# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- CFEM PF05730.6 EGF96883.1 - 0.00042 20.0 0.5 0.18 11.6 0.1 2.3 2 0 0 2 2 2 2 CFEM domain MdoG PF04349.7 EGF96884.1 - 0.14 10.3 0.1 0.19 9.9 0.1 1.1 1 0 0 1 1 1 0 Periplasmic glucan biosynthesis protein, MdoG SWIM PF04434.12 EGF96886.1 - 0.00094 18.6 0.6 0.0016 17.8 0.4 1.4 1 0 0 1 1 1 1 SWIM zinc finger POP1 PF06978.6 EGF96888.1 - 0.14 11.7 5.8 0.19 11.4 4.0 1.1 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 DUF1682 PF07946.9 EGF96888.1 - 4.6 5.9 12.8 6.2 5.5 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF904 PF06005.7 EGF96889.1 - 0.094 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) RNA_pol_3_Rpc31 PF11705.3 EGF96890.1 - 5.1 6.9 34.3 6.1 6.7 23.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DDHD PF02862.12 EGF96890.1 - 6 6.5 6.0 6.6 6.4 4.2 1.1 1 0 0 1 1 1 0 DDHD domain DUF2931 PF11153.3 EGF96891.1 - 2.2e-44 151.3 0.0 3.4e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2931) DUF2235 PF09994.4 EGF96891.1 - 2.8e-28 99.1 0.0 8.5e-26 90.9 0.0 2.9 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2345 PF10106.4 EGF96891.1 - 0.021 14.4 0.1 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Mn_catalase PF05067.7 EGF96892.1 - 2.9e-86 288.7 0.0 2.6e-85 285.6 0.0 1.9 1 1 0 1 1 1 1 Manganese containing catalase Rubrerythrin PF02915.12 EGF96892.1 - 0.0062 16.8 0.0 0.13 12.5 0.0 2.1 1 1 0 1 1 1 1 Rubrerythrin TFIIS_C PF01096.13 EGF96895.1 - 4.5e-16 58.1 7.9 7.8e-16 57.4 0.6 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGF96895.1 - 0.00024 20.7 12.4 0.00051 19.6 1.6 3.1 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit VP_N-CPKC PF11475.3 EGF96895.1 - 0.00025 20.5 1.5 0.45 10.0 0.0 2.6 2 0 0 2 2 2 2 Virion protein N terminal domain DZR PF12773.2 EGF96895.1 - 0.00042 20.0 6.8 0.22 11.3 0.2 2.6 2 1 0 2 2 2 2 Double zinc ribbon Lar_restr_allev PF14354.1 EGF96895.1 - 0.0012 19.1 5.8 0.02 15.1 0.4 3.1 2 1 0 2 2 2 1 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 EGF96895.1 - 0.0023 17.0 12.5 0.29 10.3 1.4 3.4 3 1 0 3 3 3 2 zinc-ribbon domain HypA PF01155.14 EGF96895.1 - 0.0027 17.3 5.0 0.1 12.3 0.0 3.0 2 1 0 2 2 2 1 Hydrogenase expression/synthesis hypA family IBR PF01485.16 EGF96895.1 - 0.0058 16.4 3.1 0.16 11.8 0.2 2.4 2 0 0 2 2 2 1 IBR domain zf-RING_3 PF14369.1 EGF96895.1 - 0.019 14.9 3.6 15 5.6 0.1 3.3 3 0 0 3 3 3 0 zinc-finger tRNA-synt_1f PF01921.13 EGF96895.1 - 0.024 13.3 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) zf-ISL3 PF14690.1 EGF96895.1 - 0.026 14.5 4.4 7.8 6.6 0.3 3.4 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-H2C2_2 PF13465.1 EGF96895.1 - 0.03 14.6 0.5 0.03 14.6 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 EGF96895.1 - 0.032 14.1 10.8 0.91 9.5 0.7 3.6 3 1 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 EGF96895.1 - 0.035 13.6 15.3 0.18 11.3 0.2 3.8 3 1 0 3 3 3 0 zinc-ribbon domain Terminase_GpA PF05876.7 EGF96895.1 - 0.037 12.3 1.6 0.058 11.7 0.6 1.6 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) Antiterm PF03589.8 EGF96895.1 - 0.041 13.9 1.4 3.5 7.7 0.0 2.5 1 1 0 2 2 2 0 Antitermination protein zf-C4_Topoisom PF01396.14 EGF96895.1 - 0.046 13.2 10.6 5.6 6.5 0.1 3.7 4 0 0 4 4 3 0 Topoisomerase DNA binding C4 zinc finger Ogr_Delta PF04606.7 EGF96895.1 - 0.047 13.3 1.5 0.047 13.3 1.0 2.7 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger DUF2082 PF09855.4 EGF96895.1 - 0.09 12.6 8.8 11 5.9 0.2 3.6 4 0 0 4 4 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Vel1p PF10339.4 EGF96895.1 - 0.091 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Yeast-specific zinc responsive zf-C2H2_4 PF13894.1 EGF96895.1 - 0.12 12.7 8.1 0.36 11.2 0.7 3.5 4 0 0 4 4 3 0 C2H2-type zinc finger DUF2387 PF09526.5 EGF96895.1 - 0.14 12.1 5.8 0.24 11.3 0.3 2.8 2 1 1 3 3 2 0 Probable metal-binding protein (DUF2387) Baculo_LEF5_C PF11792.3 EGF96895.1 - 0.15 11.4 0.0 0.15 11.4 0.0 2.7 3 0 0 3 3 2 0 Baculoviridae late expression factor 5 C-terminal domain Nudix_N_2 PF14803.1 EGF96895.1 - 0.18 11.4 7.2 23 4.7 0.1 4.1 4 0 0 4 4 4 0 Nudix N-terminal UPF0547 PF10571.4 EGF96895.1 - 0.18 11.4 0.7 0.18 11.4 0.5 3.5 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-CSL PF05207.8 EGF96895.1 - 0.28 10.7 0.1 0.28 10.7 0.1 3.1 3 1 0 3 3 3 0 CSL zinc finger Ribosomal_S27e PF01667.12 EGF96895.1 - 0.41 10.2 6.4 8.7 5.9 0.4 3.8 3 1 0 3 3 3 0 Ribosomal protein S27 C1_1 PF00130.17 EGF96895.1 - 0.46 10.2 0.1 0.46 10.2 0.1 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-TFIIB PF13453.1 EGF96895.1 - 0.63 9.2 7.5 0.093 11.9 1.3 2.4 2 1 0 2 2 2 0 Transcription factor zinc-finger zinc-ribbons_6 PF07191.7 EGF96895.1 - 0.72 9.6 6.7 6.3 6.6 1.5 2.7 2 1 0 2 2 2 0 zinc-ribbons Rpr2 PF04032.11 EGF96895.1 - 0.83 9.5 9.4 0.029 14.2 0.6 2.7 1 1 1 2 2 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Prok-RING_1 PF14446.1 EGF96895.1 - 1.1 9.0 8.5 14 5.4 0.8 3.4 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 ADK_lid PF05191.9 EGF96895.1 - 1.2 8.9 10.2 7 6.4 0.9 3.7 3 1 0 3 3 3 0 Adenylate kinase, active site lid TerY-C PF15616.1 EGF96895.1 - 1.3 8.9 8.5 2.9 7.8 0.2 2.8 1 1 1 2 2 2 0 TerY-C metal binding domain DUF1610 PF07754.6 EGF96895.1 - 1.9 8.6 13.5 1.3 9.1 0.5 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) zf-Mss51 PF13824.1 EGF96895.1 - 2.5 8.0 7.4 0.46 10.3 0.7 2.8 3 1 0 3 3 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn_Tnp_IS1595 PF12760.2 EGF96895.1 - 2.5 7.9 12.0 14 5.6 4.3 3.3 2 2 1 3 3 3 0 Transposase zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EGF96895.1 - 3 7.3 8.7 4.8 6.7 0.3 3.0 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit TF_Zn_Ribbon PF08271.7 EGF96895.1 - 3.1 7.1 13.3 3.1 7.2 0.4 3.6 3 1 0 3 3 3 0 TFIIB zinc-binding zf-C2HC5 PF06221.8 EGF96895.1 - 3.3 7.5 9.5 1 9.1 0.4 3.2 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type A2L_zn_ribbon PF08792.5 EGF96895.1 - 3.4 7.2 13.6 25 4.4 0.1 4.2 4 0 0 4 4 4 0 A2L zinc ribbon domain zinc_ribbon_5 PF13719.1 EGF96895.1 - 3.7 7.2 10.8 1.6 8.4 0.3 3.5 4 0 0 4 4 3 0 zinc-ribbon domain Methyltransf_13 PF08421.6 EGF96895.1 - 3.9 7.0 8.6 1.2 8.7 0.1 3.3 4 0 0 4 4 4 0 Putative zinc binding domain zf-AN1 PF01428.11 EGF96895.1 - 3.9 7.4 6.5 13 5.7 0.1 3.1 3 1 0 3 3 3 0 AN1-like Zinc finger CpXC PF14353.1 EGF96895.1 - 3.9 7.4 9.1 2.6 8.0 1.5 3.2 2 2 0 2 2 2 0 CpXC protein zinc_ribbon_4 PF13717.1 EGF96895.1 - 4.4 7.0 10.6 1.5 8.5 0.2 3.5 4 0 0 4 4 3 0 zinc-ribbon domain Auto_anti-p27 PF06677.7 EGF96895.1 - 6.3 6.6 12.0 0.85 9.4 0.2 3.5 4 0 0 4 4 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.6 EGF96895.1 - 6.7 6.4 8.2 17 5.1 0.2 2.8 2 2 0 2 2 2 0 Putative transposase DNA-binding domain DUF3797 PF12677.2 EGF96895.1 - 7.2 6.3 13.9 8.8 6.0 0.1 3.9 2 2 2 4 4 4 0 Domain of unknown function (DUF3797) zf-C3HC4_4 PF15227.1 EGF96895.1 - 9.1 6.2 8.1 3.7 7.5 0.6 3.0 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING DUF2197 PF09963.4 EGF96897.1 - 0.02 14.8 0.4 0.71 9.8 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Imm30 PF15594.1 EGF96897.1 - 0.045 13.8 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Immunity protein 30 MRC1 PF09444.5 EGF96898.1 - 0.038 14.3 2.9 0.062 13.6 2.0 1.3 1 0 0 1 1 1 0 MRC1-like domain VirE2 PF07229.7 EGF96898.1 - 0.051 11.9 2.1 0.064 11.6 1.5 1.0 1 0 0 1 1 1 0 VirE2 TMF_DNA_bd PF12329.3 EGF96899.1 - 0.068 12.9 1.4 0.19 11.5 1.0 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3782 PF12644.2 EGF96899.1 - 0.069 12.9 0.3 0.094 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) End3 PF12761.2 EGF96899.1 - 0.23 11.0 1.3 0.38 10.3 0.9 1.4 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Mito_carr PF00153.22 EGF96900.1 - 4.3e-08 32.7 0.0 4.3e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein MarB PF13999.1 EGF96901.1 - 0.07 12.7 1.0 2.2 7.9 0.0 2.9 3 0 0 3 3 3 0 MarB protein DnaJ PF00226.26 EGF96904.1 - 1e-08 34.7 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Syntaxin-6_N PF09177.6 EGF96905.1 - 0.089 13.1 0.3 3.9 7.9 0.0 2.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal MOZ_SAS PF01853.13 EGF96906.1 - 8.8e-17 60.9 0.1 1e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 MOZ/SAS family HTH_6 PF01418.12 EGF96906.1 - 0.0034 17.0 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family YIEGIA PF14045.1 EGF96906.1 - 0.027 13.0 0.0 0.03 12.9 0.0 1.1 1 0 0 1 1 1 0 YIEGIA protein HTH_IclR PF09339.5 EGF96906.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain Astacin PF01400.19 EGF96906.1 - 0.13 11.6 1.9 0.16 11.3 1.3 1.1 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) ATP-synt_C PF00137.16 EGF96908.1 - 2.6e-18 65.6 10.1 2.9e-18 65.5 7.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit C ABC2_membrane_4 PF12730.2 EGF96908.1 - 0.32 10.1 5.0 0.39 9.8 3.5 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Oxidored_q1 PF00361.15 EGF96909.1 - 8.6e-13 48.1 15.3 2e-07 30.5 3.0 4.0 1 1 1 2 2 2 2 NADH-Ubiquinone/plastoquinone (complex I), various chains FtsH_ext PF06480.10 EGF96911.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsH Extracellular NSP2-B_epitope PF14757.1 EGF96913.1 - 0.039 13.4 0.7 0.053 12.9 0.5 1.2 1 1 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein DUF1154 PF06631.6 EGF96913.1 - 0.14 11.8 1.1 0.25 11.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) Peptidase_M8 PF01457.11 EGF96914.1 - 0.0041 15.5 0.0 0.0062 14.9 0.0 1.2 1 0 0 1 1 1 1 Leishmanolysin DS PF01916.12 EGF96917.1 - 1e-20 74.1 0.0 1.1e-20 73.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF1005 PF06219.7 EGF96918.1 - 0.021 13.5 0.5 0.033 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) DUF2366 PF10171.4 EGF96918.1 - 0.027 13.9 0.3 0.063 12.7 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2366) MAS20 PF02064.10 EGF96919.1 - 0.0073 16.2 0.1 0.012 15.5 0.1 1.4 1 1 0 1 1 1 1 MAS20 protein import receptor ACT_5 PF13710.1 EGF96919.1 - 0.011 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 ACT domain AAA_24 PF13479.1 EGF96919.1 - 0.021 14.4 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain FAD_binding_4 PF01565.18 EGF96920.1 - 4.3e-10 39.1 0.2 5.9e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Gal_mutarotas_2 PF13802.1 EGF96925.1 - 6.4e-09 35.5 0.1 7.7e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Galactose mutarotase-like Spermine_synth PF01564.12 EGF96926.1 - 2.7e-55 186.9 0.0 3.7e-32 111.2 0.0 2.7 2 1 1 3 3 3 2 Spermine/spermidine synthase Saccharop_dh PF03435.13 EGF96926.1 - 2.2e-49 168.4 0.1 4.3e-48 164.2 0.1 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase Dicty_REP PF05086.7 EGF96927.1 - 0.022 12.5 2.9 0.025 12.3 2.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 EGF96927.1 - 0.035 13.8 8.2 0.046 13.5 5.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Trs65 PF12735.2 EGF96927.1 - 0.04 13.2 5.2 0.049 12.9 3.6 1.3 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Alpha_kinase PF02816.13 EGF96928.1 - 1.8e-07 31.0 0.1 2.7e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family ABC_tran PF00005.22 EGF96933.1 - 3.8e-14 53.1 0.0 4.8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGF96933.1 - 1.6e-06 28.3 1.2 1.9e-05 24.7 0.5 2.1 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EGF96933.1 - 0.00017 21.4 0.0 0.00068 19.5 0.0 1.9 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF702 PF05142.7 EGF96934.1 - 0.018 15.2 4.5 0.038 14.1 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Cu-oxidase PF00394.17 EGF96935.1 - 5.4e-07 29.6 0.0 6.2e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Multicopper oxidase zf-CCHC_6 PF15288.1 EGF96937.1 - 0.034 13.8 0.2 0.082 12.5 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EGF96937.1 - 0.07 13.0 1.0 0.12 12.3 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle LdpA_C PF12617.3 EGF96940.1 - 0.017 14.3 0.5 0.034 13.4 0.4 1.6 1 1 0 1 1 1 0 Iron-Sulfur binding protein C terminal Rad33 PF08730.5 EGF96942.1 - 0.04 13.3 0.2 0.07 12.5 0.1 1.3 1 0 0 1 1 1 0 Rad33 TerB-C PF15615.1 EGF96944.1 - 0.029 14.6 0.6 0.053 13.7 0.4 1.3 1 0 0 1 1 1 0 TerB-C domain Prp19 PF08606.6 EGF96944.1 - 0.19 11.4 0.9 0.6 9.8 0.0 2.2 3 0 0 3 3 3 0 Prp19/Pso4-like Rad33 PF08730.5 EGF96947.1 - 0.019 14.4 0.1 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Rad33 Spore_GerAC PF05504.6 EGF96947.1 - 0.068 12.9 0.2 0.099 12.4 0.1 1.5 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal DUF3490 PF11995.3 EGF96947.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) Ras PF00071.17 EGF96948.1 - 5.4e-26 90.9 0.0 1.9e-25 89.0 0.0 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGF96948.1 - 6.3e-05 23.4 0.0 0.0013 19.2 0.0 2.4 1 1 0 2 2 2 1 Miro-like protein Alpha_kinase PF02816.13 EGF96951.1 - 4.9e-12 45.8 0.0 6.1e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family DUF309 PF03745.9 EGF96954.1 - 0.022 14.2 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF309) UBN2 PF14223.1 EGF96955.1 - 9e-06 25.4 0.0 3.7e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGF96955.1 - 0.0002 20.8 0.0 0.00065 19.2 0.0 1.8 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TraK PF06586.6 EGF96956.1 - 0.015 14.4 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 TraK protein DUF1128 PF06569.6 EGF96956.1 - 0.091 12.4 1.3 0.16 11.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) SNARE PF05739.14 EGF96956.1 - 0.16 11.6 0.4 0.16 11.6 0.3 2.5 3 0 0 3 3 3 0 SNARE domain BLOC1_2 PF10046.4 EGF96956.1 - 0.23 11.6 3.6 0.33 11.1 0.2 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ING PF12998.2 EGF96956.1 - 0.26 11.5 3.1 0.42 10.9 1.4 1.9 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding OmpH PF03938.9 EGF96956.1 - 0.35 10.7 8.1 0.76 9.6 5.4 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Cytochrom_B562 PF07361.6 EGF96956.1 - 0.36 11.2 6.3 0.5 10.8 2.1 2.3 2 1 1 3 3 3 0 Cytochrome b562 DUF4200 PF13863.1 EGF96956.1 - 1.6 8.6 14.0 1.7 8.5 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF3135 PF11333.3 EGF96956.1 - 2.4 8.3 5.9 0.94 9.6 1.1 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3135) DUF4559 PF15112.1 EGF96956.1 - 4.6 6.3 7.9 0.63 9.1 1.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4559) LEH PF07858.7 EGF96959.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain LTV PF04180.9 EGF96960.1 - 0.086 12.3 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Low temperature viability protein zf-CCHC PF00098.18 EGF96962.1 - 0.0019 18.0 2.6 0.0019 18.0 1.8 1.8 2 0 0 2 2 2 1 Zinc knuckle UBN2 PF14223.1 EGF96962.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type BRO1 PF03097.13 EGF96964.1 - 1e-40 139.6 0.0 1.1e-40 139.5 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain Iso_dh PF00180.15 EGF96965.1 - 0.00019 20.5 0.0 0.00022 20.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RPAP3_C PF13877.1 EGF96967.1 - 0.12 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Acyl-CoA_dh_1 PF00441.19 EGF96969.1 - 2e-17 63.7 0.3 2.4e-17 63.4 0.2 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EGF96969.1 - 0.00072 19.8 0.2 0.001 19.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-CCHC_3 PF13917.1 EGF96972.1 - 0.0002 21.0 0.6 0.00044 19.9 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle MGC-24 PF05283.6 EGF96972.1 - 3.3 7.4 10.2 9.3 6.0 6.8 2.0 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF1325 PF07039.6 EGF96974.1 - 6.5e-23 80.7 0.0 1.2e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain PXA PF02194.10 EGF96977.1 - 0.18 11.3 1.5 0.17 11.4 0.2 1.6 2 0 0 2 2 2 0 PXA domain Plasmid_stabil PF05016.9 EGF96978.1 - 0.011 16.0 0.7 0.44 10.9 0.1 2.3 2 0 0 2 2 2 0 Plasmid stabilisation system protein Glyco_hydro_12 PF01670.11 EGF96979.1 - 6.9e-14 51.9 0.1 9.5e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Myb_DNA-binding PF00249.26 EGF96984.1 - 9.2e-24 83.2 5.6 7.3e-12 45.1 0.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGF96984.1 - 4.2e-22 78.0 9.4 2.8e-14 52.9 2.8 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.1 EGF96984.1 - 0.017 14.6 0.0 0.067 12.7 0.0 2.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Rap1_C PF11626.3 EGF96984.1 - 0.17 11.7 1.2 3.4 7.6 0.1 2.5 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ATC_hydrolase PF14196.1 EGF96984.1 - 0.37 11.1 3.5 8.7 6.7 0.0 2.2 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Keratin_B2 PF01500.12 EGF96986.1 - 0.028 14.1 3.3 0.031 14.0 0.6 2.3 2 1 1 3 3 3 0 Keratin, high sulfur B2 protein zf-CCHC PF00098.18 EGF96988.1 - 0.0014 18.4 0.9 0.0014 18.4 0.6 2.9 3 0 0 3 3 3 1 Zinc knuckle Cortex-I_coil PF09304.5 EGF96988.1 - 0.0072 16.3 3.0 0.014 15.4 2.1 1.4 1 0 0 1 1 1 1 Cortexillin I, coiled coil zf-CCHC_4 PF14392.1 EGF96988.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Zinc knuckle LUC7 PF03194.10 EGF96988.1 - 0.25 10.8 3.6 4.6 6.6 2.0 2.2 1 1 1 2 2 2 0 LUC7 N_terminus UBN2 PF14223.1 EGF96989.1 - 0.0022 17.7 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGF96989.1 - 0.0091 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Dicty_REP PF05086.7 EGF96989.1 - 0.041 11.6 0.0 0.053 11.2 0.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HEV_ORF1 PF02444.11 EGF96993.1 - 0.12 12.5 0.9 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) DUF488 PF04343.8 EGF96993.1 - 0.72 10.2 6.0 0.67 10.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF488 DUF959 PF06121.9 EGF96994.1 - 0.078 12.6 0.3 0.091 12.4 0.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) IDO PF01231.13 EGF96995.1 - 3.2e-15 55.5 0.0 4.2e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Pro-rich PF15240.1 EGF96997.1 - 3.7 7.6 39.9 4.3 7.3 27.7 1.1 1 0 0 1 1 1 0 Proline-rich DUF4659 PF15558.1 EGF96997.1 - 4.1 5.9 8.0 5.3 5.6 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4659) Nop14 PF04147.7 EGF96997.1 - 4.9 4.9 10.8 5.6 4.7 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family Zn_clus PF00172.13 EGF97000.1 - 3.1e-05 23.8 2.8 4.3e-05 23.3 2.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.4 EGF97000.1 - 0.11 11.0 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein HMG_box_5 PF14887.1 EGF97001.1 - 9.8e-07 28.4 16.8 8.9 6.1 0.1 6.4 6 0 0 6 6 6 6 HMG (high mobility group) box 5 Lac_bphage_repr PF06543.7 EGF97001.1 - 1.1e-06 28.0 7.8 15 5.1 0.0 7.1 7 0 0 7 7 7 3 Lactococcus bacteriophage repressor MAPKK1_Int PF08923.5 EGF97001.1 - 0.0011 18.5 1.8 1.5e+02 2.0 0.0 5.6 6 0 0 6 6 6 0 Mitogen-activated protein kinase kinase 1 interacting STOP PF05217.7 EGF97001.1 - 0.0012 18.6 2.4 43 3.7 0.0 4.6 5 0 0 5 5 5 0 STOP protein 3-alpha PF03475.9 EGF97001.1 - 0.041 13.6 14.2 1.1e+02 2.6 0.0 7.0 7 0 0 7 7 7 0 3-alpha domain Nicastrin PF05450.10 EGF97001.1 - 4.3 6.4 6.8 19 4.4 0.0 4.2 5 0 0 5 5 5 0 Nicastrin CotH PF08757.6 EGF97002.1 - 0.059 12.6 1.3 0.069 12.3 0.9 1.0 1 0 0 1 1 1 0 CotH protein AIF_C PF14721.1 EGF97002.1 - 0.079 13.2 1.0 0.098 12.9 0.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Phyto_Pns9_10 PF05878.6 EGF97002.1 - 0.16 10.9 1.0 0.19 10.7 0.7 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DDHD PF02862.12 EGF97008.1 - 2.1 8.0 8.2 3.7 7.2 5.7 1.5 1 0 0 1 1 1 0 DDHD domain DUF4407 PF14362.1 EGF97008.1 - 7.9 5.3 8.5 12 4.7 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WD40 PF00400.27 EGF97011.1 - 1.3e-10 40.7 0.1 3.1e-05 23.6 0.1 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Mo-co_dimer PF03404.11 EGF97011.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain TSGP1 PF07771.6 EGF97013.1 - 2.9 7.8 10.1 0.11 12.4 2.6 1.8 2 0 0 2 2 2 0 Tick salivary peptide group 1 Ketoacyl-synt_2 PF13723.1 EGF97014.1 - 0.18 11.0 0.0 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain MCPVI PF02993.9 EGF97014.1 - 1.4 9.0 4.7 5.4 7.1 2.9 2.1 2 0 0 2 2 2 0 Minor capsid protein VI ORC6 PF05460.8 EGF97026.1 - 1.5 7.8 15.3 5.7 5.9 10.6 2.0 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) VirD1 PF07328.6 EGF97028.1 - 0.044 13.5 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 PRP21_like_P PF12230.3 EGF97029.1 - 8.3e-40 136.7 22.7 8.3e-40 136.7 15.7 3.1 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EGF97029.1 - 4e-28 96.8 0.7 1.7e-13 49.9 0.1 2.5 2 0 0 2 2 2 2 Surp module Gly_radical PF01228.16 EGF97029.1 - 0.008 16.5 0.5 0.028 14.7 0.3 1.9 1 0 0 1 1 1 1 Glycine radical Adaptin_binding PF10199.4 EGF97029.1 - 1.2 9.4 19.3 0.052 13.8 3.7 2.6 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF605 PF04652.11 EGF97031.1 - 2.8 7.2 9.6 3.8 6.8 6.7 1.2 1 0 0 1 1 1 0 Vta1 like Viral_Beta_CD PF04530.7 EGF97033.1 - 0.015 15.4 0.1 0.64 10.1 0.0 2.9 2 1 1 3 3 3 0 Viral Beta C/D like family HTH_Tnp_4 PF13613.1 EGF97034.1 - 0.062 12.8 0.1 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease Alpha_kinase PF02816.13 EGF97035.1 - 1e-09 38.3 0.0 8.8e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 Alpha-kinase family Pkinase PF00069.20 EGF97037.1 - 7.6e-18 64.5 0.0 8e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF97037.1 - 6.8e-12 45.0 0.0 7.1e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGF97038.1 - 0.018 14.1 0.0 0.019 14.1 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain ParA PF10609.4 EGF97040.1 - 1.5e-29 101.7 0.0 3.4e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGF97040.1 - 3.4e-10 39.6 0.0 8.3e-10 38.3 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EGF97040.1 - 8.1e-07 28.3 0.0 6.1e-05 22.2 0.0 2.2 1 1 1 2 2 2 2 ATPase MipZ AAA_31 PF13614.1 EGF97040.1 - 3.8e-05 23.6 0.0 0.00014 21.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EGF97040.1 - 0.00022 20.3 0.8 0.00051 19.1 0.2 2.0 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EGF97040.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGF97040.1 - 0.12 12.1 2.2 0.39 10.4 0.1 2.6 3 0 0 3 3 3 0 Part of AAA domain RIO1 PF01163.17 EGF97046.1 - 4e-28 98.0 1.1 3.3e-19 68.9 0.1 2.0 1 1 1 2 2 2 2 RIO1 family Glyco_hydro_7 PF00840.15 EGF97047.1 - 2.5e-193 642.3 15.5 3e-193 642.0 10.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 GBP_PSP PF02425.10 EGF97048.1 - 0.00096 18.6 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Paralytic/GBP/PSP peptide GYF PF02213.11 EGF97049.1 - 0.0011 18.5 0.8 0.0013 18.2 0.2 1.4 1 1 0 1 1 1 1 GYF domain Glyco_hydro_15 PF00723.16 EGF97051.1 - 4.5e-56 190.2 0.3 5.4e-56 190.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Adeno_52K PF03052.10 EGF97051.1 - 0.039 13.1 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa Methyltrn_RNA_2 PF04013.7 EGF97052.1 - 0.0046 16.5 0.1 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 Putative SAM-dependent RNA methyltransferase DUF4164 PF13747.1 EGF97053.1 - 0.0069 16.5 9.7 0.028 14.5 1.7 3.0 3 1 1 4 4 4 2 Domain of unknown function (DUF4164) CheZ PF04344.8 EGF97053.1 - 0.44 10.1 8.7 1.1 8.9 6.0 1.6 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ Baculo_PEP_C PF04513.7 EGF97053.1 - 3.3 7.5 11.8 3.2 7.5 4.8 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 EGF97053.1 - 9.2 4.5 9.1 15 3.8 6.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Sad1_UNC PF07738.8 EGF97056.1 - 1.2e-27 96.3 0.0 2.3e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal NPV_P10 PF05531.7 EGF97056.1 - 0.095 12.9 1.7 1.3 9.3 0.5 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MerR-DNA-bind PF09278.6 EGF97056.1 - 0.11 12.9 2.6 54 4.2 0.0 3.4 3 0 0 3 3 3 0 MerR, DNA binding DivIC PF04977.10 EGF97056.1 - 9.9 5.7 8.6 4.8 6.7 0.2 3.1 2 1 1 3 3 3 0 Septum formation initiator Flavoprotein PF02441.14 EGF97058.1 - 1.3e-40 138.0 0.0 2.4e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein PAP2 PF01569.16 EGF97060.1 - 2.7e-19 69.1 3.4 2.7e-19 69.1 2.4 1.4 2 0 0 2 2 2 1 PAP2 superfamily Fanconi_A PF03511.9 EGF97060.1 - 0.062 13.0 0.1 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Fanconi anaemia group A protein PolyA_pol PF01743.15 EGF97062.1 - 1.9e-09 37.8 0.2 5.6e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Poly A polymerase head domain Helicase_C PF00271.26 EGF97067.1 - 4.5e-09 36.0 0.0 8e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SHMT PF00464.14 EGF97068.1 - 6.8e-23 80.6 0.0 7.6e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase MBOAT PF03062.14 EGF97071.1 - 1.1e-35 123.3 8.9 1.1e-35 123.3 6.2 1.7 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Tho2 PF11262.3 EGF97073.1 - 1 8.3 6.7 0.11 11.4 1.5 1.6 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 COG2 PF06148.6 EGF97074.1 - 0.00024 21.0 0.7 0.00062 19.6 0.3 1.8 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 EGF97074.1 - 0.00053 19.8 1.5 0.0011 18.8 1.0 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 EGF97074.1 - 0.0032 16.9 0.3 0.0073 15.8 0.2 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4164 PF13747.1 EGF97074.1 - 0.0041 17.2 1.5 0.01 15.9 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) ApoLp-III PF07464.6 EGF97074.1 - 0.015 15.2 2.1 0.018 15.0 0.6 1.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) NifU_N PF01592.11 EGF97074.1 - 0.021 14.7 0.1 0.059 13.3 0.0 1.7 2 0 0 2 2 2 0 NifU-like N terminal domain Ferritin-like PF12902.2 EGF97074.1 - 0.046 13.3 0.1 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like DUF948 PF06103.6 EGF97074.1 - 0.05 13.4 1.5 0.13 12.1 1.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.8 EGF97074.1 - 0.091 13.1 2.6 0.22 11.9 0.3 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Bacillus_HBL PF05791.6 EGF97074.1 - 0.18 11.1 1.7 0.39 10.0 1.2 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF724 PF05266.9 EGF97074.1 - 0.24 10.9 2.0 1.4 8.5 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.7 EGF97074.1 - 0.85 9.4 3.6 2.7 7.7 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EGF97074.1 - 1 9.6 3.4 8 6.8 2.4 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PBP1_TM PF14812.1 EGF97075.1 - 1.6 9.0 6.8 4.3 7.7 4.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAR1 PF03101.10 EGF97076.1 - 9.1e-06 26.1 1.7 9.1e-06 26.1 1.2 1.7 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.6 EGF97076.1 - 0.012 15.7 1.0 0.012 15.7 0.7 2.1 2 0 0 2 2 2 0 Transcription factor AFT DUF3505 PF12013.3 EGF97080.1 - 0.0016 18.6 2.5 0.015 15.5 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) DUF1724 PF08350.5 EGF97080.1 - 0.09 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) NPV_P10 PF05531.7 EGF97083.1 - 0.027 14.7 0.2 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4548 PF15081.1 EGF97085.1 - 0.083 12.4 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4548) Acyl-CoA_dh_1 PF00441.19 EGF97087.1 - 5.7e-24 84.9 0.0 9.2e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGF97087.1 - 1.7e-22 80.1 0.0 3.5e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGF97087.1 - 2.6e-17 62.0 0.2 5e-17 61.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGF97087.1 - 3.3e-07 30.6 0.0 6.9e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PAZ_siRNAbind PF12212.3 EGF97088.1 - 0.043 13.4 0.0 1.6 8.3 0.0 2.8 3 0 0 3 3 3 0 Piwi/Argonaute/Zwille siRNA-binding domain MinC_C PF03775.11 EGF97088.1 - 0.11 12.1 7.3 17 5.0 0.2 3.7 2 2 1 3 3 3 0 Septum formation inhibitor MinC, C-terminal domain DHO_dh PF01180.16 EGF97088.1 - 1.7 7.5 4.9 1.7 7.5 0.3 2.2 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase EDR1 PF14381.1 EGF97089.1 - 0.057 12.9 0.3 0.11 11.9 0.1 1.5 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DEAD PF00270.24 EGF97090.1 - 7.6e-13 48.2 0.0 1.5e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGF97090.1 - 1.1e-08 34.8 0.0 2.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3505 PF12013.3 EGF97090.1 - 5e-08 33.1 2.3 1.9e-07 31.2 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) T4SS-DNA_transf PF02534.9 EGF97090.1 - 0.32 9.5 0.0 0.5 8.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Nuf2 PF03800.9 EGF97091.1 - 9.7e-14 51.5 0.0 1.1e-13 51.4 0.0 1.0 1 0 0 1 1 1 1 Nuf2 family XAP5 PF04921.9 EGF97099.1 - 0.0077 15.8 6.2 0.0091 15.5 4.3 1.0 1 0 0 1 1 1 1 XAP5, circadian clock regulator Trs65 PF12735.2 EGF97099.1 - 0.01 15.1 7.6 0.013 14.8 5.3 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 BSP_II PF05432.6 EGF97099.1 - 0.024 13.9 0.6 0.025 13.8 0.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) YmzC PF14157.1 EGF97099.1 - 0.065 13.0 4.6 0.15 11.8 0.1 2.4 2 1 0 2 2 2 0 YmzC-like protein DUF4551 PF15087.1 EGF97099.1 - 2.2 6.5 7.8 2.6 6.2 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MIF4G PF02854.14 EGF97102.1 - 6.3e-30 104.1 15.5 1e-29 103.4 10.7 1.3 1 1 0 1 1 1 1 MIF4G domain IBD PF10416.4 EGF97102.1 - 0.2 11.4 6.2 0.95 9.2 0.8 2.8 3 0 0 3 3 3 0 Transcription-initiator DNA-binding domain IBD DNA_pol_alpha_N PF12254.3 EGF97102.1 - 5.5 6.8 11.6 0.69 9.7 3.0 2.6 3 0 0 3 3 3 0 DNA polymerase alpha subunit p180 N terminal UBN2_3 PF14244.1 EGF97106.1 - 0.052 13.1 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type TRI9 PF08195.6 EGF97109.1 - 0.095 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 TRI9 protein Cript PF10235.4 EGF97109.1 - 0.16 12.3 3.2 0.38 11.1 2.2 1.7 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT PAP_central PF04928.12 EGF97110.1 - 1.3e-09 37.2 0.0 1.4e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Poly(A) polymerase central domain Alpha_kinase PF02816.13 EGF97115.1 - 3e-20 72.6 0.1 6.2e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 Alpha-kinase family zf-C4pol PF14260.1 EGF97115.1 - 4.5 7.3 7.7 2.5 8.1 0.5 3.0 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta TIMELESS PF04821.9 EGF97116.1 - 0.00081 18.7 0.2 0.0014 17.9 0.1 1.4 2 0 0 2 2 2 1 Timeless protein E7 PF00527.13 EGF97116.1 - 0.036 14.2 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 E7 protein, Early protein PSCyt3 PF07627.6 EGF97120.1 - 0.052 13.4 0.2 1.3 8.9 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) Glyco_hydro_10 PF00331.15 EGF97124.1 - 2.8e-72 243.4 0.0 3.5e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 EGF97124.1 - 0.0071 16.7 0.0 0.021 15.2 0.0 1.8 2 0 0 2 2 2 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 EGF97124.1 - 0.092 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase Rhodanese PF00581.15 EGF97125.1 - 6.9e-11 42.5 0.0 7e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain T2SM PF04612.7 EGF97125.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Brevenin PF03032.10 EGF97127.1 - 0.24 11.2 3.1 1 9.2 0.4 2.5 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family FAR1 PF03101.10 EGF97128.1 - 5.5e-06 26.8 0.2 1.3e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain PTR PF12789.2 EGF97129.1 - 0.12 12.2 0.0 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Phage tail repeat like POP1 PF06978.6 EGF97130.1 - 0.022 14.4 1.6 0.033 13.8 1.1 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Agro_virD5 PF04730.7 EGF97134.1 - 0.039 12.0 0.0 0.039 12.0 0.0 1.0 1 0 0 1 1 1 0 Agrobacterium VirD5 protein Aldo_ket_red PF00248.16 EGF97138.1 - 2.3e-38 131.6 0.0 2.8e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Spc97_Spc98 PF04130.8 EGF97139.1 - 0.025 12.9 0.3 0.025 12.9 0.2 1.6 2 0 0 2 2 2 0 Spc97 / Spc98 family PBP1_TM PF14812.1 EGF97139.1 - 3.8 7.8 9.9 13 6.1 6.9 1.9 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_18 PF13238.1 EGF97142.1 - 0.068 13.4 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Alpha_L_fucos PF01120.12 EGF97145.1 - 0.085 11.7 0.4 0.17 10.7 0.0 1.7 2 0 0 2 2 2 0 Alpha-L-fucosidase zf-CCHC PF00098.18 EGF97147.1 - 0.0028 17.5 2.3 0.0055 16.5 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 EGF97147.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HpaP PF09483.5 EGF97147.1 - 0.16 11.9 3.3 0.26 11.1 2.3 1.4 1 0 0 1 1 1 0 Type III secretion protein (HpaP) CRT10 PF08728.5 EGF97148.1 - 0.085 10.8 4.4 0.1 10.5 3.1 1.1 1 0 0 1 1 1 0 CRT10 zf-trcl PF13451.1 EGF97148.1 - 0.086 12.4 1.6 0.19 11.4 1.1 1.5 1 0 0 1 1 1 0 Probable zinc-binding domain DUF4259 PF14078.1 EGF97148.1 - 0.55 10.7 9.2 1.1 9.8 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) DUF4164 PF13747.1 EGF97148.1 - 0.67 10.1 4.5 5.4 7.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) BLOC1_2 PF10046.4 EGF97148.1 - 2.6 8.2 9.8 1.4 9.0 3.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SNF2_N PF00176.18 EGF97149.1 - 5.2e-45 153.5 3.3 5.8e-45 153.3 2.3 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGF97149.1 - 1.5e-08 34.2 0.0 1.8e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGF97149.1 - 0.00011 22.1 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGF97150.1 - 6.4e-14 51.5 0.0 1.1e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF566 PF04484.7 EGF97151.1 - 0.49 9.8 5.7 0.62 9.5 3.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) NPV_P10 PF05531.7 EGF97152.1 - 0.0026 17.9 4.7 0.0026 17.9 1.3 2.5 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein LPP PF04728.8 EGF97152.1 - 0.035 13.9 0.7 0.13 12.0 0.4 2.1 1 1 0 1 1 1 0 Lipoprotein leucine-zipper DUF4254 PF14063.1 EGF97152.1 - 0.038 13.6 1.4 0.074 12.6 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Syntaxin PF00804.20 EGF97152.1 - 0.31 11.2 8.6 0.22 11.6 1.6 2.5 2 1 0 2 2 2 0 Syntaxin GAS PF13851.1 EGF97152.1 - 0.34 10.0 6.4 0.11 11.6 2.3 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EGF97152.1 - 0.77 8.8 9.5 0.024 13.8 1.5 2.0 2 1 0 2 2 2 0 Reovirus sigma C capsid protein SlyX PF04102.7 EGF97152.1 - 1.6 9.1 7.5 2.1 8.7 0.2 2.7 1 1 1 2 2 2 0 SlyX COG2 PF06148.6 EGF97152.1 - 1.8 8.4 9.3 3.5 7.5 2.5 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mnd1 PF03962.10 EGF97152.1 - 4.3 6.9 9.8 0.44 10.1 2.5 2.1 2 0 0 2 2 2 0 Mnd1 family DUF3534 PF12053.3 EGF97153.1 - 0.017 14.9 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3534) ATP_transf PF09830.4 EGF97154.1 - 1.1e-17 63.5 0.0 2.1e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DASH_Ask1 PF08655.5 EGF97156.1 - 1.7e-23 82.2 0.0 2.7e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 DUF1183 PF06682.7 EGF97159.1 - 8.1e-15 55.2 0.2 5.1e-14 52.6 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) Ribophorin_I PF04597.9 EGF97161.1 - 1.6e-79 267.4 0.0 3.3e-79 266.4 0.0 1.5 1 1 0 1 1 1 1 Ribophorin I Snapin_Pallidin PF14712.1 EGF97163.1 - 0.019 15.2 1.7 0.019 15.2 1.2 2.5 1 1 1 2 2 2 0 Snapin/Pallidin ORF6C PF10552.4 EGF97163.1 - 0.073 12.8 0.6 0.19 11.4 0.4 1.7 1 0 0 1 1 1 0 ORF6C domain Syntaxin-6_N PF09177.6 EGF97163.1 - 0.11 12.8 2.5 0.33 11.3 1.7 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 EGF97163.1 - 0.18 11.5 2.8 0.31 10.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 EGF97163.1 - 0.45 8.8 5.8 0.68 8.2 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APC2 PF08672.6 EGF97167.1 - 0.11 12.7 5.2 0.14 12.4 0.5 3.5 4 0 0 4 4 4 0 Anaphase promoting complex (APC) subunit 2 AcylCoA_dehyd_C PF12186.3 EGF97167.1 - 0.2 11.5 4.5 5.3 6.9 0.5 2.8 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal SIP1 PF04938.7 EGF97172.1 - 4.5e-16 58.9 0.0 1.7e-15 57.0 0.0 1.8 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF4386 PF14329.1 EGF97172.1 - 0.025 14.0 0.1 0.047 13.1 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4386) RVT_3 PF13456.1 EGF97173.1 - 6e-07 29.1 0.0 2e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like DUF3226 PF11536.3 EGF97174.1 - 0.0071 15.8 2.4 0.011 15.1 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) IncA PF04156.9 EGF97174.1 - 0.055 13.0 4.0 0.11 12.0 2.8 1.6 1 0 0 1 1 1 0 IncA protein SURF6 PF04935.7 EGF97174.1 - 0.11 11.7 8.3 0.027 13.7 3.3 1.7 2 0 0 2 2 2 0 Surfeit locus protein 6 Bcr-Abl_Oligo PF09036.5 EGF97174.1 - 0.12 12.3 0.8 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF489 PF04356.7 EGF97174.1 - 0.39 10.2 4.3 0.53 9.8 2.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF489) DivIC PF04977.10 EGF97174.1 - 0.46 10.0 3.7 2.5 7.6 2.4 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF4260 PF14079.1 EGF97175.1 - 0.015 15.0 0.1 0.033 13.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) SART-1 PF03343.8 EGF97179.1 - 0.0055 15.1 8.1 0.0061 14.9 5.6 1.1 1 0 0 1 1 1 1 SART-1 family LNP1 PF15419.1 EGF97181.1 - 0.11 12.5 0.2 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 Daxx PF03344.10 EGF97182.1 - 2.9 6.2 18.9 3.3 6.0 13.1 1.0 1 0 0 1 1 1 0 Daxx Family Hom_end_hint PF05203.11 EGF97182.1 - 4.9 6.8 7.6 2.5 7.7 4.0 1.4 1 1 0 1 1 1 0 Hom_end-associated Hint Joubert PF15392.1 EGF97183.1 - 0.082 12.1 1.2 0.12 11.6 0.9 1.2 1 0 0 1 1 1 0 Joubert syndrome-associated ACP53EA PF06313.6 EGF97186.1 - 0.0086 15.9 0.3 0.016 15.1 0.2 1.4 1 0 0 1 1 1 1 Drosophila ACP53EA protein EFG_C PF00679.19 EGF97187.1 - 1.3e-08 34.6 0.0 1.3e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Elongation factor G C-terminus DUF4512 PF14975.1 EGF97188.1 - 0.15 12.9 1.7 1.8 9.4 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) SHOCT PF09851.4 EGF97188.1 - 0.36 10.3 2.1 9.6 5.8 0.1 2.4 2 0 0 2 2 2 0 Short C-terminal domain AAA_12 PF13087.1 EGF97190.1 - 4.6e-09 35.9 0.2 7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain FAD_binding_4 PF01565.18 EGF97191.1 - 4.2e-27 94.3 2.5 6.9e-27 93.6 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGF97191.1 - 1.8e-15 56.5 1.3 3.6e-15 55.6 0.9 1.5 1 0 0 1 1 1 1 Berberine and berberine like BBE PF08031.7 EGF97192.1 - 1.7e-15 56.6 1.4 3.5e-15 55.6 1.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EGF97192.1 - 0.0023 17.1 0.1 0.0026 16.9 0.1 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding SLT_2 PF13406.1 EGF97192.1 - 0.021 13.7 1.9 0.025 13.4 0.3 1.7 2 0 0 2 2 2 0 Transglycosylase SLT domain MMR1 PF08505.5 EGF97192.1 - 0.029 14.4 0.3 0.04 13.9 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FAD_binding_4 PF01565.18 EGF97193.1 - 2.9e-30 104.5 2.2 4.8e-30 103.8 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGF97193.1 - 4.5e-15 55.2 1.8 9.2e-15 54.2 1.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EGF97193.1 - 0.02 14.0 0.2 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Amidase02_C PF12123.3 EGF97193.1 - 0.038 13.6 0.1 0.96 9.1 0.0 3.2 2 1 1 3 3 3 0 N-acetylmuramoyl-l-alanine amidase Packaging_FI PF14000.1 EGF97195.1 - 0.13 12.5 4.9 1 9.5 0.0 2.8 3 0 0 3 3 3 0 DNA packaging protein FI Alpha_kinase PF02816.13 EGF97196.1 - 6.1e-05 22.7 0.1 0.00014 21.5 0.0 1.6 1 1 1 2 2 2 1 Alpha-kinase family Ank_2 PF12796.2 EGF97197.1 - 3.5e-10 40.0 0.0 6.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGF97197.1 - 2.7e-08 33.2 0.0 5.7e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 EGF97197.1 - 1.7e-07 31.2 0.0 4.4e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGF97197.1 - 3.9e-07 30.4 0.0 3e-06 27.5 0.0 2.2 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGF97197.1 - 5.7e-07 29.1 0.0 6.1e-06 25.9 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat Methyltransf_18 PF12847.2 EGF97197.1 - 0.031 14.8 0.0 0.081 13.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.20 EGF97199.1 - 1.6e-18 66.7 0.0 2.5e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF97199.1 - 3.3e-05 23.0 0.0 0.17 10.9 0.0 2.2 2 1 0 2 2 2 2 Protein tyrosine kinase RRN3 PF05327.6 EGF97199.1 - 0.071 11.2 0.1 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nefa_Nip30_N PF10187.4 EGF97200.1 - 0.13 12.4 0.5 3.3 7.9 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 SSP160 PF06933.6 EGF97200.1 - 0.17 9.8 7.2 0.27 9.1 5.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 LRR_4 PF12799.2 EGF97201.1 - 8.9e-29 98.6 50.2 3.2e-05 23.4 0.1 9.8 7 2 2 10 10 10 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGF97201.1 - 2.8e-16 57.0 53.8 0.051 13.6 0.4 15.1 11 2 3 14 14 14 8 Leucine Rich Repeat LRR_8 PF13855.1 EGF97201.1 - 3.9e-15 55.3 50.8 0.00021 20.9 3.4 8.6 5 3 4 9 9 9 8 Leucine rich repeat LRR_6 PF13516.1 EGF97201.1 - 7.8e-11 40.8 47.1 0.023 14.7 0.1 13.0 13 0 0 13 13 13 4 Leucine Rich repeat LRR_7 PF13504.1 EGF97201.1 - 2.3e-07 29.8 49.9 0.48 10.8 0.0 13.7 14 1 0 14 14 14 4 Leucine rich repeat DUF445 PF04286.7 EGF97201.1 - 0.072 12.6 3.7 0.063 12.8 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF445) HMG_box PF00505.14 EGF97203.1 - 0.0021 18.2 0.1 0.0047 17.1 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGF97203.1 - 0.013 15.8 0.1 0.035 14.4 0.1 1.7 1 0 0 1 1 1 0 HMG-box domain zf-CCHC_3 PF13917.1 EGF97204.1 - 0.00019 21.0 0.6 0.00019 21.0 0.4 1.8 2 0 0 2 2 2 1 Zinc knuckle SET PF00856.23 EGF97205.1 - 3.1e-05 24.3 0.0 4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 SET domain Dynamin_N PF00350.18 EGF97208.1 - 1.7e-05 24.6 0.0 2.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Dynamin family Effector_1 PF04518.7 EGF97212.1 - 0.082 11.8 5.3 0.11 11.5 3.7 1.1 1 0 0 1 1 1 0 Effector from type III secretion system DUF1423 PF07227.6 EGF97212.1 - 0.16 10.5 7.5 0.21 10.1 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DUF3043 PF11241.3 EGF97212.1 - 0.92 9.0 8.5 1.4 8.4 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Atg14 PF10186.4 EGF97212.1 - 1.7 7.5 8.4 2.2 7.1 5.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RNase_H2-Ydr279 PF09468.5 EGF97212.1 - 4.6 6.3 10.3 5.8 6.0 7.2 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Polyketide_cyc PF03364.15 EGF97213.1 - 3.2e-17 62.7 0.0 3.8e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EGF97214.1 - 8.2e-16 58.1 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF500 PF04366.7 EGF97215.1 - 3.6e-25 87.8 0.1 6.5e-25 87.0 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) DUF812 PF05667.6 EGF97219.1 - 0.0023 16.5 0.5 0.0023 16.5 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF812) LOH1CR12 PF10158.4 EGF97219.1 - 0.011 15.4 0.6 0.027 14.2 0.4 1.6 1 0 0 1 1 1 0 Tumour suppressor protein BLOC1_2 PF10046.4 EGF97219.1 - 0.057 13.5 2.9 0.065 13.3 0.8 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4511 PF14974.1 EGF97219.1 - 0.074 12.7 1.3 0.28 10.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4511) NPV_P10 PF05531.7 EGF97219.1 - 0.093 12.9 1.1 2.7 8.3 0.0 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Noelin-1 PF12308.3 EGF97219.1 - 0.16 11.8 1.4 0.38 10.5 0.6 1.9 1 1 1 2 2 2 0 Neurogenesis glycoprotein STAT_alpha PF01017.15 EGF97219.1 - 0.27 10.9 4.5 0.7 9.5 3.1 1.6 1 0 0 1 1 1 0 STAT protein, all-alpha domain GAS PF13851.1 EGF97219.1 - 0.37 9.9 6.7 0.37 9.9 3.8 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IQ-like PF15157.1 EGF97219.1 - 0.54 10.4 3.2 0.48 10.6 0.4 2.2 2 0 0 2 2 2 0 IQ-like IncA PF04156.9 EGF97219.1 - 2.6 7.5 5.7 5.1 6.6 4.0 1.4 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 EGF97219.1 - 2.9 6.4 10.2 0.28 9.8 4.0 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.4 EGF97220.1 - 0.015 15.3 0.8 0.03 14.3 0.5 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TPR_9 PF13371.1 EGF97220.1 - 0.06 13.2 0.1 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat G-gamma PF00631.17 EGF97222.1 - 0.24 11.1 1.5 0.86 9.3 1.0 1.9 1 1 0 1 1 1 0 GGL domain Endonuc_BglI PF14562.1 EGF97225.1 - 0.059 12.2 0.1 0.11 11.2 0.0 1.4 2 0 0 2 2 2 0 Restriction endonuclease BglI DUF939_C PF11728.3 EGF97230.1 - 0.09 12.5 0.7 0.14 12.0 0.1 1.5 2 0 0 2 2 2 0 DUF939 C-terminal domain MFS_1 PF07690.11 EGF97233.1 - 1.9e-19 69.6 15.4 6.9e-19 67.7 7.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGF97233.1 - 2.5e-06 26.3 8.2 2.5e-06 26.3 5.7 1.7 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EGF97233.1 - 0.0052 14.9 1.5 0.0052 14.9 1.1 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector PAN_4 PF14295.1 EGF97236.1 - 7.8 6.2 7.3 0.42 10.3 0.8 2.0 2 1 0 2 2 2 0 PAN domain PRCC PF10253.4 EGF97237.1 - 0.01 16.5 0.3 0.01 16.5 0.2 2.6 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2670 PF10875.3 EGF97237.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) Inh PF02974.9 EGF97238.1 - 0.047 13.2 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Protease inhibitor Inh UDG PF03167.14 EGF97240.1 - 0.042 13.3 0.0 9.6 5.6 0.0 2.8 3 0 0 3 3 3 0 Uracil DNA glycosylase superfamily Uds1 PF15456.1 EGF97241.1 - 0.029 14.3 0.1 0.062 13.3 0.1 1.6 1 1 0 1 1 1 0 Up-regulated During Septation LRR_4 PF12799.2 EGF97242.1 - 0.2 11.3 8.6 28 4.4 0.0 4.5 2 2 3 5 5 5 0 Leucine Rich repeats (2 copies) DUF3704 PF12488.3 EGF97252.1 - 0.02 14.5 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) RinB PF06116.7 EGF97253.1 - 2.9 7.5 7.4 0.44 10.1 2.0 1.9 1 1 1 2 2 2 0 Transcriptional activator RinB TFIIF_alpha PF05793.7 EGF97254.1 - 8.5 4.6 12.7 9.3 4.4 8.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bestrophin PF01062.16 EGF97256.1 - 1.8e-45 155.1 2.5 6.7e-27 94.1 0.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Zn_clus PF00172.13 EGF97259.1 - 1e-05 25.3 8.3 2.8e-05 23.9 5.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L4 PF00573.17 EGF97261.1 - 2.6e-46 157.4 0.0 9.2e-46 155.6 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family dCMP_cyt_deam_1 PF00383.17 EGF97265.1 - 7.6e-25 86.5 0.5 1.1e-24 86.0 0.4 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 EGF97265.1 - 0.0057 16.3 0.1 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase Golgin_A5 PF09787.4 EGF97266.1 - 0.3 9.5 5.0 0.36 9.3 2.4 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF342 PF03961.8 EGF97267.1 - 0.0061 15.0 3.1 0.0069 14.8 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DUF2951 PF11166.3 EGF97267.1 - 1.1 9.1 6.1 32 4.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) DUF745 PF05335.8 EGF97267.1 - 1.5 8.2 3.8 0.38 10.2 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Zn_clus PF00172.13 EGF97268.1 - 3.9e-05 23.4 2.8 5.5e-05 22.9 2.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.4 EGF97268.1 - 0.15 10.7 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein KIF1B PF12423.3 EGF97268.1 - 0.16 11.9 0.4 0.44 10.6 0.3 1.7 1 0 0 1 1 1 0 Kinesin protein 1B TSGA13 PF14994.1 EGF97269.1 - 0.0069 15.5 0.1 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Testis-specific gene 13 protein HeH PF12949.2 EGF97269.1 - 0.12 11.9 0.1 1.8 8.2 0.0 2.6 3 0 0 3 3 3 0 HeH/LEM domain NTF2 PF02136.15 EGF97274.1 - 0.067 13.5 0.1 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DUF3499 PF12005.3 EGF97279.1 - 0.071 13.2 0.3 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) SUD-M PF11633.3 EGF97279.1 - 0.1 11.8 0.3 3.4 6.9 0.0 2.6 1 1 1 3 3 3 0 Single-stranded poly(A) binding domain FYRN PF05964.9 EGF97279.1 - 0.17 11.3 0.3 5.9 6.4 0.0 3.1 2 2 1 3 3 3 0 F/Y-rich N-terminus DUF2665 PF11654.3 EGF97279.1 - 0.32 10.5 2.6 12 5.5 0.0 3.4 2 1 3 5 5 5 0 Protein of unknown function (DUF2665) Prefoldin_2 PF01920.15 EGF97280.1 - 0.041 13.6 0.8 0.041 13.6 0.5 2.9 3 1 1 4 4 4 0 Prefoldin subunit FemAB PF02388.11 EGF97280.1 - 0.096 11.3 0.3 0.27 9.8 0.0 1.8 2 0 0 2 2 2 0 FemAB family Helicase_C PF00271.26 EGF97283.1 - 0.0048 16.7 0.0 0.0094 15.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Topo_C_assoc PF14370.1 EGF97284.1 - 0.02 14.5 0.6 0.038 13.6 0.4 1.4 1 0 0 1 1 1 0 C-terminal topoisomerase domain Thioredoxin_5 PF13743.1 EGF97286.1 - 0.01 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin DUF3474 PF11960.3 EGF97287.1 - 0.45 10.5 6.0 0.15 12.1 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3474) STE3 PF02076.10 EGF97290.1 - 1.6e-57 194.7 13.4 1.9e-57 194.5 9.3 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF4010 PF13194.1 EGF97290.1 - 0.058 12.6 1.0 0.11 11.7 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Ribosomal_L20 PF00453.13 EGF97291.1 - 0.082 12.8 0.0 8.9 6.2 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein L20 LEDGF PF11467.3 EGF97297.1 - 0.079 12.6 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) SlyX PF04102.7 EGF97298.1 - 1.5 9.2 5.6 0.35 11.2 0.6 2.4 3 0 0 3 3 3 0 SlyX Omptin PF01278.15 EGF97302.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 Omptin family Remorin_N PF03766.8 EGF97304.1 - 0.34 10.7 4.1 0.79 9.5 2.9 1.7 1 0 0 1 1 1 0 Remorin, N-terminal region PAT1 PF09770.4 EGF97305.1 - 6 4.9 23.9 7.2 4.7 16.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GCM PF03615.10 EGF97309.1 - 0.0011 18.5 2.2 0.0021 17.6 0.5 2.0 2 0 0 2 2 2 1 GCM motif protein DUF788 PF05620.6 EGF97310.1 - 0.43 10.4 1.7 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Myb_DNA-bind_6 PF13921.1 EGF97312.1 - 0.00076 19.5 0.4 0.04 14.0 0.0 3.4 2 1 1 3 3 3 1 Myb-like DNA-binding domain DUF236 PF03057.9 EGF97313.1 - 0.1 12.5 0.2 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function FKBP_N PF01346.13 EGF97321.1 - 8.6 6.4 7.1 2.3 8.2 0.2 2.1 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Atg14 PF10186.4 EGF97324.1 - 0.23 10.3 3.5 0.25 10.2 2.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SRP-alpha_N PF04086.8 EGF97324.1 - 4.4 6.5 12.7 4.5 6.5 8.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PAPA-1 PF04795.7 EGF97324.1 - 8.8 7.1 19.8 14 6.4 13.7 1.4 1 0 0 1 1 1 0 PAPA-1-like conserved region MMR_HSR1 PF01926.18 EGF97325.1 - 7.8e-05 22.6 0.0 8.3e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SAP PF02037.22 EGF97326.1 - 0.02 14.3 0.1 0.044 13.3 0.1 1.6 1 0 0 1 1 1 0 SAP domain zf-RING_2 PF13639.1 EGF97327.1 - 4.8e-12 45.5 7.9 4.8e-12 45.5 5.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EGF97327.1 - 1.3e-07 31.5 6.3 1.3e-07 31.5 4.3 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGF97327.1 - 2.5e-07 30.2 9.3 5.2e-07 29.2 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGF97327.1 - 4e-07 29.9 9.9 4e-07 29.9 6.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGF97327.1 - 2.4e-05 23.9 5.7 4.4e-05 23.0 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGF97327.1 - 6.9e-05 22.4 8.0 0.00014 21.4 5.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Atracotoxin PF05353.6 EGF97327.1 - 0.016 15.0 0.5 0.031 14.0 0.3 1.5 1 0 0 1 1 1 0 Delta Atracotoxin Apt1 PF10351.4 EGF97327.1 - 0.036 12.9 4.7 0.056 12.3 3.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-HC5HC2H_2 PF13832.1 EGF97327.1 - 0.15 12.0 3.0 0.32 10.9 2.1 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 EGF97327.1 - 0.29 10.8 5.2 0.74 9.5 3.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EGF97327.1 - 0.3 11.0 4.9 0.94 9.4 3.4 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EGF97327.1 - 0.45 10.5 5.5 1.2 9.2 3.8 1.7 1 1 0 1 1 1 0 RING-variant domain Pex14_N PF04695.8 EGF97327.1 - 1 9.4 6.4 1.5 8.9 3.4 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Corona_nucleoca PF00937.13 EGF97327.1 - 2.3 7.0 10.8 3.2 6.6 7.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4614 PF15391.1 EGF97327.1 - 3.2 7.4 15.0 4.4 7.0 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) zf-C3HC4_4 PF15227.1 EGF97327.1 - 4.3 7.2 9.2 57 3.7 6.5 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING AF-4 PF05110.8 EGF97327.1 - 6.8 4.4 23.1 8.5 4.0 16.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein zf-Apc11 PF12861.2 EGF97327.1 - 8.1 6.3 14.2 0.06 13.1 3.7 2.0 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Macoilin PF09726.4 EGF97327.1 - 9.2 4.4 10.3 12 4.0 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein SEA PF01390.15 EGF97329.1 - 0.051 13.2 0.9 0.62 9.7 0.1 2.7 3 0 0 3 3 3 0 SEA domain GCM PF03615.10 EGF97334.1 - 0.0031 17.1 2.7 0.0071 15.9 1.9 1.5 1 0 0 1 1 1 1 GCM motif protein Med31 PF05669.7 EGF97338.1 - 1.6e-28 98.3 1.9 1.9e-28 98.1 1.3 1.1 1 0 0 1 1 1 1 SOH1 Sugarporin_N PF11471.3 EGF97339.1 - 0.00073 19.1 1.4 0.002 17.7 1.0 1.7 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension Snapin_Pallidin PF14712.1 EGF97339.1 - 0.022 15.0 6.5 2 8.7 0.2 2.7 1 1 1 2 2 2 0 Snapin/Pallidin DUF342 PF03961.8 EGF97339.1 - 0.14 10.5 7.9 0.0099 14.3 2.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) GTPase_Cys_C PF12631.2 EGF97339.1 - 1 9.8 3.3 2.2 8.7 0.2 2.5 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE YlqD PF11068.3 EGF97339.1 - 3.6 7.6 14.7 0.69 9.9 6.7 2.0 2 0 0 2 2 2 0 YlqD protein Lzipper-MIP1 PF14389.1 EGF97344.1 - 0.006 16.6 0.3 0.029 14.4 0.0 2.2 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 DUF605 PF04652.11 EGF97346.1 - 4.4 6.5 10.5 6.6 6.0 7.3 1.2 1 0 0 1 1 1 0 Vta1 like PHTB1_N PF14727.1 EGF97347.1 - 0.069 12.0 0.1 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 PTHB1 N-terminus LCM PF04072.9 EGF97347.1 - 0.14 11.6 0.7 1.5 8.3 0.1 2.3 2 1 1 3 3 3 0 Leucine carboxyl methyltransferase Rho_Binding PF08912.6 EGF97347.1 - 0.29 11.4 2.8 0.21 11.8 0.4 1.8 2 0 0 2 2 2 0 Rho Binding Baculo_LEF-3 PF05847.6 EGF97348.1 - 0.091 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) PCNA_C PF02747.10 EGF97349.1 - 1.3e-46 157.7 0.1 1.7e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 EGF97349.1 - 2.8e-05 23.0 0.3 3.5e-05 22.7 0.2 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF188 PF02639.9 EGF97350.1 - 0.042 13.3 1.1 0.077 12.4 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 DUF1875 PF08961.5 EGF97351.1 - 0.054 12.8 3.9 0.21 10.9 2.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1875) DltD_M PF04918.7 EGF97352.1 - 0.86 9.7 7.7 1.1 9.4 4.5 1.6 1 1 1 2 2 2 0 DltD central region Spore_coat_CotO PF14153.1 EGF97352.1 - 5.9 6.2 12.4 9.9 5.5 8.6 1.3 1 0 0 1 1 1 0 Spore coat protein CotO PPP1R35_C PF15503.1 EGF97353.1 - 0.14 11.6 0.0 0.14 11.6 0.0 2.4 3 0 0 3 3 3 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Clathrin_bdg PF15045.1 EGF97355.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Nrf1_activ_bdg PF10492.4 EGF97356.1 - 0.089 13.2 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Nrf1 activator activation site binding domain SH3_1 PF00018.23 EGF97357.1 - 0.00039 19.7 0.0 0.0005 19.4 0.0 1.1 1 0 0 1 1 1 1 SH3 domain Amidase PF01425.16 EGF97358.1 - 2e-40 139.0 0.0 3.4e-20 72.3 0.0 2.0 1 1 1 2 2 2 2 Amidase DUF605 PF04652.11 EGF97361.1 - 3.6 6.8 9.5 4.4 6.6 6.6 1.1 1 0 0 1 1 1 0 Vta1 like SUZ PF12752.2 EGF97363.1 - 0.1 13.1 1.1 0.27 11.8 0.8 1.7 1 0 0 1 1 1 0 SUZ domain PH PF00169.24 EGF97364.1 - 0.089 13.0 0.0 0.21 11.8 0.0 1.6 2 0 0 2 2 2 0 PH domain Prothymosin PF03247.9 EGF97367.1 - 0.0083 16.2 13.7 0.0083 16.2 9.5 3.2 3 0 0 3 3 3 1 Prothymosin/parathymosin family DUF3530 PF12048.3 EGF97367.1 - 0.042 12.8 3.7 0.074 12.0 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) GatB_N PF02934.10 EGF97368.1 - 3.3e-14 52.4 0.2 1.6e-06 27.2 0.1 2.0 1 1 1 2 2 2 2 GatB/GatE catalytic domain Polysacc_deac_1 PF01522.16 EGF97370.1 - 7.9e-28 96.5 0.0 1.2e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase SPDY PF03771.11 EGF97370.1 - 0.0039 16.6 0.6 0.14 11.6 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF317) Glyco_hydro_57 PF03065.10 EGF97370.1 - 0.011 14.7 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF2823 PF11034.3 EGF97372.1 - 9.3e-12 44.9 3.2 1.2e-11 44.5 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) Zn_clus PF00172.13 EGF97373.1 - 8.3e-07 28.8 5.1 1.6e-06 27.9 3.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBR PF01485.16 EGF97381.1 - 0.027 14.3 1.4 0.1 12.4 1.0 1.8 1 1 0 1 1 1 0 IBR domain zf-H2C2_2 PF13465.1 EGF97381.1 - 0.14 12.4 0.4 0.14 12.4 0.3 2.6 3 0 0 3 3 3 0 Zinc-finger double domain P5CR_dimer PF14748.1 EGF97382.1 - 5.5e-38 129.2 3.6 8e-37 125.5 1.2 2.3 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EGF97382.1 - 1.3e-11 44.7 0.2 1.8e-08 34.6 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EGF97382.1 - 0.21 11.0 1.8 0.94 8.9 0.0 2.3 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA AMP-binding PF00501.23 EGF97383.1 - 4.4e-25 87.9 0.0 3.7e-23 81.6 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme GBP_PSP PF02425.10 EGF97383.1 - 0.018 14.5 0.2 0.063 12.8 0.1 1.9 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide DUF1732 PF08340.6 EGF97384.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) Exo_endo_phos PF03372.18 EGF97385.1 - 5.8e-12 46.0 0.0 7.7e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family S4 PF01479.20 EGF97386.1 - 4.2e-13 48.5 4.1 2.1e-12 46.2 1.0 2.5 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.14 EGF97386.1 - 1.8e-10 41.0 0.6 1.8e-10 41.0 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Alpha_kinase PF02816.13 EGF97388.1 - 5.6e-09 35.9 0.1 6.9e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family NST1 PF13945.1 EGF97390.1 - 4.4e-45 154.1 0.0 4.4e-45 154.1 0.0 5.9 5 1 1 6 6 6 3 Salt tolerance down-regulator PfkB PF00294.19 EGF97392.1 - 1.5e-16 60.3 0.0 2.3e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EGF97392.1 - 0.00031 20.0 0.0 0.00043 19.5 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DAO PF01266.19 EGF97394.1 - 6e-14 51.7 0.0 1.1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase EF-hand_7 PF13499.1 EGF97394.1 - 9.6e-09 35.2 0.0 5.3e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGF97394.1 - 2e-05 23.5 0.0 0.00061 18.9 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EGF97394.1 - 0.00049 19.7 0.1 0.01 15.6 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EGF97394.1 - 0.01 15.4 0.0 0.056 13.0 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 EGF97394.1 - 0.011 15.0 0.2 0.027 13.8 0.1 1.7 1 0 0 1 1 1 0 EF hand PGDYG PF14083.1 EGF97394.1 - 0.037 14.4 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 PGDYG protein DUF4368 PF14287.1 EGF97395.1 - 0.11 12.2 0.8 0.27 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) zf-CSL PF05207.8 EGF97396.1 - 1.5e-16 59.6 1.2 3.2e-16 58.5 0.8 1.6 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EGF97396.1 - 5.9e-16 57.9 0.3 8.7e-16 57.4 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain Lum_binding PF00677.12 EGF97396.1 - 0.029 14.2 0.2 0.068 13.0 0.1 1.6 1 1 0 1 1 1 0 Lumazine binding domain RA PF00788.18 EGF97396.1 - 0.11 12.9 0.1 0.27 11.7 0.1 1.9 1 1 0 1 1 1 0 Ras association (RalGDS/AF-6) domain DUF702 PF05142.7 EGF97397.1 - 0.021 15.0 2.8 0.025 14.7 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) OmpH PF03938.9 EGF97397.1 - 0.58 10.0 10.1 0.69 9.8 7.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4164 PF13747.1 EGF97397.1 - 0.75 9.9 11.2 0.13 12.3 3.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Romo1 PF10247.4 EGF97398.1 - 2.8e-20 72.2 11.1 4.1e-20 71.7 7.7 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 RibD_C PF01872.12 EGF97399.1 - 6.9e-30 104.1 0.0 8e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Aldolase PF01081.14 EGF97399.1 - 0.074 12.2 0.0 5 6.2 0.0 2.2 2 0 0 2 2 2 0 KDPG and KHG aldolase DUF4214 PF13946.1 EGF97399.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) Apolipoprotein PF01442.13 EGF97405.1 - 5.2e-05 22.8 0.1 0.00019 20.9 0.0 1.9 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 EGF97405.1 - 0.00034 20.4 4.4 0.00034 20.4 3.1 2.1 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.6 EGF97405.1 - 0.0057 15.8 1.8 0.24 10.5 0.7 2.2 2 0 0 2 2 2 1 SF-assemblin/beta giardin Use1 PF09753.4 EGF97405.1 - 0.014 14.7 1.2 0.03 13.7 0.8 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 WXG100 PF06013.7 EGF97405.1 - 0.027 14.4 0.6 1.1 9.3 0.3 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG ABC_transp_aux PF09822.4 EGF97405.1 - 0.028 13.8 0.1 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC-type uncharacterized transport system CorA PF01544.13 EGF97405.1 - 0.093 11.7 0.6 1.1 8.1 0.3 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein ApoLp-III PF07464.6 EGF97405.1 - 0.13 12.2 3.0 0.51 10.3 1.0 2.3 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Syntaxin PF00804.20 EGF97405.1 - 0.4 10.8 7.7 0.97 9.6 3.1 2.9 2 2 0 2 2 2 0 Syntaxin LPP PF04728.8 EGF97405.1 - 1 9.2 7.5 24 4.7 0.2 3.3 2 1 1 3 3 3 0 Lipoprotein leucine-zipper FlaC_arch PF05377.6 EGF97405.1 - 1.3 8.9 4.1 17 5.4 2.8 2.7 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.8 EGF97405.1 - 1.6 8.1 3.8 2.5 7.4 1.0 2.1 2 1 0 2 2 2 0 fzo-like conserved region DUF1664 PF07889.7 EGF97405.1 - 2.2 8.1 5.8 1.3 8.8 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-Q PF13094.1 EGF97405.1 - 2.7 7.9 6.0 2.1 8.3 2.0 2.5 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit F-box-like PF12937.2 EGF97406.1 - 0.00042 19.9 2.2 0.00048 19.7 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGF97406.1 - 0.0079 15.8 0.0 0.095 12.3 0.0 2.5 2 1 0 2 2 2 1 F-box domain I_LWEQ PF01608.12 EGF97408.1 - 0.028 14.3 2.5 0.036 14.0 1.7 1.3 1 0 0 1 1 1 0 I/LWEQ domain UPF0150 PF03681.10 EGF97408.1 - 0.056 13.0 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) FimP PF09766.4 EGF97408.1 - 0.065 12.2 3.3 0.075 12.0 2.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein FLO_LFY PF01698.11 EGF97410.1 - 2 7.1 23.9 0.11 11.2 8.6 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein Nup54 PF13874.1 EGF97413.1 - 0.074 12.7 2.4 0.2 11.3 1.6 1.8 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Mt_ATP-synt_D PF05873.7 EGF97413.1 - 0.45 10.1 3.6 0.25 10.9 0.8 1.8 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF16 PF01519.11 EGF97413.1 - 4.9 7.4 7.1 7.9 6.7 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.7 EGF97414.1 - 0.1 12.9 0.3 0.36 11.2 0.1 2.1 2 0 0 2 2 2 0 SlyX IncA PF04156.9 EGF97418.1 - 0.07 12.7 2.7 0.11 12.1 1.9 1.4 1 0 0 1 1 1 0 IncA protein Peptidase_M3_N PF08439.5 EGF97418.1 - 0.16 11.9 2.8 0.28 11.2 1.2 2.0 1 1 1 2 2 2 0 Oligopeptidase F PRP3 PF08572.5 EGF97418.1 - 0.82 9.0 5.8 1.3 8.3 3.9 1.4 1 1 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Glyco_hydro_42 PF02449.10 EGF97419.1 - 0.017 14.2 0.1 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Beta-galactosidase CENP-Q PF13094.1 EGF97420.1 - 0.27 11.2 15.8 0.25 11.3 1.7 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Dynamin_N PF00350.18 EGF97420.1 - 1.1 9.0 3.9 0.33 10.7 0.1 2.1 3 0 0 3 3 3 0 Dynamin family AMP-binding PF00501.23 EGF97424.1 - 2.3e-29 102.0 0.0 2.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Borrelia_P83 PF05262.6 EGF97425.1 - 1.3 7.2 7.6 1.8 6.7 5.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1840 PF08895.6 EGF97425.1 - 1.7 8.6 6.7 6 6.9 4.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) LEDGF PF11467.3 EGF97433.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) RHD3 PF05879.7 EGF97434.1 - 2.8e-16 58.6 1.0 3.8e-16 58.1 0.7 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 EGF97434.1 - 3.5e-06 26.9 0.0 5.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EGF97434.1 - 0.00056 20.3 0.0 0.00083 19.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGF97434.1 - 0.00058 19.7 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EGF97434.1 - 0.0012 18.8 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGF97434.1 - 0.0055 16.2 0.1 0.009 15.5 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EGF97434.1 - 0.017 15.0 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGF97434.1 - 0.044 13.4 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 EGF97434.1 - 0.05 12.7 0.0 0.051 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 EGF97434.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 EGF97434.1 - 0.075 12.0 0.1 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Septin ABC_tran PF00005.22 EGF97434.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Melibiase PF02065.13 EGF97435.1 - 0.00074 18.3 0.1 0.0011 17.6 0.1 1.2 1 0 0 1 1 1 1 Melibiase zf-C3HC4_3 PF13920.1 EGF97437.1 - 9.6e-07 28.3 1.5 1.3e-06 27.9 1.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGF97437.1 - 1.2e-06 28.4 3.8 2e-06 27.6 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGF97437.1 - 1.8e-06 27.6 3.7 3e-06 26.9 2.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGF97437.1 - 1e-05 25.1 3.2 1.8e-05 24.2 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGF97437.1 - 1.4e-05 24.8 2.5 2.5e-05 24.0 1.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGF97437.1 - 3.9e-05 23.2 3.1 6.1e-05 22.6 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain FYVE PF01363.16 EGF97437.1 - 0.0006 19.6 1.1 0.00098 18.9 0.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_UBOX PF13445.1 EGF97437.1 - 0.0015 18.1 1.3 0.0015 18.1 0.9 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EGF97437.1 - 0.0037 17.0 1.4 0.01 15.6 1.0 1.7 1 1 0 1 1 1 1 zf-RING of BARD1-type protein Rtf2 PF04641.7 EGF97437.1 - 0.0072 15.5 0.1 0.0098 15.1 0.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_4 PF14570.1 EGF97437.1 - 0.024 14.2 1.4 0.034 13.7 1.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EGF97437.1 - 0.026 14.5 2.0 0.051 13.6 1.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 EGF97437.1 - 0.032 13.7 2.7 0.055 12.9 1.9 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EGF97437.1 - 0.073 12.5 1.2 0.13 11.7 0.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.9 EGF97437.1 - 0.21 11.0 0.1 0.21 11.0 0.1 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif IBR PF01485.16 EGF97437.1 - 2.8 7.8 6.1 4.1 7.3 1.2 2.2 1 1 1 2 2 2 0 IBR domain DltD_M PF04918.7 EGF97439.1 - 0.011 15.9 1.0 0.016 15.4 0.7 1.2 1 0 0 1 1 1 0 DltD central region HypA PF01155.14 EGF97440.1 - 0.045 13.4 0.2 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Pkinase PF00069.20 EGF97441.1 - 0.0019 17.4 0.0 0.0022 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF2456 PF10445.4 EGF97443.1 - 1.2e-17 63.6 3.1 2.3e-17 62.6 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) zf-C2H2 PF00096.21 EGF97444.1 - 0.0099 16.1 0.7 0.041 14.2 0.5 2.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGF97444.1 - 0.032 14.5 1.1 0.032 14.5 0.8 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger DEAD PF00270.24 EGF97445.1 - 1.5e-16 60.3 0.0 4.7e-16 58.7 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase RAP1 PF07218.6 EGF97447.1 - 1.7 6.6 3.7 2.3 6.2 2.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cyt-b5 PF00173.23 EGF97449.1 - 1.5e-19 69.5 0.0 1.7e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2183 PF09949.4 EGF97449.1 - 0.14 12.1 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Metallophos PF00149.23 EGF97450.1 - 6.3e-07 28.9 0.1 1.3e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGF97450.1 - 0.043 13.6 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain McyA_C PF12593.3 EGF97451.1 - 0.06 13.1 3.7 0.95 9.2 0.1 2.8 1 1 1 2 2 2 0 Microcystin synthetase C terminal Asn_synthase PF00733.16 EGF97459.1 - 3.5e-49 167.5 0.0 5.2e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGF97459.1 - 1e-09 38.2 0.0 2.7e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGF97459.1 - 3.9e-06 26.8 0.0 7.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EGF97459.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein T2SE PF00437.15 EGF97460.1 - 6.7e-05 21.9 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EGF97460.1 - 0.004 17.3 0.2 0.014 15.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EGF97460.1 - 0.0083 15.5 0.1 0.042 13.3 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.17 EGF97460.1 - 0.025 13.4 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 EGF97460.1 - 0.027 13.5 2.4 0.54 9.3 0.0 2.6 2 1 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 EGF97460.1 - 0.028 14.0 0.1 0.053 13.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGF97460.1 - 0.028 14.1 0.3 0.059 13.1 0.2 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EGF97460.1 - 0.049 13.0 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGF97460.1 - 0.056 13.7 1.1 0.48 10.7 0.1 2.4 1 1 1 2 2 2 0 ABC transporter Mannitol_dh PF01232.18 EGF97460.1 - 0.066 13.1 0.3 0.25 11.2 0.0 2.0 2 1 1 3 3 3 0 Mannitol dehydrogenase Rossmann domain HD_3 PF13023.1 EGF97460.1 - 0.095 12.4 0.3 0.58 9.8 0.1 2.1 2 0 0 2 2 2 0 HD domain FtsK_SpoIIIE PF01580.13 EGF97460.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EGF97460.1 - 0.11 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 EGF97460.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.1 EGF97460.1 - 3.7 7.8 6.0 1.8 8.8 0.2 2.2 1 1 1 2 2 2 0 AAA domain MSC PF09402.5 EGF97464.1 - 0.06 12.0 1.8 0.42 9.2 0.2 2.0 1 1 0 2 2 2 0 Man1-Src1p-C-terminal domain WD40 PF00400.27 EGF97466.1 - 2.8e-11 42.8 1.3 0.00017 21.3 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Alpha_kinase PF02816.13 EGF97468.1 - 1.5e-05 24.7 0.2 2e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family M-inducer_phosp PF06617.8 EGF97469.1 - 0.01 14.9 0.9 0.38 9.7 0.2 2.0 1 1 1 2 2 2 0 M-phase inducer phosphatase RVP PF00077.15 EGF97469.1 - 0.078 12.9 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease LRR_4 PF12799.2 EGF97472.1 - 0.098 12.3 0.1 0.67 9.6 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF2306 PF10067.4 EGF97473.1 - 0.15 12.1 0.3 0.31 11.1 0.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) Paramyxo_NS_C PF02725.9 EGF97474.1 - 0.025 14.1 1.2 0.035 13.7 0.8 1.2 1 0 0 1 1 1 0 Non-structural protein C HATPase_c_2 PF13581.1 EGF97475.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain MaoC_dehydratas PF01575.14 EGF97477.1 - 4.5e-11 42.1 0.0 7.6e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EGF97477.1 - 0.0012 18.5 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Inhibitor_I53 PF11714.3 EGF97480.1 - 0.11 12.4 0.5 2.9 7.9 0.3 2.3 2 1 0 2 2 2 0 Thrombin inhibitor Madanin ETF_alpha PF00766.14 EGF97481.1 - 1.9e-31 107.4 0.2 5e-31 106.1 0.0 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EGF97481.1 - 0.022 14.4 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein domain DUF883 PF05957.8 EGF97482.1 - 1.4e-05 25.3 47.7 0.073 13.4 4.2 5.3 2 2 3 5 5 5 5 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EGF97482.1 - 0.028 14.7 51.7 6.2 7.2 7.8 6.2 1 1 1 2 2 2 0 YtxH-like protein Apolipoprotein PF01442.13 EGF97482.1 - 0.096 12.1 23.7 5.2 6.5 16.5 2.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain LEA_4 PF02987.11 EGF97482.1 - 1.7 8.5 76.5 0.079 12.8 5.9 7.7 4 2 3 7 7 7 0 Late embryogenesis abundant protein Abhydrolase_6 PF12697.2 EGF97483.1 - 0.00025 20.9 0.0 0.00027 20.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGF97483.1 - 0.0023 17.7 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGF97483.1 - 0.025 14.0 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EGF97483.1 - 0.027 14.0 0.0 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Di19_C PF14571.1 EGF97484.1 - 4 7.8 10.2 0.17 12.2 1.3 2.6 2 1 1 3 3 3 0 Stress-induced protein Di19, C-terminal DUF1762 PF08574.5 EGF97485.1 - 0.029 14.7 1.1 0.064 13.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1762) DUF1770 PF08589.5 EGF97487.1 - 0.00044 20.8 0.1 0.0014 19.2 0.1 2.2 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Ribosomal_L27e PF01777.13 EGF97489.1 - 6.3e-38 128.7 0.7 8.3e-38 128.3 0.5 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EGF97489.1 - 0.00012 21.6 0.7 0.00034 20.2 0.5 1.8 1 0 0 1 1 1 1 KOW motif Phage_portal PF04860.7 EGF97489.1 - 0.058 12.0 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein Sigma70_r1_2 PF00140.15 EGF97490.1 - 1.2 8.8 5.5 1.9 8.2 3.8 1.3 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 DUF4145 PF13643.1 EGF97491.1 - 0.0048 16.7 0.0 0.036 13.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4145) PI-PLC-Y PF00387.14 EGF97491.1 - 0.1 12.5 1.8 0.15 12.0 1.3 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain Ebp2 PF05890.7 EGF97491.1 - 0.21 10.8 8.4 0.25 10.5 5.8 1.1 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 DUF4337 PF14235.1 EGF97491.1 - 5.7 6.7 6.0 7.6 6.3 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Late_protein_L1 PF00500.13 EGF97493.1 - 0.0012 17.4 0.0 0.0012 17.4 0.0 1.0 1 0 0 1 1 1 1 L1 (late) protein IpgD PF05925.7 EGF97494.1 - 0.015 13.5 0.4 0.022 13.0 0.3 1.2 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD Synaptonemal_3 PF15191.1 EGF97495.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 LBP_BPI_CETP PF01273.20 EGF97498.1 - 0.028 13.7 0.9 0.077 12.3 0.1 2.1 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain CCDC50_N PF15295.1 EGF97498.1 - 0.044 13.6 4.7 0.098 12.5 3.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus PRP1_N PF06424.7 EGF97498.1 - 0.068 13.4 2.2 0.14 12.4 1.5 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal FliE PF02049.13 EGF97498.1 - 0.48 10.4 6.0 1 9.4 2.2 2.6 2 1 0 2 2 2 0 Flagellar hook-basal body complex protein FliE AAA_11 PF13086.1 EGF97498.1 - 2.3 7.7 7.7 0.53 9.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain Allexi_40kDa PF05549.6 EGF97498.1 - 6.6 5.9 10.7 1.5 8.0 2.0 2.4 1 1 2 3 3 3 0 Allexivirus 40kDa protein DBD_Tnp_Mut PF03108.10 EGF97499.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 MuDR family transposase API5 PF05918.6 EGF97500.1 - 1.8 6.9 10.7 2.4 6.5 7.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RTC PF01137.16 EGF97501.1 - 6.1e-50 169.1 0.0 7.7e-50 168.8 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EGF97501.1 - 1.7e-28 98.6 0.0 2.7e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain LRR_8 PF13855.1 EGF97502.1 - 0.41 10.4 3.4 1.5 8.6 0.0 3.4 4 0 0 4 4 4 0 Leucine rich repeat AA_permease PF00324.16 EGF97503.1 - 3.8e-28 98.0 13.1 4.7e-28 97.7 9.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGF97503.1 - 1.5e-07 30.3 7.1 1.7e-07 30.1 4.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF485 PF04341.7 EGF97503.1 - 0.52 10.0 3.3 0.25 11.0 0.9 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DUF4494 PF14902.1 EGF97505.1 - 0.052 13.1 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4494) CobN-Mg_chel PF02514.11 EGF97506.1 - 0.046 11.1 0.1 0.073 10.4 0.1 1.2 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Baculo_PEP_C PF04513.7 EGF97506.1 - 0.082 12.7 2.7 0.14 11.9 1.0 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 EGF97506.1 - 0.086 11.7 15.9 0.068 12.0 5.7 2.7 3 1 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 PLA2_B PF01735.13 EGF97507.1 - 3.3e-87 292.7 0.0 2.8e-52 177.5 0.0 2.3 2 0 0 2 2 2 2 Lysophospholipase catalytic domain CHRD PF07452.7 EGF97511.1 - 0.049 14.2 0.1 0.38 11.3 0.0 2.1 2 0 0 2 2 2 0 CHRD domain Ribosomal_L34e PF01199.13 EGF97512.1 - 1.2 9.4 6.3 0.19 11.9 0.8 2.3 2 0 0 2 2 2 0 Ribosomal protein L34e FYVE PF01363.16 EGF97515.1 - 3.3 7.6 8.1 7.2 6.5 5.6 1.5 1 1 0 1 1 1 0 FYVE zinc finger Nucleo_P87 PF07267.6 EGF97516.1 - 0.36 9.4 3.2 0.59 8.7 2.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.1 EGF97516.1 - 1 9.7 8.3 3 8.2 5.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 EGF97518.1 - 1e-15 56.8 0.0 1e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Peptidase_M90 PF06167.7 EGF97521.1 - 0.0028 17.0 0.1 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Glucose-regulated metallo-peptidase M90 MAAL_C PF07476.6 EGF97521.1 - 0.12 11.3 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus UCR_TM PF02921.9 EGF97522.1 - 1.2e-19 70.3 2.0 1.8e-19 69.7 1.4 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EGF97522.1 - 9e-18 63.6 0.0 1.3e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Mito_fiss_reg PF05308.6 EGF97527.1 - 6 6.1 9.8 2.7 7.3 5.5 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator V-ATPase_G PF03179.10 EGF97530.1 - 0.26 11.6 6.8 0.26 11.6 0.6 2.7 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF2793 PF10983.3 EGF97533.1 - 0.052 13.3 0.6 0.11 12.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) UIM PF02809.15 EGF97533.1 - 0.38 10.4 0.0 0.38 10.4 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin interaction motif Peptidase_M24 PF00557.19 EGF97535.1 - 2.5e-45 154.6 0.0 3.3e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGF97535.1 - 5.8e-40 135.7 0.0 1.1e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain CBM_5_12_2 PF14600.1 EGF97536.1 - 0.081 12.5 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Cellulose-binding domain PRD_Mga PF08270.6 EGF97537.1 - 0.79 8.9 8.7 1.3 8.2 0.7 2.5 2 1 1 3 3 3 0 M protein trans-acting positive regulator (MGA) PRD domain Frataxin_Cyay PF01491.11 EGF97538.1 - 0.004 16.9 0.1 0.058 13.1 0.0 2.1 2 0 0 2 2 2 1 Frataxin-like domain TATR PF03430.8 EGF97540.1 - 5.4e-06 25.3 3.3 7.8e-06 24.8 2.3 1.3 1 0 0 1 1 1 1 Trans-activating transcriptional regulator RPA_interact_M PF14767.1 EGF97542.1 - 0.0082 16.8 0.0 0.018 15.7 0.0 1.5 1 0 0 1 1 1 1 Replication protein A interacting middle HMG_box PF00505.14 EGF97543.1 - 0.034 14.4 0.0 0.61 10.3 0.0 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box RE_EcoO109I PF14511.1 EGF97543.1 - 0.11 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I Helicase_C PF00271.26 EGF97545.1 - 4.7e-14 51.9 0.0 7.5e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UPF0506 PF11703.3 EGF97547.1 - 0.14 12.1 2.7 2.1 8.3 0.3 2.3 2 0 0 2 2 2 0 UPF0506 DUF566 PF04484.7 EGF97548.1 - 0.74 9.2 5.9 0.95 8.9 4.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) adh_short PF00106.20 EGF97549.1 - 0.018 14.9 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase DUF3382 PF11862.3 EGF97550.1 - 1.9 8.4 6.4 6.4 6.7 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) Aldedh PF00171.17 EGF97553.1 - 8.1e-111 370.6 0.0 9.3e-111 370.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGF97553.1 - 0.0017 17.1 0.0 0.0027 16.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Prothymosin PF03247.9 EGF97555.1 - 0.053 13.6 43.8 0.42 10.7 17.9 2.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family DDHD PF02862.12 EGF97555.1 - 6.3 6.5 11.1 7.4 6.3 0.4 2.4 2 0 0 2 2 2 0 DDHD domain Apolipoprotein PF01442.13 EGF97557.1 - 0.028 13.9 0.0 0.066 12.7 0.0 1.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.6 EGF97557.1 - 0.042 13.8 0.5 0.083 12.9 0.4 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) COG2 PF06148.6 EGF97557.1 - 0.044 13.6 0.9 0.099 12.5 0.5 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DDE_3 PF13358.1 EGF97559.1 - 1.2e-08 34.8 0.0 2.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_14 PF13173.1 EGF97559.1 - 0.04 13.8 0.2 0.56 10.1 0.1 2.1 1 1 1 2 2 2 0 AAA domain HTH_32 PF13565.1 EGF97559.1 - 0.082 13.7 0.0 0.29 11.9 0.0 2.0 2 1 0 2 2 2 0 Homeodomain-like domain Toxin_1 PF00087.16 EGF97561.1 - 0.026 14.8 1.1 0.047 14.0 0.8 1.4 1 0 0 1 1 1 0 Snake toxin Mucin PF01456.12 EGF97562.1 - 0.32 10.7 6.7 0.26 11.0 1.1 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Corona_5a PF06336.6 EGF97564.1 - 0.019 14.8 0.2 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Coronavirus 5a protein Rop PF01815.11 EGF97565.1 - 0.05 13.0 0.3 6.6 6.2 0.1 2.3 2 0 0 2 2 2 0 Rop protein DUF904 PF06005.7 EGF97566.1 - 0.00051 20.2 3.2 0.00084 19.5 2.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF904) HATPase_c_3 PF13589.1 EGF97568.1 - 9.1e-05 22.1 0.0 0.0001 21.9 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGF97568.1 - 0.0076 15.9 0.0 0.0086 15.7 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Parecho_VpG PF06344.6 EGF97569.1 - 0.81 9.6 5.1 2.4 8.1 3.6 1.8 1 0 0 1 1 1 0 Parechovirus Genome-linked protein Ycf1 PF05758.7 EGF97570.1 - 0.14 9.8 3.0 0.13 9.9 2.1 1.1 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 EGF97570.1 - 0.31 10.3 16.7 0.35 10.2 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 EGF97570.1 - 1.7 8.0 14.6 2.2 7.7 10.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO BUD22 PF09073.5 EGF97570.1 - 3.5 6.5 21.8 4.5 6.2 15.1 1.2 1 0 0 1 1 1 0 BUD22 Astro_capsid PF03115.9 EGF97570.1 - 6 4.9 7.4 6 4.9 5.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Pilt PF15453.1 EGF97570.1 - 6.3 6.3 8.9 7.5 6.1 6.2 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Nop14 PF04147.7 EGF97570.1 - 6.7 4.4 34.9 7.4 4.3 24.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4197 PF13852.1 EGF97571.1 - 0.033 13.7 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) API5 PF05918.6 EGF97572.1 - 0.18 10.2 9.3 0.22 10.0 6.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PAT1 PF09770.4 EGF97573.1 - 4.3 5.4 4.8 4.6 5.3 3.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SWIM PF04434.12 EGF97576.1 - 1.6e-05 24.2 8.5 0.00099 18.5 0.3 2.6 2 0 0 2 2 2 2 SWIM zinc finger DUF4191 PF13829.1 EGF97580.1 - 0.043 12.9 0.1 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF1177 PF06675.6 EGF97580.1 - 0.095 11.2 0.1 0.12 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) DnaJ PF00226.26 EGF97581.1 - 6.7e-05 22.5 0.2 0.00015 21.4 0.1 1.6 1 1 0 1 1 1 1 DnaJ domain HAD_2 PF13419.1 EGF97582.1 - 5.7e-11 42.9 0.1 2.5e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGF97582.1 - 0.0075 15.9 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EGF97582.1 - 0.099 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Xpo1 PF08389.7 EGF97584.1 - 0.044 13.6 1.0 4.6 7.1 0.2 2.2 2 0 0 2 2 2 0 Exportin 1-like protein HSP70 PF00012.15 EGF97586.1 - 0.025 12.4 0.7 0.029 12.2 0.5 1.1 1 0 0 1 1 1 0 Hsp70 protein Gln-synt_C PF00120.19 EGF97592.1 - 1.9e-48 164.8 0.0 2.9e-48 164.2 0.0 1.3 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EGF97592.1 - 2.8e-17 62.0 0.0 4.7e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF4226 PF10774.4 EGF97593.1 - 1.3 9.1 11.3 9.3 6.3 0.1 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4226) FYVE_2 PF02318.11 EGF97593.1 - 3.3 7.6 15.3 3.7 7.4 1.1 4.0 3 1 1 4 4 4 0 FYVE-type zinc finger RRM_1 PF00076.17 EGF97595.1 - 0.2 11.3 0.1 5.1 6.8 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ARPC4 PF05856.7 EGF97597.1 - 4.6e-69 231.1 0.5 5.1e-69 231.0 0.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Borrelia_P83 PF05262.6 EGF97598.1 - 0.00079 17.8 4.9 0.00088 17.6 3.4 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein DUF874 PF05917.6 EGF97598.1 - 0.078 11.8 5.3 0.11 11.3 3.7 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF3653 PF12375.3 EGF97598.1 - 0.97 9.6 6.1 0.48 10.6 1.7 2.3 2 0 0 2 2 2 0 Phage protein DUF3395 PF11875.3 EGF97598.1 - 1 8.9 6.3 1.6 8.3 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Ras PF00071.17 EGF97600.1 - 4.5e-34 117.1 0.0 5.5e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGF97600.1 - 2e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGF97600.1 - 0.0011 18.2 0.0 0.0015 17.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 EGF97600.1 - 0.052 13.0 0.0 0.075 12.5 0.0 1.3 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF3449 PF11931.3 EGF97601.1 - 0.043 13.3 0.1 0.043 13.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) PAS_4 PF08448.5 EGF97601.1 - 0.055 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 PAS fold IL11 PF07400.6 EGF97603.1 - 0.0057 16.2 0.2 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 Interleukin 11 Matrilin_ccoil PF10393.4 EGF97603.1 - 0.07 12.4 0.6 0.15 11.4 0.4 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin UBN2_2 PF14227.1 EGF97606.1 - 1.6e-08 34.1 0.0 3.5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGF97606.1 - 3.4e-08 33.3 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EGF97606.1 - 0.00034 20.1 0.5 0.00068 19.2 0.4 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.10 EGF97606.1 - 0.0087 15.8 0.0 0.05 13.4 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1759) Peptidase_M17_N PF02789.12 EGF97606.1 - 0.062 13.0 0.1 0.14 11.9 0.0 1.5 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain HMG_box_2 PF09011.5 EGF97608.1 - 0.0096 16.2 0.5 0.022 15.1 0.3 1.6 1 0 0 1 1 1 1 HMG-box domain SNF2_N PF00176.18 EGF97610.1 - 3.1e-44 150.9 1.0 3.4e-44 150.8 0.7 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGF97610.1 - 1.6e-07 30.9 0.0 2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGF97610.1 - 0.0065 16.3 0.0 0.011 15.5 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGF97611.1 - 1.7e-13 50.2 0.0 3.5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Monellin PF09200.5 EGF97612.1 - 0.048 13.3 0.3 0.15 11.7 0.2 1.9 1 1 0 1 1 1 0 Monellin Dot_icm_IcmQ PF09475.5 EGF97618.1 - 0.011 14.9 0.4 0.014 14.6 0.3 1.3 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Mito_carr PF00153.22 EGF97620.1 - 1.5e-08 34.2 0.0 1.6e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Herpes_env PF01673.13 EGF97622.1 - 8.7 4.7 12.2 2.9 6.3 6.6 1.4 1 1 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein WSK PF03832.8 EGF97623.1 - 0.081 12.2 0.6 0.081 12.2 0.4 2.3 2 1 0 2 2 2 0 WSK motif Hid1 PF12722.2 EGF97623.1 - 0.49 8.0 5.2 0.55 7.8 3.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Paf1 PF03985.8 EGF97623.1 - 4.7 5.8 8.2 6.5 5.3 5.7 1.1 1 0 0 1 1 1 0 Paf1 CD4-extracel PF09191.5 EGF97625.1 - 0.037 14.0 0.7 0.073 13.1 0.1 1.9 1 1 1 2 2 2 0 CD4, extracellular Sod_Cu PF00080.15 EGF97628.1 - 1.2e-09 38.5 0.4 3.6e-09 36.8 0.3 1.8 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Protoglobin PF11563.3 EGF97631.1 - 0.0069 16.0 0.0 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 Protoglobin Nuc_sug_transp PF04142.10 EGF97632.1 - 9.5e-36 123.1 2.0 1.1e-35 122.8 1.4 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EGF97632.1 - 1.5e-05 24.0 1.8 2.1e-05 23.6 1.2 1.3 1 1 0 1 1 1 1 UAA transporter family Srg PF02118.16 EGF97632.1 - 0.015 14.7 2.8 0.022 14.2 1.9 1.2 1 0 0 1 1 1 0 Srg family chemoreceptor GWT1 PF06423.7 EGF97632.1 - 0.027 14.5 1.3 0.038 14.0 0.9 1.2 1 0 0 1 1 1 0 GWT1 Lsm_interact PF05391.6 EGF97632.1 - 0.12 11.8 0.5 0.22 11.0 0.4 1.4 1 0 0 1 1 1 0 Lsm interaction motif GAF PF01590.21 EGF97635.1 - 0.058 13.5 0.0 0.76 9.8 0.0 2.4 3 0 0 3 3 3 0 GAF domain DUF1764 PF08576.5 EGF97637.1 - 0.053 14.2 0.1 0.058 14.1 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Toxin_38 PF14866.1 EGF97639.1 - 0.082 13.0 4.2 0.15 12.1 2.9 1.6 1 1 0 1 1 1 0 Potassium channel toxin DUF1962 PF09227.5 EGF97639.1 - 1.1 9.4 6.3 2.3 8.3 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) Glyco_transf_28 PF03033.15 EGF97640.1 - 2e-26 92.3 0.0 4.2e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EGF97640.1 - 2e-07 29.9 0.0 7.5e-07 28.0 0.0 1.8 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EGF97640.1 - 0.059 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Atrophin-1 PF03154.10 EGF97640.1 - 1.5 6.8 7.8 2.7 6.0 5.4 1.3 1 0 0 1 1 1 0 Atrophin-1 family DUF2201_N PF13203.1 EGF97640.1 - 2 7.5 9.3 4 6.5 6.4 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain OAF PF14941.1 EGF97642.1 - 0.14 11.3 5.5 0.15 11.1 3.8 1.2 1 0 0 1 1 1 0 Transcriptional regulator, Out at first Prenylcys_lyase PF07156.9 EGF97645.1 - 1.1e-41 142.9 0.0 1.5e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EGF97645.1 - 7.9e-06 25.8 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGF97645.1 - 0.009 15.1 0.0 0.16 11.0 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EGF97645.1 - 0.0092 15.7 0.0 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding F_actin_cap_B PF01115.12 EGF97647.1 - 2.7e-100 334.5 0.3 3.2e-100 334.3 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.12 EGF97647.1 - 0.0011 18.0 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Acyl-CoA_dh_1 PF00441.19 EGF97649.1 - 5e-07 29.9 0.0 6.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EGF97649.1 - 0.0076 16.5 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SnoaL_2 PF12680.2 EGF97651.1 - 4.6e-06 26.9 0.1 6.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EGF97651.1 - 0.016 15.4 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 EGF97651.1 - 0.087 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain LRR_8 PF13855.1 EGF97653.1 - 0.00046 19.8 13.4 1.3 8.8 1.3 6.1 4 2 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 EGF97653.1 - 0.11 12.1 12.6 19 5.0 0.6 5.7 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGF97653.1 - 0.95 9.7 6.1 85 3.8 0.0 5.0 3 1 1 4 4 4 0 Leucine Rich Repeat Proteasome PF00227.21 EGF97654.1 - 5.2e-52 175.9 0.0 6.7e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGF97654.1 - 2.9e-13 48.8 0.1 5e-13 48.1 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature VQ PF05678.9 EGF97656.1 - 0.075 12.0 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 VQ motif Aldo_ket_red PF00248.16 EGF97658.1 - 3.5e-53 180.2 0.0 4e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Myb_DNA-bind_3 PF12776.2 EGF97659.1 - 8.6e-11 42.3 0.4 1.5e-10 41.5 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF1284 PF06935.6 EGF97661.1 - 0.046 13.9 1.0 0.15 12.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) Mitofilin PF09731.4 EGF97661.1 - 0.064 11.8 1.2 0.09 11.4 0.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PAS PF00989.19 EGF97662.1 - 0.00061 19.5 0.0 0.0034 17.1 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 EGF97662.1 - 0.0054 16.5 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 PAS domain FAM104 PF15434.1 EGF97665.1 - 0.00054 20.1 1.4 0.00054 20.1 1.0 1.7 1 1 1 2 2 2 1 Family 104 PIH1 PF08190.7 EGF97665.1 - 0.016 14.7 2.8 0.019 14.4 1.9 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Utp11 PF03998.8 EGF97666.1 - 3.8e-61 207.0 30.0 6e-61 206.3 20.8 1.3 1 1 0 1 1 1 1 Utp11 protein Flu_NS2 PF00601.14 EGF97666.1 - 0.0027 17.8 1.4 0.0087 16.2 0.1 2.6 3 0 0 3 3 3 1 Influenza non-structural protein (NS2) Rota_NS53 PF00981.12 EGF97666.1 - 0.0034 16.0 0.2 0.0057 15.3 0.1 1.4 1 0 0 1 1 1 1 Rotavirus RNA-binding Protein 53 (NS53) DUF357 PF04010.8 EGF97666.1 - 0.088 12.5 0.2 1.6 8.5 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF357) Transformer PF06495.6 EGF97666.1 - 7.1 6.4 15.6 5.1 6.9 5.3 2.5 2 0 0 2 2 2 0 Fruit fly transformer protein bZIP_1 PF00170.16 EGF97669.1 - 0.00019 21.2 16.9 0.019 14.9 1.1 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.12 EGF97669.1 - 0.0047 17.1 15.1 0.0088 16.3 10.5 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor FlgN PF05130.7 EGF97669.1 - 0.0093 16.2 4.5 0.013 15.7 3.2 1.2 1 0 0 1 1 1 1 FlgN protein bZIP_2 PF07716.10 EGF97669.1 - 0.89 9.4 21.4 1.9 8.3 14.8 1.6 1 0 0 1 1 1 0 Basic region leucine zipper TACC PF05010.9 EGF97669.1 - 1.9 8.2 7.9 3 7.5 5.5 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF3321 PF11968.3 EGF97670.1 - 4.2e-62 209.6 0.0 4.8e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EGF97670.1 - 1.9e-09 37.4 0.0 2.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGF97670.1 - 1.9e-07 31.4 0.0 3.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGF97670.1 - 0.0012 18.4 0.0 0.0056 16.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGF97670.1 - 0.005 17.2 0.0 0.0093 16.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PTS_EIIB PF00367.15 EGF97670.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 phosphotransferase system, EIIB Glyco_trans_1_2 PF13524.1 EGF97672.1 - 0.017 15.4 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Fibrillarin PF01269.12 EGF97674.1 - 2.4e-36 124.8 0.1 3.9e-20 71.7 0.0 2.0 1 1 1 2 2 2 2 Fibrillarin PhoD PF09423.5 EGF97678.1 - 3.5e-07 29.1 0.0 0.00036 19.2 0.0 2.0 1 1 1 2 2 2 2 PhoD-like phosphatase Metallophos PF00149.23 EGF97678.1 - 0.065 12.6 0.3 0.13 11.5 0.1 1.8 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase Memo PF01875.12 EGF97679.1 - 8.3e-23 80.6 0.0 9.5e-23 80.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein DUF816 PF05674.7 EGF97680.1 - 0.0019 17.9 3.9 0.62 9.7 0.9 2.1 1 1 1 2 2 2 2 Baculovirus protein of unknown function (DUF816) LdpA_C PF12617.3 EGF97680.1 - 0.019 14.2 2.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal HeLo PF14479.1 EGF97680.1 - 0.023 14.4 1.1 0.023 14.4 0.8 1.8 1 1 1 2 2 2 0 Prion-inhibition and propagation PilJ PF13675.1 EGF97680.1 - 0.027 14.7 0.7 0.43 10.8 0.1 2.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term NPV_P10 PF05531.7 EGF97680.1 - 0.056 13.6 2.3 0.49 10.6 0.4 2.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2564 PF10819.3 EGF97680.1 - 0.063 13.4 0.5 0.16 12.0 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2564) DUF3829 PF12889.2 EGF97680.1 - 0.074 12.2 8.7 0.11 11.6 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) WXG100 PF06013.7 EGF97680.1 - 0.089 12.8 1.8 3.6 7.6 0.2 3.1 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF1664 PF07889.7 EGF97680.1 - 0.26 11.0 9.4 1.2 8.9 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Dabb PF07876.7 EGF97680.1 - 0.27 11.7 1.6 1.6 9.2 0.1 2.5 1 1 1 2 2 2 0 Stress responsive A/B Barrel Domain DNA_repr_REX1B PF14966.1 EGF97680.1 - 0.94 9.8 8.4 0.85 10.0 2.7 2.1 1 1 1 2 2 2 0 DNA repair REX1-B Phage_GPO PF05929.6 EGF97680.1 - 1.8 7.7 7.4 2.4 7.3 5.1 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TPR_MLP1_2 PF07926.7 EGF97680.1 - 2 8.1 16.8 3.4 7.4 11.6 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 EGF97680.1 - 2.7 5.7 11.0 3.4 5.4 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.10 EGF97680.1 - 4 6.5 10.2 5.2 6.1 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3552 PF12072.3 EGF97680.1 - 7.2 5.7 20.6 0.2 10.8 7.8 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3552) Adeno_PIX PF03955.9 EGF97680.1 - 8.3 6.9 7.3 19 5.7 1.8 2.5 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF2203 PF09969.4 EGF97680.1 - 8.7 6.5 10.3 3.3 7.9 1.9 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Pkinase PF00069.20 EGF97681.1 - 5.1e-16 58.5 0.1 5.8e-16 58.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF97681.1 - 0.0059 15.7 0.0 0.0066 15.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase MIP-T3 PF10243.4 EGF97683.1 - 1.6 7.1 25.7 1.7 7.0 17.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 EGF97683.1 - 2.4 7.4 22.2 2.7 7.3 15.4 1.0 1 0 0 1 1 1 0 Vta1 like Spore_coat_CotO PF14153.1 EGF97683.1 - 3.9 6.8 11.6 4.9 6.5 8.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SLD3 PF08639.5 EGF97683.1 - 6 5.3 26.4 7.9 4.9 18.3 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 TFIIF_alpha PF05793.7 EGF97683.1 - 10 4.3 32.3 13 3.9 22.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NOA36 PF06524.7 EGF97688.1 - 3.8 6.6 10.3 4.9 6.3 7.1 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3727 PF12527.3 EGF97688.1 - 5.4 7.1 9.8 10 6.2 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) SDA1 PF05285.7 EGF97688.1 - 5.9 6.0 10.2 7.1 5.8 7.1 1.1 1 0 0 1 1 1 0 SDA1 zf-RING_2 PF13639.1 EGF97690.1 - 5.2e-10 38.9 0.7 8.6e-10 38.3 0.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGF97690.1 - 0.0038 17.3 1.4 0.0082 16.2 0.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGF97690.1 - 0.02 14.9 0.8 0.035 14.1 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGF97690.1 - 0.066 12.9 1.5 0.16 11.6 1.1 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Med7 PF05983.6 EGF97691.1 - 3.9e-08 33.2 0.9 2.1e-06 27.6 0.6 2.2 1 1 0 1 1 1 1 MED7 protein Sigma70_ner PF04546.8 EGF97691.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1116 PF06545.6 EGF97691.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) Baculo_PEP_C PF04513.7 EGF97692.1 - 0.0036 17.1 0.3 0.006 16.4 0.2 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Rootletin PF15035.1 EGF97692.1 - 0.0044 17.0 0.7 0.0068 16.4 0.5 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Reo_sigmaC PF04582.7 EGF97692.1 - 0.011 14.9 1.0 0.014 14.5 0.7 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF948 PF06103.6 EGF97692.1 - 0.031 14.1 2.0 0.048 13.5 1.1 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) COG5 PF10392.4 EGF97692.1 - 0.048 13.6 1.3 0.072 13.0 0.9 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 FlaC_arch PF05377.6 EGF97692.1 - 0.063 13.1 6.9 0.21 11.5 1.3 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) MbeD_MobD PF04899.7 EGF97692.1 - 0.067 13.1 0.7 0.21 11.4 0.5 1.9 1 1 0 1 1 1 0 MbeD/MobD like Phage_GP20 PF06810.6 EGF97692.1 - 0.1 12.0 3.2 0.17 11.3 2.2 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Spc7 PF08317.6 EGF97692.1 - 0.13 10.9 4.0 0.17 10.4 2.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EGF97692.1 - 0.16 11.8 5.4 0.29 10.9 2.5 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Rop-like PF05082.8 EGF97692.1 - 0.2 11.1 3.2 3.2 7.2 0.1 2.2 2 0 0 2 2 2 0 Rop-like XkdW PF09636.5 EGF97692.1 - 0.28 11.0 1.7 0.47 10.3 0.9 1.5 1 1 0 1 1 1 0 XkdW protein NPV_P10 PF05531.7 EGF97692.1 - 0.31 11.3 2.7 0.57 10.4 0.8 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EGF97692.1 - 0.33 10.7 4.3 0.51 10.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Integrase_DNA PF02920.10 EGF97694.1 - 0.055 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase Syntaxin-6_N PF09177.6 EGF97694.1 - 5.7 7.4 7.3 3.3 8.1 1.6 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal FYVE_2 PF02318.11 EGF97704.1 - 0.35 10.7 2.8 0.46 10.4 1.9 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger Med13_C PF06333.7 EGF97709.1 - 3.6 6.0 6.7 4.8 5.6 4.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal ABC2_membrane PF01061.19 EGF97712.1 - 3.2e-23 82.0 12.0 4.9e-23 81.4 8.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter SNF2_N PF00176.18 EGF97713.1 - 1.2e-54 185.1 1.1 1.8e-31 109.0 0.1 2.1 1 1 1 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.10 EGF97713.1 - 0.006 16.4 2.2 0.025 14.4 0.0 2.5 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGF97713.1 - 0.011 15.2 0.1 1.6 8.2 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase UPF0154 PF03672.8 EGF97713.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Zot PF05707.7 EGF97713.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Rrn6 PF10214.4 EGF97715.1 - 8.9 4.2 20.6 12 3.8 14.3 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MRP-S26 PF14943.1 EGF97717.1 - 0.0085 15.6 0.6 0.016 14.7 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 Pkinase PF00069.20 EGF97718.1 - 4e-61 206.4 0.0 4.9e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF97718.1 - 8.6e-44 149.5 0.0 1.1e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGF97718.1 - 3e-05 23.1 0.0 4.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EGF97718.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EGF97718.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGF97718.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EGF97718.1 - 0.068 12.8 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATG2_CAD PF13329.1 EGF97720.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif Nop14 PF04147.7 EGF97721.1 - 0.37 8.6 26.0 0.4 8.5 18.0 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EGF97721.1 - 0.96 8.4 37.2 1.2 8.1 25.8 1.2 1 0 0 1 1 1 0 BUD22 DUF572 PF04502.8 EGF97721.1 - 6.5 5.8 20.7 10 5.2 14.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) TATR PF03430.8 EGF97721.1 - 7.1 5.1 15.8 9 4.8 11.0 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Macoilin PF09726.4 EGF97721.1 - 8.6 4.5 31.7 9.4 4.3 22.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3129 PF11327.3 EGF97723.1 - 7.2e-17 61.7 2.7 7.2e-17 61.7 1.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3129) Mating_C PF12737.2 EGF97724.1 - 0.037 12.9 4.6 0.46 9.3 1.3 2.1 2 0 0 2 2 2 0 C-terminal domain of homeodomain 1 zf-CCHC PF00098.18 EGF97728.1 - 2.9e-07 30.1 10.0 3.2e-05 23.6 1.2 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EGF97728.1 - 0.1 12.2 3.8 0.75 9.5 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 EGF97728.1 - 0.41 10.1 9.5 1.3 8.6 1.3 2.6 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 EGF97728.1 - 0.83 9.4 3.3 18 5.1 0.3 2.5 1 1 1 2 2 2 0 Zinc knuckle APS_kinase PF01583.15 EGF97729.1 - 5.6e-66 221.0 0.0 6.7e-66 220.7 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EGF97729.1 - 1.8e-07 31.1 0.0 2.4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGF97729.1 - 1.9e-07 31.4 0.2 3.5e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGF97729.1 - 6.4e-07 30.2 0.0 1e-06 29.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGF97729.1 - 5.6e-05 22.4 0.0 7.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 SRP54 PF00448.17 EGF97729.1 - 0.0005 19.5 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 EGF97729.1 - 0.0018 17.6 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EGF97729.1 - 0.0022 17.7 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGF97729.1 - 0.0024 17.8 0.1 0.0043 17.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain PRK PF00485.13 EGF97729.1 - 0.0028 17.2 0.0 0.0057 16.2 0.0 1.5 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 EGF97729.1 - 0.0034 16.8 0.0 0.0055 16.1 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 EGF97729.1 - 0.0036 16.8 0.1 0.006 16.0 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EGF97729.1 - 0.0095 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin PEPCK_ATP PF01293.15 EGF97729.1 - 0.013 14.0 0.1 0.016 13.7 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase RNA_helicase PF00910.17 EGF97729.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EGF97729.1 - 0.025 14.8 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.12 EGF97729.1 - 0.056 13.2 0.9 2.9 7.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 ArgK PF03308.11 EGF97729.1 - 0.062 12.0 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Clusterin PF01093.12 EGF97729.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Clusterin DUF258 PF03193.11 EGF97729.1 - 0.15 11.1 0.1 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TEX33 PF15400.1 EGF97730.1 - 0.16 12.4 0.3 0.3 11.4 0.2 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 33 protein family DUF702 PF05142.7 EGF97731.1 - 0.0068 16.5 8.4 0.011 15.9 4.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF702) His_Phos_1 PF00300.17 EGF97732.1 - 1.2e-14 54.6 0.0 1.7e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) STE3 PF02076.10 EGF97739.1 - 3.8e-57 193.5 12.5 4.5e-57 193.3 8.7 1.0 1 0 0 1 1 1 1 Pheromone A receptor zf-TRM13_CCCH PF11722.3 EGF97740.1 - 0.0051 16.1 0.6 20 4.6 0.0 3.1 3 0 0 3 3 3 3 CCCH zinc finger in TRM13 protein Pax7 PF12360.3 EGF97740.1 - 0.042 14.1 1.0 14 6.0 0.0 3.1 1 1 2 3 3 3 0 Paired box protein 7 YpM PF09144.5 EGF97740.1 - 0.22 11.5 3.1 0.62 10.0 0.7 1.9 1 1 2 3 3 3 0 Yersinia pseudotuberculosis mitogen Phage_GP20 PF06810.6 EGF97741.1 - 0.11 11.9 6.3 0.19 11.1 4.4 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 IncA PF04156.9 EGF97741.1 - 1.3 8.6 3.6 2.4 7.7 2.5 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EGF97741.1 - 1.5 6.5 5.7 2.3 5.9 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EGF97741.1 - 3.2 6.7 6.7 5.4 5.9 4.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Cys_rich_FGFR PF00839.12 EGF97743.1 - 0.31 10.9 2.8 11 6.0 0.2 2.4 1 1 1 2 2 2 0 Cysteine rich repeat FAR1 PF03101.10 EGF97745.1 - 0.00052 20.4 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EGF97746.1 - 0.00037 20.6 0.3 0.00037 20.6 0.2 2.6 3 1 0 3 3 3 1 Transcription factor AFT IncA PF04156.9 EGF97747.1 - 4.6 6.7 6.4 7.1 6.1 1.0 2.4 2 0 0 2 2 2 0 IncA protein HTH_28 PF13518.1 EGF97748.1 - 9.9e-05 22.2 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EGF97748.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EGF97748.1 - 0.011 15.3 0.1 0.034 13.7 0.1 1.9 1 1 0 1 1 1 0 Homeodomain-like domain HTH_33 PF13592.1 EGF97748.1 - 0.015 14.8 0.0 0.089 12.3 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix SelB-wing_3 PF09107.6 EGF97748.1 - 0.017 14.4 0.0 0.8 9.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor SelB, winged helix HTH_32 PF13565.1 EGF97748.1 - 0.03 15.1 0.1 0.99 10.2 0.0 2.2 1 1 1 2 2 2 0 Homeodomain-like domain SNN_linker PF09050.5 EGF97749.1 - 0.042 13.3 0.2 0.092 12.3 0.1 1.5 1 0 0 1 1 1 0 Stannin unstructured linker Ogr_Delta PF04606.7 EGF97752.1 - 0.29 10.8 7.1 0.53 9.9 1.0 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger NPV_P10 PF05531.7 EGF97753.1 - 0.037 14.2 1.2 0.12 12.6 0.8 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Fzo_mitofusin PF04799.8 EGF97753.1 - 0.086 12.2 3.4 0.73 9.1 0.3 2.5 2 0 0 2 2 2 0 fzo-like conserved region DUF3573 PF12097.3 EGF97753.1 - 0.63 8.6 3.8 1.5 7.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Tropomyosin_1 PF12718.2 EGF97754.1 - 0.00084 19.2 0.2 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 Tropomyosin like PBP1_TM PF14812.1 EGF97755.1 - 1.1 9.6 14.0 1.4 9.3 1.4 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WWbp PF10349.4 EGF97755.1 - 6.9 7.5 13.3 33 5.3 4.8 2.4 1 1 1 2 2 2 0 WW-domain ligand protein Mtc PF03820.12 EGF97756.1 - 3.5e-95 318.2 0.0 3.9e-95 318.0 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier NAM-associated PF14303.1 EGF97757.1 - 4e-09 36.9 0.3 6e-09 36.3 0.2 1.3 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Spo12 PF05032.7 EGF97757.1 - 0.065 12.8 0.2 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Spo12 family CtaG_Cox11 PF04442.9 EGF97758.1 - 1.2e-56 190.7 0.0 1.7e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 NUDIX PF00293.23 EGF97759.1 - 2.8e-08 33.4 0.0 3.7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SMC_N PF02463.14 EGF97764.1 - 2.5e-61 206.7 0.0 4.1e-61 206.0 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGF97764.1 - 9.7e-30 103.0 0.4 3.3e-29 101.3 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGF97764.1 - 1.1e-10 41.9 4.4 0.00023 21.2 0.0 3.2 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EGF97764.1 - 1.5e-10 41.7 8.3 1.5e-10 41.7 5.7 6.2 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 EGF97764.1 - 4.3e-09 35.7 0.0 1.3e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EGF97764.1 - 0.00084 19.2 0.1 0.0056 16.5 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EGF97764.1 - 0.0013 17.8 0.0 0.0013 17.8 0.0 4.5 4 1 0 4 4 4 1 AAA ATPase domain Seryl_tRNA_N PF02403.17 EGF97764.1 - 0.0015 18.5 1.7 0.0015 18.5 1.2 9.7 6 4 4 10 10 10 2 Seryl-tRNA synthetase N-terminal domain ABC_tran PF00005.22 EGF97764.1 - 0.22 11.8 0.0 0.22 11.8 0.0 6.5 4 3 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 EGF97764.1 - 5.5 6.0 23.1 0.027 13.6 2.2 4.5 4 1 0 5 5 5 0 Reovirus sigma C capsid protein PolC_DP2 PF03833.8 EGF97765.1 - 0.18 9.4 8.4 0.19 9.3 5.8 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Ribosomal_S27e PF01667.12 EGF97765.1 - 0.25 10.8 7.3 1.1 8.8 1.4 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 EGF97765.1 - 1.1 8.6 8.7 0.2 10.9 0.5 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Opy2 PF09463.5 EGF97765.1 - 1.1 9.4 9.9 0.27 11.3 3.5 2.3 2 0 0 2 2 2 0 Opy2 protein Zn_Tnp_IS1595 PF12760.2 EGF97765.1 - 1.1 9.0 14.0 2.1 8.1 7.7 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain B-block_TFIIIC PF04182.7 EGF97766.1 - 0.0052 16.6 0.0 6.9 6.5 0.0 3.4 4 0 0 4 4 4 2 B-block binding subunit of TFIIIC His_Phos_2 PF00328.17 EGF97768.1 - 6.2e-42 144.1 0.0 7.8e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) BLOC1_2 PF10046.4 EGF97770.1 - 0.0044 17.1 1.1 0.0089 16.1 0.5 1.6 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.7 EGF97770.1 - 0.027 12.6 0.4 0.038 12.1 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Allexi_40kDa PF05549.6 EGF97770.1 - 0.028 13.7 1.1 0.045 13.0 0.8 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein NPV_P10 PF05531.7 EGF97770.1 - 0.033 14.4 2.8 0.22 11.8 1.1 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein LPP PF04728.8 EGF97770.1 - 0.034 13.9 2.4 2.5 7.9 0.2 2.4 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 EGF97770.1 - 0.052 12.7 1.7 0.097 11.8 1.2 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Vps5 PF09325.5 EGF97770.1 - 0.056 12.6 2.1 0.079 12.2 1.5 1.1 1 0 0 1 1 1 0 Vps5 C terminal like Sec5 PF15469.1 EGF97770.1 - 0.09 12.4 0.5 0.14 11.9 0.4 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 Phasin PF05597.6 EGF97770.1 - 0.15 11.8 0.9 0.3 10.8 0.6 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.7 EGF97770.1 - 0.17 11.7 0.7 0.29 10.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MbeD_MobD PF04899.7 EGF97770.1 - 0.21 11.5 1.8 19 5.2 0.1 2.9 2 1 1 3 3 3 0 MbeD/MobD like SelP_N PF04592.9 EGF97772.1 - 0.11 11.8 15.8 0.12 11.7 11.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pkinase PF00069.20 EGF97775.1 - 2.3e-62 210.5 0.0 3.4e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF97775.1 - 2.8e-37 128.2 0.0 9.4e-37 126.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGF97775.1 - 6.7e-06 25.2 0.0 1.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGF97775.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EGF97775.1 - 0.029 14.1 0.0 0.099 12.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2217 PF10265.4 EGF97775.1 - 0.78 8.4 2.9 1.1 7.9 2.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) NST1 PF13945.1 EGF97775.1 - 4.6 7.2 9.8 2 8.4 0.1 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator Ufd2P_core PF10408.4 EGF97776.1 - 1.5e-168 561.9 6.8 1.5e-168 561.9 4.7 1.4 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.10 EGF97776.1 - 6.4e-29 99.7 3.5 6.6e-29 99.6 0.9 2.3 2 0 0 2 2 2 1 U-box domain PPI_Ypi1 PF07491.6 EGF97777.1 - 1.2e-23 82.4 0.4 2.9e-23 81.2 0.3 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor FLYWCH_N PF15423.1 EGF97782.1 - 0.044 13.9 1.6 0.13 12.4 1.1 1.8 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein Sec2p PF06428.6 EGF97783.1 - 0.025 14.4 0.5 0.048 13.5 0.4 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p zf-ZPR1 PF03367.8 EGF97785.1 - 3.7 6.6 10.9 0.42 9.7 3.3 2.6 2 1 1 3 3 3 0 ZPR1 zinc-finger domain GAS PF13851.1 EGF97785.1 - 3.8 6.6 61.2 0.085 12.0 13.3 4.8 3 2 2 5 5 5 0 Growth-arrest specific micro-tubule binding Melibiase PF02065.13 EGF97786.1 - 3.8e-06 25.8 0.0 1.8e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Melibiase CorA PF01544.13 EGF97787.1 - 2e-42 145.2 0.1 2.5e-42 144.9 0.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 EGF97787.1 - 0.0051 16.6 1.0 0.0099 15.7 0.2 1.8 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3826 PF12875.2 EGF97787.1 - 0.05 13.3 0.2 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) ACT_4 PF13291.1 EGF97787.1 - 0.056 13.7 0.0 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 ACT domain RasGAP PF00616.14 EGF97788.1 - 0.017 14.7 2.3 0.43 10.2 0.2 2.8 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Aminotran_4 PF01063.14 EGF97789.1 - 7.9e-23 81.1 0.0 1.2e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Tom22 PF04281.8 EGF97791.1 - 0.021 14.3 0.1 0.032 13.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 CCD PF07860.6 EGF97795.1 - 2 7.8 6.1 0.82 9.1 1.5 2.2 2 1 1 3 3 3 0 WisP family C-Terminal Region DnaJ PF00226.26 EGF97798.1 - 6.6e-05 22.5 0.2 0.00015 21.4 0.1 1.6 1 1 0 1 1 1 1 DnaJ domain HAD_2 PF13419.1 EGF97799.1 - 6.4e-12 46.0 0.0 1.7e-09 38.1 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGF97799.1 - 0.0039 16.8 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EGF97799.1 - 0.08 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FAD_binding_4 PF01565.18 EGF97800.1 - 3.3e-22 78.4 0.9 5.7e-22 77.6 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGF97800.1 - 1.3e-08 34.6 0.1 2.7e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like 3Beta_HSD PF01073.14 EGF97801.1 - 4.9e-13 48.4 0.0 1e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGF97801.1 - 9.8e-09 34.9 0.1 4.4e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGF97801.1 - 2e-08 33.4 0.1 7.9e-08 31.5 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGF97801.1 - 1e-06 28.8 0.4 8.7e-06 25.8 0.3 2.4 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EGF97801.1 - 0.13 12.1 0.5 0.47 10.3 0.3 1.9 1 1 0 1 1 1 0 short chain dehydrogenase Ribonucleas_3_3 PF14622.1 EGF97802.1 - 0.0068 16.3 0.0 0.024 14.6 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EGF97802.1 - 0.023 15.2 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EGF97802.1 - 0.026 14.9 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease III domain Ribosomal_S5 PF00333.15 EGF97802.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain GPI-anchored PF10342.4 EGF97804.1 - 0.00036 20.9 0.0 0.0014 19.0 0.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ADH_N PF08240.7 EGF97805.1 - 5.2e-25 87.3 2.2 1.5e-24 85.8 0.2 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGF97805.1 - 5.1e-22 77.8 0.1 9.2e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EGF97805.1 - 0.025 14.1 0.3 0.07 12.6 0.1 1.8 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain P2X_receptor PF00864.14 EGF97805.1 - 0.074 11.7 0.7 0.12 11.1 0.5 1.2 1 0 0 1 1 1 0 ATP P2X receptor TrkA_N PF02254.13 EGF97805.1 - 0.15 12.0 0.1 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain ADH_N PF08240.7 EGF97809.1 - 1.7e-24 85.6 1.5 2.3e-24 85.2 0.2 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGF97809.1 - 1.1e-19 70.2 0.0 2.3e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGF97809.1 - 0.004 18.0 0.0 0.0068 17.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EGF97809.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 EGF97809.1 - 0.053 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 EGF97809.1 - 0.06 13.3 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain P2X_receptor PF00864.14 EGF97809.1 - 0.093 11.4 0.2 0.15 10.7 0.2 1.2 1 0 0 1 1 1 0 ATP P2X receptor DDE_3 PF13358.1 EGF97810.1 - 2.9e-14 53.0 0.0 3.2e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EGF97811.1 - 0.034 14.0 1.1 0.049 13.5 0.1 1.8 2 0 0 2 2 2 0 Zinc knuckle DUF4219 PF13961.1 EGF97811.1 - 0.16 11.4 0.2 0.32 10.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-CCHC_2 PF13696.1 EGF97811.1 - 0.19 11.2 4.0 0.47 9.9 2.8 1.7 1 0 0 1 1 1 0 Zinc knuckle Glycos_transf_2 PF00535.21 EGF97812.1 - 0.00072 19.2 4.0 0.065 12.9 0.4 2.5 1 1 1 2 2 2 2 Glycosyl transferase family 2 MIP PF00230.15 EGF97813.1 - 2.1e-13 50.2 5.5 2.6e-13 49.9 3.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF4516 PF14990.1 EGF97813.1 - 0.43 10.1 2.7 15 5.2 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) FeoB_C PF07664.7 EGF97813.1 - 7.5 6.0 11.5 2 7.8 1.3 3.3 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus 3Beta_HSD PF01073.14 EGF97814.1 - 1.2e-14 53.6 0.0 2.3e-14 52.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGF97814.1 - 2.8e-13 49.8 0.0 8.1e-13 48.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGF97814.1 - 5.2e-12 45.2 0.0 1.5e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGF97814.1 - 1.3e-08 35.0 0.8 4.4e-08 33.3 0.5 2.1 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGF97814.1 - 4.1e-05 23.5 0.5 0.00044 20.2 0.4 2.3 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGF97814.1 - 0.0017 17.2 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MTBP_N PF14918.1 EGF97814.1 - 0.055 12.8 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 MDM2-binding RmlD_sub_bind PF04321.12 EGF97814.1 - 0.09 11.6 0.0 0.3 9.9 0.0 1.9 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 EGF97814.1 - 0.16 11.1 0.8 0.31 10.2 0.3 1.8 2 1 0 2 2 2 0 NmrA-like family DUF3639 PF12341.3 EGF97814.1 - 1.6 8.8 4.1 2.5 8.1 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) Neisseria_TspB PF05616.8 EGF97815.1 - 0.079 11.3 0.1 0.09 11.1 0.1 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein AAA_10 PF12846.2 EGF97816.1 - 4.3e-08 32.9 0.1 5.6e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 AAA-like domain Zot PF05707.7 EGF97816.1 - 2e-06 27.3 0.0 3.3e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) DUF853 PF05872.7 EGF97816.1 - 0.0022 16.4 0.0 0.003 15.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) CPT PF07931.7 EGF97816.1 - 0.0088 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein DnaJ PF00226.26 EGF97817.1 - 3.3e-21 74.7 1.9 1.1e-20 73.1 1.3 2.0 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_2 PF02230.11 EGF97818.1 - 2.1e-18 66.5 0.1 1.3e-17 63.9 0.1 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGF97818.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.8 EGF97818.1 - 0.029 13.7 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DEAD PF00270.24 EGF97819.1 - 1.2e-43 148.5 0.0 8.1e-43 145.8 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGF97819.1 - 1.7e-22 79.0 0.0 1.7e-22 79.0 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGF97819.1 - 0.00022 21.1 0.0 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2608 PF11019.3 EGF97819.1 - 0.0035 16.3 0.3 0.0081 15.1 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2608) Helicase_C_2 PF13307.1 EGF97819.1 - 0.0037 17.2 0.2 0.044 13.7 0.0 2.4 2 0 0 2 2 2 1 Helicase C-terminal domain zf-CCHC_4 PF14392.1 EGF97819.1 - 0.046 13.3 1.2 0.11 12.1 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle SecA_DEAD PF07517.9 EGF97819.1 - 0.055 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain PBP_sp32 PF07222.7 EGF97819.1 - 0.27 10.3 3.4 0.46 9.6 2.4 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 zf-CCHC PF00098.18 EGF97819.1 - 0.27 11.2 2.4 0.66 10.0 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle UQ_con PF00179.21 EGF97820.1 - 8.7e-48 161.3 0.4 9.8e-48 161.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGF97820.1 - 0.0012 18.5 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGF97820.1 - 0.0044 16.9 0.5 0.011 15.5 0.3 1.7 1 1 1 2 2 2 1 RWD domain TPR_2 PF07719.12 EGF97822.1 - 2e-25 86.5 13.4 0.0018 18.0 0.4 9.4 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 EGF97822.1 - 4.5e-25 87.0 7.5 3.2e-08 33.0 0.1 6.9 6 1 1 7 7 7 5 TPR repeat Apc3 PF12895.2 EGF97822.1 - 6.5e-23 80.6 8.9 1.2e-08 34.9 0.0 6.8 6 1 1 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGF97822.1 - 2.4e-18 65.8 11.5 1.2e-07 31.5 0.1 7.4 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGF97822.1 - 3.5e-17 61.2 6.3 0.0036 16.8 0.3 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGF97822.1 - 6.7e-14 50.5 0.8 0.00034 20.1 0.1 6.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGF97822.1 - 1.3e-10 41.6 15.5 0.019 15.6 1.3 7.9 7 1 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGF97822.1 - 2.7e-10 39.5 3.4 0.31 11.3 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGF97822.1 - 3e-09 37.0 3.4 0.17 12.2 0.0 6.3 6 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGF97822.1 - 1.3e-08 34.6 18.5 2.5 8.9 0.0 9.6 8 3 3 11 11 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGF97822.1 - 2.7e-07 30.5 14.3 3.7 8.2 0.3 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGF97822.1 - 7.7e-07 28.4 7.1 2.4 8.1 0.2 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGF97822.1 - 1.9e-05 24.4 10.3 0.23 11.4 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGF97822.1 - 0.0027 17.5 12.7 0.0079 16.0 0.3 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EGF97822.1 - 1.6 9.4 6.9 30 5.4 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF998 PF06197.8 EGF97823.1 - 0.019 14.3 1.8 0.024 13.9 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) FliP PF00813.15 EGF97824.1 - 0.01 15.5 0.5 0.02 14.6 0.3 1.5 1 0 0 1 1 1 0 FliP family FAR1 PF03101.10 EGF97828.1 - 0.0014 19.0 0.0 0.0024 18.3 0.0 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain PGAP1 PF07819.8 EGF97831.1 - 0.00029 20.5 0.0 7.5 6.0 0.0 3.7 1 1 3 4 4 4 3 PGAP1-like protein WXG100 PF06013.7 EGF97831.1 - 0.00057 19.8 0.1 15 5.6 0.0 3.9 2 1 2 4 4 4 1 Proteins of 100 residues with WXG Spore_GerQ PF09671.5 EGF97831.1 - 0.039 13.5 0.0 44 3.8 0.0 3.6 2 1 2 4 4 4 0 Spore coat protein (Spore_GerQ) CHB_HEX_C PF03174.8 EGF97831.1 - 1.1 9.1 2.9 41 4.1 0.0 3.2 2 1 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Presenilin PF01080.12 EGF97834.1 - 3.9 6.1 4.9 4.7 5.9 3.4 1.1 1 0 0 1 1 1 0 Presenilin CytochromB561_N PF09786.4 EGF97834.1 - 5 5.4 10.6 6 5.1 7.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal MDFI PF15316.1 EGF97834.1 - 7.2 6.5 5.7 11 5.9 3.9 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Tim54 PF11711.3 EGF97837.1 - 0.025 13.1 3.5 0.51 8.8 0.2 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Mem_trans PF03547.13 EGF97837.1 - 3.8 5.7 10.0 1.7 6.8 4.1 1.9 2 0 0 2 2 2 0 Membrane transport protein DUF2606 PF10794.4 EGF97838.1 - 0.061 12.7 0.2 0.15 11.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2606) Mnd1 PF03962.10 EGF97838.1 - 0.23 11.0 8.7 1.1 8.9 2.8 2.4 2 0 0 2 2 2 0 Mnd1 family LRR_6 PF13516.1 EGF97839.1 - 4.2e-14 50.9 21.9 0.056 13.5 0.1 9.8 10 0 0 10 10 10 6 Leucine Rich repeat LRR_4 PF12799.2 EGF97839.1 - 3.9e-07 29.5 25.8 6.5e-05 22.4 0.5 6.9 5 2 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGF97839.1 - 0.0064 16.3 16.4 50 4.5 0.0 8.9 9 1 1 10 10 10 0 Leucine Rich Repeat LRR_8 PF13855.1 EGF97839.1 - 0.024 14.3 23.1 0.52 10.1 0.6 6.2 4 3 1 5 5 5 0 Leucine rich repeat Phage_head_fibr PF11133.3 EGF97839.1 - 0.041 13.0 0.2 0.073 12.2 0.1 1.3 1 0 0 1 1 1 0 Head fiber protein RdRP PF05183.7 EGF97840.1 - 8.5e-156 520.0 0.0 1.1e-155 519.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Hexokinase_2 PF03727.11 EGF97841.1 - 6.6e-84 280.9 0.0 8.9e-84 280.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EGF97841.1 - 8e-68 227.8 0.0 1.7e-67 226.7 0.0 1.5 2 0 0 2 2 2 1 Hexokinase DUF2779 PF11074.3 EGF97841.1 - 0.038 14.0 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) Lin-8 PF03353.10 EGF97841.1 - 0.12 11.6 0.6 0.17 11.0 0.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MFMR PF07777.6 EGF97843.1 - 3.6 7.4 11.2 4.6 7.1 7.7 1.3 1 1 0 1 1 1 0 G-box binding protein MFMR DEAD PF00270.24 EGF97845.1 - 9.9e-43 145.5 0.1 1.6e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGF97845.1 - 7.4e-22 77.0 0.0 1.5e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EGF97845.1 - 2.9e-19 68.3 0.1 6e-19 67.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) CLTH PF10607.4 EGF97846.1 - 6e-33 113.5 0.0 7.9e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EGF97846.1 - 9.5e-11 41.0 0.0 1.8e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 LisH Cyclin_N PF00134.18 EGF97847.1 - 0.054 13.0 1.2 0.23 11.0 0.7 2.1 1 1 0 1 1 1 0 Cyclin, N-terminal domain Cyt-b5 PF00173.23 EGF97850.1 - 0.00014 21.6 0.0 0.00026 20.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BRO1 PF03097.13 EGF97850.1 - 0.054 12.2 0.0 0.072 11.8 0.0 1.3 1 0 0 1 1 1 0 BRO1-like domain DUF1002 PF06207.6 EGF97850.1 - 0.2 10.9 1.3 0.36 10.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Pex14_N PF04695.8 EGF97850.1 - 0.75 9.8 9.8 0.37 10.8 1.2 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DnaJ PF00226.26 EGF97854.1 - 3.2e-14 52.4 0.1 6.3e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4231 PF14015.1 EGF97854.1 - 0.04 13.8 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Ndc1_Nup PF09531.5 EGF97855.1 - 0.28 9.5 1.1 0.31 9.3 0.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Init_tRNA_PT PF04179.7 EGF97856.1 - 1e-116 390.4 0.4 1.2e-116 390.2 0.3 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase PAT1 PF09770.4 EGF97859.1 - 2.5 6.2 13.9 2.8 6.0 9.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3818 PF12825.2 EGF97860.1 - 7.8e-117 389.7 0.0 1e-116 389.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EGF97860.1 - 5.1e-36 123.2 2.2 1.1e-35 122.2 1.5 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EGF97860.1 - 8.5e-09 35.2 0.2 3.9e-08 33.0 0.0 2.3 2 1 0 2 2 2 1 PX domain UPF0122 PF04297.9 EGF97862.1 - 0.0061 16.5 0.1 0.0099 15.8 0.0 1.3 1 1 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4_2 PF08281.7 EGF97862.1 - 0.0084 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 Baseplate_J PF04865.9 EGF97863.1 - 0.01 15.2 0.2 0.012 15.0 0.1 1.1 1 0 0 1 1 1 0 Baseplate J-like protein DUF1929 PF09118.6 EGF97864.1 - 0.12 12.4 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) RVT_3 PF13456.1 EGF97866.1 - 5.7e-08 32.4 0.8 1.4e-07 31.1 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase-like Ras PF00071.17 EGF97868.1 - 4.3e-43 146.4 0.0 5.7e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGF97868.1 - 1.4e-17 64.2 0.0 1.9e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGF97868.1 - 1.8e-10 40.3 0.0 6e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 EGF97868.1 - 1.2e-05 25.4 0.0 2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EGF97868.1 - 2.3e-05 23.8 0.0 6e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGF97868.1 - 0.00019 20.6 0.0 0.00037 19.7 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EGF97868.1 - 0.00067 19.6 0.1 0.0017 18.3 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 EGF97868.1 - 0.0021 18.0 0.0 0.0036 17.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGF97868.1 - 0.052 13.8 0.3 0.089 13.0 0.0 1.7 2 1 0 2 2 2 0 ABC transporter DUF258 PF03193.11 EGF97868.1 - 0.077 12.1 0.1 0.15 11.2 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGF97868.1 - 0.15 11.9 0.0 0.45 10.3 0.0 1.6 1 1 0 2 2 2 0 Dynamin family AAA_29 PF13555.1 EGF97868.1 - 0.35 10.4 0.0 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain TBP PF00352.16 EGF97874.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) DUF2312 PF10073.4 EGF97881.1 - 0.049 12.9 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Abhydrolase_6 PF12697.2 EGF97882.1 - 0.00065 19.6 0.0 0.0009 19.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_C65 PF10275.4 EGF97883.1 - 4e-05 23.1 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EGF97883.1 - 0.025 15.1 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 OTU-like cysteine protease DUF1845 PF08900.6 EGF97885.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) DUF4449 PF14613.1 EGF97885.1 - 1.5 8.7 5.6 0.17 11.8 0.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4449) Calmodulin_bind PF07887.6 EGF97887.1 - 0.075 12.0 0.1 0.16 10.9 0.0 1.5 2 0 0 2 2 2 0 Calmodulin binding protein-like DUF1843 PF08898.5 EGF97887.1 - 0.99 9.4 7.5 0.12 12.3 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Herpes_gI PF01688.12 EGF97889.1 - 0.082 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I SNF2_N PF00176.18 EGF97890.1 - 5.1e-38 130.5 0.8 5e-37 127.3 0.3 2.3 2 1 0 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.24 EGF97890.1 - 0.00081 18.9 0.0 0.0041 16.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Lectin_N PF03954.9 EGF97891.1 - 0.022 14.1 3.7 0.097 12.0 0.3 2.4 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Pro_dh PF01619.13 EGF97891.1 - 0.12 11.2 1.9 0.13 11.2 0.4 1.6 1 1 1 2 2 2 0 Proline dehydrogenase Syntaxin-6_N PF09177.6 EGF97892.1 - 0.00025 21.3 8.5 0.0056 17.0 2.8 2.4 1 1 1 2 2 2 2 Syntaxin 6, N-terminal Lebercilin PF15619.1 EGF97892.1 - 0.0042 16.5 7.9 0.0042 16.5 5.5 2.3 2 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DASH_Duo1 PF08651.5 EGF97892.1 - 0.01 15.3 5.7 9.9 5.8 0.3 3.5 2 2 1 3 3 3 0 DASH complex subunit Duo1 BLOC1_2 PF10046.4 EGF97892.1 - 0.061 13.4 10.8 0.8 9.8 3.3 2.9 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 EGF97892.1 - 0.071 12.9 6.1 0.56 10.0 2.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EGF97892.1 - 0.087 11.9 4.0 0.17 11.0 2.5 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF848 PF05852.6 EGF97892.1 - 0.22 11.3 10.7 0.086 12.6 5.1 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) NPV_P10 PF05531.7 EGF97892.1 - 0.38 11.0 7.0 9.4 6.5 0.8 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DivIVA PF05103.8 EGF97892.1 - 0.6 10.1 10.2 3.2 7.8 4.6 2.5 1 1 2 3 3 3 0 DivIVA protein Mnd1 PF03962.10 EGF97892.1 - 0.73 9.4 10.4 2.4 7.7 7.1 1.9 1 1 0 1 1 1 0 Mnd1 family DASH_Dam1 PF08653.5 EGF97892.1 - 0.87 9.4 5.1 20 5.0 1.2 3.2 2 1 0 2 2 2 0 DASH complex subunit Dam1 Fib_alpha PF08702.5 EGF97892.1 - 1.4 8.9 12.3 1.7 8.7 0.4 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3153 PF11353.3 EGF97892.1 - 1.6 8.1 6.9 6.9 6.0 4.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) DUF342 PF03961.8 EGF97892.1 - 1.6 7.0 9.6 6.2 5.1 6.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF948 PF06103.6 EGF97892.1 - 2.2 8.1 6.1 6.3 6.7 1.3 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) GrpE PF01025.14 EGF97892.1 - 2.9 7.4 9.3 9.5 5.7 3.5 2.2 1 1 1 2 2 2 0 GrpE DUF1664 PF07889.7 EGF97892.1 - 3.1 7.6 8.7 11 5.8 1.6 2.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 EGF97892.1 - 3.2 7.4 12.4 2 8.1 4.3 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 EMP24_GP25L PF01105.19 EGF97892.1 - 3.5 7.3 9.1 0.96 9.1 1.8 2.5 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD COG5 PF10392.4 EGF97892.1 - 4 7.3 10.5 2.6 8.0 3.6 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Syntaxin PF00804.20 EGF97892.1 - 4.2 7.5 13.8 3 8.0 4.2 2.4 1 1 1 2 2 2 0 Syntaxin XhlA PF10779.4 EGF97892.1 - 6.4 6.7 7.4 38 4.3 5.1 2.3 1 1 0 1 1 1 0 Haemolysin XhlA VLPT PF07122.6 EGF97894.1 - 0.099 12.3 0.8 0.17 11.5 0.5 1.4 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) DNA_pol_phi PF04931.8 EGF97895.1 - 0.84 7.3 12.6 0.023 12.5 4.2 1.6 2 0 0 2 2 2 0 DNA polymerase phi DASH_Spc34 PF08657.5 EGF97897.1 - 0.091 12.4 0.7 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Spc34 Prenyltrans PF00432.16 EGF97899.1 - 6.1e-20 70.4 18.6 4.2e-06 26.2 0.0 6.1 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGF97899.1 - 1.6e-16 60.7 0.0 6.4e-15 55.5 0.0 2.4 2 0 0 2 2 2 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGF97899.1 - 0.0018 18.2 0.0 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 Prenyltransferase-like SNF2_N PF00176.18 EGF97900.1 - 1.1e-42 145.9 3.5 1.2e-42 145.7 2.5 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGF97900.1 - 4.6e-08 32.7 0.0 5.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGF97900.1 - 0.00076 19.3 0.1 0.0011 18.8 0.1 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGF97901.1 - 7.5e-12 44.9 0.0 1.3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ima1_N PF09779.4 EGF97902.1 - 4.7e-12 46.5 3.2 4.6e-11 43.3 2.2 2.3 1 1 0 1 1 1 1 Ima1 N-terminal domain Benyvirus_14KDa PF07255.6 EGF97902.1 - 0.046 13.6 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Benyvirus 14KDa protein Epimerase PF01370.16 EGF97903.1 - 3.5e-11 42.9 0.0 4.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGF97903.1 - 2.5e-10 39.5 0.0 3.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGF97903.1 - 2.1e-07 31.1 0.0 5.1e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGF97903.1 - 6.3e-06 25.3 0.0 1.5e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EGF97903.1 - 5.5e-05 22.2 0.0 0.0001 21.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EGF97903.1 - 8.8e-05 21.8 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EGF97903.1 - 0.00078 19.3 0.0 0.003 17.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase polyprenyl_synt PF00348.12 EGF97904.1 - 4.2e-35 120.8 0.0 5.2e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase eIF3_subunit PF08597.5 EGF97905.1 - 0.063 12.8 6.2 0.074 12.6 4.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF572 PF04502.8 EGF97905.1 - 1.4 8.0 13.0 1.7 7.7 9.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) NAD_binding_10 PF13460.1 EGF97907.1 - 6.5e-10 39.2 0.1 0.0012 18.8 0.1 2.8 2 1 0 2 2 2 2 NADH(P)-binding Epimerase PF01370.16 EGF97907.1 - 1.1e-09 38.1 0.0 3e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGF97907.1 - 7e-09 34.9 0.0 2.7e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EGF97907.1 - 3.4e-07 29.2 0.0 9.9e-07 27.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGF97907.1 - 0.00059 19.7 0.0 0.0017 18.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EGF97907.1 - 0.031 13.5 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.7 EGF97908.1 - 2.2e-06 26.7 0.0 2.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGF97908.1 - 5.5e-05 23.2 0.0 0.00049 20.1 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGF97908.1 - 0.00031 20.2 0.0 0.00057 19.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MARVEL PF01284.18 EGF97909.1 - 1.4e-10 41.1 14.0 1.5e-10 41.0 9.1 1.5 1 1 0 1 1 1 1 Membrane-associating domain RAP1 PF07218.6 EGF97916.1 - 0.88 7.5 7.0 1.1 7.3 4.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pol_alpha_B_N PF08418.5 EGF97916.1 - 2.8 7.4 11.1 3.1 7.2 7.7 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal P_C PF06640.6 EGF97916.1 - 6.6 6.6 12.2 9.9 6.0 8.0 1.5 1 1 0 1 1 1 0 P protein C-terminus zf-TAZ PF02135.11 EGF97917.1 - 0.0051 16.8 3.8 0.0069 16.3 2.6 1.2 1 0 0 1 1 1 1 TAZ zinc finger zf-C2H2 PF00096.21 EGF97917.1 - 0.037 14.3 8.1 0.039 14.2 1.4 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGF97917.1 - 0.19 12.1 6.8 0.27 11.6 1.5 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger PyrI_C PF02748.10 EGF97917.1 - 0.19 11.1 0.8 0.31 10.4 0.5 1.5 1 1 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_Tnp_IS1 PF03811.8 EGF97917.1 - 0.22 11.0 3.8 0.65 9.5 2.5 1.9 1 1 0 1 1 1 0 InsA N-terminal domain Med7 PF05983.6 EGF97918.1 - 1.3e-10 41.2 1.0 6.6e-08 32.5 0.2 2.2 1 1 1 2 2 2 2 MED7 protein Glyco_hydro_47 PF01532.15 EGF97922.1 - 6.2e-09 35.0 0.0 7.2e-09 34.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 NAD_Gly3P_dh_N PF01210.18 EGF97922.1 - 0.084 12.6 0.0 0.098 12.3 0.0 1.1 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus WD40 PF00400.27 EGF97923.1 - 6.3e-07 29.0 2.5 0.0075 16.1 0.0 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat NAD_binding_10 PF13460.1 EGF97924.1 - 3.4e-07 30.4 0.0 8.9e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGF97924.1 - 4.6e-06 26.2 0.1 0.074 12.4 0.0 2.5 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGF97924.1 - 0.00013 20.8 0.0 0.00047 18.9 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGF97924.1 - 0.0061 15.5 0.0 0.0098 14.8 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EGF97924.1 - 0.025 14.5 0.1 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 EGF97924.1 - 0.077 12.6 0.0 0.51 9.9 0.0 2.1 1 1 1 2 2 2 0 KR domain NmrA PF05368.8 EGF97924.1 - 0.098 11.8 0.0 0.42 9.8 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Epimerase PF01370.16 EGF97925.1 - 9.3e-14 51.4 0.0 1.4e-13 50.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGF97925.1 - 9.2e-13 47.5 0.0 1.4e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGF97925.1 - 4.1e-10 39.0 0.0 1e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGF97925.1 - 4.8e-10 39.7 0.0 1.1e-09 38.5 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGF97925.1 - 2.9e-05 23.4 0.0 4.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EGF97925.1 - 5e-05 23.2 0.0 0.0002 21.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGF97925.1 - 0.0075 15.9 0.0 0.033 13.8 0.0 1.9 1 1 0 1 1 1 1 KR domain Sigma54_activ_2 PF14532.1 EGF97925.1 - 0.065 13.2 0.0 0.36 10.8 0.0 2.2 2 1 1 3 3 3 0 Sigma-54 interaction domain PRO8NT PF08082.6 EGF97926.1 - 1.7e-50 170.6 0.4 2e-50 170.3 0.3 1.1 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain PROCN PF08083.6 EGF97926.1 - 0.002 16.6 0.1 0.0021 16.5 0.0 1.2 1 0 0 1 1 1 1 PROCN (NUC071) domain Pox_Ag35 PF03286.9 EGF97927.1 - 0.065 12.7 2.7 0.13 11.7 1.9 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Curto_V2 PF07325.6 EGF97927.1 - 2.1 8.0 5.2 3.8 7.1 3.6 1.4 1 0 0 1 1 1 0 Curtovirus V2 protein DUF3835 PF12927.2 EGF97928.1 - 9.7e-05 23.2 0.0 9.7e-05 23.2 0.0 6.7 4 3 1 5 5 5 1 Domain of unknown function (DUF3835) Malate_DH PF12434.3 EGF97928.1 - 0.13 11.9 1.9 0.28 10.9 0.1 2.6 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Myc_N PF01056.13 EGF97929.1 - 0.3 10.2 12.6 0.027 13.6 4.1 2.1 2 0 0 2 2 2 0 Myc amino-terminal region Brevenin PF03032.10 EGF97929.1 - 1.1 9.1 8.2 2.9 7.8 5.7 1.6 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family Pheromone PF08015.6 EGF97929.1 - 1.3 9.9 18.2 5.5 7.8 5.9 2.7 2 1 0 2 2 2 0 Fungal mating-type pheromone UTP15_C PF09384.5 EGF97933.1 - 0.043 13.5 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 UTP15 C terminal SNF2_N PF00176.18 EGF97934.1 - 1.9e-72 243.5 2.1 3.3e-72 242.8 0.1 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.1 EGF97934.1 - 1.8e-07 31.0 8.6 4.2e-07 29.8 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGF97934.1 - 2.5e-07 30.2 7.8 5.4e-07 29.1 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGF97934.1 - 1.6e-06 27.8 8.7 4e-06 26.5 6.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EGF97934.1 - 3e-06 26.9 7.9 2.3e-05 24.0 5.7 2.2 1 1 1 2 2 2 1 Ring finger domain ResIII PF04851.10 EGF97934.1 - 8.5e-06 25.7 0.2 3e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 EGF97934.1 - 3.2e-05 23.5 6.3 5.8e-05 22.6 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGF97934.1 - 0.00025 20.7 7.4 0.00049 19.7 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain HIRAN PF08797.6 EGF97934.1 - 0.0011 18.9 0.0 0.0039 17.0 0.0 1.9 2 0 0 2 2 2 1 HIRAN domain zf-RING_UBOX PF13445.1 EGF97934.1 - 0.0034 17.0 3.2 0.012 15.3 2.2 2.0 1 0 0 1 1 1 1 RING-type zinc-finger CAF-1_p150 PF11600.3 EGF97935.1 - 0.016 14.5 7.8 0.027 13.8 5.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UPF0560 PF10577.4 EGF97935.1 - 0.052 11.8 1.1 0.074 11.2 0.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hexapep PF00132.19 EGF97937.1 - 1.8e-08 33.5 6.7 0.0088 15.5 0.1 3.7 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EGF97937.1 - 4.4e-05 22.9 0.0 7.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.7 EGF97937.1 - 0.0038 15.8 1.1 0.024 13.2 0.8 2.0 1 1 1 2 2 2 2 L-fucokinase CTP_transf_3 PF02348.14 EGF97937.1 - 0.025 14.2 0.1 0.069 12.7 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase NTP_transf_3 PF12804.2 EGF97937.1 - 0.11 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain HAP2-GCS1 PF10699.4 EGF97938.1 - 0.1 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Male gamete fusion factor MutS_III PF05192.13 EGF97938.1 - 0.12 12.1 0.9 0.15 11.8 0.6 1.1 1 0 0 1 1 1 0 MutS domain III DUF3129 PF11327.3 EGF97939.1 - 2.5e-19 69.7 0.0 5.8e-19 68.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3129) Pkinase PF00069.20 EGF97941.1 - 6e-56 189.4 0.0 7.5e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF97941.1 - 2.1e-20 72.8 0.0 3.4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGF97941.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.11 EGF97941.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 ABC1 family RVT_3 PF13456.1 EGF97942.1 - 2.3e-05 24.0 0.1 5.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like Kinetochor_Ybp2 PF08568.5 EGF97944.1 - 4.7e-09 35.0 0.3 0.00048 18.5 0.0 2.3 2 1 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin WD40 PF00400.27 EGF97946.1 - 4.5e-08 32.6 3.0 2.7e-06 27.0 1.5 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat SBP56 PF05694.6 EGF97946.1 - 0.046 12.2 0.1 0.64 8.4 0.0 2.2 2 1 0 2 2 2 0 56kDa selenium binding protein (SBP56) FtsJ PF01728.14 EGF97947.1 - 2e-66 223.4 0.0 3.4e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EGF97947.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CbiA PF01656.18 EGF97947.1 - 0.13 11.6 0.1 0.3 10.4 0.1 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FAM176 PF14851.1 EGF97948.1 - 0.2 11.2 1.9 0.47 10.1 1.3 1.7 1 0 0 1 1 1 0 FAM176 family Nucleo_P87 PF07267.6 EGF97948.1 - 3.3 6.2 6.3 5.7 5.4 4.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAR1 PF03101.10 EGF97949.1 - 0.068 13.7 2.7 0.14 12.7 0.1 2.2 2 0 0 2 2 2 0 FAR1 DNA-binding domain AFT PF08731.6 EGF97949.1 - 1 9.5 3.4 1.8 8.8 0.2 2.3 2 0 0 2 2 2 0 Transcription factor AFT HALZ PF02183.13 EGF97950.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper zf-met PF12874.2 EGF97951.1 - 2 8.7 24.2 40 4.5 0.0 7.6 2 2 6 8 8 8 0 Zinc-finger of C2H2 type SUI1 PF01253.17 EGF97952.1 - 2.5e-28 97.7 0.1 3e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 RRM_1 PF00076.17 EGF97953.1 - 0.0027 17.2 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGF97953.1 - 0.0036 17.2 0.0 0.0069 16.3 0.0 1.4 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGF97953.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAPPC-Trs85 PF12739.2 EGF97954.1 - 5.5e-59 199.8 0.5 7.7e-59 199.3 0.4 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.1 EGF97954.1 - 0.13 11.4 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP PAP2 PF01569.16 EGF97955.1 - 2.4e-13 49.8 8.5 4.9e-13 48.8 5.9 1.6 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 EGF97955.1 - 0.00063 19.4 0.3 0.18 11.5 0.0 2.4 2 0 0 2 2 2 2 Divergent PAP2 family DUF2649 PF10854.3 EGF97955.1 - 6.2 7.0 7.5 0.36 10.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) RecR PF02132.10 EGF97956.1 - 0.049 13.0 1.1 0.049 13.0 0.8 1.6 2 0 0 2 2 2 0 RecR protein RecR PF02132.10 EGF97957.1 - 0.049 13.0 1.1 0.049 13.0 0.8 1.6 2 0 0 2 2 2 0 RecR protein Mgr1 PF08602.5 EGF97960.1 - 0.16 10.9 7.9 0.15 11.0 4.3 1.7 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit LRS4 PF10422.4 EGF97962.1 - 0.00055 19.3 2.1 0.00066 19.1 1.5 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Mod_r PF07200.8 EGF97962.1 - 0.021 14.7 2.0 0.022 14.6 1.4 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF1423 PF07227.6 EGF97962.1 - 0.028 13.1 0.5 0.032 12.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DUF641 PF04859.7 EGF97962.1 - 0.068 12.9 3.2 0.078 12.7 2.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) MerR-DNA-bind PF09278.6 EGF97962.1 - 0.093 13.1 1.9 0.12 12.8 0.6 1.7 1 1 0 1 1 1 0 MerR, DNA binding IncA PF04156.9 EGF97962.1 - 0.49 9.9 3.3 0.53 9.8 2.3 1.1 1 0 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 EGF97962.1 - 0.88 9.3 7.1 1.5 8.5 4.9 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Lge1 PF11488.3 EGF97962.1 - 1.7 8.9 6.4 2.3 8.4 4.5 1.3 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Fer2 PF00111.22 EGF97963.1 - 4e-07 29.6 0.2 6.1e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1727 PF08353.5 EGF97963.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) Galactosyl_T PF01762.16 EGF97964.1 - 2.3e-09 37.1 0.0 0.004 16.7 0.0 3.3 2 1 1 3 3 3 3 Galactosyltransferase DUF3357 PF11837.3 EGF97964.1 - 0.057 13.2 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Abhydrolase_2 PF02230.11 EGF97965.1 - 1.1e-27 96.9 0.0 1.5e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGF97965.1 - 2.1e-06 27.5 0.0 4.4e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGF97965.1 - 4.8e-05 23.3 0.0 0.00012 22.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGF97965.1 - 0.0031 16.9 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) RRM_1 PF00076.17 EGF97966.1 - 2.4e-41 139.1 0.2 5.7e-18 64.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGF97966.1 - 1.4e-27 95.4 0.4 8.8e-11 41.6 0.1 3.7 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGF97966.1 - 2.5e-21 75.2 0.3 3.8e-09 36.2 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EGF97966.1 - 5.5e-19 68.2 0.1 1.8e-18 66.5 0.1 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 EGF97966.1 - 1.9e-05 24.4 1.7 0.002 17.9 0.1 3.8 3 1 0 3 3 3 1 RNA binding motif Utp11 PF03998.8 EGF97972.1 - 0.0074 16.1 0.2 0.009 15.8 0.1 1.1 1 0 0 1 1 1 1 Utp11 protein Gyro_capsid PF04162.7 EGF97972.1 - 0.032 12.4 0.1 0.038 12.2 0.1 1.1 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) SNF2_N PF00176.18 EGF97974.1 - 2.3e-60 203.9 1.9 3.1e-60 203.4 0.4 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGF97974.1 - 1.1e-10 41.1 0.1 3.1e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGF97974.1 - 1.4e-05 24.6 0.0 7.3e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 EGF97974.1 - 0.086 12.3 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol_phi PF04931.8 EGF97975.1 - 0.071 10.8 8.0 0.17 9.5 5.5 1.6 1 0 0 1 1 1 0 DNA polymerase phi MMR_HSR1 PF01926.18 EGF97985.1 - 2.3e-11 43.6 0.0 4.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGF97985.1 - 4.2e-05 22.8 0.0 9.5e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EGF97985.1 - 0.043 14.3 0.1 0.21 12.0 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EGF97985.1 - 0.067 12.3 0.0 0.62 9.2 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGF97985.1 - 0.08 12.7 0.0 3.5 7.4 0.0 2.6 1 1 1 2 2 2 0 Dynamin family Tox-MPTase3 PF15639.1 EGF97986.1 - 0.0078 15.9 0.2 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase toxin 3 Lipase_GDSL PF00657.17 EGF97988.1 - 0.0003 20.6 0.0 0.00036 20.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EGF97988.1 - 0.0018 18.4 0.0 0.0025 17.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Herpes_UL45 PF05473.7 EGF97989.1 - 1.9 7.8 6.4 1.1 8.6 0.7 2.6 1 1 1 2 2 2 0 UL45 protein DUF1067 PF06362.6 EGF97992.1 - 0.18 12.3 2.1 0.28 11.7 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1067) SART-1 PF03343.8 EGF97994.1 - 0.96 7.7 24.6 0.55 8.5 9.3 2.1 1 1 1 2 2 2 0 SART-1 family Sad1_UNC PF07738.8 EGF97995.1 - 2.9e-27 95.0 0.0 5e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RhoGEF PF00621.15 EGF97995.1 - 0.047 13.5 0.1 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 RhoGEF domain Epsilon_antitox PF08998.6 EGF97995.1 - 0.052 13.5 0.4 0.19 11.7 0.1 2.0 2 0 0 2 2 2 0 Bacterial epsilon antitoxin NPV_P10 PF05531.7 EGF97995.1 - 0.15 12.2 0.9 0.52 10.6 0.6 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1399 PF07173.7 EGF97996.1 - 0.048 13.9 0.6 3.2 8.0 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1399) Transket_pyr PF02779.19 EGF97997.1 - 0.0011 18.4 0.0 0.0036 16.8 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain IncA PF04156.9 EGF98001.1 - 0.03 13.9 4.8 0.052 13.1 3.3 1.4 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 EGF98001.1 - 0.049 12.2 6.7 0.078 11.6 4.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Bap31 PF05529.7 EGF98001.1 - 0.082 12.3 2.9 0.16 11.4 2.0 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF2203 PF09969.4 EGF98001.1 - 0.098 12.8 2.8 0.21 11.8 2.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Phage_fiber_2 PF03406.8 EGF98002.1 - 0.022 14.3 0.3 0.078 12.6 0.2 1.9 1 0 0 1 1 1 0 Phage tail fibre repeat DUF3597 PF12200.3 EGF98002.1 - 1.2 9.5 4.1 0.61 10.4 0.2 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF3597) SNF2_N PF00176.18 EGF98003.1 - 4.9e-30 104.3 0.1 6.4e-30 103.9 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGF98003.1 - 0.00012 21.6 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGF98004.1 - 2.7e-11 43.1 0.0 3.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sigma70_ner PF04546.8 EGF98006.1 - 0.0057 16.2 4.4 0.16 11.5 0.6 2.2 2 0 0 2 2 2 2 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EGF98006.1 - 0.032 13.7 8.3 0.25 10.8 3.9 2.2 2 0 0 2 2 2 0 Nucleoplasmin RXT2_N PF08595.6 EGF98006.1 - 0.29 10.9 11.3 0.11 12.3 4.3 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.7 EGF98006.1 - 0.6 9.7 12.1 0.14 11.8 4.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.5 EGF98006.1 - 1.2 9.4 16.3 18 5.6 7.6 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 EGF98006.1 - 5.3 7.2 12.7 1.5 9.0 2.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF551 PF04448.7 EGF98006.1 - 8.7 7.1 8.8 0.37 11.5 0.2 3.0 3 2 0 3 3 3 0 Protein of unknown function (DUF551) Histone PF00125.19 EGF98007.1 - 4.1e-14 52.4 0.1 5e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGF98007.1 - 3.8e-05 23.7 0.0 5e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EGF98007.1 - 0.00011 22.0 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EGF98007.1 - 0.0013 18.7 0.1 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGF98007.1 - 0.047 12.9 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T ECM11 PF15463.1 EGF98009.1 - 0.19 12.0 3.4 0.2 11.9 0.1 2.3 2 0 0 2 2 2 0 Extracellular mutant protein 11 Glyco_transf_28 PF03033.15 EGF98010.1 - 5.8e-22 77.9 0.0 1.4e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EGF98010.1 - 0.00047 18.8 0.0 0.0012 17.5 0.0 1.6 2 1 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase HypD PF01924.11 EGF98010.1 - 0.16 10.6 0.1 0.35 9.5 0.0 1.5 2 0 0 2 2 2 0 Hydrogenase formation hypA family GTP_EFTU PF00009.22 EGF98011.1 - 1e-21 77.2 0.0 2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGF98011.1 - 1.3e-17 63.7 0.2 5.1e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGF98011.1 - 1.7e-08 34.4 1.1 1.7e-08 34.4 0.7 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EGF98011.1 - 0.00062 19.3 3.7 0.0029 17.1 1.2 3.0 2 1 0 2 2 2 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 EGF98011.1 - 0.0027 17.1 0.2 0.6 9.6 0.0 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Alpha_kinase PF02816.13 EGF98012.1 - 0.016 14.8 4.9 0.04 13.5 3.4 1.9 1 1 0 1 1 1 0 Alpha-kinase family zf-CCHC PF00098.18 EGF98013.1 - 0.059 13.3 1.1 0.096 12.6 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Alpha_kinase PF02816.13 EGF98016.1 - 0.019 14.6 0.1 0.033 13.8 0.1 1.5 1 1 0 1 1 1 0 Alpha-kinase family DUF177 PF02620.12 EGF98017.1 - 0.01 15.9 0.2 0.018 15.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, COG1399 zf-CCHC PF00098.18 EGF98017.1 - 0.02 14.7 0.3 0.043 13.7 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Podoplanin PF05808.6 EGF98017.1 - 1.2 8.6 6.8 1.7 8.2 4.5 1.4 1 1 0 1 1 1 0 Podoplanin SURF2 PF05477.6 EGF98018.1 - 0.03 13.4 2.6 0.072 12.2 1.8 1.6 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Pdase_C33_assoc PF14756.1 EGF98020.1 - 0.017 14.8 0.2 0.033 13.8 0.1 1.4 1 1 0 1 1 1 0 Peptidase_C33-associated domain zf-CCHC_2 PF13696.1 EGF98022.1 - 0.0067 15.8 0.8 0.017 14.6 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGF98022.1 - 0.17 11.5 0.7 0.33 10.6 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle FAR1 PF03101.10 EGF98027.1 - 0.02 15.3 0.0 0.02 15.3 0.0 2.6 3 1 0 3 3 3 0 FAR1 DNA-binding domain Pescadillo_N PF06732.6 EGF98027.1 - 0.49 9.6 2.4 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Pescadillo N-terminus GCM PF03615.10 EGF98028.1 - 0.015 14.8 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 GCM motif protein GAGA_bind PF06217.7 EGF98029.1 - 2.5 8.0 9.6 3.2 7.6 6.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Sugar_tr PF00083.19 EGF98032.1 - 7.1e-36 123.7 23.6 2.2e-26 92.4 4.1 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGF98032.1 - 8.8e-35 120.0 57.9 1.7e-31 109.2 22.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGF98032.1 - 0.0008 19.1 1.0 0.25 11.1 0.1 2.9 2 1 0 2 2 2 2 MFS_1 like family ESSS PF10183.4 EGF98032.1 - 0.053 13.9 0.2 0.27 11.6 0.0 2.3 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) V-SNARE PF05008.10 EGF98033.1 - 0.0052 16.9 2.6 0.018 15.2 1.8 1.9 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus DUF4071 PF13281.1 EGF98033.1 - 0.25 10.1 2.3 0.44 9.3 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) GST_N_3 PF13417.1 EGF98034.1 - 4.1e-11 42.9 0.0 6.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGF98034.1 - 6.4e-11 42.1 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGF98034.1 - 2.5e-07 30.7 0.0 1.3e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGF98034.1 - 2.9e-07 30.3 0.1 9.4e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Histone PF00125.19 EGF98036.1 - 5.4e-31 106.5 0.4 8.6e-31 105.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGF98036.1 - 7.9e-05 22.7 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGF98036.1 - 0.002 18.1 0.1 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PRAI PF00697.17 EGF98036.1 - 0.053 13.0 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Bromo_TP PF07524.8 EGF98036.1 - 0.056 13.1 0.1 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 EGF98036.1 - 0.11 12.2 0.2 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Prenyltrans PF00432.16 EGF98037.1 - 5.4e-23 80.2 15.0 1.7e-05 24.2 0.0 6.1 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGF98037.1 - 5.6e-17 62.1 0.0 4.3e-15 56.0 0.0 2.8 3 0 0 3 3 3 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGF98037.1 - 0.0057 16.6 0.0 0.052 13.5 0.0 2.3 1 1 1 2 2 2 1 Prenyltransferase-like Polysacc_syn_2C PF08485.5 EGF98038.1 - 0.03 13.8 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal F-box-like PF12937.2 EGF98038.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 F-box-like Glyco_hydro_47 PF01532.15 EGF98039.1 - 2.1e-07 30.0 0.1 5.6e-07 28.5 0.0 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 47 BSP_II PF05432.6 EGF98041.1 - 0.16 11.1 7.7 0.51 9.5 5.2 1.8 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pro_isomerase PF00160.16 EGF98042.1 - 5.3e-30 104.6 0.1 5.7e-30 104.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Equine_IAV_S2 PF06502.6 EGF98045.1 - 0.027 14.3 2.1 6.5 6.6 0.0 3.7 1 1 4 5 5 5 0 Equine infectious anaemia virus S2 protein DUF3454 PF11936.3 EGF98045.1 - 2.5 8.3 25.2 75 3.6 13.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF3454) Reductase_C PF14759.1 EGF98046.1 - 0.11 12.8 0.0 0.41 10.9 0.0 2.0 2 0 0 2 2 2 0 Reductase C-terminal Mucin PF01456.12 EGF98046.1 - 6.1 6.6 14.5 14 5.4 10.0 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Ebola_NP PF05505.7 EGF98052.1 - 0.00043 18.5 7.7 0.00046 18.4 5.3 1.0 1 0 0 1 1 1 1 Ebola nucleoprotein tRNA_Me_trans PF03054.11 EGF98052.1 - 0.12 10.8 0.1 0.2 10.1 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase NESP55 PF06390.7 EGF98052.1 - 0.56 9.5 13.3 0.54 9.5 5.8 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Dor1 PF04124.7 EGF98053.1 - 7.7e-08 31.1 0.1 8.8e-07 27.6 0.1 2.0 1 1 0 1 1 1 1 Dor1-like family DNA_primase_S PF01896.14 EGF98054.1 - 4.5e-13 49.2 6.3 5.5e-06 26.2 0.1 2.6 2 1 1 3 3 3 2 Eukaryotic and archaeal DNA primase small subunit AA_permease PF00324.16 EGF98055.1 - 2.9e-109 365.5 44.3 3.5e-109 365.3 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGF98055.1 - 9.8e-32 110.0 44.8 1.3e-31 109.6 31.0 1.2 1 0 0 1 1 1 1 Amino acid permease Myb_DNA-bind_3 PF12776.2 EGF98057.1 - 2.6e-13 50.4 2.6 8.1e-13 48.8 1.8 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Daxx PF03344.10 EGF98057.1 - 0.028 12.9 33.6 0.019 13.4 13.2 2.1 2 0 0 2 2 2 0 Daxx Family ALF PF03752.8 EGF98057.1 - 0.25 11.2 2.0 2.8 7.8 0.4 2.6 2 0 0 2 2 2 0 Short repeats of unknown function CAP_N PF01213.14 EGF98058.1 - 4.7 6.4 8.1 0.14 11.4 1.2 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.20 EGF98059.1 - 2.8e-47 161.0 0.0 4.6e-47 160.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF98059.1 - 7.4e-18 64.5 0.0 3.2e-17 62.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGF98059.1 - 1.1e-07 31.0 0.0 2.9e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGF98059.1 - 0.0042 16.1 0.0 0.0061 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGF98059.1 - 0.0057 16.4 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EGF98059.1 - 0.038 12.7 0.2 0.057 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GluR_Homer-bdg PF10606.4 EGF98059.1 - 0.097 12.5 0.1 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Homer-binding domain of metabotropic glutamate receptor NMT PF01233.14 EGF98062.1 - 1.8e-72 242.2 0.0 3e-72 241.5 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EGF98062.1 - 5.2e-63 211.8 0.0 7.9e-63 211.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_7 PF13508.1 EGF98062.1 - 0.051 13.7 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HGTP_anticodon2 PF12745.2 EGF98062.1 - 0.11 11.5 1.3 0.19 10.8 0.9 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF1533 PF07550.6 EGF98064.1 - 0.12 12.4 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) Adap_comp_sub PF00928.16 EGF98066.1 - 3e-38 131.4 0.0 4.9e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGF98066.1 - 0.00039 20.1 0.2 0.00067 19.3 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2340 PF10209.4 EGF98066.1 - 0.0013 18.8 0.0 0.0035 17.4 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) MAM PF00629.18 EGF98066.1 - 0.014 15.1 0.1 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 MAM domain Toxin_27 PF08099.6 EGF98068.1 - 0.032 14.1 0.3 0.032 14.1 0.2 1.7 2 0 0 2 2 2 0 Scorpion calcine family HSP20 PF00011.16 EGF98070.1 - 7.4e-15 54.6 0.3 7.9e-15 54.5 0.2 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4454 PF14628.1 EGF98070.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) Bromodomain PF00439.20 EGF98071.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Bromodomain DHC_N2 PF08393.8 EGF98072.1 - 0.026 13.0 0.2 0.026 13.0 0.1 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 RCSD PF05177.7 EGF98073.1 - 0.0016 18.8 0.4 0.0042 17.5 0.3 1.8 1 0 0 1 1 1 1 RCSD region Transketolase_N PF00456.16 EGF98075.1 - 1.8e-18 66.4 0.5 2e-17 63.0 0.3 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 EGF98075.1 - 7.5e-09 35.5 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 EGF98075.1 - 1.8e-06 27.5 0.1 3.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 EGF98075.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ACOX PF01756.14 EGF98076.1 - 1.3e-48 164.9 0.2 3.6e-48 163.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EGF98076.1 - 6.1e-14 51.2 1.9 1.4e-13 50.1 0.3 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EGF98076.1 - 1e-11 45.2 0.7 5.4e-11 42.8 0.0 2.4 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 EGF98076.1 - 2.5e-07 30.9 2.1 1.6e-06 28.2 0.9 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain ADH_N PF08240.7 EGF98077.1 - 8e-28 96.3 0.8 8e-28 96.3 0.6 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGF98077.1 - 9.3e-13 47.8 0.1 3e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EGF98077.1 - 0.00042 19.9 0.0 0.0011 18.5 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 EGF98077.1 - 0.012 14.7 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EGF98077.1 - 0.096 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 EGF98077.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 EGF98077.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Dict-STAT-coil PF09267.5 EGF98078.1 - 0.1 12.7 0.2 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil DUF1533 PF07550.6 EGF98079.1 - 0.1 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) JmjC PF02373.17 EGF98085.1 - 1.2e-07 31.9 0.2 1.6e-07 31.5 0.2 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 EGF98085.1 - 0.044 13.0 0.0 0.044 13.0 0.0 1.0 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_8 PF13621.1 EGF98085.1 - 0.062 12.7 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 Cupin-like domain Cupin_2 PF07883.6 EGF98085.1 - 0.075 12.5 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Cupin domain Epimerase PF01370.16 EGF98086.1 - 6.4e-48 163.2 0.0 8.7e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGF98086.1 - 0.00037 19.4 0.2 0.02 13.7 0.2 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGF98086.1 - 0.0017 17.2 0.0 0.0047 15.8 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Glyco_transf_28 PF03033.15 EGF98087.1 - 1.9e-13 50.3 0.0 2.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain CBM_5_12_2 PF14600.1 EGF98088.1 - 0.0072 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Cellulose-binding domain CPSF_A PF03178.10 EGF98089.1 - 1.6e-61 208.2 0.0 9.7e-41 139.8 0.0 3.3 3 0 0 3 3 3 2 CPSF A subunit region LRR_4 PF12799.2 EGF98090.1 - 9e-08 31.5 6.1 1.6e-06 27.5 3.1 2.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) TAP_C PF03943.8 EGF98090.1 - 4.3e-07 29.2 0.0 7.8e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.1 EGF98090.1 - 0.00034 20.0 0.1 0.0011 18.4 0.1 1.9 1 0 0 1 1 1 1 UBA-like domain NTF2 PF02136.15 EGF98090.1 - 0.0022 18.3 0.0 0.0082 16.5 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.1 EGF98090.1 - 0.0031 17.2 5.0 0.015 14.9 1.1 3.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_7 PF13504.1 EGF98090.1 - 0.13 12.5 1.3 1.2e+02 3.6 0.0 4.1 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 EGF98090.1 - 3.8 7.9 11.4 17 5.9 0.8 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat NGP1NT PF08153.7 EGF98093.1 - 9.7e-44 148.4 0.6 2.4e-43 147.2 0.0 1.9 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EGF98093.1 - 4.1e-21 75.0 0.0 1.7e-16 60.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EGF98093.1 - 1.1e-06 27.9 0.0 0.00012 21.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EGF98093.1 - 0.00036 19.7 0.0 0.00076 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 EGF98093.1 - 0.023 13.9 0.0 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.18 EGF98093.1 - 0.048 13.4 4.8 2.2 8.0 0.0 3.9 3 1 1 4 4 4 0 Dynamin family DUF1754 PF08555.5 EGF98095.1 - 0.0091 16.5 2.6 0.02 15.5 1.8 1.5 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) NST1 PF13945.1 EGF98095.1 - 1.5 8.8 8.5 0.13 12.3 1.3 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator zf-rbx1 PF12678.2 EGF98096.1 - 0.047 13.7 1.2 0.24 11.5 0.3 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_2 PF13639.1 EGF98096.1 - 0.094 12.5 2.5 0.22 11.3 0.2 2.7 2 0 0 2 2 2 0 Ring finger domain DUF4027 PF13219.1 EGF98097.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) NIF PF03031.13 EGF98098.1 - 2.4e-16 59.8 0.0 5.6e-16 58.6 0.0 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 EGF98098.1 - 0.0053 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Y_phosphatase PF00102.22 EGF98100.1 - 3.6e-15 55.9 0.1 4.2e-08 32.8 0.0 2.0 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 EGF98100.1 - 0.00046 19.7 0.3 0.0011 18.5 0.1 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EGF98100.1 - 0.0035 17.6 0.1 0.006 16.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EGF98100.1 - 0.02 14.9 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 EGF98100.1 - 0.03 13.7 0.2 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PIG-L PF02585.12 EGF98104.1 - 1.2e-22 80.8 0.0 1.7e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase PYST-C1 PF09690.5 EGF98105.1 - 1.6 8.4 7.4 24 4.6 5.1 2.4 1 1 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) HTH_Tnp_4 PF13613.1 EGF98106.1 - 0.034 13.6 0.0 0.097 12.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CFEM PF05730.6 EGF98109.1 - 9.5e-14 50.9 6.9 1.1e-13 50.7 4.8 1.1 1 0 0 1 1 1 1 CFEM domain Metallothio PF00131.15 EGF98109.1 - 0.74 9.7 4.8 17 5.3 0.4 2.2 1 1 1 2 2 2 0 Metallothionein DNA_ligase_A_M PF01068.16 EGF98110.1 - 1.1e-56 191.4 4.2 1.5e-56 190.9 2.9 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGF98110.1 - 1.6e-55 187.6 0.1 2.8e-55 186.8 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGF98110.1 - 7.5e-23 80.7 0.0 2e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EGF98110.1 - 0.06 13.0 0.5 1 9.1 0.0 2.6 3 0 0 3 3 3 0 DNA ligase OB-like domain HeH PF12949.2 EGF98112.1 - 0.01 15.3 0.1 0.028 13.9 0.1 1.7 1 1 0 1 1 1 0 HeH/LEM domain DJ-1_PfpI PF01965.19 EGF98114.1 - 0.05 13.0 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Nodulin_late PF07127.6 EGF98114.1 - 0.11 12.6 0.4 0.21 11.7 0.3 1.4 1 0 0 1 1 1 0 Late nodulin protein ECH PF00378.15 EGF98115.1 - 1.4e-29 102.9 0.0 1.6e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CHCH PF06747.8 EGF98116.1 - 0.002 17.9 0.5 0.0035 17.2 0.3 1.3 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EGF98116.1 - 0.0039 16.9 0.1 0.0062 16.2 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like MRG PF05712.8 EGF98117.1 - 3.7e-47 159.7 0.5 4.8e-47 159.3 0.3 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EGF98117.1 - 8.9e-08 31.7 1.5 1.7e-07 30.7 1.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EGF98117.1 - 0.4 10.3 5.7 1.3 8.7 4.0 2.0 1 1 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PGP_phosphatase PF09419.5 EGF98118.1 - 1.9e-17 63.1 0.2 6.8e-14 51.5 0.2 3.2 1 1 0 1 1 1 1 Mitochondrial PGP phosphatase DUF2043 PF09740.4 EGF98118.1 - 0.022 14.8 0.6 2.6 8.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2043) WD40 PF00400.27 EGF98119.1 - 1.2e-40 135.9 9.0 4.4e-10 39.0 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Nucleoporin_C PF03177.9 EGF98122.1 - 2.7e-69 234.2 0.0 3.7e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EGF98122.1 - 7.5e-26 90.8 0.1 1.2e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like DUF2459 PF09601.5 EGF98122.1 - 0.12 12.0 0.2 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) AHSA1 PF08327.6 EGF98122.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Gag_p17 PF00540.13 EGF98122.1 - 0.18 11.5 0.0 8 6.2 0.0 2.5 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) MAT1 PF06391.8 EGF98123.1 - 0.98 8.9 4.6 1.5 8.3 3.2 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Reprolysin_5 PF13688.1 EGF98125.1 - 2.3e-45 154.9 3.5 9.6e-45 152.9 2.4 2.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EGF98125.1 - 1.4e-38 132.5 0.2 2.7e-38 131.5 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EGF98125.1 - 3.3e-32 111.9 1.2 3.3e-32 111.9 0.9 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EGF98125.1 - 3.6e-18 66.2 0.0 1e-17 64.7 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EGF98125.1 - 1.6e-13 50.6 21.1 1.6e-13 50.6 14.7 4.0 2 1 2 4 4 4 1 Disintegrin Reprolysin PF01421.14 EGF98125.1 - 3.6e-07 29.9 8.0 3.6e-07 29.9 5.5 3.0 3 1 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M43 PF05572.8 EGF98125.1 - 0.077 12.5 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Pkinase PF00069.20 EGF98127.1 - 3.8e-60 203.2 0.1 4.4e-60 203.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF98127.1 - 1.9e-19 69.7 0.0 3e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGF98127.1 - 5.3e-08 32.8 0.2 1.8e-06 27.8 0.3 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGF98127.1 - 0.022 14.3 1.3 0.025 14.1 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 EGF98127.1 - 0.025 13.6 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGF98127.1 - 0.072 12.4 0.3 0.18 11.1 0.1 1.6 1 1 1 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.4 EGF98127.1 - 0.1 11.9 0.2 13 5.0 0.0 2.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Oxysterol_BP PF01237.13 EGF98128.1 - 2.4e-103 345.3 0.0 4.4e-103 344.4 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 EGF98128.1 - 9e-19 67.3 0.2 1.8e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGF98128.1 - 0.0008 19.5 0.1 0.0028 17.8 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGF98128.1 - 0.04 14.1 0.1 0.098 12.9 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.2 EGF98128.1 - 5.7 6.8 5.5 6.8 6.6 0.3 3.5 4 1 0 4 4 4 0 Meiotic cell cortex C-terminal pleckstrin homology AAA PF00004.24 EGF98129.1 - 7.3e-29 100.6 0.0 1.2e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGF98129.1 - 9.9e-07 28.9 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGF98129.1 - 2.7e-06 27.5 0.0 6.9e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGF98129.1 - 1e-05 25.8 0.0 2.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGF98129.1 - 3.5e-05 24.6 0.0 0.0001 23.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGF98129.1 - 0.00038 20.3 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGF98129.1 - 0.00047 19.6 0.0 0.053 12.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EGF98129.1 - 0.00094 19.0 0.0 0.002 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGF98129.1 - 0.0012 18.8 0.0 0.0029 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EGF98129.1 - 0.0015 18.2 0.0 0.0072 16.0 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EGF98129.1 - 0.002 17.8 0.0 0.0054 16.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EGF98129.1 - 0.0025 17.3 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EGF98129.1 - 0.0049 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 EGF98129.1 - 0.0054 16.3 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EGF98129.1 - 0.0057 16.3 0.1 0.029 14.0 0.1 2.1 1 1 0 1 1 1 1 NACHT domain TIP49 PF06068.8 EGF98129.1 - 0.0078 14.9 0.0 0.026 13.2 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus KTI12 PF08433.5 EGF98129.1 - 0.014 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.16 EGF98129.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EGF98129.1 - 0.017 14.6 0.1 0.039 13.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain KAP_NTPase PF07693.9 EGF98129.1 - 0.018 14.0 0.3 1.9 7.4 0.1 2.4 2 1 1 3 3 3 0 KAP family P-loop domain UPF0079 PF02367.12 EGF98129.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EGF98129.1 - 0.025 13.9 0.0 0.06 12.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 EGF98129.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGF98129.1 - 0.029 13.9 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 EGF98129.1 - 0.033 13.2 0.0 0.067 12.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 EGF98129.1 - 0.04 12.7 0.0 0.068 12.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.8 EGF98129.1 - 0.043 12.7 0.1 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EGF98129.1 - 0.061 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EGF98129.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EGF98129.1 - 0.092 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EGF98129.1 - 0.096 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EGF98129.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KH_1 PF00013.24 EGF98130.1 - 2.9e-32 110.0 9.5 9.8e-10 37.9 0.1 7.4 7 0 0 7 7 7 6 KH domain KH_3 PF13014.1 EGF98130.1 - 4.1e-22 77.3 16.1 2.9e-07 29.9 0.1 7.3 8 0 0 8 8 8 5 KH domain Mem_trans PF03547.13 EGF98130.1 - 0.048 11.9 1.0 0.071 11.3 0.7 1.3 1 0 0 1 1 1 0 Membrane transport protein Macoilin PF09726.4 EGF98130.1 - 2.3 6.4 20.6 3.4 5.8 14.3 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 EGF98130.1 - 7.9 5.7 30.1 3.2 7.0 18.4 2.0 2 0 0 2 2 2 0 Vta1 like Prefoldin_2 PF01920.15 EGF98131.1 - 1.7e-10 40.5 3.3 3.8e-10 39.4 2.3 1.5 1 1 0 1 1 1 1 Prefoldin subunit DUF1319 PF07028.6 EGF98131.1 - 0.044 13.9 2.0 0.057 13.6 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) CENP-Q PF13094.1 EGF98131.1 - 0.046 13.7 3.4 0.052 13.5 2.4 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FliD_N PF02465.13 EGF98131.1 - 0.3 11.4 2.5 0.39 11.1 1.4 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus SWIRM PF04433.12 EGF98132.1 - 2.4e-34 117.3 1.1 1.9e-33 114.4 0.0 2.7 3 0 0 3 3 3 1 SWIRM domain ZZ PF00569.12 EGF98132.1 - 1.5e-06 27.6 2.1 2.6e-06 26.8 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 EGF98132.1 - 0.00015 21.7 0.1 0.00047 20.1 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGF98132.1 - 0.00019 21.4 0.1 0.00049 20.1 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Daxx PF03344.10 EGF98133.1 - 0.012 14.1 37.8 0.016 13.7 26.2 1.1 1 0 0 1 1 1 0 Daxx Family RNA_pol_Rpb4 PF03874.11 EGF98136.1 - 0.074 13.0 0.1 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb4 DUF1649 PF07855.7 EGF98139.1 - 1.5e-13 50.7 0.1 1.8e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) CCT_2 PF09425.5 EGF98139.1 - 0.031 13.8 0.1 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 Divergent CCT motif Pyridoxal_deC PF00282.14 EGF98140.1 - 5.2e-24 84.3 0.0 7.8e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGF98140.1 - 8.2e-10 37.9 0.0 1.8e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGF98140.1 - 0.0023 17.0 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2872 PF11071.3 EGF98140.1 - 0.04 13.8 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2872) Cys_Met_Meta_PP PF01053.15 EGF98140.1 - 0.15 10.3 0.0 0.39 8.9 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Reprolysin_5 PF13688.1 EGF98142.1 - 2.3e-42 145.1 2.4 2.3e-42 145.1 1.6 2.4 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EGF98142.1 - 1.4e-37 129.3 1.1 1.4e-37 129.3 0.8 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EGF98142.1 - 1e-35 123.1 0.1 1.9e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EGF98142.1 - 2.6e-18 66.7 0.0 7.6e-18 65.2 0.0 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EGF98142.1 - 1.3e-13 50.9 23.0 1.3e-13 50.9 16.0 4.1 2 1 1 3 3 3 1 Disintegrin Reprolysin PF01421.14 EGF98142.1 - 4.4e-05 23.1 3.9 0.00032 20.3 2.7 2.4 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M64 PF09471.5 EGF98142.1 - 0.0011 18.7 0.2 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 IgA Peptidase M64 Peptidase_M43 PF05572.8 EGF98142.1 - 0.0074 15.8 0.1 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A CDRN PF05174.7 EGF98143.1 - 0.058 12.8 0.0 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus HECT PF00632.20 EGF98146.1 - 1.9e-92 309.8 0.0 2.3e-92 309.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Hexokinase_2 PF03727.11 EGF98151.1 - 6.1e-77 258.1 0.3 9.1e-77 257.5 0.2 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EGF98151.1 - 2.8e-71 239.1 0.0 4.1e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Mt_ATP-synt_D PF05873.7 EGF98154.1 - 3e-10 39.9 0.4 4.3e-10 39.4 0.2 1.2 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF1327 PF07041.6 EGF98154.1 - 0.11 12.3 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) Pkinase PF00069.20 EGF98155.1 - 1.3e-52 178.5 0.0 2.4e-49 167.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGF98155.1 - 1.5e-21 76.6 0.0 3.8e-21 75.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGF98155.1 - 1.7e-08 33.7 0.0 2.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGF98155.1 - 0.00029 20.2 0.0 0.00046 19.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGF98155.1 - 0.00041 20.1 0.0 0.0008 19.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGF98155.1 - 0.078 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGF98155.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase NAM-associated PF14303.1 EGF98156.1 - 1.1e-06 29.0 0.6 1.1e-06 29.0 0.4 2.8 2 1 0 2 2 2 1 No apical meristem-associated C-terminal domain Sec20 PF03908.8 EGF98156.1 - 0.73 9.5 0.0 0.73 9.5 0.0 2.5 2 1 0 2 2 2 0 Sec20 RVP PF00077.15 EGF98158.1 - 0.074 12.9 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RNA_helicase PF00910.17 EGF98158.1 - 0.1 12.8 0.1 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA helicase DUF869 PF05911.6 EGF98158.1 - 0.36 8.9 1.6 0.39 8.8 1.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF822 PF05687.8 EGF98161.1 - 0.024 14.9 0.0 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) DHQ_synthase PF01761.15 EGF98162.1 - 1.1e-53 181.8 0.0 1.5e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EGF98162.1 - 1.7e-11 43.9 0.0 2.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase NAD_binding_4 PF07993.7 EGF98163.1 - 2.6e-38 131.3 0.0 5.9e-38 130.2 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EGF98163.1 - 1.2e-25 89.8 0.0 4.2e-24 84.7 0.0 2.5 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EGF98163.1 - 7.9e-08 32.0 0.0 2.1e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGF98163.1 - 2e-07 31.1 0.1 8.2e-07 29.1 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EGF98163.1 - 0.017 15.0 0.1 0.049 13.5 0.0 1.8 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EGF98163.1 - 0.023 14.3 0.3 0.13 11.9 0.2 2.0 1 1 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 EGF98163.1 - 0.036 14.0 0.0 3 7.8 0.0 2.5 2 0 0 2 2 2 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGF98163.1 - 0.15 10.9 0.0 0.34 9.7 0.0 1.7 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sec7 PF01369.15 EGF98164.1 - 8.5e-66 221.2 1.4 3e-65 219.4 0.0 2.5 2 1 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 EGF98164.1 - 1.1e-54 184.3 4.3 1.1e-54 184.3 3.0 2.2 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGF98164.1 - 2.3e-29 100.7 2.6 1.9e-28 97.8 0.4 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Glu_syn_central PF04898.9 EGF98167.1 - 3.7e-12 46.1 0.0 3.7e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Glutamate synthase central domain Pox_A_type_inc PF04508.7 EGF98171.1 - 0.0053 16.4 4.9 0.02 14.6 0.4 2.9 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat V_ATPase_I PF01496.14 EGF98172.1 - 2.9 5.6 3.9 3.8 5.2 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Uds1 PF15456.1 EGF98173.1 - 0.025 14.5 0.7 0.025 14.5 0.5 2.1 1 1 1 2 2 2 0 Up-regulated During Septation CcdA PF07362.7 EGF98175.1 - 0.12 12.2 0.1 0.82 9.5 0.0 2.1 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA ENTH PF01417.15 EGF98178.1 - 0.0047 16.7 0.1 0.0076 16.1 0.1 1.3 1 0 0 1 1 1 1 ENTH domain DUF3380 PF11860.3 EGF98178.1 - 0.11 12.5 0.7 0.19 11.7 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3380) Pneumo_att_G PF05539.6 EGF98178.1 - 0.2 11.0 8.5 0.27 10.5 5.9 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Pox_Ag35 PF03286.9 EGF98178.1 - 1.3 8.5 14.1 0.88 9.0 5.0 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PAH PF02671.16 EGF98179.1 - 0.091 12.3 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 Paired amphipathic helix repeat Fib_alpha PF08702.5 EGF98179.1 - 0.11 12.6 0.7 0.15 12.2 0.5 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.1 EGF98181.1 - 0.051 13.6 0.1 0.051 13.6 0.1 2.4 3 0 0 3 3 3 0 Syntaxin-like protein DUF3732 PF12532.3 EGF98185.1 - 0.016 14.6 0.3 0.044 13.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) Herpes_LMP1 PF05297.6 EGF98186.1 - 4.8 5.9 6.9 5.6 5.7 4.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DDHD PF02862.12 EGF98186.1 - 6.4 6.5 10.2 7.4 6.2 7.1 1.1 1 0 0 1 1 1 0 DDHD domain PTPlike_phytase PF14566.1 EGF98188.1 - 1.3e-100 333.6 0.0 3.3e-39 134.3 0.0 3.4 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.15 EGF98188.1 - 5.9e-06 25.8 0.0 0.28 10.7 0.0 3.8 4 0 0 4 4 4 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGF98188.1 - 0.00028 20.3 0.1 0.21 10.9 0.0 3.2 3 0 0 3 3 3 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGF98188.1 - 0.0026 18.0 0.0 2 8.6 0.0 3.7 3 0 0 3 3 3 1 Tyrosine phosphatase family CBS PF00571.23 EGF98188.1 - 0.081 12.7 0.0 0.41 10.4 0.0 2.3 2 0 0 2 2 2 0 CBS domain TFIIE-A_C-term PF11521.3 EGF98188.1 - 0.2 11.6 2.0 8.8 6.3 0.0 3.0 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha NAPRTase PF04095.11 EGF98189.1 - 2.1e-53 181.1 0.0 2.7e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family MADF_DNA_bdg PF10545.4 EGF98190.1 - 0.2 11.8 1.3 13 6.0 0.2 2.8 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Mob1_phocein PF03637.12 EGF98191.1 - 4.8e-71 238.0 0.2 5.6e-71 237.8 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family SYS1 PF09801.4 EGF98192.1 - 1.2e-23 83.7 5.3 4.2e-17 62.4 1.5 2.2 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network p450 PF00067.17 EGF98193.1 - 1e-65 222.1 0.0 1.2e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CstA PF02554.9 EGF98193.1 - 0.076 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Carbon starvation protein CstA HycI PF01750.13 EGF98194.1 - 0.036 13.6 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase maturation protease Trs65 PF12735.2 EGF98196.1 - 0.00043 19.6 12.5 0.0014 18.0 0.0 2.8 1 1 1 2 2 2 1 TRAPP trafficking subunit Trs65 Drf_GBD PF06371.8 EGF98197.1 - 6e-19 68.1 0.3 6e-19 68.1 0.2 2.9 3 1 0 3 3 3 1 Diaphanous GTPase-binding Domain GCV_T PF01571.16 EGF98199.1 - 5.5e-65 218.6 0.0 7.2e-65 218.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EGF98199.1 - 1.8e-19 69.5 0.1 3e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 EGF98199.1 - 2.2e-05 24.3 0.0 0.00071 19.4 0.0 2.2 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family TrmE_N PF10396.4 EGF98199.1 - 0.0075 16.2 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 2 GTP-binding protein TrmE N-terminus RNB PF00773.14 EGF98200.1 - 1.3e-94 317.1 0.0 1.8e-94 316.7 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EGF98200.1 - 2.7e-13 50.1 0.9 1.1e-12 48.2 0.0 2.2 2 0 0 2 2 2 1 PIN domain OB_RNB PF08206.6 EGF98200.1 - 0.00036 19.9 0.5 0.031 13.7 0.0 2.6 2 0 0 2 2 2 1 Ribonuclease B OB domain FOP_dimer PF09398.5 EGF98200.1 - 0.046 13.7 0.4 6.9 6.7 0.1 3.2 3 0 0 3 3 3 0 FOP N terminal dimerisation domain KH_1 PF00013.24 EGF98201.1 - 7.1e-06 25.5 0.2 1.5e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.18 EGF98201.1 - 0.00038 20.2 0.7 0.0007 19.4 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle KH_3 PF13014.1 EGF98201.1 - 0.0027 17.3 0.1 0.0073 15.9 0.1 1.7 1 0 0 1 1 1 1 KH domain DUF605 PF04652.11 EGF98201.1 - 0.057 12.8 23.7 0.017 14.5 10.5 2.3 2 0 0 2 2 2 0 Vta1 like Zip PF02535.17 EGF98201.1 - 1.5 7.7 8.6 2.2 7.1 6.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 EGF98201.1 - 5.8 5.0 23.5 8.6 4.4 16.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydrolase_6 PF12697.2 EGF98204.1 - 3.6e-14 53.1 0.0 5.4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGF98204.1 - 0.00019 21.1 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGF98204.1 - 0.0005 19.7 0.0 0.00061 19.4 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Med2 PF11214.3 EGF98207.1 - 0.05 13.6 0.0 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 2 DEAD PF00270.24 EGF98209.1 - 2e-33 115.2 0.1 6.6e-33 113.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGF98209.1 - 5.3e-21 74.2 0.2 2e-20 72.4 0.2 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGF98209.1 - 0.035 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF814 PF05670.8 EGF98210.1 - 9e-22 76.7 0.0 1.6e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) OPT PF03169.10 EGF98214.1 - 2.2e-52 178.3 24.2 1.5e-29 102.9 9.1 2.9 1 1 1 2 2 2 2 OPT oligopeptide transporter protein OPT PF03169.10 EGF98215.1 - 2.6e-19 69.1 3.5 2.6e-19 69.1 2.4 1.8 2 0 0 2 2 2 1 OPT oligopeptide transporter protein OPT PF03169.10 EGF98219.1 - 9.6e-126 420.7 38.6 2e-125 419.6 26.7 1.5 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Proteasome PF00227.21 EGF98220.1 - 7.3e-52 175.4 0.1 9.2e-52 175.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit GMC_oxred_N PF00732.14 EGF98221.1 - 4.8e-51 173.6 0.0 1e-50 172.5 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGF98221.1 - 2.8e-41 141.1 0.0 5.7e-41 140.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EGF98221.1 - 3.3e-05 22.9 0.0 0.024 13.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EGF98221.1 - 0.00031 19.7 0.0 0.00046 19.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EGF98221.1 - 0.00032 19.7 0.0 0.00062 18.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGF98221.1 - 0.0063 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGF98221.1 - 0.014 15.3 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain LRR_4 PF12799.2 EGF98224.1 - 0.78 9.4 4.4 26 4.5 0.1 4.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) EMP70 PF02990.11 EGF98225.1 - 1.6e-179 597.7 0.3 2.3e-179 597.2 0.2 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Rax2 PF12768.2 EGF98226.1 - 1.4e-57 195.0 14.4 2.1e-49 168.2 2.9 5.4 4 2 3 7 7 7 6 Cortical protein marker for cell polarity SH3_1 PF00018.23 EGF98226.1 - 1.3e-05 24.5 0.1 2.4e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGF98226.1 - 4.4e-05 22.9 0.2 0.00012 21.5 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGF98226.1 - 0.00022 20.6 0.2 0.00057 19.3 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain Kelch_6 PF13964.1 EGF98226.1 - 7 7.0 23.0 0.15 12.2 0.1 7.2 8 1 1 9 9 9 0 Kelch motif DUF155 PF02582.9 EGF98228.1 - 0.02 14.8 0.1 0.098 12.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 Med13_C PF06333.7 EGF98230.1 - 9e-05 21.1 0.1 9e-05 21.1 0.1 4.2 3 1 0 3 3 3 1 Mediator complex subunit 13 C-terminal DUF1262 PF06880.6 EGF98230.1 - 0.11 12.9 0.6 0.44 10.9 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1262) DUF676 PF05057.9 EGF98231.1 - 5.7e-06 25.7 0.0 9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGF98231.1 - 0.0025 17.4 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGF98231.1 - 0.0025 17.5 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_A22B PF04258.8 EGF98231.1 - 0.019 14.3 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Signal peptide peptidase Lipase_2 PF01674.13 EGF98231.1 - 0.027 13.7 0.1 0.17 11.1 0.1 2.0 1 1 0 1 1 1 0 Lipase (class 2) Abhydrolase_6 PF12697.2 EGF98231.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EGF98231.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF676 PF05057.9 EGF98232.1 - 1.2e-05 24.6 0.1 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGF98232.1 - 0.00018 21.1 0.1 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGF98232.1 - 0.00088 19.2 0.1 0.0013 18.6 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGF98232.1 - 0.0018 18.0 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family MTS PF05175.9 EGF98232.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Sugarporin_N PF11471.3 EGF98233.1 - 0.00022 20.7 3.7 0.00022 20.7 2.6 1.8 2 0 0 2 2 2 1 Maltoporin periplasmic N-terminal extension DUF2360 PF10152.4 EGF98233.1 - 0.086 13.1 0.4 0.086 13.1 0.3 1.9 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) TAP42 PF04177.7 EGF98234.1 - 2.2e-63 214.2 9.3 2.6e-63 214.0 6.5 1.0 1 0 0 1 1 1 1 TAP42-like family Adaptin_N PF01602.15 EGF98235.1 - 1.5e-140 468.9 8.4 1.8e-140 468.7 5.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EGF98235.1 - 1.3e-17 64.1 0.3 3.4e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain RIX1 PF08167.7 EGF98235.1 - 0.01 15.5 0.0 0.13 11.9 0.0 2.7 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis TIP120 PF08623.5 EGF98235.1 - 0.062 12.8 1.5 0.27 10.8 0.1 2.7 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 EGF98235.1 - 0.27 11.0 9.1 0.38 10.5 0.2 4.0 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 CENP-F_leu_zip PF10473.4 EGF98236.1 - 0.22 11.3 12.4 0.48 10.2 8.6 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2570 PF10828.3 EGF98236.1 - 3 7.5 7.5 8.5 6.0 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) VHS PF00790.14 EGF98237.1 - 5.7e-22 77.8 0.3 1.1e-21 76.9 0.2 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EGF98237.1 - 6.6e-07 29.2 0.6 0.0021 18.0 0.0 2.7 2 0 0 2 2 2 2 GAT domain DUF1539 PF07560.6 EGF98237.1 - 0.017 14.9 2.7 0.024 14.5 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) FAM70 PF14967.1 EGF98238.1 - 6.9 5.7 7.5 2.3 7.3 3.3 1.5 1 1 1 2 2 2 0 FAM70 protein Involucrin_N PF10583.4 EGF98239.1 - 0.019 15.2 0.2 0.019 15.2 0.2 2.0 2 1 0 2 2 2 0 Involucrin of squamous epithelia N-terminus Tail_P2_I PF09684.5 EGF98240.1 - 0.08 12.4 0.1 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Phage tail protein (Tail_P2_I) MIP PF00230.15 EGF98244.1 - 2.2e-29 102.5 6.5 2.7e-29 102.2 4.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3493 PF11998.3 EGF98244.1 - 0.13 12.2 3.5 0.72 9.7 2.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3493) Peptidase_M1 PF01433.15 EGF98245.1 - 8.8e-67 225.8 0.0 1.2e-66 225.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EGF98245.1 - 3.9e-41 140.0 0.5 8e-41 138.9 0.4 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EGF98245.1 - 2.3e-15 56.7 0.0 4.4e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Ribophorin_I PF04597.9 EGF98245.1 - 0.0051 15.3 0.0 0.0076 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribophorin I Peptidase_M61 PF05299.7 EGF98245.1 - 0.026 14.4 1.8 0.43 10.5 1.2 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase FTR_C PF02741.10 EGF98246.1 - 0.036 13.8 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 FTR, proximal lobe I_LWEQ PF01608.12 EGF98247.1 - 0.96 9.3 9.7 0.13 12.2 3.4 2.0 2 0 0 2 2 2 0 I/LWEQ domain Ribosomal_S18 PF01084.15 EGF98248.1 - 6.5e-14 51.5 0.1 1.1e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 CDC24 PF06395.6 EGF98249.1 - 0.033 14.2 0.5 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 CDC24 Calponin DNA_pol_viral_N PF00242.12 EGF98251.1 - 2.3 7.1 14.4 2.4 7.0 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DDHD PF02862.12 EGF98251.1 - 2.8 7.6 10.6 3.5 7.3 7.4 1.2 1 0 0 1 1 1 0 DDHD domain Apt1 PF10351.4 EGF98251.1 - 3.6 6.3 15.8 4.1 6.1 11.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3827 PF12877.2 EGF98251.1 - 4 5.4 17.8 4.8 5.1 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF874 PF05917.6 EGF98252.1 - 0.074 11.8 6.1 0.12 11.2 4.2 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Lipase_GDSL_2 PF13472.1 EGF98253.1 - 0.012 15.7 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Band_7 PF01145.20 EGF98256.1 - 0.024 14.5 1.6 0.039 13.8 1.1 1.3 1 0 0 1 1 1 0 SPFH domain / Band 7 family TetR_C_4 PF08359.6 EGF98256.1 - 0.037 13.9 0.5 0.063 13.2 0.3 1.5 1 1 0 1 1 1 0 YsiA-like protein, C-terminal region DUF817 PF05675.7 EGF98256.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF817) Dor1 PF04124.7 EGF98258.1 - 0.057 11.8 0.8 0.28 9.5 0.1 2.2 2 1 1 3 3 3 0 Dor1-like family CorA PF01544.13 EGF98258.1 - 0.17 10.8 0.5 0.5 9.3 0.1 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Profilin PF00235.14 EGF98259.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Profilin HN PF00423.14 EGF98262.1 - 0.036 12.3 1.2 0.049 11.9 0.9 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase CobT PF06213.7 EGF98263.1 - 0.76 8.8 23.3 1.2 8.2 16.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Merozoite_SPAM PF07133.6 EGF98263.1 - 7.9 6.3 41.9 14 5.5 29.1 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.7 EGF98263.1 - 8.7 5.5 29.4 14 4.8 20.4 1.3 1 0 0 1 1 1 0 SDA1 Peptidase_M16 PF00675.15 EGF98264.1 - 8.6e-06 25.5 0.1 9.1e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Phage_mat-A PF03863.8 EGF98266.1 - 0.061 12.3 0.1 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Phage maturation protein CPSF100_C PF13299.1 EGF98267.1 - 5.5e-05 23.4 0.0 9.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal DUF2973 PF11189.3 EGF98270.1 - 0.14 11.9 0.2 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) ABC_tran PF00005.22 EGF98274.1 - 1.1e-10 41.9 1.1 4e-10 40.1 0.3 2.1 1 1 1 2 2 2 1 ABC transporter SMC_N PF02463.14 EGF98274.1 - 0.00061 19.0 0.1 0.0018 17.5 0.0 1.7 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Lsm_C PF14894.1 EGF98274.1 - 0.039 13.4 0.1 0.12 11.8 0.0 1.8 1 0 0 1 1 1 0 Lsm C-terminal AAA_25 PF13481.1 EGF98274.1 - 0.051 12.9 0.2 1.1 8.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain DUF2621 PF11084.3 EGF98281.1 - 0.002 17.8 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2621) DIX PF00778.12 EGF98281.1 - 0.019 14.6 0.0 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 DIX domain AFT PF08731.6 EGF98282.1 - 0.0017 18.4 0.1 0.0017 18.4 0.1 2.0 3 0 0 3 3 3 1 Transcription factor AFT ARF7EP_C PF14949.1 EGF98282.1 - 0.99 9.8 9.0 1.2 9.5 0.3 2.9 3 0 0 3 3 3 0 ARF7 effector protein C-terminus Methyltransf_4 PF02390.12 EGF98283.1 - 0.0047 16.0 0.0 0.0072 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Glyco_transf_41 PF13844.1 EGF98284.1 - 0.0019 16.2 0.0 0.0025 15.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 41 RCC1_2 PF13540.1 EGF98285.1 - 0.0031 17.0 7.2 1.1 8.9 0.0 3.6 3 1 1 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Gp_dh_N PF00044.19 EGF98286.1 - 6.4e-60 201.5 0.1 8e-60 201.1 0.1 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 EGF98286.1 - 2.2e-24 85.7 0.0 3.4e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DUF2436 PF10365.4 EGF98286.1 - 0.011 15.3 0.2 0.02 14.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) DapB_N PF01113.15 EGF98286.1 - 0.065 13.1 0.2 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EGF98286.1 - 0.077 12.1 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Poty_coat PF00767.13 EGF98286.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Potyvirus coat protein DNA_pol_viral_N PF00242.12 EGF98287.1 - 3.8 6.4 8.4 5.3 5.9 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Glyco_hydro_16 PF00722.16 EGF98289.1 - 0.0034 16.6 0.1 0.0041 16.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 7TM_GPCR_Srt PF10321.4 EGF98291.1 - 0.01 14.6 2.6 0.013 14.2 1.8 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt IP_trans PF02121.13 EGF98291.1 - 0.031 13.4 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein GMC_oxred_N PF00732.14 EGF98292.1 - 3.5e-10 39.5 0.1 4.7e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase TFIIA_gamma_N PF02268.11 EGF98293.1 - 0.0022 17.5 0.0 0.0091 15.5 0.0 1.9 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit, helical domain Herpes_LMP1 PF05297.6 EGF98297.1 - 1.2 8.0 6.3 1.8 7.4 4.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) vMSA PF00695.14 EGF98297.1 - 1.8 7.6 8.9 2.9 7.0 6.2 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Polysacc_deac_1 PF01522.16 EGF98298.1 - 2.8e-27 94.7 0.0 1.7e-26 92.2 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGF98298.1 - 3.6e-06 26.1 0.0 9.3e-06 24.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 Rsbr_N PF08678.5 EGF98298.1 - 0.056 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Rsbr N terminal DUF727 PF05303.7 EGF98298.1 - 0.18 11.5 0.5 22 4.9 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF727) RCC1_2 PF13540.1 EGF98299.1 - 0.0057 16.2 6.4 1.1 8.9 0.0 3.4 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Tna_leader PF08053.6 EGF98299.1 - 2.7 7.4 5.4 21 4.6 0.1 2.9 3 0 0 3 3 3 0 Tryptophanese operon leader peptide ASF1_hist_chap PF04729.8 EGF98302.1 - 4.5e-62 208.2 0.7 2.4e-60 202.6 0.5 2.1 1 1 0 1 1 1 1 ASF1 like histone chaperone EF_assoc_2 PF08356.7 EGF98303.1 - 4.8e-16 58.2 0.0 7.2e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 EF hand associated V1R PF03402.9 EGF98303.1 - 0.022 14.1 2.6 3 7.1 0.4 2.4 2 1 1 3 3 3 0 Vomeronasal organ pheromone receptor family, V1R ATP-synt_8 PF00895.15 EGF98306.1 - 5.5 7.2 7.7 1.8e+02 2.4 5.3 2.5 1 1 0 1 1 1 0 ATP synthase protein 8 zf-Dof PF02701.10 EGF98307.1 - 0.019 14.8 0.1 9.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Dof domain, zinc finger CYSTM PF12734.2 EGF98307.1 - 0.031 14.3 0.1 15 5.7 0.0 2.6 3 0 0 3 3 3 0 Cysteine-rich TM module stress tolerance Sigma70_ECF PF07638.6 EGF98307.1 - 0.31 10.6 0.9 23 4.5 0.1 2.2 2 0 0 2 2 2 0 ECF sigma factor GMC_oxred_N PF00732.14 EGF98308.1 - 3.6e-10 39.4 0.1 4.9e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase SR-25 PF10500.4 EGF98313.1 - 0.006 16.0 5.6 0.0066 15.9 3.9 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BSP_II PF05432.6 EGF98313.1 - 0.011 15.0 2.4 0.012 14.9 1.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pox_Ag35 PF03286.9 EGF98313.1 - 0.017 14.6 7.5 0.019 14.5 5.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein IER PF05760.7 EGF98313.1 - 0.02 14.8 4.0 0.023 14.6 2.8 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF1388 PF07142.7 EGF98313.1 - 0.064 12.9 2.3 0.1 12.3 1.6 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) Nucleoplasmin PF03066.10 EGF98313.1 - 0.068 12.6 3.0 0.068 12.6 2.1 1.1 1 0 0 1 1 1 0 Nucleoplasmin GEMIN8 PF15348.1 EGF98313.1 - 0.29 11.1 4.8 0.35 10.8 3.3 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 NOA36 PF06524.7 EGF98313.1 - 0.3 10.2 3.6 0.31 10.2 2.5 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.1 EGF98313.1 - 0.42 10.2 8.2 0.28 10.8 4.8 1.4 1 1 0 1 1 1 0 FAM176 family DUF2413 PF10310.4 EGF98313.1 - 0.47 9.2 4.2 0.5 9.1 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Consortin_C PF15281.1 EGF98313.1 - 0.58 9.6 2.0 0.85 9.1 1.4 1.3 1 0 0 1 1 1 0 Consortin C-terminus ORC6 PF05460.8 EGF98313.1 - 1.1 8.3 10.4 1.2 8.1 7.2 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PBP1_TM PF14812.1 EGF98313.1 - 1.3 9.4 16.9 0.72 10.1 9.9 1.8 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 EGF98313.1 - 1.5 7.2 8.9 1.6 7.0 6.2 1.0 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 EGF98313.1 - 1.6 8.0 7.1 1.9 7.8 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FLO_LFY PF01698.11 EGF98313.1 - 2 7.1 5.1 2.3 6.9 3.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Adeno_terminal PF02459.10 EGF98313.1 - 2.2 6.3 4.3 2.3 6.2 3.0 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Hid1 PF12722.2 EGF98313.1 - 7.2 4.1 9.4 8.5 3.9 6.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AlkA_N PF06029.6 EGF98315.1 - 0.1 12.6 2.5 2.9 7.9 0.3 4.1 5 1 1 6 6 6 0 AlkA N-terminal domain zf-TRM13_CCCH PF11722.3 EGF98319.1 - 0.0051 16.1 0.6 20 4.6 0.0 3.1 3 0 0 3 3 3 3 CCCH zinc finger in TRM13 protein Pax7 PF12360.3 EGF98319.1 - 0.054 13.7 1.0 20 5.5 0.0 3.2 1 1 2 3 3 3 0 Paired box protein 7 Pheromone PF08015.6 EGF98319.1 - 0.064 14.0 2.8 0.21 12.4 0.0 2.7 3 0 0 3 3 3 0 Fungal mating-type pheromone YpM PF09144.5 EGF98319.1 - 0.24 11.3 2.1 0.74 9.7 0.6 1.8 1 1 1 2 2 2 0 Yersinia pseudotuberculosis mitogen Metallophos PF00149.23 EGF98320.1 - 2.8e-41 141.1 0.0 3.3e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase VWA_3 PF13768.1 EGF98320.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain PMSI1 PF15322.1 EGF98321.1 - 0.27 10.2 2.5 0.31 10.0 1.7 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Ebola_NP PF05505.7 EGF98321.1 - 1.6 6.7 8.0 1.8 6.5 5.5 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DNA_pol_viral_N PF00242.12 EGF98321.1 - 1.8 7.4 7.4 2 7.3 5.1 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Cyt-b5 PF00173.23 EGF98324.1 - 1.7e-17 62.9 0.6 4.9e-17 61.4 0.0 2.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EGF98324.1 - 9.4e-09 35.6 17.8 9.4e-09 35.6 12.3 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Citrate_synt PF00285.16 EGF98326.1 - 1.8e-17 63.1 0.0 2.2e-15 56.2 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 EGF98326.1 - 5.4e-16 58.5 0.1 1.7e-15 56.9 0.1 1.9 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 EGF98326.1 - 4.7e-11 43.0 0.0 1.3e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.1 EGF98326.1 - 1.3e-07 31.2 0.1 1.1e-05 25.0 0.0 2.7 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 EGF98326.1 - 2.9e-07 30.0 0.0 5.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain DUF2890 PF11081.3 EGF98327.1 - 2.9 7.8 11.0 3.3 7.7 5.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Pox_Ag35 PF03286.9 EGF98328.1 - 1.6 8.2 11.3 0.021 14.3 2.0 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Sdh5 PF03937.11 EGF98330.1 - 3.9e-19 68.1 0.2 5.3e-19 67.6 0.2 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase NAM-associated PF14303.1 EGF98332.1 - 2.3e-19 70.1 3.0 2.3e-19 70.1 2.1 2.0 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain MRP-S31 PF15433.1 EGF98332.1 - 1.2 8.4 10.8 1.6 8.0 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 WD40 PF00400.27 EGF98333.1 - 4.4e-52 172.1 20.4 7.2e-10 38.3 0.0 8.6 7 2 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EGF98333.1 - 7.8e-09 35.1 0.4 1.5e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGF98333.1 - 1e-08 34.6 1.4 2.2e-08 33.5 1.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EGF98333.1 - 2.1e-06 26.1 8.6 1.5 6.8 0.0 6.1 1 1 5 6 6 6 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EGF98333.1 - 0.0083 15.8 0.0 1.3 8.7 0.0 4.0 2 2 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region BAF1_ABF1 PF04684.8 EGF98333.1 - 2 7.1 20.7 4.7 5.9 14.4 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor OPT PF03169.10 EGF98335.1 - 9.8e-44 149.8 19.6 1.2e-30 106.5 7.2 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein HsbA PF12296.3 EGF98336.1 - 0.0064 16.3 0.0 0.015 15.1 0.0 1.7 1 1 0 1 1 1 1 Hydrophobic surface binding protein A DUF221 PF02714.10 EGF98337.1 - 1.8e-79 266.9 18.1 3.6e-79 265.9 12.5 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGF98337.1 - 3.2e-37 127.5 2.4 3.2e-37 127.5 1.6 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGF98337.1 - 4e-13 49.6 0.0 1e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Pkr1 PF08636.5 EGF98339.1 - 0.5 10.4 3.5 2.2 8.3 0.4 2.4 2 0 0 2 2 2 0 ER protein Pkr1 DUF1469 PF07332.6 EGF98340.1 - 0.14 11.8 0.1 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) AMP-binding PF00501.23 EGF98341.1 - 2.2e-70 237.1 0.0 3.2e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EGF98341.1 - 5.2e-66 222.0 0.0 8.3e-66 221.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EGF98341.1 - 6.7e-11 42.3 0.0 4.2e-10 39.7 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 EGF98341.1 - 3.2e-10 39.8 0.0 5.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EGF98341.1 - 5.5e-08 33.6 0.0 1.7e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EGF98341.1 - 0.00059 18.6 0.0 0.0023 16.6 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_deac_1 PF01522.16 EGF98342.1 - 7.8e-22 77.2 0.0 1.4e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Mucin PF01456.12 EGF98342.1 - 0.078 12.7 8.0 0.16 11.7 5.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein GARS_C PF02843.11 EGF98343.1 - 0.07 13.3 0.3 0.096 12.8 0.2 1.1 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain Pkinase PF00069.20 EGF98344.1 - 4.1e-36 124.4 0.0 9.6e-25 87.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGF98344.1 - 3.6e-24 85.2 0.0 5.5e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGF98344.1 - 0.0032 16.4 0.0 0.006 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pyr_redox_2 PF07992.9 EGF98345.1 - 1.2e-09 38.3 0.1 1.3e-06 28.4 0.1 3.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGF98345.1 - 5e-08 33.2 0.1 9.5e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGF98345.1 - 0.00021 20.3 1.1 0.0076 15.2 0.1 2.5 2 1 2 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) Plus-3 PF03126.13 EGF98345.1 - 0.0046 16.9 0.0 5 7.2 0.0 2.6 2 0 0 2 2 2 2 Plus-3 domain SUI1 PF01253.17 EGF98345.1 - 0.058 13.2 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor SUI1 DUF1690 PF07956.6 EGF98347.1 - 1.1e-08 35.1 0.1 1.3e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) CHCH PF06747.8 EGF98347.1 - 0.0088 15.9 0.2 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 CHCH domain FCH PF00611.18 EGF98347.1 - 0.064 13.4 0.2 0.13 12.5 0.0 1.6 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain RE_Eco47II PF09553.5 EGF98347.1 - 0.065 12.3 0.0 0.074 12.1 0.0 1.0 1 0 0 1 1 1 0 Eco47II restriction endonuclease Zn_clus PF00172.13 EGF98348.1 - 3.2e-05 23.7 2.8 4.4e-05 23.2 2.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.4 EGF98348.1 - 0.075 11.6 0.0 0.097 11.3 0.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein KIF1B PF12423.3 EGF98348.1 - 0.14 12.2 0.4 0.35 10.9 0.3 1.6 1 0 0 1 1 1 0 Kinesin protein 1B Plant_tran PF04827.9 EGF98349.1 - 1.4e-37 129.1 0.0 1.7e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.1 EGF98349.1 - 1.3e-07 31.3 0.0 2.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease MBOAT_2 PF13813.1 EGF98351.1 - 1.9e-16 59.8 0.2 6.6e-16 58.1 0.1 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SPC12 PF06645.8 EGF98351.1 - 0.075 12.8 0.2 0.21 11.4 0.2 1.8 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Dna2 PF08696.6 EGF98352.1 - 4.2e-39 134.0 0.5 9.6e-39 132.8 0.0 1.9 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 EGF98352.1 - 2.2e-35 121.8 0.0 4.4e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arrestin_N PF00339.24 EGF98356.1 - 0.016 15.0 0.1 0.18 11.5 0.0 2.4 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Mg296 PF09644.5 EGF98357.1 - 0.038 13.8 0.2 0.15 11.9 0.1 1.9 1 0 0 1 1 1 0 Mg296 protein ATP_synt_H PF05493.8 EGF98359.1 - 2.5e-23 81.9 0.4 2.8e-23 81.7 0.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit H ARL6IP6 PF15062.1 EGF98359.1 - 0.00032 20.5 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Haemopoietic lineage transmembrane helix YbjM PF11045.3 EGF98359.1 - 0.06 13.1 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae Claudin_2 PF13903.1 EGF98359.1 - 0.081 12.6 0.2 0.081 12.6 0.2 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4131 PF13567.1 EGF98359.1 - 0.1 12.0 0.5 0.12 11.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RecT PF03837.9 EGF98361.1 - 0.054 12.7 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 RecT family B PF02216.11 EGF98361.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 B domain CENP-B_dimeris PF09026.5 EGF98362.1 - 0.061 13.5 0.5 0.072 13.3 0.3 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pex19 PF04614.7 EGF98362.1 - 0.096 12.2 0.6 0.12 11.9 0.4 1.1 1 0 0 1 1 1 0 Pex19 protein family UBN2_2 PF14227.1 EGF98363.1 - 0.0012 18.4 1.2 0.0012 18.4 0.8 2.4 2 1 1 3 3 3 2 gag-polypeptide of LTR copia-type CPSase_L_D2 PF02786.12 EGF98365.1 - 2.6e-78 262.1 0.5 4.4e-78 261.4 0.3 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EGF98365.1 - 3.7e-69 232.0 0.0 7e-69 231.1 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EGF98365.1 - 7.9e-37 125.7 0.2 2.3e-36 124.2 0.0 2.0 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGF98365.1 - 5.8e-30 103.4 0.0 1.5e-29 102.0 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EGF98365.1 - 5.6e-28 98.1 0.0 1.4e-27 96.9 0.0 1.7 2 0 0 2 2 1 1 HMGL-like ATP-grasp_4 PF13535.1 EGF98365.1 - 1.1e-19 70.8 0.3 2.1e-19 69.9 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGF98365.1 - 4.6e-17 61.7 0.1 3.7e-16 58.7 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EGF98365.1 - 1.2e-16 60.0 3.7 4.9e-16 58.1 2.4 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EGF98365.1 - 1.6e-12 47.2 0.0 2.9e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EGF98365.1 - 1e-10 41.1 3.4 2.7e-05 23.7 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 EGF98365.1 - 9.4e-07 28.3 0.1 2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGF98365.1 - 2.4e-05 24.2 0.0 5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EGF98365.1 - 4.3e-05 23.7 0.3 0.51 10.6 0.0 3.0 2 0 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 EGF98365.1 - 0.0011 18.3 1.0 0.053 12.8 0.0 2.4 2 0 0 2 2 2 1 HlyD family secretion protein NQRA PF05896.6 EGF98365.1 - 0.0012 18.1 0.2 0.0023 17.1 0.1 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RimK PF08443.6 EGF98365.1 - 0.0012 18.3 0.0 0.0039 16.6 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EGF98365.1 - 0.0014 18.2 0.1 0.0034 16.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.14 EGF98365.1 - 0.018 14.7 0.6 0.072 12.7 0.2 2.1 1 1 1 2 2 2 0 Glycine cleavage H-protein HlyD_2 PF12700.2 EGF98365.1 - 0.22 10.6 0.1 5.4 6.0 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein LRR_8 PF13855.1 EGF98366.1 - 0.41 10.4 3.4 1.5 8.6 0.0 3.4 4 0 0 4 4 4 0 Leucine rich repeat AA_permease PF00324.16 EGF98367.1 - 3e-140 467.7 42.9 3.4e-140 467.5 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGF98367.1 - 1.2e-33 116.3 49.6 1.9e-33 115.6 34.4 1.3 1 1 0 1 1 1 1 Amino acid permease TGF_beta_GS PF08515.7 EGF98368.1 - 0.022 14.1 1.6 0.022 14.1 1.1 2.0 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Zn_clus PF00172.13 EGF98370.1 - 3.2e-05 23.7 2.8 4.4e-05 23.2 2.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.4 EGF98370.1 - 0.075 11.6 0.0 0.096 11.3 0.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein KIF1B PF12423.3 EGF98370.1 - 0.14 12.2 0.4 0.35 10.9 0.3 1.7 1 0 0 1 1 1 0 Kinesin protein 1B PaREP1 PF05942.6 EGF98372.1 - 0.061 13.1 1.1 1.1 9.1 0.2 2.1 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family Pepsin-I3 PF06394.8 EGF98372.1 - 0.13 11.9 0.3 0.48 10.1 0.0 2.0 2 1 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain PIG-S PF10510.4 EGF98376.1 - 1.8e-09 36.8 0.1 2e-09 36.6 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein START PF01852.14 EGF98377.1 - 6.1e-07 28.9 0.0 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 START domain PCNA_N PF00705.13 EGF98378.1 - 0.011 15.2 0.4 0.18 11.3 0.1 2.4 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain Abhydrolase_6 PF12697.2 EGF98379.1 - 3.7e-09 36.8 0.0 7.5e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGF98379.1 - 0.0028 17.4 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGF98379.1 - 0.058 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_M3 PF01432.15 EGF98380.1 - 6.9e-127 424.2 0.5 9e-127 423.8 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EGF98380.1 - 0.054 12.8 0.2 0.093 12.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like GRAB PF10375.4 EGF98381.1 - 3.2e-06 26.5 0.1 1.3e-05 24.5 0.1 2.1 1 0 0 1 1 1 1 GRIP-related Arf-binding domain HALZ PF02183.13 EGF98381.1 - 0.11 12.2 0.2 0.11 12.2 0.2 5.1 5 1 0 5 5 5 0 Homeobox associated leucine zipper DUF3584 PF12128.3 EGF98381.1 - 8 3.6 42.4 1.9 5.7 24.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Acyltransferase PF01553.16 EGF98384.1 - 0.0026 17.2 0.0 0.0066 15.8 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase DEAD PF00270.24 EGF98385.1 - 3.2e-44 150.4 0.0 3.5e-43 147.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGF98385.1 - 3.9e-25 87.5 0.0 1.2e-24 85.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGF98385.1 - 0.00095 18.0 0.0 0.0017 17.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 EGF98385.1 - 0.017 14.4 0.0 0.056 12.7 0.0 1.9 1 1 0 1 1 1 0 SecA DEAD-like domain HTH_IclR PF09339.5 EGF98386.1 - 0.063 12.8 0.2 8.7 6.0 0.0 3.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain Arf PF00025.16 EGF98387.1 - 1.4e-57 193.7 0.0 1.5e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGF98387.1 - 1.5e-11 43.9 0.0 1.8e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EGF98387.1 - 2.2e-09 36.7 0.0 2.7e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGF98387.1 - 2.7e-09 36.2 0.1 4.2e-06 25.6 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EGF98387.1 - 3e-08 33.6 0.0 3.6e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGF98387.1 - 7.6e-08 32.8 0.0 9.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EGF98387.1 - 4.2e-06 26.0 0.0 4.8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EGF98387.1 - 0.0026 17.0 0.1 0.0075 15.5 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MT-A70 PF05063.9 EGF98390.1 - 0.16 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 MT-A70 Laminin_II PF06009.7 EGF98391.1 - 0.031 14.0 3.4 2.2 8.0 0.4 2.3 1 1 1 2 2 2 0 Laminin Domain II HemX PF04375.9 EGF98391.1 - 0.032 12.8 1.7 0.05 12.1 1.2 1.2 1 0 0 1 1 1 0 HemX Rootletin PF15035.1 EGF98391.1 - 0.034 14.1 10.2 0.051 13.5 7.0 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.3 EGF98391.1 - 0.18 11.6 6.2 0.15 11.9 2.9 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EGF98391.1 - 0.28 10.9 7.9 0.65 9.7 5.5 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EGF98391.1 - 0.3 10.9 1.7 0.46 10.3 0.1 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EGF98391.1 - 0.65 10.4 5.7 0.91 9.9 1.0 2.9 2 1 1 3 3 3 0 SlyX IncA PF04156.9 EGF98391.1 - 9.3 5.8 12.5 9.7 5.7 5.1 2.1 1 1 1 2 2 2 0 IncA protein PsaN PF05479.6 EGF98392.1 - 0.047 13.6 0.4 0.31 11.0 0.1 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) DASH_Hsk3 PF08227.6 EGF98392.1 - 0.16 12.1 0.8 0.35 11.1 0.5 1.5 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like DUF669 PF05037.8 EGF98393.1 - 0.078 12.8 0.0 0.55 10.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF669) DUF3829 PF12889.2 EGF98395.1 - 0.027 13.6 0.6 0.046 12.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) Clat_adaptor_s PF01217.15 EGF98397.1 - 3.5e-19 68.9 0.2 2.8e-16 59.5 0.3 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.1 EGF98397.1 - 0.047 13.6 0.3 0.073 13.0 0.2 1.3 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF4494 PF14902.1 EGF98398.1 - 0.052 13.1 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4494) WEMBL PF05701.6 EGF98399.1 - 0.12 10.8 0.5 0.16 10.3 0.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light MOZART1 PF12554.3 EGF98400.1 - 2.1e-18 65.4 0.1 2.6e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Glyoxal_oxid_N PF07250.6 EGF98402.1 - 8e-45 152.7 0.0 6.6e-43 146.5 0.0 2.5 3 0 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EGF98402.1 - 3.2e-19 68.8 0.0 6.6e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EGF98402.1 - 0.026 14.2 7.6 0.2 11.4 0.0 3.9 4 1 0 4 4 4 0 Galactose oxidase, central domain Aa_trans PF01490.13 EGF98403.1 - 1.3e-65 221.5 31.6 1.5e-65 221.3 21.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EGF98403.1 - 0.0004 19.3 16.8 0.0004 19.3 11.6 2.3 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Pkinase PF00069.20 EGF98407.1 - 6.9e-53 179.4 0.0 8.8e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF98407.1 - 4.6e-35 120.9 0.0 5.7e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGF98407.1 - 3.8e-07 29.3 0.0 1.7e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGF98407.1 - 0.00046 19.3 0.0 0.00089 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGF98407.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EGF98407.1 - 0.1 11.9 0.2 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family DUF3591 PF12157.3 EGF98411.1 - 3.2e-171 569.7 2.1 4.4e-171 569.3 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EGF98411.1 - 0.0011 18.5 4.9 0.0028 17.2 3.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGF98411.1 - 0.21 11.5 2.2 0.35 10.8 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle PIN_3 PF13470.1 EGF98412.1 - 0.11 13.1 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 PIN domain Ribosomal_L7Ae PF01248.21 EGF98413.1 - 1e-21 76.2 0.5 1.8e-21 75.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EGF98413.1 - 0.017 14.9 0.1 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 Lipase_GDSL PF00657.17 EGF98415.1 - 4.8e-11 42.9 0.2 6.6e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aminotran_1_2 PF00155.16 EGF98418.1 - 2e-36 125.7 0.0 2.6e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGF98418.1 - 5.4e-05 22.4 0.0 8.5e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EGF98418.1 - 0.0084 14.4 0.0 0.014 13.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.16 EGF98418.1 - 0.026 13.4 0.0 0.053 12.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III Rotamase PF00639.16 EGF98418.1 - 0.16 12.7 0.4 2.4 8.9 0.3 2.4 1 1 1 2 2 2 0 PPIC-type PPIASE domain MCM PF00493.18 EGF98419.1 - 3.8e-122 407.2 1.5 3.9e-121 403.9 1.0 2.1 1 1 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EGF98419.1 - 4.3e-22 78.7 22.1 4.3e-22 78.7 15.3 1.9 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EGF98419.1 - 9.8e-16 58.3 0.1 4.6e-15 56.1 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGF98419.1 - 5.3e-07 29.0 0.0 1.4e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGF98419.1 - 0.00019 21.0 0.0 0.078 12.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) zinc_ribbon_2 PF13240.1 EGF98419.1 - 0.55 9.7 3.0 3.8 7.1 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Ham1p_like PF01725.11 EGF98421.1 - 0.014 14.7 0.0 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Ham1 family DUF2031 PF09592.5 EGF98421.1 - 1.9 7.5 6.2 3.3 6.7 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) WBS_methylT PF12589.3 EGF98422.1 - 1.2e-16 60.8 10.0 2e-16 60.2 7.0 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EGF98422.1 - 4.4e-09 36.7 0.0 8.4e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGF98422.1 - 8.5e-06 26.0 0.0 4.8e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGF98422.1 - 3.2e-05 23.5 0.2 5.3e-05 22.8 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGF98422.1 - 4e-05 24.0 0.1 0.00012 22.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGF98422.1 - 5.6e-05 22.9 0.0 7.1e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGF98422.1 - 0.00021 21.8 0.1 0.0003 21.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EGF98422.1 - 0.0012 18.9 0.0 0.0038 17.3 0.0 1.8 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase Methyltransf_26 PF13659.1 EGF98422.1 - 0.037 14.0 0.0 0.079 12.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.13 EGF98422.1 - 0.055 12.9 2.2 0.32 10.4 0.0 2.1 2 0 0 2 2 2 0 DNA methylase Methyltransf_32 PF13679.1 EGF98422.1 - 0.083 12.5 0.4 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF4419 PF14388.1 EGF98426.1 - 0.02 14.1 0.2 0.058 12.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4419) Catalase PF00199.14 EGF98428.1 - 2.2e-159 530.2 3.8 2.6e-159 530.0 2.7 1.1 1 0 0 1 1 1 1 Catalase zf-MYND PF01753.13 EGF98429.1 - 7.8e-10 38.4 8.0 7.8e-10 38.4 5.5 2.1 2 1 0 2 2 2 1 MYND finger Herpes_UL25 PF01499.11 EGF98431.1 - 0.0036 15.6 0.1 0.0079 14.5 0.0 1.5 2 0 0 2 2 2 1 Herpesvirus UL25 family Methyltransf_16 PF10294.4 EGF98431.1 - 0.0094 15.4 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGF98431.1 - 0.049 14.2 0.0 0.15 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGF98431.1 - 0.43 11.0 2.9 1.2 9.6 0.0 3.0 3 1 0 3 3 3 0 Methyltransferase domain Rad60-SLD PF11976.3 EGF98432.1 - 7.4e-22 76.8 0.7 1.3e-21 76.0 0.3 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGF98432.1 - 2.5e-09 36.4 0.1 3.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family PPO1_KFDV PF12143.3 EGF98432.1 - 0.19 11.6 0.8 0.39 10.6 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF_B2219) Rad60-SLD PF11976.3 EGF98433.1 - 1.3e-11 43.9 0.0 1.7e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGF98433.1 - 0.089 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin family Alpha_kinase PF02816.13 EGF98435.1 - 8.5e-06 25.5 0.2 1.1e-05 25.2 0.2 1.2 1 0 0 1 1 1 1 Alpha-kinase family Rad60-SLD PF11976.3 EGF98437.1 - 1.9e-07 30.6 0.3 5.9e-07 29.0 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Mmp37 PF09139.6 EGF98438.1 - 0.11 11.4 3.3 0.14 11.1 2.3 1.2 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 PNK3P PF08645.6 EGF98438.1 - 0.16 11.3 0.6 0.21 10.9 0.4 1.3 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase DUF2992 PF11208.3 EGF98438.1 - 6.5 6.6 7.3 7 6.5 4.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2992) Adipogenin PF15202.1 EGF98439.1 - 0.023 14.5 1.1 0.036 13.9 0.8 1.2 1 0 0 1 1 1 0 Adipogenin VitK2_biosynth PF02621.9 EGF98440.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Menaquinone biosynthesis DUF1528 PF07515.6 EGF98441.1 - 0.2 11.6 1.5 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) HlyD PF00529.15 EGF98442.1 - 0.54 9.5 11.7 0.69 9.1 8.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Nop25 PF09805.4 EGF98442.1 - 0.78 9.8 26.8 1.8 8.6 4.8 2.2 1 1 1 2 2 2 0 Nucleolar protein 12 (25kDa) Selenoprotein_S PF06936.6 EGF98442.1 - 0.85 9.1 9.9 1.2 8.6 6.9 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF1517 PF07466.6 EGF98442.1 - 1.4 7.8 8.0 4.9 6.0 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1517) U79_P34 PF03064.11 EGF98442.1 - 2.3 7.6 8.0 2.9 7.3 5.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4554 PF15091.1 EGF98442.1 - 4.2 6.0 5.2 5.4 5.6 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) IncA PF04156.9 EGF98442.1 - 4.3 6.8 9.8 5.2 6.6 6.8 1.1 1 0 0 1 1 1 0 IncA protein Metal_resist PF13801.1 EGF98442.1 - 4.4 7.3 14.8 4.6 7.2 9.1 1.7 1 1 1 2 2 2 0 Heavy-metal resistance ATP-gua_PtransN PF02807.10 EGF98444.1 - 7.3e-05 22.8 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain FliW PF02623.10 EGF98444.1 - 0.069 12.7 0.0 4 7.0 0.0 2.2 2 0 0 2 2 2 0 FliW protein SPX PF03105.14 EGF98445.1 - 6.6e-25 88.4 6.2 2.6e-23 83.2 4.3 2.0 1 1 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EGF98445.1 - 2.3e-10 40.1 11.5 4.9e-10 39.1 8.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGF98445.1 - 2.1e-08 34.0 10.6 4.2e-08 33.0 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGF98445.1 - 3e-08 33.3 8.7 3e-08 33.3 6.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGF98445.1 - 5.1e-08 32.4 9.2 1e-07 31.4 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGF98445.1 - 4.8e-07 29.3 3.8 4.8e-07 29.3 2.6 3.0 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.1 EGF98445.1 - 8.3e-07 28.6 9.4 2.2e-06 27.2 6.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGF98445.1 - 1e-06 28.2 12.3 1.8e-06 27.5 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGF98445.1 - 0.00027 20.4 9.7 0.0018 17.8 4.8 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain PolC_DP2 PF03833.8 EGF98445.1 - 0.00048 17.9 0.2 0.00056 17.7 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zf-Apc11 PF12861.2 EGF98445.1 - 0.093 12.5 7.7 0.16 11.7 4.0 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGF98445.1 - 0.2 11.7 8.8 0.3 11.2 4.8 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger HEAT_2 PF13646.1 EGF98446.1 - 0.00014 22.0 2.1 0.061 13.6 0.0 5.1 5 2 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 EGF98446.1 - 0.00021 21.7 0.1 0.77 10.3 0.0 4.9 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.17 EGF98446.1 - 0.0013 18.6 2.9 26 5.2 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.2 EGF98446.1 - 1.5 8.6 8.9 1.6 8.5 0.0 4.1 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF421 PF04239.7 EGF98447.1 - 0.016 14.7 1.1 0.047 13.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF421) zf-C2H2_jaz PF12171.3 EGF98448.1 - 0.12 12.4 1.1 0.12 12.4 0.8 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Orthopox_F14 PF06076.7 EGF98448.1 - 0.19 11.7 1.1 0.27 11.3 0.7 1.2 1 0 0 1 1 1 0 Orthopoxvirus F14 protein DUF4130 PF13566.1 EGF98449.1 - 0.022 14.3 0.3 0.046 13.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 GIY-YIG PF01541.19 EGF98452.1 - 1e-07 32.1 0.0 1.9e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-RING-like PF08746.6 EGF98452.1 - 0.023 14.6 0.2 0.023 14.6 0.1 2.1 2 0 0 2 2 2 0 RING-like domain FANCL_C PF11793.3 EGF98452.1 - 0.22 11.5 1.5 1.1 9.3 0.1 2.5 3 0 0 3 3 3 0 FANCL C-terminal domain Herpes_Helicase PF02689.9 EGF98455.1 - 1e-08 33.4 0.1 1.1e-08 33.3 0.1 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EGF98455.1 - 0.0021 18.1 0.1 0.0041 17.2 0.0 1.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EGF98455.1 - 0.028 13.9 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TRM PF02005.11 EGF98457.1 - 1e-117 393.2 0.0 1.4e-117 392.8 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.1 EGF98457.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EGF98457.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein RhoGAP PF00620.22 EGF98458.1 - 1.3e-12 47.6 0.1 1e-11 44.6 0.0 2.0 1 1 0 2 2 2 1 RhoGAP domain HNOB PF07700.10 EGF98458.1 - 0.11 12.0 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Heme NO binding G3P_antiterm PF04309.7 EGF98459.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator SNF2_N PF00176.18 EGF98460.1 - 2.2e-11 43.1 0.1 3e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGF98464.1 - 1.4e-43 148.2 0.0 3.8e-42 143.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGF98464.1 - 8.5e-28 96.0 0.0 1.3e-26 92.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGF98464.1 - 0.00093 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EGF98464.1 - 0.017 14.2 0.0 0.035 13.1 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit CS PF04969.11 EGF98465.1 - 7.7e-19 68.0 2.4 8.6e-19 67.8 0.9 1.6 2 0 0 2 2 2 1 CS domain DUF4404 PF14357.1 EGF98465.1 - 2.9 8.3 5.4 0.75 10.2 0.7 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Ribosomal_S11 PF00411.14 EGF98466.1 - 0.00013 22.1 3.5 0.28 11.3 0.1 2.9 3 0 0 3 3 3 2 Ribosomal protein S11 Peptidase_A2E PF12382.3 EGF98466.1 - 0.066 13.0 0.0 0.22 11.2 0.0 1.8 1 1 1 2 2 2 0 Retrotransposon peptidase Phasin PF05597.6 EGF98467.1 - 0.57 9.9 3.3 2.8 7.7 0.3 2.2 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF648 PF04890.8 EGF98467.1 - 1.6 7.8 6.5 0.68 9.0 2.0 1.8 1 1 0 2 2 2 0 Family of unknown function (DUF648) Alb1 PF09135.6 EGF98467.1 - 2.1 8.9 6.4 1.2 9.7 1.0 2.2 2 0 0 2 2 2 0 Alb1 VLPT PF07122.6 EGF98469.1 - 0.16 11.6 1.8 0.32 10.6 1.2 1.5 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) SNF2_N PF00176.18 EGF98470.1 - 4.2e-44 150.5 0.6 4.7e-44 150.3 0.4 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGF98470.1 - 1.5e-07 31.0 0.0 1.8e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGF98470.1 - 0.0042 16.9 0.0 0.0071 16.1 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGF98471.1 - 2.2e-13 49.8 0.0 4.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SWIB PF02201.13 EGF98474.1 - 5.5e-18 64.4 0.1 1.2e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Tektin PF03148.9 EGF98474.1 - 0.048 12.1 0.6 0.063 11.8 0.4 1.1 1 0 0 1 1 1 0 Tektin family bZIP_1 PF00170.16 EGF98475.1 - 2.7e-07 30.4 11.4 2.7e-07 30.4 7.9 2.1 2 0 0 2 2 2 1 bZIP transcription factor CENP-Q PF13094.1 EGF98475.1 - 4.9e-05 23.4 5.7 9.2e-05 22.5 3.9 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_2 PF07716.10 EGF98475.1 - 0.00055 19.6 10.4 0.00055 19.6 7.2 2.0 2 0 0 2 2 2 1 Basic region leucine zipper Taxilin PF09728.4 EGF98475.1 - 0.0018 17.4 6.9 0.0026 16.8 4.8 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein HAP1_N PF04849.8 EGF98475.1 - 0.0019 17.2 0.6 0.0022 16.9 0.4 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region TSC22 PF01166.13 EGF98475.1 - 0.094 12.6 3.3 0.22 11.4 2.3 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family AnfO_nitrog PF09582.5 EGF98475.1 - 0.11 11.6 0.2 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DUF904 PF06005.7 EGF98475.1 - 2.9 8.2 10.8 0.55 10.5 4.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) LRR_4 PF12799.2 EGF98476.1 - 0.55 9.9 7.4 0.92 9.2 0.5 3.9 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) SET PF00856.23 EGF98483.1 - 3.4e-05 24.2 0.0 4.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 SET domain Voltage_CLC PF00654.15 EGF98484.1 - 0.0079 15.2 0.8 0.01 14.8 0.5 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel zf-C2H2 PF00096.21 EGF98484.1 - 0.24 11.7 2.7 3.5 8.1 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGF98484.1 - 0.32 11.4 6.3 0.81 10.1 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Dynamin_M PF01031.15 EGF98485.1 - 5.1e-102 340.6 0.0 7.8e-102 340.0 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EGF98485.1 - 4.8e-54 182.6 0.0 8.6e-54 181.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EGF98485.1 - 1e-27 95.8 2.6 1e-27 95.8 1.8 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGF98485.1 - 0.00099 19.0 0.0 0.0096 15.8 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGF98485.1 - 0.019 15.4 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DUF1870 PF08965.5 EGF98485.1 - 0.062 12.9 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) PTPA PF03095.10 EGF98486.1 - 1.2e-89 300.4 0.4 1.4e-89 300.2 0.3 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Spin-Ssty PF02513.12 EGF98486.1 - 0.0017 17.8 1.9 0.0046 16.4 1.3 1.7 1 0 0 1 1 1 1 Spin/Ssty Family YqaJ PF09588.5 EGF98486.1 - 0.14 12.1 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain AAA PF00004.24 EGF98487.1 - 5e-41 139.9 0.0 1e-40 138.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EGF98487.1 - 7.2e-06 26.0 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGF98487.1 - 8.2e-06 25.9 0.0 0.00069 19.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGF98487.1 - 1.3e-05 24.9 0.1 7.3e-05 22.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EGF98487.1 - 0.00052 19.0 0.0 0.00096 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EGF98487.1 - 0.00061 19.8 0.0 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGF98487.1 - 0.0034 17.0 0.2 0.0093 15.7 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EGF98487.1 - 0.0034 16.4 0.0 0.0079 15.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGF98487.1 - 0.0043 17.8 0.1 0.0095 16.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGF98487.1 - 0.009 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGF98487.1 - 0.012 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGF98487.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGF98487.1 - 0.025 14.7 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EGF98487.1 - 0.026 14.5 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EGF98487.1 - 0.031 13.3 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 EGF98487.1 - 0.039 13.5 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EGF98487.1 - 0.044 13.1 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EGF98487.1 - 0.046 14.0 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EGF98487.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EGF98487.1 - 0.098 12.1 0.0 0.31 10.4 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGF98487.1 - 0.099 11.7 0.8 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI UBN2_2 PF14227.1 EGF98488.1 - 4.7e-09 35.8 0.2 8.1e-09 35.0 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGF98488.1 - 8.6e-07 28.7 0.2 1.6e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EGF98488.1 - 0.00021 20.6 0.0 0.00047 19.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) DUF1759 PF03564.10 EGF98488.1 - 0.036 13.8 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF987 PF06174.6 EGF98488.1 - 0.056 12.9 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF987) TAP42 PF04177.7 EGF98493.1 - 2.1e-63 214.3 9.2 2.5e-63 214.1 6.4 1.1 1 0 0 1 1 1 1 TAP42-like family Adaptin_N PF01602.15 EGF98494.1 - 5e-78 262.6 2.4 3.8e-57 193.8 0.7 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EGF98494.1 - 7.8e-18 64.8 0.4 2.2e-17 63.4 0.0 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain RIX1 PF08167.7 EGF98494.1 - 0.05 13.2 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis MTP18 PF10558.4 EGF98495.1 - 0.081 12.7 0.2 2.1 8.1 0.0 2.5 2 1 1 3 3 3 0 Mitochondrial 18 KDa protein (MTP18) tRNA-synt_1e PF01406.14 EGF98497.1 - 1.9e-123 411.4 0.3 1.9e-123 411.4 0.2 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EGF98497.1 - 1.8e-06 26.9 5.3 0.00036 19.3 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGF98497.1 - 5.8e-05 21.3 0.0 0.0017 16.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.16 EGF98497.1 - 0.0049 15.5 2.8 0.0064 15.1 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain Dna2 PF08696.6 EGF98497.1 - 0.041 13.1 0.0 0.041 13.1 0.0 2.9 3 1 0 3 3 3 0 DNA replication factor Dna2 UBN2_2 PF14227.1 EGF98498.1 - 1.4e-05 24.6 0.2 3.1e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EGF98498.1 - 2.8e-05 23.4 0.0 6.5e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 EGF98498.1 - 3.5e-05 23.5 0.0 7.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGF98500.1 - 9.9e-07 28.3 0.5 1.9e-06 27.4 0.4 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGF98500.1 - 7.7e-05 22.4 0.4 7.7e-05 22.4 0.3 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EGF98500.1 - 9.1e-05 21.7 0.0 0.00021 20.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) DUF1759 PF03564.10 EGF98500.1 - 0.065 13.0 0.5 0.13 12.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) FRG1 PF06229.7 EGF98503.1 - 3.7e-16 59.1 1.0 1.8e-14 53.6 0.7 2.5 1 1 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EGF98503.1 - 0.0017 18.4 0.0 0.044 13.8 0.0 2.4 2 0 0 2 2 2 1 Fascin domain DUF1754 PF08555.5 EGF98503.1 - 5.6 7.6 12.1 1.3 9.6 4.6 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PXT1 PF15214.1 EGF98504.1 - 1.4e-06 28.4 4.3 3.3 8.0 0.1 4.5 4 0 0 4 4 4 4 Peroxisomal testis-specific protein 1 DHquinase_II PF01220.14 EGF98504.1 - 0.0019 17.5 0.1 16 4.8 0.0 3.5 3 0 0 3 3 3 2 Dehydroquinase class II Phospholip_A2_3 PF09056.6 EGF98504.1 - 0.33 11.1 0.4 1.2 9.3 0.0 2.1 4 0 0 4 4 4 0 Prokaryotic phospholipase A2 Rota_NS26 PF01525.11 EGF98504.1 - 0.45 10.2 2.2 28 4.3 0.1 2.9 3 0 0 3 3 3 0 Rotavirus NS26 AvrE PF11725.3 EGF98504.1 - 0.58 7.1 0.3 9.4 3.1 0.0 2.5 3 0 0 3 3 3 0 Pathogenicity factor UQ_con PF00179.21 EGF98505.1 - 0.0015 18.0 0.3 1.4 8.3 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme CRT10 PF08728.5 EGF98507.1 - 0.69 7.8 4.1 1 7.2 2.8 1.1 1 0 0 1 1 1 0 CRT10 Med19 PF10278.4 EGF98507.1 - 3.3 7.3 7.1 44 3.7 4.4 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Helicase_C PF00271.26 EGF98510.1 - 0.0058 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DnaJ PF00226.26 EGF98512.1 - 6.4e-19 67.4 0.6 1.5e-18 66.2 0.0 2.0 2 1 0 2 2 2 1 DnaJ domain Helicase_C PF00271.26 EGF98516.1 - 2.1e-11 43.4 0.0 3.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ligase_CoA PF00549.14 EGF98516.1 - 0.13 11.8 0.2 0.49 9.9 0.1 1.8 1 1 0 1 1 1 0 CoA-ligase Glyco_hydro_12 PF01670.11 EGF98517.1 - 1e-15 57.8 0.0 1.9e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 UCR_UQCRX_QCR9 PF05365.7 EGF98518.1 - 4.6e-27 93.4 1.2 5e-27 93.2 0.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like MIP PF00230.15 EGF98519.1 - 3.8e-06 26.5 1.5 4.7e-06 26.2 1.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein NfeD PF01957.13 EGF98520.1 - 0.041 14.0 0.3 0.041 14.0 0.2 2.2 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF2415 PF10313.4 EGF98521.1 - 1.4e-11 43.9 0.0 5.7e-11 41.9 0.0 2.2 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EGF98521.1 - 0.0015 18.3 0.3 14 5.7 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat MBOAT_2 PF13813.1 EGF98523.1 - 1.3e-14 53.9 4.2 3.7e-14 52.5 2.9 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Peptidase_C65 PF10275.4 EGF98526.1 - 0.00015 21.1 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EGF98526.1 - 0.0003 21.3 0.0 0.00066 20.2 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease FAR1 PF03101.10 EGF98526.1 - 0.02 15.3 0.0 0.057 13.9 0.0 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain tRNA-synt_1g PF09334.6 EGF98527.1 - 1.9e-144 481.1 0.4 2.4e-144 480.7 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.15 EGF98527.1 - 3.2e-07 29.9 0.4 8.3e-07 28.5 0.3 1.7 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.17 EGF98527.1 - 0.00036 18.6 1.7 0.057 11.4 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGF98527.1 - 0.0004 20.1 0.0 0.0014 18.3 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA V_ATPase_I PF01496.14 EGF98527.1 - 0.16 9.8 0.4 0.24 9.2 0.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNase_HII PF01351.13 EGF98528.1 - 1.1e-51 175.2 0.0 1e-43 149.3 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease HII zf-RING_2 PF13639.1 EGF98530.1 - 1.6e-11 43.8 8.6 2.9e-11 43.0 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGF98530.1 - 3e-05 24.0 3.2 5.9e-05 23.1 2.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGF98530.1 - 5.2e-05 23.1 7.1 0.0001 22.2 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGF98530.1 - 0.00024 20.7 4.8 0.00053 19.5 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) gpUL132 PF11359.3 EGF98530.1 - 0.00024 20.5 0.1 0.00071 18.9 0.1 1.8 1 0 0 1 1 1 1 Glycoprotein UL132 zf-RING_5 PF14634.1 EGF98530.1 - 0.00062 19.4 4.0 0.0013 18.4 2.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGF98530.1 - 0.00067 19.4 2.0 0.0012 18.6 1.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EGF98530.1 - 0.0026 17.6 3.8 0.0059 16.5 2.6 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 EGF98530.1 - 0.0099 15.5 4.0 0.024 14.3 2.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGF98530.1 - 0.053 13.1 8.1 0.096 12.2 5.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EGF98530.1 - 0.092 12.8 4.1 0.17 11.9 2.9 1.5 1 0 0 1 1 1 0 RING-variant domain Sec20 PF03908.8 EGF98531.1 - 3.9e-20 71.3 4.8 9.1e-20 70.1 3.4 1.7 1 0 0 1 1 1 1 Sec20 CP12 PF02672.10 EGF98531.1 - 0.19 12.2 0.2 0.19 12.2 0.1 2.6 3 0 0 3 3 3 0 CP12 domain PNMA PF14893.1 EGF98531.1 - 0.26 10.2 1.8 0.39 9.6 1.2 1.1 1 0 0 1 1 1 0 PNMA MRP-S31 PF15433.1 EGF98531.1 - 1.5 8.1 6.7 2.4 7.4 4.6 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Mito_carr PF00153.22 EGF98532.1 - 2.3e-21 75.3 1.8 7.6e-11 41.5 0.0 3.5 4 0 0 4 4 4 2 Mitochondrial carrier protein DHC_N1 PF08385.7 EGF98536.1 - 7.9e-161 536.3 12.4 1.9e-160 535.0 2.7 3.4 3 1 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 EGF98536.1 - 1.9e-28 99.5 0.0 3.6e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 Response_reg PF00072.19 EGF98536.1 - 0.0015 18.5 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain FYVE_2 PF02318.11 EGF98541.1 - 0.35 10.7 2.8 0.46 10.4 1.9 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger UBN2_2 PF14227.1 EGF98542.1 - 0.00044 19.8 0.1 0.00093 18.7 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGF98542.1 - 0.026 14.3 0.0 0.067 12.9 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Glyco_hydro_14 PF01373.12 EGF98544.1 - 0.15 10.7 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 Acyl_transf_1 PF00698.16 EGF98545.1 - 4.7e-48 164.1 0.0 3.5e-33 115.2 0.0 2.3 1 1 1 2 2 2 2 Acyl transferase domain MaoC_dehydratas PF01575.14 EGF98545.1 - 1.9e-21 75.7 0.0 1.4e-20 72.9 0.0 2.3 3 0 0 3 3 3 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EGF98545.1 - 0.002 17.9 0.5 0.12 12.2 0.4 2.5 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase Mo25 PF08569.6 EGF98546.1 - 2.2e-16 59.8 4.2 9.7e-15 54.4 1.0 2.0 2 0 0 2 2 2 2 Mo25-like VHS PF00790.14 EGF98547.1 - 5.5e-24 84.4 0.8 2e-23 82.5 0.0 2.0 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EGF98547.1 - 1.8e-15 56.5 7.4 3.4e-15 55.6 5.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EGF98547.1 - 4.5e-06 25.7 5.5 0.0013 18.0 1.2 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif HEAT_2 PF13646.1 EGF98547.1 - 0.21 11.8 2.8 2 8.7 0.0 3.1 2 1 0 2 2 2 0 HEAT repeats DUF4206 PF13901.1 EGF98547.1 - 0.5 9.8 4.1 0.97 8.9 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) OrfB_Zn_ribbon PF07282.6 EGF98547.1 - 0.88 9.2 3.4 2 8.1 2.3 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Urb2 PF10441.4 EGF98549.1 - 3.5e-13 49.6 0.7 3.5e-13 49.6 0.5 4.4 4 1 0 4 4 4 1 Urb2/Npa2 family DUF1013 PF06242.6 EGF98549.1 - 0.023 14.6 0.7 22 5.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1013) Homeobox PF00046.24 EGF98550.1 - 8.5e-05 22.1 1.2 0.00021 20.8 0.8 1.7 1 0 0 1 1 1 1 Homeobox domain DOCK-C2 PF14429.1 EGF98551.1 - 3.4e-35 121.3 0.0 5.9e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EGF98551.1 - 1.3e-24 86.4 0.3 9e-23 80.4 0.2 2.9 1 1 0 1 1 1 1 Dedicator of cytokinesis RNA_pol_Rpb1_1 PF04997.7 EGF98552.1 - 1.2e-110 369.9 0.0 1.7e-110 369.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EGF98552.1 - 3.2e-105 351.3 0.0 4.7e-105 350.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGF98552.1 - 3e-68 228.9 0.0 5.3e-68 228.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EGF98552.1 - 7.7e-67 224.6 0.0 1.3e-66 223.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EGF98552.1 - 1.3e-50 171.2 0.0 2.5e-50 170.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EGF98552.1 - 1.7e-45 154.0 2.6 3.8e-45 152.9 1.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EGF98552.1 - 1.1e-38 131.3 0.2 2.3e-38 130.2 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EGF98552.1 - 1.9e-08 33.7 186.7 0.073 13.2 7.9 13.4 12 1 4 16 16 16 13 RNA polymerase Rpb1 C-terminal repeat ABC_sub_bind PF04392.7 EGF98552.1 - 0.06 12.3 0.1 9.7 5.0 0.1 2.3 2 0 0 2 2 2 0 ABC transporter substrate binding protein Pyr_redox PF00070.22 EGF98553.1 - 3.4e-09 36.9 0.0 4.7e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGF98553.1 - 4e-09 36.6 0.0 3e-05 23.9 0.0 3.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGF98553.1 - 7.1e-05 22.9 0.0 0.0013 18.7 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGF98553.1 - 0.00017 21.3 0.1 2.1 8.0 0.0 3.4 3 1 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EGF98553.1 - 0.0019 17.1 0.0 0.0068 15.3 0.0 1.8 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Serpin PF00079.15 EGF98553.1 - 0.018 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) LSM PF01423.17 EGF98554.1 - 3.2e-13 49.0 0.3 7.3e-13 47.8 0.2 1.6 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGF98554.1 - 0.0005 19.9 0.0 0.00077 19.3 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1256 PF06866.6 EGF98554.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) RhoGEF PF00621.15 EGF98559.1 - 8.6e-26 90.9 0.2 8.6e-26 90.9 0.1 2.2 2 0 0 2 2 2 1 RhoGEF domain Ferric_reduct PF01794.14 EGF98560.1 - 9.9e-15 54.7 11.5 9.9e-15 54.7 8.0 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EGF98560.1 - 4.4e-09 36.4 0.2 6.9e-08 32.5 0.1 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGF98560.1 - 0.0005 19.8 0.0 0.0025 17.6 0.0 2.2 2 1 0 2 2 2 1 FAD-binding domain DUF2244 PF10003.4 EGF98560.1 - 0.92 8.8 7.4 0.094 12.0 0.4 2.4 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4470 PF14737.1 EGF98561.1 - 2.2e-12 46.6 0.0 4.9e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EGF98561.1 - 1e-10 41.0 4.0 2.1e-10 40.1 2.8 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EGF98561.1 - 0.0002 21.0 3.2 0.00051 19.7 1.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGF98561.1 - 0.0019 17.7 0.5 0.0019 17.7 0.3 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGF98561.1 - 0.012 15.4 4.0 0.26 11.2 0.1 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGF98561.1 - 0.15 12.7 1.3 0.31 11.7 0.9 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGF98561.1 - 0.15 12.3 1.8 0.34 11.2 1.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGF98561.1 - 0.15 12.7 1.0 0.55 11.0 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGF98561.1 - 0.16 11.8 1.0 4.2 7.4 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat NAD_binding_6 PF08030.7 EGF98562.1 - 6.2e-15 55.4 0.1 1.1e-13 51.4 0.1 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGF98562.1 - 2.2e-14 53.2 0.0 4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGF98562.1 - 4.9e-11 42.7 7.3 9.2e-11 41.9 5.1 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EGF98562.1 - 0.039 14.5 0.0 0.6 10.7 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain FLO_LFY PF01698.11 EGF98563.1 - 1.3 7.7 6.0 1.8 7.3 4.2 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein COX15-CtaA PF02628.10 EGF98565.1 - 5.3e-08 32.0 0.0 5.7e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein JmjC PF02373.17 EGF98566.1 - 2.6e-11 43.7 0.1 3.3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EGF98566.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain NAD_binding_6 PF08030.7 EGF98567.1 - 9.3e-27 93.8 0.0 1.6e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGF98567.1 - 3.4e-19 68.6 0.0 7.4e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGF98567.1 - 1e-06 28.8 13.3 8.7e-06 25.8 9.2 2.1 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGF98567.1 - 0.002 18.2 0.0 0.0047 17.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF4470 PF14737.1 EGF98567.1 - 0.01 15.5 0.0 0.069 12.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4470) NAD_binding_1 PF00175.16 EGF98567.1 - 0.031 14.8 0.0 0.17 12.4 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain ERG4_ERG24 PF01222.12 EGF98568.1 - 1e-113 380.1 20.1 1.2e-113 379.9 14.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGF98568.1 - 0.00025 20.4 0.7 0.00084 18.6 0.5 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Transaldolase PF00923.14 EGF98570.1 - 1.5e-94 316.3 0.0 1.7e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 Transaldolase DUF1062 PF06353.7 EGF98570.1 - 0.027 14.6 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) Peptidase_M20 PF01546.23 EGF98572.1 - 3.5e-32 111.4 0.0 4.7e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGF98572.1 - 1.4e-15 56.9 0.0 2.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain p450 PF00067.17 EGF98573.1 - 8.8e-17 60.7 0.0 2.6e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Acetyltransf_1 PF00583.19 EGF98575.1 - 1.6e-14 53.6 0.0 2.2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGF98575.1 - 2.5e-09 37.1 0.2 5.5e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGF98575.1 - 3.9e-08 33.4 0.0 4.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGF98575.1 - 1.6e-05 24.8 0.0 1.9e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGF98575.1 - 5.9e-05 22.7 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EGF98575.1 - 0.0003 20.6 0.0 0.00039 20.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGF98575.1 - 0.0092 16.1 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EGF98575.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF3749 PF12568.3 EGF98575.1 - 0.022 14.3 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGF98575.1 - 0.026 14.3 0.2 0.054 13.3 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pho86 PF11124.3 EGF98575.1 - 0.07 12.1 0.0 0.077 11.9 0.0 1.1 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Acetyltransf_CG PF14542.1 EGF98575.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Amino_oxidase PF01593.19 EGF98576.1 - 5.4e-19 68.5 0.0 2.6e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGF98576.1 - 1.7e-13 50.3 0.0 4.3e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGF98576.1 - 2.7e-13 49.5 0.0 4.4e-06 25.8 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGF98576.1 - 0.00026 21.1 0.0 0.088 12.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGF98576.1 - 0.00037 19.4 0.4 0.0028 16.5 0.8 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGF98576.1 - 0.00056 19.8 0.0 0.0012 18.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGF98576.1 - 0.0007 19.9 0.6 0.036 14.4 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGF98576.1 - 0.00079 18.6 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGF98576.1 - 0.039 13.0 0.6 0.063 12.3 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EGF98576.1 - 0.048 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDI PF00996.13 EGF98576.1 - 0.055 11.7 0.0 0.36 9.0 0.0 1.9 2 0 0 2 2 2 0 GDP dissociation inhibitor NAD_binding_9 PF13454.1 EGF98576.1 - 0.11 12.3 0.1 0.75 9.5 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EGF98576.1 - 0.14 11.2 0.1 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EGF98576.1 - 0.18 10.2 0.1 2.1 6.7 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein Arena_nucleocap PF00843.12 EGF98576.1 - 0.21 9.3 0.0 0.33 8.7 0.0 1.1 1 0 0 1 1 1 0 Arenavirus nucleocapsid protein Glyco_transf_22 PF03901.12 EGF98578.1 - 9.1e-32 110.5 27.6 8.7e-31 107.3 19.1 2.0 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Thaumatin PF00314.12 EGF98579.1 - 6.6e-21 74.7 2.6 8e-21 74.4 1.8 1.0 1 0 0 1 1 1 1 Thaumatin family MNSV_P7B PF06692.6 EGF98579.1 - 0.074 12.8 0.3 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein Glyco_transf_22 PF03901.12 EGF98582.1 - 1.1e-85 288.1 24.7 1.4e-85 287.8 17.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Totivirus_coat PF05518.6 EGF98583.1 - 0.97 7.1 6.7 1.3 6.7 4.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein DUF755 PF05501.6 EGF98588.1 - 0.0025 17.8 17.8 0.0025 17.8 12.4 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF755) DNA_pol_viral_N PF00242.12 EGF98588.1 - 0.98 8.3 13.3 1.2 8.1 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain AvrE PF11725.3 EGF98588.1 - 1.7 5.5 14.1 1.9 5.4 9.8 1.0 1 0 0 1 1 1 0 Pathogenicity factor Peptidase_S49_N PF08496.5 EGF98588.1 - 3.5 7.3 7.2 6.7 6.4 5.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Macoilin PF09726.4 EGF98588.1 - 3.9 5.6 13.3 4.1 5.5 9.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 EGF98588.1 - 5 4.6 10.8 6 4.4 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cwf_Cwc_15 PF04889.7 EGF98588.1 - 8.1 6.0 24.3 0.17 11.5 12.4 1.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Galactosyl_T PF01762.16 EGF98589.1 - 2.3e-09 37.1 0.0 0.004 16.7 0.0 3.3 2 1 1 3 3 3 3 Galactosyltransferase DUF3357 PF11837.3 EGF98589.1 - 0.057 13.2 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) PUF PF00806.14 EGF98590.1 - 1.4e-52 172.3 3.2 1.4e-06 27.4 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat BCIP PF13862.1 EGF98590.1 - 0.0011 18.5 0.9 0.0022 17.5 0.1 1.9 2 0 0 2 2 2 1 p21-C-terminal region-binding protein DAGK_cat PF00781.19 EGF98591.1 - 5.7e-24 83.9 0.2 8.7e-24 83.4 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF21 PF01595.15 EGF98601.1 - 9e-37 126.1 0.2 1.3e-36 125.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EGF98601.1 - 0.00042 20.0 0.3 1.1 9.1 0.0 3.8 3 0 0 3 3 3 2 CBS domain Glyco_hydro_81 PF03639.8 EGF98604.1 - 9.7e-129 430.4 5.4 4.8e-128 428.1 3.7 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 HTH_32 PF13565.1 EGF98605.1 - 0.0033 18.2 1.2 1.3 9.8 0.0 2.9 2 1 1 3 3 3 2 Homeodomain-like domain HTH_38 PF13936.1 EGF98605.1 - 0.0096 15.4 0.3 0.037 13.5 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain MerR_1 PF13411.1 EGF98605.1 - 0.06 13.1 0.2 16 5.3 0.0 2.6 3 0 0 3 3 3 0 MerR HTH family regulatory protein PI3_PI4_kinase PF00454.22 EGF98606.1 - 3.9e-10 39.5 0.0 4.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Kazal_2 PF07648.10 EGF98606.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain UBN2 PF14223.1 EGF98607.1 - 0.00053 19.7 0.7 0.00082 19.1 0.5 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EGF98607.1 - 0.011 15.2 0.3 0.61 9.6 0.2 2.5 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type HTH_19 PF12844.2 EGF98607.1 - 0.039 14.0 0.3 0.59 10.2 0.2 2.4 1 1 0 1 1 1 0 Helix-turn-helix domain UBN2_2 PF14227.1 EGF98607.1 - 0.048 13.2 0.8 0.085 12.4 0.6 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Erg28 PF03694.8 EGF98609.1 - 6.4e-38 129.1 2.0 7.4e-38 128.9 1.4 1.0 1 0 0 1 1 1 1 Erg28 like protein NAD_binding_8 PF13450.1 EGF98610.1 - 3e-11 43.1 0.4 6.4e-11 42.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGF98610.1 - 9.3e-09 34.8 0.0 5.6e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EGF98610.1 - 0.00024 21.2 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGF98610.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGF98610.1 - 0.0022 16.9 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGF98610.1 - 0.0035 17.1 0.1 0.0084 15.9 0.1 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EGF98610.1 - 0.0045 16.0 0.1 0.0072 15.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EGF98610.1 - 0.015 14.1 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EGF98610.1 - 0.025 14.5 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 EGF98610.1 - 0.026 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 EGF98610.1 - 0.04 12.9 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.1 EGF98610.1 - 0.062 12.2 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EGF98610.1 - 0.076 11.4 0.1 0.11 10.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF4611 PF15387.1 EGF98612.1 - 0.058 13.5 0.8 0.13 12.3 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Resolvase PF00239.16 EGF98613.1 - 0.095 12.5 1.6 0.19 11.6 1.1 1.5 1 0 0 1 1 1 0 Resolvase, N terminal domain STE3 PF02076.10 EGF98614.1 - 2.7e-65 220.2 5.9 3.4e-65 219.9 4.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF4234 PF14018.1 EGF98614.1 - 0.029 14.0 1.8 0.066 12.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) RP-C_C PF11800.3 EGF98619.1 - 0.17 11.5 2.3 0.38 10.4 1.6 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region FAR1 PF03101.10 EGF98619.1 - 0.35 11.4 0.1 0.35 11.4 0.1 2.1 2 0 0 2 2 2 0 FAR1 DNA-binding domain Nucleo_P87 PF07267.6 EGF98619.1 - 0.52 8.9 7.1 0.91 8.1 4.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3827 PF12877.2 EGF98622.1 - 0.39 8.7 4.1 0.82 7.6 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) RP-C_C PF11800.3 EGF98628.1 - 1.4 8.5 5.5 0.36 10.5 1.6 1.6 2 0 0 2 2 2 0 Replication protein C C-terminal region Nucleo_P87 PF07267.6 EGF98628.1 - 6 5.4 11.2 0.85 8.2 4.9 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 FAR1 PF03101.10 EGF98629.1 - 0.0014 19.0 0.1 0.0014 19.0 0.1 2.0 2 0 0 2 2 2 1 FAR1 DNA-binding domain EF-hand_7 PF13499.1 EGF98629.1 - 0.13 12.3 0.1 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Gp_dh_N PF00044.19 EGF98632.1 - 3e-51 173.3 0.7 4.5e-50 169.5 0.1 2.2 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 EGF98632.1 - 5.9e-48 162.2 0.0 1.2e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DUF2436 PF10365.4 EGF98632.1 - 0.011 15.4 0.2 0.022 14.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2436) CBM_4_9 PF02018.12 EGF98632.1 - 0.074 13.0 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain DapB_N PF01113.15 EGF98632.1 - 0.12 12.3 0.2 0.38 10.6 0.1 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EGF98632.1 - 0.12 11.5 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WIF PF02019.13 EGF98633.1 - 0.004 16.6 0.1 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 WIF domain UBN2_2 PF14227.1 EGF98633.1 - 0.0073 15.8 5.1 0.011 15.2 1.0 2.9 3 1 0 3 3 3 1 gag-polypeptide of LTR copia-type Spore_GerAC PF05504.6 EGF98633.1 - 0.015 15.0 0.6 0.035 13.8 0.4 1.7 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal DUF3921 PF13060.1 EGF98633.1 - 0.062 13.1 0.2 0.47 10.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3921) DUF972 PF06156.8 EGF98634.1 - 0.51 10.7 2.4 2.6 8.4 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) LTV PF04180.9 EGF98637.1 - 0.06 12.8 0.1 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Low temperature viability protein DUF2206 PF09971.4 EGF98641.1 - 0.6 8.8 4.1 1 8.1 2.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Pkinase PF00069.20 EGF98645.1 - 2e-71 240.1 0.0 2.4e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF98645.1 - 9.1e-30 103.5 0.0 1.4e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGF98645.1 - 3.7e-06 26.1 0.0 2.6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGF98645.1 - 0.0037 16.6 0.1 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EGF98645.1 - 0.028 13.4 0.4 0.069 12.2 0.3 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGF98645.1 - 0.033 13.9 0.3 0.093 12.4 0.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family YukC PF10140.4 EGF98645.1 - 0.073 11.6 0.0 0.094 11.2 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC gag-asp_proteas PF13975.1 EGF98646.1 - 0.019 14.7 0.0 0.058 13.2 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF2203 PF09969.4 EGF98646.1 - 0.1 12.8 1.6 0.36 11.0 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Asp_protease_2 PF13650.1 EGF98646.1 - 0.13 12.8 0.0 0.46 11.0 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease Syntaxin_2 PF14523.1 EGF98646.1 - 0.16 11.9 7.9 0.69 9.9 5.2 2.3 1 1 0 1 1 1 0 Syntaxin-like protein NAD_binding_1 PF00175.16 EGF98647.1 - 3.2e-09 37.3 0.0 8e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGF98647.1 - 4.2e-06 26.8 0.0 8.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGF98647.1 - 6.6e-06 26.1 0.1 0.00078 19.3 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain RNase_H2-Ydr279 PF09468.5 EGF98649.1 - 8.5e-06 25.1 4.9 1e-05 24.9 3.4 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) T3SS_LEE_assoc PF13327.1 EGF98649.1 - 0.02 14.4 0.2 0.029 13.9 0.1 1.2 1 0 0 1 1 1 0 Type III secretion system subunit THUMP PF02926.12 EGF98649.1 - 0.048 13.5 0.1 0.064 13.1 0.1 1.1 1 0 0 1 1 1 0 THUMP domain FHA PF00498.21 EGF98650.1 - 4.3e-13 49.1 1.1 9.4e-13 48.0 0.1 2.2 2 0 0 2 2 2 1 FHA domain zf-RING_2 PF13639.1 EGF98650.1 - 1.3e-07 31.3 13.4 2.1e-07 30.6 9.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGF98650.1 - 0.00018 21.5 6.0 0.00036 20.5 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGF98650.1 - 0.015 14.9 12.2 0.026 14.1 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGF98650.1 - 0.023 14.5 5.7 0.041 13.7 4.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EGF98650.1 - 0.39 10.4 12.0 0.86 9.3 8.3 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGF98650.1 - 0.78 9.8 14.6 1.4 9.0 10.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EGF98650.1 - 0.81 9.4 8.2 1.6 8.5 5.7 1.4 1 0 0 1 1 1 0 PHD-finger Lant_dehyd_C PF04738.8 EGF98651.1 - 0.09 10.9 0.3 0.14 10.4 0.1 1.3 2 0 0 2 2 2 0 Lantibiotic dehydratase, C terminus DZR PF12773.2 EGF98652.1 - 0.42 10.4 8.4 1.4 8.7 5.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_L37e PF01907.14 EGF98652.1 - 0.97 9.2 6.7 0.11 12.2 1.5 1.7 2 0 0 2 2 2 0 Ribosomal protein L37e Glycos_transf_2 PF00535.21 EGF98653.1 - 5.6e-21 74.9 0.1 1.8e-20 73.3 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGF98653.1 - 1.3e-07 31.7 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EGF98653.1 - 0.1 11.6 0.0 0.28 10.2 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Ribosomal_L28 PF00830.14 EGF98654.1 - 4e-20 71.4 1.0 9.9e-20 70.1 0.1 2.1 2 0 0 2 2 2 1 Ribosomal L28 family 2OG-FeII_Oxy PF03171.15 EGF98655.1 - 1.8e-16 60.2 0.1 2.8e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGF98655.1 - 8e-16 58.6 0.0 1.7e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Mss4 PF04421.8 EGF98657.1 - 0.0036 17.1 0.1 0.0073 16.1 0.1 1.5 1 0 0 1 1 1 1 Mss4 protein Amidohydro_1 PF01979.15 EGF98658.1 - 7e-20 71.9 0.0 4.9e-19 69.1 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGF98658.1 - 5.8e-14 52.7 0.0 3.4e-13 50.2 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EGF98658.1 - 3.5e-09 36.3 0.0 8.8e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGF98658.1 - 0.005 16.1 0.0 2.2 7.4 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.9 EGF98658.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 1 1 0 1 1 1 0 Amidohydrolase Aldolase_II PF00596.16 EGF98659.1 - 2e-42 144.8 0.0 2.3e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain CoA_trans PF01144.18 EGF98661.1 - 4.5e-104 346.3 0.1 2.8e-59 199.9 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EGF98661.1 - 0.01 15.4 0.1 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Sel1 PF08238.7 EGF98662.1 - 8.8e-11 42.0 2.7 7.2e-08 32.8 0.3 3.2 3 0 0 3 3 3 2 Sel1 repeat HLH PF00010.21 EGF98663.1 - 3.1e-11 42.7 0.1 1.5e-10 40.5 0.0 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Snf7 PF03357.16 EGF98664.1 - 5.1e-30 104.1 26.4 5.1e-30 104.1 18.3 1.4 1 1 0 1 1 1 1 Snf7 DUF2428 PF10350.4 EGF98664.1 - 0.014 14.4 1.3 0.018 14.0 0.9 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) FdhE PF04216.7 EGF98664.1 - 0.23 11.1 2.9 0.3 10.7 2.0 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF607 PF04678.8 EGF98664.1 - 0.52 10.2 11.3 20 5.0 7.7 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF607 DUF1824 PF08854.5 EGF98664.1 - 0.97 9.0 5.2 0.4 10.3 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1824) Alpha-mann_mid PF09261.6 EGF98664.1 - 1.1 9.5 8.7 8 6.7 1.3 2.5 2 0 0 2 2 2 0 Alpha mannosidase, middle domain Trypan_glycop PF00913.14 EGF98664.1 - 3.3 6.5 10.5 0.17 10.7 1.7 2.1 2 1 0 2 2 2 0 Trypanosome variant surface glycoprotein (A-type) FAD_binding_3 PF01494.14 EGF98665.1 - 4.4e-93 312.1 0.0 1.3e-92 310.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGF98665.1 - 2.4e-50 170.4 0.0 3.9e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 EGF98665.1 - 2.1e-05 23.7 0.1 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EGF98665.1 - 3e-05 23.0 0.6 4.9e-05 22.3 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGF98665.1 - 5.6e-05 21.7 0.2 9.6e-05 21.0 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EGF98665.1 - 6.5e-05 22.8 0.3 0.00018 21.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 EGF98665.1 - 0.00013 21.8 0.1 0.00023 21.0 0.1 1.4 1 0 0 1 1 1 1 ThiF family Pyr_redox_2 PF07992.9 EGF98665.1 - 0.00029 20.7 0.2 0.0029 17.5 0.1 2.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGF98665.1 - 0.00064 18.7 0.1 0.0011 17.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGF98665.1 - 0.00067 18.4 0.2 0.0012 17.6 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EGF98665.1 - 0.0035 16.3 0.2 0.0073 15.2 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 EGF98665.1 - 0.0079 15.0 0.3 0.013 14.4 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EGF98665.1 - 0.0088 16.1 0.2 0.023 14.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGF98665.1 - 0.018 14.1 0.7 0.033 13.2 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGF98665.1 - 0.03 14.0 0.1 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EGF98665.1 - 0.032 13.5 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 EGF98665.1 - 0.039 14.3 0.2 0.075 13.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EGF98665.1 - 0.094 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EGF98665.1 - 0.14 11.5 0.3 0.26 10.7 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA N-glycanase_C PF09113.5 EGF98666.1 - 0.043 13.4 0.7 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Peptide-N-glycosidase F, C terminal ARD PF03079.9 EGF98668.1 - 3.2e-46 157.1 1.0 3.9e-46 156.8 0.7 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EGF98668.1 - 2.3e-09 36.6 0.0 5.3e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EGF98668.1 - 1.1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EGF98668.1 - 0.0062 15.9 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EGF98668.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF1498 PF07385.7 EGF98668.1 - 0.072 12.2 0.0 0.21 10.6 0.0 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1498) LisH PF08513.6 EGF98670.1 - 6.5e-06 25.7 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 LisH WD40 PF00400.27 EGF98671.1 - 2.7e-52 172.8 19.4 3.9e-10 39.2 0.1 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EGF98671.1 - 1.2e-09 37.7 0.1 4e-09 36.0 0.1 2.0 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EGF98671.1 - 6e-06 24.6 2.9 0.22 9.6 0.0 4.4 2 1 2 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.28 EGF98671.1 - 0.0012 18.4 2.1 0.0012 18.4 0.1 2.1 2 0 0 2 2 2 1 F-box domain PQQ_3 PF13570.1 EGF98671.1 - 0.0096 16.1 7.9 8.7 6.7 0.0 5.5 4 2 2 6 6 6 1 PQQ-like domain Nucleoporin_N PF08801.6 EGF98671.1 - 0.061 12.0 2.8 0.25 10.0 0.0 2.9 2 1 0 3 3 3 0 Nup133 N terminal like PHD PF00628.24 EGF98673.1 - 1.4e-07 31.0 0.7 3.1e-07 29.9 0.5 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EGF98673.1 - 0.051 13.3 0.3 0.085 12.6 0.2 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EGF98673.1 - 0.51 10.1 1.0 0.9 9.3 0.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 SH3_9 PF14604.1 EGF98674.1 - 1.7e-25 88.3 1.5 4.8e-13 48.4 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EGF98674.1 - 8e-23 79.5 3.2 1.2e-11 43.7 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EGF98674.1 - 1.1e-14 53.6 0.1 7.7e-07 28.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EGF98674.1 - 2.7e-14 53.1 0.0 4.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Lactamase_B_2 PF12706.2 EGF98675.1 - 1.6e-34 119.1 0.1 3.1e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGF98675.1 - 5.5e-13 48.9 0.0 9.3e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGF98675.1 - 0.0049 16.5 0.0 0.021 14.4 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF1816 PF08846.5 EGF98675.1 - 0.051 13.2 0.3 0.55 9.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1816) RRM_1 PF00076.17 EGF98676.1 - 2.8e-15 55.7 0.0 7.1e-15 54.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGF98676.1 - 5.3e-12 45.5 0.1 2.8e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGF98676.1 - 1.4e-09 37.6 0.1 2.5e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TEA PF01285.13 EGF98677.1 - 4e-23 82.2 0.1 3.5e-22 79.1 0.0 2.1 2 0 0 2 2 2 1 TEA/ATTS domain family SAM_2 PF07647.12 EGF98678.1 - 5.7e-10 38.9 0.0 1.9e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGF98678.1 - 8.5e-07 29.0 0.0 2.2e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 EGF98678.1 - 0.00029 20.3 0.1 0.023 14.2 0.1 3.1 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.12 EGF98678.1 - 0.0006 19.2 0.2 0.011 15.2 0.0 2.8 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.23 EGF98678.1 - 0.00084 18.6 0.0 0.26 10.6 0.0 2.8 3 0 0 3 3 3 2 SH3 domain SAM_PNT PF02198.11 EGF98678.1 - 0.0038 16.9 0.0 0.014 15.1 0.0 2.0 1 1 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Alpha_kinase PF02816.13 EGF98679.1 - 1.3e-11 44.5 0.0 2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family NAD_binding_8 PF13450.1 EGF98680.1 - 2.7e-05 24.1 0.0 0.00025 20.9 0.0 2.4 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain EcoRI PF02963.11 EGF98683.1 - 0.16 10.7 0.0 0.57 8.9 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease EcoRI XPA_C PF05181.7 EGF98685.1 - 7.1e-28 95.9 2.7 7.1e-28 95.9 1.9 2.0 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 EGF98685.1 - 0.0023 17.5 2.1 0.0032 17.1 0.1 2.1 2 0 0 2 2 2 1 XPA protein N-terminal Zn-ribbon_8 PF09723.5 EGF98685.1 - 3.2 7.7 7.1 4.2 7.3 0.1 3.0 2 1 1 3 3 3 0 Zinc ribbon domain ABC_tran_2 PF12848.2 EGF98685.1 - 4.5 7.1 15.2 1.6 8.6 1.0 2.4 2 0 0 2 2 2 0 ABC transporter Mastoparan_2 PF08251.6 EGF98687.1 - 0.21 11.6 2.1 0.58 10.3 0.1 2.5 2 0 0 2 2 2 0 Mastoparan peptide FAD_binding_8 PF08022.7 EGF98688.1 - 1.3e-20 73.2 0.0 2.2e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGF98688.1 - 4.8e-07 29.9 1.2 8.7e-07 29.0 0.8 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EGF98688.1 - 0.00014 21.8 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EGF98688.1 - 0.00017 21.6 0.0 0.00068 19.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain 2TM PF13239.1 EGF98688.1 - 0.043 13.8 0.2 0.094 12.7 0.2 1.5 1 0 0 1 1 1 0 2TM domain MTS PF05175.9 EGF98691.1 - 1.4e-05 24.5 0.2 0.029 13.7 0.0 2.3 1 1 0 2 2 2 2 Methyltransferase small domain Methyltransf_16 PF10294.4 EGF98691.1 - 0.0067 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EGF98691.1 - 0.0091 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGF98691.1 - 0.011 15.7 0.3 0.69 9.9 0.0 2.2 1 1 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EGF98691.1 - 0.039 14.5 0.2 0.097 13.2 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Vfa1 PF08432.5 EGF98692.1 - 1.9 8.4 7.0 2.8 7.9 4.8 1.3 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDE_Tnp_1_assoc PF13808.1 EGF98693.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-associated RRM_1 PF00076.17 EGF98694.1 - 6.4e-29 99.3 0.0 1.6e-15 56.4 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGF98694.1 - 1.1e-22 79.7 0.0 1.1e-10 41.2 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGF98694.1 - 8e-14 51.2 0.1 5.2e-05 23.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EGF98694.1 - 0.0084 15.7 0.2 0.12 12.0 0.0 2.6 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EGF98694.1 - 0.088 12.5 0.6 9.8 6.0 0.0 3.1 3 0 0 3 3 3 0 Limkain b1 Het-C PF07217.6 EGF98696.1 - 2.8e-203 676.4 0.0 4.4e-203 675.8 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF1987 PF09345.5 EGF98698.1 - 0.15 11.8 0.2 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Dor1 PF04124.7 EGF98698.1 - 0.17 10.2 0.1 0.33 9.3 0.1 1.3 1 0 0 1 1 1 0 Dor1-like family F-box-like_2 PF13013.1 EGF98699.1 - 0.0083 15.8 1.3 0.39 10.4 0.0 2.5 2 1 0 2 2 2 2 F-box-like domain LRR_4 PF12799.2 EGF98699.1 - 0.57 9.8 7.3 11 5.8 0.2 4.8 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) STE PF02200.11 EGF98701.1 - 5.6e-56 187.4 0.2 2e-55 185.6 0.0 1.8 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 EGF98701.1 - 4e-12 45.7 8.9 1e-05 25.5 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGF98701.1 - 5.1e-09 35.9 17.6 1.2e-08 34.8 3.7 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGF98701.1 - 7.1e-08 32.2 8.5 0.0027 17.9 1.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGF98701.1 - 0.011 15.9 1.5 0.085 13.0 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGF98701.1 - 0.044 13.7 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger TerY-C PF15616.1 EGF98702.1 - 0.11 12.4 1.1 0.23 11.3 0.8 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain DUF1640 PF07798.6 EGF98704.1 - 9.3e-15 55.1 0.5 1.4e-14 54.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Apolipoprotein PF01442.13 EGF98704.1 - 0.012 15.1 3.4 0.02 14.3 2.4 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain AKNA PF12443.3 EGF98704.1 - 0.045 13.7 0.7 7.1 6.7 0.2 2.7 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF948 PF06103.6 EGF98704.1 - 0.081 12.7 5.1 1.8 8.4 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3864 PF12980.2 EGF98704.1 - 1.4 9.2 3.6 0.6 10.3 0.2 2.0 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) Acyl-CoA_dh_1 PF00441.19 EGF98705.1 - 2.5e-31 108.7 0.5 3.7e-31 108.2 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGF98705.1 - 3e-15 55.4 0.0 7.1e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EGF98705.1 - 3.6e-12 46.8 0.0 9.3e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGF98705.1 - 1.1e-10 41.9 0.2 1.7e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EGF98705.1 - 0.0026 17.1 0.0 0.0073 15.7 0.0 1.6 2 0 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CDC37_N PF03234.9 EGF98706.1 - 2.2e-43 148.6 12.7 2.2e-43 148.6 8.8 2.3 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EGF98706.1 - 1.1e-35 122.7 0.0 1.1e-35 122.7 0.0 2.9 4 0 0 4 4 4 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EGF98706.1 - 1.7e-20 72.7 4.7 1.7e-20 72.7 3.3 2.6 3 0 0 3 3 3 1 Cdc37 C terminal domain PP2C_C PF07830.8 EGF98706.1 - 0.058 13.5 1.5 0.24 11.5 0.1 2.6 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF1993 PF09351.5 EGF98706.1 - 0.26 11.1 3.2 0.25 11.2 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) Sedlin_N PF04628.8 EGF98709.1 - 3.6e-29 101.2 0.0 4.4e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EGF98709.1 - 0.0058 16.3 0.2 0.02 14.6 0.1 1.9 1 1 0 1 1 1 1 Sybindin-like family DDE_3 PF13358.1 EGF98710.1 - 8.2e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease NAM-associated PF14303.1 EGF98713.1 - 0.05 13.9 2.3 0.066 13.5 1.6 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain TTSSLRR PF12468.3 EGF98717.1 - 0.16 11.4 0.5 0.47 10.0 0.4 1.8 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein Ribosomal_L27 PF01016.14 EGF98718.1 - 2e-31 107.5 1.1 3e-31 107.0 0.7 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein NifU_N PF01592.11 EGF98719.1 - 1.5e-51 173.6 0.3 3.2e-51 172.5 0.0 1.6 2 0 0 2 2 2 1 NifU-like N terminal domain Pex14_N PF04695.8 EGF98721.1 - 5.3e-23 81.5 0.5 4.6e-17 62.3 0.1 4.3 2 2 1 3 3 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.4 EGF98721.1 - 2.3e-05 24.5 6.0 3.6e-05 23.9 4.1 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein IncA PF04156.9 EGF98721.1 - 3.3e-05 23.5 6.4 6.2e-05 22.6 4.5 1.4 1 0 0 1 1 1 1 IncA protein DUF1664 PF07889.7 EGF98721.1 - 0.00023 20.9 0.5 0.00049 19.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) UPF0240 PF06784.6 EGF98721.1 - 0.002 17.8 3.5 0.002 17.8 2.4 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0240) Atg14 PF10186.4 EGF98721.1 - 0.0043 16.0 5.7 0.0067 15.4 4.0 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 LPP PF04728.8 EGF98721.1 - 0.0099 15.6 0.1 0.044 13.5 0.0 2.1 2 0 0 2 2 1 1 Lipoprotein leucine-zipper DUF342 PF03961.8 EGF98721.1 - 0.017 13.5 7.1 0.023 13.1 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Laminin_I PF06008.9 EGF98721.1 - 0.018 14.3 10.5 0.029 13.6 7.2 1.2 1 0 0 1 1 1 0 Laminin Domain I DUF16 PF01519.11 EGF98721.1 - 0.043 14.0 9.1 0.1 12.8 6.3 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 AAA_13 PF13166.1 EGF98721.1 - 0.061 11.7 10.3 0.095 11.1 7.1 1.2 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.6 EGF98721.1 - 0.11 12.8 10.2 0.48 10.8 1.7 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF3584 PF12128.3 EGF98721.1 - 0.12 9.7 10.6 0.16 9.2 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CHASE3 PF05227.8 EGF98721.1 - 0.16 11.6 6.3 0.49 10.0 1.9 2.8 2 1 1 3 3 3 0 CHASE3 domain DUF4164 PF13747.1 EGF98721.1 - 0.17 12.0 9.6 2 8.6 2.9 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) Fib_alpha PF08702.5 EGF98721.1 - 0.23 11.5 13.9 1.8 8.7 5.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.10 EGF98721.1 - 0.37 9.9 9.0 0.58 9.2 6.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Reo_sigmaC PF04582.7 EGF98721.1 - 0.38 9.9 5.1 0.25 10.4 2.3 1.5 2 0 0 2 2 1 0 Reovirus sigma C capsid protein BCAS2 PF05700.6 EGF98721.1 - 0.47 9.8 10.6 0.62 9.4 6.9 1.5 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Prominin PF05478.6 EGF98721.1 - 0.53 7.7 6.0 0.72 7.3 4.1 1.1 1 0 0 1 1 1 0 Prominin Sipho_Gp157 PF05565.6 EGF98721.1 - 0.66 9.5 13.1 0.088 12.3 2.1 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 DUF4200 PF13863.1 EGF98721.1 - 0.79 9.6 16.1 1.6 8.6 11.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.7 EGF98721.1 - 1.3 8.8 8.7 1.1 9.1 3.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3552 PF12072.3 EGF98721.1 - 1.4 8.0 15.1 2.5 7.2 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Tup_N PF08581.5 EGF98721.1 - 1.5 9.0 14.2 1.8 8.7 6.9 2.8 2 1 1 3 3 3 0 Tup N-terminal V_ATPase_I PF01496.14 EGF98721.1 - 2.1 6.1 9.6 3 5.5 6.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.6 EGF98721.1 - 2.6 7.9 8.5 0.89 9.4 0.7 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.8 EGF98721.1 - 2.6 7.0 7.8 3.8 6.4 5.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein APG6 PF04111.7 EGF98721.1 - 3.2 6.7 15.6 4.9 6.0 10.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_32 PF13654.1 EGF98721.1 - 4.2 5.9 11.9 1.5 7.4 5.4 1.9 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EGF98722.1 - 1e-34 119.8 50.8 4.1e-33 114.5 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3753 PF12575.3 EGF98722.1 - 0.058 13.1 3.5 1.3 8.8 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Fz PF01392.17 EGF98722.1 - 0.4 11.0 1.4 0.89 9.9 0.2 2.0 2 0 0 2 2 2 0 Fz domain AhpC-TSA PF00578.16 EGF98726.1 - 3e-33 114.1 0.0 3.9e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EGF98726.1 - 1.7e-12 46.7 0.0 2.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EGF98726.1 - 1.2e-09 37.8 0.0 1.8e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin Prp31_C PF09785.4 EGF98727.1 - 5.4e-41 139.9 3.6 1.3e-40 138.7 2.3 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 EGF98727.1 - 1.2e-37 128.5 0.3 2.5e-37 127.4 0.2 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGF98727.1 - 8.4e-18 63.9 0.1 3.9e-17 61.8 0.1 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain zf-LYAR PF08790.6 EGF98728.1 - 6.1e-12 45.0 3.3 6.1e-12 45.0 2.3 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.3 EGF98728.1 - 0.00081 19.4 1.0 0.0053 16.8 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EGF98728.1 - 0.0081 16.4 0.5 0.0081 16.4 0.3 3.1 4 1 0 4 4 4 1 Zinc finger, C2H2 type IBR PF01485.16 EGF98728.1 - 0.13 12.1 3.9 0.2 11.5 2.7 1.4 1 0 0 1 1 1 0 IBR domain zf-met PF12874.2 EGF98728.1 - 0.21 11.8 0.6 0.21 11.8 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type OrfB_Zn_ribbon PF07282.6 EGF98728.1 - 0.56 9.9 3.2 0.71 9.5 1.6 1.8 1 1 0 1 1 1 0 Putative transposase DNA-binding domain C1_4 PF07975.7 EGF98728.1 - 1.5 8.8 6.7 1.7 8.7 3.1 2.2 1 1 2 3 3 3 0 TFIIH C1-like domain MHYT PF03707.11 EGF98729.1 - 0.0002 21.3 13.2 0.0027 17.8 1.6 2.8 1 1 2 3 3 3 2 Bacterial signalling protein N terminal repeat MHYT PF03707.11 EGF98730.1 - 0.0087 16.1 8.3 3.2 7.9 0.1 4.3 4 0 0 4 4 4 2 Bacterial signalling protein N terminal repeat zf-FPG_IleRS PF06827.9 EGF98732.1 - 0.038 13.6 0.4 0.13 11.8 0.3 1.9 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Med8 PF10232.4 EGF98733.1 - 7.9e-07 28.8 0.5 6.9e-06 25.7 0.3 2.1 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Pox_VLTF3 PF04947.9 EGF98733.1 - 0.051 13.0 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Semialdhyde_dhC PF02774.13 EGF98735.1 - 3e-29 102.1 0.0 1.1e-28 100.3 0.0 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EGF98735.1 - 1.7e-28 99.3 0.0 3.1e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 EGF98735.1 - 0.0008 18.8 0.1 0.049 13.0 0.0 2.6 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DapB_N PF01113.15 EGF98735.1 - 0.0018 18.1 0.0 0.0044 16.9 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 EGF98735.1 - 0.0022 18.5 0.1 0.008 16.7 0.0 2.0 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Ras PF00071.17 EGF98737.1 - 3e-64 215.2 1.3 3.6e-64 215.0 0.9 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGF98737.1 - 2.8e-19 69.7 0.0 4.7e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGF98737.1 - 1.3e-16 60.3 0.3 1.6e-16 60.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGF98737.1 - 1.2e-06 27.8 0.1 1.5e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGF98737.1 - 6.1e-06 25.7 0.3 1.3e-05 24.7 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGF98737.1 - 1.8e-05 24.0 0.1 2.3e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGF98737.1 - 5.4e-05 23.1 0.1 9.3e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGF98737.1 - 0.00057 20.0 0.0 0.0012 18.9 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EGF98737.1 - 0.0035 17.3 0.5 0.087 12.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EGF98737.1 - 0.0071 16.0 0.0 0.014 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) FeoB_N PF02421.13 EGF98737.1 - 0.014 14.6 0.1 0.1 11.8 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 EGF98737.1 - 0.019 15.1 0.1 1.2 9.3 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EGF98737.1 - 0.021 14.0 0.1 0.054 12.6 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGF98737.1 - 0.036 13.5 0.0 0.093 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 EGF98737.1 - 0.075 12.0 0.0 0.16 10.9 0.0 1.5 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 EGF98737.1 - 0.086 12.3 0.1 1.7 8.1 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.27 EGF98738.1 - 2.3e-33 112.8 12.6 4.6e-11 42.1 0.2 7.9 7 1 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 EGF98738.1 - 8.4e-17 60.9 8.3 1.4e-16 60.2 5.1 1.7 2 0 0 2 2 2 1 Sof1-like domain eIF2A PF08662.6 EGF98738.1 - 3.9e-07 29.9 0.0 1.5e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGF98738.1 - 0.032 12.3 0.8 1.2 7.2 0.0 2.7 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Herpeto_peptide PF14409.1 EGF98738.1 - 0.13 12.0 0.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Herpetosiphon LEM PF03020.10 EGF98741.1 - 0.15 11.5 0.0 0.37 10.2 0.0 1.6 1 0 0 1 1 1 0 LEM domain CFEM PF05730.6 EGF98743.1 - 5.7e-14 51.6 8.2 7.4e-14 51.3 5.7 1.1 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 EGF98743.1 - 0.79 9.7 6.4 0.098 12.6 1.5 1.7 2 0 0 2 2 2 0 Gamma-thionin family UBN2 PF14223.1 EGF98745.1 - 3.2e-05 23.7 0.0 5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGF98745.1 - 0.00012 21.6 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type VWA_2 PF13519.1 EGF98746.1 - 4e-08 33.5 0.0 6.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGF98746.1 - 7e-07 29.1 0.0 9.2e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EGF98746.1 - 2.3e-05 24.3 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Tex_N PF09371.5 EGF98746.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Tex-like protein N-terminal domain 2OG-FeII_Oxy_2 PF13532.1 EGF98748.1 - 3.7e-28 98.6 0.0 4.3e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily VWA_2 PF13519.1 EGF98749.1 - 5e-06 26.7 0.1 9.5e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGF98749.1 - 0.00039 20.1 0.0 0.00085 19.0 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EGF98749.1 - 0.014 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus DUF1183 PF06682.7 EGF98749.1 - 0.24 10.9 2.3 0.32 10.5 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF4504 PF14953.1 EGF98750.1 - 5.9e-09 35.6 0.4 8.2e-07 28.5 0.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) zf-C2H2_2 PF12756.2 EGF98751.1 - 0.11 12.6 0.1 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2894 PF11445.3 EGF98753.1 - 0.084 13.1 1.4 0.094 12.9 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF2303 PF10065.4 EGF98753.1 - 0.57 8.9 6.6 0.093 11.5 1.4 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2303) Macoilin PF09726.4 EGF98753.1 - 1.4 7.1 10.8 1.5 7.0 7.5 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1675 PF07897.6 EGF98753.1 - 7.4 6.3 12.3 8.3 6.1 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Tyrosinase PF00264.15 EGF98756.1 - 8.3e-45 153.6 0.1 1e-44 153.3 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Pyr_excise PF03013.9 EGF98756.1 - 0.14 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Sec2p PF06428.6 EGF98757.1 - 2.1e-07 30.7 6.0 2.1e-07 30.7 4.2 2.9 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p Myosin_tail_1 PF01576.14 EGF98757.1 - 0.0027 15.5 9.4 0.0052 14.5 6.5 1.4 1 0 0 1 1 1 1 Myosin tail Filament PF00038.16 EGF98757.1 - 0.0099 15.3 8.9 0.0099 15.3 6.1 2.1 3 0 0 3 3 3 1 Intermediate filament protein DUF3450 PF11932.3 EGF98757.1 - 0.014 14.6 4.4 0.035 13.3 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 EGF98757.1 - 0.024 14.2 17.6 0.37 10.3 4.8 2.4 2 0 0 2 2 2 0 IncA protein FlaC_arch PF05377.6 EGF98757.1 - 0.042 13.7 9.4 0.091 12.6 1.9 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Cortex-I_coil PF09304.5 EGF98757.1 - 0.23 11.5 16.5 0.27 11.2 7.4 3.0 3 1 0 3 3 3 0 Cortexillin I, coiled coil Med9 PF07544.8 EGF98757.1 - 0.61 9.8 7.5 0.52 10.0 2.4 2.8 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DivIVA PF05103.8 EGF98757.1 - 2.2 8.3 13.8 0.82 9.7 5.0 2.7 2 0 0 2 2 2 0 DivIVA protein V_ATPase_I PF01496.14 EGF98757.1 - 4.8 4.9 8.2 7.8 4.2 5.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF745 PF05335.8 EGF98757.1 - 5.5 6.4 7.7 1.3 8.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TBPIP PF07106.8 EGF98757.1 - 8.2 5.9 18.8 0.13 11.8 6.9 2.3 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HSBP1 PF06825.7 EGF98760.1 - 3.4e-10 39.3 0.0 4.8e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DELLA PF12041.3 EGF98760.1 - 0.1 12.2 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal DUF2934 PF11154.3 EGF98763.1 - 1.3 8.4 6.4 4.6 6.6 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) SWIB PF02201.13 EGF98764.1 - 2.9e-09 36.4 1.2 6.8e-09 35.2 0.1 2.2 2 0 0 2 2 2 1 SWIB/MDM2 domain RGS PF00615.14 EGF98765.1 - 0.042 13.9 0.1 0.081 13.0 0.1 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain Aminotran_3 PF00202.16 EGF98767.1 - 5.9e-36 123.9 0.0 5e-20 71.6 0.0 2.7 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EGF98767.1 - 3.3e-28 98.6 0.0 1.2e-27 96.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain FR47 PF08445.5 EGF98767.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Opi1 PF08618.5 EGF98769.1 - 2.3e-68 231.0 4.6 2.3e-68 231.0 3.2 3.5 2 1 0 2 2 2 1 Transcription factor Opi1 7TM_GPCR_Sri PF10327.4 EGF98769.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Proteasome PF00227.21 EGF98770.1 - 2.3e-32 111.8 0.0 4.3e-32 110.9 0.1 1.4 2 0 0 2 2 2 1 Proteasome subunit SPACA7 PF15307.1 EGF98771.1 - 0.053 13.6 8.2 0.24 11.5 2.2 2.7 2 1 0 2 2 2 0 Sperm acrosome-associated protein 7 Ribonuclease_3 PF00636.21 EGF98772.1 - 4.8e-32 110.7 0.2 5.4e-15 55.8 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGF98772.1 - 2e-22 79.4 0.1 1.4e-08 34.7 0.0 3.8 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 EGF98772.1 - 2.5e-20 72.0 0.2 3e-19 68.5 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.24 EGF98772.1 - 4.2e-18 65.4 0.0 8.6e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGF98772.1 - 1.3e-12 47.8 0.0 3.3e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGF98772.1 - 8.7e-10 38.3 0.0 2.2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 EGF98772.1 - 0.00079 19.9 0.1 0.13 12.8 0.0 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif SNF2_N PF00176.18 EGF98772.1 - 0.00087 18.1 0.1 0.0017 17.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.4 EGF98772.1 - 0.00089 18.3 0.0 0.0021 17.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EGF98772.1 - 0.047 13.8 0.0 0.16 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain DHHW PF14286.1 EGF98773.1 - 1 8.5 12.6 0.59 9.3 4.3 2.3 2 0 0 2 2 2 0 DHHW protein FKBP_C PF00254.23 EGF98774.1 - 1e-31 108.7 0.0 1.2e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF1340 PF07067.6 EGF98775.1 - 0.048 12.8 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Cofilin_ADF PF00241.15 EGF98777.1 - 1.9e-42 144.1 0.2 2.1e-42 143.9 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PP2C PF00481.16 EGF98778.1 - 1.7e-75 253.7 0.0 2.4e-75 253.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EGF98778.1 - 0.00095 18.6 0.0 0.0025 17.2 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C ABC_trans_N PF14510.1 EGF98779.1 - 0.0078 16.2 0.2 0.0078 16.2 0.1 2.2 1 1 1 2 2 2 1 ABC-transporter extracellular N-terminal DUF912 PF06024.7 EGF98779.1 - 0.14 12.1 0.9 0.29 11.2 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SieB PF14163.1 EGF98780.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B MAD PF05557.8 EGF98781.1 - 0.018 13.1 6.1 0.027 12.5 4.2 1.3 1 1 0 1 1 1 0 Mitotic checkpoint protein MFS_1 PF07690.11 EGF98783.1 - 1e-14 54.0 37.8 9.4e-07 27.8 4.8 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EGF98783.1 - 0.0023 16.3 6.2 0.0023 16.3 4.3 3.1 2 1 0 3 3 3 1 MFS/sugar transport protein Hpt PF01627.18 EGF98784.1 - 2.1e-11 43.6 0.3 3.2e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 Hpt domain CH PF00307.26 EGF98785.1 - 2.5e-39 133.6 0.1 1.7e-21 76.2 0.0 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EGF98785.1 - 4.6e-20 71.3 0.0 1.8e-19 69.4 0.0 2.1 1 1 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EGF98785.1 - 1.5e-12 46.9 0.1 2.2e-08 33.5 0.1 2.6 2 0 0 2 2 2 2 CAMSAP CH domain Spectrin PF00435.16 EGF98785.1 - 0.0047 17.1 3.5 1.7 8.9 0.4 2.8 1 1 0 2 2 2 2 Spectrin repeat Baculo_PEP_C PF04513.7 EGF98785.1 - 0.02 14.6 1.3 0.67 9.7 0.3 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_8 PF13833.1 EGF98785.1 - 0.021 14.4 0.1 0.25 10.9 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Acyl-ACP_TE PF01643.12 EGF98785.1 - 0.041 12.8 0.7 0.077 11.9 0.1 1.7 2 0 0 2 2 2 0 Acyl-ACP thioesterase Apolipoprotein PF01442.13 EGF98785.1 - 0.85 9.0 5.7 11 5.4 4.0 2.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Eaf7 PF07904.8 EGF98787.1 - 6.6e-16 58.0 0.2 2.7e-15 56.0 0.0 1.9 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 DUF2890 PF11081.3 EGF98787.1 - 0.011 15.8 1.6 0.011 15.8 1.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) RNase_Zc3h12a_2 PF14626.1 EGF98789.1 - 0.022 14.6 0.1 0.49 10.2 0.1 2.5 1 1 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain UBN2_3 PF14244.1 EGF98792.1 - 0.01 15.3 0.0 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type GRP PF07172.6 EGF98794.1 - 0.032 14.7 4.5 0.097 13.1 3.1 1.8 1 0 0 1 1 1 0 Glycine rich protein family DUF2433 PF10360.4 EGF98796.1 - 0.052 13.8 0.3 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) DUF1664 PF07889.7 EGF98796.1 - 0.063 13.0 1.8 0.13 12.0 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.7 EGF98797.1 - 0.0014 18.9 0.0 0.012 15.9 0.0 2.6 1 0 0 1 1 1 1 SlyX Motile_Sperm PF00635.21 EGF98798.1 - 2.7e-25 88.1 0.0 4.8e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain NPV_P10 PF05531.7 EGF98800.1 - 0.092 13.0 0.9 0.19 12.0 0.6 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 EGF98800.1 - 0.16 11.8 4.7 0.093 12.6 1.0 2.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EGF98800.1 - 0.37 10.3 3.7 0.68 9.4 2.6 1.4 1 0 0 1 1 1 0 IncA protein Pro_isomerase PF00160.16 EGF98802.1 - 9e-47 159.1 0.0 1.7e-46 158.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EGF98802.1 - 5.8e-07 29.1 3.5 0.14 12.1 0.1 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat SAC3_GANP PF03399.11 EGF98803.1 - 7.6e-47 159.5 0.1 9.8e-47 159.1 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family GATA PF00320.22 EGF98805.1 - 1.6 8.1 10.1 27 4.2 7.0 2.4 1 1 0 1 1 1 0 GATA zinc finger zf-CCHC_3 PF13917.1 EGF98806.1 - 1.2e-14 53.7 2.8 2.1e-14 52.9 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 EGF98806.1 - 0.0061 16.4 1.0 0.0061 16.4 0.7 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G DUF4496 PF14908.1 EGF98806.1 - 0.062 13.1 0.1 0.092 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4496) zf-CCHC PF00098.18 EGF98806.1 - 0.076 12.9 2.3 0.12 12.3 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-HIT PF04438.11 EGF98806.1 - 0.35 10.5 2.1 0.56 9.9 1.4 1.3 1 0 0 1 1 1 0 HIT zinc finger Hist_deacetyl PF00850.14 EGF98808.1 - 1.4e-52 178.9 0.1 1.9e-52 178.5 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DAGAT PF03982.8 EGF98812.1 - 1.3e-100 335.9 0.0 2e-100 335.3 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 EGF98812.1 - 1.5 8.3 12.3 5.7 6.4 7.7 2.1 1 1 1 2 2 2 0 Rer1 family Vps51 PF08700.6 EGF98813.1 - 4.7e-16 58.3 1.4 4.7e-16 58.3 1.0 2.0 2 1 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.7 EGF98813.1 - 8.6e-05 21.1 0.4 0.00011 20.7 0.2 1.2 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 EGF98813.1 - 0.0023 17.9 1.2 0.004 17.1 0.8 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Cast PF10174.4 EGF98813.1 - 0.042 11.9 0.3 0.05 11.6 0.2 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone FlgN PF05130.7 EGF98813.1 - 0.055 13.7 0.3 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 FlgN protein FadA PF09403.5 EGF98813.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Adhesion protein FadA Syntaxin-6_N PF09177.6 EGF98813.1 - 0.15 12.4 1.5 0.57 10.6 0.9 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal IncA PF04156.9 EGF98813.1 - 0.16 11.5 1.7 0.4 10.2 0.1 2.2 1 1 1 2 2 2 0 IncA protein Asp PF00026.18 EGF98814.1 - 3.2e-23 82.4 0.0 6.4e-23 81.4 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF1793 PF08760.6 EGF98815.1 - 1.4e-41 142.2 0.2 2.6e-41 141.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 EGF98815.1 - 0.033 13.3 0.1 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal Bacillus_HBL PF05791.6 EGF98816.1 - 0.019 14.3 0.4 0.031 13.6 0.3 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.1 EGF98816.1 - 0.056 12.6 2.5 0.082 12.0 1.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding XkdW PF09636.5 EGF98816.1 - 0.081 12.8 0.6 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 XkdW protein LigT_PEase PF02834.11 EGF98816.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 LigT like Phosphoesterase DUF4164 PF13747.1 EGF98816.1 - 0.13 12.4 2.4 0.22 11.6 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) CENP-F_leu_zip PF10473.4 EGF98816.1 - 0.22 11.3 7.7 0.35 10.7 5.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3402 PF11882.3 EGF98816.1 - 0.24 10.3 2.7 0.33 9.9 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) TMF_DNA_bd PF12329.3 EGF98816.1 - 0.43 10.4 4.6 9.5 6.1 0.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2365 PF10157.4 EGF98818.1 - 0.0033 17.3 4.2 0.011 15.5 0.7 3.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2365) DUF4200 PF13863.1 EGF98818.1 - 0.012 15.6 0.5 0.035 14.0 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) GAS PF13851.1 EGF98818.1 - 0.032 13.4 1.3 0.089 11.9 0.9 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EGF98818.1 - 0.036 13.5 0.2 0.086 12.3 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.7 EGF98818.1 - 0.038 14.3 0.3 0.18 12.2 0.2 2.2 1 0 0 1 1 1 0 SlyX Cep57_MT_bd PF06657.8 EGF98818.1 - 0.31 11.0 6.3 0.11 12.5 1.6 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Seryl_tRNA_N PF02403.17 EGF98818.1 - 0.54 10.3 5.9 0.18 11.8 1.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 EGF98818.1 - 1 7.9 8.3 0.022 13.4 0.6 2.0 3 0 0 3 3 3 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EGF98818.1 - 3.3 7.5 8.6 0.2 11.5 1.6 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Alpha_kinase PF02816.13 EGF98819.1 - 9.5e-22 77.5 0.3 1.8e-21 76.6 0.1 1.6 2 0 0 2 2 2 1 Alpha-kinase family FlhD PF05247.8 EGF98819.1 - 0.043 13.8 0.4 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhD) Kinase-PPPase PF03618.9 EGF98820.1 - 0.05 13.0 0.2 0.081 12.4 0.2 1.2 1 0 0 1 1 1 0 Kinase/pyrophosphorylase Prok-E2_A PF14457.1 EGF98820.1 - 0.18 11.2 6.6 1.6 8.2 0.0 2.4 1 1 1 2 2 2 0 Prokaryotic E2 family A Pkinase PF00069.20 EGF98821.1 - 8.8e-64 215.1 0.0 1e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF98821.1 - 1.1e-44 152.4 0.0 1.5e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGF98821.1 - 7.5e-06 25.1 0.0 4e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGF98821.1 - 0.049 13.3 0.1 0.95 9.1 0.1 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L29e PF01779.12 EGF98822.1 - 0.025 14.4 0.2 0.04 13.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal L29e protein family ApoLp-III PF07464.6 EGF98822.1 - 0.057 13.4 0.0 0.068 13.1 0.0 1.0 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF3439 PF11921.3 EGF98822.1 - 1.2 8.9 6.1 1.4 8.6 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4112 PF13430.1 EGF98823.1 - 7.2e-29 99.8 0.2 9.8e-29 99.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2934 PF11154.3 EGF98824.1 - 1.9 7.8 12.2 3.7 6.9 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) BPL_N PF09825.4 EGF98825.1 - 2.8e-26 92.1 0.0 2e-25 89.4 0.0 2.2 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EGF98825.1 - 4.8e-15 55.6 0.0 9.5e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Trm112p PF03966.11 EGF98826.1 - 3.5e-16 59.3 0.0 5.8e-16 58.6 0.0 1.4 1 1 0 1 1 1 1 Trm112p-like protein zf-NADH-PPase PF09297.6 EGF98826.1 - 0.092 12.2 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain FNIP PF05725.7 EGF98826.1 - 0.4 10.6 5.7 0.22 11.5 0.5 2.7 2 1 1 3 3 3 0 FNIP Repeat K_oxygenase PF13434.1 EGF98827.1 - 3.4e-86 289.2 0.0 8.6e-56 189.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGF98827.1 - 1.1e-06 28.4 0.0 7.8e-05 22.4 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EGF98827.1 - 0.058 13.4 0.0 1.1 9.2 0.0 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IcmF-related PF06761.7 EGF98828.1 - 0.033 13.5 0.0 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 Intracellular multiplication and human macrophage-killing Vezatin PF12632.2 EGF98828.1 - 0.037 13.0 0.1 0.07 12.2 0.1 1.4 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes TMA7 PF09072.5 EGF98830.1 - 0.048 14.1 0.3 0.083 13.3 0.2 1.3 1 0 0 1 1 1 0 Translation machinery associated TMA7 FAR1 PF03101.10 EGF98831.1 - 0.00013 22.4 1.3 0.00031 21.1 0.9 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EGF98831.1 - 0.036 14.2 6.3 0.084 13.0 4.4 1.9 1 1 0 1 1 1 0 Transcription factor AFT Baculo_PEP_C PF04513.7 EGF98834.1 - 0.01 15.6 1.8 0.017 14.9 1.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRF_GI PF12614.3 EGF98834.1 - 0.074 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosome recycling factor LPP PF04728.8 EGF98834.1 - 1.5 8.6 3.7 2.1 8.1 1.5 2.0 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Alpha_kinase PF02816.13 EGF98836.1 - 2.8e-05 23.8 0.0 0.00062 19.4 0.0 2.1 1 1 1 2 2 2 2 Alpha-kinase family TFIIA PF03153.8 EGF98837.1 - 0.035 13.9 25.0 0.083 12.7 17.3 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PT PF04886.7 EGF98837.1 - 0.79 9.0 16.0 1.5 8.1 11.1 1.5 1 0 0 1 1 1 0 PT repeat SDA1 PF05285.7 EGF98837.1 - 0.93 8.7 19.2 2 7.5 13.3 1.6 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 EGF98837.1 - 1.5 6.7 10.9 2.1 6.2 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 EGF98837.1 - 3.6 5.5 16.0 5.4 5.0 11.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AlphaC_N PF08829.5 EGF98838.1 - 0.11 11.8 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Alpha C protein N terminal DUF3446 PF11928.3 EGF98839.1 - 0.51 10.5 5.7 0.11 12.7 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) MFS_1 PF07690.11 EGF98841.1 - 1.7e-11 43.4 7.2 1.9e-11 43.2 5.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.14 EGF98841.1 - 0.00037 19.1 1.8 0.00043 18.9 0.4 1.7 1 1 0 2 2 2 1 LacY proton/sugar symporter UPF0104 PF03706.8 EGF98841.1 - 0.0047 16.2 4.4 0.0062 15.8 3.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) DUF3317 PF11779.3 EGF98841.1 - 0.02 14.3 2.4 0.058 12.8 1.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) DUF1469 PF07332.6 EGF98841.1 - 0.28 10.9 1.5 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) ABC2_membrane_5 PF13346.1 EGF98841.1 - 8.3 5.6 13.6 0.43 9.8 3.0 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein TFIIA PF03153.8 EGF98842.1 - 0.66 9.8 28.7 0.76 9.6 9.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.7 EGF98842.1 - 2.3 7.2 21.0 3.7 6.5 14.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ubiquitin PF00240.18 EGF98844.1 - 6.2e-35 118.4 0.5 7.7e-35 118.1 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGF98844.1 - 1.2e-19 69.7 0.6 1.5e-19 69.4 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L40e PF01020.12 EGF98844.1 - 1e-07 31.4 0.9 1.9e-07 30.5 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Ubiquitin_2 PF14560.1 EGF98844.1 - 1.1e-05 25.6 0.1 3.8e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGF98844.1 - 0.0014 18.3 0.0 0.0019 17.9 0.0 1.1 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EGF98844.1 - 0.0073 16.1 0.0 0.014 15.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGF98844.1 - 0.017 15.2 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF89 PF01937.14 EGF98846.1 - 4.6e-30 104.5 0.0 5.2e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Cullin PF00888.17 EGF98847.1 - 1.4e-16 60.2 0.3 6.6e-12 44.7 0.1 2.8 2 1 1 3 3 3 2 Cullin family APC2 PF08672.6 EGF98847.1 - 1.7e-06 28.1 0.0 4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 adh_short_C2 PF13561.1 EGF98850.1 - 1.4e-05 25.0 0.0 2.6e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Helicase_C PF00271.26 EGF98851.1 - 2.1e-06 27.5 0.0 5.3e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNase_H2-Ydr279 PF09468.5 EGF98851.1 - 0.14 11.3 9.8 0.24 10.5 6.8 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Abhydrolase_6 PF12697.2 EGF98855.1 - 2.5e-25 89.7 0.0 3.3e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGF98855.1 - 4.7e-12 45.9 0.0 1.4e-11 44.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGF98855.1 - 4e-09 36.3 0.0 8.8e-09 35.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGF98855.1 - 0.00014 22.1 0.1 0.00028 21.1 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 EGF98855.1 - 0.00065 19.5 0.1 0.002 17.9 0.1 1.8 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 EGF98855.1 - 0.0018 17.9 0.1 0.0032 17.1 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 EGF98855.1 - 0.0049 16.3 0.0 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) VirJ PF06057.6 EGF98855.1 - 0.022 14.5 0.0 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 EGF98855.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.7 EGF98855.1 - 0.098 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.8 EGF98855.1 - 0.21 11.1 1.6 0.75 9.3 1.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Syja_N PF02383.13 EGF98857.1 - 2.2e-64 217.2 0.1 9.1e-64 215.2 0.1 1.7 1 1 0 1 1 1 1 SacI homology domain Oxysterol_BP PF01237.13 EGF98858.1 - 4.2e-21 74.8 0.0 5e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Seryl_tRNA_N PF02403.17 EGF98859.1 - 0.46 10.5 15.5 0.45 10.5 8.5 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-CCHC_4 PF14392.1 EGF98861.1 - 0.1 12.2 0.9 0.21 11.2 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle NOA36 PF06524.7 EGF98863.1 - 0.059 12.6 0.1 0.071 12.3 0.0 1.0 1 0 0 1 1 1 0 NOA36 protein Nro1 PF12753.2 EGF98866.1 - 0.46 9.3 5.2 0.18 10.7 2.0 1.4 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 Pox_Ag35 PF03286.9 EGF98866.1 - 0.55 9.7 4.9 0.43 10.0 2.5 1.4 1 1 0 1 1 1 0 Pox virus Ag35 surface protein TT_ORF2 PF02957.10 EGF98866.1 - 0.64 10.7 5.9 0.14 12.9 1.9 1.6 2 0 0 2 2 2 0 TT viral ORF2 DUF384 PF04064.8 EGF98870.1 - 0.013 15.0 0.0 30 4.2 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF384) Catalase PF00199.14 EGF98872.1 - 2.9e-159 529.8 0.2 3.8e-159 529.4 0.1 1.2 1 0 0 1 1 1 1 Catalase Ras PF00071.17 EGF98873.1 - 1.9e-52 176.9 0.0 2.1e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGF98873.1 - 3.9e-19 69.2 0.0 4.9e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGF98873.1 - 3.2e-09 36.2 0.0 3.4e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGF98873.1 - 8.3e-06 25.3 0.0 0.00028 20.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGF98873.1 - 2.6e-05 24.1 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGF98873.1 - 0.00021 20.6 0.1 0.0016 17.7 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_25 PF13481.1 EGF98873.1 - 0.014 14.7 0.1 0.03 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGF98873.1 - 0.024 13.8 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EGF98873.1 - 0.034 13.7 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EGF98873.1 - 0.036 13.0 0.0 0.073 12.0 0.0 1.5 2 0 0 2 2 2 0 Septin CbiA PF01656.18 EGF98873.1 - 0.052 12.9 0.1 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Gtr1_RagA PF04670.7 EGF98873.1 - 0.054 12.6 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGF98873.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DAP3 PF10236.4 EGF98873.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.5 EGF98873.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FEZ PF07763.8 EGF98874.1 - 0.15 11.7 9.9 0.18 11.4 1.6 2.7 2 1 1 3 3 3 0 FEZ-like protein PH PF00169.24 EGF98875.1 - 1.8e-15 57.0 0.0 4.8e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 EGF98875.1 - 6.5e-14 51.2 0.1 1.2e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGF98875.1 - 2.6e-13 49.1 0.4 5.7e-13 48.0 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGF98875.1 - 1.3e-09 37.3 0.0 2.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 EGF98875.1 - 4.4e-08 32.8 0.0 1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CH PF00307.26 EGF98875.1 - 4.6e-06 26.6 0.0 1.6e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain PH_11 PF15413.1 EGF98875.1 - 1.6e-05 25.1 0.1 5.5e-05 23.3 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.25 EGF98875.1 - 0.00011 22.3 0.1 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_9 PF15410.1 EGF98875.1 - 0.077 13.1 0.1 4.6 7.4 0.1 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain Ste50p-SAM PF09235.5 EGF98875.1 - 0.11 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Ground-like PF04155.13 EGF98875.1 - 0.26 11.6 0.0 0.7 10.2 0.0 1.6 1 0 0 1 1 1 0 Ground-like domain ABC2_membrane PF01061.19 EGF98878.1 - 3.1e-79 265.0 60.6 7.4e-42 142.9 19.1 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EGF98878.1 - 4.3e-34 116.2 1.0 2.8e-24 84.7 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EGF98878.1 - 2.5e-31 108.7 0.0 2.7e-14 53.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 EGF98878.1 - 0.00021 20.7 0.4 0.011 15.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EGF98878.1 - 0.00023 20.3 40.7 0.0009 18.3 11.5 3.1 2 1 0 3 3 2 2 ABC-2 family transporter protein AAA_10 PF12846.2 EGF98878.1 - 0.0003 20.3 0.1 0.021 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 EGF98878.1 - 0.00031 19.9 0.0 0.00056 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGF98878.1 - 0.0014 18.1 0.3 0.014 14.9 0.3 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGF98878.1 - 0.0023 17.8 0.0 0.93 9.4 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.1 EGF98878.1 - 0.0049 16.8 0.2 0.67 9.8 0.2 2.6 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.1 EGF98878.1 - 0.0066 16.5 0.0 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal SMC_N PF02463.14 EGF98878.1 - 0.007 15.6 0.0 0.29 10.3 0.0 3.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EGF98878.1 - 0.014 15.2 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGF98878.1 - 0.018 15.2 0.0 0.095 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGF98878.1 - 0.018 15.0 0.1 0.06 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 EGF98878.1 - 0.03 13.7 1.0 0.053 12.9 0.7 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EGF98878.1 - 0.035 14.0 0.1 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGF98878.1 - 0.089 12.4 0.0 6.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_15 PF13175.1 EGF98878.1 - 0.093 11.7 0.0 0.58 9.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 EGF98878.1 - 0.82 9.1 1.7 1.2 8.5 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane PF01061.19 EGF98880.1 - 5.1e-81 270.8 67.2 6e-42 143.1 21.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EGF98880.1 - 2e-34 117.3 2.4 2.8e-25 87.9 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EGF98880.1 - 7.9e-31 107.1 0.0 2.1e-14 53.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 EGF98880.1 - 4.4e-05 22.9 0.2 0.0073 15.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EGF98880.1 - 0.00012 21.1 54.6 0.00054 19.1 12.6 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_10 PF12846.2 EGF98880.1 - 0.00052 19.5 0.1 0.041 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 EGF98880.1 - 0.00068 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGF98880.1 - 0.0013 18.1 0.2 0.013 15.0 0.3 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EGF98880.1 - 0.005 16.8 0.2 0.65 9.9 0.2 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGF98880.1 - 0.0054 16.6 0.0 2.2 8.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGF98880.1 - 0.0099 16.0 0.0 0.091 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EGF98880.1 - 0.019 14.2 0.0 1.9 7.6 0.0 3.0 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EGF98880.1 - 0.019 14.8 0.0 0.062 13.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.1 EGF98880.1 - 0.027 14.4 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 EGF98880.1 - 0.029 13.8 1.0 0.051 13.0 0.7 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EGF98880.1 - 0.032 14.1 0.1 0.077 12.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGF98880.1 - 0.061 13.0 0.1 7.3 6.2 0.1 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_15 PF13175.1 EGF98880.1 - 0.069 12.1 0.0 0.43 9.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EGF98880.1 - 0.22 12.3 0.0 1.1 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain HTH_Tnp_Tc3_2 PF01498.13 EGF98881.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Transposase SH3_2 PF07653.12 EGF98882.1 - 0.049 13.1 0.8 0.26 10.8 0.0 2.5 3 0 0 3 3 3 0 Variant SH3 domain ABC2_membrane PF01061.19 EGF98883.1 - 1e-80 269.8 65.5 5.7e-42 143.2 19.5 2.9 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EGF98883.1 - 3.9e-34 116.4 1.3 6.6e-25 86.7 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EGF98883.1 - 9.6e-30 103.6 0.0 4.6e-14 52.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EGF98883.1 - 1.4e-07 30.9 37.0 9.2e-06 24.9 3.9 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EGF98883.1 - 9.2e-07 28.8 0.0 2.4e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EGF98883.1 - 5.2e-05 22.7 0.2 0.0077 15.6 0.1 2.8 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EGF98883.1 - 0.00075 18.7 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGF98883.1 - 0.0016 17.9 0.2 0.014 14.8 0.3 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EGF98883.1 - 0.0019 17.6 0.2 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_21 PF13304.1 EGF98883.1 - 0.0031 17.5 0.3 0.72 9.7 0.2 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGF98883.1 - 0.006 16.5 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.14 EGF98883.1 - 0.014 14.6 0.0 1.1 8.3 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EGF98883.1 - 0.015 15.4 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGF98883.1 - 0.017 15.1 0.0 0.05 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EGF98883.1 - 0.022 14.6 0.0 0.078 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EGF98883.1 - 0.029 13.8 1.0 0.056 12.8 0.7 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EGF98883.1 - 0.033 14.1 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EGF98883.1 - 0.069 12.1 0.0 0.66 8.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 EGF98883.1 - 0.076 12.6 0.1 8 6.0 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 EGF98883.1 - 0.16 12.8 0.3 1.5 9.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain CoA_binding PF02629.14 EGF98884.1 - 7.1e-29 100.1 0.6 1.5e-28 99.1 0.1 1.8 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EGF98884.1 - 1.7e-25 89.4 0.1 2.7e-25 88.7 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EGF98884.1 - 1.7e-07 30.9 0.1 3.9e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EGF98884.1 - 5.4e-06 26.5 0.1 2.1e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 EGF98884.1 - 0.00039 20.9 0.0 0.001 19.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DCP2 PF05026.8 EGF98885.1 - 3e-26 91.1 0.2 5.1e-26 90.3 0.2 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EGF98885.1 - 6.5e-18 64.6 0.0 1e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Sugar_tr PF00083.19 EGF98887.1 - 2.7e-107 359.1 28.9 3.2e-107 358.9 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGF98887.1 - 9.7e-23 80.4 60.7 2.7e-19 69.1 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGF98887.1 - 0.00088 17.4 4.1 0.0051 14.9 0.5 2.5 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family CLN3 PF02487.12 EGF98888.1 - 1.6e-66 224.8 18.2 4.2e-64 216.7 12.6 2.0 1 1 0 1 1 1 1 CLN3 protein Aldose_epim PF01263.15 EGF98892.1 - 3.5e-27 95.2 0.0 5.5e-27 94.6 0.0 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase DUF4432 PF14486.1 EGF98892.1 - 0.025 13.1 0.0 0.045 12.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4432) DUF22 PF01629.11 EGF98892.1 - 0.047 13.1 0.1 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF22 Sgf11 PF08209.6 EGF98893.1 - 7.1e-06 25.2 0.2 1.1e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Orthopox_A36R PF05950.6 EGF98893.1 - 0.034 14.0 1.3 0.034 14.0 0.9 1.5 2 0 0 2 2 2 0 Orthopoxvirus A36R protein Endosulfine PF04667.12 EGF98893.1 - 0.041 13.8 1.6 0.26 11.2 0.0 2.8 2 1 0 2 2 2 0 cAMP-regulated phosphoprotein/endosulfine conserved region Presenilin PF01080.12 EGF98893.1 - 3.9 6.2 4.1 5.1 5.8 2.8 1.1 1 0 0 1 1 1 0 Presenilin MTBP_C PF14920.1 EGF98893.1 - 4.9 6.5 9.9 3.4 7.1 5.9 1.4 1 1 0 1 1 1 0 MDM2-binding Nop14 PF04147.7 EGF98894.1 - 0.019 12.9 3.0 0.022 12.6 2.1 1.0 1 0 0 1 1 1 0 Nop14-like family ELH PF02323.10 EGF98894.1 - 1.3 8.1 4.6 2.2 7.3 0.3 2.1 1 1 1 2 2 2 0 Egg-laying hormone precursor Erv26 PF04148.8 EGF98897.1 - 2e-58 197.2 14.6 2.3e-58 197.0 10.1 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 MnhB PF04039.8 EGF98897.1 - 0.039 14.0 0.9 0.039 14.0 0.6 1.9 1 1 2 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter NYAP_C PF15452.1 EGF98898.1 - 0.0035 16.4 0.1 0.0041 16.1 0.1 1.1 1 0 0 1 1 1 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter zf-like PF04071.7 EGF98898.1 - 1.7 8.3 7.4 4 7.1 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich small domain Ribosomal_L10 PF00466.15 EGF98900.1 - 9e-19 67.2 0.0 1.9e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 DUF4078 PF13300.1 EGF98902.1 - 1.5e-08 34.6 3.7 3.7e-08 33.3 2.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4078) PhnA_Zn_Ribbon PF08274.7 EGF98903.1 - 0.062 13.1 1.1 0.94 9.3 0.0 2.