-18 67.2 0.0 2.7 3 0 0 3 3 3 1 RPA43 OB domain in RNA Pol I RepA_C PF04796.12 EGG11443.1 - 0.064 13.3 0.1 0.098 12.7 0.1 1.2 1 0 0 1 1 1 0 Plasmid encoded RepA protein Ribonuc_red_lgN PF00317.21 EGG11445.1 - 0.061 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain N36 PF11438.8 EGG11445.1 - 0.12 12.2 0.6 30 4.6 0.0 3.1 3 0 0 3 3 3 0 36-mer N-terminal peptide of the N protein (N36) Ribosomal_L5e PF17144.4 EGG11447.1 - 1.9e-84 281.6 0.0 3.3e-84 280.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EGG11447.1 - 4.1e-29 101.4 6.4 4.1e-29 101.4 6.4 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 EGG11447.1 - 0.17 12.3 0.1 0.17 12.3 0.1 2.3 3 0 0 3 3 3 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Aminotran_5 PF00266.19 EGG11448.1 - 5.1e-92 308.7 0.0 5.9e-92 308.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGG11448.1 - 1.1e-05 24.9 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGG11448.1 - 0.0002 20.8 0.2 0.00054 19.4 0.2 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family B12-binding PF02310.19 EGG11448.1 - 0.017 15.1 0.1 0.77 9.8 0.0 2.5 2 0 0 2 2 2 0 B12 binding domain Cauli_AT PF03233.13 EGG11449.1 - 0.044 13.7 0.5 0.044 13.7 0.5 1.9 2 1 0 2 2 2 0 Aphid transmission protein DUF1870 PF08965.10 EGG11449.1 - 2.6 8.1 4.2 16 5.5 0.3 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1870) VIR_N PF15912.5 EGG11452.1 - 2.6e-06 27.2 0.0 2.6e-06 27.2 0.0 3.3 2 1 1 3 3 3 1 Virilizer, N-terminal DUF3196 PF11428.8 EGG11454.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) DNA_alkylation PF08713.11 EGG11455.1 - 0.028 14.1 0.3 1.5 8.5 0.0 2.0 1 1 1 2 2 2 0 DNA alkylation repair enzyme Amnionless PF14828.6 EGG11455.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Vac7 PF12751.7 EGG11456.1 - 0.0022 17.5 3.0 0.005 16.3 3.0 1.4 1 1 0 1 1 1 1 Vacuolar segregation subunit 7 ORC6 PF05460.13 EGG11456.1 - 0.75 9.0 10.7 1 8.6 10.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SQS_PSY PF00494.19 EGG11457.1 - 7.8e-27 94.4 0.0 1e-26 94.0 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase FAM86 PF14904.6 EGG11457.1 - 0.45 10.6 3.3 5.2 7.2 0.1 2.9 2 1 1 3 3 3 0 Family of unknown function RNase_PH PF01138.21 EGG11458.1 - 5e-23 82.0 0.1 7.2e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGG11458.1 - 0.00097 19.1 0.0 0.0031 17.5 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 TBCC PF07986.12 EGG11459.1 - 2.3e-11 43.5 0.3 6.9e-11 41.9 0.3 1.8 1 1 0 1 1 1 1 Tubulin binding cofactor C TcdB_N PF12918.7 EGG11459.1 - 0.73 10.2 4.8 11 6.4 0.6 2.6 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain FlxA PF14282.6 EGG11459.1 - 1.1 9.3 5.1 0.33 11.0 0.6 2.1 2 0 0 2 2 2 0 FlxA-like protein E1_dh PF00676.20 EGG11462.1 - 8.5e-88 294.2 0.0 1e-87 293.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 EGG11462.1 - 0.00011 21.3 0.1 0.00015 20.8 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Y_phosphatase2 PF03162.13 EGG11463.1 - 5e-40 136.8 0.0 7.9e-40 136.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGG11463.1 - 2.1e-05 24.6 0.0 5.3e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family SOG2 PF10428.9 EGG11463.1 - 0.14 11.3 14.9 0.31 10.2 14.7 1.6 2 0 0 2 2 2 0 RAM signalling pathway protein DUF2766 PF10964.8 EGG11463.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2766) DUF4663 PF15668.5 EGG11463.1 - 5.2 6.0 6.8 7.4 5.5 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) MINDY_DUB PF04424.13 EGG11467.1 - 0.022 14.8 0.6 5.4 7.1 0.1 3.2 3 0 0 3 3 3 0 MINDY deubiquitinase PXT1 PF15214.6 EGG11467.1 - 0.071 13.5 0.4 0.19 12.1 0.4 1.7 1 0 0 1 1 1 0 Peroxisomal testis-specific protein 1 Keratin_2_head PF16208.5 EGG11467.1 - 0.23 11.6 40.3 0.047 13.8 8.9 2.6 2 1 0 2 2 2 0 Keratin type II head MspA PF09203.11 EGG11467.1 - 0.23 11.3 15.0 1.1 9.1 6.4 2.6 2 0 0 2 2 2 0 MspA DUF5320 PF17253.2 EGG11467.1 - 3.9 8.6 9.5 5.2 8.2 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5320) WD40 PF00400.32 EGG11470.1 - 1.8e-12 47.6 11.8 4e-06 27.5 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 EGG11470.1 - 0.00044 19.0 0.4 0.13 10.9 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EGG11470.1 - 0.068 13.2 0.1 3 7.9 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Sigma70_r1_2 PF00140.20 EGG11470.1 - 0.29 11.2 1.4 0.49 10.4 1.4 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Ist1 PF03398.14 EGG11471.1 - 1.4e-58 197.5 3.0 1.6e-58 197.3 3.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RelB PF04221.12 EGG11471.1 - 0.033 14.1 0.1 0.069 13.1 0.1 1.5 1 0 0 1 1 1 0 RelB antitoxin EF-hand_7 PF13499.6 EGG11472.1 - 7.4e-08 32.7 0.3 7.4e-08 32.7 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGG11472.1 - 1.5e-07 30.7 0.2 0.014 15.2 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGG11472.1 - 1.9e-07 30.1 0.4 0.00014 21.1 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGG11472.1 - 1.5e-06 27.4 0.0 0.0011 18.4 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGG11472.1 - 0.017 14.9 0.0 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGG11472.1 - 0.83 10.0 7.5 3 8.2 0.6 3.1 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Sensor PF13796.6 EGG11478.1 - 0.46 10.5 10.0 0.025 14.6 3.5 1.9 2 0 0 2 2 2 0 Putative sensor DUF2593 PF10767.9 EGG11478.1 - 5.7 7.0 9.9 0.31 11.1 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2593) EF1_GNE PF00736.19 EGG11479.1 - 1e-31 108.9 1.2 1e-31 108.9 1.2 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EGG11479.1 - 5.7e-13 49.1 5.5 5.7e-13 49.1 5.5 2.4 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_6 PF17171.4 EGG11479.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG11479.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Peptidase_M16 PF00675.20 EGG11482.1 - 6.6e-37 126.8 0.0 1.1e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGG11482.1 - 4.5e-29 101.8 0.0 1.6e-28 100.0 0.0 2.0 1 1 0 1 1 1 1 Peptidase M16 inactive domain Pkinase PF00069.25 EGG11483.1 - 4.7e-14 52.4 0.0 5.7e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11483.1 - 3.4e-07 29.8 0.0 4.2e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2782 PF11191.8 EGG11483.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2782) RhoGEF PF00621.20 EGG11484.1 - 8.7e-26 91.3 0.0 4.8e-25 88.8 0.0 2.0 1 1 0 1 1 1 1 RhoGEF domain zf-CCHC PF00098.23 EGG11486.1 - 0.01 15.9 1.5 0.022 14.8 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle FKBP_C PF00254.28 EGG11487.1 - 9.6e-35 118.8 0.0 1.2e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ART PF01129.18 EGG11488.1 - 0.055 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase RR_TM4-6 PF06459.12 EGG11490.1 - 0.87 9.4 4.3 1.1 9.1 4.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EGG11490.1 - 2.2 6.9 4.6 2.6 6.7 4.6 1.0 1 0 0 1 1 1 0 Presenilin DUF2829 PF11195.8 EGG11495.1 - 0.3 11.4 1.7 1.3 9.4 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) Prefoldin_2 PF01920.20 EGG11501.1 - 1.4e-07 31.4 6.9 1.4e-07 31.4 6.9 1.7 1 1 0 1 1 1 1 Prefoldin subunit DUF3683 PF12447.8 EGG11501.1 - 0.0047 17.0 0.5 0.0089 16.2 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3683) MutS_III PF05192.18 EGG11501.1 - 0.0075 16.5 5.3 0.0089 16.3 5.3 1.1 1 0 0 1 1 1 1 MutS domain III FlaC_arch PF05377.11 EGG11501.1 - 0.14 12.5 0.6 0.14 12.5 0.6 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) YjcZ PF13990.6 EGG11501.1 - 0.33 10.3 2.1 0.4 10.0 2.1 1.1 1 0 0 1 1 1 0 YjcZ-like protein Aida_N PF08910.10 EGG11501.1 - 1.1 9.6 4.3 0.54 10.7 0.6 2.0 2 0 0 2 2 2 0 Aida N-terminus KxDL PF10241.9 EGG11501.1 - 2.1 8.7 9.0 3 8.2 1.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein zf-C2HC5 PF06221.13 EGG11502.1 - 1.7e-07 31.1 4.8 3.3e-07 30.2 4.8 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Gcd10p PF04189.13 EGG11505.1 - 1e-66 225.1 0.0 1.4e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family polyprenyl_synt PF00348.17 EGG11506.1 - 1.4e-62 211.0 0.0 2.4e-62 210.3 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Nepo_coat_C PF03688.14 EGG11507.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain Baculo_PEP_C PF04513.12 EGG11508.1 - 0.041 13.9 0.5 0.072 13.1 0.5 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 EGG11508.1 - 0.063 13.6 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Borrelia_REV PF03978.13 EGG11508.1 - 0.072 13.0 0.3 0.12 12.3 0.3 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Tektin PF03148.14 EGG11508.1 - 0.074 11.8 0.2 0.12 11.2 0.2 1.2 1 0 0 1 1 1 0 Tektin family Cluap1 PF10234.9 EGG11508.1 - 0.083 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 T4SS_TraI PF16932.5 EGG11508.1 - 0.088 12.0 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer DUF1043 PF06295.12 EGG11508.1 - 0.098 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Vert_IL3-reg_TF PF06529.11 EGG11511.1 - 0.0046 16.1 5.9 0.071 12.2 2.2 2.1 2 0 0 2 2 2 2 Vertebrate interleukin-3 regulated transcription factor CCSAP PF15748.5 EGG11511.1 - 0.23 11.6 15.9 0.28 11.3 15.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SOBP PF15279.6 EGG11511.1 - 0.26 11.9 10.3 0.32 11.6 10.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.14 EGG11511.1 - 1.1 7.5 8.2 1.2 7.4 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein MIF4G PF02854.19 EGG11512.1 - 3.1e-10 40.1 0.0 7.2e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 EGG11512.1 - 9.7e-05 22.3 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 MA3 domain Seryl_tRNA_N PF02403.22 EGG11512.1 - 1.2 9.4 8.4 0.39 11.0 1.8 3.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CDV3 PF15359.6 EGG11512.1 - 9.4 6.7 12.5 0.28 11.7 0.8 2.8 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 CUE PF02845.16 EGG11513.1 - 1.3e-07 31.2 0.0 1.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 EGG11513.1 - 0.098 12.8 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1296) FXMRP1_C_core PF12235.8 EGG11513.1 - 0.33 11.6 12.5 0.073 13.7 1.7 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Myosin_head PF00063.21 EGG11514.1 - 3.6e-230 765.8 0.2 4.5e-230 765.4 0.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGG11514.1 - 7.6e-54 182.2 0.0 1.3e-53 181.5 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 EGG11514.1 - 1.9e-12 46.8 0.3 5.6e-12 45.3 0.3 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGG11514.1 - 5.8e-10 38.7 0.3 1.9e-09 37.0 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EGG11514.1 - 5.2e-09 35.6 0.4 1.2e-08 34.4 0.4 1.7 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 EGG11514.1 - 0.0014 18.9 0.6 0.0031 17.8 0.6 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 EGG11514.1 - 0.01 15.7 0.4 0.022 14.6 0.4 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Zeta_toxin PF06414.12 EGG11514.1 - 0.02 14.2 2.4 0.57 9.4 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 EGG11514.1 - 0.033 14.6 0.1 0.12 12.8 0.0 2.0 2 0 0 2 2 1 0 AAA ATPase domain AAA_22 PF13401.6 EGG11514.1 - 0.055 13.7 0.1 0.16 12.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 EGG11514.1 - 0.089 12.3 0.1 5 6.6 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain IQ PF00612.27 EGG11514.1 - 0.18 11.7 6.5 1.9 8.5 0.3 2.9 1 1 1 2 2 2 0 IQ calmodulin-binding motif Mito_carr PF00153.27 EGG11517.1 - 6.5e-56 186.3 1.3 1.3e-17 63.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_43 PF04616.14 EGG11518.1 - 5.3e-30 104.7 0.1 7.2e-30 104.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.14 EGG11519.1 - 4.4e-31 108.3 0.3 6.5e-31 107.7 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Ig_2 PF13895.6 EGG11520.1 - 0.047 14.0 0.6 0.38 11.1 0.1 2.2 2 0 0 2 2 2 0 Immunoglobulin domain COX6A PF02046.15 EGG11521.1 - 7e-32 110.2 0.1 8.4e-32 110.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa CAP PF00188.26 EGG11522.1 - 6.9e-14 52.8 0.8 3e-13 50.7 0.5 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Velvet PF11754.8 EGG11523.1 - 1.1e-46 159.8 6.7 7.4e-31 108.0 0.0 3.3 3 1 1 4 4 4 3 Velvet factor Lgl_C PF08596.10 EGG11524.1 - 1.9e-11 43.3 0.0 2.5e-09 36.3 0.0 3.3 3 1 0 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 EGG11524.1 - 5.5e-05 23.9 2.6 0.009 16.8 0.0 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG11524.1 - 0.00018 21.8 0.0 0.043 14.1 0.0 3.9 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Synaptobrevin PF00957.21 EGG11524.1 - 0.0003 20.5 4.1 0.00063 19.5 4.1 1.4 1 0 0 1 1 1 1 Synaptobrevin IFT57 PF10498.9 EGG11524.1 - 0.26 10.2 1.9 0.47 9.4 1.9 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CAP PF00188.26 EGG11525.1 - 5.5e-17 62.8 0.4 9.7e-17 62.0 0.4 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Autophagy_act_C PF03987.15 EGG11526.1 - 6.8e-18 65.0 5.8 4.8e-17 62.3 5.8 2.3 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain HMG_box_2 PF09011.10 EGG11528.1 - 0.11 13.2 0.1 0.24 12.0 0.1 1.6 1 0 0 1 1 1 0 HMG-box domain WBP-1 PF11669.8 EGG11529.1 - 0.42 11.3 5.2 2.9 8.6 0.0 3.5 3 1 0 3 3 3 0 WW domain-binding protein 1 Shisa PF13908.6 EGG11529.1 - 2.1 8.6 0.0 2.1 8.6 0.0 3.9 3 1 0 4 4 4 0 Wnt and FGF inhibitory regulator PTS_EIIB PF00367.20 EGG11531.1 - 0.16 11.5 0.1 0.48 10.0 0.1 1.8 1 0 0 1 1 1 0 phosphotransferase system, EIIB Chlorosome_CsmC PF11098.8 EGG11531.1 - 0.35 10.8 3.8 0.51 10.3 3.8 1.2 1 0 0 1 1 1 0 Chlorosome envelope protein C Coiled PF05710.12 EGG11531.1 - 2.8 8.8 13.2 7.9 7.4 13.2 1.8 1 1 0 1 1 1 0 Coiled coil DnaJ PF00226.31 EGG11532.1 - 1.4e-11 44.3 0.2 1.4e-11 44.3 0.2 2.9 3 0 0 3 3 3 1 DnaJ domain GIT_SHD PF08518.11 EGG11533.1 - 3.6e-21 74.5 11.8 3.1e-10 39.5 3.8 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Tropomyosin PF00261.20 EGG11533.1 - 0.0011 18.4 38.5 0.0018 17.7 35.7 2.3 2 0 0 2 2 2 1 Tropomyosin TPR_MLP1_2 PF07926.12 EGG11533.1 - 0.011 15.7 18.8 0.011 15.7 18.8 3.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 EGG11533.1 - 0.049 13.7 33.2 0.12 12.5 14.7 3.7 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding PTPA PF03095.15 EGG11533.1 - 0.2 11.1 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein FAM184 PF15665.5 EGG11533.1 - 0.29 10.9 27.5 1 9.1 25.2 2.8 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B DUF3584 PF12128.8 EGG11533.1 - 0.31 8.5 28.8 0.71 7.3 24.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.11 EGG11533.1 - 0.48 10.2 18.0 0.016 15.1 4.3 3.8 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Lebercilin PF15619.6 EGG11533.1 - 1 9.0 32.3 0.12 12.0 18.6 3.3 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease CALCOCO1 PF07888.11 EGG11533.1 - 1.3 7.8 35.5 0.82 8.5 22.4 2.4 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 EGG11533.1 - 1.9 8.5 37.0 0.48 10.4 5.3 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 EGG11533.1 - 3.6 6.9 28.9 0.17 11.2 3.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Pox_A_type_inc PF04508.12 EGG11533.1 - 3.8 7.5 29.1 0.22 11.4 2.2 5.5 5 0 0 5 5 4 0 Viral A-type inclusion protein repeat V_ATPase_I PF01496.19 EGG11533.1 - 8.6 4.1 23.1 0.28 9.0 9.7 2.3 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Mito_carr PF00153.27 EGG11534.1 - 1.9e-34 117.4 2.6 2e-12 46.8 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein TetR_C_9 PF14514.6 EGG11534.1 - 0.1 12.7 0.0 8.7 6.5 0.0 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Sorb PF02208.16 EGG11535.1 - 0.05 13.5 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Sorbin homologous domain zf-C2H2_2 PF12756.7 EGG11535.1 - 0.051 13.9 0.1 0.094 13.1 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EGG11535.1 - 0.13 12.7 2.0 75 3.9 4.7 3.1 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGG11535.1 - 0.48 10.8 2.9 3.7 8.0 2.9 2.3 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AAA_6 PF12774.7 EGG11538.1 - 3e-129 430.7 0.0 1.3e-128 428.7 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EGG11538.1 - 1.9e-120 403.2 7.2 1.9e-120 403.2 7.2 4.8 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EGG11538.1 - 9.3e-114 380.6 6.9 9.3e-114 380.6 6.9 5.1 4 2 1 5 5 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EGG11538.1 - 4.4e-73 245.0 0.0 4.4e-73 245.0 0.0 3.3 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 EGG11538.1 - 1e-65 221.7 0.0 3.3e-65 220.0 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 EGG11538.1 - 6.1e-45 153.7 6.4 1.1e-44 152.9 6.4 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 EGG11538.1 - 1.9e-44 152.2 0.2 5.8e-44 150.5 0.2 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EGG11538.1 - 1.9e-40 138.3 0.0 8.2e-36 123.2 0.0 4.5 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGG11538.1 - 2.4e-38 131.5 0.0 9.7e-38 129.6 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGG11538.1 - 2.5e-29 101.8 0.8 2.2e-28 98.7 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EGG11538.1 - 6e-27 94.3 0.0 2.6e-11 43.7 0.0 5.9 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EGG11538.1 - 7e-17 61.7 0.0 4.7e-16 59.0 0.0 2.6 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EGG11538.1 - 9e-13 48.7 2.6 0.014 15.7 0.0 7.0 7 0 0 7 7 7 2 AAA domain AAA PF00004.29 EGG11538.1 - 6.7e-12 46.0 0.3 0.0063 16.9 0.0 5.3 6 0 0 6 6 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGG11538.1 - 2.7e-08 34.4 0.9 0.11 13.0 0.0 6.1 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.6 EGG11538.1 - 1.8e-07 31.4 7.3 0.62 10.2 0.0 5.7 6 0 0 6 6 4 3 AAA domain AAA_16 PF13191.6 EGG11538.1 - 2e-06 28.3 0.4 0.89 9.9 0.2 6.2 4 1 1 5 5 5 1 AAA ATPase domain T2SSE PF00437.20 EGG11538.1 - 6.6e-05 22.1 0.0 0.015 14.4 0.0 3.0 2 1 0 2 2 2 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 EGG11538.1 - 0.00018 21.0 0.1 0.97 8.8 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 EGG11538.1 - 0.00028 21.1 0.8 0.00089 19.4 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain AAA_19 PF13245.6 EGG11538.1 - 0.002 18.4 0.9 0.53 10.6 0.0 4.3 4 0 0 4 4 3 1 AAA domain FtsK_SpoIIIE PF01580.18 EGG11538.1 - 0.0026 17.2 0.0 0.42 9.9 0.0 3.4 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_30 PF13604.6 EGG11538.1 - 0.0067 16.2 0.5 40 3.8 0.0 4.6 4 0 0 4 4 4 0 AAA domain BRE1 PF08647.11 EGG11538.1 - 0.0077 16.3 0.3 0.0077 16.3 0.3 4.3 3 0 0 3 3 2 1 BRE1 E3 ubiquitin ligase LOH1CR12 PF10158.9 EGG11538.1 - 0.0084 16.1 3.5 3.9 7.5 0.2 4.5 2 0 0 2 2 2 1 Tumour suppressor protein AAA_24 PF13479.6 EGG11538.1 - 0.011 15.5 0.6 37 4.0 0.0 4.7 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 EGG11538.1 - 0.02 14.6 0.1 1.1 9.0 0.0 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_29 PF13555.6 EGG11538.1 - 0.022 14.5 0.0 1 9.2 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EGG11538.1 - 0.026 14.1 0.0 0.76 9.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGG11538.1 - 0.071 13.6 1.1 8.9 6.8 0.0 3.9 4 0 0 4 4 2 0 ABC transporter ERM PF00769.19 EGG11538.1 - 0.12 12.2 16.6 5.2 6.8 0.1 3.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family AAA_15 PF13175.6 EGG11538.1 - 0.13 11.9 3.8 0.37 10.4 2.1 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 EGG11538.1 - 0.53 10.0 6.9 1.8 8.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain Atg14 PF10186.9 EGG11538.1 - 9.6 5.2 14.2 2.3 7.2 8.9 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mpv17_PMP22 PF04117.12 EGG11539.1 - 1.5e-20 73.2 3.4 2.7e-20 72.3 3.4 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family DPBB_1 PF03330.18 EGG11541.1 - 0.00031 21.0 1.7 0.00086 19.5 0.5 2.3 2 1 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 EGG11541.1 - 0.00032 20.7 0.2 0.00055 19.9 0.2 1.4 1 0 0 1 1 1 1 Pollen allergen Complex1_49kDa PF00346.19 EGG11542.1 - 8.6e-120 398.9 0.0 1.2e-119 398.4 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EGG11542.1 - 0.0009 18.3 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase DUF202 PF02656.15 EGG11544.1 - 3.4e-18 65.8 0.2 1.5e-17 63.8 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF202) HMG_box_2 PF09011.10 EGG11545.1 - 0.016 15.8 0.1 0.045 14.3 0.1 1.8 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.19 EGG11545.1 - 0.03 14.7 0.0 0.074 13.5 0.0 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box zf-CCHC_3 PF13917.6 EGG11546.1 - 0.0098 15.8 0.3 0.016 15.2 0.3 1.3 1 0 0 1 1 1 1 Zinc knuckle CLIP1_ZNF PF16641.5 EGG11546.1 - 0.046 13.6 1.3 0.078 12.9 1.3 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle Copper-fist PF00649.18 EGG11546.1 - 0.18 11.3 0.7 0.34 10.4 0.7 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_6 PF15288.6 EGG11546.1 - 0.35 10.7 2.5 0.87 9.5 2.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGG11546.1 - 0.57 10.0 2.7 0.93 9.3 2.7 1.3 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.25 EGG11547.1 - 7.1e-71 238.7 0.0 8.9e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11547.1 - 1.8e-33 115.9 0.0 2.5e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGG11547.1 - 1.1e-10 42.1 4.1 1.1e-10 42.1 4.1 1.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGG11547.1 - 0.00041 19.4 0.0 0.00062 18.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EGG11547.1 - 0.0022 17.7 0.0 0.51 9.9 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGG11547.1 - 0.0025 17.2 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGG11547.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NADHdh-2_N PF12155.8 EGG11547.1 - 0.19 12.1 0.0 0.55 10.7 0.0 1.7 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal PIF1 PF05970.14 EGG11549.1 - 1.8e-24 86.6 0.0 3.4e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AFT PF08731.11 EGG11549.1 - 0.0011 19.4 0.1 0.0024 18.3 0.1 1.6 1 0 0 1 1 1 1 Transcription factor AFT AAA_15 PF13175.6 EGG11550.1 - 0.035 13.8 2.1 0.048 13.4 2.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain RRP36 PF06102.12 EGG11551.1 - 1e-18 67.8 27.2 5e-16 59.1 18.4 2.6 2 1 1 3 3 3 2 rRNA biogenesis protein RRP36 Trypan_PARP PF05887.11 EGG11551.1 - 0.038 14.0 3.0 0.075 13.0 3.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) tRNA_lig_kinase PF08303.11 EGG11551.1 - 0.16 12.0 3.9 0.14 12.3 1.5 2.0 1 1 1 2 2 2 0 tRNA ligase kinase domain DUF763 PF05559.11 EGG11551.1 - 0.31 10.2 4.1 0.17 11.1 1.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF763) Alpha_kinase PF02816.18 EGG11556.1 - 9.2e-32 110.6 1.2 1.3e-31 110.1 1.2 1.2 1 0 0 1 1 1 1 Alpha-kinase family Helicase_C PF00271.31 EGG11557.1 - 1e-10 41.9 0.1 2e-10 41.0 0.0 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain LPP20 PF02169.16 EGG11558.1 - 0.25 11.7 2.7 0.63 10.4 2.7 1.6 1 0 0 1 1 1 0 LPP20 lipoprotein Rho_N PF07498.12 EGG11561.1 - 1.7e-06 27.8 0.1 1.3e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain S8_pro-domain PF16470.5 EGG11563.1 - 0.016 15.9 0.7 0.044 14.6 0.2 2.0 2 0 0 2 2 2 0 Peptidase S8 pro-domain DUF4201 PF13870.6 EGG11563.1 - 0.042 13.6 0.7 0.066 12.9 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) ThiC-associated PF13667.6 EGG11565.1 - 0.0023 17.7 0.1 0.0048 16.7 0.1 1.5 1 0 0 1 1 1 1 ThiC-associated domain Gar1 PF04410.14 EGG11566.1 - 0.39 10.5 2.7 0.72 9.6 2.7 1.4 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region DDE_Tnp_1 PF01609.21 EGG11566.1 - 2.7 7.6 5.3 0.23 11.1 0.6 1.5 2 0 0 2 2 2 0 Transposase DDE domain G6PD_C PF02781.16 EGG11567.1 - 8e-112 373.1 0.0 1.4e-111 372.4 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EGG11567.1 - 4.4e-58 196.8 0.0 1.3e-57 195.3 0.0 1.8 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain IBN_N PF03810.19 EGG11568.1 - 0.00021 21.1 0.1 0.00055 19.8 0.1 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGG11568.1 - 0.051 13.6 2.3 2.1 8.4 0.1 4.4 3 2 0 4 4 4 0 Exportin 1-like protein ThrE PF06738.12 EGG11569.1 - 9.6e-34 116.8 2.4 9.6e-34 116.8 2.4 2.8 2 2 1 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EGG11569.1 - 4.6e-06 26.8 7.5 4.6e-06 26.8 7.5 2.5 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE Tombus_P33 PF08500.10 EGG11569.1 - 0.052 13.5 2.9 14 5.6 2.8 2.4 2 0 0 2 2 2 0 Tombusvirus p33 DUF4574 PF15141.6 EGG11569.1 - 0.14 12.0 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Ctr PF04145.15 EGG11569.1 - 2 9.0 6.4 17 6.0 6.4 2.4 1 1 0 1 1 1 0 Ctr copper transporter family Pkinase PF00069.25 EGG11571.1 - 1.1e-29 103.6 0.0 1.5e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11571.1 - 2.6e-16 59.7 0.0 3.2e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG11571.1 - 0.0083 15.5 0.0 0.015 14.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like CFEM PF05730.11 EGG11573.1 - 3.9e-12 46.1 14.4 5.7e-12 45.6 14.4 1.2 1 0 0 1 1 1 1 CFEM domain ABC2_membrane PF01061.24 EGG11574.1 - 2e-34 118.9 24.2 2e-34 118.9 24.2 3.1 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 EGG11574.1 - 6.7e-23 81.7 0.0 3.6e-22 79.4 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGG11574.1 - 5.3e-06 26.5 1.3 0.0061 16.4 0.2 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGG11574.1 - 0.0015 18.3 0.2 0.0033 17.1 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG11574.1 - 0.0096 15.8 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 EGG11574.1 - 0.026 14.4 0.0 0.074 13.0 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_22 PF13401.6 EGG11574.1 - 0.11 12.8 0.0 0.75 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EGG11574.1 - 0.19 11.2 0.1 14 5.0 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGG11574.1 - 0.2 12.2 0.1 0.32 11.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain DUF2681 PF10883.8 EGG11574.1 - 0.37 11.2 2.1 0.85 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) FixQ PF05545.11 EGG11574.1 - 2.8 8.0 4.7 54 3.9 2.2 2.9 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ SNN_transmemb PF09049.10 EGG11574.1 - 5.7 7.0 6.8 0.91 9.5 2.4 2.0 2 0 0 2 2 2 0 Stannin transmembrane SKG6 PF08693.10 EGG11574.1 - 7.4 6.1 6.6 0.46 9.9 0.4 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain PXA PF02194.15 EGG11575.1 - 2.7e-34 118.7 0.0 9e-34 117.0 0.0 1.9 1 1 0 1 1 1 1 PXA domain Nexin_C PF08628.12 EGG11575.1 - 3.3e-26 92.1 0.1 1.4e-25 90.0 0.0 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 EGG11575.1 - 1.5e-12 47.5 0.0 6.6e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 PX domain RGS PF00615.19 EGG11575.1 - 7.3e-06 26.3 0.1 0.00021 21.6 0.1 2.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain Fasciclin PF02469.22 EGG11578.1 - 0.00068 19.9 0.0 0.0032 17.7 0.0 2.1 1 1 0 1 1 1 1 Fasciclin domain DEAD PF00270.29 EGG11581.1 - 0.026 14.3 0.0 0.044 13.6 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase Pox_A30L_A26L PF06086.12 EGG11582.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein TFIIIC_sub6 PF10419.9 EGG11583.1 - 1.8e-17 63.0 0.0 3.6e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain DUF1571 PF07608.11 EGG11583.1 - 0.29 10.5 2.1 0.21 11.0 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1571) Pkinase PF00069.25 EGG11584.1 - 2.4e-08 33.7 0.0 0.0033 16.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11584.1 - 9.1e-07 28.4 0.0 0.00093 18.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EGG11585.1 - 3.4e-16 59.4 0.0 4.7e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11585.1 - 0.002 17.5 0.0 0.0059 15.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3759 PF12585.8 EGG11587.1 - 3.2e-20 72.0 9.9 3.8e-20 71.7 9.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3759) DUF678 PF05077.12 EGG11591.1 - 0.046 13.8 4.3 0.2 11.8 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) LCD1 PF09798.9 EGG11591.1 - 0.085 11.4 1.7 0.095 11.2 1.7 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Presenilin PF01080.17 EGG11591.1 - 4.8 5.9 4.7 5 5.8 4.7 1.1 1 0 0 1 1 1 0 Presenilin Calpain_u2 PF16648.5 EGG11591.1 - 7.5 7.1 12.0 47 4.5 10.9 2.4 1 1 1 2 2 2 0 Unstructured region on Calpain-3 U3_assoc_6 PF08640.11 EGG11592.1 - 7.2e-23 80.5 8.6 1.5e-22 79.5 1.4 3.7 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EGG11592.1 - 0.00013 22.5 0.0 0.11 13.3 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat Ku_PK_bind PF08785.11 EGG11592.1 - 0.0067 16.6 0.4 0.04 14.0 0.0 2.4 2 0 0 2 2 2 1 Ku C terminal domain like Coatomer_b_Cpla PF14806.6 EGG11592.1 - 0.049 13.6 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform NRDE-2 PF08424.10 EGG11592.1 - 0.071 12.2 3.4 2.3 7.3 0.0 3.9 4 0 0 4 4 4 0 NRDE-2, necessary for RNA interference MMM1 PF10296.9 EGG11594.1 - 1.1e-07 31.3 0.1 3.5e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 HisG PF01634.18 EGG11595.1 - 4.2e-51 173.1 0.1 5.2e-51 172.8 0.1 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EGG11595.1 - 6.3e-26 90.3 0.1 3.8e-25 87.8 0.0 2.1 2 0 0 2 2 2 1 HisG, C-terminal domain adh_short_C2 PF13561.6 EGG11596.1 - 1.2e-48 165.7 0.8 1.7e-48 165.2 0.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG11596.1 - 3.3e-36 124.6 0.6 4.4e-36 124.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG11596.1 - 1.7e-07 31.3 1.9 1.1e-06 28.7 1.9 1.9 1 1 0 1 1 1 1 KR domain MFS_1 PF07690.16 EGG11597.1 - 4.1e-47 160.8 41.3 6.9e-47 160.1 41.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EGG11597.1 - 6.8e-16 57.8 14.7 9.5e-16 57.3 14.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGG11597.1 - 1.4e-10 40.7 10.6 1.4e-10 40.7 10.6 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter LSM PF01423.22 EGG11598.1 - 1e-16 60.4 0.0 1.4e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.25 EGG11599.1 - 7.5e-19 68.1 0.1 7.8e-19 68.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11599.1 - 2.6e-10 40.0 0.0 2.7e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG11599.1 - 0.052 13.5 0.3 0.16 11.9 0.3 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF726 PF05277.12 EGG11602.1 - 5.4e-120 400.4 4.2 7.3e-120 400.0 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) CAML PF14963.6 EGG11602.1 - 1.5 8.9 8.3 2.8 8.0 8.3 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Dopey_N PF04118.14 EGG11604.1 - 6.4e-100 334.2 0.0 1.5e-99 333.0 0.0 1.7 1 0 0 1 1 1 1 Dopey, N-terminal LCM PF04072.14 EGG11605.1 - 6.6e-18 65.3 0.0 8.2e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Cupin_8 PF13621.6 EGG11606.1 - 1.7e-39 136.0 0.0 2.5e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGG11606.1 - 6.1e-10 39.1 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EGG11606.1 - 0.00067 20.1 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.22 EGG11606.1 - 0.032 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Cupin DLH PF01738.18 EGG11609.1 - 0.0091 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EGG11609.1 - 0.018 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 EGG11609.1 - 0.022 13.7 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EGG11609.1 - 0.049 13.1 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Chlorophyllase PF07224.11 EGG11609.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Sec63 PF02889.16 EGG11612.1 - 2.3e-159 528.3 0.2 5.4e-92 307.6 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGG11612.1 - 4.9e-46 156.7 0.0 5.2e-27 94.7 0.1 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EGG11612.1 - 1.6e-33 115.2 0.2 6.7e-33 113.2 0.2 2.2 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EGG11612.1 - 2.6e-24 86.1 0.0 2.5e-14 53.6 0.0 3.3 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGG11612.1 - 6.3e-12 45.8 0.0 3.6e-07 30.5 0.0 3.7 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGG11612.1 - 6e-08 33.1 0.0 0.0045 17.3 0.0 3.7 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 EGG11612.1 - 0.00051 19.2 0.0 0.069 12.2 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein PhoH PF02562.16 EGG11612.1 - 0.0019 17.7 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_7 PF12775.7 EGG11612.1 - 0.0042 16.6 0.0 2.3 7.7 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_11 PF13086.6 EGG11612.1 - 0.028 14.2 0.2 1.7 8.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain Cnd3 PF12719.7 EGG11613.1 - 6e-70 235.7 0.0 4.3e-69 232.9 0.0 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EGG11613.1 - 4.2e-09 36.7 1.7 0.00063 20.1 0.1 4.7 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.22 EGG11613.1 - 3.7e-05 23.6 2.8 9.6 6.8 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EGG11613.1 - 0.00027 21.0 8.8 0.52 10.3 1.1 4.7 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGG11613.1 - 0.0043 17.5 0.1 0.88 10.1 0.0 3.9 4 0 0 4 4 4 1 HEAT-like repeat Peptidase_M28 PF04389.17 EGG11615.1 - 7.5e-33 113.9 0.0 1.4e-32 113.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M28 Endosulfine PF04667.17 EGG11616.1 - 3.7e-25 87.9 0.1 6.5e-25 87.1 0.1 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region NCE101 PF11654.8 EGG11617.1 - 0.094 12.4 0.1 0.53 10.0 0.0 2.3 2 0 0 2 2 2 0 Non-classical export protein 1 BUD22 PF09073.10 EGG11617.1 - 0.16 11.3 23.1 0.28 10.5 23.1 1.4 1 0 0 1 1 1 0 BUD22 DUF1840 PF08895.11 EGG11617.1 - 0.55 10.6 3.7 1.3 9.4 3.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF1682 PF07946.14 EGG11617.1 - 0.8 8.9 8.6 1.5 8.0 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CNDH2_C PF16858.5 EGG11617.1 - 1.1 9.1 14.5 2.8 7.7 9.6 2.3 2 1 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Vfa1 PF08432.10 EGG11617.1 - 1.6 9.0 15.1 5.1 7.4 15.1 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sec62 PF03839.16 EGG11617.1 - 3.4 7.1 7.0 9.4 5.7 7.0 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S49_N PF08496.10 EGG11617.1 - 3.6 7.6 10.7 8.9 6.4 10.7 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CobT PF06213.12 EGG11617.1 - 4.1 6.7 22.9 7.6 5.8 22.9 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NARP1 PF12569.8 EGG11617.1 - 7.2 5.4 15.3 12 4.6 15.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Paf1 PF03985.13 EGG11617.1 - 9.4 5.1 25.2 8.4 5.3 22.0 2.0 2 0 0 2 2 2 0 Paf1 BRCA-2_OB1 PF09103.10 EGG11618.1 - 2.6e-25 88.8 0.0 4.6e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 EGG11618.1 - 6.6e-06 25.9 0.2 0.0011 18.6 0.3 2.3 1 1 1 2 2 2 2 BRCA2, helical DUF4542 PF15075.6 EGG11619.1 - 0.026 14.9 0.8 0.065 13.6 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) Alpha_kinase PF02816.18 EGG11620.1 - 8.1e-18 65.2 0.7 1.2e-17 64.7 0.7 1.2 1 0 0 1 1 1 1 Alpha-kinase family AMP-binding PF00501.28 EGG11621.1 - 3.8e-95 319.0 0.0 5.1e-95 318.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG11621.1 - 0.015 16.2 0.0 0.036 15.0 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Stealth_CR2 PF11380.8 EGG11622.1 - 0.0003 20.9 0.5 0.32 11.2 0.0 2.7 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 F-box PF00646.33 EGG11623.1 - 0.068 13.1 1.2 0.18 11.8 0.7 2.0 2 0 0 2 2 2 0 F-box domain RolB_RolC PF02027.17 EGG11623.1 - 0.075 12.7 0.1 0.91 9.2 0.0 2.2 2 1 0 2 2 2 0 RolB/RolC glucosidase family Hydrolase_3 PF08282.12 EGG11624.1 - 1.6e-49 168.9 0.0 1.8e-49 168.8 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGG11624.1 - 6.7e-10 38.9 0.0 7.6e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EGG11624.1 - 1.4e-05 25.5 0.0 0.0067 16.7 0.0 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGG11624.1 - 0.028 14.5 0.0 1.2 9.1 0.0 2.7 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG11624.1 - 0.11 12.9 0.0 0.54 10.6 0.0 2.1 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase CBM_2 PF00553.19 EGG11626.1 - 0.00019 21.7 16.0 0.0038 17.5 4.6 3.0 1 1 1 2 2 2 2 Cellulose binding domain Pkinase PF00069.25 EGG11628.1 - 4.7e-47 160.6 0.0 6.6e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11628.1 - 6.1e-30 104.4 0.0 9.2e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG11628.1 - 0.00031 19.7 0.0 0.00053 18.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGG11628.1 - 0.00095 18.6 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 EGG11628.1 - 0.0075 15.3 0.3 0.011 14.8 0.3 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 EGG11628.1 - 0.13 12.2 0.0 0.97 9.3 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Med15 PF09606.10 EGG11630.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.2 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DNA_topoisoIV PF00521.20 EGG11633.1 - 1.7e-130 435.7 0.1 8e-130 433.5 0.0 2.0 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EGG11633.1 - 1.3e-52 177.4 3.2 4e-52 175.9 3.2 1.9 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EGG11633.1 - 4.6e-27 94.6 0.4 1.1e-26 93.4 0.4 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EGG11633.1 - 3.4e-14 53.3 0.6 1.9e-13 50.9 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EGG11633.1 - 1e-07 32.1 0.0 5e-07 29.9 0.0 2.2 1 0 0 1 1 1 1 Toprim domain Mitofilin PF09731.9 EGG11633.1 - 1.6 7.5 17.0 0.19 10.5 11.5 2.0 2 0 0 2 2 2 0 Mitochondrial inner membrane protein DTHCT PF08070.11 EGG11634.1 - 0.64 10.8 48.1 0.81 10.5 6.5 3.8 1 1 2 3 3 3 0 DTHCT (NUC029) region DUF3123 PF11321.8 EGG11634.1 - 5.8 7.6 7.6 2.1 9.1 4.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3123) GRAM PF02893.20 EGG11635.1 - 1.9e-27 95.4 0.0 2.8e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 GRAM domain TatD_DNase PF01026.21 EGG11635.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 TatD related DNase NTF2 PF02136.20 EGG11636.1 - 8.3e-11 42.5 0.3 1.1e-08 35.6 0.1 2.1 2 0 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EGG11636.1 - 1.2e-06 28.6 0.1 1.9e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DUF16 PF01519.16 EGG11638.1 - 0.04 14.4 1.1 0.04 14.4 1.1 2.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 Tristanin_u2 PF16638.5 EGG11638.1 - 8.6 7.2 10.8 2.1 9.2 5.7 2.4 2 1 1 3 3 3 0 Unstructured region on methyltransferase between zinc-fingers DUF4440 PF14534.6 EGG11639.1 - 0.022 15.2 0.0 0.029 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) MOR2-PAG1_C PF14225.6 EGG11639.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 Cell morphogenesis C-terminal Glyco_tran_28_C PF04101.16 EGG11640.1 - 2.5e-12 47.1 0.1 3.7e-12 46.6 0.1 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Octopine_DH PF02317.17 EGG11641.1 - 4.4e-22 78.8 0.0 6e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain WD40 PF00400.32 EGG11642.1 - 3.8e-32 109.8 18.0 2.8e-05 24.8 0.1 10.8 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG11642.1 - 2.5e-05 24.5 0.1 33 4.8 0.0 6.1 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 EGG11642.1 - 0.059 12.6 0.0 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Hairy_orange PF07527.13 EGG11646.1 - 0.033 14.4 0.1 0.033 14.4 0.1 1.9 2 0 0 2 2 2 0 Hairy Orange Apolipoprotein PF01442.18 EGG11651.1 - 0.057 13.3 1.6 0.58 10.0 0.3 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Focal_AT PF03623.13 EGG11651.1 - 0.14 12.2 1.5 3.6 7.6 0.5 2.5 2 0 0 2 2 2 0 Focal adhesion targeting region LXG PF04740.12 EGG11651.1 - 0.16 11.7 1.0 0.31 10.7 1.0 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily Baculo_PEP_C PF04513.12 EGG11651.1 - 0.26 11.3 2.4 0.58 10.2 2.4 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 EGG11651.1 - 2.2 8.3 4.5 14 5.7 0.5 2.6 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Polysacc_deac_1 PF01522.21 EGG11652.1 - 2.5e-25 88.8 0.3 4e-25 88.1 0.1 1.4 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 EGG11652.1 - 0.025 14.3 0.3 0.033 13.8 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) NAR PF16251.5 EGG11652.1 - 0.035 14.8 0.1 0.076 13.7 0.1 1.5 1 0 0 1 1 1 0 Nucleic acid-binding domain (NAR) TspO_MBR PF03073.15 EGG11653.1 - 3.6e-47 159.8 9.4 4.1e-47 159.6 9.4 1.0 1 0 0 1 1 1 1 TspO/MBR family Ninjurin PF04923.12 EGG11653.1 - 0.06 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Ninjurin RE_EcoO109I PF14511.6 EGG11656.1 - 0.12 12.0 0.7 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Type II restriction endonuclease EcoO109I Glyco_hydro_31 PF01055.26 EGG11657.1 - 1.4e-101 340.9 2.0 2.2e-98 330.3 1.6 3.2 2 1 0 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EGG11657.1 - 1e-27 96.6 0.1 2e-27 95.7 0.1 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EGG11657.1 - 4.2e-12 46.2 0.1 1.3e-11 44.6 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like TPR_10 PF13374.6 EGG11658.1 - 0.031 14.1 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGG11658.1 - 0.06 13.1 0.0 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 TPR repeat FMO-like PF00743.19 EGG11659.1 - 1.9e-28 99.2 0.0 1.3e-20 73.3 0.0 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EGG11659.1 - 1.3e-09 37.6 0.0 3.4e-07 29.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EGG11659.1 - 1.5e-05 24.4 0.0 0.00053 19.3 0.0 2.7 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.6 EGG11659.1 - 3.6e-05 23.8 0.0 0.012 15.6 0.0 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGG11659.1 - 0.00025 21.2 0.0 0.00067 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG11659.1 - 0.0017 17.6 0.0 0.0061 15.8 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG11659.1 - 0.0028 17.0 0.1 20 4.3 0.0 3.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF5349 PF17298.2 EGG11660.1 - 2.9 7.6 8.2 6 6.5 8.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Melibiase_2 PF16499.5 EGG11661.1 - 0.0051 16.0 0.0 0.0059 15.8 0.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Tafi-CsgC PF10610.9 EGG11661.1 - 0.071 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Thin aggregative fimbriae synthesis protein FAA_hydrolase PF01557.18 EGG11665.1 - 1.1e-55 188.7 0.0 1.3e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family STE3 PF02076.15 EGG11666.1 - 3.4e-60 203.7 19.7 4.1e-60 203.5 19.7 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF3530 PF12048.8 EGG11668.1 - 0.31 10.4 3.1 0.61 9.4 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Myc_N PF01056.18 EGG11668.1 - 2 8.2 13.2 0.22 11.4 5.0 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Cu-oxidase_3 PF07732.15 EGG11669.1 - 1.3e-40 138.1 4.1 9.4e-40 135.3 1.3 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EGG11669.1 - 5.9e-31 107.7 0.3 1.7e-26 93.2 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG11669.1 - 3.4e-28 98.1 6.7 4.7e-25 87.9 0.3 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGG11670.1 - 1.3e-41 141.3 1.2 5.3e-40 136.1 0.2 2.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG11670.1 - 2.9e-30 104.8 3.2 6.1e-26 90.8 0.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGG11670.1 - 3e-25 89.2 0.1 3e-24 85.9 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase YrhC PF14143.6 EGG11670.1 - 0.0084 16.2 0.1 0.028 14.5 0.1 1.8 2 0 0 2 2 2 1 YrhC-like protein Cu-oxidase_3 PF07732.15 EGG11671.1 - 2.9e-40 137.0 1.3 8.2e-40 135.5 0.1 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EGG11671.1 - 1.3e-29 103.4 0.2 2.5e-25 89.5 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG11671.1 - 7.5e-29 100.2 4.6 9.5e-26 90.2 0.2 2.8 2 1 0 2 2 2 2 Multicopper oxidase polyprenyl_synt PF00348.17 EGG11672.1 - 5e-94 314.1 0.0 6.6e-94 313.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase LMSTEN PF07988.12 EGG11672.1 - 0.057 12.9 0.2 0.13 11.7 0.2 1.6 1 0 0 1 1 1 0 LMSTEN motif Lipase_3 PF01764.25 EGG11673.1 - 9.5e-12 45.0 0.0 1.9e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGG11673.1 - 0.0029 18.3 0.3 0.02 15.5 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ribosomal_L9_N PF01281.19 EGG11674.1 - 7.7e-08 31.8 0.0 1.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Pkinase PF00069.25 EGG11675.1 - 6.3e-59 199.5 0.0 8.8e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11675.1 - 4e-28 98.4 0.0 6.4e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG11675.1 - 4.5e-06 26.2 0.1 5.5e-05 22.6 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EGG11675.1 - 0.0038 16.2 0.0 0.013 14.4 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGG11675.1 - 0.012 15.6 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA_12 PF13087.6 EGG11677.1 - 4.5e-62 209.2 0.0 5.7e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGG11677.1 - 3.5e-33 115.5 0.1 5e-33 115.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGG11677.1 - 7.5e-06 25.9 0.0 0.021 14.5 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EGG11677.1 - 0.047 13.4 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 EGG11677.1 - 0.077 12.8 0.0 0.35 10.7 0.0 2.1 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain GET2 PF08690.10 EGG11678.1 - 4.6 6.8 10.6 5 6.7 10.6 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 NTP_transferase PF00483.23 EGG11679.1 - 4.5e-27 95.2 0.0 5.9e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EGG11679.1 - 5.4e-08 32.3 6.6 1.2e-06 28.0 0.4 3.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EGG11679.1 - 3.2e-05 24.3 0.0 5.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EGG11679.1 - 0.12 11.3 0.2 0.25 10.2 0.1 1.7 2 0 0 2 2 2 0 L-fucokinase Formyl_trans_N PF00551.19 EGG11680.1 - 1.7e-12 47.4 0.0 3.3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase FA_desaturase PF00487.24 EGG11681.1 - 1.7e-09 37.9 24.5 1.7e-09 37.9 24.5 1.8 2 1 0 2 2 2 1 Fatty acid desaturase SH3_1 PF00018.28 EGG11682.1 - 3.1e-10 39.5 0.0 5.7e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG11682.1 - 1.7e-08 34.0 0.0 3.2e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGG11682.1 - 1.8e-08 34.1 0.0 3.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_4 PF06347.13 EGG11682.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_3 PF08239.11 EGG11682.1 - 0.087 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Glucan_synthase PF02364.15 EGG11683.1 - 5.4e-46 157.2 2.5 5.4e-30 104.3 0.0 3.8 2 1 1 3 3 3 3 1,3-beta-glucan synthase component Glucan_synthase PF02364.15 EGG11684.1 - 3e-34 118.3 9.0 8.6e-16 57.3 0.6 3.0 1 1 2 3 3 3 3 1,3-beta-glucan synthase component Zn_clus PF00172.18 EGG11687.1 - 0.51 10.5 5.7 5.9 7.1 0.2 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF713 PF05218.14 EGG11691.1 - 0.0037 17.0 1.4 0.0045 16.7 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF713) AAA_15 PF13175.6 EGG11691.1 - 0.015 15.0 0.7 0.017 14.8 0.7 1.0 1 0 0 1 1 1 0 AAA ATPase domain GSH_synthase PF03199.15 EGG11691.1 - 0.078 13.4 0.1 0.1 13.0 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic glutathione synthase DAGK_cat PF00781.24 EGG11691.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain CLZ PF16526.5 EGG11691.1 - 0.13 12.6 3.2 0.26 11.7 1.1 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Enkurin PF13864.6 EGG11691.1 - 0.14 12.6 3.2 0.3 11.5 3.2 1.6 1 1 0 1 1 1 0 Calmodulin-binding CCDC-167 PF15188.6 EGG11691.1 - 0.22 11.9 4.1 0.66 10.4 4.1 1.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Fmp27_WPPW PF10359.9 EGG11691.1 - 0.35 9.7 3.5 0.42 9.4 3.