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.1 EGF98903.1 - 0.72 9.1 4.8 2.8 7.2 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EGF98903.1 - 1 8.9 5.5 3.4 7.2 0.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 EGF98903.1 - 2.2 8.1 10.5 1.9 8.3 5.7 2.0 1 1 1 2 2 2 0 Double zinc ribbon RRXRR PF14239.1 EGF98904.1 - 0.094 12.1 2.4 0.11 11.9 1.7 1.1 1 0 0 1 1 1 0 RRXRR protein SspP PF08179.7 EGF98904.1 - 0.43 10.7 3.2 0.5 10.6 0.1 2.1 2 0 0 2 2 2 0 Small acid-soluble spore protein P family HORMA PF02301.13 EGF98905.1 - 1.4e-25 90.0 0.1 1.6e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EGF98905.1 - 0.0022 17.4 0.1 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 13 O-FucT PF10250.4 EGF98906.1 - 1.3e-05 24.4 0.0 0.027 13.5 0.0 2.1 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Phage_1_1 PF08200.6 EGF98906.1 - 0.015 15.4 0.3 0.05 13.8 0.2 1.9 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein Pox_A_type_inc PF04508.7 EGF98907.1 - 0.2 11.4 1.4 1.1 9.2 0.3 2.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Lebercilin PF15619.1 EGF98907.1 - 3.3 7.1 8.1 15 4.9 0.2 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Prefoldin_2 PF01920.15 EGF98907.1 - 4.9 6.9 5.9 12 5.7 0.0 3.0 3 0 0 3 3 3 0 Prefoldin subunit HEAT_2 PF13646.1 EGF98908.1 - 1.1e-36 124.9 7.8 6.8e-17 61.5 0.1 3.2 2 1 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.11 EGF98908.1 - 5.4e-22 75.9 0.9 0.0015 18.8 0.0 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EGF98908.1 - 5.4e-10 39.4 4.2 0.0026 18.2 0.0 5.4 4 2 1 5 5 5 3 HEAT-like repeat HEAT PF02985.17 EGF98908.1 - 4.8e-09 35.5 3.0 0.1 12.7 0.0 5.3 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.18 EGF98908.1 - 2.5e-05 23.9 0.1 0.012 15.4 0.0 3.7 2 1 1 3 3 3 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EGF98909.1 - 3.9e-18 65.0 0.2 4.1e-18 64.9 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EGF98909.1 - 4.1e-07 29.5 0.1 0.00056 19.7 0.0 2.4 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.1 EGF98909.1 - 4e-05 23.8 0.0 6.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 HEAT repeats Adaptin_N PF01602.15 EGF98910.1 - 2.3e-18 65.8 0.2 2.7e-18 65.6 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Sugar_tr PF00083.19 EGF98912.1 - 4.1e-108 361.8 28.3 4.7e-108 361.6 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGF98912.1 - 3.5e-22 78.5 34.4 6e-15 54.8 3.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 EGF98912.1 - 0.029 14.3 1.6 0.18 11.8 1.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) DUF697 PF05128.7 EGF98912.1 - 0.098 12.1 1.2 0.31 10.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF697) DUF3661 PF12400.3 EGF98913.1 - 8.3e-27 93.8 3.0 1.2e-26 93.3 2.1 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein GATase_4 PF13230.1 EGF98915.1 - 0.0017 17.0 0.1 0.0022 16.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II FCP1_C PF09309.5 EGF98915.1 - 0.041 13.1 1.7 0.045 13.0 1.2 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF3498 PF12004.3 EGF98915.1 - 2.2 7.3 6.6 2.9 6.9 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Peptidase_C48 PF02902.14 EGF98916.1 - 2.8e-05 23.8 0.1 0.00011 21.9 0.1 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF605 PF04652.11 EGF98916.1 - 0.064 12.6 19.1 0.082 12.2 13.3 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EGF98916.1 - 0.38 8.9 12.3 0.45 8.6 8.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DNA_pol_A_exo1 PF01612.15 EGF98920.1 - 0.1 12.0 0.2 10 5.5 0.1 2.5 1 1 1 2 2 2 0 3'-5' exonuclease Spore_coat_CotO PF14153.1 EGF98921.1 - 0.31 10.4 8.2 0.4 10.0 5.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO zf-CCHC PF00098.18 EGF98924.1 - 0.25 11.3 2.2 0.37 10.8 1.5 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGF98924.1 - 0.31 10.7 1.6 0.67 9.6 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle WD40 PF00400.27 EGF98925.1 - 1.7e-08 34.0 12.6 0.00097 18.9 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Lactamase_B_2 PF12706.2 EGF98926.1 - 2.1e-11 43.7 0.5 2.4e-11 43.5 0.4 1.0 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGF98926.1 - 0.004 16.8 1.1 0.007 16.0 0.7 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EGF98926.1 - 0.0091 15.7 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.10 EGF98926.1 - 0.022 13.7 0.3 0.99 8.2 0.5 2.0 1 1 1 2 2 2 0 cAMP phosphodiesterases class-II LIM_bind PF01803.11 EGF98927.1 - 6.1e-26 90.9 0.1 1.6e-18 66.7 0.0 10.8 6 4 5 11 11 11 2 LIM-domain binding protein Caldesmon PF02029.10 EGF98927.1 - 0.00019 20.0 5.4 0.00019 20.0 3.7 4.0 4 0 0 4 4 4 1 Caldesmon PIP5K PF01504.13 EGF98928.1 - 1.2e-42 145.8 0.2 2.4e-42 144.8 0.1 1.5 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MFS_1 PF07690.11 EGF98932.1 - 1.6e-17 63.2 14.2 4e-16 58.6 9.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGF98932.1 - 7.1e-13 47.9 6.1 7.1e-13 47.9 4.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Ank_2 PF12796.2 EGF98934.1 - 7.2e-21 74.3 0.2 3.8e-09 36.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGF98934.1 - 2.3e-18 64.9 0.7 4.1e-08 32.6 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EGF98934.1 - 1.8e-16 58.5 0.5 7.4e-05 22.6 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EGF98934.1 - 1.5e-14 54.0 0.8 1e-06 29.0 0.1 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGF98934.1 - 3.5e-13 49.3 0.6 1.1e-05 25.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EGF98934.1 - 1e-05 25.1 0.1 0.00013 21.5 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain DUF724 PF05266.9 EGF98935.1 - 0.043 13.4 0.5 0.077 12.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TFIIA PF03153.8 EGF98935.1 - 0.76 9.6 23.5 1.3 8.8 16.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HMGL-like PF00682.14 EGF98936.1 - 2.6e-41 141.8 0.0 5.6e-41 140.7 0.0 1.5 1 1 0 1 1 1 1 HMGL-like CRAL_TRIO PF00650.15 EGF98938.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 CRAL/TRIO domain Kinetochor_Ybp2 PF08568.5 EGF98940.1 - 0.0046 15.2 1.4 0.028 12.6 0.1 2.0 1 1 1 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Ost4 PF10215.4 EGF98942.1 - 4.6e-08 32.4 0.3 6.4e-08 31.9 0.2 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase ODV-E18 PF10717.4 EGF98942.1 - 0.042 13.2 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF912 PF06024.7 EGF98942.1 - 0.11 12.5 0.1 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) GPI-anchored PF10342.4 EGF98943.1 - 0.00044 20.6 0.0 0.0054 17.1 0.0 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Wzt_C PF14524.1 EGF98943.1 - 0.0052 16.4 0.0 1.6 8.4 0.0 3.4 3 1 0 3 3 3 1 Wzt C-terminal domain DUF4469 PF14734.1 EGF98943.1 - 0.0068 16.2 0.0 2.9 7.8 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4469) with IG-like fold A2M_N PF01835.14 EGF98943.1 - 0.01 16.0 0.1 6.8 7.0 0.0 3.3 3 0 0 3 3 3 0 MG2 domain Sec63 PF02889.11 EGF98944.1 - 2.5e-26 92.6 0.0 4.2e-26 91.9 0.0 1.3 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EGF98944.1 - 6.4e-17 61.0 0.1 1.8e-16 59.6 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain COX17 PF05051.8 EGF98945.1 - 3.5e-18 65.3 1.5 4.7e-18 64.9 1.1 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CRAL_TRIO_N PF03765.10 EGF98946.1 - 1.9e-07 31.0 0.3 5.5e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Kinesin PF00225.18 EGF98947.1 - 3.1e-90 302.2 0.0 4.2e-90 301.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Tektin PF03148.9 EGF98947.1 - 0.025 13.1 4.7 0.044 12.3 3.2 1.3 1 0 0 1 1 1 0 Tektin family Spc7 PF08317.6 EGF98947.1 - 0.14 10.7 5.6 0.23 10.0 3.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein RabGAP-TBC PF00566.13 EGF98950.1 - 9.3e-12 44.8 1.3 1.2e-11 44.5 0.9 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LIX1 PF14954.1 EGF98950.1 - 0.011 14.7 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 0 Limb expression 1 MSG PF02349.10 EGF98952.1 - 2.7 8.0 10.3 6.8 6.7 7.2 1.7 1 1 0 1 1 1 0 Major surface glycoprotein DUF2667 PF10868.3 EGF98952.1 - 6.8 7.1 8.8 79 3.7 6.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2667) DUF1515 PF07439.6 EGF98953.1 - 0.064 13.0 0.2 0.17 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Msg2_C PF12373.3 EGF98953.1 - 0.08 12.1 0.1 0.19 10.9 0.1 1.6 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal OmpH PF03938.9 EGF98953.1 - 0.33 10.8 3.9 0.093 12.6 0.6 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FYVE_2 PF02318.11 EGF98958.1 - 0.35 10.7 2.8 0.46 10.4 1.9 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger F-box-like PF12937.2 EGF98963.1 - 0.00053 19.6 0.3 0.0022 17.6 0.2 2.1 1 1 0 1 1 1 1 F-box-like DUF3716 PF12511.3 EGF98964.1 - 2 8.1 9.5 0.86 9.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3716) Alpha_kinase PF02816.13 EGF98966.1 - 5.1e-05 23.0 0.1 6.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Adhes-Ig_like PF09085.5 EGF98966.1 - 0.064 13.1 0.1 0.13 12.1 0.0 1.5 2 0 0 2 2 2 0 Adhesion molecule, immunoglobulin-like CDC27 PF09507.5 EGF98967.1 - 3.4 6.7 10.9 4.6 6.3 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AKAP2_C PF15304.1 EGF98967.1 - 6.2 6.3 7.6 8 5.9 5.2 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus FliJ PF02050.11 EGF98969.1 - 0.006 16.6 0.7 0.012 15.7 0.5 1.5 1 0 0 1 1 1 1 Flagellar FliJ protein CENP-F_leu_zip PF10473.4 EGF98969.1 - 0.2 11.5 10.3 0.12 12.1 4.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 EGF98969.1 - 0.38 11.0 4.3 0.48 10.7 0.9 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cep57_CLD_2 PF14197.1 EGF98969.1 - 0.83 9.6 7.4 0.69 9.9 2.5 2.5 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Ras PF00071.17 EGF98973.1 - 9.9e-58 194.0 0.1 1.2e-57 193.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGF98973.1 - 2.9e-20 72.9 0.0 4.5e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGF98973.1 - 6.9e-09 35.1 0.0 8.4e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGF98973.1 - 1.1e-06 28.2 0.0 2.3e-06 27.1 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGF98973.1 - 0.005 16.7 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGF98973.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EGF98973.1 - 0.052 12.6 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ser_hydrolase PF06821.8 EGF98973.1 - 0.081 12.5 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase DUF258 PF03193.11 EGF98973.1 - 0.11 11.7 0.1 0.25 10.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EGF98973.1 - 0.17 11.3 1.6 1.4 8.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PFK PF00365.15 EGF98974.1 - 1.6e-158 526.0 2.2 3.2e-93 311.7 0.6 3.1 3 0 0 3 3 3 3 Phosphofructokinase TgMIC1 PF11476.3 EGF98974.1 - 0.023 14.2 0.1 8.4 5.9 0.0 2.7 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Sod_Cu PF00080.15 EGF98975.1 - 1.6e-18 67.1 0.0 2.8e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.7 EGF98975.1 - 0.17 12.4 2.9 0.34 11.5 0.5 2.4 2 1 0 2 2 2 0 CHRD domain Proteasome PF00227.21 EGF98976.1 - 2.8e-46 157.2 0.0 3.6e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGF98976.1 - 8e-15 53.8 0.2 1.4e-14 53.1 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SurE PF01975.12 EGF98977.1 - 9.9e-31 106.5 0.1 1.2e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE RRM_5 PF13893.1 EGF98978.1 - 9.8e-05 22.1 0.0 0.0012 18.5 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGF98978.1 - 0.00039 20.3 0.0 0.0028 17.6 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGF98978.1 - 0.012 15.2 0.0 0.27 10.9 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 5_3_exonuc PF01367.15 EGF98978.1 - 0.013 15.7 0.0 0.038 14.2 0.0 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold zf-UBP PF02148.14 EGF98979.1 - 0.054 13.6 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein SF-assemblin PF06705.6 EGF98980.1 - 0.023 13.8 0.8 0.023 13.8 0.5 1.6 2 0 0 2 2 2 0 SF-assemblin/beta giardin Apolipoprotein PF01442.13 EGF98980.1 - 0.048 13.1 1.4 0.14 11.6 0.2 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 EGF98980.1 - 0.12 12.2 2.1 0.29 10.9 1.5 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 EGF98980.1 - 0.18 12.2 4.5 0.51 10.7 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) LRR_4 PF12799.2 EGF98981.1 - 1.2e-42 142.9 40.4 8.9e-09 34.7 1.2 7.4 3 2 3 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGF98981.1 - 1.6e-22 79.0 36.9 3.4e-07 29.9 0.8 6.7 3 3 2 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 EGF98981.1 - 8.8e-17 58.5 31.5 0.042 13.8 0.0 11.8 12 0 0 12 12 12 7 Leucine Rich Repeat LRR_6 PF13516.1 EGF98981.1 - 2.7e-15 54.6 31.7 0.04 13.9 0.1 11.1 4 2 6 10 10 10 5 Leucine Rich repeat LRR_9 PF14580.1 EGF98981.1 - 1.8e-13 50.4 12.8 2.8e-05 23.7 0.9 3.6 2 1 2 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 EGF98981.1 - 9.3e-12 43.1 27.7 0.37 11.1 0.0 11.1 12 0 0 12 12 12 5 Leucine rich repeat GrpE PF01025.14 EGF98982.1 - 0.073 12.6 0.5 0.98 8.9 0.0 2.7 3 0 0 3 3 3 0 GrpE DUF4559 PF15112.1 EGF98984.1 - 0.027 13.6 0.1 2.7 7.0 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4559) F420_ligase PF01996.11 EGF98987.1 - 0.034 13.2 0.4 0.064 12.3 0.0 1.6 2 0 0 2 2 2 0 F420-0:Gamma-glutamyl ligase DUF1675 PF07897.6 EGF98987.1 - 0.15 11.8 5.8 0.21 11.4 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) NDUF_B7 PF05676.8 EGF98988.1 - 1.5e-31 107.5 4.1 2e-31 107.2 2.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EGF98988.1 - 0.0029 17.3 3.8 0.0035 17.0 2.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Rsa3 PF14615.1 EGF98989.1 - 0.007 15.6 0.3 0.024 13.9 0.0 2.1 2 1 0 2 2 2 1 Ribosome-assembly protein 3 SR-25 PF10500.4 EGF98989.1 - 0.0099 15.3 8.9 0.015 14.8 6.2 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF305 PF03713.8 EGF98989.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF305) Macoilin PF09726.4 EGF98989.1 - 0.13 10.4 1.9 0.14 10.4 1.3 1.1 1 0 0 1 1 1 0 Transmembrane protein mRNA_cap_enzyme PF01331.14 EGF98994.1 - 1.1e-46 158.9 0.0 1.8e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EGF98994.1 - 3.9e-15 56.0 0.3 8.4e-15 54.9 0.2 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EGF98994.1 - 9e-08 31.7 0.0 2.2e-05 23.8 0.0 3.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Alpha_kinase PF02816.13 EGF98995.1 - 1.1e-06 28.4 0.2 2e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family ORC6 PF05460.8 EGF98997.1 - 0.13 11.3 7.0 0.18 10.8 4.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NUP50 PF08911.6 EGF98998.1 - 5.4 7.4 7.6 0.69 10.3 0.9 2.2 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) AnfO_nitrog PF09582.5 EGF98999.1 - 0.05 12.7 0.2 0.57 9.2 0.1 2.2 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DUF1515 PF07439.6 EGF98999.1 - 0.69 9.7 6.8 0.76 9.6 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) YlqD PF11068.3 EGF98999.1 - 0.95 9.4 7.3 0.46 10.5 3.0 2.0 2 1 0 2 2 2 0 YlqD protein DUF4313 PF14190.1 EGF99000.1 - 0.042 13.5 0.9 0.098 12.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4313) PhaP_Bmeg PF09602.5 EGF99000.1 - 0.1 12.3 13.9 0.18 11.5 2.0 2.5 1 1 2 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF445 PF04286.7 EGF99000.1 - 0.42 10.0 15.9 0.71 9.3 11.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) IL6 PF00489.12 EGF99000.1 - 0.71 9.4 11.5 0.14 11.7 2.8 2.5 2 1 1 3 3 3 0 Interleukin-6/G-CSF/MGF family FliE PF02049.13 EGF99000.1 - 1.1 9.3 6.8 1.1 9.3 2.2 2.8 2 2 1 3 3 3 0 Flagellar hook-basal body complex protein FliE Vip3A_N PF12495.3 EGF99000.1 - 1.5 8.4 11.5 0.056 13.1 1.2 2.6 1 1 2 3 3 3 0 Vegetative insecticide protein 3A N terminal Bac_small_YrzI PF09501.5 EGF99000.1 - 3.8 7.4 7.2 3.2 7.7 0.5 3.0 1 1 2 3 3 3 0 Probable sporulation protein (Bac_small_yrzI) DDT PF02791.12 EGF99000.1 - 5.8 6.7 6.7 1.9 8.3 0.2 3.1 2 1 0 2 2 2 0 DDT domain Glutaredoxin PF00462.19 EGF99001.1 - 3.4e-17 62.1 0.2 4.7e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.1 EGF99001.1 - 0.00014 21.4 0.1 0.00015 21.3 0.1 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.1 EGF99001.1 - 0.00059 20.0 0.9 0.0012 19.0 0.6 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EGF99001.1 - 0.0018 18.0 0.1 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.1 EGF99001.1 - 0.0031 17.5 0.1 0.0075 16.2 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like DUF836 PF05768.9 EGF99001.1 - 0.0049 17.1 0.2 0.0076 16.4 0.2 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.1 EGF99001.1 - 0.027 14.4 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 EGF99001.1 - 0.029 13.9 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin GST_N_3 PF13417.1 EGF99001.1 - 0.054 13.7 0.0 0.068 13.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MtrA PF04208.9 EGF99001.1 - 0.055 12.9 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A Thioredoxin PF00085.15 EGF99001.1 - 0.1 12.2 0.1 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.1 EGF99001.1 - 0.13 12.3 0.2 0.19 11.8 0.2 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.1 EGF99001.1 - 0.17 11.9 1.4 2 8.4 0.3 2.0 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.19 EGF99002.1 - 4.9e-18 64.8 0.1 7e-18 64.3 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EGF99002.1 - 0.00026 21.1 0.8 0.00042 20.4 0.5 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 EGF99002.1 - 0.00031 20.3 0.0 0.00034 20.1 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin PF00085.15 EGF99002.1 - 0.00038 20.0 0.1 0.00039 20.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EGF99002.1 - 0.00055 19.9 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EGF99002.1 - 0.001 18.8 0.1 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 EGF99002.1 - 0.0027 17.2 0.1 0.0032 17.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EGF99002.1 - 0.019 14.6 0.2 0.03 14.0 0.1 1.3 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_4 PF13462.1 EGF99002.1 - 0.046 13.7 1.5 0.25 11.3 0.4 2.0 1 1 1 2 2 2 0 Thioredoxin GST_N_2 PF13409.1 EGF99002.1 - 0.055 13.4 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 EGF99002.1 - 0.059 13.6 0.3 0.083 13.1 0.2 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) dCMP_cyt_deam_2 PF08211.6 EGF99002.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region GnsAB PF08178.6 EGF99002.1 - 0.73 9.5 5.5 0.78 9.4 0.4 2.8 3 0 0 3 3 3 0 GnsA/GnsB family UQ_con PF00179.21 EGF99003.1 - 2.1e-25 88.7 0.0 2.6e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGF99003.1 - 0.071 13.0 0.1 0.082 12.8 0.1 1.3 1 0 0 1 1 1 0 RWD domain PLA2_B PF01735.13 EGF99004.1 - 3.8e-65 219.9 0.1 1.8e-43 148.4 0.5 2.4 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.17 EGF99004.1 - 0.0018 18.2 2.0 0.0027 17.6 0.6 1.8 2 1 0 2 2 2 1 Patatin-like phospholipase PMBR PF09373.5 EGF99004.1 - 0.18 11.8 1.5 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Pseudomurein-binding repeat MFS_1 PF07690.11 EGF99005.1 - 8e-27 93.8 23.4 8e-27 93.8 16.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGF99005.1 - 0.00012 20.8 17.7 0.0002 20.0 11.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 EGF99005.1 - 0.00093 18.9 0.4 0.63 9.8 0.0 3.0 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.1 EGF99005.1 - 0.0074 14.7 24.2 0.027 12.8 3.6 3.2 1 1 2 3 3 3 2 MFS/sugar transport protein Polysacc_deac_1 PF01522.16 EGF99006.1 - 6.7e-29 100.0 0.0 9e-29 99.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase PTPlike_phytase PF14566.1 EGF99007.1 - 2.8e-07 30.6 1.0 6.9e-07 29.4 0.0 2.1 3 0 0 3 3 3 1 Inositol hexakisphosphate DSPc PF00782.15 EGF99007.1 - 1.5e-06 27.8 0.0 3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGF99007.1 - 0.00052 19.4 0.0 0.00096 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGF99007.1 - 0.0029 17.8 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 EGF99007.1 - 0.1 12.0 0.0 0.73 9.2 0.0 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Nudix_N_2 PF14803.1 EGF99008.1 - 0.18 11.5 1.8 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Nudix N-terminal FHA PF00498.21 EGF99009.1 - 1.4e-14 53.9 0.0 3.4e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain DUF4500 PF14937.1 EGF99009.1 - 0.05 13.4 1.1 0.14 12.0 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Atg14 PF10186.4 EGF99009.1 - 0.39 9.6 27.9 1.8 7.4 0.2 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EGF99009.1 - 0.48 9.4 31.2 0.076 12.0 0.2 2.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Sec20 PF03908.8 EGF99009.1 - 1.6 8.4 18.7 0.13 11.9 6.1 3.6 3 1 1 4 4 4 0 Sec20 DUF948 PF06103.6 EGF99009.1 - 4.3 7.2 12.6 0.51 10.2 2.5 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FliJ PF02050.11 EGF99013.1 - 0.023 14.7 0.6 0.074 13.1 0.4 1.9 1 0 0 1 1 1 0 Flagellar FliJ protein TMCO5 PF14992.1 EGF99013.1 - 0.14 11.2 5.3 1.3 8.0 0.5 2.2 1 1 1 2 2 2 0 TMCO5 family Lzipper-MIP1 PF14389.1 EGF99013.1 - 0.15 12.2 2.9 15 5.7 0.0 2.9 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 SlyX PF04102.7 EGF99013.1 - 0.23 11.8 5.8 0.35 11.2 0.6 3.2 2 1 1 3 3 3 0 SlyX FlaC_arch PF05377.6 EGF99013.1 - 0.24 11.3 1.7 14 5.7 0.1 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EGF99013.1 - 0.96 9.0 7.7 2.7 7.5 5.3 1.8 1 1 0 1 1 1 0 IncA protein Tropomyosin_1 PF12718.2 EGF99013.1 - 1.9 8.3 8.2 2 8.2 3.0 2.5 1 1 1 2 2 2 0 Tropomyosin like ATG16 PF08614.6 EGF99013.1 - 5.8 6.6 12.2 0.38 10.5 4.8 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) MatE PF01554.13 EGF99014.1 - 1.9e-54 183.6 22.5 2e-29 102.3 5.9 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EGF99014.1 - 0.00038 20.2 7.3 0.00038 20.2 5.0 3.9 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain D-aminoacyl_C PF07908.7 EGF99015.1 - 0.1 11.9 0.0 0.29 10.4 0.0 1.7 1 0 0 1 1 1 0 D-aminoacylase, C-terminal region FA_desaturase PF00487.19 EGF99016.1 - 5.3e-26 91.6 14.5 5.3e-26 91.6 10.0 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.5 EGF99016.1 - 4.5e-15 54.6 0.3 8.2e-15 53.7 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Pacifastin_I PF05375.8 EGF99017.1 - 4 7.0 10.0 3.5 7.2 0.2 3.3 3 1 1 4 4 4 0 Pacifastin inhibitor (LCMII) RRM_1 PF00076.17 EGF99019.1 - 0.00025 20.6 0.0 0.41 10.3 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGF99019.1 - 0.0017 18.2 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YIF1 PF03878.10 EGF99019.1 - 0.22 10.6 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 YIF1 AA_permease_2 PF13520.1 EGF99020.1 - 1.4e-34 119.3 33.1 2e-34 118.9 23.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGF99020.1 - 1.4e-13 49.9 30.2 2.4e-13 49.2 20.9 1.3 1 0 0 1 1 1 1 Amino acid permease RinB PF06116.7 EGF99020.1 - 0.019 14.5 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Transcriptional activator RinB DUF2591 PF10765.4 EGF99022.1 - 0.034 14.3 0.4 0.047 13.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2591) Coatomer_E PF04733.9 EGF99022.1 - 0.096 11.8 0.2 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit Daxx PF03344.10 EGF99026.1 - 0.51 8.7 5.9 0.59 8.5 4.1 1.0 1 0 0 1 1 1 0 Daxx Family CAP_C PF08603.6 EGF99029.1 - 0.012 14.9 0.6 0.015 14.6 0.4 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Kinocilin PF15033.1 EGF99029.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 1 0 1 1 1 0 Kinocilin protein Sec34 PF04136.10 EGF99031.1 - 0.018 14.7 1.0 0.03 14.0 0.0 1.7 2 0 0 2 2 2 0 Sec34-like family PGI PF00342.14 EGF99035.1 - 8.9e-211 700.4 0.1 1e-210 700.3 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase AA_permease_2 PF13520.1 EGF99036.1 - 3.1e-28 98.4 34.9 4.4e-28 97.9 24.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGF99036.1 - 4.3e-09 35.2 27.6 8.3e-09 34.3 19.1 1.5 1 1 0 1 1 1 1 Amino acid permease SpoVAB PF13782.1 EGF99036.1 - 0.0081 16.1 1.8 0.042 13.8 1.2 2.2 1 0 0 1 1 1 1 Stage V sporulation protein AB Ribosomal_L4 PF00573.17 EGF99037.1 - 1.5e-44 151.7 0.3 2.6e-44 150.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EGF99037.1 - 1.3e-24 85.8 0.9 1.3e-24 85.8 0.6 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain CAF-1_p150 PF11600.3 EGF99038.1 - 0.32 10.3 15.0 0.43 9.9 10.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4544 PF15077.1 EGF99038.1 - 2.2 7.7 4.2 3.2 7.1 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Peptidase_C12 PF01088.16 EGF99041.1 - 1.1e-57 194.6 0.0 1.3e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 TFIIA_gamma_N PF02268.11 EGF99042.1 - 9.3e-23 79.5 0.0 1.3e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EGF99042.1 - 1.1e-20 73.1 0.0 1.5e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF4339 PF14237.1 EGF99042.1 - 0.083 12.4 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) Cyt-b5 PF00173.23 EGF99044.1 - 7.4e-16 57.7 0.0 1.5e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EGF99044.1 - 1.7e-15 57.2 21.4 3.1e-15 56.3 14.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Glyco_transf_15 PF01793.11 EGF99049.1 - 2.3e-128 427.7 7.9 2.8e-128 427.5 5.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RRM_1 PF00076.17 EGF99050.1 - 8.6e-29 98.9 0.0 2.2e-14 52.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGF99050.1 - 1.9e-22 78.9 0.0 8.4e-11 41.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGF99050.1 - 2.5e-16 59.2 0.0 3e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGF99050.1 - 0.0096 15.7 0.0 0.094 12.5 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.3 EGF99050.1 - 0.061 13.0 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 GRP PF07172.6 EGF99050.1 - 5.8 7.4 15.3 0.12 12.8 3.6 2.4 2 1 0 2 2 2 0 Glycine rich protein family DDE_3 PF13358.1 EGF99051.1 - 6.1e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Abhydrolase_9_N PF15420.1 EGF99052.1 - 3.9 7.1 7.3 0.86 9.3 0.3 2.4 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus Polysacc_deac_1 PF01522.16 EGF99053.1 - 3.4e-30 104.2 0.0 4.8e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGF99053.1 - 0.00029 19.8 0.0 0.0019 17.1 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 Lipase_GDSL PF00657.17 EGF99054.1 - 1.6e-06 28.1 2.7 2.8e-06 27.3 1.9 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Borrelia_lipo_2 PF06238.6 EGF99054.1 - 0.073 13.1 1.9 10 6.1 0.3 2.5 2 0 0 2 2 2 0 Borrelia burgdorferi BBR25 lipoprotein EF-hand_1 PF00036.27 EGF99055.1 - 0.00087 18.4 0.1 0.0021 17.2 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EGF99055.1 - 0.012 14.8 0.1 0.034 13.5 0.1 1.6 1 0 0 1 1 1 0 EF hand DUF3184 PF11380.3 EGF99055.1 - 0.033 12.1 0.0 0.35 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3184) DctQ PF04290.7 EGF99055.1 - 0.047 13.4 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DCP1 PF06058.8 EGF99056.1 - 3.2e-21 75.6 0.0 5.7e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family Prothymosin PF03247.9 EGF99056.1 - 1.2 9.3 15.6 2.6 8.2 10.8 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family Peptidase_S49 PF01343.13 EGF99057.1 - 3.4e-38 130.8 0.0 3.3e-25 88.6 0.0 2.5 2 0 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.18 EGF99057.1 - 0.0079 15.8 0.4 0.041 13.5 0.2 2.2 2 0 0 2 2 2 1 Clp protease IDO PF01231.13 EGF99057.1 - 0.014 13.8 0.0 0.024 13.1 0.0 1.2 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase SDH_sah PF01972.11 EGF99057.1 - 0.096 11.4 0.1 0.19 10.4 0.1 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase TAF1D PF15333.1 EGF99058.1 - 0.0089 15.8 3.5 0.0098 15.7 2.4 1.1 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D DDRGK PF09756.4 EGF99058.1 - 3 7.2 11.1 3.3 7.0 7.7 1.1 1 0 0 1 1 1 0 DDRGK domain Bap31 PF05529.7 EGF99058.1 - 6.3 6.2 5.9 6.3 6.2 4.1 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Tol_Tol_Ttg2 PF05494.7 EGF99059.1 - 0.12 11.9 0.4 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Toluene tolerance, Ttg2 DUF676 PF05057.9 EGF99060.1 - 0.057 12.7 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_2 PF01674.13 EGF99061.1 - 0.0058 15.9 0.0 0.016 14.4 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_5 PF12695.2 EGF99061.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 EGF99061.1 - 0.025 13.8 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_M22 PF00814.20 EGF99062.1 - 5.5e-71 239.1 0.0 6.5e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family PilM_2 PF11104.3 EGF99062.1 - 0.0053 15.6 0.0 0.0085 15.0 0.0 1.2 1 0 0 1 1 1 1 Type IV pilus assembly protein PilM; BcrAD_BadFG PF01869.15 EGF99062.1 - 0.08 12.2 0.0 0.38 10.0 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Trehalose_PPase PF02358.11 EGF99063.1 - 1.3e-07 30.7 0.0 2e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EGF99063.1 - 0.0097 15.5 0.0 0.23 11.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EGF99063.1 - 0.03 13.6 0.1 0.075 12.3 0.0 1.6 1 1 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase JmjC PF02373.17 EGF99064.1 - 4.2e-42 142.9 0.7 6.2e-42 142.4 0.5 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EGF99064.1 - 2.6e-11 43.0 10.1 3.2e-11 42.7 5.5 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EGF99064.1 - 0.17 11.2 4.8 0.15 11.3 1.7 2.2 2 0 0 2 2 2 0 PHD-finger RINGv PF12906.2 EGF99064.1 - 1.8 8.6 7.9 3.6 7.6 5.5 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 EGF99064.1 - 1.8 8.3 6.8 0.7 9.6 2.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 EGF99064.1 - 5.1 7.0 13.2 4.7 7.1 5.7 2.9 3 1 0 3 3 3 0 Ring finger domain COesterase PF00135.23 EGF99065.1 - 4.2e-78 263.3 0.0 6.4e-78 262.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGF99065.1 - 0.013 15.0 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.23 EGF99066.1 - 4.9e-77 259.8 0.0 7.5e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.23 EGF99067.1 - 2.3e-75 254.3 0.0 9.3e-75 252.3 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family E1-E2_ATPase PF00122.15 EGF99068.1 - 2.4e-50 170.7 0.7 4.5e-50 169.8 0.5 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGF99068.1 - 8.9e-44 150.4 1.8 2.1e-43 149.2 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EGF99068.1 - 2.2e-21 75.7 0.0 2.4e-10 40.3 0.0 3.1 3 0 0 3 3 3 2 Heavy-metal-associated domain HAD PF12710.2 EGF99068.1 - 1.2e-13 51.6 0.0 2.4e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGF99068.1 - 7.4e-08 32.2 1.2 3.6e-05 23.4 0.2 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EGF99068.1 - 0.076 12.9 0.1 0.66 9.9 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TM_helix PF05552.7 EGF99068.1 - 0.19 11.3 4.1 2.3 7.9 1.3 2.6 2 0 0 2 2 2 0 Conserved TM helix COesterase PF00135.23 EGF99071.1 - 2.1e-93 313.9 0.0 2.9e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGF99071.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGF99071.1 - 0.026 13.7 0.3 0.072 12.3 0.2 1.6 1 1 1 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.23 EGF99072.1 - 3.3e-90 303.3 0.0 5.1e-90 302.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGF99072.1 - 0.0025 17.4 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EGF99073.1 - 1.8e-88 297.5 0.0 2.8e-88 296.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EGF99073.1 - 0.052 12.7 0.2 0.096 11.8 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EGF99073.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Trehalose_PPase PF02358.11 EGF99074.1 - 2e-39 134.8 0.8 6.8e-28 97.1 0.0 2.2 1 1 1 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.7 EGF99074.1 - 5.9e-08 32.5 0.0 9.2e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SOCS PF12610.3 EGF99075.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Suppressor of cytokine signalling SOCS PF12610.3 EGF99076.1 - 0.091 13.1 0.1 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Suppressor of cytokine signalling DUF966 PF06136.8 EGF99081.1 - 1.4 8.2 12.2 1.8 7.8 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RAP1 PF07218.6 EGF99081.1 - 5.9 4.8 9.2 7.4 4.5 6.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDC45 PF02724.9 EGF99082.1 - 4.7e-10 38.1 0.0 5.8e-10 37.8 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein LRR_2 PF07723.8 EGF99084.1 - 0.074 13.5 0.3 0.28 11.7 0.1 2.2 2 0 0 2 2 2 0 Leucine Rich Repeat DEAD PF00270.24 EGF99087.1 - 2.2e-42 144.4 0.5 6.2e-42 142.9 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGF99087.1 - 2.7e-28 97.6 0.1 5.8e-28 96.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EGF99087.1 - 0.0022 17.7 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EGF99087.1 - 0.0085 15.9 0.0 0.018 14.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EGF99087.1 - 0.014 14.7 0.1 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 EGF99087.1 - 0.03 14.4 0.2 0.086 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGF99087.1 - 0.042 13.4 0.1 0.093 12.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 EGF99087.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.9 EGF99087.1 - 0.16 11.7 0.7 0.44 10.2 0.0 2.2 2 2 0 2 2 2 0 Flavivirus DEAD domain Stm1_N PF09598.5 EGF99088.1 - 0.029 15.0 0.9 0.029 15.0 0.6 2.2 2 1 0 2 2 2 0 Stm1 P_C PF06640.6 EGF99088.1 - 0.056 13.4 1.7 0.069 13.1 1.2 1.1 1 0 0 1 1 1 0 P protein C-terminus VLPT PF07122.6 EGF99090.1 - 0.099 12.3 0.8 0.17 11.5 0.5 1.4 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) SNF2_N PF00176.18 EGF99091.1 - 7e-31 107.1 0.2 8.7e-31 106.8 0.1 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGF99091.1 - 1.3e-08 34.5 0.0 1.6e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGF99092.1 - 7.2e-11 41.7 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Alpha_kinase PF02816.13 EGF99093.1 - 2.6e-25 89.2 1.8 3.1e-25 88.9 1.3 1.2 1 0 0 1 1 1 1 Alpha-kinase family DUF762 PF05555.6 EGF99095.1 - 0.099 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF762) CDC50 PF03381.10 EGF99098.1 - 1.1e-96 323.2 0.2 4.3e-96 321.3 0.0 1.8 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.1 EGF99098.1 - 0.03 14.4 1.6 1.8 8.8 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) FCH PF00611.18 EGF99099.1 - 6e-13 48.7 0.8 6e-13 48.7 0.6 2.9 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Med28 PF11594.3 EGF99099.1 - 0.02 15.1 2.5 0.13 12.5 0.0 2.5 3 0 0 3 3 3 0 Mediator complex subunit 28 Fzo_mitofusin PF04799.8 EGF99099.1 - 0.025 13.9 1.1 0.069 12.5 0.7 1.7 1 0 0 1 1 1 0 fzo-like conserved region Sp100 PF03172.8 EGF99099.1 - 0.31 11.0 1.6 3.1 7.8 0.0 2.5 3 0 0 3 3 3 0 Sp100 domain DUF3378 PF11858.3 EGF99099.1 - 0.62 10.1 3.1 0.79 9.8 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3378) OmpH PF03938.9 EGF99099.1 - 7.7 6.4 12.3 26 4.7 8.5 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ATP-synt_ab PF00006.20 EGF99100.1 - 4e-109 363.1 0.0 5.8e-109 362.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGF99100.1 - 5.7e-20 71.8 0.4 1.2e-19 70.7 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGF99100.1 - 1.6e-14 53.8 2.5 5.2e-14 52.2 1.4 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain UBN2_3 PF14244.1 EGF99103.1 - 0.031 13.8 0.0 0.083 12.4 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type NatB_MDM20 PF09797.4 EGF99104.1 - 1.6e-50 171.8 13.5 3.5e-50 170.7 9.3 1.6 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_16 PF13432.1 EGF99104.1 - 0.00035 21.1 0.0 0.011 16.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGF99104.1 - 0.0061 16.1 0.5 0.056 13.1 0.2 2.3 2 0 0 2 2 2 1 TPR repeat Val_tRNA-synt_C PF10458.4 EGF99104.1 - 0.01 15.8 3.7 2.5 8.2 0.0 3.3 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm TPR_9 PF13371.1 EGF99104.1 - 0.038 13.8 0.0 4.4 7.2 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EGF99104.1 - 0.044 13.9 0.3 0.27 11.3 0.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1593 PF07632.6 EGF99104.1 - 0.074 12.3 0.2 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) TPR_14 PF13428.1 EGF99104.1 - 0.099 13.3 0.0 39 5.2 0.0 3.8 2 2 1 3 3 3 0 Tetratricopeptide repeat Ras PF00071.17 EGF99105.1 - 1.8e-58 196.4 0.5 2.3e-58 196.1 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGF99105.1 - 2.3e-20 73.2 0.2 5.7e-20 71.9 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGF99105.1 - 1e-16 60.6 0.5 1.2e-16 60.4 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGF99105.1 - 2.2e-08 33.7 0.1 1.1e-07 31.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGF99105.1 - 2e-06 27.1 0.1 3.1e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGF99105.1 - 1.9e-05 23.9 0.2 2.5e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGF99105.1 - 2.3e-05 24.3 0.1 3.9e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGF99105.1 - 0.00055 19.2 0.4 0.017 14.3 0.3 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 EGF99105.1 - 0.0046 17.0 0.0 0.6 10.2 0.0 2.7 1 1 1 2 2 2 1 AAA domain Dynamin_N PF00350.18 EGF99105.1 - 0.076 12.8 0.1 2.6 7.8 0.0 2.4 2 1 0 2 2 2 0 Dynamin family MobB PF03205.9 EGF99105.1 - 0.086 12.5 0.1 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2868 PF11067.3 EGF99105.1 - 0.14 11.2 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Peptidase_S8 PF00082.17 EGF99107.1 - 0.012 14.7 0.2 0.88 8.6 0.0 2.3 2 0 0 2 2 2 0 Subtilase family YqzE PF14038.1 EGF99107.1 - 4 7.2 9.6 0.38 10.5 0.1 2.8 2 0 0 2 2 2 0 YqzE-like protein COG4 PF08318.7 EGF99109.1 - 2.9e-07 29.5 0.0 3.5e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 COG4 transport protein LUC7 PF03194.10 EGF99112.1 - 4.7e-65 219.6 1.9 6.2e-65 219.2 1.3 1.1 1 0 0 1 1 1 1 LUC7 N_terminus DUF3418 PF11898.3 EGF99112.1 - 0.0013 17.2 1.2 0.0013 17.2 0.3 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF3418) Spt5_N PF11942.3 EGF99112.1 - 0.82 10.3 5.5 0.27 11.8 1.6 1.8 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Seryl_tRNA_N PF02403.17 EGF99112.1 - 1.5 8.9 6.9 19 5.3 4.8 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 EGF99112.1 - 4.3 7.3 10.8 1.7 8.5 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) MIP-T3 PF10243.4 EGF99113.1 - 6 5.2 24.7 6.3 5.1 17.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RabGAP-TBC PF00566.13 EGF99115.1 - 1e-37 129.6 0.3 1.6e-37 129.0 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Hist_deacetyl PF00850.14 EGF99116.1 - 1.8e-79 267.2 0.0 2.5e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain SHMT PF00464.14 EGF99117.1 - 1.2e-12 46.9 0.0 1.3e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase PROL5-SMR PF15621.1 EGF99119.1 - 0.65 10.4 5.3 1.2 9.5 3.7 1.4 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family MTHFR PF02219.12 EGF99120.1 - 1.8e-90 302.8 0.0 2.8e-90 302.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF222 PF02720.12 EGF99124.1 - 0.054 12.6 0.8 5.8 5.9 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF222) PLRV_ORF5 PF01690.12 EGF99124.1 - 0.11 11.5 9.8 0.14 11.2 6.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF843 PF05814.6 EGF99124.1 - 8.3 6.2 5.5 12 5.7 0.2 2.6 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF843) Tail_P2_I PF09684.5 EGF99125.1 - 0.093 12.2 0.1 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Phage tail protein (Tail_P2_I) Cullin PF00888.17 EGF99126.1 - 2.4e-28 99.0 0.1 3.7e-27 95.1 0.0 2.1 1 1 0 1 1 1 1 Cullin family Flg_hook PF02120.11 EGF99126.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK DUF3580 PF12117.3 EGF99129.1 - 0.011 15.7 1.0 1.6 8.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) Glycos_transf_2 PF00535.21 EGF99129.1 - 0.45 10.1 2.7 1.7 8.2 0.2 2.5 1 1 0 2 2 2 0 Glycosyl transferase family 2 ICMT PF04140.9 EGF99130.1 - 0.081 13.1 0.2 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family TRAM1 PF08390.6 EGF99131.1 - 0.0091 15.4 0.3 0.025 14.0 0.2 1.8 1 0 0 1 1 1 1 TRAM1-like protein DUF2305 PF10230.4 EGF99132.1 - 7.7e-50 169.7 0.1 1.2e-49 169.1 0.1 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EGF99132.1 - 2.4e-08 34.1 0.0 2.8e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGF99132.1 - 1.3e-05 24.9 0.1 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGF99132.1 - 0.00047 19.9 0.0 0.0011 18.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGF99132.1 - 0.0014 18.2 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 EGF99132.1 - 0.042 12.8 0.1 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 EGF99132.1 - 0.069 12.7 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Lipase (class 3) PE-PPE PF08237.6 EGF99132.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Ser_hydrolase PF06821.8 EGF99132.1 - 0.13 11.8 0.1 0.48 10.0 0.0 1.9 3 0 0 3 3 3 0 Serine hydrolase DUF2305 PF10230.4 EGF99133.1 - 1.3e-24 87.0 1.2 1.1e-22 80.7 0.1 2.3 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EGF99133.1 - 1.3e-06 28.1 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EGF99133.1 - 0.11 12.0 0.2 1 8.9 0.1 2.5 1 1 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 EGF99133.1 - 0.13 12.1 0.0 0.41 10.4 0.0 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family Sfi1 PF08457.5 EGF99134.1 - 4.5e-08 31.9 67.7 8.7e-06 24.4 29.2 4.0 1 1 2 3 3 3 2 Sfi1 spindle body protein LRR_8 PF13855.1 EGF99135.1 - 0.00019 21.1 8.6 0.011 15.4 0.8 4.9 4 2 2 6 6 6 1 Leucine rich repeat F-box PF00646.28 EGF99135.1 - 0.041 13.5 0.7 0.13 11.9 0.2 2.1 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 EGF99135.1 - 0.06 13.0 3.8 0.064 12.9 0.7 2.5 2 1 0 2 2 2 0 F-box-like GVQW PF13900.1 EGF99135.1 - 0.06 13.3 0.0 0.24 11.3 0.0 2.1 1 0 0 1 1 1 0 Putative binding domain DEAD PF00270.24 EGF99135.1 - 0.1 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase LRR_4 PF12799.2 EGF99135.1 - 1.2 8.8 8.7 0.97 9.1 0.2 4.3 2 2 1 4 4 4 0 Leucine Rich repeats (2 copies) zf-C3HC4 PF00097.20 EGF99138.1 - 1.4e-05 24.6 9.8 1.4e-05 24.6 6.8 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGF99138.1 - 8.7e-05 22.1 14.0 0.001 18.7 7.9 3.0 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGF99138.1 - 9.7e-05 22.1 10.2 9.7e-05 22.1 7.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGF99138.1 - 0.00016 21.6 12.3 0.00016 21.6 8.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGF99138.1 - 0.00025 20.8 10.3 0.00025 20.8 7.1 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EGF99138.1 - 0.0033 16.9 4.5 0.0033 16.9 3.1 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EGF99138.1 - 0.0095 15.6 8.8 0.011 15.4 2.8 2.7 3 0 0 3 3 3 1 zf-RING of BARD1-type protein Sgf11 PF08209.6 EGF99138.1 - 0.068 12.5 0.3 0.068 12.5 0.2 2.4 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-RING_UBOX PF13445.1 EGF99138.1 - 3.1 7.6 19.6 0.022 14.4 4.3 3.3 3 1 1 4 4 4 0 RING-type zinc-finger zf-Nse PF11789.3 EGF99139.1 - 2.5e-09 36.5 2.8 4.9e-09 35.5 1.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 EGF99139.1 - 3.6e-05 23.3 6.8 7.3e-05 22.3 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGF99139.1 - 0.00013 21.7 6.7 0.00013 21.7 4.6 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGF99139.1 - 0.00071 19.5 8.8 0.0016 18.4 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGF99139.1 - 0.0018 18.0 9.3 0.0025 17.5 5.7 1.8 2 0 0 2 2 2 1 Ring finger domain DUF3106 PF11304.3 EGF99139.1 - 0.018 15.4 2.6 0.027 14.8 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) zf-MIZ PF02891.15 EGF99139.1 - 0.031 13.7 7.8 0.062 12.8 5.4 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EGF99139.1 - 0.063 13.0 5.3 0.18 11.5 3.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EGF99139.1 - 0.26 11.0 10.7 0.52 10.0 7.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Ribosomal_S20p PF01649.13 EGF99139.1 - 2.9 8.3 0.0 2.9 8.3 0.0 3.0 3 0 0 3 3 3 0 Ribosomal protein S20 Ribosomal_60s PF00428.14 EGF99139.1 - 4.5 7.7 11.1 14 6.1 7.7 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein p450 PF00067.17 EGF99140.1 - 3.8e-68 230.0 0.0 5.3e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1374 PF07118.6 EGF99140.1 - 0.12 12.4 0.1 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) ACPS PF01648.15 EGF99144.1 - 7.2e-16 58.0 0.1 1.1e-15 57.4 0.1 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Glyco_hydro_71 PF03659.9 EGF99146.1 - 7.4e-53 179.3 2.7 1.2e-52 178.7 1.9 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 KAR9 PF08580.5 EGF99147.1 - 0.043 12.0 1.4 0.049 11.9 0.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF883 PF05957.8 EGF99152.1 - 4.7e-07 30.1 54.0 0.13 12.6 4.4 6.1 1 1 5 7 7 7 6 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EGF99152.1 - 0.0059 16.9 11.7 0.0059 16.9 8.1 6.8 1 1 2 3 3 3 2 YtxH-like protein ApoO PF09769.4 EGF99152.1 - 0.67 9.6 10.6 1.4 8.5 0.0 4.1 1 1 1 3 3 3 0 Apolipoprotein O DUF883 PF05957.8 EGF99154.1 - 6.1e-07 29.7 51.8 0.13 12.6 2.2 5.9 1 1 5 6 6 6 5 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EGF99154.1 - 0.0055 17.0 11.9 0.0055 17.0 8.2 6.6 1 1 2 3 3 3 2 YtxH-like protein ApoO PF09769.4 EGF99154.1 - 0.55 9.9 9.0 1.1 8.9 0.0 3.8 1 1 1 3 3 3 0 Apolipoprotein O PfkB PF00294.19 EGF99155.1 - 7.9e-63 212.3 0.1 9.1e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Abhydrolase_6 PF12697.2 EGF99156.1 - 8.1e-26 91.3 0.0 9.7e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGF99156.1 - 1.1e-13 51.3 0.0 2.4e-12 46.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGF99156.1 - 5.7e-11 42.3 0.0 9.6e-11 41.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGF99156.1 - 0.00061 19.2 0.0 0.0069 15.8 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EGF99156.1 - 0.00076 18.9 0.0 0.26 10.6 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF915 PF06028.6 EGF99156.1 - 0.0031 16.6 0.0 0.028 13.5 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 EGF99156.1 - 0.029 14.6 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.8 EGF99156.1 - 0.083 12.4 0.1 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Myb_DNA-binding PF00249.26 EGF99162.1 - 3.7e-10 39.6 0.0 1e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGF99162.1 - 0.0015 18.6 0.1 0.0048 16.9 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain PRY PF13765.1 EGF99163.1 - 0.068 12.7 0.0 0.26 10.8 0.0 1.9 1 0 0 1 1 1 0 SPRY-associated domain RNA_pol_Rpc34 PF05158.7 EGF99164.1 - 6.1e-75 252.4 6.5 8.4e-69 232.2 2.8 3.1 3 0 0 3 3 3 3 RNA polymerase Rpc34 subunit TrmB PF01978.14 EGF99164.1 - 8.7e-06 25.3 0.2 0.0013 18.3 0.0 3.2 4 0 0 4 4 4 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 EGF99164.1 - 1.2e-05 25.0 0.1 2.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_36 PF13730.1 EGF99164.1 - 0.0014 18.7 1.0 0.0025 17.9 0.2 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.17 EGF99164.1 - 0.011 15.4 0.1 0.031 13.9 0.1 1.8 1 0 0 1 1 1 0 MarR family PadR PF03551.9 EGF99164.1 - 0.017 14.8 0.1 0.075 12.8 0.0 2.1 3 0 0 3 3 3 0 Transcriptional regulator PadR-like family HTH_34 PF13601.1 EGF99164.1 - 0.02 14.9 1.3 0.033 14.2 0.1 2.0 2 0 0 2 2 1 0 Winged helix DNA-binding domain Rrf2 PF02082.15 EGF99164.1 - 0.04 14.0 0.2 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator HxlR PF01638.12 EGF99164.1 - 0.051 13.2 0.1 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 HxlR-like helix-turn-helix DUF2250 PF10007.4 EGF99164.1 - 0.11 12.4 0.7 3.9 7.4 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) RPA_C PF08784.6 EGF99164.1 - 0.46 10.9 6.4 0.25 11.7 0.2 2.7 2 1 1 3 3 3 0 Replication protein A C terminal Tetraspannin PF00335.15 EGF99165.1 - 0.082 12.1 9.8 0.22 10.7 6.8 1.7 1 1 0 1 1 1 0 Tetraspanin family CAP PF00188.21 EGF99166.1 - 9.5e-17 61.6 0.5 1.6e-16 60.9 0.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_S49_N PF08496.5 EGF99166.1 - 0.095 12.4 3.4 0.15 11.8 2.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Trypan_PARP PF05887.6 EGF99166.1 - 0.26 11.0 6.5 0.57 9.9 4.5 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2367 PF10164.4 EGF99168.1 - 0.038 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) zf-RING_2 PF13639.1 EGF99169.1 - 4.6e-15 55.1 9.6 6.4e-15 54.7 6.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGF99169.1 - 3.5e-09 36.6 5.3 6.4e-09 35.8 3.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGF99169.1 - 8e-06 25.4 7.0 1.1e-05 24.9 4.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGF99169.1 - 4e-05 23.1 11.1 6.1e-05 22.5 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGF99169.1 - 4.3e-05 23.4 10.5 6.4e-05 22.8 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGF99169.1 - 5.9e-05 22.7 8.7 8.4e-05 22.2 6.0 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGF99169.1 - 0.0095 15.7 5.7 0.034 13.9 4.0 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGF99169.1 - 0.067 12.9 6.5 0.048 13.3 2.7 2.0 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 EGF99169.1 - 3.3 7.7 10.4 65 3.6 7.3 2.6 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.6 EGF99169.1 - 4.4 7.3 7.6 6.4 6.8 5.2 1.3 1 0 0 1 1 1 0 RING-like domain 2-oxoacid_dh PF00198.18 EGF99170.1 - 2.5e-60 203.6 0.0 2.8e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) CENP-T PF15511.1 EGF99171.1 - 0.91 8.6 12.0 1.1 8.3 8.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 EGF99171.1 - 5.2 5.4 14.0 5.9 5.2 9.7 1.1 1 0 0 1 1 1 0 Daxx Family DUF2763 PF10961.3 EGF99171.1 - 9.8 6.6 11.4 4.6 7.7 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) API5 PF05918.6 EGF99172.1 - 2.2 6.7 8.1 3.1 6.1 5.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) 2-oxoacid_dh PF00198.18 EGF99173.1 - 6.3e-77 257.9 0.0 9.2e-77 257.4 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGF99173.1 - 3.7e-18 64.9 2.3 6.4e-18 64.1 0.5 2.2 2 1 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EGF99173.1 - 2.4e-13 49.4 0.1 5e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain DUF1675 PF07897.6 EGF99173.1 - 0.04 13.7 0.3 0.067 13.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) BIR PF00653.16 EGF99174.1 - 2.1e-08 34.4 0.9 2.2e-06 27.9 0.2 2.7 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain FATC PF02260.15 EGF99177.1 - 1.3e-05 24.4 0.5 3.6e-05 23.1 0.4 1.8 1 0 0 1 1 1 1 FATC domain RAP1 PF07218.6 EGF99178.1 - 0.44 8.5 6.9 0.51 8.3 4.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Strabismus PF06638.6 EGF99178.1 - 0.46 8.7 2.4 0.55 8.4 1.6 1.0 1 0 0 1 1 1 0 Strabismus protein P_C PF06640.6 EGF99178.1 - 3 7.7 11.9 5 7.0 8.2 1.4 1 1 0 1 1 1 0 P protein C-terminus FLO_LFY PF01698.11 EGF99179.1 - 0.25 10.1 2.3 0.28 9.9 1.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF566 PF04484.7 EGF99179.1 - 7.1 6.0 11.5 8.7 5.7 8.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) zf-RING_2 PF13639.1 EGF99180.1 - 5.8e-15 54.8 4.9 1e-14 54.0 3.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGF99180.1 - 3.2e-07 30.3 1.9 6.8e-07 29.3 1.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGF99180.1 - 1.3e-06 27.9 3.2 1.8e-06 27.4 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGF99180.1 - 7e-06 25.9 6.3 1.2e-05 25.2 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGF99180.1 - 1.5e-05 24.5 5.4 2.5e-05 23.8 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGF99180.1 - 0.00034 20.2 2.9 0.00055 19.6 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGF99180.1 - 0.00071 19.3 1.2 0.0015 18.3 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EGF99180.1 - 1.2 9.2 3.9 2.4 8.2 2.7 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EGF99180.1 - 2.3 8.1 5.6 5.1 7.0 3.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING HLH PF00010.21 EGF99181.1 - 0.011 15.4 0.0 0.038 13.6 0.0 2.0 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain DUF2714 PF10896.3 EGF99182.1 - 0.025 14.3 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2714) UBN2_2 PF14227.1 EGF99183.1 - 0.005 16.3 0.1 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF2833 PF11090.3 EGF99185.1 - 0.039 14.1 0.0 0.86 9.8 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2833) PEP-utilisers_N PF05524.8 EGF99186.1 - 0.051 13.3 0.4 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal SET PF00856.23 EGF99188.1 - 1.9e-13 51.0 0.0 4.9e-12 46.4 0.0 2.0 1 1 0 1 1 1 1 SET domain FAM86 PF14904.1 EGF99188.1 - 0.0073 16.0 0.0 0.0086 15.8 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function XRCC4 PF06632.7 EGF99190.1 - 0.02 13.7 0.2 0.035 12.9 0.1 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Sugar_tr PF00083.19 EGF99194.1 - 1.3e-121 406.3 27.1 1.6e-121 406.0 18.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGF99194.1 - 5.2e-18 64.8 49.3 2.3e-13 49.6 11.9 2.6 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGF99194.1 - 6.1e-09 34.7 24.1 7.9e-08 31.1 2.2 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 EGF99194.1 - 0.015 13.4 17.1 0.0097 14.0 6.0 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Pex24p PF06398.6 EGF99194.1 - 0.034 12.9 0.1 0.063 12.0 0.1 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Sugar_tr PF00083.19 EGF99195.1 - 2.1e-123 412.2 25.6 2.6e-123 411.9 17.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGF99195.1 - 7.1e-19 67.7 43.7 6.3e-15 54.7 8.6 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily Pex24p PF06398.6 EGF99195.1 - 0.04 12.7 0.1 0.075 11.8 0.1 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin MFS_3 PF05977.8 EGF99195.1 - 0.92 7.5 17.3 0.075 11.1 5.5 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DEAD PF00270.24 EGF99197.1 - 5.6e-28 97.5 0.1 1.6e-27 96.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGF99197.1 - 6.2e-24 83.6 0.3 1.3e-23 82.6 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EGF99197.1 - 0.023 14.6 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain COX5A PF02284.11 EGF99198.1 - 6.4e-19 67.9 0.1 6.7e-19 67.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va MIP PF00230.15 EGF99199.1 - 2.9e-16 59.6 11.4 6e-16 58.6 7.9 1.5 1 1 0 1 1 1 1 Major intrinsic protein F-box-like PF12937.2 EGF99201.1 - 1e-09 37.9 0.7 2.2e-09 36.9 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGF99201.1 - 9.5e-09 34.6 0.1 2.2e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain GAF PF01590.21 EGF99203.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EGF99203.1 - 0.0023 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 GAF domain KcnmB2_inactiv PF09303.5 EGF99204.1 - 0.12 12.2 0.2 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 KCNMB2, ball and chain domain DUF4611 PF15387.1 EGF99205.1 - 0.15 12.2 5.0 0.16 12.1 2.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) DUF3984 PF13136.1 EGF99206.1 - 0.021 14.0 0.1 0.025 13.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF4462 PF14692.1 EGF99206.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) EcKinase PF02958.15 EGF99207.1 - 0.03 13.4 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.17 EGF99209.1 - 1.6e-62 210.2 1.5 2e-62 209.8 0.0 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EGF99209.1 - 0.00051 19.8 0.2 0.086 12.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF4149 PF13664.1 EGF99210.1 - 3e-22 78.5 3.1 6.1e-22 77.5 2.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) Sugar_tr PF00083.19 EGF99212.1 - 6.5e-125 417.2 17.3 7.4e-125 417.0 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGF99212.1 - 1.5e-18 66.6 36.1 3.3e-12 45.7 12.2 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF4106 PF13388.1 EGF99217.1 - 0.082 11.8 0.0 0.084 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) GST_N PF02798.15 EGF99221.1 - 9e-15 54.6 0.0 2e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGF99221.1 - 2.1e-14 53.2 0.1 4.3e-14 52.2 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGF99221.1 - 1e-12 47.8 0.0 2.8e-12 46.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGF99221.1 - 1.4e-09 38.0 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGF99221.1 - 9.2e-06 26.0 0.1 2e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGF99221.1 - 1.7e-05 24.6 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EGF99221.1 - 0.052 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 MetRS-N binding domain DUF3785 PF12653.2 EGF99221.1 - 0.059 13.2 0.3 0.14 12.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3785) DUF2046 PF09755.4 EGF99222.1 - 4.8e-08 32.2 9.1 4.8e-08 32.2 6.3 1.9 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) SYCE1 PF15233.1 EGF99222.1 - 0.00015 21.6 0.9 0.00025 20.9 0.7 1.4 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 V_ATPase_I PF01496.14 EGF99222.1 - 0.63 7.8 3.4 0.79 7.4 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PspB PF06667.7 EGF99222.1 - 1.8 8.5 4.7 2.6 8.0 2.1 2.0 2 0 0 2 2 2 0 Phage shock protein B Frag1 PF10277.4 EGF99223.1 - 1.2e-27 96.8 13.3 1.2e-27 96.8 9.2 2.2 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 EGF99223.1 - 6e-05 23.1 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2183 PF09949.4 EGF99224.1 - 2.3e-28 98.0 0.1 9.1e-28 96.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF3439 PF11921.3 EGF99224.1 - 0.44 10.2 8.9 1.7 8.4 6.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Lipase_GDSL PF00657.17 EGF99225.1 - 5.3e-05 23.1 0.2 5.7e-05 23.0 0.1 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Tim17 PF02466.14 EGF99226.1 - 0.0094 15.9 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LRR_6 PF13516.1 EGF99227.1 - 1.6e-09 36.8 2.7 1.4 9.1 0.0 5.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.2 EGF99227.1 - 0.00034 20.1 15.6 0.064 12.9 0.2 5.2 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGF99227.1 - 0.0011 18.7 2.6 66 4.1 1.0 5.6 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.1 EGF99227.1 - 0.26 11.0 13.0 2.4 7.9 0.1 4.4 3 2 0 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 EGF99227.1 - 0.32 11.3 7.8 57 4.5 0.3 5.4 5 0 0 5 5 5 0 Leucine rich repeat DUF605 PF04652.11 EGF99227.1 - 3.7 6.8 22.1 5.1 6.3 15.3 1.1 1 0 0 1 1 1 0 Vta1 like Nop14 PF04147.7 EGF99227.1 - 3.8 5.3 10.8 5.2 4.8 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF572 PF04502.8 EGF99227.1 - 5 6.2 8.2 7.7 5.6 5.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pkinase PF00069.20 EGF99228.1 - 1.2e-58 198.3 0.0 1.3e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF99228.1 - 3.4e-32 111.5 0.0 4e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGF99228.1 - 0.0006 18.8 0.0 0.001 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGF99228.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EGF99228.1 - 0.067 12.2 0.0 0.17 10.9 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AMA-1 PF02430.10 EGF99230.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 DUF2677 PF10838.3 EGF99231.1 - 0.1 12.2 0.1 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) ILVD_EDD PF00920.16 EGF99232.1 - 3.4e-203 675.8 0.5 3.9e-203 675.6 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family EAP30 PF04157.11 EGF99233.1 - 1.3e-36 125.8 0.0 1.9e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EGF99233.1 - 1.8e-23 82.1 0.0 3.8e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 EGF99233.1 - 6.5e-05 21.9 12.1 0.0017 17.4 1.6 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DDE_Tnp_1_7 PF13843.1 EGF99233.1 - 0.0066 15.5 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 Transposase IS4 AalphaY_MDB PF04611.7 EGF99233.1 - 0.043 13.7 0.1 0.093 12.6 0.1 1.5 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region GRAM PF02893.15 EGF99233.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 GRAM domain DUF1845 PF08900.6 EGF99233.1 - 0.13 11.4 1.3 0.25 10.6 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) DZR PF12773.2 EGF99233.1 - 0.93 9.3 8.7 1.5 8.7 0.8 2.4 1 1 2 3 3 3 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 EGF99233.1 - 2.9 7.5 12.9 1.7 8.3 1.2 2.9 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger PAP2 PF01569.16 EGF99237.1 - 2.5e-11 43.3 5.3 2.5e-11 43.3 3.7 2.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EGF99237.1 - 2.6e-08 33.6 4.9 2.6e-08 33.6 3.4 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EGF99237.1 - 0.016 15.5 5.9 0.016 15.5 4.1 3.0 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Peptidase_C74 PF12387.3 EGF99237.1 - 0.11 11.6 0.1 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Pestivirus NS2 peptidase zf-C2H2 PF00096.21 EGF99238.1 - 3e-08 33.5 9.6 0.00031 20.8 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGF99238.1 - 1.5e-05 25.0 9.0 0.0055 16.9 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGF99238.1 - 0.0013 18.8 8.5 0.13 12.4 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EGF99238.1 - 0.0033 17.6 0.5 0.0033 17.6 0.4 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2HC_2 PF13913.1 EGF99238.1 - 0.029 14.0 0.1 0.029 14.0 0.0 2.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EGF99238.1 - 0.035 14.0 3.8 0.052 13.4 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 EGF99238.1 - 0.041 14.0 7.2 0.15 12.2 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF1418 PF07214.7 EGF99239.1 - 0.1 12.2 0.0 0.34 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) BTB_2 PF02214.17 EGF99240.1 - 5.9e-06 26.3 0.1 2.2e-05 24.5 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain RCC1 PF00415.13 EGF99241.1 - 1e-53 179.3 19.3 2.2e-09 37.3 0.0 8.1 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGF99241.1 - 6e-30 102.1 36.7 1.9e-07 30.5 1.3 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Sugar_tr PF00083.19 EGF99243.1 - 1.2e-126 422.9 23.1 1.4e-126 422.7 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGF99243.1 - 1.5e-24 86.3 30.7 5.3e-13 48.4 8.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily YrhC PF14143.1 EGF99243.1 - 10 6.1 7.4 1 9.3 1.4 2.2 2 0 0 2 2 2 0 YrhC-like protein Sugar_tr PF00083.19 EGF99244.1 - 3.6e-125 418.0 21.7 4.1e-125 417.8 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGF99244.1 - 3.9e-24 85.0 30.1 8.3e-14 51.0 7.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Cation_efflux PF01545.16 EGF99244.1 - 0.05 12.6 11.7 0.39 9.7 0.8 3.0 2 1 1 3 3 3 0 Cation efflux family RRM_1 PF00076.17 EGF99245.1 - 1e-45 153.2 1.9 7.9e-18 63.8 0.0 5.7 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGF99245.1 - 7.7e-33 112.3 0.1 4.7e-12 45.7 0.0 6.0 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGF99245.1 - 1e-10 41.2 0.3 0.0003 20.5 0.0 4.4 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_22 PF03901.12 EGF99246.1 - 4.9e-86 289.3 17.9 1.9e-84 284.1 12.4 2.0 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family MSP PF01716.13 EGF99247.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide RR_TM4-6 PF06459.7 EGF99248.1 - 0.067 13.0 2.1 0.073 12.9 1.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EGF99248.1 - 0.14 11.5 6.0 0.15 11.3 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Mpp10 PF04006.7 EGF99248.1 - 1.4 7.1 13.1 1.6 7.0 9.1 1.0 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.7 EGF99248.1 - 4.7 4.9 15.7 5 4.9 10.9 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 EGF99248.1 - 5.3 5.9 6.2 6.3 5.7 4.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 EGF99248.1 - 6.3 5.1 11.8 6.7 5.0 8.2 1.0 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EGF99248.1 - 7.1 5.8 13.8 7.6 5.7 9.6 1.1 1 0 0 1 1 1 0 SDA1 RTC4 PF14474.1 EGF99249.1 - 1.3e-13 50.9 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain zf-CCHC_4 PF14392.1 EGF99249.1 - 0.009 15.6 0.7 0.017 14.7 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGF99249.1 - 1.9 8.5 9.4 0.051 13.5 2.3 1.6 2 0 0 2 2 2 0 Zinc knuckle DUF1014 PF06244.7 EGF99250.1 - 1.8e-24 86.3 11.8 1.3e-23 83.5 8.1 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) NUDIX PF00293.23 EGF99252.1 - 3.3e-09 36.5 0.1 4e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Ashwin PF15323.1 EGF99254.1 - 9.1 6.2 14.0 3.5 7.5 3.3 2.7 2 1 1 3 3 3 0 Developmental protein FYVE_2 PF02318.11 EGF99258.1 - 0.35 10.7 2.8 0.46 10.4 1.9 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger LMP PF04778.7 EGF99262.1 - 0.029 14.1 2.3 0.039 13.7 1.6 1.2 1 0 0 1 1 1 0 LMP repeated region Dor1 PF04124.7 EGF99263.1 - 1.3e-35 122.5 11.5 2.4e-30 105.1 6.1 3.3 2 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 EGF99263.1 - 0.00093 18.9 3.4 0.014 15.2 0.3 3.4 3 0 0 3 3 3 1 Vps51/Vps67 HALZ PF02183.13 EGF99263.1 - 0.009 15.7 0.3 0.068 12.9 0.0 2.4 2 0 0 2 2 2 1 Homeobox associated leucine zipper AP_endonuc_2 PF01261.19 EGF99264.1 - 1.4e-15 57.1 0.0 1.6e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Peptidase_C54 PF03416.14 EGF99265.1 - 0.00025 20.2 0.0 0.00042 19.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C54 TRAM_LAG1_CLN8 PF03798.11 EGF99266.1 - 2.1e-33 115.5 21.4 2.1e-33 115.5 14.8 1.9 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EGF99266.1 - 3.1e-17 61.8 0.2 7.3e-17 60.6 0.2 1.7 1 0 0 1 1 1 1 TRAM1-like protein Ribosomal_S28e PF01200.13 EGF99267.1 - 5.5e-28 96.5 0.4 5.8e-28 96.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e adh_short PF00106.20 EGF99268.1 - 8.3e-12 45.3 0.2 5.4e-11 42.7 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGF99268.1 - 0.00016 21.3 0.1 0.047 13.3 0.0 2.2 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 EGF99268.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding ATP11 PF06644.6 EGF99270.1 - 1.3e-69 234.7 8.9 1.7e-69 234.3 6.2 1.2 1 0 0 1 1 1 1 ATP11 protein DUF515 PF04415.7 EGF99270.1 - 0.062 11.5 9.7 0.083 11.1 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Spore_II_R PF09551.5 EGF99270.1 - 1.2 9.1 5.5 3.1 7.8 3.6 1.9 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) MFS_1 PF07690.11 EGF99271.1 - 1e-42 146.1 45.1 2.9e-37 128.1 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGF99271.1 - 7.2e-13 47.9 19.7 9.3e-12 44.2 13.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter PAS PF00989.19 EGF99273.1 - 0.00053 19.7 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 EGF99273.1 - 0.00058 19.7 10.1 0.00058 19.7 7.0 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EGF99274.1 - 5.6e-31 107.5 30.8 9.9e-31 106.7 21.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGF99274.1 - 6.7e-12 44.7 23.6 2.4e-11 42.8 16.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter SET PF00856.23 EGF99275.1 - 1.3e-06 28.7 0.0 2.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 SET domain SET PF00856.23 EGF99276.1 - 4.9e-08 33.4 0.0 1.1e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 SET domain RdRP PF05183.7 EGF99278.1 - 1.5e-46 159.3 0.0 4.3e-32 111.5 0.0 3.3 1 1 1 2 2 2 2 RNA dependent RNA polymerase SET PF00856.23 EGF99279.1 - 3.4e-06 27.4 0.0 1e-05 25.8 0.0 1.7 1 1 0 1 1 1 1 SET domain Glyco_transf_90 PF05686.7 EGF99281.1 - 6.1e-05 21.8 0.0 0.00016 20.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 PseudoU_synth_1 PF01416.15 EGF99282.1 - 1.9e-15 57.1 0.0 2.8e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase ORC6 PF05460.8 EGF99282.1 - 4.1 6.4 17.9 2.8 6.9 5.3 2.3 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) ECH PF00378.15 EGF99283.1 - 2.7e-33 115.1 0.0 4.9e-33 114.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Med12 PF09497.5 EGF99284.1 - 1.8e-25 88.7 0.8 4.3e-25 87.4 0.2 2.1 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 EGF99284.1 - 0.0051 15.3 1.4 0.012 14.1 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain PLA2_B PF01735.13 EGF99285.1 - 1.5e-92 310.3 2.8 1.9e-84 283.6 0.1 2.9 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.17 EGF99285.1 - 0.024 14.5 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Patatin-like phospholipase NPV_P10 PF05531.7 EGF99286.1 - 0.051 13.8 0.1 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF455 PF04305.9 EGF99289.1 - 0.13 11.5 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF455) Glyco_hydro_47 PF01532.15 EGF99291.1 - 2.1e-95 320.0 0.0 2.6e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Oxysterol_BP PF01237.13 EGF99292.1 - 1.2e-123 412.1 0.0 1.8e-123 411.5 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Ank PF00023.25 EGF99292.1 - 3.1e-15 55.1 2.7 5.7e-05 22.7 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EGF99292.1 - 1.3e-14 54.2 0.3 1e-09 38.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGF99292.1 - 3.4e-13 49.3 1.7 1.3e-06 28.4 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGF99292.1 - 2.8e-11 42.5 0.2 0.0017 18.4 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EGF99292.1 - 4.5e-10 39.7 0.2 2.8e-05 24.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.24 EGF99292.1 - 1e-09 38.5 0.0 2.6e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EGF99292.1 - 0.00015 21.7 0.3 0.00057 19.8 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Sars6 PF12133.3 EGF99293.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus SET PF00856.23 EGF99294.1 - 1.9e-05 25.0 0.1 0.00094 19.5 0.0 3.0 2 1 0 2 2 2 1 SET domain SET PF00856.23 EGF99295.1 - 1.9e-06 28.2 0.1 7.7e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 SET domain MFS_1 PF07690.11 EGF99296.1 - 4.4e-26 91.4 23.4 4.4e-26 91.4 16.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGF99296.1 - 3.2e-08 32.5 18.1 7.6e-08 31.3 12.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGF99297.1 - 2.3e-37 128.5 47.5 4.6e-36 124.2 16.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGF99297.1 - 1.6e-08 33.5 20.7 1.6e-08 33.5 14.3 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EGF99297.1 - 0.063 11.3 13.0 0.016 13.3 1.6 2.6 2 1 0 3 3 3 0 Transmembrane secretion effector MFS_1 PF07690.11 EGF99298.1 - 2.2e-18 66.1 23.3 2.2e-18 66.1 16.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGF99298.1 - 0.00035 19.2 20.2 0.014 13.9 14.0 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EGF99298.1 - 0.0004 18.9 0.7 0.0004 18.9 0.5 3.2 3 1 0 3 3 3 1 MFS/sugar transport protein MFS_1 PF07690.11 EGF99299.1 - 1.1e-23 83.5 13.6 1.1e-23 83.5 9.4 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGF99299.1 - 1.4e-10 40.3 8.5 2.3e-10 39.6 5.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 EGF99299.1 - 6.5e-05 21.2 1.4 0.00012 20.3 1.0 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector YfzA PF14118.1 EGF99299.1 - 0.058 13.5 0.3 0.21 11.6 0.2 1.9 1 0 0 1 1 1 0 YfzA-like protein MFS_2 PF13347.1 EGF99299.1 - 0.34 9.2 16.8 0.0079 14.6 3.3 2.9 2 1 2 4 4 4 0 MFS/sugar transport protein PRA1 PF03208.14 EGF99300.1 - 1e-39 135.3 0.1 1.2e-39 135.0 0.1 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF3007 PF11460.3 EGF99301.1 - 0.15 12.1 0.4 0.22 11.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) U79_P34 PF03064.11 EGF99301.1 - 0.2 11.1 7.6 0.26 10.7 5.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 zf-C2H2 PF00096.21 EGF99303.1 - 5.7e-13 48.3 5.1 1.3e-06 28.4 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGF99303.1 - 1e-09 38.0 2.7 0.00028 20.9 0.3 2.8 2 1 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGF99303.1 - 7.3e-09 35.4 6.6 1.2e-06 28.5 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGF99303.1 - 6.7e-08 32.4 0.1 0.0022 18.0 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGF99303.1 - 5.4e-06 26.4 3.4 0.0053 16.9 0.4 3.1 3 0 0 3 3 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGF99303.1 - 0.00044 20.0 1.6 0.21 11.5 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EGF99303.1 - 0.0023 17.5 2.9 0.029 14.0 0.2 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Endonuclease_7 PF02945.10 EGF99303.1 - 0.026 14.2 2.8 1.3 8.7 2.0 2.2 1 1 1 2 2 2 0 Recombination endonuclease VII FdhE PF04216.7 EGF99303.1 - 0.035 13.8 0.5 0.046 13.4 0.4 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-Di19 PF05605.7 EGF99303.1 - 0.042 13.9 1.2 0.083 13.0 0.8 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 EGF99303.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 GAGA factor zf-RING_3 PF14369.1 EGF99303.1 - 0.24 11.4 2.5 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 zinc-finger FYVE PF01363.16 EGF99303.1 - 0.84 9.5 3.3 3.3 7.6 1.7 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-BED PF02892.10 EGF99303.1 - 1.8 8.4 4.6 1.1 9.0 0.8 2.1 1 1 1 2 2 2 0 BED zinc finger Clat_adaptor_s PF01217.15 EGF99304.1 - 1.3e-48 164.3 0.9 1.6e-48 164.0 0.6 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pro_isomerase PF00160.16 EGF99307.1 - 2.2e-43 148.1 0.2 2.9e-43 147.7 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NAP PF00956.13 EGF99308.1 - 2.3e-80 269.2 1.0 2.3e-80 269.2 0.7 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) FAM176 PF14851.1 EGF99308.1 - 0.57 9.8 5.2 6.8 6.3 0.8 2.5 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.8 EGF99308.1 - 4.4 6.8 21.1 0.21 11.2 0.3 2.4 2 1 0 2 2 2 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 EGF99308.1 - 6.4 4.4 7.2 0.2 9.5 0.3 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RXT2_N PF08595.6 EGF99308.1 - 6.4 6.5 10.8 5.4 6.7 3.5 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal HSP70 PF00012.15 EGF99330.1 - 0.8 7.5 9.2 1 7.1 6.4 1.1 1 0 0 1 1 1 0 Hsp70 protein Mannosyl_trans3 PF11051.3 EGF99333.1 - 4.2e-27 95.1 0.1 1.5e-17 63.8 0.0 3.0 2 1 0 2 2 2 2 Mannosyltransferase putative DUF3678 PF12435.3 EGF99333.1 - 1.9 8.1 4.8 0.56 9.8 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) rRNA_processing PF08524.6 EGF99335.1 - 9.6e-06 25.4 18.6 4.8e-05 23.1 1.9 2.8 2 1 0 2 2 2 2 rRNA processing PALP PF00291.20 EGF99336.1 - 0.00059 19.1 0.0 0.00059 19.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cation_efflux PF01545.16 EGF99340.1 - 7.4e-11 41.6 4.7 9.3e-11 41.3 3.3 1.1 1 0 0 1 1 1 1 Cation efflux family C1_2 PF03107.11 EGF99341.1 - 1 9.5 4.0 16 5.7 0.2 2.7 2 0 0 2 2 2 0 C1 domain WD40 PF00400.27 EGF99342.1 - 6.8e-25 85.9 19.3 5.4e-09 35.6 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Peptidase_M20 PF01546.23 EGF99342.1 - 1.1e-22 80.4 0.0 2.4e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGF99342.1 - 2.7e-10 39.9 0.0 4.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.3 EGF99342.1 - 0.00013 20.3 2.3 0.25 9.4 0.0 3.4 2 1 1 4 4 4 2 Nucleoporin Nup120/160 OPT PF03169.10 EGF99343.1 - 1.2e-133 446.8 49.5 3.1e-133 445.4 34.3 1.6 1 1 0 1 1 1 1 OPT oligopeptide transporter protein BPL_LplA_LipB PF03099.14 EGF99344.1 - 1.8e-17 63.5 0.0 3.7e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 EGF99344.1 - 2.8e-05 23.7 0.1 0.0001 21.8 0.1 2.0 1 1 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus DUF2457 PF10446.4 EGF99348.1 - 3.5e-05 22.7 11.6 7.2e-05 21.6 8.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 EGF99348.1 - 0.33 11.2 13.7 1 9.7 9.5 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tom22 PF04281.8 EGF99348.1 - 1.5 8.3 10.3 0.13 11.7 2.6 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 RXT2_N PF08595.6 EGF99348.1 - 3.7 7.3 9.8 0.62 9.8 4.0 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EGF99348.1 - 4.3 6.8 8.7 8.9 5.8 6.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin HTH_32 PF13565.1 EGF99349.1 - 0.027 15.2 0.2 0.057 14.2 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Nudix_N PF12535.3 EGF99350.1 - 0.03 13.7 0.0 0.084 12.3 0.0 1.8 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Tmemb_9 PF05434.6 EGF99350.1 - 0.066 12.9 0.8 0.26 11.0 0.2 2.1 2 0 0 2 2 2 0 TMEM9 GHL1-3 PF11308.3 EGF99351.1 - 0.035 13.4 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 PUA PF01472.15 EGF99354.1 - 1.4e-17 63.1 0.0 2.2e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 PUA domain Sir1 PF11603.3 EGF99355.1 - 0.0012 18.9 1.2 0.0018 18.4 0.2 1.6 2 0 0 2 2 2 1 Regulatory protein Sir1 Glycos_trans_3N PF02885.12 EGF99355.1 - 0.1 12.1 0.3 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain HTH_24 PF13412.1 EGF99355.1 - 0.11 11.8 0.1 0.29 10.5 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CTP_transf_2 PF01467.21 EGF99356.1 - 2.5e-12 47.1 0.1 3.8e-12 46.5 0.1 1.3 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 EGF99356.1 - 0.052 13.1 1.2 0.072 12.7 0.3 1.7 2 1 0 2 2 2 0 FAD synthetase API5 PF05918.6 EGF99359.1 - 0.13 10.7 3.9 0.19 10.1 2.7 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SBP_bac_10 PF07596.6 EGF99360.1 - 0.045 13.7 0.4 0.049 13.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) Prefoldin_2 PF01920.15 EGF99362.1 - 0.04 13.6 0.8 0.04 13.6 0.6 2.8 2 1 1 3 3 3 0 Prefoldin subunit FemAB PF02388.11 EGF99362.1 - 0.071 11.7 0.2 0.21 10.2 0.0 1.8 2 0 0 2 2 2 0 FemAB family SlyX PF04102.7 EGF99362.1 - 0.15 12.4 4.3 0.59 10.5 3.0 2.1 1 0 0 1 1 1 0 SlyX SNF2_N PF00176.18 EGF99365.1 - 1.1e-50 172.1 2.5 6.2e-29 100.7 0.2 2.0 1 1 1 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.10 EGF99365.1 - 0.00075 19.3 0.1 0.0079 16.0 0.0 2.0 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.24 EGF99365.1 - 0.004 16.6 0.1 0.79 9.2 0.0 2.2 1 1 1 2 2 2 2 DEAD/DEAH box helicase Zot PF05707.7 EGF99365.1 - 0.022 14.2 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF2075 PF09848.4 EGF99365.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Helicase_C PF00271.26 EGF99366.1 - 1.6e-06 27.8 0.0 3.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Env-gp36 PF09590.5 EGF99366.1 - 0.07 11.3 0.1 0.079 11.1 0.1 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein FAR1 PF03101.10 EGF99367.1 - 8.5e-05 23.0 0.0 0.0016 18.8 0.0 2.4 2 0 0 2 2 2 1 FAR1 DNA-binding domain Peptidase_C65 PF10275.4 EGF99367.1 - 0.0013 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EGF99367.1 - 0.0014 19.2 0.0 0.0032 18.0 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease DUF1730 PF08331.5 EGF99368.1 - 0.052 13.2 0.0 5.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1730) TFIIA PF03153.8 EGF99368.1 - 0.87 9.4 14.6 2 8.2 10.1 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF498 PF04430.9 EGF99370.1 - 1.3e-15 56.8 0.0 1.8e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) RNase_T PF00929.19 EGF99371.1 - 6.2e-13 49.3 0.0 1.1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EGF99375.1 - 6.1e-16 58.3 0.5 8.9e-16 57.8 0.3 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HATPase_c_5 PF14501.1 EGF99375.1 - 0.052 13.2 0.1 0.097 12.3 0.1 1.4 1 0 0 1 1 1 0 GHKL domain ADK PF00406.17 EGF99377.1 - 1.2e-13 51.2 0.0 1.3e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EGF99377.1 - 1.2e-11 44.0 0.0 1.6e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase, active site lid ADIP PF11559.3 EGF99380.1 - 0.019 14.8 2.1 0.23 11.3 0.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 EGF99380.1 - 0.047 13.5 4.4 3.7 7.4 0.4 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EGF99380.1 - 0.63 9.6 4.6 2.4 7.7 3.2 1.8 1 1 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 EGF99380.1 - 1.1 9.0 8.6 4.7 7.0 5.9 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.7 EGF99380.1 - 2.6 8.0 5.7 2.4 8.1 0.2 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Uds1 PF15456.1 EGF99380.1 - 4.4 7.3 7.8 37 4.3 4.8 2.3 1 1 0 1 1 1 0 Up-regulated During Septation DUF3987 PF13148.1 EGF99388.1 - 2.6 6.5 15.2 4 5.8 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RPAP3_C PF13877.1 EGF99390.1 - 9.7e-12 44.7 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_11 PF13414.1 EGF99390.1 - 4.5e-08 32.6 0.1 0.0011 18.5 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGF99390.1 - 6.3e-07 28.8 0.2 0.0002 21.0 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGF99390.1 - 2.2e-06 27.0 0.0 0.0005 19.5 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGF99390.1 - 0.0014 18.3 0.1 0.011 15.6 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat ERCC4 PF02732.10 EGF99391.1 - 2.2e-20 72.8 0.6 4.1e-20 72.0 0.4 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EGF99391.1 - 0.0017 18.4 0.2 0.0041 17.2 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 EGF99391.1 - 0.067 12.9 0.2 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF11 PF01345.13 EGF99392.1 - 0.0026 17.7 1.6 3.8 7.6 0.1 3.3 3 0 0 3 3 3 2 Domain of unknown function DUF11 SNN_cytoplasm PF09051.5 EGF99392.1 - 1 9.1 8.2 37 4.1 0.1 4.5 4 0 0 4 4 4 0 Stannin cytoplasmic FAR1 PF03101.10 EGF99393.1 - 0.064 13.7 0.5 0.064 13.7 0.3 2.4 2 1 0 2 2 2 0 FAR1 DNA-binding domain UBN2 PF14223.1 EGF99396.1 - 0.03 14.1 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGF99396.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 EGF99396.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Toxin_44 PF15523.1 EGF99398.1 - 0.068 13.0 1.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 Putative toxin 44 GEMIN8 PF15348.1 EGF99398.1 - 1.1 9.3 12.5 0.3 11.0 1.0 3.1 3 0 0 3 3 3 0 Gemini of Cajal bodies-associated protein 8 HTH_23 PF13384.1 EGF99401.1 - 0.11 12.1 1.5 5.8 6.7 0.0 3.0 2 0 0 2 2 2 0 Homeodomain-like domain BP28CT PF08146.7 EGF99404.1 - 3.8e-28 98.1 0.2 3.8e-28 98.1 0.1 3.0 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EGF99404.1 - 2.2e-09 37.2 0.6 2.2e-09 37.2 0.4 5.1 4 2 1 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 EGF99404.1 - 0.0004 20.2 0.4 0.014 15.4 0.1 4.1 2 0 0 2 2 2 1 HEAT repeat Pkinase PF00069.20 EGF99407.1 - 0.0041 16.3 0.0 0.029 13.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF99407.1 - 0.046 12.7 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Polysacc_deac_1 PF01522.16 EGF99408.1 - 6.2e-27 93.6 0.0 1.6e-26 92.3 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGF99408.1 - 5.1e-05 22.3 0.1 0.00019 20.4 0.0 1.8 2 1 1 3 3 3 1 Glycosyl hydrolase family 57 ABC1 PF03109.11 EGF99410.1 - 2.2e-27 95.4 0.0 4.1e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 EGF99410.1 - 3.5e-05 23.0 0.1 0.099 11.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.18 EGF99410.1 - 0.00034 20.4 0.0 0.00076 19.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGF99410.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family RRM_1 PF00076.17 EGF99412.1 - 6.6e-20 70.5 0.0 4.5e-10 39.0 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGF99412.1 - 1.1e-13 50.7 0.0 3.3e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGF99412.1 - 1.9e-11 43.7 0.0 1e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) APH PF01636.18 EGF99414.1 - 7.1e-34 117.5 0.0 8.8e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGF99414.1 - 3.5e-10 39.8 0.0 9e-09 35.2 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 EGF99414.1 - 1.5e-06 27.5 0.0 2.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.20 EGF99414.1 - 0.046 12.8 0.0 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.6 EGF99414.1 - 0.088 11.4 0.2 0.97 7.9 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1679) Sec23_trunk PF04811.10 EGF99415.1 - 0.12 11.7 0.1 3.1 7.1 0.0 2.3 1 1 1 2 2 2 0 Sec23/Sec24 trunk domain LRR_4 PF12799.2 EGF99416.1 - 0.0093 15.5 11.2 5.1 6.8 0.1 6.4 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) Myotub-related PF06602.9 EGF99418.1 - 1.4e-124 415.4 1.2 1.8e-124 415.0 0.8 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 EGF99418.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGF99418.1 - 0.014 15.6 0.0 0.035 14.3 0.0 1.8 1 1 0 1 1 1 0 Tyrosine phosphatase family Spc97_Spc98 PF04130.8 EGF99420.1 - 5.4e-102 341.8 2.9 7.3e-102 341.4 2.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family BTB PF00651.26 EGF99421.1 - 2.7e-08 33.7 0.0 2.4e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain CUE PF02845.11 EGF99422.1 - 4.1e-07 29.3 0.1 7.1e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 CUE domain zf-C2H2 PF00096.21 EGF99424.1 - 4.4e-06 26.7 1.6 1.5e-05 25.0 1.1 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGF99424.1 - 0.0031 17.7 2.0 0.0077 16.4 1.4 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EGF99424.1 - 0.027 14.7 0.8 0.097 12.9 0.5 2.1 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EGF99424.1 - 0.27 11.5 4.5 0.91 9.9 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double domain MMPL PF03176.10 EGF99426.1 - 0.06 12.0 1.6 0.071 11.8 1.1 1.1 1 0 0 1 1 1 0 MMPL family DUF900 PF05990.7 EGF99427.1 - 0.027 13.8 1.1 2 7.7 0.1 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Cript PF10235.4 EGF99427.1 - 0.038 14.3 1.6 0.038 14.3 1.1 2.0 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT HypA PF01155.14 EGF99427.1 - 0.2 11.3 1.3 0.43 10.2 0.9 1.6 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Membr_traf_MHD PF10540.4 EGF99428.1 - 2.8e-18 66.0 0.2 1.3e-17 63.9 0.0 2.3 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EGF99428.1 - 3.6e-08 33.1 0.0 6.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain PMSR PF01625.16 EGF99429.1 - 3.7e-57 192.5 3.9 4.4e-57 192.3 2.7 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase HHH_8 PF14716.1 EGF99429.1 - 0.082 13.1 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain EcKinase PF02958.15 EGF99430.1 - 0.099 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase C2 PF00168.25 EGF99433.1 - 1.6e-06 27.8 0.0 0.0022 17.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain DUF3006 PF11213.3 EGF99435.1 - 0.015 15.0 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) UME PF08064.8 EGF99436.1 - 1.1e-16 60.7 0.7 3.9e-16 58.9 0.1 2.4 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.18 EGF99436.1 - 9.7e-07 28.0 0.2 1.9e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 FAT domain Nitrate_red_gam PF02665.9 EGF99438.1 - 0.071 12.4 0.2 0.071 12.4 0.1 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Aldo_ket_red PF00248.16 EGF99440.1 - 1.3e-42 145.6 0.0 1.6e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_92 PF07971.7 EGF99442.1 - 1.5e-44 152.4 3.1 2.1e-44 152.0 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 RRM_6 PF14259.1 EGF99443.1 - 0.0009 19.1 0.1 0.0024 17.8 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGF99443.1 - 0.0015 18.3 0.2 0.015 15.1 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGF99443.1 - 0.0058 16.2 0.3 0.38 10.4 0.2 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LuxS PF02664.10 EGF99443.1 - 0.14 11.6 0.2 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) DUF521 PF04412.8 EGF99444.1 - 0.14 10.7 0.2 0.2 10.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Mem_trans PF03547.13 EGF99447.1 - 0.17 10.1 1.1 0.2 9.8 0.8 1.1 1 0 0 1 1 1 0 Membrane transport protein zf-CCHC PF00098.18 EGF99448.1 - 0.00012 21.7 3.6 0.00019 21.2 2.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGF99448.1 - 0.032 13.8 0.9 0.056 13.1 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Zn_Tnp_IS91 PF14319.1 EGF99448.1 - 0.048 13.1 0.5 0.064 12.7 0.1 1.4 2 0 0 2 2 2 0 Transposase zinc-binding domain ThiF PF00899.16 EGF99449.1 - 1.4e-37 128.5 0.0 2.8e-37 127.5 0.0 1.5 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EGF99449.1 - 5e-23 80.4 0.3 9e-23 79.6 0.2 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 EGF99449.1 - 4e-19 68.1 0.4 7.1e-19 67.3 0.2 1.4 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 EGF99449.1 - 2.2e-17 62.1 2.4 2.2e-17 62.1 1.7 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 EGF99449.1 - 0.0014 18.1 0.6 0.008 15.7 0.0 2.2 2 0 0 2 2 2 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 EGF99449.1 - 0.006 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EGF99449.1 - 0.037 14.4 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.3 EGF99449.1 - 0.14 12.0 1.2 0.29 11.0 0.8 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein ADH_N PF08240.7 EGF99450.1 - 4e-20 71.5 2.5 7.4e-20 70.7 1.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGF99450.1 - 4.4e-12 45.6 0.0 8.5e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EGF99450.1 - 0.0086 15.6 0.0 0.016 14.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EGF99450.1 - 0.017 14.2 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EGF99450.1 - 0.07 12.6 0.1 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase KGG PF10685.4 EGF99451.1 - 8.2 6.4 15.6 5.6 7.0 1.0 3.4 3 0 0 3 3 3 0 Stress-induced bacterial acidophilic repeat motif CLASP_N PF12348.3 EGF99452.1 - 6.4e-68 228.5 0.3 1.7e-58 197.6 0.0 3.4 2 1 1 3 3 3 3 CLASP N terminal HEAT PF02985.17 EGF99452.1 - 1.3e-09 37.2 0.2 0.046 13.7 0.0 6.0 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 EGF99452.1 - 3.1e-05 24.1 5.3 0.18 12.0 0.5 5.4 3 2 2 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EGF99452.1 - 0.00058 20.2 4.1 2.9 8.4 0.0 5.3 4 1 1 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EGF99452.1 - 0.022 14.6 1.8 11 6.0 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion CMAS PF02353.15 EGF99453.1 - 1.1e-63 214.8 0.0 1.4e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGF99453.1 - 1.3e-10 41.1 0.0 3.6e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGF99453.1 - 8.7e-08 32.5 0.0 2.4e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGF99453.1 - 5.2e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGF99453.1 - 0.00011 22.7 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGF99453.1 - 0.00016 22.1 0.0 0.00028 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EGF99453.1 - 0.00024 20.4 0.0 0.00043 19.6 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 EGF99453.1 - 0.00039 19.8 0.0 0.00064 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGF99453.1 - 0.00086 19.6 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGF99453.1 - 0.001 19.0 0.0 0.0029 17.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Proteasome PF00227.21 EGF99454.1 - 1.1e-51 174.7 0.0 1.4e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGF99454.1 - 2e-14 52.5 0.0 3.9e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SNF5 PF04855.7 EGF99455.1 - 3e-50 170.9 2.2 5.8e-50 170.0 1.5 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Tyrosinase PF00264.15 EGF99458.1 - 2.8e-32 112.6 0.2 4.4e-32 112.0 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.15 EGF99459.1 - 2.7e-25 89.8 0.0 4.2e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase S4 PF01479.20 EGF99460.1 - 6e-10 38.4 0.0 1.1e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EGF99460.1 - 0.086 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 S4 domain EFP_N PF08207.7 EGF99462.1 - 0.1 12.4 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Snf7 PF03357.16 EGF99463.1 - 7.4e-41 139.3 17.2 7.4e-41 139.3 11.9 2.0 1 1 1 2 2 2 1 Snf7 COPR5 PF15340.1 EGF99463.1 - 0.48 10.7 3.8 0.79 10.0 0.3 2.4 1 1 0 2 2 2 0 Cooperator of PRMT5 family Atg14 PF10186.4 EGF99463.1 - 3 6.7 16.3 0.17 10.7 7.1 1.7 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2229 PF09989.4 EGF99463.1 - 9.3 5.6 6.8 5.9 6.2 1.9 2.1 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Ribosomal_L13 PF00572.13 EGF99464.1 - 1.5e-10 41.2 0.2 2.7e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 GTP_EFTU PF00009.22 EGF99465.1 - 3.9e-57 192.7 0.0 6.2e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGF99465.1 - 1.9e-36 124.2 0.0 5.7e-36 122.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGF99465.1 - 1.2e-18 66.9 1.5 4e-18 65.3 1.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EGF99465.1 - 1.9e-05 24.1 0.4 1.9e-05 24.1 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EGF99465.1 - 0.0015 18.4 0.2 0.0043 16.9 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_M16_C PF05193.16 EGF99466.1 - 6.9e-23 81.2 0.0 1.5e-11 44.3 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGF99466.1 - 2.8e-06 27.1 0.5 8.2e-06 25.6 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) PHD PF00628.24 EGF99467.1 - 2.5e-11 43.0 6.8 3e-11 42.8 3.7 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EGF99467.1 - 0.015 14.6 2.2 0.015 14.6 1.5 1.8 2 0 0 2 2 2 0 PHD-finger PHD_3 PF13922.1 EGF99467.1 - 0.019 15.2 0.5 0.063 13.5 0.4 1.9 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Kinesin PF00225.18 EGF99468.1 - 8.7e-103 343.5 1.1 1.1e-102 343.2 0.7 1.0 1 0 0 1 1 1 1 Kinesin motor domain CTD PF12815.2 EGF99469.1 - 0.0044 17.4 0.6 0.0058 17.0 0.4 1.3 1 0 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 SOBP PF15279.1 EGF99469.1 - 2.1 8.6 13.8 2.4 8.4 9.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein MoaE PF02391.12 EGF99471.1 - 4.1e-15 55.5 0.1 4.8e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Peptidase_M16_C PF05193.16 EGF99472.1 - 8.1e-23 81.0 0.0 2.2e-12 47.0 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGF99472.1 - 1.6e-06 27.9 0.6 4.7e-06 26.4 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Tim17 PF02466.14 EGF99473.1 - 1.3e-11 44.6 11.5 2.8e-11 43.5 8.0 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Aldo_ket_red PF00248.16 EGF99474.1 - 4e-62 209.6 0.0 5e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DeoC PF01791.4 EGF99475.1 - 8e-45 152.9 0.2 9.9e-45 152.6 0.1 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 EGF99475.1 - 0.0069 15.3 1.2 0.017 14.0 0.3 2.0 2 1 0 2 2 2 1 Dihydroorotate dehydrogenase Kinesin PF00225.18 EGF99476.1 - 3.4e-86 288.9 0.2 4.5e-86 288.5 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF4200 PF13863.1 EGF99476.1 - 0.0048 16.8 0.4 0.0048 16.8 0.3 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4200) FliD_N PF02465.13 EGF99476.1 - 0.21 11.9 3.6 0.91 9.9 1.0 2.6 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Peroxidase_2 PF01328.12 EGF99479.1 - 1.7e-11 43.3 0.1 2.8e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.12 EGF99480.1 - 9e-11 41.0 0.1 1.4e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.12 EGF99482.1 - 1.3e-09 37.1 0.0 2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 DNA_pol_phi PF04931.8 EGF99483.1 - 0.8 7.3 5.5 1.2 6.8 3.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_L13e PF01294.13 EGF99484.1 - 7.9e-61 204.6 5.0 1.1e-60 204.2 3.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Draxin PF15550.1 EGF99484.1 - 5.7 6.5 7.5 0.67 9.5 0.9 2.0 1 1 1 2 2 2 0 Draxin UEV PF05743.8 EGF99485.1 - 5.1e-37 126.2 0.0 8.3e-37 125.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EGF99485.1 - 1.1e-23 82.6 0.6 1.9e-23 81.8 0.4 1.4 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 EGF99485.1 - 0.0037 16.7 0.2 0.0085 15.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C2H2_2 PF12756.2 EGF99486.1 - 0.13 12.3 0.1 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.20 EGF99487.1 - 6.6e-30 104.1 0.0 8.9e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF99487.1 - 1.2e-18 67.1 0.0 1.6e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGF99487.1 - 0.035 13.0 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Baculo_PEP_C PF04513.7 EGF99489.1 - 0.049 13.4 0.2 0.12 12.1 0.2 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2360 PF10152.4 EGF99489.1 - 0.099 12.9 4.0 0.48 10.7 0.0 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) FCH PF00611.18 EGF99490.1 - 5.3e-14 52.1 0.2 5.3e-14 52.1 0.1 2.8 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DHC_N1 PF08385.7 EGF99490.1 - 0.00032 19.2 3.2 0.00055 18.4 2.2 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 CDP-OH_P_transf PF01066.16 EGF99491.1 - 4.9e-19 68.5 1.6 4.9e-19 68.5 1.1 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Mito_carr PF00153.22 EGF99492.1 - 1.2e-66 220.4 5.0 3.7e-24 84.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF46 PF01864.12 EGF99492.1 - 0.012 15.5 0.8 0.018 14.8 0.6 1.3 1 0 0 1 1 1 0 Putative integral membrane protein DUF46 UBN2 PF14223.1 EGF99495.1 - 3e-05 23.7 0.3 5.8e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGF99495.1 - 0.00041 19.8 0.6 0.00091 18.7 0.4 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EGF99495.1 - 0.0016 18.0 1.8 0.008 15.7 0.1 2.5 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type ADPrib_exo_Tox PF03496.9 EGF99495.1 - 0.0038 16.4 0.5 0.0068 15.6 0.3 1.3 1 0 0 1 1 1 1 ADP-ribosyltransferase exoenzyme DUF4447 PF14590.1 EGF99495.1 - 0.041 13.4 0.6 11 5.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4447) HTH_19 PF12844.2 EGF99495.1 - 0.064 13.3 0.8 0.19 11.7 0.1 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain 3-dmu-9_3-mt PF06983.8 EGF99496.1 - 0.0076 16.5 0.1 0.0091 16.3 0.0 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase BRCT PF00533.21 EGF99497.1 - 0.0066 16.5 0.1 0.034 14.2 0.1 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF4298 PF14131.1 EGF99497.1 - 0.079 12.8 0.1 0.33 10.8 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) AdoHcyase_NAD PF00670.16 EGF99497.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Arrestin_N PF00339.24 EGF99498.1 - 0.002 17.9 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain ADH_N PF08240.7 EGF99498.1 - 4.4 7.1 11.6 0.52 10.1 4.5 1.8 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain TrbI_Ftype PF09677.5 EGF99501.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) DUF1510 PF07423.6 EGF99502.1 - 0.0076 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF3446 PF11928.3 EGF99502.1 - 6.3 7.0 12.8 3 8.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Tht1 PF04163.7 EGF99505.1 - 1.4e-09 36.8 5.9 1.5e-08 33.4 4.1 2.0 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein TAN PF11640.3 EGF99505.1 - 0.011 15.4 0.5 0.032 13.9 0.1 1.9 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Baculo_PEP_C PF04513.7 EGF99505.1 - 0.35 10.6 7.6 1.7 8.4 0.1 3.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1212 PF06738.7 EGF99506.1 - 1.5e-23 83.3 1.7 1.5e-23 83.3 1.2 2.8 3 1 1 4 4 4 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EGF99506.1 - 3.6e-13 49.5 6.4 3.6e-13 49.5 4.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) DUF2301 PF10063.4 EGF99506.1 - 0.24 11.6 5.4 0.53 10.4 3.8 1.6 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) DUF4524 PF15025.1 EGF99507.1 - 0.072 12.5 0.2 0.081 12.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) MRP-L27 PF09809.4 EGF99509.1 - 6.9e-07 28.8 0.3 1.3e-05 24.7 0.1 2.3 2 1 0 2 2 2 1 Mitochondrial ribosomal protein L27 KH_1 PF00013.24 EGF99514.1 - 1.3e-41 139.9 15.0 1.8e-16 59.5 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGF99514.1 - 4e-32 109.3 15.5 1.6e-11 43.5 1.1 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EGF99514.1 - 8.5e-12 44.4 11.6 0.0039 16.7 0.7 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.1 EGF99514.1 - 8.7e-09 34.9 1.6 0.054 13.1 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EGF99514.1 - 0.00088 19.0 6.5 0.87 9.4 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain CSD PF00313.17 EGF99515.1 - 1.6e-12 46.9 0.1 1e-11 44.4 0.1 2.0 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain WLM PF08325.5 EGF99517.1 - 4.8e-25 88.5 0.1 1.1e-24 87.3 0.0 1.6 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.4 EGF99517.1 - 0.081 12.5 0.2 0.081 12.5 0.2 1.6 2 0 0 2 2 2 0 SprT-like family Hexapep_2 PF14602.1 EGF99518.1 - 3.2 7.3 8.6 3.4 7.3 2.2 3.0 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase SEP PF08059.8 EGF99520.1 - 1.8e-24 85.7 0.0 5.2e-24 84.3 0.0 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 EGF99520.1 - 3.3e-13 49.4 0.0 5.8e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EGF99520.1 - 6.5e-12 44.7 0.1 1.2e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain TRAPPC10 PF12584.3 EGF99522.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 Snapin_Pallidin PF14712.1 EGF99522.1 - 0.1 12.9 1.3 1.1 9.5 0.3 2.6 2 0 0 2 2 2 0 Snapin/Pallidin DUF3596 PF12167.3 EGF99523.1 - 0.1 12.1 1.3 0.34 10.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) FmdA_AmdA PF03069.10 EGF99523.1 - 0.12 11.0 0.0 1.3 7.6 0.1 2.0 2 0 0 2 2 2 0 Acetamidase/Formamidase family CDC45 PF02724.9 EGF99523.1 - 0.24 9.3 6.1 0.41 8.6 4.2 1.5 1 0 0 1 1 1 0 CDC45-like protein Rab5ip PF07019.7 EGF99524.1 - 2.7e-16 59.4 9.9 4e-16 58.9 6.8 1.3 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Peptidase_U4 PF03419.8 EGF99524.1 - 0.32 10.0 4.2 0.42 9.6 2.9 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Tic20 PF09685.5 EGF99524.1 - 0.6 10.1 5.1 0.82 9.6 3.5 1.3 1 0 0 1 1 1 0 Tic20-like protein zf-DHHC PF01529.15 EGF99524.1 - 5.4 6.3 7.1 7.6 5.8 4.9 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase LSM PF01423.17 EGF99525.1 - 5.6e-17 61.0 0.1 6.1e-17 60.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain Cutinase PF01083.17 EGF99528.1 - 5.9e-29 101.0 4.4 7.9e-29 100.6 3.1 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 EGF99528.1 - 0.047 13.5 0.1 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 EGF99528.1 - 0.072 12.5 0.1 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain VRR_NUC PF08774.6 EGF99529.1 - 0.86 9.6 5.0 5.4 7.0 0.1 2.7 2 1 1 3 3 3 0 VRR-NUC domain DUF2034 PF10356.4 EGF99530.1 - 6.2e-13 48.3 0.0 4.8e-06 25.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EGF99530.1 - 0.0051 16.6 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease RPEL PF02755.10 EGF99534.1 - 0.31 10.4 1.3 1 8.7 0.0 2.3 2 0 0 2 2 2 0 RPEL repeat PEX11 PF05648.9 EGF99538.1 - 3.2e-07 29.8 0.4 1.6e-06 27.5 0.3 1.9 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Prefoldin_2 PF01920.15 EGF99539.1 - 0.048 13.4 0.9 0.048 13.4 0.6 3.0 3 1 1 4 4 4 0 Prefoldin subunit FemAB PF02388.11 EGF99539.1 - 0.09 11.4 0.3 0.24 10.0 0.1 1.7 2 0 0 2 2 2 0 FemAB family SlyX PF04102.7 EGF99539.1 - 0.19 12.1 4.3 0.72 10.2 3.0 2.1 1 0 0 1 1 1 0 SlyX SUZ PF12752.2 EGF99539.1 - 3.7 8.1 6.1 4.2 7.9 1.6 2.9 2 1 0 2 2 2 0 SUZ domain DUF2318 PF10080.4 EGF99542.1 - 0.034 13.9 0.7 0.034 13.9 0.5 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) ABC_tran_2 PF12848.2 EGF99542.1 - 0.095 12.5 0.5 0.18 11.6 0.3 1.3 1 0 0 1 1 1 0 ABC transporter HypA PF01155.14 EGF99542.1 - 9.7 5.9 8.0 0.61 9.7 0.4 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF4451 PF14616.1 EGF99543.1 - 3.2e-13 49.5 3.0 7.1e-13 48.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) FAR1 PF03101.10 EGF99544.1 - 0.076 13.5 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain Asp PF00026.18 EGF99545.1 - 4.6e-10 39.2 0.7 8.9e-08 31.7 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGF99545.1 - 0.17 11.8 0.1 2 8.3 0.0 2.4 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal DUF3402 PF11882.3 EGF99548.1 - 1.3e-127 426.3 2.6 1.9e-126 422.4 1.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EGF99548.1 - 3e-44 151.0 0.0 1.2e-43 149.1 0.0 1.9 1 1 0 1 1 1 1 N1221-like protein GCP5-Mod21 PF14609.1 EGF99548.1 - 0.027 12.5 1.1 0.043 11.9 0.8 1.2 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Ras PF00071.17 EGF99549.1 - 1.6e-55 186.9 0.0 1.8e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGF99549.1 - 1.1e-15 58.2 0.0 1.5e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGF99549.1 - 5.9e-07 28.8 0.0 9.3e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGF99549.1 - 0.0062 15.7 0.0 0.008 15.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGF99549.1 - 0.043 12.9 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Nipped-B_C PF12830.2 EGF99550.1 - 3.6e-42 144.1 0.1 1.1e-41 142.4 0.0 2.0 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus IBN_N PF03810.14 EGF99551.1 - 3.7e-13 49.1 0.1 6.6e-13 48.3 0.0 1.5 1 1 1 2 2 2 2 Importin-beta N-terminal domain HEAT_2 PF13646.1 EGF99551.1 - 0.11 12.8 0.2 0.18 12.1 0.2 1.4 1 1 0 1 1 1 0 HEAT repeats HEAT_2 PF13646.1 EGF99552.1 - 0.0051 17.0 0.0 0.02 15.1 0.0 2.0 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.17 EGF99552.1 - 0.034 14.2 0.0 0.2 11.8 0.0 2.4 1 0 0 1 1 1 0 HEAT repeat Pox_Ag35 PF03286.9 EGF99552.1 - 5 6.6 6.5 0.38 10.2 0.1 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SAC3_GANP PF03399.11 EGF99553.1 - 2.3e-06 27.2 0.9 2.3e-06 27.2 0.6 1.5 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DERM PF14704.1 EGF99553.1 - 0.042 13.8 0.8 0.28 11.1 0.2 2.2 2 0 0 2 2 2 0 Dermatopontin Peroxidase_2 PF01328.12 EGF99554.1 - 5.3e-11 41.7 0.1 1.8e-10 40.0 0.1 1.8 1 1 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.12 EGF99555.1 - 5.7e-11 41.6 0.2 3.6e-10 39.0 0.2 2.0 1 1 0 1 1 1 1 Peroxidase, family 2 TAXi_N PF14543.1 EGF99555.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal UPF0016 PF01169.14 EGF99556.1 - 3e-43 145.8 20.9 6.2e-23 80.7 5.6 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 G3P_acyltransf PF02660.10 EGF99556.1 - 0.01 15.3 5.1 0.01 15.3 3.5 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase Pkinase PF00069.20 EGF99557.1 - 9.9e-67 224.8 0.0 1.1e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF99557.1 - 1.4e-40 139.0 0.0 1.6e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGF99557.1 - 0.00023 20.9 0.0 0.055 13.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGF99557.1 - 0.089 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ZYG-11_interact PF05884.7 EGF99560.1 - 0.6 9.1 2.9 0.8 8.7 2.0 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF3628 PF12300.3 EGF99561.1 - 0.14 12.2 4.5 0.15 12.0 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) RNA_pol_Rpb2_5 PF04567.12 EGF99564.1 - 0.029 14.3 0.3 0.05 13.5 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Lysis_col PF02402.11 EGF99566.1 - 0.048 13.2 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 Lysis protein MBOAT_2 PF13813.1 EGF99567.1 - 1.8e-13 50.3 3.8 4.5e-13 49.0 2.3 2.0 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family Oligomerisation PF02410.10 EGF99568.1 - 5.2e-12 45.6 0.0 8.3e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Oligomerisation domain CTF_NFI PF00859.13 EGF99569.1 - 0.1 12.3 2.0 0.15 11.7 1.4 1.5 1 1 0 1 1 1 0 CTF/NF-I family transcription modulation region Lipase_GDSL PF00657.17 EGF99570.1 - 1.2e-07 31.8 0.1 1.5e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EGF99570.1 - 0.00088 19.4 0.1 0.0012 19.0 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AFT PF08731.6 EGF99571.1 - 0.00039 20.5 0.9 0.0011 19.0 0.6 1.8 1 1 0 1 1 1 1 Transcription factor AFT SID-1_RNA_chan PF13965.1 EGF99572.1 - 0.12 10.4 0.3 0.14 10.2 0.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Vfa1 PF08432.5 EGF99572.1 - 0.5 10.3 5.8 0.62 10.0 4.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Prefoldin PF02996.12 EGF99574.1 - 0.025 14.1 2.7 0.3 10.7 0.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit Coatomer_E PF04733.9 EGF99574.1 - 0.15 11.2 3.5 5 6.2 0.3 2.1 2 0 0 2 2 2 0 Coatomer epsilon subunit Exonuc_VII_L PF02601.10 EGF99574.1 - 0.25 10.5 4.1 0.27 10.3 2.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3263 PF11662.3 EGF99574.1 - 0.5 9.8 8.9 0.063 12.7 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) YolD PF08863.5 EGF99574.1 - 0.83 9.5 5.2 0.38 10.6 0.1 2.4 2 1 1 3 3 3 0 YolD-like protein Fmp27_WPPW PF10359.4 EGF99574.1 - 1.8 6.8 8.0 2 6.7 5.5 1.3 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain EMP24_GP25L PF01105.19 EGF99574.1 - 2.5 7.8 7.9 0.87 9.2 1.9 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Seryl_tRNA_N PF02403.17 EGF99574.1 - 3.6 7.6 11.0 0.058 13.4 1.9 2.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Muted PF14942.1 EGF99574.1 - 4.3 7.2 12.5 2.7 7.8 5.8 2.3 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein DUF4611 PF15387.1 EGF99576.1 - 0.21 11.7 3.1 0.36 11.0 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Phosducin PF02114.11 EGF99577.1 - 1.6e-07 30.3 0.2 1.9e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EGF99577.1 - 1.6e-05 24.5 0.0 3.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.11 EGF99577.1 - 0.0096 15.4 0.3 0.014 14.8 0.2 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 Spt5_N PF11942.3 EGF99577.1 - 0.39 11.3 9.9 0.65 10.6 6.9 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal tRNA-synt_2 PF00152.15 EGF99578.1 - 9.3e-80 267.9 0.0 1.7e-79 267.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGF99578.1 - 2.6e-06 27.2 0.1 4.6e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Lipase_GDSL PF00657.17 EGF99581.1 - 0.085 12.6 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Tyr-DNA_phospho PF06087.7 EGF99582.1 - 9.2e-07 27.8 0.0 1.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Fork_head PF00250.13 EGF99584.1 - 2.2e-15 56.4 0.0 2.3e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Fork head domain HARE-HTH PF05066.8 EGF99584.1 - 0.0092 16.3 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain AA_permease_2 PF13520.1 EGF99585.1 - 1.8e-55 188.2 47.9 2.1e-55 187.9 33.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGF99585.1 - 2.9e-14 52.2 37.7 4e-14 51.8 26.1 1.1 1 0 0 1 1 1 1 Amino acid permease GHMP_kinases_C PF08544.8 EGF99586.1 - 1.2e-11 44.6 0.0 2.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EGF99586.1 - 5.7e-10 39.1 0.0 1.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain DnaJ PF00226.26 EGF99589.1 - 4.8e-19 67.8 0.0 2.7e-18 65.4 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EGF99589.1 - 1.2e-11 44.0 6.3 2e-09 36.9 0.2 3.5 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 EGF99589.1 - 5e-08 32.2 0.4 0.016 15.1 0.1 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGF99589.1 - 3e-06 26.5 2.9 0.48 10.1 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGF99589.1 - 0.0012 18.7 0.4 0.0012 18.7 0.3 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGF99589.1 - 0.0026 18.2 1.9 25 5.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGF99589.1 - 0.014 16.0 2.5 0.21 12.3 0.5 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGF99589.1 - 0.066 13.6 2.7 1 9.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGF99589.1 - 0.23 11.8 5.0 0.34 11.2 0.2 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.2 EGF99593.1 - 0.0015 18.1 0.0 0.0037 16.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGF99593.1 - 0.015 14.9 1.7 0.015 14.9 1.2 2.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGF99593.1 - 0.57 9.9 7.1 0.14 11.9 1.6 2.3 2 0 0 2 2 2 0 Leucine rich repeat zf-CCHC_6 PF15288.1 EGF99594.1 - 0.11 12.1 6.2 0.067 12.8 2.6 1.8 2 0 0 2 2 2 0 Zinc knuckle PBP1_TM PF14812.1 EGF99597.1 - 3.7 7.9 6.4 11 6.4 4.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tctex-1 PF03645.8 EGF99599.1 - 0.0017 18.1 0.1 0.0025 17.6 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family His_biosynth PF00977.16 EGF99601.1 - 8.2e-29 100.4 0.0 1.1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Sod_Fe_C PF02777.13 EGF99602.1 - 4.9e-14 52.0 0.0 3.7e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain adh_short PF00106.20 EGF99603.1 - 4.5e-27 94.9 0.1 9.5e-27 93.9 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGF99603.1 - 1.4e-12 47.6 0.3 6.1e-12 45.5 0.2 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGF99603.1 - 1.5e-08 34.7 0.0 2.1e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGF99603.1 - 0.00021 20.7 0.0 0.00039 19.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGF99603.1 - 0.002 18.1 0.0 0.0066 16.4 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGF99603.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 EGF99603.1 - 0.04 12.6 0.0 0.058 12.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Endonuclease_7 PF02945.10 EGF99603.1 - 0.094 12.4 0.2 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Recombination endonuclease VII RIO1 PF01163.17 EGF99605.1 - 1.8e-11 43.7 0.1 2.1e-11 43.5 0.0 1.3 1 1 0 1 1 1 1 RIO1 family EcKinase PF02958.15 EGF99605.1 - 0.022 13.9 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.9 EGF99605.1 - 0.036 13.1 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.2 EGF99607.1 - 0.0064 16.0 0.5 0.03 13.9 0.4 2.1 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EGF99607.1 - 0.013 15.1 0.4 0.048 13.3 0.3 2.1 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EGF99607.1 - 0.054 13.1 2.4 0.79 9.4 0.1 2.9 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.1 EGF99607.1 - 0.26 11.0 2.9 1.1 9.0 1.0 2.5 2 0 0 2 2 2 0 Leucine rich repeat PIN_4 PF13638.1 EGF99609.1 - 3.7e-13 49.7 0.0 8.8e-13 48.5 0.0 1.6 1 1 0 1 1 1 1 PIN domain Pkr1 PF08636.5 EGF99611.1 - 1.2e-14 54.0 2.7 1.6e-14 53.7 1.9 1.2 1 0 0 1 1 1 1 ER protein Pkr1 DUF3796 PF12676.2 EGF99611.1 - 0.0051 17.0 0.6 0.0067 16.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3796) UbiA PF01040.13 EGF99611.1 - 0.0085 15.3 1.8 0.011 15.0 1.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4131 PF13567.1 EGF99611.1 - 0.089 12.1 0.2 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pescadillo_N PF06732.6 EGF99612.1 - 9.6e-115 382.6 0.1 9.6e-115 382.6 0.1 2.3 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 EGF99612.1 - 1.1e-11 44.6 0.0 8.1e-11 41.9 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Myc_N PF01056.13 EGF99612.1 - 0.0094 15.1 2.3 0.0094 15.1 1.6 2.1 3 0 0 3 3 3 1 Myc amino-terminal region EBV-NA3 PF05009.7 EGF99612.1 - 0.22 10.7 3.5 0.5 9.5 2.4 1.6 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) AD PF09793.4 EGF99613.1 - 8e-19 67.2 0.0 1.9e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain RHIM PF12721.2 EGF99613.1 - 0.005 17.2 0.0 0.005 17.2 0.0 3.8 3 1 0 3 3 3 1 RIP homotypic interaction motif RNA_POL_M_15KD PF02150.11 EGF99614.1 - 1e-11 44.3 1.0 1e-11 44.3 0.7 2.5 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 EGF99614.1 - 1.7e-10 40.3 2.9 1.7e-10 40.3 2.0 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 EGF99614.1 - 0.0053 17.0 4.9 0.0053 17.0 0.1 2.3 2 1 0 2 2 2 1 Restriction alleviation protein Lar Elf1 PF05129.8 EGF99614.1 - 0.0066 16.1 1.6 0.1 12.2 0.1 2.2 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like DUF3268 PF11672.3 EGF99614.1 - 0.033 14.2 4.0 0.24 11.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Zn_ribbon_recom PF13408.1 EGF99614.1 - 0.045 14.0 1.4 2.9 8.2 0.1 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.5 EGF99614.1 - 0.057 13.3 6.3 13 5.8 0.0 3.8 4 0 0 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EGF99614.1 - 0.06 13.1 1.1 0.06 13.1 0.7 2.5 2 2 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 EGF99614.1 - 0.12 12.2 7.1 3.6 7.4 0.2 2.9 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1 PF03811.8 EGF99614.1 - 0.26 10.8 0.0 0.26 10.8 0.0 3.4 4 0 0 4 4 4 0 InsA N-terminal domain C1_4 PF07975.7 EGF99614.1 - 0.45 10.5 9.4 3 7.9 0.4 2.9 2 1 1 3 3 3 0 TFIIH C1-like domain DUF3795 PF12675.2 EGF99614.1 - 0.47 10.6 4.1 2.4 8.3 1.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) TF_Zn_Ribbon PF08271.7 EGF99614.1 - 0.89 8.9 8.5 0.078 12.3 1.0 2.7 3 1 0 3 3 3 0 TFIIB zinc-binding Thioredoxin_2 PF13098.1 EGF99614.1 - 0.91 9.7 3.6 0.72 10.0 0.3 2.0 1 1 1 2 2 2 0 Thioredoxin-like domain DNA_RNApol_7kD PF03604.8 EGF99614.1 - 0.98 8.9 8.1 9.5 5.7 0.1 3.8 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Dynactin_p62 PF05502.8 EGF99614.1 - 2.1 7.0 6.5 0.22 10.2 0.5 1.8 2 0 0 2 2 2 0 Dynactin p62 family zf-piccolo PF05715.8 EGF99614.1 - 2.2 8.3 5.0 0.44 10.5 0.6 1.8 2 0 0 2 2 2 0 Piccolo Zn-finger zf-IS66 PF13005.2 EGF99614.1 - 4.1 7.4 9.0 7.9 6.5 0.3 3.5 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 PHD PF00628.24 EGF99614.1 - 7.7 6.3 7.6 14 5.5 0.6 2.8 2 2 0 2 2 2 0 PHD-finger eRF1_1 PF03463.10 EGF99615.1 - 7.4e-36 122.6 0.0 1.4e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EGF99615.1 - 1.2e-20 73.8 0.0 2.6e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EGF99615.1 - 2.1e-17 63.6 0.0 3.3e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Tet_JBP PF12851.2 EGF99617.1 - 0.00029 20.1 0.0 0.00051 19.3 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily EMP24_GP25L PF01105.19 EGF99618.1 - 1.4e-18 67.2 0.1 1.5e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD JmjC PF02373.17 EGF99620.1 - 1.1e-12 48.2 0.7 4.7e-12 46.1 0.1 2.4 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EGF99620.1 - 0.00079 18.9 0.1 0.29 10.5 0.0 2.6 2 0 0 2 2 2 2 Cupin-like domain PepSY_TM_2 PF13703.1 EGF99621.1 - 1.4 9.1 4.1 5 7.3 0.2 2.2 2 0 0 2 2 2 0 PepSY-associated TM helix DUF3584 PF12128.3 EGF99623.1 - 0.015 12.6 19.9 0.018 12.4 13.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3391 PF11871.3 EGF99623.1 - 0.018 15.2 6.2 0.61 10.3 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF1664 PF07889.7 EGF99623.1 - 0.026 14.3 6.4 11 5.8 0.1 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) P22_AR_C PF10548.4 EGF99623.1 - 0.067 13.0 0.5 0.26 11.2 0.0 2.3 3 0 0 3 3 3 0 P22AR C-terminal domain Sod_Ni PF09055.6 EGF99623.1 - 0.12 12.7 3.2 6.1 7.2 0.0 2.9 2 1 1 3 3 3 0 Nickel-containing superoxide dismutase Alg14 PF08660.6 EGF99623.1 - 0.17 11.8 0.7 4.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like Sec8_exocyst PF04048.9 EGF99623.1 - 0.66 9.6 10.2 3.4 7.2 0.1 3.5 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain DUF2762 PF10960.3 EGF99623.1 - 0.73 9.5 5.6 6.1 6.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) DUF883 PF05957.8 EGF99623.1 - 0.89 9.9 15.2 2.2 8.7 1.4 3.5 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) IF-2B PF01008.12 EGF99623.1 - 1.1 8.2 4.6 3.7 6.4 3.2 1.9 1 1 0 1 1 1 0 Initiation factor 2 subunit family DUF2935 PF11155.3 EGF99623.1 - 1.3 9.1 6.6 6.3 6.9 3.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) HSP33 PF01430.14 EGF99623.1 - 2.6 7.0 12.0 2.7 7.0 1.6 2.3 2 0 0 2 2 2 0 Hsp33 protein DUF4315 PF14193.1 EGF99623.1 - 3.7 7.5 10.1 0.53 10.2 2.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) Pkinase PF00069.20 EGF99624.1 - 2.6e-15 56.3 0.0 3.3e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF99624.1 - 2.1e-10 40.0 0.0 2.7e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4218 PF13960.1 EGF99627.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) DUF947 PF06102.7 EGF99628.1 - 0.013 15.3 1.8 0.024 14.4 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF947) FliG_N PF14842.1 EGF99628.1 - 0.013 15.5 0.5 0.028 14.5 0.4 1.6 1 0 0 1 1 1 0 FliG N-terminal domain Imm24 PF15570.1 EGF99628.1 - 0.015 15.0 1.5 0.057 13.1 0.4 2.2 2 0 0 2 2 2 0 Immunity protein 24 DUF3106 PF11304.3 EGF99628.1 - 0.18 12.2 1.7 0.3 11.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) DUF842 PF05811.8 EGF99629.1 - 0.13 11.6 6.7 2.2 7.7 0.2 2.7 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DUF778 PF05608.7 EGF99629.1 - 0.38 10.6 2.1 0.73 9.7 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF778) bZIP_2 PF07716.10 EGF99629.1 - 0.57 10.0 12.3 1.8 8.4 1.0 3.3 3 0 0 3 3 3 0 Basic region leucine zipper DUF16 PF01519.11 EGF99629.1 - 0.68 10.1 6.9 1.4 9.2 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 Reo_sigmaC PF04582.7 EGF99629.1 - 0.69 9.0 12.6 0.87 8.6 1.8 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Ribosomal_S30AE PF02482.14 EGF99629.1 - 0.73 10.3 4.6 6.6 7.2 0.5 2.9 1 1 2 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF4140 PF13600.1 EGF99629.1 - 0.8 10.1 6.9 4.7 7.7 1.1 3.4 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) H-kinase_dim PF02895.9 EGF99629.1 - 1.2 9.5 14.9 2.4 8.5 7.0 3.1 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DUF1664 PF07889.7 EGF99629.1 - 2 8.2 12.1 3.4 7.4 0.9 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF745 PF05335.8 EGF99629.1 - 3.4 7.1 10.1 2.2 7.7 1.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF745) LXG PF04740.7 EGF99629.1 - 4.2 7.1 13.4 6.9 6.4 2.0 2.8 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF1664 PF07889.7 EGF99630.1 - 0.25 11.1 4.1 0.5 10.1 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2458 PF10454.4 EGF99630.1 - 0.84 9.5 13.0 1.2 9.0 2.4 3.7 3 2 1 4 4 4 0 Protein of unknown function (DUF2458) KxDL PF10241.4 EGF99630.1 - 1.3 9.0 12.4 0.6 10.0 3.1 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein Nsp1_C PF05064.8 EGF99630.1 - 7.2 6.2 11.5 7.7 6.1 4.5 2.7 1 1 1 2 2 2 0 Nsp1-like C-terminal region TMEM238 PF15125.1 EGF99631.1 - 0.33 10.8 1.9 0.67 9.9 1.3 1.4 1 0 0 1 1 1 0 TMEM238 protein family DUF3818 PF12825.2 EGF99633.1 - 4.7e-49 166.8 6.9 1.5e-43 148.8 5.1 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EGF99633.1 - 1.5e-05 24.6 0.0 5.7e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 PX-associated HTH_38 PF13936.1 EGF99633.1 - 0.0014 18.1 0.1 0.005 16.3 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EGF99633.1 - 0.021 14.4 0.6 0.08 12.6 0.4 1.9 1 0 0 1 1 1 0 Homeodomain-like domain Chitin_synth_1 PF01644.12 EGF99634.1 - 6.4e-57 191.9 0.0 1.1e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGF99634.1 - 1.6e-25 88.6 0.0 2.9e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGF99634.1 - 3e-23 82.0 0.0 5.2e-20 71.3 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EGF99634.1 - 1.6e-11 44.2 0.1 1.6e-11 44.2 0.1 2.6 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGF99634.1 - 6.8e-07 29.3 0.0 1.8e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 E2_bind PF08825.5 EGF99635.1 - 0.052 13.2 0.4 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 E2 binding domain SNase PF00565.12 EGF99636.1 - 6.4e-57 190.4 0.0 7.1e-21 74.4 0.0 7.0 5 2 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EGF99636.1 - 1.7e-20 73.0 0.0 3.2e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 EGF99636.1 - 0.00018 20.7 0.0 0.00039 19.6 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF3818 PF12825.2 EGF99637.1 - 2.4e-48 164.5 4.8 1.4e-47 162.0 2.7 2.3 1 1 1 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EGF99637.1 - 2.8e-19 69.0 0.7 1.4e-18 66.7 0.5 2.2 1 1 0 1 1 1 1 PX-associated Pox_A3L PF05288.6 EGF99637.1 - 0.065 12.9 2.5 1.8 8.3 0.0 3.2 3 0 0 3 3 3 0 Poxvirus A3L Protein DUF2962 PF11176.3 EGF99639.1 - 1.9e-32 111.9 0.6 2.4e-32 111.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Ribosomal_S17e PF00833.13 EGF99639.1 - 0.13 12.0 0.1 0.13 12.0 0.1 2.0 3 0 0 3 3 3 0 Ribosomal S17 PHP PF02811.14 EGF99640.1 - 2.7e-12 46.8 0.0 3.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 PHP domain TPR_11 PF13414.1 EGF99641.1 - 3e-12 45.9 1.3 3.4e-08 33.0 0.0 2.4 1 1 1 2 2 2 2 TPR repeat F-box-like PF12937.2 EGF99641.1 - 1.5e-08 34.2 0.5 3.4e-08 33.0 0.4 1.7 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.12 EGF99641.1 - 2.2e-07 30.2 0.2 0.031 14.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGF99641.1 - 3.6e-07 29.5 0.3 0.32 10.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat F-box PF00646.28 EGF99641.1 - 2.9e-06 26.7 0.8 9.8e-06 25.0 0.1 2.2 2 0 0 2 2 2 1 F-box domain TPR_12 PF13424.1 EGF99641.1 - 0.00057 19.7 0.7 0.2 11.6 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGF99641.1 - 0.0055 17.2 0.1 3.8 8.3 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGF99641.1 - 0.0063 17.1 0.1 0.24 12.1 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGF99641.1 - 0.051 13.4 0.0 0.65 9.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGF99641.1 - 0.096 13.1 0.5 18 6.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3885 PF13021.1 EGF99642.1 - 0.097 12.3 0.3 2.9 7.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) DUF563 PF04577.9 EGF99643.1 - 6.2e-17 62.2 0.0 9.8e-17 61.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF563) SKN1 PF03935.10 EGF99644.1 - 5.8e-191 635.0 6.5 6.5e-191 634.8 4.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GAS2 PF02187.12 EGF99645.1 - 2.1e-05 24.1 0.3 6e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Herpes_BLLF1 PF05109.8 EGF99646.1 - 0.041 11.8 2.6 0.041 11.8 1.8 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SH2_2 PF14633.1 EGF99647.1 - 8.3e-74 247.3 0.2 8.3e-74 247.3 0.1 1.6 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.1 EGF99647.1 - 2.5e-34 117.5 0.2 7.2e-34 116.0 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif DLD PF14878.1 EGF99647.1 - 8e-31 106.5 0.6 8e-31 106.5 0.4 3.4 3 1 1 4 4 4 1 Death-like domain of SPT6 YqgF PF14639.1 EGF99647.1 - 5.2e-23 81.2 0.0 3.8e-22 78.4 0.0 2.4 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.1 EGF99647.1 - 5.6e-18 65.0 2.2 7.8e-18 64.6 0.4 2.1 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 EGF99647.1 - 3.8e-13 49.3 54.9 1.7e-12 47.3 23.7 4.4 3 1 0 3 3 3 2 Acidic N-terminal SPT6 SH2 PF00017.19 EGF99647.1 - 1.6e-06 27.7 0.0 5.4e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 EGF99647.1 - 5.1e-05 23.1 0.0 0.00022 21.0 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF3981 PF13139.1 EGF99648.1 - 0.082 12.9 1.5 0.28 11.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) NdhN PF11909.3 EGF99648.1 - 0.14 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N HMG_box PF00505.14 EGF99649.1 - 6.3e-13 48.7 1.5 6.3e-13 48.7 1.0 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGF99649.1 - 0.00096 19.4 0.2 0.0024 18.1 0.1 1.7 1 0 0 1 1 1 1 HMG-box domain zf-RING_UBOX PF13445.1 EGF99650.1 - 1.4e-17 63.1 8.6 2.2e-17 62.4 0.5 2.9 3 0 0 3 3 3 1 RING-type zinc-finger CLTH PF10607.4 EGF99650.1 - 1.2e-15 57.4 0.1 8.4e-15 54.7 0.0 2.1 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Rtf2 PF04641.7 EGF99650.1 - 3.9e-05 22.9 0.0 8.2e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.1 EGF99650.1 - 0.00042 19.9 2.5 0.012 15.3 0.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGF99650.1 - 0.0016 18.0 1.6 0.0034 17.0 0.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AalphaY_MDB PF04611.7 EGF99650.1 - 0.0026 17.6 0.1 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 Mating type protein A alpha Y mating type dependent binding region zf-RING_2 PF13639.1 EGF99650.1 - 0.0053 16.5 1.2 0.01 15.6 0.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGF99650.1 - 0.012 15.5 4.3 0.014 15.4 0.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FCD PF07729.7 EGF99650.1 - 0.026 14.8 0.1 0.097 12.9 0.0 2.0 1 0 0 1 1 1 0 FCD domain Ribosomal_L50 PF10501.4 EGF99650.1 - 0.029 14.3 0.0 0.097 12.6 0.0 1.9 1 0 0 1 1 1 0 Ribosomal subunit 39S zf-C3HC4 PF00097.20 EGF99650.1 - 0.03 13.9 0.5 0.03 13.9 0.3 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGF99650.1 - 0.88 9.5 4.6 0.25 11.2 0.6 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TBPIP PF07106.8 EGF99650.1 - 2 7.9 5.8 4.1 6.9 4.0 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-Nse PF11789.3 EGF99650.1 - 2.3 7.7 4.7 1.1 8.8 0.8 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Histone PF00125.19 EGF99652.1 - 4.1e-14 52.4 0.1 5e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGF99652.1 - 3.8e-05 23.7 0.0 5e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EGF99652.1 - 0.00011 22.0 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EGF99652.1 - 0.0013 18.7 0.1 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGF99652.1 - 0.047 12.9 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2491 PF10679.4 EGF99653.1 - 0.055 12.4 0.5 0.08 11.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Cu-oxidase_2 PF07731.9 EGF99654.1 - 0.071 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Multicopper oxidase Arylesterase PF01731.15 EGF99654.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Arylesterase YvbH_ext PF11724.3 EGF99656.1 - 0.023 14.3 0.0 0.086 12.5 0.0 2.0 1 0 0 1 1 1 0 YvbH-like oligomerisation region RhoGAP PF00620.22 EGF99657.1 - 0.00054 19.5 0.0 0.00055 19.5 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain DUF1952 PF09189.5 EGF99657.1 - 0.069 12.8 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) S1 PF00575.18 EGF99658.1 - 2.6e-39 133.1 9.6 1e-12 47.9 0.0 10.4 11 1 0 11 11 11 4 S1 RNA binding domain TPR_16 PF13432.1 EGF99658.1 - 2.8e-10 40.5 0.0 0.0007 20.2 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGF99658.1 - 9.3e-10 38.7 0.0 0.013 15.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGF99658.1 - 3.6e-07 30.2 0.0 0.014 15.9 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGF99658.1 - 4.7e-05 22.9 0.0 0.049 13.2 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_6 PF13174.1 EGF99658.1 - 7.4e-05 22.9 0.1 0.049 14.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EGF99658.1 - 0.00047 20.2 0.6 0.0057 16.7 0.3 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGF99658.1 - 0.00053 19.8 1.8 0.51 10.3 0.0 3.4 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGF99658.1 - 0.0058 16.3 0.1 0.12 12.2 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGF99658.1 - 0.006 15.6 2.7 0.027 13.5 1.6 2.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGF99658.1 - 0.025 14.4 0.0 0.87 9.6 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Suf PF05843.9 EGF99658.1 - 0.053 13.2 12.4 0.23 11.1 0.8 3.4 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) Methyltransf_26 PF13659.1 EGF99660.1 - 3.1e-13 49.7 0.0 4.3e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGF99660.1 - 1e-10 41.2 0.0 1.9e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EGF99660.1 - 0.00024 20.7 0.0 0.00031 20.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGF99660.1 - 0.004 17.4 0.0 0.007 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EGF99660.1 - 0.041 13.4 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 EGF99660.1 - 0.044 14.2 0.0 0.083 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EGF99660.1 - 0.089 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_transf_90 PF05686.7 EGF99663.1 - 6.6e-08 31.6 0.3 0.0015 17.2 0.0 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 TMEM154 PF15102.1 EGF99663.1 - 0.11 12.2 2.2 0.23 11.1 1.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family SSP160 PF06933.6 EGF99663.1 - 9.7 4.0 8.5 14 3.4 5.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DnaJ PF00226.26 EGF99665.1 - 2.7e-10 39.8 0.3 8.9e-10 38.1 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.1 EGF99665.1 - 3.5e-06 27.2 0.1 0.042 14.1 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGF99665.1 - 3.8e-06 26.4 0.1 0.0028 17.2 0.0 2.6 2 0 0 2 2 2 2 TPR repeat Apc3 PF12895.2 EGF99665.1 - 0.00026 21.0 3.1 0.0015 18.6 0.1 3.0 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGF99665.1 - 0.00069 20.0 0.0 9.1 7.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGF99665.1 - 0.0048 17.5 0.5 1.6 9.4 0.0 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGF99665.1 - 0.0085 15.9 0.4 7 6.8 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF309 PF03745.9 EGF99665.1 - 0.023 14.1 0.1 0.052 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF309) MDFI PF15316.1 EGF99667.1 - 0.16 11.9 1.2 0.23 11.4 0.1 1.8 2 0 0 2 2 2 0 MyoD family inhibitor NuiA PF07924.6 EGF99669.1 - 0.024 14.5 0.1 0.078 12.8 0.0 1.8 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein DUF1158 PF06643.6 EGF99669.1 - 0.15 12.4 0.6 0.54 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1158) Sad1_UNC PF07738.8 EGF99670.1 - 4.3e-30 104.2 0.0 7.4e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RhoGEF PF00621.15 EGF99670.1 - 0.047 13.5 0.1 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 RhoGEF domain Epsilon_antitox PF08998.6 EGF99670.1 - 0.052 13.5 0.4 0.19 11.7 0.1 2.0 2 0 0 2 2 2 0 Bacterial epsilon antitoxin NPV_P10 PF05531.7 EGF99670.1 - 0.15 12.2 0.9 0.52 10.6 0.6 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1399 PF07173.7 EGF99671.1 - 0.024 14.9 0.5 2.7 8.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1399) PRANC PF09372.5 EGF99671.1 - 0.1 12.5 0.4 0.25 11.3 0.1 1.8 1 1 0 2 2 2 0 PRANC domain Ribosomal_L14 PF00238.14 EGF99673.1 - 6.9e-42 142.0 0.4 8e-42 141.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Peroxidase_2 PF01328.12 EGF99674.1 - 3.1e-13 49.0 0.1 5e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Lipase_GDSL PF00657.17 EGF99675.1 - 3.5e-05 23.7 0.0 4.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EGF99675.1 - 7.9e-05 22.8 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Sld5 PF05916.6 EGF99678.1 - 6.5e-05 23.1 0.2 0.00014 22.1 0.1 1.6 1 1 0 1 1 1 1 GINS complex protein JAB PF01398.16 EGF99679.1 - 4.2e-34 116.6 0.0 7.9e-34 115.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGF99679.1 - 1.5e-28 99.1 3.5 3.4e-28 98.0 2.5 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EGF99679.1 - 9.1e-08 31.6 0.0 1.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PcfJ PF14284.1 EGF99679.1 - 0.032 13.7 0.1 0.047 13.1 0.1 1.2 1 0 0 1 1 1 0 PcfJ-like protein UPF0172 PF03665.8 EGF99679.1 - 0.071 12.5 0.6 0.22 10.9 0.0 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) Exotox-A_target PF09102.5 EGF99679.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Exotoxin A, targeting Abhydrolase_5 PF12695.2 EGF99680.1 - 4.2e-12 46.0 0.1 1.1e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGF99680.1 - 1.6e-10 41.2 2.7 2.1e-10 40.8 1.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EGF99680.1 - 0.0021 17.5 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 EGF99680.1 - 0.0037 17.0 0.1 0.0093 15.7 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EGF99680.1 - 0.055 12.6 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Cohesin_HEAT PF12765.2 EGF99684.1 - 0.022 14.7 0.1 0.059 13.3 0.1 1.7 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Rho_N PF07498.7 EGF99689.1 - 0.014 15.1 0.7 0.17 11.6 0.2 2.2 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain FlxA PF14282.1 EGF99689.1 - 2.5 8.0 6.0 1.4 8.9 1.4 2.0 1 1 1 2 2 2 0 FlxA-like protein Tir_receptor_M PF03549.9 EGF99690.1 - 1.2 9.2 5.3 0.82 9.8 0.1 2.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) intimin-binding domain Muted PF14942.1 EGF99696.1 - 2.7 7.8 7.5 20 5.0 1.9 2.6 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein IMPDH PF00478.20 EGF99697.1 - 2.8e-05 23.1 1.6 0.00082 18.3 1.1 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Pkinase PF00069.20 EGF99698.1 - 3e-36 124.9 0.0 4.2e-21 75.2 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGF99698.1 - 2.8e-15 56.1 0.0 8.9e-13 47.9 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGF99698.1 - 0.0018 18.0 0.0 0.0069 16.1 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGF99698.1 - 0.0034 16.3 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EGF99698.1 - 0.025 13.6 0.3 0.099 11.6 0.2 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S2 PF00318.15 EGF99699.1 - 1.3e-45 155.1 0.0 1.6e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 Citrate_synt PF00285.16 EGF99700.1 - 9.6e-117 389.6 0.0 1.1e-116 389.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Lipase_GDSL PF00657.17 EGF99701.1 - 5.1e-09 36.2 2.6 9.3e-09 35.4 1.8 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EGF99701.1 - 4.7e-07 30.0 0.1 6.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DER1 PF04511.10 EGF99702.1 - 1.2e-49 168.5 5.8 1.3e-49 168.3 4.0 1.0 1 0 0 1 1 1 1 Der1-like family F-box-like PF12937.2 EGF99703.1 - 0.0011 18.6 0.2 0.0041 16.8 0.0 2.1 2 0 0 2 2 2 1 F-box-like PCI_Csn8 PF10075.4 EGF99704.1 - 3.6e-29 101.3 0.7 1.3e-28 99.6 0.0 2.0 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EGF99704.1 - 4.2e-28 98.3 0.0 6.9e-28 97.6 0.0 1.4 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family BING4CT PF08149.6 EGF99704.1 - 0.0054 16.2 0.1 2.1 7.8 0.1 2.5 2 0 0 2 2 2 2 BING4CT (NUC141) domain eIF2A PF08662.6 EGF99705.1 - 4.4e-82 274.5 1.1 1.7e-79 266.0 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EGF99705.1 - 0.00093 18.9 0.2 18 5.4 0.0 4.7 4 1 0 4 4 4 1 WD domain, G-beta repeat SprA-related PF12118.3 EGF99705.1 - 0.11 11.7 11.0 0.027 13.8 4.5 2.0 2 0 0 2 2 2 0 SprA-related family DUF4407 PF14362.1 EGF99705.1 - 0.35 9.7 2.6 0.49 9.2 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDV3 PF15359.1 EGF99705.1 - 1.1 9.3 9.6 0.099 12.7 1.3 2.9 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 NlpE PF04170.7 EGF99705.1 - 3.8 7.9 7.0 5.9 7.3 0.0 3.1 3 0 0 3 3 3 0 NlpE N-terminal domain RNase_T PF00929.19 EGF99706.1 - 2.8e-24 86.2 0.1 8.6e-24 84.6 0.1 1.6 1 1 0 1 1 1 1 Exonuclease SKN1 PF03935.10 EGF99707.1 - 5e-168 559.3 12.0 5.6e-168 559.2 8.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) RRM_1 PF00076.17 EGF99708.1 - 7.7e-07 28.6 0.0 1.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGF99708.1 - 0.00069 19.5 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGF99708.1 - 0.072 12.9 0.0 0.22 11.3 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 EGF99708.1 - 1.3 9.0 4.7 0.18 11.8 0.4 1.6 2 0 0 2 2 2 0 CASC3/Barentsz eIF4AIII binding Thioredoxin_6 PF13848.1 EGF99710.1 - 5.5e-08 32.8 0.0 5.5e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like domain Gal_mutarotas_2 PF13802.1 EGF99711.1 - 2.1e-06 27.4 0.6 2.5e-06 27.2 0.4 1.2 1 0 0 1 1 1 1 Galactose mutarotase-like MIF4G PF02854.14 EGF99712.1 - 1e-54 185.1 1.1 1.8e-54 184.3 0.8 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EGF99712.1 - 2.9e-19 68.7 0.1 1.2e-18 66.7 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 EGF99712.1 - 4.1e-08 32.9 0.3 4.7e-07 29.4 0.0 2.4 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 EGF99713.1 - 5.9e-52 176.1 1.1 7.7e-52 175.7 0.8 1.1 1 0 0 1 1 1 1 MIF4G domain DUF445 PF04286.7 EGF99713.1 - 0.93 8.9 8.1 16 4.9 5.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF445) MIF4G PF02854.14 EGF99714.1 - 5.7e-25 87.9 15.2 1e-24 87.1 10.5 1.4 1 1 0 1 1 1 1 MIF4G domain DNA_pol_alpha_N PF12254.3 EGF99714.1 - 3.4 7.5 11.4 0.56 10.0 3.0 2.6 3 0 0 3 3 3 0 DNA polymerase alpha subunit p180 N terminal Acyl_transf_3 PF01757.17 EGF99715.1 - 1.7e-09 36.9 34.7 2.8e-09 36.2 24.0 1.3 1 0 0 1 1 1 1 Acyltransferase family RasGEF_N PF00618.15 EGF99715.1 - 0.045 13.8 1.6 0.073 13.1 0.2 2.1 2 1 0 2 2 2 0 RasGEF N-terminal motif Mito_carr PF00153.22 EGF99716.1 - 6e-14 51.5 0.0 3.9e-06 26.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 EGF99720.1 - 6.5e-22 77.9 0.1 1.8e-18 66.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGF99720.1 - 6.2e-11 41.8 0.0 9.4e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGF99720.1 - 0.0027 17.4 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGF99720.1 - 0.018 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EGF99720.1 - 0.027 13.5 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGF99720.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-U1 PF06220.7 EGF99721.1 - 4.4e-19 67.7 1.9 6.6e-19 67.1 1.3 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EGF99721.1 - 0.6 10.3 5.2 2.3 8.4 3.6 1.9 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF1993 PF09351.5 EGF99722.1 - 0.029 14.2 0.1 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) CRAL_TRIO PF00650.15 EGF99728.1 - 7.8e-33 113.2 0.1 1.3e-32 112.5 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EGF99728.1 - 4.6e-10 39.5 0.1 9.4e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGF99728.1 - 2.6e-06 27.4 0.0 6.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain BATS PF06968.8 EGF99729.1 - 1.4e-26 92.1 0.0 3.2e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EGF99729.1 - 7.1e-16 58.8 0.0 1.3e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Glyco_transf_28 PF03033.15 EGF99730.1 - 4.6e-21 75.0 0.0 9.9e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 EGF99730.1 - 3.6e-05 23.9 0.1 0.00024 21.2 0.0 2.4 3 0 0 3 3 3 1 PH domain UDPGT PF00201.13 EGF99730.1 - 0.00013 20.6 0.1 0.00029 19.5 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase GRAM PF02893.15 EGF99730.1 - 0.0014 18.0 0.0 1.8 8.1 0.0 3.2 3 0 0 3 3 3 2 GRAM domain DUF3068 PF11271.3 EGF99731.1 - 0.022 13.8 0.2 0.031 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) SSP160 PF06933.6 EGF99731.1 - 0.29 9.0 1.7 0.41 8.5 1.2 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HSP70 PF00012.15 EGF99732.1 - 2.1e-239 795.5 7.1 2.5e-239 795.2 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGF99732.1 - 7.5e-15 54.3 0.5 7.9e-14 50.9 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EGF99732.1 - 0.00059 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 EGF99732.1 - 0.027 13.4 0.0 0.067 12.1 0.0 1.6 1 0 0 1 1 1 0 StbA protein eIF2A PF08662.6 EGF99733.1 - 3.3e-34 118.3 0.3 6.1e-31 107.6 0.1 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A SAC3_GANP PF03399.11 EGF99734.1 - 2.4e-09 37.0 0.0 2.7e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGF99735.1 - 4.8e-11 42.5 0.1 2.2e-10 40.4 0.1 1.8 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EGF99735.1 - 6.7e-06 25.8 0.0 9.8e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Syntaxin_2 PF14523.1 EGF99737.1 - 0.024 14.6 1.7 0.055 13.4 1.2 1.5 1 0 0 1 1 1 0 Syntaxin-like protein PTS-HPr PF00381.14 EGF99737.1 - 0.061 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 PTS HPr component phosphorylation site PLATZ PF04640.9 EGF99737.1 - 0.1 12.8 0.1 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 PLATZ transcription factor Proteasome PF00227.21 EGF99740.1 - 4.1e-47 159.9 0.2 4.7e-47 159.7 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit CdCA1 PF10563.4 EGF99740.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat 14-3-3 PF00244.15 EGF99741.1 - 1e-115 384.7 4.5 1.2e-115 384.5 3.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EGF99741.1 - 0.0011 18.8 0.3 0.73 9.8 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF837 PF05769.6 EGF99741.1 - 0.023 14.2 3.4 0.19 11.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF837) SPRY PF00622.23 EGF99743.1 - 8e-11 42.1 0.0 5.3e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 SPRY domain DUF1115 PF06544.7 EGF99744.1 - 5.4e-09 35.7 0.4 9.4e-09 35.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF781 PF05612.7 EGF99745.1 - 0.052 12.2 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 Mouse protein of unknown function (DUF781) AAA_5 PF07728.9 EGF99746.1 - 2.7e-51 172.9 0.0 2e-23 82.6 0.0 3.5 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 EGF99746.1 - 0.0044 17.1 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_16 PF13191.1 EGF99746.1 - 0.066 13.1 0.1 12 5.8 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain vWA-TerF-like PF10138.4 EGF99746.1 - 0.2 11.4 0.0 0.54 10.0 0.0 1.7 2 0 0 2 2 2 0 vWA found in TerF C terminus Pkinase PF00069.20 EGF99747.1 - 8.9e-43 146.3 0.0 1.3e-36 126.0 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGF99747.1 - 1e-22 80.4 0.0 5e-19 68.3 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGF99747.1 - 0.00026 20.7 0.0 0.00033 20.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGF99747.1 - 0.00079 18.4 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 EGF99747.1 - 0.028 13.2 0.3 0.056 12.2 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 EGF99747.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EGF99747.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRP7 PF12923.2 EGF99748.1 - 6.2e-16 58.6 21.3 5.3e-13 49.1 14.8 3.0 1 1 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) zf-CCHH PF10283.4 EGF99749.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger (CX5CX6HX5H) motif F-box-like PF12937.2 EGF99750.1 - 7.6e-06 25.5 0.2 1.8e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGF99750.1 - 0.0049 16.4 0.0 0.014 15.0 0.0 1.8 1 1 0 1 1 1 1 F-box domain POT1 PF02765.12 EGF99752.1 - 0.0071 16.2 0.0 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 HMG_box PF00505.14 EGF99753.1 - 0.1 12.8 0.2 1.2 9.4 0.0 2.7 2 1 0 2 2 2 0 HMG (high mobility group) box DUF1161 PF06649.7 EGF99753.1 - 0.11 12.4 0.1 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1161) DUF2357 PF09823.4 EGF99753.1 - 0.12 11.4 0.4 7.7 5.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2357) PI3Ka PF00613.15 EGF99754.1 - 0.052 12.7 0.1 0.069 12.3 0.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Disulph_isomer PF06491.6 EGF99756.1 - 0.036 13.9 0.2 0.049 13.4 0.1 1.2 1 0 0 1 1 1 0 Disulphide isomerase CelD_N PF02927.9 EGF99760.1 - 0.052 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal ig-like domain of cellulase zf-C2H2 PF00096.21 EGF99761.1 - 0.035 14.4 1.0 4.2 7.9 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGF99761.1 - 0.071 13.4 1.6 0.96 9.9 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger HemY_N PF07219.8 EGF99762.1 - 0.27 10.7 1.2 0.47 10.0 0.8 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Helitron_like_N PF14214.1 EGF99764.1 - 0.069 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus Abhydrolase_6 PF12697.2 EGF99765.1 - 2.1e-11 44.1 0.0 2.7e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGF99765.1 - 1.5e-06 27.9 0.0 3.8e-06 26.6 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold HOOK PF05622.7 EGF99767.1 - 0.0033 15.3 2.5 0.0041 14.9 1.7 1.1 1 0 0 1 1 1 1 HOOK protein Fungal_trans_2 PF11951.3 EGF99767.1 - 0.013 14.1 0.5 0.015 13.9 0.3 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain TSC22 PF01166.13 EGF99767.1 - 0.017 15.0 9.3 0.44 10.5 0.8 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family Kinetocho_Slk19 PF12709.2 EGF99767.1 - 0.064 13.3 5.4 0.77 9.8 0.1 2.9 2 1 1 3 3 3 0 Central kinetochore-associated DUF848 PF05852.6 EGF99767.1 - 0.075 12.8 2.6 0.28 11.0 0.7 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) bZIP_1 PF00170.16 EGF99767.1 - 0.085 12.8 1.9 2.4 8.1 0.1 2.7 2 1 1 3 3 3 0 bZIP transcription factor DUF16 PF01519.11 EGF99767.1 - 0.18 12.0 3.8 0.32 11.2 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 bZIP_2 PF07716.10 EGF99767.1 - 0.21 11.4 4.7 12 5.7 0.6 3.1 2 1 1 3 3 3 0 Basic region leucine zipper Tup_N PF08581.5 EGF99767.1 - 0.39 10.9 4.0 0.21 11.7 1.0 1.9 2 1 0 2 2 2 0 Tup N-terminal RB_B PF01857.15 EGF99767.1 - 0.49 9.9 5.1 8.5 5.8 0.3 2.5 2 1 0 2 2 2 0 Retinoblastoma-associated protein B domain DUF4041 PF13250.1 EGF99767.1 - 1 8.9 4.2 4.9 6.7 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) Nnf1 PF03980.9 EGF99767.1 - 1.1 9.2 8.5 1.1e+02 2.9 5.9 3.5 1 1 0 1 1 1 0 Nnf1 Herpes_BLRF2 PF05812.7 EGF99767.1 - 1.2 8.9 3.6 22 4.8 0.3 2.6 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein FlxA PF14282.1 EGF99767.1 - 4.9 7.1 9.8 2 8.4 3.4 2.2 1 1 2 3 3 3 0 FlxA-like protein SR-25 PF10500.4 EGF99768.1 - 0.0011 18.4 10.9 0.0011 18.4 7.5 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF572 PF04502.8 EGF99768.1 - 5 6.2 12.3 7 5.7 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Glycophorin_A PF01102.13 EGF99768.1 - 5.5 6.7 8.2 2.6 7.8 1.2 2.3 2 0 0 2 2 2 0 Glycophorin A DUF2890 PF11081.3 EGF99769.1 - 0.00032 20.7 0.8 0.00042 20.4 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) DUF4367 PF14285.1 EGF99769.1 - 0.74 9.1 4.7 1.5 8.1 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) Nop14 PF04147.7 EGF99769.1 - 1 7.2 13.1 1.2 6.9 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EGF99769.1 - 2.4 7.3 12.4 3.3 6.9 8.6 1.1 1 0 0 1 1 1 0 SDA1 THAP PF05485.7 EGF99770.1 - 0.19 11.9 1.1 5.7 7.1 0.0 2.3 2 0 0 2 2 2 0 THAP domain SNase PF00565.12 EGF99771.1 - 0.022 15.0 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Staphylococcal nuclease homologue Pectinesterase PF01095.14 EGF99774.1 - 0.2 10.1 0.7 0.28 9.7 0.5 1.2 1 0 0 1 1 1 0 Pectinesterase adh_short PF00106.20 EGF99775.1 - 6.6e-15 55.4 0.1 2.7e-14 53.4 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGF99775.1 - 7e-09 35.6 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGF99775.1 - 9.6e-08 32.0 0.0 2e-07 31.0 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF2824 PF11039.3 EGF99775.1 - 0.00018 21.2 0.0 0.00057 19.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2824) DUF4629 PF15442.1 EGF99777.1 - 0.018 15.1 7.5 0.024 14.7 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) TATR PF03430.8 EGF99777.1 - 0.3 9.6 4.1 0.34 9.4 2.9 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Pkinase PF00069.20 EGF99778.1 - 6e-63 212.4 0.1 7e-63 212.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF99778.1 - 3.5e-31 108.2 0.1 4.4e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGF99778.1 - 2.3e-07 30.1 0.0 4.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGF99778.1 - 0.0015 18.3 0.0 0.16 11.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGF99778.1 - 0.038 13.0 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP_bind_1 PF03029.12 EGF99779.1 - 4.3e-70 235.9 0.0 5.3e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EGF99779.1 - 4.6e-05 24.2 0.2 0.00017 22.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 EGF99779.1 - 0.0022 17.2 0.0 0.0054 15.9 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 EGF99779.1 - 0.0034 17.3 3.0 0.016 15.1 1.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EGF99779.1 - 0.0075 16.1 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ImcF-related_N PF14331.1 EGF99779.1 - 0.0099 14.8 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain AAA_19 PF13245.1 EGF99779.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain CbiA PF01656.18 EGF99779.1 - 0.023 14.1 0.0 0.049 13.0 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.1 EGF99779.1 - 0.026 14.1 0.0 0.053 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EGF99779.1 - 0.043 14.0 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EGF99779.1 - 0.049 13.0 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EGF99779.1 - 0.1 12.7 0.0 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGF99779.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGF99779.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EGF99779.1 - 0.12 12.6 0.9 0.35 11.1 0.1 2.3 1 1 0 2 2 2 0 AAA domain UDPGP PF01704.13 EGF99780.1 - 5.2e-54 183.3 0.0 6.7e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EGF99780.1 - 0.022 14.8 0.0 0.052 13.6 0.0 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain MIP PF00230.15 EGF99782.1 - 2.5e-42 144.8 18.8 3.3e-42 144.5 13.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_47 PF01532.15 EGF99783.1 - 1.9e-78 264.1 0.3 8.6e-75 252.1 0.2 3.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Neugrin PF06413.6 EGF99784.1 - 0.03 14.1 1.7 0.03 14.1 1.2 1.0 1 0 0 1 1 1 0 Neugrin Cytadhesin_P30 PF07271.6 EGF99784.1 - 0.078 12.2 1.0 0.12 11.6 0.7 1.3 1 1 0 1 1 1 0 Cytadhesin P30/P32 DUF1155 PF06633.6 EGF99785.1 - 0.027 13.7 0.0 0.059 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) Med9 PF07544.8 EGF99789.1 - 0.00047 19.8 2.2 0.0067 16.1 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.7 EGF99789.1 - 0.0038 17.4 6.1 0.46 10.7 0.3 2.4 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein SRA1 PF07304.6 EGF99789.1 - 0.0042 16.8 0.1 0.0056 16.4 0.1 1.3 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) DHC_N2 PF08393.8 EGF99789.1 - 0.0092 14.5 1.2 0.012 14.0 0.8 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Reo_sigmaC PF04582.7 EGF99789.1 - 0.0094 15.1 1.0 0.013 14.6 0.7 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein CCDC-167 PF15188.1 EGF99789.1 - 0.012 15.5 1.6 0.026 14.4 1.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Baculo_PEP_C PF04513.7 EGF99789.1 - 0.015 15.1 5.2 0.031 14.1 3.0 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CALCOCO1 PF07888.6 EGF99789.1 - 0.019 13.3 3.3 0.022 13.1 2.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.6 EGF99789.1 - 0.021 13.4 3.5 0.026 13.1 2.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.4 EGF99789.1 - 0.026 13.0 5.4 0.16 10.4 0.4 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 Transcrip_act PF04949.8 EGF99789.1 - 0.033 13.8 1.7 0.76 9.3 0.1 2.2 1 1 1 2 2 2 0 Transcriptional activator Filament PF00038.16 EGF99789.1 - 0.037 13.5 3.8 0.046 13.1 2.2 1.4 1 1 0 1 1 1 0 Intermediate filament protein AAA_13 PF13166.1 EGF99789.1 - 0.037 12.4 2.0 0.053 11.9 1.4 1.3 1 0 0 1 1 1 0 AAA domain Snapin_Pallidin PF14712.1 EGF99789.1 - 0.063 13.5 2.7 0.13 12.6 1.9 1.5 1 0 0 1 1 1 0 Snapin/Pallidin GAS PF13851.1 EGF99789.1 - 0.1 11.7 3.8 0.14 11.3 2.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4446 PF14584.1 EGF99789.1 - 0.14 11.9 2.1 7.5 6.3 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) TBPIP PF07106.8 EGF99789.1 - 0.17 11.3 4.2 0.55 9.7 2.4 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4315 PF14193.1 EGF99789.1 - 0.18 11.7 1.5 2.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) DivIC PF04977.10 EGF99789.1 - 0.22 11.0 3.3 6.2 6.3 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.6 EGF99789.1 - 0.23 11.3 2.8 3.5 7.5 0.2 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.12 EGF99789.1 - 0.3 10.7 4.7 1.4 8.5 0.2 2.4 1 1 1 2 2 2 0 Prefoldin subunit COG2 PF06148.6 EGF99789.1 - 0.33 10.8 5.4 1.9 8.3 0.3 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 EGF99789.1 - 0.35 10.6 5.2 1.1 9.0 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.7 EGF99789.1 - 0.37 11.1 5.2 3.7 7.9 0.4 3.0 1 1 2 3 3 3 0 SlyX YscO PF07321.7 EGF99789.1 - 0.66 9.7 5.4 9.3 6.0 1.6 2.1 1 1 1 2 2 2 0 Type III secretion protein YscO DUF3373 PF11853.3 EGF99789.1 - 0.7 8.3 5.4 2.3 6.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) FlxA PF14282.1 EGF99789.1 - 0.79 9.6 4.5 4.4 7.2 3.1 1.9 1 1 0 1 1 1 0 FlxA-like protein DUF4200 PF13863.1 EGF99789.1 - 0.82 9.6 4.8 5.2 7.0 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HR1 PF02185.11 EGF99789.1 - 0.86 9.3 3.9 6.5 6.5 0.2 2.8 1 1 1 2 2 2 0 Hr1 repeat Spc24 PF08286.6 EGF99789.1 - 1 9.0 4.8 3.2 7.4 0.3 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF948 PF06103.6 EGF99789.1 - 1.2 9.0 7.0 7.3 6.5 0.5 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4404 PF14357.1 EGF99789.1 - 1.4 9.3 5.8 18 5.8 0.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF4140 PF13600.1 EGF99789.1 - 1.6 9.2 4.7 18 5.8 0.2 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.6 EGF99789.1 - 2.9 7.6 7.2 4.2 7.1 0.6 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Asparaginase PF00710.15 EGF99792.1 - 1e-102 343.2 0.0 1.3e-102 342.9 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EGF99792.1 - 2e-12 47.2 1.2 5.3e-12 45.9 0.6 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGF99792.1 - 3.9e-11 43.1 3.5 2.1e-10 40.8 0.8 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EGF99792.1 - 7.7e-11 41.2 9.7 3.8e-08 32.7 0.2 4.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 EGF99792.1 - 1.4e-09 37.8 0.3 5.3e-09 36.0 0.2 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGF99792.1 - 9.8e-07 28.4 4.3 0.00032 20.6 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat ubiquitin PF00240.18 EGF99794.1 - 9.6e-18 63.3 0.1 1.6e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EGF99794.1 - 1.2e-10 40.8 0.1 1.2e-10 40.8 0.0 2.6 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.3 EGF99794.1 - 4.1e-06 26.3 0.0 7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGF99794.1 - 9.1e-06 25.7 0.1 1.5e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain CUE PF02845.11 EGF99794.1 - 0.001 18.4 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain Rad60-SLD_2 PF13881.1 EGF99794.1 - 0.0077 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Cohesin_HEAT PF12765.2 EGF99794.1 - 0.069 13.1 3.4 2.4 8.1 0.0 3.9 3 1 1 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Piwi PF02171.12 EGF99795.1 - 3.7e-21 75.3 0.0 4e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Piwi domain DUF3510 PF12022.3 EGF99797.1 - 1.2e-12 48.0 1.1 3.8e-12 46.3 0.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) DUF4570 PF15134.1 EGF99797.1 - 0.053 13.3 1.4 0.13 12.0 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Syntaxin_2 PF14523.1 EGF99798.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 1 0 1 1 1 0 Syntaxin-like protein Symplekin_C PF12295.3 EGF99798.1 - 0.13 12.1 0.1 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal CLTH PF10607.4 EGF99801.1 - 2.1e-29 102.0 0.0 4.6e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EGF99801.1 - 0.0043 16.7 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 LisH DASH_Dad3 PF08656.5 EGF99801.1 - 0.1 12.2 0.3 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad3 Ribosomal_L31 PF01197.13 EGF99802.1 - 0.00066 19.6 0.3 0.0029 17.5 0.0 2.1 3 0 0 3 3 3 1 Ribosomal protein L31 zf-DHHC PF01529.15 EGF99803.1 - 2.8e-42 144.0 4.2 4.8e-42 143.3 2.9 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.2 EGF99803.1 - 0.58 10.0 7.6 0.9 9.4 5.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon WIF PF02019.13 EGF99805.1 - 0.027 13.9 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 WIF domain Rsm22 PF09243.5 EGF99807.1 - 1.1e-53 182.0 0.1 1.6e-45 155.2 0.0 2.4 1 1 1 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_31 PF13847.1 EGF99807.1 - 0.00078 19.0 0.5 0.021 14.4 0.2 3.1 2 1 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 EGF99807.1 - 0.0035 16.7 0.0 0.011 15.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EGF99807.1 - 0.021 15.3 0.1 0.23 11.9 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EGF99807.1 - 0.12 13.0 0.0 0.73 10.4 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain zf-DHHC PF01529.15 EGF99808.1 - 6.9e-29 100.4 15.8 6.9e-29 100.4 11.0 2.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase Mito_fiss_reg PF05308.6 EGF99808.1 - 1.1 8.5 6.7 1.6 8.0 4.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator FYVE PF01363.16 EGF99808.1 - 7.8 6.4 10.2 34 4.4 6.9 2.1 1 1 1 2 2 2 0 FYVE zinc finger FIVAR PF07554.8 EGF99810.1 - 0.026 14.7 1.7 0.46 10.7 0.3 3.2 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain PAH PF02671.16 EGF99814.1 - 1.6e-37 126.8 0.9 8.6e-16 57.2 0.5 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EGF99814.1 - 2.1e-28 98.0 0.0 5.6e-28 96.6 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor EF-hand_1 PF00036.27 EGF99815.1 - 7.8e-27 90.5 16.7 1.7e-09 36.2 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGF99815.1 - 1.1e-24 86.3 10.8 4.3e-13 49.1 2.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGF99815.1 - 2e-22 76.9 13.0 9.3e-09 34.4 0.1 4.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 EGF99815.1 - 4.5e-17 61.4 15.1 2.6e-10 39.7 1.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EGF99815.1 - 1.5e-14 52.5 13.8 4.4e-06 25.7 0.1 4.0 3 1 1 4 4 4 3 EF hand EF-hand_9 PF14658.1 EGF99815.1 - 2.9e-09 36.6 0.2 0.00031 20.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EGF99815.1 - 6.9e-07 28.9 5.3 0.00056 19.6 0.1 2.6 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand DUF3164 PF11363.3 EGF99815.1 - 0.0034 16.7 0.9 2.4 7.5 0.1 2.9 1 1 0 2 2 2 2 Protein of unknown function (DUF3164) SPARC_Ca_bdg PF10591.4 EGF99815.1 - 0.0041 17.1 4.3 0.4 10.7 0.5 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 EGF99815.1 - 0.044 13.3 0.1 0.29 10.6 0.0 2.1 2 1 0 2 2 2 0 Caleosin related protein Toprim_2 PF13155.1 EGF99815.1 - 0.084 13.1 3.1 5.6 7.3 0.3 2.7 1 1 1 2 2 2 0 Toprim-like DNA_pol_B_thumb PF14791.1 EGF99815.1 - 0.2 11.3 0.8 8.2 6.1 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase beta thumb MgtE_N PF03448.12 EGF99815.1 - 0.44 10.9 5.6 0.31 11.3 0.8 2.4 3 0 0 3 3 2 0 MgtE intracellular N domain EF-hand_like PF09279.6 EGF99815.1 - 3.7 7.6 6.2 1.4 8.9 0.9 2.4 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like SEO_C PF14577.1 EGF99816.1 - 0.063 12.6 0.1 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Sieve element occlusion C-terminus LRV_FeS PF05484.6 EGF99816.1 - 0.2 11.2 8.0 0.054 13.0 2.7 1.9 1 1 1 2 2 2 0 LRV protein FeS4 cluster Zn_ribbon_recom PF13408.1 EGF99816.1 - 0.81 9.9 15.4 7.4 6.9 10.7 2.2 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Neur_chan_memb PF02932.11 EGF99817.1 - 0.11 12.4 1.2 0.58 10.0 0.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PBP_sp32 PF07222.7 EGF99817.1 - 2.1 7.4 9.1 3.7 6.6 6.3 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pex16 PF08610.5 EGF99817.1 - 6.4 5.6 5.8 9.5 5.1 4.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF512 PF04459.7 EGF99819.1 - 0.025 13.6 0.2 0.069 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Porin_O_P PF07396.6 EGF99820.1 - 0.023 13.5 0.0 0.03 13.2 0.0 1.1 1 0 0 1 1 1 0 Phosphate-selective porin O and P Asp PF00026.18 EGF99822.1 - 2.1e-60 204.6 3.7 2.5e-60 204.3 2.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGF99822.1 - 1.6e-08 34.6 0.1 6.4e-08 32.7 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Velvet PF11754.3 EGF99823.1 - 5.3e-29 101.2 0.0 9e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Velvet factor DUF1399 PF07173.7 EGF99824.1 - 8.9e-11 42.2 0.0 2.8e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1399) Aminotran_1_2 PF00155.16 EGF99825.1 - 6.9e-10 38.4 0.0 8.8e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Enolase_C PF00113.17 EGF99826.1 - 1.1e-145 484.1 0.1 1.5e-145 483.6 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EGF99826.1 - 4.2e-58 194.9 0.8 7.4e-58 194.1 0.5 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EGF99826.1 - 0.00024 21.0 0.3 0.00078 19.4 0.0 2.0 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EGF99826.1 - 0.0026 16.7 1.8 0.0037 16.2 0.2 1.9 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EGF99826.1 - 0.015 15.7 0.0 0.042 14.3 0.0 1.8 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Glyco_hydro_47 PF01532.15 EGF99828.1 - 3.7e-120 401.6 0.0 4.4e-120 401.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Na_Ca_ex PF01699.19 EGF99829.1 - 6.3e-20 71.2 14.9 1.4e-19 70.1 10.3 1.6 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF2157 PF09925.4 EGF99829.1 - 0.46 10.0 5.2 2.5 7.6 0.3 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) UPF0203 PF05254.7 EGF99830.1 - 5.3e-20 71.0 1.1 6.3e-20 70.8 0.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 EGF99830.1 - 0.0023 17.8 0.3 0.0045 16.9 0.2 1.5 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.8 EGF99830.1 - 0.27 11.2 1.7 0.49 10.3 0.2 2.0 2 0 0 2 2 2 0 CHCH domain COX6B PF02297.12 EGF99830.1 - 0.59 10.1 4.6 6.8 6.7 0.3 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DUF1399 PF07173.7 EGF99833.1 - 6.7e-26 91.1 1.5 7.8e-17 61.8 0.0 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF1399) Metallophos_2 PF12850.2 EGF99834.1 - 3.9e-15 56.0 0.0 6.3e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Med13_C PF06333.7 EGF99834.1 - 1.8 7.0 4.9 2.2 6.7 3.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal DUF605 PF04652.11 EGF99834.1 - 8.6 5.6 15.4 11 5.3 10.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF3275 PF11679.3 EGF99834.1 - 9 5.8 7.4 14 5.2 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Glyco_hydro_12 PF01670.11 EGF99835.1 - 3.7e-17 62.5 0.3 6.2e-17 61.8 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_hydro_12 PF01670.11 EGF99836.1 - 1.9e-18 66.7 0.1 2.9e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 WD40 PF00400.27 EGF99837.1 - 0.0028 17.4 4.2 0.42 10.5 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat FTP PF07504.8 EGF99838.1 - 2.1 7.8 0.0 2.1 7.8 0.0 3.8 5 0 0 5 5 5 0 Fungalysin/Thermolysin Propeptide Motif DnaJ PF00226.26 EGF99840.1 - 1.1e-23 82.7 0.2 3.4e-23 81.1 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 EGF99840.1 - 2.5e-09 37.3 8.9 3.9e-05 23.8 0.5 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1977) Tmpp129 PF10272.4 EGF99840.1 - 0.017 13.8 0.0 0.023 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor Pex14_N PF04695.8 EGF99840.1 - 1.1 9.2 7.8 0.21 11.6 1.6 2.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAP2 PF01569.16 EGF99841.1 - 1.9e-18 66.3 2.9 1.9e-18 66.3 2.0 2.9 3 1 0 3 3 3 1 PAP2 superfamily Pex14_N PF04695.8 EGF99841.1 - 0.027 14.5 8.8 0.11 12.5 0.4 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_S26e PF01283.14 EGF99842.1 - 2.1e-52 176.2 7.4 2.3e-52 176.0 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 EGF99842.1 - 0.042 14.2 2.1 0.24 11.7 0.3 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain Ferritin_2 PF13668.1 EGF99843.1 - 1.5e-20 73.5 0.0 2.4e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Ras PF00071.17 EGF99845.1 - 1e-14 54.2 0.1 1.4e-14 53.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Glyco_hydro_16 PF00722.16 EGF99846.1 - 1.4e-10 40.7 0.0 2.4e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Herpes_gE PF02480.11 EGF99847.1 - 0.014 13.6 0.0 0.014 13.6 0.0 2.2 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Mem_trans PF03547.13 EGF99848.1 - 0.24 9.6 0.0 0.27 9.4 0.0 1.2 1 0 0 1 1 1 0 Membrane transport protein Ribosomal_L2_C PF03947.13 EGF99851.1 - 1.1e-41 141.7 2.4 1.8e-41 140.9 1.7 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGF99851.1 - 9.6e-13 47.9 0.1 2e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Actin PF00022.14 EGF99854.1 - 1.2e-160 534.2 0.0 1.4e-160 534.0 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGF99854.1 - 0.061 13.7 0.0 0.18 12.2 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2114 PF09887.4 EGF99854.1 - 0.066 11.5 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Methyltransf_29 PF03141.11 EGF99854.1 - 0.087 11.1 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Fungal_trans PF04082.13 EGF99855.1 - 1.6e-31 109.1 0.9 1.6e-31 109.1 0.6 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGF99855.1 - 1.9e-07 30.8 11.3 4.1e-07 29.7 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 EGF99855.1 - 4.1 6.1 33.2 8.3 5.1 23.0 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PNP_UDP_1 PF01048.15 EGF99858.1 - 1.6e-36 125.4 0.0 1.8e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily adh_short PF00106.20 EGF99859.1 - 1.5e-25 90.0 0.1 1.9e-25 89.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGF99859.1 - 1.3e-21 77.4 0.0 1.6e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGF99859.1 - 1.2e-06 28.3 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EGF99859.1 - 0.018 14.7 0.2 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MULE PF10551.4 EGF99861.1 - 7e-11 42.1 0.0 1.9e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 EGF99861.1 - 1e-07 31.2 15.1 0.0019 17.6 0.3 3.6 3 0 0 3 3 3 3 SWIM zinc finger XRN_N PF03159.13 EGF99864.1 - 7.9e-102 339.6 0.0 1.1e-101 339.2 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 EGF99864.1 - 0.00012 21.8 5.2 0.00019 21.2 3.6 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-C2HC PF01530.13 EGF99865.1 - 3.3 7.5 8.2 2.4 7.9 0.6 3.3 3 0 0 3 3 3 0 Zinc finger, C2HC type Dak2 PF02734.12 EGF99866.1 - 0.1 12.2 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 DAK2 domain Ribosomal_L35p PF01632.14 EGF99868.1 - 0.92 9.4 6.0 6 6.8 1.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L35 Inhibitor_I9 PF05922.11 EGF99870.1 - 0.0002 21.8 0.0 0.0002 21.8 0.0 2.7 3 1 0 3 3 3 1 Peptidase inhibitor I9 DUF3129 PF11327.3 EGF99871.1 - 2.8e-44 151.1 3.9 2.8e-44 151.1 2.7 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) DUF4557 PF15101.1 EGF99871.1 - 3.3 7.4 6.8 6.3 6.5 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Col_cuticle_N PF01484.12 EGF99872.1 - 0.085 12.5 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain CTP_transf_1 PF01148.15 EGF99874.1 - 8.2e-07 28.9 12.1 8.2e-07 28.9 8.4 4.0 3 1 0 3 3 3 1 Cytidylyltransferase family DUF1049 PF06305.6 EGF99874.1 - 0.27 10.7 2.6 1.2 8.7 0.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1049) Innate_immun PF12782.2 EGF99874.1 - 0.89 8.7 4.6 1.6 7.8 3.2 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family PXA PF02194.10 EGF99878.1 - 2.2e-08 33.8 2.4 7.1e-05 22.4 0.0 2.9 2 1 1 3 3 3 2 PXA domain Cation_efflux PF01545.16 EGF99878.1 - 0.04 12.9 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Cation efflux family DUF676 PF05057.9 EGF99880.1 - 4e-11 42.6 1.2 6.4e-11 41.9 0.0 1.9 3 0 0 3 3 3 1 Putative serine esterase (DUF676) DUF3685 PF12452.3 EGF99882.1 - 0.099 11.7 1.4 0.14 11.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) Wbp11 PF09429.5 EGF99883.1 - 7.1e-16 57.9 14.5 7.1e-16 57.9 10.1 1.8 2 0 0 2 2 2 1 WW domain binding protein 11 NpwBP PF12622.2 EGF99883.1 - 2.4e-06 27.9 21.0 2.4e-06 27.9 14.6 5.0 3 1 0 3 3 3 1 mRNA biogenesis factor TFIIA PF03153.8 EGF99883.1 - 0.094 12.5 10.6 0.031 14.1 4.6 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit 4HB_MCP_1 PF12729.2 EGF99883.1 - 0.21 10.9 3.3 0.32 10.3 2.3 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction S10_plectin PF03501.10 EGF99884.1 - 2.5e-42 142.6 0.2 3e-42 142.4 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF2250 PF10007.4 EGF99884.1 - 0.19 11.6 0.4 6.9 6.6 0.3 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) RNase_PH PF01138.16 EGF99885.1 - 1.2e-11 45.0 1.0 3.5e-10 40.2 0.7 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Coa1 PF08695.5 EGF99886.1 - 2.7e-24 84.9 0.0 4.1e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Acyl-CoA_dh_1 PF00441.19 EGF99887.1 - 1.4e-34 119.4 0.4 2e-34 118.8 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGF99887.1 - 2.4e-16 58.9 0.4 5.7e-16 57.7 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EGF99887.1 - 5.5e-15 54.9 0.0 1.2e-14 53.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EGF99887.1 - 1.9e-12 47.7 0.2 6.2e-12 46.0 0.0 2.0 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGF99887.1 - 2.6e-06 27.7 0.1 5.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain WD40 PF00400.27 EGF99888.1 - 2e-08 33.8 13.5 0.00078 19.2 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat DRMBL PF07522.9 EGF99889.1 - 4.9e-31 107.0 0.0 8.7e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EGF99889.1 - 2.1e-13 50.2 0.1 3.5e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGF99889.1 - 0.039 13.5 1.1 0.083 12.5 0.8 1.4 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EGF99889.1 - 0.058 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain URO-D PF01208.12 EGF99890.1 - 4e-108 361.3 0.0 4.5e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Ribonucleas_3_3 PF14622.1 EGF99893.1 - 0.03 14.3 0.0 18 5.3 0.0 3.6 4 0 0 4 4 4 0 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EGF99893.1 - 0.039 14.3 0.1 25 5.3 0.0 3.7 3 1 0 3 3 3 0 Ribonuclease III domain Adeno_E4_ORF3 PF06931.6 EGF99894.1 - 0.072 13.1 0.1 0.092 12.8 0.0 1.2 1 0 0 1 1 1 0 Mastadenovirus E4 ORF3 protein RasGEF PF00617.14 EGF99895.1 - 5.4e-61 205.6 0.2 8.1e-61 205.0 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGF99895.1 - 4e-24 84.7 0.5 1.1e-23 83.2 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif zf-U1 PF06220.7 EGF99897.1 - 5.7e-10 38.5 2.4 9.4e-10 37.8 1.7 1.4 1 0 0 1 1 1 1 U1 zinc finger DUF2476 PF10630.4 EGF99897.1 - 0.081 12.7 1.3 0.12 12.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2476) zf-C2H2_jaz PF12171.3 EGF99897.1 - 1.4 9.1 7.8 12 6.2 5.4 2.3 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ORC6 PF05460.8 EGF99898.1 - 0.2 10.7 6.5 0.22 10.6 4.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Astro_capsid PF03115.9 EGF99898.1 - 3.2 5.9 6.0 3.4 5.8 4.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Presenilin PF01080.12 EGF99898.1 - 3.5 6.3 4.4 5.1 5.8 3.1 1.3 1 1 0 1 1 1 0 Presenilin DUF3129 PF11327.3 EGF99900.1 - 6.4e-41 140.1 2.7 6.4e-41 140.1 1.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3129) Mito_carr PF00153.22 EGF99901.1 - 5.2e-59 195.9 1.1 1.8e-19 69.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_47 PF01532.15 EGF99902.1 - 3.1e-120 401.9 0.4 3.6e-120 401.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.9 EGF99902.1 - 0.072 12.4 0.1 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 CBFD_NFYB_HMF PF00808.18 EGF99903.1 - 6.4e-19 67.7 1.9 7.3e-19 67.5 1.3 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGF99903.1 - 2.8e-10 40.1 0.2 3e-10 40.0 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EGF99903.1 - 0.0012 18.6 0.1 0.0014 18.4 0.1 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAFII28 PF04719.9 EGF99903.1 - 0.0074 16.0 0.2 0.0081 15.9 0.1 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region TFIID-18kDa PF02269.11 EGF99903.1 - 0.0095 15.7 0.4 0.019 14.7 0.3 1.5 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TAF PF02969.12 EGF99903.1 - 0.011 15.6 0.3 0.017 15.0 0.2 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF3129 PF11327.3 EGF99905.1 - 2.5e-39 135.0 3.2 2.5e-39 135.0 2.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) HhH-GPD PF00730.20 EGF99906.1 - 4.3e-05 23.7 0.0 5.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGF99906.1 - 0.016 14.8 0.1 0.038 13.6 0.0 1.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 EGF99906.1 - 0.035 14.2 4.8 0.058 13.6 3.4 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III PPR_2 PF13041.1 EGF99907.1 - 5.7e-31 106.2 5.8 1.7e-11 43.8 0.1 9.8 8 2 4 12 12 12 7 PPR repeat family PPR PF01535.15 EGF99907.1 - 1.1e-26 90.9 8.5 1.3e-06 27.9 0.0 10.8 11 0 0 11 11 11 4 PPR repeat PPR_3 PF13812.1 EGF99907.1 - 1.3e-25 87.5 1.5 0.00029 20.8 0.0 9.9 9 1 1 10 10 9 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 EGF99907.1 - 2.5e-19 68.4 1.1 3.4e-06 26.4 0.0 6.8 6 0 0 6 6 6 4 PPR repeat TPR_14 PF13428.1 EGF99907.1 - 2.1e-08 34.0 0.7 0.36 11.6 0.0 7.5 9 0 0 9 9 7 1 Tetratricopeptide repeat RPM2 PF08579.6 EGF99907.1 - 2.1e-05 24.6 0.7 0.081 13.0 0.0 4.0 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.1 EGF99907.1 - 0.00021 21.5 0.2 16 5.9 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4423 PF14394.1 EGF99907.1 - 0.0012 18.4 0.1 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) TPR_6 PF13174.1 EGF99907.1 - 0.0044 17.3 0.5 0.68 10.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGF99907.1 - 0.042 14.5 0.0 31 5.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGF99907.1 - 0.045 14.1 0.0 2.2 8.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGF99907.1 - 0.073 13.0 0.1 97 3.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SH3_1 PF00018.23 EGF99908.1 - 4.2e-07 29.2 0.0 8.3e-07 28.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGF99908.1 - 0.0033 16.9 0.1 0.038 13.5 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain RNase_PH PF01138.16 EGF99909.1 - 3.8e-23 82.2 0.4 5.3e-23 81.7 0.3 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 CATSPERG PF15064.1 EGF99912.1 - 0.1 10.3 0.2 0.11 10.2 0.1 1.0 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma tRNA-synt_1b PF00579.20 EGF99913.1 - 9.8e-69 231.6 0.0 1.4e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF2638 PF10937.3 EGF99914.1 - 1.1e-09 39.2 1.6 1.6e-09 38.7 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) ACBP PF00887.14 EGF99915.1 - 3.8e-23 80.9 0.0 5.2e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein RRM_1 PF00076.17 EGF99917.1 - 4.2e-44 148.0 0.1 2.6e-22 78.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGF99917.1 - 1e-31 108.7 0.0 6.2e-15 54.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGF99917.1 - 1.6e-20 72.7 0.0 2.5e-12 46.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGF99917.1 - 0.021 14.5 0.0 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MAT1 PF06391.8 EGF99918.1 - 1.8e-35 122.3 20.1 2.1e-35 122.1 13.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EGF99918.1 - 2.3e-06 27.1 7.5 4.4e-06 26.2 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGF99918.1 - 7.7e-05 22.6 8.7 0.00014 21.8 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGF99918.1 - 8e-05 22.2 5.3 0.00015 21.4 3.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGF99918.1 - 0.0003 20.3 5.0 0.0007 19.2 3.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGF99918.1 - 0.00074 19.2 6.9 0.0013 18.5 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain IQ-like PF15157.1 EGF99918.1 - 0.0093 16.1 2.0 0.016 15.4 1.4 1.3 1 0 0 1 1 1 1 IQ-like zf-RING_4 PF14570.1 EGF99918.1 - 0.02 14.4 6.9 0.043 13.4 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Scaffolding_pro PF11418.3 EGF99918.1 - 0.035 14.4 3.1 0.068 13.4 2.1 1.6 1 1 0 1 1 1 0 Phi29 scaffolding protein FYDLN_acid PF09538.5 EGF99918.1 - 0.66 10.5 4.0 10 6.7 2.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING_UBOX PF13445.1 EGF99918.1 - 0.86 9.3 7.5 17 5.2 3.6 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGF99918.1 - 2.8 7.8 9.5 10 6.0 6.6 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Med10 PF09748.4 EGF99920.1 - 2.1e-16 59.9 0.0 3.1e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex UPF0047 PF01894.12 EGF99921.1 - 4.8e-11 42.4 0.9 9.7e-11 41.5 0.6 1.6 1 1 0 1 1 1 1 Uncharacterised protein family UPF0047 DUF1524 PF07510.6 EGF99921.1 - 0.096 12.5 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) HNH PF01844.18 EGF99921.1 - 1.4 8.8 5.3 6.4 6.7 1.2 2.2 2 0 0 2 2 2 0 HNH endonuclease Med26 PF08711.6 EGF99923.1 - 0.00089 18.7 0.4 0.002 17.5 0.3 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Phyto_Pns9_10 PF05878.6 EGF99923.1 - 0.086 11.8 0.7 0.15 11.0 0.5 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF3788 PF12663.2 EGF99924.1 - 0.056 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) DUF4407 PF14362.1 EGF99925.1 - 0.0038 16.2 1.0 0.0042 16.0 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CAF-1_p150 PF11600.3 EGF99925.1 - 0.0088 15.4 18.3 0.014 14.7 12.7 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal ADIP PF11559.3 EGF99925.1 - 0.014 15.3 1.4 0.023 14.6 1.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EGF99925.1 - 0.027 14.0 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 IncA protein CASP_C PF08172.7 EGF99925.1 - 0.077 12.0 2.0 0.1 11.5 1.4 1.4 1 0 0 1 1 1 0 CASP C terminal Vfa1 PF08432.5 EGF99925.1 - 0.079 12.9 17.7 0.13 12.2 12.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC27 PF09507.5 EGF99925.1 - 0.08 12.1 24.2 0.1 11.7 16.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mnd1 PF03962.10 EGF99925.1 - 0.1 12.2 3.1 0.14 11.8 2.2 1.1 1 0 0 1 1 1 0 Mnd1 family PBP_sp32 PF07222.7 EGF99925.1 - 0.15 11.1 3.7 0.27 10.3 2.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Effector_1 PF04518.7 EGF99925.1 - 0.19 10.6 3.0 0.24 10.3 2.1 1.1 1 0 0 1 1 1 0 Effector from type III secretion system Hex_IIIa PF02455.11 EGF99925.1 - 0.46 9.1 8.6 0.57 8.8 6.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF4337 PF14235.1 EGF99925.1 - 0.47 10.2 4.1 0.79 9.5 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DivIC PF04977.10 EGF99925.1 - 0.52 9.8 3.2 0.91 9.0 2.2 1.3 1 0 0 1 1 1 0 Septum formation initiator Spc24 PF08286.6 EGF99925.1 - 0.55 9.9 3.8 1 9.0 2.6 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Atg14 PF10186.4 EGF99925.1 - 0.79 8.6 5.3 1.2 8.0 3.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 EGF99925.1 - 1.2 9.1 7.3 1.6 8.7 4.8 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2796 PF10986.3 EGF99925.1 - 1.9 8.4 10.2 2.7 7.9 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Mitofilin PF09731.4 EGF99925.1 - 3.2 6.2 15.5 3.7 6.0 10.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1957 PF09210.6 EGF99930.1 - 0.13 12.3 0.3 11 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1957) Baculo_PEP_C PF04513.7 EGF99931.1 - 0.00085 19.1 1.7 0.0011 18.8 0.3 1.8 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.6 EGF99931.1 - 0.0013 17.9 5.8 0.0041 16.2 2.6 2.3 2 1 1 3 3 3 1 SF-assemblin/beta giardin Apolipoprotein PF01442.13 EGF99931.1 - 0.0025 17.3 0.2 0.0053 16.2 0.0 1.5 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF4618 PF15397.1 EGF99931.1 - 0.044 13.1 1.9 0.077 12.3 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) HIT PF01230.18 EGF99931.1 - 0.083 13.4 2.0 6.2 7.4 0.2 2.3 2 0 0 2 2 2 0 HIT domain PRP1_N PF06424.7 EGF99931.1 - 0.17 12.2 3.0 0.31 11.3 2.1 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF883 PF05957.8 EGF99931.1 - 0.42 11.0 3.1 2.6 8.4 0.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Fzo_mitofusin PF04799.8 EGF99931.1 - 0.54 9.6 2.8 0.48 9.7 1.0 1.6 2 0 0 2 2 2 0 fzo-like conserved region NPV_P10 PF05531.7 EGF99931.1 - 2.3 8.5 5.2 63 3.9 3.6 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein KAR9 PF08580.5 EGF99931.1 - 3.2 5.8 7.5 0.19 10.0 0.4 1.9 1 1 1 2 2 2 0 Yeast cortical protein KAR9 RRM_1 PF00076.17 EGF99935.1 - 3.1e-10 39.5 0.0 4.1e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGF99935.1 - 8.4e-06 25.6 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGF99935.1 - 0.063 13.1 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAR1 PF03101.10 EGF99936.1 - 0.011 16.2 0.2 0.018 15.5 0.2 1.3 1 0 0 1 1 1 0 FAR1 DNA-binding domain Dpoe2NT PF12213.3 EGF99942.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal PAP_assoc PF03828.14 EGF99944.1 - 2.6e-17 62.5 0.0 6.2e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EGF99944.1 - 1.5e-05 25.2 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF3599 PF12206.3 EGF99945.1 - 0.03 14.5 0.8 2.2 8.5 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3599) HypA PF01155.14 EGF99945.1 - 5.6 6.6 7.6 7.3 6.3 2.4 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family PM0188 PF11477.3 EGF99948.1 - 0.073 11.8 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Sialyltransferase PMO188 Lsr2 PF11774.3 EGF99949.1 - 0.013 15.4 3.3 0.04 13.8 2.3 1.8 1 0 0 1 1 1 0 Lsr2 Pkinase PF00069.20 EGF99951.1 - 1.8e-64 217.3 0.0 2.1e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGF99951.1 - 2e-43 148.3 0.0 2.3e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGF99951.1 - 0.00038 20.2 0.0 0.00082 19.1 0.0 1.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGF99951.1 - 0.0053 15.7 0.0 0.61 8.9 0.0 2.6 3 0 0 3 3 3 2 Kinase-like RasGAP_C PF03836.10 EGF99952.1 - 9.1e-42 142.1 3.7 9.1e-42 142.1 2.5 3.3 4 0 0 4 4 4 1 RasGAP C-terminus RasGAP PF00616.14 EGF99952.1 - 3.8e-40 137.6 0.1 8.4e-40 136.5 0.1 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EGF99952.1 - 5.8e-13 47.2 46.9 0.011 15.2 0.2 12.2 11 0 0 11 11 11 7 IQ calmodulin-binding motif CH PF00307.26 EGF99952.1 - 1.9e-08 34.3 0.0 6.3e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain NUDIX PF00293.23 EGF99953.1 - 1.9e-08 34.0 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain LRR_4 PF12799.2 EGF99955.1 - 0.00083 18.9 5.9 16 5.2 0.0 5.5 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) AlphaC_N PF08829.5 EGF99956.1 - 0.029 13.7 1.2 0.049 12.9 0.8 1.4 1 0 0 1 1 1 0 Alpha C protein N terminal Terpene_synth_C PF03936.11 EGF99957.1 - 0.084 12.0 0.1 0.1 11.8 0.1 1.0 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain DUF543 PF04418.7 EGF99960.1 - 6.9e-26 90.0 0.3 9.6e-26 89.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Adeno_PVIII PF01310.13 EGF99963.1 - 0.093 12.5 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII XhlA PF10779.4 EGF99965.1 - 0.67 9.9 2.5 1 9.3 1.7 1.2 1 0 0 1 1 1 0 Haemolysin XhlA T4SS PF07996.6 EGF99966.1 - 0.37 10.6 3.5 0.41 10.4 0.1 2.0 2 0 0 2 2 2 0 Type IV secretion system proteins XhlA PF10779.4 EGF99966.1 - 0.43 10.5 1.9 0.66 9.9 1.3 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Sugarporin_N PF11471.3 EGF99966.1 - 7.2 6.3 6.4 0.85 9.3 1.3 1.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Sugarporin_N PF11471.3 EGF99967.1 - 0.0066 16.0 3.6 0.0066 16.0 2.5 1.7 2 0 0 2 2 2 1 Maltoporin periplasmic N-terminal extension Deltaretro_Tax PF05599.6 EGF99967.1 - 0.076 13.3 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Deltaretrovirus Tax protein DUF2360 PF10152.4 EGF99967.1 - 0.15 12.3 1.9 0.22 11.7 0.1 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Cellulose_synt PF03552.9 EGF99969.1 - 0.82 7.8 2.1 8.1 4.6 0.1 2.1 2 0 0 2 2 2 0 Cellulose synthase TFIIA PF03153.8 EGF99970.1 - 0.0017 18.3 22.7 0.0017 18.3 15.8 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EGF99970.1 - 0.48 8.2 38.1 1 7.2 26.4 1.6 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 EGF99970.1 - 2.5 7.2 40.2 0.014 14.6 14.0 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T PPP4R2 PF09184.6 EGF99970.1 - 3 7.3 35.9 8.6 5.8 24.9 1.7 1 0 0 1 1 1 0 PPP4R2 PP28 PF10252.4 EGF99972.1 - 0.73 9.9 3.6 0.33 10.9 0.5 2.0 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Glyco_hydro_18 PF00704.23 EGF99973.1 - 4.6e-59 200.5 3.0 6.1e-59 200.1 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 EGF99973.1 - 0.043 12.9 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 UBN2 PF14223.1 EGF99978.1 - 1.5e-05 24.7 0.2 5.6e-05 22.9 0.0 1.9 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGF99978.1 - 4.4e-05 23.0 0.3 0.00041 19.8 0.0 2.3 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type PYRIN PF02758.11 EGF99978.1 - 0.054 13.2 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain Pkinase PF00069.20 EGF99979.1 - 3.6e-14 52.5 0.0 1.9e-06 27.2 0.1 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGF99979.1 - 3.1e-07 29.7 0.0 0.012 14.6 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase DUF2146 PF10220.4 EGF99980.1 - 0.038 11.9 0.4 0.052 11.5 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) NTP_transferase PF00483.18 EGF99983.1 - 6e-48 163.3 0.0 8.9e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGF99983.1 - 5.4e-11 42.8 0.0 8.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EGF99983.1 - 3.4e-07 29.4 7.0 4.6e-06 25.9 0.7 3.3 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGF99983.1 - 0.0059 16.1 4.8 0.1 12.1 0.1 3.3 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase SRP54 PF00448.17 EGF99983.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IspD PF01128.14 EGF99983.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 EGF99983.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase Alpha_kinase PF02816.13 EGF99984.1 - 2.9e-24 85.7 0.2 3.8e-24 85.3 0.2 1.2 1 0 0 1 1 1 1 Alpha-kinase family Kinetochor_Ybp2 PF08568.5 EGF99985.1 - 7.1e-15 54.3 2.8 7.6e-09 34.3 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin DUF3745 PF12560.3 EGF99985.1 - 0.071 12.7 0.9 0.17 11.5 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3745) FTH PF01827.22 EGF99987.1 - 0.0085 15.7 0.3 0.025 14.1 0.1 1.9 2 0 0 2 2 2 1 FTH domain Not3 PF04065.10 EGF99988.1 - 6e-89 297.3 18.8 6e-89 297.3 13.0 1.7 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EGF99988.1 - 1.1e-37 128.8 8.0 3.9e-37 127.1 5.5 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family UCH PF00443.24 EGF99990.1 - 1.3e-41 142.5 1.0 5.7e-41 140.3 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGF99990.1 - 4.8e-16 59.0 0.1 4.8e-16 59.0 0.0 3.5 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Surface_Ag_2 PF01617.12 EGF99991.1 - 0.048 12.8 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Surface antigen Mo25 PF08569.6 EGF99993.1 - 1.4e-15 57.2 1.6 1.7e-15 56.9 1.1 1.3 1 0 0 1 1 1 1 Mo25-like TUDOR PF00567.19 EGF99994.1 - 0.041 13.7 0.0 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 Tudor domain Chromo PF00385.19 EGF99997.1 - 7.4e-10 38.3 0.7 2.3e-09 36.7 0.5 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Totivirus_coat PF05518.6 EGF99997.1 - 3.6 5.2 4.4 5.2 4.7 3.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein NOA36 PF06524.7 EGF99997.1 - 7.4 5.7 11.3 15 4.7 7.8 1.4 1 0 0 1 1 1 0 NOA36 protein AAA PF00004.24 EGF99998.1 - 3.5e-07 30.5 0.7 1.1e-05 25.6 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGF99998.1 - 0.0024 18.0 0.0 0.0068 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGF99998.1 - 0.0039 18.0 0.4 0.026 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain CDC27 PF09507.5 EGF99998.1 - 0.0043 16.3 11.1 0.0043 16.3 7.7 3.7 3 1 0 3 3 3 1 DNA polymerase subunit Cdc27 AAA_16 PF13191.1 EGF99998.1 - 0.0049 16.8 0.0 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain IPT PF01745.11 EGF99998.1 - 0.017 14.3 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase RuvB_N PF05496.7 EGF99998.1 - 0.021 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 EGF99998.1 - 0.024 13.5 0.0 0.048 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PI-PLC-X PF00388.14 EGG00001.1 - 2.5e-54 182.6 0.0 5.5e-54 181.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EGG00001.1 - 2.1e-35 121.2 0.0 6.5e-35 119.6 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EGG00001.1 - 3.7e-13 49.2 0.3 7.8e-12 45.0 0.0 2.7 1 1 1 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EGG00001.1 - 1.4e-10 40.8 0.0 3.5e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain GDPD PF03009.12 EGG00001.1 - 0.002 17.6 0.0 0.006 16.1 0.0 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_7 PF13499.1 EGG00001.1 - 0.0023 18.0 0.1 0.0075 16.3 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.1 EGG00001.1 - 0.0035 16.9 0.2 0.0092 15.6 0.1 1.7 1 0 0 1 1 1 1 EF hand Bromodomain PF00439.20 EGG00001.1 - 0.04 13.8 0.0 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 Bromodomain EF-hand_6 PF13405.1 EGG00001.1 - 0.1 12.5 0.1 3.9 7.6 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 EGG00001.1 - 0.9 8.9 3.5 2.8 7.4 0.1 3.1 3 0 0 3 3 3 0 EF hand BRO1 PF03097.13 EGG00004.1 - 2.8e-90 302.7 0.6 4.1e-90 302.2 0.4 1.2 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EGG00004.1 - 9.9e-55 185.5 7.0 9.9e-55 185.5 4.9 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF1518 PF07469.7 EGG00005.1 - 6.2 7.0 5.7 9.8 6.4 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1518) ATP_sub_h PF10775.4 EGG00006.1 - 2.1e-16 59.3 0.2 3.2e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h F-box-like PF12937.2 EGG00009.1 - 0.0014 18.3 0.1 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGG00009.1 - 0.021 14.4 0.1 0.063 12.9 0.0 1.9 2 0 0 2 2 2 0 F-box domain ABC_sub_bind PF04392.7 EGG00010.1 - 0.17 10.8 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 ABC transporter substrate binding protein F-box-like PF12937.2 EGG00011.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like SSB PF00436.20 EGG00017.1 - 0.091 12.6 0.3 0.25 11.2 0.0 1.9 1 1 1 2 2 2 0 Single-strand binding protein family NTP_transferase PF00483.18 EGG00018.1 - 3.6e-48 164.0 0.0 5.1e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGG00018.1 - 3.2e-11 43.5 0.0 5.1e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EGG00018.1 - 5.2e-08 32.0 8.2 3e-06 26.4 1.6 3.9 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) IspD PF01128.14 EGG00018.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SRP54 PF00448.17 EGG00018.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CTP_transf_3 PF02348.14 EGG00018.1 - 0.016 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase DUF1541 PF07563.6 EGG00018.1 - 0.14 11.8 3.5 20 4.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) Hexapep_2 PF14602.1 EGG00018.1 - 2.4 7.8 8.3 1.1 8.8 1.6 3.5 4 1 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Ras PF00071.17 EGG00019.1 - 5.6e-44 149.3 0.0 6.5e-44 149.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG00019.1 - 1.9e-16 60.6 0.0 2.6e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGG00019.1 - 5.8e-05 23.0 0.0 7.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGG00019.1 - 5.9e-05 22.5 0.0 8.7e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EGG00019.1 - 0.00012 21.4 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_14 PF13173.1 EGG00019.1 - 0.0036 17.1 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EGG00019.1 - 0.041 13.1 0.0 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.5 EGG00019.1 - 0.069 12.3 0.0 0.14 11.3 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGG00019.1 - 0.083 12.0 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF4477 PF14780.1 EGG00020.1 - 0.00099 18.5 1.8 0.04 13.2 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4477) Fe-ADH PF00465.14 EGG00021.1 - 3.7e-09 35.6 2.2 1.7e-06 26.9 0.4 2.0 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase FAR1 PF03101.10 EGG00024.1 - 6.3e-06 26.6 0.9 6.3e-06 26.6 0.6 2.3 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.6 EGG00024.1 - 0.0082 16.3 0.7 0.0082 16.3 0.5 2.5 2 2 0 2 2 2 1 Transcription factor AFT UBA_4 PF14555.1 EGG00025.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain FliJ PF02050.11 EGG00026.1 - 0.0081 16.2 4.5 0.0081 16.2 3.1 2.1 2 1 0 2 2 1 1 Flagellar FliJ protein PspA_IM30 PF04012.7 EGG00026.1 - 0.01 15.2 1.6 0.02 14.2 1.1 1.4 1 0 0 1 1 1 0 PspA/IM30 family DUF342 PF03961.8 EGG00026.1 - 0.012 14.0 1.6 0.021 13.2 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NPV_P10 PF05531.7 EGG00026.1 - 0.02 15.0 2.4 0.65 10.2 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EGG00026.1 - 0.022 14.5 1.1 0.067 13.0 0.5 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 EGG00026.1 - 0.041 13.9 3.5 0.11 12.6 2.4 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 EGG00026.1 - 0.29 10.9 8.4 0.83 9.4 5.9 1.7 1 1 0 1 1 1 0 Tropomyosin like Prefoldin_2 PF01920.15 EGG00026.1 - 0.62 9.8 6.1 4.2 7.1 0.1 2.6 1 1 1 2 2 2 0 Prefoldin subunit Reo_sigmaC PF04582.7 EGG00026.1 - 1 8.4 6.5 0.1 11.7 1.1 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Med4 PF10018.4 EGG00026.1 - 1 8.6 10.6 6.7 6.0 0.2 3.4 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 SlyX PF04102.7 EGG00026.1 - 2.8 8.3 6.0 7.3 7.0 0.3 3.1 2 1 1 3 3 3 0 SlyX PspB PF06667.7 EGG00026.1 - 4.9 7.1 5.5 14 5.6 0.1 3.0 3 0 0 3 3 3 0 Phage shock protein B DUF4094 PF13334.1 EGG00026.1 - 5.7 7.3 9.1 4.4 7.7 0.1 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4094) LURAP PF14854.1 EGG00027.1 - 0.0018 18.0 1.0 0.0039 16.8 0.6 1.6 1 1 1 2 2 2 1 Leucine rich adaptor protein CCDC155 PF14662.1 EGG00027.1 - 0.0044 16.6 6.5 0.0068 16.0 4.5 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Fez1 PF06818.10 EGG00027.1 - 0.02 14.9 2.2 0.025 14.5 1.5 1.2 1 0 0 1 1 1 0 Fez1 TBPIP PF07106.8 EGG00027.1 - 0.19 11.2 4.0 0.22 11.0 1.6 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tup_N PF08581.5 EGG00027.1 - 0.26 11.5 3.7 0.24 11.6 1.0 2.0 1 1 0 2 2 2 0 Tup N-terminal Spc7 PF08317.6 EGG00027.1 - 0.35 9.4 4.8 0.21 10.1 1.4 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-Q PF13094.1 EGG00027.1 - 0.43 10.5 7.1 0.42 10.6 2.2 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3349 PF11829.3 EGG00030.1 - 0.062 13.7 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) Defensin_4 PF07936.7 EGG00031.1 - 0.2 11.3 5.6 0.41 10.3 0.6 2.8 2 0 0 2 2 2 0 Potassium-channel blocking toxin AUX_IAA PF02309.11 EGG00033.1 - 1.6 8.4 5.9 0.42 10.3 2.2 1.4 2 0 0 2 2 2 0 AUX/IAA family Pox_Ag35 PF03286.9 EGG00034.1 - 0.92 8.9 7.1 1.2 8.5 4.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sec15 PF04091.7 EGG00037.1 - 9.5e-73 245.2 0.0 1.9e-72 244.2 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.4 EGG00037.1 - 0.00019 21.3 0.8 0.00063 19.7 0.5 1.9 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Sec5 PF15469.1 EGG00037.1 - 0.0002 21.1 0.1 0.00055 19.7 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 EGG00037.1 - 0.0082 15.9 0.1 0.1 12.4 0.0 2.6 1 1 1 2 2 2 1 Vps51/Vps67 Sec8_exocyst PF04048.9 EGG00037.1 - 0.029 14.0 1.6 0.065 12.8 1.1 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain FlgH PF02107.11 EGG00038.1 - 0.034 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Flagellar L-ring protein Nol1_Nop2_Fmu PF01189.12 EGG00040.1 - 1.2e-95 320.1 0.0 1.6e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EGG00040.1 - 0.00069 19.6 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EGG00040.1 - 0.0043 16.6 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGG00040.1 - 0.038 13.5 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AAA PF00004.24 EGG00041.1 - 1.8e-92 306.4 0.0 4.6e-47 159.5 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGG00041.1 - 7.7e-14 51.2 0.0 8.1e-07 28.3 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGG00041.1 - 2e-13 50.6 2.4 0.002 18.2 0.0 5.2 3 2 1 4 4 4 3 AAA domain AAA_2 PF07724.9 EGG00041.1 - 3.6e-13 49.7 0.0 2e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EGG00041.1 - 4.6e-11 42.6 0.3 0.00092 18.9 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGG00041.1 - 5.6e-11 42.4 0.0 0.0003 20.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGG00041.1 - 6.7e-11 42.5 2.3 0.00051 20.0 0.0 3.8 3 2 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.1 EGG00041.1 - 2.5e-10 40.4 0.0 0.00041 20.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EGG00041.1 - 2.7e-10 41.1 0.0 0.00024 21.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EGG00041.1 - 6.3e-09 35.2 0.2 0.0014 17.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EGG00041.1 - 2.2e-08 33.7 0.5 0.0028 17.1 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGG00041.1 - 1e-07 31.2 0.0 0.0066 15.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 EGG00041.1 - 1.6e-07 31.4 0.0 0.02 15.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.8 EGG00041.1 - 2.4e-07 29.8 0.1 0.0049 15.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 EGG00041.1 - 3.3e-07 30.6 0.0 0.012 15.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 EGG00041.1 - 1.4e-06 28.0 2.4 0.13 11.8 0.1 4.1 3 1 1 4 4 4 2 NACHT domain AAA_28 PF13521.1 EGG00041.1 - 1.9e-06 27.9 0.0 0.067 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 EGG00041.1 - 3e-06 27.3 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EGG00041.1 - 4.8e-06 26.1 5.8 1.4 8.2 0.1 4.3 2 2 2 4 4 4 2 AAA domain ABC_tran PF00005.22 EGG00041.1 - 5e-06 26.8 0.1 0.31 11.3 0.0 3.6 3 0 0 3 3 3 2 ABC transporter AAA_19 PF13245.1 EGG00041.1 - 5.4e-06 26.0 0.1 0.17 11.6 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain Rad17 PF03215.10 EGG00041.1 - 9.9e-06 24.4 0.0 0.0047 15.6 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein KaiC PF06745.8 EGG00041.1 - 2e-05 23.8 0.4 0.71 8.9 0.0 3.4 2 1 1 3 3 3 2 KaiC ATP-synt_ab PF00006.20 EGG00041.1 - 4.7e-05 22.9 0.0 0.12 11.8 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 EGG00041.1 - 5.5e-05 22.2 0.0 0.056 12.3 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF815) NB-ARC PF00931.17 EGG00041.1 - 8.3e-05 21.5 0.0 0.18 10.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_3 PF07726.6 EGG00041.1 - 8.9e-05 22.0 0.0 0.47 10.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGG00041.1 - 0.00025 20.8 0.0 1.9 8.1 0.0 3.5 2 2 1 3 3 3 1 Archaeal ATPase SKI PF01202.17 EGG00041.1 - 0.00026 20.8 0.0 0.73 9.6 0.0 2.5 2 0 0 2 2 2 2 Shikimate kinase Sigma54_activat PF00158.21 EGG00041.1 - 0.00042 19.8 0.0 0.41 10.1 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 EGG00041.1 - 0.00051 19.9 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Parvo_NS1 PF01057.12 EGG00041.1 - 0.00055 18.8 0.2 0.61 8.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NTPase_1 PF03266.10 EGG00041.1 - 0.00096 18.8 0.1 1.8 8.2 0.0 3.1 2 1 1 3 3 3 1 NTPase Viral_helicase1 PF01443.13 EGG00041.1 - 0.00098 18.7 0.3 0.83 9.1 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 EGG00041.1 - 0.0023 17.5 0.2 1.1 8.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EGG00041.1 - 0.0028 16.9 0.1 1.4 8.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Vps4_C PF09336.5 EGG00041.1 - 0.004 17.0 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.1 EGG00041.1 - 0.0041 16.7 0.0 3.4 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EGG00041.1 - 0.0043 16.8 0.0 2.3 8.0 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EGG00041.1 - 0.0083 15.5 0.8 6.5 6.0 0.0 3.6 3 2 1 4 4 3 0 AAA-like domain PduV-EutP PF10662.4 EGG00041.1 - 0.018 14.5 0.0 7.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.13 EGG00041.1 - 0.05 13.2 0.0 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein KTI12 PF08433.5 EGG00041.1 - 0.055 12.6 0.0 3.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ADK PF00406.17 EGG00041.1 - 0.077 12.8 0.1 9 6.1 0.0 2.5 2 0 0 2 2 2 0 Adenylate kinase SRPRB PF09439.5 EGG00041.1 - 0.11 11.6 0.6 16 4.6 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF2075 PF09848.4 EGG00041.1 - 0.13 11.1 0.0 14 4.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) G-patch PF01585.18 EGG00042.1 - 1.5e-09 37.5 0.5 6.2e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 G-patch domain Glyco_transf_43 PF03360.11 EGG00042.1 - 0.84 9.1 1.7 0.69 9.4 0.1 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 43 SpoIIIAH PF12685.2 EGG00042.1 - 2.8 7.3 5.4 12 5.3 0.3 3.0 3 0 0 3 3 3 0 SpoIIIAH-like protein Cyclin_N PF00134.18 EGG00049.1 - 1.7e-13 50.2 1.9 2e-13 50.0 0.4 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EGG00049.1 - 0.0005 19.8 0.7 0.0018 18.0 0.5 2.0 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 EGG00049.1 - 0.0061 16.4 0.6 1.5 8.7 0.0 2.9 3 0 0 3 3 3 2 Cyclin, C-terminal domain DnaJ PF00226.26 EGG00050.1 - 4.3e-08 32.7 0.2 5e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EGG00050.1 - 0.00071 19.3 0.0 0.00081 19.1 0.0 1.1 1 0 0 1 1 1 1 Pam16 Rota_VP2 PF05087.7 EGG00051.1 - 0.068 11.0 0.8 0.098 10.5 0.5 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF2413 PF10310.4 EGG00051.1 - 3.4 6.3 12.6 0.043 12.6 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Bot1p PF12298.3 EGG00053.1 - 1.1e-15 57.9 2.4 3.4e-10 40.1 0.6 2.6 1 1 1 2 2 2 2 Eukaryotic mitochondrial regulator protein Glyco_hydro_18 PF00704.23 EGG00054.1 - 2e-62 211.6 0.2 2.3e-62 211.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ING PF12998.2 EGG00055.1 - 1e-09 38.5 0.6 7.2e-09 35.8 0.4 2.0 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EGG00055.1 - 4.2e-09 35.9 9.0 8.5e-09 34.9 6.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EGG00055.1 - 6.7e-05 22.9 0.7 0.00014 21.9 0.5 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-RING-like PF08746.6 EGG00055.1 - 0.041 13.8 2.7 0.074 13.0 1.9 1.4 1 0 0 1 1 1 0 RING-like domain Toxin_34 PF08396.5 EGG00055.1 - 0.059 13.9 2.9 0.11 13.0 2.0 1.4 1 0 0 1 1 1 0 Spider toxin omega agatoxin/Tx1 family Pec_lyase_C PF00544.14 EGG00056.1 - 2.7e-19 69.4 4.9 4.7e-19 68.6 3.4 1.3 1 0 0 1 1 1 1 Pectate lyase RasGAP PF00616.14 EGG00057.1 - 1e-35 123.1 0.0 2.2e-35 122.1 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EGG00057.1 - 1.3e-07 31.6 0.0 4.7e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DUF2153 PF09921.4 EGG00057.1 - 0.059 12.9 0.1 0.5 9.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) DUF1682 PF07946.9 EGG00059.1 - 0.67 8.7 11.9 0.78 8.5 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4407 PF14362.1 EGG00059.1 - 1.5 7.7 5.4 1.7 7.5 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3987 PF13148.1 EGG00059.1 - 3.1 6.2 10.2 3.7 6.0 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Daxx PF03344.10 EGG00059.1 - 7 4.9 11.6 7.7 4.8 8.1 1.0 1 0 0 1 1 1 0 Daxx Family Pkinase PF00069.20 EGG00060.1 - 1.2e-50 172.1 0.0 2.1e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG00060.1 - 2.5e-44 151.2 0.0 3.6e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG00060.1 - 0.00011 22.0 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGG00060.1 - 0.011 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FTA4 PF13093.1 EGG00061.1 - 0.00087 18.7 1.4 0.00093 18.6 0.9 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1903 PF08991.5 EGG00064.1 - 3.2e-16 59.2 10.7 3.6e-16 59.0 7.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EGG00064.1 - 5.3 7.0 13.8 1.8 8.6 6.8 1.9 2 0 0 2 2 2 0 CHCH domain FB_lectin PF07367.6 EGG00065.1 - 0.022 14.3 1.7 0.025 14.2 0.0 1.8 2 0 0 2 2 2 0 Fungal fruit body lectin SOBP PF15279.1 EGG00065.1 - 1 9.6 11.2 2.5 8.4 7.8 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein CSTF_C PF14304.1 EGG00065.1 - 2.2 7.6 8.0 0.15 11.3 0.3 2.9 4 0 0 4 4 4 0 Transcription termination and cleavage factor C-terminal eIF-3c_N PF05470.7 EGG00065.1 - 2.8 5.9 14.1 4.7 5.1 9.7 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.7 EGG00065.1 - 7.9 4.2 29.9 13 3.5 20.7 1.4 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.7 EGG00065.1 - 7.9 6.2 16.6 16 5.2 11.5 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Fes1 PF08609.5 EGG00066.1 - 6.8e-15 55.3 0.9 1.7e-14 54.0 0.2 1.9 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EGG00066.1 - 6.1e-05 23.2 0.0 0.011 16.0 0.0 2.5 2 1 1 3 3 3 2 HEAT repeats Arm PF00514.18 EGG00066.1 - 0.0037 17.0 0.0 0.06 13.1 0.0 2.4 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 EGG00066.1 - 0.074 11.3 1.2 0.089 11.0 0.8 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit HEAT PF02985.17 EGG00066.1 - 0.15 12.2 0.0 25 5.3 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat Dicistro_VP4 PF11492.3 EGG00067.1 - 0.09 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 Daxx PF03344.10 EGG00068.1 - 0.74 8.2 26.0 1 7.7 18.0 1.2 1 0 0 1 1 1 0 Daxx Family PI3K_1B_p101 PF10486.4 EGG00068.1 - 5.4 4.4 14.3 8.1 3.8 9.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CBFD_NFYB_HMF PF00808.18 EGG00069.1 - 3e-11 43.1 0.0 7.6e-09 35.5 0.0 2.2 1 1 1 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GTP_EFTU PF00009.22 EGG00070.1 - 1.3e-38 132.3 0.0 2.1e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EGG00070.1 - 7e-38 128.5 0.3 1.8e-37 127.2 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EGG00070.1 - 5.2e-10 39.3 0.9 1.5e-09 37.8 0.7 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGG00070.1 - 0.0054 16.6 0.0 0.019 14.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase zf-CGNR PF11706.3 EGG00070.1 - 0.29 10.6 2.0 0.5 9.9 1.4 1.4 1 0 0 1 1 1 0 CGNR zinc finger WLM PF08325.5 EGG00074.1 - 5.5e-23 81.8 9.0 2.2e-18 66.7 0.1 3.2 2 2 1 3 3 3 2 WLM domain zf-Sec23_Sec24 PF04810.10 EGG00074.1 - 0.057 12.9 1.1 0.12 11.9 0.8 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger DUF45 PF01863.12 EGG00074.1 - 0.49 10.1 0.0 0.49 10.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF45 hNIFK_binding PF12196.3 EGG00074.1 - 1.2 8.5 9.7 3.3 7.1 2.0 2.8 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Pyr_redox_2 PF07992.9 EGG00076.1 - 3.4e-43 147.8 5.6 1.1e-41 142.9 3.9 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EGG00076.1 - 9.4e-37 125.4 2.1 8e-36 122.4 0.7 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EGG00076.1 - 1.1e-25 89.7 1.7 4.1e-19 68.7 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGG00076.1 - 6.7e-14 52.4 0.0 8e-10 39.1 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGG00076.1 - 6.3e-12 45.3 0.1 1.1e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGG00076.1 - 3.6e-09 35.5 0.8 7.7e-05 21.3 0.5 3.2 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.1 EGG00076.1 - 1.1e-06 28.5 0.9 3.1e-06 27.1 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGG00076.1 - 1.6e-06 27.2 12.6 2.6e-05 23.2 2.5 3.4 3 1 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.12 EGG00076.1 - 1.6e-06 27.3 0.9 2.6e-06 26.7 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EGG00076.1 - 2.3e-06 26.7 3.2 7.3e-06 25.0 2.1 1.8 1 1 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EGG00076.1 - 1.7e-05 24.5 0.7 0.025 14.2 0.0 2.5 2 1 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EGG00076.1 - 3.5e-05 22.8 2.0 0.00025 20.0 0.9 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.1 EGG00076.1 - 7.4e-05 21.8 0.0 0.0076 15.1 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EGG00076.1 - 0.00019 21.0 0.0 0.26 10.8 0.0 2.7 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EGG00076.1 - 0.002 17.1 0.0 0.026 13.4 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 EGG00076.1 - 0.0027 16.8 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EGG00076.1 - 0.0036 16.4 0.9 0.32 9.9 0.3 2.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 EGG00076.1 - 0.0053 16.9 0.4 0.41 10.9 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding XdhC_C PF13478.1 EGG00076.1 - 0.014 15.6 0.1 2 8.7 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.18 EGG00076.1 - 0.04 13.6 0.2 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EGG00076.1 - 0.38 11.2 2.0 8.6 6.8 0.2 2.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TOM13 PF08219.6 EGG00078.1 - 2.7e-12 46.2 5.0 1.2e-11 44.2 3.5 2.1 1 1 0 1 1 1 1 Outer membrane protein TOM13 DUF3721 PF12518.3 EGG00079.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function ABC2_membrane PF01061.19 EGG00080.1 - 2.6e-32 111.6 21.7 2.6e-32 111.6 15.1 2.7 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 EGG00080.1 - 5.2e-27 94.8 0.1 9.1e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGG00080.1 - 2.8e-09 37.3 0.1 3.6e-08 33.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EGG00080.1 - 0.00011 21.3 25.8 0.00011 21.3 17.9 2.2 2 1 0 2 2 2 1 ABC-2 family transporter protein hEGF PF12661.2 EGG00080.1 - 0.00046 20.0 27.5 0.0025 17.7 1.3 4.7 4 0 0 4 4 4 2 Human growth factor-like EGF AAA_15 PF13175.1 EGG00080.1 - 0.0013 17.9 0.0 0.98 8.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.1 EGG00080.1 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EGG00080.1 - 0.0031 16.7 0.1 0.0076 15.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGG00080.1 - 0.0042 16.5 0.1 0.0097 15.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EGG00080.1 - 0.0098 15.1 0.3 0.35 10.0 0.1 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EGG00080.1 - 0.051 12.9 0.1 1.6 8.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EGG00080.1 - 0.15 11.9 0.0 0.8 9.6 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF4003 PF13170.1 EGG00080.1 - 0.16 11.1 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) EGF_2 PF07974.8 EGG00080.1 - 0.17 12.0 31.3 0.3 11.2 0.9 3.7 3 0 0 3 3 3 0 EGF-like domain HTH_22 PF13309.1 EGG00080.1 - 0.2 11.4 0.0 0.45 10.2 0.0 1.5 1 0 0 1 1 1 0 HTH domain Rad17 PF03215.10 EGG00080.1 - 0.24 10.0 0.0 0.51 8.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 EGG00080.1 - 0.24 11.6 0.0 0.47 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain EGF PF00008.22 EGG00080.1 - 0.26 11.3 33.8 0.13 12.2 7.3 5.0 5 0 0 5 5 5 0 EGF-like domain Laminin_EGF PF00053.19 EGG00080.1 - 3.5 7.6 34.5 0.21 11.5 6.6 3.8 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) OTU PF02338.14 EGG00082.1 - 0.00012 22.6 0.0 0.0002 21.9 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGG00082.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C65 Otubain SSXRD PF09514.5 EGG00082.1 - 2.2 7.6 4.3 12 5.2 0.1 2.9 3 0 0 3 3 3 0 SSXRD motif UPF0227 PF05728.7 EGG00083.1 - 0.052 13.2 0.3 0.12 12.0 0.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PPR_2 PF13041.1 EGG00085.1 - 6e-06 26.1 0.0 0.036 14.0 0.0 3.4 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.1 EGG00085.1 - 0.0014 18.7 0.9 2.6 8.5 0.1 4.8 4 1 0 4 4 4 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 EGG00085.1 - 0.042 13.3 0.0 4.2 6.9 0.0 2.6 2 0 0 2 2 2 0 PPR repeat PPR PF01535.15 EGG00085.1 - 0.08 12.9 0.1 19 5.5 0.0 4.3 5 0 0 5 5 5 0 PPR repeat ARD PF03079.9 EGG00087.1 - 2.8e-29 102.0 1.6 3.6e-29 101.7 1.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EGG00087.1 - 0.0091 15.4 0.3 0.026 14.0 0.1 1.9 3 0 0 3 3 3 1 Cupin domain RRM_1 PF00076.17 EGG00088.1 - 1.3e-17 63.1 0.0 6.3e-10 38.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG00088.1 - 7.5e-15 54.6 0.0 4.3e-08 33.0 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG00088.1 - 3.1e-07 30.1 0.0 9.9e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EGG00088.1 - 0.0019 17.7 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 Calcipressin Alpha_kinase PF02816.13 EGG00089.1 - 2.2e-05 24.1 1.0 4.1e-05 23.3 0.5 1.7 1 1 1 2 2 2 1 Alpha-kinase family bZIP_1 PF00170.16 EGG00092.1 - 0.00041 20.2 12.6 0.001 18.9 8.7 1.7 1 1 0 1 1 1 1 bZIP transcription factor Mem_trans PF03547.13 EGG00092.1 - 0.028 12.7 1.6 0.037 12.3 1.1 1.1 1 0 0 1 1 1 0 Membrane transport protein bZIP_2 PF07716.10 EGG00092.1 - 0.068 13.0 16.9 1.5 8.6 10.8 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Band_3_cyto PF07565.8 EGG00092.1 - 0.1 12.1 1.8 0.13 11.7 1.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SEEEED PF14797.1 EGG00092.1 - 0.78 9.8 9.3 1.1 9.4 6.4 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex PRKCSH PF07915.8 EGG00093.1 - 7.3e-11 42.7 0.0 7.3e-11 42.7 0.0 3.5 3 2 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EGG00093.1 - 0.007 15.8 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein RabGAP-TBC PF00566.13 EGG00096.1 - 4.8e-31 107.8 7.5 4.3e-13 49.2 0.1 3.9 3 1 0 3 3 3 3 Rab-GTPase-TBC domain Barttin PF15462.1 EGG00097.1 - 0.051 13.2 7.2 0.084 12.5 5.0 1.3 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) vWF_A PF12450.3 EGG00098.1 - 0.07 12.8 0.4 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 von Willebrand factor VLPT PF07122.6 EGG00099.1 - 0.099 12.3 0.8 0.17 11.5 0.5 1.4 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) F-box-like PF12937.2 EGG00102.1 - 0.0011 18.6 0.1 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like ANF_receptor PF01094.23 EGG00102.1 - 0.09 11.5 0.0 0.31 9.7 0.0 1.8 2 0 0 2 2 2 0 Receptor family ligand binding region Glyco_hydro_44 PF12891.2 EGG00103.1 - 0.034 13.6 0.1 2.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Glycoside hydrolase family 44 Birna_VP4 PF01768.11 EGG00103.1 - 0.058 12.4 0.0 0.084 11.9 0.0 1.1 1 0 0 1 1 1 0 Birnavirus VP4 protein CPG4 PF15481.1 EGG00104.1 - 0.007 16.6 0.5 0.017 15.4 0.2 1.7 1 1 0 1 1 1 1 Chondroitin proteoglycan 4 Mating_C PF12737.2 EGG00109.1 - 0.018 13.9 6.3 0.029 13.2 4.4 1.3 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Synaptobrevin PF00957.16 EGG00112.1 - 1.2e-34 117.7 0.7 1.3e-34 117.6 0.5 1.0 1 0 0 1 1 1 1 Synaptobrevin RabGAP-TBC PF00566.13 EGG00113.1 - 0.031 13.7 0.2 0.055 12.9 0.1 1.4 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Trypan_PARP PF05887.6 EGG00115.1 - 0.36 10.6 23.0 0.23 11.2 14.4 1.8 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Peptidase_S30 PF01577.11 EGG00115.1 - 4.1 6.7 12.1 7.5 5.8 8.4 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease PAS_9 PF13426.1 EGG00118.1 - 3.7e-20 72.2 0.0 2.1e-18 66.5 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EGG00118.1 - 0.0018 18.0 0.0 0.0081 15.9 0.0 2.0 2 0 0 2 2 2 1 PAS fold SH3BGR PF04908.10 EGG00118.1 - 0.05 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein NAC PF01849.13 EGG00119.1 - 2.2e-17 62.2 0.1 3.8e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 NAC domain Aminotran_3 PF00202.16 EGG00120.1 - 4.8e-94 314.9 0.1 6.7e-94 314.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGG00120.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2623 PF11115.3 EGG00120.1 - 0.0046 16.8 0.0 0.086 12.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2623) Serine_rich PF08824.5 EGG00120.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Serine rich protein interaction domain Ribosomal_L11_N PF03946.9 EGG00121.1 - 4.3e-24 83.7 0.0 6.6e-24 83.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EGG00121.1 - 3.8e-20 71.7 0.1 5.7e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Late_protein_L2 PF00513.13 EGG00121.1 - 0.028 13.2 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Late Protein L2 Ctf8 PF09696.5 EGG00122.1 - 8.1e-21 74.0 0.0 9.7e-21 73.7 0.0 1.1 1 0 0 1 1 1 1 Ctf8 LEH PF07858.7 EGG00123.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Glycogen_syn PF05693.8 EGG00124.1 - 0 1126.5 0.0 0 1126.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EGG00124.1 - 7.5e-08 31.9 0.0 0.0001 21.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EGG00124.1 - 1.3e-06 28.0 0.1 3.8e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EGG00124.1 - 1.1e-05 25.5 0.0 2.5e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF1978 PF09321.5 EGG00124.1 - 0.056 12.8 0.2 0.21 11.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) Gly-zipper_OmpA PF13436.1 EGG00125.1 - 0.11 12.1 4.5 0.14 11.7 3.1 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Annexin PF00191.15 EGG00128.1 - 0.063 13.1 0.3 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Annexin EST1_DNA_bind PF10373.4 EGG00129.1 - 0.011 15.0 0.9 0.011 14.9 0.6 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Aconitase_C PF00694.14 EGG00129.1 - 0.057 13.5 0.6 0.061 13.4 0.4 1.0 1 0 0 1 1 1 0 Aconitase C-terminal domain DUF1183 PF06682.7 EGG00130.1 - 8.6e-15 55.1 0.1 1.4e-13 51.1 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) Tsg PF04668.7 EGG00130.1 - 4.6 7.4 6.9 1.1 9.5 0.5 2.5 1 1 2 3 3 3 0 Twisted gastrulation (Tsg) protein conserved region PHY PF00360.15 EGG00131.1 - 3.8e-25 88.0 0.0 1.6e-24 86.0 0.0 2.0 2 1 0 2 2 2 1 Phytochrome region HATPase_c PF02518.21 EGG00131.1 - 2.6e-24 85.0 0.3 5.2e-24 84.1 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGG00131.1 - 4.2e-18 65.3 0.1 1.4e-17 63.7 0.1 1.8 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EGG00131.1 - 5.1e-14 52.0 1.4 1.2e-13 50.7 1.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EGG00131.1 - 6e-14 52.4 0.0 1.4e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain PAS_2 PF08446.6 EGG00131.1 - 8.2e-08 32.6 0.1 3.8e-07 30.5 0.0 2.2 1 0 0 1 1 1 1 PAS fold Claudin_3 PF06653.6 EGG00132.1 - 0.042 13.5 3.6 0.075 12.7 2.5 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Gemini_mov PF01708.11 EGG00132.1 - 4 7.0 5.2 28 4.3 1.5 3.2 3 1 1 4 4 4 0 Geminivirus putative movement protein SLT PF01464.15 EGG00134.1 - 5.4e-14 51.7 0.0 1.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain DUF3449 PF11931.3 EGG00135.1 - 9.8e-74 247.1 1.9 2.3e-72 242.6 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-met PF12874.2 EGG00135.1 - 1.6e-07 31.2 8.8 2.8e-06 27.3 2.5 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.3 EGG00135.1 - 4.6e-06 26.0 1.4 6.5e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 EGG00135.1 - 2.4e-05 24.3 2.8 2.4e-05 24.3 2.0 3.0 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGG00135.1 - 0.0032 17.5 1.2 0.11 12.6 0.1 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Hormone_3 PF00159.13 EGG00135.1 - 0.013 15.5 0.2 0.039 13.9 0.1 1.8 1 0 0 1 1 1 0 Pancreatic hormone peptide DUF951 PF06107.6 EGG00135.1 - 0.036 13.5 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-DBF PF07535.7 EGG00135.1 - 0.056 13.1 5.1 0.31 10.7 0.2 3.0 3 0 0 3 3 3 0 DBF zinc finger Apc3 PF12895.2 EGG00137.1 - 2.6e-05 24.2 0.1 3.9e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 SRP72 PF08492.7 EGG00137.1 - 0.00037 20.7 12.0 0.00037 20.7 8.3 2.6 1 1 1 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.1 EGG00137.1 - 0.016 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGG00137.1 - 0.018 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 EGG00137.1 - 0.023 14.5 0.2 0.055 13.4 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGG00137.1 - 0.044 13.6 0.4 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGG00137.1 - 0.081 13.5 0.0 0.16 12.7 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat NARP1 PF12569.3 EGG00137.1 - 0.1 11.3 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 EGG00137.1 - 0.13 12.6 0.1 0.35 11.2 0.1 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat Asp-B-Hydro_N PF05279.6 EGG00138.1 - 2.4 7.9 22.4 3.2 7.5 15.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Daxx PF03344.10 EGG00138.1 - 7.9 4.8 24.7 8.5 4.7 17.1 1.0 1 0 0 1 1 1 0 Daxx Family TAF4 PF05236.9 EGG00138.1 - 8.8 5.5 21.8 11 5.2 15.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RRF PF01765.14 EGG00140.1 - 3e-35 121.1 1.4 3.2e-35 121.0 0.9 1.0 1 0 0 1 1 1 1 Ribosome recycling factor 14-3-3 PF00244.15 EGG00140.1 - 0.0012 17.9 1.2 0.0018 17.3 0.9 1.2 1 0 0 1 1 1 1 14-3-3 protein DUF3602 PF12223.3 EGG00141.1 - 1.2e-15 57.5 15.2 6.9e-06 26.3 0.7 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DUF4407 PF14362.1 EGG00141.1 - 0.11 11.4 0.2 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.6 EGG00143.1 - 0.001 18.9 0.7 0.0027 17.5 0.4 1.8 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 EGG00143.1 - 0.0018 18.1 1.4 0.0018 18.1 1.0 1.8 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 EGG00143.1 - 0.0055 16.2 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.6 EGG00143.1 - 0.0097 15.9 1.7 0.012 15.6 0.4 1.7 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Bacillus_HBL PF05791.6 EGG00143.1 - 0.014 14.7 3.2 0.18 11.1 0.6 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4164 PF13747.1 EGG00143.1 - 0.092 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) SH3_1 PF00018.23 EGG00144.1 - 4.2e-21 74.0 0.0 4.7e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EGG00144.1 - 1.7e-16 59.5 0.0 2.5e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EGG00144.1 - 9.1e-15 53.9 0.6 6e-08 32.0 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 EGG00144.1 - 8.5e-11 41.6 0.5 8.5e-11 41.6 0.3 1.8 2 0 0 2 2 2 1 PX domain SIN1 PF05422.7 EGG00146.1 - 1.2e-36 126.3 0.1 6.2e-28 97.5 0.0 2.3 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) RA PF00788.18 EGG00146.1 - 0.099 13.1 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain HTH_DeoR PF08220.7 EGG00147.1 - 0.00025 20.5 2.0 1.9 8.0 0.0 3.6 3 0 0 3 3 3 3 DeoR-like helix-turn-helix domain Trns_repr_metal PF02583.12 EGG00147.1 - 0.011 15.9 0.5 12 6.1 0.0 3.1 3 0 0 3 3 3 0 Metal-sensitive transcriptional repressor DUF2839 PF10999.3 EGG00147.1 - 0.013 15.5 1.7 6.6 6.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) ATP-synt_G PF04718.10 EGG00147.1 - 0.15 12.7 0.0 27 5.4 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ATP synthase g subunit MutL_C PF08676.6 EGG00148.1 - 0.00058 19.4 0.0 0.0053 16.3 0.1 2.3 2 0 0 2 2 2 1 MutL C terminal dimerisation domain Bud13 PF09736.4 EGG00151.1 - 2.9e-45 154.0 2.9 2.9e-45 154.0 2.0 3.1 1 1 2 3 3 3 1 Pre-mRNA-splicing factor of RES complex Frataxin_Cyay PF01491.11 EGG00154.1 - 8.6e-31 105.9 0.0 1.1e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain dCMP_cyt_deam_1 PF00383.17 EGG00155.1 - 0.001 18.6 0.1 0.0018 17.9 0.1 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region ComZ PF10815.3 EGG00155.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 ComZ S1 PF00575.18 EGG00156.1 - 3.2e-10 39.9 0.1 8.1e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Interferon PF00143.14 EGG00156.1 - 0.055 13.3 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Interferon alpha/beta domain OB_NTP_bind PF07717.11 EGG00157.1 - 1.4e-31 108.6 0.0 2.4e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGG00157.1 - 6.1e-28 96.8 0.1 1.2e-27 95.8 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGG00157.1 - 1.8e-12 46.9 0.0 4.6e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cys_Met_Meta_PP PF01053.15 EGG00158.1 - 2.5e-119 398.0 0.0 3.7e-119 397.4 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGG00158.1 - 4.3e-06 25.9 0.0 5.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGG00158.1 - 0.00012 20.9 0.0 0.00019 20.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGG00158.1 - 0.0016 17.6 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase FA_desaturase PF00487.19 EGG00159.1 - 6.5e-37 127.3 15.5 7.9e-37 127.0 10.7 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Rad17 PF03215.10 EGG00160.1 - 1.3e-47 162.7 2.8 5.9e-35 120.9 0.4 2.4 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EGG00160.1 - 0.00077 19.6 0.1 0.016 15.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGG00160.1 - 0.0023 17.9 0.2 0.0086 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EGG00160.1 - 0.036 13.7 0.2 0.78 9.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 EGG00160.1 - 0.038 13.0 0.1 0.091 11.8 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin Peptidase_S10 PF00450.17 EGG00161.1 - 3.1e-75 253.9 4.3 1.7e-45 155.9 0.3 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase Thaumatin PF00314.12 EGG00162.1 - 1.3e-18 67.2 3.8 1.5e-18 67.0 2.6 1.1 1 0 0 1 1 1 1 Thaumatin family MNSV_P7B PF06692.6 EGG00162.1 - 0.12 12.1 0.8 6.4 6.6 0.1 2.4 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein SHMT PF00464.14 EGG00163.1 - 9.1e-175 580.7 0.0 1.1e-174 580.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EGG00163.1 - 0.036 13.2 0.0 0.064 12.3 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase NTP_transferase PF00483.18 EGG00170.1 - 1.1e-48 165.7 0.0 1.5e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGG00170.1 - 1.6e-11 44.5 0.0 2.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EGG00170.1 - 9.8e-08 31.1 8.8 5.9e-06 25.5 1.6 3.9 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGG00170.1 - 0.017 14.7 1.2 0.017 14.7 0.8 3.1 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 EGG00170.1 - 0.02 14.3 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 EGG00170.1 - 0.028 14.0 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase SRP54 PF00448.17 EGG00170.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF1541 PF07563.6 EGG00170.1 - 0.19 11.4 1.3 20 4.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) DnaJ PF00226.26 EGG00171.1 - 4e-05 23.2 0.2 0.0033 17.1 0.1 3.9 2 1 0 2 2 2 1 DnaJ domain DUF1394 PF07159.7 EGG00172.1 - 0.00047 19.3 0.1 0.00091 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) DnaJ PF00226.26 EGG00172.1 - 0.0018 17.9 0.3 0.0077 15.9 0.2 2.1 1 0 0 1 1 1 1 DnaJ domain AKNA PF12443.3 EGG00172.1 - 0.033 14.2 0.6 0.11 12.5 0.4 1.9 1 0 0 1 1 1 0 AT-hook-containing transcription factor TMF_TATA_bd PF12325.3 EGG00172.1 - 0.85 9.3 8.8 3.5 7.3 0.4 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Syntaxin-6_N PF09177.6 EGG00172.1 - 4.1 7.8 6.7 0.59 10.5 0.3 2.8 3 2 0 3 3 3 0 Syntaxin 6, N-terminal zf-CCHC PF00098.18 EGG00174.1 - 0.0051 16.6 2.5 0.0051 16.6 1.7 3.4 3 1 0 3 3 3 2 Zinc knuckle Rad50_zn_hook PF04423.9 EGG00174.1 - 0.01 15.2 3.4 0.011 15.1 0.3 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-CCHC_4 PF14392.1 EGG00174.1 - 0.031 13.9 6.8 0.63 9.7 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGG00174.1 - 0.034 13.8 12.3 0.064 12.9 1.2 2.9 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.1 EGG00174.1 - 0.064 12.7 0.9 2.3 7.7 0.0 2.7 2 0 0 2 2 2 0 Zinc knuckle Coiled PF05710.7 EGG00174.1 - 0.088 13.2 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 Coiled coil Mut7-C PF01927.11 EGG00174.1 - 0.66 9.9 3.2 11 6.0 1.5 2.2 2 0 0 2 2 2 0 Mut7-C RNAse domain zinc-ribbons_6 PF07191.7 EGG00174.1 - 3.2 7.6 12.2 7 6.5 0.4 3.2 3 0 0 3 3 3 0 zinc-ribbons Zn-ribbon_8 PF09723.5 EGG00174.1 - 6.4 6.8 9.2 16 5.5 0.3 3.4 3 0 0 3 3 3 0 Zinc ribbon domain DnaJ_CXXCXGXG PF00684.14 EGG00174.1 - 8.4 6.5 18.3 66 3.6 10.0 2.9 2 1 0 2 2 2 0 DnaJ central domain Sec61_beta PF03911.11 EGG00175.1 - 8.2e-15 54.3 0.0 1.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Sec61beta family DUF2474 PF10617.4 EGG00175.1 - 0.067 12.8 0.7 0.14 11.7 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2474) ING PF12998.2 EGG00176.1 - 8.6e-15 54.9 1.5 8.6e-15 54.9 1.0 2.7 1 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Aminotran_1_2 PF00155.16 EGG00177.1 - 1.5e-55 188.6 0.0 1.9e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGG00177.1 - 1.8e-06 27.3 0.0 2.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pollen_allerg_1 PF01357.16 EGG00179.1 - 0.00014 21.6 0.7 0.00014 21.6 0.5 1.9 2 0 0 2 2 2 1 Pollen allergen Barwin PF00967.12 EGG00179.1 - 0.0042 16.7 3.8 0.011 15.3 1.1 2.3 2 1 0 2 2 2 1 Barwin family DPBB_1 PF03330.13 EGG00179.1 - 0.046 13.7 0.8 0.42 10.6 0.1 2.7 3 1 0 3 3 3 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF4340 PF14238.1 EGG00179.1 - 0.052 13.2 0.1 0.086 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4340) Ribosomal_L32e PF01655.13 EGG00181.1 - 1.7e-48 163.2 0.6 2e-48 163.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 PLA2_B PF01735.13 EGG00182.1 - 9.3e-58 195.5 7.5 2.4e-40 138.1 2.6 4.0 2 2 1 3 3 3 3 Lysophospholipase catalytic domain DUF2841 PF11001.3 EGG00183.1 - 1.3e-37 128.5 0.1 2.3e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) UMP1 PF05348.6 EGG00185.1 - 7.5e-23 80.9 0.1 9e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 NARP1 PF12569.3 EGG00186.1 - 1.9e-120 403.0 4.1 4.6e-120 401.8 2.8 1.6 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 EGG00186.1 - 2.8e-12 46.8 13.4 0.0036 17.5 0.5 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGG00186.1 - 4.7e-09 35.7 18.6 0.00055 19.5 0.1 5.6 6 0 0 6 6 6 2 TPR repeat TPR_16 PF13432.1 EGG00186.1 - 1.2e-06 28.9 23.3 1.9 9.2 0.4 6.3 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGG00186.1 - 1.6e-06 28.2 20.0 0.039 14.6 0.8 6.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGG00186.1 - 5.6e-06 25.8 14.3 0.071 13.0 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGG00186.1 - 0.00012 21.4 9.6 0.4 10.3 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGG00186.1 - 0.0015 18.5 5.8 1.4 9.3 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG00186.1 - 0.038 13.8 15.2 1.2 9.1 0.1 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGG00186.1 - 0.65 9.9 17.6 2 8.4 0.7 6.1 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGG00186.1 - 0.67 9.8 12.1 1.1 9.1 0.3 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGG00186.1 - 0.88 9.5 8.4 18 5.3 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGG00186.1 - 4.1 8.0 14.4 1e+02 3.7 0.2 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat NARP1 PF12569.3 EGG00187.1 - 0.0055 15.5 0.8 0.0065 15.2 0.0 1.5 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 Pkinase PF00069.20 EGG00188.1 - 3.8e-31 108.2 0.0 4.1e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG00188.1 - 5.8e-21 74.7 0.0 6.4e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGG00188.1 - 1.1e-08 34.3 0.0 1.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGG00188.1 - 0.0045 16.5 0.0 0.0057 16.2 0.0 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pox_A14 PF05767.7 EGG00191.1 - 0.63 10.0 4.5 1.2 9.1 0.9 2.5 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 DUF3188 PF11384.3 EGG00191.1 - 1.8 8.2 4.5 7.5 6.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) Colicin_V PF02674.11 EGG00191.1 - 5.6 6.8 10.9 7.2 6.4 1.5 2.1 2 0 0 2 2 2 0 Colicin V production protein zf-MIZ PF02891.15 EGG00192.1 - 5.6e-13 48.1 0.0 1.2e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EGG00192.1 - 0.00018 20.9 0.0 0.00055 19.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit ABC_membrane_2 PF06472.10 EGG00193.1 - 6.3e-96 320.8 8.5 7.9e-96 320.4 5.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGG00193.1 - 5.6e-15 55.8 0.0 1.5e-14 54.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EGG00193.1 - 0.0048 16.8 0.0 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGG00193.1 - 0.0054 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGG00193.1 - 0.0059 17.4 0.0 0.017 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGG00193.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EGG00193.1 - 0.011 16.0 0.0 0.033 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 EGG00193.1 - 0.019 14.2 0.0 4.9 6.3 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGG00193.1 - 0.025 14.0 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 EGG00193.1 - 0.026 14.7 0.1 0.052 13.7 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGG00193.1 - 0.065 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGG00193.1 - 0.075 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGG00193.1 - 0.13 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sad1_UNC PF07738.8 EGG00195.1 - 2.5e-23 82.3 0.0 3.1e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Ribophorin_I PF04597.9 EGG00196.1 - 3.4e-80 269.6 0.0 4.3e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Ribophorin I HMG-CoA_red PF00368.13 EGG00197.1 - 1.5e-157 524.0 3.8 2e-157 523.6 2.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 EGG00197.1 - 2e-16 59.7 1.9 5.6e-16 58.3 1.3 1.7 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EGG00197.1 - 1.5e-10 39.7 3.2 4.2e-10 38.2 0.9 2.1 2 0 0 2 2 2 1 Patched family Tox-GHH PF15636.1 EGG00197.1 - 0.26 10.9 0.0 0.69 9.5 0.0 1.7 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin PAPA-1 PF04795.7 EGG00198.1 - 1.7e-14 54.2 1.0 1.7e-14 54.2 0.7 2.6 2 1 0 2 2 2 1 PAPA-1-like conserved region Polysacc_synt PF01943.12 EGG00199.1 - 0.013 14.7 1.6 0.021 14.0 1.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein efThoc1 PF11957.3 EGG00202.1 - 1.8e-87 293.9 0.0 2.7e-45 154.7 0.0 2.6 2 1 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Myosin_head PF00063.16 EGG00203.1 - 5e-49 166.9 0.1 6e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.14 EGG00203.1 - 4e-08 32.7 3.8 1.2e-05 24.8 0.6 2.3 2 0 0 2 2 2 2 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 EGG00203.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGG00203.1 - 0.038 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EGG00203.1 - 0.09 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 EGG00203.1 - 0.14 11.8 0.2 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.1 EGG00203.1 - 0.16 11.5 1.2 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Glyco_transf_29 PF00777.13 EGG00204.1 - 0.0041 16.3 0.1 0.0061 15.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Hydrolase PF00702.21 EGG00206.1 - 1.2e-14 55.2 0.2 4.3e-07 30.5 0.0 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGG00206.1 - 5.8e-14 51.6 0.0 1.7e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EGG00206.1 - 6.2e-14 52.6 0.2 1.9e-12 47.7 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGG00206.1 - 5.3e-12 45.5 0.0 1.9e-11 43.7 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGG00206.1 - 0.0029 17.2 4.4 0.0067 16.0 0.1 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGG00206.1 - 0.007 16.6 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase APOC4 PF15119.1 EGG00207.1 - 0.034 14.1 0.2 0.071 13.0 0.2 1.5 1 0 0 1 1 1 0 Apolipoprotein C4 Trp_halogenase PF04820.9 EGG00207.1 - 0.061 11.9 0.6 0.087 11.4 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Tetraspannin PF00335.15 EGG00208.1 - 3.7e-05 23.1 8.2 8.2e-05 21.9 5.7 1.5 1 1 0 1 1 1 1 Tetraspanin family Na_Ca_ex PF01699.19 EGG00208.1 - 0.11 12.1 8.5 0.44 10.1 3.8 2.2 2 0 0 2 2 2 0 Sodium/calcium exchanger protein Tetraspannin PF00335.15 EGG00209.1 - 6e-05 22.4 7.7 0.0002 20.7 5.4 1.9 1 1 0 1 1 1 1 Tetraspanin family DUF3488 PF11992.3 EGG00209.1 - 0.25 9.9 10.6 0.38 9.3 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Na_Ca_ex PF01699.19 EGG00209.1 - 1.7 8.2 7.8 15 5.1 0.0 2.4 2 1 0 2 2 2 0 Sodium/calcium exchanger protein Med6 PF04934.9 EGG00211.1 - 1.6e-34 118.4 0.0 2.5e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component DnaJ PF00226.26 EGG00212.1 - 2.9e-13 49.3 0.3 8.9e-13 47.7 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EGG00212.1 - 1.8e-05 24.2 1.0 0.0054 16.3 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EGG00212.1 - 5.6e-05 22.7 0.7 1.1 9.3 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGG00212.1 - 0.00016 21.9 1.3 0.049 14.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGG00212.1 - 0.00082 18.8 0.2 6.1 6.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGG00212.1 - 0.027 14.2 0.8 10 6.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat NYD-SP28 PF14772.1 EGG00212.1 - 0.33 11.0 6.3 0.42 10.7 0.1 3.7 3 1 0 3 3 3 0 Sperm tail Alpha_kinase PF02816.13 EGG00215.1 - 1e-09 38.3 0.8 1.6e-09 37.6 0.6 1.3 1 1 0 1 1 1 1 Alpha-kinase family Mer2 PF09074.5 EGG00217.1 - 0.04 13.8 1.4 0.05 13.5 0.9 1.1 1 0 0 1 1 1 0 Mer2 IncA PF04156.9 EGG00217.1 - 0.85 9.1 5.0 1.4 8.5 3.5 1.4 1 0 0 1 1 1 0 IncA protein Lactamase_B_2 PF12706.2 EGG00218.1 - 5.7e-14 52.1 0.0 1.2e-13 51.0 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain OB_NTP_bind PF07717.11 EGG00219.1 - 3.9e-26 91.1 0.0 4.9e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold GSu_C4xC__C2xCH PF09698.5 EGG00221.1 - 0.72 10.0 3.7 10 6.3 0.2 3.4 3 0 0 3 3 3 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Shisa PF13908.1 EGG00222.1 - 0.0022 18.1 1.2 0.0022 18.1 0.9 4.0 2 1 3 5 5 5 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EGG00222.1 - 0.047 14.0 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 EGG00222.1 - 0.053 13.1 0.4 0.093 12.3 0.3 1.3 1 0 0 1 1 1 0 IncA protein DUF4097 PF13349.1 EGG00222.1 - 0.07 12.6 0.5 0.1 12.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) TMEM154 PF15102.1 EGG00222.1 - 0.071 12.8 3.5 0.39 10.4 2.4 2.2 1 1 0 1 1 1 0 TMEM154 protein family Herpes_gE PF02480.11 EGG00222.1 - 0.098 10.9 0.0 0.098 10.9 0.0 2.1 1 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E ODV-E18 PF10717.4 EGG00222.1 - 0.46 9.9 5.9 2.4 7.6 0.0 3.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 RIC3 PF15361.1 EGG00222.1 - 2.2 8.4 14.2 0.076 13.2 0.3 2.4 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4381 PF14316.1 EGG00223.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) M PF02370.11 EGG00223.1 - 0.49 10.9 2.6 1.3 9.6 1.8 1.7 1 0 0 1 1 1 0 M protein repeat ABC2_membrane_4 PF12730.2 EGG00224.1 - 0.037 13.1 11.2 0.043 12.9 7.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Melibiase PF02065.13 EGG00225.1 - 3.9e-10 38.9 0.1 5.8e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Melibiase ECH_C PF13766.1 EGG00228.1 - 5.7e-30 103.8 0.0 1.6e-29 102.4 0.0 1.7 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EGG00228.1 - 1.2e-28 99.9 0.0 2.4e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Xylo_C PF12529.3 EGG00228.1 - 0.07 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Xylosyltransferase C terminal Thi4 PF01946.12 EGG00230.1 - 8.3e-94 312.9 0.0 1e-93 312.6 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EGG00230.1 - 3.2e-07 29.5 0.1 4.7e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGG00230.1 - 1.3e-06 28.3 0.4 3.6e-06 26.9 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGG00230.1 - 3.6e-06 26.1 0.2 6.1e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EGG00230.1 - 2e-05 24.5 0.1 3.6e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGG00230.1 - 0.00015 20.7 0.3 0.00032 19.6 0.3 1.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EGG00230.1 - 0.00033 20.4 0.1 0.0012 18.6 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EGG00230.1 - 0.00082 17.9 0.2 0.0012 17.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EGG00230.1 - 0.0084 16.1 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGG00230.1 - 0.012 14.6 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGG00230.1 - 0.018 13.6 0.1 0.027 13.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 EGG00230.1 - 0.049 12.4 0.4 0.076 11.8 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EGG00230.1 - 0.11 11.5 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain V-set_CD47 PF08204.6 EGG00230.1 - 0.16 11.7 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain K_oxygenase PF13434.1 EGG00230.1 - 0.17 10.7 0.0 0.36 9.6 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pribosyltran_N PF13793.1 EGG00232.1 - 4.2e-40 136.0 0.2 2.4e-38 130.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGG00232.1 - 4.6e-38 130.8 5.0 3.5e-32 111.6 0.6 2.8 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGG00232.1 - 1.1e-13 50.9 3.2 2.3e-13 49.9 0.3 2.5 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGG00232.1 - 0.004 16.3 0.1 0.007 15.5 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase FMN_red PF03358.10 EGG00232.1 - 0.086 12.3 0.1 1.5 8.3 0.0 2.5 3 0 0 3 3 3 0 NADPH-dependent FMN reductase Peptidase_M48 PF01435.13 EGG00234.1 - 1.9e-14 53.8 0.2 2.3e-14 53.4 0.2 1.0 1 0 0 1 1 1 1 Peptidase family M48 BcrAD_BadFG PF01869.15 EGG00235.1 - 1.9e-13 50.3 0.1 9.7e-12 44.7 0.0 3.0 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Corona_RPol_N PF06478.8 EGG00237.1 - 0.014 14.1 0.0 0.034 12.8 0.0 1.6 2 0 0 2 2 2 0 Coronavirus RPol N-terminus MoaE PF02391.12 EGG00237.1 - 0.09 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 MoaE protein DUF2018 PF09442.5 EGG00238.1 - 0.14 12.7 0.2 0.26 11.8 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2018) MCM_bind PF09739.4 EGG00239.1 - 3e-20 72.0 0.0 5.7e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 EGG00239.1 - 4.9e-15 55.6 0.6 1.1e-14 54.4 0.4 1.7 1 0 0 1 1 1 1 Putative alanine racemase DNA_ligase_A_N PF04675.9 EGG00241.1 - 1.1e-11 44.8 1.0 1.4e-08 34.7 0.0 2.7 2 1 1 3 3 3 2 DNA ligase N terminus Myb_DNA-bind_3 PF12776.2 EGG00241.1 - 0.0024 18.4 0.3 0.0089 16.6 0.2 2.0 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Defensin_propep PF00879.13 EGG00241.1 - 0.18 11.7 0.1 0.18 11.7 0.1 3.0 4 0 0 4 4 4 0 Defensin propeptide PolyA_pol PF01743.15 EGG00242.1 - 1.2e-08 35.2 0.2 1.3e-08 35.0 0.1 1.1 1 0 0 1 1 1 1 Poly A polymerase head domain RNA_pol_Rpb2_7 PF04560.15 EGG00243.1 - 7e-08 32.6 0.1 8.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 AhpC-TSA_2 PF13911.1 EGG00244.1 - 4.2e-12 45.9 0.0 8.1e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGG00244.1 - 6.1e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family NDK PF00334.14 EGG00245.1 - 1.2e-54 183.7 0.0 1.4e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PRP4 PF08799.6 EGG00246.1 - 0.039 13.2 0.7 0.061 12.5 0.5 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like NAM-associated PF14303.1 EGG00247.1 - 0.00017 21.9 0.0 0.00028 21.2 0.0 1.4 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain KKLCAg1 PF15204.1 EGG00248.1 - 0.16 12.0 1.0 1.2 9.1 0.7 2.0 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 CARDB PF07705.6 EGG00249.1 - 0.072 13.1 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 CARDB Cyclin_N PF00134.18 EGG00250.1 - 4.6e-09 35.9 0.1 2.7e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF4630 PF15443.1 EGG00250.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) LrgB PF04172.11 EGG00252.1 - 3.2e-26 91.8 7.6 1.7e-25 89.4 2.9 2.6 2 0 0 2 2 2 2 LrgB-like family Transposase_28 PF04195.7 EGG00252.1 - 0.78 9.0 4.0 3 7.0 1.3 2.5 2 0 0 2 2 2 0 Putative gypsy type transposon Peptidase_M16 PF00675.15 EGG00253.1 - 3.2e-39 134.0 4.0 5.9e-39 133.2 0.0 3.3 3 1 1 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGG00253.1 - 4.2e-35 121.0 0.7 1.4e-20 73.7 0.0 4.1 4 0 0 4 4 4 2 Peptidase M16 inactive domain DUF1625 PF07787.7 EGG00254.1 - 0.036 13.3 0.6 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) zf-C2H2_2 PF12756.2 EGG00255.1 - 2.8e-26 91.5 10.9 2.1e-20 72.7 2.0 4.0 3 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EGG00255.1 - 3.8e-06 26.8 0.6 0.00081 19.4 0.2 4.4 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGG00255.1 - 0.0014 18.7 0.5 0.0014 18.7 0.3 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 EGG00255.1 - 0.0062 16.1 1.1 0.023 14.3 0.0 2.4 3 0 0 3 3 3 1 DBF zinc finger Cellulase PF00150.13 EGG00256.1 - 0.00055 19.2 0.2 0.0022 17.2 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EGG00256.1 - 0.047 14.1 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Sugar-binding cellulase-like SpoIIE PF07228.7 EGG00257.1 - 9.2e-08 32.0 0.0 2e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EGG00257.1 - 0.0005 19.5 0.0 0.19 11.1 0.2 2.4 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGG00257.1 - 0.0091 15.4 0.2 0.026 13.9 0.1 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C TruD PF01142.13 EGG00259.1 - 0.00044 19.0 0.0 0.00044 19.0 0.0 1.0 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Cu-oxidase_2 PF07731.9 EGG00260.1 - 3.3e-38 130.2 0.4 2.6e-30 104.7 0.0 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGG00260.1 - 1.2e-36 124.9 7.9 8.8e-36 122.2 0.8 3.6 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EGG00260.1 - 6.3e-22 78.1 3.8 1e-20 74.2 0.0 3.4 4 0 0 4 4 4 1 Multicopper oxidase DUF3439 PF11921.3 EGG00260.1 - 0.088 12.5 2.6 0.29 10.8 1.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF3952 PF13130.1 EGG00262.1 - 0.0096 15.8 0.7 0.023 14.6 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3952) Peptidase_M24 PF00557.19 EGG00263.1 - 2e-44 151.6 0.0 2.5e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EGG00263.1 - 0.00059 19.6 6.6 0.0017 18.1 4.6 1.8 1 0 0 1 1 1 1 MYND finger DUF329 PF03884.9 EGG00263.1 - 0.23 11.0 6.3 0.54 9.8 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF329) zf-HIT PF04438.11 EGG00263.1 - 3.9 7.2 10.1 0.94 9.1 4.5 1.9 2 0 0 2 2 2 0 HIT zinc finger DEAD PF00270.24 EGG00264.1 - 0.027 13.9 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase HDV_ag PF01517.13 EGG00264.1 - 0.49 10.0 7.2 0.81 9.3 5.0 1.3 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen HAD PF12710.2 EGG00267.1 - 2.5e-15 57.1 0.1 9.4e-15 55.2 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGG00267.1 - 2.1e-14 54.4 0.0 4.7e-12 46.7 0.0 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGG00267.1 - 1e-12 47.5 0.7 2.9e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EGG00267.1 - 7.7e-10 38.6 0.0 1.7e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGG00267.1 - 4.4e-07 29.7 0.1 0.00082 19.0 0.1 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGG00267.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase His_Phos_1 PF00300.17 EGG00269.1 - 3e-24 85.8 0.2 8.4e-24 84.4 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Fungal_trans PF04082.13 EGG00271.1 - 5.3e-15 54.9 0.5 1.2e-14 53.8 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGG00271.1 - 4.3e-08 32.9 7.1 4.3e-08 32.9 4.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_polI_A34 PF08208.6 EGG00272.1 - 2.6e-05 23.9 11.6 0.0021 17.7 0.2 2.2 2 0 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 Thiolase_N PF00108.18 EGG00276.1 - 4.9e-72 242.0 0.0 9.2e-72 241.1 0.0 1.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGG00276.1 - 1.9e-43 146.7 0.0 4e-43 145.7 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGG00276.1 - 0.11 12.0 0.6 0.25 10.8 0.4 1.6 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Septin PF00735.13 EGG00277.1 - 1e-112 375.8 1.5 1.2e-112 375.5 1.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EGG00277.1 - 8.6e-09 35.3 0.0 2.5e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGG00277.1 - 8.3e-07 28.3 0.1 1.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EGG00277.1 - 3.1e-06 26.7 0.8 1.8e-05 24.2 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGG00277.1 - 5.9e-06 25.5 0.0 1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGG00277.1 - 1.4e-05 25.0 0.5 0.027 14.2 0.1 2.4 1 1 1 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.13 EGG00277.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 EGG00277.1 - 0.00036 19.7 0.3 0.00066 18.8 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_10 PF12846.2 EGG00277.1 - 0.00048 19.6 0.2 0.00054 19.4 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 EGG00277.1 - 0.00066 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 EGG00277.1 - 0.00076 19.9 0.2 0.004 17.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 EGG00277.1 - 0.0012 17.7 0.1 0.0026 16.7 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.17 EGG00277.1 - 0.0028 16.5 0.1 0.0047 15.8 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_29 PF13555.1 EGG00277.1 - 0.021 14.3 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EGG00277.1 - 0.025 14.7 0.1 0.052 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGG00277.1 - 0.025 14.5 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain IIGP PF05049.8 EGG00277.1 - 0.034 12.9 0.0 0.068 11.9 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Ras PF00071.17 EGG00277.1 - 0.049 13.0 0.3 0.2 11.0 0.1 2.1 2 0 0 2 2 2 0 Ras family MobB PF03205.9 EGG00277.1 - 0.052 13.2 0.1 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EGG00277.1 - 0.082 12.7 0.1 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF87 RuvB_N PF05496.7 EGG00277.1 - 0.089 11.8 0.1 0.25 10.3 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGG00277.1 - 0.09 12.6 0.7 0.23 11.3 0.0 2.1 3 1 0 3 3 2 0 AAA domain AAA_24 PF13479.1 EGG00277.1 - 0.09 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CLASP_N PF12348.3 EGG00278.1 - 6.3e-24 84.5 10.0 3.1e-09 36.5 0.0 5.7 6 0 0 6 6 6 4 CLASP N terminal HEAT PF02985.17 EGG00278.1 - 7.6e-16 56.7 13.3 0.53 10.5 0.1 10.7 12 0 0 12 12 12 6 HEAT repeat HEAT_2 PF13646.1 EGG00278.1 - 1.5e-09 37.9 22.7 0.0012 19.1 0.1 9.8 8 2 3 11 11 11 1 HEAT repeats Proteasom_PSMB PF10508.4 EGG00278.1 - 2.6e-06 26.0 1.0 0.00052 18.4 0.0 3.7 4 0 0 4 4 4 1 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 EGG00278.1 - 0.0055 16.6 0.3 13 5.7 0.1 4.1 3 0 0 3 3 3 1 V-ATPase subunit H DUF2435 PF10363.4 EGG00278.1 - 0.0074 16.1 0.1 11 6.0 0.0 4.5 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EGG00278.1 - 0.0074 16.7 10.0 72 4.0 0.5 7.5 7 0 0 7 7 7 0 HEAT-like repeat Dopey_N PF04118.9 EGG00278.1 - 0.022 13.5 0.0 1.7 7.3 0.0 2.8 2 0 0 2 2 2 0 Dopey, N-terminal VHS PF00790.14 EGG00278.1 - 0.047 13.3 2.8 13 5.3 0.0 4.5 5 0 0 5 5 5 0 VHS domain Arm PF00514.18 EGG00278.1 - 0.48 10.3 3.4 29 4.6 0.1 5.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Rhodanese PF00581.15 EGG00281.1 - 3.6e-19 69.1 0.0 3.3e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain RINGv PF12906.2 EGG00282.1 - 0.064 13.3 0.2 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 RING-variant domain CwfJ_C_1 PF04677.10 EGG00284.1 - 3.6e-30 104.1 0.0 6.7e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EGG00284.1 - 4.5e-16 59.1 0.2 9.1e-16 58.1 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 EGG00284.1 - 1.1e-08 34.3 9.8 2.6e-05 23.6 1.7 2.6 1 1 1 2 2 2 2 Zinc knuckle eIF3g PF12353.3 EGG00284.1 - 0.00032 20.6 5.9 0.074 12.9 0.5 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.18 EGG00284.1 - 0.00051 19.8 11.0 0.04 13.8 0.5 3.3 3 0 0 3 3 3 2 Zinc knuckle CAP_GLY PF01302.20 EGG00284.1 - 0.012 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 CAP-Gly domain zf-CCHC_3 PF13917.1 EGG00284.1 - 0.04 13.6 5.5 0.075 12.7 0.5 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGG00284.1 - 0.1 12.3 3.2 4.3 7.0 0.2 3.1 3 0 0 3 3 3 0 Zinc knuckle Dus PF01207.12 EGG00285.1 - 4.9e-52 176.6 0.0 8.8e-52 175.8 0.0 1.3 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) zf-C2H2 PF00096.21 EGG00286.1 - 6e-11 42.0 13.2 6.9e-07 29.2 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG00286.1 - 3e-08 33.4 12.0 1.3e-05 25.2 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGG00286.1 - 0.0002 21.4 5.9 0.01 15.9 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EGG00286.1 - 0.0012 19.0 12.6 0.067 13.5 0.5 2.7 3 0 0 3 3 2 2 Zinc-finger double domain zf-met PF12874.2 EGG00286.1 - 0.0061 16.7 5.9 0.32 11.2 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EGG00286.1 - 0.0084 16.2 2.2 0.0084 16.2 1.5 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 EGG00286.1 - 0.029 14.0 3.4 0.029 14.0 2.3 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EGG00286.1 - 0.31 11.0 8.4 5.4 7.0 1.8 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Rad50_zn_hook PF04423.9 EGG00286.1 - 0.37 10.2 8.3 0.57 9.6 0.5 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif OrfB_Zn_ribbon PF07282.6 EGG00286.1 - 0.46 10.1 5.1 9.5 5.9 2.1 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain FYVE PF01363.16 EGG00286.1 - 1.3 8.9 10.2 0.42 10.5 4.9 1.8 2 0 0 2 2 2 0 FYVE zinc finger SF3a60_bindingd PF12108.3 EGG00287.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain OTU PF02338.14 EGG00290.1 - 2.2e-17 63.7 0.2 1.4e-16 61.1 0.0 2.2 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGG00290.1 - 0.0011 18.4 1.6 1.6 8.0 0.0 3.2 4 0 0 4 4 4 2 Peptidase C65 Otubain ApoO PF09769.4 EGG00290.1 - 9.8 5.8 8.6 0.87 9.2 0.5 3.0 3 0 0 3 3 3 0 Apolipoprotein O TF_Zn_Ribbon PF08271.7 EGG00291.1 - 0.044 13.1 0.1 0.086 12.1 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding THOC7 PF05615.8 EGG00292.1 - 0.00087 19.5 9.4 0.00087 19.5 6.5 2.4 2 1 0 2 2 2 1 Tho complex subunit 7 PAM2 PF07145.10 EGG00292.1 - 0.17 11.4 0.2 0.46 10.0 0.1 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region MFS_1 PF07690.11 EGG00293.1 - 5.9e-09 35.0 26.4 8.1e-08 31.3 18.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EGG00294.1 - 2.3e-22 79.2 28.4 3e-22 78.8 19.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1469 PF07332.6 EGG00294.1 - 3.1 7.5 8.9 0.89 9.2 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Vps51 PF08700.6 EGG00295.1 - 1.1e-13 50.7 1.7 1.5e-13 50.4 0.2 1.9 2 0 0 2 2 2 1 Vps51/Vps67 p450 PF00067.17 EGG00296.1 - 1.2e-43 149.2 0.0 2.1e-15 56.2 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 Smr PF01713.16 EGG00297.1 - 2.2e-08 34.1 0.0 6.3e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EGG00297.1 - 0.065 13.2 4.2 0.12 12.4 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) FAR1 PF03101.10 EGG00299.1 - 2.1e-07 31.3 1.4 2.8e-07 30.9 0.1 1.8 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.6 EGG00299.1 - 2.4e-05 24.5 0.4 2.4e-05 24.5 0.3 1.9 2 0 0 2 2 2 1 Transcription factor AFT Helicase_C_4 PF13871.1 EGG00299.1 - 0.0019 17.6 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 Helicase_C-like UBN2_2 PF14227.1 EGG00303.1 - 0.0016 17.9 0.7 0.0041 16.6 0.1 2.0 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type DUF249 PF03158.8 EGG00303.1 - 0.0085 15.6 0.2 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Multigene family 530 protein F-box-like PF12937.2 EGG00304.1 - 0.002 17.8 0.8 0.01 15.5 0.6 2.3 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EGG00304.1 - 0.15 11.8 0.1 0.15 11.8 0.1 2.9 3 0 0 3 3 3 0 Leucine rich repeat LETM1 PF07766.8 EGG00307.1 - 2.4e-100 335.0 5.9 2.4e-100 335.0 4.1 2.1 2 1 0 2 2 2 1 LETM1-like protein EF-hand_8 PF13833.1 EGG00307.1 - 4.2e-06 26.2 0.7 0.00019 20.9 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EGG00307.1 - 2.4e-05 24.3 1.4 0.022 14.9 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 EGG00307.1 - 0.012 14.8 3.4 0.9 8.9 0.0 3.9 4 0 0 4 4 4 0 EF hand DUF2963 PF11178.3 EGG00307.1 - 0.042 13.2 0.4 0.081 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) tRNA-synt_2b PF00587.20 EGG00310.1 - 5.1e-66 221.5 0.1 9e-66 220.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGG00310.1 - 1.2e-19 70.0 1.0 1.7e-19 69.5 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain Retinal PF15449.1 EGG00311.1 - 0.097 10.3 11.0 0.12 10.0 7.6 1.2 1 0 0 1 1 1 0 Retinal protein MBOAT_2 PF13813.1 EGG00312.1 - 1.2e-13 50.8 3.0 6.1e-13 48.6 2.1 2.2 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Bac_export_2 PF01312.14 EGG00312.1 - 0.13 11.1 1.1 0.21 10.4 0.8 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF1751 PF08551.5 EGG00316.1 - 1.2e-24 86.4 1.8 2.9e-24 85.2 1.2 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EGG00316.1 - 0.00026 21.0 11.2 0.00047 20.2 7.8 1.4 1 0 0 1 1 1 1 Rhomboid family Methyltransf_33 PF10017.4 EGG00318.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DUF1846 PF08903.6 EGG00318.1 - 0.15 10.5 0.0 0.15 10.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Zn_clus PF00172.13 EGG00319.1 - 0.00017 21.4 11.1 0.00041 20.1 7.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S9 PF00380.14 EGG00320.1 - 1.5e-38 131.7 0.2 1.8e-38 131.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ldh_1_C PF02866.13 EGG00321.1 - 1.6e-13 50.7 0.1 1.9e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Brix PF04427.13 EGG00322.1 - 0.0074 15.9 0.0 0.0079 15.8 0.0 1.0 1 0 0 1 1 1 1 Brix domain DUF365 PF04033.7 EGG00323.1 - 0.093 12.7 0.2 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF365) YABBY PF04690.8 EGG00324.1 - 5.8e-07 29.9 0.1 8.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 YABBY protein HMG_box_2 PF09011.5 EGG00324.1 - 0.069 13.5 0.4 0.12 12.7 0.2 1.4 1 1 0 1 1 1 0 HMG-box domain RRM_1 PF00076.17 EGG00325.1 - 5.6e-40 134.8 1.2 1.8e-17 62.7 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG00325.1 - 4.7e-31 106.5 0.1 1.9e-15 56.5 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG00325.1 - 1.5e-14 53.5 0.1 6.1e-06 25.9 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGG00325.1 - 0.0073 16.0 0.0 0.34 10.7 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EGG00325.1 - 0.072 12.9 0.0 1.3 8.9 0.0 2.4 2 1 0 2 2 2 0 RNA binding motif AMP-binding PF00501.23 EGG00329.1 - 3.8e-18 65.1 0.0 9.8e-11 40.6 0.0 3.1 2 1 1 3 3 3 3 AMP-binding enzyme PP-binding PF00550.20 EGG00329.1 - 0.00013 22.1 0.0 0.00041 20.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site HEAT PF02985.17 EGG00330.1 - 2.4e-40 132.9 25.3 0.003 17.5 0.0 12.6 13 0 0 13 13 13 11 HEAT repeat HEAT_2 PF13646.1 EGG00330.1 - 4.6e-31 106.9 12.3 8.4e-08 32.4 0.0 6.4 3 1 5 8 8 8 8 HEAT repeats HEAT_EZ PF13513.1 EGG00330.1 - 2.2e-14 53.4 12.0 0.0025 18.2 0.4 7.9 7 1 1 8 8 8 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGG00330.1 - 3.4e-13 49.7 0.3 0.048 14.0 0.0 7.2 2 1 6 8 8 8 3 Vacuolar 14 Fab1-binding region Arm PF00514.18 EGG00330.1 - 0.00022 20.9 0.2 0.74 9.7 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 EGG00330.1 - 0.0013 17.8 0.2 0.011 14.7 0.0 2.3 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.15 EGG00330.1 - 0.0022 16.3 3.1 0.11 10.7 2.2 3.2 1 1 1 2 2 2 2 Adaptin N terminal region RhoGEF PF00621.15 EGG00331.1 - 3.9e-13 49.6 0.1 7.2e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain Arch_ATPase PF01637.13 EGG00331.1 - 0.059 13.0 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Archaeal ATPase CPSase_L_D2 PF02786.12 EGG00332.1 - 5.1e-113 375.5 0.5 4.3e-82 274.5 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.16 EGG00332.1 - 3.2e-45 153.2 0.0 6.4e-45 152.3 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.23 EGG00332.1 - 2.8e-44 150.8 0.0 5.3e-44 149.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 EGG00332.1 - 8.7e-43 145.0 0.1 1.8e-42 143.9 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_sm_chain PF00988.17 EGG00332.1 - 6.9e-41 138.8 0.0 1.8e-40 137.4 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_chain PF00289.17 EGG00332.1 - 4.3e-38 129.8 0.0 1.3e-19 70.3 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 EGG00332.1 - 7.7e-38 129.8 0.0 1.7e-37 128.7 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EGG00332.1 - 2.3e-34 118.7 0.1 9.5e-23 80.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGG00332.1 - 4.1e-20 71.7 0.0 6.4e-12 44.8 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EGG00332.1 - 1.3e-18 66.6 0.0 1.6e-17 63.2 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.17 EGG00332.1 - 4e-15 55.5 0.1 7.3e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGG00332.1 - 4.2e-15 55.6 0.3 2e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.8 EGG00332.1 - 5.1e-07 29.3 0.1 5.5e-05 22.7 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EGG00332.1 - 3.6e-06 26.9 0.3 0.0076 16.1 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain EOS1 PF12326.3 EGG00335.1 - 0.0031 17.1 2.1 0.0031 17.1 1.5 1.3 1 1 0 1 1 1 1 N-glycosylation protein DUF989 PF06181.6 EGG00335.1 - 0.065 12.2 0.2 0.065 12.2 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF989) GPI-anchored PF10342.4 EGG00336.1 - 0.0073 16.7 0.9 0.0073 16.7 0.6 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GDI PF00996.13 EGG00337.1 - 7.4e-149 495.7 0.0 8.2e-149 495.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Minor_capsid_1 PF10665.4 EGG00338.1 - 0.076 12.8 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 Minor capsid protein DUF1971 PF09313.6 EGG00340.1 - 0.042 13.5 0.0 0.087 12.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1971) PDZ_2 PF13180.1 EGG00341.1 - 2.4e-06 27.3 0.0 5.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EGG00341.1 - 0.00013 22.0 0.0 0.00028 20.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 EGG00341.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.7 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain Prefoldin_2 PF01920.15 EGG00342.1 - 4.9e-15 55.2 10.5 5.8e-15 54.9 7.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit FliD_C PF07195.7 EGG00342.1 - 0.0026 17.0 4.8 0.0035 16.6 3.3 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus XRCC4 PF06632.7 EGG00342.1 - 0.0037 16.1 1.3 0.0037 16.1 0.9 1.5 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Snapin_Pallidin PF14712.1 EGG00342.1 - 0.011 15.9 9.3 0.13 12.5 0.9 2.2 1 1 1 2 2 2 0 Snapin/Pallidin FTA4 PF13093.1 EGG00342.1 - 0.035 13.5 10.4 0.038 13.4 5.5 1.8 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Spc7 PF08317.6 EGG00342.1 - 0.075 11.6 8.2 0.094 11.3 5.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 EGG00342.1 - 0.096 12.7 6.6 2.6 8.0 0.4 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIVA PF05103.8 EGG00342.1 - 0.12 12.4 7.4 0.24 11.4 5.1 1.5 1 1 0 1 1 1 0 DivIVA protein HrpB7 PF09486.5 EGG00342.1 - 0.17 11.8 1.9 1.3 8.8 0.2 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.10 EGG00342.1 - 0.2 11.6 7.1 0.25 11.3 4.9 1.1 1 0 0 1 1 1 0 Fez1 Prefoldin PF02996.12 EGG00342.1 - 0.22 11.1 8.4 0.19 11.4 1.0 2.2 1 1 2 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.3 EGG00342.1 - 0.26 11.1 8.8 0.85 9.4 1.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Med9 PF07544.8 EGG00342.1 - 0.35 10.6 3.7 1.7 8.4 0.1 2.5 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PEP-utilisers_N PF05524.8 EGG00342.1 - 0.44 10.3 5.9 3.5 7.4 0.1 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal OmpH PF03938.9 EGG00342.1 - 1 9.2 8.4 3 7.7 5.8 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.7 EGG00342.1 - 1.1 9.5 4.7 8.8 6.6 0.2 2.3 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF342 PF03961.8 EGG00342.1 - 1.3 7.3 7.7 6.8 4.9 5.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 EGG00342.1 - 1.4 9.3 7.3 0.66 10.3 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF848 PF05852.6 EGG00342.1 - 1.4 8.7 7.4 1.6 8.5 0.6 2.1 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DASH_Dad2 PF08654.5 EGG00342.1 - 1.9 8.5 8.4 1.5 8.8 0.5 2.3 1 1 1 2 2 2 0 DASH complex subunit Dad2 Occludin_ELL PF07303.8 EGG00342.1 - 2.1 9.1 6.6 8.2 7.2 0.3 2.2 1 1 0 2 2 2 0 Occludin homology domain TPD52 PF04201.10 EGG00342.1 - 3.2 7.4 8.9 0.24 11.1 0.9 2.0 2 0 0 2 2 2 0 Tumour protein D52 family DivIC PF04977.10 EGG00342.1 - 4.5 6.8 8.8 2.8 7.4 0.6 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF465 PF04325.8 EGG00342.1 - 4.7 6.9 8.3 3 7.6 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF465) CorA PF01544.13 EGG00342.1 - 5.6 5.9 7.4 6.3 5.7 5.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Bap31 PF05529.7 EGG00342.1 - 6.6 6.1 10.6 1.8 7.9 2.0 2.0 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DUF4337 PF14235.1 EGG00342.1 - 7 6.4 6.1 21 4.9 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) NUP50 PF08911.6 EGG00345.1 - 8.8e-09 35.6 0.5 8.8e-09 35.6 0.4 5.5 6 1 0 6 6 6 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.13 EGG00345.1 - 1e-08 35.2 2.3 1.1e-08 35.0 0.5 1.9 2 0 0 2 2 2 1 RanBP1 domain Nucleoporin_FG PF13634.1 EGG00345.1 - 1.2e-08 35.2 67.4 1e-05 25.6 19.6 6.2 2 2 2 4 4 4 2 Nucleoporin FG repeat region Rap_GAP PF02145.10 EGG00346.1 - 1.3e-44 151.8 0.0 2.1e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EGG00346.1 - 2.9e-11 43.0 3.5 7.7e-09 35.0 0.2 2.2 2 0 0 2 2 2 2 Tuberin Alpha_kinase PF02816.13 EGG00347.1 - 8.9e-13 48.3 0.1 1.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family Pkinase PF00069.20 EGG00348.1 - 1.7e-62 210.8 0.0 2e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG00348.1 - 4.9e-30 104.4 0.0 5.7e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGG00348.1 - 0.00045 19.3 0.0 0.00084 18.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGG00348.1 - 0.012 14.5 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_C PF00433.19 EGG00348.1 - 0.24 11.9 2.2 0.45 11.0 1.5 1.5 1 0 0 1 1 1 0 Protein kinase C terminal domain Ribosomal_L34e PF01199.13 EGG00349.1 - 7.9e-35 118.9 3.0 1.1e-34 118.5 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.1 EGG00349.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.6 1 1 0 1 1 1 0 Cytochrome c7 FhuF_C PF11575.3 EGG00349.1 - 0.22 11.1 3.1 3.6 7.3 0.5 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain KTI12 PF08433.5 EGG00350.1 - 4.7e-54 183.4 0.0 5e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EGG00350.1 - 7.1e-07 29.1 0.0 9.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG00350.1 - 0.00031 21.0 0.0 0.00046 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG00350.1 - 0.00047 20.9 0.0 0.00073 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EGG00350.1 - 0.042 12.8 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RBB1NT PF08169.6 EGG00350.1 - 0.059 13.3 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 RBB1NT (NUC162) domain DDOST_48kD PF03345.9 EGG00351.1 - 1e-117 393.2 0.0 1.1e-117 393.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Ric8 PF10165.4 EGG00352.1 - 8e-13 48.0 0.0 1.8e-12 46.8 0.0 1.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn Ric8 PF10165.4 EGG00353.1 - 3.9e-29 101.7 0.0 5.2e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn DUF1978 PF09321.5 EGG00353.1 - 0.092 12.1 5.9 0.15 11.4 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Tet_JBP PF12851.2 EGG00355.1 - 5.2e-06 25.8 0.0 8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Myosin_head PF00063.16 EGG00356.1 - 9.4e-21 73.5 0.0 1.1e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) DHC_N2 PF08393.8 EGG00357.1 - 5.3e-35 120.7 14.0 4.3e-17 61.7 0.6 4.3 3 2 1 4 4 4 3 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EGG00358.1 - 2.6e-40 138.3 0.2 1.2e-34 119.8 0.0 3.0 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 EGG00358.1 - 1.4e-11 43.5 0.1 2.6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.9 EGG00358.1 - 3.9e-08 33.1 0.0 2.4e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGG00358.1 - 0.031 14.1 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EGG00361.1 - 2.8e-13 49.7 0.0 6.8e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG00361.1 - 3.8e-07 29.8 0.0 7.6e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T4SS-DNA_transf PF02534.9 EGG00361.1 - 0.003 16.1 0.0 0.0048 15.5 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer DUF3505 PF12013.3 EGG00361.1 - 0.03 14.5 0.2 0.03 14.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) DUF1724 PF08350.5 EGG00361.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) HTH_32 PF13565.1 EGG00362.1 - 0.041 14.6 0.0 5.1 7.9 0.0 3.0 2 1 0 2 2 2 0 Homeodomain-like domain DUF883 PF05957.8 EGG00362.1 - 0.38 11.1 3.9 1.3 9.5 0.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) PI3_PI4_kinase PF00454.22 EGG00364.1 - 6.4e-27 94.5 0.0 7.2e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UcrQ PF02939.11 EGG00364.1 - 0.14 12.0 0.0 1.6 8.5 0.0 2.0 2 0 0 2 2 2 0 UcrQ family HTH_38 PF13936.1 EGG00365.1 - 0.0057 16.1 0.0 0.044 13.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain UBN2 PF14223.1 EGG00366.1 - 1.1e-05 25.1 0.5 2.5e-05 24.0 0.3 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG00366.1 - 2.7e-05 23.6 0.5 5.8e-05 22.6 0.3 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EGG00366.1 - 0.00033 20.2 1.7 0.0057 16.2 0.2 2.8 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type Pex24p PF06398.6 EGG00369.1 - 1.8e-31 109.2 2.4 2.4e-31 108.8 1.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rad10 PF03834.9 EGG00371.1 - 5.4e-26 90.0 0.0 1e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EGG00371.1 - 6.6e-07 29.3 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 EGG00371.1 - 0.0022 17.5 0.0 0.0054 16.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 EGG00371.1 - 0.01 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pkinase PF00069.20 EGG00372.1 - 4.5e-17 62.0 0.0 1.1e-07 31.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGG00372.1 - 1.2e-09 37.6 0.1 0.00086 18.4 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase PITH PF06201.8 EGG00373.1 - 2.1e-38 131.4 0.0 2.6e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain TPR_8 PF13181.1 EGG00374.1 - 1e-06 28.0 0.1 0.087 12.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGG00374.1 - 7.4e-06 26.1 0.8 0.00063 20.1 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGG00374.1 - 1e-05 25.0 2.4 0.0031 17.2 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGG00374.1 - 1.5e-05 24.5 0.3 0.00024 20.6 0.3 2.5 2 1 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 EGG00374.1 - 7.3e-05 23.3 0.1 0.0055 17.3 0.5 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGG00374.1 - 8.3e-05 22.1 1.3 0.007 16.0 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGG00374.1 - 0.0002 20.8 1.0 0.033 13.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGG00374.1 - 0.00021 21.5 0.1 0.00081 19.6 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGG00374.1 - 0.00032 20.6 0.0 0.45 10.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGG00374.1 - 0.0043 16.9 1.2 0.29 11.1 1.5 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGG00374.1 - 0.006 16.9 1.0 2 9.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGG00374.1 - 0.012 14.6 0.0 0.041 12.9 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EGG00374.1 - 0.02 15.0 3.0 0.21 11.7 1.2 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Adenylate_cycl PF01295.13 EGG00374.1 - 0.031 12.5 0.0 0.041 12.1 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I Peroxin-13_N PF04088.8 EGG00375.1 - 4.5e-38 130.6 0.3 8.8e-38 129.7 0.2 1.5 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 EGG00375.1 - 4e-10 38.9 0.1 7.2e-10 38.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGG00375.1 - 4.9e-10 38.7 0.2 9.2e-10 37.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EGG00375.1 - 1.6e-09 37.2 0.1 3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.9 EGG00375.1 - 0.003 17.0 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region SurE PF01975.12 EGG00376.1 - 5e-36 123.8 0.0 7.1e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Ion_trans PF00520.26 EGG00377.1 - 3.1e-07 29.8 2.7 3.1e-07 29.8 1.9 1.8 2 0 0 2 2 2 1 Ion transport protein GDI PF00996.13 EGG00379.1 - 4.2e-203 674.5 0.0 4.7e-203 674.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Glyco_hydro_18 PF00704.23 EGG00380.1 - 4.8e-63 213.6 0.0 5.4e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 EGG00380.1 - 0.00099 18.3 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 SMC_N PF02463.14 EGG00381.1 - 1.9e-26 92.6 0.0 5.9e-26 91.0 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGG00381.1 - 1.7e-05 25.2 35.0 1.7e-05 25.2 24.3 4.6 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EGG00381.1 - 2.2e-05 24.5 3.9 0.015 15.3 1.3 3.3 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EGG00381.1 - 0.0016 17.9 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ADIP PF11559.3 EGG00381.1 - 0.014 15.3 2.3 0.014 15.3 1.6 6.9 5 1 1 6 6 6 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EGG00381.1 - 0.18 11.6 0.1 0.18 11.6 0.0 7.1 5 3 2 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Dam1 PF08653.5 EGG00381.1 - 0.53 10.0 2.5 7.8 6.3 0.2 3.5 2 1 0 2 2 2 0 DASH complex subunit Dam1 AAA_13 PF13166.1 EGG00381.1 - 5.8 5.2 76.6 0.12 10.7 16.3 5.3 2 2 2 5 5 5 0 AAA domain SMC_N PF02463.14 EGG00382.1 - 9.3e-26 90.4 0.0 2.6e-25 88.9 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGG00382.1 - 5.8e-08 33.3 31.0 5.8e-08 33.3 21.5 4.3 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EGG00382.1 - 1.7e-05 24.9 3.1 0.057 13.3 1.9 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGG00382.1 - 6.5e-05 22.3 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ERM PF00769.14 EGG00382.1 - 0.0017 17.9 11.5 0.0017 17.9 7.9 4.2 2 2 2 4 4 4 1 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 EGG00382.1 - 9.7 5.2 23.6 4.7 6.3 2.7 4.4 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Tfb4 PF03850.9 EGG00383.1 - 0.024 13.8 0.2 0.031 13.5 0.2 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 zf-GRF PF06839.7 EGG00385.1 - 0.0081 16.0 2.4 0.013 15.4 1.7 1.3 1 0 0 1 1 1 1 GRF zinc finger REV PF00424.13 EGG00385.1 - 0.14 12.1 0.9 6.6 6.6 0.1 2.8 3 1 0 3 3 3 0 REV protein (anti-repression trans-activator protein) DUF2360 PF10152.4 EGG00385.1 - 0.38 11.0 6.7 0.5 10.6 4.7 1.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) zinc_ribbon_4 PF13717.1 EGG00385.1 - 4.6 7.0 9.5 7.4 6.3 1.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGG00385.1 - 5.6 6.6 9.3 9.7 5.8 1.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain APG12 PF04110.8 EGG00387.1 - 5.6e-34 116.1 0.0 7.1e-34 115.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EGG00387.1 - 3.7e-05 23.6 0.0 4.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Rad60-SLD PF11976.3 EGG00387.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L3 PF00297.17 EGG00388.1 - 1.8e-38 132.4 3.9 1.3e-36 126.3 2.7 2.2 1 1 0 1 1 1 1 Ribosomal protein L3 HrcA_DNA-bdg PF03444.10 EGG00388.1 - 0.035 13.5 0.1 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DUF2404 PF10296.4 EGG00389.1 - 2.3e-10 40.4 0.0 4.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ThiF PF00899.16 EGG00390.1 - 2.8e-31 108.1 0.0 5.6e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EGG00390.1 - 0.0023 18.0 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Ribosomal_L4 PF00573.17 EGG00391.1 - 2.6e-46 157.4 0.0 9.2e-46 155.6 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family DUF2484 PF10658.4 EGG00392.1 - 0.049 13.7 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) ESSS PF10183.4 EGG00393.1 - 0.29 11.5 1.6 11 6.4 1.1 2.1 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ORC6 PF05460.8 EGG00393.1 - 0.64 9.0 9.9 0.65 9.0 6.8 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Cwf_Cwc_15 PF04889.7 EGG00397.1 - 0.62 9.7 22.8 0.029 14.0 5.5 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Na_trans_assoc PF06512.8 EGG00397.1 - 8.3 6.2 17.7 3.9 7.3 4.2 2.1 2 0 0 2 2 2 0 Sodium ion transport-associated PfkB PF00294.19 EGG00398.1 - 1.5e-41 142.4 0.0 1.8e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Nitro_FeMo-Co PF02579.12 EGG00398.1 - 0.019 15.0 0.2 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Peptidase_M76 PF09768.4 EGG00399.1 - 1.1e-48 164.9 0.1 2.2e-48 164.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EGG00399.1 - 0.0052 16.4 0.3 0.011 15.4 0.2 1.9 1 1 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 EGG00399.1 - 0.043 13.8 0.6 0.067 13.2 0.4 1.5 1 1 0 1 1 1 0 Peptidase MA superfamily KH_1 PF00013.24 EGG00400.1 - 1.4e-41 139.9 9.5 1e-15 57.1 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGG00400.1 - 1.9e-31 107.1 12.9 6.8e-11 41.5 0.7 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EGG00400.1 - 4.9e-15 54.8 8.9 2.1e-05 24.0 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGG00400.1 - 3.6e-07 29.7 1.9 0.35 10.5 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EGG00400.1 - 0.023 14.4 4.4 9 6.1 0.1 3.4 3 0 0 3 3 3 0 NusA-like KH domain Pirin_C PF05726.8 EGG00400.1 - 0.075 13.1 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 Pirin C-terminal cupin domain PPP1R35_C PF15503.1 EGG00402.1 - 3.5 7.1 9.5 0.17 11.4 0.1 2.9 3 0 0 3 3 3 0 Protein phosphatase 1 regulatory subunit 35 C-terminus NAD_binding_6 PF08030.7 EGG00404.1 - 3.7e-16 59.4 0.0 2.7e-10 40.3 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EGG00404.1 - 2.1e-09 37.5 10.5 3.5e-08 33.5 7.2 2.5 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGG00404.1 - 5.6e-09 35.8 0.0 1.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EGG00404.1 - 0.054 14.0 0.0 0.8 10.2 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Zn_clus PF00172.13 EGG00405.1 - 2e-05 24.4 3.3 2.7e-05 23.9 2.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.4 EGG00405.1 - 0.1 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein KIF1B PF12423.3 EGG00405.1 - 0.16 11.9 0.4 0.44 10.6 0.3 1.7 1 0 0 1 1 1 0 Kinesin protein 1B TPR_9 PF13371.1 EGG00407.1 - 0.068 13.0 0.2 3.4 7.6 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2605 PF10792.4 EGG00407.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) KxDL PF10241.4 EGG00409.1 - 0.11 12.4 2.8 0.21 11.4 1.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF4355 PF14265.1 EGG00409.1 - 2.3 8.2 12.6 5.1 7.0 8.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) zf-C2H2 PF00096.21 EGG00410.1 - 2e-09 37.2 7.1 0.00014 21.9 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG00410.1 - 2.5e-07 30.6 2.9 0.00065 19.8 0.2 3.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGG00410.1 - 2.6e-06 27.3 4.9 0.00062 19.9 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGG00410.1 - 0.034 14.2 0.1 6.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding cEGF PF12662.2 EGG00410.1 - 0.12 12.0 0.4 0.36 10.5 0.3 1.8 1 0 0 1 1 1 0 Complement Clr-like EGF-like zf-H2C2_5 PF13909.1 EGG00410.1 - 0.18 12.1 3.6 1.5 9.2 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met PF12874.2 EGG00410.1 - 0.3 11.3 4.7 6.4 7.1 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EGG00410.1 - 0.32 10.7 2.9 1.6 8.5 0.0 2.9 3 0 0 3 3 3 0 BED zinc finger DUF1777 PF08648.7 EGG00411.1 - 8.1e-23 81.0 0.5 8.4e-23 81.0 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) TAT_ubiq PF07706.7 EGG00411.1 - 0.066 13.1 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Aminotransferase ubiquitination site Nuc_sug_transp PF04142.10 EGG00418.1 - 5.2e-79 264.7 5.2 9e-79 264.0 3.6 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EGG00418.1 - 8.9e-11 41.2 12.4 1.4e-10 40.5 8.6 1.3 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EGG00418.1 - 1.6e-08 34.7 1.1 1.6e-08 34.7 0.8 2.6 2 0 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EGG00418.1 - 3.8e-06 26.9 0.8 3.8e-06 26.9 0.6 3.0 3 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.11 EGG00418.1 - 0.00073 19.2 4.6 0.00073 19.2 3.2 2.9 2 2 0 2 2 2 1 Triose-phosphate Transporter family DUF3460 PF11943.3 EGG00420.1 - 0.012 15.6 0.1 0.04 13.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) Synaptobrevin PF00957.16 EGG00420.1 - 0.062 12.9 0.4 0.22 11.1 0.3 2.0 1 0 0 1 1 1 0 Synaptobrevin Zn_Tnp_IS1595 PF12760.2 EGG00421.1 - 0.68 9.7 5.7 1.1 9.1 2.0 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2296 PF10058.4 EGG00422.1 - 0.029 14.1 1.2 0.063 13.0 0.3 2.0 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DUF4462 PF14692.1 EGG00422.1 - 0.49 9.6 2.1 0.52 9.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4462) Desulfoferrod_N PF06397.7 EGG00424.1 - 0.076 12.4 3.7 0.24 10.8 0.1 2.5 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain EAF PF09816.4 EGG00425.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription elongation factor Polysacc_deac_1 PF01522.16 EGG00426.1 - 7.1e-20 70.8 0.0 1.2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Synaptobrevin PF00957.16 EGG00426.1 - 0.043 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Synaptobrevin Nuc_sug_transp PF04142.10 EGG00427.1 - 1.1e-74 250.6 9.8 1.1e-74 250.6 6.8 1.5 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 EGG00427.1 - 1.2e-09 38.3 15.2 4e-08 33.4 2.1 2.7 2 0 0 2 2 2 2 Multidrug resistance efflux transporter UAA PF08449.6 EGG00427.1 - 3.3e-08 32.8 13.5 8.6e-08 31.4 9.3 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGG00427.1 - 9.4e-06 25.6 4.9 9.4e-06 25.6 3.4 2.9 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.11 EGG00427.1 - 0.00014 21.5 17.8 0.00094 18.8 1.2 3.1 2 1 0 2 2 2 2 Triose-phosphate Transporter family An_peroxidase PF03098.10 EGG00429.1 - 0.085 11.2 0.0 0.085 11.2 0.0 1.2 1 0 0 1 1 1 0 Animal haem peroxidase Xpo1 PF08389.7 EGG00430.1 - 3.2e-18 66.0 0.0 1.4e-17 64.0 0.0 2.1 1 0 0 1 1 1 1 Exportin 1-like protein cobW PF02492.14 EGG00431.1 - 6.4e-45 152.7 8.3 4.8e-34 117.3 0.6 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EGG00431.1 - 6.8e-17 60.9 0.0 9.7e-13 47.6 0.0 2.4 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain Arch_ATPase PF01637.13 EGG00431.1 - 0.0035 17.0 0.5 0.014 15.1 0.0 2.3 3 0 0 3 3 3 1 Archaeal ATPase ATP_bind_1 PF03029.12 EGG00431.1 - 0.02 14.4 0.3 6.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Spt5_N PF11942.3 EGG00431.1 - 0.021 15.4 4.5 0.021 15.4 3.1 2.9 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal AAA_33 PF13671.1 EGG00431.1 - 0.029 14.2 0.1 0.24 11.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EGG00431.1 - 0.058 12.8 0.1 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain GTP_EFTU PF00009.22 EGG00431.1 - 0.062 12.7 4.2 4.4 6.7 1.2 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGG00431.1 - 0.08 13.0 0.1 0.35 11.0 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 EGG00431.1 - 0.086 12.3 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EGG00431.1 - 0.13 12.2 0.3 0.88 9.5 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EGG00431.1 - 5.5 7.3 7.0 0.49 10.7 0.4 2.6 2 1 1 3 3 3 0 AAA domain RRM_6 PF14259.1 EGG00435.1 - 0.02 14.8 0.0 0.055 13.4 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG00435.1 - 0.092 12.6 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CPSase_L_D2 PF02786.12 EGG00437.1 - 7.9e-34 116.7 0.2 1.2e-33 116.2 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain HMGL-like PF00682.14 EGG00437.1 - 1e-07 31.8 1.7 2.3e-07 30.7 1.2 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.14 EGG00437.1 - 0.00035 20.5 0.0 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Actin PF00022.14 EGG00446.1 - 0.049 12.0 0.1 0.071 11.5 0.1 1.2 1 0 0 1 1 1 0 Actin Citrate_synt PF00285.16 EGG00447.1 - 2.9e-95 319.0 0.0 3.5e-95 318.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase PSCyt2 PF07583.6 EGG00447.1 - 0.098 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Glyco_transf_43 PF03360.11 EGG00449.1 - 0.00037 20.1 0.0 0.00053 19.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 43 Mito_fiss_reg PF05308.6 EGG00451.1 - 0.0021 17.4 0.2 0.0024 17.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial fission regulator PEP-utilisers_N PF05524.8 EGG00451.1 - 0.092 12.5 0.1 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal PCI_Csn8 PF10075.4 EGG00452.1 - 0.0088 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Glyco_trans_1_2 PF13524.1 EGG00454.1 - 9.6e-05 22.5 0.0 0.00034 20.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_43 PF03360.11 EGG00457.1 - 3.9e-10 39.6 0.0 4.8e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 Sulfate_transp PF00916.15 EGG00460.1 - 3e-72 242.9 9.5 5.1e-72 242.2 6.6 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGG00460.1 - 7.6e-31 105.6 1.5 7.6e-31 105.6 1.0 3.6 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif 2OG-FeII_Oxy PF03171.15 EGG00461.1 - 3.4e-10 40.0 0.0 6.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGG00461.1 - 0.00035 21.0 0.0 0.00053 20.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal HMGL-like PF00682.14 EGG00462.1 - 1.3e-71 240.9 0.5 2.1e-71 240.3 0.1 1.5 2 0 0 2 2 2 1 HMGL-like ADP_PFK_GK PF04587.10 EGG00462.1 - 0.021 13.0 0.0 0.032 12.4 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region eRF1_2 PF03464.10 EGG00463.1 - 7.9e-45 152.4 0.1 1.6e-44 151.4 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EGG00463.1 - 7.2e-36 122.8 0.0 1.5e-35 121.8 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EGG00463.1 - 1.1e-26 92.9 0.0 2.5e-26 91.8 0.0 1.5 2 0 0 2 2 2 1 eRF1 domain 1 SPT16 PF08644.6 EGG00464.1 - 0.053 13.3 0.6 0.12 12.2 0.4 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Fibrinogen_aC PF12160.3 EGG00465.1 - 0.073 12.5 2.7 0.13 11.6 1.9 1.6 1 1 0 1 1 1 0 Fibrinogen alpha C domain Hid1 PF12722.2 EGG00465.1 - 0.082 10.5 6.2 0.094 10.3 4.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleo_P87 PF07267.6 EGG00465.1 - 0.23 10.1 7.3 0.29 9.7 5.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Daxx PF03344.10 EGG00465.1 - 0.24 9.8 14.4 0.3 9.5 10.0 1.1 1 0 0 1 1 1 0 Daxx Family Corona_nucleoca PF00937.13 EGG00465.1 - 0.26 10.1 11.8 0.33 9.8 8.2 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RNA_pol_3_Rpc31 PF11705.3 EGG00465.1 - 0.36 10.7 9.5 0.52 10.1 6.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.7 EGG00465.1 - 0.44 10.2 13.0 0.69 9.5 9.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Presenilin PF01080.12 EGG00465.1 - 1.4 7.7 4.5 1.6 7.4 3.1 1.1 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.1 EGG00465.1 - 1.4 8.2 7.8 1.8 7.9 5.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO PGA2 PF07543.7 EGG00465.1 - 2.8 7.7 11.7 0.71 9.6 5.7 1.6 1 1 1 2 2 2 0 Protein trafficking PGA2 CENP-B_dimeris PF09026.5 EGG00465.1 - 3.1 8.0 8.5 6 7.1 5.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PSK PF06404.7 EGG00465.1 - 3.3 8.5 8.2 1.3 9.8 3.4 1.9 1 1 1 2 2 2 0 Phytosulfokine precursor protein (PSK) Secretin_N_2 PF07655.8 EGG00465.1 - 4.3 7.7 14.0 0.35 11.2 6.2 1.7 2 0 0 2 2 2 0 Secretin N-terminal domain RXT2_N PF08595.6 EGG00465.1 - 5.9 6.6 7.9 9.8 5.9 5.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal MutS_V PF00488.16 EGG00467.1 - 9.5e-96 319.7 0.1 1.6e-95 319.0 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGG00467.1 - 4e-34 118.1 0.5 4e-34 118.1 0.3 2.2 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EGG00467.1 - 8.6e-19 67.5 1.6 8.6e-19 67.5 1.1 2.8 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.12 EGG00467.1 - 5.5e-15 55.6 0.2 1e-12 48.2 0.0 3.6 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.15 EGG00467.1 - 4.4e-12 46.0 0.0 1.3e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 MutS domain I PPR_2 PF13041.1 EGG00468.1 - 0.015 15.2 0.2 0.19 11.7 0.0 2.5 2 0 0 2 2 2 0 PPR repeat family PPR_3 PF13812.1 EGG00468.1 - 0.017 15.3 0.0 0.057 13.7 0.0 1.9 1 0 0 1 1 1 0 Pentatricopeptide repeat domain RRM_DME PF15628.1 EGG00468.1 - 0.066 12.9 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 RRM in Demeter PPR PF01535.15 EGG00468.1 - 0.079 12.9 1.8 0.44 10.6 0.0 2.8 3 0 0 3 3 3 0 PPR repeat AAA PF00004.24 EGG00469.1 - 7.5e-45 152.3 0.1 4.3e-44 149.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGG00469.1 - 2.6e-08 33.6 0.1 7.6e-08 32.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGG00469.1 - 2e-07 31.0 0.0 5e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EGG00469.1 - 6.5e-07 28.5 0.2 5.8e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EGG00469.1 - 9.7e-07 28.9 0.6 0.00033 20.7 0.3 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGG00469.1 - 1.2e-06 28.5 0.7 5.4e-06 26.5 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_14 PF13173.1 EGG00469.1 - 5.4e-05 23.1 0.1 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EGG00469.1 - 0.00015 21.5 0.0 0.0028 17.4 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_28 PF13521.1 EGG00469.1 - 0.00049 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGG00469.1 - 0.00088 18.3 0.0 0.002 17.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 EGG00469.1 - 0.0013 18.4 2.8 0.075 12.7 0.0 3.1 2 1 0 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 EGG00469.1 - 0.0014 18.2 0.2 0.0036 17.0 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EGG00469.1 - 0.0018 19.0 0.0 0.0083 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EGG00469.1 - 0.0029 17.9 2.9 0.75 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGG00469.1 - 0.003 17.7 0.0 0.0081 16.3 0.0 1.7 2 0 0 2 2 1 1 RNA helicase NACHT PF05729.7 EGG00469.1 - 0.0032 17.1 0.1 0.055 13.1 0.0 2.3 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 EGG00469.1 - 0.0035 16.9 0.0 0.033 13.8 0.0 2.2 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EGG00469.1 - 0.004 16.7 0.0 0.026 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EGG00469.1 - 0.0041 15.8 0.0 0.0076 15.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EGG00469.1 - 0.0048 16.3 1.1 0.075 12.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EGG00469.1 - 0.0048 16.5 0.1 0.013 15.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGG00469.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGG00469.1 - 0.0064 15.6 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EGG00469.1 - 0.0077 15.4 0.1 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EGG00469.1 - 0.009 15.4 0.4 0.029 13.7 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 EGG00469.1 - 0.012 15.9 0.4 0.08 13.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGG00469.1 - 0.013 15.0 0.2 0.029 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGG00469.1 - 0.015 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 EGG00469.1 - 0.047 13.3 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AFG1_ATPase PF03969.11 EGG00469.1 - 0.05 12.4 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase cobW PF02492.14 EGG00469.1 - 0.07 12.5 0.0 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.21 EGG00469.1 - 0.11 11.9 0.1 1.4 8.3 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 EGG00469.1 - 0.12 11.4 1.3 0.49 9.4 0.0 2.4 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 EGG00469.1 - 0.14 12.2 0.6 0.57 10.2 0.0 2.3 2 1 0 2 2 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EGG00469.1 - 0.16 10.8 0.8 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.12 EGG00469.1 - 0.18 10.6 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 EGG00470.1 - 1.4e-49 167.8 0.0 4e-27 95.1 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGG00470.1 - 5.7e-19 69.1 0.4 0.0016 18.4 0.0 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EGG00470.1 - 5e-15 55.3 0.1 1.8e-06 27.3 0.0 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EGG00470.1 - 4.3e-08 32.6 0.5 9.1e-08 31.6 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 EGG00470.1 - 3.2e-07 31.2 0.0 0.051 14.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EGG00470.1 - 3.2e-07 30.8 0.0 0.025 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EGG00470.1 - 4e-07 30.1 0.0 0.0019 18.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EGG00470.1 - 6.4e-07 29.8 0.1 0.019 15.4 0.0 3.0 2 1 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EGG00470.1 - 1.4e-06 27.7 0.1 0.074 12.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 EGG00470.1 - 2.5e-06 26.8 0.0 0.34 9.8 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EGG00470.1 - 6.3e-06 26.3 0.1 0.014 15.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 EGG00470.1 - 1.3e-05 25.0 0.0 0.019 14.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGG00470.1 - 3.3e-05 23.1 0.0 0.038 13.1 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGG00470.1 - 7e-05 22.7 0.0 0.048 13.4 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.1 EGG00470.1 - 7.4e-05 23.0 0.1 0.4 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EGG00470.1 - 8.6e-05 21.4 0.2 0.11 11.2 0.1 2.4 2 0 0 2 2 2 2 ArgK protein RNA_helicase PF00910.17 EGG00470.1 - 9.7e-05 22.5 0.1 0.77 9.9 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_10 PF12846.2 EGG00470.1 - 0.00018 21.0 0.1 1 8.7 0.1 3.0 3 0 0 3 3 3 2 AAA-like domain NACHT PF05729.7 EGG00470.1 - 0.0003 20.5 0.4 0.075 12.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 EGG00470.1 - 0.00032 20.5 0.4 1.2 9.0 0.0 3.4 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EGG00470.1 - 0.00034 20.4 2.5 0.35 10.8 0.0 3.4 3 1 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EGG00470.1 - 0.00048 20.0 0.0 0.2 11.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EGG00470.1 - 0.00063 19.4 0.0 0.21 11.2 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B HEAT PF02985.17 EGG00470.1 - 0.00074 19.3 0.2 0.72 10.0 0.1 3.7 2 0 0 2 2 2 1 HEAT repeat AAA_16 PF13191.1 EGG00470.1 - 0.0033 17.4 0.0 4.5 7.2 0.0 3.0 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EGG00470.1 - 0.0036 17.5 0.0 6.3 7.0 0.0 3.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HEAT_2 PF13646.1 EGG00470.1 - 0.0069 16.6 3.9 1.1 9.5 0.0 4.2 1 1 3 4 4 4 2 HEAT repeats Arch_ATPase PF01637.13 EGG00470.1 - 0.0096 15.6 0.1 1.5 8.4 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase NB-ARC PF00931.17 EGG00470.1 - 0.011 14.6 0.1 0.76 8.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 EGG00470.1 - 0.017 14.5 0.0 9.3 5.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.10 EGG00470.1 - 0.017 13.7 0.0 2.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein PduV-EutP PF10662.4 EGG00470.1 - 0.021 14.3 0.0 6.7 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.1 EGG00470.1 - 0.03 12.7 0.1 3.9 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EGG00470.1 - 0.031 13.7 0.0 0.55 9.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EGG00470.1 - 0.038 12.9 0.1 8.9 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.12 EGG00470.1 - 0.042 13.6 1.0 1.1 9.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 KAP_NTPase PF07693.9 EGG00470.1 - 0.05 12.5 0.1 3.4 6.5 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Septin PF00735.13 EGG00470.1 - 0.058 12.3 0.0 6 5.7 0.0 2.3 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.7 EGG00470.1 - 0.064 12.3 1.4 3.2 6.7 0.1 3.1 3 0 0 3 3 3 0 Zeta toxin G-alpha PF00503.15 EGG00470.1 - 0.077 11.6 0.0 1.3 7.5 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATP-synt_ab PF00006.20 EGG00470.1 - 0.08 12.4 0.0 1.7 8.0 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 EGG00470.1 - 0.11 11.9 0.0 8.4 5.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 EGG00470.1 - 0.12 11.8 0.0 10 5.5 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HEAT_EZ PF13513.1 EGG00470.1 - 1 9.9 12.7 8.4 7.0 0.1 5.8 6 1 2 8 8 5 0 HEAT-like repeat F-box-like PF12937.2 EGG00471.1 - 0.042 13.5 0.0 0.2 11.4 0.0 2.2 1 0 0 1 1 1 0 F-box-like Dysbindin PF04440.11 EGG00471.1 - 0.078 12.7 4.6 0.15 11.8 3.2 1.4 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) DUF3680 PF12441.3 EGG00471.1 - 0.34 10.7 2.1 1.2 9.0 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3680) CRAL_TRIO PF00650.15 EGG00474.1 - 4.1e-12 45.8 0.0 6.4e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Med7 PF05983.6 EGG00474.1 - 0.099 12.4 0.1 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 MED7 protein IncA PF04156.9 EGG00475.1 - 0.0037 16.8 10.1 0.0037 16.8 7.0 1.6 2 0 0 2 2 2 1 IncA protein DUF572 PF04502.8 EGG00475.1 - 0.063 12.4 9.5 0.11 11.7 6.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF972 PF06156.8 EGG00475.1 - 0.09 13.1 8.6 0.28 11.5 5.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 EGG00475.1 - 0.14 11.2 0.7 0.23 10.6 0.5 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 EGG00475.1 - 0.25 10.3 13.9 0.5 9.3 9.6 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4407 PF14362.1 EGG00475.1 - 0.58 9.0 18.5 1 8.2 12.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.3 EGG00475.1 - 1.2 8.9 14.7 27 4.5 0.0 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PspB PF06667.7 EGG00475.1 - 1.5 8.7 5.1 2.3 8.2 0.8 2.4 2 0 0 2 2 2 0 Phage shock protein B V_ATPase_I PF01496.14 EGG00475.1 - 5.1 4.8 6.7 6.9 4.3 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GATA PF00320.22 EGG00476.1 - 8.8e-16 56.9 7.2 1.6e-15 56.1 5.0 1.5 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.13 EGG00476.1 - 0.0038 17.0 0.6 0.005 16.6 0.4 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DZR PF12773.2 EGG00476.1 - 0.013 15.2 3.2 0.053 13.3 2.2 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_3 PF13878.1 EGG00476.1 - 0.023 14.2 1.1 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-NADH-PPase PF09297.6 EGG00476.1 - 0.043 13.3 2.3 0.64 9.5 0.3 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 EGG00476.1 - 0.052 13.2 1.3 0.085 12.5 0.9 1.4 1 0 0 1 1 1 0 Nudix N-terminal zf-ribbon_3 PF13248.1 EGG00476.1 - 0.42 9.8 4.0 3 7.1 2.8 2.1 1 1 1 2 2 2 0 zinc-ribbon domain GSu_C4xC__C2xCH PF09698.5 EGG00476.1 - 0.51 10.5 4.9 2.1 8.5 3.4 2.0 1 1 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) RRN7 PF11781.3 EGG00476.1 - 2.7 7.5 5.4 18 4.9 3.8 2.1 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Spore_coat_CotO PF14153.1 EGG00477.1 - 0.2 11.0 4.7 0.33 10.3 0.4 2.4 2 1 0 2 2 2 0 Spore coat protein CotO Abhydrolase_6 PF12697.2 EGG00477.1 - 0.25 11.1 2.6 0.44 10.3 1.8 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family CbiG_C PF01890.11 EGG00477.1 - 7.3 6.8 12.2 0.32 11.2 0.5 2.9 2 1 0 2 2 2 0 Cobalamin synthesis G C-terminus SHR3_chaperone PF08229.6 EGG00478.1 - 9.7e-14 50.7 7.9 3.6e-13 48.9 5.5 1.9 1 1 0 1 1 1 1 ER membrane protein SH3 DUF3651 PF12371.3 EGG00478.1 - 0.23 11.4 7.2 1.5 8.8 3.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3651) IKI3 PF04762.7 EGG00479.1 - 8.9e-233 775.0 0.0 1.2e-232 774.5 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Apc4_WD40 PF12894.2 EGG00479.1 - 0.019 14.4 0.1 30 4.2 0.0 4.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EGG00479.1 - 0.081 12.8 0.2 4.7 7.2 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat SNARE PF05739.14 EGG00480.1 - 2.6e-14 52.6 6.1 2.6e-14 52.6 4.3 2.4 3 0 0 3 3 2 1 SNARE domain Syntaxin PF00804.20 EGG00480.1 - 7.5e-09 35.6 11.8 2.9e-08 33.8 0.9 2.3 2 0 0 2 2 2 1 Syntaxin IFT46_B_C PF12317.3 EGG00480.1 - 0.012 14.9 1.2 0.49 9.7 0.2 2.2 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Flu_NS2 PF00601.14 EGG00480.1 - 0.017 15.3 4.2 0.22 11.7 0.1 2.6 3 0 0 3 3 2 0 Influenza non-structural protein (NS2) MCPsignal PF00015.16 EGG00480.1 - 0.038 13.5 19.2 0.023 14.2 5.8 2.9 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-6_N PF09177.6 EGG00480.1 - 0.053 13.9 12.8 4.3 7.8 0.0 3.8 2 1 2 4 4 4 0 Syntaxin 6, N-terminal Retrotrans_gag PF03732.12 EGG00480.1 - 0.075 13.1 3.0 2.2 8.3 0.2 2.6 2 1 0 2 2 2 0 Retrotransposon gag protein Vac_Fusion PF02346.11 EGG00480.1 - 0.12 11.7 1.9 0.6 9.5 0.1 2.4 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Syntaxin_2 PF14523.1 EGG00480.1 - 0.14 12.1 11.9 0.14 12.2 2.8 2.8 2 2 0 2 2 2 0 Syntaxin-like protein RPA_C PF08784.6 EGG00480.1 - 0.31 11.4 3.8 0.29 11.5 1.3 1.9 2 0 0 2 2 2 0 Replication protein A C terminal DASH_Dam1 PF08653.5 EGG00480.1 - 0.33 10.7 2.0 6.7 6.5 0.0 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 AAA_13 PF13166.1 EGG00480.1 - 0.42 9.0 10.1 0.57 8.5 7.0 1.1 1 0 0 1 1 1 0 AAA domain DUF2203 PF09969.4 EGG00480.1 - 0.66 10.2 14.0 0.19 11.9 2.0 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) AATF-Che1 PF13339.1 EGG00480.1 - 0.77 9.9 8.9 5.3 7.1 1.5 2.9 2 2 1 3 3 3 0 Apoptosis antagonizing transcription factor DUF4559 PF15112.1 EGG00480.1 - 0.98 8.5 9.2 0.62 9.1 1.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4559) DUF1542 PF07564.6 EGG00480.1 - 1.1 9.3 6.5 1.4 9.0 1.3 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) BLOC1_2 PF10046.4 EGG00480.1 - 1.4 9.0 8.7 7.8 6.7 1.6 3.4 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PilJ PF13675.1 EGG00480.1 - 1.8 8.9 11.5 1.4 9.2 1.7 2.8 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Rho_Binding PF08912.6 EGG00480.1 - 2.2 8.6 8.2 0.95 9.8 1.1 2.9 2 1 1 3 3 3 0 Rho Binding FlaC_arch PF05377.6 EGG00480.1 - 2.6 8.0 9.8 5.1 7.0 0.9 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Cortex-I_coil PF09304.5 EGG00480.1 - 3.2 7.8 12.5 2.9 7.9 2.9 2.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF724 PF05266.9 EGG00480.1 - 5.2 6.6 13.1 1.1e+02 2.2 9.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.7 EGG00480.1 - 7.7 6.3 11.4 2.8 7.7 2.2 3.1 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Rabaptin PF03528.10 EGG00480.1 - 7.7 6.4 17.1 11 5.9 7.5 3.1 2 1 1 3 3 3 0 Rabaptin LIM PF00412.17 EGG00481.1 - 1.8e-13 50.3 22.9 2.4e-11 43.5 2.6 3.8 4 0 0 4 4 4 3 LIM domain zf-CCHC PF00098.18 EGG00482.1 - 2.2e-05 24.1 3.2 3.4e-05 23.5 2.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGG00482.1 - 0.018 14.6 0.4 0.04 13.5 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Trypan_PARP PF05887.6 EGG00482.1 - 2.6 7.8 9.6 3.6 7.4 6.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-CCHC PF00098.18 EGG00484.1 - 2.4e-05 24.0 1.5 4.2e-05 23.2 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle DivIC PF04977.10 EGG00484.1 - 8.7 5.9 7.1 21 4.6 1.1 2.7 1 1 1 2 2 2 0 Septum formation initiator Glycos_transf_2 PF00535.21 EGG00485.1 - 0.0086 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 F5_F8_type_C PF00754.20 EGG00485.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain IU_nuc_hydro PF01156.14 EGG00488.1 - 7.5e-06 25.3 0.0 2.3e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Inosine-uridine preferring nucleoside hydrolase Acyl-CoA_dh_1 PF00441.19 EGG00489.1 - 5e-24 85.1 0.0 8.1e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGG00489.1 - 1.9e-20 73.4 0.0 3.8e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGG00489.1 - 2.4e-17 62.1 0.2 4.6e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGG00489.1 - 2.9e-07 30.7 0.0 6.2e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain VIT1 PF01988.14 EGG00490.1 - 1.2e-65 221.0 4.1 1.4e-65 220.7 2.9 1.1 1 0 0 1 1 1 1 VIT family CENP-B_dimeris PF09026.5 EGG00491.1 - 0.96 9.7 6.3 1.3 9.2 4.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 EGG00491.1 - 6.9 7.0 7.6 9.7 6.5 5.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EGG00491.1 - 8 5.9 7.9 11 5.5 5.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF3129 PF11327.3 EGG00492.1 - 3.5e-18 66.0 1.1 5.4e-18 65.4 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) DUF3129 PF11327.3 EGG00493.1 - 1.9e-11 44.1 0.0 3.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Alpha_kinase PF02816.13 EGG00495.1 - 5.9e-08 32.5 3.3 1.1e-07 31.7 2.3 1.4 1 0 0 1 1 1 1 Alpha-kinase family AFT PF08731.6 EGG00496.1 - 2.6e-06 27.5 0.4 5.5e-06 26.5 0.3 1.5 1 0 0 1 1 1 1 Transcription factor AFT FAR1 PF03101.10 EGG00496.1 - 0.00028 21.3 0.4 0.00063 20.2 0.3 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain X PF00739.14 EGG00496.1 - 0.0032 17.3 0.1 0.0074 16.2 0.1 1.6 2 0 0 2 2 2 1 Trans-activation protein X HEAT_2 PF13646.1 EGG00497.1 - 3.5e-12 46.4 2.2 0.033 14.4 0.0 5.5 6 0 0 6 6 6 4 HEAT repeats Arm PF00514.18 EGG00497.1 - 2.1e-10 40.0 6.9 0.17 11.7 0.0 7.7 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EGG00497.1 - 1.6e-08 33.9 7.0 0.0016 18.3 0.2 7.1 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 EGG00497.1 - 2.6e-08 34.1 4.6 0.00014 22.2 0.4 5.6 5 1 1 6 6 6 1 HEAT-like repeat V-ATPase_H_C PF11698.3 EGG00497.1 - 0.0025 17.7 0.3 0.23 11.3 0.0 3.6 3 0 0 3 3 3 1 V-ATPase subunit H CTNNBL PF08216.6 EGG00497.1 - 0.027 14.0 0.0 0.095 12.3 0.0 2.0 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear PCDO_beta_N PF12391.3 EGG00499.1 - 0.0063 15.9 0.1 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 Protocatechuate 3,4-dioxygenase beta subunit N terminal DUF1127 PF06568.6 EGG00500.1 - 0.055 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) BMP2K_C PF15282.1 EGG00501.1 - 0.047 13.8 0.0 0.062 13.4 0.0 1.1 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus HlyC PF02794.11 EGG00502.1 - 0.0034 16.9 1.3 0.19 11.3 0.4 2.4 2 0 0 2 2 2 2 RTX toxin acyltransferase family DUF466 PF04328.8 EGG00502.1 - 0.035 13.9 0.3 0.094 12.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF466) zf-CCHC_4 PF14392.1 EGG00504.1 - 0.19 11.4 2.3 0.33 10.6 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF1499 PF07386.6 EGG00505.1 - 0.083 13.0 0.1 0.12 12.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1499) CoA_binding_3 PF13727.1 EGG00506.1 - 0.078 12.8 0.1 0.078 12.8 0.1 1.1 1 0 0 1 1 1 0 CoA-binding domain Glyco_tranf_2_3 PF13641.1 EGG00507.1 - 2.5e-17 63.4 0.0 4.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGG00507.1 - 5.1e-08 32.3 0.0 9.3e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGG00507.1 - 1.2e-05 25.0 0.0 3e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EGG00507.1 - 0.00016 21.4 9.0 0.00016 21.4 6.3 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF1129 PF06570.6 EGG00507.1 - 0.084 12.1 2.7 1.2 8.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF1230 PF06799.6 EGG00507.1 - 0.8 9.5 5.0 14 5.5 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) UreF PF01730.11 EGG00508.1 - 3.1e-13 50.0 0.0 5.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 UreF BChl_A PF02327.12 EGG00508.1 - 0.1 11.1 0.0 0.23 10.0 0.0 1.5 1 0 0 1 1 1 0 Bacteriochlorophyll A protein DUF4355 PF14265.1 EGG00508.1 - 0.13 12.2 0.0 0.44 10.5 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4355) Cwf_Cwc_15 PF04889.7 EGG00510.1 - 1 8.9 40.9 0.82 9.3 14.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Band_7 PF01145.20 EGG00511.1 - 2.8e-31 108.7 4.2 4.1e-31 108.2 2.9 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EGG00511.1 - 0.0034 16.9 0.5 0.0056 16.2 0.4 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family GGDN PF05165.7 EGG00511.1 - 0.02 13.9 0.3 0.029 13.3 0.2 1.3 1 0 0 1 1 1 0 GGDN family DUF3354 PF11834.3 EGG00511.1 - 0.057 13.0 0.2 2.9 7.5 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3354) DUF1542 PF07564.6 EGG00512.1 - 0.033 14.2 1.2 0.065 13.2 0.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) EF-hand_1 PF00036.27 EGG00518.1 - 2.2e-26 89.1 13.4 2e-06 26.7 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGG00518.1 - 2.9e-24 84.9 3.8 7.2e-12 45.2 0.7 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGG00518.1 - 5e-20 69.8 13.5 5.4e-06 25.5 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EGG00518.1 - 6.4e-19 66.0 9.5 7.2e-05 22.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EGG00518.1 - 2.1e-15 56.0 11.8 3.9e-06 26.3 1.9 4.5 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGG00518.1 - 6.1e-06 26.2 0.1 0.014 15.3 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EGG00518.1 - 0.00058 19.7 0.2 0.04 13.8 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain EF-hand_4 PF12763.2 EGG00518.1 - 0.0011 18.6 9.0 0.079 12.7 0.3 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand Anthrax-tox_M PF09156.5 EGG00518.1 - 0.055 12.5 0.5 0.8 8.7 0.0 2.0 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain DUF3215 PF11503.3 EGG00518.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) A2M_N PF01835.14 EGG00520.1 - 0.078 13.2 0.1 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 MG2 domain Baculo_PEP_C PF04513.7 EGG00520.1 - 0.32 10.8 3.5 0.58 9.9 0.8 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_A_bac PF01000.21 EGG00521.1 - 1.1e-21 77.1 0.0 2.6e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGG00521.1 - 3.2e-14 51.7 0.0 4.3e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF771 PF05595.6 EGG00521.1 - 0.03 14.2 0.1 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF771) DAO PF01266.19 EGG00523.1 - 3e-31 108.6 0.0 3.7e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGG00523.1 - 0.0082 16.0 0.0 0.13 12.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ABG_transport PF03806.8 EGG00525.1 - 0.031 12.2 0.1 0.033 12.2 0.1 1.0 1 0 0 1 1 1 0 AbgT putative transporter family PCP PF02429.10 EGG00525.1 - 0.072 13.1 0.0 0.079 13.0 0.0 1.0 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein 3HCDH PF00725.17 EGG00526.1 - 1.4e-19 70.3 0.0 3e-19 69.1 0.0 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.13 EGG00526.1 - 7e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 EGG00527.1 - 2.6e-19 69.3 0.1 6.2e-16 58.3 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGG00527.1 - 2.4e-11 43.2 0.0 2.9e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase GatB_N PF02934.10 EGG00528.1 - 3.5e-107 357.5 0.0 5.7e-107 356.8 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EGG00528.1 - 3.7e-17 62.4 0.1 1.4e-14 54.0 0.1 2.3 1 1 0 1 1 1 1 GatB domain Ribonuclease_3 PF00636.21 EGG00529.1 - 0.00071 19.9 0.1 0.0018 18.6 0.0 1.6 2 0 0 2 2 2 1 Ribonuclease III domain TM2 PF05154.11 EGG00529.1 - 0.0009 19.4 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 TM2 domain DUF1145 PF06611.7 EGG00530.1 - 0.04 13.5 0.2 0.04 13.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) MerC PF03203.9 EGG00530.1 - 2.2 8.6 6.9 2.9 8.3 1.6 2.7 2 1 1 3 3 3 0 MerC mercury resistance protein DUF4064 PF13273.1 EGG00530.1 - 8.7 6.5 11.5 19 5.3 3.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) FH2 PF02181.18 EGG00531.1 - 0.08 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain Abhydrolase_6 PF12697.2 EGG00532.1 - 3.4e-32 112.1 0.0 4.5e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG00532.1 - 4.3e-18 65.7 0.0 2.3e-17 63.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG00532.1 - 2.6e-11 43.4 0.0 2.6e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGG00532.1 - 0.00045 20.0 0.0 0.0009 19.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EGG00532.1 - 0.0063 15.0 0.0 0.0096 14.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family NOG1 PF06858.9 EGG00533.1 - 3.4e-27 94.0 0.2 6.9e-27 93.0 0.2 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EGG00533.1 - 7.2e-22 76.8 0.9 8.5e-16 57.3 0.4 2.8 2 0 0 2 2 2 2 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EGG00533.1 - 2e-16 59.9 0.0 5.7e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGG00533.1 - 1.3e-08 34.2 0.0 3.9e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EGG00533.1 - 0.0058 17.1 0.0 0.022 15.2 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 EGG00533.1 - 0.017 14.8 0.5 0.47 10.1 0.0 3.4 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 EGG00533.1 - 0.026 13.6 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 AIG1 family DUF258 PF03193.11 EGG00533.1 - 0.036 13.2 0.0 0.32 10.1 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGG00533.1 - 0.068 12.9 2.8 3.8 7.3 0.0 3.4 3 1 1 4 4 4 0 Dynamin family Gag_spuma PF03276.9 EGG00535.1 - 0.13 10.6 5.5 0.16 10.2 3.8 1.2 1 0 0 1 1 1 0 Spumavirus gag protein AAA_23 PF13476.1 EGG00535.1 - 0.14 12.4 7.8 0.18 12.0 5.4 1.3 1 0 0 1 1 1 0 AAA domain DUF3464 PF11947.3 EGG00535.1 - 5.3 6.4 9.0 9.2 5.7 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) PGAP1 PF07819.8 EGG00538.1 - 3.6e-07 30.0 0.0 5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EGG00538.1 - 0.00073 18.8 0.1 0.0011 18.2 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Cutinase PF01083.17 EGG00538.1 - 0.066 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.2 EGG00538.1 - 0.087 12.6 0.0 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF904 PF06005.7 EGG00541.1 - 0.0019 18.4 9.3 0.031 14.5 0.7 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF904) CENP-N PF05238.8 EGG00541.1 - 0.043 12.8 3.9 0.069 12.1 0.2 2.0 2 0 0 2 2 2 0 Kinetochore protein CHL4 like VirE1 PF12189.3 EGG00541.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Single-strand DNA-binding protein Fib_alpha PF08702.5 EGG00541.1 - 0.3 11.1 2.3 1.7 8.7 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-H PF05837.7 EGG00541.1 - 0.32 11.1 7.6 0.29 11.3 0.6 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Pex19 PF04614.7 EGG00541.1 - 0.39 10.2 5.2 0.073 12.6 0.8 1.7 2 0 0 2 2 2 0 Pex19 protein family DUF972 PF06156.8 EGG00541.1 - 0.44 10.9 6.7 2 8.8 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 EGG00541.1 - 0.46 10.6 5.8 6.6 6.9 0.1 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4298 PF14131.1 EGG00541.1 - 0.59 10.0 4.7 8.8 6.2 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Vir_act_alpha_C PF10400.4 EGG00541.1 - 0.67 10.3 8.4 0.62 10.4 0.9 2.4 2 0 0 2 2 2 0 Virulence activator alpha C-term GrpE PF01025.14 EGG00541.1 - 0.7 9.4 10.4 1.2 8.6 0.8 2.2 2 0 0 2 2 2 0 GrpE Tropomyosin_1 PF12718.2 EGG00541.1 - 0.72 9.7 13.2 2.8 7.7 2.8 2.2 2 0 0 2 2 2 0 Tropomyosin like IncA PF04156.9 EGG00541.1 - 1.1 8.7 8.7 0.38 10.3 0.9 2.2 2 0 0 2 2 2 0 IncA protein MerR-DNA-bind PF09278.6 EGG00541.1 - 3.3 8.1 10.3 2.1 8.8 0.1 3.7 3 1 1 4 4 4 0 MerR, DNA binding bZIP_1 PF00170.16 EGG00541.1 - 4.5 7.2 7.2 1.5 8.8 0.3 2.6 2 1 0 2 2 2 0 bZIP transcription factor Prefoldin_2 PF01920.15 EGG00541.1 - 8.1 6.2 11.0 11 5.8 1.3 2.7 2 0 0 2 2 2 0 Prefoldin subunit DWNN PF08783.6 EGG00543.1 - 0.052 13.4 1.9 1.9 8.4 0.1 2.7 3 0 0 3 3 3 0 DWNN domain ExbD PF02472.11 EGG00543.1 - 0.21 11.5 7.9 0.3 11.0 1.1 2.7 1 1 1 3 3 3 0 Biopolymer transport protein ExbD/TolR JmjC PF02373.17 EGG00544.1 - 5e-13 49.3 0.0 8.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EGG00544.1 - 0.001 18.6 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 EGG00544.1 - 0.044 13.2 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Cupin domain SinI PF08671.5 EGG00544.1 - 1.1 8.7 7.3 1.3 8.4 0.0 3.5 4 0 0 4 4 4 0 Anti-repressor SinI MFS_1 PF07690.11 EGG00546.1 - 0.0083 14.8 7.1 0.025 13.2 0.0 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EGG00547.1 - 2.2e-27 95.7 30.2 2.7e-27 95.4 20.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EGG00548.1 - 3e-21 75.5 27.7 1.6e-18 66.5 8.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG00548.1 - 0.00021 20.0 24.5 0.0033 16.0 8.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter SQS_PSY PF00494.14 EGG00549.1 - 2.4e-40 138.4 0.0 3e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF872 PF05915.7 EGG00550.1 - 0.11 12.3 0.4 0.12 12.2 0.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF4389 PF14333.1 EGG00550.1 - 0.36 10.5 1.9 0.41 10.3 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) DUF4419 PF14388.1 EGG00552.1 - 0.021 14.0 0.2 0.06 12.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4419) DisA-linker PF10635.4 EGG00552.1 - 0.065 12.7 0.1 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region DUF4050 PF13259.1 EGG00558.1 - 6.5e-06 26.0 0.6 1.1e-05 25.3 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) Sporozoite_P67 PF05642.6 EGG00558.1 - 0.17 9.6 2.6 0.26 9.0 1.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Collagen PF01391.13 EGG00560.1 - 2.1e-05 23.9 14.3 7.6e-05 22.1 9.9 1.9 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF605 PF04652.11 EGG00560.1 - 0.083 12.2 19.9 0.15 11.4 13.8 1.4 1 0 0 1 1 1 0 Vta1 like DUF445 PF04286.7 EGG00562.1 - 0.0065 16.0 2.2 0.0074 15.8 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF2236 PF09995.4 EGG00563.1 - 2.7e-12 46.4 0.0 4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) zf-CCCH PF00642.19 EGG00564.1 - 2.5e-18 65.3 20.8 1.2e-11 44.0 1.9 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WAP PF00095.16 EGG00564.1 - 2.6 8.0 7.4 0.84 9.6 1.3 2.2 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Omega-toxin PF06357.6 EGG00564.1 - 3.2 7.4 6.1 1.2 8.7 1.2 2.3 2 0 0 2 2 2 0 Omega-atracotoxin zf-CCHH PF10283.4 EGG00564.1 - 3.7 7.4 9.8 0.82 9.5 1.6 3.0 2 1 1 3 3 3 0 Zinc-finger (CX5CX6HX5H) motif AMP-binding PF00501.23 EGG00565.1 - 9.5e-28 96.7 0.0 3e-27 95.0 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EGG00565.1 - 0.00073 19.7 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Sdh5 PF03937.11 EGG00567.1 - 0.047 13.3 0.1 3.2 7.5 0.0 3.1 3 0 0 3 3 3 0 Flavinator of succinate dehydrogenase LRR_4 PF12799.2 EGG00568.1 - 9.8e-13 47.4 11.8 0.096 12.3 0.5 6.9 6 0 0 6 6 6 5 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EGG00568.1 - 6.3e-11 41.8 1.4 6.3e-11 41.8 1.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EGG00568.1 - 2.3e-08 33.2 18.5 1 9.6 0.4 9.2 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.28 EGG00568.1 - 1.9e-06 27.0 22.3 5 7.5 0.0 9.7 10 2 1 11 11 11 2 Leucine Rich Repeat LRR_7 PF13504.1 EGG00568.1 - 0.00016 21.3 17.9 11 6.7 0.0 9.4 10 0 0 10 10 10 1 Leucine rich repeat F-box PF00646.28 EGG00568.1 - 0.028 14.0 4.8 0.043 13.4 0.5 3.0 2 0 0 2 2 2 0 F-box domain Gag_p12 PF01141.13 EGG00569.1 - 0.28 11.3 1.9 0.2 11.7 0.2 1.6 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 NOA36 PF06524.7 EGG00569.1 - 1.2 8.3 5.9 1.5 8.0 4.1 1.1 1 0 0 1 1 1 0 NOA36 protein ORC6 PF05460.8 EGG00569.1 - 1.6 7.7 4.4 1.9 7.5 3.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PPR_2 PF13041.1 EGG00573.1 - 2.4e-10 40.2 0.3 0.00012 21.9 0.0 5.0 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.15 EGG00573.1 - 6.6e-05 22.6 0.1 12 6.1 0.0 4.6 5 0 0 5 5 5 3 PPR repeat NCA2 PF08637.5 EGG00574.1 - 2.2e-50 171.2 3.4 3.9e-25 88.3 1.2 2.3 2 0 0 2 2 2 2 ATP synthase regulation protein NCA2 ERGIC_N PF13850.1 EGG00574.1 - 0.0035 17.2 1.0 0.13 12.2 0.0 3.0 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) UBN2_3 PF14244.1 EGG00577.1 - 0.0091 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4661 PF15576.1 EGG00577.1 - 1.7 8.2 6.2 3.8 7.0 4.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Phage_int_SAM_1 PF02899.12 EGG00578.1 - 0.099 12.8 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Bse634I PF07832.6 EGG00578.1 - 0.14 11.2 0.5 0.34 10.0 0.0 1.7 2 0 0 2 2 2 0 Cfr10I/Bse634I restriction endonuclease DUF4604 PF15377.1 EGG00582.1 - 2.7e-11 43.9 21.5 5e-07 30.0 11.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4604) Sua5_yciO_yrdC PF01300.13 EGG00583.1 - 2.1e-53 180.2 0.0 3.2e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EGG00583.1 - 3.2e-22 78.9 0.0 4.9e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Tetrabrachion PF11401.3 EGG00585.1 - 0.092 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Tetrabrachion Ribosomal_L1 PF00687.16 EGG00586.1 - 1.5e-51 174.8 2.3 1.8e-51 174.6 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family LRR_8 PF13855.1 EGG00588.1 - 5.5e-06 26.0 6.6 0.013 15.2 0.0 3.9 3 1 1 4 4 4 3 Leucine rich repeat LRR_5 PF13306.1 EGG00588.1 - 2.6e-05 23.9 1.7 0.057 13.1 0.2 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_4 PF12799.2 EGG00588.1 - 0.044 13.4 5.5 4.2 7.0 0.6 4.4 3 1 0 4 4 4 0 Leucine Rich repeats (2 copies) WD40 PF00400.27 EGG00589.1 - 1e-12 47.4 3.2 0.019 14.8 0.1 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Glyco_hydro_101 PF12905.2 EGG00590.1 - 0.086 11.4 0.4 0.93 8.0 0.1 1.9 1 1 1 2 2 2 0 Endo-alpha-N-acetylgalactosaminidase AAA_12 PF13087.1 EGG00591.1 - 1.4e-53 181.2 0.3 7.7e-53 178.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EGG00591.1 - 4.4e-49 167.1 0.6 1.3e-48 165.6 0.4 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGG00591.1 - 1.4e-11 43.9 0.1 4.8e-11 42.2 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EGG00591.1 - 7.1e-11 42.0 0.0 5.2e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EGG00591.1 - 1.3e-05 24.8 0.7 0.35 10.3 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EGG00591.1 - 0.02 14.5 0.1 1 8.9 0.1 2.6 1 1 0 1 1 1 0 Helicase UvrD_C_2 PF13538.1 EGG00591.1 - 0.08 13.0 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.24 EGG00591.1 - 0.13 12.5 0.1 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad21_Rec8_N PF04825.8 EGG00593.1 - 3.8e-22 78.3 0.0 6.8e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EGG00593.1 - 7.7e-07 28.2 0.0 1.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF1374 PF07118.6 EGG00593.1 - 0.13 12.3 2.6 0.32 11.1 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) Mito_fiss_reg PF05308.6 EGG00594.1 - 2.4 7.4 18.3 0.043 13.1 5.4 2.0 1 1 1 2 2 2 0 Mitochondrial fission regulator PRELI PF04707.9 EGG00596.1 - 2.5e-30 105.1 0.0 3.4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family Leu_zip PF15294.1 EGG00596.1 - 0.0047 16.0 0.2 0.009 15.1 0.1 1.6 1 1 0 1 1 1 1 Leucine zipper DUF16 PF01519.11 EGG00601.1 - 0.048 13.8 0.5 11 6.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4295 PF14128.1 EGG00602.1 - 0.075 12.6 0.7 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) NPV_P10 PF05531.7 EGG00602.1 - 0.18 12.0 2.1 0.4 10.9 0.8 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.1 EGG00606.1 - 2.8 6.8 10.9 3.8 6.3 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UBX PF00789.15 EGG00607.1 - 0.0003 20.7 0.0 0.0013 18.7 0.0 2.0 1 1 0 1 1 1 1 UBX domain UBA PF00627.26 EGG00607.1 - 0.056 13.3 0.0 0.25 11.2 0.0 2.2 1 0 0 1 1 1 0 UBA/TS-N domain Suc_Fer-like PF06999.7 EGG00607.1 - 0.45 10.4 3.5 0.42 10.5 1.7 1.5 1 1 0 1 1 1 0 Sucrase/ferredoxin-like Ric8 PF10165.4 EGG00608.1 - 0.05 12.4 0.1 0.07 11.9 0.1 1.1 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn E1-E2_ATPase PF00122.15 EGG00609.1 - 1.9e-21 76.1 0.1 2.9e-20 72.2 0.0 2.6 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGG00609.1 - 7.5e-18 65.7 0.0 2.1e-16 60.9 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGG00609.1 - 9.2e-10 38.9 0.1 2.3e-09 37.6 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGG00609.1 - 1.4e-06 28.1 0.0 4.4e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGG00609.1 - 0.0022 17.6 0.0 0.0057 16.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FKBP_C PF00254.23 EGG00609.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase Spore_YhaL PF14147.1 EGG00609.1 - 0.13 11.7 3.6 0.056 12.9 0.2 2.1 2 0 0 2 2 2 0 Sporulation protein YhaL HCNGP PF07818.8 EGG00613.1 - 1.9e-25 88.7 0.4 3.9e-25 87.7 0.3 1.4 1 0 0 1 1 1 1 HCNGP-like protein PRP38_assoc PF12871.2 EGG00613.1 - 0.00044 20.7 26.2 0.0011 19.4 18.1 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term NIF3 PF01784.13 EGG00615.1 - 2.4e-59 200.8 0.0 3e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Chordopox_L2 PF05803.7 EGG00615.1 - 0.068 12.8 0.1 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus L2 protein Glyco_hydro_7 PF00840.15 EGG00616.1 - 1.8e-195 649.4 16.1 2.1e-195 649.1 11.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 PBP_sp32 PF07222.7 EGG00616.1 - 0.05 12.7 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 UPF0242 PF06785.6 EGG00618.1 - 0.011 14.4 0.6 0.015 13.9 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Lzipper-MIP1 PF14389.1 EGG00618.1 - 0.015 15.3 3.0 0.31 11.1 0.2 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 HSBP1 PF06825.7 EGG00618.1 - 0.037 13.5 1.3 6.4 6.4 0.0 2.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF342 PF03961.8 EGG00618.1 - 0.17 10.2 4.2 0.23 9.8 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EGG00618.1 - 0.2 11.2 8.1 0.37 10.3 5.6 1.4 1 0 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 EGG00618.1 - 0.39 10.6 2.8 18 5.3 0.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.7 EGG00618.1 - 0.71 10.2 8.8 2.1 8.7 1.7 3.2 2 1 1 3 3 3 0 SlyX TSC22 PF01166.13 EGG00618.1 - 0.82 9.6 4.6 15 5.6 0.1 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family Tropomyosin_1 PF12718.2 EGG00618.1 - 1 9.1 10.6 2.4 7.9 5.6 2.4 1 1 1 2 2 2 0 Tropomyosin like YlbD_coat PF14071.1 EGG00618.1 - 4.4 7.3 7.5 0.85 9.6 2.3 2.0 2 0 0 2 2 2 0 Putative coat protein ABC_tran PF00005.22 EGG00619.1 - 1.1e-15 58.0 0.1 4.2e-15 56.2 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGG00619.1 - 2.5e-10 40.8 0.9 0.00044 20.2 0.4 2.2 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EGG00619.1 - 5.6e-07 28.9 0.0 0.011 14.8 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EGG00619.1 - 0.00026 20.4 0.1 0.00053 19.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EGG00619.1 - 0.00086 18.7 0.7 0.0021 17.4 0.0 2.1 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 EGG00619.1 - 0.0025 17.3 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EGG00619.1 - 0.0062 16.2 0.3 0.086 12.5 0.0 2.2 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 EGG00619.1 - 0.0074 15.5 0.2 2.2 7.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EGG00619.1 - 0.023 14.6 0.0 0.052 13.5 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 EGG00619.1 - 0.027 13.6 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGG00619.1 - 0.038 13.9 1.2 0.048 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EGG00619.1 - 0.045 13.7 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGG00619.1 - 0.045 14.5 0.4 0.097 13.4 0.3 2.0 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EGG00619.1 - 0.045 14.2 0.0 0.075 13.5 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein Arf PF00025.16 EGG00619.1 - 0.048 12.8 0.1 0.099 11.8 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_23 PF13476.1 EGG00619.1 - 0.052 13.8 0.0 0.077 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGG00619.1 - 0.06 13.2 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGG00619.1 - 0.11 12.6 0.3 0.36 10.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.1 EGG00619.1 - 0.13 10.6 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2423 PF10338.4 EGG00621.1 - 1.5e-14 53.7 8.6 2.2e-14 53.1 6.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Spore_coat_CotO PF14153.1 EGG00621.1 - 0.0018 17.7 3.8 0.0018 17.7 2.6 1.0 1 0 0 1 1 1 1 Spore coat protein CotO Enoyl_reductase PF12241.3 EGG00621.1 - 0.067 12.1 0.4 0.071 12.0 0.3 1.1 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Laps PF10169.4 EGG00621.1 - 1.8 8.7 11.9 3.5 7.8 8.2 1.5 1 1 0 1 1 1 0 Learning-associated protein DUF2146 PF10220.4 EGG00621.1 - 2.3 6.0 4.8 2.6 5.9 3.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) GalKase_gal_bdg PF10509.4 EGG00622.1 - 7.2e-20 70.0 0.2 1.4e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EGG00622.1 - 6.8e-11 42.2 0.0 1.5e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EGG00622.1 - 2.4e-10 40.3 0.1 5.5e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF4448 PF14610.1 EGG00624.1 - 0.039 13.4 0.0 0.039 13.4 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4448) HGTP_anticodon2 PF12745.2 EGG00624.1 - 0.25 10.4 14.1 0.48 9.5 9.8 1.5 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs zf-C2H2 PF00096.21 EGG00624.1 - 4.5 7.8 5.6 7.9 7.0 0.3 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Alpha_kinase PF02816.13 EGG00625.1 - 2.9e-24 85.7 0.2 3.8e-24 85.3 0.2 1.2 1 0 0 1 1 1 1 Alpha-kinase family Mucin PF01456.12 EGG00626.1 - 0.0045 16.7 4.6 0.007 16.1 3.2 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3439 PF11921.3 EGG00626.1 - 0.74 9.5 6.3 1.4 8.7 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Melibiase PF02065.13 EGG00627.1 - 2e-29 102.5 0.1 1.1e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 Melibiase Glyco_hydro_3 PF00933.16 EGG00630.1 - 1.5e-84 283.4 0.0 2.3e-84 282.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGG00630.1 - 4.4e-54 183.4 0.0 9.8e-54 182.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGG00630.1 - 1.2e-19 69.9 0.0 3.5e-19 68.5 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain Pico_P2B PF01552.12 EGG00630.1 - 0.021 14.9 0.0 0.11 12.6 0.0 2.2 1 1 0 1 1 1 0 Picornavirus 2B protein DASH_Dad3 PF08656.5 EGG00631.1 - 0.043 13.4 0.6 1.7 8.3 0.0 2.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 Tropomodulin PF03250.9 EGG00631.1 - 0.051 13.0 0.4 0.12 11.8 0.3 1.6 1 0 0 1 1 1 0 Tropomodulin Bac_rhodopsin PF01036.13 EGG00632.1 - 1.9e-47 161.4 18.1 2.7e-47 160.9 12.6 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2754 PF10953.3 EGG00632.1 - 7.3 6.7 9.4 4.6 7.3 3.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2754) Rhodanese PF00581.15 EGG00633.1 - 2.8e-13 50.2 0.0 3.4e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain PCI PF01399.22 EGG00634.1 - 2.7e-08 34.0 1.4 1.1e-07 32.1 0.1 2.6 2 0 0 2 2 2 1 PCI domain Abhydrolase_6 PF12697.2 EGG00639.1 - 7.2e-10 39.1 0.1 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG00639.1 - 1e-06 28.4 0.1 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Dak1 PF02733.12 EGG00640.1 - 5.9e-108 360.2 2.7 8.1e-108 359.8 1.9 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EGG00640.1 - 2.2e-36 125.1 0.7 2.2e-36 125.1 0.5 2.2 3 0 0 3 3 3 1 DAK2 domain Ppx-GppA PF02541.11 EGG00642.1 - 0.098 11.8 0.3 0.2 10.8 0.2 1.5 1 0 0 1 1 1 0 Ppx/GppA phosphatase family CW_binding_1 PF01473.15 EGG00643.1 - 0.69 10.1 2.6 1.6 8.9 1.8 1.7 1 0 0 1 1 1 0 Putative cell wall binding repeat DUF3102 PF11300.3 EGG00645.1 - 0.12 12.3 0.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3102) CW_binding_1 PF01473.15 EGG00645.1 - 1.4 9.1 4.3 3.2 8.0 3.0 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat V-SNARE_C PF12352.3 EGG00646.1 - 9.6e-16 57.6 0.8 2.6e-15 56.2 0.6 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EGG00646.1 - 0.00081 19.0 2.1 0.0045 16.6 0.0 2.8 2 2 1 3 3 3 1 Sec20 BBP1_C PF15272.1 EGG00646.1 - 0.17 11.4 4.3 0.55 9.7 0.5 2.3 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal CEP19 PF14933.1 EGG00646.1 - 0.2 11.9 1.7 0.28 11.4 0.2 1.8 1 1 1 2 2 2 0 CEP19-like protein DUF2408 PF10303.4 EGG00646.1 - 0.21 11.6 2.3 0.32 11.1 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Rabaptin PF03528.10 EGG00646.1 - 0.7 9.8 3.6 0.85 9.5 1.0 2.2 2 1 0 2 2 2 0 Rabaptin AATF-Che1 PF13339.1 EGG00646.1 - 1.3 9.1 5.9 12 6.0 0.1 2.7 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor BLOC1_2 PF10046.4 EGG00646.1 - 2.1 8.5 5.1 4.2 7.5 0.2 2.9 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Transp_cyt_pur PF02133.10 EGG00647.1 - 3.4e-40 137.9 30.0 4.6e-40 137.4 20.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_hydro_18 PF00704.23 EGG00648.1 - 9.3e-64 216.0 0.2 1.1e-63 215.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_S10 PF00450.17 EGG00649.1 - 1.5e-73 248.3 0.1 5.9e-73 246.4 0.1 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase COesterase PF00135.23 EGG00650.1 - 6.6e-83 279.2 0.0 7.8e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EGG00650.1 - 0.0018 17.5 0.1 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EGG00650.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Spectrin PF00435.16 EGG00651.1 - 0.097 12.9 2.1 0.32 11.2 0.4 2.1 1 1 1 2 2 2 0 Spectrin repeat Ndc1_Nup PF09531.5 EGG00653.1 - 0.14 10.5 4.3 0.33 9.3 3.0 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Myb_DNA-bind_6 PF13921.1 EGG00654.1 - 0.025 14.6 0.6 0.025 14.6 0.4 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain zf-CCCH PF00642.19 EGG00655.1 - 1.1e-10 40.9 18.7 4.1e-06 26.3 1.5 4.4 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DnaJ PF00226.26 EGG00656.1 - 7.7e-20 70.4 0.5 1.8e-19 69.2 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain DUF724 PF05266.9 EGG00656.1 - 0.011 15.3 11.2 0.019 14.5 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Gon7 PF08738.5 EGG00657.1 - 0.029 14.3 0.5 0.036 14.0 0.3 1.3 1 1 0 1 1 1 0 Gon7 family CppA_N PF14506.1 EGG00659.1 - 0.015 14.9 1.0 0.034 13.8 0.1 1.9 2 0 0 2 2 2 0 CppA N-terminal HALZ PF02183.13 EGG00659.1 - 0.072 12.8 0.1 0.2 11.3 0.1 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 EGG00659.1 - 0.2 11.3 6.7 0.41 10.3 4.6 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 EGG00659.1 - 0.9 7.3 6.8 1.3 6.7 4.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EGG00659.1 - 1.5 8.3 4.8 0.42 10.1 0.3 2.2 2 0 0 2 2 2 0 Septum formation initiator NPV_P10 PF05531.7 EGG00659.1 - 2.4 8.4 7.5 2.7 8.3 2.9 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.7 EGG00659.1 - 4.4 7.7 6.9 3.6 8.0 1.8 2.6 2 0 0 2 2 2 0 SlyX MafB19-deam PF14437.1 EGG00660.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 MafB19-like deaminase Acyl_transf_1 PF00698.16 EGG00661.1 - 4.9e-55 187.0 0.0 6e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain DUF4325 PF14213.1 EGG00661.1 - 0.015 14.9 0.0 0.081 12.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4325) ketoacyl-synt PF00109.21 EGG00662.1 - 1.5e-26 93.3 0.2 2.5e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EGG00662.1 - 1.7e-17 63.9 0.0 3e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EGG00662.1 - 1.5e-15 56.9 0.1 3.9e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EGG00662.1 - 5.1e-15 55.3 0.6 1.1e-13 51.0 0.0 2.7 2 1 1 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EGG00662.1 - 0.00026 20.9 0.0 0.00057 19.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG00662.1 - 0.0038 16.9 0.0 0.0087 15.7 0.0 1.6 1 0 0 1 1 1 1 KR domain Synaptobrevin PF00957.16 EGG00663.1 - 0.008 15.7 1.1 0.02 14.4 0.7 1.6 1 0 0 1 1 1 1 Synaptobrevin Baculo_PEP_C PF04513.7 EGG00663.1 - 0.25 11.1 5.6 0.39 10.5 2.9 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol PF00940.14 EGG00664.1 - 2.2e-150 500.6 0.0 3e-150 500.2 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EGG00664.1 - 7.3e-50 170.0 0.1 1.2e-49 169.3 0.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Thg1C PF14413.1 EGG00665.1 - 2.9e-41 139.9 0.1 4.3e-41 139.4 0.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EGG00665.1 - 6e-38 129.5 0.0 4.6e-37 126.6 0.0 2.1 1 1 0 1 1 1 1 tRNAHis guanylyltransferase F-box-like PF12937.2 EGG00666.1 - 0.041 13.6 2.1 0.82 9.4 0.0 3.4 3 2 0 3 3 3 0 F-box-like Ribosomal_L13 PF00572.13 EGG00667.1 - 0.097 12.7 0.3 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L13 Alpha_kinase PF02816.13 EGG00668.1 - 2.1e-12 47.1 0.0 3.3e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Lyase_8_N PF08124.6 EGG00669.1 - 0.031 13.1 0.1 0.075 11.8 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain FAP PF07174.6 EGG00670.1 - 0.92 8.7 8.0 1 8.5 5.6 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) ORC6 PF05460.8 EGG00670.1 - 7.1 5.6 10.2 9.2 5.2 7.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Mit_KHE1 PF10173.4 EGG00673.1 - 0.088 12.6 2.1 0.1 12.4 1.4 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related PIH1 PF08190.7 EGG00678.1 - 0.48 9.8 11.5 0.54 9.6 8.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Med13_C PF06333.7 EGG00678.1 - 1.1 7.6 7.3 1.3 7.5 5.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal GAGA_bind PF06217.7 EGG00678.1 - 2.5 7.9 10.6 2.8 7.8 7.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2413 PF10310.4 EGG00678.1 - 2.8 6.6 13.8 3.3 6.4 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SRP-alpha_N PF04086.8 EGG00678.1 - 3.2 7.0 11.5 3.7 6.8 7.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Peptidase_S30 PF01577.11 EGG00678.1 - 4.8 6.5 12.4 5.6 6.2 8.6 1.0 1 0 0 1 1 1 0 Potyvirus P1 protease DUF572 PF04502.8 EGG00678.1 - 9.4 5.3 12.9 10 5.2 9.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Paralemmin PF03285.10 EGG00679.1 - 0.0011 18.5 5.2 0.036 13.5 2.5 2.4 2 0 0 2 2 2 1 Paralemmin Tropomyosin_1 PF12718.2 EGG00679.1 - 0.11 12.2 15.4 0.79 9.5 10.6 2.1 1 1 0 1 1 1 0 Tropomyosin like bZIP_1 PF00170.16 EGG00679.1 - 0.29 11.1 10.1 1.8 8.5 1.9 2.9 3 0 0 3 3 3 0 bZIP transcription factor Viral_P18 PF04521.8 EGG00679.1 - 0.33 10.3 6.4 0.11 11.9 0.6 2.3 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Ax_dynein_light PF10211.4 EGG00679.1 - 0.66 9.7 11.3 1.3 8.8 5.9 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain Caudo_TAP PF02413.12 EGG00679.1 - 0.89 9.7 5.7 5.1 7.2 4.0 2.1 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF904 PF06005.7 EGG00679.1 - 2.8 8.3 11.2 4.1 7.7 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 EGG00679.1 - 3.6 5.3 6.0 4.8 4.8 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TSC22 PF01166.13 EGG00679.1 - 5.5 7.0 8.7 4.2 7.4 1.8 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.10 EGG00679.1 - 7.5 6.4 9.5 11 5.8 2.6 2.6 2 0 0 2 2 2 0 Basic region leucine zipper BLYB PF05289.6 EGG00683.1 - 0.091 12.5 0.8 0.95 9.2 0.3 2.4 1 1 2 3 3 3 0 Borrelia hemolysin accessory protein Fib_alpha PF08702.5 EGG00683.1 - 0.12 12.5 0.6 0.18 11.9 0.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Pkinase PF00069.20 EGG00684.1 - 1.6e-67 227.4 0.0 1.9e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG00684.1 - 1.8e-33 115.7 0.0 2.5e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG00684.1 - 9.8e-06 24.7 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGG00684.1 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGG00684.1 - 0.069 12.8 0.1 0.68 9.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Neuro_bHLH PF12533.3 EGG00684.1 - 0.51 11.1 0.0 0.51 11.1 0.0 2.5 2 1 1 3 3 3 0 Neuronal helix-loop-helix transcription factor DUF367 PF04034.8 EGG00686.1 - 1.2e-44 150.9 0.0 1.5e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EGG00686.1 - 1.8e-14 53.0 0.0 3e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Cyclin_N PF00134.18 EGG00687.1 - 6.3e-08 32.2 0.0 1.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EGG00687.1 - 8e-08 32.8 0.7 1.2e-07 32.3 0.0 1.6 2 0 0 2 2 2 1 Cyclin WD40 PF00400.27 EGG00688.1 - 3.4e-15 55.2 17.1 0.013 15.4 0.3 8.2 7 1 1 8 8 8 5 WD domain, G-beta repeat Macoilin PF09726.4 EGG00688.1 - 1.3 7.1 8.6 1.7 6.8 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein TPT PF03151.11 EGG00689.1 - 7.1e-11 41.9 26.3 8.2e-11 41.7 9.3 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EGG00689.1 - 6.3e-07 29.4 37.9 0.00088 19.3 11.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EGG00689.1 - 5.5e-06 25.5 21.7 7.9e-06 24.9 15.0 1.2 1 0 0 1 1 1 1 UAA transporter family Glyco_trans_1_2 PF13524.1 EGG00690.1 - 0.0017 18.5 0.0 0.007 16.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 FKS1_dom1 PF14288.1 EGG00692.1 - 3.6e-16 59.1 1.4 7.9e-08 32.2 0.3 2.5 1 1 1 2 2 2 2 1,3-beta-glucan synthase subunit FKS1, domain-1 adh_short PF00106.20 EGG00693.1 - 8.7e-32 110.3 0.5 1.2e-31 109.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG00693.1 - 3.6e-14 52.8 0.2 4.7e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGG00693.1 - 1.5e-12 47.8 0.0 1.8e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGG00693.1 - 1.5e-07 31.1 0.1 2e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGG00693.1 - 0.00015 21.4 0.1 0.0003 20.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EGG00693.1 - 0.0007 18.5 0.2 0.00085 18.3 0.1 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGG00693.1 - 0.0012 18.9 1.6 0.0046 16.9 1.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 EGG00693.1 - 0.0038 16.9 0.7 0.0061 16.2 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PELOTA_1 PF15608.1 EGG00693.1 - 0.005 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 PELOTA RNA binding domain THF_DHG_CYH_C PF02882.14 EGG00693.1 - 0.0052 15.8 0.2 0.059 12.4 0.0 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 EGG00693.1 - 0.026 13.6 0.1 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EGG00693.1 - 0.045 13.4 0.1 0.074 12.7 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ADH_zinc_N PF00107.21 EGG00693.1 - 0.068 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Helicase_RecD PF05127.9 EGG00693.1 - 0.069 12.7 0.3 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Helicase NmrA PF05368.8 EGG00693.1 - 0.12 11.6 0.2 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.15 EGG00693.1 - 0.13 12.3 0.2 0.25 11.4 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Meth_synt_2 PF01717.13 EGG00694.1 - 4.2e-138 459.7 0.1 3.7e-134 446.7 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EGG00694.1 - 7.9e-110 366.9 0.0 3.2e-101 338.6 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EGG00694.1 - 3.3e-07 29.5 0.0 0.0088 14.9 0.0 3.2 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) DUF4477 PF14780.1 EGG00695.1 - 0.088 12.1 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Herpes_UL55 PF04537.7 EGG00696.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL55 protein F-box-like PF12937.2 EGG00697.1 - 0.0026 17.4 0.1 0.013 15.2 0.1 2.2 1 1 0 1 1 1 1 F-box-like PRANC PF09372.5 EGG00697.1 - 0.0059 16.5 8.5 0.0059 16.5 5.9 3.0 2 1 0 2 2 2 1 PRANC domain Choline_kin_N PF04428.9 EGG00697.1 - 0.035 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Choline kinase N terminus RP-C_C PF11800.3 EGG00697.1 - 3.1 7.4 6.2 6.9 6.3 4.3 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region Bac_rhodopsin PF01036.13 EGG00698.1 - 2e-49 167.9 21.7 2.4e-49 167.6 15.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3792 PF12670.2 EGG00698.1 - 0.031 14.1 1.6 0.031 14.1 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) MRVI1 PF05781.7 EGG00698.1 - 0.1 10.9 0.2 0.16 10.3 0.1 1.2 1 0 0 1 1 1 0 MRVI1 protein DUF575 PF04746.7 EGG00698.1 - 0.28 11.2 1.6 0.67 10.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF575) C1-set PF07654.10 EGG00700.1 - 0.057 13.4 0.2 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin C1-set domain 3-alpha PF03475.9 EGG00700.1 - 0.17 11.5 0.6 0.33 10.6 0.4 1.5 1 0 0 1 1 1 0 3-alpha domain Frag1 PF10277.4 EGG00701.1 - 0.027 13.9 0.7 0.04 13.4 0.5 1.1 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family zf-C2H2 PF00096.21 EGG00702.1 - 8.9e-05 22.6 10.2 0.021 15.1 0.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG00702.1 - 0.00013 22.0 2.5 0.09 13.1 0.1 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGG00702.1 - 0.52 10.7 7.3 3.6 8.0 0.8 3.1 2 0 0 2 2 2 0 Zinc-finger double domain Tubulin PF00091.20 EGG00705.1 - 2e-69 233.7 0.0 2.6e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGG00705.1 - 2.3e-47 160.1 0.0 3.7e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGG00705.1 - 0.00031 20.2 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Mei5 PF10376.4 EGG00707.1 - 0.067 12.7 0.1 0.081 12.4 0.1 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein PAS_9 PF13426.1 EGG00708.1 - 4.5e-07 30.1 0.0 0.0061 16.9 0.0 2.7 2 0 0 2 2 2 2 PAS domain 2OG-FeII_Oxy_2 PF13532.1 EGG00709.1 - 1.1e-19 71.0 0.0 1.6e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UBA PF00627.26 EGG00709.1 - 0.018 14.8 0.0 0.066 13.0 0.0 1.9 2 0 0 2 2 2 0 UBA/TS-N domain CUE PF02845.11 EGG00709.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 CUE domain Gti1_Pac2 PF09729.4 EGG00710.1 - 3.5e-37 127.8 1.5 1.9e-34 118.9 0.1 3.5 2 1 1 3 3 3 2 Gti1/Pac2 family Sld5 PF05916.6 EGG00710.1 - 0.018 15.2 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 GINS complex protein zf-C2H2 PF00096.21 EGG00714.1 - 0.4 11.1 18.7 1.2 9.6 0.3 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type HMA PF00403.21 EGG00717.1 - 2.3e-13 50.0 2.0 2.8e-13 49.7 1.4 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Ribosomal_S21e PF01249.13 EGG00722.1 - 3.8e-38 129.2 0.0 4.2e-38 129.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e LRR_8 PF13855.1 EGG00723.1 - 5.8 6.7 13.6 1.3 8.8 1.8 4.0 4 1 0 4 4 4 0 Leucine rich repeat TypeIII_RM_meth PF12564.3 EGG00724.1 - 0.81 9.7 6.1 6 6.9 0.6 3.1 2 1 1 3 3 3 0 Type III restriction/modification enzyme methylation subunit LRR_4 PF12799.2 EGG00724.1 - 4.2 7.1 8.6 12 5.6 2.8 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) GDC-P PF02347.11 EGG00725.1 - 1.7e-181 603.6 0.0 1.9e-169 563.9 0.0 2.9 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EGG00725.1 - 9.7e-05 21.6 0.1 0.00018 20.7 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase RNase_Zc3h12a_2 PF14626.1 EGG00725.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain PPC PF04151.10 EGG00726.1 - 0.048 14.6 0.6 0.11 13.5 0.4 1.5 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain SNARE_assoc PF09335.6 EGG00727.1 - 9.2e-18 64.6 6.0 9.2e-18 64.6 4.1 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein ARL6IP6 PF15062.1 EGG00727.1 - 0.011 15.6 0.1 0.041 13.7 0.1 2.1 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix GILT PF03227.11 EGG00729.1 - 2.4e-09 36.9 0.7 2.4e-09 36.9 0.5 1.9 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_3 PF13192.1 EGG00729.1 - 0.097 12.5 0.2 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin domain Spt4 PF06093.8 EGG00730.1 - 7.9e-32 108.9 0.2 9.2e-32 108.7 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger GFA PF04828.9 EGG00730.1 - 0.036 14.0 0.2 0.05 13.5 0.2 1.3 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Peptidase_C74 PF12387.3 EGG00730.1 - 0.24 10.5 0.7 0.29 10.2 0.5 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase RNA_POL_M_15KD PF02150.11 EGG00730.1 - 0.28 10.8 3.4 0.85 9.3 1.2 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Peptidase_A22B PF04258.8 EGG00731.1 - 2e-80 270.4 5.3 2.4e-80 270.1 3.7 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EGG00731.1 - 0.0015 17.7 0.2 0.0015 17.7 0.2 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1119) Nucleoplasmin PF03066.10 EGG00731.1 - 0.19 11.2 6.2 5.6 6.4 2.7 2.2 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EGG00731.1 - 0.61 10.3 7.2 0.66 10.2 0.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4218 PF13960.1 EGG00733.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Syntaxin-6_N PF09177.6 EGG00734.1 - 0.032 14.6 0.1 4.9 7.6 0.0 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Sad1_UNC PF07738.8 EGG00735.1 - 1.3e-27 96.1 0.0 3.2e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal NADHdeh_related PF10125.4 EGG00735.1 - 0.027 13.6 0.1 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 NADH dehydrogenase I, subunit N related protein TPR_19 PF14559.1 EGG00738.1 - 1.5e-05 25.2 0.0 0.11 12.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.26 EGG00738.1 - 4.5e-05 23.0 0.0 0.00017 21.2 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_14 PF13428.1 EGG00738.1 - 0.00037 20.8 0.2 2.2 9.1 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EGG00738.1 - 0.0012 18.9 0.8 2.8 8.1 0.0 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGG00738.1 - 0.054 13.4 0.8 1.2 9.0 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Ecl1 PF12855.2 EGG00738.1 - 0.067 12.5 0.3 0.067 12.5 0.2 1.9 2 0 0 2 2 2 0 Life-span regulatory factor YL1 PF05764.8 EGG00739.1 - 5.9 6.4 6.6 0.18 11.3 0.6 1.4 2 0 0 2 2 2 0 YL1 nuclear protein DUF775 PF05603.7 EGG00741.1 - 1.9e-39 135.3 0.4 2.3e-39 135.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Utp14 PF04615.8 EGG00743.1 - 4.9e-140 468.0 48.5 6e-140 467.7 33.6 1.1 1 0 0 1 1 1 1 Utp14 protein Adeno_E3 PF06040.6 EGG00743.1 - 8.1 6.4 6.1 7.9 6.4 0.3 3.1 3 0 0 3 3 3 0 Adenovirus E3 protein DUF2894 PF11445.3 EGG00745.1 - 8.7 6.5 11.3 2 8.6 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) PAP2 PF01569.16 EGG00747.1 - 4.1e-19 68.5 3.7 4.1e-19 68.5 2.5 1.7 2 1 0 2 2 2 1 PAP2 superfamily TctB PF07331.6 EGG00747.1 - 0.31 10.7 4.9 0.13 11.8 1.1 2.0 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family KOW PF00467.24 EGG00748.1 - 5.5e-08 32.2 3.9 5.5e-08 32.2 2.7 2.4 3 0 0 3 3 3 1 KOW motif zf-rbx1 PF12678.2 EGG00751.1 - 4.7e-14 52.2 0.9 9.6e-14 51.2 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGG00751.1 - 1.3e-11 44.1 9.6 9.1e-11 41.4 6.7 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGG00751.1 - 4.4e-08 32.6 0.8 1.2e-07 31.2 0.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG00751.1 - 2.4e-06 27.4 2.6 2.4e-06 27.4 1.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG00751.1 - 5.1e-06 26.0 1.8 5.1e-06 26.0 1.3 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG00751.1 - 6.3e-06 25.8 2.1 2.3e-05 24.0 1.5 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGG00751.1 - 1.3e-05 24.7 1.8 9.6e-05 22.0 1.3 2.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EGG00751.1 - 0.0014 18.4 5.3 0.0048 16.7 3.7 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGG00751.1 - 0.0041 16.9 1.7 0.011 15.5 1.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EGG00751.1 - 0.19 11.6 2.9 0.65 10.0 2.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 EGG00751.1 - 0.21 11.1 2.0 0.46 10.0 1.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EGG00751.1 - 1.1 8.8 5.0 0.3 10.7 1.1 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RhoGEF PF00621.15 EGG00752.1 - 9.4e-25 87.5 0.0 1.4e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Glyco_transf_90 PF05686.7 EGG00753.1 - 2.2e-05 23.3 0.4 0.0009 18.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 Gln-synt_C PF00120.19 EGG00755.1 - 2.2e-35 122.0 0.0 9.9e-22 77.3 0.0 3.2 2 1 1 3 3 3 3 Glutamine synthetase, catalytic domain GATase_4 PF13230.1 EGG00755.1 - 0.054 12.1 0.0 0.091 11.4 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II IncA PF04156.9 EGG00758.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 IncA protein Ferritin_2 PF13668.1 EGG00761.1 - 7.9e-29 100.3 0.9 1.3e-28 99.6 0.7 1.3 1 1 0 1 1 1 1 Ferritin-like domain Csm1 PF12539.3 EGG00762.1 - 8.5e-06 26.1 0.0 1.9e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Ax_dynein_light PF10211.4 EGG00762.1 - 0.052 13.3 19.5 0.45 10.3 1.5 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain YodL PF14191.1 EGG00762.1 - 0.092 13.2 0.2 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 YodL-like Atg14 PF10186.4 EGG00762.1 - 0.16 10.9 27.4 0.94 8.3 2.2 2.5 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 EGG00762.1 - 0.32 10.1 6.4 0.38 9.8 3.3 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DASH_Dad3 PF08656.5 EGG00762.1 - 0.52 10.0 6.1 0.3 10.8 0.3 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 GAS PF13851.1 EGG00762.1 - 2.9 7.0 35.5 0.6 9.2 6.7 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding MRP-S26 PF14943.1 EGG00762.1 - 3.5 7.1 30.6 0.81 9.2 12.0 2.4 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 DUF2235 PF09994.4 EGG00763.1 - 6.9e-69 232.2 0.0 1.4e-68 231.2 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Fungal_trans PF04082.13 EGG00764.1 - 8.8e-19 67.3 0.9 1.9e-18 66.3 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGG00764.1 - 0.00022 21.0 9.7 0.00041 20.2 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADK PF00406.17 EGG00765.1 - 1.6e-49 167.6 0.0 2e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EGG00765.1 - 7.1e-12 45.7 0.0 1e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGG00765.1 - 4.9e-09 36.1 0.0 7.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EGG00765.1 - 3.4e-07 29.8 0.1 0.0045 16.3 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_17 PF13207.1 EGG00765.1 - 1.8e-06 28.7 0.0 2.5e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGG00765.1 - 0.0022 17.0 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin GFA PF04828.9 EGG00770.1 - 0.0033 17.3 0.6 0.24 11.3 0.2 2.6 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Porin_3 PF01459.17 EGG00772.1 - 1.7e-65 221.0 0.0 2e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF4131 PF13567.1 EGG00772.1 - 0.065 12.6 0.1 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) adh_short PF00106.20 EGG00774.1 - 1.9e-12 47.3 0.0 3.3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG00774.1 - 4.8e-05 23.2 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG00774.1 - 0.0049 16.5 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGG00774.1 - 0.03 13.7 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EGG00774.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Agouti PF05039.7 EGG00776.1 - 0.35 11.2 1.5 0.62 10.4 1.1 1.6 1 1 0 1 1 1 0 Agouti protein adh_short PF00106.20 EGG00778.1 - 1.6e-12 47.6 0.0 2.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG00778.1 - 6.7e-05 22.6 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGG00778.1 - 0.00095 19.2 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EGG00778.1 - 0.0042 16.8 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGG00778.1 - 0.007 15.8 0.0 0.0088 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGG00778.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GCOM2 PF15328.1 EGG00779.1 - 0.14 11.9 5.6 0.11 12.2 1.5 1.9 1 1 1 2 2 2 0 Putative GRINL1B complex locus protein 2 IL17_R_N PF15037.1 EGG00779.1 - 0.18 10.7 1.2 0.19 10.7 0.9 1.1 1 0 0 1 1 1 0 Interleukin-17 receptor extracellular region DUF3357 PF11837.3 EGG00779.1 - 6.4 6.6 8.5 0.59 10.0 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) LacI PF00356.16 EGG00780.1 - 0.015 14.9 0.2 0.031 13.9 0.2 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Baculo_PEP_C PF04513.7 EGG00782.1 - 0.011 15.5 1.9 0.076 12.8 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EGG00782.1 - 0.035 14.3 3.1 1.8 8.9 0.4 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein LPP PF04728.8 EGG00782.1 - 0.039 13.7 1.8 0.43 10.4 0.0 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Trans_reg_C PF00486.23 EGG00782.1 - 0.041 13.7 0.7 3 7.8 0.1 2.9 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal FlaC_arch PF05377.6 EGG00782.1 - 0.22 11.4 5.3 0.42 10.5 0.0 3.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EGG00782.1 - 0.38 10.3 11.9 0.57 9.7 5.4 2.4 2 0 0 2 2 2 0 IncA protein GAS PF13851.1 EGG00782.1 - 0.39 9.8 10.2 0.081 12.1 2.1 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EGG00782.1 - 0.5 9.4 2.0 0.49 9.5 0.3 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF1319 PF07028.6 EGG00782.1 - 0.65 10.2 9.5 1.6 8.9 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) DUF1978 PF09321.5 EGG00782.1 - 2 7.7 11.9 0.21 10.9 4.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) DUF4094 PF13334.1 EGG00782.1 - 4 7.8 10.5 0.82 10.0 0.1 3.7 3 2 2 5 5 5 0 Domain of unknown function (DUF4094) DUF2457 PF10446.4 EGG00784.1 - 2.7 6.6 10.4 2.7 6.5 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 EGG00784.1 - 4.7 6.3 6.2 5.5 6.1 4.3 1.2 1 0 0 1 1 1 0 NOA36 protein CPSF100_C PF13299.1 EGG00785.1 - 1.1e-09 38.6 0.0 1.7e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal eRF1_2 PF03464.10 EGG00785.1 - 0.0068 16.7 0.1 0.031 14.5 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 2 DUF1331 PF07048.6 EGG00787.1 - 1.1 8.7 3.4 2.5 7.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) DUF1744 PF08490.7 EGG00789.1 - 4e-110 368.1 0.8 5.6e-110 367.6 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EGG00789.1 - 1.7e-60 204.6 0.1 6.4e-59 199.4 0.1 2.4 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EGG00789.1 - 6.5e-19 68.0 0.0 1.1e-16 60.7 0.0 3.0 3 0 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EGG00789.1 - 6.8e-08 32.2 0.2 4e-07 29.7 0.1 2.2 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EGG00789.1 - 0.00015 21.6 0.0 0.00048 19.9 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily DUF4379 PF14311.1 EGG00789.1 - 0.018 14.8 0.2 0.049 13.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) DUF1654 PF07867.6 EGG00789.1 - 0.11 11.8 1.6 4.4 6.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) Sld5 PF05916.6 EGG00792.1 - 3.9e-13 49.6 0.1 8.6e-13 48.5 0.0 1.5 1 1 0 1 1 1 1 GINS complex protein Kin17_mid PF10357.4 EGG00793.1 - 3.6e-46 155.9 0.6 3.6e-46 155.9 0.4 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EGG00793.1 - 0.0014 18.7 2.5 0.0014 18.7 1.7 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGG00793.1 - 0.016 15.3 2.6 0.016 15.3 1.8 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGG00793.1 - 0.045 13.8 0.4 0.045 13.8 0.3 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) RyR PF02026.11 EGG00793.1 - 0.091 12.7 1.6 0.099 12.6 0.1 1.8 2 0 0 2 2 2 0 RyR domain DRY_EERY PF09750.4 EGG00793.1 - 0.89 9.6 7.1 1.3 9.1 4.7 1.5 1 1 0 1 1 1 0 Alternative splicing regulator Ecl1 PF12855.2 EGG00793.1 - 2 7.7 6.2 0.22 10.8 1.0 1.8 2 0 0 2 2 2 0 Life-span regulatory factor M157 PF11624.3 EGG00794.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 MHC class I-like protein M157 Peptidase_S64 PF08192.6 EGG00796.1 - 0.2 9.9 6.2 0.39 8.9 4.3 1.4 1 0 0 1 1 1 0 Peptidase family S64 DUF1264 PF06884.6 EGG00797.1 - 1.4e-38 131.9 0.5 1.8e-38 131.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Toxin_62 PF15540.1 EGG00801.1 - 0.058 13.5 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 62 Alpha_kinase PF02816.13 EGG00802.1 - 1.7e-07 31.1 0.1 7e-07 29.0 0.1 1.9 1 1 0 1 1 1 1 Alpha-kinase family Ribosomal_S24e PF01282.14 EGG00803.1 - 4.9e-33 112.7 0.0 8.6e-33 111.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e DUF4316 PF14195.1 EGG00803.1 - 1.6 8.8 4.8 5.1 7.2 3.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4316) ECH PF00378.15 EGG00804.1 - 4.9e-36 124.1 0.0 6.1e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family UBX PF00789.15 EGG00805.1 - 1.6e-14 53.6 0.0 6.1e-14 51.8 0.0 2.0 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EGG00805.1 - 7.7e-10 38.1 0.0 1.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EGG00805.1 - 0.00018 21.4 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like DUF2346 PF09803.4 EGG00809.1 - 3.8e-08 33.0 0.3 5.5e-08 32.5 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) VHS PF00790.14 EGG00811.1 - 7.5e-36 122.8 0.0 2e-35 121.4 0.0 1.8 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EGG00811.1 - 3.6e-21 75.0 0.3 9.4e-21 73.6 0.2 1.7 1 0 0 1 1 1 1 GAT domain Strep_SA_rep PF06696.6 EGG00811.1 - 0.75 9.6 4.3 0.27 11.0 0.2 2.3 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DUF2464 PF10240.4 EGG00811.1 - 0.78 9.0 3.5 1.4 8.1 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) Elong_Iki1 PF10483.4 EGG00813.1 - 0.14 11.5 3.5 1.5 8.0 0.4 2.1 2 0 0 2 2 2 0 Elongator subunit Iki1 LRR19-TM PF15176.1 EGG00814.1 - 0.24 11.1 1.5 0.59 9.8 1.1 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Hema_stalk PF08720.5 EGG00815.1 - 0.0015 18.0 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 Influenza C hemagglutinin stalk Mitochondr_Som1 PF11093.3 EGG00815.1 - 0.094 12.5 0.3 0.23 11.3 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial export protein Som1 DnaJ-X PF14308.1 EGG00816.1 - 0.0094 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing DUF1610 PF07754.6 EGG00818.1 - 0.23 11.6 1.9 0.33 11.0 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) DUF3819 PF12842.2 EGG00819.1 - 1.1e-05 25.1 0.0 1.6e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) PBP_sp32 PF07222.7 EGG00821.1 - 0.052 12.7 0.4 0.081 12.0 0.3 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pmp3 PF01679.12 EGG00822.1 - 1.2e-22 79.3 5.4 1.3e-22 79.1 3.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1056 PF06341.6 EGG00822.1 - 0.011 15.7 0.2 0.013 15.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) Arabinose_trans PF04602.7 EGG00822.1 - 0.099 10.8 0.4 0.097 10.8 0.3 1.0 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein CorA PF01544.13 EGG00823.1 - 0.61 9.0 2.8 1.4 7.8 2.0 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Pmp3 PF01679.12 EGG00824.1 - 3.8e-17 61.7 8.5 4.7e-17 61.4 5.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator LPAM_2 PF13627.1 EGG00824.1 - 0.92 9.2 3.7 2.4 7.9 2.5 1.8 1 1 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Synaptobrevin PF00957.16 EGG00825.1 - 1.7e-30 104.4 0.1 2e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Synaptobrevin PsbI PF02532.9 EGG00825.1 - 0.87 9.2 3.1 1.1 8.8 2.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Nodulin_late PF07127.6 EGG00827.1 - 2 8.6 10.0 0.3 11.2 0.8 2.9 2 2 1 3 3 3 0 Late nodulin protein F-box PF00646.28 EGG00828.1 - 0.0025 17.3 1.0 0.15 11.7 0.0 3.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EGG00828.1 - 0.033 13.8 0.0 0.12 12.1 0.0 2.0 1 1 0 1 1 1 0 F-box-like Pico_P1A PF02226.11 EGG00828.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) Ndc1_Nup PF09531.5 EGG00829.1 - 3.2 6.0 9.0 3.4 5.9 6.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Abhydrolase_6 PF12697.2 EGG00830.1 - 8.7e-16 58.4 0.0 1.6e-15 57.5 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG00830.1 - 2.7e-13 49.9 0.0 4.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGG00830.1 - 6.3e-05 22.7 0.1 0.00012 21.8 0.1 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 EGG00830.1 - 0.013 14.9 0.2 0.032 13.6 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.16 EGG00830.1 - 0.037 13.2 0.0 2.7 7.1 0.0 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EGG00830.1 - 0.063 12.8 0.1 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EGG00831.1 - 9.4e-09 35.1 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGG00831.1 - 7.6e-08 32.5 0.0 8.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EGG00831.1 - 2.2e-05 23.8 0.0 5.9e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EGG00831.1 - 9.9e-05 22.1 0.0 0.00013 21.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG00831.1 - 0.00059 19.4 0.0 0.00067 19.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 EGG00831.1 - 0.0043 16.0 0.0 0.0062 15.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 EGG00831.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 EGG00831.1 - 0.013 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 EGG00831.1 - 0.035 13.5 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase MBOAT_2 PF13813.1 EGG00833.1 - 5.5e-16 58.4 0.1 2.2e-15 56.4 0.1 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Bac_surface_Ag PF01103.18 EGG00834.1 - 1.3e-38 133.3 0.9 3.5e-38 131.8 0.2 1.8 1 1 1 2 2 2 1 Surface antigen RabGAP-TBC PF00566.13 EGG00835.1 - 3.2e-26 92.1 0.1 6.4e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pyridoxal_deC PF00282.14 EGG00836.1 - 2.8e-59 200.4 0.0 4.1e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGG00836.1 - 0.0024 16.6 0.0 0.0042 15.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DNA_mis_repair PF01119.14 EGG00837.1 - 1.6e-27 95.3 0.0 2.9e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EGG00837.1 - 2.8e-15 56.1 0.0 6.5e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGG00837.1 - 1.9e-11 43.6 0.0 4.2e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BioT2 PF15368.1 EGG00837.1 - 0.016 14.9 0.1 2.4 7.8 0.0 2.8 2 0 0 2 2 2 0 Spermatogenesis family BioT2 HD_assoc PF13286.1 EGG00837.1 - 0.029 14.6 0.2 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Phosphohydrolase-associated domain Bestrophin PF01062.16 EGG00840.1 - 8.2e-47 159.5 0.9 7.9e-28 97.2 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel FUSC PF04632.7 EGG00840.1 - 0.13 10.6 2.6 0.058 11.8 0.2 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family Bestrophin PF01062.16 EGG00843.1 - 5.4e-47 160.1 0.6 1e-28 100.1 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.16 EGG00844.1 - 8.9e-27 93.7 1.7 1.2e-26 93.3 1.2 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Alpha_kinase PF02816.13 EGG00845.1 - 8.2e-24 84.3 0.1 9.8e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family FlhD PF05247.8 EGG00845.1 - 0.056 13.4 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhD) Bestrophin PF01062.16 EGG00846.1 - 3.3e-37 128.0 2.4 5.9e-25 87.8 2.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel EFG_C PF00679.19 EGG00849.1 - 1e-07 31.6 0.0 1.1e-07 31.6 0.0 1.0 1 0 0 1 1 1 1 Elongation factor G C-terminus Nop10p PF04135.7 EGG00851.1 - 2e-22 78.6 0.1 2.4e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family GCM PF03615.10 EGG00853.1 - 8.5e-05 22.1 2.9 0.00012 21.6 0.6 2.2 2 0 0 2 2 2 1 GCM motif protein Mif2_N PF15624.1 EGG00853.1 - 2.4 8.7 11.1 0.16 12.5 3.6 2.0 2 1 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal rRNA_proc-arch PF13234.1 EGG00855.1 - 9.1e-88 293.8 0.2 1.6e-87 293.0 0.0 1.5 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 EGG00855.1 - 3.1e-58 195.9 0.4 6.2e-58 195.0 0.3 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EGG00855.1 - 8.1e-22 77.4 0.0 2.2e-21 76.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG00855.1 - 1.4e-07 31.2 0.0 3.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGG00855.1 - 0.0014 18.7 0.0 3.7 7.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 EGG00855.1 - 0.027 13.3 0.0 0.059 12.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EGG00855.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Acetyltransf_7 PF13508.1 EGG00856.1 - 7.4e-08 32.4 0.0 9.9e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGG00856.1 - 4.1e-07 29.9 0.0 5.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EGG00856.1 - 0.00026 20.8 0.0 0.00065 19.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain HK PF02110.10 EGG00856.1 - 0.029 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Acetyltransf_10 PF13673.1 EGG00856.1 - 0.037 14.1 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Adaptin_binding PF10199.4 EGG00858.1 - 1.6e-05 25.1 2.8 1.6e-05 25.1 2.0 2.3 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 PC_rep PF01851.17 EGG00859.1 - 2.5e-21 74.6 18.1 0.00031 20.8 0.0 9.2 10 0 0 10 10 10 6 Proteasome/cyclosome repeat RHD3 PF05879.7 EGG00861.1 - 1e-36 126.1 0.7 1.1e-23 83.1 0.0 2.1 2 0 0 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 EGG00861.1 - 0.0059 16.4 0.5 0.011 15.5 0.2 1.5 1 1 0 1 1 1 1 Dynamin family Miro PF08477.8 EGG00861.1 - 0.022 15.2 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 EGG00861.1 - 0.024 14.6 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EGG00861.1 - 0.041 13.8 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain GATase_7 PF13537.1 EGG00861.1 - 0.081 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain MFS_1 PF07690.11 EGG00863.1 - 1.6e-30 105.9 25.5 2e-30 105.7 17.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EGG00864.1 - 5.1e-21 74.7 31.4 1.8e-20 72.9 21.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF572 PF04502.8 EGG00870.1 - 4.8 6.3 23.5 15 4.6 16.5 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF572) Gly-rich_Ago1 PF12764.2 EGG00871.1 - 0.65 10.6 3.7 0.56 10.8 0.9 1.9 1 1 1 2 2 2 0 Glycine-rich region of argonaut Peptidase_C50 PF03568.12 EGG00872.1 - 0.021 13.5 3.5 0.015 13.9 0.7 1.9 1 1 1 2 2 2 0 Peptidase family C50 Tox-SHH PF15652.1 EGG00872.1 - 0.53 10.9 3.3 0.29 11.7 0.6 1.8 2 0 0 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature DUF812 PF05667.6 EGG00879.1 - 0.24 9.8 0.0 0.39 9.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GLE1 PF07817.8 EGG00882.1 - 0.0051 15.7 0.2 0.11 11.4 0.0 2.2 2 0 0 2 2 2 2 GLE1-like protein Vip3A_N PF12495.3 EGG00882.1 - 0.076 12.6 0.3 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal DUF2477 PF10631.4 EGG00883.1 - 0.059 13.5 5.4 0.31 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) DEAD_assoc PF08494.6 EGG00883.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 DEAD/H associated zf-CCHC PF00098.18 EGG00883.1 - 0.41 10.6 2.9 0.22 11.5 0.6 1.7 2 0 0 2 2 2 0 Zinc knuckle Ran_BP1 PF00638.13 EGG00885.1 - 1.8e-09 37.6 0.7 4.8e-09 36.3 0.5 1.7 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 EGG00885.1 - 1.1e-07 32.1 0.2 1.1e-07 32.1 0.1 4.9 6 0 0 6 6 6 1 NUP50 (Nucleoporin 50 kDa) Nucleoporin_FG PF13634.1 EGG00885.1 - 0.01 16.0 36.2 0.01 16.0 25.1 6.0 2 2 0 2 2 2 0 Nucleoporin FG repeat region MAM33 PF02330.11 EGG00885.1 - 0.15 11.7 0.6 3.1 7.4 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial glycoprotein Peptidase_M50B PF13398.1 EGG00893.1 - 5.7e-54 182.5 14.4 7.4e-54 182.1 10.0 1.1 1 0 0 1 1 1 1 Peptidase M50B-like DUF4040 PF13244.1 EGG00893.1 - 0.015 15.2 1.1 0.015 15.2 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4040) DUF373 PF04123.8 EGG00893.1 - 1.5 7.7 4.7 0.87 8.5 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) GTP1_OBG PF01018.17 EGG00895.1 - 2.2e-37 128.1 6.8 2.9e-37 127.7 4.7 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 EGG00895.1 - 1.1e-16 60.8 0.0 2e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGG00895.1 - 1.4e-05 24.4 0.0 5.3e-05 22.5 0.0 2.0 2 1 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EGG00895.1 - 0.00024 21.5 0.0 0.00067 20.1 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG00895.1 - 0.00081 18.6 0.2 0.27 10.4 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family MobB PF03205.9 EGG00895.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EGG00895.1 - 0.034 13.6 0.0 0.57 9.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EGG00895.1 - 0.047 12.4 0.0 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 EGG00895.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter LRR_4 PF12799.2 EGG00896.1 - 1.4e-05 24.6 0.6 0.0012 18.4 0.1 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EGG00896.1 - 0.012 15.3 0.3 0.24 11.1 0.0 2.4 2 0 0 2 2 2 0 F-box-like LRR_8 PF13855.1 EGG00896.1 - 0.022 14.5 2.2 0.32 10.7 0.3 2.8 1 1 2 3 3 3 0 Leucine rich repeat 2-Hacid_dh_C PF02826.14 EGG00899.1 - 3e-51 173.0 0.0 4.3e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGG00899.1 - 2.4e-16 59.3 0.0 2.9e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGG00899.1 - 0.00096 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase LRR_6 PF13516.1 EGG00900.1 - 4e-10 38.7 17.5 0.013 15.5 1.0 6.9 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.2 EGG00900.1 - 3.6e-09 36.0 21.7 0.00013 21.5 2.4 3.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGG00900.1 - 0.00011 21.6 15.6 0.57 10.4 0.8 6.8 5 1 2 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 EGG00900.1 - 0.00035 20.2 16.7 0.086 12.6 4.3 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 EGG00900.1 - 0.00069 19.4 13.1 11 6.7 0.0 6.9 5 1 1 6 6 6 1 Leucine rich repeat adh_short PF00106.20 EGG00901.1 - 4.6e-19 68.9 0.1 1.5e-18 67.2 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG00901.1 - 1.3e-16 61.1 0.0 1.7e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG00901.1 - 8.3e-05 22.3 0.1 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Zip PF02535.17 EGG00902.1 - 1.8e-49 168.4 7.7 2.1e-49 168.2 5.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Metallophos PF00149.23 EGG00904.1 - 6.8e-44 149.6 0.1 8.5e-44 149.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HeLo PF14479.1 EGG00906.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation Glyco_hydro_85 PF03644.8 EGG00909.1 - 6.7e-18 64.8 0.1 1.1e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Acetyltransf_1 PF00583.19 EGG00911.1 - 5e-12 45.6 0.0 7.1e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGG00911.1 - 2.1e-11 43.8 0.0 3e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGG00911.1 - 0.0047 16.6 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGG00911.1 - 0.014 15.4 0.0 0.023 14.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGG00911.1 - 0.055 13.3 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PX PF00787.19 EGG00912.1 - 5.9e-19 67.9 0.1 2.1e-18 66.1 0.0 2.0 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 EGG00912.1 - 0.0014 17.9 1.6 0.015 14.5 1.0 2.5 2 1 1 3 3 3 1 WASP-binding domain of Sorting nexin protein WXG100 PF06013.7 EGG00912.1 - 0.045 13.7 0.4 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Myb_DNA-binding PF00249.26 EGG00914.1 - 7.8e-20 70.6 2.4 4.9e-10 39.3 0.1 4.1 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGG00914.1 - 2.6e-15 56.2 7.0 1.1e-11 44.6 0.4 4.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Cupin_2 PF07883.6 EGG00915.1 - 7.4e-21 73.4 0.3 1.3e-11 43.7 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 EGG00915.1 - 1.8e-18 66.3 0.0 5e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 EGG00915.1 - 0.00011 21.5 0.0 0.061 12.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 EGG00915.1 - 0.0011 18.6 0.0 0.77 9.3 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase DUF1431 PF07248.7 EGG00917.1 - 0.0059 16.6 0.3 0.0084 16.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1431) ACBP PF00887.14 EGG00918.1 - 5.3e-29 99.7 0.1 6.6e-29 99.4 0.1 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Tox-REase-5 PF15648.1 EGG00918.1 - 0.0016 18.6 0.9 0.0022 18.2 0.5 1.3 1 1 0 1 1 1 1 Restriction endonuclease fold toxin 5 Caudo_TAP PF02413.12 EGG00918.1 - 0.031 14.4 0.4 0.036 14.2 0.3 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein NIF PF03031.13 EGG00919.1 - 1e-08 35.0 4.3 0.0075 15.9 0.1 4.0 2 2 1 3 3 3 2 NLI interacting factor-like phosphatase Sterile PF03015.14 EGG00919.1 - 0.013 15.7 0.1 2.3 8.5 0.0 2.9 1 1 1 2 2 2 0 Male sterility protein Glyco_transf_8C PF08437.5 EGG00919.1 - 0.024 14.6 1.0 7.1 6.7 0.0 2.7 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal DUF3140 PF11338.3 EGG00919.1 - 0.031 14.3 1.8 0.58 10.3 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3140) DUF2718 PF10918.3 EGG00919.1 - 0.055 13.5 0.2 0.055 13.5 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2718) Syntaxin-6_N PF09177.6 EGG00920.1 - 1.5e-07 31.6 0.3 4.6e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EGG00920.1 - 0.019 14.6 1.2 0.04 13.6 0.3 2.0 2 0 0 2 2 2 0 SNARE domain ANAPC15 PF15243.1 EGG00920.1 - 0.1 12.6 2.9 0.16 12.0 2.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF1900 PF08954.6 EGG00921.1 - 8.6e-57 190.4 0.4 1.9e-27 95.4 0.0 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF1900) PQQ_3 PF13570.1 EGG00921.1 - 0.16 12.2 0.0 7 7.0 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain WD40 PF00400.27 EGG00921.1 - 0.41 10.6 22.8 0.043 13.7 0.7 6.6 8 0 0 8 8 8 0 WD domain, G-beta repeat Cyt-b5 PF00173.23 EGG00923.1 - 7.3e-12 44.9 0.0 8.9e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ADH_N PF08240.7 EGG00924.1 - 3.7e-22 78.1 0.2 6.2e-22 77.4 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGG00924.1 - 1e-15 57.3 0.0 1.5e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 EGG00924.1 - 0.0088 15.8 0.2 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 ThiF family Spermine_synth PF01564.12 EGG00924.1 - 0.022 13.6 0.0 0.059 12.3 0.0 1.6 2 0 0 2 2 2 0 Spermine/spermidine synthase Med26 PF08711.6 EGG00925.1 - 1e-11 44.1 0.5 2.4e-11 42.9 0.1 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain ScpA_ScpB PF02616.9 EGG00925.1 - 0.39 10.2 5.3 0.65 9.5 3.7 1.3 1 0 0 1 1 1 0 ScpA/B protein Bromo_TP PF07524.8 EGG00926.1 - 0.00042 19.9 0.0 0.00079 19.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 EGG00926.1 - 0.012 15.6 8.0 0.041 13.9 2.6 2.6 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term Gag_spuma PF03276.9 EGG00926.1 - 0.014 13.7 2.9 0.02 13.2 2.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein RabGAP-TBC PF00566.13 EGG00927.1 - 9.1e-37 126.6 1.4 1.1e-36 126.3 1.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 4HBT PF03061.17 EGG00928.1 - 1.1e-07 31.8 0.0 3e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily M20_dimer PF07687.9 EGG00930.1 - 4e-11 42.6 0.0 7.1e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EGG00930.1 - 1.8e-07 30.8 0.1 2.6e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Dus PF01207.12 EGG00933.1 - 1.5e-37 129.0 0.0 1.1e-36 126.2 0.0 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EGG00933.1 - 1.3e-05 24.6 0.0 2.7e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.16 EGG00933.1 - 0.00024 20.1 0.0 0.33 9.8 0.0 2.2 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase IMPDH PF00478.20 EGG00933.1 - 0.02 13.8 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGG00933.1 - 0.036 12.9 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase IGPS PF00218.16 EGG00933.1 - 0.044 12.8 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.12 EGG00933.1 - 0.11 11.5 0.0 0.26 10.3 0.0 1.6 1 1 0 1 1 1 0 Thiamine monophosphate synthase/TENI EMP24_GP25L PF01105.19 EGG00937.1 - 8.9e-42 142.8 0.1 1e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kelch_5 PF13854.1 EGG00938.1 - 9.7e-13 47.7 8.6 5.8e-10 38.9 0.2 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EGG00938.1 - 5.2e-11 42.3 13.9 1.6e-05 24.9 0.0 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EGG00938.1 - 3e-05 24.0 10.6 4.5 7.6 0.0 6.5 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.1 EGG00938.1 - 3.6e-05 23.4 12.7 5.6 6.8 0.1 6.6 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EGG00938.1 - 0.0047 16.6 12.2 0.057 13.1 0.4 5.4 5 1 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 EGG00938.1 - 0.0084 15.6 5.9 0.22 11.0 0.1 4.7 4 1 0 4 4 4 1 Kelch motif Amnionless PF14828.1 EGG00938.1 - 0.049 12.1 0.1 0.14 10.6 0.0 1.6 2 0 0 2 2 2 0 Amnionless Syndecan PF01034.15 EGG00938.1 - 0.17 11.5 0.1 0.38 10.4 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain TPR_16 PF13432.1 EGG00939.1 - 1.1e-08 35.4 0.1 0.00038 21.0 0.2 2.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGG00939.1 - 2.4e-08 33.5 2.1 1.2e-05 24.8 0.3 2.9 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.1 EGG00939.1 - 5.8e-08 32.6 0.3 0.0011 19.4 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGG00939.1 - 3.1e-06 26.6 7.0 0.0025 17.5 0.0 4.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGG00939.1 - 3.4e-06 27.3 3.0 0.00054 20.2 0.1 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGG00939.1 - 9.3e-06 25.4 0.1 0.36 11.1 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGG00939.1 - 2.6e-05 23.6 4.0 0.0056 16.3 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGG00939.1 - 3.8e-05 22.8 0.1 7.7e-05 21.8 0.1 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGG00939.1 - 4.6e-05 22.8 2.1 0.29 11.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGG00939.1 - 9.9e-05 21.7 2.4 0.027 14.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGG00939.1 - 0.00064 19.6 6.0 0.0062 16.4 1.6 3.0 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGG00939.1 - 0.00075 19.8 2.4 1.6 9.3 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat USP8_dimer PF08969.6 EGG00939.1 - 0.0034 17.3 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 USP8 dimerisation domain Apc3 PF12895.2 EGG00939.1 - 0.0045 17.0 4.6 0.027 14.6 0.6 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGG00939.1 - 0.047 13.5 0.4 0.1 12.4 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HECT_2 PF09814.4 EGG00940.1 - 1.3e-13 50.4 0.1 4.3e-13 48.7 0.0 1.7 1 1 0 2 2 2 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Nucleoporin_FG PF13634.1 EGG00940.1 - 0.00034 20.8 2.0 0.00056 20.1 1.4 1.2 1 0 0 1 1 1 1 Nucleoporin FG repeat region PITH PF06201.8 EGG00941.1 - 1.2e-37 129.0 0.0 1.4e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain DUF2296 PF10058.4 EGG00942.1 - 2.1e-20 72.1 0.2 3.5e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Mu-like_Com PF10122.4 EGG00942.1 - 0.0045 15.9 0.2 0.011 14.7 0.1 1.6 1 0 0 1 1 1 1 Mu-like prophage protein Com DUF3813 PF12758.2 EGG00942.1 - 0.097 12.8 1.9 0.28 11.3 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) TMF_DNA_bd PF12329.3 EGG00942.1 - 0.91 9.3 14.9 3.3 7.5 0.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3573 PF12097.3 EGG00942.1 - 4.7 5.7 5.0 2.3 6.7 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) PLAC8 PF04749.12 EGG00943.1 - 5.7e-17 62.2 5.9 7.6e-17 61.8 4.1 1.2 1 0 0 1 1 1 1 PLAC8 family UCH PF00443.24 EGG00944.1 - 2.6e-89 298.9 0.4 2.2e-44 151.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGG00944.1 - 2.2e-41 142.2 1.5 2.8e-20 72.9 0.0 2.9 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EGG00944.1 - 1.6e-06 27.6 10.4 0.0023 17.2 1.1 4.3 2 2 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase CpXC PF14353.1 EGG00944.1 - 0.047 13.6 1.2 11 5.9 0.0 3.8 4 0 0 4 4 4 0 CpXC protein Rep_fac-A_C PF08646.5 EGG00944.1 - 0.27 10.9 1.6 7.8 6.1 0.0 2.8 2 1 0 2 2 2 0 Replication factor-A C terminal domain E6 PF00518.12 EGG00944.1 - 0.53 10.6 6.8 12 6.3 0.1 3.5 4 0 0 4 4 4 0 Early Protein (E6) DNA_pol_A PF00476.15 EGG00945.1 - 2.5e-95 319.3 0.0 5.6e-95 318.1 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family A zf-C2H2_jaz PF12171.3 EGG00946.1 - 9.7e-06 25.5 0.1 1.9e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Calpain_inhib PF00748.14 EGG00946.1 - 0.005 17.1 1.2 0.005 17.1 0.9 2.6 2 1 1 3 3 3 1 Calpain inhibitor zf-met PF12874.2 EGG00946.1 - 0.058 13.6 0.2 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGG00947.1 - 4.2e-05 23.5 0.1 8.4e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Calpain_inhib PF00748.14 EGG00947.1 - 0.0031 17.8 1.0 0.0031 17.8 0.7 2.6 2 1 1 3 3 3 1 Calpain inhibitor zf-met PF12874.2 EGG00947.1 - 0.082 13.1 0.4 0.18 12.0 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Polysacc_deac_1 PF01522.16 EGG00948.1 - 4.1e-17 61.9 0.0 6.3e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Mucin PF01456.12 EGG00948.1 - 0.064 13.0 8.6 0.14 11.9 6.0 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein PH_9 PF15410.1 EGG00949.1 - 2.3e-05 24.5 0.0 7.4e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain BCL_N PF04714.8 EGG00949.1 - 0.1 12.1 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 BCL7, N-terminal conserver region Brix PF04427.13 EGG00951.1 - 6.1e-30 104.3 0.2 1.2e-28 100.0 0.1 2.1 1 1 0 1 1 1 1 Brix domain A_deaminase PF00962.17 EGG00953.1 - 1.4e-101 339.7 0.0 4.1e-101 338.1 0.0 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase SSP160 PF06933.6 EGG00954.1 - 0.053 11.4 15.7 0.15 10.0 10.9 1.7 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Nup96 PF12110.3 EGG00956.1 - 2e-78 263.4 0.1 2.8e-78 262.9 0.1 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EGG00956.1 - 2.1e-47 160.4 0.0 4.2e-47 159.5 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EGG00956.1 - 1.9e-28 98.9 317.0 6.1e-11 42.5 32.1 10.0 3 1 5 8 8 8 4 Nucleoporin FG repeat region MtrF PF09472.5 EGG00958.1 - 0.13 11.5 0.7 0.21 10.8 0.5 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) RCR PF12273.3 EGG00958.1 - 3.9 8.0 16.6 16 6.0 11.5 2.1 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red CytochromB561_N PF09786.4 EGG00959.1 - 0.81 8.0 4.6 1.1 7.6 3.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SAM_2 PF07647.12 EGG00962.1 - 1.2e-08 34.6 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGG00962.1 - 4.2e-06 26.8 0.0 9.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Glyco_hydro_18 PF00704.23 EGG00963.1 - 9.1e-57 193.0 0.7 1.4e-56 192.4 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SUN PF03856.8 EGG00963.1 - 0.0034 16.7 0.0 0.0058 15.9 0.0 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Glyco_hydro_85 PF03644.8 EGG00963.1 - 0.0038 16.4 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Pacifastin_I PF05375.8 EGG00966.1 - 0.74 9.3 6.2 0.45 10.0 0.6 2.6 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) Pacifastin_I PF05375.8 EGG00967.1 - 3 7.4 7.6 0.79 9.2 1.4 2.4 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) ATG11 PF10377.4 EGG00969.1 - 9e-30 103.2 0.0 9e-30 103.2 0.0 3.1 3 0 0 3 3 3 1 Autophagy-related protein 11 APG17 PF04108.7 EGG00969.1 - 5.2e-07 28.8 0.7 5.2e-07 28.8 0.5 3.5 2 1 1 3 3 3 1 Autophagy protein Apg17 WD40_alt PF14077.1 EGG00969.1 - 0.69 9.5 7.4 13 5.4 0.3 3.6 3 0 0 3 3 3 0 Alternative WD40 repeat motif ERM PF00769.14 EGG00969.1 - 3.8 6.9 52.3 0.43 10.0 21.4 2.8 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Lipid_bd PF12888.2 EGG00971.1 - 0.28 11.0 2.9 24 4.7 0.1 4.0 1 1 3 5 5 5 0 Lipid-binding putative hydrolase 7TMR-DISMED2 PF07696.6 EGG00971.1 - 0.33 10.3 8.4 2 7.8 0.2 4.2 1 1 2 5 5 5 0 7TMR-DISM extracellular 2 DNA_pol3_chi PF04364.8 EGG00971.1 - 0.93 9.3 2.5 36 4.1 0.1 3.4 3 2 0 3 3 3 0 DNA polymerase III chi subunit, HolC Serpulina_VSP PF05540.6 EGG00972.1 - 0.037 12.8 0.0 0.05 12.3 0.0 1.1 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein Secretin_N_2 PF07655.8 EGG00972.1 - 2.9 8.3 11.5 0.9 9.9 5.0 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Met_10 PF02475.11 EGG00974.1 - 2.2e-55 187.3 0.0 3.5e-55 186.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EGG00974.1 - 6.3e-06 26.2 0.0 2.1e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TRM PF02005.11 EGG00974.1 - 7.1e-06 25.1 0.0 1.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.9 EGG00974.1 - 0.00022 20.6 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EGG00974.1 - 0.00042 19.8 0.0 0.00078 19.0 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 EGG00974.1 - 0.00044 19.4 0.0 0.0008 18.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 EGG00974.1 - 0.02 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EGG00974.1 - 0.023 15.2 0.0 0.05 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EGG00974.1 - 0.097 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ADH_zinc_N PF00107.21 EGG00974.1 - 0.22 11.1 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UBN2 PF14223.1 EGG00976.1 - 0.015 15.0 0.1 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG00976.1 - 0.048 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type QRPTase_C PF01729.14 EGG00977.1 - 1.6e-55 187.2 0.0 1.9e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EGG00977.1 - 4.1e-21 74.5 0.0 1e-20 73.3 0.0 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain TMP-TENI PF02581.12 EGG00977.1 - 0.0066 15.5 0.0 0.017 14.2 0.0 1.6 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI DHQS PF01959.11 EGG00977.1 - 0.043 12.5 0.2 0.099 11.3 0.0 1.6 2 0 0 2 2 2 0 3-dehydroquinate synthase (EC 4.6.1.3) Ribul_P_3_epim PF00834.14 EGG00977.1 - 0.053 12.6 0.0 0.11 11.5 0.0 1.6 1 1 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Alginate_lyase PF05426.7 EGG00978.1 - 0.032 13.5 0.1 0.034 13.5 0.1 1.1 1 0 0 1 1 1 0 Alginate lyase PAC2 PF09754.4 EGG00978.1 - 0.035 13.9 0.1 0.052 13.3 0.0 1.3 1 1 0 1 1 1 0 PAC2 family DUF3287 PF11690.3 EGG00978.1 - 0.18 11.9 1.0 0.28 11.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF221 PF02714.10 EGG00979.1 - 4.9e-98 327.9 23.4 7.7e-98 327.3 16.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGG00979.1 - 7e-43 145.8 0.9 2.3e-42 144.2 0.6 2.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGG00979.1 - 5.9e-16 58.7 0.0 1e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 EGG00979.1 - 1.2e-11 44.3 0.2 7.8e-11 41.7 0.0 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein HAD PF12710.2 EGG00980.1 - 1.6e-18 67.5 0.0 2.1e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGG00980.1 - 1.9e-07 31.4 0.0 1.9e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EGG00980.1 - 0.00014 21.1 0.1 0.00043 19.5 0.0 1.7 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.21 EGG00980.1 - 0.00027 21.4 0.0 0.033 14.6 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EGG00980.1 - 0.0034 16.7 0.0 0.0073 15.6 0.0 1.8 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) LNS2 PF08235.8 EGG00980.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lactamase_B_2 PF12706.2 EGG00980.1 - 0.044 13.3 0.0 0.066 12.7 0.0 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Ins_allergen_rp PF06757.8 EGG00980.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Methyltransf_16 PF10294.4 EGG00981.1 - 2.4e-09 36.8 0.0 3e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGG00981.1 - 0.0012 19.3 0.0 0.0016 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG00981.1 - 0.12 11.6 0.0 0.2 11.0 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase small domain FRQ PF09421.5 EGG00982.1 - 0.24 9.1 4.3 0.18 9.5 1.4 1.7 1 1 1 2 2 2 0 Frequency clock protein RAI1 PF08652.6 EGG00986.1 - 0.033 13.9 3.9 1.1 9.0 0.0 2.9 2 1 1 3 3 3 0 RAI1 like PD-(D/E)XK nuclease Zn_clus PF00172.13 EGG00988.1 - 6.7e-08 32.3 9.4 1.1e-07 31.6 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EGG00989.1 - 6.3e-29 101.0 0.0 9.9e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG00989.1 - 6.8e-24 84.9 0.1 8.5e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG00989.1 - 6.2e-09 35.7 0.0 8.8e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGG00989.1 - 0.013 14.9 0.1 0.048 13.0 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGG00989.1 - 0.029 14.1 0.4 0.053 13.3 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4179 PF13786.1 EGG00989.1 - 1.8 8.8 5.4 3.9 7.7 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4179) COPR5 PF15340.1 EGG00990.1 - 0.0019 18.5 0.1 0.0032 17.8 0.1 1.3 1 0 0 1 1 1 1 Cooperator of PRMT5 family TatD_DNase PF01026.16 EGG00991.1 - 0.059 12.5 0.0 0.059 12.5 0.0 1.0 1 0 0 1 1 1 0 TatD related DNase DUF2321 PF10083.4 EGG00991.1 - 0.1 12.0 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DBD_Tnp_Mut PF03108.10 EGG00992.1 - 0.029 13.9 0.0 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 MuDR family transposase AFT PF08731.6 EGG00992.1 - 0.095 12.8 0.0 0.095 12.8 0.0 3.3 2 1 0 2 2 2 0 Transcription factor AFT zf-CCHC PF00098.18 EGG00994.1 - 0.02 14.8 3.8 0.033 14.1 2.6 1.4 1 0 0 1 1 1 0 Zinc knuckle CLP_protease PF00574.18 EGG00996.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Clp protease HisKA_2 PF07568.7 EGG00997.1 - 0.03 14.1 0.1 0.074 12.9 0.1 1.7 1 1 0 1 1 1 0 Histidine kinase Picorna_P3A PF06363.6 EGG01006.1 - 0.54 10.2 2.0 0.47 10.4 0.2 1.7 2 0 0 2 2 2 0 Picornaviridae P3A protein SCIMP PF15050.1 EGG01006.1 - 7 6.5 7.1 0.41 10.5 0.2 2.3 2 1 1 3 3 3 0 SCIMP protein CCT PF06203.9 EGG01007.1 - 0.82 9.3 4.2 0.51 10.0 1.8 1.5 2 0 0 2 2 2 0 CCT motif Gly_transf_sug PF04488.10 EGG01008.1 - 1.8e-12 47.5 0.0 4.8e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif OTU PF02338.14 EGG01011.1 - 0.0036 17.8 0.0 0.0079 16.7 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Endotoxin_N PF03945.9 EGG01011.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Arginase PF00491.16 EGG01015.1 - 2e-74 250.4 0.0 2.3e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family PASTA PF03793.14 EGG01017.1 - 0.0039 16.8 0.1 0.0084 15.7 0.1 1.6 1 0 0 1 1 1 1 PASTA domain V-set PF07686.12 EGG01017.1 - 0.057 13.3 0.1 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin V-set domain V-set PF07686.12 EGG01019.1 - 0.13 12.1 0.2 0.76 9.6 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin V-set domain DUF2457 PF10446.4 EGG01020.1 - 0.16 10.6 2.7 0.29 9.7 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Haem_oxygenas_2 PF14518.1 EGG01024.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Iron-containing redox enzyme MFS_1 PF07690.11 EGG01025.1 - 6.6e-23 80.9 31.4 1.9e-22 79.4 21.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UbiA PF01040.13 EGG01026.1 - 0.004 16.4 0.1 0.0041 16.3 0.1 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Cpn10 PF00166.16 EGG01028.1 - 5.5e-28 96.7 0.0 6.1e-28 96.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Trehalose_PPase PF02358.11 EGG01029.1 - 6.8e-21 74.2 0.3 1e-20 73.6 0.2 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EGG01029.1 - 1.2e-11 44.7 0.1 3.3e-08 33.4 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 EGG01030.1 - 1.6e-19 69.7 0.0 1.6e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.7 EGG01030.1 - 1.5e-11 44.3 0.0 4.2e-09 36.3 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EGG01030.1 - 4.4e-09 35.9 0.0 7.7e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Sel1 PF08238.7 EGG01030.1 - 0.16 12.6 1.3 4 8.2 0.1 2.6 2 0 0 2 2 2 0 Sel1 repeat M PF02370.11 EGG01033.1 - 4.8 7.8 6.3 5.6 7.6 0.4 3.3 3 0 0 3 3 3 0 M protein repeat Pentaxin PF00354.12 EGG01036.1 - 0.083 12.3 0.1 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Pentaxin family RTC4 PF14474.1 EGG01037.1 - 6.3e-13 48.7 0.0 1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain DUF4643 PF15485.1 EGG01037.1 - 0.11 12.0 7.1 0.15 11.5 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) zf-CCHC PF00098.18 EGG01037.1 - 9.4 6.3 7.2 2 8.4 2.6 1.7 2 0 0 2 2 2 0 Zinc knuckle Saccharop_dh PF03435.13 EGG01038.1 - 7.9e-101 337.8 0.0 1.3e-100 337.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 EGG01038.1 - 2.1e-86 288.8 0.0 4.2e-86 287.8 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase Shikimate_DH PF01488.15 EGG01038.1 - 3.7e-07 30.3 0.2 2.5e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EGG01038.1 - 0.00067 19.1 0.1 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGG01038.1 - 0.005 15.5 0.0 0.0096 14.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_12 PF08242.7 EGG01038.1 - 0.01 16.3 0.0 1.3 9.5 0.0 2.9 2 0 0 2 2 2 0 Methyltransferase domain F420_oxidored PF03807.12 EGG01038.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF2325 PF10087.4 EGG01038.1 - 0.1 12.4 0.4 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) NAD_binding_10 PF13460.1 EGG01038.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding HMG_box PF00505.14 EGG01039.1 - 1.9e-14 53.6 0.5 3.8e-14 52.7 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGG01039.1 - 0.0008 19.7 0.5 0.0023 18.2 0.3 1.8 1 1 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EGG01039.1 - 0.0099 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 GARS_N PF02844.10 EGG01039.1 - 0.2 12.1 0.0 0.42 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Sugar_tr PF00083.19 EGG01040.1 - 2e-104 349.7 15.1 2.3e-104 349.5 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG01040.1 - 1e-28 100.0 48.5 8.8e-28 97.0 16.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGG01040.1 - 0.056 13.2 0.2 0.056 13.2 0.1 2.7 3 0 0 3 3 3 0 MFS_1 like family YABBY PF04690.8 EGG01043.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 YABBY protein YcbB PF08664.5 EGG01043.1 - 0.13 12.0 0.8 0.68 9.7 0.1 2.4 3 0 0 3 3 3 0 YcbB domain Ribosomal_L36 PF00444.13 EGG01045.1 - 1.1e-18 66.9 9.6 1.6e-18 66.4 6.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 EGG01045.1 - 0.029 13.6 0.2 0.048 12.9 0.1 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Hce2 PF14856.1 EGG01046.1 - 5.5e-06 26.2 3.3 0.00098 18.9 0.6 2.3 2 0 0 2 2 2 2 Pathogen effector; putative necrosis-inducing factor DUF771 PF05595.6 EGG01046.1 - 0.063 13.1 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF771) DUF719 PF05334.8 EGG01046.1 - 0.082 12.9 0.6 9.6 6.1 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF719) DUF164 PF02591.10 EGG01046.1 - 0.21 11.4 3.1 2.7 7.9 0.2 3.1 2 1 1 3 3 3 0 Putative zinc ribbon domain Barwin PF00967.12 EGG01047.1 - 0.01 15.5 0.2 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 Barwin family GTP_EFTU PF00009.22 EGG01048.1 - 6.4e-59 198.5 0.3 9.1e-59 198.0 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGG01048.1 - 7.7e-25 86.9 0.0 1.8e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGG01048.1 - 1.7e-14 53.7 2.0 3.8e-14 52.5 1.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGG01048.1 - 1e-05 25.4 0.1 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EGG01048.1 - 0.0034 16.9 0.1 0.0081 15.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EGG01048.1 - 0.0073 16.8 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EGG01048.1 - 0.11 11.9 0.1 5.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TPR_11 PF13414.1 EGG01049.1 - 1.8e-45 152.4 13.4 2.1e-15 56.0 0.3 6.3 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 EGG01049.1 - 4.4e-31 105.2 8.8 2.9e-06 26.6 0.0 8.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 EGG01049.1 - 7.8e-26 87.8 10.3 0.0012 18.6 0.0 10.1 10 1 1 11 11 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 EGG01049.1 - 3.6e-22 78.0 6.2 1.5e-05 24.7 0.0 7.2 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGG01049.1 - 9.6e-17 61.1 9.2 0.0036 17.9 0.0 7.0 6 2 2 8 8 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGG01049.1 - 1.6e-15 55.5 4.3 0.0029 17.2 0.0 8.0 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGG01049.1 - 7e-14 50.7 0.5 0.015 15.4 0.0 8.3 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGG01049.1 - 1.6e-10 40.6 4.4 0.088 13.4 0.0 8.6 3 3 7 10 10 10 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGG01049.1 - 4.6e-10 39.7 0.9 0.072 13.4 0.1 5.6 4 2 2 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EGG01049.1 - 9.2e-10 38.5 12.4 0.34 11.0 0.1 5.3 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGG01049.1 - 1.2e-07 31.0 2.4 0.59 10.0 0.1 6.6 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 EGG01049.1 - 0.00037 19.6 6.6 0.59 9.1 0.0 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGG01049.1 - 0.00046 19.9 5.4 1.2 9.0 0.0 5.3 4 1 2 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.3 EGG01049.1 - 0.00068 18.5 27.6 0.11 11.2 0.0 4.9 3 2 2 5 5 5 2 NMDA receptor-regulated protein 1 MIT PF04212.13 EGG01049.1 - 0.0023 17.7 10.6 0.088 12.7 0.3 4.3 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain DUF1510 PF07423.6 EGG01049.1 - 0.014 14.7 10.3 0.023 14.0 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ABC2_membrane_3 PF12698.2 EGG01049.1 - 0.02 13.9 1.1 0.03 13.3 0.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein TPR_6 PF13174.1 EGG01049.1 - 0.029 14.8 9.4 83 3.9 0.1 7.1 9 0 0 9 9 6 0 Tetratricopeptide repeat FancD2 PF14631.1 EGG01049.1 - 0.089 9.8 7.0 0.13 9.3 4.9 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF3560 PF12083.3 EGG01049.1 - 4 7.4 8.9 0.72 9.9 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3560) Rotamase PF00639.16 EGG01050.1 - 2.8e-20 72.8 0.2 5.1e-20 72.0 0.1 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EGG01050.1 - 1.1e-17 64.3 0.0 1.6e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EGG01050.1 - 2.4e-05 24.0 0.5 2.4e-05 24.0 0.4 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 EGG01050.1 - 0.04 14.5 0.0 0.052 14.1 0.0 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain MARVEL PF01284.18 EGG01052.1 - 1.1e-06 28.5 5.5 2.3e-06 27.4 3.9 1.5 1 1 0 1 1 1 1 Membrane-associating domain Lig_chan PF00060.21 EGG01052.1 - 0.0054 16.4 0.3 0.0083 15.8 0.2 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel YIF1 PF03878.10 EGG01052.1 - 0.011 14.9 0.1 0.015 14.4 0.1 1.1 1 0 0 1 1 1 0 YIF1 MscS_TM PF12794.2 EGG01052.1 - 0.093 11.3 5.6 0.11 11.0 3.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4149 PF13664.1 EGG01052.1 - 3.2 7.8 8.1 3.3 7.8 4.3 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Tetraspannin PF00335.15 EGG01052.1 - 4.1 6.6 11.8 0.091 12.0 2.6 1.9 1 1 1 2 2 2 0 Tetraspanin family DUF4118 PF13493.1 EGG01052.1 - 8.8 6.5 13.5 2.1 8.6 2.7 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4118) DUF2207 PF09972.4 EGG01052.1 - 9.2 4.7 6.1 1.7 7.1 1.4 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF2012 PF09430.5 EGG01053.1 - 2.3e-18 66.1 0.0 3.9e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SpoIIIAC PF06686.6 EGG01053.1 - 0.26 11.1 1.7 0.49 10.2 1.2 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AC/AD protein family CN_hydrolase PF00795.17 EGG01054.1 - 6.7e-13 48.4 0.0 8.5e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Abhydrolase_6 PF12697.2 EGG01055.1 - 1.3e-12 48.0 2.8 1.9e-12 47.5 1.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG01055.1 - 2.9e-11 43.3 0.0 5.1e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG01055.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGG01055.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 EGG01055.1 - 0.017 14.3 0.0 0.032 13.4 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EGG01055.1 - 0.074 12.4 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Pro_isomerase PF00160.16 EGG01056.1 - 3.2e-49 167.1 0.0 4.6e-48 163.3 0.0 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 EGG01056.1 - 2.1e-05 24.4 1.2 0.00042 20.2 0.0 2.9 2 1 1 3 3 3 1 U-box domain Rtf2 PF04641.7 EGG01056.1 - 0.0038 16.4 0.0 0.0038 16.4 0.0 2.1 2 1 0 2 2 2 1 Rtf2 RING-finger TrbI_Ftype PF09677.5 EGG01056.1 - 0.063 13.1 0.2 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Snf7 PF03357.16 EGG01057.1 - 7.1e-33 113.3 19.8 9.1e-33 113.0 13.7 1.0 1 0 0 1 1 1 1 Snf7 CDRT4 PF15213.1 EGG01057.1 - 0.11 12.5 6.6 0.72 9.9 0.2 2.6 2 1 1 3 3 3 0 CMT1A duplicated region transcript 4 protein Invas_SpaK PF03519.9 EGG01057.1 - 0.12 12.2 1.4 0.39 10.5 0.1 2.3 2 1 0 2 2 2 0 Invasion protein B family PT-HINT PF07591.6 EGG01057.1 - 0.16 11.8 0.8 0.24 11.2 0.5 1.3 1 0 0 1 1 1 0 Pretoxin HINT domain DUF272 PF03312.10 EGG01057.1 - 0.16 12.1 1.3 0.24 11.6 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF272) DUF3641 PF12345.3 EGG01057.1 - 0.22 11.3 1.8 1.3 8.8 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) Lumazine_bd PF12870.2 EGG01058.1 - 0.0063 16.5 0.2 0.008 16.2 0.1 1.1 1 0 0 1 1 1 1 Lumazine-binding domain Ribul_P_3_epim PF00834.14 EGG01059.1 - 1e-62 210.8 0.0 1.3e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family JmjN PF02375.12 EGG01059.1 - 0.014 14.8 0.0 0.054 13.0 0.0 1.9 2 0 0 2 2 2 0 jmjN domain PG_binding_3 PF09374.5 EGG01059.1 - 0.032 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Ribosomal_S7 PF00177.16 EGG01060.1 - 1.9e-23 82.7 0.0 2.7e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e NID PF07292.8 EGG01060.1 - 0.037 14.0 0.2 0.088 12.8 0.1 1.6 1 0 0 1 1 1 0 Nmi/IFP 35 domain (NID) DUF370 PF04025.7 EGG01062.1 - 0.13 12.3 0.7 5 7.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF370) MIS13 PF08202.6 EGG01063.1 - 0.016 14.3 0.1 0.029 13.4 0.1 1.4 1 0 0 1 1 1 0 Mis12-Mtw1 protein family OTU PF02338.14 EGG01064.1 - 6.3e-05 23.5 0.0 0.00014 22.4 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Cellulase PF00150.13 EGG01066.1 - 5.3e-40 137.4 0.0 6.9e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.13 EGG01067.1 - 8.5e-42 143.2 0.0 9.7e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) S_tail_recep_bd PF14928.1 EGG01067.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain Carb_bind PF10645.4 EGG01068.1 - 0.098 12.4 1.5 0.21 11.4 1.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding ENTH PF01417.15 EGG01069.1 - 1.7e-47 160.3 0.1 2.7e-47 159.7 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EGG01069.1 - 0.00011 21.0 0.9 0.00015 20.5 0.0 1.7 2 0 0 2 2 2 1 ANTH domain DUF1635 PF07795.6 EGG01069.1 - 0.0015 17.9 2.4 0.13 11.6 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1635) YbjQ_1 PF01906.12 EGG01070.1 - 0.0018 18.7 0.1 0.15 12.4 0.0 2.1 2 0 0 2 2 2 2 Putative heavy-metal-binding Tropomyosin PF00261.15 EGG01071.1 - 0.0055 15.8 2.1 0.0095 15.0 1.4 1.2 1 0 0 1 1 1 1 Tropomyosin TMCO5 PF14992.1 EGG01071.1 - 0.01 15.0 0.8 0.016 14.3 0.6 1.2 1 0 0 1 1 1 0 TMCO5 family TPR_MLP1_2 PF07926.7 EGG01071.1 - 0.098 12.3 1.9 0.15 11.7 1.3 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 EGG01071.1 - 0.26 11.1 3.0 0.45 10.3 2.1 1.3 1 0 0 1 1 1 0 Tropomyosin like BAR_2 PF10455.4 EGG01073.1 - 2.4e-46 157.9 3.0 6.2e-46 156.6 2.1 1.6 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EGG01073.1 - 1.7e-11 44.0 5.4 2.2e-10 40.4 3.7 2.0 1 1 0 1 1 1 1 BAR domain Phasin PF05597.6 EGG01073.1 - 0.0068 16.1 0.1 0.0068 16.1 0.1 2.3 2 1 1 3 3 3 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Uds1 PF15456.1 EGG01073.1 - 0.16 11.9 0.3 0.16 11.9 0.2 2.8 3 1 0 3 3 3 0 Up-regulated During Septation Exonuc_VII_L PF02601.10 EGG01073.1 - 0.42 9.7 7.8 0.45 9.6 0.4 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.7 EGG01073.1 - 3.4 7.5 9.1 0.29 10.9 0.2 3.0 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FA_hydroxylase PF04116.8 EGG01074.1 - 8.9e-15 55.0 17.8 8.9e-15 55.0 12.4 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily ThiF PF00899.16 EGG01074.1 - 0.048 13.4 0.2 0.083 12.7 0.1 1.4 1 0 0 1 1 1 0 ThiF family GATase PF00117.23 EGG01076.1 - 6.1e-06 25.8 0.1 3.2e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I NAD_kinase PF01513.16 EGG01077.1 - 2.4e-56 190.5 0.0 3.2e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EGG01077.1 - 0.0033 16.8 0.0 0.0064 15.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ribosomal_S19 PF00203.16 EGG01078.1 - 1.6e-23 82.1 0.0 2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 PC_rep PF01851.17 EGG01079.1 - 7.6e-47 154.9 20.8 5.4e-10 38.9 0.0 9.5 10 0 0 10 10 10 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EGG01079.1 - 2.1e-22 79.2 5.9 4.9e-11 42.7 0.1 5.5 3 2 4 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 EGG01079.1 - 6.7e-08 32.7 1.4 0.0018 18.7 0.0 5.3 4 1 2 6 6 6 1 HEAT-like repeat HEAT PF02985.17 EGG01079.1 - 5.4e-07 29.1 0.4 0.68 10.1 0.0 4.5 3 0 0 3 3 3 2 HEAT repeat HEAT_PBS PF03130.11 EGG01079.1 - 0.0097 16.2 0.9 4 8.1 0.0 4.1 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat Arm PF00514.18 EGG01079.1 - 0.098 12.5 0.7 18 5.3 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 EGG01079.1 - 0.15 12.0 0.2 19 5.2 0.0 3.6 2 2 1 3 3 3 0 Importin-beta N-terminal domain PMT PF02366.13 EGG01080.1 - 5.1e-79 265.1 19.9 5.1e-79 265.1 13.8 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGG01080.1 - 4.9e-39 133.8 1.4 4.9e-39 133.8 1.0 2.6 2 1 1 3 3 3 1 MIR domain Mre11_DNA_bind PF04152.9 EGG01081.1 - 9e-49 165.6 0.3 1.2e-48 165.3 0.2 1.1 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EGG01081.1 - 7.1e-24 84.3 1.1 1.1e-23 83.6 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGG01081.1 - 4e-06 26.7 0.0 1.3e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Daxx PF03344.10 EGG01082.1 - 0.075 11.5 13.2 0.085 11.3 9.2 1.1 1 0 0 1 1 1 0 Daxx Family COPI_C PF06957.6 EGG01082.1 - 1.9 6.9 10.4 2.6 6.4 7.2 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.7 EGG01082.1 - 4.6 5.0 17.8 6.1 4.6 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.7 EGG01082.1 - 5.8 6.7 9.2 9.5 6.0 6.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FA_desaturase PF00487.19 EGG01083.1 - 0.00028 20.4 1.0 0.00039 19.9 0.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Mre11_DNA_bind PF04152.9 EGG01084.1 - 6.4e-05 22.8 0.1 6.4e-05 22.8 0.0 3.0 3 2 0 3 3 3 1 Mre11 DNA-binding presumed domain Sugar_tr PF00083.19 EGG01085.1 - 8.1e-104 347.7 17.6 9.2e-104 347.5 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG01085.1 - 5e-30 104.3 24.9 5e-30 104.3 17.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EGG01085.1 - 0.00013 20.4 22.4 0.0017 16.8 4.5 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein DUF4218 PF13960.1 EGG01090.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Zn_clus PF00172.13 EGG01091.1 - 0.48 10.3 7.0 2.9 7.8 1.4 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sad1_UNC PF07738.8 EGG01096.1 - 8.1e-27 93.6 0.0 1.1e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Imm31 PF15595.1 EGG01098.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 31 Peptidase_M18 PF02127.10 EGG01100.1 - 2.1e-11 43.0 0.4 2.3e-06 26.4 0.0 3.4 1 1 3 4 4 4 3 Aminopeptidase I zinc metalloprotease (M18) Suc_Fer-like PF06999.7 EGG01101.1 - 3.9e-30 105.5 0.3 1e-28 100.9 0.0 2.6 2 1 0 2 2 2 1 Sucrase/ferredoxin-like HSCB_C PF07743.8 EGG01103.1 - 1.7e-10 41.2 5.3 1.7e-10 41.2 3.6 1.5 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EGG01103.1 - 1.6e-08 34.1 0.0 2.1e-07 30.5 0.0 2.6 2 1 1 3 3 3 1 DnaJ domain Rpr2 PF04032.11 EGG01103.1 - 0.11 12.3 0.9 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_3 PF14369.1 EGG01103.1 - 0.15 12.0 1.5 13 5.8 0.1 2.5 2 0 0 2 2 2 0 zinc-finger zf-ribbon_3 PF13248.1 EGG01103.1 - 0.85 8.9 4.7 2.6 7.3 3.3 1.8 1 1 0 1 1 1 0 zinc-ribbon domain YCII PF03795.9 EGG01104.1 - 9.5e-06 25.7 0.0 1.2e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Cpn60_TCP1 PF00118.19 EGG01105.1 - 9.1e-120 400.5 8.0 1.1e-119 400.3 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1373 PF07117.6 EGG01107.1 - 0.01 15.6 1.2 0.01 15.6 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) RCR PF12273.3 EGG01107.1 - 0.12 12.9 0.5 0.14 12.7 0.3 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Macoilin PF09726.4 EGG01108.1 - 2.9 6.0 8.8 3.3 5.8 6.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Dicty_REP PF05086.7 EGG01108.1 - 3 5.5 10.7 3.5 5.2 7.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.5 EGG01108.1 - 7.1 4.9 6.3 8.9 4.5 4.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cu-oxidase_3 PF07732.10 EGG01109.1 - 1.5e-42 144.0 5.2 5.6e-42 142.1 0.3 3.0 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG01109.1 - 3.5e-35 120.4 2.9 2.4e-30 104.8 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGG01109.1 - 3.5e-24 85.4 0.1 8.1e-23 81.0 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase zf-DHHC PF01529.15 EGG01113.1 - 3.4e-31 107.9 14.9 3.7e-31 107.8 10.3 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase SCAMP PF04144.8 EGG01113.1 - 0.025 14.4 1.4 0.031 14.1 1.0 1.1 1 0 0 1 1 1 0 SCAMP family MFS_1_like PF12832.2 EGG01113.1 - 0.069 12.9 2.9 0.1 12.3 0.2 2.0 2 0 0 2 2 2 0 MFS_1 like family NADH_dehy_S2_C PF06444.6 EGG01113.1 - 1.2 9.4 7.6 3.2 8.1 5.2 1.7 1 1 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus Sigma_reg_N PF13800.1 EGG01113.1 - 6.9 6.7 10.9 2.2 8.3 1.0 2.1 1 1 1 2 2 2 0 Sigma factor regulator N-terminal Antimicrobial10 PF08105.6 EGG01115.1 - 6.1 6.5 8.4 0.74 9.4 1.7 2.6 2 0 0 2 2 2 0 Metchnikowin family Alpha_kinase PF02816.13 EGG01117.1 - 4.2e-09 36.3 0.3 4.8e-09 36.1 0.2 1.0 1 0 0 1 1 1 1 Alpha-kinase family DUF1168 PF06658.7 EGG01120.1 - 2.3 7.7 10.5 0.23 10.9 4.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) SBDS PF01172.13 EGG01121.1 - 0.084 12.6 0.2 0.83 9.4 0.0 2.0 2 0 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein HIGH_NTase1 PF05636.6 EGG01121.1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase ANAPC15 PF15243.1 EGG01121.1 - 0.16 12.0 1.3 0.18 11.8 0.9 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DS PF01916.12 EGG01122.1 - 4.4e-06 26.0 0.0 5e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF3904 PF13044.1 EGG01123.1 - 0.063 11.6 0.3 0.067 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3904) zf-BED PF02892.10 EGG01124.1 - 1.1e-05 25.0 1.2 8.9e-05 22.1 0.9 2.0 1 1 0 1 1 1 1 BED zinc finger Beta_elim_lyase PF01212.16 EGG01125.1 - 7.7e-68 228.7 0.0 9.3e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DUF851 PF05867.6 EGG01125.1 - 0.024 13.8 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF851) Aminotran_5 PF00266.14 EGG01125.1 - 0.055 12.1 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGG01125.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-TFIIB PF13453.1 EGG01127.1 - 0.11 11.7 0.2 0.22 10.7 0.1 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger PDEase_I PF00233.14 EGG01128.1 - 4.9e-35 121.4 0.0 5.7e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase tRNA-synt_1d PF00750.14 EGG01130.1 - 6e-88 295.0 2.1 7.7e-88 294.6 1.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EGG01130.1 - 3.3e-18 65.7 0.0 5.8e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EGG01130.1 - 0.032 14.7 0.0 0.073 13.6 0.0 1.6 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain ATG16 PF08614.6 EGG01131.1 - 3.4e-36 124.9 20.9 4e-36 124.6 14.5 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 EGG01131.1 - 0.0049 16.6 3.4 0.0049 16.6 2.4 2.9 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 EGG01131.1 - 0.006 16.8 3.3 0.006 16.8 2.3 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF904) zf-C4H2 PF10146.4 EGG01131.1 - 0.077 13.0 3.4 0.12 12.3 2.4 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein DUF812 PF05667.6 EGG01131.1 - 0.082 11.4 9.9 0.098 11.1 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Phage_int_SAM_2 PF12834.2 EGG01131.1 - 0.13 12.7 8.5 1.3 9.4 0.6 2.6 1 1 1 2 2 2 0 Phage integrase, N-terminal DUF3552 PF12072.3 EGG01131.1 - 0.39 9.9 21.1 1.3 8.2 10.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) GAS PF13851.1 EGG01131.1 - 1.4 8.0 16.4 0.16 11.1 7.4 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2216 PF10226.4 EGG01131.1 - 1.6 8.1 12.1 0.88 9.0 6.5 2.0 2 1 1 3 3 3 0 Uncharacterized conserved proteins (DUF2216) DUF4407 PF14362.1 EGG01131.1 - 2 7.2 17.7 4.2 6.2 12.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF972 PF06156.8 EGG01131.1 - 3.3 8.1 16.9 0.7 10.2 2.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF4201 PF13870.1 EGG01131.1 - 3.3 7.1 19.4 4.5 6.6 9.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) USP8_interact PF08941.5 EGG01131.1 - 4 6.7 8.6 1.1 8.5 1.4 2.5 2 1 0 2 2 2 0 USP8 interacting RasGAP_C PF03836.10 EGG01131.1 - 4.1 7.0 10.5 0.36 10.5 3.9 1.8 2 1 0 2 2 2 0 RasGAP C-terminus IncA PF04156.9 EGG01131.1 - 9.8 5.7 21.6 1.5 8.3 10.9 2.2 2 1 0 2 2 2 0 IncA protein COG2 PF06148.6 EGG01131.1 - 9.8 6.0 13.1 2.9 7.7 5.6 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Pex24p PF06398.6 EGG01132.1 - 2.8e-36 125.0 19.6 1.2e-35 123.0 13.6 1.8 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Phage_int_SAM_3 PF14659.1 EGG01133.1 - 0.17 12.1 4.2 1.8 8.9 0.0 3.5 3 2 1 4 4 4 0 Phage integrase, N-terminal SAM-like domain DUF3713 PF12506.3 EGG01134.1 - 0.29 11.2 0.0 0.29 11.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3713) PfkB PF00294.19 EGG01136.1 - 6.3e-11 41.9 0.0 5.8e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EGG01136.1 - 5.3e-10 38.9 0.0 1.2e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DUF3605 PF12239.3 EGG01137.1 - 4.7e-13 49.2 0.2 4.7e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) GCM PF03615.10 EGG01138.1 - 0.00032 20.2 1.6 0.00071 19.1 1.1 1.6 1 0 0 1 1 1 1 GCM motif protein FBPase_3 PF01950.11 EGG01138.1 - 0.16 10.9 0.7 0.24 10.3 0.5 1.2 1 0 0 1 1 1 0 Fructose-1,6-bisphosphatase CBFD_NFYB_HMF PF00808.18 EGG01139.1 - 1.4e-08 34.6 0.1 7e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.9 EGG01139.1 - 0.0073 16.0 1.2 0.024 14.4 0.0 2.4 3 0 0 3 3 3 1 hTAFII28-like protein conserved region Myc_N PF01056.13 EGG01139.1 - 6.3 5.8 15.6 12 4.9 10.8 1.5 1 1 0 1 1 1 0 Myc amino-terminal region TFIIB PF00382.14 EGG01140.1 - 1.8e-38 130.1 0.0 4.3e-19 68.0 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EGG01140.1 - 3.2e-21 75.3 2.4 3.2e-21 75.3 1.7 3.9 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EGG01140.1 - 5.1e-10 38.4 2.7 5.1e-10 38.4 1.9 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.18 EGG01140.1 - 1.5e-06 27.7 0.0 0.0057 16.2 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Lar_restr_allev PF14354.1 EGG01140.1 - 0.004 17.4 0.6 0.014 15.7 0.4 1.9 1 0 0 1 1 1 1 Restriction alleviation protein Lar RRN7 PF11781.3 EGG01140.1 - 0.005 16.3 0.4 0.009 15.4 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Ribosomal_S27e PF01667.12 EGG01140.1 - 0.062 12.8 1.3 0.15 11.6 0.9 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 Rubredoxin PF00301.15 EGG01140.1 - 0.53 10.2 3.2 0.72 9.7 0.1 2.5 2 0 0 2 2 2 0 Rubredoxin ESAG1 PF03238.8 EGG01141.1 - 0.092 12.0 0.6 0.12 11.6 0.4 1.4 1 1 0 1 1 1 0 ESAG protein Pox_Ag35 PF03286.9 EGG01142.1 - 0.4 10.1 8.8 0.44 10.0 5.4 1.5 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Peptidase_A6 PF01829.11 EGG01143.1 - 0.062 12.3 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase A6 family Inositol_P PF00459.20 EGG01147.1 - 8.8e-70 235.0 0.0 1.1e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DPBB_1 PF03330.13 EGG01149.1 - 1e-09 38.2 0.3 3.8e-08 33.2 0.0 3.3 4 0 0 4 4 4 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF4175 PF13779.1 EGG01149.1 - 0.011 13.4 2.0 0.099 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Barwin PF00967.12 EGG01149.1 - 0.019 14.6 0.1 0.053 13.1 0.1 1.7 1 0 0 1 1 1 0 Barwin family DUF3306 PF11748.3 EGG01150.1 - 0.0095 16.5 0.6 0.02 15.5 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3306) Symplekin_C PF12295.3 EGG01151.1 - 4.7e-53 179.8 2.4 7e-52 176.0 0.4 2.9 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 EGG01151.1 - 5.4e-35 120.9 2.9 1.4e-34 119.5 2.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) ABC2_membrane PF01061.19 EGG01152.1 - 1.6e-63 213.6 63.6 2.1e-33 115.2 14.9 3.3 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGG01152.1 - 5.4e-30 104.4 0.0 2e-15 57.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGG01152.1 - 7.3e-28 96.2 0.2 3.8e-22 77.9 0.0 3.3 4 0 0 4 4 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EGG01152.1 - 3.2e-05 23.1 37.0 6.6e-05 22.0 9.6 3.1 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 EGG01152.1 - 0.00014 21.3 0.4 0.026 13.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGG01152.1 - 0.00077 18.6 0.0 0.0017 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_trans_N PF14510.1 EGG01152.1 - 0.0011 18.9 0.1 0.0049 16.9 0.0 2.1 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 EGG01152.1 - 0.0013 18.2 0.1 0.012 15.0 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGG01152.1 - 0.0034 17.3 0.1 1.8 8.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.1 EGG01152.1 - 0.0061 16.5 0.2 0.43 10.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EGG01152.1 - 0.012 14.8 0.0 1.4 8.0 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EGG01152.1 - 0.025 14.5 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EGG01152.1 - 0.03 13.3 0.0 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EGG01152.1 - 0.034 14.2 0.1 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGG01152.1 - 0.04 13.9 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 EGG01152.1 - 0.064 12.7 0.8 0.12 11.8 0.6 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EGG01152.1 - 0.23 11.0 0.8 1 9.0 0.1 2.4 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 Trefoil PF00088.13 EGG01153.1 - 0.21 11.2 3.0 0.41 10.3 2.1 1.4 1 0 0 1 1 1 0 Trefoil (P-type) domain DUF948 PF06103.6 EGG01156.1 - 0.0011 18.7 0.8 0.0051 16.6 0.4 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 EGG01156.1 - 0.0016 18.2 1.6 0.0045 16.7 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 EGG01156.1 - 0.0073 16.4 0.8 0.16 12.1 0.6 2.7 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 EGG01156.1 - 0.0085 16.3 2.0 0.018 15.3 0.8 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 EGG01156.1 - 0.0096 15.6 0.8 0.06 13.1 0.2 2.1 1 1 0 1 1 1 1 Laminin Domain II Baculo_PEP_C PF04513.7 EGG01156.1 - 0.013 15.3 2.7 0.035 13.9 1.4 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.16 EGG01156.1 - 0.016 14.8 0.4 0.033 13.7 0.3 1.5 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Hormone_1 PF00103.15 EGG01156.1 - 0.018 14.4 0.4 0.082 12.2 0.3 1.8 1 1 1 2 2 2 0 Somatotropin hormone family Syntaxin PF00804.20 EGG01156.1 - 0.046 13.8 0.3 0.26 11.4 0.1 2.4 1 1 1 2 2 2 0 Syntaxin BicD PF09730.4 EGG01156.1 - 0.054 11.8 0.0 0.064 11.6 0.0 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D LXG PF04740.7 EGG01156.1 - 0.068 12.9 0.4 0.15 11.8 0.3 1.7 1 0 0 1 1 1 0 LXG domain of WXG superfamily EzrA PF06160.7 EGG01156.1 - 0.069 11.3 0.5 0.11 10.6 0.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Reo_sigmaC PF04582.7 EGG01156.1 - 0.091 11.9 1.8 0.09 11.9 0.5 1.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein HsbA PF12296.3 EGG01156.1 - 0.13 12.0 0.6 9.5 6.0 0.0 2.9 2 1 1 3 3 3 0 Hydrophobic surface binding protein A FlaC_arch PF05377.6 EGG01156.1 - 0.17 11.7 2.6 0.14 12.0 0.5 2.0 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) COG2 PF06148.6 EGG01156.1 - 0.32 10.8 2.2 0.62 9.9 0.4 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HAD_2 PF13419.1 EGG01157.1 - 5.8e-18 65.7 0.0 5e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGG01157.1 - 8.7e-07 29.5 0.0 1.1e-06 29.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGG01157.1 - 0.00044 19.9 0.0 0.00081 19.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EGG01157.1 - 0.007 16.5 0.0 0.012 15.7 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MMS19_N PF14500.1 EGG01162.1 - 2.3e-65 220.4 0.0 5.1e-64 216.0 0.0 2.4 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EGG01162.1 - 1.4e-59 201.8 0.0 1.8e-58 198.2 0.0 2.6 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 EGG01162.1 - 0.00033 20.8 0.2 0.066 13.4 0.0 3.0 2 0 0 2 2 2 1 HEAT repeats ParcG PF10274.4 EGG01162.1 - 0.043 13.7 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 Parkin co-regulated protein DS PF01916.12 EGG01162.1 - 0.081 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Deoxyhypusine synthase HEAT_EZ PF13513.1 EGG01162.1 - 0.74 10.3 10.2 33 5.1 0.3 5.2 4 1 1 5 5 5 0 HEAT-like repeat Gly-zipper_OmpA PF13436.1 EGG01163.1 - 0.083 12.5 2.9 0.11 12.2 2.0 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain TMP_2 PF06791.8 EGG01163.1 - 0.34 10.4 1.6 0.47 10.0 1.1 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein GPI-anchored PF10342.4 EGG01164.1 - 8.3e-10 39.0 0.2 1.5e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GTP_EFTU PF00009.22 EGG01165.1 - 1.2e-47 161.7 0.0 1.9e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EGG01165.1 - 4e-35 119.9 0.6 9.1e-35 118.8 0.4 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EGG01165.1 - 2.1e-16 59.5 0.0 4.5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 EGG01165.1 - 5.1e-06 26.4 0.0 9.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EGG01165.1 - 5.2e-05 23.2 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EGG01165.1 - 0.00029 20.3 0.0 0.00094 18.6 0.0 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation EFG_II PF14492.1 EGG01165.1 - 0.0015 18.3 0.2 0.013 15.3 0.1 2.5 2 1 0 2 2 2 1 Elongation Factor G, domain II ATP_bind_1 PF03029.12 EGG01165.1 - 0.002 17.7 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.17 EGG01165.1 - 0.0021 17.4 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG01165.1 - 0.0064 16.9 0.1 0.014 15.8 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGG01165.1 - 0.053 12.7 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Phage_Mu_Gam PF07352.7 EGG01166.1 - 0.85 9.1 9.8 6.8 6.2 2.8 2.7 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein Lumazine_bd PF12870.2 EGG01166.1 - 4.4 7.3 13.1 11 6.1 2.7 3.3 2 1 1 3 3 3 0 Lumazine-binding domain Bac_small_YrzI PF09501.5 EGG01166.1 - 9.2 6.2 8.4 0.31 10.9 0.2 2.7 3 0 0 3 3 3 0 Probable sporulation protein (Bac_small_yrzI) DUF2203 PF09969.4 EGG01166.1 - 9.5 6.4 8.4 5.7 7.1 1.1 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) PCNA_N PF00705.13 EGG01168.1 - 1.8e-53 179.3 8.1 1.2e-52 176.6 4.5 2.2 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EGG01168.1 - 3e-46 156.4 0.3 8.5e-46 155.0 0.0 1.8 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EGG01168.1 - 5e-07 29.1 0.3 6.2e-07 28.7 0.2 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EGG01168.1 - 0.00075 18.5 0.2 0.0022 16.9 0.2 1.8 1 1 0 1 1 1 1 Hus1-like protein DUF188 PF02639.9 EGG01169.1 - 0.042 13.3 1.1 0.077 12.4 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 DUF1875 PF08961.5 EGG01170.1 - 0.043 13.1 3.1 0.075 12.3 1.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1875) SPASM PF13186.1 EGG01171.1 - 0.15 12.4 0.4 0.33 11.3 0.3 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster-binding domain DltD_M PF04918.7 EGG01171.1 - 0.66 10.1 6.5 0.76 9.9 4.1 1.4 1 1 0 1 1 1 0 DltD central region Med15 PF09606.5 EGG01173.1 - 0.017 13.3 42.2 0.02 13.1 29.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 EGG01173.1 - 0.056 13.8 15.8 0.068 13.5 11.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3523 PF12037.3 EGG01173.1 - 0.46 9.4 33.4 0.75 8.7 23.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) SMN PF06003.7 EGG01173.1 - 0.49 9.4 3.0 0.67 9.0 2.1 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) SprA-related PF12118.3 EGG01173.1 - 0.8 8.9 29.2 1.2 8.3 20.2 1.3 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.8 EGG01173.1 - 0.82 9.5 28.7 1.1 9.1 19.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MRI PF15325.1 EGG01173.1 - 2 9.4 14.1 1.3 9.9 0.1 3.2 2 1 1 3 3 3 0 Modulator of retrovirus infection PAT1 PF09770.4 EGG01173.1 - 2.6 6.1 40.4 3.1 5.9 28.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Slu7 PF11708.3 EGG01173.1 - 4.1 7.0 16.2 6 6.5 11.2 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF4045 PF13254.1 EGG01173.1 - 5.2 6.2 15.9 6.8 5.8 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) AAA_23 PF13476.1 EGG01173.1 - 7.4 6.8 21.2 10 6.4 14.7 1.2 1 0 0 1 1 1 0 AAA domain Asp-B-Hydro_N PF05279.6 EGG01173.1 - 8.4 6.1 16.4 12 5.6 11.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region VPS28 PF03997.7 EGG01174.1 - 4.8e-46 156.7 0.0 5.4e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein START PF01852.14 EGG01175.1 - 2.1e-16 59.8 0.1 4.1e-08 32.8 0.0 3.7 3 1 0 3 3 3 3 START domain Ubiq_cyt_C_chap PF03981.7 EGG01176.1 - 5.4e-22 78.1 0.0 9.2e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone APG6 PF04111.7 EGG01177.1 - 1e-102 343.4 3.7 1.2e-102 343.2 2.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 GAS PF13851.1 EGG01177.1 - 0.05 12.7 9.9 0.082 12.0 6.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TraC PF07820.7 EGG01177.1 - 0.064 13.4 6.6 0.16 12.2 4.5 1.7 1 1 0 1 1 1 0 TraC-like protein V_ATPase_I PF01496.14 EGG01177.1 - 0.078 10.8 2.8 0.092 10.5 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IFT57 PF10498.4 EGG01177.1 - 0.15 10.7 10.8 0.28 9.8 7.4 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4530 PF15039.1 EGG01177.1 - 0.17 11.7 4.1 0.31 10.9 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Mu-like_Pro PF10123.4 EGG01177.1 - 0.48 9.8 3.5 0.83 9.0 2.4 1.3 1 0 0 1 1 1 0 Mu-like prophage I protein Med4 PF10018.4 EGG01177.1 - 0.54 9.6 7.5 0.24 10.7 3.6 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 SRF-TF PF00319.13 EGG01178.1 - 6.6e-23 79.6 0.0 7.4e-23 79.5 0.0 1.1 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) RF-1 PF00472.15 EGG01179.1 - 1e-19 70.3 0.3 1.6e-19 69.7 0.2 1.3 1 0 0 1 1 1 1 RF-1 domain ERG2_Sigma1R PF04622.7 EGG01181.1 - 9.1e-81 270.2 0.3 1.1e-80 270.0 0.2 1.1 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein PIP49_N PF14875.1 EGG01182.1 - 0.12 11.9 0.3 0.23 11.1 0.2 1.4 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 DUF4448 PF14610.1 EGG01183.1 - 2.6e-07 30.3 0.1 5.3e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EGG01183.1 - 0.005 17.2 2.0 0.01 16.2 1.4 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4342 PF14242.1 EGG01183.1 - 1.8 8.3 3.6 3.1 7.6 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) KAR9 PF08580.5 EGG01185.1 - 0.17 10.1 4.3 0.17 10.0 3.0 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 CAML PF14963.1 EGG01185.1 - 0.28 10.5 1.0 0.31 10.3 0.7 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand CAP_C PF08603.6 EGG01190.1 - 0.0083 15.4 0.8 0.01 15.1 0.5 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Kinocilin PF15033.1 EGG01190.1 - 0.066 12.7 0.0 0.096 12.2 0.0 1.2 1 1 0 1 1 1 0 Kinocilin protein MFMR PF07777.6 EGG01196.1 - 3.3 7.6 15.0 7 6.5 10.4 1.5 1 0 0 1 1 1 0 G-box binding protein MFMR FYVE_2 PF02318.11 EGG01198.1 - 0.35 10.7 2.8 0.46 10.4 1.9 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger DPRP PF04244.8 EGG01200.1 - 0.14 11.7 2.8 0.15 11.5 1.7 1.3 1 1 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein Tna_leader PF08053.6 EGG01203.1 - 0.049 13.0 1.4 0.087 12.2 1.0 1.4 1 0 0 1 1 1 0 Tryptophanese operon leader peptide p450 PF00067.17 EGG01204.1 - 8.2e-62 209.2 0.0 1e-61 208.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_41 PF14502.1 EGG01204.1 - 0.071 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DPPIV_N PF00930.16 EGG01205.1 - 1.1e-79 267.5 0.0 1.6e-79 267.1 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EGG01205.1 - 5e-45 153.3 1.0 8.7e-45 152.5 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGG01205.1 - 4.2e-08 33.0 0.1 8.4e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG01205.1 - 7.7e-06 25.9 0.1 2.2e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EGG01205.1 - 0.0047 16.3 0.7 0.018 14.4 0.6 1.8 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.4 EGG01205.1 - 0.027 13.7 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase AXE1 PF05448.7 EGG01205.1 - 0.046 12.2 0.0 0.093 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) LIP PF03583.9 EGG01205.1 - 0.12 11.5 0.2 1.6 7.8 0.1 2.1 2 0 0 2 2 2 0 Secretory lipase HIG_1_N PF04588.8 EGG01206.1 - 8.9e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Toprim PF01751.17 EGG01207.1 - 1.6e-06 27.9 0.0 2.6e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Toprim domain Carboxyl_trans PF01039.17 EGG01208.1 - 2.5e-141 471.4 0.1 3.2e-141 471.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EGG01208.1 - 0.073 12.2 0.0 8.2 5.5 0.0 2.3 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Cutinase PF01083.17 EGG01209.1 - 4.6e-28 98.1 0.0 6e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase DUF3089 PF11288.3 EGG01209.1 - 0.00035 19.8 0.0 0.00054 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) PE-PPE PF08237.6 EGG01209.1 - 0.002 17.6 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EGG01209.1 - 0.0024 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.2 EGG01209.1 - 0.0038 17.1 0.0 0.0043 16.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGG01209.1 - 0.0043 17.2 0.0 0.0065 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF3228 PF11539.3 EGG01209.1 - 0.076 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) Abhydrolase_5 PF12695.2 EGG01209.1 - 0.089 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_9 PF10081.4 EGG01209.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family SHS2_Rpb7-N PF03876.12 EGG01210.1 - 2.9e-14 52.9 0.0 5.3e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EGG01210.1 - 2.8e-13 49.7 0.0 5.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EGG01210.1 - 1.4e-05 25.2 0.0 2.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Requiem_N PF14051.1 EGG01211.1 - 0.0051 16.7 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. PAN_3 PF08277.7 EGG01214.1 - 0.15 11.6 0.3 2 8.0 0.0 2.2 2 0 0 2 2 2 0 PAN-like domain TMEM171 PF15471.1 EGG01216.1 - 0.35 9.6 5.4 0.75 8.5 3.8 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 Apis_Csd PF11671.3 EGG01216.1 - 0.88 9.3 24.2 0.11 12.3 4.3 2.7 3 0 0 3 3 3 0 Complementary sex determiner protein SMN PF06003.7 EGG01216.1 - 7.8 5.5 14.3 3.7 6.5 8.0 1.7 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) BNR PF02012.15 EGG01217.1 - 1.2e-05 24.3 43.8 0.23 11.4 0.1 11.4 11 0 0 11 11 11 4 BNR/Asp-box repeat CHB_HEX_C_1 PF13290.1 EGG01217.1 - 0.037 13.7 2.6 1.4 8.7 0.0 3.0 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Fe_dep_repr_C PF02742.10 EGG01217.1 - 0.073 12.7 0.0 3.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain CHB_HEX_C PF03174.8 EGG01217.1 - 0.09 12.6 0.6 4.7 7.1 0.1 2.6 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain UCR_UQCRX_QCR9 PF05365.7 EGG01217.1 - 3.3 7.4 5.5 21 4.8 0.3 3.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Spiralin PF05215.8 EGG01218.1 - 0.05 12.7 0.0 0.054 12.5 0.0 1.0 1 0 0 1 1 1 0 Spiralin NTF2 PF02136.15 EGG01220.1 - 0.00061 20.1 0.6 0.0011 19.3 0.4 1.5 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_3 PF13474.1 EGG01220.1 - 0.043 13.8 0.0 0.051 13.6 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain DUF605 PF04652.11 EGG01221.1 - 4.4 6.6 9.0 5.3 6.3 6.2 1.1 1 0 0 1 1 1 0 Vta1 like Pro-kuma_activ PF09286.6 EGG01224.1 - 6e-26 91.1 0.1 9.7e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGG01224.1 - 5.4e-09 35.6 0.1 9e-09 34.8 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Syntaxin_2 PF14523.1 EGG01225.1 - 2.4e-22 78.8 2.1 2.4e-22 78.8 1.5 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EGG01225.1 - 6.8e-16 57.7 2.1 6.8e-16 57.7 1.5 3.0 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 EGG01225.1 - 0.023 14.8 0.5 0.023 14.8 0.4 2.9 2 2 0 2 2 2 0 Syntaxin V-SNARE PF05008.10 EGG01225.1 - 0.08 13.1 1.9 0.26 11.4 0.1 2.7 2 2 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF2422 PF10337.4 EGG01225.1 - 0.09 11.5 3.0 0.14 10.9 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) MCPsignal PF00015.16 EGG01225.1 - 0.13 11.7 3.8 0.12 11.9 0.2 2.1 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.16 EGG01225.1 - 0.14 11.7 3.6 0.33 10.5 1.2 2.5 2 1 0 2 2 2 0 Synaptobrevin Gly-rich_Ago1 PF12764.2 EGG01225.1 - 0.15 12.6 3.4 11 6.7 0.0 2.8 3 0 0 3 3 3 0 Glycine-rich region of argonaut DUF1664 PF07889.7 EGG01225.1 - 0.3 10.9 4.0 0.25 11.1 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3552 PF12072.3 EGG01225.1 - 9.2 5.4 12.3 1.1 8.3 1.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) ABC2_membrane PF01061.19 EGG01226.1 - 3.5e-79 264.8 58.7 2.8e-41 140.9 20.0 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EGG01226.1 - 3.7e-33 114.7 0.0 1.4e-15 57.7 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EGG01226.1 - 4.5e-30 103.3 9.2 1.4e-23 82.5 0.0 3.7 4 0 0 4 4 3 2 CDR ABC transporter AAA_25 PF13481.1 EGG01226.1 - 1.1e-06 28.1 0.2 0.0056 16.1 0.1 2.7 3 0 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 EGG01226.1 - 4e-06 26.1 11.6 4e-06 26.1 8.0 3.2 2 1 1 3 3 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EGG01226.1 - 0.00049 20.1 0.1 0.13 12.1 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EGG01226.1 - 0.0008 18.8 0.1 0.0077 15.7 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGG01226.1 - 0.0018 17.5 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGG01226.1 - 0.0027 17.6 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EGG01226.1 - 0.0037 17.2 0.0 0.0084 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EGG01226.1 - 0.0073 15.5 0.0 0.25 10.5 0.0 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EGG01226.1 - 0.016 15.1 0.1 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGG01226.1 - 0.035 13.9 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EGG01226.1 - 0.045 13.2 0.5 0.076 12.4 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EGG01226.1 - 0.055 13.6 0.6 0.3 11.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EGG01226.1 - 0.073 12.0 0.0 2.8 6.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EGG01226.1 - 0.083 13.1 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGG01226.1 - 0.093 13.5 0.0 0.46 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGG01226.1 - 0.11 11.9 0.1 13 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain ABC_trans_N PF14510.1 EGG01226.1 - 0.23 11.5 0.0 0.58 10.2 0.0 1.7 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal AAA_23 PF13476.1 EGG01226.1 - 0.38 11.0 0.1 0.85 9.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Voldacs PF03517.8 EGG01229.1 - 6.1e-29 100.5 0.1 7.8e-29 100.2 0.1 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Response_reg PF00072.19 EGG01232.1 - 1.5e-19 70.0 0.1 3.8e-19 68.7 0.1 1.7 1 1 0 1 1 1 1 Response regulator receiver domain DUF2673 PF10880.3 EGG01232.1 - 0.11 12.5 0.5 2.4 8.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) 60KD_IMP PF02096.15 EGG01233.1 - 0.11 12.1 0.9 0.13 11.9 0.3 1.3 1 1 0 1 1 1 0 60Kd inner membrane protein Peptidase_M24 PF00557.19 EGG01235.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M24 ADIP PF11559.3 EGG01237.1 - 7.7e-08 32.3 16.7 7.7e-08 32.3 11.6 3.2 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding ERM PF00769.14 EGG01237.1 - 0.00012 21.6 7.8 0.00012 21.6 5.4 2.6 2 1 0 2 2 2 1 Ezrin/radixin/moesin family Carb_kinase PF01256.12 EGG01238.1 - 6e-54 182.8 0.0 9.1e-54 182.2 0.0 1.3 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EGG01238.1 - 0.0043 16.2 0.0 0.015 14.5 0.0 1.7 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DUF1769 PF08588.5 EGG01241.1 - 5.3e-21 74.3 0.2 1.4e-20 73.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Trehalose_PPase PF02358.11 EGG01242.1 - 3.8e-05 22.7 0.0 0.0058 15.5 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase Sec23_trunk PF04811.10 EGG01243.1 - 2.8e-58 197.1 0.0 4.2e-58 196.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGG01243.1 - 1.6e-25 88.4 0.1 2.7e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGG01243.1 - 5.8e-17 61.9 0.0 1.2e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGG01243.1 - 2.8e-15 55.5 0.7 2.8e-15 55.5 0.5 2.2 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGG01243.1 - 1.6e-05 24.4 0.0 3.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat RCC1_2 PF13540.1 EGG01244.1 - 1.1e-21 75.8 18.7 7.5e-07 28.6 0.3 6.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EGG01244.1 - 8.7e-16 57.8 5.4 0.043 14.0 0.8 7.7 8 2 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EGG01244.1 - 3.6e-05 23.3 0.6 0.00011 21.8 0.4 1.9 1 0 0 1 1 1 1 F-box-like Methyltransf_6 PF03737.10 EGG01245.1 - 3.9e-27 95.0 0.7 2.5e-25 89.1 0.5 2.1 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase CDC45 PF02724.9 EGG01247.1 - 0.95 7.4 5.9 1 7.3 4.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGG01247.1 - 3.1 5.5 10.8 3.2 5.5 7.5 1.0 1 0 0 1 1 1 0 Nop14-like family PWI PF01480.12 EGG01248.1 - 1.2e-26 92.6 0.0 1.9e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 PWI domain DUF1003 PF06210.6 EGG01248.1 - 0.0022 17.8 0.1 0.0055 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1003) RF-1 PF00472.15 EGG01250.1 - 1.4e-12 47.4 0.3 2.4e-12 46.6 0.2 1.5 1 1 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EGG01250.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 PCRF domain Zn_Tnp_IS1595 PF12760.2 EGG01250.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain LIM PF00412.17 EGG01253.1 - 4.5 7.4 11.2 0.36 10.9 2.2 2.3 1 1 1 2 2 2 0 LIM domain Ndc1_Nup PF09531.5 EGG01257.1 - 2.6 6.3 21.6 4.6 5.5 14.9 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup V_ATPase_I PF01496.14 EGG01257.1 - 6.2 4.5 9.0 8.6 4.0 6.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sel1 PF08238.7 EGG01258.1 - 1.2e-40 137.0 18.6 2.4e-07 31.1 0.3 8.1 9 0 0 9 9 9 7 Sel1 repeat DUF4244 PF14029.1 EGG01258.1 - 0.14 11.2 2.0 0.46 9.6 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) Arc_PepC PF06819.6 EGG01258.1 - 0.19 11.6 0.2 1.4 8.9 0.1 2.1 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain DUF2650 PF10853.3 EGG01258.1 - 0.36 10.3 0.0 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) TPR_11 PF13414.1 EGG01258.1 - 0.77 9.4 9.5 0.54 9.9 0.3 3.5 2 1 0 3 3 3 0 TPR repeat Nop14 PF04147.7 EGG01259.1 - 0.058 11.3 15.2 0.055 11.4 10.5 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 EGG01259.1 - 0.11 11.5 9.4 0.1 11.6 6.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.11 EGG01259.1 - 0.68 8.8 7.3 0.71 8.8 5.1 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 EGG01259.1 - 8.4 5.6 8.8 9.7 5.4 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pkinase PF00069.20 EGG01260.1 - 7.3e-69 231.8 0.0 1.5e-68 230.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG01260.1 - 3.5e-49 167.1 0.0 7.2e-49 166.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG01260.1 - 2.1e-05 23.6 0.0 0.0011 17.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like CCAP PF11105.3 EGG01260.1 - 0.077 12.7 2.0 0.19 11.4 0.5 2.2 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a DNA_methylase PF00145.12 EGG01261.1 - 5.3e-18 65.2 1.1 1.7e-17 63.5 0.0 2.4 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase SNF2_N PF00176.18 EGG01261.1 - 8.5e-18 64.1 0.1 1.2e-13 50.5 0.0 2.8 2 0 0 2 2 2 2 SNF2 family N-terminal domain Cyclin_C PF02984.14 EGG01263.1 - 0.0011 18.8 0.1 0.0017 18.2 0.1 1.6 1 1 0 1 1 1 1 Cyclin, C-terminal domain ATP-synt_S1 PF05827.7 EGG01263.1 - 0.096 11.9 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) zf-H2C2_2 PF13465.1 EGG01265.1 - 1.9e-05 24.6 7.0 7.2e-05 22.8 4.8 2.0 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGG01265.1 - 0.00063 19.9 8.4 0.089 13.1 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG01265.1 - 0.00079 19.5 10.7 0.073 13.4 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGG01265.1 - 0.016 15.0 1.1 0.033 14.0 0.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger CSTF2_hinge PF14327.1 EGG01266.1 - 5.3e-28 96.9 2.5 5.3e-28 96.9 1.8 2.3 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EGG01266.1 - 6.4e-17 60.9 0.0 1.2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EGG01266.1 - 6.4e-11 41.3 7.2 6.4e-11 41.3 5.0 2.1 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_6 PF14259.1 EGG01266.1 - 2.1e-09 37.2 0.0 4.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG01266.1 - 7.2e-06 25.7 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 EGG01266.1 - 7.2 5.9 13.6 8.8 5.6 9.4 1.2 1 0 0 1 1 1 0 Vta1 like Daxx PF03344.10 EGG01267.1 - 0.17 10.3 11.6 0.29 9.5 8.0 1.3 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EGG01267.1 - 1.1 7.1 5.6 1.4 6.8 3.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DPM3 PF08285.6 EGG01268.1 - 0.09 12.6 0.7 5.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Parathyroid PF01279.12 EGG01268.1 - 2 9.1 6.2 11 6.6 2.9 3.0 2 1 0 2 2 2 0 Parathyroid hormone family DUF2934 PF11154.3 EGG01268.1 - 7.6 5.9 10.3 3.5 7.0 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) BING4CT PF08149.6 EGG01269.1 - 3.1e-22 77.8 1.1 4.1e-22 77.4 0.0 1.7 2 0 0 2 2 2 1 BING4CT (NUC141) domain Myb_DNA-binding PF00249.26 EGG01270.1 - 1.7e-10 40.7 0.0 5.4e-10 39.1 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EGG01270.1 - 2.8e-07 29.9 7.8 3.3e-05 23.3 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 EGG01270.1 - 0.00013 21.9 0.1 0.00033 20.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SHOCT PF09851.4 EGG01270.1 - 0.096 12.1 2.5 0.37 10.3 0.3 2.8 3 0 0 3 3 3 0 Short C-terminal domain PHD PF00628.24 EGG01272.1 - 9.8e-10 37.9 8.6 1.8e-09 37.1 5.9 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EGG01272.1 - 0.0028 18.0 0.1 0.0028 18.0 0.1 5.1 5 2 1 6 6 6 1 SET domain PHD_2 PF13831.1 EGG01272.1 - 0.0048 16.1 4.7 0.0088 15.3 3.3 1.4 1 0 0 1 1 1 1 PHD-finger Ribonuc_L-PSP PF01042.16 EGG01276.1 - 6.5e-44 148.5 0.1 7.4e-44 148.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Rab3-GTPase_cat PF13890.1 EGG01276.1 - 0.068 12.5 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Exo_endo_phos PF03372.18 EGG01278.1 - 2.8e-14 53.6 0.1 4e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGEF PF00621.15 EGG01281.1 - 2e-36 125.5 0.5 3.4e-36 124.7 0.4 1.4 1 0 0 1 1 1 1 RhoGEF domain EF-hand_4 PF12763.2 EGG01281.1 - 7.3e-14 51.3 0.0 2.5e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_9 PF14604.1 EGG01281.1 - 5e-13 48.3 0.3 4.2e-05 23.0 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EGG01281.1 - 1.6e-09 36.9 1.0 2.2e-05 23.7 0.0 2.7 2 0 0 2 2 2 2 SH3 domain DUF1720 PF08226.6 EGG01281.1 - 2.2e-07 30.8 36.5 2.2e-07 30.8 25.3 5.7 2 1 1 3 3 3 1 Domain of unknown function (DUF1720) WH2 PF02205.15 EGG01281.1 - 5e-07 29.1 0.2 9.9e-07 28.1 0.1 1.5 1 0 0 1 1 1 1 WH2 motif SH3_2 PF07653.12 EGG01281.1 - 3.5e-05 23.2 0.0 0.097 12.1 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain EF-hand_7 PF13499.1 EGG01281.1 - 0.0036 17.4 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair Glyco_hydro_43 PF04616.9 EGG01282.1 - 7.1e-37 127.0 2.4 1.3e-36 126.1 1.6 1.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 CW_binding_1 PF01473.15 EGG01282.1 - 1.2 9.3 5.1 5.8 7.2 0.2 3.5 3 0 0 3 3 3 0 Putative cell wall binding repeat Spc24 PF08286.6 EGG01283.1 - 0.0059 16.3 0.3 0.0085 15.7 0.2 1.2 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 Methyltransf_16 PF10294.4 EGG01283.1 - 0.094 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Ribosomal_L23eN PF03939.8 EGG01284.1 - 3.1e-20 71.9 17.4 1e-19 70.2 12.1 2.0 1 1 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EGG01284.1 - 5.1e-16 58.3 0.5 5.1e-16 58.3 0.3 2.2 2 0 0 2 2 2 1 Ribosomal protein L23 Pea-VEAacid PF08111.6 EGG01285.1 - 0.036 14.1 1.7 9 6.6 0.2 3.2 3 0 0 3 3 3 0 Pea-VEAacid family Ribosomal_L6e PF01159.14 EGG01286.1 - 8.6e-37 125.6 0.4 1.1e-36 125.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L6e AAA_17 PF13207.1 EGG01287.1 - 0.026 15.3 0.0 0.2 12.5 0.0 2.1 1 1 0 2 2 2 0 AAA domain Acyl_transf_3 PF01757.17 EGG01288.1 - 3.3e-27 95.2 23.6 4.6e-27 94.7 16.4 1.2 1 0 0 1 1 1 1 Acyltransferase family Peptidase_M16 PF00675.15 EGG01293.1 - 1.2e-47 161.3 0.1 2.5e-47 160.3 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGG01293.1 - 1e-38 132.8 0.0 3.5e-37 127.8 0.0 2.4 2 0 0 2 2 2 1 Peptidase M16 inactive domain EF-hand_7 PF13499.1 EGG01294.1 - 2e-11 43.8 0.2 5.3e-06 26.4 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGG01294.1 - 5.3e-11 41.4 1.9 4.1e-05 23.1 0.0 3.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EGG01294.1 - 6.8e-11 40.6 1.5 5e-06 25.4 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 EGG01294.1 - 0.021 14.1 1.8 0.087 12.2 0.1 2.3 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 EGG01294.1 - 0.039 13.5 4.8 0.31 10.6 0.3 3.0 2 1 1 3 3 3 0 EF-hand domain pair AAA PF00004.24 EGG01295.1 - 1.7e-37 128.6 0.0 3.1e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGG01295.1 - 5.8e-07 28.8 0.1 2.3e-06 26.8 0.0 2.0 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGG01295.1 - 1e-06 28.6 0.0 2.6e-06 27.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EGG01295.1 - 1.9e-06 28.0 0.2 9.8e-05 22.5 0.1 2.6 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EGG01295.1 - 4.2e-06 26.5 0.3 0.00017 21.2 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGG01295.1 - 6.1e-06 26.3 0.1 0.00031 20.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EGG01295.1 - 4.3e-05 22.6 0.0 6.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EGG01295.1 - 0.00013 22.0 0.0 0.0016 18.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 EGG01295.1 - 0.00013 21.8 0.0 0.00038 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 EGG01295.1 - 0.00019 21.5 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 EGG01295.1 - 0.00024 20.9 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EGG01295.1 - 0.00037 20.1 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG01295.1 - 0.00051 20.8 0.0 0.0012 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGG01295.1 - 0.00084 18.5 0.5 0.0016 17.6 0.1 1.5 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EGG01295.1 - 0.0011 18.2 0.0 0.14 11.2 0.0 2.3 1 1 1 2 2 2 1 KaiC AAA_18 PF13238.1 EGG01295.1 - 0.0011 19.2 0.1 0.0034 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGG01295.1 - 0.0016 17.9 0.2 0.07 12.5 0.1 2.2 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.10 EGG01295.1 - 0.0017 17.1 0.0 0.0027 16.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 EGG01295.1 - 0.004 16.8 0.2 0.0094 15.6 0.1 1.6 2 0 0 2 2 1 1 NACHT domain ABC_tran PF00005.22 EGG01295.1 - 0.0094 16.2 0.0 0.023 15.0 0.0 1.8 1 1 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.12 EGG01295.1 - 0.01 15.2 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 EGG01295.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 EGG01295.1 - 0.011 14.5 0.3 0.019 13.6 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus AAA_28 PF13521.1 EGG01295.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain tRNA_lig_kinase PF08303.6 EGG01295.1 - 0.016 15.0 0.0 0.057 13.2 0.0 1.8 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_3 PF07726.6 EGG01295.1 - 0.019 14.5 0.0 0.049 13.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGG01295.1 - 0.024 14.3 0.1 0.13 11.9 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 EGG01295.1 - 0.037 13.4 0.0 0.11 11.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EGG01295.1 - 0.05 12.4 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EGG01295.1 - 0.065 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 EGG01295.1 - 0.089 12.4 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_21 PF13304.1 EGG01295.1 - 0.096 12.6 1.6 2.1 8.2 0.1 2.8 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.1 EGG01295.1 - 0.11 12.2 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain HSF_DNA-bind PF00447.12 EGG01296.1 - 3.9e-24 84.7 0.0 5.9e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding GlutR_dimer PF00745.15 EGG01298.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain PRELI PF04707.9 EGG01300.1 - 8.9e-34 116.3 0.0 2.4e-33 114.9 0.0 1.6 1 1 0 1 1 1 1 PRELI-like family MU117 PF15474.1 EGG01301.1 - 0.073 13.5 1.0 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 Meiotically up-regulated gene family Jnk-SapK_ap_N PF09744.4 EGG01302.1 - 0.0013 18.7 1.5 0.0023 17.9 1.0 1.5 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 MutS_V PF00488.16 EGG01303.1 - 2.5e-25 89.2 0.2 2.7e-25 89.1 0.1 1.0 1 0 0 1 1 1 1 MutS domain V MitMem_reg PF13012.1 EGG01307.1 - 0.029 14.4 0.4 0.061 13.4 0.2 1.6 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF615 PF04751.9 EGG01310.1 - 0.04 13.5 2.4 0.053 13.1 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF615) DUF2951 PF11166.3 EGG01310.1 - 0.071 12.9 2.3 0.12 12.1 1.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Peptidase_M16 PF00675.15 EGG01311.1 - 5.9e-39 133.1 0.0 1.3e-38 132.0 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGG01311.1 - 1.4e-16 60.6 0.1 4.3e-16 59.1 0.0 1.8 2 1 0 2 2 2 1 Peptidase M16 inactive domain Cathelicidins PF00666.12 EGG01311.1 - 0.091 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Cathelicidin DUF816 PF05674.7 EGG01312.1 - 0.0067 16.1 1.3 0.0067 16.1 0.9 1.5 1 1 1 2 2 2 1 Baculovirus protein of unknown function (DUF816) BAF1_ABF1 PF04684.8 EGG01312.1 - 2.1 7.1 8.0 2.5 6.8 5.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SOG2 PF10428.4 EGG01314.1 - 1.7 7.2 10.0 1.9 7.0 6.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4605 PF15378.1 EGG01315.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) PolyG_pol PF01518.11 EGG01317.1 - 0.025 13.0 0.1 0.029 12.8 0.1 1.1 1 0 0 1 1 1 0 Sigma NS protein CDK5_activator PF03261.10 EGG01318.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein MU117 PF15474.1 EGG01322.1 - 0.0045 17.4 0.3 0.0061 17.0 0.2 1.1 1 0 0 1 1 1 1 Meiotically up-regulated gene family ER_lumen_recept PF00810.13 EGG01323.1 - 7.6e-58 195.1 12.2 1.1e-57 194.7 8.4 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EGG01323.1 - 0.0091 15.5 12.2 0.43 10.1 0.1 4.3 5 0 0 5 5 5 2 PQ loop repeat DAHP_synth_2 PF01474.11 EGG01324.1 - 1.1e-163 544.7 0.0 1.3e-163 544.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Hpt PF01627.18 EGG01325.1 - 1.4e-08 34.6 0.0 2.5e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Hpt domain HIT PF01230.18 EGG01326.1 - 9.7e-24 83.7 0.9 1.3e-23 83.3 0.7 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGG01326.1 - 8.4e-13 48.5 0.6 1.3e-12 47.9 0.4 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGG01326.1 - 0.00018 21.1 0.1 0.00024 20.7 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RNA_pol_Rpb6 PF01192.17 EGG01328.1 - 7.2e-21 73.7 0.1 8.3e-21 73.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 Herpes_capsid PF06112.6 EGG01329.1 - 0.78 9.7 17.4 0.13 12.2 3.1 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Cpn60_TCP1 PF00118.19 EGG01330.1 - 2e-147 491.7 0.6 2.3e-147 491.5 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Piwi PF02171.12 EGG01332.1 - 5.5e-79 265.2 0.0 8e-79 264.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EGG01332.1 - 3.7e-10 39.2 0.0 8e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EGG01332.1 - 1.3e-06 27.7 0.0 3.2e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Glycos_trans_3N PF02885.12 EGG01334.1 - 0.096 12.2 0.3 0.22 11.1 0.2 1.5 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain DUF1515 PF07439.6 EGG01336.1 - 0.04 13.7 0.6 0.083 12.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) HMG_box PF00505.14 EGG01336.1 - 0.04 14.1 2.7 6.8 7.0 0.1 3.1 3 0 0 3 3 3 0 HMG (high mobility group) box FancD2 PF14631.1 EGG01336.1 - 1.2 6.1 6.2 2.3 5.2 4.3 1.3 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease FAM176 PF14851.1 EGG01336.1 - 3.7 7.2 5.9 7.8 6.1 3.6 1.9 2 0 0 2 2 2 0 FAM176 family Soyouz_module PF14313.1 EGG01337.1 - 0.35 10.4 5.0 1.1 8.8 1.1 2.5 1 1 1 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) OGFr_N PF04664.8 EGG01338.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region Mob1_phocein PF03637.12 EGG01339.1 - 1.5e-31 109.4 0.8 3.2e-31 108.3 0.1 1.8 2 0 0 2 2 2 1 Mob1/phocein family ANAPC15 PF15243.1 EGG01339.1 - 0.0014 18.6 5.6 0.0026 17.7 3.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 CDC45 PF02724.9 EGG01339.1 - 3.5 5.5 7.5 4.2 5.2 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L36e PF01158.13 EGG01342.1 - 2.2e-38 130.1 2.3 2.5e-38 129.9 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EGG01342.1 - 0.12 11.4 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 LemA family Pkinase PF00069.20 EGG01344.1 - 7.3e-67 225.2 0.0 9.4e-67 224.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG01344.1 - 1.1e-41 142.5 0.0 3.2e-41 141.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG01344.1 - 2.2e-07 30.1 0.0 3.2e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGG01344.1 - 0.00089 18.3 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGG01344.1 - 0.057 13.1 0.1 0.19 11.4 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RPAP1_N PF08621.5 EGG01345.1 - 0.046 13.3 0.1 0.09 12.3 0.1 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal DUF1033 PF06279.6 EGG01346.1 - 0.089 12.6 0.2 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) BaffR-Tall_bind PF09256.5 EGG01347.1 - 0.12 11.9 1.5 2.6 7.7 0.1 2.3 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding zf-C2H2_4 PF13894.1 EGG01347.1 - 0.99 9.8 7.1 2.5 8.6 2.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1970 PF09301.5 EGG01350.1 - 0.042 13.8 0.8 0.042 13.8 0.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) S-AdoMet_synt_C PF02773.11 EGG01351.1 - 2.5e-73 244.3 0.2 4.6e-73 243.4 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EGG01351.1 - 2.8e-47 159.5 0.0 4.8e-47 158.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EGG01351.1 - 3e-42 142.9 0.0 7.2e-42 141.6 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain SIP1 PF04938.7 EGG01352.1 - 4.6e-16 58.8 0.0 1.7e-15 57.0 0.0 1.8 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF4386 PF14329.1 EGG01352.1 - 0.025 14.0 0.1 0.047 13.1 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4386) DUF3226 PF11536.3 EGG01353.1 - 0.0071 15.8 2.4 0.011 15.1 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) IncA PF04156.9 EGG01353.1 - 0.055 13.0 4.0 0.11 12.0 2.8 1.6 1 0 0 1 1 1 0 IncA protein SURF6 PF04935.7 EGG01353.1 - 0.088 12.0 8.0 0.021 14.0 3.1 1.7 2 0 0 2 2 2 0 Surfeit locus protein 6 Bcr-Abl_Oligo PF09036.5 EGG01353.1 - 0.11 12.4 0.8 0.27 11.1 0.1 1.9 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF489 PF04356.7 EGG01353.1 - 0.39 10.2 4.3 0.53 9.8 2.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF489) Mannosyl_trans PF05007.8 EGG01354.1 - 4.7e-74 249.3 24.3 7.4e-74 248.6 16.9 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EGG01354.1 - 5.6e-07 28.7 33.5 7.7e-07 28.2 22.8 1.6 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EGG01354.1 - 1.2e-05 24.9 1.9 1.2e-05 24.9 1.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2029) R3H-assoc PF13902.1 EGG01355.1 - 0.0063 16.4 0.1 0.019 14.8 0.1 1.9 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 EGG01355.1 - 0.017 14.7 0.0 0.057 13.1 0.0 1.9 1 0 0 1 1 1 0 R3H domain 2OG-FeII_Oxy_2 PF13532.1 EGG01356.1 - 4e-08 33.3 0.0 2.5e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIG-Y PF15159.1 EGG01357.1 - 0.016 15.4 0.8 0.043 14.0 0.3 1.9 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF4345 PF14248.1 EGG01357.1 - 0.019 14.4 0.1 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) ATP-synt_E PF05680.7 EGG01358.1 - 4.7e-16 58.5 0.0 4.9e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 ATP synthase E chain Orbi_NS3 PF01616.11 EGG01358.1 - 0.019 13.9 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Orbivirus NS3 Cation_efflux PF01545.16 EGG01359.1 - 5.9e-79 265.1 6.3 7.5e-79 264.7 4.3 1.1 1 0 0 1 1 1 1 Cation efflux family zf-H2C2_2 PF13465.1 EGG01360.1 - 2.3e-05 24.4 7.0 8.3e-05 22.6 4.8 2.0 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGG01360.1 - 0.00078 19.6 8.4 0.1 12.9 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG01360.1 - 0.00099 19.2 10.7 0.084 13.2 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGG01360.1 - 0.022 14.6 1.9 0.076 12.9 1.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Cytochrom_B559a PF00284.15 EGG01361.1 - 0.0044 16.4 0.1 0.037 13.5 0.1 2.0 1 1 1 2 2 2 1 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Plasmodium_HRP PF05403.6 EGG01361.1 - 0.092 12.3 28.5 0.1 12.1 19.8 1.1 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) FAT PF02259.18 EGG01362.1 - 2.1e-117 392.0 4.7 2.1e-117 392.0 3.3 1.7 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EGG01362.1 - 9.4e-55 185.6 0.6 1.9e-54 184.6 0.4 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EGG01362.1 - 6.6e-44 149.6 0.5 1.8e-41 141.7 0.0 4.8 4 1 0 5 5 5 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EGG01362.1 - 6.8e-40 135.2 0.6 6.3e-39 132.0 0.0 3.1 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 EGG01362.1 - 1.9e-18 66.5 20.4 0.00026 21.2 0.0 9.4 8 1 4 12 12 12 6 HEAT repeats FATC PF02260.15 EGG01362.1 - 2.5e-15 55.5 0.8 8.4e-15 53.9 0.1 2.3 2 0 0 2 2 2 1 FATC domain HEAT PF02985.17 EGG01362.1 - 4.9e-12 44.8 17.7 0.76 10.0 0.0 10.6 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 EGG01362.1 - 1.1e-07 32.0 25.5 0.012 16.0 0.0 11.1 9 2 4 13 13 13 3 HEAT-like repeat UME PF08064.8 EGG01362.1 - 0.0075 16.2 11.2 4.3 7.3 0.0 6.9 7 2 1 8 8 8 1 UME (NUC010) domain zf-UBR PF02207.15 EGG01366.1 - 0.0038 16.9 4.5 0.0073 16.0 3.1 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) FYVE_2 PF02318.11 EGG01366.1 - 0.2 11.5 2.0 0.49 10.3 1.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger C1_3 PF07649.7 EGG01366.1 - 0.27 11.2 1.5 0.56 10.3 1.0 1.5 1 0 0 1 1 1 0 C1-like domain DUF3716 PF12511.3 EGG01366.1 - 0.29 10.7 3.7 0.27 10.8 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Tnp_zf-ribbon_2 PF13842.1 EGG01366.1 - 2.3 8.7 5.5 15 6.1 3.8 2.3 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon WD40 PF00400.27 EGG01367.1 - 8.3e-35 117.4 16.5 1.4e-07 31.1 0.2 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGG01367.1 - 3.8e-27 93.9 0.7 7.3e-27 93.0 0.5 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EGG01367.1 - 0.00033 20.4 0.2 0.0012 18.5 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Herpes_capsid PF06112.6 EGG01368.1 - 0.05 13.6 10.8 0.043 13.8 6.4 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DUF1062 PF06353.7 EGG01370.1 - 0.037 14.2 6.9 0.051 13.8 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) ArfGap PF01412.13 EGG01370.1 - 0.63 9.8 8.1 0.43 10.3 3.3 2.0 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Salp15 PF12115.3 EGG01370.1 - 2.4 8.4 5.3 3.3 7.9 3.7 1.5 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF1451 PF07295.6 EGG01370.1 - 7.5 6.3 11.0 8.4 6.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) Amidase PF01425.16 EGG01371.1 - 7.4e-94 315.0 0.0 9.3e-94 314.7 0.0 1.1 1 0 0 1 1 1 1 Amidase F-box-like PF12937.2 EGG01372.1 - 0.00011 21.8 0.0 0.00036 20.1 0.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EGG01372.1 - 0.17 11.5 2.0 2.4 7.8 1.5 2.9 2 1 0 2 2 2 0 F-box domain Ribosomal_S10 PF00338.17 EGG01374.1 - 6.6e-18 64.3 0.0 7.2e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Alpha_kinase PF02816.13 EGG01376.1 - 1.1e-07 31.7 0.0 1.7e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family TPMT PF05724.6 EGG01379.1 - 3.9e-34 118.0 0.0 4.4e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 EGG01379.1 - 2e-08 33.9 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG01379.1 - 2e-06 28.3 0.0 3.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG01379.1 - 2.3e-06 28.0 0.0 3.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG01379.1 - 5.5e-06 26.7 0.0 7.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG01379.1 - 5.5e-05 23.4 0.0 7.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGG01379.1 - 0.0037 16.4 0.0 0.0047 16.1 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 EGG01379.1 - 0.0041 17.1 0.0 0.0051 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG01379.1 - 0.032 13.9 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 EGG01380.1 - 1.3e-07 31.2 1.1 0.13 12.1 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Abhydrolase_6 PF12697.2 EGG01384.1 - 3.4e-05 23.8 0.0 4.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG01384.1 - 0.00032 20.4 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 EGG01384.1 - 0.0025 17.1 0.4 0.018 14.3 0.3 2.0 1 1 0 1 1 1 1 Lipase (class 2) LCAT PF02450.10 EGG01384.1 - 0.0045 16.0 0.0 0.0065 15.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EGG01384.1 - 0.0065 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EGG01384.1 - 0.016 14.4 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EGG01385.1 - 2.5e-07 30.8 0.0 2.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG01385.1 - 1.3e-06 28.1 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 EGG01385.1 - 0.00028 20.2 0.1 0.0011 18.3 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 2) DUF900 PF05990.7 EGG01385.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 EGG01385.1 - 0.038 12.9 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EGG01385.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) 3HCDH_N PF02737.13 EGG01390.1 - 1.2e-56 191.2 0.2 1.8e-56 190.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EGG01390.1 - 1.8e-32 111.6 0.0 4e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGG01390.1 - 0.00025 20.9 1.9 0.0063 16.3 1.3 2.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EGG01390.1 - 0.006 16.1 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EGG01390.1 - 0.012 15.9 0.0 0.11 12.7 0.0 2.1 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EGG01390.1 - 0.041 14.2 0.4 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGG01390.1 - 0.18 10.6 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AMP-binding PF00501.23 EGG01391.1 - 2.2e-93 312.9 0.0 2.7e-93 312.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGG01391.1 - 3.5e-06 27.8 0.0 8.6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cullin PF00888.17 EGG01393.1 - 3.1e-180 600.5 13.6 3.1e-180 600.5 9.4 1.4 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGG01393.1 - 1e-27 95.7 2.7 1e-27 95.7 1.9 2.4 3 0 0 3 3 3 1 Cullin protein neddylation domain HTH_27 PF13463.1 EGG01393.1 - 0.0047 17.2 0.4 1.9 8.8 0.0 3.4 3 0 0 3 3 3 1 Winged helix DNA-binding domain MarR_2 PF12802.2 EGG01393.1 - 0.16 11.6 0.3 14 5.4 0.0 3.1 4 0 0 4 4 4 0 MarR family Kinesin PF00225.18 EGG01395.1 - 3.4e-80 269.2 0.0 4.2e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Metallophos_2 PF12850.2 EGG01396.1 - 6e-09 35.9 0.0 1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGG01396.1 - 5.9e-08 32.3 0.6 5.9e-08 32.3 0.4 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Exo_endo_phos_2 PF14529.1 EGG01396.1 - 0.066 12.8 0.1 0.21 11.1 0.1 1.9 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Methyltransf_23 PF13489.1 EGG01396.1 - 0.11 12.2 0.5 0.29 10.8 0.2 1.9 2 0 0 2 2 2 0 Methyltransferase domain ThiF PF00899.16 EGG01398.1 - 2.5e-33 114.7 0.0 3.5e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EGG01398.1 - 2.4e-20 71.8 0.1 4.6e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 EGG01398.1 - 8.8e-05 22.6 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EGG01398.1 - 0.0061 15.4 0.5 0.0089 14.9 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Saccharop_dh PF03435.13 EGG01398.1 - 0.016 14.2 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGG01398.1 - 0.034 13.5 0.2 0.053 12.8 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EGG01398.1 - 0.043 14.0 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 EGG01398.1 - 0.11 12.3 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Arf PF00025.16 EGG01399.1 - 1.1e-43 148.4 0.0 1.3e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGG01399.1 - 1e-19 70.4 0.0 1.2e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG01399.1 - 3.6e-12 46.8 0.0 1e-11 45.3 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EGG01399.1 - 1.8e-09 37.0 0.0 2.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGG01399.1 - 5.4e-08 32.2 0.0 8.3e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGG01399.1 - 2.5e-07 30.6 0.0 4.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGG01399.1 - 1.8e-06 26.9 0.9 7.8e-06 24.8 0.1 2.1 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 EGG01399.1 - 1.5e-05 24.5 0.0 0.00051 19.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGG01399.1 - 0.00029 20.6 0.1 0.033 13.9 0.3 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 EGG01399.1 - 0.0065 15.7 1.1 0.034 13.4 0.8 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EGG01399.1 - 0.081 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_S30AE PF02482.14 EGG01401.1 - 0.63 10.5 16.9 0.18 12.2 8.3 2.2 1 1 1 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Peptidase_S46 PF10459.4 EGG01401.1 - 1.1 7.6 17.3 1.4 7.2 12.0 1.1 1 0 0 1 1 1 0 Peptidase S46 SUV3_C PF12513.3 EGG01401.1 - 1.5 8.3 4.3 18 4.8 0.1 2.8 2 1 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal PLRV_ORF5 PF01690.12 EGG01401.1 - 5.3 6.0 11.9 7.5 5.5 8.3 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF2009 PF09418.5 EGG01401.1 - 8.9 4.9 11.1 4 6.1 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2009) Glyco_hydro_7 PF00840.15 EGG01404.1 - 8.4e-196 650.4 13.8 1e-195 650.2 9.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_7 PF00840.15 EGG01405.1 - 2.5e-193 642.3 15.5 3e-193 642.0 10.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DOT1 PF08123.8 EGG01406.1 - 0.0019 17.5 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 zf-H2C2 PF09337.5 EGG01406.1 - 0.032 13.6 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Na_H_Exchanger PF00999.16 EGG01407.1 - 5.3e-57 193.0 30.9 6.7e-57 192.7 21.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3529 PF12046.3 EGG01407.1 - 1.4 7.9 3.8 3.7 6.5 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3529) tRNA_anti-codon PF01336.20 EGG01409.1 - 0.053 13.3 0.0 6.9 6.6 0.0 2.8 2 1 0 2 2 2 0 OB-fold nucleic acid binding domain SH3_1 PF00018.23 EGG01412.1 - 3e-10 39.2 0.3 5e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGG01412.1 - 5.9e-07 28.9 0.1 9.9e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGG01412.1 - 6.6e-07 28.7 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain ecTbetaR2 PF08917.5 EGG01414.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain Spindle_Spc25 PF08234.7 EGG01419.1 - 2.5e-19 69.0 2.0 6e-19 67.8 0.7 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 AAA_13 PF13166.1 EGG01419.1 - 0.0004 19.0 8.4 0.00051 18.6 5.8 1.1 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.6 EGG01419.1 - 0.029 13.0 12.7 0.044 12.4 8.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4471 PF14740.1 EGG01419.1 - 0.057 12.6 2.1 0.089 12.0 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) OmpH PF03938.9 EGG01419.1 - 2 8.3 12.7 3.3 7.6 8.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sec8_exocyst PF04048.9 EGG01419.1 - 2.4 7.7 11.7 17 4.9 0.0 2.6 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain V_ATPase_I PF01496.14 EGG01419.1 - 4.5 5.0 9.7 5.8 4.6 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DOT1 PF08123.8 EGG01420.1 - 4.7e-56 189.3 0.0 6.9e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 EGG01420.1 - 0.066 12.7 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGG01420.1 - 0.083 13.4 0.0 0.22 12.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DUF4551 PF15087.1 EGG01420.1 - 3.8 5.7 10.8 5.6 5.2 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Glyco_hydro_10 PF00331.15 EGG01421.1 - 0.00015 20.9 0.0 0.00015 20.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_trans_1_4 PF13692.1 EGG01422.1 - 1.4e-20 73.7 0.0 3.5e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EGG01422.1 - 5.4e-09 35.6 0.0 9.1e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGG01422.1 - 2.9e-05 24.2 0.1 4.7e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EGG01422.1 - 0.00016 21.9 0.0 0.00035 20.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 RRM_1 PF00076.17 EGG01423.1 - 7e-85 278.6 0.6 2.2e-21 75.2 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG01423.1 - 7.9e-54 179.5 0.1 1.6e-14 53.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG01423.1 - 1e-41 140.5 0.2 1.6e-09 37.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EGG01423.1 - 2e-29 101.0 1.2 4.2e-29 100.0 0.8 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 EGG01423.1 - 0.00022 21.0 1.4 0.27 11.0 0.1 4.0 4 0 0 4 4 4 1 RNA binding motif Limkain-b1 PF11608.3 EGG01423.1 - 0.0012 18.5 0.7 0.91 9.3 0.0 3.9 4 0 0 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.1 EGG01423.1 - 0.0076 16.0 0.2 17 5.3 0.0 4.0 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif Trypsin_2 PF13365.1 EGG01424.1 - 9e-09 35.3 0.0 1.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EGG01424.1 - 0.00029 20.4 0.0 0.00063 19.3 0.0 1.5 1 1 0 1 1 1 1 Trypsin Peptidase_S29 PF02907.10 EGG01424.1 - 0.014 14.8 0.0 0.038 13.5 0.0 1.6 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Peptidase_S7 PF00949.16 EGG01424.1 - 0.13 11.6 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease PCI PF01399.22 EGG01426.1 - 1.1e-06 28.8 0.1 3.2e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 PCI domain DUF3646 PF12362.3 EGG01426.1 - 0.0021 17.9 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III gamma and tau subunits C terminal BORG_CEP PF14957.1 EGG01426.1 - 0.69 10.8 0.0 0.69 10.8 0.0 2.5 3 0 0 3 3 3 0 Cdc42 effector Inhibitor_I9 PF05922.11 EGG01428.1 - 3.4e-05 24.3 0.2 0.0001 22.7 0.2 1.9 1 1 0 1 1 1 1 Peptidase inhibitor I9 B PF02216.11 EGG01428.1 - 0.11 12.3 3.5 6.9 6.5 0.1 3.5 4 0 0 4 4 4 0 B domain Macoilin PF09726.4 EGG01428.1 - 0.13 10.4 3.0 0.16 10.2 2.0 1.1 1 0 0 1 1 1 0 Transmembrane protein ERM PF00769.14 EGG01428.1 - 8.8 5.7 8.5 0.67 9.4 2.7 1.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Macoilin PF09726.4 EGG01429.1 - 0.052 11.8 1.3 0.061 11.6 0.9 1.0 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 EGG01429.1 - 5.6 6.3 7.0 8.3 5.8 4.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_hydro_10 PF00331.15 EGG01430.1 - 2.7e-90 302.6 0.0 3.2e-90 302.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 L51_S25_CI-B8 PF05047.11 EGG01431.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Dicty_REP PF05086.7 EGG01432.1 - 0.8 7.3 4.7 1 7.0 3.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Jnk-SapK_ap_N PF09744.4 EGG01433.1 - 0.081 12.9 10.3 0.22 11.4 0.4 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1515 PF07439.6 EGG01433.1 - 0.26 11.0 3.4 3.7 7.3 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Flagellin_C PF00700.16 EGG01433.1 - 0.27 11.4 6.0 5.4 7.2 0.4 3.3 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region Laminin_II PF06009.7 EGG01433.1 - 3.5 7.3 14.4 1.4 8.7 3.0 2.5 1 1 1 2 2 2 0 Laminin Domain II Exo_endo_phos PF03372.18 EGG01434.1 - 2e-22 80.3 0.0 3.2e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EGG01434.1 - 0.00019 21.1 3.2 0.00025 20.8 0.9 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat RNA_lig_T4_1 PF09511.5 EGG01435.1 - 2.9e-60 203.5 0.0 5.2e-60 202.6 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 EGG01435.1 - 1.6e-20 73.6 0.0 4.8e-14 52.5 0.0 2.9 2 1 1 3 3 3 2 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 EGG01435.1 - 6.4e-19 68.1 0.1 2.2e-18 66.4 0.0 2.0 2 1 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain SKI PF01202.17 EGG01435.1 - 0.08 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase DPBB_1 PF03330.13 EGG01436.1 - 5.6e-10 39.0 0.0 9e-10 38.4 0.0 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGG01436.1 - 0.0025 17.4 0.0 0.0044 16.6 0.0 1.3 1 1 0 1 1 1 1 Barwin family UPF1_Zn_bind PF09416.5 EGG01437.1 - 7.7e-68 226.8 1.3 1.5e-67 225.9 0.4 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.1 EGG01437.1 - 2.2e-20 73.2 0.6 3.6e-20 72.5 0.4 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGG01437.1 - 3.6e-15 55.4 0.2 4.8e-14 51.8 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EGG01437.1 - 2.9e-10 40.0 0.0 5.2e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EGG01437.1 - 7.9e-07 29.0 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EGG01437.1 - 0.00065 19.0 0.0 0.00095 18.5 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EGG01437.1 - 0.00071 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.4 EGG01437.1 - 0.00098 18.1 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.17 EGG01437.1 - 0.0094 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain DEAD PF00270.24 EGG01437.1 - 0.013 15.0 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.1 EGG01437.1 - 0.033 14.1 0.1 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 EGG01437.1 - 0.039 12.8 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EGG01437.1 - 0.04 14.0 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGG01437.1 - 0.051 12.8 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 EGG01437.1 - 0.052 12.9 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGG01437.1 - 0.067 12.6 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 EGG01437.1 - 0.086 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGG01437.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ParA PF10609.4 EGG01437.1 - 0.12 12.3 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 ParA/MinD ATPase like Ribosomal_S27e PF01667.12 EGG01437.1 - 0.33 10.5 7.0 0.032 13.7 1.6 1.7 2 0 0 2 2 1 0 Ribosomal protein S27 Cation_efflux PF01545.16 EGG01439.1 - 2.5e-64 217.1 1.2 3.1e-64 216.7 0.8 1.1 1 0 0 1 1 1 1 Cation efflux family U79_P34 PF03064.11 EGG01439.1 - 0.0062 16.0 1.4 0.0089 15.5 0.9 1.1 1 0 0 1 1 1 1 HSV U79 / HCMV P34 Zip PF02535.17 EGG01439.1 - 2.2 7.1 44.7 4.1 6.3 0.4 2.7 1 1 0 2 2 2 0 ZIP Zinc transporter Prenyltrans PF00432.16 EGG01441.1 - 3.7e-57 189.5 3.4 1.8e-12 46.5 0.1 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGG01441.1 - 1.6e-34 118.6 0.3 7e-15 55.4 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGG01441.1 - 8.3e-07 29.0 0.1 0.001 19.0 0.1 3.1 1 1 2 3 3 3 2 Prenyltransferase-like BRCT PF00533.21 EGG01442.1 - 8.6e-10 38.6 0.1 2.3e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGG01442.1 - 2.1e-05 24.2 0.5 5.2e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 twin BRCT domain Dsh_C PF12316.3 EGG01442.1 - 0.47 10.5 7.4 0.71 9.9 5.0 1.5 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DSPc PF00782.15 EGG01443.1 - 2.3e-05 24.0 0.2 6.5e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 EGG01443.1 - 8.7e-05 22.0 0.1 0.00016 21.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EGG01443.1 - 0.0074 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 EGG01443.1 - 0.17 11.2 0.9 0.79 9.0 0.6 2.0 1 1 0 1 1 1 0 Protein-tyrosine phosphatase bZIP_1 PF00170.16 EGG01444.1 - 0.00021 21.1 8.3 0.00021 21.1 5.8 2.5 2 1 0 2 2 2 1 bZIP transcription factor HAUS6_N PF14661.1 EGG01444.1 - 0.0079 15.5 5.9 0.015 14.7 4.1 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Alpha_kinase PF02816.13 EGG01446.1 - 1.4e-13 50.9 0.0 6.7e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Alpha-kinase family TetM_leader PF08076.6 EGG01446.1 - 0.12 11.9 0.6 0.43 10.1 0.1 2.1 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide Arginosuc_synth PF00764.14 EGG01447.1 - 5.5e-143 476.6 0.0 6.6e-143 476.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EGG01447.1 - 0.00053 19.3 0.0 0.00088 18.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EGG01447.1 - 0.00056 19.4 0.0 0.0009 18.8 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 EGG01447.1 - 0.013 14.0 0.0 0.02 13.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase bZIP_1 PF00170.16 EGG01448.1 - 3.3e-11 42.9 10.9 7.4e-11 41.8 7.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF972 PF06156.8 EGG01448.1 - 0.069 13.5 0.5 0.069 13.5 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EGG01448.1 - 0.18 11.6 17.8 0.13 12.0 9.1 2.3 1 1 1 2 2 2 0 Basic region leucine zipper TSC22 PF01166.13 EGG01448.1 - 0.32 10.9 3.1 0.78 9.7 2.2 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.10 EGG01448.1 - 0.93 9.0 4.3 1.8 8.0 3.0 1.5 1 0 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.14 EGG01448.1 - 1.6 6.4 3.5 2.2 6.0 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glucosamine_iso PF01182.15 EGG01450.1 - 1.9e-62 210.5 0.0 2.4e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ras PF00071.17 EGG01451.1 - 4.5e-52 175.6 0.1 1.2e-51 174.3 0.1 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGG01451.1 - 1e-17 64.7 0.0 1.5e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG01451.1 - 1.8e-10 40.3 0.0 3.9e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGG01451.1 - 6.7e-08 32.1 0.0 9.6e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGG01451.1 - 3.2e-06 27.0 0.0 4.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGG01451.1 - 4.3e-06 26.0 0.0 7.4e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EGG01451.1 - 0.00046 20.3 0.0 0.00074 19.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 EGG01451.1 - 0.00095 18.2 0.1 0.02 13.9 0.0 2.1 2 0 0 2 2 2 1 Septin DUF258 PF03193.11 EGG01451.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EGG01451.1 - 0.004 16.8 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase PduV-EutP PF10662.4 EGG01451.1 - 0.0046 16.4 0.1 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EGG01451.1 - 0.0059 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EGG01451.1 - 0.0094 15.5 0.1 0.63 9.5 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EGG01451.1 - 0.0095 15.4 0.1 0.018 14.5 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EGG01451.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EGG01451.1 - 0.019 15.2 0.0 0.031 14.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter MobB PF03205.9 EGG01451.1 - 0.025 14.2 0.1 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EGG01451.1 - 0.065 12.8 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.5 EGG01451.1 - 0.072 12.3 0.0 0.16 11.1 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 EGG01451.1 - 0.095 12.4 0.0 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NIF PF03031.13 EGG01452.1 - 4e-48 163.0 0.1 4.5e-48 162.9 0.1 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EGG01452.1 - 0.0052 17.0 0.1 0.095 12.9 0.0 2.0 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 EGG01453.1 - 1.9e-12 46.5 0.4 7e-05 22.5 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Ribonucleas_3_2 PF11469.3 EGG01455.1 - 0.013 15.7 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease III Glyco_hydro_10 PF00331.15 EGG01456.1 - 5.3e-94 314.8 0.0 6.5e-94 314.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF2120 PF09893.4 EGG01456.1 - 0.026 14.4 0.0 0.069 13.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Pkinase PF00069.20 EGG01457.1 - 6.7e-43 146.7 0.0 4e-42 144.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG01457.1 - 1.2e-22 80.2 0.1 1.4e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGG01457.1 - 2.7e-05 23.2 0.1 0.013 14.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGG01457.1 - 0.0094 15.6 0.1 0.17 11.5 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGG01457.1 - 0.048 13.0 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EGG01457.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 EGG01458.1 - 2.7e-10 39.5 33.5 2.7e-09 36.2 11.2 3.0 2 2 1 3 3 3 2 Major Facilitator Superfamily DUF1145 PF06611.7 EGG01458.1 - 0.19 11.4 3.6 3.7 7.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1145) Pterin_4a PF01329.14 EGG01459.1 - 7e-15 54.5 0.0 9.3e-15 54.1 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase PPP1R35_C PF15503.1 EGG01461.1 - 0.079 12.4 0.1 0.079 12.4 0.1 2.3 3 0 0 3 3 3 0 Protein phosphatase 1 regulatory subunit 35 C-terminus SRF-TF PF00319.13 EGG01469.1 - 4.8e-17 60.9 0.0 4.8e-17 60.9 0.0 1.8 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) IncA PF04156.9 EGG01470.1 - 0.0048 16.5 3.7 0.0057 16.2 1.2 1.9 2 0 0 2 2 2 1 IncA protein Mur_ligase_M PF08245.7 EGG01471.1 - 1.4e-05 25.2 0.0 5.1e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Pho88 PF10032.4 EGG01472.1 - 4.2e-68 228.3 0.5 4.6e-68 228.2 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) CitMHS PF03600.11 EGG01472.1 - 0.095 11.2 0.3 0.12 10.9 0.2 1.2 1 0 0 1 1 1 0 Citrate transporter Ribonuclease_T2 PF00445.13 EGG01473.1 - 2.3e-36 125.2 1.9 4.2e-36 124.3 1.3 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Glyco_hydro_7 PF00840.15 EGG01475.1 - 3.3e-191 635.3 13.3 3.8e-191 635.1 9.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 PAP2 PF01569.16 EGG01481.1 - 5.1e-28 97.3 1.8 5.1e-28 97.3 1.3 1.5 2 0 0 2 2 2 1 PAP2 superfamily EPL1 PF10513.4 EGG01483.1 - 2.6e-25 89.5 0.1 2.6e-25 89.5 0.1 2.1 2 0 0 2 2 2 1 Enhancer of polycomb-like PRA1 PF03208.14 EGG01485.1 - 0.18 11.1 0.9 0.26 10.5 0.6 1.2 1 0 0 1 1 1 0 PRA1 family protein ING PF12998.2 EGG01486.1 - 6.7e-10 39.1 0.0 1.7e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EGG01486.1 - 3.6e-09 36.1 7.7 6.8e-09 35.2 5.3 1.5 1 0 0 1 1 1 1 PHD-finger L27 PF02828.11 EGG01486.1 - 0.046 13.4 0.5 0.12 12.1 0.3 1.7 1 0 0 1 1 1 0 L27 domain F-box-like PF12937.2 EGG01487.1 - 0.0027 17.3 0.1 0.023 14.4 0.0 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EGG01487.1 - 0.0053 16.3 0.1 3 7.5 0.0 2.9 2 0 0 2 2 2 2 F-box domain Complex1_LYR PF05347.10 EGG01488.1 - 5e-08 32.6 0.8 5e-08 32.6 0.5 2.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGG01488.1 - 7.4e-06 26.0 0.5 7.4e-06 26.0 0.4 2.9 3 0 0 3 3 3 1 Complex1_LYR-like DUF4606 PF15379.1 EGG01488.1 - 0.25 11.4 4.8 0.34 10.9 0.2 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4606) CDC73 PF05179.9 EGG01489.1 - 1.1e-37 129.8 2.3 1.1e-37 129.8 1.6 2.0 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family Pkinase PF00069.20 EGG01491.1 - 2e-05 23.8 0.0 2.4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain GBP PF02263.14 EGG01491.1 - 0.058 12.4 0.1 0.087 11.8 0.0 1.3 1 1 0 1 1 1 0 Guanylate-binding protein, N-terminal domain GldH_lipo PF14109.1 EGG01491.1 - 0.07 13.3 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 GldH lipoprotein Nicastrin PF05450.10 EGG01492.1 - 0.036 13.3 1.0 0.047 12.9 0.7 1.3 1 0 0 1 1 1 0 Nicastrin Kelch_4 PF13418.1 EGG01494.1 - 7.7e-12 44.7 2.4 0.00025 20.7 0.1 4.2 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EGG01494.1 - 7.4e-10 38.1 0.3 0.001 18.7 0.0 4.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 EGG01494.1 - 2.3e-09 37.0 1.3 0.014 15.5 0.1 4.5 3 1 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 EGG01494.1 - 1.8e-08 34.1 3.9 0.00037 20.3 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EGG01494.1 - 7.3e-08 31.8 0.0 0.0067 15.9 0.0 3.2 3 1 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 EGG01494.1 - 1.1e-07 31.8 14.7 0.0017 18.4 0.0 6.1 5 1 0 5 5 5 2 Galactose oxidase, central domain BTB PF00651.26 EGG01494.1 - 0.026 14.4 0.1 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain Nuc_sug_transp PF04142.10 EGG01495.1 - 7.3e-71 238.1 6.2 1.2e-70 237.4 4.3 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EGG01495.1 - 1.8e-10 40.9 15.2 4.5e-09 36.5 1.2 2.4 2 0 0 2 2 2 2 Multidrug resistance efflux transporter UAA PF08449.6 EGG01495.1 - 7.6e-08 31.6 13.9 1e-07 31.2 9.6 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGG01495.1 - 7.3e-05 22.8 3.2 7.3e-05 22.8 2.2 3.0 4 0 0 4 4 4 2 EamA-like transporter family DUF2427 PF10348.4 EGG01495.1 - 0.0097 15.4 0.1 0.0097 15.4 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF202 PF02656.10 EGG01495.1 - 0.3 11.3 0.1 0.3 11.3 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF202) TPT PF03151.11 EGG01495.1 - 1.1 8.8 21.8 0.015 14.9 5.6 3.0 2 1 0 2 2 2 0 Triose-phosphate Transporter family MgtC PF02308.11 EGG01495.1 - 5.7 6.7 9.3 0.37 10.6 0.7 2.9 3 1 1 4 4 4 0 MgtC family AlaDh_PNT_N PF05222.10 EGG01496.1 - 9.5e-27 93.6 0.0 1.3e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EGG01496.1 - 4.3e-14 52.4 0.0 6.6e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TPK_catalytic PF04263.11 EGG01497.1 - 2.8e-26 91.5 0.0 4.8e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EGG01497.1 - 4.8e-16 58.2 0.3 8.1e-16 57.4 0.2 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Methyltransf_33 PF10017.4 EGG01497.1 - 0.099 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent AA_permease_2 PF13520.1 EGG01499.1 - 0.26 9.7 0.0 0.36 9.3 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease UDG PF03167.14 EGG01501.1 - 1.3e-22 79.8 0.0 2.5e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily Clr5 PF14420.1 EGG01502.1 - 0.00017 21.4 0.0 0.66 9.9 0.0 2.8 3 0 0 3 3 3 2 Clr5 domain HTH_21 PF13276.1 EGG01502.1 - 0.007 16.3 0.1 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 HTH-like domain DUF604 PF04646.7 EGG01503.1 - 3.8e-12 45.9 0.0 7.6e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EGG01503.1 - 3e-07 29.9 0.0 5.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Fringe-like NAD_binding_8 PF13450.1 EGG01506.1 - 1.1e-12 47.7 0.0 2.3e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGG01506.1 - 0.00023 20.1 0.1 0.00032 19.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGG01506.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGG01506.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EGG01506.1 - 0.0073 15.4 0.0 0.0086 15.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EGG01506.1 - 0.036 13.9 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGG01506.1 - 0.074 11.4 0.1 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EGG01506.1 - 0.11 12.8 0.2 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_47 PF01532.15 EGG01508.1 - 2e-148 494.7 0.0 2.6e-148 494.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DEC-1_N PF04625.8 EGG01509.1 - 0.23 10.0 3.4 0.28 9.7 2.4 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Retinal PF15449.1 EGG01509.1 - 0.53 7.8 8.5 0.59 7.7 5.9 1.1 1 0 0 1 1 1 0 Retinal protein TFIIA PF03153.8 EGG01512.1 - 8.3 6.1 14.5 9.2 6.0 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAZ_siRNAbind PF12212.3 EGG01513.1 - 0.023 14.2 0.5 0.06 12.9 0.0 1.9 2 0 0 2 2 2 0 Piwi/Argonaute/Zwille siRNA-binding domain DUF1510 PF07423.6 EGG01513.1 - 0.9 8.8 14.1 1.3 8.3 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 EGG01513.1 - 2.9 6.8 18.7 4.8 6.1 12.9 1.3 1 0 0 1 1 1 0 BUD22 Zn_ribbon_recom PF13408.1 EGG01514.1 - 1.2 9.4 6.3 1.7 8.9 3.1 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Gly_transf_sug PF04488.10 EGG01515.1 - 9.7e-07 29.1 0.5 8.7e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EGG01515.1 - 0.00012 20.6 0.1 0.0004 19.0 0.0 1.8 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Macoilin PF09726.4 EGG01515.1 - 0.018 13.3 2.3 0.019 13.2 1.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Atg8 PF02991.11 EGG01516.1 - 2.3e-52 175.3 0.1 2.7e-52 175.0 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EGG01516.1 - 7.9e-07 29.1 0.0 9.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Aspzincin_M35 PF14521.1 EGG01519.1 - 0.062 13.8 0.0 0.092 13.2 0.0 1.3 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase DUF2704 PF10866.3 EGG01521.1 - 0.0038 16.6 0.4 0.0073 15.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2704) Thiolase_N PF00108.18 EGG01522.1 - 1.5e-81 273.2 4.7 1.5e-81 273.2 3.2 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGG01522.1 - 4e-40 136.0 0.1 4e-40 136.0 0.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGG01522.1 - 0.003 17.0 0.8 0.003 17.0 0.5 2.7 4 0 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain FAR1 PF03101.10 EGG01525.1 - 7e-05 23.2 2.4 8.4e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.6 EGG01525.1 - 0.00092 19.3 0.1 0.00092 19.3 0.1 2.8 3 0 0 3 3 3 1 Transcription factor AFT PH_3 PF14593.1 EGG01529.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 PH domain OTU PF02338.14 EGG01530.1 - 7.5e-14 52.3 0.1 1.3e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGG01530.1 - 0.0041 16.5 0.0 0.11 11.8 0.1 2.3 1 1 1 2 2 2 1 Peptidase C65 Otubain Ery_res_leader1 PF08051.6 EGG01530.1 - 0.02 14.5 0.1 0.02 14.5 0.1 2.1 2 0 0 2 2 2 0 Erythromycin resistance leader peptide OTU PF02338.14 EGG01531.1 - 2.3e-20 73.3 0.0 3.6e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGG01531.1 - 8.9e-05 21.9 0.1 0.2 11.0 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain PIG-P PF08510.7 EGG01532.1 - 3.2e-21 75.2 1.0 4.1e-21 74.9 0.7 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.7 EGG01532.1 - 0.0096 16.1 4.7 0.017 15.3 3.3 1.4 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) OTU PF02338.14 EGG01533.1 - 1.9e-24 86.5 0.0 5.9e-15 55.9 0.0 2.3 2 0 0 2 2 2 2 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGG01533.1 - 2.8e-09 36.7 0.1 0.00051 19.4 0.0 3.2 2 1 1 3 3 3 3 Peptidase C65 Otubain OTU PF02338.14 EGG01534.1 - 8.6e-16 58.6 0.7 1.8e-15 57.6 0.5 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGG01534.1 - 2.2e-05 23.9 1.2 0.0018 17.7 0.6 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain OTU PF02338.14 EGG01535.1 - 6.3e-15 55.8 0.1 1.1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGG01535.1 - 3.9e-06 26.3 3.3 5.2e-05 22.7 0.2 2.1 1 1 1 2 2 2 2 Peptidase C65 Otubain Mem_trans PF03547.13 EGG01537.1 - 1e-41 142.5 0.0 7.9e-41 139.6 0.0 2.3 1 1 0 1 1 1 1 Membrane transport protein His_Phos_2 PF00328.17 EGG01538.1 - 2.5e-38 132.3 0.0 3.2e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AATF-Che1 PF13339.1 EGG01539.1 - 0.084 13.0 3.5 0.048 13.8 1.0 1.6 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor RXT2_N PF08595.6 EGG01540.1 - 0.25 11.1 3.7 0.32 10.7 2.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Septin PF00735.13 EGG01545.1 - 3.1e-23 82.1 1.1 3.1e-23 82.1 0.8 2.4 2 1 0 2 2 2 1 Septin DUF2833 PF11090.3 EGG01545.1 - 0.053 13.7 0.4 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) Strep_SA_rep PF06696.6 EGG01545.1 - 0.3 10.8 0.1 0.3 10.8 0.0 2.2 2 0 0 2 2 2 0 Streptococcal surface antigen repeat UPF0449 PF15136.1 EGG01545.1 - 2.4 8.4 5.4 1.3 9.3 2.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 IncA PF04156.9 EGG01545.1 - 3.6 7.1 10.4 5.5 6.5 7.2 1.4 1 1 0 1 1 1 0 IncA protein DUF2724 PF10893.3 EGG01549.1 - 0.023 14.5 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) GCM PF03615.10 EGG01552.1 - 0.032 13.8 1.3 0.1 12.1 0.9 1.8 1 1 0 1 1 1 0 GCM motif protein Pollen_Ole_e_I PF01190.12 EGG01553.1 - 0.023 14.5 0.7 0.031 14.1 0.5 1.2 1 0 0 1 1 1 0 Pollen proteins Ole e I like LIM PF00412.17 EGG01555.1 - 6.7e-29 99.7 31.4 1.8e-12 47.1 4.0 5.0 4 1 0 4 4 4 4 LIM domain COX4 PF02936.9 EGG01559.1 - 1.9e-34 118.4 0.0 2.4e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1289 PF06945.8 EGG01559.1 - 1.2 8.6 0.0 1.2 8.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1289) NMT1 PF09084.6 EGG01561.1 - 3.5e-70 235.9 0.0 4.6e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EGG01561.1 - 0.00035 20.0 0.2 2.2 7.6 0.1 3.0 2 1 0 3 3 3 2 NMT1-like family WD40 PF00400.27 EGG01562.1 - 1.9e-06 27.5 0.0 2.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat Nup160 PF11715.3 EGG01562.1 - 0.065 11.3 0.0 0.065 11.3 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 EF-hand_4 PF12763.2 EGG01563.1 - 9.9e-42 140.9 0.0 2e-17 62.8 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 EGG01563.1 - 1.5e-08 34.2 0.0 3.8e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 EGG01563.1 - 1.2e-06 28.5 0.0 0.0091 16.1 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair IncA PF04156.9 EGG01563.1 - 4e-05 23.3 3.5 4e-05 23.3 2.4 2.2 1 1 1 2 2 2 1 IncA protein EF-hand_1 PF00036.27 EGG01563.1 - 5.2e-05 22.2 0.0 0.21 10.9 0.0 3.9 4 0 0 4 4 4 1 EF hand WEMBL PF05701.6 EGG01563.1 - 0.0005 18.6 11.2 0.00073 18.1 7.8 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light CALCOCO1 PF07888.6 EGG01563.1 - 0.0012 17.3 9.3 0.0018 16.6 6.4 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like EF-hand_6 PF13405.1 EGG01563.1 - 0.0037 17.0 0.1 36 4.6 0.0 4.1 3 0 0 3 3 3 0 EF-hand domain CENP-Q PF13094.1 EGG01563.1 - 0.0061 16.6 13.5 0.018 15.0 9.4 1.8 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF2730 PF10805.3 EGG01563.1 - 0.011 15.4 10.2 0.18 11.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) AAA_13 PF13166.1 EGG01563.1 - 0.015 13.7 8.1 0.024 13.1 5.6 1.2 1 0 0 1 1 1 0 AAA domain FUSC PF04632.7 EGG01563.1 - 0.024 13.1 4.3 0.045 12.1 3.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Vps51 PF08700.6 EGG01563.1 - 0.03 14.1 11.2 0.45 10.4 0.9 2.9 1 1 1 2 2 2 0 Vps51/Vps67 KSR1-SAM PF13543.1 EGG01563.1 - 0.069 12.9 7.8 0.13 12.0 5.4 1.4 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 UBA_3 PF09288.5 EGG01563.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain TBPIP PF07106.8 EGG01563.1 - 0.076 12.5 15.6 0.48 9.9 9.2 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF745 PF05335.8 EGG01563.1 - 0.14 11.6 9.6 0.84 9.1 7.4 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF745) ATG16 PF08614.6 EGG01563.1 - 0.16 11.8 18.5 0.18 11.5 0.6 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.14 EGG01563.1 - 0.21 9.3 5.8 0.31 8.8 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 EGG01563.1 - 0.27 11.4 5.0 7.9 6.8 0.4 3.2 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 EGG01563.1 - 0.43 9.5 12.9 0.75 8.7 9.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 TMCO5 PF14992.1 EGG01563.1 - 0.61 9.1 13.0 0.98 8.4 9.0 1.2 1 0 0 1 1 1 0 TMCO5 family DUF1664 PF07889.7 EGG01563.1 - 0.71 9.6 9.7 20 4.9 2.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 EGG01563.1 - 0.73 8.9 10.5 2.2 7.3 2.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein MscS_porin PF12795.2 EGG01563.1 - 0.93 8.7 23.3 6.9 5.9 10.1 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Val_tRNA-synt_C PF10458.4 EGG01563.1 - 1.2 9.2 9.5 0.84 9.7 0.1 3.0 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm ADIP PF11559.3 EGG01563.1 - 1.5 8.7 22.8 0.8 9.5 5.6 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.7 EGG01563.1 - 2.2 8.7 15.2 6.5 7.2 0.1 4.0 1 1 2 3 3 3 0 SlyX TMF_TATA_bd PF12325.3 EGG01563.1 - 7.4 6.3 22.4 39 3.9 2.5 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding ATG_C PF09333.6 EGG01564.1 - 4.5e-24 84.4 0.1 1.6e-23 82.6 0.0 2.1 2 0 0 2 2 2 1 ATG C terminal domain ATG2_CAD PF13329.1 EGG01564.1 - 0.00049 19.7 0.1 0.0092 15.5 0.0 3.2 3 0 0 3 3 3 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.2 EGG01564.1 - 0.064 12.7 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 N-terminal region of Chorein, a TM vesicle-mediated sorter Prefoldin PF02996.12 EGG01564.1 - 0.48 10.0 3.4 1.7 8.3 0.8 2.4 2 0 0 2 2 2 0 Prefoldin subunit SUZ PF12752.2 EGG01565.1 - 2.6e-09 37.4 2.4 2.6e-09 37.4 1.7 5.1 5 0 0 5 5 5 1 SUZ domain R3H PF01424.17 EGG01565.1 - 0.0024 17.5 0.0 0.0074 15.9 0.0 1.8 1 0 0 1 1 1 1 R3H domain DUF3722 PF12519.3 EGG01566.1 - 6.7e-67 225.4 0.8 1e-66 224.8 0.4 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EGG01566.1 - 0.0057 16.0 0.0 0.025 13.9 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic porin Pkinase PF00069.20 EGG01567.1 - 1.3e-73 247.3 0.0 1.4e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG01567.1 - 7.7e-32 110.3 0.0 9.8e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG01567.1 - 0.00023 20.2 0.0 0.0016 17.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGG01567.1 - 0.0066 16.1 0.0 0.014 15.1 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGG01567.1 - 0.014 14.2 0.1 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FA_hydroxylase PF04116.8 EGG01568.1 - 5.4e-12 46.1 21.2 5.4e-12 46.1 14.7 2.6 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily DSPc PF00782.15 EGG01571.1 - 4.3e-27 94.3 0.0 6.9e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGG01571.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGG01571.1 - 0.027 14.5 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Proteasom_Rpn13 PF04683.8 EGG01572.1 - 4.8e-15 55.4 0.0 7.4e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor CUB_2 PF02408.15 EGG01580.1 - 0.0047 16.4 0.6 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 CUB-like domain Chs3p PF12271.3 EGG01583.1 - 2.6e-22 79.1 4.9 3.1e-22 78.9 3.4 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Caps_synth_CapC PF14102.1 EGG01583.1 - 0.037 14.1 5.7 0.032 14.3 2.9 1.6 1 1 0 1 1 1 0 Capsule biosynthesis CapC DUF2569 PF10754.4 EGG01583.1 - 0.28 11.4 5.1 0.41 10.8 3.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) ABC_membrane_2 PF06472.10 EGG01584.1 - 3.7e-95 318.2 4.0 5.6e-95 317.6 2.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGG01584.1 - 2.4e-18 66.7 0.0 5.1e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGG01584.1 - 0.00019 21.4 1.1 0.00057 19.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EGG01584.1 - 0.0027 18.0 3.6 0.034 14.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EGG01584.1 - 0.019 14.4 0.0 0.061 12.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 EGG01584.1 - 0.027 13.7 0.0 0.098 11.8 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGG01584.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EGG01584.1 - 0.075 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 WD40 PF00400.27 EGG01585.1 - 9.3e-27 91.9 10.4 3.9e-09 36.0 0.4 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 EGG01585.1 - 0.014 14.4 0.7 0.17 10.8 0.1 2.6 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3639 PF12341.3 EGG01585.1 - 0.026 14.5 0.3 0.026 14.5 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3639) PDGLE PF13190.1 EGG01585.1 - 0.074 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 PDGLE domain DUF4354 PF14263.1 EGG01586.1 - 0.04 13.6 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) Poxvirus PF06227.7 EGG01586.1 - 0.047 13.2 0.4 0.071 12.6 0.3 1.2 1 0 0 1 1 1 0 dsDNA Poxvirus Ammonium_transp PF00909.16 EGG01588.1 - 2.1e-96 322.8 30.5 2.5e-96 322.6 21.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family ORC3_N PF07034.6 EGG01590.1 - 2.5e-30 105.5 0.6 5e-30 104.5 0.4 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Ammonium_transp PF00909.16 EGG01591.1 - 3.6e-101 338.5 26.7 4.1e-101 338.3 18.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family GP38 PF05268.6 EGG01594.1 - 0.0028 17.1 0.8 0.0041 16.5 0.6 1.2 1 0 0 1 1 1 1 Phage tail fibre adhesin Gp38 Pinin_SDK_N PF04697.8 EGG01594.1 - 0.12 12.3 2.9 0.21 11.5 2.0 1.5 1 0 0 1 1 1 0 pinin/SDK conserved region RR_TM4-6 PF06459.7 EGG01596.1 - 1.4 8.7 11.1 1.8 8.3 7.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.7 EGG01596.1 - 5 4.9 21.9 5.3 4.8 15.2 1.0 1 0 0 1 1 1 0 Nop14-like family FadA PF09403.5 EGG01598.1 - 0.017 15.1 3.4 0.017 15.1 2.4 2.4 2 0 0 2 2 2 0 Adhesion protein FadA RNB PF00773.14 EGG01598.1 - 0.47 9.6 3.7 0.59 9.3 2.6 1.2 1 0 0 1 1 1 0 RNB domain Radical_SAM PF04055.16 EGG01599.1 - 3.9e-16 59.6 0.0 8.5e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EGG01599.1 - 1.3e-10 41.1 0.0 3.7e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGG01599.1 - 0.084 13.0 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGG01599.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF1296 PF06972.6 EGG01601.1 - 0.066 13.1 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) DcpS_C PF11969.3 EGG01605.1 - 4.5e-25 88.1 0.1 9.1e-25 87.1 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Alpha_kinase PF02816.13 EGG01608.1 - 1.6e-10 40.9 0.2 3.2e-10 39.9 0.1 1.5 1 1 0 1 1 1 1 Alpha-kinase family zf-C3HC4 PF00097.20 EGG01609.1 - 0.029 14.0 3.1 0.09 12.4 2.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SF-assemblin PF06705.6 EGG01609.1 - 0.13 11.3 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin zf-RING_2 PF13639.1 EGG01609.1 - 0.17 11.7 5.9 0.26 11.1 4.1 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_2 PF13639.1 EGG01613.1 - 4.6e-06 26.3 7.1 6.8e-06 25.8 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 EGG01613.1 - 0.00039 19.9 8.7 0.00068 19.1 6.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EGG01613.1 - 0.00087 18.9 7.0 0.0014 18.2 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG01613.1 - 0.0034 17.0 7.4 0.0054 16.3 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG01613.1 - 0.012 15.6 7.8 0.019 14.9 5.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 EGG01613.1 - 0.049 13.3 4.6 0.096 12.4 3.2 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.1 EGG01613.1 - 0.91 9.2 7.5 1.8 8.3 5.2 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 EGG01613.1 - 1.1 9.1 4.7 3.4 7.5 3.3 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pyr_redox_2 PF07992.9 EGG01614.1 - 1.2e-19 70.9 1.8 2.4e-16 60.2 0.0 3.0 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGG01614.1 - 4.2e-14 52.7 0.6 1.4e-10 41.3 0.0 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EGG01614.1 - 1.9e-11 42.4 3.5 1.2e-06 27.3 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGG01614.1 - 8.8e-10 38.5 4.2 8.1e-08 32.2 0.7 2.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EGG01614.1 - 1.3e-09 37.1 1.0 0.00075 19.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EGG01614.1 - 2.5e-08 32.8 2.6 2.2e-05 23.5 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EGG01614.1 - 0.00013 21.4 5.3 0.00092 18.7 2.8 2.5 1 1 1 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.1 EGG01614.1 - 0.00032 20.8 0.2 0.57 10.2 0.0 3.3 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_4 PF12763.2 EGG01614.1 - 0.014 15.1 1.2 0.5 10.1 0.1 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGG01614.1 - 0.016 15.2 5.8 0.17 11.8 0.1 2.9 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF948 PF06103.6 EGG01614.1 - 0.14 12.0 0.4 0.39 10.6 0.3 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Parathyroid PF01279.12 EGG01614.1 - 0.15 12.6 1.9 4.9 7.8 0.0 2.5 2 0 0 2 2 2 0 Parathyroid hormone family 3-alpha PF03475.9 EGG01616.1 - 0.16 11.7 0.6 0.34 10.6 0.4 1.6 1 0 0 1 1 1 0 3-alpha domain Peptidase_C54 PF03416.14 EGG01617.1 - 3.2e-11 42.8 0.0 4.2e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 BCL9 PF11502.3 EGG01618.1 - 0.032 13.7 0.3 0.19 11.2 0.1 2.2 2 0 0 2 2 2 0 B-cell lymphoma 9 protein DUF2119 PF09892.4 EGG01622.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) EF-1_beta_acid PF10587.4 EGG01622.1 - 0.13 12.4 0.1 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region AhpC-TSA_2 PF13911.1 EGG01625.1 - 3.3e-16 59.2 0.0 4.6e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGG01625.1 - 5.8e-05 22.7 0.0 8.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGG01625.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_2 PF13098.1 EGG01625.1 - 0.14 12.3 0.2 24 5.1 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain AhpC-TSA_2 PF13911.1 EGG01626.1 - 2.8e-13 49.7 0.1 1.8e-12 47.1 0.1 2.0 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGG01626.1 - 1.8e-05 24.4 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGG01626.1 - 0.024 14.1 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Redoxin AhpC-TSA_2 PF13911.1 EGG01628.1 - 1.4e-16 60.4 0.0 2e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGG01628.1 - 2e-05 24.2 0.0 2.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGG01628.1 - 0.018 14.5 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Redoxin DUF2196 PF09962.4 EGG01628.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) RecR PF02132.10 EGG01629.1 - 0.0082 15.5 1.2 0.19 11.2 0.1 2.3 2 0 0 2 2 2 1 RecR protein zf-RING_3 PF14369.1 EGG01629.1 - 0.03 14.3 1.8 0.058 13.3 0.4 1.9 2 0 0 2 2 2 0 zinc-finger PhnA_Zn_Ribbon PF08274.7 EGG01629.1 - 0.039 13.7 0.1 0.15 11.8 0.0 2.0 2 1 1 3 3 3 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.2 EGG01629.1 - 0.28 11.0 6.2 0.98 9.2 4.3 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain FYVE_2 PF02318.11 EGG01629.1 - 0.69 9.8 5.0 2.1 8.2 3.5 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger Cas_CXXC_CXXC PF09706.5 EGG01629.1 - 3.5 7.8 7.2 2.7 8.2 0.6 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) C1_2 PF03107.11 EGG01629.1 - 4.3 7.5 9.4 6.7 6.9 2.3 2.3 2 0 0 2 2 2 0 C1 domain Glyco_hydro_47 PF01532.15 EGG01630.1 - 8e-05 21.4 0.0 0.00012 20.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2222 PF09984.4 EGG01630.1 - 0.045 13.1 1.1 0.19 11.1 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) Glyco_hydro_47 PF01532.15 EGG01631.1 - 8.1e-120 400.5 0.0 9.3e-120 400.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rep_Org_C PF06926.6 EGG01636.1 - 0.022 14.8 0.8 0.048 13.7 0.2 1.8 1 1 0 1 1 1 0 Putative replisome organiser protein C-terminus DUF837 PF05769.6 EGG01636.1 - 0.033 13.7 1.2 0.057 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF837) GAS PF13851.1 EGG01638.1 - 0.0004 19.6 2.7 0.00068 18.8 1.8 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DASH_Dam1 PF08653.5 EGG01638.1 - 0.0064 16.2 1.6 1.2 8.9 0.1 2.4 2 0 0 2 2 2 2 DASH complex subunit Dam1 AKNA PF12443.3 EGG01638.1 - 0.0071 16.3 1.5 1.4 8.9 0.2 2.6 2 0 0 2 2 2 1 AT-hook-containing transcription factor Baculo_PEP_C PF04513.7 EGG01638.1 - 0.014 15.2 0.3 0.027 14.3 0.2 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EGG01638.1 - 0.022 13.9 0.7 0.035 13.2 0.5 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EGG01638.1 - 0.034 14.3 2.9 0.17 12.1 0.2 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MT PF12777.2 EGG01638.1 - 0.051 12.3 0.4 0.077 11.7 0.3 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Shugoshin_N PF07558.6 EGG01638.1 - 0.072 12.8 0.1 7.1 6.4 0.0 2.9 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region FlaC_arch PF05377.6 EGG01638.1 - 0.14 12.1 5.8 0.74 9.7 0.2 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1978 PF09321.5 EGG01638.1 - 0.27 10.6 4.9 0.43 9.9 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) DUF1664 PF07889.7 EGG01638.1 - 0.36 10.6 3.0 1.1 9.0 1.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Rop-like PF05082.8 EGG01638.1 - 2.4 7.7 4.7 8.9 5.8 0.1 2.4 2 0 0 2 2 2 0 Rop-like Mnd1 PF03962.10 EGG01638.1 - 2.8 7.5 7.2 27 4.3 4.9 2.1 1 1 0 1 1 1 0 Mnd1 family SlyX PF04102.7 EGG01638.1 - 4.3 7.7 6.4 41 4.6 0.1 2.9 1 1 1 2 2 2 0 SlyX ASF1_hist_chap PF04729.8 EGG01640.1 - 2.8e-62 208.9 0.9 2.8e-60 202.4 0.6 2.1 1 1 0 1 1 1 1 ASF1 like histone chaperone Dor1 PF04124.7 EGG01644.1 - 1.3e-12 46.8 3.1 1.5e-05 23.6 0.0 3.8 3 2 0 3 3 3 2 Dor1-like family Metallophos PF00149.23 EGG01645.1 - 5.7e-40 136.8 0.1 7e-40 136.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ALIX_LYPXL_bnd PF13949.1 EGG01649.1 - 0.0054 15.7 3.8 0.0084 15.1 2.7 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Herpes_UL25 PF01499.11 EGG01649.1 - 0.21 9.8 3.3 0.31 9.3 2.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family SR-25 PF10500.4 EGG01650.1 - 0.72 9.2 5.3 1.2 8.5 3.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Prolamin_like PF05617.6 EGG01652.1 - 0.055 13.6 0.1 0.079 13.1 0.1 1.3 1 0 0 1 1 1 0 Prolamin-like zf-CCHC PF00098.18 EGG01652.1 - 0.088 12.7 2.4 0.23 11.4 1.7 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGG01652.1 - 0.13 11.9 1.4 0.21 11.2 1.0 1.3 1 0 0 1 1 1 0 Zinc knuckle Ras PF00071.17 EGG01654.1 - 0.046 13.0 0.1 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Ras family KAR9 PF08580.5 EGG01654.1 - 0.26 9.5 5.5 0.33 9.1 3.8 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Lantibiotic_a PF14867.1 EGG01655.1 - 6.2 6.1 5.8 4.2 6.6 0.5 2.8 3 0 0 3 3 3 0 Lantibiotic alpha Pea-VEAacid PF08111.6 EGG01655.1 - 9.9 6.5 5.8 96 3.4 0.1 3.3 3 0 0 3 3 3 0 Pea-VEAacid family Trypan_PARP PF05887.6 EGG01657.1 - 5.8 6.7 7.7 7 6.4 5.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nuclease_act PF08133.6 EGG01659.1 - 0.11 11.9 1.2 0.22 11.0 0.9 1.4 1 0 0 1 1 1 0 Anticodon nuclease activator family Uricase PF01014.13 EGG01660.1 - 2.1e-54 183.3 0.0 4.8e-28 97.9 0.0 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L18ae PF01775.12 EGG01662.1 - 2e-59 198.9 0.7 2.4e-59 198.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain RINGv PF12906.2 EGG01664.1 - 4.6e-06 26.5 5.1 2.9e-05 23.9 3.5 2.1 1 1 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EGG01664.1 - 0.0091 15.8 2.5 0.0091 15.8 1.7 2.2 2 0 0 2 2 2 1 Ring finger domain AFT PF08731.6 EGG01665.1 - 0.00016 21.8 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 Transcription factor AFT FAR1 PF03101.10 EGG01665.1 - 0.0098 16.3 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain RRM_1 PF00076.17 EGG01666.1 - 3.5e-16 58.6 0.1 3.7e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG01666.1 - 7.9e-10 38.4 0.0 0.00082 19.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG01666.1 - 2.8e-05 24.0 0.0 0.0081 16.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EGG01669.1 - 3.7e-53 180.3 0.0 5.4e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG01669.1 - 1.2e-27 96.5 0.0 1.6e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG01669.1 - 0.003 16.5 0.0 0.0065 15.4 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EGG01669.1 - 0.0049 15.9 0.0 0.0085 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGG01669.1 - 0.026 14.1 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EGG01669.1 - 0.037 13.7 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EGG01669.1 - 0.074 12.3 0.0 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Acyltransferase PF01553.16 EGG01670.1 - 1.8e-13 50.0 0.1 4.1e-13 48.8 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase Pkinase PF00069.20 EGG01671.1 - 5.9e-45 153.4 0.0 8.4e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG01671.1 - 3e-40 137.9 0.0 4.6e-28 98.0 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EGG01671.1 - 0.048 12.7 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGG01671.1 - 0.12 12.0 0.1 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EGG01671.1 - 0.14 11.0 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DUF2663 PF10864.3 EGG01674.1 - 0.076 13.2 0.5 0.24 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Spore_YabQ PF09578.5 EGG01674.1 - 0.28 11.1 7.5 0.39 10.7 3.5 2.5 1 1 1 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) DUF3488 PF11992.3 EGG01676.1 - 0.0088 14.7 2.7 0.016 13.8 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3488) SHIPPO-rpt PF07004.7 EGG01678.1 - 0.14 13.0 0.3 5.5 8.0 0.0 2.4 2 1 0 2 2 2 0 Sperm-tail PG-rich repeat Pkinase PF00069.20 EGG01679.1 - 5.8e-42 143.6 0.0 8.5e-21 74.2 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGG01679.1 - 4.7e-19 68.4 0.0 1.6e-14 53.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase KA1 PF02149.14 EGG01679.1 - 6.3e-06 25.5 0.1 1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Golgin_A5 PF09787.4 EGG01680.1 - 0.019 13.4 0.4 0.024 13.1 0.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Vps53_N PF04100.7 EGG01680.1 - 0.046 12.5 0.6 0.066 11.9 0.4 1.3 1 1 0 1 1 1 0 Vps53-like, N-terminal Phage_GP20 PF06810.6 EGG01680.1 - 0.089 12.2 0.1 0.18 11.2 0.0 1.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 Syntaxin PF00804.20 EGG01680.1 - 0.4 10.8 2.2 3.4 7.8 0.1 2.1 2 0 0 2 2 2 0 Syntaxin Baculo_PEP_C PF04513.7 EGG01681.1 - 0.0007 19.4 0.2 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus SEO_N PF14576.1 EGG01681.1 - 0.0064 15.7 0.1 0.0089 15.3 0.1 1.2 1 0 0 1 1 1 1 Sieve element occlusion N-terminus CP12 PF02672.10 EGG01681.1 - 0.2 12.1 1.1 0.37 11.2 0.8 1.4 1 0 0 1 1 1 0 CP12 domain CaMKII_AD PF08332.5 EGG01682.1 - 0.089 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II Association DUF2191 PF09957.4 EGG01682.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2191) Myc_N PF01056.13 EGG01683.1 - 0.088 11.9 0.2 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region PCI PF01399.22 EGG01686.1 - 6.8e-09 35.9 0.0 1.9e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain Pkinase PF00069.20 EGG01687.1 - 3.6e-73 245.9 2.4 6e-73 245.1 0.2 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG01687.1 - 4.4e-52 176.7 0.3 4.4e-52 176.7 0.2 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EGG01687.1 - 1.8e-21 76.2 0.0 7.6e-21 74.2 0.0 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 EGG01687.1 - 2.5e-08 34.0 0.4 6e-08 32.8 0.3 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EGG01687.1 - 1.1e-06 27.8 0.0 2.6e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EGG01687.1 - 0.00013 22.2 0.2 0.019 15.1 0.0 2.6 1 1 1 2 2 2 1 Pleckstrin homology domain APH PF01636.18 EGG01687.1 - 0.0053 16.5 0.2 0.018 14.7 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF572 PF04502.8 EGG01690.1 - 4.3e-57 193.7 0.0 5.4e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Zn-ribbon_8 PF09723.5 EGG01690.1 - 0.048 13.6 0.3 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Esterase_phd PF10503.4 EGG01690.1 - 0.055 12.7 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Bromo_TP PF07524.8 EGG01691.1 - 3.6e-09 36.2 0.0 7.9e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated SRP9-21 PF05486.7 EGG01692.1 - 1.1e-17 63.5 0.4 1.1e-17 63.4 0.3 1.0 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Glyco_transf_25 PF01755.12 EGG01695.1 - 2.9e-07 30.3 1.4 0.0026 17.4 0.2 3.3 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) HTH_19 PF12844.2 EGG01695.1 - 0.052 13.6 0.9 0.15 12.0 0.6 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain CWC25 PF12542.3 EGG01697.1 - 3.3e-23 81.9 0.6 3.3e-23 81.9 0.4 3.8 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EGG01697.1 - 4.5e-12 45.7 11.9 4.5e-12 45.7 8.3 4.9 4 3 1 5 5 5 2 N-terminal domain of CBF1 interacting co-repressor CIR Kinase-PPPase PF03618.9 EGG01697.1 - 0.04 13.4 0.7 0.1 12.0 0.5 1.6 1 0 0 1 1 1 0 Kinase/pyrophosphorylase zf-H2C2_2 PF13465.1 EGG01698.1 - 2.1e-07 30.8 1.4 2.1e-07 30.8 1.0 2.4 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGG01698.1 - 5.6e-07 29.4 5.1 0.00048 20.2 0.1 2.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGG01698.1 - 2.3e-05 24.4 8.3 0.0078 16.4 0.3 2.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-BED PF02892.10 EGG01698.1 - 0.0088 15.7 2.7 1.8 8.3 0.1 2.7 2 1 1 3 3 3 2 BED zinc finger zf-C2H2_jaz PF12171.3 EGG01698.1 - 0.021 14.9 2.8 2.7 8.2 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGG01698.1 - 0.33 11.2 2.2 10 6.5 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Bap31 PF05529.7 EGG01700.1 - 9.6e-46 155.6 0.7 1.1e-45 155.5 0.5 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like CbiQ PF02361.11 EGG01700.1 - 0.1 12.1 2.6 0.15 11.6 1.8 1.3 1 0 0 1 1 1 0 Cobalt transport protein Pox_A_type_inc PF04508.7 EGG01700.1 - 0.55 10.1 3.9 0.22 11.4 0.6 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Tfb4 PF03850.9 EGG01701.1 - 6.2e-90 301.2 1.7 7.5e-90 300.9 1.2 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 UPF0258 PF06789.7 EGG01701.1 - 0.079 13.0 0.2 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) F-box-like_2 PF13013.1 EGG01702.1 - 0.71 9.6 5.5 0.17 11.5 0.7 2.1 2 2 0 2 2 2 0 F-box-like domain UPF0029 PF01205.14 EGG01705.1 - 2.1e-24 85.3 0.0 3.5e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 GA PF01468.12 EGG01705.1 - 0.045 13.9 0.2 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 GA module zf-B_box PF00643.19 EGG01707.1 - 0.15 11.9 7.8 0.31 10.9 0.8 2.2 2 0 0 2 2 2 0 B-box zinc finger WD40 PF00400.27 EGG01708.1 - 7.7e-34 114.3 15.0 6.8e-07 28.9 0.8 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat PADR1 PF08063.7 EGG01708.1 - 0.15 11.4 0.1 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2H2_4 PF13894.1 EGG01709.1 - 1e-06 28.6 6.3 0.011 15.9 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGG01709.1 - 3.2e-05 24.0 9.9 0.015 15.5 0.3 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG01709.1 - 0.00063 19.9 1.2 0.00063 19.9 0.8 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-BED PF02892.10 EGG01709.1 - 0.018 14.8 1.3 1.8 8.3 0.1 2.4 1 1 1 2 2 2 0 BED zinc finger LIM PF00412.17 EGG01709.1 - 0.083 12.9 0.3 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 LIM domain zf-C2HC_2 PF13913.1 EGG01709.1 - 0.33 10.6 5.2 0.32 10.6 1.7 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type LRR_4 PF12799.2 EGG01711.1 - 0.16 11.6 2.7 65 3.2 0.2 3.7 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG01711.1 - 2.9 7.7 5.4 12 5.7 0.9 3.4 3 1 0 3 3 3 0 Leucine rich repeat Hid1 PF12722.2 EGG01712.1 - 0.05 11.2 0.5 0.064 10.9 0.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP PF00230.15 EGG01713.1 - 0.027 13.9 0.1 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Major intrinsic protein FtsX PF02687.16 EGG01713.1 - 0.034 13.9 1.0 0.059 13.1 0.7 1.4 1 0 0 1 1 1 0 FtsX-like permease family COG7 PF10191.4 EGG01714.1 - 1.4e-49 168.7 21.5 4.7e-28 97.5 0.1 3.1 2 1 1 3 3 3 3 Golgi complex component 7 (COG7) DUF1884 PF08967.5 EGG01714.1 - 0.027 14.5 0.1 0.11 12.5 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1884) SNase PF00565.12 EGG01715.1 - 1.1e-27 96.3 0.0 1.7e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ABC1 PF03109.11 EGG01716.1 - 1.1e-25 89.9 0.0 1.9e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.6 EGG01716.1 - 0.2 10.8 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Myb_DNA-bind_6 PF13921.1 EGG01717.1 - 3.5e-14 52.6 0.0 9.5e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGG01717.1 - 2.2e-13 50.0 0.0 5.5e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain eIF-5a PF01287.15 EGG01720.1 - 2.9e-23 81.5 0.1 4e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EGG01720.1 - 1.9e-05 24.2 1.0 3.5e-05 23.3 0.7 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EGG01720.1 - 0.15 11.9 0.1 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Peptidase_C65 PF10275.4 EGG01721.1 - 5.9e-50 169.8 0.0 1.8e-49 168.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EGG01721.1 - 0.00015 22.3 0.0 0.049 14.2 0.0 2.4 2 0 0 2 2 2 2 OTU-like cysteine protease FGGY_N PF00370.16 EGG01721.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain UCH PF00443.24 EGG01722.1 - 1.5e-47 162.0 0.0 1.8e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGG01722.1 - 2.8e-14 53.2 0.5 1.2e-13 51.2 0.4 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EGG01722.1 - 8.9e-07 28.2 0.0 2.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Histone PF00125.19 EGG01723.1 - 9.8e-06 25.6 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FANCI_HD2 PF14680.1 EGG01723.1 - 0.0094 15.0 0.1 0.0097 15.0 0.1 1.0 1 0 0 1 1 1 1 FANCI helical domain 2 Methyltransf_11 PF08241.7 EGG01724.1 - 3.2e-10 40.3 0.0 4.5e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG01724.1 - 9.4e-09 35.5 0.0 1.6e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG01724.1 - 2.1e-07 30.6 0.0 2.8e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG01724.1 - 1.9e-06 28.4 0.0 2.6e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG01724.1 - 1.6e-05 24.6 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EGG01724.1 - 6.6e-05 22.4 0.0 7.4e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 EGG01724.1 - 0.005 16.5 0.0 0.0059 16.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG01724.1 - 0.019 15.4 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EGG01724.1 - 0.022 14.7 0.0 0.032 14.2 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain D-ser_dehydrat PF14031.1 EGG01724.1 - 0.037 14.2 0.0 0.059 13.5 0.0 1.3 1 1 0 1 1 1 0 Putative serine dehydratase domain Ubie_methyltran PF01209.13 EGG01724.1 - 0.058 12.4 0.0 0.068 12.2 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Oxidored_q1 PF00361.15 EGG01725.1 - 2.1e-09 37.0 0.8 2.1e-09 37.0 0.1 1.3 2 0 0 2 2 2 1 NADH-Ubiquinone/plastoquinone (complex I), various chains ATP-synt_ab PF00006.20 EGG01727.1 - 1.6e-61 207.5 0.0 2.5e-61 206.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGG01727.1 - 9.7e-25 87.2 0.1 1.6e-24 86.5 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGG01727.1 - 4e-24 84.6 1.6 8.1e-24 83.6 1.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Arch_ATPase PF01637.13 EGG01727.1 - 0.0042 16.8 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase KaiC PF06745.8 EGG01727.1 - 0.0073 15.4 0.1 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 KaiC MobB PF03205.9 EGG01727.1 - 0.015 15.0 0.1 1.8 8.3 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EGG01727.1 - 0.019 14.6 0.1 0.046 13.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Peptidase_M17_N PF02789.12 EGG01727.1 - 0.021 14.5 0.0 0.065 12.9 0.0 1.8 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain AAA_22 PF13401.1 EGG01727.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGG01727.1 - 0.056 12.8 0.0 0.13 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGG01727.1 - 0.085 11.6 0.1 0.2 10.4 0.1 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EGG01727.1 - 0.11 12.5 0.4 0.36 10.7 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EGG01727.1 - 0.14 11.3 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 F-box-like PF12937.2 EGG01728.1 - 0.00057 19.5 0.3 0.0015 18.2 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGG01728.1 - 0.3 10.7 2.7 3.6 7.3 0.1 3.2 3 0 0 3 3 3 0 F-box domain DUF3324 PF11797.3 EGG01731.1 - 0.06 13.0 0.2 0.094 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) CMAS PF02353.15 EGG01734.1 - 2.6e-20 72.6 0.0 1.3e-16 60.4 0.0 2.2 1 1 1 2 2 2 2 Mycolic acid cyclopropane synthetase DUF4218 PF13960.1 EGG01735.1 - 0.00056 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) RRM_1 PF00076.17 EGG01736.1 - 2.1e-59 197.0 0.1 2e-18 65.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG01736.1 - 1.1e-46 156.6 0.0 1.2e-14 54.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG01736.1 - 4e-30 103.4 0.0 2.2e-07 30.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0122 PF04297.9 EGG01736.1 - 0.0056 16.6 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like Nup35_RRM_2 PF14605.1 EGG01736.1 - 0.019 14.6 0.0 5.2 6.9 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EGG01736.1 - 0.048 13.4 0.2 20 5.0 0.0 3.7 3 1 0 3 3 3 0 Limkain b1 Trs65 PF12735.2 EGG01737.1 - 0.07 12.4 2.6 0.079 12.2 1.8 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 PspA_IM30 PF04012.7 EGG01740.1 - 0.013 14.8 1.1 0.025 13.9 0.7 1.5 1 0 0 1 1 1 0 PspA/IM30 family zf-TRM13_CCCH PF11722.3 EGG01743.1 - 0.0052 16.1 0.6 20 4.6 0.0 3.1 3 0 0 3 3 3 3 CCCH zinc finger in TRM13 protein Pax7 PF12360.3 EGG01743.1 - 0.075 13.3 1.0 24 5.3 0.0 3.0 1 1 2 3 3 3 0 Paired box protein 7 YpM PF09144.5 EGG01743.1 - 0.12 12.2 2.8 0.3 11.0 0.8 1.9 1 1 1 2 2 2 0 Yersinia pseudotuberculosis mitogen YL1_C PF08265.6 EGG01743.1 - 0.16 11.5 0.3 27 4.4 0.0 3.1 3 0 0 3 3 3 0 YL1 nuclear protein C-terminal domain Med3 PF11593.3 EGG01744.1 - 0.15 11.3 8.7 0.013 14.7 2.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Mucin PF01456.12 EGG01744.1 - 7.5 6.3 14.1 27 4.5 9.8 1.9 1 0 0 1 1 1 0 Mucin-like glycoprotein RhoGAP PF00620.22 EGG01745.1 - 2.1e-14 53.3 0.1 3.4e-07 29.9 0.0 2.1 1 1 1 2 2 2 2 RhoGAP domain DUF1952 PF09189.5 EGG01745.1 - 0.071 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) API5 PF05918.6 EGG01746.1 - 1.2 7.5 2.5 1.7 7.0 1.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Pro_isomerase PF00160.16 EGG01749.1 - 7.1e-31 107.5 0.3 7.7e-31 107.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CK1gamma_C PF12605.3 EGG01751.1 - 0.15 12.6 2.8 0.32 11.5 1.8 1.7 1 1 0 1 1 1 0 Casein kinase 1 gamma C terminal Polysacc_deac_1 PF01522.16 EGG01752.1 - 4e-27 94.3 0.0 2.3e-26 91.8 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGG01752.1 - 1.4e-06 27.4 0.0 2.7e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 Rsbr_N PF08678.5 EGG01752.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Rsbr N terminal DUF727 PF05303.7 EGG01752.1 - 0.078 12.7 0.8 7.6 6.3 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF727) NPV_P10 PF05531.7 EGG01756.1 - 0.00076 19.6 4.5 0.92 9.8 0.2 3.4 3 0 0 3 3 3 2 Nucleopolyhedrovirus P10 protein SH3_8 PF13457.1 EGG01756.1 - 0.072 13.2 0.1 14 5.9 0.0 2.4 2 0 0 2 2 2 0 SH3-like domain FlaC_arch PF05377.6 EGG01756.1 - 0.17 11.7 5.7 0.22 11.4 0.1 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Pex24p PF06398.6 EGG01756.1 - 0.23 10.1 1.0 0.42 9.3 0.1 1.9 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Syntaxin PF00804.20 EGG01756.1 - 0.3 11.2 17.1 0.84 9.8 0.4 3.7 2 2 1 3 3 3 0 Syntaxin ADIP PF11559.3 EGG01756.1 - 0.37 10.6 22.5 4.3 7.2 2.9 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 EGG01756.1 - 0.64 9.9 5.6 23 4.9 0.1 3.5 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Spore_II_R PF09551.5 EGG01756.1 - 0.88 9.6 9.3 2.1 8.3 0.9 3.0 1 1 2 3 3 3 0 Stage II sporulation protein R (spore_II_R) CPSase_L_D3 PF02787.14 EGG01756.1 - 1.2 8.8 4.7 2.6 7.8 0.1 2.8 2 1 1 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DASH_Hsk3 PF08227.6 EGG01756.1 - 1.4 9.1 5.6 1.4 9.1 0.3 3.2 3 1 0 3 3 3 0 DASH complex subunit Hsk3 like DUF1664 PF07889.7 EGG01756.1 - 1.6 8.5 13.2 3 7.6 0.6 3.9 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) CorA PF01544.13 EGG01756.1 - 1.7 7.6 8.1 0.24 10.4 0.4 2.5 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein Fzo_mitofusin PF04799.8 EGG01756.1 - 3.4 7.0 12.3 0.35 10.2 1.3 3.0 2 1 1 3 3 3 0 fzo-like conserved region ORF6C PF10552.4 EGG01756.1 - 3.6 7.3 14.5 4.5 7.0 0.2 3.7 2 2 1 3 3 3 0 ORF6C domain FlxA PF14282.1 EGG01756.1 - 3.8 7.4 19.7 1.8 8.5 2.0 4.2 3 2 0 3 3 3 0 FlxA-like protein Tropomyosin_1 PF12718.2 EGG01756.1 - 5.1 6.9 21.8 0.03 14.1 3.0 3.1 1 1 2 3 3 2 0 Tropomyosin like COG2 PF06148.6 EGG01756.1 - 6.5 6.6 12.2 0.22 11.3 0.5 3.2 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 XkdW PF09636.5 EGG01756.1 - 8.7 6.2 6.9 36 4.2 0.6 3.1 1 1 3 4 4 4 0 XkdW protein MCLC PF05934.6 EGG01758.1 - 0.19 10.0 2.3 0.27 9.5 1.6 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) CHASE3 PF05227.8 EGG01760.1 - 0.0059 16.2 4.1 0.019 14.6 0.0 3.5 3 1 0 3 3 3 1 CHASE3 domain BLYB PF05289.6 EGG01760.1 - 0.016 15.0 11.1 7.3 6.4 0.1 5.5 3 1 3 6 6 6 0 Borrelia hemolysin accessory protein SeleniumBinding PF11524.3 EGG01760.1 - 0.13 12.4 0.1 73 3.6 0.0 4.0 2 1 2 4 4 4 0 Selenium binding protein MCPsignal PF00015.16 EGG01760.1 - 6.6 6.2 9.6 0.83 9.1 1.2 3.0 2 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2763 PF10961.3 EGG01762.1 - 1.6 9.1 10.2 0.22 11.9 4.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Gly-rich_Ago1 PF12764.2 EGG01762.1 - 7.2 7.3 8.9 16 6.1 6.2 1.6 1 0 0 1 1 1 0 Glycine-rich region of argonaut Anp1 PF03452.9 EGG01764.1 - 0.1 11.7 4.5 0.23 10.5 3.1 1.6 1 0 0 1 1 1 0 Anp1 Tmemb_170 PF10190.4 EGG01767.1 - 0.18 11.8 1.8 0.37 10.8 1.2 1.6 1 0 0 1 1 1 0 Putative transmembrane protein 170 Cgr1 PF03879.9 EGG01769.1 - 3.9e-19 68.8 18.0 4.4e-19 68.6 12.5 1.0 1 0 0 1 1 1 1 Cgr1 family DUF1690 PF07956.6 EGG01769.1 - 0.013 15.5 7.9 0.014 15.3 5.5 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Cas_GSU0054 PF09609.5 EGG01769.1 - 0.033 13.0 0.2 0.038 12.8 0.2 1.0 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) DUF4071 PF13281.1 EGG01769.1 - 0.059 12.2 6.3 0.066 12.0 4.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) CAF-1_p150 PF11600.3 EGG01769.1 - 0.27 10.5 22.9 0.49 9.7 15.9 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal T5orf172 PF10544.4 EGG01769.1 - 0.49 10.8 2.8 0.68 10.3 1.8 1.5 1 1 0 1 1 1 0 T5orf172 domain DNA_repr_REX1B PF14966.1 EGG01769.1 - 0.66 10.3 6.0 1.2 9.5 4.1 1.6 1 1 0 1 1 1 0 DNA repair REX1-B DUF4337 PF14235.1 EGG01769.1 - 0.67 9.7 7.7 0.82 9.4 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2058 PF09831.4 EGG01769.1 - 2.9 7.7 12.1 3.6 7.4 8.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) PGC7_Stella PF15549.1 EGG01769.1 - 3.7 7.5 10.1 5.2 7.0 7.0 1.3 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain PTPlike_phytase PF14566.1 EGG01769.1 - 6.4 6.8 7.9 77 3.3 5.5 2.0 1 1 0 1 1 1 0 Inositol hexakisphosphate Prp19_bind PF06991.6 EGG01769.1 - 6.7 5.8 16.3 17 4.5 11.3 1.6 1 1 0 1 1 1 0 Splicing factor, Prp19-binding domain Atrophin-1 PF03154.10 EGG01769.1 - 6.8 4.6 9.0 7.7 4.5 6.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family Alpha_kinase PF02816.13 EGG01772.1 - 3.2e-13 49.7 0.0 5.6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family GHL1-3 PF11308.3 EGG01773.1 - 0.087 12.1 1.1 0.086 12.1 0.7 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 MMPL PF03176.10 EGG01773.1 - 0.14 10.8 1.1 0.15 10.7 0.8 1.1 1 0 0 1 1 1 0 MMPL family Dsh_C PF12316.3 EGG01773.1 - 0.33 11.0 13.7 0.36 10.9 9.5 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal FAM75 PF14650.1 EGG01773.1 - 1.3 8.2 14.3 1.6 8.0 9.9 1.0 1 0 0 1 1 1 0 FAM75 family Chs3p PF12271.3 EGG01774.1 - 4.4e-115 383.6 17.3 5.1e-115 383.4 12.0 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit F-box-like PF12937.2 EGG01775.1 - 0.032 13.9 0.0 0.082 12.6 0.0 1.7 1 1 0 1 1 1 0 F-box-like zf-DNL PF05180.7 EGG01775.1 - 0.041 13.6 0.3 0.097 12.4 0.2 1.6 1 0 0 1 1 1 0 DNL zinc finger DUF1845 PF08900.6 EGG01776.1 - 0.034 13.4 0.4 0.082 12.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1845) TrkA_N PF02254.13 EGG01776.1 - 0.29 11.1 4.3 2.7 8.0 0.2 2.8 2 0 0 2 2 2 0 TrkA-N domain Lyase_8_N PF08124.6 EGG01779.1 - 0.1 11.4 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain ABC_tran_2 PF12848.2 EGG01780.1 - 0.0016 18.2 5.3 0.0047 16.7 3.7 1.8 1 0 0 1 1 1 1 ABC transporter Allexi_40kDa PF05549.6 EGG01780.1 - 1.2 8.3 4.1 2 7.6 2.9 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Fe-S_biosyn PF01521.15 EGG01781.1 - 8.7e-10 38.5 0.0 9.6e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Prok-RING_1 PF14446.1 EGG01785.1 - 0.029 14.0 0.2 0.081 12.6 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ribosomal_L3 PF00297.17 EGG01786.1 - 2.2e-120 400.9 10.8 2.7e-120 400.6 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Bac_rhamnosid_N PF08531.5 EGG01786.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Luteo_coat PF00894.13 EGG01786.1 - 0.06 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Luteovirus coat protein Pam16 PF03656.8 EGG01787.1 - 2.3e-15 56.5 1.2 5.3e-15 55.3 0.9 1.5 1 1 0 1 1 1 1 Pam16 DUF830 PF05708.7 EGG01788.1 - 0.0099 15.8 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 1 Orthopoxvirus protein of unknown function (DUF830) BAH PF01426.13 EGG01789.1 - 2.5e-13 49.8 0.1 4.8e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 BAH domain Peptidase_C25_C PF03785.9 EGG01791.1 - 1.1e-05 25.1 1.9 0.71 9.7 0.1 3.2 3 0 0 3 3 3 2 Peptidase family C25, C terminal ig-like domain CLU PF13236.1 EGG01791.1 - 0.0028 17.0 0.0 11 5.3 0.0 3.1 3 0 0 3 3 3 1 Clustered mitochondria Subtilosin_A PF11420.3 EGG01791.1 - 0.012 15.6 3.1 16 5.5 0.0 4.1 3 0 0 3 3 3 0 Bacteriocin subtilosin A Antimicrobial17 PF08129.6 EGG01791.1 - 0.054 13.2 0.3 67 3.3 0.0 3.1 3 0 0 3 3 3 0 Alpha/beta enterocin family Zn_clus PF00172.13 EGG01791.1 - 0.063 13.1 1.9 47 3.9 0.0 3.4 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Viral_cys_rich PF08008.7 EGG01791.1 - 0.12 11.9 6.8 16 5.1 0.2 3.8 4 0 0 4 4 4 0 Viral cysteine rich TraA PF05513.6 EGG01791.1 - 0.17 12.0 0.9 3.5 7.7 0.1 2.8 3 0 0 3 3 3 0 TraA Kunitz_BPTI PF00014.18 EGG01794.1 - 0.017 15.3 0.5 0.065 13.4 0.0 2.2 2 0 0 2 2 2 0 Kunitz/Bovine pancreatic trypsin inhibitor domain NAD_binding_1 PF00175.16 EGG01795.1 - 8e-24 84.3 0.0 1.5e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGG01795.1 - 3.2e-16 59.2 0.0 2.1e-15 56.6 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGG01795.1 - 4.8e-05 23.3 0.0 0.0007 19.5 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Peroxin-3 PF04882.7 EGG01796.1 - 6.2e-95 318.4 0.0 7.2e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 CBM_19 PF03427.8 EGG01798.1 - 0.00038 20.1 0.8 0.00038 20.1 0.5 2.2 2 0 0 2 2 2 1 Carbohydrate binding domain (family 19) Ribosomal_S14 PF00253.16 EGG01800.1 - 3e-15 55.3 5.4 3.2e-15 55.2 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Toxin_17 PF08086.6 EGG01800.1 - 0.77 9.8 8.1 0.19 11.8 2.1 2.0 1 1 1 2 2 2 0 Ergtoxin family zf-CCHC PF00098.18 EGG01803.1 - 3.9e-05 23.3 0.9 7.5e-05 22.4 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4599 PF15371.1 EGG01805.1 - 0.029 14.4 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) LRR_8 PF13855.1 EGG01805.1 - 0.37 10.5 5.5 6.5 6.5 0.0 3.6 5 0 0 5 5 5 0 Leucine rich repeat MCM PF00493.18 EGG01806.1 - 9.2e-13 47.6 0.7 7.5e-08 31.5 0.1 2.0 1 1 1 2 2 2 2 MCM2/3/5 family Sel1 PF08238.7 EGG01807.1 - 3.1e-25 88.0 10.2 6.3e-10 39.3 0.1 4.0 4 1 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 EGG01807.1 - 0.00093 18.7 4.8 0.14 11.7 1.9 2.7 2 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 EGG01807.1 - 0.0019 18.8 0.5 0.024 15.3 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGG01807.1 - 0.37 10.6 3.1 8.7 6.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Tyr-DNA_phospho PF06087.7 EGG01812.1 - 9.3e-15 54.1 0.2 2.7e-14 52.6 0.2 1.6 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase DUF1870 PF08965.5 EGG01815.1 - 0.075 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) DPBB_1 PF03330.13 EGG01817.1 - 0.00018 21.4 0.0 0.0004 20.3 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel RhoGAP PF00620.22 EGG01819.1 - 1.7e-47 160.8 0.2 1.7e-47 160.8 0.1 2.8 4 0 0 4 4 4 1 RhoGAP domain LIM PF00412.17 EGG01819.1 - 9.5e-16 57.6 15.8 1.6e-09 37.6 4.4 3.0 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.17 EGG01819.1 - 9.3e-06 25.2 3.3 9.3e-06 25.2 2.3 4.2 2 1 3 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EGG01819.1 - 0.00027 20.5 2.1 0.00027 20.5 1.5 3.5 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 CENP-F_leu_zip PF10473.4 EGG01819.1 - 1.4 8.7 30.1 0.97 9.2 3.4 2.8 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.3 EGG01819.1 - 1.5 8.0 22.4 0.026 13.7 3.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF349 PF03993.7 EGG01819.1 - 1.5 9.0 8.2 1.9 8.7 0.0 3.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) UQ_con PF00179.21 EGG01820.1 - 1.3e-27 95.9 0.0 1.5e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGG01820.1 - 0.01 15.7 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain zf-Tim10_DDP PF02953.10 EGG01821.1 - 2.8e-22 77.7 0.5 3.2e-22 77.5 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EGG01821.1 - 0.045 13.2 0.2 0.055 12.9 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) AAA_17 PF13207.1 EGG01825.1 - 6.8e-08 33.3 0.0 1.1e-07 32.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG01825.1 - 6.4e-06 26.4 0.0 2.9e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGG01825.1 - 0.00017 21.5 0.0 0.00026 20.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGG01825.1 - 0.00065 18.8 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EGG01825.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EGG01825.1 - 0.021 14.3 0.0 0.057 12.9 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 EGG01825.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 EGG01825.1 - 0.092 11.8 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EGG01825.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EGG01825.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_S8e PF01201.17 EGG01826.1 - 1.1e-50 171.1 2.7 1.4e-50 170.8 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EGG01826.1 - 0.082 13.1 2.3 0.44 10.8 1.6 2.4 1 1 0 1 1 1 0 Small acidic protein family Sel1 PF08238.7 EGG01827.1 - 2.3e-20 72.5 6.2 8.7e-08 32.5 0.5 3.9 4 0 0 4 4 4 3 Sel1 repeat TPR_6 PF13174.1 EGG01827.1 - 0.49 10.9 3.2 13 6.5 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 EGG01829.1 - 1e-07 31.5 4.0 0.0076 16.1 0.0 4.5 4 1 0 4 4 4 2 WD domain, G-beta repeat RRM_1 PF00076.17 EGG01830.1 - 6.8e-40 134.5 0.0 4.2e-15 55.1 0.0 3.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG01830.1 - 1.5e-29 101.8 0.0 5e-11 42.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG01830.1 - 1.2e-15 57.0 0.0 6.2e-05 22.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGG01830.1 - 5.1e-07 29.5 0.0 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 EGG01830.1 - 5.6e-05 22.8 0.0 0.18 11.5 0.0 3.4 3 0 0 3 3 3 1 Limkain b1 DKCLD PF08068.7 EGG01830.1 - 0.063 13.2 0.1 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 DKCLD (NUC011) domain FNIP PF05725.7 EGG01832.1 - 0.26 11.2 4.0 10 6.1 0.0 3.3 3 0 0 3 3 3 0 FNIP Repeat LRR_8 PF13855.1 EGG01832.1 - 1.2 8.9 8.0 9.1 6.1 0.7 3.7 3 0 0 3 3 3 0 Leucine rich repeat SCHIP-1 PF10148.4 EGG01833.1 - 0.023 14.0 0.6 0.023 14.0 0.4 2.4 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 FOLN PF09289.5 EGG01835.1 - 0.092 12.5 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain DUF2077 PF09850.4 EGG01836.1 - 0.045 13.1 0.1 0.29 10.5 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) PIG-P PF08510.7 EGG01836.1 - 0.055 13.1 1.5 0.55 9.8 1.1 2.1 1 1 0 1 1 1 0 PIG-P Alpha_kinase PF02816.13 EGG01837.1 - 4.4e-15 55.8 0.0 7e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family AMP-binding PF00501.23 EGG01838.1 - 6.1e-93 311.4 0.2 7.4e-93 311.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGG01838.1 - 2.7e-21 76.3 1.1 5.8e-21 75.2 0.2 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain IMS PF00817.15 EGG01839.1 - 4.4e-41 140.1 0.0 7.1e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGG01839.1 - 6.2e-09 35.8 0.2 1.7e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EGG01839.1 - 0.00013 21.7 0.1 0.00046 20.0 0.1 2.0 1 0 0 1 1 1 1 IMS family HHH motif Pkinase PF00069.20 EGG01840.1 - 2.2e-54 184.3 0.0 2.6e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG01840.1 - 2.8e-31 108.5 0.0 2e-30 105.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG01840.1 - 1.2e-05 24.4 0.0 4.9e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGG01840.1 - 0.00085 19.1 0.1 0.086 12.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EGG01840.1 - 0.0019 17.0 0.2 0.0026 16.6 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 EGG01840.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EGG01840.1 - 0.023 14.0 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EGG01840.1 - 0.061 12.8 0.2 0.098 12.2 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EGG01840.1 - 0.095 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LIM PF00412.17 EGG01842.1 - 8.6e-25 86.5 24.0 2.2e-12 46.8 2.7 2.2 2 0 0 2 2 2 2 LIM domain vMSA PF00695.14 EGG01842.1 - 0.46 9.6 5.3 0.81 8.8 3.7 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus UPF0547 PF10571.4 EGG01842.1 - 1.4 8.6 9.5 1.1 8.9 0.9 3.0 2 2 0 2 2 2 0 Uncharacterised protein family UPF0547 Prok-RING_1 PF14446.1 EGG01842.1 - 3.6 7.3 30.8 0.13 11.9 1.6 3.9 2 2 2 4 4 4 0 Prokaryotic RING finger family 1 Glyco_hydro_15 PF00723.16 EGG01845.1 - 2.7e-71 240.4 0.4 3.2e-71 240.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DUF4414 PF14377.1 EGG01846.1 - 0.058 13.3 0.1 0.095 12.6 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) CI-B14_5a PF07347.7 EGG01846.1 - 0.18 11.5 3.0 0.33 10.7 2.1 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) TPR_1 PF00515.23 EGG01849.1 - 2e-50 166.4 19.8 6e-06 25.6 0.0 10.1 9 1 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 EGG01849.1 - 3.7e-45 148.2 15.5 1.6e-05 24.4 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.1 EGG01849.1 - 2e-43 145.8 19.8 3.9e-11 42.4 1.6 6.5 2 2 5 8 8 8 8 TPR repeat TPR_8 PF13181.1 EGG01849.1 - 2.4e-37 123.8 10.1 7.2e-05 22.2 0.4 9.3 7 1 2 9 9 9 8 Tetratricopeptide repeat TPR_14 PF13428.1 EGG01849.1 - 6.9e-32 107.0 3.7 0.00098 19.5 0.0 9.6 3 3 7 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 EGG01849.1 - 2e-29 101.5 2.2 2.8e-07 31.0 0.1 5.8 4 1 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGG01849.1 - 3.3e-27 94.2 21.1 3.6e-06 26.8 1.2 7.7 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 EGG01849.1 - 5e-25 85.5 12.7 2.8e-05 23.9 0.1 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 EGG01849.1 - 1.1e-23 83.2 4.9 9.7e-06 25.8 0.0 7.0 4 2 2 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGG01849.1 - 7.2e-21 73.1 10.7 0.01 16.2 0.0 9.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGG01849.1 - 6e-20 69.4 18.6 0.0021 17.6 0.0 9.9 8 3 1 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 EGG01849.1 - 4.1e-14 52.1 2.8 0.018 14.8 0.0 6.3 2 2 5 7 7 7 3 Tetratricopeptide repeat SNAP PF14938.1 EGG01849.1 - 2.9e-09 36.5 5.3 4.8e-05 22.6 0.0 4.1 2 2 2 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_15 PF13429.1 EGG01849.1 - 1.1e-08 34.5 6.3 0.032 13.3 0.1 5.2 1 1 4 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EGG01849.1 - 9.4e-07 28.8 13.7 0.012 15.7 1.0 4.7 3 3 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 EGG01849.1 - 4.6e-06 26.2 0.4 0.00054 19.4 0.0 3.3 2 2 2 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 EGG01849.1 - 1.9e-05 24.4 6.9 1.1 9.1 0.0 5.4 5 1 1 6 6 6 2 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 EGG01849.1 - 0.0012 18.8 3.1 2.7 7.9 0.2 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.3 EGG01849.1 - 0.0026 16.5 3.7 1.5 7.5 0.0 3.8 2 1 2 4 4 4 1 NMDA receptor-regulated protein 1 Tcf25 PF04910.9 EGG01849.1 - 0.008 15.1 0.3 0.17 10.7 0.0 2.9 2 1 2 4 4 4 1 Transcriptional repressor TCF25 RPN7 PF10602.4 EGG01849.1 - 0.01 15.2 7.7 5 6.4 0.0 6.0 4 2 3 7 7 7 0 26S proteasome subunit RPN7 z-alpha PF02295.12 EGG01849.1 - 0.14 11.9 0.1 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain TOM20_plant PF06552.7 EGG01849.1 - 0.27 10.8 1.2 6.7 6.2 0.1 3.6 4 2 1 5 5 4 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_5 PF12688.2 EGG01849.1 - 0.62 10.1 3.2 12 5.9 0.0 3.2 4 1 0 4 4 2 0 Tetratrico peptide repeat Fis1_TPR_C PF14853.1 EGG01849.1 - 1.4 8.8 7.1 14 5.6 0.0 4.6 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EGG01849.1 - 3.7 7.6 12.0 15 5.7 0.0 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat PMM PF03332.8 EGG01852.1 - 0.00076 19.1 0.3 0.00085 18.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase RIX1 PF08167.7 EGG01855.1 - 1.2e-08 34.8 1.9 1.2e-08 34.8 1.3 2.0 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Acetyltransf_1 PF00583.19 EGG01856.1 - 1.1e-15 57.4 0.0 1.4e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGG01856.1 - 4.7e-07 29.4 0.0 6.5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGG01856.1 - 4.4e-06 26.8 0.0 5.2e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGG01856.1 - 9.8e-06 25.6 0.0 1.8e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGG01856.1 - 0.00028 20.8 0.0 0.00041 20.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGG01856.1 - 0.0018 18.4 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGG01856.1 - 0.0035 17.2 0.1 0.0057 16.5 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain O-FucT PF10250.4 EGG01856.1 - 0.078 12.0 0.0 0.078 12.0 0.0 1.1 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase DUF489 PF04356.7 EGG01857.1 - 0.0034 16.9 4.7 0.0077 15.8 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF489) Plasmodium_Vir PF05795.6 EGG01859.1 - 0.006 15.8 2.1 0.012 14.8 1.5 1.5 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Polysacc_synt PF01943.12 EGG01859.1 - 0.075 12.2 0.1 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Chordopox_A13L PF05961.6 EGG01859.1 - 0.081 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF2104 PF09877.4 EGG01859.1 - 0.095 12.6 0.5 0.17 11.8 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) SNARE_assoc PF09335.6 EGG01859.1 - 0.098 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein EVI2A PF05399.6 EGG01859.1 - 3.7 6.7 15.6 13 4.9 10.8 1.9 1 1 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Aldose_epim PF01263.15 EGG01860.1 - 1.7e-53 181.7 0.0 2.1e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RCC1 PF00415.13 EGG01861.1 - 1.5e-20 73.0 5.6 0.00034 20.7 0.0 6.7 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EGG01861.1 - 1.2e-07 31.6 0.1 3e-05 23.9 0.0 3.1 2 1 1 3 3 3 1 BTB/POZ domain Ank_4 PF13637.1 EGG01861.1 - 4.4e-07 30.2 0.1 1.4e-06 28.6 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EGG01861.1 - 1.9e-06 27.3 0.1 5e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 EGG01861.1 - 1e-05 25.6 0.3 0.00088 19.4 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.1 EGG01861.1 - 1.1e-05 24.8 7.8 1.2e-05 24.8 0.1 3.8 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.2 EGG01861.1 - 2.2e-05 24.6 0.0 6.2e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGG01861.1 - 0.00082 19.3 0.6 0.0039 17.2 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.3 EGG01861.1 - 0.00088 18.5 0.3 0.0018 17.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) BACK PF07707.10 EGG01861.1 - 0.0063 16.3 0.1 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Apis_Csd PF11671.3 EGG01862.1 - 0.023 14.5 8.6 0.065 13.0 6.0 1.7 1 0 0 1 1 1 0 Complementary sex determiner protein LMBR1 PF04791.11 EGG01862.1 - 1.1 7.7 5.0 1.5 7.2 3.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4574 PF15141.1 EGG01862.1 - 1.2 8.9 7.7 0.81 9.4 3.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4574) Fucose_iso_N2 PF07882.7 EGG01862.1 - 7.4 6.1 10.0 15 5.1 6.9 1.5 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Alpha_kinase PF02816.13 EGG01864.1 - 4.4e-12 46.0 0.0 5.7e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Uso1_p115_head PF04869.9 EGG01864.1 - 0.058 12.1 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region Pkinase PF00069.20 EGG01867.1 - 3.6e-55 186.9 0.0 4.5e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG01867.1 - 9.4e-41 139.5 0.0 1.2e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG01867.1 - 0.00017 20.6 0.0 0.00024 20.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGG01867.1 - 0.0056 16.0 0.0 0.0077 15.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGG01867.1 - 0.042 13.5 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2654 PF10849.3 EGG01867.1 - 0.079 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) Kdo PF06293.9 EGG01867.1 - 0.16 10.9 0.2 0.26 10.3 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PBP PF01161.15 EGG01869.1 - 4.1e-22 78.6 0.1 7.5e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein AATF-Che1 PF13339.1 EGG01870.1 - 0.023 14.8 3.1 0.049 13.7 2.1 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Uds1 PF15456.1 EGG01870.1 - 0.057 13.4 6.9 0.15 12.0 1.3 2.1 2 0 0 2 2 2 0 Up-regulated During Septation I_LWEQ PF01608.12 EGG01870.1 - 0.063 13.2 1.7 0.1 12.5 1.0 1.5 1 1 0 1 1 1 0 I/LWEQ domain Rabaptin PF03528.10 EGG01870.1 - 0.069 13.0 2.3 0.11 12.4 1.6 1.4 1 0 0 1 1 1 0 Rabaptin ScpA_ScpB PF02616.9 EGG01870.1 - 0.1 12.1 5.6 0.13 11.8 3.9 1.3 1 1 0 1 1 1 0 ScpA/B protein EMP24_GP25L PF01105.19 EGG01870.1 - 1.1 8.9 4.7 3.3 7.3 3.2 1.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Peptidase_M3_N PF08439.5 EGG01870.1 - 2.6 8.1 5.6 0.66 10.0 1.0 2.1 3 0 0 3 3 3 0 Oligopeptidase F Ctr PF04145.10 EGG01871.1 - 1.7e-28 99.4 0.0 3.7e-28 98.3 0.0 1.5 1 1 0 1 1 1 1 Ctr copper transporter family DUF1053 PF06327.9 EGG01871.1 - 0.2 12.0 1.4 2.5 8.4 0.1 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1053) GCOM2 PF15328.1 EGG01873.1 - 0.14 11.9 5.6 0.11 12.2 1.5 1.9 1 1 1 2 2 2 0 Putative GRINL1B complex locus protein 2 IL17_R_N PF15037.1 EGG01873.1 - 0.18 10.7 1.2 0.19 10.7 0.9 1.1 1 0 0 1 1 1 0 Interleukin-17 receptor extracellular region DUF3357 PF11837.3 EGG01873.1 - 6.4 6.6 8.5 0.59 10.0 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DnaJ PF00226.26 EGG01874.1 - 3.8e-13 48.9 0.1 9.4e-13 47.7 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 EGG01874.1 - 8.7e-05 22.1 0.5 0.082 12.5 0.0 2.7 2 0 0 2 2 2 2 TPR repeat Drf_DAD PF06345.6 EGG01874.1 - 0.11 12.2 0.3 0.3 10.9 0.2 1.8 1 0 0 1 1 1 0 DRF Autoregulatory Domain DUF3275 PF11679.3 EGG01875.1 - 0.044 13.4 2.7 0.15 11.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) DUF4218 PF13960.1 EGG01877.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Tcp10_C PF07202.8 EGG01877.1 - 0.03 13.8 0.1 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 T-complex protein 10 C-terminus DUF1772 PF08592.6 EGG01877.1 - 0.16 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Glu-tRNAGln PF02686.10 EGG01877.1 - 0.25 11.1 2.0 1.6 8.5 0.0 2.9 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit ArfGap PF01412.13 EGG01879.1 - 3.9e-22 78.2 0.1 4.1e-22 78.1 0.1 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.5 EGG01879.1 - 0.11 12.4 1.1 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Zinc ribbon domain Flavin_Reduct PF01613.13 EGG01880.1 - 1.6e-24 86.5 0.0 2.1e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 EGG01880.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF447) Clathrin PF00637.15 EGG01882.1 - 6.1e-204 667.8 34.0 2e-33 114.9 1.2 7.3 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EGG01882.1 - 4.7e-33 112.8 0.2 1.2e-32 111.5 0.1 1.8 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EGG01882.1 - 2.8e-31 105.6 0.0 0.00079 19.5 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin-link PF09268.5 EGG01882.1 - 1.8e-12 45.9 0.1 4.3e-12 44.7 0.1 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_1 PF00515.23 EGG01882.1 - 6e-05 22.4 1.0 9.3 6.0 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EGG01882.1 - 0.00022 20.1 4.8 0.28 9.9 0.1 4.0 5 0 0 5 5 5 2 Coatomer WD associated region TPR_2 PF07719.12 EGG01882.1 - 0.0086 15.9 3.5 12 6.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG01882.1 - 0.009 15.7 7.2 0.67 9.8 0.2 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat 4HBT_3 PF13622.1 EGG01883.1 - 9.4e-33 114.0 0.0 1.2e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EGG01883.1 - 8e-23 80.5 0.3 4.5e-19 68.3 0.0 2.8 2 1 0 2 2 2 2 Acyl-CoA thioesterase Ribosomal_S13 PF00416.17 EGG01885.1 - 4.4e-39 133.2 0.7 5.4e-39 132.9 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EGG01885.1 - 0.0015 17.1 0.0 0.0016 17.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 EGG01885.1 - 0.096 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Complex1_LYR PF05347.10 EGG01886.1 - 1.1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGG01886.1 - 0.0002 21.4 0.0 0.00036 20.6 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EGG01886.1 - 0.00049 20.5 0.0 0.00066 20.1 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like XPG_N PF00752.12 EGG01887.1 - 5.2e-35 119.7 0.0 1.2e-34 118.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EGG01887.1 - 1.5e-30 105.1 0.0 3.7e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EGG01887.1 - 2.5e-06 27.6 0.0 6.9e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF3698 PF12479.3 EGG01887.1 - 2.8 8.0 5.4 4.2 7.5 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3698) UBN2_2 PF14227.1 EGG01888.1 - 0.0022 17.5 0.4 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type 6PF2K PF01591.13 EGG01889.1 - 3.1e-58 196.4 0.0 5.1e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGG01889.1 - 1.3e-22 80.5 0.0 2.3e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.5 EGG01889.1 - 4.4e-05 22.8 0.0 9.9e-05 21.6 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EGG01889.1 - 4.5e-05 23.3 0.0 8.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG01889.1 - 0.00052 20.8 0.0 0.0015 19.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain FHA PF00498.21 EGG01890.1 - 8.5e-15 54.6 0.1 5.6e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 FHA domain FIBP PF05427.6 EGG01893.1 - 0.014 14.6 1.9 0.019 14.2 1.3 1.3 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) DnaJ PF00226.26 EGG01894.1 - 9.3e-24 82.9 1.5 3.1e-23 81.2 1.0 2.0 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 EGG01894.1 - 1.6e-09 37.5 1.1 1.6e-09 37.5 0.7 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGG01894.1 - 1e-08 35.0 7.1 3.1e-08 33.5 0.5 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EGG01894.1 - 0.00015 21.8 5.9 0.14 12.5 1.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EGG01894.1 - 0.00022 21.2 12.7 0.028 14.5 0.5 3.4 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EGG01894.1 - 0.0039 17.4 3.8 1.6 9.2 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGG01894.1 - 0.36 10.8 6.6 11 6.0 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Methyltransf_33 PF10017.4 EGG01896.1 - 7.5e-37 126.0 0.0 1.5e-36 125.0 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EGG01896.1 - 7.3e-13 48.4 0.0 1.3e-07 31.3 0.1 2.3 1 1 1 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EGG01896.1 - 7.2e-06 26.3 0.1 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 DinB superfamily AAA_23 PF13476.1 EGG01897.1 - 1.8e-22 80.6 0.0 1.8e-22 80.6 0.0 7.6 2 2 3 5 5 5 1 AAA domain SbcCD_C PF13558.1 EGG01897.1 - 2.4e-11 43.3 0.2 4e-10 39.4 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EGG01897.1 - 1.8e-09 37.9 0.4 1e-05 25.6 0.1 5.1 5 0 0 5 5 5 2 AAA domain AAA_15 PF13175.1 EGG01897.1 - 0.00047 19.3 5.8 0.00047 19.3 4.0 5.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 EGG01897.1 - 0.00099 18.5 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EGG01897.1 - 0.0011 17.5 133.5 0.002 16.6 0.0 7.7 2 1 4 6 6 6 1 AAA domain ABC_tran PF00005.22 EGG01897.1 - 0.0069 16.6 0.0 0.0069 16.6 0.0 6.5 3 2 0 3 3 3 1 ABC transporter AAA_19 PF13245.1 EGG01897.1 - 0.17 11.6 0.0 0.56 9.9 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain RRM_1 PF00076.17 EGG01898.1 - 8.6e-46 153.4 1.0 8.4e-19 66.9 0.1 4.9 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG01898.1 - 1.5e-40 136.9 0.4 3.1e-16 59.0 0.0 5.0 5 0 0 5 5 5 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG01898.1 - 1.5e-20 72.8 0.5 1.6e-10 40.6 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGG01898.1 - 0.00016 21.4 0.0 0.085 12.6 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif TPR_19 PF14559.1 EGG01898.1 - 0.00036 20.7 0.3 0.014 15.6 0.7 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EGG01898.1 - 0.0006 18.7 3.1 0.32 9.8 0.5 2.7 2 1 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_16 PF13432.1 EGG01898.1 - 0.00087 19.9 1.5 0.00087 19.9 1.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGG01898.1 - 0.0017 17.9 3.0 0.34 10.5 1.1 3.6 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 EGG01898.1 - 0.002 18.6 5.6 0.85 10.4 0.1 5.0 5 1 1 6 6 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGG01898.1 - 0.0062 16.3 2.3 0.64 10.0 0.2 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF977 PF06163.6 EGG01898.1 - 0.047 13.4 0.2 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Sel1 PF08238.7 EGG01898.1 - 1 10.0 3.5 1.9 9.2 0.4 2.6 2 0 0 2 2 2 0 Sel1 repeat SET PF00856.23 EGG01899.1 - 9.8e-10 38.9 0.0 2.3e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 SET domain DUF835 PF05763.7 EGG01899.1 - 0.036 13.6 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF835) NPV_P10 PF05531.7 EGG01899.1 - 0.038 14.2 0.1 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Nop25 PF09805.4 EGG01900.1 - 0.77 9.8 9.3 0.22 11.6 0.2 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Macoilin PF09726.4 EGG01900.1 - 5.2 5.2 12.0 10 4.2 8.3 1.4 1 0 0 1 1 1 0 Transmembrane protein DUF2413 PF10310.4 EGG01900.1 - 8.2 5.1 13.1 13 4.4 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Rtf2 PF04641.7 EGG01900.1 - 8.9 5.4 11.8 17 4.4 8.2 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger GCD14 PF08704.5 EGG01901.1 - 1.1e-74 251.0 0.0 1.2e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EGG01901.1 - 3.5e-06 26.6 0.0 5.8e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGG01901.1 - 0.00015 21.3 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGG01901.1 - 0.0037 17.8 0.0 0.0052 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG01901.1 - 0.0047 16.9 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain SSXRD PF09514.5 EGG01902.1 - 0.052 12.8 0.1 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 SSXRD motif CryBP1 PF07029.6 EGG01902.1 - 0.054 13.2 0.6 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 CryBP1 protein Las1 PF04031.8 EGG01903.1 - 1.5e-31 109.1 0.0 5e-31 107.4 0.0 1.9 3 0 0 3 3 3 1 Las1-like CHAD PF05235.9 EGG01903.1 - 0.045 13.3 1.7 0.14 11.7 1.2 1.8 2 1 0 2 2 2 0 CHAD domain DnaB_bind PF10410.4 EGG01903.1 - 0.06 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Baculo_PEP_C PF04513.7 EGG01905.1 - 0.0084 15.9 0.5 0.019 14.7 0.4 1.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus WEMBL PF05701.6 EGG01905.1 - 0.0098 14.4 11.0 0.014 13.9 7.6 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Uds1 PF15456.1 EGG01905.1 - 0.026 14.5 3.9 0.026 14.5 2.7 2.1 1 1 1 2 2 2 0 Up-regulated During Septation I_LWEQ PF01608.12 EGG01905.1 - 0.026 14.4 7.6 0.032 14.1 4.1 1.9 2 0 0 2 2 2 0 I/LWEQ domain DUF1460 PF07313.7 EGG01905.1 - 0.16 11.1 1.0 0.23 10.6 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1460) AATF-Che1 PF13339.1 EGG01905.1 - 0.41 10.7 7.2 0.83 9.8 5.0 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Exonuc_VII_L PF02601.10 EGG01905.1 - 0.51 9.4 6.8 0.59 9.2 4.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 EGG01905.1 - 0.58 8.5 4.4 0.63 8.3 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EGG01905.1 - 0.79 7.5 4.0 0.82 7.4 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EcoEI_R_C PF08463.5 EGG01905.1 - 0.96 9.2 6.4 1.9 8.2 4.4 1.5 1 1 0 1 1 1 0 EcoEI R protein C-terminal MCM2_N PF12619.3 EGG01906.1 - 0.13 12.2 5.2 0.18 11.8 3.4 1.4 1 1 0 1 1 1 0 Mini-chromosome maintenance protein 2 Prenyltrans PF00432.16 EGG01907.1 - 2.1e-23 81.5 15.5 4.4e-06 26.1 0.0 6.1 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGG01907.1 - 6.9e-17 61.8 0.0 6.1e-15 55.6 0.0 2.8 3 0 0 3 3 3 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGG01907.1 - 0.0045 16.9 0.0 0.039 13.9 0.0 2.2 1 1 1 2 2 2 1 Prenyltransferase-like ThiS-like PF14453.1 EGG01908.1 - 0.071 12.9 0.2 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 ThiS-like ubiquitin Peptidase_C54 PF03416.14 EGG01910.1 - 7.4e-12 44.9 0.0 9.5e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DUF4552 PF15089.1 EGG01910.1 - 0.0061 15.4 0.4 0.0069 15.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4552) Met_10 PF02475.11 EGG01912.1 - 1.2e-08 34.7 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EGG01912.1 - 0.00024 21.1 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG01912.1 - 0.008 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ribonuclease_3 PF00636.21 EGG01913.1 - 4.8e-10 39.8 0.6 0.0013 19.1 0.0 3.8 3 1 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGG01913.1 - 8.6e-08 32.1 0.1 0.0089 15.9 0.0 3.1 2 1 0 2 2 2 2 Ribonuclease-III-like TM2 PF05154.11 EGG01913.1 - 0.15 12.3 0.6 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 TM2 domain Ssu72 PF04722.8 EGG01914.1 - 1.9e-77 258.9 0.0 2.3e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein AAA PF00004.24 EGG01915.1 - 6.5e-41 139.6 0.0 1.2e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGG01915.1 - 9.1e-07 29.0 0.2 0.0016 18.5 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 EGG01915.1 - 4.4e-06 26.7 0.0 9.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EGG01915.1 - 2.3e-05 23.4 0.0 3.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EGG01915.1 - 5.4e-05 22.9 0.2 0.00028 20.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGG01915.1 - 0.0001 22.3 0.1 0.00086 19.3 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EGG01915.1 - 0.0003 20.2 0.6 0.077 12.3 0.1 2.3 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EGG01915.1 - 0.00095 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EGG01915.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGG01915.1 - 0.0037 16.3 0.0 0.0061 15.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EGG01915.1 - 0.0052 16.5 0.4 0.011 15.4 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 EGG01915.1 - 0.0055 15.8 0.3 0.096 11.7 0.0 2.4 2 1 1 3 3 3 1 KaiC AAA_14 PF13173.1 EGG01915.1 - 0.0098 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG01915.1 - 0.01 16.6 0.7 0.038 14.7 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EGG01915.1 - 0.011 15.3 0.1 0.046 13.3 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EGG01915.1 - 0.013 14.2 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus NACHT PF05729.7 EGG01915.1 - 0.019 14.6 0.1 0.16 11.6 0.1 2.1 1 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 EGG01915.1 - 0.021 14.4 0.2 0.045 13.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGG01915.1 - 0.022 14.9 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 EGG01915.1 - 0.028 13.6 0.1 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.1 EGG01915.1 - 0.036 14.0 0.3 0.086 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EGG01915.1 - 0.05 13.9 0.8 0.077 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.17 EGG01915.1 - 0.054 12.3 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.21 EGG01915.1 - 0.059 12.8 0.1 0.23 10.9 0.0 1.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_33 PF13671.1 EGG01915.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGG01915.1 - 0.075 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EGG01915.1 - 0.085 11.8 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 EGG01915.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain UBX PF00789.15 EGG01916.1 - 1.7e-10 40.8 0.2 3.3e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 UBX domain AflR PF08493.5 EGG01916.1 - 1.4 7.9 7.8 2.4 7.1 5.4 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein Thioredoxin PF00085.15 EGG01917.1 - 1.2e-23 82.7 0.0 2.8e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin ERp29 PF07749.7 EGG01917.1 - 2e-17 63.5 0.2 2e-17 63.5 0.1 2.3 3 0 0 3 3 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EGG01917.1 - 3.3e-05 24.0 1.7 0.00016 21.8 0.0 2.7 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGG01917.1 - 0.0015 18.5 0.2 0.19 11.8 0.0 3.1 2 1 1 3 3 3 1 Thioredoxin-like LEA_1 PF03760.10 EGG01917.1 - 0.037 14.1 3.7 0.037 14.1 2.6 2.5 2 1 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 DUF883 PF05957.8 EGG01917.1 - 0.25 11.7 3.9 0.79 10.1 1.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EGG01917.1 - 7 7.1 10.8 1.4e+02 2.9 7.5 2.5 1 1 0 1 1 1 0 YtxH-like protein PAT1 PF09770.4 EGG01920.1 - 1.6e-149 499.7 24.5 6.4e-149 497.7 17.0 1.7 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 KRAB PF01352.22 EGG01920.1 - 0.4 10.1 1.6 1 8.8 1.1 1.7 1 0 0 1 1 1 0 KRAB box Phage_T4_Gp30_7 PF06919.6 EGG01923.1 - 0.077 12.9 0.3 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 Phage Gp30.7 protein Cyclin_N PF00134.18 EGG01924.1 - 1.9e-05 24.2 0.0 3.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Aconitase PF00330.15 EGG01925.1 - 1.5e-182 607.2 0.0 1.8e-182 607.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGG01925.1 - 6.3e-40 136.3 0.0 1.1e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ustilago_mating PF05722.7 EGG01926.1 - 0.06 12.6 5.4 0.088 12.1 3.8 1.3 1 0 0 1 1 1 0 Ustilago B locus mating-type protein DUF3678 PF12435.3 EGG01926.1 - 1 9.0 4.5 2.8 7.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) CarbpepA_inh PF02977.10 EGG01927.1 - 0.42 10.2 3.7 5.1 6.7 0.1 2.6 2 1 0 2 2 2 0 Carboxypeptidase A inhibitor F-box PF00646.28 EGG01930.1 - 0.12 12.0 2.3 2.8 7.7 0.2 2.9 2 0 0 2 2 2 0 F-box domain DHBP_synthase PF00926.14 EGG01931.1 - 3.2e-77 258.1 0.0 3.7e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase SRR1 PF07985.7 EGG01933.1 - 2.6e-05 24.0 0.0 0.017 15.0 0.0 2.6 2 1 0 2 2 2 2 SRR1 E1-E2_ATPase PF00122.15 EGG01935.1 - 9.3e-59 198.2 0.7 9.3e-59 198.2 0.5 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGG01935.1 - 3.8e-22 79.7 2.6 4.3e-22 79.5 0.9 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGG01935.1 - 1.1e-14 55.0 0.3 7e-14 52.4 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGG01935.1 - 4.1e-13 48.5 0.1 1e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGG01935.1 - 0.00027 20.5 0.0 0.00062 19.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGG01935.1 - 0.064 13.2 0.1 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Mon1 PF03164.9 EGG01936.1 - 2.8e-98 329.2 0.0 3.4e-98 328.9 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 GATA PF00320.22 EGG01938.1 - 4.5e-11 41.9 3.2 9.4e-11 40.8 2.2 1.5 1 0 0 1 1 1 1 GATA zinc finger CMAS PF02353.15 EGG01939.1 - 2.7e-64 216.8 0.0 7.9e-64 215.3 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EGG01939.1 - 1.1e-08 35.6 0.0 3e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG01939.1 - 4.3e-07 29.7 0.0 1.3e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG01939.1 - 5.1e-06 26.8 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG01939.1 - 5.7e-05 23.5 0.0 0.00028 21.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG01939.1 - 9.4e-05 22.0 0.0 0.00021 20.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG01939.1 - 0.0016 18.4 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EGG01939.1 - 0.013 16.3 0.0 0.038 14.8 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGG01939.1 - 0.042 14.2 0.0 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.14 EGG01939.1 - 0.05 13.1 0.1 0.17 11.4 0.0 1.7 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) KaiC PF06745.8 EGG01939.1 - 0.07 12.2 0.0 0.56 9.2 0.0 2.1 2 0 0 2 2 2 0 KaiC GPI-anchored PF10342.4 EGG01941.1 - 5.4e-13 49.2 1.1 5.4e-13 49.2 0.8 1.8 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FAD_binding_8 PF08022.7 EGG01941.1 - 0.058 13.2 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain DUF1295 PF06966.7 EGG01942.1 - 1.8e-49 168.1 0.3 2.6e-49 167.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EGG01942.1 - 9e-06 25.8 0.3 3.7e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EGG01942.1 - 0.0003 20.8 1.3 0.00065 19.7 0.0 2.3 2 1 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 EGG01942.1 - 0.00042 20.0 0.0 0.00072 19.3 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Peptidase_S10 PF00450.17 EGG01943.1 - 5.6e-101 338.7 0.8 6.7e-101 338.4 0.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Asp PF00026.18 EGG01944.1 - 7.8e-61 206.0 2.5 9.7e-61 205.7 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG01944.1 - 1.4e-06 28.4 0.0 4.5e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal JAB PF01398.16 EGG01945.1 - 4.6e-06 26.3 0.0 6.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGG01945.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function MitMem_reg PF13012.1 EGG01946.1 - 6.8e-11 42.2 0.3 3.1e-10 40.1 0.2 1.8 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function Asp PF00026.18 EGG01947.1 - 6.7e-62 209.5 10.1 8.8e-62 209.1 7.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG01947.1 - 2.2e-09 37.4 6.9 2.2e-09 37.4 3.1 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGG01947.1 - 1.2e-05 25.7 4.3 0.61 10.6 0.1 3.9 2 2 2 4 4 4 3 Aspartyl protease Sec1 PF00995.18 EGG01948.1 - 1.9e-145 485.7 0.1 2.3e-145 485.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CD20 PF04103.10 EGG01950.1 - 0.056 13.3 0.8 0.14 12.1 0.6 1.7 1 1 0 1 1 1 0 CD20-like family O-FucT PF10250.4 EGG01951.1 - 2.6e-09 36.6 0.1 5.3e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Amidohydro_1 PF01979.15 EGG01952.1 - 2.8e-56 191.5 1.0 3.7e-56 191.1 0.7 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EGG01952.1 - 3.2e-56 188.6 2.3 6.5e-56 187.6 1.6 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 EGG01952.1 - 5.3e-35 119.4 0.1 1.4e-34 118.0 0.1 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.15 EGG01952.1 - 1e-34 118.3 0.0 1.4e-33 114.6 0.0 2.5 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_5 PF13594.1 EGG01952.1 - 2.8e-08 33.4 2.8 8.7e-08 31.8 2.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EGG01952.1 - 0.014 15.4 0.1 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 Amidohydrolase APG9 PF04109.11 EGG01953.1 - 1.8e-148 494.4 1.2 2.2e-148 494.0 0.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 TPT PF03151.11 EGG01955.1 - 2.3e-19 69.5 9.9 2.3e-19 69.5 6.9 2.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family Rax2 PF12768.2 EGG01955.1 - 0.47 9.6 7.5 4.1 6.5 0.1 3.2 3 0 0 3 3 3 0 Cortical protein marker for cell polarity DUF1118 PF06549.7 EGG01955.1 - 0.5 10.5 12.9 0.1 12.7 2.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1118) RNase_P_Rpp14 PF01900.14 EGG01957.1 - 3.3e-27 94.4 0.3 4.3e-27 94.1 0.2 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family IGR PF09597.5 EGG01958.1 - 3.6e-10 39.5 1.3 1.3e-09 37.7 0.1 2.3 3 0 0 3 3 3 1 IGR protein motif FHA PF00498.21 EGG01959.1 - 3.4e-14 52.7 0.0 7.2e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain SAGA-Tad1 PF12767.2 EGG01959.1 - 0.59 9.7 6.3 0.75 9.4 4.4 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF566 PF04484.7 EGG01959.1 - 2.5 7.5 10.9 3.1 7.2 7.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF1777 PF08648.7 EGG01959.1 - 2.7 7.6 30.9 5.5 6.6 21.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF605 PF04652.11 EGG01959.1 - 4.1 6.6 10.1 4.7 6.4 7.0 1.1 1 0 0 1 1 1 0 Vta1 like Atg14 PF10186.4 EGG01960.1 - 0.92 8.3 21.5 2 7.2 2.0 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ALMT PF11744.3 EGG01960.1 - 1.7 7.2 4.8 3.3 6.2 3.3 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1289 PF06945.8 EGG01962.1 - 0.17 11.4 0.2 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Myc_N PF01056.13 EGG01964.1 - 0.0086 15.2 0.5 0.0086 15.2 0.4 2.2 2 1 0 2 2 2 1 Myc amino-terminal region Myc_N PF01056.13 EGG01965.1 - 0.012 14.8 0.4 0.012 14.8 0.3 2.0 2 1 1 3 3 3 0 Myc amino-terminal region CDI PF02234.14 EGG01965.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Ribosomal_L15e PF00827.12 EGG01966.1 - 3.5e-90 300.6 10.9 4.2e-90 300.4 7.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 TMEM154 PF15102.1 EGG01967.1 - 0.12 12.0 6.1 0.076 12.7 0.3 3.0 3 1 0 3 3 3 0 TMEM154 protein family Shisa PF13908.1 EGG01967.1 - 0.27 11.3 0.1 0.27 11.3 0.1 3.3 2 2 0 3 3 3 0 Wnt and FGF inhibitory regulator Glyco_hydro_31 PF01055.21 EGG01968.1 - 0.00077 18.3 0.0 0.00085 18.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4250 PF14056.1 EGG01969.1 - 0.045 13.4 0.1 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) LRR_8 PF13855.1 EGG01969.1 - 0.11 12.2 3.1 18 5.1 0.0 4.3 3 1 0 3 3 3 0 Leucine rich repeat Acetyltransf_8 PF13523.1 EGG01975.1 - 3.2e-44 150.4 0.0 4.5e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGG01975.1 - 5.7e-05 23.3 0.1 0.00038 20.6 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain bZIP_1 PF00170.16 EGG01977.1 - 0.00061 19.6 0.6 0.0011 18.8 0.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor ALMS_motif PF15309.1 EGG01977.1 - 0.018 14.8 0.6 3.2 7.5 0.3 2.3 2 0 0 2 2 2 0 ALMS motif bZIP_2 PF07716.10 EGG01977.1 - 0.43 10.4 2.2 0.79 9.5 1.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF1604 PF07713.8 EGG01978.1 - 9.6e-36 121.4 1.5 9.6e-36 121.4 1.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EGG01978.1 - 2.3e-07 30.4 0.3 6.1e-07 29.1 0.2 1.8 1 0 0 1 1 1 1 G-patch domain DEAD PF00270.24 EGG01979.1 - 5.5e-46 156.1 0.0 4.6e-45 153.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG01979.1 - 2.6e-27 94.4 0.0 7.1e-27 93.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG01979.1 - 3.8e-06 26.8 0.0 1.2e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2443 PF10398.4 EGG01979.1 - 0.003 17.2 0.2 0.0076 16.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2443) DUF1253 PF06862.7 EGG01979.1 - 0.024 13.0 0.0 0.5 8.6 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 EGG01979.1 - 0.052 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_24 PF13479.1 EGG01979.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Alginate_lyase PF05426.7 EGG01983.1 - 4.7e-14 52.3 0.1 6.9e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Alginate lyase KAT11 PF08214.6 EGG01985.1 - 2.8e-23 82.5 0.8 3.8e-18 65.6 0.0 3.1 1 1 2 3 3 3 2 Histone acetylation protein Thioredox_DsbH PF03190.10 EGG01985.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 DUF3579 PF12112.3 EGG01987.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) Tannase PF07519.6 EGG01990.1 - 7.1e-79 265.7 0.0 1e-56 192.6 0.0 2.8 2 1 0 2 2 2 2 Tannase and feruloyl esterase ThaI PF15514.1 EGG01990.1 - 0.052 12.8 0.0 3.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Restriction endonuclease ThaI Tannase PF07519.6 EGG01991.1 - 2.5e-99 333.1 0.2 3.3e-99 332.7 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase UBN2_3 PF14244.1 EGG01992.1 - 0.0052 16.3 0.0 0.009 15.5 0.0 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Tricorn_PDZ PF14685.1 EGG01993.1 - 0.09 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain PAT1 PF09770.4 EGG01993.1 - 1.8 6.7 12.8 2.8 6.0 8.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt5_N PF11942.3 EGG01993.1 - 2.1 9.0 14.8 0.84 10.2 0.7 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.1 EGG01993.1 - 7.1 7.0 8.3 52 4.2 0.1 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C3HC PF07967.8 EGG01994.1 - 3.8e-21 75.2 0.1 1.9e-17 63.2 0.0 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EGG01994.1 - 1.6e-15 56.6 0.0 2.4e-09 36.9 0.0 3.5 2 2 0 2 2 2 2 Rsm1-like BIR PF00653.16 EGG01994.1 - 0.0078 16.6 0.1 0.15 12.5 0.0 2.7 2 1 0 2 2 2 1 Inhibitor of Apoptosis domain BHD_3 PF10405.4 EGG01997.1 - 6.3e-25 86.6 0.0 1.2e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 EGG01997.1 - 2.3e-23 82.2 1.0 2.3e-23 82.2 0.7 2.4 2 1 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 EGG01997.1 - 1.6e-18 65.9 0.0 3.9e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EGG01997.1 - 6e-14 52.0 0.1 2.7e-13 50.0 0.0 2.3 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EGG01997.1 - 0.0031 17.7 0.0 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily U79_P34 PF03064.11 EGG01998.1 - 0.073 12.5 9.4 0.11 12.0 6.5 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4407 PF14362.1 EGG01998.1 - 0.23 10.3 1.7 0.27 10.1 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hex_IIIa PF02455.11 EGG01998.1 - 0.36 9.4 5.4 0.42 9.2 3.8 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF1510 PF07423.6 EGG01998.1 - 0.54 9.6 15.4 0.71 9.1 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 EGG01998.1 - 5.3 5.9 10.1 7.1 5.5 7.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ADIP PF11559.3 EGG01999.1 - 0.0077 16.1 0.8 0.012 15.5 0.6 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding IncA PF04156.9 EGG01999.1 - 0.013 15.0 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EGG01999.1 - 0.024 14.4 5.3 0.044 13.5 3.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.1 EGG01999.1 - 0.046 12.6 3.6 0.048 12.6 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.5 EGG01999.1 - 0.095 12.7 18.2 0.16 11.9 12.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Effector_1 PF04518.7 EGG01999.1 - 0.16 10.8 2.0 0.2 10.6 1.4 1.1 1 0 0 1 1 1 0 Effector from type III secretion system U79_P34 PF03064.11 EGG01999.1 - 0.33 10.4 9.9 0.45 10.0 6.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4337 PF14235.1 EGG01999.1 - 0.43 10.4 2.8 0.68 9.7 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ax_dynein_light PF10211.4 EGG01999.1 - 0.53 10.1 3.8 0.74 9.6 2.6 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Striatin PF08232.7 EGG01999.1 - 0.97 9.7 6.5 1.6 9.0 4.5 1.5 1 0 0 1 1 1 0 Striatin family CDC45 PF02724.9 EGG01999.1 - 1.2 7.0 7.8 1.4 6.8 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Bap31 PF05529.7 EGG01999.1 - 9 5.6 8.4 0.54 9.6 2.3 1.7 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Telomere_Sde2 PF13019.1 EGG02000.1 - 4.4e-43 146.7 0.3 4.4e-43 146.7 0.2 1.9 2 0 0 2 2 2 1 Telomere stability and silencing PyrI PF01948.13 EGG02000.1 - 0.85 9.6 4.4 2.5 8.2 1.2 2.6 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain SET PF00856.23 EGG02004.1 - 0.00046 20.5 0.0 0.001 19.4 0.0 1.6 1 0 0 1 1 1 1 SET domain Mito_carr PF00153.22 EGG02005.1 - 4.6e-65 215.3 0.0 3.8e-20 71.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3899 PF13038.1 EGG02005.1 - 0.042 14.0 0.1 0.069 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Exo5 PF09810.4 EGG02006.1 - 3.4e-41 141.5 0.2 2.8e-39 135.2 0.1 2.8 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease UIM PF02809.15 EGG02006.1 - 0.26 10.9 1.4 0.62 9.7 1.0 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif DnaJ PF00226.26 EGG02008.1 - 8.2e-09 35.0 2.2 9.8e-09 34.8 0.5 2.0 2 0 0 2 2 2 1 DnaJ domain DUF573 PF04504.9 EGG02008.1 - 3.3 8.0 10.1 0.44 10.8 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF573 Rtf2 PF04641.7 EGG02009.1 - 1.1e-55 188.6 12.8 2e-55 187.8 8.9 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EGG02009.1 - 2.4e-05 23.7 0.5 0.003 17.0 0.3 2.6 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF1178 PF06676.6 EGG02009.1 - 5.8 7.1 8.5 1.2 9.3 2.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) SAP PF02037.22 EGG02011.1 - 8.7e-05 21.9 2.8 8.7e-05 21.9 2.0 2.0 2 0 0 2 2 2 1 SAP domain ubiquitin PF00240.18 EGG02012.1 - 7.7e-26 89.2 0.8 8.8e-26 89.1 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGG02012.1 - 2.5e-17 62.3 1.1 2.8e-17 62.1 0.8 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EGG02012.1 - 0.0041 16.9 0.3 0.0063 16.3 0.2 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGG02012.1 - 0.0069 16.6 0.2 0.0086 16.3 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 EGG02012.1 - 0.0071 16.5 0.1 0.0071 16.5 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EGG02012.1 - 0.017 15.0 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG HGTP_anticodon2 PF12745.2 EGG02012.1 - 0.069 12.2 0.2 0.072 12.2 0.1 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs RNA_pol_Rpb2_2 PF04561.9 EGG02012.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 GPI-anchored PF10342.4 EGG02013.1 - 3.9e-13 49.7 1.3 5e-13 49.3 0.9 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_5 PF13205.1 EGG02013.1 - 0.00031 21.3 0.3 0.00039 20.9 0.2 1.1 1 0 0 1 1 1 1 Bacterial Ig-like domain FAD_binding_8 PF08022.7 EGG02013.1 - 0.00065 19.5 0.0 0.0012 18.6 0.0 1.4 1 1 0 1 1 1 1 FAD-binding domain PNGaseA PF12222.3 EGG02014.1 - 9.7e-48 163.0 0.4 1.4e-47 162.5 0.3 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Porin_O_P PF07396.6 EGG02014.1 - 0.019 13.8 0.3 0.031 13.1 0.2 1.2 1 0 0 1 1 1 0 Phosphate-selective porin O and P AAA PF00004.24 EGG02015.1 - 5.9e-44 149.4 0.0 1e-43 148.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EGG02015.1 - 2.1e-07 31.0 0.0 1.5e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGG02015.1 - 1.2e-06 28.7 0.2 5.2e-05 23.3 0.0 2.9 3 1 1 4 4 3 1 AAA ATPase domain AAA_5 PF07728.9 EGG02015.1 - 1.2e-06 28.2 0.1 4.5e-05 23.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGG02015.1 - 2.1e-06 27.8 0.0 0.00089 19.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EGG02015.1 - 4.5e-06 25.8 0.0 9e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGG02015.1 - 0.00016 21.3 0.1 0.00043 19.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 EGG02015.1 - 0.00018 20.5 0.0 0.00031 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EGG02015.1 - 0.00045 21.0 0.9 0.0012 19.6 0.2 2.3 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EGG02015.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EGG02015.1 - 0.0013 17.5 0.0 0.0023 16.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EGG02015.1 - 0.0015 17.7 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EGG02015.1 - 0.0016 18.3 0.0 0.0042 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGG02015.1 - 0.0019 17.6 0.1 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 EGG02015.1 - 0.0019 17.8 0.3 0.0042 16.7 0.2 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGG02015.1 - 0.0022 18.1 0.0 0.0045 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EGG02015.1 - 0.0026 18.0 0.5 0.011 16.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGG02015.1 - 0.004 16.2 0.1 0.0099 14.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.17 EGG02015.1 - 0.0049 15.7 0.1 0.088 11.6 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_28 PF13521.1 EGG02015.1 - 0.0067 16.4 0.2 0.04 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGG02015.1 - 0.0072 15.7 0.2 0.044 13.1 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EGG02015.1 - 0.0072 15.9 0.1 0.024 14.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGG02015.1 - 0.0076 15.7 0.1 0.028 13.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 EGG02015.1 - 0.017 14.8 0.0 0.076 12.6 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase Parvo_NS1 PF01057.12 EGG02015.1 - 0.02 13.7 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ResIII PF04851.10 EGG02015.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 EGG02015.1 - 0.023 13.8 0.0 0.088 11.9 0.0 2.0 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 EGG02015.1 - 0.03 13.9 0.1 0.081 12.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Thymidylate_kin PF02223.12 EGG02015.1 - 0.031 13.6 0.1 0.99 8.7 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase PhoH PF02562.11 EGG02015.1 - 0.031 13.5 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.1 EGG02015.1 - 0.033 13.7 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EGG02015.1 - 0.051 13.6 0.0 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 EGG02015.1 - 0.067 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EGG02015.1 - 0.078 12.5 0.1 0.2 11.2 0.0 1.8 2 1 0 2 2 1 0 AAA domain DUF1869 PF08956.5 EGG02015.1 - 0.13 11.8 0.0 4.2 7.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1869) AAA_23 PF13476.1 EGG02015.1 - 0.67 10.2 2.8 8 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF4200 PF13863.1 EGG02015.1 - 2.8 7.9 8.7 0.12 12.3 1.7 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Maf_N PF08383.6 EGG02016.1 - 0.93 9.1 15.5 9.1 5.9 0.2 4.5 3 1 2 5 5 5 0 Maf N-terminal region Ribosomal_L19e PF01280.15 EGG02017.1 - 2e-60 202.8 11.4 2e-60 202.8 7.9 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e OmdA PF13376.1 EGG02017.1 - 0.011 15.3 0.4 0.011 15.3 0.3 2.1 1 1 1 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF3237 PF11578.3 EGG02017.1 - 0.053 12.8 0.1 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3237) B-block_TFIIIC PF04182.7 EGG02017.1 - 0.081 12.7 0.2 8.4 6.3 0.0 2.3 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Adeno_E4_34 PF04528.8 EGG02017.1 - 5.4 6.5 6.9 5.8 6.5 0.2 2.6 2 1 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region NIP_1 PF08995.5 EGG02018.1 - 0.038 14.1 1.2 0.056 13.6 0.8 1.3 1 0 0 1 1 1 0 Necrosis inducing protein-1 PITH PF06201.8 EGG02019.1 - 1.8e-26 92.7 0.0 5.5e-25 87.9 0.0 2.0 1 1 0 1 1 1 1 PITH domain Peroxin-13_N PF04088.8 EGG02021.1 - 4.4e-38 130.7 0.3 9e-38 129.7 0.2 1.5 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EGG02021.1 - 4.9e-10 38.7 0.1 1.1e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGG02021.1 - 1.2e-09 37.3 0.1 2.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGG02021.1 - 1.6e-09 37.2 0.0 3.2e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.9 EGG02021.1 - 0.0029 17.0 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region RNA_pol_Rpb1_2 PF00623.15 EGG02023.1 - 0.0019 18.2 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 CAF1A PF12253.3 EGG02024.1 - 0.058 13.5 0.3 0.07 13.2 0.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A 3HCDH_N PF02737.13 EGG02024.1 - 0.15 11.6 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_5 PF07728.9 EGG02025.1 - 0.079 12.6 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Prominin PF05478.6 EGG02026.1 - 0.019 12.5 3.3 0.025 12.1 2.3 1.1 1 0 0 1 1 1 0 Prominin Vac_Fusion PF02346.11 EGG02026.1 - 0.1 12.0 2.7 0.32 10.4 0.5 2.5 2 0 0 2 2 2 0 Chordopoxvirus fusion protein DUF4407 PF14362.1 EGG02026.1 - 0.3 9.9 3.1 0.54 9.1 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.6 EGG02026.1 - 0.92 9.4 8.3 0.16 11.8 2.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3571 PF12095.3 EGG02026.1 - 1.1 9.4 7.4 0.87 9.8 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) V_ATPase_I PF01496.14 EGG02026.1 - 2.2 6.0 7.0 3.2 5.4 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GBP_C PF02841.9 EGG02026.1 - 3.2 6.8 11.7 4.8 6.2 8.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain bZIP_1 PF00170.16 EGG02026.1 - 9 6.3 8.8 1.3 9.0 0.6 2.5 2 0 0 2 2 2 0 bZIP transcription factor TPR_16 PF13432.1 EGG02027.1 - 0.054 14.1 0.8 4.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat GPW_gp25 PF04965.9 EGG02030.1 - 0.14 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Gene 25-like lysozyme TPR_19 PF14559.1 EGG02036.1 - 1.8e-07 31.4 0.2 0.0079 16.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG02036.1 - 0.00018 21.3 3.3 0.12 12.2 0.1 4.2 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGG02036.1 - 0.00019 21.7 0.2 1.4 9.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EGG02036.1 - 0.0012 18.9 2.5 0.37 10.9 0.1 2.9 2 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EGG02036.1 - 0.0056 16.3 0.3 0.037 13.6 0.0 2.5 3 1 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 EGG02036.1 - 0.073 13.7 1.1 45 4.8 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGG02036.1 - 0.12 12.8 7.2 2.7 8.6 0.1 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat AMP-binding PF00501.23 EGG02037.1 - 4.3e-70 236.2 0.0 5.1e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGG02037.1 - 5.9e-13 49.5 0.1 5.3e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Cuticle_1 PF08140.6 EGG02037.1 - 0.024 14.4 0.2 2.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Crustacean cuticle protein repeat MgtE_N PF03448.12 EGG02038.1 - 0.059 13.6 0.0 0.071 13.4 0.0 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain Aha1_N PF09229.6 EGG02040.1 - 7.2e-21 74.4 0.1 1.1e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EGG02040.1 - 7.1e-14 51.9 0.1 2.9e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein ApoC-I PF04691.7 EGG02040.1 - 0.27 10.9 1.4 12 5.7 0.1 2.9 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) DNAPolymera_Pol PF11590.3 EGG02040.1 - 0.32 10.6 1.0 0.93 9.2 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol Glyco_transf_43 PF03360.11 EGG02041.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 43 Glyco_transf_43 PF03360.11 EGG02042.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 43 Cellulase-like PF12876.2 EGG02042.1 - 0.097 13.1 0.0 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 Sugar-binding cellulase-like IF-2B PF01008.12 EGG02043.1 - 3.2e-59 200.2 0.0 3.7e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF656 PF04920.7 EGG02043.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF656) DUF3429 PF11911.3 EGG02044.1 - 7.7e-40 136.1 8.3 9.7e-40 135.8 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) zf-C2H2 PF00096.21 EGG02045.1 - 1.1e-10 41.1 10.3 3.6e-06 26.9 2.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG02045.1 - 2.8e-08 33.6 0.8 2.8e-08 33.6 0.5 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGG02045.1 - 1.2e-07 31.5 10.6 0.0001 22.3 1.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGG02045.1 - 0.00022 21.2 7.9 0.08 13.1 0.6 2.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGG02045.1 - 0.0019 18.3 6.7 0.28 11.4 0.5 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type IBR PF01485.16 EGG02045.1 - 0.036 13.9 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 IBR domain zf-C2HC PF01530.13 EGG02045.1 - 0.16 11.7 1.0 0.44 10.3 0.7 1.8 1 0 0 1 1 1 0 Zinc finger, C2HC type zf-H2C2_5 PF13909.1 EGG02045.1 - 3.4 8.0 8.6 4.4 7.7 0.4 2.4 2 1 0 2 2 2 0 C2H2-type zinc-finger domain UBA PF00627.26 EGG02047.1 - 0.048 13.5 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Choline_kinase PF01633.15 EGG02050.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase NUDIX PF00293.23 EGG02051.1 - 8.1e-17 61.1 0.0 1.5e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PAP1 PF08601.5 EGG02051.1 - 0.0021 17.7 7.8 0.0038 16.9 5.4 1.4 1 0 0 1 1 1 1 Transcription factor PAP1 DUF2207 PF09972.4 EGG02051.1 - 0.17 10.4 0.0 2.1 6.8 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Macoilin PF09726.4 EGG02051.1 - 0.71 8.0 3.5 0.78 7.9 2.4 1.1 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 EGG02051.1 - 1.1 8.6 9.1 2.1 7.7 6.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein COesterase PF00135.23 EGG02052.1 - 3.4e-86 290.0 0.0 4.5e-86 289.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGG02052.1 - 9.3e-09 35.1 0.3 7e-08 32.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGG02052.1 - 0.00031 20.0 0.0 0.00052 19.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGG02052.1 - 0.074 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family UK PF02512.9 EGG02052.1 - 0.1 12.9 0.1 17 5.8 0.0 2.6 2 0 0 2 2 2 0 Virulence determinant Syntaxin-18_N PF10496.4 EGG02053.1 - 2.1e-11 43.4 3.0 2.1e-11 43.4 2.1 2.5 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EGG02053.1 - 0.2 11.3 2.5 0.13 11.9 0.3 1.8 2 0 0 2 2 2 0 SNARE domain DUF2718 PF10918.3 EGG02053.1 - 0.33 11.0 1.5 3.2 7.8 0.9 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2718) DUF929 PF06053.6 EGG02054.1 - 0.0046 16.0 1.7 0.78 8.7 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF929) TPP_enzyme_N PF02776.13 EGG02055.1 - 1.8e-56 190.2 0.0 3.3e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGG02055.1 - 7.2e-46 155.5 0.0 1.1e-44 151.7 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGG02055.1 - 1.1e-37 128.9 0.2 2.6e-37 127.6 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain PFU PF09070.6 EGG02056.1 - 1.2e-40 138.1 0.1 2.2e-40 137.2 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EGG02056.1 - 9.6e-39 129.9 12.7 4.2e-08 32.7 0.0 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EGG02056.1 - 0.014 13.6 2.0 0.2 9.7 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 FBPase PF00316.15 EGG02057.1 - 1.3e-130 435.0 0.0 1.4e-130 434.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EGG02057.1 - 0.0039 16.5 0.1 0.0073 15.6 0.0 1.4 2 0 0 2 2 2 1 Inositol monophosphatase family ABC_tran PF00005.22 EGG02059.1 - 0.063 13.5 0.3 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 ABC transporter Pneumo_att_G PF05539.6 EGG02059.1 - 0.16 11.2 12.9 0.26 10.6 8.9 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF572 PF04502.8 EGG02059.1 - 2.5 7.2 8.9 3.1 6.9 6.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Stomoxyn PF11585.3 EGG02060.1 - 6.9 6.5 5.9 4.8 7.0 0.0 2.6 3 0 0 3 3 3 0 Insect antimicrobial peptide, stomoxyn SET PF00856.23 EGG02061.1 - 0.00085 19.6 1.3 0.029 14.6 0.0 3.2 2 1 0 2 2 2 1 SET domain DUF3275 PF11679.3 EGG02061.1 - 6.5 6.3 7.0 18 4.8 4.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) SH3_9 PF14604.1 EGG02062.1 - 4.6e-05 22.9 0.1 0.00014 21.3 0.0 1.9 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGG02062.1 - 0.0055 16.1 0.1 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EGG02062.1 - 0.094 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 SH3 domain ERM PF00769.14 EGG02062.1 - 0.76 9.2 22.9 1.5 8.3 15.9 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SAPS PF04499.10 EGG02062.1 - 3.7 6.0 8.2 6.6 5.2 5.7 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MRP-L20 PF12824.2 EGG02065.1 - 5e-12 46.0 0.9 8.2e-12 45.3 0.6 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.7 EGG02065.1 - 0.013 15.1 0.2 0.047 13.3 0.1 1.8 2 0 0 2 2 2 0 HTH domain Mem_trans PF03547.13 EGG02066.1 - 3e-38 131.1 3.4 4.3e-38 130.6 2.3 1.1 1 0 0 1 1 1 1 Membrane transport protein RRM_1 PF00076.17 EGG02068.1 - 6.6e-11 41.6 0.1 9.1e-10 38.0 0.1 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG02068.1 - 1.3e-09 37.9 0.0 3.5e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Myc_N PF01056.13 EGG02068.1 - 0.079 12.1 6.3 0.2 10.8 4.3 1.6 1 0 0 1 1 1 0 Myc amino-terminal region Imm35 PF15581.1 EGG02068.1 - 0.12 12.4 1.1 0.32 11.0 0.1 2.2 2 0 0 2 2 2 0 Immunity protein 35 DUF262 PF03235.9 EGG02068.1 - 8.7 6.2 13.0 1.8 8.4 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF262 TauD PF02668.11 EGG02069.1 - 1.6e-46 159.0 0.4 2.8e-46 158.3 0.3 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HCNGP PF07818.8 EGG02069.1 - 0.28 11.2 4.7 0.64 10.0 0.1 3.0 2 1 0 2 2 2 0 HCNGP-like protein IL12p40_C PF10420.4 EGG02070.1 - 0.014 15.4 0.1 0.49 10.5 0.0 2.1 1 1 1 2 2 2 0 Cytokine interleukin-12p40 C-terminus RR_TM4-6 PF06459.7 EGG02071.1 - 0.13 12.1 7.4 0.18 11.7 5.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.10 EGG02071.1 - 0.22 10.1 7.6 0.28 9.7 5.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TAF4 PF05236.9 EGG02071.1 - 0.53 9.5 14.8 0.75 9.0 10.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Sec62 PF03839.11 EGG02071.1 - 3 7.2 11.3 4.3 6.6 7.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PRP38 PF03371.10 EGG02072.1 - 3.1e-60 202.7 0.3 3.8e-60 202.4 0.2 1.0 1 0 0 1 1 1 1 PRP38 family Mit_ribos_Mrp51 PF11709.3 EGG02073.1 - 8.2e-20 71.2 0.2 1.2e-19 70.6 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit BolA PF01722.13 EGG02074.1 - 3.6e-26 90.9 0.4 4e-26 90.7 0.3 1.0 1 0 0 1 1 1 1 BolA-like protein PQ-loop PF04193.9 EGG02075.1 - 5.4e-20 70.6 19.2 1.7e-10 40.2 4.6 3.0 2 0 0 2 2 2 2 PQ loop repeat CwfJ_C_1 PF04677.10 EGG02079.1 - 3.3e-27 94.5 0.0 5.8e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EGG02079.1 - 4.9e-22 78.2 0.1 3.2e-21 75.6 0.0 2.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 RhoGAP PF00620.22 EGG02080.1 - 2.1e-20 72.8 0.0 1.2e-19 70.3 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain zf-H2C2_2 PF13465.1 EGG02081.1 - 6.3e-24 83.0 25.6 7e-09 35.5 0.1 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGG02081.1 - 3.5e-20 71.0 29.8 1.9e-05 24.7 0.5 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG02081.1 - 6.1e-12 44.9 25.9 0.00042 20.4 0.4 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGG02081.1 - 7.3e-05 22.7 10.3 0.072 13.2 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGG02081.1 - 0.004 17.0 12.4 0.076 12.9 0.1 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 EGG02081.1 - 0.02 15.1 14.8 1.6 9.0 0.2 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EGG02081.1 - 0.037 13.6 2.7 0.054 13.1 0.2 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-TRAF PF02176.13 EGG02081.1 - 0.041 14.2 2.7 0.041 14.2 1.9 2.9 1 1 2 3 3 3 0 TRAF-type zinc finger UCR_14kD PF02271.11 EGG02082.1 - 1.6e-40 137.0 1.5 1.9e-40 136.8 1.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF1845 PF08900.6 EGG02082.1 - 0.0076 15.5 0.1 0.0085 15.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1845) Acyltransferase PF01553.16 EGG02083.1 - 1e-12 47.6 0.0 2.7e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase MT0933_antitox PF14013.1 EGG02083.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 MT0933-like antitoxin protein XK-related PF09815.4 EGG02083.1 - 0.11 11.5 0.9 4.2 6.2 0.0 2.1 2 0 0 2 2 2 0 XK-related protein DUF1460 PF07313.7 EGG02083.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) HCMVantigenic_N PF12154.3 EGG02087.1 - 0.047 13.5 0.6 0.12 12.2 0.4 1.7 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV TerB-C PF15615.1 EGG02087.1 - 0.44 10.7 4.6 0.63 10.2 3.2 1.4 1 1 0 1 1 1 0 TerB-C domain FlxA PF14282.1 EGG02087.1 - 0.53 10.2 6.4 0.061 13.2 1.4 1.6 2 0 0 2 2 2 0 FlxA-like protein Sigma70_ner PF04546.8 EGG02088.1 - 0.53 9.8 5.1 2.5 7.6 3.5 1.9 1 1 0 1 1 1 0 Sigma-70, non-essential region DUF4157 PF13699.1 EGG02089.1 - 0.069 13.2 0.0 11 6.2 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4157) CbiC PF02570.10 EGG02090.1 - 0.12 11.8 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Precorrin-8X methylmutase DUF2992 PF11208.3 EGG02090.1 - 1.4 8.7 5.8 4.3 7.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) PPP4R2 PF09184.6 EGG02097.1 - 0.44 10.0 15.8 0.87 9.0 11.0 1.4 1 0 0 1 1 1 0 PPP4R2 N2227 PF07942.7 EGG02098.1 - 1.4e-21 76.6 0.0 1.6e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein TPMT PF05724.6 EGG02098.1 - 0.025 13.9 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Hid1 PF12722.2 EGG02100.1 - 2.3 5.7 10.8 2.5 5.6 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MutS_I PF01624.15 EGG02101.1 - 0.0094 15.9 0.1 0.067 13.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain I DUF3295 PF11702.3 EGG02101.1 - 4.8 6.0 14.5 7.9 5.3 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Cwf_Cwc_15 PF04889.7 EGG02101.1 - 5 6.7 22.8 1.2 8.7 13.5 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FLO_LFY PF01698.11 EGG02101.1 - 5.1 5.8 6.6 8 5.1 4.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Trypan_PARP PF05887.6 EGG02101.1 - 5.6 6.7 18.1 0.096 12.5 5.2 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) TFIIA_gamma_N PF02268.11 EGG02104.1 - 0.05 13.1 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain Pam17 PF08566.5 EGG02105.1 - 1.3e-47 161.7 0.0 1.5e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Peptidase_M41 PF01434.13 EGG02106.1 - 8.4e-65 218.2 0.2 1.5e-64 217.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGG02106.1 - 8.1e-42 142.5 0.0 3.2e-41 140.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGG02106.1 - 2.1e-05 24.5 5.8 5e-05 23.3 0.8 3.5 2 2 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EGG02106.1 - 4.1e-05 22.7 0.0 8.4e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGG02106.1 - 7.3e-05 22.4 0.1 0.00024 20.7 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EGG02106.1 - 0.00014 22.7 0.0 0.00047 20.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EGG02106.1 - 0.00035 20.2 0.0 0.00096 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EGG02106.1 - 0.00047 18.9 0.0 0.00089 18.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 EGG02106.1 - 0.0006 19.9 5.8 0.016 15.3 0.0 3.7 4 2 2 6 6 4 1 AAA domain AAA_25 PF13481.1 EGG02106.1 - 0.001 18.4 1.2 0.022 14.1 0.2 2.7 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGG02106.1 - 0.0027 17.1 0.0 0.0057 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EGG02106.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGG02106.1 - 0.0054 16.6 0.0 0.017 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG02106.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGG02106.1 - 0.018 14.1 0.3 0.29 10.2 0.1 2.3 1 1 0 2 2 2 0 KaiC Mg_chelatase PF01078.16 EGG02106.1 - 0.021 14.0 0.0 0.045 12.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EGG02106.1 - 0.028 14.4 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EGG02106.1 - 0.039 13.0 0.1 0.085 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.9 EGG02106.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EGG02106.1 - 0.07 13.0 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EGG02106.1 - 0.17 11.5 2.1 0.98 9.0 0.1 2.8 3 0 0 3 3 3 0 NACHT domain DUF3687 PF12459.3 EGG02106.1 - 0.19 10.9 0.3 0.34 10.1 0.2 1.4 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein zf-RING_2 PF13639.1 EGG02107.1 - 1.1e-07 31.5 8.6 1.6e-07 31.0 6.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGG02107.1 - 1.6e-07 31.3 4.2 2.2e-07 30.9 2.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGG02107.1 - 0.0017 18.1 5.1 0.0029 17.3 3.5 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 EGG02107.1 - 0.0038 16.9 1.9 0.0038 16.9 1.3 2.0 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.3 EGG02107.1 - 0.0039 17.1 6.5 0.0095 15.8 4.5 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 EGG02107.1 - 0.014 15.4 7.1 0.031 14.3 4.9 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG02107.1 - 0.014 15.0 8.3 0.025 14.2 5.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EGG02107.1 - 0.034 14.2 7.6 0.099 12.7 5.4 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 EGG02107.1 - 0.71 9.9 6.3 1.5 8.9 4.4 1.6 1 1 0 1 1 1 0 RING-like domain PHD PF00628.24 EGG02107.1 - 0.78 9.4 7.0 1.6 8.4 4.8 1.7 1 1 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 EGG02107.1 - 2.6 7.6 7.1 28 4.4 5.2 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EGG02107.1 - 3.2 7.5 8.7 11 5.8 6.0 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGG02107.1 - 7.9 6.4 7.3 70 3.4 5.4 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING IF-2B PF01008.12 EGG02109.1 - 0.026 13.5 0.0 0.026 13.5 0.0 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family Ribosomal_L24e PF01246.15 EGG02110.1 - 6.1e-32 109.2 3.4 1.2e-31 108.3 2.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e HlyIII PF03006.15 EGG02111.1 - 4.2e-53 180.0 18.6 5.2e-53 179.7 12.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related NfeD PF01957.13 EGG02111.1 - 0.22 11.6 2.6 0.33 11.0 0.1 2.4 1 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF4149 PF13664.1 EGG02111.1 - 0.6 10.1 10.1 0.1 12.7 1.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Ribosomal_L13 PF00572.13 EGG02112.1 - 3.9e-33 114.2 0.0 4.2e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 WASH_WAHD PF11945.3 EGG02112.1 - 0.048 12.9 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 WAHD domain of WASH complex DUF3018 PF11455.3 EGG02113.1 - 0.89 9.5 0.0 0.89 9.5 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3018) Pex14_N PF04695.8 EGG02114.1 - 0.15 12.1 2.8 3.5 7.6 1.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FA_desaturase PF00487.19 EGG02115.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase SAYSvFN PF10260.4 EGG02115.1 - 0.25 11.1 1.7 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) DUF1616 PF07760.6 EGG02117.1 - 0.00028 20.1 0.3 0.00031 19.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) UPF0104 PF03706.8 EGG02117.1 - 0.001 18.4 0.2 0.0014 17.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) DUF202 PF02656.10 EGG02117.1 - 0.014 15.6 2.6 0.088 13.0 1.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) SdpI PF13630.1 EGG02117.1 - 0.028 14.1 3.6 0.65 9.7 0.6 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family PAP2_C PF14360.1 EGG02117.1 - 0.11 12.8 2.4 0.31 11.3 0.1 2.0 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF912 PF06024.7 EGG02117.1 - 0.79 9.8 2.7 1.3 9.1 1.6 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ATP-synt_8 PF00895.15 EGG02117.1 - 2.3 8.4 0.0 2.3 8.4 0.0 2.7 3 0 0 3 3 3 0 ATP synthase protein 8 BetaGal_dom2 PF10435.4 EGG02119.1 - 0.028 13.7 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 Pro_isomerase PF00160.16 EGG02120.1 - 4.2e-50 169.9 0.0 4.7e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cyclin_N PF00134.18 EGG02121.1 - 1.1e-16 60.5 1.3 1.2e-16 60.4 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGG02121.1 - 0.00015 21.6 4.2 0.0055 16.6 0.3 2.9 2 1 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 EGG02121.1 - 0.12 12.2 0.8 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 Transcription factor TFIIB repeat FUSC_2 PF13515.1 EGG02122.1 - 1.3e-19 70.4 11.4 1.3e-19 70.4 7.9 2.8 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 EGG02122.1 - 3.3e-14 52.3 5.3 2.1e-13 49.7 2.8 2.2 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC PF04632.7 EGG02122.1 - 7.8e-13 47.7 20.2 1.6e-11 43.3 3.2 3.8 3 1 0 3 3 3 2 Fusaric acid resistance protein family DUF2421 PF10334.4 EGG02122.1 - 5e-09 36.1 1.6 1.8e-08 34.2 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 EGG02122.1 - 0.0082 16.0 4.6 0.0082 16.0 3.2 3.1 3 1 0 3 3 3 1 Bacterial protein of unknown function (DUF939) SWIM PF04434.12 EGG02123.1 - 1.4e-07 30.8 0.2 3.1e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger PHD PF00628.24 EGG02123.1 - 0.00059 19.4 9.1 0.0014 18.3 6.3 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.1 EGG02123.1 - 0.0084 15.9 7.9 0.02 14.6 5.5 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EGG02123.1 - 0.04 13.8 7.7 0.072 13.0 3.7 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 EGG02123.1 - 0.61 10.1 8.5 1.8 8.6 5.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EGG02123.1 - 2.8 7.7 7.4 0.86 9.3 2.4 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 EGG02123.1 - 9.9 5.9 8.7 27 4.6 6.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain SWIM PF04434.12 EGG02124.1 - 5.7e-08 32.0 0.1 1.2e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_2 PF13639.1 EGG02124.1 - 0.00072 19.3 7.8 0.0019 17.9 5.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGG02124.1 - 0.0046 17.0 2.5 0.012 15.7 1.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger PHD PF00628.24 EGG02124.1 - 0.0098 15.5 8.1 0.021 14.5 5.6 1.6 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.3 EGG02124.1 - 0.012 15.5 5.0 0.012 15.5 3.5 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 EGG02124.1 - 0.072 12.7 6.2 0.15 11.7 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGG02124.1 - 0.22 11.3 4.5 0.82 9.5 3.1 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EGG02124.1 - 0.24 11.4 9.5 0.72 9.9 6.6 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG02124.1 - 3.1 7.5 14.2 0.18 11.5 6.2 1.7 2 0 0 2 2 2 0 zinc-RING finger domain SWIM PF04434.12 EGG02125.1 - 2.2e-06 26.9 0.1 4.4e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger PHD PF00628.24 EGG02125.1 - 0.00078 19.0 8.8 0.0015 18.1 6.1 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.1 EGG02125.1 - 0.0023 17.7 7.2 0.0048 16.6 5.0 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EGG02125.1 - 0.0095 15.8 4.7 0.023 14.6 3.3 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 EGG02125.1 - 0.094 12.4 5.5 0.22 11.2 3.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EGG02125.1 - 0.14 11.8 7.8 0.05 13.3 2.7 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.6 EGG02125.1 - 0.44 10.2 2.7 0.99 9.1 0.4 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-C3HC4_2 PF13923.1 EGG02125.1 - 1.4 8.9 5.5 8.6 6.4 4.1 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG02125.1 - 1.8 8.3 7.3 4.2 7.1 5.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 EGG02127.1 - 1.3e-10 40.8 8.3 1.7e-10 40.4 1.0 2.0 1 1 1 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 EGG02127.1 - 0.0052 16.0 2.3 0.0052 16.0 1.6 1.3 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 EGG02127.1 - 0.016 14.8 7.8 0.027 14.1 5.4 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 C1_3 PF07649.7 EGG02127.1 - 0.044 13.8 4.9 0.044 13.8 3.4 2.1 1 1 1 2 2 2 0 C1-like domain C1_1 PF00130.17 EGG02127.1 - 0.061 13.0 7.4 0.11 12.2 5.2 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EGG02127.1 - 8.8 5.7 9.8 3.7 6.9 0.0 2.8 2 1 1 3 3 3 0 PHD-finger zf-ribbon_3 PF13248.1 EGG02127.1 - 9.7 5.5 7.3 0.25 10.6 0.8 1.6 2 0 0 2 2 2 0 zinc-ribbon domain MOZ_SAS PF01853.13 EGG02128.1 - 3.2e-72 241.7 0.1 4.8e-72 241.1 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-met PF12874.2 EGG02128.1 - 0.034 14.3 2.3 0.071 13.3 1.6 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EGG02128.1 - 0.13 12.7 4.9 0.27 11.6 3.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DPBB_1 PF03330.13 EGG02130.1 - 1.4e-10 41.0 0.0 2.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel UPF0547 PF10571.4 EGG02130.1 - 0.0023 17.6 0.6 0.0057 16.3 0.4 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 Barwin PF00967.12 EGG02130.1 - 0.0026 17.4 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Barwin family DZR PF12773.2 EGG02130.1 - 0.038 13.8 0.8 0.1 12.4 0.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EGG02130.1 - 0.45 9.8 2.9 12 5.2 0.0 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EGG02130.1 - 3.2 7.3 7.0 20 4.8 2.5 3.1 2 1 0 2 2 2 0 zinc-ribbon domain Glyco_hydro_47 PF01532.15 EGG02131.1 - 2.4e-90 303.3 0.0 5.4e-90 302.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PTPLA PF04387.9 EGG02132.1 - 8.9e-38 129.2 6.5 9.5e-38 129.2 4.5 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA WD40 PF00400.27 EGG02133.1 - 6.1e-35 117.8 12.6 3.6e-11 42.4 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGG02133.1 - 0.0022 16.8 0.1 0.24 10.0 0.0 2.4 1 1 0 2 2 2 2 Nup133 N terminal like PQQ_3 PF13570.1 EGG02133.1 - 0.021 15.0 0.0 16 5.9 0.0 4.4 4 1 0 4 4 4 0 PQQ-like domain zf-H2C2_2 PF13465.1 EGG02134.1 - 8e-22 76.3 17.5 2.2e-08 33.9 0.1 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGG02134.1 - 9.4e-19 66.5 20.5 1.5e-06 28.1 0.1 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG02134.1 - 1.9e-11 43.4 19.0 0.0002 21.4 0.1 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGG02134.1 - 0.00048 20.1 10.6 0.22 11.7 0.3 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGG02134.1 - 0.00086 19.1 8.1 0.28 11.1 0.0 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-TRAF PF02176.13 EGG02134.1 - 0.0019 18.5 5.3 0.017 15.4 0.4 2.4 1 1 1 2 2 2 2 TRAF-type zinc finger zf-CGNR PF11706.3 EGG02134.1 - 0.081 12.4 8.4 0.61 9.6 0.1 3.7 4 0 0 4 4 4 0 CGNR zinc finger zf-C2HC_2 PF13913.1 EGG02134.1 - 0.27 10.9 3.8 3.5 7.3 0.1 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type FANCL_C PF11793.3 EGG02134.1 - 1.9 8.4 6.9 2.6 8.0 1.6 2.6 1 1 2 3 3 3 0 FANCL C-terminal domain CHORD PF04968.7 EGG02134.1 - 6.3 7.1 10.8 26 5.1 0.1 3.3 1 1 2 3 3 3 0 CHORD Pyr_excise PF03013.9 EGG02135.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.5 1 1 0 1 1 1 0 Pyrimidine dimer DNA glycosylase MAPEG PF01124.13 EGG02136.1 - 1.2e-23 83.0 2.4 1.5e-23 82.8 1.7 1.0 1 0 0 1 1 1 1 MAPEG family Adap_comp_sub PF00928.16 EGG02137.1 - 6.5e-88 294.2 0.4 9.2e-88 293.7 0.1 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGG02137.1 - 5.3e-07 29.4 0.5 9e-07 28.6 0.4 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Syja_N PF02383.13 EGG02138.1 - 5.7e-79 265.1 0.0 9.7e-79 264.4 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Ytp1 PF10355.4 EGG02139.1 - 4e-51 173.8 13.4 4e-51 173.8 9.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EGG02139.1 - 8.6e-16 57.4 4.8 8.6e-16 57.4 3.3 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 EGG02139.1 - 2.4e-06 27.4 5.2 2.4e-06 27.4 3.6 3.0 2 1 1 3 3 3 1 Eukaryotic cytochrome b561 Sedlin_N PF04628.8 EGG02140.1 - 2.8e-30 104.8 0.5 3.4e-29 101.3 0.4 2.0 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EGG02140.1 - 3.2e-06 26.8 0.1 8.5e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Sybindin-like family HMG_box PF00505.14 EGG02141.1 - 0.0015 18.7 0.1 0.0044 17.2 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGG02141.1 - 0.0054 17.0 0.2 0.0054 17.0 0.1 2.0 2 0 0 2 2 2 1 HMG-box domain Aminotran_5 PF00266.14 EGG02143.1 - 1.2e-30 106.5 0.0 6.1e-21 74.5 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V RhoGEF PF00621.15 EGG02144.1 - 2.6e-28 99.1 0.0 1.2e-27 97.0 0.0 2.0 1 1 1 2 2 2 1 RhoGEF domain FYVE PF01363.16 EGG02144.1 - 4.1e-19 68.2 12.3 8.3e-19 67.2 8.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EGG02144.1 - 7.9e-08 32.4 1.1 1.8e-07 31.2 0.0 2.3 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 EGG02144.1 - 0.03 14.5 0.0 0.15 12.3 0.0 2.3 1 0 0 1 1 1 0 Pleckstrin homology domain Phage_RpbA PF10789.4 EGG02144.1 - 0.053 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA HypA PF01155.14 EGG02144.1 - 0.36 10.5 4.2 1.6 8.4 3.0 1.9 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family LRR_6 PF13516.1 EGG02145.1 - 0.00015 21.4 30.3 0.13 12.4 0.2 9.1 11 0 0 11 11 11 3 Leucine Rich repeat LRR_8 PF13855.1 EGG02145.1 - 0.00033 20.3 20.9 0.083 12.6 0.1 5.8 4 2 2 6 6 6 4 Leucine rich repeat LRR_4 PF12799.2 EGG02145.1 - 0.064 12.9 31.8 0.26 10.9 1.0 7.0 5 3 2 7 7 7 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGG02145.1 - 0.1 12.8 23.7 3.1 8.3 0.1 9.1 10 0 0 10 10 10 0 Leucine rich repeat DnaJ PF00226.26 EGG02146.1 - 3.7e-20 71.4 3.4 4.4e-20 71.1 1.0 2.3 2 0 0 2 2 2 1 DnaJ domain Sad1_UNC PF07738.8 EGG02150.1 - 1.1e-27 96.4 0.0 1.7e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal EXOSC1 PF10447.4 EGG02161.1 - 0.12 12.2 0.0 0.67 9.9 0.0 1.9 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 WD40 PF00400.27 EGG02163.1 - 2.9e-26 90.3 12.5 7.5e-10 38.3 0.2 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EGG02163.1 - 0.017 13.2 1.2 0.037 12.1 0.0 2.0 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Lar_restr_allev PF14354.1 EGG02163.1 - 4.9 7.5 0.0 4.9 7.5 0.0 3.1 3 1 0 3 3 3 0 Restriction alleviation protein Lar CRAL_TRIO PF00650.15 EGG02165.1 - 0.04 13.4 0.1 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain Med7 PF05983.6 EGG02165.1 - 0.061 13.0 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 MED7 protein CK2S PF15011.1 EGG02166.1 - 0.036 13.8 0.0 0.039 13.7 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate Streptin-Immun PF11083.3 EGG02167.1 - 0.15 12.0 0.6 5.2 7.1 0.1 2.1 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein TRI9 PF08195.6 EGG02170.1 - 0.14 11.8 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 TRI9 protein NADHdh_A3 PF14987.1 EGG02172.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 KNOX1 PF03790.8 EGG02173.1 - 0.0018 17.5 0.1 2.7 7.4 0.0 2.7 2 0 0 2 2 2 2 KNOX1 domain PDZ_2 PF13180.1 EGG02174.1 - 3.1e-05 23.7 0.1 8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EGG02174.1 - 0.0016 18.5 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF4294 PF14127.1 EGG02174.1 - 0.098 12.2 0.5 0.22 11.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) Filaggrin PF03516.8 EGG02175.1 - 0.028 14.8 0.7 0.028 14.8 0.5 1.7 2 0 0 2 2 2 0 Filaggrin MCP_N PF05581.7 EGG02175.1 - 0.12 12.5 0.1 4.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Vibrio chemotaxis protein N terminus zf-DHHC PF01529.15 EGG02176.1 - 0.051 12.9 0.6 0.071 12.4 0.4 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase PSCyt3 PF07627.6 EGG02176.1 - 0.64 9.9 3.3 11 5.9 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1588) CENP-B_dimeris PF09026.5 EGG02181.1 - 0.72 10.1 29.5 4 7.7 13.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TFIIA PF03153.8 EGG02181.1 - 2.7 7.8 17.1 3.7 7.3 11.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NST1 PF13945.1 EGG02183.1 - 0.0023 18.0 5.2 0.0043 17.1 3.6 1.4 1 0 0 1 1 1 1 Salt tolerance down-regulator DUF1528 PF07515.6 EGG02183.1 - 0.022 14.7 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1528) DUF2456 PF10445.4 EGG02184.1 - 1.2e-17 63.6 3.1 2.3e-17 62.6 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) Ustilago_mating PF05722.7 EGG02186.1 - 0.0003 20.1 3.2 0.00046 19.6 2.2 1.2 1 0 0 1 1 1 1 Ustilago B locus mating-type protein Cohesin_HEAT PF12765.2 EGG02188.1 - 0.022 14.7 0.1 0.059 13.3 0.1 1.7 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion DUF3752 PF12572.3 EGG02189.1 - 9.3e-19 68.0 14.2 2.6e-18 66.6 5.8 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3752) PcfJ PF14284.1 EGG02189.1 - 0.17 11.3 2.0 1.6 8.2 0.1 2.2 2 0 0 2 2 2 0 PcfJ-like protein PUF PF00806.14 EGG02190.1 - 4.3e-64 208.5 7.2 4e-09 35.4 0.1 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 EGG02190.1 - 0.00055 20.1 0.0 0.55 10.5 0.0 4.4 2 1 4 6 6 6 1 Protein of unknown function DUF260 DnaB_bind PF10410.4 EGG02190.1 - 0.0045 16.9 0.5 0.3 11.1 0.0 3.2 3 1 0 4 4 4 1 DnaB-helicase binding domain of primase DASH_Dad1 PF08649.5 EGG02190.1 - 0.1 12.2 0.9 3.2 7.5 0.0 3.1 4 0 0 4 4 4 0 DASH complex subunit Dad1 Drf_GBD PF06371.8 EGG02192.1 - 0.02 14.2 0.1 0.028 13.7 0.1 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain DUF4629 PF15442.1 EGG02193.1 - 0.15 12.1 7.4 0.22 11.6 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) TATR PF03430.8 EGG02193.1 - 0.27 9.8 4.4 0.32 9.5 3.0 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator ATG22 PF11700.3 EGG02195.1 - 4.1e-112 375.1 21.6 5.2e-112 374.7 15.0 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EGG02195.1 - 1.6e-06 27.0 6.1 1.6e-06 27.0 4.2 4.3 3 2 0 4 4 4 3 Major Facilitator Superfamily SDA1 PF05285.7 EGG02198.1 - 8.7e-78 261.8 31.8 8.7e-78 261.8 22.0 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EGG02198.1 - 4.2e-09 36.5 0.1 1.2e-08 35.0 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain PPR_1 PF12854.2 EGG02199.1 - 0.35 10.3 0.8 1.5 8.3 0.1 2.1 2 0 0 2 2 2 0 PPR repeat SnoaL_2 PF12680.2 EGG02201.1 - 1.1e-05 25.7 0.0 1.5e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF1002 PF06207.6 EGG02201.1 - 0.018 14.3 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) DUF4440 PF14534.1 EGG02201.1 - 0.034 14.3 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Cation_efflux PF01545.16 EGG02203.1 - 6.1e-10 38.6 1.5 8.1e-08 31.6 0.2 2.1 2 0 0 2 2 2 2 Cation efflux family HupE_UreJ_2 PF13795.1 EGG02203.1 - 0.034 13.6 0.9 0.053 13.0 0.6 1.3 1 0 0 1 1 1 0 HupE / UreJ protein Myb_DNA-bind_2 PF08914.6 EGG02203.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Rap1 Myb domain BUD22 PF09073.5 EGG02204.1 - 0.081 11.9 9.9 0.11 11.6 6.9 1.2 1 0 0 1 1 1 0 BUD22 FYDLN_acid PF09538.5 EGG02204.1 - 0.23 12.0 11.3 0.15 12.6 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PIG-U PF06728.8 EGG02205.1 - 2.1e-81 273.7 39.0 2.6e-81 273.4 27.1 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Ank PF00023.25 EGG02208.1 - 0.016 14.9 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.1 EGG02208.1 - 0.017 15.3 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGG02208.1 - 0.025 14.7 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat zf-C2H2_jaz PF12171.3 EGG02208.1 - 0.053 13.6 0.2 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Ank_4 PF13637.1 EGG02208.1 - 0.063 13.8 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGG02208.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) KAP PF05804.7 EGG02209.1 - 0.039 11.8 0.1 0.059 11.2 0.1 1.2 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Tape_meas_lam_C PF09718.5 EGG02210.1 - 0.17 11.8 1.9 0.56 10.1 0.4 2.5 2 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DDHD PF02862.12 EGG02213.1 - 0.17 11.6 8.2 0.23 11.2 5.7 1.2 1 0 0 1 1 1 0 DDHD domain HCV_NS5a_C PF12941.2 EGG02213.1 - 0.17 11.4 2.9 0.23 11.0 2.0 1.2 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region HA2 PF04408.18 EGG02213.1 - 0.29 11.1 2.6 0.87 9.6 1.8 1.7 1 0 0 1 1 1 0 Helicase associated domain (HA2) SprA-related PF12118.3 EGG02213.1 - 0.42 9.8 13.5 0.53 9.5 9.4 1.1 1 0 0 1 1 1 0 SprA-related family DUF912 PF06024.7 EGG02213.1 - 0.47 10.5 8.5 0.14 12.2 3.8 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Suf PF05843.9 EGG02213.1 - 1 9.0 9.5 1.3 8.6 6.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RNA_pol_Rbc25 PF08292.7 EGG02215.1 - 1.1e-26 93.4 0.0 1.4e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EGG02215.1 - 5.6e-15 55.2 0.1 9.2e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Peptidase_C7 PF01830.13 EGG02221.1 - 0.78 8.8 3.9 9.8 5.2 0.8 2.2 2 0 0 2 2 2 0 Peptidase C7 family Cu-oxidase_3 PF07732.10 EGG02224.1 - 3.8e-44 149.1 6.2 3.6e-43 146.0 0.0 4.1 5 0 0 5 5 5 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG02224.1 - 3.1e-29 101.2 0.6 4.7e-24 84.4 0.1 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EGG02224.1 - 6.1e-14 52.2 0.0 6.2e-13 48.9 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase MFS_1 PF07690.11 EGG02225.1 - 1.7e-18 66.5 32.7 1.1e-17 63.8 21.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG02225.1 - 2.2e-08 33.1 25.7 2.7e-08 32.8 2.8 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter NST1 PF13945.1 EGG02226.1 - 1 9.4 9.2 0.11 12.5 2.7 2.0 2 0 0 2 2 2 0 Salt tolerance down-regulator Memo PF01875.12 EGG02227.1 - 7.9e-44 149.5 0.0 9.6e-44 149.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein MtN3_slv PF03083.11 EGG02227.1 - 0.15 11.9 0.6 0.54 10.1 0.0 2.2 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange Toxin_11 PF07473.6 EGG02228.1 - 6.7 6.6 8.1 47 3.9 0.0 4.0 4 0 0 4 4 4 0 Spasmodic peptide gm9a RVP PF00077.15 EGG02230.1 - 0.0021 17.9 0.5 0.0077 16.1 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EGG02230.1 - 0.0068 16.1 0.0 0.019 14.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EGG02230.1 - 0.0099 16.3 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease LIF_OSM PF01291.12 EGG02230.1 - 0.098 12.5 2.0 0.12 12.3 0.2 2.0 2 0 0 2 2 2 0 LIF / OSM family VHL PF01847.11 EGG02230.1 - 1.7 8.1 4.7 3.4 7.1 0.6 2.6 2 1 1 3 3 3 0 von Hippel-Lindau disease tumour suppressor protein Syntaxin_2 PF14523.1 EGG02230.1 - 8.2 6.5 16.7 7.2 6.7 7.2 3.1 1 1 2 3 3 3 0 Syntaxin-like protein VLPT PF07122.6 EGG02235.1 - 0.099 12.3 0.8 0.17 11.5 0.5 1.4 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) SNF2_N PF00176.18 EGG02236.1 - 1.1e-30 106.4 0.0 1.4e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGG02236.1 - 1.3e-07 31.2 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG02237.1 - 2.2e-10 40.2 0.0 4.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDC45 PF02724.9 EGG02245.1 - 0.59 8.0 7.0 0.79 7.6 4.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 EGG02245.1 - 2.7 7.6 11.3 4.1 7.0 7.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Adeno_E1A PF02703.9 EGG02247.1 - 2.2 7.6 6.3 2.4 7.5 3.8 1.4 1 1 0 1 1 1 0 Early E1A protein Opiods_neuropep PF01160.13 EGG02248.1 - 0.03 14.0 0.3 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide SDA1 PF05285.7 EGG02249.1 - 0.051 12.8 18.7 0.066 12.4 13.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EGG02249.1 - 0.86 7.4 20.9 0.99 7.2 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.6 EGG02249.1 - 4.5 7.0 12.9 6.2 6.6 8.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TFIIA PF03153.8 EGG02249.1 - 6.8 6.4 18.5 7.4 6.3 12.