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Cep57_CLD_2 PF14197.6 EGG11691.1 - 0.39 10.8 4.3 0.87 9.7 4.3 1.6 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Uso1_p115_C PF04871.13 EGG11691.1 - 0.49 10.8 7.7 0.67 10.3 7.7 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region FlaC_arch PF05377.11 EGG11691.1 - 0.66 10.4 3.5 12 6.4 0.5 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.11 EGG11691.1 - 0.87 10.2 5.3 0.58 10.7 3.5 1.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Val_tRNA-synt_C PF10458.9 EGG11691.1 - 2.5 8.5 7.5 24 5.3 0.2 3.4 3 1 1 4 4 4 0 Valyl tRNA synthetase tRNA binding arm DUF2508 PF10704.9 EGG11691.1 - 3.7 7.8 6.5 2.5 8.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) SKA2 PF16740.5 EGG11692.1 - 0.0018 18.0 4.1 0.0027 17.5 4.1 1.4 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 RasGAP_C PF03836.15 EGG11692.1 - 0.022 14.9 4.4 0.03 14.5 4.4 1.3 1 0 0 1 1 1 0 RasGAP C-terminus Spc7 PF08317.11 EGG11692.1 - 0.023 13.6 8.9 0.028 13.3 8.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein COG5 PF10392.9 EGG11692.1 - 0.025 14.8 2.0 0.046 13.9 2.0 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 SseC PF04888.12 EGG11692.1 - 0.034 13.7 3.7 0.04 13.5 3.7 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family FapA PF03961.13 EGG11692.1 - 0.035 12.7 3.7 0.04 12.5 3.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 EGG11692.1 - 0.041 14.3 9.7 0.05 14.0 9.7 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Bacillus_HBL PF05791.11 EGG11692.1 - 0.049 13.5 7.2 0.082 12.7 3.2 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) KELK PF15796.5 EGG11692.1 - 0.05 14.1 4.8 0.05 14.1 3.4 1.8 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AMH_N PF04709.12 EGG11692.1 - 0.057 12.3 2.8 0.073 12.0 2.8 1.2 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region ING PF12998.7 EGG11692.1 - 0.057 14.0 5.9 0.044 14.4 3.7 1.8 1 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Pro-NT_NN PF07421.11 EGG11692.1 - 0.06 13.6 5.8 0.068 13.4 5.8 1.1 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor TMPIT PF07851.13 EGG11692.1 - 0.12 11.6 4.0 0.15 11.3 4.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Surfac_D-trimer PF09006.11 EGG11692.1 - 0.13 12.1 0.1 3.1 7.8 0.0 2.3 1 1 1 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Phe_hydrox_dim PF07976.12 EGG11692.1 - 0.19 11.7 0.5 0.72 9.9 0.5 1.8 1 1 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain DUF2576 PF10845.8 EGG11692.1 - 0.19 11.3 0.6 15 5.3 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2576) Jnk-SapK_ap_N PF09744.9 EGG11692.1 - 0.22 11.7 11.0 0.29 11.4 11.0 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DivIC PF04977.15 EGG11692.1 - 0.23 11.3 4.4 0.096 12.5 1.2 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF3958 PF13125.6 EGG11692.1 - 0.28 11.4 9.0 0.15 12.2 7.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) GrpE PF01025.19 EGG11692.1 - 0.36 10.5 6.0 0.32 10.6 5.2 1.3 1 1 0 1 1 1 0 GrpE APG6_N PF17675.1 EGG11692.1 - 0.42 11.1 9.7 0.66 10.5 9.7 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 EGG11692.1 - 0.73 9.4 5.6 0.87 9.1 5.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF16 PF01519.16 EGG11692.1 - 9.6 6.8 9.1 12 6.4 7.0 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 PABP PF00658.18 EGG11693.1 - 1e-08 35.2 0.1 1.2e-08 35.0 0.1 1.0 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain PTCB-BRCT PF12738.7 EGG11694.1 - 3.8e-11 42.8 0.0 4e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 twin BRCT domain BRCT PF00533.26 EGG11694.1 - 3.4e-06 27.4 0.0 0.00056 20.2 0.0 2.6 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain FKBP_N_2 PF18023.1 EGG11696.1 - 0.06 13.4 0.1 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 BDBT FKBP like N-terminal DnaJ PF00226.31 EGG11700.1 - 1.6e-12 47.3 0.2 3.4e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 DnaJ domain ADAM_spacer1 PF05986.14 EGG11700.1 - 0.025 14.6 0.0 0.067 13.2 0.0 1.7 1 1 1 2 2 2 0 ADAM-TS Spacer 1 DinB_2 PF12867.7 EGG11701.1 - 4.4e-06 27.2 1.5 5.9e-06 26.8 1.5 1.2 1 0 0 1 1 1 1 DinB superfamily SNF2_N PF00176.23 EGG11702.1 - 5.3e-73 245.7 0.8 1.5e-72 244.2 0.8 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EGG11702.1 - 1.8e-40 137.5 3.9 1.8e-40 137.5 3.9 2.5 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 EGG11702.1 - 1.3e-21 77.4 2.2 1.3e-21 77.4 2.2 3.9 4 0 0 4 4 2 1 HAND Helicase_C PF00271.31 EGG11702.1 - 7.9e-19 68.1 0.0 1e-17 64.5 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG11702.1 - 5.5e-09 36.3 0.0 5.5e-09 36.3 0.0 3.8 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGG11702.1 - 3.7e-06 26.3 1.2 6.3e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EGG11702.1 - 0.00045 20.0 0.0 0.0014 18.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1086 PF06461.11 EGG11702.1 - 0.00087 19.2 0.1 0.00087 19.2 0.1 2.2 2 1 0 2 2 2 1 Domain of Unknown Function (DUF1086) ERCC3_RAD25_C PF16203.5 EGG11702.1 - 0.001 18.3 0.2 0.001 18.3 0.2 2.9 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase Myb_DNA-binding PF00249.31 EGG11702.1 - 0.0036 17.5 7.8 0.089 13.0 0.1 3.0 3 0 0 3 3 2 2 Myb-like DNA-binding domain DBINO PF13892.6 EGG11702.1 - 0.0075 16.6 0.5 0.0075 16.6 0.5 4.7 6 0 0 6 6 4 1 DNA-binding domain AAA_14 PF13173.6 EGG11702.1 - 0.019 15.0 0.0 0.072 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.15 EGG11702.1 - 0.076 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 AAA_22 PF13401.6 EGG11702.1 - 0.098 12.9 0.2 0.76 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Thymidylat_synt PF00303.19 EGG11703.1 - 1.1e-106 355.9 0.0 1.2e-106 355.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Vps39_1 PF10366.9 EGG11705.1 - 6.1e-28 97.3 0.1 6.1e-28 97.3 0.1 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EGG11705.1 - 1.2e-18 67.6 0.2 3.5e-18 66.1 0.2 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 EGG11705.1 - 1.5e-06 28.2 9.5 0.00047 20.0 1.3 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS APAF1_C PF17908.1 EGG11705.1 - 0.0026 17.8 2.6 0.54 10.3 0.1 3.1 2 0 0 2 2 2 2 APAF-1 helical domain TPR_8 PF13181.6 EGG11705.1 - 3.7 8.0 8.6 13 6.3 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3237 PF11578.8 EGG11706.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) ATP-synt_C PF00137.21 EGG11709.1 - 1.8e-25 89.0 21.7 1e-13 51.4 8.9 2.4 2 0 0 2 2 2 2 ATP synthase subunit C AA_permease_2 PF13520.6 EGG11710.1 - 0.0029 16.5 8.1 0.0038 16.1 8.1 1.2 1 0 0 1 1 1 1 Amino acid permease POX PF07526.11 EGG11710.1 - 0.012 16.2 2.0 0.018 15.6 2.0 1.2 1 0 0 1 1 1 0 Associated with HOX CCDC24 PF15669.5 EGG11710.1 - 0.2 11.5 2.8 0.29 11.0 2.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family QLQ PF08880.11 EGG11712.1 - 0.058 13.2 0.2 0.16 11.7 0.2 1.8 1 0 0 1 1 1 0 QLQ DUF2470 PF10615.9 EGG11713.1 - 0.18 12.4 0.3 10 6.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2470) Glycos_transf_3 PF00591.21 EGG11714.1 - 1.1e-72 244.7 0.0 1.2e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Retrotran_gag_3 PF14244.6 EGG11716.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF948 PF06103.11 EGG11719.1 - 0.00071 19.8 3.0 0.0014 18.9 3.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 EGG11719.1 - 0.0035 17.8 2.1 0.0085 16.5 2.1 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein T3SSipB PF16535.5 EGG11719.1 - 0.024 15.1 0.0 0.038 14.5 0.0 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB PMC2NT PF08066.12 EGG11719.1 - 0.056 14.1 1.4 0.32 11.7 1.5 2.1 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DUF1664 PF07889.12 EGG11719.1 - 0.43 10.6 2.4 0.56 10.3 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Rhodanese PF00581.20 EGG11720.1 - 2e-08 34.7 0.0 2.7e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain ABM PF03992.16 EGG11722.1 - 8.8e-13 48.2 0.0 1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase HSP20 PF00011.21 EGG11723.1 - 6e-09 36.0 0.0 6.2e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG11723.1 - 0.0002 20.8 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PigN PF04987.14 EGG11726.1 - 6.3e-138 460.4 33.6 8.3e-138 460.1 33.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EGG11726.1 - 2.5e-08 33.9 2.8 1.9e-07 31.0 0.2 2.4 2 1 1 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGG11726.1 - 0.00039 19.9 0.0 0.001 18.6 0.0 1.6 2 0 0 2 2 2 1 Sulfatase UreD PF01774.17 EGG11727.1 - 7.1e-46 156.8 0.0 9.2e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DUF5004 PF16395.5 EGG11727.1 - 0.14 12.1 1.4 0.4 10.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5004) TPR_2 PF07719.17 EGG11728.1 - 1.8e-19 68.2 6.1 7.5e-07 28.8 0.2 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGG11728.1 - 9.6e-19 66.4 5.6 7e-09 35.1 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGG11728.1 - 5.1e-12 45.6 1.1 5.1e-05 23.8 0.0 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG11728.1 - 5.4e-12 45.2 4.5 1.1e-06 28.1 0.1 4.3 3 1 2 5 5 5 3 TPR repeat TPR_17 PF13431.6 EGG11728.1 - 5.6e-12 45.2 0.7 0.0067 16.7 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG11728.1 - 1.1e-10 40.9 4.0 2e-05 24.4 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG11728.1 - 1.6e-09 38.3 0.3 7.8e-06 26.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG11728.1 - 6e-07 29.9 0.2 0.04 14.4 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG11728.1 - 6.3e-07 29.6 0.1 0.042 14.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGG11728.1 - 5.5e-05 23.2 0.1 0.00095 19.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG11728.1 - 0.0004 20.2 0.0 0.027 14.5 0.0 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG11728.1 - 0.0023 18.4 0.1 0.49 11.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGG11728.1 - 0.025 14.4 0.5 0.12 12.3 0.2 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3622 PF12286.8 EGG11729.1 - 0.06 13.7 0.1 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3622) MT-A70 PF05063.14 EGG11730.1 - 8.4e-56 188.6 0.0 1.8e-55 187.5 0.0 1.5 1 1 0 1 1 1 1 MT-A70 CoaE PF01121.20 EGG11732.1 - 8.7e-56 188.4 0.0 1e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EGG11732.1 - 1.9e-05 25.2 0.1 0.00011 22.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EGG11732.1 - 0.042 14.0 0.1 4.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase PMP22_Claudin PF00822.20 EGG11732.1 - 0.045 13.6 0.3 7.9 6.3 0.1 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family AAA_33 PF13671.6 EGG11732.1 - 0.047 13.9 0.0 0.1 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain Protoglobin PF11563.8 EGG11735.1 - 1e-05 25.5 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protoglobin CxC6 PF18721.1 EGG11737.1 - 9.2e-20 70.7 2.3 2.1e-19 69.5 2.3 1.7 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 EGG11737.1 - 2.2e-17 63.2 2.3 4.8e-17 62.1 2.3 1.6 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Neprosin PF03080.15 EGG11737.1 - 0.24 10.7 0.1 0.39 10.0 0.1 1.3 1 0 0 1 1 1 0 Neprosin ParA PF10609.9 EGG11738.1 - 2.1e-83 279.6 1.3 2.6e-83 279.3 1.3 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGG11738.1 - 3.2e-13 49.9 0.0 1e-12 48.2 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGG11738.1 - 5.5e-08 32.9 1.4 2e-05 24.6 0.2 2.3 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 EGG11738.1 - 6.9e-05 22.2 2.8 0.00038 19.7 0.4 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 EGG11738.1 - 7.9e-05 22.1 0.8 0.00019 20.8 0.1 1.8 2 0 0 2 2 2 1 ATPase MipZ AAA_26 PF13500.6 EGG11738.1 - 0.002 18.0 1.3 0.24 11.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain zf-ZPR1 PF03367.13 EGG11738.1 - 0.0052 16.7 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 ZPR1 zinc-finger domain Fer4_NifH PF00142.18 EGG11738.1 - 0.016 14.6 0.0 0.058 12.8 0.1 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 EGG11738.1 - 0.11 12.0 0.3 0.78 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGG11738.1 - 0.16 11.2 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Fe-S_biosyn PF01521.20 EGG11739.1 - 9.8e-14 51.5 0.0 1.6e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis ATXN-1_C PF12547.8 EGG11739.1 - 3.5 8.0 10.1 0.53 10.7 5.9 1.7 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator PS_Dcarbxylase PF02666.15 EGG11740.1 - 6.5e-51 172.7 0.0 1e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EGG11740.1 - 1.6e-27 95.8 0.0 8.3e-16 58.2 0.0 3.1 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.6 EGG11740.1 - 0.0013 19.2 0.1 0.013 16.0 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGG11740.1 - 0.021 14.7 4.5 0.045 13.7 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain EF-hand_5 PF13202.6 EGG11740.1 - 0.024 14.1 0.2 0.11 12.1 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_1 PF00036.32 EGG11740.1 - 0.068 12.7 0.0 0.068 12.7 0.0 3.2 4 0 0 4 4 4 0 EF hand SDA1 PF05285.12 EGG11740.1 - 4.6 6.6 11.3 9.2 5.6 11.3 1.4 1 0 0 1 1 1 0 SDA1 tRNA-synt_2d PF01409.20 EGG11742.1 - 1.9e-45 155.3 0.3 1.4e-25 90.2 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EGG11742.1 - 2.7e-24 85.4 0.0 6.6e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain NKWYS PF10364.9 EGG11742.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein MMM1 PF10296.9 EGG11743.1 - 4.4e-08 32.6 0.1 1.4e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 AAR2 PF05282.11 EGG11744.1 - 1.7e-55 188.9 2.6 1.9e-55 188.7 2.6 1.0 1 0 0 1 1 1 1 AAR2 protein Mo25 PF08569.11 EGG11745.1 - 1.1e-56 192.7 10.2 1.2e-56 192.5 10.2 1.0 1 0 0 1 1 1 1 Mo25-like DUF2367 PF10164.9 EGG11747.1 - 0.11 13.0 0.3 0.42 11.1 0.3 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) DDE_Tnp_IS240 PF13610.6 EGG11747.1 - 0.16 12.2 0.1 0.32 11.2 0.1 1.4 1 0 0 1 1 1 0 DDE domain zf-CCHC PF00098.23 EGG11750.1 - 0.0096 16.0 1.9 0.022 14.9 1.9 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EGG11750.1 - 0.034 14.4 0.0 0.076 13.3 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Ribosomal_S3_C PF00189.20 EGG11751.1 - 4e-23 81.7 0.3 1.9e-22 79.5 0.1 2.1 3 0 0 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EGG11751.1 - 4.1e-14 52.2 0.1 6.9e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 EGG11751.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus UPF0181 PF03701.14 EGG11752.1 - 0.022 14.4 0.2 0.055 13.1 0.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Saw1 PF11561.8 EGG11752.1 - 0.025 14.1 2.1 0.042 13.4 2.1 1.4 1 0 0 1 1 1 0 Single strand annealing-weakened 1 DUF3734 PF12536.8 EGG11752.1 - 0.025 14.9 0.6 0.055 13.8 0.5 1.7 1 1 0 1 1 1 0 Patatin phospholipase Dicty_REP PF05086.12 EGG11753.1 - 0.43 8.5 3.6 0.5 8.3 3.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GRP PF07172.11 EGG11754.1 - 0.066 13.9 0.0 0.095 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycine rich protein family TTL PF03133.15 EGG11756.1 - 7.3e-60 202.6 0.5 9.9e-60 202.2 0.5 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGG11756.1 - 6.8e-06 25.5 0.0 7.5e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGG11756.1 - 0.0015 17.8 0.0 0.29 10.3 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RRF PF01765.19 EGG11756.1 - 0.03 14.3 0.8 0.03 14.3 0.8 1.7 2 0 0 2 2 2 0 Ribosome recycling factor BioT2 PF15368.6 EGG11757.1 - 0.093 12.7 1.1 0.11 12.4 1.1 1.1 1 0 0 1 1 1 0 Spermatogenesis family BioT2 Atrophin-1 PF03154.15 EGG11757.1 - 0.19 10.0 4.5 0.21 9.9 4.5 1.0 1 0 0 1 1 1 0 Atrophin-1 family Alpha_GJ PF03229.13 EGG11757.1 - 0.43 11.1 3.8 0.69 10.5 3.8 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J Hamartin PF04388.12 EGG11757.1 - 0.63 8.6 5.1 0.68 8.5 5.1 1.0 1 0 0 1 1 1 0 Hamartin protein COesterase PF00135.28 EGG11758.1 - 1.2e-64 219.1 0.0 1.9e-64 218.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family RseA_C PF03873.13 EGG11758.1 - 0.41 10.9 1.9 1.1 9.5 1.9 1.8 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain DUF963 PF06131.11 EGG11758.1 - 0.96 8.9 24.1 0.26 10.8 19.6 2.3 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF846 PF05832.12 EGG11760.1 - 5.3e-50 169.1 11.4 6.5e-50 168.8 11.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Pex14_N PF04695.13 EGG11760.1 - 0.035 14.8 0.1 0.063 13.9 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMCO5 PF14992.6 EGG11760.1 - 0.25 10.9 1.6 6.4 6.3 0.0 2.0 2 0 0 2 2 2 0 TMCO5 family DUF2070 PF09843.9 EGG11760.1 - 0.74 8.0 6.6 0.16 10.2 0.3 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) p450 PF00067.22 EGG11762.1 - 7.2e-52 176.7 0.1 9.5e-52 176.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EGG11763.1 - 1.4e-26 93.4 0.0 1.7e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11763.1 - 5.3e-13 48.9 0.0 7.4e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG11763.1 - 4.7e-05 22.3 0.0 6.1e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGG11763.1 - 6.7e-05 22.9 0.3 0.66 9.9 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG11763.1 - 0.19 10.6 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 EGG11765.1 - 4.1e-21 75.5 0.0 5.5e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11765.1 - 3.9e-11 42.7 0.0 5.2e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RGCC PF15151.6 EGG11766.1 - 0.2 11.9 3.4 9.1 6.5 2.9 2.1 2 0 0 2 2 2 0 Response gene to complement 32 protein family DnaJ PF00226.31 EGG11767.1 - 6.4e-17 61.4 0.1 2.4e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 EGG11767.1 - 0.0021 18.6 0.1 3 8.4 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat Dynactin_p22 PF07426.11 EGG11769.1 - 0.1 12.4 1.9 0.24 11.3 0.6 2.0 2 0 0 2 2 2 0 Dynactin subunit p22 CD24 PF14984.6 EGG11770.1 - 0.21 11.8 5.6 29 5.0 0.0 4.0 4 0 0 4 4 4 0 CD24 protein JmjC PF02373.22 EGG11771.1 - 3.8e-12 46.6 1.6 9.2e-12 45.4 0.1 2.6 2 0 0 2 2 2 1 JmjC domain, hydroxylase C1_1 PF00130.22 EGG11771.1 - 0.33 10.9 3.6 0.77 9.7 3.6 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ExbD PF02472.16 EGG11771.1 - 4.7 7.4 5.7 3.6 7.8 1.6 2.7 1 1 1 2 2 2 0 Biopolymer transport protein ExbD/TolR Hap4_Hap_bind PF10297.9 EGG11772.1 - 0.00094 19.2 6.1 0.0031 17.6 6.1 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 GAS PF13851.6 EGG11772.1 - 0.002 17.5 3.5 0.0033 16.8 3.5 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TSC22 PF01166.18 EGG11772.1 - 0.0049 17.2 1.3 0.013 15.8 0.3 2.3 1 1 1 2 2 2 1 TSC-22/dip/bun family Tho2 PF11262.8 EGG11772.1 - 0.011 15.0 0.6 0.017 14.3 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Jnk-SapK_ap_N PF09744.9 EGG11772.1 - 0.052 13.8 4.6 0.096 12.9 4.6 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Sipho_Gp157 PF05565.11 EGG11772.1 - 0.056 13.4 0.9 0.13 12.3 0.6 1.7 2 0 0 2 2 2 0 Siphovirus Gp157 HAUS-augmin3 PF14932.6 EGG11772.1 - 0.11 12.0 3.7 0.18 11.4 3.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Fmp27_WPPW PF10359.9 EGG11772.1 - 0.19 10.5 3.2 0.28 10.0 3.2 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain bZIP_1 PF00170.21 EGG11772.1 - 0.54 10.4 8.3 1.3 9.1 2.8 2.3 1 1 1 2 2 2 0 bZIP transcription factor Fib_alpha PF08702.10 EGG11772.1 - 2.3 8.4 7.0 1 9.5 4.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_14 PF13173.6 EGG11773.1 - 0.075 13.1 0.1 0.26 11.3 0.1 1.9 1 0 0 1 1 1 0 AAA domain CLZ PF16526.5 EGG11773.1 - 0.14 12.6 0.4 0.73 10.2 0.1 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Nucleoside_tran PF01733.18 EGG11773.1 - 0.18 11.2 0.1 0.33 10.3 0.1 1.3 1 0 0 1 1 1 0 Nucleoside transporter HTH_21 PF13276.6 EGG11774.1 - 0.0018 18.3 2.8 0.0068 16.5 0.7 2.7 3 0 0 3 3 3 1 HTH-like domain Clr5 PF14420.6 EGG11774.1 - 0.021 15.1 0.0 5.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Clr5 domain HTH_32 PF13565.6 EGG11774.1 - 0.056 14.1 8.1 0.17 12.5 0.0 4.1 5 1 1 6 6 6 0 Homeodomain-like domain Fumble PF03630.14 EGG11776.1 - 5.6e-125 416.9 0.2 3.2e-123 411.1 0.2 2.8 1 1 0 1 1 1 1 Fumble Methyltransf_3 PF01596.17 EGG11777.1 - 5e-14 52.0 0.0 1.3e-13 50.6 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 EGG11777.1 - 0.025 14.3 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 EGG11777.1 - 0.031 15.3 0.0 0.1 13.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain ThiF PF00899.21 EGG11779.1 - 7.2e-12 45.2 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family Fibrillarin PF01269.17 EGG11779.1 - 2e-05 23.8 0.1 3.3e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Fibrillarin UBA_e1_thiolCys PF10585.9 EGG11779.1 - 0.00054 20.0 0.3 0.00083 19.4 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Methyltransf_3 PF01596.17 EGG11780.1 - 1.5e-30 106.0 0.0 2.9e-30 105.0 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGG11780.1 - 2.2e-07 31.8 0.0 5.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGG11780.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Abhydrolase_2 PF02230.16 EGG11781.1 - 5.8e-13 49.1 0.0 8.9e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase MFS_1 PF07690.16 EGG11782.1 - 3.6e-20 72.2 27.3 2.2e-12 46.6 1.0 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG11782.1 - 0.00037 19.5 0.6 0.00037 19.5 0.6 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3455 PF11937.8 EGG11783.1 - 6.8e-20 72.0 0.0 9.8e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) PAC3 PF10178.9 EGG11784.1 - 0.00096 19.3 0.1 0.11 12.7 0.0 2.7 3 0 0 3 3 3 2 Proteasome assembly chaperone 3 Cu-oxidase PF00394.22 EGG11786.1 - 2e-42 145.0 1.2 1.8e-36 125.7 0.4 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGG11786.1 - 7.3e-40 135.9 10.0 3.2e-36 124.1 0.2 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGG11786.1 - 1.8e-34 118.3 5.7 1.6e-30 105.6 0.8 3.5 3 1 0 3 3 3 2 Multicopper oxidase CxC6 PF18721.1 EGG11788.1 - 6.2e-21 74.4 0.9 6.2e-21 74.4 0.9 2.2 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 EGG11788.1 - 5.8e-08 32.8 0.1 1.7e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Asp PF00026.23 EGG11789.1 - 2.1e-44 152.2 3.9 1.1e-43 149.8 3.9 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG11789.1 - 3.1e-10 40.6 0.5 0.00018 21.8 0.0 2.9 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EGG11789.1 - 0.0042 17.6 0.1 1.4 9.6 0.0 3.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGG11789.1 - 0.019 15.6 3.2 0.48 11.1 0.2 3.2 4 0 0 4 4 4 0 Aspartyl protease zf-ISL3 PF14690.6 EGG11793.1 - 0.018 15.7 0.1 5.2 7.8 0.0 2.6 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-Mss51 PF13824.6 EGG11793.1 - 0.17 12.0 0.3 0.59 10.3 0.3 1.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 PP-binding PF00550.25 EGG11798.1 - 1.2e-14 54.4 0.2 1.7e-14 53.9 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EGG11798.1 - 7e-05 23.0 0.2 0.00011 22.4 0.2 1.3 1 0 0 1 1 1 1 Acyl-carrier PCI PF01399.27 EGG11799.1 - 7.7e-19 68.2 1.2 2e-18 66.9 0.7 2.0 2 0 0 2 2 2 1 PCI domain TPR_10 PF13374.6 EGG11799.1 - 0.02 14.7 0.1 29 4.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EGG11799.1 - 0.077 13.1 0.5 0.49 10.5 0.1 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain zf-C2H2 PF00096.26 EGG11800.1 - 0.2 12.2 10.3 1.5 9.4 0.5 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG11800.1 - 1.2 10.2 9.9 5.6 8.1 1.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_transf_8 PF01501.20 EGG11801.1 - 3e-18 66.3 0.3 4.2e-18 65.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGG11801.1 - 0.00071 19.0 0.2 0.0048 16.3 0.1 1.9 2 0 0 2 2 2 1 Mannosyltransferase putative XPB_DRD PF18458.1 EGG11801.1 - 0.013 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain Glyco_transf_24 PF18404.1 EGG11801.1 - 0.02 14.3 0.1 0.054 12.9 0.0 1.7 2 0 0 2 2 2 0 Glucosyltransferase 24 Nucleotid_trans PF03407.16 EGG11801.1 - 0.14 12.1 0.1 1 9.3 0.1 1.9 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase TFIIA PF03153.13 EGG11803.1 - 7.9e-05 22.8 16.0 0.002 18.2 5.0 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit F-box-like PF12937.7 EGG11805.1 - 0.052 13.5 1.3 0.19 11.7 0.0 2.6 3 1 0 3 3 3 0 F-box-like F-box PF00646.33 EGG11805.1 - 8.7 6.4 7.3 4.7 7.2 0.1 3.7 5 0 0 5 5 5 0 F-box domain GCM PF03615.15 EGG11806.1 - 0.14 12.0 0.7 0.38 10.6 0.7 1.7 1 0 0 1 1 1 0 GCM motif protein DASH_Hsk3 PF08227.11 EGG11809.1 - 0.057 13.8 6.0 0.12 12.8 6.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like Pro-kuma_activ PF09286.11 EGG11812.1 - 1.4e-30 106.4 0.0 2.4e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGG11812.1 - 1.3e-06 27.9 0.1 2e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Subtilase family WW_FCH_linker PF16623.5 EGG11812.1 - 0.072 13.8 0.2 0.26 12.1 0.2 2.0 1 0 0 1 1 1 0 Unstructured linker region between on GAS7 protein Barwin PF00967.17 EGG11813.1 - 3.9e-06 26.7 0.1 5.6e-06 26.2 0.1 1.3 1 1 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 EGG11813.1 - 3.4e-05 24.0 0.0 9.7e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Lytic transglycolase MFS_1 PF07690.16 EGG11815.1 - 8.2e-26 90.8 33.8 1.2e-23 83.6 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2678 PF10856.8 EGG11815.1 - 0.034 14.1 0.5 0.21 11.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Phage_holin_3_6 PF07332.11 EGG11815.1 - 5.7 7.0 12.7 7.6 6.6 3.7 3.2 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1666 PF07891.12 EGG11816.1 - 0.022 14.4 0.3 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1666) G-gamma PF00631.22 EGG11817.1 - 5.7e-24 83.9 0.0 6.5e-24 83.7 0.0 1.1 1 0 0 1 1 1 1 GGL domain DLP_helical PF18709.1 EGG11817.1 - 0.25 10.5 0.0 0.3 10.3 0.0 1.0 1 0 0 1 1 1 0 Dynamin-like helical domain V-ATPase_G PF03179.15 EGG11820.1 - 0.13 12.8 10.6 0.22 12.1 10.6 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit AP1AR PF15745.5 EGG11820.1 - 0.19 11.3 4.4 0.28 10.8 4.4 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DUF4874 PF16173.5 EGG11821.1 - 0.087 12.5 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) DUF1770 PF08589.10 EGG11822.1 - 0.0018 19.2 0.1 0.0018 19.2 0.1 1.7 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1770) CS PF04969.16 EGG11823.1 - 1.2e-07 32.6 0.3 1.2e-06 29.5 0.1 2.8 3 1 0 3 3 3 1 CS domain Cobalamin_bind PF01122.19 EGG11824.1 - 0.014 14.3 1.1 0.016 14.1 1.1 1.1 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein TbpB_C PF17483.2 EGG11824.1 - 0.02 15.2 2.5 0.026 14.9 2.5 1.1 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B Fib_alpha PF08702.10 EGG11824.1 - 0.046 13.9 9.8 0.052 13.7 9.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Stealth_CR4 PF17103.5 EGG11826.1 - 0.11 12.4 0.7 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 G-alpha PF00503.20 EGG11827.1 - 3.5e-08 33.0 0.0 3.5e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Myticin-prepro PF10690.9 EGG11829.1 - 0.017 15.4 2.5 0.017 15.4 2.5 1.5 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel PFK PF00365.20 EGG11830.1 - 1.1e-41 143.0 0.0 1.4e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase zf-CHCC PF10276.9 EGG11831.1 - 9.5e-19 67.2 2.1 1.9e-18 66.2 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger domain zf_C2H2_6 PF18450.1 EGG11831.1 - 0.076 12.7 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Zinc Finger domain DUF5305 PF17231.2 EGG11832.1 - 0.1 12.0 4.9 0.26 10.7 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF3781 PF12636.7 EGG11833.1 - 0.064 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) WD40 PF00400.32 EGG11834.1 - 1e-41 140.1 17.3 1.6e-07 31.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG11834.1 - 1.2e-18 67.1 0.0 0.0012 19.1 0.1 5.3 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG11834.1 - 0.00016 21.6 0.0 0.62 9.9 0.0 2.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGG11834.1 - 0.00036 20.0 0.0 0.0081 15.5 0.0 2.9 1 1 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 EGG11834.1 - 0.012 14.6 0.2 6.6 5.6 0.0 3.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EGG11834.1 - 0.025 14.1 0.1 0.23 11.0 0.1 2.1 1 1 0 1 1 1 0 PQQ-like domain Cytochrom_D1 PF02239.16 EGG11834.1 - 0.13 10.7 0.0 0.35 9.3 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain GPI-anchored PF10342.9 EGG11836.1 - 1.7e-12 47.9 2.2 1.7e-12 47.9 2.2 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PrpR_N PF06506.11 EGG11836.1 - 0.036 13.6 0.1 0.055 13.0 0.1 1.2 1 0 0 1 1 1 0 Propionate catabolism activator HA2 PF04408.23 EGG11837.1 - 9.1e-17 61.3 0.0 3.1e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGG11837.1 - 9.2e-13 48.5 0.0 2.2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 EGG11837.1 - 9.9e-12 45.4 0.0 0.00019 22.1 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 EGG11837.1 - 2.7e-05 24.0 0.0 5.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EGG11837.1 - 0.0053 17.1 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Dicer_dimer PF03368.14 EGG11837.1 - 0.013 15.6 0.0 0.057 13.6 0.0 2.1 1 0 0 1 1 1 0 Dicer dimerisation domain ResIII PF04851.15 EGG11837.1 - 0.037 14.0 0.1 0.17 11.9 0.0 2.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EGG11837.1 - 0.09 12.3 0.0 0.28 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGG11837.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Cellulase PF00150.18 EGG11838.1 - 6.4e-11 42.2 0.5 1e-10 41.5 0.1 1.6 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_53 PF07745.13 EGG11838.1 - 0.049 12.6 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 PUB PF09409.10 EGG11841.1 - 1.6e-13 50.4 1.3 5.4e-13 48.7 0.2 2.2 2 1 0 2 2 2 1 PUB domain HTH_27 PF13463.6 EGG11841.1 - 0.1 13.1 1.0 2.1 8.9 0.1 2.9 3 0 0 3 3 3 0 Winged helix DNA-binding domain DUF2229 PF09989.9 EGG11841.1 - 4 7.0 5.8 6.9 6.2 1.4 2.0 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Homoserine_dh PF00742.19 EGG11842.1 - 7.4e-51 172.5 0.0 1.4e-50 171.6 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EGG11842.1 - 2e-10 41.4 0.0 4.1e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 EGG11842.1 - 0.033 14.5 0.1 0.074 13.4 0.1 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GST_N_3 PF13417.6 EGG11843.1 - 1.3e-09 38.4 0.0 4.6e-09 36.5 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGG11843.1 - 2e-06 28.0 0.0 4.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGG11843.1 - 4.5e-06 26.9 0.0 1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGG11843.1 - 0.00015 21.7 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG11843.1 - 0.0095 16.1 0.0 0.036 14.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG11843.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sacchrp_dh_NADP PF03435.18 EGG11847.1 - 5.6e-13 49.3 0.0 1.1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TGT_C1 PF14809.6 EGG11847.1 - 0.096 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 C1 domain of tRNA-guanine transglycosylase dimerisation A_deaminase PF00962.22 EGG11848.1 - 5.5e-26 91.7 0.0 7.6e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 EGG11848.1 - 8.3e-05 22.0 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family PKD_3 PF16820.5 EGG11848.1 - 0.0037 17.0 0.1 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 PKD-like domain A_deaminase PF00962.22 EGG11849.1 - 6.7e-24 84.8 0.1 8.2e-24 84.5 0.1 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 EGG11849.1 - 4.1e-06 26.4 0.2 7.4e-06 25.5 0.2 1.4 1 1 0 1 1 1 1 Amidohydrolase family PKD_3 PF16820.5 EGG11849.1 - 0.012 15.3 0.0 0.035 13.8 0.0 1.8 1 0 0 1 1 1 0 PKD-like domain TP_methylase PF00590.20 EGG11849.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases NIF PF03031.18 EGG11850.1 - 0.055 13.2 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Vps5 PF09325.10 EGG11851.1 - 5e-05 23.0 0.4 0.0063 16.1 0.0 2.1 1 1 1 2 2 2 2 Vps5 C terminal like Rab_bind PF16704.5 EGG11851.1 - 0.015 15.3 0.1 0.026 14.5 0.1 1.4 1 0 0 1 1 1 0 Rab binding domain Allexi_40kDa PF05549.11 EGG11851.1 - 0.02 14.4 0.6 0.025 14.1 0.6 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Myb_DNA-bind_4 PF13837.6 EGG11853.1 - 0.0045 17.3 0.5 0.0097 16.3 0.5 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EGG11853.1 - 0.006 16.9 1.1 0.018 15.3 1.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like KIF1B PF12423.8 EGG11853.1 - 0.18 12.2 0.6 0.42 11.1 0.6 1.7 1 0 0 1 1 1 0 Kinesin protein 1B DUF573 PF04504.14 EGG11853.1 - 0.2 12.4 0.4 0.2 12.4 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Vps5 PF09325.10 EGG11853.1 - 8.7 5.8 9.5 1.7 8.1 5.3 2.1 2 1 0 2 2 2 0 Vps5 C terminal like Kelch_4 PF13418.6 EGG11854.1 - 2.6e-42 142.6 8.4 8.8e-08 32.0 0.1 6.1 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 EGG11854.1 - 3.7e-40 135.2 0.7 5.7e-06 25.8 0.0 6.1 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EGG11854.1 - 3.7e-34 115.9 5.6 5.5e-05 23.3 0.0 6.2 3 1 3 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EGG11854.1 - 1.4e-32 111.1 3.6 6.8e-06 25.9 0.2 6.1 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGG11854.1 - 4.3e-32 109.8 1.8 7.9e-06 26.0 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 EGG11854.1 - 4.6e-30 102.4 8.3 8.1e-05 22.4 0.0 6.2 6 0 0 6 6 6 6 Kelch motif RRM_1 PF00076.22 EGG11856.1 - 1.8e-16 59.7 0.0 2.2e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 EGG11857.1 - 1.1e-22 80.7 0.0 3.3e-13 49.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11857.1 - 1.1e-07 31.5 0.7 0.0014 18.0 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGG11857.1 - 0.0063 16.5 0.0 0.0076 16.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGG11857.1 - 0.082 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGG11857.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EGG11857.1 - 0.13 11.5 1.4 0.46 9.7 0.0 2.0 1 1 1 2 2 2 0 Kinase-like dUTPase PF00692.19 EGG11859.1 - 1.3e-28 99.3 0.0 1.6e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 dUTPase MAM33 PF02330.16 EGG11860.1 - 3.6e-61 206.8 4.2 4.2e-61 206.6 4.2 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Pkinase PF00069.25 EGG11861.1 - 1.3e-68 231.3 0.0 1.5e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11861.1 - 3e-33 115.2 0.1 1e-32 113.5 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG11861.1 - 0.0029 16.6 0.2 0.035 13.0 0.2 2.2 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGG11861.1 - 0.018 15.0 0.1 0.039 13.9 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG11861.1 - 0.034 13.5 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGG11861.1 - 0.036 13.4 0.1 0.061 12.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGG11861.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pox_Ag35 PF03286.14 EGG11862.1 - 0.064 13.0 3.0 0.13 12.0 3.0 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RFamide_26RFa PF11109.8 EGG11862.1 - 0.79 10.2 4.2 0.39 11.2 1.8 1.6 2 0 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 CBFB_NFYA PF02045.15 EGG11863.1 - 1.1e-25 90.0 5.1 1.6e-25 89.4 5.1 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B MAM33 PF02330.16 EGG11865.1 - 0.033 14.1 2.1 0.073 13.0 2.1 1.5 1 0 0 1 1 1 0 Mitochondrial glycoprotein FAM177 PF14774.6 EGG11865.1 - 2.3 8.6 5.9 0.47 10.8 2.1 1.7 2 0 0 2 2 2 0 FAM177 family Serglycin PF04360.12 EGG11865.1 - 2.5 8.1 8.9 9.6 6.1 8.9 2.1 1 0 0 1 1 1 0 Serglycin EVC2_like PF12297.8 EGG11868.1 - 0.046 12.4 0.1 0.084 11.6 0.1 1.4 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF202 PF02656.15 EGG11868.1 - 0.16 12.4 1.5 1.2 9.6 1.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) IBR PF01485.21 EGG11869.1 - 7.5e-16 58.1 41.1 1.1e-10 41.6 6.6 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain DUF5344 PF17279.2 EGG11869.1 - 0.19 12.4 2.1 15 6.3 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5344) PSCyt3 PF07627.11 EGG11869.1 - 4.1 7.7 7.0 44 4.4 3.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1588) Sacchrp_dh_NADP PF03435.18 EGG11870.1 - 2.8e-12 47.0 0.0 4.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain SpoIIIAC PF06686.11 EGG11870.1 - 0.069 13.3 0.3 0.2 11.9 0.3 1.8 1 0 0 1 1 1 0 Stage III sporulation protein AC/AD protein family Sacchrp_dh_NADP PF03435.18 EGG11873.1 - 1.2e-08 35.2 0.0 2.4e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 EGG11874.1 - 2.6e-68 230.3 0.0 5.1e-68 229.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG11874.1 - 2.8e-36 125.1 0.0 4.3e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EGG11874.1 - 4e-25 87.8 0.9 9.7e-15 54.5 0.3 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EGG11874.1 - 0.00018 21.0 0.0 1.9 7.7 0.0 3.2 2 1 1 3 3 3 3 Kinase-like Vps16_N PF04841.13 EGG11876.1 - 1.5e-69 234.7 0.0 3.3e-69 233.6 0.0 1.5 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EGG11876.1 - 3.5e-54 184.0 2.6 1.9e-53 181.6 2.6 2.0 1 1 0 1 1 1 1 Vps16, C-terminal region DUF1995 PF09353.10 EGG11878.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) SPA PF08616.10 EGG11879.1 - 5e-35 119.9 0.0 1.6e-34 118.3 0.0 1.9 2 0 0 2 2 2 1 Stabilization of polarity axis Afi1 PF07792.12 EGG11879.1 - 1.5e-27 96.7 1.3 2.6e-27 95.9 1.3 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 EGG11879.1 - 1.6e-09 37.0 0.0 8.1e-05 21.5 0.0 3.3 3 1 0 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.9 EGG11879.1 - 0.001 18.7 0.0 0.23 11.0 0.0 2.7 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Suf PF05843.14 EGG11884.1 - 0.013 15.5 1.1 0.025 14.6 0.8 1.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) JAKMIP_CC3 PF16034.5 EGG11884.1 - 0.014 15.4 2.8 0.026 14.5 2.8 1.4 1 0 0 1 1 1 0 JAKMIP CC3 domain Sec23_trunk PF04811.15 EGG11885.1 - 2.4e-71 240.1 0.0 4.1e-71 239.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGG11885.1 - 1.1e-24 86.2 0.1 4.1e-24 84.4 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGG11885.1 - 1.2e-17 64.4 0.0 6.4e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGG11885.1 - 1.2e-15 57.3 5.8 2.3e-15 56.4 5.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGG11885.1 - 2.4e-08 33.7 0.0 4.9e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.26 EGG11885.1 - 8.5e-05 22.6 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 WW domain Vps36-NZF-N PF16988.5 EGG11885.1 - 0.0085 15.5 0.2 0.019 14.4 0.2 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain WD40 PF00400.32 EGG11886.1 - 5.9e-58 191.5 27.6 1.3e-10 41.7 0.1 8.0 8 0 0 8 8 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EGG11886.1 - 9e-24 83.6 9.1 1.3e-23 83.1 9.1 1.2 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EGG11886.1 - 3.5e-22 78.5 0.0 0.00051 20.3 0.0 6.4 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG11886.1 - 6.6e-12 45.0 0.1 0.035 13.1 0.0 5.8 4 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGG11886.1 - 2.5e-08 33.6 1.5 0.2 11.6 0.0 6.2 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EGG11886.1 - 2.7e-07 30.2 0.0 0.13 11.6 0.0 4.1 5 0 0 5 5 4 2 WD40-like domain Nup160 PF11715.8 EGG11886.1 - 9.9e-06 24.5 0.4 0.024 13.3 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 EGG11886.1 - 1.5e-05 24.5 0.5 0.73 9.1 0.0 4.1 2 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 EGG11886.1 - 0.0008 17.8 0.0 0.57 8.4 0.0 3.4 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Spc7 PF08317.11 EGG11886.1 - 0.0038 16.2 5.9 0.005 15.8 5.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF5122 PF17164.4 EGG11886.1 - 0.006 16.8 1.5 24 5.3 0.1 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller DUF4763 PF15960.5 EGG11886.1 - 0.0061 15.9 1.3 0.0094 15.3 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) DUF724 PF05266.14 EGG11886.1 - 0.0096 15.8 1.3 0.015 15.2 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) DivIVA PF05103.13 EGG11886.1 - 0.01 15.9 1.4 0.016 15.3 1.4 1.2 1 0 0 1 1 1 0 DivIVA protein YabA PF06156.13 EGG11886.1 - 0.011 16.4 0.4 0.025 15.2 0.4 1.6 1 0 0 1 1 1 0 Initiation control protein YabA DegS PF05384.11 EGG11886.1 - 0.015 14.8 1.9 0.024 14.1 1.9 1.2 1 0 0 1 1 1 0 Sensor protein DegS DUF812 PF05667.11 EGG11886.1 - 0.015 14.2 3.1 0.022 13.7 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SHE3 PF17078.5 EGG11886.1 - 0.018 14.8 3.3 0.31 10.7 5.0 1.9 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 YscO PF07321.12 EGG11886.1 - 0.02 14.8 7.1 0.031 14.2 7.1 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO HALZ PF02183.18 EGG11886.1 - 0.021 15.0 6.3 0.65 10.3 0.2 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper ADIP PF11559.8 EGG11886.1 - 0.022 14.9 8.1 0.035 14.2 8.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cytochrom_D1 PF02239.16 EGG11886.1 - 0.031 12.8 0.3 2.9 6.3 0.0 2.5 2 1 0 2 2 2 0 Cytochrome D1 heme domain DUF4201 PF13870.6 EGG11886.1 - 0.038 13.7 4.9 0.059 13.1 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) nos_propeller PF18764.1 EGG11886.1 - 0.038 13.9 0.1 31 4.6 0.0 3.7 4 0 0 4 4 3 0 Nitrous oxide reductase propeller repeat PI3K_P85_iSH2 PF16454.5 EGG11886.1 - 0.042 13.5 1.9 0.064 12.9 1.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4407 PF14362.6 EGG11886.1 - 0.08 12.3 0.8 0.12 11.7 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4402 PF14352.6 EGG11886.1 - 0.1 13.3 0.0 1.7 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4402) Leu_zip PF15294.6 EGG11886.1 - 0.1 12.1 2.7 0.16 11.5 2.7 1.1 1 0 0 1 1 1 0 Leucine zipper Phage_GP20 PF06810.11 EGG11886.1 - 0.13 12.1 3.3 0.22 11.3 3.3 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 TMPIT PF07851.13 EGG11886.1 - 0.18 11.0 4.6 0.25 10.6 4.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3037 PF11236.8 EGG11886.1 - 0.19 12.2 0.5 0.37 11.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Atg14 PF10186.9 EGG11886.1 - 0.19 10.8 3.5 0.3 10.1 3.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 IFT57 PF10498.9 EGG11886.1 - 0.26 10.2 3.6 0.37 9.7 3.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Sec2p PF06428.11 EGG11886.1 - 0.31 11.0 4.0 0.59 10.1 4.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p PspA_IM30 PF04012.12 EGG11886.1 - 0.31 10.6 3.5 0.45 10.1 3.5 1.1 1 0 0 1 1 1 0 PspA/IM30 family Rootletin PF15035.6 EGG11886.1 - 0.34 10.9 5.6 0.52 10.3 5.6 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3584 PF12128.8 EGG11886.1 - 0.38 8.2 4.2 0.54 7.7 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 EGG11886.1 - 0.4 10.1 8.4 0.59 9.5 8.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 UPF0242 PF06785.11 EGG11886.1 - 0.49 10.5 6.1 0.77 9.8 6.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prp19 PF08606.11 EGG11886.1 - 0.5 10.4 2.2 1 9.4 1.4 1.9 1 1 1 2 2 2 0 Prp19/Pso4-like Tmemb_cc2 PF10267.9 EGG11886.1 - 0.5 9.4 3.3 0.76 8.9 3.3 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MAD PF05557.13 EGG11886.1 - 0.54 8.6 5.6 0.75 8.1 5.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Proteasome_A_N PF10584.9 EGG11886.1 - 0.66 9.7 7.3 80 3.1 0.0 5.1 5 0 0 5 5 4 0 Proteasome subunit A N-terminal signature CENP-F_leu_zip PF10473.9 EGG11886.1 - 0.75 9.8 7.5 1.3 9.0 7.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 EGG11886.1 - 0.75 10.0 7.8 1.3 9.2 7.8 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc24 PF08286.11 EGG11886.1 - 0.99 9.7 3.8 1.9 8.8 3.5 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 EzrA PF06160.12 EGG11886.1 - 1.2 7.2 4.1 1.7 6.7 4.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3450 PF11932.8 EGG11886.1 - 6.8 5.9 6.7 10 5.3 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YlqD PF11068.8 EGG11886.1 - 7.3 7.0 6.1 13 6.2 6.1 1.3 1 0 0 1 1 1 0 YlqD protein PIP5K PF01504.18 EGG11887.1 - 3e-100 335.0 0.0 4.1e-100 334.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Omega_Repress PF07764.11 EGG11890.1 - 0.11 13.0 0.0 2.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Omega Transcriptional Repressor FadA PF09403.10 EGG11892.1 - 0.1 13.1 3.7 0.12 12.9 2.0 1.9 2 0 0 2 2 2 0 Adhesion protein FadA DNA_pol_B_thumb PF14791.6 EGG11893.1 - 0.047 13.9 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta thumb GCM PF03615.15 EGG11894.1 - 0.0025 17.7 2.1 0.0068 16.3 0.4 2.3 2 0 0 2 2 2 1 GCM motif protein RXLR PF16810.5 EGG11894.1 - 0.031 14.7 0.2 0.12 12.8 0.2 2.0 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Macoilin PF09726.9 EGG11894.1 - 0.16 10.5 9.6 0.22 10.1 9.6 1.1 1 0 0 1 1 1 0 Macoilin family MRP PF09387.10 EGG11899.1 - 0.015 15.3 0.2 0.025 14.6 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP Sad1_UNC PF07738.13 EGG11900.1 - 4.1e-27 94.8 0.0 5.1e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SlyX PF04102.12 EGG11902.1 - 0.053 14.1 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 SlyX HTH_56 PF18662.1 EGG11905.1 - 0.15 12.1 0.0 33 4.6 0.0 2.8 3 0 0 3 3 3 0 Cch helix turn helix domain XPG_N PF00752.17 EGG11906.1 - 3.7e-25 88.3 0.0 6.4e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGG11906.1 - 1.3e-19 70.4 0.0 2.4e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EGG11906.1 - 4e-05 23.2 0.0 6.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.17 EGG11906.1 - 0.0019 18.2 0.0 0.0052 16.8 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG11906.1 - 0.0066 16.6 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat 5_3_exonuc PF01367.20 EGG11906.1 - 0.0078 16.8 0.0 0.016 15.8 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 EGG11906.1 - 0.13 12.9 0.3 6.8 7.4 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain TPR_1 PF00515.28 EGG11906.1 - 0.17 11.8 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Ntox37 PF15535.6 EGG11908.1 - 0.082 13.3 7.5 16 6.0 0.1 3.3 1 1 2 3 3 3 0 Bacterial toxin 37 Endomucin PF07010.12 EGG11908.1 - 1.1 9.2 14.7 1.4 8.8 14.7 1.1 1 0 0 1 1 1 0 Endomucin DUF3736 PF12540.8 EGG11908.1 - 2.5 8.2 24.3 1.8e+04 -12.7 24.0 4.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3736) zf-RING_2 PF13639.6 EGG11909.1 - 0.0096 16.2 3.1 0.0096 16.2 3.1 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EGG11909.1 - 0.023 14.4 5.8 0.058 13.1 5.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger LSM PF01423.22 EGG11910.1 - 1e-16 60.3 0.4 1.3e-16 60.0 0.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGG11910.1 - 0.018 15.2 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 EGG11910.1 - 0.055 13.1 0.1 0.085 12.5 0.1 1.3 1 0 0 1 1 1 0 Hfq protein ATP-synt_E PF05680.12 EGG11911.1 - 0.33 11.3 4.3 0.25 11.7 0.9 2.1 2 0 0 2 2 2 0 ATP synthase E chain PBP_sp32 PF07222.12 EGG11911.1 - 6 6.2 7.9 11 5.4 7.9 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ntox37 PF15535.6 EGG11913.1 - 0.079 13.4 5.3 10 6.6 0.2 3.2 1 1 2 3 3 3 0 Bacterial toxin 37 Cornifin PF02389.15 EGG11913.1 - 0.19 11.9 12.2 1.1 9.4 10.8 2.1 1 1 1 2 2 2 0 Cornifin (SPRR) family DUF1582 PF07621.11 EGG11913.1 - 0.29 11.1 22.0 3.5 7.7 1.7 5.3 4 2 1 5 5 5 0 Protein of unknown function (DUF1582) MIP PF00230.20 EGG11914.1 - 4.2e-30 105.1 3.7 3e-21 76.2 0.7 2.1 2 0 0 2 2 2 2 Major intrinsic protein CN_hydrolase PF00795.22 EGG11915.1 - 5.3e-17 62.0 0.0 1.5e-13 50.7 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase Parathyroid PF01279.17 EGG11916.1 - 0.0036 17.9 10.2 3 8.5 8.3 3.8 2 1 0 2 2 2 1 Parathyroid hormone family Glyco_transf_52 PF07922.11 EGG11916.1 - 0.017 14.4 0.6 0.24 10.6 0.2 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 52 DPM3 PF08285.11 EGG11916.1 - 0.11 12.7 0.9 5.