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 EGG02249.1 - 9.4 4.5 22.2 11 4.3 15.4 1.1 1 0 0 1 1 1 0 Daxx Family PGBA_C PF15437.1 EGG02250.1 - 0.14 12.3 11.1 0.22 11.6 7.7 1.3 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal zf-CCHC PF00098.18 EGG02252.1 - 0.0012 18.7 1.5 0.0056 16.5 0.6 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 EGG02252.1 - 0.076 12.5 2.0 0.12 11.8 0.3 2.2 2 0 0 2 2 2 0 Zinc knuckle UPF0181 PF03701.9 EGG02254.1 - 0.0027 16.9 0.1 0.0062 15.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0181) DUF3734 PF12536.3 EGG02254.1 - 0.011 15.8 0.5 0.034 14.2 0.4 1.9 1 0 0 1 1 1 0 Patatin phospholipase peroxidase PF00141.18 EGG02255.1 - 5.3e-30 104.5 0.0 1.2e-28 100.1 0.0 2.1 2 0 0 2 2 2 2 Peroxidase Cu-oxidase_3 PF07732.10 EGG02257.1 - 2.1e-35 121.0 8.9 1.6e-33 114.9 1.6 4.5 3 2 1 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG02257.1 - 6e-27 93.8 4.3 1.2e-23 83.1 0.0 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGG02257.1 - 5.9e-26 91.2 0.1 4e-24 85.3 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase SET PF00856.23 EGG02258.1 - 3.8e-19 69.5 4.9 4e-19 69.4 0.3 3.1 2 1 0 2 2 2 1 SET domain ATG22 PF11700.3 EGG02259.1 - 5.6e-86 288.9 23.7 6.8e-86 288.6 16.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EGG02259.1 - 1.9e-08 33.4 33.3 6.4e-07 28.4 13.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1469 PF07332.6 EGG02259.1 - 0.93 9.2 6.9 1.4 8.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Use1 PF09753.4 EGG02260.1 - 8.3e-11 41.8 1.9 7.1e-10 38.7 0.0 2.5 3 0 0 3 3 3 1 Membrane fusion protein Use1 HisKA_3 PF07730.8 EGG02260.1 - 0.0013 18.9 3.0 0.31 11.4 0.1 2.6 2 1 0 2 2 2 2 Histidine kinase GvpL_GvpF PF06386.6 EGG02260.1 - 0.038 13.5 1.0 0.074 12.6 0.4 1.6 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF U79_P34 PF03064.11 EGG02261.1 - 9.6 5.6 14.9 24 4.3 6.7 2.2 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DUF1127 PF06568.6 EGG02262.1 - 0.00012 21.4 0.4 0.00061 19.1 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1127) Pkinase PF00069.20 EGG02263.1 - 4.5e-75 252.1 0.0 5.1e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG02263.1 - 6.9e-43 146.5 0.0 8.3e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG02263.1 - 1.2e-08 34.2 0.0 4.3e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGG02263.1 - 0.001 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGG02263.1 - 0.0086 15.8 0.4 0.45 10.2 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Tat PF00539.13 EGG02264.1 - 2.9 7.5 5.3 6.7 6.4 3.7 1.6 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) Cyt-b5 PF00173.23 EGG02266.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain ATG22 PF11700.3 EGG02267.1 - 5.2e-100 335.1 21.9 5.8e-100 335.0 15.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EGG02267.1 - 1.9e-10 39.9 32.2 5.2e-08 31.9 3.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily BT1 PF03092.11 EGG02267.1 - 0.0039 15.9 4.4 0.0039 15.9 3.0 1.6 2 0 0 2 2 2 1 BT1 family YjgP_YjgQ PF03739.9 EGG02268.1 - 0.0012 17.7 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family DUF912 PF06024.7 EGG02268.1 - 0.0082 16.1 0.2 0.025 14.6 0.0 1.8 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 EGG02268.1 - 0.46 10.8 3.8 7.4 6.9 1.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Catalase PF00199.14 EGG02269.1 - 5.9e-152 505.8 0.3 6.9e-152 505.5 0.2 1.0 1 0 0 1 1 1 1 Catalase Sulfate_transp PF00916.15 EGG02270.1 - 1.2e-35 122.8 10.4 1.2e-35 122.8 7.2 2.4 1 1 1 2 2 2 1 Sulfate transporter family STAS PF01740.16 EGG02270.1 - 2.7e-11 42.9 0.1 5.3e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.24 EGG02270.1 - 5.6e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS_2 PF13466.1 EGG02270.1 - 0.00043 20.2 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain Tyrosinase PF00264.15 EGG02274.1 - 3.8e-31 108.9 7.5 7.2e-31 108.0 5.2 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase IF3_C PF00707.17 EGG02275.1 - 2.8e-07 30.1 0.2 5.6e-07 29.2 0.1 1.6 1 1 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EGG02275.1 - 0.0082 15.5 0.1 0.015 14.6 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_N PF05198.11 EGG02275.1 - 0.044 13.7 0.4 0.15 11.9 0.0 2.1 3 0 0 3 3 3 0 Translation initiation factor IF-3, N-terminal domain HORMA PF02301.13 EGG02276.1 - 5.3e-34 117.5 4.6 6.2e-34 117.3 3.2 1.0 1 0 0 1 1 1 1 HORMA domain MIP PF00230.15 EGG02278.1 - 7.2e-36 123.7 15.3 7.9e-36 123.6 10.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein Put_Phosphatase PF06888.7 EGG02282.1 - 1.2e-50 171.8 1.3 1.4e-50 171.7 0.9 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.2 EGG02282.1 - 1.1e-05 25.7 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGG02282.1 - 0.0005 20.3 0.7 0.0013 18.9 0.5 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGG02282.1 - 0.0033 17.0 0.1 0.0049 16.4 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EGG02282.1 - 0.0054 16.0 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF2608 PF11019.3 EGG02282.1 - 0.044 12.7 1.1 0.23 10.4 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2608) Z1 PF10593.4 EGG02283.1 - 0.48 9.5 4.0 0.53 9.4 2.3 1.4 1 1 0 1 1 1 0 Z1 domain Antimicrobial_6 PF08036.6 EGG02284.1 - 1 9.1 6.2 2.5 7.9 3.1 2.3 2 0 0 2 2 2 0 Diapausin family of antimicrobial peptide ORC6 PF05460.8 EGG02287.1 - 0.069 12.2 3.5 0.09 11.8 2.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) F-box PF00646.28 EGG02289.1 - 2.5e-07 30.1 2.3 5.6e-07 29.0 1.6 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGG02289.1 - 6.3e-05 22.6 0.1 0.00015 21.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EGG02289.1 - 0.0011 18.8 0.3 0.28 11.1 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Ag332 PF04671.7 EGG02289.1 - 2.4 8.0 4.8 0.5 10.2 0.8 1.8 2 0 0 2 2 2 0 Erythrocyte membrane-associated giant protein antigen 332 SPRY PF00622.23 EGG02290.1 - 8e-16 58.2 0.0 1.3e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain RCR PF12273.3 EGG02290.1 - 0.023 15.2 0.6 2 9.0 0.0 2.5 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.1 EGG02290.1 - 0.13 11.9 0.1 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family HemY_N PF07219.8 EGG02290.1 - 0.31 10.6 0.9 0.54 9.8 0.6 1.4 1 0 0 1 1 1 0 HemY protein N-terminus DUF3439 PF11921.3 EGG02294.1 - 3.6 7.3 10.3 2.9 7.6 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF2636 PF11120.3 EGG02294.1 - 8 6.0 6.4 0.98 8.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2636) Pkinase PF00069.20 EGG02295.1 - 0.0012 18.0 0.0 0.0014 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pol_alpha_B_N PF08418.5 EGG02295.1 - 0.11 12.0 1.6 0.13 11.7 1.1 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal FAP PF07174.6 EGG02295.1 - 0.28 10.4 7.7 0.3 10.3 5.3 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) FAM47 PF14642.1 EGG02295.1 - 3.8 6.7 13.8 4.8 6.3 9.5 1.1 1 0 0 1 1 1 0 FAM47 family Syja_N PF02383.13 EGG02297.1 - 1.4e-12 47.0 0.0 1.8e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EGG02298.1 - 1.1e-25 91.0 0.0 1.3e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1335 PF07056.6 EGG02298.1 - 0.025 14.3 0.1 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1335) RNA_pol_Rpb1_5 PF04998.12 EGG02301.1 - 6.7e-27 94.4 0.0 7.7e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Clr2 PF10383.4 EGG02302.1 - 0.36 10.8 1.8 0.55 10.2 1.3 1.2 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 FYDLN_acid PF09538.5 EGG02302.1 - 0.79 10.3 16.0 0.96 10.0 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) AF-4 PF05110.8 EGG02307.1 - 0.34 8.7 24.5 0.53 8.0 17.0 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Telomere_Sde2 PF13019.1 EGG02308.1 - 1.9 8.1 6.1 1.3 8.6 0.8 2.2 1 1 1 2 2 2 0 Telomere stability and silencing Mago-bind PF09282.5 EGG02311.1 - 4.8e-13 48.4 2.2 9.7e-13 47.4 1.5 1.6 1 0 0 1 1 1 1 Mago binding SspK PF08176.7 EGG02311.1 - 0.028 14.4 5.1 0.51 10.3 0.1 2.9 2 1 1 3 3 3 0 Small acid-soluble spore protein K family XRCC4 PF06632.7 EGG02311.1 - 7 5.3 12.5 0.13 11.1 3.5 1.7 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Brix PF04427.13 EGG02312.1 - 7.6e-37 126.8 0.0 1.3e-36 126.0 0.0 1.4 1 0 0 1 1 1 1 Brix domain Menin PF05053.8 EGG02312.1 - 3 5.8 5.8 4.3 5.3 4.0 1.2 1 0 0 1 1 1 0 Menin Dicty_REP PF05086.7 EGG02312.1 - 5 4.7 4.7 7 4.2 3.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SHMT PF00464.14 EGG02313.1 - 7e-21 74.0 0.0 8.6e-21 73.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF1883 PF08980.5 EGG02315.1 - 0.0043 16.5 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1883) BCMA-Tall_bind PF09257.5 EGG02315.1 - 0.13 12.1 1.5 0.18 11.7 0.2 1.9 1 1 1 2 2 2 0 BCMA, TALL-1 binding zf-CCHC PF00098.18 EGG02316.1 - 3.8e-16 58.1 21.3 2.5e-06 27.1 0.7 4.2 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EGG02316.1 - 0.0044 16.6 10.6 0.98 9.1 0.8 4.0 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.1 EGG02316.1 - 0.56 9.9 5.5 18 5.1 0.1 3.3 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.1 EGG02316.1 - 6.6 6.3 14.4 1.3 8.6 0.2 3.6 2 1 2 4 4 4 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGG02316.1 - 7.6 6.2 14.4 1.5 8.5 0.6 4.0 3 1 1 4 4 4 0 Zinc knuckle Biotin_lipoyl PF00364.17 EGG02317.1 - 1.6e-15 56.4 0.0 2.7e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EGG02317.1 - 3.5e-08 32.9 0.0 1.1e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EGG02317.1 - 0.00039 20.0 0.4 0.075 12.7 0.0 3.3 3 0 0 3 3 3 1 Biotin-lipoyl like zf-RING_2 PF13639.1 EGG02319.1 - 1.2e-05 24.9 10.6 2.6e-05 23.9 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGG02319.1 - 0.00033 20.2 7.4 0.00062 19.3 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG02319.1 - 0.00034 20.1 8.3 0.00077 19.0 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGG02319.1 - 0.005 16.3 3.5 0.005 16.3 2.4 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EGG02319.1 - 0.016 15.2 10.7 0.033 14.1 7.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG02319.1 - 0.03 14.0 8.4 0.087 12.5 5.8 1.8 1 1 0 1 1 1 0 zinc-RING finger domain CPSF_A PF03178.10 EGG02320.1 - 1e-96 323.8 0.0 4.1e-96 321.8 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EGG02320.1 - 3e-72 243.4 0.0 5e-72 242.6 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term M16C_assoc PF08367.6 EGG02320.1 - 0.13 11.1 0.1 0.25 10.1 0.1 1.4 1 0 0 1 1 1 0 Peptidase M16C associated RPA_C PF08784.6 EGG02321.1 - 1.4e-09 38.2 0.4 3.1e-09 37.1 0.1 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EGG02321.1 - 4.8e-06 26.3 0.2 1.1e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2476 PF10630.4 EGG02321.1 - 0.047 13.5 0.1 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2476) Tubulin PF00091.20 EGG02323.1 - 4.4e-71 239.1 0.0 5e-70 235.6 0.0 2.0 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGG02323.1 - 2.4e-45 153.6 0.5 3.9e-45 152.9 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGG02323.1 - 0.00022 20.7 0.0 0.00045 19.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EGG02323.1 - 0.0038 17.2 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 2 Misato Segment II tubulin-like domain CN_hydrolase PF00795.17 EGG02323.1 - 0.033 13.5 0.0 0.075 12.3 0.0 1.4 1 1 0 1 1 1 0 Carbon-nitrogen hydrolase p450 PF00067.17 EGG02324.1 - 1.3e-08 33.8 0.0 1.6e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Choline_transpo PF04515.7 EGG02325.1 - 5e-37 127.3 12.9 5e-37 127.3 9.0 2.5 2 1 0 2 2 2 1 Plasma-membrane choline transporter Macoilin PF09726.4 EGG02326.1 - 0.26 9.5 3.3 0.34 9.1 2.3 1.1 1 0 0 1 1 1 0 Transmembrane protein API5 PF05918.6 EGG02326.1 - 2 6.8 4.9 2.2 6.6 3.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GSHPx PF00255.14 EGG02328.1 - 9.2e-39 131.1 0.2 1.2e-38 130.8 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 EGG02328.1 - 6.3e-07 29.0 0.0 9.5e-07 28.4 0.0 1.3 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGG02328.1 - 0.00056 19.5 0.0 0.00093 18.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF1573 PF07610.6 EGG02328.1 - 0.075 12.6 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) DNA_binding_1 PF01035.15 EGG02331.1 - 6e-22 77.1 0.0 5e-21 74.2 0.0 2.0 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Zn_clus PF00172.13 EGG02333.1 - 2e-05 24.3 9.3 4e-05 23.4 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup54 PF13874.1 EGG02333.1 - 0.074 12.7 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Dickkopf_N PF04706.7 EGG02333.1 - 0.59 10.3 7.9 1.2 9.3 5.5 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region G-alpha PF00503.15 EGG02336.1 - 9.1e-07 27.8 1.3 9.1e-07 27.8 0.9 1.6 1 1 1 2 2 2 1 G-protein alpha subunit DUF848 PF05852.6 EGG02337.1 - 0.031 14.1 0.3 0.068 13.0 0.2 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) CSD PF00313.17 EGG02338.1 - 6.4e-08 32.2 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain LSM PF01423.17 EGG02339.1 - 1.7e-18 65.9 0.3 1.9e-18 65.7 0.2 1.0 1 0 0 1 1 1 1 LSM domain Glyco_hydro_88 PF07470.8 EGG02340.1 - 1.6e-14 53.7 0.1 2.7e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 CPSase_L_D2 PF02786.12 EGG02344.1 - 0.94 8.7 2.3 1.9 7.7 1.6 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RNA_pol_Rpb5_C PF01191.14 EGG02346.1 - 1.1e-30 104.9 0.2 1.2e-30 104.8 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain TMA7 PF09072.5 EGG02347.1 - 5.2e-20 71.6 13.3 6.4e-20 71.3 9.2 1.1 1 0 0 1 1 1 1 Translation machinery associated TMA7 zf-UBR PF02207.15 EGG02348.1 - 7.9 6.2 11.8 7.6 6.3 1.6 2.4 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) ZZ PF00569.12 EGG02348.1 - 9.4 5.8 9.0 17 5.0 0.5 2.6 2 0 0 2 2 2 0 Zinc finger, ZZ type Cu-oxidase_3 PF07732.10 EGG02349.1 - 8.9e-43 144.7 7.5 2.3e-41 140.2 1.4 3.9 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG02349.1 - 9.2e-30 102.9 1.7 2.2e-20 72.5 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EGG02349.1 - 1.4e-21 77.0 0.4 9.3e-20 71.1 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase CactinC_cactus PF09732.4 EGG02350.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein AMP-binding PF00501.23 EGG02351.1 - 3.4e-63 213.4 0.0 4.7e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EGG02351.1 - 2.5e-20 72.5 0.5 4.4e-20 71.7 0.3 1.4 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EGG02351.1 - 1.2e-12 47.8 0.0 9e-05 22.6 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site YhjQ PF06564.7 EGG02351.1 - 0.0032 16.8 0.1 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 YhjQ protein Synaptobrevin PF00957.16 EGG02355.1 - 1.2e-28 98.5 3.2 1.2e-28 98.5 2.2 1.8 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 EGG02355.1 - 3.6e-24 84.1 0.2 7.8e-24 83.0 0.1 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain MFS_1 PF07690.11 EGG02356.1 - 8.5e-16 57.5 32.1 3e-15 55.7 20.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EGG02356.1 - 0.00011 21.9 0.6 0.00078 19.1 0.2 2.6 2 0 0 2 2 2 1 MFS_1 like family PLA2_B PF01735.13 EGG02357.1 - 4.1e-85 285.8 0.0 6.1e-85 285.2 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.17 EGG02357.1 - 0.001 19.0 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase NAD_binding_7 PF13241.1 EGG02359.1 - 1.9e-28 98.7 0.0 3.8e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EGG02359.1 - 1.4e-17 62.7 1.7 2.7e-17 61.8 1.2 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EGG02359.1 - 1.2e-10 40.1 0.3 2.1e-10 39.3 0.2 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 EGG02359.1 - 0.038 14.0 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EGG02359.1 - 0.066 13.3 0.2 0.5 10.4 0.0 2.2 1 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PAF-AH_p_II PF03403.8 EGG02360.1 - 1.6e-23 82.6 0.0 2.1e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EGG02360.1 - 2.4e-05 24.1 0.0 3.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGG02360.1 - 0.00044 20.0 0.0 0.00072 19.3 0.0 1.2 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EGG02360.1 - 0.012 15.5 0.1 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGG02360.1 - 0.014 14.3 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EGG02360.1 - 0.091 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase RNA12 PF10443.4 EGG02361.1 - 3.4e-95 319.0 0.0 1.8e-94 316.7 0.0 2.0 1 1 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EGG02361.1 - 3.8e-07 30.0 0.1 3e-06 27.0 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase RRM_1 PF00076.17 EGG02361.1 - 4e-05 23.1 0.0 9.3e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 EGG02361.1 - 0.0002 21.4 0.0 0.00072 19.5 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EGG02361.1 - 0.01 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGG02361.1 - 0.032 14.3 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.6 EGG02361.1 - 0.29 11.5 1.9 0.98 9.8 0.4 2.6 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF4534 PF15049.1 EGG02362.1 - 0.038 13.6 0.7 0.061 12.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) Hist_deacetyl PF00850.14 EGG02363.1 - 3.3e-75 253.2 0.1 4.2e-75 252.9 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain HEAT PF02985.17 EGG02364.1 - 1.2e-08 34.3 2.5 1.7 8.8 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 EGG02364.1 - 1.2e-06 28.6 1.0 0.0015 18.7 0.0 4.9 4 1 2 6 6 6 1 HEAT repeats CLASP_N PF12348.3 EGG02364.1 - 0.00068 19.0 0.0 0.054 12.8 0.0 3.2 3 1 0 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.1 EGG02364.1 - 0.0043 17.5 7.9 8.9 6.9 0.0 6.1 5 1 1 6 6 6 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EGG02364.1 - 0.017 15.0 1.6 0.057 13.3 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Elicitin PF00964.12 EGG02365.1 - 0.012 15.5 0.5 0.012 15.5 0.4 2.0 1 1 0 1 1 1 0 Elicitin zf-C2H2_4 PF13894.1 EGG02366.1 - 2.4e-11 43.0 7.5 1.7e-05 24.8 0.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGG02366.1 - 1.8e-08 34.2 9.2 1.6e-05 24.9 1.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 EGG02366.1 - 0.00026 21.0 5.3 0.00076 19.5 3.7 1.7 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EGG02366.1 - 0.00027 21.0 4.2 1.6 9.1 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-met2 PF12907.2 EGG02366.1 - 0.00061 19.7 1.9 0.00061 19.7 1.4 1.8 2 0 0 2 2 2 1 Zinc-binding GAGA PF09237.6 EGG02366.1 - 0.015 14.8 2.7 1.2 8.8 0.2 2.2 1 1 1 2 2 2 0 GAGA factor DUF629 PF04780.7 EGG02366.1 - 0.022 13.2 1.9 0.97 7.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 EGG02366.1 - 0.15 12.1 1.0 6.7 6.8 0.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EGG02366.1 - 0.99 9.4 3.5 1.4 8.8 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EGG02366.1 - 1.2 9.5 5.1 2.6 8.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EGG02366.1 - 2.6 8.3 5.1 21 5.4 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Snf7 PF03357.16 EGG02367.1 - 7.2e-24 84.0 13.1 8.8e-24 83.8 9.1 1.1 1 0 0 1 1 1 1 Snf7 DUF1743 PF08489.6 EGG02367.1 - 0.041 13.6 0.1 0.1 12.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1743) AAA_23 PF13476.1 EGG02367.1 - 2.4 8.4 5.4 3 8.1 3.7 1.1 1 0 0 1 1 1 0 AAA domain Cutinase PF01083.17 EGG02369.1 - 4.5e-29 101.4 0.7 5.7e-29 101.1 0.5 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 EGG02369.1 - 0.007 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 EGG02369.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain UPF0565 PF10561.4 EGG02369.1 - 0.026 13.4 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 PGAP1 PF07819.8 EGG02369.1 - 0.033 13.7 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.17 EGG02370.1 - 1.7e-24 86.5 0.5 2.4e-24 86.0 0.3 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 EGG02370.1 - 0.0042 16.9 0.0 0.0061 16.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 EGG02370.1 - 0.008 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain UPF0565 PF10561.4 EGG02370.1 - 0.021 13.6 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 PGAP1 PF07819.8 EGG02370.1 - 0.028 14.0 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 EGG02370.1 - 0.062 13.5 0.0 0.092 12.9 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.15 EGG02370.1 - 0.084 12.4 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGG02370.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.3 EGG02370.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) ICMT PF04140.9 EGG02371.1 - 8e-23 80.4 0.6 8e-23 80.4 0.4 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EGG02371.1 - 3.8e-14 52.6 1.4 3.8e-14 52.6 0.9 2.5 2 1 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.7 EGG02371.1 - 0.00012 21.5 4.1 0.00012 21.5 2.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EGG02371.1 - 0.96 9.2 19.3 0.013 15.2 6.9 2.2 1 1 1 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase DFP PF04127.10 EGG02372.1 - 2.2e-18 66.5 0.0 6.4e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein TruD PF01142.13 EGG02373.1 - 7.8e-62 209.1 0.0 4.2e-58 196.8 0.0 2.7 3 0 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) Cu-oxidase_2 PF07731.9 EGG02374.1 - 1.8e-37 127.9 2.2 1.7e-30 105.3 0.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGG02374.1 - 2e-35 121.0 10.7 2.4e-34 117.5 1.4 4.1 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EGG02374.1 - 5.2e-20 71.9 0.1 1e-17 64.4 0.0 3.2 3 0 0 3 3 3 1 Multicopper oxidase Pox_L3_FP4 PF03339.9 EGG02374.1 - 0.017 13.6 0.7 0.024 13.1 0.5 1.2 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein E1_DerP2_DerF2 PF02221.10 EGG02374.1 - 0.11 12.7 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 ML domain IDO PF01231.13 EGG02377.1 - 2.7e-108 362.1 0.0 3.2e-108 361.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase SET PF00856.23 EGG02378.1 - 1.7e-09 38.1 0.1 7.8e-09 36.0 0.1 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.7 EGG02378.1 - 0.042 14.2 0.1 0.96 9.8 0.0 2.4 2 0 0 2 2 2 0 SAF domain Alpha_kinase PF02816.13 EGG02380.1 - 9.9e-07 28.5 0.2 1.2e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 Alpha-kinase family SET PF00856.23 EGG02382.1 - 5e-07 30.1 0.1 1.9e-06 28.2 0.1 2.0 1 1 0 1 1 1 1 SET domain Phage_Mu_Gam PF07352.7 EGG02382.1 - 0.12 11.8 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein SET PF00856.23 EGG02383.1 - 8.1e-10 39.2 0.1 7.4e-09 36.1 0.1 2.6 2 1 0 2 2 2 1 SET domain SAF PF08666.7 EGG02383.1 - 0.12 12.7 0.0 2.2 8.7 0.0 2.3 2 0 0 2 2 2 0 SAF domain Sugar_tr PF00083.19 EGG02384.1 - 1.6e-71 241.2 20.8 5.2e-71 239.5 14.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG02384.1 - 2.6e-27 95.4 43.8 1e-26 93.5 16.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGG02384.1 - 0.069 13.1 5.0 0.093 12.7 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Phage_holin_2 PF04550.7 EGG02384.1 - 0.5 10.4 5.4 1.5 8.9 3.8 1.7 1 0 0 1 1 1 0 Phage holin family 2 U79_P34 PF03064.11 EGG02385.1 - 1.6 8.2 12.4 1.9 7.9 8.6 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 IDO PF01231.13 EGG02388.1 - 1.1e-103 346.9 0.0 1.4e-103 346.6 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Pkinase PF00069.20 EGG02389.1 - 4e-71 239.2 0.0 4.8e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG02389.1 - 1.5e-32 112.7 0.0 1.9e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG02389.1 - 3.8e-07 29.3 0.0 6.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGG02389.1 - 0.00026 20.7 0.0 0.00048 19.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGG02389.1 - 0.0014 17.7 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGG02389.1 - 0.048 12.9 0.0 0.087 12.1 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL JmjN PF02375.12 EGG02390.1 - 4.6e-15 54.8 0.3 6.9e-15 54.2 0.2 1.3 1 0 0 1 1 1 1 jmjN domain JmjC PF02373.17 EGG02391.1 - 8e-38 129.1 0.1 1.1e-37 128.7 0.1 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase DEAD PF00270.24 EGG02392.1 - 1.4e-44 151.5 0.0 2.3e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG02392.1 - 9.3e-28 95.9 0.0 3.7e-27 93.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG02392.1 - 8.5e-06 25.7 0.6 0.00012 21.9 0.0 2.5 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EGG02392.1 - 0.024 13.9 0.0 0.13 11.5 0.0 1.9 1 1 0 1 1 1 0 SecA DEAD-like domain CENP-B_dimeris PF09026.5 EGG02392.1 - 0.031 14.4 4.4 0.061 13.5 3.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EGG02392.1 - 7.2 6.1 11.4 15 5.0 7.9 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF382 PF04037.8 EGG02393.1 - 5e-60 200.9 1.3 9.3e-60 200.0 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EGG02393.1 - 1.5e-21 75.4 7.1 3.2e-21 74.4 4.9 1.6 1 0 0 1 1 1 1 PSP PLA2_B PF01735.13 EGG02394.1 - 2.4e-79 266.7 0.1 5.6e-79 265.5 0.0 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.17 EGG02394.1 - 0.00035 20.5 0.2 0.00085 19.3 0.2 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase PLA2_B PF01735.13 EGG02396.1 - 5.9e-88 295.1 0.1 8.9e-88 294.5 0.1 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.17 EGG02396.1 - 1.1e-05 25.4 0.2 3.3e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase DUF2670 PF10875.3 EGG02397.1 - 0.042 13.8 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) THEG PF14912.1 EGG02397.1 - 0.13 12.8 4.1 0.3 11.6 0.1 3.1 3 0 0 3 3 3 0 Testicular haploid expressed repeat Peptidase_A3 PF02160.10 EGG02401.1 - 1.4 8.4 6.1 0.37 10.3 1.8 1.7 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) Cutinase PF01083.17 EGG02403.1 - 1e-29 103.5 1.1 1.3e-29 103.1 0.8 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EGG02403.1 - 0.024 14.0 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.6 EGG02403.1 - 0.035 13.8 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF1749 PF08538.5 EGG02403.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) UPF0565 PF10561.4 EGG02403.1 - 0.24 10.2 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Cutinase PF01083.17 EGG02404.1 - 3.5e-27 95.2 0.4 4.3e-27 95.0 0.3 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 EGG02404.1 - 0.0016 18.2 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.2 EGG02404.1 - 0.013 15.3 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0565 PF10561.4 EGG02404.1 - 0.02 13.7 0.0 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Abhydrolase_1 PF00561.15 EGG02404.1 - 0.026 14.1 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.6 EGG02404.1 - 0.063 12.6 0.0 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 PE-PPE domain DUF726 PF05277.7 EGG02404.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PGAP1 PF07819.8 EGG02404.1 - 0.2 11.2 0.0 0.29 10.6 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein EMP24_GP25L PF01105.19 EGG02405.1 - 9.8e-49 165.5 0.3 1.1e-48 165.3 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MFS_1 PF07690.11 EGG02406.1 - 2.1e-35 122.0 29.9 2.1e-35 122.0 20.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2975 PF11188.3 EGG02406.1 - 0.19 11.4 0.1 0.19 11.4 0.1 4.2 2 1 0 4 4 4 0 Protein of unknown function (DUF2975) tRNA-synt_2d PF01409.15 EGG02407.1 - 3e-87 291.8 0.0 4.6e-87 291.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EGG02407.1 - 3.4e-05 23.4 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EGG02407.1 - 9.3e-05 21.3 0.4 0.0022 16.8 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) IF3_N PF05198.11 EGG02407.1 - 0.013 15.4 0.1 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Oxidored_q1 PF00361.15 EGG02408.1 - 2.4e-13 49.9 5.7 2.6e-13 49.8 4.0 1.0 1 0 0 1 1 1 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Dynactin PF12455.3 EGG02409.1 - 2.7e-21 75.6 0.2 2.7e-21 75.6 0.1 1.9 2 0 0 2 2 2 1 Dynein associated protein Prophage_tail PF06605.6 EGG02409.1 - 0.061 12.2 0.7 0.083 11.8 0.5 1.2 1 0 0 1 1 1 0 Prophage endopeptidase tail Mu-like_Pro PF10123.4 EGG02409.1 - 0.64 9.4 5.3 0.66 9.3 3.6 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein SH2_2 PF14633.1 EGG02409.1 - 0.66 9.0 3.5 3.6 6.5 2.0 2.0 1 1 1 2 2 2 0 SH2 domain DUF4284 PF14112.1 EGG02409.1 - 0.93 9.9 4.5 0.69 10.4 1.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4284) DUF2730 PF10805.3 EGG02409.1 - 2.9 7.6 11.5 19 5.0 3.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) APG6 PF04111.7 EGG02409.1 - 3.4 6.6 17.5 5.1 6.0 12.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 LPP20 PF02169.11 EGG02409.1 - 5.8 7.0 7.0 3.9 7.6 1.3 2.6 2 1 0 2 2 2 0 LPP20 lipoprotein DivIVA PF05103.8 EGG02409.1 - 7.3 6.6 12.3 4.4 7.3 6.6 2.0 1 1 0 1 1 1 0 DivIVA protein Methyltransf_23 PF13489.1 EGG02410.1 - 8e-08 32.1 0.0 9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EGG02410.1 - 1.9e-05 24.0 0.0 2.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_11 PF08241.7 EGG02410.1 - 0.023 15.1 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGG02410.1 - 0.058 13.8 0.0 0.085 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGG02410.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EGG02410.1 - 0.12 11.4 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF43 PF01861.11 EGG02410.1 - 0.16 10.9 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF43 Kelch_2 PF07646.10 EGG02411.1 - 0.12 12.1 1.1 16 5.4 0.0 2.4 2 0 0 2 2 2 0 Kelch motif HEAT_EZ PF13513.1 EGG02414.1 - 0.0078 16.6 4.1 12 6.5 0.0 5.5 5 2 1 6 6 6 2 HEAT-like repeat CDK5_activator PF03261.10 EGG02415.1 - 0.6 9.3 6.3 0.63 9.3 4.4 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TEX19 PF15553.1 EGG02415.1 - 0.64 9.8 5.5 0.78 9.5 3.8 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 VP4_2 PF08935.5 EGG02415.1 - 9.3 6.9 10.7 0.91 10.1 3.1 2.0 1 1 1 2 2 2 0 Viral protein VP4 subunit Glyco_hydro_10 PF00331.15 EGG02416.1 - 2.6e-60 204.1 0.0 2.9e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 EGG02416.1 - 0.0071 16.7 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like PARP_regulatory PF01358.13 EGG02416.1 - 0.079 11.5 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit Tim17 PF02466.14 EGG02423.1 - 0.00032 20.7 0.7 0.00077 19.5 0.5 1.7 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Peroxidase_2 PF01328.12 EGG02424.1 - 2.9e-13 49.1 1.1 1.6e-12 46.7 0.8 2.0 1 1 0 1 1 1 1 Peroxidase, family 2 p450 PF00067.17 EGG02425.1 - 3.1e-57 194.1 0.0 4.3e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Daxx PF03344.10 EGG02426.1 - 1.1 7.6 24.6 0.76 8.1 16.1 1.4 2 0 0 2 2 2 0 Daxx Family Oxidored_q3 PF00499.15 EGG02427.1 - 0.15 11.8 1.1 0.17 11.6 0.8 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Abhydrolase_6 PF12697.2 EGG02428.1 - 1.6e-15 57.6 0.0 1.9e-14 54.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG02428.1 - 1.3e-05 24.9 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EGG02428.1 - 5.2e-05 22.9 0.1 0.0013 18.3 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGG02428.1 - 6.7e-05 22.6 0.0 0.0007 19.3 0.0 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGG02428.1 - 0.0042 16.3 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2305 PF10230.4 EGG02428.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 EGG02428.1 - 0.033 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase UPF0227 PF05728.7 EGG02428.1 - 0.089 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Pkinase PF00069.20 EGG02429.1 - 2.5e-63 213.6 0.0 1.6e-41 142.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGG02429.1 - 6.7e-30 104.0 0.0 3.8e-23 81.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EGG02429.1 - 8.4e-13 48.3 0.0 1.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EGG02429.1 - 0.00046 19.2 0.1 0.0018 17.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGG02429.1 - 0.0018 18.0 0.0 0.021 14.5 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGG02429.1 - 0.039 12.8 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EGG02429.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2306 PF10067.4 EGG02430.1 - 7 6.8 16.7 2.6 8.2 2.7 3.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) FKBP_C PF00254.23 EGG02431.1 - 1.5e-18 66.6 0.0 1.8e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Lipase_GDSL_2 PF13472.1 EGG02432.1 - 7.4e-05 22.9 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ribosomal_L29e PF01779.12 EGG02434.1 - 2.8e-22 78.2 11.2 4.1e-22 77.7 7.8 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Fungal_trans PF04082.13 EGG02435.1 - 3.3e-05 22.8 0.0 5.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGG02435.1 - 6e-05 22.8 9.6 6e-05 22.8 6.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2370 PF10176.4 EGG02437.1 - 3.1e-68 229.5 0.0 5e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 EGG02437.1 - 0.0028 17.8 2.8 0.027 14.6 2.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF202) Chordopox_A13L PF05961.6 EGG02437.1 - 0.07 13.0 1.0 3.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein FACT-Spt16_Nlob PF14826.1 EGG02438.1 - 8.2e-28 96.9 0.3 1.9e-27 95.7 0.2 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EGG02438.1 - 2.5e-18 66.4 0.0 4.2e-17 62.4 0.0 2.1 1 1 0 2 2 2 1 Metallopeptidase family M24 NAM-associated PF14303.1 EGG02438.1 - 3.8 7.7 9.7 0.3 11.4 0.7 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain FACT-Spt16_Nlob PF14826.1 EGG02439.1 - 1.8e-18 66.6 0.0 2.1e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EGG02440.1 - 2.1e-11 43.8 0.0 5e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Rubi_NSP_C PF12601.3 EGG02440.1 - 0.07 13.0 0.0 26 4.7 0.0 3.1 3 0 0 3 3 3 0 Rubivirus non-structural protein Sulfate_transp PF00916.15 EGG02441.1 - 2.4e-54 184.2 7.4 3.7e-54 183.6 5.1 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGG02441.1 - 2.4e-25 87.9 0.9 1.5e-24 85.4 0.8 2.4 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGG02441.1 - 3.6e-19 68.3 0.0 6.2e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EGG02441.1 - 0.00026 20.9 0.1 0.00064 19.7 0.0 1.7 1 0 0 1 1 1 1 STAS domain zf-RING_5 PF14634.1 EGG02442.1 - 5e-08 32.5 8.5 7.8e-08 31.9 5.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGG02442.1 - 0.00097 18.9 6.6 0.00097 18.9 4.6 1.8 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGG02442.1 - 0.0024 17.8 8.5 0.0044 17.0 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3039 PF11238.3 EGG02442.1 - 0.049 13.0 0.8 0.15 11.5 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) zf-C3HC4 PF00097.20 EGG02442.1 - 0.088 12.4 8.7 0.16 11.6 6.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HlyD PF00529.15 EGG02442.1 - 0.16 11.2 4.5 0.22 10.7 3.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Ribosomal_S27e PF01667.12 EGG02442.1 - 0.19 11.2 2.8 0.4 10.2 2.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 Zn-ribbon_8 PF09723.5 EGG02442.1 - 0.25 11.3 2.8 0.78 9.7 2.0 1.9 1 0 0 1 1 1 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EGG02442.1 - 0.36 10.0 6.2 0.1 11.8 0.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain DUF1272 PF06906.6 EGG02442.1 - 0.43 10.4 5.8 1.1 9.1 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 EGG02442.1 - 0.48 10.3 11.7 0.089 12.6 4.2 2.5 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING DZR PF12773.2 EGG02442.1 - 0.55 10.1 4.6 1.6 8.5 3.2 1.8 1 1 0 1 1 1 0 Double zinc ribbon Cse1 PF08506.5 EGG02443.1 - 8.9e-138 458.8 3.3 1.3e-137 458.3 2.3 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 EGG02443.1 - 1.7e-111 372.6 1.1 1.7e-111 372.6 0.8 1.8 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EGG02443.1 - 1.1e-12 47.6 1.3 1.1e-12 47.6 0.9 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EGG02443.1 - 0.36 10.7 6.2 1.8 8.4 0.5 4.2 3 2 1 4 4 4 0 Exportin 1-like protein zf-3CxxC PF13695.1 EGG02444.1 - 2.3 8.4 10.1 0.8 9.9 1.0 3.4 3 0 0 3 3 3 0 Zinc-binding domain IDH PF03971.9 EGG02447.1 - 0.02 13.2 0.0 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase DUF1769 PF08588.5 EGG02451.1 - 0.00049 19.9 0.0 0.00059 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Nop14 PF04147.7 EGG02452.1 - 0.0057 14.6 7.9 0.0059 14.6 5.4 1.1 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.8 EGG02452.1 - 0.28 10.7 10.4 0.48 9.9 7.2 1.4 1 0 0 1 1 1 0 YL1 nuclear protein YqfQ PF14181.1 EGG02452.1 - 0.72 9.8 6.3 1.2 9.1 4.4 1.3 1 0 0 1 1 1 0 YqfQ-like protein Pox_RNA_Pol_19 PF05320.7 EGG02452.1 - 1.3 8.7 6.5 1.8 8.3 4.5 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Hid1 PF12722.2 EGG02452.1 - 1.6 6.2 6.0 2 5.9 4.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NOA36 PF06524.7 EGG02452.1 - 1.6 7.8 8.7 2.3 7.4 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 EGG02452.1 - 4.4 6.3 13.2 5.7 5.9 9.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-B_dimeris PF09026.5 EGG02452.1 - 5.9 7.2 14.3 9.5 6.5 9.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 EGG02452.1 - 8.9 4.2 12.9 11 3.9 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein UNC-93 PF05978.11 EGG02453.1 - 6.9e-15 54.8 6.0 2.2e-14 53.2 4.2 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EGG02453.1 - 1.5e-12 46.9 28.9 1.5e-12 46.9 20.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF966 PF06136.8 EGG02454.1 - 1.4 8.2 12.2 1.8 7.8 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RAP1 PF07218.6 EGG02454.1 - 5.9 4.8 9.2 7.4 4.5 6.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1770 PF08589.5 EGG02455.1 - 0.011 16.3 0.7 0.011 16.3 0.5 2.9 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF1770) DUF1168 PF06658.7 EGG02456.1 - 0.023 14.2 12.9 0.024 14.1 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) bZIP_Maf PF03131.12 EGG02456.1 - 0.68 10.2 5.8 0.78 10.0 4.0 1.1 1 0 0 1 1 1 0 bZIP Maf transcription factor Selenoprotein_S PF06936.6 EGG02456.1 - 0.96 8.9 6.3 1 8.8 4.4 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) Vfa1 PF08432.5 EGG02456.1 - 9.3 6.2 9.4 9.6 6.1 6.5 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Skp1 PF01466.14 EGG02457.1 - 7.1e-38 128.5 0.7 1.1e-37 127.8 0.5 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EGG02457.1 - 6.8e-26 90.1 0.6 1.4e-25 89.1 0.4 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 EGG02457.1 - 0.00071 19.5 0.0 0.0093 15.9 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain DUF4375 PF14300.1 EGG02457.1 - 0.015 15.2 0.3 0.48 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) DUF4218 PF13960.1 EGG02458.1 - 9.5e-06 25.0 0.7 1.4e-05 24.5 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Rib_5-P_isom_A PF06026.9 EGG02460.1 - 1.6e-55 187.0 0.0 2.2e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) OppC_N PF12911.2 EGG02461.1 - 0.12 11.7 3.2 0.65 9.4 0.0 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C RIC3 PF15361.1 EGG02461.1 - 0.42 10.8 2.3 0.55 10.4 1.6 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Myosin_head PF00063.16 EGG02462.1 - 1.3e-241 803.4 7.9 1.7e-241 803.1 0.0 2.3 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EGG02462.1 - 3.6e-34 116.7 3.1 3.6e-34 116.7 2.1 2.4 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 EGG02462.1 - 6.5e-07 28.4 24.0 0.02 14.4 0.1 5.9 5 0 0 5 5 5 3 IQ calmodulin-binding motif AAA_22 PF13401.1 EGG02462.1 - 0.0011 19.1 0.1 0.022 14.9 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGG02462.1 - 0.071 12.8 0.0 0.3 10.8 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain NAD_binding_4 PF07993.7 EGG02464.1 - 6.8e-24 84.1 0.0 8.8e-24 83.7 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGG02464.1 - 9.8e-14 51.3 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EGG02464.1 - 0.014 15.0 0.0 0.03 13.9 0.0 1.5 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 EGG02464.1 - 0.039 12.8 0.1 0.57 9.0 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGG02464.1 - 0.098 11.5 0.0 3.6 6.3 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 EGG02464.1 - 0.39 10.6 1.4 1.4 8.8 1.0 1.9 1 1 0 1 1 1 0 short chain dehydrogenase dsDNA_bind PF01984.15 EGG02465.1 - 3.3e-24 84.9 3.2 4.5e-24 84.4 2.2 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain ELL PF10390.4 EGG02465.1 - 0.071 12.3 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL DUF1376 PF07120.6 EGG02465.1 - 0.13 12.4 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) CsbD PF05532.7 EGG02466.1 - 0.012 15.2 1.9 0.018 14.7 1.3 1.2 1 0 0 1 1 1 0 CsbD-like AAA_11 PF13086.1 EGG02467.1 - 3.7e-56 190.3 0.1 6.1e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EGG02467.1 - 8e-55 185.3 0.0 1.3e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGG02467.1 - 2.5e-16 59.1 1.5 9.4e-15 54.1 0.7 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EGG02467.1 - 4.2e-14 52.5 0.0 6e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EGG02467.1 - 2.5e-08 33.7 0.0 0.076 12.5 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EGG02467.1 - 1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EGG02467.1 - 5.1e-05 22.6 0.0 0.054 12.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.16 EGG02467.1 - 0.00012 21.5 0.0 0.00039 19.8 0.0 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EGG02467.1 - 0.00048 20.2 0.0 0.0019 18.2 0.0 2.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.24 EGG02467.1 - 0.00079 19.6 0.2 0.037 14.2 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EGG02467.1 - 0.0017 17.4 0.1 0.12 11.3 0.1 2.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 EGG02467.1 - 0.0019 17.6 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 EGG02467.1 - 0.0022 16.9 0.0 0.0042 16.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PIF1 PF05970.9 EGG02467.1 - 0.0023 16.9 0.0 0.13 11.1 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase AAA_22 PF13401.1 EGG02467.1 - 0.0028 17.7 0.1 0.024 14.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGG02467.1 - 0.0032 16.9 0.0 0.0083 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain Zot PF05707.7 EGG02467.1 - 0.0071 15.8 0.0 0.021 14.3 0.0 1.8 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.1 EGG02467.1 - 0.008 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.9 EGG02467.1 - 0.0085 15.7 0.2 0.075 12.6 0.1 2.4 1 1 0 1 1 1 1 Helicase AAA_25 PF13481.1 EGG02467.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 EGG02467.1 - 0.011 14.3 0.0 0.02 13.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 EGG02467.1 - 0.037 13.7 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase SRP54 PF00448.17 EGG02467.1 - 0.051 13.0 0.1 0.89 8.9 0.0 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.12 EGG02467.1 - 0.067 12.6 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein UvrD_C PF13361.1 EGG02467.1 - 0.085 12.3 0.2 0.51 9.7 0.1 2.1 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain NEAT PF05031.7 EGG02467.1 - 0.098 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Iron Transport-associated domain PP2C PF00481.16 EGG02468.1 - 2.5e-06 27.0 0.0 3.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Catalase PF00199.14 EGG02473.1 - 1.1e-132 442.3 0.1 1.3e-132 442.1 0.1 1.0 1 0 0 1 1 1 1 Catalase Lipase_3 PF01764.20 EGG02476.1 - 2.8e-08 33.4 1.2 3.4e-08 33.2 0.2 1.6 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.3 EGG02476.1 - 0.013 14.9 0.2 0.021 14.1 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) HTH_21 PF13276.1 EGG02477.1 - 1.9e-05 24.5 2.9 0.0046 16.9 0.3 2.4 2 0 0 2 2 2 2 HTH-like domain HTH_32 PF13565.1 EGG02477.1 - 0.0016 19.2 3.2 3.1 8.6 0.0 3.3 2 1 0 2 2 2 2 Homeodomain-like domain Arg_repressor PF01316.16 EGG02477.1 - 0.032 13.7 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Clr5 PF14420.1 EGG02477.1 - 0.041 13.7 0.0 0.63 9.9 0.0 2.4 2 0 0 2 2 2 0 Clr5 domain DUF2420 PF10336.4 EGG02477.1 - 0.059 12.9 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) HTH_33 PF13592.1 EGG02477.1 - 0.13 11.8 1.5 22 4.6 0.0 3.4 3 0 0 3 3 3 0 Winged helix-turn helix PspA_IM30 PF04012.7 EGG02479.1 - 0.018 14.4 1.3 0.034 13.4 0.9 1.5 1 0 0 1 1 1 0 PspA/IM30 family Ufd2P_core PF10408.4 EGG02482.1 - 2.2e-11 42.7 0.1 2.7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core BSP_II PF05432.6 EGG02489.1 - 0.02 14.1 1.6 0.059 12.6 0.4 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TFIIE-A_C-term PF11521.3 EGG02489.1 - 1.3 9.0 6.7 0.41 10.6 0.2 2.1 1 1 1 2 2 2 0 C-terminal general transcription factor TFIIE alpha ABC_membrane PF00664.18 EGG02490.1 - 4.2e-13 49.3 3.9 5.4e-13 48.9 2.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGG02490.1 - 2.1e-12 47.5 0.1 3.3e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 ABC transporter Patched PF02460.13 EGG02490.1 - 0.018 13.0 0.2 0.067 11.1 0.2 1.7 2 0 0 2 2 2 0 Patched family Methyltransf_4 PF02390.12 EGG02492.1 - 0.018 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase TACC PF05010.9 EGG02495.1 - 0.019 14.7 1.3 0.046 13.4 0.4 1.9 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) DUF2205 PF10224.4 EGG02495.1 - 0.033 13.7 0.1 0.084 12.4 0.1 1.6 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) FlaC_arch PF05377.6 EGG02495.1 - 0.11 12.3 0.8 0.31 10.9 0.6 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PAT1 PF09770.4 EGG02495.1 - 6.8 4.8 16.9 10 4.1 11.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SURF4 PF02077.10 EGG02496.1 - 1.9e-90 302.9 4.4 2.2e-90 302.6 3.0 1.0 1 0 0 1 1 1 1 SURF4 family AhpC-TSA_2 PF13911.1 EGG02499.1 - 4.7e-12 45.8 0.0 9.8e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGG02499.1 - 0.00014 21.5 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Glyoxal_oxid_N PF07250.6 EGG02500.1 - 7e-46 156.2 0.4 5.2e-44 150.1 0.1 3.2 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EGG02500.1 - 1.7e-21 76.1 0.3 3.3e-21 75.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EGG02500.1 - 9e-05 22.1 1.2 0.28 10.9 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain DUF2611 PF11022.3 EGG02501.1 - 1.1e-19 70.2 0.1 1.2e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) COesterase PF00135.23 EGG02502.1 - 1.8e-78 264.5 0.0 8.5e-53 179.8 0.0 2.4 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGG02502.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PolyA_pol PF01743.15 EGG02503.1 - 9.5e-28 96.9 0.4 1.4e-27 96.4 0.0 1.4 2 0 0 2 2 2 1 Poly A polymerase head domain Vps52 PF04129.7 EGG02504.1 - 1.5e-47 162.2 11.1 7.1e-31 107.3 0.3 3.5 4 0 0 4 4 4 3 Vps52 / Sac2 family GP41 PF00517.12 EGG02504.1 - 0.098 12.2 0.1 0.098 12.2 0.1 2.3 2 0 0 2 2 2 0 Retroviral envelope protein RNA_pol_Rpb1_5 PF04998.12 EGG02504.1 - 9.7 5.3 9.1 0.26 10.4 0.3 2.5 3 1 1 4 4 4 0 RNA polymerase Rpb1, domain 5 L51_S25_CI-B8 PF05047.11 EGG02508.1 - 1.5e-10 40.6 0.1 2.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ThiF PF00899.16 EGG02509.1 - 1.1e-09 38.2 0.0 2.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 ThiF family zf-BED PF02892.10 EGG02510.1 - 0.0011 18.7 0.0 0.0063 16.2 0.0 2.4 2 0 0 2 2 2 1 BED zinc finger TFIIA PF03153.8 EGG02510.1 - 5.9 6.6 15.9 9.8 5.9 11.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MerE PF05052.7 EGG02511.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 MerE protein EMG1 PF03587.9 EGG02514.1 - 4.3e-75 251.4 0.3 5e-75 251.2 0.2 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase MOR2-PAG1_N PF14222.1 EGG02515.1 - 2.4e-109 366.5 0.0 4.2e-109 365.7 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EGG02515.1 - 1.1e-47 162.9 0.1 2.4e-47 161.8 0.1 1.5 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EGG02515.1 - 2.6e-09 35.2 2.3 4.2e-07 27.9 0.3 3.0 3 0 0 3 3 3 2 Cell morphogenesis central region Anophelin PF10731.4 EGG02515.1 - 2.3 8.3 0.0 2.3 8.3 0.0 4.0 4 0 0 4 4 4 0 Thrombin inhibitor from mosquito Daxx PF03344.10 EGG02515.1 - 4.1 5.7 19.3 8.6 4.7 13.4 1.4 1 0 0 1 1 1 0 Daxx Family zf-RING_6 PF14835.1 EGG02516.1 - 0.13 12.0 2.0 0.24 11.2 1.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RecR PF02132.10 EGG02516.1 - 0.73 9.3 7.7 0.49 9.8 3.4 1.9 2 0 0 2 2 2 0 RecR protein RRN7 PF11781.3 EGG02516.1 - 1.5 8.4 6.5 3.5 7.1 0.4 2.4 1 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-NADH-PPase PF09297.6 EGG02516.1 - 5.2 6.6 6.3 3.4 7.2 0.7 2.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain COesterase PF00135.23 EGG02518.1 - 1.5e-92 311.1 0.0 2.3e-92 310.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGG02518.1 - 8.8e-06 25.4 0.4 0.0096 15.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGG02518.1 - 0.0055 15.9 0.2 0.0093 15.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2533 PF10752.4 EGG02520.1 - 0.017 15.3 1.4 0.054 13.8 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) YfhO PF09586.5 EGG02521.1 - 0.095 10.7 1.1 0.15 10.0 0.7 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO UPF0227 PF05728.7 EGG02525.1 - 0.11 12.1 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Plus-3 PF03126.13 EGG02527.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Plus-3 domain Toxin_51 PF15531.1 EGG02527.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 51 Nic96 PF04097.9 EGG02530.1 - 1.9e-171 571.3 1.0 2.5e-171 570.9 0.7 1.1 1 0 0 1 1 1 1 Nup93/Nic96 DUF3713 PF12506.3 EGG02532.1 - 0.083 12.9 0.1 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) Npa1 PF11707.3 EGG02533.1 - 1.8e-25 89.6 0.4 1.7e-24 86.4 0.3 2.6 1 1 0 1 1 1 1 Ribosome 60S biogenesis N-terminal DUF1804 PF08822.6 EGG02533.1 - 0.38 10.4 1.8 5.4 6.7 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1804) Desmo_N PF06771.6 EGG02533.1 - 4.6 7.2 7.2 3.7 7.5 0.0 4.6 5 0 0 5 5 5 0 Viral Desmoplakin N-terminus zf-met PF12874.2 EGG02534.1 - 2.2e-05 24.5 1.9 4.1e-05 23.6 1.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGG02534.1 - 4.8e-05 23.3 0.8 8.5e-05 22.5 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGG02534.1 - 0.022 14.8 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EGG02534.1 - 0.066 13.5 2.1 0.13 12.6 1.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2284 PF10050.4 EGG02534.1 - 0.83 9.2 4.3 1.3 8.5 0.5 2.6 2 1 1 3 3 3 0 Predicted metal-binding protein (DUF2284) Atg14 PF10186.4 EGG02534.1 - 1.8 7.4 17.6 0.49 9.2 4.8 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Snf7 PF03357.16 EGG02534.1 - 2.9 7.2 21.9 1.7 8.0 0.1 3.1 3 0 0 3 3 3 0 Snf7 Peptidase_S64 PF08192.6 EGG02534.1 - 6.3 4.9 9.5 7.8 4.6 6.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4660 PF15559.1 EGG02534.1 - 7.6 6.6 10.5 0.19 11.8 2.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) DUF342 PF03961.8 EGG02534.1 - 8.9 4.5 13.4 0.74 8.1 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF4207 PF13904.1 EGG02535.1 - 0.023 14.0 0.0 0.023 14.0 0.0 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4207) Kei1 PF08552.6 EGG02536.1 - 6.5e-39 133.5 2.6 1.1e-38 132.8 1.8 1.4 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 AhpC-TSA_2 PF13911.1 EGG02538.1 - 5e-10 39.3 0.0 9.8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGG02538.1 - 0.00087 18.9 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family ThiF PF00899.16 EGG02539.1 - 6.9e-39 132.7 0.2 2.4e-38 131.0 0.0 1.9 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EGG02539.1 - 4.2e-27 93.5 3.4 6.9e-27 92.8 0.7 2.4 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGG02539.1 - 3.8e-22 77.3 2.1 3.8e-22 77.3 1.5 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EGG02539.1 - 0.00021 21.4 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EGG02539.1 - 0.00045 20.4 0.1 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Saccharop_dh PF03435.13 EGG02539.1 - 0.0015 17.6 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pyr_redox PF00070.22 EGG02539.1 - 0.066 13.6 0.0 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RNA_pol_Rpb2_6 PF00562.23 EGG02540.1 - 2.1e-109 365.8 0.0 2.8e-109 365.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGG02540.1 - 1.9e-34 118.3 0.0 3e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EGG02540.1 - 9.5e-24 82.9 0.0 1.9e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EGG02540.1 - 2.3e-20 72.8 0.0 3.5e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 EGG02540.1 - 1.1e-19 70.1 0.0 2.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EGG02540.1 - 2.4e-18 66.1 0.0 1.5e-17 63.6 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EGG02540.1 - 5.9e-06 26.1 0.0 1.8e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Cation_ATPase_C PF00689.16 EGG02541.1 - 0.041 13.4 0.0 0.095 12.2 0.0 1.7 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus CAP59_mtransfer PF11735.3 EGG02542.1 - 1.7e-18 66.7 0.0 2.5e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 FAM124 PF15067.1 EGG02542.1 - 0.1 12.0 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FAM124 family DUF702 PF05142.7 EGG02543.1 - 0.02 15.0 4.5 0.04 14.0 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Mg_trans_NIPA PF05653.9 EGG02544.1 - 5.9e-110 366.9 13.6 7.7e-110 366.5 9.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EGG02544.1 - 6.2e-09 36.0 0.7 6.2e-09 36.0 0.5 3.5 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EGG02544.1 - 8.1e-06 25.8 4.2 8.1e-06 25.8 2.9 3.3 2 1 1 3 3 3 1 EamA-like transporter family Acyl_transf_3 PF01757.17 EGG02544.1 - 0.23 10.2 19.2 0.045 12.5 4.6 2.3 1 1 1 2 2 2 0 Acyltransferase family DUF202 PF02656.10 EGG02544.1 - 0.43 10.8 11.8 0.83 9.9 1.2 4.3 2 2 1 3 3 3 0 Domain of unknown function (DUF202) RseC_MucC PF04246.7 EGG02544.1 - 0.56 9.7 7.6 5.9 6.4 0.1 3.0 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC TPT PF03151.11 EGG02544.1 - 2.8 7.5 23.0 2 8.0 8.8 3.2 2 2 1 3 3 3 0 Triose-phosphate Transporter family Sigma70_ner PF04546.8 EGG02545.1 - 1.5 8.3 8.2 1.8 8.1 5.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.1 EGG02545.1 - 3.4 7.3 7.3 4.4 6.9 5.0 1.3 1 0 0 1 1 1 0 FAM176 family La PF05383.12 EGG02546.1 - 1e-18 66.8 0.1 1.8e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 La domain Oxidored-like PF09791.4 EGG02547.1 - 1.7e-15 56.1 2.2 3.4e-15 55.2 1.5 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal vATP-synt_E PF01991.13 EGG02548.1 - 1.6e-57 193.9 14.9 1.9e-57 193.7 10.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Vps35 PF03635.12 EGG02548.1 - 0.027 12.6 5.3 0.031 12.4 3.7 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 DUF1828 PF08861.5 EGG02548.1 - 0.038 13.6 2.8 2.9 7.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF1828 SCAN PF02023.12 EGG02548.1 - 0.039 13.4 1.0 0.093 12.2 0.5 1.9 1 1 0 1 1 1 0 SCAN domain DUF4144 PF13642.1 EGG02548.1 - 0.14 12.5 1.3 0.24 11.7 0.2 1.9 1 1 1 2 2 2 0 protein structure with unknown function Radial_spoke_3 PF06098.6 EGG02548.1 - 0.15 10.9 13.3 0.21 10.5 9.2 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 SurA_N PF09312.6 EGG02548.1 - 0.51 10.2 7.0 0.21 11.4 0.5 2.5 1 1 1 2 2 2 0 SurA N-terminal domain Phlebovirus_NSM PF07246.6 EGG02548.1 - 0.91 8.6 10.2 1.3 8.1 7.1 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M PRP1_N PF06424.7 EGG02548.1 - 1.3 9.3 8.1 1.4 9.2 4.8 1.6 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal UPF0449 PF15136.1 EGG02548.1 - 3.2 8.0 6.8 1.5 9.0 2.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Lipase_GDSL_2 PF13472.1 EGG02549.1 - 0.028 14.5 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ALG3 PF05208.8 EGG02550.1 - 3.8e-39 134.9 21.5 8.7e-16 58.1 0.9 3.1 1 1 2 3 3 3 3 ALG3 protein BPD_transp_1 PF00528.17 EGG02550.1 - 2.5 7.5 7.8 0.45 10.0 0.5 2.4 2 1 1 3 3 3 0 Binding-protein-dependent transport system inner membrane component DUF3395 PF11875.3 EGG02553.1 - 0.049 13.2 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) DUF4218 PF13960.1 EGG02555.1 - 3.3e-06 26.5 0.4 5.3e-06 25.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) STAT_alpha PF01017.15 EGG02556.1 - 0.16 11.6 4.1 0.059 13.0 0.4 1.8 2 0 0 2 2 2 0 STAT protein, all-alpha domain CDK5_activator PF03261.10 EGG02556.1 - 0.72 9.1 6.2 1.3 8.3 4.3 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4140 PF13600.1 EGG02556.1 - 1.8 9.0 5.6 20 5.6 0.2 2.8 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Ala_racemase_C PF00842.16 EGG02559.1 - 0.075 12.4 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain Methyltransf_5 PF01795.14 EGG02560.1 - 0.082 12.1 0.5 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 MraW methylase family DUF724 PF05266.9 EGG02560.1 - 0.083 12.4 0.3 0.11 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4218 PF13960.1 EGG02561.1 - 5.4e-07 29.0 2.3 1e-06 28.1 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DZF PF07528.9 EGG02563.1 - 0.043 13.2 0.1 0.055 12.8 0.1 1.1 1 0 0 1 1 1 0 DZF domain Seryl_tRNA_N PF02403.17 EGG02564.1 - 0.0013 18.6 2.4 0.0041 17.1 1.6 1.9 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain GAS PF13851.1 EGG02564.1 - 0.003 16.7 7.2 0.0061 15.7 5.0 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 EGG02564.1 - 0.029 14.1 1.5 0.029 14.1 1.0 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 EGG02564.1 - 0.055 13.7 6.9 0.11 12.7 0.8 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Not3 PF04065.10 EGG02564.1 - 0.076 12.2 8.0 0.54 9.4 5.6 2.2 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF4407 PF14362.1 EGG02564.1 - 1.2 7.9 5.6 14 4.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.2 EGG02564.1 - 2.1 8.1 16.4 0.57 10.0 2.0 2.9 2 1 1 3 3 3 0 Tropomyosin like Nup54 PF13874.1 EGG02564.1 - 2.3 7.8 7.0 0.81 9.3 2.4 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 IncA PF04156.9 EGG02564.1 - 9 5.8 9.3 22 4.5 6.4 1.7 1 0 0 1 1 1 0 IncA protein Mucin PF01456.12 EGG02566.1 - 0.97 9.2 8.4 2.1 8.1 5.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4559 PF15112.1 EGG02569.1 - 0.11 11.6 4.3 0.16 11.0 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) zf-RING_2 PF13639.1 EGG02571.1 - 1.6e-07 31.0 8.5 1.6e-07 31.0 5.9 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 EGG02571.1 - 0.012 15.4 5.0 0.024 14.4 3.5 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGG02571.1 - 0.02 14.6 8.8 0.066 12.9 6.1 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGG02571.1 - 0.078 12.6 9.1 0.38 10.4 6.5 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EGG02571.1 - 0.086 12.8 3.2 1.8 8.6 0.2 2.5 2 0 0 2 2 2 0 zinc-finger zf-Apc11 PF12861.2 EGG02571.1 - 0.16 11.8 4.7 0.88 9.4 3.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGG02571.1 - 0.18 11.9 6.0 0.37 10.9 4.2 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGG02571.1 - 0.21 11.6 6.8 0.48 10.5 4.8 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGG02571.1 - 0.22 11.1 5.5 0.58 9.7 3.7 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Endonuclease_7 PF02945.10 EGG02571.1 - 0.28 10.8 5.0 0.48 10.1 3.5 1.3 1 0 0 1 1 1 0 Recombination endonuclease VII zf-C3HC4 PF00097.20 EGG02571.1 - 0.47 10.1 6.9 0.92 9.2 4.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EGG02571.1 - 1.2 9.1 5.7 3.1 7.8 4.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-MIZ PF02891.15 EGG02571.1 - 4.9 6.7 7.8 49 3.5 3.8 2.5 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger Alpha_kinase PF02816.13 EGG02572.1 - 1.6e-10 40.9 0.0 4.7e-10 39.4 0.0 1.7 1 1 1 2 2 2 1 Alpha-kinase family Lipase_3 PF01764.20 EGG02573.1 - 4.3e-09 36.1 0.5 2.3e-08 33.7 0.4 2.0 1 1 0 1 1 1 1 Lipase (class 3) MADF_DNA_bdg PF10545.4 EGG02573.1 - 0.083 13.0 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Glyco_transf_90 PF05686.7 EGG02574.1 - 2.8e-18 65.8 0.6 6.7e-16 57.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 FXR1P_C PF12235.3 EGG02577.1 - 0.025 14.6 9.2 0.038 14.1 6.4 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal DUF3827 PF12877.2 EGG02577.1 - 2.1 6.3 17.0 2.2 6.2 11.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Pacs-1 PF10254.4 EGG02577.1 - 4.3 5.8 8.5 5.1 5.6 5.9 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein MAT1 PF06391.8 EGG02577.1 - 5.5 6.5 9.3 6.1 6.3 5.9 1.4 1 1 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Paramyxo_ncap PF00973.14 EGG02577.1 - 6.3 5.3 9.7 7.6 5.1 6.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ETRAMP PF09716.5 EGG02577.1 - 6.8 6.7 9.2 2.3 8.2 4.4 1.8 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Pex14_N PF04695.8 EGG02577.1 - 7.8 6.5 11.0 11 6.0 7.1 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4618 PF15397.1 EGG02578.1 - 0.018 14.4 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Baculo_PEP_C PF04513.7 EGG02578.1 - 0.031 14.1 0.1 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNA_primase_S PF01896.14 EGG02580.1 - 2.9e-16 59.5 0.0 3.3e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Peptidase_C78 PF07910.8 EGG02582.1 - 2.3e-44 151.1 0.0 5.2e-34 117.2 0.0 2.5 1 1 1 2 2 2 2 Peptidase family C78 PGK PF00162.14 EGG02583.1 - 8.4e-150 498.6 1.7 9.4e-150 498.4 1.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase adh_short PF00106.20 EGG02584.1 - 1.3e-16 60.9 0.3 2.5e-16 60.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG02584.1 - 5.6e-15 55.7 0.0 6.6e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG02584.1 - 1.6e-08 34.3 0.1 2.7e-08 33.7 0.1 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGG02584.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) UPRTase PF14681.1 EGG02585.1 - 5.6e-60 202.0 0.0 6.3e-60 201.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EGG02585.1 - 0.00059 19.5 0.0 0.00084 19.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SlyX PF04102.7 EGG02587.1 - 0.11 12.9 6.9 0.074 13.4 2.8 2.2 1 1 1 2 2 2 0 SlyX Stm1_N PF09598.5 EGG02587.1 - 0.17 12.6 2.3 23 5.7 0.0 2.8 2 0 0 2 2 2 0 Stm1 FlaC_arch PF05377.6 EGG02587.1 - 0.2 11.5 6.2 0.66 9.9 1.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Bap31 PF05529.7 EGG02587.1 - 1.1 8.6 5.9 0.51 9.7 2.1 1.9 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Prefoldin_2 PF01920.15 EGG02587.1 - 4.9 6.9 16.8 1.1 9.1 2.4 3.1 2 1 0 3 3 3 0 Prefoldin subunit FliJ PF02050.11 EGG02588.1 - 0.085 12.9 5.5 0.16 12.0 3.8 1.6 1 1 0 1 1 1 0 Flagellar FliJ protein Sigma70_ner PF04546.8 EGG02589.1 - 0.013 15.1 2.1 0.016 14.8 0.3 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Mem_trans PF03547.13 EGG02591.1 - 0.16 10.2 0.1 0.15 10.3 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein COesterase PF00135.23 EGG02595.1 - 0.053 12.2 0.2 0.058 12.0 0.1 1.0 1 0 0 1 1 1 0 Carboxylesterase family Lipase_GDSL PF00657.17 EGG02596.1 - 2.1e-08 34.3 0.4 1.3e-07 31.6 0.1 2.0 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase Hexapep PF00132.19 EGG02597.1 - 7.3e-11 41.0 12.4 6.1e-06 25.5 2.9 4.1 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) W2 PF02020.13 EGG02597.1 - 2.4e-09 37.0 0.4 5.8e-09 35.7 0.3 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Fucokinase PF07959.7 EGG02597.1 - 0.046 12.2 1.5 0.083 11.4 1.1 1.3 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.1 EGG02597.1 - 0.67 9.5 15.1 1.8 8.1 2.1 4.0 2 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase CfAFP PF05264.6 EGG02597.1 - 9 6.0 10.6 0.51 10.1 2.6 2.4 2 1 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Apc1 PF12859.2 EGG02598.1 - 2e-10 40.7 0.0 2e-10 40.7 0.0 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EGG02598.1 - 0.34 11.2 14.8 0.21 11.9 0.1 5.3 6 0 0 6 6 6 0 Proteasome/cyclosome repeat p450 PF00067.17 EGG02601.1 - 1.6e-58 198.3 0.0 2.1e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SHMT PF00464.14 EGG02602.1 - 1.8e-06 26.5 0.0 2e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase GFA PF04828.9 EGG02603.1 - 1.3e-09 37.8 5.3 9.3e-09 35.1 1.7 3.2 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Sgf11 PF08209.6 EGG02603.1 - 0.44 9.8 7.1 2.4 7.5 2.4 3.0 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Cys_rich_CWC PF14375.1 EGG02603.1 - 7.4 6.5 10.3 0.54 10.2 3.1 2.1 2 1 0 2 2 2 0 Cysteine-rich CWC GFA PF04828.9 EGG02604.1 - 9.3e-11 41.5 0.6 4.1e-10 39.4 0.4 2.2 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RIG-I_C-RD PF11648.3 EGG02604.1 - 0.051 13.4 1.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I Sgf11 PF08209.6 EGG02604.1 - 0.34 10.2 6.3 0.94 8.8 1.4 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_4 PF13717.1 EGG02604.1 - 0.9 9.2 0.1 0.9 9.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGG02604.1 - 8.9 5.9 7.1 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-HIT PF04438.11 EGG02605.1 - 5.4e-08 32.3 11.2 8.4e-08 31.7 7.8 1.3 1 0 0 1 1 1 1 HIT zinc finger ArfGap PF01412.13 EGG02605.1 - 0.1 12.3 6.2 0.11 12.3 4.3 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf TYW3 PF02676.9 EGG02605.1 - 0.14 11.3 0.9 0.14 11.2 0.6 1.0 1 0 0 1 1 1 0 Methyltransferase TYW3 zf-UBP PF02148.14 EGG02605.1 - 0.27 11.3 7.7 0.3 11.2 5.3 1.3 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein PolC_DP2 PF03833.8 EGG02605.1 - 0.37 8.3 5.1 0.36 8.4 3.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Dicty_CTDC PF00526.13 EGG02605.1 - 0.47 10.3 9.5 2.6 7.9 1.5 2.9 3 1 0 3 3 3 0 Dictyostelium (slime mold) repeat zf-B_box PF00643.19 EGG02605.1 - 3.2 7.7 12.6 4.5 7.2 8.8 1.4 1 1 0 1 1 1 0 B-box zinc finger adh_short PF00106.20 EGG02611.1 - 2.7e-16 59.9 0.0 4.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG02611.1 - 9.1e-06 25.4 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGG02611.1 - 1.2e-05 25.1 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pyr_redox_3 PF13738.1 EGG02611.1 - 0.0058 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 EGG02611.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EGG02611.1 - 0.086 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGG02611.1 - 0.12 12.1 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADC PF06314.6 EGG02612.1 - 0.0051 16.1 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Snf7 PF03357.16 EGG02614.1 - 3.9e-19 68.6 21.2 7.4e-19 67.7 14.7 1.5 1 1 0 1 1 1 1 Snf7 RB_A PF01858.12 EGG02614.1 - 0.063 12.9 6.3 1.4 8.5 0.0 2.8 2 1 1 3 3 3 0 Retinoblastoma-associated protein A domain DUF948 PF06103.6 EGG02614.1 - 1.1 9.1 7.9 1.4 8.8 0.8 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.6 EGG02614.1 - 1.9 8.9 16.3 1.8 9.0 1.6 4.0 4 1 0 4 4 4 0 Syntaxin 6, N-terminal SGL PF08450.7 EGG02615.1 - 2.3e-06 27.1 0.0 4.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EGG02615.1 - 0.0004 20.3 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EGG02615.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 Arylesterase Fungal_trans PF04082.13 EGG02616.1 - 4.1e-40 137.2 3.2 4.1e-40 137.2 2.2 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EGG02616.1 - 0.0012 19.0 0.6 0.0012 19.0 0.4 4.8 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG02616.1 - 0.0018 18.5 2.5 0.0018 18.5 1.7 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGG02616.1 - 0.0075 16.5 0.7 0.0075 16.5 0.5 4.4 5 0 0 5 5 5 1 C2H2-type zinc finger Zn_clus PF00172.13 EGG02619.1 - 2.4e-06 27.3 6.0 5.4e-06 26.2 4.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pap_E4 PF02711.9 EGG02619.1 - 6.8 7.5 13.2 1.2 10.0 5.0 2.5 3 0 0 3 3 3 0 E4 protein CFEM PF05730.6 EGG02620.1 - 1.6e-12 47.0 5.2 3.2e-12 46.0 3.6 1.5 1 0 0 1 1 1 1 CFEM domain DUF605 PF04652.11 EGG02620.1 - 6.5 6.0 26.2 8.5 5.6 18.2 1.1 1 0 0 1 1 1 0 Vta1 like NAM-associated PF14303.1 EGG02621.1 - 5.6e-20 72.2 3.4 5.6e-20 72.2 2.4 2.0 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain YrbL-PhoP_reg PF10707.4 EGG02621.1 - 0.19 11.0 1.7 1.6 7.9 0.0 2.1 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL CLP_protease PF00574.18 EGG02621.1 - 0.34 10.5 2.4 0.33 10.5 0.7 1.6 1 1 1 2 2 2 0 Clp protease CPSF73-100_C PF11718.3 EGG02623.1 - 5.8e-47 159.8 0.1 9.1e-47 159.1 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EGG02623.1 - 8.6e-29 100.0 0.0 1.8e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EGG02623.1 - 5.5e-13 48.9 0.1 1.9e-12 47.2 0.1 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGG02623.1 - 2.5e-11 43.5 0.0 6.7e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EGG02623.1 - 3.1e-09 36.4 0.0 6.3e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EGG02623.1 - 1.1e-06 28.4 0.3 9.1e-06 25.4 0.1 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain TPT PF03151.11 EGG02624.1 - 5.3e-15 55.3 15.4 5.3e-15 55.3 10.7 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EGG02624.1 - 0.0017 17.3 23.3 0.074 11.9 16.1 2.4 1 1 0 1 1 1 1 UAA transporter family Gemini_mov PF01708.11 EGG02624.1 - 0.15 11.5 1.2 23 4.6 0.6 3.1 2 0 0 2 2 2 0 Geminivirus putative movement protein FAM60A PF15396.1 EGG02624.1 - 6.4 6.4 6.8 36 4.0 4.7 1.9 1 1 0 1 1 1 0 Protein Family FAM60A DivIC PF04977.10 EGG02625.1 - 0.0031 16.9 21.0 0.0041 16.5 3.1 3.9 1 1 3 4 4 4 2 Septum formation initiator DUF4200 PF13863.1 EGG02625.1 - 0.098 12.6 25.9 1.7 8.5 4.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 EGG02625.1 - 0.11 12.2 31.6 0.045 13.5 10.8 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein M3 PF09213.5 EGG02625.1 - 0.12 10.7 0.2 0.2 10.0 0.1 1.3 1 0 0 1 1 1 0 M3 CENP-F_leu_zip PF10473.4 EGG02625.1 - 0.23 11.3 28.6 0.25 11.2 2.2 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EGG02625.1 - 0.85 9.1 36.5 0.21 11.1 4.8 2.5 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 EGG02625.1 - 1 8.5 33.2 0.85 8.7 2.3 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding RBD-FIP PF09457.5 EGG02625.1 - 1.8 8.4 8.7 0.95 9.3 0.3 2.9 2 0 0 2 2 2 0 FIP domain Tup_N PF08581.5 EGG02625.1 - 2 8.6 17.7 0.24 11.6 0.9 3.6 1 1 1 3 3 3 0 Tup N-terminal APG6 PF04111.7 EGG02625.1 - 2.1 7.3 31.4 1.3 7.9 8.0 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 EGG02625.1 - 7.1 7.0 22.8 0.52 10.6 0.5 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) ADIP PF11559.3 EGG02625.1 - 7.3 6.4 33.6 0.52 10.2 5.9 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 EGG02625.1 - 8.1 6.8 28.7 4.6 7.6 2.2 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF904) DAO PF01266.19 EGG02628.1 - 7e-18 64.6 0.0 5e-13 48.6 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGG02628.1 - 0.0023 17.9 0.1 0.0076 16.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGG02628.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MBF1 PF08523.5 EGG02628.1 - 0.028 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Multiprotein bridging factor 1 FAD_binding_2 PF00890.19 EGG02628.1 - 0.048 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Glyco_hydro_63 PF03200.11 EGG02629.1 - 9.6e-238 791.0 0.2 7.2e-237 788.1 0.1 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EGG02629.1 - 2.7e-06 26.3 0.9 7.7e-06 24.8 0.1 1.8 2 0 0 2 2 2 1 Trehalase Bac_rhamnosid PF05592.6 EGG02629.1 - 0.017 13.3 0.0 0.029 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase PQ-loop PF04193.9 EGG02630.1 - 4.6e-38 128.5 14.4 1.4e-19 69.3 0.6 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EGG02630.1 - 0.00073 19.3 5.2 0.072 12.9 0.3 3.0 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange HEV_ORF1 PF02444.11 EGG02631.1 - 0.12 12.5 0.9 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) DUF488 PF04343.8 EGG02631.1 - 0.57 10.5 5.9 0.56 10.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF488 Glycos_trans_3N PF02885.12 EGG02632.1 - 0.096 12.2 0.3 0.22 11.1 0.2 1.5 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain DUF605 PF04652.11 EGG02633.1 - 2.2 7.5 13.5 3.1 7.0 9.4 1.2 1 0 0 1 1 1 0 Vta1 like Bacteriocin_IIi PF11758.3 EGG02634.1 - 0.016 14.7 0.2 0.041 13.4 0.1 1.8 1 1 0 1 1 1 0 Aureocin-like type II bacteriocin Motilin_ghrelin PF04644.7 EGG02639.1 - 3.3 7.6 5.2 0.66 9.8 0.2 2.4 3 0 0 3 3 3 0 Motilin/ghrelin PPDK_N PF01326.14 EGG02642.1 - 0.07 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain SAP PF02037.22 EGG02643.1 - 1.5e-05 24.3 0.5 0.15 11.5 0.1 3.6 3 0 0 3 3 3 2 SAP domain HeH PF12949.2 EGG02643.1 - 0.00057 19.3 1.1 0.46 10.0 0.0 4.3 4 0 0 4 4 4 1 HeH/LEM domain DUF3530 PF12048.3 EGG02645.1 - 0.11 11.4 13.3 0.13 11.1 5.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Mucin PF01456.12 EGG02645.1 - 0.62 9.8 45.9 0.083 12.6 12.7 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein TFIIA PF03153.8 EGG02645.1 - 7.9 6.2 9.3 2.7 7.8 1.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit UBN2 PF14223.1 EGG02646.1 - 0.026 14.3 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF1759 PF03564.10 EGG02646.1 - 0.032 14.0 0.0 0.091 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF4219 PF13961.1 EGG02646.1 - 0.42 10.1 2.4 0.79 9.2 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) RXT2_N PF08595.6 EGG02647.1 - 0.00081 19.2 1.8 0.0012 18.6 1.2 1.2 1 0 0 1 1 1 1 RXT2-like, N-terminal Mpp10 PF04006.7 EGG02647.1 - 0.0078 14.6 3.3 0.01 14.2 2.3 1.1 1 0 0 1 1 1 1 Mpp10 protein DPBB_1 PF03330.13 EGG02647.1 - 0.0081 16.1 0.2 0.03 14.3 0.2 1.9 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Nucleoplasmin PF03066.10 EGG02647.1 - 0.025 14.1 3.6 0.46 9.9 3.5 2.1 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EGG02647.1 - 0.051 13.8 9.6 0.099 12.8 6.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain EBV-NA3 PF05009.7 EGG02647.1 - 0.46 9.6 2.3 0.67 9.1 1.6 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PBP1_TM PF14812.1 EGG02647.1 - 0.51 10.6 3.9 0.97 9.7 2.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 EGG02647.1 - 2.5 5.8 7.8 3.1 5.5 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family Hist_deacetyl PF00850.14 EGG02648.1 - 2.3e-49 168.3 0.0 2.9e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain TctB PF07331.6 EGG02650.1 - 3 7.4 6.7 5.9 6.5 1.9 2.0 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF802 PF05650.6 EGG02651.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF802) tRNA-synt_1 PF00133.17 EGG02652.1 - 4.6e-14 51.3 0.0 5.2e-14 51.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EGG02652.1 - 0.031 12.9 0.0 0.036 12.7 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) DUF3734 PF12536.3 EGG02652.1 - 0.057 13.5 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 Patatin phospholipase NAP PF00956.13 EGG02653.1 - 1.2e-56 191.5 4.6 1.2e-56 191.5 3.2 2.8 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) FliT PF05400.8 EGG02653.1 - 0.077 13.4 0.1 2 8.8 0.0 2.8 3 0 0 3 3 3 0 Flagellar protein FliT Cwf_Cwc_15 PF04889.7 EGG02653.1 - 0.61 9.7 13.1 3.4 7.3 0.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 EGG02653.1 - 2.9 7.4 17.5 6.2 6.3 6.9 2.6 2 0 0 2 2 2 0 Nucleoplasmin RXT2_N PF08595.6 EGG02653.1 - 4.6 7.0 9.4 7.8 6.2 3.1 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleocap_ssRNA PF11128.3 EGG02654.1 - 0.0043 16.5 0.3 0.0055 16.1 0.2 1.1 1 0 0 1 1 1 1 Plant viral coat protein nucleocapsid ExbD PF02472.11 EGG02657.1 - 0.23 11.4 0.9 0.55 10.2 0.4 1.7 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR DUF406 PF04175.7 EGG02658.1 - 0.097 13.1 1.0 0.15 12.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF406) Per1 PF04080.8 EGG02659.1 - 3.6e-14 52.8 0.1 4.2e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Per1-like Biotin_lipoyl PF00364.17 EGG02661.1 - 2.8e-14 52.5 3.2 5.3e-14 51.6 2.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EGG02661.1 - 4.2e-06 26.3 4.8 0.0014 18.2 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 EGG02661.1 - 0.00019 21.7 0.0 0.56 10.5 0.0 2.6 3 0 0 3 3 3 2 HlyD family secretion protein NQRA PF05896.6 EGG02661.1 - 0.0043 16.2 0.3 0.0057 15.8 0.2 1.2 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.14 EGG02661.1 - 0.01 15.5 0.9 0.043 13.4 0.2 1.9 1 1 1 2 2 2 0 Glycine cleavage H-protein RnfC_N PF13375.1 EGG02661.1 - 0.011 15.4 0.7 0.019 14.6 0.5 1.5 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.17 EGG02661.1 - 0.2 11.7 1.0 9.6 6.3 0.0 2.6 1 1 2 3 3 3 0 Peptidase family M23 Toxin_21 PF08091.6 EGG02662.1 - 0.047 13.4 0.2 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Spider insecticidal peptide Cwf_Cwc_15 PF04889.7 EGG02663.1 - 0.015 15.0 3.9 0.018 14.7 2.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-T PF15511.1 EGG02663.1 - 0.055 12.7 2.9 0.06 12.5 2.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DnaJ PF00226.26 EGG02664.1 - 7.6e-20 70.4 0.2 2.9e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EGG02664.1 - 1.3e-08 34.3 3.3 2.2e-08 33.6 1.6 1.9 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EGG02664.1 - 0.00017 21.2 1.1 0.0047 16.7 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGG02664.1 - 0.0025 17.3 0.3 0.44 10.2 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGG02664.1 - 0.011 15.6 1.7 0.03 14.2 1.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGG02664.1 - 0.012 16.1 0.7 1.3 9.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGG02664.1 - 0.012 16.2 3.7 0.046 14.3 0.5 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGG02664.1 - 0.017 15.4 0.9 0.15 12.4 0.2 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGG02664.1 - 0.06 13.8 1.7 0.98 10.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Band_7 PF01145.20 EGG02665.1 - 1.1e-11 44.9 3.9 1.7e-11 44.3 2.7 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family Alpha_GJ PF03229.8 EGG02666.1 - 3.7 7.9 6.2 0.16 12.3 0.3 1.7 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF3077 PF11275.3 EGG02667.1 - 0.067 13.1 0.0 6.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3077) SapB_2 PF03489.12 EGG02668.1 - 0.099 12.6 0.0 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Saposin-like type B, region 2 NARP1 PF12569.3 EGG02670.1 - 6.6e-45 153.8 0.1 7.2e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 EGG02670.1 - 0.00098 19.5 0.6 0.0037 17.7 0.4 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGG02670.1 - 0.0026 17.3 0.2 0.0046 16.5 0.1 1.4 1 0 0 1 1 1 1 TPR repeat NatB_MDM20 PF09797.4 EGG02670.1 - 0.024 13.3 0.3 0.45 9.1 0.0 2.0 1 1 1 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_1 PF00515.23 EGG02670.1 - 0.029 13.9 0.1 0.067 12.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGG02670.1 - 0.034 13.9 0.5 0.2 11.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGG02670.1 - 0.043 13.7 1.2 0.072 13.0 0.2 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Phage_term_smal PF05944.7 EGG02670.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Phage small terminase subunit TPR_6 PF13174.1 EGG02670.1 - 0.12 12.8 0.9 18 6.0 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.3 EGG02671.1 - 1.7e-05 23.7 0.1 1.8e-05 23.7 0.1 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 Myb_DNA-bind_3 PF12776.2 EGG02672.1 - 0.0017 18.9 0.0 0.003 18.1 0.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Asp_protease_2 PF13650.1 EGG02677.1 - 0.0035 17.8 0.0 0.018 15.5 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Transferase PF02458.10 EGG02679.1 - 0.057 11.8 0.2 0.073 11.5 0.1 1.1 1 0 0 1 1 1 0 Transferase family C2 PF00168.25 EGG02680.1 - 7.8e-19 67.3 0.0 8.6e-14 51.1 0.0 2.6 2 0 0 2 2 2 2 C2 domain Ferric_reduct PF01794.14 EGG02682.1 - 8e-18 64.7 8.0 8e-18 64.7 5.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EGG02682.1 - 1.9e-14 53.8 0.0 1.4e-13 51.0 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGG02682.1 - 1e-12 47.8 0.0 2.1e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 EGG02682.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain RNase_H2-Ydr279 PF09468.5 EGG02684.1 - 0.095 11.8 9.9 0.11 11.6 6.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) zf-C2H2_jaz PF12171.3 EGG02684.1 - 0.19 11.9 4.3 0.25 11.5 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding YqfQ PF14181.1 EGG02684.1 - 0.45 10.5 13.7 0.97 9.4 9.5 1.5 1 0 0 1 1 1 0 YqfQ-like protein Glyco_hydro_2 PF00703.16 EGG02684.1 - 3.1 8.3 8.0 21 5.6 3.6 2.3 2 0 0 2 2 2 0 Glycosyl hydrolases family 2 GAGA_bind PF06217.7 EGG02684.1 - 4.8 7.0 12.8 3.3 7.5 7.4 1.7 2 0 0 2 2 2 0 GAGA binding protein-like family vATP-synt_E PF01991.13 EGG02684.1 - 5.1 6.3 19.6 9.6 5.4 13.6 1.4 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Sec62 PF03839.11 EGG02684.1 - 8.1 5.7 14.7 1.5 8.1 7.8 1.6 2 0 0 2 2 2 0 Translocation protein Sec62 Pkinase PF00069.20 EGG02686.1 - 2.7e-55 187.3 0.0 3.4e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG02686.1 - 1e-30 106.7 0.0 1.4e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG02686.1 - 7.2e-05 21.8 0.0 0.00015 20.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGG02686.1 - 0.041 12.7 0.1 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EGG02686.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGG02686.1 - 0.088 12.5 0.0 0.21 11.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EGG02687.1 - 2.8e-57 193.8 2.2 5.9e-38 130.4 0.4 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGG02687.1 - 1e-26 93.5 0.6 1.7e-18 66.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGG02687.1 - 2e-06 26.9 0.2 0.00031 19.8 0.0 3.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EGG02687.1 - 7.9e-05 22.5 1.2 0.0003 20.6 0.8 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 EGG02687.1 - 0.0014 19.1 0.3 0.0045 17.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.9 EGG02687.1 - 0.0078 15.2 0.1 0.043 12.8 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EGG02687.1 - 0.042 12.6 0.0 0.072 11.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RRM_1 PF00076.17 EGG02691.1 - 8.6e-14 50.9 0.0 1.5e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG02691.1 - 9.3e-10 38.3 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG02691.1 - 2.9e-06 27.0 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PH PF00169.24 EGG02692.1 - 1.2e-09 38.2 0.3 2.7e-09 37.1 0.2 1.5 1 0 0 1 1 1 1 PH domain zf-C2H2 PF00096.21 EGG02693.1 - 1.7e-11 43.7 8.4 2.6e-06 27.4 0.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG02693.1 - 8.1e-08 32.1 10.1 8.7e-07 28.9 0.5 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGG02693.1 - 1.6e-05 24.8 6.4 0.0028 17.8 0.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGG02693.1 - 0.0038 17.3 1.7 1.6 8.9 0.2 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGG02693.1 - 0.036 14.2 3.4 0.3 11.3 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGG02693.1 - 0.044 13.7 4.8 0.36 10.7 0.3 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 EGG02693.1 - 0.096 12.5 4.1 1.7 8.5 0.2 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain CHORD PF04968.7 EGG02693.1 - 0.17 12.1 3.1 0.34 11.1 2.2 1.6 1 1 0 1 1 1 0 CHORD zf-BED PF02892.10 EGG02693.1 - 0.32 10.7 2.8 8.5 6.2 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 EGG02693.1 - 0.77 9.7 5.0 28 4.7 0.3 2.1 1 1 1 2 2 2 0 Zinc ribbon domain Zn_clus PF00172.13 EGG02695.1 - 3.9e-05 23.4 2.8 5.5e-05 22.9 2.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KIF1B PF12423.3 EGG02695.1 - 0.2 11.6 0.8 0.44 10.6 0.3 1.7 2 0 0 2 2 2 0 Kinesin protein 1B Sugar_tr PF00083.19 EGG02696.1 - 2.2e-41 141.9 9.0 2.7e-41 141.5 6.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG02696.1 - 1.6e-23 82.9 7.3 1.6e-23 82.9 5.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1206 PF06724.6 EGG02696.1 - 0.056 13.2 2.8 0.081 12.6 0.2 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) CN_hydrolase PF00795.17 EGG02697.1 - 4e-27 94.7 0.0 5.7e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_4 PF13418.1 EGG02697.1 - 0.037 13.8 0.0 0.15 11.8 0.0 2.0 1 1 0 1 1 1 0 Galactose oxidase, central domain SWIM PF04434.12 EGG02698.1 - 0.13 11.7 0.4 0.22 11.0 0.3 1.3 1 0 0 1 1 1 0 SWIM zinc finger Peptidase_M24 PF00557.19 EGG02699.1 - 1.2e-32 113.2 0.0 1.6e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EGG02699.1 - 2.2e-22 79.9 0.0 9.5e-18 64.9 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain RNA_pol_A_bac PF01000.21 EGG02702.1 - 4.3e-27 94.4 0.0 7.9e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGG02702.1 - 8.8e-14 50.3 0.0 1.3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 EGG02702.1 - 0.11 11.9 0.0 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF22 TYW3 PF02676.9 EGG02704.1 - 2e-43 147.9 0.0 2.6e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 ATP-synt_D PF01813.12 EGG02705.1 - 3.7e-68 228.9 5.3 4.5e-68 228.6 3.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit D DUF1054 PF06335.7 EGG02705.1 - 0.015 14.9 0.7 2.4 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) Whi5 PF08528.6 EGG02705.1 - 0.042 13.4 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Whi5 like DUF1664 PF07889.7 EGG02705.1 - 0.21 11.4 2.6 0.34 10.7 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Mem_trans PF03547.13 EGG02708.1 - 3.9e-35 120.8 7.2 6.8e-34 116.7 5.0 2.6 1 1 0 1 1 1 1 Membrane transport protein DUF3923 PF13061.1 EGG02708.1 - 0.015 15.1 2.3 2.8 7.8 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) CAP59_mtransfer PF11735.3 EGG02710.1 - 8.1e-71 238.0 0.0 1.1e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 HSP70 PF00012.15 EGG02711.1 - 1.3e-258 858.9 14.2 1.4e-258 858.7 9.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGG02711.1 - 3.5e-12 45.5 3.6 7.1e-10 37.9 1.6 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EGG02711.1 - 0.00024 20.9 5.0 2.1 8.1 2.5 4.2 1 1 1 2 2 2 2 Cell division protein FtsA TerB PF05099.8 EGG02711.1 - 0.013 15.1 1.7 0.041 13.6 1.2 1.8 1 0 0 1 1 1 0 Tellurite resistance protein TerB Aminotran_5 PF00266.14 EGG02721.1 - 1.2e-23 83.4 0.0 1.6e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGG02721.1 - 2.9e-08 33.0 0.0 4.9e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II RTX_C PF08339.5 EGG02721.1 - 0.071 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 RTX C-terminal domain AAA_5 PF07728.9 EGG02722.1 - 1.5e-103 342.2 0.0 2.1e-23 82.6 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EGG02722.1 - 1.6e-25 89.8 0.0 0.00019 21.6 0.0 8.3 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EGG02722.1 - 9.4e-23 80.2 0.0 8.2e-10 38.3 0.0 6.3 7 0 0 7 7 5 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGG02722.1 - 1.7e-19 70.8 0.7 0.0074 17.1 0.0 7.5 7 0 0 7 7 6 2 AAA domain AAA_22 PF13401.1 EGG02722.1 - 1.2e-18 67.4 0.0 0.25 11.4 0.0 7.8 7 0 0 7 7 6 5 AAA domain AAA_18 PF13238.1 EGG02722.1 - 2e-17 63.6 10.8 0.015 15.5 0.0 8.0 7 1 1 8 8 6 4 AAA domain AAA_16 PF13191.1 EGG02722.1 - 3.1e-17 63.1 18.1 0.0021 18.0 0.2 8.7 9 0 0 9 9 7 4 AAA ATPase domain AAA_14 PF13173.1 EGG02722.1 - 3.7e-17 62.4 0.0 0.0018 18.1 0.0 7.6 7 1 0 7 7 7 3 AAA domain Sigma54_activ_2 PF14532.1 EGG02722.1 - 1.2e-15 57.7 1.9 0.00047 20.2 0.0 6.8 6 1 0 6 6 6 2 Sigma-54 interaction domain AAA_33 PF13671.1 EGG02722.1 - 7.5e-14 51.8 0.0 0.12 12.2 0.0 6.9 6 0 0 6 6 6 3 AAA domain Sigma54_activat PF00158.21 EGG02722.1 - 1e-13 51.0 0.0 0.2 11.1 0.0 5.5 5 0 0 5 5 5 4 Sigma-54 interaction domain T2SE PF00437.15 EGG02722.1 - 5.1e-13 48.5 1.6 0.096 11.5 0.0 5.7 5 0 0 5 5 5 4 Type II/IV secretion system protein Zeta_toxin PF06414.7 EGG02722.1 - 5.3e-13 48.5 0.1 0.081 12.0 0.0 6.0 6 0 0 6 6 5 3 Zeta toxin Miro PF08477.8 EGG02722.1 - 1.8e-12 47.7 1.2 2.1 8.8 0.0 6.9 6 0 0 6 6 6 1 Miro-like protein AAA_19 PF13245.1 EGG02722.1 - 1.5e-11 43.8 0.2 0.13 12.0 0.0 5.8 5 0 0 5 5 5 2 Part of AAA domain AAA_29 PF13555.1 EGG02722.1 - 1.3e-10 40.6 0.8 2.2 7.8 0.0 6.7 6 0 0 6 6 6 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGG02722.1 - 1.7e-10 40.3 2.3 0.93 8.6 0.0 6.1 6 0 0 6 6 6 3 Protein of unknown function, DUF258 AAA_28 PF13521.1 EGG02722.1 - 4.8e-10 39.6 6.7 0.71 9.8 0.0 6.8 6 0 0 6 6 6 3 AAA domain UPF0079 PF02367.12 EGG02722.1 - 7.8e-10 38.4 0.0 1.9 8.1 0.0 6.8 7 0 0 7 7 7 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EGG02722.1 - 1.1e-09 38.3 0.0 7.8 6.7 0.0 7.0 6 0 0 6 6 6 0 RNA helicase DUF815 PF05673.8 EGG02722.1 - 3.9e-09 35.8 0.9 0.047 12.6 0.0 4.9 5 0 0 5 5 5 3 Protein of unknown function (DUF815) MobB PF03205.9 EGG02722.1 - 1.6e-08 34.3 0.2 15 5.2 0.0 6.4 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EGG02722.1 - 2.4e-08 33.9 0.2 0.42 10.2 0.0 5.9 5 0 0 5 5 5 1 Archaeal ATPase VWA_2 PF13519.1 EGG02722.1 - 6.9e-07 29.5 0.3 0.0005 20.2 0.1 2.9 2 0 0 2 2 2 1 von Willebrand factor type A domain ABC_tran PF00005.22 EGG02722.1 - 1.2e-06 28.8 11.0 0.33 11.2 0.1 7.0 7 0 0 7 7 6 2 ABC transporter Mg_chelatase PF01078.16 EGG02722.1 - 1.6e-06 27.4 2.7 15 4.6 0.0 8.2 8 2 2 10 10 9 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EGG02722.1 - 3.4e-06 26.5 0.0 1.4 8.2 0.0 5.0 5 0 0 5 5 5 2 IstB-like ATP binding protein ATP_bind_1 PF03029.12 EGG02722.1 - 1.9e-05 24.3 0.2 0.1 12.0 0.0 4.6 4 0 0 4 4 4 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EGG02722.1 - 2.4e-05 24.2 1.8 15 5.5 0.0 6.3 6 0 0 6 6 6 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGG02722.1 - 6e-05 22.5 0.3 12 5.3 0.0 5.3 6 0 0 6 6 5 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 EGG02722.1 - 8.4e-05 22.0 0.5 4.2 6.7 0.0 5.7 6 0 0 6 6 5 0 AAA domain CPT PF07931.7 EGG02722.1 - 0.0002 21.0 5.7 1.9 8.0 0.0 6.6 7 1 0 7 7 6 1 Chloramphenicol phosphotransferase-like protein PhoH PF02562.11 EGG02722.1 - 0.00023 20.4 0.0 0.9 8.7 0.0 3.3 3 0 0 3 3 3 2 PhoH-like protein RuvB_N PF05496.7 EGG02722.1 - 0.0003 19.9 0.0 2.4 7.1 0.0 5.1 6 0 0 6 6 4 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 EGG02722.1 - 0.0011 18.7 2.7 2.1 8.0 0.0 5.4 6 0 0 6 6 6 1 NTPase AAA_7 PF12775.2 EGG02722.1 - 0.0018 17.4 0.0 0.17 10.9 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 TIP49 PF06068.8 EGG02722.1 - 0.0019 17.0 0.3 5.9 5.4 0.1 4.2 5 0 0 5 5 5 0 TIP49 C-terminus VWA PF00092.23 EGG02722.1 - 0.004 16.8 1.3 0.15 11.7 0.1 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EGG02722.1 - 0.0045 16.8 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus IPT PF01745.11 EGG02722.1 - 0.0059 15.8 0.5 2.5 7.2 0.0 3.5 4 0 0 4 4 4 1 Isopentenyl transferase AAA_24 PF13479.1 EGG02722.1 - 0.0081 15.7 0.0 47 3.4 0.0 4.5 5 0 0 5 5 4 0 AAA domain SRP54 PF00448.17 EGG02722.1 - 0.017 14.6 0.1 8 5.8 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_6 PF12774.2 EGG02722.1 - 1.7 8.1 0.0 92 2.4 0.0 3.4 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region D1 UQ_con PF00179.21 EGG02723.1 - 5.5e-49 165.2 0.0 6.3e-49 165.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGG02723.1 - 4.4e-07 29.7 0.0 5.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGG02723.1 - 0.14 12.0 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain Hepar_II_III PF07940.8 EGG02724.1 - 3e-08 33.6 0.4 7.5e-08 32.3 0.3 1.7 1 0 0 1 1 1 1 Heparinase II/III-like protein TraT PF05818.7 EGG02724.1 - 0.14 11.5 0.2 0.3 10.4 0.2 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF1628 PF07790.6 EGG02724.1 - 0.4 11.4 2.6 2.1 9.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) Ogr_Delta PF04606.7 EGG02725.1 - 0.037 13.6 0.5 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Lectin_N PF03954.9 EGG02725.1 - 0.11 11.9 0.9 0.24 10.7 0.3 1.7 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain PGG PF13962.1 EGG02725.1 - 0.71 9.5 4.4 0.74 9.4 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function TFIIA_gamma_C PF02751.9 EGG02726.1 - 5.7e-09 35.6 2.6 2.1e-05 24.2 0.1 2.2 1 1 1 2 2 2 2 Transcription initiation factor IIA, gamma subunit zf-dskA_traR PF01258.12 EGG02726.1 - 0.1 12.3 2.8 0.37 10.5 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger LRR_4 PF12799.2 EGG02727.1 - 0.031 13.9 2.4 4.9 6.8 0.1 3.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGG02727.1 - 0.18 12.1 1.1 23 5.7 0.0 4.0 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.2 EGG02728.1 - 0.0042 16.7 0.2 0.017 14.8 0.1 1.9 2 0 0 2 2 2 1 F-box-like HHH_2 PF12826.2 EGG02728.1 - 0.12 12.2 0.0 5.1 7.0 0.0 3.6 4 1 1 5 5 5 0 Helix-hairpin-helix motif DPBB_1 PF03330.13 EGG02732.1 - 2.1e-10 40.4 0.1 4.5e-10 39.3 0.1 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGG02732.1 - 8.3e-05 22.2 0.1 0.00011 21.8 0.1 1.3 1 1 0 1 1 1 1 Barwin family NDUFA12 PF05071.11 EGG02733.1 - 1.2e-24 86.7 1.6 1.4e-24 86.5 1.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Ferric_reduct PF01794.14 EGG02734.1 - 9.7e-18 64.4 8.0 9.7e-18 64.4 5.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGG02734.1 - 4.9e-14 52.0 0.0 1.2e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EGG02734.1 - 2.9e-07 30.5 0.0 0.00013 21.8 0.0 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ni_hydr_CYTB PF01292.15 EGG02734.1 - 0.017 14.5 0.4 0.017 14.5 0.3 1.9 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 DUF1514 PF07438.6 EGG02734.1 - 0.12 12.2 0.8 0.3 11.0 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) Mpp10 PF04006.7 EGG02742.1 - 0.62 8.3 11.3 1 7.6 7.8 1.2 1 0 0 1 1 1 0 Mpp10 protein Methyltransf_11 PF08241.7 EGG02750.1 - 1.7e-09 38.0 0.0 2.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG02750.1 - 8.1e-09 35.3 0.0 2.9e-08 33.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG02750.1 - 1.2e-06 28.9 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG02750.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG02750.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EGG02750.1 - 0.016 14.3 0.0 0.027 13.5 0.0 1.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EGG02750.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.2 EGG02750.1 - 0.059 13.9 0.0 0.28 11.7 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGG02750.1 - 0.06 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DLIC PF05783.6 EGG02751.1 - 5.5e-49 167.1 5.4 1.1e-31 110.1 0.0 4.6 4 1 0 4 4 4 4 Dynein light intermediate chain (DLIC) Miro PF08477.8 EGG02751.1 - 0.0045 17.4 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG02751.1 - 0.2 10.8 0.2 0.51 9.5 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family Peptidase_S8 PF00082.17 EGG02753.1 - 3.9e-32 111.5 0.0 9.2e-32 110.3 0.0 1.6 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EGG02753.1 - 2.4e-12 47.2 1.0 5.2e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) PA PF02225.17 EGG02753.1 - 3.3e-09 36.3 0.0 3.9e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 PA domain RNase_H2-Ydr279 PF09468.5 EGG02754.1 - 0.44 9.6 4.9 0.5 9.5 3.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) IncA PF04156.9 EGG02754.1 - 1.7 8.1 5.5 2.1 7.8 3.8 1.1 1 0 0 1 1 1 0 IncA protein DAP PF15228.1 EGG02754.1 - 6.6 7.5 7.8 1.7 9.4 2.9 1.7 2 0 0 2 2 2 0 Death-associated protein PI3_PI4_kinase PF00454.22 EGG02755.1 - 6.9e-51 172.9 0.1 1.5e-50 171.8 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 EGG02755.1 - 6.9e-20 71.0 0.1 3.6e-19 68.6 0.0 2.5 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.18 EGG02755.1 - 5.8e-14 51.8 0.0 1.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.3 EGG02755.1 - 0.0044 16.9 0.1 0.11 12.4 0.0 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF3385) COX15-CtaA PF02628.10 EGG02756.1 - 3.4e-87 292.1 4.7 4.3e-87 291.7 3.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein tRNA_m1G_MT PF01746.16 EGG02758.1 - 1.3e-35 122.6 1.4 2.2e-34 118.6 0.9 2.1 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Sugar_tr PF00083.19 EGG02759.1 - 1.7e-122 409.2 24.3 2e-122 409.0 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG02759.1 - 9.2e-26 90.3 59.1 5.4e-22 77.9 21.2 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Btz PF09405.5 EGG02760.1 - 0.0018 18.3 14.5 0.0018 18.3 10.1 3.9 4 1 0 4 4 4 1 CASC3/Barentsz eIF4AIII binding CCDC-167 PF15188.1 EGG02760.1 - 0.23 11.4 1.3 0.49 10.3 0.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Peptidase_S24 PF00717.18 EGG02762.1 - 7.5e-08 31.9 0.9 2.1e-07 30.4 0.2 2.0 2 1 0 2 2 2 1 Peptidase S24-like EVE PF01878.13 EGG02762.1 - 0.056 13.4 0.0 0.07 13.1 0.0 1.3 1 1 0 1 1 1 0 EVE domain TIP41 PF04176.8 EGG02764.1 - 9.5e-62 207.4 0.0 1.2e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Glyco_hydro_18 PF00704.23 EGG02766.1 - 1.5e-62 212.0 0.1 6.8e-62 209.9 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 EGG02766.1 - 0.078 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Glyco_hydro_19 PF00182.14 EGG02770.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Chitinase class I Telomerase_RBD PF12009.3 EGG02772.1 - 3.6e-13 49.5 1.7 3.6e-13 49.5 1.2 1.6 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain DUF2564 PF10819.3 EGG02773.1 - 0.093 12.8 0.7 0.25 11.4 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) FAD_binding_3 PF01494.14 EGG02775.1 - 8.7e-81 271.7 0.0 4.8e-80 269.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGG02775.1 - 2.1e-45 154.3 0.0 3.5e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EGG02775.1 - 0.00016 20.2 0.1 0.00028 19.4 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EGG02775.1 - 0.00038 19.4 0.1 0.00055 18.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGG02775.1 - 0.00048 20.0 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 EGG02775.1 - 0.0012 18.6 0.1 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 ThiF family Thi4 PF01946.12 EGG02775.1 - 0.002 17.2 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EGG02775.1 - 0.0024 17.8 0.0 0.0061 16.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGG02775.1 - 0.0025 17.8 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGG02775.1 - 0.0073 14.9 0.1 0.011 14.4 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.19 EGG02775.1 - 0.0086 15.0 0.2 0.014 14.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGG02775.1 - 0.011 14.7 0.1 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EGG02775.1 - 0.027 14.5 0.1 0.06 13.4 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EGG02775.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EGG02775.1 - 0.095 11.5 0.1 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EGG02775.1 - 0.14 12.5 0.1 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EGG02775.1 - 0.16 10.7 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.16 EGG02775.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Kisspeptin PF15152.1 EGG02776.1 - 0.048 14.3 0.0 0.068 13.8 0.0 1.2 1 0 0 1 1 1 0 Kisspeptin PAP_central PF04928.12 EGG02779.1 - 4.3e-103 343.5 0.0 5.5e-103 343.1 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EGG02779.1 - 1.4e-36 125.4 0.0 2e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EGG02779.1 - 3.2e-09 36.9 0.0 1.1e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Abhydrolase_2 PF02230.11 EGG02780.1 - 6.9e-28 97.5 0.0 2.1e-27 95.9 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGG02780.1 - 3.6e-05 23.5 0.0 0.00012 21.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG02780.1 - 0.00058 19.8 0.0 0.0049 16.7 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGG02780.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Sushi PF00084.15 EGG02781.1 - 0.0093 16.3 0.5 0.0093 16.3 0.3 2.5 3 0 0 3 3 3 1 Sushi domain (SCR repeat) ODV-E18 PF10717.4 EGG02781.1 - 0.085 12.3 1.0 1.1 8.6 0.1 2.3 2 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF4098 PF13345.1 EGG02783.1 - 7.7e-07 28.9 6.0 0.00012 21.9 3.8 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4098) FRQ PF09421.5 EGG02786.1 - 0.13 10.0 1.4 0.15 9.7 1.0 1.1 1 0 0 1 1 1 0 Frequency clock protein Pox_Ag35 PF03286.9 EGG02788.1 - 0.057 12.9 12.3 0.17 11.4 8.5 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Serinc PF03348.10 EGG02788.1 - 0.13 10.9 0.1 0.23 10.1 0.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) FLO_LFY PF01698.11 EGG02788.1 - 0.14 10.9 7.0 0.25 10.1 4.8 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3362 PF11842.3 EGG02788.1 - 0.59 10.0 4.9 0.13 12.2 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3362) Vfa1 PF08432.5 EGG02788.1 - 1.4 8.9 15.1 3.7 7.5 10.5 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.3 EGG02788.1 - 2 7.0 11.8 3.5 6.2 8.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 WD40 PF00400.27 EGG02789.1 - 8.1e-65 212.5 11.6 2.2e-10 40.0 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EGG02789.1 - 2.8e-11 42.2 8.1 0.0072 14.5 0.3 5.4 1 1 3 5 5 5 5 Nucleoporin Nup120/160 DUF1258 PF06869.7 EGG02789.1 - 0.008 15.2 0.1 0.14 11.1 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1258) Nucleoporin_N PF08801.6 EGG02789.1 - 0.012 14.3 3.2 4.7 5.8 2.2 3.5 1 1 0 1 1 1 0 Nup133 N terminal like Myb_DNA-bind_6 PF13921.1 EGG02790.1 - 0.00066 19.7 0.4 0.038 14.0 0.0 3.4 2 1 1 3 3 3 1 Myb-like DNA-binding domain Phage_int_SAM_1 PF02899.12 EGG02793.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain HTH_3 PF01381.17 EGG02793.1 - 0.019 14.7 0.0 0.87 9.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix Phage_int_SAM_4 PF13495.1 EGG02793.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Indigoidine_A PF04227.7 EGG02794.1 - 8.9e-112 373.0 0.5 1e-111 372.8 0.3 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein MerR_2 PF13591.1 EGG02794.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein ETC_C1_NDUFA5 PF04716.9 EGG02796.1 - 2e-13 49.6 0.1 4.3e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 ETC complex I subunit conserved region Pox_T4_C PF04490.7 EGG02798.1 - 0.017 14.8 0.1 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Poxvirus T4 protein, C terminus DUF2733 PF10813.3 EGG02798.1 - 0.076 12.5 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) YjcZ PF13990.1 EGG02799.1 - 0.14 11.2 3.8 0.049 12.7 0.3 2.0 2 0 0 2 2 2 0 YjcZ-like protein AAA_23 PF13476.1 EGG02800.1 - 7e-19 68.9 0.3 1.4e-18 67.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EGG02800.1 - 9.6e-14 51.1 0.6 1.7e-13 50.3 0.2 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGG02800.1 - 2.7e-07 30.8 0.1 4.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EGG02800.1 - 0.00011 21.3 0.1 0.00013 21.2 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EGG02800.1 - 0.0012 18.2 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EGG02800.1 - 0.032 13.6 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGG02800.1 - 0.046 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EGG02800.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein SMC_N PF02463.14 EGG02801.1 - 8.1e-07 28.4 0.0 9.2e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Helicase_C_2 PF13307.1 EGG02802.1 - 5.1e-53 179.4 0.0 1.2e-52 178.2 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EGG02802.1 - 2.1e-43 147.7 0.0 6.3e-43 146.1 0.0 1.9 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 EGG02802.1 - 1.4e-05 25.0 0.5 0.33 10.7 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EGG02802.1 - 0.0088 14.8 0.2 0.084 11.6 0.1 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain PhoH PF02562.11 EGG02802.1 - 0.028 13.6 0.0 8.1 5.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 EGG02802.1 - 0.042 13.9 0.0 2.6 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain stn_TNFRSF12A PF12191.3 EGG02804.1 - 0.043 13.8 0.1 0.15 12.1 0.1 1.9 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain UPRTase PF14681.1 EGG02804.1 - 0.094 11.9 0.4 0.2 10.8 0.1 1.7 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase Vac7 PF12751.2 EGG02805.1 - 0.004 16.0 1.2 0.0086 14.9 0.4 1.7 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 NUFIP1 PF10453.4 EGG02807.1 - 2.8e-11 42.7 0.1 9.5e-11 41.0 0.0 1.9 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EGG02807.1 - 3.9e-05 23.2 0.2 7e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1033 PF06279.6 EGG02807.1 - 0.023 14.4 0.3 0.064 13.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) HTH_Tnp_Tc5 PF03221.11 EGG02807.1 - 0.032 14.0 0.1 0.063 13.0 0.1 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain zf-CCCH_2 PF14608.1 EGG02807.1 - 0.75 9.8 6.3 0.1 12.6 0.5 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Cyt-b5 PF00173.23 EGG02808.1 - 1.5e-22 79.1 0.0 1.6e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GTP_EFTU PF00009.22 EGG02812.1 - 1.8e-38 131.8 2.3 1.1e-37 129.3 1.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGG02812.1 - 7.9e-26 90.0 1.8 2e-25 88.7 0.3 2.3 2 0 0 2 2 2 1 Translation-initiation factor 2 PduV-EutP PF10662.4 EGG02812.1 - 8.4e-07 28.5 2.1 1.5e-05 24.4 0.6 2.9 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EGG02812.1 - 2.6e-06 27.3 0.0 6.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EGG02812.1 - 2.5e-05 24.3 2.9 0.073 13.2 0.1 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 Ras PF00071.17 EGG02812.1 - 4.5e-05 22.8 0.0 8.8e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG02812.1 - 0.00026 21.4 0.1 0.00059 20.3 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGG02812.1 - 0.0027 16.9 3.0 0.0037 16.5 0.1 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 EGG02812.1 - 0.0032 17.8 3.4 0.47 10.7 0.0 2.7 3 0 0 3 3 3 2 AAA domain FeoB_N PF02421.13 EGG02812.1 - 0.041 13.1 0.1 0.12 11.6 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 EGG02812.1 - 0.086 12.0 0.0 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGG02812.1 - 0.61 9.8 3.1 3.9 7.2 0.0 2.9 2 1 1 3 3 3 0 Dynamin family DUF1649 PF07855.7 EGG02817.1 - 0.33 10.6 1.5 3.4 7.3 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1649) UBN2_2 PF14227.1 EGG02818.1 - 4.2e-07 29.5 0.1 1.4e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGG02818.1 - 0.0065 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type CRA PF06589.6 EGG02819.1 - 0.12 11.6 0.3 0.25 10.6 0.2 1.5 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Cu-oxidase_2 PF07731.9 EGG02820.1 - 0.069 12.6 0.2 0.09 12.2 0.1 1.3 1 0 0 1 1 1 0 Multicopper oxidase DUF4119 PF13494.1 EGG02820.1 - 0.46 10.4 2.8 0.69 9.9 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Herpes_LMP2 PF07415.6 EGG02820.1 - 0.52 8.8 3.4 0.65 8.5 2.4 1.0 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DapH_N PF08503.5 EGG02821.1 - 0.031 14.3 2.6 0.053 13.6 1.4 1.7 1 1 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal BBS2_C PF14782.1 EGG02821.1 - 0.13 10.7 10.2 0.16 10.5 7.1 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DUF2345 PF10106.4 EGG02821.1 - 0.35 10.4 4.9 0.46 10.0 3.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) DUF2125 PF09898.4 EGG02821.1 - 0.78 8.9 5.4 0.96 8.6 3.7 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2125) YwpF PF14183.1 EGG02821.1 - 2.5 7.8 7.2 2.1 8.0 1.4 2.1 1 1 1 2 2 2 0 YwpF-like protein HALZ PF02183.13 EGG02821.1 - 4.3 7.1 11.1 2.4 7.9 0.8 3.0 2 1 1 3 3 3 0 Homeobox associated leucine zipper Yippee-Mis18 PF03226.9 EGG02823.1 - 4.9e-21 74.5 0.1 5.4e-21 74.4 0.0 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RNA_pol_N PF01194.12 EGG02823.1 - 0.099 12.6 1.1 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit DZR PF12773.2 EGG02823.1 - 0.13 12.0 0.4 0.69 9.7 0.2 1.9 1 1 0 1 1 1 0 Double zinc ribbon Mpp10 PF04006.7 EGG02824.1 - 5.6e-69 233.0 9.4 6.1e-69 232.9 6.5 1.0 1 0 0 1 1 1 1 Mpp10 protein Prp18 PF02840.10 EGG02825.1 - 1.8e-57 193.2 1.6 2.8e-57 192.6 0.0 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EGG02825.1 - 5.8e-12 44.6 5.4 1.1e-11 43.7 3.8 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like GFO_IDH_MocA PF01408.17 EGG02826.1 - 2.2e-22 79.7 0.0 4.1e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF521 PF04412.8 EGG02826.1 - 0.01 14.4 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Adaptin_N PF01602.15 EGG02827.1 - 4.9e-113 378.2 0.2 6.3e-113 377.8 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EGG02827.1 - 1e-54 184.4 0.1 2.1e-54 183.4 0.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EGG02827.1 - 2.2e-13 50.3 2.3 0.00057 20.1 0.1 5.8 2 2 4 6 6 6 4 HEAT repeats HEAT PF02985.17 EGG02827.1 - 0.00066 19.5 5.4 1.6 8.9 0.1 5.8 6 0 0 6 6 6 1 HEAT repeat DUF3730 PF12530.3 EGG02827.1 - 0.01 15.7 1.2 0.14 12.0 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3730) Cnd1 PF12717.2 EGG02827.1 - 0.022 14.5 9.9 0.11 12.2 0.1 4.2 2 2 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EGG02827.1 - 0.4 11.2 3.7 2.7 8.6 0.3 3.4 2 1 1 3 3 3 0 HEAT-like repeat Alpha_kinase PF02816.13 EGG02828.1 - 0.0042 16.7 0.1 0.0062 16.2 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family DUF4420 PF14390.1 EGG02830.1 - 0.037 12.8 0.5 0.058 12.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4420) Glyco_transf_34 PF05637.7 EGG02830.1 - 0.11 11.9 0.1 0.36 10.2 0.1 1.8 1 1 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family PqiA PF04403.8 EGG02831.1 - 0.046 13.2 0.2 0.092 12.3 0.1 1.4 1 0 0 1 1 1 0 Paraquat-inducible protein A Lipoprotein_10 PF03202.8 EGG02832.1 - 0.051 13.6 2.9 0.089 12.8 2.0 1.3 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region Baculo_11_kDa PF06143.6 EGG02833.1 - 1.5 8.2 6.9 0.15 11.4 0.4 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family PgaD PF13994.1 EGG02833.1 - 6.3 6.2 9.4 3.1 7.2 0.3 3.2 2 1 1 3 3 3 0 PgaD-like protein Med3 PF11593.3 EGG02834.1 - 0.011 15.0 5.9 0.013 14.7 4.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DNA_pol_viral_N PF00242.12 EGG02834.1 - 0.46 9.4 6.2 0.51 9.3 4.3 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain RR_TM4-6 PF06459.7 EGG02834.1 - 5.6 6.7 13.6 6.5 6.5 9.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NST1 PF13945.1 EGG02836.1 - 5.6 6.9 8.4 8.2 6.4 5.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Mago-bind PF09282.5 EGG02838.1 - 0.038 13.5 8.9 2.1 8.0 0.1 3.3 3 0 0 3 3 3 0 Mago binding SspK PF08176.7 EGG02838.1 - 0.25 11.3 5.5 10 6.2 0.1 3.3 3 0 0 3 3 3 0 Small acid-soluble spore protein K family DUF4002 PF13164.1 EGG02839.1 - 0.002 18.0 2.8 0.0024 17.8 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4002) FAD_binding_3 PF01494.14 EGG02844.1 - 2.7e-83 279.9 0.0 1.3e-82 277.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGG02844.1 - 1.4e-45 154.9 0.0 2.5e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 EGG02844.1 - 0.00015 21.6 0.1 0.00034 20.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGG02844.1 - 0.00021 20.3 0.1 0.0003 19.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGG02844.1 - 0.00024 19.6 0.1 0.00043 18.8 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein ThiF PF00899.16 EGG02844.1 - 0.0011 18.8 0.1 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family Pyr_redox_3 PF13738.1 EGG02844.1 - 0.0012 18.9 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGG02844.1 - 0.0023 16.9 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGG02844.1 - 0.0029 16.7 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EGG02844.1 - 0.0066 16.3 0.1 0.015 15.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGG02844.1 - 0.011 14.3 0.1 0.018 13.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EGG02844.1 - 0.014 14.3 0.1 0.026 13.4 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EGG02844.1 - 0.069 13.2 0.1 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EGG02844.1 - 0.075 11.8 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EGG02844.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EGG02844.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EGG02844.1 - 0.17 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.16 EGG02844.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SPO22 PF08631.5 EGG02845.1 - 3e-08 33.1 11.1 0.00017 20.8 0.0 5.2 4 1 1 5 5 5 4 Meiosis protein SPO22/ZIP4 like Abhydrolase_2 PF02230.11 EGG02846.1 - 6.9e-28 97.5 0.0 2.1e-27 95.9 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGG02846.1 - 3.6e-05 23.5 0.0 0.00012 21.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG02846.1 - 0.00057 19.8 0.0 0.0049 16.7 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGG02846.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) UCH PF00443.24 EGG02847.1 - 1.4e-48 165.3 0.0 4.1e-48 163.8 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGG02847.1 - 5.3e-18 65.4 0.0 6.7e-10 38.8 0.0 3.5 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EGG02847.1 - 9.2e-18 63.4 0.1 4.8e-13 48.2 0.0 3.5 3 0 0 3 3 3 2 A repeated domain in UCH-protein Carbpep_Y_N PF05388.6 EGG02847.1 - 0.064 13.4 0.3 0.32 11.1 0.1 2.2 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide Linker_histone PF00538.14 EGG02849.1 - 2e-13 50.2 0.2 2e-13 50.2 0.1 2.6 3 0 0 3 3 3 1 linker histone H1 and H5 family UCH PF00443.24 EGG02850.1 - 7.8e-40 136.6 4.7 1.1e-39 136.2 3.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGG02850.1 - 1.5e-15 57.4 7.7 2e-15 56.9 5.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C2H2_2 PF12756.2 EGG02850.1 - 2.4 8.3 8.7 0.4 10.8 2.1 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Nop53 PF07767.6 EGG02853.1 - 4.2e-31 108.2 23.6 7.3e-31 107.5 16.4 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF769 PF05590.6 EGG02853.1 - 0.021 14.0 0.8 0.091 11.9 0.0 2.1 2 0 0 2 2 2 0 Xylella fastidiosa protein of unknown function (DUF769) CCDC84 PF14968.1 EGG02853.1 - 0.047 13.1 7.2 0.02 14.4 2.9 1.8 2 0 0 2 2 2 0 Coiled coil protein 84 DUF2228 PF10228.4 EGG02853.1 - 2.4 7.6 14.0 4.7 6.6 0.3 2.6 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) DUF1031 PF06275.6 EGG02854.1 - 0.11 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) SURF4 PF02077.10 EGG02855.1 - 1.3e-72 244.3 1.9 1.6e-72 244.1 1.3 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 EGG02855.1 - 0.34 11.3 15.5 2.5 8.6 0.0 3.2 2 1 0 2 2 2 0 DoxX HR_lesion PF05514.6 EGG02855.1 - 0.43 10.3 3.4 0.93 9.3 0.1 2.6 2 2 0 2 2 2 0 HR-like lesion-inducing Peptidase_S10 PF00450.17 EGG02856.1 - 1e-96 324.6 0.4 1.3e-96 324.3 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase ATPase_gene1 PF09527.5 EGG02856.1 - 0.11 12.3 0.8 0.19 11.5 0.6 1.4 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) B_lectin PF01453.19 EGG02858.1 - 8.9e-13 48.1 0.1 2e-07 30.9 0.1 3.0 2 2 1 3 3 3 3 D-mannose binding lectin Beta_helix PF13229.1 EGG02858.1 - 2.2e-05 24.2 0.3 0.0001 22.0 0.2 2.1 1 1 0 1 1 1 1 Right handed beta helix region Glyco_hydro_18 PF00704.23 EGG02859.1 - 1.7e-65 221.7 0.0 2.4e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hyphal_reg_CWP PF11765.3 EGG02859.1 - 0.0088 14.8 0.9 0.014 14.2 0.6 1.2 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal SAM_2 PF07647.12 EGG02860.1 - 0.027 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Glyco_hydro_26 PF02156.10 EGG02861.1 - 0.15 11.4 1.0 11 5.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 26 Gemini_BL1 PF00845.14 EGG02862.1 - 0.072 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Geminivirus BL1 movement protein Rgp1 PF08737.5 EGG02863.1 - 8.4e-63 212.8 0.0 6.2e-61 206.7 0.0 2.8 1 1 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 EGG02863.1 - 5.1e-06 26.6 0.3 0.79 9.8 0.1 3.6 3 1 0 3 3 3 3 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGG02863.1 - 0.0031 17.3 0.1 0.078 12.7 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain RRM_1 PF00076.17 EGG02865.1 - 1.9e-10 40.2 3.8 2.4e-07 30.2 0.1 4.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG02865.1 - 0.00024 20.9 0.0 0.021 14.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG02865.1 - 0.0012 18.7 0.5 0.007 16.3 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1389 PF07146.6 EGG02867.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1389) Peptidase_S8 PF00082.17 EGG02868.1 - 1.7e-44 152.0 1.8 3.2e-44 151.1 1.2 1.4 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EGG02868.1 - 1e-08 35.5 0.2 2.1e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EGG02868.1 - 6.1e-07 29.0 0.1 1.9e-05 24.2 0.0 2.9 3 0 0 3 3 3 1 PA domain DUF2880 PF11082.3 EGG02870.1 - 0.017 14.9 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) Flu_NS2 PF00601.14 EGG02871.1 - 0.71 10.1 4.4 1 9.6 0.7 2.8 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) Hyaluronidase_1 PF07212.6 EGG02876.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Hyaluronidase protein (HylP) CAP_C PF08603.6 EGG02881.1 - 0.016 14.5 0.6 0.02 14.2 0.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal DASH_Dad3 PF08656.5 EGG02886.1 - 0.11 12.2 0.9 0.26 10.9 0.3 1.8 1 1 1 2 2 2 0 DASH complex subunit Dad3 IL34 PF15036.1 EGG02886.1 - 0.11 12.0 0.3 2.7 7.5 0.2 2.1 2 0 0 2 2 2 0 Interleukin 34 Spectrin PF00435.16 EGG02886.1 - 0.24 11.7 2.9 0.57 10.4 1.2 2.1 1 1 1 2 2 2 0 Spectrin repeat Sec2p PF06428.6 EGG02888.1 - 1.2e-10 41.1 9.2 1.2e-10 41.1 6.4 3.0 1 1 2 3 3 3 1 GDP/GTP exchange factor Sec2p Orbi_VP5 PF00901.12 EGG02888.1 - 0.12 10.5 12.5 0.028 12.6 6.2 1.6 1 1 0 1 1 1 0 Orbivirus outer capsid protein VP5 AAA_13 PF13166.1 EGG02888.1 - 7.6 4.8 16.2 13 4.1 11.2 1.2 1 0 0 1 1 1 0 AAA domain Malate_synthase PF01274.17 EGG02889.1 - 7.8e-212 703.9 0.0 8.9e-212 703.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DUF221 PF02714.10 EGG02890.1 - 5.1e-75 252.3 32.6 1.9e-51 174.8 11.2 2.7 1 1 1 2 2 2 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGG02890.1 - 5.3e-29 100.7 4.5 5.3e-29 100.7 3.1 3.1 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport ABC2_membrane PF01061.19 EGG02894.1 - 3.3e-63 212.6 59.5 3.9e-33 114.4 9.4 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGG02894.1 - 2.6e-17 63.3 0.0 1.6e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGG02894.1 - 2.2e-15 56.1 7.3 2.9e-10 39.7 0.0 3.3 3 1 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EGG02894.1 - 0.00053 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EGG02894.1 - 0.0012 17.9 6.5 0.0012 17.9 4.5 3.9 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.1 EGG02894.1 - 0.017 15.0 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EGG02894.1 - 0.018 14.9 0.0 0.39 10.6 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EGG02894.1 - 0.02 14.0 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MAP65_ASE1 PF03999.7 EGG02895.1 - 6.6e-39 134.0 0.4 6.6e-39 134.0 0.3 2.2 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Snapin_Pallidin PF14712.1 EGG02895.1 - 0.016 15.4 1.4 0.063 13.5 1.0 2.1 1 0 0 1 1 1 0 Snapin/Pallidin DUF2681 PF10883.3 EGG02895.1 - 0.052 13.7 1.1 0.19 11.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF619 PF04768.8 EGG02896.1 - 2e-42 144.5 0.0 3.3e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EGG02896.1 - 2.4e-30 105.3 0.0 9.3e-30 103.4 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EGG02896.1 - 7.5e-21 74.7 0.0 1.3e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family GFO_IDH_MocA PF01408.17 EGG02896.1 - 0.013 16.0 0.0 0.058 13.9 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Dor1 PF04124.7 EGG02896.1 - 0.045 12.1 0.0 0.078 11.4 0.0 1.3 1 0 0 1 1 1 0 Dor1-like family DapB_N PF01113.15 EGG02896.1 - 0.11 12.4 0.0 0.39 10.6 0.0 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Fungal_trans PF04082.13 EGG02898.1 - 2.7e-19 69.0 0.4 1e-18 67.1 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EGG02899.1 - 9.5e-11 41.0 0.3 0.00026 19.9 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGG02899.1 - 6.3e-06 25.9 8.6 6.3e-06 25.9 6.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytokin_check_N PF10407.4 EGG02902.1 - 0.016 14.7 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Fungal_trans PF04082.13 EGG02903.1 - 4.8e-16 58.4 0.5 7.4e-16 57.8 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGG02903.1 - 8.9e-05 22.3 8.1 0.00016 21.4 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGG02906.1 - 7.3e-17 61.0 0.6 1.1e-16 60.5 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGG02906.1 - 0.00051 19.8 8.0 0.00098 18.9 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OSTMP1 PF09777.4 EGG02907.1 - 0.078 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF1049 PF06305.6 EGG02907.1 - 0.088 12.2 0.9 0.15 11.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) RAMP PF04901.8 EGG02907.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Receptor activity modifying family EF-1_beta_acid PF10587.4 EGG02908.1 - 0.78 9.9 4.3 1.4 9.1 3.0 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Ribosomal_L38e PF01781.13 EGG02909.1 - 5.8e-27 93.2 0.7 6.5e-27 93.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family COX7C PF02935.11 EGG02909.1 - 0.081 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc NAM-associated PF14303.1 EGG02910.1 - 5.6e-17 62.4 3.3 7e-17 62.1 2.3 1.1 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain DUF3499 PF12005.3 EGG02910.1 - 0.11 12.7 0.5 0.2 11.8 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3499) Syntaxin PF00804.20 EGG02910.1 - 0.23 11.6 6.6 0.74 10.0 1.1 2.4 2 0 0 2 2 2 0 Syntaxin Ras PF00071.17 EGG02911.1 - 4.9e-34 117.0 0.2 5.8e-34 116.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG02911.1 - 2.8e-22 79.4 0.1 1.1e-21 77.4 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGG02911.1 - 4.7e-09 35.7 0.1 5.8e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGG02911.1 - 1e-07 31.3 0.2 1.3e-07 31.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGG02911.1 - 0.0018 17.7 0.0 0.013 14.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGG02911.1 - 0.0051 16.7 0.0 0.0093 15.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGG02911.1 - 0.0094 14.6 1.6 0.031 12.9 0.0 2.2 1 1 2 3 3 3 1 G-protein alpha subunit DLIC PF05783.6 EGG02911.1 - 0.027 13.1 0.9 1.6 7.2 0.1 2.0 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) SRPRB PF09439.5 EGG02911.1 - 0.086 12.0 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pterin_bind PF00809.17 EGG02912.1 - 3.9e-32 111.3 0.0 6.1e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EGG02912.1 - 1.2e-18 67.0 0.0 2.5e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) adh_short PF00106.20 EGG02913.1 - 6.5e-16 58.6 0.5 7.7e-16 58.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG02913.1 - 9.9e-08 31.8 0.3 1.3e-07 31.4 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGG02913.1 - 0.0027 17.4 0.5 0.0035 17.1 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ldh_1_N PF00056.18 EGG02913.1 - 0.0042 16.9 1.0 0.0055 16.5 0.7 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EGG02913.1 - 0.0048 16.5 1.2 0.0071 16.0 0.8 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EGG02913.1 - 0.038 13.5 1.4 0.18 11.3 0.4 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 EGG02913.1 - 0.053 12.5 0.2 0.063 12.3 0.1 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_26 PF13659.1 EGG02913.1 - 0.064 13.2 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 EGG02913.1 - 0.074 12.6 0.2 0.092 12.3 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glucokinase PF02685.11 EGG02913.1 - 0.14 10.9 3.5 1.8 7.3 0.4 2.1 1 1 1 2 2 2 0 Glucokinase MIP PF00230.15 EGG02914.1 - 0.0072 15.8 9.2 0.0087 15.5 2.9 2.5 1 1 1 2 2 2 2 Major intrinsic protein DUF2457 PF10446.4 EGG02915.1 - 5.4 5.6 17.1 9 4.8 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MIP PF00230.15 EGG02916.1 - 0.0027 17.1 1.6 0.014 14.8 0.1 2.1 2 0 0 2 2 2 1 Major intrinsic protein Ribosomal_L13 PF00572.13 EGG02917.1 - 1.3e-40 138.4 0.1 1.5e-40 138.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 ResIII PF04851.10 EGG02918.1 - 5.1e-21 75.3 0.0 1e-20 74.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGG02918.1 - 5.3e-21 74.8 0.0 1.1e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG02918.1 - 7.5e-19 67.3 0.0 1.5e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGG02918.1 - 0.00045 19.0 0.0 0.00074 18.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.4 EGG02918.1 - 0.038 12.9 0.0 0.069 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EGG02918.1 - 0.04 14.0 0.0 0.27 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain Rifin_STEVOR PF02009.11 EGG02919.1 - 0.021 14.5 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family Plasmodium_Vir PF05795.6 EGG02919.1 - 0.072 12.2 0.9 0.12 11.6 0.6 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF202 PF02656.10 EGG02919.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF202) MSC PF09402.5 EGG02919.1 - 0.13 10.9 0.1 0.19 10.4 0.1 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain P12 PF12669.2 EGG02919.1 - 6.7 6.9 6.6 12 6.2 4.6 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family Peptidase_M56 PF05569.6 EGG02920.1 - 0.013 14.4 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 ABC2_membrane_3 PF12698.2 EGG02920.1 - 0.029 13.3 0.2 0.038 13.0 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein TMEM154 PF15102.1 EGG02920.1 - 0.1 12.2 2.3 0.19 11.4 0.1 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF1113 PF06541.6 EGG02920.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1113) p450 PF00067.17 EGG02922.1 - 8.5e-52 176.2 0.0 1.1e-51 175.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Coat_F PF07875.7 EGG02923.1 - 0.029 14.4 0.5 0.083 13.0 0.3 1.8 1 0 0 1 1 1 0 Coat F domain Hrs_helical PF12210.3 EGG02923.1 - 0.084 13.1 2.3 0.17 12.1 0.1 2.7 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate ER_lumen_recept PF00810.13 EGG02926.1 - 0.00015 22.2 0.7 0.00022 21.7 0.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor OGG_N PF07934.7 EGG02927.1 - 4.8e-25 87.8 3.7 4.8e-25 87.8 2.6 1.9 2 1 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EGG02927.1 - 1.1e-11 44.9 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF1313 PF07011.6 EGG02927.1 - 0.085 12.5 1.3 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1313) MAPKK1_Int PF08923.5 EGG02927.1 - 0.12 12.0 0.8 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Mitogen-activated protein kinase kinase 1 interacting AdoHcyase PF05221.12 EGG02928.1 - 4.7e-140 465.1 0.1 5.3e-140 464.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EGG02928.1 - 1.4e-84 281.9 1.0 2.3e-84 281.1 0.7 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EGG02928.1 - 7.7e-09 34.9 0.1 1.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EGG02928.1 - 0.00076 19.1 0.1 0.0015 18.2 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 EGG02928.1 - 0.00092 18.6 0.2 0.0017 17.7 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EGG02928.1 - 0.0014 18.5 0.1 0.0033 17.3 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 EGG02928.1 - 0.0037 16.9 0.3 0.0069 16.0 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGG02928.1 - 0.0066 16.8 0.3 0.018 15.4 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 EGG02928.1 - 0.013 15.7 0.2 0.032 14.4 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.20 EGG02928.1 - 0.015 15.1 0.7 2.2 8.2 0.1 2.4 2 0 0 2 2 2 0 short chain dehydrogenase TetR_N PF00440.18 EGG02928.1 - 0.13 11.8 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family DUF3452 PF11934.3 EGG02929.1 - 0.023 14.0 0.8 0.036 13.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Rap1_C PF11626.3 EGG02929.1 - 0.081 12.8 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rad60-SLD_2 PF13881.1 EGG02936.1 - 4.3e-12 45.8 0.0 7.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGG02936.1 - 0.00044 19.5 0.0 0.0014 18.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.4 EGG02936.1 - 0.043 14.0 0.3 0.99 9.6 0.0 2.3 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Lactamase_B_2 PF12706.2 EGG02938.1 - 1.1e-24 87.0 0.0 1.1e-23 83.7 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EGG02938.1 - 1.4e-09 37.2 0.0 2.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EGG02938.1 - 2.8e-09 36.9 0.1 5.7e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ATP-synt_ab_C PF00306.22 EGG02938.1 - 0.017 15.5 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain ANTH PF07651.11 EGG02940.1 - 2.1e-10 39.8 1.9 4.6e-07 28.8 0.1 3.3 2 1 1 3 3 3 2 ANTH domain p450 PF00067.17 EGG02942.1 - 5.1e-17 61.5 0.0 2e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 SOCS_box PF07525.11 EGG02943.1 - 0.0035 17.1 0.3 0.0092 15.8 0.2 1.7 1 0 0 1 1 1 1 SOCS box DUF2477 PF10631.4 EGG02943.1 - 1.3 9.2 4.9 2.1 8.5 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) zf-RING-like PF08746.6 EGG02943.1 - 3.2 7.8 6.1 0.95 9.5 1.4 2.0 2 0 0 2 2 2 0 RING-like domain DUF1798 PF08807.5 EGG02944.1 - 0.089 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) UPF0227 PF05728.7 EGG02946.1 - 0.019 14.6 0.1 0.042 13.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lumazine_bd PF12870.2 EGG02946.1 - 0.14 12.1 0.5 2.7 8.0 0.0 2.5 2 1 0 2 2 2 0 Lumazine-binding domain ChlI PF13541.1 EGG02946.1 - 0.15 11.6 0.5 0.35 10.4 0.2 1.8 1 1 1 2 2 2 0 Subunit ChlI of Mg-chelatase IncA PF04156.9 EGG02946.1 - 0.81 9.2 3.8 0.79 9.2 2.1 1.4 1 1 0 1 1 1 0 IncA protein PBP PF01161.15 EGG02948.1 - 2.5e-19 69.5 0.2 2.9e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glutaredoxin PF00462.19 EGG02949.1 - 5.7e-16 58.2 0.0 7.9e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DSBA PF01323.15 EGG02949.1 - 0.016 14.8 0.3 1.3 8.5 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF836 PF05768.9 EGG02949.1 - 0.049 13.8 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 EGG02949.1 - 0.082 13.1 0.1 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain zf-C2H2 PF00096.21 EGG02951.1 - 4e-05 23.6 0.4 4e-05 23.6 0.3 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG02951.1 - 0.00031 20.8 0.5 0.00031 20.8 0.4 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGG02951.1 - 0.06 13.5 0.4 0.17 12.0 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Solute_trans_a PF03619.11 EGG02952.1 - 2.8e-95 318.7 7.3 3.4e-95 318.4 5.1 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SNARE PF05739.14 EGG02954.1 - 1e-09 37.9 1.3 1.3e-09 37.5 0.9 1.1 1 0 0 1 1 1 1 SNARE domain CCDC144C PF14915.1 EGG02954.1 - 0.056 12.3 0.8 0.066 12.1 0.5 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Synaptobrevin PF00957.16 EGG02954.1 - 0.57 9.8 3.6 0.69 9.5 1.8 1.7 1 1 0 1 1 1 0 Synaptobrevin Mo25 PF08569.6 EGG02955.1 - 4.3e-118 394.2 13.6 1.7e-110 369.2 5.5 2.0 2 0 0 2 2 2 2 Mo25-like DUF544 PF04424.8 EGG02955.1 - 0.014 15.1 7.6 0.11 12.3 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF544) EspA PF03433.8 EGG02955.1 - 0.13 11.7 4.1 0.034 13.5 0.7 1.6 2 0 0 2 2 2 0 EspA-like secreted protein RepA_N PF06970.6 EGG02955.1 - 0.14 11.9 5.1 0.053 13.3 1.4 2.0 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus Abhydrolase_2 PF02230.11 EGG02956.1 - 1.6e-58 197.7 0.0 1.7e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGG02956.1 - 5.4e-13 48.9 0.0 7.4e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG02956.1 - 2.3e-10 40.7 0.2 6e-07 29.5 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EGG02956.1 - 0.00016 21.1 0.0 0.00037 20.0 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 EGG02956.1 - 0.0039 16.6 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EGG02956.1 - 0.0065 15.7 0.2 0.066 12.4 0.0 2.3 2 1 1 3 3 3 1 Prolyl oligopeptidase family Cutinase PF01083.17 EGG02956.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydro_lipase PF04083.11 EGG02956.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DLH PF01738.13 EGG02956.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family HCV_NS5a_C PF12941.2 EGG02957.1 - 0.032 13.8 0.1 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region TBCA PF02970.11 EGG02958.1 - 5.3e-15 55.2 9.4 8e-15 54.6 6.5 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor A Med19 PF10278.4 EGG02958.1 - 0.013 15.2 1.6 0.018 14.7 1.1 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 MSP7_C PF12948.2 EGG02958.1 - 0.34 11.1 3.3 0.5 10.6 2.3 1.2 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain Glyco_hydro_18 PF00704.23 EGG02959.1 - 1.2e-63 215.7 1.3 1.6e-63 215.2 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Alpha-amylase PF00128.19 EGG02960.1 - 1.1e-23 84.1 0.0 1.5e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain EF-hand_1 PF00036.27 EGG02962.1 - 1.7e-41 136.3 11.4 5e-10 37.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGG02962.1 - 2.7e-36 123.4 2.9 6.5e-20 71.0 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EGG02962.1 - 1.6e-33 114.0 10.2 3.9e-17 61.6 0.2 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EGG02962.1 - 3.8e-31 104.1 6.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGG02962.1 - 1.4e-28 96.9 6.9 4e-07 29.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EGG02962.1 - 1.2e-13 50.7 0.0 2.5e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EGG02962.1 - 3e-10 39.7 0.2 5.1e-05 22.9 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGG02962.1 - 2.6e-08 33.8 0.0 0.00082 19.3 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EGG02962.1 - 4.8e-07 29.2 0.4 0.011 15.3 0.0 3.6 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EGG02962.1 - 4.1e-06 26.6 1.3 1.9e-05 24.5 0.1 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.8 EGG02962.1 - 0.00036 20.1 0.1 0.041 13.4 0.0 2.5 1 1 0 2 2 2 1 Caleosin related protein DUF1103 PF06513.6 EGG02962.1 - 0.00055 19.4 1.7 0.00057 19.3 1.2 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.8 EGG02962.1 - 0.002 17.8 0.2 0.96 9.1 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB EF-hand_like PF09279.6 EGG02962.1 - 0.0037 17.2 0.5 0.023 14.7 0.1 2.3 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like Poly_export PF02563.11 EGG02962.1 - 0.022 14.5 0.1 3.6 7.4 0.0 3.0 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein MotA_activ PF09114.5 EGG02962.1 - 0.039 13.7 0.3 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain RNA_pol_Rpb4 PF03874.11 EGG02962.1 - 0.065 13.2 0.8 1.7 8.6 0.1 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb4 LNS2 PF08235.8 EGG02962.1 - 0.088 12.3 0.1 0.62 9.6 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Toprim_2 PF13155.1 EGG02962.1 - 0.092 13.0 0.2 15 5.9 0.1 2.3 1 1 1 2 2 2 0 Toprim-like VCBS PF13517.1 EGG02962.1 - 1.6 9.1 5.4 30 5.0 0.6 2.7 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_1 PF00036.27 EGG02963.1 - 3.6e-34 113.4 10.5 1.3e-09 36.6 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGG02963.1 - 2e-30 104.7 3.6 6e-15 55.1 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGG02963.1 - 7.1e-26 87.7 5.7 1.2e-09 37.1 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EGG02963.1 - 2.2e-24 84.8 9.8 1.4e-12 46.9 0.4 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EGG02963.1 - 2.9e-22 76.9 8.3 2.2e-07 29.8 0.1 4.5 4 1 0 4 4 4 4 EF hand EF-hand_4 PF12763.2 EGG02963.1 - 3.6e-12 45.9 0.3 3.3e-05 23.5 0.0 2.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGG02963.1 - 1.1e-09 38.2 0.0 0.00068 19.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EGG02963.1 - 1.3e-08 34.5 0.2 0.00025 20.8 0.0 2.5 2 1 1 3 3 3 2 EF-hand domain UPF0154 PF03672.8 EGG02963.1 - 1.3e-05 24.6 0.4 0.2 11.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EGG02963.1 - 5.6e-05 23.0 0.2 0.00068 19.5 0.0 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.8 EGG02963.1 - 0.00077 19.0 0.0 0.013 15.0 0.0 2.2 2 0 0 2 2 2 1 Caleosin related protein SapB_1 PF05184.10 EGG02963.1 - 0.0071 16.1 0.5 0.81 9.5 0.0 3.3 4 0 0 4 4 4 1 Saposin-like type B, region 1 Acetyltransf_11 PF13720.1 EGG02963.1 - 0.018 15.2 0.0 3.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 LNS2 PF08235.8 EGG02963.1 - 0.038 13.5 0.0 0.064 12.8 0.0 1.4 1 1 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) TerB PF05099.8 EGG02963.1 - 0.069 12.8 0.1 2.7 7.7 0.0 2.2 1 1 1 2 2 2 0 Tellurite resistance protein TerB Excalibur PF05901.6 EGG02963.1 - 0.083 13.2 0.0 33 4.9 0.0 3.0 3 0 0 3 3 3 0 Excalibur calcium-binding domain VCBS PF13517.1 EGG02963.1 - 0.91 9.9 9.7 3.4 8.1 4.0 2.7 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_1 PF00036.27 EGG02964.1 - 1.3e-37 124.2 13.3 1.5e-09 36.4 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGG02964.1 - 2.7e-33 113.8 3.6 4e-19 68.5 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGG02964.1 - 1.9e-30 101.9 4.2 1.5e-08 33.7 0.0 4.5 4 2 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EGG02964.1 - 5.4e-29 99.5 10.6 5e-12 45.2 0.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EGG02964.1 - 7e-22 75.7 11.6 2.5e-06 26.5 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.1 EGG02964.1 - 1.5e-12 47.2 0.0 3.8e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EGG02964.1 - 6.4e-11 41.9 0.7 2.6e-05 23.8 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGG02964.1 - 7.5e-08 32.4 0.0 0.002 18.1 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EGG02964.1 - 7.5e-05 22.2 0.4 1.4 8.5 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EGG02964.1 - 0.0056 16.6 1.7 0.029 14.3 0.1 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EGG02964.1 - 0.014 15.1 0.4 2.7 7.7 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB Caleosin PF05042.8 EGG02964.1 - 0.014 14.9 0.2 0.083 12.4 0.1 2.2 1 1 0 1 1 1 0 Caleosin related protein Beta-lactamase2 PF13354.1 EGG02964.1 - 0.017 14.6 0.0 0.044 13.2 0.0 1.7 1 1 1 2 2 2 0 Beta-lactamase enzyme family EF-hand_like PF09279.6 EGG02964.1 - 0.036 14.0 1.3 0.82 9.7 0.1 2.9 2 2 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DUF1880 PF08976.6 EGG02964.1 - 0.038 14.1 0.0 0.77 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) HHA PF05321.6 EGG02964.1 - 0.043 13.9 0.3 0.23 11.6 0.0 2.3 2 0 0 2 2 2 0 Haemolysin expression modulating protein RNA_pol_Rpb4 PF03874.11 EGG02964.1 - 0.44 10.5 1.9 27 4.8 0.1 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb4 Alpha-amylase PF00128.19 EGG02966.1 - 1.1e-19 71.0 1.0 1.9e-16 60.3 0.2 3.2 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EGG02966.1 - 1.2e-14 54.4 0.0 2.1e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EGG02966.1 - 1.5e-06 27.7 0.0 2.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGG02966.1 - 4e-06 27.0 0.0 1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 VCBS PF13517.1 EGG02966.1 - 0.028 14.7 2.5 0.12 12.7 1.7 2.2 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF4639 PF15479.1 EGG02966.1 - 0.23 10.0 0.1 0.43 9.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) YIF1 PF03878.10 EGG02967.1 - 6.8e-75 251.2 0.1 7.6e-75 251.1 0.1 1.0 1 0 0 1 1 1 1 YIF1 YtpI PF14007.1 EGG02967.1 - 0.013 15.4 2.2 0.14 12.1 0.7 2.5 2 0 0 2 2 2 0 YtpI-like protein DUF1981 PF09324.5 EGG02968.1 - 0.091 12.2 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) Mito_carr PF00153.22 EGG02969.1 - 6.4e-55 182.8 3.8 3.3e-19 68.3 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein LRR_4 PF12799.2 EGG02970.1 - 0.02 14.5 8.3 0.54 9.9 0.1 4.5 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Trypan_PARP PF05887.6 EGG02970.1 - 0.057 13.2 20.6 0.093 12.5 14.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) LRR_7 PF13504.1 EGG02970.1 - 0.09 13.0 1.8 72 4.2 0.0 4.6 3 0 0 3 3 3 0 Leucine rich repeat LRR_8 PF13855.1 EGG02970.1 - 0.14 11.9 9.1 1.1 9.1 0.4 4.7 5 1 1 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 EGG02970.1 - 1.7 8.9 8.4 1.7 8.9 0.2 4.1 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.1 EGG02972.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat Frag1 PF10277.4 EGG02974.1 - 0.0023 17.4 2.1 0.0023 17.4 1.4 1.7 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family DUF443 PF04276.7 EGG02974.1 - 0.025 14.0 1.5 0.033 13.6 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) DUF4079 PF13301.1 EGG02974.1 - 0.06 13.3 0.3 0.087 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF4234 PF14018.1 EGG02974.1 - 0.43 10.3 7.8 0.075 12.7 2.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) FSIP1 PF15554.1 EGG02975.1 - 0.12 11.2 3.1 0.18 10.6 2.1 1.1 1 0 0 1 1 1 0 FSIP1 family Dicty_REP PF05086.7 EGG02979.1 - 3.5 5.2 5.0 4.1 5.0 3.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UQ_con PF00179.21 EGG02981.1 - 9.7e-46 154.6 0.0 1.1e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGG02981.1 - 0.00011 21.9 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGG02981.1 - 0.0062 16.2 0.1 0.014 15.0 0.1 1.6 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EGG02981.1 - 0.05 13.4 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain BPL_LplA_LipB PF03099.14 EGG02982.1 - 9.3e-09 35.3 0.0 4.1e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family eIF-1a PF01176.14 EGG02983.1 - 1.2e-27 95.0 0.1 1.6e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Peroxidase_2 PF01328.12 EGG02984.1 - 0.0033 16.1 1.3 0.49 9.0 0.0 2.2 1 1 1 2 2 2 2 Peroxidase, family 2 NTR PF01759.16 EGG02984.1 - 0.069 12.7 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 UNC-6/NTR/C345C module Sel1 PF08238.7 EGG02986.1 - 3.6e-41 138.6 20.4 1.2e-06 28.9 0.1 7.9 6 1 1 7 7 7 7 Sel1 repeat TPR_14 PF13428.1 EGG02986.1 - 3.5 8.5 11.8 0.22 12.2 1.6 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat Ribosomal_L24e PF01246.15 EGG02987.1 - 9.6e-30 102.2 1.3 1.5e-29 101.6 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L24e DUF2796 PF10986.3 EGG02988.1 - 0.019 14.9 1.7 0.023 14.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) CCDC84 PF14968.1 EGG02988.1 - 0.16 11.4 2.0 0.2 11.1 1.4 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 Alpha-amylase PF00128.19 EGG02993.1 - 2.4e-25 89.5 0.0 3.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Bcr-Abl_Oligo PF09036.5 EGG02994.1 - 1.6 8.7 6.8 0.61 10.0 0.3 2.8 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Mito_carr PF00153.22 EGG02995.1 - 1.9e-63 210.2 6.1 4.4e-21 74.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MatC_N PF07158.6 EGG02995.1 - 0.093 12.5 0.6 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus RNase_PH PF01138.16 EGG02996.1 - 6.5e-19 68.5 0.0 1e-18 67.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF3292 PF11696.3 EGG02996.1 - 0.19 9.5 1.4 0.25 9.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Histone PF00125.19 EGG02998.1 - 6.4e-31 106.3 0.4 1e-30 105.6 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGG02998.1 - 1.2e-05 25.4 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGG02998.1 - 0.0039 17.2 0.0 0.0077 16.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGG02998.1 - 0.0051 16.5 0.1 0.0093 15.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated DUF1057 PF06342.7 EGG03000.1 - 0.0043 15.9 0.0 0.033 13.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) RF-1 PF00472.15 EGG03001.1 - 1.5e-37 127.9 7.2 2.7e-37 127.0 5.0 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EGG03001.1 - 8.8e-23 80.2 0.0 2.5e-22 78.7 0.0 1.9 1 0 0 1 1 1 1 PCRF domain SBF PF01758.11 EGG03002.1 - 1.4e-32 112.5 8.2 1.4e-32 112.5 5.7 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family Herpes_glycop_D PF01537.12 EGG03004.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain Rota_VP2 PF05087.7 EGG03005.1 - 0.045 11.6 0.8 0.065 11.1 0.6 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF4321 PF14209.1 EGG03005.1 - 0.5 10.0 2.3 2.6 7.8 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4321) Peptidase_M24 PF00557.19 EGG03006.1 - 3.8e-44 150.7 0.0 5.7e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EGG03006.1 - 9.2e-16 58.5 0.0 2.4e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Oxysterol_BP PF01237.13 EGG03007.1 - 2.9e-45 154.2 0.4 2e-33 115.3 0.7 2.3 2 1 0 2 2 2 2 Oxysterol-binding protein MBOAT_2 PF13813.1 EGG03008.1 - 5.9e-13 48.6 2.3 2e-12 47.0 1.6 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF202 PF02656.10 EGG03008.1 - 0.0065 16.6 1.2 0.22 11.7 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Amino_oxidase PF01593.19 EGG03009.1 - 2e-41 142.5 0.0 2.9e-40 138.7 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGG03009.1 - 1.6e-10 40.8 0.0 3.7e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGG03009.1 - 6.6e-05 21.5 0.8 0.016 13.6 0.0 2.7 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.19 EGG03009.1 - 9.1e-05 21.5 0.0 0.00086 18.3 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGG03009.1 - 0.00026 21.3 0.7 1.1 9.7 0.2 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGG03009.1 - 0.00048 19.0 0.0 0.0063 15.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EGG03009.1 - 0.00068 19.4 0.1 0.0071 16.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EGG03009.1 - 0.00076 18.6 0.0 0.0018 17.4 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EGG03009.1 - 0.00087 19.4 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGG03009.1 - 0.0016 18.3 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGG03009.1 - 0.027 13.1 0.0 0.057 12.0 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EGG03009.1 - 0.032 13.1 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EGG03009.1 - 0.08 11.9 0.1 1.3 7.9 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain K_oxygenase PF13434.1 EGG03009.1 - 0.11 11.4 0.2 11 4.7 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Baculo_PEP_C PF04513.7 EGG03009.1 - 5.1 6.9 8.3 0.77 9.5 0.5 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus p450 PF00067.17 EGG03011.1 - 4.5e-59 200.1 0.0 6e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGG03014.1 - 1.3e-63 215.1 0.0 1.8e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD-oxidase_C PF02913.14 EGG03015.1 - 9.1e-50 169.2 0.0 1.2e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGG03015.1 - 5e-32 110.2 0.3 8.3e-32 109.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain EpuA PF11772.3 EGG03015.1 - 0.11 11.9 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta CagY_I PF14585.1 EGG03016.1 - 2.5 8.0 10.4 0.34 10.8 1.2 2.6 2 1 0 2 2 2 0 CagY type 1 repeat DUF4615 PF15393.1 EGG03016.1 - 4.9 7.4 8.8 0.71 10.1 2.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) Spc7_N PF15402.1 EGG03017.1 - 1.5 6.7 9.4 1.6 6.6 6.5 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Med25 PF11232.3 EGG03018.1 - 0.00015 21.4 0.2 0.00043 19.9 0.1 1.7 1 1 0 1 1 1 1 Mediator complex subunit 25 PTOV activation and synapsin 2 4HBT PF03061.17 EGG03020.1 - 5.5e-10 39.2 0.0 1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 EGG03020.1 - 1.6e-08 34.9 0.0 2.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 EGG03020.1 - 0.034 13.0 0.2 0.053 12.4 0.1 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase SR-25 PF10500.4 EGG03021.1 - 2.4 7.5 10.2 3.5 7.0 7.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Alpha_kinase PF02816.13 EGG03022.1 - 1.6e-08 34.4 0.4 3.9e-08 33.1 0.3 1.6 1 0 0 1 1 1 1 Alpha-kinase family Usp PF00582.21 EGG03023.1 - 3.4e-18 66.1 1.1 4.9e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 Universal stress protein family Acetyltransf_CG PF14542.1 EGG03023.1 - 0.15 11.9 0.1 0.4 10.6 0.1 1.7 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase NOA36 PF06524.7 EGG03023.1 - 9.9 5.3 9.5 22 4.2 6.6 1.5 1 0 0 1 1 1 0 NOA36 protein ThiF PF00899.16 EGG03025.1 - 3.9e-36 123.8 0.0 6e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family DUF1912 PF08930.5 EGG03025.1 - 0.086 12.9 0.6 2.1 8.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) Polysacc_deac_1 PF01522.16 EGG03026.1 - 4.4e-29 100.6 0.0 6.7e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGG03026.1 - 0.00014 20.8 0.0 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 NUDIX PF00293.23 EGG03027.1 - 8.4e-09 35.1 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Polysacc_deac_1 PF01522.16 EGG03028.1 - 5.6e-27 93.8 0.0 1e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGG03028.1 - 0.014 14.2 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Peptidase_S64 PF08192.6 EGG03028.1 - 1.3 7.2 12.1 1.7 6.9 8.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 PAP1 PF08601.5 EGG03028.1 - 3.3 7.2 23.7 4.7 6.7 16.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 DUF572 PF04502.8 EGG03028.1 - 4.9 6.2 9.7 6.9 5.7 6.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) FHIPEP PF00771.15 EGG03029.1 - 0.35 9.1 4.0 0.43 8.8 2.8 1.1 1 0 0 1 1 1 0 FHIPEP family RRM_1 PF00076.17 EGG03031.1 - 7.8e-16 57.4 0.0 1.4e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG03031.1 - 7.3e-14 51.5 0.0 1.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG03031.1 - 4.1e-13 48.9 0.0 5.8e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GLE1 PF07817.8 EGG03034.1 - 1.7e-35 122.2 2.8 1.8e-35 122.1 0.0 2.1 2 0 0 2 2 2 1 GLE1-like protein DUF436 PF04260.7 EGG03034.1 - 0.036 13.5 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF436) Viral_DNA_bp PF00747.12 EGG03034.1 - 0.052 10.7 3.8 0.076 10.2 2.6 1.2 1 0 0 1 1 1 0 ssDNA binding protein adh_short PF00106.20 EGG03038.1 - 1.1e-15 57.9 0.5 1.4e-15 57.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG03038.1 - 1.7e-07 31.1 0.3 2.3e-07 30.6 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGG03038.1 - 0.0044 16.8 0.5 0.0059 16.4 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ldh_1_N PF00056.18 EGG03038.1 - 0.0064 16.3 1.0 0.0088 15.8 0.7 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EGG03038.1 - 0.0073 15.9 1.2 0.011 15.3 0.8 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EGG03038.1 - 0.06 12.8 1.3 0.24 10.9 0.3 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_26 PF13659.1 EGG03038.1 - 0.098 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glucokinase PF02685.11 EGG03038.1 - 0.33 9.6 3.8 2.7 6.6 0.5 2.1 1 1 1 2 2 2 0 Glucokinase MIP PF00230.15 EGG03040.1 - 0.0012 18.4 1.9 0.0077 15.7 0.1 2.1 2 0 0 2 2 2 2 Major intrinsic protein Ribosomal_L13 PF00572.13 EGG03041.1 - 8e-41 139.0 0.1 9.4e-41 138.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Sgf11 PF08209.6 EGG03042.1 - 0.086 12.1 0.2 0.36 10.1 0.0 1.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Baculo_PEP_C PF04513.7 EGG03043.1 - 0.00045 20.0 0.9 0.00084 19.1 0.6 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 EGG03043.1 - 0.0015 18.3 0.7 0.0041 16.9 0.3 1.7 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Apolipoprotein PF01442.13 EGG03043.1 - 0.0026 17.3 0.5 0.0057 16.1 0.4 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4164 PF13747.1 EGG03043.1 - 0.011 15.8 1.7 0.03 14.4 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Lipase_GDSL_3 PF14606.1 EGG03043.1 - 0.05 13.3 0.2 0.084 12.6 0.1 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ApoLp-III PF07464.6 EGG03043.1 - 0.051 13.5 2.2 0.061 13.3 0.7 1.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Ferritin-like PF12902.2 EGG03043.1 - 0.073 12.6 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Ferritin-like NifU_N PF01592.11 EGG03043.1 - 0.11 12.4 0.2 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 NifU-like N terminal domain DUF883 PF05957.8 EGG03043.1 - 0.15 12.4 3.1 0.31 11.4 0.6 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF724 PF05266.9 EGG03043.1 - 0.21 11.2 2.3 1 8.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) NPV_P10 PF05531.7 EGG03043.1 - 0.86 9.9 3.4 6.5 7.0 2.3 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EGG03043.1 - 1 9.1 3.9 3.7 7.3 2.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Tbf5 PF06331.7 EGG03046.1 - 0.0087 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Fungal_trans PF04082.13 EGG03050.1 - 7.4e-08 31.5 0.2 1e-07 31.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2638 PF10937.3 EGG03050.1 - 0.071 14.1 0.4 0.14 13.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) Rpr2 PF04032.11 EGG03053.1 - 1.8e-18 66.1 4.7 4.2e-18 65.0 3.2 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Med12-PQL PF12144.3 EGG03053.1 - 0.71 9.2 3.3 0.91 8.8 0.6 1.9 2 0 0 2 2 2 0 Eukaryotic Mediator 12 catenin-binding domain RNR_inhib PF08591.5 EGG03056.1 - 2.4 9.1 8.4 13 6.7 5.8 2.1 1 1 1 2 2 2 0 Ribonucleotide reductase inhibitor Trypan_PARP PF05887.6 EGG03057.1 - 4 7.2 11.1 5.5 6.8 7.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TP_methylase PF00590.15 EGG03058.1 - 1.2e-38 132.9 0.0 1.9e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases RNA_pol_Rpb2_6 PF00562.23 EGG03059.1 - 7.8e-118 393.5 0.5 1.7e-117 392.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGG03059.1 - 2.1e-53 180.2 1.0 3.4e-53 179.5 0.2 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGG03059.1 - 1e-33 116.3 0.3 2.2e-33 115.2 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EGG03059.1 - 8.5e-31 106.0 0.1 3.7e-30 103.9 0.1 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EGG03059.1 - 1.4e-23 82.4 0.3 1.4e-23 82.4 0.2 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EGG03059.1 - 2.1e-21 75.4 0.0 4.3e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EGG03059.1 - 1.2e-10 41.1 0.6 3.2e-10 39.8 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 EGG03059.1 - 0.012 14.0 0.1 0.022 13.1 0.0 1.3 1 0 0 1 1 1 0 Baculovirus Y142 protein HSP70 PF00012.15 EGG03060.1 - 7.7e-66 222.2 19.9 7.7e-66 222.2 13.8 4.1 2 1 0 2 2 2 1 Hsp70 protein RRM_6 PF14259.1 EGG03061.1 - 1.6e-05 24.7 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGG03061.1 - 1.8e-05 24.2 0.0 4.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG03061.1 - 0.13 12.1 0.0 0.99 9.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lyase_1 PF00206.15 EGG03062.1 - 2e-97 326.1 0.0 3e-97 325.5 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EGG03062.1 - 5e-29 100.1 0.0 1e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Thymidylate_kin PF02223.12 EGG03063.1 - 7e-37 126.6 0.0 8.8e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EGG03063.1 - 6.4e-06 26.2 0.0 7.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG03063.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGG03063.1 - 0.042 13.7 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGG03063.1 - 0.1 13.4 0.0 0.17 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Na_H_Exchanger PF00999.16 EGG03064.1 - 2e-70 237.2 42.5 2.6e-70 236.9 29.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RNA_pol_I_A49 PF06870.7 EGG03066.1 - 1.5e-74 250.8 6.4 1.9e-74 250.5 4.4 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Sin_N PF04801.8 EGG03066.1 - 0.016 14.0 4.1 0.04 12.7 2.8 1.6 1 1 0 1 1 1 0 Sin-like protein conserved region Lyase_aromatic PF00221.14 EGG03067.1 - 4.3e-88 295.8 0.7 5.3e-88 295.5 0.5 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Lyase_aromatic PF00221.14 EGG03068.1 - 6.1e-46 156.8 1.8 6.6e-46 156.7 1.3 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase CFEM PF05730.6 EGG03070.1 - 1.5e-07 31.0 10.9 2.6e-07 30.3 7.6 1.4 1 0 0 1 1 1 1 CFEM domain DUF1573 PF07610.6 EGG03070.1 - 0.07 12.7 1.9 0.64 9.6 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) TSP_1 PF00090.14 EGG03070.1 - 0.95 9.6 6.9 1.8 8.7 4.8 1.5 1 0 0 1 1 1 0 Thrombospondin type 1 domain DUF59 PF01883.14 EGG03071.1 - 5.9e-10 38.9 0.0 1.3e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 Ribos_L4_asso_C PF14374.1 EGG03073.1 - 0.083 12.7 3.8 0.15 11.9 2.3 1.8 1 1 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain DUF1732 PF08340.6 EGG03074.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) Exo_endo_phos PF03372.18 EGG03075.1 - 1.9e-10 41.1 0.0 2.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IATP PF04568.7 EGG03076.1 - 1.1e-09 38.2 0.4 1.2e-09 38.1 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Tektin PF03148.9 EGG03076.1 - 0.0014 17.3 0.7 0.0016 17.0 0.5 1.0 1 0 0 1 1 1 1 Tektin family IncA PF04156.9 EGG03076.1 - 0.11 12.0 0.5 0.12 11.9 0.3 1.1 1 0 0 1 1 1 0 IncA protein EMP24_GP25L PF01105.19 EGG03076.1 - 0.11 12.1 0.2 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD p450 PF00067.17 EGG03077.1 - 2e-48 165.0 0.0 9.6e-38 129.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 TDH PF03347.8 EGG03077.1 - 0.031 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin Ribosomal_S4 PF00163.14 EGG03078.1 - 6.6e-21 74.4 1.2 1.5e-20 73.3 0.6 1.8 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EGG03078.1 - 1.6e-12 46.6 1.1 1.6e-12 46.6 0.8 2.1 2 0 0 2 2 2 1 S4 domain DUF1754 PF08555.5 EGG03080.1 - 6.5 7.4 21.6 0.36 11.4 5.1 2.4 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) RasGEF PF00617.14 EGG03082.1 - 6.5e-32 110.7 0.0 6.9e-31 107.4 0.0 2.4 1 1 0 1 1 1 1 RasGEF domain Gly_radical PF01228.16 EGG03084.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycine radical Saccharop_dh PF03435.13 EGG03085.1 - 3.1e-74 250.2 0.5 1.5e-73 248.0 0.0 2.2 3 0 0 3 3 3 1 Saccharopine dehydrogenase AlaDh_PNT_N PF05222.10 EGG03085.1 - 3.8e-14 52.8 0.0 1e-13 51.4 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EGG03085.1 - 4.3e-12 45.9 0.0 0.00038 20.0 0.0 3.5 3 0 0 3 3 3 3 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.19 EGG03085.1 - 0.00054 20.2 0.1 0.009 16.3 0.0 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EGG03085.1 - 0.0096 15.9 0.4 0.03 14.3 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_7 PF13241.1 EGG03085.1 - 0.034 14.3 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DapB_N PF01113.15 EGG03085.1 - 0.062 13.2 0.3 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus SeqA PF03925.8 EGG03088.1 - 0.075 12.7 1.2 0.097 12.3 0.8 1.2 1 0 0 1 1 1 0 SeqA protein CobT PF06213.7 EGG03088.1 - 0.14 11.2 7.1 0.18 10.9 4.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NAM-associated PF14303.1 EGG03090.1 - 8.8e-07 29.3 1.6 1.5e-06 28.6 1.1 1.4 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain CHASE3 PF05227.8 EGG03090.1 - 2.9 7.5 10.6 4.5 6.9 7.4 1.3 1 0 0 1 1 1 0 CHASE3 domain SGS PF05002.10 EGG03091.1 - 1.1e-28 98.8 7.1 2.3e-28 97.7 4.9 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EGG03091.1 - 2e-17 63.4 1.3 2.4e-17 63.2 0.1 1.8 2 0 0 2 2 2 1 CS domain Pkinase PF00069.20 EGG03102.1 - 2.3e-46 158.0 0.0 4e-44 150.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG03102.1 - 7.9e-28 97.2 0.0 4.5e-17 61.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGG03102.1 - 2.5e-12 46.3 0.0 5.9e-12 45.1 0.0 1.6 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EGG03102.1 - 0.063 12.6 0.9 0.33 10.2 0.1 2.1 2 0 0 2 2 2 0 RIO1 family Cupin_8 PF13621.1 EGG03103.1 - 8.5e-29 100.7 0.1 1.7e-28 99.8 0.1 1.5 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGG03103.1 - 7.1e-05 22.2 0.1 0.00019 20.7 0.0 1.8 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 EGG03103.1 - 0.00021 21.4 0.5 0.016 15.4 0.0 3.2 3 1 0 4 4 4 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EGG03103.1 - 0.062 12.8 0.0 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 Cupin domain DUF1971 PF09313.6 EGG03103.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Phage_connect_1 PF05135.8 EGG03104.1 - 0.018 15.1 2.5 0.028 14.5 1.8 1.3 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein Trypan_PARP PF05887.6 EGG03104.1 - 0.059 13.1 7.3 0.088 12.6 5.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RNase_PH PF01138.16 EGG03104.1 - 0.14 12.4 2.6 0.26 11.6 1.8 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 BUD22 PF09073.5 EGG03104.1 - 0.79 8.7 17.0 0.99 8.4 11.8 1.0 1 0 0 1 1 1 0 BUD22 LPP20 PF02169.11 EGG03104.1 - 8.7 6.5 8.3 5 7.2 0.7 2.2 1 1 0 2 2 2 0 LPP20 lipoprotein MBOAT_2 PF13813.1 EGG03107.1 - 5.8e-13 48.7 1.1 1.4e-12 47.4 0.8 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Defensin_2 PF01097.13 EGG03112.1 - 0.071 12.8 0.4 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Arthropod defensin CBM_14 PF01607.19 EGG03112.1 - 0.31 11.0 4.4 0.42 10.5 1.6 2.2 1 1 1 2 2 2 0 Chitin binding Peritrophin-A domain TPR_11 PF13414.1 EGG03113.1 - 1.1e-12 47.3 0.7 2.2e-12 46.4 0.5 1.5 1 0 0 1 1 1 1 TPR repeat DUF4470 PF14737.1 EGG03113.1 - 3.5e-12 45.9 0.0 1.7e-11 43.7 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4470) TPR_12 PF13424.1 EGG03113.1 - 0.015 15.1 0.5 0.034 14.0 0.2 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGG03113.1 - 0.023 14.5 0.3 0.8 9.7 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RhoGEF PF00621.15 EGG03113.1 - 0.2 11.4 2.0 0.49 10.2 0.1 2.2 2 0 0 2 2 2 0 RhoGEF domain DUF4470 PF14737.1 EGG03114.1 - 4.2e-12 45.6 0.0 9.8e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EGG03114.1 - 3.8e-06 26.4 1.0 7.4e-06 25.5 0.7 1.4 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.1 EGG03114.1 - 0.023 14.6 0.6 0.052 13.4 0.4 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat CtIP_N PF10482.4 EGG03115.1 - 0.028 14.2 0.2 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF2153 PF09921.4 EGG03115.1 - 0.055 13.0 0.1 0.075 12.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) Rhabdo_glycop PF00974.13 EGG03116.1 - 0.0058 14.9 0.0 0.0071 14.6 0.0 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein HOASN PF14515.1 EGG03117.1 - 0.14 12.5 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices PEMT PF04191.8 EGG03118.1 - 9.6e-30 102.8 2.6 1.6e-28 98.9 0.2 2.8 3 0 0 3 3 3 1 Phospholipid methyltransferase YTH PF04146.10 EGG03122.1 - 8.1e-47 158.3 0.2 1.1e-46 157.9 0.1 1.1 1 0 0 1 1 1 1 YT521-B-like domain HLH PF00010.21 EGG03123.1 - 6.1e-14 51.4 2.0 1.8e-13 49.9 1.4 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.13 EGG03123.1 - 0.015 15.0 0.2 0.034 13.8 0.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF3038 PF11237.3 EGG03123.1 - 0.026 14.3 6.1 0.061 13.1 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) DUF1043 PF06295.7 EGG03123.1 - 0.8 9.3 9.4 0.055 13.0 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF3347 PF11827.3 EGG03123.1 - 5.3 7.0 10.9 0.33 10.9 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) WD40 PF00400.27 EGG03124.1 - 9.4e-16 57.0 11.1 1e-05 25.1 0.2 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat UDG PF03167.14 EGG03125.1 - 1.1e-08 34.6 0.2 3.7e-07 29.7 0.0 2.7 2 1 0 2 2 2 1 Uracil DNA glycosylase superfamily Cpn60_TCP1 PF00118.19 EGG03127.1 - 1.8e-138 462.2 11.1 2.3e-138 461.8 7.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EGG03127.1 - 0.017 14.5 0.1 0.046 13.2 0.1 1.7 1 0 0 1 1 1 0 Phage Tail Protein X PTPA PF03095.10 EGG03128.1 - 9.1e-117 389.5 0.2 1.1e-116 389.2 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein H_PPase PF03030.11 EGG03129.1 - 0.43 8.7 2.5 0.6 8.2 1.6 1.3 1 1 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF4257 PF14074.1 EGG03129.1 - 0.56 9.8 4.2 0.51 10.0 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) RDD PF06271.7 EGG03129.1 - 5.2 6.9 12.5 59 3.5 8.7 2.4 1 1 0 1 1 1 0 RDD family 5TM-5TMR_LYT PF07694.7 EGG03129.1 - 9.1 5.5 16.1 1.2 8.4 6.3 2.3 1 1 1 2 2 2 0 5TMR of 5TMR-LYT Pkinase PF00069.20 EGG03132.1 - 8.6e-08 31.6 0.0 0.00047 19.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain DUF4537 PF15057.1 EGG03133.1 - 4.9e-08 32.8 0.2 8.5e-05 22.3 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) PWWP PF00855.12 EGG03133.1 - 2e-06 27.8 0.4 0.0067 16.5 0.1 2.8 2 0 0 2 2 2 2 PWWP domain Pyr_redox_2 PF07992.9 EGG03134.1 - 2e-39 135.5 10.3 2.2e-37 128.8 7.2 3.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EGG03134.1 - 2.1e-39 133.9 0.3 6e-39 132.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EGG03134.1 - 8.3e-24 83.8 7.5 3.1e-20 72.3 0.5 4.0 5 0 0 5 5 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGG03134.1 - 8e-14 51.2 3.0 9.1e-12 44.5 0.1 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 EGG03134.1 - 1.5e-12 47.3 6.9 1.7e-11 43.8 0.0 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGG03134.1 - 3.9e-11 43.3 0.4 6.4e-06 26.3 0.1 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGG03134.1 - 1e-08 35.0 4.9 0.00038 20.4 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGG03134.1 - 1.5e-08 33.9 10.7 0.0016 17.4 0.1 3.4 2 1 1 3 3 3 3 FAD dependent oxidoreductase Thi4 PF01946.12 EGG03134.1 - 2.3e-08 33.4 1.2 3.1e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 EGG03134.1 - 4e-08 32.5 14.7 9.1e-08 31.3 2.0 3.8 2 1 2 4 4 4 1 FAD binding domain HI0933_like PF03486.9 EGG03134.1 - 2.7e-07 29.4 12.9 0.00014 20.4 0.8 4.0 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 EGG03134.1 - 6e-05 22.1 0.5 0.28 10.0 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EGG03134.1 - 0.00068 18.7 9.7 0.019 14.0 0.7 3.0 2 1 0 2 2 2 2 FAD binding domain AlaDh_PNT_C PF01262.16 EGG03134.1 - 0.00085 18.9 1.3 0.063 12.8 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Mqo PF06039.10 EGG03134.1 - 0.0078 14.4 2.9 0.027 12.6 0.2 2.2 1 1 1 2 2 2 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_7 PF13241.1 EGG03134.1 - 0.41 10.9 4.2 5.3 7.3 0.6 3.3 2 1 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EGG03134.1 - 0.68 8.7 7.8 0.52 9.1 0.4 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EGG03134.1 - 1.4 8.5 6.1 0.67 9.5 0.2 2.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Nop14 PF04147.7 EGG03135.1 - 5.8 4.6 13.1 6.9 4.4 9.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGG03135.1 - 9.9 4.0 11.0 12 3.7 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1707 PF08044.6 EGG03137.1 - 0.05 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) NPV_P10 PF05531.7 EGG03137.1 - 0.061 13.5 0.2 0.22 11.7 0.1 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1295 PF06966.7 EGG03138.1 - 1.3e-55 188.2 7.1 1.9e-55 187.7 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EGG03138.1 - 1.1e-06 28.6 0.1 1.7e-05 24.8 0.0 2.6 1 1 1 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 EGG03138.1 - 3e-05 23.8 0.1 3e-05 23.8 0.1 3.1 2 1 0 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 EGG03138.1 - 0.0025 17.9 0.0 0.0098 16.0 0.0 2.0 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family GWT1 PF06423.7 EGG03138.1 - 1.4 9.0 6.0 1.5 8.8 2.0 2.6 1 1 1 2 2 2 0 GWT1 Carn_acyltransf PF00755.15 EGG03140.1 - 5.3e-140 467.3 0.0 6.6e-140 467.0 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Prefoldin PF02996.12 EGG03141.1 - 3.4e-25 88.0 3.6 4.3e-25 87.6 2.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit BCAS3 PF12490.3 EGG03141.1 - 0.024 13.9 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Lebercilin PF15619.1 EGG03141.1 - 0.026 13.9 0.6 0.026 13.9 0.4 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2120 PF09893.4 EGG03141.1 - 0.15 12.0 1.3 0.25 11.3 0.4 1.6 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) ERM PF00769.14 EGG03141.1 - 2 7.8 8.7 1.5 8.2 1.1 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Zn_clus PF00172.13 EGG03144.1 - 1.1e-07 31.6 11.2 1.9e-07 30.8 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3896 PF13035.1 EGG03144.1 - 0.097 12.7 1.6 0.21 11.6 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) PHP_C PF13263.1 EGG03144.1 - 0.18 11.3 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 PHP-associated Shisa PF13908.1 EGG03145.1 - 0.21 11.7 0.1 0.51 10.4 0.0 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RmlD_sub_bind PF04321.12 EGG03146.1 - 7.3e-50 169.4 0.0 1e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EGG03146.1 - 5e-21 75.2 0.0 9.5e-21 74.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGG03146.1 - 2.5e-06 26.6 0.0 3.1e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGG03146.1 - 3.5e-05 23.9 0.5 5.6e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGG03146.1 - 5.2e-05 22.2 0.0 0.0001 21.3 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Cullin_binding PF03556.10 EGG03148.1 - 1.8e-32 111.9 2.6 1e-31 109.4 1.4 2.1 1 1 1 2 2 2 1 Cullin binding PEMT PF04191.8 EGG03149.1 - 2e-52 175.7 11.4 1.5e-31 108.6 1.7 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase AflR PF08493.5 EGG03149.1 - 0.086 11.8 0.4 0.16 10.9 0.3 1.3 1 0 0 1 1 1 0 Aflatoxin regulatory protein Sec3-PIP2_bind PF15277.1 EGG03150.1 - 0.054 13.3 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH OSCP PF00213.13 EGG03152.1 - 0.013 15.3 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit DUF4613 PF15390.1 EGG03152.1 - 0.054 11.6 2.3 0.058 11.5 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF3595 PF12166.3 EGG03152.1 - 0.17 10.7 0.8 0.18 10.6 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) MFS_1 PF07690.11 EGG03153.1 - 2.4e-45 154.8 31.3 9.6e-40 136.3 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EGG03153.1 - 9.6e-06 23.9 6.1 9.6e-06 23.9 4.2 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector PUCC PF03209.10 EGG03153.1 - 0.017 13.8 7.4 0.012 14.3 1.6 2.6 2 2 0 2 2 2 0 PUCC protein Sugar_tr PF00083.19 EGG03153.1 - 0.025 13.1 16.4 0.064 11.8 0.0 3.4 3 1 0 3 3 3 0 Sugar (and other) transporter ALO PF04030.9 EGG03154.1 - 1.5e-66 224.6 0.0 1.9e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EGG03154.1 - 5.4e-25 87.4 0.0 8.6e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Mito_carr PF00153.22 EGG03155.1 - 3.5e-66 218.9 0.7 1.8e-24 85.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CytB6-F_Fe-S PF08802.5 EGG03155.1 - 0.0099 15.8 0.2 0.63 10.0 0.0 2.8 2 0 0 2 2 2 1 Cytochrome B6-F complex Fe-S subunit GFO_IDH_MocA PF01408.17 EGG03158.1 - 5.3e-18 65.6 0.0 9.4e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGG03158.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Myb_DNA-bind_3 PF12776.2 EGG03159.1 - 2.1e-09 37.8 0.4 4.9e-09 36.7 0.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain F-box-like PF12937.2 EGG03162.1 - 0.015 15.0 0.5 0.042 13.5 0.1 2.1 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EGG03162.1 - 0.45 10.2 5.5 0.34 10.6 1.1 2.5 2 0 0 2 2 2 0 F-box domain Gtr1_RagA PF04670.7 EGG03163.1 - 2.7e-63 213.1 0.0 3.4e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGG03163.1 - 0.04 13.8 0.0 0.092 12.7 0.0 1.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase RINT1_TIP1 PF04437.8 EGG03163.1 - 0.1 11.1 0.7 0.21 10.0 0.4 1.5 1 1 1 2 2 2 0 RINT-1 / TIP-1 family FAD_binding_3 PF01494.14 EGG03165.1 - 0.16 11.0 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Vps35 PF03635.12 EGG03167.1 - 0 1060.4 2.3 0 1060.2 1.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF390 PF04094.9 EGG03167.1 - 4.9 5.0 10.8 7.1 4.5 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Cupin_8 PF13621.1 EGG03173.1 - 3.8e-14 52.8 0.0 5.5e-13 48.9 0.0 2.3 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EGG03173.1 - 2.1e-11 44.0 0.2 2.5e-10 40.6 0.1 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box PF00646.28 EGG03173.1 - 0.00049 19.6 1.0 0.0011 18.6 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EGG03173.1 - 0.00093 18.8 1.3 0.002 17.8 0.0 2.2 3 0 0 3 3 3 1 F-box-like Cupin_4 PF08007.7 EGG03173.1 - 0.0033 16.7 0.0 0.0049 16.1 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Gp-FAR-1 PF05823.7 EGG03173.1 - 0.02 14.8 0.7 0.045 13.7 0.5 1.6 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Cupin_2 PF07883.6 EGG03173.1 - 0.079 12.4 0.0 0.41 10.1 0.0 2.1 2 0 0 2 2 2 0 Cupin domain Gaa1 PF04114.9 EGG03174.1 - 3.5e-64 217.3 0.0 2.3e-56 191.5 0.0 2.2 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component Myc_N PF01056.13 EGG03174.1 - 0.13 11.3 0.5 0.25 10.4 0.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region LRR_8 PF13855.1 EGG03175.1 - 0.1 12.3 5.0 11 5.9 0.0 4.4 5 1 0 5 5 5 0 Leucine rich repeat Ribosomal_L21e PF01157.13 EGG03177.1 - 4.4e-36 122.6 4.4 6.8e-36 122.0 3.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e DHH PF01368.15 EGG03178.1 - 1.1e-09 38.1 0.0 2.7e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 DHH family DHHA2 PF02833.9 EGG03178.1 - 0.03 14.5 0.0 0.062 13.5 0.0 1.6 1 1 0 1 1 1 0 DHHA2 domain DUF89 PF01937.14 EGG03179.1 - 8.5e-110 366.8 0.1 9.7e-110 366.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 NST1 PF13945.1 EGG03180.1 - 5.2e-45 153.8 0.0 5.2e-45 153.8 0.0 6.1 5 1 1 6 6 6 3 Salt tolerance down-regulator PfkB PF00294.19 EGG03182.1 - 1.4e-16 60.4 0.0 2.2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EGG03182.1 - 0.0003 20.0 0.0 0.00043 19.5 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Polyketide_cyc PF03364.15 EGG03183.1 - 2.3e-18 66.4 0.0 3.2e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EGG03184.1 - 5.2e-17 62.0 0.0 8.2e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF500 PF04366.7 EGG03185.1 - 1.1e-22 79.8 0.0 8.6e-21 73.6 0.0 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF500) DUF572 PF04502.8 EGG03186.1 - 0.014 14.6 1.8 0.017 14.3 1.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pro-rich PF15240.1 EGG03187.1 - 2.2 8.3 31.7 0.51 10.4 19.8 1.5 2 0 0 2 2 2 0 Proline-rich AKAP2_C PF15304.1 EGG03188.1 - 0.069 12.7 4.2 0.086 12.4 2.9 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus FYVE PF01363.16 EGG03189.1 - 7.6e-19 67.3 0.1 2e-18 66.0 0.0 1.8 1 1 0 1 1 1 1 FYVE zinc finger EAV_GS PF01309.13 EGG03189.1 - 0.047 13.2 0.2 0.079 12.4 0.1 1.3 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein Cep57_MT_bd PF06657.8 EGG03189.1 - 0.07 13.0 4.2 0.18 11.7 0.1 3.2 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Kelch_1 PF01344.20 EGG03190.1 - 0.044 13.3 2.1 2.8 7.5 0.1 3.6 4 0 0 4 4 4 0 Kelch motif PDCD2_C PF04194.8 EGG03191.1 - 3e-27 95.2 8.5 1e-26 93.5 0.4 3.3 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain UCH PF00443.24 EGG03191.1 - 8.2e-06 25.1 0.0 0.00035 19.7 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Myc_N PF01056.13 EGG03191.1 - 0.0037 16.4 2.2 0.0098 15.0 1.6 1.7 1 0 0 1 1 1 1 Myc amino-terminal region DUF1843 PF08898.5 EGG03191.1 - 0.44 10.6 2.5 0.6 10.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Mid1 PF12929.2 EGG03192.1 - 9.1e-69 232.2 1.3 1.4e-68 231.6 0.9 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component zf-CCHC_4 PF14392.1 EGG03193.1 - 0.04 13.5 1.2 0.063 12.9 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle Coq4 PF05019.8 EGG03196.1 - 1e-89 299.2 0.0 1.3e-89 298.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 HEAT PF02985.17 EGG03197.1 - 5.7e-23 78.9 8.9 0.00049 19.9 0.0 11.6 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.1 EGG03197.1 - 3.5e-17 62.3 13.9 1e-09 38.5 0.0 9.0 8 2 1 10 10 10 2 HEAT-like repeat HEAT_2 PF13646.1 EGG03197.1 - 1.9e-16 60.1 9.6 5.6e-06 26.5 0.0 7.4 1 1 5 6 6 6 6 HEAT repeats IBN_N PF03810.14 EGG03197.1 - 4.5e-11 42.4 4.6 7.2e-09 35.4 0.1 4.3 3 1 1 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.18 EGG03197.1 - 7.1e-10 38.3 3.8 0.0058 16.4 0.0 6.0 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat IFRD PF05004.8 EGG03197.1 - 0.0003 19.9 0.5 0.022 13.8 0.1 2.7 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.3 EGG03197.1 - 0.0016 18.3 0.3 0.6 10.0 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) CLASP_N PF12348.3 EGG03197.1 - 0.0024 17.2 0.0 14 4.9 0.0 4.3 4 2 1 5 5 5 1 CLASP N terminal MMS19_C PF12460.3 EGG03197.1 - 1.6 7.3 6.7 1 8.0 0.0 3.1 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal Abhydrolase_6 PF12697.2 EGG03198.1 - 7.6e-05 22.6 0.1 0.00027 20.8 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG03198.1 - 0.028 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2798 PF11391.3 EGG03198.1 - 0.1 12.3 3.3 0.42 10.4 2.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) Capsid-VNN PF11729.3 EGG03200.1 - 0.0061 15.5 0.0 0.0099 14.8 0.0 1.3 1 0 0 1 1 1 1 nodavirus capsid protein SNF2_N PF00176.18 EGG03201.1 - 9.6e-37 126.3 0.0 1.5e-26 92.9 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EGG03201.1 - 2.1e-13 49.9 0.0 2.8e-11 43.1 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG03201.1 - 0.0041 16.9 0.0 0.096 12.5 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit EIID-AGA PF03613.9 EGG03201.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component UQ_con PF00179.21 EGG03203.1 - 2.5e-44 150.0 0.0 2.9e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGG03203.1 - 0.035 13.8 0.0 0.081 12.6 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic E2 family B 60KD_IMP PF02096.15 EGG03204.1 - 4.4e-28 98.2 0.6 6.5e-28 97.7 0.4 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein DUF4291 PF14124.1 EGG03204.1 - 0.064 12.8 0.3 0.1 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) CBS PF00571.23 EGG03205.1 - 4.5e-05 23.1 1.9 7 6.5 0.0 4.3 1 1 3 4 4 4 4 CBS domain TMEM191C PF15194.1 EGG03205.1 - 1.5 8.7 9.2 15 5.4 0.2 3.8 1 1 3 4 4 4 0 TMEM191C family CARDB PF07705.6 EGG03206.1 - 0.073 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 CARDB Ribonuclease_3 PF00636.21 EGG03206.1 - 0.09 13.2 0.5 0.86 10.0 0.4 2.7 1 1 0 1 1 1 0 Ribonuclease III domain FAD_binding_1 PF00667.15 EGG03207.1 - 2e-43 148.4 0.0 3.4e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGG03207.1 - 2.6e-24 85.8 0.0 5.1e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EGG03207.1 - 1.6e-15 57.6 0.0 3.3e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF770 PF05591.7 EGG03207.1 - 0.041 13.4 0.1 0.95 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF770) Glyco_hydro_32N PF00251.15 EGG03208.1 - 2.5e-30 105.8 3.1 4.5e-23 82.0 2.3 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EGG03208.1 - 2.2e-15 56.8 0.0 1.7e-14 53.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal DUF4407 PF14362.1 EGG03209.1 - 3.9 6.3 9.2 4.3 6.1 6.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3414 PF11894.3 EGG03210.1 - 0.016 12.1 0.1 0.019 11.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) IncA PF04156.9 EGG03212.1 - 0.00016 21.3 7.0 0.00021 20.9 4.9 1.1 1 0 0 1 1 1 1 IncA protein zf-RING_5 PF14634.1 EGG03212.1 - 0.00017 21.2 11.9 0.00038 20.1 8.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGG03212.1 - 0.00034 20.3 10.3 0.0007 19.3 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EGG03212.1 - 0.00055 19.5 4.0 0.0013 18.4 2.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 EGG03212.1 - 0.002 17.8 3.6 0.002 17.8 2.5 1.7 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) AIP3 PF03915.8 EGG03212.1 - 0.0033 16.3 6.0 0.0044 15.9 4.2 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 zf-C3HC4_2 PF13923.1 EGG03212.1 - 0.0083 16.1 9.4 0.029 14.4 6.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) bZIP_1 PF00170.16 EGG03212.1 - 0.039 13.9 7.8 1 9.3 1.4 3.0 2 1 1 3 3 3 0 bZIP transcription factor zf-C3HC4_4 PF15227.1 EGG03212.1 - 0.04 13.7 10.5 0.32 10.9 7.5 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING LUC7 PF03194.10 EGG03212.1 - 0.043 13.3 2.5 0.053 13.0 1.7 1.1 1 0 0 1 1 1 0 LUC7 N_terminus zf-C3HC4 PF00097.20 EGG03212.1 - 0.043 13.4 11.6 0.11 12.2 8.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CENP-K PF11802.3 EGG03212.1 - 0.087 12.0 5.4 0.13 11.4 3.7 1.2 1 0 0 1 1 1 0 Centromere-associated protein K TBPIP PF07106.8 EGG03212.1 - 0.096 12.2 9.2 0.22 11.0 6.2 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_11 PF13086.1 EGG03212.1 - 0.19 11.2 5.4 0.28 10.7 3.7 1.2 1 0 0 1 1 1 0 AAA domain DUF3573 PF12097.3 EGG03212.1 - 0.24 9.9 3.2 0.32 9.5 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) BLOC1_2 PF10046.4 EGG03212.1 - 0.31 11.1 10.7 1.8 8.7 4.1 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.4 EGG03212.1 - 0.81 9.5 10.1 1.4 8.7 7.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Viral_P18 PF04521.8 EGG03212.1 - 0.82 9.1 5.1 6.3 6.2 1.1 2.4 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein FYVE PF01363.16 EGG03212.1 - 0.86 9.5 10.3 0.16 11.9 4.6 1.7 2 0 0 2 2 1 0 FYVE zinc finger MbeD_MobD PF04899.7 EGG03212.1 - 1.2 9.0 4.6 5.1 7.0 1.2 2.3 1 1 1 2 2 2 0 MbeD/MobD like Spectrin PF00435.16 EGG03212.1 - 1.5 9.1 7.5 3.5 7.9 4.9 1.7 1 1 0 1 1 1 0 Spectrin repeat HALZ PF02183.13 EGG03212.1 - 1.6 8.4 4.2 15 5.3 1.0 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 EGG03212.1 - 2.1 8.1 13.1 8.3 6.2 6.9 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.10 EGG03212.1 - 2.7 7.5 11.6 2.7 7.5 2.1 3.0 1 1 3 4 4 4 0 Septum formation initiator DUF904 PF06005.7 EGG03212.1 - 4.4 7.6 12.0 8.9e+02 0.2 8.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) TSC22 PF01166.13 EGG03212.1 - 4.9 7.2 8.3 1.3 9.0 1.3 2.8 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF972 PF06156.8 EGG03212.1 - 5.7 7.3 9.3 18 5.7 3.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIVA PF05103.8 EGG03212.1 - 6.2 6.8 10.7 1.3 9.0 4.2 2.0 1 1 1 2 2 2 0 DivIVA protein Kazal_2 PF07648.10 EGG03215.1 - 0.0039 17.0 0.4 0.0092 15.8 0.3 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain NPP1 PF05630.6 EGG03215.1 - 0.094 12.4 2.7 0.12 12.1 1.9 1.2 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Spc97_Spc98 PF04130.8 EGG03217.1 - 0.00045 18.6 2.8 0.00064 18.1 2.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family GP41 PF00517.12 EGG03218.1 - 0.016 14.7 0.4 6.6 6.2 0.1 2.4 2 0 0 2 2 2 0 Retroviral envelope protein Baculo_11_kDa PF06143.6 EGG03218.1 - 0.03 13.6 0.7 0.03 13.6 0.5 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF3382 PF11862.3 EGG03218.1 - 0.057 13.3 0.2 0.057 13.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Acid_PPase PF12689.2 EGG03221.1 - 9.4e-57 191.3 0.0 1.1e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EGG03221.1 - 0.089 13.0 0.0 1.5 8.9 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DcuC PF03606.10 EGG03222.1 - 0.00084 17.6 4.9 0.00084 17.6 3.4 1.4 2 0 0 2 2 2 1 C4-dicarboxylate anaerobic carrier Nodulin_late PF07127.6 EGG03222.1 - 0.22 11.6 3.0 2.3 8.4 0.3 2.9 2 0 0 2 2 2 0 Late nodulin protein Mito_carr PF00153.22 EGG03223.1 - 4.1e-50 167.4 0.1 5e-17 61.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3463 PF11946.3 EGG03224.1 - 0.018 14.6 0.1 24 4.4 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3463) LRR_8 PF13855.1 EGG03225.1 - 0.82 9.4 9.7 1.8 8.3 2.8 3.9 4 1 2 6 6 6 0 Leucine rich repeat LRR_4 PF12799.2 EGG03225.1 - 2.6 7.7 8.7 2.4 7.9 1.6 3.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) ADH_zinc_N PF00107.21 EGG03227.1 - 4.7e-27 94.0 0.2 8e-27 93.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGG03227.1 - 4.4e-07 29.6 0.0 2e-06 27.5 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGG03227.1 - 1.9e-05 25.5 0.0 3.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EGG03227.1 - 0.13 11.7 0.3 0.24 10.9 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Acyl_transf_3 PF01757.17 EGG03229.1 - 5.1e-28 97.8 20.8 9.2e-28 97.0 14.4 1.4 1 1 0 1 1 1 1 Acyltransferase family DUF1335 PF07056.6 EGG03230.1 - 0.1 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) zf-C5HC2 PF02928.11 EGG03230.1 - 0.24 11.4 0.2 0.24 11.4 0.1 2.2 2 1 0 2 2 2 0 C5HC2 zinc finger HlyIII PF03006.15 EGG03231.1 - 1.2e-52 178.5 18.3 1.5e-52 178.2 12.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Multi_Drug_Res PF00893.14 EGG03231.1 - 0.015 15.7 1.0 0.036 14.5 0.2 2.2 2 1 0 2 2 2 0 Small Multidrug Resistance protein Glyco_hydro_63 PF03200.11 EGG03232.1 - 3.8e-07 28.3 4.1 4.5e-05 21.5 0.3 3.9 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase Mucin PF01456.12 EGG03233.1 - 0.0088 15.8 22.3 0.021 14.6 15.5 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein TMEM154 PF15102.1 EGG03233.1 - 2.6 7.7 7.6 3.9 7.1 5.3 1.3 1 0 0 1 1 1 0 TMEM154 protein family Med3 PF11593.3 EGG03233.1 - 5.1 6.2 15.6 6 5.9 10.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIF_alpha PF05793.7 EGG03233.1 - 8.3 4.6 6.5 11 4.1 4.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UQ_con PF00179.21 EGG03235.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme tify PF06200.9 EGG03236.1 - 0.024 13.8 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 tify domain GSG-1 PF07803.6 EGG03237.1 - 0.16 11.6 6.7 0.53 9.9 4.6 1.9 1 1 0 1 1 1 0 GSG1-like protein C1_3 PF07649.7 EGG03237.1 - 0.96 9.5 6.1 1.4 9.0 1.1 2.7 2 0 0 2 2 2 0 C1-like domain DUF1769 PF08588.5 EGG03239.1 - 5.2e-15 55.1 0.1 1.1e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF2922 PF11148.3 EGG03239.1 - 0.078 12.6 0.2 1.7 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) PNGaseA PF12222.3 EGG03240.1 - 6.3e-69 232.8 0.2 2e-68 231.2 0.1 1.7 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A MS_channel PF00924.13 EGG03241.1 - 4.3e-11 42.5 4.7 6.5e-11 41.9 2.2 2.0 1 1 1 2 2 2 1 Mechanosensitive ion channel APG6 PF04111.7 EGG03244.1 - 1.8 7.5 13.2 3 6.8 9.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 EGG03244.1 - 8.7 4.6 9.2 14 3.9 6.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF342 PF03961.8 EGG03244.1 - 8.8 4.6 7.7 14 3.9 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FAR1 PF03101.10 EGG03245.1 - 0.024 15.1 0.3 0.07 13.6 0.2 1.8 1 0 0 1 1 1 0 FAR1 DNA-binding domain Cellulase-like PF12876.2 EGG03246.1 - 0.035 14.5 0.0 0.087 13.2 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like Apolipoprotein PF01442.13 EGG03250.1 - 6.1e-06 25.8 0.0 0.00017 21.1 0.1 2.2 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 EGG03250.1 - 0.00059 19.6 2.7 0.0019 18.0 1.9 1.8 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Senescence PF06911.7 EGG03250.1 - 0.00082 19.1 0.2 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 Senescence-associated protein SF-assemblin PF06705.6 EGG03250.1 - 0.0012 18.1 3.2 0.0023 17.1 1.7 1.7 2 0 0 2 2 2 1 SF-assemblin/beta giardin COG2 PF06148.6 EGG03250.1 - 0.021 14.6 0.5 0.041 13.7 0.3 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 RmuC PF02646.11 EGG03250.1 - 0.049 12.4 0.8 0.16 10.7 0.1 2.0 2 0 0 2 2 2 0 RmuC family Tmemb_cc2 PF10267.4 EGG03250.1 - 0.062 11.8 0.6 0.17 10.4 0.2 1.7 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein ApoLp-III PF07464.6 EGG03250.1 - 0.075 13.0 1.2 0.14 12.1 0.4 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.7 EGG03250.1 - 0.077 12.7 2.4 0.18 11.5 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Lipoprotein_7 PF01540.11 EGG03250.1 - 0.11 11.5 0.9 0.32 10.0 0.5 1.7 2 0 0 2 2 2 0 Adhesin lipoprotein Mst1_SARAH PF11629.3 EGG03250.1 - 2.5 7.9 4.7 7.9 6.3 0.1 3.1 2 1 1 3 3 3 0 C terminal SARAH domain of Mst1 Homeobox PF00046.24 EGG03251.1 - 4.1e-12 45.5 0.7 6e-12 44.9 0.5 1.3 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EGG03251.1 - 0.031 13.3 0.1 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez RNA_pol_Rpb5_C PF01191.14 EGG03251.1 - 0.11 12.0 1.7 3 7.5 0.1 2.4 1 1 1 2 2 2 0 RNA polymerase Rpb5, C-terminal domain Oxidored_q6 PF01058.17 EGG03252.1 - 8.2e-22 77.2 0.1 1.3e-21 76.6 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit UBN2 PF14223.1 EGG03253.1 - 6.8e-10 38.7 0.6 1.4e-09 37.7 0.4 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG03253.1 - 1.3e-08 34.4 1.1 2.7e-08 33.3 0.8 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Det1 PF09737.4 EGG03256.1 - 0.072 11.8 0.3 0.074 11.8 0.2 1.0 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 AA_permease PF00324.16 EGG03258.1 - 2.1e-98 329.7 37.5 2.5e-98 329.5 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGG03258.1 - 2.6e-28 98.7 38.8 3.4e-28 98.3 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGG03259.1 - 5.9e-66 222.7 34.5 1.6e-49 168.5 16.2 4.0 1 1 2 3 3 3 3 Amino acid permease AA_permease_2 PF13520.1 EGG03259.1 - 8.5e-13 47.6 31.6 3e-10 39.2 21.9 3.6 1 1 0 1 1 1 1 Amino acid permease GAF PF01590.21 EGG03260.1 - 3.2e-05 24.1 0.0 0.00021 21.4 0.0 2.2 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 EGG03260.1 - 0.00018 21.6 0.0 0.031 14.3 0.0 2.5 2 0 0 2 2 2 2 GAF domain Pinin_SDK_memA PF04696.8 EGG03263.1 - 4.5e-17 61.8 4.1 4.5e-17 61.8 2.8 2.8 3 1 0 3 3 3 1 pinin/SDK/memA/ protein conserved region HHA PF05321.6 EGG03263.1 - 0.011 15.9 1.7 0.036 14.1 0.2 2.4 2 0 0 2 2 2 0 Haemolysin expression modulating protein FA_desaturase PF00487.19 EGG03265.1 - 1.6e-19 70.4 28.8 1.2e-18 67.5 20.0 2.2 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EGG03265.1 - 8.5e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) EDR1 PF14381.1 EGG03266.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 GST_N PF02798.15 EGG03268.1 - 2.4e-18 66.0 0.0 6.5e-18 64.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGG03268.1 - 4.3e-13 49.0 0.0 1.1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGG03268.1 - 6.1e-13 48.7 0.0 1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGG03268.1 - 4.6e-11 42.5 0.1 8.1e-11 41.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGG03268.1 - 4.8e-05 23.1 0.0 9.2e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGG03268.1 - 0.00029 21.2 0.1 0.00041 20.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EGG03268.1 - 0.042 14.2 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 MetRS-N binding domain adh_short PF00106.20 EGG03271.1 - 0.02 14.8 0.0 0.02 14.8 0.0 1.0 1 0 0 1 1 1 0 short chain dehydrogenase CENP-S PF15630.1 EGG03272.1 - 1.4e-29 102.0 0.5 2e-29 101.5 0.4 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EGG03272.1 - 0.00096 18.5 0.1 0.00096 18.5 0.1 2.5 3 0 0 3 3 3 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EGG03272.1 - 0.0033 17.1 0.2 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 EGG03272.1 - 0.0049 16.6 0.2 0.0087 15.8 0.1 1.4 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EGG03272.1 - 0.12 12.4 0.7 0.29 11.2 0.5 1.8 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CHD5 PF04420.9 EGG03273.1 - 1.2e-45 155.0 1.4 1.4e-45 154.7 1.0 1.1 1 0 0 1 1 1 1 CHD5-like protein WXG100 PF06013.7 EGG03273.1 - 0.12 12.4 0.6 0.17 11.8 0.4 1.2 1 0 0 1 1 1 0 Proteins of 100 residues with WXG TIG PF01833.19 EGG03274.1 - 3.8e-12 46.0 0.0 2e-11 43.7 0.0 2.4 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.2 EGG03274.1 - 3.6e-07 30.4 0.0 7.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGG03274.1 - 1.7e-06 27.5 0.0 0.00022 20.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EGG03274.1 - 2.9e-05 23.8 0.0 0.017 15.3 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EGG03274.1 - 3.3e-05 23.9 0.0 0.014 15.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGG03274.1 - 0.0021 18.4 0.0 1.4 9.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) G-alpha PF00503.15 EGG03275.1 - 1.7e-112 375.9 0.2 2.1e-112 375.6 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGG03275.1 - 1.5e-15 56.9 1.1 1.3e-10 40.8 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGG03275.1 - 0.00039 19.6 3.0 0.0087 15.2 0.1 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGG03275.1 - 0.00068 20.1 0.0 0.048 14.1 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EGG03275.1 - 0.024 14.1 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EGG03275.1 - 0.031 14.2 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EGG03275.1 - 0.035 13.5 0.1 5.1 6.4 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGG03275.1 - 0.091 12.7 0.0 2.1 8.3 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase CPT PF07931.7 EGG03275.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_trans_NIPA PF05653.9 EGG03277.1 - 1e-14 54.2 7.8 1.7e-07 30.5 0.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EGG03277.1 - 1e-06 28.8 5.6 1e-06 28.8 3.9 3.4 3 1 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EGG03277.1 - 9.7e-06 25.7 4.4 9.7e-06 25.7 3.1 3.6 4 0 0 4 4 4 1 Multidrug resistance efflux transporter IncA PF04156.9 EGG03277.1 - 0.22 11.1 2.6 0.43 10.1 0.0 2.6 2 1 0 2 2 2 0 IncA protein DUF2207 PF09972.4 EGG03277.1 - 2.2 6.7 5.0 0.24 9.9 0.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF788 PF05620.6 EGG03277.1 - 5 6.9 5.9 39 4.0 4.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF788) Phasin_2 PF09361.5 EGG03279.1 - 0.00076 19.4 0.3 0.18 11.8 0.1 2.5 2 1 0 2 2 2 2 Phasin protein DUF3347 PF11827.3 EGG03279.1 - 0.34 10.8 6.8 1.5 8.7 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Methyltransf_31 PF13847.1 EGG03281.1 - 3e-15 56.0 0.1 7e-15 54.9 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG03281.1 - 3.3e-11 43.7 0.0 1.1e-10 42.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 EGG03281.1 - 7.8e-11 41.6 0.0 1.1e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 EGG03281.1 - 9e-11 41.3 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 EGG03281.1 - 4.4e-10 39.9 0.0 1.2e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG03281.1 - 1.7e-08 34.3 0.0 4.8e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG03281.1 - 1.8e-08 34.4 0.0 4e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGG03281.1 - 1.3e-07 30.9 0.1 2.5e-07 30.0 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EGG03281.1 - 3.6e-07 29.2 0.1 5.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EGG03281.1 - 3.3e-06 26.5 0.1 6.1e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGG03281.1 - 5.1e-06 26.7 0.0 1.6e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG03281.1 - 1.2e-05 25.6 0.0 2.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGG03281.1 - 0.00099 18.6 0.1 0.0015 17.9 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EGG03281.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 EGG03281.1 - 0.0039 16.7 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 EGG03281.1 - 0.0059 16.2 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.1 EGG03281.1 - 0.0083 16.9 0.0 0.017 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGG03281.1 - 0.0084 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 EGG03281.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 EGG03281.1 - 0.019 14.6 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 EGG03281.1 - 0.08 12.4 0.1 0.16 11.4 0.0 1.5 2 0 0 2 2 1 0 RNA cap guanine-N2 methyltransferase TehB PF03848.9 EGG03281.1 - 0.13 11.3 1.2 0.97 8.5 0.5 2.4 2 1 0 2 2 2 0 Tellurite resistance protein TehB GNAT_acetyltr_2 PF13718.1 EGG03283.1 - 3.5e-76 254.8 0.0 4.2e-75 251.3 0.0 2.4 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EGG03283.1 - 3.7e-62 209.1 0.0 8.4e-62 207.9 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EGG03283.1 - 1.1e-37 127.5 0.1 4.4e-37 125.6 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EGG03283.1 - 2.1e-30 104.7 0.7 8e-30 102.9 0.5 2.1 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 EGG03283.1 - 0.013 15.4 0.0 0.048 13.6 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGG03283.1 - 0.039 14.1 0.0 0.24 11.5 0.0 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain E1-E2_ATPase PF00122.15 EGG03284.1 - 1.3e-27 96.3 0.1 2.9e-27 95.1 0.1 1.6 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EGG03284.1 - 4.8e-23 82.3 0.0 9.2e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 EGG03284.1 - 1.9e-16 59.9 0.5 4.5e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 P5-type ATPase cation transporter Hydrolase PF00702.21 EGG03284.1 - 4.3e-16 59.9 0.0 1.9e-14 54.6 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGG03284.1 - 5.8e-05 22.9 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGG03284.1 - 0.00085 18.7 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Glyco_hydro_61 PF03443.9 EGG03285.1 - 8.4e-23 81.3 0.3 8.4e-23 81.3 0.2 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CFEM PF05730.6 EGG03285.1 - 2.6e-09 36.7 11.3 2.6e-09 36.7 7.8 2.1 2 0 0 2 2 2 1 CFEM domain CDC45 PF02724.9 EGG03290.1 - 0.019 13.0 0.9 0.018 13.0 0.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3391 PF11871.3 EGG03290.1 - 0.019 15.1 4.0 0.043 14.0 2.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) TFIIF_alpha PF05793.7 EGG03290.1 - 0.26 9.6 15.8 0.31 9.3 10.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ORC2 PF04084.9 EGG03291.1 - 3.8e-64 216.6 0.0 4.9e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ORC6 PF05460.8 EGG03291.1 - 1.3 8.0 10.7 2.1 7.3 7.4 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Fasciclin PF02469.17 EGG03292.1 - 6.9e-50 168.3 0.0 9.5e-12 45.0 0.0 5.6 5 1 0 5 5 5 5 Fasciclin domain DUF2201_N PF13203.1 EGG03293.1 - 2.8 7.0 14.2 3 6.9 9.9 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Cation_efflux PF01545.16 EGG03294.1 - 9.6e-77 257.8 7.4 1.3e-76 257.3 5.1 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EGG03294.1 - 1.4e-06 27.5 12.0 2.5e-06 26.7 8.4 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter NicO PF03824.11 EGG03294.1 - 0.01 15.1 0.9 0.01 15.1 0.6 2.6 2 1 0 2 2 2 0 High-affinity nickel-transport protein Macoilin PF09726.4 EGG03294.1 - 0.011 14.0 2.0 0.012 13.9 1.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Glyco_transf_49 PF13896.1 EGG03295.1 - 5e-09 35.6 0.0 0.0001 21.5 0.0 3.1 2 1 1 3 3 3 3 Glycosyl-transferase for dystroglycan Aminotran_1_2 PF00155.16 EGG03296.1 - 4.4e-59 200.2 0.0 5e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Vps5 PF09325.5 EGG03296.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Vps5 C terminal like FYVE_2 PF02318.11 EGG03302.1 - 0.35 10.7 2.8 0.46 10.4 1.9 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger Metallophos PF00149.23 EGG03304.1 - 4.1e-30 104.6 0.0 6.5e-22 77.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase PPP5 PF08321.7 EGG03304.1 - 3.9e-12 46.0 0.0 7.5e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EGG03304.1 - 5e-08 32.4 0.1 5.4e-07 29.1 0.0 2.4 1 1 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EGG03304.1 - 1.7e-06 27.3 0.0 6.6e-05 22.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGG03304.1 - 0.0024 17.5 0.0 0.006 16.2 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGG03304.1 - 0.019 15.1 0.0 1.9 8.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Cu-oxidase PF00394.17 EGG03305.1 - 1e-22 80.7 0.0 4e-21 75.5 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGG03305.1 - 5.8e-22 77.6 0.1 7.8e-21 74.0 0.1 2.5 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG03305.1 - 7.9e-15 54.5 2.7 2e-11 43.5 0.1 4.3 2 2 0 2 2 2 2 Multicopper oxidase Fe_hyd_lg_C PF02906.9 EGG03307.1 - 1.1e-65 221.7 0.1 1.6e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain OB_NTP_bind PF07717.11 EGG03307.1 - 0.026 14.3 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold APC10 PF03256.11 EGG03308.1 - 1e-45 155.7 0.1 2.7e-45 154.3 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EGG03308.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain Zn_clus PF00172.13 EGG03310.1 - 5.8e-08 32.5 13.7 1.1e-07 31.6 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA_gamma_N PF02268.11 EGG03311.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain RHH_1 PF01402.16 EGG03311.1 - 0.12 12.3 0.2 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family HemY_N PF07219.8 EGG03313.1 - 0.0088 15.5 2.6 0.074 12.6 0.3 2.4 2 0 0 2 2 2 1 HemY protein N-terminus ASFV_J13L PF05568.6 EGG03313.1 - 0.1 12.1 1.4 1.7 8.1 0.4 2.3 2 0 0 2 2 2 0 African swine fever virus J13L protein PI3_PI4_kinase PF00454.22 EGG03315.1 - 2.4e-38 131.9 0.3 3.2e-38 131.5 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EGG03315.1 - 1.4e-16 59.5 0.3 5.4e-16 57.7 0.1 2.0 2 0 0 2 2 2 1 FATC domain DUF87 PF01935.12 EGG03319.1 - 0.032 14.0 3.2 0.063 13.0 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 SET PF00856.23 EGG03319.1 - 0.13 12.5 0.1 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 SET domain CHCH PF06747.8 EGG03320.1 - 6.1e-06 26.0 5.2 1.3e-05 24.9 3.6 1.6 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EGG03320.1 - 0.026 14.6 2.4 0.057 13.5 1.7 1.5 1 0 0 1 1 1 0 GCK domain Glyco_hydro_61 PF03443.9 EGG03321.1 - 3e-23 82.8 0.2 5.4e-23 81.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CFEM PF05730.6 EGG03321.1 - 8.3e-07 28.7 6.7 8.3e-07 28.7 4.6 2.1 2 0 0 2 2 2 1 CFEM domain DUF4003 PF13170.1 EGG03322.1 - 0.00072 18.8 0.0 2 7.5 0.0 4.9 3 2 4 7 7 7 2 Protein of unknown function (DUF4003) MARVEL PF01284.18 EGG03323.1 - 1.8e-05 24.6 6.9 2.8e-05 23.9 4.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF805 PF05656.9 EGG03323.1 - 0.2 11.4 4.5 7.1 6.4 2.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF706 PF05153.10 EGG03324.1 - 8.8e-119 395.4 0.6 1e-118 395.1 0.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EGG03324.1 - 0.025 14.6 0.0 0.36 10.8 0.0 2.3 2 0 0 2 2 2 0 HD domain MIF4G PF02854.14 EGG03325.1 - 3.9e-51 173.4 8.1 1.4e-27 96.5 0.0 3.7 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 EGG03325.1 - 5.3e-22 78.3 7.6 5.3e-22 78.3 5.2 2.8 2 1 0 2 2 2 1 Up-frameshift suppressor 2 SNAPc_SNAP43 PF09808.4 EGG03327.1 - 6.4e-07 29.2 0.8 7e-06 25.8 0.1 2.6 2 1 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 CPSF100_C PF13299.1 EGG03329.1 - 6.6e-24 84.9 2.5 2.9e-22 79.5 0.0 3.2 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EGG03329.1 - 1.2e-15 57.5 0.0 6.8e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 EGG03329.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase FAD_binding_8 PF08022.7 EGG03330.1 - 1.5e-18 66.5 0.0 8.1e-17 61.0 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EGG03330.1 - 1.2e-15 57.7 0.0 2.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EGG03330.1 - 3.5e-15 56.1 9.5 3.5e-15 56.1 6.6 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component Amidohydro_2 PF04909.9 EGG03332.1 - 3.9e-07 29.9 0.0 6.6e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase UCH PF00443.24 EGG03333.1 - 2.3e-42 144.9 0.0 2.3e-42 144.9 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGG03333.1 - 1.6e-14 54.0 0.0 1.6e-14 54.0 0.0 3.4 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase YhfH PF14149.1 EGG03335.1 - 0.18 11.6 0.8 0.43 10.4 0.5 1.6 1 0 0 1 1 1 0 YhfH-like protein Baculo_PEP_C PF04513.7 EGG03335.1 - 0.26 11.1 5.2 0.14 11.9 0.5 2.4 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAD_binding_8 PF08022.7 EGG03336.1 - 1.3e-12 47.5 0.0 3.9e-12 45.9 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EGG03336.1 - 5e-11 42.7 0.2 1.3e-08 34.8 0.1 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EGG03336.1 - 0.3 11.1 8.1 11 6.1 5.6 2.6 1 1 0 1 1 1 0 Ferric reductase like transmembrane component GST_C PF00043.20 EGG03337.1 - 6.7e-14 51.6 0.1 1.2e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGG03337.1 - 1.6e-13 50.6 0.0 3.6e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGG03337.1 - 4e-11 42.7 0.0 8e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGG03337.1 - 1.7e-10 40.9 0.0 3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGG03337.1 - 2e-06 27.6 0.1 9.4e-06 25.4 0.0 2.1 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGG03337.1 - 2.8e-06 27.7 0.1 5.3e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EGG03337.1 - 0.0028 18.0 0.1 0.0085 16.4 0.0 1.8 2 0 0 2 2 2 1 MetRS-N binding domain DUF4470 PF14737.1 EGG03340.1 - 6.9e-12 44.9 0.0 1.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EGG03340.1 - 5.2e-11 42.0 0.7 1.3e-10 40.7 0.5 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EGG03340.1 - 0.0012 18.6 0.4 0.34 10.9 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG03340.1 - 0.0013 18.6 0.0 0.0067 16.3 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGG03340.1 - 0.0085 15.6 0.8 0.55 9.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 EGG03341.1 - 4e-50 170.7 0.0 1.8e-49 168.6 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGG03341.1 - 5.1e-05 22.5 0.0 7.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EGG03341.1 - 0.0011 17.6 0.0 0.0023 16.5 0.0 1.5 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.15 EGG03341.1 - 0.11 10.7 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Arf PF00025.16 EGG03343.1 - 3.5e-79 264.0 0.1 4e-79 263.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGG03343.1 - 3e-14 52.6 0.0 3.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGG03343.1 - 4.1e-13 49.0 0.0 4.4e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EGG03343.1 - 3.8e-12 45.6 0.9 3.7e-09 35.7 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGG03343.1 - 3.3e-11 42.7 0.0 3.8e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGG03343.1 - 2.2e-09 37.8 0.0 3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGG03343.1 - 5.1e-06 26.4 0.0 6.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGG03343.1 - 0.0061 16.0 0.1 0.035 13.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EGG03343.1 - 0.0078 15.3 0.3 0.015 14.3 0.2 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EGG03343.1 - 0.038 13.8 0.3 0.13 12.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EGG03343.1 - 0.14 11.6 0.3 2.4 7.6 0.1 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3952 PF13130.1 EGG03344.1 - 0.11 12.5 0.3 0.2 11.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) ADH_zinc_N PF00107.21 EGG03345.1 - 5.7e-25 87.3 0.0 9.7e-25 86.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGG03345.1 - 3.2e-16 60.3 0.0 4.8e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EGG03345.1 - 0.0033 17.9 0.0 0.0071 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EGG03345.1 - 0.0092 15.7 0.0 0.041 13.6 0.0 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 EGG03345.1 - 0.059 13.3 0.1 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal TFIID_20kDa PF03847.8 EGG03346.1 - 1.9e-32 111.3 1.4 2.6e-32 110.9 1.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 EGG03346.1 - 0.00062 19.8 0.1 0.00099 19.1 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGG03346.1 - 0.0007 19.5 0.1 0.0013 18.7 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EGG03346.1 - 0.12 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF2547 PF10818.3 EGG03347.1 - 0.093 13.3 0.1 14 6.4 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) MxiH PF09392.5 EGG03349.1 - 0.21 12.1 3.2 0.44 11.1 2.2 1.6 1 1 0 1 1 1 0 Type III secretion needle MxiH like Pectinesterase PF01095.14 EGG03350.1 - 7.1e-24 83.8 0.4 1.2e-23 83.1 0.3 1.3 1 0 0 1 1 1 1 Pectinesterase Pectinesterase PF01095.14 EGG03351.1 - 3.6e-28 97.9 1.2 4.5e-28 97.6 0.8 1.1 1 0 0 1 1 1 1 Pectinesterase Adeno_E1B_55K PF01696.12 EGG03351.1 - 0.078 11.4 0.1 0.1 11.0 0.1 1.1 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen NOT2_3_5 PF04153.13 EGG03352.1 - 1.6e-34 118.6 2.8 1.6e-34 118.6 1.9 1.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF4106 PF13388.1 EGG03352.1 - 3.6 6.4 13.2 4.9 6.0 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DS PF01916.12 EGG03354.1 - 4.9e-14 52.1 0.1 8.8e-13 48.0 0.0 1.9 1 1 1 2 2 2 2 Deoxyhypusine synthase FAR1 PF03101.10 EGG03356.1 - 8e-05 23.0 1.0 0.00018 21.9 0.7 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EGG03356.1 - 0.0061 16.7 0.1 0.021 15.0 0.1 1.9 1 0 0 1 1 1 1 Transcription factor AFT PCEMA1 PF07418.6 EGG03357.1 - 0.0012 18.3 2.8 0.0019 17.6 1.9 1.3 1 0 0 1 1 1 1 Acidic phosphoprotein precursor PCEMA1 CwfJ_C_1 PF04677.10 EGG03357.1 - 0.019 14.5 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 IncA PF04156.9 EGG03357.1 - 0.036 13.6 2.6 0.09 12.3 1.8 1.7 1 0 0 1 1 1 0 IncA protein DSS1_SEM1 PF05160.8 EGG03357.1 - 7 6.5 10.8 0.1 12.3 0.6 2.7 2 0 0 2 2 2 0 DSS1/SEM1 family Cu-oxidase_3 PF07732.10 EGG03358.1 - 1.2e-32 112.0 0.0 3.2e-31 107.4 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EGG03358.1 - 5.9e-26 91.2 0.0 2.9e-24 85.7 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG03358.1 - 1e-22 80.1 5.1 7.9e-09 35.1 0.7 4.4 4 1 0 4 4 4 3 Multicopper oxidase DUF648 PF04890.8 EGG03360.1 - 0.96 8.5 5.4 0.48 9.5 2.2 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF648) Alb1 PF09135.6 EGG03360.1 - 1.3 9.6 6.3 0.66 10.6 0.8 2.2 2 0 0 2 2 2 0 Alb1 Nucleos_tra2_C PF07662.8 EGG03362.1 - 4.5e-59 199.4 0.8 4.5e-59 199.4 0.5 2.5 3 0 0 3 3 3 2 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EGG03362.1 - 2.2e-16 59.9 5.0 2.2e-16 59.9 3.5 3.6 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus PALP PF00291.20 EGG03363.1 - 9.1e-57 192.6 0.1 1e-56 192.4 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ox_reductase_C PF08635.5 EGG03365.1 - 2.7e-56 188.9 0.0 4.1e-56 188.3 0.0 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EGG03365.1 - 1.2e-20 74.1 0.0 2e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGG03365.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DUF4316 PF14195.1 EGG03366.1 - 0.88 9.6 3.8 2.3 8.3 2.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4316) SET PF00856.23 EGG03367.1 - 1.9e-12 47.7 0.0 1.8e-11 44.6 0.0 2.5 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 EGG03367.1 - 4.1e-12 46.1 0.7 8.7e-12 45.0 0.5 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding R3H PF01424.17 EGG03368.1 - 1e-10 41.1 0.0 2.6e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EGG03368.1 - 1.3e-09 37.6 0.3 2.9e-09 36.5 0.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGG03368.1 - 0.018 14.8 0.4 0.066 13.0 0.3 2.0 1 0 0 1 1 1 0 DExH-box splicing factor binding site Alpha_kinase PF02816.13 EGG03370.1 - 1.3e-09 38.0 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family COesterase PF00135.23 EGG03371.1 - 5.6e-90 302.5 0.0 1.3e-89 301.3 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family DUF3865 PF12981.2 EGG03372.1 - 0.02 14.6 0.6 0.14 11.9 0.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3865) PAP1 PF08601.5 EGG03372.1 - 0.046 13.3 26.8 7 6.2 18.6 2.9 1 1 0 1 1 1 0 Transcription factor PAP1 SOBP PF15279.1 EGG03372.1 - 2.5 8.4 14.9 0.35 11.2 5.0 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Clat_adaptor_s PF01217.15 EGG03373.1 - 5.3e-05 22.9 0.0 5.6e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1682 PF07946.9 EGG03374.1 - 8.9e-35 120.0 0.2 1e-34 119.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) ChuX_HutX PF06228.8 EGG03375.1 - 0.1 11.9 0.0 1.8 7.9 0.0 2.1 1 1 1 2 2 2 0 Haem utilisation ChuX/HutX Me-amine-dh_H PF06433.6 EGG03376.1 - 0.03 12.9 0.0 0.06 11.9 0.0 1.4 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) DUF874 PF05917.6 EGG03377.1 - 0.085 11.7 5.5 0.17 10.7 3.8 1.5 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Mating_C PF12737.2 EGG03380.1 - 0.016 14.1 6.3 0.025 13.4 4.4 1.3 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 FAM104 PF15434.1 EGG03380.1 - 0.087 13.0 1.9 0.61 10.3 1.6 2.1 2 0 0 2 2 2 0 Family 104 HMG_box PF00505.14 EGG03381.1 - 0.017 15.3 0.0 0.57 10.4 0.0 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box DPBB_1 PF03330.13 EGG03383.1 - 0.0044 17.0 0.2 0.02 14.8 0.0 2.1 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DPBB_1 PF03330.13 EGG03384.1 - 4.6e-06 26.5 0.2 0.00043 20.2 0.0 2.6 2 0 0 2 2 2 2 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Porin_O_P PF07396.6 EGG03389.1 - 0.016 14.1 0.1 0.019 13.8 0.1 1.1 1 0 0 1 1 1 0 Phosphate-selective porin O and P DUF3581 PF12119.3 EGG03390.1 - 0.2 10.8 1.3 0.31 10.2 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3581) AAA_23 PF13476.1 EGG03390.1 - 2.4 8.4 7.2 3.2 8.0 5.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4559 PF15112.1 EGG03390.1 - 3.8 6.5 9.6 4.9 6.2 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) zf-UBR PF02207.15 EGG03391.1 - 0.026 14.2 9.2 0.03 14.0 6.4 1.1 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) TPR_11 PF13414.1 EGG03392.1 - 2.3e-16 59.1 0.3 1.7e-09 37.2 0.1 4.0 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 EGG03392.1 - 6.4e-13 47.7 0.1 0.017 14.7 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGG03392.1 - 1.3e-10 40.3 5.2 0.016 15.0 0.0 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGG03392.1 - 4.6e-07 30.3 0.5 0.0028 18.2 0.0 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG03392.1 - 5.5e-07 29.4 2.8 0.0099 15.7 0.1 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGG03392.1 - 7.9e-07 28.8 0.2 0.00039 20.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGG03392.1 - 7.9e-07 28.4 0.0 0.93 9.4 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGG03392.1 - 1.6e-06 28.2 0.4 0.0058 17.1 0.2 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGG03392.1 - 0.0099 16.1 0.0 0.32 11.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG03392.1 - 0.012 15.3 0.2 65 3.6 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Homez PF11569.3 EGG03394.1 - 0.014 14.4 0.1 0.023 13.7 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Uds1 PF15456.1 EGG03396.1 - 0.017 15.1 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Up-regulated During Septation SAP PF02037.22 EGG03397.1 - 0.0004 19.8 0.8 0.00073 18.9 0.5 1.4 1 0 0 1 1 1 1 SAP domain SAP PF02037.22 EGG03398.1 - 0.027 13.9 0.4 0.23 11.0 0.0 2.5 2 0 0 2 2 2 0 SAP domain Vac14_Fig4_bd PF11916.3 EGG03398.1 - 0.038 13.1 0.5 7.4 5.6 0.1 2.3 2 0 0 2 2 2 0 Vacuolar protein 14 C-terminal Fig4p binding SAP PF02037.22 EGG03399.1 - 0.0027 17.1 0.5 0.0054 16.2 0.3 1.4 1 0 0 1 1 1 1 SAP domain BMF PF15185.1 EGG03399.1 - 0.0077 15.5 0.2 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 Bcl-2-modifying factor, apoptosis RTX_C PF08339.5 EGG03404.1 - 2.9 7.5 8.9 0.44 10.2 2.6 1.9 1 1 1 2 2 2 0 RTX C-terminal domain Peptidase_S28 PF05577.7 EGG03405.1 - 2.2e-56 191.2 0.0 1.1e-55 188.9 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Clat_adaptor_s PF01217.15 EGG03410.1 - 6.1e-47 158.9 2.7 7.2e-47 158.6 1.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain BTB PF00651.26 EGG03412.1 - 1.4e-08 34.6 0.8 0.00081 19.3 0.0 3.1 3 0 0 3 3 3 2 BTB/POZ domain Nop14 PF04147.7 EGG03412.1 - 0.14 10.0 10.5 0.21 9.4 7.3 1.2 1 0 0 1 1 1 0 Nop14-like family RRM_6 PF14259.1 EGG03413.1 - 0.041 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGG03413.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBN2_3 PF14244.1 EGG03414.1 - 1.9e-05 24.2 1.7 1.9e-05 24.2 1.2 1.8 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG03414.1 - 0.0023 17.4 0.5 0.0068 15.9 0.4 1.8 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Mad3_BUB1_I PF08311.7 EGG03414.1 - 0.03 14.1 1.1 0.042 13.6 0.2 1.7 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 Polysacc_lyase PF14099.1 EGG03415.1 - 3.1e-07 30.3 0.1 5.6e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide lyase dCMP_cyt_deam_1 PF00383.17 EGG03416.1 - 3.9e-10 39.2 0.0 5.1e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EGG03416.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 1 0 1 1 1 0 APOBEC-like N-terminal domain DUF410 PF04190.8 EGG03417.1 - 5.6e-31 108.0 0.0 1.5e-23 83.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF410) TPR_8 PF13181.1 EGG03417.1 - 0.048 13.4 0.1 0.4 10.5 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat DicB PF05358.6 EGG03417.1 - 0.094 12.2 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 DicB protein DUF1391 PF07151.7 EGG03419.1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) Ribosomal_L41 PF05162.8 EGG03419.1 - 0.36 10.5 6.3 0.51 10.0 4.3 1.3 1 0 0 1 1 1 0 Ribosomal protein L41 AA_permease PF00324.16 EGG03420.1 - 1.5e-121 406.0 35.8 1.8e-121 405.7 24.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGG03420.1 - 1.6e-35 122.5 37.5 1.9e-35 122.2 26.0 1.1 1 0 0 1 1 1 1 Amino acid permease Not1 PF04054.10 EGG03421.1 - 1.3e-84 284.3 0.1 3.3e-84 282.9 0.0 1.7 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EGG03421.1 - 4.2e-44 149.7 0.4 1.5e-43 147.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Glyco_hydro_47 PF01532.15 EGG03424.1 - 0.00045 19.0 0.0 0.00066 18.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2222 PF09984.4 EGG03424.1 - 0.025 14.0 1.0 0.11 11.8 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) Glyco_hydro_47 PF01532.15 EGG03425.1 - 6e-120 400.9 0.0 6.8e-120 400.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Hid1 PF12722.2 EGG03426.1 - 4.7e-101 338.9 6.1 3.5e-77 259.9 0.0 4.5 2 2 3 5 5 5 4 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EGG03426.1 - 3.1e-40 138.0 0.0 1.9e-39 135.3 0.0 2.0 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein SLD3 PF08639.5 EGG03427.1 - 1.1e-09 37.5 14.2 1.8e-09 36.7 9.9 1.3 1 0 0 1 1 1 1 DNA replication regulator SLD3 Abhydrolase_5 PF12695.2 EGG03430.1 - 2.2e-10 40.4 0.0 3.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG03430.1 - 2.9e-09 37.1 0.1 9.9e-09 35.4 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EGG03430.1 - 0.0038 16.8 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF1749 PF08538.5 EGG03430.1 - 0.049 12.5 0.0 3.4 6.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 EGG03430.1 - 0.11 12.0 0.0 5.8 6.3 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold Peptidase_C15 PF01470.12 EGG03431.1 - 5.6e-13 49.1 0.0 1.1e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase DUF2594 PF10769.4 EGG03431.1 - 0.1 12.7 0.1 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) RRM_1 PF00076.17 EGG03434.1 - 1.1e-20 73.0 0.1 6e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG03434.1 - 2.4e-11 43.3 0.0 0.00025 20.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG03434.1 - 8.1e-11 41.7 0.0 0.00016 21.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGG03434.1 - 0.012 15.3 0.0 4.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 MARVEL PF01284.18 EGG03435.1 - 0.14 11.9 11.8 0.18 11.5 7.6 1.6 1 1 1 2 2 2 0 Membrane-associating domain NAM PF02365.10 EGG03436.1 - 1.3 9.2 4.8 31 4.7 0.1 2.8 3 0 0 3 3 3 0 No apical meristem (NAM) protein ABC1 PF03109.11 EGG03438.1 - 3.5e-24 85.0 0.0 2.7e-15 56.3 0.0 2.7 3 0 0 3 3 3 2 ABC1 family Homeobox PF00046.24 EGG03439.1 - 1.9e-09 36.9 0.2 4.4e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EGG03439.1 - 1.3e-06 27.9 0.9 4e-06 26.4 0.6 1.9 1 0 0 1 1 1 1 Homeobox KN domain DUF1759 PF03564.10 EGG03441.1 - 0.0027 17.5 0.1 0.0078 16.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Homeobox PF00046.24 EGG03442.1 - 0.0013 18.3 0.0 0.0044 16.6 0.0 1.8 1 0 0 1 1 1 1 Homeobox domain LacI PF00356.16 EGG03443.1 - 0.056 13.0 0.0 0.18 11.4 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family PRANC PF09372.5 EGG03445.1 - 0.21 11.5 2.6 0.85 9.6 0.1 3.0 3 0 0 3 3 3 0 PRANC domain DUF659 PF04937.10 EGG03446.1 - 0.027 13.9 0.2 0.056 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Mg_trans_NIPA PF05653.9 EGG03447.1 - 9.7e-22 77.2 17.4 1.6e-14 53.5 4.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA DUF2421 PF10334.4 EGG03448.1 - 2.7e-08 33.6 1.7 8.1e-05 22.3 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) DUF2422 PF10337.4 EGG03448.1 - 0.00022 20.1 3.4 0.00022 20.1 2.4 3.9 4 1 1 5 5 5 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EGG03448.1 - 0.00026 20.8 25.8 0.0072 16.2 3.1 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like UIM PF02809.15 EGG03448.1 - 0.35 10.5 1.8 25 4.8 0.2 3.0 2 0 0 2 2 2 0 Ubiquitin interaction motif Stc1 PF12898.2 EGG03449.1 - 3e-10 39.9 13.1 5e-07 29.6 6.3 2.5 1 1 1 2 2 2 2 Stc1 domain zf-DHHC PF01529.15 EGG03449.1 - 0.006 15.9 4.2 0.006 15.9 2.9 2.8 2 1 1 3 3 3 1 DHHC palmitoyltransferase DUF4428 PF14471.1 EGG03449.1 - 0.017 14.8 0.2 0.017 14.8 0.1 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4428) DUF912 PF06024.7 EGG03449.1 - 0.099 12.7 0.8 0.48 10.5 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Whib PF02467.11 EGG03449.1 - 0.23 11.7 6.6 0.78 10.0 0.0 2.9 3 0 0 3 3 3 0 Transcription factor WhiB C1_1 PF00130.17 EGG03449.1 - 0.33 10.7 7.6 2.7 7.7 1.0 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.7 EGG03449.1 - 0.35 10.6 9.7 0.31 10.8 1.4 2.9 2 1 1 3 3 3 0 zinc-ribbons FYVE PF01363.16 EGG03449.1 - 2.7 7.9 8.8 38 4.2 6.1 2.4 1 1 0 1 1 1 0 FYVE zinc finger A2L_zn_ribbon PF08792.5 EGG03449.1 - 3.3 7.2 11.7 0.39 10.2 0.2 3.5 4 0 0 4 4 4 0 A2L zinc ribbon domain zf-B_box PF00643.19 EGG03449.1 - 4.3 7.3 10.7 22 5.0 0.1 3.5 3 0 0 3 3 3 0 B-box zinc finger DUF1660 PF07874.6 EGG03449.1 - 7.6 6.8 17.8 0.31 11.3 1.3 3.6 1 1 2 3 3 3 0 Prophage protein (DUF1660) GGDN PF05165.7 EGG03450.1 - 0.17 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 GGDN family NRDE-2 PF08424.5 EGG03451.1 - 1.7e-53 181.6 19.5 4.1e-53 180.3 0.0 4.6 4 1 0 4 4 4 3 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EGG03451.1 - 0.00013 22.3 1.0 69 4.4 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat zf-CCHC_6 PF15288.1 EGG03453.1 - 0.015 14.9 1.2 0.015 14.9 0.8 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EGG03453.1 - 0.084 12.8 3.5 0.17 11.8 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle SOBP PF15279.1 EGG03453.1 - 0.29 11.4 3.3 0.38 11.0 2.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Alpha_kinase PF02816.13 EGG03455.1 - 3.4e-06 26.8 0.6 4.6e-06 26.4 0.4 1.2 1 0 0 1 1 1 1 Alpha-kinase family Sod_Cu PF00080.15 EGG03456.1 - 1.8e-16 60.5 0.7 3e-16 59.8 0.5 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Sod_Cu PF00080.15 EGG03458.1 - 6.6e-17 61.9 0.1 8.9e-17 61.5 0.1 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pyrid_oxidase_2 PF13883.1 EGG03459.1 - 2.1e-22 79.6 0.0 2.6e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3392 PF11872.3 EGG03460.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3392) FERM_N PF09379.5 EGG03462.1 - 0.024 14.6 0.1 1.7 8.7 0.1 2.9 2 1 0 2 2 2 0 FERM N-terminal domain IL22 PF14565.1 EGG03463.1 - 0.012 15.6 1.9 0.027 14.5 0.1 2.2 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor DUF663 PF04950.7 EGG03464.1 - 1.3e-85 286.9 0.0 3e-85 285.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EGG03464.1 - 1.8e-16 59.4 0.0 4.5e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EGG03464.1 - 1.3e-07 31.2 0.0 2e-05 24.1 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGG03464.1 - 1.6e-05 25.0 0.0 3.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG03464.1 - 4.1e-05 24.3 0.8 0.00058 20.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGG03464.1 - 7.2e-05 22.8 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EGG03464.1 - 0.00028 21.0 0.0 0.00055 20.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGG03464.1 - 0.00078 19.7 0.4 0.021 15.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGG03464.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EGG03464.1 - 0.0013 18.4 0.1 0.0033 17.1 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EGG03464.1 - 0.0023 18.4 0.0 0.0073 16.7 0.0 1.9 2 0 0 2 2 1 1 Miro-like protein AAA_19 PF13245.1 EGG03464.1 - 0.0026 17.4 0.4 0.0065 16.1 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EGG03464.1 - 0.0035 17.3 1.2 0.0047 16.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 EGG03464.1 - 0.0049 17.1 0.3 0.017 15.4 0.0 2.0 2 0 0 2 2 1 1 ABC transporter NACHT PF05729.7 EGG03464.1 - 0.0057 16.3 0.0 0.014 15.0 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 EGG03464.1 - 0.0088 15.4 0.2 0.06 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EGG03464.1 - 0.014 15.0 0.8 0.025 14.1 0.1 1.8 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.17 EGG03464.1 - 0.018 13.8 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 EGG03464.1 - 0.019 14.8 0.0 0.019 14.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EGG03464.1 - 0.022 14.4 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.14 EGG03464.1 - 0.03 13.7 0.1 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EGG03464.1 - 0.058 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EGG03464.1 - 0.06 12.8 0.0 0.45 10.0 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 EGG03464.1 - 0.06 13.2 0.1 0.24 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGG03464.1 - 0.089 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EGG03464.1 - 0.11 12.2 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pkinase PF00069.20 EGG03465.1 - 1.4e-38 132.5 0.0 1.7e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG03465.1 - 1.5e-15 56.9 0.0 1.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG03465.1 - 4.7e-05 23.2 0.1 0.0026 17.5 0.0 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EGG03465.1 - 0.021 13.6 0.1 0.031 13.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EGG03465.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGG03465.1 - 0.13 11.8 0.1 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SAD_SRA PF02182.12 EGG03470.1 - 2.5e-46 156.8 0.0 4.9e-46 155.8 0.0 1.5 1 0 0 1 1 1 1 SAD/SRA domain SAD_SRA PF02182.12 EGG03472.1 - 3.4e-46 156.3 0.0 7.8e-46 155.1 0.0 1.6 1 0 0 1 1 1 1 SAD/SRA domain eIF3g PF12353.3 EGG03474.1 - 0.11 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Pkinase PF00069.20 EGG03476.1 - 1.3e-59 201.4 0.1 1.5e-59 201.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG03476.1 - 2.5e-35 121.8 0.0 2.8e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG03476.1 - 6.5e-05 22.7 0.1 0.00029 20.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGG03476.1 - 0.00023 20.2 0.0 0.0009 18.2 0.0 1.8 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EGG03476.1 - 0.00089 18.6 0.8 0.0027 17.0 0.6 1.7 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 EGG03476.1 - 0.003 16.6 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CDGSH PF09360.5 EGG03477.1 - 0.024 14.4 1.3 0.061 13.1 0.9 1.7 1 0 0 1 1 1 0 Iron-binding zinc finger CDGSH type Agro_virD5 PF04730.7 EGG03478.1 - 0.081 10.9 0.0 0.081 10.9 0.0 1.0 1 0 0 1 1 1 0 Agrobacterium VirD5 protein Glyco_transf_90 PF05686.7 EGG03480.1 - 7.6e-15 54.4 4.1 5.9e-14 51.5 2.9 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 Syntaphilin PF15290.1 EGG03480.1 - 0.14 11.6 0.4 0.25 10.7 0.3 1.3 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp IF-2B PF01008.12 EGG03481.1 - 8.9e-55 185.6 0.1 1.1e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family SLX9 PF15341.1 EGG03482.1 - 1.1e-17 64.5 7.6 2e-17 63.7 5.3 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF1840 PF08895.6 EGG03482.1 - 0.048 13.6 0.4 0.085 12.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF964 PF06133.6 EGG03482.1 - 0.074 13.0 0.4 0.2 11.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF964) Allexi_40kDa PF05549.6 EGG03482.1 - 0.087 12.0 4.3 0.099 11.9 2.7 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein T5orf172 PF10544.4 EGG03482.1 - 0.31 11.4 5.2 0.23 11.8 1.0 2.4 1 1 1 2 2 2 0 T5orf172 domain Erp_C PF06780.6 EGG03482.1 - 0.88 9.4 5.0 0.37 10.6 1.3 1.9 1 1 1 2 2 2 0 Erp protein C-terminus Erf4 PF10256.4 EGG03483.1 - 6.6e-19 67.9 0.0 1.2e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family CDK5_activator PF03261.10 EGG03483.1 - 0.17 11.1 4.4 0.23 10.7 3.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF605 PF04652.11 EGG03483.1 - 4.9 6.4 21.6 6 6.1 15.0 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EGG03484.1 - 0.026 12.7 4.7 0.036 12.3 3.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_transf_8 PF01501.15 EGG03486.1 - 1.1e-38 133.0 0.0 1.8e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EGG03486.1 - 0.05 12.9 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative PepSY_TM_1 PF13172.1 EGG03487.1 - 0.0011 18.6 0.3 0.0016 18.1 0.2 1.2 1 0 0 1 1 1 1 PepSY-associated TM helix DASH_Dad2 PF08654.5 EGG03488.1 - 5.7e-12 45.5 0.6 6.8e-12 45.3 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DUF1741 PF08427.5 EGG03489.1 - 5.6e-31 107.8 0.0 2.9e-29 102.2 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1741) Vel1p PF10339.4 EGG03491.1 - 0.022 13.9 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Yeast-specific zinc responsive Glucan_synthase PF02364.10 EGG03493.1 - 0.055 11.3 3.3 0.057 11.2 2.3 1.2 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Pyrid_oxidase_2 PF13883.1 EGG03494.1 - 2e-21 76.5 0.0 3.2e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SGT1 PF07093.6 EGG03494.1 - 0.00016 20.2 9.7 0.00022 19.7 6.7 1.3 1 0 0 1 1 1 1 SGT1 protein Pyridox_ox_2 PF12900.2 EGG03494.1 - 0.0029 17.4 0.1 0.02 14.7 0.0 2.3 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF883 PF05957.8 EGG03494.1 - 0.079 13.3 0.2 0.35 11.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HAUS6_N PF14661.1 EGG03494.1 - 0.87 8.8 5.6 2 7.7 3.9 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RP-C_C PF11800.3 EGG03494.1 - 1.4 8.5 6.8 2.9 7.5 4.7 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region AATF-Che1 PF13339.1 EGG03494.1 - 1.8 8.7 9.1 0.61 10.2 3.2 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Astro_capsid PF03115.9 EGG03494.1 - 8 4.5 11.8 11 4.0 8.2 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CAF-1_p150 PF11600.3 EGG03495.1 - 0.57 9.5 20.3 0.78 9.0 14.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Myb_DNA-binding PF00249.26 EGG03496.1 - 3.8 7.6 5.7 4.9 7.2 0.2 3.4 2 1 0 2 2 2 0 Myb-like DNA-binding domain Glycos_trans_3N PF02885.12 EGG03497.1 - 0.14 11.7 0.8 0.43 10.1 0.0 2.2 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain LRR_4 PF12799.2 EGG03498.1 - 0.31 10.7 5.1 7.7 6.2 0.2 3.7 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Pal1 PF08316.6 EGG03499.1 - 3e-06 27.7 3.0 7.6e-06 26.4 1.6 2.0 1 1 1 2 2 2 1 Pal1 cell morphology protein Ribosomal_S7e PF01251.13 EGG03500.1 - 7.5e-82 273.4 1.8 8.3e-82 273.2 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e GxGYxYP PF14323.1 EGG03502.1 - 0.1 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function Homeobox_KN PF05920.6 EGG03504.1 - 9.9e-09 34.7 0.0 2.2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EGG03504.1 - 5e-06 26.0 0.3 1.6e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 EGG03504.1 - 0.021 13.8 3.8 0.07 12.1 0.1 2.7 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez DUF4167 PF13763.1 EGG03507.1 - 0.0041 17.1 0.0 0.22 11.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4167) Pkinase PF00069.20 EGG03511.1 - 4.3e-60 203.0 0.0 4.8e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG03511.1 - 5e-43 147.0 0.0 5.5e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EGG03511.1 - 2.2e-05 23.8 0.0 6.1e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EGG03511.1 - 3.1e-05 23.1 0.0 4.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGG03511.1 - 0.00082 18.4 0.1 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGG03511.1 - 0.0012 18.1 0.2 0.0029 17.0 0.1 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EGG03511.1 - 0.0086 15.8 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Nramp PF01566.13 EGG03512.1 - 3.4e-56 190.5 14.7 4.2e-56 190.2 10.2 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF4448 PF14610.1 EGG03521.1 - 0.00095 18.7 0.2 0.0027 17.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EGG03521.1 - 0.014 15.1 0.1 0.014 15.1 0.1 2.9 2 2 1 3 3 3 0 TMEM154 protein family G-patch_2 PF12656.2 EGG03523.1 - 3.5e-23 81.2 2.2 7.6e-23 80.1 0.0 2.8 2 1 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 EGG03523.1 - 0.016 14.9 1.4 0.048 13.4 1.0 1.9 1 1 0 1 1 1 0 G-patch domain Nudix_N_2 PF14803.1 EGG03524.1 - 0.087 12.5 1.4 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 Nudix N-terminal zf-Mss51 PF13824.1 EGG03524.1 - 2.2 8.2 9.0 0.16 11.8 2.7 1.8 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Bestrophin PF01062.16 EGG03525.1 - 7.5e-37 126.8 0.8 1.1e-28 100.0 0.0 2.7 2 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel SYF2 PF08231.7 EGG03526.1 - 4.6e-44 150.2 17.5 4.6e-44 150.2 12.2 1.5 2 0 0 2 2 2 1 SYF2 splicing factor YusW PF14039.1 EGG03526.1 - 0.014 15.7 0.4 0.043 14.0 0.1 2.0 1 1 1 2 2 2 0 YusW-like protein Poxvirus PF06227.7 EGG03526.1 - 0.033 13.7 0.4 0.033 13.7 0.3 1.7 2 0 0 2 2 2 0 dsDNA Poxvirus PINIT PF14324.1 EGG03529.1 - 4.3e-26 91.7 0.3 9e-26 90.6 0.2 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EGG03529.1 - 2.2e-17 62.2 0.9 2.2e-17 62.2 0.6 2.0 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EGG03529.1 - 1.4e-05 24.4 0.2 1.4e-05 24.4 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 EGG03529.1 - 0.008 15.6 0.0 0.41 10.2 0.0 2.4 2 0 0 2 2 2 1 SAP domain HOOK PF05622.7 EGG03534.1 - 2.5e-40 138.0 87.3 1.9e-39 135.1 45.6 2.6 1 1 1 2 2 2 2 HOOK protein Laminin_II PF06009.7 EGG03534.1 - 0.0015 18.3 4.4 0.0015 18.3 3.0 6.5 5 2 3 8 8 8 2 Laminin Domain II HMG_box_5 PF14887.1 EGG03537.1 - 6.7e-05 22.6 10.1 4.7 7.0 0.1 4.3 4 0 0 4 4 4 4 HMG (high mobility group) box 5 STOP PF05217.7 EGG03537.1 - 0.0013 18.5 0.5 23 4.6 0.0 3.7 4 0 0 4 4 4 0 STOP protein MAPKK1_Int PF08923.5 EGG03537.1 - 0.0024 17.5 0.3 61 3.2 0.0 4.0 4 0 0 4 4 4 0 Mitogen-activated protein kinase kinase 1 interacting Lac_bphage_repr PF06543.7 EGG03537.1 - 0.0092 15.4 1.5 27 4.3 0.0 4.1 4 0 0 4 4 4 0 Lactococcus bacteriophage repressor UPF0257 PF06788.8 EGG03537.1 - 0.073 12.2 2.2 88 2.2 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0257) 3-alpha PF03475.9 EGG03537.1 - 0.14 11.8 8.0 31 4.4 0.1 4.3 4 0 0 4 4 4 0 3-alpha domain LTXXQ PF07813.7 EGG03537.1 - 0.15 12.5 7.7 20 5.6 0.1 3.8 4 0 0 4 4 4 0 LTXXQ motif family protein Flagellin_N PF00669.15 EGG03537.1 - 0.21 11.4 3.6 34 4.2 0.1 3.8 3 1 0 4 4 4 0 Bacterial flagellin N-terminal helical region CagY_M PF07337.6 EGG03537.1 - 8.9 5.8 8.8 1.3e+02 2.1 0.1 4.5 4 0 0 4 4 4 0 DC-EC Repeat Gemini_C4 PF01492.12 EGG03539.1 - 0.17 11.6 1.5 0.24 11.1 1.0 1.3 1 0 0 1 1 1 0 Geminivirus C4 protein Hormone_5 PF00184.12 EGG03541.1 - 4.5 7.8 9.8 25 5.4 0.1 2.3 2 0 0 2 2 2 0 Neurohypophysial hormones, C-terminal Domain Dynamin_N PF00350.18 EGG03542.1 - 8.7e-42 142.7 0.0 2.4e-41 141.3 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EGG03542.1 - 9.9e-12 44.2 0.3 5.5e-10 38.4 0.1 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EGG03542.1 - 0.00041 20.2 0.0 0.0013 18.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGG03542.1 - 0.0036 17.7 0.0 0.0098 16.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 EGG03542.1 - 0.046 13.6 2.1 0.2 11.6 0.0 2.8 3 1 0 3 3 3 0 AAA domain Pyr_redox_3 PF13738.1 EGG03543.1 - 7.3e-05 22.9 0.0 0.018 15.0 0.0 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGG03543.1 - 0.00038 20.2 0.0 0.00082 19.1 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGG03543.1 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGG03543.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Gpi16 PF04113.9 EGG03544.1 - 6.4e-122 407.4 0.0 6e-121 404.2 0.0 2.2 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LRR_4 PF12799.2 EGG03545.1 - 0.2 11.3 8.6 28 4.4 0.0 4.5 2 2 3 5 5 5 0 Leucine Rich repeats (2 copies) Gly_transf_sug PF04488.10 EGG03546.1 - 2.1e-19 69.8 0.0 5e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EGG03546.1 - 0.014 13.9 1.9 0.092 11.2 0.2 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EGG03546.1 - 0.13 11.3 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein BCDHK_Adom3 PF10436.4 EGG03547.1 - 4.5e-38 130.3 1.6 6.3e-38 129.8 1.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGG03547.1 - 2.5e-05 23.9 0.0 0.00017 21.2 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dicty_REP PF05086.7 EGG03548.1 - 0.0023 15.7 3.9 0.0028 15.5 2.7 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Not1 PF04054.10 EGG03548.1 - 0.15 10.9 0.5 0.2 10.5 0.3 1.1 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 CobT PF06213.7 EGG03548.1 - 1.6 7.7 16.3 0.24 10.4 8.1 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Keratin_B2 PF01500.12 EGG03549.1 - 0.17 11.6 4.8 0.063 13.0 0.8 2.3 2 1 0 2 2 2 0 Keratin, high sulfur B2 protein DUF946 PF06101.6 EGG03552.1 - 6.6e-05 21.0 0.5 0.05 11.5 0.0 2.5 3 0 0 3 3 3 2 Plant protein of unknown function (DUF946) CMV_1a PF12467.3 EGG03554.1 - 4.1 7.7 9.4 4.3 7.6 6.0 1.4 1 1 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF1758 PF05585.7 EGG03555.1 - 0.024 14.2 0.6 0.044 13.3 0.1 1.6 2 0 0 2 2 2 0 Putative peptidase (DUF1758) zf-3CxxC PF13695.1 EGG03555.1 - 0.09 13.0 0.2 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Zinc-binding domain DUF1771 PF08590.5 EGG03558.1 - 0.1 12.6 0.6 0.22 11.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) API5 PF05918.6 EGG03559.1 - 2 6.8 6.8 2.7 6.3 4.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Helitron_like_N PF14214.1 EGG03560.1 - 0.018 14.7 0.3 0.027 14.2 0.2 1.3 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus AMPKBI PF04739.10 EGG03560.1 - 1.4 8.8 9.6 0.5 10.2 0.8 2.2 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interation domain SNF2_N PF00176.18 EGG03562.1 - 8e-56 189.0 2.0 1e-55 188.6 0.5 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGG03562.1 - 1.7e-10 40.6 0.1 4.2e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGG03562.1 - 0.00014 21.3 0.0 0.00071 19.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 EGG03562.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpb1_5 PF04998.12 EGG03566.1 - 8.7e-91 304.0 0.0 2.1e-90 302.7 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGG03566.1 - 1.1e-59 201.1 0.1 3.5e-59 199.4 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGG03566.1 - 1.7e-35 122.0 0.0 5.9e-35 120.3 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EGG03566.1 - 1.6e-30 106.5 9.7 4.4e-25 88.6 0.2 3.9 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EGG03566.1 - 1.5e-21 76.1 0.8 3.9e-21 74.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 PQQ PF01011.16 EGG03566.1 - 0.17 11.4 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat F-box-like PF12937.2 EGG03567.1 - 7.8e-07 28.7 0.5 2.8e-06 26.9 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGG03567.1 - 0.00024 20.6 0.3 0.027 14.1 0.0 2.6 2 0 0 2 2 2 2 F-box domain NIPSNAP PF07978.8 EGG03568.1 - 2.2e-34 117.4 0.3 2.2e-25 88.5 0.1 2.2 2 0 0 2 2 2 2 NIPSNAP TFIIA PF03153.8 EGG03569.1 - 0.00019 21.4 8.7 0.00019 21.4 6.0 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Asp-B-Hydro_N PF05279.6 EGG03571.1 - 5.9 6.6 12.9 10 5.8 9.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Lipase_3 PF01764.20 EGG03572.1 - 9e-07 28.5 0.0 2.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGG03572.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DnaJ PF00226.26 EGG03573.1 - 1.6e-24 85.3 2.5 2.4e-24 84.8 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGG03573.1 - 3.1e-14 52.6 4.0 9.7e-11 41.4 0.9 3.7 2 1 0 2 2 2 2 DnaJ C terminal domain Ribosomal_L7Ae PF01248.21 EGG03574.1 - 5.8e-26 89.8 0.1 6.8e-26 89.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EGG03574.1 - 0.00017 21.4 0.1 0.0002 21.2 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EGG03574.1 - 0.041 13.6 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain Rxt3 PF08642.5 EGG03574.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.4 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 FlxA PF14282.1 EGG03574.1 - 0.22 11.5 4.9 0.41 10.6 1.0 2.1 2 0 0 2 2 2 0 FlxA-like protein Calreticulin PF00262.13 EGG03582.1 - 3.5e-160 532.6 12.4 4.6e-160 532.2 8.6 1.1 1 0 0 1 1 1 1 Calreticulin family Aldo_ket_red PF00248.16 EGG03583.1 - 7.2e-43 146.4 0.0 1e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family MSG PF02349.10 EGG03583.1 - 0.085 12.8 0.3 0.23 11.4 0.2 1.6 1 0 0 1 1 1 0 Major surface glycoprotein Sod_Cu PF00080.15 EGG03584.1 - 5.5e-09 36.2 0.3 1.8e-08 34.6 0.1 1.9 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Cyclin PF08613.6 EGG03587.1 - 1.9e-30 106.2 0.1 4.7e-30 104.9 0.1 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EGG03587.1 - 0.091 12.3 0.7 0.26 10.8 0.4 1.9 1 1 0 1 1 1 0 Cyclin, N-terminal domain ALAD PF00490.16 EGG03588.1 - 1.1e-119 399.1 0.0 1.2e-119 399.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Ebp2 PF05890.7 EGG03590.1 - 5.2e-42 144.0 17.7 7.4e-42 143.5 12.3 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Myc_N PF01056.13 EGG03590.1 - 0.33 10.0 6.9 0.55 9.3 4.8 1.4 1 0 0 1 1 1 0 Myc amino-terminal region TSGP1 PF07771.6 EGG03591.1 - 8.5 6.2 8.9 0.59 10.0 2.7 1.6 2 0 0 2 2 2 0 Tick salivary peptide group 1 CATSPERD PF15020.1 EGG03592.1 - 0.012 13.6 0.6 0.015 13.3 0.4 1.0 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta Invas_SpaK PF03519.9 EGG03592.1 - 0.089 12.6 1.2 0.45 10.3 0.2 2.6 2 1 1 3 3 3 0 Invasion protein B family ABC_tran_2 PF12848.2 EGG03592.1 - 0.13 12.1 0.4 0.27 11.0 0.3 1.5 1 0 0 1 1 1 0 ABC transporter CemA PF03040.9 EGG03592.1 - 1.3 8.5 4.4 1.5 8.4 3.0 1.1 1 0 0 1 1 1 0 CemA family zf-MYND PF01753.13 EGG03593.1 - 6.3e-09 35.5 14.4 6.3e-09 35.5 10.0 2.1 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 EGG03593.1 - 0.0039 17.0 5.7 0.01 15.6 3.9 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 RRM_5 PF13893.1 EGG03594.1 - 2.8e-08 33.4 0.0 5.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGG03594.1 - 2.2e-07 30.3 0.0 5.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG03594.1 - 0.00039 20.3 0.0 0.00077 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGG03594.1 - 0.0023 17.6 0.1 0.0062 16.2 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif CsgE PF10627.4 EGG03594.1 - 0.045 13.5 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Curli assembly protein CsgE Trypan_PARP PF05887.6 EGG03594.1 - 2.2 8.0 10.6 0.13 12.1 2.7 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Trehalase PF01204.13 EGG03595.1 - 3.3e-88 296.5 0.3 1.4e-74 251.5 0.0 2.4 2 1 0 2 2 2 2 Trehalase GDE_C PF06202.9 EGG03595.1 - 1.7e-05 23.7 0.1 0.0024 16.6 0.0 2.1 2 0 0 2 2 2 2 Amylo-alpha-1,6-glucosidase Ribosomal_L22e PF01776.12 EGG03596.1 - 5.3e-42 142.3 0.3 6.3e-42 142.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Pro_isomerase PF00160.16 EGG03600.1 - 6.4e-45 153.1 0.3 7.1e-45 152.9 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TEX13 PF15186.1 EGG03600.1 - 0.092 12.3 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Adaptin_N PF01602.15 EGG03601.1 - 1.9e-93 313.5 5.4 2.6e-93 313.1 3.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EGG03601.1 - 1e-64 216.0 0.1 2.9e-64 214.6 0.0 1.9 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EGG03601.1 - 5.4e-63 210.8 0.5 1.3e-62 209.6 0.3 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EGG03601.1 - 3.8e-11 43.1 0.6 0.01 16.1 0.0 4.4 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.2 EGG03601.1 - 4.5e-08 33.1 5.5 0.12 12.1 0.0 4.7 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EGG03601.1 - 8.1e-07 28.6 1.5 0.21 11.7 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EGG03601.1 - 0.0033 17.8 0.1 14 6.3 0.0 4.8 4 1 1 5 5 5 1 HEAT-like repeat Alpha_kinase PF02816.13 EGG03602.1 - 1.5e-07 31.2 0.0 2.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family DASH_Ask1 PF08655.5 EGG03603.1 - 9.6e-23 79.7 0.0 2.1e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 FAD_binding_4 PF01565.18 EGG03604.1 - 1.8e-28 98.7 1.6 3.7e-28 97.7 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGG03604.1 - 1.5e-14 53.5 0.9 2.9e-14 52.6 0.6 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EGG03604.1 - 0.013 14.6 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.18 EGG03606.1 - 8e-28 96.6 2.5 9.6e-28 96.3 1.7 1.1 1 0 0 1 1 1 1 FAD binding domain Cnd1_N PF12922.2 EGG03608.1 - 1.3e-40 138.8 0.9 1.3e-40 138.8 0.6 2.1 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term RPOL_N PF14700.1 EGG03608.1 - 0.073 12.3 0.7 0.11 11.6 0.1 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal Ipi1_N PF12333.3 EGG03608.1 - 0.078 12.9 1.6 0.16 11.9 0.3 2.1 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 EGG03609.1 - 2.6e-41 141.4 1.4 2.6e-41 141.4 1.0 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGG03609.1 - 0.013 15.8 0.0 0.25 11.6 0.0 3.1 4 0 0 4 4 4 0 HEAT repeats HEAT_EZ PF13513.1 EGG03609.1 - 0.031 14.7 0.0 11 6.6 0.1 3.8 2 2 2 4 4 4 0 HEAT-like repeat HEAT PF02985.17 EGG03609.1 - 0.034 14.2 0.0 11 6.3 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat FAD_binding_4 PF01565.18 EGG03610.1 - 9.8e-29 99.5 1.9 4.3e-28 97.5 2.0 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EGG03610.1 - 1.5e-09 37.6 1.8 5.3e-09 35.8 1.2 2.0 1 1 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EGG03611.1 - 2.2e-28 98.4 4.9 4.2e-28 97.5 2.1 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EGG03611.1 - 6.7e-15 54.7 1.6 1.3e-14 53.7 1.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EGG03611.1 - 0.0097 15.0 0.1 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.18 EGG03612.1 - 3.5e-30 104.2 2.7 6e-30 103.5 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGG03612.1 - 4e-15 55.4 1.7 8.6e-15 54.3 1.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EGG03612.1 - 0.017 14.3 0.2 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Amidase02_C PF12123.3 EGG03612.1 - 0.082 12.5 0.1 0.91 9.2 0.0 2.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Aldedh PF00171.17 EGG03616.1 - 2.1e-19 69.1 1.1 3.8e-14 51.8 0.1 2.3 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Imm2 PF14426.1 EGG03616.1 - 0.025 14.5 0.3 0.075 13.0 0.0 1.9 2 0 0 2 2 2 0 Immunity protein Imm2 PIG-F PF06699.6 EGG03617.1 - 7.6e-37 127.1 8.8 7.6e-37 127.1 6.1 1.7 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Cation_ATPase_C PF00689.16 EGG03617.1 - 0.0037 16.8 1.5 0.0037 16.8 1.1 2.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus SSP160 PF06933.6 EGG03617.1 - 8.3 4.2 11.0 14 3.4 7.6 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Fip1 PF05182.8 EGG03618.1 - 1.5e-15 56.1 3.2 3e-15 55.2 2.2 1.5 1 0 0 1 1 1 1 Fip1 motif TRI12 PF06609.8 EGG03619.1 - 0.11 10.6 0.1 0.12 10.5 0.1 1.0 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) NUDIX PF00293.23 EGG03621.1 - 1.4e-12 47.3 0.0 2.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Phage_P2_GpE PF06528.7 EGG03621.1 - 0.044 13.2 0.0 0.099 12.1 0.0 1.6 1 0 0 1 1 1 0 Phage P2 GpE DUF1481 PF07356.7 EGG03623.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) p450 PF00067.17 EGG03624.1 - 1.5e-55 188.5 0.0 2.1e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BCS1_N PF08740.6 EGG03625.1 - 2.7e-49 167.3 0.8 3.9e-49 166.8 0.5 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGG03625.1 - 2.3e-19 69.9 0.0 4.1e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGG03625.1 - 1.7e-05 25.5 0.0 3.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGG03625.1 - 0.003 16.9 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGG03625.1 - 0.0052 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG03625.1 - 0.0094 16.2 0.0 0.027 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGG03625.1 - 0.011 15.4 0.0 0.032 13.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EGG03625.1 - 0.018 15.0 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EGG03625.1 - 0.02 14.4 0.0 0.062 12.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.8 EGG03625.1 - 0.021 13.7 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EGG03625.1 - 0.022 14.9 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EGG03625.1 - 0.045 13.6 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EGG03625.1 - 0.11 12.1 0.0 0.33 10.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EGG03625.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EGG03627.1 - 4.8e-13 48.5 23.8 8.5e-13 47.7 16.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Rad51 PF08423.6 EGG03630.1 - 2e-06 26.9 0.0 2.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EGG03630.1 - 0.0041 16.5 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain HCNGP PF07818.8 EGG03633.1 - 0.0022 18.0 0.2 3 7.9 0.0 2.5 3 0 0 3 3 3 2 HCNGP-like protein DUF4380 PF14315.1 EGG03647.1 - 0.0048 16.1 0.1 0.0053 15.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4380) FYVE_2 PF02318.11 EGG03649.1 - 0.35 10.7 2.8 0.46 10.4 1.9 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger FYVE_2 PF02318.11 EGG03650.1 - 0.28 11.1 2.8 0.35 10.7 1.9 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger Cytadhesin_P30 PF07271.6 EGG03654.1 - 0.95 8.6 4.9 1.1 8.4 3.4 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 PUF PF00806.14 EGG03657.1 - 4e-09 35.4 0.0 0.0078 15.6 0.0 5.2 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat VTC PF09359.5 EGG03659.1 - 1.6e-93 312.8 0.1 2.5e-93 312.1 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EGG03659.1 - 3.6e-25 89.2 7.8 3.6e-25 89.2 5.4 3.9 3 1 0 3 3 3 1 SPX domain DUF202 PF02656.10 EGG03659.1 - 2.3e-11 43.7 5.5 5.2e-11 42.6 3.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Hist_deacetyl PF00850.14 EGG03660.1 - 1.1e-90 304.1 0.0 1.8e-90 303.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EGG03660.1 - 3.3e-13 49.4 0.1 5e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Arb2 domain DUF2392 PF10288.4 EGG03662.1 - 1.7e-11 44.3 0.0 3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) JmjC PF02373.17 EGG03663.1 - 3.4e-08 33.7 2.2 9.2e-07 29.1 0.9 2.6 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EGG03663.1 - 3.5e-06 26.6 0.4 1.4e-05 24.7 0.1 1.8 1 1 1 2 2 2 1 Cupin-like domain PHB_acc_N PF07879.6 EGG03663.1 - 0.065 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain ArfGap PF01412.13 EGG03664.1 - 2.4e-33 114.3 0.7 6.6e-33 112.9 0.5 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Peptidase_S30 PF01577.11 EGG03664.1 - 0.044 13.1 1.1 0.083 12.2 0.8 1.4 1 0 0 1 1 1 0 Potyvirus P1 protease Glyco_hydro_47 PF01532.15 EGG03665.1 - 2e-107 359.6 0.7 4.4e-57 193.7 0.1 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Ferritin-like PF12902.2 EGG03667.1 - 0.0092 15.6 0.5 0.011 15.3 0.4 1.1 1 0 0 1 1 1 1 Ferritin-like DUF1057 PF06342.7 EGG03668.1 - 0.023 13.5 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) MBOAT_2 PF13813.1 EGG03669.1 - 0.0012 18.9 2.4 0.0089 16.0 1.2 2.3 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family Trypan_PARP PF05887.6 EGG03670.1 - 2.9e-06 27.1 9.5 4.4e-06 26.5 6.6 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) She9_MDM33 PF05546.6 EGG03670.1 - 0.58 9.6 7.2 0.12 11.8 2.8 1.5 2 0 0 2 2 2 0 She9 / Mdm33 family TRAP_alpha PF03896.11 EGG03670.1 - 2.3 7.1 6.8 4 6.3 4.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PEX11 PF05648.9 EGG03671.1 - 1.9e-17 63.2 3.7 2.2e-17 63.1 2.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ORC6 PF05460.8 EGG03672.1 - 0.48 9.4 11.0 0.97 8.4 7.6 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ndc1_Nup PF09531.5 EGG03672.1 - 4.1 5.7 6.2 6.6 5.0 4.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Baculo_PEP_C PF04513.7 EGG03674.1 - 0.0093 15.7 2.6 0.021 14.6 1.8 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 EGG03674.1 - 0.01 15.3 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MRFAP1 PF15155.1 EGG03674.1 - 0.18 12.1 0.6 0.63 10.3 0.0 2.1 3 0 0 3 3 3 0 MORF4 family-associated protein1 DASH_Dad1 PF08649.5 EGG03675.1 - 5.2e-12 45.2 0.9 5.9e-12 45.0 0.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Thioredoxin PF00085.15 EGG03677.1 - 5.4e-24 83.8 0.1 7.5e-24 83.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGG03677.1 - 5.3e-07 29.8 0.0 1.4e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGG03677.1 - 2.1e-06 27.7 0.0 4.1e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EGG03677.1 - 1.3e-05 24.9 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGG03677.1 - 9e-05 22.0 0.1 0.0002 20.8 0.1 1.6 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 EGG03677.1 - 0.00034 20.5 0.0 0.00055 19.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EGG03677.1 - 0.0018 17.8 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AAA_12 PF13087.1 EGG03679.1 - 1.5e-39 135.4 0.0 1.8e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGG03679.1 - 9.2e-08 31.9 0.3 1.6e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.1 EGG03679.1 - 0.0099 15.3 0.0 0.042 13.3 0.0 1.8 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain FAD_binding_4 PF01565.18 EGG03680.1 - 4.1e-27 94.3 2.5 6.9e-27 93.6 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGG03680.1 - 1.8e-15 56.5 1.3 3.6e-15 55.6 0.9 1.5 1 0 0 1 1 1 1 Berberine and berberine like EXOSC1 PF10447.4 EGG03681.1 - 2.2e-21 75.5 0.6 4.7e-21 74.5 0.4 1.6 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EGG03681.1 - 2e-06 26.9 0.3 3.5e-05 23.0 0.1 2.5 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region Myb_DNA-bind_3 PF12776.2 EGG03683.1 - 7e-08 32.9 2.5 1.5e-07 31.9 1.8 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGG03683.1 - 7.1e-06 26.0 1.8 2e-05 24.6 1.3 1.9 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Pentapeptide_3 PF13576.1 EGG03686.1 - 0.11 12.4 0.4 0.5 10.3 0.1 2.0 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) FAD_binding_4 PF01565.18 EGG03687.1 - 4.9e-24 84.3 3.8 4.9e-24 84.3 2.6 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EGG03687.1 - 2.3e-13 49.8 1.4 4.1e-13 49.0 1.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EGG03687.1 - 0.0069 15.5 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Amidase02_C PF12123.3 EGG03687.1 - 0.064 12.9 0.3 0.96 9.1 0.0 3.1 3 0 0 3 3 3 0 N-acetylmuramoyl-l-alanine amidase Elong_Iki1 PF10483.4 EGG03690.1 - 3e-11 43.2 0.1 3.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 AMP-binding PF00501.23 EGG03691.1 - 3.9e-29 101.2 0.0 4.8e-28 97.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme DUF3105 PF11303.3 EGG03691.1 - 6.6e-05 22.7 0.0 0.28 11.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3105) RNA_pol_Rpb5_C PF01191.14 EGG03691.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain PNK3P PF08645.6 EGG03692.1 - 2.5e-54 183.0 0.1 5.3e-54 181.9 0.1 1.6 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EGG03692.1 - 3.8e-24 85.1 0.0 1.7e-20 73.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain KTI12 PF08433.5 EGG03692.1 - 0.059 12.5 0.2 0.65 9.1 0.1 2.1 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Glyco_hydro_35 PF01301.14 EGG03693.1 - 2.6e-72 243.8 0.2 4.7e-72 243.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EGG03693.1 - 5.1e-34 116.8 0.1 5.2e-16 58.8 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EGG03693.1 - 4.2e-18 65.3 0.9 1.3e-17 63.7 0.6 1.8 1 1 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EGG03693.1 - 2.9e-09 36.1 0.0 6.7e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 AAA_17 PF13207.1 EGG03696.1 - 2.4e-08 34.8 0.0 2.5e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EGG03696.1 - 1.5e-07 31.4 0.0 1.7e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 EGG03696.1 - 1.5e-05 24.9 0.0 1.5e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG03696.1 - 1.8e-05 25.0 0.0 1.8e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EGG03696.1 - 0.00036 20.2 0.0 0.00041 20.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase Rad17 PF03215.10 EGG03696.1 - 0.00038 19.2 0.2 0.0009 18.0 0.1 1.6 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EGG03696.1 - 0.00044 20.3 0.0 0.00052 20.1 0.0 1.1 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EGG03696.1 - 0.00056 20.0 0.0 0.00056 20.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EGG03696.1 - 0.00084 19.5 0.0 0.00099 19.3 0.0 1.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGG03696.1 - 0.0012 18.7 0.0 0.0014 18.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EGG03696.1 - 0.0012 18.3 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.1 EGG03696.1 - 0.0013 18.6 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_16 PF13191.1 EGG03696.1 - 0.0017 18.3 0.0 0.0017 18.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EGG03696.1 - 0.0032 16.4 0.0 0.0032 16.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Hpr_kinase_C PF07475.7 EGG03696.1 - 0.0055 16.0 0.0 0.0056 16.0 0.0 1.1 1 0 0 1 1 1 1 HPr Serine kinase C-terminal domain PRK PF00485.13 EGG03696.1 - 0.0079 15.7 0.0 0.0079 15.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family IPT PF01745.11 EGG03696.1 - 0.0084 15.3 0.0 0.0086 15.2 0.0 1.0 1 0 0 1 1 1 1 Isopentenyl transferase AAA_5 PF07728.9 EGG03696.1 - 0.01 15.6 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 EGG03696.1 - 0.015 15.0 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EGG03696.1 - 0.018 15.3 0.1 0.02 15.1 0.1 1.3 1 1 0 1 1 1 0 ABC transporter AAA_31 PF13614.1 EGG03696.1 - 0.021 14.7 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain CoaE PF01121.15 EGG03696.1 - 0.021 14.1 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_19 PF13245.1 EGG03696.1 - 0.024 14.3 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 EGG03696.1 - 0.029 14.3 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain tRNA_lig_kinase PF08303.6 EGG03696.1 - 0.034 14.0 0.0 0.034 14.0 0.0 1.1 1 0 0 1 1 1 0 tRNA ligase kinase domain DUF258 PF03193.11 EGG03696.1 - 0.037 13.2 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CbiA PF01656.18 EGG03696.1 - 0.039 13.3 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Arch_ATPase PF01637.13 EGG03696.1 - 0.047 13.3 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 EGG03696.1 - 0.049 13.0 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EGG03696.1 - 0.082 12.3 0.0 0.095 12.1 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MobB PF03205.9 EGG03696.1 - 0.097 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EGG03696.1 - 0.12 11.2 0.2 0.13 11.0 0.1 1.3 1 1 0 1 1 1 0 NB-ARC domain KTI12 PF08433.5 EGG03696.1 - 0.12 11.5 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 OHCU_decarbox PF09349.5 EGG03697.1 - 1.1e-27 97.2 0.0 1.8e-27 96.5 0.0 1.3 1 1 0 1 1 1 1 OHCU decarboxylase UQ_con PF00179.21 EGG03698.1 - 1.1e-40 138.2 0.0 1.4e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EGG03698.1 - 2.4e-13 49.4 0.0 3.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_2 PF08587.6 EGG03698.1 - 0.0082 16.3 0.3 0.031 14.4 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin associated domain (UBA) F-box PF00646.28 EGG03702.1 - 0.022 14.3 0.0 0.076 12.6 0.0 1.9 1 1 0 1 1 1 0 F-box domain F-box PF00646.28 EGG03703.1 - 0.23 11.1 3.4 0.71 9.6 0.3 3.0 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 EGG03703.1 - 0.59 9.9 3.8 0.21 11.3 0.3 2.1 2 1 0 2 2 2 0 F-box-like BRO1 PF03097.13 EGG03704.1 - 2.6e-102 342.3 7.3 5.9e-102 341.2 0.4 2.2 2 0 0 2 2 2 2 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EGG03704.1 - 2e-55 187.8 15.6 3.5e-55 187.0 10.8 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV ATLF PF07737.6 EGG03704.1 - 0.011 15.1 0.6 2.9 7.2 0.0 3.1 3 0 0 3 3 3 0 Anthrax toxin lethal factor, N- and C-terminal domain Yip1 PF04893.12 EGG03705.1 - 5.8e-08 32.4 15.2 1.6e-07 30.9 10.5 1.6 1 1 0 1 1 1 1 Yip1 domain CAAD PF14159.1 EGG03705.1 - 0.18 11.4 5.7 0.14 11.8 0.6 2.6 1 1 1 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Epimerase PF01370.16 EGG03706.1 - 1.1e-40 139.5 0.0 1.6e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EGG03706.1 - 2.5e-24 84.9 0.0 4.3e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 EGG03706.1 - 1.3e-14 53.8 0.0 1.1e-13 50.7 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EGG03706.1 - 3.7e-14 52.1 0.0 1.3e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGG03706.1 - 1.6e-13 50.2 0.0 2.4e-13 49.6 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EGG03706.1 - 8.7e-10 37.9 0.0 1.3e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGG03706.1 - 0.00017 21.6 0.0 0.00041 20.3 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EGG03706.1 - 0.009 15.6 0.0 0.017 14.7 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EGG03706.1 - 0.012 15.5 0.0 0.029 14.2 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase PBP PF01161.15 EGG03707.1 - 1.2e-16 60.8 0.1 4.2e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylethanolamine-binding protein MRP-L51 PF10244.4 EGG03707.1 - 0.032 14.2 0.0 7 6.7 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal subunit PBP PF01161.15 EGG03708.1 - 1.6e-06 28.0 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3640 PF12342.3 EGG03709.1 - 0.023 14.1 5.0 0.84 9.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3640) Pro_isomerase PF00160.16 EGG03710.1 - 2.7e-48 164.1 0.5 3e-48 163.9 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Polysacc_deac_1 PF01522.16 EGG03711.1 - 5.4e-33 113.2 0.0 1.4e-32 111.9 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGG03711.1 - 0.0013 17.7 0.0 0.0037 16.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Toxin_31 PF08119.6 EGG03712.1 - 0.038 13.5 0.1 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Scorpion acidic alpha-KTx toxin family zf-C3HC4_3 PF13920.1 EGG03713.1 - 2.2e-08 33.6 5.2 3.9e-08 32.8 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG03713.1 - 6.3e-08 32.5 10.5 1.2e-07 31.6 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EGG03713.1 - 6.4e-08 32.0 2.3 6.4e-08 32.0 1.6 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 EGG03713.1 - 4.5e-06 26.2 9.1 8.2e-06 25.4 6.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGG03713.1 - 1.1e-05 25.0 7.8 1.9e-05 24.3 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGG03713.1 - 4.8e-05 22.9 10.1 9.2e-05 22.0 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGG03713.1 - 0.0018 17.9 6.5 0.0038 16.9 4.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGG03713.1 - 0.0026 17.6 8.2 0.0026 17.6 5.6 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EGG03713.1 - 0.0051 16.3 3.6 0.0077 15.7 2.5 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RanBP PF00641.13 EGG03713.1 - 0.014 14.4 1.6 0.014 14.4 1.1 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-RING_6 PF14835.1 EGG03713.1 - 0.35 10.6 3.4 0.71 9.6 2.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein BmKX PF09132.5 EGG03713.1 - 2 8.3 5.2 0.56 10.1 0.7 2.2 2 0 0 2 2 2 0 BmKX zf-rbx1 PF12678.2 EGG03713.1 - 3.8 7.6 7.9 16 5.6 5.5 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger Peptidase_C78 PF07910.8 EGG03715.1 - 6.4e-47 159.4 0.2 1.4e-36 125.6 0.0 2.4 1 1 1 2 2 2 2 Peptidase family C78 Pyr_redox_3 PF13738.1 EGG03716.1 - 3e-22 79.6 0.0 2.9e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGG03716.1 - 4.2e-15 54.9 0.0 3.1e-13 48.8 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EGG03716.1 - 1.8e-11 43.5 0.0 1.7e-07 30.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGG03716.1 - 7.1e-08 32.5 0.0 2.9e-06 27.2 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGG03716.1 - 2.5e-07 29.9 0.0 0.006 15.5 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGG03716.1 - 7.5e-06 25.2 0.0 3.3e-05 23.1 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 EGG03716.1 - 9.3e-06 24.3 0.0 0.00026 19.5 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EGG03716.1 - 2.3e-05 24.6 0.2 0.22 11.9 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGG03716.1 - 7.6e-05 22.6 0.0 0.00023 21.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGG03716.1 - 0.00025 20.8 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EGG03716.1 - 0.00046 20.2 0.1 0.22 11.6 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EGG03716.1 - 0.0013 17.6 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EGG03716.1 - 0.0018 17.1 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EGG03716.1 - 0.0019 17.2 0.2 0.12 11.2 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 EGG03716.1 - 0.022 13.8 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EGG03716.1 - 0.026 13.5 0.0 0.19 10.7 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 EGG03716.1 - 0.075 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EGG03716.1 - 0.087 12.4 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGG03716.1 - 0.18 11.7 0.0 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain COesterase PF00135.23 EGG03717.1 - 3.3e-94 316.5 0.0 4.6e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGG03717.1 - 0.00031 20.3 0.1 0.0021 17.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGG03717.1 - 0.0018 17.5 0.5 0.0031 16.7 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family SLH PF00395.15 EGG03718.1 - 0.021 14.5 0.1 0.079 12.7 0.1 2.0 1 0 0 1 1 1 0 S-layer homology domain Pkinase PF00069.20 EGG03720.1 - 1.3e-38 132.6 0.0 1.7e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG03720.1 - 5.1e-28 97.8 0.0 6.2e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG03720.1 - 0.00033 19.7 0.0 0.00049 19.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGG03720.1 - 0.001 18.8 0.0 0.68 9.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGG03720.1 - 0.0033 16.5 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4218 PF13960.1 EGG03721.1 - 0.032 13.6 0.1 0.084 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) tRNA-synt_His PF13393.1 EGG03722.1 - 4.9e-42 144.0 0.0 3.3e-36 124.9 0.0 2.3 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EGG03722.1 - 6.2e-21 74.7 0.0 1.3e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGG03722.1 - 2.2e-09 37.1 0.1 6.4e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.15 EGG03722.1 - 1.1e-06 28.1 0.9 3.3e-06 26.6 0.2 2.2 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_2 PF00152.15 EGG03722.1 - 3.8e-06 25.9 0.2 0.00052 18.8 0.3 2.7 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 EGG03722.1 - 0.01 15.0 0.3 0.01 15.0 0.2 2.5 3 0 0 3 3 3 0 Anticodon binding domain of tRNAs XAP5 PF04921.9 EGG03727.1 - 2.6e-90 302.1 5.3 2.6e-90 302.1 3.7 2.1 1 1 1 2 2 2 1 XAP5, circadian clock regulator CD99L2 PF12301.3 EGG03727.1 - 0.0051 16.5 4.9 0.0085 15.7 3.4 1.3 1 0 0 1 1 1 1 CD99 antigen like protein 2 Mem_trans PF03547.13 EGG03727.1 - 0.078 11.2 1.8 0.09 11.0 1.3 1.1 1 0 0 1 1 1 0 Membrane transport protein Seipin PF06775.9 EGG03728.1 - 2.9e-43 147.7 0.1 4.2e-43 147.1 0.1 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF1199 PF06712.6 EGG03728.1 - 0.094 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) HIG_1_N PF04588.8 EGG03729.1 - 9.2e-06 25.3 0.9 9.2e-06 25.3 0.6 2.7 4 0 0 4 4 4 1 Hypoxia induced protein conserved region DUF1689 PF07954.6 EGG03729.1 - 0.32 10.8 2.0 0.96 9.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1689) HlyD PF00529.15 EGG03730.1 - 7 5.8 13.9 7.3 5.8 8.8 1.6 2 0 0 2 2 2 0 HlyD family secretion protein Pox_A_type_inc PF04508.7 EGG03730.1 - 8.3 6.4 8.0 0.67 9.8 1.5 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat TCTP PF00838.12 EGG03731.1 - 5.5e-65 218.3 1.3 6.1e-65 218.2 0.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein MDM31_MDM32 PF08118.6 EGG03733.1 - 1.6e-111 373.2 0.0 3.7e-87 292.8 0.0 2.1 1 1 0 2 2 2 2 Yeast mitochondrial distribution and morphology (MDM) proteins MASE1 PF05231.9 EGG03733.1 - 0.0016 17.5 0.7 0.0025 16.8 0.5 1.2 1 0 0 1 1 1 1 MASE1 UDPGP PF01704.13 EGG03734.1 - 1.6e-182 606.6 0.1 1.9e-182 606.4 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase EamA PF00892.15 EGG03735.1 - 1.3e-10 41.4 40.3 1.4e-05 25.0 10.3 3.0 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 EGG03735.1 - 3.8e-09 36.3 16.0 3.8e-09 36.3 11.1 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF2648 PF10855.3 EGG03735.1 - 0.091 12.1 0.1 2 7.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) CcoS PF03597.10 EGG03735.1 - 0.14 11.6 0.1 0.14 11.6 0.0 3.1 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type Rhodanese PF00581.15 EGG03740.1 - 0.0046 17.2 0.1 0.041 14.2 0.1 2.4 2 1 0 2 2 2 1 Rhodanese-like domain GBP PF02263.14 EGG03740.1 - 0.047 12.7 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain DUF2733 PF10813.3 EGG03740.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) DUF236 PF03057.9 EGG03741.1 - 0.00018 21.5 1.1 0.00036 20.5 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function zf-C2H2_4 PF13894.1 EGG03742.1 - 3.3e-05 23.9 8.8 0.011 16.0 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGG03742.1 - 0.00011 22.3 10.3 0.027 14.8 0.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG03742.1 - 0.0016 18.6 6.2 0.0016 18.6 4.3 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGG03742.1 - 0.0094 15.8 2.6 0.0094 15.8 1.8 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger BSD PF03909.12 EGG03743.1 - 1.3e-10 40.8 0.9 3.4e-10 39.5 0.1 2.1 2 0 0 2 2 2 1 BSD domain B2 PF11473.3 EGG03743.1 - 0.06 12.9 0.1 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA binding protein B2 Glycos_trans_3N PF02885.12 EGG03747.1 - 0.12 11.9 0.1 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain DUF1708 PF08101.6 EGG03753.1 - 2.6e-21 75.9 0.1 4.1e-20 72.0 0.0 2.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 EGG03753.1 - 9.3e-08 31.8 0.0 1.6e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain Suf PF05843.9 EGG03753.1 - 0.9 9.2 6.0 0.075 12.7 0.4 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF883 PF05957.8 EGG03755.1 - 0.17 12.3 6.8 0.59 10.5 4.7 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DivIVA PF05103.8 EGG03755.1 - 4.6 7.3 8.4 7.9 6.5 5.8 1.4 1 1 0 1 1 1 0 DivIVA protein YtxH PF12732.2 EGG03755.1 - 6.5 7.1 9.3 1e+02 3.3 6.5 2.1 1 1 0 1 1 1 0 YtxH-like protein Aminotran_1_2 PF00155.16 EGG03756.1 - 9.1e-58 195.9 0.0 1e-57 195.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EGG03756.1 - 2.7e-08 33.2 0.0 4.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EGG03756.1 - 2.3e-06 26.1 0.0 5e-06 25.0 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EGG03756.1 - 0.0001 21.6 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2240 PF09999.4 EGG03756.1 - 0.025 14.0 0.1 6.5 6.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2240) Aminotran_5 PF00266.14 EGG03756.1 - 0.03 13.0 0.0 0.051 12.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V DUF3410 PF11890.3 EGG03756.1 - 0.21 11.2 0.6 6.6 6.4 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3410) SUI1 PF01253.17 EGG03758.1 - 2.2e-21 75.4 0.8 4.2e-21 74.5 0.5 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 RAP1 PF07218.6 EGG03759.1 - 0.00084 17.5 11.5 0.0012 17.0 8.0 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Syntaxin-6_N PF09177.6 EGG03759.1 - 0.03 14.7 4.3 0.07 13.5 3.0 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TBPIP PF07106.8 EGG03759.1 - 0.2 11.2 7.3 0.39 10.2 5.0 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 EGG03759.1 - 0.32 9.3 4.5 0.47 8.8 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GEMIN8 PF15348.1 EGG03759.1 - 5.5 6.9 12.5 3.9 7.4 7.3 1.6 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Clr5 PF14420.1 EGG03761.1 - 0.00087 19.1 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 Clr5 domain Rhomboid PF01694.17 EGG03762.1 - 1.8e-06 28.0 4.8 1.8e-06 28.0 3.3 1.9 2 1 0 2 2 2 1 Rhomboid family DUF1751 PF08551.5 EGG03762.1 - 0.0027 18.0 4.0 0.023 15.0 2.0 2.4 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Nup160 PF11715.3 EGG03762.1 - 0.0063 14.7 0.0 0.0074 14.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 KdpC PF02669.10 EGG03762.1 - 0.16 11.6 0.2 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Far-17a_AIG1 PF04750.9 EGG03763.1 - 8.1e-11 41.4 6.7 8.8e-11 41.3 4.6 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Prenyltrans PF00432.16 EGG03764.1 - 5.3e-28 96.2 9.7 5.9e-08 32.1 0.0 5.5 5 2 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGG03764.1 - 8.3e-14 51.9 0.0 1.6e-11 44.5 0.0 3.1 1 1 1 3 3 3 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGG03764.1 - 7.6e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Prenyltransferase-like Sec6 PF06046.8 EGG03764.1 - 0.0039 15.3 0.0 0.032 12.3 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec6 GSH_synth_ATP PF03917.12 EGG03765.1 - 4.8e-93 311.6 0.0 5.8e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EGG03765.1 - 1.2e-26 92.8 0.0 2.1e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase MCPVI PF02993.9 EGG03767.1 - 1.5 8.8 7.3 0.22 11.6 0.5 2.2 1 1 1 2 2 2 0 Minor capsid protein VI SprT-like PF10263.4 EGG03768.1 - 2.5e-25 88.9 0.2 4.6e-25 88.0 0.1 1.3 1 0 0 1 1 1 1 SprT-like family DUF3521 PF12035.3 EGG03768.1 - 0.072 12.9 1.3 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) PBP1_TM PF14812.1 EGG03768.1 - 0.2 12.0 5.4 0.83 10.0 3.7 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MBOAT_2 PF13813.1 EGG03769.1 - 8.7e-07 28.9 9.4 3.6e-06 26.9 4.1 2.9 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family MAPEG PF01124.13 EGG03770.1 - 3.4e-23 81.6 1.5 4e-23 81.4 1.0 1.1 1 0 0 1 1 1 1 MAPEG family Gar1 PF04410.9 EGG03774.1 - 2.6e-35 121.1 0.1 2.6e-35 121.1 0.0 3.4 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region EF-1_beta_acid PF10587.4 EGG03774.1 - 3 8.0 7.6 11 6.2 0.1 3.0 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region ETC_C1_NDUFA4 PF04800.7 EGG03775.1 - 3.4e-35 119.9 0.3 4.1e-35 119.6 0.2 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region Pkinase PF00069.20 EGG03778.1 - 6.9e-65 218.7 0.0 8.3e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG03778.1 - 2.9e-34 118.3 0.0 3.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF605 PF04652.11 EGG03778.1 - 2.8 7.2 8.1 3.8 6.7 5.6 1.1 1 0 0 1 1 1 0 Vta1 like GYF PF02213.11 EGG03780.1 - 7.9e-16 57.3 0.0 1.8e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 GYF domain DUF2889 PF11136.3 EGG03782.1 - 0.056 13.6 0.1 0.076 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2889) Ribosomal_L37e PF01907.14 EGG03782.1 - 0.19 11.5 1.0 4.8 7.0 0.0 2.3 1 1 1 2 2 2 0 Ribosomal protein L37e ATP-grasp_2 PF08442.5 EGG03783.1 - 7.9e-68 227.8 0.0 1.4e-67 227.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EGG03783.1 - 5.7e-24 84.4 2.1 8.7e-24 83.8 0.6 1.9 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 EGG03783.1 - 2.1e-12 46.7 0.5 4e-12 45.8 0.0 1.7 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EGG03783.1 - 1.5e-05 24.6 0.0 0.00012 21.7 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 EGG03783.1 - 9.8e-05 21.7 0.2 0.00025 20.3 0.1 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 EGG03783.1 - 0.00059 19.6 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EGG03783.1 - 0.002 17.5 0.0 0.0056 16.0 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EGG03783.1 - 0.035 13.6 0.0 0.13 11.7 0.0 1.9 1 1 1 2 2 2 0 RimK-like ATP-grasp domain HipA_N PF07805.7 EGG03783.1 - 0.056 13.6 0.0 0.23 11.7 0.0 2.0 1 0 0 1 1 1 0 HipA-like N-terminal domain GMC_oxred_N PF00732.14 EGG03784.1 - 2.8e-50 171.1 0.4 4.4e-50 170.5 0.3 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGG03784.1 - 2.5e-24 86.2 0.0 5.1e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EGG03784.1 - 6e-08 31.9 0.1 8.9e-06 24.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGG03784.1 - 9.3e-06 25.5 0.1 0.0001 22.2 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGG03784.1 - 3.4e-05 22.8 0.7 0.00012 21.1 0.5 1.8 1 1 0 1 1 1 1 FAD binding domain GDI PF00996.13 EGG03784.1 - 0.0001 20.7 0.1 0.00023 19.6 0.1 1.5 2 0 0 2 2 2 1 GDP dissociation inhibitor FAD_binding_3 PF01494.14 EGG03784.1 - 0.00048 19.2 0.0 0.00074 18.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGG03784.1 - 0.00068 18.2 0.2 0.0078 14.7 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EGG03784.1 - 0.0024 17.0 0.2 0.0067 15.5 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EGG03784.1 - 0.0057 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EGG03784.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HCaRG PF07258.9 EGG03784.1 - 0.023 14.2 1.5 0.042 13.4 1.1 1.3 1 0 0 1 1 1 0 HCaRG protein Trp_halogenase PF04820.9 EGG03784.1 - 0.051 12.2 0.0 0.076 11.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 EGG03784.1 - 0.068 13.5 0.1 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGG03784.1 - 0.081 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EGG03784.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 EGG03784.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EGG03784.1 - 0.19 11.3 0.1 0.47 10.0 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 EGG03785.1 - 1.3e-60 204.7 0.0 1.5e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG03785.1 - 8.1e-43 146.3 0.0 1e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG03785.1 - 4.8e-06 25.7 0.0 7.4e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGG03785.1 - 0.0056 16.4 0.4 0.063 13.0 0.1 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGG03785.1 - 0.013 14.3 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EGG03785.1 - 0.017 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EGG03785.1 - 0.096 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Band_3_cyto PF07565.8 EGG03786.1 - 0.0061 16.1 1.9 0.0061 16.1 1.3 1.7 2 0 0 2 2 2 1 Band 3 cytoplasmic domain Ndc1_Nup PF09531.5 EGG03786.1 - 2.1 6.6 8.0 2.9 6.1 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sad1_UNC PF07738.8 EGG03787.1 - 2.3e-23 82.5 0.0 3e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.20 EGG03787.1 - 0.0016 18.3 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain MFS_1 PF07690.11 EGG03789.1 - 3.8e-16 58.7 41.4 3.8e-15 55.4 28.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGG03789.1 - 8.7e-14 50.6 18.7 1.2e-13 50.1 13.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 EGG03789.1 - 0.021 14.7 3.1 0.049 13.5 1.0 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 UQ_con PF00179.21 EGG03790.1 - 9.3e-12 44.5 0.0 2.5e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.26 EGG03790.1 - 9e-09 34.9 0.2 2.5e-08 33.5 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain IBR PF01485.16 EGG03790.1 - 0.001 18.8 2.1 0.002 17.9 1.4 1.4 1 0 0 1 1 1 1 IBR domain UAA PF08449.6 EGG03791.1 - 3.2e-72 243.0 13.6 6e-72 242.1 9.4 1.4 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EGG03791.1 - 1.7e-07 31.4 19.1 4.5e-06 26.8 2.5 4.1 4 1 0 4 4 4 2 Multidrug resistance efflux transporter EamA PF00892.15 EGG03791.1 - 2.7e-05 24.2 10.6 2.7e-05 24.2 7.3 4.2 3 1 2 5 5 5 1 EamA-like transporter family Nuc_sug_transp PF04142.10 EGG03791.1 - 0.00011 21.3 3.9 0.13 11.3 0.1 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 EGG03791.1 - 0.066 12.8 16.9 0.039 13.6 8.3 2.8 2 1 0 2 2 2 0 Triose-phosphate Transporter family Wzy_C PF04932.10 EGG03791.1 - 2.4 7.9 8.4 0.084 12.6 0.3 2.5 2 1 1 3 3 3 0 O-Antigen ligase UPF0546 PF10639.4 EGG03791.1 - 2.4 7.9 8.5 3.9 7.3 0.8 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 Cation_ATPase_C PF00689.16 EGG03791.1 - 3 7.3 12.9 2.8 7.4 6.5 2.6 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus NUDIX PF00293.23 EGG03792.1 - 1.5e-11 44.0 0.0 1.5e-09 37.6 0.0 2.3 1 1 0 1 1 1 1 NUDIX domain UCH PF00443.24 EGG03793.1 - 5.9e-58 196.1 0.0 9.5e-58 195.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGG03793.1 - 2.7e-33 115.7 0.1 3.9e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EGG03793.1 - 0.006 15.9 4.6 0.25 10.6 1.6 3.2 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase ABC_tran PF00005.22 EGG03794.1 - 9.5e-41 139.3 0.0 1.5e-26 93.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGG03794.1 - 2.1e-35 122.4 19.5 5.4e-19 68.6 7.5 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EGG03794.1 - 8e-09 35.0 0.0 0.0062 15.7 1.8 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGG03794.1 - 4e-06 26.9 0.1 0.023 14.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGG03794.1 - 5.2e-06 26.6 0.0 0.0053 16.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EGG03794.1 - 7.5e-06 26.4 0.1 0.03 14.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGG03794.1 - 6.2e-05 22.4 0.1 0.39 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGG03794.1 - 7.9e-05 22.1 0.0 0.41 10.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGG03794.1 - 0.0044 17.0 0.2 0.097 12.6 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain KaiC PF06745.8 EGG03794.1 - 0.014 14.5 0.4 4 6.4 0.0 2.5 2 0 0 2 2 2 0 KaiC FtsK_SpoIIIE PF01580.13 EGG03794.1 - 0.017 14.6 0.0 5.4 6.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 EGG03794.1 - 0.035 13.0 0.0 0.85 8.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.1 EGG03794.1 - 0.071 13.0 0.0 0.44 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EGG03794.1 - 0.1 11.4 0.0 0.31 9.8 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 EGG03794.1 - 0.11 13.3 0.5 0.26 12.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EGG03794.1 - 0.3 10.7 2.4 1 8.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EGG03794.1 - 0.43 10.8 0.6 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain SOG2 PF10428.4 EGG03795.1 - 1.6 7.2 6.4 2.9 6.4 4.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein GDPD PF03009.12 EGG03796.1 - 2.3e-33 115.7 0.0 4.1e-33 114.9 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EGG03796.1 - 0.0064 16.6 0.6 0.038 14.1 0.4 2.2 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family RPN7 PF10602.4 EGG03797.1 - 4.9e-38 130.2 1.5 8.8e-38 129.4 1.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EGG03797.1 - 2.8e-09 37.2 0.3 7.5e-08 32.6 0.0 3.0 2 2 1 3 3 3 1 PCI domain TPR_2 PF07719.12 EGG03797.1 - 0.0052 16.6 3.7 6.1 7.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Mit_ribos_Mrp51 PF11709.3 EGG03797.1 - 0.086 12.0 0.7 0.15 11.2 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit TPR_12 PF13424.1 EGG03797.1 - 1.6 8.7 8.0 0.38 10.7 0.8 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Nop14 PF04147.7 EGG03798.1 - 9.2e-214 711.9 14.3 1.1e-213 711.7 9.9 1.0 1 0 0 1 1 1 1 Nop14-like family DUF500 PF04366.7 EGG03801.1 - 9.9e-37 125.1 1.3 1.7e-36 124.4 0.9 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EGG03801.1 - 3.8e-13 48.6 0.2 9.5e-13 47.3 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGG03801.1 - 6.5e-12 44.7 0.0 3.6e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EGG03801.1 - 2.2e-11 43.1 0.1 1.2e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain GATA-N PF05349.7 EGG03801.1 - 0.011 15.9 0.2 0.023 14.8 0.1 1.5 1 0 0 1 1 1 0 GATA-type transcription activator, N-terminal SUFU_C PF12470.3 EGG03803.1 - 9.9 5.7 8.1 11 5.5 4.7 1.7 2 1 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain Cwf_Cwc_15 PF04889.7 EGG03807.1 - 3e-70 236.7 33.0 8.6e-69 231.9 22.9 2.0 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.7 EGG03807.1 - 0.014 13.7 28.2 0.018 13.4 19.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GED PF02212.13 EGG03807.1 - 8 6.4 14.4 3.2 7.7 3.4 3.4 4 0 0 4 4 4 0 Dynamin GTPase effector domain PLATZ PF04640.9 EGG03809.1 - 0.022 14.9 0.2 0.062 13.5 0.1 1.7 1 0 0 1 1 1 0 PLATZ transcription factor OMPdecase PF00215.19 EGG03810.1 - 1.4e-08 34.3 0.1 1.6e-08 34.2 0.1 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Vac_Fusion PF02346.11 EGG03810.1 - 0.0091 15.3 0.2 0.75 9.2 0.0 2.4 3 0 0 3 3 3 2 Chordopoxvirus fusion protein OMPdecase PF00215.19 EGG03811.1 - 1e-08 34.8 0.0 1.2e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family RhoGAP PF00620.22 EGG03813.1 - 9.4e-44 148.6 0.1 1e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain CBS PF00571.23 EGG03814.1 - 5.7e-39 131.6 6.3 2.9e-09 36.5 0.0 4.5 4 0 0 4 4 4 4 CBS domain PB1 PF00564.19 EGG03814.1 - 7.2e-05 22.3 0.3 0.00021 20.9 0.2 1.8 1 0 0 1 1 1 1 PB1 domain ACPS PF01648.15 EGG03815.1 - 3.6e-10 39.6 0.0 5.3e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily MIP-T3 PF10243.4 EGG03816.1 - 2.8 6.2 11.6 3.7 5.8 8.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1180 PF06679.7 EGG03817.1 - 1.8 8.4 6.2 0.77 9.6 2.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Syntaxin-6_N PF09177.6 EGG03818.1 - 0.0092 16.3 0.1 0.032 14.6 0.1 2.1 1 0 0 1 1 1 1 Syntaxin 6, N-terminal RhoGEF PF00621.15 EGG03819.1 - 4.8e-32 111.2 7.4 7.1e-30 104.2 0.2 3.6 4 1 0 4 4 4 2 RhoGEF domain HAD_2 PF13419.1 EGG03820.1 - 1.2e-15 58.1 0.1 6.3e-10 39.5 0.0 3.0 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGG03820.1 - 8.1e-11 42.7 0.0 2.4e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGG03820.1 - 1.9e-07 30.6 0.0 3.8e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Corona_nucleoca PF00937.13 EGG03820.1 - 0.0025 16.8 5.9 0.0038 16.2 4.1 1.2 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein HAD PF12710.2 EGG03820.1 - 0.027 14.6 0.0 0.066 13.3 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase eIF-3_zeta PF05091.7 EGG03823.1 - 2.4e-172 574.1 0.0 1.6e-171 571.4 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Cyclin PF08613.6 EGG03825.1 - 4.5e-20 72.5 0.4 4.5e-20 72.5 0.3 2.0 2 0 0 2 2 2 1 Cyclin DUF1667 PF07892.6 EGG03825.1 - 0.14 11.9 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) Suf PF05843.9 EGG03826.1 - 1.2e-68 231.9 0.0 8.5e-67 225.8 0.0 3.4 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EGG03826.1 - 0.00016 22.2 0.5 0.0072 16.9 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGG03826.1 - 0.0076 16.7 4.6 0.26 12.0 0.0 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGG03826.1 - 0.087 13.3 1.5 0.67 10.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SelB-wing_2 PF09106.6 EGG03826.1 - 0.093 12.6 0.1 0.33 10.9 0.1 1.9 1 0 0 1 1 1 0 Elongation factor SelB, winged helix TPP_enzyme_M PF00205.17 EGG03829.1 - 2.8e-05 23.9 0.0 3.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain PUF PF00806.14 EGG03829.1 - 0.01 15.2 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Glutaredoxin PF00462.19 EGG03830.1 - 1.7e-12 47.1 0.1 3.3e-12 46.1 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 EGG03830.1 - 0.0036 17.5 0.0 0.0057 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 EGG03830.1 - 0.0049 16.6 0.0 0.045 13.5 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin domain Zn_ribbon_2 PF12674.2 EGG03830.1 - 0.072 13.4 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative zinc ribbon domain Thioredoxin_2 PF13098.1 EGG03830.1 - 0.094 12.9 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Peroxidase_2 PF01328.12 EGG03833.1 - 7.2e-13 47.8 0.1 5.4e-10 38.4 0.0 2.1 2 0 0 2 2 2 2 Peroxidase, family 2 GWT1 PF06423.7 EGG03834.1 - 1.4e-25 89.9 3.5 1.7e-25 89.7 0.2 2.8 2 1 0 2 2 2 1 GWT1 Pkinase PF00069.20 EGG03838.1 - 1.8e-60 204.3 0.0 2e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG03838.1 - 1.3e-39 135.8 0.0 1.8e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG03838.1 - 3.7e-11 42.5 0.0 2.1e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EGG03838.1 - 0.0035 16.2 0.0 0.0052 15.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EGG03838.1 - 0.014 15.1 0.1 0.041 13.6 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGG03838.1 - 0.068 12.2 0.1 0.14 11.2 0.1 1.5 1 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4614 PF15391.1 EGG03839.1 - 0.22 11.3 10.4 0.34 10.6 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SoxE PF06525.6 EGG03839.1 - 0.55 9.4 8.6 1 8.5 5.9 1.4 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Pkinase PF00069.20 EGG03840.1 - 2.1e-62 210.6 0.0 2.4e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG03840.1 - 2.9e-35 121.5 0.0 3.5e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG03840.1 - 1.2e-05 24.3 0.0 1.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EGG03840.1 - 0.0045 16.3 0.0 0.0092 15.3 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EGG03840.1 - 0.014 15.1 0.1 0.087 12.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Neil1-DNA_bind PF09292.5 EGG03840.1 - 0.017 14.8 0.1 0.044 13.5 0.0 1.7 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind Kdo PF06293.9 EGG03840.1 - 0.029 13.4 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C2 PF00648.16 EGG03841.1 - 3.7e-16 58.9 0.0 6.1e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EGG03841.1 - 2.1e-12 46.9 0.0 6.4e-12 45.3 0.0 1.8 1 1 0 1 1 1 1 Calpain large subunit, domain III MIT PF04212.13 EGG03841.1 - 1.3e-11 44.2 0.0 2.3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TruB_N PF01509.13 EGG03842.1 - 1.1e-35 123.0 0.0 1.4e-34 119.3 0.0 2.1 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) XdhC_CoxI PF02625.11 EGG03842.1 - 0.074 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 XdhC and CoxI family PseudoU_synth_2 PF00849.17 EGG03842.1 - 0.11 12.2 0.1 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 RNA pseudouridylate synthase ABC_tran PF00005.22 EGG03843.1 - 3.6e-48 163.3 0.0 4.1e-29 101.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGG03843.1 - 1.5e-43 149.2 21.0 3e-23 82.6 2.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EGG03843.1 - 9.6e-12 45.4 0.1 1.4e-05 25.1 0.0 4.4 5 0 0 5 5 5 2 AAA domain SMC_N PF02463.14 EGG03843.1 - 1.1e-08 34.6 5.2 0.0005 19.3 0.0 4.8 4 1 1 5 5 5 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGG03843.1 - 1.4e-07 30.9 0.3 0.022 14.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGG03843.1 - 2e-07 31.1 1.4 0.0026 17.7 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EGG03843.1 - 1.2e-06 29.3 0.3 0.00093 20.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EGG03843.1 - 1.9e-05 24.1 0.3 0.024 14.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGG03843.1 - 8.8e-05 22.8 0.1 0.14 12.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EGG03843.1 - 0.00031 20.4 0.2 0.24 11.1 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 EGG03843.1 - 0.00099 18.6 0.8 1.9 7.8 0.1 3.1 3 0 0 3 3 3 2 AAA-like domain DUF87 PF01935.12 EGG03843.1 - 0.0055 16.5 0.6 2.1 8.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EGG03843.1 - 0.0056 16.8 2.3 3.3 7.8 0.2 3.1 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGG03843.1 - 0.0098 15.0 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGG03843.1 - 0.019 15.2 3.4 0.78 10.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.1 EGG03843.1 - 0.021 14.4 0.0 0.37 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EGG03843.1 - 0.026 14.2 0.1 3.1 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGG03843.1 - 0.028 14.3 1.5 2.8 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EGG03843.1 - 0.065 12.9 0.0 5.3 6.6 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase SbcCD_C PF13558.1 EGG03843.1 - 0.11 12.4 0.1 2.6 8.0 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EGG03843.1 - 0.13 11.9 0.3 3 7.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 EGG03843.1 - 0.14 11.4 2.7 12 5.0 0.1 3.8 4 0 0 4 4 4 0 PhoH-like protein PRK PF00485.13 EGG03843.1 - 0.3 10.6 0.2 6.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_13 PF13166.1 EGG03843.1 - 0.46 8.8 0.0 94 1.2 0.0 3.2 4 0 0 4 4 4 0 AAA domain Asp PF00026.18 EGG03844.1 - 3.6e-26 92.1 0.0 5.5e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG03844.1 - 9.8e-05 22.3 1.0 0.006 16.5 0.1 3.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EGG03844.1 - 0.028 13.9 0.0 0.054 13.0 0.0 1.5 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Lactonase PF10282.4 EGG03845.1 - 4.8e-59 200.1 0.0 5.9e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF3544 PF12064.3 EGG03845.1 - 0.049 13.4 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3544) Lactonase PF10282.4 EGG03846.1 - 1.4e-56 192.0 0.0 1.7e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HA2 PF04408.18 EGG03848.1 - 9.7e-30 102.6 0.1 2.9e-29 101.0 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGG03848.1 - 1.3e-23 82.9 0.0 3.8e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGG03848.1 - 2.7e-11 43.1 0.0 6.2e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGG03848.1 - 2.4e-08 33.6 0.1 5e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGG03848.1 - 2.2e-05 24.5 0.0 6.3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EGG03848.1 - 0.00025 20.5 0.2 0.00078 18.9 0.2 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 EGG03848.1 - 0.0042 16.8 0.1 0.0083 15.8 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.1 EGG03848.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EGG03848.1 - 0.032 14.0 0.2 0.65 9.7 0.1 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EGG03848.1 - 0.065 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EGG03848.1 - 0.09 11.9 0.0 0.28 10.3 0.0 1.8 1 1 0 1 1 1 0 PhoH-like protein Dioxygenase_C PF00775.16 EGG03849.1 - 1e-53 181.3 0.0 1.5e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EGG03849.1 - 2.7e-17 62.4 0.0 5.5e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EGG03849.1 - 4e-05 23.5 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 EGG03849.1 - 0.0038 17.2 0.0 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4480) Prenyltrans PF00432.16 EGG03850.1 - 6.4e-27 92.7 13.2 1.6e-05 24.3 0.1 5.9 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGG03850.1 - 8.2e-17 61.6 0.0 7.3e-14 52.1 0.0 3.3 2 1 1 3 3 3 3 Prenyltransferase-like DUF605 PF04652.11 EGG03852.1 - 0.28 10.5 10.8 0.27 10.5 7.5 1.0 1 0 0 1 1 1 0 Vta1 like HHH_8 PF14716.1 EGG03854.1 - 0.038 14.1 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF2681 PF10883.3 EGG03856.1 - 0.02 15.1 6.6 0.044 13.9 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Prp19_bind PF06991.6 EGG03856.1 - 0.045 13.0 19.0 0.069 12.4 13.2 1.2 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Nop25 PF09805.4 EGG03856.1 - 0.87 9.6 18.6 0.042 13.9 8.5 1.8 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Trypan_PARP PF05887.6 EGG03856.1 - 3.3 7.5 13.9 2.4 7.9 5.9 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SlyX PF04102.7 EGG03857.1 - 0.08 13.3 2.5 0.24 11.7 1.2 2.3 2 0 0 2 2 2 0 SlyX DUF2413 PF10310.4 EGG03860.1 - 1.5e-64 218.5 11.4 1.5e-64 218.5 7.9 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF2413) ATP-grasp_4 PF13535.1 EGG03863.1 - 2.8e-08 33.7 0.0 5.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGG03863.1 - 9.6e-07 27.8 0.0 1.9e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EGG03863.1 - 0.01 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain MMR_HSR1 PF01926.18 EGG03865.1 - 1.2e-07 31.6 0.5 1.8e-07 31.1 0.3 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGG03865.1 - 0.0028 17.7 0.0 0.015 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain 6PF2K PF01591.13 EGG03865.1 - 0.0058 15.7 0.1 0.017 14.1 0.0 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Miro PF08477.8 EGG03865.1 - 0.0091 16.4 0.3 0.03 14.8 0.1 2.0 1 1 1 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EGG03865.1 - 0.018 14.3 1.0 0.036 13.3 0.7 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.1 EGG03865.1 - 0.025 14.4 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGG03865.1 - 0.025 14.1 0.1 0.037 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGG03865.1 - 0.064 13.2 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EGG03865.1 - 0.074 12.8 0.8 0.14 12.0 0.6 1.8 1 1 0 1 1 1 0 Dynamin family KTI12 PF08433.5 EGG03865.1 - 0.088 12.0 0.2 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ArgK PF03308.11 EGG03865.1 - 0.097 11.4 0.7 0.25 10.0 0.1 1.8 1 1 1 2 2 2 0 ArgK protein cobW PF02492.14 EGG03865.1 - 0.11 11.9 2.4 1.1 8.6 1.6 2.1 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Sas10_Utp3 PF04000.10 EGG03866.1 - 7.4e-07 29.2 0.1 1.9e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Choline_kinase PF01633.15 EGG03867.1 - 1.4e-49 168.5 2.7 6.8e-26 91.1 0.7 3.1 3 0 0 3 3 3 2 Choline/ethanolamine kinase APH PF01636.18 EGG03867.1 - 6.3e-11 42.4 0.0 2.2e-09 37.4 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGG03867.1 - 0.007 15.5 0.1 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase NPR2 PF06218.6 EGG03870.1 - 6.5e-08 31.6 0.0 1.2e-07 30.8 0.0 1.3 1 1 0 1 1 1 1 Nitrogen permease regulator 2 BAP PF06639.6 EGG03871.1 - 0.46 10.2 2.7 0.35 10.5 0.4 1.9 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) Nucleoporin_FG PF13634.1 EGG03874.1 - 8.3e-07 29.2 25.4 1.2e-06 28.7 17.6 1.3 1 0 0 1 1 1 1 Nucleoporin FG repeat region Transket_pyr PF02779.19 EGG03875.1 - 6.6e-46 156.0 0.0 2e-45 154.4 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGG03875.1 - 3.7e-37 127.0 0.2 1.2e-36 125.4 0.2 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aldedh PF00171.17 EGG03877.1 - 3.9e-159 529.9 0.0 4.4e-159 529.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ldh_2 PF02615.9 EGG03877.1 - 0.0018 17.0 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase zf-H2C2_2 PF13465.1 EGG03878.1 - 0.0038 17.4 7.4 0.0038 17.4 5.1 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGG03878.1 - 0.023 15.0 0.9 0.023 15.0 0.6 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG03878.1 - 0.031 14.5 1.1 0.031 14.5 0.7 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Sec63 PF02889.11 EGG03880.1 - 5.7e-84 282.0 0.0 1.4e-83 280.7 0.0 1.6 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.24 EGG03880.1 - 8.3e-36 123.0 0.4 6.7e-28 97.2 0.2 3.2 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EGG03880.1 - 4.7e-08 33.0 0.1 4.2e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGG03880.1 - 4.1e-06 26.5 0.0 1.2e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EGG03880.1 - 0.0046 16.6 0.0 0.62 9.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 EGG03880.1 - 0.0095 16.1 2.9 0.05 13.7 1.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGG03880.1 - 0.017 15.2 0.3 0.08 13.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGG03880.1 - 0.062 12.7 0.1 0.78 9.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Acyl-CoA_dh_1 PF00441.19 EGG03883.1 - 6.2e-35 120.5 0.0 1e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EGG03883.1 - 4e-19 68.2 0.0 8.4e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EGG03883.1 - 3.4e-13 50.1 0.1 2.3e-12 47.5 0.1 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGG03883.1 - 1.3e-11 43.8 0.2 3.1e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGG03883.1 - 0.00071 19.8 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain GN3L_Grn1 PF08701.6 EGG03885.1 - 1.7e-22 79.0 15.0 3.7e-22 78.0 10.4 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EGG03885.1 - 1.5e-17 63.6 0.3 2.1e-14 53.4 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EGG03885.1 - 2.1e-10 40.0 0.1 1.1e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGG03885.1 - 8.9e-05 22.0 0.0 0.0046 16.4 0.0 2.9 1 1 2 3 3 3 1 Elongation factor Tu GTP binding domain cobW PF02492.14 EGG03885.1 - 0.003 17.0 0.1 0.1 12.0 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EGG03885.1 - 0.008 15.3 0.1 0.021 14.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 RGS-like PF09128.6 EGG03885.1 - 0.053 13.0 3.9 0.088 12.2 2.7 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Dynamin_N PF00350.18 EGG03885.1 - 0.63 9.8 7.7 1.1 9.0 0.1 3.5 2 2 1 4 4 4 0 Dynamin family FLO_LFY PF01698.11 EGG03886.1 - 0.13 11.0 2.6 0.14 11.0 1.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3072 PF11272.3 EGG03886.1 - 0.15 11.7 2.2 0.36 10.5 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) Thioredoxin PF00085.15 EGG03887.1 - 5.5e-29 99.9 0.4 6.3e-29 99.7 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 EGG03887.1 - 3.6e-07 29.8 0.1 4.1e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGG03887.1 - 3.7e-07 30.3 0.6 4e-06 26.9 0.4 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGG03887.1 - 9.4e-07 28.8 0.1 4.5e-05 23.4 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 EGG03887.1 - 7.2e-05 22.3 0.2 8.3e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGG03887.1 - 7.3e-05 22.4 0.1 9.2e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EGG03887.1 - 0.00031 20.6 0.0 0.00039 20.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.11 EGG03887.1 - 0.029 13.8 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 TrbC_Ftype PF09673.5 EGG03887.1 - 0.064 12.8 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_6 PF13848.1 EGG03887.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.15 EGG03888.1 - 1.3e-24 85.8 0.1 1.6e-24 85.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGG03888.1 - 1.1e-06 28.6 0.0 0.00011 22.2 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EGG03888.1 - 2.4e-06 27.6 0.0 2.4e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EGG03888.1 - 0.00017 21.2 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGG03888.1 - 0.00018 21.0 0.1 0.0036 16.8 0.0 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 EGG03888.1 - 0.0015 18.1 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin KaiB PF07689.7 EGG03888.1 - 0.07 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 KaiB domain TrbC_Ftype PF09673.5 EGG03888.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_7 PF13899.1 EGG03888.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Beach PF02138.13 EGG03892.1 - 1e-97 326.8 0.0 1.6e-97 326.1 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EGG03892.1 - 2.9e-17 61.7 8.7 6.9e-06 25.7 0.0 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat PH_BEACH PF14844.1 EGG03892.1 - 1e-08 34.9 0.0 2.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 EGG03892.1 - 8.8e-05 22.7 0.0 0.00025 21.2 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily FYVE PF01363.16 EGG03892.1 - 0.0037 17.1 11.1 0.0037 17.1 7.7 2.4 2 0 0 2 2 2 1 FYVE zinc finger CDC27 PF09507.5 EGG03894.1 - 0.026 13.7 12.8 0.033 13.4 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ORC6 PF05460.8 EGG03894.1 - 0.034 13.2 6.4 0.041 12.9 4.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DHHW PF14286.1 EGG03894.1 - 0.063 12.5 1.9 0.076 12.3 1.3 1.1 1 0 0 1 1 1 0 DHHW protein Striatin PF08232.7 EGG03894.1 - 0.067 13.4 2.8 0.1 12.8 2.0 1.4 1 0 0 1 1 1 0 Striatin family PE PF00934.15 EGG03894.1 - 0.076 13.1 0.4 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 PE family Inhibitor_I71 PF12628.2 EGG03894.1 - 0.62 9.7 3.9 0.92 9.1 2.7 1.3 1 1 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Macoilin PF09726.4 EGG03894.1 - 0.66 8.1 6.7 0.76 7.9 4.6 1.1 1 0 0 1 1 1 0 Transmembrane protein MAP65_ASE1 PF03999.7 EGG03894.1 - 1.9 6.9 9.4 2.3 6.7 6.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Presenilin PF01080.12 EGG03894.1 - 2.5 6.8 4.8 3 6.5 3.3 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.5 EGG03894.1 - 6.2 5.1 10.1 7.9 4.7 7.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPRTase PF14681.1 EGG03895.1 - 2.6e-78 261.9 0.0 3.6e-78 261.5 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EGG03895.1 - 0.00047 19.8 0.0 0.00084 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EGG03895.1 - 0.043 13.5 0.6 0.085 12.5 0.2 1.6 2 0 0 2 2 2 0 Influenza C non-structural protein (NS1) CoA_binding_2 PF13380.1 EGG03895.1 - 0.093 12.9 0.0 0.23 11.6 0.0 1.5 2 0 0 2 2 2 0 CoA binding domain zf-primase PF09329.6 EGG03896.1 - 0.00017 21.0 1.2 0.00074 19.0 0.8 2.1 1 1 0 1 1 1 1 Primase zinc finger DUF1423 PF07227.6 EGG03896.1 - 5.7 5.4 8.1 0.5 8.9 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) DUF2892 PF11127.3 EGG03897.1 - 4.5 7.1 5.2 0.61 9.9 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF1627 PF07789.7 EGG03898.1 - 0.056 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) Cu_amine_oxid PF01179.15 EGG03899.1 - 1.8e-151 504.5 0.0 2.2e-151 504.2 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EGG03899.1 - 2.1e-12 46.9 0.0 3.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain OMPdecase PF00215.19 EGG03900.1 - 2.5e-13 49.9 0.3 2.9e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family UBN2 PF14223.1 EGG03902.1 - 6e-05 22.8 0.1 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EGG03902.1 - 7.1e-05 22.4 0.2 0.001 18.6 0.2 2.3 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG03902.1 - 0.00016 21.1 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HTH_19 PF12844.2 EGG03902.1 - 0.14 12.2 0.8 0.47 10.5 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain DUF1900 PF08954.6 EGG03903.1 - 1.2e-47 160.8 0.0 2.4e-47 159.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EGG03903.1 - 1.4e-29 101.5 0.1 2.3e-29 100.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EGG03903.1 - 1.8e-11 43.4 3.6 0.0013 18.4 0.1 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Sec2p PF06428.6 EGG03903.1 - 0.017 14.9 3.6 0.032 14.0 2.5 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF2457 PF10446.4 EGG03905.1 - 0.084 11.5 4.9 0.14 10.8 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF605 PF04652.11 EGG03905.1 - 0.55 9.5 21.0 0.72 9.1 14.5 1.1 1 0 0 1 1 1 0 Vta1 like Herpes_BLLF1 PF05109.8 EGG03905.1 - 3.5 5.4 38.3 5.1 4.9 26.6 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) BCDHK_Adom3 PF10436.4 EGG03907.1 - 1.6e-28 99.3 0.1 2.2e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGG03907.1 - 3.8e-09 36.2 0.0 2.3e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MIP PF00230.15 EGG03911.1 - 9.2e-10 38.3 1.4 1.2e-09 37.9 1.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Colicin_V PF02674.11 EGG03911.1 - 0.028 14.2 5.5 0.072 12.9 3.8 1.7 1 1 0 1 1 1 0 Colicin V production protein DUF1673 PF07895.6 EGG03911.1 - 0.044 13.3 2.3 0.07 12.6 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF4229 PF14012.1 EGG03911.1 - 0.12 12.2 0.7 0.29 11.0 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) AA_permease_2 PF13520.1 EGG03913.1 - 1.1e-53 182.3 48.6 1.5e-53 181.9 33.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGG03913.1 - 1.9e-17 62.8 38.7 2.5e-17 62.3 26.8 1.1 1 0 0 1 1 1 1 Amino acid permease CarbpepA_inh PF02977.10 EGG03913.1 - 0.05 13.1 0.6 0.24 11.0 0.0 2.3 3 0 0 3 3 3 0 Carboxypeptidase A inhibitor NeA_P2 PF12312.3 EGG03914.1 - 0.65 9.1 5.9 0.069 12.3 0.8 1.7 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein Mito_fiss_reg PF05308.6 EGG03914.1 - 2.2 7.6 9.4 0.68 9.2 2.7 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator UcrQ PF02939.11 EGG03915.1 - 4.6e-23 80.8 0.8 5.6e-23 80.5 0.6 1.1 1 0 0 1 1 1 1 UcrQ family Ferrochelatase PF00762.14 EGG03916.1 - 4.4e-103 344.5 0.0 5.1e-103 344.3 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase TIM-br_sig_trns PF09370.5 EGG03916.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 TIM-barrel signal transduction protein Ribosomal_S2 PF00318.15 EGG03918.1 - 0.058 12.6 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S2 Daxx PF03344.10 EGG03918.1 - 0.18 10.2 15.4 0.22 9.9 10.7 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EGG03918.1 - 0.8 7.6 12.9 1.1 7.2 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EGG03918.1 - 0.8 8.9 18.6 1.4 8.1 12.9 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EGG03918.1 - 3.1 5.5 23.1 4.5 5.0 16.0 1.2 1 0 0 1 1 1 0 Nop14-like family Retrotrans_gag PF03732.12 EGG03919.1 - 0.14 12.1 0.0 0.43 10.6 0.0 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein ADH_N PF08240.7 EGG03922.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Ufd2P_core PF10408.4 EGG03924.1 - 3.7e-23 81.6 3.2 3.1e-15 55.4 0.1 2.0 1 1 1 2 2 2 2 Ubiquitin elongating factor core Atg14 PF10186.4 EGG03924.1 - 0.043 12.7 0.6 0.052 12.4 0.4 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATP_sub_h PF10775.4 EGG03927.1 - 0.53 10.0 4.0 0.59 9.8 0.0 2.6 2 0 0 2 2 2 0 ATP synthase complex subunit h ORC5_C PF14630.1 EGG03929.1 - 7e-44 150.3 0.0 4.2e-32 111.6 0.0 2.3 2 0 0 2 2 2 2 Origin recognition complex (ORC) subunit 5 C-terminus RA PF00788.18 EGG03930.1 - 2.9e-09 37.2 0.0 2.8e-08 34.1 0.0 2.6 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 EGG03930.1 - 4.7e-06 25.8 0.0 1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGG03930.1 - 0.0012 18.3 0.0 0.0024 17.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Calcipressin PF04847.7 EGG03931.1 - 1.8e-27 96.1 0.2 6.3e-22 78.0 0.3 2.4 2 0 0 2 2 2 2 Calcipressin ADH_N PF08240.7 EGG03932.1 - 1.5e-21 76.1 3.6 1.5e-21 76.1 2.5 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGG03932.1 - 1.4e-16 60.2 0.8 2.4e-16 59.4 0.5 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGG03932.1 - 0.015 14.4 0.1 0.031 13.4 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 EGG03932.1 - 0.017 15.0 1.2 0.036 14.0 0.8 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus UDPG_MGDP_dh_N PF03721.9 EGG03932.1 - 0.048 13.0 0.1 0.079 12.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PQQ PF01011.16 EGG03932.1 - 0.055 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat CDP-OH_P_transf PF01066.16 EGG03933.1 - 5e-10 39.5 0.0 5e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Na_Ca_ex PF01699.19 EGG03937.1 - 1.3e-47 160.9 35.2 9.2e-26 90.1 6.5 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF3129 PF11327.3 EGG03938.1 - 0.052 13.3 0.2 0.084 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3129) DUF605 PF04652.11 EGG03939.1 - 9.7e-77 258.9 3.8 1.2e-76 258.6 2.7 1.1 1 0 0 1 1 1 1 Vta1 like ESR1_C PF12743.2 EGG03939.1 - 3.7 7.1 7.5 9.2 5.8 0.9 3.0 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal Cpn60_TCP1 PF00118.19 EGG03940.1 - 6.9e-146 486.6 1.3 7.8e-146 486.4 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_12 PF01670.11 EGG03941.1 - 3.5e-21 75.5 0.0 7.3e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Peptidase_S29 PF02907.10 EGG03941.1 - 0.081 12.4 0.2 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease DUF4393 PF14337.1 EGG03942.1 - 0.053 12.9 0.2 1 8.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) Orthopox_A5L PF06193.6 EGG03943.1 - 0.0042 17.0 0.3 0.0071 16.2 0.2 1.4 1 0 0 1 1 1 1 Orthopoxvirus A5L protein-like CCDC-167 PF15188.1 EGG03943.1 - 0.033 14.1 0.2 0.078 12.9 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 EcoEI_R_C PF08463.5 EGG03943.1 - 0.033 14.0 0.4 0.068 13.0 0.3 1.6 1 0 0 1 1 1 0 EcoEI R protein C-terminal Glypican PF01153.14 EGG03945.1 - 4.4 5.7 6.7 8 4.9 4.6 1.4 1 0 0 1 1 1 0 Glypican DUF3824 PF12868.2 EGG03948.1 - 0.59 11.0 5.8 0.14 13.0 1.3 1.8 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) CAF-1_p150 PF11600.3 EGG03950.1 - 0.0032 16.8 13.4 0.0038 16.6 9.3 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MxiH PF09392.5 EGG03950.1 - 0.096 13.2 3.1 0.16 12.5 2.2 1.5 1 1 0 1 1 1 0 Type III secretion needle MxiH like DUF3292 PF11696.3 EGG03950.1 - 2.5 5.8 10.5 3.1 5.5 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) YgaB PF14182.1 EGG03950.1 - 4.7 7.5 9.1 0.16 12.2 1.6 1.9 2 0 0 2 2 2 0 YgaB-like protein MFS_1 PF07690.11 EGG03952.1 - 3.4e-43 147.6 41.9 4e-41 140.9 29.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGG03952.1 - 8.5e-07 27.5 23.1 5.9e-06 24.7 16.0 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGG03952.1 - 1.3e-06 27.2 12.4 1.3e-06 27.2 8.6 3.4 4 1 0 4 4 4 2 Sugar (and other) transporter GTP_EFTU PF00009.22 EGG03955.1 - 4.2e-34 117.6 0.0 1.1e-33 116.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGG03955.1 - 1.9e-18 66.3 0.0 5.6e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EGG03955.1 - 8.1e-13 48.2 10.4 5.4e-10 39.2 0.1 3.8 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGG03955.1 - 8.9e-07 28.8 0.1 3e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Nop14 PF04147.7 EGG03955.1 - 0.0018 16.2 38.6 0.0031 15.5 26.8 1.3 1 0 0 1 1 1 1 Nop14-like family Miro PF08477.8 EGG03955.1 - 0.0031 17.9 0.8 0.013 16.0 0.0 2.5 2 0 0 2 2 1 1 Miro-like protein ATP_bind_1 PF03029.12 EGG03955.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Ras PF00071.17 EGG03955.1 - 0.031 13.6 0.0 0.11 11.8 0.0 2.0 1 1 0 1 1 1 0 Ras family AAA_22 PF13401.1 EGG03955.1 - 0.05 13.7 0.2 0.31 11.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain GTP_EFTU_D4 PF14578.1 EGG03955.1 - 0.13 11.8 2.0 0.18 11.4 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 4 AAA_16 PF13191.1 EGG03955.1 - 0.18 11.7 3.4 0.52 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain TFIIA PF03153.8 EGG03955.1 - 1.4 8.7 26.6 2.6 7.8 18.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ARGLU PF15346.1 EGG03955.1 - 2.3 8.0 36.8 0.69 9.6 16.0 2.6 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 YL1 PF05764.8 EGG03955.1 - 8.3 5.9 42.7 2.3 7.7 14.4 2.5 2 0 0 2 2 2 0 YL1 nuclear protein MGAT2 PF05060.9 EGG03959.1 - 0.0041 16.0 1.0 0.0041 16.0 0.7 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) Abhydrolase_5 PF12695.2 EGG03960.1 - 9.9e-21 74.0 0.0 1.5e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG03960.1 - 2.5e-14 53.7 0.0 5.1e-13 49.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG03960.1 - 9.3e-09 35.1 0.0 2e-06 27.5 0.0 1.9 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 EGG03960.1 - 0.00022 20.7 0.0 0.00044 19.7 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EGG03960.1 - 0.0012 18.1 0.0 0.0044 16.2 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 EGG03960.1 - 0.0015 17.1 0.0 0.037 12.5 0.0 2.2 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 EGG03960.1 - 0.0041 16.8 0.0 0.081 12.6 0.0 2.2 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EGG03960.1 - 0.01 15.2 0.1 2.1 7.7 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EGG03960.1 - 0.022 14.3 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 EGG03960.1 - 0.11 11.7 0.0 0.73 9.0 0.0 2.2 2 1 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S10 PF00450.17 EGG03960.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase Lipase_3 PF01764.20 EGG03960.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) SNF2_N PF00176.18 EGG03963.1 - 5.2e-37 127.2 0.4 5.8e-37 127.1 0.3 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGG03963.1 - 2.4e-06 27.1 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGG03963.1 - 0.087 12.6 0.0 0.11 12.3 0.0 1.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGG03964.1 - 2.2e-13 49.8 0.0 4.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1137 PF06587.6 EGG03966.1 - 0.034 13.8 0.1 0.037 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1137) ERGIC_N PF13850.1 EGG03966.1 - 0.18 11.7 0.5 0.22 11.5 0.4 1.1 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pox_A12 PF04651.8 EGG03967.1 - 0.083 13.0 1.2 0.1 12.7 0.8 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein DUF2217 PF10265.4 EGG03967.1 - 0.53 8.9 3.4 0.59 8.8 2.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SR-25 PF10500.4 EGG03968.1 - 0.73 9.2 21.6 0.039 13.4 8.5 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FDF PF09532.5 EGG03968.1 - 1.3 9.6 12.5 5.8 7.5 0.1 2.9 1 1 1 2 2 2 0 FDF domain TraV PF09676.5 EGG03968.1 - 9.2 6.9 11.7 5.1 7.8 2.1 2.4 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) NuA4 PF09340.5 EGG03969.1 - 1.1e-16 60.2 3.4 2.2e-16 59.2 0.2 2.5 2 1 0 2 2 2 1 Histone acetyltransferase subunit NuA4 CotH PF08757.6 EGG03969.1 - 0.026 13.7 0.2 0.036 13.3 0.2 1.2 1 0 0 1 1 1 0 CotH protein STAT6_C PF14596.1 EGG03969.1 - 0.066 13.1 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 STAT6 C-terminal VP_N-CPKC PF11475.3 EGG03969.1 - 0.18 11.3 0.4 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 Virion protein N terminal domain DnaI_N PF07319.6 EGG03969.1 - 0.23 11.7 5.1 0.12 12.6 1.9 1.7 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus TMPIT PF07851.8 EGG03969.1 - 0.98 8.4 5.6 0.16 10.9 1.5 1.4 2 0 0 2 2 2 0 TMPIT-like protein Prefoldin_2 PF01920.15 EGG03969.1 - 7.2 6.4 13.1 0.54 10.0 2.6 2.3 2 0 0 2 2 2 0 Prefoldin subunit Asp PF00026.18 EGG03971.1 - 9.2e-69 232.1 6.2 1.3e-68 231.6 4.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG03971.1 - 0.00011 22.2 0.0 0.001 19.0 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EGG03971.1 - 0.0042 16.6 0.2 0.03 13.8 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal HLH PF00010.21 EGG03972.1 - 7.1e-12 44.8 0.0 1.6e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DNA_methylase PF00145.12 EGG03972.1 - 0.59 9.2 7.5 0.091 11.8 2.2 1.7 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase MGAT2 PF05060.9 EGG03973.1 - 0.0052 15.7 0.9 0.0052 15.7 0.6 1.1 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) UCH_1 PF13423.1 EGG03974.1 - 4.5e-44 151.0 0.0 7.1e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EGG03974.1 - 8.7e-25 87.9 0.0 2.2e-24 86.5 0.0 1.7 2 0 0 2 2 2 1 Exonuclease UCH PF00443.24 EGG03974.1 - 2.7e-06 26.6 0.0 6.6e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DZR PF12773.2 EGG03974.1 - 0.38 10.5 4.8 3.5 7.5 3.4 2.3 1 1 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 EGG03974.1 - 1.8 8.2 4.2 13 5.5 0.1 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain WT1 PF02165.10 EGG03975.1 - 0.017 14.1 0.4 0.029 13.4 0.3 1.3 1 0 0 1 1 1 0 Wilm's tumour protein RasGAP_C PF03836.10 EGG03975.1 - 0.02 14.6 0.9 0.035 13.7 0.6 1.4 1 0 0 1 1 1 0 RasGAP C-terminus RP-C_C PF11800.3 EGG03975.1 - 0.075 12.7 1.3 0.14 11.8 0.7 1.5 2 0 0 2 2 2 0 Replication protein C C-terminal region MFS_1 PF07690.11 EGG03985.1 - 9.9e-41 139.6 45.7 4.7e-39 134.0 30.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG03985.1 - 1.3e-06 27.2 15.2 1.3e-06 27.2 10.5 3.5 3 1 0 3 3 3 2 Sugar (and other) transporter SNO PF01174.14 EGG03987.1 - 2.2e-44 151.3 0.0 3e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EGG03987.1 - 9.4e-07 28.5 0.0 1.3e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_5 PF13507.1 EGG03987.1 - 0.081 11.8 0.0 0.41 9.5 0.0 1.8 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain CsbD PF05532.7 EGG03988.1 - 0.6 9.8 5.2 0.11 12.1 0.9 1.8 2 0 0 2 2 2 0 CsbD-like EcoEI_R_C PF08463.5 EGG03991.1 - 0.039 13.8 0.5 0.065 13.0 0.3 1.3 1 0 0 1 1 1 0 EcoEI R protein C-terminal Baculo_PEP_C PF04513.7 EGG03992.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 EGG03992.1 - 0.015 13.8 0.6 0.015 13.8 0.4 1.6 2 0 0 2 2 2 0 AAA domain Troponin PF00992.15 EGG03992.1 - 0.023 14.7 0.2 0.023 14.7 0.1 1.8 2 0 0 2 2 2 0 Troponin APP_E2 PF12925.2 EGG03992.1 - 0.038 13.5 0.9 0.074 12.6 0.6 1.4 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein DivIVA PF05103.8 EGG03992.1 - 0.045 13.7 0.2 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 DivIVA protein DUF4200 PF13863.1 EGG03992.1 - 0.27 11.1 4.9 0.23 11.4 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.7 EGG03993.1 - 0.017 14.9 0.5 0.032 14.0 0.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.7 EGG03993.1 - 0.019 15.3 0.6 0.064 13.6 0.4 1.9 1 0 0 1 1 1 0 SlyX ATG16 PF08614.6 EGG03993.1 - 0.019 14.7 0.6 0.019 14.7 0.4 2.5 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF2383 PF09537.5 EGG03993.1 - 0.075 13.2 0.3 0.22 11.8 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) DivIC PF04977.10 EGG03993.1 - 1.9 8.0 5.2 0.21 11.0 0.4 1.7 2 0 0 2 2 2 0 Septum formation initiator TFIIA PF03153.8 EGG03994.1 - 0.00086 19.3 15.9 0.00086 19.3 11.0 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF2612 PF11041.3 EGG03996.1 - 4.8e-05 23.0 0.0 1 8.9 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2612) DUF3610 PF12272.3 EGG03996.1 - 0.00053 19.6 3.8 2.3 7.8 0.0 3.5 4 0 0 4 4 4 3 Protein of unknown function (DUF3610) MGC-24 PF05283.6 EGG03996.1 - 0.0057 16.4 13.6 0.0057 16.4 9.4 7.0 4 1 2 6 6 6 2 Multi-glycosylated core protein 24 (MGC-24) PuR_N PF09182.5 EGG03996.1 - 0.069 12.7 1.8 15 5.2 0.0 3.0 3 0 0 3 3 3 0 Bacterial purine repressor, N-terminal Phage_BR0599 PF09356.5 EGG03996.1 - 0.26 11.4 8.2 16 5.7 0.0 4.0 4 0 0 4 4 4 0 Phage conserved hypothetical protein BR0599 NAD_binding_8 PF13450.1 EGG03999.1 - 3.2e-13 49.5 0.0 6.5e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGG03999.1 - 6e-05 22.1 0.2 8.4e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EGG03999.1 - 0.00045 19.4 0.0 0.00054 19.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EGG03999.1 - 0.001 19.1 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGG03999.1 - 0.0091 15.7 0.0 0.017 14.8 0.0 1.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGG03999.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGG03999.1 - 0.073 11.5 0.1 0.11 10.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 EGG03999.1 - 0.079 11.7 0.2 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EGG03999.1 - 0.089 13.2 0.2 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGG03999.1 - 0.15 11.1 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family WD40 PF00400.27 EGG04001.1 - 5.2e-22 76.8 4.7 2.2e-06 27.3 0.0 7.5 6 2 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EGG04001.1 - 0.08 11.0 0.0 1.1 7.2 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DHHA2 PF02833.9 EGG04007.1 - 0.021 14.9 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 DHHA2 domain Colicin_Pyocin PF01320.13 EGG04007.1 - 0.17 11.7 1.3 0.34 10.7 0.1 1.9 2 0 0 2 2 2 0 Colicin immunity protein / pyocin immunity protein zf-CCHC_4 PF14392.1 EGG04009.1 - 0.089 12.4 2.2 0.18 11.4 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EGG04009.1 - 0.18 11.7 2.1 0.31 11.0 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Ufd2P_core PF10408.4 EGG04010.1 - 3.9e-11 41.9 0.1 7.2e-11 41.0 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin elongating factor core DUF1757 PF08560.5 EGG04010.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) Alpha_kinase PF02816.13 EGG04011.1 - 1.4e-14 54.1 0.2 1.4e-14 54.1 0.1 1.4 2 0 0 2 2 2 1 Alpha-kinase family Helicase_C PF00271.26 EGG04012.1 - 5e-09 35.9 0.0 7.4e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain XRN_N PF03159.13 EGG04014.1 - 4e-92 307.9 0.0 4.6e-92 307.7 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus GMP_synt_C PF00958.17 EGG04016.1 - 2.4e-39 132.9 0.1 5.2e-39 131.8 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EGG04016.1 - 6.1e-39 133.4 0.0 1.2e-38 132.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGG04016.1 - 1.1e-11 44.5 0.0 2.3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 EGG04016.1 - 1.9e-11 43.3 0.2 3.6e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.11 EGG04016.1 - 0.00047 18.8 0.1 0.00084 17.9 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 EGG04016.1 - 0.00063 19.2 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EGG04016.1 - 0.0031 17.0 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.14 EGG04016.1 - 0.0086 15.1 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase DUF2392 PF10288.4 EGG04016.1 - 0.019 15.2 0.0 0.055 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) QueC PF06508.8 EGG04016.1 - 0.022 14.0 0.0 0.069 12.4 0.0 1.8 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.14 EGG04016.1 - 0.026 14.3 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 EGG04016.1 - 0.032 13.7 0.2 0.074 12.5 0.0 1.7 2 0 0 2 2 2 0 PP-loop family WD40 PF00400.27 EGG04019.1 - 0.014 15.3 0.6 0.025 14.4 0.0 1.8 2 1 0 2 2 2 0 WD domain, G-beta repeat PhosphMutase PF10143.4 EGG04019.1 - 0.084 12.5 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase DUF2644 PF10841.3 EGG04020.1 - 0.15 12.0 0.7 0.26 11.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) tRNA-synt_1 PF00133.17 EGG04021.1 - 7.9e-42 143.0 0.0 1.6e-29 102.4 0.0 4.4 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EGG04021.1 - 1.3e-16 60.2 0.0 1.6e-08 33.6 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGG04021.1 - 3.8e-13 49.4 0.0 8.9e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGG04021.1 - 5.9e-10 38.7 0.0 1.7e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain 3HCDH_N PF02737.13 EGG04022.1 - 5.9e-53 179.1 6.4 1.9e-52 177.5 4.4 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EGG04022.1 - 6e-35 119.5 0.2 1.6e-34 118.1 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EGG04022.1 - 8.8e-08 32.0 0.5 1.5e-07 31.2 0.3 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EGG04022.1 - 0.0024 17.7 2.5 0.0088 15.8 1.8 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 EGG04022.1 - 0.016 14.1 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ELFV_dehydrog PF00208.16 EGG04022.1 - 0.021 14.3 0.5 0.038 13.5 0.4 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DXP_synthase_N PF13292.1 EGG04022.1 - 0.035 13.0 0.8 0.051 12.4 0.3 1.4 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase ApbA PF02558.11 EGG04022.1 - 0.046 13.1 0.3 0.11 11.9 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Methyltransf_12 PF08242.7 EGG04022.1 - 0.058 13.8 0.4 16 6.0 0.1 2.5 1 1 1 2 2 2 0 Methyltransferase domain F420_oxidored PF03807.12 EGG04022.1 - 0.12 12.7 4.7 0.5 10.8 3.1 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DnaJ PF00226.26 EGG04023.1 - 1.2e-22 79.3 1.2 5.2e-21 74.1 0.4 2.9 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.1 EGG04023.1 - 1.3e-19 70.3 8.3 0.00086 19.5 0.1 6.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGG04023.1 - 9.3e-19 66.8 6.2 2.2e-05 23.9 0.1 5.1 3 2 3 6 6 6 4 TPR repeat TPR_2 PF07719.12 EGG04023.1 - 4.9e-18 63.5 1.8 0.047 13.6 0.0 7.6 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGG04023.1 - 5.6e-18 65.1 0.0 2.3e-05 24.9 0.0 4.6 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGG04023.1 - 7.5e-14 50.6 0.6 0.095 12.3 0.0 6.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGG04023.1 - 7e-13 47.9 4.3 0.03 14.9 0.0 6.7 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGG04023.1 - 5.5e-08 32.5 0.5 0.037 13.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG04023.1 - 7e-08 32.3 3.2 0.018 14.9 0.2 4.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGG04023.1 - 8.3e-08 31.8 0.9 3.1 8.2 0.1 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EGG04023.1 - 2.4e-06 27.5 12.1 0.0019 18.3 0.3 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EGG04023.1 - 4.8e-06 26.5 2.5 0.049 13.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGG04023.1 - 6.7e-06 25.5 2.4 1 9.2 0.0 5.4 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGG04023.1 - 3.4e-05 24.0 0.6 52 4.6 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EGG04023.1 - 0.0068 15.6 1.0 3.6 6.7 0.0 2.8 2 1 0 2 2 2 2 Coatomer epsilon subunit TPR_7 PF13176.1 EGG04023.1 - 0.018 14.8 3.2 18 5.4 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGG04023.1 - 0.02 15.2 0.0 8.6 7.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat YfiO PF13525.1 EGG04023.1 - 0.027 13.9 0.5 1.1 8.6 0.1 3.4 3 1 1 4 4 4 0 Outer membrane lipoprotein YfdX PF10938.3 EGG04023.1 - 0.23 11.1 11.0 2.4 7.8 1.7 4.0 3 1 1 4 4 4 0 YfdX protein Acyl_transf_3 PF01757.17 EGG04024.1 - 3.9e-26 91.7 27.5 5.2e-26 91.2 19.1 1.2 1 0 0 1 1 1 1 Acyltransferase family Histidinol_dh PF00815.15 EGG04025.1 - 9.8e-163 541.5 0.0 1.3e-162 541.2 0.0 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EGG04025.1 - 2.9e-28 97.3 0.1 5.3e-28 96.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EGG04025.1 - 5.3e-10 39.4 0.0 1.3e-08 35.0 0.0 3.0 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EGG04025.1 - 0.00013 21.8 0.8 0.00024 20.9 0.6 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain AAA_26 PF13500.1 EGG04025.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EGG04026.1 - 9.7e-28 96.8 0.9 1.8e-27 95.8 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EGG04026.1 - 1.7e-09 37.8 6.8 5.2e-07 29.7 3.2 2.5 1 1 1 2 2 2 2 DNA-binding domain PHD_2 PF13831.1 EGG04027.1 - 0.021 14.1 0.7 0.12 11.7 0.5 2.3 1 0 0 1 1 1 0 PHD-finger PXA PF02194.10 EGG04029.1 - 5.6e-29 101.0 0.4 1.3e-28 99.8 0.3 1.6 1 0 0 1 1 1 1 PXA domain TCR_zetazeta PF11628.3 EGG04029.1 - 0.099 12.1 3.7 0.081 12.3 0.8 2.1 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain zf-ZPR1 PF03367.8 EGG04030.1 - 7.1e-07 28.5 0.0 9.5e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 ZPR1 zinc-finger domain DUF3295 PF11702.3 EGG04031.1 - 6.7e-09 35.2 18.4 6.7e-09 35.2 12.8 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3295) CAF1A PF12253.3 EGG04031.1 - 0.00059 19.8 2.6 0.0014 18.6 1.8 1.5 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A CAF1-p150_C2 PF15539.1 EGG04031.1 - 0.11 11.5 0.1 0.11 11.5 0.1 1.6 2 0 0 2 2 2 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term NOA36 PF06524.7 EGG04031.1 - 0.96 8.6 3.3 1.6 7.9 2.3 1.2 1 0 0 1 1 1 0 NOA36 protein Senescence_reg PF04520.8 EGG04031.1 - 3.6 8.0 9.1 13 6.2 6.3 2.0 1 1 0 1 1 1 0 Senescence regulator HTH_Tnp_4 PF13613.1 EGG04032.1 - 0.0045 16.4 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease SPT2 PF08243.6 EGG04034.1 - 3.1e-08 33.9 9.6 3.6e-08 33.7 6.6 1.1 1 0 0 1 1 1 1 SPT2 chromatin protein Acyl-CoA_dh_1 PF00441.19 EGG04035.1 - 4.1e-48 163.3 1.3 5.7e-48 162.8 0.5 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGG04035.1 - 3.7e-26 91.9 0.0 8.4e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGG04035.1 - 1.4e-20 73.9 0.0 2e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGG04035.1 - 1.8e-18 65.7 0.0 3.4e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Ni_hydr_CYTB PF01292.15 EGG04039.1 - 0.1 11.9 0.0 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 DUF1310 PF07006.6 EGG04039.1 - 0.15 11.5 2.7 0.6 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1310) DUF3232 PF11554.3 EGG04043.1 - 0.067 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) RAP1 PF07218.6 EGG04043.1 - 2.8 5.9 15.9 4.7 5.1 11.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-RING_2 PF13639.1 EGG04044.1 - 2e-07 30.7 4.2 4.4e-07 29.6 2.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGG04044.1 - 0.00048 19.7 1.3 0.0018 17.9 1.0 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGG04044.1 - 0.0094 15.5 2.9 0.044 13.4 2.1 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG04044.1 - 0.045 13.4 2.1 0.13 11.9 1.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG04044.1 - 0.13 12.3 3.8 0.49 10.4 2.7 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EGG04044.1 - 0.24 11.1 2.2 0.6 9.8 1.6 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.1 EGG04046.1 - 0.035 13.9 12.3 0.035 13.9 8.5 2.0 2 1 0 2 2 2 0 Ring finger domain zf-RING_2 PF13639.1 EGG04047.1 - 1e-07 31.6 4.2 1.9e-07 30.7 2.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGG04047.1 - 0.00049 19.7 2.0 0.0012 18.5 1.4 1.6 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGG04047.1 - 0.0067 16.0 3.2 0.023 14.3 2.3 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG04047.1 - 0.028 14.4 2.0 0.06 13.3 1.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG04047.1 - 0.033 13.8 2.2 0.06 13.0 1.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) gp32 PF08804.5 EGG04047.1 - 0.13 12.3 0.0 2.2 8.4 0.0 2.2 2 0 0 2 2 2 0 gp32 DNA binding protein like PHD PF00628.24 EGG04047.1 - 0.14 11.8 2.2 0.26 10.9 1.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 EGG04047.1 - 0.2 11.5 1.4 0.44 10.4 1.0 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGG04047.1 - 0.22 11.4 1.8 1.9 8.3 1.4 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGG04047.1 - 0.32 11.1 3.7 0.66 10.1 2.5 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EGG04047.1 - 0.34 10.5 2.3 0.82 9.3 1.5 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_3 PF14369.1 EGG04047.1 - 0.4 10.7 2.8 2.7 8.0 0.2 2.4 2 0 0 2 2 2 0 zinc-finger Endonuclease_7 PF02945.10 EGG04047.1 - 0.45 10.2 1.9 0.75 9.5 1.3 1.3 1 0 0 1 1 1 0 Recombination endonuclease VII RINGv PF12906.2 EGG04047.1 - 2.9 7.9 5.3 6.9 6.8 3.1 2.0 1 1 1 2 2 2 0 RING-variant domain DUF2838 PF10998.3 EGG04048.1 - 4.6e-35 119.8 8.1 4.6e-35 119.8 5.6 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) UCH PF00443.24 EGG04050.1 - 1.8e-55 187.9 0.2 2.7e-55 187.3 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGG04050.1 - 2e-23 83.2 0.5 4e-23 82.2 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Yeast-kill-tox PF09207.6 EGG04051.1 - 0.78 10.2 4.8 3 8.3 1.6 2.3 2 1 0 2 2 2 0 Yeast killer toxin RsbU_N PF08673.5 EGG04052.1 - 0.043 13.8 0.7 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain PPR_3 PF13812.1 EGG04052.1 - 0.15 12.4 0.2 6.2 7.3 0.1 3.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain DnaJ PF00226.26 EGG04054.1 - 7.4e-07 28.8 0.0 1.8e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain HSCB_C PF07743.8 EGG04054.1 - 1.8e-06 28.2 4.1 0.00017 21.9 0.3 2.5 2 0 0 2 2 2 2 HSCB C-terminal oligomerisation domain Ogr_Delta PF04606.7 EGG04054.1 - 0.0088 15.6 2.7 0.015 14.9 1.9 1.4 1 0 0 1 1 1 1 Ogr/Delta-like zinc finger RNHCP PF12647.2 EGG04054.1 - 0.051 13.4 0.2 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 RNHCP domain Zn-ribbon_8 PF09723.5 EGG04054.1 - 0.081 12.8 1.4 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.14 EGG04054.1 - 0.11 12.1 0.6 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DNA_RNApol_7kD PF03604.8 EGG04054.1 - 0.22 11.0 1.2 0.42 10.1 0.1 1.9 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.1 EGG04054.1 - 4.1 6.7 5.0 15 4.9 3.6 1.8 1 1 0 1 1 1 0 zinc-ribbon domain Aldedh PF00171.17 EGG04055.1 - 1.3e-72 244.6 0.0 1.8e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ubiquitin_3 PF14836.1 EGG04055.1 - 0.15 11.7 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Phage_min_cap2 PF06152.6 EGG04055.1 - 0.16 10.9 0.2 0.24 10.3 0.2 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 COesterase PF00135.23 EGG04057.1 - 1.1e-79 268.5 0.0 1.6e-79 268.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family PC-Esterase PF13839.1 EGG04058.1 - 1.3e-08 34.9 1.4 2.3e-08 34.1 1.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p CDC45 PF02724.9 EGG04059.1 - 0.47 8.4 5.6 0.51 8.3 3.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Mucin PF01456.12 EGG04059.1 - 9.1 6.0 11.5 16 5.2 8.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Git3 PF11710.3 EGG04060.1 - 3e-10 39.9 12.2 2.6e-09 36.9 8.4 2.0 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EGG04060.1 - 3.5e-05 23.4 0.0 0.0001 21.9 0.0 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EGG04060.1 - 0.00021 20.5 5.2 0.00027 20.1 3.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EGG04060.1 - 0.2 10.5 10.6 0.58 8.9 7.3 1.7 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor DUF2534 PF10749.4 EGG04060.1 - 0.81 9.6 4.0 0.62 10.0 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) Alpha_kinase PF02816.13 EGG04061.1 - 2.2e-05 24.1 0.2 3.6e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Alpha-kinase family zf-C2H2 PF00096.21 EGG04064.1 - 5.4e-06 26.4 8.1 0.0027 17.9 1.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG04064.1 - 0.0002 21.4 7.4 0.00096 19.3 1.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGG04064.1 - 0.0034 17.6 4.0 0.72 10.2 0.5 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.7 EGG04064.1 - 0.075 13.1 0.3 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EGG04064.1 - 0.083 13.0 0.7 0.083 13.0 0.5 2.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 EGG04064.1 - 0.084 12.8 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 zinc-finger ABG_transport PF03806.8 EGG04065.1 - 0.12 10.3 0.0 0.13 10.2 0.0 1.0 1 0 0 1 1 1 0 AbgT putative transporter family P22_AR_C PF10548.4 EGG04067.1 - 0.025 14.4 0.2 0.15 11.9 0.1 2.2 2 0 0 2 2 2 0 P22AR C-terminal domain Tyrosinase PF00264.15 EGG04068.1 - 1.4e-31 110.3 1.0 1.4e-31 110.3 0.7 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase ORF6C PF10552.4 EGG04070.1 - 0.068 12.9 0.1 0.096 12.4 0.1 1.3 1 0 0 1 1 1 0 ORF6C domain Ly49 PF08391.5 EGG04070.1 - 0.11 12.6 0.4 0.13 12.4 0.3 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Hexokinase_1 PF00349.16 EGG04070.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Hexokinase Seryl_tRNA_N PF02403.17 EGG04070.1 - 0.13 12.2 2.3 0.2 11.6 1.6 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Toxin_39 PF15500.1 EGG04070.1 - 0.21 11.7 1.6 0.24 11.5 0.7 1.5 1 1 1 2 2 2 0 Putative RNase-like toxin LSM PF01423.17 EGG04073.1 - 4.1e-18 64.6 0.4 5.2e-18 64.3 0.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGG04073.1 - 1.2e-06 28.3 0.1 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Proteasome PF00227.21 EGG04075.1 - 1.2e-59 200.7 0.0 1.9e-59 200.1 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 EGG04075.1 - 3.1e-10 39.1 0.2 7.5e-10 37.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature WD40 PF00400.27 EGG04076.1 - 1.8e-18 65.6 22.4 3e-05 23.7 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Pec_lyase_C PF00544.14 EGG04077.1 - 2.4e-19 69.5 5.3 6e-19 68.3 3.7 1.6 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EGG04077.1 - 0.00017 21.3 7.0 0.00033 20.4 4.9 1.6 1 1 0 1 1 1 1 Right handed beta helix region AMMECR1 PF01871.12 EGG04078.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 AMMECR1 Actin PF00022.14 EGG04080.1 - 3.5e-45 154.0 0.0 8.3e-44 149.5 0.0 2.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGG04080.1 - 0.16 10.5 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein DASH_Dad4 PF08650.5 EGG04081.1 - 2.4e-13 49.7 5.3 2.5e-13 49.6 3.7 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 FUSC-like PF12805.2 EGG04081.1 - 0.024 13.5 0.4 0.023 13.6 0.3 1.0 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF1220 PF06758.8 EGG04081.1 - 0.031 14.0 0.3 0.04 13.7 0.2 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1220) DASH_Dad1 PF08649.5 EGG04081.1 - 0.13 12.0 0.9 0.15 11.7 0.4 1.4 1 1 0 1 1 1 0 DASH complex subunit Dad1 TPR_11 PF13414.1 EGG04081.1 - 0.16 11.6 1.0 5.5 6.7 0.1 2.1 1 1 1 2 2 2 0 TPR repeat Histone PF00125.19 EGG04082.1 - 5.4e-31 106.5 0.4 8.6e-31 105.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGG04082.1 - 7.9e-05 22.7 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGG04082.1 - 0.004 17.1 0.1 0.004 17.1 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PRAI PF00697.17 EGG04082.1 - 0.053 13.0 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Bromo_TP PF07524.8 EGG04082.1 - 0.056 13.1 0.1 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 EGG04082.1 - 0.13 12.0 0.2 0.23 11.2 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit zf-Tim10_DDP PF02953.10 EGG04083.1 - 7.9e-19 66.7 4.3 7.9e-19 66.7 3.0 1.5 2 0 0 2 2 2 1 Tim10/DDP family zinc finger Insulin PF00049.13 EGG04083.1 - 0.23 12.2 0.3 0.23 12.2 0.2 2.2 1 1 1 2 2 2 0 Insulin/IGF/Relaxin family Ribosomal_L19 PF01245.15 EGG04084.1 - 4.2e-20 71.6 0.3 5.8e-20 71.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 Endonuc-BglII PF09195.6 EGG04084.1 - 0.037 13.4 0.3 2.2 7.7 0.0 2.1 2 0 0 2 2 2 0 Restriction endonuclease BglII N_Asn_amidohyd PF14736.1 EGG04084.1 - 0.11 11.3 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase UL73_N PF12522.3 EGG04084.1 - 0.14 11.6 1.2 0.26 10.8 0.9 1.4 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal NUC153 PF08159.7 EGG04088.1 - 6.2e-10 38.4 2.0 1.1e-09 37.6 1.4 1.5 1 0 0 1 1 1 1 NUC153 domain DASH_Duo1 PF08651.5 EGG04090.1 - 1.1e-11 44.1 0.3 1.1e-11 44.1 0.2 1.9 2 0 0 2 2 2 1 DASH complex subunit Duo1 Herpes_env PF01673.13 EGG04090.1 - 0.27 9.7 2.9 0.33 9.4 2.0 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein adh_short_C2 PF13561.1 EGG04091.1 - 2.3e-30 106.1 0.0 2.7e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGG04091.1 - 4.1e-29 101.6 0.0 5.5e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG04091.1 - 2.8e-09 36.9 0.0 3.7e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EGG04091.1 - 0.0015 18.3 0.0 0.0037 17.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cutinase PF01083.17 EGG04092.1 - 3.1e-30 105.2 3.0 3.6e-30 105.0 2.1 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EGG04092.1 - 1.4e-05 24.6 0.1 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EGG04092.1 - 0.0033 17.2 0.0 0.0049 16.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_1 PF00561.15 EGG04092.1 - 0.0064 16.0 0.0 0.0077 15.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG04092.1 - 0.0072 16.0 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGG04092.1 - 0.02 15.1 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.2 EGG04092.1 - 0.077 12.8 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EGG04092.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cutinase PF01083.17 EGG04093.1 - 1.8e-29 102.7 3.6 2.1e-29 102.5 2.5 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EGG04093.1 - 8.4e-06 25.3 0.1 1.1e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 EGG04093.1 - 0.0013 18.4 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGG04093.1 - 0.0044 16.4 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGG04093.1 - 0.0091 15.8 0.0 0.0091 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 EGG04093.1 - 0.0095 15.4 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase VirJ PF06057.6 EGG04093.1 - 0.019 14.7 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Thioesterase PF00975.15 EGG04093.1 - 0.022 14.9 0.0 0.03 14.5 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain DUF3089 PF11288.3 EGG04093.1 - 0.039 13.0 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) UPF0565 PF10561.4 EGG04093.1 - 0.08 11.8 0.0 0.097 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Peptidase_S10 PF00450.17 EGG04094.1 - 1.7e-90 304.1 3.6 2.2e-90 303.8 2.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase 3HCDH_N PF02737.13 EGG04095.1 - 6.2e-08 32.4 0.2 9e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF848 PF05852.6 EGG04095.1 - 0.26 11.1 2.6 0.49 10.2 1.6 1.7 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) zf-RVT PF13966.1 EGG04096.1 - 0.00087 19.5 0.9 0.0023 18.2 0.6 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Peptidase_S10 PF00450.17 EGG04097.1 - 7.3e-91 305.3 0.2 8.9e-91 305.1 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_5 PF12695.2 EGG04097.1 - 0.14 11.9 0.0 0.6 9.8 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family RNase_P_p30 PF01876.11 EGG04098.1 - 8.3e-27 93.2 0.0 1.3e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit p30 FAM110_C PF14160.1 EGG04098.1 - 0.088 13.7 0.8 0.38 11.7 0.1 2.1 2 0 0 2 2 2 0 Centrosome-associated C terminus COX14 PF14880.1 EGG04099.1 - 0.32 10.6 1.7 0.77 9.4 1.2 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Death_2 PF14786.1 EGG04103.1 - 0.034 13.8 0.1 0.058 13.1 0.1 1.4 1 0 0 1 1 1 0 Tube Death domain Cu_amine_oxid PF01179.15 EGG04103.1 - 0.13 10.9 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain Opi1 PF08618.5 EGG04103.1 - 1.6 7.5 15.1 0.37 9.6 1.7 2.1 1 1 1 2 2 2 0 Transcription factor Opi1 Podoplanin PF05808.6 EGG04103.1 - 4.1 6.9 5.7 6.7 6.2 1.3 2.4 2 1 0 2 2 2 0 Podoplanin DUF2867 PF11066.3 EGG04104.1 - 0.009 15.7 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2867) BUD22 PF09073.5 EGG04104.1 - 3.1 6.7 16.4 9.7 5.1 11.4 1.9 1 0 0 1 1 1 0 BUD22 Ribosomal_L29 PF00831.18 EGG04107.1 - 4.5e-18 64.6 2.3 4.5e-18 64.6 1.6 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EGG04107.1 - 0.0044 17.2 4.1 0.0065 16.7 2.8 1.5 1 1 0 1 1 1 1 Ribosomal protein S9/S16 ApoC-I PF04691.7 EGG04107.1 - 0.039 13.6 0.6 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Aconitase_2_N PF06434.8 EGG04107.1 - 0.072 12.4 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus Endonuc_Holl PF10107.4 EGG04107.1 - 0.13 11.9 1.8 0.14 11.8 0.1 1.8 1 1 1 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DUF607 PF04678.8 EGG04107.1 - 2.4 8.0 4.6 5.9 6.7 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF607 GATase_5 PF13507.1 EGG04108.1 - 9.2e-86 286.9 0.0 1.6e-85 286.1 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EGG04108.1 - 4.3e-42 143.7 0.0 8.2e-22 77.8 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EGG04108.1 - 9.4e-23 80.2 0.0 2.1e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain NST1 PF13945.1 EGG04114.1 - 0.18 11.8 3.6 0.24 11.4 2.5 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator zf-C2H2_4 PF13894.1 EGG04115.1 - 2.1e-10 40.1 50.4 0.043 14.1 1.6 7.1 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.21 EGG04115.1 - 9.3e-09 35.1 53.2 0.026 14.8 0.5 7.2 7 0 0 7 7 7 6 Zinc finger, C2H2 type Ogr_Delta PF04606.7 EGG04115.1 - 3.1e-05 23.5 31.3 0.00014 21.4 1.2 5.4 2 1 4 6 6 6 3 Ogr/Delta-like zinc finger zf-Di19 PF05605.7 EGG04115.1 - 0.016 15.2 5.7 0.016 15.2 3.9 3.8 3 2 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-HC5HC2H PF13771.1 EGG04115.1 - 0.027 14.6 28.9 1.8 8.7 0.6 6.2 1 1 5 6 6 6 0 PHD-like zinc-binding domain zf-tcix PF14952.1 EGG04115.1 - 0.11 11.8 20.8 3.4 7.0 0.3 5.6 7 0 0 7 7 7 0 Putative treble-clef, zinc-finger, Zn-binding DUF3505 PF12013.3 EGG04115.1 - 0.13 12.5 31.2 1.4 9.1 0.1 5.7 5 2 1 6 6 6 0 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 EGG04115.1 - 3.8 7.9 40.3 0.27 11.5 1.4 7.1 7 0 0 7 7 7 0 C2H2-type zinc-finger domain vMSA PF00695.14 EGG04118.1 - 0.018 14.2 1.0 0.29 10.2 0.5 2.0 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus Plasmodium_HRP PF05403.6 EGG04121.1 - 0.00082 19.0 1.4 0.00087 18.9 1.0 1.1 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) YonK PF09642.5 EGG04121.1 - 0.069 12.8 5.1 2.6 7.8 0.3 3.0 1 1 2 3 3 3 0 YonK protein DUF4266 PF14086.1 EGG04121.1 - 0.18 12.3 5.0 13 6.3 0.3 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4266) Nop14 PF04147.7 EGG04122.1 - 1.4 6.7 16.6 1.9 6.2 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_85 PF03644.8 EGG04123.1 - 1.3e-59 201.8 1.2 2.4e-59 201.0 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Acetyltransf_2 PF00797.12 EGG04125.1 - 1e-31 110.3 0.0 3.4e-28 98.8 0.0 2.3 2 1 0 2 2 2 2 N-acetyltransferase DUF3314 PF11771.3 EGG04125.1 - 0.094 12.4 0.0 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3314) zf-TFIIIC PF12660.2 EGG04126.1 - 3e-13 49.5 4.2 2.1e-12 46.8 2.3 2.5 2 1 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex FAM212 PF15342.1 EGG04127.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 FAM212 family UBN2_3 PF14244.1 EGG04129.1 - 0.095 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MacB_PCD PF12704.2 EGG04131.1 - 0.05 13.1 1.2 0.058 12.9 0.8 1.0 1 0 0 1 1 1 0 MacB-like periplasmic core domain Rho_GDI PF02115.12 EGG04132.1 - 5.6e-51 172.8 0.0 6.5e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Ribosomal_L12 PF00542.14 EGG04133.1 - 9.6e-23 79.9 9.9 2.4e-20 72.3 3.8 2.3 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain DUF2120 PF09893.4 EGG04133.1 - 0.085 12.7 3.0 0.59 10.0 2.1 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Tox-PL-2 PF15643.1 EGG04133.1 - 0.14 12.1 0.2 3 7.8 0.0 2.1 2 0 0 2 2 2 0 Papain fold toxin 2 DUF4208 PF13907.1 EGG04133.1 - 0.21 11.8 1.5 0.47 10.6 0.3 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4208) CDC37_C PF08564.5 EGG04133.1 - 0.26 11.1 6.6 2.9 7.8 0.3 3.0 1 1 1 3 3 3 0 Cdc37 C terminal domain AMMECR1 PF01871.12 EGG04134.1 - 3.4e-38 130.4 0.0 6.8e-38 129.4 0.0 1.4 1 1 0 1 1 1 1 AMMECR1 PQ-loop PF04193.9 EGG04136.1 - 1.1e-38 130.6 14.1 2.9e-19 68.3 0.6 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF3278 PF11683.3 EGG04136.1 - 0.0028 17.6 3.2 1.2 9.1 0.2 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3278) PAP2_C PF14360.1 EGG04136.1 - 0.081 13.2 0.2 0.081 13.2 0.2 2.9 3 1 0 3 3 3 0 PAP2 superfamily C-terminal DUF2975 PF11188.3 EGG04136.1 - 0.35 10.5 0.1 0.35 10.5 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) Zip PF02535.17 EGG04136.1 - 0.87 8.5 5.7 2.2 7.1 3.9 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter GPI-anchored PF10342.4 EGG04137.1 - 2.5e-11 43.9 0.8 4.6e-11 43.0 0.6 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 EGG04138.1 - 2.6e-07 31.0 5.8 2.6e-07 31.0 4.0 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1410 PF07198.6 EGG04138.1 - 0.016 15.5 1.5 0.04 14.2 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1410) RRM_1 PF00076.17 EGG04139.1 - 1.9e-38 129.9 2.4 2e-19 68.9 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG04139.1 - 6.2e-31 106.1 0.2 3.6e-15 55.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG04139.1 - 2.1e-15 56.3 0.1 1.7e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGG04139.1 - 0.0046 16.7 1.7 0.088 12.6 0.1 2.4 2 0 0 2 2 2 1 RNA binding motif DbpA PF03880.10 EGG04139.1 - 0.014 15.0 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain OB_RNB PF08206.6 EGG04139.1 - 0.024 14.1 0.3 7.9 6.0 0.0 3.1 2 0 0 2 2 2 0 Ribonuclease B OB domain Calcipressin PF04847.7 EGG04139.1 - 0.027 14.0 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Calcipressin Tim54 PF11711.3 EGG04140.1 - 0.0054 15.3 1.0 0.0064 15.1 0.7 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 TerB-C PF15615.1 EGG04140.1 - 0.085 13.1 3.7 0.18 12.0 2.5 1.6 1 1 0 1 1 1 0 TerB-C domain HWE_HK PF07536.9 EGG04140.1 - 0.13 12.7 1.5 0.22 11.9 1.1 1.5 1 0 0 1 1 1 0 HWE histidine kinase DUF4164 PF13747.1 EGG04140.1 - 0.14 12.2 5.8 0.23 11.6 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) MerR-DNA-bind PF09278.6 EGG04140.1 - 1.2 9.6 5.7 3.9 7.9 3.9 1.9 1 1 0 1 1 1 0 MerR, DNA binding DivIC PF04977.10 EGG04140.1 - 2.7 7.5 7.0 0.33 10.4 2.0 1.7 2 0 0 2 2 2 0 Septum formation initiator TIP49 PF06068.8 EGG04141.1 - 0.17 10.6 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus LRR_4 PF12799.2 EGG04142.1 - 0.01 15.4 5.3 1.3 8.7 0.2 3.7 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) TAFH PF07531.9 EGG04142.1 - 0.058 13.0 1.1 0.15 11.7 0.7 1.7 1 0 0 1 1 1 0 NHR1 homology to TAF Peptidase_M49 PF03571.10 EGG04143.1 - 9.4e-190 631.3 0.0 1.1e-189 631.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 zf-C2H2_jaz PF12171.3 EGG04144.1 - 5.2e-09 35.9 2.3 0.0007 19.6 0.8 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EGG04144.1 - 1.9e-07 30.9 7.6 0.0004 20.5 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 EGG04144.1 - 5.9e-06 26.2 3.2 0.0092 16.1 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EGG04144.1 - 1.7e-05 24.8 7.1 0.032 14.5 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGG04144.1 - 1.7e-05 24.5 7.5 0.0041 16.9 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EGG04144.1 - 5.9e-05 22.6 5.8 0.0039 16.8 0.0 3.2 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 EGG04144.1 - 0.00016 21.8 0.6 0.015 15.5 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_2 PF12756.2 EGG04144.1 - 0.00062 19.8 3.8 0.066 13.3 1.2 2.2 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) C1_2 PF03107.11 EGG04144.1 - 0.0022 18.0 4.0 3 8.0 0.1 3.3 3 0 0 3 3 3 1 C1 domain zf-FCS PF06467.9 EGG04144.1 - 0.012 15.1 2.4 1.6 8.3 0.3 2.4 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF3449 PF11931.3 EGG04144.1 - 0.029 13.8 0.4 3.6 7.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Elf1 PF05129.8 EGG04144.1 - 0.05 13.2 3.0 0.41 10.3 0.4 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-RING_2 PF13639.1 EGG04144.1 - 0.054 13.3 2.1 5.1 7.0 0.3 2.4 2 0 0 2 2 2 0 Ring finger domain zf-DBF PF07535.7 EGG04144.1 - 0.082 12.5 5.9 0.59 9.8 0.8 2.4 1 1 1 2 2 2 0 DBF zinc finger Evr1_Alr PF04777.8 EGG04144.1 - 0.15 11.9 3.9 2.6 7.9 1.6 2.2 1 1 1 2 2 2 0 Erv1 / Alr family Prok-RING_1 PF14446.1 EGG04144.1 - 0.19 11.4 2.8 10 5.9 0.2 2.6 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 zf-Di19 PF05605.7 EGG04144.1 - 0.21 11.7 3.0 0.58 10.3 2.1 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 EGG04144.1 - 0.31 11.0 5.6 10 6.1 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain FYVE PF01363.16 EGG04144.1 - 0.35 10.8 8.3 0.57 10.1 2.4 2.3 1 1 1 2 2 2 0 FYVE zinc finger XPA_N PF01286.13 EGG04144.1 - 0.44 10.2 4.2 7.3 6.3 0.3 2.4 2 0 0 2 2 2 0 XPA protein N-terminal Sgf11 PF08209.6 EGG04144.1 - 0.89 8.9 4.2 15 4.9 0.1 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) HNH PF01844.18 EGG04144.1 - 2.9 7.8 5.6 7.7 6.4 0.1 2.9 3 0 0 3 3 3 0 HNH endonuclease zf-AN1 PF01428.11 EGG04144.1 - 6.8 6.6 9.0 41 4.1 3.5 2.7 2 1 0 2 2 2 0 AN1-like Zinc finger FMN_dh PF01070.13 EGG04145.1 - 2e-101 339.4 0.0 1.2e-100 336.8 0.0 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EGG04145.1 - 2.8e-22 78.2 0.0 7.8e-22 76.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 EGG04145.1 - 0.00028 19.8 0.3 0.0014 17.6 0.1 2.1 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EGG04145.1 - 0.00067 18.6 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EGG04145.1 - 0.069 12.4 0.0 0.51 9.5 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein IF4E PF01652.13 EGG04146.1 - 4.9e-19 68.4 0.1 8.5e-19 67.6 0.0 1.4 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E DUF155 PF02582.9 EGG04147.1 - 0.019 14.8 0.1 0.098 12.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 CRAL_TRIO PF00650.15 EGG04149.1 - 3.4e-32 111.1 0.1 3.8e-31 107.7 0.2 2.3 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGG04149.1 - 8.7e-07 28.9 0.0 3.2e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGG04149.1 - 8.5e-06 25.7 0.1 1.6e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain tRNA-synt_1g PF09334.6 EGG04150.1 - 1.5e-98 330.0 0.2 4.4e-98 328.4 0.1 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGG04150.1 - 1.2e-11 43.3 1.7 4e-09 35.0 0.2 2.7 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGG04150.1 - 3.4e-05 23.6 0.0 6.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGG04150.1 - 5.9e-05 22.3 0.0 0.034 13.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain PSII_Pbs27 PF13326.1 EGG04155.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Photosystem II Pbs27 Acyltransferase PF01553.16 EGG04156.1 - 9.6e-29 99.4 0.0 1.3e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase ECF-ribofla_trS PF07155.7 EGG04156.1 - 0.012 15.3 0.3 0.017 14.8 0.2 1.2 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component 7TMR-DISM_7TM PF07695.6 EGG04156.1 - 0.039 13.6 1.3 0.058 13.0 0.9 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF4187 PF13821.1 EGG04158.1 - 2.6e-18 65.3 3.4 2.6e-18 65.3 2.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EGG04158.1 - 3.8e-08 32.9 0.3 5.2e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 G-patch domain G-patch_2 PF12656.2 EGG04158.1 - 0.16 11.8 4.5 0.19 11.6 0.4 3.0 2 1 0 2 2 2 0 DExH-box splicing factor binding site SUR7 PF06687.7 EGG04159.1 - 0.022 14.3 1.0 0.031 13.8 0.7 1.3 1 0 0 1 1 1 0 SUR7/PalI family SNF2_N PF00176.18 EGG04160.1 - 1.4e-60 204.6 0.1 2.1e-60 204.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGG04160.1 - 8.3e-13 48.0 0.0 1.9e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EGG04160.1 - 1.9e-07 30.8 7.3 6.9e-07 29.0 5.1 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGG04160.1 - 3.7e-06 26.5 6.5 1.1e-05 25.0 4.5 1.9 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 EGG04160.1 - 5.1e-06 26.0 0.0 2.2e-05 23.9 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 EGG04160.1 - 5.1e-06 26.0 9.0 5.1e-06 26.0 6.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG04160.1 - 1.8e-05 24.6 7.5 1.8e-05 24.6 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGG04160.1 - 2.7e-05 23.9 4.0 0.00013 21.7 2.8 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EGG04160.1 - 5e-05 22.8 6.5 0.00011 21.8 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGG04160.1 - 0.0042 16.7 3.9 0.0042 16.7 2.7 2.4 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EGG04160.1 - 0.0043 16.6 5.9 0.015 14.8 4.1 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF1253 PF06862.7 EGG04160.1 - 0.025 12.9 0.0 0.041 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) FYVE PF01363.16 EGG04160.1 - 0.11 12.3 5.1 0.53 10.2 3.5 2.2 1 1 1 2 2 2 0 FYVE zinc finger OrfB_Zn_ribbon PF07282.6 EGG04160.1 - 0.31 10.7 3.2 1.4 8.6 0.3 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-MIZ PF02891.15 EGG04160.1 - 6.1 6.4 8.1 24 4.5 5.6 2.1 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DUF1272 PF06906.6 EGG04160.1 - 7.3 6.5 7.8 3.9 7.3 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) TRAUB PF08164.7 EGG04162.1 - 1.2e-20 73.3 0.0 5.4e-20 71.2 0.0 2.2 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EGG04162.1 - 3.1e-20 72.6 3.3 8e-20 71.3 0.0 2.4 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor SART-1 PF03343.8 EGG04163.1 - 1.7e-113 380.1 80.3 1.7e-113 380.1 55.7 1.9 2 0 0 2 2 2 2 SART-1 family F-box PF00646.28 EGG04164.1 - 0.0059 16.2 1.0 0.51 10.0 0.2 3.5 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EGG04164.1 - 0.033 13.9 1.2 0.22 11.2 0.2 2.8 2 1 0 2 2 2 0 F-box-like F-box-like_2 PF13013.1 EGG04164.1 - 0.44 10.3 5.6 0.36 10.5 0.1 3.0 3 1 0 3 3 3 0 F-box-like domain IncA PF04156.9 EGG04165.1 - 7.1 6.1 6.9 13 5.2 4.8 1.4 1 0 0 1 1 1 0 IncA protein LRR_4 PF12799.2 EGG04166.1 - 3.5 7.3 13.5 4.5 7.0 0.2 4.7 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) TAFII28 PF04719.9 EGG04170.1 - 1.5e-26 91.9 0.0 2.6e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region RNA_pol_3_Rpc31 PF11705.3 EGG04170.1 - 2.3e-05 24.4 5.1 3.3e-05 23.9 3.5 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Prothymosin PF03247.9 EGG04170.1 - 0.0035 17.4 13.4 0.0051 16.9 9.3 1.2 1 0 0 1 1 1 1 Prothymosin/parathymosin family FYDLN_acid PF09538.5 EGG04170.1 - 0.015 15.9 7.9 0.022 15.3 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TT_ORF2 PF02957.10 EGG04170.1 - 0.029 15.0 5.0 0.049 14.3 3.5 1.4 1 0 0 1 1 1 0 TT viral ORF2 Tom22 PF04281.8 EGG04170.1 - 0.23 10.9 4.7 0.34 10.4 3.3 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Suf PF05843.9 EGG04170.1 - 0.48 10.1 5.8 0.59 9.8 4.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PBP_sp32 PF07222.7 EGG04170.1 - 0.53 9.4 5.0 0.77 8.8 3.5 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 ATAD4 PF15321.1 EGG04170.1 - 0.7 10.9 6.9 1.5 9.8 4.8 1.6 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 BTV_NS2 PF04514.7 EGG04170.1 - 0.98 8.2 8.3 1.3 7.8 5.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1764 PF08576.5 EGG04170.1 - 1.4 9.7 9.3 30 5.4 7.3 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) PPP4R2 PF09184.6 EGG04170.1 - 3.7 7.0 14.0 5.5 6.4 9.7 1.2 1 0 0 1 1 1 0 PPP4R2 Zn_clus PF00172.13 EGG04171.1 - 7.6e-07 28.9 6.8 1.6e-06 27.9 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.6 EGG04171.1 - 1.1 8.5 12.0 0.037 13.3 2.3 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator BNIP3 PF06553.7 EGG04172.1 - 0.25 10.6 10.5 0.43 9.9 4.0 2.3 2 0 0 2 2 2 0 BNIP3 DUF2791 PF10923.3 EGG04175.1 - 0.062 11.8 0.0 0.091 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Thiolase_N PF00108.18 EGG04176.1 - 7e-93 310.4 1.3 9.4e-93 309.9 0.9 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGG04176.1 - 1.2e-41 140.9 2.8 2.5e-41 139.9 0.8 2.3 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGG04176.1 - 0.00031 20.3 0.1 0.00071 19.1 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EGG04177.1 - 7.5e-12 45.4 0.0 1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG04177.1 - 8.4e-06 25.5 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 KR domain HHV6-IE PF03753.8 EGG04177.1 - 0.067 10.6 1.9 0.075 10.5 0.4 1.6 2 0 0 2 2 2 0 Human herpesvirus 6 immediate early protein Suppressor_P21 PF11479.3 EGG04177.1 - 0.15 11.7 0.8 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 RNA silencing suppressor P21 DUF2890 PF11081.3 EGG04179.1 - 0.0015 18.6 0.6 0.0022 18.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) GCM PF03615.10 EGG04179.1 - 0.084 12.4 2.9 0.33 10.5 2.0 1.9 1 1 0 1 1 1 0 GCM motif protein SDA1 PF05285.7 EGG04179.1 - 6.7 5.8 12.0 9.5 5.3 8.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EGG04179.1 - 7.9 4.2 13.9 2.9 5.6 7.8 1.5 2 0 0 2 2 2 0 Nop14-like family Pribosyltran PF00156.22 EGG04180.1 - 1.1e-15 57.5 0.1 1.4e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGG04180.1 - 0.0026 16.9 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 EGG04180.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 PRTase ComF-like Complex1_LYR PF05347.10 EGG04181.1 - 2.2e-07 30.5 1.8 3.6e-07 29.8 0.5 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGG04181.1 - 7.3e-06 26.1 1.1 9e-06 25.8 0.2 1.6 2 0 0 2 2 2 1 Complex1_LYR-like Histone PF00125.19 EGG04183.1 - 3e-14 52.9 0.1 3.5e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGG04183.1 - 2.9e-05 24.1 0.0 3.7e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EGG04183.1 - 9.1e-05 22.3 0.1 0.00012 22.0 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EGG04183.1 - 0.0011 19.0 0.1 0.002 18.1 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGG04183.1 - 0.045 12.9 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Auto_anti-p27 PF06677.7 EGG04184.1 - 1.7e-14 53.3 3.4 2.6e-09 36.7 0.4 2.8 3 0 0 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GTP_EFTU PF00009.22 EGG04185.1 - 6.8e-47 159.3 0.0 1.4e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGG04185.1 - 8e-25 86.9 0.3 3e-24 85.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGG04185.1 - 1.8e-10 40.7 0.3 6.3e-10 39.0 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGG04185.1 - 8e-05 22.5 0.0 0.00027 20.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGG04185.1 - 0.017 13.8 0.9 0.031 12.9 0.6 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Lar_restr_allev PF14354.1 EGG04186.1 - 0.039 14.2 0.1 0.061 13.6 0.1 1.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF3133 PF11331.3 EGG04186.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3133) SPC12 PF06645.8 EGG04187.1 - 4.8e-29 99.9 0.3 5.7e-29 99.7 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.9 EGG04187.1 - 0.009 16.3 0.1 0.011 16.1 0.1 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein Glyco_hydro_47 PF01532.15 EGG04189.1 - 9.9e-129 429.9 0.1 1.2e-128 429.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CHCH PF06747.8 EGG04190.1 - 1.6e-06 27.8 5.8 2e-06 27.5 4.0 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EGG04190.1 - 0.018 15.0 1.6 0.028 14.4 1.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EGG04190.1 - 0.033 13.9 1.1 0.046 13.5 0.8 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 EGG04190.1 - 0.058 13.3 0.1 0.068 13.1 0.0 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Fork_head PF00250.13 EGG04195.1 - 1.6e-22 79.3 0.0 1.8e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Fork head domain SCIMP PF15050.1 EGG04197.1 - 0.029 14.2 0.7 0.076 12.9 0.5 1.7 1 0 0 1 1 1 0 SCIMP protein PA28_beta PF02252.13 EGG04198.1 - 8.4e-26 90.2 0.0 1.4e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit Alpha_kinase PF02816.13 EGG04200.1 - 1.1e-11 44.7 0.0 1.5e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family DUF998 PF06197.8 EGG04201.1 - 0.006 15.9 1.7 0.0077 15.5 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Peroxin-22 PF12827.2 EGG04203.1 - 0.19 11.4 2.3 0.63 9.7 0.2 2.6 3 0 0 3 3 3 0 Peroxisomal biogenesis protein family MIP PF00230.15 EGG04204.1 - 2.5e-20 72.9 2.9 3.7e-19 69.1 2.0 2.0 1 1 0 1 1 1 1 Major intrinsic protein DUF3533 PF12051.3 EGG04204.1 - 0.81 8.3 3.7 1.2 7.7 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF805 PF05656.9 EGG04204.1 - 1.2 8.9 4.9 9.6 6.0 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF805) Aldedh PF00171.17 EGG04206.1 - 2.8e-72 243.5 0.0 3.5e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNA_pol_Rpb5_C PF01191.14 EGG04206.1 - 0.054 13.0 1.9 3.3 7.3 0.0 2.8 3 0 0 3 3 3 0 RNA polymerase Rpb5, C-terminal domain Myb_DNA-bind_6 PF13921.1 EGG04208.1 - 6e-29 99.9 11.1 3.1e-11 43.1 1.6 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGG04208.1 - 4.4e-27 93.8 8.4 9.3e-11 41.6 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EGG04208.1 - 0.0023 18.1 7.6 0.94 9.7 0.4 3.6 3 0 0 3 3 3 3 Alcohol dehydrogenase transcription factor Myb/SANT-like TrkH PF02386.11 EGG04213.1 - 2.6e-95 318.9 15.2 5.4e-90 301.5 4.4 2.2 2 0 0 2 2 2 2 Cation transport protein E1-E2_ATPase PF00122.15 EGG04214.1 - 1.4e-50 171.4 2.2 1.4e-50 171.4 1.5 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGG04214.1 - 5.4e-36 123.8 4.6 5.4e-36 123.8 3.2 3.2 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGG04214.1 - 2.5e-25 90.1 0.0 1.8e-24 87.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGG04214.1 - 2.6e-16 59.3 0.0 5.4e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGG04214.1 - 4.7e-10 39.9 0.0 1.1e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGG04214.1 - 2.6e-08 33.2 0.2 8e-08 31.6 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGG04214.1 - 2.3e-05 24.0 0.1 4.5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGG04215.1 - 1.1e-49 168.5 1.9 2.4e-49 167.4 0.9 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGG04215.1 - 3e-35 121.4 3.9 3e-35 121.4 2.7 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGG04215.1 - 3.7e-23 83.0 0.0 5.3e-22 79.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGG04215.1 - 5.3e-14 51.9 0.0 9.8e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGG04215.1 - 7.1e-08 31.8 0.0 2.2e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGG04215.1 - 4.1e-07 30.3 0.0 1.8e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGG04215.1 - 3e-05 23.7 0.3 5e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PaO PF08417.7 EGG04216.1 - 0.051 13.4 0.1 0.089 12.7 0.1 1.4 1 0 0 1 1 1 0 Pheophorbide a oxygenase Smg4_UPF3 PF03467.10 EGG04220.1 - 3.9e-28 98.6 0.2 6.8e-28 97.8 0.2 1.4 1 0 0 1 1 1 1 Smg-4/UPF3 family COX7a PF02238.10 EGG04221.1 - 0.00011 21.7 0.1 0.00014 21.4 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIa PsbL PF02419.12 EGG04221.1 - 0.07 12.5 0.3 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 PsbL protein Corona_nucleoca PF00937.13 EGG04222.1 - 0.2 10.5 5.9 0.26 10.1 4.1 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Sec7 PF01369.15 EGG04223.1 - 1.7e-21 76.7 0.1 1.8e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Sec7 domain Acyltransferase PF01553.16 EGG04225.1 - 1.8e-15 56.5 0.0 2.5e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase SIR2 PF02146.12 EGG04226.1 - 3.8e-30 104.9 0.0 1.9e-18 66.8 0.0 2.6 3 0 0 3 3 3 2 Sir2 family FtsH_ext PF06480.10 EGG04226.1 - 1.8 8.8 7.1 0.22 11.6 0.3 2.8 2 2 0 2 2 2 0 FtsH Extracellular NAD_binding_8 PF13450.1 EGG04230.1 - 4.8e-12 45.7 0.0 9.4e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGG04230.1 - 0.00023 20.1 0.1 0.00032 19.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGG04230.1 - 0.0012 18.9 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGG04230.1 - 0.0035 16.4 0.0 0.0041 16.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EGG04230.1 - 0.0082 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGG04230.1 - 0.034 14.0 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGG04230.1 - 0.074 11.5 0.1 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EGG04230.1 - 0.12 12.8 0.2 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ETRAMP PF09716.5 EGG04231.1 - 0.0077 16.1 0.0 0.16 11.9 0.0 2.7 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) CHASE3 PF05227.8 EGG04231.1 - 0.081 12.5 0.3 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 CHASE3 domain Gtr1_RagA PF04670.7 EGG04232.1 - 2.6e-53 180.5 0.4 3e-53 180.3 0.2 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EGG04232.1 - 1.7e-06 27.4 0.0 2.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EGG04232.1 - 0.019 15.4 0.0 0.062 13.7 0.0 1.9 1 1 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 EGG04232.1 - 0.026 14.4 0.0 0.048 13.6 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase HMGL-like PF00682.14 EGG04233.1 - 1.4e-13 51.0 0.0 2.4e-07 30.6 0.0 2.2 1 1 1 2 2 2 2 HMGL-like MAT1 PF06391.8 EGG04235.1 - 0.042 13.4 1.4 0.066 12.7 1.0 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 ASD2 PF08687.6 EGG04235.1 - 1.1 8.5 5.7 3.9 6.7 3.8 1.8 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 BCNT PF07572.7 EGG04235.1 - 1.8 8.5 6.3 1.1 9.1 1.1 2.5 1 1 2 3 3 3 0 Bucentaur or craniofacial development RHD3 PF05879.7 EGG04237.1 - 1.8e-234 780.0 9.5 3.1e-234 779.2 6.6 1.3 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EGG04237.1 - 4.3e-07 29.2 0.1 4.3e-07 29.2 0.1 1.9 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EGG04237.1 - 2.3e-05 24.3 0.1 9.1e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGG04237.1 - 2.4e-05 24.2 0.4 8.1e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 EGG04237.1 - 5.7e-05 23.5 0.0 0.00023 21.6 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EGG04237.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2660 PF10859.3 EGG04237.1 - 0.043 14.0 0.6 7.5 6.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2660) Arch_ATPase PF01637.13 EGG04237.1 - 0.062 12.9 1.8 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase Melibiase PF02065.13 EGG04239.1 - 0.0009 18.0 0.1 0.0015 17.2 0.1 1.3 1 0 0 1 1 1 1 Melibiase Cellulase PF00150.13 EGG04240.1 - 1.4e-17 63.8 0.0 1.5e-10 40.7 0.0 3.2 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.19 EGG04240.1 - 0.16 11.2 0.0 0.46 9.7 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Baculo_PEP_C PF04513.7 EGG04241.1 - 0.055 13.2 3.0 0.27 11.0 0.1 3.4 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Umbravirus_LDM PF04817.7 EGG04242.1 - 0.058 12.5 6.5 0.073 12.1 4.5 1.1 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family FRG2 PF15315.1 EGG04242.1 - 0.093 12.7 7.7 0.1 12.5 5.3 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 DUF3689 PF12463.3 EGG04242.1 - 0.096 11.4 0.2 0.12 11.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) PAP1 PF08601.5 EGG04242.1 - 0.19 11.3 9.0 0.19 11.3 6.2 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Pex14_N PF04695.8 EGG04242.1 - 0.6 10.1 4.9 0.7 9.9 3.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NST1 PF13945.1 EGG04242.1 - 2.2 8.3 8.3 2.6 8.0 5.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator MFS_1 PF07690.11 EGG04244.1 - 6.8e-33 113.8 24.0 1.9e-32 112.3 15.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.7 EGG04244.1 - 0.017 15.0 0.7 0.07 13.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 ESSS PF10183.4 EGG04244.1 - 0.14 12.5 2.1 1.7 9.0 0.1 2.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4083 PF13314.1 EGG04246.1 - 0.024 14.4 4.0 0.78 9.6 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Pox_A14 PF05767.7 EGG04246.1 - 0.095 12.6 4.1 0.43 10.5 1.4 2.6 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Amastin PF07344.6 EGG04246.1 - 0.17 11.5 11.7 0.04 13.5 5.2 2.0 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF3188 PF11384.3 EGG04246.1 - 1.5 8.4 5.9 0.77 9.3 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) DUF4064 PF13273.1 EGG04246.1 - 2.6 8.1 13.4 0.75 9.9 4.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) Tetraspannin PF00335.15 EGG04246.1 - 2.8 7.1 14.4 0.52 9.5 5.1 2.7 1 1 1 2 2 2 0 Tetraspanin family DnaJ PF00226.26 EGG04247.1 - 1e-10 41.2 0.3 3.7e-10 39.4 0.0 2.1 3 0 0 3 3 3 1 DnaJ domain Apc3 PF12895.2 EGG04247.1 - 0.0064 16.6 7.6 0.018 15.1 0.0 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF309 PF03745.9 EGG04247.1 - 0.036 13.5 0.1 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF309) TPR_11 PF13414.1 EGG04247.1 - 0.06 12.9 1.1 1.1 9.0 0.0 2.9 3 1 1 4 4 4 0 TPR repeat TPR_19 PF14559.1 EGG04247.1 - 0.1 12.9 0.0 4.9 7.5 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat CK2S PF15011.1 EGG04248.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Casein Kinase 2 substrate Dscam_C PF12355.3 EGG04250.1 - 0.021 15.0 1.9 0.031 14.5 1.3 1.2 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Ndc1_Nup PF09531.5 EGG04250.1 - 2.8 6.2 5.9 3 6.1 4.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup JmjC PF02373.17 EGG04251.1 - 2.9e-13 50.0 0.1 1.1e-12 48.1 0.1 2.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase Peptidase_S8 PF00082.17 EGG04252.1 - 5.1e-41 140.6 0.4 9.8e-41 139.7 0.3 1.5 1 0 0 1 1 1 1 Subtilase family Methyltransf_28 PF02636.12 EGG04253.1 - 2.7e-35 122.0 0.0 3.6e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 EGG04253.1 - 0.051 14.0 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGG04253.1 - 0.19 11.3 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RNA_pol_Rpb4 PF03874.11 EGG04256.1 - 1e-18 67.4 1.2 1.9e-18 66.5 0.8 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb4 Pcc1 PF09341.5 EGG04256.1 - 0.038 14.0 0.3 0.083 12.9 0.2 1.5 1 1 0 1 1 1 0 Transcription factor Pcc1 HrpB2 PF09487.5 EGG04256.1 - 0.083 13.0 0.2 0.34 11.1 0.0 1.9 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB2) Acetyltransf_7 PF13508.1 EGG04257.1 - 2.2e-09 37.3 0.0 2e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGG04257.1 - 1.6e-08 34.4 0.0 3.4e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGG04257.1 - 7.6e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGG04257.1 - 0.00021 21.4 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EGG04257.1 - 0.00054 19.3 0.0 0.00072 18.9 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Acetyltransf_3 PF13302.1 EGG04257.1 - 0.0035 17.4 0.0 0.11 12.6 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGG04257.1 - 0.0045 16.8 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Amidohydro_1 PF01979.15 EGG04258.1 - 8.2e-05 22.4 0.0 8.7e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family CDC45 PF02724.9 EGG04262.1 - 0.12 10.3 7.9 0.15 10.1 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.5 EGG04262.1 - 5.7 5.2 6.7 6.3 5.0 4.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DBD_Tnp_Mut PF03108.10 EGG04263.1 - 0.0044 16.5 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 MuDR family transposase Glyco_hydro_2_N PF02837.13 EGG04264.1 - 3.6e-26 91.6 0.0 1.2e-25 90.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EGG04264.1 - 5.8e-10 39.6 0.0 1.6e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EGG04264.1 - 1.2e-05 24.3 0.0 3.7e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain DRIM PF07539.7 EGG04265.1 - 3.6e-35 120.4 0.0 2e-33 114.7 0.0 3.6 3 0 0 3 3 3 1 Down-regulated in metastasis HEAT PF02985.17 EGG04265.1 - 2.3e-05 24.0 1.0 32 4.9 0.0 7.9 8 0 0 8 8 8 1 HEAT repeat Arm PF00514.18 EGG04265.1 - 0.0039 16.9 6.6 0.0088 15.8 0.0 5.1 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Cornifin PF02389.10 EGG04266.1 - 3.1e-05 23.8 18.4 5.1e-05 23.1 12.8 1.4 1 0 0 1 1 1 1 Cornifin (SPRR) family TMF_DNA_bd PF12329.3 EGG04266.1 - 0.31 10.8 2.6 0.74 9.6 1.8 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Glyco_hydro_2_N PF02837.13 EGG04268.1 - 1.4e-27 96.3 0.0 2.9e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EGG04268.1 - 6.6e-12 45.8 0.1 1.6e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EGG04268.1 - 1.5e-06 27.3 0.0 3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain FMN_bind_2 PF04299.7 EGG04268.1 - 0.026 14.0 0.2 0.052 13.0 0.1 1.4 1 0 0 1 1 1 0 Putative FMN-binding domain SelR PF01641.13 EGG04269.1 - 1.5e-46 157.0 0.0 1.8e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 SelR domain DnaJ_CXXCXGXG PF00684.14 EGG04269.1 - 0.11 12.5 0.6 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 DnaJ central domain STAT_alpha PF01017.15 EGG04271.1 - 0.049 13.3 0.6 0.049 13.3 0.4 1.9 2 0 0 2 2 2 0 STAT protein, all-alpha domain CDK5_activator PF03261.10 EGG04271.1 - 0.47 9.7 6.3 0.83 8.9 4.4 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4140 PF13600.1 EGG04271.1 - 2.2 8.7 6.7 18 5.8 0.2 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF422 PF04240.7 EGG04274.1 - 0.018 14.4 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF422) DUF3522 PF12036.3 EGG04274.1 - 0.045 13.5 0.1 0.051 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) YoqO PF14037.1 EGG04274.1 - 0.08 13.0 0.1 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 YoqO-like protein 7TMR-DISM_7TM PF07695.6 EGG04274.1 - 0.1 12.2 0.3 0.13 11.9 0.2 1.0 1 0 0 1 1 1 0 7TM diverse intracellular signalling RNA_pol_Rpc4 PF05132.9 EGG04278.1 - 5.5e-20 71.6 0.7 2.6e-19 69.4 0.0 2.4 1 1 1 2 2 2 1 RNA polymerase III RPC4 TelA PF05816.6 EGG04279.1 - 0.0097 14.6 0.6 2.7 6.5 0.1 2.1 2 0 0 2 2 2 2 Toxic anion resistance protein (TelA) TelA PF05816.6 EGG04280.1 - 0.0081 14.9 1.0 2 7.0 0.1 2.1 2 0 0 2 2 2 2 Toxic anion resistance protein (TelA) FAD_binding_3 PF01494.14 EGG04281.1 - 2.8e-19 69.3 0.0 4.1e-18 65.5 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGG04281.1 - 4.9e-06 26.4 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGG04281.1 - 5.3e-05 23.5 0.0 0.00029 21.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGG04281.1 - 0.00072 18.5 0.1 0.0013 17.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 EGG04281.1 - 0.0024 16.7 0.0 1.2 7.8 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Trp_halogenase PF04820.9 EGG04281.1 - 0.015 13.9 0.0 0.29 9.7 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.19 EGG04281.1 - 0.03 13.1 0.0 1 8.0 0.0 2.1 1 1 1 2 2 2 0 FAD binding domain GIDA PF01134.17 EGG04281.1 - 0.06 12.2 0.0 0.092 11.5 0.0 1.3 1 1 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EGG04281.1 - 0.064 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EGG04281.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Flavin_Reduct PF01613.13 EGG04282.1 - 1.3e-22 80.2 0.0 1.7e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Ras PF00071.17 EGG04283.1 - 1.2e-10 40.9 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Ras family CHZ PF09649.5 EGG04283.1 - 0.87 8.8 6.9 0.39 9.9 0.4 2.8 3 0 0 3 3 3 0 Histone chaperone domain CHZ Pox_Ag35 PF03286.9 EGG04284.1 - 0.17 11.4 10.8 0.2 11.1 7.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.1 EGG04284.1 - 0.21 11.9 21.0 11 6.3 14.5 2.3 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Poxvirus_B22R PF04395.7 EGG04284.1 - 0.83 9.1 6.8 1.1 8.7 4.7 1.1 1 0 0 1 1 1 0 Poxvirus B22R protein DNA_pol_phi PF04931.8 EGG04284.1 - 1.2 6.8 12.4 1.5 6.5 8.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3245 PF11595.3 EGG04284.1 - 1.8 8.8 10.0 3.3 7.9 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Prothymosin PF03247.9 EGG04284.1 - 2.4 8.3 14.0 4.7 7.3 9.7 1.5 1 1 0 1 1 1 0 Prothymosin/parathymosin family FAM60A PF15396.1 EGG04284.1 - 3 7.5 6.2 3.6 7.2 4.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.12 EGG04284.1 - 5.7 5.6 6.8 6.8 5.4 4.7 1.0 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.5 EGG04287.1 - 0.3 11.0 10.2 0.36 10.8 7.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPP4R2 PF09184.6 EGG04287.1 - 4.5 6.7 18.3 5.3 6.4 12.7 1.0 1 0 0 1 1 1 0 PPP4R2 Gag_spuma PF03276.9 EGG04287.1 - 8 4.6 11.8 7.8 4.6 8.2 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Glyco_hydro_4C PF11975.3 EGG04288.1 - 0.051 13.3 2.0 0.16 11.6 1.4 1.8 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain API5 PF05918.6 EGG04288.1 - 0.43 9.0 4.0 0.7 8.3 2.8 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF1487 PF07368.6 EGG04292.1 - 0.13 11.4 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) DUF1217 PF06748.7 EGG04294.1 - 0.023 14.7 0.6 0.16 12.0 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1217) PT PF04886.7 EGG04296.1 - 3.3 7.1 10.0 3.3 7.0 2.8 2.7 2 0 0 2 2 2 0 PT repeat Plasmid_stabil PF05016.9 EGG04298.1 - 0.037 14.4 0.3 0.061 13.7 0.2 1.3 1 0 0 1 1 1 0 Plasmid stabilisation system protein MF_alpha PF04648.7 EGG04298.1 - 0.6 10.4 5.0 0.76 10.1 2.5 1.9 2 0 0 2 2 2 0 Yeast mating factor alpha hormone TPR_1 PF00515.23 EGG04299.1 - 0.036 13.6 0.0 0.083 12.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGG04299.1 - 0.06 13.3 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat CCDC-167 PF15188.1 EGG04300.1 - 0.016 15.1 1.4 0.016 15.1 1.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Desmo_N PF06771.6 EGG04300.1 - 0.09 12.7 0.1 0.28 11.1 0.1 1.8 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus F-box-like PF12937.2 EGG04304.1 - 0.0065 16.1 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGG04304.1 - 0.066 12.8 1.6 0.18 11.4 1.1 1.7 1 0 0 1 1 1 0 F-box domain Rac1 PF09632.5 EGG04305.1 - 0.06 12.4 0.3 0.085 11.9 0.2 1.3 1 0 0 1 1 1 0 Rac1-binding domain Cys_Met_Meta_PP PF01053.15 EGG04308.1 - 3.8e-123 410.6 0.0 5.2e-123 410.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 EGG04308.1 - 1.1e-18 67.0 1.4 8.9e-18 64.1 0.8 2.6 2 0 0 2 2 2 1 GHMP kinases N terminal domain Met_gamma_lyase PF06838.6 EGG04308.1 - 6.6e-05 21.3 0.1 0.00016 20.0 0.1 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 EGG04308.1 - 0.00026 20.0 0.0 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EGG04308.1 - 0.00073 18.6 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GalKase_gal_bdg PF10509.4 EGG04308.1 - 0.0026 17.0 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Beta_elim_lyase PF01212.16 EGG04308.1 - 0.0033 16.6 0.0 0.0072 15.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase GHMP_kinases_C PF08544.8 EGG04308.1 - 0.043 14.0 0.1 0.17 12.1 0.1 2.2 1 0 0 1 1 1 0 GHMP kinases C terminal Nop14 PF04147.7 EGG04310.1 - 0.032 12.1 18.1 0.044 11.7 12.5 1.1 1 0 0 1 1 1 0 Nop14-like family PglZ PF08665.7 EGG04310.1 - 0.071 12.7 0.0 0.071 12.7 0.0 1.9 2 0 0 2 2 2 0 PglZ domain DUF4636 PF15468.1 EGG04310.1 - 0.072 12.5 3.7 0.14 11.5 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF1752 PF08550.5 EGG04310.1 - 0.089 12.3 0.4 0.17 11.4 0.3 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) CDC45 PF02724.9 EGG04310.1 - 0.1 10.6 16.8 0.16 10.0 11.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EGG04310.1 - 0.12 11.6 16.6 0.21 10.8 11.5 1.3 1 0 0 1 1 1 0 SDA1 Merozoite_SPAM PF07133.6 EGG04310.1 - 0.36 10.6 25.8 0.81 9.5 17.9 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF1510 PF07423.6 EGG04310.1 - 1 8.7 19.7 1.8 7.8 13.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 EGG04310.1 - 1 9.1 6.9 1.7 8.3 4.8 1.3 1 0 0 1 1 1 0 DDHD domain Nop53 PF07767.6 EGG04310.1 - 1.3 7.9 17.9 2 7.3 12.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TRAP_alpha PF03896.11 EGG04310.1 - 2.3 7.1 11.8 4 6.3 8.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ycf1 PF05758.7 EGG04310.1 - 2.3 5.7 8.5 3.7 5.1 5.9 1.2 1 0 0 1 1 1 0 Ycf1 VID27 PF08553.5 EGG04310.1 - 2.4 6.2 13.9 3.9 5.5 9.6 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein HSP90 PF00183.13 EGG04310.1 - 2.5 6.4 16.6 4.7 5.4 11.5 1.4 1 0 0 1 1 1 0 Hsp90 protein Sigma70_ner PF04546.8 EGG04310.1 - 2.5 7.6 18.3 4.1 6.9 12.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.1 EGG04310.1 - 4.8 7.3 15.9 56 3.9 10.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Herpes_DNAp_acc PF04929.7 EGG04310.1 - 5 5.9 6.7 7.4 5.4 4.6 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Tim54 PF11711.3 EGG04310.1 - 5.9 5.3 9.9 9.3 4.7 6.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Daxx PF03344.10 EGG04310.1 - 9.2 4.6 24.8 13 4.1 17.2 1.1 1 0 0 1 1 1 0 Daxx Family RP-C_C PF11800.3 EGG04310.1 - 9.7 5.8 7.4 15 5.1 5.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Nucleopor_Nup85 PF07575.8 EGG04312.1 - 1.7e-73 247.7 5.1 6.3e-73 245.8 3.5 1.8 1 1 0 1 1 1 1 Nup85 Nucleoporin PPP4R2 PF09184.6 EGG04314.1 - 0.00036 20.1 14.3 0.00081 19.0 8.0 2.6 2 1 0 2 2 2 1 PPP4R2 MNE1 PF13762.1 EGG04315.1 - 0.022 14.8 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component PAN_1 PF00024.21 EGG04316.1 - 0.022 14.4 6.1 0.061 13.0 4.2 1.8 1 1 0 1 1 1 0 PAN domain MIS13 PF08202.6 EGG04317.1 - 0.0068 15.5 0.0 0.0075 15.3 0.0 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Isy1 PF06246.7 EGG04317.1 - 0.0079 15.6 0.4 0.012 15.0 0.3 1.2 1 0 0 1 1 1 1 Isy1-like splicing family KH_1 PF00013.24 EGG04318.1 - 4.3e-07 29.4 0.0 0.00011 21.8 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EGG04318.1 - 1.5e-05 24.5 0.5 0.003 17.1 0.1 2.6 2 0 0 2 2 2 2 KH domain Trp_repressor PF01371.14 EGG04318.1 - 0.1 12.5 0.1 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein DUF1510 PF07423.6 EGG04319.1 - 0.15 11.3 16.9 0.17 11.2 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 EGG04319.1 - 0.24 9.0 3.8 0.21 9.2 2.6 1.0 1 0 0 1 1 1 0 Ycf1 BUD22 PF09073.5 EGG04319.1 - 1.2 8.0 21.0 1.5 7.8 14.5 1.2 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.11 EGG04319.1 - 3.2 6.6 18.7 3.8 6.4 13.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pilt PF15453.1 EGG04319.1 - 4.7 6.7 9.0 5.6 6.5 6.2 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Spore_coat_CotO PF14153.1 EGG04319.1 - 5.8 6.3 15.8 7.6 5.9 11.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CobT PF06213.7 EGG04319.1 - 6.5 5.7 28.5 7.6 5.5 19.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid PF03115.9 EGG04319.1 - 8.1 4.5 8.6 8.1 4.5 6.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RNA_polI_A34 PF08208.6 EGG04319.1 - 8.4 6.0 11.6 11 5.6 8.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Nop14 PF04147.7 EGG04319.1 - 8.4 4.1 36.6 9.8 3.9 25.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EGG04319.1 - 9 5.4 30.3 9.9 5.3 21.0 1.1 1 0 0 1 1 1 0 SDA1 MIP PF00230.15 EGG04320.1 - 1.4e-46 158.7 2.8 1.9e-46 158.3 1.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein TauE PF01925.14 EGG04320.1 - 2.4 7.5 12.3 2.5 7.5 4.3 2.8 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE DUF1764 PF08576.5 EGG04324.1 - 7.3e-14 52.3 1.2 7.3e-14 52.3 0.8 2.3 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) DUF4175 PF13779.1 EGG04324.1 - 0.058 11.1 4.6 0.076 10.7 3.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SGT1 PF07093.6 EGG04324.1 - 0.29 9.4 12.1 0.32 9.3 8.4 1.0 1 0 0 1 1 1 0 SGT1 protein Bud13 PF09736.4 EGG04324.1 - 0.33 11.1 16.1 0.49 10.6 11.2 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex BTV_NS2 PF04514.7 EGG04324.1 - 0.36 9.6 11.6 0.43 9.4 8.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Vfa1 PF08432.5 EGG04324.1 - 0.49 10.3 18.5 0.61 10.0 12.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CKAP2_C PF15297.1 EGG04324.1 - 0.56 8.9 15.4 0.72 8.6 10.7 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Tom37_C PF11801.3 EGG04324.1 - 0.65 9.8 10.2 0.84 9.4 7.1 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF1510 PF07423.6 EGG04324.1 - 1.2 8.4 18.2 1.6 8.0 12.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Elongin_A PF06881.6 EGG04324.1 - 1.6 9.1 10.7 2.6 8.4 7.4 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A NARP1 PF12569.3 EGG04324.1 - 1.8 7.2 15.3 2.2 6.9 10.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.11 EGG04324.1 - 2.1 8.1 5.0 2.5 7.9 3.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FLO_LFY PF01698.11 EGG04324.1 - 4.8 5.9 10.7 6 5.5 7.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TFIIF_alpha PF05793.7 EGG04324.1 - 5.4 5.2 25.7 6.3 5.0 17.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GAGA_bind PF06217.7 EGG04324.1 - 5.5 6.8 12.3 6.5 6.6 8.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2201_N PF13203.1 EGG04324.1 - 6.3 5.8 7.1 7.8 5.5 4.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain NST1 PF13945.1 EGG04324.1 - 6.9 6.6 20.7 11 5.9 14.3 1.3 1 1 0 1 1 1 0 Salt tolerance down-regulator Hid1 PF12722.2 EGG04324.1 - 8.1 3.9 12.3 10 3.6 8.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2413 PF10310.4 EGG04324.1 - 8.5 5.0 17.5 10 4.7 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) zf-CCHC PF00098.18 EGG04326.1 - 0.0016 18.2 3.3 0.0016 18.2 2.3 1.7 2 0 0 2 2 2 1 Zinc knuckle Zn-ribbon_8 PF09723.5 EGG04326.1 - 1.2 9.1 6.3 2.6 8.0 0.2 3.0 3 0 0 3 3 3 0 Zinc ribbon domain F-box-like PF12937.2 EGG04327.1 - 0.00058 19.5 0.1 0.0014 18.3 0.0 1.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EGG04327.1 - 0.0044 16.6 0.2 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 F-box domain Endonuc-FokI_C PF09254.6 EGG04327.1 - 0.028 13.5 0.6 0.039 13.0 0.4 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal DUF244 PF03112.9 EGG04328.1 - 0.6 9.6 3.8 0.23 10.9 0.4 1.9 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF DUF3811 PF11656.3 EGG04330.1 - 1.6 8.8 8.8 4.9 7.2 6.0 1.8 1 1 0 1 1 1 0 YjbD family (DUF3811) DUF2387 PF09526.5 EGG04331.1 - 0.02 14.8 0.1 0.063 13.2 0.0 1.8 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) DUF559 PF04480.7 EGG04335.1 - 0.044 13.4 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF559) SKN1 PF03935.10 EGG04336.1 - 0.0031 15.7 0.0 0.0038 15.4 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) G-alpha PF00503.15 EGG04337.1 - 5.9e-05 21.9 1.8 6.7e-05 21.7 0.6 1.4 1 1 1 2 2 2 1 G-protein alpha subunit Peptidase_S9 PF00326.16 EGG04338.1 - 4e-52 176.5 0.0 6.7e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGG04338.1 - 5.1e-10 39.2 0.0 1.1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG04338.1 - 1.6e-05 24.9 0.1 9.7e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EGG04338.1 - 0.0072 14.8 0.0 0.24 9.8 0.0 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Asp PF00026.18 EGG04340.1 - 7.6e-23 81.2 0.0 2.4e-22 79.6 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG04340.1 - 4e-07 30.1 0.0 1.9e-05 24.6 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal SieB PF14163.1 EGG04341.1 - 0.22 11.1 2.4 9.2 5.8 0.4 2.6 2 0 0 2 2 2 0 Superinfection exclusion protein B ABC2_membrane PF01061.19 EGG04341.1 - 0.27 10.3 4.8 0.29 10.2 0.6 2.4 3 0 0 3 3 3 0 ABC-2 type transporter DNA_pol_B PF00136.16 EGG04342.1 - 1.5e-143 478.9 1.0 2.3e-143 478.3 0.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGG04342.1 - 9.9e-81 271.1 0.0 1.8e-80 270.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EGG04342.1 - 2.9e-22 78.4 5.2 2.9e-22 78.4 3.6 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 EGG04342.1 - 0.00012 21.6 0.1 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EGG04342.1 - 0.0044 16.8 0.4 0.02 14.7 0.3 2.1 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 EGG04342.1 - 0.0045 15.7 3.8 0.014 14.1 0.9 2.5 2 1 0 2 2 2 1 DNA polymerase type B, organellar and viral C1_1 PF00130.17 EGG04342.1 - 2.4 7.9 6.8 19 5.0 0.6 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Imm24 PF15570.1 EGG04344.1 - 0.0084 15.8 2.4 0.064 12.9 0.6 2.4 2 0 0 2 2 2 1 Immunity protein 24 DUF947 PF06102.7 EGG04344.1 - 0.011 15.5 1.5 0.017 14.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF947) DUF848 PF05852.6 EGG04345.1 - 0.0096 15.7 3.5 0.014 15.2 2.4 1.3 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) Uds1 PF15456.1 EGG04345.1 - 0.016 15.1 7.7 0.026 14.5 2.7 2.1 1 1 1 2 2 2 0 Up-regulated During Septation DUF1395 PF07160.7 EGG04345.1 - 0.037 13.5 0.9 0.044 13.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Med9 PF07544.8 EGG04345.1 - 0.041 13.6 2.2 0.79 9.4 1.5 2.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 FliJ PF02050.11 EGG04345.1 - 0.054 13.5 2.6 0.1 12.6 1.8 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein Baculo_PEP_C PF04513.7 EGG04345.1 - 0.074 12.8 1.9 0.13 12.1 1.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cast PF10174.4 EGG04345.1 - 0.081 10.9 6.6 0.096 10.7 4.6 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF2175 PF09943.4 EGG04345.1 - 0.11 12.5 2.4 0.13 12.2 1.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) IncA PF04156.9 EGG04345.1 - 0.13 11.8 10.6 0.16 11.5 7.4 1.1 1 0 0 1 1 1 0 IncA protein Tropomyosin_1 PF12718.2 EGG04345.1 - 0.32 10.8 8.8 0.072 12.9 4.1 1.4 2 0 0 2 2 2 0 Tropomyosin like TBPIP PF07106.8 EGG04345.1 - 0.47 9.9 6.8 0.45 10.0 3.2 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 EGG04345.1 - 0.5 10.2 3.4 37 4.3 2.4 2.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 EGG04345.1 - 0.57 10.0 9.3 0.75 9.6 5.5 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.1 EGG04345.1 - 0.63 9.9 6.9 1.5 8.7 4.7 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CCDC-167 PF15188.1 EGG04345.1 - 0.7 9.8 5.5 0.24 11.3 2.0 1.6 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 Prefoldin_2 PF01920.15 EGG04345.1 - 0.96 9.2 6.5 7.7 6.3 0.2 2.7 2 1 1 3 3 3 0 Prefoldin subunit COG5 PF10392.4 EGG04345.1 - 1.3 8.9 7.7 5.4 6.9 5.4 1.9 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Occludin_ELL PF07303.8 EGG04345.1 - 1.7 9.3 5.1 32 5.3 0.7 3.0 2 1 1 3 3 3 0 Occludin homology domain TMF_DNA_bd PF12329.3 EGG04345.1 - 2.1 8.2 7.2 5.3 6.9 0.1 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4218 PF13960.1 EGG04346.1 - 0.0018 17.7 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Plasmid_stabil PF05016.9 EGG04346.1 - 0.057 13.8 0.0 20 5.6 0.0 3.4 3 0 0 3 3 3 0 Plasmid stabilisation system protein Sad1_UNC PF07738.8 EGG04347.1 - 1.4e-27 96.1 0.0 2.6e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF2721 PF11026.3 EGG04347.1 - 0.1 12.1 0.3 0.98 9.0 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) BLOC1_2 PF10046.4 EGG04347.1 - 3.7 7.7 9.0 2.1 8.5 3.5 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BLOC1_2 PF10046.4 EGG04348.1 - 0.0011 19.0 16.1 0.08 13.0 1.9 4.0 2 1 2 4 4 4 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mit_KHE1 PF10173.4 EGG04348.1 - 0.06 13.2 0.4 0.11 12.2 0.3 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related TBPIP PF07106.8 EGG04348.1 - 0.081 12.4 21.6 3.1 7.3 0.0 3.8 2 2 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fzo_mitofusin PF04799.8 EGG04348.1 - 0.14 11.5 18.0 0.052 12.9 4.4 3.1 2 1 0 3 3 3 0 fzo-like conserved region DUF842 PF05811.8 EGG04348.1 - 0.14 11.5 10.4 0.026 13.9 3.5 2.4 2 2 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) FlaC_arch PF05377.6 EGG04348.1 - 0.16 11.8 10.4 1.3 8.9 0.2 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.3 EGG04348.1 - 0.19 11.5 5.7 4 7.2 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) Reo_sigmaC PF04582.7 EGG04348.1 - 0.21 10.7 12.2 0.74 8.9 3.3 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein IncA PF04156.9 EGG04348.1 - 0.35 10.4 27.7 0.84 9.1 4.7 3.4 1 1 1 2 2 2 0 IncA protein DUF1664 PF07889.7 EGG04348.1 - 0.7 9.7 17.2 1.5 8.6 0.3 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF310 PF03750.8 EGG04348.1 - 1.2 9.3 5.8 8.6 6.5 0.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF310) ORF6C PF10552.4 EGG04348.1 - 1.6 8.4 7.1 1.2 8.8 0.1 3.1 2 1 0 3 3 3 0 ORF6C domain Med11 PF10280.4 EGG04348.1 - 1.8 8.6 11.5 3.6 7.6 0.8 3.3 3 0 0 3 3 3 0 Mediator complex protein FliD_N PF02465.13 EGG04348.1 - 2.3 8.6 11.4 4.7 7.6 0.3 3.6 2 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Lipoprotein_20 PF13942.1 EGG04348.1 - 2.3 7.7 15.3 0.15 11.5 0.3 2.9 2 2 0 2 2 2 0 YfhG lipoprotein DUF972 PF06156.8 EGG04348.1 - 2.6 8.4 16.7 3.6 7.9 2.8 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF972) DASH_Dam1 PF08653.5 EGG04348.1 - 3.3 7.5 11.4 0.79 9.5 0.5 3.7 4 0 0 4 4 4 0 DASH complex subunit Dam1 OmpH PF03938.9 EGG04348.1 - 3.5 7.5 10.9 7.8 6.4 7.6 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF948 PF06103.6 EGG04348.1 - 3.9 7.4 6.7 3.2 7.6 0.2 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.17 EGG04348.1 - 5.8 6.9 13.3 0.69 9.9 1.0 2.6 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 EGG04349.1 - 0.56 8.5 2.5 0.92 7.8 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Snapin_Pallidin PF14712.1 EGG04349.1 - 3.4 8.0 8.4 1.6 9.0 0.2 3.3 3 0 0 3 3 3 0 Snapin/Pallidin AzlC PF03591.9 EGG04350.1 - 0.58 10.0 14.3 0.18 11.7 6.4 2.2 2 0 0 2 2 2 0 AzlC protein zf-DHHC PF01529.15 EGG04350.1 - 0.98 8.7 5.3 10 5.4 3.7 2.1 1 1 0 1 1 1 0 DHHC palmitoyltransferase Glyco_hydro_7 PF00840.15 EGG04352.1 - 2.4e-167 556.6 11.0 2.9e-167 556.4 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fer2_3 PF13085.1 EGG04354.1 - 3e-33 113.9 0.0 4.9e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EGG04354.1 - 6.5e-10 39.2 5.9 6.5e-10 39.2 4.1 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EGG04354.1 - 5.4e-09 35.9 4.9 5.4e-09 35.9 3.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGG04354.1 - 6.4e-05 23.1 5.7 0.023 14.9 0.3 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGG04354.1 - 0.00017 21.2 4.9 0.00017 21.2 3.4 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGG04354.1 - 0.00023 21.4 2.4 0.00023 21.4 1.7 2.6 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 EGG04354.1 - 0.00072 19.8 4.7 0.00072 19.8 3.2 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EGG04354.1 - 0.025 14.3 0.3 0.025 14.3 0.2 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DUF3688 PF12461.3 EGG04354.1 - 0.092 13.1 0.1 2.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3688) Fer4_15 PF13459.1 EGG04354.1 - 0.5 10.9 6.9 0.94 10.0 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain CFEM PF05730.6 EGG04356.1 - 4 7.3 8.0 7.6 6.4 5.2 1.8 1 1 1 2 2 2 0 CFEM domain Toxin_17 PF08086.6 EGG04357.1 - 0.056 13.5 4.9 0.056 13.5 3.4 1.8 2 0 0 2 2 2 0 Ergtoxin family PCI PF01399.22 EGG04358.1 - 1.4e-12 47.8 1.0 3.2e-12 46.7 0.7 1.6 1 0 0 1 1 1 1 PCI domain Nop52 PF05997.7 EGG04360.1 - 1.3e-57 194.7 0.1 1.3e-56 191.4 0.0 2.2 1 1 0 1 1 1 1 Nucleolar protein,Nop52 DPM2 PF07297.7 EGG04361.1 - 1.6e-24 85.9 0.2 2e-24 85.6 0.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EGG04361.1 - 4.3e-07 29.5 0.2 5.2e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 PIG-P PspC PF04024.7 EGG04361.1 - 0.032 13.6 2.3 0.82 9.1 0.1 2.1 2 0 0 2 2 2 0 PspC domain DUF4229 PF14012.1 EGG04361.1 - 0.035 14.0 0.1 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Ni_hydr_CYTB PF01292.15 EGG04361.1 - 0.042 13.2 0.0 0.048 13.0 0.0 1.0 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Aa_trans PF01490.13 EGG04361.1 - 0.046 12.1 0.0 4.2 5.7 0.0 2.0 2 0 0 2 2 2 0 Transmembrane amino acid transporter protein PepSY_TM_3 PF13706.1 EGG04361.1 - 0.061 12.7 0.1 0.061 12.7 0.1 2.1 2 0 0 2 2 2 0 PepSY-associated TM helix DUF2177 PF09945.4 EGG04361.1 - 0.077 12.9 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) FixQ PF05545.6 EGG04361.1 - 0.13 11.9 1.2 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ HEAT_2 PF13646.1 EGG04363.1 - 0.024 14.9 2.2 2.5 8.4 0.0 4.9 5 1 2 7 7 7 0 HEAT repeats HEAT PF02985.17 EGG04363.1 - 0.059 13.4 4.2 41 4.6 0.0 5.9 7 0 0 7 7 7 0 HEAT repeat Tax PF02959.11 EGG04363.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 HTLV Tax DALR_1 PF05746.10 EGG04363.1 - 0.73 9.8 3.9 1.5 8.7 0.0 3.3 4 0 0 4 4 4 0 DALR anticodon binding domain SMC_N PF02463.14 EGG04364.1 - 6.5e-33 113.8 14.0 6.5e-33 113.8 9.7 2.6 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGG04364.1 - 2.4e-28 98.5 0.2 1.1e-27 96.3 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGG04364.1 - 0.00036 20.5 12.3 0.00036 20.5 8.5 3.4 2 1 0 3 3 3 1 AAA domain Reo_sigmaC PF04582.7 EGG04364.1 - 1.6 7.8 19.6 0.0089 15.2 1.3 3.7 2 2 2 4 4 4 0 Reovirus sigma C capsid protein Mod_r PF07200.8 EGG04365.1 - 3.9e-11 43.0 13.8 3.8e-09 36.6 9.6 2.1 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Peptidase_S64 PF08192.6 EGG04365.1 - 0.15 10.3 3.5 0.15 10.3 2.0 1.3 1 1 0 1 1 1 0 Peptidase family S64 DUF572 PF04502.8 EGG04367.1 - 2.9 7.0 17.2 6.5 5.8 11.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) OSCP PF00213.13 EGG04368.1 - 0.014 15.2 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit DUF4613 PF15390.1 EGG04368.1 - 0.072 11.2 2.6 0.079 11.1 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Pribosyltran PF00156.22 EGG04368.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain DUF3595 PF12166.3 EGG04368.1 - 0.17 10.6 0.8 0.18 10.6 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) BLOC1_2 PF10046.4 EGG04369.1 - 0.086 12.9 0.1 13 5.9 0.0 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mt_ATP-synt_B PF05405.9 EGG04370.1 - 0.015 14.8 0.4 0.02 14.3 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Rsbr_N PF08678.5 EGG04370.1 - 0.021 14.7 0.5 0.033 14.0 0.3 1.3 1 0 0 1 1 1 0 Rsbr N terminal DUF4294 PF14127.1 EGG04370.1 - 0.044 13.3 0.5 0.11 12.0 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4294) EF_TS PF00889.14 EGG04370.1 - 0.079 12.2 0.5 0.15 11.3 0.4 1.4 1 1 0 1 1 1 0 Elongation factor TS FlxA PF14282.1 EGG04370.1 - 0.1 12.5 0.5 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 FlxA-like protein PRP1_N PF06424.7 EGG04370.1 - 0.11 12.8 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF1975 PF09318.5 EGG04370.1 - 0.19 11.2 1.3 4.3 6.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1975) zf-C3HC4_2 PF13923.1 EGG04371.1 - 6.3e-10 38.9 8.1 1.1e-09 38.1 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGG04371.1 - 1.3e-09 37.6 6.8 2.7e-09 36.6 4.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGG04371.1 - 1.3e-08 34.3 7.2 2.3e-08 33.5 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG04371.1 - 1.7e-08 33.9 5.6 2.7e-08 33.3 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG04371.1 - 2.5e-07 30.2 6.7 4.5e-07 29.4 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGG04371.1 - 1.3e-05 24.8 4.1 3e-05 23.6 2.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGG04371.1 - 2.3e-05 24.1 7.8 4.3e-05 23.3 5.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 EGG04371.1 - 4.8e-05 22.7 4.2 8.5e-05 21.9 2.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EGG04371.1 - 0.0064 15.9 5.7 0.011 15.2 2.0 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.16 EGG04371.1 - 0.0069 16.2 3.1 0.015 15.1 2.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-Apc11 PF12861.2 EGG04371.1 - 0.015 15.0 1.7 0.029 14.2 1.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SFTA2 PF15210.1 EGG04371.1 - 0.02 14.4 0.0 0.05 13.1 0.0 1.6 1 0 0 1 1 1 0 Surfactant-associated protein 2 zf-rbx1 PF12678.2 EGG04371.1 - 0.023 14.8 2.3 0.049 13.7 1.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 EGG04371.1 - 0.025 14.3 2.6 0.13 12.0 1.8 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EGG04371.1 - 0.63 9.6 5.6 1.4 8.5 3.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TerY-C PF15616.1 EGG04371.1 - 1.6 8.7 5.1 5.7 6.8 3.6 1.8 1 1 0 1 1 1 0 TerY-C metal binding domain p450 PF00067.17 EGG04372.1 - 2.8e-45 154.7 0.0 4.5e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 4HBT_2 PF13279.1 EGG04375.1 - 4e-11 43.4 0.0 6.3e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily UPF0160 PF03690.8 EGG04376.1 - 1.2e-124 415.8 0.0 1.4e-124 415.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Pkinase PF00069.20 EGG04377.1 - 4e-06 26.1 0.0 4.3e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG04377.1 - 0.00022 20.3 0.0 0.00024 20.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Borrelia_P83 PF05262.6 EGG04378.1 - 3.7 5.6 11.5 5.1 5.2 8.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3844 PF12955.2 EGG04382.1 - 0.16 12.0 2.2 0.32 11.1 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) Dysbindin PF04440.11 EGG04384.1 - 0.012 15.3 0.0 0.014 15.1 0.0 1.0 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) Sec5 PF15469.1 EGG04385.1 - 4.6e-53 179.6 0.0 2e-52 177.5 0.0 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec5 UBN2 PF14223.1 EGG04386.1 - 0.0001 22.0 0.0 0.00029 20.6 0.0 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 EGG04386.1 - 0.0027 17.5 1.0 0.0053 16.6 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle cobW PF02492.14 EGG04387.1 - 3.1e-24 85.3 0.0 3.8e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EGG04387.1 - 0.00048 20.2 0.0 0.00065 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EGG04387.1 - 0.00067 19.5 0.1 0.0016 18.3 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EGG04387.1 - 0.0013 18.4 0.0 0.0014 18.3 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 EGG04387.1 - 0.0015 17.9 0.1 0.0035 16.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EGG04387.1 - 0.0021 17.5 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_18 PF13238.1 EGG04387.1 - 0.0036 17.5 0.0 0.0047 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGG04387.1 - 0.0063 16.5 0.1 0.01 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EGG04387.1 - 0.01 14.9 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EGG04387.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EGG04387.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein UPF0079 PF02367.12 EGG04387.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EGG04387.1 - 0.014 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EGG04387.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.13 EGG04387.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EGG04387.1 - 0.02 15.1 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EGG04387.1 - 0.023 14.6 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGG04387.1 - 0.026 13.7 0.2 0.052 12.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 EGG04387.1 - 0.043 12.6 0.1 0.056 12.2 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 EGG04387.1 - 0.049 13.3 0.1 0.087 12.5 0.0 1.8 1 1 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EGG04387.1 - 0.05 13.3 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.9 EGG04387.1 - 0.083 11.8 0.0 0.083 11.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Ras PF00071.17 EGG04387.1 - 0.13 11.6 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Ras family T2SE PF00437.15 EGG04387.1 - 0.15 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.24 EGG04388.1 - 5.5e-42 143.1 0.0 9.2e-42 142.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG04388.1 - 2.9e-22 78.3 0.0 9.3e-22 76.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Thg1C PF14413.1 EGG04389.1 - 0.0087 15.7 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain DUF4101 PF13355.1 EGG04389.1 - 0.08 13.3 0.2 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4101) zf-AN1 PF01428.11 EGG04390.1 - 5.6e-09 35.7 4.9 1.1e-08 34.7 3.4 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EGG04390.1 - 0.31 11.2 5.0 0.55 10.4 3.5 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain MRAP PF15183.1 EGG04391.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family RNA_Me_trans PF04252.8 EGG04392.1 - 0.043 13.2 0.0 0.48 9.8 0.0 2.1 2 0 0 2 2 2 0 Predicted SAM-dependent RNA methyltransferase DHDPS PF00701.17 EGG04392.1 - 0.059 11.9 0.1 0.15 10.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Peptidase_M50 PF02163.17 EGG04394.1 - 0.0058 15.5 0.0 0.018 13.9 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M50 TFIIF_alpha PF05793.7 EGG04395.1 - 6.3e-11 41.3 31.8 6.3e-11 41.3 22.0 3.5 1 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ABC2_membrane PF01061.19 EGG04396.1 - 1.8e-66 223.2 47.1 1.4e-40 138.7 10.4 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EGG04396.1 - 3e-32 111.7 0.0 1.4e-18 67.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGG04396.1 - 1.1e-16 60.3 0.0 5.2e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 CDR ABC transporter AAA_21 PF13304.1 EGG04396.1 - 1.5e-06 28.4 0.0 0.43 10.5 0.0 3.7 3 0 0 3 3 3 3 AAA domain AAA_25 PF13481.1 EGG04396.1 - 4.2e-05 23.0 0.9 0.00047 19.6 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGG04396.1 - 0.00021 21.0 0.4 0.39 10.4 0.0 3.0 3 0 0 3 3 3 2 Part of AAA domain AAA_16 PF13191.1 EGG04396.1 - 0.00021 21.3 0.8 0.054 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGG04396.1 - 0.00022 21.3 0.1 0.29 11.2 0.0 3.1 2 2 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGG04396.1 - 0.00066 18.9 1.0 0.0011 18.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Pox_RNA_Pol_19 PF05320.7 EGG04396.1 - 0.02 14.6 3.3 0.048 13.4 2.3 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit AAA_29 PF13555.1 EGG04396.1 - 0.04 13.4 1.7 0.05 13.1 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.14 EGG04396.1 - 0.075 12.4 0.8 0.26 10.7 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EGG04396.1 - 0.23 10.8 2.5 11 5.4 0.1 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family CDC45 PF02724.9 EGG04396.1 - 0.55 8.2 6.1 0.88 7.5 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EGG04396.1 - 0.63 9.2 7.5 1.1 8.5 5.2 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 EGG04396.1 - 3.7 5.3 14.2 6.5 4.5 9.8 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EGG04396.1 - 4.2 5.7 14.5 7.2 4.9 10.1 1.2 1 0 0 1 1 1 0 Daxx Family AAA_17 PF13207.1 EGG04396.1 - 4.2 8.2 5.7 0.83 10.4 0.1 2.6 3 0 0 3 3 2 0 AAA domain Frag1 PF10277.4 EGG04397.1 - 6.3e-35 120.6 18.5 7.3e-35 120.3 12.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Macoilin PF09726.4 EGG04397.1 - 1 7.5 3.5 1.5 7.0 2.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2069 PF09842.4 EGG04397.1 - 7.5 6.5 12.8 19 5.2 4.8 3.3 2 2 0 2 2 2 0 Predicted membrane protein (DUF2069) Mito_carr PF00153.22 EGG04398.1 - 1.1e-52 175.6 5.2 4.2e-18 64.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1911 PF08929.5 EGG04401.1 - 0.14 12.8 1.0 35 5.1 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1911) NPV_P10 PF05531.7 EGG04402.1 - 0.046 13.9 0.1 0.046 13.9 0.1 3.1 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein RVP PF00077.15 EGG04403.1 - 0.015 15.2 0.0 0.88 9.5 0.0 2.6 2 0 0 2 2 2 0 Retroviral aspartyl protease PAPS_reduct PF01507.14 EGG04404.1 - 1.7e-38 132.1 0.0 2.4e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Bax1-I PF01027.15 EGG04405.1 - 1.1e-32 113.3 11.6 1.2e-32 113.1 8.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Inhibitor_I9 PF05922.11 EGG04406.1 - 9.3e-05 22.9 0.0 9.3e-05 22.9 0.0 2.9 2 1 0 2 2 2 1 Peptidase inhibitor I9 TP_methylase PF00590.15 EGG04407.1 - 1.2e-14 54.5 0.0 1.6e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2810 PF10928.3 EGG04408.1 - 0.095 12.4 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2810) TPR_MLP1_2 PF07926.7 EGG04410.1 - 0.023 14.4 1.5 0.043 13.5 1.1 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 EGG04410.1 - 0.069 12.3 3.5 0.1 11.7 2.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF349 PF03993.7 EGG04410.1 - 0.11 12.7 1.8 0.31 11.2 0.0 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) IncA PF04156.9 EGG04410.1 - 0.29 10.7 2.7 0.84 9.2 2.1 1.6 2 0 0 2 2 2 0 IncA protein AAA_27 PF13514.1 EGG04410.1 - 0.38 8.3 6.4 0.48 8.0 4.5 1.1 1 0 0 1 1 1 0 AAA domain Zip PF02535.17 EGG04411.1 - 0.21 10.5 6.1 0.24 10.3 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 EGG04411.1 - 4.4 5.4 8.8 5.2 5.2 6.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Peptidase_M48 PF01435.13 EGG04413.1 - 4.9e-36 124.3 0.1 8.1e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF3828 PF12883.2 EGG04413.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) COesterase PF00135.23 EGG04414.1 - 2.9e-87 293.6 0.0 5.1e-57 193.8 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family COesterase PF00135.23 EGG04415.1 - 1.2e-90 304.8 0.0 1.6e-90 304.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGG04415.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGG04415.1 - 0.069 12.3 0.1 0.16 11.1 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family RNase_T PF00929.19 EGG04416.1 - 9.2e-21 74.8 0.0 3.1e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 Exonuclease SeqA PF03925.8 EGG04418.1 - 1.3 8.6 5.7 2.4 7.8 3.9 1.4 1 0 0 1 1 1 0 SeqA protein Macoilin PF09726.4 EGG04418.1 - 4.4 5.4 11.7 5.5 5.1 8.1 1.2 1 0 0 1 1 1 0 Transmembrane protein SOBP PF15279.1 EGG04418.1 - 8.8 6.6 29.6 12 6.2 20.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Abi PF02517.11 EGG04419.1 - 1e-13 51.1 7.2 3.9e-13 49.3 5.0 2.2 1 1 0 1 1 1 1 CAAX protease self-immunity YqzM PF14141.1 EGG04419.1 - 0.034 13.9 3.1 0.11 12.3 2.2 1.8 1 0 0 1 1 1 0 YqzM-like protein CAF1 PF04857.15 EGG04420.1 - 3.6e-62 210.0 0.0 5.6e-62 209.4 0.0 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease PsbR PF04725.7 EGG04420.1 - 0.031 14.2 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR RNase_H_2 PF13482.1 EGG04420.1 - 0.047 13.4 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 RNase_H superfamily GPI-anchored PF10342.4 EGG04421.1 - 1.5e-11 44.6 3.2 1.5e-11 44.6 2.2 2.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFIIA PF03153.8 EGG04421.1 - 0.22 11.3 7.3 0.24 11.2 5.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LCAT PF02450.10 EGG04422.1 - 3e-81 273.3 0.0 3.6e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 EGG04422.1 - 0.00047 20.1 0.0 0.0035 17.2 0.0 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG04422.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lactonase PF10282.4 EGG04423.1 - 8.5e-69 232.2 0.0 9.7e-69 232.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller TPX2 PF06886.6 EGG04424.1 - 3.4e-06 27.0 12.2 3.9e-06 26.8 8.4 1.0 1 0 0 1 1 1 1 Targeting protein for Xklp2 (TPX2) TPX2_importin PF12214.3 EGG04424.1 - 0.012 15.7 2.1 0.012 15.6 1.4 1.1 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein APG6 PF04111.7 EGG04424.1 - 0.24 10.3 4.5 0.26 10.3 3.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF501 PF04417.7 EGG04424.1 - 0.26 11.1 2.8 0.31 10.9 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF501) FliT PF05400.8 EGG04424.1 - 0.26 11.6 6.8 7.1 7.1 4.7 2.1 1 1 0 1 1 1 0 Flagellar protein FliT DUF1741 PF08427.5 EGG04424.1 - 0.44 9.9 2.2 0.5 9.7 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) Tn7_Tnp_TnsA_N PF08722.6 EGG04424.1 - 0.6 10.1 3.8 0.77 9.7 2.7 1.2 1 0 0 1 1 1 0 TnsA endonuclease N terminal DUF1204 PF06721.6 EGG04424.1 - 0.74 9.0 5.4 0.82 8.8 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Endonuc_Holl PF10107.4 EGG04424.1 - 2.2 7.9 6.1 2.6 7.7 4.2 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Peptidase_S8 PF00082.17 EGG04425.1 - 4.4e-53 180.2 8.7 5.8e-53 179.8 6.1 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGG04425.1 - 3.2e-12 46.8 0.1 6.2e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 IGPS PF00218.16 EGG04426.1 - 1.3e-82 276.7 0.0 2.5e-82 275.7 0.0 1.5 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EGG04426.1 - 2.7e-51 173.9 0.0 1.8e-46 158.2 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EGG04426.1 - 1.2e-44 152.0 0.0 2.6e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGG04426.1 - 0.00058 19.3 0.3 0.0024 17.3 0.2 2.0 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 EGG04426.1 - 0.024 14.1 0.7 0.4 10.1 0.1 2.4 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 EGG04426.1 - 0.13 11.4 0.1 0.74 9.0 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein Alpha-amylase_C PF02806.13 EGG04427.1 - 2.9e-21 75.4 0.1 6.6e-21 74.2 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EGG04427.1 - 2.1e-16 60.2 0.0 1.9e-12 47.2 0.0 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EGG04427.1 - 5.5e-16 58.3 0.0 2e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alg6_Alg8 PF03155.10 EGG04429.1 - 2.6e-130 435.4 24.4 3.1e-130 435.1 16.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF2029 PF09594.5 EGG04429.1 - 0.024 14.1 12.7 0.032 13.7 5.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2029) FSH1 PF03959.8 EGG04430.1 - 3.2e-38 131.2 0.0 3.7e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF3292 PF11696.3 EGG04431.1 - 0.0002 19.3 1.1 0.014 13.3 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3292) PRT_C PF08372.5 EGG04431.1 - 0.0025 17.3 0.1 0.0025 17.3 0.1 2.7 2 2 2 4 4 4 1 Plant phosphoribosyltransferase C-terminal KMP11 PF03037.11 EGG04431.1 - 0.074 13.6 0.3 23 5.6 0.0 2.8 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 Iso_dh PF00180.15 EGG04433.1 - 9.3e-99 330.6 0.0 1.2e-98 330.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AvrL567-A PF11529.3 EGG04434.1 - 1.6e-19 70.1 0.0 2e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Melampsora lini avirulence protein AvrL567-A CRAL_TRIO PF00650.15 EGG04435.1 - 2.5e-34 118.0 0.1 4.1e-34 117.3 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGG04435.1 - 2.8e-12 46.5 0.4 1.3e-11 44.4 0.0 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGG04435.1 - 0.0006 19.7 0.5 0.0013 18.6 0.4 1.5 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Pyridox_oxase_2 PF12766.2 EGG04436.1 - 1.7e-20 73.1 0.0 2.8e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3558 PF12079.3 EGG04436.1 - 0.0017 17.9 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) CDC14 PF08045.6 EGG04437.1 - 4.4e-24 84.9 8.4 4.6e-24 84.9 5.0 1.5 2 0 0 2 2 2 1 Cell division control protein 14, SIN component GWT1 PF06423.7 EGG04439.1 - 2 8.5 5.3 1.5 8.9 0.5 2.7 2 1 0 3 3 3 0 GWT1 zf-CCHC PF00098.18 EGG04442.1 - 0.28 11.1 4.1 0.18 11.8 1.4 1.9 2 0 0 2 2 2 0 Zinc knuckle DUF2360 PF10152.4 EGG04443.1 - 0.18 12.1 3.4 0.22 11.8 2.3 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) RNA12 PF10443.4 EGG04445.1 - 0.0069 14.9 1.2 0.99 7.8 0.0 2.2 2 0 0 2 2 2 2 RNA12 protein Arch_ATPase PF01637.13 EGG04445.1 - 0.013 15.1 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_25 PF13481.1 EGG04445.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RdRP PF05183.7 EGG04446.1 - 1.3e-58 199.1 1.7 1.1e-55 189.4 1.2 3.5 1 1 0 1 1 1 1 RNA dependent RNA polymerase MS_channel PF00924.13 EGG04448.1 - 6.3e-21 74.6 1.2 1.1e-20 73.8 0.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EGG04448.1 - 0.0026 16.9 0.1 0.0026 16.9 0.1 2.7 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.1 EGG04448.1 - 0.0098 15.7 0.0 0.0098 15.7 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EGG04448.1 - 0.055 12.8 0.2 0.055 12.8 0.2 2.1 2 0 0 2 2 2 0 EF hand FH2 PF02181.18 EGG04451.1 - 0.17 10.7 0.3 0.45 9.3 0.0 1.7 2 0 0 2 2 2 0 Formin Homology 2 Domain Senescence PF06911.7 EGG04452.1 - 8e-40 136.4 6.5 1.6e-39 135.4 4.5 1.5 1 0 0 1 1 1 1 Senescence-associated protein DUF4593 PF15263.1 EGG04454.1 - 0.052 13.4 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4593) AFG1_ATPase PF03969.11 EGG04455.1 - 1.1e-90 304.1 0.0 1.4e-88 297.1 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.1 EGG04455.1 - 0.0062 16.6 0.0 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGG04455.1 - 0.014 15.3 0.3 0.3 11.0 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EGG04455.1 - 0.025 14.7 0.0 0.2 11.8 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGG04455.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PH PF00169.24 EGG04456.1 - 0.032 14.4 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 PH domain NPV_P10 PF05531.7 EGG04459.1 - 0.2 11.9 2.0 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1910 PF08928.5 EGG04460.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) Bestrophin PF01062.16 EGG04461.1 - 2.8e-48 164.3 0.5 1.3e-24 86.6 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel TRAPP PF04051.11 EGG04462.1 - 1.6e-33 115.4 0.0 1.9e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.5 EGG04462.1 - 0.031 14.0 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Abhydrolase_3 PF07859.8 EGG04464.1 - 1.6e-06 27.8 0.0 2.2e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG04464.1 - 4.6e-06 26.4 0.0 7.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EGG04464.1 - 8.2e-05 22.1 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_1 PF00561.15 EGG04464.1 - 0.00086 18.9 0.2 0.27 10.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGG04464.1 - 0.003 16.7 0.0 1.8 7.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.6 EGG04464.1 - 0.013 15.2 0.0 0.044 13.4 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2424 PF10340.4 EGG04464.1 - 0.026 13.1 0.0 0.16 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Lipase_3 PF01764.20 EGG04464.1 - 0.055 13.0 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EGG04464.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF1749 PF08538.5 EGG04464.1 - 0.078 11.8 0.0 0.17 10.7 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) COesterase PF00135.23 EGG04464.1 - 0.08 11.6 0.0 0.25 10.0 0.0 1.7 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_6 PF12697.2 EGG04464.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Inhibitor_I53 PF11714.3 EGG04465.1 - 4.5 7.3 5.4 9.4 6.3 0.8 2.3 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Complex1_LYR_1 PF13232.1 EGG04466.1 - 0.0035 17.4 1.5 0.005 17.0 1.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Ribosomal_L17 PF01196.14 EGG04466.1 - 0.12 12.9 0.2 0.22 12.0 0.2 1.6 1 1 0 1 1 1 0 Ribosomal protein L17 TPR_14 PF13428.1 EGG04466.1 - 0.13 12.9 0.5 7.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Lactamase_B_2 PF12706.2 EGG04469.1 - 1.8e-10 40.6 0.0 1.3e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGG04469.1 - 1.6e-08 34.4 0.0 2.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Cyclin_N PF00134.18 EGG04473.1 - 6.8e-10 38.6 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EGG04473.1 - 7.1e-08 32.9 0.0 7.1e-08 32.9 0.0 1.9 2 1 0 2 2 2 1 Cyclin MutL_C PF08676.6 EGG04475.1 - 2.3e-20 72.6 0.1 9.6e-20 70.6 0.0 2.1 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EGG04475.1 - 2.2e-13 50.0 0.0 4.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGG04475.1 - 2.1e-10 40.2 0.0 3.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3669 PF12417.3 EGG04475.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Zinc finger protein Nucleoplasmin PF03066.10 EGG04476.1 - 0.00012 21.6 1.0 0.0002 20.8 0.7 1.3 1 0 0 1 1 1 1 Nucleoplasmin Sporozoite_P67 PF05642.6 EGG04476.1 - 0.00096 17.1 2.6 0.00096 17.1 1.8 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF4611 PF15387.1 EGG04476.1 - 0.0034 17.5 0.2 0.0056 16.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) TFIIF_alpha PF05793.7 EGG04476.1 - 0.071 11.4 12.7 0.098 11.0 8.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sigma70_ner PF04546.8 EGG04476.1 - 0.08 12.5 0.3 0.099 12.2 0.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 EGG04476.1 - 0.11 11.2 7.6 0.15 10.7 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 EGG04476.1 - 0.13 12.6 7.6 0.2 11.9 5.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 EGG04476.1 - 2.7 5.8 4.4 3.5 5.4 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family Tom22 PF04281.8 EGG04476.1 - 3.1 7.3 4.6 5.2 6.5 3.2 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 CDC45 PF02724.9 EGG04476.1 - 6.2 4.7 5.9 8.5 4.2 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EGG04476.1 - 7.9 5.6 10.0 14 4.7 3.9 2.0 2 0 0 2 2 2 0 NOA36 protein RXT2_N PF08595.6 EGG04476.1 - 9 6.0 5.7 14 5.4 4.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DEAD PF00270.24 EGG04477.1 - 7.9e-45 152.3 0.0 1.2e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG04477.1 - 1.4e-19 69.7 0.0 6.5e-19 67.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG04477.1 - 7.5e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EGG04477.1 - 0.0029 16.9 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain AAA_19 PF13245.1 EGG04477.1 - 0.0061 16.2 0.7 0.026 14.2 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EGG04477.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGG04477.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGG04477.1 - 0.095 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein WD40 PF00400.27 EGG04478.1 - 1.5e-09 37.3 5.9 0.016 15.1 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGG04478.1 - 0.00017 21.0 0.1 5.2 6.6 0.0 5.0 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 EGG04478.1 - 0.003 17.2 0.4 0.22 11.1 0.1 3.4 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF4613 PF15390.1 EGG04478.1 - 0.043 12.0 0.2 0.21 9.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) YfhD PF14151.1 EGG04479.1 - 0.29 11.2 2.3 0.86 9.7 1.6 1.8 1 0 0 1 1 1 0 YfhD-like protein SET PF00856.23 EGG04480.1 - 2.6e-06 27.8 0.2 5e-05 23.6 0.0 2.6 2 1 0 2 2 2 1 SET domain Alpha_kinase PF02816.13 EGG04481.1 - 7.2e-07 29.0 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family YuzL PF14115.1 EGG04481.1 - 0.11 12.8 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 YuzL-like protein DSS1_SEM1 PF05160.8 EGG04482.1 - 2.5e-15 55.9 15.0 9.3e-14 50.9 10.4 2.1 1 1 0 1 1 1 1 DSS1/SEM1 family Chal_sti_synt_N PF00195.14 EGG04482.1 - 0.14 11.3 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Abhydrolase_3 PF07859.8 EGG04483.1 - 2.3e-42 144.9 0.0 1.5e-32 112.9 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EGG04483.1 - 2.3e-09 36.3 0.0 1.2e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGG04483.1 - 0.0036 17.0 0.0 0.0089 15.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_18 PF00704.23 EGG04484.1 - 2.3e-65 221.3 0.6 2.8e-65 221.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4015 PF13200.1 EGG04484.1 - 0.052 12.4 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain DUF1876 PF08962.6 EGG04485.1 - 0.18 11.6 5.4 0.26 11.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) DUF1517 PF07466.6 EGG04485.1 - 0.36 9.7 7.4 1.4 7.7 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1517) ketoacyl-synt PF00109.21 EGG04485.1 - 0.43 10.0 2.6 1.8 8.0 0.4 1.9 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain DUF763 PF05559.6 EGG04485.1 - 5.4 5.8 6.7 6 5.7 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF763) ABC_tran PF00005.22 EGG04487.1 - 5.2e-32 111.0 0.0 1.4e-22 80.5 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGG04487.1 - 2e-09 37.8 7.6 0.00022 21.2 0.5 3.2 3 0 0 3 3 3 3 AAA domain SMC_N PF02463.14 EGG04487.1 - 1.7e-07 30.6 0.1 0.082 12.1 0.0 3.2 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EGG04487.1 - 3.3e-06 26.9 0.0 0.0028 17.5 0.0 2.9 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EGG04487.1 - 0.00025 20.4 1.0 0.001 18.5 0.0 2.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EGG04487.1 - 0.046 13.7 0.1 0.25 11.2 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EGG04487.1 - 0.088 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGG04487.1 - 0.21 11.9 3.4 0.57 10.4 0.4 2.4 2 1 0 2 2 2 0 AAA domain Phage_int_SAM_1 PF02899.12 EGG04488.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FAM91_C PF14648.1 EGG04488.1 - 0.12 11.2 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 FAM91 C-terminus HsbA PF12296.3 EGG04489.1 - 0.00042 20.1 0.0 0.00082 19.2 0.0 1.5 1 1 0 1 1 1 1 Hydrophobic surface binding protein A IRF PF00605.12 EGG04491.1 - 0.052 13.3 0.5 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor MFS_1 PF07690.11 EGG04492.1 - 1.3e-27 96.4 22.2 1.8e-26 92.7 15.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Glycohydro_20b2 PF14845.1 EGG04493.1 - 0.058 14.0 0.0 0.069 13.8 0.0 1.1 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like Glyco_hydro_20 PF00728.17 EGG04494.1 - 1.9e-47 162.1 0.3 2.1e-47 161.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain EF-hand_1 PF00036.27 EGG04495.1 - 1.5e-19 67.7 0.4 3.8e-05 22.6 0.0 4.7 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EGG04495.1 - 2.7e-18 64.1 0.2 4.1e-05 23.1 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EGG04495.1 - 2e-17 63.0 0.1 8.9e-08 32.1 0.0 2.6 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGG04495.1 - 4.2e-16 57.4 0.3 0.0083 15.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EGG04495.1 - 1.5e-12 46.8 2.5 8.4e-08 31.7 0.1 4.6 3 2 1 4 4 4 3 EF-hand domain pair ADH_zinc_N_2 PF13602.1 EGG04498.1 - 0.0017 19.2 0.0 0.0042 17.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGG04498.1 - 0.011 15.5 0.0 0.042 13.6 0.0 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGG04498.1 - 0.082 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Peptidase_A21 PF03566.8 EGG04499.1 - 0.13 10.3 1.6 0.26 9.3 1.1 1.4 1 0 0 1 1 1 0 Peptidase family A21 Rep_fac_C PF08542.6 EGG04500.1 - 6.9e-21 74.0 0.1 1.3e-19 69.9 0.0 2.4 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGG04500.1 - 3.4e-12 46.3 0.0 6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EGG04500.1 - 0.0035 17.5 0.1 0.013 15.6 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGG04500.1 - 0.012 15.6 0.2 0.053 13.5 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EGG04500.1 - 0.066 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_transf_25 PF01755.12 EGG04501.1 - 3e-14 53.1 0.1 1.1e-08 34.9 0.0 3.1 3 0 0 3 3 3 3 Glycosyltransferase family 25 (LPS biosynthesis protein) GRP PF07172.6 EGG04502.1 - 0.72 10.3 7.0 0.85 10.1 4.8 1.2 1 0 0 1 1 1 0 Glycine rich protein family MBOAT PF03062.14 EGG04503.1 - 7e-36 123.9 8.3 7e-36 123.9 5.7 1.8 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Iso_dh PF00180.15 EGG04504.1 - 2.2e-82 276.7 0.0 2.8e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Med26 PF08711.6 EGG04507.1 - 0.0093 15.4 0.1 0.022 14.2 0.1 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF3129 PF11327.3 EGG04508.1 - 8.9e-16 58.2 2.3 8.9e-16 58.2 1.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3129) Arf PF00025.16 EGG04509.1 - 5.3e-66 221.1 0.2 5.9e-66 221.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGG04509.1 - 2.3e-12 46.2 1.8 1.5e-06 27.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EGG04509.1 - 1.3e-11 44.0 0.0 1.7e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGG04509.1 - 2.2e-11 43.3 0.0 2.7e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGG04509.1 - 1.9e-09 37.0 0.0 2.1e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGG04509.1 - 4.9e-09 36.7 0.0 6.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGG04509.1 - 1.1e-08 35.0 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGG04509.1 - 1.5e-07 31.0 0.0 2e-05 24.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.14 EGG04509.1 - 0.0068 15.8 0.0 0.35 10.2 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 EGG04509.1 - 0.012 14.9 0.2 0.045 13.0 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.13 EGG04509.1 - 0.013 14.5 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_17 PF13207.1 EGG04509.1 - 0.02 15.6 0.1 0.051 14.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EGG04509.1 - 0.024 14.1 0.1 0.058 12.8 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CdhD PF03599.11 EGG04509.1 - 0.096 11.1 0.0 0.21 10.0 0.0 1.4 1 1 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit GMC_oxred_N PF00732.14 EGG04510.1 - 3.3e-53 180.7 0.0 4.3e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGG04510.1 - 2.1e-37 128.5 0.0 3.6e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EGG04510.1 - 1.2e-05 25.2 0.2 4.8e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGG04510.1 - 7.6e-05 21.7 0.2 0.00061 18.7 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EGG04510.1 - 8e-05 21.6 0.1 0.0068 15.3 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGG04510.1 - 0.00022 21.1 0.2 0.00051 19.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGG04510.1 - 0.00055 18.9 0.2 0.0011 18.0 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EGG04510.1 - 0.0026 17.8 0.1 0.037 14.0 0.1 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGG04510.1 - 0.0036 16.4 0.0 0.007 15.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EGG04510.1 - 0.033 12.6 0.1 0.052 12.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EGG04510.1 - 0.063 13.0 0.2 0.18 11.5 0.2 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glyco_hydro_26 PF02156.10 EGG04511.1 - 1.8e-17 63.7 1.9 2.4e-17 63.4 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 TatD_DNase PF01026.16 EGG04513.1 - 5.1e-49 166.7 0.0 6.7e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 EGG04513.1 - 0.017 14.7 0.0 0.24 10.9 0.0 2.3 2 0 0 2 2 2 0 Amidohydrolase DUF445 PF04286.7 EGG04514.1 - 0.053 13.0 0.5 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DTHCT PF08070.6 EGG04515.1 - 0.027 15.0 2.6 0.035 14.7 1.8 1.3 1 1 0 1 1 1 0 DTHCT (NUC029) region Glyco_transf_49 PF13896.1 EGG04516.1 - 7.3e-37 127.1 1.0 2e-29 102.6 0.0 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_hydro_20 PF00728.17 EGG04517.1 - 4e-81 272.9 0.0 5.7e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EGG04517.1 - 1.7e-13 51.3 1.5 1.2e-12 48.6 0.0 2.9 3 1 0 3 3 3 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EGG04517.1 - 4.8e-05 23.8 0.3 0.0071 16.8 0.0 3.7 2 1 1 3 3 3 1 Glycosyl hydrolase family 20, domain 2 Neugrin PF06413.6 EGG04520.1 - 1.5e-08 34.7 1.0 2.1e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 EGG04520.1 - 0.00034 20.6 0.4 0.00074 19.5 0.3 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 FeoC PF09012.5 EGG04520.1 - 0.046 13.4 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator MarR_2 PF12802.2 EGG04520.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 MarR family DUF4186 PF13811.1 EGG04520.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) Cpn60_TCP1 PF00118.19 EGG04521.1 - 2.1e-130 435.6 0.3 2.4e-130 435.4 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tom7 PF08038.7 EGG04525.1 - 2.1e-09 36.6 0.0 2.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 TOM7 family Fe-ADH PF00465.14 EGG04526.1 - 5.8e-91 304.8 0.0 6.9e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGG04526.1 - 6.6e-14 51.8 0.0 6.4e-11 42.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase U79_P34 PF03064.11 EGG04530.1 - 1.2 8.5 13.2 1.7 8.1 9.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Gag_spuma PF03276.9 EGG04530.1 - 4.4 5.5 7.6 5.5 5.1 5.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Asp_protease PF09668.5 EGG04533.1 - 2.8e-12 46.2 0.3 5e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.18 EGG04533.1 - 1.1e-06 27.9 0.0 2.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 EGG04533.1 - 0.00024 20.5 1.5 0.00064 19.1 1.1 1.8 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 EGG04533.1 - 0.00025 20.6 0.1 0.0017 17.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Mt_ATP-synt_D PF05873.7 EGG04533.1 - 0.072 12.7 0.1 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) PAPS_reduct PF01507.14 EGG04534.1 - 1.7e-25 89.8 0.0 2.3e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Peptidase_S8 PF00082.17 EGG04536.1 - 1.6e-42 145.5 5.2 2.8e-42 144.7 3.6 1.4 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EGG04536.1 - 6.3e-07 29.7 0.0 2.8e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) PA PF02225.17 EGG04536.1 - 6e-06 25.8 0.1 0.00027 20.5 0.0 2.5 2 0 0 2 2 2 1 PA domain CTNNBL PF08216.6 EGG04537.1 - 1.8e-27 95.0 0.1 1.8e-27 95.0 0.0 2.6 3 1 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 EGG04537.1 - 0.021 14.6 0.1 3.5 7.5 0.0 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF1749 PF08538.5 EGG04538.1 - 9.1e-76 254.6 0.0 1.1e-75 254.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EGG04538.1 - 7.3e-07 29.2 0.0 1.1e-06 28.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG04538.1 - 9.8e-05 22.1 0.0 0.00019 21.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EGG04538.1 - 0.0074 15.7 0.0 0.076 12.4 0.0 2.2 2 1 1 3 3 3 1 Uncharacterised conserved protein (DUF2305) PuR_N PF09182.5 EGG04538.1 - 0.017 14.7 0.0 0.08 12.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal BRCT PF00533.21 EGG04538.1 - 0.091 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Ser_hydrolase PF06821.8 EGG04538.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase ig PF00047.20 EGG04539.1 - 0.075 13.1 1.1 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 Immunoglobulin domain PetL PF05115.9 EGG04542.1 - 0.62 10.0 3.3 0.6 10.0 0.6 2.2 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) OPT PF03169.10 EGG04544.1 - 1.3e-116 390.5 32.0 1.5e-116 390.3 22.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1056 PF06341.6 EGG04544.1 - 0.12 12.4 6.1 2.9 7.9 1.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) UTP15_C PF09384.5 EGG04547.1 - 6.8e-43 145.9 0.0 1e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EGG04547.1 - 5.7e-25 86.2 13.1 1.7e-07 30.8 0.1 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat DUF3312 PF11768.3 EGG04547.1 - 3.4e-05 22.2 0.0 0.011 13.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) BBS2_Mid PF14783.1 EGG04547.1 - 0.012 15.3 0.0 3.9 7.3 0.0 3.4 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EGG04547.1 - 0.11 12.8 0.2 3.5 8.0 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain THF_DHG_CYH_C PF02882.14 EGG04548.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4218 PF13960.1 EGG04549.1 - 0.0091 15.4 0.0 0.035 13.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) DUF4211 PF13926.1 EGG04551.1 - 1.6e-13 50.3 0.0 4.1e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) WD40 PF00400.27 EGG04552.1 - 2e-06 27.4 0.1 0.002 17.9 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 EGG04552.1 - 0.03 13.3 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_3 PF13570.1 EGG04552.1 - 0.2 11.9 2.1 0.31 11.3 0.0 2.3 3 0 0 3 3 3 0 PQQ-like domain Glyco_hydro_32N PF00251.15 EGG04554.1 - 8.5e-30 104.1 4.1 1.4e-21 77.2 3.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EGG04554.1 - 2.7e-17 62.9 0.0 2.2e-16 60.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal TaqI_C PF12950.2 EGG04554.1 - 0.11 12.2 0.2 12 5.6 0.1 2.5 2 0 0 2 2 2 0 TaqI-like C-terminal specificity domain MgsA_C PF12002.3 EGG04555.1 - 2.7e-56 189.8 0.1 4.3e-56 189.2 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EGG04555.1 - 2e-12 47.4 0.0 2.3e-11 43.9 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGG04555.1 - 2e-06 27.9 1.6 0.0019 18.3 0.6 3.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGG04555.1 - 9.2e-06 25.7 3.1 0.027 14.4 0.1 3.3 2 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EGG04555.1 - 0.00029 20.5 0.0 0.00066 19.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EGG04555.1 - 0.0003 20.2 0.3 0.002 17.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGG04555.1 - 0.00036 19.6 0.7 0.14 11.1 0.0 2.7 2 1 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGG04555.1 - 0.00076 19.1 0.1 0.0027 17.4 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EGG04555.1 - 0.00094 19.0 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EGG04555.1 - 0.0012 17.6 0.1 0.047 12.4 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus ABC_tran PF00005.22 EGG04555.1 - 0.0013 19.0 0.0 0.0086 16.3 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 EGG04555.1 - 0.0015 19.2 0.6 0.01 16.6 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG04555.1 - 0.0025 18.1 0.0 0.0054 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EGG04555.1 - 0.0041 17.1 0.0 0.016 15.2 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGG04555.1 - 0.0052 15.9 0.9 0.04 13.0 0.0 2.6 1 1 2 3 3 3 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EGG04555.1 - 0.0074 15.5 0.2 3.7 6.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_33 PF13671.1 EGG04555.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EGG04555.1 - 0.018 14.4 0.1 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 EGG04555.1 - 0.024 14.2 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EGG04555.1 - 0.028 14.1 0.1 0.73 9.4 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 EGG04555.1 - 0.039 13.9 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EGG04555.1 - 0.039 13.5 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 EGG04555.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.17 EGG04555.1 - 0.093 12.9 0.0 0.41 10.8 0.0 2.2 2 1 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.13 EGG04555.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EGG04555.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGG04555.1 - 0.2 11.0 0.6 0.47 9.8 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 EGG04555.1 - 0.24 10.9 1.6 1 8.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF3635 PF12330.3 EGG04556.1 - 2.9e-05 24.0 0.0 9.4e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Nucleo_P87 PF07267.6 EGG04559.1 - 0.033 12.8 0.5 0.034 12.8 0.3 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PLA2_B PF01735.13 EGG04560.1 - 8.5e-88 294.6 0.1 1.3e-87 294.0 0.1 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.17 EGG04560.1 - 1.1e-05 25.4 0.2 3.3e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase FAR1 PF03101.10 EGG04561.1 - 5.7e-06 26.7 0.9 5.7e-06 26.7 0.6 2.3 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.6 EGG04561.1 - 0.0004 20.5 0.2 0.0004 20.5 0.1 2.5 2 0 0 2 2 2 1 Transcription factor AFT TFIID-18kDa PF02269.11 EGG04562.1 - 5.8e-12 45.2 0.1 1.7e-11 43.7 0.1 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit adh_short PF00106.20 EGG04564.1 - 1.1e-22 80.7 1.2 3.5e-22 79.0 0.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG04564.1 - 1.8e-14 54.1 0.1 2.5e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG04564.1 - 1.6e-09 37.6 0.1 2.7e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EGG04564.1 - 0.0016 18.8 0.8 0.0035 17.7 0.1 1.9 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EGG04564.1 - 0.014 14.2 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Transglut_core3 PF13471.1 EGG04564.1 - 0.07 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily THF_DHG_CYH_C PF02882.14 EGG04564.1 - 0.075 12.1 0.2 0.54 9.3 0.1 2.1 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aconitase_2_N PF06434.8 EGG04564.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus MKT1_C PF12246.3 EGG04565.1 - 7.1e-62 208.5 0.0 1.1e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EGG04565.1 - 3.4e-22 78.5 0.0 1.6e-21 76.4 0.0 2.2 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 EGG04565.1 - 4.7e-08 33.2 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EGG04565.1 - 7.3e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region Abhydrolase_5 PF12695.2 EGG04566.1 - 3.8e-13 49.4 0.0 6.3e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG04566.1 - 2.6e-11 43.8 0.0 7.7e-11 42.3 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGG04566.1 - 1.2e-06 28.2 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGG04566.1 - 7.3e-05 22.0 0.4 0.02 14.1 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.6 EGG04566.1 - 0.00094 18.9 0.0 0.0021 17.8 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EGG04566.1 - 0.0049 16.3 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 EGG04566.1 - 0.0053 16.3 0.2 0.022 14.3 0.0 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EGG04566.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Sds3 PF08598.6 EGG04569.1 - 3.6e-09 36.4 12.6 4.7e-09 36.0 7.9 1.7 1 1 0 1 1 1 1 Sds3-like Bombinin PF05298.6 EGG04569.1 - 0.028 13.8 3.5 0.042 13.3 2.2 1.4 1 1 0 1 1 1 0 Bombinin UPF0175 PF03683.8 EGG04569.1 - 0.032 13.7 1.9 0.033 13.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) AAA_23 PF13476.1 EGG04569.1 - 0.034 14.4 6.4 0.043 14.1 4.4 1.1 1 0 0 1 1 1 0 AAA domain Cut12 PF11500.3 EGG04569.1 - 0.079 12.6 5.4 0.047 13.3 1.8 1.9 2 0 0 2 2 2 0 Spindle pole body formation-associated protein Gluconate_2-dh3 PF13618.1 EGG04569.1 - 0.18 11.9 1.5 1.6 8.9 0.2 2.1 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 YlqD PF11068.3 EGG04569.1 - 0.44 10.5 3.4 0.31 11.0 0.8 1.8 2 0 0 2 2 2 0 YlqD protein Alpha_kinase PF02816.13 EGG04571.1 - 4.9e-06 26.3 0.1 7.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family HA2 PF04408.18 EGG04572.1 - 1.5e-16 60.2 0.4 1.5e-16 60.2 0.3 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGG04572.1 - 1.7e-14 53.4 0.0 4.9e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EGG04572.1 - 1.8e-10 40.6 1.4 3.6e-10 39.6 0.1 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EGG04572.1 - 1.4e-08 34.3 0.1 3.1e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGG04572.1 - 5.9e-05 23.2 0.1 0.00018 21.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGG04572.1 - 0.0043 16.7 0.2 0.061 13.0 0.0 2.7 2 1 0 2 2 2 1 Part of AAA domain T2SE PF00437.15 EGG04572.1 - 0.015 14.2 0.0 0.044 12.6 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EGG04572.1 - 0.068 12.9 0.1 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF1355 PF07090.6 EGG04572.1 - 0.12 11.7 0.0 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1355) Tyrosinase PF00264.15 EGG04573.1 - 9.8e-13 48.7 1.5 1.2e-12 48.4 1.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase LRR_4 PF12799.2 EGG04574.1 - 0.026 14.1 1.1 0.84 9.3 0.5 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) E1-E2_ATPase PF00122.15 EGG04578.1 - 2.4e-57 193.6 0.2 2.4e-57 193.6 0.1 2.5 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EGG04578.1 - 1.7e-24 87.4 0.5 3.6e-24 86.3 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGG04578.1 - 2e-14 54.2 0.1 4.1e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGG04578.1 - 5.8e-14 51.3 0.1 1.6e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGG04578.1 - 6.2e-05 22.6 0.1 0.0017 17.9 0.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Nol1_Nop2_Fmu PF01189.12 EGG04582.1 - 3.3e-17 62.7 0.0 4.5e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EGG04582.1 - 0.005 16.4 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGG04582.1 - 0.059 12.8 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RRM_1 PF00076.17 EGG04583.1 - 2.8e-14 52.5 0.0 5.1e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG04583.1 - 1e-11 44.6 0.0 1.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG04583.1 - 0.025 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 EGG04584.1 - 1.3e-36 126.1 0.1 1.5e-36 125.9 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L30 PF00327.15 EGG04585.1 - 7.4e-11 41.4 0.1 1.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e YqfQ PF14181.1 EGG04585.1 - 0.0063 16.5 0.4 0.0099 15.9 0.2 1.3 1 0 0 1 1 1 1 YqfQ-like protein TLV_coat PF00429.14 EGG04585.1 - 0.065 11.6 0.5 0.073 11.5 0.3 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) G_glu_transpept PF01019.16 EGG04586.1 - 7.4e-142 473.4 0.0 8.4e-142 473.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase SAMP PF05924.6 EGG04586.1 - 2.2 7.5 3.9 0.6 9.3 0.2 2.0 2 0 0 2 2 2 0 SAMP Motif MT-A70 PF05063.9 EGG04589.1 - 2.1e-11 43.7 0.1 6.5e-07 29.0 0.1 2.4 2 0 0 2 2 2 2 MT-A70 DUF500 PF04366.7 EGG04592.1 - 2e-40 137.1 0.0 3.4e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Ribosomal_S6e PF01092.14 EGG04593.1 - 3.3e-58 194.8 0.2 6.8e-58 193.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Barttin PF15462.1 EGG04596.1 - 0.025 14.2 1.8 0.028 14.0 1.2 1.1 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) ELFV_dehydrog PF00208.16 EGG04598.1 - 8.8e-52 176.1 0.0 1.9e-51 175.0 0.0 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EGG04598.1 - 4.6e-23 80.7 0.0 2.3e-15 55.1 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EGG04598.1 - 0.0014 18.2 0.0 0.0048 16.4 0.0 1.9 1 1 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DEAD PF00270.24 EGG04599.1 - 2.5e-44 150.7 0.0 6.9e-44 149.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG04599.1 - 3.6e-26 90.8 0.1 6.8e-26 89.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG04599.1 - 0.0025 17.6 0.0 0.0059 16.4 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EGG04599.1 - 0.21 10.6 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Fork_head PF00250.13 EGG04602.1 - 2.6e-34 117.1 0.1 5.5e-34 116.0 0.1 1.5 1 0 0 1 1 1 1 Fork head domain KRTAP PF11759.3 EGG04602.1 - 7.6 6.8 18.2 0.084 13.1 6.6 2.0 2 0 0 2 2 2 0 Keratin-associated matrix MOZ_SAS PF01853.13 EGG04604.1 - 3.9e-46 156.6 1.9 4.3e-46 156.5 1.3 1.0 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.1 EGG04604.1 - 0.07 13.2 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rap1_C PF11626.3 EGG04605.1 - 0.0002 21.1 0.1 0.00038 20.2 0.1 1.5 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Corona_nucleoca PF00937.13 EGG04605.1 - 0.00039 19.4 1.5 0.00039 19.4 1.0 1.4 2 0 0 2 2 2 1 Coronavirus nucleocapsid protein Peptidase_C97 PF05903.9 EGG04606.1 - 3.1e-36 124.4 0.0 3.5e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 EGG04607.1 - 0.00048 19.0 0.1 0.00048 18.9 0.0 1.1 1 0 0 1 1 1 1 PUL domain Exonuc_V_gamma PF04257.9 EGG04607.1 - 0.036 12.0 0.0 0.041 11.8 0.0 1.2 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit GAT PF03127.9 EGG04607.1 - 0.15 12.0 2.8 4 7.4 1.9 2.1 1 1 0 1 1 1 0 GAT domain TPR_MLP1_2 PF07926.7 EGG04608.1 - 0.017 14.8 3.7 0.04 13.6 2.6 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMCO5 PF14992.1 EGG04608.1 - 0.038 13.1 6.0 0.059 12.5 4.1 1.3 1 0 0 1 1 1 0 TMCO5 family Seryl_tRNA_N PF02403.17 EGG04608.1 - 2.1 8.3 6.9 5.7 7.0 4.8 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EGG04608.1 - 3.1 7.3 6.7 12 5.4 4.6 1.9 1 1 0 1 1 1 0 IncA protein ATP-synt_ab PF00006.20 EGG04610.1 - 1.8e-61 207.3 0.0 2.5e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGG04610.1 - 2.3e-14 53.7 0.1 4.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGG04610.1 - 5e-10 39.4 0.5 9.2e-10 38.5 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Abhydrolase_6 PF12697.2 EGG04611.1 - 4e-22 79.2 0.0 5.3e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG04611.1 - 1.3e-16 60.8 0.0 3e-16 59.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG04611.1 - 3.4e-12 46.3 0.0 4.8e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EGG04611.1 - 4.2e-05 22.3 0.0 5.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.3 EGG04611.1 - 0.00026 20.7 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EGG04611.1 - 0.00035 20.4 0.0 0.00081 19.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein UPF0227 PF05728.7 EGG04611.1 - 0.0023 17.6 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 EGG04611.1 - 0.0041 16.7 0.1 0.0088 15.6 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein DLH PF01738.13 EGG04611.1 - 0.032 13.5 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Bse634I PF07832.6 EGG04611.1 - 0.044 12.9 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Cfr10I/Bse634I restriction endonuclease Thioesterase PF00975.15 EGG04611.1 - 0.077 13.2 0.0 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 Thioesterase domain FSH1 PF03959.8 EGG04611.1 - 0.099 12.0 0.0 0.39 10.1 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Fe_dep_repr_C PF02742.10 EGG04611.1 - 0.21 11.3 0.8 0.66 9.7 0.0 2.2 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain PNPOx_C PF10590.4 EGG04613.1 - 1.8e-18 65.7 0.3 3.2e-18 64.9 0.2 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EGG04613.1 - 2.7e-18 65.7 0.0 4.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EGG04613.1 - 0.00013 22.2 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1218 PF06749.7 EGG04616.1 - 2.9 8.4 11.6 0.52 10.8 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1218) Phage-Gp8 PF09215.5 EGG04619.1 - 0.1 11.7 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Bacteriophage T4, Gp8 HTH_23 PF13384.1 EGG04620.1 - 0.00065 19.2 0.3 0.0034 16.9 0.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EGG04620.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix ArsC PF03960.10 EGG04620.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 ArsC family Isy1 PF06246.7 EGG04622.1 - 7.1e-80 268.0 0.8 1.3e-79 267.2 0.6 1.4 1 1 0 1 1 1 1 Isy1-like splicing family P22_Tail-4 PF11650.3 EGG04622.1 - 0.032 13.8 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 P22 tail accessory factor SRP19 PF01922.12 EGG04624.1 - 9.1e-19 67.8 0.0 1.4e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Hydrolase_like2 PF13246.1 EGG04625.1 - 8.5e-12 44.8 0.0 3.2e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DEAD PF00270.24 EGG04629.1 - 2e-33 115.2 2.2 5.1e-32 110.6 1.5 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG04629.1 - 9.5e-24 83.0 0.0 3.7e-23 81.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG04629.1 - 7.9e-05 22.5 1.1 0.00016 21.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EGG04629.1 - 0.00072 19.5 0.3 0.0027 17.6 0.0 2.1 3 0 0 3 3 3 1 Helicase C-terminal domain ThiF PF00899.16 EGG04630.1 - 1.1e-15 57.6 0.0 2.2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family Peptidase_M28 PF04389.12 EGG04634.1 - 1.3e-16 60.8 0.0 2.4e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EGG04634.1 - 8.5e-10 38.2 0.0 1.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EGG04634.1 - 4e-07 29.6 0.0 8.2e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EGG04634.1 - 0.0076 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EGG04634.1 - 0.016 14.4 0.4 0.028 13.6 0.0 1.5 2 0 0 2 2 2 0 Nicastrin Fis1_TPR_C PF14853.1 EGG04635.1 - 4.1e-24 84.1 0.2 6.8e-24 83.5 0.1 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EGG04635.1 - 1.6e-11 43.2 0.0 2.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EGG04635.1 - 4.8e-05 22.9 0.3 9.5e-05 22.0 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGG04635.1 - 0.023 15.0 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 EGG04635.1 - 0.056 13.5 0.1 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 EGG04635.1 - 0.094 12.7 0.4 13 6.0 0.0 2.9 3 0 0 3 3 3 0 PPR repeat TPR_16 PF13432.1 EGG04635.1 - 0.13 12.9 0.0 0.21 12.3 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.20 EGG04639.1 - 3.8e-61 206.5 2.4 4.9e-42 143.8 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGG04639.1 - 5.4e-28 97.7 0.1 4.8e-21 75.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGG04639.1 - 3.8e-05 23.5 0.5 0.008 15.9 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EGG04639.1 - 0.00022 20.3 0.1 0.00057 18.9 0.0 1.7 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 EGG04639.1 - 0.00086 18.4 0.4 0.0066 15.5 0.0 2.3 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EGG04639.1 - 0.0013 19.1 0.5 0.0032 17.9 0.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 EGG04639.1 - 0.016 14.0 0.4 0.029 13.2 0.1 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EGG04639.1 - 0.023 13.5 0.0 0.051 12.3 0.0 1.5 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EGG04639.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Med13_C PF06333.7 EGG04641.1 - 0.54 8.7 7.2 0.69 8.3 0.1 2.2 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal MPC PF03650.8 EGG04645.1 - 6.5e-37 126.1 0.7 7.2e-37 125.9 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) YrpD PF15493.1 EGG04646.1 - 0.038 13.6 0.2 0.041 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function, YrpD cobW PF02492.14 EGG04648.1 - 1.1e-34 119.4 0.0 1.4e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EGG04648.1 - 1.6e-07 30.3 0.0 0.0001 21.2 0.0 2.0 2 0 0 2 2 2 2 ArgK protein AAA_17 PF13207.1 EGG04648.1 - 0.00084 20.1 0.2 0.0017 19.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGG04648.1 - 0.0012 18.2 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 EGG04648.1 - 0.0019 18.4 0.2 0.0049 17.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EGG04648.1 - 0.0053 16.2 0.1 2.9 7.2 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 EGG04648.1 - 0.099 12.0 0.0 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EGG04648.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Pox_A32 PF04665.7 EGG04648.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein NTPase_1 PF03266.10 EGG04648.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 NTPase DSBA PF01323.15 EGG04650.1 - 0.12 11.9 0.4 0.18 11.3 0.2 1.4 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Uds1 PF15456.1 EGG04650.1 - 0.13 12.2 6.1 0.18 11.7 4.3 1.3 1 0 0 1 1 1 0 Up-regulated During Septation ERM PF00769.14 EGG04650.1 - 0.21 11.0 13.3 0.23 10.9 8.2 1.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HlyD PF00529.15 EGG04650.1 - 0.42 9.8 10.8 0.49 9.6 7.5 1.0 1 0 0 1 1 1 0 HlyD family secretion protein HHA PF05321.6 EGG04650.1 - 2.6 8.2 4.5 4.2 7.5 0.7 2.7 1 1 2 3 3 3 0 Haemolysin expression modulating protein XhlA PF10779.4 EGG04650.1 - 4.1 7.3 10.7 0.18 11.7 1.3 2.4 1 1 1 2 2 2 0 Haemolysin XhlA DUF3450 PF11932.3 EGG04650.1 - 6.7 5.8 11.8 28 3.8 8.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Pkinase PF00069.20 EGG04651.1 - 5.5e-67 225.6 0.0 7.2e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG04651.1 - 1.3e-25 89.9 0.0 2.1e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG04651.1 - 2.2e-05 23.5 0.2 0.024 13.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 EGG04651.1 - 0.00055 19.3 0.1 0.00095 18.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family AFT PF08731.6 EGG04655.1 - 0.0018 18.4 0.3 0.0048 17.0 0.2 1.7 1 0 0 1 1 1 1 Transcription factor AFT tRNA-synt_2d PF01409.15 EGG04656.1 - 0.054 12.6 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) DUF4218 PF13960.1 EGG04657.1 - 0.00032 20.1 0.1 0.0009 18.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) Dmrt1 PF12374.3 EGG04657.1 - 0.28 11.5 6.4 0.99 9.8 4.4 1.9 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 CDC37_C PF08564.5 EGG04658.1 - 0.062 13.1 3.0 0.26 11.1 2.1 2.1 1 0 0 1 1 1 0 Cdc37 C terminal domain DUF605 PF04652.11 EGG04659.1 - 7.3 5.8 33.7 0.92 8.8 8.5 2.3 2 0 0 2 2 2 0 Vta1 like DDHD PF02862.12 EGG04662.1 - 0.81 9.4 6.7 1.4 8.6 4.7 1.4 1 0 0 1 1 1 0 DDHD domain DUF2215 PF10225.4 EGG04662.1 - 10 5.5 7.7 0.38 10.1 1.4 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Ric8 PF10165.4 EGG04663.1 - 0.019 13.8 0.2 0.026 13.3 0.1 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn TPR_2 PF07719.12 EGG04663.1 - 0.058 13.3 0.3 0.18 11.7 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGG04663.1 - 0.082 12.8 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat SAP PF02037.22 EGG04664.1 - 3.1e-13 48.8 0.1 9.6e-12 44.1 0.2 2.4 2 0 0 2 2 2 1 SAP domain RRM_1 PF00076.17 EGG04664.1 - 0.00014 21.4 0.0 0.00034 20.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG04664.1 - 0.00045 20.0 0.0 0.00074 19.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG04664.1 - 0.0015 18.4 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SlyX PF04102.7 EGG04666.1 - 0.07 13.5 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 SlyX DUF2515 PF10720.4 EGG04666.1 - 0.13 11.1 0.3 0.9 8.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2515) Alpha_kinase PF02816.13 EGG04667.1 - 3.2e-05 23.6 0.4 8.2e-05 22.3 0.3 1.7 1 1 0 1 1 1 1 Alpha-kinase family Plasmodium_Vir PF05795.6 EGG04669.1 - 0.00098 18.4 1.2 0.0013 18.0 0.9 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein YqzM PF14141.1 EGG04669.1 - 0.046 13.5 0.6 0.074 12.8 0.4 1.4 1 0 0 1 1 1 0 YqzM-like protein TT_ORF2 PF02957.10 EGG04669.1 - 1.5 9.5 5.4 0.9 10.2 2.4 1.6 1 1 1 2 2 2 0 TT viral ORF2 DUF4407 PF14362.1 EGG04669.1 - 2.3 7.0 4.7 3.3 6.5 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_12 PF01670.11 EGG04673.1 - 1.8e-16 60.3 0.1 2.6e-16 59.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DEP PF00610.16 EGG04673.1 - 0.056 13.1 0.0 6.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) dCMP_cyt_deam_1 PF00383.17 EGG04675.1 - 1e-11 44.3 0.7 1.3e-11 44.0 0.5 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EGG04675.1 - 3.3e-05 23.8 0.2 0.0021 18.0 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EGG04675.1 - 0.022 14.1 4.3 0.36 10.2 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Laminin_II PF06009.7 EGG04676.1 - 0.00029 20.5 1.2 0.00073 19.3 0.8 1.6 1 0 0 1 1 1 1 Laminin Domain II DUF1814 PF08843.6 EGG04676.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) KaiC PF06745.8 EGG04676.1 - 0.1 11.7 0.3 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 KaiC HECT PF00632.20 EGG04684.1 - 3.4e-92 309.0 0.1 4.2e-92 308.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) peroxidase PF00141.18 EGG04685.1 - 2.5e-48 164.5 0.0 3.4e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DBR1 PF05011.8 EGG04686.1 - 3.5e-29 101.5 0.2 5.4e-29 100.9 0.1 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EGG04686.1 - 1.7e-10 40.6 0.3 4.4e-10 39.3 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.22 EGG04689.1 - 3e-44 150.6 0.0 3e-26 92.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGG04689.1 - 1.4e-27 96.8 24.6 4.1e-15 55.9 3.8 4.0 4 1 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 EGG04689.1 - 8.1e-14 51.3 0.0 2e-06 27.1 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGG04689.1 - 3.8e-09 36.9 1.5 0.053 13.4 0.0 4.5 3 1 0 4 4 4 2 AAA domain AAA_25 PF13481.1 EGG04689.1 - 4.1e-05 23.0 0.2 0.29 10.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGG04689.1 - 0.00032 20.8 0.5 3.9 7.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EGG04689.1 - 0.00042 19.3 0.4 0.1 11.4 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 EGG04689.1 - 0.00098 19.1 0.8 0.92 9.4 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EGG04689.1 - 0.001 19.5 0.2 0.79 10.2 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 EGG04689.1 - 0.004 16.6 0.0 0.69 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 EGG04689.1 - 0.0051 16.3 3.7 0.58 9.7 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MobB PF03205.9 EGG04689.1 - 0.015 14.9 0.0 2.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EGG04689.1 - 0.022 14.7 0.1 13 5.8 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 EGG04689.1 - 0.023 13.3 0.4 1.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 EGG04689.1 - 0.053 13.1 2.2 11 5.6 0.0 4.1 5 0 0 5 5 3 0 NACHT domain Zot PF05707.7 EGG04689.1 - 0.066 12.6 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) FtsK_SpoIIIE PF01580.13 EGG04689.1 - 0.13 11.6 0.9 4 6.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family KaiC PF06745.8 EGG04689.1 - 0.15 11.1 2.7 9.1 5.3 0.1 2.6 3 0 0 3 3 2 0 KaiC DUF87 PF01935.12 EGG04689.1 - 0.17 11.6 2.6 0.41 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EGG04689.1 - 0.18 12.1 2.8 5 7.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGG04689.1 - 0.2 11.9 1.4 1.5 9.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EGG04689.1 - 0.23 11.6 1.5 28 4.9 0.2 3.5 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EGG04689.1 - 0.24 10.8 2.2 1.7 8.0 0.5 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EGG04689.1 - 0.26 12.1 4.3 0.92 10.3 0.9 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EGG04689.1 - 0.64 8.9 0.2 20 4.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.18 EGG04689.1 - 1.1 9.0 2.3 3.8 7.2 0.2 2.3 2 0 0 2 2 2 0 Dynamin family Pet127 PF08634.5 EGG04691.1 - 3e-74 249.6 2.1 4.3e-60 203.2 0.3 2.3 1 1 1 2 2 2 2 Mitochondrial protein Pet127 Ndc1_Nup PF09531.5 EGG04691.1 - 1 7.6 4.3 1.8 6.8 3.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GHL15 PF14885.1 EGG04692.1 - 0.082 13.1 0.8 0.15 12.2 0.5 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 Ribosomal_S13_N PF08069.7 EGG04695.1 - 2.2e-29 101.0 0.1 4e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EGG04695.1 - 2.6e-22 78.3 0.5 4.7e-22 77.5 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 PAX PF00292.13 EGG04695.1 - 0.024 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain YflT PF11181.3 EGG04695.1 - 0.092 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Heat induced stress protein YflT CutC PF03932.9 EGG04696.1 - 5.9e-43 146.4 0.8 4.3e-22 78.3 0.1 2.2 1 1 1 2 2 2 2 CutC family His_Phos_2 PF00328.17 EGG04697.1 - 1.9e-76 257.6 0.0 2.3e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EGG04697.1 - 1.8e-08 34.1 0.0 3.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF619 PF04768.8 EGG04698.1 - 1.5e-32 112.3 0.1 1.8e-21 76.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF619) Mit_KHE1 PF10173.4 EGG04699.1 - 2.7e-49 167.5 4.8 2.7e-49 167.5 3.4 1.7 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Ldh_1_N PF00056.18 EGG04701.1 - 3.8e-44 149.9 0.1 5.5e-44 149.4 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EGG04701.1 - 3.7e-41 140.7 0.0 5.4e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EGG04701.1 - 0.0002 20.1 0.0 0.00033 19.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EGG04701.1 - 0.032 13.5 0.1 0.28 10.4 0.1 2.1 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase VLPT PF07122.6 EGG04702.1 - 0.098 12.3 0.8 0.17 11.5 0.5 1.4 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) SNF2_N PF00176.18 EGG04703.1 - 1.1e-44 152.4 0.6 1.3e-44 152.2 0.4 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGG04703.1 - 3.9e-08 32.9 0.0 4.6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGG04703.1 - 0.0019 18.0 0.0 0.0029 17.4 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGG04704.1 - 2.2e-13 49.8 0.0 4.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoU_div PF01865.11 EGG04705.1 - 0.085 12.0 4.3 0.82 8.7 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function DUF47 TetR PF13972.1 EGG04705.1 - 0.2 11.1 1.0 0.32 10.4 0.1 1.8 2 0 0 2 2 2 0 Bacterial transcriptional repressor Gemini_C4 PF01492.12 EGG04705.1 - 0.23 11.2 11.5 1.9 8.2 1.4 3.3 3 0 0 3 3 3 0 Geminivirus C4 protein Chorion_2 PF03964.10 EGG04705.1 - 4.5 7.8 7.6 1.4 9.5 0.2 2.9 2 1 0 2 2 2 0 Chorion family 2 Apt1 PF10351.4 EGG04706.1 - 3.7e-74 250.2 1.9 6e-74 249.5 0.0 2.4 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EGG04706.1 - 6.8e-49 166.5 1.0 3.2e-34 118.1 0.0 2.4 2 0 0 2 2 2 2 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EGG04706.1 - 1e-42 145.6 0.0 2.1e-42 144.6 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EGG04706.1 - 3.8e-30 104.7 0.0 8.8e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EGG04706.1 - 4.5e-15 55.9 0.0 2.6e-14 53.5 0.0 2.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Ribonuc_red_sm PF00268.16 EGG04707.1 - 3.5e-119 396.9 0.4 4.1e-119 396.7 0.3 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain ECH PF00378.15 EGG04709.1 - 2.3e-26 92.4 0.0 6.1e-26 91.0 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family hDGE_amylase PF14701.1 EGG04710.1 - 1.2e-169 564.6 0.0 2.2e-169 563.8 0.0 1.4 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EGG04710.1 - 4.4e-110 367.8 0.0 6.4e-110 367.3 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EGG04710.1 - 2.8e-79 265.9 0.0 4.6e-79 265.2 0.0 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EGG04710.1 - 1.6e-20 72.7 0.0 3.5e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha_kinase PF02816.13 EGG04713.1 - 4.8e-08 32.8 0.6 7.9e-08 32.1 0.4 1.4 1 0 0 1 1 1 1 Alpha-kinase family DUF98 PF01947.11 EGG04716.1 - 0.054 13.2 0.1 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF98) Mito_carr PF00153.22 EGG04717.1 - 4.5e-34 116.0 1.1 1.4e-19 69.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein TFIIS_C PF01096.13 EGG04718.1 - 4.8e-19 67.7 12.8 6.7e-19 67.2 3.1 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGG04718.1 - 2.6e-09 36.5 1.2 2.6e-09 36.5 0.8 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EGG04718.1 - 1.3e-05 24.9 5.9 0.0014 18.3 0.4 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EGG04718.1 - 0.013 15.4 9.2 4.7 7.2 0.1 4.0 4 0 0 4 4 4 0 Zinc ribbon domain DUF2387 PF09526.5 EGG04718.1 - 0.029 14.2 4.2 0.15 11.9 0.1 2.2 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Lar_restr_allev PF14354.1 EGG04718.1 - 0.037 14.3 4.0 2.2 8.6 0.2 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.2 EGG04718.1 - 0.047 13.5 0.6 0.047 13.5 0.4 2.4 2 1 0 2 2 2 0 Double zinc ribbon WRKY PF03106.10 EGG04718.1 - 0.071 12.9 0.7 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 WRKY DNA -binding domain DUF2752 PF10825.3 EGG04718.1 - 0.082 12.9 0.0 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) Rep_fac-A_C PF08646.5 EGG04718.1 - 0.084 12.5 0.4 0.084 12.5 0.2 2.1 1 1 1 2 2 2 0 Replication factor-A C terminal domain IBR PF01485.16 EGG04718.1 - 0.11 12.4 0.6 0.11 12.4 0.4 2.8 2 1 0 2 2 2 0 IBR domain OrfB_Zn_ribbon PF07282.6 EGG04718.1 - 0.13 11.9 2.7 0.22 11.1 0.4 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.1 EGG04718.1 - 0.26 11.6 1.0 0.26 11.6 0.7 3.6 4 0 0 4 4 4 0 Zinc-finger double domain TerY-C PF15616.1 EGG04718.1 - 0.35 10.7 6.0 4.6 7.1 1.0 2.3 1 1 1 2 2 2 0 TerY-C metal binding domain DUF3797 PF12677.2 EGG04718.1 - 0.39 10.3 7.4 3 7.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) PADR1 PF08063.7 EGG04718.1 - 0.42 10.0 10.1 2.2 7.7 0.8 2.7 2 1 0 2 2 2 0 PADR1 (NUC008) domain HypA PF01155.14 EGG04718.1 - 0.45 10.2 4.5 3.9 7.1 3.1 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 EGG04718.1 - 0.57 10.0 6.9 0.33 10.7 0.2 2.3 2 1 1 3 3 3 0 zinc-ribbons zf-TFIIB PF13453.1 EGG04718.1 - 0.9 8.7 10.4 0.13 11.5 1.2 2.5 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-ISL3 PF14690.1 EGG04718.1 - 1 9.4 5.1 20 5.2 0.0 2.9 2 1 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C4_Topoisom PF01396.14 EGG04718.1 - 2.1 7.9 10.8 0.46 10.0 1.0 2.7 2 2 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger TF_Zn_Ribbon PF08271.7 EGG04718.1 - 3.2 7.1 8.1 4.7 6.6 0.2 2.7 2 2 0 2 2 2 0 TFIIB zinc-binding PH_10 PF15411.1 EGG04719.1 - 0.13 12.4 0.1 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain BRCT PF00533.21 EGG04720.1 - 2.6e-22 78.7 3.3 1.8e-08 34.3 0.0 5.8 5 1 1 6 6 6 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGG04720.1 - 1.2e-14 53.9 2.2 2.4e-06 27.2 0.0 4.5 5 0 0 5 5 5 2 twin BRCT domain Tox-REase-2 PF15646.1 EGG04725.1 - 0.87 9.4 7.6 0.97 9.3 1.6 2.4 1 1 0 2 2 2 0 Restriction endonuclease fold toxin 2 SMN PF06003.7 EGG04726.1 - 0.042 12.9 0.2 0.052 12.6 0.1 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PHD PF00628.24 EGG04728.1 - 0.025 14.2 2.3 0.038 13.6 1.2 1.6 1 1 0 1 1 1 0 PHD-finger Tet_JBP PF12851.2 EGG04730.1 - 0.015 14.5 0.1 0.028 13.6 0.1 1.5 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily TMPIT PF07851.8 EGG04731.1 - 0.13 11.3 1.5 0.15 11.1 0.3 1.6 2 0 0 2 2 2 0 TMPIT-like protein CAML PF14963.1 EGG04732.1 - 0.048 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF4651 PF15513.1 EGG04732.1 - 0.09 12.2 0.0 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) SURF1 PF02104.10 EGG04734.1 - 0.38 10.5 2.2 0.32 10.7 0.1 1.7 1 1 0 2 2 2 0 SURF1 family Tmemb_cc2 PF10267.4 EGG04734.1 - 0.44 9.0 5.7 0.54 8.7 4.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Peptidase_S49_N PF08496.5 EGG04734.1 - 0.95 9.2 3.5 1.6 8.4 2.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SR-25 PF10500.4 EGG04734.1 - 7.5 5.9 18.5 13 5.1 12.9 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SNARE PF05739.14 EGG04735.1 - 2.1e-14 52.9 14.7 6.9e-14 51.2 4.5 3.2 2 1 1 3 3 3 1 SNARE domain Syntaxin PF00804.20 EGG04735.1 - 8.2e-13 48.4 9.1 7.9e-12 45.2 0.3 2.6 2 0 0 2 2 2 1 Syntaxin DUF2951 PF11166.3 EGG04735.1 - 0.00075 19.2 1.1 0.00075 19.2 0.7 3.0 3 1 1 4 4 4 1 Protein of unknown function (DUF2951) FliS PF02561.9 EGG04735.1 - 0.0037 17.0 4.8 0.086 12.6 0.2 2.8 2 1 1 3 3 3 1 Flagellar protein FliS Baculo_PEP_C PF04513.7 EGG04735.1 - 0.0041 16.9 7.6 0.027 14.2 1.5 2.4 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.16 EGG04735.1 - 0.0049 16.4 6.7 0.0049 16.4 4.6 2.4 1 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Tropomyosin_1 PF12718.2 EGG04735.1 - 0.0069 16.2 12.7 0.13 12.1 2.3 2.9 3 0 0 3 3 3 2 Tropomyosin like NPV_P10 PF05531.7 EGG04735.1 - 0.017 15.3 4.4 1.6 9.0 0.1 2.8 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein OppC_N PF12911.2 EGG04735.1 - 0.023 14.0 0.2 0.036 13.4 0.1 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Prominin PF05478.6 EGG04735.1 - 0.024 12.1 6.7 0.25 8.8 0.2 2.2 2 0 0 2 2 2 0 Prominin Use1 PF09753.4 EGG04735.1 - 0.025 14.0 11.6 0.097 12.0 8.1 1.7 1 1 1 2 2 2 0 Membrane fusion protein Use1 PBP1_TM PF14812.1 EGG04735.1 - 0.041 14.1 1.9 0.066 13.5 0.0 2.1 2 1 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF948 PF06103.6 EGG04735.1 - 0.049 13.5 14.8 0.19 11.6 0.4 3.7 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) VitD-bind_III PF09164.5 EGG04735.1 - 0.067 12.8 1.0 0.34 10.5 0.1 2.5 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Spectrin PF00435.16 EGG04735.1 - 0.084 13.1 8.6 1.4 9.1 0.2 3.1 3 1 0 3 3 3 0 Spectrin repeat Gp-FAR-1 PF05823.7 EGG04735.1 - 0.1 12.5 6.1 0.24 11.3 0.6 2.4 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) NAP PF00956.13 EGG04735.1 - 0.12 11.4 7.1 2.1 7.3 4.9 2.3 1 1 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF3106 PF11304.3 EGG04735.1 - 0.12 12.7 0.6 0.12 12.7 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) Flu_NS2 PF00601.14 EGG04735.1 - 0.21 11.8 3.5 1.6 8.9 0.1 2.7 2 1 0 2 2 2 0 Influenza non-structural protein (NS2) Spc7 PF08317.6 EGG04735.1 - 0.28 9.8 13.7 2.4 6.7 2.9 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein RasGAP_C PF03836.10 EGG04735.1 - 0.32 10.6 10.7 0.049 13.3 0.7 2.7 2 1 0 2 2 2 0 RasGAP C-terminus MtrG PF04210.8 EGG04735.1 - 0.38 10.4 2.5 3.9 7.2 0.1 2.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G LOH1CR12 PF10158.4 EGG04735.1 - 0.38 10.5 5.3 0.19 11.5 0.2 2.7 1 1 3 4 4 4 0 Tumour suppressor protein Syntaxin_2 PF14523.1 EGG04735.1 - 0.72 9.9 12.8 0.28 11.2 3.4 2.4 2 0 0 2 2 2 0 Syntaxin-like protein DUF1664 PF07889.7 EGG04735.1 - 0.74 9.6 9.8 0.25 11.1 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.6 EGG04735.1 - 1.3 8.2 14.8 0.093 12.0 1.6 2.6 1 1 1 3 3 3 0 Allexivirus 40kDa protein TBPIP PF07106.8 EGG04735.1 - 1.4 8.3 17.3 0.75 9.3 1.1 3.0 2 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Vac_Fusion PF02346.11 EGG04735.1 - 1.9 7.9 7.2 6.9 6.1 0.1 3.4 3 1 0 3 3 3 0 Chordopoxvirus fusion protein Laminin_II PF06009.7 EGG04735.1 - 2.5 7.8 14.6 0.88 9.3 2.2 3.3 2 1 1 3 3 3 0 Laminin Domain II DUF972 PF06156.8 EGG04735.1 - 5.3 7.4 15.7 6.3 7.1 1.7 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF4559 PF15112.1 EGG04735.1 - 6.5 5.8 12.2 0.82 8.7 1.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4559) DUF4094 PF13334.1 EGG04735.1 - 6.8 7.1 7.7 0.97 9.8 0.1 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF4094) Atg14 PF10186.4 EGG04735.1 - 6.9 5.5 14.6 1.5 7.6 2.8 2.9 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Phasin PF05597.6 EGG04735.1 - 8.3 6.1 10.0 0.77 9.5 0.1 3.2 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SAP18 PF06487.7 EGG04737.1 - 1.4e-25 89.4 0.0 1.9e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) FAD_binding_2 PF00890.19 EGG04738.1 - 9.4e-128 426.6 4.8 1.2e-127 426.2 3.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EGG04738.1 - 7.6e-48 161.6 0.3 1.1e-47 161.0 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EGG04738.1 - 7.7e-08 32.4 0.0 1e-05 25.5 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGG04738.1 - 4e-06 26.0 0.3 0.0051 15.9 0.0 2.7 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EGG04738.1 - 3.1e-05 23.0 0.4 0.0017 17.3 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EGG04738.1 - 3.8e-05 22.7 2.0 0.0091 14.8 1.8 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EGG04738.1 - 0.0029 16.7 0.3 0.0053 15.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGG04738.1 - 0.023 13.1 1.7 0.24 9.8 0.6 2.7 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.1 EGG04738.1 - 0.093 12.7 1.5 1.1 9.3 0.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Nop14 PF04147.7 EGG04739.1 - 0.15 9.9 14.4 0.0052 14.7 5.7 1.6 2 0 0 2 2 2 0 Nop14-like family NOA36 PF06524.7 EGG04739.1 - 2.2 7.4 14.0 3.6 6.7 9.7 1.3 1 0 0 1 1 1 0 NOA36 protein Abhydrolase_5 PF12695.2 EGG04741.1 - 6.9e-10 38.8 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG04741.1 - 5.2e-08 33.0 0.2 7.3e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PhoPQ_related PF10142.4 EGG04741.1 - 0.0017 16.8 0.0 0.003 16.0 0.0 1.4 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DUF2048 PF09752.4 EGG04741.1 - 0.031 13.1 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) KIP1 PF07765.7 EGG04741.1 - 0.14 11.9 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 KIP1-like protein ketoacyl-synt PF00109.21 EGG04744.1 - 0.038 13.4 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DUF755 PF05501.6 EGG04746.1 - 0.00048 20.1 20.5 0.00048 20.1 14.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF755) BLVR PF06375.6 EGG04746.1 - 0.053 13.3 1.9 0.092 12.5 1.3 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Pox_A12 PF04651.8 EGG04746.1 - 2.7 8.0 10.7 0.41 10.7 3.2 2.2 2 0 0 2 2 2 0 Poxvirus A12 protein SR-25 PF10500.4 EGG04746.1 - 3.7 6.9 32.6 0.034 13.5 16.9 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Miff PF05644.6 EGG04746.1 - 4.6 6.8 7.0 0.29 10.7 1.0 1.7 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff NST1 PF13945.1 EGG04746.1 - 5.1 7.1 10.7 1.7 8.6 3.8 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator RNase_H2_suC PF08615.6 EGG04747.1 - 1e-18 67.4 0.0 1.5e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Dscam_C PF12355.3 EGG04748.1 - 0.066 13.4 4.3 0.18 12.0 3.0 1.8 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Peptidase_C6 PF00851.13 EGG04748.1 - 0.098 11.2 6.5 0.14 10.7 4.5 1.2 1 0 0 1 1 1 0 Helper component proteinase Bap31 PF05529.7 EGG04748.1 - 2.5 7.5 8.2 5.3 6.4 5.7 1.6 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like HHH_2 PF12826.2 EGG04749.1 - 0.011 15.6 0.0 0.089 12.6 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF1227 PF06777.6 EGG04750.1 - 1.6e-55 186.7 0.1 3.3e-55 185.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EGG04750.1 - 1.4e-47 161.2 0.0 2.4e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EGG04750.1 - 7.4e-47 159.3 0.0 1.3e-46 158.6 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 EGG04750.1 - 3.7e-05 22.6 0.0 0.00033 19.5 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGG04750.1 - 0.00024 20.6 0.0 0.11 11.9 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EGG04750.1 - 0.013 15.3 0.0 0.34 10.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EGG04750.1 - 0.069 12.7 0.1 0.13 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EGG04750.1 - 0.14 11.1 0.0 5.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Nop16 PF09420.5 EGG04751.1 - 2.4e-28 99.2 5.5 2.8e-28 99.0 3.8 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Cyclin PF08613.6 EGG04752.1 - 5.2e-37 127.5 0.0 1.1e-36 126.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin 7tm_1 PF00001.16 EGG04753.1 - 6.6e-10 38.5 3.9 9.7e-10 38.0 2.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 EGG04753.1 - 0.00019 21.0 10.1 0.0003 20.4 4.4 2.7 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EGG04753.1 - 9.7 6.0 8.0 0.24 11.1 0.3 2.3 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF4407 PF14362.1 EGG04755.1 - 5.6 5.8 9.7 12 4.7 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.12 EGG04757.1 - 9.6e-28 97.5 0.4 9.6e-28 97.5 0.3 3.2 2 1 0 2 2 2 1 DDHD domain Lipase_2 PF01674.13 EGG04757.1 - 0.019 14.2 0.3 0.058 12.7 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 2) WWE PF02825.15 EGG04757.1 - 0.23 10.9 1.5 0.67 9.4 0.4 2.3 2 0 0 2 2 2 0 WWE domain DUF2872 PF11071.3 EGG04758.1 - 0.061 13.1 0.4 2.7 7.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2872) EAP30 PF04157.11 EGG04760.1 - 0.042 13.0 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family NAM-associated PF14303.1 EGG04760.1 - 0.15 12.3 4.2 0.28 11.4 2.9 1.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain MFS_1 PF07690.11 EGG04762.1 - 6.7e-35 120.4 11.8 6.7e-35 120.4 8.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGG04762.1 - 0.0038 16.7 5.4 0.0038 16.7 3.7 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 WD40 PF00400.27 EGG04765.1 - 8e-10 38.2 4.1 0.00054 19.7 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF1513 PF07433.6 EGG04765.1 - 0.054 12.3 0.0 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Abhydrolase_1 PF00561.15 EGG04767.1 - 7.6e-37 127.0 0.0 1.4e-36 126.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGG04767.1 - 8.5e-09 35.6 0.1 3.2e-08 33.7 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EGG04767.1 - 0.00042 20.1 0.0 0.0013 18.5 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.2 EGG04767.1 - 0.034 13.8 0.0 0.17 11.6 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family HAD PF12710.2 EGG04769.1 - 5.6e-08 33.1 0.6 1.7e-07 31.6 0.4 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGG04769.1 - 0.00015 21.4 0.8 0.00015 21.4 0.5 2.0 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EGG04769.1 - 0.011 15.0 0.2 0.046 13.0 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Cytochrom_B562 PF07361.6 EGG04769.1 - 0.09 13.1 0.3 2.5 8.5 0.1 2.5 2 0 0 2 2 2 0 Cytochrome b562 PAP2 PF01569.16 EGG04770.1 - 0.088 12.4 0.1 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 PAP2 superfamily LMBR1 PF04791.11 EGG04770.1 - 0.19 10.2 0.1 0.24 9.9 0.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Pec_lyase_C PF00544.14 EGG04771.1 - 1e-17 64.2 0.9 2.3e-17 63.1 0.6 1.5 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EGG04771.1 - 0.00041 20.1 3.1 0.00077 19.2 2.1 1.5 1 1 0 1 1 1 1 Right handed beta helix region Sirohm_synth_M PF14824.1 EGG04771.1 - 0.73 8.8 2.3 3.3 6.7 0.1 2.3 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central Pec_lyase_C PF00544.14 EGG04772.1 - 0.00047 19.6 0.2 0.003 17.0 0.0 2.0 2 0 0 2 2 2 1 Pectate lyase Peptidase_M18 PF02127.10 EGG04773.1 - 3.1e-153 510.3 0.0 3.5e-153 510.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EGG04773.1 - 0.0026 16.5 0.0 0.0094 14.7 0.0 1.8 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase HSP90 PF00183.13 EGG04775.1 - 2.1e-142 475.2 20.8 2.1e-142 475.2 14.4 2.5 1 1 1 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.1 EGG04775.1 - 4.6e-12 45.7 0.1 4.6e-12 45.7 0.1 3.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGG04775.1 - 9.8e-07 28.4 0.0 2.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF966 PF06136.8 EGG04775.1 - 0.032 13.6 22.1 0.21 10.9 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Nucleo_P87 PF07267.6 EGG04777.1 - 0.049 12.3 1.5 0.054 12.1 1.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF572 PF04502.8 EGG04778.1 - 0.27 10.4 16.5 0.31 10.1 11.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) MIP-T3 PF10243.4 EGG04778.1 - 1.9 6.8 31.7 2.4 6.5 22.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RRN3 PF05327.6 EGG04778.1 - 2.4 6.1 3.7 2.7 5.9 2.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cys_Met_Meta_PP PF01053.15 EGG04782.1 - 5.6e-54 182.9 0.0 1.8e-53 181.2 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SprT-like PF10263.4 EGG04784.1 - 0.24 11.0 1.1 0.35 10.5 0.6 1.5 1 1 1 2 2 2 0 SprT-like family NBP1 PF08537.5 EGG04785.1 - 0.048 12.8 2.8 0.055 12.6 1.9 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 DUF87 PF01935.12 EGG04785.1 - 0.13 12.0 1.2 0.17 11.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 Tox-SHH PF15652.1 EGG04785.1 - 0.3 11.6 1.7 0.42 11.2 1.2 1.3 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature DUF3584 PF12128.3 EGG04785.1 - 0.32 8.2 10.9 0.35 8.1 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4200 PF13863.1 EGG04785.1 - 1.5 8.7 11.3 2.9 7.8 7.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Mis14 PF08641.7 EGG04786.1 - 0.0007 19.6 0.1 0.0015 18.5 0.1 1.6 1 0 0 1 1 1 1 Kinetochore protein Mis14 like ASFV_J13L PF05568.6 EGG04786.1 - 0.088 12.3 0.2 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Glyoxalase_2 PF12681.2 EGG04789.1 - 5.4e-08 33.3 0.0 7.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGG04789.1 - 0.0042 17.0 0.1 0.0078 16.1 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DAD PF02109.11 EGG04792.1 - 1.1e-40 138.2 1.1 1.3e-40 137.9 0.7 1.0 1 0 0 1 1 1 1 DAD family CstA PF02554.9 EGG04792.1 - 0.058 12.0 0.0 0.058 12.0 0.0 1.0 1 0 0 1 1 1 0 Carbon starvation protein CstA DUF3129 PF11327.3 EGG04793.1 - 6.1e-21 75.0 0.2 8.2e-21 74.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) DUF3129 PF11327.3 EGG04794.1 - 2.9e-24 85.9 0.5 1.9e-23 83.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3129) LHC PF00556.15 EGG04795.1 - 0.11 12.3 1.5 0.14 12.0 0.2 1.8 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit ADH_zinc_N PF00107.21 EGG04797.1 - 0.0088 15.5 0.0 0.0088 15.5 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FliD_N PF02465.13 EGG04798.1 - 0.0019 18.5 4.8 0.0019 18.5 3.3 2.3 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 N-terminus Sec20 PF03908.8 EGG04798.1 - 0.14 11.8 2.0 0.36 10.5 0.7 2.3 2 0 0 2 2 2 0 Sec20 DUF3698 PF12479.3 EGG04798.1 - 0.31 11.1 5.9 2.2 8.4 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3698) Amidohydro_1 PF01979.15 EGG04805.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family Chlorosome_CsmC PF11098.3 EGG04807.1 - 0.26 11.0 5.3 0.4 10.3 3.7 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C Sporozoite_P67 PF05642.6 EGG04807.1 - 2.2 6.0 5.1 2.3 5.9 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SPT6_acidic PF14632.1 EGG04808.1 - 1.4 9.1 6.9 0.74 10.0 0.7 2.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 LpxD PF04613.9 EGG04810.1 - 0.11 12.0 0.2 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD DUF2743 PF10899.3 EGG04811.1 - 0.31 10.3 3.8 0.36 10.1 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2743) Nucleo_P87 PF07267.6 EGG04811.1 - 0.4 9.3 8.4 0.41 9.2 5.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DDHD PF02862.12 EGG04811.1 - 0.84 9.3 9.7 0.89 9.2 6.7 1.2 1 0 0 1 1 1 0 DDHD domain OPT PF03169.10 EGG04813.1 - 2.7e-166 554.6 40.8 3.1e-166 554.4 28.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Mito_carr PF00153.22 EGG04815.1 - 5.9e-47 157.3 0.1 5.9e-14 51.5 0.0 4.9 4 1 0 4 4 4 4 Mitochondrial carrier protein MCLC PF05934.6 EGG04816.1 - 0.19 9.9 3.1 0.33 9.1 2.2 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) NST1 PF13945.1 EGG04817.1 - 0.11 12.5 10.1 0.18 11.8 7.0 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF2718 PF10918.3 EGG04817.1 - 0.14 12.2 0.6 0.28 11.2 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2718) RNA_pol_Rpc82 PF05645.8 EGG04818.1 - 0.01 15.3 2.6 0.012 15.2 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 CDC45 PF02724.9 EGG04818.1 - 3.3 5.6 5.7 4 5.3 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1764 PF08576.5 EGG04818.1 - 9.5 7.0 9.0 47 4.8 6.3 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) zf-primase PF09329.6 EGG04819.1 - 0.56 9.8 5.0 1.9 8.1 0.0 3.6 4 0 0 4 4 4 0 Primase zinc finger Ras PF00071.17 EGG04822.1 - 0.0012 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Chlorosome_CsmC PF11098.3 EGG04824.1 - 0.26 11.0 5.3 0.4 10.3 3.7 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C Sporozoite_P67 PF05642.6 EGG04824.1 - 2.2 6.0 5.1 2.3 5.9 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen OTU PF02338.14 EGG04825.1 - 1.7e-05 25.3 0.0 3.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease FAR1 PF03101.10 EGG04825.1 - 8.3e-05 23.0 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Peptidase_C65 PF10275.4 EGG04825.1 - 0.0023 17.3 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain zf-CCHC PF00098.18 EGG04826.1 - 0.79 9.7 4.7 1.5 8.8 3.3 1.4 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.11 EGG04831.1 - 4e-23 81.7 20.7 9.4e-23 80.4 14.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1634 PF07843.6 EGG04831.1 - 0.0068 16.0 0.2 0.073 12.7 0.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1634) TRI12 PF06609.8 EGG04831.1 - 0.0073 14.5 1.2 0.011 13.9 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4064 PF13273.1 EGG04831.1 - 0.16 12.1 5.2 7.4 6.7 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) UNC-93 PF05978.11 EGG04831.1 - 1.8 8.0 10.8 0.25 10.8 2.7 2.8 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 GST_N_3 PF13417.1 EGG04834.1 - 7.3e-05 22.9 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGG04834.1 - 0.00068 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGG04834.1 - 0.013 15.9 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.13 EGG04835.1 - 5.4e-07 29.4 8.4 5.4e-07 29.4 5.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGG04835.1 - 0.00068 18.5 0.0 0.0011 17.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MerR-DNA-bind PF09278.6 EGG04835.1 - 0.0083 16.5 0.6 0.022 15.1 0.4 1.7 1 0 0 1 1 1 1 MerR, DNA binding RrnaAD PF00398.15 EGG04838.1 - 6.7e-59 199.0 0.0 8.6e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EGG04838.1 - 5.9e-09 35.9 0.0 9.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG04838.1 - 0.0001 22.8 0.0 0.00016 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG04838.1 - 0.00013 22.3 0.0 0.00023 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG04838.1 - 0.00013 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EGG04838.1 - 0.0016 18.0 0.0 0.0032 17.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG04838.1 - 0.0054 16.4 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGG04838.1 - 0.0087 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 EGG04838.1 - 0.013 14.6 0.0 0.035 13.2 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase Ubie_methyltran PF01209.13 EGG04838.1 - 0.023 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EGG04838.1 - 0.034 13.5 0.0 0.067 12.5 0.0 1.5 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.6 EGG04838.1 - 0.041 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.7 EGG04838.1 - 0.09 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Pkinase PF00069.20 EGG04839.1 - 1.4e-08 34.1 0.4 1.6e-08 34.0 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG04839.1 - 0.0069 15.4 0.2 0.0069 15.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase GTP_cyclohydro2 PF00925.15 EGG04840.1 - 7.9e-56 187.9 0.0 2.3e-54 183.1 0.0 2.0 1 1 0 1 1 1 1 GTP cyclohydrolase II F-box-like PF12937.2 EGG04842.1 - 5.3e-05 22.8 1.9 0.00026 20.6 0.0 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EGG04842.1 - 0.03 13.9 1.2 1.1 9.0 0.2 3.3 2 1 0 2 2 2 0 F-box domain UCH PF00443.24 EGG04845.1 - 9.3e-47 159.3 0.0 1.6e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGG04845.1 - 6.8e-24 83.7 19.3 8.6e-19 67.4 4.3 3.1 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EGG04845.1 - 7.9e-21 74.7 0.0 8.1e-20 71.4 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EGG04845.1 - 3.6e-16 58.4 0.0 1e-07 31.5 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain DUF3173 PF11372.3 EGG04845.1 - 0.059 12.9 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) Dicty_REP PF05086.7 EGG04848.1 - 0.32 8.7 2.1 0.59 7.8 1.4 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DDE_Tnp_4 PF13359.1 EGG04849.1 - 3.3e-24 85.2 0.0 4.6e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease UCH PF00443.24 EGG04853.1 - 0.039 13.0 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Nup160 PF11715.3 EGG04854.1 - 1.3e-43 148.9 9.6 2.3e-43 148.1 6.6 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoplasmin PF03066.10 EGG04854.1 - 0.11 12.0 4.9 2.2 7.8 0.6 2.4 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EGG04854.1 - 7.1 6.9 9.3 6.7 7.0 1.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CTX_RstB PF07459.6 EGG04856.1 - 0.0081 16.0 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 CTX phage RstB protein FlgD PF03963.9 EGG04857.1 - 0.091 12.8 0.8 0.091 12.8 0.6 1.8 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region Pox_Ag35 PF03286.9 EGG04857.1 - 0.094 12.2 5.5 0.12 11.8 3.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 EGG04857.1 - 0.7 7.8 4.1 0.83 7.6 2.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGG04857.1 - 3.7 5.3 10.4 4.3 5.1 7.2 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2413 PF10310.4 EGG04858.1 - 0.4 9.4 20.9 0.68 8.6 14.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Hid1 PF12722.2 EGG04858.1 - 5.8 4.4 17.6 7.2 4.1 12.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.4 EGG04858.1 - 6 5.0 17.2 7.9 4.6 11.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Asp-B-Hydro_N PF05279.6 EGG04858.1 - 8.7 6.1 13.0 12 5.6 9.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Fungal_trans PF04082.13 EGG04863.1 - 3.2e-21 75.4 0.0 1.7e-19 69.6 0.0 2.6 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGG04863.1 - 2.1e-05 24.3 4.3 4.4e-05 23.3 3.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_8 PF05148.10 EGG04864.1 - 1.5e-51 175.1 2.4 3.5e-28 98.7 1.6 3.3 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EGG04864.1 - 0.0059 17.0 0.1 0.074 13.5 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain LNS2 PF08235.8 EGG04865.1 - 1.2e-71 239.3 0.0 3.6e-71 237.8 0.0 1.8 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EGG04865.1 - 2.8e-30 104.2 0.0 4.2e-20 71.4 0.0 2.5 2 0 0 2 2 2 2 lipin, N-terminal conserved region OspD PF03207.8 EGG04867.1 - 0.051 12.7 0.2 0.087 11.9 0.1 1.3 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) IL10 PF00726.12 EGG04868.1 - 0.042 13.1 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Interleukin 10 Helicase_C PF00271.26 EGG04868.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain TATR PF03430.8 EGG04869.1 - 0.13 10.8 4.1 0.16 10.5 2.8 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF4629 PF15442.1 EGG04869.1 - 0.15 12.1 7.9 0.22 11.6 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) GF_recep_IV PF14843.1 EGG04870.1 - 0.069 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Growth factor receptor domain IV DUF742 PF05331.6 EGG04870.1 - 0.16 11.5 2.6 0.32 10.5 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF742) IlvC PF01450.14 EGG04871.1 - 0.0088 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain YEATS PF03366.11 EGG04872.1 - 1.7e-29 101.3 0.3 3.6e-29 100.2 0.1 1.6 2 0 0 2 2 2 1 YEATS family PLA2_B PF01735.13 EGG04873.1 - 3e-75 253.2 1.3 2.7e-72 243.5 0.9 2.2 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Lyase_aromatic PF00221.14 EGG04875.1 - 3.4e-150 500.5 3.0 4.1e-150 500.3 2.1 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Prefoldin PF02996.12 EGG04876.1 - 0.041 13.5 1.6 2.3 7.8 0.4 2.2 2 0 0 2 2 2 0 Prefoldin subunit NPV_P10 PF05531.7 EGG04876.1 - 1.2 9.3 3.5 3.8 7.8 0.2 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 EGG04876.1 - 2.9 7.7 10.1 4.4 7.1 2.9 2.3 1 1 0 2 2 2 0 Tropomyosin like PhoD PF09423.5 EGG04877.1 - 2.8e-52 177.7 0.1 3.6e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase DUF3535 PF12054.3 EGG04881.1 - 1.1e-82 278.1 0.2 1.1e-81 274.6 0.0 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EGG04881.1 - 5.9e-72 241.9 0.1 8.3e-72 241.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EGG04881.1 - 3.9e-13 48.2 13.8 0.91 9.7 0.0 9.3 9 0 0 9 9 9 6 HEAT repeat Helicase_C PF00271.26 EGG04881.1 - 6.9e-12 45.0 0.0 1.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 EGG04881.1 - 0.0002 21.6 0.0 0.23 11.8 0.0 3.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EGG04881.1 - 0.00031 20.9 11.5 0.01 16.1 0.1 6.4 5 2 2 7 7 7 1 HEAT repeats HEAT_EZ PF13513.1 EGG04881.1 - 0.0036 17.7 18.7 17 6.0 0.0 9.8 8 2 2 10 10 10 1 HEAT-like repeat Nuf2 PF03800.9 EGG04882.1 - 3.1e-10 40.2 0.1 3.1e-10 40.2 0.0 2.2 2 1 0 2 2 2 1 Nuf2 family ING PF12998.2 EGG04882.1 - 0.021 15.0 26.1 0.11 12.7 2.0 3.2 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Utp12 PF04003.7 EGG04882.1 - 0.11 12.3 2.3 6 6.8 0.2 3.2 3 1 0 3 3 3 0 Dip2/Utp12 Family Baculo_PEP_C PF04513.7 EGG04882.1 - 0.17 11.7 11.9 0.07 12.9 1.8 3.7 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EGG04882.1 - 0.69 9.0 7.1 0.55 9.3 0.4 2.5 1 1 2 3 3 3 0 Reovirus sigma C capsid protein WEMBL PF05701.6 EGG04882.1 - 0.91 7.9 34.1 1.3 7.4 23.7 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Tweety PF04906.8 EGG04882.1 - 5.4 5.3 9.2 8.5 4.6 0.6 2.5 1 1 1 2 2 2 0 Tweety DUF4610 PF15384.1 EGG04884.1 - 0.00054 19.5 2.4 0.93 8.9 0.1 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4610) Imm13 PF15564.1 EGG04884.1 - 0.009 15.7 1.3 0.8 9.4 0.0 3.9 4 1 1 5 5 5 1 Immunity protein 13 PXT1 PF15214.1 EGG04884.1 - 0.025 14.8 1.1 0.84 9.9 0.1 3.0 3 0 0 3 3 3 0 Peroxisomal testis-specific protein 1 KRTAP PF11759.3 EGG04884.1 - 2.7 8.2 17.0 8 6.7 4.7 2.4 2 0 0 2 2 2 0 Keratin-associated matrix DUF1681 PF07933.9 EGG04886.1 - 8.9e-57 191.1 0.0 1e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) zf-RING_4 PF14570.1 EGG04888.1 - 0.82 9.2 7.2 0.35 10.4 1.6 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGG04888.1 - 2.4 8.1 10.1 1.1 9.1 3.9 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4610 PF15384.1 EGG04889.1 - 0.0036 16.8 0.2 0.1 12.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4610) Reo_sigmaC PF04582.7 EGG04889.1 - 0.079 12.1 7.4 0.042 13.0 1.4 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Gly-zipper_OmpA PF13436.1 EGG04889.1 - 3.2 7.4 14.0 7.3 6.2 9.7 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 EGG04889.1 - 8.9 6.5 16.5 2.8 8.1 8.3 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide C1-set PF07654.10 EGG04891.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.5 2 0 0 2 2 2 0 Immunoglobulin C1-set domain PC-Esterase PF13839.1 EGG04893.1 - 3.6e-06 26.9 0.0 6e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p zf-DHHC PF01529.15 EGG04894.1 - 4.6e-39 133.5 0.6 4.6e-39 133.5 0.4 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF3816 PF12822.2 EGG04894.1 - 0.015 15.2 5.5 0.015 15.2 3.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) DUF962 PF06127.6 EGG04895.1 - 5.7e-26 90.2 2.6 8.5e-26 89.6 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) DUF1056 PF06341.6 EGG04895.1 - 0.34 10.9 0.2 0.34 10.9 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1056) DUF2417 PF10329.4 EGG04895.1 - 0.58 9.5 6.6 0.37 10.1 2.1 2.0 2 0 0 2 2 2 0 Region of unknown function (DUF2417) RDD PF06271.7 EGG04895.1 - 7.8 6.3 12.9 0.42 10.5 1.1 2.4 1 1 1 2 2 2 0 RDD family FTR1 PF03239.9 EGG04896.1 - 3.8e-54 183.7 7.7 1.5e-53 181.7 5.3 1.7 1 1 0 1 1 1 1 Iron permease FTR1 family Herpes_glycop PF01528.11 EGG04896.1 - 0.0025 16.5 0.0 0.0025 16.5 0.0 2.0 2 0 0 2 2 2 1 Herpesvirus glycoprotein M ABC2_membrane_2 PF12679.2 EGG04896.1 - 0.018 13.8 12.2 0.13 11.1 2.1 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein GWT1 PF06423.7 EGG04896.1 - 0.13 12.3 2.9 0.35 10.9 0.0 2.8 3 0 0 3 3 3 0 GWT1 DUF3671 PF12420.3 EGG04896.1 - 0.31 11.0 0.1 0.31 11.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function tRNA-synt_2b PF00587.20 EGG04898.1 - 2.6e-46 157.3 0.0 4.1e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGG04898.1 - 9.9e-18 63.8 0.1 1.8e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EGG04898.1 - 4.1e-13 48.9 0.0 9.1e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EGG04898.1 - 7.7e-06 25.6 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain PNP_UDP_1 PF01048.15 EGG04899.1 - 2.3e-26 92.2 0.0 3e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF1713 PF08213.6 EGG04900.1 - 0.056 13.0 5.8 0.12 11.9 4.1 1.6 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) Asp PF00026.18 EGG04901.1 - 5.6e-52 176.9 0.7 3.5e-45 154.6 0.3 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG04901.1 - 6.4e-10 39.2 0.4 1.4e-08 34.8 0.5 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGG04901.1 - 0.00026 21.4 0.4 0.47 10.9 0.0 3.3 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 EGG04901.1 - 0.0069 16.1 0.0 0.71 9.7 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF3443 PF11925.3 EGG04901.1 - 0.027 13.1 0.3 0.045 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) Piwi PF02171.12 EGG04902.1 - 4.4e-59 199.9 0.0 7.1e-59 199.2 0.0 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EGG04902.1 - 0.0045 16.2 0.1 0.01 15.1 0.1 1.6 1 0 0 1 1 1 1 PAZ domain GPI-anchored PF10342.4 EGG04905.1 - 2.3e-08 34.4 0.1 2.3e-08 34.4 0.1 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AAA PF00004.24 EGG04906.1 - 1.1e-40 138.8 0.0 2.5e-40 137.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGG04906.1 - 4.8e-05 23.4 0.1 0.0029 17.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EGG04906.1 - 0.00026 20.1 0.1 0.00059 18.9 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EGG04906.1 - 0.00026 20.7 0.2 0.0031 17.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGG04906.1 - 0.00054 20.1 0.5 0.018 15.1 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGG04906.1 - 0.00074 19.4 0.7 0.0083 16.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EGG04906.1 - 0.002 17.3 0.1 0.012 14.8 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 EGG04906.1 - 0.0032 17.3 0.0 0.008 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGG04906.1 - 0.005 16.0 0.5 0.016 14.4 0.0 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EGG04906.1 - 0.005 16.2 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EGG04906.1 - 0.0052 16.5 0.2 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EGG04906.1 - 0.0057 17.4 0.3 0.018 15.8 0.1 2.0 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 EGG04906.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EGG04906.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGG04906.1 - 0.016 14.3 0.8 0.092 11.8 0.0 2.3 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.7 EGG04906.1 - 0.051 12.6 0.4 0.13 11.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 EGG04906.1 - 0.055 12.8 0.8 0.49 9.7 0.1 2.3 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGG04906.1 - 0.06 12.9 1.4 0.1 12.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGG04906.1 - 0.12 12.5 0.1 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 EGG04906.1 - 0.13 11.8 0.3 2.3 7.8 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Tetraspannin PF00335.15 EGG04907.1 - 0.12 11.6 13.2 0.36 10.0 9.2 1.8 1 1 0 1 1 1 0 Tetraspanin family DUF378 PF04070.7 EGG04907.1 - 0.16 11.5 6.5 0.39 10.3 4.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF378) DUF3154 PF11351.3 EGG04907.1 - 0.19 11.4 1.3 0.32 10.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) PepSY_TM PF03929.11 EGG04907.1 - 0.65 10.5 11.3 0.27 11.7 0.9 3.6 3 0 0 3 3 3 0 PepSY-associated TM helix PMP22_Claudin PF00822.15 EGG04907.1 - 0.69 9.5 6.5 0.39 10.3 2.9 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family Yip1 PF04893.12 EGG04907.1 - 6.7 6.1 14.3 38 3.7 10.0 2.0 1 1 1 2 2 2 0 Yip1 domain PWI PF01480.12 EGG04908.1 - 3e-08 33.6 1.4 4.2e-08 33.1 0.1 1.9 2 0 0 2 2 2 1 PWI domain TMEM192 PF14802.1 EGG04908.1 - 0.053 12.3 1.5 0.11 11.3 1.0 1.4 1 0 0 1 1 1 0 TMEM192 family GCM PF03615.10 EGG04909.1 - 0.007 15.9 2.3 0.039 13.5 0.9 2.3 2 0 0 2 2 2 1 GCM motif protein Nop14 PF04147.7 EGG04909.1 - 1.9 6.2 6.1 2.6 5.8 4.3 1.2 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_31 PF01055.21 EGG04913.1 - 2.6e-140 468.1 2.4 3.4e-140 467.7 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGG04913.1 - 1.1e-22 79.6 0.0 3.6e-22 77.9 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like PRKCSH-like PF12999.2 EGG04913.1 - 3.8e-12 46.1 5.6 6.6e-12 45.3 3.9 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like Ldl_recept_a PF00057.13 EGG04913.1 - 0.57 10.1 9.4 1.3 9.0 6.5 1.6 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Glyco_hydro_31 PF01055.21 EGG04914.1 - 1.3e-119 399.9 4.1 1.8e-119 399.5 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGG04914.1 - 1.9e-25 88.4 0.2 7.5e-24 83.3 0.0 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like PRKCSH_1 PF13015.1 EGG04915.1 - 2.1e-28 98.7 0.4 2.1e-28 98.7 0.3 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.2 EGG04915.1 - 2.6e-16 59.7 2.8 2.6e-16 59.7 1.9 2.2 2 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH PF07915.8 EGG04915.1 - 8.5e-06 26.4 3.2 8.5e-06 26.4 2.2 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 EGG04915.1 - 0.47 10.4 10.2 1.4 8.8 7.1 1.9 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A HALZ PF02183.13 EGG04915.1 - 0.77 9.5 8.4 0.34 10.6 0.1 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 EGG04915.1 - 0.99 9.3 8.5 0.21 11.4 0.4 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) AA_permease PF00324.16 EGG04916.1 - 3.5e-120 401.5 36.2 4.4e-120 401.2 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGG04916.1 - 1.1e-32 113.1 38.9 1.4e-32 112.7 27.0 1.2 1 0 0 1 1 1 1 Amino acid permease Ank_4 PF13637.1 EGG04918.1 - 2.4e-14 53.3 0.3 1e-07 32.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGG04918.1 - 3.6e-14 52.8 0.0 4.7e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGG04918.1 - 9.9e-13 47.8 0.1 1.2e-08 34.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EGG04918.1 - 2.2e-11 42.9 0.1 7.2e-07 28.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EGG04918.1 - 3e-09 36.2 0.0 0.00016 21.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat SH3_1 PF00018.23 EGG04919.1 - 2.5e-14 52.3 0.0 9.5e-09 34.5 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EGG04919.1 - 1.6e-10 40.3 0.0 0.00029 20.3 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 EGG04919.1 - 1.3e-06 27.7 0.0 0.005 16.2 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain DEAD PF00270.24 EGG04920.1 - 1.6e-10 40.7 0.0 5.8e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG04920.1 - 0.002 17.9 0.0 0.016 15.0 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain CRAL_TRIO PF00650.15 EGG04921.1 - 4.2e-40 136.8 0.4 7.8e-40 135.9 0.3 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EGG04921.1 - 2.7e-13 50.0 0.0 4.7e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGG04921.1 - 3.1e-07 30.4 1.0 9.6e-07 28.8 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Mito_carr PF00153.22 EGG04923.1 - 8.5e-57 188.8 2.8 1.2e-21 76.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Med26 PF08711.6 EGG04924.1 - 0.00089 18.7 0.4 0.0025 17.2 0.1 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Tho2 PF11262.3 EGG04925.1 - 2.3e-56 191.0 0.0 1.4e-55 188.4 0.0 2.3 1 1 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EGG04925.1 - 2.2e-26 91.4 0.1 6.3e-26 89.9 0.1 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit IncA PF04156.9 EGG04926.1 - 0.058 12.9 0.3 4 6.9 0.0 2.0 2 0 0 2 2 2 0 IncA protein Ribosomal_S25 PF03297.10 EGG04929.1 - 1.8e-39 133.9 4.3 2.2e-39 133.7 3.0 1.1 1 0 0 1 1 1 1 S25 ribosomal protein DUF505 PF04458.7 EGG04929.1 - 0.0021 16.2 0.0 0.0024 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF505) HTH_24 PF13412.1 EGG04929.1 - 0.016 14.5 0.2 0.028 13.7 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MerR_1 PF13411.1 EGG04929.1 - 0.068 12.9 0.1 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 MerR HTH family regulatory protein Ftsk_gamma PF09397.5 EGG04929.1 - 0.081 12.6 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Ftsk gamma domain MarR PF01047.17 EGG04929.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 MarR family Spc24 PF08286.6 EGG04930.1 - 0.12 12.0 1.4 0.24 11.1 0.8 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 NTF2 PF02136.15 EGG04931.1 - 1.4e-05 25.4 0.0 2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Lumazine_bd PF12870.2 EGG04931.1 - 0.0029 17.6 1.5 0.0065 16.5 1.0 1.7 1 1 0 1 1 1 1 Lumazine-binding domain Lumazine_bd_2 PF12893.2 EGG04931.1 - 0.019 15.5 0.0 0.027 15.0 0.0 1.2 1 0 0 1 1 1 0 Putative lumazine-binding Ras PF00071.17 EGG04932.1 - 2.5e-46 157.0 0.0 4.5e-46 156.2 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGG04932.1 - 1.1e-19 71.0 0.0 2.3e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG04932.1 - 2.4e-15 56.2 0.0 3.9e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGG04932.1 - 2e-06 27.1 0.0 2.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGG04932.1 - 2e-05 23.8 0.0 4.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGG04932.1 - 0.00066 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGG04932.1 - 0.0087 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EGG04932.1 - 0.13 11.7 0.3 7.3 6.0 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RAP1 PF07218.6 EGG04933.1 - 1.3 6.9 3.5 1.6 6.6 2.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Nanovirus_coat PF04660.7 EGG04943.1 - 0.049 13.3 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Nanovirus coat protein FAM72 PF14976.1 EGG04947.1 - 1.6e-20 73.4 0.9 3.1e-20 72.5 0.6 1.4 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.9 EGG04947.1 - 0.031 14.3 8.9 8 6.5 0.0 3.2 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Transpos_assoc PF13963.1 EGG04947.1 - 0.069 13.1 1.8 0.15 12.0 1.3 1.6 1 0 0 1 1 1 0 Transposase-associated domain Peptidase_C1_2 PF03051.10 EGG04948.1 - 2.1e-152 507.7 0.0 9.2e-152 505.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EGG04948.1 - 0.00011 22.1 0.1 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.8 EGG04948.1 - 0.08 11.4 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family Peptidase_C1_2 PF03051.10 EGG04949.1 - 1.3e-158 528.1 0.1 4.8e-158 526.2 0.1 1.7 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EGG04949.1 - 2.1e-05 24.4 0.1 0.16 11.7 0.0 2.6 2 1 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EGG04950.1 - 3.4e-137 457.5 0.0 2e-136 455.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase C1-like family DUF1661 PF07877.6 EGG04950.1 - 0.036 13.5 0.5 0.036 13.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) Peptidase_C1_2 PF03051.10 EGG04951.1 - 2.9e-124 414.9 0.0 8e-124 413.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase C1-like family zf-4CXXC_R1 PF10497.4 EGG04951.1 - 0.11 12.5 16.4 0.26 11.4 11.0 1.8 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 F-box-like PF12937.2 EGG04952.1 - 0.00041 20.0 1.4 0.007 16.0 1.0 2.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EGG04952.1 - 0.078 12.6 1.5 0.27 10.9 0.5 2.4 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.2 EGG04952.1 - 0.12 11.9 0.3 4.2 7.0 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF1279 PF06916.8 EGG04953.1 - 4.4 7.6 6.3 12 6.3 2.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1279) zf-UBR PF02207.15 EGG04954.1 - 1e-15 57.1 19.6 1e-15 57.1 13.6 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EGG04954.1 - 2.9e-12 46.1 0.1 2.8e-10 39.7 0.0 2.6 2 0 0 2 2 2 2 ATP-dependent Clp protease adaptor protein ClpS Cu-oxidase_3 PF07732.10 EGG04955.1 - 3.6e-45 152.4 1.6 7.1e-43 145.0 0.4 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG04955.1 - 2.7e-30 104.6 2.4 1.3e-24 86.2 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EGG04955.1 - 4.4e-28 98.1 0.1 5.8e-23 81.5 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase E1_DerP2_DerF2 PF02221.10 EGG04955.1 - 0.14 12.4 0.0 0.49 10.6 0.0 1.9 2 0 0 2 2 2 0 ML domain KH_1 PF00013.24 EGG04956.1 - 2.2e-05 24.0 0.5 5.3e-05 22.7 0.3 1.6 1 0 0 1 1 1 1 KH domain Rep_fac_C PF08542.6 EGG04957.1 - 2.2e-22 78.8 0.3 4.9e-22 77.7 0.1 1.7 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGG04957.1 - 3.3e-11 43.1 0.0 2.8e-08 33.5 0.1 2.6 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.24 EGG04957.1 - 6.2e-10 39.3 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGG04957.1 - 4.6e-07 29.8 0.0 1.3e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGG04957.1 - 6.7e-06 26.2 0.1 0.00046 20.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGG04957.1 - 1.6e-05 25.0 0.2 0.064 13.4 0.0 2.6 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EGG04957.1 - 1.6e-05 24.5 0.0 2.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 EGG04957.1 - 5.4e-05 22.0 0.0 0.041 12.5 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EGG04957.1 - 8.4e-05 21.7 0.0 0.00024 20.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EGG04957.1 - 0.00047 19.7 0.0 0.00087 18.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EGG04957.1 - 0.00069 19.1 0.1 0.3 10.4 0.0 2.8 1 1 1 3 3 3 1 AAA-like domain AAA_19 PF13245.1 EGG04957.1 - 0.0017 18.0 0.0 0.0038 16.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EGG04957.1 - 0.0029 16.8 0.0 0.036 13.2 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGG04957.1 - 0.012 15.3 0.0 0.036 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EGG04957.1 - 0.014 14.7 0.2 0.062 12.6 0.1 2.0 2 1 0 2 2 2 0 AAA domain DEAD PF00270.24 EGG04957.1 - 0.014 14.8 0.1 0.39 10.1 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase NTPase_1 PF03266.10 EGG04957.1 - 0.016 14.9 0.2 0.068 12.8 0.1 2.1 1 1 1 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 EGG04957.1 - 0.017 14.5 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArgK PF03308.11 EGG04957.1 - 0.021 13.6 0.1 0.091 11.5 0.0 2.0 1 1 1 2 2 2 0 ArgK protein AAA_28 PF13521.1 EGG04957.1 - 0.028 14.3 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EGG04957.1 - 0.057 12.9 0.0 0.092 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGG04957.1 - 0.074 13.3 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain MipZ PF09140.6 EGG04957.1 - 0.086 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ AAA_31 PF13614.1 EGG04957.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EGG04957.1 - 0.12 12.6 0.1 0.15 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain Cellulase PF00150.13 EGG04960.1 - 8.1e-18 64.5 0.6 1.2e-17 64.0 0.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3357 PF11837.3 EGG04960.1 - 0.027 14.3 0.2 0.053 13.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Tmem26 PF09772.4 EGG04960.1 - 0.064 12.4 0.3 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 26 eIF-6 PF01912.13 EGG04961.1 - 1.9e-81 271.8 0.3 2.7e-81 271.4 0.2 1.2 1 0 0 1 1 1 1 eIF-6 family KH_3 PF13014.1 EGG04962.1 - 8.4e-07 28.5 0.3 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_1 PF00013.24 EGG04962.1 - 1.2e-06 28.0 0.0 0.0018 17.8 0.0 2.3 2 0 0 2 2 2 2 KH domain E1-E2_ATPase PF00122.15 EGG04963.1 - 1.5e-59 200.8 2.8 1.5e-59 200.8 1.9 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGG04963.1 - 9.4e-45 152.3 8.8 9.4e-45 152.3 6.1 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGG04963.1 - 8.3e-25 88.4 0.0 7.2e-19 69.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGG04963.1 - 4e-16 58.7 0.2 8.4e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGG04963.1 - 1.4e-15 56.5 0.1 5e-15 54.7 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGG04963.1 - 1.2e-12 48.4 0.0 5.2e-12 46.3 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGG04963.1 - 0.016 14.8 0.3 0.055 13.0 0.1 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase BAR PF03114.13 EGG04964.1 - 7.9e-35 120.4 4.6 1e-34 120.0 3.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EGG04964.1 - 2.3e-14 52.6 0.2 4.1e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGG04964.1 - 9.2e-14 50.5 0.1 1.5e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGG04964.1 - 3.1e-11 42.5 0.1 5.5e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain CorA PF01544.13 EGG04964.1 - 3.5 6.5 7.3 7.3 5.5 0.0 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Fcf2 PF08698.6 EGG04966.1 - 1.4e-18 66.6 0.1 2.1e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing SynMuv_product PF06047.6 EGG04967.1 - 2e-27 94.9 3.3 6.6e-27 93.3 2.3 1.7 1 1 0 1 1 1 1 Ras-induced vulval development antagonist Coprogen_oxidas PF01218.13 EGG04969.1 - 7.7e-125 415.3 0.0 8.7e-125 415.1 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase UPF0203 PF05254.7 EGG04969.1 - 0.086 12.7 1.4 0.15 11.9 0.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) SBDS_C PF09377.5 EGG04972.1 - 1.9e-38 130.9 0.7 3.4e-38 130.1 0.5 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EGG04972.1 - 4.1e-31 106.6 0.4 7.2e-31 105.8 0.3 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Orbi_VP3 PF01700.11 EGG04973.1 - 0.16 9.3 0.0 0.23 8.8 0.0 1.1 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein Aldo_ket_red PF00248.16 EGG04974.1 - 5e-18 64.9 0.0 6.7e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GYF PF02213.11 EGG04976.1 - 0.0011 18.4 1.0 0.0019 17.7 0.7 1.5 1 1 0 1 1 1 1 GYF domain Chitin_synth_2 PF03142.10 EGG04980.1 - 0.023 13.1 0.0 0.025 13.0 0.0 1.0 1 0 0 1 1 1 0 Chitin synthase PAS_8 PF13188.1 EGG04980.1 - 0.055 13.3 0.0 0.066 13.0 0.0 1.1 1 0 0 1 1 1 0 PAS domain Cupin_4 PF08007.7 EGG04980.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Cupin superfamily protein SynMuv_product PF06047.6 EGG04981.1 - 2.5e-46 155.7 3.2 2.5e-46 155.7 2.2 2.2 2 1 1 3 3 3 1 Ras-induced vulval development antagonist NTF2 PF02136.15 EGG04983.1 - 0.049 14.0 0.1 0.14 12.5 0.0 1.7 1 1 1 2 2 2 0 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.1 EGG04985.1 - 0.032 14.1 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain CBS PF00571.23 EGG04986.1 - 2.4e-30 104.0 3.6 6.6e-11 41.8 0.1 4.2 4 0 0 4 4 4 4 CBS domain F-box PF00646.28 EGG04987.1 - 0.014 15.0 0.4 3 7.5 0.0 3.2 2 0 0 2 2 2 0 F-box domain F-box-like_2 PF13013.1 EGG04987.1 - 0.031 14.0 1.1 0.078 12.7 0.1 2.1 2 0 0 2 2 2 0 F-box-like domain LRR_4 PF12799.2 EGG04987.1 - 3 7.5 15.2 1.3 8.7 0.1 5.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) zf-BED PF02892.10 EGG04989.1 - 0.0012 18.5 3.0 0.026 14.2 2.1 2.3 1 1 0 1 1 1 1 BED zinc finger zf-primase PF09329.6 EGG04989.1 - 0.027 14.0 0.6 0.046 13.3 0.4 1.4 1 0 0 1 1 1 0 Primase zinc finger Chon_Sulph_att PF06566.6 EGG04990.1 - 8.8 5.8 12.6 1.1 8.7 5.6 1.8 2 0 0 2 2 2 0 Chondroitin sulphate attachment domain LEA_1 PF03760.10 EGG04993.1 - 0.04 14.0 2.9 0.095 12.8 2.0 1.6 1 0 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 Med2 PF11214.3 EGG04993.1 - 4.2 7.4 9.2 2.5 8.1 3.5 2.5 3 0 0 3 3 3 0 Mediator complex subunit 2 WH1 PF00568.18 EGG04994.1 - 5.1e-11 42.2 0.0 8.9e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 EGG04994.1 - 3.2e-08 33.8 0.0 1.2e-07 31.9 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.15 EGG04994.1 - 0.0042 16.6 0.1 0.0097 15.4 0.1 1.7 1 0 0 1 1 1 1 WH2 motif DUF2633 PF11119.3 EGG04996.1 - 0.014 15.0 4.7 1.1 8.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) DctQ PF04290.7 EGG04996.1 - 5.5 6.7 15.0 1.2 8.8 0.8 3.4 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF1883 PF08980.5 EGG04997.1 - 0.0018 17.7 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1883) Oxysterol_BP PF01237.13 EGG04998.1 - 1e-91 307.0 0.0 1.3e-91 306.7 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Nitr_red_assoc PF09655.5 EGG04998.1 - 0.092 13.0 0.8 1.9 8.7 0.7 2.2 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF3595 PF12166.3 EGG04998.1 - 0.19 10.4 0.1 0.28 9.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) SCO1-SenC PF02630.9 EGG05003.1 - 3.8e-59 199.2 0.6 4.6e-59 198.9 0.4 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 EGG05003.1 - 2.8e-05 24.1 0.1 5.8e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EGG05003.1 - 0.033 13.8 0.0 0.056 13.1 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family zf-4CXXC_R1 PF10497.4 EGG05004.1 - 0.00043 20.3 13.2 0.0012 18.9 9.2 1.7 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Dicty_REP PF05086.7 EGG05005.1 - 5.7 4.5 8.0 7.1 4.2 5.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ras PF00071.17 EGG05006.1 - 2.1e-65 219.0 0.1 3.8e-65 218.2 0.1 1.4 1 1 1 2 2 2 1 Ras family Miro PF08477.8 EGG05006.1 - 8.7e-20 71.4 0.0 1.7e-19 70.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGG05006.1 - 7.9e-14 51.2 0.0 9.9e-14 50.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGG05006.1 - 5.7e-07 29.1 0.1 1.7e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGG05006.1 - 2.3e-06 26.9 0.0 2.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGG05006.1 - 1e-05 25.4 0.1 0.00038 20.3 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGG05006.1 - 0.0053 16.0 0.0 0.46 9.7 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.5 EGG05006.1 - 0.011 14.9 0.0 0.028 13.6 0.0 1.5 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EGG05006.1 - 0.025 13.7 0.0 0.047 12.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGG05006.1 - 0.03 14.4 0.0 0.051 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGG05006.1 - 0.032 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EGG05006.1 - 0.036 13.5 0.0 0.096 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 EGG05006.1 - 0.037 14.2 0.0 0.34 11.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 EGG05006.1 - 0.062 11.9 1.1 4.1 6.0 0.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit Septin PF00735.13 EGG05006.1 - 0.072 12.0 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Septin MCM PF00493.18 EGG05006.1 - 0.1 11.3 0.0 0.29 9.8 0.0 1.6 2 0 0 2 2 2 0 MCM2/3/5 family Cullin PF00888.17 EGG05009.1 - 2e-104 350.2 8.1 2.6e-104 349.8 5.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGG05009.1 - 2.3e-23 81.7 1.8 2.3e-23 81.7 1.2 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain SF3a60_bindingd PF12108.3 EGG05009.1 - 0.49 9.9 4.0 0.24 10.9 0.1 2.3 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain WAC_Acf1_DNA_bd PF10537.4 EGG05009.1 - 0.69 10.1 9.0 0.83 9.8 0.3 3.2 4 0 0 4 4 4 0 ATP-utilising chromatin assembly and remodelling N-terminal RabGAP-TBC PF00566.13 EGG05010.1 - 1.7e-48 164.9 0.2 1.7e-48 164.9 0.1 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3166 PF11365.3 EGG05010.1 - 0.0044 17.4 0.7 0.014 15.7 0.5 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3166) Glyco_hydro_2_N PF02837.13 EGG05017.1 - 0.0001 21.9 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4328 PF14219.1 EGG05017.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF848 PF05852.6 EGG05018.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) PQ-loop PF04193.9 EGG05019.1 - 6.2e-13 48.0 2.9 9.2e-13 47.5 2.0 1.3 1 0 0 1 1 1 1 PQ loop repeat eIF-5a PF01287.15 EGG05020.1 - 0.024 14.5 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold SKI PF01202.17 EGG05021.1 - 0.19 11.5 0.9 0.22 11.3 0.6 1.2 1 0 0 1 1 1 0 Shikimate kinase FAM176 PF14851.1 EGG05021.1 - 0.34 10.6 2.7 0.37 10.4 1.9 1.1 1 0 0 1 1 1 0 FAM176 family Trypan_glycop_C PF10659.4 EGG05021.1 - 3 8.1 8.8 3.7 7.8 6.1 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain YqfQ PF14181.1 EGG05021.1 - 3.6 7.6 10.3 3.9 7.4 7.1 1.1 1 0 0 1 1 1 0 YqfQ-like protein Spore_YhcN_YlaJ PF09580.5 EGG05021.1 - 5.6 7.0 12.1 5.9 6.9 8.4 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Otopetrin PF03189.8 EGG05021.1 - 9.7 5.0 6.4 10 5.0 4.4 1.0 1 0 0 1 1 1 0 Otopetrin Nucleo_P87 PF07267.6 EGG05023.1 - 2.9 6.4 5.5 3.7 6.1 3.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 THF_DHG_CYH_C PF02882.14 EGG05024.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GCM PF03615.10 EGG05025.1 - 0.0074 15.8 0.5 0.016 14.7 0.3 1.5 1 0 0 1 1 1 1 GCM motif protein Nop14 PF04147.7 EGG05025.1 - 1.3 6.8 10.1 1.6 6.5 7.0 1.0 1 0 0 1 1 1 0 Nop14-like family Use1 PF09753.4 EGG05026.1 - 0.57 9.5 5.6 0.71 9.2 3.9 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 TEX15 PF15326.1 EGG05026.1 - 2.1 7.9 4.3 2.7 7.5 3.0 1.2 1 0 0 1 1 1 0 Testis expressed sequence 15 Pox_Ag35 PF03286.9 EGG05028.1 - 0.17 11.4 6.0 0.26 10.7 4.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Peptidase_A6 PF01829.11 EGG05029.1 - 0.086 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase A6 family Activator_LAG-3 PF11498.3 EGG05030.1 - 0.054 12.2 0.0 0.071 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CDP-OH_P_transf PF01066.16 EGG05032.1 - 1.2e-09 38.3 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF2691 PF10903.3 EGG05032.1 - 0.097 12.4 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2691) ArsA_ATPase PF02374.10 EGG05033.1 - 1.1e-111 372.6 0.1 1.3e-111 372.4 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EGG05033.1 - 5.6e-16 58.5 0.0 7.9e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGG05033.1 - 1.7e-08 34.5 0.0 6.1e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EGG05033.1 - 2.4e-05 23.6 0.0 7.7e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EGG05033.1 - 0.00054 19.4 0.1 0.0066 15.9 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EGG05033.1 - 0.0025 17.2 0.1 0.015 14.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain YhjQ PF06564.7 EGG05033.1 - 0.012 15.0 0.0 0.032 13.5 0.0 1.7 3 0 0 3 3 3 0 YhjQ protein MipZ PF09140.6 EGG05033.1 - 0.019 14.0 0.0 0.055 12.5 0.0 1.7 2 0 0 2 2 2 0 ATPase MipZ AAA_19 PF13245.1 EGG05033.1 - 0.019 14.6 0.1 0.071 12.8 0.1 1.8 1 1 0 1 1 1 0 Part of AAA domain VirC1 PF07015.6 EGG05033.1 - 0.035 13.1 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein PhoH PF02562.11 EGG05033.1 - 0.087 12.0 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 EGG05033.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.12 EGG05033.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGG05033.1 - 0.14 11.1 0.0 0.47 9.5 0.0 1.8 3 0 0 3 3 3 0 Zeta toxin DNA_primase_lrg PF04104.9 EGG05036.1 - 1.5e-77 260.3 0.0 2.3e-77 259.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit SoxE PF06525.6 EGG05037.1 - 0.0061 15.8 5.9 0.19 10.9 3.2 2.1 2 0 0 2 2 2 2 Sulfocyanin (SoxE) PspB PF06667.7 EGG05038.1 - 0.017 15.0 1.0 0.06 13.2 0.7 1.9 1 0 0 1 1 1 0 Phage shock protein B Phage_CP76 PF06892.6 EGG05040.1 - 0.022 14.0 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) cNMP_binding PF00027.24 EGG05042.1 - 9.5e-39 131.1 0.3 9.1e-19 67.0 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RtcB PF01139.12 EGG05042.1 - 0.046 12.7 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB Noc2 PF03715.8 EGG05047.1 - 4.1e-108 360.7 2.7 1.5e-106 355.6 0.4 2.8 3 0 0 3 3 3 2 Noc2p family RXT2_N PF08595.6 EGG05047.1 - 3.8 7.3 12.7 4.2 7.1 3.0 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal WD40 PF00400.27 EGG05048.1 - 2e-07 30.5 0.2 0.41 10.6 0.0 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat MFS_1 PF07690.11 EGG05049.1 - 9.6e-41 139.6 53.7 2.5e-40 138.3 35.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG05049.1 - 8.4e-13 47.6 34.6 1.1e-10 40.6 11.4 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter SpoIISA_toxin PF14171.1 EGG05049.1 - 0.75 9.0 5.1 1.3 8.2 3.5 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system MFS_1 PF07690.11 EGG05050.1 - 2.6e-42 144.8 40.4 4.3e-42 144.1 28.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG05050.1 - 2.9e-10 39.3 32.6 9.4e-08 31.0 10.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter CUE PF02845.11 EGG05051.1 - 2.1e-05 23.9 0.0 0.00042 19.7 0.0 2.3 2 0 0 2 2 2 1 CUE domain GPI-anchored PF10342.4 EGG05053.1 - 0.0037 17.7 0.0 0.02 15.3 0.0 2.0 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FMN_red PF03358.10 EGG05054.1 - 3.7e-09 36.2 0.0 5.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EGG05054.1 - 0.00097 18.6 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 EGG05054.1 - 0.0026 17.7 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_4 PF12682.2 EGG05054.1 - 0.048 13.0 0.0 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Flavodoxin His_Phos_1 PF00300.17 EGG05055.1 - 1.1e-42 145.7 0.0 1.4e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Poxvirus_B22R_N PF13169.1 EGG05057.1 - 0.1 12.7 0.1 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 Poxvirus B22R protein N-terminal GET2 PF08690.5 EGG05057.1 - 0.11 11.6 0.1 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 HTH_21 PF13276.1 EGG05058.1 - 0.026 14.5 0.1 0.077 13.0 0.1 1.8 1 0 0 1 1 1 0 HTH-like domain FAR1 PF03101.10 EGG05059.1 - 0.0045 17.4 0.1 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EGG05059.1 - 0.14 12.3 0.5 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 Transcription factor AFT UvrD_C_2 PF13538.1 EGG05062.1 - 2.7e-05 24.2 0.0 3.9e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EGG05062.1 - 0.00089 17.1 0.0 0.001 16.9 0.0 1.0 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EGG05062.1 - 0.034 13.6 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SWIM PF04434.12 EGG05064.1 - 8.1e-08 31.5 8.2 0.0017 17.7 1.4 2.6 3 0 0 3 3 3 2 SWIM zinc finger DUF1924 PF09086.6 EGG05064.1 - 0.06 13.3 0.1 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) LRR_6 PF13516.1 EGG05072.1 - 1.5e-14 52.3 23.1 0.045 13.8 0.1 9.9 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.2 EGG05072.1 - 9.3e-07 28.3 28.8 5.3e-05 22.7 0.5 7.1 6 2 3 9 9 9 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGG05072.1 - 0.0042 16.9 18.2 40 4.8 0.0 9.2 9 2 1 10 10 10 0 Leucine Rich Repeat LRR_8 PF13855.1 EGG05072.1 - 0.0069 16.1 23.1 0.4 10.4 0.5 6.4 4 3 1 5 5 5 3 Leucine rich repeat Phage_head_fibr PF11133.3 EGG05072.1 - 0.032 13.4 0.2 0.057 12.6 0.1 1.3 1 0 0 1 1 1 0 Head fiber protein RdRP PF05183.7 EGG05073.1 - 2.2e-155 518.6 0.0 3.1e-155 518.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Hexokinase_2 PF03727.11 EGG05074.1 - 6.6e-84 280.9 0.0 8.9e-84 280.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EGG05074.1 - 8e-68 227.8 0.0 1.7e-67 226.7 0.0 1.5 2 0 0 2 2 2 1 Hexokinase DUF2779 PF11074.3 EGG05074.1 - 0.038 14.0 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) Lin-8 PF03353.10 EGG05074.1 - 0.12 11.6 0.6 0.17 11.0 0.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RTTN_N PF14726.1 EGG05075.1 - 0.09 13.3 1.4 1.9 9.0 0.3 2.4 1 1 1 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning NUC130_3NT PF08158.7 EGG05075.1 - 0.1 12.8 0.2 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 NUC130/3NT domain Luciferase_3H PF10284.4 EGG05075.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Luciferase helical bundle domain AhpC-TSA PF00578.16 EGG05077.1 - 5.1e-21 74.6 0.1 9.4e-21 73.7 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EGG05077.1 - 8.6e-12 44.8 0.0 1.4e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EGG05077.1 - 0.0041 17.0 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Presenilin PF01080.12 EGG05077.1 - 2.9 6.6 9.3 3.9 6.1 6.5 1.1 1 0 0 1 1 1 0 Presenilin Corona_nucleoca PF00937.13 EGG05077.1 - 3.7 6.3 13.9 5.9 5.7 9.6 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PIN_4 PF13638.1 EGG05079.1 - 2.8e-22 79.2 0.4 8.5e-22 77.6 0.3 1.9 1 0 0 1 1 1 1 PIN domain ATG13 PF10033.4 EGG05081.1 - 8e-35 120.3 0.0 1.1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 Dus PF01207.12 EGG05082.1 - 1.2e-53 181.9 0.0 2e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) IF-2B PF01008.12 EGG05083.1 - 2.4e-49 167.8 0.0 2.9e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 EGG05083.1 - 0.088 12.4 0.5 0.25 10.9 0.4 1.7 1 1 0 1 1 1 0 DeoR C terminal sensor domain Pyrophosphatase PF00719.14 EGG05084.1 - 7.8e-54 181.3 0.1 1e-53 180.9 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Ribosomal_S8 PF00410.14 EGG05087.1 - 2.8e-25 88.6 0.0 3.7e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 WD40 PF00400.27 EGG05088.1 - 1.6e-61 202.0 13.9 7.2e-15 54.2 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EGG05088.1 - 1.4e-28 99.7 0.0 2.8e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 EGG05088.1 - 3.5e-05 23.5 0.0 0.00049 19.8 0.0 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EGG05088.1 - 0.0058 15.4 0.4 0.063 12.0 0.3 2.4 1 1 0 1 1 1 1 Nup133 N terminal like LisH PF08513.6 EGG05088.1 - 0.016 14.9 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 LisH zf-C3HC4_3 PF13920.1 EGG05089.1 - 3.7e-09 36.0 2.7 5.8e-09 35.4 1.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGG05089.1 - 4.2e-09 36.0 3.2 6.3e-09 35.5 2.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGG05089.1 - 1.2e-08 34.8 1.8 2.6e-08 33.7 1.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG05089.1 - 3e-08 33.2 3.0 5.1e-08 32.5 2.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGG05089.1 - 1.7e-07 30.7 0.3 3.3e-07 29.8 0.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PRCC PF10253.4 EGG05089.1 - 0.012 16.2 4.0 0.012 16.2 2.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting zf-RING_UBOX PF13445.1 EGG05089.1 - 0.029 14.1 4.4 0.084 12.6 1.4 2.5 1 1 1 2 2 2 0 RING-type zinc-finger Trypan_PARP PF05887.6 EGG05089.1 - 0.07 12.9 12.2 0.13 12.1 8.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-C3HC4_4 PF15227.1 EGG05089.1 - 0.085 12.7 5.6 0.46 10.3 1.7 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.9 EGG05089.1 - 0.093 12.2 0.2 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif Prok-RING_4 PF14447.1 EGG05089.1 - 0.15 11.6 4.4 0.64 9.6 0.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Pex14_N PF04695.8 EGG05089.1 - 0.2 11.7 4.1 0.23 11.4 2.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pox_P35 PF03213.9 EGG05089.1 - 0.57 9.1 1.8 0.66 8.9 1.2 1.1 1 0 0 1 1 1 0 Poxvirus P35 protein zf-RING_4 PF14570.1 EGG05089.1 - 0.88 9.2 4.0 3.7 7.2 2.8 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EGG05089.1 - 1.1 9.0 4.2 2.6 7.9 0.9 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF1179 PF06678.6 EGG05089.1 - 1.8 8.9 5.5 1.1 9.6 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Bravo_FIGEY PF13882.1 EGG05089.1 - 5.5 7.9 8.6 8.6 7.3 5.9 1.3 1 0 0 1 1 1 0 Bravo-like intracellular region Tmemb_55A PF09788.4 EGG05089.1 - 5.6 6.0 10.2 7.8 5.5 5.5 1.9 1 1 1 2 2 2 0 Transmembrane protein 55A Neisseria_TspB PF05616.8 EGG05089.1 - 8.6 4.5 10.6 12 4.0 7.3 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF4551 PF15087.1 EGG05089.1 - 8.8 4.5 6.1 9.9 4.3 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PIG-L PF02585.12 EGG05093.1 - 4.7e-17 62.7 0.0 8.8e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ApbA_C PF08546.6 EGG05094.1 - 3.7e-21 75.4 0.0 5.5e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EGG05094.1 - 3e-20 72.1 0.0 1e-19 70.4 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA PP2C PF00481.16 EGG05094.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C NSP2-B_epitope PF14757.1 EGG05095.1 - 0.15 11.5 4.7 0.23 10.9 3.3 1.2 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Ank_2 PF12796.2 EGG05096.1 - 0.00072 19.8 0.0 0.0022 18.2 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGG05096.1 - 0.001 19.2 0.0 0.71 10.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGG05096.1 - 0.0018 18.7 0.0 0.064 13.8 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EGG05096.1 - 0.013 15.2 0.5 0.33 10.8 0.0 3.0 3 1 0 3 3 3 0 Ankyrin repeat Peptidase_S8 PF00082.17 EGG05098.1 - 3.6e-42 144.4 3.4 6.6e-42 143.6 2.3 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGG05098.1 - 2.1e-07 31.4 0.7 4.4e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 zf-RING_2 PF13639.1 EGG05099.1 - 1.2e-06 28.2 7.5 1.2e-06 28.2 5.2 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGG05099.1 - 0.00049 19.7 5.8 0.00052 19.6 3.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG05099.1 - 0.0029 17.2 7.8 0.006 16.2 5.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Endonuclease_7 PF02945.10 EGG05099.1 - 0.079 12.6 1.9 0.16 11.7 1.3 1.4 1 0 0 1 1 1 0 Recombination endonuclease VII Prok-RING_1 PF14446.1 EGG05099.1 - 0.094 12.4 4.0 0.24 11.1 2.8 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 EGG05099.1 - 0.23 11.5 7.1 0.58 10.2 4.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EGG05099.1 - 5.5 7.0 6.9 38 4.3 1.8 2.5 2 0 0 2 2 2 0 zinc-finger zf-RING_2 PF13639.1 EGG05101.1 - 3.5e-06 26.7 1.5 3.5e-06 26.7 1.0 2.4 3 0 0 3 3 3 1 Ring finger domain DUF4202 PF13875.1 EGG05101.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) ATP_bind_3 PF01171.15 EGG05102.1 - 1.7e-17 63.5 0.0 4.7e-17 62.0 0.0 1.7 2 0 0 2 2 2 1 PP-loop family tRNA_Me_trans PF03054.11 EGG05102.1 - 0.0022 16.6 0.0 0.0031 16.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 EGG05102.1 - 0.043 13.3 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase PAPS_reduct PF01507.14 EGG05102.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.9 EGG05102.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) RNB PF00773.14 EGG05103.1 - 4.4e-52 177.3 0.0 1e-51 176.2 0.0 1.6 2 0 0 2 2 2 1 RNB domain ATP_transf PF09830.4 EGG05107.1 - 3.5e-18 65.1 0.0 7.1e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase PPR_2 PF13041.1 EGG05108.1 - 0.00051 19.9 0.2 10 6.2 0.0 4.7 4 0 0 4 4 4 1 PPR repeat family TPR_8 PF13181.1 EGG05108.1 - 0.025 14.3 0.2 15 5.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 EGG05108.1 - 0.11 12.4 4.2 34 4.7 0.1 5.3 6 0 0 6 6 6 0 PPR repeat TPR_1 PF00515.23 EGG05108.1 - 0.12 11.9 0.9 35 4.2 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGG05108.1 - 0.25 11.3 1.1 67 3.7 0.1 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.13 EGG05109.1 - 0.00046 20.0 2.2 0.0011 18.7 1.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EGG05113.1 - 2.9e-57 193.7 0.0 3.5e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG05113.1 - 4.8e-25 88.1 0.0 8.2e-25 87.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG05113.1 - 5.5e-06 25.5 0.0 8.5e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGG05113.1 - 0.0083 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGG05113.1 - 0.036 13.7 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myosin_tail_1 PF01576.14 EGG05114.1 - 0.0071 14.1 0.3 0.0097 13.6 0.2 1.1 1 0 0 1 1 1 1 Myosin tail Bap31 PF05529.7 EGG05114.1 - 0.023 14.1 0.8 0.043 13.2 0.5 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like V_ATPase_I PF01496.14 EGG05114.1 - 0.024 12.5 0.0 0.031 12.1 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.13 EGG05114.1 - 0.091 12.4 0.0 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Glyco_hydro_43 PF04616.9 EGG05115.1 - 1.8e-36 125.6 2.2 3.5e-36 124.7 1.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 zf-RING_2 PF13639.1 EGG05117.1 - 2.1e-08 33.8 7.6 4.4e-08 32.8 5.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 EGG05117.1 - 0.017 14.9 5.8 0.071 12.9 4.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGG05117.1 - 0.017 15.2 4.3 0.043 13.9 3.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGG05117.1 - 0.029 14.0 5.5 0.057 13.0 3.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG05117.1 - 0.06 13.0 6.0 0.14 11.9 4.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain RRN7 PF11781.3 EGG05117.1 - 0.13 11.7 2.6 2.1 7.9 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C3HC4_2 PF13923.1 EGG05117.1 - 0.35 10.9 8.1 0.78 9.8 5.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RecR PF02132.10 EGG05117.1 - 0.6 9.5 6.2 0.29 10.6 0.5 2.6 2 0 0 2 2 2 0 RecR protein zf-C3HC4 PF00097.20 EGG05117.1 - 4.1 7.1 7.1 10 5.8 4.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Aminotran_1_2 PF00155.16 EGG05118.1 - 2.5e-26 92.4 0.0 3.1e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II AA_permease PF00324.16 EGG05119.1 - 3e-124 414.9 37.5 3.8e-124 414.6 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGG05119.1 - 9.1e-35 120.0 40.6 1.2e-34 119.6 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4366 PF14283.1 EGG05119.1 - 0.074 12.4 0.3 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) RNA_pol_Rpb4 PF03874.11 EGG05120.1 - 9.7e-17 61.0 0.0 1.2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1059 PF06348.6 EGG05120.1 - 0.0048 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) UNC-50 PF05216.8 EGG05121.1 - 1.1e-70 237.4 19.8 2.2e-70 236.4 13.7 1.4 1 1 0 1 1 1 1 UNC-50 family Scramblase PF03803.10 EGG05122.1 - 1e-57 194.7 0.0 1.3e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Scramblase F-box PF00646.28 EGG05123.1 - 0.0088 15.6 0.1 2.4 7.8 0.0 2.6 2 0 0 2 2 2 2 F-box domain LRR_4 PF12799.2 EGG05123.1 - 0.34 10.5 2.4 26 4.5 2.4 3.0 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) BIR PF00653.16 EGG05124.1 - 3.7e-29 100.9 3.9 6.7e-15 55.2 0.4 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Ribosomal_L44 PF00935.14 EGG05127.1 - 1.1e-35 121.4 10.7 1.7e-35 120.8 7.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 APS_kinase PF01583.15 EGG05132.1 - 5.6e-66 221.0 0.0 6.7e-66 220.7 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EGG05132.1 - 1.8e-07 31.1 0.0 2.4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG05132.1 - 1.9e-07 31.4 0.2 3.5e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG05132.1 - 6.4e-07 30.2 0.0 1e-06 29.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGG05132.1 - 5.6e-05 22.4 0.0 7.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 SRP54 PF00448.17 EGG05132.1 - 0.0005 19.5 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 EGG05132.1 - 0.0018 17.6 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EGG05132.1 - 0.0022 17.7 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGG05132.1 - 0.0024 17.8 0.1 0.0043 17.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain PRK PF00485.13 EGG05132.1 - 0.0028 17.2 0.0 0.0057 16.2 0.0 1.5 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 EGG05132.1 - 0.0034 16.8 0.0 0.0055 16.1 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 EGG05132.1 - 0.0036 16.8 0.1 0.006 16.0 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EGG05132.1 - 0.0095 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin PEPCK_ATP PF01293.15 EGG05132.1 - 0.013 14.0 0.1 0.016 13.7 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase RNA_helicase PF00910.17 EGG05132.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EGG05132.1 - 0.025 14.8 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.12 EGG05132.1 - 0.056 13.2 0.9 2.9 7.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 ArgK PF03308.11 EGG05132.1 - 0.062 12.0 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Clusterin PF01093.12 EGG05132.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Clusterin DUF258 PF03193.11 EGG05132.1 - 0.15 11.1 0.1 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PH PF00169.24 EGG05133.1 - 6.9e-33 112.9 4.6 6.5e-19 68.0 0.6 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EGG05133.1 - 1.1e-19 70.7 12.5 9.4e-09 35.5 0.2 3.5 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 EGG05133.1 - 2e-12 46.9 11.1 1e-07 31.7 1.5 3.2 3 0 0 3 3 3 3 PH domain PH_8 PF15409.1 EGG05133.1 - 1e-07 31.9 9.7 3.2e-06 27.1 1.2 3.1 2 1 1 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.1 EGG05133.1 - 2.3e-06 27.7 4.4 0.022 14.8 0.0 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH_4 PF15404.1 EGG05133.1 - 0.0003 20.3 3.9 0.52 9.8 0.1 3.5 2 1 1 3 3 3 2 Pleckstrin homology domain Mcp5_PH PF12814.2 EGG05133.1 - 0.00079 19.3 2.2 0.37 10.7 0.1 2.6 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_6 PF15406.1 EGG05133.1 - 0.029 14.4 0.1 0.28 11.2 0.0 2.5 3 0 0 3 3 3 0 Pleckstrin homology domain Sec3-PIP2_bind PF15277.1 EGG05133.1 - 0.043 13.6 0.2 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH His_binding PF02098.11 EGG05133.1 - 0.1 12.4 3.5 1.5 8.6 0.2 2.9 3 0 0 3 3 3 0 Tick histamine binding protein Mito_carr PF00153.22 EGG05134.1 - 5.3e-48 160.6 0.0 3.2e-23 81.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L14e PF01929.12 EGG05135.1 - 6.2e-27 93.7 0.9 8.7e-27 93.2 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 His_Phos_1 PF00300.17 EGG05141.1 - 1.5e-13 51.1 0.0 2.3e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DER1 PF04511.10 EGG05142.1 - 1.6e-30 106.0 0.0 2.1e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Der1-like family BRO1 PF03097.13 EGG05143.1 - 4.4e-12 45.4 0.0 7.6e-12 44.6 0.0 1.4 1 1 0 1 1 1 1 BRO1-like domain SARA PF11409.3 EGG05144.1 - 0.46 10.4 5.5 1.9 8.4 3.8 2.1 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) bZIP_2 PF07716.10 EGG05145.1 - 1.7e-06 27.7 5.0 1.7e-06 27.7 3.4 2.6 2 1 1 3 3 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EGG05145.1 - 4.5e-06 26.5 12.7 3.4e-05 23.6 7.0 2.8 2 2 0 2 2 2 1 bZIP transcription factor Phage_GP20 PF06810.6 EGG05145.1 - 0.00071 19.0 3.4 0.0015 17.9 2.3 1.5 1 0 0 1 1 1 1 Phage minor structural protein GP20 DUF972 PF06156.8 EGG05145.1 - 0.0012 19.1 0.5 0.0012 19.1 0.3 2.2 2 1 1 3 3 2 1 Protein of unknown function (DUF972) HrpB7 PF09486.5 EGG05145.1 - 0.0048 16.8 0.2 0.0089 15.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) MscS_porin PF12795.2 EGG05145.1 - 0.011 15.0 3.9 0.011 15.0 2.7 1.9 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ADIP PF11559.3 EGG05145.1 - 0.019 14.8 1.7 0.019 14.8 1.2 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CASP_C PF08172.7 EGG05145.1 - 0.019 13.9 1.9 0.039 12.9 1.3 1.5 1 0 0 1 1 1 0 CASP C terminal TPD52 PF04201.10 EGG05145.1 - 0.038 13.7 1.1 0.098 12.3 0.7 1.7 1 0 0 1 1 1 0 Tumour protein D52 family DivIC PF04977.10 EGG05145.1 - 0.042 13.3 0.7 0.042 13.3 0.5 1.8 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 EGG05145.1 - 0.044 14.1 1.7 0.14 12.5 0.5 2.4 2 0 0 2 2 2 0 SlyX bZIP_Maf PF03131.12 EGG05145.1 - 0.079 13.2 4.1 0.18 12.1 2.9 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor HALZ PF02183.13 EGG05145.1 - 0.14 11.9 0.9 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper RNase_HII PF01351.13 EGG05145.1 - 0.16 11.5 2.4 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease HII Spc7 PF08317.6 EGG05145.1 - 0.17 10.4 8.1 0.049 12.2 3.6 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 EGG05145.1 - 0.53 10.1 8.0 0.089 12.6 2.7 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 EGG05145.1 - 0.61 9.8 10.3 0.083 12.7 3.8 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 EGG05145.1 - 0.62 9.8 3.9 1.4 8.7 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PGBA_C PF15437.1 EGG05145.1 - 0.86 9.7 4.8 1.1 9.4 2.6 1.7 2 0 0 2 2 1 0 Plasminogen-binding protein pgbA C-terminal FlaC_arch PF05377.6 EGG05145.1 - 0.89 9.4 3.5 1.7 8.6 0.4 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EGG05145.1 - 2.5 7.6 7.9 0.46 10.0 2.9 1.6 2 0 0 2 2 2 0 IncA protein AAA_13 PF13166.1 EGG05145.1 - 6.9 4.9 10.5 0.15 10.4 2.6 1.5 2 0 0 2 2 2 0 AAA domain DivIVA PF05103.8 EGG05145.1 - 9.9 6.2 9.8 0.94 9.5 0.1 3.0 2 2 1 3 3 3 0 DivIVA protein zf-PARP PF00645.13 EGG05148.1 - 3.4e-19 68.8 3.3 4.5e-17 62.0 0.1 2.4 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Exo70 PF03081.10 EGG05149.1 - 3.2e-51 174.2 0.0 9.2e-51 172.7 0.0 1.7 2 0 0 2 2 2 1 Exo70 exocyst complex subunit CorA PF01544.13 EGG05149.1 - 0.0019 17.3 0.5 0.19 10.7 0.0 2.5 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein COG2 PF06148.6 EGG05149.1 - 0.08 12.8 0.0 0.32 10.8 0.0 2.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec3_C PF09763.4 EGG05149.1 - 0.31 9.1 3.0 0.49 8.4 0.1 2.4 3 0 0 3 3 3 0 Exocyst complex component Sec3 Baculo_PEP_C PF04513.7 EGG05149.1 - 0.77 9.5 4.8 1.8 8.3 2.6 2.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HUN PF08729.5 EGG05150.1 - 7.3e-11 41.7 0.0 1.8e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 EGG05150.1 - 2.2e-07 30.7 3.4 3.6e-06 26.8 2.3 2.4 1 1 0 1 1 1 1 Ubinuclein conserved middle domain DUF702 PF05142.7 EGG05151.1 - 0.02 15.0 4.5 0.041 14.0 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Inh PF02974.9 EGG05153.1 - 0.031 13.8 0.0 0.095 12.2 0.0 1.7 2 0 0 2 2 2 0 Protease inhibitor Inh RNA_pol_Rpb2_45 PF10385.4 EGG05155.1 - 0.059 13.1 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase beta subunit external 1 domain SUZ PF12752.2 EGG05158.1 - 2.8e-08 34.1 0.0 2.8e-08 34.1 0.0 3.0 4 0 0 4 4 4 1 SUZ domain Oest_recep PF02159.10 EGG05158.1 - 0.36 10.9 9.5 0.019 15.0 3.0 1.5 2 0 0 2 2 2 0 Oestrogen receptor USP7_ICP0_bdg PF12436.3 EGG05160.1 - 0.0097 15.1 0.1 0.018 14.3 0.0 1.3 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 LSM PF01423.17 EGG05162.1 - 2.8e-12 46.0 0.2 3.8e-12 45.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGG05162.1 - 0.00076 19.3 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Fungal_trans PF04082.13 EGG05163.1 - 0.0096 14.8 0.3 0.022 13.6 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGG05163.1 - 0.012 15.4 4.4 0.034 14.0 3.0 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGAP PF00620.22 EGG05165.1 - 6.9e-31 106.9 0.0 1.6e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LRR_4 PF12799.2 EGG05166.1 - 0.067 12.8 5.5 1.8 8.2 0.1 4.5 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) RGS PF00615.14 EGG05168.1 - 5.9e-05 23.1 0.0 6e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3463 PF11946.3 EGG05170.1 - 0.025 14.1 0.6 0.046 13.3 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) DUF2100 PF09873.4 EGG05171.1 - 0.023 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) DnaJ PF00226.26 EGG05172.1 - 4e-14 52.0 0.1 1.1e-13 50.7 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain Selenoprotein_S PF06936.6 EGG05172.1 - 3.7 7.0 8.5 6.4 6.2 5.9 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) WD40 PF00400.27 EGG05173.1 - 1.2e-06 28.1 0.8 0.001 18.8 0.0 2.8 3 1 0 3 3 3 2 WD domain, G-beta repeat WD40 PF00400.27 EGG05174.1 - 4.9e-14 51.5 4.7 0.0034 17.2 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EGG05174.1 - 0.029 14.0 0.5 0.41 10.3 0.0 2.7 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A CBF_beta PF02312.12 EGG05174.1 - 0.038 13.6 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Core binding factor beta subunit AAA PF00004.24 EGG05175.1 - 4.6e-16 59.2 0.0 7.7e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGG05175.1 - 1.4e-13 51.2 0.1 6.9e-13 48.9 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGG05175.1 - 2e-08 34.4 0.0 1.4e-07 31.7 0.0 1.9 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 EGG05175.1 - 5.6e-06 26.1 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EGG05175.1 - 8.9e-05 22.2 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase Bac_DnaA PF00308.13 EGG05175.1 - 0.00016 21.4 0.1 0.0014 18.3 0.1 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein DUF2075 PF09848.4 EGG05175.1 - 0.00075 18.5 0.0 0.00096 18.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EGG05175.1 - 0.00094 18.8 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EGG05175.1 - 0.0043 16.6 0.0 0.0062 16.1 0.0 1.2 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EGG05175.1 - 0.01 15.8 0.0 1.2 9.2 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EGG05175.1 - 0.027 14.2 0.3 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 EGG05175.1 - 0.059 13.5 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_3 PF07726.6 EGG05175.1 - 0.068 12.7 0.0 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PPV_E1_C PF00519.12 EGG05175.1 - 0.068 11.7 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Arf PF00025.16 EGG05175.1 - 0.097 11.9 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Pyridoxal_deC PF00282.14 EGG05176.1 - 3.3e-58 196.9 0.0 4.8e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain CsbD PF05532.7 EGG05176.1 - 9.8e-14 50.7 13.3 2.2e-09 36.8 3.4 2.4 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.7 EGG05176.1 - 0.11 12.5 0.3 0.28 11.3 0.2 1.7 1 0 0 1 1 1 0 Heat shock protein 9/12 DUF4125 PF13526.1 EGG05176.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) MIP PF00230.15 EGG05177.1 - 3e-26 92.2 10.8 3.6e-26 92.0 7.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Pyridoxal_deC PF00282.14 EGG05178.1 - 1.9e-53 181.2 0.0 2.5e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF4125 PF13526.1 EGG05178.1 - 0.0082 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4125) Aminotran_5 PF00266.14 EGG05178.1 - 0.028 13.1 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGG05179.1 - 1.4e-37 129.4 0.0 1.7e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 EGG05179.1 - 0.0092 14.8 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III WD40 PF00400.27 EGG05180.1 - 0.0016 18.2 0.0 0.059 13.2 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat COG4 PF08318.7 EGG05181.1 - 0.11 11.1 0.2 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 COG4 transport protein Auxin_repressed PF05564.7 EGG05182.1 - 2.3 8.8 6.3 1.5 9.3 0.7 2.5 2 1 0 2 2 2 0 Dormancy/auxin associated protein SNF2_N PF00176.18 EGG05183.1 - 1.3e-44 152.2 0.5 1.4e-44 152.1 0.4 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGG05183.1 - 5.1e-08 32.5 0.0 6.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGG05183.1 - 0.0037 17.1 0.0 0.0062 16.3 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGG05184.1 - 2.2e-13 49.8 0.0 4.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Hamartin PF04388.7 EGG05185.1 - 1.5 7.3 7.8 2.9 6.4 5.4 1.4 1 0 0 1 1 1 0 Hamartin protein Endonuclease_NS PF01223.18 EGG05186.1 - 2.3e-52 177.6 0.1 6.7e-52 176.1 0.0 1.7 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease KH_1 PF00013.24 EGG05187.1 - 0.00037 20.0 0.0 0.001 18.6 0.0 1.8 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EGG05187.1 - 0.00056 19.4 0.1 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 KH domain Amidohydro_1 PF01979.15 EGG05188.1 - 1.2e-33 117.1 0.0 3.1e-33 115.8 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGG05188.1 - 2.3e-06 27.3 0.0 7.1e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGG05188.1 - 0.00098 18.4 0.0 0.54 9.4 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EGG05188.1 - 0.031 14.2 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase Pex14_N PF04695.8 EGG05189.1 - 0.25 11.3 2.2 0.39 10.7 1.5 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CTP_transf_1 PF01148.15 EGG05190.1 - 2.6e-65 220.6 23.4 3.4e-65 220.2 16.2 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family SHR3_chaperone PF08229.6 EGG05190.1 - 0.0066 15.4 0.8 0.019 13.9 0.6 1.7 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4235 PF14019.1 EGG05190.1 - 0.99 9.3 3.5 36 4.2 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4235) RRM_1 PF00076.17 EGG05191.1 - 4.6e-11 42.1 0.2 2.5e-05 23.8 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG05191.1 - 9.5e-11 41.5 0.1 1.8e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG05191.1 - 0.00031 20.5 0.1 0.012 15.4 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DMPK_coil PF08826.5 EGG05191.1 - 0.13 12.1 3.7 0.34 10.8 2.6 1.8 1 0 0 1 1 1 0 DMPK coiled coil domain like Vpu PF00558.14 EGG05191.1 - 0.29 10.6 2.4 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Vpu protein Peptidase_S49_N PF08496.5 EGG05191.1 - 0.71 9.6 13.9 0.12 12.2 2.5 2.9 3 0 0 3 3 3 0 Peptidase family S49 N-terminal DUF2711 PF10924.3 EGG05192.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) PX PF00787.19 EGG05194.1 - 6e-25 87.2 0.1 8.1e-25 86.8 0.1 1.2 1 0 0 1 1 1 1 PX domain Adeno_E1B_19K PF01691.11 EGG05194.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen CDC27 PF09507.5 EGG05195.1 - 7e-07 28.8 75.1 0.00025 20.3 51.1 3.6 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 ALS_ss_C PF10369.4 EGG05198.1 - 7.5e-18 64.0 0.0 7.9e-16 57.5 0.0 2.3 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.20 EGG05198.1 - 1.8e-12 46.4 0.2 5.5e-12 44.9 0.0 1.9 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.1 EGG05198.1 - 8.2e-09 35.1 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 ACT domain mRNA_cap_enzyme PF01331.14 EGG05200.1 - 0.039 13.6 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain Helitron_like_N PF14214.1 EGG05200.1 - 0.1 12.3 0.0 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus RED_N PF07808.8 EGG05201.1 - 1.1e-18 67.3 4.7 1.1e-18 67.3 3.2 2.1 2 0 0 2 2 2 1 RED-like protein N-terminal region Alpha_kinase PF02816.13 EGG05203.1 - 5.1e-05 23.0 1.1 5.1e-05 23.0 0.8 2.2 3 1 0 3 3 3 1 Alpha-kinase family zf-CCHC PF00098.18 EGG05204.1 - 0.00027 20.7 1.1 0.00054 19.7 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF3439 PF11921.3 EGG05208.1 - 0.046 13.4 0.5 0.084 12.6 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF963 PF06131.6 EGG05208.1 - 2.2 7.6 10.6 4.2 6.7 7.4 1.4 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) FAD_binding_4 PF01565.18 EGG05209.1 - 5.3e-27 94.0 2.4 8.3e-27 93.3 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGG05209.1 - 1.6e-14 53.4 1.1 2.9e-14 52.6 0.8 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EGG05209.1 - 0.0096 15.0 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding RhgB_N PF09284.5 EGG05211.1 - 0.02 14.2 0.1 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Rhamnogalacturonase B, N-terminal Transp_cyt_pur PF02133.10 EGG05212.1 - 0.087 11.3 0.1 0.15 10.5 0.1 1.3 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin Mis12 PF05859.7 EGG05214.1 - 2.9e-14 53.0 0.3 7e-14 51.8 0.1 1.7 1 1 1 2 2 2 1 Mis12 protein APG6 PF04111.7 EGG05214.1 - 0.092 11.7 0.3 0.15 11.0 0.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 NYD-SP28_assoc PF14775.1 EGG05214.1 - 0.23 11.1 1.1 2.9 7.6 0.2 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain Robl_LC7 PF03259.12 EGG05215.1 - 3.9e-05 23.1 0.0 5.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF605 PF04652.11 EGG05215.1 - 0.11 11.8 7.4 0.12 11.7 5.1 1.1 1 0 0 1 1 1 0 Vta1 like PMSI1 PF15322.1 EGG05215.1 - 0.12 11.4 3.8 0.16 11.0 2.6 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Catalase PF00199.14 EGG05216.1 - 5.6e-166 551.9 0.0 7e-166 551.6 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGG05216.1 - 1.2e-15 57.1 0.0 2.3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF3129 PF11327.3 EGG05219.1 - 7.2e-17 61.7 2.7 7.2e-17 61.7 1.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3129) Uds1 PF15456.1 EGG05222.1 - 3.7e-10 39.8 11.7 3.7e-10 39.8 8.1 9.4 4 4 6 10 10 10 4 Up-regulated During Septation Myosin_tail_1 PF01576.14 EGG05222.1 - 0.00012 20.0 15.1 0.00012 20.0 10.4 5.6 4 2 1 5 5 5 4 Myosin tail CENP-F_leu_zip PF10473.4 EGG05222.1 - 0.00023 21.0 20.7 0.00023 21.0 14.3 6.6 4 2 1 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EGG05222.1 - 0.00079 18.5 17.7 0.00079 18.5 12.2 6.5 3 2 2 6 6 6 2 Autophagy protein Apg6 JTB PF05439.7 EGG05223.1 - 7.3e-05 22.5 0.1 0.00023 20.9 0.1 1.8 1 0 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) COesterase PF00135.23 EGG05224.1 - 3.9e-80 270.0 0.0 5e-80 269.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGG05224.1 - 9.1e-09 35.1 0.0 3.1e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGG05224.1 - 5.3e-06 25.8 0.0 8.6e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EGG05224.1 - 0.0023 17.3 0.0 0.0057 16.1 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 EGG05224.1 - 0.0059 16.5 0.0 0.028 14.2 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG05224.1 - 0.0066 16.0 0.0 0.029 13.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGG05224.1 - 0.026 13.1 0.1 0.14 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGG05224.1 - 0.029 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 EGG05225.1 - 3.1e-76 257.1 0.0 4.1e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGG05225.1 - 8.3e-06 25.5 0.0 3.2e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGG05225.1 - 1.5e-05 24.3 0.0 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EGG05225.1 - 0.0023 17.4 0.0 0.0055 16.1 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 EGG05225.1 - 0.0074 16.1 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG05225.1 - 0.022 14.3 0.0 0.1 12.1 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG05225.1 - 0.059 13.1 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 EGG05226.1 - 5.3e-72 243.2 0.0 7e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGG05226.1 - 2.5e-05 23.9 0.0 6.5e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGG05226.1 - 0.00047 19.4 0.0 0.00077 18.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EGG05226.1 - 0.0045 16.4 0.0 0.0093 15.4 0.0 1.5 1 1 0 1 1 1 1 Putative esterase DUF2424 PF10340.4 EGG05226.1 - 0.012 14.3 0.1 0.027 13.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Abhydrolase_1 PF00561.15 EGG05226.1 - 0.043 13.3 0.0 0.99 8.9 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG05226.1 - 0.044 13.5 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family HATPase_c PF02518.21 EGG05229.1 - 1.1e-21 76.5 0.0 2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGG05229.1 - 6.9e-19 67.6 0.0 1.6e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EGG05229.1 - 1.6e-09 37.7 0.2 3e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_3 PF13589.1 EGG05229.1 - 0.0005 19.7 0.0 0.0012 18.5 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGG05229.1 - 0.029 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DnaJ PF00226.26 EGG05230.1 - 9.6e-20 70.0 1.8 1.7e-19 69.3 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGG05230.1 - 3.4e-13 49.2 0.0 3.5e-10 39.6 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGG05230.1 - 7.2e-12 45.1 8.3 1.1e-11 44.5 5.8 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGG05230.1 - 0.013 15.1 3.1 0.66 9.6 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family ESR1_C PF12743.2 EGG05230.1 - 0.029 13.8 0.7 0.051 13.1 0.5 1.4 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal TSKS PF15358.1 EGG05230.1 - 0.15 10.1 0.1 0.21 9.7 0.0 1.2 1 0 0 1 1 1 0 Testis-specific serine kinase substrate DUF2217 PF10265.4 EGG05231.1 - 0.43 9.2 6.3 0.82 8.3 4.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DDHD PF02862.12 EGG05232.1 - 0.81 9.4 6.7 1.4 8.6 4.7 1.4 1 0 0 1 1 1 0 DDHD domain DUF2215 PF10225.4 EGG05232.1 - 10 5.5 7.7 0.38 10.1 1.4 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Alk_phosphatase PF00245.15 EGG05233.1 - 4e-83 279.4 0.0 5.8e-83 278.9 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase DUF3287 PF11690.3 EGG05234.1 - 0.084 12.9 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Mpv17_PMP22 PF04117.7 EGG05235.1 - 3.9e-22 77.6 0.1 9.1e-22 76.4 0.0 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Sugar_tr PF00083.19 EGG05236.1 - 2.8e-106 355.7 27.3 3.3e-106 355.5 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG05236.1 - 8e-16 57.6 37.6 1.1e-10 40.7 7.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGG05236.1 - 0.00034 18.8 1.2 0.0011 17.1 0.1 2.2 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family AAA PF00004.24 EGG05237.1 - 6.3e-44 149.3 0.0 1.3e-43 148.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EGG05237.1 - 1.2e-07 31.8 0.0 2.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EGG05237.1 - 1.1e-06 28.4 0.0 5.9e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGG05237.1 - 2.3e-06 27.7 0.0 9.6e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGG05237.1 - 3.7e-06 27.1 0.1 0.00027 21.0 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EGG05237.1 - 7.2e-05 22.4 0.1 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EGG05237.1 - 0.00012 21.2 0.0 0.00022 20.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGG05237.1 - 0.00013 22.7 0.0 0.00027 21.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGG05237.1 - 0.00042 19.7 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EGG05237.1 - 0.0012 17.6 0.0 0.0024 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EGG05237.1 - 0.0016 18.3 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGG05237.1 - 0.0025 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGG05237.1 - 0.003 16.7 0.0 0.0059 15.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EGG05237.1 - 0.0036 17.2 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EGG05237.1 - 0.006 15.8 0.0 0.071 12.3 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.6 EGG05237.1 - 0.0061 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EGG05237.1 - 0.0073 15.4 0.1 0.016 14.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EGG05237.1 - 0.0091 16.3 0.0 0.031 14.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain KaiC PF06745.8 EGG05237.1 - 0.016 14.3 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.1 EGG05237.1 - 0.018 14.6 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain KLRAQ PF10205.4 EGG05237.1 - 0.018 15.0 0.7 0.018 15.0 0.5 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Histone PF00125.19 EGG05237.1 - 0.019 15.0 0.1 0.057 13.5 0.1 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activat PF00158.21 EGG05237.1 - 0.022 14.2 0.0 0.1 12.0 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF2072 PF09845.4 EGG05237.1 - 0.026 14.4 0.1 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DUF815 PF05673.8 EGG05237.1 - 0.029 13.2 0.0 0.058 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EGG05237.1 - 0.029 13.7 0.1 0.092 12.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 EGG05237.1 - 0.037 13.6 0.0 0.55 9.8 0.0 2.2 1 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EGG05237.1 - 0.041 14.0 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 EGG05237.1 - 0.053 12.3 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EGG05237.1 - 0.056 13.4 0.0 0.2 11.7 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 EGG05237.1 - 0.11 12.1 0.0 0.29 10.6 0.0 1.8 2 1 0 2 2 2 0 AAA domain DivIC PF04977.10 EGG05237.1 - 0.13 11.8 3.0 0.11 11.9 0.6 2.0 2 0 0 2 2 2 0 Septum formation initiator CENP-X PF09415.5 EGG05239.1 - 2.5e-09 36.8 0.0 3.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 CENP-S associating Centromere protein X AAA PF00004.24 EGG05240.1 - 1.1e-11 45.0 0.0 2.6e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EGG05240.1 - 1.3e-07 30.7 0.2 0.002 16.9 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EGG05240.1 - 1.3e-06 28.5 0.1 4.2e-06 26.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EGG05240.1 - 2.6e-05 24.1 0.0 5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGG05240.1 - 8.8e-05 21.6 0.0 0.00017 20.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EGG05240.1 - 0.00012 21.9 0.0 0.00065 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EGG05240.1 - 0.00016 21.6 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EGG05240.1 - 0.00028 21.7 0.0 0.00086 20.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGG05240.1 - 0.00035 20.3 0.0 0.00064 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EGG05240.1 - 0.0012 18.4 0.1 0.0024 17.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGG05240.1 - 0.0042 16.1 0.0 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EGG05240.1 - 0.011 15.1 0.1 0.26 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EGG05240.1 - 0.012 15.3 0.1 0.028 14.1 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EGG05240.1 - 0.014 15.7 0.0 0.06 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGG05240.1 - 0.02 14.9 0.0 0.36 10.8 0.0 2.6 1 1 1 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EGG05240.1 - 0.025 13.7 0.0 0.062 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EGG05240.1 - 0.03 13.7 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 EGG05240.1 - 0.042 13.8 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EGG05240.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EGG05240.1 - 0.069 13.3 0.0 0.27 11.4 0.0 2.0 2 0 0 2 2 1 0 RNA helicase KaiC PF06745.8 EGG05240.1 - 0.081 12.0 0.0 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 KaiC KTI12 PF08433.5 EGG05240.1 - 0.13 11.4 0.0 0.34 10.0 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 IF4E PF01652.13 EGG05241.1 - 3.6e-44 150.2 0.0 5.3e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PEP-utilisers_N PF05524.8 EGG05242.1 - 0.0028 17.4 0.3 0.0072 16.1 0.2 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal Sporozoite_P67 PF05642.6 EGG05242.1 - 0.0038 15.1 10.2 0.0087 13.9 7.1 1.6 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CDC45 PF02724.9 EGG05242.1 - 0.023 12.7 11.6 0.031 12.3 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Bap31 PF05529.7 EGG05242.1 - 0.035 13.5 0.0 0.035 13.5 0.0 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Nop14 PF04147.7 EGG05242.1 - 0.1 10.5 16.8 0.14 10.0 11.6 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 EGG05242.1 - 1.1 8.6 14.0 2 7.7 9.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 EGG05242.1 - 1.9 7.4 20.2 4.1 6.3 14.0 1.5 1 0 0 1 1 1 0 BUD22 Ycf1 PF05758.7 EGG05242.1 - 5.1 4.6 5.9 6.8 4.2 4.1 1.1 1 0 0 1 1 1 0 Ycf1 DUF4140 PF13600.1 EGG05242.1 - 7.4 7.0 9.3 0.23 11.9 0.3 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SDA1 PF05285.7 EGG05242.1 - 8.9 5.4 17.8 16 4.6 12.3 1.3 1 0 0 1 1 1 0 SDA1 DAHP_synth_1 PF00793.15 EGG05246.1 - 2.3e-44 151.1 0.1 3.6e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 DAHP synthetase I family TRAM1 PF08390.6 EGG05248.1 - 0.065 12.7 0.1 0.19 11.2 0.1 1.8 1 0 0 1 1 1 0 TRAM1-like protein Pil1 PF13805.1 EGG05249.1 - 1.3e-24 86.7 0.1 2.4e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 CENP-F_leu_zip PF10473.4 EGG05249.1 - 0.0019 18.0 4.0 0.0034 17.2 2.8 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC144C PF14915.1 EGG05249.1 - 0.013 14.4 1.1 0.013 14.4 0.8 1.6 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Phage_GP20 PF06810.6 EGG05249.1 - 0.021 14.2 0.4 0.037 13.4 0.3 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 ATG16 PF08614.6 EGG05249.1 - 0.056 13.2 1.0 0.1 12.4 0.7 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) BRE1 PF08647.6 EGG05249.1 - 0.078 12.9 2.6 0.061 13.2 0.6 1.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Vps5 PF09325.5 EGG05249.1 - 0.093 11.9 2.5 0.83 8.8 0.5 2.1 2 0 0 2 2 2 0 Vps5 C terminal like Snapin_Pallidin PF14712.1 EGG05249.1 - 0.12 12.7 0.5 0.27 11.5 0.3 1.6 1 0 0 1 1 1 0 Snapin/Pallidin Aminotran_5 PF00266.14 EGG05250.1 - 1.7e-34 119.1 0.0 6.6e-34 117.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V zf-RING_2 PF13639.1 EGG05251.1 - 2.8e-13 49.4 2.7 8.3e-13 47.9 1.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGG05251.1 - 5.5e-07 29.6 1.0 1.2e-06 28.4 0.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGG05251.1 - 6.5e-06 26.0 4.9 1.8e-05 24.6 3.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EGG05251.1 - 0.00075 19.4 5.0 0.0013 18.6 2.6 2.1 2 1 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 EGG05251.1 - 0.0018 17.9 3.2 0.0044 16.6 2.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGG05251.1 - 0.002 17.9 0.4 0.0045 16.7 0.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EGG05251.1 - 0.0035 16.9 4.0 0.013 15.1 2.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGG05251.1 - 0.004 16.8 4.5 0.0044 16.7 1.6 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Baculo_RING PF05883.6 EGG05251.1 - 0.008 16.0 0.7 0.024 14.4 0.5 1.8 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain DUF4462 PF14692.1 EGG05251.1 - 0.0084 15.3 0.0 0.018 14.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4462) RINGv PF12906.2 EGG05251.1 - 0.036 14.1 3.7 0.082 12.9 2.6 1.7 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 EGG05251.1 - 0.072 12.7 3.4 0.17 11.6 2.4 1.7 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 EGG05251.1 - 0.076 12.8 3.1 0.2 11.5 2.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING C1_1 PF00130.17 EGG05251.1 - 0.28 10.9 3.6 0.22 11.3 0.7 2.2 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 EGG05251.1 - 0.54 10.0 5.9 0.41 10.4 2.7 1.9 2 0 0 2 2 1 0 zinc-RING finger domain zf-C2H2 PF00096.21 EGG05252.1 - 1.9e-05 24.7 2.5 0.068 13.5 0.0 2.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG05252.1 - 0.001 19.2 4.4 0.042 14.1 0.0 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 EGG05252.1 - 0.005 16.9 0.9 0.73 10.0 0.2 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EGG05252.1 - 0.013 15.6 3.5 0.38 10.9 0.3 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Sgf11 PF08209.6 EGG05252.1 - 0.088 12.1 1.1 0.17 11.2 0.1 1.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DZR PF12773.2 EGG05252.1 - 0.15 11.8 0.9 0.28 11.0 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.16 EGG05253.1 - 1.2e-07 31.4 37.9 3.9e-05 23.4 6.1 3.8 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EGG05253.1 - 0.0072 16.3 8.6 0.0072 16.3 6.0 4.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Transcrip_reg PF01709.15 EGG05253.1 - 0.098 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Exo_endo_phos PF03372.18 EGG05254.1 - 3.6e-18 66.4 0.2 5.4e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2207 PF09972.4 EGG05254.1 - 0.19 10.2 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SNARE PF05739.14 EGG05255.1 - 1.1e-10 41.0 5.5 1.4e-10 40.6 3.8 1.1 1 0 0 1 1 1 1 SNARE domain Activator-TraM PF11657.3 EGG05255.1 - 0.032 13.7 1.0 0.038 13.4 0.7 1.2 1 0 0 1 1 1 0 Transcriptional activator TraM DUF745 PF05335.8 EGG05255.1 - 0.13 11.7 1.2 0.16 11.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF2884 PF11101.3 EGG05255.1 - 0.18 11.1 2.5 0.23 10.8 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Snapin_Pallidin PF14712.1 EGG05255.1 - 0.25 11.6 3.5 0.56 10.5 2.4 1.6 1 1 0 1 1 1 0 Snapin/Pallidin Fusion_gly PF00523.13 EGG05255.1 - 0.39 8.7 2.3 2.6 5.9 0.4 1.9 1 1 1 2 2 2 0 Fusion glycoprotein F0 TRAM_LAG1_CLN8 PF03798.11 EGG05256.1 - 1.4e-34 119.3 16.8 1.8e-34 119.0 11.7 1.2 1 0 0 1 1 1 1 TLC domain TRAM_LAG1_CLN8 PF03798.11 EGG05257.1 - 1.3e-32 112.9 19.7 2.1e-32 112.3 13.7 1.3 1 0 0 1 1 1 1 TLC domain CDP-OH_P_transf PF01066.16 EGG05258.1 - 1.2e-13 51.2 0.5 1.2e-13 51.2 0.4 3.1 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.20 EGG05259.1 - 1.1e-75 254.1 0.0 1.4e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG05259.1 - 1.6e-37 129.0 0.0 2e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG05259.1 - 4.6e-05 22.5 0.0 7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EGG05259.1 - 0.00084 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EGG05259.1 - 0.0093 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PACT_coil_coil PF10495.4 EGG05259.1 - 0.028 14.3 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein PYRIN PF02758.11 EGG05259.1 - 0.072 12.7 0.7 0.97 9.1 0.2 2.5 3 0 0 3 3 3 0 PAAD/DAPIN/Pyrin domain LRR_4 PF12799.2 EGG05260.1 - 0.0036 16.8 0.8 10 5.8 0.0 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) UQ_con PF00179.21 EGG05261.1 - 8.8e-38 128.8 0.0 1.1e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EGG05261.1 - 0.018 14.7 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain adh_short PF00106.20 EGG05263.1 - 0.13 12.2 0.0 5.1 6.9 0.0 2.9 3 0 0 3 3 3 0 short chain dehydrogenase Peptidase_M3 PF01432.15 EGG05265.1 - 1.1e-129 433.4 0.0 1.5e-129 433.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_C93 PF06035.6 EGG05266.1 - 0.13 11.7 0.2 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 Bacterial transglutaminase-like cysteine proteinase BTLCP RRM_1 PF00076.17 EGG05267.1 - 3.7e-05 23.2 0.0 6.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG05267.1 - 0.024 14.6 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 EGG05267.1 - 0.096 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding RhoGAP PF00620.22 EGG05270.1 - 0.017 14.7 0.1 0.079 12.5 0.0 1.9 1 1 1 2 2 2 0 RhoGAP domain Slu7 PF11708.3 EGG05272.1 - 1.5e-72 244.1 22.2 1.5e-72 244.1 15.4 2.7 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EGG05272.1 - 0.038 13.6 0.4 0.085 12.5 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4448 PF14610.1 EGG05273.1 - 0.01 15.3 0.2 0.025 14.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EGG05273.1 - 0.67 9.6 0.0 0.67 9.6 0.0 2.8 3 0 0 3 3 3 0 TMEM154 protein family Ribosomal_S17e PF00833.13 EGG05274.1 - 7.7e-59 196.7 0.1 9.2e-59 196.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 AFG1_ATPase PF03969.11 EGG05276.1 - 1.9e-50 171.7 0.0 9.2e-49 166.1 0.0 2.0 2 0 0 2 2 2 1 AFG1-like ATPase AAA_16 PF13191.1 EGG05276.1 - 0.0013 18.7 0.4 0.018 15.0 0.0 2.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EGG05276.1 - 0.0018 18.0 0.1 0.026 14.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGG05276.1 - 0.0051 16.7 0.0 0.028 14.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EGG05276.1 - 0.018 15.2 0.0 0.081 13.1 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGG05276.1 - 0.02 14.9 0.0 0.14 12.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGG05276.1 - 0.046 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.4 EGG05276.1 - 0.052 12.5 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CaATP_NAI PF12515.3 EGG05276.1 - 0.091 12.2 0.2 0.97 8.9 0.0 2.4 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain AAA_19 PF13245.1 EGG05276.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Evr1_Alr PF04777.8 EGG05277.1 - 6.9e-29 99.6 0.8 6.9e-29 99.6 0.6 1.6 2 0 0 2 2 2 1 Erv1 / Alr family RabGAP-TBC PF00566.13 EGG05279.1 - 1.9e-32 112.4 0.0 2.5e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Clp1 PF06807.9 EGG05280.1 - 6.8e-23 81.4 0.0 9.2e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EGG05280.1 - 0.00029 20.5 0.1 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EGG05280.1 - 0.00058 19.3 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EGG05280.1 - 0.012 15.4 0.3 0.09 12.5 0.3 2.1 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.18 EGG05280.1 - 0.014 15.3 0.1 0.57 10.1 0.1 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EGG05280.1 - 0.024 14.6 0.5 0.054 13.4 0.2 1.7 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EGG05280.1 - 0.067 13.6 0.2 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 Miro-like protein ATP_bind_1 PF03029.12 EGG05280.1 - 0.11 12.0 0.1 1.2 8.5 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EGG05280.1 - 0.14 12.4 0.2 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 ABC transporter Septin PF00735.13 EGG05280.1 - 0.25 10.3 0.0 0.38 9.7 0.0 1.2 1 0 0 1 1 1 0 Septin TPR_11 PF13414.1 EGG05281.1 - 3.3e-12 45.8 0.5 3e-10 39.6 0.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EGG05281.1 - 2.1e-09 36.5 2.3 0.0004 19.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGG05281.1 - 1.3e-06 27.8 0.4 0.022 14.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF2312 PF10073.4 EGG05281.1 - 0.033 13.5 0.6 0.033 13.5 0.4 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) TPR_12 PF13424.1 EGG05281.1 - 0.065 13.1 0.5 3.9 7.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MtrB PF05440.7 EGG05281.1 - 0.094 12.7 0.1 0.78 9.8 0.0 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B TPR_19 PF14559.1 EGG05281.1 - 0.17 12.2 0.5 7.8 6.9 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Arrestin_C PF02752.17 EGG05282.1 - 1.8e-05 24.8 0.0 0.029 14.4 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGG05282.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain TPR_2 PF07719.12 EGG05283.1 - 2e-25 86.5 13.4 0.0018 18.0 0.4 9.4 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 EGG05283.1 - 4.6e-25 87.0 7.5 3.2e-08 33.0 0.1 6.9 6 1 1 7 7 7 5 TPR repeat Apc3 PF12895.2 EGG05283.1 - 8e-23 80.3 9.1 1.3e-08 34.8 0.0 6.8 6 1 1 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGG05283.1 - 2.4e-18 65.8 11.5 1.2e-07 31.5 0.1 7.4 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGG05283.1 - 3.5e-17 61.2 6.3 0.0036 16.8 0.3 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGG05283.1 - 6.8e-14 50.5 0.8 0.00034 20.1 0.1 6.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGG05283.1 - 1.3e-10 41.5 15.5 0.019 15.6 1.3 7.9 7 1 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGG05283.1 - 2.7e-10 39.6 3.4 0.31 11.3 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGG05283.1 - 3e-09 37.0 3.4 0.17 12.2 0.0 6.3 6 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGG05283.1 - 1.4e-08 34.6 18.5 2.5 8.9 0.0 9.6 8 3 3 11 11 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGG05283.1 - 2.7e-07 30.5 14.3 3.7 8.2 0.3 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG05283.1 - 7.8e-07 28.4 7.1 2.4 8.1 0.2 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGG05283.1 - 1.9e-05 24.4 10.3 0.23 11.4 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGG05283.1 - 0.0028 17.4 12.7 0.0079 16.0 0.3 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EGG05283.1 - 1.6 9.4 6.9 30 5.4 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat FliP PF00813.15 EGG05284.1 - 0.011 15.4 0.5 0.02 14.5 0.3 1.4 1 0 0 1 1 1 0 FliP family T-box PF00907.17 EGG05286.1 - 0.13 11.7 0.0 7 6.0 0.0 2.1 2 0 0 2 2 2 0 T-box DUF3296 PF11726.3 EGG05287.1 - 0.034 13.7 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) Helitron_like_N PF14214.1 EGG05287.1 - 0.072 12.8 0.1 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Helitron helicase-like domain at N-terminus Rhodanese PF00581.15 EGG05289.1 - 0.038 14.3 0.0 0.066 13.5 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain F-box-like PF12937.2 EGG05289.1 - 0.75 9.5 3.5 0.59 9.9 0.5 2.3 2 1 0 2 2 2 0 F-box-like TRAPP PF04051.11 EGG05297.1 - 3.3e-32 111.1 0.0 4e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DNA_primase_S PF01896.14 EGG05300.1 - 1.4e-15 57.3 0.1 2.2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF1090 PF06476.7 EGG05300.1 - 0.039 13.6 1.3 0.19 11.3 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) Peptidase_C39 PF03412.10 EGG05300.1 - 0.057 13.2 0.1 0.089 12.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase C39 family Occludin_ELL PF07303.8 EGG05300.1 - 0.13 12.9 3.6 0.083 13.6 1.3 1.6 2 0 0 2 2 2 0 Occludin homology domain DUF2046 PF09755.4 EGG05301.1 - 0.041 12.7 0.2 0.057 12.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) GPI-anchored PF10342.4 EGG05302.1 - 1.6e-13 50.9 2.6 1.6e-13 50.9 1.8 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mucin PF01456.12 EGG05302.1 - 6.3 6.5 10.5 7.9 6.2 7.2 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein Uds1 PF15456.1 EGG05306.1 - 0.035 14.0 1.3 0.042 13.8 0.6 1.3 1 1 0 1 1 1 0 Up-regulated During Septation DUF1515 PF07439.6 EGG05306.1 - 0.089 12.6 1.3 0.1 12.4 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DUF3192 PF11399.3 EGG05306.1 - 0.098 12.5 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Sigma70_ner PF04546.8 EGG05312.1 - 0.62 9.6 12.6 1.4 8.4 8.8 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region TT_ORF2 PF02957.10 EGG05312.1 - 4.1 8.1 11.9 1.5 9.5 5.3 2.5 2 0 0 2 2 2 0 TT viral ORF2 PPP4R2 PF09184.6 EGG05312.1 - 6.9 6.1 22.6 0.22 11.0 9.4 2.6 2 0 0 2 2 2 0 PPP4R2 B_lectin PF01453.19 EGG05313.1 - 2.7e-13 49.8 1.1 5.6e-08 32.6 1.0 2.8 2 1 0 2 2 2 2 D-mannose binding lectin GATA PF00320.22 EGG05313.1 - 0.024 13.9 0.1 0.062 12.6 0.1 1.7 1 0 0 1 1 1 0 GATA zinc finger DUF2418 PF10332.4 EGG05316.1 - 3.5e-24 84.9 1.6 5.7e-24 84.3 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) EF-1_beta_acid PF10587.4 EGG05318.1 - 4.1 7.6 7.7 7.4 6.8 5.4 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region HSF_DNA-bind PF00447.12 EGG05319.1 - 7.1e-34 116.0 8.1 7.1e-34 116.0 5.6 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 EGG05319.1 - 4.2e-23 81.4 0.0 9.8e-23 80.3 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain IMS PF00817.15 EGG05319.1 - 0.078 12.7 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 impB/mucB/samB family Lipoprotein_17 PF04200.7 EGG05319.1 - 5.1 7.3 9.1 18 5.5 0.6 3.2 2 0 0 2 2 2 0 Lipoprotein associated domain MBOAT_2 PF13813.1 EGG05320.1 - 3.2e-08 33.5 8.7 3.2e-08 33.5 6.1 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family SRP40_C PF05022.7 EGG05321.1 - 3.3e-28 97.9 1.3 3.3e-28 97.9 0.9 1.7 2 0 0 2 2 2 1 SRP40, C-terminal domain WD40 PF00400.27 EGG05322.1 - 2.2e-51 169.9 17.1 4.9e-10 38.9 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EGG05322.1 - 9.8e-10 38.0 0.2 2.1e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGG05322.1 - 1.2e-07 31.2 0.4 2.5e-07 30.1 0.1 1.7 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 EGG05322.1 - 1.1e-05 23.7 8.8 0.51 8.4 1.0 5.2 4 1 0 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGG05322.1 - 0.00025 19.9 0.8 3.4 6.2 0.1 4.6 3 2 1 4 4 4 2 Nup133 N terminal like PQQ_2 PF13360.1 EGG05322.1 - 0.00044 19.7 3.7 0.21 11.0 0.2 3.1 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 EGG05322.1 - 0.1 12.9 8.2 2.1 8.7 0.2 5.1 5 1 0 5 5 5 0 PQQ-like domain PQQ PF01011.16 EGG05322.1 - 0.15 11.6 2.5 2.4 7.8 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat UPF0029 PF01205.14 EGG05323.1 - 4e-30 103.7 0.1 7.3e-30 102.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EGG05323.1 - 1.3e-08 34.7 1.1 2.8e-08 33.6 0.8 1.6 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 EGG05323.1 - 0.01 15.2 0.2 0.17 11.3 0.0 2.5 2 1 0 2 2 2 0 Ubiquitin-conjugating enzyme RIC1 PF07064.8 EGG05324.1 - 3.3e-37 128.3 0.2 5.3e-37 127.6 0.1 1.2 1 0 0 1 1 1 1 RIC1 Got1 PF04178.7 EGG05325.1 - 3e-27 95.0 21.1 4.4e-27 94.5 14.6 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Claudin_2 PF13903.1 EGG05325.1 - 0.0051 16.5 3.1 0.0051 16.5 2.2 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Peptidase_M50 PF02163.17 EGG05325.1 - 0.13 11.2 1.1 0.32 9.9 0.7 1.7 1 1 0 1 1 1 0 Peptidase family M50 ABC2_membrane_4 PF12730.2 EGG05325.1 - 0.71 8.9 23.5 0.044 12.9 4.2 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein PBC PF03792.8 EGG05326.1 - 0.029 14.0 0.9 0.056 13.1 0.6 1.4 1 0 0 1 1 1 0 PBC domain TT_ORF2 PF02957.10 EGG05326.1 - 0.24 12.0 6.9 0.68 10.6 4.8 1.7 1 0 0 1 1 1 0 TT viral ORF2 DUF1168 PF06658.7 EGG05326.1 - 2.6 7.5 14.1 5.3 6.5 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) HEM4 PF02602.10 EGG05327.1 - 1.6e-13 50.4 0.0 6.5e-11 41.9 0.0 2.1 2 0 0 2 2 2 2 Uroporphyrinogen-III synthase HemD Sod_Fe_C PF02777.13 EGG05330.1 - 5.3e-32 109.8 0.7 9.2e-32 109.0 0.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGG05330.1 - 2e-28 98.4 1.5 2.5e-28 98.1 0.2 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 EGG05331.1 - 1.8e-29 101.6 0.1 2.9e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGG05331.1 - 2.6e-28 98.0 0.7 5.2e-28 97.1 0.5 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain PGAP1 PF07819.8 EGG05333.1 - 0.0087 15.6 0.0 0.019 14.5 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGG05333.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EGG05333.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_2 PF01674.13 EGG05333.1 - 0.032 13.5 0.0 1.3 8.2 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 2) DUF915 PF06028.6 EGG05333.1 - 0.036 13.1 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 EGG05333.1 - 0.066 12.7 0.1 0.22 11.0 0.0 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGG05333.1 - 0.076 12.8 0.0 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.6 EGG05333.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal LCAT PF02450.10 EGG05333.1 - 0.14 11.1 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase 2OG-FeII_Oxy_2 PF13532.1 EGG05334.1 - 7.1e-11 42.2 0.0 1.3e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp_Arg_Hydrox PF05118.10 EGG05334.1 - 0.034 13.9 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase 2OG-FeII_Oxy_2 PF13532.1 EGG05335.1 - 0.014 15.2 0.0 0.11 12.2 0.0 2.2 3 0 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily DAHP_synth_1 PF00793.15 EGG05338.1 - 1.1e-84 283.3 0.0 3.1e-83 278.5 0.0 2.0 1 1 0 1 1 1 1 DAHP synthetase I family Abhydrolase_3 PF07859.8 EGG05339.1 - 1.8e-11 44.0 0.0 2.5e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG05339.1 - 1.1e-10 41.4 0.0 1.7e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EGG05339.1 - 6e-10 38.4 0.9 2.6e-09 36.3 0.6 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EGG05339.1 - 5.7e-07 29.6 0.3 1.3e-06 28.4 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGG05339.1 - 0.00074 18.7 0.1 0.029 13.6 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EGG05339.1 - 0.0027 16.6 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 EGG05339.1 - 0.14 11.6 0.0 7.7 5.8 0.0 2.8 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Methyltransf_11 PF08241.7 EGG05340.1 - 2.1e-17 63.3 0.0 3.7e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG05340.1 - 1.8e-15 56.8 0.0 2.5e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG05340.1 - 3.5e-14 53.3 0.0 6.7e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG05340.1 - 1.4e-10 41.5 0.0 2.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG05340.1 - 6e-10 39.0 0.0 8.7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG05340.1 - 2.3e-09 37.4 0.0 4.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGG05340.1 - 6.3e-07 28.7 0.0 9.7e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGG05340.1 - 4.8e-06 26.0 0.0 1.1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EGG05340.1 - 3e-05 23.2 0.0 4.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGG05340.1 - 0.00012 22.0 0.0 0.00084 19.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGG05340.1 - 0.0039 16.7 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EGG05340.1 - 0.01 14.8 0.0 0.033 13.2 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Spermine_synth PF01564.12 EGG05340.1 - 0.013 14.4 0.0 1.5 7.6 0.0 2.1 1 1 1 2 2 2 0 Spermine/spermidine synthase N6_N4_Mtase PF01555.13 EGG05340.1 - 0.036 13.5 0.0 2.1 7.7 0.0 2.1 2 0 0 2 2 2 0 DNA methylase Methyltransf_PK PF05891.7 EGG05340.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase FmrO PF07091.6 EGG05340.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) FAD-oxidase_C PF02913.14 EGG05342.1 - 3.4e-53 180.5 0.0 4.4e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGG05342.1 - 8.3e-23 80.3 0.0 2.4e-20 72.4 0.0 2.5 2 1 0 2 2 2 1 FAD binding domain Amidohydro_3 PF07969.6 EGG05343.1 - 7.6e-61 206.5 0.0 8.9e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EGG05343.1 - 0.00014 21.6 0.0 0.072 12.7 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EGG05343.1 - 0.00033 20.3 0.0 0.00096 18.9 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase SET PF00856.23 EGG05344.1 - 3.4e-19 69.7 0.1 3.4e-19 69.7 0.0 3.0 2 2 0 2 2 2 1 SET domain SRI PF08236.6 EGG05344.1 - 3.7e-15 55.6 2.0 1e-14 54.2 1.4 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 EGG05344.1 - 2.8e-06 26.7 1.8 6.9e-06 25.4 0.5 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain WW PF00397.21 EGG05344.1 - 1.3e-05 24.9 0.5 2.7e-05 23.9 0.3 1.6 1 0 0 1 1 1 1 WW domain DUF1191 PF06697.7 EGG05345.1 - 0.08 11.7 0.4 0.13 11.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) Nop14 PF04147.7 EGG05346.1 - 0.00064 17.7 19.6 0.001 17.1 13.6 1.3 1 0 0 1 1 1 1 Nop14-like family DUF2146 PF10220.4 EGG05346.1 - 0.91 7.4 22.9 0.014 13.3 11.1 1.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2146) SDA1 PF05285.7 EGG05346.1 - 2 7.6 22.9 4.4 6.4 15.9 1.6 1 1 0 1 1 1 0 SDA1 AMP-binding PF00501.23 EGG05347.1 - 8e-73 245.2 0.0 1e-72 244.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGG05347.1 - 4.3e-05 24.3 0.0 0.00021 22.1 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Thioredoxin PF00085.15 EGG05348.1 - 3.1e-59 197.0 2.5 3.4e-28 97.3 0.0 3.8 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EGG05348.1 - 1.3e-41 142.4 6.1 9.2e-33 113.5 2.6 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGG05348.1 - 1.3e-09 37.9 0.0 0.00022 21.1 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EGG05348.1 - 1.1e-08 35.0 5.8 0.0027 17.8 0.0 4.8 5 1 1 6 6 6 3 Thioredoxin-like Thioredoxin_2 PF13098.1 EGG05348.1 - 3.8e-08 33.5 8.2 0.001 19.2 0.2 5.1 4 2 0 4 4 4 2 Thioredoxin-like domain Calsequestrin PF01216.12 EGG05348.1 - 3.2e-06 26.1 0.7 3.2e-06 26.1 0.5 1.7 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_4 PF13462.1 EGG05348.1 - 3.6e-05 23.8 0.5 0.37 10.7 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin AhpC-TSA PF00578.16 EGG05348.1 - 0.0017 18.0 3.9 0.65 9.6 0.1 3.7 4 1 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 EGG05348.1 - 0.0023 17.4 0.3 0.4 10.2 0.0 3.1 3 0 0 3 3 3 1 Redoxin Thioredoxin_9 PF14595.1 EGG05348.1 - 0.039 13.5 0.1 5.1 6.6 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin Ank_2 PF12796.2 EGG05350.1 - 2.1e-50 169.0 8.7 1.2e-19 70.3 0.1 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EGG05350.1 - 5.8e-37 123.6 11.4 4.2e-09 35.7 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat zf-DHHC PF01529.15 EGG05350.1 - 2.6e-36 124.6 3.3 5.1e-36 123.6 2.3 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_4 PF13637.1 EGG05350.1 - 4.2e-30 103.5 2.1 1.7e-10 41.1 0.1 3.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGG05350.1 - 1.8e-24 85.2 7.3 1.2e-08 34.9 0.1 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGG05350.1 - 6.5e-24 81.6 5.6 6.8e-06 25.8 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat stn_TNFRSF12A PF12191.3 EGG05350.1 - 0.033 14.2 1.1 0.08 12.9 0.8 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain RWD PF05773.17 EGG05351.1 - 7.3e-11 41.9 0.3 1.4e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 RWD domain Polysacc_lyase PF14099.1 EGG05352.1 - 0.094 12.3 0.7 0.2 11.3 0.1 1.6 2 0 0 2 2 2 0 Polysaccharide lyase SH3_9 PF14604.1 EGG05353.1 - 1.2e-05 24.7 0.0 2.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SOBP PF15279.1 EGG05353.1 - 0.0029 18.0 40.5 0.0029 18.0 28.0 3.1 3 0 0 3 3 3 1 Sine oculis-binding protein UQ_con PF00179.21 EGG05354.1 - 2.2e-37 127.6 0.0 2.7e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MBOAT_2 PF13813.1 EGG05355.1 - 3.3e-11 43.1 3.9 6.1e-11 42.2 2.7 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CTP_transf_2 PF01467.21 EGG05357.1 - 1.4e-16 60.9 0.0 2e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase FGE-sulfatase PF03781.11 EGG05357.1 - 0.043 13.1 0.2 0.059 12.7 0.1 1.1 1 0 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 TBP PF00352.16 EGG05358.1 - 3e-70 231.5 0.3 2e-35 119.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EGG05358.1 - 0.00013 21.9 0.0 0.5 10.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Peptidase_M10 PF00413.19 EGG05360.1 - 0.0019 17.9 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Matrixin Pro_CA PF00484.14 EGG05361.1 - 6.5e-46 156.1 1.1 7.4e-46 155.9 0.7 1.0 1 0 0 1 1 1 1 Carbonic anhydrase Fucokinase PF07959.7 EGG05361.1 - 0.092 11.2 0.3 0.14 10.7 0.1 1.3 1 1 0 1 1 1 0 L-fucokinase Hema_esterase PF03996.10 EGG05362.1 - 0.036 13.2 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Hemagglutinin esterase EF-1_beta_acid PF10587.4 EGG05363.1 - 0.056 13.6 3.7 0.15 12.2 2.6 1.8 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region MoaE PF02391.12 EGG05364.1 - 0.12 12.1 0.0 0.38 10.5 0.0 1.8 1 0 0 1 1 1 0 MoaE protein Brevenin PF03032.10 EGG05364.1 - 0.3 10.9 2.2 1.2 9.0 0.4 2.4 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family Tox-REase-3 PF15647.1 EGG05365.1 - 0.038 13.7 2.3 0.043 13.6 1.6 1.1 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 Trypsin PF00089.21 EGG05368.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Trypsin Nop52 PF05997.7 EGG05369.1 - 0.081 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleolar protein,Nop52 Kinesin PF00225.18 EGG05370.1 - 4.4e-98 328.0 3.7 4.4e-98 328.0 2.6 2.4 2 0 0 2 2 2 1 Kinesin motor domain ERM PF00769.14 EGG05370.1 - 0.0023 17.4 6.4 0.0023 17.4 4.4 9.0 5 2 3 8 8 8 3 Ezrin/radixin/moesin family DGCR6 PF07324.6 EGG05374.1 - 1.3e-06 28.0 5.9 8.2e-06 25.4 4.1 1.9 1 1 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.4 EGG05374.1 - 2.6e-05 24.1 4.8 6.9e-05 22.7 3.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2458) Cohesin_HEAT PF12765.2 EGG05374.1 - 0.019 14.9 0.2 0.066 13.1 0.1 1.9 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion WW PF00397.21 EGG05375.1 - 1.3e-05 24.8 4.6 5.3e-05 22.9 3.2 2.1 1 0 0 1 1 1 1 WW domain Daxx PF03344.10 EGG05375.1 - 3.1 6.1 24.3 3.2 6.1 16.8 1.1 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 EGG05375.1 - 6.1 4.5 19.7 10 3.8 13.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ycf1 PF05758.7 EGG05375.1 - 8 4.0 14.2 9.9 3.7 9.8 1.2 1 0 0 1 1 1 0 Ycf1 TFIIF_alpha PF05793.7 EGG05375.1 - 9.1 4.5 35.9 14 3.8 24.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Kelch_2 PF07646.10 EGG05376.1 - 0.12 12.1 1.1 16 5.4 0.0 2.5 2 0 0 2 2 2 0 Kelch motif DUF605 PF04652.11 EGG05376.1 - 7 5.9 15.3 1.7 7.9 0.7 2.2 2 0 0 2 2 2 0 Vta1 like Alpha_kinase PF02816.13 EGG05378.1 - 0.00011 21.8 0.0 0.00025 20.7 0.0 1.5 1 1 0 1 1 1 1 Alpha-kinase family DEAD PF00270.24 EGG05379.1 - 1.1e-23 83.5 0.0 2.2e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG05379.1 - 6.4e-10 38.7 0.4 5.2e-09 35.8 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CDT1 PF08839.6 EGG05379.1 - 4.4e-05 23.4 0.1 9.4e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like Ribosomal_S16 PF00886.14 EGG05380.1 - 5e-19 67.7 0.0 9.1e-19 66.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 Thionin PF00321.12 EGG05382.1 - 0.95 9.7 4.4 25 5.1 0.0 2.6 2 1 0 2 2 2 0 Plant thionin UBN2_2 PF14227.1 EGG05383.1 - 0.0015 18.1 0.5 0.0065 16.0 0.3 2.1 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type C2 PF00168.25 EGG05384.1 - 4.5e-71 234.7 4.9 7.7e-19 67.3 0.0 6.3 7 0 0 7 7 7 5 C2 domain NT-C2 PF10358.4 EGG05384.1 - 0.0058 16.1 0.0 1.4 8.3 0.0 3.2 3 0 0 3 3 3 2 N-terminal C2 in EEIG1 and EHBP1 proteins Tox-SGS PF15651.1 EGG05385.1 - 0.084 12.6 0.3 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Salivary glad secreted protein domain toxin Gam PF06064.6 EGG05385.1 - 0.63 10.1 4.3 0.79 9.8 0.3 2.4 2 0 0 2 2 2 0 Host-nuclease inhibitor protein Gam R3H-assoc PF13902.1 EGG05385.1 - 2.8 7.9 5.9 0.62 10.0 0.2 2.5 3 0 0 3 3 3 0 R3H-associated N-terminal domain Mg_trans_NIPA PF05653.9 EGG05386.1 - 3.4e-68 229.8 15.8 1.3e-65 221.3 8.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EGG05386.1 - 0.0012 18.8 5.5 0.0012 18.8 3.8 4.0 3 1 0 4 4 4 2 EamA-like transporter family DUF872 PF05915.7 EGG05386.1 - 0.19 11.6 2.2 4.1 7.2 0.0 2.8 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Sod_Cu PF00080.15 EGG05387.1 - 7.2e-18 65.1 0.0 9.3e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pkinase PF00069.20 EGG05391.1 - 1e-62 211.6 0.0 1.8e-62 210.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG05391.1 - 1.4e-34 119.3 0.0 2.4e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG05391.1 - 4.2e-06 25.9 0.0 8.2e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_3 PF14593.1 EGG05391.1 - 0.00048 19.9 2.5 0.15 11.9 0.1 2.8 2 0 0 2 2 2 2 PH domain Kdo PF06293.9 EGG05391.1 - 0.00061 18.9 0.0 0.0014 17.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGG05391.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RPA_C PF08784.6 EGG05394.1 - 0.1 13.0 0.0 0.39 11.1 0.0 2.0 1 1 1 2 2 2 0 Replication protein A C terminal Sigma54_DBD PF04552.8 EGG05396.1 - 0.059 12.8 0.2 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Sigma-54, DNA binding domain zf-CCHC_2 PF13696.1 EGG05400.1 - 0.006 16.0 1.9 0.016 14.7 1.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGG05400.1 - 0.011 15.6 1.3 0.011 15.6 0.9 1.7 2 0 0 2 2 2 0 Zinc knuckle Complex1_LYR PF05347.10 EGG05401.1 - 4.2e-07 29.6 0.2 7.6e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGG05401.1 - 0.0003 20.9 0.2 0.00071 19.7 0.1 1.6 1 1 0 1 1 1 1 Complex1_LYR-like MBOAT_2 PF13813.1 EGG05402.1 - 3.1e-15 56.0 4.8 7.3e-15 54.8 3.3 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF4022 PF13214.1 EGG05402.1 - 0.029 14.4 0.1 0.075 13.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4022) Herpes_LMP1 PF05297.6 EGG05403.1 - 0.21 10.5 3.1 0.11 11.3 1.1 1.3 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ribosom_S12_S23 PF00164.20 EGG05406.1 - 1.2e-46 157.0 2.4 1.6e-46 156.6 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 adh_short PF00106.20 EGG05407.1 - 8.4e-14 51.8 0.1 4.2e-13 49.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG05407.1 - 2.9e-13 50.1 0.0 1.9e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG05407.1 - 1.6e-07 31.1 0.1 3.1e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGG05407.1 - 2.6e-05 24.3 0.1 0.014 15.4 0.1 2.3 2 1 0 2 2 2 2 NADH(P)-binding ApbA PF02558.11 EGG05407.1 - 0.00086 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EGG05407.1 - 0.0048 17.0 0.1 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 EGG05407.1 - 0.074 12.1 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EGG05407.1 - 0.1 12.0 0.1 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GATase_3 PF07685.9 EGG05407.1 - 0.11 12.1 0.0 0.49 9.9 0.0 2.0 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain 3HCDH_N PF02737.13 EGG05407.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.10 EGG05407.1 - 0.14 11.7 0.8 0.34 10.5 0.6 1.8 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Peroxidase_2 PF01328.12 EGG05409.1 - 9.9e-09 34.2 0.3 2.4e-08 33.0 0.2 1.6 1 1 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.12 EGG05410.1 - 9.3e-10 37.6 0.0 2.1e-09 36.5 0.0 1.5 2 0 0 2 2 2 1 Peroxidase, family 2 DUF89 PF01937.14 EGG05411.1 - 2.8e-99 332.2 1.2 3.3e-99 332.0 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF287 PF03384.9 EGG05411.1 - 0.27 11.4 3.1 3.4 7.9 0.4 2.5 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 zf-RING_2 PF13639.1 EGG05415.1 - 1.8e-09 37.2 8.9 1.8e-09 37.2 6.2 1.8 2 0 0 2 2 2 1 Ring finger domain PA PF02225.17 EGG05415.1 - 1.2e-08 34.5 0.0 4.7e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 PA domain zf-RING_5 PF14634.1 EGG05415.1 - 0.00089 18.9 7.5 0.0016 18.1 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGG05415.1 - 0.0057 16.3 6.8 0.014 15.0 4.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TerY-C PF15616.1 EGG05415.1 - 0.017 15.0 2.5 0.026 14.4 1.1 1.7 2 0 0 2 2 2 0 TerY-C metal binding domain zf-C3HC4_2 PF13923.1 EGG05415.1 - 0.021 14.8 7.2 0.075 13.0 5.0 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGG05415.1 - 2.4 8.3 9.3 3.9 7.6 1.0 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger DUF2823 PF11034.3 EGG05416.1 - 7.5e-25 86.8 14.5 8.4e-25 86.6 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) LMP PF04778.7 EGG05416.1 - 0.028 14.1 4.4 0.029 14.1 3.1 1.1 1 0 0 1 1 1 0 LMP repeated region Phe_tRNA-synt_N PF02912.13 EGG05416.1 - 0.062 13.0 0.9 0.14 11.8 0.6 1.8 1 1 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain RP1-2 PF12042.3 EGG05416.1 - 0.07 12.7 0.7 0.081 12.5 0.5 1.2 1 0 0 1 1 1 0 Tubuliform egg casing silk strands structural domain YtxH PF12732.2 EGG05416.1 - 2.7 8.4 6.2 7.2 7.0 4.3 1.7 1 1 0 1 1 1 0 YtxH-like protein Exonuc_VII_L PF02601.10 EGG05417.1 - 0.22 10.6 10.6 0.28 10.3 7.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Borrelia_P83 PF05262.6 EGG05417.1 - 0.86 7.8 21.4 1.2 7.3 14.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2823 PF11034.3 EGG05418.1 - 2e-24 85.4 13.4 2.3e-24 85.2 9.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) DUF883 PF05957.8 EGG05418.1 - 0.36 11.2 3.5 0.97 9.8 2.4 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Rhodanese PF00581.15 EGG05419.1 - 0.014 15.7 0.0 0.051 13.9 0.0 2.0 2 0 0 2 2 2 0 Rhodanese-like domain DSPc PF00782.15 EGG05420.1 - 4.9e-16 58.5 0.2 4.9e-16 58.5 0.1 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGG05420.1 - 0.009 15.3 0.0 0.009 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGG05420.1 - 0.14 12.1 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate Ldh_1_N PF00056.18 EGG05421.1 - 2e-46 157.2 0.2 2.8e-46 156.8 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EGG05421.1 - 1.7e-40 138.5 0.0 2.3e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Semialdhyde_dh PF01118.19 EGG05421.1 - 5.5e-05 23.4 0.1 0.00073 19.8 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EGG05421.1 - 0.00029 19.6 0.0 0.00042 19.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGG05421.1 - 0.021 14.8 0.3 0.059 13.3 0.2 1.7 1 1 0 1 1 1 0 NADH(P)-binding Glyco_hydro_4 PF02056.11 EGG05421.1 - 0.031 13.5 0.1 0.62 9.3 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.14 EGG05421.1 - 0.033 13.2 0.0 0.19 10.8 0.0 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 EGG05421.1 - 0.068 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Saccharop_dh PF03435.13 EGG05421.1 - 0.085 11.8 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase PP28 PF10252.4 EGG05422.1 - 3.3e-23 81.4 14.4 3.3e-23 81.4 10.0 2.7 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 FAM104 PF15434.1 EGG05422.1 - 0.34 11.1 6.0 0.087 13.0 1.7 1.9 2 0 0 2 2 2 0 Family 104 DUF2638 PF10937.3 EGG05422.1 - 0.79 10.7 5.2 0.34 11.9 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2638) BSP_II PF05432.6 EGG05422.1 - 2.6 7.2 25.1 0.82 8.8 15.4 1.5 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) RVT_3 PF13456.1 EGG05424.1 - 2.9e-06 26.9 0.1 6.3e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.19 EGG05424.1 - 0.00012 22.4 0.0 0.00024 21.4 0.0 1.5 1 0 0 1 1 1 1 RNase H OSCP PF00213.13 EGG05425.1 - 0.057 13.2 0.5 0.094 12.5 0.3 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Adaptin_N PF01602.15 EGG05426.1 - 5.3e-144 480.4 5.0 6.5e-144 480.1 3.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGG05426.1 - 1.5e-22 80.3 2.8 4.8e-21 75.4 0.0 3.6 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGG05426.1 - 3.4e-18 65.7 4.5 6e-09 36.0 0.0 5.8 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.17 EGG05426.1 - 9.3e-08 31.5 8.0 0.0091 15.9 0.0 6.7 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.18 EGG05426.1 - 8.5e-05 22.2 1.0 1.5 8.7 0.0 5.2 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EGG05426.1 - 8.8e-05 22.8 10.1 0.15 12.5 0.0 6.9 7 2 2 9 9 9 1 HEAT-like repeat CLASP_N PF12348.3 EGG05426.1 - 0.00039 19.8 0.1 2.1 7.6 0.0 3.3 2 1 1 3 3 3 2 CLASP N terminal Cnd3 PF12719.2 EGG05426.1 - 0.0029 16.6 0.4 0.052 12.5 0.1 2.5 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain WD40 PF00400.27 EGG05427.1 - 2.4e-13 49.4 3.1 8.5e-09 34.9 0.0 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat Sec20 PF03908.8 EGG05428.1 - 0.045 13.4 2.3 0.79 9.4 0.4 2.6 2 0 0 2 2 2 0 Sec20 PPP4R2 PF09184.6 EGG05429.1 - 0.0013 18.3 17.4 0.0029 17.2 12.1 1.5 1 0 0 1 1 1 1 PPP4R2 Mpp10 PF04006.7 EGG05429.1 - 0.0099 14.2 28.3 0.016 13.6 19.6 1.2 1 0 0 1 1 1 1 Mpp10 protein CDC45 PF02724.9 EGG05429.1 - 5.8 4.8 18.3 11 3.8 12.7 1.4 1 0 0 1 1 1 0 CDC45-like protein AUX_IAA PF02309.11 EGG05429.1 - 6.4 6.4 14.1 0.36 10.5 0.9 2.3 2 0 0 2 2 2 0 AUX/IAA family SDA1 PF05285.7 EGG05429.1 - 7.1 5.8 33.2 14 4.8 23.0 1.5 1 0 0 1 1 1 0 SDA1 CNH PF00780.17 EGG05431.1 - 4.3e-13 49.3 0.0 7.7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.4 EGG05431.1 - 3.9e-06 26.8 2.7 2.7e-05 24.1 0.5 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EGG05431.1 - 0.0029 17.7 0.1 0.0029 17.7 0.1 2.4 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Adap_comp_sub PF00928.16 EGG05432.1 - 1.2e-17 63.8 0.0 1.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.4 EGG05432.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DGOK PF05035.7 EGG05432.1 - 0.015 14.0 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase Clat_adaptor_s PF01217.15 EGG05432.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain AAA PF00004.24 EGG05433.1 - 4e-56 188.8 0.0 6.8e-45 152.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGG05433.1 - 3.6e-08 33.3 0.0 0.046 13.6 0.0 3.7 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EGG05433.1 - 5.1e-07 29.8 0.6 0.051 13.5 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EGG05433.1 - 6.5e-07 29.1 0.1 0.0027 17.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGG05433.1 - 2.7e-06 28.1 0.4 0.0027 18.5 0.0 3.1 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGG05433.1 - 9.9e-06 24.7 0.2 0.00029 19.9 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGG05433.1 - 1.1e-05 25.5 1.5 0.021 14.9 0.0 4.1 3 2 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EGG05433.1 - 0.00013 21.3 0.7 0.19 11.0 0.1 3.1 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.1 EGG05433.1 - 0.0002 21.6 0.1 0.028 14.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EGG05433.1 - 0.00025 20.9 0.0 0.008 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EGG05433.1 - 0.00033 19.5 0.2 0.0019 16.9 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus Sigma54_activat PF00158.21 EGG05433.1 - 0.00069 19.1 0.0 1.3 8.4 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EGG05433.1 - 0.00082 18.8 0.0 0.0031 16.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 EGG05433.1 - 0.0015 18.2 0.1 0.0063 16.2 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain UPF0079 PF02367.12 EGG05433.1 - 0.0016 18.0 0.1 0.25 10.9 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EGG05433.1 - 0.0018 18.4 0.0 0.13 12.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Cytidylate_kin2 PF13189.1 EGG05433.1 - 0.002 18.0 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family Zeta_toxin PF06414.7 EGG05433.1 - 0.0025 16.9 0.1 0.098 11.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.6 EGG05433.1 - 0.0041 16.7 0.0 0.065 12.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EGG05433.1 - 0.0074 15.4 0.2 0.024 13.7 0.0 1.8 2 0 0 2 2 2 1 KaiC Mg_chelatase PF01078.16 EGG05433.1 - 0.013 14.7 0.4 0.037 13.1 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EGG05433.1 - 0.016 14.8 0.2 0.36 10.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain PhoH PF02562.11 EGG05433.1 - 0.024 13.8 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EGG05433.1 - 0.027 13.3 0.0 0.058 12.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.1 EGG05433.1 - 0.039 13.8 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EGG05433.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EGG05433.1 - 0.093 12.7 0.0 0.64 10.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 EGG05433.1 - 0.094 12.3 1.5 20 4.8 0.0 3.4 3 1 0 3 3 3 0 NACHT domain ATP-synt_ab PF00006.20 EGG05433.1 - 0.11 11.9 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Na_Ca_ex PF01699.19 EGG05435.1 - 1.3e-45 154.4 26.4 7.8e-24 83.8 8.0 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.7 EGG05435.1 - 0.0046 16.8 0.5 0.056 13.3 0.2 2.7 3 0 0 3 3 3 1 Eukaryotic protein of unknown function (DUF872) DUF952 PF06108.7 EGG05435.1 - 0.054 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF952) Alpha_kinase PF02816.13 EGG05438.1 - 0.056 13.1 0.0 0.08 12.6 0.0 1.4 1 1 0 1 1 1 0 Alpha-kinase family DDE_3 PF13358.1 EGG05439.1 - 0.022 14.5 0.1 0.038 13.7 0.1 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease LMBR1 PF04791.11 EGG05442.1 - 2.9 6.3 5.2 3.9 5.9 3.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Rhodanese PF00581.15 EGG05444.1 - 2.4e-08 34.2 0.0 3.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF4417 PF14386.1 EGG05445.1 - 0.075 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4417) Ribosomal_L28e PF01778.12 EGG05446.1 - 2.9e-21 76.0 0.0 3.4e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family RhoGEF PF00621.15 EGG05447.1 - 1.7e-36 125.8 0.1 2.7e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 EGG05447.1 - 9.4e-33 112.8 0.1 1.7e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 EGG05447.1 - 1.5e-12 46.9 0.0 3.1e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.6 EGG05447.1 - 1.1e-08 34.9 0.1 2.4e-05 24.2 0.0 2.9 2 1 0 2 2 2 1 CDC24 Calponin PH PF00169.24 EGG05447.1 - 0.008 16.3 0.4 0.023 14.8 0.1 1.9 2 0 0 2 2 2 1 PH domain SAM_PNT PF02198.11 EGG05448.1 - 0.023 14.4 0.0 0.086 12.6 0.0 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Sec61_beta PF03911.11 EGG05448.1 - 0.049 13.4 0.1 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Sec61beta family Ras PF00071.17 EGG05450.1 - 3.4e-52 176.0 0.0 4.2e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG05450.1 - 2.6e-19 69.8 0.0 4.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG05450.1 - 2e-07 30.4 0.0 3.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGG05450.1 - 5.5e-05 22.6 0.3 0.001 18.5 0.0 2.5 1 1 1 3 3 3 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGG05450.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGG05450.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGG05450.1 - 0.059 12.8 0.0 1.8 8.0 0.0 2.9 3 1 1 4 4 4 0 Ethanolamine utilisation - propanediol utilisation GRAM PF02893.15 EGG05451.1 - 0.00057 19.3 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.3 EGG05451.1 - 0.0051 16.5 0.0 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 WWbp PF10349.4 EGG05451.1 - 0.2 12.5 0.5 0.33 11.8 0.0 1.8 2 1 0 2 2 2 0 WW-domain ligand protein VRP3 PF03536.10 EGG05454.1 - 0.016 14.4 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein zf-Apc11 PF12861.2 EGG05456.1 - 1.6e-39 133.6 5.3 2.1e-39 133.2 3.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGG05456.1 - 2.8e-29 101.0 8.5 3.9e-29 100.5 5.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGG05456.1 - 1.5e-05 24.7 13.7 3.5e-05 23.5 9.5 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGG05456.1 - 0.028 14.0 12.6 0.11 12.1 8.7 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG05456.1 - 0.051 13.6 10.9 0.61 10.1 7.6 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EGG05456.1 - 0.14 11.6 4.2 0.27 10.7 2.9 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 EGG05456.1 - 0.19 11.4 13.1 2 8.1 9.2 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.1 EGG05456.1 - 0.64 10.0 7.1 1.1 9.2 4.9 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 EGG05456.1 - 1 9.4 7.2 2.6 8.1 5.0 1.7 1 1 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 EGG05456.1 - 1.8 8.6 13.0 4.9 7.1 9.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EGG05456.1 - 7 6.7 11.5 37 4.4 8.0 2.2 1 1 0 1 1 1 0 RING-variant domain Mur_ligase_M PF08245.7 EGG05457.1 - 2.3e-08 34.3 0.1 6.5e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EGG05457.1 - 0.0049 16.8 0.0 0.033 14.2 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Lin0512_fam PF09585.5 EGG05459.1 - 0.18 11.3 0.2 9.6 5.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) RR_TM4-6 PF06459.7 EGG05460.1 - 0.033 14.0 2.0 0.036 13.9 1.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EGG05460.1 - 0.13 11.6 6.0 0.14 11.5 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Mpp10 PF04006.7 EGG05460.1 - 1.4 7.2 12.6 1.5 7.0 8.7 1.0 1 0 0 1 1 1 0 Mpp10 protein Daxx PF03344.10 EGG05460.1 - 5.4 5.3 11.1 5.6 5.3 7.7 1.0 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EGG05460.1 - 8.6 4.1 14.9 8.9 4.0 10.3 1.0 1 0 0 1 1 1 0 Nop14-like family Steroid_dh PF02544.11 EGG05461.1 - 1.6e-22 79.9 0.1 3.5e-20 72.2 0.1 2.3 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Hist_deacetyl PF00850.14 EGG05462.1 - 0.1 11.8 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Histone deacetylase domain Hist_deacetyl PF00850.14 EGG05463.1 - 1e-57 195.7 0.0 1.4e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain zf-UBP PF02148.14 EGG05465.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein TruB_C PF09142.6 EGG05465.1 - 0.34 10.5 2.4 0.6 9.8 0.9 2.1 1 1 1 2 2 2 0 tRNA Pseudouridine synthase II, C terminal SF-assemblin PF06705.6 EGG05466.1 - 0.023 13.8 0.6 0.023 13.8 0.4 1.6 2 0 0 2 2 2 0 SF-assemblin/beta giardin Apolipoprotein PF01442.13 EGG05466.1 - 0.11 11.9 1.9 0.25 10.8 0.2 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EGG05466.1 - 0.13 12.6 3.9 0.71 10.3 0.2 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 EGG05466.1 - 0.29 10.9 1.9 0.66 9.8 1.3 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BAR PF03114.13 EGG05468.1 - 1.7e-42 145.5 6.8 2.2e-42 145.1 4.7 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EGG05468.1 - 0.0022 17.5 0.0 0.005 16.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGG05468.1 - 0.0037 16.6 0.0 0.01 15.2 0.0 1.8 1 0 0 1 1 1 1 SH3 domain BAR_2 PF10455.4 EGG05468.1 - 0.007 15.3 8.1 0.022 13.7 5.6 1.8 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Barwin PF00967.12 EGG05470.1 - 0.00069 19.2 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Barwin family Pollen_allerg_1 PF01357.16 EGG05470.1 - 0.0062 16.3 0.1 0.0062 16.3 0.1 1.8 2 0 0 2 2 2 1 Pollen allergen BNR PF02012.15 EGG05470.1 - 0.071 12.9 0.9 0.071 12.9 0.6 2.6 3 0 0 3 3 3 0 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EGG05470.1 - 0.076 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain BAP PF06639.6 EGG05473.1 - 0.65 9.7 2.8 0.34 10.6 0.2 1.8 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) BAP PF06639.6 EGG05474.1 - 0.041 13.5 0.2 0.041 13.5 0.2 1.6 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) TPR_11 PF13414.1 EGG05475.1 - 8e-07 28.6 1.7 0.014 14.9 0.0 2.6 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGG05475.1 - 0.00039 19.8 0.6 0.11 12.1 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGG05475.1 - 0.0004 20.0 0.2 0.12 12.3 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG05475.1 - 0.0011 18.6 0.1 0.64 9.9 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGG05475.1 - 0.11 13.1 2.3 2.3 9.0 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC15 PF15243.1 EGG05475.1 - 1.9 8.5 9.8 1.1 9.4 0.1 2.9 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 15 DAHP_synth_1 PF00793.15 EGG05476.1 - 4.2e-92 307.6 0.0 5.1e-92 307.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DNA_ligase_A_M PF01068.16 EGG05477.1 - 2e-29 102.3 0.5 6.5e-29 100.7 0.1 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGG05477.1 - 2.7e-10 40.3 0.0 6.4e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus mRNA_cap_enzyme PF01331.14 EGG05477.1 - 0.025 14.2 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain Rho_N PF07498.7 EGG05478.1 - 0.027 14.2 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain SAP PF02037.22 EGG05478.1 - 0.14 11.6 0.1 0.35 10.4 0.1 1.7 1 0 0 1 1 1 0 SAP domain Nucleo_P87 PF07267.6 EGG05478.1 - 0.35 9.4 4.1 0.41 9.2 2.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ish1 PF10281.4 EGG05479.1 - 1.1e-89 294.0 58.3 3.8e-12 46.0 0.3 11.3 11 0 0 11 11 11 11 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EGG05479.1 - 3e-10 39.4 5.1 1.2 8.7 0.0 7.5 8 0 0 8 8 8 3 HeH/LEM domain TilS PF09179.6 EGG05479.1 - 3.3e-08 33.4 0.1 0.036 14.0 0.0 6.0 7 0 0 7 7 7 1 TilS substrate binding domain SAP PF02037.22 EGG05479.1 - 1.2e-06 27.8 0.0 16 5.1 0.0 7.3 8 0 0 8 8 8 0 SAP domain Slx4 PF09494.5 EGG05479.1 - 3.6e-05 23.4 4.7 1.7 8.4 0.0 6.2 7 0 0 7 7 7 1 Slx4 endonuclease DUF1470 PF07336.6 EGG05479.1 - 0.00027 21.2 2.0 0.4 10.9 0.1 5.1 5 1 2 7 7 7 1 Protein of unknown function (DUF1470) Senescence PF06911.7 EGG05479.1 - 0.0068 16.1 0.7 0.019 14.6 0.5 1.7 1 0 0 1 1 1 1 Senescence-associated protein DUF3791 PF12668.2 EGG05479.1 - 0.071 12.7 1.5 19 4.9 0.1 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3791) NICE-3 PF07406.6 EGG05479.1 - 0.94 8.9 6.8 51 3.2 0.2 4.6 3 1 1 5 5 5 0 NICE-3 protein SAM_2 PF07647.12 EGG05479.1 - 1.2 8.9 11.9 31 4.5 0.1 6.8 7 0 0 7 7 7 0 SAM domain (Sterile alpha motif) RsbRD_N PF14361.1 EGG05479.1 - 2 8.8 12.5 2.1 8.8 0.1 4.9 5 2 0 6 6 6 0 RsbT co-antagonist protein rsbRD N-terminal domain Sod_Fe_C PF02777.13 EGG05480.1 - 5.5e-35 119.4 0.3 1.1e-34 118.5 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGG05480.1 - 3.2e-32 110.6 4.7 3.2e-32 110.6 3.3 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HTH_24 PF13412.1 EGG05481.1 - 0.092 12.1 0.1 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Mito_carr PF00153.22 EGG05482.1 - 4.5e-68 225.0 3.1 1.3e-22 79.3 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2442 PF10387.4 EGG05483.1 - 0.01 15.8 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) PPR_1 PF12854.2 EGG05483.1 - 0.13 11.7 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 PPR repeat HMG_box PF00505.14 EGG05484.1 - 2e-25 88.8 1.0 2.4e-25 88.5 0.7 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGG05484.1 - 7.7e-18 64.6 0.7 9.2e-18 64.3 0.5 1.1 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 EGG05484.1 - 0.0098 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.8 EGG05484.1 - 0.014 15.6 0.2 0.016 15.4 0.1 1.3 1 1 0 1 1 1 0 YABBY protein Oxysterol_BP PF01237.13 EGG05486.1 - 6.5e-78 261.6 0.1 8.6e-78 261.2 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein SBDS PF01172.13 EGG05486.1 - 0.0022 17.7 0.8 0.0039 16.9 0.6 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Glyco_hydro_18 PF00704.23 EGG05487.1 - 3.3e-49 168.1 0.0 3.8e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3902 PF13042.1 EGG05489.1 - 0.0089 15.3 0.1 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3902) MFS_2 PF13347.1 EGG05492.1 - 2.1e-06 26.4 17.0 1.9e-05 23.2 11.8 2.3 1 1 0 1 1 1 1 MFS/sugar transport protein ATP_bind_4 PF01902.12 EGG05493.1 - 1.1e-42 145.9 0.0 2.7e-34 118.4 0.0 2.0 1 1 1 2 2 2 2 ATP-binding region Spo12 PF05032.7 EGG05494.1 - 1.3 8.7 3.7 2.2 7.9 2.5 1.3 1 0 0 1 1 1 0 Spo12 family Ribosomal_S27e PF01667.12 EGG05495.1 - 6.8e-31 105.5 4.7 8.6e-31 105.2 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EGG05495.1 - 0.003 17.3 1.6 0.0036 17.1 1.1 1.2 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 EGG05495.1 - 0.3 10.4 2.7 0.44 9.9 1.9 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Sec10 PF07393.6 EGG05496.1 - 3.9e-213 709.6 0.0 4.7e-213 709.3 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 SSDP PF04503.8 EGG05497.1 - 0.38 10.4 15.6 0.42 10.3 10.8 1.1 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP P16-Arc PF04699.9 EGG05498.1 - 1.5e-42 145.1 0.0 1.7e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Pkinase PF00069.20 EGG05499.1 - 2e-70 236.9 0.0 2.4e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG05499.1 - 3.9e-31 108.0 0.0 5.3e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGG05499.1 - 7.4e-05 21.9 0.0 0.00024 20.2 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGG05499.1 - 0.00039 20.2 0.0 0.00091 19.0 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGG05499.1 - 0.0098 14.8 0.0 0.026 13.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGG05499.1 - 0.037 13.3 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Alpha_kinase PF02816.13 EGG05502.1 - 7.6e-09 35.4 0.0 7.6e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family CFEM PF05730.6 EGG05503.1 - 1e-11 44.4 9.5 1.6e-11 43.8 6.6 1.3 1 0 0 1 1 1 1 CFEM domain ORC6 PF05460.8 EGG05506.1 - 0.0056 15.8 9.5 0.0075 15.4 6.6 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) TSGP1 PF07771.6 EGG05506.1 - 3.3 7.6 8.9 6 6.7 6.2 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 DUF4612 PF15389.1 EGG05508.1 - 0.03 14.9 1.2 0.041 14.4 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) MatK_N PF01824.13 EGG05509.1 - 0.017 14.2 0.1 0.024 13.7 0.1 1.3 1 0 0 1 1 1 0 MatK/TrnK amino terminal region DUF1937 PF09152.5 EGG05509.1 - 0.11 13.0 0.0 0.15 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) Aldedh PF00171.17 EGG05510.1 - 1.8e-68 231.0 0.0 4e-68 229.8 0.0 1.5 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Prp19_bind PF06991.6 EGG05511.1 - 8.6e-22 77.7 8.5 8.6e-22 77.7 5.9 2.3 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain SART-1 PF03343.8 EGG05511.1 - 0.023 13.0 21.7 0.028 12.7 15.0 1.1 1 0 0 1 1 1 0 SART-1 family Macoilin PF09726.4 EGG05511.1 - 0.74 8.0 20.3 0.99 7.6 14.1 1.2 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 EGG05511.1 - 3.4 5.6 13.6 3.8 5.4 9.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LAP1C PF05609.7 EGG05511.1 - 5.4 5.5 18.4 7.2 5.1 12.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Adap_comp_sub PF00928.16 EGG05512.1 - 1.2e-24 86.8 0.0 1.3e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family IlvN PF07991.7 EGG05513.1 - 1.1e-46 158.2 0.0 2.6e-46 157.0 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EGG05513.1 - 3.9e-42 143.6 0.0 6.4e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EGG05513.1 - 0.028 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CotJA PF11007.3 EGG05513.1 - 0.044 13.4 0.1 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Spore coat associated protein JA (CotJA) ACC_central PF08326.7 EGG05514.1 - 1.2e-220 734.4 0.0 1.5e-220 734.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EGG05514.1 - 2.7e-165 550.4 0.0 3.7e-165 550.0 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EGG05514.1 - 2.6e-51 173.8 0.1 5e-51 172.