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) O-antigen_lig PF13425.6 EGG11916.1 - 0.17 10.7 1.5 0.25 10.1 1.5 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3775 PF12616.8 EGG11916.1 - 0.19 11.8 4.1 1.4 9.0 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3775) FAA_hydro_N_2 PF18288.1 EGG11916.1 - 0.31 11.5 3.5 0.53 10.7 0.2 2.6 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 DGF-1_C PF11040.8 EGG11916.1 - 4.1 7.5 8.7 2.1 8.4 2.7 2.8 2 1 1 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Aldedh PF00171.22 EGG11917.1 - 1.9e-174 580.6 0.0 2.1e-174 580.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGG11917.1 - 0.0005 19.6 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 EGG11917.1 - 0.023 13.8 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) HRDC PF00570.23 EGG11917.1 - 0.17 11.9 0.0 2.9 8.0 0.0 2.4 2 0 0 2 2 2 0 HRDC domain DUF667 PF05018.13 EGG11918.1 - 2.6e-25 89.2 1.7 1.4e-24 86.8 1.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF667) Baculo_PEP_C PF04513.12 EGG11919.1 - 0.048 13.7 2.3 0.13 12.3 0.4 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SIR4_SID PF16991.5 EGG11920.1 - 1.7 8.7 4.5 13 5.8 0.0 3.0 3 0 0 3 3 3 0 Sir4 SID domain BLM10_mid PF16507.5 EGG11922.1 - 2.4e-155 518.2 2.8 3e-155 517.8 0.1 2.5 3 0 0 3 3 3 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EGG11922.1 - 1.6e-26 92.0 0.0 8.3e-26 89.7 0.0 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.22 EGG11922.1 - 8.3e-06 25.6 6.1 0.00091 19.3 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 EGG11922.1 - 2.1e-05 24.8 0.6 0.0048 17.3 0.1 4.5 6 1 1 7 7 7 2 HEAT repeats HEAT_EZ PF13513.6 EGG11922.1 - 0.0023 18.4 0.5 0.015 15.8 0.1 2.7 2 0 0 2 2 2 1 HEAT-like repeat Cnd1 PF12717.7 EGG11922.1 - 0.009 16.1 0.0 0.066 13.2 0.1 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 BLM10_N PF16547.5 EGG11922.1 - 0.024 14.9 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Sec1 PF00995.23 EGG11923.1 - 5.6e-110 369.3 0.0 6.4e-110 369.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Vma12 PF11712.8 EGG11924.1 - 1.9e-14 53.9 0.0 2.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase MFS_1 PF07690.16 EGG11925.1 - 5.2e-28 98.0 21.3 5.2e-28 98.0 21.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_U4 PF03419.13 EGG11925.1 - 9.7 5.4 18.6 0.4 9.9 5.2 2.9 2 1 0 2 2 2 0 Sporulation factor SpoIIGA MFS_1 PF07690.16 EGG11926.1 - 1.7e-35 122.6 31.5 1.7e-35 122.6 31.5 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EGG11927.1 - 6.8e-35 120.6 25.9 6.8e-35 120.6 25.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily P5-ATPase PF12409.8 EGG11927.1 - 0.36 10.9 1.9 0.44 10.7 0.3 2.0 2 0 0 2 2 2 0 P5-type ATPase cation transporter Coatomer_WDAD PF04053.14 EGG11928.1 - 4.5e-144 480.8 0.0 9e-144 479.8 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 EGG11928.1 - 7.1e-123 410.3 0.0 9.1e-123 410.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EGG11928.1 - 3.1e-44 148.1 12.8 2e-09 37.9 0.5 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG11928.1 - 6.2e-12 45.6 0.1 0.00097 19.4 0.0 5.7 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG11928.1 - 0.016 13.9 5.4 1.6 7.3 0.0 4.2 3 1 2 5 5 5 0 Nucleoporin Nup120/160 Clathrin PF00637.20 EGG11928.1 - 0.056 13.3 0.2 0.58 10.0 0.0 2.5 3 0 0 3 3 3 0 Region in Clathrin and VPS WD40_like PF17005.5 EGG11928.1 - 0.068 12.5 0.0 0.53 9.6 0.0 2.4 2 1 1 3 3 3 0 WD40-like domain Nucleoporin_N PF08801.11 EGG11928.1 - 0.12 11.1 1.7 7.5 5.2 0.0 3.5 2 1 2 4 4 4 0 Nup133 N terminal like Ribosomal_L35p PF01632.19 EGG11929.1 - 9.2e-08 32.5 3.6 2e-07 31.4 3.6 1.6 1 1 0 1 1 1 1 Ribosomal protein L35 Cmc1 PF08583.10 EGG11930.1 - 3.4e-11 43.0 0.1 4e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like MAAL_C PF07476.11 EGG11930.1 - 0.051 12.7 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus 3HCDH_N PF02737.18 EGG11932.1 - 0.048 13.5 0.4 0.097 12.5 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Melibiase_2 PF16499.5 EGG11933.1 - 2.3e-23 82.8 0.3 5.2e-12 45.5 0.0 2.8 2 1 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 EGG11933.1 - 3.2e-05 23.9 0.2 6.1e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EGG11933.1 - 0.00024 20.2 0.0 0.0045 16.0 0.0 2.1 2 0 0 2 2 2 1 Melibiase MFS_1 PF07690.16 EGG11934.1 - 3.1e-34 118.5 23.6 3.1e-34 118.5 23.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG11934.1 - 0.00012 21.1 14.4 0.00027 19.9 14.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EGG11934.1 - 0.00019 20.0 0.6 0.0003 19.4 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TOM13 PF08219.11 EGG11934.1 - 0.01 15.8 0.1 0.33 10.9 0.0 2.4 2 0 0 2 2 2 0 Outer membrane protein TOM13 DUF5495 PF17599.2 EGG11934.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5495) Orthopox_A5L PF06193.11 EGG11935.1 - 0.032 13.7 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Usp PF00582.26 EGG11937.1 - 5.8e-10 39.8 0.1 1.5e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 Universal stress protein family FF PF01846.19 EGG11939.1 - 9.5e-25 86.5 2.1 2.3e-11 43.7 0.0 4.9 4 0 0 4 4 4 2 FF domain WW PF00397.26 EGG11939.1 - 8.1e-14 51.4 21.1 6e-07 29.5 3.0 3.1 3 0 0 3 3 3 2 WW domain Helicase_IV_N PF12462.8 EGG11939.1 - 0.03 14.3 0.1 0.096 12.6 0.1 1.8 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Glyco_hyd_101C PF17451.2 EGG11939.1 - 1.4 9.2 7.7 1.3 9.4 0.3 2.8 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain CKS PF01111.19 EGG11940.1 - 3e-33 113.9 0.6 3.9e-33 113.5 0.6 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF3844 PF12955.7 EGG11941.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) HMG_CoA_synt_N PF01154.17 EGG11943.1 - 2.5e-87 291.2 0.2 6.1e-87 290.0 0.1 1.7 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EGG11943.1 - 2.8e-83 279.8 0.8 3.4e-83 279.5 0.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal RNA_pol_Rpb1_R PF05001.13 EGG11943.1 - 1.4 9.4 8.3 8.3 7.0 2.2 2.7 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat Carb_kinase PF01256.17 EGG11947.1 - 0.043 13.3 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate kinase PX PF00787.24 EGG11947.1 - 0.12 12.4 0.8 0.22 11.5 0.3 1.6 1 1 0 2 2 2 0 PX domain DUF3253 PF11625.8 EGG11948.1 - 0.055 13.7 0.1 18 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) ERCC4 PF02732.15 EGG11949.1 - 1.8e-19 70.5 0.5 3.9e-19 69.4 0.5 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 EGG11949.1 - 5.2e-05 23.5 0.2 0.00014 22.1 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Rad9 PF04139.13 EGG11950.1 - 5.8e-34 117.7 2.8 9.7e-34 116.9 2.8 1.4 1 0 0 1 1 1 1 Rad9 Flavodoxin_2 PF02525.17 EGG11950.1 - 0.038 13.7 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin-like fold CxC5 PF18718.1 EGG11951.1 - 5e-25 87.8 5.5 7.6e-25 87.3 5.5 1.2 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG11952.1 - 1.9e-11 44.1 4.0 6.1e-11 42.4 4.0 1.9 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases DUF913 PF06025.12 EGG11954.1 - 0.076 12.0 0.2 0.12 11.3 0.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FKS1_dom1 PF14288.6 EGG11955.1 - 8.5e-17 61.7 0.6 3.5e-10 40.3 0.0 2.3 1 1 1 2 2 2 2 1,3-beta-glucan synthase subunit FKS1, domain-1 zf-HC5HC2H_2 PF13832.6 EGG11957.1 - 8.6e-32 109.6 11.8 3.3e-31 107.7 6.3 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGG11957.1 - 5.6e-24 84.2 15.0 1.4e-23 83.0 3.9 3.0 3 0 0 3 3 3 2 PHD-like zinc-binding domain EPL1 PF10513.9 EGG11957.1 - 2.7e-19 70.1 0.1 3.6e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.6 EGG11957.1 - 1.4e-15 56.6 2.6 1.4e-15 56.6 2.6 3.8 5 0 0 5 5 5 1 PHD-finger PHD PF00628.29 EGG11957.1 - 1.1e-12 47.6 25.1 2e-12 46.8 5.4 3.4 4 0 0 4 4 4 2 PHD-finger C1_1 PF00130.22 EGG11957.1 - 0.0021 17.9 0.2 0.0021 17.9 0.2 3.4 3 1 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 EGG11957.1 - 0.0032 17.1 4.2 0.0032 17.1 4.2 2.6 2 1 1 3 3 3 1 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.16 EGG11957.1 - 0.012 15.8 1.2 0.012 15.8 1.2 2.6 2 1 1 3 3 3 0 FYVE-type zinc finger Prok-RING_1 PF14446.6 EGG11957.1 - 0.02 14.8 3.3 0.02 14.8 3.3 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 EGG11957.1 - 0.059 13.7 8.7 0.059 13.7 8.7 3.2 3 1 0 3 3 3 0 RING-like domain C1_2 PF03107.16 EGG11957.1 - 5.2 7.5 26.4 0.11 12.9 1.5 3.5 4 1 0 4 4 4 0 C1 domain Bromodomain PF00439.25 EGG11958.1 - 1.2e-19 70.2 0.3 1.4e-19 69.9 0.3 1.1 1 0 0 1 1 1 1 Bromodomain GvpG PF05120.12 EGG11959.1 - 2 8.5 12.7 7.7 6.6 4.0 2.5 2 0 0 2 2 2 0 Gas vesicle protein G DUF4281 PF14108.6 EGG11960.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) ubiquitin PF00240.23 EGG11961.1 - 6.5e-14 51.4 0.0 1.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Blt1 PF12754.7 EGG11961.1 - 3.2e-05 24.3 1.6 3.2e-05 24.3 1.6 1.6 1 1 0 1 1 1 1 Blt1 N-terminal domain Rad60-SLD PF11976.8 EGG11961.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EGG11961.1 - 0.001 19.1 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Blt1_C PF17183.4 EGG11961.1 - 0.021 14.4 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 Get5 carboxyl domain CRF1 PF10380.9 EGG11962.1 - 0.028 14.8 1.3 0.031 14.6 1.3 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 PITH PF06201.13 EGG11963.1 - 1.4e-21 77.3 0.0 1.8e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 PITH domain 5_nucleotid_C PF02872.18 EGG11964.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain B12-binding PF02310.19 EGG11964.1 - 0.084 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain EamA PF00892.20 EGG11965.1 - 4.2e-11 43.2 25.7 2.5e-06 27.7 2.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 EGG11965.1 - 5.4e-07 29.4 3.7 5.4e-07 29.4 3.7 1.6 1 1 1 2 2 2 1 Solute carrier family 35 DUF2340 PF10209.9 EGG11966.1 - 7e-45 152.4 1.1 8e-45 152.2 1.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) AhpC-TSA_2 PF13911.6 EGG11969.1 - 1.8e-09 37.7 0.0 6.7e-09 35.9 0.0 2.0 2 1 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGG11969.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family BING4CT PF08149.11 EGG11970.1 - 4.1e-37 125.8 2.3 1e-34 118.1 0.0 3.5 4 0 0 4 4 4 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EGG11970.1 - 2.1e-06 27.9 0.2 0.41 11.0 0.0 4.7 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG11970.1 - 3.8e-05 24.4 3.5 0.0027 18.5 0.0 4.2 3 1 0 3 3 3 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EGG11970.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.5 2 0 0 2 2 2 0 Coatomer WD associated region Mog1 PF04603.12 EGG11971.1 - 2e-37 128.6 0.0 2.5e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein GHL13 PF14883.6 EGG11971.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 Ribosomal_S19 PF00203.21 EGG11972.1 - 3.7e-34 116.5 0.3 5.3e-34 116.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 EGG11972.1 - 0.00011 22.3 0.0 0.00014 21.9 0.0 1.1 1 0 0 1 1 1 1 Flagellar assembly protein FliH SipA_VBS PF17985.1 EGG11973.1 - 0.0043 16.8 0.1 0.011 15.5 0.1 1.7 1 0 0 1 1 1 1 SipA vinculin binding site DUF2321 PF10083.9 EGG11973.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) CENP-T_C PF15511.6 EGG11974.1 - 0.075 13.2 0.2 1.4 9.1 0.1 2.2 1 1 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold Effector_1 PF04518.12 EGG11974.1 - 0.11 11.6 0.8 0.16 11.0 0.6 1.4 1 1 0 1 1 1 0 Effector from type III secretion system PTS_2-RNA PF01885.16 EGG11975.1 - 5.4e-64 215.6 0.0 6.3e-64 215.3 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family TFIID-31kDa PF02291.15 EGG11976.1 - 1.9e-42 144.2 0.0 2.4e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGG11976.1 - 1.9e-06 27.8 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_30kDa PF03540.13 EGG11976.1 - 0.002 18.1 0.2 0.0039 17.1 0.2 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Histone PF00125.24 EGG11976.1 - 0.026 14.9 0.0 0.047 14.0 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGG11976.1 - 0.041 14.3 0.1 0.072 13.5 0.1 1.4 1 0 0 1 1 1 0 CENP-S protein CENP-T_C PF15511.6 EGG11976.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EGG11977.1 - 6.2e-18 65.4 0.0 8.1e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGG11977.1 - 1e-17 63.6 0.7 2e-17 62.6 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGG11977.1 - 1e-05 25.7 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGG11979.1 - 3.8e-24 85.5 0.6 4.5e-24 85.3 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGG11979.1 - 1.4e-05 25.3 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGG11979.1 - 0.0039 17.6 0.0 0.0058 17.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A BEX PF04538.12 EGG11979.1 - 0.087 13.4 2.2 0.13 12.9 2.2 1.3 1 0 0 1 1 1 0 Brain expressed X-linked like family CENP-W PF15510.6 EGG11979.1 - 0.097 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 CENP-W protein Con-6 PF10346.9 EGG11980.1 - 1.1e-28 99.0 1.8 2.2e-13 50.0 0.3 2.1 2 0 0 2 2 2 2 Conidiation protein 6 DUF1539 PF07560.11 EGG11980.1 - 0.0018 18.4 0.7 1 9.5 0.1 2.1 1 1 1 2 2 2 2 Domain of Unknown Function (DUF1539) Ntox28 PF15605.6 EGG11980.1 - 0.0038 17.5 0.6 0.14 12.4 0.1 2.1 1 1 1 2 2 2 2 Bacterial toxin 28 Sterol_MT_C PF08498.10 EGG11981.1 - 7.9e-23 80.5 0.5 1.4e-22 79.8 0.5 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 EGG11981.1 - 1.6e-14 54.0 0.1 2.5e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG11981.1 - 9e-12 45.5 0.0 1.6e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG11981.1 - 8.9e-11 42.4 0.0 1.7e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGG11981.1 - 5.1e-09 35.8 0.1 6.5e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGG11981.1 - 5e-07 29.7 0.0 8.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG11981.1 - 1.1e-06 29.3 0.2 3.4e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 EGG11981.1 - 0.0014 18.2 0.2 0.0024 17.5 0.2 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 EGG11981.1 - 0.0015 17.8 0.1 0.0021 17.3 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.18 EGG11981.1 - 0.0053 16.1 0.0 0.0091 15.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGG11981.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RPN7 PF10602.9 EGG11983.1 - 8.4e-47 159.1 1.8 8.4e-47 159.1 1.8 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EGG11983.1 - 9.4e-15 55.0 1.7 1.1e-14 54.8 0.3 1.9 2 0 0 2 2 2 1 PCI domain Clr2_transil PF16761.5 EGG11984.1 - 8e-12 45.8 8.8 9.6e-12 45.6 6.6 2.4 2 0 0 2 2 2 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 EGG11984.1 - 1.3e-06 29.3 0.1 1.3e-06 29.3 0.1 2.2 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 Ntox44 PF15607.6 EGG11984.1 - 0.0082 16.4 1.3 0.023 15.0 0.8 2.0 2 0 0 2 2 2 1 Bacterial toxin 44 DNA_primase_S PF01896.19 EGG11985.1 - 1.3e-55 188.2 0.1 1.9e-55 187.6 0.1 1.3 1 0 0 1 1 1 1 DNA primase small subunit GNAT_acetyltran PF12746.7 EGG11985.1 - 7.7 6.0 6.2 4.8 6.7 0.3 2.6 2 1 1 3 3 3 0 GNAT acetyltransferase Sec23_trunk PF04811.15 EGG11987.1 - 6.4e-75 251.8 0.0 1e-74 251.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGG11987.1 - 2.9e-29 101.6 0.1 5.1e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EGG11987.1 - 9e-26 89.7 0.4 1.9e-25 88.7 0.1 1.7 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EGG11987.1 - 6.2e-16 58.2 7.0 1.2e-15 57.3 7.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGG11987.1 - 1.8e-15 56.6 0.0 6.3e-15 54.8 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat HAGH_C PF16123.5 EGG11988.1 - 5.4e-24 84.5 0.8 1.1e-23 83.6 0.8 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EGG11988.1 - 4.9e-08 33.2 0.3 4.5e-07 30.1 0.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGG11988.1 - 0.0096 15.5 0.3 0.13 11.8 0.2 2.7 1 1 1 3 3 3 1 Beta-lactamase superfamily domain CoA_transf_3 PF02515.17 EGG11990.1 - 1.9e-117 392.5 0.0 2.3e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DUF3613 PF12266.8 EGG11991.1 - 0.0011 18.7 2.0 0.003 17.3 2.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3613) F-box-like PF12937.7 EGG11992.1 - 0.079 12.9 0.1 0.2 11.6 0.1 1.8 1 1 0 1 1 1 0 F-box-like MCLC PF05934.11 EGG11992.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) RPAP2_Rtr1 PF04181.13 EGG11994.1 - 0.08 13.3 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Rtr1/RPAP2 family RPAP2_Rtr1 PF04181.13 EGG11995.1 - 0.08 13.3 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Rtr1/RPAP2 family ParA PF10609.9 EGG11996.1 - 2.8e-89 298.8 0.0 3.4e-89 298.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGG11996.1 - 3.7e-14 52.9 0.0 7.3e-14 51.9 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EGG11996.1 - 1.1e-06 28.1 1.3 2.8e-05 23.5 0.6 2.2 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 EGG11996.1 - 2.9e-05 24.1 0.2 0.00019 21.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 EGG11996.1 - 0.00022 20.6 0.0 0.004 16.5 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ CBP_BcsQ PF06564.12 EGG11996.1 - 0.0036 16.8 0.2 0.012 15.1 0.2 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 EGG11996.1 - 0.029 14.3 0.2 0.075 12.9 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 EGG11996.1 - 0.041 13.5 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.6 EGG11996.1 - 0.045 13.6 0.1 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain SelB-wing_3 PF09107.11 EGG11996.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Elongation factor SelB, winged helix NB-ARC PF00931.22 EGG11996.1 - 0.15 11.2 0.1 0.24 10.5 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Fer4_NifH PF00142.18 EGG11996.1 - 0.15 11.4 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PcrB PF01884.17 EGG11996.1 - 0.21 11.0 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 PcrB family MeaB PF03308.16 EGG11996.1 - 0.22 10.4 0.1 0.34 9.9 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SNF2_N PF00176.23 EGG11998.1 - 1.1e-56 192.1 0.1 1.4e-55 188.5 0.0 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG11998.1 - 2.5e-16 60.0 0.0 1.1e-15 58.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG11998.1 - 2.1e-07 31.1 0.0 5.9e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGG11998.1 - 0.00026 20.7 0.0 0.00082 19.1 0.0 1.8 1 1 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 EGG11998.1 - 0.006 15.8 0.1 0.014 14.6 0.1 1.6 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EGG11998.1 - 0.012 15.4 0.0 0.41 10.4 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase GIDA PF01134.22 EGG12000.1 - 8.7e-09 34.9 0.3 1.7e-07 30.7 0.4 2.0 1 1 1 2 2 2 2 Glucose inhibited division protein A DASH_Spc19 PF08287.11 EGG12002.1 - 7.6e-24 84.4 16.3 8.8e-24 84.2 16.3 1.1 1 0 0 1 1 1 1 Spc19 FlgN PF05130.12 EGG12002.1 - 0.74 10.3 16.2 0.55 10.7 4.2 2.2 1 1 1 2 2 2 0 FlgN protein DUF948 PF06103.11 EGG12002.1 - 2.1 8.7 5.6 12 6.2 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AvrM-A PF18241.1 EGG12004.1 - 4.4e-56 189.4 10.2 4.4e-56 189.4 10.2 2.4 2 1 0 2 2 2 1 Flax-rust effector AvrM-A AvrM_N PF18247.1 EGG12004.1 - 5e-31 106.5 0.6 5e-31 106.5 0.6 2.8 2 1 0 2 2 2 1 Flax-rust effector AvrM N-terminal domain DUF1421 PF07223.11 EGG12004.1 - 0.17 11.7 0.1 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 UBA-like domain (DUF1421) PNP_UDP_1 PF01048.20 EGG12005.1 - 1.4e-39 135.7 0.0 2e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Apolipoprotein PF01442.18 EGG12007.1 - 7.5e-05 22.7 4.1 7.5e-05 22.7 4.1 1.8 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Perilipin PF03036.16 EGG12007.1 - 0.00011 21.3 11.2 0.00023 20.3 0.2 2.5 1 1 1 2 2 2 1 Perilipin family OmpH PF03938.14 EGG12007.1 - 0.0059 17.0 6.3 0.0059 17.0 6.3 2.6 2 2 0 2 2 2 1 Outer membrane protein (OmpH-like) Chorion_S16 PF05836.12 EGG12007.1 - 0.04 14.2 1.6 0.075 13.3 0.7 1.8 1 1 1 2 2 2 0 Chorion protein S16 DUF1451 PF07295.11 EGG12007.1 - 0.076 13.0 1.3 0.14 12.2 1.0 1.6 1 1 0 1 1 1 0 Zinc-ribbon containing domain P22_AR_C PF10548.9 EGG12007.1 - 0.081 13.1 0.2 1.2 9.4 0.0 2.8 2 1 1 3 3 3 0 P22AR C-terminal domain GlutR_dimer PF00745.20 EGG12007.1 - 0.14 12.6 1.0 6.8 7.2 0.1 2.9 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain REF PF05755.12 EGG12007.1 - 0.2 11.4 10.0 2.7 7.8 0.2 3.2 1 1 2 3 3 3 0 Rubber elongation factor protein (REF) Baculo_PEP_C PF04513.12 EGG12007.1 - 0.21 11.6 3.8 0.68 10.0 1.8 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EGG12007.1 - 0.24 11.5 3.7 4.3 7.4 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EGG12007.1 - 0.26 10.1 7.4 0.4 9.5 7.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 EGG12007.1 - 0.39 11.0 2.0 16 5.8 1.0 3.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ApoLp-III PF07464.11 EGG12007.1 - 0.46 10.6 16.4 0.64 10.1 9.0 3.2 2 1 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 EGG12007.1 - 0.59 8.0 6.2 0.85 7.5 5.6 1.6 1 1 1 2 2 2 0 Prominin WXG100 PF06013.12 EGG12007.1 - 0.74 10.1 5.8 1.6 9.0 0.2 3.3 3 2 0 3 3 3 0 Proteins of 100 residues with WXG DUF2408 PF10303.9 EGG12007.1 - 0.88 10.1 6.4 0.89 10.1 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) YkyA PF10368.9 EGG12007.1 - 4.1 7.0 9.9 1.9 8.1 5.9 2.0 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Sybindin PF04099.12 EGG12009.1 - 1.1e-38 132.3 0.0 1.2e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EGG12009.1 - 1.4e-07 31.7 0.0 1.9e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Ctr PF04145.15 EGG12010.1 - 1.5e-28 100.2 3.0 1.9e-28 100.0 3.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Peptidase_S30 PF01577.16 EGG12011.1 - 9.2 5.8 15.7 0.56 9.8 7.0 2.3 2 0 0 2 2 2 0 Potyvirus P1 protease Rcd1 PF04078.13 EGG12012.1 - 1.3e-122 408.1 3.2 1.5e-122 407.9 3.2 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pigment_DH PF06324.11 EGG12012.1 - 0.1 12.7 0.3 0.33 11.1 0.3 1.9 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) adh_short PF00106.25 EGG12014.1 - 8.8e-37 126.5 0.3 1.1e-36 126.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG12014.1 - 5.4e-31 107.9 0.1 9e-31 107.2 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG12014.1 - 3.8e-10 40.0 2.0 6.2e-09 36.0 1.9 2.3 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EGG12014.1 - 7.3e-06 25.2 1.1 2.3e-05 23.5 1.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGG12014.1 - 0.0007 19.1 0.1 0.0028 17.1 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGG12014.1 - 0.015 15.2 0.1 0.021 14.7 0.1 1.3 1 1 0 1 1 1 0 NAD(P)H-binding CxC5 PF18718.1 EGG12016.1 - 1e-06 28.8 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Alpha_kinase PF02816.18 EGG12017.1 - 2.9e-07 30.8 1.9 6.6e-07 29.6 1.9 1.6 1 1 0 1 1 1 1 Alpha-kinase family Apolipoprotein PF01442.18 EGG12019.1 - 0.004 17.0 1.1 0.0049 16.8 0.1 1.6 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Med29 PF11568.8 EGG12019.1 - 0.011 16.0 0.2 0.025 14.8 0.2 1.7 1 1 0 1 1 1 0 Mediator complex subunit 29 DUF1640 PF07798.11 EGG12019.1 - 0.025 14.6 0.1 0.056 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1493 PF07377.12 EGG12019.1 - 0.066 13.7 1.0 2 8.9 0.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1493) Baculo_PEP_C PF04513.12 EGG12019.1 - 0.17 11.9 9.0 0.56 10.2 9.0 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAM76 PF16046.5 EGG12019.1 - 0.19 11.1 1.5 0.27 10.5 1.5 1.1 1 0 0 1 1 1 0 FAM76 protein VPS9 PF02204.18 EGG12020.1 - 1.3e-30 105.7 0.0 2.8e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EGG12020.1 - 2.9e-07 30.7 0.3 2e-06 28.0 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF5601) CUE PF02845.16 EGG12020.1 - 4.7e-05 23.0 0.2 0.00037 20.1 0.1 2.3 2 0 0 2 2 2 1 CUE domain DMA PF03474.14 EGG12020.1 - 0.0098 15.5 0.4 0.026 14.1 0.1 1.9 2 0 0 2 2 2 1 DMRTA motif Peptidase_M16_C PF05193.21 EGG12020.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase M16 inactive domain Kri1 PF05178.12 EGG12020.1 - 0.15 12.6 3.2 0.48 11.0 3.2 1.8 1 0 0 1 1 1 0 KRI1-like family HORMA PF02301.18 EGG12021.1 - 7.4e-62 208.7 3.3 1.3e-61 207.9 0.0 2.5 2 0 0 2 2 2 1 HORMA domain PHD PF00628.29 EGG12021.1 - 1.7e-05 24.6 9.3 3.2e-05 23.7 9.3 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGG12021.1 - 0.005 16.4 2.5 0.0098 15.4 2.5 1.5 1 0 0 1 1 1 1 PHD-finger MarR PF01047.22 EGG12021.1 - 0.16 11.9 0.0 0.16 11.9 0.0 3.2 3 0 0 3 3 3 0 MarR family RasGEF_N PF00618.20 EGG12021.1 - 6.1 7.1 7.3 0.3 11.3 0.4 2.4 3 0 0 3 3 3 0 RasGEF N-terminal motif GPI-anchored PF10342.9 EGG12022.1 - 7.5e-05 23.4 0.1 0.00019 22.1 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family COE1_HLH PF16423.5 EGG12022.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain Pkinase PF00069.25 EGG12024.1 - 1.7e-75 253.8 0.0 2e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG12024.1 - 1.6e-32 112.8 0.0 5.3e-32 111.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG12024.1 - 0.0069 15.7 0.0 0.017 14.4 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGG12024.1 - 0.037 13.0 0.1 0.14 11.1 0.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EGG12024.1 - 0.039 13.5 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGG12024.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGG12024.1 - 0.18 10.8 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 HMG_box PF00505.19 EGG12025.1 - 0.037 14.4 0.1 0.096 13.1 0.1 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box Pkinase PF00069.25 EGG12026.1 - 9.8e-07 28.4 0.0 9.8e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG12026.1 - 0.0013 18.1 0.0 0.0013 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3953 PF13129.6 EGG12027.1 - 3.6 7.4 7.1 12 5.7 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) MBOAT PF03062.19 EGG12029.1 - 6.4e-45 154.0 21.9 6.4e-45 154.0 21.9 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Na_K-ATPase PF00287.18 EGG12029.1 - 0.12 11.5 0.1 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain Ribosomal_L28e PF01778.17 EGG12030.1 - 1.4e-36 125.8 0.3 1.4e-36 125.8 0.3 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EGG12030.1 - 2.6e-26 92.2 16.3 4.1e-26 91.5 16.3 1.3 1 0 0 1 1 1 1 Mak16 protein C-terminal region PYC_OADA PF02436.18 EGG12030.1 - 0.11 12.3 0.8 0.16 11.7 0.8 1.3 1 0 0 1 1 1 0 Conserved carboxylase domain DUF1547 PF07577.11 EGG12033.1 - 0.04 14.3 0.0 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) HSP90 PF00183.18 EGG12035.1 - 5.9e-229 761.2 30.6 7.5e-229 760.9 30.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGG12035.1 - 6.6e-16 58.8 0.0 1.5e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGG12035.1 - 7.4e-12 45.3 0.1 2.5e-11 43.5 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1198 PF06711.11 EGG12035.1 - 0.097 12.7 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) Cofac_haem_bdg PF04187.13 EGG12035.1 - 0.13 12.2 0.6 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN DUF932 PF06067.11 EGG12036.1 - 0.52 10.0 9.2 0.076 12.8 2.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF932) TipAS PF07739.13 EGG12036.1 - 1.5 9.4 7.5 0.69 10.5 3.5 2.1 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain OmpH PF03938.14 EGG12036.1 - 2.2 8.6 11.9 0.47 10.8 4.4 2.2 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 EGG12036.1 - 4.9 6.6 12.9 13 5.2 12.9 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 EGG12036.1 - 4.9 6.3 12.7 0.71 9.1 4.2 2.1 1 1 1 2 2 2 0 TMPIT-like protein Vps62 PF06101.11 EGG12037.1 - 9.9e-09 34.0 0.8 6.6e-08 31.3 0.1 2.0 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 RRM_1 PF00076.22 EGG12041.1 - 7.5e-29 99.4 2.9 3.5e-14 52.4 0.0 5.2 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG12041.1 - 3.8e-05 23.5 0.0 0.15 12.0 0.0 3.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EGG12041.1 - 0.00021 21.4 0.0 0.0042 17.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RRM_9 PF18444.1 EGG12041.1 - 0.05 13.5 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif DUF3887 PF13026.6 EGG12041.1 - 0.12 13.2 1.3 1.1 10.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3887) CxC5 PF18718.1 EGG12042.1 - 1.5e-26 92.8 6.8 3.5e-26 91.6 6.8 1.7 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG12042.1 - 9.4e-21 73.9 0.5 9.4e-21 73.9 0.5 2.2 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases zf-UBP PF02148.19 EGG12042.1 - 0.28 11.5 2.8 1.5 9.2 2.0 2.5 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein FTHFS PF01268.19 EGG12049.1 - 0.0023 16.2 0.1 0.0023 16.2 0.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase NT-C2 PF10358.9 EGG12053.1 - 1.3e-16 60.6 0.1 7.2e-12 45.2 0.0 2.9 2 1 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Nup35_RRM PF05172.13 EGG12055.1 - 2.9e-15 56.1 0.0 5.7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EGG12055.1 - 3.2e-05 23.8 0.0 5.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TMEM154 PF15102.6 EGG12056.1 - 0.091 12.7 0.0 0.091 12.7 0.0 3.7 3 0 0 3 3 3 0 TMEM154 protein family MHYT PF03707.16 EGG12056.1 - 0.2 11.8 0.1 0.41 10.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat EphA2_TM PF14575.6 EGG12056.1 - 0.23 12.3 0.6 1.3 10.0 0.1 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ABC2_membrane_3 PF12698.7 EGG12056.1 - 0.31 10.1 3.7 0.39 9.8 0.5 2.5 3 0 0 3 3 3 0 ABC-2 family transporter protein Shisa PF13908.6 EGG12056.1 - 2.3 8.4 0.0 2.3 8.4 0.0 3.7 3 1 1 5 5 5 0 Wnt and FGF inhibitory regulator PepX_C PF08530.10 EGG12057.1 - 0.053 13.4 1.5 0.063 13.2 1.5 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Rhomboid PF01694.22 EGG12058.1 - 2.3e-20 73.1 10.8 8.7e-20 71.2 10.8 2.0 1 1 0 1 1 1 1 Rhomboid family zf-C2H2 PF00096.26 EGG12059.1 - 0.00087 19.6 7.2 0.55 10.8 3.2 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG12059.1 - 0.0085 16.9 7.5 0.45 11.5 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGG12059.1 - 0.012 15.4 3.0 0.64 9.8 0.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 EGG12059.1 - 0.031 14.6 1.1 0.098 13.0 1.1 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Elf1 PF05129.13 EGG12059.1 - 0.082 13.0 1.2 0.25 11.4 1.2 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.6 EGG12059.1 - 0.39 11.2 15.5 0.16 12.5 1.0 3.6 3 0 0 3 3 3 0 Zinc-finger double domain Sgf11 PF08209.11 EGG12059.1 - 1.4 8.5 8.0 0.27 10.8 2.2 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 EGG12059.1 - 1.7 8.7 10.0 5.4 7.0 0.7 3.3 3 1 0 3 3 3 0 zinc-finger of a C2HC-type Retrotran_gag_2 PF14223.6 EGG12060.1 - 0.0096 15.6 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF98 PF01947.16 EGG12060.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase HSP70 PF00012.20 EGG12061.1 - 8.6e-69 232.3 0.3 1.3e-68 231.7 0.3 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGG12061.1 - 2.7e-10 39.6 0.0 1.5e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein NTF2 PF02136.20 EGG12063.1 - 1.6e-29 102.9 0.1 2.8e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EGG12063.1 - 6.2e-09 35.6 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4518 PF15008.6 EGG12063.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Metallophos PF00149.28 EGG12065.1 - 3.2e-15 57.2 0.5 6.2e-15 56.2 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 4HBT PF03061.22 EGG12066.1 - 1.4e-22 79.8 2.3 8e-12 45.3 0.1 2.4 2 0 0 2 2 2 2 Thioesterase superfamily ATP-synt_ab PF00006.25 EGG12067.1 - 1.3e-72 243.9 0.0 1.9e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EGG12067.1 - 1.3e-41 141.9 0.0 2.3e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EGG12067.1 - 1.8e-18 66.8 1.8 4.7e-18 65.5 1.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF676 PF05057.14 EGG12068.1 - 0.0029 17.2 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGG12068.1 - 0.0053 16.6 0.0 0.024 14.5 0.0 1.8 1 1 1 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 EGG12068.1 - 0.024 15.2 0.0 0.031 14.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGG12068.1 - 0.066 12.7 0.1 10 5.5 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.13 EGG12068.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.15 EGG12068.1 - 0.17 11.0 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase ATP-synt_D PF01813.17 EGG12069.1 - 0.0022 17.8 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 2 ATP synthase subunit D Guanylate_kin PF00625.21 EGG12070.1 - 2.7e-53 180.3 0.0 3.4e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_22 PF13401.6 EGG12070.1 - 0.00012 22.4 0.0 0.00085 19.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGG12070.1 - 0.00019 21.9 0.0 0.00075 19.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EGG12070.1 - 0.0006 20.0 0.0 0.002 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGG12070.1 - 0.00088 19.2 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 EGG12070.1 - 0.0016 18.7 0.1 0.0062 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGG12070.1 - 0.0025 18.4 0.0 0.0034 17.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 EGG12070.1 - 0.0028 18.2 0.0 0.011 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGG12070.1 - 0.0081 16.2 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EGG12070.1 - 0.01 15.5 0.4 0.061 13.1 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EGG12070.1 - 0.012 15.1 0.2 0.019 14.5 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGG12070.1 - 0.021 14.5 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGG12070.1 - 0.035 14.0 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 EGG12070.1 - 0.044 13.8 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGG12070.1 - 0.045 14.1 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EGG12070.1 - 0.05 13.5 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EGG12070.1 - 0.055 13.2 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGG12070.1 - 0.071 13.5 0.1 0.17 12.3 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGG12070.1 - 0.088 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI VRR_NUC PF08774.11 EGG12070.1 - 0.093 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 VRR-NUC domain Roc PF08477.13 EGG12070.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Adeno_IVa2 PF02456.15 EGG12070.1 - 0.19 10.5 0.1 0.3 9.8 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Voltage_CLC PF00654.20 EGG12071.1 - 9.8e-85 284.9 29.1 9.8e-85 284.9 29.1 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGG12071.1 - 1.1e-05 25.8 0.0 0.042 14.3 0.0 2.9 3 0 0 3 3 3 2 CBS domain Glyco_tranf_2_3 PF13641.6 EGG12072.1 - 4.7e-30 105.2 0.1 9.2e-30 104.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGG12072.1 - 6.7e-11 42.3 0.0 1.3e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGG12072.1 - 4.6e-08 32.7 0.0 1.3e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 PIG-P PF08510.12 EGG12072.1 - 0.022 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 PIG-P CAF20 PF17052.5 EGG12073.1 - 3 8.0 8.0 18 5.5 8.0 2.4 1 0 0 1 1 1 0 Cap associated factor Aminotran_1_2 PF00155.21 EGG12076.1 - 1.3e-19 70.7 0.0 4.1e-18 65.7 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II MFS_1 PF07690.16 EGG12077.1 - 2.8e-27 95.6 49.5 5.1e-26 91.4 25.2 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily Flavokinase PF01687.17 EGG12078.1 - 4.5e-28 97.8 0.0 5.9e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Alpha_GJ PF03229.13 EGG12079.1 - 0.00047 20.7 6.1 0.00047 20.7 6.1 2.3 1 1 1 2 2 2 1 Alphavirus glycoprotein J DUF604 PF04646.12 EGG12079.1 - 0.099 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Menin PF05053.13 EGG12079.1 - 0.11 10.9 7.4 0.21 9.9 7.4 1.4 1 0 0 1 1 1 0 Menin FAM60A PF15396.6 EGG12079.1 - 0.74 9.8 2.7 0.42 10.6 0.4 1.7 2 0 0 2 2 2 0 Protein Family FAM60A DUF5580 PF17743.1 EGG12079.1 - 9 4.7 7.7 13 4.1 7.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) PMT PF02366.18 EGG12080.1 - 1.1e-79 267.4 14.0 2.5e-79 266.3 14.0 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGG12080.1 - 1.4e-60 204.3 6.9 1.4e-60 204.3 6.9 3.2 3 0 0 3 3 3 2 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGG12080.1 - 6.4e-20 71.8 2.3 9.3e-20 71.3 0.7 1.8 1 1 1 2 2 2 2 MIR domain DUF1240 PF06836.12 EGG12080.1 - 2.7 8.6 5.5 0.66 10.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) SNF2_N PF00176.23 EGG12083.1 - 1.7e-67 227.7 4.4 8.9e-66 222.0 0.3 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG12083.1 - 1.2e-21 77.1 0.0 5.9e-21 74.9 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EGG12083.1 - 5e-11 42.3 5.2 5.3e-11 42.2 0.0 3.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EGG12083.1 - 2.3e-08 34.2 0.0 2.3e-08 34.2 0.0 3.2 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DnaJ_CXXCXGXG PF00684.19 EGG12084.1 - 0.0011 19.2 7.6 0.0024 18.2 0.5 2.2 2 0 0 2 2 2 2 DnaJ central domain Pkinase PF00069.25 EGG12085.1 - 1.2e-67 228.1 0.0 1.5e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG12085.1 - 7.8e-31 107.3 0.0 1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG12085.1 - 0.0033 16.4 0.0 0.0054 15.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGG12085.1 - 0.019 14.9 0.1 0.042 13.8 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 EGG12085.1 - 0.15 13.0 0.0 0.38 11.7 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat Kdo PF06293.14 EGG12085.1 - 0.18 11.1 0.1 0.43 9.9 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4752 PF15944.5 EGG12087.1 - 0.024 14.7 0.1 0.036 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) Gp_UL130 PF11668.8 EGG12088.1 - 0.095 12.6 0.2 0.14 12.1 0.2 1.2 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 Spexin PF15171.6 EGG12088.1 - 0.11 12.7 2.0 0.42 10.8 0.3 2.4 2 0 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin MADF_DNA_bdg PF10545.9 EGG12088.1 - 4.8 7.6 8.6 0.56 10.6 1.0 3.0 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Ribonuc_P_40 PF08584.11 EGG12091.1 - 4.5e-25 88.5 0.0 9.8e-25 87.4 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit rpo132 PF12415.8 EGG12092.1 - 0.043 13.1 1.8 12 5.3 0.1 4.1 1 1 4 5 5 5 0 Poxvirus DNA dependent RNA polymerase CxC1 PF18802.1 EGG12093.1 - 0.06 13.5 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases CAP59_mtransfer PF11735.8 EGG12097.1 - 1.2e-05 25.1 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ras PF00071.22 EGG12100.1 - 1.7e-09 37.4 0.5 2.1e-08 33.9 0.5 1.9 1 1 0 1 1 1 1 Ras family MATH PF00917.26 EGG12103.1 - 0.045 13.9 0.2 0.074 13.2 0.2 1.4 1 0 0 1 1 1 0 MATH domain Lipase_GDSL PF00657.22 EGG12114.1 - 0.014 15.4 0.0 0.085 12.8 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Lipase_GDSL PF00657.22 EGG12116.1 - 0.002 18.1 0.0 0.0026 17.8 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Snurportin1 PF11538.8 EGG12117.1 - 0.011 15.9 4.5 0.011 15.9 4.5 1.8 2 0 0 2 2 2 0 Snurportin1 Cation_ATPase PF13246.6 EGG12118.1 - 4.7e-11 42.6 0.1 1.5e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Abhydrolase_1 PF00561.20 EGG12119.1 - 5.7e-19 68.8 0.0 4.9e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG12119.1 - 4.3e-17 63.5 0.3 9.2e-17 62.4 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG12119.1 - 8.8e-15 54.6 0.0 2.1e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIP PF03583.14 EGG12119.1 - 0.00094 18.6 0.0 0.0025 17.2 0.0 1.6 2 0 0 2 2 2 1 Secretory lipase PGAP1 PF07819.13 EGG12119.1 - 0.0019 18.0 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 EGG12119.1 - 0.0032 17.3 0.0 0.0079 16.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EGG12119.1 - 0.0062 16.1 0.0 0.018 14.6 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF3530 PF12048.8 EGG12119.1 - 0.009 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) DUF1057 PF06342.12 EGG12119.1 - 0.019 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_8 PF06259.12 EGG12119.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase WD40 PF00400.32 EGG12121.1 - 1.3e-49 165.1 28.9 6.4e-08 33.1 0.2 12.2 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG12121.1 - 2.5e-17 62.9 1.1 0.25 11.7 0.0 7.8 5 3 3 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EGG12121.1 - 2.6e-15 56.6 0.8 4.8e-15 55.8 0.8 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 EGG12121.1 - 3.1e-07 29.4 0.9 0.034 12.8 0.1 4.3 3 1 2 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EGG12121.1 - 1.8e-05 24.2 0.1 0.1 11.9 0.2 3.2 3 2 0 3 3 3 2 WD40-like domain eIF2A PF08662.11 EGG12121.1 - 0.0016 18.4 0.6 0.031 14.1 0.0 2.9 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 EGG12121.1 - 0.044 13.0 3.3 1.4 8.1 0.0 4.2 3 2 2 5 5 5 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ribosomal_L31 PF01197.18 EGG12121.1 - 0.066 13.4 0.1 0.23 11.7 0.1 1.9 1 0 0 1 1 1 0 Ribosomal protein L31 Utp13 PF08625.11 EGG12121.1 - 0.072 13.0 4.0 0.31 11.0 0.5 2.6 2 1 0 2 2 2 0 Utp13 specific WD40 associated domain Hira PF07569.11 EGG12121.1 - 0.11 12.2 0.8 2.1 8.0 0.0 3.1 3 0 0 3 3 3 0 TUP1-like enhancer of split Methyltransf_31 PF13847.6 EGG12122.1 - 4.4e-12 46.0 0.0 6.2e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG12122.1 - 1.1e-08 35.7 0.0 2.1e-08 34.7 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG12122.1 - 1.2e-05 26.0 0.0 1.8e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG12122.1 - 1.2e-05 25.0 0.0 1.7e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EGG12122.1 - 5.7e-05 23.7 0.0 9.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG12122.1 - 0.00025 20.9 0.0 0.00034 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGG12122.1 - 0.00027 20.4 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 EGG12122.1 - 0.0004 20.4 0.0 0.00051 20.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EGG12122.1 - 0.0054 17.0 0.4 0.012 16.0 0.2 1.6 2 0 0 2 2 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 EGG12122.1 - 0.0071 16.0 0.1 0.01 15.4 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 EGG12122.1 - 0.021 13.7 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 EGG12122.1 - 0.028 13.9 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF5010_C PF18099.1 EGG12122.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 DUF5010 C-terminal domain PrmA PF06325.13 EGG12122.1 - 0.18 11.1 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EGG12122.1 - 0.23 10.8 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family YliH PF10799.8 EGG12123.1 - 0.04 13.9 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) Prot_ATP_ID_OB PF16450.5 EGG12126.1 - 0.17 11.9 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain Cation_efflux PF01545.21 EGG12128.1 - 8.9e-19 68.0 4.7 1.2e-18 67.6 4.7 1.2 1 0 0 1 1 1 1 Cation efflux family Cation_efflux PF01545.21 EGG12129.1 - 0.024 14.3 4.3 0.033 13.9 4.3 1.1 1 0 0 1 1 1 0 Cation efflux family WD40 PF00400.32 EGG12131.1 - 7.6e-23 80.4 9.9 0.0011 19.7 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG12131.1 - 4.1e-18 65.5 2.3 1.8e-08 34.6 0.0 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG12131.1 - 0.00026 20.9 0.1 0.0011 18.9 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.16 EGG12132.1 - 5.3e-20 71.6 37.4 2.4e-19 69.5 13.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGG12132.1 - 4.9e-05 22.8 3.8 4.9e-05 22.8 3.8 1.5 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 EGG12132.1 - 0.04 12.8 9.5 0.099 11.5 9.4 1.8 1 1 0 1 1 1 0 Sugar (and other) transporter Glyco_hydro_43 PF04616.14 EGG12133.1 - 3.1e-12 46.4 0.4 6.8e-12 45.3 0.4 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 DUF313 PF03754.13 EGG12134.1 - 0.16 12.2 0.7 1.8 8.8 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF313) Glyco_hydro_43 PF04616.14 EGG12137.1 - 2.6e-07 30.2 0.4 0.0007 19.0 0.1 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 DUF1179 PF06678.11 EGG12139.1 - 0.0013 18.7 2.2 0.0032 17.4 2.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1179) SPATA3 PF15662.5 EGG12139.1 - 1.3 9.6 8.4 2.1 8.9 8.4 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DUF3696 PF12476.8 EGG12141.1 - 0.14 12.6 0.3 0.38 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3696) Peptidase_M17 PF00883.21 EGG12142.1 - 1.1e-118 396.1 0.1 1.4e-118 395.8 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EGG12142.1 - 1.1e-06 28.5 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain RabGAP-TBC PF00566.18 EGG12143.1 - 7.5e-20 71.5 0.9 1.8e-19 70.2 0.9 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Kelch_3 PF13415.6 EGG12144.1 - 6.3e-33 112.4 8.9 1e-09 38.5 0.1 6.8 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EGG12144.1 - 4.5e-25 87.4 9.1 1.5e-07 31.3 0.1 6.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EGG12144.1 - 2.4e-16 59.4 9.8 1.9e-05 24.7 0.1 5.2 2 1 3 5 5 5 3 Kelch motif Kelch_5 PF13854.6 EGG12144.1 - 1.5e-15 56.8 5.9 0.00027 20.8 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EGG12144.1 - 7e-14 51.1 4.0 0.019 14.5 0.1 5.3 5 1 0 5 5 5 4 Kelch motif DUF4110 PF13422.6 EGG12144.1 - 8.4e-14 51.4 1.4 8.4e-14 51.4 1.4 4.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_2 PF07646.15 EGG12144.1 - 6e-11 41.9 7.9 0.0076 16.2 0.2 5.0 4 1 0 4 4 4 3 Kelch motif ACT PF01842.25 EGG12144.1 - 0.12 12.1 0.5 0.39 10.5 0.5 1.9 1 0 0 1 1 1 0 ACT domain Peptidase_S29 PF02907.15 EGG12146.1 - 0.003 17.3 0.0 0.0033 17.2 0.0 1.0 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Rad52_Rad22 PF04098.15 EGG12148.1 - 6.4e-56 188.5 0.0 7.5e-56 188.3 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF2099 PF09872.9 EGG12148.1 - 0.17 11.1 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) Prenyltrans PF00432.21 EGG12150.1 - 4.4e-34 115.9 0.6 9.9e-08 31.6 0.0 6.3 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Alpha_kinase PF02816.18 EGG12152.1 - 4.4e-34 118.2 0.5 4.4e-34 118.2 0.5 3.0 2 1 1 3 3 3 1 Alpha-kinase family SNF2_N PF00176.23 EGG12154.1 - 1.2e-54 185.3 0.0 2.1e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EGG12154.1 - 6.4e-39 134.0 3.7 1.1e-38 133.2 2.6 1.9 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 EGG12154.1 - 4.9e-15 55.8 0.0 9.8e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG12154.1 - 5.1e-08 33.1 0.0 9.9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FmiP_Thoc5 PF09766.9 EGG12154.1 - 0.1 11.8 0.1 0.25 10.6 0.1 1.6 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 EIF_2_alpha PF07541.12 EGG12155.1 - 1.3e-36 125.2 0.0 2.3e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EGG12155.1 - 2.9e-13 49.9 0.9 7e-13 48.7 0.9 1.6 1 0 0 1 1 1 1 S1 RNA binding domain FolB PF02152.18 EGG12156.1 - 0.078 13.5 1.4 0.32 11.6 0.1 2.4 2 0 0 2 2 2 0 Dihydroneopterin aldolase zf-C4H2 PF10146.9 EGG12156.1 - 0.1 12.9 3.3 0.15 12.3 3.3 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Sds3 PF08598.11 EGG12156.1 - 0.23 11.4 6.3 0.34 10.9 5.7 1.6 1 1 0 1 1 1 0 Sds3-like V_ATPase_I PF01496.19 EGG12156.1 - 0.76 7.6 5.3 0.96 7.3 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FOXP-CC PF16159.5 EGG12156.1 - 0.81 10.4 5.1 15 6.3 0.4 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain TSNAXIP1_N PF15739.5 EGG12156.1 - 0.82 10.1 12.9 4 7.9 2.4 2.4 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Mt_ATP-synt_D PF05873.12 EGG12156.1 - 2.1 8.2 6.8 1.5 8.7 2.1 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) FlxA PF14282.6 EGG12156.1 - 2.4 8.2 9.1 5.9 6.9 4.7 2.4 2 0 0 2 2 2 0 FlxA-like protein BST2 PF16716.5 EGG12156.1 - 4.8 7.8 10.4 1.6 9.4 3.2 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 PRKG1_interact PF15898.5 EGG12156.1 - 8.8 7.3 10.2 4.4 8.3 6.7 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Kinesin PF00225.23 EGG12157.1 - 1.7e-82 277.0 0.4 3.1e-75 253.2 0.2 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EGG12157.1 - 2.5e-15 56.7 0.1 1.4e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding LMBR1 PF04791.16 EGG12159.1 - 6.4 5.6 7.7 8.6 5.1 7.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Brr6_like_C_C PF10104.9 EGG12160.1 - 1.3e-41 141.5 6.6 1.4e-41 141.4 6.6 1.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain WD40 PF00400.32 EGG12161.1 - 3.9e-14 52.8 5.3 0.031 15.1 0.2 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG12161.1 - 0.021 15.1 0.0 1.2 9.5 0.0 3.5 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain INCENP_ARK-bind PF03941.15 EGG12162.1 - 8.7e-12 44.8 1.2 8.7e-12 44.8 1.2 2.2 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Adeno_PIX PF03955.14 EGG12162.1 - 1.4 9.1 6.9 1.5 9.0 0.5 3.5 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) SIR2 PF02146.17 EGG12163.1 - 7.6e-56 188.8 0.0 9.1e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family CutC PF03932.14 EGG12163.1 - 0.2 11.1 0.1 0.55 9.7 0.0 1.7 2 0 0 2 2 2 0 CutC family RRM_1 PF00076.22 EGG12168.1 - 1.1e-43 146.9 0.0 6.9e-18 64.2 0.0 4.2 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGG12168.1 - 0.0015 18.5 0.1 0.056 13.5 0.1 2.6 2 1 0 2 2 2 1 Limkain b1 PPTA PF01239.22 EGG12171.1 - 1.9e-34 116.4 12.9 1.4e-08 34.2 0.1 5.2 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat RPN13_C PF16550.5 EGG12171.1 - 0.0027 17.8 0.0 0.23 11.7 0.0 2.2 2 0 0 2 2 2 2 UCH-binding domain PAS_9 PF13426.7 EGG12172.1 - 2.8e-25 88.6 0.0 2.7e-14 53.3 0.0 3.9 4 0 0 4 4 4 3 PAS domain PAS PF00989.25 EGG12172.1 - 9.1e-17 61.1 0.0 1.2e-07 31.7 0.0 4.1 3 1 0 3 3 3 3 PAS fold PAS_3 PF08447.12 EGG12172.1 - 4.7e-15 55.6 0.0 1.1e-08 35.3 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 EGG12172.1 - 1e-07 32.0 0.0 0.00013 22.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 EGG12172.1 - 2.3e-07 31.0 0.0 0.00029 21.1 0.0 3.6 3 0 0 3 3 3 1 PAS fold SIS PF01380.22 EGG12173.1 - 1.1e-59 200.0 0.9 3e-32 111.2 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EGG12173.1 - 1.4e-15 57.7 0.0 2.9e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGG12173.1 - 7e-13 48.6 0.0 1.6e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EGG12173.1 - 0.00011 21.3 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II BCDHK_Adom3 PF10436.9 EGG12174.1 - 2.3e-66 222.6 0.0 3.5e-66 222.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGG12174.1 - 4.6e-14 52.9 0.0 1.8e-12 47.7 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGG12174.1 - 0.00064 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Abhydrolase_1 PF00561.20 EGG12175.1 - 4.2e-20 72.5 0.0 9.2e-20 71.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG12175.1 - 2.6e-17 64.2 0.0 4.5e-17 63.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG12175.1 - 8.9e-13 48.0 0.0 1.6e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 EGG12175.1 - 0.00047 19.3 0.0 0.00082 18.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DLH PF01738.18 EGG12175.1 - 0.024 14.2 0.0 0.071 12.6 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family PGAP1 PF07819.13 EGG12175.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF3530 PF12048.8 EGG12175.1 - 0.22 10.9 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) MCM PF00493.23 EGG12177.1 - 2.7e-75 252.3 3.6 1.6e-62 210.5 1.3 2.2 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 EGG12177.1 - 5e-29 100.7 0.5 1.1e-28 99.6 0.1 1.8 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 EGG12177.1 - 1.4e-10 41.5 0.0 4.1e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGG12177.1 - 3.4e-07 29.9 0.0 7.5e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI MCM6_C PF18263.1 EGG12177.1 - 4.3e-05 23.7 0.4 0.00012 22.3 0.0 1.9 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain Sigma54_activat PF00158.26 EGG12177.1 - 0.031 14.0 0.1 0.058 13.1 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Polyoma_coat2 PF00761.20 EGG12177.1 - 0.13 12.0 0.6 0.32 10.6 0.6 1.6 1 0 0 1 1 1 0 Polyomavirus coat protein SapB_1 PF05184.15 EGG12177.1 - 3 7.9 5.2 1.3 9.1 0.7 2.4 2 0 0 2 2 2 0 Saposin-like type B, region 1 Response_reg PF00072.24 EGG12179.1 - 1.1e-28 99.7 0.0 1.2e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 EGG12180.1 - 1.3e-20 73.6 0.2 1.9e-20 73.1 0.2 1.2 1 0 0 1 1 1 1 Response regulator receiver domain IF4E PF01652.18 EGG12181.1 - 1.1e-19 70.8 0.3 1.4e-19 70.4 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Chitin_synth_2 PF03142.15 EGG12182.1 - 2.2e-16 59.6 0.1 2.5e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glycos_transf_2 PF00535.26 EGG12182.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 PspA_IM30 PF04012.12 EGG12186.1 - 0.099 12.2 4.4 0.12 11.9 4.4 1.1 1 0 0 1 1 1 0 PspA/IM30 family DUF1664 PF07889.12 EGG12186.1 - 0.98 9.5 5.3 2.5 8.1 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Nucleoporin_N PF08801.11 EGG12188.1 - 2.7e-15 56.1 0.0 4.4e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EGG12188.1 - 1.4e-12 47.1 0.2 2e-12 46.7 0.2 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF3404 PF11884.8 EGG12188.1 - 0.1 11.8 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) CDC73_C PF05179.14 EGG12189.1 - 0.00032 20.4 0.1 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal FH2 PF02181.23 EGG12189.1 - 0.042 13.0 0.1 0.063 12.4 0.1 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF16 PF01519.16 EGG12190.1 - 0.053 14.0 1.0 0.91 10.0 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 EGG12190.1 - 0.098 12.7 0.3 0.22 11.6 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 EGG12190.1 - 0.12 12.6 0.5 0.23 11.7 0.3 1.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain JmjC PF02373.22 EGG12195.1 - 0.00036 20.9 0.0 0.0015 19.0 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase NAD_synthase PF02540.17 EGG12196.1 - 0.0085 15.2 0.0 0.0088 15.2 0.0 1.1 1 0 0 1 1 1 1 NAD synthase FAM196 PF15265.6 EGG12197.1 - 0.027 14.0 1.1 0.034 13.6 1.1 1.1 1 0 0 1 1 1 0 FAM196 family DUF572 PF04502.13 EGG12198.1 - 1.7 8.2 28.1 2.1 7.9 28.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PP2C_C PF07830.13 EGG12198.1 - 1.9 9.0 5.9 16 6.0 1.0 2.5 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain CDC45 PF02724.14 EGG12198.1 - 2.7 6.2 24.9 3.7 5.7 24.9 1.3 1 0 0 1 1 1 0 CDC45-like protein SMBP PF16785.5 EGG12198.1 - 3.5 7.9 8.8 0.6 10.3 3.8 2.0 1 1 1 2 2 2 0 Small metal-binding protein RR_TM4-6 PF06459.12 EGG12198.1 - 8.2 6.2 26.0 11 5.8 26.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 EGG12198.1 - 8.6 3.3 23.6 9.9 3.1 23.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NPR3 PF03666.13 EGG12201.1 - 0.15 10.8 4.6 0.19 10.5 4.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ORC6 PF05460.13 EGG12201.1 - 0.25 10.6 8.0 0.34 10.1 8.0 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Presenilin PF01080.17 EGG12201.1 - 4.2 6.0 4.1 4.6 5.9 4.1 1.1 1 0 0 1 1 1 0 Presenilin Histone PF00125.24 EGG12203.1 - 7.4e-39 133.1 1.0 8.3e-39 133.0 1.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGG12203.1 - 3.2e-05 24.0 0.2 4.2e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGG12203.1 - 0.0059 17.0 0.2 0.0083 16.5 0.2 1.3 1 0 0 1 1 1 1 CENP-S protein PilJ PF13675.6 EGG12204.1 - 0.0041 17.1 2.0 0.34 11.0 0.4 2.3 2 0 0 2 2 2 2 Type IV pili methyl-accepting chemotaxis transducer N-term TMF_DNA_bd PF12329.8 EGG12204.1 - 0.0043 17.0 5.6 0.0043 17.0 5.6 3.3 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding FlgO PF17680.1 EGG12204.1 - 0.089 12.5 0.3 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 FlgO protein APG6_N PF17675.1 EGG12204.1 - 0.44 11.1 12.7 0.097 13.2 6.2 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region CC2-LZ PF16516.5 EGG12204.1 - 1.5 9.2 15.0 14 6.2 0.6 3.3 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4363 PF14276.6 EGG12204.1 - 2.8 8.1 6.6 0.81 9.8 0.9 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) Vezatin PF12632.7 EGG12205.1 - 3.4e-11 43.0 0.1 2.6e-05 23.7 0.0 3.5 4 0 0 4 4 4 2 Mysoin-binding motif of peroxisomes NMD3 PF04981.13 EGG12206.1 - 6.5e-80 268.1 2.6 1e-79 267.4 2.6 1.3 1 0 0 1 1 1 1 NMD3 family NinF PF05810.12 EGG12206.1 - 0.0094 15.8 0.4 0.27 11.1 0.2 2.6 2 0 0 2 2 2 1 NinF protein DZR PF12773.7 EGG12206.1 - 0.053 13.6 6.8 3.1 7.9 6.8 2.8 1 1 0 1 1 1 0 Double zinc ribbon GcpE PF04551.14 EGG12206.1 - 0.16 11.0 0.3 0.29 10.2 0.3 1.3 1 0 0 1 1 1 0 GcpE protein Dsl1_C PF11989.8 EGG12207.1 - 3.5e-08 33.4 0.1 4e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal YyzF PF14116.6 EGG12207.1 - 0.034 14.2 0.1 0.057 13.5 0.1 1.3 1 0 0 1 1 1 0 YyzF-like protein DUF5359 PF17313.2 EGG12208.1 - 0.092 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5359) DEAD PF00270.29 EGG12210.1 - 1.2e-38 132.6 0.0 2.3e-38 131.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 EGG12210.1 - 2e-20 72.8 0.2 4e-20 71.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 EGG12210.1 - 1.8e-17 63.7 0.0 9.8e-17 61.3 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG12210.1 - 7.8e-06 26.0 0.0 1.9e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Spt20 PF12090.8 EGG12214.1 - 6.9e-27 94.6 0.0 6.9e-27 94.6 0.0 4.1 3 1 0 3 3 3 2 Spt20 family DUF2956 PF11169.8 EGG12214.1 - 3.2 8.0 16.2 4 7.7 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) zf-RING_2 PF13639.6 EGG12215.1 - 7e-11 42.3 13.2 1.3e-10 41.4 13.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGG12215.1 - 4.1e-07 29.6 7.7 4.1e-07 29.6 7.7 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGG12215.1 - 6.6e-07 29.1 11.8 1.2e-06 28.2 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGG12215.1 - 1.1e-06 28.8 12.9 2.7e-06 27.6 12.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGG12215.1 - 1.5e-05 24.9 15.7 2.4e-05 24.2 15.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG12215.1 - 5.5e-05 23.1 3.4 5.5e-05 23.1 3.4 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG12215.1 - 0.00046 20.0 12.7 0.00088 19.1 12.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG12215.1 - 0.0056 16.5 14.2 0.0094 15.8 14.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGG12215.1 - 0.006 16.6 6.1 0.012 15.7 6.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 EGG12215.1 - 0.077 12.8 7.7 0.17 11.8 7.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 EGG12215.1 - 0.13 11.9 13.9 0.23 11.1 13.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EGG12215.1 - 0.17 11.7 10.8 0.38 10.7 10.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EGG12215.1 - 1.6 9.0 10.9 4.6 7.5 10.9 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_RING PF05883.11 EGG12215.1 - 1.8 8.6 4.5 3 7.8 4.5 1.2 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_6 PF14835.6 EGG12215.1 - 2.4 8.1 7.6 4.9 7.1 7.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein CBF PF03914.17 EGG12216.1 - 3.1e-34 118.4 1.9 2.2e-33 115.7 0.2 2.0 1 1 1 2 2 2 2 CBF/Mak21 family MoCF_biosynth PF00994.24 EGG12217.1 - 1.7e-28 99.1 0.0 3.1e-28 98.2 0.0 1.4 1 1 0 1 1 1 1 Probable molybdopterin binding domain WD40 PF00400.32 EGG12219.1 - 2.1e-12 47.4 2.4 1.2 10.1 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat UPF0370 PF13980.6 EGG12220.1 - 2.2 8.4 5.1 15 5.7 4.1 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) Rep_fac-A_3 PF08661.11 EGG12222.1 - 2.7e-25 88.7 0.0 3.3e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Mt_ATP-synt_B PF05405.14 EGG12223.1 - 4.9e-46 156.3 6.3 5.7e-46 156.1 6.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Mis12 PF05859.12 EGG12223.1 - 0.0089 16.1 1.0 0.012 15.6 1.0 1.2 1 0 0 1 1 1 1 Mis12 protein DUF2461 PF09365.10 EGG12223.1 - 0.019 14.9 0.3 0.036 14.0 0.1 1.5 1 1 0 1 1 1 0 Conserved hypothetical protein (DUF2461) FlxA PF14282.6 EGG12223.1 - 0.15 12.1 0.5 0.36 10.8 0.6 1.6 1 1 0 1 1 1 0 FlxA-like protein SapB_1 PF05184.15 EGG12223.1 - 0.34 11.0 2.9 5.2 7.2 0.2 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 Fib_alpha PF08702.10 EGG12223.1 - 1.9 8.7 4.9 7.6 6.7 1.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CUT PF02376.15 EGG12224.1 - 0.053 13.7 0.4 0.082 13.1 0.3 1.4 1 1 0 1 1 1 0 CUT domain SH3_1 PF00018.28 EGG12225.1 - 1.8e-15 56.3 1.8 9.8e-07 28.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain RA PF00788.23 EGG12225.1 - 7e-10 39.4 0.2 1.5e-09 38.3 0.2 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_9 PF14604.6 EGG12225.1 - 3.2e-09 36.5 0.6 1.5e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 EGG12225.1 - 3.7e-07 29.7 0.3 0.0054 16.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SAM_2 PF07647.17 EGG12225.1 - 4.6e-07 29.8 0.0 1.2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGG12225.1 - 0.00042 20.7 0.1 0.00083 19.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RNA_binding PF01877.17 EGG12226.1 - 0.033 14.5 1.7 0.042 14.1 0.4 1.7 2 0 0 2 2 2 0 RNA binding DUF5508 PF17621.2 EGG12226.1 - 0.049 12.8 0.4 0.069 12.3 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5508) DUF445 PF04286.12 EGG12226.1 - 0.3 10.9 2.9 0.32 10.8 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) PI3Ka PF00613.20 EGG12227.1 - 1.2e-48 164.9 0.0 1.9e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGG12227.1 - 2.9e-41 141.9 0.2 7.9e-28 97.9 0.0 3.1 3 1 1 4 4 4 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EGG12227.1 - 2.9e-19 69.4 0.0 4.7e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 cEGF PF12662.7 EGG12228.1 - 0.022 14.7 0.9 0.1 12.6 0.9 2.2 1 0 0 1 1 1 0 Complement Clr-like EGF-like WD40 PF00400.32 EGG12229.1 - 7.5e-11 42.4 7.3 0.057 14.3 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Caps_synth_GfcC PF06251.11 EGG12230.1 - 0.054 13.1 0.3 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 Capsule biosynthesis GfcC DUF1727 PF08353.10 EGG12230.1 - 0.14 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) Tropomyosin PF00261.20 EGG12231.1 - 0.091 12.1 0.2 0.14 11.5 0.2 1.2 1 0 0 1 1 1 0 Tropomyosin Spc29 PF17082.5 EGG12231.1 - 1.3 8.8 7.1 4.1 7.2 3.0 2.9 2 1 0 2 2 2 0 Spindle Pole Component 29 DMAP_binding PF06464.11 EGG12232.1 - 0.055 14.3 0.3 0.11 13.3 0.3 1.5 1 1 0 1 1 1 0 DMAP1-binding Domain Ribosomal_S5 PF00333.20 EGG12233.1 - 1.8e-21 75.8 0.3 3.3e-21 75.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGG12233.1 - 4e-17 61.4 0.1 1.1e-16 60.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Glyco_hydro_76 PF03663.14 EGG12234.1 - 8.7e-50 170.3 7.9 1.1e-49 170.0 7.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RPAP1_N PF08621.10 EGG12235.1 - 2.2e-08 33.7 3.4 7e-08 32.1 3.4 1.9 1 0 0 1 1 1 1 RPAP1-like, N-terminal RPAP1_C PF08620.10 EGG12235.1 - 0.0045 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal BCIP PF13862.6 EGG12237.1 - 4.7e-55 186.6 0.4 6.4e-55 186.1 0.4 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PSI_integrin PF17205.3 EGG12238.1 - 0.37 10.6 9.3 0.73 9.6 8.2 1.9 1 1 1 2 2 2 0 Integrin plexin domain Tim44 PF04280.15 EGG12240.1 - 1.5e-06 28.4 0.0 3.8e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Tim44-like domain RRF PF01765.19 EGG12240.1 - 0.068 13.1 1.3 0.13 12.2 1.3 1.4 1 0 0 1 1 1 0 Ribosome recycling factor tRNA_bind PF01588.20 EGG12244.1 - 2.4e-27 94.9 0.1 3.9e-27 94.2 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.6 EGG12244.1 - 1.6e-05 25.0 0.0 3.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGG12244.1 - 0.0078 16.0 0.2 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 EGG12245.1 - 2.5e-62 210.6 0.0 3.1e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG12245.1 - 4.7e-34 117.8 0.0 6.4e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG12245.1 - 0.00011 21.3 0.0 0.00022 20.3 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGG12245.1 - 0.0011 18.4 0.1 0.0031 16.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EGG12245.1 - 0.0012 18.5 0.0 0.61 9.7 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 NECFESHC PF16621.5 EGG12245.1 - 0.029 14.3 0.5 0.08 12.9 0.5 1.7 1 0 0 1 1 1 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 LSM PF01423.22 EGG12248.1 - 0.061 13.0 0.1 0.18 11.5 0.1 1.9 1 0 0 1 1 1 0 LSM domain Gly_transf_sug PF04488.15 EGG12249.1 - 1e-08 35.7 0.0 2.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EGG12249.1 - 2.5e-05 23.8 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 EGG12249.1 - 0.00012 21.5 0.1 0.0002 20.8 0.1 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain DUF1752 PF08550.10 EGG12251.1 - 1.6e-11 43.8 3.3 3.3e-11 42.8 3.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF5636 PF18686.1 EGG12251.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5636) Rft-1 PF04506.13 EGG12253.1 - 1.2e-112 377.3 17.5 1.6e-112 376.9 17.5 1.0 1 0 0 1 1 1 1 Rft protein Ank_2 PF12796.7 EGG12254.1 - 2e-11 44.3 0.1 1.4e-06 28.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG12254.1 - 3.9e-11 43.2 0.5 0.00048 20.6 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGG12254.1 - 4.6e-09 36.3 0.8 0.0043 17.4 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EGG12254.1 - 4.1e-08 32.9 1.5 0.016 15.7 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGG12254.1 - 6.5e-07 29.5 0.4 0.036 14.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DEAD PF00270.29 EGG12255.1 - 1.4e-43 148.7 0.4 2.3e-43 148.0 0.4 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG12255.1 - 2.8e-27 95.3 4.3 1.4e-26 93.0 0.6 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 EGG12255.1 - 0.0047 16.3 0.1 0.01 15.2 0.1 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SOG2 PF10428.9 EGG12255.1 - 9.3 5.3 9.4 13 4.8 9.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3682 PF12446.8 EGG12257.1 - 0.2 12.1 5.7 0.27 11.7 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) ADH_zinc_N PF00107.26 EGG12258.1 - 8e-12 45.3 0.0 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGG12258.1 - 0.0046 18.0 0.0 0.0082 17.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG12258.1 - 0.035 14.0 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain COX_ARM PF06481.14 EGG12259.1 - 0.1 12.5 0.2 0.55 10.2 0.1 2.1 2 0 0 2 2 2 0 COX Aromatic Rich Motif ALIX_LYPXL_bnd PF13949.6 EGG12260.1 - 0.027 13.8 2.8 0.038 13.3 2.8 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF702 PF05142.12 EGG12262.1 - 3.1 8.3 6.8 7.6 7.0 6.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Alpha_kinase PF02816.18 EGG12265.1 - 1.9e-06 28.1 0.0 2.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Ribosomal_L21p PF00829.21 EGG12268.1 - 4.1e-17 62.3 0.5 5e-17 62.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein A_deamin PF02137.18 EGG12269.1 - 1.1e-47 163.1 0.0 6.8e-44 150.7 0.0 2.2 2 0 0 2 2 2 2 Adenosine-deaminase (editase) domain Lipase_GDSL PF00657.22 EGG12270.1 - 0.00077 19.5 0.0 0.00084 19.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FlxA PF14282.6 EGG12270.1 - 0.038 14.0 2.1 0.67 10.0 0.6 2.3 2 0 0 2 2 2 0 FlxA-like protein STALD PF18185.1 EGG12271.1 - 0.0048 16.3 0.9 0.3 10.4 0.1 2.1 2 0 0 2 2 2 2 Sir2- and TIR-associating SLOG family IMP2_N PF18590.1 EGG12272.1 - 0.054 14.0 0.1 15 6.2 0.0 2.6 2 0 0 2 2 2 0 Immune Mapped Protein 2 (IMP2) N-terminal domain Glyco_hydro_16 PF00722.21 EGG12275.1 - 1.9e-08 34.0 0.0 4.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CRAL_TRIO_2 PF13716.6 EGG12276.1 - 0.11 12.6 0.4 1.7 8.8 0.2 2.4 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain CxC1 PF18802.1 EGG12281.1 - 2.7e-31 107.8 0.3 1.2e-30 105.7 0.1 2.0 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG12281.1 - 8e-05 22.8 0.2 0.00026 21.1 0.1 1.8 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGG12281.1 - 0.0024 17.5 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Methyltransf_11 PF08241.12 EGG12282.1 - 1.4e-09 38.5 0.0 2.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG12282.1 - 7.1e-08 33.1 0.0 1.2e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG12282.1 - 4.7e-05 23.3 0.0 7.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG12282.1 - 0.0018 18.1 0.0 0.26 11.1 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG12282.1 - 0.004 17.9 0.0 0.045 14.5 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGG12282.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 EGG12282.1 - 0.07 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 EGG12282.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase p450 PF00067.22 EGG12283.1 - 1.9e-58 198.3 0.0 2.3e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 EGG12284.1 - 1.8e-42 142.5 9.9 7.1e-09 36.2 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG12284.1 - 2.1e-16 60.0 0.0 0.0086 16.3 0.0 6.1 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 EGG12284.1 - 1.2e-11 44.0 5.7 2.1e-11 43.1 5.7 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like WD40_like PF17005.5 EGG12284.1 - 1.1e-06 28.3 0.0 0.00072 19.0 0.0 2.6 1 1 1 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 EGG12284.1 - 0.0043 16.1 0.0 0.21 10.5 0.0 3.0 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CENP-B_dimeris PF09026.10 EGG12284.1 - 0.017 15.5 1.2 0.035 14.5 1.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nbas_N PF15492.6 EGG12284.1 - 0.026 13.9 0.1 2.9 7.1 0.0 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EGG12284.1 - 0.31 9.6 2.6 16 3.9 0.0 3.6 2 2 3 5 5 5 0 Nucleoporin Nup120/160 zf-H2C2_5 PF13909.6 EGG12285.1 - 0.0026 17.5 2.7 0.0069 16.1 2.7 1.7 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EGG12285.1 - 0.023 15.2 3.7 0.046 14.2 3.7 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG12285.1 - 0.068 14.0 2.1 0.21 12.5 2.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-MYST PF17772.1 EGG12285.1 - 0.091 12.4 0.3 0.25 11.0 0.3 1.7 1 0 0 1 1 1 0 MYST family zinc finger domain MBOAT_2 PF13813.6 EGG12286.1 - 2e-12 47.2 0.8 2.8e-12 46.7 0.8 1.3 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family GCM PF03615.15 EGG12287.1 - 0.04 13.8 3.7 0.11 12.3 3.7 1.8 1 0 0 1 1 1 0 GCM motif protein DUF3987 PF13148.6 EGG12287.1 - 0.11 11.4 0.7 0.26 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) p450 PF00067.22 EGG12289.1 - 3.8e-54 184.2 0.0 4.7e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dynamin_M PF01031.20 EGG12290.1 - 1.3e-106 356.0 0.9 2e-106 355.4 0.2 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EGG12290.1 - 3e-53 180.3 0.1 5.6e-53 179.5 0.1 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EGG12290.1 - 1.5e-27 95.5 0.0 3.6e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGG12290.1 - 0.00024 21.2 0.1 0.0016 18.5 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase TipAS PF07739.13 EGG12290.1 - 0.073 13.6 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain zf-C2H2 PF00096.26 EGG12291.1 - 0.0095 16.3 1.8 0.032 14.7 1.8 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type MS_channel PF00924.18 EGG12294.1 - 5.1e-17 62.1 1.0 1.3e-16 60.8 1.0 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 EGG12294.1 - 7.8e-09 34.8 1.1 0.0001 21.9 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGG12294.1 - 2e-08 33.2 2.8 3e-05 23.2 0.8 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGG12294.1 - 2.2e-08 34.4 0.4 0.0083 16.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG12294.1 - 7.8e-05 22.0 1.5 0.0036 16.7 0.5 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGG12294.1 - 0.015 15.1 1.7 0.093 12.6 0.3 2.4 1 1 1 2 2 2 0 EF-hand domain pair DUF1724 PF08350.10 EGG12294.1 - 0.056 13.6 0.2 1.5 9.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1724) MSC PF09402.10 EGG12294.1 - 0.1 12.0 1.7 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain EspB_PE PF18625.1 EGG12294.1 - 0.39 11.2 2.7 23 5.6 0.3 2.7 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain E1-E2_ATPase PF00122.20 EGG12294.1 - 1.1 8.8 6.2 7.9 6.0 0.0 3.3 3 0 0 3 3 3 0 E1-E2 ATPase YL1 PF05764.13 EGG12294.1 - 2.5 8.2 18.0 0.67 10.0 9.2 2.4 2 0 0 2 2 2 0 YL1 nuclear protein Ank_2 PF12796.7 EGG12296.1 - 3.4e-09 37.2 0.0 1.9e-08 34.8 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG12296.1 - 1.3e-06 28.8 0.1 4.9e-06 27.0 0.0 2.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EGG12296.1 - 8.3e-06 26.0 0.5 0.0017 18.7 0.2 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EGG12296.1 - 1.6e-05 24.9 0.2 0.011 16.2 0.2 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EGG12296.1 - 3.6e-05 24.0 0.4 0.0056 17.0 0.1 3.1 1 1 1 3 3 3 1 Ankyrin repeats (many copies) NLRC4_HD PF17889.1 EGG12296.1 - 0.03 14.7 0.3 0.068 13.5 0.1 1.6 2 0 0 2 2 2 0 NLRC4 helical domain GCM PF03615.15 EGG12299.1 - 0.11 12.4 2.7 0.38 10.6 2.7 1.9 1 1 0 1 1 1 0 GCM motif protein GIT1_C PF12205.8 EGG12300.1 - 0.019 15.0 1.1 0.083 13.0 0.0 2.2 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Transket_pyr PF02779.24 EGG12303.1 - 3.7e-67 225.5 0.0 1.3e-66 223.6 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EGG12303.1 - 2.9e-58 197.2 0.0 4.5e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EGG12303.1 - 2.6e-48 163.6 0.0 4.6e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EGG12303.1 - 2.4e-17 62.2 0.5 2.4e-17 62.2 0.5 2.0 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Glyco_hydro_47 PF01532.20 EGG12305.1 - 2.2e-141 471.9 0.0 2.5e-141 471.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CxC5 PF18718.1 EGG12306.1 - 2.2e-32 111.6 4.4 2.2e-32 111.6 4.4 2.2 3 0 0 3 3 3 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG12306.1 - 3.8e-20 71.9 1.0 1.2e-19 70.4 1.0 1.9 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases Kunitz_BPTI PF00014.23 EGG12306.1 - 0.045 14.0 0.1 0.19 12.0 0.1 2.1 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain CxC4 PF18717.1 EGG12306.1 - 2.7 7.9 5.8 0.37 10.6 0.7 2.2 2 0 0 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases Thioredoxin PF00085.20 EGG12307.1 - 1.3e-26 92.6 1.9 4.2e-22 78.1 0.2 2.5 1 1 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EGG12307.1 - 2.4e-09 37.6 1.9 1.9e-07 31.5 0.1 2.9 1 1 2 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGG12307.1 - 1e-05 25.6 0.0 3.2e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EGG12307.1 - 5.5e-05 23.4 0.2 0.0078 16.5 0.0 2.8 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 EGG12307.1 - 0.00026 20.4 0.6 0.0017 17.7 0.3 2.2 1 1 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EGG12307.1 - 0.00044 20.2 0.4 0.012 15.5 0.1 2.2 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EGG12307.1 - 0.0093 15.7 0.8 0.22 11.3 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin STT3 PF02516.14 EGG12308.1 - 6.9e-139 463.9 38.2 1e-137 460.0 38.2 2.3 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DUF1149 PF06619.11 EGG12311.1 - 0.49 10.7 3.4 0.93 9.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1149) RPAP2_Rtr1 PF04181.13 EGG12312.1 - 1.2e-15 57.6 0.4 1.2e-15 57.6 0.4 1.7 2 0 0 2 2 2 1 Rtr1/RPAP2 family zf-FCS PF06467.14 EGG12312.1 - 0.00095 19.1 0.2 0.0022 17.9 0.2 1.6 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif LRR_4 PF12799.7 EGG12313.1 - 0.0041 17.5 13.6 13 6.3 0.6 6.4 2 1 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG12317.1 - 0.12 12.2 7.3 18 5.2 1.1 4.9 4 1 0 4 4 4 0 Leucine rich repeat DUF3987 PF13148.6 EGG12318.1 - 1.8 7.5 14.0 2.2 7.2 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Rx_N PF18052.1 EGG12318.1 - 9 6.6 10.7 0.73 10.2 4.1 2.5 2 1 1 3 3 3 0 Rx N-terminal domain LRR_8 PF13855.6 EGG12320.1 - 1.6e-05 24.6 2.2 1.1 9.1 0.4 5.1 5 0 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 EGG12320.1 - 0.00016 22.0 12.0 0.088 13.3 0.0 5.6 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) Gal_mutarotas_2 PF13802.6 EGG12322.1 - 5.8e-08 32.9 0.2 8.6e-08 32.4 0.2 1.4 1 1 0 1 1 1 1 Galactose mutarotase-like Spermine_synth PF01564.17 EGG12323.1 - 1.3e-57 194.3 0.0 2.1e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EGG12323.1 - 3.2e-19 68.6 0.0 5e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EGG12323.1 - 0.0038 17.9 0.0 0.0073 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG12323.1 - 0.016 15.9 0.0 0.043 14.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Sacchrp_dh_C PF16653.5 EGG12324.1 - 1.6e-29 103.8 0.0 3.5e-27 96.2 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain zf-CCHC_6 PF15288.6 EGG12326.1 - 0.55 10.1 2.2 1.1 9.2 2.2 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF2634 PF10934.8 EGG12327.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) SAM_Exu PF18609.1 EGG12328.1 - 0.16 12.1 0.2 0.63 10.2 0.0 1.9 2 0 0 2 2 2 0 Exuperantia SAM-like domain DUF3240 PF11582.8 EGG12329.1 - 0.13 12.4 0.0 5.6 7.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3240) AFT PF08731.11 EGG12330.1 - 0.083 13.3 0.1 0.083 13.3 0.1 2.8 3 0 0 3 3 3 0 Transcription factor AFT DUF4551 PF15087.6 EGG12332.1 - 7.9 5.2 9.6 1.1 8.0 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) LRR_4 PF12799.7 EGG12333.1 - 0.018 15.5 7.2 7.8 7.1 0.2 4.5 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGG12335.1 - 9.7e-05 22.2 0.1 0.035 14.0 0.0 2.6 2 0 0 2 2 2 2 F-box-like MitMem_reg PF13012.6 EGG12336.1 - 4.1e-26 91.6 5.8 4.1e-26 91.6 5.8 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGG12336.1 - 1.6e-12 47.5 0.3 1.8e-11 44.0 0.0 2.6 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Phage_pRha PF09669.10 EGG12336.1 - 0.16 12.5 2.1 0.21 12.2 0.2 2.2 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) F-box-like PF12937.7 EGG12337.1 - 5.5e-07 29.4 0.1 1.3e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG12337.1 - 0.0037 17.1 1.2 0.045 13.6 1.2 2.6 1 1 0 1 1 1 1 F-box domain TPT PF03151.16 EGG12339.1 - 7.3e-38 130.6 16.1 1e-37 130.1 16.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EGG12339.1 - 1.5e-12 47.4 19.0 3.1e-12 46.3 19.0 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGG12339.1 - 1.4e-10 41.5 29.2 6.1e-06 26.4 10.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF3683 PF12447.8 EGG12340.1 - 0.0012 19.0 0.2 0.002 18.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3683) Ferritin_2 PF13668.6 EGG12341.1 - 1.5e-42 145.0 0.1 4e-42 143.6 0.1 1.7 2 0 0 2 2 2 1 Ferritin-like domain Rubrerythrin PF02915.17 EGG12341.1 - 0.025 15.0 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 Rubrerythrin Ferritin PF00210.24 EGG12341.1 - 0.038 13.9 0.0 0.088 12.7 0.0 1.6 2 0 0 2 2 2 0 Ferritin-like domain Ferritin_2 PF13668.6 EGG12342.1 - 1.9e-43 147.9 0.0 2.7e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 EGG12342.1 - 0.0089 16.4 0.1 0.017 15.5 0.1 1.4 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 EGG12342.1 - 0.038 13.9 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain Ferritin_2 PF13668.6 EGG12344.1 - 1.4e-43 148.4 0.6 2e-43 147.8 0.6 1.3 1 0 0 1 1 1 1 Ferritin-like domain Phage_TAC_11 PF11836.8 EGG12344.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Phage tail tube protein, GTA-gp10 Ferritin PF00210.24 EGG12344.1 - 0.078 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like domain Rubrerythrin PF02915.17 EGG12344.1 - 0.16 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Rubrerythrin Smoothelin PF12510.8 EGG12345.1 - 0.0071 16.4 0.4 0.016 15.2 0.4 1.6 1 0 0 1 1 1 1 Smoothelin cytoskeleton protein U3_assoc_6 PF08640.11 EGG12345.1 - 0.063 13.4 0.9 3.9 7.6 0.1 2.2 1 1 1 2 2 2 0 U3 small nucleolar RNA-associated protein 6 DUF4554 PF15091.6 EGG12345.1 - 0.12 11.2 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) TPT PF03151.16 EGG12346.1 - 6.4e-59 199.7 15.8 2.8e-58 197.6 15.8 1.8 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGG12346.1 - 6.8e-16 58.7 30.8 9e-09 35.6 14.3 2.7 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 EGG12346.1 - 1.5e-08 34.2 25.1 1e-05 24.9 8.1 2.1 2 0 0 2 2 2 2 UAA transporter family DUF3262 PF11660.8 EGG12346.1 - 0.3 11.5 0.2 0.3 11.5 0.2 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3262) RPN6_N PF18055.1 EGG12347.1 - 1.2e-35 122.4 1.5 1.2e-35 122.4 1.5 2.3 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EGG12347.1 - 4.8e-18 65.6 0.2 4.8e-18 65.6 0.2 2.6 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 EGG12347.1 - 4.1e-07 29.6 0.0 9.6e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 EGG12347.1 - 0.0001 22.1 0.2 2.4 8.4 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG12347.1 - 0.017 15.4 2.0 20 5.5 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGG12347.1 - 0.028 14.3 1.2 6.8 6.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.12 EGG12349.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Histone PF00125.24 EGG12352.1 - 6.1e-18 65.4 0.0 8.1e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGG12352.1 - 1.4e-17 63.1 0.9 2.7e-17 62.2 0.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGG12352.1 - 9.8e-06 25.8 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Alpha_kinase PF02816.18 EGG12353.1 - 8.1e-31 107.6 0.8 8.1e-31 107.6 0.8 2.6 2 1 0 2 2 2 1 Alpha-kinase family DUF3584 PF12128.8 EGG12353.1 - 0.00024 18.8 0.1 0.00024 18.8 0.1 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Histone PF00125.24 EGG12354.1 - 3.8e-24 85.5 0.6 4.5e-24 85.3 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGG12354.1 - 1.4e-05 25.3 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGG12354.1 - 0.0039 17.6 0.0 0.0058 17.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A BEX PF04538.12 EGG12354.1 - 0.087 13.4 2.2 0.13 12.9 2.2 1.3 1 0 0 1 1 1 0 Brain expressed X-linked like family CENP-W PF15510.6 EGG12354.1 - 0.097 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 CENP-W protein Plus-3 PF03126.18 EGG12355.1 - 1e-21 77.5 0.4 1e-21 77.5 0.4 2.0 2 0 0 2 2 2 1 Plus-3 domain Ribosomal_60s PF00428.19 EGG12356.1 - 6e-26 90.9 8.9 6.8e-26 90.7 8.9 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein ANAPC4_WD40 PF12894.7 EGG12357.1 - 2.4e-09 37.4 0.0 0.0019 18.4 0.0 5.2 6 0 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG12357.1 - 9e-07 29.5 4.6 0.021 15.7 0.0 6.0 6 0 0 6 6 6 1 WD domain, G-beta repeat IKI3 PF04762.12 EGG12357.1 - 0.011 13.7 0.0 3.2 5.6 0.0 3.3 4 0 0 4 4 4 0 IKI3 family PHD PF00628.29 EGG12359.1 - 1.1e-09 38.0 4.8 1.8e-09 37.3 4.8 1.4 1 0 0 1 1 1 1 PHD-finger BAH PF01426.18 EGG12359.1 - 1.3e-05 25.0 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 BAH domain C1_1 PF00130.22 EGG12359.1 - 0.057 13.3 0.5 0.057 13.3 0.5 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 EGG12359.1 - 0.14 12.3 6.6 0.74 10.0 6.6 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger zf-RING_2 PF13639.6 EGG12359.1 - 0.5 10.7 4.7 1.4 9.3 4.7 1.9 1 0 0 1 1 1 0 Ring finger domain Prok-RING_1 PF14446.6 EGG12359.1 - 0.6 10.1 6.7 0.086 12.8 2.0 2.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 SurE PF01975.17 EGG12361.1 - 0.0048 16.7 0.0 0.0073 16.1 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Sterol_MT_C PF08498.10 EGG12362.1 - 1.5e-27 95.6 1.9 2.3e-27 95.1 1.9 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EGG12362.1 - 1.4e-18 67.4 0.0 2.5e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG12362.1 - 1.6e-16 60.5 0.0 3.5e-16 59.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG12362.1 - 5.9e-16 59.0 0.0 1.4e-15 57.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 EGG12362.1 - 1.2e-12 47.7 0.2 1.6e-12 47.3 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGG12362.1 - 5.4e-12 45.8 0.0 8.9e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG12362.1 - 1.9e-11 44.6 0.1 6e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG12362.1 - 5.7e-09 35.7 0.0 9.5e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 EGG12362.1 - 6.1e-05 22.6 0.1 0.0001 22.0 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 EGG12362.1 - 0.0002 21.2 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Spermine_synth PF01564.17 EGG12362.1 - 0.00026 20.5 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain MetW PF07021.12 EGG12362.1 - 0.0019 17.8 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EGG12362.1 - 0.0061 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EGG12362.1 - 0.015 15.3 0.1 0.034 14.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_18 PF00704.28 EGG12363.1 - 4.5e-88 296.0 2.0 5.3e-88 295.7 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SNARE_assoc PF09335.11 EGG12364.1 - 3.7e-18 66.1 4.7 6.6e-18 65.3 4.7 1.4 1 0 0 1 1 1 1 SNARE associated Golgi protein Lig_chan PF00060.26 EGG12364.1 - 0.17 11.7 0.8 0.33 10.8 0.1 1.8 2 0 0 2 2 2 0 Ligand-gated ion channel DUF202 PF02656.15 EGG12364.1 - 1.9 9.0 4.8 1.2 9.6 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) UCH PF00443.29 EGG12365.1 - 1.9e-54 184.9 0.0 2.9e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG12365.1 - 1.2e-16 61.2 0.0 1.8e-15 57.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 EGG12365.1 - 2.1e-06 27.9 0.0 4.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain zf-MIZ PF02891.20 EGG12365.1 - 0.0038 17.0 0.1 0.0077 16.0 0.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger MIT PF04212.18 EGG12365.1 - 0.11 12.6 0.4 0.19 11.8 0.4 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Clr2 PF10383.9 EGG12366.1 - 1e-39 136.7 0.1 5.7e-39 134.2 0.0 2.3 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 EGG12366.1 - 5.8e-18 65.5 1.5 2.3e-17 63.6 1.5 2.1 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Rootletin PF15035.6 EGG12366.1 - 0.31 11.0 6.6 0.65 10.0 6.6 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion RRM_1 PF00076.22 EGG12372.1 - 4.8e-11 42.3 0.0 3e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dockerin_1 PF00404.18 EGG12373.1 - 0.14 12.3 0.0 6.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Dockerin type I domain DUF3719 PF12516.8 EGG12374.1 - 0.16 11.7 0.1 1.1 9.0 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3719) Casein_kappa PF00997.18 EGG12375.1 - 0.6 10.2 4.2 1 9.4 4.2 1.3 1 0 0 1 1 1 0 Kappa casein DUF3719 PF12516.8 EGG12376.1 - 0.22 11.3 2.1 0.39 10.5 0.0 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3719) DUF1640 PF07798.11 EGG12377.1 - 3.3e-58 196.6 6.9 3.8e-58 196.4 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.18 EGG12377.1 - 0.012 15.8 6.7 0.058 13.6 6.7 2.1 1 1 0 1 1 1 0 Homeobox associated leucine zipper YojJ PF10372.9 EGG12377.1 - 0.052 13.6 1.8 0.28 11.3 0.6 2.4 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus Mt_ATP-synt_D PF05873.12 EGG12377.1 - 0.082 12.8 0.5 0.14 12.0 0.5 1.3 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) RNase_J_C PF17770.1 EGG12377.1 - 0.6 11.2 2.7 14 6.8 0.1 3.0 2 1 0 2 2 2 0 Ribonuclease J C-terminal domain FlaC_arch PF05377.11 EGG12377.1 - 0.75 10.2 5.1 9.7 6.7 1.5 3.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) MINDY_DUB PF04424.13 EGG12378.1 - 4.3e-28 97.7 0.0 6.9e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase F-box-like PF12937.7 EGG12380.1 - 0.00017 21.4 1.4 0.00017 21.4 1.4 2.5 2 0 0 2 2 2 1 F-box-like NAD_binding_8 PF13450.6 EGG12381.1 - 4e-14 52.6 0.0 7.3e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGG12381.1 - 3e-10 40.0 0.0 3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EGG12381.1 - 6e-05 22.8 0.2 9.8e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGG12381.1 - 0.024 14.6 0.1 0.061 13.3 0.1 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGG12381.1 - 0.026 13.8 0.0 0.029 13.6 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGG12381.1 - 0.079 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EGG12381.1 - 0.11 11.1 0.1 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EGG12381.1 - 0.12 12.9 0.2 0.22 12.1 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGG12381.1 - 0.2 10.9 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RIFIN PF02009.16 EGG12383.1 - 0.19 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 EGG12383.1 - 1.6 8.6 9.4 16 5.4 9.4 2.5 1 1 0 1 1 1 0 TMEM154 protein family Vps5 PF09325.10 EGG12384.1 - 2e-53 181.4 9.7 3e-53 180.8 9.7 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EGG12384.1 - 4.6e-22 78.1 0.0 1.6e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 EGG12384.1 - 0.0013 18.3 0.4 0.026 14.0 0.4 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR_3 PF16746.5 EGG12384.1 - 1.1 8.9 5.8 2.3 7.9 5.8 1.4 1 0 0 1 1 1 0 BAR domain of APPL family Sec8_exocyst PF04048.14 EGG12384.1 - 2.6 7.9 5.2 4.4 7.2 0.3 3.0 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain Asp PF00026.23 EGG12385.1 - 3e-60 204.3 0.3 3.8e-60 203.9 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG12385.1 - 7.5e-10 39.3 1.2 0.00083 19.6 0.9 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGG12385.1 - 0.002 18.7 1.0 0.9 10.2 0.2 3.3 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 EGG12385.1 - 0.12 12.2 0.1 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal SH3_1 PF00018.28 EGG12389.1 - 1.5e-33 114.1 7.0 1.9e-16 59.4 0.1 4.9 5 0 0 5 5 5 3 SH3 domain SH3_9 PF14604.6 EGG12389.1 - 2.5e-32 110.5 9.1 1.2e-14 53.9 0.1 4.9 6 0 0 6 6 6 3 Variant SH3 domain SHD1 PF03983.12 EGG12389.1 - 1.1e-26 92.4 0.0 2.2e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 EGG12389.1 - 3.2e-16 58.7 0.0 1e-07 31.5 0.0 4.1 4 0 0 4 4 4 3 Variant SH3 domain SAM_4 PF18017.1 EGG12389.1 - 6e-06 26.1 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 EGG12389.1 - 0.00079 19.7 1.7 0.74 10.1 0.2 2.7 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_10 PF17902.1 EGG12389.1 - 0.0076 16.3 0.2 0.063 13.3 0.0 2.6 3 0 0 3 3 3 1 SH3 domain DUF1720 PF08226.11 EGG12389.1 - 0.014 15.8 125.5 4e+03 -1.7 1.1 5.9 2 1 0 3 3 3 0 Domain of unknown function (DUF1720) hSH3 PF14603.6 EGG12389.1 - 0.027 14.9 0.0 3.1 8.3 0.0 2.9 2 0 0 2 2 2 0 Helically-extended SH3 domain LRR_4 PF12799.7 EGG12392.1 - 0.0036 17.7 3.2 0.87 10.1 0.3 3.3 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGG12392.1 - 0.004 17.0 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 EGG12392.1 - 0.0086 15.8 0.8 3 7.7 0.0 3.2 3 0 0 3 3 3 2 Leucine rich repeat F-box-like PF12937.7 EGG12395.1 - 0.0037 17.1 0.2 0.0075 16.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EGG12395.1 - 0.034 14.6 0.0 11 6.5 0.2 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGG12396.1 - 0.012 15.5 0.0 0.035 14.0 0.0 1.8 1 1 0 1 1 1 0 F-box-like Cas9_C PF18525.1 EGG12397.1 - 0.018 15.2 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 Cas9 C-terminal domain Pox_Ag35 PF03286.14 EGG12398.1 - 0.008 16.0 2.9 0.013 15.3 2.9 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Flexi_CP_N PF08358.10 EGG12398.1 - 0.0099 15.8 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 2 Carlavirus coat DUF5089 PF17002.5 EGG12398.1 - 0.56 10.0 5.4 1.1 9.1 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) BTB PF00651.31 EGG12399.1 - 0.1 12.8 0.1 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain TLD PF07534.16 EGG12400.1 - 7.3e-32 110.5 2.1 9.6e-32 110.1 2.1 1.2 1 0 0 1 1 1 1 TLD PNRC PF15365.6 EGG12401.1 - 5.2e-07 29.3 7.4 5.2e-07 29.3 7.4 3.8 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif RIX1 PF08167.12 EGG12404.1 - 0.0089 15.8 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis MFS_1 PF07690.16 EGG12405.1 - 2.1e-23 82.8 20.4 9.3e-23 80.7 20.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DuoxA PF10204.9 EGG12405.1 - 0.032 13.3 0.4 0.032 13.3 0.4 2.5 2 0 0 2 2 2 0 Dual oxidase maturation factor TSP_1 PF00090.19 EGG12406.1 - 0.89 9.8 7.0 1.1 9.5 5.3 2.3 1 1 0 1 1 1 0 Thrombospondin type 1 domain Ribophorin_II PF05817.14 EGG12407.1 - 1.6e-25 89.8 0.0 2e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II VraX PF17412.2 EGG12410.1 - 0.0032 17.1 0.0 1.1e+02 2.5 0.0 5.4 6 0 0 6 6 6 0 Family of unknown function ACTL7A_N PF16840.5 EGG12410.1 - 9.4 6.4 12.6 65 3.7 0.1 5.4 6 0 0 6 6 6 0 Actin-like protein 7A N-terminus Rpn3_C PF08375.11 EGG12412.1 - 3.6e-27 94.6 0.2 1.1e-26 93.0 0.1 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EGG12412.1 - 2.2e-21 76.3 0.0 5.6e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 EGG12412.1 - 0.00059 19.8 0.0 0.0022 18.0 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 EGG12412.1 - 0.091 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family TPR_12 PF13424.6 EGG12412.1 - 0.36 11.1 0.1 0.36 11.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-MIZ PF02891.20 EGG12413.1 - 0.92 9.3 15.1 0.49 10.2 0.3 3.8 2 1 1 3 3 3 0 MIZ/SP-RING zinc finger NOA36 PF06524.12 EGG12414.1 - 0.47 9.7 3.2 0.73 9.1 3.2 1.4 1 0 0 1 1 1 0 NOA36 protein PAPA-1 PF04795.12 EGG12414.1 - 0.7 10.7 0.1 0.7 10.7 0.1 3.1 2 1 0 2 2 2 0 PAPA-1-like conserved region CENP-B_dimeris PF09026.10 EGG12414.1 - 3.4 8.1 9.7 5.2 7.5 9.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sec62 PF03839.16 EGG12415.1 - 3.3e-49 167.3 9.7 1.9e-48 164.8 9.7 1.8 1 1 0 1 1 1 1 Translocation protein Sec62 Ost4 PF10215.9 EGG12415.1 - 0.34 10.8 2.4 0.96 9.3 2.4 1.8 1 0 0 1 1 1 0 Oligosaccaryltransferase Glyco_transf_90 PF05686.12 EGG12416.1 - 2.8e-15 56.1 1.0 7.1e-15 54.8 1.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_transf_90 PF05686.12 EGG12417.1 - 7.2e-16 58.1 2.7 3.1e-15 56.0 2.