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EGG05514.1 - 4.7e-25 87.8 0.1 1.1e-24 86.6 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGG05514.1 - 2.1e-22 79.1 0.0 1e-20 73.6 0.0 2.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EGG05514.1 - 2.2e-14 52.8 0.1 5.2e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EGG05514.1 - 2e-12 47.2 0.0 5.5e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGG05514.1 - 7.8e-05 22.1 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EGG05514.1 - 0.00034 20.5 0.0 0.0014 18.4 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EGG05514.1 - 0.0054 16.3 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like MutS_V PF00488.16 EGG05517.1 - 6.6e-54 182.7 0.1 2.9e-47 161.0 0.1 2.2 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.13 EGG05517.1 - 4.2e-29 101.8 0.4 6.9e-29 101.0 0.3 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EGG05517.1 - 2.5e-07 30.7 0.0 6.9e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV G-alpha PF00503.15 EGG05517.1 - 0.0081 14.8 1.2 0.012 14.2 0.1 1.7 2 0 0 2 2 2 1 G-protein alpha subunit DAP3 PF10236.4 EGG05517.1 - 0.035 13.0 0.0 0.067 12.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Amidohydro_3 PF07969.6 EGG05517.1 - 0.045 12.9 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase family Glucan_synthase PF02364.10 EGG05518.1 - 3.2e-110 369.3 16.5 3.6e-53 180.6 0.7 3.9 1 1 3 4 4 4 4 1,3-beta-glucan synthase component Syntaxin-18_N PF10496.4 EGG05518.1 - 0.036 13.9 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus PRAI PF00697.17 EGG05518.1 - 0.16 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF996 PF06195.8 EGG05519.1 - 0.63 10.0 5.5 2.7 7.9 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF996) Zn_clus PF00172.13 EGG05521.1 - 0.22 11.4 7.6 3.1 7.7 1.5 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sad1_UNC PF07738.8 EGG05526.1 - 1.3e-26 93.0 0.0 1.8e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Fra10Ac1 PF09725.4 EGG05527.1 - 3.2e-12 46.5 0.2 3.9e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Fra10Ac1 PF09725.4 EGG05528.1 - 2.2e-15 56.7 0.0 3.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 DUF1777 PF08648.7 EGG05528.1 - 0.68 9.6 19.4 0.95 9.1 13.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) NPR3 PF03666.8 EGG05528.1 - 3.2 6.1 12.2 0.79 8.1 0.0 2.1 1 1 1 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Caleosin PF05042.8 EGG05530.1 - 2.7e-07 30.3 0.1 7e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Caleosin related protein Excalibur PF05901.6 EGG05530.1 - 0.037 14.3 4.7 0.58 10.5 0.4 3.4 3 0 0 3 3 3 0 Excalibur calcium-binding domain PIF1 PF05970.9 EGG05531.1 - 1.4e-24 86.7 0.7 1.8e-24 86.3 0.5 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EGG05531.1 - 1e-09 38.3 0.2 1.9e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGG05531.1 - 6.4e-07 29.0 0.7 1.3e-06 27.9 0.5 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EGG05531.1 - 2.4e-05 24.4 0.1 6.4e-05 23.1 0.0 1.7 1 1 1 2 2 2 1 AAA domain PhoH PF02562.11 EGG05531.1 - 0.00017 20.9 0.4 0.00027 20.2 0.3 1.2 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 EGG05531.1 - 0.00027 20.0 1.0 0.0008 18.4 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 EGG05531.1 - 0.00039 19.6 0.2 0.00057 19.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGG05531.1 - 0.00061 19.8 0.1 0.001 19.0 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EGG05531.1 - 0.0031 17.1 0.0 0.0052 16.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DEAD PF00270.24 EGG05531.1 - 0.0038 16.7 0.3 0.43 10.0 0.1 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase ABC_tran PF00005.22 EGG05531.1 - 0.0055 17.0 0.2 0.033 14.4 0.0 2.3 3 0 0 3 3 3 1 ABC transporter AAA_25 PF13481.1 EGG05531.1 - 0.012 15.0 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGG05531.1 - 0.026 14.7 0.0 0.069 13.3 0.0 1.9 1 1 0 1 1 1 0 RNA helicase DAP3 PF10236.4 EGG05531.1 - 0.028 13.3 0.1 0.043 12.7 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 EGG05531.1 - 0.038 12.8 0.1 0.047 12.5 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 EGG05531.1 - 0.038 13.5 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EGG05531.1 - 0.067 12.9 0.1 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 EGG05531.1 - 0.072 11.6 0.1 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain UvrD-helicase PF00580.16 EGG05531.1 - 0.079 12.2 0.4 0.15 11.3 0.3 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA PF00004.24 EGG05531.1 - 0.079 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EGG05531.1 - 0.083 12.6 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EGG05531.1 - 0.094 12.1 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 EGG05531.1 - 0.13 11.6 0.4 11 5.3 0.0 2.3 1 1 1 2 2 2 0 IstB-like ATP binding protein Ndc1_Nup PF09531.5 EGG05531.1 - 0.24 9.8 5.3 0.42 8.9 3.7 1.5 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HSP90 PF00183.13 EGG05533.1 - 0.057 11.8 0.0 0.061 11.7 0.0 1.0 1 0 0 1 1 1 0 Hsp90 protein zf-CCCH PF00642.19 EGG05535.1 - 0.00017 21.2 6.2 0.011 15.4 0.3 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Menin PF05053.8 EGG05535.1 - 6 4.9 10.4 0.22 9.6 2.8 1.8 2 0 0 2 2 2 0 Menin UQ_con PF00179.21 EGG05537.1 - 5.9e-17 61.3 0.0 6.3e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGG05537.1 - 0.058 13.2 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain M_domain PF12938.2 EGG05538.1 - 0.37 10.5 2.2 0.51 10.1 1.5 1.4 1 1 0 1 1 1 0 M domain of GW182 C_GCAxxG_C_C PF09719.5 EGG05539.1 - 0.25 11.1 2.8 0.42 10.4 1.9 1.3 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Peptidase_S10 PF00450.17 EGG05541.1 - 1.9e-110 369.8 0.3 2.4e-110 369.5 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase 3Beta_HSD PF01073.14 EGG05542.1 - 1.4e-67 227.3 0.0 1.8e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGG05542.1 - 8.5e-35 120.2 0.0 1.1e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGG05542.1 - 2.6e-14 52.7 0.0 3.1e-13 49.2 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EGG05542.1 - 9.7e-10 37.7 0.0 1.7e-09 36.9 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGG05542.1 - 1.3e-09 38.3 0.0 4.1e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGG05542.1 - 2.7e-09 36.3 0.0 8.8e-09 34.6 0.0 1.8 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein CP12 PF02672.10 EGG05544.1 - 1.2 9.6 6.0 5 7.6 2.4 2.7 1 1 1 2 2 2 0 CP12 domain Smoothelin PF12510.3 EGG05544.1 - 8.4 6.3 10.7 23 4.9 7.4 1.8 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein DYW_deaminase PF14432.1 EGG05545.1 - 0.016 15.2 0.1 0.051 13.5 0.0 1.9 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases R3H PF01424.17 EGG05547.1 - 4.1e-07 29.5 0.0 7.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EGG05547.1 - 0.0035 17.2 24.6 0.0054 16.6 6.3 14.6 17 2 0 17 17 17 7 NF-X1 type zinc finger TPR_11 PF13414.1 EGG05548.1 - 1.2e-30 104.8 8.5 1.6e-08 34.0 0.0 7.9 6 2 2 8 8 8 5 TPR repeat TPR_1 PF00515.23 EGG05548.1 - 5.9e-26 88.9 5.5 0.00046 19.6 0.0 9.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 EGG05548.1 - 2.3e-25 86.4 6.5 0.0002 21.0 0.0 10.3 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGG05548.1 - 1.1e-17 62.4 3.8 0.001 18.6 0.0 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGG05548.1 - 1.2e-16 59.0 1.5 0.021 14.5 0.0 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGG05548.1 - 4.7e-16 58.9 0.1 0.002 18.7 0.0 5.8 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGG05548.1 - 5e-16 58.4 15.1 7.3e-06 25.8 0.2 8.4 7 2 3 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGG05548.1 - 1e-14 53.6 0.1 1.4 9.7 0.0 9.4 7 2 3 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGG05548.1 - 3.5e-14 52.8 1.2 0.0076 16.5 0.0 7.9 8 1 1 9 9 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGG05548.1 - 3e-10 39.4 7.2 0.45 10.8 0.0 8.3 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGG05548.1 - 9.4e-08 32.0 1.5 1 9.9 0.0 7.3 8 0 0 8 8 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EGG05548.1 - 5.4e-07 29.6 4.2 0.00016 21.7 0.2 4.4 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EGG05548.1 - 0.00036 20.3 9.5 4.2 7.4 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGG05548.1 - 0.00051 19.8 0.6 2.5 8.0 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 EGG05548.1 - 0.0046 16.1 0.4 0.19 10.8 0.1 2.9 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_20 PF14561.1 EGG05548.1 - 0.0086 16.1 0.2 12 6.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 EGG05548.1 - 0.077 11.7 0.1 0.19 10.4 0.0 1.6 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Clathrin PF00637.15 EGG05548.1 - 0.19 11.3 3.2 2 8.0 0.1 3.5 3 1 0 3 3 3 0 Region in Clathrin and VPS TPR_3 PF07720.7 EGG05548.1 - 8.6 6.2 7.4 7.4 6.4 0.8 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.22 EGG05549.1 - 7.9e-33 112.0 3.3 7.4e-17 60.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M28 PF04389.12 EGG05550.1 - 1e-12 48.1 0.0 2.1e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 DUF3290 PF11694.3 EGG05550.1 - 0.034 13.8 1.3 0.062 13.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) UCR_TM PF02921.9 EGG05551.1 - 1.2e-19 70.3 2.0 1.8e-19 69.7 1.4 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EGG05551.1 - 9e-18 63.6 0.0 1.3e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain SNF2_N PF00176.18 EGG05553.1 - 9.2e-14 50.9 0.2 1.4e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.18 EGG05554.1 - 1.6e-45 155.1 0.0 2.6e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGG05554.1 - 3.5e-13 49.2 0.0 7.4e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGG05554.1 - 0.0022 17.5 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Clathrin PF00637.15 EGG05555.1 - 5.7e-12 45.4 6.6 1.5e-11 44.0 0.3 3.5 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.3 EGG05555.1 - 0.00069 19.4 0.2 0.00069 19.4 0.1 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal Prok-RING_1 PF14446.1 EGG05555.1 - 0.0029 17.2 2.3 0.006 16.2 1.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 RNA_GG_bind PF10258.4 EGG05555.1 - 0.01 15.5 0.7 0.037 13.7 0.5 1.9 1 0 0 1 1 1 0 PHAX RNA-binding domain zf-RING_5 PF14634.1 EGG05555.1 - 0.027 14.2 6.7 0.061 13.0 4.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EGG05555.1 - 0.067 13.0 6.8 0.17 11.7 4.7 1.7 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.2 EGG05555.1 - 0.081 13.0 3.0 0.25 11.4 2.1 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGG05555.1 - 3.4 7.7 6.8 7.7 6.6 4.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UQ_con PF00179.21 EGG05560.1 - 1.3e-44 151.0 0.0 1.7e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGG05560.1 - 0.00023 21.0 0.0 0.00032 20.5 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EGG05560.1 - 0.0014 18.3 0.2 0.0023 17.6 0.1 1.5 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 EGG05560.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Peptidase_S64 PF08192.6 EGG05562.1 - 4.7 5.4 12.5 8 4.6 8.7 1.4 1 0 0 1 1 1 0 Peptidase family S64 DUF4490 PF14892.1 EGG05563.1 - 0.089 12.4 0.0 0.22 11.1 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4490) LRR_4 PF12799.2 EGG05566.1 - 0.15 11.7 8.8 6 6.5 1.8 4.2 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRRNT PF01462.13 EGG05566.1 - 0.45 10.0 1.5 35 4.0 0.0 3.6 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain DASH_Dad3 PF08656.5 EGG05568.1 - 6.2e-20 70.6 0.7 7.7e-20 70.3 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 NAD_binding_2 PF03446.10 EGG05569.1 - 2.6e-33 115.1 0.2 5e-32 110.9 0.2 2.1 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGG05569.1 - 1.4e-27 96.1 0.0 3.3e-27 94.9 0.0 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Got1 PF04178.7 EGG05571.1 - 2.1e-22 79.4 24.4 2.5e-22 79.2 16.9 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4027 PF13219.1 EGG05571.1 - 1.2 8.6 5.5 0.38 10.2 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4027) CIA30 PF08547.7 EGG05572.1 - 1.1e-23 83.7 0.0 1.5e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) GIT_SHD PF08518.6 EGG05572.1 - 0.0039 16.4 0.1 0.0079 15.5 0.1 1.4 1 0 0 1 1 1 1 Spa2 homology domain (SHD) of GIT zf-CCHC PF00098.18 EGG05573.1 - 0.001 18.8 2.3 0.001 18.8 1.6 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGG05573.1 - 0.045 13.4 1.4 0.1 12.2 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle Cucumo_2B PF03263.8 EGG05573.1 - 0.054 13.7 0.2 0.26 11.5 0.1 2.2 2 0 0 2 2 2 0 Cucumovirus protein 2B ArfGap PF01412.13 EGG05574.1 - 1.9e-34 117.9 0.3 6e-34 116.3 0.2 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Zip PF02535.17 EGG05575.1 - 7.4e-17 61.3 26.0 1.2e-12 47.5 12.5 4.0 1 1 2 3 3 3 2 ZIP Zinc transporter TPR_2 PF07719.12 EGG05577.1 - 0.00052 19.7 0.3 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Fer4_13 PF13370.1 EGG05577.1 - 0.026 14.8 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain TPR_14 PF13428.1 EGG05577.1 - 0.045 14.3 0.1 0.34 11.6 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGG05577.1 - 0.057 13.9 0.0 0.62 10.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGG05577.1 - 0.06 13.0 0.2 0.15 11.6 0.1 1.7 1 1 0 1 1 1 0 TPR repeat HP_OMP PF01856.12 EGG05577.1 - 0.091 12.5 0.1 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Helicobacter outer membrane protein Suf PF05843.9 EGG05577.1 - 0.13 11.9 0.3 0.15 11.7 0.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) COG6 PF06419.6 EGG05578.1 - 0.051 11.7 0.2 0.058 11.5 0.1 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 CAMSAP_CH PF11971.3 EGG05578.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain Pneumovirus_M2 PF06436.6 EGG05578.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) Adeno_PVIII PF01310.13 EGG05579.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 2 0 0 2 2 2 0 Adenovirus hexon associated protein, protein VIII Barwin PF00967.12 EGG05581.1 - 0.055 13.1 2.5 0.21 11.2 0.1 2.3 2 0 0 2 2 2 0 Barwin family SNARE_assoc PF09335.6 EGG05584.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein Cwf_Cwc_15 PF04889.7 EGG05588.1 - 0.017 14.8 6.6 0.025 14.3 4.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Evr1_Alr PF04777.8 EGG05591.1 - 0.016 15.1 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Erv1 / Alr family DUF4044 PF13253.1 EGG05591.1 - 1.3 8.2 6.8 9.8 5.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4044) LPP PF04728.8 EGG05592.1 - 0.0053 16.5 3.0 0.37 10.6 0.4 2.8 1 1 1 2 2 2 1 Lipoprotein leucine-zipper Cep57_CLD PF14073.1 EGG05592.1 - 0.011 15.6 7.7 0.019 14.7 4.9 1.6 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 COG5 PF10392.4 EGG05592.1 - 0.025 14.5 5.7 0.1 12.5 3.9 1.9 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Reo_sigmaC PF04582.7 EGG05592.1 - 0.034 13.3 1.7 0.069 12.3 1.1 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EGG05592.1 - 0.12 12.2 7.5 0.22 11.3 5.2 1.3 1 0 0 1 1 1 0 Tropomyosin like Mnd1 PF03962.10 EGG05592.1 - 0.59 9.7 6.5 0.91 9.1 4.5 1.2 1 0 0 1 1 1 0 Mnd1 family FliT PF05400.8 EGG05592.1 - 1.1 9.7 8.6 0.57 10.6 4.5 1.6 2 0 0 2 2 1 0 Flagellar protein FliT DUF1664 PF07889.7 EGG05592.1 - 1.1 9.0 5.1 2 8.1 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 EGG05592.1 - 1.3 8.5 9.3 0.29 10.7 3.7 1.8 1 1 1 2 2 2 0 IncA protein SlyX PF04102.7 EGG05592.1 - 4.7 7.6 11.0 3 8.2 3.2 2.6 1 1 1 2 2 2 0 SlyX bZIP_2 PF07716.10 EGG05592.1 - 7.3 6.4 8.9 37 4.2 1.9 3.2 2 1 1 3 3 3 0 Basic region leucine zipper Tropomyosin PF00261.15 EGG05593.1 - 1.5e-07 30.7 6.9 2.1e-07 30.3 4.8 1.1 1 0 0 1 1 1 1 Tropomyosin PspA_IM30 PF04012.7 EGG05593.1 - 7.7e-06 25.4 6.9 0.00024 20.5 0.3 2.0 1 1 1 2 2 2 2 PspA/IM30 family FlaC_arch PF05377.6 EGG05593.1 - 0.0012 18.7 1.6 0.011 15.6 0.0 2.6 2 1 0 2 2 2 1 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 EGG05593.1 - 0.0036 17.1 10.6 0.15 11.8 4.1 2.1 1 1 1 2 2 2 2 Tropomyosin like BLOC1_2 PF10046.4 EGG05593.1 - 0.0098 16.0 5.5 0.012 15.7 2.4 1.9 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.16 EGG05593.1 - 0.02 14.4 6.8 0.023 14.2 4.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein SlyX PF04102.7 EGG05593.1 - 0.025 14.9 5.9 0.034 14.5 0.5 2.2 1 1 1 2 2 2 0 SlyX DDE_Tnp_IS66 PF03050.9 EGG05593.1 - 0.027 13.6 2.9 0.034 13.3 2.0 1.1 1 0 0 1 1 1 0 Transposase IS66 family ORF6C PF10552.4 EGG05593.1 - 0.042 13.5 4.0 0.15 11.8 0.2 2.2 1 1 0 2 2 2 0 ORF6C domain DUF342 PF03961.8 EGG05593.1 - 0.044 12.2 4.3 0.051 12.0 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc7 PF08317.6 EGG05593.1 - 0.14 10.7 7.1 0.17 10.5 4.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 EGG05593.1 - 0.17 10.8 6.7 0.18 10.7 4.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 EGG05593.1 - 0.2 11.3 6.6 0.7 9.6 4.5 1.9 1 1 0 1 1 1 0 Laminin Domain II CDC37_N PF03234.9 EGG05593.1 - 0.21 11.9 10.0 0.038 14.3 1.7 2.1 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DivIVA PF05103.8 EGG05593.1 - 0.23 11.5 8.0 0.35 10.9 5.6 1.4 1 0 0 1 1 1 0 DivIVA protein CHD5 PF04420.9 EGG05593.1 - 0.23 11.0 4.4 0.24 11.0 2.3 1.6 1 1 0 1 1 1 0 CHD5-like protein ADIP PF11559.3 EGG05593.1 - 0.31 10.9 13.3 2 8.3 2.2 2.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Tweety PF04906.8 EGG05593.1 - 0.32 9.3 1.4 0.43 8.9 1.0 1.2 1 0 0 1 1 1 0 Tweety Uds1 PF15456.1 EGG05593.1 - 0.34 10.9 8.7 1.2 9.0 5.7 2.1 1 1 0 1 1 1 0 Up-regulated During Septation GrpE PF01025.14 EGG05593.1 - 0.41 10.1 9.1 1.6 8.2 1.2 1.9 1 1 1 2 2 2 0 GrpE DUF4200 PF13863.1 EGG05593.1 - 0.42 10.5 10.3 1 9.2 7.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) AATF-Che1 PF13339.1 EGG05593.1 - 0.5 10.5 6.2 0.54 10.4 3.2 1.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Streptin-Immun PF11083.3 EGG05593.1 - 0.76 9.7 5.2 1.7 8.6 2.7 2.1 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein XhlA PF10779.4 EGG05593.1 - 2.2 8.2 7.8 5.9 6.8 1.8 2.3 1 1 1 2 2 2 0 Haemolysin XhlA HemX PF04375.9 EGG05593.1 - 2.3 6.7 8.2 7 5.1 5.7 1.7 1 1 0 1 1 1 0 HemX DUF2802 PF10975.3 EGG05593.1 - 2.9 7.7 6.0 13 5.5 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) Fib_alpha PF08702.5 EGG05593.1 - 3.4 7.7 8.1 12 6.0 5.5 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.4 EGG05593.1 - 4.3 7.1 10.6 5.3 6.8 1.8 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain DUF724 PF05266.9 EGG05593.1 - 4.9 6.7 11.4 11 5.6 7.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF848 PF05852.6 EGG05593.1 - 6.3 6.6 10.2 40 4.0 5.4 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) IncA PF04156.9 EGG05593.1 - 7 6.1 11.0 23 4.4 7.7 1.8 1 1 0 1 1 1 0 IncA protein TMPIT PF07851.8 EGG05593.1 - 7.5 5.5 6.8 8.9 5.2 4.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein TPD52 PF04201.10 EGG05595.1 - 0.0085 15.8 7.7 0.03 14.0 5.3 2.0 1 1 0 1 1 1 1 Tumour protein D52 family Reo_sigmaC PF04582.7 EGG05595.1 - 0.037 13.2 3.3 0.07 12.2 2.3 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EGG05595.1 - 0.15 11.8 5.1 0.54 10.0 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Vps51 PF08700.6 EGG05595.1 - 0.61 9.9 8.0 0.14 12.0 2.3 2.4 2 0 0 2 2 2 0 Vps51/Vps67 Muted PF14942.1 EGG05595.1 - 1.5 8.6 11.2 0.45 10.3 4.8 2.2 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Fib_alpha PF08702.5 EGG05595.1 - 2.4 8.2 15.9 0.071 13.2 5.4 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Prominin PF05478.6 EGG05595.1 - 3 5.2 9.3 4.6 4.6 6.4 1.2 1 0 0 1 1 1 0 Prominin DUF948 PF06103.6 EGG05595.1 - 3.4 7.5 6.1 18 5.2 3.7 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2730 PF10805.3 EGG05595.1 - 9.4 6.0 9.6 5.9 6.6 1.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Desmo_N PF06771.6 EGG05596.1 - 0.03 14.2 1.3 0.086 12.7 0.1 2.1 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus DUF956 PF06115.6 EGG05596.1 - 0.046 13.3 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF956) Cep57_MT_bd PF06657.8 EGG05596.1 - 0.084 12.8 2.7 0.15 11.9 1.9 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF334 PF03904.8 EGG05596.1 - 0.095 12.0 1.2 0.24 10.6 0.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF334) DUF3308 PF11751.3 EGG05598.1 - 0.00067 19.0 0.8 0.00076 18.8 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3308) OMP_b-brl_2 PF13568.1 EGG05598.1 - 0.029 14.1 1.8 0.043 13.6 0.9 1.7 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain RGCC PF15151.1 EGG05598.1 - 0.11 12.9 0.5 0.19 12.1 0.4 1.4 1 0 0 1 1 1 0 Response gene to complement 32 protein family BPL_LplA_LipB PF03099.14 EGG05599.1 - 0.076 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Serendipity_A PF05482.7 EGG05600.1 - 0.086 11.2 0.1 0.1 11.0 0.1 1.0 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) DUF3556 PF12077.3 EGG05602.1 - 0.15 10.0 0.0 0.25 9.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) GFA PF04828.9 EGG05602.1 - 0.42 10.5 4.0 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Fib_alpha PF08702.5 EGG05603.1 - 0.13 12.3 0.4 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Alpha-mann_mid PF09261.6 EGG05603.1 - 0.2 11.9 0.9 5.3 7.3 0.2 2.6 3 0 0 3 3 3 0 Alpha mannosidase, middle domain BTG PF07742.7 EGG05604.1 - 0.035 13.5 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 BTG family MCM PF00493.18 EGG05607.1 - 1.7e-133 444.4 0.0 2.9e-133 443.7 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGG05607.1 - 2.3e-19 70.0 0.0 9.5e-19 68.0 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 EGG05607.1 - 1.4e-08 34.5 0.0 4.6e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGG05607.1 - 1.4e-07 30.9 0.0 4.8e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGG05607.1 - 0.00026 20.5 0.0 0.002 17.7 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGG05607.1 - 0.00089 18.7 0.1 0.98 8.8 0.0 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_32 PF13654.1 EGG05607.1 - 0.083 11.5 0.8 0.14 10.7 0.2 1.6 2 0 0 2 2 2 0 AAA domain Zn-ribbon_8 PF09723.5 EGG05607.1 - 0.17 11.8 0.7 0.4 10.6 0.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain AAA_16 PF13191.1 EGG05607.1 - 1.1 9.1 4.8 6.1 6.7 0.0 3.8 4 1 1 5 5 5 0 AAA ATPase domain ORMDL PF04061.9 EGG05608.1 - 6.8e-49 164.9 2.0 8.6e-49 164.5 1.4 1.1 1 0 0 1 1 1 1 ORMDL family zf-AN1 PF01428.11 EGG05609.1 - 1.7e-15 56.6 26.2 3.5e-10 39.5 3.6 3.1 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EGG05609.1 - 0.2 11.8 14.0 0.15 12.3 2.4 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain PSD1 PF07587.6 EGG05611.1 - 0.019 14.3 0.1 0.055 12.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1553) Drf_GBD PF06371.8 EGG05615.1 - 8e-12 44.8 1.6 8.8e-11 41.5 0.1 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EGG05615.1 - 4.2e-06 26.3 2.7 5.9e-06 25.8 0.6 2.2 2 1 0 2 2 2 1 Diaphanous FH3 Domain FH2 PF02181.18 EGG05616.1 - 1.3e-41 142.7 0.4 2e-32 112.4 0.0 2.4 2 1 0 2 2 2 2 Formin Homology 2 Domain AKNA PF12443.3 EGG05616.1 - 0.019 14.9 0.2 2.9 7.9 0.0 3.3 3 0 0 3 3 3 0 AT-hook-containing transcription factor B_lectin PF01453.19 EGG05617.1 - 0.016 15.0 0.0 0.039 13.8 0.0 1.6 1 1 0 1 1 1 0 D-mannose binding lectin zf-ISL3 PF14690.1 EGG05618.1 - 0.0022 18.0 0.7 0.1 12.6 0.0 2.2 2 0 0 2 2 2 2 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-NADH-PPase PF09297.6 EGG05618.1 - 0.0055 16.1 2.7 2 7.9 0.5 2.4 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain TFIIF_alpha PF05793.7 EGG05621.1 - 1.8 6.8 33.0 3 6.0 22.9 1.5 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) POT1 PF02765.12 EGG05623.1 - 0.0039 17.1 0.0 0.0043 16.9 0.0 1.1 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 EGG05623.1 - 0.065 13.0 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF2670 PF10875.3 EGG05625.1 - 0.13 12.3 0.1 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) DUF3605 PF12239.3 EGG05628.1 - 1.1e-08 35.0 0.6 8.7e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) MORN_2 PF07661.8 EGG05628.1 - 0.06 13.3 0.6 7.5 6.9 0.1 2.5 2 0 0 2 2 2 0 MORN repeat variant IF-2B PF01008.12 EGG05629.1 - 5.2e-71 238.9 0.0 6.1e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PSD1 PF07587.6 EGG05630.1 - 0.025 13.9 0.2 0.035 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) Pox_Ag35 PF03286.9 EGG05630.1 - 6.6 6.1 17.2 0.7 9.3 6.3 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Ferric_reduct PF01794.14 EGG05631.1 - 4.1e-16 59.2 8.0 4.1e-16 59.2 5.5 2.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EGG05631.1 - 1.1e-06 28.6 0.1 3.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EGG05631.1 - 0.075 13.6 0.0 0.16 12.5 0.0 1.6 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain CDP-OH_P_transf PF01066.16 EGG05633.1 - 2.8e-10 40.4 1.2 5.1e-10 39.5 0.8 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase F-box-like PF12937.2 EGG05636.1 - 0.062 13.0 1.6 0.17 11.6 0.2 2.4 2 0 0 2 2 2 0 F-box-like Proteasome PF00227.21 EGG05638.1 - 5.7e-59 198.6 0.0 7.8e-59 198.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGG05638.1 - 3e-14 52.0 0.1 5.9e-14 51.0 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3228 PF11539.3 EGG05638.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) Laminin_EGF PF00053.19 EGG05639.1 - 0.95 9.4 8.5 3.4 7.6 0.8 2.6 2 1 0 2 2 2 0 Laminin EGF-like (Domains III and V) zf-C4_ClpX PF06689.8 EGG05639.1 - 4.9 6.7 6.0 7.7 6.1 1.3 2.5 2 1 0 2 2 2 0 ClpX C4-type zinc finger zf-B_box PF00643.19 EGG05640.1 - 1.7 8.6 7.5 0.75 9.7 0.2 3.0 3 0 0 3 3 3 0 B-box zinc finger zf-B_box PF00643.19 EGG05641.1 - 0.029 14.2 0.5 0.029 14.2 0.3 2.9 3 0 0 3 3 3 0 B-box zinc finger Laminin_EGF PF00053.19 EGG05641.1 - 4.2 7.3 7.7 4.3 7.3 0.6 2.4 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) Thioredoxin_4 PF13462.1 EGG05642.1 - 1.5e-06 28.3 0.0 5.4e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin DUF4254 PF14063.1 EGG05642.1 - 0.042 13.4 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) DSBA PF01323.15 EGG05642.1 - 0.11 12.0 2.3 0.35 10.3 0.1 2.4 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Dynactin PF12455.3 EGG05643.1 - 2e-68 230.2 11.0 2e-68 230.2 7.7 3.5 3 1 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 EGG05643.1 - 1.7e-21 75.6 1.0 2.9e-21 74.9 0.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF730 PF05325.6 EGG05643.1 - 0.0063 16.3 0.3 0.0063 16.3 0.2 3.9 5 0 0 5 5 5 1 Protein of unknown function (DUF730) SOR_SNZ PF01680.12 EGG05644.1 - 1.1e-112 374.7 4.8 1.5e-112 374.2 3.3 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EGG05644.1 - 4.3e-11 42.3 4.3 1.4e-07 30.8 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EGG05644.1 - 2.8e-07 29.6 0.6 0.00043 19.2 0.0 2.8 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) NanE PF04131.9 EGG05644.1 - 0.00052 19.0 0.1 0.042 12.8 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 EGG05644.1 - 0.00053 19.3 0.1 0.056 12.6 0.0 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 EGG05644.1 - 0.0018 17.5 0.1 0.0018 17.5 0.1 2.2 2 1 0 2 2 2 1 Nitronate monooxygenase IGPS PF00218.16 EGG05644.1 - 0.0035 16.4 0.1 0.016 14.2 0.0 2.0 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase Trp_syntA PF00290.15 EGG05644.1 - 0.057 11.9 0.0 0.097 11.1 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain HSP70 PF00012.15 EGG05645.1 - 5e-271 899.9 3.3 5.7e-271 899.7 2.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGG05645.1 - 6.3e-15 54.5 0.1 8.8e-14 50.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EGG05645.1 - 0.0051 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EGG05645.1 - 0.0068 16.2 0.4 0.24 11.2 0.3 3.1 1 1 0 1 1 1 1 Cell division protein FtsA Hydantoinase_A PF01968.13 EGG05645.1 - 0.0084 15.2 0.2 0.06 12.4 0.0 2.2 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase Radial_spoke_3 PF06098.6 EGG05645.1 - 0.053 12.5 1.1 0.089 11.7 0.7 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 COMP PF11598.3 EGG05647.1 - 0.14 12.2 0.1 0.46 10.5 0.1 1.9 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Pkinase PF00069.20 EGG05648.1 - 2.2e-25 89.3 0.0 3.7e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG05648.1 - 6e-14 51.7 0.0 3.6e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase OPT PF03169.10 EGG05649.1 - 4.2e-92 309.5 34.7 5.4e-92 309.2 24.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.10 EGG05650.1 - 2.2e-76 257.6 30.6 2.6e-56 191.3 10.9 3.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein DUF3265 PF11665.3 EGG05650.1 - 0.054 13.3 0.5 0.3 10.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3265) Glu_synthase PF01645.12 EGG05651.1 - 6.4e-160 532.0 0.0 1e-159 531.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EGG05651.1 - 2.6e-134 447.5 0.0 3.6e-134 447.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EGG05651.1 - 2.5e-117 391.2 0.0 3.9e-117 390.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EGG05651.1 - 6.9e-69 230.9 3.1 1.2e-68 230.0 2.1 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EGG05651.1 - 1.6e-22 79.2 0.1 1.6e-22 79.2 0.1 2.0 3 0 0 3 3 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EGG05651.1 - 7.5e-17 61.8 0.0 1.9e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGG05651.1 - 1.1e-11 45.1 0.1 7.6e-05 22.8 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGG05651.1 - 3.7e-07 30.0 0.0 1.5e-06 28.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGG05651.1 - 1.7e-06 28.2 0.0 0.0015 18.9 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGG05651.1 - 7e-05 21.8 0.2 0.00063 18.7 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGG05651.1 - 7.2e-05 21.4 0.8 0.00012 20.6 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EGG05651.1 - 0.0014 17.8 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EGG05651.1 - 0.0017 17.3 0.1 0.0065 15.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 EGG05651.1 - 0.0042 17.3 2.7 1.1 9.5 0.0 3.1 3 0 0 3 3 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EGG05651.1 - 0.0087 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGG05651.1 - 0.011 14.8 0.1 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.14 EGG05651.1 - 0.016 14.3 0.3 0.061 12.4 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EGG05651.1 - 0.019 14.0 0.1 0.059 12.4 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EGG05651.1 - 0.034 13.7 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 EGG05651.1 - 0.044 13.6 0.2 9.9 5.9 0.0 2.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FMN_dh PF01070.13 EGG05651.1 - 0.057 12.2 0.9 0.27 10.0 0.6 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NAD_Gly3P_dh_N PF01210.18 EGG05651.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EGG05651.1 - 0.15 11.6 0.1 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.14 EGG05651.1 - 0.71 7.9 0.0 13 3.8 0.0 2.5 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NDUFA12 PF05071.11 EGG05652.1 - 6e-10 39.5 0.5 1.7e-09 38.0 0.3 1.9 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Tau95 PF09734.4 EGG05653.1 - 5.7e-36 124.4 0.3 9.2e-36 123.7 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit CENP-T PF15511.1 EGG05653.1 - 0.025 13.8 24.9 0.04 13.1 17.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T OPT PF03169.10 EGG05654.1 - 1e-59 202.6 32.9 1.9e-56 191.8 22.8 3.4 1 1 0 1 1 1 1 OPT oligopeptide transporter protein CDtoxinA PF03498.9 EGG05654.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family Cyto_heme_lyase PF01265.12 EGG05658.1 - 6e-64 216.1 0.3 9e-64 215.5 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase GAGA PF09237.6 EGG05658.1 - 0.096 12.2 1.0 0.83 9.2 0.2 2.2 2 0 0 2 2 2 0 GAGA factor zf-CHY PF05495.7 EGG05659.1 - 1.9e-14 53.5 13.2 2.5e-14 53.1 9.2 1.1 1 0 0 1 1 1 1 CHY zinc finger Elf1 PF05129.8 EGG05659.1 - 0.016 14.8 5.7 0.25 11.0 4.0 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Cys_rich_KTR PF14205.1 EGG05659.1 - 0.028 13.8 5.6 2.1 7.8 1.2 2.4 1 1 1 2 2 2 0 Cysteine-rich KTR zinc_ribbon_5 PF13719.1 EGG05659.1 - 0.056 13.0 10.2 0.15 11.7 1.7 2.8 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGG05659.1 - 0.069 12.8 10.7 0.14 11.8 1.5 2.9 2 1 0 2 2 2 0 zinc-ribbon domain zf-UDP PF14569.1 EGG05659.1 - 0.079 12.7 4.2 0.13 11.9 2.3 1.8 1 1 1 2 2 2 0 Zinc-binding RING-finger NOB1_Zn_bind PF08772.6 EGG05659.1 - 0.15 11.9 0.4 0.15 11.9 0.3 1.6 2 0 0 2 2 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.1 EGG05659.1 - 0.16 11.4 0.3 0.16 11.4 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 EGG05659.1 - 0.26 11.1 9.8 2.5 7.9 6.8 2.5 1 1 0 1 1 1 0 Double zinc ribbon C1_4 PF07975.7 EGG05659.1 - 0.53 10.3 11.2 0.078 12.9 1.5 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain Tmemb_55A PF09788.4 EGG05659.1 - 0.62 9.1 4.3 0.78 8.8 3.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A HypA PF01155.14 EGG05659.1 - 0.75 9.4 7.5 0.081 12.6 0.6 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 EGG05659.1 - 0.92 9.3 10.3 6.8 6.5 0.1 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Cytochrome_C7 PF14522.1 EGG05659.1 - 1.1 8.9 7.6 2.1 8.0 5.3 1.5 1 1 0 1 1 1 0 Cytochrome c7 Zn-ribbon_8 PF09723.5 EGG05659.1 - 1.6 8.7 12.5 0.47 10.4 1.6 2.6 2 1 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.1 EGG05659.1 - 1.8 9.0 7.5 20 5.6 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-RING_3 PF14369.1 EGG05659.1 - 2.4 8.2 12.2 0.88 9.6 2.4 2.9 2 1 1 3 3 3 0 zinc-finger Sporozoite_P67 PF05642.6 EGG05660.1 - 0.024 12.5 0.6 0.037 11.9 0.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen E1_dh PF00676.15 EGG05661.1 - 2.5e-112 374.4 0.0 3.3e-112 374.0 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EGG05661.1 - 0.0055 15.6 0.0 0.0082 15.1 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.16 EGG05661.1 - 0.016 14.0 0.0 0.03 13.1 0.0 1.4 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain LRR_8 PF13855.1 EGG05662.1 - 0.026 14.2 0.1 0.026 14.2 0.1 4.5 3 1 1 4 4 4 0 Leucine rich repeat LRR_5 PF13306.1 EGG05662.1 - 0.043 13.5 7.0 1.9 8.1 0.2 2.6 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) Mgm101p PF06420.7 EGG05663.1 - 1.4e-79 265.3 0.0 1.8e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Cupin_8 PF13621.1 EGG05665.1 - 4.6e-16 59.0 0.2 1.2e-12 47.8 0.0 2.3 2 0 0 2 2 2 2 Cupin-like domain JmjC PF02373.17 EGG05665.1 - 0.00027 21.1 0.5 0.001 19.2 0.2 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase B12D PF06522.6 EGG05666.1 - 5.2e-19 67.7 0.1 5.9e-19 67.5 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Chromo PF00385.19 EGG05675.1 - 0.00066 19.2 1.4 0.00066 19.2 1.0 2.9 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Nit_Regul_Hom PF10126.4 EGG05675.1 - 0.061 13.0 1.1 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII DUF726 PF05277.7 EGG05676.1 - 7.1e-73 245.4 0.1 1e-72 244.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EGG05676.1 - 0.00097 18.9 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG05676.1 - 0.0021 17.9 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EGG05676.1 - 0.0028 17.0 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain LCAT PF02450.10 EGG05676.1 - 0.0053 15.7 0.1 0.011 14.6 0.0 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 EGG05676.1 - 0.0075 15.6 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) MRP-S25 PF13741.1 EGG05677.1 - 6.5e-16 58.5 0.1 7.6e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 LEDGF PF11467.3 EGG05680.1 - 0.023 14.3 0.1 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) Carbpep_Y_N PF05388.6 EGG05681.1 - 0.056 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide YdfZ PF14001.1 EGG05682.1 - 0.095 12.9 0.0 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 YdfZ protein DnaJ PF00226.26 EGG05686.1 - 1.5e-10 40.6 0.0 8.6e-10 38.2 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_12 PF13424.1 EGG05686.1 - 0.07 13.0 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGG05686.1 - 0.38 11.1 2.2 0.68 10.3 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat DBB PF14545.1 EGG05690.1 - 0.0089 15.5 5.4 0.012 15.0 3.7 1.2 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, Porin_3 PF01459.17 EGG05690.1 - 0.026 13.8 0.8 0.042 13.1 0.6 1.4 1 1 0 1 1 1 0 Eukaryotic porin LEA_2 PF03168.8 EGG05690.1 - 0.038 14.3 4.2 0.17 12.2 2.2 2.2 1 1 1 2 2 2 0 Late embryogenesis abundant protein DUF4289 PF14121.1 EGG05690.1 - 0.068 11.5 0.1 0.066 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4289) DUF1943 PF09172.6 EGG05690.1 - 0.11 11.2 3.1 0.19 10.5 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) AMP-binding_C_2 PF14535.1 EGG05690.1 - 0.57 10.2 7.4 3.8 7.6 5.1 2.2 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Glyco_hydro_2 PF00703.16 EGG05690.1 - 0.97 9.9 5.7 15 6.0 4.0 2.2 1 1 0 1 1 1 0 Glycosyl hydrolases family 2 Bactofilin PF04519.8 EGG05690.1 - 1 9.4 5.2 0.64 10.0 2.0 1.8 2 1 0 2 2 2 0 Polymer-forming cytoskeletal DUF3656 PF12392.3 EGG05690.1 - 1.7 8.7 6.0 13 5.8 4.1 2.2 1 1 0 1 1 1 0 Collagenase DUF4131 PF13567.1 EGG05690.1 - 9.2 5.6 8.5 9.4 5.6 4.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Fusion_gly PF00523.13 EGG05693.1 - 0.071 11.1 0.2 0.1 10.6 0.1 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 HupH_C PF04809.8 EGG05696.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region TPT PF03151.11 EGG05698.1 - 5.9e-17 61.7 9.5 5.9e-17 61.7 6.6 3.1 1 1 1 2 2 2 1 Triose-phosphate Transporter family TPR_11 PF13414.1 EGG05699.1 - 2.2e-29 100.9 24.4 7e-08 32.0 1.0 9.7 7 4 4 11 11 11 8 TPR repeat TPR_17 PF13431.1 EGG05699.1 - 2.3e-25 86.6 4.7 0.00039 20.4 0.0 12.5 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGG05699.1 - 3.9e-23 79.4 21.8 0.00054 19.6 0.1 12.5 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGG05699.1 - 1.3e-22 78.3 4.8 0.00068 19.1 0.1 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGG05699.1 - 7.9e-19 67.8 22.9 1.4e-06 28.8 1.9 8.7 6 2 3 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGG05699.1 - 1.9e-16 59.0 14.6 0.0049 17.3 0.0 10.2 8 3 2 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGG05699.1 - 4.8e-15 55.2 26.5 0.44 10.5 0.0 10.8 9 3 2 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.1 EGG05699.1 - 8.5e-15 53.3 9.2 0.045 13.5 0.0 10.7 10 1 1 11 11 11 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGG05699.1 - 2e-10 39.6 7.9 0.59 10.0 0.0 9.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGG05699.1 - 9.6e-09 34.9 4.8 0.031 14.1 0.6 5.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGG05699.1 - 9.2e-07 29.1 27.3 0.14 12.5 0.5 9.8 10 2 3 13 13 10 2 Tetratricopeptide repeat BTAD PF03704.12 EGG05699.1 - 4.3e-05 23.8 8.4 0.29 11.4 1.1 4.6 3 1 0 3 3 3 2 Bacterial transcriptional activator domain TPR_6 PF13174.1 EGG05699.1 - 0.0046 17.3 13.6 8.3 7.1 0.0 9.9 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGG05699.1 - 0.0077 16.1 4.4 3.7 7.6 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Peptidase_C30 PF05409.8 EGG05699.1 - 0.034 13.2 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 Glyco_hyd_65N_2 PF14498.1 EGG05699.1 - 0.044 13.4 0.1 0.082 12.5 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Sec7 PF01369.15 EGG05700.1 - 7.7e-59 198.5 0.0 1.8e-58 197.3 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EGG05700.1 - 1.5e-17 63.5 0.8 2.4e-11 43.3 0.4 3.0 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGG05700.1 - 0.061 12.8 2.7 0.87 9.1 0.0 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF1981) F-box-like PF12937.2 EGG05701.1 - 0.0026 17.4 0.2 0.005 16.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGG05701.1 - 0.039 13.6 1.2 0.11 12.1 0.2 2.2 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.11 EGG05702.1 - 1.5e-28 99.5 28.5 1.9e-28 99.2 19.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG05702.1 - 7.7e-07 28.0 2.4 7.7e-07 28.0 1.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter UNC-93 PF05978.11 EGG05702.1 - 0.0075 15.7 1.1 0.022 14.2 0.8 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 QCR10 PF09796.4 EGG05703.1 - 1.1e-19 69.8 0.0 1.3e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 EGG05703.1 - 0.17 11.6 0.7 0.27 10.9 0.5 1.5 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein UBN2_3 PF14244.1 EGG05705.1 - 0.029 13.9 0.3 0.22 11.0 0.2 2.3 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type ECH PF00378.15 EGG05706.1 - 2.7e-14 52.8 0.1 4.2e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Formyl_trans_N PF00551.14 EGG05706.1 - 7.8e-13 48.3 0.1 5.2e-11 42.4 0.0 3.0 1 1 1 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.13 EGG05706.1 - 0.00046 20.2 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Cu-oxidase_3 PF07732.10 EGG05707.1 - 5.3e-29 100.3 1.0 1.5e-28 98.8 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EGG05707.1 - 6.5e-29 100.8 0.2 8.3e-27 94.0 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG05707.1 - 1.5e-26 92.5 5.5 3.9e-21 75.0 0.9 4.8 3 2 0 3 3 3 2 Multicopper oxidase Pkinase PF00069.20 EGG05709.1 - 2.2e-54 184.3 0.0 3.6e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG05709.1 - 3.2e-23 82.1 0.0 1.7e-22 79.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EGG05709.1 - 0.1 11.9 0.1 0.25 10.6 0.0 1.7 1 0 0 1 1 1 0 RIO1 family DUF4391 PF14335.1 EGG05710.1 - 0.056 12.8 0.9 1.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) DUF3788 PF12663.2 EGG05710.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) CAML PF14963.1 EGG05710.1 - 0.16 11.3 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Tannase PF07519.6 EGG05711.1 - 2.3e-75 254.1 0.0 3.8e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase UPF0113 PF03657.8 EGG05712.1 - 5.8e-11 42.3 0.0 7e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PP1 PF07430.6 EGG05712.1 - 0.041 13.4 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 Dynein_light PF01221.13 EGG05713.1 - 7.8e-38 128.3 0.1 9.1e-38 128.1 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 EGG05713.1 - 0.092 13.0 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Ground-like domain TPR_11 PF13414.1 EGG05714.1 - 1.7e-26 91.6 2.3 1.6e-09 37.2 0.7 3.0 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EGG05714.1 - 1.3e-19 68.4 2.0 3e-06 26.6 0.0 4.5 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGG05714.1 - 1.8e-16 58.9 5.4 2.4e-06 26.9 0.0 4.9 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGG05714.1 - 8e-14 50.6 2.2 6.1e-05 22.8 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGG05714.1 - 8.4e-13 48.4 0.3 4.5e-05 23.6 0.4 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG05714.1 - 2.7e-12 46.4 0.0 5.2e-06 26.3 0.0 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGG05714.1 - 1.9e-11 44.2 0.1 7.5e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGG05714.1 - 5.3e-10 39.0 0.0 0.019 15.5 0.0 4.0 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGG05714.1 - 6.1e-10 38.1 3.4 0.023 14.4 0.0 4.4 3 1 2 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EGG05714.1 - 2e-05 24.6 0.1 0.0019 18.3 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EGG05714.1 - 2.2e-05 24.6 0.1 0.62 10.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGG05714.1 - 0.00056 19.7 4.5 0.076 12.9 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGG05714.1 - 0.00086 18.4 0.1 0.0012 17.9 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.1 EGG05714.1 - 0.0012 18.9 1.1 0.0064 16.5 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGG05714.1 - 0.0014 18.4 0.0 0.22 11.3 0.0 2.7 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGG05714.1 - 0.0019 17.8 0.4 8.1 6.5 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.3 EGG05714.1 - 0.022 13.5 0.3 3.6 6.2 0.1 2.0 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_3 PF07720.7 EGG05714.1 - 0.026 14.3 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.4 EGG05714.1 - 0.07 13.0 0.3 4.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.1 EGG05714.1 - 0.076 12.1 0.1 0.65 9.0 0.0 2.0 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP MIT PF04212.13 EGG05714.1 - 0.12 12.2 2.3 14 5.6 0.0 3.1 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain CMV_1a PF12467.3 EGG05716.1 - 0.007 16.7 7.5 0.0078 16.5 5.2 1.1 1 0 0 1 1 1 1 Cucumber mosaic virus 1a protein family DUF4472 PF14739.1 EGG05716.1 - 0.096 13.1 5.0 0.12 12.7 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) FAM60A PF15396.1 EGG05716.1 - 0.098 12.3 3.6 0.11 12.2 2.5 1.0 1 0 0 1 1 1 0 Protein Family FAM60A SpoVR PF04293.8 EGG05716.1 - 0.15 10.3 3.9 0.17 10.1 2.7 1.0 1 0 0 1 1 1 0 SpoVR like protein PTPlike_phytase PF14566.1 EGG05716.1 - 0.17 11.9 0.8 0.18 11.8 0.6 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF4463 PF14703.1 EGG05716.1 - 0.25 11.8 3.9 0.33 11.4 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) CDC45 PF02724.9 EGG05716.1 - 0.28 9.1 5.2 0.31 9.0 3.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Rtf2 PF04641.7 EGG05716.1 - 0.7 9.0 10.7 0.82 8.8 7.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3464 PF11947.3 EGG05716.1 - 2.8 7.3 7.8 4.7 6.6 5.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) zf-C2H2 PF00096.21 EGG05720.1 - 4.4e-11 42.4 13.0 2.4e-05 24.4 1.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG05720.1 - 1.8e-09 37.4 17.2 1.8e-07 31.0 1.4 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGG05720.1 - 5.8e-07 29.4 11.3 0.0034 17.6 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGG05720.1 - 0.015 15.1 6.1 0.032 14.1 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CHY PF05495.7 EGG05720.1 - 0.062 13.4 1.4 0.14 12.3 1.0 1.5 1 0 0 1 1 1 0 CHY zinc finger GAGA PF09237.6 EGG05720.1 - 0.1 12.1 1.2 0.28 10.7 0.8 1.7 1 0 0 1 1 1 0 GAGA factor zf-BED PF02892.10 EGG05720.1 - 0.8 9.5 6.9 0.66 9.7 1.5 2.4 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 EGG05720.1 - 0.98 9.6 5.6 5.3 7.3 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding A2L_zn_ribbon PF08792.5 EGG05720.1 - 2.7 7.5 7.6 13 5.4 0.2 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain Aldedh PF00171.17 EGG05721.1 - 2.9e-124 414.9 0.0 3.3e-124 414.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGG05721.1 - 1.6e-06 27.1 0.1 1.6e-05 23.8 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Zn_clus PF00172.13 EGG05723.1 - 0.5 10.3 7.1 2.9 7.8 1.4 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_19 PF14559.1 EGG05724.1 - 1.7e-07 31.4 0.3 0.033 14.5 0.0 3.5 2 2 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.26 EGG05724.1 - 2.1e-07 30.5 0.0 5.3e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.1 EGG05724.1 - 4.2e-05 23.4 4.8 0.063 13.2 0.2 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGG05724.1 - 7.4e-05 23.0 0.5 2.3 9.1 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGG05724.1 - 0.0015 18.8 0.4 29 5.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EGG05724.1 - 0.0021 18.1 3.8 1.4 9.0 0.0 3.6 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGG05724.1 - 0.0057 17.2 0.6 5.8 7.7 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG05724.1 - 0.0073 16.0 0.3 12 5.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGG05724.1 - 0.11 12.4 0.0 20 5.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Pentaxin PF00354.12 EGG05725.1 - 0.042 13.2 0.1 0.07 12.5 0.1 1.3 1 0 0 1 1 1 0 Pentaxin family DUF1664 PF07889.7 EGG05726.1 - 9.2 6.0 14.8 0.47 10.2 0.9 4.0 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Zn_clus PF00172.13 EGG05727.1 - 5e-05 23.1 13.1 9.3e-05 22.2 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VCX_VCY PF15231.1 EGG05727.1 - 0.02 15.2 2.3 0.035 14.5 1.6 1.3 1 0 0 1 1 1 0 Variable charge X/Y family Fungal_trans PF04082.13 EGG05727.1 - 0.026 13.4 0.0 0.026 13.4 0.0 2.8 4 0 0 4 4 4 0 Fungal specific transcription factor domain Tmemb_14 PF03647.8 EGG05728.1 - 1.5e-17 63.7 5.2 1.8e-17 63.5 3.6 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF3188 PF11384.3 EGG05728.1 - 0.031 13.8 2.3 0.051 13.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) 5TM-5TMR_LYT PF07694.7 EGG05728.1 - 0.68 9.2 5.0 0.82 8.9 3.5 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT SWIB PF02201.13 EGG05731.1 - 0.052 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 SWIB/MDM2 domain OPT PF03169.10 EGG05733.1 - 1.6e-110 370.4 37.7 5.5e-110 368.6 26.1 1.7 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Apolipoprotein PF01442.13 EGG05734.1 - 5.8e-05 22.7 25.5 5.8e-05 22.7 17.7 5.2 1 1 4 5 5 5 2 Apolipoprotein A1/A4/E domain Filament PF00038.16 EGG05734.1 - 0.017 14.5 124.5 0.25 10.7 29.9 5.4 1 1 4 5 5 5 0 Intermediate filament protein MtrG PF04210.8 EGG05734.1 - 0.46 10.1 0.8 1.7 8.3 0.1 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G LPP PF04728.8 EGG05734.1 - 3 7.7 17.7 0.43 10.4 1.1 5.4 5 1 1 6 6 6 0 Lipoprotein leucine-zipper DSHCT PF08148.7 EGG05735.1 - 8.4e-55 184.7 0.3 2.3e-54 183.3 0.1 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EGG05735.1 - 5.5e-21 74.7 0.0 1.4e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 EGG05735.1 - 1.1e-11 44.3 0.0 1.9e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 EGG05735.1 - 4.2e-06 26.5 0.0 1.6e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF3516 PF12029.3 EGG05735.1 - 0.0016 17.3 0.4 0.0031 16.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3516) ResIII PF04851.10 EGG05735.1 - 0.0096 15.7 0.0 0.048 13.4 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Matrilin_ccoil PF10393.4 EGG05736.1 - 0.0095 15.2 3.3 0.78 9.1 0.2 2.4 2 0 0 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin Laminin_II PF06009.7 EGG05736.1 - 0.036 13.8 0.7 0.32 10.7 0.1 2.2 2 0 0 2 2 2 0 Laminin Domain II NPV_P10 PF05531.7 EGG05736.1 - 0.17 12.1 0.3 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 EGG05736.1 - 0.38 8.5 1.4 0.32 8.7 0.2 1.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GP41 PF00517.12 EGG05736.1 - 3.5 7.1 6.2 3.7 7.0 0.1 2.6 3 0 0 3 3 3 0 Retroviral envelope protein DUF1789 PF08748.6 EGG05737.1 - 0.15 12.1 0.1 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1789) LigB PF02900.13 EGG05738.1 - 6.8e-35 120.3 0.0 8.4e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF1510 PF07423.6 EGG05739.1 - 6.6 6.0 15.3 12 5.1 10.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TMEM247 PF15444.1 EGG05739.1 - 8.7 6.1 7.9 8.6 6.1 5.1 1.3 1 1 0 1 1 1 0 Transmembrane protein 247 Herpes_BLLF1 PF05109.8 EGG05740.1 - 6.5 4.5 18.9 7.7 4.3 13.1 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) ATS PF15445.1 EGG05741.1 - 0.089 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 MIP PF00230.15 EGG05742.1 - 6.4e-45 153.3 18.5 7.4e-45 153.1 12.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein ATPase_gene1 PF09527.5 EGG05742.1 - 0.06 13.1 0.9 0.06 13.1 0.6 4.6 5 1 1 6 6 6 0 Putative F0F1-ATPase subunit (ATPase_gene1) DUF4271 PF14093.1 EGG05742.1 - 3.4 7.2 10.2 0.77 9.3 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) DUF1056 PF06341.6 EGG05742.1 - 5.2 7.1 11.5 0.27 11.2 3.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1056) DUF4128 PF13554.1 EGG05743.1 - 0.0025 17.4 0.1 0.0034 17.0 0.1 1.3 1 0 0 1 1 1 1 Bacteriophage related domain of unknown function Glyco_hydro_81 PF03639.8 EGG05744.1 - 7.9e-129 430.7 0.0 9.8e-129 430.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Myosin_tail_1 PF01576.14 EGG05745.1 - 4.1e-05 21.5 113.9 4.1e-05 21.5 79.0 4.3 1 1 3 4 4 4 1 Myosin tail ATG16 PF08614.6 EGG05745.1 - 0.00011 22.0 28.9 0.00011 22.0 20.0 13.3 2 1 10 13 13 13 1 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 EGG05745.1 - 0.0003 19.4 28.6 0.0003 19.4 19.8 7.1 3 2 4 7 7 7 4 AAA domain TPR_MLP1_2 PF07926.7 EGG05745.1 - 0.0025 17.5 17.7 0.0025 17.5 12.2 13.7 1 1 14 15 15 15 2 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 EGG05745.1 - 0.0074 16.2 15.2 0.0074 16.2 10.5 13.6 2 2 13 15 15 15 4 Domain of unknown function (DUF4200) IncA PF04156.9 EGG05745.1 - 0.067 12.7 308.3 0.23 11.0 10.1 12.4 1 1 11 12 12 12 0 IncA protein WD40 PF00400.27 EGG05746.1 - 6.6e-18 63.8 12.6 0.00019 21.1 0.3 6.1 4 1 1 5 5 5 5 WD domain, G-beta repeat SRA1 PF07304.6 EGG05746.1 - 3.3e-05 23.6 0.0 3.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Apc4_WD40 PF12894.2 EGG05746.1 - 0.00029 20.2 0.1 0.36 10.3 0.0 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.10 EGG05746.1 - 0.0057 16.4 0.7 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 Prp18 domain WD40 PF00400.27 EGG05747.1 - 1.2e-18 66.1 0.6 1.5e-11 43.6 0.1 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 EGG05747.1 - 0.0071 14.5 0.0 0.0071 14.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 UBN2 PF14223.1 EGG05749.1 - 2.1e-05 24.2 0.4 3.9e-05 23.4 0.3 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EGG05749.1 - 5.4e-05 22.7 0.2 0.00046 19.7 0.1 2.2 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG05749.1 - 8.9e-05 22.0 0.2 0.00019 20.9 0.2 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF3046 PF11248.3 EGG05751.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) DUF747 PF05346.6 EGG05753.1 - 4.6e-99 331.5 1.8 6.6e-99 331.1 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family LSM PF01423.17 EGG05753.1 - 1.6e-17 62.7 0.1 4.1e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 LSM domain AAA_12 PF13087.1 EGG05755.1 - 1.3e-47 161.7 0.0 2.1e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGG05755.1 - 6.1e-32 111.0 0.1 1.9e-15 57.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 EGG05755.1 - 2.5e-14 53.2 0.0 2.5e-13 50.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGG05755.1 - 5.2e-11 42.1 0.1 2e-10 40.2 0.1 2.0 2 0 0 2 2 1 1 Part of AAA domain zf-met PF12874.2 EGG05755.1 - 6.7e-07 29.3 2.4 3.6e-05 23.7 0.8 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type UvrD-helicase PF00580.16 EGG05755.1 - 1.6e-06 27.6 0.0 0.00057 19.2 0.0 2.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EGG05755.1 - 5.5e-06 26.0 0.0 0.0005 19.6 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DEAD PF00270.24 EGG05755.1 - 0.00028 20.4 0.0 0.001 18.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGG05755.1 - 0.00057 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGG05755.1 - 0.0012 18.9 0.0 0.0053 16.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EGG05755.1 - 0.0021 17.3 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein zf-C2H2_jaz PF12171.3 EGG05755.1 - 0.0027 17.8 3.8 0.0034 17.4 0.6 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding AAA_16 PF13191.1 EGG05755.1 - 0.004 17.1 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.9 EGG05755.1 - 0.0044 16.6 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Helicase AAA PF00004.24 EGG05755.1 - 0.016 15.4 0.0 0.17 12.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGG05755.1 - 0.028 13.8 0.0 0.063 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-U1 PF06220.7 EGG05755.1 - 0.047 13.2 1.0 0.15 11.6 0.2 2.2 2 0 0 2 2 2 0 U1 zinc finger Arch_ATPase PF01637.13 EGG05755.1 - 0.055 13.1 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase UvrD_C_2 PF13538.1 EGG05755.1 - 0.064 13.4 0.1 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Phage_connector PF05352.7 EGG05755.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Phage Connector (GP10) AKAP95 PF04988.7 EGG05755.1 - 0.16 11.7 2.1 3.8 7.2 0.4 2.3 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF2075 PF09848.4 EGG05755.1 - 0.18 10.7 0.0 0.4 9.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EGG05755.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.9 EGG05755.1 - 0.19 10.6 0.0 12 4.7 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase SGL PF08450.7 EGG05756.1 - 0.019 14.3 0.0 2.6 7.3 0.0 2.5 2 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region DUF1431 PF07248.7 EGG05757.1 - 0.053 13.5 0.1 0.072 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1431) Toxin_7 PF05980.7 EGG05757.1 - 1.4 9.0 3.8 0.78 9.8 0.8 1.9 1 1 1 2 2 2 0 Toxin 7 FBA_3 PF08268.7 EGG05758.1 - 0.094 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 F-box associated domain DUF2781 PF10914.3 EGG05759.1 - 1.3e-16 60.7 4.5 5.5e-16 58.6 2.9 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2781) HSP20 PF00011.16 EGG05760.1 - 2.9e-21 75.2 0.2 3.5e-21 74.9 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Coatomer_E PF04733.9 EGG05763.1 - 6.7e-43 146.9 0.5 8.2e-43 146.6 0.3 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit Apc3 PF12895.2 EGG05763.1 - 6e-08 32.7 0.1 0.00069 19.6 0.0 3.9 3 2 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGG05763.1 - 4.7e-07 29.8 1.6 0.17 12.6 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGG05763.1 - 1e-06 28.9 5.3 0.07 13.4 0.2 4.3 3 3 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGG05763.1 - 9.1e-05 22.0 0.2 0.026 14.4 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGG05763.1 - 9.2e-05 22.3 1.1 1.2 9.0 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGG05763.1 - 0.0011 18.4 0.1 0.029 13.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGG05763.1 - 0.0012 19.4 5.4 0.18 12.5 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGG05763.1 - 0.01 15.4 0.1 1.5 8.5 0.0 3.9 5 0 0 5 5 5 0 TPR repeat zf-AN1 PF01428.11 EGG05764.1 - 1.6 8.7 8.0 0.13 12.1 1.4 2.3 2 2 0 2 2 2 0 AN1-like Zinc finger Prenyltransf PF01255.14 EGG05767.1 - 1.1e-70 237.2 0.0 8.4e-70 234.3 0.0 1.9 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase zf-C2H2 PF00096.21 EGG05770.1 - 6.1e-10 38.8 7.8 0.0016 18.6 0.0 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG05770.1 - 9.3e-10 38.3 4.0 0.0016 18.6 0.9 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGG05770.1 - 1.5e-07 31.2 9.4 0.013 15.8 0.0 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGG05770.1 - 0.25 11.3 2.2 0.7 9.8 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger Aldo_ket_red PF00248.16 EGG05772.1 - 1.3e-43 148.9 0.3 1.7e-43 148.4 0.2 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Hormone_recep PF00104.25 EGG05772.1 - 0.0073 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor PAR1 PF06521.6 EGG05772.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 PAR1 protein DUF1805 PF08827.6 EGG05772.1 - 0.1 12.4 0.4 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) ADH_zinc_N PF00107.21 EGG05772.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UBN2_2 PF14227.1 EGG05773.1 - 2.7e-05 23.7 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGG05773.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Radical_SAM PF04055.16 EGG05774.1 - 3.6e-10 40.2 0.0 1.1e-09 38.6 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily SR-25 PF10500.4 EGG05774.1 - 7.2 6.0 5.9 11 5.4 4.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Lactamase_B_2 PF12706.2 EGG05775.1 - 2e-08 34.0 1.1 9.4e-08 31.8 0.3 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DRMBL PF07522.9 EGG05775.1 - 0.00012 22.0 0.3 0.0009 19.2 0.2 2.5 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase VirionAssem_T7 PF11653.3 EGG05776.1 - 0.043 14.5 0.0 0.06 14.1 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein adh_short PF00106.20 EGG05777.1 - 8.3e-12 45.3 0.2 5.4e-11 42.7 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG05777.1 - 0.00016 21.3 0.1 0.047 13.3 0.0 2.2 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 EGG05777.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Glyco_hydro_76 PF03663.9 EGG05778.1 - 1.3e-49 169.6 12.3 2.4e-49 168.6 8.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 PAXNEB PF05625.6 EGG05779.1 - 3e-55 187.5 0.0 1.3e-54 185.4 0.0 1.7 1 1 0 1 1 1 1 PAXNEB protein KaiC PF06745.8 EGG05779.1 - 0.00036 19.7 0.0 0.00067 18.8 0.0 1.5 1 0 0 1 1 1 1 KaiC Glyco_hydro_61 PF03443.9 EGG05780.1 - 1.8e-20 73.7 0.0 4.3e-20 72.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 CFEM PF05730.6 EGG05780.1 - 9.7e-05 22.1 4.4 9.7e-05 22.1 3.1 1.8 2 0 0 2 2 2 1 CFEM domain RhoGEF PF00621.15 EGG05781.1 - 2.4e-38 131.8 0.0 7.6e-38 130.1 0.0 2.0 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 EGG05781.1 - 1.9e-11 43.2 1.1 7.5e-05 22.2 0.0 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGG05781.1 - 0.014 15.3 1.2 12 6.4 0.2 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat DUF1574 PF07611.6 EGG05781.1 - 0.38 9.5 0.3 0.64 8.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) Ras PF00071.17 EGG05782.1 - 5.1e-57 191.7 0.0 6.4e-57 191.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG05782.1 - 1.4e-18 67.5 0.0 2.2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG05782.1 - 3.6e-16 58.8 0.0 4e-15 55.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGG05782.1 - 1.2e-06 27.8 0.0 1.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGG05782.1 - 0.00099 18.5 0.0 0.002 17.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGG05782.1 - 0.0019 18.1 0.0 0.0041 17.0 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SSP160 PF06933.6 EGG05782.1 - 0.0034 15.4 6.3 0.005 14.8 4.3 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 AAA_16 PF13191.1 EGG05782.1 - 0.034 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain eIF2A PF08662.6 EGG05783.1 - 3e-39 134.7 0.8 5.3e-37 127.4 0.2 3.1 2 2 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 EGG05783.1 - 5e-05 23.2 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGG05783.1 - 0.0002 20.8 0.0 0.0005 19.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGG05783.1 - 0.00033 20.4 0.2 5.9 6.9 0.1 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat RRM_5 PF13893.1 EGG05783.1 - 0.00038 20.2 0.0 0.00098 18.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.7 EGG05783.1 - 0.029 12.2 0.2 3.4 5.3 0.0 2.2 2 0 0 2 2 2 0 IKI3 family Pkinase PF00069.20 EGG05784.1 - 5.2e-09 35.6 0.1 6.9e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EGG05784.1 - 2.7e-07 29.8 0.0 7.7e-07 28.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGG05784.1 - 5.2e-07 29.1 0.0 7.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EGG05784.1 - 7.9e-05 21.8 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.15 EGG05784.1 - 0.00071 18.7 0.1 0.0015 17.7 0.1 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 EGG05784.1 - 0.00078 19.2 0.0 0.0087 15.8 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF2036 PF09724.4 EGG05784.1 - 0.06 12.4 0.0 0.099 11.7 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2036) Pkinase PF00069.20 EGG05785.1 - 3.4e-54 183.7 0.0 4.2e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG05785.1 - 5.6e-26 91.1 0.0 7e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG05785.1 - 0.00016 21.5 0.0 0.01 15.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGG05785.1 - 0.062 12.2 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Fer4_NifH PF00142.13 EGG05785.1 - 0.094 11.8 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family vMSA PF00695.14 EGG05787.1 - 0.038 13.1 0.8 0.3 10.2 0.5 1.9 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus DSPc PF00782.15 EGG05788.1 - 4.5e-24 84.5 0.0 1.1e-14 54.2 0.0 3.6 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGG05788.1 - 0.028 13.7 0.1 0.08 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGG05788.1 - 0.054 13.5 0.2 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate PGAP1 PF07819.8 EGG05789.1 - 2.1e-71 240.0 0.0 3.2e-71 239.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGG05789.1 - 0.0082 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG05789.1 - 0.0098 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EGG05789.1 - 0.038 13.2 0.1 0.075 12.3 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.10 EGG05789.1 - 0.2 10.6 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Mpv17_PMP22 PF04117.7 EGG05791.1 - 0.0023 17.5 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family BSP_II PF05432.6 EGG05793.1 - 0.00017 20.9 2.5 0.00017 20.9 1.7 2.2 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) zf-C2H2_4 PF13894.1 EGG05793.1 - 0.2 12.0 4.9 0.55 10.6 3.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGG05793.1 - 0.58 10.6 8.2 0.089 13.1 2.6 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosomal_60s PF00428.14 EGG05793.1 - 0.84 10.0 15.7 1.8 8.9 1.3 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Saw1 PF11561.3 EGG05793.1 - 3.9 6.8 7.3 3.4 6.9 0.2 2.3 2 0 0 2 2 2 0 Single strand annealing-weakened 1 GPI-anchored PF10342.4 EGG05794.1 - 4.3e-09 36.7 0.4 7.8e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cpn60_TCP1 PF00118.19 EGG05795.1 - 2.9e-142 474.7 4.4 3.3e-142 474.5 3.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Polysacc_deac_1 PF01522.16 EGG05796.1 - 1.2e-25 89.5 0.0 2e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Complex1_51K PF01512.12 EGG05797.1 - 4e-48 162.9 0.0 6.1e-48 162.3 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EGG05797.1 - 6e-20 70.1 0.4 1.2e-19 69.1 0.3 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EGG05797.1 - 8.5e-07 28.7 0.0 1.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 SLBB domain zf-C2H2 PF00096.21 EGG05799.1 - 1.5e-07 31.3 17.5 8e-07 29.0 0.7 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG05799.1 - 7.2e-07 29.1 2.6 7.2e-07 29.1 1.8 3.2 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGG05799.1 - 0.00021 21.3 1.2 0.00065 19.7 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EGG05799.1 - 0.00057 20.0 0.4 0.00057 20.0 0.3 2.9 3 1 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 EGG05799.1 - 0.00094 19.3 5.0 0.0038 17.3 0.2 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Pneumo_phosprot PF02478.11 EGG05800.1 - 2.7 7.4 12.0 7.2 6.0 8.3 1.7 1 0 0 1 1 1 0 Pneumovirus phosphoprotein AOX PF01786.12 EGG05801.1 - 0.088 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Alternative oxidase Hyccin PF09790.4 EGG05803.1 - 0.082 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Hyccin LSM PF01423.17 EGG05805.1 - 1.5e-15 56.4 0.4 2.8e-15 55.6 0.3 1.4 1 0 0 1 1 1 1 LSM domain CLU PF13236.1 EGG05808.1 - 1.1e-55 188.5 0.0 2e-55 187.5 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EGG05808.1 - 6.7e-40 136.7 0.0 1.8e-39 135.4 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EGG05808.1 - 6.5e-10 38.8 2.6 0.0021 17.9 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat DUF727 PF05303.7 EGG05808.1 - 3e-05 23.7 0.0 7.6e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_10 PF13374.1 EGG05808.1 - 0.0056 16.5 1.4 11 6.0 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Tetraspannin PF00335.15 EGG05809.1 - 4.2 6.5 16.3 2.6 7.2 5.4 2.8 1 1 1 3 3 3 0 Tetraspanin family DUF3918 PF13056.1 EGG05809.1 - 7.9 5.8 5.4 2.7 7.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) DEAD PF00270.24 EGG05811.1 - 1.3e-43 148.4 0.0 3.8e-43 146.9 0.0 1.8 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG05811.1 - 4.1e-24 84.2 0.0 1e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EGG05811.1 - 1.1e-06 27.2 0.0 0.00016 20.2 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EGG05811.1 - 0.2 11.7 3.8 0.15 12.1 0.3 2.6 2 1 0 2 2 2 0 AAA domain Ku_N PF03731.10 EGG05812.1 - 1.5 8.1 7.8 3.9 6.8 2.1 2.7 1 1 0 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain Pkinase PF00069.20 EGG05814.1 - 1.6e-22 79.9 0.0 2e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG05814.1 - 2e-13 50.0 0.0 2.6e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_transf_41 PF13844.1 EGG05815.1 - 7e-76 255.0 0.1 8.8e-47 159.1 0.0 3.0 3 0 0 3 3 3 3 Glycosyl transferase family 41 NUDIX PF00293.23 EGG05817.1 - 6e-12 45.3 0.0 1.1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EGG05817.1 - 1.2e-10 41.5 0.0 3.6e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EGG05817.1 - 0.00012 21.4 1.1 0.00021 20.7 0.8 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Alpha-L-AF_C PF06964.7 EGG05819.1 - 4.5e-09 36.3 0.0 3.1e-05 23.8 0.0 2.4 1 1 1 2 2 2 2 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 EGG05819.1 - 0.0011 19.0 0.1 0.0033 17.4 0.0 1.8 2 0 0 2 2 2 1 Carbohydrate binding domain Ribosomal_S7 PF00177.16 EGG05820.1 - 4.5e-40 136.6 1.1 5.3e-40 136.3 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e COX6B PF02297.12 EGG05821.1 - 3.2e-19 68.7 3.2 4.3e-19 68.3 2.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb EB1 PF03271.12 EGG05822.1 - 4.8e-14 52.1 0.2 1.1e-13 50.9 0.2 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EGG05822.1 - 1.2e-07 31.7 0.3 2.2e-07 30.8 0.2 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF4296 PF14129.1 EGG05822.1 - 0.069 13.2 1.6 0.084 13.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) zf-met2 PF12907.2 EGG05823.1 - 2.8e-09 36.7 2.9 5.6e-09 35.8 2.0 1.5 1 0 0 1 1 1 1 Zinc-binding DUF2404 PF10296.4 EGG05824.1 - 4.8e-28 97.1 0.0 8.9e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 EGG05824.1 - 0.0042 17.2 1.6 0.017 15.3 0.0 2.8 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 EGG05824.1 - 0.052 13.7 0.0 0.18 12.0 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain Ribosomal_L28e PF01778.12 EGG05825.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L28e protein family DUF2648 PF10855.3 EGG05829.1 - 0.17 11.3 0.6 0.34 10.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) FHA PF00498.21 EGG05830.1 - 3.6e-09 36.5 0.0 6.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain PI3_PI4_kinase PF00454.22 EGG05832.1 - 8.7e-29 100.6 0.1 5.2e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EGG05832.1 - 0.0002 20.7 0.1 0.00052 19.3 0.1 1.7 1 0 0 1 1 1 1 FATC domain Bromo_TP PF07524.8 EGG05834.1 - 0.034 13.8 0.1 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Bromodomain associated Nic96 PF04097.9 EGG05836.1 - 9.8e-22 76.8 0.6 2.4e-19 68.9 0.1 2.1 1 1 1 2 2 2 2 Nup93/Nic96 Apc3 PF12895.2 EGG05836.1 - 0.044 13.9 0.1 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF104 PF01954.11 EGG05836.1 - 0.15 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF104 RAP1 PF07218.6 EGG05838.1 - 0.00079 17.6 11.3 0.0012 17.0 7.8 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Syntaxin-6_N PF09177.6 EGG05838.1 - 0.032 14.6 4.2 0.07 13.5 2.9 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TBPIP PF07106.8 EGG05838.1 - 0.16 11.4 7.3 0.34 10.4 5.0 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 EGG05838.1 - 0.44 8.9 4.9 0.64 8.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AATF-Che1 PF13339.1 EGG05838.1 - 3.9 7.6 10.2 0.78 9.9 4.0 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor GEMIN8 PF15348.1 EGG05838.1 - 5.3 7.0 13.3 3.1 7.8 7.7 1.5 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Myb_DNA-binding PF00249.26 EGG05839.1 - 0.0027 17.7 0.3 0.006 16.6 0.2 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain ICL PF00463.16 EGG05840.1 - 6.8e-252 836.3 0.1 7.7e-252 836.1 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EGG05840.1 - 2.1e-09 36.9 0.0 3.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 EGG05840.1 - 0.1 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain DUF1128 PF06569.6 EGG05841.1 - 0.1 12.3 0.2 20 4.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) Abhydrolase_6 PF12697.2 EGG05842.1 - 1.4e-14 54.5 1.0 8.1e-13 48.7 0.7 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG05842.1 - 1.8e-08 34.2 0.0 0.0044 16.7 0.0 2.6 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG05842.1 - 2.1e-05 24.2 0.1 6.1e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1057 PF06342.7 EGG05842.1 - 0.26 10.0 0.0 0.44 9.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) GARS_A PF01071.14 EGG05843.1 - 5.6e-81 270.7 0.0 9e-81 270.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EGG05843.1 - 1.9e-35 121.2 0.1 1.4e-34 118.4 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EGG05843.1 - 2.1e-31 109.0 0.0 4.2e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EGG05843.1 - 4e-27 94.2 0.1 1.1e-26 92.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EGG05843.1 - 4.5e-17 62.0 1.9 9.8e-17 60.9 0.6 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EGG05843.1 - 6.6e-12 45.5 0.0 1.4e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGG05843.1 - 1.4e-07 30.5 0.0 3.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EGG05843.1 - 3.2e-07 29.8 0.0 5.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGG05843.1 - 3.8e-06 26.8 0.0 9.5e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGG05843.1 - 1.6e-05 24.2 0.0 2.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EGG05843.1 - 0.0075 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGG05843.1 - 0.0076 15.6 0.1 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus SIS_2 PF13580.1 EGG05843.1 - 0.07 12.8 0.1 17 5.0 0.0 2.7 2 0 0 2 2 2 0 SIS domain ATP-grasp_2 PF08442.5 EGG05843.1 - 0.1 11.9 0.0 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain Glyco_hydro_9 PF00759.14 EGG05844.1 - 3.5e-95 319.5 14.7 4.1e-95 319.3 10.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Cu-oxidase_3 PF07732.10 EGG05845.1 - 1.8e-33 114.7 0.3 1.2e-32 112.1 0.1 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EGG05845.1 - 2.9e-31 108.5 0.1 3.4e-30 105.0 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG05845.1 - 2.9e-16 59.2 0.2 1.4e-09 37.5 0.0 3.9 4 0 0 4 4 4 2 Multicopper oxidase Claudin_3 PF06653.6 EGG05845.1 - 0.31 10.7 1.3 13 5.4 0.2 2.2 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Brix PF04427.13 EGG05846.1 - 1.5e-48 164.9 0.3 2.2e-48 164.4 0.2 1.2 1 0 0 1 1 1 1 Brix domain DUF2517 PF10725.4 EGG05846.1 - 0.051 13.2 1.2 0.092 12.4 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2517) Bromodomain PF00439.20 EGG05846.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Bromodomain Metal_resist PF13801.1 EGG05846.1 - 0.23 11.4 1.7 0.44 10.5 1.1 1.4 1 0 0 1 1 1 0 Heavy-metal resistance Mito_carr PF00153.22 EGG05847.1 - 3.7e-29 100.2 7.9 4.1e-12 45.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fasciclin PF02469.17 EGG05849.1 - 3.7e-25 88.3 0.3 2.2e-12 47.1 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain CFEM PF05730.6 EGG05849.1 - 0.072 12.9 4.2 0.15 11.8 2.9 1.6 1 0 0 1 1 1 0 CFEM domain DUF1162 PF06650.7 EGG05850.1 - 7.8e-68 228.6 0.0 4.3e-64 216.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EGG05850.1 - 7e-39 132.0 0.1 1.6e-38 130.8 0.1 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EGG05850.1 - 4.2e-05 23.6 0.0 0.0002 21.4 0.0 2.2 2 0 0 2 2 2 1 ATG C terminal domain Ribosomal_L32p PF01783.18 EGG05851.1 - 1.4e-15 57.1 3.1 2.5e-15 56.3 2.2 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family Med13_N PF11597.3 EGG05851.1 - 0.026 13.2 1.4 0.031 12.9 1.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Exo_endo_phos PF03372.18 EGG05852.1 - 1.6e-15 57.7 0.0 2.5e-15 57.0 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YodL PF14191.1 EGG05855.1 - 0.085 13.3 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 YodL-like LPP PF04728.8 EGG05855.1 - 0.12 12.2 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Ribosomal_S26e PF01283.14 EGG05861.1 - 0.0098 16.1 1.1 0.055 13.7 0.4 2.1 2 0 0 2 2 2 1 Ribosomal protein S26e FXR1P_C PF12235.3 EGG05861.1 - 0.13 12.3 0.7 0.17 12.0 0.5 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal F-box-like_2 PF13013.1 EGG05862.1 - 0.028 14.1 0.1 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 F-box-like domain LRR_8 PF13855.1 EGG05862.1 - 9.6 6.0 12.7 3.8 7.3 0.6 4.4 5 0 0 5 5 5 0 Leucine rich repeat Glyco_hydro_76 PF03663.9 EGG05863.1 - 9.1e-52 176.6 15.5 1.2e-51 176.2 10.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 EGG05863.1 - 0.012 13.9 2.9 0.11 10.7 0.6 2.8 2 1 1 4 4 4 0 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_47 PF01532.15 EGG05864.1 - 4.4e-109 365.1 0.1 6.1e-61 206.4 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Spb1_C PF07780.7 EGG05865.1 - 1.2e-58 198.1 31.4 1.2e-58 198.1 21.8 4.2 4 1 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.14 EGG05865.1 - 1.5e-52 178.1 0.1 6.1e-52 176.2 0.0 2.1 3 0 0 3 3 3 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EGG05865.1 - 3.3e-42 143.6 9.3 3.3e-42 143.6 6.4 6.0 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) HORMA PF02301.13 EGG05869.1 - 5.8e-18 65.1 0.0 8.1e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 HORMA domain DUF202 PF02656.10 EGG05870.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) GTP_EFTU PF00009.22 EGG05874.1 - 7.9e-63 211.2 0.2 1.1e-62 210.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGG05874.1 - 8.8e-34 115.6 0.0 2.1e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EGG05874.1 - 2.3e-21 75.4 0.0 6.1e-21 74.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EGG05874.1 - 4.1e-13 48.9 0.0 1.1e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EGG05874.1 - 1.1e-12 47.8 2.2 1.2e-12 47.8 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGG05874.1 - 1.2e-05 25.2 0.1 2.8e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGG05874.1 - 0.046 13.2 0.7 0.14 11.6 0.3 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Phosphodiest PF01663.17 EGG05875.1 - 4.4e-10 39.4 0.8 8.6e-10 38.4 0.5 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HSL_N PF06350.7 EGG05876.1 - 0.041 12.9 0.0 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 Hormone-sensitive lipase (HSL) N-terminus Peptidase_C42 PF05533.7 EGG05876.1 - 0.055 13.3 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 Peptidase_C42 PF05533.7 EGG05877.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 HSL_N PF06350.7 EGG05877.1 - 0.028 13.5 0.3 0.045 12.8 0.0 1.4 2 0 0 2 2 2 0 Hormone-sensitive lipase (HSL) N-terminus Benyvirus_P25 PF05744.6 EGG05877.1 - 0.12 11.6 0.6 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Benyvirus P25/P26 protein CDC27 PF09507.5 EGG05878.1 - 0.34 10.0 10.7 0.37 9.9 7.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_2 PF07724.9 EGG05880.1 - 1.3e-49 168.3 0.0 1.3e-46 158.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGG05880.1 - 1.1e-23 83.8 0.0 8.2e-12 45.4 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EGG05880.1 - 2.2e-23 81.9 0.4 1.6e-22 79.1 0.1 2.8 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 EGG05880.1 - 4.7e-18 64.8 3.6 7.9e-13 48.1 0.2 4.4 4 0 0 4 4 3 2 Clp amino terminal domain AAA_5 PF07728.9 EGG05880.1 - 5e-13 48.9 0.2 5.6e-07 29.3 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGG05880.1 - 9.6e-11 41.9 2.1 0.00075 19.6 0.0 4.9 3 2 1 4 4 3 2 AAA domain AAA_16 PF13191.1 EGG05880.1 - 1.7e-10 41.1 8.7 0.00055 19.9 0.0 5.1 3 3 2 6 6 6 2 AAA ATPase domain IstB_IS21 PF01695.12 EGG05880.1 - 2.1e-08 33.7 0.0 0.003 16.9 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.21 EGG05880.1 - 3.6e-08 33.0 0.0 6e-05 22.5 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.1 EGG05880.1 - 1.9e-07 31.4 0.0 0.012 15.8 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGG05880.1 - 7.9e-07 29.9 2.5 0.035 14.9 0.0 3.9 3 1 1 4 4 2 2 AAA domain Mg_chelatase PF01078.16 EGG05880.1 - 3e-05 23.2 0.0 0.049 12.7 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EGG05880.1 - 3e-05 22.9 1.0 0.11 11.2 0.0 3.2 3 1 0 4 4 4 2 TIP49 C-terminus AAA_28 PF13521.1 EGG05880.1 - 3.1e-05 23.9 0.2 0.35 10.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EGG05880.1 - 4.2e-05 23.4 0.0 0.13 12.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EGG05880.1 - 4.4e-05 23.1 0.4 0.22 11.2 0.0 3.2 3 0 0 3 3 2 2 Part of AAA domain RNA_helicase PF00910.17 EGG05880.1 - 7.9e-05 22.7 0.0 0.25 11.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.7 EGG05880.1 - 0.00025 20.1 1.6 1.8 7.5 0.0 4.2 5 0 0 5 5 5 2 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EGG05880.1 - 0.00026 20.6 0.0 0.052 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGG05880.1 - 0.00032 19.8 0.0 0.2 10.7 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 EGG05880.1 - 0.00052 19.5 0.4 1.1 8.6 0.0 3.7 2 1 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 EGG05880.1 - 0.00095 19.4 0.3 0.21 11.8 0.0 3.3 3 0 0 3 3 3 1 ABC transporter NACHT PF05729.7 EGG05880.1 - 0.0018 17.9 0.0 0.19 11.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 EGG05880.1 - 0.0026 17.4 0.0 0.8 9.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EGG05880.1 - 0.0027 17.1 0.1 2.1 7.6 0.0 3.2 2 1 0 2 2 2 1 AAA domain PhoH PF02562.11 EGG05880.1 - 0.0041 16.3 0.0 1.1 8.4 0.0 2.8 3 0 0 3 3 2 1 PhoH-like protein AAA_23 PF13476.1 EGG05880.1 - 0.005 17.1 7.3 1.6 9.0 0.0 4.0 3 1 0 3 3 3 1 AAA domain T2SE PF00437.15 EGG05880.1 - 0.0076 15.1 0.0 0.029 13.2 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 EGG05880.1 - 0.011 14.9 0.0 4.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ResIII PF04851.10 EGG05880.1 - 0.016 15.0 0.0 17 5.1 0.0 3.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Torsin PF06309.6 EGG05880.1 - 0.018 14.9 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 0 Torsin DUF2075 PF09848.4 EGG05880.1 - 0.02 13.8 0.0 1.1 8.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PEPCK_ATP PF01293.15 EGG05880.1 - 0.024 13.1 0.1 2.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase AAA_21 PF13304.1 EGG05880.1 - 0.025 14.5 0.0 1.4 8.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.15 EGG05880.1 - 0.028 14.0 0.0 0.6 9.7 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase NTPase_1 PF03266.10 EGG05880.1 - 0.03 14.0 1.1 9.8 5.8 0.0 4.1 5 0 0 5 5 4 0 NTPase AAA_29 PF13555.1 EGG05880.1 - 0.034 13.6 0.0 6.8 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain KTI12 PF08433.5 EGG05880.1 - 0.036 13.2 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_3 PF07726.6 EGG05880.1 - 0.037 13.6 0.0 23 4.6 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EGG05880.1 - 0.039 13.5 0.0 7.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FliJ PF02050.11 EGG05880.1 - 0.044 13.8 6.5 1.4 8.9 3.4 3.3 3 0 0 3 3 2 0 Flagellar FliJ protein Parvo_NS1 PF01057.12 EGG05880.1 - 0.14 10.9 0.0 4.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Mnd1 PF03962.10 EGG05880.1 - 0.21 11.2 3.6 0.55 9.8 2.5 1.8 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 EGG05880.1 - 0.66 9.5 6.2 1.8 8.1 4.3 1.7 1 0 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 EGG05880.1 - 2.1 8.2 14.1 0.032 14.0 4.0 2.3 3 0 0 3 3 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.1 EGG05880.1 - 2.8 7.9 5.6 8.1 6.4 0.4 2.9 2 1 2 4 4 3 0 FlxA-like protein ubiquitin PF00240.18 EGG05881.1 - 1e-237 768.0 40.1 1.7e-33 113.8 0.4 7.0 7 0 0 7 7 7 7 Ubiquitin family Rad60-SLD PF11976.3 EGG05881.1 - 1e-135 441.6 42.5 6.9e-19 67.3 0.6 7.0 7 0 0 7 7 7 7 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGG05881.1 - 2.3e-39 133.5 19.5 0.00059 20.0 0.1 9.1 7 7 0 7 7 7 7 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGG05881.1 - 3.6e-32 111.2 2.3 0.012 15.3 0.0 7.1 7 0 0 7 7 7 7 Telomere stability and silencing DUF2407 PF10302.4 EGG05881.1 - 1.7e-22 79.3 7.2 0.26 11.4 0.0 7.2 1 1 4 7 7 7 7 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGG05881.1 - 3.9e-21 75.0 12.7 0.31 10.9 0.0 8.0 7 0 0 7 7 7 7 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EGG05881.1 - 3.1e-16 59.1 0.0 6.1 6.9 0.0 7.8 7 0 0 7 7 7 7 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 EGG05881.1 - 6.5e-12 45.0 6.0 2.4 7.2 0.0 6.2 6 0 0 6 6 6 6 RNA methyltransferase FlgD_ig PF13860.1 EGG05881.1 - 1.4e-10 40.7 14.3 7.1 6.4 0.0 7.3 7 0 0 7 7 7 6 FlgD Ig-like domain TUG-UBL1 PF11470.3 EGG05881.1 - 1.4e-07 31.3 14.3 19 5.2 0.0 7.2 7 0 0 7 7 7 0 GLUT4 regulating protein TUG Big_3_3 PF13750.1 EGG05881.1 - 2.6e-06 26.9 0.2 39 3.6 0.0 6.6 7 0 0 7 7 7 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 EGG05881.1 - 7.3e-06 26.2 3.9 1.5e+02 2.8 0.0 7.0 7 0 0 7 7 7 0 ACT domain GABP-alpha PF11620.3 EGG05881.1 - 0.0041 17.0 15.6 79 3.3 0.0 6.8 7 0 0 7 7 7 0 GA-binding protein alpha chain Tash_PEST PF07708.6 EGG05881.1 - 0.047 13.6 56.9 6.6 6.8 1.2 7.3 7 0 0 7 7 7 0 Tash protein PEST motif Plexin_cytopl PF08337.7 EGG05881.1 - 0.051 11.8 31.4 13 3.9 0.2 10.1 8 6 0 8 8 8 0 Plexin cytoplasmic RasGAP domain Ipi1_N PF12333.3 EGG05882.1 - 4.1e-11 42.7 0.5 1.2e-08 34.8 0.2 3.9 3 1 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation MBOAT_2 PF13813.1 EGG05882.1 - 0.012 15.6 0.3 0.56 10.3 0.0 2.6 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family 4F5 PF04419.9 EGG05883.1 - 4e-07 30.6 9.6 7.2e-07 29.8 6.6 1.4 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.2 EGG05883.1 - 3e-05 23.8 0.4 5.9e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding zf-C2H2_4 PF13894.1 EGG05883.1 - 0.0045 17.2 0.1 0.0072 16.5 0.1 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger PT-HINT PF07591.6 EGG05883.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Pretoxin HINT domain DUF466 PF04328.8 EGG05883.1 - 0.22 11.3 0.8 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF466) zf-Di19 PF05605.7 EGG05883.1 - 0.24 11.5 1.0 0.42 10.7 0.7 1.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding ARID PF01388.16 EGG05884.1 - 5.7e-14 51.7 0.0 5.7e-14 51.7 0.0 2.6 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain IncA PF04156.9 EGG05885.1 - 0.00071 19.2 0.1 0.00089 18.8 0.1 1.1 1 0 0 1 1 1 1 IncA protein DUF4407 PF14362.1 EGG05885.1 - 0.021 13.7 1.7 0.021 13.7 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.3 EGG05885.1 - 0.029 14.2 3.8 0.04 13.8 2.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mnd1 PF03962.10 EGG05885.1 - 0.1 12.2 3.9 0.14 11.8 2.7 1.1 1 0 0 1 1 1 0 Mnd1 family SlyX PF04102.7 EGG05885.1 - 0.13 12.6 1.3 0.28 11.6 0.9 1.5 1 0 0 1 1 1 0 SlyX Vfa1 PF08432.5 EGG05885.1 - 0.23 11.4 13.8 0.32 11.0 9.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Spc24 PF08286.6 EGG05885.1 - 0.28 10.8 4.5 0.56 9.9 3.2 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Atg14 PF10186.4 EGG05885.1 - 0.3 9.9 3.8 0.41 9.5 2.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3987 PF13148.1 EGG05885.1 - 0.52 8.8 3.8 0.66 8.4 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Casc1 PF12366.3 EGG05885.1 - 1.6 8.1 7.0 2.3 7.6 4.9 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Ax_dynein_light PF10211.4 EGG05885.1 - 1.8 8.3 6.5 2.5 7.8 4.5 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain eIF-3c_N PF05470.7 EGG05885.1 - 2.2 6.2 8.0 2.6 6.0 5.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4337 PF14235.1 EGG05885.1 - 2.6 7.8 5.9 4 7.2 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Peptidase_S49_N PF08496.5 EGG05885.1 - 2.7 7.7 7.6 3.9 7.2 5.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Striatin PF08232.7 EGG05885.1 - 5.8 7.2 8.9 6.2 7.1 5.7 1.4 1 1 0 1 1 1 0 Striatin family Dicty_REP PF05086.7 EGG05885.1 - 7.9 4.0 9.0 8.5 3.9 6.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NTP_transferase PF00483.18 EGG05886.1 - 0.0046 16.3 0.0 0.0052 16.1 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase RicinB_lectin_2 PF14200.1 EGG05887.1 - 0.039 14.3 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like SNF2_N PF00176.18 EGG05888.1 - 8.6e-71 238.1 1.5 1.4e-70 237.4 1.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EGG05888.1 - 1.4e-42 145.0 16.1 3.4e-42 143.7 11.2 1.7 1 0 0 1 1 1 1 DNA-binding domain Helicase_C PF00271.26 EGG05888.1 - 4.2e-14 52.1 0.0 9.8e-14 50.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGG05888.1 - 2e-08 33.4 0.0 1.1e-05 24.4 0.0 3.0 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EGG05888.1 - 8.7e-06 25.6 0.0 3.8e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGG05888.1 - 0.0026 17.2 0.0 0.0077 15.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myosin_N PF02736.14 EGG05888.1 - 0.064 12.9 0.1 4.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain DnaJ PF00226.26 EGG05889.1 - 6.6e-10 38.5 0.0 2.9e-09 36.5 0.0 2.1 2 1 0 2 2 2 1 DnaJ domain DUF4131 PF13567.1 EGG05889.1 - 1.5 8.2 4.3 2.9 7.2 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Mito_carr PF00153.22 EGG05894.1 - 8.5e-43 143.9 1.0 1.8e-20 72.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Periviscerokin PF08259.6 EGG05894.1 - 0.052 13.5 0.8 0.3 11.2 0.5 2.4 1 0 0 1 1 1 0 Periviscerokinin family SNF2_N PF00176.18 EGG05895.1 - 3.1e-73 246.2 0.7 4.8e-73 245.5 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGG05895.1 - 6.1e-11 42.0 0.0 1.9e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EGG05895.1 - 0.00088 18.9 4.8 0.00088 18.9 3.3 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGG05895.1 - 0.056 13.4 6.1 0.84 9.7 4.7 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG05895.1 - 0.21 11.2 4.4 3.6 7.3 3.6 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGG05895.1 - 0.86 9.4 8.1 4.3 7.2 5.7 2.1 1 1 0 1 1 1 0 Ring finger domain UAA PF08449.6 EGG05896.1 - 8.6e-14 51.1 12.1 1.3e-13 50.5 8.4 1.2 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EGG05896.1 - 9.7e-10 37.9 0.7 1.4e-09 37.4 0.5 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EGG05896.1 - 8.2e-09 35.2 19.6 3.4e-06 26.7 5.2 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 EGG05896.1 - 2.1e-07 31.0 30.8 2.3e-05 24.4 5.1 3.7 3 1 1 4 4 4 2 EamA-like transporter family EmrE PF13536.1 EGG05896.1 - 5.7e-06 26.5 7.8 5.7e-06 26.5 5.4 3.5 2 1 1 3 3 3 1 Multidrug resistance efflux transporter WCOR413 PF05562.6 EGG05896.1 - 0.006 16.1 0.8 0.012 15.1 0.6 1.5 1 0 0 1 1 1 1 Cold acclimation protein WCOR413 Ferric_reduct PF01794.14 EGG05896.1 - 0.44 10.6 6.9 4.4 7.3 4.8 2.4 1 1 0 1 1 1 0 Ferric reductase like transmembrane component UPF0546 PF10639.4 EGG05896.1 - 2.3 8.0 10.1 0.065 13.0 1.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 GATA PF00320.22 EGG05897.1 - 7.4e-10 38.0 0.2 7.4e-10 38.0 0.2 2.7 3 0 0 3 3 3 1 GATA zinc finger bZIP_1 PF00170.16 EGG05898.1 - 0.012 15.5 0.3 0.022 14.6 0.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor Pox_A_type_inc PF04508.7 EGG05898.1 - 0.079 12.7 1.1 15 5.6 0.1 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Dscam_C PF12355.3 EGG05899.1 - 1.3 9.2 7.8 0.17 12.1 1.7 2.2 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal zf-CCHC PF00098.18 EGG05900.1 - 0.0051 16.6 2.5 0.0051 16.6 1.7 3.4 3 1 0 3 3 3 2 Zinc knuckle Rad50_zn_hook PF04423.9 EGG05900.1 - 0.011 15.1 0.5 0.011 15.1 0.3 2.6 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-CCHC_4 PF14392.1 EGG05900.1 - 0.031 13.9 6.8 0.63 9.7 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EGG05900.1 - 0.034 13.8 12.3 0.064 12.9 1.2 2.9 3 0 0 3 3 3 0 Zinc knuckle Coiled PF05710.7 EGG05900.1 - 0.051 14.0 0.2 0.098 13.1 0.1 1.4 1 0 0 1 1 1 0 Coiled coil zf-CCHC_2 PF13696.1 EGG05900.1 - 0.064 12.7 0.9 2.3 7.7 0.0 2.7 2 0 0 2 2 2 0 Zinc knuckle Mut7-C PF01927.11 EGG05900.1 - 0.67 9.9 3.4 11 5.9 1.6 2.2 2 0 0 2 2 2 0 Mut7-C RNAse domain zinc-ribbons_6 PF07191.7 EGG05900.1 - 3.1 7.6 12.3 7 6.5 0.4 3.2 3 0 0 3 3 3 0 zinc-ribbons Zn-ribbon_8 PF09723.5 EGG05900.1 - 5.9 6.9 9.1 16 5.5 0.3 3.4 3 0 0 3 3 3 0 Zinc ribbon domain DnaJ_CXXCXGXG PF00684.14 EGG05900.1 - 8.5 6.5 18.4 68 3.6 10.1 2.9 2 1 0 2 2 2 0 DnaJ central domain Plasmodium_HRP PF05403.6 EGG05901.1 - 2.5e-06 27.2 35.7 4.4e-05 23.1 14.0 2.0 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) DUF4573 PF15140.1 EGG05901.1 - 0.0019 17.8 9.1 0.019 14.5 2.6 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) Glutenin_hmw PF03157.8 EGG05901.1 - 0.082 11.1 0.4 0.095 10.9 0.3 1.0 1 0 0 1 1 1 0 High molecular weight glutenin subunit DUF2624 PF11116.3 EGG05901.1 - 0.13 12.7 1.1 9.7 6.7 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2624) Mob_synth_C PF06463.8 EGG05901.1 - 0.19 11.4 6.6 2.2 7.9 1.0 2.3 1 1 1 2 2 2 0 Molybdenum Cofactor Synthesis C Drc1-Sld2 PF11719.3 EGG05902.1 - 3.7e-19 69.1 14.6 3.7e-19 69.1 10.1 3.9 1 1 1 2 2 2 1 DNA replication and checkpoint protein RCC1 PF00415.13 EGG05903.1 - 3.7e-18 65.4 1.3 0.00026 21.1 0.0 7.0 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGG05903.1 - 0.0002 20.8 9.5 0.41 10.3 0.1 5.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.27 EGG05904.1 - 3.8e-32 108.9 17.0 2.1e-09 36.8 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.7 EGG05904.1 - 9.1e-19 67.2 0.0 1.6e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain WHIM1 PF15612.1 EGG05905.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Carbpep_Y_N PF05388.6 EGG05905.1 - 0.11 12.7 1.3 0.31 11.2 0.2 2.2 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide HSP20 PF00011.16 EGG05906.1 - 6.7e-14 51.5 0.2 7.1e-14 51.5 0.2 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 EGG05906.1 - 0.042 13.4 0.1 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) PLDc PF00614.17 EGG05908.1 - 8.6e-15 53.9 0.2 4.2e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EGG05908.1 - 2.9e-12 46.4 0.0 1.9e-07 30.8 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EGG05908.1 - 4.4e-12 45.7 2.9 6.2e-11 42.0 0.1 3.0 3 0 0 3 3 3 1 PX domain PH PF00169.24 EGG05908.1 - 3.8e-07 30.2 0.1 1.1e-06 28.8 0.1 1.8 1 0 0 1 1 1 1 PH domain Epimerase PF01370.16 EGG05909.1 - 1.4e-68 230.8 0.1 1.8e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGG05909.1 - 1.8e-08 33.6 0.0 4.3e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGG05909.1 - 0.00041 19.3 0.0 0.00066 18.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EGG05909.1 - 0.00047 19.4 0.0 0.00074 18.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGG05909.1 - 0.00067 19.7 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase_Csub PF13950.1 EGG05909.1 - 0.078 12.9 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Trypan_PARP PF05887.6 EGG05910.1 - 0.58 9.9 19.7 0.75 9.6 13.5 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1180 PF06679.7 EGG05910.1 - 2.5 7.9 6.3 3.6 7.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Sec39 PF08314.6 EGG05911.1 - 8.1e-63 212.4 0.6 1.4e-62 211.7 0.4 1.3 1 0 0 1 1 1 1 Secretory pathway protein Sec39 LRR_6 PF13516.1 EGG05912.1 - 1.8e-11 42.8 26.0 0.0073 16.2 0.0 10.0 10 2 1 11 11 11 4 Leucine Rich repeat LRR_4 PF12799.2 EGG05912.1 - 0.00029 20.3 39.3 0.087 12.4 1.5 8.0 6 3 4 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG05912.1 - 0.0011 18.6 24.9 0.064 13.0 0.4 6.3 6 0 0 6 6 6 3 Leucine rich repeat LRR_1 PF00560.28 EGG05912.1 - 0.024 14.5 17.6 0.55 10.4 0.0 7.7 7 2 1 8 8 8 0 Leucine Rich Repeat SUR7 PF06687.7 EGG05913.1 - 1.7e-22 80.0 16.3 2.1e-22 79.7 11.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family HR_lesion PF05514.6 EGG05913.1 - 0.011 15.5 0.3 0.019 14.7 0.2 1.3 1 0 0 1 1 1 0 HR-like lesion-inducing MpPF26 PF07666.6 EGG05913.1 - 4.4 7.2 6.8 1.2 9.0 0.7 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 Acetyltransf_13 PF13880.1 EGG05914.1 - 1.3e-16 60.0 0.0 2.3e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_1 PF00583.19 EGG05914.1 - 0.00053 19.9 0.0 0.00085 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGG05914.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-CCCH PF00642.19 EGG05915.1 - 1.4e-14 53.3 24.2 1.7e-05 24.3 0.6 4.1 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGG05915.1 - 0.01 15.8 2.0 0.01 15.8 1.4 4.6 4 1 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type UPF1_Zn_bind PF09416.5 EGG05915.1 - 0.094 12.2 0.3 0.094 12.2 0.2 1.6 1 1 1 2 2 2 0 RNA helicase (UPF2 interacting domain) zf-HIT PF04438.11 EGG05916.1 - 0.025 14.2 1.3 0.047 13.3 0.9 1.4 1 0 0 1 1 1 0 HIT zinc finger UxaC PF02614.9 EGG05919.1 - 0.047 12.3 0.0 0.078 11.5 0.0 1.3 1 0 0 1 1 1 0 Glucuronate isomerase Aldose_epim PF01263.15 EGG05921.1 - 5.7e-17 61.7 0.0 2.5e-08 33.3 0.0 2.9 2 1 0 2 2 2 2 Aldose 1-epimerase Lactonase PF10282.4 EGG05922.1 - 4.1e-78 262.8 0.1 4.9e-78 262.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.7 EGG05922.1 - 0.0046 16.5 3.9 0.67 9.6 0.0 4.2 4 1 1 5 5 5 2 WD40-like Beta Propeller Repeat UCR_hinge PF02320.11 EGG05924.1 - 7.1e-20 70.7 4.9 1.3e-19 69.8 3.4 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 EGG05924.1 - 0.016 14.8 0.4 0.016 14.7 0.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Ribosomal_60s PF00428.14 EGG05924.1 - 0.027 14.8 5.2 0.042 14.2 3.6 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-TAZ PF02135.11 EGG05924.1 - 0.049 13.6 4.2 0.07 13.1 2.9 1.3 1 0 0 1 1 1 0 TAZ zinc finger DUF4611 PF15387.1 EGG05924.1 - 0.17 12.0 3.5 0.16 12.1 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Fmp27 PF10344.4 EGG05924.1 - 0.57 7.7 2.1 0.7 7.5 1.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 CHCH PF06747.8 EGG05924.1 - 2 8.4 6.8 11 6.0 0.8 2.3 1 1 1 2 2 2 0 CHCH domain Brevenin PF03032.10 EGG05924.1 - 3.2 7.6 7.2 7.5 6.4 5.0 1.6 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family F-box PF00646.28 EGG05926.1 - 0.088 12.4 0.7 0.19 11.3 0.5 1.6 1 0 0 1 1 1 0 F-box domain bZIP_1 PF00170.16 EGG05927.1 - 1.7e-05 24.6 3.4 3.6e-05 23.6 2.1 1.9 1 1 0 1 1 1 1 bZIP transcription factor Cas_Cas4 PF01930.12 EGG05927.1 - 0.051 13.4 5.2 0.072 13.0 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF83 P4Ha_N PF08336.6 EGG05927.1 - 4.8 7.0 8.4 5.8 6.7 4.4 2.1 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region MCLC PF05934.6 EGG05927.1 - 5.7 5.1 6.9 4.6 5.4 3.9 1.3 1 1 0 1 1 1 0 Mid-1-related chloride channel (MCLC) zf-RING_2 PF13639.1 EGG05928.1 - 3.8e-05 23.4 1.5 8.4e-05 22.3 1.1 1.6 1 0 0 1 1 1 1 Ring finger domain Lung_7-TM_R PF06814.8 EGG05929.1 - 3.7e-64 216.4 16.3 3.7e-64 216.4 11.3 1.8 2 0 0 2 2 2 1 Lung seven transmembrane receptor Orbi_NS3 PF01616.11 EGG05929.1 - 0.006 15.5 0.2 0.014 14.3 0.1 1.6 1 0 0 1 1 1 1 Orbivirus NS3 PepSY_TM_2 PF13703.1 EGG05929.1 - 0.016 15.3 3.6 0.016 15.3 2.5 4.1 3 2 1 4 4 4 0 PepSY-associated TM helix DUF4245 PF14030.1 EGG05929.1 - 0.096 12.4 0.4 1.4 8.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4245) DUF3099 PF11298.3 EGG05929.1 - 1 9.1 11.5 0.39 10.4 0.5 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3099) DUF2419 PF10343.4 EGG05931.1 - 2.1e-13 50.2 0.0 3.8e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) PSCyt3 PF07627.6 EGG05931.1 - 0.042 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) SseB_C PF14581.1 EGG05931.1 - 0.051 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 SseB protein C-terminal domain Arm PF00514.18 EGG05931.1 - 0.062 13.1 0.4 0.2 11.5 0.3 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat DUF1590 PF07629.6 EGG05931.1 - 6.7 6.3 9.2 0.92 9.1 2.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1590) AMP-binding PF00501.23 EGG05932.1 - 1.5e-25 89.4 0.0 3.9e-24 84.8 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme GBP_PSP PF02425.10 EGG05932.1 - 0.0032 16.9 0.2 0.0032 16.9 0.1 2.0 2 0 0 2 2 2 1 Paralytic/GBP/PSP peptide PP-binding PF00550.20 EGG05932.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site HMD PF03201.11 EGG05932.1 - 0.02 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase AMP-binding PF00501.23 EGG05935.1 - 6.5e-25 87.3 0.0 2.9e-23 81.9 0.0 2.4 2 1 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.20 EGG05935.1 - 0.013 15.7 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site GBP_PSP PF02425.10 EGG05935.1 - 0.02 14.4 0.2 0.083 12.4 0.1 2.0 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide HMD PF03201.11 EGG05935.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF202 PF02656.10 EGG05936.1 - 2.6e-10 40.3 4.3 6.1e-10 39.1 3.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF202) DUF1244 PF06844.6 EGG05938.1 - 0.096 12.5 1.0 0.15 11.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) Ribosomal_L22 PF00237.14 EGG05939.1 - 7.1e-18 64.4 0.2 1.2e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Pox_I1 PF03289.8 EGG05941.1 - 0.0084 14.9 0.2 0.014 14.2 0.2 1.3 1 0 0 1 1 1 1 Poxvirus protein I1 Pet191_N PF10203.4 EGG05942.1 - 2.6e-25 88.2 1.0 2.9e-25 88.0 0.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COX16 PF14138.1 EGG05943.1 - 7.3e-13 48.4 5.0 1.1e-11 44.6 3.4 2.1 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DUF1012 PF06241.7 EGG05944.1 - 0.00083 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1012) AATF-Che1 PF13339.1 EGG05944.1 - 0.0095 16.0 2.5 1.1 9.4 0.4 2.4 1 1 1 2 2 2 2 Apoptosis antagonizing transcription factor DUF3362 PF11842.3 EGG05944.1 - 0.61 9.9 3.5 0.96 9.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3362) Sec20 PF03908.8 EGG05944.1 - 2.2 8.0 5.1 8.8 6.1 0.3 2.7 2 1 1 3 3 3 0 Sec20 SurE PF01975.12 EGG05945.1 - 5e-36 123.8 0.0 7.1e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Methyltransf_4 PF02390.12 EGG05946.1 - 6.2e-49 165.7 0.1 7.2e-37 126.3 0.1 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EGG05946.1 - 8.1e-05 23.1 0.0 0.00021 21.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG05946.1 - 0.0044 17.0 0.0 0.0079 16.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EGG05946.1 - 0.0078 15.5 0.0 0.028 13.7 0.0 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.1 EGG05946.1 - 0.042 14.2 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EGG05946.1 - 0.046 13.0 0.0 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EGG05946.1 - 0.13 12.7 0.0 0.43 11.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Catalase PF00199.14 EGG05948.1 - 2.3e-80 270.1 0.0 2.5e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 Catalase NAM-associated PF14303.1 EGG05949.1 - 1.8e-05 25.1 1.5 3.8e-05 24.0 1.0 1.6 1 1 0 1 1 1 1 No apical meristem-associated C-terminal domain Catalase PF00199.14 EGG05950.1 - 5.5e-77 259.0 0.0 1.2e-75 254.5 0.0 2.0 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGG05950.1 - 3.8e-13 49.0 0.0 9.4e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive RRM_1 PF00076.17 EGG05951.1 - 2.4e-19 68.6 0.0 2.7e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG05951.1 - 6.8e-17 61.2 0.0 7.7e-17 61.0 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG05951.1 - 3.4e-14 52.4 0.0 4.5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 EGG05952.1 - 1.3e-61 206.7 0.5 1.5e-61 206.5 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG05952.1 - 2.4e-20 73.2 0.0 3.6e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG05952.1 - 1.3e-13 50.5 0.0 1.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGG05952.1 - 2.3e-06 27.5 0.0 3e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGG05952.1 - 6.8e-06 25.6 0.0 1.3e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGG05952.1 - 7.5e-06 25.2 0.1 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EGG05952.1 - 0.0031 17.5 0.9 0.012 15.6 0.5 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGG05952.1 - 0.0035 17.4 0.1 0.071 13.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain DUF2868 PF11067.3 EGG05952.1 - 0.012 14.7 0.2 0.014 14.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) G-alpha PF00503.15 EGG05952.1 - 0.017 13.8 0.8 6.2 5.4 0.0 2.8 1 1 2 3 3 3 0 G-protein alpha subunit DUF258 PF03193.11 EGG05952.1 - 0.023 13.8 0.1 0.097 11.8 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function, DUF258 KaiC PF06745.8 EGG05952.1 - 0.037 13.1 0.3 4.9 6.2 0.1 2.1 2 0 0 2 2 2 0 KaiC Septin PF00735.13 EGG05952.1 - 0.037 13.0 0.1 0.078 11.9 0.0 1.5 2 0 0 2 2 2 0 Septin BRCA2 PF00634.13 EGG05952.1 - 0.11 11.8 0.4 0.23 10.7 0.3 1.5 1 0 0 1 1 1 0 BRCA2 repeat RRM_1 PF00076.17 EGG05953.1 - 3.3e-16 58.6 0.0 4.5e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG05953.1 - 4.3e-15 55.4 0.0 6e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG05953.1 - 2.1e-11 43.4 0.0 2.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAFH PF07531.9 EGG05954.1 - 0.075 12.6 0.2 5.4 6.7 0.0 2.8 3 0 0 3 3 3 0 NHR1 homology to TAF SpoVIF PF14069.1 EGG05954.1 - 0.098 12.3 0.1 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Stage VI sporulation protein F Esterase PF00756.15 EGG05957.1 - 2.8e-45 154.7 0.0 3.2e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EGG05957.1 - 4.8e-05 23.1 0.0 6.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGG05957.1 - 0.0029 16.8 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EGG05957.1 - 0.025 14.1 0.1 0.055 13.0 0.0 1.7 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGG05957.1 - 0.031 14.1 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGG05957.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Zn-ribbon_8 PF09723.5 EGG05958.1 - 0.025 14.5 5.2 0.18 11.8 0.6 3.2 3 0 0 3 3 3 0 Zinc ribbon domain FAM209 PF15206.1 EGG05958.1 - 0.15 11.9 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 FAM209 family PAS_9 PF13426.1 EGG05959.1 - 1.1e-14 54.6 0.0 1.5e-12 47.8 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EGG05959.1 - 0.00028 20.8 0.0 0.0081 16.1 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 EGG05959.1 - 0.0073 16.0 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 EGG05959.1 - 0.11 12.3 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 PAS domain Polysacc_deac_1 PF01522.16 EGG05960.1 - 7.3e-07 28.8 0.2 2.5e-06 27.1 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase Nucleos_tra2_C PF07662.8 EGG05960.1 - 0.044 13.2 0.1 0.078 12.4 0.1 1.3 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus Phage_int_SAM_1 PF02899.12 EGG05961.1 - 0.0025 17.9 0.0 0.023 14.8 0.0 2.1 1 1 1 2 2 2 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 EGG05961.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.6 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Rhodanese PF00581.15 EGG05962.1 - 8.2e-11 42.2 0.0 8.8e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain T2SM PF04612.7 EGG05962.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M ATP-synt_F PF01990.12 EGG05963.1 - 8e-29 99.8 0.1 9.1e-29 99.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Acyl-CoA_dh_1 PF00441.19 EGG05964.1 - 1.1e-42 145.6 0.1 1.6e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGG05964.1 - 1.5e-31 109.3 0.0 2.9e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGG05964.1 - 9.1e-14 51.8 0.0 1.2e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGG05964.1 - 1.8e-13 49.7 0.0 4.2e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EGG05964.1 - 0.046 14.0 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Acyltransferase PF01553.16 EGG05965.1 - 1.2e-14 53.8 0.0 2.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NMT_C PF02799.10 EGG05965.1 - 0.0065 15.8 0.2 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DDDD PF10161.4 EGG05966.1 - 2.7 7.7 6.5 4.7 6.9 4.5 1.4 1 0 0 1 1 1 0 Putative mitochondrial precursor protein RRM_1 PF00076.17 EGG05967.1 - 2.5e-05 23.8 0.0 0.00024 20.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG05967.1 - 0.00013 21.9 0.0 0.00041 20.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 EGG05970.1 - 1.1e-23 84.0 0.0 1.4e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG05970.1 - 5.2e-15 55.8 0.1 6.5e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG05970.1 - 2.3e-09 37.1 0.2 4.5e-09 36.2 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGG05970.1 - 5.6e-07 29.2 0.0 1.2e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGG05970.1 - 0.00025 21.1 0.1 0.003 17.6 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding YjeF_N PF03853.10 EGG05970.1 - 0.0014 18.3 0.1 0.0024 17.5 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus NmrA PF05368.8 EGG05970.1 - 0.0046 16.2 0.0 0.0086 15.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 EGG05970.1 - 0.017 14.8 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EGG05970.1 - 0.03 13.2 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EGG05970.1 - 0.062 12.9 0.1 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1462 PF07315.6 EGG05970.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) 3Beta_HSD PF01073.14 EGG05970.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Bcl-2 PF00452.14 EGG05970.1 - 0.12 12.5 0.8 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family RVT_3 PF13456.1 EGG05974.1 - 4.2e-06 26.4 0.0 8.6e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like RE_ApaLI PF09499.5 EGG05974.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease DEAD PF00270.24 EGG05975.1 - 5.3e-05 22.7 0.0 9.1e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG05975.1 - 0.00018 21.2 0.1 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC2_membrane_5 PF13346.1 EGG05976.1 - 0.26 10.5 3.9 0.25 10.6 1.5 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF1980 PF09323.5 EGG05976.1 - 1.7 8.3 3.7 0.46 10.1 0.3 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) Peptidase_C93 PF06035.6 EGG05977.1 - 0.00014 21.3 5.8 0.067 12.6 0.0 3.9 1 1 3 4 4 4 1 Bacterial transglutaminase-like cysteine proteinase BTLCP ABC_transp_aux PF09822.4 EGG05977.1 - 0.00027 20.4 12.0 0.0084 15.6 4.0 2.2 1 1 1 2 2 2 2 ABC-type uncharacterized transport system ApbA_C PF08546.6 EGG05977.1 - 0.00029 20.8 2.0 2 8.4 0.0 3.7 1 1 2 4 4 4 2 Ketopantoate reductase PanE/ApbA C terminal Filament PF00038.16 EGG05977.1 - 0.0088 15.5 10.6 0.75 9.2 5.5 2.9 1 1 1 3 3 3 2 Intermediate filament protein ATP_bind_4 PF01902.12 EGG05977.1 - 0.012 14.9 5.4 0.82 8.9 0.2 2.9 1 1 2 3 3 3 0 ATP-binding region TcdB_toxin_midN PF12256.3 EGG05977.1 - 0.017 14.5 11.7 7.2 6.0 0.1 4.7 1 1 4 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region CPSase_L_D2 PF02786.12 EGG05977.1 - 0.034 13.4 2.4 1.6 7.9 0.3 2.2 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PAPA-1 PF04795.7 EGG05977.1 - 0.039 14.6 8.0 0.91 10.2 1.7 2.7 1 1 2 3 3 3 0 PAPA-1-like conserved region BAG PF02179.11 EGG05977.1 - 0.064 13.3 4.3 14 5.9 0.3 3.1 3 0 0 3 3 3 0 BAG domain TRL PF13146.1 EGG05977.1 - 0.29 11.1 4.1 14 5.7 0.0 4.1 5 0 0 5 5 5 0 TRL-like protein family Scm3 PF10384.4 EGG05977.1 - 0.38 10.2 5.5 98 2.5 0.0 4.2 4 0 0 4 4 4 0 Centromere protein Scm3 XkdW PF09636.5 EGG05977.1 - 2.5 8.0 13.0 13 5.7 0.2 5.0 1 1 2 4 4 4 0 XkdW protein DUF2682 PF10909.3 EGG05977.1 - 2.6 8.3 14.6 5.3 7.3 0.9 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF2682) TrbM PF07424.6 EGG05977.1 - 3.7 7.5 14.6 2.3 8.1 2.5 2.9 1 1 2 3 3 3 0 TrbM Methyltransf_26 PF13659.1 EGG05978.1 - 2.1e-05 24.5 0.0 0.0007 19.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EGG05978.1 - 0.00035 20.2 0.0 0.00061 19.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DUF3341 PF11821.3 EGG05978.1 - 0.0085 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3341) ETF_QO PF05187.8 EGG05979.1 - 1.4e-37 128.0 0.0 3.1e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EGG05979.1 - 2.6e-09 36.4 0.0 1.9e-05 23.7 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGG05979.1 - 1.1e-06 28.6 0.0 2.9e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGG05979.1 - 2.2e-06 26.8 0.0 0.00027 19.9 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EGG05979.1 - 5.5e-05 22.3 0.0 0.00051 19.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EGG05979.1 - 7.7e-05 22.6 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGG05979.1 - 0.00011 20.8 0.2 0.00017 20.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EGG05979.1 - 0.00013 22.0 0.0 0.00035 20.7 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGG05979.1 - 0.00049 19.2 0.0 0.0013 17.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EGG05979.1 - 0.00059 19.6 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EGG05979.1 - 0.00076 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EGG05979.1 - 0.0064 15.6 0.0 0.0094 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer4_7 PF12838.2 EGG05979.1 - 0.027 14.8 0.2 0.068 13.5 0.1 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pyr_redox PF00070.22 EGG05979.1 - 0.055 13.8 0.0 2 8.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGG05979.1 - 0.12 11.2 0.2 0.19 10.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EGG05979.1 - 0.17 10.4 0.1 0.27 9.7 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Fer4_2 PF12797.2 EGG05979.1 - 3.9 7.5 5.6 0.43 10.6 0.6 2.0 2 0 0 2 2 1 0 4Fe-4S binding domain Vps51 PF08700.6 EGG05981.1 - 4.8e-08 32.7 0.1 5.3e-07 29.3 0.1 2.8 1 1 0 1 1 1 1 Vps51/Vps67 Arf PF00025.16 EGG05982.1 - 4.4e-66 221.4 0.0 4.9e-66 221.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGG05982.1 - 8.2e-10 37.9 0.1 1.9e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EGG05982.1 - 1.2e-08 34.3 0.0 1.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGG05982.1 - 1.3e-07 31.5 0.0 3.8e-07 30.0 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EGG05982.1 - 8e-07 29.5 0.0 1.1e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EGG05982.1 - 2.5e-06 26.9 0.0 3.2e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGG05982.1 - 2.2e-05 23.7 0.0 2.2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGG05982.1 - 0.019 14.4 0.0 0.05 13.1 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EGG05982.1 - 0.032 13.6 0.0 0.93 8.8 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain tRNA-synt_2b PF00587.20 EGG05983.1 - 7.3e-33 113.5 0.1 1.4e-32 112.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGG05983.1 - 2.9e-19 69.0 2.5 5.2e-19 68.2 1.7 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain MAD PF05557.8 EGG05983.1 - 0.06 11.4 1.5 0.087 10.9 1.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Med9 PF07544.8 EGG05983.1 - 0.076 12.7 0.5 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.7 EGG05983.1 - 0.11 12.2 3.1 0.19 11.4 2.2 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 EGG05983.1 - 3.6 7.3 9.0 25 4.6 4.9 2.6 2 1 1 3 3 3 0 Prefoldin subunit WD40 PF00400.27 EGG05984.1 - 3.2e-23 80.7 8.2 0.00014 21.5 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGG05984.1 - 6.2e-05 22.7 0.0 0.37 10.4 0.0 3.4 1 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EGG05984.1 - 0.0033 15.3 0.0 0.18 9.5 0.0 2.2 1 1 1 2 2 2 2 IKI3 family MIP PF00230.15 EGG05985.1 - 2.4e-22 79.5 8.0 3.3e-22 79.0 5.6 1.3 1 0 0 1 1 1 1 Major intrinsic protein Toxin_47 PF15527.1 EGG05985.1 - 2.2e-05 24.2 0.2 0.0031 17.2 0.0 2.6 1 1 0 2 2 2 2 Putative toxin 47 ImcF-related_N PF14331.1 EGG05989.1 - 0.029 13.2 0.8 0.042 12.7 0.6 1.3 1 0 0 1 1 1 0 ImcF-related N-terminal domain Tropomyosin_1 PF12718.2 EGG05989.1 - 0.2 11.5 11.7 0.64 9.8 8.1 1.8 1 1 0 1 1 1 0 Tropomyosin like IncA PF04156.9 EGG05989.1 - 0.21 11.1 7.6 0.35 10.4 5.3 1.3 1 0 0 1 1 1 0 IncA protein Alpha_kinase PF02816.13 EGG05996.1 - 0.00063 19.4 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Alpha-kinase family Hydrolase_like2 PF13246.1 EGG06000.1 - 2e-11 43.6 0.0 6.4e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EGG06000.1 - 0.03 13.3 0.6 0.083 11.9 0.5 1.6 1 1 1 2 2 2 0 E1-E2 ATPase Elf1 PF05129.8 EGG06001.1 - 1.4e-24 85.5 1.1 2.3e-24 84.8 0.7 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Glyco_hydro_31 PF01055.21 EGG06001.1 - 0.013 14.3 0.1 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 zf-CHY PF05495.7 EGG06001.1 - 0.41 10.8 3.9 0.13 12.4 0.6 1.7 2 0 0 2 2 2 0 CHY zinc finger Tnp_zf-ribbon_2 PF13842.1 EGG06001.1 - 0.59 10.5 2.8 1.3 9.5 1.9 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-RING_UBOX PF13445.1 EGG06002.1 - 1.2e-06 28.1 1.2 2.4e-06 27.1 0.1 2.2 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EGG06002.1 - 2e-06 27.3 7.3 6.3e-06 25.8 1.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGG06002.1 - 7.5e-06 25.6 1.7 7.5e-06 25.6 1.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGG06002.1 - 1.4e-05 25.0 2.1 1.4e-05 25.0 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGG06002.1 - 2.4e-05 24.1 5.4 4.2e-05 23.3 1.2 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EGG06002.1 - 0.00021 20.8 2.5 0.00021 20.8 1.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG06002.1 - 0.00039 20.0 4.5 0.0026 17.4 0.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) IncA PF04156.9 EGG06002.1 - 0.016 14.8 3.2 0.022 14.3 2.2 1.2 1 0 0 1 1 1 0 IncA protein zf-Nse PF11789.3 EGG06002.1 - 0.032 13.7 0.5 0.13 11.7 0.4 2.1 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.16 EGG06002.1 - 0.048 13.5 0.9 0.2 11.5 0.6 2.1 1 1 0 1 1 1 0 FYVE zinc finger HlyD PF00529.15 EGG06002.1 - 0.064 12.5 5.4 0.085 12.1 3.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Cluap1 PF10234.4 EGG06002.1 - 0.092 11.9 1.5 0.13 11.4 1.1 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF1409 PF07197.7 EGG06002.1 - 0.16 12.0 1.9 0.48 10.5 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1409) ASD2 PF08687.6 EGG06002.1 - 0.45 9.7 5.0 0.62 9.3 3.5 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 zf-C2H2 PF00096.21 EGG06002.1 - 0.92 9.9 5.1 1 9.8 0.4 3.1 2 1 1 3 3 3 0 Zinc finger, C2H2 type DEAD PF00270.24 EGG06003.1 - 1.9e-37 128.3 0.1 4e-37 127.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG06003.1 - 2.5e-24 84.9 0.0 6.5e-24 83.6 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG06003.1 - 4.9e-05 23.2 0.0 8.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EGG06003.1 - 0.015 14.3 0.0 0.036 13.1 0.0 1.7 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EGG06005.1 - 8.6e-46 155.5 0.0 1.9e-45 154.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGG06005.1 - 2.4e-22 78.2 0.2 4.9e-22 77.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGG06005.1 - 2.3e-19 69.0 0.0 6e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EGG06005.1 - 0.015 15.2 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain 2OG-FeII_Oxy_2 PF13532.1 EGG06007.1 - 0.1 12.3 0.3 0.22 11.3 0.1 1.5 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily Ferric_reduct PF01794.14 EGG06008.1 - 1.4e-05 25.1 6.2 1.9e-05 24.7 4.3 1.3 1 1 0 1 1 1 1 Ferric reductase like transmembrane component Alpha_kinase PF02816.13 EGG06010.1 - 2.3e-08 33.9 3.7 3e-08 33.5 0.0 2.5 3 0 0 3 3 3 1 Alpha-kinase family UPF0061 PF02696.9 EGG06011.1 - 2.6e-92 309.6 0.0 6.4e-92 308.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family p450 PF00067.17 EGG06012.1 - 5.2e-83 279.1 0.0 6.4e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.17 EGG06013.1 - 4.8e-71 240.0 0.1 7e-71 239.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase ABC_tran PF00005.22 EGG06014.1 - 2e-33 115.5 0.0 3.7e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGG06014.1 - 1.2e-27 97.0 10.6 1.6e-27 96.5 7.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EGG06014.1 - 4.1e-07 30.2 0.3 0.00014 21.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EGG06014.1 - 8.8e-06 25.1 0.2 0.0051 16.0 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EGG06014.1 - 0.00075 19.6 0.0 0.0036 17.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGG06014.1 - 0.00097 19.1 0.3 0.0094 15.9 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.24 EGG06014.1 - 0.0014 18.8 0.0 0.0081 16.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGG06014.1 - 0.0022 17.8 0.5 0.082 12.8 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_29 PF13555.1 EGG06014.1 - 0.0061 16.0 0.0 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGG06014.1 - 0.013 16.3 0.9 0.062 14.1 0.2 2.3 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EGG06014.1 - 0.02 14.7 0.3 0.22 11.4 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 EGG06014.1 - 0.042 12.4 0.3 0.077 11.5 0.0 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF258 PF03193.11 EGG06014.1 - 0.047 12.8 0.0 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EGG06014.1 - 0.099 12.9 0.1 1 9.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EGG06014.1 - 0.12 11.7 0.0 0.38 10.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGG06014.1 - 0.18 12.1 2.0 0.48 10.7 0.5 2.3 2 1 0 2 2 2 0 AAA domain SOXp PF12336.3 EGG06015.1 - 0.21 12.2 1.3 0.58 10.8 0.9 1.8 1 0 0 1 1 1 0 SOX transcription factor Pkinase PF00069.20 EGG06016.1 - 1.1e-62 211.5 0.0 1.2e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG06016.1 - 1e-45 155.8 0.0 1.2e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG06016.1 - 1.4e-06 27.5 0.0 3e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EGG06016.1 - 0.0082 15.0 0.2 0.086 11.6 0.0 2.0 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.18 EGG06016.1 - 0.071 12.8 0.0 1.7 8.3 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EGG06016.1 - 0.088 11.8 0.0 0.19 10.7 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec10 PF07393.6 EGG06017.1 - 4.1e-93 312.8 0.0 1e-90 304.9 0.0 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EGG06017.1 - 1.6e-08 34.1 0.4 4.8e-08 32.6 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGG06017.1 - 6.1e-07 28.9 3.0 6.1e-07 28.9 2.1 2.2 2 0 0 2 2 2 1 F-box domain adh_short PF00106.20 EGG06018.1 - 0.019 14.9 0.0 0.019 14.9 0.0 1.0 1 0 0 1 1 1 0 short chain dehydrogenase MBOAT_2 PF13813.1 EGG06019.1 - 8.1e-16 57.8 2.4 2.8e-15 56.1 1.7 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Ubie_methyltran PF01209.13 EGG06020.1 - 2.1e-75 252.8 0.0 2.6e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EGG06020.1 - 7.3e-11 42.4 0.0 1.2e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG06020.1 - 1.9e-10 40.5 0.0 2.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG06020.1 - 1.4e-08 35.1 0.0 2.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG06020.1 - 1.2e-07 31.9 0.0 2.2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG06020.1 - 1.7e-05 24.5 0.0 2.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG06020.1 - 6.1e-05 23.5 0.0 0.00011 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EGG06020.1 - 0.0065 16.1 0.0 0.082 12.5 0.0 2.3 2 0 0 2 2 2 1 Hypothetical methyltransferase LRR_1 PF00560.28 EGG06021.1 - 0.00072 19.2 0.0 0.21 11.7 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_8 PF13855.1 EGG06021.1 - 0.0062 16.2 0.0 0.16 11.7 0.0 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EGG06021.1 - 0.021 14.4 0.0 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Spo7 PF03907.8 EGG06023.1 - 6.7e-18 65.0 3.9 3.1e-17 62.8 0.8 2.0 2 0 0 2 2 2 1 Spo7-like protein Tmemb_18A PF09771.4 EGG06023.1 - 0.016 15.1 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 188 DUF1443 PF07280.6 EGG06023.1 - 4.8 6.8 6.4 1.6 8.3 1.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1443) SMI1_KNR4 PF09346.5 EGG06025.1 - 1.2e-08 34.9 2.8 5.8e-05 23.1 0.0 2.8 3 0 0 3 3 3 2 SMI1 / KNR4 family (SUKH-1) Proteasome PF00227.21 EGG06026.1 - 3.5e-53 179.7 0.1 6.8e-53 178.7 0.0 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 EGG06026.1 - 1.1e-14 53.3 0.2 2.1e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nucleoside_tran PF01733.13 EGG06028.1 - 1.4e-32 113.0 8.4 2.2e-32 112.4 5.9 1.2 1 0 0 1 1 1 1 Nucleoside transporter CTV_P6 PF06706.6 EGG06028.1 - 0.41 10.1 4.0 4.6 6.7 0.2 2.5 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Aminotran_1_2 PF00155.16 EGG06029.1 - 1.9e-43 148.8 0.0 2.8e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGG06029.1 - 0.0045 15.3 0.0 0.0076 14.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 EGG06029.1 - 0.005 15.4 0.0 0.017 13.7 0.0 1.9 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain HK PF02110.10 EGG06030.1 - 3.2e-73 245.9 3.1 1.6e-71 240.3 2.2 2.1 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EGG06030.1 - 5.6e-51 172.2 0.1 1.3e-43 148.2 0.0 3.6 2 1 1 3 3 3 2 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 EGG06030.1 - 0.0023 17.1 0.6 0.005 16.0 0.4 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.12 EGG06030.1 - 0.042 13.1 0.2 0.076 12.2 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate kinase MT PF12777.2 EGG06031.1 - 0.21 10.2 0.2 0.42 9.3 0.1 1.4 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor SlyX PF04102.7 EGG06031.1 - 0.39 11.1 6.9 0.88 9.9 2.1 2.7 2 0 0 2 2 2 0 SlyX Pro_CA PF00484.14 EGG06032.1 - 2.8e-33 115.0 0.0 3.2e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Carbonic anhydrase DUF2147 PF09917.4 EGG06032.1 - 0.0059 16.8 0.0 0.0083 16.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2147) OTCace_N PF02729.16 EGG06032.1 - 0.025 14.2 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF2235 PF09994.4 EGG06034.1 - 3.9e-46 157.6 0.0 2.1e-45 155.2 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) AAA_13 PF13166.1 EGG06035.1 - 0.08 11.3 37.3 0.051 12.0 4.7 3.0 2 1 1 3 3 3 0 AAA domain UPF0184 PF03670.8 EGG06035.1 - 0.082 13.0 5.2 0.29 11.3 1.9 3.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) O-FucT PF10250.4 EGG06036.1 - 7.9e-10 38.3 0.0 1.1e-08 34.6 0.0 2.3 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase DUF3160 PF11369.3 EGG06038.1 - 0.0061 14.9 0.1 0.008 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3160) CENP-B_dimeris PF09026.5 EGG06038.1 - 0.045 13.9 2.1 0.084 13.1 1.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Annexin PF00191.15 EGG06039.1 - 0.034 14.0 0.1 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 Annexin UQ_con PF00179.21 EGG06041.1 - 2.5e-17 62.5 0.0 3.7e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.20 EGG06042.1 - 2.5e-69 233.3 0.0 3.1e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG06042.1 - 1.3e-34 119.4 0.0 1.7e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG06042.1 - 0.051 12.5 0.0 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 EGG06042.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-UBP PF02148.14 EGG06045.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein TruB_C PF09142.6 EGG06045.1 - 0.32 10.6 2.4 0.6 9.8 0.9 2.1 1 1 1 2 2 2 0 tRNA Pseudouridine synthase II, C terminal SF-assemblin PF06705.6 EGG06046.1 - 0.021 13.9 0.6 0.021 13.9 0.4 1.6 2 0 0 2 2 2 0 SF-assemblin/beta giardin Apolipoprotein PF01442.13 EGG06046.1 - 0.077 12.4 2.3 0.14 11.6 0.2 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EGG06046.1 - 0.096 13.0 3.9 0.51 10.7 0.2 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 EGG06046.1 - 0.12 12.2 1.5 0.28 10.9 1.0 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF1G PF00647.14 EGG06047.1 - 8.1e-35 118.7 0.1 2e-34 117.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EGG06047.1 - 4.4e-11 42.6 0.0 1.3e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGG06047.1 - 1.7e-10 40.6 0.7 3.8e-10 39.5 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGG06047.1 - 2.4e-09 37.2 0.0 5.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGG06047.1 - 1e-08 35.2 0.0 2.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGG06047.1 - 0.00051 20.4 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGG06047.1 - 0.033 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain OAD_gamma PF04277.8 EGG06047.1 - 1.1 9.7 3.0 2.2 8.7 2.1 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain zf-C3HC4_3 PF13920.1 EGG06048.1 - 0.29 10.8 1.3 1.6 8.4 0.9 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cofilin_ADF PF00241.15 EGG06050.1 - 5.3e-24 84.5 0.0 5e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein CAP PF00188.21 EGG06051.1 - 4e-14 53.1 0.5 9.1e-14 52.0 0.1 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF3430 PF11912.3 EGG06051.1 - 0.035 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) CAP PF00188.21 EGG06052.1 - 6.2e-13 49.3 1.0 1.6e-12 48.0 0.7 1.7 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 EGG06053.1 - 7.1e-12 45.9 0.0 1.1e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 EGG06054.1 - 1.7e-12 47.9 0.3 3.4e-12 46.9 0.2 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family HAMP PF00672.20 EGG06055.1 - 7.7e-45 150.9 21.1 2e-08 34.2 0.0 7.6 6 1 1 7 7 7 7 HAMP domain Response_reg PF00072.19 EGG06055.1 - 9.3e-28 96.4 0.8 1e-25 89.8 0.3 3.2 2 1 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EGG06055.1 - 4.7e-27 93.8 0.1 3.6e-26 91.0 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGG06055.1 - 5.9e-18 64.6 3.8 9.1e-18 64.0 0.5 3.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain NAAA-beta PF15508.1 EGG06055.1 - 0.024 14.9 1.5 8.3 6.8 0.1 4.9 4 1 1 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF1149 PF06619.6 EGG06055.1 - 0.031 14.1 0.2 2.6 7.9 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1149) VBS PF08913.5 EGG06055.1 - 1.6 8.9 13.3 8.3 6.6 0.1 5.0 5 0 0 5 5 5 0 Vinculin Binding Site zf-H2C2_2 PF13465.1 EGG06058.1 - 3e-07 30.3 0.7 8.5e-07 28.9 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGG06058.1 - 0.0058 16.8 0.2 0.0058 16.8 0.1 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG06058.1 - 0.73 10.3 6.8 2.2 8.8 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DnaJ PF00226.26 EGG06059.1 - 2.7e-23 81.4 0.8 4.7e-23 80.7 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGG06059.1 - 9.3e-17 60.7 1.0 2.2e-14 53.1 0.0 3.3 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGG06059.1 - 9.3e-14 51.2 16.2 9.3e-14 51.2 11.2 1.6 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 EGG06059.1 - 0.12 12.0 10.2 0.99 9.1 1.7 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Ion_trans PF00520.26 EGG06060.1 - 5e-98 326.2 92.3 4e-35 120.8 7.0 5.9 7 0 0 7 7 7 5 Ion transport protein Holin_LLH PF09682.5 EGG06062.1 - 1.5 8.9 5.4 2.8 8.0 3.8 1.4 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) TniB PF05621.6 EGG06063.1 - 0.0067 15.2 0.2 0.018 13.8 0.1 1.7 2 0 0 2 2 2 1 Bacterial TniB protein OTU PF02338.14 EGG06064.1 - 0.002 18.6 0.0 0.0037 17.8 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease DUF2040 PF09745.4 EGG06066.1 - 1.6e-32 112.0 16.3 1.6e-32 112.0 11.3 3.6 3 2 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) UBA PF00627.26 EGG06067.1 - 0.63 9.9 1.0 1.3 8.9 0.7 1.4 1 0 0 1 1 1 0 UBA/TS-N domain GATA PF00320.22 EGG06068.1 - 2.9e-10 39.3 0.4 2.9e-10 39.3 0.3 1.6 2 0 0 2 2 2 1 GATA zinc finger Copper-fist PF00649.13 EGG06069.1 - 9e-18 63.1 2.1 9e-18 63.1 1.5 2.4 1 1 1 2 2 2 2 Copper fist DNA binding domain LTP_2 PF14368.1 EGG06069.1 - 0.46 10.6 4.2 0.56 10.3 2.9 1.2 1 0 0 1 1 1 0 Probable lipid transfer Zn-ribbon_8 PF09723.5 EGG06069.1 - 6 6.9 9.5 3.1 7.8 3.1 2.7 1 1 1 2 2 2 0 Zinc ribbon domain Med7 PF05983.6 EGG06071.1 - 1.4e-23 83.4 2.3 2.6e-23 82.5 1.6 1.3 1 0 0 1 1 1 1 MED7 protein DUF676 PF05057.9 EGG06072.1 - 4.3e-06 26.1 0.0 1.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGG06072.1 - 0.0019 17.8 0.0 0.0044 16.6 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGG06072.1 - 0.0047 16.6 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family eIF3g PF12353.3 EGG06073.1 - 2.3e-37 127.7 0.1 3.5e-37 127.1 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EGG06073.1 - 1.5e-17 62.9 0.0 2.9e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG06073.1 - 2.3e-14 53.1 0.0 4.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG06073.1 - 2.6e-09 36.7 0.0 6.6e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGG06073.1 - 0.006 16.3 0.0 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Mago-bind PF09282.5 EGG06073.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Mago binding 3-HAO PF06052.7 EGG06074.1 - 5.2e-55 184.9 0.0 6.5e-55 184.6 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EGG06074.1 - 1.3e-05 24.5 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EGG06074.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Cupin ARD PF03079.9 EGG06074.1 - 0.0087 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family LTD PF00932.14 EGG06075.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Lamin Tail Domain YqzE PF14038.1 EGG06075.1 - 0.15 11.7 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 YqzE-like protein SBP PF03110.9 EGG06076.1 - 0.059 13.6 0.3 0.17 12.1 0.2 1.8 1 0 0 1 1 1 0 SBP domain KIAA1328 PF15369.1 EGG06076.1 - 7.5 6.2 14.2 2.1 8.0 4.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 Pkinase PF00069.20 EGG06077.1 - 3.6e-66 222.9 1.2 8.8e-66 221.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG06077.1 - 3.8e-31 108.1 0.5 3.6e-30 104.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGG06077.1 - 1.2e-08 35.3 3.2 8.7e-08 32.5 2.2 2.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGG06077.1 - 2.3e-06 26.7 0.0 6.6e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 EGG06077.1 - 1.2e-05 25.0 0.0 0.032 14.0 0.0 2.7 2 0 0 2 2 2 2 C2 domain Kdo PF06293.9 EGG06077.1 - 0.043 12.8 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_4 PF14570.1 EGG06078.1 - 4.4e-21 74.1 12.4 7.3e-21 73.4 8.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EGG06078.1 - 2.2e-05 24.0 7.1 3.7e-05 23.3 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EGG06078.1 - 0.0044 16.7 3.3 0.0095 15.6 2.3 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 EGG06078.1 - 0.0069 16.3 12.0 0.012 15.5 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-TFIIIC PF12660.2 EGG06078.1 - 0.15 11.9 1.4 0.3 11.0 1.0 1.4 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex Baculo_IE-1 PF05290.6 EGG06078.1 - 0.44 10.2 2.7 0.88 9.3 1.9 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DNA_pol_phi PF04931.8 EGG06080.1 - 6.5e-26 90.3 25.0 3.5e-19 68.1 15.0 3.1 3 0 0 3 3 3 2 DNA polymerase phi DUF605 PF04652.11 EGG06084.1 - 9.5 5.4 10.5 12 5.2 7.3 1.0 1 0 0 1 1 1 0 Vta1 like GET2 PF08690.5 EGG06086.1 - 0.01 15.1 1.3 0.01 15.1 0.9 1.7 2 0 0 2 2 2 0 GET complex subunit GET2 S1 PF00575.18 EGG06086.1 - 0.079 13.0 0.1 0.27 11.3 0.1 1.9 1 0 0 1 1 1 0 S1 RNA binding domain DUF3591 PF12157.3 EGG06086.1 - 1.5 7.1 5.7 0.17 10.2 0.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3591) Alpha_kinase PF02816.13 EGG06088.1 - 2.4e-15 56.6 0.1 3.7e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family Sugarporin_N PF11471.3 EGG06091.1 - 0.018 14.6 0.6 0.041 13.5 0.4 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension End3 PF12761.2 EGG06091.1 - 0.024 14.2 0.7 0.041 13.5 0.5 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 COG5 PF10392.4 EGG06091.1 - 0.082 12.8 2.9 0.22 11.5 0.6 2.3 1 1 0 2 2 2 0 Golgi transport complex subunit 5 Uds1 PF15456.1 EGG06091.1 - 0.9 9.5 5.6 13 5.7 0.0 2.7 2 1 0 2 2 2 0 Up-regulated During Septation FliD_N PF02465.13 EGG06091.1 - 1.3 9.3 5.5 0.27 11.6 0.8 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Fmp27_WPPW PF10359.4 EGG06092.1 - 0.013 13.9 2.0 0.015 13.7 1.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain USP8_interact PF08941.5 EGG06092.1 - 0.031 13.6 0.2 0.045 13.0 0.1 1.2 1 0 0 1 1 1 0 USP8 interacting Fib_alpha PF08702.5 EGG06092.1 - 0.044 13.9 0.5 0.056 13.5 0.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Streptin-Immun PF11083.3 EGG06092.1 - 0.047 13.6 1.5 1.7 8.6 0.2 2.1 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein MannoseP_isomer PF01050.13 EGG06092.1 - 0.061 12.9 0.2 0.069 12.7 0.1 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Rogdi_lz PF10259.4 EGG06092.1 - 0.069 12.2 2.3 0.088 11.8 1.6 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Sec5 PF15469.1 EGG06092.1 - 0.11 12.2 1.7 0.15 11.8 1.2 1.3 1 1 0 1 1 1 0 Exocyst complex component Sec5 Vir_act_alpha_C PF10400.4 EGG06092.1 - 1.2 9.5 4.4 1.1 9.6 0.7 2.1 1 1 1 2 2 2 0 Virulence activator alpha C-term zf-CCHC PF00098.18 EGG06093.1 - 0.01 15.7 1.2 0.022 14.6 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle RHH_1 PF01402.16 EGG06094.1 - 0.026 14.4 2.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Rabaptin PF03528.10 EGG06096.1 - 0.0021 17.9 0.2 0.0039 17.0 0.1 1.3 1 0 0 1 1 1 1 Rabaptin LOH1CR12 PF10158.4 EGG06096.1 - 0.0099 15.6 0.2 0.021 14.6 0.1 1.5 1 0 0 1 1 1 1 Tumour suppressor protein DUF482 PF04339.7 EGG06097.1 - 0.069 12.0 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF482 Phage_antitermQ PF06530.7 EGG06098.1 - 0.059 12.9 0.2 0.72 9.4 0.0 2.1 2 0 0 2 2 2 0 Phage antitermination protein Q SUV3_C PF12513.3 EGG06098.1 - 0.11 12.0 0.5 0.29 10.6 0.4 1.8 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal BCNT PF07572.7 EGG06098.1 - 0.47 10.4 7.2 0.69 9.8 5.0 1.4 1 0 0 1 1 1 0 Bucentaur or craniofacial development PQ-loop PF04193.9 EGG06099.1 - 8.3e-33 111.7 17.3 2.2e-17 62.3 1.6 3.4 3 0 0 3 3 3 2 PQ loop repeat Kinesin PF00225.18 EGG06104.1 - 1.2e-110 369.4 0.0 3.2e-110 367.9 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain HOOK PF05622.7 EGG06104.1 - 1.3 6.7 74.2 0.0029 15.4 21.3 2.9 1 1 2 3 3 3 0 HOOK protein WD40 PF00400.27 EGG06105.1 - 3.9e-26 89.9 5.5 3.2e-06 26.8 0.1 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGG06105.1 - 1.5e-06 28.0 0.1 0.0022 17.7 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGG06105.1 - 0.025 12.8 0.3 0.052 11.8 0.1 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain TFIIIC_delta PF12657.2 EGG06105.1 - 0.13 11.9 4.8 0.43 10.2 0.2 3.9 4 1 0 4 4 4 0 Transcription factor IIIC subunit delta N-term SURF6 PF04935.7 EGG06108.1 - 7.2e-24 84.2 62.2 1.4e-23 83.3 36.7 3.1 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 EGG06108.1 - 3.5e-09 36.5 0.8 3.5e-09 36.5 0.5 5.4 4 1 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 Zn_clus PF00172.13 EGG06109.1 - 5.6e-08 32.5 7.9 9.9e-08 31.7 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EGG06111.1 - 5.8e-58 196.0 0.0 7.2e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG06111.1 - 3.5e-23 82.0 0.0 5.1e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG06111.1 - 2.2e-05 23.5 0.0 4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGG06111.1 - 0.00013 21.8 0.4 0.22 11.2 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGG06111.1 - 0.027 14.0 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_S8e PF01201.17 EGG06112.1 - 4.2e-36 123.9 2.5 4.9e-36 123.7 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EGG06112.1 - 2.3 8.5 6.8 0.26 11.5 1.3 2.1 2 1 0 2 2 2 0 Small acidic protein family Alpha_kinase PF02816.13 EGG06113.1 - 2.4e-17 63.2 0.0 8.4e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 Alpha-kinase family Nitrate_red_gam PF02665.9 EGG06115.1 - 0.038 13.3 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Peptidase_M7 PF02031.11 EGG06115.1 - 0.042 13.5 0.1 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family GSG-1 PF07803.6 EGG06115.1 - 2.5 7.6 6.2 23 4.6 4.3 2.1 1 1 0 1 1 1 0 GSG1-like protein OTU PF02338.14 EGG06117.1 - 1.9e-20 73.6 0.1 4.2e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGG06117.1 - 0.00024 20.5 0.0 0.024 13.9 0.0 2.7 3 1 0 3 3 3 1 Peptidase C65 Otubain YihI PF04220.7 EGG06117.1 - 0.047 13.0 3.2 0.056 12.7 1.3 1.8 2 0 0 2 2 2 0 Der GTPase activator (YihI) 23S_rRNA_IVP PF05635.6 EGG06117.1 - 0.05 13.5 0.0 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein DUF1664 PF07889.7 EGG06117.1 - 0.12 12.1 0.2 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1878 PF08963.5 EGG06117.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) RasGAP_C PF03836.10 EGG06117.1 - 4.5 6.9 7.7 8.9 5.9 0.6 3.6 3 1 1 4 4 4 0 RasGAP C-terminus DUF35_N PF12172.3 EGG06119.1 - 0.24 11.3 3.8 2.4 8.1 0.4 2.7 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FKS1_dom1 PF14288.1 EGG06121.1 - 0.0027 17.6 0.3 0.024 14.5 0.1 2.4 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Myb_DNA-bind_3 PF12776.2 EGG06121.1 - 0.13 12.9 3.3 3.7 8.2 0.3 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain GCFC PF07842.7 EGG06122.1 - 1.6e-57 194.9 13.6 2.7e-57 194.2 9.5 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EGG06122.1 - 7.8e-15 54.3 3.2 2.3e-14 52.8 2.2 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGG06122.1 - 1.3e-05 24.9 0.3 1.3e-05 24.9 0.2 3.1 2 1 0 2 2 2 1 DExH-box splicing factor binding site TIP_N PF12457.3 EGG06122.1 - 2.5e-05 24.3 15.7 2.5e-05 24.3 10.9 3.7 3 1 0 3 3 3 1 Tuftelin interacting protein N terminal Col_cuticle_N PF01484.12 EGG06124.1 - 0.016 14.8 0.1 0.026 14.2 0.1 1.2 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain DUF1049 PF06305.6 EGG06124.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Herpes_gE PF02480.11 EGG06124.1 - 0.091 11.0 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TSGA13 PF14994.1 EGG06124.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Testis-specific gene 13 protein SRF-TF PF00319.13 EGG06126.1 - 1.1e-17 62.9 0.1 2.1e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF2435 PF10363.4 EGG06127.1 - 2.5e-17 62.5 0.2 9.6e-17 60.6 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EGG06127.1 - 0.001 18.5 0.3 0.003 17.0 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) RRM_1 PF00076.17 EGG06128.1 - 1.7e-18 66.0 0.0 2.3e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG06128.1 - 1.3e-15 57.0 0.0 1.9e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG06128.1 - 1.2e-07 31.4 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3810 PF12725.2 EGG06131.1 - 0.065 12.1 0.3 0.091 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Abhydrolase_2 PF02230.11 EGG06133.1 - 6.9e-29 100.8 0.1 6e-28 97.7 0.1 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 EGG06133.1 - 0.00015 21.2 0.0 0.00025 20.5 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EGG06133.1 - 0.0055 16.4 0.0 0.007 16.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Patatin PF01734.17 EGG06133.1 - 0.064 13.1 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase HgmA PF04209.8 EGG06134.1 - 1.3e-123 412.5 0.0 1.5e-123 412.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Pkinase PF00069.20 EGG06135.1 - 1.9e-24 86.2 0.0 2.2e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG06135.1 - 1.6e-15 56.9 0.0 2.1e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG06135.1 - 0.0052 16.5 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGG06135.1 - 0.007 15.3 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGG06135.1 - 0.017 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-U1 PF06220.7 EGG06136.1 - 4.5e-19 67.7 1.9 6.6e-19 67.1 1.3 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EGG06136.1 - 0.6 10.3 5.2 2.3 8.4 3.6 1.9 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Hus1 PF04005.7 EGG06137.1 - 1.4e-44 152.2 0.0 1.7e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein BRCT PF00533.21 EGG06138.1 - 1.5e-09 37.8 0.0 5e-09 36.1 0.0 1.9 1 1 1 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGG06138.1 - 8.8e-06 25.4 0.0 6.4e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 twin BRCT domain fn3 PF00041.16 EGG06138.1 - 0.028 14.5 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain P21-Arc PF04062.9 EGG06139.1 - 2.8e-68 229.1 0.0 3.1e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 EGG06139.1 - 1.1 9.3 3.3 3.1 7.8 0.0 2.7 3 0 0 3 3 3 0 Pancreatic hormone peptide TPR_11 PF13414.1 EGG06142.1 - 1.6e-11 43.6 0.2 9.9e-11 41.1 0.1 2.2 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EGG06142.1 - 6.3e-08 31.9 0.0 0.00012 21.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGG06142.1 - 1.5e-05 24.5 0.0 0.015 15.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.26 EGG06142.1 - 0.00043 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_8 PF13181.1 EGG06142.1 - 0.01 15.5 0.0 0.042 13.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGG06142.1 - 0.014 15.3 0.1 0.064 13.2 0.1 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGG06142.1 - 0.1 12.4 0.0 0.48 10.3 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Methyltransf_16 PF10294.4 EGG06143.1 - 6.5e-15 55.0 0.2 1.4e-14 53.9 0.2 1.5 1 1 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 EGG06143.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_23 PF13489.1 EGG06143.1 - 0.0052 16.5 0.0 0.0083 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG06143.1 - 0.013 15.9 0.0 0.08 13.4 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EGG06143.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 EGG06143.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Dynamitin PF04912.9 EGG06145.1 - 1.5e-27 96.4 23.7 6.8e-15 54.7 0.4 3.5 2 1 0 2 2 2 2 Dynamitin GIDA_assoc_3 PF13932.1 EGG06145.1 - 0.068 13.2 3.5 0.13 12.3 0.0 2.7 2 0 0 2 2 2 0 GidA associated domain 3 Baculo_PEP_C PF04513.7 EGG06145.1 - 1.3 8.8 17.7 0.26 11.1 0.2 3.9 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus PMC2NT PF08066.7 EGG06145.1 - 1.8 8.9 6.5 0.79 10.0 1.0 2.9 3 0 0 3 3 3 0 PMC2NT (NUC016) domain PspB PF06667.7 EGG06145.1 - 1.9 8.4 9.6 5.7 6.9 0.3 3.9 4 1 0 4 4 4 0 Phage shock protein B RTX_C PF08339.5 EGG06145.1 - 8.4 6.0 9.7 0.22 11.2 0.6 2.7 2 1 1 3 3 3 0 RTX C-terminal domain Steroid_dh PF02544.11 EGG06148.1 - 8.3e-30 103.5 2.0 8.3e-30 103.5 1.4 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 EGG06148.1 - 0.00062 19.1 0.6 0.00062 19.1 0.4 2.0 2 0 0 2 2 2 1 Ubiquitin family DUF1295 PF06966.7 EGG06148.1 - 0.0015 17.9 1.7 0.0021 17.4 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Ubiquitin_2 PF14560.1 EGG06148.1 - 0.018 15.2 0.5 0.05 13.8 0.4 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain PDR_assoc PF08370.6 EGG06148.1 - 0.043 13.3 1.1 6 6.4 0.0 2.8 3 0 0 3 3 3 0 Plant PDR ABC transporter associated TPR_11 PF13414.1 EGG06150.1 - 7.1e-15 54.4 2.3 1.1e-10 41.0 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGG06150.1 - 3.2e-09 36.0 2.2 0.02 14.4 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGG06150.1 - 2.3e-07 30.2 2.9 0.062 13.2 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGG06150.1 - 0.00061 19.6 0.9 0.0059 16.5 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGG06150.1 - 0.0015 18.5 0.3 4.2 7.8 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG06150.1 - 0.011 15.5 0.2 0.66 9.9 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGG06150.1 - 0.036 13.9 0.3 0.28 11.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGG06150.1 - 0.042 14.4 1.1 2.1 9.2 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGG06150.1 - 0.057 14.1 2.8 10 6.9 0.3 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 EGG06150.1 - 0.12 12.1 3.0 6 6.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Cadherin-like PF12733.2 EGG06150.1 - 0.13 12.5 0.3 0.28 11.4 0.1 1.6 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain TPR_8 PF13181.1 EGG06150.1 - 0.15 11.9 0.2 40 4.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RWD PF05773.17 EGG06152.1 - 0.03 14.2 0.1 0.087 12.7 0.1 1.8 1 0 0 1 1 1 0 RWD domain DUF739 PF05339.6 EGG06152.1 - 0.071 12.9 0.5 0.15 11.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF739) UvrD_C PF13361.1 EGG06154.1 - 1.5e-63 215.4 0.0 8.2e-63 212.9 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EGG06154.1 - 3.1e-48 164.7 0.0 1.3e-47 162.6 0.0 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EGG06154.1 - 1.8e-12 47.2 0.0 5.5e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EGG06154.1 - 3.9e-07 29.7 0.0 1.6e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_12 PF13087.1 EGG06154.1 - 0.029 13.7 0.0 0.11 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain NDK PF00334.14 EGG06157.1 - 4.4e-49 165.7 0.0 5.7e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Cation_efflux PF01545.16 EGG06158.1 - 3.5e-51 173.9 1.2 4.7e-51 173.5 0.8 1.2 1 0 0 1 1 1 1 Cation efflux family SET PF00856.23 EGG06161.1 - 1.5e-07 31.8 0.0 3.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 SET domain Peroxidase_2 PF01328.12 EGG06162.1 - 3.1e-09 35.9 0.1 4.8e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 TMCO5 PF14992.1 EGG06163.1 - 0.0036 16.4 0.2 0.0043 16.2 0.2 1.1 1 0 0 1 1 1 1 TMCO5 family HDV_ag PF01517.13 EGG06165.1 - 0.098 12.3 3.0 0.11 12.1 2.1 1.1 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Peptidase_C97 PF05903.9 EGG06166.1 - 0.086 12.6 0.7 0.18 11.5 0.5 1.6 1 1 0 1 1 1 0 PPPDE putative peptidase domain Nop14 PF04147.7 EGG06167.1 - 0.042 11.7 11.4 0.066 11.1 7.9 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EGG06167.1 - 0.056 11.9 10.9 0.088 11.2 7.6 1.3 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EGG06167.1 - 0.062 12.5 6.6 0.094 11.9 4.6 1.3 1 0 0 1 1 1 0 SDA1 DUF2404 PF10296.4 EGG06167.1 - 0.063 13.4 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) CDC45 PF02724.9 EGG06167.1 - 0.066 11.2 3.2 0.085 10.8 2.2 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 EGG06167.1 - 0.64 9.0 10.2 1.1 8.3 7.1 1.3 1 0 0 1 1 1 0 BUD22 MoCF_biosynth PF00994.19 EGG06168.1 - 1.2e-39 134.9 0.0 1.2e-19 70.1 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EGG06168.1 - 9.2e-26 90.1 0.0 1.5e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EGG06168.1 - 1.7e-07 31.0 0.0 3.5e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Ndc1_Nup PF09531.5 EGG06168.1 - 0.043 12.2 1.5 0.066 11.6 1.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cep57_MT_bd PF06657.8 EGG06170.1 - 0.026 14.4 8.2 0.35 10.8 4.5 3.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TBPIP PF07106.8 EGG06170.1 - 0.13 11.8 14.5 0.067 12.7 4.2 3.1 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Vac_Fusion PF02346.11 EGG06170.1 - 0.13 11.6 1.2 1.7 8.1 0.0 3.2 3 0 0 3 3 3 0 Chordopoxvirus fusion protein MAD PF05557.8 EGG06170.1 - 0.13 10.3 13.8 0.13 10.2 8.7 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein FlaC_arch PF05377.6 EGG06170.1 - 0.21 11.4 7.0 1.4 8.8 0.7 3.0 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) LPP PF04728.8 EGG06170.1 - 0.24 11.2 5.4 4.3 7.2 0.4 3.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF948 PF06103.6 EGG06170.1 - 0.31 10.9 3.7 1.4 8.8 0.4 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.2 EGG06170.1 - 0.53 10.1 15.9 2 8.2 3.8 3.5 2 1 1 3 3 3 0 Tropomyosin like NTR2 PF15458.1 EGG06170.1 - 0.78 8.9 10.2 1.8 7.7 1.8 2.7 3 0 0 3 3 3 0 Nineteen complex-related protein 2 IncA PF04156.9 EGG06170.1 - 0.83 9.2 23.6 5.3 6.5 6.0 3.8 2 1 1 3 3 3 0 IncA protein CENP-F_leu_zip PF10473.4 EGG06170.1 - 2 8.2 16.5 2 8.2 8.8 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 EGG06170.1 - 2 8.4 7.2 3.6 7.6 2.3 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CASP_C PF08172.7 EGG06170.1 - 2.6 7.0 13.1 0.38 9.7 3.9 3.0 2 1 1 3 3 3 0 CASP C terminal ATG16 PF08614.6 EGG06170.1 - 2.9 7.6 19.3 0.3 10.8 7.3 2.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 EGG06170.1 - 3.2 7.7 9.1 1.1 9.2 0.5 3.5 3 1 0 3 3 3 0 bZIP transcription factor NPV_P10 PF05531.7 EGG06170.1 - 3.2 8.0 5.5 34 4.7 0.1 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YlqD PF11068.3 EGG06170.1 - 3.2 7.7 13.8 1.9 8.5 6.9 2.4 2 0 0 2 2 2 0 YlqD protein DUF3573 PF12097.3 EGG06170.1 - 3.5 6.1 4.9 6 5.3 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) DUF1664 PF07889.7 EGG06170.1 - 3.5 7.4 7.5 1.6 8.5 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 EGG06170.1 - 4.6 7.6 12.2 4.7 7.6 4.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EGG06170.1 - 5.3 6.9 7.9 0.35 10.7 0.8 2.5 3 0 0 3 3 3 0 Basic region leucine zipper DUF4200 PF13863.1 EGG06170.1 - 9.6 6.1 14.0 4 7.4 1.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) MIF4G PF02854.14 EGG06171.1 - 0.017 14.5 0.4 0.023 14.1 0.2 1.1 1 0 0 1 1 1 0 MIF4G domain DUF4197 PF13852.1 EGG06173.1 - 0.033 13.7 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) Glyco_hydro_26 PF02156.10 EGG06174.1 - 0.0016 17.9 5.3 0.0091 15.5 0.6 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 26 ADH_zinc_N_2 PF13602.1 EGG06177.1 - 0.0019 19.0 0.0 0.0037 18.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EGG06177.1 - 0.0076 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.20 EGG06178.1 - 1.4e-47 162.0 0.0 1.6e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG06178.1 - 1.3e-29 103.0 0.0 1.6e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGG06178.1 - 1.2e-06 27.7 0.1 1.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGG06178.1 - 0.00028 19.9 0.2 0.0012 17.9 0.1 1.9 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGG06178.1 - 0.0094 14.8 0.3 0.015 14.1 0.2 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EGG06178.1 - 0.024 14.3 0.1 0.039 13.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DDHD PF02862.12 EGG06181.1 - 0.81 9.4 6.7 1.4 8.6 4.7 1.4 1 0 0 1 1 1 0 DDHD domain DUF2215 PF10225.4 EGG06181.1 - 10 5.5 7.7 0.38 10.1 1.4 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Peroxidase_2 PF01328.12 EGG06182.1 - 1e-14 53.9 0.2 1.6e-14 53.3 0.2 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Sec3_C PF09763.4 EGG06183.1 - 0.096 10.8 6.4 0.11 10.6 4.5 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 RAP1 PF07218.6 EGG06183.1 - 0.41 8.6 3.9 0.47 8.4 2.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ubiquitin PF00240.18 EGG06184.1 - 2.8e-33 113.1 0.4 6e-33 112.0 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EGG06184.1 - 9e-28 95.8 1.4 1.8e-27 94.8 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EGG06184.1 - 5.5e-20 70.8 0.7 1.1e-19 69.9 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGG06184.1 - 2.5e-05 24.4 0.2 0.00013 22.1 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGG06184.1 - 0.00063 19.6 0.6 0.0014 18.5 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 EGG06184.1 - 0.0016 18.1 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 EGG06184.1 - 0.019 15.1 0.5 0.026 14.7 0.4 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Plexin_cytopl PF08337.7 EGG06184.1 - 0.042 12.1 2.6 0.46 8.7 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Stig1 PF04885.8 EGG06184.1 - 0.13 12.4 0.8 0.17 12.1 0.6 1.5 1 1 0 1 1 1 0 Stigma-specific protein, Stig1 DCX PF03607.12 EGG06185.1 - 0.12 11.9 0.0 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 Doublecortin Arc_PepC PF06819.6 EGG06187.1 - 0.11 12.3 0.1 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain MaoC_dehydratas PF01575.14 EGG06188.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain DUF1365 PF07103.6 EGG06189.1 - 2.3e-19 69.4 0.1 3.2e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) FAD_binding_3 PF01494.14 EGG06190.1 - 5.8e-78 262.4 0.0 1.7e-57 195.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.7 EGG06190.1 - 5.4e-45 153.0 0.0 8.6e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain ThiF PF00899.16 EGG06190.1 - 7e-05 22.6 0.3 0.00015 21.6 0.1 1.6 2 0 0 2 2 1 1 ThiF family FAD_binding_2 PF00890.19 EGG06190.1 - 9.6e-05 21.4 0.1 0.00014 20.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGG06190.1 - 0.00011 22.1 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGG06190.1 - 0.00028 19.5 0.2 0.00041 18.9 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 EGG06190.1 - 0.00081 18.3 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGG06190.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EGG06190.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGG06190.1 - 0.0034 16.0 0.1 0.0047 15.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EGG06190.1 - 0.011 14.6 0.2 0.018 13.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EGG06190.1 - 0.012 15.7 0.1 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGG06190.1 - 0.015 15.0 0.1 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EGG06190.1 - 0.016 14.0 1.6 0.037 12.8 0.9 1.6 1 1 1 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EGG06190.1 - 0.032 14.3 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EGG06190.1 - 0.055 12.5 0.3 0.083 11.9 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGG06190.1 - 0.16 12.4 0.1 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EGG06190.1 - 0.19 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SOCS_box PF07525.11 EGG06191.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 SOCS box PHD PF00628.24 EGG06194.1 - 6.5e-07 28.9 10.1 1.2e-06 28.0 7.0 1.5 1 0 0 1 1 1 1 PHD-finger TGS PF02824.16 EGG06195.1 - 3.8e-17 61.8 0.1 7.2e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EGG06195.1 - 6.9e-17 61.4 0.0 1.7e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGG06195.1 - 1.1e-08 34.5 0.2 2.2e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B zf-C2H2 PF00096.21 EGG06198.1 - 1.6e-11 43.8 29.5 3.5e-05 23.8 1.0 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG06198.1 - 8.9e-11 41.3 34.4 0.00025 21.1 1.7 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger SprT-like PF10263.4 EGG06198.1 - 0.00034 20.2 2.3 0.48 10.0 0.0 2.5 2 0 0 2 2 2 2 SprT-like family zf-H2C2_5 PF13909.1 EGG06198.1 - 0.0012 18.9 6.2 0.061 13.5 0.6 3.3 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EGG06198.1 - 0.0021 18.1 16.9 0.027 14.6 0.1 4.0 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding Rpr2 PF04032.11 EGG06198.1 - 0.14 12.0 9.0 1.3 8.9 1.2 2.7 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-met PF12874.2 EGG06198.1 - 0.15 12.3 15.6 2.4 8.4 0.3 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 EGG06198.1 - 0.28 11.4 13.3 0.052 13.8 1.7 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF629 PF04780.7 EGG06198.1 - 0.79 8.1 18.0 0.29 9.6 0.2 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 EGG06198.1 - 2.1 8.5 16.4 1.6 8.8 0.7 4.5 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EGG06198.1 - 3.2 8.2 25.1 0.22 11.9 0.5 5.3 6 0 0 6 6 6 0 Zinc-finger double domain GEMIN8 PF15348.1 EGG06201.1 - 0.26 11.2 3.6 0.27 11.2 2.5 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DNA_pol_phi PF04931.8 EGG06201.1 - 1.5 6.4 11.4 1.8 6.2 7.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi PQQ PF01011.16 EGG06202.1 - 0.019 14.4 0.1 0.041 13.4 0.1 1.5 1 0 0 1 1 1 0 PQQ enzyme repeat Pro_isomerase PF00160.16 EGG06204.1 - 2.6e-44 151.1 0.2 3.2e-44 150.8 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NPV_P10 PF05531.7 EGG06208.1 - 0.0075 16.4 1.0 0.044 14.0 0.7 2.1 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EGG06208.1 - 0.0085 15.9 2.9 0.014 15.2 2.0 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus LIF_OSM PF01291.12 EGG06208.1 - 0.049 13.5 0.2 0.095 12.6 0.1 1.4 1 0 0 1 1 1 0 LIF / OSM family Spc7 PF08317.6 EGG06208.1 - 0.067 11.8 2.4 0.048 12.3 0.4 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Lactonase PF10282.4 EGG06211.1 - 4.1e-61 206.9 0.6 4.9e-61 206.7 0.4 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Abhydrolase_1 PF00561.15 EGG06211.1 - 0.027 14.0 0.1 0.065 12.7 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF717 PF05338.7 EGG06211.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF717) Lactonase PF10282.4 EGG06212.1 - 8e-58 196.1 0.6 2.3e-53 181.4 0.3 2.0 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller VPS9 PF02204.13 EGG06214.1 - 2.4e-14 53.2 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MFS_1 PF07690.11 EGG06217.1 - 1e-19 70.5 33.8 1.2e-17 63.6 11.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily PepSY_TM_2 PF13703.1 EGG06217.1 - 1.1 9.4 5.9 1.2 9.3 0.0 3.8 4 0 0 4 4 4 0 PepSY-associated TM helix MFS_1 PF07690.11 EGG06218.1 - 6.2e-36 123.8 29.5 1.5e-35 122.6 20.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EGG06218.1 - 0.029 14.1 0.9 0.029 14.1 0.6 3.3 4 0 0 4 4 4 0 MFS_1 like family RseC_MucC PF04246.7 EGG06218.1 - 8.2 6.0 7.1 9.7 5.7 0.3 3.0 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ECR1_N PF14382.1 EGG06219.1 - 5.3e-11 41.6 0.0 9e-11 40.8 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EGG06219.1 - 0.0095 15.8 0.0 4.1 7.4 0.0 2.3 2 0 0 2 2 2 2 Exosome component EXOSC1/CSL4 Cellulase-like PF12876.2 EGG06221.1 - 0.012 15.9 0.0 0.098 13.1 0.0 2.3 2 1 0 2 2 2 0 Sugar-binding cellulase-like RNase_H PF00075.19 EGG06224.1 - 2.6e-06 27.8 0.0 2.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 RNase H IF4E PF01652.13 EGG06225.1 - 5.1e-39 133.4 0.1 5.6e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Rep-A_N PF04057.7 EGG06226.1 - 1.7e-25 88.7 0.0 2.2e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain Myb_DNA-bind_3 PF12776.2 EGG06228.1 - 6.5e-11 42.7 5.3 2.1e-10 41.0 3.6 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Daxx PF03344.10 EGG06228.1 - 0.012 14.1 33.0 0.014 13.9 13.7 2.1 2 0 0 2 2 2 0 Daxx Family ALF PF03752.8 EGG06228.1 - 0.28 11.0 2.0 2.8 7.8 0.4 2.5 2 0 0 2 2 2 0 Short repeats of unknown function MIP-T3 PF10243.4 EGG06228.1 - 2.9 6.2 46.2 1.5 7.1 9.4 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Rep_fac-A_C PF08646.5 EGG06229.1 - 7.4e-47 158.7 0.1 1e-44 151.7 0.1 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EGG06229.1 - 3.6e-12 45.9 0.5 3.3e-10 39.6 0.1 2.5 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 EGG06229.1 - 1.2e-10 41.0 0.9 4.9e-10 39.0 0.6 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain DUF223 PF02721.9 EGG06229.1 - 0.00036 20.5 0.0 0.0008 19.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF223 SNARE_assoc PF09335.6 EGG06231.1 - 2.6e-16 59.9 5.6 2.6e-16 59.9 3.9 2.3 3 0 0 3 3 3 1 SNARE associated Golgi protein HAMP PF00672.20 EGG06231.1 - 0.11 12.7 4.6 2.7 8.2 0.0 3.2 3 0 0 3 3 3 0 HAMP domain COX2_TM PF02790.10 EGG06231.1 - 0.18 11.8 9.6 0.27 11.2 3.8 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF4293 PF14126.1 EGG06231.1 - 0.26 11.1 6.1 4 7.3 2.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) DUF4328 PF14219.1 EGG06231.1 - 0.86 8.8 6.7 2.7 7.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) AflR PF08493.5 EGG06233.1 - 0.081 11.9 1.3 0.4 9.6 0.1 1.9 1 1 1 2 2 2 0 Aflatoxin regulatory protein AvrL567-A PF11529.3 EGG06233.1 - 0.12 12.3 0.4 13 5.7 0.0 2.7 1 1 2 3 3 3 0 Melampsora lini avirulence protein AvrL567-A zf-LITAF-like PF10601.4 EGG06233.1 - 1.2 9.0 8.2 6.1 6.7 0.3 3.2 1 1 2 3 3 3 0 LITAF-like zinc ribbon domain Oleosin PF01277.12 EGG06233.1 - 2.5 7.6 5.5 4.4 6.8 0.2 2.7 1 1 2 3 3 3 0 Oleosin DUF2789 PF10982.3 EGG06234.1 - 0.042 13.8 0.4 0.086 12.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) Baculo_44 PF04631.7 EGG06235.1 - 0.14 10.7 1.4 1.7 7.2 0.2 2.0 2 0 0 2 2 2 0 Baculovirus hypothetical protein UbiA PF01040.13 EGG06236.1 - 2.7e-07 30.0 0.4 3e-07 29.9 0.3 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family WD40 PF00400.27 EGG06238.1 - 1.8e-05 24.4 5.4 0.068 13.0 0.4 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ATP-synt_D PF01813.12 EGG06238.1 - 0.36 10.3 0.0 0.65 9.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase subunit D DUF4243 PF14027.1 EGG06241.1 - 1.8e-86 290.5 1.5 2.3e-86 290.2 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF1910 PF08928.5 EGG06241.1 - 0.081 12.9 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) DNA_pol_B PF00136.16 EGG06244.1 - 5.7e-114 381.4 0.1 7.9e-114 380.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EGG06244.1 - 1e-58 197.7 1.4 1.6e-58 197.1 1.0 1.3 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EGG06244.1 - 2.2e-25 89.1 0.0 4.1e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Pkinase PF00069.20 EGG06245.1 - 1.7e-27 96.1 0.0 4.4e-22 78.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGG06245.1 - 1.9e-10 40.2 0.0 3.3e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG06245.1 - 0.029 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGG06245.1 - 0.053 12.5 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Inhibitor_I71 PF12628.2 EGG06246.1 - 0.048 13.3 0.9 0.083 12.5 0.6 1.3 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor DUF2638 PF10937.3 EGG06246.1 - 3.4 8.7 13.0 14 6.7 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) Tmemb_cc2 PF10267.4 EGG06247.1 - 6 5.3 8.5 9.5 4.6 5.9 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.4 EGG06247.1 - 9.5 4.3 12.9 12 3.9 9.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Utp12 PF04003.7 EGG06248.1 - 8.8e-14 51.3 2.6 1.9e-13 50.2 1.8 1.6 1 1 0 1 1 1 1 Dip2/Utp12 Family UTP15_C PF09384.5 EGG06248.1 - 0.0026 17.4 0.1 0.0047 16.6 0.1 1.4 1 0 0 1 1 1 1 UTP15 C terminal DUF2563 PF10817.3 EGG06249.1 - 0.033 14.6 0.0 0.051 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2563) DUF4316 PF14195.1 EGG06249.1 - 0.042 13.9 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) FlxA PF14282.1 EGG06251.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.3 4 0 0 4 4 4 0 FlxA-like protein Period_C PF12114.3 EGG06251.1 - 0.18 11.3 3.5 0.33 10.5 2.4 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF3896 PF13035.1 EGG06251.1 - 0.26 11.3 1.8 5.5 7.1 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3896) Peptidase_C54 PF03416.14 EGG06252.1 - 0.0008 18.6 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 FAR1 PF03101.10 EGG06253.1 - 0.037 14.5 0.1 0.037 14.5 0.1 3.2 3 1 0 3 3 3 0 FAR1 DNA-binding domain D123 PF07065.9 EGG06254.1 - 4e-20 72.1 0.1 2.2e-19 69.6 0.0 1.9 1 1 0 1 1 1 1 D123 DUF3469 PF11952.3 EGG06254.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) CAP_C PF08603.6 EGG06259.1 - 0.014 14.7 0.6 0.017 14.4 0.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Kinocilin PF15033.1 EGG06259.1 - 0.086 12.3 0.0 0.12 11.9 0.0 1.2 1 1 0 1 1 1 0 Kinocilin protein FYVE_2 PF02318.11 EGG06261.1 - 0.35 10.7 2.8 0.46 10.4 1.9 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger ABC2_membrane PF01061.19 EGG06263.1 - 4.4e-22 78.2 18.4 4.4e-22 78.2 12.8 2.7 2 1 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 EGG06263.1 - 1.7e-14 53.3 0.0 3.4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 CDR ABC transporter F-box PF00646.28 EGG06265.1 - 0.0088 15.6 0.2 0.026 14.2 0.2 1.8 1 0 0 1 1 1 1 F-box domain FCH PF00611.18 EGG06272.1 - 1.4e-17 63.5 0.1 3.7e-17 62.2 0.1 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EGG06272.1 - 1.8e-10 40.0 0.1 3.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGG06272.1 - 1.1e-07 31.1 0.0 2.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EGG06272.1 - 4.6e-07 29.3 0.0 8.7e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SCF PF02404.10 EGG06275.1 - 0.0025 17.0 0.2 0.0025 17.0 0.1 2.0 2 0 0 2 2 2 1 Stem cell factor Amnionless PF14828.1 EGG06275.1 - 0.028 12.9 0.0 0.049 12.1 0.0 1.3 1 0 0 1 1 1 0 Amnionless DUF2207 PF09972.4 EGG06275.1 - 0.041 12.4 0.0 0.065 11.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FixQ PF05545.6 EGG06275.1 - 0.16 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Rifin_STEVOR PF02009.11 EGG06275.1 - 0.3 10.6 0.0 0.3 10.6 0.0 2.0 3 0 0 3 3 3 0 Rifin/stevor family Peptidase_M28 PF04389.12 EGG06276.1 - 1.5e-24 86.7 0.0 2.8e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGG06276.1 - 0.00068 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cwf_Cwc_15 PF04889.7 EGG06283.1 - 3.4 7.2 17.6 4.4 6.9 12.2 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1764 PF08576.5 EGG06283.1 - 4 8.2 10.4 2.3 9.0 5.6 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) HTH_29 PF13551.1 EGG06284.1 - 2.4e-05 24.4 0.0 4.4e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EGG06284.1 - 9.1e-05 23.1 0.0 0.00019 22.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Arg_repressor PF01316.16 EGG06284.1 - 0.0002 20.8 0.0 0.00057 19.3 0.0 1.7 2 0 0 2 2 2 1 Arginine repressor, DNA binding domain HTH_28 PF13518.1 EGG06284.1 - 0.0073 16.2 0.1 0.016 15.1 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.13 EGG06284.1 - 0.047 13.4 0.0 0.078 12.6 0.0 1.3 1 1 0 1 1 1 0 'Paired box' domain Zn_Tnp_IS1595 PF12760.2 EGG06286.1 - 0.094 12.5 4.2 0.35 10.6 2.9 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain SNARE_assoc PF09335.6 EGG06287.1 - 2.2e-16 60.1 6.8 1.3e-15 57.6 3.4 2.6 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF2370 PF10176.4 EGG06287.1 - 0.1 11.9 0.2 0.72 9.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) EMP24_GP25L PF01105.19 EGG06287.1 - 2.6 7.7 4.6 4.6 6.9 0.2 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4149 PF13664.1 EGG06287.1 - 8.4 6.5 10.4 6.6 6.8 3.4 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) Metallophos PF00149.23 EGG06288.1 - 2e-12 46.9 0.1 1.3e-11 44.2 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.6 EGG06288.1 - 0.0031 15.6 0.0 0.0082 14.2 0.0 1.6 2 0 0 2 2 2 1 Firmicute fructose-1,6-bisphosphatase Metallophos_2 PF12850.2 EGG06288.1 - 0.0034 17.2 0.0 0.01 15.6 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NSP2-B_epitope PF14757.1 EGG06288.1 - 0.0094 15.4 0.4 0.014 14.8 0.2 1.2 1 0 0 1 1 1 1 Immunogenic region of nsp2 protein of arterivirus polyprotein DUF3844 PF12955.2 EGG06291.1 - 2.6e-27 94.9 5.5 3.6e-27 94.4 3.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 EGG06291.1 - 7.8 6.7 12.8 35 4.6 8.9 2.0 1 1 0 1 1 1 0 EGF-like domain UCH PF00443.24 EGG06293.1 - 8.3e-79 264.4 0.0 3.8e-78 262.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGG06293.1 - 1.9e-19 70.2 2.5 5.2e-09 35.9 0.0 3.0 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EGG06293.1 - 3.5e-15 56.2 0.1 3.5e-15 56.2 0.0 2.6 2 0 0 2 2 2 1 DUSP domain ubiquitin PF00240.18 EGG06293.1 - 0.053 12.9 0.1 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family zf-FPG_IleRS PF06827.9 EGG06293.1 - 2.5 7.8 6.4 2.3 7.9 0.1 2.9 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS SpvD PF05563.7 EGG06296.1 - 0.043 13.3 0.3 0.12 11.8 0.2 1.7 1 1 0 1 1 1 0 Salmonella plasmid virulence protein SpvD DUF2360 PF10152.4 EGG06296.1 - 0.32 11.2 7.9 0.15 12.3 3.5 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) MFS_1 PF07690.11 EGG06299.1 - 0.00083 18.1 5.2 0.001 17.8 3.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TraY PF05509.6 EGG06301.1 - 0.058 13.1 0.7 33 4.3 0.0 3.2 3 0 0 3 3 3 0 TraY domain MFS_1 PF07690.11 EGG06302.1 - 0.00019 20.2 4.7 0.00028 19.7 3.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1275 PF06912.6 EGG06302.1 - 0.036 13.2 1.4 0.1 11.7 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) Acyl_transf_3 PF01757.17 EGG06302.1 - 0.15 10.8 5.8 0.24 10.1 4.0 1.3 1 0 0 1 1 1 0 Acyltransferase family NdhL PF10716.4 EGG06302.1 - 8.5 6.2 8.4 6.6 6.5 0.3 2.8 3 0 0 3 3 3 0 NADH dehydrogenase transmembrane subunit DUF1675 PF07897.6 EGG06304.1 - 8.2 6.2 31.9 0.56 10.0 6.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) PspC PF04024.7 EGG06306.1 - 0.034 13.6 0.0 0.08 12.4 0.0 1.6 1 0 0 1 1 1 0 PspC domain Tim17 PF02466.14 EGG06307.1 - 5.6e-21 74.9 17.0 5.9e-20 71.6 11.8 2.1 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family adh_short PF00106.20 EGG06309.1 - 1.2e-24 87.1 0.2 1.7e-24 86.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG06309.1 - 1.3e-10 41.2 0.1 2.2e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGG06309.1 - 5.8e-09 36.0 0.0 8.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGG06309.1 - 0.00072 19.6 0.1 0.002 18.1 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Pyr_redox PF00070.22 EGG06309.1 - 0.0063 16.8 0.0 0.02 15.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EGG06309.1 - 0.0079 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EGG06309.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EGG06309.1 - 0.024 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 EGG06309.1 - 0.032 14.6 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.14 EGG06309.1 - 0.064 12.2 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EGG06309.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA BLVR PF06375.6 EGG06310.1 - 0.0099 15.7 9.8 0.013 15.3 6.8 1.2 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) Vfa1 PF08432.5 EGG06310.1 - 0.019 15.0 4.5 0.019 14.9 3.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SPT6_acidic PF14632.1 EGG06310.1 - 0.077 13.1 12.8 0.13 12.4 8.9 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 TFIIF_alpha PF05793.7 EGG06310.1 - 0.18 10.1 15.1 0.21 9.9 10.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FLO_LFY PF01698.11 EGG06310.1 - 0.78 8.5 4.6 0.94 8.2 3.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 EGG06310.1 - 1.5 6.7 7.0 1.5 6.7 4.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EGG06310.1 - 1.7 7.9 10.5 2.1 7.6 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 EGG06310.1 - 2.7 7.8 6.8 3.4 7.5 4.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 OTU PF02338.14 EGG06311.1 - 0.0033 17.9 0.1 0.013 16.0 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease FAR1 PF03101.10 EGG06311.1 - 0.034 14.6 0.4 0.16 12.5 0.3 2.1 1 1 0 1 1 1 0 FAR1 DNA-binding domain Ribosomal_L37e PF01907.14 EGG06313.1 - 8.9e-27 92.6 15.8 1.6e-26 91.8 11.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EGG06313.1 - 0.0032 17.2 3.4 0.0049 16.6 2.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 EGG06313.1 - 0.017 14.8 0.9 0.019 14.6 0.6 1.3 1 1 0 1 1 1 0 SelR domain HypA PF01155.14 EGG06313.1 - 0.13 11.9 1.3 0.17 11.5 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 EGG06313.1 - 0.53 9.8 2.8 15 5.1 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGG06313.1 - 0.57 9.4 4.2 3.3 7.0 0.6 2.0 1 1 2 3 3 3 0 zinc-ribbon domain Ribosomal_S14 PF00253.16 EGG06313.1 - 1.4 8.3 9.3 4.4 6.7 0.4 2.5 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e zf-C3HC4 PF00097.20 EGG06313.1 - 1.8 8.3 5.1 2.8 7.6 3.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG06313.1 - 1.9 8.5 5.4 3 7.9 3.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DEADboxA PF12343.3 EGG06313.1 - 2.7 8.2 6.0 2 8.7 2.7 1.9 1 1 1 2 2 2 0 Cold shock protein DEAD box A An_peroxidase PF03098.10 EGG06315.1 - 2.1e-55 188.1 0.0 5e-54 183.5 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase Kinesin-relat_1 PF12711.2 EGG06315.1 - 0.13 12.7 1.6 0.45 10.9 0.1 2.6 3 0 0 3 3 3 0 Kinesin motor AAA_33 PF13671.1 EGG06316.1 - 7.1e-16 58.3 0.4 3.4e-15 56.1 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGG06316.1 - 0.00079 19.5 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGG06316.1 - 0.0013 17.8 0.0 0.0028 16.7 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EGG06316.1 - 0.0016 19.2 0.0 0.0023 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EGG06316.1 - 0.021 14.7 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase tRNA_lig_kinase PF08303.6 EGG06316.1 - 0.028 14.2 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 tRNA ligase kinase domain AAA_29 PF13555.1 EGG06316.1 - 0.028 13.9 0.1 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EGG06316.1 - 0.028 14.6 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 EGG06316.1 - 0.046 12.6 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 EGG06316.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGG06316.1 - 0.12 12.2 0.3 0.17 11.7 0.2 1.4 1 1 0 1 1 1 0 Dynamin family Neuropeptide_S PF14993.1 EGG06318.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Neuropeptide S precursor protein HECT PF00632.20 EGG06319.1 - 1.3e-79 267.6 0.0 3.1e-79 266.4 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 EGG06319.1 - 1.6e-05 24.5 0.4 0.11 12.3 0.0 4.1 2 1 1 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGG06319.1 - 0.013 15.7 2.1 0.049 13.9 0.1 3.2 3 0 0 3 3 3 0 HEAT repeats Adaptin_N PF01602.15 EGG06319.1 - 0.06 11.6 1.7 0.12 10.6 0.1 2.0 2 0 0 2 2 2 0 Adaptin N terminal region RIX1 PF08167.7 EGG06319.1 - 0.069 12.8 3.5 0.1 12.2 0.1 2.9 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Methyltransf_12 PF08242.7 EGG06320.1 - 2.4e-13 50.4 0.0 1.2e-12 48.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG06320.1 - 2.3e-09 37.0 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG06320.1 - 1.2e-08 35.3 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG06320.1 - 3.7e-08 33.2 0.0 5.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG06320.1 - 4.9e-08 33.5 0.0 1e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG06320.1 - 9.3e-08 32.3 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EGG06320.1 - 1.9e-06 27.0 0.0 0.039 12.9 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 EGG06320.1 - 0.00033 20.6 0.0 0.00059 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EGG06320.1 - 0.0022 18.8 0.0 0.022 15.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DUF3419 PF11899.3 EGG06320.1 - 0.0028 16.4 0.0 0.0063 15.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3419) Ubie_methyltran PF01209.13 EGG06320.1 - 0.0083 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGG06320.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.10 EGG06320.1 - 0.019 14.5 0.0 0.27 10.8 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase She9_MDM33 PF05546.6 EGG06321.1 - 1.7e-61 207.4 7.5 1.7e-61 207.4 5.2 1.5 1 1 0 1 1 1 1 She9 / Mdm33 family Put_Phosphatase PF06888.7 EGG06321.1 - 0.047 12.8 1.4 0.98 8.5 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase Pheromone PF08015.6 EGG06321.1 - 4.9 8.0 9.8 1.2 9.9 0.4 2.9 1 1 1 2 2 2 0 Fungal mating-type pheromone Radical_SAM PF04055.16 EGG06322.1 - 9.7e-24 84.4 0.0 3.4e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.7 EGG06322.1 - 5.7e-23 80.7 0.0 1.4e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EGG06322.1 - 9.1e-12 45.1 0.0 1.7e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin GTP_EFTU PF00009.22 EGG06322.1 - 0.01 15.2 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cNMP_binding PF00027.24 EGG06323.1 - 3.3e-39 132.5 0.0 2.5e-16 59.2 0.0 4.6 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 EGG06323.1 - 1.1e-18 67.9 4.0 9.1e-12 45.3 1.9 2.9 2 0 0 2 2 2 2 Patatin-like phospholipase Cys_Met_Meta_PP PF01053.15 EGG06326.1 - 2e-31 108.6 0.0 3e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGG06326.1 - 0.00011 21.2 0.0 0.00027 20.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II An_peroxidase PF03098.10 EGG06327.1 - 2.3e-59 201.2 0.0 8.1e-59 199.3 0.0 1.8 1 1 0 1 1 1 1 Animal haem peroxidase HEAT_EZ PF13513.1 EGG06329.1 - 1.1e-27 95.7 10.4 1.2e-10 41.5 0.0 10.8 11 1 1 12 12 12 4 HEAT-like repeat HEAT_2 PF13646.1 EGG06329.1 - 3.4e-24 84.9 2.5 8.9e-09 35.5 0.0 7.4 6 3 2 8 8 7 4 HEAT repeats HEAT PF02985.17 EGG06329.1 - 5.7e-20 69.5 15.9 0.00012 21.8 0.0 11.8 13 0 0 13 13 12 5 HEAT repeat Vac14_Fab1_bd PF12755.2 EGG06329.1 - 3e-09 37.1 0.0 0.0072 16.6 0.0 5.4 7 0 0 7 7 7 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EGG06329.1 - 1.2e-06 28.1 0.2 5.5 6.9 0.0 6.1 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 EGG06329.1 - 2.5e-06 27.3 0.4 2e-05 24.4 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain UME PF08064.8 EGG06329.1 - 1.9e-05 24.5 0.6 1.7 8.6 0.0 5.9 5 1 2 7 7 7 2 UME (NUC010) domain Ipi1_N PF12333.3 EGG06329.1 - 2.2e-05 24.3 0.0 0.19 11.6 0.0 5.5 5 1 1 6 6 6 1 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.15 EGG06329.1 - 2.4e-05 22.9 0.7 0.01 14.1 0.0 3.7 3 2 2 5 5 5 1 Adaptin N terminal region CLASP_N PF12348.3 EGG06329.1 - 3.1e-05 23.4 0.0 0.068 12.5 0.0 4.3 4 0 0 4 4 4 1 CLASP N terminal NfI_DNAbd_pre-N PF10524.4 EGG06329.1 - 0.013 15.0 2.0 6 6.5 0.0 4.1 4 0 0 4 4 4 0 Nuclear factor I protein pre-N-terminus ArgJ PF01960.13 EGG06331.1 - 1.1e-127 425.7 0.2 1.3e-127 425.3 0.1 1.0 1 0 0 1 1 1 1 ArgJ family UPF0086 PF01868.11 EGG06333.1 - 9.8e-05 21.9 0.1 0.0015 18.0 0.1 2.1 1 1 1 2 2 2 1 Domain of unknown function UPF0086 Paf1 PF03985.8 EGG06334.1 - 3.1e-36 125.0 0.0 5.5e-36 124.2 0.0 1.4 1 1 0 1 1 1 1 Paf1 CRCB PF02537.10 EGG06335.1 - 3.7e-31 107.4 12.7 2.2e-17 62.9 1.6 2.3 2 0 0 2 2 2 2 CrcB-like protein Sec3_C PF09763.4 EGG06336.1 - 1.9e-147 492.3 2.3 2.6e-147 491.9 1.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EGG06336.1 - 3.9e-20 71.5 0.0 9.4e-20 70.2 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 EGG06336.1 - 3.2e-07 29.2 0.3 1.1e-06 27.4 0.3 1.8 2 0 0 2 2 2 1 Vps52 / Sac2 family OPT PF03169.10 EGG06337.1 - 1.8e-127 426.4 35.9 1.2e-126 423.6 24.9 2.2 1 1 0 1 1 1 1 OPT oligopeptide transporter protein GFO_IDH_MocA_C PF02894.12 EGG06339.1 - 0.03 14.1 0.2 0.035 13.9 0.2 1.1 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain VHS PF00790.14 EGG06341.1 - 7.1e-33 113.2 1.1 9.5e-33 112.7 0.1 1.7 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.23 EGG06341.1 - 6e-16 57.5 0.5 1.6e-15 56.2 0.3 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGG06341.1 - 6.5e-16 57.6 1.9 8.9e-16 57.2 0.3 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EGG06341.1 - 5.1e-14 51.4 1.6 1.3e-13 50.1 0.1 2.4 3 0 0 3 3 3 1 Variant SH3 domain GAT PF03127.9 EGG06341.1 - 1.4e-06 28.2 2.3 4.2e-06 26.6 1.6 1.7 1 0 0 1 1 1 1 GAT domain U3snoRNP10 PF12397.3 EGG06341.1 - 0.23 11.4 0.7 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 Syntaxin_2 PF14523.1 EGG06341.1 - 5.6 7.0 9.6 3.5 7.7 1.9 2.4 2 0 0 2 2 2 0 Syntaxin-like protein NAD_binding_6 PF08030.7 EGG06344.1 - 1.2e-33 116.2 0.0 2.3e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGG06344.1 - 5.2e-22 77.7 0.0 1.1e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGG06344.1 - 5.4e-14 52.3 10.8 5.4e-14 52.3 7.5 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGG06344.1 - 0.00061 19.8 0.0 0.0019 18.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGG06344.1 - 0.037 14.5 0.0 0.14 12.7 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DnaI_N PF07319.6 EGG06345.1 - 0.068 13.4 0.4 0.21 11.8 0.3 1.9 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus ClpB_D2-small PF10431.4 EGG06345.1 - 0.2 11.5 0.7 0.69 9.8 0.1 2.1 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein HTH_33 PF13592.1 EGG06347.1 - 0.26 10.8 2.0 1.8 8.1 0.1 2.8 3 0 0 3 3 3 0 Winged helix-turn helix PHP PF02811.14 EGG06347.1 - 0.27 11.0 2.0 0.4 10.4 1.2 1.5 1 1 0 1 1 1 0 PHP domain HD_assoc PF13286.1 EGG06348.1 - 0.06 13.6 0.3 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Phosphohydrolase-associated domain DUF2205 PF10224.4 EGG06349.1 - 0.026 14.0 0.2 0.072 12.6 0.0 1.8 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) ING PF12998.2 EGG06350.1 - 0.032 14.5 0.2 0.066 13.4 0.1 1.4 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding ATP-synt_DE PF00401.15 EGG06352.1 - 4.6 7.1 9.0 9.1 6.2 0.2 2.6 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF4110 PF13422.1 EGG06354.1 - 0.15 11.9 1.8 0.29 11.0 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) CRAL_TRIO PF00650.15 EGG06356.1 - 7.8e-33 113.2 0.1 1.3e-32 112.5 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EGG06356.1 - 4.6e-10 39.5 0.1 9.4e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGG06356.1 - 1.7e-06 28.0 0.0 4.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Nop14 PF04147.7 EGG06357.1 - 0.16 9.8 13.6 0.18 9.6 9.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF605 PF04652.11 EGG06357.1 - 1.6 8.0 32.4 2.1 7.6 22.4 1.1 1 0 0 1 1 1 0 Vta1 like DUF3463 PF11946.3 EGG06360.1 - 0.083 12.4 1.1 0.15 11.6 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) YodA PF09223.6 EGG06361.1 - 0.07 12.7 0.3 0.073 12.7 0.2 1.0 1 0 0 1 1 1 0 YodA lipocalin-like domain CTP_synth_N PF06418.9 EGG06363.1 - 2.6e-117 390.8 0.0 3.4e-117 390.4 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EGG06363.1 - 6.9e-49 165.9 0.0 1e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CbiA PF01656.18 EGG06363.1 - 0.00029 20.2 0.0 0.00075 18.9 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_C26 PF07722.8 EGG06363.1 - 0.0014 18.1 0.0 0.0035 16.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 ArsA_ATPase PF02374.10 EGG06363.1 - 0.2 10.6 0.3 0.3 10.0 0.2 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase zf-RING_2 PF13639.1 EGG06364.1 - 0.0011 18.7 10.8 0.0011 18.7 7.5 2.1 2 0 0 2 2 2 1 Ring finger domain LrgB PF04172.11 EGG06365.1 - 9.7e-22 77.1 9.3 9.5e-21 73.9 6.5 2.3 1 1 0 1 1 1 1 LrgB-like family RRM_1 PF00076.17 EGG06367.1 - 2.2e-21 75.2 0.0 2.2e-16 59.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG06367.1 - 8.2e-15 54.5 0.0 1.8e-12 47.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG06367.1 - 3e-10 39.8 0.0 1.5e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-4B PF06273.6 EGG06369.1 - 4.4 5.9 9.1 7 5.2 6.3 1.3 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B bZIP_1 PF00170.16 EGG06370.1 - 8.4e-09 35.2 6.6 8.4e-09 35.2 4.6 3.1 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EGG06370.1 - 2.5e-08 33.6 6.0 2.5e-08 33.6 4.2 3.4 3 0 0 3 3 3 2 Basic region leucine zipper bZIP_Maf PF03131.12 EGG06370.1 - 0.0025 18.0 1.7 0.0025 18.0 1.2 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF4634 PF15465.1 EGG06370.1 - 0.11 12.6 0.2 0.32 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) Gal4_dimer PF03902.8 EGG06370.1 - 0.26 11.2 2.1 0.47 10.4 0.7 2.0 2 0 0 2 2 2 0 Gal4-like dimerisation domain DUF3368 PF11848.3 EGG06371.1 - 0.12 11.9 0.1 66 3.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) GCR1_C PF12550.3 EGG06371.1 - 0.32 10.9 2.4 4.9 7.0 0.0 3.3 4 0 0 4 4 4 0 Transcriptional activator of glycolytic enzymes DUF599 PF04654.7 EGG06371.1 - 0.46 9.6 3.7 6.2 5.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF599 Clp1 PF06807.9 EGG06374.1 - 6.2e-11 42.4 0.0 5.5e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EGG06374.1 - 6.4e-06 25.9 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EGG06374.1 - 0.00052 19.9 0.0 0.0021 17.9 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGG06374.1 - 0.00071 19.6 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EGG06374.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family ArgK PF03308.11 EGG06374.1 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_22 PF13401.1 EGG06374.1 - 0.0025 17.9 0.0 0.0066 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG06374.1 - 0.0042 17.8 0.1 0.014 16.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EGG06374.1 - 0.0069 16.1 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase ATP_bind_1 PF03029.12 EGG06374.1 - 0.0072 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EGG06374.1 - 0.0089 16.3 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.7 EGG06374.1 - 0.017 14.8 0.0 0.048 13.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EGG06374.1 - 0.027 14.6 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EGG06374.1 - 0.029 13.5 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EGG06374.1 - 0.041 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain CbiA PF01656.18 EGG06374.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 EGG06374.1 - 0.12 11.9 0.1 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EGG06374.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EGG06374.1 - 0.15 10.8 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ARS2 PF04959.8 EGG06376.1 - 4.3e-13 49.9 1.3 2e-12 47.7 0.0 2.8 2 1 1 3 3 3 1 Arsenite-resistance protein 2 DUF3546 PF12066.3 EGG06376.1 - 4.9e-13 49.0 0.9 1.3e-12 47.7 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 EGG06376.1 - 2.3e-05 23.8 5.8 2.3e-05 23.8 4.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) RRM_1 PF00076.17 EGG06376.1 - 8.7e-05 22.0 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.2 EGG06376.1 - 0.76 9.9 4.5 0.7 10.0 0.3 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Kinesin PF00225.18 EGG06377.1 - 3.5e-111 371.1 0.6 1.3e-110 369.2 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 EGG06377.1 - 8.3e-30 103.2 0.1 3.9e-29 101.0 0.0 2.3 3 0 0 3 3 3 1 Kinesin protein PH PF00169.24 EGG06377.1 - 1.9e-12 47.2 0.1 6.4e-12 45.5 0.1 1.9 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 EGG06377.1 - 6.5e-08 32.4 0.2 1.6e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 EGG06377.1 - 1.2e-07 31.7 0.1 1.8e-06 27.9 0.0 3.1 3 0 0 3 3 3 1 FHA domain PH_9 PF15410.1 EGG06377.1 - 0.0035 17.4 0.4 0.022 14.9 0.3 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain E1-E2_ATPase PF00122.15 EGG06378.1 - 1.9e-53 180.8 7.6 1.9e-53 180.8 5.3 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGG06378.1 - 1.1e-39 135.8 5.1 1.1e-39 135.8 3.6 3.1 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGG06378.1 - 1.3e-30 107.4 0.0 6.6e-29 101.8 0.0 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGG06378.1 - 4e-17 61.9 0.1 8.7e-17 60.8 0.1 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGG06378.1 - 1.1e-12 48.5 0.1 6.8e-12 45.9 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGG06378.1 - 3.6e-12 45.5 0.1 1e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGG06378.1 - 5.6e-06 26.1 0.4 2.9e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Mito_fiss_reg PF05308.6 EGG06379.1 - 0.018 14.4 0.2 0.02 14.2 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator HCR PF07111.7 EGG06379.1 - 0.038 12.0 1.4 0.043 11.8 1.0 1.0 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) KxDL PF10241.4 EGG06379.1 - 0.059 13.2 0.3 0.065 13.1 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein MCM2_N PF12619.3 EGG06382.1 - 5.2 7.0 6.4 3.4 7.6 1.2 2.1 1 1 1 2 2 2 0 Mini-chromosome maintenance protein 2 F-box-like PF12937.2 EGG06383.1 - 0.014 15.1 0.0 0.041 13.5 0.0 1.9 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 EGG06383.1 - 2.2 7.9 7.8 0.76 9.4 0.4 3.4 1 1 4 5 5 5 0 Leucine Rich repeats (2 copies) NTR2 PF15458.1 EGG06384.1 - 9.1e-33 113.5 7.6 9.1e-33 113.5 5.2 2.9 4 0 0 4 4 4 1 Nineteen complex-related protein 2 PROCT PF08084.6 EGG06384.1 - 0.022 14.4 0.0 0.44 10.2 0.0 2.5 2 0 0 2 2 2 0 PROCT (NUC072) domain Anoctamin PF04547.7 EGG06384.1 - 0.1 11.2 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 Calcium-activated chloride channel dCMP_cyt_deam_1 PF00383.17 EGG06385.1 - 2.5e-20 72.0 0.0 3.4e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EGG06385.1 - 0.0003 20.6 1.1 0.055 13.3 0.8 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 EGG06385.1 - 0.0049 16.5 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain MafB19-deam PF14437.1 EGG06385.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 1 0 1 1 1 0 MafB19-like deaminase TAF4 PF05236.9 EGG06386.1 - 5.7e-09 35.6 0.3 1.3e-08 34.4 0.2 1.6 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TAF4 PF05236.9 EGG06387.1 - 3.8e-07 29.6 8.1 3.8e-07 29.6 5.6 2.9 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family bZIP_C PF12498.3 EGG06387.1 - 5.9 8.1 11.4 0.15 13.2 2.0 2.3 2 1 1 3 3 3 0 Basic leucine-zipper C terminal Longin PF13774.1 EGG06389.1 - 2e-28 97.7 0.2 3.5e-28 96.9 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EGG06389.1 - 2.6e-14 52.5 0.1 4.7e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Synaptobrevin DUF3664 PF12406.3 EGG06390.1 - 0.26 11.8 8.2 0.91 10.1 3.9 2.4 2 0 0 2 2 2 0 Surface protein Maf1 PF09174.5 EGG06391.1 - 1.4e-35 122.7 4.7 1.1e-27 97.0 0.2 2.9 3 0 0 3 3 3 2 Maf1 regulator Myb_DNA-binding PF00249.26 EGG06392.1 - 1.1e-15 57.4 2.7 1.3e-11 44.3 1.2 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGG06392.1 - 2.3e-13 50.0 0.2 1e-10 41.5 0.1 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGG06392.1 - 0.0053 16.8 0.7 0.24 11.5 0.3 2.3 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EGG06392.1 - 0.049 13.8 0.2 0.29 11.3 0.1 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like zf-CCCH PF00642.19 EGG06393.1 - 1.4e-06 27.8 1.3 1.4e-06 27.8 0.9 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Atrophin-1 PF03154.10 EGG06393.1 - 3.8 5.5 6.5 5.8 4.9 4.5 1.2 1 0 0 1 1 1 0 Atrophin-1 family Peptidase_M24 PF00557.19 EGG06394.1 - 1.1e-52 178.6 0.0 1.5e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGG06394.1 - 3.2e-12 45.9 0.0 7.8e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain AA_permease PF00324.16 EGG06395.1 - 4e-110 368.4 36.4 4.6e-110 368.1 25.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGG06395.1 - 3.2e-30 105.0 41.1 3.8e-30 104.7 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease Rav1p_C PF12234.3 EGG06396.1 - 4.1e-62 210.2 0.0 2.7e-44 151.4 0.0 2.1 1 1 1 2 2 2 2 RAVE protein 1 C terminal AA_permease PF00324.16 EGG06397.1 - 3.7e-104 348.7 35.0 4.4e-104 348.4 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGG06397.1 - 2.8e-25 88.7 39.7 3.5e-25 88.4 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease MBOAT_2 PF13813.1 EGG06401.1 - 2.9e-09 36.8 3.9 3.4e-08 33.4 0.6 2.9 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family EPSP_synthase PF00275.15 EGG06402.1 - 2.6e-113 378.6 0.0 4e-113 378.0 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EGG06402.1 - 1.9e-101 338.3 0.0 4.2e-101 337.2 0.0 1.6 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EGG06402.1 - 6.8e-63 212.3 0.0 1.1e-62 211.6 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EGG06402.1 - 4.6e-30 104.5 0.0 2.4e-29 102.2 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EGG06402.1 - 9.9e-24 83.2 0.0 2.2e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EGG06402.1 - 2.7e-18 66.3 0.0 8.7e-16 58.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EGG06402.1 - 4.5e-08 32.7 0.0 9.6e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EGG06402.1 - 6.9e-05 21.6 0.5 0.0003 19.5 0.1 2.1 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EGG06402.1 - 0.0015 19.3 0.0 0.0037 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGG06402.1 - 0.023 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Saccharop_dh PF03435.13 EGG06402.1 - 0.048 12.6 0.0 0.084 11.8 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase ThiF PF00899.16 EGG06402.1 - 0.051 13.4 0.2 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 ThiF family F420_oxidored PF03807.12 EGG06402.1 - 0.052 13.9 0.1 0.14 12.6 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent JAB PF01398.16 EGG06403.1 - 7.8e-30 102.9 0.1 1.6e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EGG06403.1 - 9.5e-07 28.3 0.0 2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Sugar_tr PF00083.19 EGG06406.1 - 2.9e-88 296.4 18.8 3.4e-88 296.2 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG06406.1 - 2.5e-17 62.6 44.7 3e-16 59.1 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sporozoite_P67 PF05642.6 EGG06408.1 - 0.19 9.5 1.3 0.22 9.3 0.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cytochrom_B561 PF03188.11 EGG06411.1 - 6.4e-10 39.0 10.4 6.4e-10 39.0 7.2 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EGG06411.1 - 0.0094 15.5 6.8 0.015 14.8 3.7 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.12 EGG06411.1 - 0.0095 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 DOMON domain Claudin_2 PF13903.1 EGG06411.1 - 1.4 8.5 9.4 5.5 6.6 6.6 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pkinase PF00069.20 EGG06412.1 - 1e-16 60.8 0.0 1.3e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG06412.1 - 7.6e-10 38.2 0.0 1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG06412.1 - 0.008 15.9 0.2 0.028 14.1 0.3 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGG06412.1 - 0.083 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 RIO1 family PRP38_assoc PF12871.2 EGG06413.1 - 0.00033 21.1 23.1 0.00033 21.1 16.0 2.5 3 0 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Pap_E4 PF02711.9 EGG06416.1 - 9.8 7.0 14.4 0.81 10.5 3.5 3.0 2 0 0 2 2 2 0 E4 protein MIF4G_like PF09088.6 EGG06417.1 - 6.3e-54 182.3 0.0 2e-53 180.6 0.0 1.9 2 1 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 EGG06417.1 - 4.8e-29 101.3 19.9 7.4e-27 94.1 12.9 3.2 2 1 0 2 2 2 1 MIF4G like Borrelia_P83 PF05262.6 EGG06420.1 - 3.7 5.7 16.1 4.3 5.4 11.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein HSP70 PF00012.15 EGG06421.1 - 2.4e-260 864.6 12.3 2.7e-260 864.4 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGG06421.1 - 7.5e-18 64.2 0.6 4.6e-16 58.3 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 EGG06421.1 - 0.0018 17.1 0.4 0.08 11.7 0.2 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EGG06421.1 - 0.013 14.6 0.2 0.013 14.6 0.1 2.6 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase Sad1_UNC PF07738.8 EGG06424.1 - 8.5e-28 96.8 0.0 1.1e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal FGGY_C PF02782.11 EGG06425.1 - 7.9e-43 146.3 0.0 1.1e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGG06425.1 - 6.3e-25 87.8 0.0 2.2e-24 86.1 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EGG06425.1 - 2.1e-06 27.2 0.1 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family UPF0075 PF03702.9 EGG06425.1 - 0.067 12.0 0.1 0.12 11.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) ROK PF00480.15 EGG06425.1 - 0.094 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 ROK family Thioredoxin PF00085.15 EGG06426.1 - 3.2e-45 152.0 0.2 3.2e-21 74.9 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EGG06426.1 - 1.4e-13 51.0 0.0 1.2e-08 35.0 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EGG06426.1 - 1.1e-07 32.0 1.2 7e-06 26.2 0.0 3.6 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGG06426.1 - 1.5e-06 28.1 0.2 0.033 14.2 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EGG06426.1 - 0.0013 18.7 0.3 0.033 14.1 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 EGG06426.1 - 0.012 15.2 0.1 1.4 8.5 0.0 2.8 3 0 0 3 3 3 0 AhpC/TSA family Thioredoxin_9 PF14595.1 EGG06426.1 - 0.059 12.9 0.0 0.36 10.4 0.0 2.3 3 0 0 3 3 3 0 Thioredoxin TPR_11 PF13414.1 EGG06427.1 - 2.6e-25 87.8 23.2 0.0012 18.4 0.0 9.7 9 0 0 9 9 9 7 TPR repeat TPR_2 PF07719.12 EGG06427.1 - 1.1e-19 68.7 22.1 0.053 13.4 0.0 12.4 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGG06427.1 - 2.1e-18 66.0 23.0 1.1e-06 28.4 0.0 9.3 9 1 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.23 EGG06427.1 - 2.1e-17 61.9 12.3 0.0054 16.2 0.0 10.4 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGG06427.1 - 1.1e-15 57.7 40.0 0.00011 22.7 0.0 11.4 9 3 3 13 13 13 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGG06427.1 - 8.8e-15 54.7 26.3 0.00038 20.7 0.1 9.8 9 3 3 12 12 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGG06427.1 - 1.2e-13 49.8 2.0 0.13 12.0 0.0 9.2 10 0 0 10 10 9 2 Tetratricopeptide repeat Apc3 PF12895.2 EGG06427.1 - 6.8e-10 38.9 9.5 0.0047 17.0 0.0 6.0 4 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EGG06427.1 - 2.2e-09 36.9 9.6 0.31 11.0 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGG06427.1 - 1.4e-08 33.9 9.3 0.068 12.9 0.0 9.5 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGG06427.1 - 1.8e-07 31.1 43.2 0.039 14.5 0.0 12.3 11 4 3 15 15 12 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGG06427.1 - 1.3e-06 28.1 9.9 12 6.3 0.0 9.9 11 1 1 12 12 11 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGG06427.1 - 1.9e-05 24.8 27.1 0.027 14.9 0.0 11.8 12 1 0 12 12 11 1 Tetratricopeptide repeat TPR_4 PF07721.9 EGG06427.1 - 0.0017 18.5 1.6 0.44 11.1 0.1 5.0 6 0 0 6 6 3 1 Tetratricopeptide repeat TPPII_N PF12583.3 EGG06427.1 - 0.0043 17.1 0.4 1.4 9.0 0.0 4.2 3 0 0 3 3 3 1 Tripeptidyl peptidase II N terminal PH_9 PF15410.1 EGG06428.1 - 3.6e-05 23.8 0.0 7.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGG06428.1 - 0.0002 21.4 0.0 0.0024 18.0 0.0 2.3 2 0 0 2 2 2 1 PH domain LRR_4 PF12799.2 EGG06429.1 - 4.8 6.9 13.0 0.75 9.4 0.1 4.7 7 1 0 7 7 7 0 Leucine Rich repeats (2 copies) Glyco_hydro_18 PF00704.23 EGG06430.1 - 3.4e-50 171.4 7.2 4.8e-40 138.0 1.6 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 Peptidase_S9_N PF02897.10 EGG06431.1 - 7.5e-95 317.9 0.1 1.1e-94 317.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 EGG06431.1 - 2.4e-63 213.2 0.0 3.9e-63 212.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGG06431.1 - 0.027 14.2 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.7 EGG06431.1 - 0.042 12.3 0.0 0.074 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EGG06431.1 - 0.043 13.3 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold GDI PF00996.13 EGG06433.1 - 1.3e-27 96.2 0.1 2.1e-27 95.5 0.1 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor TIP49 PF06068.8 EGG06434.1 - 1.3e-180 600.4 0.1 2.5e-180 599.4 0.1 1.4 1 1 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EGG06434.1 - 5.8e-11 42.7 0.1 1.6e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGG06434.1 - 1.6e-10 40.4 0.0 2.4e-06 26.7 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGG06434.1 - 1.4e-05 25.2 0.4 0.17 12.0 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EGG06434.1 - 2.5e-05 24.3 0.0 0.0022 18.0 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGG06434.1 - 3.7e-05 23.3 0.0 0.00013 21.6 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EGG06434.1 - 0.00012 22.0 0.1 0.0008 19.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGG06434.1 - 0.00093 18.9 0.1 0.096 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EGG06434.1 - 0.001 18.4 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGG06434.1 - 0.0044 16.4 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGG06434.1 - 0.0058 15.7 0.1 0.012 14.6 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EGG06434.1 - 0.0075 15.7 0.3 5.3 6.4 0.0 2.7 3 0 0 3 3 3 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGG06434.1 - 0.0088 15.2 0.1 0.22 10.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EGG06434.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 EGG06434.1 - 0.044 13.6 0.0 8.2 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EGG06434.1 - 0.062 12.3 0.1 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 KaiC DnaB_C PF03796.10 EGG06434.1 - 0.082 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_33 PF13671.1 EGG06434.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTF2 PF02136.15 EGG06435.1 - 0.0062 16.8 0.1 0.0087 16.4 0.1 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF3231 PF11553.3 EGG06435.1 - 0.077 12.4 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) Peptidase_C3G PF12381.3 EGG06436.1 - 0.17 11.0 1.1 0.25 10.5 0.1 1.6 2 0 0 2 2 2 0 Tungro spherical virus-type peptidase IMPDH PF00478.20 EGG06437.1 - 6.2e-140 466.0 0.4 7.2e-140 465.8 0.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EGG06437.1 - 1.3e-10 40.8 0.0 3.7e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EGG06437.1 - 4.1e-10 39.3 3.8 3.7e-07 29.6 2.0 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EGG06437.1 - 1.9e-07 30.2 4.0 5.6e-07 28.7 2.7 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EGG06437.1 - 3.4e-06 26.5 2.6 1.6e-05 24.2 1.8 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 EGG06437.1 - 0.004 16.2 1.7 0.004 16.2 1.2 1.6 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 EGG06437.1 - 0.01 14.8 1.6 0.06 12.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Dus PF01207.12 EGG06437.1 - 0.021 13.6 0.2 0.38 9.5 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Response_reg PF00072.19 EGG06437.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Response regulator receiver domain EAL PF00563.15 EGG06437.1 - 0.076 12.4 0.1 0.75 9.2 0.0 2.0 2 0 0 2 2 2 0 EAL domain GDA1_CD39 PF01150.12 EGG06438.1 - 3.5e-98 328.9 0.0 4.3e-98 328.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EGG06438.1 - 0.061 12.5 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family OTU PF02338.14 EGG06439.1 - 0.0017 18.9 0.0 0.0035 17.9 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease zf-CCHC PF00098.18 EGG06440.1 - 0.22 11.5 4.0 0.33 10.9 2.8 1.3 1 0 0 1 1 1 0 Zinc knuckle Glyco_hydro_16 PF00722.16 EGG06441.1 - 1.4e-10 40.7 0.0 2.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1675 PF07897.6 EGG06442.1 - 0.019 14.8 6.4 0.025 14.4 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) O-FucT PF10250.4 EGG06443.1 - 5.9e-05 22.3 0.1 0.027 13.6 0.0 3.0 1 1 1 2 2 2 2 GDP-fucose protein O-fucosyltransferase SLAC1 PF03595.12 EGG06443.1 - 0.0047 15.6 0.1 0.007 15.0 0.1 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel HECT_2 PF09814.4 EGG06443.1 - 0.31 9.6 7.2 0.082 11.6 2.5 1.7 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding FAR1 PF03101.10 EGG06447.1 - 0.019 15.4 0.4 0.033 14.6 0.3 1.3 1 0 0 1 1 1 0 FAR1 DNA-binding domain DHC_N2 PF08393.8 EGG06449.1 - 0.0075 14.8 0.0 0.0082 14.6 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Metallophos PF00149.23 EGG06453.1 - 4.5e-42 143.7 1.3 5.7e-42 143.3 0.9 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2712 PF10916.3 EGG06454.1 - 0.13 12.2 1.0 0.26 11.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2712) Peptidase_M24 PF00557.19 EGG06457.1 - 8.5e-30 103.8 0.0 1.2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Chorismate_synt PF01264.16 EGG06459.1 - 1.9e-131 437.6 0.1 2.7e-131 437.1 0.0 1.2 1 0 0 1 1 1 1 Chorismate synthase Hormone_4 PF00220.12 EGG06459.1 - 0.12 12.0 1.5 0.3 10.8 1.0 1.7 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain NDUF_B8 PF05821.6 EGG06461.1 - 6.5e-10 38.9 0.0 8.3e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DPBB_1 PF03330.13 EGG06464.1 - 0.00054 19.9 0.1 0.00098 19.0 0.0 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGG06464.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Barwin family PRMT5 PF05185.11 EGG06465.1 - 2.6e-133 445.2 0.0 3.1e-122 408.7 0.0 2.2 1 1 1 2 2 2 2 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 EGG06465.1 - 0.036 14.6 0.0 0.097 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cpn60_TCP1 PF00118.19 EGG06466.1 - 1.3e-130 436.2 10.9 1.6e-130 436.0 7.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Transposase_23 PF03017.9 EGG06466.1 - 0.089 12.3 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 TNP1/EN/SPM transposase DUF3336 PF11815.3 EGG06467.1 - 9.7e-44 148.3 3.6 9.7e-44 148.3 2.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EGG06467.1 - 3.5e-20 72.8 0.1 6.7e-20 71.8 0.0 1.5 2 0 0 2 2 2 1 Patatin-like phospholipase Peptidase_S28 PF05577.7 EGG06468.1 - 0.046 12.2 1.0 0.065 11.7 0.7 1.3 1 1 0 1 1 1 0 Serine carboxypeptidase S28 YycI PF09648.5 EGG06468.1 - 0.054 12.9 0.5 0.098 12.0 0.3 1.4 1 0 0 1 1 1 0 YycH protein PALP PF00291.20 EGG06469.1 - 2.5e-61 207.5 0.0 3.1e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pyr_redox_2 PF07992.9 EGG06470.1 - 9.5e-28 97.4 0.1 1.4e-17 64.2 0.0 3.7 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGG06470.1 - 1.6e-11 44.4 0.1 7.6e-11 42.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGG06470.1 - 0.028 14.4 0.3 0.51 10.3 0.0 3.0 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase UbiA PF01040.13 EGG06471.1 - 5.4e-17 61.8 19.9 3.2e-16 59.3 13.1 2.5 1 1 1 2 2 2 1 UbiA prenyltransferase family SET PF00856.23 EGG06472.1 - 1.4e-15 57.9 0.0 5e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.11 EGG06472.1 - 3.6e-05 23.9 0.6 0.00014 22.0 0.2 2.1 2 1 0 2 2 2 1 Pre-SET motif tRNA_int_end_N2 PF12928.2 EGG06474.1 - 2.5e-12 46.0 0.0 1.8e-11 43.2 0.0 2.3 2 1 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EGG06474.1 - 0.015 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain DUF423 PF04241.10 EGG06475.1 - 0.93 9.4 3.5 0.32 10.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF423) MFS_1 PF07690.11 EGG06476.1 - 1.2e-18 66.9 62.9 1.6e-14 53.3 26.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PDT PF00800.13 EGG06478.1 - 3.7e-39 134.1 0.1 5.3e-39 133.6 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydratase GlyL_C PF12524.3 EGG06479.1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 dsDNA virus glycoprotein L C terminal Ras PF00071.17 EGG06480.1 - 0.086 12.2 0.0 0.094 12.1 0.0 1.1 1 0 0 1 1 1 0 Ras family DUF3500 PF12006.3 EGG06481.1 - 0.05 12.5 0.4 0.11 11.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3500) LTXXQ PF07813.7 EGG06481.1 - 0.27 11.6 4.3 2.1 8.8 0.0 3.3 1 1 1 2 2 2 0 LTXXQ motif family protein Actin PF00022.14 EGG06482.1 - 1.2e-87 293.9 0.0 1.5e-87 293.6 0.0 1.0 1 0 0 1 1 1 1 Actin Yae1_N PF09811.4 EGG06484.1 - 5.6e-13 48.1 3.5 8.9e-13 47.5 2.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RNA_pol_3_Rpc31 PF11705.3 EGG06485.1 - 9.3e-13 48.6 34.4 7.7e-12 45.6 23.8 2.5 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 HAND PF09110.6 EGG06485.1 - 0.1 13.0 5.4 0.14 12.5 3.7 1.2 1 0 0 1 1 1 0 HAND UMP1 PF05348.6 EGG06487.1 - 0.023 14.6 0.6 0.028 14.3 0.4 1.1 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 Remorin_C PF03763.8 EGG06487.1 - 0.34 10.4 6.5 0.43 10.1 4.5 1.2 1 0 0 1 1 1 0 Remorin, C-terminal region HMG_box PF00505.14 EGG06493.1 - 2.7e-15 56.3 3.3 5.9e-15 55.2 2.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGG06493.1 - 8.3e-09 35.6 3.5 2.1e-08 34.4 2.4 1.7 1 0 0 1 1 1 1 HMG-box domain AT_hook PF02178.14 EGG06493.1 - 0.11 12.2 3.9 0.47 10.2 2.7 2.2 1 0 0 1 1 1 0 AT hook motif Nucleoplasmin PF03066.10 EGG06493.1 - 0.32 10.4 0.0 0.32 10.4 0.0 3.0 2 1 0 2 2 2 0 Nucleoplasmin PPP4R2 PF09184.6 EGG06493.1 - 0.91 9.0 19.7 0.34 10.4 8.5 2.3 2 0 0 2 2 2 0 PPP4R2 Sugar_tr PF00083.19 EGG06494.1 - 2.3e-87 293.4 27.0 2.7e-87 293.2 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG06494.1 - 9.8e-16 57.3 41.8 3.1e-15 55.7 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily XPG_I PF00867.13 EGG06497.1 - 1.4e-28 98.8 0.0 2.7e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGG06497.1 - 7.9e-26 90.2 0.0 1.8e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EGG06497.1 - 5.3e-05 22.8 0.0 7.2e-05 22.3 0.0 1.3 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EGG06497.1 - 0.05 13.8 0.1 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold WD40 PF00400.27 EGG06499.1 - 1.4e-13 50.1 19.7 0.00059 19.6 0.2 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGG06499.1 - 0.17 10.1 0.1 1.9 6.6 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain AJAP1_PANP_C PF15298.1 EGG06500.1 - 0.014 15.2 2.6 0.023 14.5 1.8 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus GRAB PF10375.4 EGG06502.1 - 0.0077 15.8 0.9 0.0077 15.8 0.7 2.1 2 0 0 2 2 2 1 GRIP-related Arf-binding domain SNF2_N PF00176.18 EGG06503.1 - 1.3e-49 168.6 2.6 3.9e-28 98.1 0.2 2.0 1 1 1 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.10 EGG06503.1 - 0.001 18.9 0.2 0.014 15.2 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGG06503.1 - 0.014 14.8 0.1 2.6 7.4 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase Zot PF05707.7 EGG06503.1 - 0.023 14.1 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF2075 PF09848.4 EGG06503.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Nramp PF01566.13 EGG06505.1 - 9.5e-41 139.7 9.8 1.1e-28 100.0 4.4 2.9 1 1 1 2 2 2 2 Natural resistance-associated macrophage protein Glyco_hydro_12 PF01670.11 EGG06506.1 - 1.6e-16 60.5 0.0 2.7e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Nramp PF01566.13 EGG06507.1 - 1.7e-72 244.1 18.9 1.6e-71 241.0 13.1 2.1 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein ASFV_J13L PF05568.6 EGG06507.1 - 0.061 12.8 0.6 2.3 7.7 0.2 2.7 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF4519 PF15012.1 EGG06507.1 - 0.16 11.8 0.2 0.57 10.1 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DUF1510 PF07423.6 EGG06507.1 - 0.42 9.9 0.0 0.42 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SNF2_N PF00176.18 EGG06508.1 - 1.1e-69 234.4 0.0 2.1e-69 233.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGG06508.1 - 6.2e-13 48.4 0.0 1.4e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGG06508.1 - 3.1e-09 36.5 0.0 1.2e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 EGG06508.1 - 6.2e-08 32.5 11.9 6.2e-08 32.5 8.2 2.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG06508.1 - 7.4e-07 28.7 12.0 7.4e-07 28.7 8.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGG06508.1 - 1.8e-06 27.6 13.3 1.8e-06 27.6 9.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGG06508.1 - 4e-06 26.3 11.0 4e-06 26.3 7.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG06508.1 - 0.00014 21.4 11.2 0.00014 21.4 7.8 2.4 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EGG06508.1 - 0.00085 19.0 4.8 0.0019 17.9 3.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DEAD_2 PF06733.10 EGG06508.1 - 0.0014 18.0 0.1 0.05 13.0 0.0 2.6 2 0 0 2 2 2 1 DEAD_2 HDA2-3 PF11496.3 EGG06508.1 - 0.0014 17.4 0.0 0.048 12.4 0.0 2.6 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 zf-rbx1 PF12678.2 EGG06508.1 - 0.0023 17.9 5.1 0.0068 16.5 3.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGG06508.1 - 0.009 15.8 12.0 0.009 15.8 8.3 2.4 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGG06508.1 - 0.025 14.4 3.2 0.061 13.1 2.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EGG06508.1 - 1.9 8.0 8.7 4 7.0 6.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS91 PF14319.1 EGG06508.1 - 3 7.4 14.9 0.64 9.5 2.0 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-P11 PF03854.9 EGG06508.1 - 6.3 6.3 17.6 0.052 13.0 5.0 2.3 2 0 0 2 2 2 0 P-11 zinc finger DUF2956 PF11169.3 EGG06509.1 - 0.14 12.1 2.3 0.29 11.0 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) LRR_4 PF12799.2 EGG06510.1 - 1.5e-06 27.7 1.9 3.8e-06 26.3 1.3 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG06510.1 - 0.0001 21.9 2.3 0.00026 20.6 1.6 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 EGG06510.1 - 0.00082 19.0 9.2 0.13 12.3 0.3 3.4 3 0 0 3 3 2 2 Leucine Rich Repeat CENP-B_dimeris PF09026.5 EGG06510.1 - 0.0064 16.7 10.9 0.014 15.6 7.6 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain LRR_6 PF13516.1 EGG06510.1 - 0.011 15.7 3.1 0.74 10.0 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich repeat eIF-3c_N PF05470.7 EGG06510.1 - 0.011 13.8 3.2 0.2 9.7 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus LRR_7 PF13504.1 EGG06510.1 - 0.032 14.3 5.9 5.8 7.5 0.1 3.8 3 0 0 3 3 3 0 Leucine rich repeat Daxx PF03344.10 EGG06510.1 - 0.21 10.0 4.3 0.32 9.4 3.0 1.3 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 EGG06510.1 - 0.94 7.2 5.9 1.4 6.6 4.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 EGG06510.1 - 0.95 7.2 9.7 1.4 6.7 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EGG06510.1 - 1.6 7.3 19.1 3.1 6.4 13.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 EGG06510.1 - 1.8 7.4 4.4 2.8 6.8 3.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 EGG06510.1 - 2.7 7.5 8.2 4.7 6.7 5.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.5 EGG06510.1 - 3.9 6.4 9.2 6 5.8 6.4 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 EGG06510.1 - 7.3 4.4 7.0 11 3.9 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EGG06510.1 - 9.5 5.3 12.7 22 4.1 8.8 1.6 1 0 0 1 1 1 0 NOA36 protein Velvet PF11754.3 EGG06512.1 - 5.4e-15 55.5 0.0 5.7e-13 48.9 0.0 2.0 1 1 1 2 2 2 2 Velvet factor Mito_carr PF00153.22 EGG06515.1 - 4.3e-68 225.0 4.0 1.5e-22 79.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA_int_endo PF01974.12 EGG06516.1 - 3.5e-14 52.3 0.0 6.3e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EGG06516.1 - 0.00086 18.8 0.0 0.0062 16.0 0.0 2.2 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Lipase_3 PF01764.20 EGG06517.1 - 4.2e-12 45.8 0.0 2.6e-11 43.3 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EGG06517.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG06517.1 - 0.024 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold COMPASS-Shg1 PF05205.7 EGG06517.1 - 0.047 13.9 1.1 0.41 10.9 0.1 2.5 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Abhydrolase_5 PF12695.2 EGG06517.1 - 0.055 13.2 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family WW PF00397.21 EGG06518.1 - 0.84 9.5 6.0 0.23 11.3 0.7 2.5 2 0 0 2 2 2 0 WW domain WW PF00397.21 EGG06519.1 - 0.0033 17.2 1.5 0.0033 17.2 1.0 2.3 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.4 EGG06519.1 - 0.011 15.7 16.2 0.011 15.7 11.2 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Innate_immun PF12782.2 EGG06520.1 - 1.1 8.4 9.6 1.2 8.2 6.6 1.0 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family PUF PF00806.14 EGG06523.1 - 0.13 11.8 0.3 0.92 9.1 0.0 2.5 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat SprA-related PF12118.3 EGG06525.1 - 0.38 10.0 20.9 0.45 9.7 14.5 1.0 1 0 0 1 1 1 0 SprA-related family Herpes_LMP1 PF05297.6 EGG06525.1 - 0.58 9.0 6.0 0.61 8.9 4.2 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3827 PF12877.2 EGG06525.1 - 3.6 5.5 19.0 3.9 5.4 13.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SAPS PF04499.10 EGG06525.1 - 7 5.1 11.6 7.6 5.0 8.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Spore_coat_CotO PF14153.1 EGG06525.1 - 8.3 5.8 12.8 9.8 5.5 8.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO p450 PF00067.17 EGG06527.1 - 4.6e-59 200.1 0.0 6.1e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EGG06528.1 - 5.1e-66 222.4 0.3 1.3e-65 221.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG06528.1 - 3.4e-31 108.2 0.1 3.3e-30 105.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.21 EGG06528.1 - 1.4e-10 41.0 1.8 2.8e-10 40.1 0.2 2.3 2 0 0 2 2 2 1 FHA domain APH PF01636.18 EGG06528.1 - 0.029 14.1 0.0 0.69 9.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EGG06528.1 - 0.03 13.3 0.0 0.073 12.0 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Zip PF02535.17 EGG06530.1 - 8.4 5.2 6.2 8.6 5.2 4.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DSPc PF00782.15 EGG06531.1 - 9.6e-36 122.3 0.0 4e-26 91.1 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGG06531.1 - 1.5e-06 27.7 0.0 0.0034 16.7 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Myotub-related PF06602.9 EGG06531.1 - 0.0026 16.5 0.1 0.56 8.9 0.0 2.2 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.1 EGG06531.1 - 0.055 13.5 0.2 8.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate Lon_C PF05362.8 EGG06532.1 - 6.8e-62 208.4 0.0 1.6e-61 207.1 0.0 1.7 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EGG06532.1 - 1.1e-28 100.2 0.4 1.1e-28 100.2 0.3 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EGG06532.1 - 2.1e-23 82.9 0.0 1.2e-22 80.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGG06532.1 - 1.2e-07 31.5 0.0 2.9e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 EGG06532.1 - 7.1e-06 24.9 0.0 1.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain ChlI PF13541.1 EGG06532.1 - 9.9e-06 25.0 0.1 2.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EGG06532.1 - 2.8e-05 24.1 2.1 0.00076 19.5 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EGG06532.1 - 3.3e-05 23.8 0.0 9.8e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EGG06532.1 - 0.00014 22.6 0.0 0.00079 20.2 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGG06532.1 - 0.00016 21.8 0.1 0.0049 17.0 0.0 3.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGG06532.1 - 0.00029 19.9 0.0 0.0017 17.4 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGG06532.1 - 0.00041 20.2 0.0 0.001 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG06532.1 - 0.0071 16.6 0.7 0.025 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGG06532.1 - 0.025 14.7 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SKI PF01202.17 EGG06532.1 - 0.026 14.4 0.2 0.095 12.5 0.0 2.1 2 0 0 2 2 1 0 Shikimate kinase AAA_25 PF13481.1 EGG06532.1 - 0.036 13.4 0.0 0.086 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EGG06532.1 - 0.04 13.8 2.3 1.5 8.6 0.0 3.5 2 1 1 3 3 3 0 AAA domain DUF258 PF03193.11 EGG06532.1 - 0.044 12.9 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EGG06532.1 - 0.048 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 EGG06532.1 - 0.048 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EGG06532.1 - 0.059 13.6 3.1 0.33 11.2 0.0 3.4 4 0 0 4 4 3 0 ABC transporter RXT2_N PF08595.6 EGG06532.1 - 3.6 7.3 17.2 0.039 13.7 0.4 4.5 4 1 1 5 5 5 0 RXT2-like, N-terminal DSPn PF14671.1 EGG06533.1 - 8.3e-37 126.3 0.0 2.7e-35 121.3 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EGG06533.1 - 2e-16 59.8 0.0 5.6e-16 58.3 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGG06533.1 - 3.3e-05 23.3 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGG06533.1 - 0.00063 19.8 0.0 0.00084 19.4 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EGG06533.1 - 0.006 16.8 0.1 0.013 15.7 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family VIT1 PF01988.14 EGG06534.1 - 0.33 10.4 0.0 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 VIT family Ribosomal_S13 PF00416.17 EGG06535.1 - 0.094 13.1 0.9 0.16 12.4 0.7 1.5 1 0 0 1 1 1 0 Ribosomal protein S13/S18 DUF2812 PF11193.3 EGG06535.1 - 0.22 11.6 1.4 0.36 10.9 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2812) Med16 PF11635.3 EGG06535.1 - 2.2 6.1 5.2 7.9 4.2 3.6 1.9 1 1 0 1 1 1 0 Mediator complex subunit 16 Pkinase PF00069.20 EGG06536.1 - 1.4e-63 214.4 0.0 1.7e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG06536.1 - 4.2e-34 117.7 0.0 5.6e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG06536.1 - 4.4e-09 35.7 0.0 7e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGG06536.1 - 0.0024 16.9 0.1 0.0053 15.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGG06536.1 - 0.0044 16.7 0.3 0.0086 15.8 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EGG06536.1 - 0.021 13.6 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase WD40 PF00400.27 EGG06539.1 - 3e-47 156.8 10.5 1.1e-09 37.7 0.2 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGG06539.1 - 1e-06 27.8 0.2 0.00022 20.1 0.0 3.0 1 1 2 4 4 4 2 Nup133 N terminal like DUF3312 PF11768.3 EGG06539.1 - 1.4e-06 26.8 0.0 2.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Nup160 PF11715.3 EGG06539.1 - 0.0058 14.8 0.5 1.4 6.9 0.1 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EGG06539.1 - 0.069 12.8 0.0 7.7 6.1 0.0 3.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A AMP-binding PF00501.23 EGG06540.1 - 4.4e-77 259.2 0.0 5.8e-77 258.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DnaJ PF00226.26 EGG06543.1 - 1.3e-09 37.5 0.0 6.5e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.1 EGG06543.1 - 0.00015 22.0 0.3 0.77 10.1 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGG06543.1 - 0.0022 17.5 0.1 0.012 15.2 0.0 2.3 2 1 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 EGG06543.1 - 0.0022 17.8 1.8 0.12 12.2 0.1 3.8 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGG06543.1 - 0.021 15.3 0.2 1.5e+02 3.4 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGG06543.1 - 0.09 13.2 6.6 1.7 9.2 0.1 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGG06543.1 - 0.13 12.1 1.3 21 5.2 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Sad1_UNC PF07738.8 EGG06545.1 - 2.3e-30 105.1 0.0 3.3e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Alpha_kinase PF02816.13 EGG06546.1 - 8.1e-12 45.1 0.0 9.5e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family DUF2357 PF09823.4 EGG06548.1 - 0.039 13.0 2.1 0.094 11.7 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) Cytochrom_C PF00034.16 EGG06549.1 - 3.8e-09 37.2 0.5 7.1e-09 36.3 0.3 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EGG06549.1 - 7.5e-07 29.2 4.7 1.1e-05 25.5 3.3 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EGG06549.1 - 0.015 14.7 1.5 0.023 14.1 0.3 1.9 1 1 0 2 2 2 0 Cytochrome c-550 domain UPF0128 PF03673.8 EGG06549.1 - 0.045 13.0 0.1 0.051 12.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) IPPT PF01715.12 EGG06550.1 - 6.8e-58 195.6 0.0 9.1e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 IPP transferase AAA_18 PF13238.1 EGG06550.1 - 0.00028 21.1 0.1 0.038 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGG06550.1 - 0.012 15.7 0.1 0.66 10.1 0.0 3.1 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EGG06550.1 - 0.012 14.6 0.9 0.023 13.6 0.0 1.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EGG06550.1 - 0.024 15.4 0.1 0.046 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGG06550.1 - 0.035 14.4 1.2 0.12 12.7 0.1 2.2 2 1 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 EGG06550.1 - 0.07 12.9 0.5 0.7 9.7 0.3 2.6 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGG06550.1 - 0.1 12.2 0.1 1.1 8.8 0.0 2.3 2 1 0 2 2 2 0 Archaeal ATPase KilA-N PF04383.8 EGG06552.1 - 0.0036 16.9 0.0 0.0036 16.9 0.0 1.1 1 0 0 1 1 1 1 KilA-N domain HTH_26 PF13443.1 EGG06552.1 - 0.059 13.5 0.2 0.069 13.3 0.1 1.1 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Longin PF13774.1 EGG06553.1 - 6.5e-17 60.8 0.0 1.4e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EGG06553.1 - 1.5e-14 53.3 0.7 2.7e-14 52.5 0.5 1.4 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 EGG06553.1 - 0.11 12.2 0.2 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 zf-met2 PF12907.2 EGG06557.1 - 3.7e-18 65.2 3.0 3.7e-18 65.2 2.1 1.4 2 0 0 2 2 2 1 Zinc-binding 4F5 PF04419.9 EGG06557.1 - 7.3e-08 33.0 12.5 5e-07 30.3 6.2 2.1 2 0 0 2 2 2 2 4F5 protein family MFS_1 PF07690.11 EGG06559.1 - 3.3e-42 144.4 47.5 2.3e-40 138.4 32.0 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG06559.1 - 1.1e-08 34.1 5.7 1.1e-08 34.1 4.0 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EGG06559.1 - 1e-07 30.5 25.9 3.8e-07 28.6 18.0 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.11 EGG06559.1 - 0.15 11.5 7.8 0.026 14.0 2.3 2.0 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 PseudoU_synth_2 PF00849.17 EGG06560.1 - 6.3e-18 65.1 0.1 1.6e-15 57.3 0.0 2.3 1 1 0 1 1 1 1 RNA pseudouridylate synthase GFA PF04828.9 EGG06560.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DUF2863 PF11062.3 EGG06560.1 - 0.12 10.4 0.1 0.16 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) BTV_NS2 PF04514.7 EGG06561.1 - 0.32 9.8 5.5 0.36 9.6 3.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Pox_Ag35 PF03286.9 EGG06561.1 - 1.4 8.4 5.4 2 7.8 3.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HSP70 PF00012.15 EGG06561.1 - 2.4 5.9 7.2 2.6 5.8 5.0 1.0 1 0 0 1 1 1 0 Hsp70 protein RNA_pol_3_Rpc31 PF11705.3 EGG06563.1 - 0.014 15.3 2.4 0.019 14.9 1.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 WTX PF09422.5 EGG06563.1 - 0.036 13.0 0.3 0.038 12.9 0.2 1.1 1 0 0 1 1 1 0 WTX protein Phosducin PF02114.11 EGG06563.1 - 0.078 11.6 0.0 0.53 8.9 0.0 1.9 2 0 0 2 2 2 0 Phosducin DegS PF05384.6 EGG06564.1 - 6.2 6.0 12.1 0.67 9.1 3.4 2.6 1 1 1 2 2 2 0 Sensor protein DegS POP1 PF06978.6 EGG06565.1 - 0.00076 19.1 3.9 0.45 10.1 0.6 2.5 2 1 0 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 E1-E2_ATPase PF00122.15 EGG06567.1 - 1.9e-63 213.6 0.8 5.1e-63 212.1 0.6 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGG06567.1 - 7.9e-31 108.1 0.0 9.9e-30 104.5 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EGG06567.1 - 7e-23 81.0 9.5 1.1e-19 70.6 3.0 3.5 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EGG06567.1 - 2.8e-19 68.8 0.0 5.9e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGG06567.1 - 3.5e-16 59.9 0.0 6.6e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGG06567.1 - 2.5e-13 49.2 0.0 6.7e-13 47.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGG06567.1 - 1e-05 25.2 0.8 0.017 14.7 0.4 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase EST1_DNA_bind PF10373.4 EGG06567.1 - 0.16 11.1 0.0 10 5.2 0.0 2.4 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain DUF4064 PF13273.1 EGG06567.1 - 0.19 11.8 3.9 2.9 8.0 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) OPA3 PF07047.7 EGG06569.1 - 2.9e-22 78.8 0.1 3.5e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) MutS_V PF00488.16 EGG06571.1 - 4.5e-39 134.2 0.2 4e-20 72.2 0.3 3.2 1 1 1 2 2 2 2 MutS domain V MutS_III PF05192.13 EGG06571.1 - 7.1e-14 52.0 0.2 1.1e-13 51.3 0.2 1.3 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EGG06571.1 - 0.0058 16.7 0.0 0.021 14.9 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV DUF4559 PF15112.1 EGG06571.1 - 0.49 9.4 1.0 0.78 8.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Rer1 PF03248.8 EGG06572.1 - 7.5e-76 253.6 1.3 8.7e-76 253.4 0.9 1.0 1 0 0 1 1 1 1 Rer1 family DUF4395 PF14340.1 EGG06572.1 - 0.014 15.4 1.6 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) 2TM PF13239.1 EGG06572.1 - 0.11 12.5 2.2 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 2TM domain PAH PF02671.16 EGG06573.1 - 2.4e-39 132.6 2.5 4.7e-14 51.7 0.1 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EGG06573.1 - 5.7e-22 77.3 0.0 4.7e-21 74.4 0.0 2.6 3 0 0 3 3 3 1 Sin3 family co-repressor Foie-gras_1 PF11817.3 EGG06574.1 - 1.7e-40 139.0 0.6 3.8e-40 137.9 0.1 1.7 2 0 0 2 2 2 1 Foie gras liver health family 1 SNAP PF14938.1 EGG06574.1 - 0.00029 20.0 0.5 0.00078 18.6 0.3 1.7 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TRAPPC10 PF12584.3 EGG06574.1 - 0.0061 16.0 0.9 0.018 14.5 0.0 2.2 3 0 0 3 3 3 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.2 EGG06574.1 - 0.012 15.4 0.2 0.03 14.1 0.2 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking TPR_11 PF13414.1 EGG06575.1 - 6.6e-15 54.5 2.9 1.7e-11 43.6 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGG06575.1 - 2.7e-10 39.3 12.5 1.4e-05 24.4 1.1 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGG06575.1 - 2.5e-07 30.0 11.8 0.013 15.3 0.4 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGG06575.1 - 0.00026 20.8 3.0 0.0089 15.9 0.8 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGG06575.1 - 0.0012 19.4 3.9 0.52 11.0 0.3 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EGG06575.1 - 0.0068 16.5 0.9 0.04 14.0 0.4 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EGG06575.1 - 0.053 13.3 7.3 5.1 7.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGG06575.1 - 0.075 13.7 3.1 1.5 9.6 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGG06575.1 - 1.2 9.1 5.0 21 5.2 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGG06575.1 - 1.2 9.7 5.2 39 5.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CCHC_3 PF13917.1 EGG06578.1 - 0.39 10.4 5.0 0.2 11.4 1.7 1.9 2 0 0 2 2 2 0 Zinc knuckle Lipocalin_3 PF12702.2 EGG06579.1 - 0.049 13.6 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipocalin-like AIP3 PF03915.8 EGG06585.1 - 0.035 13.0 0.3 0.06 12.2 0.2 1.4 1 1 0 1 1 1 0 Actin interacting protein 3 zf-ZPR1 PF03367.8 EGG06585.1 - 0.044 12.9 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 ZPR1 zinc-finger domain WEMBL PF05701.6 EGG06585.1 - 0.053 11.9 0.0 0.064 11.7 0.0 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light OTU PF02338.14 EGG06590.1 - 6.9e-09 36.3 0.0 1.7e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGG06590.1 - 0.00024 20.5 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain SNARE PF05739.14 EGG06592.1 - 1.1e-15 57.0 1.1 1.1e-15 57.0 0.7 2.8 3 0 0 3 3 2 1 SNARE domain Syntaxin PF00804.20 EGG06592.1 - 1.1e-14 54.3 3.0 1.1e-14 54.3 2.1 3.0 3 1 0 3 3 2 1 Syntaxin zf-C4H2 PF10146.4 EGG06592.1 - 3.3e-05 24.0 1.4 0.2 11.6 0.0 2.4 3 0 0 3 3 3 2 Zinc finger-containing protein Syntaxin-18_N PF10496.4 EGG06592.1 - 0.0095 15.7 1.8 0.11 12.3 0.0 3.2 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus Peripla_BP_2 PF01497.13 EGG06592.1 - 0.049 12.7 0.2 4.5 6.3 0.1 2.3 2 0 0 2 2 2 0 Periplasmic binding protein Sed5p PF11416.3 EGG06592.1 - 0.066 12.6 0.1 0.066 12.6 0.1 2.2 2 0 0 2 2 2 0 Integral membrane protein Sed5p Cluap1 PF10234.4 EGG06592.1 - 0.17 11.0 8.6 0.68 9.0 1.0 2.5 2 1 1 3 3 3 0 Clusterin-associated protein-1 FlxA PF14282.1 EGG06592.1 - 0.38 10.7 22.3 0.028 14.3 4.4 2.6 2 0 0 2 2 2 0 FlxA-like protein BLOC1_2 PF10046.4 EGG06592.1 - 0.42 10.7 6.9 4.2 7.5 0.1 3.3 2 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.3 EGG06592.1 - 1.1 8.4 11.9 0.65 9.2 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.6 EGG06592.1 - 1.5 9.3 7.5 7.8 6.9 0.3 2.9 3 0 0 3 3 2 0 Syntaxin 6, N-terminal FliJ PF02050.11 EGG06592.1 - 1.8 8.6 15.0 0.036 14.1 2.1 2.8 2 1 0 2 2 2 0 Flagellar FliJ protein HAUS-augmin3 PF14932.1 EGG06592.1 - 2.4 7.2 10.9 0.47 9.6 2.5 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.7 EGG06592.1 - 4.1 7.2 8.4 5.2 6.8 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF16 PF01519.11 EGG06592.1 - 4.1 7.6 10.1 0.83 9.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 ALIX_LYPXL_bnd PF13949.1 EGG06592.1 - 4.6 6.1 13.7 0.086 11.7 0.2 2.9 2 1 1 3 3 3 0 ALIX V-shaped domain binding to HIV SlyX PF04102.7 EGG06592.1 - 6.6 7.1 11.2 1.9 8.9 0.7 2.9 3 0 0 3 3 2 0 SlyX FlaC_arch PF05377.6 EGG06592.1 - 9.2 6.2 8.2 3.8 7.4 0.0 3.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4355 PF14265.1 EGG06594.1 - 0.038 13.9 23.5 0.044 13.7 16.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Mucin PF01456.12 EGG06594.1 - 0.21 11.3 3.4 0.25 11.1 2.3 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein TFIIF_alpha PF05793.7 EGG06594.1 - 0.42 8.9 32.1 0.47 8.7 22.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2890 PF11081.3 EGG06594.1 - 0.42 10.6 20.8 0.68 9.9 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) YjgP_YjgQ PF03739.9 EGG06594.1 - 0.75 8.4 4.5 0.92 8.1 3.1 1.0 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF572 PF04502.8 EGG06594.1 - 0.77 8.9 19.3 0.91 8.6 13.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDC45 PF02724.9 EGG06594.1 - 1 7.3 21.4 1.1 7.1 14.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.8 EGG06594.1 - 1.1 7.3 24.8 1.3 7.1 17.2 1.0 1 0 0 1 1 1 0 Utp14 protein RRN3 PF05327.6 EGG06594.1 - 1.1 7.2 15.5 1.2 7.1 10.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3987 PF13148.1 EGG06594.1 - 1.1 7.7 10.7 1.2 7.6 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) MIP-T3 PF10243.4 EGG06594.1 - 1.5 7.2 24.6 1.8 6.9 17.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Rtf2 PF04641.7 EGG06594.1 - 1.6 7.8 15.7 1.8 7.6 10.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger LTV PF04180.9 EGG06594.1 - 1.8 7.9 20.8 2.4 7.5 14.4 1.2 1 0 0 1 1 1 0 Low temperature viability protein FAM60A PF15396.1 EGG06594.1 - 1.9 8.2 9.6 2.2 7.9 6.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CENP-T PF15511.1 EGG06594.1 - 1.9 7.6 18.2 2 7.5 12.6 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EGG06594.1 - 2.5 5.9 31.1 2.9 5.7 21.6 1.0 1 0 0 1 1 1 0 Nop14-like family DUF3513 PF12026.3 EGG06594.1 - 2.9 7.3 7.8 3.3 7.2 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) DDRGK PF09756.4 EGG06594.1 - 3.4 7.0 25.4 5.1 6.4 17.6 1.2 1 0 0 1 1 1 0 DDRGK domain NARP1 PF12569.3 EGG06594.1 - 3.5 6.2 12.1 3.7 6.1 8.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PRP21_like_P PF12230.3 EGG06594.1 - 3.7 7.0 19.7 6.2 6.2 13.6 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Daxx PF03344.10 EGG06594.1 - 4.1 5.7 29.8 4.7 5.5 20.7 1.0 1 0 0 1 1 1 0 Daxx Family Vfa1 PF08432.5 EGG06594.1 - 4.5 7.2 23.0 5.6 6.9 15.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 eIF3_subunit PF08597.5 EGG06594.1 - 4.8 6.6 22.6 6.6 6.2 15.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Merozoite_SPAM PF07133.6 EGG06594.1 - 8.1 6.3 41.2 11 5.9 28.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2413 PF10310.4 EGG06594.1 - 9.1 4.9 20.8 10 4.8 14.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) zf-CCCH PF00642.19 EGG06595.1 - 2.1e-10 39.9 9.4 8.8e-07 28.4 1.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGG06595.1 - 0.0014 18.5 14.4 0.018 15.0 2.0 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type Mem_trans PF03547.13 EGG06597.1 - 1.3e-34 119.1 0.0 1.3e-34 119.1 0.0 2.0 2 1 0 2 2 2 1 Membrane transport protein TORC_M PF12885.2 EGG06597.1 - 0.033 13.9 0.6 0.069 12.9 0.4 1.4 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Clat_adaptor_s PF01217.15 EGG06598.1 - 1.2e-39 135.3 0.1 1.3e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_M41 PF01434.13 EGG06599.1 - 2.2e-70 236.4 0.1 3.2e-70 235.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGG06599.1 - 1e-41 142.2 0.0 3e-41 140.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EGG06599.1 - 6e-09 36.0 0.2 6e-09 36.0 0.2 2.3 2 0 0 2 2 2 1 FtsH Extracellular AAA_17 PF13207.1 EGG06599.1 - 0.0011 19.7 0.0 0.0032 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGG06599.1 - 0.0015 18.6 0.0 0.2 11.8 0.1 2.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EGG06599.1 - 0.0021 16.8 0.0 0.0045 15.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EGG06599.1 - 0.0022 17.0 0.2 0.014 14.4 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGG06599.1 - 0.0076 15.9 1.7 0.016 14.9 0.5 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EGG06599.1 - 0.019 14.6 0.1 0.071 12.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EGG06599.1 - 0.02 13.9 0.0 0.049 12.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EGG06599.1 - 0.027 14.4 0.1 0.18 11.7 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.12 EGG06599.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EGG06599.1 - 0.09 12.1 1.2 0.22 10.9 0.4 1.8 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EGG06599.1 - 0.13 12.1 0.1 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGG06599.1 - 0.22 11.4 1.0 0.76 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Formyl_trans_N PF00551.14 EGG06601.1 - 5e-38 130.4 0.0 5.8e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase DUF1743 PF08489.6 EGG06601.1 - 0.071 12.8 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) SNARE PF05739.14 EGG06603.1 - 5.3e-08 32.4 2.5 5.3e-08 32.4 1.7 3.3 3 0 0 3 3 3 1 SNARE domain V-SNARE_C PF12352.3 EGG06603.1 - 0.049 13.6 4.0 0.13 12.3 0.3 2.7 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EGG06603.1 - 0.4 10.3 2.9 2.3 7.9 0.2 2.4 2 0 0 2 2 2 0 Sec20 FliD_C PF07195.7 EGG06603.1 - 0.76 9.0 10.6 3.1 7.0 7.4 2.2 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF1754 PF08555.5 EGG06606.1 - 0.059 13.9 0.1 0.12 13.0 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Mem_trans PF03547.13 EGG06607.1 - 4.2e-31 107.6 0.3 4.2e-31 107.6 0.2 2.1 2 1 0 2 2 2 1 Membrane transport protein Dec-1 PF04624.9 EGG06607.1 - 4.2 7.0 7.7 0.3 10.7 0.3 2.3 2 0 0 2 2 2 0 Dec-1 repeat DUF2935 PF11155.3 EGG06608.1 - 0.043 13.9 0.1 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Pox_Ag35 PF03286.9 EGG06609.1 - 0.0022 17.5 0.8 0.0022 17.5 0.6 2.0 2 0 0 2 2 2 1 Pox virus Ag35 surface protein Parvo_coat PF00740.13 EGG06609.1 - 0.074 12.0 7.1 0.075 11.9 4.9 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF1754 PF08555.5 EGG06609.1 - 0.37 11.4 13.7 0.19 12.3 2.0 2.2 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Senescence_reg PF04520.8 EGG06609.1 - 0.44 11.0 6.8 0.63 10.5 4.7 1.2 1 0 0 1 1 1 0 Senescence regulator NAM-associated PF14303.1 EGG06609.1 - 1.9 8.7 17.8 2.9 8.1 12.4 1.3 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain PBP1_TM PF14812.1 EGG06609.1 - 6.7 7.1 14.2 0.54 10.5 5.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Herpes_UL14 PF03580.9 EGG06609.1 - 7.1 6.4 7.4 0.88 9.3 1.3 1.9 2 0 0 2 2 2 0 Herpesvirus UL14-like protein zf-C2H2_4 PF13894.1 EGG06611.1 - 0.0012 19.0 2.1 0.0012 19.0 1.5 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger DUF3614 PF12267.3 EGG06611.1 - 0.33 11.2 4.2 0.98 9.6 2.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Mem_trans PF03547.13 EGG06612.1 - 4.3e-33 114.1 7.5 4.3e-33 114.1 5.2 1.6 2 1 0 2 2 2 1 Membrane transport protein Memo PF01875.12 EGG06613.1 - 1.7e-79 266.5 0.0 2.1e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein FMN_dh PF01070.13 EGG06614.1 - 0.026 13.3 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF605 PF04652.11 EGG06615.1 - 1.3 8.3 22.7 1.6 8.0 15.7 1.3 1 0 0 1 1 1 0 Vta1 like HTH_45 PF14947.1 EGG06617.1 - 0.0091 15.7 0.7 9.9 6.0 0.0 3.2 3 0 0 3 3 3 2 Winged helix-turn-helix Pep3_Vps18 PF05131.9 EGG06619.1 - 4.1e-33 113.9 0.1 9.7e-33 112.6 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EGG06619.1 - 4.4e-13 49.0 7.3 2.2e-09 37.0 0.1 3.4 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.4 EGG06619.1 - 1.4e-06 28.4 0.6 1.4e-06 28.4 0.5 2.7 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.1 EGG06619.1 - 0.00022 20.9 3.9 0.00022 20.9 2.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGG06619.1 - 0.00074 19.3 0.3 1.1 9.1 0.5 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EGG06619.1 - 0.0033 17.2 3.0 0.0033 17.2 2.1 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGG06619.1 - 0.023 14.7 1.9 0.023 14.7 1.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGG06619.1 - 0.044 13.9 0.5 0.35 11.0 0.7 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger DNA_pol3_theta PF06440.6 EGG06619.1 - 0.064 12.8 0.1 4.8 6.8 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase III, theta subunit zf-C3HC4 PF00097.20 EGG06619.1 - 0.066 12.8 3.3 0.19 11.4 2.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.4 EGG06619.1 - 0.37 10.8 5.1 0.39 10.8 1.0 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_3 PF13920.1 EGG06619.1 - 6.7 6.4 6.8 1.1 8.9 1.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PAT1 PF09770.4 EGG06620.1 - 5 5.2 41.8 8.9 4.4 29.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EGG06620.1 - 9.2 6.0 12.8 16 5.2 8.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Usp PF00582.21 EGG06622.1 - 1.4e-20 73.9 0.4 2.3e-20 73.2 0.0 1.5 2 0 0 2 2 2 1 Universal stress protein family Mnd1 PF03962.10 EGG06623.1 - 1.4e-47 161.8 5.2 1.5e-47 161.6 3.6 1.0 1 0 0 1 1 1 1 Mnd1 family AAA_13 PF13166.1 EGG06623.1 - 3.8e-05 22.3 5.5 4.6e-05 22.1 3.8 1.0 1 0 0 1 1 1 1 AAA domain IncA PF04156.9 EGG06623.1 - 0.00093 18.8 10.3 0.0012 18.5 7.2 1.1 1 0 0 1 1 1 1 IncA protein Methyltransf_7 PF03492.10 EGG06623.1 - 0.0047 15.7 0.7 0.0051 15.6 0.5 1.2 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase TrmB PF01978.14 EGG06623.1 - 0.079 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF848 PF05852.6 EGG06623.1 - 1.1 9.1 9.2 0.23 11.2 1.5 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DivIC PF04977.10 EGG06623.1 - 1.2 8.6 10.5 0.9 9.0 0.4 2.3 1 1 1 2 2 2 0 Septum formation initiator Prefoldin_2 PF01920.15 EGG06623.1 - 3 7.6 12.6 1.8 8.3 7.4 1.6 2 0 0 2 2 2 0 Prefoldin subunit OPT PF03169.10 EGG06624.1 - 1.1e-90 304.8 44.4 1.3e-89 301.3 30.7 1.9 1 1 0 1 1 1 1 OPT oligopeptide transporter protein MgtE PF01769.11 EGG06624.1 - 0.006 16.8 0.0 0.006 16.8 0.0 4.6 5 0 0 5 5 5 1 Divalent cation transporter PfkB PF00294.19 EGG06625.1 - 5.9e-37 127.4 0.0 8.3e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ala_racemase_N PF01168.15 EGG06625.1 - 0.014 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain Nitro_FeMo-Co PF02579.12 EGG06625.1 - 0.022 14.8 0.1 0.9 9.6 0.0 2.4 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor MRP-L28 PF09812.4 EGG06626.1 - 3.7e-07 30.1 8.6 1.4e-06 28.2 4.7 2.0 1 1 1 2 2 2 1 Mitochondrial ribosomal protein L28 SpoIIIAH PF12685.2 EGG06626.1 - 0.087 12.3 2.0 0.11 11.9 1.4 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF1283 PF06932.6 EGG06626.1 - 0.092 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) Raptor_N PF14538.1 EGG06627.1 - 1.6e-52 177.4 0.0 3.8e-52 176.2 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 EGG06627.1 - 5.4e-05 22.9 0.2 0.017 15.1 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat WD40 PF00400.27 EGG06627.1 - 9.6e-05 22.1 3.5 3.8 7.5 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGG06627.1 - 0.021 14.5 0.4 2 8.1 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.1 EGG06627.1 - 0.053 13.7 0.0 2.2 8.6 0.0 3.1 1 1 0 1 1 1 0 HEAT repeats Pox_MCEL PF03291.11 EGG06629.1 - 1.7e-77 260.5 0.0 1.9e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 EGG06629.1 - 1.1e-09 38.1 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG06629.1 - 4e-09 36.2 0.0 5.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG06629.1 - 4.7e-09 36.6 0.0 7.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG06629.1 - 7.2e-09 36.0 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG06629.1 - 4e-08 33.8 0.0 6.2e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG06629.1 - 2.6e-07 30.9 0.1 3.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG06629.1 - 4e-05 23.6 0.0 6.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EGG06629.1 - 0.00013 21.0 0.0 0.00019 20.4 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.9 EGG06629.1 - 0.0098 15.2 0.0 0.022 14.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EGG06629.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase WD40 PF00400.27 EGG06630.1 - 1.2e-11 43.9 15.8 0.00051 19.8 0.1 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat RWD PF05773.17 EGG06630.1 - 0.0017 18.2 0.0 0.005 16.7 0.0 1.8 1 0 0 1 1 1 1 RWD domain zf-rbx1 PF12678.2 EGG06630.1 - 0.39 10.8 13.2 0.99 9.5 9.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger Peptidase_C50 PF03568.12 EGG06631.1 - 3.4e-93 312.3 0.0 4e-93 312.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.2 EGG06631.1 - 7.6e-09 35.0 0.0 0.0019 17.3 0.0 2.3 1 1 0 2 2 2 2 CHAT domain Epimerase PF01370.16 EGG06633.1 - 8.1e-16 58.1 0.0 1.6e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGG06633.1 - 2.9e-14 52.4 0.0 8.1e-14 50.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGG06633.1 - 4e-11 42.3 0.0 1.3e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGG06633.1 - 2.9e-07 30.6 0.4 1.4e-06 28.4 0.3 2.1 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGG06633.1 - 0.0001 22.2 0.4 0.0003 20.7 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGG06633.1 - 0.0088 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGG06633.1 - 0.069 12.0 0.0 0.35 9.6 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain KR PF08659.5 EGG06633.1 - 0.11 12.1 0.5 0.64 9.6 0.4 2.0 1 1 0 1 1 1 0 KR domain Epimerase PF01370.16 EGG06634.1 - 9.9e-15 54.6 0.0 1.7e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGG06634.1 - 2.1e-12 46.3 0.0 5.3e-12 45.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGG06634.1 - 2.9e-11 42.7 0.0 1.1e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGG06634.1 - 5.9e-07 29.6 0.7 6.9e-06 26.1 0.4 2.4 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EGG06634.1 - 0.0036 17.2 1.6 0.031 14.1 0.4 2.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGG06634.1 - 0.0077 15.9 2.0 0.014 15.0 0.2 2.3 2 1 0 2 2 2 1 KR domain Ldh_1_N PF00056.18 EGG06634.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EGG06635.1 - 3.1e-12 45.8 0.0 7.3e-12 44.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGG06635.1 - 2.9e-11 43.2 0.1 1.2e-10 41.2 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGG06635.1 - 1.3e-07 31.7 0.2 1.9e-06 28.0 0.1 2.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGG06635.1 - 3.5e-06 26.1 0.1 2.7e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EGG06635.1 - 0.043 12.7 0.1 0.38 9.6 0.0 2.3 2 1 0 2 2 2 0 RmlD substrate binding domain DUF605 PF04652.11 EGG06636.1 - 0.037 13.4 5.3 0.053 12.9 3.6 1.2 1 0 0 1 1 1 0 Vta1 like PEX11 PF05648.9 EGG06637.1 - 2e-61 207.1 4.3 2.2e-61 206.9 3.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ORC4_C PF14629.1 EGG06638.1 - 1.1e-22 80.4 0.3 3.2e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EGG06638.1 - 3.3e-09 36.9 0.1 1.6e-08 34.7 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 EGG06638.1 - 0.00029 21.0 0.1 0.0022 18.1 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGG06638.1 - 0.00097 19.2 0.3 0.017 15.2 0.2 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGG06638.1 - 0.002 17.1 0.2 0.018 13.9 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EGG06638.1 - 0.082 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RNase_H PF00075.19 EGG06641.1 - 9.7e-06 25.9 0.0 2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EGG06641.1 - 3e-05 23.6 0.0 0.00012 21.8 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase-like zf-RNPHF PF08080.7 EGG06642.1 - 0.09 12.2 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 RNPHF zinc finger Alpha_kinase PF02816.13 EGG06643.1 - 1.7e-07 31.0 0.0 2.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family RhoGAP PF00620.22 EGG06644.1 - 2.8e-28 98.4 0.0 7e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain Ribonuclease_3 PF00636.21 EGG06646.1 - 9.6e-08 32.4 0.1 0.00084 19.7 0.0 3.0 2 2 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGG06646.1 - 0.00073 19.4 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like UQ_con PF00179.21 EGG06647.1 - 2.2e-46 156.7 0.1 2.7e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGG06647.1 - 0.025 14.4 0.3 0.044 13.6 0.2 1.7 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 EGG06647.1 - 0.064 13.0 0.0 0.2 11.3 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B Sec34 PF04136.10 EGG06649.1 - 4.8e-26 91.3 5.5 1.6e-25 89.6 3.8 1.9 1 0 0 1 1 1 1 Sec34-like family DUF1828 PF08861.5 EGG06652.1 - 0.033 13.8 0.8 0.053 13.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF1828 DUF4407 PF14362.1 EGG06652.1 - 3.9 6.3 10.9 5 5.9 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AFOR_C PF01314.13 EGG06654.1 - 0.15 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 Med9 PF07544.8 EGG06655.1 - 0.024 14.3 0.7 0.067 12.9 0.5 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Phage_Gp19 PF09355.5 EGG06656.1 - 0.05 13.4 0.3 2.9 7.7 0.1 2.8 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 Tox-SHH PF15652.1 EGG06656.1 - 0.078 13.5 0.2 0.3 11.6 0.1 2.0 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature Alpha-amyl_C2 PF07821.7 EGG06657.1 - 0.025 14.4 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain Adap_comp_sub PF00928.16 EGG06659.1 - 2.3e-88 295.6 0.0 3e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGG06659.1 - 2.1e-09 37.2 0.9 3.7e-09 36.4 0.6 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_S8 PF00410.14 EGG06661.1 - 1e-13 51.2 0.0 1.3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 DUF2269 PF10027.4 EGG06663.1 - 0.019 14.7 4.1 0.029 14.1 2.9 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) TRIQK PF15168.1 EGG06663.1 - 0.091 12.6 1.3 4.4 7.3 0.0 3.0 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family Cyclin_N PF00134.18 EGG06664.1 - 3e-45 152.8 0.8 9.4e-44 148.0 0.4 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGG06664.1 - 6.5e-27 93.8 0.0 4.1e-26 91.2 0.0 2.3 1 1 0 1 1 1 1 Cyclin, C-terminal domain TMA7 PF09072.5 EGG06664.1 - 2.7 8.5 6.0 4.2 7.8 4.2 1.3 1 0 0 1 1 1 0 Translation machinery associated TMA7 WD40 PF00400.27 EGG06666.1 - 1.4e-23 81.8 9.0 1.9e-09 37.0 0.2 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGG06666.1 - 7.9e-17 60.9 0.0 5.8e-16 58.1 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex TFIIE-A_C-term PF11521.3 EGG06666.1 - 1.5 8.7 11.6 1 9.3 0.6 2.7 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF816 PF05674.7 EGG06669.1 - 0.036 13.7 0.1 0.055 13.1 0.1 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Syntaxin_2 PF14523.1 EGG06669.1 - 0.059 13.3 3.8 0.049 13.6 1.3 1.9 2 0 0 2 2 2 0 Syntaxin-like protein UBN2_3 PF14244.1 EGG06671.1 - 0.0011 18.5 0.1 0.0086 15.6 0.0 2.4 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGG06671.1 - 0.0023 17.7 0.2 0.004 16.9 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG06671.1 - 0.0042 16.6 0.5 0.007 15.9 0.4 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TcdB_N PF12918.2 EGG06671.1 - 0.066 13.3 0.8 0.92 9.6 0.1 2.5 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain THOC7 PF05615.8 EGG06672.1 - 0.09 13.0 0.1 0.09 13.0 0.1 2.5 3 0 0 3 3 3 0 Tho complex subunit 7 DUF4228 PF14009.1 EGG06672.1 - 6.8 6.7 7.2 3.3 7.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4228) F-box-like PF12937.2 EGG06673.1 - 0.084 12.6 4.0 0.98 9.1 2.8 2.5 1 1 0 1 1 1 0 F-box-like F-box PF00646.28 EGG06673.1 - 0.23 11.1 5.5 0.45 10.2 0.2 3.2 2 0 0 2 2 2 0 F-box domain TPR_12 PF13424.1 EGG06675.1 - 0.015 15.2 0.1 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGG06675.1 - 0.061 13.2 0.0 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MBOAT_2 PF13813.1 EGG06676.1 - 7.1e-14 51.6 0.6 1.7e-13 50.4 0.1 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF2098 PF09871.4 EGG06677.1 - 0.093 12.6 2.1 0.67 9.9 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Cupin_8 PF13621.1 EGG06679.1 - 5.2e-42 144.0 0.1 7.8e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGG06679.1 - 0.0066 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein zf-Mss51 PF13824.1 EGG06680.1 - 9.8e-16 57.3 0.3 2.1e-15 56.2 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 SR-25 PF10500.4 EGG06681.1 - 0.7 9.3 10.1 0.99 8.8 7.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UBN2_2 PF14227.1 EGG06682.1 - 0.0049 16.4 0.2 0.0072 15.8 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DENN PF02141.16 EGG06683.1 - 3.6e-21 75.7 0.0 1.1e-20 74.1 0.0 1.9 1 0 0 1 1 1 1 DENN (AEX-3) domain Dyp_perox PF04261.7 EGG06685.1 - 2.2e-07 29.9 0.0 5.9e-05 21.9 0.0 3.6 3 1 0 3 3 3 2 Dyp-type peroxidase family Sin_N PF04801.8 EGG06686.1 - 3.8e-10 39.1 0.0 1.2e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 Sin-like protein conserved region Amidohydro_1 PF01979.15 EGG06688.1 - 7.2e-05 22.5 0.0 7.7e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Dyp_perox PF04261.7 EGG06690.1 - 1e-12 47.4 0.0 3.8e-07 29.1 0.0 3.4 4 0 0 4 4 4 3 Dyp-type peroxidase family Tet_JBP PF12851.2 EGG06691.1 - 0.0001 21.6 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Nop14 PF04147.7 EGG06691.1 - 0.0084 14.0 1.8 0.011 13.6 1.2 1.1 1 0 0 1 1 1 1 Nop14-like family CDC27 PF09507.5 EGG06691.1 - 0.33 10.1 12.6 0.54 9.4 8.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Dicty_REP PF05086.7 EGG06695.1 - 1.2 6.7 4.2 1.7 6.2 2.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SR-25 PF10500.4 EGG06697.1 - 0.078 12.4 19.5 0.13 11.6 13.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GPAT_N PF14829.1 EGG06697.1 - 0.089 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal DnaJ PF00226.26 EGG06698.1 - 6.5e-16 57.8 3.5 1.1e-15 57.0 2.4 1.4 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_OmpA PF13436.1 EGG06698.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Neugrin PF06413.6 EGG06700.1 - 0.14 11.9 1.2 0.19 11.4 0.8 1.2 1 0 0 1 1 1 0 Neugrin COesterase PF00135.23 EGG06701.1 - 2.6e-93 313.5 0.0 3.3e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGG06701.1 - 0.0056 16.2 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold VitD-bind_III PF09164.5 EGG06701.1 - 0.2 11.2 0.1 0.41 10.2 0.1 1.4 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Lyase_aromatic PF00221.14 EGG06702.1 - 6.7e-07 28.1 0.0 8.1e-07 27.8 0.0 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Myosin_tail_1 PF01576.14 EGG06705.1 - 0.04 11.6 0.1 0.049 11.3 0.1 1.0 1 0 0 1 1 1 0 Myosin tail Rootletin PF15035.1 EGG06705.1 - 0.052 13.5 0.7 0.067 13.1 0.5 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Cep57_CLD_2 PF14197.1 EGG06705.1 - 0.15 12.0 1.2 0.24 11.3 0.8 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 CorA PF01544.13 EGG06706.1 - 0.53 9.2 1.9 1.9 7.4 0.1 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Toprim PF01751.17 EGG06709.1 - 8.3e-10 38.5 0.0 1.9e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 Toprim domain S-methyl_trans PF02574.11 EGG06711.1 - 7.4e-27 94.4 0.0 3.7e-14 52.7 0.0 2.7 2 1 0 2 2 2 2 Homocysteine S-methyltransferase DUF1469 PF07332.6 EGG06712.1 - 0.084 12.6 1.0 0.13 12.0 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Bacteriocin_IIc PF10439.4 EGG06712.1 - 0.49 10.5 24.4 0.18 11.9 2.2 2.4 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Glycoprotein_B PF00606.13 EGG06712.1 - 1 7.3 10.8 3.7 5.4 7.6 1.6 1 1 0 1 1 1 0 Herpesvirus Glycoprotein B Chlorosome_CsmC PF11098.3 EGG06712.1 - 1.2 8.8 10.9 1.9 8.1 7.6 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C FAD_binding_7 PF03441.9 EGG06713.1 - 3.1e-65 220.1 0.6 4.3e-65 219.6 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EGG06713.1 - 4.2e-28 98.1 0.0 6.6e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Uso1_p115_head PF04869.9 EGG06714.1 - 6e-58 196.0 0.0 1.1e-57 195.2 0.0 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EGG06714.1 - 2.3e-05 24.3 20.7 5.4e-05 23.1 14.3 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region FlxA PF14282.1 EGG06714.1 - 0.0019 18.1 12.2 0.0052 16.7 8.4 1.7 1 0 0 1 1 1 1 FlxA-like protein Mnd1 PF03962.10 EGG06714.1 - 0.17 11.4 12.3 0.32 10.6 8.5 1.4 1 0 0 1 1 1 0 Mnd1 family Atg14 PF10186.4 EGG06714.1 - 1.8 7.4 9.7 3.2 6.6 6.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3573 PF12097.3 EGG06714.1 - 1.8 7.0 4.4 3 6.3 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ACCA PF03255.9 EGG06714.1 - 1.9 8.0 5.0 3.8 7.0 3.5 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF724 PF05266.9 EGG06714.1 - 2.8 7.5 13.1 5 6.7 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4239 PF14023.1 EGG06714.1 - 3.1 7.1 4.1 6 6.1 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) IncA PF04156.9 EGG06714.1 - 4.6 6.8 19.4 1.3 8.5 11.0 1.8 2 0 0 2 2 2 0 IncA protein DUF4337 PF14235.1 EGG06714.1 - 5.2 6.8 7.6 10 5.9 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3225 PF11533.3 EGG06715.1 - 0.053 13.2 0.2 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3225) LIN37 PF15306.1 EGG06715.1 - 0.22 11.4 2.1 0.52 10.2 0.1 2.0 1 1 0 2 2 2 0 LIN37 DUF572 PF04502.8 EGG06716.1 - 1 8.5 13.4 1.2 8.2 9.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) OAD_gamma PF04277.8 EGG06716.1 - 2.8 8.3 7.8 4 7.8 0.0 2.6 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF826 PF05696.6 EGG06717.1 - 0.11 12.5 0.4 0.21 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF826) HALZ PF02183.13 EGG06717.1 - 0.12 12.1 1.4 0.24 11.1 1.0 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper HEAT PF02985.17 EGG06718.1 - 9.2e-34 112.4 26.2 0.0072 16.3 0.0 20.8 25 0 0 25 25 24 8 HEAT repeat HEAT_2 PF13646.1 EGG06718.1 - 1.9e-32 111.3 54.3 6.5e-09 35.9 0.2 17.0 11 2 6 17 17 15 10 HEAT repeats DUF3554 PF12074.3 EGG06718.1 - 4.4e-27 95.3 2.5 9.9e-21 74.5 0.1 5.3 5 0 0 5 5 5 3 Domain of unknown function (DUF3554) HEAT_EZ PF13513.1 EGG06718.1 - 2.8e-23 81.7 55.7 0.0013 19.1 0.2 19.7 20 3 7 27 27 23 7 HEAT-like repeat CLASP_N PF12348.3 EGG06718.1 - 9.8e-13 47.9 0.0 5.7e-05 22.5 0.1 6.5 5 1 0 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EGG06718.1 - 5.5e-09 36.3 0.0 0.34 11.3 0.0 7.7 5 2 3 8 8 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EGG06718.1 - 9.1e-09 35.4 0.0 0.0032 17.3 0.0 6.1 7 2 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EGG06718.1 - 2.6e-08 32.6 9.7 0.0051 15.1 1.8 7.0 7 1 0 7 7 7 2 Adaptin N terminal region Ipi1_N PF12333.3 EGG06718.1 - 4.1e-06 26.7 4.2 0.2 11.6 0.0 7.2 9 0 0 9 9 9 2 Rix1 complex component involved in 60S ribosome maturation RIX1 PF08167.7 EGG06718.1 - 3.2e-05 23.6 10.1 0.0015 18.2 0.0 6.8 7 0 0 7 7 7 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.7 EGG06718.1 - 0.0059 16.5 0.4 30 4.4 0.0 5.3 5 0 0 5 5 5 0 Exportin 1-like protein ParcG PF10274.4 EGG06718.1 - 0.0077 16.1 5.1 10 5.9 0.0 6.7 5 2 2 7 7 6 1 Parkin co-regulated protein Y_phosphatase2 PF03162.8 EGG06721.1 - 3.8e-53 179.2 0.0 5.7e-53 178.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EGG06721.1 - 7.6e-07 29.5 0.0 1.5e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EGG06721.1 - 0.00034 20.1 0.0 0.00057 19.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGG06721.1 - 0.0011 18.4 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Kri1 PF05178.7 EGG06722.1 - 3.6e-25 88.1 8.4 3.6e-25 88.1 5.8 5.2 6 1 0 6 6 6 1 KRI1-like family Kri1_C PF12936.2 EGG06722.1 - 2.9e-23 81.6 0.3 2.9e-23 81.6 0.2 4.1 4 0 0 4 4 4 1 KRI1-like family C-terminal Histone PF00125.19 EGG06723.1 - 1.2e-09 38.0 0.1 1.8e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGG06723.1 - 0.026 14.7 0.1 0.028 14.6 0.0 1.3 1 1 0 1 1 1 0 Kinetochore component CENP-S AsnA PF03590.10 EGG06724.1 - 0.00033 20.1 0.7 0.0007 19.1 0.5 1.5 1 0 0 1 1 1 1 Aspartate-ammonia ligase Pkinase PF00069.20 EGG06726.1 - 2.4e-66 223.5 0.0 4.4e-66 222.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG06726.1 - 4.1e-33 114.5 0.0 1.6e-31 109.3 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG06726.1 - 0.0001 21.3 0.0 0.00085 18.3 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EGG06726.1 - 0.001 18.8 1.0 0.099 12.3 0.0 3.1 3 1 1 4 4 4 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGG06726.1 - 0.03 13.1 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EGG06726.1 - 0.094 12.0 0.0 0.47 9.7 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL HflK_N PF12221.3 EGG06728.1 - 1.7 8.4 5.6 0.96 9.2 1.2 2.4 2 0 0 2 2 2 0 Bacterial membrane protein N terminal Rhomboid PF01694.17 EGG06729.1 - 1.8e-31 109.0 10.9 1.8e-31 109.0 7.6 2.0 3 0 0 3 3 3 1 Rhomboid family Trp_repressor PF01371.14 EGG06730.1 - 0.13 12.1 0.0 1.5 8.8 0.0 2.1 1 1 1 2 2 2 0 Trp repressor protein SOBP PF15279.1 EGG06731.1 - 0.0048 17.3 7.3 0.0069 16.8 5.1 1.3 1 0 0 1 1 1 1 Sine oculis-binding protein DUF572 PF04502.8 EGG06731.1 - 0.072 12.2 24.9 0.12 11.6 17.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) MDFI PF15316.1 EGG06731.1 - 0.14 12.1 4.6 0.27 11.2 3.2 1.5 1 0 0 1 1 1 0 MyoD family inhibitor Mem_trans PF03547.13 EGG06731.1 - 0.19 9.9 3.1 0.22 9.7 2.1 1.2 1 0 0 1 1 1 0 Membrane transport protein Utp14 PF04615.8 EGG06731.1 - 0.31 9.1 33.2 0.39 8.8 23.0 1.1 1 0 0 1 1 1 0 Utp14 protein Daxx PF03344.10 EGG06731.1 - 0.45 8.9 30.2 0.57 8.6 20.9 1.0 1 0 0 1 1 1 0 Daxx Family OrfB_IS605 PF01385.14 EGG06731.1 - 0.69 9.2 10.0 1.2 8.5 6.9 1.3 1 0 0 1 1 1 0 Probable transposase TATR PF03430.8 EGG06731.1 - 2.8 6.5 13.8 3.5 6.1 9.6 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator TFIIF_alpha PF05793.7 EGG06731.1 - 3.6 5.8 47.2 4.8 5.4 32.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 EGG06731.1 - 4.4 5.0 38.4 6.8 4.4 26.6 1.2 1 0 0 1 1 1 0 Nop14-like family Aldo_ket_red PF00248.16 EGG06734.1 - 2e-51 174.5 0.0 2.3e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Evr1_Alr PF04777.8 EGG06735.1 - 1.2e-26 92.4 0.4 2.2e-26 91.5 0.3 1.4 1 0 0 1 1 1 1 Erv1 / Alr family DUF4505 PF14956.1 EGG06736.1 - 4.6e-15 55.7 0.0 6.4e-15 55.2 0.0 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4505) Ribosomal_S19e PF01090.14 EGG06737.1 - 1.4e-55 186.5 0.1 1.5e-55 186.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e DUF1191 PF06697.7 EGG06738.1 - 0.012 14.4 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CoA_transf_3 PF02515.12 EGG06738.1 - 0.019 14.2 0.5 0.029 13.6 0.4 1.2 1 0 0 1 1 1 0 CoA-transferase family III Syndecan PF01034.15 EGG06738.1 - 0.021 14.4 1.4 0.036 13.7 1.0 1.3 1 0 0 1 1 1 0 Syndecan domain SOG2 PF10428.4 EGG06738.1 - 6.2 5.3 21.0 8.4 4.9 14.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein zf-CCHC PF00098.18 EGG06739.1 - 0.024 14.5 1.7 0.024 14.5 1.2 1.7 2 0 0 2 2 2 0 Zinc knuckle Pterin_4a PF01329.14 EGG06739.1 - 0.043 13.5 0.5 0.12 12.1 0.4 1.7 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase HI0933_like PF03486.9 EGG06740.1 - 0.029 12.8 0.0 0.035 12.5 0.0 1.0 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EGG06740.1 - 0.048 12.6 0.0 0.055 12.5 0.0 1.0 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 EGG06740.1 - 0.094 11.5 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EGG06740.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DFF40 PF09230.5 EGG06741.1 - 0.28 10.5 4.4 0.32 10.3 1.7 1.9 2 0 0 2 2 2 0 DNA fragmentation factor 40 kDa ALS2CR8 PF15299.1 EGG06742.1 - 0.011 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 G-alpha PF00503.15 EGG06743.1 - 1.1e-56 192.2 0.0 1.3e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGG06743.1 - 0.00042 19.6 0.0 0.00076 18.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGG06743.1 - 0.038 13.4 0.1 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RRF PF01765.14 EGG06744.1 - 0.053 12.9 0.2 0.071 12.5 0.1 1.1 1 0 0 1 1 1 0 Ribosome recycling factor HLH PF00010.21 EGG06746.1 - 1.4e-11 43.8 0.1 3e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sad1_UNC PF07738.8 EGG06747.1 - 4.4e-28 97.7 0.0 6.7e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal HALZ PF02183.13 EGG06749.1 - 0.097 12.4 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper His_Phos_1 PF00300.17 EGG06750.1 - 5e-19 68.9 0.1 1.5e-18 67.4 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) CN_hydrolase PF00795.17 EGG06751.1 - 8.2e-28 97.0 0.0 1.4e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EGG06751.1 - 3.2e-21 75.3 0.0 1.2e-20 73.4 0.0 1.9 1 1 0 1 1 1 1 NAD synthase CRT10 PF08728.5 EGG06753.1 - 0.23 9.4 3.4 0.32 8.9 2.4 1.1 1 0 0 1 1 1 0 CRT10 CybS PF05328.7 EGG06755.1 - 1.8e-42 144.1 0.0 1.9e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 CybS LEA_4 PF02987.11 EGG06756.1 - 0.036 13.9 2.0 1.3 8.9 0.3 2.5 1 1 2 3 3 3 0 Late embryogenesis abundant protein ATP-synt_10 PF05176.9 EGG06757.1 - 2.5e-60 203.8 0.0 3e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Tim17 PF02466.14 EGG06758.1 - 1e-19 70.8 0.0 1.8e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RRM_1 PF00076.17 EGG06759.1 - 8.7e-15 54.1 0.0 1.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG06759.1 - 1.3e-10 41.0 0.0 2.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG06759.1 - 4.9e-06 26.2 0.0 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGG06759.1 - 0.0042 16.8 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EGG06759.1 - 0.043 13.6 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif DUF4106 PF13388.1 EGG06759.1 - 1.4 7.7 3.7 2 7.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Glycos_transf_2 PF00535.21 EGG06760.1 - 2.2e-31 108.8 0.0 2.6e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGG06760.1 - 8.4e-12 45.3 0.0 1.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EGG06760.1 - 6.6e-06 25.4 0.0 8.5e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGG06760.1 - 0.00018 20.8 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cyto_heme_lyase PF01265.12 EGG06764.1 - 2.4e-60 204.3 0.5 2.7e-60 204.1 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Bystin PF05291.6 EGG06765.1 - 2e-130 434.1 0.5 2.3e-130 433.9 0.4 1.0 1 0 0 1 1 1 1 Bystin RP-C_C PF11800.3 EGG06768.1 - 0.0078 15.9 0.3 0.013 15.2 0.2 1.3 1 0 0 1 1 1 1 Replication protein C C-terminal region Virul_Fac PF10139.4 EGG06768.1 - 0.018 13.0 0.3 0.026 12.4 0.2 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor RepB PF07506.6 EGG06768.1 - 0.077 12.8 0.6 0.14 12.0 0.1 1.6 2 0 0 2 2 2 0 RepB plasmid partitioning protein SF3a60_bindingd PF12108.3 EGG06768.1 - 0.11 11.9 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain DUF605 PF04652.11 EGG06768.1 - 0.39 10.0 9.6 0.47 9.7 6.7 1.1 1 0 0 1 1 1 0 Vta1 like CSTF_C PF14304.1 EGG06770.1 - 0.28 10.4 1.1 4 6.7 0.1 2.5 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal L31 PF09784.4 EGG06770.1 - 0.49 10.4 6.0 1.5 8.8 4.2 1.8 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 zf-CCHC PF00098.18 EGG06770.1 - 2.7 8.0 7.9 0.14 12.0 0.9 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EGG06771.1 - 0.017 15.0 0.8 0.017 15.0 0.5 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 EGG06771.1 - 3.7 7.1 6.8 9.4 5.8 4.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Iso_dh PF00180.15 EGG06772.1 - 2.9e-119 398.0 0.0 3.4e-119 397.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_26 PF02156.10 EGG06773.1 - 0.002 17.6 1.6 0.006 16.1 1.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 26 DUF377 PF04041.8 EGG06775.1 - 0.14 10.8 0.0 0.95 8.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF377) DAP3 PF10236.4 EGG06776.1 - 4.7e-41 140.7 0.0 5.5e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EGG06776.1 - 7.1e-07 29.3 0.0 3.1e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGG06776.1 - 3.2e-05 23.6 0.0 6.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EGG06776.1 - 0.00018 21.6 0.0 0.00057 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGG06776.1 - 0.00047 19.6 0.0 0.00059 19.3 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain AAA_25 PF13481.1 EGG06776.1 - 0.0012 18.2 0.0 0.0029 17.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EGG06776.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain ArgK PF03308.11 EGG06776.1 - 0.0015 17.3 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 ArgK protein Zeta_toxin PF06414.7 EGG06776.1 - 0.003 16.7 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EGG06776.1 - 0.0046 16.4 0.1 0.013 14.9 0.1 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain KAP_NTPase PF07693.9 EGG06776.1 - 0.0069 15.4 0.0 0.0097 14.9 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Arch_ATPase PF01637.13 EGG06776.1 - 0.0077 15.9 0.0 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase NTPase_1 PF03266.10 EGG06776.1 - 0.0078 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_14 PF13173.1 EGG06776.1 - 0.0078 16.1 0.0 0.028 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGG06776.1 - 0.011 16.5 0.0 0.023 15.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGG06776.1 - 0.025 14.3 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EGG06776.1 - 0.025 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MutS_V PF00488.16 EGG06776.1 - 0.04 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 MutS domain V KTI12 PF08433.5 EGG06776.1 - 0.04 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EGG06776.1 - 0.05 13.4 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGG06776.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.10 EGG06776.1 - 0.058 13.2 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EGG06776.1 - 0.059 13.6 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGG06776.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EGG06776.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.1 EGG06776.1 - 0.15 11.6 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain BTB PF00651.26 EGG06777.1 - 2.4e-12 46.8 0.1 5.1e-10 39.3 0.0 3.0 3 0 0 3 3 3 2 BTB/POZ domain CAP_GLY PF01302.20 EGG06777.1 - 5.8e-09 35.5 0.2 4.6e-08 32.6 0.1 2.3 2 0 0 2 2 2 1 CAP-Gly domain Ribosomal_L30_N PF08079.7 EGG06778.1 - 5.9e-26 90.2 15.4 1e-25 89.5 10.7 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EGG06778.1 - 8.9e-18 63.6 1.8 1.9e-17 62.5 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e PGC7_Stella PF15549.1 EGG06778.1 - 0.091 12.7 5.0 0.15 12.0 3.5 1.3 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain HTH_5 PF01022.15 EGG06779.1 - 0.003 17.1 0.2 0.0086 15.7 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DUF3450 PF11932.3 EGG06779.1 - 0.032 13.5 27.1 0.014 14.6 6.3 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF3450) TSC22 PF01166.13 EGG06779.1 - 0.3 11.0 16.4 0.85 9.6 0.4 4.6 3 1 2 5 5 5 0 TSC-22/dip/bun family DUF4407 PF14362.1 EGG06779.1 - 8.9 5.1 15.0 1.3 7.8 4.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Auxin_repressed PF05564.7 EGG06780.1 - 1.1 9.9 5.3 8.6 6.9 3.7 2.2 1 1 0 1 1 1 0 Dormancy/auxin associated protein E1_DerP2_DerF2 PF02221.10 EGG06781.1 - 0.068 13.4 0.4 0.34 11.1 0.0 2.2 2 1 0 2 2 2 0 ML domain PilI PF10623.4 EGG06782.1 - 0.015 15.1 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 Plasmid conjugative transfer protein PilI NUDIX PF00293.23 EGG06782.1 - 0.077 12.6 0.2 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 NUDIX domain Fer4_NifH PF00142.13 EGG06782.1 - 0.18 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Abhydrolase_1 PF00561.15 EGG06783.1 - 3.4e-32 111.8 0.0 1.6e-31 109.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGG06783.1 - 1.7e-27 96.7 0.0 2.7e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG06783.1 - 9.6e-14 51.3 0.0 7.7e-13 48.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 EGG06783.1 - 0.0016 17.1 0.0 0.0027 16.3 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_4 PF08386.5 EGG06783.1 - 0.003 17.4 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.9 EGG06783.1 - 0.008 14.6 0.0 0.012 14.1 0.0 1.3 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EGG06783.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.6 1 1 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 EGG06783.1 - 0.03 13.5 0.0 7.3 5.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 EGG06783.1 - 0.058 12.9 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase Pkinase PF00069.20 EGG06787.1 - 1.2e-46 158.9 0.7 7.5e-46 156.3 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG06787.1 - 3.2e-20 72.3 0.1 1.1e-19 70.5 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG06787.1 - 3.1e-07 29.6 0.0 5.9e-07 28.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGG06787.1 - 0.00022 20.3 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGG06787.1 - 0.0005 19.8 0.1 0.00069 19.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGG06787.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.6 EGG06787.1 - 0.065 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) KH_3 PF13014.1 EGG06787.1 - 0.11 12.2 1.1 0.28 10.8 0.8 1.7 1 0 0 1 1 1 0 KH domain Histone PF00125.19 EGG06788.1 - 7.9e-26 89.9 0.0 9.5e-26 89.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGG06788.1 - 1.7e-05 24.7 0.0 2.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Tnp_DNA_bind PF14706.1 EGG06789.1 - 0.13 12.0 0.6 0.52 10.0 0.0 2.3 3 0 0 3 3 3 0 Transposase DNA-binding Abhydrolase_3 PF07859.8 EGG06792.1 - 3.1e-30 105.3 0.0 4.3e-22 78.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF3608 PF12257.3 EGG06793.1 - 1.7e-55 187.9 0.1 2.4e-55 187.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EGG06793.1 - 2.8e-06 26.9 0.0 7.7e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Mito_carr PF00153.22 EGG06794.1 - 3e-78 257.6 1.3 7e-26 89.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.11 EGG06794.1 - 0.041 13.7 0.3 2.1 8.1 0.0 2.9 3 0 0 3 3 3 0 Colicin V production protein FF PF01846.14 EGG06796.1 - 7.9e-32 108.9 40.8 3.4e-12 46.1 0.4 6.7 7 0 0 7 7 7 5 FF domain WW PF00397.21 EGG06796.1 - 5e-13 48.6 14.2 1.9e-08 33.9 2.3 3.0 2 0 0 2 2 2 2 WW domain FYVE PF01363.16 EGG06798.1 - 2.5e-14 52.9 5.3 3e-14 52.6 3.7 1.1 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 EGG06798.1 - 0.0066 16.2 9.1 0.0066 16.2 6.3 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger zf-RING_5 PF14634.1 EGG06798.1 - 0.045 13.4 7.4 0.12 12.0 5.2 1.8 1 1 0 1 1 1 0 zinc-RING finger domain DUF325 PF03804.8 EGG06798.1 - 0.14 11.8 0.2 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Viral domain of unknown function XPA_N PF01286.13 EGG06798.1 - 0.92 9.2 11.5 4.7 6.9 0.1 2.5 2 0 0 2 2 2 0 XPA protein N-terminal IBR PF01485.16 EGG06798.1 - 1.7 8.6 11.5 0.12 12.2 3.7 1.9 1 1 1 2 2 2 0 IBR domain FYVE_2 PF02318.11 EGG06798.1 - 6.9 6.6 6.9 8.6 6.2 4.8 1.3 1 1 0 1 1 1 0 FYVE-type zinc finger LRR_4 PF12799.2 EGG06800.1 - 1.8e-06 27.4 18.6 9.5e-05 21.9 4.2 4.4 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG06800.1 - 3.3e-06 26.7 16.1 9.9e-06 25.2 6.1 3.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EGG06800.1 - 2.9e-05 23.5 15.8 0.53 10.5 0.2 6.0 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EGG06800.1 - 0.44 10.9 13.2 29 5.4 0.6 5.9 6 0 0 6 6 6 0 Leucine rich repeat Alpha_kinase PF02816.13 EGG06803.1 - 0.00034 20.3 2.2 0.00075 19.2 1.5 1.7 1 1 0 1 1 1 1 Alpha-kinase family DUF4297 PF14130.1 EGG06803.1 - 0.012 15.5 0.1 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) SKI PF01202.17 EGG06806.1 - 0.01 15.6 0.1 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 Shikimate kinase GFA PF04828.9 EGG06807.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme TFIIF_beta PF02270.10 EGG06808.1 - 2.6e-63 214.4 0.0 3.3e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit TAFH PF07531.9 EGG06810.1 - 0.058 13.0 0.2 4.8 6.8 0.0 2.8 3 0 0 3 3 3 0 NHR1 homology to TAF SpoVIF PF14069.1 EGG06810.1 - 0.089 12.5 0.1 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Stage VI sporulation protein F FAM196 PF15265.1 EGG06812.1 - 5.3 6.1 20.7 7.1 5.7 14.4 1.1 1 0 0 1 1 1 0 FAM196 family Peptidase_S64 PF08192.6 EGG06812.1 - 5.4 5.2 13.8 7 4.8 9.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.4 EGG06812.1 - 8 4.6 21.3 9.5 4.3 14.8 1.1 1 0 0 1 1 1 0 Transmembrane protein VIT1 PF01988.14 EGG06813.1 - 3.1e-51 173.8 3.8 3.4e-51 173.7 2.6 1.0 1 0 0 1 1 1 1 VIT family DUF4536 PF15055.1 EGG06813.1 - 0.08 13.0 0.5 17 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) DUF308 PF03729.8 EGG06813.1 - 0.93 9.5 9.9 0.17 11.9 2.2 2.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Profilin PF00235.14 EGG06816.1 - 5.8e-38 129.7 0.1 6.4e-38 129.5 0.1 1.0 1 0 0 1 1 1 1 Profilin Myb_DNA-bind_4 PF13837.1 EGG06817.1 - 0.025 14.7 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain KAR9 PF08580.5 EGG06817.1 - 2 6.5 3.7 2.4 6.3 2.6 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TFIIE_beta PF02186.10 EGG06819.1 - 0.033 14.1 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 TFIIE beta subunit core domain Cyt-b5 PF00173.23 EGG06820.1 - 9e-20 70.2 0.0 1.2e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Neuropeptide_S PF14993.1 EGG06821.1 - 0.14 11.8 0.5 21 4.8 0.0 2.4 2 0 0 2 2 2 0 Neuropeptide S precursor protein Cutinase PF01083.17 EGG06822.1 - 1.6e-29 102.9 2.4 1.9e-29 102.6 1.7 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 EGG06822.1 - 0.01 15.7 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG06822.1 - 0.029 14.1 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 EGG06822.1 - 0.088 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Thioesterase PF00975.15 EGG06822.1 - 0.092 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Pmp3 PF01679.12 EGG06823.1 - 1.5e-12 46.9 5.7 2.4e-12 46.3 4.0 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SLD3 PF08639.5 EGG06823.1 - 0.15 10.6 7.9 0.18 10.3 5.5 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF3359 PF11839.3 EGG06824.1 - 0.047 14.0 0.6 0.052 13.8 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3359) ICL PF00463.16 EGG06825.1 - 0.0087 14.3 0.0 0.026 12.7 0.0 1.7 2 0 0 2 2 2 1 Isocitrate lyase family CheW PF01584.14 EGG06825.1 - 0.071 12.5 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 CheW-like domain Proteasome PF00227.21 EGG06826.1 - 1e-51 174.9 0.0 1.2e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGG06826.1 - 1.5e-13 49.7 1.6 3.7e-13 48.5 0.0 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature COesterase PF00135.23 EGG06827.1 - 6.8e-98 328.6 0.0 9e-98 328.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EGG06827.1 - 0.0028 16.9 0.4 0.0042 16.3 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EGG06827.1 - 0.0031 17.1 0.1 0.0059 16.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold CAP59_mtransfer PF11735.3 EGG06828.1 - 1.3e-18 67.1 0.0 1.9e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 FAM124 PF15067.1 EGG06828.1 - 0.11 11.9 0.1 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 FAM124 family DUF4027 PF13219.1 EGG06829.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) BOP1NT PF08145.7 EGG06830.1 - 3.5e-104 348.1 4.2 5.1e-104 347.6 2.9 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EGG06830.1 - 4.1e-19 67.6 0.2 0.0013 18.5 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat IKI3 PF04762.7 EGG06830.1 - 0.0046 14.8 0.0 0.0064 14.3 0.0 1.1 1 0 0 1 1 1 1 IKI3 family PI-PLC-X PF00388.14 EGG06831.1 - 1.1e-12 47.6 0.1 4.6e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain DUF2684 PF10885.3 EGG06832.1 - 0.027 14.3 2.3 2.3 8.1 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2684) DUF947 PF06102.7 EGG06833.1 - 0.0024 17.7 5.1 0.0024 17.7 3.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF947) DUF4491 PF14898.1 EGG06834.1 - 0.86 9.7 3.7 4.2 7.5 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4491) Tetraspannin PF00335.15 EGG06834.1 - 8 5.6 15.1 1.9 7.7 4.7 2.5 1 1 1 2 2 2 0 Tetraspanin family TPP_enzyme_N PF02776.13 EGG06838.1 - 5.1e-37 127.0 0.0 8e-37 126.3 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGG06838.1 - 1.6e-21 76.4 0.1 1.3e-20 73.5 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EGG06838.1 - 2.2e-14 53.3 0.0 3.9e-13 49.2 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peripla_BP_4 PF13407.1 EGG06838.1 - 0.02 14.2 0.0 0.056 12.7 0.0 1.6 2 0 0 2 2 2 0 Periplasmic binding protein domain DXP_synthase_N PF13292.1 EGG06838.1 - 0.028 13.3 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_N PF02776.13 EGG06839.1 - 5.9e-37 126.7 0.0 8.8e-37 126.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGG06839.1 - 3.2e-22 78.7 0.2 1.6e-21 76.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EGG06839.1 - 1.2e-13 50.8 0.0 9.8e-13 47.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EGG06839.1 - 0.0028 16.6 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Peripla_BP_4 PF13407.1 EGG06839.1 - 0.015 14.6 0.0 0.045 13.1 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding protein domain Abhydrolase_6 PF12697.2 EGG06840.1 - 5.1e-19 69.0 0.0 6.9e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG06840.1 - 4.7e-13 49.2 0.0 1.4e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG06840.1 - 1.2e-09 38.0 0.0 3e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGG06840.1 - 0.0054 16.2 0.1 0.044 13.2 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EGG06840.1 - 0.0081 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EGG06840.1 - 0.031 14.4 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF2048 PF09752.4 EGG06840.1 - 0.042 12.7 0.0 0.087 11.6 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Esterase PF00756.15 EGG06840.1 - 0.081 12.3 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Putative esterase UPF0227 PF05728.7 EGG06840.1 - 0.13 11.9 0.0 0.92 9.2 0.0 2.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0227) Auxin_repressed PF05564.7 EGG06841.1 - 1.9 9.0 8.1 0.14 12.7 0.3 2.2 2 0 0 2 2 2 0 Dormancy/auxin associated protein Pkinase PF00069.20 EGG06842.1 - 1.9e-61 207.5 0.0 2.4e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG06842.1 - 1.3e-33 116.1 0.0 1.7e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG06842.1 - 0.08 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Iso_dh PF00180.15 EGG06843.1 - 3.9e-82 275.9 0.0 1.2e-81 274.4 0.0 1.7 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase OPT PF03169.10 EGG06846.1 - 7.7e-60 203.0 37.5 1.8e-57 195.2 26.0 3.1 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Lactamase_B_2 PF12706.2 EGG06849.1 - 2.6e-15 56.4 1.2 4.4e-15 55.7 0.8 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGG06849.1 - 1.6e-09 37.6 1.6 3.2e-09 36.7 1.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF3835 PF12927.2 EGG06850.1 - 0.09 13.7 0.3 0.38 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) AAA_21 PF13304.1 EGG06852.1 - 0.42 10.5 6.8 0.5 10.2 4.7 1.1 1 0 0 1 1 1 0 AAA domain Drc1-Sld2 PF11719.3 EGG06852.1 - 1.5 7.7 17.2 2.1 7.3 12.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Hce2 PF14856.1 EGG06853.1 - 0.051 13.4 0.2 0.067 13.1 0.1 1.2 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor GFA PF04828.9 EGG06854.1 - 0.045 13.6 0.5 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nop14 PF04147.7 EGG06858.1 - 0.098 10.5 9.7 0.099 10.5 6.7 1.2 1 0 0 1 1 1 0 Nop14-like family Atrophin-1 PF03154.10 EGG06858.1 - 0.14 10.2 4.4 0.15 10.2 3.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family Actin PF00022.14 EGG06861.1 - 2.4e-117 391.7 0.0 2.7e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGG06861.1 - 0.0027 16.3 0.3 1 7.8 0.0 2.5 3 0 0 3 3 3 2 MreB/Mbl protein Spo12 PF05032.7 EGG06862.1 - 2.1e-09 36.8 0.2 4.2e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Spo12 family DUF2645 PF10840.3 EGG06863.1 - 0.013 15.6 0.6 0.019 15.1 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2645) DUF3684 PF12449.3 EGG06864.1 - 0 1046.5 0.0 0 1046.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EGG06864.1 - 0.0018 17.9 0.0 0.0053 16.4 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGG06864.1 - 0.0091 15.7 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAD_binding_1 PF00667.15 EGG06865.1 - 1.4e-28 99.8 0.4 2.4e-19 69.6 0.0 3.1 2 1 1 3 3 3 2 FAD binding domain NAD_binding_1 PF00175.16 EGG06865.1 - 5.9e-08 33.2 0.0 2.4e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain cwf21 PF08312.7 EGG06866.1 - 1.1e-13 50.7 8.3 1.1e-13 50.7 5.8 1.9 2 0 0 2 2 2 1 cwf21 domain NOA36 PF06524.7 EGG06869.1 - 0.041 13.1 2.8 0.055 12.7 1.9 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EGG06869.1 - 0.06 12.8 9.6 0.1 12.1 6.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EGG06869.1 - 0.064 13.5 14.5 0.13 12.5 10.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3496 PF12001.3 EGG06869.1 - 0.075 13.2 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) DUF4611 PF15387.1 EGG06869.1 - 0.085 13.0 6.1 0.18 11.9 4.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Tim54 PF11711.3 EGG06869.1 - 0.11 11.0 7.7 0.15 10.6 5.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EBV-NA3 PF05009.7 EGG06869.1 - 0.15 11.2 8.1 0.12 11.6 4.4 1.6 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) TRAP_alpha PF03896.11 EGG06869.1 - 0.36 9.7 3.2 0.61 9.0 2.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Herpes_gE PF02480.11 EGG06869.1 - 0.48 8.6 2.4 0.64 8.2 1.7 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FAM176 PF14851.1 EGG06869.1 - 0.63 9.7 4.6 1.1 8.8 3.2 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 EGG06869.1 - 0.71 7.8 7.4 0.72 7.8 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.6 EGG06869.1 - 0.99 9.0 6.4 1.6 8.3 4.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sigma70_ner PF04546.8 EGG06869.1 - 2.1 7.9 11.3 2.1 7.9 6.0 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.6 EGG06869.1 - 5.1 6.8 10.5 7.7 6.3 7.1 1.6 1 1 0 1 1 1 0 RXT2-like, N-terminal HEAT PF02985.17 EGG06871.1 - 0.015 15.2 0.2 0.18 11.9 0.1 2.5 2 0 0 2 2 2 0 HEAT repeat Spexin PF15171.1 EGG06871.1 - 0.033 14.1 0.1 0.05 13.6 0.1 1.2 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin HEAT_EZ PF13513.1 EGG06871.1 - 0.11 13.0 1.1 1.8 9.1 0.2 2.5 2 1 1 3 3 3 0 HEAT-like repeat DS PF01916.12 EGG06875.1 - 2.5e-129 430.6 0.0 2.9e-129 430.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Ammonium_transp PF00909.16 EGG06876.1 - 4.9e-99 331.5 24.8 5.9e-99 331.2 17.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Snf7 PF03357.16 EGG06877.1 - 2.7e-38 131.0 16.6 3.2e-38 130.8 11.5 1.0 1 0 0 1 1 1 1 Snf7 AAA_12 PF13087.1 EGG06877.1 - 0.032 13.6 2.2 0.046 13.0 1.5 1.2 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.15 EGG06877.1 - 0.032 13.9 12.5 0.064 13.0 0.0 3.2 2 1 0 2 2 2 0 Prefoldin subunit NgoMIV_restric PF09015.5 EGG06877.1 - 0.046 12.7 0.3 0.056 12.4 0.2 1.1 1 0 0 1 1 1 0 NgoMIV restriction enzyme Mod_r PF07200.8 EGG06877.1 - 0.081 12.8 10.7 0.031 14.1 3.6 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DMPK_coil PF08826.5 EGG06877.1 - 0.13 12.1 0.2 0.13 12.1 0.1 2.4 3 1 0 3 3 3 0 DMPK coiled coil domain like Prefoldin PF02996.12 EGG06877.1 - 0.14 11.7 9.9 1.9 8.1 1.9 3.0 2 1 1 3 3 3 0 Prefoldin subunit Mnd1 PF03962.10 EGG06877.1 - 0.15 11.7 11.6 0.38 10.3 8.1 1.6 1 1 0 1 1 1 0 Mnd1 family NPV_P10 PF05531.7 EGG06877.1 - 0.16 12.2 5.1 4.3 7.6 1.1 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein NuA4 PF09340.5 EGG06877.1 - 0.19 11.3 3.8 0.26 10.9 1.2 2.3 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF342 PF03961.8 EGG06877.1 - 0.21 9.9 12.3 0.51 8.6 7.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF2730 PF10805.3 EGG06877.1 - 0.31 10.8 8.2 4.2 7.1 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) TBPIP PF07106.8 EGG06877.1 - 0.41 10.1 11.5 0.63 9.5 2.7 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_TATA_bd PF12325.3 EGG06877.1 - 0.68 9.6 12.2 0.24 11.1 4.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DSBA PF01323.15 EGG06877.1 - 0.87 9.1 4.3 1.1 8.7 2.8 1.3 1 1 0 1 1 1 0 DSBA-like thioredoxin domain DUF4407 PF14362.1 EGG06877.1 - 1 8.2 6.5 1.2 7.9 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.1 EGG06877.1 - 1.8 8.5 13.7 3.4 7.6 6.1 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF948 PF06103.6 EGG06877.1 - 2.3 8.1 5.8 15 5.5 2.5 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 EGG06877.1 - 2.7 6.9 10.6 5 6.0 7.3 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 SlyX PF04102.7 EGG06877.1 - 2.9 8.3 0.0 2.9 8.3 0.0 3.6 2 1 1 3 3 3 0 SlyX Syntaxin-6_N PF09177.6 EGG06877.1 - 3.5 8.0 6.1 5.7 7.4 1.5 2.6 1 1 0 2 2 2 0 Syntaxin 6, N-terminal GvpK PF05121.7 EGG06877.1 - 8.2 6.3 10.6 1.6 8.6 1.5 2.9 2 1 1 3 3 3 0 Gas vesicle protein K Alpha_kinase PF02816.13 EGG06879.1 - 2.6e-06 27.2 0.4 6.3e-05 22.7 0.1 2.5 2 0 0 2 2 2 1 Alpha-kinase family CI-B14_5a PF07347.7 EGG06879.1 - 0.023 14.4 0.1 0.062 13.0 0.0 1.7 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Myb_DNA-bind_3 PF12776.2 EGG06881.1 - 0.25 11.9 1.4 0.98 10.0 0.8 1.8 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Ras PF00071.17 EGG06882.1 - 4.5e-34 117.1 0.0 5.5e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG06882.1 - 2e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG06882.1 - 0.0011 18.2 0.0 0.0015 17.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 EGG06882.1 - 0.052 13.0 0.0 0.075 12.5 0.0 1.3 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Glyco_hydro_18 PF00704.23 EGG06884.1 - 4.6e-64 217.0 0.2 5.4e-64 216.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LAT PF15234.1 EGG06885.1 - 0.42 10.0 3.7 0.44 9.9 2.6 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells DUF947 PF06102.7 EGG06886.1 - 5e-39 133.8 17.8 5e-39 133.8 12.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF947) Trypan_PARP PF05887.6 EGG06886.1 - 0.0086 15.9 5.5 0.018 14.8 3.8 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF3456 PF11938.3 EGG06886.1 - 0.047 13.6 7.1 0.11 12.4 4.9 1.7 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP tRNA_lig_kinase PF08303.6 EGG06886.1 - 0.49 10.2 5.0 0.11 12.3 0.4 2.1 2 1 1 3 3 3 0 tRNA ligase kinase domain HALZ PF02183.13 EGG06886.1 - 4.8 6.9 10.0 1.2 8.9 0.1 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Hex_IIIa PF02455.11 EGG06886.1 - 6.7 5.2 12.3 11 4.6 8.4 1.4 1 1 0 1 1 1 0 Hexon-associated protein (IIIa) DUF543 PF04418.7 EGG06887.1 - 3.8e-10 39.5 0.1 4.4e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Lipase_3 PF01764.20 EGG06888.1 - 2e-17 63.1 0.0 3.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) MAP7 PF05672.6 EGG06888.1 - 0.0014 18.0 2.3 0.0023 17.3 1.6 1.3 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Abhydrolase_5 PF12695.2 EGG06888.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 EGG06888.1 - 0.051 12.8 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) COesterase PF00135.23 EGG06889.1 - 7.7e-30 104.1 0.0 1e-27 97.0 0.0 2.8 1 1 1 2 2 2 2 Carboxylesterase family COesterase PF00135.23 EGG06890.1 - 1.1e-27 97.0 0.1 1.1e-27 96.9 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGG06890.1 - 0.00048 19.7 0.0 0.0005 19.6 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGG06890.1 - 0.0061 15.7 0.0 0.0061 15.7 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EGG06891.1 - 1.2e-13 50.6 0.0 1.7e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family bZIP_1 PF00170.16 EGG06893.1 - 9.5e-12 44.7 9.4 2.1e-11 43.5 6.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 EGG06893.1 - 2.4e-08 34.3 0.6 2.4e-08 34.3 0.4 4.6 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EGG06893.1 - 1e-05 25.2 8.7 1e-05 25.2 6.0 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EGG06893.1 - 0.0029 17.8 2.2 0.0029 17.8 1.6 3.1 3 0 0 3 3 3 1 bZIP Maf transcription factor SET PF00856.23 EGG06895.1 - 1.7e-05 25.2 0.0 1.7e-05 25.2 0.0 3.5 3 1 0 3 3 3 1 SET domain Zip PF02535.17 EGG06896.1 - 0.11 11.4 6.5 0.12 11.3 4.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PWWP PF00855.12 EGG06898.1 - 4.5e-07 29.9 0.0 7.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 PWWP domain HTH_33 PF13592.1 EGG06902.1 - 0.012 15.0 1.1 0.14 11.6 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix DUF2316 PF10078.4 EGG06907.1 - 0.0059 16.5 0.0 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2316) PhaP_Bmeg PF09602.5 EGG06907.1 - 0.16 11.8 0.0 0.57 9.9 0.0 1.9 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DNA_pol3_tau_4 PF12168.3 EGG06909.1 - 0.073 13.4 0.9 0.12 12.7 0.6 1.3 1 0 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding Alpha_E3_glycop PF01563.11 EGG06910.1 - 0.3 10.9 2.5 10 6.0 1.4 2.4 2 0 0 2 2 2 0 Alphavirus E3 glycoprotein RNase_H2-Ydr279 PF09468.5 EGG06910.1 - 0.56 9.3 9.9 0.84 8.7 6.8 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF4544 PF15077.1 EGG06910.1 - 3.5 7.0 7.2 3.7 6.9 4.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4544) Neur_chan_memb PF02932.11 EGG06910.1 - 6.2 6.6 7.0 8.6 6.1 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ATP_bind_1 PF03029.12 EGG06912.1 - 1.2e-79 267.2 0.0 1.4e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EGG06912.1 - 1.2e-05 26.1 0.0 2.8e-05 24.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain CbiA PF01656.18 EGG06912.1 - 0.00012 21.6 0.0 0.00035 20.0 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 EGG06912.1 - 0.0003 20.2 0.0 0.0075 15.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EGG06912.1 - 0.0009 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EGG06912.1 - 0.00092 18.7 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 EGG06912.1 - 0.0015 18.0 0.0 0.0051 16.2 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 EGG06912.1 - 0.0021 17.9 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EGG06912.1 - 0.0032 17.1 0.0 0.0081 15.8 0.0 1.7 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EGG06912.1 - 0.006 16.7 0.1 0.02 15.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGG06912.1 - 0.0087 16.0 0.0 0.023 14.7 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EGG06912.1 - 0.01 16.1 0.2 0.026 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EGG06912.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgK PF03308.11 EGG06912.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 EGG06912.1 - 0.016 15.7 0.0 0.72 10.3 0.0 3.0 3 0 0 3 3 3 0 Miro-like protein RNA_helicase PF00910.17 EGG06912.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EGG06912.1 - 0.022 14.2 0.1 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGG06912.1 - 0.028 14.3 0.0 0.081 12.8 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGG06912.1 - 0.04 13.0 0.1 0.29 10.2 0.1 2.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 EGG06912.1 - 0.05 12.9 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain CobU PF02283.11 EGG06912.1 - 0.07 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase IstB_IS21 PF01695.12 EGG06912.1 - 0.075 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EGG06912.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Septin PF00735.13 EGG06912.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Septin KTI12 PF08433.5 EGG06912.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Ribosomal_S3Ae PF01015.13 EGG06914.1 - 8.4e-83 276.4 4.2 1e-82 276.2 2.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF1092 PF06485.6 EGG06914.1 - 0.011 14.7 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) MRP-L27 PF09809.4 EGG06914.1 - 0.052 13.1 0.2 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L27 mRNA_cap_C PF03919.10 EGG06914.1 - 0.061 13.6 0.7 0.099 12.9 0.1 1.7 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain Abhydro_lipase PF04083.11 EGG06914.1 - 0.098 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Allexi_40kDa PF05549.6 EGG06915.1 - 0.023 14.0 0.3 0.48 9.6 0.3 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF615 PF04751.9 EGG06915.1 - 0.044 13.4 0.0 3.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF615) Enkurin PF13864.1 EGG06915.1 - 0.19 11.9 0.4 0.46 10.7 0.3 1.7 1 0 0 1 1 1 0 Calmodulin-binding AAA_12 PF13087.1 EGG06916.1 - 3.1e-30 105.0 0.2 5.6e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain TF_AP-2 PF03299.9 EGG06916.1 - 0.14 11.6 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 Transcription factor AP-2 Cutinase PF01083.17 EGG06919.1 - 6.2e-31 107.5 4.0 9.2e-31 106.9 2.8 1.3 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 EGG06919.1 - 0.00069 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 EGG06919.1 - 0.0015 18.0 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_8 PF06259.7 EGG06919.1 - 0.052 13.0 0.1 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_9 PF10081.4 EGG06919.1 - 0.17 10.5 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Lactamase_B_2 PF12706.2 EGG06920.1 - 1.6e-13 50.6 0.0 2.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGG06920.1 - 2e-09 37.3 0.0 3.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF4494 PF14902.1 EGG06921.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4494) E1-E2_ATPase PF00122.15 EGG06922.1 - 1.3e-61 207.6 1.6 5.5e-60 202.2 1.1 2.0 1 1 0 1 1 1 1 E1-E2 ATPase DUF2127 PF09900.4 EGG06922.1 - 0.005 16.8 0.9 0.011 15.7 0.3 1.8 1 1 0 1 1 1 1 Predicted membrane protein (DUF2127) FliC PF12445.3 EGG06923.1 - 2.7 8.1 10.0 1.2e+02 2.8 0.0 3.1 1 1 2 3 3 3 0 Flagellin protein Paf1 PF03985.8 EGG06925.1 - 0.012 14.4 4.5 0.02 13.6 3.1 1.3 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.11 EGG06925.1 - 3.3 6.6 6.9 5.9 5.8 4.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 EGG06925.1 - 5.2 6.5 8.9 11 5.5 6.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin GHMP_kinases_N PF00288.21 EGG06929.1 - 3.1e-08 33.5 0.0 5.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cytochrom_B562 PF07361.6 EGG06930.1 - 0.023 15.0 0.6 0.056 13.8 0.4 1.7 1 1 0 1 1 1 0 Cytochrome b562 IGPD PF00475.13 EGG06931.1 - 7.8e-55 184.7 1.1 1.1e-54 184.2 0.8 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DEAD PF00270.24 EGG06932.1 - 3.5e-35 120.9 0.0 6.8e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG06932.1 - 3.7e-19 68.3 0.0 9.3e-18 63.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EGG06932.1 - 1e-16 60.2 0.0 2.3e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EGG06932.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4094 PF13334.1 EGG06934.1 - 0.038 14.3 3.7 0.092 13.1 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) MAD PF05557.8 EGG06934.1 - 0.41 8.6 3.2 0.58 8.1 2.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF2015 PF09435.5 EGG06935.1 - 5.8e-11 42.2 0.2 7.5e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Hexapep PF00132.19 EGG06937.1 - 0.0026 17.1 0.1 0.033 13.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Chitin_synth_1 PF01644.12 EGG06938.1 - 1.1e-63 213.9 0.0 1.8e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EGG06938.1 - 6e-26 90.9 0.1 7.5e-21 74.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EGG06938.1 - 8e-26 89.5 0.0 1.6e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EGG06938.1 - 6e-12 45.6 1.8 1.4e-11 44.4 0.8 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGG06938.1 - 6.5e-11 42.4 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Arrestin_C PF02752.17 EGG06939.1 - 4.4e-15 55.9 2.4 1.3e-14 54.5 0.1 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGG06939.1 - 0.011 15.5 1.5 1.1 9.1 0.0 3.3 3 1 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain MCM PF00493.18 EGG06941.1 - 4.7e-88 295.1 6.5 2.7e-72 243.3 2.2 3.1 1 1 1 2 2 2 2 MCM2/3/5 family Mg_chelatase PF01078.16 EGG06941.1 - 4.2e-07 29.3 0.0 8.1e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.1 EGG06941.1 - 5e-06 26.9 0.0 1.4e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Sigma54_activat PF00158.21 EGG06941.1 - 0.021 14.2 0.1 0.064 12.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Polyoma_coat2 PF00761.15 EGG06941.1 - 0.15 11.5 0.6 0.28 10.6 0.4 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein zf-C3HC4_2 PF13923.1 EGG06943.1 - 0.12 12.3 2.7 0.15 12.0 0.6 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TerY-C PF15616.1 EGG06946.1 - 0.056 13.3 2.9 0.11 12.3 2.0 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain DUF3987 PF13148.1 EGG06946.1 - 0.11 11.0 0.1 0.33 9.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) F-box PF00646.28 EGG06947.1 - 0.075 12.7 0.6 0.38 10.4 0.4 2.2 1 1 0 1 1 1 0 F-box domain Cyclin_N PF00134.18 EGG06949.1 - 1.1e-05 25.0 0.3 1.9e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Aminotran_1_2 PF00155.16 EGG06950.1 - 3.7e-41 141.2 0.0 5.5e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGG06950.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase TYW3 PF02676.9 EGG06950.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TYW3 RPAP3_C PF13877.1 EGG06951.1 - 0.028 14.3 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Aminotran_1_2 PF00155.16 EGG06952.1 - 1e-36 126.6 0.0 1.4e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGG06952.1 - 0.085 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase PASTA PF03793.14 EGG06953.1 - 0.18 11.4 1.0 0.29 10.8 0.7 1.3 1 0 0 1 1 1 0 PASTA domain NPR3 PF03666.8 EGG06954.1 - 8.6e-22 77.2 0.3 1.6e-21 76.3 0.2 1.4 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 HMG_box PF00505.14 EGG06955.1 - 0.0063 16.7 0.4 0.21 11.8 0.1 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box WD40 PF00400.27 EGG06958.1 - 2.8e-45 150.6 16.3 6.4e-09 35.3 0.0 12.7 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.7 EGG06958.1 - 1.1e-26 92.8 1.0 1.8e-26 92.1 0.7 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EGG06958.1 - 6.4e-05 22.7 5.8 0.63 9.7 0.2 5.6 2 2 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EGG06958.1 - 0.00038 20.0 0.2 11 5.8 0.0 5.5 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.1 EGG06958.1 - 0.013 14.5 0.1 0.08 11.9 0.0 2.3 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nbas_N PF15492.1 EGG06958.1 - 0.024 13.7 1.1 1.9 7.5 0.0 4.0 3 3 2 5 5 5 0 Neuroblastoma-amplified sequence, N terminal RRM_1 PF00076.17 EGG06958.1 - 0.061 12.9 0.1 0.18 11.4 0.1 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIE_alpha PF02002.12 EGG06959.1 - 1.1e-15 56.9 0.6 2e-15 56.1 0.4 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EGG06959.1 - 0.0014 17.9 0.9 0.0026 17.0 0.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding GntR PF00392.16 EGG06959.1 - 0.02 14.3 0.2 0.036 13.4 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Zn_Tnp_IS1595 PF12760.2 EGG06959.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain GNAT_acetyltr_2 PF13718.1 EGG06959.1 - 0.092 12.0 0.1 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 zf-FPG_IleRS PF06827.9 EGG06959.1 - 0.32 10.6 1.7 1.6 8.4 1.3 2.1 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS zf-RING_4 PF14570.1 EGG06959.1 - 0.56 9.8 3.9 1.5 8.4 0.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain GST_N_2 PF13409.1 EGG06960.1 - 1.8e-21 75.9 0.0 3.9e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGG06960.1 - 1.3e-14 53.7 0.0 2.3e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGG06960.1 - 2.5e-09 37.0 0.0 6e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGG06960.1 - 1.2e-05 25.4 0.0 0.0019 18.4 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGG06960.1 - 5.9e-05 23.4 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WD40 PF00400.27 EGG06962.1 - 3.7e-24 83.6 16.5 8.4e-09 34.9 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Rax2 PF12768.2 EGG06962.1 - 0.013 14.6 0.8 0.045 12.9 0.0 2.0 2 0 0 2 2 2 0 Cortical protein marker for cell polarity DPPIV_N PF00930.16 EGG06962.1 - 0.017 13.6 1.6 1.4 7.4 0.1 3.0 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.6 EGG06962.1 - 0.02 14.5 0.4 0.7 9.5 0.0 2.7 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A SID-1_RNA_chan PF13965.1 EGG06963.1 - 7.8 4.5 7.9 11 4.0 5.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HSF_DNA-bind PF00447.12 EGG06964.1 - 5.1e-26 90.8 2.2 5.5e-26 90.7 1.5 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Cdc6_C PF09079.6 EGG06964.1 - 0.039 13.6 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 CDC6, C terminal UQ_con PF00179.21 EGG06965.1 - 1.2e-51 173.8 0.0 1.3e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGG06965.1 - 0.00025 20.7 0.0 0.0003 20.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGG06965.1 - 0.0049 16.7 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EGG06965.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain PSS PF03034.10 EGG06966.1 - 5e-96 321.4 13.3 7.7e-96 320.7 9.2 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase Reo_sigmaC PF04582.7 EGG06967.1 - 0.0085 15.3 2.3 0.058 12.5 1.0 2.0 2 0 0 2 2 2 1 Reovirus sigma C capsid protein DUF922 PF06037.6 EGG06967.1 - 0.74 9.1 4.7 0.49 9.7 1.1 2.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF922) Cript PF10235.4 EGG06969.1 - 3.7e-16 59.2 20.0 1.1e-11 44.8 7.5 2.7 1 1 2 3 3 3 2 Microtubule-associated protein CRIPT stn_TNFRSF12A PF12191.3 EGG06969.1 - 0.018 15.1 3.3 0.03 14.3 2.3 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain YuzL PF14115.1 EGG06969.1 - 0.065 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 YuzL-like protein PHF5 PF03660.9 EGG06969.1 - 0.073 13.1 5.8 0.057 13.4 2.2 2.0 2 0 0 2 2 2 0 PHF5-like protein DUF2797 PF10977.3 EGG06969.1 - 0.13 11.8 2.0 0.23 11.0 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) DUF1272 PF06906.6 EGG06969.1 - 0.26 11.1 5.2 4.3 7.2 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-ribbon_3 PF13248.1 EGG06969.1 - 0.28 10.4 10.1 0.93 8.7 2.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 EGG06969.1 - 0.32 10.8 13.2 1.8 8.4 4.8 2.8 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EGG06969.1 - 2.2 7.8 15.6 5.4 6.6 0.2 3.2 2 1 0 2 2 2 0 zinc-ribbon domain DUF2039 PF10217.4 EGG06969.1 - 3.1 7.8 13.9 0.53 10.3 4.8 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2039) LIM PF00412.17 EGG06969.1 - 4.3 7.4 11.0 14 5.7 0.1 3.4 3 1 0 3 3 3 0 LIM domain Actin PF00022.14 EGG06970.1 - 6e-121 403.5 0.0 8.1e-121 403.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGG06970.1 - 0.092 11.3 0.0 0.34 9.4 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein Histone PF00125.19 EGG06973.1 - 3.1e-21 75.2 0.0 3.8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGG06973.1 - 1.9e-06 27.8 0.0 2.3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EGG06973.1 - 0.00034 20.8 0.0 0.00043 20.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CAP_GLY PF01302.20 EGG06974.1 - 1.3e-25 88.8 0.2 2.4e-25 88.0 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EGG06974.1 - 1.5e-20 73.2 0.1 2.4e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EGG06974.1 - 4.6e-07 29.1 0.2 0.029 13.7 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family CRM1_C PF08767.6 EGG06975.1 - 9.9e-118 392.6 0.5 2.5e-116 388.0 0.0 2.7 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EGG06975.1 - 1.9e-39 134.9 6.8 2.5e-39 134.5 3.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EGG06975.1 - 3.6e-14 52.4 0.5 1.9e-13 50.0 0.2 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.3 EGG06975.1 - 0.019 14.8 0.0 0.19 11.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Nrap PF03813.9 EGG06976.1 - 2.1e-165 551.9 0.0 1.6e-123 413.2 0.0 3.0 1 1 1 2 2 2 2 Nrap protein RRM_3 PF08777.6 EGG06977.1 - 1.9e-05 24.4 0.0 0.00011 22.0 0.0 2.1 1 1 0 1 1 1 1 RNA binding motif Cap_synth_GfcB PF11102.3 EGG06977.1 - 0.022 14.2 0.5 0.034 13.7 0.3 1.3 1 0 0 1 1 1 0 Group 4 capsule polysaccharide formation lipoprotein gfcB PAGK PF15284.1 EGG06977.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Phage-encoded virulence factor Glyco_hydro_15 PF00723.16 EGG06978.1 - 5.4e-49 166.9 0.0 4e-47 160.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 RVP PF00077.15 EGG06980.1 - 0.0025 17.7 0.9 0.009 15.9 0.0 2.5 3 0 0 3 3 3 1 Retroviral aspartyl protease Asp_protease PF09668.5 EGG06980.1 - 0.0091 15.5 0.1 0.053 13.0 0.1 2.2 1 1 0 1 1 1 1 Aspartyl protease Syntaxin PF00804.20 EGG06980.1 - 0.017 15.2 8.4 1.9 8.7 4.1 2.7 1 1 1 2 2 2 0 Syntaxin DASH_Dad4 PF08650.5 EGG06980.1 - 0.027 14.3 6.9 2.6 8.0 0.2 3.7 3 0 0 3 3 3 0 DASH complex subunit Dad4 gag-asp_proteas PF13975.1 EGG06980.1 - 0.033 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Sec8_exocyst PF04048.9 EGG06980.1 - 0.24 11.0 7.7 0.05 13.2 0.7 2.4 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain FlxA PF14282.1 EGG06981.1 - 0.012 15.5 2.1 0.012 15.5 1.4 3.3 2 1 1 3 3 3 0 FlxA-like protein Seryl_tRNA_N PF02403.17 EGG06981.1 - 0.051 13.5 0.4 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 EGG06981.1 - 0.21 11.1 1.7 0.44 10.0 1.2 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF3573 PF12097.3 EGG06981.1 - 0.28 9.7 5.2 0.15 10.6 2.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) SnoaL_3 PF13474.1 EGG06988.1 - 0.00091 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EGG06988.1 - 0.0013 18.6 0.0 0.0023 17.8 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain EGF_alliinase PF04863.8 EGG06989.1 - 0.2 11.6 3.9 0.23 11.4 1.0 2.3 2 1 0 2 2 2 0 Alliinase EGF-like domain PQ-loop PF04193.9 EGG06990.1 - 1.2e-18 66.3 7.6 3.1e-15 55.4 0.3 3.1 3 0 0 3 3 3 2 PQ loop repeat MIP PF00230.15 EGG06992.1 - 3.9e-15 55.9 9.2 4.7e-11 42.5 4.0 3.2 1 1 1 2 2 2 2 Major intrinsic protein Transferase PF02458.10 EGG06992.1 - 0.18 10.1 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 Transferase family V-ATPase_G PF03179.10 EGG06993.1 - 6.4e-35 119.6 13.9 7.2e-35 119.4 9.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EGG06993.1 - 0.036 13.8 18.9 0.061 13.1 7.9 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) RRF PF01765.14 EGG06993.1 - 0.057 12.8 9.1 0.085 12.3 6.3 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Nop25 PF09805.4 EGG06993.1 - 0.081 12.9 11.4 0.1 12.6 7.9 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) 4HB_MCP_1 PF12729.2 EGG06993.1 - 0.089 12.1 4.7 0.051 12.9 1.0 1.8 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction Bacillus_HBL PF05791.6 EGG06993.1 - 0.093 12.0 2.5 0.11 11.8 1.8 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) XH PF03469.9 EGG06993.1 - 0.11 12.0 3.6 0.16 11.6 2.5 1.3 1 0 0 1 1 1 0 XH domain CENP-H PF05837.7 EGG06993.1 - 0.13 12.4 7.8 0.11 12.6 3.0 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ATP-synt_F6 PF05511.6 EGG06993.1 - 0.26 11.1 4.9 3.6 7.5 0.2 2.4 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Vfa1 PF08432.5 EGG06993.1 - 0.3 11.1 9.8 0.37 10.7 6.8 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MMR_HSR1_C PF08438.5 EGG06993.1 - 0.82 9.9 3.4 1.3 9.2 2.3 1.4 1 1 0 1 1 1 0 GTPase of unknown function C-terminal Paramyxo_ncap PF00973.14 EGG06993.1 - 1.5 7.4 5.0 1.5 7.4 3.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4375 PF14300.1 EGG06993.1 - 1.7 8.6 5.3 1.9 8.5 2.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) DUF3552 PF12072.3 EGG06993.1 - 2.1 7.5 16.3 4.7 6.3 11.