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 90 Cnd1 PF12717.7 EGG12418.1 - 5.2e-48 163.1 16.7 2.5e-47 161.0 0.7 5.0 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 EGG12418.1 - 2.8e-46 157.4 1.9 2.8e-46 157.4 1.9 3.8 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 EGG12418.1 - 3e-07 30.1 0.0 7.2 7.2 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat Cnd3 PF12719.7 EGG12418.1 - 1.4e-05 24.5 9.1 1.5e-05 24.3 1.1 3.9 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EGG12418.1 - 0.0017 18.7 0.0 7 7.1 0.0 4.1 4 0 0 4 4 4 2 HEAT repeats RTP1_C1 PF10363.9 EGG12418.1 - 0.0027 17.9 1.5 10 6.3 0.0 4.9 5 1 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGG12418.1 - 0.0093 16.5 1.0 4.5 7.9 0.0 4.4 5 0 0 5 5 5 1 HEAT-like repeat YtzH PF14165.6 EGG12418.1 - 0.046 14.1 0.5 2.3 8.6 0.0 3.7 3 0 0 3 3 3 0 YtzH-like protein FAM176 PF14851.6 EGG12418.1 - 0.79 9.4 24.5 1.1 9.0 0.1 3.9 3 0 0 3 3 3 0 FAM176 family Ipi1_N PF12333.8 EGG12418.1 - 5.4 7.7 6.8 3.2 8.4 0.5 3.8 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DUF4699 PF15770.5 EGG12419.1 - 0.081 12.7 2.8 0.096 12.4 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) G_path_suppress PF15991.5 EGG12419.1 - 1.3 9.1 5.1 1.6 8.8 5.1 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor Gemini_AL2 PF01440.16 EGG12421.1 - 4.8 7.6 12.2 0.13 12.7 4.1 2.4 1 1 1 3 3 3 0 Geminivirus AL2 protein Zip PF02535.22 EGG12421.1 - 7.7 5.6 4.8 9.4 5.3 4.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Aldedh PF00171.22 EGG12422.1 - 1.2e-177 591.1 0.1 1.3e-177 591.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IPI_T4 PF11634.8 EGG12422.1 - 0.081 12.9 0.2 0.5 10.4 0.0 2.4 3 0 0 3 3 3 0 Nuclease inhibitor from bacteriophage T4 zf-UBR PF02207.20 EGG12423.1 - 3.1e-12 46.5 13.6 3.1e-12 46.5 13.6 3.3 3 0 0 3 3 3 2 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 EGG12423.1 - 0.0004 20.2 6.3 0.0004 20.2 6.3 3.5 2 1 0 3 3 3 1 PHD-finger Swi5 PF07061.11 EGG12423.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Swi5 Dynamin_M PF01031.20 EGG12423.1 - 0.072 12.3 0.5 0.12 11.5 0.5 1.3 1 0 0 1 1 1 0 Dynamin central region PAS_9 PF13426.7 EGG12424.1 - 2.9e-05 24.3 0.0 0.095 13.0 0.0 3.2 2 1 0 2 2 2 2 PAS domain AAA_25 PF13481.6 EGG12425.1 - 2.6e-09 36.9 0.1 3.6e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EGG12425.1 - 0.00031 20.2 0.0 0.0016 17.8 0.0 1.9 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 EGG12425.1 - 0.0015 18.8 0.0 0.003 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGG12425.1 - 0.0052 16.5 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGG12425.1 - 0.015 15.1 0.0 0.033 13.9 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 EGG12425.1 - 0.034 14.6 0.1 0.07 13.5 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EGG12425.1 - 0.04 13.7 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EGG12425.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Aminotran_5 PF00266.19 EGG12429.1 - 1.9e-10 40.3 0.0 9.9e-10 37.9 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Torus PF16131.5 EGG12432.1 - 1.5e-08 35.3 5.3 0.00015 22.4 0.6 2.7 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 EGG12432.1 - 3.5e-05 23.5 7.7 0.0026 17.5 0.6 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGG12432.1 - 6.6e-05 22.8 4.8 6.6e-05 22.8 4.8 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 EGG12432.1 - 9.3e-05 22.2 1.3 9.3e-05 22.2 1.3 2.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EGG12432.1 - 0.0024 18.1 1.2 0.0053 17.0 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGG12432.1 - 1.2 9.7 7.4 0.47 11.0 1.6 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF3519 PF12033.8 EGG12433.1 - 0.065 13.6 0.2 0.065 13.6 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3519) NAD_Gly3P_dh_N PF01210.23 EGG12435.1 - 5.9e-44 149.8 0.1 9.4e-44 149.2 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EGG12435.1 - 8.7e-44 149.2 0.1 1.5e-43 148.5 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EGG12435.1 - 5.2e-05 23.7 0.1 0.32 11.6 0.1 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent DUF587 PF04532.12 EGG12435.1 - 0.013 14.8 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF587) Semialdhyde_dh PF01118.24 EGG12435.1 - 0.049 14.1 0.0 0.22 11.9 0.0 2.1 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF4951 PF16309.5 EGG12435.1 - 0.098 12.7 0.1 1.7 8.8 0.0 2.3 1 1 1 2 2 2 0 Domian of unknown function (DUF4951) PDGF_N PF04692.13 EGG12437.1 - 0.013 16.3 0.8 0.022 15.6 0.1 1.7 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region IFT57 PF10498.9 EGG12438.1 - 0.0023 17.0 2.0 0.0036 16.3 2.0 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 EGG12438.1 - 0.014 15.5 1.7 0.024 14.7 1.7 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Borrelia_REV PF03978.13 EGG12438.1 - 0.017 15.0 2.7 0.033 14.1 2.7 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein OmpH PF03938.14 EGG12438.1 - 0.026 14.8 1.0 0.045 14.1 1.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 EGG12438.1 - 0.03 14.4 0.6 0.03 14.4 0.6 1.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EGG12438.1 - 0.036 14.1 3.0 0.086 12.9 3.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 EGG12438.1 - 0.044 14.3 2.2 0.12 12.8 1.9 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tho2 PF11262.8 EGG12438.1 - 0.081 12.1 1.4 0.13 11.4 1.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FliD_N PF02465.18 EGG12438.1 - 0.093 13.4 2.3 0.58 10.9 2.3 2.2 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Lectin_N PF03954.14 EGG12438.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Spc7 PF08317.11 EGG12438.1 - 0.11 11.3 3.8 0.18 10.7 3.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 EGG12438.1 - 0.72 9.0 2.4 1.2 8.3 2.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein EF-hand_10 PF14788.6 EGG12441.1 - 0.054 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 EF hand DUF3023 PF11224.8 EGG12441.1 - 0.058 13.2 0.0 0.089 12.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3023) Frankia_peptide PF14407.6 EGG12443.1 - 0.00051 20.0 0.4 0.00084 19.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. AMP-binding PF00501.28 EGG12444.1 - 0.0003 19.5 0.0 0.00074 18.2 0.0 1.5 1 1 1 2 2 2 1 AMP-binding enzyme HECT_2 PF09814.9 EGG12444.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Rop-like PF05082.13 EGG12445.1 - 0.0019 18.0 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Rop-like H-kinase_dim PF02895.14 EGG12445.1 - 0.018 15.4 0.6 2.7 8.4 0.1 2.2 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Pet191_N PF10203.9 EGG12445.1 - 0.036 14.4 0.1 0.051 13.9 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Snapin_Pallidin PF14712.6 EGG12445.1 - 0.042 14.3 1.4 0.99 9.9 0.7 2.1 1 1 1 2 2 2 0 Snapin/Pallidin Syntaxin-6_N PF09177.11 EGG12445.1 - 0.073 13.6 0.2 0.1 13.2 0.2 1.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4694 PF15765.5 EGG12446.1 - 0.0091 16.0 0.4 0.021 14.9 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4694) DUF1387 PF07139.11 EGG12446.1 - 0.046 13.5 2.2 0.06 13.1 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) RNA_pol_Rpc82 PF05645.13 EGG12447.1 - 0.18 11.5 6.6 1.5 8.5 6.0 2.3 2 1 0 2 2 2 0 RNA polymerase III subunit RPC82 AT_hook PF02178.19 EGG12447.1 - 6.8 6.9 8.4 0.29 11.1 2.1 2.1 2 0 0 2 2 2 0 AT hook motif CDC45 PF02724.14 EGG12448.1 - 2.4 6.4 20.5 0.06 11.6 13.9 1.6 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 EGG12448.1 - 4.3 6.7 20.6 9.7 5.5 20.6 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGG12448.1 - 7.1 4.7 20.4 12 3.9 20.4 1.3 1 0 0 1 1 1 0 Nop14-like family MIP PF00230.20 EGG12452.1 - 0.00029 20.6 0.4 0.00045 20.0 0.4 1.3 1 1 0 1 1 1 1 Major intrinsic protein Attachment_P66 PF11263.8 EGG12452.1 - 0.18 11.0 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 U3_assoc_6 PF08640.11 EGG12453.1 - 0.068 13.3 3.6 0.31 11.1 0.0 2.4 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Filament PF00038.21 EGG12454.1 - 0.005 16.5 1.8 0.005 16.5 1.8 1.7 1 1 0 1 1 1 1 Intermediate filament protein Tropomyosin PF00261.20 EGG12454.1 - 0.053 12.9 8.6 0.59 9.4 0.6 2.1 1 1 1 2 2 2 0 Tropomyosin Atg14 PF10186.9 EGG12454.1 - 0.072 12.2 2.2 0.073 12.1 2.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 EGG12454.1 - 0.093 13.1 4.1 0.52 10.7 0.3 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain Med9 PF07544.13 EGG12454.1 - 0.094 12.8 1.3 0.13 12.3 0.9 1.6 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.10 EGG12454.1 - 0.13 12.4 3.4 0.18 12.0 3.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 EGG12454.1 - 0.17 11.9 1.9 0.8 9.8 0.1 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Rx_N PF18052.1 EGG12454.1 - 0.35 11.2 4.2 0.54 10.6 1.3 2.6 2 1 0 2 2 2 0 Rx N-terminal domain DS PF01916.17 EGG12455.1 - 8.9e-27 94.1 0.0 5.4e-17 62.0 0.0 2.0 1 1 0 2 2 2 2 Deoxyhypusine synthase Tom37 PF10568.9 EGG12456.1 - 0.022 15.1 0.0 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein 2OG-FeII_Oxy_4 PF13661.6 EGG12456.1 - 0.075 13.7 0.1 0.14 12.8 0.1 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Myb_Cef PF11831.8 EGG12457.1 - 0.43 10.1 3.9 0.72 9.4 1.9 2.0 2 0 0 2 2 2 0 pre-mRNA splicing factor component TauD PF02668.16 EGG12460.1 - 8.1e-33 114.4 0.0 1.3e-32 113.7 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EGG12460.1 - 7.4e-18 65.0 0.0 1.6e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EGG12460.1 - 0.05 12.7 0.0 0.097 11.8 0.0 1.4 1 0 0 1 1 1 0 CsiD DUF2442 PF10387.9 EGG12460.1 - 0.1 12.9 0.0 5.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) 2-oxoacid_dh PF00198.23 EGG12461.1 - 7.8e-80 267.7 0.1 1.1e-79 267.2 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGG12461.1 - 3e-20 71.8 1.0 5.8e-20 70.9 1.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGG12461.1 - 5.7e-06 26.1 0.0 0.048 13.5 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 EGG12461.1 - 0.00062 19.7 0.3 0.0013 18.6 0.3 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.6 EGG12461.1 - 0.0011 19.7 0.1 0.14 12.8 0.0 2.6 1 1 1 2 2 2 1 HlyD family secretion protein baeRF_family11 PF18855.1 EGG12461.1 - 0.061 13.6 0.6 0.22 11.8 0.0 2.3 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 11 PEGSRP PF07623.11 EGG12461.1 - 0.34 10.7 2.5 1.1 9.1 2.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) HlyD_D23 PF16576.5 EGG12461.1 - 1.1 8.4 6.4 0.45 9.7 1.3 2.6 2 1 0 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ELYS PF13934.6 EGG12462.1 - 7.2e-47 160.2 1.2 1.1e-46 159.6 1.2 1.3 1 0 0 1 1 1 1 Nuclear pore complex assembly MutS_V PF00488.21 EGG12463.1 - 6.8e-67 225.2 0.1 1.1e-66 224.5 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGG12463.1 - 1.8e-33 116.4 1.9 4.1e-33 115.2 0.3 2.3 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EGG12463.1 - 5e-30 104.0 0.0 1.2e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EGG12463.1 - 1.2e-09 38.6 0.0 3.6e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EGG12463.1 - 1.2e-06 28.7 0.2 3.2e-06 27.4 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV Metallophos_3 PF14582.6 EGG12463.1 - 0.013 14.8 0.2 0.025 13.9 0.2 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily AAA_29 PF13555.6 EGG12463.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGG12463.1 - 0.096 13.2 6.8 0.29 11.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EGG12464.1 - 1.2e-46 158.7 0.0 1.1e-24 87.5 0.1 2.8 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGG12464.1 - 3.1e-23 81.6 5.1 3.1e-23 81.6 5.1 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGG12464.1 - 2.1e-14 54.0 18.9 9.8e-06 25.6 0.3 4.9 3 2 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG12464.1 - 5.5e-09 35.8 3.5 1.7e-06 27.6 1.3 4.3 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGG12464.1 - 1.1e-06 28.3 0.1 0.015 15.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EGG12464.1 - 1.4e-06 28.4 0.1 0.024 14.6 0.0 3.5 2 1 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 EGG12464.1 - 3.7e-06 27.3 0.1 0.13 12.5 0.0 3.4 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EGG12464.1 - 5e-06 26.6 0.1 0.13 12.3 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGG12464.1 - 7.4e-06 26.4 0.6 0.063 13.7 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGG12464.1 - 1.7e-05 24.8 0.0 0.071 13.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 EGG12464.1 - 0.00057 19.7 0.0 0.94 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGG12464.1 - 0.00064 19.9 0.1 0.72 10.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain MeaB PF03308.16 EGG12464.1 - 0.00087 18.4 0.0 0.5 9.3 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EGG12464.1 - 0.0015 19.1 10.9 0.083 13.4 0.0 4.0 3 1 1 4 4 4 1 AAA domain RNA_helicase PF00910.22 EGG12464.1 - 0.0016 18.8 0.0 0.55 10.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 EGG12464.1 - 0.0026 18.3 0.4 2.6 8.6 0.0 4.0 5 0 0 5 5 3 1 AAA domain AAA_14 PF13173.6 EGG12464.1 - 0.0027 17.8 0.1 2.5 8.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 EGG12464.1 - 0.0082 16.6 0.0 0.79 10.2 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EGG12464.1 - 0.0087 15.8 9.1 0.15 11.7 0.0 3.7 4 1 0 4 4 4 2 AAA ATPase domain DUF87 PF01935.17 EGG12464.1 - 0.023 14.8 3.0 0.7 9.9 0.0 3.3 4 0 0 4 4 3 0 Helicase HerA, central domain SbcCD_C PF13558.6 EGG12464.1 - 0.025 14.8 0.7 1.3 9.3 0.1 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 EGG12464.1 - 0.026 14.5 0.4 17 5.4 0.1 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.15 EGG12464.1 - 0.027 13.3 0.0 2 7.1 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_30 PF13604.6 EGG12464.1 - 0.045 13.5 0.0 2.2 7.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 EGG12464.1 - 0.052 13.8 0.0 9.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EGG12464.1 - 0.1 12.5 0.0 9.9 6.0 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 EGG12464.1 - 0.1 12.8 4.3 4.1 7.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 EGG12464.1 - 0.11 11.7 0.0 10 5.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 EGG12464.1 - 0.11 12.5 0.6 2.5 8.1 0.1 3.1 3 0 0 3 3 3 0 Dynamin family cobW PF02492.19 EGG12464.1 - 0.11 12.0 0.3 3.2 7.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EGG12464.1 - 0.16 11.5 0.0 14 5.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF406 PF04175.12 EGG12464.1 - 1 9.9 3.9 1.9 9.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF406) OPT PF03169.15 EGG12465.1 - 2.8e-44 151.8 32.1 8.4e-31 107.3 5.5 4.9 3 1 1 4 4 4 4 OPT oligopeptide transporter protein CxC6 PF18721.1 EGG12467.1 - 2.8e-20 72.3 1.2 2.8e-20 72.3 1.2 2.1 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases Cyt-b5 PF00173.28 EGG12468.1 - 0.003 17.7 0.1 0.0042 17.2 0.1 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DIM1 PF02966.16 EGG12469.1 - 7.9e-63 210.1 0.0 9.1e-63 209.9 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EGG12469.1 - 6e-05 23.0 0.0 8.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGG12469.1 - 0.0044 17.3 0.1 0.0069 16.7 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EGG12469.1 - 0.085 13.0 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Peroxin-3 PF04882.12 EGG12474.1 - 0.16 11.0 6.6 0.39 9.7 0.3 2.1 2 0 0 2 2 2 0 Peroxin-3 PCMT PF01135.19 EGG12475.1 - 2.6e-60 203.8 0.0 3.9e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EGG12475.1 - 0.00076 19.3 0.0 0.00097 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EGG12475.1 - 0.0027 17.3 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 EGG12475.1 - 0.0038 17.0 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGG12475.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PIG-S PF10510.9 EGG12477.1 - 6.7e-120 401.3 10.2 2.5e-118 396.2 10.2 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein OPT PF03169.15 EGG12478.1 - 3.5e-110 369.5 30.4 6.8e-104 348.7 23.3 2.0 2 0 0 2 2 2 2 OPT oligopeptide transporter protein Phtf-FEM1B_bdg PF12129.8 EGG12479.1 - 0.082 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor TarH PF02203.15 EGG12480.1 - 0.055 13.4 0.0 0.064 13.2 0.0 1.1 1 0 0 1 1 1 0 Tar ligand binding domain homologue Utp21 PF04192.12 EGG12481.1 - 1.9e-55 187.9 0.1 2.8e-55 187.3 0.1 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EGG12481.1 - 5.4e-18 65.0 11.5 0.00085 20.1 0.0 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG12481.1 - 9.7e-15 54.6 0.0 0.26 11.6 0.0 7.5 2 2 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGG12481.1 - 0.001 17.9 0.0 3.5 6.2 0.0 3.3 3 0 0 3 3 3 2 Nup133 N terminal like DUF4384 PF14326.6 EGG12481.1 - 0.0054 16.8 0.0 0.053 13.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4384) VID27 PF08553.10 EGG12481.1 - 0.042 12.9 0.0 0.084 11.9 0.0 1.5 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 EGG12481.1 - 0.14 10.7 0.0 0.53 8.8 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF3421 PF11901.8 EGG12482.1 - 2e-28 98.7 8.6 7.7e-17 61.3 2.1 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF3421) SARAF PF06682.12 EGG12482.1 - 4.8 6.7 10.3 7.1 6.2 10.3 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4276 PF14103.6 EGG12483.1 - 0.29 11.3 3.9 0.31 11.3 3.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) DUF999 PF06198.11 EGG12483.1 - 8.1 6.4 10.0 8.9 6.3 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF999) PROCN PF08083.11 EGG12488.1 - 2.6e-115 385.4 3.3 3.4e-115 385.0 3.3 1.0 1 0 0 1 1 1 1 PROCN (NUC071) domain U5_2-snRNA_bdg PF10597.9 EGG12489.1 - 1.2e-20 74.0 0.5 2.3e-18 66.6 0.5 2.2 1 1 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 CD24 PF14984.6 EGG12493.1 - 3.2 8.1 7.5 3.6 7.9 0.2 2.8 2 1 1 3 3 3 0 CD24 protein RXT2_N PF08595.11 EGG12494.1 - 0.13 12.3 0.4 0.27 11.3 0.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 EGG12494.1 - 5.2 7.5 13.6 9.5 6.7 13.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RhoGAP PF00620.27 EGG12495.1 - 3e-38 131.0 0.5 7.9e-38 129.7 0.2 1.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EGG12495.1 - 4.3e-26 90.9 35.9 2.1e-11 43.9 2.7 5.4 6 0 0 6 6 6 4 LIM domain GM_CSF PF01109.17 EGG12495.1 - 0.041 14.0 0.0 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor OMPdecase PF00215.24 EGG12497.1 - 1.7e-75 253.5 0.0 2.1e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family F-box PF00646.33 EGG12500.1 - 0.072 13.0 4.1 2.4 8.1 0.3 3.6 3 0 0 3 3 3 0 F-box domain Exo_endo_phos PF03372.23 EGG12502.1 - 5.3e-25 88.3 0.1 3.4e-24 85.7 0.1 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 EGG12502.1 - 7.1e-14 51.3 14.8 3.9e-07 29.7 1.1 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EGG12502.1 - 1.3e-11 44.6 2.9 7.8e-06 26.1 0.4 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGG12502.1 - 0.0045 17.3 0.2 55 4.9 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 EGG12502.1 - 0.24 11.6 1.7 0.88 9.8 0.1 2.8 3 0 0 3 3 3 0 Leucine Rich repeat RVT_3 PF13456.6 EGG12504.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like RasGEF PF00617.19 EGG12505.1 - 1.6e-40 139.2 0.0 3.5e-40 138.1 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGG12505.1 - 7.8e-06 26.1 2.6 1.8e-05 24.9 0.4 2.8 2 0 0 2 2 2 1 RasGEF N-terminal motif AAA_16 PF13191.6 EGG12505.1 - 0.016 15.6 0.0 0.1 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EGG12505.1 - 0.14 12.7 0.7 0.73 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Aldedh PF00171.22 EGG12507.1 - 5.7e-130 433.9 0.1 6.4e-130 433.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGG12507.1 - 0.07 12.2 0.0 0.14 11.2 0.0 1.5 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Mito_carr PF00153.27 EGG12508.1 - 5.2e-43 144.9 2.5 8.4e-15 54.5 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein TcpF PF06340.11 EGG12508.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F Asn_synthase PF00733.21 EGG12510.1 - 8.3e-19 68.4 0.2 1.5e-08 34.7 0.0 3.3 2 1 1 3 3 3 3 Asparagine synthase SET PF00856.28 EGG12510.1 - 1.1e-10 42.2 0.6 9.6e-10 39.1 0.6 2.4 1 1 0 1 1 1 1 SET domain GATase_7 PF13537.6 EGG12510.1 - 5e-09 36.1 0.0 1.3e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGG12510.1 - 1.7e-05 25.0 0.0 3.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGG12510.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein HA2 PF04408.23 EGG12511.1 - 4.6e-20 71.9 0.0 4.6e-20 71.9 0.0 3.4 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGG12511.1 - 2.8e-16 59.6 0.0 6.7e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGG12511.1 - 4.1e-14 52.9 0.0 1.1e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG12511.1 - 2.2e-05 24.3 0.0 6.7e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EGG12511.1 - 0.0002 21.1 0.1 0.00046 20.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGG12511.1 - 0.00071 18.7 0.0 0.0019 17.3 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGG12511.1 - 0.00084 19.6 0.0 0.0042 17.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain PWI PF01480.17 EGG12511.1 - 0.0028 17.9 0.0 0.0079 16.5 0.0 1.8 1 0 0 1 1 1 1 PWI domain AAA_19 PF13245.6 EGG12511.1 - 0.0034 17.7 0.1 0.014 15.8 0.1 2.0 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EGG12511.1 - 0.015 14.9 0.1 0.05 13.2 0.1 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF3074 PF11274.8 EGG12512.1 - 9.4e-35 120.3 0.0 1.3e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) ParA PF10609.9 EGG12513.1 - 4.4e-79 265.4 0.0 1.8e-78 263.4 0.0 1.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGG12513.1 - 2.3e-06 27.7 0.0 6e-06 26.3 0.0 1.7 1 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EGG12513.1 - 3.9e-06 26.3 0.0 5.9e-05 22.5 0.0 2.1 1 1 1 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 EGG12513.1 - 0.00044 19.5 0.4 0.0013 18.0 0.4 1.9 1 1 0 1 1 1 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EGG12513.1 - 0.00076 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_31 PF13614.6 EGG12513.1 - 0.001 19.0 0.0 0.0031 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGG12513.1 - 0.037 13.6 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain LRR_4 PF12799.7 EGG12514.1 - 4.1e-08 33.4 2.4 0.068 13.6 0.0 3.4 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG12514.1 - 1e-05 25.2 3.4 0.0053 16.5 0.1 3.4 1 1 3 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 EGG12514.1 - 0.00032 20.5 1.1 3.1 8.1 0.0 4.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 EGG12514.1 - 0.00089 19.5 5.5 39 5.4 0.6 5.9 4 2 0 4 4 4 1 Leucine Rich Repeat DUF1322 PF07032.11 EGG12515.1 - 0.077 13.5 0.1 0.14 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1322) Rib_5-P_isom_A PF06026.14 EGG12519.1 - 4.2e-10 39.5 0.0 5.2e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Arrestin_C PF02752.22 EGG12522.1 - 0.082 13.4 3.0 0.1 13.0 0.5 2.4 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain MLANA PF14991.6 EGG12522.1 - 0.54 10.5 2.9 8.6 6.7 0.3 2.9 2 0 0 2 2 2 0 Protein melan-A AAA PF00004.29 EGG12523.1 - 3.3e-50 169.9 0.0 7.3e-41 139.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG12523.1 - 2e-10 40.3 0.0 5.6e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGG12523.1 - 2.5e-08 34.5 0.0 3.5e-05 24.2 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EGG12523.1 - 2.2e-07 30.8 0.0 2.2e-05 24.2 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 EGG12523.1 - 2.6e-05 24.4 0.0 0.0001 22.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGG12523.1 - 3.7e-05 24.0 1.0 0.1 12.9 0.1 4.4 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EGG12523.1 - 4.6e-05 23.4 0.0 0.011 15.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGG12523.1 - 0.00059 20.2 0.0 0.066 13.6 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 EGG12523.1 - 0.00065 20.3 0.0 0.068 13.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 EGG12523.1 - 0.0014 18.7 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 EGG12523.1 - 0.0023 18.4 0.1 0.1 13.1 0.0 3.0 3 0 0 3 3 2 1 ABC transporter AAA_14 PF13173.6 EGG12523.1 - 0.0042 17.1 0.0 0.44 10.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EGG12523.1 - 0.0073 16.5 0.0 0.029 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGG12523.1 - 0.013 15.0 0.0 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGG12523.1 - 0.013 14.9 0.1 0.1 12.0 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGG12523.1 - 0.015 15.0 0.0 0.98 9.1 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.6 EGG12523.1 - 0.021 15.0 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGG12523.1 - 0.023 14.4 0.1 0.079 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain ResIII PF04851.15 EGG12523.1 - 0.034 14.1 0.0 0.13 12.3 0.0 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EGG12523.1 - 0.038 13.2 0.0 0.22 10.7 0.0 2.2 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EGG12523.1 - 0.039 13.4 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.13 EGG12523.1 - 0.041 13.1 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 EGG12523.1 - 0.043 13.4 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EGG12523.1 - 0.05 13.3 0.1 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Bromodomain PF00439.25 EGG12523.1 - 0.09 12.9 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Bromodomain NACHT PF05729.12 EGG12523.1 - 0.096 12.6 0.0 0.48 10.3 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 EGG12523.1 - 0.1 11.7 0.0 0.39 9.8 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 EGG12523.1 - 0.69 9.6 0.0 0.69 9.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain HECT PF00632.25 EGG12524.1 - 2.2e-75 254.0 0.0 2.9e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Es2 PF09751.9 EGG12527.1 - 3e-76 257.9 10.0 4.1e-76 257.5 10.0 1.2 1 0 0 1 1 1 1 Nuclear protein Es2 Amidohydro_1 PF01979.20 EGG12528.1 - 4.8e-10 39.3 0.0 9.5e-05 21.9 0.0 2.1 1 1 1 2 2 2 2 Amidohydrolase family Lipocalin_3 PF12702.7 EGG12528.1 - 0.039 14.0 0.4 0.11 12.5 0.4 1.8 1 0 0 1 1 1 0 Lipocalin-like WASH-7_mid PF14744.6 EGG12528.1 - 0.16 11.0 1.9 4.2 6.4 0.0 2.3 2 0 0 2 2 2 0 WASH complex subunit 7 CHZ PF09649.10 EGG12529.1 - 0.12 11.9 4.3 0.28 10.7 1.6 2.3 2 0 0 2 2 2 0 Histone chaperone domain CHZ Ribosomal_L27e PF01777.18 EGG12532.1 - 2.1e-38 130.6 1.1 2.8e-38 130.1 1.1 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EGG12532.1 - 0.0015 18.4 0.7 0.0015 18.4 0.7 1.9 2 0 0 2 2 2 1 KOW motif LIM PF00412.22 EGG12533.1 - 1.5e-15 57.2 38.9 3e-08 33.8 2.1 5.3 5 1 0 5 5 5 4 LIM domain NinD PF17466.2 EGG12533.1 - 7.6 6.7 9.1 3.3 7.9 0.3 4.0 4 0 0 4 4 4 0 Family of unknown function TRIC PF05197.13 EGG12534.1 - 0.002 17.7 0.5 0.0036 16.9 0.4 1.5 1 1 0 1 1 1 1 TRIC channel Abhydrolase_1 PF00561.20 EGG12535.1 - 8.8e-16 58.3 0.0 1.3e-14 54.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG12535.1 - 9.2e-14 52.6 0.1 2.6e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG12535.1 - 2.7e-07 30.1 0.0 5.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 CMD PF02627.20 EGG12535.1 - 3.2e-07 30.3 0.0 6.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Esterase PF00756.20 EGG12535.1 - 6.8e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.13 EGG12535.1 - 0.0025 17.5 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) TIMELESS PF04821.14 EGG12538.1 - 2e-49 168.4 6.1 3.6e-27 95.3 1.9 3.1 2 1 1 3 3 3 2 Timeless protein ERCC4 PF02732.15 EGG12539.1 - 2e-20 73.6 0.1 9e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 ERCC4 domain F-box PF00646.33 EGG12541.1 - 0.51 10.3 6.8 1 9.3 0.0 4.0 4 0 0 4 4 4 0 F-box domain PH PF00169.29 EGG12542.1 - 2.7e-09 37.5 1.2 1.5e-08 35.0 0.2 2.4 2 0 0 2 2 2 1 PH domain FCH PF00611.23 EGG12542.1 - 0.023 15.0 0.0 0.096 13.0 0.0 2.1 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Aconitase PF00330.20 EGG12545.1 - 1.6e-154 515.3 0.0 2e-154 515.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGG12545.1 - 6.9e-42 142.9 0.0 1.3e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain CHZ PF09649.10 EGG12546.1 - 8.9e-15 53.9 3.4 8.9e-15 53.9 3.4 2.1 2 0 0 2 2 2 1 Histone chaperone domain CHZ Helicase_C PF00271.31 EGG12548.1 - 7e-05 23.1 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Tetraspanin PF00335.20 EGG12549.1 - 2.4e-06 27.4 4.9 4.4e-06 26.6 4.9 1.4 1 0 0 1 1 1 1 Tetraspanin family TMEM220 PF15071.6 EGG12549.1 - 0.02 15.6 0.5 0.047 14.4 0.2 1.8 1 1 0 1 1 1 0 Transmembrane family 220, helix RhaT PF06379.12 EGG12549.1 - 0.022 14.0 1.4 0.033 13.4 1.4 1.2 1 0 0 1 1 1 0 L-rhamnose-proton symport protein (RhaT) MAS20 PF02064.15 EGG12551.1 - 8.9e-37 126.1 0.1 8.9e-37 126.1 0.1 1.8 2 0 0 2 2 2 1 MAS20 protein import receptor WH2 PF02205.20 EGG12553.1 - 4.7e-05 23.1 3.0 0.00012 21.8 0.6 2.3 2 0 0 2 2 2 1 WH2 motif Peroxin-3 PF04882.12 EGG12554.1 - 6.5 5.6 7.9 0.19 10.7 1.1 1.8 2 0 0 2 2 2 0 Peroxin-3 HSP70 PF00012.20 EGG12556.1 - 2.9 5.9 7.3 3 5.9 7.3 1.0 1 0 0 1 1 1 0 Hsp70 protein LCD1 PF09798.9 EGG12556.1 - 7 5.0 11.6 7.3 5.0 11.6 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Myb_DNA-bind_3 PF12776.7 EGG12557.1 - 1.4e-05 26.0 0.0 2.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain FA_desaturase PF00487.24 EGG12558.1 - 5e-24 85.5 24.5 2.4e-23 83.3 24.5 1.9 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EGG12558.1 - 4.4e-06 26.9 0.0 1.7e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) LON_substr_bdg PF02190.16 EGG12559.1 - 1.6e-19 70.6 1.7 2.8e-19 69.8 0.0 2.1 2 1 1 3 3 3 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EGG12559.1 - 9.4e-10 38.2 7.5 9.4e-10 38.2 7.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG12559.1 - 2.4e-07 30.5 7.8 4e-07 29.8 5.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG12559.1 - 4.6e-07 29.8 10.2 2.6e-06 27.4 4.1 3.0 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGG12559.1 - 4.6e-07 30.1 8.1 4.6e-07 30.1 8.1 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGG12559.1 - 5.7e-06 26.1 7.6 5.7e-06 26.1 7.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG12559.1 - 5.9e-06 26.1 14.6 2.4e-05 24.2 7.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGG12559.1 - 7.1e-05 22.6 6.3 7.1e-05 22.6 6.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGG12559.1 - 8.3e-05 22.7 9.1 0.00027 21.0 5.9 2.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGG12559.1 - 0.0004 20.6 2.3 0.0004 20.6 2.3 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EGG12559.1 - 0.0012 18.5 7.4 0.004 16.9 2.6 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGG12559.1 - 0.0019 18.3 5.6 0.0048 17.0 5.6 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EGG12559.1 - 0.11 12.6 0.9 0.28 11.3 0.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 EGG12559.1 - 0.13 12.0 5.5 0.49 10.1 5.5 2.0 1 0 0 1 1 1 0 P-11 zinc finger DUF1272 PF06906.11 EGG12559.1 - 0.24 11.5 4.4 0.63 10.2 4.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Tim54 PF11711.8 EGG12559.1 - 0.43 9.3 3.0 6.8 5.4 0.6 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Homeobox_KN PF05920.11 EGG12562.1 - 1.8e-17 63.0 0.4 1.8e-17 63.0 0.4 2.7 3 0 0 3 3 3 1 Homeobox KN domain Homeodomain PF00046.29 EGG12562.1 - 1.2e-05 25.0 0.2 2.8e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 Homeodomain PNGaseA PF12222.8 EGG12564.1 - 1.3e-98 330.7 0.2 3.3e-98 329.4 0.2 1.6 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A N-glycanase_N PF09112.10 EGG12564.1 - 0.064 13.1 0.0 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Peptide-N-glycosidase F, N terminal CreD PF06123.12 EGG12564.1 - 0.2 10.4 0.3 0.64 8.7 0.1 1.7 1 1 1 2 2 2 0 Inner membrane protein CreD Septin PF00735.18 EGG12565.1 - 2.1e-35 122.4 0.4 2.3e-16 59.9 0.1 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.23 EGG12565.1 - 0.0026 17.8 0.3 0.016 15.3 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGG12565.1 - 0.0048 16.3 0.1 0.01 15.2 0.1 1.5 1 0 0 1 1 1 1 AIG1 family DUF3519 PF12033.8 EGG12565.1 - 0.053 13.9 0.5 0.11 12.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) TsaE PF02367.17 EGG12565.1 - 0.055 13.5 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 EGG12565.1 - 0.11 11.9 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Spem1 PF15670.5 EGG12565.1 - 0.11 12.1 1.8 0.17 11.4 1.3 1.4 1 1 0 1 1 1 0 Spermatid maturation protein 1 Aldo_ket_red PF00248.21 EGG12566.1 - 2.4e-58 197.7 0.0 2.8e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ENTH PF01417.20 EGG12568.1 - 2.4e-46 156.8 0.3 3.6e-46 156.3 0.3 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EGG12568.1 - 0.00015 20.9 0.1 0.00025 20.2 0.1 1.3 1 0 0 1 1 1 1 ANTH domain POT1 PF02765.17 EGG12569.1 - 0.0005 19.9 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 EGG12569.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Replication protein A OB domain CDC24_OB3 PF17244.2 EGG12569.1 - 0.0073 16.0 1.2 0.0076 16.0 0.0 1.5 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 TMEM215 PF15746.5 EGG12570.1 - 0.19 11.2 0.9 0.29 10.6 0.9 1.2 1 0 0 1 1 1 0 TMEM215 family TMP_2 PF06791.13 EGG12570.1 - 2.1 8.0 16.5 3.8 7.1 16.5 1.4 1 0 0 1 1 1 0 Prophage tail length tape measure protein PLA2_B PF01735.18 EGG12571.1 - 1.4e-28 99.6 0.0 1.7e-27 96.0 0.0 2.2 1 1 0 1 1 1 1 Lysophospholipase catalytic domain E1-N PF14463.6 EGG12571.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 E1 N-terminal domain SNARE PF05739.19 EGG12572.1 - 2.8e-15 56.0 0.4 9.3e-15 54.4 0.4 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EGG12572.1 - 5.3e-05 23.0 21.3 5.3e-05 23.0 21.3 2.1 2 1 0 2 2 2 1 Syntaxin Ste5_C PF12194.8 EGG12572.1 - 0.15 12.0 6.1 0.48 10.4 0.0 2.9 2 1 1 3 3 3 0 Protein kinase Fus3-binding DUF4407 PF14362.6 EGG12572.1 - 0.57 9.5 13.8 12 5.2 13.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_8 PF00895.20 EGG12572.1 - 1.4 9.4 6.4 0.68 10.4 1.8 2.8 1 1 1 2 2 2 0 ATP synthase protein 8 GlutR_dimer PF00745.20 EGG12572.1 - 1.9 9.0 6.4 0.16 12.4 0.5 2.2 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Helicase_C PF00271.31 EGG12574.1 - 4e-08 33.6 0.1 2.4e-07 31.1 0.1 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EGG12575.1 - 1.8e-06 28.2 0.0 2.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold SRA1 PF07304.11 EGG12576.1 - 0.13 12.0 0.0 0.13 12.0 0.0 2.3 2 1 0 2 2 2 0 Steroid receptor RNA activator (SRA1) NOA36 PF06524.12 EGG12576.1 - 0.43 9.8 4.7 0.69 9.2 4.7 1.4 1 0 0 1 1 1 0 NOA36 protein Zip PF02535.22 EGG12576.1 - 0.71 9.0 4.7 0.71 9.0 4.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4692 PF15763.5 EGG12576.1 - 1.7 9.1 13.4 2.3 8.6 12.8 1.5 1 1 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) MAJIN PF15077.6 EGG12576.1 - 6 6.6 12.4 10 5.8 12.4 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein Spore_coat_CotO PF14153.6 EGG12576.1 - 6.8 6.6 15.1 9.7 6.1 15.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO adh_short PF00106.25 EGG12577.1 - 1.4e-35 122.6 0.0 1.8e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG12577.1 - 8.9e-19 68.0 0.0 1.3e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG12577.1 - 1.6e-07 31.5 0.0 2.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EGG12577.1 - 0.0045 16.6 0.0 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family CBP_BcsO PF17037.5 EGG12577.1 - 0.032 14.4 0.5 0.048 13.8 0.5 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO GDP_Man_Dehyd PF16363.5 EGG12577.1 - 0.043 13.2 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGG12577.1 - 0.061 12.4 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGG12577.1 - 0.077 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding ApbA PF02558.16 EGG12577.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EGG12577.1 - 0.16 12.6 0.1 0.5 11.0 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent WW PF00397.26 EGG12578.1 - 4.7e-05 23.4 4.2 4.7e-05 23.4 4.2 2.2 3 0 0 3 3 3 1 WW domain Retrotran_gag_2 PF14223.6 EGG12579.1 - 0.0016 18.1 0.2 0.0039 16.9 0.0 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type APG17 PF04108.12 EGG12579.1 - 0.02 14.0 1.2 0.089 11.9 0.0 2.1 2 1 0 2 2 2 0 Autophagy protein Apg17 DUF4061 PF13270.6 EGG12579.1 - 0.077 13.3 1.4 0.21 11.9 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) CxC1 PF18802.1 EGG12580.1 - 3e-30 104.4 0.1 5.4e-30 103.6 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG12580.1 - 3.8e-06 27.0 0.0 8.6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EGG12580.1 - 0.059 13.2 0.3 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases GUN4 PF05419.12 EGG12581.1 - 0.024 14.7 0.2 0.03 14.4 0.2 1.2 1 0 0 1 1 1 0 GUN4-like RNA_pol_3_Rpc31 PF11705.8 EGG12582.1 - 4 7.6 14.7 0.029 14.6 5.6 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 FAD_binding_3 PF01494.19 EGG12586.1 - 3.7e-22 79.1 0.0 9.1e-11 41.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EGG12586.1 - 2.6e-06 26.7 0.0 0.094 11.8 0.0 3.2 3 0 0 3 3 3 2 Lycopene cyclase protein SE PF08491.10 EGG12586.1 - 0.0029 16.7 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.27 EGG12586.1 - 0.012 16.2 0.1 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGG12586.1 - 0.024 13.9 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG12586.1 - 0.026 14.5 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGG12586.1 - 0.03 13.6 0.0 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGG12586.1 - 0.034 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGG12586.1 - 0.043 14.1 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EGG12586.1 - 0.048 12.5 0.0 0.54 9.0 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 EGG12586.1 - 0.16 11.2 0.1 0.32 10.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Iso_dh PF00180.20 EGG12587.1 - 2.4e-60 204.5 0.0 2.7e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GMC_oxred_N PF00732.19 EGG12590.1 - 1.5e-45 155.8 0.0 2.1e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGG12590.1 - 1.2e-34 119.9 0.0 2.4e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase HMG_box PF00505.19 EGG12592.1 - 0.075 13.5 0.0 0.23 11.9 0.0 1.8 2 0 0 2 2 2 0 HMG (high mobility group) box Chalcone_2 PF16035.5 EGG12593.1 - 5.8e-10 39.3 0.0 8.1e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like DUF1180 PF06679.12 EGG12594.1 - 8.5 6.8 16.4 1.5 9.2 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Tlr3_TMD PF17968.1 EGG12596.1 - 3.5 7.9 5.7 57 4.0 0.1 3.1 1 1 2 3 3 3 0 Toll-like receptor 3 trans-membrane domain Alba PF01918.21 EGG12597.1 - 0.00095 18.9 0.3 0.046 13.6 0.0 2.8 2 1 0 2 2 2 1 Alba TFIIE_beta PF02186.15 EGG12597.1 - 0.019 15.2 0.1 0.042 14.1 0.1 1.7 1 0 0 1 1 1 0 TFIIE beta subunit core domain DUF3605 PF12239.8 EGG12598.1 - 4.3e-15 56.4 1.5 3.3e-13 50.2 1.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) Trehalase PF01204.18 EGG12600.1 - 1.2e-19 70.5 0.4 1.3e-19 70.4 0.4 1.0 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 EGG12600.1 - 0.12 11.1 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain Retrotran_gag_2 PF14223.6 EGG12602.1 - 3.8e-08 33.1 0.1 1e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type CFEM PF05730.11 EGG12603.1 - 2.3e-10 40.4 4.4 3e-10 40.1 4.4 1.2 1 0 0 1 1 1 1 CFEM domain SNF2_N PF00176.23 EGG12605.1 - 7.9e-28 97.2 0.2 9.7e-28 96.9 0.2 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGG12605.1 - 0.0011 18.9 0.0 0.002 18.1 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGG12606.1 - 6.1e-09 36.2 0.0 9.5e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Sec1 PF00995.23 EGG12609.1 - 4e-117 392.8 0.0 4.6e-117 392.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glycos_transf_4 PF00953.21 EGG12610.1 - 1.4e-31 109.7 9.6 3.4e-31 108.4 9.6 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 4 Frtz PF11768.8 EGG12610.1 - 0.21 9.9 0.1 0.31 9.3 0.1 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Alg6_Alg8 PF03155.15 EGG12611.1 - 1e-105 354.5 26.7 1.5e-105 354.0 26.7 1.2 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family mRNA_triPase PF02940.15 EGG12612.1 - 6.2e-43 147.1 0.2 1.2e-42 146.1 0.2 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain MBOAT_2 PF13813.6 EGG12614.1 - 2.2e-12 47.1 1.5 5.7e-12 45.7 0.4 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family ERG4_ERG24 PF01222.17 EGG12616.1 - 2.3e-139 464.9 18.6 2.7e-139 464.6 18.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGG12616.1 - 4.7e-07 29.6 0.4 7.9e-07 28.8 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EGG12616.1 - 4e-05 24.0 0.7 0.0005 20.4 0.0 3.1 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 EGG12616.1 - 0.0081 16.6 0.5 0.039 14.4 0.0 2.4 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF383 PF04063.14 EGG12617.1 - 2.6e-60 203.4 0.0 5.2e-59 199.1 0.0 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EGG12617.1 - 5.4e-17 61.4 3.1 7.8e-17 60.9 2.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Cnd1 PF12717.7 EGG12617.1 - 0.018 15.1 2.0 0.31 11.1 0.1 2.9 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGG12617.1 - 0.034 14.7 0.1 4.9 7.8 0.0 3.1 3 0 0 3 3 3 0 HEAT-like repeat HEAT_2 PF13646.6 EGG12617.1 - 0.042 14.2 0.7 0.29 11.6 0.0 2.6 2 2 2 4 4 4 0 HEAT repeats HEAT PF02985.22 EGG12617.1 - 0.11 12.9 0.0 0.5 10.8 0.0 2.2 1 0 0 1 1 1 0 HEAT repeat Ceramidase_alk PF04734.13 EGG12618.1 - 3.7e-197 656.0 0.0 4.4e-197 655.7 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EGG12618.1 - 2.4e-46 157.7 0.1 3.7e-46 157.1 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal SKICH PF17751.1 EGG12618.1 - 0.013 16.1 0.2 0.03 14.9 0.2 1.6 1 0 0 1 1 1 0 SKICH domain Thiamine_BP PF01910.17 EGG12619.1 - 1.7e-31 108.0 0.0 2e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Ykof PF07615.11 EGG12619.1 - 0.045 14.2 0.0 0.07 13.6 0.0 1.3 1 0 0 1 1 1 0 YKOF-related Family STN PF07660.14 EGG12619.1 - 0.2 11.5 0.0 0.46 10.3 0.0 1.7 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain Solute_trans_a PF03619.16 EGG12620.1 - 1.6e-82 277.0 25.4 1.9e-82 276.8 25.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DAO PF01266.24 EGG12621.1 - 3.2e-27 96.1 0.0 4.2e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG12621.1 - 3.6e-08 33.0 1.3 0.00037 19.8 0.2 1.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGG12621.1 - 9.4e-06 25.2 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGG12621.1 - 1.8e-05 24.1 0.8 2.6e-05 23.5 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EGG12621.1 - 0.0047 16.2 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGG12621.1 - 0.0049 15.6 2.3 0.0091 14.7 0.3 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EGG12621.1 - 0.0056 15.8 0.1 0.0076 15.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGG12621.1 - 0.0064 16.7 0.5 0.012 15.8 0.5 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGG12621.1 - 0.0096 16.5 0.2 0.021 15.4 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EGG12621.1 - 0.018 14.9 1.7 0.024 14.5 0.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3255 PF11631.8 EGG12621.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) Methyltransf_34 PF11312.8 EGG12621.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase DUF3412 PF11892.8 EGG12621.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) DnaJ PF00226.31 EGG12623.1 - 8.5e-16 57.8 0.6 1.6e-15 56.9 0.2 1.6 2 0 0 2 2 2 1 DnaJ domain zf-CSL PF05207.13 EGG12623.1 - 3.5e-15 55.5 0.8 7.5e-15 54.4 0.8 1.6 1 0 0 1 1 1 1 CSL zinc finger Lum_binding PF00677.17 EGG12623.1 - 0.022 14.7 0.3 0.059 13.4 0.2 1.7 2 1 0 2 2 2 0 Lumazine binding domain Alpha_E3_glycop PF01563.16 EGG12623.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein Retrotran_gag_2 PF14223.6 EGG12625.1 - 8.2e-07 28.8 0.6 1.2e-06 28.3 0.6 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGG12625.1 - 0.093 12.6 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF2462 PF09495.10 EGG12626.1 - 1.8e-14 54.2 4.7 1.8e-14 54.2 4.7 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Cytomega_UL20A PF05984.12 EGG12627.1 - 0.019 15.3 1.0 0.027 14.8 1.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Menin PF05053.13 EGG12627.1 - 0.082 11.3 0.6 0.1 11.0 0.6 1.1 1 0 0 1 1 1 0 Menin CoatB PF10389.9 EGG12627.1 - 1.6 8.7 0.0 1.6 8.7 0.0 2.7 3 0 0 3 3 3 0 Bacteriophage coat protein B MRNIP PF15749.5 EGG12629.1 - 0.0002 22.0 2.2 0.00026 21.7 2.2 1.1 1 0 0 1 1 1 1 MRN-interacting protein Ndufs5 PF10200.9 EGG12629.1 - 0.012 15.8 3.6 0.022 15.0 3.6 1.5 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.13 EGG12629.1 - 0.058 13.6 6.1 2.2 8.5 0.1 2.4 1 1 1 2 2 2 0 CHCH domain COX17 PF05051.13 EGG12629.1 - 0.088 13.2 0.8 0.78 10.1 1.0 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.8 EGG12629.1 - 0.1 13.0 9.9 0.53 10.7 9.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) PADR1 PF08063.12 EGG12629.1 - 0.16 11.7 1.9 1 9.2 0.3 2.1 1 1 1 2 2 2 0 PADR1 (NUC008) domain DUF1690 PF07956.11 EGG12629.1 - 0.27 11.6 10.3 1.5 9.2 0.2 2.1 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Cmc1 PF08583.10 EGG12629.1 - 0.33 11.0 5.1 0.75 9.9 5.1 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 EGG12629.1 - 0.64 10.3 8.9 6 7.2 9.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) UCH PF00443.29 EGG12630.1 - 6.8e-49 166.7 0.0 8.6e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG12630.1 - 4.4e-08 33.1 0.2 0.005 16.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 EGG12631.1 - 2.8e-18 65.9 4.5 1.9e-08 34.8 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG12631.1 - 7.3e-06 26.2 0.2 0.0003 21.0 0.1 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Formyl_trans_C PF02911.18 EGG12631.1 - 0.042 14.1 0.1 0.28 11.4 0.0 2.4 3 0 0 3 3 3 0 Formyl transferase, C-terminal domain PQQ_3 PF13570.6 EGG12631.1 - 0.044 14.3 0.2 49 4.6 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain WD40_like PF17005.5 EGG12631.1 - 0.15 11.4 0.1 5 6.3 0.1 2.4 1 1 0 1 1 1 0 WD40-like domain BBS2_Mid PF14783.6 EGG12631.1 - 0.23 11.5 0.7 4.4 7.4 0.1 3.1 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region SARAF PF06682.12 EGG12632.1 - 1.5e-57 195.7 10.9 2.2e-55 188.7 10.9 2.8 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CM_2 PF01817.21 EGG12633.1 - 6.2e-05 23.3 0.0 8.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Chorismate mutase type II Yip1 PF04893.17 EGG12635.1 - 8.5e-19 67.9 23.2 1.2e-18 67.4 23.2 1.2 1 0 0 1 1 1 1 Yip1 domain SH3_9 PF14604.6 EGG12636.1 - 4.2e-18 64.9 0.4 4e-10 39.4 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 EGG12636.1 - 2.2e-17 63.1 0.3 1.4e-16 60.5 0.1 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 EGG12636.1 - 2.9e-12 46.3 4.2 4.7e-12 45.6 4.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 EGG12636.1 - 1.8e-11 43.4 0.1 4e-06 26.3 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGG12636.1 - 3.8e-11 42.5 0.1 3.7e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 EGG12636.1 - 9.2e-06 25.8 1.3 0.059 13.7 0.3 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain PHD PF00628.29 EGG12636.1 - 0.34 10.9 3.0 0.65 9.9 3.0 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 EGG12636.1 - 2.1 8.7 5.1 4.3 7.7 5.1 1.5 1 0 0 1 1 1 0 RING-like domain Vps5 PF09325.10 EGG12637.1 - 0.03 13.9 2.7 0.05 13.1 2.6 1.5 2 0 0 2 2 2 0 Vps5 C terminal like DUF3774 PF12609.8 EGG12637.1 - 1 10.4 5.4 0.38 11.8 0.8 2.1 1 1 1 2 2 2 0 Wound-induced protein PSI_PsaE PF02427.17 EGG12638.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IV / PsaE Mad3_BUB1_I PF08311.12 EGG12640.1 - 1.6e-24 86.3 1.1 3.8e-24 85.0 1.1 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 EGG12640.1 - 1.5e-14 54.0 0.0 2.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG12640.1 - 7e-06 25.5 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.11 EGG12640.1 - 0.14 12.3 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 Cellulase PF00150.18 EGG12641.1 - 5.3e-09 35.9 2.7 1.1e-07 31.6 2.7 2.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF641 PF04859.12 EGG12642.1 - 0.0064 16.8 7.1 0.022 15.1 0.2 2.5 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) Stealth_CR1 PF17101.5 EGG12642.1 - 0.21 11.3 0.0 0.52 10.1 0.0 1.7 1 0 0 1 1 1 0 Stealth protein CR1, conserved region 1 VPS38 PF17649.1 EGG12642.1 - 0.41 9.5 6.2 0.11 11.4 3.1 1.5 1 1 1 2 2 2 0 Vacuolar protein sorting 38 DUF5542 PF17696.1 EGG12642.1 - 0.41 10.8 2.5 2.2 8.4 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5542) Cnn_1N PF07989.11 EGG12642.1 - 0.47 10.6 5.5 2 8.6 0.5 2.9 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 KLRAQ PF10205.9 EGG12642.1 - 0.51 10.6 8.7 0.52 10.6 0.1 3.8 3 1 1 4 4 4 0 Predicted coiled-coil domain-containing protein ADIP PF11559.8 EGG12642.1 - 1.4 9.0 17.1 3.5 7.7 4.6 2.5 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cdh1_DBD_1 PF18196.1 EGG12642.1 - 3.5 8.0 8.0 0.47 10.8 0.8 2.2 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Sec2p PF06428.11 EGG12642.1 - 9.6 6.3 10.4 1.7 8.7 2.9 2.7 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Transp_cyt_pur PF02133.15 EGG12643.1 - 7.6e-126 420.4 41.0 1.7e-125 419.3 41.0 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SAYSvFN PF10260.9 EGG12643.1 - 0.81 9.7 5.5 0.25 11.3 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) DUF4218 PF13960.6 EGG12644.1 - 0.00021 20.9 0.3 0.00059 19.4 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) KDZ PF18758.1 EGG12645.1 - 1.9e-58 197.7 0.2 3.5e-58 196.8 0.2 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGG12645.1 - 1.2e-28 99.3 0.1 4e-28 97.6 0.1 2.0 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG12645.1 - 0.07 13.3 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases EST1 PF10374.9 EGG12645.1 - 0.086 13.5 3.9 0.43 11.2 0.2 2.7 2 0 0 2 2 2 0 Telomerase activating protein Est1 SSFA2_C PF14723.6 EGG12645.1 - 0.14 12.1 2.9 0.1 12.5 0.7 1.9 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Gemini_C4 PF01492.17 EGG12646.1 - 0.0062 16.4 1.1 0.016 15.1 1.1 1.6 1 0 0 1 1 1 1 Geminivirus C4 protein DNA_primase_lrg PF04104.14 EGG12647.1 - 2.3e-16 60.0 0.0 3.9e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit HlyE PF06109.13 EGG12647.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Haemolysin E (HlyE) DNA_primase_lrg PF04104.14 EGG12648.1 - 7.3e-18 64.9 0.3 8.3e-18 64.7 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF3373 PF11853.8 EGG12649.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) TFCD_C PF12612.8 EGG12651.1 - 1.4e-18 67.4 0.7 2.2e-17 63.5 0.0 3.1 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EGG12651.1 - 0.00036 20.5 5.9 0.64 10.4 0.0 6.3 8 0 0 8 8 8 1 HEAT repeat HEAT_2 PF13646.6 EGG12651.1 - 0.0018 18.6 0.4 2.9 8.3 0.0 5.1 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 EGG12651.1 - 0.0064 17.0 0.6 2.4 8.8 0.0 4.1 3 1 0 3 3 3 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGG12651.1 - 0.01 16.4 0.1 0.4 11.3 0.0 3.3 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EGG12651.1 - 0.042 14.0 0.0 0.36 11.0 0.0 2.4 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4381 PF14316.6 EGG12651.1 - 0.074 13.3 0.0 0.3 11.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Cnd1 PF12717.7 EGG12651.1 - 0.099 12.7 0.1 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Gly_transf_sug PF04488.15 EGG12653.1 - 1e-10 42.1 0.1 1.7e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Complex1_49kDa PF00346.19 EGG12653.1 - 0.035 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit GCIP PF13324.6 EGG12654.1 - 0.0019 17.9 0.0 0.0029 17.3 0.0 1.3 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting SOG2 PF10428.9 EGG12655.1 - 0.22 10.7 13.4 0.27 10.4 13.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Hydin_ADK PF17213.3 EGG12655.1 - 9 6.5 11.0 8.8 6.5 8.0 2.0 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain Ribosomal_L10 PF00466.20 EGG12657.1 - 6.5e-24 84.0 0.7 4.6e-23 81.2 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EGG12657.1 - 5.8e-21 74.3 0.1 1e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EGG12657.1 - 3.5e-17 62.8 8.4 4e-17 62.6 6.1 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Glyoxalase PF00903.25 EGG12658.1 - 2.3e-18 66.6 0.1 3.1e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGG12658.1 - 3.4e-07 30.5 0.1 6.5e-07 29.6 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EGG12658.1 - 0.00012 22.8 0.0 0.00017 22.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EGG12658.1 - 0.0022 17.9 0.1 0.0082 16.1 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EGG12658.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.5 2 0 0 2 2 2 0 Glyoxalase-like domain CppA_N PF14506.6 EGG12658.1 - 0.089 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal YchF-GTPase_C PF06071.13 EGG12659.1 - 8.6e-36 122.0 0.3 2.7e-35 120.4 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGG12659.1 - 4.4e-18 65.4 0.0 1.3e-17 63.9 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG12659.1 - 5.8e-06 25.9 0.0 1.6e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B BetaGal_dom3 PF13363.6 EGG12659.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 Hydrolase_4 PF12146.8 EGG12660.1 - 0.00023 20.5 0.1 0.6 9.3 0.0 2.8 1 1 2 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG12660.1 - 0.025 14.2 3.0 2.6 7.6 0.1 2.9 2 1 1 3 3 3 0 alpha/beta hydrolase fold NTP_transf_9 PF04248.12 EGG12661.1 - 7.3e-27 93.1 0.5 8.5e-27 92.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) adh_short_C2 PF13561.6 EGG12662.1 - 4.9e-50 170.3 0.0 6e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG12662.1 - 8.3e-36 123.3 0.1 1e-35 123.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG12662.1 - 5.1e-11 42.8 0.0 7.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGG12662.1 - 0.005 16.0 0.0 0.007 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SPC25 PF06703.11 EGG12663.1 - 7.9e-41 139.5 1.6 9.8e-41 139.2 1.6 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Gly_transf_sug PF04488.15 EGG12664.1 - 1.1e-05 26.0 0.1 6.2e-05 23.6 0.0 2.3 3 0 0 3 3 3 1 Glycosyltransferase sugar-binding region containing DXD motif FAM60A PF15396.6 EGG12664.1 - 0.18 11.8 4.6 1.6 8.7 0.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Caps_synth PF05704.12 EGG12664.1 - 0.84 9.0 3.2 0.24 10.8 0.2 1.6 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein LapA_dom PF06305.11 EGG12665.1 - 0.047 13.5 0.4 0.1 12.5 0.4 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF1772 PF08592.11 EGG12665.1 - 1.1 9.6 5.9 0.38 11.1 1.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Tcp11 PF05794.13 EGG12667.1 - 5.4e-102 342.1 0.0 9.3e-102 341.4 0.0 1.4 1 0 0 1 1 1 1 T-complex protein 11 GalP_UDP_transf PF01087.22 EGG12670.1 - 9.9e-60 202.1 0.1 1.4e-59 201.6 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EGG12670.1 - 1.9e-45 154.6 0.0 4.2e-45 153.5 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 EGG12670.1 - 0.013 14.3 0.4 0.84 8.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) DIE2_ALG10 PF04922.12 EGG12671.1 - 1e-121 407.0 15.5 1.2e-121 406.7 15.5 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family PBD PF00786.28 EGG12674.1 - 0.24 11.8 1.1 0.45 10.9 0.0 2.0 2 0 0 2 2 2 0 P21-Rho-binding domain Tantalus PF15386.6 EGG12674.1 - 1.8 8.7 5.7 0.51 10.5 0.3 2.5 2 0 0 2 2 2 0 Drosophila Tantalus-like LNP1 PF15419.6 EGG12677.1 - 0.01 16.1 1.0 0.03 14.6 0.4 2.0 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 4HBT PF03061.22 EGG12678.1 - 1.9e-11 44.1 0.0 3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily HD_3 PF13023.6 EGG12679.1 - 8.2e-46 155.9 0.1 1e-45 155.6 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EGG12679.1 - 6.7e-12 45.5 0.1 1e-11 44.9 0.1 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EGG12679.1 - 9.7e-06 25.8 0.3 6.1e-05 23.2 0.3 2.0 1 1 0 1 1 1 1 HD domain DUF4765 PF15962.5 EGG12679.1 - 0.059 11.3 0.0 0.074 11.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4765) Pectinesterase PF01095.19 EGG12680.1 - 6.2e-38 130.2 1.5 9.2e-38 129.6 1.5 1.1 1 0 0 1 1 1 1 Pectinesterase PGM_PMM_II PF02879.16 EGG12681.1 - 0.063 13.9 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Phosphodiest PF01663.22 EGG12682.1 - 3.4e-76 257.1 1.3 4.3e-76 256.8 1.3 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGG12682.1 - 0.018 14.5 0.1 0.94 8.8 0.0 2.3 2 0 0 2 2 2 0 Sulfatase DUF3568 PF12092.8 EGG12683.1 - 0.22 11.6 2.5 0.43 10.7 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) SWIRM-assoc_2 PF16496.5 EGG12683.1 - 0.64 8.8 3.3 1.4 7.7 3.3 1.5 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Ldl_recept_a PF00057.18 EGG12684.1 - 0.88 9.8 6.7 0.38 11.0 4.2 1.6 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A ADK PF00406.22 EGG12685.1 - 6.4e-43 146.4 0.0 2.2e-42 144.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 EGG12685.1 - 2.3e-19 70.2 0.0 4.8e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EGG12685.1 - 1.2e-14 54.0 0.0 2.8e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EGG12685.1 - 0.00018 22.0 0.0 0.00043 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG12685.1 - 0.032 14.4 0.0 0.21 11.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGG12685.1 - 0.064 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2572 PF10833.8 EGG12686.1 - 1.6 8.5 7.5 2.3 7.9 7.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2572) Anemone_cytotox PF06369.12 EGG12687.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Sea anemone cytotoxic protein OPA3 PF07047.12 EGG12688.1 - 1.4e-42 144.4 0.2 2e-42 143.9 0.2 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Mod_r PF07200.13 EGG12688.1 - 0.0056 16.8 1.0 0.011 15.9 1.0 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein HLH PF00010.26 EGG12688.1 - 0.052 13.5 0.1 0.096 12.7 0.1 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Cellulase PF00150.18 EGG12689.1 - 2.7e-12 46.7 0.0 1.2e-07 31.5 0.0 2.9 3 0 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EGG12689.1 - 7.4e-10 39.2 0.3 5.5e-09 36.4 0.1 2.2 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 EGG12689.1 - 0.024 14.3 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Glyco_hydro_14 PF01373.17 EGG12689.1 - 0.029 13.3 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 Histone PF00125.24 EGG12690.1 - 1.5e-51 174.2 2.6 1.6e-51 174.1 2.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGG12690.1 - 0.00014 22.5 1.2 0.00016 22.2 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EGG12690.1 - 0.00015 22.1 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGG12690.1 - 0.00019 21.5 0.5 0.00028 20.9 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EGG12690.1 - 0.002 18.4 0.1 0.0038 17.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGG12690.1 - 0.034 14.2 0.2 0.055 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PRAI PF00697.22 EGG12690.1 - 0.15 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Methyltransf_PK PF05891.12 EGG12691.1 - 2.5e-51 174.3 0.0 2.8e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EGG12691.1 - 2.6e-08 34.5 0.0 3.8e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG12691.1 - 2.7e-05 24.7 0.0 4.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG12691.1 - 0.00015 22.5 0.0 0.00021 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG12691.1 - 0.0022 17.9 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG12691.1 - 0.18 11.3 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain WD40 PF00400.32 EGG12693.1 - 1.1e-10 41.9 5.9 0.0009 20.0 0.0 5.2 7 0 0 7 7 7 2 WD domain, G-beta repeat F-box PF00646.33 EGG12693.1 - 1.1e-07 31.5 2.5 2.7e-07 30.3 0.4 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGG12693.1 - 6.2e-06 26.0 0.3 1.2e-05 25.1 0.3 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 EGG12693.1 - 0.0014 17.4 0.0 0.0032 16.2 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EGG12693.1 - 0.0023 18.4 2.1 2.3 8.8 0.0 4.4 6 0 0 6 6 6 1 PQQ-like domain CCDC92 PF14916.6 EGG12693.1 - 0.039 13.7 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function CCCAP PF15964.5 EGG12693.1 - 0.12 10.6 0.0 0.21 9.8 0.0 1.3 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family eIF3_N PF09440.10 EGG12694.1 - 4.8e-45 153.3 2.1 9.5e-45 152.3 2.1 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EGG12694.1 - 2.2e-09 37.7 0.0 8.4e-09 35.9 0.0 2.0 1 0 0 1 1 1 1 PCI domain CCDC92 PF14916.6 EGG12694.1 - 0.09 12.6 0.5 13 5.6 0.0 3.0 2 0 0 2 2 2 0 Coiled-coil domain of unknown function CelTOS PF18659.1 EGG12694.1 - 0.11 13.0 0.2 0.26 11.7 0.2 1.6 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites CENP-T_C PF15511.6 EGG12695.1 - 4.8e-08 33.1 0.1 5.9e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EGG12695.1 - 8.4e-05 22.7 0.1 0.00012 22.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGG12695.1 - 0.00018 21.9 0.0 0.00023 21.5 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EGG12695.1 - 0.0011 19.4 0.1 0.0012 19.2 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGG12695.1 - 0.0015 18.7 0.1 0.0029 17.8 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGG12695.1 - 0.073 13.2 0.0 0.082 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_L27A PF00828.19 EGG12695.1 - 0.45 11.2 4.0 0.57 10.9 4.0 1.3 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF455 PF04305.14 EGG12697.1 - 1.3e-89 300.0 0.0 1.3e-89 300.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF455) Rieske PF00355.26 EGG12697.1 - 2.3e-05 24.2 0.0 4.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EGG12697.1 - 0.032 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain DUF2370 PF10176.9 EGG12697.1 - 1.5 8.4 6.2 0.98 9.0 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) MFS_2 PF13347.6 EGG12698.1 - 0.23 10.0 0.0 0.31 9.5 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Gemini_mov PF01708.16 EGG12699.1 - 0.24 11.2 0.3 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Geminivirus putative movement protein LEA_2 PF03168.13 EGG12700.1 - 0.00012 22.6 0.0 0.00021 21.8 0.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein Mito_carr PF00153.27 EGG12701.1 - 1.6e-51 172.2 2.4 8.1e-18 64.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ost5 PF05251.12 EGG12701.1 - 0.017 15.3 1.3 0.13 12.6 0.1 2.8 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 cwf18 PF08315.12 EGG12702.1 - 2.6e-25 89.6 0.7 3e-25 89.4 0.7 1.0 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Med9 PF07544.13 EGG12702.1 - 0.024 14.7 0.4 0.032 14.3 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DEAD PF00270.29 EGG12703.1 - 1.4e-33 116.1 0.0 7.1e-33 113.8 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG12703.1 - 1.6e-24 86.4 0.2 4.6e-22 78.5 0.1 2.9 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGG12703.1 - 2.6e-09 37.3 1.0 1.6e-08 34.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CxC5 PF18718.1 EGG12705.1 - 6e-30 103.7 6.6 1.1e-29 102.9 6.6 1.5 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EGG12705.1 - 2.2e-19 69.5 1.6 7.5e-19 67.8 0.6 2.4 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases DUF4988 PF16378.5 EGG12707.1 - 0.00042 20.0 1.9 0.0047 16.6 0.2 2.9 2 1 1 3 3 3 1 Domain of unknown function FliJ PF02050.16 EGG12707.1 - 0.0029 17.8 0.8 0.0029 17.8 0.8 1.9 2 0 0 2 2 2 1 Flagellar FliJ protein Baculo_PEP_C PF04513.12 EGG12707.1 - 0.05 13.6 4.5 0.066 13.3 3.5 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus VasL PF12486.8 EGG12707.1 - 0.053 13.4 2.9 0.085 12.7 2.5 1.5 1 1 0 1 1 1 0 Type VI secretion system, EvfB, or VasL Fib_alpha PF08702.10 EGG12707.1 - 0.054 13.7 3.5 0.075 13.2 2.2 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family SH3BP5 PF05276.14 EGG12707.1 - 0.071 12.9 5.8 0.11 12.3 5.8 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Lipoprotein_6 PF01441.19 EGG12707.1 - 0.095 12.7 4.6 0.11 12.5 3.2 1.7 1 1 1 2 2 2 0 Lipoprotein DUF3209 PF11483.8 EGG12707.1 - 0.13 12.7 1.5 0.29 11.6 1.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3209) Fzo_mitofusin PF04799.13 EGG12707.1 - 0.16 11.5 4.2 0.14 11.7 2.3 1.8 1 1 1 2 2 2 0 fzo-like conserved region Spc7 PF08317.11 EGG12707.1 - 0.21 10.4 11.0 0.47 9.3 11.0 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein CdvA PF18822.1 EGG12707.1 - 0.22 11.3 9.8 0.3 10.9 2.9 2.7 1 1 1 2 2 2 0 CdvA-like coiled-coil domain BLOC1_2 PF10046.9 EGG12707.1 - 0.23 11.8 6.6 0.24 11.7 4.5 2.1 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YojJ PF10372.9 EGG12707.1 - 0.3 11.2 3.5 8.1 6.6 0.2 2.6 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus FlaC_arch PF05377.11 EGG12707.1 - 0.36 11.3 5.5 6.8 7.2 1.1 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) BRE1 PF08647.11 EGG12707.1 - 0.49 10.5 14.7 8 6.6 6.0 3.0 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 EGG12707.1 - 0.49 10.5 12.2 0.26 11.4 10.0 1.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 EGG12707.1 - 0.54 10.3 3.8 0.79 9.8 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4600 PF15372.6 EGG12707.1 - 1.3 9.5 6.9 4.7 7.6 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Phage_GP20 PF06810.11 EGG12707.1 - 1.6 8.5 11.0 0.82 9.5 7.7 2.0 1 1 0 2 2 2 0 Phage minor structural protein GP20 Cep57_CLD_2 PF14197.6 EGG12707.1 - 2.1 8.5 9.1 0.62 10.2 0.2 3.2 2 1 0 3 3 3 0 Centrosome localisation domain of PPC89 Prefoldin_2 PF01920.20 EGG12707.1 - 2.7 8.0 11.9 4.3 7.3 8.1 2.7 1 1 0 1 1 1 0 Prefoldin subunit FapA PF03961.13 EGG12707.1 - 6.1 5.3 8.9 24 3.4 8.9 1.8 1 1 0 1 1 1 0 Flagellar Assembly Protein A CENP-F_leu_zip PF10473.9 EGG12707.1 - 9 6.3 16.9 5.6 7.0 12.3 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tmemb_cc2 PF10267.9 EGG12708.1 - 6.9 5.7 8.1 11 5.0 8.1 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein GAS PF13851.6 EGG12709.1 - 0.051 12.9 0.3 0.075 12.4 0.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SHE3 PF17078.5 EGG12709.1 - 0.06 13.0 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 CDP-OH_P_transf PF01066.21 EGG12711.1 - 1.6e-12 48.0 0.3 1.6e-12 48.0 0.3 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF2721 PF11026.8 EGG12711.1 - 0.0014 18.6 0.3 0.046 13.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2721) Defensin_2 PF01097.18 EGG12718.1 - 1e-17 63.7 41.7 0.058 13.3 0.1 15.6 16 0 0 16 16 16 8 Arthropod defensin Mago-bind PF09282.10 EGG12718.1 - 8.8e-05 22.3 8.9 96 3.0 0.0 9.3 10 0 0 10 10 10 0 Mago binding LPD15 PF18828.1 EGG12718.1 - 0.39 10.6 0.8 1.2e+02 2.7 0.0 4.0 5 0 0 5 5 5 0 Large polyvalent-protein-associated domain 15 DDDD PF10161.9 EGG12719.1 - 0.29 10.9 1.7 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Putative mitochondrial precursor protein DUF1290 PF06947.12 EGG12719.1 - 0.31 11.1 5.2 1 9.5 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1290) DUF1294 PF06961.13 EGG12720.1 - 0.097 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) Barwin PF00967.17 EGG12721.1 - 0.0012 18.7 0.1 0.0025 17.6 0.1 1.7 1 0 0 1 1 1 1 Barwin family Pollen_allerg_1 PF01357.21 EGG12721.1 - 0.0021 18.1 2.2 0.004 17.2 0.7 2.1 2 0 0 2 2 2 1 Pollen allergen Keratin_matx PF04579.12 EGG12721.1 - 0.024 15.0 0.1 0.043 14.1 0.1 1.6 1 0 0 1 1 1 0 Keratin, high-sulphur matrix protein Mo-co_dimer PF03404.16 EGG12721.1 - 0.043 13.8 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Mo-co oxidoreductase dimerisation domain BNR PF02012.20 EGG12721.1 - 0.19 11.9 0.5 0.19 11.9 0.5 2.7 3 0 0 3 3 3 0 BNR/Asp-box repeat DUF2207 PF09972.9 EGG12722.1 - 0.062 12.1 0.0 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MLANA PF14991.6 EGG12722.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A Ilar_coat PF01787.16 EGG12722.1 - 4 7.2 7.2 5.1 6.9 6.2 1.7 1 1 0 1 1 1 0 Ilarvirus coat protein PRP21_like_P PF12230.8 EGG12723.1 - 4.1e-44 151.0 21.3 4.1e-44 151.0 21.3 2.8 3 0 0 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EGG12723.1 - 1.4e-30 105.0 7.8 4.7e-15 55.3 0.2 2.8 3 0 0 3 3 3 2 Surp module ubiquitin PF00240.23 EGG12723.1 - 2.1e-07 30.6 0.0 5.8e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family SUIM_assoc PF16619.5 EGG12723.1 - 0.00013 22.0 0.0 0.19 11.8 0.0 3.3 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 zf_UBZ PF18439.1 EGG12723.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Gly_radical PF01228.21 EGG12723.1 - 0.13 12.8 1.0 0.41 11.2 0.5 2.2 2 0 0 2 2 2 0 Glycine radical Aldo_ket_red PF00248.21 EGG12724.1 - 4.1e-46 157.5 0.0 4.4e-45 154.1 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Elongin_A PF06881.11 EGG12725.1 - 2.6e-30 105.1 0.0 4.2e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A STAT_alpha PF01017.20 EGG12726.1 - 0.0051 16.7 4.2 0.0087 16.0 4.2 1.5 1 1 0 1 1 1 1 STAT protein, all-alpha domain DUF2935 PF11155.8 EGG12726.1 - 0.0082 16.5 1.1 0.0082 16.5 1.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF2935) AI-2E_transport PF01594.16 EGG12726.1 - 0.018 14.2 4.3 0.026 13.7 4.1 1.3 1 1 0 1 1 1 0 AI-2E family transporter Occludin_ELL PF07303.13 EGG12726.1 - 0.049 14.4 0.2 0.087 13.6 0.2 1.5 1 0 0 1 1 1 0 Occludin homology domain BLOC1_2 PF10046.9 EGG12726.1 - 0.25 11.7 4.4 0.54 10.6 4.2 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Herpes_LMP1 PF05297.11 EGG12727.1 - 0.081 12.1 6.8 0.08 12.1 6.8 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Col_cuticle_N PF01484.17 EGG12727.1 - 0.1 12.7 1.0 0.1 12.7 1.0 2.2 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain DUF2157 PF09925.9 EGG12727.1 - 0.11 12.2 4.3 0.12 12.1 4.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Ac76 PF05814.11 EGG12727.1 - 0.86 9.7 7.7 1 9.4 7.7 1.1 1 0 0 1 1 1 0 Orf76 (Ac76) DUF4131 PF13567.6 EGG12727.1 - 2.4 7.8 7.4 2.6 7.7 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) EMP24_GP25L PF01105.24 EGG12729.1 - 1.1e-45 155.8 0.0 1.2e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PHP PF02811.19 EGG12730.1 - 2.2e-12 47.6 0.9 3.9e-12 46.8 0.9 1.4 1 1 0 1 1 1 1 PHP domain polyprenyl_synt PF00348.17 EGG12732.1 - 3.1e-48 164.1 0.0 4.1e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase CMS1 PF14617.6 EGG12736.1 - 1.2e-41 142.7 0.1 4e-40 137.8 0.0 2.1 1 1 1 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Lin-8 PF03353.15 EGG12736.1 - 0.86 9.1 7.0 1.2 8.7 7.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NST1 PF13945.6 EGG12736.1 - 1.1 9.4 9.3 1.5 8.9 9.3 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator GCV_H PF01597.19 EGG12737.1 - 1.9e-40 137.5 0.4 2.3e-40 137.3 0.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EGG12737.1 - 0.0031 17.3 0.6 0.0072 16.1 0.4 1.7 1 1 1 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.6 EGG12737.1 - 0.0075 16.2 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 EGG12737.1 - 0.028 13.6 0.1 0.8 8.9 0.1 2.1 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GP70 PF17429.2 EGG12737.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Gene product 70 Ig_mannosidase PF17753.1 EGG12738.1 - 4.6e-17 61.5 0.1 1.3e-16 60.1 0.1 1.8 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 EGG12738.1 - 1.6e-14 54.3 0.0 5.3e-14 52.6 0.0 2.0 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_C PF02836.17 EGG12738.1 - 0.011 14.9 0.0 0.042 13.0 0.0 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 EGG12738.1 - 0.015 16.0 0.0 0.059 14.0 0.0 2.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 DUF4158 PF13700.6 EGG12739.1 - 0.0085 15.9 1.0 0.27 11.0 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4158) COesterase PF00135.28 EGG12740.1 - 5.4e-72 243.3 0.0 1.1e-71 242.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EGG12740.1 - 1.4e-07 31.2 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGG12740.1 - 1.5e-06 28.2 0.0 1.3e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 EGG12740.1 - 0.0047 16.6 0.0 0.0095 15.6 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Say1_Mug180 PF10340.9 EGG12740.1 - 0.13 11.1 0.0 0.33 9.8 0.0 1.6 2 0 0 2 2 2 0 Steryl acetyl hydrolase DNA_repr_REX1B PF14966.6 EGG12741.1 - 6.1e-06 26.8 3.6 0.0027 18.3 0.2 2.8 2 1 1 3 3 3 2 DNA repair REX1-B LMSTEN PF07988.12 EGG12741.1 - 3.9 7.0 7.1 1.2 8.6 0.7 2.6 3 0 0 3 3 3 0 LMSTEN motif RVT_3 PF13456.6 EGG12743.1 - 1.8e-06 27.8 0.0 3.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like NPR2 PF06218.11 EGG12747.1 - 6.8e-82 275.6 0.0 5.4e-66 223.2 0.0 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 GDP_Man_Dehyd PF16363.5 EGG12748.1 - 1.9e-55 188.6 0.0 2.2e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG12748.1 - 1.1e-43 149.5 0.0 1.3e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGG12748.1 - 1.2e-09 37.8 0.0 1.2e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EGG12748.1 - 1.7e-08 33.8 0.0 2.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGG12748.1 - 1.3e-07 31.0 0.0 2.6e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGG12748.1 - 0.013 14.7 0.0 5.5 6.0 0.0 2.8 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein HEAT_EZ PF13513.6 EGG12748.1 - 0.096 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 HEAT-like repeat KR PF08659.10 EGG12748.1 - 0.15 12.0 0.4 8.5 6.2 0.1 2.8 2 1 1 3 3 3 0 KR domain adh_short PF00106.25 EGG12748.1 - 0.16 11.4 0.0 0.84 9.1 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase VirE PF05272.11 EGG12749.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E SKI PF01202.22 EGG12749.1 - 0.047 13.8 0.1 0.082 13.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate kinase Ibs_toxin PF13956.6 EGG12749.1 - 2.3 8.3 5.5 1.4 9.0 3.3 1.8 1 1 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system SRPRB PF09439.10 EGG12751.1 - 1.8e-09 37.3 0.5 4e-08 32.9 0.5 2.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGG12751.1 - 6.6e-05 22.5 0.1 0.00015 21.4 0.1 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 EGG12751.1 - 0.0031 17.5 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EGG12751.1 - 0.078 13.0 0.0 0.63 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGG12751.1 - 0.097 12.9 0.0 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Phytochelatin PF05023.14 EGG12752.1 - 0.089 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Phytochelatin synthase Pro_dh PF01619.18 EGG12753.1 - 2.8e-54 184.6 0.0 1.8e-53 182.0 0.0 1.9 1 1 0 1 1 1 1 Proline dehydrogenase Macoilin PF09726.9 EGG12754.1 - 2.1 6.8 18.9 3.3 6.2 18.9 1.4 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 EGG12754.1 - 6.5 4.8 24.8 9.1 4.3 24.8 1.2 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 EGG12754.1 - 8.3 5.4 18.9 3.2 6.7 16.7 1.4 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) TPT PF03151.16 EGG12755.1 - 3e-23 82.6 18.0 4e-23 82.2 18.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGG12755.1 - 1.1e-08 35.3 28.0 4.6e-05 23.6 6.1 2.5 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EGG12755.1 - 0.005 16.1 18.5 0.0072 15.6 18.5 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport NPCC PF08058.11 EGG12755.1 - 0.03 14.4 0.1 0.078 13.0 0.1 1.7 1 0 0 1 1 1 0 Nuclear pore complex component Glycophorin_A PF01102.18 EGG12755.1 - 1.3 9.2 5.4 0.91 9.8 1.6 2.6 2 1 0 2 2 2 0 Glycophorin A GWT1 PF06423.12 EGG12755.1 - 4 7.6 12.3 0.26 11.4 2.4 3.1 1 1 0 2 2 2 0 GWT1 HTH_32 PF13565.6 EGG12757.1 - 0.007 17.0 1.1 0.04 14.5 0.2 2.4 2 1 0 2 2 2 1 Homeodomain-like domain Clr5 PF14420.6 EGG12757.1 - 0.071 13.3 0.0 2 8.7 0.0 2.5 2 1 0 2 2 2 0 Clr5 domain HTH_38 PF13936.6 EGG12757.1 - 0.2 11.5 0.3 1.2 9.0 0.3 2.2 1 1 0 1 1 1 0 Helix-turn-helix domain zf-C2H2 PF00096.26 EGG12762.1 - 2.7e-05 24.4 8.1 0.0033 17.8 2.6 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG12762.1 - 0.003 17.9 3.7 1.1 9.8 0.4 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGG12762.1 - 0.034 14.1 0.4 0.14 12.2 0.4 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGG12762.1 - 0.11 13.4 10.1 0.11 13.4 2.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Methyltrn_RNA_3 PF02598.17 EGG12763.1 - 9.5e-94 314.1 0.0 6.1e-93 311.5 0.0 1.8 1 1 0 1 1 1 1 Putative RNA methyltransferase Hydantoinase_B PF02538.14 EGG12763.1 - 0.081 11.3 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase SLATT_fungal PF18142.1 EGG12764.1 - 2.4e-08 34.0 0.0 3.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain 2-oxoacid_dh PF00198.23 EGG12765.1 - 1.1e-48 165.7 0.0 2e-48 164.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGG12765.1 - 6.7e-18 64.3 0.1 1.4e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EGG12765.1 - 2.3e-14 53.4 0.0 4.5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EGG12765.1 - 0.15 11.9 0.0 6.1 6.8 0.0 2.9 2 1 1 3 3 3 0 Biotin-lipoyl like NAD_binding_5 PF07994.12 EGG12767.1 - 1.2e-141 471.7 0.0 1.5e-141 471.5 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EGG12767.1 - 6.8e-45 151.8 0.1 1.3e-44 150.8 0.1 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Methyltransf_23 PF13489.6 EGG12768.1 - 3.8e-15 56.1 0.0 7.8e-15 55.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG12768.1 - 4.2e-11 43.4 0.0 8.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG12768.1 - 9e-10 38.5 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG12768.1 - 5.5e-09 36.7 0.0 1.2e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG12768.1 - 6.6e-09 36.3 0.0 1.3e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EGG12768.1 - 1.7e-05 24.4 0.0 4.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain TehB PF03848.14 EGG12768.1 - 0.0031 17.0 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 EGG12768.1 - 0.0031 16.9 0.0 0.084 12.2 0.0 2.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 EGG12768.1 - 0.011 14.3 0.0 0.034 12.7 0.0 1.6 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.11 EGG12768.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) GHMP_kinases_C PF08544.13 EGG12769.1 - 2.3e-05 24.6 0.0 0.00011 22.5 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal TelA PF05816.11 EGG12769.1 - 0.015 14.4 0.9 0.024 13.7 0.9 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) GHMP_kinases_N PF00288.26 EGG12769.1 - 0.019 15.2 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases N terminal domain DUF2938 PF11158.8 EGG12769.1 - 0.15 11.5 0.2 0.31 10.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) BEX PF04538.12 EGG12769.1 - 0.15 12.6 0.1 0.27 11.8 0.1 1.3 1 0 0 1 1 1 0 Brain expressed X-linked like family PI3K_1B_p101 PF10486.9 EGG12770.1 - 0.082 10.7 3.3 0.13 10.0 3.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pyr_redox_2 PF07992.14 EGG12771.1 - 3e-51 174.4 0.1 3.8e-51 174.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EGG12771.1 - 2.7e-14 52.8 0.0 6.7e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EGG12771.1 - 3.8e-13 49.8 1.0 2.7e-09 37.4 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EGG12771.1 - 8.2e-07 28.9 0.0 2.9e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 EGG12771.1 - 5.2e-06 26.9 0.1 1.5e-05 25.4 0.1 1.8 1 0 0 1 1 1 1 Reductase C-terminal Pyr_redox_3 PF13738.6 EGG12771.1 - 1.7e-05 24.3 0.0 0.092 12.0 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGG12771.1 - 0.05 12.7 0.0 0.45 9.6 0.0 2.3 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGG12771.1 - 0.13 12.3 0.3 35 4.3 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding BTB PF00651.31 EGG12776.1 - 1.9e-08 34.5 0.1 0.00057 20.1 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain CMAS PF02353.20 EGG12778.1 - 4.8e-34 117.9 0.1 7e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EGG12778.1 - 2.2e-14 53.9 0.0 3.5e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG12778.1 - 3.3e-13 49.8 0.0 4.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG12778.1 - 3.5e-13 50.1 0.0 9.5e-13 48.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG12778.1 - 3.7e-11 43.0 0.0 5.3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG12778.1 - 1.8e-10 41.4 0.0 3.5e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG12778.1 - 1.5e-07 31.1 0.0 3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EGG12778.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltr_RsmB-F PF01189.17 EGG12778.1 - 0.00067 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F TehB PF03848.14 EGG12778.1 - 0.002 17.6 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB YfkB PF08756.10 EGG12778.1 - 0.0056 16.5 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 YfkB-like domain RrnaAD PF00398.20 EGG12778.1 - 0.0069 15.5 0.0 0.02 14.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EGG12778.1 - 0.016 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EGG12778.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.19 EGG12778.1 - 0.036 14.2 0.0 0.17 12.0 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EGG12778.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PIRT PF15099.6 EGG12779.1 - 0.078 12.6 0.2 0.22 11.1 0.2 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family AWPM-19 PF05512.11 EGG12779.1 - 7 6.8 10.6 11 6.2 2.8 2.4 1 1 0 2 2 2 0 AWPM-19-like family F-box PF00646.33 EGG12780.1 - 1.3 9.0 4.1 10 6.1 0.1 3.1 3 0 0 3 3 3 0 F-box domain Alpha-amylase PF00128.24 EGG12782.1 - 5.9e-16 58.9 6.5 1.2e-13 51.4 1.6 3.4 3 1 0 3 3 3 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EGG12782.1 - 4.1e-14 52.9 0.0 8.1e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EGG12782.1 - 6.7e-05 22.5 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 FSH1 PF03959.13 EGG12783.1 - 8.4e-11 41.9 0.1 4e-06 26.6 0.0 3.1 1 1 1 2 2 2 2 Serine hydrolase (FSH1) DUF5560 PF17715.1 EGG12783.1 - 0.048 13.1 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5560) zf-CCHC PF00098.23 EGG12784.1 - 2.1e-09 37.0 32.4 0.00018 21.4 0.5 5.1 5 1 0 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.6 EGG12784.1 - 0.0048 16.7 0.9 0.0048 16.7 0.9 4.0 4 0 0 4 4 4 2 Zinc knuckle Porphobil_deam PF01379.20 EGG12786.1 - 2e-76 256.0 0.0 3.4e-76 255.3 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EGG12786.1 - 1.4e-17 63.8 0.0 3e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Band_7 PF01145.25 EGG12788.1 - 1.8e-23 83.5 5.5 1.9e-23 83.4 4.3 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EGG12788.1 - 1.5e-05 24.2 4.7 2.1e-05 23.8 4.7 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial AAA_lid_4 PF17864.1 EGG12788.1 - 0.024 14.4 2.2 0.061 13.1 0.1 2.4 1 1 0 2 2 2 0 RuvB AAA lid domain Polysacc_deac_1 PF01522.21 EGG12789.1 - 1.9e-26 92.4 0.0 3e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase PUFD PF16553.5 EGG12792.1 - 0.029 14.5 0.2 0.073 13.2 0.2 1.6 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain Chitin_synth_2 PF03142.15 EGG12793.1 - 2.6e-247 821.6 0.0 3.7e-247 821.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 EGG12793.1 - 5.8e-13 49.3 0.0 7.9e-12 45.5 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGG12793.1 - 5.2e-12 46.1 5.5 1.7e-11 44.4 5.5 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EGG12793.1 - 0.0031 17.0 0.1 0.053 13.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGG12793.1 - 0.032 14.0 0.0 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 PRIMA1 PF16101.5 EGG12794.1 - 0.018 15.0 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Abhydrolase_6 PF12697.7 EGG12794.1 - 0.048 14.2 0.0 0.12 13.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family CAP_N PF01213.19 EGG12794.1 - 0.093 12.2 0.8 0.15 11.5 0.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TNFR_16_TM PF18422.1 EGG12794.1 - 0.46 10.5 2.4 1.6 8.8 2.4 1.9 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain RRM_1 PF00076.22 EGG12795.1 - 1.1e-52 175.7 0.1 7.8e-19 67.3 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG12795.1 - 4.5e-09 36.0 0.0 0.00015 21.4 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG12795.1 - 0.00038 20.4 0.0 9.8 6.3 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EGG12795.1 - 0.00046 20.0 0.0 0.012 15.5 0.0 2.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif Cas_Cas2CT1978 PF09707.10 EGG12795.1 - 0.0051 16.8 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 EGG12795.1 - 0.015 15.4 0.0 0.34 11.1 0.0 2.9 3 1 0 3 3 3 0 RNA recognition motif DivIC PF04977.15 EGG12795.1 - 2.1 8.2 5.6 4.3 7.2 5.6 1.5 1 0 0 1 1 1 0 Septum formation initiator RRM_2 PF04059.12 EGG12796.1 - 3.1e-33 113.8 0.6 5.3e-33 113.1 0.6 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EGG12796.1 - 0.13 12.1 0.3 0.45 10.4 0.3 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAS_9 PF13426.7 EGG12798.1 - 0.089 13.1 0.3 0.51 10.6 0.0 2.5 3 0 0 3 3 3 0 PAS domain HTH_22 PF13309.6 EGG12798.1 - 0.17 12.0 0.0 0.76 9.9 0.0 2.1 1 0 0 1 1 1 0 HTH domain Sigma54_activ_2 PF14532.6 EGG12798.1 - 0.17 12.0 1.0 0.76 9.9 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain CxC1 PF18802.1 EGG12800.1 - 2.1e-16 59.9 3.2 3.5e-15 56.0 0.0 2.3 1 1 1 2 2 2 2 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG12800.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases Rad60-SLD PF11976.8 EGG12801.1 - 1.1e-05 25.2 0.0 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGG12801.1 - 0.005 16.6 0.0 0.0064 16.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGG12802.1 - 6.3e-16 58.0 0.0 1.8e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGG12802.1 - 4.8e-09 35.9 0.0 0.00016 21.3 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family UN_NPL4 PF11543.8 EGG12802.1 - 0.002 18.6 0.0 2.2 8.8 0.0 2.5 3 0 0 3 3 3 2 Nuclear pore localisation protein NPL4 Glyoxal_oxid_N PF07250.11 EGG12803.1 - 4.3e-31 108.0 0.0 6.4e-30 104.1 0.0 2.7 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EGG12803.1 - 4.3e-19 68.6 0.1 1e-18 67.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) RCC1_2 PF13540.6 EGG12803.1 - 0.093 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 EGG12803.1 - 0.13 12.3 0.1 38 4.4 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain FixO PF02433.15 EGG12803.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Wzz PF02706.15 EGG12804.1 - 0.14 12.5 0.2 0.14 12.5 0.2 3.1 4 0 0 4 4 4 0 Chain length determinant protein TB2_DP1_HVA22 PF03134.19 EGG12805.1 - 7.5e-31 105.9 5.9 7.5e-31 105.9 5.9 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Hum_adeno_E3A PF05393.11 EGG12805.1 - 0.23 11.4 4.0 0.11 12.5 1.6 1.6 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Phage_holin_3_6 PF07332.11 EGG12805.1 - 0.26 11.3 2.7 0.38 10.8 2.7 1.4 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III tRNA-synt_1b PF00579.25 EGG12808.1 - 9.1e-22 77.7 0.0 3.6e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Septin PF00735.18 EGG12809.1 - 7.8e-96 320.6 0.0 7.8e-96 320.6 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EGG12809.1 - 2.2e-06 27.8 0.0 5.9e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG12809.1 - 0.00012 22.0 5.1 0.00013 21.9 0.5 2.5 3 0 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 EGG12809.1 - 0.031 13.6 1.0 0.23 10.7 1.0 2.3 1 1 0 1 1 1 0 AIG1 family AAA_19 PF13245.6 EGG12809.1 - 0.032 14.6 0.0 0.16 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGG12809.1 - 0.039 14.5 0.8 0.091 13.3 0.0 2.0 2 1 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 EGG12809.1 - 0.065 12.8 0.3 0.72 9.4 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EGG12809.1 - 0.075 13.3 0.1 0.33 11.2 0.1 2.2 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGG12809.1 - 0.11 11.8 0.3 0.24 10.7 0.3 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.6 EGG12809.1 - 0.26 11.5 0.1 0.26 11.5 0.1 2.4 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EGG12809.1 - 1.5 8.8 6.0 5.4 7.1 0.1 3.2 2 1 1 3 3 3 0 Dynamin family Cnn_1N PF07989.11 EGG12809.1 - 2.4 8.4 12.8 24 5.2 8.8 2.8 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 SMC_N PF02463.19 EGG12811.1 - 3.6e-26 92.0 22.8 5.1e-26 91.5 22.7 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGG12811.1 - 4.7e-25 88.2 0.0 1.1e-24 87.0 0.0 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EGG12811.1 - 2.7e-12 47.6 30.9 2.7e-12 47.6 30.9 4.5 2 1 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EGG12811.1 - 9.9e-12 45.2 5.5 9.9e-12 45.2 5.5 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 EGG12811.1 - 4.1e-07 30.1 2.5 5.9e-07 29.6 0.1 2.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system COG2 PF06148.11 EGG12811.1 - 0.0024 17.9 3.6 0.0024 17.9 3.6 5.1 4 1 2 6 6 6 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4201 PF13870.6 EGG12811.1 - 0.011 15.5 15.7 0.011 15.5 15.7 4.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) AAA_29 PF13555.6 EGG12811.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DASH_Hsk3 PF08227.11 EGG12811.1 - 1.1 9.7 9.2 0.15 12.4 1.1 3.3 5 0 0 5 5 5 0 DASH complex subunit Hsk3 like RNA_pol_L_2 PF13656.6 EGG12812.1 - 1.5e-30 104.8 0.0 2e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGG12812.1 - 3.5e-10 39.2 0.0 5.9e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain XPA_C PF05181.12 EGG12812.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 XPA protein C-terminus TPR_MLP1_2 PF07926.12 EGG12813.1 - 0.0007 19.7 36.3 0.35 10.9 13.6 4.1 3 1 1 4 4 4 3 TPR/MLP1/MLP2-like protein DUF1216 PF06746.11 EGG12813.1 - 0.0057 16.7 4.0 0.0057 16.7 4.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1216) Hormone_1 PF00103.20 EGG12813.1 - 0.1 12.3 10.0 0.23 11.2 0.6 2.8 3 0 0 3 3 3 0 Somatotropin hormone family Myb_DNA-bind_3 PF12776.7 EGG12813.1 - 0.18 12.8 3.8 0.16 13.0 1.6 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain ADIP PF11559.8 EGG12813.1 - 0.3 11.2 26.3 1.8 8.6 17.4 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 EGG12813.1 - 0.46 10.3 24.7 7.6 6.4 6.9 5.0 3 1 2 5 5 5 0 Septum formation initiator Med9 PF07544.13 EGG12813.1 - 0.49 10.5 24.3 2.8 8.1 3.3 4.2 3 2 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Phage_GPO PF05929.11 EGG12813.1 - 1.1 8.8 20.4 1.9 8.0 4.2 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase GyrB_insert PF18053.1 EGG12813.1 - 1.3 8.9 15.8 0.4 10.6 2.6 3.3 2 1 0 3 3 3 0 DNA gyrase B subunit insert domain PIN_12 PF16289.5 EGG12813.1 - 1.7 9.1 15.9 0.94 10.0 9.7 2.2 1 1 1 2 2 2 0 PIN domain Spc7 PF08317.11 EGG12813.1 - 1.7 7.5 32.4 0.58 9.0 13.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Rx_N PF18052.1 EGG12813.1 - 1.9 8.8 15.1 0.51 10.6 1.9 2.9 4 0 0 4 4 2 0 Rx N-terminal domain FliD_N PF02465.18 EGG12813.1 - 2.3 9.0 13.5 2.1 9.1 0.7 3.3 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Seryl_tRNA_N PF02403.22 EGG12813.1 - 2.7 8.3 26.5 0.51 10.6 4.8 4.0 2 1 3 5 5 5 0 Seryl-tRNA synthetase N-terminal domain L31 PF09784.9 EGG12813.1 - 3.7 8.0 6.2 4 7.9 2.0 2.7 1 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 Phage_GP20 PF06810.11 EGG12813.1 - 3.9 7.3 21.0 2.3 8.0 8.1 2.8 1 1 0 2 2 2 0 Phage minor structural protein GP20 Phasin_2 PF09361.10 EGG12813.1 - 4.9 7.5 13.7 0.055 13.7 2.9 2.9 3 1 1 4 4 3 0 Phasin protein Atg14 PF10186.9 EGG12813.1 - 5.6 5.9 20.5 44 3.0 20.5 2.2 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 EGG12813.1 - 6.1 5.6 31.9 7.3 5.3 19.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Prominin PF05478.11 EGG12813.1 - 7.2 4.4 17.3 72 1.1 17.5 1.8 1 1 0 1 1 1 0 Prominin Laminin_II PF06009.12 EGG12813.1 - 7.7 6.5 18.0 4.6 7.3 5.6 3.1 1 1 1 2 2 2 0 Laminin Domain II DUF1542 PF07564.11 EGG12813.1 - 7.7 6.7 15.2 1.1 9.4 0.5 3.1 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1542) Sec34 PF04136.15 EGG12813.1 - 9.7 6.1 19.6 1.7 8.5 5.5 3.0 3 1 0 3 3 2 0 Sec34-like family Myb_DNA-bind_3 PF12776.7 EGG12814.1 - 2.1e-24 86.3 1.5 2.1e-24 86.3 1.5 2.1 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGG12814.1 - 3e-06 27.5 0.7 7.9e-06 26.2 0.2 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 EGG12814.1 - 0.073 13.4 0.5 0.16 12.2 0.5 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein DUF573 PF04504.14 EGG12814.1 - 0.088 13.5 0.4 0.2 12.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF573 DUF2252 PF10009.9 EGG12814.1 - 0.092 11.8 0.3 0.15 11.1 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) SNF2_N PF00176.23 EGG12815.1 - 4.4e-64 216.4 2.5 1.2e-63 215.0 2.5 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 EGG12815.1 - 4.6e-20 71.5 1.8 1.7e-19 69.7 1.3 2.2 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.31 EGG12815.1 - 1.8e-18 66.9 0.1 1.7e-16 60.5 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 EGG12815.1 - 1.9e-16 60.2 14.0 7e-16 58.3 14.0 2.1 1 0 0 1 1 1 1 HSA SnAC PF14619.6 EGG12815.1 - 1.8e-12 47.6 0.1 1.8e-12 47.6 0.1 3.9 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex DUF3734 PF12536.8 EGG12815.1 - 0.052 13.9 5.5 8.7 6.7 0.6 3.6 3 0 0 3 3 3 0 Patatin phospholipase PPTA PF01239.22 EGG12816.1 - 4.3e-11 42.2 3.0 1.5e-06 27.8 0.6 3.3 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat MA3 PF02847.17 EGG12817.1 - 3.2e-28 98.0 0.0 6.3e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 EGG12817.1 - 5.6e-12 45.8 1.1 1.2e-11 44.7 0.1 2.0 2 0 0 2 2 2 1 MIF4G domain Pkinase PF00069.25 EGG12818.1 - 1.6e-26 93.2 0.0 1.9e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG12818.1 - 1.4e-13 50.8 0.0 1.8e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG12818.1 - 9e-07 28.0 0.0 1.1e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGG12818.1 - 0.001 19.0 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family RR_TM4-6 PF06459.12 EGG12819.1 - 0.15 11.9 3.8 0.19 11.5 3.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Acetyltransf_3 PF13302.7 EGG12821.1 - 1.4e-18 67.9 0.0 2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG12821.1 - 3.1e-06 27.1 0.0 5.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGG12821.1 - 0.01 16.2 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AflR PF08493.10 EGG12824.1 - 0.02 14.4 1.7 0.037 13.5 1.7 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein TFIIF_alpha PF05793.12 EGG12824.1 - 0.091 11.3 12.1 0.036 12.7 9.3 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4203 PF13886.6 EGG12826.1 - 1.4e-45 155.5 26.2 1.8e-45 155.1 26.