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) vATP-synt_E PF01991.13 EGG06993.1 - 2.1 7.5 16.7 3.4 6.8 5.8 2.1 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit HrpE PF06188.7 EGG06993.1 - 2.6 7.7 5.5 4.5 6.9 2.5 1.8 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF4168 PF13767.1 EGG06993.1 - 5 7.8 9.5 0.82 10.3 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) DUF883 PF05957.8 EGG06993.1 - 6.7 7.1 7.2 12 6.3 3.4 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) RR_TM4-6 PF06459.7 EGG06994.1 - 0.3 10.9 1.6 0.45 10.3 1.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.7 EGG06994.1 - 3.8 5.3 11.3 5.8 4.7 7.8 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 EGG06994.1 - 7.2 4.8 13.2 13 4.0 9.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NUDIX PF00293.23 EGG06995.1 - 1.8e-10 40.5 0.2 2.3e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain HMG_box PF00505.14 EGG06997.1 - 0.00037 20.7 0.1 0.00087 19.5 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box CDP-OH_P_transf PF01066.16 EGG07002.1 - 6.7e-14 52.0 2.0 1.2e-13 51.1 1.4 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase MscS_TM PF12794.2 EGG07002.1 - 0.025 13.1 0.2 0.039 12.5 0.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 HD PF01966.17 EGG07003.1 - 4.7e-06 26.6 0.6 3e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 HD domain HD_4 PF13328.1 EGG07003.1 - 0.0018 17.9 0.2 0.0037 17.0 0.2 1.4 1 0 0 1 1 1 1 HD domain PX PF00787.19 EGG07004.1 - 4.5e-20 71.5 0.0 1e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 PX domain DUF3215 PF11503.3 EGG07004.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) Ribosomal_L16 PF00252.13 EGG07005.1 - 1.8e-32 111.8 0.1 2.2e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF2414 PF10309.4 EGG07006.1 - 1.8e-05 24.3 0.0 3.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) FoP_duplication PF13865.1 EGG07006.1 - 0.0021 18.4 2.0 0.0021 18.4 1.4 3.5 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Methyltransf_23 PF13489.1 EGG07007.1 - 7.7e-24 84.2 0.0 1.2e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG07007.1 - 7.4e-17 61.6 0.1 2.9e-16 59.7 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG07007.1 - 7.5e-17 61.3 0.1 2.1e-15 56.6 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG07007.1 - 6e-15 55.8 0.1 9e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG07007.1 - 1.5e-14 54.2 0.1 3.5e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG07007.1 - 1.8e-07 31.2 0.0 3.5e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGG07007.1 - 2.6e-06 26.7 0.0 6.2e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EGG07007.1 - 4.7e-06 26.8 0.1 1.4e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGG07007.1 - 1.7e-05 24.0 0.0 0.00031 19.8 0.0 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EGG07007.1 - 0.00011 21.0 0.1 0.00041 19.1 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.14 EGG07007.1 - 0.00018 21.5 0.0 0.00036 20.5 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.9 EGG07007.1 - 0.00027 20.1 0.0 0.00049 19.3 0.0 1.4 1 1 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 EGG07007.1 - 0.00047 19.3 0.0 0.0012 18.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGG07007.1 - 0.00062 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 EGG07007.1 - 0.0013 18.1 0.0 0.37 10.1 0.0 2.1 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EGG07007.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EGG07007.1 - 0.044 12.6 0.0 0.22 10.3 0.0 1.9 1 1 0 1 1 1 0 DREV methyltransferase TPMT PF05724.6 EGG07007.1 - 0.054 12.9 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.14 EGG07007.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Peptidase_C13 PF01650.13 EGG07008.1 - 1e-43 149.5 0.1 1.3e-43 149.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Ribosom_S12_S23 PF00164.20 EGG07009.1 - 1.4e-30 105.2 0.3 1.6e-30 105.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ABC_tran PF00005.22 EGG07012.1 - 6.8e-24 84.7 0.0 5.5e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EGG07012.1 - 2.5e-13 49.3 6.7 4.9e-13 48.4 4.6 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EGG07012.1 - 1.9e-12 47.7 4.4 0.0001 22.3 0.0 3.7 4 1 1 5 5 4 3 AAA domain SMC_N PF02463.14 EGG07012.1 - 2.9e-11 43.0 1.4 0.00091 18.5 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EGG07012.1 - 5.9e-06 25.5 0.5 0.54 9.2 0.0 3.3 3 1 0 3 3 3 3 AAA ATPase domain NACHT PF05729.7 EGG07012.1 - 0.0034 17.0 0.0 0.0072 15.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain SbcCD_C PF13558.1 EGG07012.1 - 0.0037 17.1 0.2 5.4 6.9 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EGG07012.1 - 0.01 15.9 0.0 0.031 14.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGG07012.1 - 0.013 16.3 0.0 0.23 12.2 0.0 2.7 2 2 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EGG07012.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EGG07012.1 - 0.024 14.8 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGG07012.1 - 0.034 14.1 0.0 0.092 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EGG07012.1 - 0.066 13.5 0.9 0.11 12.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EGG07012.1 - 0.097 12.3 0.0 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EGG07012.1 - 0.099 12.8 0.0 0.39 10.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase SRP54 PF00448.17 EGG07012.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF258 PF03193.11 EGG07012.1 - 0.13 11.3 1.1 0.62 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Glyco_hydro_17 PF00332.13 EGG07014.1 - 1.1e-06 27.8 0.9 5e-06 25.7 0.1 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 DUF1264 PF06884.6 EGG07017.1 - 1.2e-19 70.4 0.9 1.3e-19 70.3 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Mitochondr_Som1 PF11093.3 EGG07017.1 - 0.13 12.1 0.4 0.13 12.0 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial export protein Som1 DUF1264 PF06884.6 EGG07018.1 - 1.9e-15 56.7 0.1 3.3e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) AFT PF08731.6 EGG07020.1 - 0.0014 18.7 0.1 0.0014 18.7 0.1 3.4 4 0 0 4 4 4 1 Transcription factor AFT DDE_1 PF03184.14 EGG07023.1 - 0.0017 17.5 0.3 0.0024 17.0 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease IPP-2 PF04979.9 EGG07026.1 - 2.8e-11 43.8 9.3 2.2e-05 24.6 2.9 2.3 1 1 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) IPP-2 PF04979.9 EGG07027.1 - 6.1e-10 39.4 8.3 1.9e-08 34.5 5.8 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) UvsY PF11056.3 EGG07027.1 - 0.14 12.2 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY ABC_tran PF00005.22 EGG07028.1 - 2.5e-51 173.5 0.4 6.2e-29 101.0 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 EGG07028.1 - 9.1e-25 87.5 15.3 4.3e-21 75.5 1.8 4.0 3 1 0 3 3 3 2 ABC transporter transmembrane region T2SE PF00437.15 EGG07028.1 - 2.2e-09 36.5 0.3 0.00025 20.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 EGG07028.1 - 2.8e-09 36.3 1.2 9.5e-05 21.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EGG07028.1 - 3e-07 29.9 6.5 0.08 12.1 1.8 4.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 EGG07028.1 - 4.3e-07 29.9 0.2 0.0034 17.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_21 PF13304.1 EGG07028.1 - 5e-07 29.9 0.3 0.61 9.9 0.1 4.6 4 1 1 5 5 4 1 AAA domain AAA_16 PF13191.1 EGG07028.1 - 5.1e-07 29.8 0.4 0.018 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EGG07028.1 - 5.7e-07 30.3 2.5 0.052 14.3 0.0 4.3 5 0 0 5 5 2 2 AAA domain AAA_25 PF13481.1 EGG07028.1 - 7.6e-07 28.7 1.5 0.0035 16.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGG07028.1 - 7.8e-06 26.0 0.5 0.4 10.8 0.0 4.0 3 1 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 EGG07028.1 - 9.7e-06 25.1 0.1 0.075 12.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 EGG07028.1 - 2.4e-05 24.7 5.4 0.00037 20.8 0.1 2.6 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EGG07028.1 - 2.5e-05 23.8 0.2 0.095 12.1 0.0 2.6 3 0 0 3 3 2 2 AAA-like domain MobB PF03205.9 EGG07028.1 - 2.6e-05 23.9 1.0 0.056 13.1 0.1 3.4 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGG07028.1 - 2.8e-05 24.0 0.0 0.35 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EGG07028.1 - 7e-05 22.7 0.5 0.16 11.9 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase NACHT PF05729.7 EGG07028.1 - 0.00016 21.3 2.0 0.34 10.5 0.0 3.3 2 1 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 EGG07028.1 - 0.00063 20.0 0.9 0.59 10.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 EGG07028.1 - 0.00091 18.4 0.1 0.62 9.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 EGG07028.1 - 0.0015 18.2 0.8 0.064 13.0 0.1 3.1 3 0 0 3 3 2 1 Part of AAA domain TrwB_AAD_bind PF10412.4 EGG07028.1 - 0.0015 17.2 0.3 0.19 10.3 0.1 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 EGG07028.1 - 0.0023 17.5 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 EGG07028.1 - 0.0031 17.3 0.8 1 9.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.7 EGG07028.1 - 0.0035 16.4 0.5 3.3 6.7 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.17 EGG07028.1 - 0.0062 16.7 0.0 3.3 7.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 EGG07028.1 - 0.0066 16.0 0.2 6 6.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 EGG07028.1 - 0.012 15.2 3.3 1 9.1 0.0 3.9 5 0 0 5 5 3 0 AAA domain (dynein-related subfamily) Miro PF08477.8 EGG07028.1 - 0.013 16.0 1.9 6.2 7.3 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein IstB_IS21 PF01695.12 EGG07028.1 - 0.013 14.9 0.2 5 6.5 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein cobW PF02492.14 EGG07028.1 - 0.021 14.2 0.8 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 EGG07028.1 - 0.026 13.5 0.3 1.9 7.3 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.17 EGG07028.1 - 0.029 13.8 0.6 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain KaiC PF06745.8 EGG07028.1 - 0.036 13.1 0.2 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 KaiC NTPase_1 PF03266.10 EGG07028.1 - 0.049 13.3 3.8 2.7 7.6 0.1 2.9 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.17 EGG07028.1 - 0.056 12.2 0.2 1.2 7.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 EGG07028.1 - 0.071 13.3 2.0 13 6.0 0.0 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EGG07028.1 - 0.1 11.7 0.2 11 5.1 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein APS_kinase PF01583.15 EGG07028.1 - 0.12 12.0 0.6 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase ESAG1 PF03238.8 EGG07028.1 - 0.12 11.6 0.1 0.25 10.5 0.1 1.4 1 0 0 1 1 1 0 ESAG protein Arch_ATPase PF01637.13 EGG07028.1 - 0.14 11.7 0.2 3.9 7.1 0.0 2.8 3 0 0 3 3 2 0 Archaeal ATPase Herpes_Helicase PF02689.9 EGG07028.1 - 0.2 9.3 0.0 0.33 8.6 0.0 1.3 1 0 0 1 1 1 0 Helicase AAA_14 PF13173.1 EGG07028.1 - 0.21 11.5 0.2 8.5 6.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EGG07028.1 - 0.29 10.5 0.4 16 4.8 0.0 3.0 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EGG07028.1 - 0.33 10.5 0.8 6.8 6.2 0.1 2.5 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.11 EGG07028.1 - 3 6.8 4.2 25 3.8 0.1 3.1 3 0 0 3 3 3 0 AIG1 family Reo_sigmaC PF04582.7 EGG07029.1 - 0.075 12.1 0.0 0.08 12.1 0.0 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein rve PF00665.21 EGG07030.1 - 0.015 15.4 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain HEAT_2 PF13646.1 EGG07031.1 - 2.2e-05 24.6 0.1 3.6e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.17 EGG07031.1 - 0.0002 21.1 0.2 0.52 10.5 0.0 2.9 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 EGG07031.1 - 0.0093 16.4 0.7 1 9.9 0.1 2.4 2 1 0 2 2 2 2 HEAT-like repeat DUF3767 PF12597.3 EGG07032.1 - 3.7e-05 23.3 0.0 7.9e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3767) ATP-synt_C PF00137.16 EGG07033.1 - 4.3e-25 87.4 36.1 7.2e-14 51.4 8.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ATP-synt_J PF04911.7 EGG07033.1 - 2.8 7.4 4.6 9.6 5.7 0.5 2.6 2 0 0 2 2 2 0 ATP synthase j chain PADR1 PF08063.7 EGG07034.1 - 7.3 6.0 10.2 2.2 7.7 4.7 2.0 1 1 1 2 2 2 0 PADR1 (NUC008) domain LRR_2 PF07723.8 EGG07036.1 - 0.027 14.9 2.0 1.2 9.7 1.1 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_4 PF12799.2 EGG07036.1 - 0.43 10.2 8.9 5.5 6.7 0.1 4.6 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) ATP-synt_E PF05680.7 EGG07037.1 - 2.4 8.1 6.7 0.4 10.6 0.8 2.3 2 1 1 3 3 3 0 ATP synthase E chain PBP_sp32 PF07222.7 EGG07037.1 - 2.8 7.0 7.0 5.2 6.1 4.8 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 ATP-synt_E PF05680.7 EGG07038.1 - 2.4 8.1 6.7 0.4 10.6 0.8 2.3 2 1 1 3 3 3 0 ATP synthase E chain PBP_sp32 PF07222.7 EGG07038.1 - 2.8 7.0 7.0 5.2 6.1 4.8 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF2779 PF11074.3 EGG07039.1 - 0.13 12.3 0.2 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) COX6B PF02297.12 EGG07040.1 - 3.1e-17 62.3 9.3 4.1e-17 61.9 6.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EGG07040.1 - 0.12 11.8 0.8 0.26 10.7 0.6 1.6 1 0 0 1 1 1 0 APOBEC-like C-terminal domain VanZ PF04892.7 EGG07041.1 - 2.1e-10 40.6 1.3 9.5e-10 38.5 0.9 2.0 1 1 0 1 1 1 1 VanZ like family zf-UBP PF02148.14 EGG07044.1 - 4.9 7.3 7.0 25 5.0 4.9 2.2 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Dioxygenase_C PF00775.16 EGG07047.1 - 5.9e-10 38.7 0.0 6.6e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 Dioxygenase Squash PF00299.13 EGG07048.1 - 0.01 15.6 0.8 0.03 14.1 0.5 1.8 1 0 0 1 1 1 0 Squash family serine protease inhibitor FOLN PF09289.5 EGG07048.1 - 0.029 14.2 0.4 0.052 13.3 0.3 1.4 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Pkinase PF00069.20 EGG07050.1 - 4.1e-65 219.5 0.0 1e-64 218.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG07050.1 - 2.2e-35 122.0 0.0 3.7e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EGG07050.1 - 1.5e-24 85.4 8.3 4.1e-13 48.8 2.8 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EGG07050.1 - 9.2e-22 76.5 23.0 1.5e-11 43.8 6.1 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EGG07050.1 - 3.6e-10 40.1 0.1 3.6e-10 40.1 0.1 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.25 EGG07050.1 - 6.3e-06 25.9 0.1 1.3e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.1 EGG07050.1 - 0.015 14.3 0.0 0.033 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like C1_3 PF07649.7 EGG07050.1 - 0.044 13.8 10.6 2.1 8.4 4.9 2.5 2 0 0 2 2 2 0 C1-like domain DNA_pol_E_B PF04042.11 EGG07051.1 - 2.2e-29 102.2 0.2 3.3e-29 101.6 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 EGG07051.1 - 1.1e-23 84.0 0.8 1.9e-23 83.2 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal SnoaL_2 PF12680.2 EGG07052.1 - 0.00094 19.5 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain HA2 PF04408.18 EGG07054.1 - 1.3e-17 63.6 0.0 4.1e-17 62.0 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGG07054.1 - 1e-16 60.7 0.0 3.4e-16 59.0 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGG07054.1 - 3.8e-13 49.0 0.0 1.1e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGG07054.1 - 4.2e-07 30.1 0.0 1.3e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EGG07054.1 - 2.5e-06 27.0 0.1 6.7e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGG07054.1 - 0.00027 20.8 0.3 0.2 11.4 0.0 3.2 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit T2SE PF00437.15 EGG07054.1 - 0.0025 16.7 0.0 0.0052 15.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 EGG07054.1 - 0.0057 17.0 0.1 0.0057 17.0 0.1 3.5 3 2 0 3 3 2 1 AAA domain AAA_30 PF13604.1 EGG07054.1 - 0.0067 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGG07054.1 - 0.013 14.6 0.1 0.056 12.5 0.0 2.0 2 0 0 2 2 2 0 KaiC FtsK_SpoIIIE PF01580.13 EGG07054.1 - 0.024 14.1 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.1 EGG07054.1 - 0.093 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EGG07054.1 - 0.13 11.7 0.0 0.64 9.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain DNA_methylase PF00145.12 EGG07057.1 - 2.7e-40 138.5 0.0 3.9e-39 134.7 0.0 2.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Glyco_hydro_7 PF00840.15 EGG07059.1 - 6.9e-140 466.2 2.7 8e-140 466.0 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 ecTbetaR2 PF08917.5 EGG07059.1 - 0.0037 17.0 1.6 0.009 15.7 1.1 1.6 1 0 0 1 1 1 1 Transforming growth factor beta receptor 2 ectodomain Pkinase PF00069.20 EGG07064.1 - 2.1e-67 226.9 0.0 2.5e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG07064.1 - 6.1e-26 91.0 0.0 7.1e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG07064.1 - 8.6e-06 24.9 0.2 0.012 14.5 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 EGG07064.1 - 0.00031 20.1 0.1 0.00048 19.5 0.1 1.2 1 0 0 1 1 1 1 RIO1 family TFIID-18kDa PF02269.11 EGG07066.1 - 2.4e-14 52.8 0.3 8.2e-12 44.7 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit CPSase_L_D2 PF02786.12 EGG07067.1 - 2.6e-78 262.1 0.5 4.4e-78 261.4 0.3 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EGG07067.1 - 3.7e-69 232.0 0.0 7e-69 231.1 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EGG07067.1 - 7.9e-37 125.7 0.2 2.3e-36 124.2 0.0 2.0 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGG07067.1 - 5.8e-30 103.4 0.0 1.5e-29 102.0 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EGG07067.1 - 5.6e-28 98.1 0.0 1.4e-27 96.9 0.0 1.7 2 0 0 2 2 1 1 HMGL-like ATP-grasp_4 PF13535.1 EGG07067.1 - 1.1e-19 70.8 0.3 2.1e-19 69.9 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGG07067.1 - 4.6e-17 61.7 0.1 3.7e-16 58.7 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EGG07067.1 - 1.2e-16 60.0 3.7 4.9e-16 58.1 2.4 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EGG07067.1 - 1.6e-12 47.2 0.0 2.9e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EGG07067.1 - 1e-10 41.1 3.4 2.7e-05 23.7 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 EGG07067.1 - 9.4e-07 28.3 0.1 2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGG07067.1 - 2.4e-05 24.2 0.0 5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EGG07067.1 - 4.3e-05 23.7 0.3 0.51 10.6 0.0 3.0 2 0 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 EGG07067.1 - 0.0011 18.3 1.0 0.053 12.8 0.0 2.4 2 0 0 2 2 2 1 HlyD family secretion protein NQRA PF05896.6 EGG07067.1 - 0.0012 18.1 0.2 0.0023 17.1 0.1 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RimK PF08443.6 EGG07067.1 - 0.0012 18.3 0.0 0.0039 16.6 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EGG07067.1 - 0.0014 18.2 0.1 0.0034 16.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.14 EGG07067.1 - 0.018 14.7 0.6 0.072 12.7 0.2 2.1 1 1 1 2 2 2 0 Glycine cleavage H-protein HlyD_2 PF12700.2 EGG07067.1 - 0.22 10.6 0.1 5.4 6.0 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein LCM PF04072.9 EGG07068.1 - 6.1e-17 61.7 0.0 9.3e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Methyltransf_23 PF13489.1 EGG07068.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SRP54 PF00448.17 EGG07070.1 - 1.5e-47 161.6 0.1 2.7e-47 160.7 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EGG07070.1 - 2.6e-31 109.0 4.3 4.1e-30 105.1 3.0 2.0 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal ArgK PF03308.11 EGG07070.1 - 4.4e-08 32.2 0.0 8.1e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EGG07070.1 - 7.7e-08 31.9 0.0 1.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 EGG07070.1 - 1.9e-05 24.6 0.1 0.0001 22.3 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.1 EGG07070.1 - 0.00036 20.6 0.0 0.0061 16.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGG07070.1 - 0.0047 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EGG07070.1 - 0.0061 15.6 0.7 0.11 11.4 0.0 2.7 2 1 1 3 3 3 1 Anion-transporting ATPase MobB PF03205.9 EGG07070.1 - 0.012 15.2 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGG07070.1 - 0.014 15.4 0.7 0.061 13.3 0.0 2.4 2 1 1 3 3 3 0 AAA ATPase domain SMC_N PF02463.14 EGG07070.1 - 0.023 13.9 0.5 4.4 6.4 0.2 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 EGG07070.1 - 0.054 13.0 2.3 0.096 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.13 EGG07070.1 - 0.072 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NPV_P10 PF05531.7 EGG07071.1 - 0.0024 18.0 1.4 0.0024 18.0 1.0 2.3 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein LPP PF04728.8 EGG07071.1 - 0.011 15.4 1.8 0.053 13.3 0.7 2.4 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF4254 PF14063.1 EGG07071.1 - 0.016 14.7 3.3 0.032 13.8 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Fzo_mitofusin PF04799.8 EGG07071.1 - 0.12 11.7 2.0 0.28 10.5 1.4 1.6 1 0 0 1 1 1 0 fzo-like conserved region FlaC_arch PF05377.6 EGG07071.1 - 0.48 10.3 4.5 5.9 6.8 0.5 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) SlyX PF04102.7 EGG07071.1 - 8.9 6.7 8.6 6.2 7.2 0.4 2.7 1 1 1 2 2 2 0 SlyX CCDC-167 PF15188.1 EGG07072.1 - 0.0081 16.0 2.8 0.012 15.5 1.7 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 DUF2605 PF10792.4 EGG07072.1 - 0.011 15.4 0.5 0.055 13.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) DUF4559 PF15112.1 EGG07072.1 - 0.026 13.7 4.4 0.034 13.3 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Tn7_Tnp_TnsA_C PF08721.6 EGG07072.1 - 0.11 12.4 1.7 22 5.1 0.1 3.4 4 0 0 4 4 4 0 TnsA endonuclease C terminal APG6 PF04111.7 EGG07072.1 - 0.13 11.3 4.2 0.15 11.0 2.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spore_III_AB PF09548.5 EGG07072.1 - 0.15 11.8 1.5 0.21 11.3 1.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) CENP-H PF05837.7 EGG07072.1 - 0.17 12.0 1.8 0.27 11.4 1.3 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Ice_nucleation PF00818.12 EGG07073.1 - 0.57 9.6 1.8 1.1 8.7 1.3 1.4 1 0 0 1 1 1 0 Ice nucleation protein repeat NAM-associated PF14303.1 EGG07075.1 - 7.8e-08 32.7 0.0 1.3e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain BLOC1_2 PF10046.4 EGG07075.1 - 0.058 13.5 1.0 0.28 11.3 0.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WASH-7_N PF14745.1 EGG07075.1 - 0.087 10.9 0.0 0.12 10.5 0.0 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal SMC_Nse1 PF07574.8 EGG07078.1 - 5.3e-18 65.3 0.4 2.5e-15 56.6 0.0 2.6 2 1 0 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EGG07078.1 - 4.7e-05 23.2 10.1 4.7e-05 23.2 7.0 1.6 2 0 0 2 2 2 1 RING-like domain Rtf2 PF04641.7 EGG07078.1 - 0.031 13.4 6.5 0.045 12.9 4.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3381 PF11861.3 EGG07078.1 - 0.23 10.9 9.9 0.36 10.3 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PRP38_assoc PF12871.2 EGG07078.1 - 0.27 11.7 15.5 0.47 11.0 10.7 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term YqfQ PF14181.1 EGG07078.1 - 6 6.8 12.2 10 6.1 8.4 1.2 1 0 0 1 1 1 0 YqfQ-like protein PPR PF01535.15 EGG07079.1 - 8.8e-24 81.7 5.0 0.14 12.2 0.1 10.4 9 0 0 9 9 9 7 PPR repeat PPR_3 PF13812.1 EGG07079.1 - 1.1e-22 78.3 8.0 0.017 15.3 0.0 11.6 13 0 0 13 13 13 6 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGG07079.1 - 1.8e-22 79.0 0.0 2.7e-06 27.2 0.1 9.2 8 2 2 10 10 10 4 PPR repeat family PPR_1 PF12854.2 EGG07079.1 - 5.3e-07 29.0 0.8 2.3 7.7 0.0 6.5 7 0 0 7 7 7 2 PPR repeat TPR_19 PF14559.1 EGG07079.1 - 0.0025 18.1 4.8 0.73 10.2 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EGG07079.1 - 0.0055 16.8 0.0 11 6.2 0.0 5.2 6 0 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 SPOB_a PF14689.1 EGG07079.1 - 0.029 13.9 0.1 0.41 10.2 0.0 3.0 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain Ndc1_Nup PF09531.5 EGG07082.1 - 0.77 8.1 2.1 1.6 7.0 1.5 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C3H1 PF10650.4 EGG07083.1 - 0.037 13.4 2.3 0.23 11.0 0.2 2.7 2 0 0 2 2 2 0 Putative zinc-finger domain zf-C3H1 PF10650.4 EGG07084.1 - 0.037 13.4 2.3 0.23 11.0 0.2 2.7 2 0 0 2 2 2 0 Putative zinc-finger domain TFIIF_alpha PF05793.7 EGG07088.1 - 1.2 7.4 7.1 1.6 7.0 4.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GFA PF04828.9 EGG07089.1 - 7.6e-23 80.2 0.1 1.1e-22 79.8 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EGG07089.1 - 0.052 13.2 4.8 0.22 11.2 0.0 2.5 2 0 0 2 2 2 0 Nudix N-terminal DUF1990 PF09348.5 EGG07089.1 - 0.072 12.7 0.0 0.092 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) Elf1 PF05129.8 EGG07089.1 - 0.11 12.2 0.6 2 8.1 0.2 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-B_box PF00643.19 EGG07089.1 - 0.11 12.4 0.9 1.7 8.6 0.0 2.9 3 0 0 3 3 3 0 B-box zinc finger Yippee-Mis18 PF03226.9 EGG07089.1 - 0.11 12.5 0.1 0.31 11.0 0.1 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Lar_restr_allev PF14354.1 EGG07089.1 - 0.46 10.8 2.5 7.6 6.9 1.8 2.2 1 1 0 1 1 1 0 Restriction alleviation protein Lar DZR PF12773.2 EGG07089.1 - 0.77 9.6 4.5 3.5 7.5 3.2 2.2 1 1 0 1 1 1 0 Double zinc ribbon FAD_binding_4 PF01565.18 EGG07090.1 - 6.4e-20 71.0 2.4 6.4e-20 71.0 1.7 1.8 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.7 EGG07090.1 - 3e-09 36.6 0.1 5.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.14 EGG07090.1 - 0.04 13.2 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain PBP1_TM PF14812.1 EGG07092.1 - 4.9 7.5 8.8 17 5.7 0.9 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Lyase_8_C PF02884.12 EGG07093.1 - 0.066 13.2 0.1 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain SMK-1 PF04802.10 EGG07094.1 - 1.7e-62 210.3 0.1 3.7e-62 209.3 0.1 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Nucleo_P87 PF07267.6 EGG07094.1 - 3.9 6.0 7.2 0.1 11.3 0.4 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.1 EGG07094.1 - 5.1 7.4 7.2 28 5.1 0.3 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Complex1_LYR_1 PF13232.1 EGG07095.1 - 0.00032 20.8 0.1 0.00041 20.4 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Phage_T4_gp19 PF06841.7 EGG07095.1 - 0.0093 15.5 0.1 0.011 15.3 0.1 1.1 1 0 0 1 1 1 1 T4-like virus tail tube protein gp19 Complex1_LYR PF05347.10 EGG07095.1 - 0.16 11.7 1.0 0.28 10.9 0.6 1.5 1 1 0 1 1 1 0 Complex 1 protein (LYR family) 2OG-FeII_Oxy_2 PF13532.1 EGG07097.1 - 0.018 14.8 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Gln-synt_C PF00120.19 EGG07098.1 - 1.9e-56 191.1 0.0 2.5e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain ADH_zinc_N PF00107.21 EGG07099.1 - 6.5e-14 51.6 0.0 1.3e-13 50.6 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EGG07099.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding DUF1624 PF07786.7 EGG07100.1 - 1e-06 28.2 0.1 0.00014 21.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1624) Ferritin_2 PF13668.1 EGG07101.1 - 1.8e-48 163.9 2.7 2.5e-48 163.5 1.9 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.1 EGG07102.1 - 7.3e-48 162.0 0.7 9.9e-48 161.5 0.5 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF872 PF05915.7 EGG07106.1 - 0.86 9.4 3.6 1.6 8.5 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) AAA_31 PF13614.1 EGG07107.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RPAP1_C PF08620.5 EGG07109.1 - 0.077 12.8 0.4 0.19 11.5 0.1 1.8 2 0 0 2 2 2 0 RPAP1-like, C-terminal MRP-L46 PF11788.3 EGG07111.1 - 3.4e-13 50.2 0.7 5.9e-13 49.4 0.5 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EGG07111.1 - 6.5e-10 38.7 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain ArsR PF09824.4 EGG07111.1 - 0.11 11.8 0.2 0.56 9.5 0.0 2.1 2 0 0 2 2 2 0 ArsR transcriptional regulator AhpC-TSA_2 PF13911.1 EGG07113.1 - 4.4e-12 45.9 0.0 8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGG07113.1 - 0.0001 21.9 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Abhydrolase_2 PF02230.11 EGG07115.1 - 3.4e-10 39.7 0.0 6.4e-09 35.5 0.2 2.5 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_2 PF02230.11 EGG07116.1 - 8.2e-09 35.2 0.0 4.2e-08 32.8 0.0 1.9 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Ribosomal_S6 PF01250.12 EGG07117.1 - 6.1e-11 42.0 0.0 8.1e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 PMT PF02366.13 EGG07118.1 - 2.8e-72 243.0 18.4 2.8e-72 243.0 12.8 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGG07118.1 - 2.9e-30 105.2 0.4 3.8e-30 104.8 0.2 1.2 1 0 0 1 1 1 1 MIR domain PCI PF01399.22 EGG07119.1 - 4.4e-08 33.3 0.5 1.6e-07 31.5 0.0 2.2 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EGG07119.1 - 9.5e-07 28.6 0.5 1.9e-06 27.6 0.1 1.7 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 DUF676 PF05057.9 EGG07125.1 - 0.0017 17.6 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGG07125.1 - 0.0022 17.5 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein LIP PF03583.9 EGG07125.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase ATP-synt PF00231.14 EGG07126.1 - 1.9e-65 221.0 5.6 2.2e-65 220.8 3.9 1.0 1 0 0 1 1 1 1 ATP synthase PXA PF02194.10 EGG07126.1 - 0.05 13.1 0.1 2 7.9 0.0 2.1 2 0 0 2 2 2 0 PXA domain Peptidase_S8 PF00082.17 EGG07127.1 - 1.4e-43 149.1 0.8 2.1e-43 148.5 0.6 1.3 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EGG07127.1 - 3.3e-08 33.1 0.0 9.9e-08 31.6 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 EGG07127.1 - 7e-05 23.2 0.0 0.0002 21.7 0.0 1.8 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) MutS_I PF01624.15 EGG07128.1 - 1.8e-13 50.4 0.0 2e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 MutS domain I MutS_V PF00488.16 EGG07129.1 - 1.6e-42 145.5 0.0 2.4e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGG07129.1 - 0.0028 17.4 0.2 0.0047 16.7 0.1 1.3 1 0 0 1 1 1 1 MutS domain III DUF964 PF06133.6 EGG07129.1 - 0.061 13.3 0.2 0.095 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF964) AAA_29 PF13555.1 EGG07129.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EGG07129.1 - 0.072 12.9 0.0 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Spc24 PF08286.6 EGG07130.1 - 2.2e-05 24.1 1.1 0.0017 18.0 0.0 2.3 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 APG6 PF04111.7 EGG07130.1 - 0.0094 15.0 6.9 0.013 14.5 4.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF2968 PF11180.3 EGG07130.1 - 0.018 14.4 5.5 0.025 13.9 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spc7 PF08317.6 EGG07130.1 - 0.021 13.5 7.2 0.028 13.1 5.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 EGG07130.1 - 0.023 13.6 4.7 0.03 13.2 3.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF869 PF05911.6 EGG07130.1 - 0.024 12.8 5.0 0.03 12.5 3.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Fib_alpha PF08702.5 EGG07130.1 - 0.036 14.1 4.7 0.054 13.6 3.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1423 PF07227.6 EGG07130.1 - 0.074 11.7 2.5 0.09 11.4 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DUF3340 PF11818.3 EGG07130.1 - 0.11 12.4 5.6 0.16 11.8 3.9 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF4559 PF15112.1 EGG07130.1 - 0.17 11.0 4.8 0.21 10.7 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) TBPIP PF07106.8 EGG07130.1 - 0.47 9.9 7.1 0.98 8.9 4.8 1.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EGG07130.1 - 0.49 10.1 10.8 2.5 7.8 6.6 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 EGG07130.1 - 1.2 9.0 12.7 2.1 8.2 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) FlgN PF05130.7 EGG07130.1 - 1.6 8.9 7.6 3.1 8.0 5.0 1.6 1 1 1 2 2 2 0 FlgN protein DivIC PF04977.10 EGG07130.1 - 2.7 7.5 8.7 9 5.8 0.3 2.4 1 1 1 2 2 2 0 Septum formation initiator YlqD PF11068.3 EGG07130.1 - 2.9 7.9 7.4 2.1 8.4 1.7 2.2 1 1 0 2 2 2 0 YlqD protein Glycos_trans_3N PF02885.12 EGG07134.1 - 0.075 12.6 0.1 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain DUF3129 PF11327.3 EGG07136.1 - 3.3e-18 66.1 0.8 5e-18 65.5 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Ribosomal_L34 PF00468.12 EGG07138.1 - 2.5e-20 71.8 8.2 3e-20 71.5 5.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L34 SSP160 PF06933.6 EGG07139.1 - 0.62 7.9 8.5 0.68 7.8 5.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF515 PF04415.7 EGG07139.1 - 0.64 8.1 8.7 0.75 7.9 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Herpes_capsid PF06112.6 EGG07139.1 - 2.2 8.3 8.9 2.2 8.3 6.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Brix PF04427.13 EGG07142.1 - 9.5e-44 149.3 5.1 3.5e-30 105.0 0.6 2.1 1 1 1 2 2 2 2 Brix domain eIF-5_eIF-2B PF01873.12 EGG07143.1 - 2.6e-43 146.6 0.0 3.3e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EGG07143.1 - 0.00021 20.5 0.3 0.00032 19.9 0.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Lar_restr_allev PF14354.1 EGG07143.1 - 0.0067 16.7 0.2 0.011 15.9 0.1 1.4 1 0 0 1 1 1 1 Restriction alleviation protein Lar IF2_N PF04760.10 EGG07143.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region zf-HYPF PF07503.7 EGG07143.1 - 0.077 12.4 0.1 11 5.4 0.0 2.5 2 0 0 2 2 2 0 HypF finger zinc_ribbon_4 PF13717.1 EGG07143.1 - 0.34 10.6 2.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGG07143.1 - 0.36 10.4 2.2 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Arc_trans_TRASH PF08394.5 EGG07143.1 - 0.41 10.8 7.3 0.81 9.8 0.1 2.4 1 1 1 2 2 2 0 Archaeal TRASH domain FrhB_FdhB_C PF04432.8 EGG07144.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus P34-Arc PF04045.9 EGG07146.1 - 3.9e-99 330.8 0.0 4.8e-99 330.5 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Late_protein_L1 PF00500.13 EGG07148.1 - 0.0012 17.4 0.0 0.0012 17.4 0.0 1.0 1 0 0 1 1 1 1 L1 (late) protein ATP-synt_J PF04911.7 EGG07152.1 - 2.6e-17 62.0 0.6 3.1e-17 61.7 0.4 1.1 1 0 0 1 1 1 1 ATP synthase j chain zf-RING_2 PF13639.1 EGG07153.1 - 7.1e-11 41.7 6.7 1.3e-10 40.9 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGG07153.1 - 2.9e-07 30.4 5.1 5.5e-07 29.5 3.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGG07153.1 - 7.2e-06 25.9 6.0 1.3e-05 25.1 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG07153.1 - 1.2e-05 24.8 2.5 2e-05 24.1 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG07153.1 - 0.0027 17.3 5.6 0.0056 16.3 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EGG07153.1 - 0.028 14.3 5.9 0.19 11.7 4.1 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EGG07153.1 - 0.03 14.3 5.1 0.056 13.5 3.5 1.5 1 0 0 1 1 1 0 RING-variant domain zf-P11 PF03854.9 EGG07153.1 - 0.033 13.6 0.5 0.033 13.6 0.4 2.3 2 1 0 2 2 2 0 P-11 zinc finger zf-RING_5 PF14634.1 EGG07153.1 - 0.064 13.0 5.7 0.12 12.1 3.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 EGG07153.1 - 0.16 11.7 4.0 0.41 10.5 2.7 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger YqeY PF09424.5 EGG07154.1 - 0.024 14.4 7.6 2.4 8.0 0.2 3.6 2 2 1 3 3 3 0 Yqey-like protein DUF2874 PF11396.3 EGG07154.1 - 0.2 11.6 1.6 18 5.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2874) LTXXQ PF07813.7 EGG07154.1 - 1.5 9.3 10.4 1.1 9.7 0.6 3.0 3 0 0 3 3 3 0 LTXXQ motif family protein TipAS PF07739.8 EGG07154.1 - 5.8 7.2 10.2 14 5.9 0.3 3.2 1 1 1 3 3 3 0 TipAS antibiotic-recognition domain TFIIB PF00382.14 EGG07155.1 - 1.2e-43 146.7 1.0 3.5e-22 77.9 0.2 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGG07155.1 - 4.2e-14 51.5 1.1 6.7e-14 50.9 0.8 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.15 EGG07155.1 - 0.00026 20.5 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain GerE PF00196.14 EGG07155.1 - 0.011 15.0 0.0 0.09 12.1 0.0 2.4 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.7 EGG07155.1 - 0.03 13.7 0.0 0.067 12.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Cyclin_N PF00134.18 EGG07155.1 - 0.034 13.7 0.1 0.064 12.8 0.1 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain HTH_38 PF13936.1 EGG07155.1 - 0.13 11.7 1.8 13 5.4 0.0 3.4 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_23 PF13384.1 EGG07155.1 - 0.14 11.8 0.6 1.6 8.4 0.0 2.9 4 0 0 4 4 4 0 Homeodomain-like domain zf-ribbon_3 PF13248.1 EGG07155.1 - 0.77 9.0 3.2 1.8 7.8 0.3 2.5 3 0 0 3 3 3 0 zinc-ribbon domain CorA PF01544.13 EGG07156.1 - 1.1e-05 24.6 2.8 1.8e-05 23.9 1.9 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ndc80_HEC PF03801.8 EGG07158.1 - 1.2e-36 125.5 0.0 1.2e-36 125.5 0.0 2.5 2 0 0 2 2 2 1 HEC/Ndc80p family CDC45 PF02724.9 EGG07159.1 - 0.004 15.2 8.2 0.0044 15.1 5.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Cas_Csn2 PF09711.5 EGG07159.1 - 0.081 12.5 0.4 0.11 12.1 0.3 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) NOA36 PF06524.7 EGG07159.1 - 0.17 11.1 4.6 0.24 10.6 3.2 1.3 1 0 0 1 1 1 0 NOA36 protein SRA1 PF07304.6 EGG07159.1 - 0.18 11.4 0.0 0.18 11.4 0.0 2.5 2 1 1 3 3 3 0 Steroid receptor RNA activator (SRA1) Macoilin PF09726.4 EGG07159.1 - 1.9 6.6 10.1 2.2 6.4 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Sigma70_ner PF04546.8 EGG07159.1 - 3.4 7.2 10.4 5 6.6 7.2 1.3 1 1 0 1 1 1 0 Sigma-70, non-essential region RR_TM4-6 PF06459.7 EGG07159.1 - 6 6.6 8.2 8 6.2 5.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EGG07159.1 - 9.6 5.5 13.0 13 5.1 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RGS PF00615.14 EGG07161.1 - 1e-29 103.0 0.0 1.9e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EGG07161.1 - 3.1e-12 46.0 0.0 1.8e-06 27.6 0.0 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) L27 PF02828.11 EGG07161.1 - 0.11 12.1 0.7 5.3 6.8 0.1 3.4 3 0 0 3 3 3 0 L27 domain NAC PF01849.13 EGG07162.1 - 9.1e-21 73.1 0.7 1.5e-20 72.4 0.5 1.3 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 EGG07162.1 - 0.00013 21.6 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EGG07162.1 - 0.028 13.9 0.0 0.077 12.5 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain Nop PF01798.13 EGG07165.1 - 1.5e-55 186.6 1.6 2.7e-55 185.7 1.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGG07165.1 - 9e-28 95.8 0.3 1.7e-27 94.9 0.2 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGG07165.1 - 5e-17 61.8 0.3 5e-17 61.8 0.2 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF948 PF06103.6 EGG07168.1 - 0.022 14.6 0.3 0.043 13.6 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) 2OG-FeII_Oxy PF03171.15 EGG07170.1 - 6.1e-11 42.4 0.0 1.1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGG07170.1 - 4.5e-06 27.1 0.0 7.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal RNA_Me_trans PF04252.8 EGG07171.1 - 1.3e-38 132.3 0.0 2.1e-33 115.3 0.0 2.1 2 0 0 2 2 2 2 Predicted SAM-dependent RNA methyltransferase Peptidase_S8 PF00082.17 EGG07172.1 - 2.9e-45 154.6 8.1 1.5e-43 148.9 5.6 2.2 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EGG07172.1 - 4.9e-10 39.7 0.3 9e-10 38.9 0.2 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EGG07172.1 - 0.00012 21.7 0.0 0.00037 20.1 0.0 1.8 1 0 0 1 1 1 1 PA domain Ada3 PF10198.4 EGG07173.1 - 7.9e-07 28.8 0.0 8.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Pro-kuma_activ PF09286.6 EGG07175.1 - 8e-36 123.2 0.2 2.1e-35 121.8 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGG07175.1 - 2.9e-09 36.4 0.3 5.9e-09 35.4 0.2 1.4 1 0 0 1 1 1 1 Subtilase family zf-RING_2 PF13639.1 EGG07178.1 - 6.4e-09 35.4 6.3 1.2e-08 34.5 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGG07178.1 - 1.2e-08 34.4 4.6 2.8e-08 33.2 3.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG07178.1 - 1.9e-07 30.6 4.7 4.4e-07 29.4 3.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG07178.1 - 2.3e-07 30.7 7.2 4e-06 26.7 5.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGG07178.1 - 1.2e-05 25.3 5.0 1.9e-05 24.6 3.5 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGG07178.1 - 0.0078 15.9 8.8 0.018 14.7 6.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGG07178.1 - 0.45 10.4 7.0 0.36 10.7 2.8 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 EGG07178.1 - 0.51 9.8 5.3 0.46 9.9 1.3 2.2 2 0 0 2 2 2 0 P-11 zinc finger DZR PF12773.2 EGG07178.1 - 3.2 7.6 5.7 4 7.3 1.0 2.1 1 1 1 2 2 2 0 Double zinc ribbon Brix PF04427.13 EGG07179.1 - 0.042 13.5 0.0 0.05 13.2 0.0 1.0 1 0 0 1 1 1 0 Brix domain PGM_PMM_I PF02878.11 EGG07180.1 - 2e-35 121.2 0.4 2.5e-34 117.7 0.1 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I ADH_zinc_N PF00107.21 EGG07180.1 - 8.6e-25 86.7 0.0 2.1e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PGM_PMM_II PF02879.11 EGG07180.1 - 3.4e-16 59.4 0.0 1.2e-14 54.5 0.0 3.0 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ADH_N PF08240.7 EGG07180.1 - 5.2e-14 51.9 0.0 1.1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PGM_PMM_III PF02880.11 EGG07180.1 - 3.1e-13 49.7 0.1 1e-12 48.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ADH_zinc_N_2 PF13602.1 EGG07180.1 - 1.3e-08 35.7 0.0 3.6e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Gar1 PF04410.9 EGG07181.1 - 2.5e-37 127.7 0.0 2.5e-37 127.7 0.0 2.1 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region HA2 PF04408.18 EGG07182.1 - 5.7e-26 90.5 1.9 3e-25 88.2 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGG07182.1 - 4e-25 87.8 0.0 1.2e-24 86.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGG07182.1 - 2e-14 53.1 0.0 5.7e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGG07182.1 - 0.0038 16.7 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Glyco_hydro_16 PF00722.16 EGG07183.1 - 1.5e-30 105.8 0.1 1.9e-30 105.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Cactin_mid PF10312.4 EGG07184.1 - 1.3e-56 190.8 10.0 3.9e-56 189.3 6.9 1.9 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EGG07184.1 - 9.4e-56 186.7 7.0 1.8e-55 185.8 4.9 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SBDS PF01172.13 EGG07185.1 - 2e-16 59.5 0.0 2.6e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Peptidase_S10 PF00450.17 EGG07187.1 - 9.2e-96 321.5 0.0 1.1e-95 321.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Oxidored_q1 PF00361.15 EGG07191.1 - 1.3e-06 27.9 0.4 2e-06 27.2 0.3 1.3 1 0 0 1 1 1 1 NADH-Ubiquinone/plastoquinone (complex I), various chains MFS_1 PF07690.11 EGG07192.1 - 1.9e-26 92.6 24.9 1.9e-26 92.6 17.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily 7TM_GPCR_Srbc PF10316.4 EGG07192.1 - 0.052 12.8 12.5 0.046 12.9 0.6 2.6 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc zf-rbx1 PF12678.2 EGG07194.1 - 3.8e-31 107.0 17.5 1.8e-22 79.1 5.1 2.1 1 1 1 2 2 2 2 RING-H2 zinc finger zf-Apc11 PF12861.2 EGG07194.1 - 1.5e-14 53.6 10.3 1.9e-10 40.4 1.9 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EGG07194.1 - 4.9e-08 32.6 8.9 1.6e-07 31.0 4.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGG07194.1 - 0.0017 18.3 9.3 0.029 14.3 6.0 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG07194.1 - 0.0019 17.7 8.3 0.0019 17.7 5.8 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG07194.1 - 0.0046 16.6 5.0 0.0046 16.6 3.5 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4001 PF13165.1 EGG07194.1 - 0.071 12.7 1.2 0.13 11.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4001) zf-RING_5 PF14634.1 EGG07194.1 - 0.24 11.1 11.8 0.12 12.0 4.9 2.5 2 1 0 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 EGG07194.1 - 0.27 11.2 8.0 0.23 11.4 3.9 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 EGG07194.1 - 0.7 9.9 8.3 0.98 9.4 5.7 1.4 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 EGG07194.1 - 0.72 9.6 5.3 0.18 11.5 1.2 1.9 2 1 0 2 2 2 0 RING-type zinc-finger PHD PF00628.24 EGG07194.1 - 2.9 7.6 9.3 1.6 8.4 3.5 2.3 2 0 0 2 2 2 0 PHD-finger DUF2205 PF10224.4 EGG07195.1 - 0.0044 16.5 0.4 0.025 14.1 0.2 2.4 1 1 1 2 2 2 1 Predicted coiled-coil protein (DUF2205) TACC PF05010.9 EGG07195.1 - 0.026 14.2 3.5 0.028 14.1 0.6 2.2 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Pepsin-I3 PF06394.8 EGG07195.1 - 0.12 12.0 0.1 0.37 10.4 0.1 1.8 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Scm3 PF10384.4 EGG07195.1 - 0.14 11.6 0.9 1.7 8.1 0.0 2.7 3 0 0 3 3 3 0 Centromere protein Scm3 Rotamase_3 PF13616.1 EGG07196.1 - 3.7e-13 49.7 0.0 5e-13 49.3 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EGG07196.1 - 3.9e-11 43.5 0.0 6.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Flavi_NS1 PF00948.16 EGG07198.1 - 0.1 10.9 0.1 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 PLA2_B PF01735.13 EGG07200.1 - 6.3e-81 272.0 0.5 2.8e-60 203.9 0.0 2.3 2 0 0 2 2 2 2 Lysophospholipase catalytic domain PLA2_B PF01735.13 EGG07201.1 - 2.7e-32 111.6 0.0 4e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.13 EGG07202.1 - 7e-87 291.6 0.0 1.1e-86 291.0 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Plant_tran PF04827.9 EGG07203.1 - 1.1e-22 80.4 0.1 1.5e-22 79.9 0.1 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.1 EGG07203.1 - 6.1e-07 29.1 0.3 9.5e-07 28.5 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Abhydrolase_5 PF12695.2 EGG07204.1 - 2.5e-11 43.5 0.2 4.8e-11 42.5 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGG07204.1 - 8.4e-11 41.4 0.2 2e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGG07204.1 - 1.7e-06 28.0 2.0 3.3e-05 23.8 1.4 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG07204.1 - 4.8e-06 26.2 0.1 1.4e-05 24.7 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 EGG07204.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 EGG07204.1 - 0.019 14.4 0.0 0.22 10.9 0.0 2.3 1 1 2 3 3 3 0 Phospholipase/Carboxylesterase LIP PF03583.9 EGG07204.1 - 0.11 11.7 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Secretory lipase MFS_1 PF07690.11 EGG07205.1 - 1.6e-09 36.9 37.2 2.8e-09 36.1 23.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MPC PF03650.8 EGG07206.1 - 6.5e-37 126.1 0.7 7.2e-37 125.9 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) cobW PF02492.14 EGG07207.1 - 9.9e-33 113.0 0.0 1.3e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EGG07207.1 - 3.9e-05 22.5 0.1 0.00011 21.0 0.0 1.6 2 0 0 2 2 2 1 ArgK protein ANTH PF07651.11 EGG07208.1 - 2.5e-71 239.6 0.0 2.5e-71 239.6 0.0 3.2 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EGG07208.1 - 8.8e-59 197.8 7.9 8.8e-59 197.8 5.5 4.9 4 1 0 5 5 5 1 I/LWEQ domain ENTH PF01417.15 EGG07208.1 - 2.4e-06 27.4 0.4 2.9e-05 23.9 0.0 3.2 3 0 0 3 3 3 1 ENTH domain Peptidase_M50 PF02163.17 EGG07209.1 - 0.1 11.5 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M50 Lactonase PF10282.4 EGG07210.1 - 4.1e-50 170.8 0.0 7e-50 170.0 0.0 1.3 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PXA PF02194.10 EGG07214.1 - 7.9e-10 38.5 0.1 9.7e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 PXA domain Glyco_hydro_7 PF00840.15 EGG07216.1 - 7.1e-130 433.2 2.6 8.3e-130 433.0 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Pacifastin_I PF05375.8 EGG07216.1 - 1.5 8.4 9.0 0.12 11.9 1.8 2.6 2 1 0 2 2 2 0 Pacifastin inhibitor (LCMII) Mannosyl_trans3 PF11051.3 EGG07217.1 - 3.3e-40 138.1 0.0 2.1e-39 135.5 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_hydro_16 PF00722.16 EGG07218.1 - 2.2e-06 27.0 0.1 5.2e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF915 PF06028.6 EGG07218.1 - 0.022 13.8 0.1 0.037 13.1 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) IL13 PF03487.8 EGG07221.1 - 0.0014 18.3 1.5 0.0028 17.3 1.1 1.5 1 0 0 1 1 1 1 Interleukin-13 COMPASS-Shg1 PF05205.7 EGG07221.1 - 0.098 12.9 8.9 2.6 8.3 0.2 4.4 1 1 2 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF1943 PF09172.6 EGG07221.1 - 0.18 10.6 23.9 0.27 10.0 2.1 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF1943) DUF3813 PF12758.2 EGG07222.1 - 0.037 14.1 0.9 0.07 13.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Lip_prot_lig_C PF10437.4 EGG07222.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Toxin_trans PF07952.7 EGG07222.1 - 0.18 10.6 0.7 0.21 10.4 0.0 1.4 2 0 0 2 2 2 0 Clostridium neurotoxin, Translocation domain Lipase_GDSL PF00657.17 EGG07223.1 - 0.0028 17.5 0.0 0.0031 17.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GNAT_acetyltran PF12746.2 EGG07223.1 - 0.055 12.2 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase HAT PF02184.11 EGG07224.1 - 9.4e-25 86.0 51.8 2e-12 46.6 0.0 14.7 14 1 0 14 14 14 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EGG07224.1 - 1.2e-19 68.9 16.5 0.051 14.2 0.0 12.0 5 3 8 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGG07224.1 - 1e-12 48.1 0.1 0.0044 17.3 0.0 7.8 6 1 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGG07224.1 - 6.3e-11 42.6 17.5 0.038 14.6 0.0 8.3 4 3 5 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGG07224.1 - 2e-07 30.5 8.1 0.086 12.4 0.0 6.5 7 1 1 8 8 8 2 TPR repeat TPR_2 PF07719.12 EGG07224.1 - 5.5e-06 25.9 19.8 0.96 9.5 0.0 9.2 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG07224.1 - 1.8e-05 24.5 14.5 0.059 13.3 0.1 7.1 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGG07224.1 - 8.8e-05 22.4 1.4 0.21 11.8 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat SNAP PF14938.1 EGG07224.1 - 0.00067 18.8 4.4 0.0017 17.5 0.7 2.9 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 EGG07224.1 - 0.0012 18.4 11.6 6.1 6.8 0.0 7.6 10 0 0 10 10 9 1 Tetratricopeptide repeat PPR_3 PF13812.1 EGG07224.1 - 0.044 14.0 1.1 5.7 7.4 0.0 4.7 4 0 0 4 4 3 0 Pentatricopeptide repeat domain TPR_6 PF13174.1 EGG07224.1 - 0.046 14.1 16.8 74 4.1 0.0 9.7 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGG07224.1 - 0.064 12.8 2.1 38 4.1 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat GrpE PF01025.14 EGG07224.1 - 3 7.3 10.1 0.045 13.3 0.7 2.5 3 0 0 3 3 3 0 GrpE Cnd2 PF05786.9 EGG07226.1 - 1.3e-126 423.9 34.4 2.4e-125 419.7 17.1 3.8 1 1 0 2 2 2 1 Condensin complex subunit 2 FAM72 PF14976.1 EGG07230.1 - 0.0077 16.0 2.0 0.017 15.0 1.4 1.4 1 0 0 1 1 1 1 FAM72 protein Macoilin PF09726.4 EGG07231.1 - 0.16 10.2 14.5 0.17 10.0 10.1 1.1 1 0 0 1 1 1 0 Transmembrane protein ANKH PF07260.6 EGG07232.1 - 0.053 12.4 0.1 0.071 12.0 0.1 1.1 1 0 0 1 1 1 0 Progressive ankylosis protein (ANKH) DUF2347 PF09804.4 EGG07232.1 - 0.059 12.6 0.1 0.086 12.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) zf-RING_2 PF13639.1 EGG07233.1 - 2.5e-06 27.1 0.9 1.2e-05 24.9 0.6 2.2 1 0 0 1 1 1 1 Ring finger domain DUF496 PF04363.7 EGG07233.1 - 0.00064 19.4 2.1 2.6 7.9 0.0 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF496) Rad50_zn_hook PF04423.9 EGG07233.1 - 0.15 11.5 0.7 0.53 9.8 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif MFS_1 PF07690.11 EGG07234.1 - 1.4e-11 43.7 23.3 1.4e-11 43.7 16.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGG07234.1 - 0.076 12.8 1.9 0.31 10.8 0.1 2.7 2 1 0 2 2 2 0 MFS_1 like family Alpha_kinase PF02816.13 EGG07236.1 - 0.00012 21.8 0.0 0.00025 20.7 0.0 1.5 1 1 0 1 1 1 1 Alpha-kinase family DUF1325 PF07039.6 EGG07238.1 - 6.5e-23 80.7 0.0 1.2e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain NAD_binding_10 PF13460.1 EGG07240.1 - 1.3e-17 64.3 0.0 1.9e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGG07240.1 - 1.4e-11 44.2 0.0 4.3e-10 39.4 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EGG07240.1 - 4e-11 42.6 0.0 5.2e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EGG07240.1 - 2.6e-09 36.2 0.0 1.6e-08 33.5 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGG07240.1 - 1.1e-08 34.3 0.0 0.0031 16.4 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.7 EGG07240.1 - 3.3e-07 29.5 0.0 0.00019 20.4 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.20 EGG07240.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGG07240.1 - 0.11 11.4 0.0 0.48 9.2 0.0 2.0 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein Translin PF01997.11 EGG07243.1 - 2.8e-24 85.8 0.1 3e-24 85.7 0.1 1.0 1 0 0 1 1 1 1 Translin family CNH PF00780.17 EGG07244.1 - 7.3e-71 238.8 0.0 1.9e-70 237.4 0.0 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EGG07244.1 - 1.5e-45 154.4 0.1 3e-45 153.4 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EGG07244.1 - 4.9e-36 124.2 0.2 7.6e-36 123.6 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EGG07244.1 - 1.3e-12 47.2 0.0 3.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 EGG07244.1 - 0.00024 21.2 0.0 0.00063 19.9 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_10 PF15411.1 EGG07244.1 - 0.067 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain ATPgrasp_YheCD PF14398.1 EGG07246.1 - 0.011 14.5 0.1 3.2 6.4 0.0 2.2 1 1 1 2 2 2 0 YheC/D like ATP-grasp Pkinase PF00069.20 EGG07247.1 - 3.6e-72 242.6 0.0 4.9e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG07247.1 - 1.3e-35 122.6 0.0 2.1e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG07247.1 - 0.0053 16.5 0.1 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGG07247.1 - 0.024 14.2 0.4 0.042 13.4 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EGG07247.1 - 0.032 13.5 0.1 0.11 11.8 0.1 1.7 1 1 1 2 2 2 0 RIO1 family Kdo PF06293.9 EGG07247.1 - 0.043 12.8 0.1 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGG07247.1 - 0.12 11.3 0.0 0.28 10.1 0.0 1.6 1 0 0 1 1 1 0 Kinase-like dCMP_cyt_deam_1 PF00383.17 EGG07248.1 - 1.7e-24 85.4 0.9 2.4e-24 84.9 0.6 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 EGG07248.1 - 0.0051 16.5 0.1 0.0089 15.7 0.1 1.4 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase FCH PF00611.18 EGG07249.1 - 3.9e-11 42.9 0.3 1.8e-10 40.8 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EGG07249.1 - 1.5e-08 34.4 0.2 3.6e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain Acetyltransf_1 PF00583.19 EGG07250.1 - 4.3e-15 55.5 0.0 6.3e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGG07250.1 - 3.3e-10 40.0 0.0 4.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGG07250.1 - 2.2e-09 37.3 0.0 3.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGG07250.1 - 1.2e-08 34.5 0.1 1.9e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EGG07250.1 - 8.1e-08 32.2 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGG07250.1 - 2.5e-06 27.3 0.0 4.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGG07250.1 - 0.00027 21.1 0.0 0.00038 20.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGG07250.1 - 0.0021 18.0 0.1 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGG07250.1 - 0.0077 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF2196 PF09962.4 EGG07250.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) Acetyltransf_13 PF13880.1 EGG07250.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase IMS PF00817.15 EGG07252.1 - 2.9e-42 143.9 0.0 5.3e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGG07252.1 - 2.3e-13 50.1 0.0 6.2e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 EGG07252.1 - 3.1e-07 30.4 0.0 6.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGG07252.1 - 1.6e-05 24.6 0.1 3.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 EGG07252.1 - 0.018 15.0 0.1 0.13 12.3 0.0 2.5 2 0 0 2 2 2 0 IMS family HHH motif FAM101 PF15068.1 EGG07255.1 - 0.1 12.0 0.9 0.17 11.2 0.6 1.3 1 0 0 1 1 1 0 FAM101 family BESS PF02944.15 EGG07256.1 - 0.097 12.2 0.1 1.5 8.4 0.2 2.3 2 0 0 2 2 2 0 BESS motif LRR_4 PF12799.2 EGG07257.1 - 0.2 11.3 9.6 0.87 9.2 0.2 4.0 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG07257.1 - 0.23 11.2 4.3 6.5 6.5 1.8 3.2 2 1 1 3 3 3 0 Leucine rich repeat ACP_syn_III PF08545.5 EGG07258.1 - 0.1 12.2 0.1 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.17 EGG07258.1 - 0.75 8.7 18.9 1.1 8.1 13.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Aa_trans PF01490.13 EGG07260.1 - 1.6e-13 49.9 0.2 5.8e-08 31.6 1.3 2.4 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein PI3K_1B_p101 PF10486.4 EGG07260.1 - 4.2 4.8 8.4 6.4 4.2 5.8 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop14 PF04147.7 EGG07260.1 - 9.9 3.9 15.5 17 3.1 10.7 1.3 1 0 0 1 1 1 0 Nop14-like family Acatn PF13000.2 EGG07261.1 - 8.1e-126 420.7 40.4 7e-87 292.1 14.5 4.5 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Porin_3 PF01459.17 EGG07262.1 - 5.2e-65 219.4 0.2 5.7e-65 219.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Nudix_N_2 PF14803.1 EGG07264.1 - 0.53 10.0 0.2 0.53 10.0 0.2 3.6 3 1 1 4 4 4 0 Nudix N-terminal zf-Mss51 PF13824.1 EGG07264.1 - 0.62 9.9 9.8 1.6 8.6 6.8 1.9 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ral PF11058.3 EGG07264.1 - 0.66 9.3 3.0 0.92 8.9 2.1 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral Peptidase_C74 PF12387.3 EGG07264.1 - 1.3 8.1 3.9 1.8 7.6 2.7 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Zn-ribbon_8 PF09723.5 EGG07264.1 - 2.5 8.1 14.7 0.42 10.6 1.6 2.5 2 1 0 2 2 2 0 Zinc ribbon domain UPF0167 PF03691.9 EGG07265.1 - 4.9 6.5 10.9 1 8.7 1.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) Ribosomal_L44 PF00935.14 EGG07265.1 - 9.3 6.3 7.9 1.8e+02 2.2 5.5 2.3 1 1 0 1 1 1 0 Ribosomal protein L44 Tnp_zf-ribbon_2 PF13842.1 EGG07265.1 - 9.5 6.7 18.1 1.6e+02 2.8 11.4 3.0 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DUF2312 PF10073.4 EGG07267.1 - 0.12 11.7 0.0 5.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Antimicrobial14 PF08109.6 EGG07268.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Lactocin 705 family Dicty_REP PF05086.7 EGG07268.1 - 0.71 7.5 16.4 0.92 7.1 11.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ribosomal_L32p PF01783.18 EGG07272.1 - 0.037 14.1 3.4 0.3 11.3 0.0 2.8 3 0 0 3 3 3 0 Ribosomal L32p protein family DUF962 PF06127.6 EGG07272.1 - 0.078 12.8 0.5 0.17 11.8 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Baculo_PEP_C PF04513.7 EGG07273.1 - 0.011 15.5 0.9 0.011 15.5 0.6 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mcm10 PF09332.6 EGG07275.1 - 0.12 11.7 4.1 0.15 11.3 2.8 1.2 1 0 0 1 1 1 0 Mcm10 replication factor Mitofilin PF09731.4 EGG07275.1 - 2.5 6.6 8.9 3 6.3 6.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3826 PF12875.2 EGG07275.1 - 6.3 6.4 8.7 15 5.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3826) DUF605 PF04652.11 EGG07277.1 - 0.082 12.2 7.2 0.12 11.7 5.0 1.2 1 0 0 1 1 1 0 Vta1 like Zn_clus PF00172.13 EGG07277.1 - 0.32 10.9 9.0 5.9 6.8 0.2 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Draxin PF15550.1 EGG07278.1 - 0.29 10.7 4.5 0.33 10.5 2.8 1.4 1 1 0 1 1 1 0 Draxin DUF4398 PF14346.1 EGG07278.1 - 2.5 8.2 10.2 1.9 8.5 5.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) CCDC-167 PF15188.1 EGG07278.1 - 3.1 7.8 6.3 14 5.6 3.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 FAR1 PF03101.10 EGG07279.1 - 1.1e-05 25.8 2.2 2.6e-05 24.6 1.5 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EGG07279.1 - 0.00016 21.8 0.7 0.00037 20.6 0.2 1.9 2 0 0 2 2 2 1 Transcription factor AFT Fumerase_C PF05683.7 EGG07279.1 - 0.015 14.4 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 Fumarase C-terminus UL73_N PF12522.3 EGG07283.1 - 8 6.1 12.7 17 5.0 8.8 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal CCDC-167 PF15188.1 EGG07284.1 - 0.0082 16.0 0.2 0.016 15.1 0.1 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 TPR_11 PF13414.1 EGG07284.1 - 0.019 14.5 0.1 0.055 13.1 0.0 1.7 1 0 0 1 1 1 0 TPR repeat Helitron_like_N PF14214.1 EGG07286.1 - 0.0007 19.3 0.0 0.00084 19.1 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus SIMPL PF04402.9 EGG07286.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) DUF3168 PF11367.3 EGG07286.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) Surp PF01805.15 EGG07287.1 - 1.1e-12 47.3 0.4 3.2e-11 42.7 0.1 2.5 2 0 0 2 2 2 1 Surp module RRM_1 PF00076.17 EGG07287.1 - 1.4e-06 27.8 0.0 0.0087 15.6 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.3 EGG07287.1 - 4.4e-05 23.1 0.1 7.2e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.8 EGG07287.1 - 0.0011 19.1 0.4 0.005 17.0 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RRM_6 PF14259.1 EGG07287.1 - 0.012 15.5 0.0 0.07 13.1 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG07287.1 - 0.034 14.0 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S8e PF01201.17 EGG07288.1 - 4.8e-33 114.1 4.4 4e-32 111.1 3.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3752 PF12572.3 EGG07288.1 - 0.71 9.9 13.5 1.1 9.4 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Aldo_ket_red PF00248.16 EGG07289.1 - 1.6e-65 220.7 0.0 1.8e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mak10 PF04112.8 EGG07291.1 - 7e-25 87.1 0.3 1.4e-24 86.2 0.2 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Pkinase PF00069.20 EGG07292.1 - 5.3e-53 179.8 0.0 6.5e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG07292.1 - 5e-31 107.7 0.0 1.3e-30 106.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG07292.1 - 2e-05 23.7 0.0 3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGG07292.1 - 0.0041 16.8 0.0 0.015 15.0 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family SARA PF11409.3 EGG07292.1 - 0.016 15.1 2.4 0.077 12.9 0.1 2.3 2 0 0 2 2 2 0 Smad anchor for receptor activation (SARA) ATPase_gene1 PF09527.5 EGG07293.1 - 0.023 14.5 2.0 0.023 14.5 1.4 3.1 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) ATPase_gene1 PF09527.5 EGG07294.1 - 0.025 14.3 1.6 0.025 14.3 1.1 3.1 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) ATG27 PF09451.5 EGG07295.1 - 1.7e-33 116.0 0.0 2.5e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EGG07295.1 - 3.6e-07 30.0 0.0 0.00086 19.0 0.0 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF4131 PF13567.1 EGG07296.1 - 0.012 15.0 1.7 1.7 8.0 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pox_A14 PF05767.7 EGG07296.1 - 0.16 11.9 5.3 0.28 11.1 0.7 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 BRCT_assoc PF12820.2 EGG07299.1 - 0.013 15.2 0.1 0.017 14.9 0.1 1.1 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT LysM PF01476.15 EGG07300.1 - 1.1e-05 25.2 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 LysM domain CASP_C PF08172.7 EGG07301.1 - 2.7e-66 223.1 3.7 2.7e-66 223.1 2.6 4.0 2 1 1 3 3 3 1 CASP C terminal Pedibin PF08182.6 EGG07301.1 - 0.25 10.8 8.5 0.73 9.3 0.7 4.0 3 0 0 3 3 3 0 Pedibin/Hym-346 family DUF2586 PF10758.4 EGG07301.1 - 1.4 7.9 7.7 0.16 11.0 1.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2586) MtrG PF04210.8 EGG07301.1 - 1.5 8.5 4.2 19 5.0 0.0 3.5 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G TORC_N PF12884.2 EGG07301.1 - 5.7 7.5 11.1 2.7 8.5 1.5 4.2 4 0 0 4 4 4 0 Transducer of regulated CREB activity, N terminus Rhodanese PF00581.15 EGG07305.1 - 1e-16 61.3 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain RPEL PF02755.10 EGG07307.1 - 3.7e-14 51.5 5.0 3.3e-07 29.4 0.1 2.6 3 0 0 3 3 3 2 RPEL repeat Dppa2_A PF14049.1 EGG07308.1 - 3.7 7.4 6.7 0.61 9.9 0.3 2.4 2 1 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates TK PF00265.13 EGG07309.1 - 0.23 11.0 0.6 0.64 9.5 0.5 1.6 2 0 0 2 2 2 0 Thymidine kinase NDUF_B12 PF08122.7 EGG07310.1 - 4.5e-16 58.3 0.3 5.3e-16 58.0 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Tyrosinase PF00264.15 EGG07311.1 - 5.6e-27 95.3 3.9 8.5e-27 94.7 2.7 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase LRR_6 PF13516.1 EGG07313.1 - 0.014 15.4 5.1 3.7 7.9 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 EGG07313.1 - 1.2 9.5 8.5 14 6.3 0.0 5.1 5 0 0 5 5 5 0 Leucine rich repeat DAP10 PF07213.6 EGG07315.1 - 0.038 13.7 0.2 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 DAP10 membrane protein CcmD PF04995.9 EGG07315.1 - 0.1 12.3 0.1 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF1674 PF07896.7 EGG07316.1 - 1e-11 44.8 3.0 1.4e-11 44.4 2.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) DUF1279 PF06916.8 EGG07317.1 - 3.9e-18 65.5 1.6 1.3e-17 63.9 1.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Aminotran_4 PF01063.14 EGG07318.1 - 2.8e-25 89.1 0.0 3.4e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 EGG07319.1 - 9.4e-40 136.3 0.0 3.6e-39 134.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG07319.1 - 4.3e-24 84.9 0.0 1.7e-22 79.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EGG07319.1 - 0.09 12.1 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ATP-synt_DE_N PF02823.11 EGG07320.1 - 2.8e-21 75.0 0.2 3.7e-21 74.6 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF3373 PF11853.3 EGG07320.1 - 0.063 11.8 0.0 0.065 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) PWWP PF00855.12 EGG07321.1 - 2e-19 69.5 0.0 7.5e-19 67.7 0.0 2.0 1 0 0 1 1 1 1 PWWP domain Med26 PF08711.6 EGG07321.1 - 0.011 15.2 0.1 0.021 14.3 0.1 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain BRCT PF00533.21 EGG07323.1 - 6.9e-07 29.3 0.3 0.027 14.6 0.1 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Pyridox_oxidase PF01243.15 EGG07324.1 - 2.6e-09 36.9 0.0 4.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M48 PF01435.13 EGG07326.1 - 2.9e-27 95.7 0.0 4.3e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 HEXIM PF15313.1 EGG07330.1 - 1 9.5 9.5 0.16 12.1 3.1 2.0 1 1 1 2 2 2 0 Hexamethylene bis-acetamide-inducible protein Yae1_N PF09811.4 EGG07330.1 - 3.6 7.2 4.7 66 3.1 0.1 3.7 4 0 0 4 4 4 0 Essential protein Yae1, N terminal SPC22 PF04573.7 EGG07331.1 - 3.5e-40 137.0 0.0 4.1e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Nucleo_P87 PF07267.6 EGG07332.1 - 3.3 6.2 5.9 4 5.9 4.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PAT1 PF09770.4 EGG07332.1 - 4.3 5.4 19.8 5 5.2 13.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FtsJ PF01728.14 EGG07334.1 - 2.1e-32 112.5 0.0 2.5e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase TIR PF01582.15 EGG07335.1 - 0.081 12.3 0.3 0.12 11.8 0.2 1.1 1 0 0 1 1 1 0 TIR domain TT_ORF2 PF02957.10 EGG07335.1 - 0.16 12.6 0.3 0.2 12.3 0.2 1.2 1 0 0 1 1 1 0 TT viral ORF2 PALP PF00291.20 EGG07336.1 - 6.5e-60 202.9 0.0 7.3e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GIDA PF01134.17 EGG07337.1 - 1.8e-152 507.7 0.0 2.6e-152 507.2 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EGG07337.1 - 3.6e-14 52.5 0.0 1.7e-13 50.3 0.0 2.2 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EGG07337.1 - 4.5e-09 36.4 0.2 1.1e-08 35.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGG07337.1 - 3.7e-05 22.9 0.2 6.4e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGG07337.1 - 0.00038 19.0 1.6 0.48 8.8 0.1 3.3 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.19 EGG07337.1 - 0.003 16.4 0.7 0.0076 15.1 0.5 1.7 1 0 0 1 1 1 1 FAD binding domain DJ-1_PfpI PF01965.19 EGG07337.1 - 0.045 13.2 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Protoglobin PF11563.3 EGG07338.1 - 6.8e-23 81.0 0.1 5.4e-13 48.8 0.0 2.1 2 0 0 2 2 2 2 Protoglobin Nuc_sug_transp PF04142.10 EGG07339.1 - 3.5e-61 206.4 6.5 3.9e-61 206.2 4.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EGG07339.1 - 2e-08 33.4 6.3 2.6e-08 33.1 4.4 1.1 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EGG07339.1 - 3.8e-06 27.0 1.7 3.8e-06 27.0 1.2 2.3 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 EGG07339.1 - 4.4e-05 23.1 3.5 4.4e-05 23.1 2.4 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGG07339.1 - 0.00011 22.2 5.8 0.00011 22.2 4.1 2.5 3 1 0 3 3 3 1 EamA-like transporter family Sugar_transport PF06800.7 EGG07339.1 - 0.095 11.7 5.2 0.17 10.9 1.7 2.3 2 1 0 2 2 2 0 Sugar transport protein Tim17 PF02466.14 EGG07340.1 - 2.7e-33 114.7 7.2 3.2e-33 114.5 5.0 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family F-box-like PF12937.2 EGG07341.1 - 0.0038 16.9 0.6 0.019 14.6 0.4 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EGG07341.1 - 0.074 12.7 5.1 0.41 10.3 0.1 3.6 4 0 0 4 4 4 0 F-box domain FAD_binding_1 PF00667.15 EGG07344.1 - 2.5e-57 193.8 0.0 1.7e-38 132.2 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain Flavodoxin_1 PF00258.20 EGG07344.1 - 4.6e-36 123.9 1.3 6.5e-36 123.4 0.4 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EGG07344.1 - 3.4e-23 82.2 0.3 1.2e-21 77.3 0.0 3.0 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 EGG07344.1 - 0.00086 19.2 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 NrdI Flavodoxin like Phos_pyr_kin PF08543.7 EGG07345.1 - 5.1e-82 274.7 0.1 1e-81 273.7 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EGG07345.1 - 1.3e-47 162.2 0.1 1.6e-47 161.9 0.1 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EGG07345.1 - 2.3e-08 33.5 0.0 3.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Spt20 PF12090.3 EGG07345.1 - 0.1 11.9 0.0 4.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Spt20 family RicinB_lectin_2 PF14200.1 EGG07346.1 - 0.0017 18.6 0.8 0.41 11.0 0.0 2.6 2 2 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like GCS PF03074.11 EGG07347.1 - 1.6e-147 491.4 0.0 1.9e-147 491.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.8 EGG07347.1 - 0.0081 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) UPF0278 PF08745.6 EGG07347.1 - 0.062 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 UPF0278 family CBFD_NFYB_HMF PF00808.18 EGG07348.1 - 2.9e-10 40.0 0.7 4.5e-10 39.4 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGG07348.1 - 9.6e-05 22.4 0.2 0.00014 21.9 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RunxI PF08504.6 EGG07349.1 - 0.14 12.6 2.5 0.092 13.2 1.0 1.2 1 1 0 1 1 1 0 Runx inhibition domain PLA2_B PF01735.13 EGG07350.1 - 3.2e-82 276.2 4.8 2.1e-58 197.6 0.3 2.6 1 1 0 2 2 2 2 Lysophospholipase catalytic domain Scs3p PF10261.4 EGG07351.1 - 2.2e-47 161.0 11.1 8.9e-46 155.8 8.6 2.3 2 1 0 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM TMEM223 PF14640.1 EGG07351.1 - 0.0021 18.0 0.1 0.0048 16.8 0.1 1.6 2 0 0 2 2 2 1 Transmembrane protein 223 DUF2422 PF10337.4 EGG07351.1 - 0.016 14.0 0.2 0.033 12.9 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) Zn_clus PF00172.13 EGG07354.1 - 0.00012 21.9 9.1 0.00021 21.1 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S9 PF00380.14 EGG07355.1 - 1.3e-18 67.3 0.4 3.1e-18 66.1 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S9/S16 CUT PF02376.10 EGG07355.1 - 0.063 13.0 0.1 2.7 7.8 0.0 2.8 2 0 0 2 2 2 0 CUT domain Acetyltransf_1 PF00583.19 EGG07356.1 - 2.6e-13 49.7 0.0 4.4e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGG07356.1 - 1.2e-09 38.1 0.0 2.3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGG07356.1 - 3.4e-08 33.1 0.0 5.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EGG07356.1 - 0.00062 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGG07356.1 - 0.0089 16.1 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGG07356.1 - 0.031 14.2 0.1 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGG07356.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PEPCK_ATP PF01293.15 EGG07357.1 - 3e-216 718.4 0.0 3.7e-216 718.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase MobB PF03205.9 EGG07357.1 - 0.018 14.7 0.0 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGG07357.1 - 0.081 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGG07357.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain 2-Hacid_dh_C PF02826.14 EGG07359.1 - 2e-47 160.6 0.0 3.1e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGG07359.1 - 2.9e-22 78.5 0.0 3.6e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGG07359.1 - 0.014 15.2 0.0 0.13 12.1 0.0 2.2 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pkinase PF00069.20 EGG07360.1 - 2.5e-54 184.1 0.1 1.6e-53 181.4 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG07360.1 - 4.4e-22 78.4 0.0 7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG07360.1 - 0.00042 20.1 0.0 0.00087 19.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGG07360.1 - 0.0019 17.5 0.2 0.0061 15.9 0.1 1.8 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EGG07360.1 - 0.046 13.3 0.4 0.21 11.1 0.0 2.1 2 1 0 2 2 2 0 Choline/ethanolamine kinase Thaumatin PF00314.12 EGG07361.1 - 1.2e-59 201.3 8.9 1.4e-59 201.1 6.2 1.0 1 0 0 1 1 1 1 Thaumatin family FAD_binding_6 PF00970.19 EGG07362.1 - 2.4e-32 110.9 0.0 4.3e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGG07362.1 - 2.3e-25 89.2 0.0 4.3e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EGG07362.1 - 3e-07 30.4 0.0 5.3e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EGG07362.1 - 0.00018 21.4 0.0 0.00041 20.3 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain TPP_enzyme_N PF02776.13 EGG07363.1 - 1e-37 129.2 0.0 1.6e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGG07363.1 - 3.1e-25 88.5 0.0 9.4e-25 86.9 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EGG07363.1 - 3.1e-14 52.8 0.4 1.5e-13 50.6 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EGG07363.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase LRR_4 PF12799.2 EGG07364.1 - 5.8e-53 175.7 72.1 2.1e-07 30.3 0.7 13.1 7 5 2 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG07364.1 - 9.5e-47 156.5 70.3 7.2e-13 48.0 2.5 10.0 5 3 7 12 12 12 10 Leucine rich repeat PP2C PF00481.16 EGG07364.1 - 4.6e-45 153.9 0.1 3.3e-44 151.1 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.15 EGG07364.1 - 1.9e-24 86.0 0.0 3.2e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EGG07364.1 - 4.8e-22 74.5 70.2 0.001 18.7 0.2 19.1 19 1 1 20 20 20 9 Leucine Rich Repeat LRR_6 PF13516.1 EGG07364.1 - 1.1e-07 31.1 64.7 3 8.1 0.1 17.4 17 2 1 18 18 18 3 Leucine Rich repeat LRR_5 PF13306.1 EGG07364.1 - 2e-07 30.7 10.9 0.042 13.5 2.6 4.7 3 1 0 4 4 4 2 Leucine rich repeats (6 copies) RA PF00788.18 EGG07364.1 - 1.4e-06 28.7 0.0 2.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 EGG07364.1 - 5.9e-05 22.6 74.7 0.076 13.2 0.1 17.4 23 0 0 23 23 23 5 Leucine rich repeat LRR_9 PF14580.1 EGG07364.1 - 0.02 14.4 14.4 2.3 7.7 0.2 4.7 3 1 1 4 4 4 0 Leucine-rich repeat Peroxidase_2 PF01328.12 EGG07365.1 - 3.5e-08 32.4 1.9 6.4e-07 28.3 1.3 2.2 1 1 0 1 1 1 1 Peroxidase, family 2 Topo_C_assoc PF14370.1 EGG07366.1 - 0.0053 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal topoisomerase domain UDPG_MGDP_dh_N PF03721.9 EGG07368.1 - 2.4e-58 196.5 0.0 6.7e-58 195.1 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EGG07368.1 - 2.4e-34 117.6 0.1 3.1e-33 114.1 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EGG07368.1 - 1.1e-29 102.4 0.0 2.6e-29 101.2 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 EGG07368.1 - 0.0017 18.0 0.0 0.0069 16.1 0.0 2.1 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus OTCace PF00185.19 EGG07368.1 - 0.0072 16.2 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Saccharop_dh PF03435.13 EGG07368.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 EGG07368.1 - 0.053 13.3 0.0 1.6 8.5 0.0 2.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EGG07368.1 - 0.07 12.7 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 EGG07368.1 - 0.081 12.7 0.0 1.7 8.5 0.0 3.1 3 1 1 4 4 4 0 lactate/malate dehydrogenase, NAD binding domain DUF4116 PF13475.1 EGG07369.1 - 0.11 12.0 0.3 0.63 9.5 0.0 2.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4116) G-alpha PF00503.15 EGG07370.1 - 7.8e-86 288.1 0.0 1e-85 287.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGG07370.1 - 5.6e-14 51.7 1.2 6.7e-09 35.2 0.0 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EGG07370.1 - 0.00014 22.3 0.2 0.51 10.8 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein MCM PF00493.18 EGG07370.1 - 0.001 17.9 0.1 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family Gtr1_RagA PF04670.7 EGG07370.1 - 0.0016 17.6 2.0 0.19 10.8 0.0 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EGG07370.1 - 0.009 15.5 0.0 0.023 14.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EGG07370.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EGG07370.1 - 0.08 12.8 0.0 3.7 7.5 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase NMO PF03060.10 EGG07371.1 - 3.2e-58 197.4 1.0 1.7e-57 195.0 0.7 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGG07371.1 - 4.7e-09 35.6 0.4 4.7e-05 22.4 2.1 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 EGG07371.1 - 0.0017 17.3 0.4 0.0028 16.6 0.3 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EGG07371.1 - 0.0025 16.7 0.4 0.0036 16.1 0.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EGG07371.1 - 0.005 15.7 0.2 0.0088 15.0 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EGG07371.1 - 0.0061 15.8 0.3 0.011 15.0 0.2 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.9 EGG07371.1 - 0.085 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF561 PF04481.7 EGG07371.1 - 0.11 11.4 2.5 0.62 8.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF561) PPV_E1_N PF00524.13 EGG07372.1 - 0.37 11.0 5.3 0.11 12.7 0.3 2.4 2 0 0 2 2 2 0 E1 Protein, N terminal domain Rifin_STEVOR PF02009.11 EGG07374.1 - 0.025 14.2 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Rifin/stevor family ABC2_membrane_3 PF12698.2 EGG07374.1 - 0.049 12.6 0.1 0.049 12.6 0.1 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF912 PF06024.7 EGG07374.1 - 0.056 13.5 0.1 0.056 13.5 0.1 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1539 PF07560.6 EGG07374.1 - 0.46 10.3 4.1 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Glycophorin_A PF01102.13 EGG07374.1 - 0.92 9.2 12.4 0.16 11.7 2.6 3.1 1 1 1 2 2 2 0 Glycophorin A ETRAMP PF09716.5 EGG07374.1 - 5.8 6.9 7.7 62 3.6 2.8 3.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Aconitase PF00330.15 EGG07377.1 - 7.1e-159 529.2 0.0 6.9e-158 525.9 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGG07377.1 - 2.8e-34 118.0 0.0 4.8e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain OPT PF03169.10 EGG07378.1 - 3.6e-94 316.3 34.7 4.3e-94 316.1 24.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4470 PF14737.1 EGG07380.1 - 2.4e-12 46.4 0.0 4.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EGG07380.1 - 7.7e-09 35.0 0.2 2.3e-08 33.5 0.1 1.9 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 EGG07380.1 - 0.0033 17.3 0.0 0.044 13.7 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGG07380.1 - 0.0042 17.3 0.2 0.27 11.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGG07380.1 - 0.015 15.1 0.2 0.14 12.1 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2670 PF10875.3 EGG07381.1 - 0.0054 16.7 0.2 0.02 14.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2670) ApbA_C PF08546.6 EGG07386.1 - 3.4e-21 75.5 0.0 9.7e-21 74.0 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EGG07386.1 - 5.1e-16 58.4 0.0 9.2e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Septin PF00735.13 EGG07389.1 - 3.5e-115 383.8 0.0 4.7e-115 383.4 0.0 1.1 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 EGG07389.1 - 5.9e-07 28.8 0.0 1.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGG07389.1 - 6.4e-07 29.3 0.0 1.5e-06 28.1 0.0 1.6 2 0 0 2 2 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGG07389.1 - 3.5e-06 26.5 0.0 5.5e-05 22.6 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 EGG07389.1 - 8.4e-05 22.0 0.2 0.00022 20.6 0.1 1.7 1 1 0 1 1 1 1 Ras family ABC_tran PF00005.22 EGG07389.1 - 0.0017 18.6 0.8 0.044 14.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.13 EGG07389.1 - 0.002 17.8 0.8 0.25 10.9 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein PduV-EutP PF10662.4 EGG07389.1 - 0.002 17.6 0.8 0.069 12.6 0.2 2.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EGG07389.1 - 0.0023 18.0 0.2 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.11 EGG07389.1 - 0.0028 16.8 0.0 0.0058 15.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EGG07389.1 - 0.0049 17.3 0.0 0.014 15.8 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 EGG07389.1 - 0.0094 15.6 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EGG07389.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 EGG07389.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGG07389.1 - 0.019 14.9 0.2 0.052 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EGG07389.1 - 0.039 13.4 0.7 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF3987 PF13148.1 EGG07389.1 - 0.043 12.3 1.3 4.1 5.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3987) Dynamin_N PF00350.18 EGG07389.1 - 0.049 13.4 5.5 2.2 8.0 0.0 2.8 2 1 1 3 3 3 0 Dynamin family NACHT PF05729.7 EGG07389.1 - 0.05 13.2 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 EGG07389.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pox_A32 PF04665.7 EGG07389.1 - 0.075 12.3 0.1 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_28 PF13521.1 EGG07389.1 - 0.076 12.9 0.5 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 EGG07389.1 - 0.085 11.9 0.2 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Myc-LZ PF02344.10 EGG07389.1 - 0.96 9.1 5.6 0.91 9.1 0.2 2.5 2 0 0 2 2 2 0 Myc leucine zipper domain Cep57_CLD_2 PF14197.1 EGG07389.1 - 3.2 7.7 7.6 9.2 6.2 5.1 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Tim54 PF11711.3 EGG07390.1 - 6e-42 143.5 0.0 1.1e-41 142.7 0.0 1.4 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SDA1 PF05285.7 EGG07393.1 - 2.7 7.1 16.4 13 4.9 11.3 1.8 1 1 0 1 1 1 0 SDA1 Sigma70_ner PF04546.8 EGG07393.1 - 8 6.0 14.4 4.1 6.9 3.4 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Macoilin PF09726.4 EGG07393.1 - 9.7 4.3 8.3 12 4.0 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Sec3_C PF09763.4 EGG07394.1 - 3.9e-149 497.9 1.5 5.2e-149 497.5 1.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Vps52 PF04129.7 EGG07394.1 - 1.2e-06 27.4 0.3 5.5e-06 25.1 0.2 2.1 2 0 0 2 2 2 1 Vps52 / Sac2 family Syntaxin-6_N PF09177.6 EGG07394.1 - 0.16 12.4 3.3 16 5.9 0.1 3.8 3 0 0 3 3 3 0 Syntaxin 6, N-terminal RepA_C PF04796.7 EGG07397.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Plasmid encoded RepA protein DGF-1_4 PF11024.3 EGG07399.1 - 0.049 14.0 0.5 8.2 6.9 0.1 3.1 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Tox-REase-2 PF15646.1 EGG07399.1 - 0.083 12.7 0.7 0.24 11.3 0.2 2.0 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 2 BLVR PF06375.6 EGG07401.1 - 3.9 7.2 7.0 1.3 8.8 2.8 1.7 1 1 1 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Ebola_NP PF05505.7 EGG07402.1 - 2.6 5.9 6.8 2.9 5.8 4.7 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein PGM_PMM_II PF02879.11 EGG07404.1 - 1.2e-13 51.2 0.0 5.9e-13 49.0 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.11 EGG07404.1 - 1.1e-12 47.6 0.0 3.8e-08 32.8 0.0 3.1 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 EGG07404.1 - 5.4e-10 39.1 0.1 1.5e-09 37.7 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EGG07404.1 - 4.2e-05 23.5 0.0 7.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III RNase_Zc3h12a_2 PF14626.1 EGG07404.1 - 0.011 15.6 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain SAPS PF04499.10 EGG07406.1 - 2.5e-101 339.6 0.2 6.5e-101 338.3 0.0 1.7 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein E_Pc_C PF06752.7 EGG07407.1 - 0.013 15.0 0.0 0.039 13.4 0.0 1.8 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus PsbW PF07123.7 EGG07407.1 - 0.06 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) DUF1496 PF07383.7 EGG07409.1 - 0.00039 19.6 0.1 26 4.1 0.0 4.1 1 1 3 4 4 4 4 Protein of unknown function (DUF1496) Helicase_C PF00271.26 EGG07409.1 - 0.017 14.9 3.3 31 4.5 0.0 3.7 4 0 0 4 4 4 0 Helicase conserved C-terminal domain BTB PF00651.26 EGG07409.1 - 5.5 7.0 5.9 40 4.2 0.2 3.1 1 1 3 4 4 4 0 BTB/POZ domain Ebola_NP PF05505.7 EGG07410.1 - 0.078 11.0 3.9 0.099 10.6 2.7 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein NADH_dh_m_C1 PF15088.1 EGG07414.1 - 0.067 12.7 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Ribosomal_L14 PF00238.14 EGG07416.1 - 1.7e-33 114.9 0.0 1.9e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Mito_carr PF00153.22 EGG07418.1 - 2.6e-72 238.6 0.6 6.5e-26 89.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EGG07418.1 - 6.6e-15 53.1 3.9 4.7e-05 22.3 0.4 5.8 7 0 0 7 7 7 3 EF hand EF-hand_6 PF13405.1 EGG07418.1 - 1.8e-13 49.1 5.2 0.00043 19.9 0.2 5.5 6 0 0 6 6 6 3 EF-hand domain EF-hand_8 PF13833.1 EGG07418.1 - 1.4e-11 43.8 2.7 0.0036 16.8 0.7 5.4 4 2 1 5 5 5 2 EF-hand domain pair EF-hand_7 PF13499.1 EGG07418.1 - 9.4e-11 41.6 6.4 0.00018 21.5 0.8 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EGG07418.1 - 5.6e-07 28.6 1.0 0.055 12.8 0.7 4.0 4 0 0 4 4 4 2 EF hand MPLKIP PF15502.1 EGG07419.1 - 1.4e-10 42.0 3.7 1.6e-10 41.9 2.6 1.1 1 0 0 1 1 1 1 M-phase-specific PLK1-interacting protein Gag_spuma PF03276.9 EGG07419.1 - 1.1 7.4 4.3 1.4 7.1 2.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein WD40 PF00400.27 EGG07420.1 - 1.2e-46 154.9 12.8 6e-10 38.6 0.3 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat tRNA-synt_1 PF00133.17 EGG07421.1 - 5.8e-203 675.2 0.0 2.8e-202 672.9 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGG07421.1 - 6.8e-37 126.5 0.0 1.6e-36 125.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGG07421.1 - 8.4e-17 60.9 0.2 7.4e-08 31.4 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EGG07421.1 - 1.5e-05 24.4 0.0 0.083 12.1 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 EGG07421.1 - 9.6e-05 22.3 1.5 0.00023 21.1 1.1 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.14 EGG07421.1 - 0.0064 15.3 0.1 0.09 11.5 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1f PF01921.13 EGG07421.1 - 0.025 13.2 0.0 0.069 11.8 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_1c PF00749.16 EGG07421.1 - 0.052 12.2 0.1 1.7 7.2 0.0 3.0 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain TPR_11 PF13414.1 EGG07423.1 - 1.9e-13 49.8 0.9 4.2e-13 48.7 0.6 1.6 1 0 0 1 1 1 1 TPR repeat DUF4470 PF14737.1 EGG07423.1 - 8.3e-12 44.7 0.0 1.9e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.12 EGG07423.1 - 1.7e-06 27.4 0.6 0.009 15.8 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG07423.1 - 0.0009 19.1 3.4 0.14 12.1 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGG07423.1 - 0.0016 17.9 1.0 0.086 12.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGG07423.1 - 0.016 15.1 0.2 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGG07423.1 - 0.017 15.4 1.8 0.041 14.2 1.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGG07423.1 - 0.021 14.6 0.5 3.3 7.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGG07423.1 - 0.037 14.6 0.4 9.1 7.2 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGG07423.1 - 0.089 13.4 0.2 0.48 11.1 0.6 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGG07424.1 - 2e-11 43.3 0.3 4.1e-11 42.3 0.2 1.6 1 0 0 1 1 1 1 TPR repeat DUF4470 PF14737.1 EGG07424.1 - 8e-11 41.5 0.0 1.5e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.12 EGG07424.1 - 6.7e-05 22.4 0.2 0.24 11.3 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG07424.1 - 0.00036 20.4 0.7 0.0013 18.6 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGG07424.1 - 0.0067 15.9 0.4 0.058 13.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGG07424.1 - 0.094 12.6 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3337 PF11816.3 EGG07426.1 - 9.3e-36 123.8 0.4 2.3e-33 115.9 0.2 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EGG07426.1 - 1.7e-28 97.4 19.3 7.4e-08 31.9 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Ribosom_S12_S23 PF00164.20 EGG07431.1 - 8.1e-37 125.3 0.2 1e-36 125.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Cyclin_N PF00134.18 EGG07432.1 - 3.2e-11 42.8 0.4 3.2e-11 42.8 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EGG07432.1 - 0.00087 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat CAP_GLY PF01302.20 EGG07434.1 - 1e-06 28.3 0.1 1.6e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain AA_permease_N PF08403.5 EGG07434.1 - 0.02 14.2 0.1 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 Amino acid permease N-terminal DUF684 PF05075.9 EGG07434.1 - 0.11 11.0 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF684) Levi_coat PF01819.12 EGG07434.1 - 0.4 10.2 6.0 0.7 9.4 3.8 1.7 1 1 1 2 2 2 0 Levivirus coat protein InvH PF04741.7 EGG07434.1 - 1 9.1 6.1 1.6 8.5 4.2 1.2 1 0 0 1 1 1 0 InvH outer membrane lipoprotein ERM PF00769.14 EGG07435.1 - 0.0021 17.6 19.7 0.0021 17.6 13.7 3.4 2 2 1 3 3 3 1 Ezrin/radixin/moesin family APG6 PF04111.7 EGG07435.1 - 1.8 7.5 44.5 0.34 9.9 2.6 3.4 3 0 0 3 3 3 0 Autophagy protein Apg6 Baculo_PEP_C PF04513.7 EGG07435.1 - 4.3 7.1 16.2 4 7.2 1.4 4.1 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glycos_transf_1 PF00534.15 EGG07436.1 - 6.2e-20 71.3 0.0 9.5e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGG07436.1 - 1.1e-08 35.2 0.0 2.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Tmemb_9 PF05434.6 EGG07436.1 - 0.23 11.1 3.0 0.26 11.0 0.3 2.2 2 0 0 2 2 2 0 TMEM9 Ank PF00023.25 EGG07437.1 - 2.5e-12 45.9 0.0 7.1e-12 44.5 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeat ACBP PF00887.14 EGG07437.1 - 3.8e-11 42.4 0.0 7.9e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_2 PF12796.2 EGG07437.1 - 2.9e-09 37.1 0.1 1.4e-08 34.9 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGG07437.1 - 1.1e-07 31.4 0.0 3.1e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 EGG07437.1 - 1.4e-07 31.5 0.1 4.1e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGG07437.1 - 5.5e-06 26.7 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF3129 PF11327.3 EGG07437.1 - 0.064 13.0 0.0 5.9 6.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3129) CBFD_NFYB_HMF PF00808.18 EGG07439.1 - 2.3e-19 69.1 0.3 4.5e-19 68.2 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGG07439.1 - 0.00018 21.5 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RNA_pol_Rpc34 PF05158.7 EGG07439.1 - 0.0049 16.1 0.2 0.0056 15.9 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TAFII28 PF04719.9 EGG07439.1 - 0.013 15.2 0.6 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 hTAFII28-like protein conserved region TFIID-18kDa PF02269.11 EGG07439.1 - 0.039 13.7 0.1 0.076 12.8 0.1 1.7 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit ArgK PF03308.11 EGG07439.1 - 0.089 11.5 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 ArgK protein Apc5 PF12862.2 EGG07443.1 - 1.8e-07 30.9 4.4 1.8e-07 30.9 3.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 Pkinase PF00069.20 EGG07444.1 - 2.2e-22 79.4 0.0 3.6e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EGG07444.1 - 5.8e-16 57.6 8.9 1.3e-08 34.3 0.3 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 EGG07444.1 - 1.3e-08 34.2 0.0 2.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 EGG07444.1 - 4.5e-07 29.3 5.2 0.027 14.5 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EGG07444.1 - 1.5e-05 25.2 0.0 0.18 12.1 0.1 3.3 1 1 3 4 4 4 3 HEAT repeats APH PF01636.18 EGG07444.1 - 0.026 14.2 0.3 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2435 PF10363.4 EGG07444.1 - 0.026 14.3 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) Cnd1 PF12717.2 EGG07444.1 - 0.038 13.8 1.6 3.5 7.4 0.1 3.1 2 2 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Muskelin_N PF06588.6 EGG07447.1 - 2e-52 177.7 0.0 4.6e-52 176.6 0.0 1.5 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.1 EGG07447.1 - 3e-18 65.4 9.6 0.00012 22.1 0.0 7.6 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EGG07447.1 - 1.2e-16 60.1 6.2 0.003 17.3 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EGG07447.1 - 4.6e-15 55.1 0.0 0.0051 16.7 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 EGG07447.1 - 1.3e-12 47.2 0.2 0.4 10.9 0.0 7.4 8 0 0 8 8 8 2 Kelch motif Sad1_UNC PF07738.8 EGG07447.1 - 0.0001 22.1 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CLTH PF10607.4 EGG07447.1 - 0.0042 16.8 0.3 0.0081 15.8 0.2 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Kelch_1 PF01344.20 EGG07447.1 - 0.0092 15.5 2.5 24 4.5 0.0 4.9 6 0 0 6 6 6 0 Kelch motif F5_F8_type_C PF00754.20 EGG07447.1 - 0.11 12.3 0.0 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 F5/8 type C domain Kelch_2 PF07646.10 EGG07447.1 - 1.7 8.5 9.7 67 3.4 0.3 5.4 5 1 0 5 5 5 0 Kelch motif NPV_P10 PF05531.7 EGG07449.1 - 0.017 15.3 0.7 0.035 14.3 0.5 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Dynamitin PF04912.9 EGG07449.1 - 0.056 12.2 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Dynamitin DUF1993 PF09351.5 EGG07449.1 - 0.069 13.0 0.5 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DUF948 PF06103.6 EGG07449.1 - 0.13 12.1 1.3 0.26 11.1 0.9 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1298 PF06974.8 EGG07450.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) HAP1_N PF04849.8 EGG07451.1 - 0.0013 17.7 0.1 0.0018 17.2 0.1 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF4140 PF13600.1 EGG07451.1 - 0.07 13.5 2.0 0.14 12.6 1.4 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TSC22 PF01166.13 EGG07451.1 - 0.1 12.6 0.4 0.26 11.2 0.2 1.7 1 1 1 2 2 2 0 TSC-22/dip/bun family AA_kinase PF00696.23 EGG07452.1 - 1.5e-37 129.4 0.1 2.3e-37 128.8 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EGG07452.1 - 1.2e-13 50.5 0.1 4.7e-13 48.6 0.1 2.0 1 1 0 1 1 1 1 PUA domain 2-ph_phosp PF04029.9 EGG07452.1 - 0.089 11.7 0.2 0.63 8.9 0.0 2.1 2 0 0 2 2 2 0 2-phosphosulpholactate phosphatase SAP PF02037.22 EGG07453.1 - 8.4e-12 44.2 0.2 2e-11 43.0 0.2 1.7 1 0 0 1 1 1 1 SAP domain Spiralin PF05215.8 EGG07453.1 - 0.087 11.9 1.9 0.14 11.2 0.4 1.8 2 0 0 2 2 2 0 Spiralin PPR PF01535.15 EGG07455.1 - 0.018 15.0 0.2 47 4.2 0.0 5.0 5 1 0 5 5 5 0 PPR repeat PPR_3 PF13812.1 EGG07455.1 - 0.068 13.4 0.0 1.6e+02 2.9 0.0 4.7 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Transketolase_N PF00456.16 EGG07457.1 - 2.9e-08 32.9 0.1 5.3e-07 28.7 0.1 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.15 EGG07457.1 - 0.0095 14.6 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.15 EGG07457.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain LAG1-DNAbind PF09271.6 EGG07458.1 - 3.4e-31 108.5 0.0 6.9e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 EGG07458.1 - 2.2e-18 66.5 0.0 5.3e-15 55.5 0.0 3.4 2 1 0 2 2 2 2 Beta-trefoil DNA-binding domain YjbE PF11106.3 EGG07459.1 - 0.032 14.1 0.1 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE CUB PF00431.15 EGG07460.1 - 0.075 13.1 0.2 0.32 11.0 0.0 1.9 1 1 1 2 2 2 0 CUB domain Chromo_shadow PF01393.14 EGG07460.1 - 0.081 12.7 0.0 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 Chromo shadow domain DUF35_N PF12172.3 EGG07460.1 - 0.098 12.5 0.2 0.098 12.5 0.2 1.7 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) G_glu_transpept PF01019.16 EGG07461.1 - 5.2e-142 473.9 0.0 6e-142 473.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Wzz PF02706.10 EGG07461.1 - 0.031 14.1 0.2 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 Chain length determinant protein Sybindin PF04099.7 EGG07462.1 - 1e-19 70.6 0.0 2.3e-19 69.4 0.0 1.6 1 1 0 1 1 1 1 Sybindin-like family MFS_1 PF07690.11 EGG07463.1 - 6.5e-26 90.8 16.0 6.5e-26 90.8 11.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG07463.1 - 3e-06 26.1 3.9 3e-06 26.1 2.7 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EGG07463.1 - 0.00036 18.8 0.3 0.00036 18.8 0.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGG07463.1 - 0.0022 16.4 7.7 0.0038 15.6 0.4 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein DUF1295 PF06966.7 EGG07463.1 - 0.082 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF2431 PF10354.4 EGG07464.1 - 1.3e-33 116.2 0.2 3.3e-30 105.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) SCA7 PF08313.7 EGG07465.1 - 5.2e-28 96.4 0.4 5.2e-28 96.4 0.2 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain eIF3_subunit PF08597.5 EGG07465.1 - 0.96 8.9 13.0 0.11 12.0 3.8 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit FKBP_N PF01346.13 EGG07465.1 - 4.2 7.4 9.5 0.12 12.3 1.8 2.0 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF2956 PF11169.3 EGG07465.1 - 4.3 7.3 15.4 4.2 7.3 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF4570 PF15134.1 EGG07466.1 - 0.15 11.8 1.3 0.27 11.0 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) PLA2_B PF01735.13 EGG07467.1 - 5.9e-93 311.6 0.0 1e-92 310.8 0.0 1.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain DUF21 PF01595.15 EGG07469.1 - 8.3e-33 113.2 1.9 1.1e-32 112.8 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EGG07469.1 - 2.1e-08 33.7 0.2 0.0011 18.7 0.0 3.0 3 0 0 3 3 3 2 CBS domain PP1_bind PF15276.1 EGG07470.1 - 0.02 14.9 0.7 0.047 13.7 0.5 1.7 1 1 0 1 1 1 0 Protein phosphatase 1 binding Ebola_NP PF05505.7 EGG07470.1 - 0.22 9.5 3.9 0.24 9.4 2.7 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF3043 PF11241.3 EGG07470.1 - 0.39 10.2 2.3 0.48 10.0 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) BTV_NS2 PF04514.7 EGG07470.1 - 0.6 8.9 4.4 0.67 8.7 3.1 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Na_H_Exchanger PF00999.16 EGG07471.1 - 2.3e-46 158.0 28.4 2.7e-46 157.8 19.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NMO PF03060.10 EGG07472.1 - 8.7e-44 150.0 1.5 3.7e-43 147.9 1.0 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGG07472.1 - 3.4e-08 32.7 0.0 1.8e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGG07472.1 - 0.026 13.3 0.1 0.052 12.3 0.1 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase SUR7 PF06687.7 EGG07473.1 - 1.9e-17 63.5 1.4 1.9e-17 63.5 0.6 1.3 1 1 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.4 EGG07473.1 - 1.5 7.2 5.1 0.12 10.8 0.2 1.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) TPR_11 PF13414.1 EGG07474.1 - 3e-24 84.4 4.6 1.3e-11 43.9 0.9 3.3 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 EGG07474.1 - 3.6e-19 67.4 4.3 3.9e-07 29.3 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGG07474.1 - 2.6e-17 61.4 4.6 0.00017 21.5 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGG07474.1 - 2.3e-16 58.3 6.9 4e-06 26.3 0.2 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGG07474.1 - 9.7e-12 44.4 3.5 0.00056 20.3 0.1 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG07474.1 - 1.7e-11 43.8 4.2 3e-06 27.0 0.6 3.8 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGG07474.1 - 4.2e-11 41.7 8.5 0.00075 19.1 0.1 5.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGG07474.1 - 5.3e-11 42.8 1.5 1e-05 26.0 0.0 3.6 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGG07474.1 - 2.7e-09 37.2 2.9 0.00039 20.7 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGG07474.1 - 1.9e-07 30.3 3.8 0.0034 17.0 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EGG07474.1 - 1.5e-05 25.0 0.1 0.0012 18.9 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EGG07474.1 - 4e-05 23.6 1.0 0.72 9.9 0.1 4.2 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGG07474.1 - 0.00057 19.6 0.8 2.7 7.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGG07474.1 - 0.0051 17.1 3.0 12 6.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EGG07474.1 - 0.013 15.3 4.5 0.25 11.2 0.1 3.6 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 EGG07474.1 - 0.023 14.4 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 EGG07474.1 - 0.058 13.4 0.1 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Tetratrico peptide repeat TFIIA PF03153.8 EGG07475.1 - 2.3e-44 152.8 11.9 1.8e-28 100.5 8.3 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit HalX PF08663.5 EGG07475.1 - 0.14 12.1 2.6 0.37 10.7 1.8 1.7 1 0 0 1 1 1 0 HalX domain DUF1958 PF09211.5 EGG07475.1 - 0.34 11.0 3.1 0.21 11.6 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1958) bZIP_2 PF07716.10 EGG07476.1 - 2.8e-11 43.0 12.6 5.1e-11 42.2 8.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EGG07476.1 - 5.7e-05 22.9 8.7 0.00018 21.4 6.0 1.9 1 0 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.6 EGG07476.1 - 0.0019 17.8 2.6 0.0035 17.0 0.5 2.4 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region TSC22 PF01166.13 EGG07476.1 - 0.0028 17.5 1.1 0.0069 16.3 0.8 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_Maf PF03131.12 EGG07476.1 - 0.017 15.4 4.0 0.03 14.5 2.0 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Myb_DNA-bind_4 PF13837.1 EGG07476.1 - 0.019 15.1 3.2 0.041 14.0 2.2 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain XhlA PF10779.4 EGG07476.1 - 0.062 13.2 6.6 0.1 12.4 4.0 1.8 1 1 0 1 1 1 0 Haemolysin XhlA DDE_Tnp_IS240 PF13610.1 EGG07476.1 - 0.097 12.6 1.7 0.17 11.8 1.2 1.4 1 0 0 1 1 1 0 DDE domain DUF4482 PF14818.1 EGG07476.1 - 0.12 13.0 14.1 0.039 14.6 7.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) DUF972 PF06156.8 EGG07476.1 - 3.5 8.0 9.8 9.6 6.6 6.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Striatin PF08232.7 EGG07476.1 - 7.1 6.9 20.2 1.4 9.2 8.6 2.2 1 1 1 2 2 2 0 Striatin family Phosducin PF02114.11 EGG07477.1 - 2.5e-12 46.1 0.0 7.2e-07 28.1 0.0 3.1 3 0 0 3 3 3 3 Phosducin Methyltransf_26 PF13659.1 EGG07478.1 - 8.2e-11 41.9 0.0 1.7e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG07478.1 - 6.5e-10 38.6 0.0 2.9e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.1 EGG07478.1 - 2.1e-09 37.1 0.1 9.4e-08 31.7 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG07478.1 - 2.4e-08 34.5 0.0 7e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGG07478.1 - 6.4e-05 22.2 0.0 0.00018 20.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EGG07478.1 - 0.00012 22.4 0.0 0.00044 20.6 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_10 PF05971.7 EGG07478.1 - 0.00015 21.0 0.0 0.041 13.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF890) Methyltransf_12 PF08242.7 EGG07478.1 - 0.00029 21.2 0.0 0.02 15.3 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 EGG07478.1 - 0.00045 19.8 0.0 0.38 10.3 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 EGG07478.1 - 0.0011 18.0 0.0 0.003 16.6 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EGG07478.1 - 0.0015 18.8 0.0 0.0034 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG07478.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGG07478.1 - 0.057 13.0 0.2 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Josephin PF02099.12 EGG07479.1 - 1.2e-43 148.4 0.0 1.9e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Josephin UIM PF02809.15 EGG07479.1 - 4 7.2 10.7 16 5.3 1.3 3.3 2 0 0 2 2 2 0 Ubiquitin interaction motif Mito_fiss_reg PF05308.6 EGG07480.1 - 0.49 9.7 8.0 0.53 9.6 5.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-SNAP50_C PF12251.3 EGG07481.1 - 2e-29 102.4 1.2 8.3e-29 100.3 0.8 1.7 1 1 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Smr PF01713.16 EGG07482.1 - 5.7e-11 42.4 0.4 7.9e-11 42.0 0.1 1.4 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.5 EGG07482.1 - 4.7e-09 36.1 1.0 6.4e-09 35.6 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Telomere_reg-2 PF10193.4 EGG07483.1 - 3.5e-33 114.2 0.1 8.9e-33 112.9 0.1 1.8 1 0 0 1 1 1 1 Telomere length regulation protein OxoDH_E1alpha_N PF12573.3 EGG07484.1 - 0.041 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Homeobox PF00046.24 EGG07485.1 - 3.6e-21 74.5 3.0 3.9e-21 74.4 2.1 1.0 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EGG07485.1 - 0.034 13.2 0.3 0.048 12.7 0.2 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.17 EGG07485.1 - 0.091 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Homeobox_KN PF05920.6 EGG07485.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Homeobox KN domain DUF4446 PF14584.1 EGG07487.1 - 0.024 14.4 1.4 0.032 14.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Chordopox_A13L PF05961.6 EGG07487.1 - 1.5 8.7 4.3 2.6 8.0 2.0 1.9 1 1 1 2 2 2 0 Chordopoxvirus A13L protein PUCC PF03209.10 EGG07488.1 - 0.0057 15.4 3.4 0.0089 14.7 2.4 1.3 1 0 0 1 1 1 1 PUCC protein Rhodanese PF00581.15 EGG07489.1 - 1.9e-19 70.1 0.0 2.4e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain TIM PF00121.13 EGG07490.1 - 1.2e-87 293.0 0.0 1.4e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase L27_N PF09060.5 EGG07490.1 - 0.13 12.0 0.1 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 L27_N FlaC_arch PF05377.6 EGG07490.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DPBB_1 PF03330.13 EGG07491.1 - 0.0015 18.4 0.0 0.0028 17.6 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel WHIM2 PF15613.1 EGG07492.1 - 0.025 14.5 0.1 0.073 13.0 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Phage_integrase PF00589.17 EGG07494.1 - 0.0047 16.6 0.0 0.0055 16.3 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family DUF2784 PF10861.3 EGG07494.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) Mg_trans_NIPA PF05653.9 EGG07495.1 - 7.7e-97 323.8 23.3 1e-96 323.4 16.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EGG07495.1 - 9e-06 25.7 7.5 9e-06 25.7 5.2 4.3 3 1 1 4 4 4 1 EamA-like transporter family EmrE PF13536.1 EGG07495.1 - 0.00012 22.2 6.7 0.00012 22.2 4.6 3.6 1 1 2 3 3 3 1 Multidrug resistance efflux transporter GNVR PF13807.1 EGG07495.1 - 0.48 10.2 3.1 0.65 9.7 0.3 2.7 2 1 1 3 3 3 0 G-rich domain on putative tyrosine kinase tRNA-synt_2c PF01411.14 EGG07496.1 - 9.4e-210 697.5 0.0 1.2e-209 697.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EGG07496.1 - 1.2e-15 57.1 0.1 2.9e-15 55.8 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EGG07496.1 - 2.1e-08 33.7 0.6 7.2e-08 32.0 0.1 2.1 2 0 0 2 2 2 1 DHHA1 domain ODC_AZ PF02100.12 EGG07497.1 - 1e-14 53.9 0.0 2.9e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Ornithine decarboxylase antizyme DUF1250 PF06855.7 EGG07498.1 - 0.0049 16.3 0.5 0.017 14.6 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1250) Topoisom_I_N PF02919.10 EGG07499.1 - 3.3e-97 323.9 0.2 3.3e-97 323.9 0.1 2.8 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EGG07499.1 - 1.5e-84 282.8 3.0 3.6e-84 281.5 2.1 1.7 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EGG07499.1 - 1e-28 98.7 0.3 3.3e-28 97.1 0.2 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 EGG07499.1 - 0.01 14.9 0.1 0.025 13.7 0.0 1.6 1 0 0 1 1 1 0 RolB/RolC glucosidase family Ribosomal_S5 PF00333.15 EGG07500.1 - 2.7e-28 97.5 0.6 2.7e-28 97.5 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EGG07500.1 - 7.8e-22 76.3 0.1 1.2e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain F-box PF00646.28 EGG07501.1 - 1.6 8.4 7.1 0.96 9.1 0.4 2.7 2 0 0 2 2 2 0 F-box domain Myb_DNA-bind_3 PF12776.2 EGG07504.1 - 2.3e-09 37.7 0.4 4.9e-09 36.7 0.2 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Exo_endo_phos PF03372.18 EGG07505.1 - 9.1e-14 51.9 0.0 2.6e-13 50.4 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Med14 PF08638.6 EGG07506.1 - 2e-42 144.6 0.8 3.7e-42 143.7 0.6 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 DUF3385 PF11865.3 EGG07506.1 - 0.082 12.8 1.0 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Peroxin-22 PF12827.2 EGG07506.1 - 0.12 12.0 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family HHH PF00633.18 EGG07507.1 - 0.00052 19.5 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif ChlamPMP_M PF07548.6 EGG07507.1 - 0.031 14.0 1.4 0.053 13.2 1.0 1.3 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain HHH_5 PF14520.1 EGG07507.1 - 0.086 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain DMAP_binding PF06464.6 EGG07509.1 - 0.04 14.5 0.7 0.04 14.5 0.5 3.4 3 1 0 3 3 3 0 DMAP1-binding Domain DUF2439 PF10382.4 EGG07511.1 - 1.7e-13 50.5 0.8 5e-13 49.0 0.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2439) Glyco_hydro_92 PF07971.7 EGG07512.1 - 1.6e-99 333.8 0.1 4.8e-87 292.6 0.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 DUF1764 PF08576.5 EGG07513.1 - 0.65 10.8 7.4 0.82 10.4 4.7 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Sec8_exocyst PF04048.9 EGG07514.1 - 1.9e-12 46.9 4.9 2.5e-10 40.1 3.4 3.5 1 1 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EGG07514.1 - 0.039 12.8 1.2 0.11 11.3 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) WD40_alt PF14077.1 EGG07516.1 - 0.23 11.1 2.6 0.8 9.3 1.3 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif LSM PF01423.17 EGG07517.1 - 4.4e-18 64.5 0.1 5.5e-18 64.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain L27_1 PF09058.5 EGG07518.1 - 0.022 14.6 0.2 0.21 11.4 0.0 2.6 3 0 0 3 3 3 0 L27_1 DUF788 PF05620.6 EGG07518.1 - 6.6 6.5 11.8 0.055 13.3 1.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF788) SF3b1 PF08920.5 EGG07519.1 - 8.8e-34 116.6 0.0 8.8e-34 116.6 0.0 2.8 2 1 1 3 3 3 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EGG07519.1 - 1.5e-14 54.0 3.8 3.7e-05 23.9 0.1 6.9 7 1 1 8 8 8 3 HEAT repeats HEAT PF02985.17 EGG07519.1 - 2.1e-11 42.8 4.2 0.56 10.4 0.0 9.4 10 0 0 10 10 10 1 HEAT repeat HEAT_EZ PF13513.1 EGG07519.1 - 1.2e-09 38.3 0.8 0.12 12.9 0.0 8.1 7 2 2 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGG07519.1 - 2.8e-06 27.6 3.6 0.35 11.2 0.0 5.3 7 0 0 7 7 7 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EGG07519.1 - 1.6e-05 23.4 5.1 0.068 11.4 0.1 3.4 2 1 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 EGG07519.1 - 0.00014 21.3 1.5 0.54 9.5 0.0 3.8 4 0 0 4 4 4 2 CLASP N terminal TIP120 PF08623.5 EGG07519.1 - 0.007 15.9 0.1 0.81 9.2 0.0 3.2 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) Dopey_N PF04118.9 EGG07519.1 - 0.013 14.2 1.3 0.24 10.1 0.0 3.2 2 1 1 3 3 3 0 Dopey, N-terminal Cnd1 PF12717.2 EGG07519.1 - 0.09 12.6 4.8 23 4.7 0.0 5.0 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Metallophos PF00149.23 EGG07520.1 - 9.5e-39 132.8 0.3 1.3e-38 132.4 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DLH PF01738.13 EGG07521.1 - 2.8e-23 82.3 0.0 3.3e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGG07521.1 - 0.00017 21.3 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG07521.1 - 0.0071 16.2 0.0 0.56 10.0 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG07521.1 - 0.01 15.3 0.0 0.057 12.9 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Glyco_hydro_16 PF00722.16 EGG07523.1 - 0.032 13.5 0.1 0.063 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 PNP_UDP_1 PF01048.15 EGG07524.1 - 5.1e-09 35.4 0.0 5.8e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DBD_Tnp_Mut PF03108.10 EGG07525.1 - 0.01 15.4 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 1 MuDR family transposase AFT PF08731.6 EGG07525.1 - 0.06 13.5 1.0 0.29 11.3 0.0 2.3 2 0 0 2 2 2 0 Transcription factor AFT Sec2p PF06428.6 EGG07528.1 - 0.032 14.0 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Colicin_Pyocin PF01320.13 EGG07529.1 - 0.043 13.6 0.1 0.075 12.9 0.1 1.3 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein Capsule_synth PF05159.9 EGG07531.1 - 0.00013 21.4 0.0 0.00026 20.5 0.0 1.4 1 1 0 1 1 1 1 Capsule polysaccharide biosynthesis protein PspA_IM30 PF04012.7 EGG07532.1 - 0.011 15.0 3.0 0.02 14.2 2.1 1.4 1 0 0 1 1 1 0 PspA/IM30 family Phlebovirus_NSM PF07246.6 EGG07532.1 - 0.014 14.5 1.1 0.02 14.0 0.1 1.7 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF3580 PF12117.3 EGG07532.1 - 0.056 13.3 1.7 0.095 12.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3580) COG5 PF10392.4 EGG07532.1 - 0.52 10.2 7.3 0.15 12.0 2.4 2.1 2 1 0 2 2 2 0 Golgi transport complex subunit 5 SlyX PF04102.7 EGG07532.1 - 1.8 8.9 6.0 3.7 7.9 2.9 2.4 1 1 1 2 2 2 0 SlyX ATG16 PF08614.6 EGG07532.1 - 8.3 6.1 10.8 7.8 6.2 3.4 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.7 EGG07533.1 - 0.042 14.1 4.7 0.32 11.2 1.2 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein OTU PF02338.14 EGG07536.1 - 0.0017 18.9 0.0 0.005 17.4 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGG07536.1 - 0.0019 17.6 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase C65 Otubain Glyoxalase_4 PF13669.1 EGG07539.1 - 0.16 11.9 0.0 0.48 10.4 0.0 1.7 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily JAB PF01398.16 EGG07540.1 - 5.3e-05 22.9 0.1 6.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGG07540.1 - 0.056 13.5 0.0 0.089 12.8 0.0 1.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function MitMem_reg PF13012.1 EGG07541.1 - 6.8e-11 42.2 0.3 3.1e-10 40.1 0.2 1.8 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF3505 PF12013.3 EGG07544.1 - 2.4e-13 50.2 3.3 2.4e-13 50.2 2.3 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) BLVR PF06375.6 EGG07545.1 - 0.0078 16.0 7.8 0.01 15.6 5.4 1.2 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) NST1 PF13945.1 EGG07545.1 - 0.1 12.6 8.8 0.14 12.2 6.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Presenilin PF01080.12 EGG07545.1 - 1 8.1 2.6 1.4 7.7 1.8 1.1 1 0 0 1 1 1 0 Presenilin FLO_LFY PF01698.11 EGG07545.1 - 2.1 7.1 5.7 2.8 6.6 4.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2201_N PF13203.1 EGG07545.1 - 6.6 5.8 7.4 6.6 5.8 4.4 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain Sec62 PF03839.11 EGG07545.1 - 8.5 5.7 8.0 12 5.2 5.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 NPV_P10 PF05531.7 EGG07546.1 - 0.026 14.7 0.3 0.048 13.9 0.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.3 EGG07546.1 - 0.12 12.1 0.2 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF1269 PF06897.7 EGG07547.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) DEAD PF00270.24 EGG07548.1 - 0.00013 21.4 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EGG07548.1 - 0.0015 17.3 0.0 0.0025 16.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1917 PF08939.5 EGG07548.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) AAA_11 PF13086.1 EGG07548.1 - 0.11 12.0 0.2 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF3505 PF12013.3 EGG07551.1 - 4.1e-10 39.8 4.3 4.4e-09 36.5 0.2 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF3505) DEAD PF00270.24 EGG07552.1 - 2.3e-14 53.2 0.0 4.9e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG07552.1 - 8.8e-14 51.1 0.0 1.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EGG07552.1 - 0.033 14.1 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain YfdX PF10938.3 EGG07555.1 - 0.061 12.9 1.0 0.15 11.7 0.1 2.1 2 1 0 2 2 2 0 YfdX protein SNF2_N PF00176.18 EGG07556.1 - 2.7e-08 32.9 0.1 3.6e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.18 EGG07557.1 - 3.8e-08 32.4 0.1 0.0027 16.5 0.0 2.4 1 1 2 3 3 3 2 SNF2 family N-terminal domain Daxx PF03344.10 EGG07560.1 - 0.79 8.1 10.7 0.81 8.0 7.4 1.0 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EGG07560.1 - 6.7 4.5 10.8 6.7 4.4 7.5 1.0 1 0 0 1 1 1 0 Nop14-like family SVWC PF15430.1 EGG07562.1 - 0.0092 16.4 1.1 0.026 14.9 0.7 1.7 1 0 0 1 1 1 1 Single domain von Willebrand factor type C CPSase_L_D2 PF02786.12 EGG07565.1 - 5.6e-22 78.0 0.0 3.5e-19 68.9 0.0 2.1 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EGG07565.1 - 0.0081 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Pkinase PF00069.20 EGG07566.1 - 1e-38 132.9 0.0 8.1e-14 51.3 0.0 3.1 1 1 2 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EGG07566.1 - 4.2e-19 68.6 2.0 5.3e-07 28.9 0.0 3.1 1 1 2 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 EGG07566.1 - 0.12 11.3 1.6 0.93 8.3 1.1 2.6 1 1 0 1 1 1 0 Kinase-like SHR3_chaperone PF08229.6 EGG07567.1 - 0.072 12.0 0.5 0.078 11.9 0.4 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 Spc97_Spc98 PF04130.8 EGG07568.1 - 7.8e-118 394.1 4.0 9.5e-118 393.8 2.8 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DHHA1 PF02272.14 EGG07568.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 DHHA1 domain Ras PF00071.17 EGG07569.1 - 5.2e-17 61.7 0.1 5.6e-17 61.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG07569.1 - 3.6e-06 27.4 0.1 4.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG07569.1 - 2.1e-05 23.8 0.0 2.3e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGG07569.1 - 0.00067 18.8 0.3 0.0012 18.0 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EGG07569.1 - 0.0035 17.5 0.0 0.0035 17.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGG07569.1 - 0.0093 15.9 0.0 0.0093 15.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EGG07569.1 - 0.011 15.2 0.1 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EGG07569.1 - 0.012 14.7 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EGG07569.1 - 0.023 13.9 0.0 0.027 13.6 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 EGG07569.1 - 0.031 13.9 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EGG07569.1 - 0.039 13.6 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM PF00493.18 EGG07569.1 - 0.068 11.9 0.0 0.076 11.8 0.0 1.1 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 EGG07569.1 - 0.079 12.9 0.0 0.1 12.5 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EGG07569.1 - 0.081 13.2 0.0 0.081 13.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EGG07569.1 - 0.088 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Herpes_UL56 PF04534.7 EGG07570.1 - 0.095 12.4 0.1 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein LSM PF01423.17 EGG07571.1 - 1.5e-15 56.4 0.0 2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain Fungal_trans PF04082.13 EGG07572.1 - 2.2e-18 66.1 1.9 4.7e-18 64.9 1.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGG07572.1 - 1.9e-05 24.4 11.0 3.6e-05 23.5 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGAP PF00620.22 EGG07573.1 - 6.2e-43 146.0 0.0 1.3e-42 145.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EGG07573.1 - 3.7e-09 36.7 0.0 1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 PH domain PX PF00787.19 EGG07573.1 - 9.4e-08 31.8 0.0 2e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 PX domain PH_11 PF15413.1 EGG07573.1 - 0.00031 20.9 0.4 0.0018 18.5 0.0 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain Protoglobin PF11563.3 EGG07573.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protoglobin PH_8 PF15409.1 EGG07573.1 - 0.15 12.1 0.0 0.7 10.0 0.0 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain DUF2670 PF10875.3 EGG07574.1 - 0.054 13.5 0.1 0.095 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) DUF3048 PF11258.3 EGG07575.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) Alpha_kinase PF02816.13 EGG07577.1 - 5.3e-05 22.9 0.2 6.7e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 Alpha-kinase family zf-CCHC PF00098.18 EGG07578.1 - 7.6 6.6 12.3 0.18 11.7 1.7 2.4 2 0 0 2 2 2 0 Zinc knuckle Herpes_UL32 PF06070.6 EGG07579.1 - 0.0031 16.0 1.4 0.0035 15.9 0.9 1.0 1 0 0 1 1 1 1 Herpesvirus large structural phosphoprotein UL32 FGGY_C PF02782.11 EGG07580.1 - 1.7e-60 204.0 0.2 3.5e-60 203.0 0.1 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGG07580.1 - 2e-59 200.8 0.0 3.5e-59 200.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain RNA_pol_Rpb1_5 PF04998.12 EGG07581.1 - 6.2e-90 301.2 0.2 1.5e-89 299.9 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EGG07581.1 - 3.7e-81 273.0 0.2 4.8e-80 269.3 0.1 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EGG07581.1 - 4.1e-65 218.7 0.0 8.3e-65 217.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGG07581.1 - 1.6e-38 131.9 0.0 4e-38 130.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EGG07581.1 - 1.7e-30 104.9 0.0 5.2e-30 103.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DUF1178 PF06676.6 EGG07581.1 - 0.21 11.7 0.3 0.44 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Na_Ca_ex PF01699.19 EGG07582.1 - 1e-24 86.7 26.8 1.9e-14 53.4 7.3 4.4 4 1 1 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EGG07582.1 - 2.2e-12 47.1 8.3 2.2e-12 47.1 5.8 4.7 4 0 0 4 4 4 1 Domain of unknown function (DUF307) DUF4379 PF14311.1 EGG07582.1 - 0.052 13.3 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) Zn_Tnp_IS1595 PF12760.2 EGG07582.1 - 0.2 11.4 0.6 0.42 10.4 0.4 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain PRK PF00485.13 EGG07583.1 - 5.7e-11 42.3 0.0 7.8e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EGG07583.1 - 1.7e-06 28.8 0.0 6.5e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG07583.1 - 2.5e-05 24.5 0.2 0.00019 21.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGG07583.1 - 0.00014 22.0 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EGG07583.1 - 0.00044 19.9 0.1 0.00067 19.4 0.1 1.3 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.1 EGG07583.1 - 0.00069 19.6 0.1 0.00078 19.4 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGG07583.1 - 0.0012 18.5 0.2 0.0033 17.1 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain CoaE PF01121.15 EGG07583.1 - 0.0055 16.1 0.2 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_33 PF13671.1 EGG07583.1 - 0.0091 15.8 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EGG07583.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGG07583.1 - 0.013 14.4 0.0 0.025 13.4 0.0 1.4 2 0 0 2 2 2 0 NB-ARC domain ArgK PF03308.11 EGG07583.1 - 0.015 14.1 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_5 PF07728.9 EGG07583.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EGG07583.1 - 0.026 14.1 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 EGG07583.1 - 0.037 13.0 0.0 0.088 11.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 EGG07583.1 - 0.037 14.3 0.1 0.066 13.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.15 EGG07583.1 - 0.037 13.6 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase MobB PF03205.9 EGG07583.1 - 0.046 13.4 0.1 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EGG07583.1 - 0.053 12.6 0.0 0.14 11.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 EGG07583.1 - 0.072 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 EGG07583.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EGG07583.1 - 0.095 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EGG07583.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EGG07583.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.9 EGG07583.1 - 0.13 11.1 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA PF00004.24 EGG07583.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EGG07583.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 Asp PF00026.18 EGG07584.1 - 1.3e-16 60.8 0.0 2.7e-16 59.6 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease 4HB_MCP_1 PF12729.2 EGG07585.1 - 0.026 13.8 0.9 0.026 13.8 0.6 2.6 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction Tropomyosin PF00261.15 EGG07585.1 - 0.074 12.1 8.4 0.091 11.8 3.9 2.2 2 0 0 2 2 2 0 Tropomyosin BMFP PF04380.8 EGG07585.1 - 0.079 13.1 8.2 0.2 11.8 1.1 4.1 1 1 2 3 3 3 0 Membrane fusogenic activity TSC22 PF01166.13 EGG07585.1 - 0.34 10.9 0.1 0.34 10.9 0.1 3.8 4 1 1 5 5 5 0 TSC-22/dip/bun family Reo_sigmaC PF04582.7 EGG07585.1 - 0.95 8.5 11.1 6 5.9 3.4 2.5 1 1 0 2 2 2 0 Reovirus sigma C capsid protein CtIP_N PF10482.4 EGG07585.1 - 1.4 8.7 11.6 1.3 8.8 5.2 2.8 2 2 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain GlutR_dimer PF00745.15 EGG07585.1 - 2.2 8.2 10.1 6.3 6.8 0.3 3.5 2 1 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Prefoldin_2 PF01920.15 EGG07585.1 - 3 7.6 12.0 0.11 12.2 0.9 3.5 3 2 1 4 4 4 0 Prefoldin subunit DUF92 PF01940.11 EGG07586.1 - 2.1e-42 144.8 0.7 5.3e-42 143.5 0.5 1.6 1 1 0 1 1 1 1 Integral membrane protein DUF92 SUR7 PF06687.7 EGG07587.1 - 0.00012 21.7 8.5 0.00024 20.7 5.9 1.6 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EGG07587.1 - 0.0093 15.6 1.2 0.0093 15.6 0.9 2.0 2 1 1 3 3 3 2 PMP-22/EMP/MP20/Claudin tight junction GPI-anchored PF10342.4 EGG07588.1 - 2.7e-10 40.5 0.7 6.1e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 EGG07590.1 - 4.9e-14 52.5 1.6 4.9e-14 52.5 1.1 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pyrid_oxidase_2 PF13883.1 EGG07590.1 - 1.5 8.5 5.1 2.5 7.8 3.5 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase HhH-GPD PF00730.20 EGG07592.1 - 1.4e-12 47.8 0.0 2.3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein CN_hydrolase PF00795.17 EGG07593.1 - 9.7e-24 83.7 0.0 1.6e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Patatin PF01734.17 EGG07594.1 - 8e-11 42.2 0.8 8.9e-11 42.0 0.5 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase DUF1092 PF06485.6 EGG07595.1 - 0.028 13.4 0.1 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) Cript PF10235.4 EGG07596.1 - 0.07 13.4 1.3 0.2 12.0 0.9 1.7 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT TRI9 PF08195.6 EGG07596.1 - 0.15 11.6 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 TRI9 protein VWA_2 PF13519.1 EGG07598.1 - 4.2e-14 53.0 0.0 7.6e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGG07598.1 - 3.2e-06 26.9 0.0 1.2e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain FAM176 PF14851.1 EGG07598.1 - 1.5 8.4 4.6 3.8 7.1 3.2 1.6 1 0 0 1 1 1 0 FAM176 family Transp_cyt_pur PF02133.10 EGG07599.1 - 0.087 11.3 0.1 0.15 10.5 0.1 1.3 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3759 PF12585.3 EGG07602.1 - 7.8e-26 89.8 0.7 9.7e-26 89.5 0.4 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3318 PF11780.3 EGG07602.1 - 0.071 12.6 0.2 0.11 12.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3318) UbiA PF01040.13 EGG07603.1 - 1.1e-23 83.8 19.3 1.4e-23 83.4 13.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3431 PF11913.3 EGG07605.1 - 6.3e-05 22.5 0.0 8.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) LssY_C PF14067.1 EGG07606.1 - 0.022 13.7 0.1 0.055 12.4 0.0 1.7 2 0 0 2 2 2 0 LssY C-terminus Ras PF00071.17 EGG07607.1 - 7.1e-54 181.5 0.0 8.4e-54 181.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG07607.1 - 4.5e-16 59.4 0.0 6.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG07607.1 - 1.5e-09 37.3 0.0 1.9e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGG07607.1 - 0.0034 16.5 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGG07607.1 - 0.026 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EGG07607.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 EGG07607.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGG07607.1 - 0.15 11.5 0.0 0.42 10.1 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sas10 PF09368.5 EGG07609.1 - 1.2e-22 79.8 8.1 1.2e-22 79.8 5.6 2.6 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EGG07609.1 - 0.014 15.5 4.7 0.022 14.9 0.1 3.2 3 0 0 3 3 3 0 Sas10/Utp3/C1D family G-patch PF01585.18 EGG07611.1 - 2e-07 30.7 3.4 2e-07 30.7 2.4 3.2 3 1 0 3 3 3 1 G-patch domain zf-C2H2_jaz PF12171.3 EGG07611.1 - 3.4e-06 27.0 1.9 6.8e-06 26.0 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding G-patch_2 PF12656.2 EGG07611.1 - 3.8e-05 23.4 2.4 3.8e-05 23.4 1.6 2.7 2 0 0 2 2 2 1 DExH-box splicing factor binding site zf-met PF12874.2 EGG07611.1 - 7.5e-05 22.7 0.8 0.00014 21.9 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EGG07611.1 - 0.046 14.0 1.2 0.1 12.9 0.8 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG07611.1 - 0.066 13.5 1.0 0.13 12.6 0.7 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGG07611.1 - 0.2 11.6 1.8 0.32 10.9 1.3 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2868 PF11067.3 EGG07611.1 - 0.24 10.5 0.3 0.34 10.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) EIIBC-GUT_N PF03612.9 EGG07611.1 - 5.5 6.5 8.7 0.98 9.0 0.2 2.8 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Trehalase PF01204.13 EGG07612.1 - 7.2e-97 325.1 0.9 1e-96 324.6 0.6 1.2 1 0 0 1 1 1 1 Trehalase DUF4413 PF14372.1 EGG07612.1 - 0.0012 18.7 0.3 0.092 12.7 0.1 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) Cas_Cas6 PF01881.11 EGG07612.1 - 0.32 11.2 8.4 0.44 10.7 0.9 2.9 3 0 0 3 3 3 0 CRISPR associated protein Cas6 Ycf1 PF05758.7 EGG07613.1 - 0.039 11.7 15.3 0.046 11.4 10.6 1.1 1 0 0 1 1 1 0 Ycf1 Bud13 PF09736.4 EGG07613.1 - 4.2 7.6 23.0 8.3 6.6 16.0 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Zip PF02535.17 EGG07613.1 - 4.4 6.2 9.3 13 4.6 5.6 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter NARP1 PF12569.3 EGG07613.1 - 6 5.5 19.1 8.2 5.0 13.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Paramyxo_ncap PF00973.14 EGG07613.1 - 6.7 5.2 14.1 9.1 4.8 9.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein AvrE PF11725.3 EGG07613.1 - 7.1 3.5 14.6 8.8 3.2 10.1 1.0 1 0 0 1 1 1 0 Pathogenicity factor CRAL_TRIO PF00650.15 EGG07614.1 - 1.7e-18 66.6 0.0 4.2e-18 65.3 0.0 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGG07614.1 - 0.0052 16.8 0.3 0.016 15.3 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF3439 PF11921.3 EGG07614.1 - 1.7 8.3 4.8 3.7 7.3 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CRAL_TRIO PF00650.15 EGG07616.1 - 2.1e-18 66.2 0.0 5.1e-18 65.0 0.0 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGG07616.1 - 0.0061 16.6 0.3 0.018 15.1 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CTK3 PF12243.3 EGG07617.1 - 7.1e-31 106.7 3.6 2.9e-22 78.8 0.2 2.3 2 0 0 2 2 2 2 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EGG07617.1 - 6.5e-13 48.5 0.1 2e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus DEC-1_N PF04625.8 EGG07618.1 - 0.0059 15.3 3.9 0.0093 14.6 2.7 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region TFIIA PF03153.8 EGG07618.1 - 0.56 10.0 9.2 0.83 9.4 6.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2638 PF10937.3 EGG07618.1 - 1.2 10.1 5.6 0.32 12.0 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2638) DUF566 PF04484.7 EGG07618.1 - 6.7 6.1 10.1 11 5.3 7.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF3678 PF12435.3 EGG07622.1 - 1.3 8.5 19.4 0.47 10.0 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) DUF3246 PF11596.3 EGG07623.1 - 0.064 12.5 2.1 0.16 11.2 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Sugar_tr PF00083.19 EGG07623.1 - 0.12 10.9 13.1 0.021 13.4 1.7 2.8 2 1 1 3 3 3 0 Sugar (and other) transporter ATG22 PF11700.3 EGG07623.1 - 1 7.7 17.9 0.04 12.3 4.2 2.7 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like DUF159 PF02586.9 EGG07624.1 - 3.9e-57 193.1 0.1 5.1e-57 192.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Ala_racemase_N PF01168.15 EGG07625.1 - 3.5e-34 118.2 0.0 4e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain RasGEF PF00617.14 EGG07628.1 - 4.9e-52 176.4 0.0 9e-52 175.5 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGG07628.1 - 2.5e-21 75.7 0.0 6.3e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EGG07628.1 - 1.3e-08 34.2 0.0 2.5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGG07628.1 - 4e-07 29.4 0.0 7.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGG07628.1 - 3.1e-05 23.2 0.0 7.1e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SDA1 PF05285.7 EGG07629.1 - 0.0024 17.2 41.7 0.0024 17.2 28.9 1.5 2 0 0 2 2 2 1 SDA1 DUF4045 PF13254.1 EGG07629.1 - 1.8 7.7 18.4 0.96 8.6 8.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) POP1 PF06978.6 EGG07630.1 - 5.9e-44 149.9 22.5 1.6e-41 142.0 15.6 2.6 1 1 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EGG07630.1 - 6.7e-15 54.7 0.3 1.9e-14 53.2 0.2 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.16 EGG07630.1 - 0.038 13.3 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain UBN2_3 PF14244.1 EGG07633.1 - 0.00069 19.2 0.1 0.0077 15.8 0.0 2.1 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGG07633.1 - 0.0017 18.1 0.1 0.0031 17.2 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG07633.1 - 0.0047 16.4 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF3597 PF12200.3 EGG07633.1 - 2.6 8.4 5.1 2.7 8.3 1.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3597) Peroxidase_2 PF01328.12 EGG07634.1 - 0.00059 18.5 0.1 0.0012 17.5 0.0 1.5 1 0 0 1 1 1 1 Peroxidase, family 2 RST PF12174.3 EGG07634.1 - 0.076 12.8 0.0 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain DUF4451 PF14616.1 EGG07636.1 - 1.2e-22 79.9 5.0 5.4e-22 77.8 0.9 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4451) DUF3328 PF11807.3 EGG07637.1 - 0.0022 17.7 0.1 0.0025 17.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DctQ PF04290.7 EGG07637.1 - 0.0056 16.4 0.1 0.0076 16.0 0.1 1.2 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component Vpu PF00558.14 EGG07637.1 - 0.085 12.4 0.2 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Vpu protein Shikimate_dh_N PF08501.6 EGG07639.1 - 6.5e-17 61.3 0.0 1.2e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EGG07639.1 - 7.4e-06 26.1 0.0 3e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TauD PF02668.11 EGG07641.1 - 1.3e-39 136.4 0.1 4.5e-39 134.6 0.0 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAM60A PF15396.1 EGG07644.1 - 0.1 12.3 4.8 0.13 12.0 3.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A IBB PF01749.15 EGG07644.1 - 0.13 12.4 9.4 0.5 10.5 1.6 2.4 1 1 1 2 2 2 0 Importin beta binding domain Opi1 PF08618.5 EGG07644.1 - 3.3 6.5 13.3 4.5 6.0 2.4 2.0 1 1 1 2 2 2 0 Transcription factor Opi1 GCM PF03615.10 EGG07645.1 - 0.85 9.2 5.2 4.4 6.8 3.6 2.1 1 1 0 1 1 1 0 GCM motif protein SCP2 PF02036.12 EGG07647.1 - 3.6e-26 91.4 1.6 4.7e-26 91.0 1.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EGG07647.1 - 0.0073 16.2 0.1 0.0087 16.0 0.1 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal VHP PF02209.14 EGG07647.1 - 0.046 13.4 0.3 0.15 11.7 0.1 2.0 2 0 0 2 2 2 0 Villin headpiece domain Myb_DNA-bind_3 PF12776.2 EGG07648.1 - 1.3e-13 51.4 2.3 3.8e-13 49.8 1.6 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Daxx PF03344.10 EGG07648.1 - 2.2 6.6 32.8 0.34 9.3 16.5 2.1 2 0 0 2 2 2 0 Daxx Family Dynamin_N PF00350.18 EGG07652.1 - 7.7e-18 64.8 0.2 1.7e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EGG07652.1 - 8e-10 38.6 0.0 7.4e-09 35.5 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGG07652.1 - 1.3e-08 34.5 0.2 4.8e-08 32.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGG07652.1 - 1e-05 26.0 1.2 0.0084 16.6 0.0 3.0 2 1 1 3 3 3 2 Miro-like protein cobW PF02492.14 EGG07652.1 - 0.00048 19.6 0.0 0.024 14.0 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EGG07652.1 - 0.011 15.2 0.0 0.027 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.8 EGG07652.1 - 0.055 12.2 0.0 0.099 11.4 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Arf PF00025.16 EGG07652.1 - 0.069 12.3 0.0 1.4 8.1 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AcylCoA_dehyd_C PF12186.3 EGG07653.1 - 0.2 11.5 4.5 5.3 6.9 0.5 2.8 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal APC2 PF08672.6 EGG07653.1 - 0.63 10.3 7.6 0.14 12.4 0.5 3.5 5 0 0 5 5 5 0 Anaphase promoting complex (APC) subunit 2 FliE PF02049.13 EGG07653.1 - 2.3 8.3 7.4 4.7 7.3 2.5 3.0 2 2 0 2 2 2 0 Flagellar hook-basal body complex protein FliE RALF PF05498.6 EGG07654.1 - 3.2e-18 66.3 2.1 3.2e-18 66.3 1.5 1.0 1 0 0 1 1 1 1 Rapid ALkalinization Factor (RALF) Tub_2 PF04525.7 EGG07656.1 - 0.014 14.8 0.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 Tubby C 2 Ribosomal_L10 PF00466.15 EGG07657.1 - 0.00048 20.0 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L10 FAA_hydrolase_N PF09298.6 EGG07657.1 - 0.015 15.3 0.1 0.046 13.7 0.0 1.8 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal ESCRT-II PF05871.7 EGG07658.1 - 3.6e-25 88.5 2.5 1.1e-24 86.9 1.7 1.7 1 1 0 1 1 1 1 ESCRT-II complex subunit PSD3 PF07626.6 EGG07660.1 - 0.032 14.2 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) Arc PF03869.9 EGG07662.1 - 0.083 12.5 0.2 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Arc-like DNA binding domain Glyco_hydro_71 PF03659.9 EGG07663.1 - 1.4e-83 280.4 0.5 1.7e-83 280.2 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DevR PF01905.11 EGG07664.1 - 0.011 14.6 0.1 0.018 13.8 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 Syntaxin-6_N PF09177.6 EGG07664.1 - 0.86 10.0 3.6 1.6 9.2 0.1 2.4 3 0 0 3 3 3 0 Syntaxin 6, N-terminal WD40 PF00400.27 EGG07665.1 - 3.3e-61 201.1 21.2 2.2e-11 43.1 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGG07665.1 - 0.0023 16.1 4.7 0.65 8.0 0.2 3.5 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGG07665.1 - 0.075 11.3 0.0 4.3 5.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Lipase_GDSL PF00657.17 EGG07666.1 - 4.6e-08 33.1 0.0 5.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Plant_NMP1 PF06694.6 EGG07667.1 - 0.021 13.7 0.1 3.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Plant nuclear matrix protein 1 (NMP1) zf-C2H2 PF00096.21 EGG07668.1 - 8.8e-08 32.0 7.6 0.00086 19.5 0.1 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG07668.1 - 3.6e-05 23.7 5.0 0.23 11.8 1.0 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGG07668.1 - 0.00027 21.0 1.7 0.00027 21.0 1.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain DPBB_1 PF03330.13 EGG07670.1 - 0.0002 21.2 0.0 0.0004 20.3 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel RRM_1 PF00076.17 EGG07671.1 - 4.8e-24 83.7 0.0 6.2e-24 83.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG07671.1 - 2e-17 62.9 0.0 2.5e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG07671.1 - 5.6e-12 45.3 0.0 7.6e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGG07671.1 - 0.0035 17.0 0.0 0.0063 16.2 0.0 1.4 1 1 0 1 1 1 1 Limkain b1 RRM_3 PF08777.6 EGG07671.1 - 0.13 12.0 0.1 0.21 11.4 0.1 1.3 1 1 0 1 1 1 0 RNA binding motif RasGAP PF00616.14 EGG07674.1 - 1.6e-52 178.0 0.8 4.3e-52 176.6 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EGG07674.1 - 4.7e-32 110.6 0.8 1.5e-31 109.0 0.1 2.3 2 0 0 2 2 2 1 RasGAP C-terminus DUF972 PF06156.8 EGG07674.1 - 0.27 11.5 11.1 3.2 8.1 1.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF972) TPR_1 PF00515.23 EGG07675.1 - 2.1e-20 71.4 14.5 9.7e-05 21.8 0.0 6.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGG07675.1 - 1.3e-19 69.6 15.9 1e-06 28.2 0.1 5.7 4 1 2 6 6 6 3 TPR repeat TPR_2 PF07719.12 EGG07675.1 - 6.4e-18 63.1 19.1 9.9e-05 21.9 0.0 7.6 8 0 0 8 8 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGG07675.1 - 8.1e-14 50.2 8.2 0.0026 17.4 0.1 6.1 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGG07675.1 - 9.6e-13 48.4 11.7 0.00053 20.5 0.0 6.2 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGG07675.1 - 1.3e-12 47.1 12.7 0.0024 18.3 0.0 7.3 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGG07675.1 - 1.5e-11 43.5 6.4 0.031 14.4 0.1 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGG07675.1 - 1.7e-11 43.8 17.5 1.6e-05 24.7 0.2 5.3 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGG07675.1 - 4.8e-11 42.8 10.2 0.01 16.1 0.4 6.9 4 1 2 7 7 7 3 Tetratricopeptide repeat APC8 PF04049.8 EGG07675.1 - 1.5e-07 31.2 0.0 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_7 PF13176.1 EGG07675.1 - 1.8e-07 30.3 9.3 0.071 12.9 0.0 5.9 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 EGG07675.1 - 3.9e-05 22.8 13.7 0.00034 19.7 5.6 3.5 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGG07675.1 - 0.00012 21.9 3.2 0.36 10.7 0.4 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EGG07675.1 - 0.00014 21.9 5.6 2.8 8.1 0.1 4.8 2 1 3 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EGG07675.1 - 0.0063 16.8 15.3 19 5.9 0.0 7.6 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGG07675.1 - 0.0067 16.7 0.4 16 6.3 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 EGG07675.1 - 0.023 13.4 0.0 3.5 6.2 0.0 2.5 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Prok-TraM PF09228.5 EGG07675.1 - 0.12 12.5 0.4 2.8 8.1 0.1 2.6 1 1 1 2 2 2 0 Prokaryotic Transcriptional repressor TraM TPR_10 PF13374.1 EGG07675.1 - 0.7 9.9 5.7 13 5.8 0.1 4.5 6 0 0 6 6 4 0 Tetratricopeptide repeat Ribosomal_S21 PF01165.15 EGG07679.1 - 1.1e-08 34.3 4.4 1.5e-08 33.9 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S21 MBOAT_2 PF13813.1 EGG07680.1 - 1.8e-13 50.3 0.6 4.1e-13 49.2 0.4 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family zf-DNL PF05180.7 EGG07681.1 - 8.9e-25 86.2 0.9 2.7e-24 84.6 0.6 1.8 1 1 0 1 1 1 1 DNL zinc finger HSP33 PF01430.14 EGG07681.1 - 0.093 11.8 1.1 0.13 11.3 0.6 1.4 2 0 0 2 2 2 0 Hsp33 protein HMG_box PF00505.14 EGG07684.1 - 0.02 15.1 1.6 1.2 9.4 0.1 2.6 2 0 0 2 2 2 0 HMG (high mobility group) box DUF953 PF06110.6 EGG07685.1 - 9.1e-19 67.0 0.0 1.1e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_8 PF13905.1 EGG07685.1 - 0.0059 16.7 0.3 0.014 15.5 0.1 1.6 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EGG07685.1 - 0.042 13.8 0.1 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Alpha_kinase PF02816.13 EGG07686.1 - 9.9e-06 25.3 0.1 1.9e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Alpha-kinase family DUF1027 PF06265.6 EGG07687.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1027) DUF3394 PF11874.3 EGG07688.1 - 0.046 13.2 1.6 0.073 12.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Pantoate_ligase PF02569.10 EGG07689.1 - 7.1e-43 146.3 0.0 8e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase UCH PF00443.24 EGG07690.1 - 1.4e-59 201.4 0.5 2.8e-59 200.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGG07690.1 - 5.7e-24 85.0 12.2 1.9e-19 70.2 0.1 3.0 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Metal_resist PF13801.1 EGG07690.1 - 1.4 8.8 3.4 1.2 9.0 0.8 2.0 2 0 0 2 2 2 0 Heavy-metal resistance Peptidase_C98 PF15499.1 EGG07690.1 - 3.2 6.9 12.2 0.051 12.8 1.3 2.7 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Bromodomain PF00439.20 EGG07692.1 - 3.4e-37 126.2 2.1 8.4e-20 70.4 0.3 2.4 2 0 0 2 2 2 2 Bromodomain RRS1 PF04939.7 EGG07695.1 - 3.1e-53 179.6 2.5 3.1e-53 179.6 1.8 2.2 3 0 0 3 3 3 1 Ribosome biogenesis regulatory protein (RRS1) zf-RING_2 PF13639.1 EGG07696.1 - 0.035 13.9 3.2 0.057 13.2 1.7 1.9 2 0 0 2 2 2 0 Ring finger domain USP8_dimer PF08969.6 EGG07697.1 - 0.04 13.8 1.3 0.11 12.5 0.1 2.3 2 0 0 2 2 2 0 USP8 dimerisation domain Ribosomal_S17e PF00833.13 EGG07699.1 - 0.16 11.7 0.9 23 4.7 0.0 3.0 2 1 1 3 3 3 0 Ribosomal S17 zf-RING_2 PF13639.1 EGG07700.1 - 0.0059 16.4 3.2 0.009 15.8 1.6 1.8 2 0 0 2 2 2 1 Ring finger domain HNF-1_N PF04814.8 EGG07700.1 - 0.022 14.8 1.8 0.03 14.4 0.5 1.7 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus zf-RING_2 PF13639.1 EGG07701.1 - 3e-08 33.3 4.0 6.7e-08 32.2 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGG07701.1 - 5e-06 26.0 1.9 1.1e-05 25.0 1.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG07701.1 - 4.7e-05 23.3 3.1 0.00011 22.1 2.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGG07701.1 - 0.00011 22.2 3.6 0.00027 20.9 2.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EGG07701.1 - 0.00094 18.7 2.9 0.0021 17.6 2.0 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EGG07701.1 - 0.0037 17.0 1.0 0.0064 16.2 0.3 1.9 2 1 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-Apc11 PF12861.2 EGG07701.1 - 0.0078 16.0 2.8 0.02 14.7 1.9 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EGG07701.1 - 0.043 13.4 4.2 0.11 12.1 2.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EGG07701.1 - 0.32 11.0 2.2 1.5 8.9 1.5 2.1 1 1 0 1 1 1 0 RING-variant domain TP6A_N PF04406.9 EGG07702.1 - 0.084 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Type IIB DNA topoisomerase Cpn60_TCP1 PF00118.19 EGG07703.1 - 1.2e-156 522.1 0.8 1.3e-156 522.0 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MBOAT_2 PF13813.1 EGG07704.1 - 5e-12 45.7 0.8 1.2e-11 44.5 0.6 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Glyco_hydro_39 PF01229.12 EGG07704.1 - 0.098 11.0 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 MBOAT_2 PF13813.1 EGG07705.1 - 2.4e-12 46.7 1.6 5.2e-12 45.6 1.1 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.1 EGG07706.1 - 5.1e-07 29.6 0.1 1.1e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Chitin_synth_2 PF03142.10 EGG07707.1 - 5.7e-241 800.4 0.5 7.5e-241 800.1 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EGG07707.1 - 2.2e-130 435.8 0.0 2.8e-130 435.4 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EGG07707.1 - 1.9e-18 65.9 0.0 3.2e-10 39.6 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EGG07707.1 - 1e-17 63.6 0.2 1.1e-16 60.3 0.1 2.5 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EGG07707.1 - 1.1e-14 54.6 5.5 3e-14 53.2 3.8 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGG07707.1 - 2.2e-13 50.5 0.0 7.8e-10 38.9 0.0 3.2 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGG07707.1 - 0.00011 21.9 0.0 0.017 14.8 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGG07707.1 - 0.00064 19.0 0.1 0.0021 17.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 CK_II_beta PF01214.13 EGG07711.1 - 1.5e-73 246.2 0.0 1.8e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF4449 PF14613.1 EGG07712.1 - 3.9e-15 56.1 1.1 3.9e-15 56.1 0.8 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF4449) LMBR1 PF04791.11 EGG07712.1 - 0.025 13.1 4.0 0.054 12.0 2.8 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein Prominin PF05478.6 EGG07712.1 - 3 5.2 6.7 3.6 5.0 0.7 2.4 2 0 0 2 2 2 0 Prominin Ferritin_2 PF13668.1 EGG07713.1 - 1e-45 155.0 0.8 1.4e-45 154.5 0.6 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF1767 PF08585.7 EGG07716.1 - 9e-09 35.4 1.4 2e-08 34.3 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Menin PF05053.8 EGG07716.1 - 0.4 8.7 5.6 0.53 8.3 3.9 1.1 1 0 0 1 1 1 0 Menin RRM_1 PF00076.17 EGG07717.1 - 7.3e-18 63.9 0.0 1e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG07717.1 - 1.8e-13 50.2 0.0 2.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG07717.1 - 8.1e-09 35.2 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.22 EGG07718.1 - 2.6e-36 124.9 0.0 4.9e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGG07718.1 - 3.6e-16 59.4 9.4 5.4e-16 58.8 6.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EGG07718.1 - 4.9e-07 29.1 0.0 8.2e-06 25.2 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGG07718.1 - 2.3e-06 27.8 0.0 0.0012 18.9 0.1 2.3 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGG07718.1 - 1.4e-05 25.1 0.2 5.5e-05 23.2 0.1 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EGG07718.1 - 0.00039 20.5 0.1 0.0026 17.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGG07718.1 - 0.00082 18.8 1.4 0.0011 18.3 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGG07718.1 - 0.0069 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EGG07718.1 - 0.021 14.2 0.1 0.045 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 EGG07718.1 - 0.03 13.4 0.0 0.071 12.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EGG07718.1 - 0.031 13.6 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGG07718.1 - 0.04 14.2 0.1 0.18 12.1 0.0 2.1 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.18 EGG07718.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 EGG07718.1 - 0.048 13.3 0.1 0.32 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.9 EGG07718.1 - 0.065 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EGG07718.1 - 0.074 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 NACHT PF05729.7 EGG07718.1 - 0.078 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SbcCD_C PF13558.1 EGG07718.1 - 0.087 12.7 0.3 0.96 9.4 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EGG07718.1 - 0.1 13.4 0.0 0.25 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain RICTOR_M PF14666.1 EGG07719.1 - 3.3e-65 219.2 2.7 5.9e-64 215.1 0.5 3.5 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 EGG07719.1 - 2.6e-43 148.0 0.3 8.7e-42 143.0 0.2 2.6 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.1 EGG07719.1 - 2.5e-32 111.2 0.0 1.7e-31 108.5 0.0 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EGG07719.1 - 6.5e-27 93.2 2.9 1.1e-25 89.3 0.2 4.1 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.1 EGG07719.1 - 7e-05 23.0 0.1 3.5 7.9 0.0 4.2 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EGG07719.1 - 0.0037 17.7 0.0 64 4.2 0.0 4.2 3 0 0 3 3 3 0 HEAT-like repeat RasGEF_N PF00618.15 EGG07719.1 - 0.0045 17.0 0.2 0.15 12.1 0.0 3.4 3 1 0 3 3 3 1 RasGEF N-terminal motif HEAT PF02985.17 EGG07719.1 - 0.0058 16.6 0.5 26 5.2 0.0 5.6 6 0 0 6 6 6 0 HEAT repeat Ribosomal_L11_N PF03946.9 EGG07720.1 - 3.4e-18 64.8 0.0 5.3e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EGG07720.1 - 4.5e-13 49.1 0.2 7.9e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Colicin PF01024.14 EGG07720.1 - 0.019 14.5 0.1 2.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Colicin pore forming domain DUF1748 PF08520.5 EGG07722.1 - 2.1e-23 81.7 0.1 2.4e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Ribosomal_L22 PF00237.14 EGG07723.1 - 2.2e-29 101.4 0.9 2.4e-29 101.3 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Sugar-bind PF04198.8 EGG07723.1 - 0.034 13.0 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Myb_Cef PF11831.3 EGG07724.1 - 1.5 7.9 12.5 0.24 10.5 4.0 2.1 2 0 0 2 2 2 0 pre-mRNA splicing factor component Nucleoplasmin PF03066.10 EGG07724.1 - 6.4 6.2 14.8 11 5.5 10.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nol1_Nop2_Fmu PF01189.12 EGG07725.1 - 6.3e-35 120.9 0.0 2.5e-31 109.1 0.0 2.6 1 1 2 3 3 3 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EGG07725.1 - 0.034 14.1 0.0 0.081 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S27e PF01667.12 EGG07727.1 - 0.099 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 Terminase_2 PF03592.11 EGG07728.1 - 0.38 11.0 5.3 4.8 7.4 0.8 2.7 2 0 0 2 2 2 0 Terminase small subunit MPP6 PF10175.4 EGG07729.1 - 0.0003 21.1 0.5 0.0039 17.5 0.0 2.7 2 1 0 2 2 2 1 M-phase phosphoprotein 6 F1F0-ATPsyn_F PF10791.4 EGG07730.1 - 4.6e-35 119.7 0.2 5e-35 119.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EGG07730.1 - 0.00029 20.8 0.0 0.00034 20.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f zf-C2H2 PF00096.21 EGG07731.1 - 3.3e-05 23.9 2.8 3.3e-05 23.9 2.0 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG07731.1 - 0.0017 18.5 3.5 0.0017 18.5 2.4 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGG07731.1 - 0.007 16.5 1.6 0.007 16.5 1.1 3.9 3 0 0 3 3 3 1 Zinc-finger double domain CRAL_TRIO PF00650.15 EGG07732.1 - 1.1e-29 102.9 0.0 1.6e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGG07732.1 - 0.011 15.8 3.2 0.016 15.2 0.2 2.8 3 1 0 3 3 3 0 CRAL/TRIO, N-terminal domain DUF2891 PF11199.3 EGG07732.1 - 0.083 11.4 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) Pup_ligase PF03136.10 EGG07734.1 - 0.037 12.6 0.1 0.05 12.2 0.1 1.1 1 0 0 1 1 1 0 Pup-ligase protein Xpo1 PF08389.7 EGG07735.1 - 0.084 12.7 0.0 5.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Exportin 1-like protein Chitin_synth_2 PF03142.10 EGG07736.1 - 4.5e-274 909.7 0.0 5.6e-274 909.4 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EGG07736.1 - 1.6e-16 60.6 0.7 1.6e-16 60.6 0.5 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGG07736.1 - 3.2e-14 53.3 0.0 5.7e-13 49.2 0.0 2.8 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGG07736.1 - 7.7e-05 22.0 0.0 0.068 12.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGG07736.1 - 0.13 11.9 0.0 0.78 9.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 TYA PF01021.14 EGG07737.1 - 0.0074 16.4 2.6 0.015 15.4 1.8 1.5 1 0 0 1 1 1 1 TYA transposon protein LrgB PF04172.11 EGG07738.1 - 4.2e-21 75.0 11.8 3e-20 72.2 6.9 2.2 1 1 1 2 2 2 1 LrgB-like family PsbJ PF01788.12 EGG07738.1 - 0.76 9.3 4.6 0.41 10.2 0.3 2.8 2 0 0 2 2 2 0 PsbJ PAS_11 PF14598.1 EGG07742.1 - 0.0004 20.2 0.0 0.013 15.4 0.0 2.5 2 0 0 2 2 2 1 PAS domain TMEM213 PF15192.1 EGG07742.1 - 0.23 11.4 0.1 0.23 11.4 0.0 2.5 3 1 0 3 3 3 0 TMEM213 family GATA PF00320.22 EGG07743.1 - 3.1e-13 48.8 3.2 3.1e-13 48.8 2.2 1.9 2 0 0 2 2 2 1 GATA zinc finger DUF4449 PF14613.1 EGG07745.1 - 0.0015 18.4 0.0 0.0051 16.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Herpes_UL92 PF03048.9 EGG07745.1 - 0.27 10.7 2.7 0.3 10.6 0.1 2.3 3 0 0 3 3 3 0 UL92 family Oleosin PF01277.12 EGG07746.1 - 0.026 14.1 2.9 0.051 13.1 2.0 1.5 1 0 0 1 1 1 0 Oleosin F-box-like PF12937.2 EGG07747.1 - 0.06 13.0 3.1 0.73 9.6 2.1 2.6 1 1 0 1 1 1 0 F-box-like O-FucT PF10250.4 EGG07749.1 - 1.2e-06 27.8 0.1 0.045 12.8 0.0 2.4 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase zf-C2H2 PF00096.21 EGG07750.1 - 5.4e-08 32.7 16.3 0.00018 21.6 1.4 3.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG07750.1 - 3.3e-06 27.1 13.9 4.4e-06 26.7 4.3 4.6 4 0 0 4 4 4 2 Zinc-finger double domain Auxin_resp PF06507.8 EGG07750.1 - 0.013 15.3 0.1 0.031 14.1 0.1 1.6 1 0 0 1 1 1 0 Auxin response factor zf-C2H2_4 PF13894.1 EGG07750.1 - 0.26 11.7 22.5 0.16 12.3 1.7 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Orn_Arg_deC_N PF02784.11 EGG07751.1 - 2.7e-69 233.1 0.0 3.9e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EGG07751.1 - 1.2e-23 82.9 0.0 2.4e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Methyltransf_28 PF02636.12 EGG07752.1 - 1.6e-64 217.7 0.0 2e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 EGG07752.1 - 0.028 14.8 0.0 0.052 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Git3 PF11710.3 EGG07753.1 - 1e-11 44.7 6.0 1.7e-11 44.1 4.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EGG07753.1 - 2e-06 27.1 0.7 2.7e-06 26.7 0.5 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 EGG07753.1 - 0.0045 16.7 0.2 0.0045 16.7 0.1 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term TPP_enzyme_M PF00205.17 EGG07754.1 - 7e-14 51.7 0.1 7.4e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF1250 PF06855.7 EGG07755.1 - 0.11 12.0 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) POM121 PF15229.1 EGG07756.1 - 0.029 13.7 0.9 0.04 13.3 0.6 1.1 1 0 0 1 1 1 0 POM121 family EnY2 PF10163.4 EGG07758.1 - 8.4e-15 54.4 0.3 1.2e-14 54.0 0.2 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 T5orf172 PF10544.4 EGG07758.1 - 0.067 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 T5orf172 domain DUF4646 PF15496.1 EGG07758.1 - 0.1 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) MinE PF03776.9 EGG07758.1 - 0.15 11.5 0.4 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE Helicase_C_3 PF13625.1 EGG07759.1 - 3.6e-27 94.6 1.7 9.6e-27 93.2 0.6 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG07759.1 - 5.5e-14 52.4 0.8 9.7e-14 51.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGG07759.1 - 4.5e-12 45.6 0.0 1.2e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGG07759.1 - 5.9e-10 38.4 0.1 1.3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SBP_bac_6 PF13343.1 EGG07759.1 - 0.019 14.2 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein AAA_34 PF13872.1 EGG07759.1 - 0.045 12.5 0.1 0.077 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 priB_priC PF07445.7 EGG07762.1 - 0.046 13.1 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Primosomal replication protein priB and priC IncA PF04156.9 EGG07763.1 - 3 7.3 4.4 4.9 6.7 3.0 1.3 1 0 0 1 1 1 0 IncA protein DUF3035 PF11233.3 EGG07764.1 - 0.069 13.2 0.9 0.069 13.2 0.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3035) Cortex-I_coil PF09304.5 EGG07765.1 - 0.00064 19.7 6.7 0.00093 19.2 4.7 1.1 1 0 0 1 1 1 1 Cortexillin I, coiled coil Spc7 PF08317.6 EGG07765.1 - 0.0053 15.4 7.6 0.0069 15.0 5.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein CHASE3 PF05227.8 EGG07765.1 - 0.006 16.2 2.6 0.0091 15.6 1.8 1.4 1 1 0 1 1 1 1 CHASE3 domain BLOC1_2 PF10046.4 EGG07765.1 - 0.0063 16.6 12.0 0.03 14.4 2.7 2.2 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3461 PF11944.3 EGG07765.1 - 0.025 14.4 0.8 0.039 13.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) DUF342 PF03961.8 EGG07765.1 - 0.027 12.8 3.2 0.032 12.6 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 EGG07765.1 - 0.033 13.9 4.9 0.047 13.4 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Hema_stalk PF08720.5 EGG07765.1 - 0.051 13.0 0.5 0.078 12.4 0.3 1.4 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk UPF0118 PF01594.11 EGG07765.1 - 0.055 12.4 1.5 0.077 11.9 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 IncA PF04156.9 EGG07765.1 - 0.058 12.9 6.7 0.083 12.4 4.6 1.2 1 0 0 1 1 1 0 IncA protein YlqD PF11068.3 EGG07765.1 - 0.076 13.0 5.0 0.11 12.5 3.4 1.1 1 0 0 1 1 1 0 YlqD protein DUF3450 PF11932.3 EGG07765.1 - 0.14 11.4 5.2 0.18 11.0 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4094 PF13334.1 EGG07765.1 - 0.25 11.7 2.8 1.9 8.8 1.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) EMP24_GP25L PF01105.19 EGG07765.1 - 0.27 10.9 3.7 0.13 12.0 1.3 1.5 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD V_ATPase_I PF01496.14 EGG07765.1 - 0.28 9.0 3.2 0.33 8.7 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fzo_mitofusin PF04799.8 EGG07765.1 - 0.63 9.4 6.4 0.24 10.7 2.1 1.8 1 1 1 2 2 2 0 fzo-like conserved region YvrJ PF12841.2 EGG07765.1 - 3.8 6.8 5.6 4.1 6.7 0.1 2.8 3 0 0 3 3 3 0 YvrJ protein family UCH PF00443.24 EGG07766.1 - 1.6e-25 89.7 1.2 2.1e-25 89.3 0.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pup PF05639.6 EGG07766.1 - 0.012 16.0 0.2 0.031 14.7 0.2 1.6 1 0 0 1 1 1 0 Pup-like protein AAA_assoc_C PF09821.4 EGG07766.1 - 0.12 12.6 0.4 4.8 7.4 0.2 2.4 2 0 0 2 2 2 0 C-terminal AAA-associated domain DUF4404 PF14357.1 EGG07766.1 - 3.3 8.1 6.0 0.57 10.6 0.8 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) IncA PF04156.9 EGG07766.1 - 9.6 5.7 9.8 20 4.7 0.1 2.2 2 0 0 2 2 2 0 IncA protein RhoGEF PF00621.15 EGG07767.1 - 1.9e-17 63.7 3.8 1.9e-17 63.7 2.6 3.3 3 0 0 3 3 3 1 RhoGEF domain CNH PF00780.17 EGG07767.1 - 4.6e-16 59.0 4.3 3.7e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 CNH domain PH_5 PF15405.1 EGG07767.1 - 2e-09 37.4 0.1 2e-09 37.4 0.1 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain DUF2791 PF10923.3 EGG07767.1 - 0.0078 14.8 0.4 0.014 14.0 0.3 1.3 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) MMS1_N PF10433.4 EGG07768.1 - 7.7e-48 162.8 0.1 1.6e-47 161.7 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EGG07768.1 - 8.8e-43 146.6 0.1 1.3e-41 142.7 0.0 2.7 4 0 0 4 4 4 1 CPSF A subunit region OPT PF03169.10 EGG07769.1 - 8.1e-60 202.9 22.4 2.7e-46 158.2 7.5 2.8 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Fib_alpha PF08702.5 EGG07770.1 - 0.12 12.5 0.1 0.15 12.1 0.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Peptidase_S10 PF00450.17 EGG07771.1 - 1.2e-70 238.7 0.1 2.7e-70 237.6 0.1 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Ras PF00071.17 EGG07772.1 - 1.2e-42 144.9 0.0 1.4e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG07772.1 - 4.2e-17 62.7 0.0 6.4e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EGG07772.1 - 3.1e-05 23.4 0.0 5.4e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EGG07772.1 - 0.00022 20.5 0.0 0.00025 20.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGG07772.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4405 PF14358.1 EGG07774.1 - 0.18 11.9 0.9 7.4 6.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) zf-RING_2 PF13639.1 EGG07780.1 - 3e-07 30.1 0.5 1.1e-06 28.2 0.3 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGG07780.1 - 0.064 13.2 0.7 0.22 11.5 0.5 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGG07781.1 - 2.9e-06 26.9 3.2 8.6e-06 25.4 2.2 1.8 1 0 0 1 1 1 1 Ring finger domain DUF2046 PF09755.4 EGG07781.1 - 0.34 9.7 3.1 0.83 8.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) COPIIcoated_ERV PF07970.7 EGG07782.1 - 4.1e-70 235.8 1.5 5.7e-70 235.3 1.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGG07782.1 - 4.1e-30 103.6 0.0 9.4e-30 102.4 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PDGLE PF13190.1 EGG07782.1 - 1.8 8.2 4.7 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 PDGLE domain FPN1 PF06963.7 EGG07784.1 - 3.1e-108 361.9 13.6 3.6e-108 361.7 9.4 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) CDC27 PF09507.5 EGG07785.1 - 0.0091 15.2 8.1 0.01 15.1 5.6 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 RRM_1 PF00076.17 EGG07788.1 - 2.1e-17 62.4 0.1 3.2e-17 61.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG07788.1 - 3.6e-17 62.1 0.0 5.7e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 EGG07788.1 - 7.5e-15 55.0 0.2 1.3e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_5 PF13893.1 EGG07788.1 - 9.2e-09 35.0 0.1 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OPT PF03169.10 EGG07795.1 - 2.9e-139 465.3 22.8 3.3e-139 465.1 15.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TRIQK PF15168.1 EGG07795.1 - 0.14 12.0 0.9 0.34 10.8 0.1 2.0 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family zf-C2H2_jaz PF12171.3 EGG07796.1 - 0.0019 18.2 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding OTT_1508_deam PF14441.1 EGG07796.1 - 0.06 13.1 0.3 0.19 11.5 0.2 1.8 1 1 0 1 1 1 0 OTT_1508-like deaminase DUF702 PF05142.7 EGG07797.1 - 0.012 15.7 3.9 0.024 14.8 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF4551 PF15087.1 EGG07797.1 - 0.039 12.3 0.5 0.066 11.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Inh PF02974.9 EGG07799.1 - 0.031 13.8 0.0 0.095 12.2 0.0 1.7 2 0 0 2 2 2 0 Protease inhibitor Inh COG6 PF06419.6 EGG07800.1 - 1.4e-131 439.6 0.5 1.6e-131 439.5 0.3 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Miro PF08477.8 EGG07801.1 - 5.4e-33 113.9 0.0 4e-19 69.2 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EGG07801.1 - 1.3e-28 98.5 0.0 2.8e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EGG07801.1 - 2.4e-28 97.2 2.5 5.5e-28 96.0 0.2 2.5 3 0 0 3 3 3 1 EF hand associated Ras PF00071.17 EGG07801.1 - 3.2e-26 91.6 0.0 1.1e-19 70.3 0.0 2.3 2 0 0 2 2 2 2 Ras family Arf PF00025.16 EGG07801.1 - 1.4e-07 30.8 0.1 0.018 14.2 0.0 3.2 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGG07801.1 - 2.5e-07 30.6 0.1 0.0055 16.6 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EGG07801.1 - 6.8e-07 29.6 0.0 0.0071 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGG07801.1 - 1.7e-06 28.1 0.1 0.024 14.7 0.0 3.3 3 1 0 3 3 2 2 AAA domain EF-hand_6 PF13405.1 EGG07801.1 - 4.2e-06 26.1 2.9 0.088 12.7 0.1 3.3 3 0 0 3 3 2 2 EF-hand domain EF-hand_7 PF13499.1 EGG07801.1 - 7e-06 26.0 1.6 0.13 12.4 0.0 3.2 3 1 0 3 3 2 2 EF-hand domain pair Dynamin_N PF00350.18 EGG07801.1 - 2.3e-05 24.2 2.4 0.22 11.3 0.0 3.5 4 0 0 4 4 3 2 Dynamin family AAA_17 PF13207.1 EGG07801.1 - 2.9e-05 24.8 0.2 0.014 16.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain EF-hand_1 PF00036.27 EGG07801.1 - 5.4e-05 22.2 5.9 0.079 12.3 0.3 3.0 3 0 0 3 3 2 2 EF hand GTP_EFTU PF00009.22 EGG07801.1 - 0.0001 21.7 0.1 0.29 10.5 0.0 3.9 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EGG07801.1 - 0.00011 21.6 0.1 0.051 13.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGG07801.1 - 0.00016 20.8 0.0 0.026 13.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 EF-hand_5 PF13202.1 EGG07801.1 - 0.00019 20.6 4.1 0.09 12.1 0.1 2.8 2 0 0 2 2 2 2 EF hand ABC_tran PF00005.22 EGG07801.1 - 0.0003 21.1 0.0 0.15 12.3 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.1 EGG07801.1 - 0.00039 20.3 0.0 0.92 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGG07801.1 - 0.00043 20.4 0.1 0.91 9.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EGG07801.1 - 0.00096 18.8 0.1 0.99 9.1 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EGG07801.1 - 0.0011 18.5 1.4 4.5 6.7 0.1 4.0 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein EF-hand_10 PF14788.1 EGG07801.1 - 0.0014 18.2 2.7 0.016 14.8 0.1 2.4 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.4 EGG07801.1 - 0.0015 18.4 2.0 0.16 11.9 0.0 3.3 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 EGG07801.1 - 0.0021 17.6 2.2 0.32 10.6 0.0 3.0 3 0 0 3 3 2 1 EF-hand domain pair AAA_16 PF13191.1 EGG07801.1 - 0.0034 17.4 0.1 2.8 7.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EGG07801.1 - 0.0035 17.5 0.0 1.7 8.8 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EGG07801.1 - 0.0045 15.9 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EGG07801.1 - 0.0057 16.1 0.0 3.2 7.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_24 PF13479.1 EGG07801.1 - 0.01 15.4 0.0 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EGG07801.1 - 0.011 15.7 0.0 6 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain VirE PF05272.6 EGG07801.1 - 0.013 14.9 0.0 3 7.2 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E Septin PF00735.13 EGG07801.1 - 0.019 13.9 0.0 0.2 10.6 0.0 2.2 2 0 0 2 2 2 0 Septin G-alpha PF00503.15 EGG07801.1 - 0.02 13.5 0.0 3.3 6.2 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit Arch_ATPase PF01637.13 EGG07801.1 - 0.028 14.1 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_32 PF13654.1 EGG07801.1 - 0.047 12.3 0.1 0.39 9.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EGG07801.1 - 0.062 12.7 0.0 6.3 6.2 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 EGG07801.1 - 0.062 13.2 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EGG07801.1 - 0.089 12.2 0.0 15 4.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EGG07801.1 - 0.092 12.2 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 EGG07801.1 - 0.11 11.9 0.0 9.8 5.5 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EGG07801.1 - 0.15 10.9 0.1 9.4 4.9 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.2 EGG07801.1 - 0.15 11.4 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 EGG07801.1 - 0.16 11.5 0.1 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MCM PF00493.18 EGG07801.1 - 0.22 10.2 0.0 0.42 9.3 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family DUF4337 PF14235.1 EGG07802.1 - 0.017 15.0 3.8 0.018 14.8 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Foie-gras_1 PF11817.3 EGG07802.1 - 0.04 13.3 1.4 0.043 13.2 1.0 1.0 1 0 0 1 1 1 0 Foie gras liver health family 1 PcfK PF14058.1 EGG07802.1 - 0.064 13.3 4.8 0.074 13.1 3.3 1.1 1 0 0 1 1 1 0 PcfK-like protein APP_E2 PF12925.2 EGG07802.1 - 0.12 11.9 7.7 0.12 11.8 5.4 1.1 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein FimP PF09766.4 EGG07802.1 - 0.2 10.6 4.3 0.25 10.3 2.9 1.1 1 0 0 1 1 1 0 Fms-interacting protein eIF3_subunit PF08597.5 EGG07802.1 - 0.27 10.7 6.9 0.32 10.5 4.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Peroxin-3 PF04882.7 EGG07802.1 - 0.27 9.8 3.2 0.26 9.9 1.8 1.2 1 1 0 1 1 1 0 Peroxin-3 DUF3818 PF12825.2 EGG07802.1 - 1.1 7.8 3.6 1.3 7.6 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF1764 PF08576.5 EGG07802.1 - 1.7 9.4 6.5 2.2 9.1 4.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Asp-B-Hydro_N PF05279.6 EGG07802.1 - 2.3 8.0 9.8 2.5 7.8 6.8 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Borrelia_P83 PF05262.6 EGG07802.1 - 3.6 5.7 12.0 4 5.5 8.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein RRM_1 PF00076.17 EGG07803.1 - 3.2e-10 39.5 0.0 4.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG07803.1 - 3.3e-09 36.4 0.0 4.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG07803.1 - 2.2e-07 30.7 0.0 3.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGG07803.1 - 0.0018 17.9 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Cyclin_N PF00134.18 EGG07806.1 - 3e-45 152.8 1.8 1.5e-44 150.6 0.6 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGG07806.1 - 5.2e-27 94.1 0.2 1.1e-26 93.0 0.0 1.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain PI31_Prot_C PF08577.6 EGG07807.1 - 1.5e-11 44.7 5.7 1.5e-11 44.7 3.9 2.6 3 0 0 3 3 3 1 PI31 proteasome regulator DUF2360 PF10152.4 EGG07807.1 - 0.038 14.2 0.4 0.052 13.8 0.3 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) PI31_Prot_N PF11566.3 EGG07807.1 - 0.06 12.9 0.1 3.3 7.2 0.0 2.4 1 1 1 2 2 2 0 PI31 proteasome regulator N-terminal Gly-zipper_OmpA PF13436.1 EGG07808.1 - 0.03 13.9 0.1 0.077 12.6 0.1 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain ABA_WDS PF02496.11 EGG07808.1 - 0.042 14.0 0.3 0.069 13.3 0.2 1.3 1 0 0 1 1 1 0 ABA/WDS induced protein Serinc PF03348.10 EGG07809.1 - 7.8e-134 446.5 11.0 9.3e-134 446.3 7.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) SUR7 PF06687.7 EGG07810.1 - 0.0025 17.3 4.3 0.0053 16.3 3.0 1.5 1 1 0 1 1 1 1 SUR7/PalI family zf-C2H2_2 PF12756.2 EGG07812.1 - 0.046 13.8 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) GCC2_GCC3 PF07699.8 EGG07812.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 GCC2 and GCC3 Baculo_PEP_C PF04513.7 EGG07813.1 - 0.0084 15.9 2.0 0.017 14.9 0.9 1.8 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 EGG07813.1 - 0.043 13.3 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain GATA PF00320.22 EGG07814.1 - 9.5e-30 101.6 15.2 2.5e-15 55.4 1.5 2.5 2 0 0 2 2 2 2 GATA zinc finger ArfGap PF01412.13 EGG07814.1 - 0.026 14.2 6.8 0.3 10.8 1.3 2.2 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf DZR PF12773.2 EGG07814.1 - 0.16 11.8 13.4 5.6 6.8 8.2 3.2 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 EGG07814.1 - 0.37 10.4 5.8 0.82 9.3 0.3 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.12 EGG07814.1 - 0.42 10.2 4.2 3.8 7.1 0.1 2.3 2 1 0 2 2 2 0 Domain found in IF2B/IF5 Zn_ribbon_recom PF13408.1 EGG07814.1 - 0.71 10.1 6.8 1 9.6 0.2 2.7 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-B_box PF00643.19 EGG07814.1 - 0.92 9.4 11.7 2.7 7.9 0.1 3.7 3 1 0 3 3 3 0 B-box zinc finger zf-CHY PF05495.7 EGG07814.1 - 4.4 7.5 8.7 3.7 7.7 2.7 2.7 1 1 1 2 2 2 0 CHY zinc finger RRN7 PF11781.3 EGG07814.1 - 7.5 6.1 8.1 23 4.5 0.1 3.0 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Peptidase_S9 PF00326.16 EGG07815.1 - 8.5e-31 106.8 0.0 1.4e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGG07815.1 - 1.8e-09 37.5 0.4 4.6e-09 36.1 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG07815.1 - 2.1e-09 37.5 0.3 4.3e-09 36.5 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGG07815.1 - 8.8e-05 22.1 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EGG07815.1 - 0.00054 19.5 0.1 0.0064 16.0 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 EGG07815.1 - 0.0041 16.5 0.0 0.0077 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.6 EGG07815.1 - 0.033 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S28 PF05577.7 EGG07815.1 - 0.11 10.9 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DLH PF01738.13 EGG07815.1 - 0.15 11.3 0.0 0.67 9.1 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family RRM_1 PF00076.17 EGG07816.1 - 3.9e-13 48.8 0.0 2e-05 24.1 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG07816.1 - 3.4e-06 26.7 0.0 0.00026 20.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG07816.1 - 3.9e-06 26.7 0.0 7e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DoxA PF07680.6 EGG07817.1 - 0.027 14.1 0.6 0.077 12.6 0.2 1.7 1 1 1 2 2 2 0 TQO small subunit DoxA SCP2 PF02036.12 EGG07818.1 - 1.5e-14 54.0 0.0 2.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EGG07818.1 - 0.00032 20.6 0.0 0.00041 20.3 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 EGG07818.1 - 0.13 11.6 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Sterol carrier protein domain BUD22 PF09073.5 EGG07819.1 - 0.25 10.3 2.9 0.31 10.0 2.0 1.1 1 0 0 1 1 1 0 BUD22 Cut8_N PF14482.1 EGG07819.1 - 9.7 6.2 6.9 31 4.6 4.8 2.0 1 1 0 1 1 1 0 Cut8 proteasome-binding domain RXT2_N PF08595.6 EGG07820.1 - 9.6e-05 22.2 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 RXT2-like, N-terminal Myb_DNA-bind_3 PF12776.2 EGG07822.1 - 2.6e-14 53.6 0.5 7.1e-14 52.2 0.4 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGG07822.1 - 1.1e-05 25.4 0.5 0.00012 22.1 0.0 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MRP-L47 PF06984.8 EGG07823.1 - 8.4e-18 64.0 0.1 2.7e-17 62.4 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L1 PF00687.16 EGG07827.1 - 3.9e-52 176.7 0.5 5.6e-52 176.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family GlcNAc_2-epim PF07221.6 EGG07828.1 - 0.056 12.4 0.4 0.067 12.1 0.2 1.3 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) F-box-like PF12937.2 EGG07829.1 - 0.019 14.7 1.4 0.071 12.8 0.9 2.1 1 1 0 1 1 1 0 F-box-like SprA-related PF12118.3 EGG07831.1 - 0.32 10.2 17.8 0.4 9.9 12.3 1.1 1 0 0 1 1 1 0 SprA-related family CAF-1_p150 PF11600.3 EGG07831.1 - 0.9 8.8 15.9 1.1 8.5 11.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CENP-T PF15511.1 EGG07831.1 - 6.1 5.9 31.0 7.5 5.6 21.5 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PCEMA1 PF07418.6 EGG07831.1 - 6.9 5.9 23.4 8.5 5.6 16.2 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Nop14 PF04147.7 EGG07831.1 - 8.6 4.1 33.3 11 3.7 23.1 1.1 1 0 0 1 1 1 0 Nop14-like family AF-4 PF05110.8 EGG07833.1 - 5.7 4.6 26.6 9.6 3.9 18.4 1.3 1 1 0 1 1 1 0 AF-4 proto-oncoprotein DUF3534 PF12053.3 EGG07833.1 - 5.9 6.7 8.6 0.2 11.5 0.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3534) DUF2413 PF10310.4 EGG07835.1 - 0.099 11.4 1.9 0.1 11.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Mucin PF01456.12 EGG07835.1 - 0.59 9.9 13.4 0.12 12.1 6.2 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein PPR_2 PF13041.1 EGG07837.1 - 1e-09 38.2 0.3 0.00077 19.3 0.0 4.5 3 1 2 5 5 5 3 PPR repeat family PPR_1 PF12854.2 EGG07837.1 - 2.8e-07 29.8 0.4 0.54 9.7 0.0 4.3 4 0 0 4 4 4 3 PPR repeat PPR PF01535.15 EGG07837.1 - 0.0021 17.9 4.6 3 8.0 0.0 5.2 5 1 0 5 5 5 1 PPR repeat PPR_3 PF13812.1 EGG07837.1 - 0.0022 18.1 0.6 87 3.7 0.1 5.2 5 1 0 5 5 5 0 Pentatricopeptide repeat domain CDC37_N PF03234.9 EGG07838.1 - 7.9e-32 110.9 6.9 8.2e-32 110.9 4.8 1.0 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding DUF4303 PF14136.1 EGG07838.1 - 0.086 12.4 0.5 0.093 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) PP2C_C PF07830.8 EGG07838.1 - 0.21 11.7 1.7 0.29 11.2 1.0 1.3 1 1 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Ribosomal_L6e PF01159.14 EGG07838.1 - 0.75 10.0 4.0 0.88 9.8 2.8 1.1 1 0 0 1 1 1 0 Ribosomal protein L6e PRP1_N PF06424.7 EGG07838.1 - 1.2 9.4 5.4 1.3 9.3 3.8 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal RR_TM4-6 PF06459.7 EGG07840.1 - 3.7 7.3 9.4 2.4 7.9 5.3 1.6 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tweety PF04906.8 EGG07842.1 - 0.00071 18.1 0.3 0.0011 17.4 0.2 1.2 1 0 0 1 1 1 1 Tweety NPV_P10 PF05531.7 EGG07842.1 - 0.0042 17.3 1.1 0.11 12.7 0.7 2.4 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Tektin PF03148.9 EGG07842.1 - 0.0087 14.6 0.7 0.011 14.2 0.5 1.1 1 0 0 1 1 1 1 Tektin family Baculo_PEP_C PF04513.7 EGG07842.1 - 0.017 14.9 1.5 0.029 14.1 1.1 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 EGG07842.1 - 0.031 12.9 0.3 0.04 12.5 0.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Filament PF00038.16 EGG07842.1 - 0.04 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Intermediate filament protein DUF605 PF04652.11 EGG07845.1 - 1.7 7.9 13.1 2.5 7.3 9.1 1.4 1 0 0 1 1 1 0 Vta1 like RR_TM4-6 PF06459.7 EGG07846.1 - 0.06 13.2 3.1 0.069 13.0 2.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.6 EGG07846.1 - 0.55 10.0 8.7 0.71 9.6 6.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Atg14 PF10186.4 EGG07846.1 - 2.7 6.8 9.9 3.3 6.5 6.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EGG07846.1 - 8.9 5.2 13.0 12 4.8 9.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Acyl-CoA_dh_1 PF00441.19 EGG07847.1 - 0.55 10.3 9.2 0.4 10.7 1.1 2.2 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain FAM60A PF15396.1 EGG07847.1 - 4.8 6.8 9.1 14 5.3 6.3 1.7 1 1 0 1 1 1 0 Protein Family FAM60A TMA7 PF09072.5 EGG07847.1 - 9.5 6.7 11.1 3.7 8.1 5.3 2.1 1 1 1 2 2 2 0 Translation machinery associated TMA7 NAM-associated PF14303.1 EGG07848.1 - 0.0064 16.8 2.7 0.012 15.9 1.9 1.4 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain RP-C PF03428.8 EGG07849.1 - 0.029 13.8 0.9 0.039 13.4 0.6 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Aminotran_1_2 PF00155.16 EGG07850.1 - 5.5e-84 282.2 0.0 6.2e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HpaP PF09483.5 EGG07851.1 - 0.35 10.7 7.6 0.1 12.5 3.4 1.5 1 1 1 2 2 2 0 Type III secretion protein (HpaP) Baculo_PEP_C PF04513.7 EGG07855.1 - 2.1e-05 24.3 0.3 4.1e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF812 PF05667.6 EGG07855.1 - 0.0017 16.9 1.5 0.0017 16.9 1.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF812) AAA_13 PF13166.1 EGG07855.1 - 0.0018 16.8 3.0 0.0029 16.1 2.1 1.3 1 0 0 1 1 1 1 AAA domain Bacillus_HBL PF05791.6 EGG07855.1 - 0.0028 17.0 7.2 0.073 12.4 1.9 2.9 2 1 1 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) FlxA PF14282.1 EGG07855.1 - 0.0058 16.5 1.5 0.0058 16.5 1.0 2.3 2 0 0 2 2 2 1 FlxA-like protein Spc7 PF08317.6 EGG07855.1 - 0.006 15.2 4.6 0.0098 14.5 3.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 EGG07855.1 - 0.014 13.2 3.8 0.019 12.7 2.7 1.1 1 0 0 1 1 1 0 Myosin tail Reo_sigmaC PF04582.7 EGG07855.1 - 0.016 14.3 0.3 0.032 13.3 0.2 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EGG07855.1 - 0.02 14.7 3.7 0.025 14.3 1.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 EGG07855.1 - 0.15 11.9 5.9 0.32 10.8 4.1 1.5 1 0 0 1 1 1 0 Tropomyosin like Laminin_II PF06009.7 EGG07855.1 - 0.21 11.3 4.3 1.1 9.0 0.8 2.6 1 1 1 2 2 2 0 Laminin Domain II Phasin PF05597.6 EGG07855.1 - 0.24 11.1 3.2 0.76 9.5 2.2 1.9 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4618 PF15397.1 EGG07855.1 - 0.25 10.6 4.8 0.43 9.8 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) TMPIT PF07851.8 EGG07855.1 - 0.35 9.8 3.1 0.57 9.2 2.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 EGG07855.1 - 0.41 10.2 5.4 2 7.9 2.7 2.3 1 1 1 2 2 2 0 IncA protein NPV_P10 PF05531.7 EGG07855.1 - 0.48 10.7 3.6 20 5.5 2.5 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.1 EGG07855.1 - 0.92 9.4 6.0 1.9 8.4 3.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TBPIP PF07106.8 EGG07855.1 - 0.98 8.9 8.2 0.55 9.7 3.4 2.2 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 EGG07855.1 - 1 9.4 7.3 1.5 8.8 3.1 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin_2 PF01920.15 EGG07855.1 - 1.3 8.8 7.1 3.7 7.3 1.2 2.9 1 1 2 3 3 3 0 Prefoldin subunit Prefoldin PF02996.12 EGG07855.1 - 1.8 8.1 6.6 13 5.4 0.5 3.1 2 1 0 3 3 3 0 Prefoldin subunit Fzo_mitofusin PF04799.8 EGG07855.1 - 1.9 7.8 5.5 30 3.9 2.0 2.5 1 1 2 3 3 3 0 fzo-like conserved region SlyX PF04102.7 EGG07856.1 - 0.0059 16.9 0.8 0.047 14.0 0.2 2.8 3 0 0 3 3 3 1 SlyX ATG16 PF08614.6 EGG07856.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF780 PF05611.6 EGG07859.1 - 0.011 16.3 3.5 0.02 15.5 2.4 1.3 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) zf-C5HC2 PF02928.11 EGG07859.1 - 0.46 10.5 5.0 0.77 9.8 3.5 1.3 1 0 0 1 1 1 0 C5HC2 zinc finger MFS_1 PF07690.11 EGG07860.1 - 7.1e-13 47.9 47.3 7.9e-07 28.1 10.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.11 EGG07861.1 - 2.1e-07 30.0 46.9 7.9e-07 28.1 20.0 3.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRAP_alpha PF03896.11 EGG07862.1 - 0.33 9.8 3.0 0.25 10.3 0.1 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Ins_P5_2-kin PF06090.7 EGG07863.1 - 0.0051 15.8 0.1 0.0065 15.5 0.1 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase IBR PF01485.16 EGG07864.1 - 0.015 15.1 1.8 0.046 13.5 1.3 1.7 1 1 0 1 1 1 0 IBR domain zf-Di19 PF05605.7 EGG07864.1 - 0.095 12.8 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EGG07864.1 - 0.14 12.5 0.4 0.14 12.5 0.3 2.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-TRAF PF02176.13 EGG07864.1 - 0.22 11.9 0.8 5.3 7.4 0.0 2.0 1 1 0 2 2 2 0 TRAF-type zinc finger IBR PF01485.16 EGG07866.1 - 0.024 14.5 2.0 0.094 12.6 1.4 1.8 1 1 0 1 1 1 0 IBR domain zf-H2C2_2 PF13465.1 EGG07866.1 - 0.13 12.5 0.4 0.13 12.5 0.3 2.7 3 0 0 3 3 3 0 Zinc-finger double domain DUF3583 PF12126.3 EGG07866.1 - 2.2 7.2 4.4 3.4 6.6 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Snf7 PF03357.16 EGG07867.1 - 4.5e-39 133.5 23.7 5.9e-39 133.1 16.4 1.1 1 0 0 1 1 1 1 Snf7 Thioredoxin_7 PF13899.1 EGG07867.1 - 0.082 12.9 0.2 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like CDC37_N PF03234.9 EGG07867.1 - 0.19 12.0 11.0 0.93 9.7 0.8 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding TPR_MLP1_2 PF07926.7 EGG07867.1 - 0.4 10.4 12.3 0.9 9.2 8.5 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4337 PF14235.1 EGG07867.1 - 1.1 9.0 6.8 7 6.4 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) P5CR_dimer PF14748.1 EGG07869.1 - 5.5e-38 129.2 3.6 8e-37 125.5 1.2 2.3 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EGG07869.1 - 1.3e-11 44.7 0.2 1.8e-08 34.6 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EGG07869.1 - 0.21 11.0 1.8 0.94 8.9 0.0 2.3 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA AMP-binding PF00501.23 EGG07870.1 - 1.1e-18 66.8 0.0 1.3e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme HMD PF03201.11 EGG07870.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase GBP_PSP PF02425.10 EGG07870.1 - 0.047 13.2 1.5 0.083 12.4 0.1 2.1 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide NAD_binding_6 PF08030.7 EGG07872.1 - 2.4e-25 89.2 0.0 4.1e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGG07872.1 - 2.6e-20 72.2 0.0 5.3e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGG07872.1 - 2.1e-07 31.0 5.4 3.9e-07 30.1 3.8 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGG07872.1 - 0.0004 20.4 0.0 0.0013 18.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGG07872.1 - 0.016 15.8 0.0 0.58 10.7 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain 2TM PF13239.1 EGG07872.1 - 0.053 13.5 0.3 0.053 13.5 0.2 1.8 2 0 0 2 2 2 0 2TM domain Borrelia_P83 PF05262.6 EGG07874.1 - 1.6 6.8 23.6 2.2 6.4 16.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF572 PF04502.8 EGG07874.1 - 2.9 7.0 19.8 3.8 6.6 13.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PLRV_ORF5 PF01690.12 EGG07874.1 - 8.3 5.4 11.3 12 4.9 7.8 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Daxx PF03344.10 EGG07876.1 - 0.09 11.2 11.4 0.1 11.0 7.9 1.1 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 EGG07876.1 - 0.094 11.9 7.1 0.11 11.6 4.9 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4647 PF15504.1 EGG07876.1 - 0.3 9.8 6.7 0.36 9.6 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Ycf1 PF05758.7 EGG07876.1 - 1.2 6.7 4.7 1.4 6.5 3.2 1.1 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 EGG07876.1 - 5.5 4.5 8.2 6.6 4.2 5.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spc7 PF08317.6 EGG07877.1 - 0.0061 15.2 3.9 0.0061 15.2 2.7 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein Filament PF00038.16 EGG07877.1 - 0.0098 15.3 1.7 0.0098 15.3 1.2 2.2 3 0 0 3 3 3 1 Intermediate filament protein Sec8_exocyst PF04048.9 EGG07877.1 - 0.024 14.2 0.7 0.066 12.8 0.5 1.8 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.7 EGG07877.1 - 0.052 13.3 1.1 0.12 12.1 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG6 PF04111.7 EGG07877.1 - 0.29 10.1 7.4 0.19 10.7 1.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 EGG07877.1 - 2.9 8.2 6.7 0.44 10.9 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF972) GAS PF13851.1 EGG07877.1 - 4.8 6.3 11.4 0.91 8.6 2.3 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Cep57_MT_bd PF06657.8 EGG07881.1 - 7.7e-08 32.1 2.0 7.7e-08 32.1 1.4 3.2 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.7 EGG07881.1 - 0.14 11.9 3.6 0.14 12.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SET PF00856.23 EGG07883.1 - 1.3e-23 84.0 0.2 4.2e-23 82.4 0.1 1.8 1 1 0 1 1 1 1 SET domain N-SET PF11764.3 EGG07883.1 - 0.032 14.1 0.5 0.049 13.5 0.4 1.3 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N MSC PF09402.5 EGG07885.1 - 2.3e-11 42.9 0.3 3.2e-11 42.5 0.2 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Cu-oxidase_3 PF07732.10 EGG07886.1 - 3.4e-44 149.3 0.9 1.1e-41 141.3 0.1 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG07886.1 - 5e-34 116.7 1.5 6e-27 93.8 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EGG07886.1 - 1.9e-24 86.3 0.0 2.4e-23 82.7 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase CHZ PF09649.5 EGG07888.1 - 0.87 8.8 5.7 0.72 9.1 1.4 2.3 2 0 0 2 2 2 0 Histone chaperone domain CHZ Collagen PF01391.13 EGG07890.1 - 2.6e-15 55.6 52.7 5.8e-10 38.5 15.5 4.3 2 1 2 4 4 4 2 Collagen triple helix repeat (20 copies) F-box-like PF12937.2 EGG07891.1 - 0.00024 20.7 1.7 0.00054 19.6 1.2 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EGG07891.1 - 0.0056 16.6 9.1 6.6 7.1 0.0 6.0 4 1 1 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.2 EGG07891.1 - 0.031 13.9 0.0 0.031 13.9 0.0 5.7 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) Pex14_N PF04695.8 EGG07891.1 - 1.8 8.6 10.9 0.18 11.8 2.8 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PP2C PF00481.16 EGG07893.1 - 1.2e-26 93.6 0.0 5.9e-23 81.5 0.0 2.5 2 1 1 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGG07893.1 - 0.034 13.5 0.0 0.22 10.9 0.0 2.2 1 1 1 2 2 2 0 Protein phosphatase 2C SR-25 PF10500.4 EGG07893.1 - 2.1 7.7 15.9 4.2 6.7 11.1 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LSM PF01423.17 EGG07894.1 - 2.8e-18 65.2 0.2 3.3e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain DMRL_synthase PF00885.14 EGG07895.1 - 8.2e-42 142.2 0.0 1e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase YmzC PF14157.1 EGG07897.1 - 0.05 13.4 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 YmzC-like protein GTP_EFTU PF00009.22 EGG07898.1 - 1.3e-48 164.9 0.0 2.2e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EGG07898.1 - 4.9e-13 48.7 0.0 1.6e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EGG07898.1 - 2.3e-08 33.7 0.1 5.9e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EGG07898.1 - 3.4e-05 23.8 0.1 0.00011 22.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EGG07898.1 - 4.8e-05 22.9 0.0 0.0067 15.9 0.0 2.7 1 1 0 2 2 2 1 Elongation factor G, domain IV LpxB PF02684.10 EGG07901.1 - 0.016 13.8 0.1 0.022 13.3 0.1 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase E1-E2_ATPase PF00122.15 EGG07902.1 - 1.1e-20 73.6 0.0 2.2e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EGG07902.1 - 2.1e-19 70.4 0.1 6e-19 68.9 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGG07902.1 - 3.4e-17 63.5 0.1 3e-16 60.4 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGG07902.1 - 9.6e-15 54.3 0.1 5.9e-14 51.8 0.0 2.4 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGG07902.1 - 0.00012 21.7 0.2 0.0015 18.1 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ABC_tran PF00005.22 EGG07903.1 - 3.5e-42 143.9 0.0 6.7e-20 71.7 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EGG07903.1 - 4.1e-20 71.4 4.1 4.1e-20 71.4 2.8 2.5 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 EGG07903.1 - 3.7e-19 69.7 2.7 8.3e-05 22.6 0.0 4.5 3 1 1 4 4 4 4 AAA domain AAA_17 PF13207.1 EGG07903.1 - 1.6e-08 35.4 0.9 0.011 16.5 0.0 3.1 3 1 0 3 3 2 2 AAA domain SMC_N PF02463.14 EGG07903.1 - 5e-08 32.4 3.3 0.56 9.4 0.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGG07903.1 - 5.8e-08 33.3 7.5 0.011 16.1 0.0 4.4 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.1 EGG07903.1 - 1.7e-07 30.6 0.1 0.0041 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EGG07903.1 - 1.4e-06 28.7 0.0 0.042 14.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 EGG07903.1 - 1.5e-06 28.5 0.1 0.064 13.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EGG07903.1 - 2.8e-06 26.6 0.0 0.00075 18.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGG07903.1 - 4.8e-06 26.7 3.0 0.017 15.2 0.0 3.8 5 1 0 5 5 2 2 AAA domain NACHT PF05729.7 EGG07903.1 - 5.1e-06 26.2 0.2 0.031 13.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 EGG07903.1 - 5.1e-06 25.7 10.8 0.17 10.9 0.0 4.9 4 1 1 5 5 5 3 AAA ATPase domain AAA_16 PF13191.1 EGG07903.1 - 3e-05 24.1 0.5 0.064 13.2 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EGG07903.1 - 5e-05 23.2 0.3 0.024 14.5 0.1 3.1 3 1 0 3 3 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EGG07903.1 - 7.3e-05 22.3 0.0 0.39 10.1 0.0 2.9 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 EGG07903.1 - 0.0001 21.7 0.0 1 8.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 EGG07903.1 - 0.00013 21.6 1.2 0.35 10.5 0.0 3.5 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EGG07903.1 - 0.00025 21.0 0.0 0.98 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EGG07903.1 - 0.00031 20.2 0.1 0.64 9.4 0.1 2.9 3 0 0 3 3 3 2 AAA-like domain RNA_helicase PF00910.17 EGG07903.1 - 0.00032 20.8 2.9 4 7.6 0.0 3.8 3 0 0 3 3 3 0 RNA helicase DUF87 PF01935.12 EGG07903.1 - 0.00065 19.5 6.3 1 9.1 0.0 4.2 3 1 1 4 4 4 1 Domain of unknown function DUF87 Septin PF00735.13 EGG07903.1 - 0.0014 17.6 0.7 2.6 6.9 0.0 3.2 3 0 0 3 3 3 2 Septin Dynamin_N PF00350.18 EGG07903.1 - 0.0015 18.4 4.8 0.35 10.6 0.2 3.4 2 1 1 3 3 3 2 Dynamin family AAA_14 PF13173.1 EGG07903.1 - 0.002 18.0 0.0 14 5.6 0.0 4.0 4 0 0 4 4 4 0 AAA domain cobW PF02492.14 EGG07903.1 - 0.0026 17.2 0.5 0.34 10.3 0.0 3.0 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 EGG07903.1 - 0.0034 17.2 2.0 0.46 10.4 0.0 3.1 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.1 EGG07903.1 - 0.004 16.7 0.0 3.6 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EGG07903.1 - 0.0041 17.3 1.0 4.3 7.5 0.0 3.8 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGG07903.1 - 0.0052 16.6 0.2 1.6 8.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.1 EGG07903.1 - 0.0061 16.1 0.0 2 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGG07903.1 - 0.0081 15.8 0.3 4 7.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EGG07903.1 - 0.0084 15.0 0.1 1.1 8.1 0.0 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein ATP-synt_ab PF00006.20 EGG07903.1 - 0.0094 15.4 2.1 0.24 10.8 0.0 2.8 3 1 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 EGG07903.1 - 0.01 15.3 4.2 1.6 8.1 0.0 3.4 4 1 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 EGG07903.1 - 0.014 14.4 0.3 1.8 7.5 0.0 2.7 2 1 0 2 2 2 0 KAP family P-loop domain SRP54 PF00448.17 EGG07903.1 - 0.025 14.0 1.5 2 7.8 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 EGG07903.1 - 0.026 13.3 0.0 5.3 5.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 EGG07903.1 - 0.027 14.1 1.9 4.5 6.9 0.1 3.2 4 0 0 4 4 3 0 NTPase FeoB_N PF02421.13 EGG07903.1 - 0.036 13.3 0.0 1 8.6 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B KaiC PF06745.8 EGG07903.1 - 0.043 12.9 0.3 4.4 6.3 0.0 2.9 3 0 0 3 3 3 0 KaiC ATP_bind_1 PF03029.12 EGG07903.1 - 0.043 13.3 0.0 1.3 8.4 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.7 EGG07903.1 - 0.091 12.0 6.5 0.84 8.8 0.0 3.2 3 1 0 3 3 3 0 Poxvirus A32 protein AAA_19 PF13245.1 EGG07903.1 - 0.11 12.2 0.0 7.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain DivIC PF04977.10 EGG07903.1 - 0.35 10.3 9.2 3.5 7.1 1.1 2.6 2 0 0 2 2 2 0 Septum formation initiator ABC_membrane PF00664.18 EGG07904.1 - 1.5e-40 139.3 3.5 2.1e-40 138.8 2.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGG07904.1 - 1.8e-31 109.2 0.0 3.3e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EGG07904.1 - 2e-05 23.9 0.8 0.0013 17.9 0.1 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EGG07904.1 - 3.4e-05 23.9 0.1 0.0002 21.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EGG07904.1 - 5.6e-05 23.2 0.1 0.25 11.2 0.1 2.3 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGG07904.1 - 0.0034 17.3 0.6 0.011 15.7 0.4 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGG07904.1 - 0.0037 18.0 0.0 0.009 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGG07904.1 - 0.004 16.6 0.2 0.011 15.2 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EGG07904.1 - 0.0069 15.8 0.0 0.087 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGG07904.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EGG07904.1 - 0.017 14.0 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.12 EGG07904.1 - 0.02 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 ABC_ATPase PF09818.4 EGG07904.1 - 0.023 13.3 0.4 0.055 12.0 0.0 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF258 PF03193.11 EGG07904.1 - 0.033 13.3 0.0 0.07 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EGG07904.1 - 0.043 13.2 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EGG07904.1 - 0.076 12.1 0.0 0.19 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DEAD PF00270.24 EGG07904.1 - 0.12 11.8 0.0 5.5 6.4 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase Clat_adaptor_s PF01217.15 EGG07905.1 - 1.7e-05 24.6 0.0 2.1e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Carn_acyltransf PF00755.15 EGG07909.1 - 4.5e-165 550.1 0.0 5.2e-165 549.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Mito_carr PF00153.22 EGG07911.1 - 2.5e-56 187.3 1.1 7.4e-19 67.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2361 PF10153.4 EGG07912.1 - 2.1e-24 85.8 14.0 2.1e-24 85.8 9.7 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) SpoIISA_toxin PF14171.1 EGG07912.1 - 0.079 12.1 1.0 0.13 11.5 0.3 1.5 1 1 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Cas_CT1975 PF09344.5 EGG07912.1 - 0.27 10.5 6.1 0.46 9.7 4.3 1.3 1 0 0 1 1 1 0 CT1975-like protein JAB PF01398.16 EGG07914.1 - 2.7e-14 52.8 0.0 4.7e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGG07914.1 - 3.2e-12 46.5 2.3 6.8e-12 45.4 1.6 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF3432 PF11914.3 EGG07914.1 - 0.093 12.7 1.7 0.27 11.2 1.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) SR-25 PF10500.4 EGG07915.1 - 0.01 15.3 22.0 0.026 13.9 15.3 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bcl-2 PF00452.14 EGG07915.1 - 0.086 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family Cwf_Cwc_15 PF04889.7 EGG07915.1 - 0.29 10.8 10.6 0.5 10.0 7.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF755 PF05501.6 EGG07915.1 - 0.31 11.0 29.9 0.95 9.5 20.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Macoilin PF09726.4 EGG07915.1 - 1.6 6.9 9.4 2.2 6.4 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein tRNA_synt_1c_R2 PF04557.10 EGG07915.1 - 5 7.8 6.4 13 6.5 4.4 1.7 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Consortin_C PF15281.1 EGG07916.1 - 0.1 12.0 0.0 0.29 10.6 0.0 1.8 1 1 0 1 1 1 0 Consortin C-terminus Rhabdo_ncap PF00945.13 EGG07916.1 - 1.1 7.7 6.4 1.6 7.2 4.4 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF2670 PF10875.3 EGG07917.1 - 0.016 15.2 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) DUF4050 PF13259.1 EGG07917.1 - 0.057 13.3 0.4 0.57 10.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4050) zf-U11-48K PF05253.7 EGG07919.1 - 1.7 8.4 3.7 7.8 6.3 0.5 2.5 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger Peptidase_C14 PF00656.17 EGG07920.1 - 1e-68 231.7 0.0 1.2e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Ribosomal_S17 PF00366.15 EGG07921.1 - 4.3e-29 100.3 1.0 6.5e-29 99.7 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 IMS_HHH PF11798.3 EGG07922.1 - 0.0044 16.9 0.0 82 3.5 0.0 4.7 5 0 0 5 5 5 2 IMS family HHH motif Sugar_tr PF00083.19 EGG07923.1 - 6.2e-110 367.8 25.0 7e-110 367.6 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG07923.1 - 2.6e-27 95.4 30.5 2.6e-27 95.4 21.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Cobl PF09469.5 EGG07924.1 - 0.21 11.5 1.1 14 5.7 0.1 2.1 1 1 1 2 2 2 0 Cordon-bleu ubiquitin-like domain WD40 PF00400.27 EGG07925.1 - 1.4e-54 180.1 17.0 4.3e-10 39.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EGG07925.1 - 4.9e-06 26.3 0.0 0.00096 18.9 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EGG07925.1 - 0.00023 20.7 0.1 0.28 10.6 0.0 3.1 2 1 1 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.11 EGG07925.1 - 0.0015 16.9 0.0 0.0028 16.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Gmad1 PF10647.4 EGG07925.1 - 0.0024 17.3 0.4 0.23 10.7 0.0 2.9 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.1 EGG07925.1 - 0.0053 16.9 1.8 0.51 10.6 0.0 4.1 4 1 1 5 5 5 1 PQQ-like domain Nup160 PF11715.3 EGG07925.1 - 0.029 12.5 1.7 3 5.8 0.0 2.9 1 1 1 3 3 3 0 Nucleoporin Nup120/160 Abhydrolase_6 PF12697.2 EGG07928.1 - 2.4e-11 43.9 0.0 4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG07928.1 - 0.03 13.8 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short PF00106.20 EGG07930.1 - 2.5e-24 86.0 1.6 5.7e-10 39.3 0.0 3.1 3 0 0 3 3 3 3 short chain dehydrogenase KR PF08659.5 EGG07930.1 - 2.5e-09 37.0 1.2 0.00036 20.2 0.0 3.1 3 0 0 3 3 3 2 KR domain adh_short_C2 PF13561.1 EGG07930.1 - 1.2e-08 35.0 0.5 6e-05 22.9 0.1 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 EGG07930.1 - 0.00085 18.3 0.1 0.0055 15.6 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Abhydrolase_6 PF12697.2 EGG07931.1 - 7.8e-12 45.5 1.4 1.4e-11 44.7 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG07931.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Exonuc_VII_S PF02609.11 EGG07932.1 - 0.029 14.1 1.8 0.038 13.7 0.1 2.0 3 0 0 3 3 3 0 Exonuclease VII small subunit CotJB PF12652.2 EGG07932.1 - 0.084 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 CotJB protein CorA PF01544.13 EGG07932.1 - 0.094 11.7 0.4 0.46 9.4 0.0 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Shisa PF13908.1 EGG07932.1 - 0.16 12.1 2.3 0.43 10.7 0.1 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Med17 PF10156.4 EGG07933.1 - 4e-23 81.4 0.0 5.5e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PBP1_TM PF14812.1 EGG07934.1 - 0.055 13.7 0.8 0.069 13.4 0.5 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HhH-GPD PF00730.20 EGG07935.1 - 1.3e-15 57.6 0.0 2e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein BAG PF02179.11 EGG07935.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 BAG domain CTP_transf_1 PF01148.15 EGG07937.1 - 4.5e-06 26.5 3.3 5.6e-06 26.2 2.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family L_HGMIC_fpl PF10242.4 EGG07937.1 - 0.0051 16.8 0.2 0.0066 16.4 0.2 1.1 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Gemini_mov PF01708.11 EGG07937.1 - 0.017 14.6 0.1 0.036 13.6 0.1 1.6 1 0 0 1 1 1 0 Geminivirus putative movement protein UPF0233 PF06781.7 EGG07937.1 - 0.12 12.0 2.3 0.31 10.6 1.6 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0233) Flavoprotein PF02441.14 EGG07938.1 - 1.1e-40 138.2 0.0 2e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein DWNN PF08783.6 EGG07942.1 - 3.4e-31 106.9 0.1 8e-31 105.8 0.0 1.7 1 0 0 1 1 1 1 DWNN domain zf-C3HC4_2 PF13923.1 EGG07942.1 - 0.00012 22.0 14.3 0.00012 22.0 9.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG07942.1 - 0.00073 19.1 15.0 0.0016 18.0 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_2 PF13696.1 EGG07942.1 - 0.00078 18.8 3.4 0.00078 18.8 2.3 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-RING_2 PF13639.1 EGG07942.1 - 0.0026 17.5 12.2 0.0026 17.5 8.5 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 EGG07942.1 - 0.014 15.1 7.5 0.031 14.0 5.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-CCHC PF00098.18 EGG07942.1 - 0.024 14.5 3.0 0.035 14.0 0.8 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 EGG07942.1 - 0.052 13.2 1.5 0.1 12.3 0.1 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4_3 PF13920.1 EGG07942.1 - 0.24 11.1 16.6 0.019 14.6 7.9 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGG07942.1 - 0.55 10.1 13.3 1.2 9.0 9.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1712 PF08217.6 EGG07944.1 - 2.2e-10 39.4 0.0 4.3e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) SAM_2 PF07647.12 EGG07946.1 - 0.078 12.8 0.2 14 5.6 0.0 2.5 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) UPF0227 PF05728.7 EGG07948.1 - 0.0082 15.8 0.4 0.016 14.9 0.3 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF1660 PF07874.6 EGG07948.1 - 0.062 13.5 0.3 0.21 11.8 0.2 1.9 1 0 0 1 1 1 0 Prophage protein (DUF1660) Ssl1 PF04056.9 EGG07949.1 - 5.2e-76 254.5 0.1 8.8e-76 253.7 0.0 1.4 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EGG07949.1 - 2.3e-09 37.1 12.4 2.3e-09 37.1 8.6 2.6 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EGG07949.1 - 3.9e-09 36.8 0.0 7.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Mucin PF01456.12 EGG07949.1 - 0.65 9.7 25.9 0.33 10.7 4.6 2.8 3 0 0 3 3 3 0 Mucin-like glycoprotein Dicty_REP PF05086.7 EGG07949.1 - 1.3 6.6 13.0 0.5 8.0 1.1 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Zn_Tnp_IS1595 PF12760.2 EGG07949.1 - 2.5 7.9 12.4 5.2 6.9 2.6 3.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-FPG_IleRS PF06827.9 EGG07949.1 - 5.7 6.6 14.0 0.51 10.0 0.2 3.7 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Na_H_Exchanger PF00999.16 EGG07951.1 - 1.9e-63 214.2 51.3 2.8e-63 213.7 35.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Oxidored_q2 PF00420.19 EGG07951.1 - 0.031 13.8 0.1 0.031 13.8 0.1 3.6 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Exo_endo_phos PF03372.18 EGG07952.1 - 8.6e-14 52.0 0.0 1.4e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NPV_P10 PF05531.7 EGG07956.1 - 0.0096 16.1 0.1 0.023 14.9 0.1 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DNA_pol_E_B PF04042.11 EGG07957.1 - 5.3e-37 127.1 0.5 7.7e-37 126.5 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Lipase_GDSL PF00657.17 EGG07961.1 - 1.9e-06 27.8 4.3 3.8e-05 23.6 3.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Flagellin_N PF00669.15 EGG07961.1 - 0.023 14.4 0.3 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region 2OG-FeII_Oxy_2 PF13532.1 EGG07962.1 - 5e-14 52.5 0.1 5.8e-14 52.3 0.1 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGG07962.1 - 1e-05 25.7 0.0 1.2e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prothymosin PF03247.9 EGG07963.1 - 0.015 15.4 19.7 0.027 14.6 13.7 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Nop14 PF04147.7 EGG07963.1 - 0.015 13.2 17.3 0.025 12.5 12.0 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EGG07963.1 - 0.098 11.1 12.9 0.16 10.4 8.9 1.3 1 0 0 1 1 1 0 Daxx Family DUF2645 PF10840.3 EGG07963.1 - 0.11 12.6 1.8 0.17 12.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2645) SDA1 PF05285.7 EGG07963.1 - 0.19 10.9 12.4 0.3 10.3 8.6 1.2 1 0 0 1 1 1 0 SDA1 DUF4163 PF13739.1 EGG07963.1 - 1.3 9.8 5.6 1.4 9.7 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) CDC45 PF02724.9 EGG07963.1 - 9.4 4.1 12.2 14 3.5 8.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RhoGAP PF00620.22 EGG07964.1 - 4.1e-38 130.3 0.0 8.8e-38 129.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Pkinase PF00069.20 EGG07965.1 - 1.6e-47 161.8 0.0 1.4e-29 103.0 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGG07965.1 - 7.7e-19 67.7 0.0 4.6e-18 65.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG07965.1 - 3.5e-06 26.9 0.0 9.1e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGG07965.1 - 8.5e-05 21.6 0.0 0.00093 18.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like He_PIG PF05345.7 EGG07966.1 - 1.4e-07 31.4 26.3 9.9e-06 25.4 0.4 5.6 6 0 0 6 6 6 3 Putative Ig domain GPI2 PF06432.6 EGG07967.1 - 7e-48 163.3 6.2 9.4e-30 103.9 1.3 2.0 1 1 1 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4077 PF13295.1 EGG07967.1 - 0.0034 17.1 0.0 0.0087 15.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4077) Coatomer_WDAD PF04053.9 EGG07968.1 - 5.5e-159 529.6 0.0 1.1e-158 528.7 0.0 1.4 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EGG07968.1 - 3.5e-51 169.3 7.7 3.7e-10 39.2 0.1 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Isochorismatase PF00857.15 EGG07969.1 - 2.1e-21 76.6 0.0 3.7e-21 75.8 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family Helicase_C PF00271.26 EGG07973.1 - 5e-14 51.9 0.0 1e-13 50.9 0.0 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Abhydrolase_6 PF12697.2 EGG07974.1 - 0.0049 16.7 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGG07974.1 - 0.0058 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGG07974.1 - 0.0084 15.8 0.5 0.018 14.7 0.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EGG07974.1 - 0.088 12.0 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ras PF00071.17 EGG07976.1 - 2e-49 167.0 0.0 2.3e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG07976.1 - 8.6e-15 55.2 0.0 1.3e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG07976.1 - 6.4e-09 35.2 0.0 9e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGG07976.1 - 0.00023 20.3 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 EGG07976.1 - 0.031 13.5 0.1 0.05 12.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 EGG07976.1 - 0.048 12.3 0.9 1.6 7.3 0.1 2.5 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 EGG07976.1 - 0.052 13.6 0.1 0.12 12.5 0.1 1.7 1 1 1 2 2 2 0 AAA domain DAP3 PF10236.4 EGG07976.1 - 0.053 12.4 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 STAS PF01740.16 EGG07976.1 - 0.091 12.1 0.0 0.24 10.8 0.0 1.7 1 1 0 1 1 1 0 STAS domain AAA_33 PF13671.1 EGG07976.1 - 0.096 12.5 0.2 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGG07976.1 - 0.1 12.7 0.1 0.6 10.3 0.1 2.0 1 1 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 EGG07976.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Herpes_gI PF01688.12 EGG07977.1 - 0.1 11.7 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I Macoilin PF09726.4 EGG07978.1 - 1.4 7.0 9.7 1.4 7.0 6.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Vfa1 PF08432.5 EGG07978.1 - 4.2 7.3 11.6 5.4 7.0 8.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2956 PF11169.3 EGG07978.1 - 5.3 7.0 9.8 1.8 8.5 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2956) FAM60A PF15396.1 EGG07978.1 - 7.4 6.2 8.9 8.9 5.9 6.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.2 EGG07978.1 - 9.5 3.7 16.0 12 3.4 11.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ctr PF04145.10 EGG07980.1 - 4.2e-26 91.7 3.2 4.9e-26 91.4 2.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF1772 PF08592.6 EGG07980.1 - 0.075 12.7 0.1 0.28 10.9 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Ctr PF04145.10 EGG07981.1 - 1.8e-29 102.6 0.0 2e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family DUF4381 PF14316.1 EGG07981.1 - 0.0077 16.3 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Joubert PF15392.1 EGG07982.1 - 0.033 13.4 1.0 0.05 12.8 0.7 1.2 1 0 0 1 1 1 0 Joubert syndrome-associated ADH_N PF08240.7 EGG07991.1 - 0.056 13.2 0.5 0.059 13.1 0.3 1.1 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain RNA_pol_3_Rpc31 PF11705.3 EGG07993.1 - 2.4 8.0 22.5 6.1 6.7 15.6 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 zinc-ribbons_6 PF07191.7 EGG07994.1 - 3.4 7.5 9.3 12 5.7 0.1 2.9 2 1 1 3 3 3 0 zinc-ribbons Dynamin_M PF01031.15 EGG07995.1 - 7.3e-67 225.2 0.0 1.2e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 EGG07995.1 - 1.3e-26 92.2 1.1 2.6e-26 91.3 0.8 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain Sugar_tr PF00083.19 EGG07997.1 - 1.2e-106 357.0 21.1 4.3e-104 348.5 14.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG07997.1 - 1.1e-28 99.9 40.8 1.4e-26 93.0 16.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EGG07997.1 - 6.4e-05 21.8 1.4 6.4e-05 21.8 1.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF791) Myosin_head PF00063.16 EGG07998.1 - 1.7e-47 161.9 0.0 2e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Chitin_synth_2 PF03142.10 EGG07999.1 - 2.8e-239 794.9 0.2 3.5e-239 794.6 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 EGG07999.1 - 8.7e-17 61.6 0.0 2.9e-13 50.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGG07999.1 - 2.5e-15 56.7 4.5 2.5e-15 56.7 3.1 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 EGG07999.1 - 3.7e-15 55.4 0.0 1.6e-09 37.4 0.0 2.5 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 EGG07999.1 - 5.6e-08 32.6 0.0 4.3e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGG07999.1 - 0.001 18.3 0.0 0.053 12.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 DEK_C PF08766.6 EGG08000.1 - 1.8e-14 53.2 0.0 2.1e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 DEK C terminal domain Homeobox_KN PF05920.6 EGG08000.1 - 0.048 13.3 0.1 0.08 12.6 0.1 1.2 1 0 0 1 1 1 0 Homeobox KN domain HipA_C PF07804.7 EGG08000.1 - 0.06 13.4 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 HipA-like C-terminal domain Cornichon PF03311.9 EGG08001.1 - 4.4e-16 59.1 0.2 4.5e-16 59.1 0.2 1.0 1 0 0 1 1 1 1 Cornichon protein DUF285 PF03382.9 EGG08001.1 - 0.046 13.2 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 Cornichon PF03311.9 EGG08002.1 - 1.3e-47 161.1 10.9 1.5e-47 160.9 7.6 1.0 1 0 0 1 1 1 1 Cornichon protein EI24 PF07264.6 EGG08002.1 - 0.12 11.8 7.5 0.19 11.1 5.2 1.3 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF285 PF03382.9 EGG08002.1 - 0.12 11.9 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 BTP PF05232.7 EGG08002.1 - 0.12 12.1 0.2 0.12 12.1 0.2 2.8 3 0 0 3 3 3 0 Bacterial Transmembrane Pair family DUF2755 PF10954.3 EGG08002.1 - 8.4 6.1 6.7 0.3 10.8 0.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2755) MIS13 PF08202.6 EGG08003.1 - 2.8e-05 23.3 0.0 4.3e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Mis12-Mtw1 protein family Calcipressin PF04847.7 EGG08003.1 - 0.017 14.7 0.1 0.017 14.7 0.0 1.8 2 0 0 2 2 2 0 Calcipressin Tmemb_cc2 PF10267.4 EGG08003.1 - 0.072 11.6 0.3 0.11 11.0 0.2 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MUG2_C PF08593.5 EGG08003.1 - 0.21 11.8 1.7 0.48 10.6 0.2 2.4 1 1 1 2 2 2 0 Meiotically up-regulated glycoproteins C-terminal UPF0160 PF03690.8 EGG08004.1 - 2.5e-05 23.8 0.2 4.4e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) SWIB PF02201.13 EGG08008.1 - 1.5e-25 88.6 0.3 2.3e-25 88.0 0.2 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EGG08008.1 - 0.054 13.2 0.1 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 DEK C terminal domain Methyltransf_16 PF10294.4 EGG08009.1 - 8.6e-19 67.6 0.1 1.2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGG08009.1 - 1.2e-06 28.0 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EGG08009.1 - 1.4e-05 25.5 0.0 2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGG08009.1 - 0.00022 20.4 0.0 0.00027 20.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGG08009.1 - 0.0009 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG08009.1 - 0.053 13.1 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Hydrolase PF00702.21 EGG08010.1 - 2.5e-22 80.3 0.0 5.8e-22 79.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGG08010.1 - 8.7e-22 78.2 0.1 1.6e-21 77.3 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGG08010.1 - 4.7e-20 71.6 0.0 9.5e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EGG08010.1 - 0.00091 19.1 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGG08010.1 - 0.016 14.7 0.0 0.054 13.0 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase VID27 PF08553.5 EGG08011.1 - 6.2e-112 375.3 0.2 7.4e-112 375.0 0.1 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein HIRA_B PF09453.5 EGG08011.1 - 3.9 7.1 6.7 0.38 10.3 0.3 2.5 3 0 0 3 3 3 0 HIRA B motif TraI_2 PF07514.6 EGG08012.1 - 0.0091 14.8 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Putative helicase LEA_3 PF03242.8 EGG08013.1 - 1.2 9.4 3.9 10 6.4 0.0 3.2 3 1 0 3 3 3 0 Late embryogenesis abundant protein FAR1 PF03101.10 EGG08015.1 - 2.7e-05 24.5 0.9 0.00013 22.4 0.4 2.3 2 0 0 2 2 2 1 FAR1 DNA-binding domain OTU PF02338.14 EGG08015.1 - 0.00039 20.9 0.0 0.0011 19.5 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease HECT_2 PF09814.4 EGG08016.1 - 5.9e-10 38.3 0.1 7.4e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Suc_Fer-like PF06999.7 EGG08017.1 - 1.9e-28 100.0 0.0 3e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fer2 PF00111.22 EGG08017.1 - 1.5e-07 31.0 0.4 3e-07 30.1 0.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Aldedh PF00171.17 EGG08018.1 - 3.1e-94 315.9 0.0 4e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Complex1_30kDa PF00329.14 EGG08019.1 - 4.2e-35 120.0 0.0 6.4e-35 119.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit UPF0175 PF03683.8 EGG08020.1 - 0.084 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) DUF1396 PF07161.8 EGG08021.1 - 0.077 12.6 0.0 0.098 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1396) Cellulase PF00150.13 EGG08022.1 - 1.1e-07 31.3 0.0 2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ETRAMP PF09716.5 EGG08022.1 - 0.0015 18.4 0.0 0.0047 16.8 0.0 1.8 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) Peptidase_M28 PF04389.12 EGG08023.1 - 7.3e-22 77.9 0.0 2.2e-21 76.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGG08023.1 - 4.8e-05 22.9 0.0 0.00015 21.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 U1snRNP70_N PF12220.3 EGG08024.1 - 0.01 16.1 0.3 0.023 15.0 0.2 1.5 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Tet_JBP PF12851.2 EGG08024.1 - 0.073 12.3 2.0 0.31 10.3 0.3 2.4 2 1 1 3 3 3 0 Oxygenase domain of the 2OGFeDO superfamily KMP11 PF03037.11 EGG08024.1 - 0.082 13.5 1.7 0.15 12.7 1.2 1.5 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 SF-assemblin PF06705.6 EGG08024.1 - 0.085 11.9 6.9 0.53 9.3 0.0 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin CortBP2 PF09727.4 EGG08024.1 - 0.12 11.9 3.6 0.069 12.6 1.2 1.5 2 0 0 2 2 2 0 Cortactin-binding protein-2 Mit_KHE1 PF10173.4 EGG08024.1 - 0.15 11.8 1.3 0.21 11.4 0.9 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Apolipoprotein PF01442.13 EGG08024.1 - 0.21 11.0 5.8 0.5 9.8 3.5 1.7 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.10 EGG08024.1 - 3.2 6.8 10.0 1.5 7.9 4.7 1.8 1 1 1 2 2 2 0 Exonuclease VII, large subunit GIY-YIG PF01541.19 EGG08025.1 - 5.9 7.3 6.0 0.99 9.8 0.8 2.3 3 0 0 3 3 3 0 GIY-YIG catalytic domain Met_gamma_lyase PF06838.6 EGG08027.1 - 0.038 12.2 0.0 0.049 11.9 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase Uds1 PF15456.1 EGG08027.1 - 0.084 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Up-regulated During Septation ECH PF00378.15 EGG08028.1 - 4.5e-59 199.5 0.0 5.5e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family GrpE PF01025.14 EGG08029.1 - 9e-45 152.1 0.0 1.2e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 GrpE DUF3408 PF11888.3 EGG08029.1 - 0.093 12.6 2.7 0.18 11.7 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3408) TB2_DP1_HVA22 PF03134.14 EGG08031.1 - 0.0004 20.0 1.4 0.0004 20.0 0.9 2.3 2 0 0 2 2 2 1 TB2/DP1, HVA22 family CHCH PF06747.8 EGG08032.1 - 0.0011 18.7 6.5 0.0011 18.7 4.5 2.2 2 0 0 2 2 2 1 CHCH domain Pet191_N PF10203.4 EGG08032.1 - 0.33 11.0 9.9 1.1 9.4 3.4 2.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 NOB1_Zn_bind PF08772.6 EGG08033.1 - 6.1e-24 83.6 0.8 1.1e-23 82.8 0.6 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-AN1 PF01428.11 EGG08034.1 - 0.11 12.4 0.5 0.23 11.3 0.4 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger PCI PF01399.22 EGG08036.1 - 5.8e-08 32.9 0.3 5.8e-08 32.9 0.2 2.6 4 0 0 4 4 4 1 PCI domain DUF663 PF04950.7 EGG08036.1 - 0.00065 18.7 1.7 0.001 18.1 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) Pkinase PF00069.20 EGG08037.1 - 2.6e-05 23.5 0.0 3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain GldH_lipo PF14109.1 EGG08037.1 - 0.0094 16.1 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 1 GldH lipoprotein Pkinase_Tyr PF07714.12 EGG08037.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Tbf5 PF06331.7 EGG08042.1 - 9.2e-20 70.1 0.0 1.3e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 NIF PF03031.13 EGG08043.1 - 2.6e-33 114.9 0.0 3.9e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Trichoplein PF13868.1 EGG08043.1 - 0.0051 15.2 2.1 0.0051 15.2 1.4 1.8 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin RNase_P_pop3 PF08228.6 EGG08044.1 - 0.015 15.0 0.0 0.12 12.2 0.0 2.5 1 1 0 1 1 1 0 RNase P subunit Pop3 DUF1128 PF06569.6 EGG08045.1 - 0.097 12.4 0.1 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) FUSC_2 PF13515.1 EGG08047.1 - 0.36 10.7 4.7 0.54 10.1 3.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein-like DUF3454 PF11936.3 EGG08048.1 - 0.079 13.1 1.7 0.13 12.5 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3454) AAA PF00004.24 EGG08049.1 - 6.4e-57 191.4 0.0 2.3e-44 150.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EGG08049.1 - 2.7e-20 72.2 1.7 6.9e-20 70.8 1.2 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EGG08049.1 - 2.2e-09 37.5 2.1 0.0035 17.3 0.1 3.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EGG08049.1 - 4e-08 33.4 1.5 0.0093 16.1 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGG08049.1 - 4.1e-08 34.0 0.0 0.0048 17.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EGG08049.1 - 7.9e-07 29.0 0.0 0.037 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EGG08049.1 - 1.9e-06 27.8 0.0 0.059 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EGG08049.1 - 5.8e-06 26.0 3.9 0.35 10.5 0.1 4.2 3 1 1 4 4 4 2 NACHT domain Zeta_toxin PF06414.7 EGG08049.1 - 1.2e-05 24.5 0.0 0.034 13.2 0.0 3.0 3 0 0 3 3 2 2 Zeta toxin AAA_5 PF07728.9 EGG08049.1 - 1.3e-05 24.9 0.1 0.18 11.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGG08049.1 - 1.5e-05 24.9 0.0 0.004 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EGG08049.1 - 1.6e-05 25.0 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Viral_helicase1 PF01443.13 EGG08049.1 - 3e-05 23.6 0.0 0.069 12.6 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 EGG08049.1 - 0.00015 20.9 0.0 0.0021 17.1 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EGG08049.1 - 0.0003 21.1 0.0 0.73 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EGG08049.1 - 0.00045 19.4 0.2 0.1 11.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EGG08049.1 - 0.00055 20.2 0.0 0.36 11.1 0.0 3.0 2 1 1 3 3 2 1 ABC transporter Arch_ATPase PF01637.13 EGG08049.1 - 0.0006 19.5 0.0 1.5 8.4 0.0 3.6 3 1 1 4 4 3 1 Archaeal ATPase AAA_25 PF13481.1 EGG08049.1 - 0.0011 18.4 6.1 0.69 9.2 0.1 4.3 2 2 0 4 4 4 1 AAA domain AAA_19 PF13245.1 EGG08049.1 - 0.0011 18.6 0.1 2.1 8.1 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain Miro PF08477.8 EGG08049.1 - 0.0048 17.3 0.2 0.11 12.9 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein cobW PF02492.14 EGG08049.1 - 0.0053 16.2 0.2 0.51 9.7 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain TIP49 PF06068.8 EGG08049.1 - 0.0053 15.5 0.0 0.052 12.2 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 EGG08049.1 - 0.0075 15.7 0.3 0.44 9.9 0.0 2.7 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_24 PF13479.1 EGG08049.1 - 0.0082 15.7 2.3 2 7.9 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EGG08049.1 - 0.0083 16.0 0.2 3.2 7.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain T2SE PF00437.15 EGG08049.1 - 0.011 14.6 0.0 0.28 10.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_3 PF07726.6 EGG08049.1 - 0.02 14.4 0.0 0.42 10.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EGG08049.1 - 0.026 13.4 0.0 2.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 EGG08049.1 - 0.029 14.0 0.0 6.7 6.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein NB-ARC PF00931.17 EGG08049.1 - 0.04 12.7 0.0 0.9 8.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activ_2 PF14532.1 EGG08049.1 - 0.042 13.8 0.0 5.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain UPF0079 PF02367.12 EGG08049.1 - 0.044 13.4 0.0 16 5.1 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EGG08049.1 - 0.058 13.0 0.1 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 EGG08049.1 - 0.069 11.8 0.3 0.78 8.3 0.0 2.4 2 1 1 3 3 3 0 Rad17 cell cycle checkpoint protein FtsK_SpoIIIE PF01580.13 EGG08049.1 - 0.089 12.2 0.0 0.84 9.0 0.0 2.4 3 0 0 3 3 2 0 FtsK/SpoIIIE family SKI PF01202.17 EGG08049.1 - 0.098 12.5 0.1 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.10 EGG08049.1 - 0.1 12.2 0.1 7.2 6.2 0.0 2.4 2 0 0 2 2 2 0 NTPase Cytidylate_kin2 PF13189.1 EGG08049.1 - 0.12 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family Sigma54_activat PF00158.21 EGG08049.1 - 0.12 11.8 0.0 21 4.5 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain Kin17_mid PF10357.4 EGG08050.1 - 0.14 11.8 1.7 0.27 10.8 1.1 1.4 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Cache_1 PF02743.13 EGG08053.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Cache domain FimP PF09766.4 EGG08057.1 - 6.3e-31 107.7 9.7 7.5e-31 107.4 6.7 1.1 1 0 0 1 1 1 1 Fms-interacting protein ATG16 PF08614.6 EGG08057.1 - 0.013 15.2 8.5 0.025 14.4 1.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1465 PF07323.7 EGG08057.1 - 0.023 14.2 5.0 0.52 9.8 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1465) FoP_duplication PF13865.1 EGG08057.1 - 0.065 13.6 2.0 0.11 12.8 1.4 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Seryl_tRNA_N PF02403.17 EGG08057.1 - 0.11 12.5 8.5 0.35 10.9 2.9 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mod_r PF07200.8 EGG08057.1 - 0.56 10.1 12.1 1.6 8.6 3.7 2.5 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2630 PF10944.3 EGG08057.1 - 0.87 9.7 6.3 0.5 10.5 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) APG6 PF04111.7 EGG08057.1 - 9.7 5.1 11.7 10 5.0 0.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 RRM_1 PF00076.17 EGG08059.1 - 4.6e-13 48.5 0.0 5.3e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG08059.1 - 1.2e-07 31.5 0.0 1.3e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGG08060.1 - 1.8e-16 59.5 0.0 2.1e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG08060.1 - 1e-11 44.6 0.0 1.2e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG08060.1 - 3.2e-11 42.9 0.0 3.7e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGG08060.1 - 3.2e-06 26.8 0.0 4.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EGG08060.1 - 6.1e-06 26.0 0.0 6.9e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 RNA binding motif Metallophos PF00149.23 EGG08061.1 - 4.7e-05 22.8 8.2 0.00047 19.6 5.7 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGG08061.1 - 0.00015 21.6 0.0 0.00051 19.9 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Adaptin_N PF01602.15 EGG08062.1 - 2.6e-126 422.0 14.7 3.5e-126 421.5 10.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EGG08062.1 - 1e-39 134.9 0.1 4.4e-39 132.9 0.0 2.1 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EGG08062.1 - 5.8e-22 78.1 0.0 2.1e-21 76.3 0.0 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain Ank_2 PF12796.2 EGG08062.1 - 0.019 15.3 0.4 8 6.8 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) DUF3642 PF12182.3 EGG08062.1 - 0.072 13.5 0.0 3.8 8.0 0.0 2.7 2 0 0 2 2 2 0 Bacterial lipoprotein PGG PF13962.1 EGG08064.1 - 0.028 14.0 0.8 0.046 13.3 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function EXS PF03124.9 EGG08064.1 - 0.033 13.1 1.8 0.037 13.0 1.3 1.2 1 0 0 1 1 1 0 EXS family DUF3481 PF11980.3 EGG08064.1 - 1 9.2 4.3 2.1 8.2 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3481) Ribosomal_L7Ae PF01248.21 EGG08065.1 - 1.7e-27 94.7 2.2 2.2e-27 94.4 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NUDIX PF00293.23 EGG08067.1 - 4.4e-13 49.0 0.0 7.2e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Cobalamin_bind PF01122.14 EGG08068.1 - 0.013 14.0 2.2 0.015 13.9 1.5 1.1 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein Fib_alpha PF08702.5 EGG08068.1 - 2.4 8.2 9.1 2.8 8.0 6.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MFS_1 PF07690.11 EGG08069.1 - 2.7e-19 69.0 21.8 7.5e-15 54.4 6.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EGG08069.1 - 9e-14 51.3 10.1 1.9e-13 50.2 3.5 3.1 2 1 0 2 2 2 1 Nodulin-like DUF4328 PF14219.1 EGG08069.1 - 0.17 11.1 2.1 0.28 10.4 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) PIRT PF15099.1 EGG08069.1 - 1.7 7.8 5.1 20 4.3 0.1 3.2 2 1 1 3 3 3 0 Phosphoinositide-interacting protein family Glyco_hydro_2_N PF02837.13 EGG08070.1 - 3.2e-24 85.3 0.2 6.7e-24 84.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EGG08070.1 - 7.6e-11 41.4 0.0 1.1e-09 37.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EGG08070.1 - 7.5e-09 36.0 0.0 1.8e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 G-gamma PF00631.17 EGG08071.1 - 1.2 8.8 4.4 0.83 9.4 1.1 2.1 2 1 0 2 2 2 0 GGL domain zf-CCHC PF00098.18 EGG08074.1 - 0.036 14.0 2.9 0.036 14.0 2.0 3.3 3 0 0 3 3 3 0 Zinc knuckle PhoU PF01895.14 EGG08074.1 - 0.25 11.8 1.6 0.45 11.0 1.1 1.4 1 0 0 1 1 1 0 PhoU domain DUF2890 PF11081.3 EGG08078.1 - 0.22 11.5 7.3 0.33 10.9 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) U1snRNP70_N PF12220.3 EGG08078.1 - 1.9 8.8 9.8 0.077 13.3 2.5 1.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal IBR PF01485.16 EGG08086.1 - 0.01 15.6 4.0 0.12 12.3 2.1 2.0 1 1 1 2 2 2 0 IBR domain zf-Di19 PF05605.7 EGG08086.1 - 0.047 13.8 0.4 0.07 13.2 0.3 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EGG08086.1 - 0.061 13.6 0.4 0.061 13.6 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-TRAF PF02176.13 EGG08086.1 - 0.081 13.3 1.1 4.3 7.7 0.0 2.1 1 1 0 2 2 2 0 TRAF-type zinc finger PRP21_like_P PF12230.3 EGG08086.1 - 0.11 11.9 0.6 0.14 11.5 0.4 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein DUF3583 PF12126.3 EGG08086.1 - 6.3 5.7 6.0 7.1 5.5 3.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3583) Whi5 PF08528.6 EGG08087.1 - 3.5e-05 23.3 0.2 9.5e-05 21.9 0.1 1.8 1 0 0 1 1 1 1 Whi5 like Mito_carr PF00153.22 EGG08089.1 - 3.4e-70 231.8 7.0 2.9e-24 84.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.19 EGG08090.1 - 2.4e-49 168.1 20.1 2.9e-49 167.8 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG08090.1 - 1.8e-20 72.9 27.8 1.8e-20 72.9 19.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.10 EGG08090.1 - 0.0072 15.0 0.1 0.0072 15.0 0.1 1.8 2 0 0 2 2 2 1 MMPL family ADK PF00406.17 EGG08091.1 - 1.9e-46 157.7 0.0 2.5e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EGG08091.1 - 2.5e-11 43.9 0.0 3.4e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG08091.1 - 1.1e-06 29.4 0.0 2.2e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGG08091.1 - 3.7e-05 23.6 0.0 0.00021 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EGG08091.1 - 0.0002 20.7 0.2 0.36 10.1 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 EGG08091.1 - 0.054 12.5 0.0 0.075 12.1 0.0 1.4 1 1 0 1 1 1 0 Zeta toxin N2227 PF07942.7 EGG08094.1 - 1.8e-78 263.2 0.0 2e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EGG08094.1 - 4.8e-08 32.8 0.0 8.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG08094.1 - 3.6e-06 27.3 0.0 5.1e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG08094.1 - 0.00031 21.1 0.0 0.013 15.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG08094.1 - 0.0087 15.6 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG08094.1 - 0.019 15.5 0.0 0.11 13.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EGG08094.1 - 0.024 14.6 0.0 0.12 12.3 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_8 PF05148.10 EGG08094.1 - 0.14 11.7 0.0 0.41 10.2 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase INTS5_C PF14838.1 EGG08095.1 - 0.028 12.7 0.1 0.038 12.2 0.1 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus CTP_transf_1 PF01148.15 EGG08096.1 - 0.032 13.8 0.2 0.037 13.6 0.2 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family IFN-gamma PF00714.12 EGG08097.1 - 0.014 15.1 1.6 0.014 15.1 1.1 1.9 1 1 0 2 2 2 0 Interferon gamma WD40 PF00400.27 EGG08098.1 - 2.6e-27 93.6 15.5 6.6e-06 25.8 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF2201_N PF13203.1 EGG08098.1 - 0.4 9.7 2.8 0.29 10.2 0.4 1.8 1 1 1 2 2 2 0 Putative metallopeptidase domain NAD_kinase PF01513.16 EGG08099.1 - 9e-70 234.6 0.0 1.3e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase zf-H2C2_2 PF13465.1 EGG08100.1 - 0.059 13.6 3.1 0.079 13.2 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain IBR PF01485.16 EGG08100.1 - 0.21 11.5 1.7 0.58 10.0 1.2 1.6 1 1 0 1 1 1 0 IBR domain zf-C2H2_4 PF13894.1 EGG08100.1 - 0.23 11.8 1.3 1.7 9.1 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3583 PF12126.3 EGG08100.1 - 0.62 9.0 2.8 0.88 8.5 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Mob1_phocein PF03637.12 EGG08101.1 - 6.4e-58 195.2 0.0 7.6e-58 195.0 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family WYL PF13280.1 EGG08101.1 - 0.18 11.6 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 WYL domain Macoilin PF09726.4 EGG08102.1 - 5.2 5.2 7.8 5.8 5.0 5.4 1.0 1 0 0 1 1 1 0 Transmembrane protein TatD_DNase PF01026.16 EGG08103.1 - 1.8e-32 112.5 0.0 2.6e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase UBA_3 PF09288.5 EGG08103.1 - 0.067 12.8 0.3 1.1 8.8 0.0 3.0 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF4028 PF13220.1 EGG08104.1 - 0.043 13.4 0.1 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) Sec62 PF03839.11 EGG08105.1 - 2.4 7.5 4.8 3.3 7.0 3.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 SAICAR_synt PF01259.13 EGG08106.1 - 1.7e-77 259.8 0.2 2.1e-77 259.6 0.1 1.0 1 0 0 1 1 1 1 SAICAR synthetase CDC45 PF02724.9 EGG08109.1 - 0.081 10.9 3.4 0.088 10.8 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 EGG08109.1 - 0.67 9.3 5.2 0.73 9.2 3.5 1.2 1 1 0 1 1 1 0 Spore coat protein CotO TT_ORF2 PF02957.10 EGG08109.1 - 1.3 9.7 8.7 2.2 8.9 5.8 1.6 1 1 0 1 1 1 0 TT viral ORF2 G-patch PF01585.18 EGG08110.1 - 0.0016 18.2 0.0 0.0082 15.9 0.0 2.1 2 0 0 2 2 2 1 G-patch domain CENP-B_dimeris PF09026.5 EGG08111.1 - 4.8 7.4 8.1 10 6.3 5.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tet_JBP PF12851.2 EGG08112.1 - 2.3e-05 23.7 0.1 5.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Cyclase_polyket PF04673.7 EGG08112.1 - 0.042 13.8 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Polyketide synthesis cyclase hDGE_amylase PF14701.1 EGG08113.1 - 9.5e-11 41.2 0.1 2.2e-10 40.0 0.1 1.5 1 1 1 2 2 2 2 glucanotransferase domain of human glycogen debranching enzyme Arf PF00025.16 EGG08115.1 - 1.4e-72 242.6 0.0 1.6e-72 242.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGG08115.1 - 3.2e-11 42.8 0.0 3.8e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EGG08115.1 - 3.6e-11 42.4 1.6 3.2e-07 29.3 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGG08115.1 - 8e-11 41.5 0.0 9.6e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGG08115.1 - 2.5e-10 39.8 0.0 3.1e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EGG08115.1 - 3e-06 27.7 0.0 4.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGG08115.1 - 0.00036 20.4 0.0 0.00054 19.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase WHIM2 PF15613.1 EGG08115.1 - 0.094 12.6 0.1 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 2 eIF-4B PF06273.6 EGG08117.1 - 0.91 8.1 4.8 0.91 8.1 3.3 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Corona_NS8 PF12093.3 EGG08118.1 - 0.0039 17.5 0.0 0.45 10.8 0.0 2.4 2 0 0 2 2 2 2 Coronavirus NS8 protein Corona_NS8 PF12093.3 EGG08120.1 - 0.054 13.8 1.0 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 Coronavirus NS8 protein SAC3_GANP PF03399.11 EGG08121.1 - 3.3e-61 206.4 2.0 4.9e-61 205.8 1.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGG08121.1 - 6.6e-07 29.2 0.8 3.2e-06 26.9 0.3 2.2 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 UPF0160 PF03690.8 EGG08123.1 - 1.7e-28 100.0 0.2 2.1e-28 99.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Alg14 PF08660.6 EGG08132.1 - 6.6e-51 172.6 0.0 8.8e-51 172.2 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like CTD_bind PF04818.8 EGG08138.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II-binding domain. OsmC PF02566.14 EGG08139.1 - 0.32 11.2 2.0 0.54 10.4 0.1 2.3 3 0 0 3 3 3 0 OsmC-like protein DUF1129 PF06570.6 EGG08140.1 - 7.1 5.8 17.1 2.2 7.5 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Sigma70_ner PF04546.8 EGG08141.1 - 0.093 12.3 4.1 0.098 12.2 2.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 EGG08141.1 - 0.29 11.4 4.2 0.42 10.8 2.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Paf1 PF03985.8 EGG08141.1 - 1.1 7.9 5.1 1.2 7.8 3.6 1.1 1 0 0 1 1 1 0 Paf1 Nucleoplasmin PF03066.10 EGG08141.1 - 1.3 8.5 6.4 1.4 8.3 4.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 EGG08141.1 - 1.8 6.9 8.9 1.9 6.8 6.2 1.0 1 0 0 1 1 1 0 Daxx Family SnoaL_2 PF12680.2 EGG08142.1 - 0.0013 19.1 0.1 0.0033 17.7 0.0 1.6 2 0 0 2 2 2 1 SnoaL-like domain SnoaL_2 PF12680.2 EGG08143.1 - 0.0023 18.3 0.0 0.0033 17.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain PHF5 PF03660.9 EGG08144.1 - 3.5e-50 168.5 9.7 3.8e-50 168.4 6.7 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EGG08144.1 - 0.31 10.8 15.7 21 5.0 10.9 2.8 1 1 0 1 1 1 0 Double zinc ribbon PHD PF00628.24 EGG08144.1 - 0.99 9.1 14.0 0.035 13.7 3.5 2.8 1 1 2 3 3 3 0 PHD-finger Prok-RING_1 PF14446.1 EGG08144.1 - 1.1 9.0 15.4 2.4 7.9 0.4 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 AA_permease PF00324.16 EGG08145.1 - 2.5e-50 171.2 28.0 1e-49 169.1 19.4 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGG08145.1 - 4.3e-18 65.0 29.1 6.1e-18 64.5 20.2 1.1 1 0 0 1 1 1 1 Amino acid permease SH PF01445.12 EGG08145.1 - 0.0015 18.1 0.3 0.0057 16.2 0.2 2.0 1 0 0 1 1 1 1 Viral small hydrophobic protein Band_3_cyto PF07565.8 EGG08146.1 - 0.06 12.8 2.8 0.079 12.4 1.5 1.6 1 1 0 1 1 1 0 Band 3 cytoplasmic domain Kelch_4 PF13418.1 EGG08148.1 - 0.019 14.7 0.9 0.048 13.4 0.6 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain Acetyltransf_1 PF00583.19 EGG08149.1 - 4.4e-09 36.2 0.1 1.9e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGG08149.1 - 0.0018 18.3 0.1 0.004 17.2 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGG08149.1 - 0.0024 17.9 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L7Ae PF01248.21 EGG08150.1 - 5.8e-22 77.0 0.0 6.7e-22 76.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PMM PF03332.8 EGG08151.1 - 3.5e-110 366.8 3.2 4e-110 366.6 2.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EGG08151.1 - 8.9e-07 28.7 0.0 4.4e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EGG08151.1 - 0.00024 20.4 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.8 EGG08151.1 - 0.00094 18.3 0.1 0.0012 18.0 0.1 1.1 1 0 0 1 1 1 1 TMPIT-like protein Humanin PF15040.1 EGG08151.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Humanin family Chordopox_A13L PF05961.6 EGG08151.1 - 0.15 12.0 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Actin PF00022.14 EGG08152.1 - 4.9e-26 91.0 0.0 7.2e-25 87.2 0.0 2.4 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGG08152.1 - 0.00088 17.9 0.0 0.029 12.9 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein E1-E2_ATPase PF00122.15 EGG08153.1 - 8.4e-06 24.9 0.1 9.2e-06 24.8 0.1 1.0 1 0 0 1 1 1 1 E1-E2 ATPase DUF4218 PF13960.1 EGG08154.1 - 3.8e-05 23.1 0.7 9.4e-05 21.8 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) CCDC-167 PF15188.1 EGG08156.1 - 0.0077 16.1 0.7 0.014 15.3 0.5 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 TPR_11 PF13414.1 EGG08156.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_6 PF13174.1 EGG08156.1 - 0.13 12.7 1.0 0.24 11.9 0.2 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Chromo PF00385.19 EGG08158.1 - 4.4e-12 45.4 1.2 4.4e-12 45.4 0.8 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EGG08158.1 - 3e-06 26.9 1.2 5.2e-06 26.2 0.0 2.0 3 0 0 3 3 3 1 Chromo shadow domain NinF PF05810.7 EGG08159.1 - 5.8 6.8 8.6 6.5 6.6 0.4 2.4 2 0 0 2 2 2 0 NinF protein Alpha_kinase PF02816.13 EGG08160.1 - 3.8e-22 78.8 0.2 5.7e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family VLPT PF07122.6 EGG08163.1 - 0.086 12.5 0.8 0.15 11.7 0.5 1.4 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) SNF2_N PF00176.18 EGG08164.1 - 1.3e-44 152.2 0.5 1.4e-44 152.1 0.4 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGG08164.1 - 5.1e-08 32.5 0.0 6.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGG08164.1 - 0.0037 17.1 0.0 0.0062 16.3 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGG08165.1 - 2.2e-13 49.8 0.0 4.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF720 PF05302.6 EGG08168.1 - 0.74 9.5 8.3 4.3 7.1 5.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF720) MIS13 PF08202.6 EGG08169.1 - 0.0065 15.5 0.4 0.0095 15.0 0.3 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family FlxA PF14282.1 EGG08169.1 - 0.032 14.1 1.9 0.056 13.3 1.3 1.4 1 0 0 1 1 1 0 FlxA-like protein DUF904 PF06005.7 EGG08169.1 - 0.26 11.6 3.1 0.77 10.0 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF2457 PF10446.4 EGG08171.1 - 2 7.0 4.5 2.4 6.8 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF605 PF04652.11 EGG08171.1 - 5.3 6.3 14.1 5.9 6.1 9.8 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 EGG08173.1 - 4.6 5.3 25.8 5.3 5.1 17.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DS PF01916.12 EGG08179.1 - 1.8e-16 60.1 0.0 2.1e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase E1_DerP2_DerF2 PF02221.10 EGG08181.1 - 5.1e-08 33.2 0.2 6.6e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 ML domain Tropomyosin_1 PF12718.2 EGG08182.1 - 3.5e-42 143.6 34.0 4.3e-42 143.3 23.6 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EGG08182.1 - 1.5e-10 40.6 33.8 5.4e-06 25.6 4.9 3.0 1 1 2 3 3 3 3 Tropomyosin CENP-F_leu_zip PF10473.4 EGG08182.1 - 0.0037 17.1 33.3 0.13 12.1 4.9 3.1 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EGG08182.1 - 0.0094 15.1 4.1 0.17 11.0 0.2 2.1 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 EGG08182.1 - 0.029 12.1 34.9 0.035 11.8 24.2 1.0 1 0 0 1 1 1 0 Myosin tail Sugarporin_N PF11471.3 EGG08182.1 - 0.046 13.3 0.6 0.046 13.3 0.4 3.2 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension HrpB7 PF09486.5 EGG08182.1 - 0.11 12.4 21.8 0.44 10.4 2.5 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Clr5 PF14420.1 EGG08182.1 - 0.15 12.0 2.0 0.34 10.8 1.4 1.6 1 0 0 1 1 1 0 Clr5 domain WEMBL PF05701.6 EGG08182.1 - 0.15 10.4 33.0 0.21 10.0 22.8 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Laminin_II PF06009.7 EGG08182.1 - 0.3 10.8 18.9 1.7 8.4 4.7 2.5 1 1 1 2 2 2 0 Laminin Domain II Lectin_N PF03954.9 EGG08182.1 - 0.31 10.4 8.3 0.12 11.8 3.1 2.2 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain CDC37_N PF03234.9 EGG08182.1 - 0.32 11.2 20.7 0.4 10.9 14.3 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4200 PF13863.1 EGG08182.1 - 0.55 10.1 30.2 1.4 8.8 10.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.3 EGG08182.1 - 0.64 9.2 21.9 2.5 7.2 7.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Mod_r PF07200.8 EGG08182.1 - 0.76 9.6 25.0 0.85 9.5 2.2 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Striatin PF08232.7 EGG08182.1 - 0.78 10.0 22.4 1.3 9.3 7.3 2.1 1 1 1 2 2 2 0 Striatin family GAS PF13851.1 EGG08182.1 - 0.86 8.7 31.2 1.5 7.9 21.6 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 EGG08182.1 - 0.87 9.3 26.3 0.52 10.0 10.2 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Pox_A_type_inc PF04508.7 EGG08182.1 - 0.88 9.5 6.0 2.1 8.3 0.0 3.6 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat ERM PF00769.14 EGG08182.1 - 0.93 8.9 35.8 0.13 11.7 8.6 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family APG6 PF04111.7 EGG08182.1 - 1 8.3 33.4 2.1 7.3 9.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Uds1 PF15456.1 EGG08182.1 - 1.3 9.0 27.3 0.84 9.6 5.3 3.1 1 1 2 3 3 3 0 Up-regulated During Septation DUF3573 PF12097.3 EGG08182.1 - 1.3 7.5 5.1 1.6 7.2 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) V_ATPase_I PF01496.14 EGG08182.1 - 1.4 6.6 16.3 1.8 6.3 11.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 EGG08182.1 - 1.5 8.6 14.9 0.39 10.5 2.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EGG08182.1 - 1.6 9.0 10.7 0.93 9.7 0.7 3.0 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 EGG08182.1 - 1.6 7.5 25.7 0.25 10.2 12.4 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EGG08182.1 - 1.9 8.0 25.9 5.2 6.6 17.9 1.8 1 1 0 1 1 1 0 IncA protein HisKA_3 PF07730.8 EGG08182.1 - 2.5 8.5 10.7 2.4 8.5 2.2 3.4 2 1 1 3 3 3 0 Histidine kinase TBPIP PF07106.8 EGG08182.1 - 2.8 7.4 26.1 3.4 7.1 12.3 2.4 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ADIP PF11559.3 EGG08182.1 - 3.1 7.7 31.1 4.4 7.1 1.0 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Occludin_ELL PF07303.8 EGG08182.1 - 3.5 8.4 16.5 4.2 8.1 0.3 3.6 1 1 2 3 3 3 0 Occludin homology domain COG2 PF06148.6 EGG08182.1 - 3.6 7.4 20.7 2.9 7.7 1.2 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2422 PF10337.4 EGG08182.1 - 3.9 6.1 9.5 4.2 6.0 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF3287 PF11690.3 EGG08182.1 - 4.1 7.5 13.7 2.7 8.1 3.1 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) End3 PF12761.2 EGG08182.1 - 6.6 6.3 20.4 2.2 7.8 11.8 1.8 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 EMP24_GP25L PF01105.19 EGG08182.1 - 7.3 6.2 17.6 3.4 7.3 5.5 2.4 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Fib_alpha PF08702.5 EGG08182.1 - 7.4 6.6 16.2 5 7.2 4.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tup_N PF08581.5 EGG08182.1 - 7.6 6.8 17.7 0.15 12.2 3.0 3.0 1 1 2 3 3 3 0 Tup N-terminal SlyX PF04102.7 EGG08182.1 - 7.7 6.9 18.0 0.58 10.5 1.2 3.5 1 1 3 4 4 4 0 SlyX BRE1 PF08647.6 EGG08182.1 - 9 6.3 28.8 15 5.6 4.9 2.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase RNase_PH PF01138.16 EGG08183.1 - 7e-20 71.6 0.1 1.1e-19 70.9 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGG08183.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 RRM_1 PF00076.17 EGG08186.1 - 8.1e-16 57.4 0.0 1.1e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG08186.1 - 4.1e-12 45.9 0.0 5.4e-12 45.5 0.0 1.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG08186.1 - 1.6e-06 27.8 0.0 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGG08186.1 - 0.0038 17.0 0.0 0.0055 16.5 0.0 1.3 1 1 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EGG08186.1 - 0.014 15.1 0.1 0.039 13.7 0.1 1.6 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GAS2 PF02187.12 EGG08189.1 - 0.0081 15.9 0.2 0.023 14.4 0.1 1.7 1 1 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain PBP PF01161.15 EGG08191.1 - 4e-11 42.9 0.0 4e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein FlgD_ig PF13860.1 EGG08191.1 - 0.018 14.7 0.5 0.65 9.7 0.0 2.5 2 0 0 2 2 2 0 FlgD Ig-like domain SSP160 PF06933.6 EGG08191.1 - 0.048 11.6 13.2 0.086 10.8 9.2 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 gpUL132 PF11359.3 EGG08191.1 - 2.3 7.4 8.2 4.7 6.4 5.7 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 Alpha_GJ PF03229.8 EGG08191.1 - 5.3 7.4 12.4 0.13 12.5 3.4 2.1 3 0 0 3 3 3 0 Alphavirus glycoprotein J DHO_dh PF01180.16 EGG08192.1 - 2e-93 312.6 0.0 2.7e-93 312.1 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EGG08192.1 - 7e-05 21.8 0.1 0.0017 17.3 0.1 2.5 2 1 0 2 2 2 1 FMN-dependent dehydrogenase ExbD PF02472.11 EGG08192.1 - 0.11 12.5 1.1 0.22 11.5 0.0 2.1 2 1 0 2 2 2 0 Biopolymer transport protein ExbD/TolR Amidase PF01425.16 EGG08195.1 - 3.6e-108 362.2 0.0 4e-108 362.0 0.0 1.0 1 0 0 1 1 1 1 Amidase zf-3CxxC PF13695.1 EGG08198.1 - 5.4 7.3 11.6 0.84 9.9 0.9 3.4 3 0 0 3 3 3 0 Zinc-binding domain Svf1 PF08622.5 EGG08201.1 - 9.2e-75 251.6 0.0 1.5e-74 250.8 0.0 1.3 1 0 0 1 1 1 1 Svf1-like DUF4587 PF15248.1 EGG08203.1 - 0.31 11.6 3.6 1.1 9.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) DUF1287 PF06940.6 EGG08205.1 - 0.064 12.6 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) MTHFR PF02219.12 EGG08206.1 - 5.9e-111 370.1 0.0 8.6e-111 369.6 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF4661 PF15576.1 EGG08210.1 - 0.032 13.8 1.5 5 6.6 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4661) CK_II_beta PF01214.13 EGG08211.1 - 2.5e-75 252.0 0.0 2.9e-75 251.8 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Arc_PepC PF06819.6 EGG08211.1 - 0.16 11.9 0.2 0.6 10.0 0.0 1.9 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain Glutaredoxin PF00462.19 EGG08213.1 - 6.2e-17 61.3 0.0 8.7e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thiol-ester_cl PF10569.4 EGG08214.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha-macro-globulin thiol-ester bond-forming region Ribosomal_S4e PF00900.15 EGG08215.1 - 1.8e-32 110.8 0.2 1.8e-32 110.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 EGG08215.1 - 7.4e-19 67.3 2.1 1.3e-18 66.5 1.5 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EGG08215.1 - 1.3e-06 27.7 1.6 1.9e-06 27.1 0.0 2.1 3 0 0 3 3 3 1 S4 domain KOW PF00467.24 EGG08215.1 - 0.00083 18.9 1.4 0.00083 18.9 1.0 2.3 3 0 0 3 3 3 1 KOW motif ECH PF00378.15 EGG08216.1 - 4.9e-27 94.6 0.0 6.4e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EGG08216.1 - 5.6e-27 94.2 0.0 9.8e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region DUF2754 PF10953.3 EGG08216.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Fungal_trans PF04082.13 EGG08218.1 - 2.6e-34 118.2 1.7 5.8e-34 117.1 1.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGG08218.1 - 2.2e-08 33.8 7.6 4.2e-08 32.9 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Neur_chan_memb PF02932.11 EGG08218.1 - 2.5 7.9 5.2 1.1 9.0 1.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Receptor_2B4 PF11465.3 EGG08220.1 - 0.0058 16.5 0.3 0.011 15.6 0.2 1.5 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 DUF3105 PF11303.3 EGG08220.1 - 0.029 14.1 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) ELMO_CED12 PF04727.8 EGG08221.1 - 1.6e-22 79.8 0.3 3.1e-22 78.9 0.2 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3675 PF12428.3 EGG08223.1 - 0.064 13.5 0.1 0.098 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) CAP PF00188.21 EGG08224.1 - 1.1e-16 61.5 0.4 1.1e-16 61.5 0.3 2.2 2 1 0 2 2 2 1 Cysteine-rich secretory protein family KAR9 PF08580.5 EGG08224.1 - 7.9 4.6 7.2 9.3 4.3 5.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 ABC_membrane PF00664.18 EGG08225.1 - 4.2e-77 259.2 33.2 1.8e-39 135.8 9.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGG08225.1 - 1.1e-47 161.7 4.0 5.5e-26 91.4 0.1 3.2 4 0 0 4 4 3 2 ABC transporter SMC_N PF02463.14 EGG08225.1 - 2.9e-11 43.0 0.0 5e-06 25.9 0.0 4.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EGG08225.1 - 3.3e-06 26.6 0.1 0.057 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EGG08225.1 - 7.7e-05 22.6 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase ArgK PF03308.11 EGG08225.1 - 0.00014 20.7 0.7 0.15 10.8 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_29 PF13555.1 EGG08225.1 - 0.0004 19.8 3.7 0.47 10.0 0.2 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGG08225.1 - 0.0006 19.8 0.4 0.28 11.1 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EGG08225.1 - 0.00097 18.3 2.3 0.048 12.8 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EGG08225.1 - 0.0027 18.1 4.4 0.26 11.7 0.0 3.3 3 0 0 3 3 3 1 Miro-like protein AAA_21 PF13304.1 EGG08225.1 - 0.0039 17.2 0.8 16 5.3 0.0 3.6 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 EGG08225.1 - 0.0053 17.5 0.1 2.5 8.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EGG08225.1 - 0.0062 16.0 0.1 2.4 7.5 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EGG08225.1 - 0.011 16.0 0.6 8.2 6.6 0.4 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EGG08225.1 - 0.012 14.5 1.5 0.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.1 EGG08225.1 - 0.022 14.8 0.2 11 6.2 0.0 3.6 5 0 0 5 5 2 0 AAA domain SbcCD_C PF13558.1 EGG08225.1 - 0.029 14.2 0.2 2.6 8.0 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EGG08225.1 - 0.032 14.0 6.0 1.3 8.8 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 EGG08225.1 - 0.048 13.3 2.3 1.1 9.0 0.2 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EGG08225.1 - 0.062 12.3 1.9 0.71 8.9 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 EGG08225.1 - 0.063 13.1 0.1 9.3 6.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.4 EGG08225.1 - 0.074 11.6 1.9 1.9 7.0 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 EGG08225.1 - 0.08 13.2 0.3 4.5 7.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EGG08225.1 - 0.09 11.7 0.5 0.72 8.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.18 EGG08225.1 - 0.14 12.0 3.6 0.14 11.9 0.6 2.3 2 0 0 2 2 2 0 Dynamin family AAA_10 PF12846.2 EGG08225.1 - 0.16 11.4 4.6 4.5 6.6 0.4 2.9 3 0 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 EGG08225.1 - 0.23 11.6 0.3 39 4.4 0.0 3.3 3 0 0 3 3 3 0 RNA helicase Ribosomal_S10 PF00338.17 EGG08228.1 - 0.12 12.2 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e LAB_N PF07578.6 EGG08230.1 - 0.041 13.8 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain CBM_X2 PF03442.9 EGG08239.1 - 0.0093 15.7 0.2 0.072 12.9 0.0 2.2 2 0 0 2 2 2 1 Carbohydrate binding domain X2 COX5B PF01215.14 EGG08240.1 - 4.9e-31 107.1 0.0 6.8e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb tRNA_Me_trans PF03054.11 EGG08241.1 - 2.1e-94 316.0 0.0 2.4e-94 315.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 EGG08241.1 - 0.00078 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.15 EGG08241.1 - 0.0016 17.9 0.3 0.0034 16.8 0.2 1.7 1 1 0 1 1 1 1 PP-loop family NAD_synthase PF02540.12 EGG08241.1 - 0.075 11.9 0.5 0.14 11.0 0.1 1.8 2 1 0 2 2 2 0 NAD synthase ThiI PF02568.9 EGG08241.1 - 0.092 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) DnaJ-X PF14308.1 EGG08242.1 - 1.2e-47 161.7 0.0 2e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 EGG08242.1 - 3.4e-21 74.7 0.2 2.5e-19 68.7 0.2 2.6 2 0 0 2 2 2 1 DnaJ domain Mito_fiss_reg PF05308.6 EGG08242.1 - 0.06 12.7 6.6 0.097 12.0 4.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator AAA_2 PF07724.9 EGG08243.1 - 3.7e-37 127.8 0.0 5.1e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGG08243.1 - 4.7e-05 23.5 0.0 7.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGG08243.1 - 0.00013 21.6 0.0 0.0005 19.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.4 EGG08243.1 - 0.0027 17.5 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.21 EGG08243.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Phe_ZIP PF08916.6 EGG08243.1 - 0.068 13.5 0.0 12 6.3 0.0 2.9 3 0 0 3 3 3 0 Phenylalanine zipper Na_Ca_ex PF01699.19 EGG08244.1 - 2.6e-40 137.2 32.7 1e-20 73.7 7.7 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein RNA_pol_Rpo13 PF12136.3 EGG08244.1 - 0.03 14.0 3.2 0.058 13.0 2.2 1.4 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain HTHP PF11534.3 EGG08245.1 - 0.14 12.2 0.4 0.36 10.9 0.3 1.6 1 0 0 1 1 1 0 Hexameric tyrosine-coordinated heme protein (HTHP) Voldacs PF03517.8 EGG08249.1 - 0.24 11.2 8.4 0.51 10.1 2.0 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling CENP-H PF05837.7 EGG08249.1 - 3.4 7.8 6.7 2.9 8.1 0.1 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF951 PF06107.6 EGG08256.1 - 0.052 13.0 0.1 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) Peptidase_C54 PF03416.14 EGG08259.1 - 2.6e-11 43.2 0.0 3.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 TrmE_N PF10396.4 EGG08260.1 - 1.1e-20 73.7 0.0 1.6e-19 69.9 0.0 2.4 3 0 0 3 3 3 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 EGG08260.1 - 1.1e-14 54.3 0.0 3.4e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGG08260.1 - 1.6e-05 24.2 0.0 3.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGG08260.1 - 7.2e-05 22.6 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EGG08260.1 - 0.013 16.0 0.0 0.07 13.6 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EGG08260.1 - 0.035 13.2 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Cas_GSU0054 PF09609.5 EGG08260.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) AAA_17 PF13207.1 EGG08260.1 - 0.12 13.1 0.0 0.6 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2420 PF10336.4 EGG08262.1 - 1e-12 47.6 0.0 2.8e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) SLAC1 PF03595.12 EGG08265.1 - 6e-47 159.9 44.5 6.8e-47 159.7 30.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel OTU PF02338.14 EGG08266.1 - 1.1e-05 26.0 0.0 2.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease FAR1 PF03101.10 EGG08266.1 - 0.00017 22.0 0.0 0.00033 21.1 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Peptidase_C65 PF10275.4 EGG08266.1 - 0.00097 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain Trehalose_PPase PF02358.11 EGG08269.1 - 4e-40 137.2 0.2 3e-25 88.5 0.0 2.1 1 1 1 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.7 EGG08269.1 - 4.4e-07 29.7 0.0 6.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_25 PF13481.1 EGG08269.1 - 0.069 12.5 0.0 0.98 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2183 PF09949.4 EGG08269.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Cutinase PF01083.17 EGG08270.1 - 1.3e-29 103.2 0.2 1.6e-29 102.9 0.1 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EGG08270.1 - 0.00058 19.3 0.1 0.001 18.5 0.0 1.4 2 0 0 2 2 2 1 PE-PPE domain Abhydrolase_6 PF12697.2 EGG08270.1 - 0.0013 18.6 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 EGG08270.1 - 0.0022 17.5 0.0 0.038 13.4 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase VirJ PF06057.6 EGG08270.1 - 0.033 13.9 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Rad51 PF08423.6 EGG08271.1 - 2.9e-10 39.5 0.0 3.3e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 HHH_5 PF14520.1 EGG08271.1 - 5.7e-07 29.6 0.2 1.4e-06 28.3 0.1 1.6 1 1 0 1 1 1 1 Helix-hairpin-helix domain CBF PF03914.12 EGG08274.1 - 4.3e-21 75.0 0.0 1.5e-20 73.2 0.0 2.0 1 0 0 1 1 1 1 CBF/Mak21 family NOC3p PF07540.6 EGG08274.1 - 7.1e-20 71.0 0.0 2.6e-19 69.2 0.0 2.0 1 0 0 1 1 1 1 Nucleolar complex-associated protein TAN PF11640.3 EGG08275.1 - 4.5e-13 49.2 3.5 6.1e-13 48.7 0.6 2.6 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair HEAT PF02985.17 EGG08275.1 - 0.0042 17.0 0.4 0.59 10.3 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat PI3_PI4_kinase PF00454.22 EGG08276.1 - 4.1e-26 91.9 0.3 3.7e-23 82.2 0.2 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PNP_UDP_1 PF01048.15 EGG08277.1 - 3.2e-11 42.6 0.1 1.6e-08 33.8 0.0 2.2 1 1 1 2 2 2 2 Phosphorylase superfamily Pmp3 PF01679.12 EGG08278.1 - 5.8e-28 96.3 5.5 6.4e-28 96.2 3.8 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 EGG08278.1 - 2 8.1 6.4 0.38 10.4 1.7 1.7 2 0 0 2 2 2 0 Conserved TM helix zf-C3HC4_2 PF13923.1 EGG08279.1 - 1.8e-09 37.4 19.4 7.4e-05 22.6 0.9 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG08279.1 - 2e-08 33.7 18.8 0.00025 20.6 0.8 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG08279.1 - 3.2e-08 33.0 18.2 3.7e-06 26.5 7.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGG08279.1 - 1.5e-07 31.1 17.8 5.6e-05 22.8 6.1 2.4 2 0 0 2 2 2 2 Ring finger domain Rtf2 PF04641.7 EGG08279.1 - 3.1e-06 26.5 4.3 0.00092 18.4 1.4 2.4 2 0 0 2 2 2 2 Rtf2 RING-finger zf-RING_5 PF14634.1 EGG08279.1 - 0.00012 21.7 11.0 0.00012 21.7 7.6 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGG08279.1 - 0.00046 20.0 14.9 0.045 13.6 4.8 2.9 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGG08279.1 - 0.0045 16.6 10.4 0.019 14.6 2.4 3.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EGG08279.1 - 0.82 9.3 17.9 0.044 13.3 4.5 3.3 2 2 1 3 3 3 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 EGG08279.1 - 1 9.2 19.1 2.3 8.1 7.2 2.8 2 2 0 2 2 2 0 FYVE zinc finger DUF2616 PF11077.3 EGG08279.1 - 2.3 7.6 5.1 0.39 10.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) Prok-RING_4 PF14447.1 EGG08279.1 - 2.8 7.5 12.3 0.13 11.7 2.9 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Sec6 PF06046.8 EGG08280.1 - 7.6e-20 70.5 0.5 1.2e-19 69.8 0.3 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 EGG08280.1 - 0.00092 18.0 4.1 0.012 14.3 0.5 2.2 2 0 0 2 2 2 2 Vps53-like, N-terminal Spc7 PF08317.6 EGG08280.1 - 0.025 13.2 7.4 0.3 9.6 0.1 2.4 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF2664 PF10867.3 EGG08280.1 - 0.41 11.2 5.6 1.7 9.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2664) Sec6 PF06046.8 EGG08281.1 - 2.5e-15 55.6 0.2 2.8e-15 55.4 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 MFS_1 PF07690.11 EGG08282.1 - 2.4e-07 29.7 16.6 2.4e-07 29.7 11.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3068 PF11271.3 EGG08285.1 - 3.9 6.4 8.2 48 2.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3068) Podoplanin PF05808.6 EGG08285.1 - 7.1 6.1 7.9 18 4.8 5.5 1.7 1 0 0 1 1 1 0 Podoplanin Paramyxo_ncap PF00973.14 EGG08285.1 - 9.1 4.8 10.9 18 3.8 7.6 1.4 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein F-box-like PF12937.2 EGG08287.1 - 1.5e-11 43.8 1.6 2.8e-11 42.9 1.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGG08287.1 - 4.1e-06 26.2 1.7 1.2e-05 24.8 1.2 1.7 1 0 0 1 1 1 1 F-box domain NUC173 PF08161.7 EGG08288.1 - 1.4e-32 112.6 1.0 4.6e-32 110.9 0.1 2.3 2 0 0 2 2 2 1 NUC173 domain RNA_pol_Rpb4 PF03874.11 EGG08290.1 - 0.039 13.9 0.0 0.088 12.8 0.0 1.7 1 1 0 1 1 1 0 RNA polymerase Rpb4 AAA_23 PF13476.1 EGG08292.1 - 4.5 7.5 7.3 9.3 6.5 1.3 2.3 2 1 0 2 2 2 0 AAA domain Maf PF02545.9 EGG08293.1 - 1e-36 125.8 0.0 1.5e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Maf-like protein Rapsyn_N PF10579.4 EGG08293.1 - 0.013 15.3 0.0 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region RPAP3_C PF13877.1 EGG08293.1 - 0.025 14.5 0.2 0.088 12.7 0.0 1.9 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 NOC3p PF07540.6 EGG08293.1 - 0.062 13.5 0.1 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Nucleolar complex-associated protein ADH_zinc_N PF00107.21 EGG08293.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SAM_1 PF00536.25 EGG08294.1 - 1.8e-10 40.8 0.1 4.2e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box PF00505.14 EGG08294.1 - 8.2e-09 35.6 0.0 2.1e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box SAM_2 PF07647.12 EGG08294.1 - 8.5e-08 31.9 0.3 2.1e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.5 EGG08294.1 - 1.7e-06 28.3 0.0 6.1e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 HMG-box domain TraH_2 PF06871.6 EGG08294.1 - 0.51 9.7 2.0 1.1 8.6 1.4 1.6 1 0 0 1 1 1 0 TraH_2 Trypan_PARP PF05887.6 EGG08294.1 - 1.9 8.2 10.4 5.3 6.8 7.2 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_pol_E_B PF04042.11 EGG08295.1 - 7.1e-43 146.2 0.0 1.3e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B zf-H2C2_2 PF13465.1 EGG08296.1 - 6.3e-06 26.2 0.6 6.3e-06 26.2 0.4 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EGG08296.1 - 0.00035 20.7 18.7 0.00066 19.8 0.5 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EGG08296.1 - 0.036 13.9 4.1 0.2 11.6 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EGG08296.1 - 0.061 13.6 1.4 0.061 13.6 0.9 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger RasGEF_N_2 PF14663.1 EGG08296.1 - 0.43 10.5 3.8 0.97 9.3 0.2 2.8 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Pkinase PF00069.20 EGG08298.1 - 1.6e-67 227.4 0.0 2.7e-67 226.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG08298.1 - 1.7e-42 145.2 0.0 2.9e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EGG08298.1 - 1.8e-17 63.4 0.1 1.8e-17 63.4 0.1 2.8 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EGG08298.1 - 5.3e-05 22.3 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGG08298.1 - 0.09 12.4 0.1 0.83 9.3 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2890 PF11081.3 EGG08301.1 - 0.0072 16.4 4.3 0.011 15.7 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) Nop14 PF04147.7 EGG08301.1 - 0.91 7.3 12.2 1.4 6.7 8.4 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EGG08301.1 - 3.3 6.8 11.9 4.6 6.4 8.2 1.1 1 0 0 1 1 1 0 SDA1 COesterase PF00135.23 EGG08302.1 - 7.8e-05 21.5 0.0 0.0001 21.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family RCC1_2 PF13540.1 EGG08304.1 - 0.0077 15.8 3.6 0.11 12.1 0.0 3.4 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Lustrin_cystein PF14625.1 EGG08304.1 - 0.049 13.7 0.9 7.4 6.7 0.0 3.1 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain PyrI_C PF02748.10 EGG08304.1 - 0.27 10.7 1.6 2.6 7.5 0.3 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF1886 PF09171.5 EGG08306.1 - 0.0084 15.1 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1886) CAP PF00188.21 EGG08311.1 - 1.6e-15 57.7 2.0 3.5e-15 56.5 0.1 2.2 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF2413 PF10310.4 EGG08311.1 - 0.57 8.9 4.6 0.75 8.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Cu-oxidase_3 PF07732.10 EGG08312.1 - 3.3e-42 142.9 0.6 3.1e-39 133.3 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG08312.1 - 5.2e-34 116.7 2.6 7.2e-28 96.8 0.0 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EGG08312.1 - 2.3e-23 82.8 0.0 1.3e-22 80.4 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase ApbE PF02424.10 EGG08312.1 - 0.036 13.3 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 ApbE family Aconitase PF00330.15 EGG08313.1 - 1.5e-77 261.0 0.2 6e-45 153.5 0.0 3.1 2 1 1 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGG08313.1 - 2.8e-21 76.0 0.0 2.2e-20 73.0 0.0 2.2 1 1 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 EGG08313.1 - 0.0026 16.4 0.0 0.0042 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Tim44 PF04280.10 EGG08314.1 - 2.9e-28 98.7 0.0 7.5e-28 97.3 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain COesterase PF00135.23 EGG08315.1 - 3.9e-77 260.1 0.0 5.3e-77 259.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Trp_syntA PF00290.15 EGG08316.1 - 2.1e-82 275.5 0.1 2.8e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EGG08316.1 - 7e-22 78.0 0.6 7e-22 78.0 0.4 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme PA PF02225.17 EGG08316.1 - 0.051 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 PA domain Trp_syntA PF00290.15 EGG08317.1 - 4.6e-82 274.4 0.7 7.3e-82 273.7 0.0 1.6 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 EGG08317.1 - 7.7e-43 146.8 2.2 1.4e-42 145.9 1.5 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_transf_22 PF03901.12 EGG08320.1 - 3.6e-26 92.1 14.6 4.8e-26 91.7 10.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ribosomal_S11 PF00411.14 EGG08321.1 - 3e-40 136.8 0.4 3.7e-40 136.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PAS_4 PF08448.5 EGG08322.1 - 0.048 13.7 2.5 0.058 13.4 1.5 1.4 1 1 0 1 1 1 0 PAS fold 4HBT PF03061.17 EGG08323.1 - 4.9e-05 23.3 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily DnaJ PF00226.26 EGG08324.1 - 1.3e-12 47.2 0.1 5.5e-12 45.2 0.0 2.2 1 0 0 1 1 1 1 DnaJ domain Consortin_C PF15281.1 EGG08324.1 - 0.23 10.9 1.0 0.51 9.8 0.2 2.0 2 0 0 2 2 2 0 Consortin C-terminus RVT_3 PF13456.1 EGG08325.1 - 6.6e-08 32.2 0.0 1.7e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like CorA PF01544.13 EGG08326.1 - 4.7e-25 88.2 2.5 5e-18 65.1 0.3 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Ribosomal_L35Ae PF01247.13 EGG08328.1 - 3.1e-40 135.8 0.6 3.5e-40 135.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae Methyltransf_20 PF12147.3 EGG08328.1 - 0.052 12.4 0.0 0.053 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Rep_fac_C PF08542.6 EGG08331.1 - 1.8e-18 66.2 0.1 5.7e-18 64.6 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.24 EGG08331.1 - 5.6e-18 65.4 0.0 9.9e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EGG08331.1 - 6.6e-15 55.1 0.0 2.5e-13 50.0 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EGG08331.1 - 1.2e-09 37.3 0.0 3.5e-09 35.8 0.0 1.8 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EGG08331.1 - 1.6e-08 34.7 0.1 1.6e-05 25.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGG08331.1 - 1.8e-07 31.0 0.0 4.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGG08331.1 - 2.1e-06 27.5 0.6 0.00023 20.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EGG08331.1 - 6.4e-06 25.3 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGG08331.1 - 1.2e-05 24.9 0.0 2.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 EGG08331.1 - 2.6e-05 23.2 0.0 3.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 EGG08331.1 - 0.00014 21.3 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGG08331.1 - 0.00028 20.9 0.0 0.0029 17.5 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 EGG08331.1 - 0.00041 19.9 0.2 0.0013 18.3 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EGG08331.1 - 0.00097 18.7 0.0 0.0027 17.2 0.0 1.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EGG08331.1 - 0.0027 17.3 0.0 0.045 13.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGG08331.1 - 0.0029 17.3 0.0 0.0097 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.24 EGG08331.1 - 0.003 17.0 0.2 0.077 12.4 0.0 2.3 1 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGG08331.1 - 0.0031 17.3 0.0 0.0087 15.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EGG08331.1 - 0.0033 16.9 0.0 0.84 9.0 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain DNA_pol3_delta PF06144.8 EGG08331.1 - 0.0039 16.7 0.1 0.0096 15.4 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_24 PF13479.1 EGG08331.1 - 0.0045 16.5 0.0 0.0093 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGG08331.1 - 0.0093 16.1 0.2 0.076 13.1 0.0 2.5 3 0 0 3 3 2 1 RNA helicase AAA_28 PF13521.1 EGG08331.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EGG08331.1 - 0.02 14.3 0.0 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.8 EGG08331.1 - 0.02 13.6 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 EGG08331.1 - 0.021 14.2 0.0 0.055 12.8 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGG08331.1 - 0.023 13.8 0.0 0.27 10.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EGG08331.1 - 0.025 15.3 0.0 0.046 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGG08331.1 - 0.029 14.7 1.0 0.099 12.9 0.1 2.3 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EGG08331.1 - 0.034 13.8 0.0 0.083 12.5 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase SNF2_N PF00176.18 EGG08331.1 - 0.037 12.8 0.0 0.51 9.0 0.0 2.3 1 1 1 2 2 2 0 SNF2 family N-terminal domain Imm36 PF15597.1 EGG08331.1 - 0.055 13.6 0.2 0.15 12.1 0.0 1.8 2 0 0 2 2 1 0 Immunity protein 36 DUF2075 PF09848.4 EGG08331.1 - 0.067 12.1 0.0 0.26 10.2 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EGG08331.1 - 0.11 11.6 0.4 5.5 6.1 0.0 2.5 1 1 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 EGG08331.1 - 0.16 12.2 0.7 1 9.6 0.0 2.6 3 2 0 3 3 2 0 ABC transporter Cytochrom_C1 PF02167.10 EGG08332.1 - 3.5e-85 285.1 0.0 4.4e-85 284.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EGG08332.1 - 0.00083 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EGG08332.1 - 0.028 15.2 0.1 0.083 13.7 0.1 2.0 2 1 0 2 2 2 0 Cytochrome c Glyco_hydro_38 PF01074.17 EGG08334.1 - 2e-76 256.8 0.0 3.7e-76 255.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EGG08334.1 - 7.2e-63 212.9 0.0 1.2e-62 212.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EGG08334.1 - 1.8e-28 98.5 0.2 5.3e-28 97.0 0.0 1.9 2 0 0 2 2 2 1 Alpha mannosidase, middle domain Cpn10 PF00166.16 EGG08335.1 - 0.63 10.0 6.4 0.15 11.9 1.8 1.9 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit Glyco_hydro_20 PF00728.17 EGG08336.1 - 3.5e-30 105.3 0.0 5.2e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain PBP PF01161.15 EGG08337.1 - 2.4e-11 43.6 0.2 3.9e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP PF01161.15 EGG08338.1 - 3.8e-10 39.8 0.2 6.1e-10 39.1 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein TM1586_NiRdase PF14512.1 EGG08340.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative TM nitroreductase p450 PF00067.17 EGG08341.1 - 4.8e-70 236.3 0.0 5.8e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 gag-asp_proteas PF13975.1 EGG08342.1 - 0.0088 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EGG08342.1 - 0.017 15.0 0.0 0.054 13.4 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGG08342.1 - 0.021 15.3 0.0 0.059 13.8 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DUF2408 PF10303.4 EGG08346.1 - 7e-48 162.1 1.1 6.6e-32 110.4 0.0 4.3 2 1 2 4 4 4 3 Protein of unknown function (DUF2408) DUF4631 PF15450.1 EGG08346.1 - 0.11 10.8 1.7 0.24 9.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4631) DUF2015 PF09435.5 EGG08347.1 - 5.2e-19 68.3 0.1 6e-19 68.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) TPR_12 PF13424.1 EGG08349.1 - 0.00015 21.6 0.2 0.58 10.1 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGG08349.1 - 0.00026 20.5 0.0 0.25 11.0 0.0 2.5 2 0 0 2 2 2 2 TPR repeat SHNi-TPR PF10516.4 EGG08349.1 - 0.0012 17.9 0.9 0.0023 17.1 0.1 1.9 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.12 EGG08349.1 - 0.0031 17.2 0.0 10 6.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGG08349.1 - 0.013 15.1 0.1 7.3 6.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NifQ PF04891.7 EGG08349.1 - 0.061 13.4 0.1 0.15 12.2 0.1 1.7 1 1 0 1 1 1 0 NifQ GEMIN8 PF15348.1 EGG08349.1 - 0.71 9.8 7.1 0.37 10.7 3.2 1.8 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 UDP-g_GGTase PF06427.6 EGG08350.1 - 5.9e-52 176.0 0.0 9.8e-52 175.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EGG08350.1 - 1.9e-05 24.1 0.0 4.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 Abhydrolase_6 PF12697.2 EGG08351.1 - 2.7e-07 30.7 0.0 4.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG08351.1 - 0.009 15.7 0.0 0.15 11.8 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG08351.1 - 0.11 12.0 0.3 0.42 10.1 0.2 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold PX PF00787.19 EGG08352.1 - 1.6e-19 69.7 0.1 5.2e-19 68.1 0.0 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EGG08352.1 - 9.8e-09 34.8 3.7 2.6e-05 23.6 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like FAM92 PF06730.6 EGG08352.1 - 0.00014 21.2 0.1 0.00034 20.0 0.1 1.6 1 0 0 1 1 1 1 FAM92 protein BAR PF03114.13 EGG08352.1 - 0.014 14.9 2.0 2.5 7.5 0.1 2.2 2 0 0 2 2 2 0 BAR domain LRR_4 PF12799.2 EGG08356.1 - 0.43 10.2 5.4 0.46 10.1 0.2 3.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF2570 PF10828.3 EGG08357.1 - 0.34 10.5 3.9 9.3 5.9 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Alpha_kinase PF02816.13 EGG08365.1 - 0.00015 21.5 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family Pro-NT_NN PF07421.6 EGG08366.1 - 0.039 13.4 0.1 0.063 12.7 0.1 1.2 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor SlyX PF04102.7 EGG08367.1 - 0.099 13.0 3.5 0.22 11.9 0.7 2.3 2 0 0 2 2 2 0 SlyX Spc7 PF08317.6 EGG08372.1 - 3.9e-11 42.2 13.0 1.3e-10 40.5 9.0 1.8 1 1 0 1 1 1 1 Spc7 kinetochore protein Aa_trans PF01490.13 EGG08376.1 - 2.6e-86 289.6 14.3 3e-86 289.4 9.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_C48 PF02902.14 EGG08377.1 - 4.7e-36 124.4 4.9 6.4e-36 124.0 3.4 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Orthopox_C10L PF07020.6 EGG08379.1 - 1.3 9.5 8.3 2.2 8.8 0.7 2.6 2 0 0 2 2 2 0 Orthopoxvirus C10L protein LrgB PF04172.11 EGG08380.1 - 8.1e-21 74.1 6.0 2.4e-20 72.6 0.3 2.3 2 0 0 2 2 2 2 LrgB-like family DUF3353 PF11833.3 EGG08380.1 - 0.21 11.0 0.8 0.7 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) zf-UBP PF02148.14 EGG08381.1 - 4.4e-21 74.7 3.6 1.4e-20 73.1 2.5 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.7 EGG08381.1 - 2.8e-14 52.6 0.0 6.2e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.1 EGG08381.1 - 7.9e-08 32.0 10.9 7.9e-08 32.0 7.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EGG08381.1 - 0.00023 20.7 8.5 0.00023 20.7 5.9 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGG08381.1 - 0.00028 20.9 8.3 0.00028 20.9 5.7 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGG08381.1 - 0.00029 20.4 16.5 0.0017 17.9 4.6 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG08381.1 - 0.00047 19.7 8.9 0.00047 19.7 6.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGG08381.1 - 0.00068 19.4 5.3 0.0016 18.2 3.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EGG08381.1 - 0.0025 17.8 9.6 0.0025 17.8 6.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGG08381.1 - 0.042 13.4 5.4 0.12 12.0 3.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain BAR_2 PF10455.4 EGG08383.1 - 0.00066 18.6 1.5 0.0007 18.6 1.1 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Nop25 PF09805.4 EGG08383.1 - 0.29 11.1 9.7 0.35 10.9 6.7 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DDHD PF02862.12 EGG08383.1 - 0.32 10.7 7.2 0.37 10.5 5.0 1.1 1 0 0 1 1 1 0 DDHD domain Sigma70_r1_2 PF00140.15 EGG08383.1 - 0.35 10.5 5.1 0.56 9.9 3.6 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 DUF2514 PF10721.4 EGG08383.1 - 0.52 10.0 6.0 0.61 9.7 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Macoilin PF09726.4 EGG08383.1 - 0.59 8.3 6.3 0.63 8.2 4.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1682 PF07946.9 EGG08383.1 - 2.3 6.9 8.8 2.7 6.7 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LRR_4 PF12799.2 EGG08389.1 - 0.017 14.7 6.2 3.8 7.2 0.1 4.5 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG08391.1 - 0.092 12.5 11.4 0.49 10.1 0.1 4.7 3 2 2 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EGG08391.1 - 0.11 12.5 1.7 12 6.3 0.0 4.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_4 PF12799.2 EGG08391.1 - 0.19 11.4 8.1 9.7 5.9 0.0 4.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGG08391.1 - 0.72 10.3 3.9 2.7e+02 2.5 0.0 5.2 6 0 0 6 6 6 0 Leucine rich repeat RhoGAP PF00620.22 EGG08395.1 - 1e-43 148.5 0.0 2.1e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EGG08395.1 - 3.5e-10 39.9 0.1 1.7e-09 37.6 0.1 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Toxin_4 PF00706.12 EGG08396.1 - 0.054 13.7 0.4 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Anenome neurotoxin MIP PF00230.15 EGG08397.1 - 7.2e-38 130.3 19.7 9.5e-38 129.9 13.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.15 EGG08398.1 - 5.8e-39 133.8 16.3 7.5e-39 133.5 11.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.15 EGG08399.1 - 8e-40 136.7 20.1 1.1e-39 136.2 13.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein LSM PF01423.17 EGG08400.1 - 6.8e-16 57.5 0.3 9.8e-16 57.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain NADH-u_ox-rdase PF10785.4 EGG08401.1 - 4.7e-26 90.8 0.2 7.2e-26 90.2 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EGG08401.1 - 4e-20 71.3 0.2 6.6e-20 70.6 0.1 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Pil1 PF13805.1 EGG08402.1 - 3.1e-31 108.5 4.3 3.1e-31 108.5 3.0 1.6 2 0 0 2 2 2 1 Eisosome component PIL1 V_ATPase_I PF01496.14 EGG08402.1 - 0.041 11.7 5.1 0.058 11.2 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 EGG08402.1 - 0.06 13.3 11.9 0.031 14.2 6.4 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.1 EGG08402.1 - 0.082 12.0 10.9 0.21 10.7 7.6 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spectrin PF00435.16 EGG08402.1 - 0.1 12.9 2.6 0.32 11.3 1.8 1.9 1 0 0 1 1 1 0 Spectrin repeat APG6 PF04111.7 EGG08402.1 - 0.1 11.6 8.5 0.081 11.9 3.5 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Cauli_AT PF03233.8 EGG08402.1 - 0.11 12.1 7.7 0.043 13.5 3.2 1.8 2 0 0 2 2 2 0 Aphid transmission protein Peptidase_C6 PF00851.13 EGG08402.1 - 0.11 11.0 1.6 0.35 9.4 0.7 1.8 2 0 0 2 2 2 0 Helper component proteinase DUF16 PF01519.11 EGG08402.1 - 0.3 11.3 6.0 0.84 9.8 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 Snapin_Pallidin PF14712.1 EGG08402.1 - 1.8 8.9 10.9 13 6.1 4.3 2.6 2 0 0 2 2 2 0 Snapin/Pallidin IncA PF04156.9 EGG08402.1 - 2.7 7.5 12.4 0.34 10.5 5.5 1.8 2 0 0 2 2 2 0 IncA protein DUF2935 PF11155.3 EGG08402.1 - 3.4 7.7 6.0 2.3 8.3 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) FemAB PF02388.11 EGG08402.1 - 6.5 5.3 10.1 2.6 6.6 4.2 2.2 3 0 0 3 3 3 0 FemAB family Het-C PF07217.6 EGG08407.1 - 3.7e-190 633.1 0.2 3.5e-178 593.6 0.0 2.2 2 0 0 2 2 2 2 Heterokaryon incompatibility protein Het-C Mg296 PF09644.5 EGG08408.1 - 0.00077 19.3 1.9 0.0064 16.3 0.1 3.0 3 0 0 3 3 3 1 Mg296 protein Translin PF01997.11 EGG08409.1 - 1.7e-49 168.1 0.4 2e-49 167.9 0.3 1.0 1 0 0 1 1 1 1 Translin family Pyrophosphatase PF00719.14 EGG08409.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Inorganic pyrophosphatase OPT PF03169.10 EGG08410.1 - 1.6e-139 466.2 35.5 2e-139 465.8 24.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pyr_redox_3 PF13738.1 EGG08412.1 - 5.9e-15 55.8 0.8 3.4e-14 53.3 0.6 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGG08412.1 - 4.9e-12 44.8 0.1 7e-07 27.8 0.1 2.4 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGG08412.1 - 2.1e-10 40.4 0.1 5.9e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGG08412.1 - 2.1e-09 37.5 0.0 0.00011 22.1 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGG08412.1 - 3e-07 29.6 0.2 2.1e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EGG08412.1 - 1.2e-06 27.6 0.3 1.3e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EGG08412.1 - 4.2e-06 27.0 3.9 0.0069 16.7 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGG08412.1 - 0.00033 20.4 0.3 0.0028 17.4 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EGG08412.1 - 0.00048 19.3 0.6 0.0011 18.1 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EGG08412.1 - 0.0013 18.4 3.5 0.0024 17.5 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EGG08412.1 - 0.0019 17.1 2.3 0.0036 16.1 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 EGG08412.1 - 0.0039 17.2 1.2 0.43 10.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EGG08412.1 - 0.007 15.4 1.6 0.076 12.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EGG08412.1 - 0.01 14.3 4.3 0.018 13.5 0.6 2.2 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EGG08412.1 - 0.014 14.2 2.2 0.081 11.7 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EGG08412.1 - 0.025 14.3 4.3 0.039 13.6 0.4 2.5 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 EGG08412.1 - 0.07 12.7 2.8 2.2 7.8 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HgmA PF04209.8 EGG08412.1 - 0.08 11.3 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Amino_oxidase PF01593.19 EGG08412.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF2890 PF11081.3 EGG08413.1 - 0.12 12.4 2.7 0.18 11.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF1180 PF06679.7 EGG08413.1 - 0.3 10.9 2.9 1.9 8.3 2.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Packaging_FI PF14000.1 EGG08413.1 - 0.37 10.9 3.6 0.59 10.3 2.5 1.3 1 0 0 1 1 1 0 DNA packaging protein FI DUF3356 PF11836.3 EGG08415.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3356) MRP-S25 PF13741.1 EGG08416.1 - 0.63 9.4 5.0 0.33 10.3 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S25 Aldo_ket_red PF00248.16 EGG08417.1 - 1.1e-42 145.8 0.0 1.2e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-RING_2 PF13639.1 EGG08418.1 - 9e-12 44.6 4.1 1.6e-11 43.8 2.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGG08418.1 - 9.6e-09 35.1 3.7 2.6e-08 33.7 2.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGG08418.1 - 1.5e-08 34.3 1.3 1.5e-08 34.3 0.9 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGG08418.1 - 2e-07 30.5 1.9 5.1e-07 29.2 1.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EGG08418.1 - 1.4e-06 27.9 4.8 3.7e-06 26.5 3.3 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGG08418.1 - 1.6e-06 27.6 8.2 8.9e-06 25.2 5.1 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG08418.1 - 4e-05 23.2 6.6 9.9e-05 21.9 4.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tropomyosin PF00261.15 EGG08418.1 - 0.0058 15.7 2.6 0.0058 15.7 1.8 1.9 2 0 0 2 2 2 1 Tropomyosin zf-RING_6 PF14835.1 EGG08418.1 - 0.01 15.6 1.3 0.01 15.6 0.9 1.8 2 0 0 2 2 1 0 zf-RING of BARD1-type protein CP12 PF02672.10 EGG08418.1 - 0.051 14.0 0.4 0.12 12.8 0.3 1.7 1 0 0 1 1 1 0 CP12 domain Reo_sigmaC PF04582.7 EGG08418.1 - 0.07 12.3 0.3 0.096 11.8 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein zf-rbx1 PF12678.2 EGG08418.1 - 0.089 12.9 9.5 0.65 10.1 6.8 2.5 1 1 1 2 2 2 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EGG08418.1 - 0.095 12.5 2.2 0.18 11.6 0.5 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGG08418.1 - 0.096 12.2 4.3 1.9 8.1 0.4 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.7 EGG08418.1 - 0.19 11.5 3.7 1.2 9.0 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbons Med9 PF07544.8 EGG08418.1 - 0.42 10.3 6.0 11 5.8 0.9 3.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 LIM PF00412.17 EGG08418.1 - 0.46 10.5 3.7 5.5 7.1 2.1 2.3 2 0 0 2 2 2 0 LIM domain DUF4404 PF14357.1 EGG08418.1 - 1.5 9.3 5.4 1.1 9.7 0.8 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) FYVE PF01363.16 EGG08418.1 - 4.5 7.2 7.8 12 5.9 5.0 2.0 1 1 0 1 1 1 0 FYVE zinc finger Prok-RING_4 PF14447.1 EGG08418.1 - 9.1 5.9 7.9 4.1 7.0 2.4 2.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DUF4164 PF13747.1 EGG08419.1 - 0.037 14.1 0.8 0.033 14.3 1.6 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) DUF342 PF03961.8 EGG08419.1 - 1.9 6.8 6.5 2.9 6.1 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Kinesin PF00225.18 EGG08420.1 - 3e-106 354.8 0.0 3.5e-106 354.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Ran_BP1 PF00638.13 EGG08422.1 - 4.6e-48 162.3 0.9 4.6e-48 162.3 0.6 1.8 2 1 0 2 2 2 1 RanBP1 domain WH1 PF00568.18 EGG08422.1 - 1.8e-05 24.4 0.2 7.2e-05 22.4 0.1 1.8 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 EGG08422.1 - 0.003 17.1 0.5 0.0047 16.5 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) TFIIA PF03153.8 EGG08424.1 - 6.9 6.4 19.4 13 5.5 13.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fibrillarin PF01269.12 EGG08425.1 - 2.6e-108 360.2 0.0 3.1e-108 360.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EGG08425.1 - 1.9e-05 24.2 0.0 2.7e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EGG08425.1 - 0.0025 17.4 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGG08425.1 - 0.038 13.5 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fork_head_N PF08430.7 EGG08426.1 - 0.05 13.9 1.0 0.11 12.9 0.7 1.6 1 0 0 1 1 1 0 Forkhead N-terminal region DUF2970 PF11174.3 EGG08426.1 - 0.2 11.2 0.0 19 4.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2970) SnoaL_2 PF12680.2 EGG08431.1 - 0.12 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Nop PF01798.13 EGG08433.1 - 7.8e-60 200.5 0.0 1.6e-59 199.4 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGG08433.1 - 7.4e-27 92.9 0.0 2.3e-26 91.3 0.0 1.8 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGG08433.1 - 2.2e-23 82.1 0.8 8.2e-23 80.3 0.5 2.1 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Lyase_1 PF00206.15 EGG08435.1 - 4.8e-22 78.5 0.0 7.2e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EGG08435.1 - 1.4e-14 53.8 0.0 3.6e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4089 PF13318.1 EGG08435.1 - 0.093 13.0 0.1 0.26 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) Adenylsucc_synt PF00709.16 EGG08436.1 - 5.4e-151 503.0 0.0 7e-151 502.6 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase HMG_box PF00505.14 EGG08439.1 - 0.072 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box zf-CCHC_4 PF14392.1 EGG08440.1 - 0.046 13.3 0.8 0.077 12.6 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4469 PF14734.1 EGG08441.1 - 0.06 13.2 0.2 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold NinB PF05772.7 EGG08441.1 - 0.52 9.9 2.4 0.38 10.3 0.2 1.7 2 0 0 2 2 2 0 NinB protein Asp-B-Hydro_N PF05279.6 EGG08441.1 - 4.6 7.0 10.9 5 6.9 7.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Dicty_REP PF05086.7 EGG08442.1 - 5.5 4.6 10.5 5.8 4.5 7.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MAP65_ASE1 PF03999.7 EGG08442.1 - 7.6 5.0 10.9 9.3 4.7 7.5 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ApbA_C PF08546.6 EGG08443.1 - 1.2e-29 102.7 0.0 1.9e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EGG08443.1 - 1.3e-10 40.9 0.0 2.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GrpE PF01025.14 EGG08444.1 - 0.088 12.3 0.4 0.98 8.9 0.0 2.6 3 0 0 3 3 3 0 GrpE HTH_9 PF08221.6 EGG08446.1 - 9.2e-20 70.2 5.7 2.8e-13 49.5 0.9 3.6 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 EGG08446.1 - 5.2e-14 52.3 4.7 8.1e-12 45.2 0.1 2.7 1 1 1 3 3 3 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 EGG08446.1 - 4.7e-07 29.2 5.9 2.3e-05 23.8 1.2 4.1 5 0 0 5 5 5 1 TFIIE alpha subunit RST PF12174.3 EGG08446.1 - 0.07 12.9 0.4 0.26 11.1 0.3 1.9 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain DUF3713 PF12506.3 EGG08447.1 - 0.039 14.0 0.7 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) DUF1682 PF07946.9 EGG08450.1 - 0.011 14.5 10.5 0.013 14.4 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CT47 PF15623.1 EGG08450.1 - 0.012 15.3 5.2 0.013 15.2 3.6 1.0 1 0 0 1 1 1 0 Cancer/testis gene family 47 PBP_sp32 PF07222.7 EGG08450.1 - 0.05 12.7 5.3 0.058 12.5 3.7 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 GAGA_bind PF06217.7 EGG08450.1 - 0.055 13.4 4.6 0.058 13.3 3.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 EGG08450.1 - 0.1 12.2 15.1 0.12 12.0 10.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 eIF3_subunit PF08597.5 EGG08450.1 - 0.51 9.8 17.5 0.65 9.5 12.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Vfa1 PF08432.5 EGG08450.1 - 0.52 10.3 13.2 0.64 10.0 9.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 EGG08450.1 - 0.53 8.2 5.9 0.59 8.0 4.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2149 PF09919.4 EGG08450.1 - 0.6 10.2 2.5 1.2 9.3 1.7 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) RNase_H2-Ydr279 PF09468.5 EGG08450.1 - 1.3 8.1 9.0 1.5 7.9 6.3 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DDHD PF02862.12 EGG08450.1 - 1.4 8.6 4.3 1.5 8.5 3.0 1.1 1 0 0 1 1 1 0 DDHD domain Fucose_iso_N2 PF07882.7 EGG08450.1 - 2.6 7.6 5.9 3.5 7.2 4.1 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain YqfQ PF14181.1 EGG08450.1 - 3.6 7.5 9.3 4.5 7.2 6.4 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF685 PF05085.7 EGG08455.1 - 0.2 10.6 1.4 0.27 10.2 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF685) Alpha_kinase PF02816.13 EGG08456.1 - 1.5e-21 76.9 0.1 1.4e-20 73.7 0.1 2.1 2 0 0 2 2 2 1 Alpha-kinase family DUF3531 PF12049.3 EGG08456.1 - 0.016 14.8 0.0 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3531) Cys_rich_CPCC PF14206.1 EGG08456.1 - 0.59 9.7 5.2 1.2 8.7 3.6 1.6 1 0 0 1 1 1 0 Cysteine-rich CPCC LRR_4 PF12799.2 EGG08461.1 - 0.065 12.8 15.2 3.7 7.2 0.0 5.7 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGG08461.1 - 0.68 10.3 2.9 55 4.6 0.0 4.3 4 1 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 EGG08462.1 - 0.043 13.4 7.3 7.8 6.2 0.0 5.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) FTH PF01827.22 EGG08462.1 - 0.061 12.9 0.2 0.61 9.6 0.1 2.3 2 0 0 2 2 2 0 FTH domain F-box-like PF12937.2 EGG08462.1 - 0.078 12.7 0.7 1.8 8.3 0.1 2.8 2 0 0 2 2 2 0 F-box-like Wound_ind PF08186.6 EGG08464.1 - 4.7 7.2 5.7 0.79 9.6 0.3 2.4 3 0 0 3 3 3 0 Wound-inducible basic protein family CdhD PF03599.11 EGG08468.1 - 0.036 12.5 0.1 0.11 10.9 0.0 1.7 2 0 0 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Ornatin PF02088.10 EGG08469.1 - 0.11 12.0 2.5 0.17 11.5 1.7 1.2 1 0 0 1 1 1 0 Ornatin MgtE PF01769.11 EGG08475.1 - 2.4e-30 105.5 22.9 5.2e-13 49.4 3.1 4.2 3 1 1 4 4 4 3 Divalent cation transporter DEAD PF00270.24 EGG08478.1 - 5.3e-41 139.9 1.0 5.3e-41 139.9 0.7 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG08478.1 - 4.5e-27 93.7 0.2 2.2e-26 91.5 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EGG08478.1 - 0.0011 18.7 0.1 0.0047 16.6 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 EGG08478.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EGG08478.1 - 0.013 14.7 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EGG08478.1 - 0.056 13.0 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.9 EGG08478.1 - 0.065 12.9 0.0 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_30 PF13604.1 EGG08478.1 - 0.15 11.6 1.1 0.39 10.2 0.1 2.3 3 0 0 3 3 3 0 AAA domain Gp_dh_C PF02800.15 EGG08479.1 - 0.037 13.4 0.1 0.05 13.0 0.1 1.3 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain BBS1 PF14779.1 EGG08482.1 - 0.0055 15.7 0.8 0.011 14.7 0.5 1.4 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 DUF4441 PF14536.1 EGG08482.1 - 7.2 6.6 12.2 2.9 7.8 0.2 3.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4441) Catalase PF00199.14 EGG08485.1 - 1.2e-44 152.6 0.1 1.3e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 Catalase FliS PF02561.9 EGG08486.1 - 0.021 14.6 0.1 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein FliS YtzH PF14165.1 EGG08486.1 - 0.14 12.3 1.7 4.1 7.6 0.5 2.9 2 0 0 2 2 2 0 YtzH-like protein HSF_DNA-bind PF00447.12 EGG08487.1 - 3.2e-21 75.4 0.1 3.5e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding HSF_DNA-bind PF00447.12 EGG08488.1 - 1.6e-06 28.2 0.0 2.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding ATG16 PF08614.6 EGG08488.1 - 0.03 14.1 0.7 0.034 13.9 0.5 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Tmemb_cc2 PF10267.4 EGG08488.1 - 0.031 12.8 0.1 0.031 12.8 0.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Nnf1 PF03980.9 EGG08488.1 - 0.051 13.5 0.8 0.071 13.1 0.5 1.3 1 0 0 1 1 1 0 Nnf1 TFIIS_C PF01096.13 EGG08490.1 - 4.5e-16 58.1 7.9 7.8e-16 57.4 0.6 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGG08490.1 - 0.00024 20.7 12.4 0.00051 19.6 1.6 3.1 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit VP_N-CPKC PF11475.3 EGG08490.1 - 0.00025 20.5 1.5 0.45 10.0 0.0 2.6 2 0 0 2 2 2 2 Virion protein N terminal domain DZR PF12773.2 EGG08490.1 - 0.00042 20.0 6.8 0.22 11.3 0.2 2.6 2 1 0 2 2 2 2 Double zinc ribbon Lar_restr_allev PF14354.1 EGG08490.1 - 0.001 19.3 5.5 0.02 15.1 0.4 3.1 2 1 1 3 3 3 1 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 EGG08490.1 - 0.0023 17.0 12.5 0.29 10.3 1.4 3.4 3 1 0 3 3 3 2 zinc-ribbon domain HypA PF01155.14 EGG08490.1 - 0.0056 16.3 6.1 0.1 12.2 0.1 3.0 1 1 1 2 2 2 1 Hydrogenase expression/synthesis hypA family IBR PF01485.16 EGG08490.1 - 0.0058 16.4 3.1 0.16 11.8 0.2 2.4 2 0 0 2 2 2 1 IBR domain zf-RING_3 PF14369.1 EGG08490.1 - 0.019 14.9 3.6 15 5.6 0.1 3.3 3 0 0 3 3 3 0 zinc-finger tRNA-synt_1f PF01921.13 EGG08490.1 - 0.024 13.2 0.0 0.034 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Rpr2 PF04032.11 EGG08490.1 - 0.026 14.3 0.7 0.026 14.3 0.5 2.6 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-H2C2_2 PF13465.1 EGG08490.1 - 0.03 14.6 0.5 0.03 14.6 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 EGG08490.1 - 0.033 14.1 10.8 0.91 9.5 0.7 3.6 3 1 0 3 3 3 0 Zinc ribbon domain Antiterm PF03589.8 EGG08490.1 - 0.034 14.2 1.4 2.6 8.1 0.0 2.5 1 1 0 2 2 2 0 Antitermination protein zinc_ribbon_2 PF13240.1 EGG08490.1 - 0.036 13.5 15.3 0.18 11.3 0.2 3.8 3 1 0 3 3 3 0 zinc-ribbon domain Terminase_GpA PF05876.7 EGG08490.1 - 0.039 12.3 1.6 0.058 11.7 0.6 1.6 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zf-ISL3 PF14690.1 EGG08490.1 - 0.042 13.8 5.0 7.8 6.6 0.3 3.4 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C4_Topoisom PF01396.14 EGG08490.1 - 0.046 13.2 10.6 5.6 6.5 0.1 3.7 4 0 0 4 4 3 0 Topoisomerase DNA binding C4 zinc finger Ogr_Delta PF04606.7 EGG08490.1 - 0.047 13.3 1.5 0.047 13.3 1.0 2.6 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger Vel1p PF10339.4 EGG08490.1 - 0.082 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Yeast-specific zinc responsive DUF2082 PF09855.4 EGG08490.1 - 0.09 12.6 8.8 11 5.9 0.2 3.6 4 0 0 4 4 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF2387 PF09526.5 EGG08490.1 - 0.1 12.5 5.4 0.24 11.3 0.3 2.8 2 1 1 3 3 2 0 Probable metal-binding protein (DUF2387) zf-C2H2_4 PF13894.1 EGG08490.1 - 0.1 12.9 8.0 0.36 11.2 0.7 3.6 4 0 0 4 4 3 0 C2H2-type zinc finger Baculo_LEF5_C PF11792.3 EGG08490.1 - 0.15 11.4 0.0 0.15 11.4 0.0 2.7 3 0 0 3 3 2 0 Baculoviridae late expression factor 5 C-terminal domain UPF0547 PF10571.4 EGG08490.1 - 0.18 11.4 0.7 0.18 11.4 0.5 3.5 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.1 EGG08490.1 - 0.19 11.4 7.2 23 4.7 0.1 4.1 4 0 0 4 4 4 0 Nudix N-terminal zf-CSL PF05207.8 EGG08490.1 - 0.28 10.7 0.1 0.28 10.7 0.1 3.2 3 1 1 4 4 4 0 CSL zinc finger Ribosomal_S27e PF01667.12 EGG08490.1 - 0.42 10.1 6.4 8.7 5.9 0.4 3.7 3 1 0 3 3 3 0 Ribosomal protein S27 C1_1 PF00130.17 EGG08490.1 - 0.46 10.2 0.1 0.46 10.2 0.1 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-TFIIB PF13453.1 EGG08490.1 - 0.62 9.2 7.5 0.093 11.9 1.3 2.4 2 1 0 2 2 2 0 Transcription factor zinc-finger zinc-ribbons_6 PF07191.7 EGG08490.1 - 0.74 9.6 6.7 6.3 6.6 1.5 2.7 2 1 0 2 2 2 0 zinc-ribbons Prok-RING_1 PF14446.1 EGG08490.1 - 1.1 9.0 8.5 14 5.4 0.8 3.4 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 ADK_lid PF05191.9 EGG08490.1 - 1.2 8.9 10.2 7 6.4 0.9 3.7 3 1 0 3 3 3 0 Adenylate kinase, active site lid TerY-C PF15616.1 EGG08490.1 - 1.5 8.7 8.6 2.8 7.8 0.2 2.8 1 1 1 2 2 2 0 TerY-C metal binding domain DUF1610 PF07754.6 EGG08490.1 - 1.9 8.6 13.5 1.3 9.1 0.5 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) zf-Mss51 PF13824.1 EGG08490.1 - 2 8.3 7.2 0.46 10.3 0.7 2.8 3 1 0 3 3 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Methyltransf_13 PF08421.6 EGG08490.1 - 2.1 7.9 7.8 1 8.8 0.0 3.4 4 0 0 4 4 4 0 Putative zinc binding domain Zn_Tnp_IS1595 PF12760.2 EGG08490.1 - 2.5 7.9 12.0 14 5.6 4.3 3.3 2 2 1 3 3 3 0 Transposase zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EGG08490.1 - 3 7.3 8.7 4.8 6.7 0.3 2.9 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit TF_Zn_Ribbon PF08271.7 EGG08490.1 - 3.2 7.1 13.3 3.1 7.2 0.4 3.6 3 1 0 3 3 3 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 EGG08490.1 - 3.4 7.2 13.6 25 4.4 0.1 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain zf-C2HC5 PF06221.8 EGG08490.1 - 3.4 7.4 9.5 1 9.1 0.4 3.1 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_5 PF13719.1 EGG08490.1 - 3.8 7.1 10.8 1.6 8.4 0.3 3.5 4 0 0 4 4 3 0 zinc-ribbon domain zf-AN1 PF01428.11 EGG08490.1 - 3.9 7.4 6.5 13 5.7 0.1 3.1 3 1 0 3 3 3 0 AN1-like Zinc finger zinc_ribbon_4 PF13717.1 EGG08490.1 - 4.5 7.0 10.6 1.5 8.5 0.2 3.5 4 0 0 4 4 3 0 zinc-ribbon domain CpXC PF14353.1 EGG08490.1 - 5.1 7.0 9.1 2.6 8.0 1.5 3.1 2 2 0 2 2 2 0 CpXC protein Auto_anti-p27 PF06677.7 EGG08490.1 - 6.3 6.6 12.0 0.85 9.4 0.2 3.5 4 0 0 4 4 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF3797 PF12677.2 EGG08490.1 - 7.3 6.3 13.9 8.8 6.0 0.1 3.9 2 2 2 4 4 4 0 Domain of unknown function (DUF3797) OrfB_Zn_ribbon PF07282.6 EGG08490.1 - 7.8 6.2 8.6 18 5.0 0.2 2.9 2 2 0 2 2 2 0 Putative transposase DNA-binding domain zf-C3HC4_4 PF15227.1 EGG08490.1 - 9 6.2 8.1 3.7 7.5 0.6 3.0 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Ribosomal_L32p PF01783.18 EGG08490.1 - 9.4 6.4 6.5 56 4.0 1.2 3.4 2 2 0 2 2 2 0 Ribosomal L32p protein family DUF1515 PF07439.6 EGG08492.1 - 0.0064 16.2 0.7 0.055 13.2 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1515) APG6 PF04111.7 EGG08492.1 - 0.37 9.7 5.4 0.68 8.9 3.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Zn_clus PF00172.13 EGG08494.1 - 0.47 10.3 7.1 3.1 7.7 1.4 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SNARE PF05739.14 EGG08496.1 - 0.0056 16.3 3.5 0.057 13.1 0.8 3.5 3 0 0 3 3 3 1 SNARE domain NPV_P10 PF05531.7 EGG08496.1 - 0.087 13.0 12.9 1.8 8.8 0.0 4.4 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 EGG08496.1 - 1.2 9.0 12.0 15 5.5 0.0 4.7 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1796 PF08795.5 EGG08496.1 - 1.5 8.4 6.1 4.1 7.0 0.0 3.5 3 0 0 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) DUF1664 PF07889.7 EGG08496.1 - 2.6 7.8 15.2 0.64 9.8 1.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) CCDC-167 PF15188.1 EGG08496.1 - 5.9 6.9 11.9 6 6.8 0.0 4.7 3 1 2 5 5 5 0 Coiled-coil domain-containing protein 167 DUF948 PF06103.6 EGG08496.1 - 7.2 6.5 11.6 2.1 8.2 0.7 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Zn_clus PF00172.13 EGG08497.1 - 0.93 9.4 6.6 16 5.4 2.2 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.26 EGG08498.1 - 2.9e-08 33.3 0.0 7.2e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.1 EGG08498.1 - 0.00026 20.8 0.2 0.89 9.5 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGG08498.1 - 0.00099 19.4 0.2 0.01 16.1 0.1 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG08498.1 - 0.0037 16.9 0.2 2.8 7.9 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGG08498.1 - 0.0068 16.3 0.1 1.5 8.8 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGG08498.1 - 0.016 15.0 0.3 0.86 9.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGG08498.1 - 0.052 13.1 0.4 0.14 11.7 0.3 1.7 1 1 0 1 1 1 0 TPR repeat TPR_6 PF13174.1 EGG08498.1 - 0.054 13.9 0.1 19 6.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGG08498.1 - 0.091 13.4 0.2 1.1 10.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DAO PF01266.19 EGG08500.1 - 6.4e-40 137.1 0.0 5.5e-39 134.0 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 EGG08500.1 - 4e-05 21.9 0.0 0.00074 17.8 0.0 2.5 3 0 0 3 3 3 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.1 EGG08500.1 - 0.00014 21.7 0.0 0.00046 20.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGG08500.1 - 0.018 13.9 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EGG08500.1 - 0.021 14.8 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGG08500.1 - 0.096 13.1 0.0 0.67 10.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MIP PF00230.15 EGG08501.1 - 2.2e-23 82.9 7.5 7e-23 81.2 5.2 1.7 1 1 0 1 1 1 1 Major intrinsic protein MMR_HSR1 PF01926.18 EGG08505.1 - 2.7e-12 46.6 0.0 6e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGG08505.1 - 0.00027 20.1 0.0 0.00051 19.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EGG08505.1 - 0.0026 17.0 0.1 0.01 15.1 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGG08505.1 - 0.0051 16.6 0.4 0.21 11.3 0.0 3.0 2 1 1 3 3 3 1 Dynamin family Miro PF08477.8 EGG08505.1 - 0.0058 17.1 0.6 0.014 15.8 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein DUF4085 PF13315.1 EGG08505.1 - 0.024 13.9 0.3 0.041 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) AAA_18 PF13238.1 EGG08505.1 - 0.057 13.7 0.3 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGG08505.1 - 0.12 13.1 0.1 0.52 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain bZIP_C PF12498.3 EGG08505.1 - 3.9 8.7 6.3 11 7.2 0.3 2.7 3 0 0 3 3 3 0 Basic leucine-zipper C terminal F-box-like PF12937.2 EGG08507.1 - 0.00048 19.7 0.0 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGG08507.1 - 0.012 15.2 0.2 1.2 8.9 0.0 2.8 2 0 0 2 2 2 0 F-box domain zf-CCHC_6 PF15288.1 EGG08508.1 - 0.3 10.7 1.2 0.59 9.8 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Cellulase PF00150.13 EGG08510.1 - 1.2e-37 129.6 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DPBB_1 PF03330.13 EGG08511.1 - 6.6e-09 35.6 0.2 7.8e-09 35.4 0.1 1.3 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGG08511.1 - 0.0019 17.8 0.2 0.0023 17.6 0.1 1.1 1 0 0 1 1 1 1 Barwin family C1_3 PF07649.7 EGG08511.1 - 0.72 9.9 2.9 28 4.8 0.0 3.1 3 0 0 3 3 3 0 C1-like domain DUF2461 PF09365.5 EGG08512.1 - 1.1e-60 204.6 0.0 1.9e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) RRN3 PF05327.6 EGG08512.1 - 1.8 6.5 11.3 3.1 5.7 7.8 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Tubulin PF00091.20 EGG08513.1 - 4e-70 235.9 0.0 6.5e-70 235.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGG08513.1 - 9.5e-49 164.6 0.1 1.5e-48 163.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EGG08513.1 - 1.1e-05 25.4 0.2 3.1e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EGG08513.1 - 0.0077 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Pox_Ag35 PF03286.9 EGG08514.1 - 0.082 12.4 4.0 0.17 11.3 2.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Curto_V2 PF07325.6 EGG08514.1 - 2.2 7.9 5.2 4 7.1 3.6 1.4 1 0 0 1 1 1 0 Curtovirus V2 protein DUF4486 PF14858.1 EGG08515.1 - 0.035 12.3 0.1 0.05 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) CHDCT2 PF08074.6 EGG08515.1 - 0.066 12.9 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain MAP65_ASE1 PF03999.7 EGG08515.1 - 1.2 7.6 8.2 1.9 6.9 5.7 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) GAS PF13851.1 EGG08517.1 - 0.084 12.0 1.1 0.11 11.6 0.1 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sen15 PF09631.5 EGG08519.1 - 4.5e-23 81.3 0.1 5.7e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein Pkinase PF00069.20 EGG08521.1 - 8.1e-72 241.4 0.1 2.3e-71 240.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG08521.1 - 3.6e-35 121.3 0.2 2.2e-32 112.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.14 EGG08521.1 - 7.7e-17 60.4 0.1 1.4e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EGG08521.1 - 9.7e-05 21.5 0.0 0.00019 20.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGG08521.1 - 0.0004 19.4 0.0 0.00067 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGG08521.1 - 0.0016 18.1 0.1 0.0099 15.6 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family WaaY PF06176.6 EGG08521.1 - 0.005 16.0 0.3 0.0097 15.1 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EGG08521.1 - 0.026 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EGG08521.1 - 0.15 11.6 0.5 0.47 9.9 0.3 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF1057 PF06342.7 EGG08523.1 - 0.096 11.4 0.0 0.33 9.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Chordopox_A13L PF05961.6 EGG08524.1 - 0.0015 18.3 0.1 0.0015 18.3 0.1 2.2 3 0 0 3 3 2 1 Chordopoxvirus A13L protein DUF3098 PF11297.3 EGG08524.1 - 0.0049 16.5 0.2 0.0049 16.5 0.2 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3098) Sigma_reg_N PF13800.1 EGG08524.1 - 0.039 13.9 0.1 0.039 13.9 0.0 2.2 2 1 1 3 3 3 0 Sigma factor regulator N-terminal DUF4597 PF15366.1 EGG08524.1 - 0.05 13.1 0.1 0.083 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) CbiQ PF02361.11 EGG08524.1 - 0.054 13.0 3.4 0.066 12.7 2.4 1.2 1 0 0 1 1 1 0 Cobalt transport protein Tetraspannin PF00335.15 EGG08524.1 - 0.056 12.7 0.0 0.056 12.7 0.0 1.9 2 0 0 2 2 2 0 Tetraspanin family DUF1616 PF07760.6 EGG08524.1 - 0.065 12.3 1.9 0.11 11.6 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1616) DUF1628 PF07790.6 EGG08524.1 - 0.085 13.6 0.6 0.33 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) RRXRR PF14239.1 EGG08524.1 - 0.16 11.3 4.4 0.21 10.9 3.1 1.1 1 0 0 1 1 1 0 RRXRR protein FtsX PF02687.16 EGG08524.1 - 0.39 10.4 9.6 0.62 9.8 6.7 1.3 1 0 0 1 1 1 0 FtsX-like permease family DUF1229 PF06797.6 EGG08524.1 - 0.45 9.2 7.1 0.63 8.8 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) DUF1509 PF07420.6 EGG08524.1 - 1.2 8.3 5.8 1.5 8.0 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) PrgI PF12666.2 EGG08524.1 - 3.9 7.6 6.0 14 5.8 4.2 1.9 1 1 0 1 1 1 0 PrgI family protein Glyco_hydro_61 PF03443.9 EGG08525.1 - 5e-23 82.0 2.9 5.8e-23 81.8 0.0 2.5 2 2 0 2 2 2 1 Glycosyl hydrolase family 61 CFEM PF05730.6 EGG08525.1 - 3.3e-05 23.6 10.6 3.3e-05 23.6 7.4 2.6 2 0 0 2 2 2 1 CFEM domain DM PF00751.13 EGG08525.1 - 2.2 7.8 11.2 2.7 7.6 0.2 2.5 2 0 0 2 2 2 0 DM DNA binding domain RIO1 PF01163.17 EGG08527.1 - 1.4e-45 154.9 0.1 1.4e-45 154.9 0.1 1.5 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.6 EGG08527.1 - 1.3e-33 114.9 0.0 2.8e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EGG08527.1 - 6.3e-09 35.9 2.3 2.4e-05 24.1 0.2 3.5 1 1 2 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EGG08527.1 - 2.3e-07 30.1 0.0 0.0063 15.6 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family TrmB PF01978.14 EGG08527.1 - 0.013 15.1 0.3 0.061 13.0 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 EGG08527.1 - 0.022 14.4 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.1 EGG08527.1 - 0.039 13.7 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_45 PF14947.1 EGG08527.1 - 0.096 12.5 0.0 2 8.3 0.0 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix Polysacc_synt_4 PF04669.8 EGG08529.1 - 2.2e-21 76.0 1.2 2.2e-20 72.8 0.9 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis PCI_Csn8 PF10075.4 EGG08530.1 - 7.2e-15 55.0 0.0 1.1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EGG08530.1 - 1.5e-12 47.5 0.0 2.1e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family adh_short PF00106.20 EGG08531.1 - 2.4e-30 105.6 0.3 2.4e-30 105.6 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG08531.1 - 6e-28 98.2 0.0 7.4e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG08531.1 - 4.6e-13 49.2 0.1 4.6e-13 49.2 0.0 1.5 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 EGG08531.1 - 3.6e-05 22.6 0.1 4.6e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGG08531.1 - 0.004 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Enoyl_reductase PF12241.3 EGG08531.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Abhydrolase_2 PF02230.11 EGG08533.1 - 2.1e-08 33.8 0.0 3.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase RRM_1 PF00076.17 EGG08534.1 - 6.6e-39 131.3 0.1 1.5e-23 82.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG08534.1 - 3.4e-27 94.2 0.1 8.3e-17 60.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EGG08534.1 - 5.1e-19 68.3 0.1 1.7e-18 66.6 0.1 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EGG08534.1 - 6.4e-15 54.7 0.1 1.2e-09 37.8 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGG08534.1 - 1.6e-05 24.6 0.7 5.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Mem_trans PF03547.13 EGG08534.1 - 0.57 8.4 4.5 1 7.5 3.1 1.5 1 1 0 1 1 1 0 Membrane transport protein GshA PF08886.6 EGG08536.1 - 0.076 11.3 0.0 0.079 11.2 0.0 1.0 1 0 0 1 1 1 0 Glutamate-cysteine ligase CDP-OH_P_transf PF01066.16 EGG08537.1 - 4.6e-11 42.9 0.0 5.3e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase CART PF06373.6 EGG08537.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) Ammonium_transp PF00909.16 EGG08538.1 - 1.6e-116 389.0 31.8 1.8e-116 388.8 22.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Glug PF07581.7 EGG08538.1 - 1.9 8.8 6.5 0.79 10.0 0.2 3.3 3 0 0 3 3 3 0 The GLUG motif DUF1754 PF08555.5 EGG08539.1 - 3.2e-12 46.8 4.5 3.2e-12 46.8 3.1 1.7 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) PAP1 PF08601.5 EGG08539.1 - 0.0071 16.0 7.1 0.0085 15.8 4.9 1.0 1 0 0 1 1 1 1 Transcription factor PAP1 PRCC PF10253.4 EGG08539.1 - 0.0074 17.0 3.6 0.0093 16.6 2.5 1.0 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting FUR PF01475.14 EGG08539.1 - 0.035 14.0 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family DUF2956 PF11169.3 EGG08539.1 - 0.042 13.8 5.8 1 9.3 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Tir_receptor_N PF07490.6 EGG08539.1 - 0.19 11.3 1.9 0.24 10.9 1.3 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus DUF334 PF03904.8 EGG08539.1 - 0.32 10.2 6.5 0.41 9.9 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) YjgP_YjgQ PF03739.9 EGG08539.1 - 0.36 9.5 1.2 0.42 9.3 0.8 1.0 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Peptidase_S64 PF08192.6 EGG08539.1 - 2.1 6.5 7.6 2.6 6.2 5.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3020 PF11223.3 EGG08540.1 - 0.95 9.9 6.0 2.3 8.6 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3020) WGG PF10273.4 EGG08541.1 - 2.1e-07 30.9 0.0 3.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 SAC3 PF12209.3 EGG08541.1 - 0.035 14.2 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain RRP7 PF12923.2 EGG08541.1 - 0.04 13.9 0.0 0.094 12.7 0.0 1.6 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) DnaJ-X PF14308.1 EGG08542.1 - 2.8e-38 131.2 1.9 4.9e-38 130.4 0.1 2.0 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EGG08542.1 - 7.9e-26 89.5 0.3 1.9e-25 88.3 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain zf-FCS PF06467.9 EGG08542.1 - 0.01 15.4 0.5 5.6 6.6 0.0 2.4 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_5 PF13719.1 EGG08542.1 - 0.023 14.2 0.5 5.5 6.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGG08542.1 - 0.057 13.1 0.9 5.8 6.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EGG08542.1 - 0.11 12.3 0.7 0.21 11.4 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon tRNA-synt_1b PF00579.20 EGG08543.1 - 2e-54 184.7 0.0 3.1e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Lipase_GDSL PF00657.17 EGG08544.1 - 2.8e-07 30.6 0.2 4.8e-07 29.8 0.1 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL PF00657.17 EGG08545.1 - 5.3e-10 39.5 0.9 8e-10 38.9 0.6 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EGG08545.1 - 0.00049 20.2 0.1 0.0022 18.1 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DUF2833 PF11090.3 EGG08547.1 - 0.013 15.6 0.4 0.033 14.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) PBP1_TM PF14812.1 EGG08548.1 - 0.0085 16.3 0.4 0.014 15.6 0.3 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal SAGA-Tad1 PF12767.2 EGG08548.1 - 0.041 13.5 2.9 0.064 12.9 2.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Ion_trans_2 PF07885.11 EGG08551.1 - 9.2e-32 108.6 28.3 8.5e-16 57.4 5.8 2.7 2 0 0 2 2 2 2 Ion channel DUF1345 PF07077.6 EGG08551.1 - 0.14 11.6 2.1 11 5.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) GET2 PF08690.5 EGG08552.1 - 0.17 11.0 6.1 0.45 9.7 2.8 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 Colicin_Pyocin PF01320.13 EGG08552.1 - 0.22 11.3 2.1 9.2 6.2 0.0 3.1 3 0 0 3 3 3 0 Colicin immunity protein / pyocin immunity protein Tmemb_cc2 PF10267.4 EGG08552.1 - 0.56 8.7 11.5 0.38 9.2 0.2 2.4 2 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein zf-CSL PF05207.8 EGG08553.1 - 1.1e-21 76.0 0.4 1.6e-21 75.5 0.3 1.3 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 EGG08553.1 - 0.0051 16.3 0.6 0.0072 15.8 0.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGG08553.1 - 0.013 15.1 0.7 0.021 14.4 0.5 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DUF164 PF02591.10 EGG08553.1 - 0.07 12.9 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative zinc ribbon domain Zn-ribbon_8 PF09723.5 EGG08553.1 - 0.1 12.5 0.3 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Dicty_CTDC PF00526.13 EGG08553.1 - 3.4 7.6 5.5 3.5 7.5 0.3 2.2 2 0 0 2 2 2 0 Dictyostelium (slime mold) repeat UPF0172 PF03665.8 EGG08555.1 - 8.6e-34 116.7 0.0 1.1e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 EGG08555.1 - 0.025 14.3 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Synaptobrevin PF00957.16 EGG08556.1 - 0.053 13.1 0.3 0.081 12.5 0.2 1.3 1 0 0 1 1 1 0 Synaptobrevin RskA PF10099.4 EGG08556.1 - 0.061 13.0 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA BatD PF13584.1 EGG08556.1 - 0.11 11.0 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance TMEM190 PF15431.1 EGG08556.1 - 0.15 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 190 Thiolase_N PF00108.18 EGG08559.1 - 7.7e-68 228.3 0.1 1.2e-67 227.7 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGG08559.1 - 1.7e-46 156.6 0.3 3.7e-46 155.5 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EGG08559.1 - 0.00037 20.4 0.0 0.0013 18.6 0.0 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 EGG08559.1 - 0.013 15.0 0.0 0.067 12.8 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EGG08559.1 - 0.028 13.8 0.1 0.062 12.7 0.1 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DUF3210 PF11489.3 EGG08560.1 - 0.41 9.2 5.9 0.63 8.6 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) Cellulase PF00150.13 EGG08561.1 - 1.6e-09 37.3 0.0 8.6e-09 35.0 0.0 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NIF PF03031.13 EGG08562.1 - 8.2e-52 175.0 0.0 1.1e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_like PF13242.1 EGG08563.1 - 0.00048 19.7 0.0 0.0005 19.7 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like PIG-P PF08510.7 EGG08563.1 - 0.14 11.7 0.5 0.23 11.1 0.3 1.2 1 0 0 1 1 1 0 PIG-P CH PF00307.26 EGG08564.1 - 1e-66 221.7 0.1 8.6e-17 61.1 0.4 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EGG08564.1 - 9e-07 28.9 0.1 2.3e-05 24.4 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGG08564.1 - 2.5e-06 26.3 0.2 0.051 12.8 0.0 3.6 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.3 EGG08564.1 - 2.7e-05 23.7 0.0 0.67 9.6 0.0 3.5 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 EGG08564.1 - 0.00083 19.0 0.2 0.26 11.2 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 EGG08564.1 - 0.015 14.5 2.4 0.17 11.3 0.0 3.5 3 0 0 3 3 3 0 EF hand adh_short PF00106.20 EGG08566.1 - 2.5e-63 212.9 7.2 7.2e-32 110.6 0.4 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EGG08566.1 - 2.3e-32 112.1 4.2 2.1e-17 63.3 0.3 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EGG08566.1 - 2.6e-25 88.1 0.0 5.3e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EGG08566.1 - 3.2e-06 26.9 0.0 3.4e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.13 EGG08566.1 - 7.6e-05 22.4 6.8 0.05 13.2 0.7 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EGG08566.1 - 0.00042 19.4 0.7 0.23 10.5 0.1 3.3 3 0 0 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3845 PF12956.2 EGG08566.1 - 0.1 11.9 0.3 2.