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DKCLD PF08068.12 EGG12827.1 - 1.1e-33 115.1 1.4 2.3e-32 110.9 0.4 3.0 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.18 EGG12827.1 - 2.3e-24 86.5 0.3 2.2e-21 76.8 0.3 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EGG12827.1 - 6.3e-23 80.7 0.4 1.3e-22 79.7 0.4 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EGG12827.1 - 5e-22 77.7 1.4 8.2e-22 77.0 1.4 1.4 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EGG12827.1 - 0.0035 17.6 0.0 0.0084 16.4 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain SAE2 PF08573.10 EGG12828.1 - 2.6e-08 35.0 9.3 9.7e-06 26.7 1.4 4.1 3 1 1 4 4 4 2 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF356 PF04009.12 EGG12831.1 - 0.1 12.9 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF356) RNase_T PF00929.24 EGG12832.1 - 1.8e-15 57.9 0.0 4.3e-15 56.7 0.0 1.6 1 1 0 1 1 1 1 Exonuclease Nucleoporin_C PF03177.14 EGG12833.1 - 7.3e-92 309.0 5.7 1e-91 308.6 5.7 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EGG12833.1 - 6.4e-15 54.8 0.2 2.5e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 Nup133 N terminal like Gpi1 PF05024.15 EGG12834.1 - 1.9e-55 187.9 9.8 2.7e-55 187.4 9.8 1.2 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) CxC6 PF18721.1 EGG12835.1 - 2.2e-21 75.9 3.0 6.1e-21 74.5 3.0 1.8 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 EGG12835.1 - 2e-14 53.7 6.3 1.6e-13 50.7 6.3 2.4 1 1 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases BDV_P10 PF06515.11 EGG12835.1 - 0.12 12.4 0.1 0.33 11.0 0.1 1.7 1 0 0 1 1 1 0 Borna disease virus P10 protein Ras PF00071.22 EGG12836.1 - 0.0022 17.6 0.0 1.2 8.7 0.0 2.0 1 1 1 2 2 2 2 Ras family polyprenyl_synt PF00348.17 EGG12841.1 - 2.9e-43 147.8 0.0 3.5e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ank_4 PF13637.6 EGG12844.1 - 2.5e-14 53.4 0.2 2.2e-07 31.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG12844.1 - 4.4e-10 40.0 0.0 2.5e-09 37.6 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG12844.1 - 4.6e-08 33.2 0.1 9.6e-07 29.0 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG12844.1 - 1.6e-07 31.0 0.0 0.00012 22.2 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EGG12844.1 - 2e-07 31.2 0.1 3.8e-05 23.9 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat TAF PF02969.17 EGG12844.1 - 0.084 13.1 0.2 4.3 7.6 0.0 2.7 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) Prefoldin PF02996.17 EGG12845.1 - 1.4e-23 83.1 0.9 1.9e-23 82.6 0.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF1664 PF07889.12 EGG12845.1 - 0.41 10.7 2.9 3.5 7.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 EGG12845.1 - 0.61 10.3 5.4 0.32 11.2 1.0 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Transpos_assoc PF13963.6 EGG12846.1 - 4.6 7.6 5.8 15 6.0 2.7 2.2 1 1 1 2 2 2 0 Transposase-associated domain DUF998 PF06197.13 EGG12847.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) PI3K_1B_p101 PF10486.9 EGG12849.1 - 0.029 12.2 21.3 0.041 11.7 21.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit AF-4 PF05110.13 EGG12849.1 - 0.036 12.2 29.1 0.06 11.5 29.1 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 EGG12849.1 - 0.76 8.3 19.4 1.2 7.6 19.4 1.3 1 0 0 1 1 1 0 Macoilin family SOBP PF15279.6 EGG12849.1 - 1.3 9.6 8.6 2.2 8.8 8.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein NAM-associated PF14303.6 EGG12849.1 - 6.1 7.5 19.4 16 6.1 19.4 1.8 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Pribosyltran PF00156.27 EGG12850.1 - 3.8e-14 52.5 0.1 5.4e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Hat1_N PF10394.9 EGG12851.1 - 1.1e-50 172.1 0.7 1.8e-50 171.3 0.7 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 EGG12851.1 - 0.00038 20.7 0.0 0.0014 18.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 EGG12851.1 - 0.0047 16.6 0.1 0.0076 15.9 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family Scm3 PF10384.9 EGG12851.1 - 0.059 13.1 0.5 0.48 10.2 0.0 2.3 2 0 0 2 2 2 0 Centromere protein Scm3 Gemini_mov PF01708.16 EGG12852.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein TMEM154 PF15102.6 EGG12853.1 - 0.0053 16.7 3.0 0.06 13.2 3.0 2.2 1 1 0 1 1 1 1 TMEM154 protein family BatA PF07584.11 EGG12853.1 - 0.079 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF1691 PF07950.11 EGG12854.1 - 7.2e-08 33.1 1.2 0.00013 22.7 0.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) SH3BGR PF04908.15 EGG12855.1 - 0.1 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein SPX PF03105.19 EGG12856.1 - 1.5e-27 97.5 13.9 3.1e-10 40.5 0.1 3.5 1 1 2 3 3 3 3 SPX domain GDPD PF03009.17 EGG12856.1 - 7.3e-09 35.7 0.0 7.2e-08 32.5 0.0 2.5 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Telomere_res PF16684.5 EGG12856.1 - 0.006 16.1 0.2 0.45 9.9 0.7 2.3 2 0 0 2 2 2 1 Telomere resolvase CDC37_C PF08564.10 EGG12856.1 - 0.091 12.9 0.2 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 Cdc37 C terminal domain JSRP PF15312.6 EGG12859.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein Rhodanese PF00581.20 EGG12860.1 - 1.9e-13 50.9 0.0 2.4e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain XAP5 PF04921.14 EGG12861.1 - 0.11 12.3 7.1 0.14 12.0 7.1 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Paramyxo_ncap PF00973.19 EGG12861.1 - 0.2 10.5 2.6 0.24 10.3 2.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC45 PF02724.14 EGG12861.1 - 0.21 9.9 3.8 0.23 9.7 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Rtf2 PF04641.12 EGG12861.1 - 0.22 10.8 7.2 0.26 10.6 7.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CPSF100_C PF13299.6 EGG12861.1 - 0.32 11.2 4.9 0.4 10.8 4.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC27 PF09507.10 EGG12862.1 - 0.0018 17.8 15.8 0.0018 17.8 15.8 2.2 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 Pannexin_like PF12534.8 EGG12862.1 - 2.5 7.1 4.7 5.3 6.0 4.7 1.5 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 BUD22 PF09073.10 EGG12862.1 - 2.6 7.3 36.8 0.3 10.4 19.7 2.3 2 0 0 2 2 2 0 BUD22 UbiA PF01040.18 EGG12863.1 - 1.6e-48 165.2 13.7 2.2e-48 164.8 13.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ost4 PF10215.9 EGG12863.1 - 0.018 14.8 0.1 0.075 12.9 0.1 2.1 1 0 0 1 1 1 0 Oligosaccaryltransferase Ctr PF04145.15 EGG12864.1 - 8.8 6.9 0.0 8.8 6.9 0.0 3.3 2 2 0 2 2 2 0 Ctr copper transporter family Sulf_transp PF04143.14 EGG12865.1 - 5.1e-06 26.3 12.8 7.6e-05 22.4 6.3 3.1 3 1 0 3 3 3 2 Sulphur transport RIC1 PF07064.13 EGG12865.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 RIC1 p450 PF00067.22 EGG12867.1 - 2.2e-50 171.8 0.0 3e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ureidogly_lyase PF04115.12 EGG12868.1 - 2e-42 145.1 0.0 2.5e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase Allantoicase PF03561.15 EGG12868.1 - 0.0081 16.1 0.2 0.014 15.4 0.2 1.4 1 0 0 1 1 1 1 Allantoicase repeat Peptidase_C12 PF01088.21 EGG12869.1 - 3.9e-60 203.2 0.0 4.5e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SKN1 PF03935.15 EGG12870.1 - 1.4e-202 673.6 2.6 1.6e-202 673.4 2.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Drf_FH1 PF06346.12 EGG12871.1 - 0.76 9.5 6.1 0.72 9.6 1.5 2.5 2 0 0 2 2 2 0 Formin Homology Region 1 Glyco_hydro_3_C PF01915.22 EGG12872.1 - 3.4e-48 164.3 0.2 6.9e-48 163.3 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGG12872.1 - 3.5e-38 131.8 0.0 5.6e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGG12872.1 - 6.1e-23 80.7 0.9 1.2e-22 79.8 0.9 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain tRNA-synt_1c PF00749.21 EGG12876.1 - 1.7e-106 355.7 0.1 2.5e-106 355.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGG12876.1 - 8.8e-34 116.9 0.1 1.9e-33 115.8 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 EGG12876.1 - 0.0012 19.0 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG12876.1 - 0.0028 17.8 0.0 0.091 13.0 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG12876.1 - 0.0036 17.3 0.1 0.0099 15.9 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AIMP2_LysRS_bd PF16780.5 EGG12876.1 - 0.16 11.7 0.2 0.32 10.8 0.2 1.5 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain Sec3_C PF09763.9 EGG12877.1 - 0.0075 14.7 1.8 0.012 14.1 1.8 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 DUF4164 PF13747.6 EGG12877.1 - 0.0093 16.2 4.1 0.018 15.3 4.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) Baculo_PEP_C PF04513.12 EGG12877.1 - 0.03 14.3 0.4 0.049 13.7 0.4 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mod_r PF07200.13 EGG12877.1 - 0.032 14.3 5.5 0.053 13.6 5.5 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.6 EGG12877.1 - 0.033 13.5 5.6 0.057 12.8 5.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prominin PF05478.11 EGG12877.1 - 0.076 11.0 2.6 0.1 10.5 2.6 1.1 1 0 0 1 1 1 0 Prominin HIP1_clath_bdg PF16515.5 EGG12877.1 - 0.09 13.4 5.2 0.21 12.2 5.2 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Noelin-1 PF12308.8 EGG12877.1 - 0.092 12.7 2.5 0.22 11.5 2.5 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein KxDL PF10241.9 EGG12877.1 - 0.11 12.7 2.7 0.26 11.6 2.7 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein Ntox28 PF15605.6 EGG12877.1 - 0.13 12.5 1.2 0.27 11.5 1.2 1.6 1 0 0 1 1 1 0 Bacterial toxin 28 DUF883 PF05957.13 EGG12877.1 - 0.19 12.4 2.1 0.36 11.5 2.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Tweety PF04906.13 EGG12877.1 - 0.21 10.2 0.4 0.3 9.7 0.4 1.1 1 0 0 1 1 1 0 Tweety Spectrin PF00435.21 EGG12877.1 - 0.3 11.6 3.8 0.61 10.6 2.9 1.9 1 1 1 2 2 2 0 Spectrin repeat Fmp27_WPPW PF10359.9 EGG12877.1 - 0.35 9.7 7.7 0.48 9.2 7.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1664 PF07889.12 EGG12877.1 - 0.58 10.2 3.0 1.8 8.7 2.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 EGG12877.1 - 1 9.6 6.0 0.23 11.7 2.0 2.1 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 EGG12877.1 - 2.9 8.0 5.4 1.4 9.1 0.9 2.2 2 0 0 2 2 2 0 bZIP transcription factor V_ATPase_I PF01496.19 EGG12877.1 - 3.2 5.6 6.0 4.3 5.1 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 EGG12879.1 - 0.12 13.0 0.1 0.43 11.2 0.1 1.9 1 0 0 1 1 1 0 SlyX ADIP PF11559.8 EGG12879.1 - 1.3 9.1 4.5 0.81 9.8 0.2 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Pox_A21 PF05323.12 EGG12880.1 - 6.6 7.4 10.3 40 4.8 10.3 2.0 1 1 0 1 1 1 0 Poxvirus A21 Protein TRAPP PF04051.16 EGG12881.1 - 1.1e-31 109.6 0.0 1.3e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component tRNA-synt_2b PF00587.25 EGG12882.1 - 1.3e-18 67.6 0.0 2.1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_hydro_28 PF00295.17 EGG12884.1 - 1.6e-21 76.7 5.0 1.6e-21 76.7 5.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EGG12884.1 - 0.0011 18.8 8.2 0.0017 18.3 0.1 3.0 2 1 0 3 3 3 1 Pectate lyase superfamily protein DUF723 PF05265.13 EGG12884.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF723) Pkinase PF00069.25 EGG12885.1 - 2.3e-43 148.5 0.2 1.2e-20 74.0 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG12885.1 - 1.3e-12 47.6 0.3 2e-08 33.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF604 PF04646.12 EGG12888.1 - 2.9e-15 56.4 0.1 5.4e-15 55.5 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 EGG12888.1 - 3.2e-08 33.3 0.0 6.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Fringe-like Tyrosinase PF00264.20 EGG12889.1 - 6.7e-13 49.4 3.4 9.3e-13 49.0 3.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3605 PF12239.8 EGG12890.1 - 1.3e-17 64.5 7.2 1.2e-13 51.6 1.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) DNA_meth_N PF18284.1 EGG12890.1 - 0.013 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 DNA methylase N-terminal domain PRD PF00874.20 EGG12890.1 - 0.11 12.8 0.5 13 6.2 0.3 2.5 2 0 0 2 2 2 0 PRD domain SnoaL_2 PF12680.7 EGG12891.1 - 9.2e-06 26.2 0.1 1.3e-05 25.8 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EGG12891.1 - 0.029 14.8 0.0 0.04 14.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) Spc24 PF08286.11 EGG12892.1 - 4e-05 23.8 2.6 0.002 18.4 0.0 2.3 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 APG6_N PF17675.1 EGG12892.1 - 0.00059 20.4 9.1 0.0009 19.8 9.1 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Spc7 PF08317.11 EGG12892.1 - 0.0014 17.5 10.0 0.002 17.1 10.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4618 PF15397.6 EGG12892.1 - 0.0019 17.7 2.4 0.0026 17.2 2.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Exonuc_VII_L PF02601.15 EGG12892.1 - 0.015 14.9 1.0 0.02 14.5 1.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2968 PF11180.8 EGG12892.1 - 0.018 14.7 7.3 0.026 14.1 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Atg14 PF10186.9 EGG12892.1 - 0.034 13.2 1.6 0.038 13.1 1.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 EGG12892.1 - 0.7 10.0 8.5 1.1 9.4 8.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2951 PF11166.8 EGG12892.1 - 2.5 8.4 5.8 16 5.8 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) TMPIT PF07851.13 EGG12892.1 - 3.5 6.8 5.5 5.4 6.2 5.5 1.4 1 1 0 1 1 1 0 TMPIT-like protein YlqD PF11068.8 EGG12892.1 - 4.1 7.8 9.6 2.2 8.7 4.4 2.2 1 1 0 2 2 2 0 YlqD protein DivIC PF04977.15 EGG12892.1 - 5.1 6.9 7.8 8.1 6.3 0.3 2.4 1 1 1 2 2 2 0 Septum formation initiator Tim17 PF02466.19 EGG12893.1 - 1.1e-31 109.5 7.3 1.4e-31 109.2 7.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3600 PF12207.8 EGG12894.1 - 0.057 13.4 0.0 0.059 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) RPN6_N PF18055.1 EGG12897.1 - 0.018 15.4 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain Arrestin_N PF00339.29 EGG12899.1 - 2.9e-05 24.1 0.0 7.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Ins_P5_2-kin PF06090.12 EGG12902.1 - 1.8e-63 215.0 0.0 2.1e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase FAR1 PF03101.15 EGG12904.1 - 0.00062 20.4 0.0 0.001 19.7 0.0 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 EGG12904.1 - 0.13 12.7 0.1 0.43 11.0 0.0 1.8 1 1 0 1 1 1 0 Transcription factor AFT BC10 PF06726.12 EGG12905.1 - 4.6e-08 33.2 11.1 4.6e-08 33.2 11.1 2.2 2 0 0 2 2 2 1 Bladder cancer-related protein BC10 RFC1 PF08519.12 EGG12907.1 - 2.2e-54 183.9 0.0 1.5e-53 181.2 0.0 2.6 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EGG12907.1 - 1.7e-16 60.3 0.0 6.5e-16 58.5 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EGG12907.1 - 4.5e-10 40.1 0.4 1.8e-09 38.1 0.1 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGG12907.1 - 2.5e-08 34.0 0.1 7.1e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EGG12907.1 - 0.00019 21.7 0.1 0.0016 18.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG12907.1 - 0.00027 21.5 0.1 0.00073 20.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG12907.1 - 0.0026 18.2 0.0 0.021 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EGG12907.1 - 0.0042 17.1 0.0 0.016 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGG12907.1 - 0.02 15.2 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PTCB-BRCT PF12738.7 EGG12907.1 - 0.022 14.7 0.1 0.056 13.4 0.1 1.7 1 0 0 1 1 1 0 twin BRCT domain RuvB_N PF05496.12 EGG12907.1 - 0.023 14.4 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGG12907.1 - 0.034 14.1 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EGG12907.1 - 0.035 14.0 0.5 0.12 12.3 0.4 1.9 1 1 1 2 2 2 0 NTPase PBP1_TM PF14812.6 EGG12907.1 - 0.052 13.9 24.1 0.05 14.0 15.8 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_33 PF13671.6 EGG12907.1 - 0.065 13.4 0.1 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGG12907.1 - 0.096 12.6 0.0 6.3 6.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Colicin PF01024.19 EGG12908.1 - 0.13 12.2 7.2 3.6 7.5 1.6 2.5 2 0 0 2 2 2 0 Colicin pore forming domain Pkinase PF00069.25 EGG12910.1 - 2.6e-48 164.7 0.0 4e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 EGG12910.1 - 1.2e-40 138.6 1.1 2.5e-40 137.6 1.1 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EGG12910.1 - 9.6e-25 87.3 0.0 1.9e-24 86.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG12910.1 - 6.9e-05 21.8 0.0 0.00019 20.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EGG12910.1 - 0.0062 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGG12910.1 - 0.015 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Actin PF00022.19 EGG12911.1 - 6.7e-43 146.8 0.0 5.8e-23 81.2 0.0 2.2 2 0 0 2 2 2 2 Actin DUF2781 PF10914.8 EGG12911.1 - 0.052 14.0 0.1 0.093 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) Glyco_hydro_28 PF00295.17 EGG12912.1 - 8.1e-27 94.1 0.0 6e-22 78.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EGG12912.1 - 3.7e-05 23.7 0.5 0.00046 20.1 0.5 2.6 1 1 0 1 1 1 1 Pectate lyase superfamily protein Hydrolase_6 PF13344.6 EGG12913.1 - 1.9e-22 79.3 0.0 4.7e-22 78.0 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGG12913.1 - 2.1e-21 75.7 0.0 4.1e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EGG12913.1 - 0.03 14.4 0.0 0.074 13.1 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG12913.1 - 0.052 13.8 0.0 5.2 7.3 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase AATF-Che1 PF13339.6 EGG12914.1 - 2.8 8.6 6.7 1.4 9.6 3.1 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor RMI1_N PF08585.12 EGG12914.1 - 4.5 7.0 6.7 1.1 8.9 0.1 2.4 3 0 0 3 3 3 0 RecQ mediated genome instability protein CxC1 PF18802.1 EGG12916.1 - 0.064 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases ParE_toxin PF05016.15 EGG12916.1 - 0.93 10.2 4.0 9.5 6.9 0.2 3.1 2 1 1 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE HbrB PF08539.11 EGG12917.1 - 2.2e-22 79.8 0.2 4.4e-22 78.9 0.2 1.5 1 0 0 1 1 1 1 HbrB-like NapD PF03927.13 EGG12917.1 - 0.037 14.1 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 NapD protein Protoglobin PF11563.8 EGG12918.1 - 0.048 13.5 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Protoglobin Ribosomal_60s PF00428.19 EGG12918.1 - 0.17 12.5 0.0 0.28 11.8 0.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein GET2 PF08690.10 EGG12920.1 - 2.9e-14 53.5 0.0 4.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 GET complex subunit GET2 CAML PF14963.6 EGG12920.1 - 4.6e-05 23.7 0.1 6.8e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand WD40 PF00400.32 EGG12921.1 - 3e-34 116.5 15.4 2.5e-06 28.1 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 EGG12921.1 - 5.5e-09 35.2 2.1 0.015 14.0 0.0 4.6 4 1 1 5 5 5 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGG12921.1 - 0.00036 20.8 0.0 2 8.8 0.0 4.4 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG12921.1 - 0.0018 17.6 0.1 0.27 10.5 0.0 2.8 3 0 0 3 3 3 1 WD40-like domain DUF2179 PF10035.9 EGG12922.1 - 0.016 14.9 0.1 0.056 13.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) Bromodomain PF00439.25 EGG12925.1 - 2.5e-22 78.8 0.2 2.9e-22 78.5 0.2 1.1 1 0 0 1 1 1 1 Bromodomain CoA_binding_2 PF13380.6 EGG12925.1 - 0.089 13.3 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain Bromodomain PF00439.25 EGG12926.1 - 7.1e-20 70.9 0.0 1.3e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Bcr-Abl_Oligo PF09036.10 EGG12926.1 - 0.034 14.1 0.2 9 6.4 0.1 2.5 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Lzipper-MIP1 PF14389.6 EGG12926.1 - 0.039 14.2 0.4 0.086 13.1 0.4 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 CDC73_N PF16050.5 EGG12926.1 - 0.11 11.8 0.2 0.18 11.1 0.2 1.3 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal BET PF17035.5 EGG12927.1 - 9.1e-11 41.8 0.1 1.5e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Glyco_hydro_3_C PF01915.22 EGG12928.1 - 7.4e-46 156.7 0.0 1.2e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGG12928.1 - 1e-38 133.5 0.0 1.6e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGG12928.1 - 2e-22 79.1 0.1 4.3e-22 78.0 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain HMG_box PF00505.19 EGG12929.1 - 1.3e-18 67.1 0.2 2.7e-18 66.1 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGG12929.1 - 1.5e-14 54.3 0.0 3e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain TLP1_add_C PF18313.1 EGG12930.1 - 0.038 13.9 0.0 0.099 12.6 0.0 1.7 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain Beta_propel PF09826.9 EGG12931.1 - 0.021 13.7 0.1 0.023 13.6 0.1 1.1 1 0 0 1 1 1 0 Beta propeller domain Rrp44_S1 PF17215.3 EGG12931.1 - 0.035 14.0 0.2 0.083 12.9 0.0 1.8 2 0 0 2 2 2 0 S1 domain Helicase_C PF00271.31 EGG12934.1 - 2.9e-14 53.3 0.0 7.7e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EGG12934.1 - 9.7e-13 47.6 0.3 9.7e-13 47.6 0.3 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Alpha_adaptin_C PF02296.16 EGG12935.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.5 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain BSP_II PF05432.11 EGG12937.1 - 0.05 13.3 9.8 0.44 10.2 1.8 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) WD40 PF00400.32 EGG12939.1 - 8e-27 93.0 10.1 1.5e-09 38.3 0.6 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG12939.1 - 4.7e-10 39.6 0.0 0.006 16.9 0.0 4.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG12939.1 - 1.4e-05 24.6 0.1 2.3e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 WD40-like domain PQQ_3 PF13570.6 EGG12939.1 - 0.0015 19.0 1.3 11 6.7 0.0 4.4 4 1 0 4 4 4 1 PQQ-like domain PQQ PF01011.21 EGG12939.1 - 0.018 14.9 0.8 3.2 7.8 0.0 3.8 5 0 0 5 5 5 0 PQQ enzyme repeat BBS2_Mid PF14783.6 EGG12939.1 - 0.048 13.7 0.1 7.9 6.6 0.1 3.5 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 EGG12939.1 - 0.13 11.2 0.1 3.1 6.7 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Arm PF00514.23 EGG12941.1 - 1.5e-74 244.0 25.6 1.2e-11 44.2 0.1 11.8 12 0 0 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGG12941.1 - 1.5e-18 67.0 4.5 0.0073 16.7 0.1 6.6 3 2 1 5 5 5 3 HEAT repeats HEAT PF02985.22 EGG12941.1 - 1.8e-17 61.9 9.3 0.38 11.2 0.2 9.6 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.6 EGG12941.1 - 6.9e-16 58.4 15.4 0.00035 21.0 0.2 8.4 8 1 1 9 9 9 4 HEAT-like repeat Adaptin_N PF01602.20 EGG12941.1 - 1.5e-11 43.6 5.7 3.9e-09 35.6 0.3 2.3 1 1 0 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 EGG12941.1 - 2.3e-10 40.4 7.4 1.6e-08 34.3 1.1 2.8 1 1 0 2 2 2 2 Armadillo-like KAP PF05804.12 EGG12941.1 - 3.1e-07 29.0 0.1 4.5e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EGG12941.1 - 3.6e-07 29.8 1.4 0.0077 15.6 0.4 4.3 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 EGG12941.1 - 2.6e-06 27.6 5.0 0.015 15.4 0.1 3.9 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EGG12941.1 - 1e-05 25.6 5.9 0.16 11.9 0.1 3.8 3 1 1 4 4 4 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 EGG12941.1 - 0.00058 20.0 1.5 11 6.1 0.0 4.9 2 1 5 7 7 7 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 EGG12941.1 - 0.0011 19.0 3.3 0.024 14.7 0.1 3.7 5 0 0 5 5 5 1 Spinocerebellar ataxia type 10 protein domain DUF5578 PF17741.1 EGG12941.1 - 0.0015 18.0 8.0 1.5 8.2 0.5 4.6 1 1 2 4 4 4 2 Family of unknown function (DUF5578) Vac14_Fab1_bd PF12755.7 EGG12941.1 - 0.0053 17.3 0.1 9.7 6.9 0.0 3.6 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Proteasom_PSMB PF10508.9 EGG12941.1 - 0.022 13.3 1.7 2.8 6.3 0.0 2.8 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit IFRD PF05004.13 EGG12941.1 - 0.023 13.8 3.9 2.1 7.4 0.1 3.7 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 EGG12941.1 - 0.051 14.3 8.2 1.4e+02 3.6 0.0 7.0 8 0 0 8 8 6 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 EGG12941.1 - 0.074 13.2 0.7 27 5.0 0.0 3.6 2 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF1368 PF07112.11 EGG12941.1 - 0.23 10.2 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) zf-C2H2 PF00096.26 EGG12942.1 - 0.00097 19.5 0.3 0.00097 19.5 0.3 1.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.7 EGG12942.1 - 0.0045 17.3 2.8 0.022 15.1 0.3 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGG12942.1 - 0.025 15.4 1.2 0.025 15.4 1.2 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 EGG12942.1 - 0.03 14.4 1.1 0.051 13.6 1.1 1.7 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger Cyclin PF08613.11 EGG12943.1 - 3.1e-11 43.9 1.6 7.5e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGG12943.1 - 3.5e-05 23.5 0.0 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Zn_clus PF00172.18 EGG12945.1 - 0.00018 21.5 12.2 0.0065 16.6 4.5 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps4_C PF09336.10 EGG12945.1 - 0.0079 16.2 0.3 0.017 15.1 0.3 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain Transket_pyr PF02779.24 EGG12946.1 - 1e-36 126.3 0.0 1.4e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGG12946.1 - 1.5e-32 112.1 0.0 6.9e-32 109.9 0.0 2.1 2 1 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EGG12946.1 - 0.097 13.0 0.0 0.56 10.5 0.0 2.1 1 1 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II tRNA_int_endo PF01974.17 EGG12947.1 - 1.8e-14 53.6 0.0 3.1e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Tfb2 PF03849.14 EGG12949.1 - 7.2e-124 413.3 6.0 8.6e-124 413.1 6.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EGG12949.1 - 1.9e-24 85.9 0.3 4.5e-24 84.7 0.3 1.7 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EGG12949.1 - 0.041 14.0 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Syja_N PF02383.18 EGG12950.1 - 5.7e-86 288.7 0.0 9.5e-86 288.0 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EGG12950.1 - 1e-31 109.0 0.1 2.9e-31 107.6 0.1 1.8 1 0 0 1 1 1 1 Inositol phosphatase RNA_pol_N PF01194.17 EGG12952.1 - 1.2e-32 111.9 0.4 1.5e-32 111.6 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit CFEM PF05730.11 EGG12953.1 - 1.6e-13 50.5 9.0 2.3e-13 50.0 9.0 1.2 1 0 0 1 1 1 1 CFEM domain Alk_phosphatase PF00245.20 EGG12953.1 - 0.039 12.9 0.5 0.039 12.9 0.5 1.1 1 0 0 1 1 1 0 Alkaline phosphatase Swi3 PF07962.12 EGG12954.1 - 6.3e-25 87.0 0.1 1.1e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DPBB_1 PF03330.18 EGG12955.1 - 5.6e-08 33.0 0.1 2.8e-07 30.7 0.1 2.3 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EGG12955.1 - 0.0067 16.3 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Barwin family TFIIA PF03153.13 EGG12955.1 - 0.043 13.8 17.0 0.052 13.5 17.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 EGG12955.1 - 4 6.4 20.6 5.8 5.8 20.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PPP4R2 PF09184.11 EGG12955.1 - 8.9 5.8 21.8 13 5.2 21.8 1.2 1 0 0 1 1 1 0 PPP4R2 DnaJ_C PF01556.18 EGG12956.1 - 2.2e-28 99.2 0.0 3e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGG12956.1 - 4.5e-27 93.9 0.5 7e-27 93.3 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGG12956.1 - 1.2e-13 51.2 15.2 2.3e-13 50.3 15.2 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGG12956.1 - 0.0004 20.3 11.1 0.091 12.7 1.0 2.9 3 0 0 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGG12956.1 - 0.003 17.6 4.9 0.47 10.5 1.1 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 EGG12956.1 - 0.87 10.0 8.6 0.45 10.9 4.5 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar C1_2 PF03107.16 EGG12956.1 - 1.6 9.1 4.4 2.5 8.5 0.3 2.5 2 0 0 2 2 2 0 C1 domain zf-RING_10 PF16685.5 EGG12956.1 - 1.8 8.7 5.8 2 8.6 2.8 2.4 2 1 1 3 3 3 0 zinc RING finger of MSL2 SPT_ssu-like PF11779.8 EGG12957.1 - 8.7e-12 44.5 6.9 1.2e-11 44.1 6.9 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like DUF5357 PF17310.2 EGG12958.1 - 0.06 11.9 0.2 0.079 11.5 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) DUF1776 PF08643.10 EGG12959.1 - 6e-06 25.8 0.6 1.1e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Ribosomal_S4 PF00163.19 EGG12962.1 - 3.5e-12 47.1 0.3 5e-12 46.6 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EGG12962.1 - 2.7e-11 43.0 0.0 6.4e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain Chorismate_bind PF00425.18 EGG12963.1 - 6.6e-87 291.3 0.0 8.7e-87 290.9 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EGG12963.1 - 5.3e-21 75.3 0.0 3.7e-20 72.6 0.0 2.5 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Haem_degrading PF03928.14 EGG12964.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.7 1 1 1 2 2 2 0 Haem-degrading TPR_2 PF07719.17 EGG12965.1 - 2e-22 77.4 0.1 0.00023 21.1 1.3 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGG12965.1 - 8.8e-20 69.6 2.6 0.00037 20.2 2.0 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGG12965.1 - 2.8e-14 52.1 4.4 0.36 11.2 0.0 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGG12965.1 - 1.1e-11 44.8 0.5 0.028 14.7 0.1 5.5 5 2 0 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG12965.1 - 2.2e-09 37.4 2.5 3.4e-06 27.2 0.1 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EGG12965.1 - 8.9e-08 31.7 4.9 0.083 12.6 0.0 5.5 3 2 3 6 6 6 2 TPR repeat TPR_19 PF14559.6 EGG12965.1 - 6.9e-07 29.7 0.0 0.0089 16.5 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG12965.1 - 5.9e-06 26.8 0.0 0.46 11.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG12965.1 - 1.3e-05 25.2 0.0 3.3 8.3 0.0 5.8 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG12965.1 - 2e-05 25.0 0.0 1.3 10.0 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG12965.1 - 9.8e-05 22.1 0.0 12 6.2 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG12965.1 - 0.00011 22.6 0.4 13 6.6 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGG12965.1 - 0.016 15.3 0.0 2.8 8.1 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat PknG_TPR PF16918.5 EGG12965.1 - 0.04 12.6 0.0 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat AlgF PF11182.8 EGG12966.1 - 0.015 15.1 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF p450 PF00067.22 EGG12967.1 - 1.1e-68 232.1 0.0 1.4e-68 231.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGG12968.1 - 2.3e-53 181.6 0.0 3.2e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M26_C PF07580.14 EGG12968.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region AMP-binding PF00501.28 EGG12969.1 - 6.7e-57 193.0 0.0 9.7e-55 185.9 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme Alpha_kinase PF02816.18 EGG12971.1 - 5.1e-12 46.3 0.0 7.2e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family ATP12 PF07542.11 EGG12972.1 - 5.3e-42 142.9 0.1 8.7e-42 142.2 0.1 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein DUF3865 PF12981.7 EGG12972.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) LRR_8 PF13855.6 EGG12973.1 - 0.018 14.8 0.1 0.043 13.6 0.1 1.6 2 0 0 2 2 2 0 Leucine rich repeat Galactosyl_T PF01762.21 EGG12974.1 - 0.0058 16.5 0.3 6.6 6.5 0.0 3.1 2 1 1 3 3 3 2 Galactosyltransferase PI3K_1B_p101 PF10486.9 EGG12974.1 - 0.57 7.9 3.8 0.81 7.4 3.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4355 PF14265.6 EGG12976.1 - 0.036 14.3 3.8 0.061 13.6 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) AMP-binding PF00501.28 EGG12978.1 - 2e-80 270.5 0.0 2.5e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG12978.1 - 5.7e-19 68.9 0.1 1.8e-18 67.3 0.2 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Lum_binding PF00677.17 EGG12981.1 - 3e-42 142.5 0.5 3.4e-22 78.2 0.2 2.2 2 0 0 2 2 2 2 Lumazine binding domain AFT PF08731.11 EGG12984.1 - 0.013 15.9 1.6 0.021 15.2 1.6 1.4 1 1 0 1 1 1 0 Transcription factor AFT FAR1 PF03101.15 EGG12984.1 - 0.013 16.2 1.6 0.026 15.2 1.6 1.5 1 1 0 1 1 1 0 FAR1 DNA-binding domain FmiP_Thoc5 PF09766.9 EGG12986.1 - 0.011 15.1 2.2 1.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Allexi_40kDa PF05549.11 EGG12986.1 - 0.078 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein DBP10CT PF08147.12 EGG12988.1 - 0.0092 16.2 1.0 0.074 13.3 0.0 2.8 2 1 0 2 2 2 1 DBP10CT (NUC160) domain Med30 PF11315.8 EGG12988.1 - 0.4 10.9 2.2 0.7 10.1 1.2 1.9 1 1 1 2 2 2 0 Mediator complex subunit 30 F-box-like PF12937.7 EGG12989.1 - 2.6e-05 24.0 0.0 7.7e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 F-box-like DUF2935 PF11155.8 EGG12990.1 - 0.043 14.2 0.1 1.7 9.0 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Alpha_kinase PF02816.18 EGG12991.1 - 1.1e-35 123.5 1.9 1.5e-35 123.0 1.9 1.2 1 0 0 1 1 1 1 Alpha-kinase family PI3K_1B_p101 PF10486.9 EGG12992.1 - 0.36 8.5 24.9 0.55 8.0 24.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SDA1 PF05285.12 EGG12992.1 - 3.6 6.9 34.4 9.9 5.5 34.4 1.8 1 0 0 1 1 1 0 SDA1 GREB1 PF15782.5 EGG12992.1 - 7.1 3.6 15.8 9 3.3 15.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RRN3 PF05327.11 EGG12992.1 - 9.6 4.6 15.5 15 4.0 15.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SGT1 PF07093.11 EGG12994.1 - 6.8e-78 262.6 28.8 6.8e-78 262.6 28.8 3.7 2 1 0 3 3 3 1 SGT1 protein YjeF_N PF03853.15 EGG12996.1 - 1.8e-07 31.2 0.2 4.4e-06 26.7 0.2 2.2 1 1 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EGG12996.1 - 1e-05 26.3 0.1 3.4e-05 24.7 0.1 1.9 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 EGG12996.1 - 0.00053 20.1 0.1 0.0012 18.9 0.1 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EGG12996.1 - 0.051 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Scd6-like Sm domain Ni_hydr_CYTB PF01292.20 EGG12997.1 - 0.012 15.3 0.1 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 SMN PF06003.12 EGG12997.1 - 8.4 5.6 7.9 0.42 9.8 2.0 1.7 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) adh_short PF00106.25 EGG12998.1 - 2e-32 112.2 0.2 4.2e-32 111.2 0.1 1.5 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG12998.1 - 9.3e-24 84.3 0.0 1.3e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG12998.1 - 6e-06 26.3 0.3 1.5e-05 25.0 0.3 1.5 1 1 0 1 1 1 1 KR domain Melibiase_2 PF16499.5 EGG12999.1 - 6e-20 71.6 0.1 1.4e-09 37.5 0.0 3.2 3 0 0 3 3 3 3 Alpha galactosidase A Melibiase_C PF17801.1 EGG12999.1 - 2.6e-08 33.8 0.1 5.2e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EGG12999.1 - 0.00098 18.2 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Melibiase Pex2_Pex12 PF04757.14 EGG13001.1 - 2.3e-42 145.1 6.6 2.8e-42 144.8 6.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EGG13001.1 - 0.00015 21.5 3.7 0.00029 20.6 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG13001.1 - 0.0033 17.2 4.0 0.006 16.4 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HTH_15 PF12324.8 EGG13001.1 - 0.087 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase zf-C3HC4 PF00097.25 EGG13001.1 - 0.18 11.7 2.7 0.33 10.9 2.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGG13001.1 - 0.51 10.5 6.2 1.3 9.2 6.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Septin PF00735.18 EGG13003.1 - 9.7e-106 353.1 0.1 1.7e-105 352.3 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EGG13003.1 - 0.00092 19.3 0.0 0.0022 18.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG13003.1 - 0.031 14.2 1.9 0.18 11.7 0.2 2.7 3 1 0 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 EGG13003.1 - 0.06 13.6 0.5 0.4 10.9 0.0 2.4 3 1 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EGG13003.1 - 0.098 12.0 0.2 0.18 11.1 0.2 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Atg14 PF10186.9 EGG13003.1 - 2.3 7.2 7.6 3.3 6.7 7.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Gelsolin PF00626.22 EGG13004.1 - 5.9e-09 35.7 0.2 8.1e-05 22.4 0.0 2.8 2 0 0 2 2 2 2 Gelsolin repeat ChitinaseA_N PF08329.10 EGG13004.1 - 0.011 15.4 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Chitinase A, N-terminal domain SbcCD_C PF13558.6 EGG13004.1 - 0.33 11.2 1.1 3.5 7.9 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PS_Dcarbxylase PF02666.15 EGG13005.1 - 1.3e-65 220.7 0.0 8e-64 214.9 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Atg14 PF10186.9 EGG13006.1 - 3.7e-07 29.5 10.0 3.7e-07 29.5 10.0 2.7 2 2 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Sec7_N PF12783.7 EGG13006.1 - 0.15 11.9 3.8 0.33 10.8 3.8 1.5 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DoxD PF04173.13 EGG13006.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 TQO small subunit DoxD Y_phosphatase PF00102.27 EGG13007.1 - 9.1e-49 166.1 0.0 1e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGG13007.1 - 7.3e-05 22.6 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGG13007.1 - 0.00029 20.9 0.0 0.00033 20.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EGG13007.1 - 0.014 15.5 0.0 0.069 13.3 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate B12D PF06522.11 EGG13008.1 - 0.039 13.8 0.1 0.059 13.2 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Bee_toxin PF17454.2 EGG13008.1 - 0.082 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Honey bee toxin KDZ PF18758.1 EGG13009.1 - 1.6e-59 201.3 0.1 2.7e-59 200.5 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EGG13009.1 - 1.3e-28 99.2 0.1 3.8e-28 97.7 0.1 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EGG13009.1 - 0.0013 18.9 0.2 0.0029 17.7 0.2 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases SSFA2_C PF14723.6 EGG13009.1 - 0.07 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus EST1 PF10374.9 EGG13009.1 - 0.093 13.4 4.3 0.19 12.3 0.1 3.0 3 0 0 3 3 3 0 Telomerase activating protein Est1 Med2 PF11214.8 EGG13011.1 - 0.0093 16.1 1.9 0.021 15.0 1.9 1.6 1 0 0 1 1 1 1 Mediator complex subunit 2 DUF1003 PF06210.11 EGG13011.1 - 3.7 7.7 4.6 1.1 9.3 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) ArfGap PF01412.18 EGG13012.1 - 3.5e-42 143.2 0.4 5.4e-42 142.6 0.4 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Acetyltransf_10 PF13673.7 EGG13013.1 - 0.00037 20.4 0.0 0.00057 19.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG13013.1 - 0.0012 18.8 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EGG13013.1 - 0.0085 16.3 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG13013.1 - 0.0093 16.4 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 EGG13013.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_72 PF03198.14 EGG13017.1 - 1.4e-88 297.2 0.0 1.9e-88 296.7 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EGG13017.1 - 2.2e-12 47.4 0.2 5.3e-12 46.3 0.2 1.7 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 EGG13017.1 - 0.0019 17.4 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain APC_u15 PF16636.5 EGG13018.1 - 0.61 10.6 5.0 3 8.3 5.0 2.2 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 Skp1 PF01466.19 EGG13018.1 - 0.68 10.1 5.0 7 6.9 0.8 2.7 2 0 0 2 2 2 0 Skp1 family, dimerisation domain GCP_C_terminal PF04130.13 EGG13019.1 - 5.1e-41 141.1 0.2 1.1e-40 140.0 0.2 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGG13019.1 - 1.8e-05 24.6 0.1 0.012 15.2 0.0 2.4 2 0 0 2 2 2 2 Gamma tubulin complex component N-terminal Yae1_N PF09811.9 EGG13020.1 - 3.8 7.3 55.9 1.4 8.6 4.1 10.4 10 0 0 10 10 10 0 Essential protein Yae1, N terminal PUF PF00806.19 EGG13021.1 - 2.8e-23 80.2 0.1 0.00044 19.8 0.0 7.2 7 0 0 7 7 7 6 Pumilio-family RNA binding repeat GATase_4 PF13230.6 EGG13022.1 - 1.5e-18 66.6 0.0 7e-18 64.5 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EGG13022.1 - 3.4e-08 33.8 0.0 6.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain NADH_B2 PF14813.6 EGG13027.1 - 0.00077 19.2 0.3 0.00091 19.0 0.3 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 SNARE_assoc PF09335.11 EGG13028.1 - 1.3e-13 51.5 8.5 1.3e-13 51.5 8.5 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein T2SSM PF04612.12 EGG13028.1 - 0.089 12.8 0.2 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Pkinase PF00069.25 EGG13029.1 - 5.9e-22 78.3 0.0 6.8e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13029.1 - 4.7e-10 39.2 0.0 4.8e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Amidase_5 PF05382.13 EGG13029.1 - 0.00072 19.5 0.1 0.0008 19.3 0.1 1.2 1 0 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase PIP49_C PF12260.8 EGG13029.1 - 0.038 13.6 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kdo PF06293.14 EGG13029.1 - 0.089 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MoaC PF01967.21 EGG13030.1 - 3.6e-45 153.4 0.4 5.6e-45 152.8 0.4 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EGG13030.1 - 8.6e-31 106.5 0.0 2e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EGG13030.1 - 4.2e-24 85.8 0.0 1e-23 84.6 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EGG13030.1 - 3.1e-08 34.0 0.1 1.1e-07 32.2 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EGG13030.1 - 0.0025 17.9 0.3 0.0089 16.2 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain FAD_binding_2 PF00890.24 EGG13031.1 - 6.3e-85 285.8 0.1 9e-85 285.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EGG13031.1 - 5.3e-22 77.8 0.1 1.4e-21 76.4 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EGG13031.1 - 4.9e-14 52.7 0.0 1.1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGG13031.1 - 4.5e-11 42.8 0.3 1.6e-09 37.8 0.1 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG13031.1 - 9.8e-09 34.8 0.2 2.1e-07 30.5 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGG13031.1 - 7.6e-08 32.1 0.4 1.4e-07 31.3 0.4 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG13031.1 - 1.8e-06 26.9 2.4 0.00014 20.7 0.1 3.3 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_3 PF01494.19 EGG13031.1 - 5.9e-06 25.8 0.3 1.3e-05 24.7 0.3 1.5 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EGG13031.1 - 3.5e-05 23.0 0.6 0.0038 16.4 0.3 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGG13031.1 - 3.6e-05 23.2 0.0 0.006 15.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG13031.1 - 5.8e-05 23.6 0.3 0.015 15.8 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGG13031.1 - 0.00011 21.5 1.0 0.0074 15.6 0.4 2.4 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 EGG13031.1 - 0.00031 20.2 0.0 0.0009 18.6 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EGG13031.1 - 0.00036 19.9 0.1 0.00071 18.9 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EGG13031.1 - 0.056 13.4 0.2 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EGG13031.1 - 0.057 12.5 0.1 0.3 10.1 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GDI PF00996.18 EGG13031.1 - 0.085 11.4 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor NAD_binding_7 PF13241.6 EGG13031.1 - 0.11 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding MFS_1 PF07690.16 EGG13033.1 - 3.1e-31 108.6 16.7 7.2e-28 97.5 15.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG13033.1 - 4.8e-10 38.9 3.1 8.2e-10 38.1 3.1 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EGG13033.1 - 3.5e-07 29.0 0.6 5.2e-07 28.5 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EGG13033.1 - 4e-05 22.6 0.0 0.0035 16.3 0.0 3.0 1 1 0 1 1 1 1 MFS_1 like family Cytochrom_B_C PF00032.17 EGG13033.1 - 0.032 14.5 0.0 0.18 12.1 0.0 2.3 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD Phage_Gp19 PF09355.10 EGG13034.1 - 0.022 15.2 0.0 0.037 14.5 0.0 1.3 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 GHMP_kinases_N PF00288.26 EGG13035.1 - 6.1e-08 32.8 2.3 5.7e-07 29.7 1.4 2.6 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGG13035.1 - 5.3e-07 29.9 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Lyase_8_N PF08124.11 EGG13038.1 - 0.022 13.7 0.1 0.23 10.3 0.1 2.0 1 1 1 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Pro_isomerase PF00160.21 EGG13040.1 - 6.1e-42 143.6 0.0 7e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sld7_N PF18636.1 EGG13040.1 - 0.019 15.3 0.0 0.031 14.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain Alpha_kinase PF02816.18 EGG13042.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Alpha-kinase family DUF1925 PF09094.11 EGG13043.1 - 0.013 15.8 1.0 0.043 14.1 0.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1925) PDCD9 PF07147.12 EGG13043.1 - 0.23 10.6 3.1 0.35 10.0 3.1 1.2 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) TPX2 PF06886.11 EGG13043.1 - 4.7 7.5 8.1 0.18 12.0 1.9 1.8 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Avl9 PF09794.9 EGG13046.1 - 2.7e-98 329.1 0.0 2.5e-77 260.2 0.0 3.1 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.9 EGG13046.1 - 3.7e-08 33.3 0.0 0.0013 18.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 EGG13046.1 - 6e-08 32.6 0.1 0.00034 20.5 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.12 EGG13046.1 - 1.2e-05 25.8 0.0 2.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.21 EGG13046.1 - 0.052 13.5 0.1 1.4 8.9 0.1 2.3 2 0 0 2 2 2 0 DENN (AEX-3) domain eIF3_subunit PF08597.10 EGG13047.1 - 3.3e-62 210.5 14.4 3.8e-62 210.4 14.4 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CDC45 PF02724.14 EGG13047.1 - 8 4.6 9.2 9.8 4.3 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein POB3_N PF17292.2 EGG13048.1 - 5.3e-31 106.9 0.1 1.2e-29 102.5 0.0 2.5 2 0 0 2 2 2 1 POB3-like N-terminal PH domain SSrecog PF03531.14 EGG13048.1 - 1.4e-24 85.7 0.9 4.9e-23 80.8 0.0 2.7 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EGG13048.1 - 5e-21 74.9 0.1 6e-20 71.5 0.0 2.6 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF4597 PF15366.6 EGG13049.1 - 0.055 13.2 0.0 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Rhodanese_C PF12368.8 EGG13049.1 - 0.24 11.8 11.2 0.083 13.3 3.6 2.4 1 1 1 2 2 2 0 Rhodanase C-terminal zf-RING_5 PF14634.6 EGG13051.1 - 0.00012 22.0 7.6 0.00019 21.3 7.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGG13051.1 - 0.061 13.5 2.0 0.15 12.3 2.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ADIP PF11559.8 EGG13051.1 - 0.083 13.0 0.7 0.16 12.1 0.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-RING_UBOX PF13445.6 EGG13051.1 - 0.41 10.7 6.9 0.76 9.9 6.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGG13051.1 - 6.7 6.7 6.8 19 5.2 6.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MBOAT_2 PF13813.6 EGG13052.1 - 7.3e-08 32.6 0.9 7.3e-08 32.6 0.9 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family F_bP_aldolase PF01116.20 EGG13053.1 - 2.8e-92 309.1 0.0 3.2e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II LeuA_dimer PF08502.10 EGG13053.1 - 0.093 12.6 0.9 0.18 11.7 0.9 1.4 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain TB2_DP1_HVA22 PF03134.19 EGG13054.1 - 5.6e-25 87.1 6.4 9.3e-25 86.4 6.4 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PXB PF12828.7 EGG13058.1 - 1.8e-07 31.2 0.3 3.5e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 PX-associated CLTH PF10607.9 EGG13060.1 - 1.4e-13 51.0 0.1 2e-12 47.2 0.0 2.4 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGG13060.1 - 0.0041 17.0 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 LisH CENP-C_C PF11699.8 EGG13061.1 - 1.6e-20 73.1 0.1 2.9e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 EGG13061.1 - 6.7e-07 30.1 15.3 0.00013 22.7 7.3 3.5 3 1 0 3 3 3 2 Kinetochore CENP-C fungal homologue, Mif2, N-terminal MTS PF05175.14 EGG13062.1 - 1.7e-08 34.2 0.0 6.5e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 EGG13062.1 - 0.022 14.5 0.0 0.05 13.3 0.0 1.5 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 EGG13062.1 - 0.086 13.6 0.0 0.16 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGG13062.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF2076 PF09849.9 EGG13064.1 - 5.6e-08 33.2 4.1 6e-08 33.0 4.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EGG13064.1 - 8.2e-06 25.8 0.7 1.3e-05 25.1 0.7 1.4 1 0 0 1 1 1 1 CHCH domain Zn-C2H2_12 PF18112.1 EGG13064.1 - 0.79 10.2 2.8 4 8.0 0.5 2.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain tRNA_bind_3 PF17176.4 EGG13065.1 - 0.043 14.1 0.0 0.052 13.8 0.0 1.3 1 1 0 1 1 1 0 tRNA-binding domain CBP_GIL PF10995.8 EGG13066.1 - 0.042 12.5 0.4 0.05 12.3 0.4 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis GIL DUF2694 PF10904.8 EGG13066.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) Inositol_P PF00459.25 EGG13067.1 - 1.2e-46 159.4 0.0 1e-45 156.4 0.0 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family Pollen_allerg_1 PF01357.21 EGG13068.1 - 7.3e-05 22.7 0.2 7.3e-05 22.7 0.2 1.8 2 0 0 2 2 2 1 Pollen allergen Barwin PF00967.17 EGG13068.1 - 0.00064 19.6 0.1 0.0014 18.5 0.0 1.6 2 0 0 2 2 2 1 Barwin family BNR PF02012.20 EGG13068.1 - 0.015 15.2 0.0 0.015 15.2 0.0 2.7 3 0 0 3 3 3 0 BNR/Asp-box repeat DPBB_1 PF03330.18 EGG13068.1 - 0.18 12.1 0.6 3.3 8.0 0.3 2.7 2 1 0 2 2 2 0 Lytic transglycolase DUF2235 PF09994.9 EGG13069.1 - 7.8e-57 192.8 0.0 9.4e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MSC PF09402.10 EGG13070.1 - 1.5e-79 267.9 0.2 3e-79 266.9 0.2 1.5 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EGG13070.1 - 1.1e-05 25.0 0.1 2.9e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 HeH/LEM domain MethyltransfD12 PF02086.15 EGG13070.1 - 0.004 16.9 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Membralin PF09746.9 EGG13070.1 - 7.4 5.5 6.3 13 4.7 6.3 1.3 1 0 0 1 1 1 0 Tumour-associated protein Cpn60_TCP1 PF00118.24 EGG13072.1 - 3.1e-21 75.6 0.1 3.5e-21 75.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4600 PF15372.6 EGG13075.1 - 0.069 13.6 0.1 0.18 12.2 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Alpha_kinase PF02816.18 EGG13078.1 - 7.5e-08 32.7 0.9 1.1e-07 32.2 0.9 1.2 1 0 0 1 1 1 1 Alpha-kinase family GCP_C_terminal PF04130.13 EGG13080.1 - 0.00084 18.9 10.5 0.0018 17.8 10.5 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal NSP2-B_epitope PF14757.6 EGG13080.1 - 0.032 13.9 1.5 0.054 13.2 1.5 1.4 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Pex19 PF04614.12 EGG13080.1 - 0.43 10.3 13.5 1.4 8.7 13.5 2.0 1 1 0 1 1 1 0 Pex19 protein family ANAPC2 PF08672.11 EGG13080.1 - 0.74 10.4 4.1 1.3 9.6 0.8 3.1 2 2 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 PIN_8 PF18476.1 EGG13080.1 - 1.2 9.0 15.0 0.059 13.2 2.5 2.5 1 1 1 2 2 2 0 PIN like domain HEAT PF02985.22 EGG13081.1 - 1.5e-05 24.9 4.7 3.1 8.3 0.0 6.2 5 1 1 6 6 6 2 HEAT repeat Pkinase PF00069.25 EGG13081.1 - 0.0006 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13081.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase OTCace PF00185.24 EGG13082.1 - 0.08 13.0 0.7 0.18 11.8 0.2 1.8 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain RPT PF13446.6 EGG13082.1 - 0.45 10.5 4.7 1.6 8.7 0.2 3.0 3 0 0 3 3 3 0 A repeated domain in UCH-protein Methyltransf_15 PF09445.10 EGG13083.1 - 5.7e-42 143.1 0.1 1e-40 139.0 0.1 2.0 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EGG13083.1 - 4.7e-09 36.8 0.0 7.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG13083.1 - 5.6e-09 36.0 0.0 6.4e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EGG13083.1 - 4.6e-08 33.0 0.1 5.8e-07 29.4 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 EGG13083.1 - 3.7e-07 30.1 0.1 8e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EGG13083.1 - 4.7e-07 29.6 0.0 6.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 EGG13083.1 - 9.9e-06 26.1 0.0 1.6e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG13083.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EGG13083.1 - 0.00035 20.5 0.0 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EGG13083.1 - 0.0013 17.9 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.13 EGG13083.1 - 0.0036 16.7 0.1 0.0053 16.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_5 PF01795.19 EGG13083.1 - 0.0056 16.2 0.0 0.008 15.7 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family TRM PF02005.16 EGG13083.1 - 0.0091 15.2 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase DUF43 PF01861.16 EGG13083.1 - 0.0098 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_24 PF13578.6 EGG13083.1 - 0.037 15.1 0.0 0.066 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 EGG13083.1 - 0.037 13.7 0.1 0.071 12.8 0.1 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) N6_Mtase PF02384.16 EGG13083.1 - 0.043 13.1 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase ADH_zinc_N PF00107.26 EGG13083.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SAM_MT PF04445.13 EGG13083.1 - 0.081 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase tRNA_U5-meth_tr PF05958.11 EGG13083.1 - 0.19 10.7 0.0 0.3 10.0 0.1 1.4 1 1 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Cutinase PF01083.22 EGG13084.1 - 2.9e-22 79.5 1.2 3.6e-22 79.2 1.2 1.1 1 0 0 1 1 1 1 Cutinase CBM_21 PF03370.13 EGG13086.1 - 1.8e-26 92.6 0.1 3.3e-26 91.7 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EGG13086.1 - 2.6e-10 40.7 0.0 6.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) AIRC PF00731.20 EGG13087.1 - 2.4e-61 205.7 1.6 4.7e-61 204.7 1.6 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EGG13087.1 - 2.2e-41 141.3 0.0 3.4e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EGG13087.1 - 8.5e-17 60.6 0.0 1.6e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EGG13087.1 - 0.0019 17.8 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.19 EGG13087.1 - 0.0026 17.1 0.0 0.13 11.6 0.0 2.6 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_D2 PF02786.17 EGG13087.1 - 0.005 16.4 0.0 0.0095 15.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF1297 PF06973.12 EGG13087.1 - 0.03 13.9 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1297) PrpR_N PF06506.11 EGG13087.1 - 0.032 13.8 1.1 0.65 9.6 0.1 2.9 3 1 0 3 3 3 0 Propionate catabolism activator ATP-grasp_3 PF02655.14 EGG13087.1 - 0.046 13.8 0.1 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain Histone PF00125.24 EGG13088.1 - 1.5e-51 174.2 2.6 1.6e-51 174.1 2.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGG13088.1 - 0.00014 22.5 1.2 0.00016 22.2 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EGG13088.1 - 0.00015 22.1 0.0 0.00023 21.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGG13088.1 - 0.00019 21.5 0.5 0.00028 20.9 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EGG13088.1 - 0.002 18.4 0.1 0.0038 17.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGG13088.1 - 0.034 14.2 0.2 0.055 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PRAI PF00697.22 EGG13088.1 - 0.15 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase WD40 PF00400.32 EGG13089.1 - 4.7e-41 138.0 23.1 4.5e-08 33.6 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG13089.1 - 1.2e-15 57.6 0.8 0.00012 22.3 0.1 5.6 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG13089.1 - 2.4e-07 30.8 0.0 0.0017 18.3 0.0 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGG13089.1 - 0.0013 17.8 0.1 0.094 11.7 0.1 2.6 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGG13089.1 - 0.026 13.8 0.0 1.2 8.4 0.0 2.4 1 1 0 2 2 2 0 WD40-like domain adh_short PF00106.25 EGG13090.1 - 1.5e-40 138.8 0.4 2.3e-40 138.2 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG13090.1 - 2.9e-37 128.4 0.1 5.9e-37 127.5 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG13090.1 - 2.6e-10 40.5 2.7 7.4e-10 39.0 2.7 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG13090.1 - 0.0021 17.6 0.3 0.0044 16.5 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 EGG13090.1 - 0.0022 18.5 0.3 0.0058 17.2 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_tran_WecB PF03808.13 EGG13090.1 - 0.003 17.5 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family GDP_Man_Dehyd PF16363.5 EGG13090.1 - 0.0082 15.6 0.4 0.022 14.2 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Pyr_redox_2 PF07992.14 EGG13090.1 - 0.012 14.8 0.1 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.15 EGG13090.1 - 0.016 14.4 0.3 0.027 13.6 0.3 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 EGG13090.1 - 0.024 14.5 0.4 0.044 13.7 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EGG13090.1 - 0.045 12.4 0.6 0.92 8.1 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein AdoHcyase_NAD PF00670.21 EGG13090.1 - 0.088 12.9 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain adh_short PF00106.25 EGG13091.1 - 4.8e-39 133.8 0.1 6.2e-39 133.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG13091.1 - 2.6e-32 112.3 0.0 4.4e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG13091.1 - 1.5e-08 34.7 1.1 3.9e-08 33.4 0.3 1.9 2 1 0 2 2 2 1 KR domain Glyco_tran_WecB PF03808.13 EGG13091.1 - 0.001 19.0 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family Pyr_redox PF00070.27 EGG13091.1 - 0.033 14.7 0.8 0.11 13.1 0.4 2.0 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 EGG13091.1 - 0.034 13.6 0.3 0.14 11.6 0.1 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG13091.1 - 0.052 13.0 0.5 0.12 11.8 0.5 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EGG13091.1 - 0.32 10.9 1.9 0.28 11.0 0.7 1.6 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CENP-T_C PF15511.6 EGG13092.1 - 4.8e-08 33.1 0.1 5.9e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EGG13092.1 - 8.4e-05 22.7 0.1 0.00012 22.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGG13092.1 - 0.00018 21.9 0.0 0.00023 21.5 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EGG13092.1 - 0.0011 19.4 0.1 0.0012 19.2 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGG13092.1 - 0.0015 18.7 0.1 0.0029 17.8 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGG13092.1 - 0.073 13.2 0.0 0.082 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_L27A PF00828.19 EGG13092.1 - 0.45 11.2 4.0 0.57 10.9 4.0 1.3 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ELMO_CED12 PF04727.13 EGG13093.1 - 7.8e-24 84.7 0.0 1.6e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Maf1 PF09174.10 EGG13096.1 - 0.25 11.5 0.1 0.25 11.5 0.1 1.7 2 1 0 2 2 2 0 Maf1 regulator YfhO PF09586.10 EGG13096.1 - 0.34 9.1 0.8 0.44 8.7 0.8 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF469 PF04320.14 EGG13097.1 - 0.065 14.1 0.0 0.3 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein with unknown function (DUF469) Vps54 PF07928.12 EGG13101.1 - 4e-52 176.2 2.6 4e-52 176.2 2.6 2.9 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 EGG13101.1 - 6.2e-05 22.4 0.2 6.2e-05 22.4 0.2 2.9 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex zf-RING_2 PF13639.6 EGG13103.1 - 5.9e-08 32.9 5.2 9.3e-08 32.3 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGG13103.1 - 2.2e-05 24.3 3.7 4.3e-05 23.4 3.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGG13103.1 - 0.00028 20.5 3.2 0.00028 20.5 3.2 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGG13103.1 - 0.0018 18.3 2.5 0.0018 18.3 2.5 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGG13103.1 - 0.021 14.7 2.9 0.041 13.8 2.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FucT_N PF18025.1 EGG13103.1 - 0.026 14.9 0.0 0.05 14.1 0.0 1.5 1 0 0 1 1 1 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain Prok-RING_4 PF14447.6 EGG13103.1 - 0.034 14.0 5.6 0.66 9.9 1.1 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGG13103.1 - 0.044 13.6 5.7 0.082 12.8 5.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG13103.1 - 0.05 13.5 1.8 0.13 12.2 1.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGG13103.1 - 0.11 12.5 0.4 5.6 7.1 0.2 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger STAG PF08514.11 EGG13104.1 - 2.5e-09 37.0 0.7 6.3e-09 35.7 0.7 1.7 1 0 0 1 1 1 1 STAG domain TPR_MLP1_2 PF07926.12 EGG13104.1 - 0.0099 15.9 0.2 0.027 14.5 0.2 1.7 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF4119 PF13494.6 EGG13104.1 - 0.031 14.4 0.3 0.031 14.4 0.3 2.5 3 1 1 4 4 4 0 Domain of unknown function, B. Theta Gene description (DUF4119) RasGEF_N PF00618.20 EGG13104.1 - 0.071 13.4 0.4 0.071 13.4 0.4 2.4 2 1 0 2 2 2 0 RasGEF N-terminal motif HEAT PF02985.22 EGG13104.1 - 0.091 13.1 0.0 0.35 11.2 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat KorB_C PF06613.11 EGG13105.1 - 0.21 11.6 1.0 0.57 10.2 0.0 2.3 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain BNIP2 PF12496.8 EGG13106.1 - 3.5 8.1 7.5 0.46 10.9 2.7 2.0 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PdaC PF13739.6 EGG13108.1 - 0.0076 17.2 0.1 0.023 15.7 0.1 1.9 1 0 0 1 1 1 1 Deacetylase PdaC VPS28 PF03997.12 EGG13109.1 - 0.09 12.4 0.2 3.2 7.4 0.1 2.4 2 0 0 2 2 2 0 VPS28 protein DUF445 PF04286.12 EGG13109.1 - 0.14 12.0 1.0 0.24 11.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF445) MAGE PF01454.19 EGG13111.1 - 1.6e-33 116.2 0.0 2.1e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 MAGE family MatE PF01554.18 EGG13112.1 - 5.1e-48 162.8 28.3 3.8e-26 91.7 4.8 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EGG13112.1 - 6.5e-07 29.5 15.7 6.5e-07 29.5 15.7 3.7 3 2 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain GDA1_CD39 PF01150.17 EGG13113.1 - 2.2e-97 326.4 0.0 3.1e-97 325.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family vATP-synt_AC39 PF01992.16 EGG13115.1 - 4.8e-117 391.2 0.2 5.4e-117 391.1 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit GMC_oxred_N PF00732.19 EGG13116.1 - 7.8e-37 127.2 0.0 1.1e-36 126.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGG13116.1 - 2.3e-30 106.0 0.0 4.2e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGG13116.1 - 0.28 10.2 0.8 1 8.4 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain DEAD PF00270.29 EGG13117.1 - 4.2e-41 140.6 0.0 5.2e-40 137.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG13117.1 - 3.1e-24 85.4 0.0 1.5e-23 83.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EGG13117.1 - 9.7e-19 67.4 2.0 9.7e-19 67.4 2.0 2.8 3 0 0 3 3 3 1 DBP10CT (NUC160) domain ResIII PF04851.15 EGG13117.1 - 0.00017 21.6 0.0 0.00088 19.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ste5 PF11610.8 EGG13117.1 - 0.13 12.2 0.1 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 Scaffold protein Ste5, Fus3-binding region Med13_C PF06333.12 EGG13117.1 - 2.1 7.5 4.0 15 4.7 0.5 2.2 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Voltage_CLC PF00654.20 EGG13118.1 - 2e-90 303.6 18.2 2e-90 303.6 18.2 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGG13118.1 - 0.02 15.3 0.1 0.54 10.7 0.0 2.5 2 0 0 2 2 2 0 CBS domain Njmu-R1 PF15053.6 EGG13120.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Mjmu-R1-like protein family DUF1241 PF06840.11 EGG13120.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Cellulase PF00150.18 EGG13121.1 - 2e-11 43.8 0.0 3.1e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pribosyltran PF00156.27 EGG13122.1 - 0.00017 21.1 0.1 0.00074 19.1 0.1 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PIGA PF08288.12 EGG13123.1 - 8.1e-32 109.7 0.2 2.1e-31 108.3 0.2 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 EGG13123.1 - 1.9e-24 86.1 0.0 3.2e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGG13123.1 - 1.8e-23 83.4 0.5 3.9e-23 82.3 0.3 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EGG13123.1 - 4.3e-23 82.2 0.1 7.5e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGG13123.1 - 2.3e-12 47.7 0.0 3.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGG13123.1 - 8.3e-05 22.9 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EGG13123.1 - 0.00074 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_28 PF03033.20 EGG13123.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Glyco_transf_5 PF08323.11 EGG13123.1 - 0.1 12.3 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 Starch synthase catalytic domain EF-hand_13 PF17958.1 EGG13124.1 - 0.063 13.1 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Pribosyltran PF00156.27 EGG13125.1 - 0.00035 20.1 0.2 0.0029 17.2 0.1 2.2 2 1 0 2 2 2 1 Phosphoribosyl transferase domain PIGA PF08288.12 EGG13126.1 - 5.4e-32 110.2 0.2 1.4e-31 108.9 0.2 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 EGG13126.1 - 1.9e-24 86.1 0.0 3.2e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGG13126.1 - 1.4e-23 83.7 0.6 3e-23 82.7 0.3 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EGG13126.1 - 4.3e-23 82.2 0.1 7.5e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGG13126.1 - 1.5e-12 48.3 0.0 2.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGG13126.1 - 8.3e-05 22.9 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EGG13126.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 EGG13126.1 - 0.1 12.2 0.1 1.1 8.9 0.1 2.1 1 1 0 1 1 1 0 Starch synthase catalytic domain Sugar_tr PF00083.24 EGG13128.1 - 1.8e-99 333.7 24.8 2.1e-99 333.5 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG13128.1 - 1.1e-23 83.8 59.0 1e-21 77.3 31.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Helicase_C PF00271.31 EGG13129.1 - 3.8e-21 75.5 0.0 4.4e-18 65.6 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG13129.1 - 1.3e-17 64.1 0.0 2.6e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EGG13129.1 - 2.7e-12 47.2 3.5 8.2e-12 45.7 3.5 1.9 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 EGG13129.1 - 9e-08 31.9 0.0 4e-07 29.8 0.1 2.1 2 0 0 2 2 2 1 RQC domain ResIII PF04851.15 EGG13129.1 - 0.0035 17.4 0.0 0.0091 16.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Med18 PF09637.10 EGG13130.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 Med18 protein SCO1-SenC PF02630.14 EGG13132.1 - 0.18 11.7 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC FAD_binding_4 PF01565.23 EGG13133.1 - 2.9e-21 75.7 1.7 6.3e-21 74.6 0.6 2.0 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 EGG13133.1 - 1.3e-07 31.6 0.0 2.7e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.19 EGG13133.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain WD40 PF00400.32 EGG13134.1 - 2.8e-18 65.9 10.9 0.0015 19.3 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG13134.1 - 1e-08 35.3 1.3 0.57 10.5 0.0 5.2 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG13134.1 - 0.11 11.4 0.0 14 4.6 0.0 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BaxI_1 PF12811.7 EGG13135.1 - 0.068 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF2205 PF10224.9 EGG13136.1 - 1.5e-11 44.2 0.5 1.6e-11 44.0 0.5 1.1 1 0 0 1 1 1 1 Short coiled-coil protein TACC_C PF05010.14 EGG13136.1 - 0.00054 19.8 0.7 0.00055 19.8 0.7 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal KASH_CCD PF14662.6 EGG13136.1 - 0.0022 17.8 2.0 0.0028 17.5 2.0 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 EGG13136.1 - 0.0026 17.8 0.3 0.0026 17.8 0.3 1.0 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.6 EGG13136.1 - 0.0036 17.3 1.0 0.0046 16.9 1.0 1.1 1 0 0 1 1 1 1 FlxA-like protein Tropomyosin_1 PF12718.7 EGG13136.1 - 0.0058 16.8 0.7 0.0063 16.7 0.7 1.1 1 0 0 1 1 1 1 Tropomyosin like DivIC PF04977.15 EGG13136.1 - 0.006 16.3 2.1 0.01 15.6 0.8 1.8 1 1 1 2 2 2 2 Septum formation initiator bZIP_2 PF07716.15 EGG13136.1 - 0.006 16.6 1.9 0.069 13.2 0.1 2.2 2 0 0 2 2 2 1 Basic region leucine zipper CENP-H PF05837.12 EGG13136.1 - 0.009 16.4 1.1 0.01 16.2 1.1 1.1 1 0 0 1 1 1 1 Centromere protein H (CENP-H) Dor1 PF04124.12 EGG13136.1 - 0.0095 14.7 0.7 0.01 14.5 0.7 1.0 1 0 0 1 1 1 1 Dor1-like family HALZ PF02183.18 EGG13136.1 - 0.011 15.9 1.7 0.37 11.1 0.3 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 EGG13136.1 - 0.02 15.0 1.6 0.85 9.8 0.2 2.1 1 1 1 2 2 2 0 bZIP transcription factor Sec34 PF04136.15 EGG13136.1 - 0.023 14.6 0.5 0.026 14.4 0.5 1.1 1 0 0 1 1 1 0 Sec34-like family AKNA PF12443.8 EGG13136.1 - 0.025 15.2 0.3 0.026 15.1 0.3 1.2 1 0 0 1 1 1 0 AT-hook-containing transcription factor ZapB PF06005.12 EGG13136.1 - 0.034 14.6 1.9 0.049 14.1 1.9 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DUF1664 PF07889.12 EGG13136.1 - 0.037 14.1 0.2 0.045 13.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 EGG13136.1 - 0.037 14.1 1.8 0.15 12.1 1.7 1.9 1 1 0 1 1 1 0 TolA binding protein trimerisation DUF641 PF04859.12 EGG13136.1 - 0.048 14.0 0.3 0.054 13.8 0.3 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Syntaxin-6_N PF09177.11 EGG13136.1 - 0.05 14.2 0.5 0.057 14.0 0.5 1.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal CLZ PF16526.5 EGG13136.1 - 0.058 13.8 0.5 0.15 12.5 0.4 1.7 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YabA PF06156.13 EGG13136.1 - 0.082 13.6 1.2 0.095 13.4 1.2 1.1 1 0 0 1 1 1 0 Initiation control protein YabA Qua1 PF16274.5 EGG13136.1 - 0.085 12.7 0.2 0.23 11.3 0.2 1.7 1 1 0 1 1 1 0 Qua1 domain IFT20 PF14931.6 EGG13137.1 - 0.023 14.9 0.6 0.066 13.4 0.6 1.7 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 RhoGAP PF00620.27 EGG13139.1 - 3.3e-32 111.4 0.0 6.3e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 EGG13139.1 - 2e-17 63.6 0.2 6e-16 58.9 0.1 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Ribonuc_red_lgC PF02867.15 EGG13141.1 - 5.7e-183 609.2 0.0 2.1e-182 607.3 0.0 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGG13141.1 - 4.8e-24 84.2 0.1 1.1e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGG13141.1 - 1.6e-17 63.9 0.1 4e-17 62.6 0.1 1.8 1 0 0 1 1 1 1 ATP cone domain PPR_2 PF13041.6 EGG13142.1 - 0.00096 19.3 0.1 0.03 14.5 0.0 3.1 4 0 0 4 4 4 1 PPR repeat family SDH_beta PF03315.15 EGG13142.1 - 0.016 15.6 0.1 0.054 13.9 0.1 1.8 1 1 0 1 1 1 0 Serine dehydratase beta chain SDH_alpha PF03313.15 EGG13143.1 - 4.5e-102 341.2 0.6 5.6e-102 340.9 0.6 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 EGG13143.1 - 3.2e-53 180.3 0.0 5.9e-53 179.4 0.0 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain UL40 PF10682.9 EGG13144.1 - 0.01 15.6 0.2 0.012 15.3 0.2 1.1 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 DUF5039 PF16442.5 EGG13144.1 - 0.1 12.1 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) DUF1077 PF06417.12 EGG13145.1 - 1.6e-43 147.5 2.4 2.1e-43 147.1 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) OMP_b-brl_3 PF14905.6 EGG13145.1 - 0.11 11.4 5.2 0.14 11.1 5.2 1.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family SAM_decarbox PF01536.16 EGG13146.1 - 1.3e-120 402.6 0.0 1.7e-120 402.3 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase CFEM PF05730.11 EGG13147.1 - 2.6e-09 37.0 14.9 3.7e-09 36.5 14.9 1.2 1 0 0 1 1 1 1 CFEM domain WD40 PF00400.32 EGG13148.1 - 6.9e-25 86.8 0.2 1.2e-06 29.1 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG13148.1 - 1.1e-11 44.9 0.2 0.0091 16.3 0.2 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG13148.1 - 0.0096 15.3 0.0 4.6 6.5 0.0 3.7 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 EGG13148.1 - 0.012 14.3 1.3 0.11 11.1 0.2 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGG13148.1 - 0.1 11.4 0.7 7.4 5.2 0.0 2.5 2 1 1 3 3 3 0 Nup133 N terminal like YTH PF04146.15 EGG13149.1 - 5.7e-52 176.0 0.0 1.9e-51 174.3 0.0 1.9 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 EGG13149.1 - 7.9e-07 28.8 0.0 2.5e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 EGG13151.1 - 1.8e-75 249.0 0.3 1.5e-25 88.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pro_isomerase PF00160.21 EGG13152.1 - 3.3e-42 144.4 0.0 4.7e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-MYND PF01753.18 EGG13153.1 - 0.09 12.9 5.6 0.25 11.5 5.6 1.8 1 0 0 1 1 1 0 MYND finger zf-HIT PF04438.16 EGG13153.1 - 0.81 9.6 9.3 1.8 8.5 9.3 1.6 1 0 0 1 1 1 0 HIT zinc finger DUF3052 PF11253.8 EGG13154.1 - 0.03 14.2 0.5 0.044 13.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) SWI-SNF_Ssr4 PF08549.10 EGG13156.1 - 0.0032 16.2 8.4 0.0032 16.2 8.4 2.9 1 1 1 3 3 3 2 Fungal domain of unknown function (DUF1750) tRNA_NucTransf2 PF09249.11 EGG13156.1 - 0.14 12.4 0.1 0.34 11.2 0.1 1.6 1 1 0 1 1 1 0 tRNA nucleotidyltransferase, second domain TFIIA PF03153.13 EGG13156.1 - 1.2 9.0 36.0 1.5 8.8 36.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RCC1 PF00415.18 EGG13159.1 - 4.9e-28 97.5 7.5 2.3e-11 44.1 0.1 3.8 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG13159.1 - 1e-16 60.3 14.7 3.4e-11 42.6 0.7 4.2 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat PP1_bind PF15276.6 EGG13160.1 - 0.075 13.4 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein phosphatase 1 binding Med22 PF06179.12 EGG13161.1 - 4.8e-15 55.6 2.2 8.6e-15 54.8 2.2 1.4 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Mad3_BUB1_I PF08311.12 EGG13162.1 - 1.7e-33 115.3 0.4 2.7e-33 114.6 0.4 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 EGG13162.1 - 1.3e-06 28.5 0.1 2.5e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Cellulase PF00150.18 EGG13163.1 - 4.8e-14 52.4 0.0 7.5e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DCB PF16213.5 EGG13164.1 - 3.9e-59 199.3 0.5 1.4e-58 197.5 0.5 2.0 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EGG13164.1 - 6.4e-51 172.4 3.7 9.2e-51 171.9 0.9 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 EGG13164.1 - 1.1e-29 103.2 5.5 1.4e-24 86.3 0.7 4.1 2 1 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 EGG13164.1 - 0.11 12.3 0.0 4.3 7.3 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) HEAT PF02985.22 EGG13164.1 - 0.14 12.5 0.8 2e+02 2.6 0.2 4.9 4 0 0 4 4 4 0 HEAT repeat DUF4336 PF14234.6 EGG13165.1 - 1.9e-12 47.0 0.1 4e-06 26.3 0.0 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Lactamase_B_5 PF14597.6 EGG13165.1 - 0.056 12.9 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DHHC PF01529.20 EGG13166.1 - 1.3e-35 122.4 4.2 1.3e-35 122.4 4.2 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase PIG-Y PF15159.6 EGG13166.1 - 3.6 8.6 6.8 16 6.5 3.7 2.7 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Pkinase PF00069.25 EGG13167.1 - 1.4e-75 254.0 0.0 1.6e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13167.1 - 4.8e-43 147.3 0.0 5.7e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG13167.1 - 8e-09 35.2 0.0 1.3e-08 34.5 0.0 1.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGG13167.1 - 0.00034 20.0 0.0 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG13167.1 - 0.024 14.6 0.4 0.4 10.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG13167.1 - 0.033 13.1 0.1 0.041 12.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain AAA PF00004.29 EGG13171.1 - 9.8e-97 320.5 0.0 4e-47 160.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG13171.1 - 2.7e-24 84.7 5.8 1.9e-11 43.6 0.1 3.0 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 EGG13171.1 - 1.8e-19 69.7 0.4 5e-19 68.3 0.4 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EGG13171.1 - 7.1e-14 51.9 0.0 1.7e-05 24.6 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGG13171.1 - 1.7e-13 51.1 0.0 1.4e-07 31.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGG13171.1 - 1.3e-11 44.8 0.0 1.1e-05 25.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EGG13171.1 - 1.1e-10 41.7 0.4 8.6e-05 22.6 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGG13171.1 - 1.9e-10 41.4 0.2 0.00077 19.9 0.0 4.5 3 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EGG13171.1 - 3.9e-09 36.9 0.1 0.045 14.0 0.0 4.2 3 2 0 3 3 2 2 AAA domain TIP49 PF06068.13 EGG13171.1 - 5.3e-09 35.7 0.0 0.0018 17.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 EGG13171.1 - 5.8e-09 35.6 0.0 1.3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Vps4_C PF09336.10 EGG13171.1 - 2e-07 30.9 0.1 9.4e-06 25.5 0.0 3.0 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 EGG13171.1 - 3.9e-07 29.7 0.3 0.026 13.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGG13171.1 - 4.6e-07 29.7 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 EGG13171.1 - 5.2e-07 30.3 0.0 0.02 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGG13171.1 - 1.2e-06 28.8 0.0 0.019 15.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase ATPase PF06745.13 EGG13171.1 - 2.7e-06 26.9 0.2 0.79 9.0 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_14 PF13173.6 EGG13171.1 - 3.2e-06 27.2 0.0 0.029 14.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 EGG13171.1 - 4.7e-06 26.2 0.0 0.019 14.5 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EGG13171.1 - 9.9e-06 24.8 0.1 0.0098 15.0 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 EGG13171.1 - 1.3e-05 25.5 0.1 0.14 12.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 EGG13171.1 - 1.9e-05 24.0 0.0 0.0047 16.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EGG13171.1 - 2.4e-05 24.9 0.0 0.13 12.8 0.0 3.5 2 1 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 EGG13171.1 - 2.5e-05 24.0 0.0 0.34 10.6 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 EGG13171.1 - 3.5e-05 23.5 3.0 0.91 9.1 0.1 3.7 2 2 2 4 4 4 2 AAA domain Bac_DnaA PF00308.18 EGG13171.1 - 5.4e-05 23.1 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_24 PF13479.6 EGG13171.1 - 5.8e-05 22.9 0.1 0.48 10.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain PhoH PF02562.16 EGG13171.1 - 0.00011 21.8 0.2 0.46 9.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 EGG13171.1 - 0.00022 21.3 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 EGG13171.1 - 0.00025 21.1 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EGG13171.1 - 0.00025 21.5 0.0 1 9.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_3 PF07726.11 EGG13171.1 - 0.00032 20.6 0.0 0.93 9.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EGG13171.1 - 0.00087 19.1 0.5 1.3 8.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EGG13171.1 - 0.0026 17.5 0.4 2.1 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGG13171.1 - 0.0027 17.0 0.0 2.4 7.4 0.0 2.9 3 0 0 3 3 2 1 Zeta toxin ATPase_2 PF01637.18 EGG13171.1 - 0.0032 17.4 0.1 4.4 7.1 0.0 3.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 EGG13171.1 - 0.0034 16.7 2.5 0.48 9.6 0.0 2.7 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EGG13171.1 - 0.0035 17.1 0.0 0.28 10.9 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EGG13171.1 - 0.0042 17.4 1.4 3.6 7.9 0.0 3.5 3 1 1 4 4 3 1 AAA domain NACHT PF05729.12 EGG13171.1 - 0.0043 17.0 0.2 1.1 9.1 0.0 3.1 3 0 0 3 3 3 1 NACHT domain Sigma54_activ_2 PF14532.6 EGG13171.1 - 0.0078 16.3 0.0 5.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 EGG13171.1 - 0.0097 15.1 0.0 0.53 9.4 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain T2SSE PF00437.20 EGG13171.1 - 0.012 14.7 0.0 0.42 9.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.15 EGG13171.1 - 0.014 15.4 2.1 3.7 7.4 0.0 4.1 4 0 0 4 4 4 0 NTPase IPT PF01745.16 EGG13171.1 - 0.045 13.1 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UFD1 PF03152.14 EGG13171.1 - 0.049 13.1 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin PF02224.18 EGG13171.1 - 0.05 13.3 0.0 8.2 6.1 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 EGG13171.1 - 0.18 11.4 0.0 6.8 6.3 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Hydin_ADK PF17213.3 EGG13171.1 - 0.29 11.4 1.7 80 3.4 0.0 3.7 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Aldolase_II PF00596.21 EGG13172.1 - 5.6e-46 156.8 0.0 7.1e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TPR_MLP1_2 PF07926.12 EGG13173.1 - 9.2e-29 100.1 17.1 9.2e-29 100.1 17.1 17.6 8 7 6 16 16 16 4 TPR/MLP1/MLP2-like protein RE_Eco29kI PF09517.10 EGG13173.1 - 0.056 13.1 0.2 0.38 10.4 0.2 2.5 1 0 0 1 1 1 0 Eco29kI restriction endonuclease DapH_N PF08503.10 EGG13173.1 - 1.6 9.0 4.5 56 4.1 0.0 4.3 4 0 0 4 4 4 0 Tetrahydrodipicolinate succinyltransferase N-terminal Romo1 PF10247.9 EGG13174.1 - 4.3e-24 84.7 13.1 6.7e-24 84.0 13.1 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 EGG13174.1 - 0.0057 17.0 1.7 0.0072 16.7 1.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RibD_C PF01872.17 EGG13175.1 - 1.4e-11 44.6 0.1 7.7e-05 22.6 0.0 2.1 1 1 1 2 2 2 2 RibD C-terminal domain DUF4214 PF13946.6 EGG13175.1 - 0.017 15.2 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) zf-RING_2 PF13639.6 EGG13178.1 - 7.5e-09 35.8 6.7 1.4e-08 34.9 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGG13178.1 - 2.2e-05 24.3 4.3 3.4e-05 23.7 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGG13178.1 - 7.5e-05 22.4 5.2 0.00019 21.1 1.9 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGG13178.1 - 0.0057 16.5 5.5 0.01 15.7 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG13178.1 - 0.0078 16.0 3.1 0.015 15.1 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG13178.1 - 0.0093 15.8 5.4 0.02 14.7 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG13178.1 - 0.015 15.3 4.4 0.027 14.5 4.4 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 EGG13178.1 - 0.028 14.2 4.7 0.047 13.5 4.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf_C2H2_10 PF18414.1 EGG13178.1 - 0.39 10.3 6.4 0.09 12.3 1.8 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger Prok-RING_4 PF14447.6 EGG13178.1 - 0.84 9.6 7.6 3.1 7.7 0.2 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 EGG13178.1 - 1.6 9.1 5.3 3.7 7.9 5.1 1.7 1 1 0 1 1 1 0 RING-like domain AICARFT_IMPCHas PF01808.18 EGG13179.1 - 2.3e-86 289.9 0.0 3.2e-86 289.4 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EGG13179.1 - 2.3e-20 72.6 0.0 4.2e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Sds3 PF08598.11 EGG13180.1 - 0.44 10.5 14.0 0.06 13.3 8.0 2.5 2 0 0 2 2 2 0 Sds3-like Suv3_C_1 PF18147.1 EGG13181.1 - 4.2e-14 52.1 0.0 8.8e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 SUV3_C PF12513.8 EGG13181.1 - 5.8e-14 51.8 0.3 1.6e-13 50.4 0.3 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EGG13181.1 - 3.3e-09 37.1 0.0 7.2e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGG13181.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain RF-1 PF00472.20 EGG13182.1 - 7.9e-18 64.5 1.7 9.3e-18 64.3 1.7 1.1 1 0 0 1 1 1 1 RF-1 domain His_Phos_1 PF00300.22 EGG13183.1 - 4.3e-28 98.3 0.0 5.5e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) WD40 PF00400.32 EGG13184.1 - 6e-08 33.2 5.3 0.055 14.4 0.2 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.11 EGG13184.1 - 0.0082 16.0 0.0 0.45 10.4 0.0 3.0 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EGG13184.1 - 0.012 15.9 0.0 0.13 12.6 0.0 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG13184.1 - 0.087 11.8 0.0 1.2 8.0 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MBOAT_2 PF13813.6 EGG13186.1 - 1.6e-12 47.5 1.8 2e-12 47.2 1.0 1.6 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family DPM2 PF07297.12 EGG13186.1 - 0.91 9.9 5.6 2.2 8.7 0.6 2.5 1 1 1 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) GMC_oxred_N PF00732.19 EGG13187.1 - 1.8e-62 211.4 0.0 2.3e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGG13187.1 - 5.6e-37 127.5 0.0 9.5e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGG13187.1 - 5.2e-06 25.8 0.1 0.0014 17.8 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EGG13187.1 - 2.9e-05 23.5 0.2 0.022 14.0 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG13187.1 - 4.3e-05 23.6 0.2 0.00042 20.5 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG13187.1 - 8.2e-05 22.0 0.0 0.0006 19.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGG13187.1 - 0.00025 20.2 0.5 0.00046 19.4 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 EGG13187.1 - 0.0013 17.5 0.4 0.022 13.5 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 EGG13187.1 - 0.0018 17.9 0.2 0.009 15.6 0.1 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGG13187.1 - 0.002 17.4 0.1 0.0073 15.6 0.1 1.8 2 0 0 2 2 2 1 Thi4 family GMC_oxred_N PF00732.19 EGG13189.1 - 9e-58 196.0 0.0 1.3e-57 195.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGG13189.1 - 7.3e-37 127.1 0.2 1.3e-36 126.3 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGG13189.1 - 1.1e-05 24.7 1.1 0.00094 18.4 1.3 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EGG13189.1 - 0.00032 19.9 0.2 0.00072 18.7 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 EGG13189.1 - 0.00049 19.4 0.1 0.00089 18.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EGG13189.1 - 0.00057 20.1 0.4 0.0016 18.6 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG13189.1 - 0.0027 17.4 1.2 0.0051 16.4 1.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGG13189.1 - 0.039 13.2 1.7 0.27 10.5 1.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGG13189.1 - 0.044 12.5 0.2 0.079 11.7 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 EGG13189.1 - 0.058 12.6 0.6 0.11 11.7 0.4 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Inhibitor_Mig-6 PF11555.8 EGG13189.1 - 0.33 11.1 0.0 0.33 11.1 0.0 2.1 2 0 0 2 2 1 0 EGFR receptor inhibitor Mig-6 zf-MYND PF01753.18 EGG13190.1 - 6.4e-07 29.3 15.0 1.2e-06 28.5 15.0 1.4 1 0 0 1 1 1 1 MYND finger Bys1 PF04681.12 EGG13190.1 - 0.017 15.1 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Blastomyces yeast-phase-specific protein Peptidase_M50B PF13398.6 EGG13192.1 - 2.5e-28 99.1 12.6 2.5e-28 99.1 12.6 2.2 2 0 0 2 2 2 1 Peptidase M50B-like PH_6 PF15406.6 EGG13194.1 - 0.036 14.3 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain DnaJ PF00226.31 EGG13195.1 - 3.4e-10 39.9 0.1 1.1e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain F-box-like PF12937.7 EGG13196.1 - 0.00021 21.1 0.1 0.00051 19.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG13196.1 - 0.0043 16.9 0.1 0.022 14.6 0.1 2.2 1 1 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGG13196.1 - 0.31 10.9 1.9 0.47 10.3 0.1 2.2 3 0 0 3 3 3 0 F-box DUF1242 PF06842.12 EGG13197.1 - 3.1e-19 68.5 2.4 4.6e-19 67.9 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) BBP2 PF07642.11 EGG13199.1 - 0.039 13.1 0.1 0.069 12.3 0.1 1.3 1 0 0 1 1 1 0 Putative beta-barrel porin-2, OmpL-like. bbp2 IKKbetaNEMObind PF12179.8 EGG13200.1 - 1.5 8.9 4.3 19 5.4 1.4 3.1 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain ARL6IP6 PF15062.6 EGG13201.1 - 2.9 8.1 5.5 29 4.9 0.4 2.7 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Tom22 PF04281.13 EGG13203.1 - 9.7e-37 125.8 0.5 1e-36 125.7 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CxC1 PF18802.1 EGG13205.1 - 3.9e-11 43.0 0.2 8.5e-11 41.9 0.2 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EGG13206.1 - 1.7e-23 83.4 0.0 2.1e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF2387 PF09526.10 EGG13206.1 - 0.1 12.8 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) RE_EcoO109I PF14511.6 EGG13209.1 - 0.021 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I Vps53_N PF04100.12 EGG13211.1 - 6.3e-72 242.6 0.0 1.3e-71 241.6 0.0 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Colicin PF01024.19 EGG13211.1 - 0.06 13.2 0.0 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Colicin pore forming domain TPR_2 PF07719.17 EGG13212.1 - 0.0054 16.7 3.4 3.3 8.1 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG13212.1 - 0.041 14.2 0.5 12 6.2 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGG13212.1 - 0.086 12.7 0.3 13 5.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HHH PF00633.23 EGG13212.1 - 0.82 9.7 2.5 39 4.4 0.2 3.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif TPR_8 PF13181.6 EGG13212.1 - 4.1 7.9 9.8 25 5.4 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1640 PF07798.11 EGG13214.1 - 6.8e-14 52.3 0.1 8e-14 52.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DASH_Duo1 PF08651.10 EGG13214.1 - 0.084 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 Anillin_N PF16018.5 EGG13215.1 - 0.018 15.6 4.6 0.018 15.6 4.6 2.1 2 0 0 2 2 2 0 Anillin N-terminus PH PF00169.29 EGG13215.1 - 0.023 15.2 0.1 0.24 11.9 0.0 2.4 2 0 0 2 2 2 0 PH domain Peptidase_M3_N PF08439.10 EGG13217.1 - 0.047 14.0 1.8 0.12 12.7 0.7 2.3 2 0 0 2 2 2 0 Oligopeptidase F GDP_Man_Dehyd PF16363.5 EGG13219.1 - 6.9e-44 150.6 0.1 7.2e-31 107.8 0.0 2.3 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG13219.1 - 8e-43 146.6 0.1 2.2e-30 105.9 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGG13219.1 - 1.3e-17 63.8 0.6 4.5e-17 62.1 0.6 1.8 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EGG13219.1 - 7.7e-17 61.2 0.6 1.3e-10 40.7 0.3 2.8 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGG13219.1 - 1.6e-12 47.2 1.4 3.2e-06 26.5 0.4 2.7 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGG13219.1 - 2.3e-07 30.2 0.0 3.4e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EGG13219.1 - 0.0013 18.7 0.0 0.053 13.4 0.1 2.5 2 1 0 2 2 2 1 KR domain NmrA PF05368.13 EGG13219.1 - 0.0049 16.4 0.1 0.016 14.8 0.1 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGG13219.1 - 0.01 15.8 0.0 0.84 9.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 EGG13219.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase F-box-like PF12937.7 EGG13220.1 - 2.3 8.2 6.9 8.6 6.4 6.9 2.1 1 1 0 1 1 1 0 F-box-like zf-CCHC PF00098.23 EGG13226.1 - 0.018 15.1 1.7 0.034 14.2 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 EGG13226.1 - 0.16 11.8 0.3 0.34 10.8 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Adaptin_N PF01602.20 EGG13227.1 - 6.6e-18 64.6 4.8 3.1e-16 59.1 4.8 2.0 1 1 0 1 1 1 1 Adaptin N terminal region Rad60-SLD PF11976.8 EGG13228.1 - 3.5e-13 49.2 0.7 2.4e-10 40.1 1.3 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGG13228.1 - 0.13 12.0 0.4 0.4 10.5 0.4 1.9 1 1 0 1 1 1 0 Ubiquitin family ETF PF01012.21 EGG13230.1 - 5e-38 130.8 0.0 7.4e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EGG13230.1 - 6.2e-33 112.7 0.1 1.6e-32 111.3 0.1 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain DnaJ PF00226.31 EGG13231.1 - 3.8e-12 46.2 0.8 5.1e-11 42.5 0.8 2.2 1 1 0 1 1 1 1 DnaJ domain Glycos_transf_2 PF00535.26 EGG13232.1 - 0.0032 17.3 3.5 0.25 11.1 0.5 2.5 1 1 1 2 2 2 2 Glycosyl transferase family 2 DUF4944 PF16302.5 EGG13233.1 - 0.018 15.1 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) PAP_RNA-bind PF04926.15 EGG13233.1 - 0.024 14.3 0.2 0.028 14.0 0.2 1.1 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain PDH PF02153.17 EGG13235.1 - 1.1e-14 54.1 0.0 1.5e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 EGG13235.1 - 3.7e-07 30.6 0.0 1.2e-06 29.0 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EGG13235.1 - 7.6e-05 22.9 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EGG13235.1 - 0.0025 17.9 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EGG13235.1 - 0.019 14.4 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EGG13235.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.16 EGG13236.1 - 4.7e-28 98.1 23.1 4.7e-28 98.1 23.1 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGG13236.1 - 1.9e-06 27.5 4.7 1.9e-06 27.5 4.7 2.2 1 1 2 3 3 3 1 Uncharacterised MFS-type transporter YbfB Ribosomal_S10 PF00338.22 EGG13237.1 - 5.5e-29 100.3 0.3 6.4e-29 100.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 EGG13237.1 - 0.11 13.3 0.0 0.22 12.3 0.0 1.4 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain ChaC PF04752.12 EGG13239.1 - 1.4e-56 191.3 0.0 1.6e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein AIG2_2 PF13772.6 EGG13239.1 - 0.0049 17.2 0.2 0.0077 16.6 0.2 1.4 1 0 0 1 1 1 1 AIG2-like family DUF4038 PF13204.6 EGG13239.1 - 0.015 14.9 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) LRR_3 PF07725.12 EGG13239.1 - 0.16 11.9 0.6 0.35 10.8 0.6 1.5 1 0 0 1 1 1 0 Leucine Rich Repeat SURNod19 PF07712.12 EGG13242.1 - 0.022 13.5 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Stress up-regulated Nod 19 XkdW PF09636.10 EGG13245.1 - 0.0065 16.6 0.8 0.024 14.7 0.8 2.0 1 0 0 1 1 1 1 XkdW protein Ribosomal_L37 PF08561.10 EGG13246.1 - 6.7e-20 71.8 4.2 5.7e-15 55.9 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 DEC-1_N PF04625.13 EGG13247.1 - 0.03 13.3 2.1 0.042 12.9 2.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RmlD_sub_bind PF04321.17 EGG13248.1 - 2.3e-20 72.9 0.1 1.1e-17 64.1 0.1 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGG13248.1 - 9.5e-08 31.8 0.1 0.0068 15.9 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGG13248.1 - 0.0032 16.6 0.0 0.94 8.5 0.0 2.0 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EGG13248.1 - 0.011 15.2 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGG13249.1 - 3.4e-06 26.4 0.0 4.3e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain UNC-93 PF05978.16 EGG13250.1 - 2.2e-15 56.7 5.0 5.7e-15 55.4 5.0 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EGG13250.1 - 1.3e-10 40.8 29.7 1.3e-10 40.8 29.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily ABC2_membrane_5 PF13346.6 EGG13250.1 - 0.0052 16.4 6.4 0.0052 16.4 6.4 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein MFS_1_like PF12832.7 EGG13250.1 - 0.0076 15.1 6.3 0.0076 15.1 6.3 1.7 1 1 0 1 1 1 1 MFS_1 like family Ysc84 PF04366.12 EGG13250.1 - 0.07 12.9 0.5 0.22 11.3 0.0 2.1 2 1 0 2 2 2 0 Las17-binding protein actin regulator HPP PF04982.13 EGG13251.1 - 9.4e-32 109.8 4.5 1.4e-31 109.2 4.5 1.3 1 0 0 1 1 1 1 HPP family La PF05383.17 EGG13252.1 - 2.2e-10 40.4 0.9 8.1e-09 35.4 0.9 2.6 1 1 0 1 1 1 1 La domain DUF743 PF05332.11 EGG13252.1 - 0.053 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF743) PPTA PF01239.22 EGG13253.1 - 9.9e-41 136.3 21.7 5.9e-10 38.5 0.3 5.8 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF3950 PF13132.6 EGG13253.1 - 0.023 14.5 0.8 11 5.8 1.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) K_oxygenase PF13434.6 EGG13254.1 - 8.1e-09 35.1 0.0 0.00082 18.6 0.0 3.9 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EGG13254.1 - 0.0014 17.9 0.5 0.12 11.6 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG13254.1 - 0.058 13.4 0.1 15 5.5 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 EGG13254.1 - 0.11 12.0 0.3 24 4.3 0.0 3.3 4 0 0 4 4 4 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG13254.1 - 0.24 10.6 0.4 42 3.2 0.0 3.2 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase zf-CCHC PF00098.23 EGG13255.1 - 0.0041 17.1 2.0 0.0082 16.2 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Melampsora_larici-populina_98AG31-v1.0/GCA_000204055.1_v1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Melampsora_larici-populina_98AG31-v1.0/GCA_000204055.1_v1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Melampsora_larici-populina_98AG31-v1.0/GCA_000204055.1_v1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Melampsora_larici-populina_98AG31-v1.0/GCA_000204055.1_v1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 23:55:03 2019 # [ok]