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure adh_short PF00106.20 EGG08568.1 - 7.8e-62 208.0 8.6 2.7e-32 111.9 0.7 2.5 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EGG08568.1 - 4.7e-31 107.8 4.8 9.2e-18 64.5 0.5 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EGG08568.1 - 9e-26 89.6 0.0 1.9e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EGG08568.1 - 2.7e-07 30.4 0.0 5e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.13 EGG08568.1 - 0.00049 19.7 6.7 0.14 11.8 0.3 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EGG08568.1 - 0.023 13.7 1.2 2 7.4 0.1 2.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ribosomal_S10 PF00338.17 EGG08572.1 - 0.5 10.2 3.1 0.47 10.3 1.2 1.6 1 1 1 2 2 2 0 Ribosomal protein S10p/S20e PIP5K PF01504.13 EGG08575.1 - 1.1e-55 188.4 0.0 2.1e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EGG08575.1 - 2.4e-26 92.4 0.0 3.5e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EGG08575.1 - 1e-17 63.7 7.2 2e-17 62.8 5.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 EGG08575.1 - 0.69 9.8 7.2 1.9 8.4 3.1 2.7 3 0 0 3 3 3 0 IBR domain DICT PF10069.4 EGG08577.1 - 0.021 14.3 0.1 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Sensory domain found in DIguanylate Cyclases & Two-component systems DUF4451 PF14616.1 EGG08581.1 - 7.9e-31 106.4 0.3 2e-30 105.0 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) FSIP1 PF15554.1 EGG08581.1 - 0.92 8.2 6.4 1.6 7.4 4.4 1.4 1 0 0 1 1 1 0 FSIP1 family PRP3 PF08572.5 EGG08582.1 - 4.3e-63 212.6 4.8 4.3e-63 212.6 3.3 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EGG08582.1 - 1.3e-35 121.8 1.4 1.4e-35 121.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) BLUF PF04940.7 EGG08582.1 - 0.007 16.0 0.3 0.032 13.9 0.0 2.3 3 0 0 3 3 3 1 Sensors of blue-light using FAD Ribosomal_L6 PF00347.18 EGG08584.1 - 2.4e-26 92.0 4.4 2.7e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Rad60-SLD PF11976.3 EGG08585.1 - 1.1e-20 73.1 0.1 1.3e-20 72.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGG08585.1 - 2.4e-08 33.2 0.0 3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family FAR1 PF03101.10 EGG08587.1 - 0.0002 21.8 0.4 0.13 12.7 0.1 2.8 2 2 0 2 2 2 2 FAR1 DNA-binding domain DUF3129 PF11327.3 EGG08588.1 - 7.7e-39 133.4 7.4 1.2e-38 132.7 5.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Autophagy_N PF03986.8 EGG08589.1 - 3.6e-45 153.2 0.9 4.5e-45 153.0 0.1 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EGG08589.1 - 4.2e-27 94.1 0.6 8.3e-27 93.1 0.4 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EGG08589.1 - 3.9e-14 51.4 2.0 6.8e-14 50.6 1.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal CDO_I PF05995.7 EGG08590.1 - 0.069 12.3 0.1 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Cysteine dioxygenase type I Milton PF12448.3 EGG08591.1 - 8.3 6.5 11.5 0.13 12.3 1.8 2.4 2 0 0 2 2 2 0 Kinesin associated protein PIG-P PF08510.7 EGG08592.1 - 0.2 11.3 0.1 0.2 11.3 0.0 3.1 2 1 0 2 2 2 0 PIG-P LTV PF04180.9 EGG08593.1 - 0.0054 16.2 0.1 0.0078 15.7 0.1 1.2 1 0 0 1 1 1 1 Low temperature viability protein DUF4289 PF14121.1 EGG08593.1 - 0.063 11.6 0.0 0.087 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4289) NAP PF00956.13 EGG08594.1 - 1.1e-28 100.0 1.3 1.5e-28 99.5 0.9 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) CENP-B_dimeris PF09026.5 EGG08594.1 - 2.3 8.5 8.9 6.5 7.0 6.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DPBB_1 PF03330.13 EGG08595.1 - 0.03 14.3 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Carn_acyltransf PF00755.15 EGG08598.1 - 5e-163 543.3 0.0 8.5e-163 542.5 0.0 1.3 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase ICE2 PF08426.5 EGG08600.1 - 6.1e-62 209.5 28.6 3.4e-60 203.8 13.9 2.0 1 1 1 2 2 2 2 ICE2 Rhomboid PF01694.17 EGG08600.1 - 6.5 6.7 13.6 4.3 7.3 4.0 3.1 2 1 1 3 3 3 0 Rhomboid family TRAPPC9-Trs120 PF08626.6 EGG08601.1 - 3e-62 210.4 19.9 4e-61 206.6 13.8 2.7 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_11 PF13414.1 EGG08601.1 - 0.002 17.7 0.0 0.39 10.3 0.0 2.3 2 0 0 2 2 2 2 TPR repeat Transglut_C PF00927.17 EGG08601.1 - 0.0073 16.3 0.0 0.041 13.9 0.0 2.3 2 0 0 2 2 2 1 Transglutaminase family, C-terminal ig like domain AAT PF03417.11 EGG08601.1 - 0.029 13.8 0.2 0.062 12.7 0.2 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TPR_12 PF13424.1 EGG08601.1 - 0.071 13.0 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGG08601.1 - 0.15 11.7 0.0 0.5 10.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PIN_4 PF13638.1 EGG08603.1 - 1.2e-06 28.6 0.3 4.7e-06 26.7 0.0 2.2 3 0 0 3 3 3 1 PIN domain GTP_EFTU PF00009.22 EGG08604.1 - 1.1e-56 191.3 0.1 2e-56 190.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGG08604.1 - 4e-33 113.5 0.1 1.1e-32 112.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EGG08604.1 - 7e-31 105.9 0.2 2.4e-30 104.1 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 EGG08604.1 - 4.9e-23 80.8 0.0 1.2e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGG08604.1 - 3.9e-14 52.5 0.1 1.3e-13 50.8 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 HSA PF07529.8 EGG08606.1 - 1.1e-14 53.8 3.8 1.1e-14 53.8 2.6 4.2 3 1 0 3 3 3 1 HSA Pal1 PF08316.6 EGG08606.1 - 0.76 10.2 10.6 4.7 7.6 7.3 2.4 1 0 0 1 1 1 0 Pal1 cell morphology protein Ycf1 PF05758.7 EGG08606.1 - 3 5.4 20.4 7 4.2 14.1 1.5 1 0 0 1 1 1 0 Ycf1 EIIBC-GUT_N PF03612.9 EGG08606.1 - 9.1 5.8 10.6 25 4.4 7.4 1.8 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Med31 PF05669.7 EGG08607.1 - 1.5e-28 98.5 1.9 1.8e-28 98.3 1.3 1.1 1 0 0 1 1 1 1 SOH1 DNA_binding_2 PF13724.1 EGG08608.1 - 0.012 15.7 0.0 0.012 15.7 0.0 3.0 2 1 0 2 2 2 0 DNA-binding domain KIAA1328 PF15369.1 EGG08608.1 - 2.8 7.6 6.6 3.5 7.3 4.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Ndc1_Nup PF09531.5 EGG08608.1 - 5 5.4 13.6 6.4 5.0 9.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RAP1 PF07218.6 EGG08608.1 - 7.2 4.5 15.0 8.8 4.2 10.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DAHP_synth_1 PF00793.15 EGG08609.1 - 5.4e-95 317.1 0.0 6.7e-95 316.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MPC PF03650.8 EGG08610.1 - 4.5e-33 113.7 0.6 5.4e-33 113.4 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MPC PF03650.8 EGG08611.1 - 1.1e-34 118.8 0.4 1.3e-34 118.6 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Tox-MPTase3 PF15639.1 EGG08617.1 - 0.0046 16.7 0.2 0.0086 15.8 0.1 1.4 1 0 0 1 1 1 1 Metallopeptidase toxin 3 Lipase_GDSL PF00657.17 EGG08619.1 - 5.5e-06 26.3 0.4 8e-06 25.8 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EGG08619.1 - 0.03 14.4 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ApoB100_C PF12491.3 EGG08619.1 - 0.099 12.2 0.3 0.74 9.5 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal Scm3 PF10384.4 EGG08620.1 - 6.5e-07 28.7 2.4 1.2e-06 27.9 0.8 2.1 2 0 0 2 2 2 1 Centromere protein Scm3 zf-CCHC PF00098.18 EGG08625.1 - 3.9e-05 23.3 0.9 7.4e-05 22.4 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle CIA30 PF08547.7 EGG08627.1 - 2e-29 102.4 0.0 2.6e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) ADC PF06314.6 EGG08628.1 - 5.7e-07 29.1 0.0 8.4e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) PhnI PF05861.7 EGG08630.1 - 0.011 14.3 0.3 0.013 14.0 0.2 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) 4F5 PF04419.9 EGG08630.1 - 0.023 15.4 1.8 3 8.6 0.1 2.6 2 0 0 2 2 2 0 4F5 protein family DUF4407 PF14362.1 EGG08630.1 - 0.12 11.2 1.8 0.15 10.9 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.4 EGG08630.1 - 0.31 9.2 4.0 0.33 9.1 2.8 1.0 1 0 0 1 1 1 0 Transmembrane protein FAM104 PF15434.1 EGG08630.1 - 1 9.5 9.1 4.8 7.4 1.4 2.3 1 1 1 2 2 2 0 Family 104 NST1 PF13945.1 EGG08630.1 - 1.6 8.7 5.5 2.4 8.1 3.8 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Herpes_UL32 PF06070.6 EGG08630.1 - 2.7 6.3 13.4 3.3 6.0 9.3 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Kinesin PF00225.18 EGG08631.1 - 1.2e-104 349.6 0.8 5.1e-104 347.5 0.0 2.4 2 0 0 2 2 2 1 Kinesin motor domain Baculo_PEP_C PF04513.7 EGG08631.1 - 1.2 8.9 26.6 0.9 9.3 0.1 6.0 5 2 2 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-ZPR1 PF03367.8 EGG08633.1 - 5.8e-103 340.9 0.9 4.3e-52 175.5 0.0 2.4 2 1 0 2 2 2 2 ZPR1 zinc-finger domain zf-ribbon_3 PF13248.1 EGG08633.1 - 0.0012 18.0 3.7 0.039 13.1 0.0 3.2 3 1 0 3 3 3 1 zinc-ribbon domain HypA PF01155.14 EGG08633.1 - 0.0098 15.5 1.4 4.1 7.1 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EGG08633.1 - 0.021 14.7 2.9 39 4.2 0.0 4.1 4 0 0 4 4 4 0 Zinc ribbon domain DUF3716 PF12511.3 EGG08633.1 - 0.32 10.6 0.1 0.32 10.6 0.1 2.2 2 1 2 4 4 4 0 Protein of unknown function (DUF3716) DZR PF12773.2 EGG08633.1 - 0.6 9.9 7.7 0.99 9.2 0.1 3.1 2 1 0 2 2 2 0 Double zinc ribbon UPF0547 PF10571.4 EGG08633.1 - 0.7 9.6 4.6 19 5.0 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 E7 PF00527.13 EGG08633.1 - 0.78 9.9 4.4 1.9 8.6 0.0 3.1 2 1 0 2 2 2 0 E7 protein, Early protein zinc_ribbon_2 PF13240.1 EGG08633.1 - 6.8 6.3 13.6 10 5.7 1.4 3.7 3 1 0 3 3 3 0 zinc-ribbon domain DUF4231 PF14015.1 EGG08635.1 - 7.6 6.5 7.2 0.68 9.9 0.8 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) CDK2AP PF09806.4 EGG08636.1 - 0.26 11.5 4.0 0.29 11.3 2.8 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3446 PF11928.3 EGG08636.1 - 2.9 8.1 12.0 0.38 10.9 4.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) FGGY_N PF00370.16 EGG08637.1 - 1e-11 44.6 0.1 3.7e-08 33.0 0.0 3.1 3 0 0 3 3 3 3 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EGG08637.1 - 0.0015 18.1 0.1 0.0049 16.5 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DPBB_1 PF03330.13 EGG08638.1 - 8.5e-07 28.8 4.0 9.8e-07 28.6 0.6 2.5 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Zip PF02535.17 EGG08638.1 - 0.014 14.4 1.7 0.018 14.0 0.9 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter Barwin PF00967.12 EGG08638.1 - 0.025 14.2 0.3 0.044 13.4 0.1 1.5 1 1 0 1 1 1 0 Barwin family DREPP PF05558.7 EGG08638.1 - 0.037 13.8 1.3 0.055 13.3 0.9 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide DPBB_1 PF03330.13 EGG08639.1 - 1e-08 35.0 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGG08639.1 - 0.0018 17.9 0.1 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Barwin family PPR_2 PF13041.1 EGG08640.1 - 5.3e-20 71.1 0.1 5.5e-08 32.6 0.0 5.1 2 2 4 6 6 6 4 PPR repeat family PPR_1 PF12854.2 EGG08640.1 - 4.8e-14 51.5 1.3 0.00016 21.0 0.0 5.3 5 1 0 5 5 5 3 PPR repeat PPR PF01535.15 EGG08640.1 - 5.4e-12 44.8 6.8 0.16 12.0 0.1 7.5 7 1 0 7 7 7 3 PPR repeat PPR_3 PF13812.1 EGG08640.1 - 7e-10 38.4 0.6 0.12 12.6 0.0 5.4 5 1 0 5 5 5 3 Pentatricopeptide repeat domain GatB_Yqey PF02637.13 EGG08640.1 - 0.061 13.0 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 GatB domain Inhibitor_I29 PF08246.7 EGG08640.1 - 0.25 11.6 1.2 2.4 8.5 0.2 2.2 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) Macoilin PF09726.4 EGG08641.1 - 0.066 11.4 1.3 0.066 11.4 0.9 1.0 1 0 0 1 1 1 0 Transmembrane protein HCO3_cotransp PF00955.16 EGG08643.1 - 4.5e-45 154.2 10.3 1.2e-26 93.4 2.3 2.2 1 1 1 2 2 2 2 HCO3- transporter family ANAPC15 PF15243.1 EGG08648.1 - 0.07 13.1 1.7 0.091 12.8 1.2 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 ETRAMP PF09716.5 EGG08648.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2076 PF09849.4 EGG08650.1 - 6.9 6.6 9.0 7.9 6.4 6.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Zn_clus PF00172.13 EGG08651.1 - 3.9e-05 23.4 2.8 5.5e-05 22.9 2.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.4 EGG08651.1 - 0.14 10.7 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein KIF1B PF12423.3 EGG08651.1 - 0.17 11.9 0.4 0.45 10.5 0.3 1.7 1 0 0 1 1 1 0 Kinesin protein 1B Sec3_C PF09763.4 EGG08652.1 - 0.0009 17.5 1.4 0.0012 17.0 1.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 ADIP PF11559.3 EGG08652.1 - 0.011 15.6 1.8 0.028 14.3 0.5 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 EGG08652.1 - 0.012 15.3 1.5 0.89 9.4 0.7 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Tropomyosin PF00261.15 EGG08652.1 - 0.023 13.7 4.4 0.033 13.2 3.1 1.3 1 0 0 1 1 1 0 Tropomyosin IncA PF04156.9 EGG08652.1 - 0.049 13.2 1.8 0.056 13.0 1.2 1.2 1 0 0 1 1 1 0 IncA protein Baculo_PEP_C PF04513.7 EGG08652.1 - 0.058 13.2 0.2 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG5 PF10392.4 EGG08652.1 - 0.1 12.5 0.7 0.2 11.6 0.5 1.4 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Mnd1 PF03962.10 EGG08652.1 - 0.14 11.8 2.9 0.22 11.1 2.0 1.2 1 0 0 1 1 1 0 Mnd1 family ATG16 PF08614.6 EGG08652.1 - 0.4 10.4 5.6 0.3 10.8 1.9 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.7 EGG08652.1 - 2.7 8.4 7.0 6.5 7.2 1.2 2.3 1 1 1 2 2 2 0 SlyX Capsule_synth PF05159.9 EGG08653.1 - 0.0037 16.7 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein DDE_3 PF13358.1 EGG08653.1 - 0.073 12.8 1.0 0.28 10.9 0.7 1.9 1 1 0 1 1 1 0 DDE superfamily endonuclease DUF4106 PF13388.1 EGG08654.1 - 0.0046 15.9 6.4 0.0046 15.9 4.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) FAM47 PF14642.1 EGG08655.1 - 0.017 14.4 5.7 0.021 14.0 3.9 1.2 1 0 0 1 1 1 0 FAM47 family ABC2_membrane PF01061.19 EGG08656.1 - 3.5e-47 160.2 16.4 5.2e-47 159.7 11.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGG08656.1 - 6.1e-24 84.8 0.1 9.9e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EGG08656.1 - 9.9e-06 24.8 18.5 9.9e-06 24.8 12.8 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 EGG08656.1 - 0.00013 22.0 0.7 0.43 10.4 0.6 2.5 1 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGG08656.1 - 0.00023 20.3 0.1 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGG08656.1 - 0.00055 20.7 0.0 0.0011 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGG08656.1 - 0.00062 19.2 0.0 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGG08656.1 - 0.0008 19.7 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGG08656.1 - 0.0027 17.8 0.3 0.046 13.8 0.4 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGG08656.1 - 0.0028 17.6 0.1 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EGG08656.1 - 0.0048 16.8 0.1 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EGG08656.1 - 0.0071 15.4 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EGG08656.1 - 0.013 15.0 0.3 0.031 13.7 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0079 PF02367.12 EGG08656.1 - 0.032 13.8 0.2 0.07 12.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EGG08656.1 - 0.035 13.8 0.0 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EGG08656.1 - 0.047 13.3 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 EGG08656.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EGG08656.1 - 0.1 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EGG08656.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP-synt_ab PF00006.20 EGG08656.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 EGG08656.1 - 0.13 12.0 0.2 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 NTPase ArgK PF03308.11 EGG08656.1 - 0.14 10.8 0.2 0.23 10.1 0.1 1.3 1 0 0 1 1 1 0 ArgK protein T2SE PF00437.15 EGG08656.1 - 0.17 10.7 0.6 0.27 10.0 0.4 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 EGG08656.1 - 0.17 11.3 0.1 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EGG08656.1 - 0.18 11.3 0.1 0.32 10.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EGG08658.1 - 6.7e-58 190.6 29.8 1.1e-11 44.0 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGG08658.1 - 1.7e-07 30.6 0.2 0.056 12.9 0.0 4.8 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EGG08658.1 - 0.0002 20.2 1.1 0.00056 18.8 0.3 1.8 1 1 1 2 2 2 1 Coatomer WD associated region JAB PF01398.16 EGG08659.1 - 0.0017 18.0 0.0 0.004 16.8 0.0 1.6 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Nop14 PF04147.7 EGG08661.1 - 0.4 8.5 21.4 0.42 8.4 14.8 1.0 1 0 0 1 1 1 0 Nop14-like family Menin PF05053.8 EGG08661.1 - 0.55 8.3 7.9 0.61 8.1 5.5 1.1 1 0 0 1 1 1 0 Menin BUD22 PF09073.5 EGG08661.1 - 0.87 8.5 22.9 1 8.3 15.9 1.1 1 0 0 1 1 1 0 BUD22 DUF572 PF04502.8 EGG08661.1 - 2.7 7.1 8.7 3.3 6.8 6.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF605 PF04652.11 EGG08661.1 - 4.7 6.5 16.6 5.7 6.2 11.5 1.2 1 0 0 1 1 1 0 Vta1 like FLO_LFY PF01698.11 EGG08661.1 - 8 5.1 7.4 10 4.8 5.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Macoilin PF09726.4 EGG08661.1 - 9.5 4.3 10.4 11 4.1 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2937 PF11157.3 EGG08663.1 - 0.11 11.8 0.1 0.43 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Sad1_UNC PF07738.8 EGG08664.1 - 9.6e-27 93.4 0.0 1.5e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal PDEase_II PF02112.10 EGG08667.1 - 9.3e-42 143.1 0.7 1.7e-41 142.2 0.5 1.4 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EGG08667.1 - 1.4e-05 24.7 0.0 2.5e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGG08667.1 - 0.014 15.0 0.6 0.095 12.3 0.4 2.1 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Glyco_hydro_71 PF03659.9 EGG08669.1 - 9.2e-94 314.0 4.2 1.1e-93 313.8 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 UPF0227 PF05728.7 EGG08671.1 - 0.089 12.5 0.3 0.21 11.2 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) zf-C2H2 PF00096.21 EGG08673.1 - 3.7e-11 42.6 3.2 4.6e-05 23.5 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG08673.1 - 4.1e-07 29.9 12.3 6e-07 29.4 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGG08673.1 - 3.5e-06 26.9 9.2 0.013 15.7 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGG08673.1 - 0.001 18.8 2.2 0.0024 17.6 1.6 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGG08673.1 - 0.0043 17.1 6.1 0.049 13.7 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-UBP PF02148.14 EGG08673.1 - 0.48 10.5 10.7 18 5.4 0.3 2.3 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-met PF12874.2 EGG08673.1 - 0.53 10.5 6.2 1.4 9.1 0.3 3.0 2 1 0 2 2 2 0 Zinc-finger of C2H2 type Sfi1 PF08457.5 EGG08675.1 - 2.2e-15 56.0 97.7 1.6e-13 49.9 31.6 4.2 1 1 2 3 3 3 3 Sfi1 spindle body protein TP53IP5 PF15331.1 EGG08677.1 - 0.14 12.0 4.5 0.19 11.6 3.1 1.3 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 FdhE PF04216.7 EGG08677.1 - 0.23 11.1 6.1 0.098 12.3 1.0 2.0 1 1 0 2 2 2 0 Protein involved in formate dehydrogenase formation FTA4 PF13093.1 EGG08677.1 - 2.2 7.6 7.9 4.2 6.7 5.4 1.6 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 UBN2_3 PF14244.1 EGG08679.1 - 8.7e-05 22.1 0.2 0.0013 18.2 0.2 2.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG08679.1 - 0.0003 20.3 0.1 0.00059 19.3 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGG08679.1 - 0.00031 20.5 0.1 0.00055 19.7 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type WD40 PF00400.27 EGG08680.1 - 8.7e-47 155.4 13.9 2e-09 36.9 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Striatin PF08232.7 EGG08680.1 - 4.4e-26 91.8 34.6 3.3e-24 85.7 0.0 4.7 4 0 0 4 4 4 2 Striatin family PAT1 PF09770.4 EGG08680.1 - 1.5 7.0 82.0 0.12 10.5 41.8 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 LRR_4 PF12799.2 EGG08681.1 - 0.041 13.5 3.3 1.2 8.8 0.1 3.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) PPTA PF01239.17 EGG08682.1 - 2.9e-31 105.4 20.4 9.2e-10 37.4 0.3 5.3 6 0 0 6 6 6 4 Protein prenyltransferase alpha subunit repeat DUF1399 PF07173.7 EGG08688.1 - 1.2e-10 41.8 0.2 7.5e-10 39.2 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1399) Aminotran_1_2 PF00155.16 EGG08688.1 - 1.1e-09 37.7 0.0 2e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Ndc1_Nup PF09531.5 EGG08692.1 - 4.8 5.4 5.9 5.3 5.3 4.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Corona_nucleoca PF00937.13 EGG08692.1 - 8.1 5.2 14.0 12 4.7 9.7 1.4 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4300 PF14133.1 EGG08694.1 - 0.21 10.8 1.7 0.3 10.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) RPAP2_Rtr1 PF04181.8 EGG08694.1 - 2.8 8.1 7.2 0.13 12.3 0.5 2.0 2 1 0 2 2 2 0 Rtr1/RPAP2 family DUF2913 PF11140.3 EGG08700.1 - 0.0033 16.7 0.3 0.0049 16.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2913) DUF2347 PF09804.4 EGG08700.1 - 0.007 15.6 0.4 0.01 15.1 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) TrbI_Ftype PF09677.5 EGG08700.1 - 0.026 14.3 1.2 0.068 13.0 0.3 2.0 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) VHS PF00790.14 EGG08700.1 - 0.048 13.2 0.3 0.098 12.2 0.2 1.5 1 0 0 1 1 1 0 VHS domain SE PF08491.5 EGG08701.1 - 1e-92 309.8 0.0 3.1e-92 308.3 0.0 1.7 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EGG08701.1 - 6.9e-08 31.7 0.0 7.3e-05 21.8 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGG08701.1 - 4.8e-05 22.4 0.0 0.0075 15.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.14 EGG08701.1 - 0.00016 20.8 0.1 0.2 10.6 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EGG08701.1 - 0.00059 19.7 0.0 0.0018 18.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EGG08701.1 - 0.0087 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EGG08701.1 - 0.02 13.7 0.0 0.18 10.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 EGG08701.1 - 0.028 13.0 0.0 0.12 10.9 0.0 2.0 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EGG08701.1 - 0.06 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGG08701.1 - 0.073 12.8 0.0 0.39 10.4 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 EGG08701.1 - 0.086 11.6 0.0 1.8 7.3 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 EGG08701.1 - 0.16 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pribosyltran_N PF13793.1 EGG08702.1 - 3.1e-45 152.6 0.0 4.1e-44 149.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGG08702.1 - 3.2e-33 115.0 0.1 6.2e-33 114.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGG08702.1 - 2.2e-14 53.2 0.1 5.6e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGG08702.1 - 0.0018 17.5 0.1 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Tetraspannin PF00335.15 EGG08704.1 - 7.2 5.8 8.2 9 5.5 5.7 1.2 1 0 0 1 1 1 0 Tetraspanin family F-box-like PF12937.2 EGG08705.1 - 0.0015 18.2 0.6 0.0027 17.3 0.4 1.5 1 0 0 1 1 1 1 F-box-like TRC8_N PF13705.1 EGG08705.1 - 0.018 13.6 0.2 0.026 13.1 0.1 1.1 1 0 0 1 1 1 0 TRC8 N-terminal domain Asp PF00026.18 EGG08706.1 - 3e-48 164.6 3.5 3e-48 164.6 2.4 2.2 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGG08706.1 - 0.0061 17.0 1.6 0.077 13.5 0.2 3.1 2 1 0 2 2 2 1 Aspartyl protease Phage_int_SAM_4 PF13495.1 EGG08708.1 - 0.02 15.1 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Cyclase_polyket PF04673.7 EGG08709.1 - 0.1 12.6 1.6 1.7 8.7 0.1 2.7 2 0 0 2 2 2 0 Polyketide synthesis cyclase BolA PF01722.13 EGG08710.1 - 1.5e-14 53.7 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Nop25 PF09805.4 EGG08713.1 - 1.4e-16 60.7 16.9 1.4e-16 60.7 11.7 2.7 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Late_protein_L1 PF00500.13 EGG08713.1 - 0.04 12.4 0.1 0.056 11.9 0.0 1.2 1 0 0 1 1 1 0 L1 (late) protein R3H PF01424.17 EGG08714.1 - 9.7e-12 44.4 0.1 2.4e-11 43.1 0.1 1.7 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EGG08714.1 - 4.2e-08 33.0 0.0 9.1e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGG08714.1 - 2.3e-06 27.1 0.0 1e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG08714.1 - 2.9e-05 23.8 0.0 6.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MBF1 PF08523.5 EGG08715.1 - 2.1e-17 62.8 0.6 2.1e-17 62.8 0.4 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EGG08715.1 - 3.7e-11 42.6 0.1 7.4e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EGG08715.1 - 1.9e-07 31.0 0.0 2.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EGG08715.1 - 2.8e-05 24.2 0.0 0.0001 22.4 0.0 1.8 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.1 EGG08715.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain zf-C3HC4_3 PF13920.1 EGG08716.1 - 1.1 9.0 14.4 0.41 10.3 1.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CIAPIN1 PF05093.8 EGG08718.1 - 2.2e-29 101.4 5.0 2.3e-29 101.4 2.6 1.6 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF4041 PF13250.1 EGG08720.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) Sec63 PF02889.11 EGG08721.1 - 6e-39 134.1 0.6 9.1e-39 133.5 0.4 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EGG08721.1 - 3.9e-21 75.2 0.0 1.3e-20 73.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG08721.1 - 2.7e-09 36.7 0.0 9.3e-09 35.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG08721.1 - 4.5e-07 29.8 0.0 1.5e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Isy1 PF06246.7 EGG08721.1 - 0.0032 16.9 0.2 0.0088 15.4 0.1 1.8 1 1 0 1 1 1 1 Isy1-like splicing family Fork_head PF00250.13 EGG08722.1 - 4.8e-31 106.6 0.0 5.1e-31 106.5 0.0 1.0 1 0 0 1 1 1 1 Fork head domain XAP5 PF04921.9 EGG08723.1 - 2.8 7.4 11.0 3.3 7.2 7.6 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF3807 PF12720.2 EGG08723.1 - 7.3 6.7 9.3 8.2 6.5 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SprA-related PF12118.3 EGG08723.1 - 7.9 5.7 15.8 8.4 5.6 11.0 1.0 1 0 0 1 1 1 0 SprA-related family Polysacc_deac_1 PF01522.16 EGG08725.1 - 2.8e-28 98.0 0.0 3.5e-27 94.4 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGG08725.1 - 8.5e-05 21.6 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 RAP PF08373.5 EGG08725.1 - 0.019 14.7 0.0 4 7.2 0.0 2.7 2 0 0 2 2 2 0 RAP domain Head_binding PF09008.5 EGG08725.1 - 0.098 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Head binding Peroxidase_2 PF01328.12 EGG08726.1 - 3.4e-09 35.8 0.9 4.5e-08 32.1 0.6 2.1 1 1 0 1 1 1 1 Peroxidase, family 2 RVP PF00077.15 EGG08728.1 - 0.13 12.2 0.1 7 6.6 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease IFT43 PF15305.1 EGG08730.1 - 0.56 10.2 6.4 0.93 9.5 4.4 1.3 1 0 0 1 1 1 0 Intraflagellar transport protein 43 CRA PF06589.6 EGG08736.1 - 0.11 11.8 0.3 0.21 10.9 0.2 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DND1_DSRM PF14709.1 EGG08742.1 - 0.087 13.1 0.1 12 6.2 0.0 2.6 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 zf-CCHC_4 PF14392.1 EGG08748.1 - 0.052 13.2 3.8 0.086 12.5 2.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Mago-bind PF09282.5 EGG08749.1 - 0.016 14.7 0.3 6.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Mago binding NIF PF03031.13 EGG08750.1 - 5.6e-22 78.0 0.0 1.8e-21 76.4 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EGG08750.1 - 2.2e-05 24.2 0.5 0.0001 22.0 0.2 2.2 2 1 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EGG08750.1 - 0.0019 18.3 0.0 0.0047 17.0 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Nucleo_P87 PF07267.6 EGG08750.1 - 3.4 6.2 4.5 6.4 5.3 3.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Bromodomain PF00439.20 EGG08753.1 - 2.5e-25 88.2 0.2 6.4e-25 86.8 0.1 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EGG08753.1 - 3.1e-10 40.0 0.4 6.8e-10 38.9 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGG08753.1 - 6e-07 29.4 0.1 1e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GNAT_acetyltr_2 PF13718.1 EGG08753.1 - 0.075 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 RNase_H_2 PF13482.1 EGG08754.1 - 0.058 13.2 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 RNase_H superfamily SNF2_N PF00176.18 EGG08757.1 - 8.7e-27 93.6 0.3 8.7e-27 93.6 0.2 1.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.24 EGG08757.1 - 0.012 15.1 0.1 0.027 13.9 0.0 1.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG08758.1 - 0.00016 21.4 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC_3 PF13917.1 EGG08759.1 - 0.00033 20.3 0.6 0.00053 19.6 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGG08759.1 - 0.19 11.3 0.9 0.35 10.5 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Peptidase_C48 PF02902.14 EGG08760.1 - 0.00024 20.7 0.4 0.00037 20.1 0.0 1.5 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Inositol_P PF00459.20 EGG08762.1 - 1.6e-20 73.5 0.0 3e-19 69.3 0.0 2.2 1 1 0 1 1 1 1 Inositol monophosphatase family La PF05383.12 EGG08763.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 La domain Peptidase_C48 PF02902.14 EGG08764.1 - 2.3e-12 47.0 0.7 3e-12 46.6 0.5 1.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1675 PF07897.6 EGG08768.1 - 4.1 7.2 20.9 3.6 7.3 6.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) DUF3222 PF11519.3 EGG08769.1 - 0.0057 16.5 0.4 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3222) DUF1299 PF06975.6 EGG08770.1 - 1.8 8.4 4.4 0.39 10.6 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) BEN PF10523.4 EGG08773.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 BEN domain PA_decarbox PF05870.6 EGG08775.1 - 0.056 12.9 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) MMR_HSR1 PF01926.18 EGG08778.1 - 1.5e-16 60.3 0.0 6.5e-15 55.1 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGG08778.1 - 8.7e-06 25.1 0.0 5.5e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EGG08778.1 - 0.00014 21.0 0.0 0.00025 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Sporozoite_P67 PF05642.6 EGG08778.1 - 0.00041 18.3 3.0 0.00061 17.8 2.1 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Dynamin_N PF00350.18 EGG08778.1 - 0.028 14.2 0.0 0.094 12.5 0.0 1.9 1 0 0 1 1 1 0 Dynamin family AIG1 PF04548.11 EGG08778.1 - 0.042 12.9 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 EGG08778.1 - 0.052 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ArgK PF03308.11 EGG08778.1 - 0.18 10.5 0.0 0.4 9.4 0.0 1.5 1 0 0 1 1 1 0 ArgK protein SDA1 PF05285.7 EGG08778.1 - 0.77 8.9 12.4 2.3 7.4 7.2 2.1 2 0 0 2 2 2 0 SDA1 WD40 PF00400.27 EGG08781.1 - 8.7e-10 38.1 4.0 0.0096 15.7 0.0 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat Pkinase PF00069.20 EGG08782.1 - 8.7e-69 231.5 0.0 1.5e-68 230.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG08782.1 - 5e-47 160.1 0.0 7.9e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG08782.1 - 2.3e-05 23.4 0.0 0.00021 20.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Abhydrolase_6 PF12697.2 EGG08783.1 - 1.5e-17 64.2 0.0 2.1e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG08783.1 - 9e-14 51.5 0.1 5.2e-10 39.2 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG08783.1 - 2e-10 40.6 0.0 2.5e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGG08783.1 - 1.6e-08 34.2 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase PAF-AH_p_II PF03403.8 EGG08783.1 - 0.099 10.9 0.1 0.48 8.6 0.0 2.0 2 1 1 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II DUF702 PF05142.7 EGG08784.1 - 0.49 10.5 2.6 2.3 8.3 1.8 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) LTV PF04180.9 EGG08785.1 - 9.7e-47 160.4 17.6 6.9e-35 121.3 0.9 3.6 1 1 2 4 4 4 2 Low temperature viability protein LRR_4 PF12799.2 EGG08786.1 - 0.73 9.5 8.7 31 4.3 6.1 2.8 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) Voltage_CLC PF00654.15 EGG08787.1 - 8.5e-89 298.0 28.9 8.5e-89 298.0 20.1 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EGG08787.1 - 7.5e-08 32.0 0.1 3.6e-06 26.6 0.0 2.5 2 0 0 2 2 2 1 CBS domain Kelch_4 PF13418.1 EGG08788.1 - 8.2e-38 127.9 17.6 8.9e-09 34.9 0.0 6.9 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EGG08788.1 - 7.8e-36 121.4 9.3 2.3e-08 33.9 0.1 7.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EGG08788.1 - 5.8e-33 112.3 6.2 1.1e-06 28.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EGG08788.1 - 7.9e-30 101.7 9.7 6.8e-08 32.3 0.2 6.8 4 2 2 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EGG08788.1 - 1.3e-27 95.0 5.7 1.5e-08 34.0 0.2 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EGG08788.1 - 4e-23 80.2 14.1 3.8e-05 23.2 0.1 7.1 7 0 0 7 7 7 5 Kelch motif GCM PF03615.10 EGG08789.1 - 7.8e-05 22.3 1.4 0.00016 21.2 0.4 1.9 2 0 0 2 2 2 1 GCM motif protein DUF1936 PF09151.5 EGG08789.1 - 0.14 11.7 0.3 0.46 10.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) G5 PF07501.7 EGG08789.1 - 0.14 12.1 3.5 0.35 10.8 2.5 1.6 1 0 0 1 1 1 0 G5 domain Musclin PF11037.3 EGG08789.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle DUF1777 PF08648.7 EGG08791.1 - 2.1 8.0 25.1 5.2 6.7 17.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) FAP PF07174.6 EGG08793.1 - 0.66 9.2 13.4 0.18 11.0 4.6 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) eIF3_subunit PF08597.5 EGG08794.1 - 0.0039 16.7 5.4 0.0044 16.6 3.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit LRR_4 PF12799.2 EGG08795.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Taeniidae_ag PF05596.6 EGG08795.1 - 0.094 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Taeniidae antigen 2TM PF13239.1 EGG08806.1 - 0.079 13.0 0.1 0.097 12.7 0.1 1.2 1 0 0 1 1 1 0 2TM domain DUF3704 PF12488.3 EGG08806.1 - 0.17 11.5 0.8 0.57 9.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3704) TPR_19 PF14559.1 EGG08807.1 - 2.8e-06 27.5 0.0 0.08 13.2 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.26 EGG08807.1 - 4.1e-05 23.2 0.0 0.00017 21.2 0.0 2.1 1 0 0 1 1 1 1 DnaJ domain Apc3 PF12895.2 EGG08807.1 - 0.0029 17.7 0.6 7.7 6.7 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGG08807.1 - 0.0092 16.5 0.4 9.2 7.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGG08807.1 - 0.047 13.6 0.4 0.79 9.7 0.0 2.9 2 2 0 2 2 2 0 Tetratricopeptide repeat TRP PF06011.7 EGG08810.1 - 2.1e-45 155.1 23.3 6.2e-45 153.5 16.1 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Pkinase PF00069.20 EGG08813.1 - 4.1e-70 235.8 0.0 5.4e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG08813.1 - 2.1e-33 115.5 0.0 6.8e-32 110.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG08813.1 - 0.00021 20.3 0.9 0.17 10.7 0.2 2.6 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EGG08813.1 - 0.00078 18.8 0.8 0.0012 18.2 0.6 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGG08813.1 - 0.018 14.7 0.1 0.21 11.3 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EGG08813.1 - 0.087 11.5 0.2 0.18 10.5 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Patched PF02460.13 EGG08814.1 - 4.6e-63 213.3 7.1 1e-35 122.9 0.4 3.1 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.3 EGG08814.1 - 1.6e-42 144.5 12.1 6.7e-24 84.0 0.0 3.4 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 EGG08814.1 - 0.12 9.7 10.9 0.2 8.9 7.6 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Hamartin PF04388.7 EGG08816.1 - 5e-09 35.4 5.2 5e-09 35.4 3.6 4.1 3 1 1 4 4 4 1 Hamartin protein tRNA-synt_1c PF00749.16 EGG08817.1 - 1.3e-93 313.1 0.0 1.6e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain eIF-5_eIF-2B PF01873.12 EGG08818.1 - 4e-42 142.8 0.0 6.7e-42 142.0 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EGG08818.1 - 4.6e-25 87.3 0.1 4.6e-25 87.3 0.1 2.5 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DUF2387 PF09526.5 EGG08818.1 - 0.058 13.3 0.8 0.27 11.1 0.6 2.2 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Presenilin PF01080.12 EGG08821.1 - 1.1 8.0 3.3 1.3 7.7 2.3 1.0 1 0 0 1 1 1 0 Presenilin NST1 PF13945.1 EGG08821.1 - 2.1 8.3 7.9 2.8 7.9 5.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator PC-Esterase PF13839.1 EGG08822.1 - 1.1e-06 28.7 0.4 7.6e-05 22.6 0.3 2.5 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p MitMem_reg PF13012.1 EGG08823.1 - 5.4e-31 107.0 0.3 2e-30 105.2 0.2 1.9 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EGG08823.1 - 1.5e-22 79.4 0.0 2.5e-10 40.1 0.0 2.5 1 1 1 2 2 2 2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pex2_Pex12 PF04757.9 EGG08824.1 - 1.3e-26 93.4 14.4 2e-26 92.8 10.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EGG08824.1 - 6.9 6.7 10.5 11 6.1 4.3 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SUI1 PF01253.17 EGG08825.1 - 2.8e-11 43.0 0.2 8.4e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 PUA PF01472.15 EGG08825.1 - 0.00061 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 PUA domain Ig_2 PF13895.1 EGG08825.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Tannase PF07519.6 EGG08828.1 - 3.3e-82 276.7 0.0 2.2e-79 267.3 0.0 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase Tannase PF07519.6 EGG08831.1 - 4.2e-93 312.6 0.0 5.5e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 EGG08831.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Kelch_4 PF13418.1 EGG08833.1 - 6.2e-16 57.8 11.4 0.00059 19.5 0.1 5.2 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EGG08833.1 - 2e-12 46.9 13.8 0.021 14.9 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EGG08833.1 - 5.7e-09 35.7 7.7 0.012 15.5 0.1 4.9 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EGG08833.1 - 0.00095 18.6 9.1 2.3 7.8 0.1 6.3 7 0 0 7 7 7 2 Kelch motif Kelch_6 PF13964.1 EGG08833.1 - 0.0011 19.0 13.3 1.6 9.0 0.0 5.5 6 0 0 6 6 6 3 Kelch motif DUF3040 PF11239.3 EGG08833.1 - 0.26 11.3 0.2 4.6 7.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Pkinase PF00069.20 EGG08834.1 - 4.1e-28 98.2 0.0 4.6e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG08834.1 - 2.6e-21 75.8 0.0 2.9e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGG08834.1 - 0.014 14.4 0.9 0.17 10.9 0.0 2.0 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGG08834.1 - 0.014 15.0 0.1 0.026 14.2 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EGG08834.1 - 0.019 13.9 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 EGG08835.1 - 4.5e-13 48.9 0.0 4.9e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG08835.1 - 5.4e-09 35.5 0.0 5.4e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase JmjC PF02373.17 EGG08836.1 - 7.4e-13 48.7 0.6 2.2e-12 47.1 0.1 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EGG08836.1 - 0.00027 20.5 2.8 0.095 12.1 0.0 3.3 2 1 1 3 3 3 2 Cupin-like domain C1_1 PF00130.17 EGG08836.1 - 0.016 14.9 2.2 0.016 14.9 1.5 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PBP1_TM PF14812.1 EGG08836.1 - 0.074 13.3 5.8 2.1 8.7 1.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cyclin_N PF00134.18 EGG08838.1 - 2.7e-13 49.6 0.0 5e-10 39.0 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGG08838.1 - 0.051 13.4 4.1 0.42 10.5 0.0 2.8 3 0 0 3 3 3 0 Cyclin, C-terminal domain UBN2 PF14223.1 EGG08839.1 - 0.001 18.8 0.1 0.0062 16.3 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type MFS_1 PF07690.11 EGG08840.1 - 2.1e-38 131.9 35.7 2.1e-38 131.9 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGG08840.1 - 1.1e-05 23.9 1.3 1.1e-05 23.9 0.9 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2592 PF10766.4 EGG08840.1 - 0.1 11.9 3.1 0.23 10.8 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2592) OATP PF03137.15 EGG08840.1 - 0.33 8.9 10.9 0.47 8.4 0.8 3.2 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Pox_A21 PF05323.7 EGG08841.1 - 0.0023 18.3 1.8 0.42 11.0 0.0 2.2 2 0 0 2 2 2 2 Poxvirus A21 Protein OPT PF03169.10 EGG08842.1 - 3.6e-185 617.0 46.5 4.1e-185 616.8 32.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TMEMspv1-c74-12 PF11044.3 EGG08842.1 - 0.83 9.2 0.0 0.83 9.2 0.0 3.8 4 0 0 4 4 4 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein TPR_2 PF07719.12 EGG08843.1 - 7.8e-09 34.7 8.6 0.6 10.1 0.1 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGG08843.1 - 7e-08 32.2 0.8 4.9 7.1 0.0 5.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGG08843.1 - 2.8e-07 30.0 2.8 1.9 8.1 0.2 6.1 5 1 1 6 6 6 3 TPR repeat Suf PF05843.9 EGG08843.1 - 9.4e-06 25.5 17.4 0.062 13.0 2.6 5.2 4 1 0 4 4 4 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EGG08843.1 - 1.4e-05 25.3 1.2 21 6.1 0.0 7.3 6 2 2 8 8 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGG08843.1 - 1.4e-05 25.5 3.2 0.091 13.4 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EGG08843.1 - 3.1e-05 23.7 13.5 0.69 9.7 0.0 6.4 6 1 0 6 6 6 3 Mad3/BUB1 homology region 1 TPR_19 PF14559.1 EGG08843.1 - 3.2e-05 24.1 0.8 2.1 8.7 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG08843.1 - 0.0028 17.3 4.9 39 4.3 0.0 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGG08843.1 - 0.43 10.2 3.6 13 5.6 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGG08843.1 - 1.7 9.2 6.6 36 5.1 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGG08843.1 - 4.7 7.6 12.9 2.1 8.7 0.0 6.1 8 0 0 8 8 6 0 Tetratricopeptide repeat FAM176 PF14851.1 EGG08844.1 - 0.044 13.4 0.7 0.07 12.8 0.5 1.2 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 EGG08844.1 - 0.15 11.0 0.7 0.19 10.7 0.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 EGG08844.1 - 0.55 8.6 9.5 0.74 8.2 6.6 1.1 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 EGG08844.1 - 0.76 10.0 5.1 1.2 9.4 3.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF1510 PF07423.6 EGG08844.1 - 0.78 9.0 6.3 1.2 8.5 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nucleoplasmin PF03066.10 EGG08844.1 - 1.8 8.0 5.6 2.7 7.4 3.9 1.1 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EGG08844.1 - 2.5 5.9 6.3 3.2 5.5 4.4 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L18e PF00828.14 EGG08845.1 - 9.2e-31 106.8 0.3 1.2e-30 106.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 PI-PLC-X PF00388.14 EGG08846.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PROCN PF08083.6 EGG08849.1 - 8.6e-219 725.9 9.9 1.4e-218 725.3 6.9 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EGG08849.1 - 2.1e-125 416.6 0.8 3.6e-125 415.8 0.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EGG08849.1 - 9.8e-93 307.7 1.5 2.2e-92 306.6 1.0 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EGG08849.1 - 3.8e-80 266.8 2.6 3.8e-80 266.8 1.8 2.2 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EGG08849.1 - 2.8e-68 227.7 0.1 5.5e-68 226.7 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EGG08849.1 - 1.2e-43 146.9 0.5 3.1e-43 145.5 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EGG08849.1 - 4.3e-32 110.4 0.0 1.2e-31 108.9 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 EGG08849.1 - 0.023 14.4 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Amino_oxidase PF01593.19 EGG08851.1 - 1.2e-11 44.4 0.0 5.7e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGG08851.1 - 3.4e-11 42.9 0.1 9.3e-11 41.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGG08851.1 - 8.6e-06 24.8 0.0 1.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGG08851.1 - 0.0022 17.1 0.0 0.0047 16.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EGG08851.1 - 0.029 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGG08851.1 - 0.05 14.0 1.6 0.055 13.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGG08851.1 - 0.054 12.1 0.0 0.077 11.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EGG08851.1 - 0.081 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Histone PF00125.19 EGG08852.1 - 4.1e-14 52.4 0.1 5e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGG08852.1 - 3.8e-05 23.7 0.0 5e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EGG08852.1 - 0.00011 22.0 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EGG08852.1 - 0.0013 18.7 0.1 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGG08852.1 - 0.047 12.9 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CPSase_L_chain PF00289.17 EGG08853.1 - 1.7e-08 34.5 0.0 3.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EGG08853.1 - 4.1e-06 26.5 0.4 2.3e-05 24.1 0.2 2.2 1 1 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EGG08853.1 - 0.00069 19.3 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain WD40 PF00400.27 EGG08855.1 - 2.1e-06 27.4 9.9 0.03 14.2 0.0 4.8 5 1 0 5 5 5 3 WD domain, G-beta repeat ACT_6 PF13740.1 EGG08855.1 - 0.16 11.7 1.0 0.22 11.2 0.1 1.7 2 0 0 2 2 2 0 ACT domain PTH2 PF01981.11 EGG08857.1 - 5.4e-43 145.3 0.1 7.2e-43 144.9 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Glucan_synthase PF02364.10 EGG08858.1 - 0 1370.8 0.0 0 1370.3 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EGG08858.1 - 8.2e-39 132.1 0.1 2.1e-38 130.8 0.0 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Hid1 PF12722.2 EGG08859.1 - 0.053 11.2 1.0 0.067 10.8 0.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDRGK PF09756.4 EGG08859.1 - 0.35 10.2 23.5 0.49 9.7 16.3 1.1 1 0 0 1 1 1 0 DDRGK domain MAP7 PF05672.6 EGG08859.1 - 1.1 8.5 31.7 1.6 8.0 21.9 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DNA_pol_viral_N PF00242.12 EGG08859.1 - 1.6 7.6 7.1 2.5 7.0 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Ycf1 PF05758.7 EGG08859.1 - 2.3 5.8 7.6 3 5.4 5.2 1.1 1 0 0 1 1 1 0 Ycf1 Hom_end_hint PF05203.11 EGG08859.1 - 3.1 7.4 5.9 4.5 6.9 4.1 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint CAF-1_p150 PF11600.3 EGG08859.1 - 3.7 6.8 32.5 7.7 5.8 22.5 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spore_coat_CotO PF14153.1 EGG08859.1 - 6.2 6.2 16.6 10 5.5 11.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO TIP49 PF06068.8 EGG08862.1 - 9e-179 594.3 0.6 1.1e-178 594.0 0.4 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EGG08862.1 - 7.2e-08 32.7 0.1 7.2e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGG08862.1 - 1.6e-06 27.3 0.2 0.00092 18.3 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EGG08862.1 - 9.7e-06 24.6 0.2 1.7e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EGG08862.1 - 4.4e-05 23.6 0.1 0.088 12.9 0.0 2.8 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EGG08862.1 - 8.3e-05 21.8 1.0 0.0032 16.6 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EGG08862.1 - 0.00089 19.2 0.0 0.0053 16.7 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EGG08862.1 - 0.0076 15.3 0.1 0.016 14.2 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EGG08862.1 - 0.0076 16.1 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGG08862.1 - 0.02 14.3 0.1 0.049 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGG08862.1 - 0.023 14.4 0.2 7.1 6.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Sipho_tail PF05709.6 EGG08862.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Phage tail protein Pex19 PF04614.7 EGG08864.1 - 3e-54 184.2 11.9 5.1e-54 183.5 7.9 1.6 1 1 1 2 2 2 1 Pex19 protein family FliE PF02049.13 EGG08864.1 - 1.5 8.9 4.8 2.4 8.2 2.1 2.3 1 1 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Mito_carr PF00153.22 EGG08865.1 - 2.5e-43 145.6 10.9 1.8e-18 66.0 0.1 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein P22_Tail-4 PF11650.3 EGG08866.1 - 0.13 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 P22 tail accessory factor DUF1617 PF07761.7 EGG08867.1 - 0.069 13.2 0.4 0.14 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) SUR7 PF06687.7 EGG08868.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.5 1 1 0 1 1 1 1 SUR7/PalI family DUF3974 PF13120.1 EGG08868.1 - 0.018 14.8 0.3 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) DUF1218 PF06749.7 EGG08868.1 - 4.6 7.7 8.4 0.69 10.4 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) MARVEL PF01284.18 EGG08868.1 - 5.7 6.7 19.8 25 4.6 13.7 1.9 1 1 0 1 1 1 0 Membrane-associating domain UQ_con PF00179.21 EGG08869.1 - 1.7e-46 157.1 0.0 2.2e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGG08869.1 - 2.3e-05 24.1 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGG08869.1 - 0.0034 17.0 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EGG08869.1 - 0.0037 17.1 0.3 0.01 15.7 0.2 1.9 1 1 0 1 1 1 1 RWD domain Ribosomal_L2_C PF03947.13 EGG08870.1 - 3.8e-40 136.7 1.0 3.8e-40 136.7 0.7 2.5 2 1 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGG08870.1 - 1.5e-27 95.3 0.5 4.5e-27 93.8 0.2 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain MFS_1 PF07690.11 EGG08871.1 - 1e-30 106.6 24.4 1e-30 106.6 16.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily EAP30 PF04157.11 EGG08872.1 - 2.3e-45 154.4 0.0 2.7e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family YcbB PF08664.5 EGG08872.1 - 0.052 13.3 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 YcbB domain Pex2_Pex12 PF04757.9 EGG08873.1 - 2.4e-27 95.8 6.5 3.7e-27 95.2 4.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 EGG08873.1 - 7.9e-06 25.4 0.9 1.4e-05 24.6 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGG08873.1 - 6.3e-05 22.7 3.0 0.00013 21.7 2.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGG08873.1 - 0.00019 21.3 2.8 0.00034 20.5 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGG08873.1 - 0.00041 20.1 2.6 0.0012 18.7 1.9 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGG08873.1 - 0.0042 16.7 1.5 0.0083 15.8 1.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGG08873.1 - 0.0095 15.6 0.3 0.024 14.3 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger RDD PF06271.7 EGG08873.1 - 0.012 15.5 0.1 0.032 14.1 0.0 1.7 2 0 0 2 2 2 0 RDD family zf-C3HC4_3 PF13920.1 EGG08873.1 - 0.024 14.2 1.0 0.039 13.6 0.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3219 PF11514.3 EGG08874.1 - 0.048 13.5 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3219) Malic_M PF03949.10 EGG08875.1 - 8.7e-84 281.0 0.0 1.1e-83 280.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EGG08875.1 - 2.5e-64 216.2 0.0 3.5e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain AAA_9 PF12781.2 EGG08875.1 - 0.15 10.8 0.0 0.7 8.6 0.0 1.8 2 0 0 2 2 2 0 ATP-binding dynein motor region D5 Aminotran_3 PF00202.16 EGG08876.1 - 1.4e-99 333.2 0.0 1.8e-99 332.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGG08876.1 - 6.7e-05 21.9 0.0 8.9e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGG08876.1 - 0.0089 15.2 0.0 0.021 14.0 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Glyco_hydro_71 PF03659.9 EGG08877.1 - 2.1e-53 181.1 1.4 5.8e-36 123.7 0.6 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 71 SEF14_adhesin PF06443.6 EGG08877.1 - 0.048 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 SEF14-like adhesin Bromodomain PF00439.20 EGG08878.1 - 1.7e-20 72.7 0.0 3.4e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DUF1569 PF07606.6 EGG08878.1 - 0.064 13.1 0.1 0.2 11.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) Hydantoinase_B PF02538.9 EGG08879.1 - 7e-190 631.7 0.0 1.2e-189 630.9 0.0 1.3 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Methyltransf_12 PF08242.7 EGG08882.1 - 5.5e-13 49.2 0.0 1.2e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG08882.1 - 1.7e-12 47.3 0.0 2.3e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG08882.1 - 2.1e-08 34.7 0.0 3.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG08882.1 - 4.6e-08 33.3 0.0 2.4e-07 31.0 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG08882.1 - 2.3e-07 30.5 0.0 1.3e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG08882.1 - 4.7e-07 30.2 0.0 1.2e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG08882.1 - 0.00011 21.6 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGG08882.1 - 0.0023 17.9 0.0 0.0048 16.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EGG08882.1 - 0.0043 16.0 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_24 PF13578.1 EGG08882.1 - 0.026 15.3 0.0 0.049 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EGG08882.1 - 0.05 12.6 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase RAB3GAP2_C PF14656.1 EGG08884.1 - 0.54 8.3 2.8 0.74 7.8 2.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Herpes_U5 PF05999.6 EGG08885.1 - 0.01 14.4 0.1 0.014 14.0 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus U5-like family Utp12 PF04003.7 EGG08885.1 - 0.67 9.8 4.2 1.3 8.9 2.9 1.5 1 1 0 1 1 1 0 Dip2/Utp12 Family PLRV_ORF5 PF01690.12 EGG08885.1 - 1.3 8.0 9.8 1.5 7.8 6.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PH_10 PF15411.1 EGG08888.1 - 1.3e-29 102.7 0.2 4.1e-29 101.1 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain zf-RING_2 PF13639.1 EGG08888.1 - 7.8e-08 32.0 1.8 1.7e-07 30.9 1.2 1.6 1 0 0 1 1 1 1 Ring finger domain VWA_3 PF13768.1 EGG08888.1 - 8.1e-05 22.3 0.0 0.2 11.3 0.0 2.7 2 0 0 2 2 2 2 von Willebrand factor type A domain zf-RING_5 PF14634.1 EGG08888.1 - 0.00043 19.9 1.1 0.0013 18.4 0.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGG08888.1 - 0.00069 19.5 2.3 0.0019 18.1 1.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EGG08888.1 - 0.14 12.1 0.2 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.2 EGG08888.1 - 0.19 11.8 0.7 0.54 10.3 0.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGG08888.1 - 0.75 9.5 1.7 1.8 8.2 1.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Histone PF00125.19 EGG08889.1 - 5.4e-31 106.5 0.4 8.6e-31 105.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGG08889.1 - 7.9e-05 22.7 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGG08889.1 - 0.004 17.1 0.1 0.004 17.1 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PRAI PF00697.17 EGG08889.1 - 0.053 13.0 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Bromo_TP PF07524.8 EGG08889.1 - 0.056 13.1 0.1 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 EGG08889.1 - 0.13 12.0 0.2 0.23 11.2 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit bZIP_2 PF07716.10 EGG08890.1 - 3.5e-06 26.7 9.6 1.5e-05 24.6 4.8 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EGG08890.1 - 0.0002 21.2 7.5 0.0002 21.2 5.2 2.3 2 0 0 2 2 2 1 bZIP transcription factor TSC22 PF01166.13 EGG08890.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family GHMP_kinases_N PF00288.21 EGG08893.1 - 8.1e-09 35.4 4.1 1.4e-08 34.6 0.5 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF2721 PF11026.3 EGG08893.1 - 0.069 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Macoilin PF09726.4 EGG08894.1 - 0.00027 19.3 0.3 0.00027 19.3 0.2 1.0 1 0 0 1 1 1 1 Transmembrane protein CobT PF06213.7 EGG08894.1 - 0.034 13.3 3.9 0.039 13.0 2.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 EGG08894.1 - 0.24 10.7 2.6 0.49 9.7 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) NOA36 PF06524.7 EGG08894.1 - 0.27 10.4 5.8 0.37 9.9 4.0 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.6 EGG08894.1 - 2.3 7.6 6.8 3.2 7.2 4.7 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.7 EGG08894.1 - 2.7 5.7 8.1 3.7 5.3 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2670 PF10875.3 EGG08895.1 - 0.039 13.9 0.2 0.086 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) SGS PF05002.10 EGG08896.1 - 0.075 12.7 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 SGS domain HTH_Tnp_Tc5 PF03221.11 EGG08897.1 - 1.5e-14 53.5 0.0 2.6e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain WRC PF08879.5 EGG08897.1 - 0.041 13.5 0.8 0.1 12.2 0.5 1.7 1 0 0 1 1 1 0 WRC RNA_pol_L_2 PF13656.1 EGG08899.1 - 3.3e-25 87.3 0.1 4.4e-25 86.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EGG08899.1 - 1.3e-11 43.4 0.0 1.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CX PF01705.14 EGG08899.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 CX module Cytochrom_B561 PF03188.11 EGG08900.1 - 8.3e-14 51.5 7.0 8.3e-14 51.5 4.9 1.9 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 NADH-u_ox-rdase PF10785.4 EGG08900.1 - 0.06 13.5 1.2 2.2 8.5 0.1 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit SdpI PF13630.1 EGG08900.1 - 8.5 6.1 15.3 1.2 8.9 0.3 3.2 3 0 0 3 3 3 0 SdpI/YhfL protein family SPT16 PF08644.6 EGG08901.1 - 6.1e-50 169.0 0.5 6.1e-50 169.0 0.3 2.5 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EGG08901.1 - 3.4e-44 150.2 0.3 1.2e-43 148.4 0.0 2.2 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 EGG08901.1 - 1e-22 79.9 0.1 2.2e-21 75.6 0.0 2.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 EGG08901.1 - 6.9e-21 74.7 0.0 2.9e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 Metallopeptidase family M24 Adaptin_N PF01602.15 EGG08905.1 - 4.1e-138 460.9 10.5 4.9e-138 460.7 7.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGG08905.1 - 2.7e-22 79.4 4.9 6.7e-22 78.1 0.1 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGG08905.1 - 4.4e-15 55.7 7.8 2.4e-09 37.3 0.1 4.7 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EGG08905.1 - 1.2e-09 37.3 0.5 0.0012 18.7 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EGG08905.1 - 0.00037 20.8 2.3 0.25 11.8 0.0 4.4 3 1 1 4 4 4 1 HEAT-like repeat DUF1548 PF07579.6 EGG08905.1 - 0.00063 19.8 1.1 0.012 15.7 0.0 3.2 4 0 0 4 4 4 1 Domain of Unknown Function (DUF1548) CLASP_N PF12348.3 EGG08905.1 - 0.0027 17.0 2.4 2.4 7.4 0.0 3.7 3 1 0 4 4 4 2 CLASP N terminal Arm PF00514.18 EGG08905.1 - 0.0048 16.6 0.0 1.1 9.1 0.0 3.2 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat FA PF08736.6 EGG08905.1 - 0.45 10.3 2.4 8.2 6.3 0.0 3.0 3 0 0 3 3 3 0 FERM adjacent (FA) zf-AN1 PF01428.11 EGG08906.1 - 1.4e-08 34.4 7.4 1.4e-08 34.4 5.1 1.7 1 1 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.16 EGG08906.1 - 0.056 13.3 4.4 0.11 12.4 3.1 1.6 1 0 0 1 1 1 0 IBR domain Sulfate_transp PF00916.15 EGG08907.1 - 3.2e-53 180.5 8.2 9.2e-53 179.0 5.1 2.0 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGG08907.1 - 1.7e-24 85.2 2.3 1.7e-24 85.2 1.6 2.4 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGG08907.1 - 2.9e-17 62.1 0.1 5.3e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain Diphthamide_syn PF01866.12 EGG08908.1 - 5.5e-86 288.5 0.0 1.3e-53 182.2 0.0 3.6 1 1 0 2 2 2 2 Putative diphthamide synthesis protein Ras PF00071.17 EGG08909.1 - 9.1e-54 181.2 0.1 1.1e-53 180.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG08909.1 - 1.5e-18 67.3 0.0 3.2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG08909.1 - 5.7e-18 64.7 0.0 6.8e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGG08909.1 - 6.8e-10 38.6 0.0 1.5e-07 31.0 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGG08909.1 - 6.3e-08 32.0 0.1 7.9e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGG08909.1 - 1.8e-07 31.1 0.0 3.5e-07 30.1 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGG08909.1 - 0.0016 17.6 0.0 0.0035 16.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EGG08909.1 - 0.0031 17.3 1.1 0.012 15.4 0.7 2.2 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.13 EGG08909.1 - 0.017 14.4 0.1 0.073 12.3 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 EGG08909.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EGG08909.1 - 0.064 12.8 0.1 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGG08909.1 - 0.068 13.3 0.0 0.38 10.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 EGG08909.1 - 0.074 12.2 0.5 0.27 10.3 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGG08909.1 - 0.079 12.3 0.0 0.77 9.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EGG08909.1 - 0.092 12.4 0.2 0.37 10.5 0.0 1.9 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DEAD PF00270.24 EGG08910.1 - 1.6e-40 138.3 0.0 2.1e-39 134.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG08910.1 - 1.9e-23 82.1 0.1 4.3e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGG08910.1 - 0.0002 20.2 0.0 0.00032 19.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGG08910.1 - 0.019 14.7 0.0 0.076 12.8 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pkinase PF00069.20 EGG08911.1 - 7.6e-58 195.6 0.0 8.7e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG08911.1 - 1.1e-25 90.1 0.0 1.3e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG08911.1 - 0.002 17.1 0.0 0.0062 15.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGG08911.1 - 0.088 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PC-Esterase PF13839.1 EGG08913.1 - 3.9e-05 23.5 0.0 0.00063 19.6 0.0 2.2 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Cas1_AcylT PF07779.7 EGG08914.1 - 1.7e-150 501.7 29.1 4.3e-150 500.4 20.2 1.5 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EGG08914.1 - 2.8e-25 89.6 0.1 4.8e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p MFS_1 PF07690.11 EGG08916.1 - 2.3e-28 98.9 47.6 2.3e-28 98.9 33.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Cytochrom_C_2 PF01322.15 EGG08917.1 - 0.15 12.5 1.4 6.6 7.2 0.2 2.9 3 0 0 3 3 3 0 Cytochrome C' DDE_3 PF13358.1 EGG08918.1 - 6.4e-09 35.7 0.0 1.5e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.1 EGG08918.1 - 0.028 15.2 0.0 0.15 12.8 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain AAA_14 PF13173.1 EGG08918.1 - 0.048 13.5 0.2 0.75 9.7 0.1 2.1 1 1 1 2 2 2 0 AAA domain PLA2_B PF01735.13 EGG08921.1 - 9.4e-102 340.6 0.0 1.2e-101 340.3 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.13 EGG08922.1 - 1.5e-101 340.0 0.0 1.9e-101 339.6 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF4218 PF13960.1 EGG08927.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) PAH PF02671.16 EGG08928.1 - 0.022 14.3 0.2 0.022 14.3 0.1 2.6 3 0 0 3 3 3 0 Paired amphipathic helix repeat DUF1664 PF07889.7 EGG08928.1 - 2.3 8.0 11.2 1.9 8.3 0.3 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) 5_3_exonuc_N PF02739.11 EGG08929.1 - 0.11 11.8 0.1 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain Sad1_UNC PF07738.8 EGG08930.1 - 2.6e-27 95.2 0.0 5.2e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CfAFP PF05264.6 EGG08930.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) HSF_DNA-bind PF00447.12 EGG08932.1 - 6.6e-32 109.7 1.5 8.8e-32 109.3 1.0 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding DUF72 PF01904.13 EGG08932.1 - 0.0083 15.9 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF72 VRR_NUC PF08774.6 EGG08932.1 - 0.072 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 VRR-NUC domain PPP4R2 PF09184.6 EGG08933.1 - 0.03 13.8 18.4 0.034 13.6 12.8 1.0 1 0 0 1 1 1 0 PPP4R2 Hid1 PF12722.2 EGG08933.1 - 0.21 9.1 9.4 0.25 8.9 6.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GEMIN8 PF15348.1 EGG08933.1 - 0.39 10.7 13.0 0.47 10.4 9.0 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Nha1_C PF08619.5 EGG08933.1 - 0.63 9.2 16.8 0.75 9.0 11.7 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus NOA36 PF06524.7 EGG08933.1 - 1.3 8.2 12.3 1.4 8.1 8.5 1.0 1 0 0 1 1 1 0 NOA36 protein Spore_coat_CotO PF14153.1 EGG08933.1 - 2.3 7.6 12.3 2.4 7.5 8.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF2722 PF10846.3 EGG08933.1 - 2.3 7.1 12.8 2.7 6.9 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Daxx PF03344.10 EGG08933.1 - 7.2 4.9 20.7 7.6 4.8 14.3 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 EGG08933.1 - 7.4 5.8 15.6 7.7 5.8 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) YL1 PF05764.8 EGG08934.1 - 0.2 11.2 11.9 0.25 10.9 8.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Mucin PF01456.12 EGG08934.1 - 0.24 11.1 6.9 0.3 10.8 4.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SR-25 PF10500.4 EGG08934.1 - 0.3 10.5 22.9 0.41 10.0 15.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TATR PF03430.8 EGG08934.1 - 1.6 7.3 10.2 1.8 7.1 7.0 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Pex14_N PF04695.8 EGG08934.1 - 2.3 8.2 11.1 6.8 6.7 7.7 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2146 PF10220.4 EGG08934.1 - 3.5 5.4 8.2 3.6 5.4 5.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Apt1 PF10351.4 EGG08934.1 - 9.1 5.0 14.2 11 4.7 9.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain FA_desaturase PF00487.19 EGG08938.1 - 0.00034 20.1 20.5 0.0007 19.1 14.2 1.6 1 1 0 1 1 1 1 Fatty acid desaturase UPF0220 PF05255.6 EGG08944.1 - 6.4e-52 175.1 0.0 7.4e-52 174.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DJ-1_PfpI_N PF13587.1 EGG08944.1 - 0.0083 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF1751 PF08551.5 EGG08944.1 - 0.068 13.4 0.4 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Glyco_hydro_15 PF00723.16 EGG08945.1 - 3.2e-69 233.6 0.0 3.8e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Fibroin_P25 PF07294.6 EGG08945.1 - 0.098 12.1 0.3 0.17 11.3 0.2 1.3 1 0 0 1 1 1 0 Fibroin P25 Acyltransferase PF01553.16 EGG08946.1 - 6.6e-22 77.3 0.0 1.2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF1311 PF07007.7 EGG08947.1 - 0.0026 17.8 0.1 0.0026 17.8 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1311) Med15 PF09606.5 EGG08947.1 - 2.3 6.3 17.7 2.4 6.2 12.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_L37ae PF01780.14 EGG08949.1 - 2.4e-40 136.2 10.5 2.7e-40 136.1 7.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EGG08949.1 - 0.00024 20.8 2.1 0.00036 20.2 1.4 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 EGG08949.1 - 0.0024 17.5 3.2 0.06 13.1 0.1 2.3 1 1 1 2 2 2 2 BED zinc finger DUF1364 PF07102.7 EGG08949.1 - 0.05 13.4 1.5 0.064 13.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) A2L_zn_ribbon PF08792.5 EGG08949.1 - 0.07 12.6 2.4 1 8.8 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain GFA PF04828.9 EGG08949.1 - 0.076 12.9 1.0 3.9 7.4 0.1 2.1 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Rsm1 PF08600.5 EGG08949.1 - 0.1 12.4 0.4 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Rsm1-like Elf1 PF05129.8 EGG08949.1 - 0.11 12.2 2.6 0.2 11.3 1.8 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.5 EGG08949.1 - 0.11 12.4 1.2 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 EGG08949.1 - 0.57 10.1 3.4 17 5.5 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGG08949.1 - 0.63 10.4 6.1 3.3 8.1 0.7 2.3 1 1 1 2 2 2 0 Zinc-finger double domain SKN1 PF03935.10 EGG08950.1 - 7.7e-184 611.5 2.9 8.5e-184 611.3 2.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 EGG08950.1 - 2.1e-07 30.4 0.2 4.7e-06 26.0 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 ELO PF01151.13 EGG08951.1 - 4.6e-59 199.7 20.3 5.5e-59 199.4 14.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PRO8NT PF08082.6 EGG08954.1 - 1.4e-26 92.9 4.0 2.5e-17 62.9 0.2 2.7 2 1 1 3 3 3 2 PRO8NT (NUC069), PrP8 N-terminal domain DUF4095 PF13338.1 EGG08955.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) IL3 PF02059.10 EGG08955.1 - 0.085 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Interleukin-3 MCPVI PF02993.9 EGG08957.1 - 0.3 11.2 5.5 1.1 9.3 4.0 1.7 2 0 0 2 2 2 0 Minor capsid protein VI DUF4291 PF14124.1 EGG08959.1 - 0.052 13.1 0.4 0.13 11.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) OmpH PF03938.9 EGG08959.1 - 2.6 7.9 7.8 0.19 11.6 0.5 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF1253 PF06862.7 EGG08964.1 - 2.3e-127 425.0 0.5 3.1e-127 424.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Img2 PF05046.9 EGG08967.1 - 3.1e-12 46.5 0.0 5.4e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) RAI16-like PF10257.4 EGG08970.1 - 8e-47 159.8 0.0 2.1e-46 158.4 0.0 1.8 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein CorA PF01544.13 EGG08971.1 - 1.5e-07 30.7 3.2 2.6e-07 29.9 2.2 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein RNR_N PF08343.5 EGG08971.1 - 0.096 12.4 0.3 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal Exo_endo_phos_2 PF14529.1 EGG08976.1 - 9.2e-12 44.6 0.1 1.1e-11 44.4 0.1 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EGG08977.1 - 2.4e-06 27.9 0.0 4.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNase H Peptidase_A25 PF03418.9 EGG08977.1 - 0.12 11.1 0.1 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Germination protease DUF559 PF04480.7 EGG08982.1 - 0.082 12.5 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF559) Helitron_like_N PF14214.1 EGG08987.1 - 0.04 13.6 0.1 0.078 12.6 0.0 1.5 1 1 0 1 1 1 0 Helitron helicase-like domain at N-terminus NatB_MDM20 PF09797.4 EGG08987.1 - 0.078 11.6 0.1 0.1 11.2 0.1 1.1 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit ALG3 PF05208.8 EGG08988.1 - 6.1e-30 104.6 25.8 2.8e-13 49.8 4.2 3.0 1 1 2 3 3 3 3 ALG3 protein NST1 PF13945.1 EGG08991.1 - 0.1 12.6 3.7 0.14 12.2 2.6 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator PTCB-BRCT PF12738.2 EGG08992.1 - 4.1e-06 26.5 0.0 2.6e-05 23.9 0.0 2.4 3 0 0 3 3 3 1 twin BRCT domain DUF3496 PF12001.3 EGG08995.1 - 0.033 14.4 0.1 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) NOA36 PF06524.7 EGG08995.1 - 0.051 12.8 2.4 0.071 12.3 1.6 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EGG08995.1 - 0.065 12.7 9.2 0.12 11.8 6.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin Tim54 PF11711.3 EGG08995.1 - 0.16 10.5 7.8 0.21 10.1 5.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CENP-B_dimeris PF09026.5 EGG08995.1 - 0.26 11.5 15.4 0.19 12.0 9.3 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EBV-NA3 PF05009.7 EGG08995.1 - 0.36 10.0 7.6 0.33 10.1 4.2 1.6 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) TLP-20 PF06088.6 EGG08995.1 - 0.6 9.7 6.4 1 9.0 4.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.9 EGG08995.1 - 0.68 7.8 7.9 0.75 7.7 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 EGG08995.1 - 2 7.9 18.1 0.34 10.4 9.2 1.8 1 1 1 2 2 2 0 YL1 nuclear protein DUF4611 PF15387.1 EGG08995.1 - 2.1 8.5 12.0 0.24 11.5 4.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AA_permease_2 PF13520.1 EGG08996.1 - 1.3e-61 208.4 42.3 1.6e-61 208.1 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGG08996.1 - 1.7e-25 89.3 39.0 2.4e-25 88.8 27.1 1.1 1 0 0 1 1 1 1 Amino acid permease BUD22 PF09073.5 EGG08997.1 - 8e-40 137.2 31.7 9.6e-30 104.0 17.5 3.4 1 1 1 2 2 2 2 BUD22 DUF4071 PF13281.1 EGG08997.1 - 0.044 12.6 0.1 0.075 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) P12 PF12669.2 EGG08998.1 - 0.12 12.5 9.0 0.28 11.4 5.1 2.0 2 0 0 2 2 2 0 Virus attachment protein p12 family Conotoxin PF02950.12 EGG08998.1 - 1.5 9.7 7.6 2.8 8.8 5.3 1.4 1 1 0 1 1 1 0 Conotoxin ICL PF00463.16 EGG09000.1 - 1.6e-173 577.7 0.0 2e-173 577.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EGG09000.1 - 6.5e-15 54.9 0.1 2.2e-13 49.9 0.0 2.3 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF979 PF06166.7 EGG09001.1 - 0.087 11.7 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF979) UCH PF00443.24 EGG09003.1 - 4e-27 94.9 2.1 4.1e-27 94.9 0.1 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGG09003.1 - 6.2e-10 39.0 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein SAP PF02037.22 EGG09003.1 - 1.1e-09 37.5 4.2 2.7e-09 36.3 2.9 1.7 1 0 0 1 1 1 1 SAP domain UCH_1 PF13423.1 EGG09003.1 - 2.8e-05 23.7 5.2 4e-05 23.1 0.0 3.1 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase HeH PF12949.2 EGG09003.1 - 0.076 12.5 1.4 0.26 10.8 0.9 1.9 1 1 0 1 1 1 0 HeH/LEM domain RNA_pol_Rpb2_6 PF00562.23 EGG09004.1 - 2.6e-128 428.0 0.1 4e-128 427.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGG09004.1 - 6.3e-66 221.1 0.0 9.3e-66 220.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGG09004.1 - 3.7e-49 166.7 0.1 1.8e-48 164.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EGG09004.1 - 5.1e-29 100.3 0.1 1.2e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EGG09004.1 - 5.2e-25 87.0 0.7 1.3e-24 85.8 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EGG09004.1 - 7.2e-24 83.5 0.6 1.5e-23 82.5 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EGG09004.1 - 9.3e-24 82.9 0.0 1.9e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 Varsurf_PPLC PF03490.8 EGG09004.1 - 0.034 13.8 0.1 0.25 11.0 0.0 2.3 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C HNH_3 PF13392.1 EGG09004.1 - 0.16 11.3 0.3 0.43 10.0 0.2 1.7 1 0 0 1 1 1 0 HNH endonuclease zf-UBP PF02148.14 EGG09005.1 - 0.021 14.9 5.8 0.051 13.6 4.0 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein YokU PF14122.1 EGG09005.1 - 0.18 11.5 1.5 0.43 10.3 0.2 2.0 2 0 0 2 2 2 0 YokU-like protein Transpos_assoc PF13963.1 EGG09005.1 - 0.53 10.3 3.0 0.32 10.9 0.3 1.9 2 0 0 2 2 2 0 Transposase-associated domain zf-C2HC PF01530.13 EGG09005.1 - 0.77 9.5 0.1 0.77 9.5 0.1 4.1 5 0 0 5 5 5 0 Zinc finger, C2HC type DUF3760 PF12586.3 EGG09007.1 - 0.11 12.3 1.0 20 5.1 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3760) DUF4372 PF14294.1 EGG09009.1 - 0.082 12.7 0.1 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) Nop14 PF04147.7 EGG09011.1 - 5.7e-37 127.1 4.4 1.3e-16 59.7 0.0 3.0 1 1 2 3 3 3 3 Nop14-like family FAD_binding_3 PF01494.14 EGG09012.1 - 1.6e-63 214.9 0.0 3.2e-62 210.6 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGG09012.1 - 1.9e-19 69.9 0.0 2.9e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 EGG09012.1 - 0.0023 17.9 0.0 0.01 15.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGG09012.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGG09012.1 - 0.0064 15.0 0.0 0.0093 14.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EGG09012.1 - 0.027 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EGG09012.1 - 0.028 13.5 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EGG09012.1 - 0.052 12.4 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein PQ-loop PF04193.9 EGG09013.1 - 3.5e-12 45.6 0.2 4.9e-12 45.2 0.2 1.2 1 0 0 1 1 1 1 PQ loop repeat eIF3_N PF09440.5 EGG09014.1 - 0.02 15.0 0.7 0.03 14.4 0.2 1.6 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain DUF1598 PF07643.6 EGG09014.1 - 0.12 12.4 0.1 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) Nup54 PF13874.1 EGG09014.1 - 1.5 8.4 5.8 1.1 8.8 1.5 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 JmjC PF02373.17 EGG09015.1 - 4.8e-10 39.6 0.0 5.3e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase DUF4510 PF14971.1 EGG09017.1 - 0.096 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Mating_C PF12737.2 EGG09018.1 - 0.22 10.3 1.1 0.29 9.9 0.7 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 U-box PF04564.10 EGG09019.1 - 1.2 9.1 5.7 26 4.8 0.0 4.2 4 0 0 4 4 4 0 U-box domain Snf7 PF03357.16 EGG09021.1 - 3.4e-18 65.6 7.6 4.2e-18 65.3 5.3 1.1 1 0 0 1 1 1 1 Snf7 YiiD_Cterm PF09500.5 EGG09021.1 - 0.019 14.5 0.1 0.025 14.1 0.1 1.2 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) FAM117 PF15388.1 EGG09021.1 - 0.11 11.6 1.2 0.12 11.5 0.9 1.1 1 0 0 1 1 1 0 Protein Family FAM117 tRNA-synt_2e PF02091.10 EGG09021.1 - 0.12 11.4 0.2 0.15 11.1 0.1 1.0 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit JmjC PF02373.17 EGG09025.1 - 2.3e-13 50.3 0.0 3.4e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EGG09025.1 - 0.00034 20.1 0.1 0.00052 19.5 0.0 1.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 EGG09025.1 - 0.087 12.3 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Cupin domain SinI PF08671.5 EGG09025.1 - 0.88 9.0 3.3 2.1 7.8 0.0 2.7 3 0 0 3 3 3 0 Anti-repressor SinI BolA PF01722.13 EGG09026.1 - 1.7e-15 56.7 0.1 2e-15 56.4 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein p450 PF00067.17 EGG09027.1 - 2.7e-52 177.8 0.0 3.7e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LRR_4 PF12799.2 EGG09029.1 - 3.9e-34 115.6 25.7 1.8e-07 30.6 0.4 8.8 6 2 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG09029.1 - 7.5e-25 86.4 25.6 2.1e-08 33.8 0.8 6.5 5 1 2 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 EGG09029.1 - 5.7e-09 34.7 25.4 0.53 10.5 0.1 11.4 11 2 1 12 12 12 3 Leucine Rich Repeat LRR_6 PF13516.1 EGG09029.1 - 1.2e-06 27.9 12.4 1.7 8.9 0.0 7.6 7 2 2 9 9 9 2 Leucine Rich repeat LRR_7 PF13504.1 EGG09029.1 - 0.002 18.0 26.7 4.4 7.9 0.3 10.9 13 0 0 13 13 13 2 Leucine rich repeat LRR_9 PF14580.1 EGG09029.1 - 0.0084 15.6 10.0 0.017 14.6 0.2 4.0 3 1 1 5 5 5 1 Leucine-rich repeat HTH_33 PF13592.1 EGG09031.1 - 8 6.0 9.5 1.2 8.6 2.2 2.6 2 0 0 2 2 2 0 Winged helix-turn helix Lin-8 PF03353.10 EGG09033.1 - 1.8 7.7 10.4 0.24 10.6 4.2 1.6 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist SHS2_FTSA PF02491.15 EGG09035.1 - 0.05 13.4 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA ALG3 PF05208.8 EGG09036.1 - 5.3e-122 407.6 19.6 6.8e-122 407.2 13.6 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.1 EGG09036.1 - 1.6e-05 24.0 15.4 1.6e-05 24.0 10.7 1.5 2 0 0 2 2 2 1 EpsG family Ribosomal_L18ae PF01775.12 EGG09038.1 - 2.7e-10 40.2 0.1 3.2e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Glyco_hydro_18 PF00704.23 EGG09040.1 - 2.4e-51 175.1 0.2 3.1e-51 174.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF702 PF05142.7 EGG09041.1 - 0.045 13.9 0.1 0.15 12.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF2670 PF10875.3 EGG09041.1 - 0.14 12.1 0.1 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) EcoEI_R_C PF08463.5 EGG09044.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 EcoEI R protein C-terminal Barttin PF15462.1 EGG09045.1 - 0.24 11.0 2.0 0.3 10.6 1.4 1.2 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) VIT1 PF01988.14 EGG09046.1 - 0.67 9.4 2.6 0.85 9.0 1.8 1.2 1 0 0 1 1 1 0 VIT family Neuromodulin_N PF10580.4 EGG09046.1 - 0.98 9.1 7.4 1.2 8.8 0.1 3.1 2 1 1 3 3 3 0 Gap junction protein N-terminal region CDC45 PF02724.9 EGG09046.1 - 1.5 6.7 16.7 3.2 5.6 11.5 1.5 1 0 0 1 1 1 0 CDC45-like protein DUF2606 PF10794.4 EGG09047.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) MRP-S31 PF15433.1 EGG09048.1 - 0.016 14.6 0.7 0.023 14.1 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 zf-Mss51 PF13824.1 EGG09048.1 - 2 8.3 3.7 0.94 9.3 0.9 1.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Herpes_LMP1 PF05297.6 EGG09049.1 - 3.7 6.3 8.1 4.7 6.0 5.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ECSIT PF06239.6 EGG09052.1 - 0.053 12.3 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway MCM PF00493.18 EGG09053.1 - 5.7e-128 426.3 0.2 8.4e-128 425.8 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGG09053.1 - 5.7e-23 81.6 0.1 1.6e-22 80.2 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGG09053.1 - 6e-08 32.1 0.4 1.4e-06 27.6 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGG09053.1 - 0.0024 17.4 0.0 0.0063 16.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGG09053.1 - 0.0072 15.8 0.0 0.02 14.3 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EGG09053.1 - 0.055 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LSM PF01423.17 EGG09054.1 - 1.4e-09 37.3 0.0 1.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain UPF0086 PF01868.11 EGG09054.1 - 0.12 12.0 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function UPF0086 Tmemb_14 PF03647.8 EGG09055.1 - 4.3e-22 78.3 9.9 4.9e-22 78.1 6.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Xpo1 PF08389.7 EGG09056.1 - 4.7e-15 55.7 0.6 1.6e-12 47.5 0.1 3.4 2 1 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EGG09056.1 - 0.00015 21.6 0.0 0.0033 17.3 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.17 EGG09056.1 - 0.002 18.0 0.0 0.012 15.5 0.0 2.5 1 0 0 1 1 1 1 HEAT repeat HMG_box PF00505.14 EGG09058.1 - 0.05 13.8 0.2 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box zf-CCHC_3 PF13917.1 EGG09059.1 - 0.035 13.8 1.4 0.035 13.8 1.0 2.7 4 0 0 4 4 4 0 Zinc knuckle Ribosomal_L37ae PF01780.14 EGG09061.1 - 7.2e-32 109.1 5.9 7.9e-32 108.9 4.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EGG09061.1 - 0.00016 21.3 2.1 0.00024 20.8 1.4 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 EGG09061.1 - 0.0015 18.2 3.2 0.041 13.6 0.1 2.1 1 1 1 2 2 2 2 BED zinc finger DUF1364 PF07102.7 EGG09061.1 - 0.031 14.1 1.6 0.036 13.9 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) A2L_zn_ribbon PF08792.5 EGG09061.1 - 0.041 13.3 2.4 0.75 9.3 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain GFA PF04828.9 EGG09061.1 - 0.052 13.5 1.1 2.6 8.0 0.1 2.1 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme GCC2_GCC3 PF07699.8 EGG09061.1 - 0.06 12.9 0.2 0.08 12.5 0.1 1.2 1 0 0 1 1 1 0 GCC2 and GCC3 Rsm1 PF08600.5 EGG09061.1 - 0.064 13.1 0.4 0.078 12.8 0.3 1.2 1 0 0 1 1 1 0 Rsm1-like Elf1 PF05129.8 EGG09061.1 - 0.094 12.4 2.7 0.17 11.6 1.8 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.5 EGG09061.1 - 0.15 12.0 2.4 0.9 9.5 0.2 2.4 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 EGG09061.1 - 0.23 11.4 2.8 11 6.0 0.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 EGG09061.1 - 0.23 11.0 1.4 2.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.1 EGG09061.1 - 0.34 11.3 5.9 2.3 8.6 0.7 2.2 1 1 1 2 2 2 0 Zinc-finger double domain C1_2 PF03107.11 EGG09061.1 - 0.56 10.3 3.1 2.5 8.3 0.3 2.2 2 0 0 2 2 2 0 C1 domain Ribosomal_L44 PF00935.14 EGG09061.1 - 1.6 8.8 5.9 32 4.6 4.2 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 WTF PF03303.8 EGG09063.1 - 0.28 10.5 3.2 0.45 9.8 2.2 1.3 1 0 0 1 1 1 0 WTF protein Methyltransf_16 PF10294.4 EGG09066.1 - 3.8e-20 72.0 0.0 4.4e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Sld5 PF05916.6 EGG09067.1 - 0.00086 19.5 0.1 0.0017 18.6 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein Alpha-L-AF_C PF06964.7 EGG09072.1 - 1.9e-18 66.8 0.1 1.3e-17 64.1 0.0 2.2 2 1 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 EGG09072.1 - 0.0029 17.5 0.2 0.0057 16.6 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain CBM_2 PF00553.14 EGG09072.1 - 0.025 14.6 0.6 0.025 14.6 0.4 2.6 3 0 0 3 3 3 0 Cellulose binding domain PI3K_rbd PF00794.13 EGG09072.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain Pkinase PF00069.20 EGG09073.1 - 4.3e-73 245.6 0.1 8.1e-73 244.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG09073.1 - 2.2e-36 125.2 0.6 4.5e-36 124.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG09073.1 - 0.00071 18.6 1.8 0.00077 18.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGG09073.1 - 0.0089 15.7 3.5 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGG09073.1 - 0.096 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 G-alpha PF00503.15 EGG09074.1 - 2.1e-112 375.6 0.0 2.6e-112 375.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGG09074.1 - 2e-15 56.4 0.9 2.3e-09 36.7 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGG09074.1 - 0.00084 18.5 0.7 0.4 9.7 0.1 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EGG09074.1 - 0.00094 19.6 0.1 0.57 10.6 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA PF00004.24 EGG09075.1 - 1.3e-53 180.7 0.0 2.1e-39 134.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 EGG09075.1 - 7.3e-10 38.3 0.4 1.5e-07 30.9 0.1 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EGG09075.1 - 1.1e-08 35.3 0.1 0.0022 18.1 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EGG09075.1 - 1.7e-08 34.5 0.0 9.3e-06 25.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EGG09075.1 - 4.5e-08 33.0 0.0 0.00076 19.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EGG09075.1 - 1.3e-07 30.7 0.4 0.0025 16.5 0.0 2.9 2 1 1 3 3 3 2 TIP49 C-terminus AAA_16 PF13191.1 EGG09075.1 - 2.3e-07 30.9 0.1 0.027 14.4 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EGG09075.1 - 2.6e-07 31.4 0.0 0.036 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGG09075.1 - 4.9e-07 29.5 0.0 0.00016 21.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGG09075.1 - 9.1e-07 28.1 0.1 0.023 13.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGG09075.1 - 1.2e-06 28.1 0.2 0.043 13.5 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 EGG09075.1 - 4e-06 26.7 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGG09075.1 - 6.8e-06 26.4 0.0 0.08 13.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain CDC48_N PF02359.13 EGG09075.1 - 1.5e-05 24.8 0.0 6e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain Mg_chelatase PF01078.16 EGG09075.1 - 1.5e-05 24.2 0.2 0.0038 16.4 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EGG09075.1 - 2e-05 24.2 1.8 0.058 12.9 0.1 3.7 3 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EGG09075.1 - 5.1e-05 23.0 0.0 15 5.2 0.0 4.1 2 2 2 4 4 4 0 Archaeal ATPase AAA_25 PF13481.1 EGG09075.1 - 6e-05 22.5 0.2 0.45 9.8 0.0 3.3 2 1 1 3 3 3 2 AAA domain IstB_IS21 PF01695.12 EGG09075.1 - 7.2e-05 22.2 1.1 0.062 12.7 0.0 2.9 4 0 0 4 4 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EGG09075.1 - 0.00014 22.0 0.0 0.095 12.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EGG09075.1 - 0.00018 21.4 0.0 0.3 11.0 0.0 2.7 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EGG09075.1 - 0.00022 20.3 0.0 0.3 10.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin Parvo_NS1 PF01057.12 EGG09075.1 - 0.00027 19.8 0.0 0.38 9.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EGG09075.1 - 0.00034 20.1 0.0 1.2 8.5 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EGG09075.1 - 0.00045 20.5 0.1 0.078 13.2 0.0 3.1 3 0 0 3 3 3 1 ABC transporter NACHT PF05729.7 EGG09075.1 - 0.00064 19.4 0.1 1.8 8.2 0.0 3.3 3 1 0 3 3 2 2 NACHT domain AAA_11 PF13086.1 EGG09075.1 - 0.00082 19.0 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 EGG09075.1 - 0.0011 18.1 0.4 0.025 13.6 0.1 2.5 2 1 0 2 2 2 1 KaiC KTI12 PF08433.5 EGG09075.1 - 0.0014 17.8 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_3 PF07726.6 EGG09075.1 - 0.0018 17.8 0.0 0.25 10.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EGG09075.1 - 0.0038 16.8 0.0 0.84 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EGG09075.1 - 0.018 14.2 0.0 2.1 7.5 0.0 2.6 3 0 0 3 3 2 0 PhoH-like protein CPT PF07931.7 EGG09075.1 - 0.02 14.5 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein IPT PF01745.11 EGG09075.1 - 0.022 13.9 0.1 0.62 9.1 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase T2SE PF00437.15 EGG09075.1 - 0.023 13.6 0.0 6.8 5.4 0.0 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 EGG09075.1 - 0.036 13.6 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EGG09075.1 - 0.043 12.6 0.0 4.2 6.1 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.4 EGG09075.1 - 0.07 12.0 0.0 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 EGG09075.1 - 0.11 12.5 0.0 10 6.1 0.0 3.2 4 0 0 4 4 3 0 Sigma-54 interaction domain adh_short PF00106.20 EGG09078.1 - 1.3e-15 57.7 0.1 1.9e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG09078.1 - 6e-07 29.4 0.0 9.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG09078.1 - 0.00019 21.1 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGG09078.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGG09078.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Galanin PF01296.13 EGG09079.1 - 0.054 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Galanin C2 PF00168.25 EGG09082.1 - 1.2e-09 37.8 0.0 3.7e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 C2 domain Mmp37 PF09139.6 EGG09083.1 - 2.9e-109 365.0 0.0 5.4e-109 364.1 0.0 1.4 2 0 0 2 2 2 1 Mitochondrial matrix Mmp37 Sec61_beta PF03911.11 EGG09084.1 - 2.8e-13 49.4 0.0 3.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Sec61beta family DUF2474 PF10617.4 EGG09084.1 - 0.054 13.1 0.6 0.11 12.1 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2474) RabGAP-TBC PF00566.13 EGG09085.1 - 6.7e-43 146.6 0.6 6.7e-43 146.6 0.4 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 EGG09085.1 - 6.4e-06 26.2 1.4 6.4e-06 26.2 1.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EGG09085.1 - 1.5e-05 24.4 3.2 0.0056 16.4 0.1 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EGG09085.1 - 0.00031 19.8 1.1 0.049 12.9 0.0 3.3 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 EGG09085.1 - 0.019 14.5 0.3 0.093 12.3 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain pair Pkinase PF00069.20 EGG09090.1 - 1.3e-14 54.0 0.0 1.4e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG09090.1 - 1.3e-05 24.4 0.0 1.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG09090.1 - 0.021 13.8 0.0 0.025 13.5 0.0 1.2 1 1 0 1 1 1 0 Kinase-like SPO22 PF08631.5 EGG09090.1 - 0.11 11.5 0.1 0.75 8.8 0.0 1.9 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like DUF1934 PF09148.5 EGG09091.1 - 0.0071 16.0 0.2 0.0097 15.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1934) Asn_synthase PF00733.16 EGG09092.1 - 1.2e-67 228.1 0.0 3.7e-67 226.4 0.0 1.8 2 1 0 2 2 2 1 Asparagine synthase GATase_7 PF13537.1 EGG09092.1 - 1.3e-35 121.8 0.0 2.8e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGG09092.1 - 1.5e-28 99.3 0.0 4.9e-28 97.7 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EGG09092.1 - 1.2e-06 27.9 0.0 2.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EGG09092.1 - 1.4e-06 27.2 0.0 0.23 10.1 0.0 3.1 1 1 2 3 3 3 3 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EGG09092.1 - 0.00085 18.2 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 NAD synthase QueC PF06508.8 EGG09092.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC MutL PF13941.1 EGG09094.1 - 0.0027 16.0 0.1 0.0045 15.3 0.0 1.2 1 0 0 1 1 1 1 MutL protein DUF3095 PF11294.3 EGG09094.1 - 0.034 13.1 1.3 0.059 12.3 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) DUF2036 PF09724.4 EGG09095.1 - 6.1e-47 160.3 7.9 7.8e-47 159.9 5.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) TrmE_N PF10396.4 EGG09095.1 - 0.14 12.1 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus Asp PF00026.18 EGG09096.1 - 5.7e-22 78.3 0.1 7.7e-21 74.6 0.0 2.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG09096.1 - 9.8e-08 32.1 0.0 1.2e-05 25.2 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Zn_clus PF00172.13 EGG09097.1 - 0.0029 17.4 4.9 0.0029 17.4 3.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FCH PF00611.18 EGG09097.1 - 0.052 13.7 0.6 0.2 11.8 0.4 2.1 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain GTP_CH_N PF12471.3 EGG09099.1 - 3.9e-86 287.6 0.0 5.6e-86 287.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EGG09099.1 - 3.8e-14 52.2 0.0 5.7e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II 4HBT_3 PF13622.1 EGG09102.1 - 2.9e-24 86.1 1.8 3.5e-24 85.9 1.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Metallophos_2 PF12850.2 EGG09107.1 - 6.2e-06 26.1 0.1 1.5e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGG09107.1 - 5e-05 22.7 0.0 0.00018 20.9 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Apc13p PF05839.6 EGG09108.1 - 0.03 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Apc13p protein DUF982 PF06169.7 EGG09108.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF982) Glyco_trans_2_3 PF13632.1 EGG09109.1 - 3.5e-26 92.1 5.3 3.5e-26 92.1 3.7 4.4 5 0 0 5 5 5 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGG09109.1 - 1.9e-20 73.6 0.0 3.7e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Acyl_transf_3 PF01757.17 EGG09109.1 - 2.9e-17 62.5 38.6 2.9e-17 62.5 26.7 3.1 3 0 0 3 3 3 1 Acyltransferase family PX PF00787.19 EGG09110.1 - 1.8e-21 76.0 0.3 4.8e-21 74.6 0.2 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EGG09110.1 - 1.7e-08 34.0 2.8 0.0014 17.9 0.1 2.3 2 0 0 2 2 2 2 Vps5 C terminal like Abhydrolase_6 PF12697.2 EGG09111.1 - 6.7e-32 111.2 0.0 8.7e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG09111.1 - 9.2e-21 74.4 0.0 4.3e-20 72.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG09111.1 - 5.7e-16 58.5 0.0 9.6e-16 57.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGG09111.1 - 2.9e-11 43.3 0.2 7.8e-11 41.9 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EGG09111.1 - 3.4e-08 34.0 0.0 4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 EGG09111.1 - 1.8e-05 24.1 0.0 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.3 EGG09111.1 - 3.2e-05 23.7 0.0 6.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF915 PF06028.6 EGG09111.1 - 0.00014 21.0 1.2 0.048 12.7 0.1 3.0 2 1 1 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.2 EGG09111.1 - 0.00035 19.5 0.0 0.00052 18.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EGG09111.1 - 0.00055 18.8 0.0 0.00081 18.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Ndr PF03096.9 EGG09111.1 - 0.0014 17.1 0.0 0.0021 16.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Lipase_2 PF01674.13 EGG09111.1 - 0.0071 15.6 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 2) Lipase_3 PF01764.20 EGG09111.1 - 0.0087 15.6 0.0 0.027 14.1 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) DUF3444 PF11926.3 EGG09111.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) DUF2305 PF10230.4 EGG09111.1 - 0.013 14.9 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) PAF-AH_p_II PF03403.8 EGG09111.1 - 0.017 13.4 0.5 0.27 9.4 0.0 2.4 2 1 1 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II LCAT PF02450.10 EGG09111.1 - 0.023 13.6 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 EGG09111.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.8 EGG09111.1 - 0.035 13.6 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EGG09111.1 - 0.043 13.4 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Esterase PF00756.15 EGG09111.1 - 0.055 12.8 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF2048 PF09752.4 EGG09111.1 - 0.073 11.9 0.2 0.47 9.2 0.1 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DLH PF01738.13 EGG09111.1 - 0.17 11.1 0.0 1.9 7.6 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family Asp PF00026.18 EGG09113.1 - 1.5e-62 211.6 0.3 1.8e-62 211.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG09113.1 - 0.00014 21.8 0.0 0.00036 20.5 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGG09113.1 - 0.0042 17.5 0.2 2.3 8.7 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease Asp PF00026.18 EGG09114.1 - 7.5e-61 206.1 0.0 8.7e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG09114.1 - 9e-06 25.7 0.0 3.4e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGG09114.1 - 9.4e-05 22.8 0.6 0.078 13.4 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease CNH PF00780.17 EGG09115.1 - 4.7e-57 193.4 0.0 7.3e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EGG09115.1 - 2.4e-26 92.7 0.4 3.7e-26 92.0 0.3 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EGG09115.1 - 3e-17 62.8 0.0 6.3e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.16 EGG09115.1 - 0.0021 17.7 0.0 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TPT PF03151.11 EGG09116.1 - 9.2e-11 41.6 7.0 9.2e-11 41.6 4.8 3.6 1 1 1 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 EGG09116.1 - 1.9e-10 40.1 17.6 4.1e-10 39.0 12.2 1.5 1 1 0 1 1 1 1 UAA transporter family BTG PF07742.7 EGG09118.1 - 0.029 13.8 0.0 0.072 12.5 0.0 1.6 1 0 0 1 1 1 0 BTG family zf-MYND PF01753.13 EGG09121.1 - 2.8e-08 33.4 10.4 5.9e-08 32.4 7.2 1.5 1 0 0 1 1 1 1 MYND finger HlyD PF00529.15 EGG09122.1 - 1.6 7.9 10.0 2.2 7.5 6.9 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Peptidase_S46 PF10459.4 EGG09122.1 - 6.3 5.0 16.2 7.3 4.8 11.2 1.1 1 0 0 1 1 1 0 Peptidase S46 Peptidase_M16 PF00675.15 EGG09124.1 - 9.7e-07 28.6 0.0 9.7e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF3435 PF11917.3 EGG09125.1 - 1.3e-06 27.4 0.0 2.4e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) ECIST_Cterm PF14784.1 EGG09126.1 - 0.0017 18.3 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 C-terminal domain of the ECSIT protein DUF3289 PF11692.3 EGG09126.1 - 0.042 13.1 0.1 0.045 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) YTH PF04146.10 EGG09126.1 - 0.063 12.8 1.6 0.069 12.7 1.1 1.1 1 0 0 1 1 1 0 YT521-B-like domain 7TM_GPCR_Srx PF10328.4 EGG09126.1 - 0.083 11.9 1.0 0.092 11.8 0.7 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx SHR3_chaperone PF08229.6 EGG09127.1 - 8.8e-23 80.2 4.7 6.2e-11 41.6 1.2 2.1 2 0 0 2 2 2 2 ER membrane protein SH3 DUF3353 PF11833.3 EGG09127.1 - 0.048 13.1 2.7 2.8 7.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) Rot1 PF10681.4 EGG09128.1 - 3.8e-65 219.2 0.6 4.6e-65 218.9 0.4 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal SF3b10 PF07189.6 EGG09129.1 - 2.5e-33 113.7 0.0 3.1e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) AIP3 PF03915.8 EGG09131.1 - 7.3e-104 348.0 1.0 7.3e-104 348.0 0.7 1.7 2 0 0 2 2 2 1 Actin interacting protein 3 AAA_13 PF13166.1 EGG09131.1 - 0.00014 20.4 5.6 0.00017 20.2 2.8 2.0 2 0 0 2 2 2 1 AAA domain Lectin_N PF03954.9 EGG09131.1 - 0.0051 16.2 4.8 0.0051 16.2 3.3 3.4 2 1 1 3 3 3 1 Hepatic lectin, N-terminal domain WEMBL PF05701.6 EGG09131.1 - 0.021 13.3 10.9 0.023 13.1 0.8 3.2 2 1 1 3 3 3 0 Weak chloroplast movement under blue light Spc24 PF08286.6 EGG09131.1 - 0.071 12.8 12.4 0.79 9.4 0.0 4.4 3 1 1 4 4 4 0 Spc24 subunit of Ndc80 TBPIP PF07106.8 EGG09131.1 - 0.074 12.5 10.6 0.67 9.4 3.7 3.5 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 EGG09131.1 - 0.12 12.1 15.4 7.8 6.3 0.1 3.8 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 EGG09131.1 - 0.12 12.4 13.6 0.053 13.6 1.9 3.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DivIVA PF05103.8 EGG09131.1 - 0.15 12.0 8.2 1.6 8.8 0.9 3.9 2 1 0 3 3 3 0 DivIVA protein NPV_P10 PF05531.7 EGG09131.1 - 0.17 12.1 13.1 3.7 7.8 0.0 4.1 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EGG09131.1 - 0.19 11.5 11.8 0.61 9.8 3.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Prefoldin PF02996.12 EGG09131.1 - 0.25 10.9 6.9 5.5 6.6 0.0 4.2 4 1 1 5 5 5 0 Prefoldin subunit DUF904 PF06005.7 EGG09131.1 - 0.36 11.1 6.6 0.66 10.3 3.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF4559 PF15112.1 EGG09131.1 - 0.48 9.5 7.4 0.53 9.4 3.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) FlaC_arch PF05377.6 EGG09131.1 - 0.61 10.0 10.1 12 5.9 0.4 5.0 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.6 EGG09131.1 - 1 9.8 17.9 2.6 8.5 0.1 4.9 4 1 1 5 5 4 0 Syntaxin 6, N-terminal RasGAP_C PF03836.10 EGG09131.1 - 1.1 8.9 6.8 2.4 7.8 0.1 3.3 2 1 1 3 3 3 0 RasGAP C-terminus Allexi_40kDa PF05549.6 EGG09131.1 - 1.7 7.8 8.2 2.5 7.3 1.1 3.0 1 1 1 3 3 3 0 Allexivirus 40kDa protein DUF1515 PF07439.6 EGG09131.1 - 1.9 8.3 6.2 3 7.6 1.1 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1515) zf-CCHC_3 PF13917.1 EGG09133.1 - 0.026 14.2 21.3 0.21 11.3 4.6 2.5 1 1 1 2 2 2 0 Zinc knuckle Yae1_N PF09811.4 EGG09134.1 - 0.021 14.3 0.4 0.046 13.2 0.3 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Zn_ribbon_2 PF12674.2 EGG09135.1 - 0.17 12.2 0.6 0.17 12.2 0.4 1.9 2 1 0 2 2 2 0 Putative zinc ribbon domain C1_2 PF03107.11 EGG09135.1 - 0.53 10.4 6.3 0.56 10.3 0.7 2.9 3 0 0 3 3 3 0 C1 domain PRP1_N PF06424.7 EGG09136.1 - 1.6e-45 154.6 2.3 1.9e-45 154.4 0.3 2.1 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EGG09136.1 - 2.2e-26 89.9 5.0 0.016 15.7 0.1 13.6 6 4 8 14 14 14 6 Tetratricopeptide repeat TPR_19 PF14559.1 EGG09136.1 - 1.2e-17 63.9 7.8 3.7e-06 27.1 0.1 8.8 7 3 3 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGG09136.1 - 9.3e-17 61.2 5.3 0.036 14.7 0.0 7.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGG09136.1 - 4.8e-08 32.3 1.2 24 5.1 0.0 9.9 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_15 PF13429.1 EGG09136.1 - 2.6e-07 30.0 5.8 0.026 13.6 0.0 6.0 4 2 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGG09136.1 - 7e-05 22.7 3.7 3.1 8.2 0.0 7.8 10 0 0 10 10 9 1 Tetratricopeptide repeat NARP1 PF12569.3 EGG09136.1 - 0.00011 21.1 4.3 0.038 12.7 0.0 4.5 2 1 3 5 5 5 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 EGG09136.1 - 0.00012 22.2 6.0 1.1e+02 3.6 0.0 9.0 11 0 0 11 11 11 0 Tetratricopeptide repeat Suf PF05843.9 EGG09136.1 - 0.00025 20.8 0.2 6 6.4 0.1 5.0 3 2 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EGG09136.1 - 0.00043 19.8 11.9 3.6 7.3 0.0 7.5 6 3 1 8 8 8 1 TPR repeat TPR_8 PF13181.1 EGG09136.1 - 0.0034 17.0 0.4 60 3.7 0.0 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 EGG09136.1 - 0.012 15.5 9.4 0.018 14.9 0.3 3.9 3 1 2 5 5 5 0 Tetratricopeptide repeat NUDIX PF00293.23 EGG09137.1 - 1.2e-07 31.4 0.1 1.4e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain F-actin_cap_A PF01267.12 EGG09139.1 - 4.7e-86 288.2 2.3 5.3e-86 288.0 1.6 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF2278 PF10042.4 EGG09139.1 - 0.039 13.6 0.0 0.068 12.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2278) FAR1 PF03101.10 EGG09140.1 - 6.4e-06 26.6 0.1 3e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.6 EGG09140.1 - 0.00069 19.7 0.2 0.00069 19.7 0.1 1.9 2 1 0 2 2 2 1 Transcription factor AFT MutS_IV PF05190.13 EGG09140.1 - 0.026 14.6 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV DUF3275 PF11679.3 EGG09141.1 - 0.071 12.7 2.6 0.26 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) DUF4218 PF13960.1 EGG09143.1 - 0.0042 16.5 0.0 0.007 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Tcp10_C PF07202.8 EGG09143.1 - 0.032 13.7 0.1 0.051 13.1 0.1 1.2 1 0 0 1 1 1 0 T-complex protein 10 C-terminus Sad1_UNC PF07738.8 EGG09144.1 - 6.1e-27 94.0 0.0 9.5e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DAGK_cat PF00781.19 EGG09146.1 - 2.4e-11 43.1 0.0 4.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Thr_synth_N PF14821.1 EGG09147.1 - 8.2e-28 96.2 0.0 1.2e-26 92.5 0.0 2.7 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 EGG09147.1 - 2.2e-16 59.9 0.0 4.6e-16 58.9 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TFIIS_M PF07500.9 EGG09148.1 - 2.1e-16 60.0 2.1 4.2e-16 59.0 1.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EGG09148.1 - 6.4e-06 26.6 0.0 1.8e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EGG09148.1 - 0.00064 19.3 11.4 0.29 10.8 7.9 2.5 1 1 0 1 1 1 1 PHD-finger UFC1 PF08694.6 EGG09150.1 - 0.018 14.5 1.3 0.031 13.7 0.6 1.6 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 zf-CCHC_3 PF13917.1 EGG09152.1 - 0.00019 21.0 0.2 0.00032 20.3 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGG09152.1 - 0.034 13.8 0.3 0.088 12.4 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle Sad1_UNC PF07738.8 EGG09154.1 - 9.8e-29 99.8 0.0 1.7e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal NPV_P10 PF05531.7 EGG09154.1 - 0.033 14.4 1.7 1.2 9.4 0.1 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DASH_Dad3 PF08656.5 EGG09154.1 - 0.98 9.1 3.1 0.87 9.3 1.1 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad3 RXT2_N PF08595.6 EGG09155.1 - 0.035 13.9 8.0 0.076 12.8 5.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Spore_coat_CotO PF14153.1 EGG09155.1 - 0.13 11.6 9.9 0.19 11.1 6.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Otopetrin PF03189.8 EGG09155.1 - 0.25 10.2 1.1 0.24 10.3 0.7 1.1 1 0 0 1 1 1 0 Otopetrin DUF1754 PF08555.5 EGG09155.1 - 0.32 11.6 11.6 0.59 10.7 8.1 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF4578 PF15147.1 EGG09155.1 - 0.41 11.0 7.5 1.1 9.5 5.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4578) DUF4544 PF15077.1 EGG09155.1 - 0.85 9.0 6.6 3.1 7.2 3.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4544) FAM60A PF15396.1 EGG09155.1 - 1.2 8.8 6.9 1.8 8.2 4.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Sec62 PF03839.11 EGG09155.1 - 2.8 7.2 4.8 4.4 6.6 3.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 SMN PF06003.7 EGG09155.1 - 5.4 6.0 7.5 8.1 5.4 5.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RNA_polI_A14 PF08203.6 EGG09156.1 - 0.014 15.6 1.1 1.4 9.1 0.1 2.5 1 1 1 2 2 2 0 Yeast RNA polymerase I subunit RPA14 DUF2365 PF10157.4 EGG09156.1 - 0.039 13.8 0.2 0.067 13.0 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) ApoLp-III PF07464.6 EGG09156.1 - 0.11 12.4 0.2 0.21 11.6 0.1 1.6 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Topoisom_bac PF01131.15 EGG09158.1 - 1.4e-96 323.7 0.0 1.7e-96 323.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EGG09158.1 - 4.6e-18 65.0 0.0 1.5e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 Toprim domain zf-CCHC PF00098.18 EGG09159.1 - 1.1e-14 53.5 17.1 9.8e-07 28.4 1.0 3.2 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.1 EGG09159.1 - 0.0007 19.2 15.9 0.0034 17.0 1.3 3.0 2 1 1 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.1 EGG09159.1 - 0.0012 18.3 0.1 0.0012 18.3 0.1 2.9 3 0 0 3 3 3 1 Zinc knuckle eIF3g PF12353.3 EGG09159.1 - 0.053 13.4 8.5 0.085 12.7 0.6 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Copper-fist PF00649.13 EGG09159.1 - 0.13 11.5 3.9 0.72 9.1 0.1 2.4 2 0 0 2 2 2 0 Copper fist DNA binding domain PHD PF00628.24 EGG09159.1 - 0.46 10.2 9.1 0.085 12.5 3.2 1.9 2 0 0 2 2 2 0 PHD-finger DUF3454 PF11936.3 EGG09159.1 - 0.47 10.6 3.7 0.76 10.0 2.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3454) Perm-CXXC PF15629.1 EGG09159.1 - 1.8 8.5 10.6 1.3 9.0 1.2 3.4 3 0 0 3 3 3 0 Permuted single zf-CXXC unit zf-CCHC_4 PF14392.1 EGG09159.1 - 1.9 8.2 12.7 1.7 8.3 0.5 2.8 3 0 0 3 3 3 0 Zinc knuckle IBR PF01485.16 EGG09159.1 - 3.7 7.5 15.6 4 7.3 1.1 3.0 2 1 1 3 3 3 0 IBR domain Thi4 PF01946.12 EGG09161.1 - 0.055 12.5 0.1 0.073 12.1 0.0 1.1 1 0 0 1 1 1 0 Thi4 family Gly-rich_Ago1 PF12764.2 EGG09162.1 - 0.078 13.6 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycine-rich region of argonaut HK PF02110.10 EGG09163.1 - 2.9e-08 33.2 2.1 9e-08 31.5 1.5 1.7 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family Semialdhyde_dh PF01118.19 EGG09166.1 - 0.11 12.7 0.0 0.32 11.3 0.0 1.7 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EGG09166.1 - 0.13 11.1 0.0 12 4.6 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein WD40 PF00400.27 EGG09167.1 - 2.1e-84 274.6 28.9 8e-13 47.7 0.5 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EGG09167.1 - 4.8e-09 34.8 7.0 0.0038 15.4 0.6 5.2 2 1 2 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EGG09167.1 - 1.3e-05 24.9 0.0 0.00081 19.1 0.0 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EGG09167.1 - 1.8e-05 23.6 0.2 0.82 8.3 0.0 3.3 2 1 1 3 3 3 3 Nup133 N terminal like Nbas_N PF15492.1 EGG09167.1 - 0.0096 15.0 0.1 1.9 7.5 0.0 3.1 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 EGG09167.1 - 0.023 14.1 1.2 0.093 12.1 0.2 2.3 3 0 0 3 3 3 0 PQQ-like domain NLE PF08154.7 EGG09167.1 - 0.026 14.5 0.1 0.049 13.6 0.1 1.4 1 0 0 1 1 1 0 NLE (NUC135) domain Spc24 PF08286.6 EGG09167.1 - 0.048 13.3 0.4 0.09 12.4 0.3 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Asp PF00026.18 EGG09168.1 - 3.6e-66 223.5 1.6 4.5e-66 223.2 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG09168.1 - 4.5e-06 26.7 1.8 3e-05 24.0 0.7 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Chorion_1 PF01723.11 EGG09169.1 - 0.0022 17.9 0.3 0.0031 17.4 0.2 1.4 1 1 0 1 1 1 1 Chorion protein Polysacc_deac_1 PF01522.16 EGG09172.1 - 3.7e-25 87.9 0.0 6.4e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Proteasome PF00227.21 EGG09174.1 - 4.4e-35 120.6 0.0 5.3e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit zf-H2C2_2 PF13465.1 EGG09177.1 - 5.9e-05 23.1 7.6 5.9e-05 23.1 5.3 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGG09177.1 - 8.4e-05 22.6 10.0 0.0092 16.2 1.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG09177.1 - 0.00011 22.2 11.1 0.012 15.9 1.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGG09177.1 - 0.063 13.1 1.0 0.19 11.6 0.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Ribosomal_L16 PF00252.13 EGG09178.1 - 1.3e-37 128.4 0.0 1.5e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Sdh_cyt PF01127.17 EGG09179.1 - 1.9e-21 76.1 0.3 3.1e-21 75.4 0.2 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sec23_trunk PF04811.10 EGG09179.1 - 0.037 13.4 0.0 0.096 12.0 0.0 1.8 1 1 0 1 1 1 0 Sec23/Sec24 trunk domain zf-H2C2_2 PF13465.1 EGG09180.1 - 2.5e-11 43.2 11.7 3.8e-06 26.9 0.3 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EGG09180.1 - 9.4e-10 38.2 14.8 0.005 17.1 0.0 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG09180.1 - 1.3e-09 37.6 11.4 0.0027 17.9 0.9 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGG09180.1 - 0.0066 16.5 2.3 0.028 14.5 0.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGG09180.1 - 0.18 11.7 14.2 1.2 9.1 0.3 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger CTP_transf_1 PF01148.15 EGG09181.1 - 5.2e-13 49.2 4.3 9.8e-12 45.0 1.4 1.9 1 1 1 2 2 2 2 Cytidylyltransferase family DUF4118 PF13493.1 EGG09181.1 - 3.5 7.8 6.5 0.79 9.9 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) PH_4 PF15404.1 EGG09183.1 - 2.1e-31 108.9 0.6 2.1e-31 108.9 0.4 2.5 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 EGG09183.1 - 5.6e-05 23.2 12.2 0.0026 17.9 0.4 4.1 3 1 0 3 3 3 2 PH domain RhoGEF PF00621.15 EGG09184.1 - 3.3e-19 69.4 6.1 3.3e-19 69.4 4.2 1.8 2 0 0 2 2 2 1 RhoGEF domain UPF0183 PF03676.9 EGG09185.1 - 4.3e-35 121.0 0.0 4.1e-34 117.8 0.0 2.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) Alpha_kinase PF02816.13 EGG09186.1 - 2e-08 34.1 0.5 8.7e-08 32.0 0.3 1.8 1 1 0 1 1 1 1 Alpha-kinase family Glucosamine_iso PF01182.15 EGG09189.1 - 7.1e-56 189.0 0.0 9.4e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF832 PF05734.6 EGG09189.1 - 0.091 11.9 0.1 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Glucosamine_iso PF01182.15 EGG09190.1 - 3.8e-42 144.2 0.0 4.8e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ribosomal_L6 PF00347.18 EGG09192.1 - 1e-14 54.7 0.0 2.4e-09 37.5 0.0 3.2 3 0 0 3 3 3 3 Ribosomal protein L6 HAD_2 PF13419.1 EGG09193.1 - 2.4e-16 60.4 0.0 3.8e-16 59.8 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase FAT PF02259.18 EGG09194.1 - 7.5e-63 212.6 11.2 1.7e-62 211.4 7.8 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EGG09194.1 - 8.9e-16 58.0 0.1 3.1e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EGG09194.1 - 5e-05 22.6 0.4 0.00022 20.5 0.2 2.2 1 0 0 1 1 1 1 FATC domain TPR_8 PF13181.1 EGG09194.1 - 0.0022 17.6 0.9 1.1 9.1 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGG09194.1 - 0.18 11.8 2.0 12 6.1 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat HI0933_like PF03486.9 EGG09194.1 - 0.54 8.6 0.0 6.7 5.0 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein TPR_12 PF13424.1 EGG09194.1 - 0.92 9.4 6.6 12 5.9 0.6 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TP6A_N PF04406.9 EGG09195.1 - 7.4e-20 70.3 0.2 7.4e-20 70.3 0.1 1.9 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 EGG09195.1 - 0.0053 16.6 0.1 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2399) DUF4218 PF13960.1 EGG09196.1 - 0.001 18.5 0.0 0.0022 17.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Dmrt1 PF12374.3 EGG09196.1 - 0.3 11.4 7.9 0.93 9.8 5.5 1.8 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 DUF2333 PF10095.4 EGG09197.1 - 0.09 11.4 0.0 0.19 10.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Asp PF00026.18 EGG09199.1 - 1.5e-108 362.7 0.0 1.9e-108 362.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG09199.1 - 2.6e-11 43.7 0.0 7.7e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EGG09199.1 - 2.5e-07 30.3 0.0 4.6e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EGG09199.1 - 0.00011 22.6 0.0 0.11 13.0 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease DUF3357 PF11837.3 EGG09202.1 - 0.086 12.6 0.0 0.086 12.6 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Nrf1_activ_bdg PF10492.4 EGG09203.1 - 0.26 11.7 0.1 0.26 11.7 0.1 2.2 2 0 0 2 2 2 0 Nrf1 activator activation site binding domain LAP1C PF05609.7 EGG09204.1 - 0.016 13.8 0.0 0.019 13.6 0.0 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Tryp_alpha_amyl PF00234.17 EGG09205.1 - 0.1 12.8 2.8 0.18 12.0 0.1 2.1 1 1 1 2 2 2 0 Protease inhibitor/seed storage/LTP family AATF-Che1 PF13339.1 EGG09210.1 - 0.015 15.4 4.5 0.015 15.4 3.1 2.5 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Hex_IIIa PF02455.11 EGG09210.1 - 0.18 10.4 11.7 0.29 9.7 8.1 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) KxDL PF10241.4 EGG09210.1 - 0.44 10.4 4.4 0.49 10.3 1.7 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein Peptidase_S64 PF08192.6 EGG09210.1 - 0.64 8.2 10.6 0.81 7.9 7.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Grp1_Fun34_YaaH PF01184.14 EGG09211.1 - 1.8e-80 269.1 14.2 2.3e-80 268.8 9.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family zf-DBF PF07535.7 EGG09211.1 - 0.13 11.9 0.7 0.21 11.2 0.5 1.2 1 0 0 1 1 1 0 DBF zinc finger DUF1467 PF07330.7 EGG09211.1 - 0.72 9.6 5.3 0.92 9.3 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) Lipase_GDSL_2 PF13472.1 EGG09212.1 - 4e-06 27.0 0.0 5.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family tRNA-synt_2 PF00152.15 EGG09213.1 - 6.7e-87 291.3 0.0 9.3e-87 290.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGG09213.1 - 2.8e-10 39.9 0.0 1.1e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGG09213.1 - 4.7e-08 32.5 0.0 0.00016 20.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EGG09213.1 - 0.021 14.4 0.0 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Ribonucleas_3_3 PF14622.1 EGG09214.1 - 5.6e-13 48.9 0.0 1.1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like CAP59_mtransfer PF11735.3 EGG09216.1 - 2.3e-39 135.0 0.0 3.7e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CDC45 PF02724.9 EGG09216.1 - 0.16 9.9 12.2 0.25 9.3 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein AT_hook PF02178.14 EGG09217.1 - 0.00019 20.6 12.0 0.002 17.6 1.3 2.6 2 0 0 2 2 2 2 AT hook motif Actino_peptide PF14408.1 EGG09217.1 - 4.4 7.2 6.6 0.37 10.7 0.7 2.1 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes Viral_DNA_bp PF00747.12 EGG09218.1 - 0.0013 16.1 0.2 0.0016 15.7 0.1 1.1 1 0 0 1 1 1 1 ssDNA binding protein NUDIX PF00293.23 EGG09220.1 - 3.8e-07 29.8 0.0 1.1e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 NUDIX domain Glyco_transf_25 PF01755.12 EGG09221.1 - 2e-15 57.0 0.4 2.4e-14 53.4 0.3 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) RGS PF00615.14 EGG09224.1 - 3.4e-05 23.9 0.7 0.13 12.3 0.2 2.5 2 1 0 2 2 2 2 Regulator of G protein signaling domain CRPA PF05745.6 EGG09224.1 - 0.56 9.9 3.2 1.7 8.4 0.1 2.3 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF4131 PF13567.1 EGG09224.1 - 7.6 5.9 6.6 3.4 7.0 2.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3348 PF11828.3 EGG09228.1 - 0.029 13.8 0.4 1.5 8.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3348) AIF_C PF14721.1 EGG09228.1 - 2 8.6 8.4 3 8.1 0.2 3.0 1 1 2 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1180 PF06679.7 EGG09228.1 - 8.6 6.2 9.6 1.8 8.4 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF4218 PF13960.1 EGG09229.1 - 0.0036 16.7 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF1106 PF06523.6 EGG09229.1 - 0.012 15.4 1.6 0.16 11.8 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1106) PXA PF02194.10 EGG09232.1 - 0.2 11.1 1.2 0.23 11.0 0.1 1.6 2 0 0 2 2 2 0 PXA domain GILT PF03227.11 EGG09233.1 - 2e-11 43.7 0.4 3.8e-11 42.8 0.3 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) PCI PF01399.22 EGG09234.1 - 2.6e-11 43.7 0.9 1e-10 41.8 0.0 2.5 3 1 0 3 3 3 1 PCI domain RPN7 PF10602.4 EGG09234.1 - 1.8e-06 27.4 1.3 5.1e-06 25.9 0.3 2.2 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_12 PF13424.1 EGG09234.1 - 0.026 14.4 1.2 0.68 9.9 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Antirestrict PF03230.8 EGG09234.1 - 0.032 14.2 0.0 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 Antirestriction protein TPR_14 PF13428.1 EGG09234.1 - 0.13 12.9 1.0 44 5.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat HCV_NS5a_C PF12941.2 EGG09238.1 - 0.0078 15.8 0.1 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 HCV NS5a protein C-terminal region DUF1770 PF08589.5 EGG09238.1 - 0.023 15.2 0.5 0.033 14.8 0.3 1.2 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) PBP1_TM PF14812.1 EGG09238.1 - 0.082 13.2 0.5 0.12 12.6 0.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Gon7 PF08738.5 EGG09241.1 - 0.047 13.6 1.1 1 9.4 0.0 2.6 2 0 0 2 2 2 0 Gon7 family Glyco_transf_90 PF05686.7 EGG09242.1 - 1.7e-35 122.5 0.9 2.8e-35 121.7 0.6 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 90 Peptidase_C12 PF01088.16 EGG09242.1 - 0.042 13.0 1.5 0.13 11.4 0.6 2.0 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 DHFR_1 PF00186.14 EGG09245.1 - 2.8e-27 95.2 0.1 4.6e-18 65.3 0.0 2.2 2 0 0 2 2 2 2 Dihydrofolate reductase TIMP PF00965.12 EGG09245.1 - 0.1 12.1 0.1 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase HABP4_PAI-RBP1 PF04774.10 EGG09249.1 - 0.084 13.3 0.9 0.24 11.9 0.0 2.1 2 1 0 2 2 2 0 Hyaluronan / mRNA binding family MAP65_ASE1 PF03999.7 EGG09249.1 - 1.2 7.6 6.3 1.4 7.3 4.4 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Planc_extracel PF07595.7 EGG09251.1 - 1.4e-07 30.8 4.4 36 4.2 0.0 7.2 6 0 0 6 6 6 6 Planctomycete extracellular Fungal_trans PF04082.13 EGG09252.1 - 2.7e-23 82.1 0.3 6.2e-23 80.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGG09252.1 - 0.009 15.9 13.2 0.009 15.9 9.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CALCOCO1 PF07888.6 EGG09253.1 - 0.029 12.6 0.0 0.035 12.4 0.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like tRNA-synt_2 PF00152.15 EGG09254.1 - 1.3e-72 244.4 0.0 1.7e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGG09254.1 - 1.2e-09 37.9 0.3 2.3e-09 36.9 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EGG09254.1 - 0.0076 15.8 0.2 0.024 14.2 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 EGG09254.1 - 0.028 13.6 0.0 3.4 6.7 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Toxin_7 PF05980.7 EGG09255.1 - 0.25 11.3 2.4 0.29 11.1 0.6 1.9 1 1 0 1 1 1 0 Toxin 7 LEDGF PF11467.3 EGG09257.1 - 0.029 14.0 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) Carbpep_Y_N PF05388.6 EGG09258.1 - 0.045 13.9 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide NPV_P10 PF05531.7 EGG09259.1 - 0.0022 18.2 1.4 0.0061 16.7 1.0 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF1993 PF09351.5 EGG09259.1 - 0.025 14.4 1.3 0.27 11.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Ribosomal_S14 PF00253.16 EGG09261.1 - 3.5e-15 55.1 0.1 5.4e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF1556 PF07590.6 EGG09261.1 - 0.12 12.6 1.0 0.15 12.2 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1556) Prok-E2_E PF14462.1 EGG09262.1 - 0.073 12.6 0.3 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family E CSD PF00313.17 EGG09263.1 - 6.4e-19 67.5 1.6 1.4e-18 66.3 0.9 1.8 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain Tht1 PF04163.7 EGG09264.1 - 0.046 12.1 0.3 0.059 11.7 0.2 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein zf-DHHC PF01529.15 EGG09265.1 - 1.3e-19 70.2 0.2 3.3e-19 68.9 0.0 1.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase SieB PF14163.1 EGG09265.1 - 0.16 11.5 0.8 11 5.5 0.2 2.2 2 0 0 2 2 2 0 Superinfection exclusion protein B KIAA1328 PF15369.1 EGG09267.1 - 6 6.5 8.6 19 4.9 5.9 1.8 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Actin PF00022.14 EGG09269.1 - 8.6e-131 435.9 0.0 1.4e-130 435.3 0.0 1.2 1 1 0 1 1 1 1 Actin Cutinase PF01083.17 EGG09270.1 - 1.5e-28 99.7 0.2 2e-28 99.3 0.2 1.1 1 0 0 1 1 1 1 Cutinase PGAP1 PF07819.8 EGG09270.1 - 0.0036 16.9 0.0 0.0051 16.4 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein VirJ PF06057.6 EGG09270.1 - 0.035 13.9 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_1 PF00561.15 EGG09270.1 - 0.058 12.9 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGG09270.1 - 0.072 12.9 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 EGG09270.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Cutinase PF01083.17 EGG09271.1 - 6.8e-30 104.1 0.5 8.8e-30 103.7 0.4 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 EGG09271.1 - 0.032 14.0 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 EGG09271.1 - 0.042 13.2 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.6 EGG09271.1 - 0.058 13.1 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) UPF0565 PF10561.4 EGG09271.1 - 0.15 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Asp PF00026.18 EGG09272.1 - 1.7e-20 73.5 0.1 4.5e-20 72.1 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG09272.1 - 0.00016 21.6 0.0 0.013 15.5 0.0 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal THOC7 PF05615.8 EGG09273.1 - 0.0074 16.5 7.5 0.63 10.3 1.2 2.4 2 0 0 2 2 2 2 Tho complex subunit 7 EBV-NA3 PF05009.7 EGG09273.1 - 0.19 10.9 1.1 0.33 10.1 0.8 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Mucin PF01456.12 EGG09273.1 - 0.81 9.4 5.7 1.5 8.5 4.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein HAUS-augmin3 PF14932.1 EGG09273.1 - 3.5 6.7 14.0 0.36 9.9 2.2 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 NADH_dehy_S2_C PF06444.6 EGG09274.1 - 0.13 12.5 0.1 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus TEBP_beta PF07404.6 EGG09275.1 - 0.015 14.5 0.0 0.017 14.2 0.0 1.0 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) DUF1213 PF06740.7 EGG09275.1 - 0.14 12.3 0.2 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1213) CDC50 PF03381.10 EGG09277.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family GRASP55_65 PF04495.9 EGG09278.1 - 4.7e-61 204.7 0.0 3.2e-44 150.2 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EGG09278.1 - 1e-06 28.5 0.0 0.00024 20.9 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 EGG09278.1 - 0.018 14.8 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 0 Tricorn protease PDZ domain BESS PF02944.15 EGG09280.1 - 2.2 7.8 19.4 18 4.9 0.1 6.1 5 1 1 6 6 6 0 BESS motif Ring_hydroxyl_B PF00866.13 EGG09281.1 - 0.08 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Ring hydroxylating beta subunit Thiolase_N PF00108.18 EGG09284.1 - 1.4e-76 256.9 0.0 1.8e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGG09284.1 - 2.1e-45 153.1 0.3 4.3e-45 152.1 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGG09284.1 - 0.00041 19.8 0.0 0.00081 18.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AA_permease_2 PF13520.1 EGG09285.1 - 5.3e-55 186.6 51.4 6.5e-55 186.3 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGG09285.1 - 4.2e-20 71.5 41.8 5.6e-20 71.1 29.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2098 PF09871.4 EGG09286.1 - 0.026 14.4 2.7 0.081 12.8 1.9 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) RNase_T PF00929.19 EGG09287.1 - 3.8e-28 98.8 0.0 6.8e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EGG09287.1 - 0.0048 16.4 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease C-term_anchor PF13461.1 EGG09287.1 - 0.44 11.0 0.1 0.44 11.0 0.1 2.2 3 0 0 3 3 3 0 Cell-wall surface anchor repeat BAR PF03114.13 EGG09288.1 - 9.1e-56 188.9 2.2 1.1e-55 188.6 1.5 1.1 1 0 0 1 1 1 1 BAR domain Vps5 PF09325.5 EGG09288.1 - 0.0056 15.9 1.1 1.1 8.4 0.6 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Arfaptin PF06456.8 EGG09288.1 - 0.016 14.5 5.5 0.19 11.0 3.8 2.0 1 1 0 1 1 1 0 Arfaptin-like domain Chalcone PF02431.10 EGG09289.1 - 1.9e-44 151.4 0.0 2.8e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Alpha-L-AF_C PF06964.7 EGG09290.1 - 4.6e-31 107.9 0.0 8.9e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Lipoprotein_17 PF04200.7 EGG09291.1 - 0.06 13.4 0.4 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 Lipoprotein associated domain GrpE PF01025.14 EGG09293.1 - 0.095 12.2 0.4 1 8.8 0.0 2.6 3 0 0 3 3 3 0 GrpE PCI PF01399.22 EGG09295.1 - 7.2e-18 64.8 0.0 9.5e-17 61.2 0.0 2.7 2 1 0 2 2 2 1 PCI domain Syntaxin_2 PF14523.1 EGG09295.1 - 0.048 13.7 1.6 0.69 9.9 1.0 2.6 1 1 1 2 2 2 0 Syntaxin-like protein RRM_1 PF00076.17 EGG09296.1 - 2e-18 65.8 0.0 3.1e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG09296.1 - 3.3e-13 49.3 0.0 5.6e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG09296.1 - 2.8e-08 33.4 0.0 4.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EGG09296.1 - 2.4e-06 27.8 0.4 2.4e-06 27.8 0.3 2.6 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Smg4_UPF3 PF03467.10 EGG09296.1 - 0.07 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family BNR_2 PF13088.1 EGG09296.1 - 0.099 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 BNR repeat-like domain MRP-S33 PF08293.6 EGG09297.1 - 3.2e-11 43.0 0.1 3.5e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 SNF5 PF04855.7 EGG09299.1 - 3.4e-64 216.6 1.1 7e-64 215.6 0.8 1.4 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 TolB_N PF04052.8 EGG09299.1 - 0.033 14.2 0.0 0.062 13.3 0.0 1.5 1 1 0 1 1 1 0 TolB amino-terminal domain tRNA-synt_1b PF00579.20 EGG09300.1 - 7.4e-67 225.5 0.0 1.1e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 EGG09300.1 - 0.084 12.3 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 S4 domain GASA PF02704.9 EGG09301.1 - 0.041 13.8 1.3 0.082 12.8 0.4 1.8 1 1 1 2 2 2 0 Gibberellin regulated protein V-SNARE PF05008.10 EGG09303.1 - 0.016 15.3 0.8 0.035 14.2 0.6 1.6 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus CTDII PF01556.13 EGG09304.1 - 4.7e-31 106.5 1.2 7.4e-23 80.2 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EGG09304.1 - 2.7e-23 81.4 2.3 4.3e-23 80.8 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGG09304.1 - 2.3e-11 43.5 16.5 4.5e-11 42.6 11.4 1.5 1 0 0 1 1 1 1 DnaJ central domain DUF4309 PF14172.1 EGG09304.1 - 0.14 12.1 0.2 0.25 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) HypA PF01155.14 EGG09304.1 - 2.2 8.0 9.8 3.1 7.4 1.3 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family O-FucT PF10250.4 EGG09305.1 - 8.9e-06 25.0 0.0 0.025 13.6 0.0 3.0 3 0 0 3 3 3 2 GDP-fucose protein O-fucosyltransferase Glyco_hydro_16 PF00722.16 EGG09306.1 - 2.6e-07 30.0 0.1 5e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 IPK PF03770.11 EGG09308.1 - 7.2e-34 117.1 0.0 7.4e-33 113.8 0.0 2.0 1 1 0 1 1 1 1 Inositol polyphosphate kinase zf-C2H2_3 PF13878.1 EGG09309.1 - 0.29 10.7 1.9 0.31 10.6 0.3 1.8 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Phosphodiest PF01663.17 EGG09310.1 - 5.7e-11 42.3 0.3 9.5e-11 41.6 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EGG09310.1 - 0.019 14.3 0.2 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Mito_carr PF00153.22 EGG09311.1 - 2.5e-54 180.9 1.2 5.6e-17 61.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4333 PF14230.1 EGG09312.1 - 0.1 12.6 1.0 1.8 8.5 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4333) Connexin_CCC PF10582.4 EGG09312.1 - 0.18 11.6 1.4 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Gap junction channel protein cysteine-rich domain COG4 PF08318.7 EGG09313.1 - 2.8e-11 42.7 0.1 0.00012 20.9 0.0 2.2 2 0 0 2 2 2 2 COG4 transport protein Sdh5 PF03937.11 EGG09314.1 - 0.037 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Med4 PF10018.4 EGG09316.1 - 0.0033 16.8 0.9 0.0033 16.8 0.6 1.7 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF342 PF03961.8 EGG09316.1 - 0.016 13.6 1.3 0.022 13.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cep57_CLD_2 PF14197.1 EGG09316.1 - 0.048 13.6 0.9 0.048 13.6 0.6 2.3 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Fmp27_WPPW PF10359.4 EGG09316.1 - 0.068 11.5 2.5 0.097 11.0 1.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HalX PF08663.5 EGG09316.1 - 0.27 11.2 3.2 0.76 9.8 1.8 2.0 1 1 0 1 1 1 0 HalX domain Mnd1 PF03962.10 EGG09316.1 - 0.43 10.2 7.4 0.73 9.4 5.1 1.3 1 0 0 1 1 1 0 Mnd1 family Zn_clus PF00172.13 EGG09318.1 - 0.05 13.5 1.8 0.081 12.8 1.2 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_Tnp_IS1595 PF12760.2 EGG09318.1 - 0.21 11.4 3.5 0.37 10.6 2.4 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain FoP_duplication PF13865.1 EGG09319.1 - 0.00036 20.9 0.1 0.00062 20.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 SLAC1 PF03595.12 EGG09321.1 - 4.1e-21 74.9 24.0 5.1e-21 74.6 16.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Gram_pos_anchor PF00746.16 EGG09321.1 - 0.13 12.0 2.1 0.46 10.3 1.5 2.0 1 0 0 1 1 1 0 Gram positive anchor DUF3917 PF13055.1 EGG09321.1 - 0.27 11.5 4.4 10 6.4 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3917) Fig1 PF12351.3 EGG09321.1 - 2 8.2 6.5 1.2 8.9 1.3 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Glyco_hydro_7 PF00840.15 EGG09322.1 - 0.12 10.7 2.0 0.18 10.1 1.4 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 zinc_ribbon_2 PF13240.1 EGG09323.1 - 0.2 11.1 1.0 2 8.0 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Alpha_kinase PF02816.13 EGG09325.1 - 1.9e-06 27.7 0.3 5e-05 23.0 0.1 2.5 2 0 0 2 2 2 1 Alpha-kinase family CI-B14_5a PF07347.7 EGG09325.1 - 0.022 14.5 0.1 0.062 13.0 0.0 1.8 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Ribonuc_red_lgN PF00317.16 EGG09327.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain HMG_box_2 PF09011.5 EGG09328.1 - 0.016 15.5 0.1 0.045 14.1 0.0 1.7 1 0 0 1 1 1 0 HMG-box domain zf-CCHC PF00098.18 EGG09329.1 - 0.0032 17.3 2.6 0.0059 16.4 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGG09329.1 - 0.12 12.0 2.7 0.2 11.3 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle SAG PF04092.8 EGG09333.1 - 0.06 13.7 2.5 0.065 13.6 1.7 1.0 1 0 0 1 1 1 0 SRS domain DUF4596 PF15363.1 EGG09333.1 - 0.068 13.0 0.1 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Rtt106 PF08512.7 EGG09334.1 - 0.14 12.1 0.3 0.24 11.4 0.2 1.3 1 0 0 1 1 1 0 Histone chaperone Rttp106-like PAP2 PF01569.16 EGG09335.1 - 1.3e-09 37.8 5.0 2e-09 37.2 3.5 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 EGG09335.1 - 0.017 14.8 0.5 0.089 12.5 0.1 2.2 2 0 0 2 2 2 0 Divergent PAP2 family BTB PF00651.26 EGG09336.1 - 0.012 15.6 0.0 11 6.0 0.0 3.2 3 0 0 3 3 3 0 BTB/POZ domain CFEM PF05730.6 EGG09337.1 - 4.6e-12 45.5 9.6 5.4e-12 45.3 6.7 1.1 1 0 0 1 1 1 1 CFEM domain Pex14_N PF04695.8 EGG09339.1 - 0.049 13.6 0.9 0.081 12.9 0.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mucin PF01456.12 EGG09339.1 - 0.98 9.1 13.2 1.4 8.6 9.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Choline_transpo PF04515.7 EGG09340.1 - 1.4e-07 30.6 1.0 1.5e-07 30.5 0.7 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF2842 PF11003.3 EGG09340.1 - 0.14 12.0 0.5 0.22 11.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) NOA36 PF06524.7 EGG09341.1 - 0.49 9.6 5.0 0.61 9.2 3.5 1.0 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 EGG09341.1 - 0.99 7.3 7.4 1.2 7.0 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4551 PF15087.1 EGG09341.1 - 6.1 5.0 14.3 7.3 4.8 9.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PilX PF13681.1 EGG09342.1 - 0.041 14.3 1.4 0.2 12.1 0.6 2.1 1 1 1 2 2 2 0 Type IV pilus assembly protein PilX C-term Urm1 PF09138.6 EGG09345.1 - 1.2e-19 70.2 0.0 1.4e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EGG09345.1 - 0.12 12.8 0.0 0.15 12.5 0.0 1.4 1 1 0 1 1 1 0 ThiS family Aconitase PF00330.15 EGG09347.1 - 0.0099 14.3 0.1 0.013 14.0 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) ABA_GPCR PF12430.3 EGG09348.1 - 6.3e-20 71.1 17.4 2.7e-16 59.2 4.7 2.8 2 1 1 3 3 3 2 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EGG09348.1 - 5.6e-11 42.3 0.0 2.1e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) CAP PF00188.21 EGG09350.1 - 5.3e-15 56.0 0.9 5.3e-15 56.0 0.6 2.3 3 0 0 3 3 3 1 Cysteine-rich secretory protein family Daxx PF03344.10 EGG09350.1 - 0.035 12.5 53.6 0.051 12.0 37.1 1.2 1 0 0 1 1 1 0 Daxx Family RRM_1 PF00076.17 EGG09351.1 - 1.2e-15 56.8 0.0 1.8e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG09351.1 - 5.2e-15 55.0 0.0 7.8e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG09351.1 - 7e-15 54.7 0.0 1.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2474 PF10617.4 EGG09353.1 - 0.16 11.5 0.9 0.35 10.4 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) NAM-associated PF14303.1 EGG09354.1 - 0.022 15.0 4.6 0.043 14.1 3.2 1.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain YebO PF13974.1 EGG09354.1 - 0.024 14.4 0.7 0.031 14.0 0.2 1.5 1 1 1 2 2 2 0 YebO-like protein CARD PF00619.16 EGG09355.1 - 0.063 13.1 0.2 0.095 12.5 0.1 1.3 1 0 0 1 1 1 0 Caspase recruitment domain CBP4 PF07960.6 EGG09357.1 - 0.0015 18.1 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 CBP4 Ribosomal_L18e PF00828.14 EGG09358.1 - 1.7e-21 76.9 0.0 1.7e-21 76.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 WW PF00397.21 EGG09360.1 - 0.044 13.6 0.8 0.044 13.6 0.6 2.4 3 0 0 3 3 3 0 WW domain BCDHK_Adom3 PF10436.4 EGG09361.1 - 3.5e-20 72.1 0.1 6.5e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF486 PF04342.7 EGG09361.1 - 0.094 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF486 GPP34 PF05719.6 EGG09362.1 - 2.7e-64 217.0 0.0 3.4e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Sushi PF00084.15 EGG09364.1 - 0.21 11.9 2.3 0.31 11.3 1.6 1.2 1 0 0 1 1 1 0 Sushi domain (SCR repeat) FAD_binding_7 PF03441.9 EGG09365.1 - 6.3e-94 314.2 0.0 9.4e-94 313.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EGG09365.1 - 1.2e-37 129.2 0.3 2.2e-37 128.3 0.2 1.4 1 0 0 1 1 1 1 DNA photolyase Alpha_kinase PF02816.13 EGG09366.1 - 4.3e-11 42.8 0.4 7e-11 42.1 0.3 1.3 1 1 0 1 1 1 1 Alpha-kinase family ATG16 PF08614.6 EGG09367.1 - 0.0012 18.6 18.9 0.0015 18.3 10.4 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) NPV_P10 PF05531.7 EGG09367.1 - 0.0014 18.8 6.5 0.021 15.0 0.1 3.9 3 2 0 3 3 3 1 Nucleopolyhedrovirus P10 protein zf-C4H2 PF10146.4 EGG09367.1 - 0.0036 17.3 8.1 0.0036 17.3 5.6 2.2 1 1 1 2 2 2 1 Zinc finger-containing protein Reo_sigmaC PF04582.7 EGG09367.1 - 0.0084 15.3 0.4 0.024 13.8 0.1 1.8 1 1 0 1 1 1 1 Reovirus sigma C capsid protein Med9 PF07544.8 EGG09367.1 - 0.036 13.7 11.3 0.11 12.2 2.1 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Laminin_II PF06009.7 EGG09367.1 - 0.038 13.7 0.8 0.038 13.7 0.6 3.0 2 1 1 3 3 3 0 Laminin Domain II Baculo_PEP_C PF04513.7 EGG09367.1 - 0.057 13.2 6.6 1.3 8.8 0.2 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lyase_8_N PF08124.6 EGG09367.1 - 0.092 11.6 1.1 0.18 10.6 0.7 1.5 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Phage_GPO PF05929.6 EGG09367.1 - 0.23 10.6 6.3 0.083 12.1 1.5 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase V_ATPase_I PF01496.14 EGG09367.1 - 0.29 8.9 8.5 0.49 8.1 5.8 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DDE_Tnp_IS66 PF03050.9 EGG09367.1 - 0.36 10.0 9.6 0.28 10.3 1.0 2.3 3 0 0 3 3 3 0 Transposase IS66 family FlaC_arch PF05377.6 EGG09367.1 - 0.6 10.0 0.0 0.6 10.0 0.0 3.5 4 1 0 4 4 3 0 Flagella accessory protein C (FlaC) DUF4279 PF14106.1 EGG09367.1 - 0.65 9.8 3.5 9.2 6.1 0.1 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4279) DUF2347 PF09804.4 EGG09367.1 - 0.75 9.0 4.3 1.1 8.4 2.5 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) IncA PF04156.9 EGG09367.1 - 1.1 8.8 27.1 1.1e+02 2.3 16.0 3.2 2 1 0 2 2 2 0 IncA protein Allexi_40kDa PF05549.6 EGG09367.1 - 1.5 8.0 12.5 0.11 11.7 2.6 2.5 1 1 2 3 3 3 0 Allexivirus 40kDa protein DUF883 PF05957.8 EGG09367.1 - 3.1 8.2 8.1 16 6.0 0.7 3.4 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) CorA PF01544.13 EGG09367.1 - 9.7 5.1 9.7 1.8 7.5 0.8 2.0 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Sad1_UNC PF07738.8 EGG09368.1 - 5.3e-29 100.7 0.1 8.7e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal UreD PF01774.12 EGG09368.1 - 0.097 12.1 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 UreD urease accessory protein BCNT PF07572.7 EGG09369.1 - 6 6.8 10.9 14 5.6 7.6 1.5 1 1 0 1 1 1 0 Bucentaur or craniofacial development CDC45 PF02724.9 EGG09372.1 - 0.54 8.2 14.5 1.1 7.1 10.1 1.5 1 0 0 1 1 1 0 CDC45-like protein CENP-F_leu_zip PF10473.4 EGG09374.1 - 0.024 14.4 5.6 0.024 14.4 3.8 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.11 EGG09374.1 - 0.04 13.9 2.8 0.076 13.0 1.8 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein TMCO5 PF14992.1 EGG09374.1 - 0.043 12.9 5.2 0.079 12.0 3.6 1.3 1 0 0 1 1 1 0 TMCO5 family CHDCT2 PF08074.6 EGG09374.1 - 0.052 13.2 0.2 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain NPV_P10 PF05531.7 EGG09374.1 - 0.14 12.3 4.9 0.1 12.8 0.7 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1902 PF08972.6 EGG09374.1 - 0.15 11.6 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) SlyX PF04102.7 EGG09374.1 - 1.4 9.3 8.1 0.095 13.0 1.1 2.5 3 0 0 3 3 3 0 SlyX His_Phos_2 PF00328.17 EGG09376.1 - 1.8e-43 149.1 0.0 2.3e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) bPH_6 PF10756.4 EGG09377.1 - 0.019 14.8 4.6 18 5.2 0.1 4.1 1 1 2 3 3 3 0 Bacterial PH domain Med19 PF10278.4 EGG09377.1 - 0.52 9.9 31.6 2 8.0 15.6 2.3 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.9 EGG09377.1 - 4.8 5.1 12.6 7.1 4.5 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Imm30 PF15594.1 EGG09378.1 - 0.026 14.5 0.1 0.063 13.3 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 30 PSK_trans_fac PF07704.6 EGG09380.1 - 0.058 14.0 1.4 0.058 14.0 1.0 1.7 2 0 0 2 2 2 0 Rv0623-like transcription factor Pkinase PF00069.20 EGG09381.1 - 3.5e-10 39.4 0.1 1.4e-09 37.4 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG09381.1 - 0.0029 16.7 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GPW_gp25 PF04965.9 EGG09385.1 - 0.068 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Gene 25-like lysozyme Metallophos PF00149.23 EGG09389.1 - 1.6e-42 145.1 0.9 2e-42 144.8 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3827 PF12877.2 EGG09390.1 - 2 6.3 10.7 2.6 6.0 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SRP-alpha_N PF04086.8 EGG09390.1 - 6.9 5.9 14.5 8.2 5.7 10.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Glyco_hydro_26 PF02156.10 EGG09395.1 - 1.1e-15 57.9 0.9 1.4e-15 57.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 LMWPc PF01451.16 EGG09399.1 - 5.4e-29 101.2 0.1 8.6e-29 100.6 0.0 1.2 2 0 0 2 2 2 1 Low molecular weight phosphotyrosine protein phosphatase F-box-like PF12937.2 EGG09400.1 - 0.00047 19.8 0.6 0.056 13.1 0.4 2.9 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGG09400.1 - 0.0018 17.8 3.0 0.55 9.9 0.2 4.1 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG09400.1 - 0.024 14.3 7.0 7.4 6.4 0.0 4.5 3 2 1 4 4 4 0 Leucine rich repeat Ldh_1_C PF02866.13 EGG09401.1 - 1.8e-13 50.6 0.0 2.1e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain adh_short PF00106.20 EGG09402.1 - 2.9e-20 72.8 0.0 7.7e-20 71.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG09402.1 - 2.1e-18 66.9 0.0 3.2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG09402.1 - 1.8e-06 27.7 0.0 5.7e-06 26.1 0.0 1.7 1 1 1 2 2 2 1 KR domain Shikimate_DH PF01488.15 EGG09402.1 - 0.0019 18.2 0.2 0.0043 17.1 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EGG09402.1 - 0.0072 15.9 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 EGG09402.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_10 PF13460.1 EGG09402.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGG09402.1 - 0.012 14.5 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.5 EGG09402.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_7 PF13241.1 EGG09402.1 - 0.031 14.5 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Epimerase PF01370.16 EGG09402.1 - 0.031 13.7 0.1 0.13 11.6 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.18 EGG09402.1 - 0.075 12.7 0.0 0.67 9.6 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 EGG09402.1 - 0.11 11.5 0.2 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain zf-H2C2_2 PF13465.1 EGG09403.1 - 3.3e-07 30.2 3.6 3.3e-07 30.2 2.5 3.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGG09403.1 - 0.00096 19.3 3.0 0.00096 19.3 2.1 3.2 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG09403.1 - 0.0023 18.1 2.4 0.0023 18.1 1.7 2.5 2 1 0 2 2 2 1 C2H2-type zinc finger Translat_reg PF01818.12 EGG09406.1 - 0.074 12.5 0.2 0.085 12.3 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage translational regulator DUF746 PF05344.6 EGG09406.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Chordopox_E11 PF06138.7 EGG09409.1 - 0.0015 18.5 1.2 0.0018 18.3 0.8 1.1 1 0 0 1 1 1 1 Chordopoxvirus E11 protein Glyco_hydro_12 PF01670.11 EGG09410.1 - 3.2e-23 82.2 0.2 6.7e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF2670 PF10875.3 EGG09411.1 - 0.041 13.9 0.1 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) DUF702 PF05142.7 EGG09411.1 - 7.4 6.7 8.7 0.94 9.6 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF702) G-alpha PF00503.15 EGG09413.1 - 1.4e-126 422.3 0.1 1.5e-126 422.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGG09413.1 - 1.9e-16 59.7 0.1 4.7e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGG09413.1 - 3.4e-05 23.1 0.2 0.18 10.8 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EGG09413.1 - 0.0025 18.3 0.3 0.84 10.1 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 EGG09413.1 - 0.027 13.9 0.0 0.78 9.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EGG09413.1 - 0.029 13.8 0.1 0.089 12.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4114 PF13448.1 EGG09414.1 - 0.049 14.4 0.0 0.094 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) GlgS PF08971.6 EGG09416.1 - 0.06 13.2 1.5 0.083 12.8 0.1 1.9 2 0 0 2 2 2 0 Glycogen synthesis protein ICEA PF05315.6 EGG09416.1 - 0.12 11.6 2.1 0.12 11.6 0.4 1.7 2 0 0 2 2 2 0 ICEA Protein DUF3315 PF11776.3 EGG09417.1 - 0.016 14.7 0.1 7.2 6.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3315) ROKNT PF08067.6 EGG09417.1 - 0.47 10.3 1.4 18 5.3 0.0 2.9 3 0 0 3 3 3 0 ROKNT (NUC014) domain NRDE PF05742.7 EGG09418.1 - 8e-31 107.3 4.5 3.8e-30 105.1 3.1 1.8 1 1 0 1 1 1 1 NRDE protein GBP_repeat PF02526.9 EGG09418.1 - 0.083 12.2 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Glycophorin-binding protein E1-E2_ATPase PF00122.15 EGG09421.1 - 8.8e-73 244.1 3.3 8.8e-73 244.1 2.3 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGG09421.1 - 2.1e-34 118.6 2.8 2.1e-34 118.6 1.9 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGG09421.1 - 1.6e-31 110.4 0.0 4.7e-31 108.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGG09421.1 - 6.9e-16 58.9 0.0 1.4e-15 57.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGG09421.1 - 2.5e-10 40.1 0.0 5.2e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGG09421.1 - 3.7e-07 29.4 0.0 1e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGG09421.1 - 0.00024 20.7 2.9 0.0048 16.5 0.7 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2570 PF10828.3 EGG09422.1 - 0.00094 18.7 0.9 0.002 17.7 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) Myb_DNA-bind_4 PF13837.1 EGG09422.1 - 0.012 15.6 1.2 0.03 14.4 0.1 2.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain SNARE PF05739.14 EGG09424.1 - 9.1e-08 31.6 0.1 1.1e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 SNARE domain Sec20 PF03908.8 EGG09424.1 - 0.011 15.4 0.9 0.02 14.6 0.6 1.5 1 1 0 1 1 1 0 Sec20 Use1 PF09753.4 EGG09424.1 - 0.021 14.2 0.9 0.024 14.1 0.6 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Corona_S2 PF01601.11 EGG09424.1 - 0.026 12.6 1.2 0.026 12.6 0.8 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF3753 PF12575.3 EGG09424.1 - 0.15 11.8 1.3 0.24 11.2 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3753) Chitin_synth_1N PF08407.6 EGG09425.1 - 9.6e-17 60.4 0.0 1.3e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase N-terminal DLH PF01738.13 EGG09426.1 - 2.9e-18 65.9 0.0 4e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EGG09426.1 - 0.002 17.7 0.0 0.01 15.4 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG09426.1 - 0.062 13.0 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Dynactin_p22 PF07426.6 EGG09426.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Dynactin subunit p22 FMN_dh PF01070.13 EGG09427.1 - 3.2e-118 394.6 0.0 4e-118 394.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EGG09427.1 - 6.6e-21 73.9 0.0 2.8e-20 71.9 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EGG09427.1 - 3.2e-05 23.0 0.0 9.4e-05 21.4 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 EGG09427.1 - 9.1e-05 21.5 0.0 0.00019 20.4 0.0 1.5 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EGG09427.1 - 0.022 13.9 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.9 EGG09427.1 - 0.042 12.9 0.0 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EGG09427.1 - 0.047 12.9 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein zf-RING_2 PF13639.1 EGG09428.1 - 8.2e-09 35.1 8.6 8.2e-09 35.1 6.0 2.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EGG09428.1 - 1.8e-08 33.8 9.6 5.2e-08 32.4 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG09428.1 - 4e-08 33.1 10.5 1.1e-07 31.6 7.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG09428.1 - 4.1e-08 32.7 6.2 9.3e-08 31.6 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG09428.1 - 0.00074 19.1 8.1 0.0018 17.9 5.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGG09428.1 - 0.025 14.6 11.1 0.026 14.6 5.3 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGG09428.1 - 1.7 8.5 9.2 5.8 6.8 6.4 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SNAP PF14938.1 EGG09431.1 - 2.6e-106 354.9 9.4 2.9e-106 354.7 6.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Spatacsin_C PF14649.1 EGG09431.1 - 1.8e-05 23.7 1.7 0.00025 20.0 1.1 2.3 1 1 1 2 2 2 2 Spatacsin C-terminus TPR_2 PF07719.12 EGG09431.1 - 0.0025 17.6 9.5 7.5 6.7 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EGG09431.1 - 0.0038 17.3 3.7 1.3 9.2 0.2 2.8 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF410 PF04190.8 EGG09431.1 - 0.036 13.6 0.6 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF410) TPR_6 PF13174.1 EGG09431.1 - 0.052 14.0 1.1 1.6e+02 3.0 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGG09431.1 - 0.062 13.9 3.7 43 4.9 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGG09431.1 - 0.083 13.2 6.3 2.3 8.6 0.1 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGG09431.1 - 0.58 10.1 8.0 5.7 6.9 1.3 3.3 2 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGG09431.1 - 1.5 8.8 4.2 17 5.5 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.12 EGG09432.1 - 2e-43 148.5 1.3 2.6e-43 148.2 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Ribosomal_L33 PF00471.15 EGG09435.1 - 3.5e-07 30.3 0.0 7.4e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L33 Chorion_1 PF01723.11 EGG09438.1 - 0.013 15.4 1.2 0.015 15.1 0.2 1.7 1 1 1 2 2 2 0 Chorion protein HEAT_EZ PF13513.1 EGG09439.1 - 1e-24 86.3 19.0 3.1e-10 40.2 0.1 11.5 11 1 1 12 12 11 3 HEAT-like repeat HEAT PF02985.17 EGG09439.1 - 1.2e-21 74.7 8.4 0.00037 20.3 0.0 9.2 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 EGG09439.1 - 6.4e-18 64.8 0.0 1.8e-05 24.9 0.0 6.1 4 4 1 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EGG09439.1 - 2e-05 24.9 0.0 0.21 12.0 0.0 4.9 4 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EGG09439.1 - 2.8e-05 23.9 0.0 0.00084 19.2 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 EGG09439.1 - 4.1e-05 22.0 0.0 0.0089 14.3 0.0 3.2 2 1 1 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.2 EGG09439.1 - 0.0001 22.2 0.1 1 9.2 0.0 5.0 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 UNC45-central PF11701.3 EGG09439.1 - 0.0021 17.7 0.1 0.046 13.3 0.0 2.5 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central Arm PF00514.18 EGG09439.1 - 0.0023 17.6 12.0 1.7 8.6 0.1 6.7 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Xpo1 PF08389.7 EGG09439.1 - 0.0028 17.5 0.5 0.29 11.0 0.0 3.6 5 0 0 5 5 5 1 Exportin 1-like protein MMS19_C PF12460.3 EGG09439.1 - 0.061 12.0 4.2 0.78 8.4 0.1 3.6 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 EGG09439.1 - 0.15 11.3 0.0 7 5.9 0.0 3.6 4 1 0 4 4 4 0 CLASP N terminal LRR_9 PF14580.1 EGG09441.1 - 0.00056 19.5 0.5 0.0015 18.1 0.3 1.7 1 0 0 1 1 1 1 Leucine-rich repeat F-box PF00646.28 EGG09441.1 - 0.015 14.9 0.1 0.11 12.2 0.0 2.5 2 0 0 2 2 2 0 F-box domain Kunitz_BPTI PF00014.18 EGG09442.1 - 0.012 15.8 1.8 0.018 15.2 1.2 1.5 1 1 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Acyl_transf_3 PF01757.17 EGG09444.1 - 2.6e-27 95.5 28.8 4.2e-27 94.8 19.9 1.4 1 1 0 1 1 1 1 Acyltransferase family RRN3 PF05327.6 EGG09445.1 - 4.5e-132 441.0 0.0 5.5e-132 440.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 IDO PF01231.13 EGG09446.1 - 8.2e-43 146.4 0.0 1.1e-42 146.0 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TPR_11 PF13414.1 EGG09447.1 - 7.1e-14 51.2 8.7 4.1e-07 29.5 0.1 3.2 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EGG09447.1 - 8.8e-12 43.9 5.1 0.012 15.4 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.19 EGG09447.1 - 1.1e-11 44.1 0.0 1.9e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.23 EGG09447.1 - 3.1e-07 29.7 6.2 0.0037 16.8 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG09447.1 - 3.4e-07 30.1 2.0 6e-05 22.8 0.1 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGG09447.1 - 2.4e-05 23.7 0.7 0.025 14.3 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGG09447.1 - 0.0023 18.2 1.6 20 5.9 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGG09447.1 - 0.019 14.7 4.1 3 7.8 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGG09447.1 - 0.072 12.3 2.3 4.9 6.4 0.0 3.0 3 0 0 3 3 3 0 SHNi-TPR TPR_16 PF13432.1 EGG09447.1 - 0.13 12.9 7.7 0.1 13.3 0.8 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Paralemmin PF03285.10 EGG09449.1 - 0.0086 15.5 4.8 0.022 14.2 3.3 1.7 1 1 0 1 1 1 1 Paralemmin IncA PF04156.9 EGG09449.1 - 0.011 15.3 5.8 0.025 14.1 4.0 1.5 1 0 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 EGG09449.1 - 0.022 13.9 0.5 0.042 13.0 0.3 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Fmp27_WPPW PF10359.4 EGG09449.1 - 0.023 13.1 1.8 0.032 12.6 1.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF711 PF05167.7 EGG09449.1 - 0.031 13.0 0.2 0.043 12.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) CR6_interact PF10147.4 EGG09449.1 - 0.037 13.3 3.5 0.17 11.1 1.9 2.0 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Atg14 PF10186.4 EGG09449.1 - 0.046 12.6 3.9 0.074 11.9 2.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 EGG09449.1 - 0.16 12.2 4.7 0.21 11.8 0.5 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Sugarporin_N PF11471.3 EGG09449.1 - 0.16 11.6 3.7 0.34 10.5 2.5 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Methyltransf_18 PF12847.2 EGG09449.1 - 0.23 12.0 1.5 1.3 9.6 0.9 2.2 2 1 0 2 2 1 0 Methyltransferase domain DUF1664 PF07889.7 EGG09449.1 - 0.25 11.1 2.6 0.53 10.0 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF745 PF05335.8 EGG09449.1 - 0.25 10.8 4.0 0.49 9.8 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.2 EGG09449.1 - 0.28 11.0 10.0 0.63 9.8 6.9 1.6 1 1 0 1 1 1 0 Tropomyosin like Mnd1 PF03962.10 EGG09449.1 - 0.51 9.9 4.5 0.89 9.1 3.1 1.3 1 0 0 1 1 1 0 Mnd1 family BMFP PF04380.8 EGG09449.1 - 0.63 10.2 8.6 0.66 10.1 0.2 2.7 2 0 0 2 2 2 0 Membrane fusogenic activity SlyX PF04102.7 EGG09449.1 - 0.7 10.3 7.8 6.4 7.2 5.5 2.4 1 1 0 1 1 1 0 SlyX ADIP PF11559.3 EGG09449.1 - 0.8 9.5 9.0 2.8 7.8 0.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EGG09449.1 - 2.4 7.1 5.7 3.3 6.6 4.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Bap31 PF05529.7 EGG09449.1 - 2.7 7.3 5.6 2.6 7.4 2.6 1.9 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like XhlA PF10779.4 EGG09449.1 - 3 7.8 5.7 31 4.5 4.0 2.4 1 1 0 1 1 1 0 Haemolysin XhlA Prenyltrans PF00432.16 EGG09451.1 - 3.5e-13 48.8 0.0 6e-08 32.1 0.0 2.9 3 0 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGG09451.1 - 3.7e-10 40.2 0.0 4.6e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGG09451.1 - 0.00064 19.7 0.0 0.037 14.0 0.0 1.5 1 1 1 2 2 2 2 Prenyltransferase-like AFT PF08731.6 EGG09456.1 - 5.2e-06 26.6 0.4 1.5e-05 25.0 0.2 1.8 1 0 0 1 1 1 1 Transcription factor AFT FAR1 PF03101.10 EGG09456.1 - 0.003 18.0 0.7 0.0073 16.7 0.5 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain UPF0227 PF05728.7 EGG09457.1 - 0.023 14.4 0.7 0.05 13.3 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) UPF0242 PF06785.6 EGG09457.1 - 0.17 10.5 2.8 0.22 10.1 1.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) NPV_P10 PF05531.7 EGG09458.1 - 0.018 15.2 1.2 0.042 14.0 0.8 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein NST1 PF13945.1 EGG09459.1 - 2.3 8.2 8.5 0.17 11.9 1.3 2.0 2 0 0 2 2 2 0 Salt tolerance down-regulator CFEM PF05730.6 EGG09460.1 - 7.3e-13 48.1 9.4 1.5e-12 47.1 6.5 1.5 1 0 0 1 1 1 1 CFEM domain DUF4349 PF14257.1 EGG09462.1 - 0.0016 17.7 0.7 0.0028 16.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) Atg14 PF10186.4 EGG09462.1 - 0.046 12.6 4.6 0.068 12.1 3.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FTA4 PF13093.1 EGG09462.1 - 0.095 12.1 3.2 0.26 10.6 2.1 1.8 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GAS PF13851.1 EGG09462.1 - 0.88 8.7 5.3 0.19 10.9 1.1 1.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EGG09462.1 - 1 7.1 3.1 1.5 6.5 2.2 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TraA PF05513.6 EGG09464.1 - 0.081 13.0 1.2 0.49 10.5 0.8 1.9 1 1 0 1 1 1 0 TraA Ecl1 PF12855.2 EGG09465.1 - 0.0079 15.4 2.3 0.02 14.1 1.6 1.7 1 0 0 1 1 1 1 Life-span regulatory factor XPA_C PF05181.7 EGG09465.1 - 0.15 11.6 0.2 0.63 9.6 0.0 2.1 2 0 0 2 2 2 0 XPA protein C-terminus Macoilin PF09726.4 EGG09465.1 - 5.1 5.2 17.0 5.6 5.1 11.8 1.1 1 0 0 1 1 1 0 Transmembrane protein NUDIX PF00293.23 EGG09466.1 - 7.8e-12 44.9 0.2 1.8e-10 40.5 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain nec1 PF10379.4 EGG09468.1 - 0.021 14.0 0.5 0.025 13.8 0.3 1.1 1 0 0 1 1 1 0 Virulence protein nec1 Grp1_Fun34_YaaH PF01184.14 EGG09470.1 - 1.7e-77 259.4 18.3 2.1e-77 259.1 12.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family YibE_F PF07907.6 EGG09470.1 - 0.0094 15.1 9.1 0.016 14.4 6.3 1.4 1 0 0 1 1 1 1 YibE/F-like protein PAP2 PF01569.16 EGG09471.1 - 1.2e-26 92.8 0.8 1.2e-26 92.8 0.5 1.7 1 1 1 2 2 2 1 PAP2 superfamily DUF912 PF06024.7 EGG09473.1 - 0.085 12.9 0.1 0.93 9.5 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RR_TM4-6 PF06459.7 EGG09474.1 - 2.9 7.7 17.2 0.72 9.6 9.4 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 zf-C2H2_4 PF13894.1 EGG09475.1 - 1.1e-07 31.6 11.5 0.00034 20.7 0.9 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGG09475.1 - 2.2e-06 27.6 12.4 0.00012 22.2 0.5 3.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG09475.1 - 0.24 11.7 0.2 0.24 11.7 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double domain Sec7 PF01369.15 EGG09477.1 - 2.8e-37 128.2 0.7 5.3e-37 127.3 0.5 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EGG09477.1 - 9.6e-30 103.1 0.0 2e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGG09477.1 - 0.00034 20.7 0.0 0.00093 19.3 0.0 1.8 1 0 0 1 1 1 1 PH domain TMV_coat PF00721.16 EGG09482.1 - 0.026 14.4 4.6 0.081 12.8 0.0 2.9 2 1 1 3 3 3 0 Virus coat protein (TMV like) Ras PF00071.17 EGG09483.1 - 2.6e-43 147.1 0.0 3.5e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG09483.1 - 1.8e-17 63.9 0.0 2.4e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG09483.1 - 1.6e-10 40.4 0.0 6e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 EGG09483.1 - 4.6e-06 26.8 0.0 7.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EGG09483.1 - 3.2e-05 23.4 0.0 9.2e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGG09483.1 - 0.00012 21.2 0.0 0.00024 20.3 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EGG09483.1 - 0.00038 20.4 0.1 0.0013 18.8 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 EGG09483.1 - 0.0019 18.1 0.0 0.0032 17.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGG09483.1 - 0.058 13.6 0.4 0.096 12.9 0.0 1.7 2 1 0 2 2 2 0 ABC transporter DUF258 PF03193.11 EGG09483.1 - 0.078 12.1 0.1 0.14 11.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGG09483.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.6 1 1 1 2 2 2 0 Dynamin family AAA_29 PF13555.1 EGG09483.1 - 0.35 10.4 0.0 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain FlaG PF03646.10 EGG09484.1 - 1.8 8.7 8.8 0.17 12.0 1.4 2.1 2 0 0 2 2 2 0 FlaG protein YL1_C PF08265.6 EGG09485.1 - 7.6e-17 60.5 0.1 9.7e-17 60.2 0.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Arm PF00514.18 EGG09486.1 - 0.2 11.5 3.1 10 6.1 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TrbI PF03743.9 EGG09487.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein SLAM PF06214.6 EGG09488.1 - 0.097 12.6 0.1 0.75 9.7 0.0 2.2 1 1 1 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein DUF2833 PF11090.3 EGG09490.1 - 0.12 12.5 0.5 0.28 11.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) UBA_e1_C PF09358.5 EGG09495.1 - 8.7e-45 151.9 0.5 1.7e-44 150.9 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain ThiF PF00899.16 EGG09495.1 - 1.4e-44 151.2 0.3 8.3e-28 96.9 0.0 2.9 3 0 0 3 3 3 2 ThiF family UBACT PF02134.16 EGG09495.1 - 1.7e-41 139.6 2.1 6.4e-26 89.7 0.3 3.6 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGG09495.1 - 1.5e-22 78.6 2.2 3.3e-19 67.9 0.8 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site End_beta_barrel PF12195.3 EGG09495.1 - 0.049 13.3 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase AAA_27 PF13514.1 EGG09497.1 - 2.3e-08 32.2 19.2 3.3e-08 31.7 13.3 1.1 1 0 0 1 1 1 1 AAA domain NUDE_C PF04880.8 EGG09497.1 - 4.5e-06 27.1 26.3 4.5e-06 27.1 18.2 4.2 1 1 2 3 3 2 1 NUDE protein, C-terminal conserved region Prefoldin_2 PF01920.15 EGG09497.1 - 0.0002 21.0 16.6 0.0013 18.5 3.0 4.3 2 1 2 4 4 4 1 Prefoldin subunit IncA PF04156.9 EGG09497.1 - 0.00049 19.7 11.0 0.00049 19.7 7.6 2.7 2 1 1 3 3 3 1 IncA protein DUF904 PF06005.7 EGG09497.1 - 0.00073 19.7 1.0 0.00073 19.7 0.7 4.1 2 1 2 4 4 4 1 Protein of unknown function (DUF904) ATG16 PF08614.6 EGG09497.1 - 0.0017 18.2 29.2 0.0059 16.4 10.8 3.1 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 EGG09497.1 - 0.0039 16.9 23.8 0.027 14.2 1.8 3.4 2 1 2 4 4 3 3 TPR/MLP1/MLP2-like protein DMPK_coil PF08826.5 EGG09497.1 - 0.0091 15.8 0.8 0.0091 15.8 0.5 4.0 1 1 2 3 3 3 1 DMPK coiled coil domain like IFT57 PF10498.4 EGG09497.1 - 0.014 14.1 15.1 0.047 12.4 1.8 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 WEMBL PF05701.6 EGG09497.1 - 0.032 12.7 16.1 0.053 11.9 11.1 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF4200 PF13863.1 EGG09497.1 - 0.04 13.8 19.4 0.084 12.8 5.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TBPIP PF07106.8 EGG09497.1 - 0.069 12.7 14.1 0.31 10.5 6.7 2.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 EGG09497.1 - 0.087 12.3 13.7 0.061 12.8 0.9 3.7 3 1 1 4 4 4 0 Septum formation initiator Filament PF00038.16 EGG09497.1 - 0.17 11.3 26.4 0.084 12.3 9.4 2.8 2 1 1 3 3 3 0 Intermediate filament protein Baculo_PEP_C PF04513.7 EGG09497.1 - 0.18 11.6 5.2 0.23 11.2 1.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PspA_IM30 PF04012.7 EGG09497.1 - 0.58 9.4 15.7 0.34 10.2 7.4 2.3 1 1 1 2 2 2 0 PspA/IM30 family Phage_GP20 PF06810.6 EGG09497.1 - 0.73 9.2 15.5 1.9 7.9 7.0 3.4 2 1 1 3 3 3 0 Phage minor structural protein GP20 TMCO5 PF14992.1 EGG09497.1 - 1.6 7.8 21.5 0.088 11.9 10.8 1.9 2 1 0 2 2 2 0 TMCO5 family AAA_13 PF13166.1 EGG09497.1 - 1.6 7.1 11.8 6.1 5.1 0.3 2.0 1 1 1 2 2 2 0 AAA domain Tweety PF04906.8 EGG09497.1 - 2.7 6.3 3.7 5.9 5.1 0.3 2.2 1 1 0 2 2 2 0 Tweety Syntaxin-6_N PF09177.6 EGG09497.1 - 3.5 8.1 16.8 3.3 8.1 1.7 3.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal WXG100 PF06013.7 EGG09497.1 - 4.2 7.4 6.3 16 5.6 1.9 3.2 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Metal_resist PF13801.1 EGG09497.1 - 5.9 6.8 10.2 16 5.5 0.1 3.5 2 1 0 3 3 3 0 Heavy-metal resistance APG6 PF04111.7 EGG09497.1 - 6 5.8 24.2 1.6 7.7 5.3 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Apc4 PF12896.2 EGG09498.1 - 8.3e-12 44.8 0.2 1.4e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 LRR_4 PF12799.2 EGG09500.1 - 0.14 11.8 21.4 0.52 10.0 0.0 6.5 5 3 3 8 8 8 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.2 EGG09501.1 - 0.018 14.6 12.4 3.9 7.2 0.1 5.9 4 3 2 6 6 6 0 Leucine Rich repeats (2 copies) LSM PF01423.17 EGG09502.1 - 7.3e-11 41.4 0.1 9.6e-11 41.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGG09502.1 - 1e-06 28.5 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3533 PF12051.3 EGG09503.1 - 1.2e-92 310.6 17.6 1.5e-92 310.2 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Aminotran_1_2 PF00155.16 EGG09504.1 - 2e-90 303.4 0.0 2.2e-90 303.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Oxidored_FMN PF00724.15 EGG09504.1 - 0.032 13.2 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family DUF1057 PF06342.7 EGG09506.1 - 0.034 12.9 0.1 0.54 9.0 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF2505 PF10698.4 EGG09507.1 - 0.012 15.1 0.0 0.038 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) Lyase_1 PF00206.15 EGG09508.1 - 1.1e-113 379.5 0.0 1.4e-113 379.1 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EGG09508.1 - 5e-21 74.5 0.1 2.4e-19 69.1 0.0 2.7 2 0 0 2 2 2 1 Fumarase C C-terminus ADSL_C PF10397.4 EGG09508.1 - 0.08 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus Engrail_1_C_sig PF10525.4 EGG09508.1 - 0.47 9.6 2.5 6.9 5.8 0.5 2.4 2 0 0 2 2 2 0 Engrailed homeobox C-terminal signature domain Glyco_transf_8 PF01501.15 EGG09509.1 - 6.6e-30 104.2 0.0 1e-29 103.6 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EGG09509.1 - 0.0083 15.4 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative K_trans PF02705.11 EGG09512.1 - 5.4e-153 510.1 14.5 6.6e-148 493.3 13.1 2.1 2 0 0 2 2 2 2 K+ potassium transporter DUF2414 PF10309.4 EGG09513.1 - 1e-06 28.3 0.0 1.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 EGG09513.1 - 0.0014 18.5 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain Macoilin PF09726.4 EGG09513.1 - 2 6.6 4.3 2.6 6.2 2.9 1.2 1 0 0 1 1 1 0 Transmembrane protein VHS PF00790.14 EGG09514.1 - 4.3e-21 75.0 0.0 1.2e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 VHS domain Cnd1 PF12717.2 EGG09514.1 - 0.0018 18.1 0.1 0.042 13.7 0.0 2.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF2600 PF10776.4 EGG09514.1 - 0.096 11.5 0.0 0.38 9.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2600) WD40 PF00400.27 EGG09515.1 - 1.8e-19 68.7 5.0 0.00054 19.7 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat PASTA PF03793.14 EGG09515.1 - 0.02 14.4 0.2 0.046 13.3 0.1 1.6 1 0 0 1 1 1 0 PASTA domain Alpha_kinase PF02816.13 EGG09516.1 - 3.9e-05 23.4 0.0 4.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family RuvB_N PF05496.7 EGG09516.1 - 0.044 12.8 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Bse634I PF07832.6 EGG09516.1 - 0.054 12.6 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Cfr10I/Bse634I restriction endonuclease DUF3155 PF11352.3 EGG09516.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) DASH_Spc34 PF08657.5 EGG09517.1 - 0.026 14.2 0.8 0.026 14.2 0.5 2.5 3 0 0 3 3 3 0 DASH complex subunit Spc34 gag-asp_proteas PF13975.1 EGG09518.1 - 0.0036 17.0 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EGG09518.1 - 0.014 15.2 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGG09518.1 - 0.026 15.0 0.0 0.074 13.5 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DASH_Dad4 PF08650.5 EGG09518.1 - 0.043 13.7 2.7 0.14 12.0 1.9 1.9 1 0 0 1 1 1 0 DASH complex subunit Dad4 zf-Tim10_DDP PF02953.10 EGG09520.1 - 1.8e-20 72.0 0.7 2.1e-20 71.7 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EGG09520.1 - 0.043 13.2 0.7 0.056 12.9 0.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Alpha-amylase PF00128.19 EGG09521.1 - 0.048 13.0 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain SBBP PF06739.6 EGG09521.1 - 0.095 12.5 0.3 0.27 11.0 0.2 1.8 1 0 0 1 1 1 0 Beta-propeller repeat Ribosomal_L1 PF00687.16 EGG09522.1 - 8.4e-15 54.7 0.1 9.3e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Alpha_GJ PF03229.8 EGG09523.1 - 1.5 9.1 6.1 2 8.7 4.3 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J Myosin_head PF00063.16 EGG09525.1 - 2.6e-14 52.2 0.0 2.6e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) WD40 PF00400.27 EGG09528.1 - 3.5e-31 105.9 13.5 1e-08 34.7 0.0 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EGG09528.1 - 0.0021 17.8 0.8 0.87 9.2 0.0 3.3 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EGG09528.1 - 0.0029 17.1 0.0 0.017 14.6 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 EGG09528.1 - 0.017 15.3 0.0 50 4.3 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain BTV_NS2 PF04514.7 EGG09528.1 - 0.5 9.2 4.6 0.67 8.7 3.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Abhydrolase_1 PF00561.15 EGG09530.1 - 3.2e-16 59.6 0.0 1.8e-14 53.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGG09530.1 - 4.9e-16 59.3 0.0 7.2e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DnaJ PF00226.26 EGG09531.1 - 1.3e-19 69.6 0.4 4.1e-19 68.0 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain MU117 PF15474.1 EGG09532.1 - 0.00019 21.8 0.4 0.00029 21.2 0.3 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene family ILVD_EDD PF00920.16 EGG09532.1 - 0.15 10.4 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Dehydratase family SRP-alpha_N PF04086.8 EGG09533.1 - 0.25 10.6 11.3 0.34 10.2 7.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Selenoprotein_S PF06936.6 EGG09533.1 - 2.9 7.4 13.9 4.7 6.7 9.6 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) Toxin_37 PF11415.3 EGG09537.1 - 0.37 10.4 5.0 6 6.5 0.1 3.2 3 0 0 3 3 3 0 Antifungal peptide termicin MIP PF00230.15 EGG09538.1 - 7.4e-22 77.9 15.4 1e-21 77.4 10.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein D123 PF07065.9 EGG09540.1 - 2.3e-72 243.6 0.2 8.7e-72 241.7 0.1 1.8 1 1 0 1 1 1 1 D123 FH2 PF02181.18 EGG09541.1 - 9.2e-60 202.4 18.3 3.4e-59 200.5 2.6 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain Drf_GBD PF06371.8 EGG09541.1 - 1e-40 139.0 0.0 1e-40 139.0 0.0 2.7 3 1 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EGG09541.1 - 2.6e-36 124.8 0.1 2.6e-36 124.8 0.1 3.2 4 0 0 4 4 4 1 Diaphanous FH3 Domain Prenyltrans PF00432.16 EGG09542.1 - 2.2e-29 100.6 11.6 3.1e-10 39.4 0.1 6.2 6 1 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EGG09542.1 - 1.2e-27 96.0 1.4 7.9e-13 48.3 0.1 5.9 3 3 3 6 6 6 5 Prenyltransferase-like Prenyltrans_2 PF13249.1 EGG09542.1 - 3.3e-24 85.4 1.2 2.9e-14 53.4 0.1 5.3 2 2 3 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 EGG09542.1 - 8.6e-08 31.6 2.8 1.2 8.2 0.0 5.8 4 2 2 6 6 6 4 Pectic acid lyase G-patch PF01585.18 EGG09543.1 - 8.3e-13 47.9 3.4 1.6e-12 46.9 2.3 1.5 1 0 0 1 1 1 1 G-patch domain RRM_6 PF14259.1 EGG09543.1 - 2.6e-12 46.5 0.0 2e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGG09543.1 - 4.1e-12 45.5 0.0 2.7e-07 30.0 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EGG09543.1 - 1.2e-06 28.3 0.1 1.2e-06 28.3 0.1 2.1 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_5 PF13893.1 EGG09543.1 - 0.00084 19.1 0.0 0.049 13.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2547 PF10818.3 EGG09545.1 - 0.015 15.8 0.5 0.031 14.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) DUF605 PF04652.11 EGG09547.1 - 0.22 10.8 10.9 0.29 10.4 7.5 1.3 1 0 0 1 1 1 0 Vta1 like OPT PF03169.10 EGG09549.1 - 4.8e-169 563.7 39.4 5.5e-169 563.5 27.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein LIN37 PF15306.1 EGG09551.1 - 0.021 14.8 2.5 0.027 14.4 1.7 1.2 1 0 0 1 1 1 0 LIN37 D123 PF07065.9 EGG09551.1 - 0.032 13.2 1.7 0.04 12.9 1.2 1.1 1 0 0 1 1 1 0 D123 SURF2 PF05477.6 EGG09551.1 - 0.068 12.2 6.2 0.085 11.9 4.3 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Parathyroid PF01279.12 EGG09551.1 - 0.11 13.1 2.0 0.14 12.7 1.4 1.2 1 0 0 1 1 1 0 Parathyroid hormone family Pox_Ag35 PF03286.9 EGG09551.1 - 0.15 11.5 5.1 0.19 11.2 3.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein AAR2 PF05282.6 EGG09551.1 - 0.15 10.9 3.0 0.18 10.6 2.0 1.1 1 0 0 1 1 1 0 AAR2 protein NAM-associated PF14303.1 EGG09551.1 - 0.18 12.1 10.9 0.56 10.5 7.4 1.7 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF3530 PF12048.3 EGG09551.1 - 0.18 10.7 2.6 0.19 10.6 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Adeno_terminal PF02459.10 EGG09551.1 - 0.49 8.4 5.5 0.61 8.1 3.8 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein RP-C_C PF11800.3 EGG09551.1 - 0.52 9.9 2.8 0.61 9.7 1.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Ycf1 PF05758.7 EGG09551.1 - 0.55 7.8 6.2 0.63 7.6 4.3 1.0 1 0 0 1 1 1 0 Ycf1 Na_trans_assoc PF06512.8 EGG09551.1 - 0.55 10.1 8.6 0.63 9.9 6.0 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated RRN3 PF05327.6 EGG09551.1 - 0.67 8.0 3.9 0.74 7.8 2.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FlaG PF03646.10 EGG09551.1 - 0.81 9.8 5.8 1.1 9.4 4.0 1.2 1 0 0 1 1 1 0 FlaG protein Uds1 PF15456.1 EGG09551.1 - 0.95 9.4 7.5 1.6 8.6 5.2 1.5 1 1 0 1 1 1 0 Up-regulated During Septation CDC45 PF02724.9 EGG09551.1 - 1.1 7.1 6.3 1.2 7.0 4.3 1.0 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.11 EGG09552.1 - 7.4e-33 113.7 30.2 6.3e-26 90.9 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG09552.1 - 1.7e-25 89.5 15.1 2.2e-25 89.1 10.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter FAR1 PF03101.10 EGG09553.1 - 0.023 15.2 0.1 0.042 14.3 0.1 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain IcmF-related PF06761.7 EGG09554.1 - 0.044 13.0 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing Alpha_kinase PF02816.13 EGG09556.1 - 0.0033 17.1 0.0 0.006 16.2 0.0 1.5 1 0 0 1 1 1 1 Alpha-kinase family Daxx PF03344.10 EGG09557.1 - 0.55 8.6 9.7 0.63 8.4 6.7 1.0 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EGG09557.1 - 1.1 7.0 8.9 1.1 7.0 6.1 1.0 1 0 0 1 1 1 0 Nop14-like family Pheromone PF08015.6 EGG09559.1 - 9 7.2 10.3 1.6 9.6 1.8 2.8 1 1 1 2 2 2 0 Fungal mating-type pheromone Prefoldin_2 PF01920.15 EGG09561.1 - 6.1e-20 70.9 1.6 6.8e-20 70.8 1.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF387 PF04079.11 EGG09561.1 - 0.0015 17.9 0.3 0.0062 15.9 0.0 1.8 2 0 0 2 2 2 1 Putative transcriptional regulators (Ypuh-like) V-ATPase_C PF03223.10 EGG09561.1 - 0.0046 15.9 0.7 0.12 11.2 0.1 2.0 2 0 0 2 2 2 1 V-ATPase subunit C TPR_MLP1_2 PF07926.7 EGG09561.1 - 0.005 16.5 1.9 1.1 8.9 0.1 2.0 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.17 EGG09561.1 - 0.0074 16.2 0.3 0.31 11.0 0.0 2.2 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain GAS PF13851.1 EGG09561.1 - 0.0094 15.1 1.0 0.92 8.6 0.0 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 EGG09561.1 - 0.025 14.4 2.7 0.53 10.1 0.1 2.1 2 0 0 2 2 2 0 Tropomyosin like TBPIP PF07106.8 EGG09561.1 - 0.028 13.9 1.2 0.66 9.4 0.0 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ROS_MUCR PF05443.6 EGG09561.1 - 0.033 13.9 0.1 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein TMF_DNA_bd PF12329.3 EGG09561.1 - 0.04 13.7 2.6 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 EGG09561.1 - 0.05 12.0 0.6 0.45 8.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain SCP-1 PF05483.7 EGG09561.1 - 0.051 11.3 0.4 0.062 11.0 0.3 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Lectin_N PF03954.9 EGG09561.1 - 0.053 12.9 0.4 0.072 12.4 0.3 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Med4 PF10018.4 EGG09561.1 - 0.061 12.7 2.4 0.25 10.6 1.7 1.9 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CTK3 PF12243.3 EGG09561.1 - 0.062 12.9 0.1 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 K-box PF01486.12 EGG09561.1 - 0.077 12.8 2.1 2.5 7.9 0.3 2.1 2 0 0 2 2 2 0 K-box region TrmB PF01978.14 EGG09561.1 - 0.088 12.5 0.4 1.9 8.2 0.0 2.1 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sec20 PF03908.8 EGG09561.1 - 0.094 12.4 0.1 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Sec20 Cortex-I_coil PF09304.5 EGG09561.1 - 0.11 12.4 1.3 2.6 8.1 0.1 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF3287 PF11690.3 EGG09561.1 - 0.15 12.1 0.5 14 5.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Spc42p PF11544.3 EGG09561.1 - 0.15 11.9 0.9 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Spindle pole body component Spc42p Herpes_pp38 PF04846.8 EGG09561.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein CENP-F_leu_zip PF10473.4 EGG09561.1 - 0.17 11.7 1.8 1.5 8.6 0.1 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.7 EGG09561.1 - 0.2 11.4 2.4 2.8 7.6 0.2 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Occludin_ELL PF07303.8 EGG09561.1 - 0.23 12.1 2.0 4.8 7.9 0.1 2.1 2 0 0 2 2 2 0 Occludin homology domain DivIVA PF05103.8 EGG09561.1 - 0.57 10.2 2.9 1.2 9.2 0.3 2.0 2 0 0 2 2 2 0 DivIVA protein Snf7 PF03357.16 EGG09561.1 - 0.57 9.5 3.4 1.1 8.5 1.0 1.9 1 1 1 2 2 2 0 Snf7 DUF904 PF06005.7 EGG09561.1 - 0.84 9.9 4.4 5.3 7.3 3.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) zf-RING_4 PF14570.1 EGG09562.1 - 0.32 10.6 7.2 0.33 10.5 2.4 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Peptidase_C48 PF02902.14 EGG09564.1 - 5.2e-34 117.7 2.3 1.2e-33 116.6 1.6 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.8 EGG09564.1 - 0.014 13.9 0.1 0.027 12.9 0.0 1.4 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase Nab2 PF11517.3 EGG09566.1 - 0.047 13.7 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.1 EGG09566.1 - 0.52 10.3 29.4 0.71 9.9 4.5 4.2 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type DUF935 PF06074.7 EGG09566.1 - 2.1 6.9 4.1 2.8 6.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF935) Methyltransf_16 PF10294.4 EGG09567.1 - 6.4e-13 48.5 0.0 1.5e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Chromo PF00385.19 EGG09567.1 - 0.025 14.2 0.4 0.6 9.8 0.1 2.6 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Methyltransf_18 PF12847.2 EGG09567.1 - 0.14 12.7 0.0 0.36 11.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain S1_2 PF13509.1 EGG09568.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 S1 domain AAA PF00004.24 EGG09569.1 - 1.4e-40 138.5 0.0 2.4e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EGG09569.1 - 1.2e-23 82.7 0.0 3.5e-23 81.2 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EGG09569.1 - 4e-19 68.2 2.7 4e-19 68.2 1.9 2.3 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EGG09569.1 - 1.7e-05 25.6 0.3 0.00011 22.9 0.0 2.5 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.9 EGG09569.1 - 2.7e-05 23.9 0.0 7.9e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGG09569.1 - 2.9e-05 24.2 0.1 0.0026 17.9 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGG09569.1 - 3e-05 23.9 0.0 8.6e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGG09569.1 - 3.8e-05 23.1 0.0 7.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EGG09569.1 - 4.8e-05 23.4 1.0 0.011 15.8 0.0 3.7 4 0 0 4 4 4 1 RNA helicase AAA_16 PF13191.1 EGG09569.1 - 6.5e-05 22.9 0.0 0.0016 18.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EGG09569.1 - 8.3e-05 21.7 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EGG09569.1 - 0.00011 21.0 0.0 0.00019 20.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EGG09569.1 - 0.00023 20.1 0.0 0.0036 16.2 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EGG09569.1 - 0.00043 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGG09569.1 - 0.00048 19.5 0.1 0.2 11.0 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EGG09569.1 - 0.00077 19.4 0.0 0.022 14.6 0.0 2.5 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EGG09569.1 - 0.0053 17.0 0.3 0.031 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EGG09569.1 - 0.0093 15.6 0.0 0.24 11.0 0.0 2.5 1 1 1 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 EGG09569.1 - 0.012 15.3 0.8 0.29 10.8 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase AAA_24 PF13479.1 EGG09569.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGG09569.1 - 0.023 14.4 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EGG09569.1 - 0.026 13.6 0.0 0.067 12.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EGG09569.1 - 0.028 13.5 0.1 0.3 10.1 0.0 2.3 1 1 1 2 2 2 0 Zeta toxin ResIII PF04851.10 EGG09569.1 - 0.033 14.0 0.4 0.096 12.5 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 EGG09569.1 - 0.052 12.7 0.1 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EGG09569.1 - 0.057 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_21 PF13304.1 EGG09569.1 - 0.067 13.1 1.2 3.5 7.5 0.0 3.0 2 1 1 3 3 3 0 AAA domain Guanylate_kin PF00625.16 EGG09569.1 - 0.077 12.4 0.2 0.33 10.3 0.0 2.2 2 0 0 2 2 1 0 Guanylate kinase KaiC PF06745.8 EGG09569.1 - 0.082 12.0 0.0 5.4 6.0 0.0 2.3 1 1 1 2 2 2 0 KaiC DUF2634 PF10934.3 EGG09569.1 - 0.084 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) Torsin PF06309.6 EGG09569.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin CPT PF07931.7 EGG09569.1 - 0.12 11.9 0.0 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Asp PF00026.18 EGG09571.1 - 1.8e-54 185.1 6.4 2.2e-54 184.8 4.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG09571.1 - 2.1e-07 31.0 0.8 5.7e-06 26.3 0.6 3.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal ChiC PF06483.6 EGG09571.1 - 0.0044 16.7 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 Chitinase C DUF718 PF05336.8 EGG09574.1 - 0.0046 16.7 1.3 0.0046 16.7 0.9 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF718) DUF904 PF06005.7 EGG09574.1 - 0.27 11.5 3.5 5.8 7.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF904) RRM_1 PF00076.17 EGG09575.1 - 1.5e-07 30.9 0.0 2.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG09575.1 - 7.8e-06 25.7 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG09575.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2OG-FeII_Oxy_2 PF13532.1 EGG09579.1 - 3.8e-12 46.4 0.0 4.8e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGG09579.1 - 0.01 16.0 0.0 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DSPc PF00782.15 EGG09583.1 - 9.6e-29 99.6 0.0 1.2e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGG09583.1 - 0.005 16.2 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Vps5 PF09325.5 EGG09584.1 - 1.6e-10 40.6 3.6 3e-10 39.7 2.5 1.5 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EGG09584.1 - 1.6e-08 34.2 0.1 3.9e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 PX domain Cation_efflux PF01545.16 EGG09587.1 - 4.4e-29 101.4 1.1 5.5e-29 101.1 0.8 1.1 1 0 0 1 1 1 1 Cation efflux family Lipase_3 PF01764.20 EGG09588.1 - 2.6e-15 56.2 0.0 6.5e-15 54.9 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 EGG09588.1 - 0.019 14.7 0.1 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 EGG09588.1 - 0.038 13.7 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3173 PF11372.3 EGG09588.1 - 0.086 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) DdrB PF12747.2 EGG09589.1 - 0.099 12.3 0.2 0.17 11.5 0.1 1.6 2 0 0 2 2 2 0 DdrB-like protein YchF-GTPase_C PF06071.8 EGG09589.1 - 0.1 12.3 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF933) CAF-1_p150 PF11600.3 EGG09590.1 - 1.2 8.4 13.5 1.7 7.9 9.4 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 EGG09590.1 - 9.4 4.3 17.4 10 4.2 12.0 1.0 1 0 0 1 1 1 0 Transmembrane protein UPF0121 PF03661.8 EGG09591.1 - 2.1e-19 69.6 4.2 2.5e-19 69.4 2.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF788 PF05620.6 EGG09591.1 - 1.2 9.0 4.9 1.5 8.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF788) CPSF73-100_C PF11718.3 EGG09593.1 - 0.019 14.3 1.6 0.033 13.5 1.1 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF1180 PF06679.7 EGG09593.1 - 2.5 7.9 5.2 5.6 6.8 3.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) MCM PF00493.18 EGG09595.1 - 5.6e-136 452.6 0.1 9.3e-136 451.9 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGG09595.1 - 7e-19 68.4 0.1 2.3e-18 66.8 0.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGG09595.1 - 1.5e-08 34.0 0.0 3.6e-07 29.5 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGG09595.1 - 0.0015 18.1 0.0 0.004 16.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGG09595.1 - 0.0032 16.9 0.0 0.0068 15.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EGG09595.1 - 0.0074 16.0 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2151 PF10221.4 EGG09595.1 - 0.0095 14.1 1.8 0.021 12.9 0.3 2.0 2 0 0 2 2 2 1 Cell cycle and development regulator SapB_1 PF05184.10 EGG09595.1 - 0.18 11.6 5.2 0.41 10.5 0.4 3.3 3 0 0 3 3 3 0 Saposin-like type B, region 1 zf-ribbon_3 PF13248.1 EGG09596.1 - 0.071 12.3 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain F-box-like PF12937.2 EGG09599.1 - 0.0013 18.4 0.0 0.0047 16.6 0.0 2.0 1 1 0 1 1 1 1 F-box-like DUF4259 PF14078.1 EGG09600.1 - 0.54 10.7 4.6 2.4 8.6 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) LRR_4 PF12799.2 EGG09601.1 - 0.0015 18.1 3.6 0.45 10.1 0.1 3.1 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EGG09601.1 - 0.077 13.1 0.1 10 6.5 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat TPR_12 PF13424.1 EGG09603.1 - 7.5e-14 51.4 0.7 2.4e-09 37.0 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-MYND PF01753.13 EGG09603.1 - 1.7e-09 37.4 15.7 2.7e-09 36.7 10.9 1.4 1 0 0 1 1 1 1 MYND finger TPR_2 PF07719.12 EGG09603.1 - 1e-08 34.4 2.4 0.16 11.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGG09603.1 - 2.9e-07 30.9 6.8 0.00051 20.6 1.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGG09603.1 - 1e-06 28.2 0.1 0.00023 20.7 0.0 2.5 2 0 0 2 2 2 1 TPR repeat Apc3 PF12895.2 EGG09603.1 - 1.4e-06 28.3 1.5 0.0021 18.1 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EGG09603.1 - 1.6e-06 27.4 1.2 0.12 11.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EGG09603.1 - 3.2e-06 26.8 2.0 0.029 14.3 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGG09603.1 - 8.2e-06 26.0 2.4 4.4e-05 23.7 0.8 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGG09603.1 - 3.7e-05 23.9 1.4 0.088 13.4 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EGG09603.1 - 3.9e-05 23.6 0.5 0.018 15.4 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG09603.1 - 9.2e-05 21.9 1.1 0.26 11.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGG09603.1 - 0.0001 21.8 1.2 1.6 8.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGG09603.1 - 0.00079 19.4 0.6 6.8 7.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGG09603.1 - 0.049 14.0 3.1 23 5.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 EGG09603.1 - 0.063 12.6 0.1 0.23 10.8 0.0 2.0 1 1 1 2 2 2 0 26S proteasome subunit RPN7 T2SF PF00482.18 EGG09603.1 - 0.19 11.6 0.2 0.19 11.6 0.1 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F TPR_12 PF13424.1 EGG09604.1 - 3.8e-10 39.5 1.8 2.4e-05 24.2 0.7 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-MYND PF01753.13 EGG09604.1 - 1.4e-08 34.4 16.7 2.7e-08 33.5 11.6 1.5 1 0 0 1 1 1 1 MYND finger TPR_8 PF13181.1 EGG09604.1 - 4.5e-07 29.1 3.0 0.026 14.2 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGG09604.1 - 2.3e-06 27.0 2.8 0.041 13.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGG09604.1 - 3.1e-06 26.9 0.3 0.00065 19.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGG09604.1 - 5.1e-06 25.8 2.9 0.071 12.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGG09604.1 - 8.3e-05 22.1 0.5 0.00056 19.5 0.0 2.2 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.1 EGG09604.1 - 0.00033 20.6 0.4 2.1 8.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG09604.1 - 0.00065 19.3 0.2 0.27 11.1 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 EGG09604.1 - 0.0017 17.7 0.4 0.13 11.6 0.1 2.3 1 1 1 2 2 2 1 26S proteasome subunit RPN7 TPR_16 PF13432.1 EGG09604.1 - 0.0026 18.3 0.3 0.11 13.1 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGG09604.1 - 0.0027 18.2 0.4 1.5 9.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGG09604.1 - 0.007 16.6 0.4 0.076 13.3 0.1 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGG09604.1 - 0.011 16.0 0.1 3 8.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Septin PF00735.13 EGG09605.1 - 1e-117 392.1 0.2 1e-117 392.1 0.1 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EGG09605.1 - 5.6e-08 32.7 0.0 1.4e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGG09605.1 - 2.7e-05 23.6 1.4 0.00024 20.5 0.0 2.8 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGG09605.1 - 3.6e-05 22.9 0.0 0.0001 21.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGG09605.1 - 0.00029 20.6 1.1 0.0055 16.5 0.0 3.0 2 1 0 2 2 2 1 Dynamin family ABC_tran PF00005.22 EGG09605.1 - 0.00035 20.8 4.3 0.013 15.8 0.0 2.8 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 EGG09605.1 - 0.0013 18.8 0.0 0.0082 16.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain Ras PF00071.17 EGG09605.1 - 0.0039 16.5 0.1 0.025 13.9 0.0 2.3 2 0 0 2 2 2 1 Ras family AAA_10 PF12846.2 EGG09605.1 - 0.004 16.6 0.0 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain Miro PF08477.8 EGG09605.1 - 0.004 17.6 0.1 0.023 15.1 0.0 2.4 3 1 0 3 3 3 1 Miro-like protein AAA_16 PF13191.1 EGG09605.1 - 0.0041 17.1 0.2 0.024 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.11 EGG09605.1 - 0.005 15.9 0.2 0.021 13.9 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_29 PF13555.1 EGG09605.1 - 0.0093 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 EGG09605.1 - 0.016 14.9 0.2 0.048 13.3 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Strep_SA_rep PF06696.6 EGG09605.1 - 0.016 14.9 1.9 0.11 12.2 0.1 2.5 1 1 1 2 2 2 0 Streptococcal surface antigen repeat Exonuc_VII_L PF02601.10 EGG09605.1 - 0.04 13.1 5.2 0.13 11.4 3.6 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit AbiH PF14253.1 EGG09605.1 - 0.043 13.4 2.1 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH AAA_24 PF13479.1 EGG09605.1 - 0.047 13.2 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EGG09605.1 - 0.051 13.0 0.1 3 7.3 0.0 3.3 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EGG09605.1 - 0.12 12.5 0.3 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase IncA PF04156.9 EGG09605.1 - 2.4 7.6 6.7 4.1 6.9 4.6 1.4 1 0 0 1 1 1 0 IncA protein MBOAT_2 PF13813.1 EGG09607.1 - 1.3e-10 41.2 2.3 3.1e-10 39.9 1.6 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.1 EGG09610.1 - 7.4e-10 38.7 2.3 1.4e-09 37.9 1.6 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Ras PF00071.17 EGG09611.1 - 6e-64 214.2 0.4 7.1e-64 214.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG09611.1 - 5.1e-22 78.6 0.1 7.2e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG09611.1 - 2.4e-13 49.7 0.1 3.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGG09611.1 - 8.8e-08 32.1 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGG09611.1 - 2.9e-05 23.3 0.4 5.1e-05 22.5 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGG09611.1 - 5.3e-05 22.7 0.1 0.00015 21.2 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 EGG09611.1 - 9.5e-05 21.6 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGG09611.1 - 0.00019 21.6 0.1 0.00057 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGG09611.1 - 0.0024 17.0 0.1 0.0074 15.4 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EGG09611.1 - 0.0046 16.8 0.1 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EGG09611.1 - 0.0067 15.6 0.0 0.0099 15.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EGG09611.1 - 0.016 15.5 0.1 0.025 14.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EGG09611.1 - 0.041 13.8 0.3 0.087 12.8 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF1128 PF06569.6 EGG09611.1 - 0.046 13.4 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) AAA_5 PF07728.9 EGG09611.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EGG09611.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GCM PF03615.10 EGG09612.1 - 0.046 13.3 2.4 0.15 11.6 1.7 1.8 1 1 0 1 1 1 0 GCM motif protein Ribosomal_S13 PF00416.17 EGG09614.1 - 1.1e-19 70.8 0.0 1.9e-19 70.0 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Pput2613-deam PF14427.1 EGG09614.1 - 0.037 13.7 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Pput_2613-like deaminase LRR_9 PF14580.1 EGG09615.1 - 1.1e-37 129.3 0.2 2e-37 128.4 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EGG09615.1 - 1.8e-20 72.1 29.5 4.8e-09 35.6 4.0 4.1 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG09615.1 - 7.2e-10 38.4 11.5 7.2e-08 32.0 4.5 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 EGG09615.1 - 4.9e-08 31.9 4.6 0.36 11.2 0.3 4.6 4 0 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 EGG09615.1 - 3.2e-07 29.4 12.4 0.011 15.6 0.4 5.2 4 1 1 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 EGG09615.1 - 5.3e-05 22.8 11.3 0.37 11.0 0.3 4.3 4 0 0 4 4 4 3 Leucine Rich repeat NESP55 PF06390.7 EGG09615.1 - 0.11 11.8 4.8 0.16 11.2 3.3 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) TT_ORF2 PF02957.10 EGG09616.1 - 0.0037 17.9 0.9 0.012 16.3 0.6 1.8 1 0 0 1 1 1 1 TT viral ORF2 DUF4266 PF14086.1 EGG09616.1 - 0.19 12.2 0.5 2.5 8.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) Glyco_hydro_26 PF02156.10 EGG09617.1 - 6.5e-06 25.8 0.3 8.6e-06 25.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Glyco_hydro_26 PF02156.10 EGG09618.1 - 0.00027 20.5 1.4 0.00039 19.9 0.5 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 26 SNF2_N PF00176.18 EGG09619.1 - 7.6e-53 179.2 0.1 1.2e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGG09619.1 - 7e-12 45.0 0.0 2.1e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-PHD-like PF15446.1 EGG09619.1 - 5.7e-07 28.9 8.9 4.7e-05 22.7 2.7 3.0 2 1 0 2 2 2 2 PHD/FYVE-zinc-finger like domain Chromo PF00385.19 EGG09619.1 - 6.5e-06 25.7 2.7 0.0083 15.7 0.0 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EGG09619.1 - 0.0012 18.5 2.5 0.0012 18.5 1.7 3.2 3 0 0 3 3 3 2 PHD-finger DUF836 PF05768.9 EGG09620.1 - 1.2e-09 38.2 0.1 1.5e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 EGG09620.1 - 0.00015 21.9 0.0 0.00017 21.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Snf7 PF03357.16 EGG09622.1 - 5e-20 71.5 3.6 5e-20 71.5 2.5 1.3 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.9 EGG09622.1 - 0.014 14.7 1.0 0.025 13.9 0.7 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway polyprenyl_synt PF00348.12 EGG09623.1 - 9.4e-52 175.4 0.0 1.1e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SR-25 PF10500.4 EGG09623.1 - 5.6 6.3 10.1 8.6 5.7 7.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4500 PF14937.1 EGG09624.1 - 0.0045 16.7 1.1 1.4 8.7 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4500) FUN14 PF04930.10 EGG09624.1 - 0.35 11.1 3.5 3 8.1 1.5 2.7 1 1 1 2 2 2 0 FUN14 family Bax1-I PF01027.15 EGG09624.1 - 4.8 6.7 17.9 0.23 11.0 7.6 1.9 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Caveolin PF01146.12 EGG09624.1 - 6.8 6.2 9.9 1.1 8.8 2.9 2.2 2 0 0 2 2 2 0 Caveolin Herpes_gE PF02480.11 EGG09625.1 - 0.12 10.6 0.0 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Mitofilin PF09731.4 EGG09627.1 - 0.22 10.1 23.9 0.36 9.4 16.5 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein WD40 PF00400.27 EGG09628.1 - 4.4e-25 86.5 10.2 1.2e-09 37.6 0.2 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Lar_restr_allev PF14354.1 EGG09628.1 - 4.9 7.5 0.0 4.9 7.5 0.0 3.1 3 1 0 3 3 3 0 Restriction alleviation protein Lar Cas_NE0113 PF09623.5 EGG09631.1 - 0.14 11.6 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) DUF342 PF03961.8 EGG09633.1 - 0.0013 17.1 2.5 0.0018 16.7 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Cep57_CLD_2 PF14197.1 EGG09633.1 - 0.0076 16.1 3.5 0.26 11.2 0.4 3.0 1 1 1 2 2 2 2 Centrosome localisation domain of PPC89 Gon7 PF08738.5 EGG09633.1 - 0.043 13.7 0.3 0.076 13.0 0.2 1.3 1 0 0 1 1 1 0 Gon7 family TMF_DNA_bd PF12329.3 EGG09633.1 - 1.1 9.0 5.9 0.53 10.1 0.6 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 EGG09633.1 - 1.2 8.9 5.9 3 7.6 4.1 1.7 1 1 0 1 1 1 0 Tropomyosin like IncA PF04156.9 EGG09633.1 - 1.4 8.4 6.9 8.9 5.8 3.3 2.2 1 1 1 2 2 2 0 IncA protein Macoilin PF09726.4 EGG09635.1 - 1.2 7.3 10.1 1.8 6.7 7.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Pr_beta_C PF12465.3 EGG09636.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Proteasome beta subunits C terminal Topo_C_assoc PF14370.1 EGG09638.1 - 0.013 15.1 0.5 0.027 14.1 0.3 1.4 1 0 0 1 1 1 0 C-terminal topoisomerase domain P22_AR_N PF10547.4 EGG09639.1 - 0.12 12.2 1.0 0.38 10.5 0.2 2.2 3 0 0 3 3 3 0 P22_AR N-terminal domain Pkinase PF00069.20 EGG09641.1 - 1.4e-63 214.4 0.0 2.2e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG09641.1 - 5.2e-28 97.8 0.0 9.3e-27 93.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG09641.1 - 0.00023 20.2 0.0 0.013 14.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EGG09641.1 - 0.034 13.1 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C2 PF00168.25 EGG09642.1 - 1e-11 44.4 0.0 3.9e-10 39.4 0.0 2.5 1 1 1 2 2 2 1 C2 domain NT-C2 PF10358.4 EGG09642.1 - 0.022 14.2 0.0 0.054 12.9 0.0 1.6 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins C2 PF00168.25 EGG09643.1 - 2.5e-09 36.8 0.0 1.1e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 C2 domain DUF572 PF04502.8 EGG09645.1 - 2.1e-68 230.9 6.3 2.2e-68 230.8 4.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 EGG09645.1 - 0.024 14.5 0.7 0.34 10.7 0.0 2.0 1 1 1 2 2 2 0 Benyvirus 14KDa protein DUF3797 PF12677.2 EGG09645.1 - 0.026 14.1 0.2 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) DUF3133 PF11331.3 EGG09645.1 - 0.096 12.2 0.3 2.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) Zn_Tnp_IS1 PF03811.8 EGG09645.1 - 0.14 11.6 0.8 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 InsA N-terminal domain zf-DNA_Pol PF08996.5 EGG09645.1 - 0.17 11.2 1.8 6.1 6.1 0.1 2.2 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zinc_ribbon_5 PF13719.1 EGG09645.1 - 0.22 11.1 2.8 2.4 7.8 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGG09645.1 - 0.34 10.6 3.1 4.1 7.1 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EGG09645.1 - 0.57 9.5 2.8 0.62 9.4 0.3 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding DNA_pol_viral_N PF00242.12 EGG09646.1 - 1.2 8.0 9.4 1.7 7.6 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain UBN2 PF14223.1 EGG09647.1 - 7.8e-06 25.6 0.1 1.2e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG09647.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DOG1 PF14144.1 EGG09647.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Seed dormancy control Adap_comp_sub PF00928.16 EGG09649.1 - 1.1e-36 126.3 0.0 1.2e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family EF_assoc_1 PF08355.7 EGG09650.1 - 0.038 13.2 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 EF hand associated YagB_YeeU_YfjZ PF06154.6 EGG09651.1 - 0.072 13.3 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 YagB/YeeU/YfjZ family TSKS PF15358.1 EGG09652.1 - 0.026 12.6 2.9 0.017 13.2 0.6 1.7 2 1 0 2 2 2 0 Testis-specific serine kinase substrate Pellino PF04710.9 EGG09652.1 - 0.04 12.5 0.1 0.04 12.5 0.1 1.4 2 0 0 2 2 2 0 Pellino Bud13 PF09736.4 EGG09653.1 - 2.3e-05 24.6 0.0 2.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex Hep_59 PF07052.6 EGG09654.1 - 9.5e-28 96.6 0.6 9.5e-28 96.6 0.4 3.7 3 2 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Fer4 PF00037.22 EGG09655.1 - 2.5e-14 52.1 15.8 1.5e-08 33.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EGG09655.1 - 2.4e-12 47.0 9.3 3.8e-12 46.4 6.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EGG09655.1 - 9.7e-11 42.2 6.2 4.8e-05 24.0 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 EGG09655.1 - 6.4e-10 38.9 30.2 5.3e-06 26.3 8.2 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGG09655.1 - 7.3e-10 38.9 9.9 1.7e-09 37.8 6.9 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGG09655.1 - 9.5e-10 38.1 21.5 9.6e-08 31.7 8.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 EGG09655.1 - 3.1e-09 36.5 21.5 1.5e-06 27.9 8.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGG09655.1 - 2.4e-08 33.4 14.0 0.00014 21.5 1.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EGG09655.1 - 2.7e-08 33.3 16.2 0.00048 19.8 2.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EGG09655.1 - 4.3e-07 29.7 11.3 0.00019 21.5 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EGG09655.1 - 5e-07 29.9 29.5 0.00013 22.2 7.4 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGG09655.1 - 7e-06 26.3 10.1 0.0093 16.3 0.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EGG09655.1 - 0.00019 21.7 11.9 0.059 13.7 0.5 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 EGG09655.1 - 0.0016 18.4 3.8 0.019 15.0 0.1 2.1 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_15 PF13459.1 EGG09655.1 - 0.002 18.6 12.4 0.11 13.1 0.9 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EGG09655.1 - 0.013 16.0 18.1 0.041 14.4 3.2 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_11 PF13247.1 EGG09655.1 - 0.036 13.9 3.3 0.06 13.2 2.3 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Chorismate_bind PF00425.13 EGG09656.1 - 5.4e-76 255.3 0.0 8.5e-76 254.6 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EGG09656.1 - 3e-28 98.5 0.0 1.2e-27 96.6 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EGG09656.1 - 2.6e-13 50.1 0.0 6.1e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EGG09656.1 - 1.9e-10 40.5 0.0 3.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 Chon_Sulph_att PF06566.6 EGG09657.1 - 3.3 7.2 9.8 0.23 11.0 3.1 1.7 2 0 0 2 2 2 0 Chondroitin sulphate attachment domain PKI PF02827.11 EGG09660.1 - 0.025 14.6 1.7 0.025 14.6 1.2 2.3 2 1 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Daxx PF03344.10 EGG09660.1 - 0.8 8.1 10.7 0.85 8.0 7.4 1.1 1 0 0 1 1 1 0 Daxx Family SRP-alpha_N PF04086.8 EGG09660.1 - 0.92 8.8 11.0 1.2 8.4 7.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Bd3614-deam PF14439.1 EGG09660.1 - 1.3 8.8 4.3 1.6 8.6 2.6 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase FCP1_C PF09309.5 EGG09660.1 - 1.3 8.2 11.5 1.8 7.7 8.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal DUF2201_N PF13203.1 EGG09660.1 - 1.5 7.9 8.5 1.9 7.6 5.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Nucleo_P87 PF07267.6 EGG09660.1 - 7.1 5.1 9.0 8.8 4.8 6.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2146 PF10220.4 EGG09660.1 - 9.3 4.0 8.3 11 3.8 5.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) 2Fe-2S_thioredx PF01257.14 EGG09661.1 - 1e-58 197.0 0.1 1.3e-58 196.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.6 EGG09661.1 - 0.04 14.1 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) Alpha_kinase PF02816.13 EGG09666.1 - 0.005 16.5 0.0 0.0077 15.9 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Rad4 PF03835.10 EGG09667.1 - 4.8 6.5 7.6 15 4.9 0.5 3.2 3 0 0 3 3 3 0 Rad4 transglutaminase-like domain VCBS PF13517.1 EGG09668.1 - 3.5e-22 78.5 10.8 8.2e-07 29.3 0.0 5.0 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EGG09668.1 - 1.7e-13 49.7 9.5 0.0017 18.0 0.0 6.2 6 0 0 6 6 6 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 EGG09668.1 - 4.5e-07 29.4 4.3 0.76 9.1 0.0 5.2 5 1 1 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region Sex_peptide PF08138.6 EGG09668.1 - 0.14 12.0 0.0 0.44 10.4 0.0 1.8 1 0 0 1 1 1 0 Sex peptide (SP) family WD40 PF00400.27 EGG09671.1 - 2.8e-17 61.8 20.9 8.6e-07 28.6 0.1 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.1 EGG09671.1 - 0.02 15.1 0.0 0.67 10.3 0.0 3.3 4 0 0 4 4 4 0 PQQ-like domain DUF4600 PF15372.1 EGG09671.1 - 1.5 9.0 7.8 12 6.1 4.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Ribosomal_L5_C PF00673.16 EGG09675.1 - 3.5e-24 84.3 0.0 5.2e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EGG09675.1 - 4.8e-21 74.2 0.0 1e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Methyltransf_16 PF10294.4 EGG09677.1 - 5e-16 58.6 0.0 3.6e-14 52.5 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGG09677.1 - 0.042 13.2 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EGG09677.1 - 0.046 14.2 0.0 0.079 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DNA_ligase_A_N PF04675.9 EGG09678.1 - 8.9e-40 136.3 0.0 2.4e-39 134.9 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 EGG09678.1 - 8.1e-35 120.0 1.1 1.7e-32 112.4 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 EGG09678.1 - 3.1e-19 69.1 0.0 8e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Synaptonemal_3 PF15191.1 EGG09678.1 - 0.049 13.3 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 Pkinase PF00069.20 EGG09679.1 - 1.4e-72 243.9 0.0 1.7e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG09679.1 - 5.5e-47 160.0 0.0 7.2e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG09679.1 - 1.5e-07 30.6 0.0 6.4e-05 22.0 0.0 2.3 2 1 0 2 2 2 2 Kinase-like SRC-1 PF08832.5 EGG09680.1 - 0.15 12.8 0.4 0.15 12.8 0.3 1.8 1 1 1 2 2 2 0 Steroid receptor coactivator Spc7 PF08317.6 EGG09681.1 - 0.013 14.2 3.5 0.022 13.4 2.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Wbp11 PF09429.5 EGG09681.1 - 0.43 10.5 4.0 13 5.8 0.1 2.6 1 1 1 2 2 2 0 WW domain binding protein 11 Glyco_tranf_2_4 PF13704.1 EGG09682.1 - 0.078 13.2 0.1 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 Alpha_kinase PF02816.13 EGG09684.1 - 5.1e-24 84.9 0.9 7.3e-24 84.4 0.6 1.4 1 0 0 1 1 1 1 Alpha-kinase family PXB PF12828.2 EGG09684.1 - 0.027 14.0 0.1 0.067 12.7 0.1 1.6 2 0 0 2 2 2 0 PX-associated Prim_Zn_Ribbon PF08273.7 EGG09684.1 - 0.077 13.0 0.6 0.6 10.2 0.1 2.2 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Snapin_Pallidin PF14712.1 EGG09685.1 - 0.1 12.9 0.1 0.36 11.1 0.0 1.9 1 1 0 1 1 1 0 Snapin/Pallidin HDV_ag PF01517.13 EGG09686.1 - 0.17 11.5 2.5 0.25 11.0 1.7 1.1 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Blo-t-5 PF11642.3 EGG09687.1 - 0.0061 16.2 1.7 0.0078 15.9 1.0 1.4 1 1 0 1 1 1 1 Mite allergen Blo t 5 DUF842 PF05811.8 EGG09687.1 - 0.023 14.1 0.5 0.27 10.6 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DUF2439 PF10382.4 EGG09687.1 - 0.044 13.9 1.3 0.11 12.7 0.1 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2439) Enolase_C PF00113.17 EGG09687.1 - 0.048 12.6 0.6 0.056 12.4 0.4 1.2 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain DUF501 PF04417.7 EGG09687.1 - 0.049 13.4 0.1 0.062 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF842 PF05811.8 EGG09688.1 - 0.016 14.6 0.5 0.27 10.6 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Blo-t-5 PF11642.3 EGG09688.1 - 0.034 13.9 1.6 0.044 13.5 0.9 1.4 1 1 0 1 1 1 0 Mite allergen Blo t 5 DUF501 PF04417.7 EGG09688.1 - 0.041 13.7 0.1 0.054 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF2439 PF10382.4 EGG09688.1 - 0.044 14.0 1.3 0.11 12.7 0.1 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2439) Enolase_C PF00113.17 EGG09688.1 - 0.048 12.6 0.6 0.057 12.3 0.4 1.2 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain ABC_membrane_2 PF06472.10 EGG09689.1 - 1.3e-09 37.5 1.2 1.5e-09 37.4 0.8 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 DivIC PF04977.10 EGG09695.1 - 0.0093 15.4 1.5 0.74 9.3 0.0 2.6 2 1 1 3 3 3 1 Septum formation initiator MAD PF05557.8 EGG09695.1 - 0.013 13.5 0.9 0.017 13.2 0.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein FlaC_arch PF05377.6 EGG09695.1 - 0.022 14.6 0.6 0.87 9.5 0.0 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2392 PF10288.4 EGG09695.1 - 0.027 14.8 0.2 0.039 14.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) DASH_Spc19 PF08287.6 EGG09695.1 - 0.03 13.9 0.7 0.059 12.9 0.2 1.6 1 1 1 2 2 2 0 Spc19 Reo_sigmaC PF04582.7 EGG09695.1 - 0.042 13.0 0.3 0.048 12.8 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Prefoldin_2 PF01920.15 EGG09695.1 - 0.1 12.3 1.8 9.2 6.0 0.0 2.7 2 1 0 2 2 2 0 Prefoldin subunit IncA PF04156.9 EGG09695.1 - 0.13 11.8 1.3 0.3 10.6 0.7 1.7 1 1 0 1 1 1 0 IncA protein Noelin-1 PF12308.3 EGG09695.1 - 0.13 12.0 0.2 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF4559 PF15112.1 EGG09695.1 - 0.14 11.3 4.9 0.24 10.5 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Dzip-like_N PF13815.1 EGG09695.1 - 0.14 11.9 1.1 0.27 11.0 0.8 1.6 1 1 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Lzipper-MIP1 PF14389.1 EGG09695.1 - 0.15 12.2 1.8 0.57 10.3 1.0 2.1 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FlxA PF14282.1 EGG09695.1 - 0.2 11.6 1.8 2.9 7.8 0.9 2.2 2 1 0 2 2 2 0 FlxA-like protein ORF6C PF10552.4 EGG09695.1 - 0.25 11.1 2.0 0.52 10.0 0.2 2.1 2 1 0 2 2 2 0 ORF6C domain DUF2018 PF09442.5 EGG09695.1 - 1.3 9.6 3.8 75 3.9 2.7 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2018) LRR_4 PF12799.2 EGG09700.1 - 0.00058 19.4 4.3 0.0033 17.0 0.4 3.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) MoeZ_MoeB PF05237.8 EGG09700.1 - 0.083 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 MoeZ/MoeB domain LRR_2 PF07723.8 EGG09700.1 - 9 6.9 7.1 24 5.6 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat DUF1515 PF07439.6 EGG09702.1 - 0.061 13.1 0.6 0.14 12.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) HMG_box PF00505.14 EGG09702.1 - 0.21 11.8 3.2 12 6.2 0.1 2.9 3 0 0 3 3 3 0 HMG (high mobility group) box SET PF00856.23 EGG09702.1 - 6.2 7.0 9.2 2.7 8.2 1.1 3.0 2 1 0 2 2 2 0 SET domain UQ_con PF00179.21 EGG09705.1 - 7.2e-42 142.1 0.0 8.1e-42 141.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGG09705.1 - 0.0047 16.6 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGG09705.1 - 0.056 13.3 0.1 0.081 12.8 0.0 1.4 1 1 0 1 1 1 0 RWD domain Cu_bind_like PF02298.12 EGG09707.1 - 0.06 13.1 0.5 0.4 10.5 0.3 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain Lactamase_B PF00753.22 EGG09708.1 - 1.6e-12 47.4 0.0 3.2e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGG09708.1 - 1.2e-06 28.2 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HECT PF00632.20 EGG09709.1 - 4.9e-90 301.9 0.1 6.6e-90 301.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EGG09709.1 - 6e-33 112.3 17.7 2.1e-11 43.4 1.4 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EGG09709.1 - 6.4e-16 57.9 0.3 1.5e-15 56.7 0.2 1.7 1 0 0 1 1 1 1 C2 domain TFIIA PF03153.8 EGG09709.1 - 0.74 9.6 7.7 1.2 8.9 5.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF155 PF02582.9 EGG09710.1 - 2.4e-31 108.9 0.0 3.4e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 FeoC PF09012.5 EGG09712.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator PI3_PI4_kinase PF00454.22 EGG09713.1 - 1.9e-32 112.6 0.1 2.6e-30 105.6 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EGG09713.1 - 1.3e-21 76.6 0.0 3.4e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) FA_hydroxylase PF04116.8 EGG09714.1 - 8.6e-16 58.3 12.8 8.6e-16 58.3 8.9 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily CAP_N PF01213.14 EGG09715.1 - 1.4e-92 310.3 0.0 2.3e-92 309.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EGG09715.1 - 2.4e-61 205.7 6.1 3.3e-61 205.2 4.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EGG09715.1 - 0.0062 15.9 0.8 0.013 14.9 0.5 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF3506 PF12014.3 EGG09719.1 - 1.5e-10 41.0 0.6 1.6e-08 34.4 0.4 3.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) RRM_1 PF00076.17 EGG09720.1 - 1.3e-17 63.1 0.1 1.9e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG09720.1 - 4.6e-12 45.7 0.0 8.5e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG09720.1 - 5.5e-11 42.1 0.1 2.3e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MCC-bdg_PDZ PF10506.4 EGG09720.1 - 0.02 14.7 0.1 0.42 10.4 0.3 2.1 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TIP_N PF12457.3 EGG09723.1 - 0.17 11.9 2.9 0.23 11.5 0.6 2.2 1 1 1 2 2 2 0 Tuftelin interacting protein N terminal Cellulase PF00150.13 EGG09724.1 - 5.2e-13 48.8 0.0 9.6e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MarB PF13999.1 EGG09725.1 - 0.099 12.2 0.7 0.19 11.3 0.5 1.6 1 1 0 1 1 1 0 MarB protein HMG_box PF00505.14 EGG09726.1 - 0.041 14.1 0.1 0.66 10.2 0.0 2.6 2 0 0 2 2 2 0 HMG (high mobility group) box TatD_DNase PF01026.16 EGG09727.1 - 0.056 12.6 0.0 0.058 12.5 0.0 1.0 1 0 0 1 1 1 0 TatD related DNase Glyco_transf_15 PF01793.11 EGG09728.1 - 6e-96 321.2 15.9 9.8e-89 297.5 7.7 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase DUF2129 PF09902.4 EGG09728.1 - 0.046 13.5 0.1 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) BUD22 PF09073.5 EGG09729.1 - 0.08 11.9 0.4 0.095 11.7 0.3 1.0 1 0 0 1 1 1 0 BUD22 ParBc PF02195.13 EGG09730.1 - 0.078 13.0 0.0 0.29 11.2 0.0 1.9 1 1 1 2 2 2 0 ParB-like nuclease domain SAP PF02037.22 EGG09733.1 - 0.0036 16.7 1.7 0.0061 16.0 1.2 1.4 1 0 0 1 1 1 1 SAP domain TFIIA PF03153.8 EGG09733.1 - 0.27 11.0 22.6 0.43 10.4 15.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Trypan_PARP PF05887.6 EGG09733.1 - 0.52 10.1 24.8 1.1 9.1 17.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Spore_coat_CotO PF14153.1 EGG09733.1 - 1.7 8.0 25.6 0.33 10.3 14.2 2.1 2 1 0 2 2 2 0 Spore coat protein CotO Pkinase PF00069.20 EGG09734.1 - 2e-51 174.6 0.0 2.4e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG09734.1 - 6.6e-45 153.2 0.0 7.5e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG09734.1 - 0.00046 19.9 0.1 0.0062 16.3 0.0 2.4 2 1 0 3 3 3 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.19 EGG09736.1 - 1e-47 162.0 0.4 1.5e-47 161.4 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGG09736.1 - 2.9e-24 85.8 0.0 5.6e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGG09736.1 - 3.8e-24 83.9 0.4 1.4e-23 82.1 0.3 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGG09736.1 - 5.1e-15 55.8 0.1 8.1e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EGG09736.1 - 0.0024 17.3 0.2 0.0066 15.8 0.1 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Cpn60_TCP1 PF00118.19 EGG09737.1 - 2.3e-140 468.4 13.4 2.6e-140 468.2 9.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1399 PF07173.7 EGG09738.1 - 7.2e-13 49.0 10.0 2.6e-11 43.9 0.0 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF1399) Methyltransf_16 PF10294.4 EGG09739.1 - 2e-20 72.9 0.0 2.8e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EGG09739.1 - 9.2e-05 22.2 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG09739.1 - 0.00093 19.7 0.0 0.0019 18.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG09739.1 - 0.024 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EGG09739.1 - 0.054 13.9 0.1 0.18 12.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MethyltransfD12 PF02086.10 EGG09739.1 - 0.083 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.8 EGG09739.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 6PGD PF00393.14 EGG09740.1 - 4.6e-132 439.6 0.0 5.7e-132 439.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGG09740.1 - 1.6e-50 171.0 0.0 2.3e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGG09740.1 - 0.028 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ApbA PF02558.11 EGG09740.1 - 0.034 13.5 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TFIID-18kDa PF02269.11 EGG09741.1 - 1.9e-30 104.4 0.1 7.1e-30 102.6 0.1 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit FISNA PF14484.1 EGG09741.1 - 0.051 13.5 0.5 0.12 12.4 0.4 1.6 1 0 0 1 1 1 0 Fish-specific NACHT associated domain Abhydrolase_1 PF00561.15 EGG09742.1 - 3e-19 69.5 0.0 3.9e-15 56.0 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGG09742.1 - 3.1e-07 30.4 0.0 7.5e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 EGG09742.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ndc1_Nup PF09531.5 EGG09745.1 - 6.1e-59 199.9 5.4 7.6e-59 199.6 3.7 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Ion_trans PF00520.26 EGG09746.1 - 0.035 13.3 2.6 0.049 12.8 1.8 1.2 1 0 0 1 1 1 0 Ion transport protein MBOAT_2 PF13813.1 EGG09747.1 - 3.5e-10 39.8 2.5 6.8e-10 38.8 1.7 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ECH PF00378.15 EGG09754.1 - 3.7e-78 262.0 0.1 4.2e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EGG09754.1 - 4.9e-05 23.1 0.2 0.012 15.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 ECH_C PF13766.1 EGG09754.1 - 0.00035 20.6 0.0 0.00078 19.5 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_C31 PF05410.8 EGG09754.1 - 0.05 13.4 0.0 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Porcine arterivirus-type cysteine proteinase alpha Cellulase PF00150.13 EGG09755.1 - 6.4e-15 55.1 0.1 1.2e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fil_haemagg_2 PF13332.1 EGG09760.1 - 0.057 13.1 5.4 1.1 9.0 3.7 2.0 1 1 0 1 1 1 0 Haemagluttinin repeat Hce2 PF14856.1 EGG09763.1 - 1.8e-06 27.7 3.0 0.0027 17.5 0.3 2.4 2 0 0 2 2 2 2 Pathogen effector; putative necrosis-inducing factor Peptidase_C93 PF06035.6 EGG09763.1 - 0.022 14.1 0.1 5.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial transglutaminase-like cysteine proteinase BTLCP TRAM_LAG1_CLN8 PF03798.11 EGG09764.1 - 6.4e-38 130.2 21.2 6.4e-38 130.2 14.7 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EGG09764.1 - 3.2e-12 45.7 0.2 2.7e-11 42.7 0.0 2.5 2 0 0 2 2 2 1 TRAM1-like protein EI24 PF07264.6 EGG09765.1 - 2.9e-17 62.8 7.5 5e-17 62.0 5.2 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Uteroglobin PF01099.12 EGG09766.1 - 0.009 15.7 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 2 Uteroglobin family E1-E2_ATPase PF00122.15 EGG09767.1 - 3.7e-68 229.0 12.0 8.4e-68 227.8 6.3 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGG09767.1 - 8.6e-45 152.4 6.3 8.6e-45 152.4 4.4 2.7 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGG09767.1 - 2e-34 119.8 0.1 4.3e-33 115.5 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGG09767.1 - 4.3e-22 77.8 0.1 1e-21 76.6 0.1 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGG09767.1 - 3.3e-17 63.2 0.0 8.7e-17 61.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGG09767.1 - 1.1e-16 59.9 0.2 1.1e-16 59.9 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGG09767.1 - 2.7e-07 30.4 4.2 9.2e-06 25.4 0.5 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGG09767.1 - 0.0027 17.9 0.0 0.0077 16.4 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Amidohydro_2 PF04909.9 EGG09768.1 - 6.1e-25 88.2 0.0 8.9e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase MRP-S28 PF10213.4 EGG09769.1 - 8.7e-20 71.0 0.0 1.6e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein TMV_coat PF00721.16 EGG09770.1 - 0.09 12.6 4.9 0.22 11.4 0.0 2.9 2 1 1 3 3 3 0 Virus coat protein (TMV like) UFD1 PF03152.9 EGG09771.1 - 6.4e-60 201.2 0.0 8.3e-60 200.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Abhydrolase_6 PF12697.2 EGG09772.1 - 1.7e-12 47.6 0.0 2.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG09772.1 - 0.00027 20.5 0.0 0.0024 17.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG09772.1 - 0.0055 16.4 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family SCAMP PF04144.8 EGG09773.1 - 1.1e-45 155.6 6.1 1.3e-45 155.4 4.2 1.1 1 0 0 1 1 1 1 SCAMP family Nup54 PF13874.1 EGG09773.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 TIP120 PF08623.5 EGG09774.1 - 5.9e-55 185.4 3.6 1.9e-53 180.4 0.2 4.1 3 1 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EGG09774.1 - 7.4e-18 64.6 12.7 0.0019 18.4 0.0 9.6 8 3 2 10 10 10 4 HEAT repeats HEAT PF02985.17 EGG09774.1 - 5.1e-14 51.0 18.4 0.003 17.4 0.0 11.0 13 0 0 13 13 9 4 HEAT repeat HEAT_EZ PF13513.1 EGG09774.1 - 3.8e-11 43.1 14.7 0.41 11.1 0.0 12.0 12 3 3 15 15 15 3 HEAT-like repeat Cnd1 PF12717.2 EGG09774.1 - 1.1e-07 31.8 10.9 0.0035 17.2 0.0 7.6 5 3 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EGG09774.1 - 4e-05 23.4 2.5 0.21 11.5 0.0 4.9 5 0 0 5 5 5 1 Protein of unknown function (DUF2435) API5 PF05918.6 EGG09774.1 - 0.0016 17.0 1.4 0.07 11.6 0.0 3.4 4 0 0 4 4 4 1 Apoptosis inhibitory protein 5 (API5) Sigma70_ner PF04546.8 EGG09774.1 - 0.012 15.2 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region VHS PF00790.14 EGG09774.1 - 0.017 14.7 0.3 0.28 10.8 0.0 3.3 2 0 0 2 2 2 0 VHS domain Arm PF00514.18 EGG09774.1 - 0.31 10.9 9.2 38 4.3 0.0 6.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 EGG09774.1 - 0.46 9.5 9.9 0.15 11.1 0.8 3.8 4 2 0 4 4 4 0 V-ATPase subunit H V-ATPase_H_C PF11698.3 EGG09774.1 - 4 7.3 6.7 3.4 7.6 0.0 3.8 4 0 0 4 4 4 0 V-ATPase subunit H ParcG PF10274.4 EGG09774.1 - 4.9 7.0 6.8 35 4.2 0.2 4.4 5 1 1 6 6 6 0 Parkin co-regulated protein Sec66 PF09802.4 EGG09775.1 - 1.5e-18 66.8 0.1 1.9e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Glyco_transf_18 PF15024.1 EGG09777.1 - 7.3e-09 34.5 0.0 2.8e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 18 Chitin_synth_1N PF08407.6 EGG09778.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Chitin synthase N-terminal Glyco_transf_18 PF15024.1 EGG09779.1 - 7.8e-14 50.9 0.0 1.2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 WD40 PF00400.27 EGG09780.1 - 1.5e-26 91.2 15.9 6.3e-07 29.0 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Frankia_peptide PF14407.1 EGG09780.1 - 0.13 12.0 3.7 0.18 11.5 0.4 2.8 3 0 0 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Antifungal_pept PF11410.3 EGG09781.1 - 0.14 12.2 0.6 0.29 11.2 0.4 1.4 1 0 0 1 1 1 0 Antifungal peptide PAC2 PF09754.4 EGG09782.1 - 2.3e-18 66.8 0.0 3.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 PAC2 family Peptidase_S28 PF05577.7 EGG09784.1 - 9.2e-48 162.8 0.1 2.4e-46 158.2 0.1 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Ras PF00071.17 EGG09785.1 - 3.5e-49 166.2 0.0 4.1e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG09785.1 - 1.7e-12 47.9 0.0 2.3e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG09785.1 - 9.6e-06 24.9 0.0 2.1e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 EGG09785.1 - 0.021 14.9 0.0 0.48 10.5 0.0 2.6 2 1 1 3 3 3 0 AAA domain DAP3 PF10236.4 EGG09785.1 - 0.039 12.8 0.1 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Peptidase_S8 PF00082.17 EGG09786.1 - 2.1e-54 184.5 0.5 2.9e-54 184.1 0.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EGG09786.1 - 5.6e-26 90.1 0.3 1.9e-25 88.4 0.1 2.1 2 0 0 2 2 2 1 Proprotein convertase P-domain Hist_deacetyl PF00850.14 EGG09787.1 - 1.1e-82 277.8 0.0 1.3e-82 277.5 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain 6PF2K PF01591.13 EGG09789.1 - 1.1e-69 233.9 0.4 7.5e-66 221.3 0.0 2.2 1 1 1 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGG09789.1 - 2.5e-33 115.3 0.2 1.1e-32 113.2 0.0 2.2 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EGG09789.1 - 1.5e-08 34.6 0.0 2.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG09789.1 - 0.0001 23.0 0.2 0.0008 20.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGG09789.1 - 0.00032 19.8 0.0 0.00067 18.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Methyltransf_32 PF13679.1 EGG09789.1 - 0.00079 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain KTI12 PF08433.5 EGG09789.1 - 0.019 14.1 0.1 0.038 13.2 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 GBP PF02263.14 EGG09789.1 - 0.06 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Vac_ImportDeg PF09783.4 EGG09790.1 - 6.1e-39 133.3 0.3 8.2e-34 116.6 0.0 2.3 2 0 0 2 2 2 2 Vacuolar import and degradation protein DUF3401 PF11881.3 EGG09790.1 - 0.028 13.7 1.8 0.041 13.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3401) DUF1619 PF07773.6 EGG09795.1 - 0.13 12.0 0.1 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1619) GYF PF02213.11 EGG09796.1 - 8.1e-05 22.1 0.2 0.00022 20.7 0.1 1.7 1 0 0 1 1 1 1 GYF domain DUF3152 PF11350.3 EGG09798.1 - 0.031 13.7 0.3 0.044 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Inhibitor_Mig-6 PF11555.3 EGG09798.1 - 0.14 12.5 0.0 1.7 9.0 0.0 2.1 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 PBP PF01161.15 EGG09800.1 - 4.3e-12 46.0 0.0 6.9e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FlgD_ig PF13860.1 EGG09800.1 - 0.055 13.2 0.1 0.84 9.4 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain Mago_nashi PF02792.9 EGG09804.1 - 7.7e-66 220.1 0.5 9e-66 219.9 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein F-box-like PF12937.2 EGG09805.1 - 0.00089 18.9 0.0 0.0044 16.6 0.0 2.2 1 0 0 1 1 1 1 F-box-like Octopine_DH PF02317.12 EGG09806.1 - 0.23 11.0 2.2 0.48 10.0 1.5 1.4 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Asp-B-Hydro_N PF05279.6 EGG09806.1 - 2.5 7.8 22.6 3.7 7.3 15.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CAF-1_p150 PF11600.3 EGG09806.1 - 6.2 6.1 40.5 2.6 7.3 25.5 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal EKR PF10371.4 EGG09807.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF43 PF01861.11 EGG09810.1 - 0.016 14.2 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 TPR_2 PF07719.12 EGG09811.1 - 0.0026 17.5 0.4 0.89 9.6 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGG09811.1 - 0.0093 16.6 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat GHL13 PF14883.1 EGG09811.1 - 0.027 13.6 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 PPR PF01535.15 EGG09811.1 - 0.044 13.7 0.1 1.8 8.7 0.1 2.6 2 0 0 2 2 2 0 PPR repeat TPR_12 PF13424.1 EGG09811.1 - 0.15 12.0 0.1 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Y_phosphatase2 PF03162.8 EGG09814.1 - 1.5e-35 121.9 0.0 1.7e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EGG09814.1 - 7.3e-07 29.5 0.0 2.9e-06 27.6 0.0 1.7 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EGG09814.1 - 0.00033 20.2 0.0 0.00036 20.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGG09814.1 - 0.00072 18.9 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RRM_1 PF00076.17 EGG09816.1 - 1.2e-15 56.9 0.0 2e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG09816.1 - 1.6e-15 56.7 0.0 3.2e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG09816.1 - 3.2e-08 33.2 0.0 5.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGG09816.1 - 0.0046 16.7 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Spc24 PF08286.6 EGG09816.1 - 0.39 10.4 2.2 0.54 9.9 1.5 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Helicase_C PF00271.26 EGG09818.1 - 1.6e-15 56.6 0.1 4e-15 55.4 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGG09818.1 - 4.5e-07 29.5 0.0 1.8e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EGG09818.1 - 0.042 12.6 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain CAF1A PF12253.3 EGG09819.1 - 1.9e-21 75.9 2.5 6.2e-21 74.3 1.7 1.9 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A DUF4440 PF14534.1 EGG09821.1 - 0.027 14.6 0.0 0.035 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) CIDE-N PF02017.10 EGG09821.1 - 0.047 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 CIDE-N domain MalM PF07148.7 EGG09823.1 - 0.0079 15.6 0.3 0.14 11.5 0.0 2.2 2 0 0 2 2 2 1 Maltose operon periplasmic protein precursor (MalM) SIMPL PF04402.9 EGG09823.1 - 0.024 14.4 4.8 1.4 8.7 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF541) DUF2138 PF09909.4 EGG09823.1 - 0.026 12.7 0.3 1.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2138) RHH_1 PF01402.16 EGG09823.1 - 0.047 13.5 1.3 9.1 6.3 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Histone_HNS PF00816.16 EGG09823.1 - 0.15 12.5 7.8 3.1 8.3 1.2 2.2 2 0 0 2 2 2 0 H-NS histone family DUF3168 PF11367.3 EGG09823.1 - 0.29 11.3 2.3 6.6 6.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) Rotamase_2 PF13145.1 EGG09823.1 - 1.7 9.3 7.8 2.9 8.5 0.3 2.5 3 0 0 3 3 3 0 PPIC-type PPIASE domain DnaJ PF00226.26 EGG09823.1 - 6.7 6.5 7.3 7.6 6.3 0.3 2.8 2 2 0 2 2 2 0 DnaJ domain HTH_11 PF08279.7 EGG09824.1 - 0.032 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 HTH domain PulG PF11773.3 EGG09824.1 - 0.093 12.4 0.1 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin Oxidored_FMN PF00724.15 EGG09827.1 - 2.5e-37 128.6 0.0 3.5e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Alpha_kinase PF02816.13 EGG09828.1 - 6.5e-06 25.9 0.1 1e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family DUF2315 PF10231.4 EGG09829.1 - 1.4e-06 28.2 7.3 0.0016 18.3 3.0 2.5 2 1 0 2 2 2 2 Uncharacterised conserved protein (DUF2315) Glycos_transf_1 PF00534.15 EGG09830.1 - 3.1e-22 78.8 0.0 8.7e-22 77.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGG09830.1 - 2.8e-12 46.7 0.1 4.2e-11 42.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EGG09830.1 - 2.7e-09 37.3 0.0 6.1e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EGG09830.1 - 5.6e-07 29.7 0.0 1.3e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGG09830.1 - 0.00067 19.8 0.0 0.0042 17.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 CoxIIa PF08113.6 EGG09830.1 - 0.22 11.2 1.9 0.48 10.2 1.3 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family VRR_NUC PF08774.6 EGG09831.1 - 1.2e-16 60.5 0.0 3.5e-16 59.0 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain TAF PF02969.12 EGG09832.1 - 3.4e-28 97.3 0.2 1.1e-27 95.7 0.0 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 EGG09832.1 - 3.8e-17 62.1 0.1 7.7e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 EGG09832.1 - 5.6e-06 26.3 0.2 1.7e-05 24.8 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TP_methylase PF00590.15 EGG09832.1 - 0.033 13.9 0.4 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases RuvB_N PF05496.7 EGG09832.1 - 0.047 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Methyltransf_10 PF05971.7 EGG09833.1 - 1e-42 146.3 0.0 1.1e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF890) PrmA PF06325.8 EGG09833.1 - 0.00024 20.3 0.0 0.00031 19.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EGG09833.1 - 0.0023 18.4 0.0 0.008 16.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EGG09833.1 - 0.015 13.9 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MTS PF05175.9 EGG09833.1 - 0.016 14.6 0.0 0.037 13.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain DUF633 PF04816.7 EGG09833.1 - 0.031 13.6 0.0 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF633) Methyltransf_26 PF13659.1 EGG09833.1 - 0.079 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EGG09833.1 - 0.081 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_10 PF05971.7 EGG09834.1 - 3e-14 52.8 0.2 4e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Asp PF00026.18 EGG09835.1 - 4.4e-66 223.2 1.2 5.2e-66 223.0 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG09835.1 - 2.6e-09 37.2 0.0 1.2e-08 35.1 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGG09835.1 - 2e-06 28.2 0.2 0.0014 19.0 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EGG09835.1 - 0.076 12.5 0.0 0.21 11.1 0.0 1.9 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal AAA PF00004.24 EGG09836.1 - 2.6e-17 63.2 0.0 5.1e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EGG09836.1 - 3.2e-14 52.8 0.1 5.9e-13 48.7 0.0 2.6 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EGG09836.1 - 7.1e-09 35.5 0.1 1.8e-08 34.2 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EGG09836.1 - 1.9e-07 30.1 0.1 0.0017 17.1 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EGG09836.1 - 3.7e-07 30.3 0.1 1.3e-05 25.3 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EGG09836.1 - 2.2e-05 24.0 0.0 5.2e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EGG09836.1 - 3.4e-05 23.5 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGG09836.1 - 5.3e-05 23.1 0.0 9.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGG09836.1 - 5.3e-05 22.3 0.0 0.00012 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGG09836.1 - 6.6e-05 22.9 0.1 0.0015 18.5 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 EGG09836.1 - 0.00026 20.2 0.0 0.0057 15.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGG09836.1 - 0.00041 20.0 0.0 0.0012 18.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EGG09836.1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EGG09836.1 - 0.0048 16.3 0.3 0.31 10.4 0.0 2.8 2 2 1 3 3 3 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EGG09836.1 - 0.014 15.6 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGG09836.1 - 0.016 14.6 0.0 0.057 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGG09836.1 - 0.017 14.7 0.0 0.19 11.2 0.0 2.6 3 1 0 3 3 3 0 AAA domain DUF815 PF05673.8 EGG09836.1 - 0.018 13.9 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2075 PF09848.4 EGG09836.1 - 0.02 13.9 0.0 0.038 12.9 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EGG09836.1 - 0.03 15.1 0.0 0.058 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EGG09836.1 - 0.038 13.5 0.0 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGG09836.1 - 0.042 13.8 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EGG09836.1 - 0.047 13.1 0.0 0.39 10.1 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_10 PF12846.2 EGG09836.1 - 0.048 13.0 0.1 0.69 9.2 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EGG09836.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.1 EGG09836.1 - 0.13 12.0 0.0 0.33 10.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain ResIII PF04851.10 EGG09836.1 - 0.16 11.8 0.0 0.5 10.1 0.0 1.7 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Pyridoxal_deC PF00282.14 EGG09837.1 - 3e-100 335.2 0.0 1.2e-65 221.4 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 EGG09837.1 - 0.042 12.7 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II RPE65 PF03055.10 EGG09838.1 - 2.5e-113 379.2 0.0 2.9e-113 379.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein CDC45 PF02724.9 EGG09839.1 - 2.4e-198 660.1 0.0 2.7e-198 659.9 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein GAT PF03127.9 EGG09840.1 - 0.025 14.5 0.7 0.072 13.0 0.5 1.7 1 0 0 1 1 1 0 GAT domain USP7_ICP0_bdg PF12436.3 EGG09841.1 - 2e-86 289.2 0.4 7.7e-86 287.3 0.1 2.0 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EGG09841.1 - 2.6e-67 226.3 0.2 2.3e-61 206.9 0.1 4.2 4 0 0 4 4 4 3 Ubiquitin-specific protease C-terminal UCH PF00443.24 EGG09841.1 - 7.5e-56 189.2 0.0 1.3e-55 188.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGG09841.1 - 9.7e-33 113.8 0.0 2.3e-32 112.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EGG09841.1 - 1e-11 45.0 1.5 8.5e-10 38.9 0.0 3.9 4 0 0 4 4 4 1 MATH domain HSDR_N_2 PF13588.1 EGG09841.1 - 0.0075 16.0 0.0 0.028 14.2 0.0 2.0 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) ABC_tran PF00005.22 EGG09842.1 - 1.9e-44 151.2 0.1 1.3e-23 83.7 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGG09842.1 - 1.3e-20 74.5 2.3 2.3e-06 27.7 0.1 4.0 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 EGG09842.1 - 2.7e-14 52.9 0.3 0.0057 15.9 0.0 4.3 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain HEAT_2 PF13646.1 EGG09842.1 - 7e-09 35.8 5.5 0.0012 19.1 0.5 3.8 4 0 0 4 4 3 2 HEAT repeats AAA_29 PF13555.1 EGG09842.1 - 9.8e-09 34.6 0.0 0.0026 17.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EGG09842.1 - 3.5e-07 31.0 0.1 0.0071 17.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGG09842.1 - 4.9e-07 29.5 0.0 0.0026 17.6 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EGG09842.1 - 5.1e-07 29.4 0.0 0.067 12.6 0.0 4.0 5 0 0 5 5 5 2 AAA-like domain AAA_22 PF13401.1 EGG09842.1 - 2.1e-06 27.9 0.0 0.038 14.1 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_18 PF13238.1 EGG09842.1 - 7.8e-06 26.2 0.4 0.0089 16.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 EGG09842.1 - 8.1e-06 25.8 0.0 0.0038 17.0 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_15 PF13175.1 EGG09842.1 - 3.1e-05 23.2 0.3 0.083 11.9 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain HEAT_EZ PF13513.1 EGG09842.1 - 4.3e-05 23.8 6.4 1.5 9.3 0.1 5.6 4 1 1 5 5 5 1 HEAT-like repeat ArgK PF03308.11 EGG09842.1 - 6.6e-05 21.8 1.8 0.55 8.9 0.0 3.4 3 0 0 3 3 3 2 ArgK protein DUF258 PF03193.11 EGG09842.1 - 7.1e-05 22.0 0.0 0.05 12.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EGG09842.1 - 0.00011 22.7 0.0 0.36 11.3 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EGG09842.1 - 0.00011 22.0 0.0 0.64 9.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 EGG09842.1 - 0.00012 21.8 0.0 0.58 9.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 EGG09842.1 - 0.00017 21.8 0.0 3.9 7.6 0.0 4.8 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGG09842.1 - 0.00019 21.3 0.0 0.75 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EGG09842.1 - 0.00033 20.3 0.1 0.44 10.2 0.0 3.0 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGG09842.1 - 0.00033 20.6 4.9 0.0089 16.0 0.3 3.8 3 2 0 3 3 3 1 AAA ATPase domain HEAT PF02985.17 EGG09842.1 - 0.00069 19.4 10.8 0.071 13.2 0.1 5.5 7 0 0 7 7 4 1 HEAT repeat RNA_helicase PF00910.17 EGG09842.1 - 0.00096 19.3 0.0 0.82 9.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Chromo PF00385.19 EGG09842.1 - 0.001 18.7 0.1 0.0028 17.2 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CLASP_N PF12348.3 EGG09842.1 - 0.0011 18.3 0.3 0.0026 17.1 0.1 1.8 2 0 0 2 2 1 1 CLASP N terminal AAA_28 PF13521.1 EGG09842.1 - 0.0014 18.5 0.0 0.77 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EGG09842.1 - 0.0024 17.4 0.1 2.6 7.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_13 PF13166.1 EGG09842.1 - 0.0025 16.3 0.7 1.2 7.5 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.1 EGG09842.1 - 0.0041 16.5 0.0 1.8 7.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EGG09842.1 - 0.0049 16.3 0.1 3.1 7.1 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family MOR2-PAG1_C PF14225.1 EGG09842.1 - 0.012 15.4 0.2 1.4 8.5 0.2 2.3 2 0 0 2 2 2 0 Cell morphogenesis C-terminal Cnd1 PF12717.2 EGG09842.1 - 0.013 15.3 0.0 0.44 10.3 0.0 2.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Arch_ATPase PF01637.13 EGG09842.1 - 0.014 15.0 0.0 6.6 6.3 0.0 2.9 2 0 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 EGG09842.1 - 0.023 14.4 0.0 5.7 6.6 0.0 3.1 3 0 0 3 3 2 0 NTPase AAA_14 PF13173.1 EGG09842.1 - 0.028 14.3 0.0 3 7.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.8 EGG09842.1 - 0.03 13.2 0.2 6.1 5.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EGG09842.1 - 0.037 12.8 0.3 0.94 8.2 0.1 2.5 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.7 EGG09842.1 - 0.039 13.0 0.0 7.7 5.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 EGG09842.1 - 0.042 13.6 1.4 0.97 9.2 0.1 3.0 3 1 0 3 3 2 0 Dynamin family AAA_23 PF13476.1 EGG09842.1 - 0.054 13.8 0.0 0.054 13.8 0.0 3.7 2 1 0 2 2 1 0 AAA domain cobW PF02492.14 EGG09842.1 - 0.059 12.8 0.1 18 4.7 0.1 3.1 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EGG09842.1 - 0.082 12.5 0.1 9 5.9 0.1 2.8 2 1 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EGG09842.1 - 0.094 12.2 0.0 19 4.7 0.0 3.0 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.3 EGG09842.1 - 0.57 7.4 5.7 2.6 5.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) RNA_pol_I_TF PF04090.7 EGG09843.1 - 9.9e-17 60.8 1.6 4.5e-13 48.9 0.2 2.2 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor SPT6_acidic PF14632.1 EGG09845.1 - 0.024 14.8 1.1 2 8.6 0.0 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 UBN2 PF14223.1 EGG09846.1 - 4.4e-05 23.2 0.7 0.00038 20.2 0.0 2.5 2 1 0 3 3 3 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG09846.1 - 0.00039 19.9 1.2 0.0017 17.9 0.0 2.3 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF663 PF04950.7 EGG09847.1 - 1e-93 313.5 0.0 1.6e-93 312.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) 2-oxoacid_dh PF00198.18 EGG09848.1 - 1.2e-64 217.7 0.0 1.4e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) AMP-binding PF00501.23 EGG09849.1 - 1.1e-06 27.3 0.0 1.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme YopE_N PF09020.5 EGG09850.1 - 0.025 14.5 0.2 0.043 13.8 0.1 1.3 1 0 0 1 1 1 0 YopE, N terminal zf-H2C2_2 PF13465.1 EGG09851.1 - 9.6e-30 101.4 29.0 3.6e-07 30.1 0.3 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EGG09851.1 - 6.4e-17 60.7 28.7 0.00036 20.7 1.6 4.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG09851.1 - 3.5e-10 39.4 21.7 0.0032 17.6 0.3 4.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGG09851.1 - 1.2e-08 34.5 14.7 0.01 15.7 1.2 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGG09851.1 - 5.6e-07 29.5 13.2 0.0013 18.8 0.1 4.5 3 2 1 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EGG09851.1 - 0.00047 19.7 3.8 0.26 11.0 0.2 3.5 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-met PF12874.2 EGG09851.1 - 0.0018 18.4 1.9 0.03 14.5 0.1 5.0 4 1 1 5 5 5 2 Zinc-finger of C2H2 type DUF506 PF04720.7 EGG09851.1 - 0.0039 16.8 0.1 0.004 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF506) zf-C2H2_2 PF12756.2 EGG09851.1 - 0.0055 16.7 13.9 0.065 13.3 4.7 2.5 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) Vps39_2 PF10367.4 EGG09851.1 - 0.015 15.4 3.8 1.1 9.4 0.3 2.5 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 C1_4 PF07975.7 EGG09851.1 - 0.022 14.7 10.1 0.63 10.0 1.5 3.0 2 1 1 3 3 3 0 TFIIH C1-like domain Scramblase PF03803.10 EGG09851.1 - 0.026 13.5 0.2 0.052 12.6 0.0 1.4 1 1 1 2 2 2 0 Scramblase Yippee-Mis18 PF03226.9 EGG09851.1 - 0.043 13.8 5.0 2.3 8.3 0.1 2.4 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SAE2 PF08573.5 EGG09851.1 - 0.23 12.1 5.3 1.8 9.3 0.8 2.3 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Prok-RING_1 PF14446.1 EGG09851.1 - 0.54 10.0 5.7 3.7 7.3 0.1 3.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-DBF PF07535.7 EGG09851.1 - 3.8 7.2 7.6 8.4 6.1 0.7 3.1 2 1 0 2 2 2 0 DBF zinc finger adh_short_C2 PF13561.1 EGG09852.1 - 1.2e-32 113.6 0.2 1.5e-32 113.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGG09852.1 - 4.8e-29 101.4 0.1 6.1e-29 101.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG09852.1 - 2.2e-14 53.4 0.1 3.2e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGG09852.1 - 0.0012 18.3 0.1 0.0017 17.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EGG09852.1 - 0.018 15.4 0.2 2.2 8.7 0.1 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PA PF02225.17 EGG09852.1 - 0.1 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 PA domain Pkinase PF00069.20 EGG09854.1 - 2e-46 158.2 0.0 2.7e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG09854.1 - 3e-19 69.0 0.0 3.9e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG09854.1 - 0.00055 18.9 0.0 0.01 14.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGG09854.1 - 0.066 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_1 PF00133.17 EGG09855.1 - 1.5e-142 475.6 0.1 2e-142 475.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EGG09855.1 - 7e-24 84.1 0.1 4.2e-11 42.1 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGG09855.1 - 2.3e-21 76.1 1.2 6.3e-21 74.7 0.9 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGG09855.1 - 2e-07 30.4 0.0 0.0039 16.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 EGG09855.1 - 0.00019 20.7 0.0 0.00062 19.1 0.0 1.8 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.9 EGG09855.1 - 0.0011 18.5 2.0 0.0025 17.3 1.4 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1d PF00750.14 EGG09855.1 - 0.0091 14.8 0.0 0.53 9.0 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1f PF01921.13 EGG09855.1 - 0.048 12.3 0.0 0.093 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) PQ-loop PF04193.9 EGG09859.1 - 0.017 14.6 0.1 0.32 10.5 0.0 2.6 3 0 0 3 3 3 0 PQ loop repeat Per1 PF04080.8 EGG09860.1 - 2.3e-19 69.8 2.0 1.5e-10 40.9 0.2 2.2 2 0 0 2 2 2 2 Per1-like TRAP_alpha PF03896.11 EGG09862.1 - 8 5.3 14.5 18 4.2 10.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit AAA_18 PF13238.1 EGG09863.1 - 1.1e-25 90.3 0.1 3.2e-25 88.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGG09863.1 - 1.3e-12 48.6 0.0 4.1e-12 46.9 0.0 1.7 1 1 1 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EGG09863.1 - 0.00038 20.0 0.1 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.24 EGG09863.1 - 0.00052 20.2 0.0 0.0022 18.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGG09863.1 - 0.0015 18.5 0.1 0.0044 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain dNK PF01712.14 EGG09863.1 - 0.0034 17.3 0.1 0.0045 16.9 0.0 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.12 EGG09863.1 - 0.0069 15.7 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_19 PF13245.1 EGG09863.1 - 0.01 15.5 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EGG09863.1 - 0.011 15.9 0.0 0.039 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EGG09863.1 - 0.013 14.6 0.1 0.071 12.2 0.0 1.9 2 0 0 2 2 2 0 KaiC NTPase_1 PF03266.10 EGG09863.1 - 0.014 15.1 0.5 0.039 13.6 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.1 EGG09863.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EGG09863.1 - 0.03 14.2 0.0 0.55 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EGG09863.1 - 0.032 13.1 0.1 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Prefoldin_3 PF13758.1 EGG09863.1 - 0.042 13.6 0.4 0.22 11.3 0.1 2.1 2 1 1 3 3 3 0 Prefoldin subunit TrwB_AAD_bind PF10412.4 EGG09863.1 - 0.042 12.4 0.0 0.065 11.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Pyr_excise PF03013.9 EGG09863.1 - 0.05 13.3 0.1 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase AAA_10 PF12846.2 EGG09863.1 - 0.057 12.8 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Sigma54_activat PF00158.21 EGG09863.1 - 0.074 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain KTI12 PF08433.5 EGG09863.1 - 0.13 11.4 0.0 0.44 9.7 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 EGG09863.1 - 0.14 12.3 0.0 0.49 10.5 0.0 1.9 2 1 0 2 2 2 0 RNA helicase MFS_1_like PF12832.2 EGG09866.1 - 4.8e-13 48.6 0.2 4.8e-13 48.6 0.1 2.2 2 0 0 2 2 2 1 MFS_1 like family DUF3292 PF11696.3 EGG09868.1 - 0.1 10.4 6.8 0.13 10.1 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) CAF-1_p150 PF11600.3 EGG09868.1 - 0.15 11.4 24.9 0.21 10.9 17.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 EGG09868.1 - 0.41 10.5 11.6 0.56 10.0 8.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_DNAp_acc PF04929.7 EGG09868.1 - 2.1 7.2 9.9 2.6 6.9 6.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SspB PF04386.8 EGG09868.1 - 6.2 6.4 0.0 6.2 6.4 0.0 2.5 1 1 1 2 2 2 0 Stringent starvation protein B PALP PF00291.20 EGG09869.1 - 2e-69 234.1 0.1 2.5e-69 233.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EGG09869.1 - 1.6e-37 126.9 0.2 1.7e-21 75.5 0.0 3.4 2 1 1 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase Ph1570 PF09638.5 EGG09869.1 - 0.036 13.8 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Ph1570 protein DPBB_1 PF03330.13 EGG09870.1 - 8.7e-05 22.4 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel NmrA PF05368.8 EGG09871.1 - 1e-22 80.5 0.2 1.4e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGG09871.1 - 2.4e-09 37.4 0.1 5.7e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGG09871.1 - 5.2e-06 25.3 0.1 8.1e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EGG09871.1 - 0.00079 18.5 0.1 0.0011 18.0 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EGG09871.1 - 0.022 14.6 0.1 0.057 13.3 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 EGG09871.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain adh_short PF00106.20 EGG09871.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 EGG09871.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EGG09872.1 - 5.2e-23 81.5 0.2 7.7e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGG09872.1 - 2.4e-07 30.9 0.4 2.4e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGG09872.1 - 7.6e-06 24.8 0.7 2.8e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EGG09872.1 - 0.0035 17.2 0.1 0.023 14.6 0.1 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EGG09872.1 - 0.019 13.9 0.1 0.032 13.2 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase adh_short PF00106.20 EGG09872.1 - 0.056 13.3 0.1 0.097 12.5 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase LOH1CR12 PF10158.4 EGG09874.1 - 0.35 10.6 4.0 0.34 10.6 2.0 1.5 1 1 0 1 1 1 0 Tumour suppressor protein EssA PF10661.4 EGG09875.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA SAP PF02037.22 EGG09876.1 - 5e-05 22.6 0.7 0.0001 21.6 0.2 1.8 2 0 0 2 2 2 1 SAP domain Dicistro_VP4 PF11492.3 EGG09876.1 - 0.012 15.6 1.1 0.027 14.4 0.4 2.0 1 1 1 2 2 2 0 Cricket paralysis virus, VP4 Rho_N PF07498.7 EGG09876.1 - 0.019 14.7 0.2 0.034 13.9 0.2 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain SRP54_N PF02881.14 EGG09876.1 - 0.032 14.3 1.7 0.046 13.8 0.2 1.9 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain LEM PF03020.10 EGG09876.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 LEM domain IncA PF04156.9 EGG09879.1 - 0.0035 16.9 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 IncA protein Gemini_mov PF01708.11 EGG09879.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 Geminivirus putative movement protein Ribosomal_S30 PF04758.9 EGG09880.1 - 2.1e-24 85.0 6.6 2.3e-24 84.8 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DUF1057 PF06342.7 EGG09884.1 - 0.0062 15.3 0.1 0.031 13.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) TMEM154 PF15102.1 EGG09886.1 - 0.0022 17.6 0.1 0.0035 17.0 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family Pkinase PF00069.20 EGG09887.1 - 9.3e-48 162.6 0.1 1.4e-47 162.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG09887.1 - 8.1e-24 84.0 0.0 1.2e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGG09887.1 - 0.001 17.9 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EGG09887.1 - 0.0017 17.7 0.5 0.019 14.3 0.4 2.2 1 1 0 1 1 1 1 RIO1 family DUF3772 PF12607.3 EGG09891.1 - 0.12 11.9 3.7 4.8 6.8 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) Menin PF05053.8 EGG09891.1 - 4.8 5.2 6.5 5.8 4.9 4.5 1.0 1 0 0 1 1 1 0 Menin DUF1183 PF06682.7 EGG09892.1 - 0.018 14.6 1.5 0.017 14.7 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) FCH PF00611.18 EGG09896.1 - 0.033 14.3 0.1 0.28 11.3 0.0 2.5 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Mpp10 PF04006.7 EGG09896.1 - 0.22 9.8 11.3 0.41 8.9 7.8 1.4 1 0 0 1 1 1 0 Mpp10 protein Glyco_hydro_10 PF00331.15 EGG09898.1 - 2.8e-88 296.0 0.0 3.3e-88 295.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 LeuA_dimer PF08502.5 EGG09898.1 - 0.13 12.0 0.1 0.68 9.7 0.0 2.1 3 0 0 3 3 3 0 LeuA allosteric (dimerisation) domain DUF2890 PF11081.3 EGG09899.1 - 0.00079 19.5 0.6 0.0011 19.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) GCM PF03615.10 EGG09899.1 - 0.06 12.9 0.7 0.13 11.8 0.5 1.5 1 0 0 1 1 1 0 GCM motif protein Hormone_5 PF00184.12 EGG09899.1 - 0.083 13.4 1.4 0.15 12.6 1.0 1.4 1 0 0 1 1 1 0 Neurohypophysial hormones, C-terminal Domain TRAP_alpha PF03896.11 EGG09899.1 - 0.93 8.4 6.5 1.7 7.5 4.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 EGG09899.1 - 1.7 6.4 9.9 2.2 6.0 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 EGG09899.1 - 3.3 7.9 10.3 5.7 7.2 7.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ferritin_2 PF13668.1 EGG09902.1 - 6.7e-38 129.7 1.1 7.8e-38 129.5 0.8 1.1 1 0 0 1 1 1 1 Ferritin-like domain CHORD PF04968.7 EGG09903.1 - 7.3e-50 167.0 17.6 1.1e-25 89.6 4.0 2.5 2 0 0 2 2 2 2 CHORD CS PF04969.11 EGG09903.1 - 3.3e-15 56.3 0.6 8e-15 55.1 0.4 1.7 1 0 0 1 1 1 1 CS domain BTK PF00779.14 EGG09903.1 - 0.027 14.0 4.6 1.7 8.2 0.4 3.1 2 0 0 2 2 2 0 BTK motif Conotoxin PF02950.12 EGG09904.1 - 0.04 14.7 0.2 0.055 14.2 0.2 1.2 1 0 0 1 1 1 0 Conotoxin HhH-GPD PF00730.20 EGG09905.1 - 2e-16 60.2 0.0 2.8e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein B56 PF01603.15 EGG09908.1 - 1.7e-167 557.1 2.3 2.5e-167 556.6 1.6 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) TAFII55_N PF04658.8 EGG09910.1 - 1.1e-46 158.3 1.3 1.1e-46 158.3 0.9 1.7 2 0 0 2 2 2 1 TAFII55 protein conserved region SGT1 PF07093.6 EGG09910.1 - 0.01 14.2 11.4 0.012 13.9 7.9 1.1 1 0 0 1 1 1 1 SGT1 protein DUF1699 PF08004.6 EGG09910.1 - 0.01 15.3 0.3 4.3 6.8 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1699) Surfac_D-trimer PF09006.6 EGG09910.1 - 0.093 12.4 0.3 0.23 11.1 0.2 1.6 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation DUF506 PF04720.7 EGG09910.1 - 0.27 10.8 2.8 0.54 9.8 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF506) CDC45 PF02724.9 EGG09910.1 - 0.36 8.8 10.6 0.45 8.4 7.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGG09910.1 - 1.5 6.6 22.1 1.9 6.2 15.3 1.1 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.6 EGG09910.1 - 2.3 7.3 14.3 3.1 6.8 9.5 1.5 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Sigma70_ner PF04546.8 EGG09910.1 - 2.3 7.8 28.0 8.3e+02 -0.6 19.4 2.3 1 1 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 EGG09910.1 - 2.5 7.1 6.4 40 3.2 5.0 2.1 2 0 0 2 2 2 0 Myc amino-terminal region RRN3 PF05327.6 EGG09910.1 - 6.5 4.7 9.5 9.8 4.1 6.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM70 PF14967.1 EGG09912.1 - 3.9 6.5 6.5 6.3 5.9 4.5 1.3 1 0 0 1 1 1 0 FAM70 protein HMGL-like PF00682.14 EGG09913.1 - 5e-64 216.1 0.0 1e-63 215.1 0.0 1.5 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.5 EGG09913.1 - 7.1e-22 77.6 0.4 1.3e-21 76.7 0.3 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Lipase_GDSL PF00657.17 EGG09914.1 - 1.2e-24 87.4 0.0 1.5e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EGG09914.1 - 4.2e-24 85.6 0.5 5.4e-24 85.3 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4267 PF14087.1 EGG09915.1 - 0.018 14.6 1.1 0.027 14.0 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) UPF0104 PF03706.8 EGG09915.1 - 0.78 8.9 7.8 1.4 8.1 5.4 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) TMEM154 PF15102.1 EGG09916.1 - 0.0018 17.9 0.2 0.0038 16.9 0.2 1.5 1 0 0 1 1 1 1 TMEM154 protein family Rifin_STEVOR PF02009.11 EGG09916.1 - 0.0032 17.1 0.2 0.005 16.5 0.1 1.2 1 0 0 1 1 1 1 Rifin/stevor family EphA2_TM PF14575.1 EGG09916.1 - 0.0044 17.3 0.1 0.01 16.2 0.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 EGG09916.1 - 0.0058 16.8 0.9 0.0058 16.8 0.6 2.5 2 1 0 2 2 2 1 Wnt and FGF inhibitory regulator Amnionless PF14828.1 EGG09916.1 - 0.021 13.3 0.0 0.028 12.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF912 PF06024.7 EGG09916.1 - 0.037 14.0 0.3 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1191 PF06697.7 EGG09916.1 - 0.051 12.3 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Vpu PF00558.14 EGG09916.1 - 0.066 12.7 0.3 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 Vpu protein PgaD PF13994.1 EGG09916.1 - 0.082 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 PgaD-like protein VMA21 PF09446.5 EGG09916.1 - 0.2 11.5 6.1 0.047 13.6 1.9 1.6 2 0 0 2 2 1 0 VMA21-like domain Ctr PF04145.10 EGG09916.1 - 0.46 10.5 1.9 0.66 10.0 0.3 2.1 2 1 0 2 2 2 0 Ctr copper transporter family PAP_assoc PF03828.14 EGG09918.1 - 2.5e-17 62.5 0.1 2.5e-17 62.5 0.1 2.8 3 0 0 3 3 3 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EGG09918.1 - 1.5e-09 38.0 0.6 6.8e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 Nucleotidyltransferase domain DUF1515 PF07439.6 EGG09918.1 - 0.13 12.1 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Glyco_hydro_88 PF07470.8 EGG09920.1 - 4.9e-14 52.1 2.9 7.5e-14 51.5 2.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DEAD PF00270.24 EGG09921.1 - 1e-29 103.1 0.0 2e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG09921.1 - 5.5e-23 80.6 0.0 6.2e-22 77.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG09921.1 - 0.00013 21.8 0.0 0.0003 20.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EGG09921.1 - 0.038 13.9 0.0 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain DsrH PF04077.7 EGG09921.1 - 0.056 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 DsrH like protein AAA_22 PF13401.1 EGG09921.1 - 0.13 12.3 0.1 16 5.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain Hydantoinase_A PF01968.13 EGG09922.1 - 1.3e-88 296.8 1.0 3.3e-88 295.5 0.0 2.0 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGG09922.1 - 1e-56 191.2 0.3 1e-53 181.4 0.0 2.7 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region PCI_Csn8 PF10075.4 EGG09922.1 - 0.2 11.4 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Methyltransf_2 PF00891.13 EGG09924.1 - 1.3e-14 54.0 0.0 8e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase Dimerisation PF08100.6 EGG09924.1 - 0.0043 16.8 0.1 0.023 14.5 0.0 2.4 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_18 PF12847.2 EGG09924.1 - 0.014 15.9 0.0 0.24 11.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain DUF2393 PF09624.5 EGG09924.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) MTS PF05175.9 EGG09924.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Asp PF00026.18 EGG09925.1 - 7.6e-53 179.8 2.2 1.1e-52 179.2 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG09925.1 - 3.5e-09 36.8 0.6 2e-08 34.3 0.1 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EGG09925.1 - 0.00057 19.4 0.0 0.00096 18.7 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EGG09925.1 - 0.015 15.7 0.1 0.77 10.3 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease PDCD2_C PF04194.8 EGG09926.1 - 8.5e-27 93.7 0.1 8.5e-27 93.7 0.1 1.7 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain SAGA-Tad1 PF12767.2 EGG09929.1 - 1.1e-43 149.7 3.6 1.1e-43 149.7 2.5 3.3 2 1 2 4 4 4 1 Transcriptional regulator of RNA polII, SAGA, subunit NUMOD1 PF07453.8 EGG09931.1 - 0.31 10.9 4.5 0.5 10.3 0.0 3.2 4 0 0 4 4 4 0 NUMOD1 domain tRNA_int_endo PF01974.12 EGG09932.1 - 2.4e-09 36.8 0.0 5.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Tyr_Deacylase PF02580.11 EGG09933.1 - 1.7e-45 154.5 0.0 3.5e-45 153.5 0.0 1.5 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DDT PF02791.12 EGG09933.1 - 0.12 12.2 0.1 0.37 10.5 0.0 1.8 1 1 0 1 1 1 0 DDT domain GLTP PF08718.6 EGG09934.1 - 2.8e-42 144.2 0.0 4.2e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) L31 PF09784.4 EGG09935.1 - 2.3e-33 114.3 0.2 2.5e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Glyco_hydro_18 PF00704.23 EGG09936.1 - 1.4e-55 189.1 0.1 3.6e-55 187.7 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 EGG09936.1 - 0.0037 16.4 0.0 0.0094 15.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Aminotran_1_2 PF00155.16 EGG09938.1 - 0.00025 20.0 0.0 0.0007 18.6 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EGG09938.1 - 0.0016 17.0 0.0 1.1 7.6 0.0 2.2 2 0 0 2 2 2 2 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.16 EGG09939.1 - 2e-22 79.6 0.0 2.5e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EGG09939.1 - 2.6e-12 46.0 0.0 3.4e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DUF4375 PF14300.1 EGG09939.1 - 0.054 13.4 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) HMG_box PF00505.14 EGG09941.1 - 0.013 15.7 0.1 0.2 11.9 0.0 2.6 2 0 0 2 2 2 0 HMG (high mobility group) box OTU PF02338.14 EGG09943.1 - 3.4e-11 43.7 0.0 6.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.3 EGG09943.1 - 6.9e-05 23.0 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-C2H2_2 PF12756.2 EGG09943.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF3275 PF11679.3 EGG09943.1 - 0.45 10.1 2.4 4 7.0 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Ras PF00071.17 EGG09944.1 - 2.5e-53 179.7 0.0 2.8e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG09944.1 - 5.3e-16 59.1 0.0 7.5e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG09944.1 - 9.8e-07 28.1 0.0 1.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family OTU PF02338.14 EGG09945.1 - 0.0085 16.6 0.0 0.021 15.4 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease DBD_Tnp_Mut PF03108.10 EGG09945.1 - 0.076 12.5 1.9 0.35 10.4 1.3 2.0 1 1 0 1 1 1 0 MuDR family transposase Peptidase_C65 PF10275.4 EGG09945.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase C65 Otubain PRT_C PF08372.5 EGG09946.1 - 0.068 12.6 0.1 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DUF2935 PF11155.3 EGG09946.1 - 0.086 12.9 0.1 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) NYN_YacP PF05991.6 EGG09947.1 - 0.46 10.2 2.5 0.31 10.7 0.7 1.5 2 0 0 2 2 2 0 YacP-like NYN domain PUF PF00806.14 EGG09949.1 - 1.7e-21 74.3 0.2 6.5e-05 22.2 0.1 5.6 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EGG09949.1 - 1.3e-15 56.7 0.0 1.4e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG09949.1 - 2.6e-14 52.9 0.0 8.9e-06 25.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG09949.1 - 1.6e-05 24.6 0.0 0.0016 18.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MdcG PF10620.4 EGG09949.1 - 0.055 13.0 0.2 0.15 11.5 0.1 1.7 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG Dodecin PF07311.7 EGG09949.1 - 0.25 11.3 0.0 0.54 10.3 0.0 1.4 1 0 0 1 1 1 0 Dodecin WD40 PF00400.27 EGG09950.1 - 2.3e-13 49.4 12.9 1.3e-07 31.1 0.2 5.0 4 1 0 4 4 4 3 WD domain, G-beta repeat PMC2NT PF08066.7 EGG09951.1 - 0.051 13.8 0.2 0.097 12.9 0.2 1.5 1 0 0 1 1 1 0 PMC2NT (NUC016) domain DUF3117 PF11314.3 EGG09953.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3117) MCM PF00493.18 EGG09955.1 - 2.5e-133 444.0 0.1 4.8e-133 443.0 0.0 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EGG09955.1 - 4.4e-23 82.0 1.2 9.7e-23 80.9 0.4 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGG09955.1 - 1.8e-07 30.5 0.0 1.4e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGG09955.1 - 5.7e-07 29.3 0.0 2e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EGG09955.1 - 0.0046 17.3 0.4 0.012 16.0 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGG09955.1 - 0.017 14.7 0.0 0.059 12.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CaM-KIIN PF15170.1 EGG09955.1 - 0.034 14.1 1.7 0.38 10.7 1.6 2.2 2 0 0 2 2 2 0 Calcium/calmodulin-dependent protein kinase II inhibitor Sigma54_activat PF00158.21 EGG09955.1 - 0.058 12.8 0.0 0.66 9.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4611 PF15387.1 EGG09955.1 - 8.3 6.6 10.0 15 5.7 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) PCI PF01399.22 EGG09959.1 - 3.8e-05 23.9 0.3 3.8e-05 23.9 0.2 2.4 3 0 0 3 3 3 1 PCI domain PBP1_TM PF14812.1 EGG09960.1 - 6.5 7.1 11.2 1.9 8.8 5.3 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cu_bind_like PF02298.12 EGG09962.1 - 0.00021 21.0 0.0 0.8 9.5 0.0 2.4 2 0 0 2 2 2 2 Plastocyanin-like domain HALZ PF02183.13 EGG09963.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 EGG09965.1 - 0.0024 17.6 7.2 0.0054 16.5 5.0 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus NADPH_Ox PF08414.5 EGG09965.1 - 0.013 15.5 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase Med29 PF11568.3 EGG09965.1 - 0.04 13.9 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 29 SF-assemblin PF06705.6 EGG09965.1 - 0.051 12.7 1.1 0.085 11.9 0.8 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin LRR_5 PF13306.1 EGG09966.1 - 0.01 15.5 2.0 0.015 14.9 1.2 1.3 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EGG09966.1 - 0.12 12.1 4.7 0.11 12.2 1.2 2.4 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 EGG09966.1 - 0.18 11.4 0.9 3.3 7.4 0.2 3.0 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) Vps5 PF09325.5 EGG09968.1 - 0.0084 15.3 2.1 0.014 14.6 1.4 1.2 1 0 0 1 1 1 1 Vps5 C terminal like Phasin PF05597.6 EGG09968.1 - 0.014 15.1 3.3 1.5 8.5 1.0 2.8 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Reo_sigmaC PF04582.7 EGG09968.1 - 0.019 14.1 4.1 0.031 13.4 2.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 EGG09968.1 - 0.057 13.5 1.7 0.13 12.3 1.2 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 EGG09968.1 - 0.066 13.4 12.2 0.048 13.9 3.5 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein MbeD_MobD PF04899.7 EGG09968.1 - 0.082 12.8 1.0 6.6 6.7 0.2 2.7 1 1 1 2 2 2 0 MbeD/MobD like MCPsignal PF00015.16 EGG09968.1 - 0.088 12.3 3.5 0.17 11.4 2.4 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LPP PF04728.8 EGG09968.1 - 0.11 12.3 10.5 1.3 8.8 1.2 2.6 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Laminin_II PF06009.7 EGG09968.1 - 0.11 12.1 4.8 2.1 8.0 2.7 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 EGG09968.1 - 0.14 11.9 1.2 0.36 10.6 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ank_2 PF12796.2 EGG09969.1 - 2.2e-10 40.7 0.0 4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGG09969.1 - 2.7e-08 33.2 0.0 5.7e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 EGG09969.1 - 2.3e-07 30.8 0.1 4.7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGG09969.1 - 2.3e-07 31.1 0.0 1.6e-06 28.4 0.0 2.1 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGG09969.1 - 1.3e-06 28.0 0.0 6.1e-06 25.9 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeat Methyltransf_18 PF12847.2 EGG09969.1 - 0.041 14.4 0.0 0.11 13.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Glyco_transf_21 PF13506.1 EGG09971.1 - 4.6e-21 74.8 0.0 3e-17 62.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EGG09971.1 - 1.7e-15 57.4 0.0 2.4e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGG09971.1 - 0.00082 19.1 0.2 0.00082 19.1 0.1 1.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EGG09971.1 - 0.0019 17.9 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 RRM_1 PF00076.17 EGG09973.1 - 1.8e-35 120.3 0.0 6.1e-19 67.4 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG09973.1 - 1.3e-18 66.7 0.0 2.7e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG09973.1 - 2.1e-14 53.1 0.1 8.3e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EGG09973.1 - 0.01 15.2 0.1 0.28 10.6 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 EGG09973.1 - 0.023 14.4 0.0 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 DUF3176 PF11374.3 EGG09974.1 - 0.053 13.3 0.3 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3176) Aldedh PF00171.17 EGG09976.1 - 4.4e-182 605.5 0.0 5e-182 605.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Baculo_PEP_N PF04512.7 EGG09978.1 - 0.099 12.6 0.0 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, N terminus Iron_permease PF04120.7 EGG09979.1 - 0.71 9.4 2.7 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 Low affinity iron permease V_ATPase_I PF01496.14 EGG09981.1 - 4.2e-272 904.4 0.0 5.3e-272 904.1 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4600 PF15372.1 EGG09981.1 - 0.097 12.8 0.3 0.77 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) RRM_1 PF00076.17 EGG09982.1 - 0.0014 18.2 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG09982.1 - 0.0061 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FYVE PF01363.16 EGG09982.1 - 0.0082 16.0 1.7 0.0084 15.9 0.2 1.8 2 0 0 2 2 2 1 FYVE zinc finger zf-CCCH PF00642.19 EGG09982.1 - 0.035 13.7 2.6 0.035 13.7 1.8 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGG09982.1 - 0.06 13.3 1.7 0.06 13.3 1.2 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type GRIP PF01465.15 EGG09983.1 - 6.7e-07 28.7 0.1 2.1e-06 27.1 0.1 1.9 1 0 0 1 1 1 1 GRIP domain YlqD PF11068.3 EGG09983.1 - 0.00037 20.5 11.4 0.00037 20.5 7.9 6.0 2 2 3 5 5 5 2 YlqD protein AAA_13 PF13166.1 EGG09983.1 - 0.0023 16.4 22.9 0.0023 16.4 15.9 2.6 1 1 1 2 2 2 1 AAA domain Filament PF00038.16 EGG09983.1 - 0.06 12.8 70.5 0.021 14.3 12.5 4.0 1 1 3 4 4 4 0 Intermediate filament protein IncA PF04156.9 EGG09983.1 - 0.29 10.7 79.0 0.93 9.0 16.0 3.8 1 1 2 3 3 3 0 IncA protein DUF3584 PF12128.3 EGG09983.1 - 1.4 6.1 69.5 2.5 5.3 21.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 EGG09983.1 - 1.5 8.5 73.7 0.2 11.4 8.5 5.0 1 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein WD40 PF00400.27 EGG09984.1 - 2.8e-42 141.0 17.1 5.7e-10 38.6 0.4 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGG09984.1 - 0.00021 21.0 0.2 0.5 10.0 0.0 3.4 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 EGG09984.1 - 0.0069 15.8 4.1 0.054 12.8 0.1 2.7 2 1 1 3 3 3 2 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EGG09984.1 - 0.0086 15.7 0.4 11 5.7 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF4221 PF13970.1 EGG09984.1 - 0.021 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) HMG_box PF00505.14 EGG09985.1 - 0.00061 19.9 0.1 0.00061 19.9 0.0 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGG09985.1 - 0.0032 17.7 1.1 0.0054 17.0 0.0 1.9 2 0 0 2 2 2 1 HMG-box domain Carot_N PF09150.5 EGG09985.1 - 0.041 13.5 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal UPF0181 PF03701.9 EGG09985.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) zf-CCHC_4 PF14392.1 EGG09987.1 - 0.013 15.1 0.6 0.024 14.3 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EGG09987.1 - 0.016 15.1 2.0 0.031 14.2 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle WRC PF08879.5 EGG09988.1 - 0.025 14.2 0.8 0.036 13.7 0.5 1.2 1 0 0 1 1 1 0 WRC CENP-B_N PF04218.8 EGG09988.1 - 0.055 12.9 0.6 0.18 11.2 0.1 2.0 1 1 1 2 2 2 0 CENP-B N-terminal DNA-binding domain Herpes_BBRF1 PF04793.7 EGG09988.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 BRRF1-like protein YjcQ PF09639.5 EGG09991.1 - 0.05 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 YjcQ protein Carbpep_Y_N PF05388.6 EGG09995.1 - 0.031 14.4 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide NAD_binding_4 PF07993.7 EGG09997.1 - 0.00034 19.6 0.2 0.001 18.0 0.0 1.6 1 1 1 2 2 2 1 Male sterility protein DUF1793 PF08760.6 EGG10000.1 - 4.8e-12 46.0 0.0 5.8e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GATase_2 PF00310.16 EGG10006.1 - 1.9e-25 89.3 0.2 5.3e-19 68.1 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGG10006.1 - 1.7e-14 53.9 0.0 3.7e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EGG10006.1 - 6.1e-12 45.3 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EGG10006.1 - 8.5e-12 44.8 0.1 1.6e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EGG10006.1 - 4.1e-07 28.9 0.0 9.2e-07 27.8 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferases class-II AP_endonuc_2 PF01261.19 EGG10006.1 - 0.013 14.8 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel SURF1 PF02104.10 EGG10007.1 - 1.2e-58 198.4 0.0 1.6e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 SURF1 family ADK PF00406.17 EGG10009.1 - 1.3e-58 197.1 0.0 1.9e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EGG10009.1 - 1.9e-15 56.2 0.0 3.9e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EGG10009.1 - 4.7e-05 24.1 0.0 9.2e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGG10009.1 - 0.0013 17.8 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EGG10009.1 - 0.0051 16.6 0.0 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGG10009.1 - 0.039 14.1 0.3 2.1 8.4 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.1 EGG10009.1 - 0.081 13.2 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Paf67 PF10255.4 EGG10010.1 - 4e-144 480.4 0.0 5e-144 480.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Apc3 PF12895.2 EGG10010.1 - 0.023 14.8 2.3 0.31 11.2 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EGG10010.1 - 0.091 12.7 0.6 0.43 10.6 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MCPVI PF02993.9 EGG10011.1 - 0.61 10.2 3.8 0.72 9.9 2.6 1.1 1 0 0 1 1 1 0 Minor capsid protein VI HTH_38 PF13936.1 EGG10014.1 - 0.024 14.1 0.0 5 6.7 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain F-box-like_2 PF13013.1 EGG10015.1 - 0.007 16.0 2.9 3.8 7.2 0.2 3.6 4 0 0 4 4 4 2 F-box-like domain LRR_4 PF12799.2 EGG10015.1 - 1.1 8.9 11.9 1.3 8.7 0.2 5.5 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Shugoshin_C PF07557.6 EGG10016.1 - 9.9e-09 34.5 6.2 9.9e-09 34.5 4.3 2.7 3 0 0 3 3 3 1 Shugoshin C terminus Shugoshin_N PF07558.6 EGG10016.1 - 3.4e-05 23.4 7.5 0.00019 21.0 5.2 2.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DEAD PF00270.24 EGG10017.1 - 3.5e-34 117.7 0.0 6.8e-34 116.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG10017.1 - 4.5e-19 68.0 0.3 1.1e-09 38.0 0.2 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EGG10017.1 - 8.5e-05 22.4 0.0 0.00049 19.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2660 PF10859.3 EGG10018.1 - 0.13 12.5 0.9 0.16 12.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) G6PD_C PF02781.11 EGG10020.1 - 2.5e-126 420.4 0.0 3.9e-126 419.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EGG10020.1 - 2e-60 204.1 0.0 5.7e-60 202.6 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF1399 PF07173.7 EGG10022.1 - 3.6e-19 69.3 0.4 7.3e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) RRM_1 PF00076.17 EGG10024.1 - 3.1e-08 33.1 0.0 8.7e-08 31.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3231 PF11553.3 EGG10024.1 - 0.0011 18.4 0.2 0.0019 17.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3231) RRM_6 PF14259.1 EGG10024.1 - 0.0016 18.3 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGG10024.1 - 0.0056 16.5 0.3 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif DNA_Packaging PF11053.3 EGG10024.1 - 0.28 10.7 1.8 0.3 10.7 0.0 1.9 2 1 1 3 3 3 0 Terminase DNA packaging enzyme CM_2 PF01817.16 EGG10025.1 - 1.6e-08 34.4 1.0 7.1e-08 32.4 0.1 2.4 2 1 0 2 2 2 1 Chorismate mutase type II RNB PF00773.14 EGG10026.1 - 2.6e-98 329.2 0.0 4e-98 328.7 0.0 1.3 1 0 0 1 1 1 1 RNB domain Ank_4 PF13637.1 EGG10027.1 - 0.00092 19.6 0.0 6.2 7.4 0.0 4.7 2 2 3 5 5 5 1 Ankyrin repeats (many copies) LNS2 PF08235.8 EGG10027.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Ank_3 PF13606.1 EGG10027.1 - 0.098 12.9 0.0 1.8e+02 2.8 0.0 4.5 5 1 0 5 5 5 0 Ankyrin repeat PGM_PMM_I PF02878.11 EGG10028.1 - 1.3e-36 125.1 0.1 1.9e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EGG10028.1 - 2.3e-25 88.8 0.0 4.1e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EGG10028.1 - 3.8e-16 59.2 0.0 1.2e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGG10028.1 - 2.6e-10 40.1 0.0 6.2e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1793 PF08760.6 EGG10030.1 - 6.6e-57 192.0 0.0 1.1e-56 191.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) SPX PF03105.14 EGG10032.1 - 0.00017 21.4 8.2 0.00019 21.3 5.7 1.1 1 0 0 1 1 1 1 SPX domain Synaptobrevin PF00957.16 EGG10032.1 - 0.0015 18.0 8.0 0.21 11.2 1.1 2.4 1 1 1 2 2 2 2 Synaptobrevin SAPS PF04499.10 EGG10032.1 - 0.0061 15.2 5.3 0.0065 15.1 3.7 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein CAF-1_p150 PF11600.3 EGG10032.1 - 0.0063 15.9 45.9 0.008 15.5 31.8 1.0 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal LMBR1 PF04791.11 EGG10032.1 - 0.011 14.3 2.9 0.0098 14.5 2.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein N6_N4_Mtase PF01555.13 EGG10032.1 - 0.031 13.7 6.8 0.041 13.3 4.7 1.3 1 0 0 1 1 1 0 DNA methylase Chordopox_A33R PF05966.7 EGG10032.1 - 0.099 11.4 1.8 0.11 11.2 0.7 1.5 1 1 0 1 1 1 0 Chordopoxvirus A33R protein Borrelia_P83 PF05262.6 EGG10032.1 - 0.57 8.3 25.1 0.71 8.0 17.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ycf1 PF05758.7 EGG10032.1 - 0.65 7.6 17.5 0.78 7.3 12.1 1.1 1 0 0 1 1 1 0 Ycf1 Fmp27_WPPW PF10359.4 EGG10032.1 - 0.82 8.0 23.8 1 7.6 16.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Suf PF05843.9 EGG10032.1 - 1.3 8.6 10.4 1.6 8.4 7.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Allexi_40kDa PF05549.6 EGG10032.1 - 1.7 7.8 15.6 2.5 7.3 10.8 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein EMP24_GP25L PF01105.19 EGG10032.1 - 1.8 8.2 10.3 3.1 7.4 7.2 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF948 PF06103.6 EGG10032.1 - 2.3 8.1 4.9 12 5.8 0.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SRP-alpha_N PF04086.8 EGG10032.1 - 4.3 6.6 23.1 5.3 6.3 16.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF1510 PF07423.6 EGG10032.1 - 9.3 5.5 27.6 19 4.5 19.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) Cu-oxidase_3 PF07732.10 EGG10034.1 - 8.5e-47 157.7 3.6 1e-43 147.7 0.7 3.4 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG10034.1 - 1.6e-35 121.5 1.0 1.2e-29 102.6 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EGG10034.1 - 7.3e-26 90.9 0.1 2.4e-23 82.7 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase E1_DerP2_DerF2 PF02221.10 EGG10034.1 - 0.075 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 ML domain DASH_Dam1 PF08653.5 EGG10035.1 - 9e-15 54.1 0.1 1.5e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 gerPA PF10676.4 EGG10035.1 - 0.19 11.5 0.6 0.51 10.2 0.1 1.8 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF DUF2638 PF10937.3 EGG10035.1 - 0.31 12.0 5.5 0.078 14.0 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) DFP PF04127.10 EGG10036.1 - 0.072 12.7 0.3 0.072 12.7 0.2 1.8 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein vMSA PF00695.14 EGG10036.1 - 0.12 11.5 2.8 0.18 11.0 2.0 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF2072 PF09845.4 EGG10036.1 - 7 6.5 7.7 54 3.7 5.3 2.4 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Peroxidase_2 PF01328.12 EGG10037.1 - 1.6e-10 40.1 0.0 4.8e-10 38.6 0.0 1.8 1 1 1 2 2 2 1 Peroxidase, family 2 CTP_transf_2 PF01467.21 EGG10038.1 - 1.3e-25 90.3 0.0 1.6e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Chitin_synth_1 PF01644.12 EGG10040.1 - 1.2e-89 298.3 0.2 1.9e-89 297.6 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGG10040.1 - 8.3e-33 111.9 1.7 1.8e-32 110.8 0.4 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGG10040.1 - 4.3e-23 81.5 0.7 2.1e-18 66.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EGG10040.1 - 1.5e-07 31.3 0.9 1.5e-07 31.3 0.6 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGG10040.1 - 0.00012 21.9 0.0 0.00034 20.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Aldedh PF00171.17 EGG10044.1 - 2.7e-158 527.1 0.0 3.3e-158 526.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNA_pol_Rpb4 PF03874.11 EGG10045.1 - 0.11 12.5 0.1 22 5.1 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb4 Pyr_redox_3 PF13738.1 EGG10047.1 - 3.2e-15 56.7 0.0 9.2e-13 48.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGG10047.1 - 7.7e-12 44.1 0.5 1.7e-10 39.7 0.2 2.8 1 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGG10047.1 - 5.2e-09 36.0 0.4 5.9e-08 32.6 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGG10047.1 - 1.1e-06 27.8 3.2 1.2e-06 27.7 0.0 2.3 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGG10047.1 - 2.6e-06 27.4 0.2 0.0026 17.6 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGG10047.1 - 3.1e-05 23.0 0.4 0.00044 19.2 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGG10047.1 - 6.5e-05 22.7 1.5 0.00027 20.7 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EGG10047.1 - 0.00011 21.4 1.6 0.017 14.2 0.0 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGG10047.1 - 0.00014 21.0 1.9 0.075 12.1 0.3 2.8 3 0 0 3 3 3 2 Thi4 family 3HCDH_N PF02737.13 EGG10047.1 - 0.00042 20.0 0.5 0.00042 20.0 0.4 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EGG10047.1 - 0.0069 15.2 0.3 0.0069 15.2 0.2 2.3 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 EGG10047.1 - 0.0083 16.5 10.0 0.099 13.0 0.2 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EGG10047.1 - 0.052 12.9 0.7 0.096 12.0 0.5 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EGG10047.1 - 0.099 11.0 6.3 0.051 12.0 0.7 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_2 PF03446.10 EGG10047.1 - 0.15 11.9 0.1 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EGG10047.1 - 0.24 10.9 2.0 4.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EGG10047.1 - 0.24 11.4 0.2 77 3.3 0.1 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EGG10047.1 - 1.9 7.2 6.5 0.39 9.5 0.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A YlqD PF11068.3 EGG10048.1 - 3.7 7.6 14.2 0.51 10.3 6.1 2.1 2 0 0 2 2 2 0 YlqD protein IncA PF04156.9 EGG10048.1 - 6.7 6.2 11.3 14 5.1 7.8 1.5 1 0 0 1 1 1 0 IncA protein DUF1804 PF08822.6 EGG10049.1 - 0.087 12.5 0.2 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Uso1_p115_C PF04871.8 EGG10050.1 - 0.34 10.8 1.7 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-HC5HC2H PF13771.1 EGG10052.1 - 0.013 15.6 1.6 0.027 14.6 1.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain HECA PF15353.1 EGG10052.1 - 0.043 13.5 4.8 0.17 11.6 0.5 2.4 1 1 1 2 2 2 0 Headcase protein family homologue zf-HC5HC2H_2 PF13832.1 EGG10052.1 - 0.049 13.6 2.5 0.092 12.7 1.7 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-PHD-like PF15446.1 EGG10052.1 - 0.089 12.0 4.1 0.14 11.4 2.8 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain YjfB_motility PF14070.1 EGG10052.1 - 0.29 10.9 2.2 8.1 6.3 0.1 2.3 2 0 0 2 2 2 0 Putative motility protein zf-C2H2 PF00096.21 EGG10052.1 - 0.52 10.7 0.2 0.52 10.7 0.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG10052.1 - 0.78 10.2 5.3 6.6 7.3 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Menin PF05053.8 EGG10053.1 - 4.4 5.3 8.7 5 5.1 6.1 1.1 1 0 0 1 1 1 0 Menin SOG2 PF10428.4 EGG10053.1 - 8.4 4.9 8.1 9.8 4.7 5.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Ctr PF04145.10 EGG10054.1 - 2.7e-26 92.3 0.1 3.5e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family UCR_UQCRX_QCR9 PF05365.7 EGG10054.1 - 0.19 11.3 1.6 0.35 10.5 1.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4386 PF14329.1 EGG10054.1 - 0.66 9.4 6.4 0.25 10.7 2.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) F-box PF00646.28 EGG10055.1 - 0.038 13.6 1.1 0.099 12.3 0.7 1.8 1 0 0 1 1 1 0 F-box domain Vac14_Fig4_bd PF11916.3 EGG10056.1 - 1.5e-71 239.3 4.3 1.5e-71 239.3 3.0 1.8 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EGG10056.1 - 7.7e-38 128.8 0.0 2.3e-35 120.8 0.0 3.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EGG10056.1 - 4.2e-09 35.7 0.1 0.0018 18.1 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 EGG10056.1 - 3.6e-06 27.1 0.5 0.28 11.4 0.0 4.2 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EGG10056.1 - 0.00051 20.4 2.5 1.3 9.6 0.0 5.3 5 1 1 6 6 6 1 HEAT-like repeat RecO_C PF02565.10 EGG10056.1 - 0.1 12.4 7.3 0.37 10.6 0.1 3.5 4 0 0 4 4 4 0 Recombination protein O C terminal ParcG PF10274.4 EGG10056.1 - 0.16 11.8 1.6 5.4 6.8 0.0 3.3 4 0 0 4 4 4 0 Parkin co-regulated protein VIT1 PF01988.14 EGG10060.1 - 1.4 8.3 11.5 0.5 9.8 2.4 2.6 2 0 0 2 2 2 0 VIT family Clathrin_lg_ch PF01086.12 EGG10062.1 - 4.7e-49 167.3 6.2 7.6e-49 166.6 4.3 1.3 1 1 0 1 1 1 1 Clathrin light chain TcpF PF06340.6 EGG10062.1 - 0.02 14.0 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F DUF4407 PF14362.1 EGG10062.1 - 0.39 9.6 6.1 0.56 9.1 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ham1p_like PF01725.11 EGG10064.1 - 9.1e-52 175.1 0.0 1.8e-51 174.2 0.0 1.4 1 1 0 1 1 1 1 Ham1 family ArsA_ATPase PF02374.10 EGG10064.1 - 0.0061 15.6 0.1 0.0091 15.0 0.1 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase RCC1 PF00415.13 EGG10065.1 - 8.6e-22 77.0 0.7 0.0074 16.4 0.0 8.5 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGG10065.1 - 1.4e-14 53.1 8.1 1.8e-08 33.7 0.5 5.7 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat ThiG PF05690.9 EGG10065.1 - 0.05 12.6 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Pterin_bind PF00809.17 EGG10066.1 - 7.3e-70 234.5 0.0 2.2e-69 233.0 0.0 1.8 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 EGG10066.1 - 2.1e-34 118.0 0.0 5.4e-34 116.6 0.0 1.8 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 EGG10066.1 - 7.8e-20 71.1 0.0 2e-18 66.5 0.0 2.4 2 0 0 2 2 2 1 Dihydroneopterin aldolase HIG_1_N PF04588.8 EGG10066.1 - 0.95 9.2 2.8 0.46 10.2 0.1 1.9 2 0 0 2 2 2 0 Hypoxia induced protein conserved region Ceramidase PF05875.7 EGG10067.1 - 1.8e-81 273.1 4.4 2.1e-81 272.9 3.0 1.0 1 0 0 1 1 1 1 Ceramidase HlyIII PF03006.15 EGG10067.1 - 0.0088 15.4 7.9 0.023 14.1 5.2 1.8 1 1 1 2 2 2 1 Haemolysin-III related TCR_zetazeta PF11628.3 EGG10067.1 - 0.059 12.8 0.6 0.059 12.8 0.4 1.8 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain 7TMR-DISM_7TM PF07695.6 EGG10067.1 - 1.5 8.4 9.6 0.15 11.7 3.1 1.9 2 0 0 2 2 2 0 7TM diverse intracellular signalling CPSase_L_D2 PF02786.12 EGG10068.1 - 2.2e-110 366.9 0.1 4.5e-84 280.9 0.0 2.5 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EGG10068.1 - 4.3e-40 136.3 0.1 1.1e-39 135.0 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EGG10068.1 - 4.4e-38 129.7 0.0 6.6e-19 68.0 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EGG10068.1 - 1.5e-35 122.6 0.5 1e-19 71.0 0.0 3.1 4 0 0 4 4 4 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGG10068.1 - 1.3e-25 89.8 0.0 3.3e-15 55.6 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EGG10068.1 - 1.2e-16 60.5 0.0 8e-08 31.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGG10068.1 - 1.2e-13 50.9 0.1 3.8e-06 26.4 0.0 3.4 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EGG10068.1 - 4.4e-08 32.8 0.0 0.00031 20.2 0.0 3.1 2 1 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 EGG10068.1 - 0.00012 21.4 0.0 0.22 10.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 EGG10068.1 - 0.0021 17.9 0.0 0.041 13.8 0.0 3.0 1 1 0 1 1 1 1 MGS-like domain Peptidase_M17_N PF02789.12 EGG10068.1 - 0.031 14.0 0.1 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain NCD3G PF07562.9 EGG10069.1 - 3.3 7.5 9.2 0.74 9.5 0.1 2.9 3 0 0 3 3 3 0 Nine Cysteines Domain of family 3 GPCR Sel1 PF08238.7 EGG10070.1 - 1.1e-30 105.2 29.1 0.00024 21.6 0.0 11.7 11 1 0 11 11 11 8 Sel1 repeat TPR_11 PF13414.1 EGG10070.1 - 1.5e-05 24.5 9.0 0.00051 19.6 0.0 5.3 6 0 0 6 6 6 2 TPR repeat TPR_1 PF00515.23 EGG10070.1 - 0.0005 19.5 5.1 0.71 9.5 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGG10070.1 - 0.0017 18.1 5.8 0.78 9.8 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGG10070.1 - 0.012 15.4 8.1 0.41 10.6 0.0 5.5 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGG10070.1 - 0.033 14.8 8.0 0.091 13.4 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_S15 PF00312.17 EGG10071.1 - 9.2e-08 31.7 0.2 9.2e-08 31.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 Spore_coat_CotO PF14153.1 EGG10075.1 - 0.36 10.2 20.3 1.3 8.4 7.0 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Rhabdo_M2 PF04785.7 EGG10076.1 - 0.062 12.3 0.1 0.082 11.9 0.1 1.2 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 Abhydrolase_3 PF07859.8 EGG10077.1 - 6.7e-05 22.5 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold APG5 PF04106.7 EGG10078.1 - 1.3e-50 171.6 0.0 1.7e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 UBN2_2 PF14227.1 EGG10079.1 - 4.1e-08 32.8 0.0 6.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGG10079.1 - 8.3e-06 25.5 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type ADH_N PF08240.7 EGG10083.1 - 5.9e-25 87.1 1.4 1.3e-24 86.0 0.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGG10083.1 - 1.2e-14 53.9 0.0 2e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TUG-UBL1 PF11470.3 EGG10083.1 - 0.05 13.5 0.0 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 GLUT4 regulating protein TUG ADH_zinc_N_2 PF13602.1 EGG10083.1 - 0.07 14.0 0.0 0.12 13.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1918 PF08940.6 EGG10083.1 - 1.1 8.6 4.1 0.3 10.4 0.4 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) 5-FTHF_cyc-lig PF01812.15 EGG10084.1 - 1e-37 129.7 0.0 1.1e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Retro_M PF02813.9 EGG10084.1 - 0.016 15.3 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 Retroviral M domain Leo1 PF04004.8 EGG10085.1 - 1.4e-42 145.3 1.1 1.4e-42 145.3 0.7 3.4 3 1 1 4 4 4 1 Leo1-like protein Pkinase PF00069.20 EGG10087.1 - 1.2e-61 208.1 0.4 1.4e-61 207.9 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG10087.1 - 3.7e-36 124.5 0.0 4.7e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG10087.1 - 0.00032 19.7 0.0 0.00049 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGG10087.1 - 0.00036 20.3 0.0 0.011 15.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGG10087.1 - 0.0012 17.7 0.7 0.0042 15.9 0.0 1.9 1 1 1 2 2 2 1 Seadornavirus VP7 RIO1 PF01163.17 EGG10087.1 - 0.0024 17.2 0.7 0.45 9.8 0.0 2.2 1 1 1 2 2 2 2 RIO1 family MutS_IV PF05190.13 EGG10087.1 - 0.15 12.2 0.1 0.15 12.2 0.0 1.9 3 0 0 3 3 3 0 MutS family domain IV PK PF00224.16 EGG10088.1 - 8.1e-157 521.2 0.7 1e-156 520.9 0.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EGG10088.1 - 3e-30 104.1 0.1 6.5e-30 103.0 0.1 1.5 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EGG10088.1 - 0.01 14.7 0.6 0.029 13.2 0.4 1.7 1 1 1 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family zf-RING_2 PF13639.1 EGG10091.1 - 4.2e-06 26.4 6.2 9.4e-06 25.3 4.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGG10091.1 - 6e-06 25.8 8.1 1.6e-05 24.5 5.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGG10091.1 - 0.00017 21.5 8.3 0.00043 20.2 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGG10091.1 - 0.00025 20.6 2.4 0.00086 18.9 1.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EGG10091.1 - 0.00054 19.5 4.1 0.0014 18.2 2.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGG10091.1 - 0.0011 18.7 7.3 0.01 15.7 5.4 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING FYVE PF01363.16 EGG10091.1 - 0.0074 16.1 5.3 0.024 14.5 3.7 1.8 1 0 0 1 1 1 1 FYVE zinc finger DUF948 PF06103.6 EGG10091.1 - 0.0084 15.9 3.6 0.036 13.9 0.8 2.4 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.17 EGG10091.1 - 0.0086 16.0 5.1 0.0086 16.0 3.6 1.8 2 0 0 2 2 1 1 Seryl-tRNA synthetase N-terminal domain DUF3166 PF11365.3 EGG10091.1 - 0.025 15.0 3.5 49 4.4 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) RAP1 PF07218.6 EGG10091.1 - 0.028 12.5 8.9 0.036 12.1 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ten1_2 PF15490.1 EGG10091.1 - 0.043 13.4 0.2 0.36 10.4 0.2 2.2 2 0 0 2 2 2 0 Telomere-capping, CST complex subunit zf-C4H2 PF10146.4 EGG10091.1 - 0.05 13.6 4.9 0.086 12.8 3.4 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Rab5-bind PF09311.6 EGG10091.1 - 0.053 13.4 10.0 0.093 12.6 7.0 1.3 1 0 0 1 1 1 0 Rabaptin-like protein DUF342 PF03961.8 EGG10091.1 - 0.069 11.5 4.1 0.1 11.0 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) bZIP_Maf PF03131.12 EGG10091.1 - 0.081 13.2 6.8 3.5 7.9 1.7 2.7 2 0 0 2 2 2 0 bZIP Maf transcription factor V_ATPase_I PF01496.14 EGG10091.1 - 0.094 10.5 3.9 0.13 10.1 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 EGG10091.1 - 0.095 12.3 7.8 0.18 11.4 5.4 1.4 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.10 EGG10091.1 - 0.11 12.0 9.5 1.5 8.3 2.1 3.0 2 1 1 3 3 3 0 Septum formation initiator CENP-F_leu_zip PF10473.4 EGG10091.1 - 0.11 12.3 11.6 0.21 11.4 8.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EGG10091.1 - 0.13 11.2 10.6 0.21 10.6 7.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Uso1_p115_C PF04871.8 EGG10091.1 - 0.19 11.6 9.5 0.2 11.5 5.7 1.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region IncA PF04156.9 EGG10091.1 - 0.2 11.2 11.3 0.31 10.6 7.8 1.3 1 0 0 1 1 1 0 IncA protein FliT PF05400.8 EGG10091.1 - 0.3 11.4 4.9 0.68 10.3 3.4 1.6 1 0 0 1 1 1 0 Flagellar protein FliT Macoilin PF09726.4 EGG10091.1 - 0.49 8.6 13.6 0.78 7.9 9.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 EGG10091.1 - 2.1 6.5 8.9 3 6.0 6.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF904 PF06005.7 EGG10091.1 - 2.2 8.6 16.6 3.2 8.1 1.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TBPIP PF07106.8 EGG10091.1 - 3.5 7.1 11.6 4.2 6.9 5.9 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 EGG10091.1 - 6.3 6.8 12.1 7.8 6.5 1.7 3.1 1 1 2 3 3 3 0 bZIP transcription factor TMF_TATA_bd PF12325.3 EGG10091.1 - 7.1 6.3 12.7 2.9 7.6 4.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Alpha_TIF PF02232.10 EGG10093.1 - 0.023 13.5 0.6 0.038 12.7 0.4 1.3 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) Peptidase_M10_C PF08548.6 EGG10094.1 - 0.076 12.5 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal BLYB PF05289.6 EGG10095.1 - 8.3e-05 22.3 13.7 0.56 10.0 0.1 7.0 5 2 2 7 7 7 2 Borrelia hemolysin accessory protein Ub-Mut7C PF14451.1 EGG10095.1 - 0.00096 18.6 5.1 2.3 7.7 0.0 5.3 4 2 2 6 6 6 2 Mut7-C ubiquitin DUF2520 PF10728.4 EGG10095.1 - 0.4 10.1 4.8 25 4.3 0.1 4.4 2 1 2 4 4 4 0 Domain of unknown function (DUF2520) CAP_N PF01213.14 EGG10095.1 - 1.9 7.7 12.7 2.6 7.2 1.9 3.3 1 1 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF4164 PF13747.1 EGG10095.1 - 3.4 7.8 24.5 1.1 9.4 0.7 7.5 10 1 0 10 10 10 0 Domain of unknown function (DUF4164) DUF1136 PF06582.7 EGG10095.1 - 7.8 6.3 12.2 1.5e+02 2.2 0.0 6.4 7 0 0 7 7 7 0 Repeat of unknown function (DUF1136) Aldo_ket_red PF00248.16 EGG10099.1 - 9e-48 162.5 0.0 1.1e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family IL3 PF02059.10 EGG10101.1 - 0.047 13.6 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Interleukin-3 PTS_IIA PF02255.11 EGG10102.1 - 0.028 14.3 0.3 0.028 14.3 0.2 1.5 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF4398 PF14346.1 EGG10102.1 - 0.03 14.3 0.7 0.03 14.3 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) BMF PF15185.1 EGG10102.1 - 0.066 12.5 5.9 0.084 12.1 4.1 1.3 1 1 0 1 1 1 0 Bcl-2-modifying factor, apoptosis Cwf_Cwc_15 PF04889.7 EGG10102.1 - 0.28 10.8 14.3 0.33 10.6 9.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CcmH PF03918.9 EGG10103.1 - 0.014 14.3 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Elf1 PF05129.8 EGG10103.1 - 0.11 12.2 1.8 0.13 11.9 1.3 1.1 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-4CXXC_R1 PF10497.4 EGG10103.1 - 0.3 11.2 2.9 0.41 10.8 2.0 1.3 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Ifi-6-16 PF06140.8 EGG10105.1 - 1e-06 28.4 11.8 1.4e-06 27.9 8.1 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family TFIID_30kDa PF03540.8 EGG10106.1 - 2.2e-24 85.0 0.1 4.3e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 EGG10106.1 - 0.0021 17.7 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 1 Bromodomain associated TFIIA PF03153.8 EGG10106.1 - 2.3 8.0 8.4 3.5 7.4 5.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EGG10106.1 - 6.2 6.1 20.1 9.5 5.4 13.9 1.2 1 0 0 1 1 1 0 Vta1 like zf-MYND PF01753.13 EGG10108.1 - 8.3 6.3 8.0 26 4.8 0.1 2.3 2 0 0 2 2 2 0 MYND finger Hydrolase_6 PF13344.1 EGG10109.1 - 8.3e-31 105.8 0.0 1.5e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGG10109.1 - 5.4e-16 58.0 0.0 2e-15 56.2 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EGG10109.1 - 1e-09 39.1 0.0 2.3e-09 37.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGG10109.1 - 2.5e-07 31.0 0.1 6.6e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase EVE PF01878.13 EGG10110.1 - 2.7e-44 150.6 0.0 5.3e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 EVE domain Response_reg PF00072.19 EGG10111.1 - 1.1e-47 160.6 0.4 2.3e-26 91.9 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 EGG10111.1 - 5.4e-43 145.2 0.2 3.3e-20 71.8 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGG10111.1 - 9.1e-19 67.2 0.6 4.8e-11 42.4 0.1 3.2 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EGG10111.1 - 8.7e-09 35.3 0.0 2.3e-06 27.6 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EGG10111.1 - 1.1e-05 25.7 0.0 3.8e-05 23.9 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EGG10111.1 - 0.00011 21.9 0.3 0.00051 19.8 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 EGG10111.1 - 0.00016 21.7 0.0 0.00066 19.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold GAF_3 PF13492.1 EGG10111.1 - 0.0041 17.2 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c_5 PF14501.1 EGG10111.1 - 0.012 15.2 0.0 0.82 9.4 0.0 2.6 2 0 0 2 2 2 0 GHKL domain IF4E PF01652.13 EGG10113.1 - 1.3e-53 180.9 1.1 1.4e-53 180.8 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E bZIP_2 PF07716.10 EGG10114.1 - 4.8e-05 23.1 15.6 4.8e-05 23.1 10.8 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_C PF12498.3 EGG10114.1 - 0.025 15.7 1.6 0.025 15.7 1.1 4.3 2 1 0 2 2 2 0 Basic leucine-zipper C terminal bZIP_1 PF00170.16 EGG10114.1 - 0.12 12.3 20.4 1.2 9.0 10.0 2.8 3 0 0 3 3 3 0 bZIP transcription factor APG6 PF04111.7 EGG10114.1 - 1.3 7.9 6.7 2.9 6.8 4.6 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EGG10114.1 - 3.1 6.0 4.0 4.4 5.6 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FAD_binding_3 PF01494.14 EGG10115.1 - 5.9e-14 51.8 0.0 7.1e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain PhnA_Zn_Ribbon PF08274.7 EGG10119.1 - 2 8.2 4.8 4.5 7.1 0.3 2.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon FAD_binding_3 PF01494.14 EGG10120.1 - 1.2e-46 159.4 0.0 1.8e-46 158.8 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EGG10120.1 - 9.5e-05 21.3 0.0 0.00014 20.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_3 PF13738.1 EGG10120.1 - 0.00044 20.3 0.0 0.00081 19.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGG10120.1 - 0.00059 19.8 0.0 0.0019 18.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGG10120.1 - 0.00097 18.1 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGG10120.1 - 0.0044 16.8 0.1 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EGG10120.1 - 0.0086 14.9 0.0 0.039 12.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EGG10120.1 - 0.013 15.9 0.0 0.038 14.3 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGG10120.1 - 0.098 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein YjeF_N PF03853.10 EGG10120.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus TrkA_N PF02254.13 EGG10120.1 - 0.12 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 EGG10120.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.20 EGG10121.1 - 1.1e-72 244.3 0.0 1.4e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG10121.1 - 3.8e-37 127.7 0.0 5.1e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG10121.1 - 2.3e-08 33.3 0.0 3.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YukC PF10140.4 EGG10121.1 - 0.0034 15.9 0.2 0.0051 15.4 0.1 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EGG10121.1 - 0.18 11.5 0.8 1.2 8.8 0.6 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family PseudoU_synth_2 PF00849.17 EGG10122.1 - 5.7e-23 81.5 0.0 8.7e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Proteasome PF00227.21 EGG10123.1 - 3e-48 163.6 0.0 3.8e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EGG10123.1 - 1.2e-07 30.8 0.0 3e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal FliJ PF02050.11 EGG10125.1 - 0.023 14.7 0.6 0.074 13.1 0.4 1.9 1 0 0 1 1 1 0 Flagellar FliJ protein TMCO5 PF14992.1 EGG10125.1 - 0.14 11.2 5.3 1.3 8.0 0.5 2.2 1 1 1 2 2 2 0 TMCO5 family Lzipper-MIP1 PF14389.1 EGG10125.1 - 0.15 12.2 2.9 15 5.7 0.0 2.9 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 SlyX PF04102.7 EGG10125.1 - 0.23 11.8 5.8 0.35 11.2 0.6 3.2 2 1 1 3 3 3 0 SlyX FlaC_arch PF05377.6 EGG10125.1 - 0.24 11.3 1.7 14 5.7 0.1 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EGG10125.1 - 0.96 9.0 7.7 2.7 7.5 5.3 1.8 1 1 0 1 1 1 0 IncA protein Tropomyosin_1 PF12718.2 EGG10125.1 - 1.9 8.3 8.2 2 8.2 3.0 2.5 1 1 1 2 2 2 0 Tropomyosin like ATG16 PF08614.6 EGG10125.1 - 5.8 6.6 12.2 0.38 10.5 4.8 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) MgtE PF01769.11 EGG10128.1 - 0.054 13.7 2.7 0.099 12.9 1.9 1.4 1 0 0 1 1 1 0 Divalent cation transporter zf-CCHC PF00098.18 EGG10132.1 - 0.0058 16.5 2.9 0.0094 15.8 2.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGG10132.1 - 0.14 11.9 0.9 0.31 10.8 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle GPI-anchored PF10342.4 EGG10133.1 - 0.015 15.7 0.7 0.019 15.4 0.5 1.3 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Phage_G PF02306.10 EGG10133.1 - 0.015 14.9 0.7 0.041 13.5 0.4 1.7 1 1 1 2 2 2 0 Major spike protein (G protein) Ribosomal_L7Ae PF01248.21 EGG10135.1 - 1.9e-19 68.9 0.1 2.4e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF374 PF04028.8 EGG10135.1 - 0.025 13.7 0.3 1.2 8.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Acyltransferase PF01553.16 EGG10135.1 - 0.056 12.8 0.0 0.14 11.6 0.0 1.5 1 1 1 2 2 2 0 Acyltransferase DNA_photolyase PF00875.13 EGG10135.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 DNA photolyase 14-3-3 PF00244.15 EGG10136.1 - 2.3e-116 386.8 2.7 2.9e-116 386.5 1.9 1.1 1 0 0 1 1 1 1 14-3-3 protein STT3 PF02516.9 EGG10138.1 - 0.16 10.9 6.7 0.22 10.4 4.6 1.1 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit Ras PF00071.17 EGG10139.1 - 1.7e-54 183.5 0.1 2e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG10139.1 - 7.3e-21 74.8 0.0 9.9e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG10139.1 - 2.9e-14 52.6 0.0 3.8e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGG10139.1 - 2.9e-06 27.2 0.0 1e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGG10139.1 - 4.8e-06 26.1 0.0 1.1e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGG10139.1 - 4.4e-05 22.7 0.0 5.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGG10139.1 - 0.00044 19.5 0.0 0.00089 18.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EGG10139.1 - 0.025 13.7 0.1 0.17 11.0 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EGG10139.1 - 0.026 14.0 0.1 0.054 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain Spt5-NGN PF03439.8 EGG10140.1 - 3.5e-25 87.5 0.0 6.1e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 EGG10140.1 - 4.2e-18 64.2 7.4 0.0016 18.0 0.1 6.8 6 0 0 6 6 6 5 KOW motif Spt5_N PF11942.3 EGG10140.1 - 2.9e-07 31.0 9.9 2.9e-07 31.0 6.9 2.7 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 EGG10140.1 - 1.1e-06 29.1 24.4 1.1e-06 29.1 16.9 3.6 1 1 2 3 3 3 1 Spt5 C-terminal nonapeptide repeat binding Spt4 NusG PF02357.14 EGG10140.1 - 0.087 13.0 0.1 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Transcription termination factor nusG Spore_coat_CotO PF14153.1 EGG10140.1 - 0.52 9.7 6.2 1.6 8.1 4.3 1.8 1 0 0 1 1 1 0 Spore coat protein CotO Ribosomal_L31e PF01198.14 EGG10141.1 - 4.5e-37 125.5 1.4 5.8e-37 125.2 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Cyclin_N PF00134.18 EGG10142.1 - 3.7e-35 120.2 0.1 7.8e-35 119.2 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGG10142.1 - 1.7e-06 27.9 0.0 3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain CytochromB561_N PF09786.4 EGG10142.1 - 3.5 5.9 8.1 0.16 10.3 0.4 2.0 2 0 0 2 2 2 0 Cytochrome B561, N terminal LSM PF01423.17 EGG10144.1 - 2.6e-16 58.9 0.4 3.3e-16 58.6 0.3 1.2 1 0 0 1 1 1 1 LSM domain Glyco_hydro_26 PF02156.10 EGG10145.1 - 0.026 14.0 0.7 0.033 13.6 0.4 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 26 Rad60-SLD PF11976.3 EGG10146.1 - 1.2e-14 53.6 0.0 1.5e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGG10146.1 - 3.5e-06 26.3 0.0 5e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin family YjeF_N PF03853.10 EGG10147.1 - 9.1e-38 129.5 0.0 1.1e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.20 EGG10147.1 - 0.035 13.3 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Amino_oxidase PF01593.19 EGG10147.1 - 0.13 11.2 0.2 2.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lipase_3 PF01764.20 EGG10148.1 - 2.3e-17 62.9 0.0 5e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGG10148.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family ThiI PF02568.9 EGG10152.1 - 0.083 12.3 0.0 0.085 12.3 0.0 1.1 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) GldM_N PF12081.3 EGG10153.1 - 0.0063 16.0 1.5 0.0091 15.5 1.1 1.2 1 0 0 1 1 1 1 GldM N-terminal domain GAGA_bind PF06217.7 EGG10153.1 - 0.071 13.0 1.9 0.085 12.8 1.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CAF-1_p150 PF11600.3 EGG10153.1 - 2.3 7.5 19.9 3.3 7.0 13.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SRP54 PF00448.17 EGG10154.1 - 9.3e-76 253.6 0.2 9.3e-76 253.6 0.1 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EGG10154.1 - 1.6e-21 76.5 1.3 1.6e-21 76.5 0.9 3.9 4 1 1 5 5 5 1 Signal peptide binding domain SRP54_N PF02881.14 EGG10154.1 - 1.1e-12 47.8 0.5 2.3e-12 46.8 0.4 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EGG10154.1 - 1.5e-06 27.7 0.1 4.6e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EGG10154.1 - 3.3e-06 27.0 0.2 1.1e-05 25.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 EGG10154.1 - 0.00013 21.6 0.0 0.00031 20.4 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EGG10154.1 - 0.00022 20.7 0.1 0.0014 18.1 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EGG10154.1 - 0.00032 19.5 2.9 0.011 14.5 0.0 3.3 2 1 1 3 3 3 1 ArgK protein AAA_31 PF13614.1 EGG10154.1 - 0.00039 20.3 0.0 0.31 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGG10154.1 - 0.0022 18.1 0.0 0.01 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EGG10154.1 - 0.0027 17.3 0.0 0.008 15.8 0.0 1.8 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_10 PF12846.2 EGG10154.1 - 0.0051 16.2 0.0 0.06 12.7 0.0 2.3 2 1 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EGG10154.1 - 0.0097 15.9 3.7 0.011 15.7 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EGG10154.1 - 0.013 16.3 0.0 0.026 15.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EGG10154.1 - 0.014 14.6 0.3 2.5 7.2 0.0 3.0 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EGG10154.1 - 0.028 13.9 0.1 0.18 11.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 EGG10154.1 - 0.039 13.0 0.9 0.059 12.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin EcsC PF12787.2 EGG10154.1 - 0.05 13.0 6.7 0.45 9.8 0.0 3.0 2 1 1 3 3 3 0 EcsC protein family 6PF2K PF01591.13 EGG10154.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ArsA_ATPase PF02374.10 EGG10154.1 - 0.076 12.0 0.0 2.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_28 PF13521.1 EGG10154.1 - 0.19 11.6 1.2 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF4168 PF13767.1 EGG10154.1 - 0.71 10.5 3.8 0.72 10.5 0.9 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4168) Sec66 PF09802.4 EGG10155.1 - 3.1e-40 137.6 0.0 5e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 T4SS PF07996.6 EGG10155.1 - 7e-05 22.7 4.8 0.012 15.4 1.5 2.3 1 1 1 2 2 2 2 Type IV secretion system proteins DUF3123 PF11321.3 EGG10155.1 - 0.076 13.2 0.1 0.17 12.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3123) IlvC PF01450.14 EGG10155.1 - 0.17 11.7 1.0 0.68 9.8 0.1 2.3 1 1 2 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF4653 PF15546.1 EGG10155.1 - 0.25 10.5 4.9 2.6 7.2 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4653) SQS_PSY PF00494.14 EGG10156.1 - 1.9e-48 165.1 0.0 2.8e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase eIF3_p135 PF12807.2 EGG10156.1 - 0.073 13.0 0.2 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 C1_2 PF03107.11 EGG10157.1 - 7.3 6.8 8.1 38 4.5 0.1 3.2 2 1 0 2 2 2 0 C1 domain Rad60-SLD_2 PF13881.1 EGG10158.1 - 0.0002 21.2 0.0 0.00048 19.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF605 PF04652.11 EGG10158.1 - 0.00041 19.8 5.5 0.00041 19.8 3.8 3.1 3 0 0 3 3 3 1 Vta1 like DUF2407 PF10302.4 EGG10158.1 - 0.0017 18.5 0.1 0.0057 16.8 0.0 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Peptidase_M36 PF02128.10 EGG10159.1 - 1.3e-133 445.5 8.1 1.2e-125 419.3 3.1 2.2 1 1 1 2 2 2 2 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.10 EGG10159.1 - 0.018 14.7 0.0 0.062 13.0 0.0 1.9 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Rad21_Rec8_N PF04825.8 EGG10161.1 - 2.4e-32 111.1 0.0 4.4e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EGG10161.1 - 4.5e-12 44.9 0.0 9e-12 43.9 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EGG10161.1 - 0.12 11.9 0.1 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 ScpA/B protein PLDc PF00614.17 EGG10162.1 - 1.2e-15 56.7 3.9 4.7e-10 38.9 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EGG10162.1 - 4.7e-14 52.2 0.0 6.3e-07 29.1 0.0 3.8 3 1 1 4 4 4 3 PLD-like domain Amidohydro_2 PF04909.9 EGG10163.1 - 1.9e-09 37.4 0.0 3.7e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EGG10163.1 - 1.8e-08 34.7 0.2 5.2e-08 33.2 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGG10163.1 - 0.0031 17.2 0.1 0.0064 16.1 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family DUF3018 PF11455.3 EGG10164.1 - 0.043 13.7 0.0 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) Atx10homo_assoc PF09759.4 EGG10166.1 - 2.8e-14 52.6 1.4 4.9e-14 51.9 0.1 2.0 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Cse1 PF08506.5 EGG10166.1 - 0.0044 15.6 4.3 0.0047 15.5 3.0 1.1 1 0 0 1 1 1 1 Cse1 DUF4250 PF14056.1 EGG10166.1 - 0.07 12.8 0.4 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Arf PF00025.16 EGG10167.1 - 4.2e-21 74.9 0.1 5.6e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGG10167.1 - 3e-08 32.7 1.3 2.1e-05 23.4 0.1 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EGG10167.1 - 1.7e-05 25.3 0.0 2e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGG10167.1 - 2.9e-05 23.3 0.0 4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGG10167.1 - 7.9e-05 22.5 0.0 9.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGG10167.1 - 0.0015 17.7 0.0 0.0017 17.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Thymidylate_kin PF02223.12 EGG10167.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase AAA_14 PF13173.1 EGG10167.1 - 0.017 15.0 0.1 0.028 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGG10167.1 - 0.037 14.1 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGG10167.1 - 0.08 12.6 0.1 0.15 11.7 0.1 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EGG10167.1 - 0.088 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EGG10167.1 - 0.12 12.6 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EGG10167.1 - 0.15 12.0 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Thioredoxin_8 PF13905.1 EGG10168.1 - 6e-10 39.1 1.4 3.5e-09 36.6 0.4 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGG10168.1 - 0.0017 18.5 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Tryp_alpha_amyl PF00234.17 EGG10170.1 - 0.069 13.3 1.2 0.31 11.2 1.1 1.9 1 1 0 1 1 1 0 Protease inhibitor/seed storage/LTP family Nucleoporin2 PF04096.9 EGG10172.1 - 0.016 15.0 0.0 0.39 10.5 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin autopeptidase WD40 PF00400.27 EGG10173.1 - 1e-48 161.5 20.9 2.3e-11 43.1 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EGG10173.1 - 1.2e-07 31.6 2.7 0.00059 19.6 0.0 3.8 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGG10173.1 - 3.2e-05 22.2 4.9 0.14 10.2 0.3 4.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Utp8 PF10395.4 EGG10173.1 - 0.006 14.9 0.7 0.089 11.0 0.3 2.0 2 0 0 2 2 2 1 Utp8 family Cytochrom_D1 PF02239.11 EGG10173.1 - 0.055 11.7 0.1 1.3 7.2 0.0 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain SseB_C PF14581.1 EGG10175.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 SseB protein C-terminal domain GST_N_3 PF13417.1 EGG10179.1 - 8.3e-10 38.7 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGG10179.1 - 2.4e-07 30.6 0.0 4.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGG10179.1 - 0.00022 21.0 0.0 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGG10179.1 - 0.00026 21.0 0.0 0.00079 19.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGG10179.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Gti1_Pac2 PF09729.4 EGG10180.1 - 8.5e-55 185.1 0.9 8.5e-55 185.1 0.6 2.5 2 1 0 2 2 2 1 Gti1/Pac2 family Pept_tRNA_hydro PF01195.14 EGG10181.1 - 5.4e-15 55.3 0.0 6.4e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase BSP_II PF05432.6 EGG10182.1 - 0.03 13.5 1.8 0.05 12.8 1.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Cadherin-like PF12733.2 EGG10182.1 - 0.061 13.5 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain Corona_nucleoca PF00937.13 EGG10184.1 - 0.039 12.9 2.7 0.044 12.7 1.9 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Nup84_Nup100 PF04121.8 EGG10185.1 - 5.2e-107 358.2 3.9 6.1e-60 202.7 0.9 3.1 3 0 0 3 3 3 3 Nuclear pore protein 84 / 107 PMI_typeI PF01238.16 EGG10186.1 - 6.6e-118 393.9 0.0 8.8e-118 393.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 EGG10186.1 - 0.021 14.5 0.1 12 5.5 0.0 3.1 4 0 0 4 4 4 0 AraC-like ligand binding domain Antimicrobial_2 PF08023.7 EGG10186.1 - 0.086 13.1 0.0 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 Frog antimicrobial peptide Brix PF04427.13 EGG10187.1 - 7.6e-33 113.7 0.0 9.5e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain UbiA PF01040.13 EGG10188.1 - 4.7e-18 65.3 1.4 5e-18 65.2 1.0 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family L27_1 PF09058.5 EGG10193.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 L27_1 DUF2151 PF10221.4 EGG10196.1 - 0.034 12.3 0.6 0.04 12.1 0.4 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator PH_5 PF15405.1 EGG10196.1 - 0.061 13.2 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Anophelin PF10731.4 EGG10196.1 - 0.16 12.0 1.5 0.31 11.1 1.0 1.4 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito DUF4611 PF15387.1 EGG10196.1 - 0.26 11.4 5.7 0.068 13.3 1.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PADR1 PF08063.7 EGG10199.1 - 0.025 13.9 2.0 0.052 12.9 1.4 1.4 1 0 0 1 1 1 0 PADR1 (NUC008) domain PPP4R2 PF09184.6 EGG10200.1 - 0.013 15.0 14.8 0.015 14.8 10.3 1.1 1 0 0 1 1 1 0 PPP4R2 APC2 PF08672.6 EGG10200.1 - 0.05 13.8 0.0 0.076 13.2 0.0 1.3 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 Ycf1 PF05758.7 EGG10200.1 - 1.7 6.2 8.4 1.6 6.3 5.8 1.1 1 0 0 1 1 1 0 Ycf1 Paf1 PF03985.8 EGG10200.1 - 4.5 5.9 16.8 5.1 5.7 11.6 1.2 1 0 0 1 1 1 0 Paf1 Kelch_5 PF13854.1 EGG10202.1 - 1.7e-06 27.8 0.0 2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Kelch motif Kelch_1 PF01344.20 EGG10202.1 - 6.2e-06 25.6 0.0 7e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.1 EGG10202.1 - 2.6e-05 23.8 0.0 3.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EGG10202.1 - 3.6e-05 23.7 0.0 4.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.10 EGG10202.1 - 0.00021 20.9 0.1 0.00028 20.5 0.1 1.3 1 1 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 EGG10202.1 - 0.0018 18.3 0.5 0.0027 17.8 0.1 1.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.1 EGG10203.1 - 9.2e-10 38.4 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_4 PF13418.1 EGG10203.1 - 8.4e-08 31.8 1.0 5.6e-07 29.2 0.0 2.0 1 1 1 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 EGG10203.1 - 0.00024 20.5 0.1 0.002 17.6 0.0 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 EGG10203.1 - 0.00032 20.7 0.1 0.00063 19.8 0.0 1.6 1 1 1 2 2 2 1 Kelch motif Kelch_2 PF07646.10 EGG10203.1 - 0.0018 17.9 0.3 0.0071 16.0 0.1 1.9 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 EGG10203.1 - 0.0052 16.7 0.5 0.053 13.4 0.0 2.1 2 0 0 2 2 2 1 Kelch motif RNA_pol_Rpb2_6 PF00562.23 EGG10204.1 - 1.9e-07 30.1 0.0 0.00037 19.3 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 HTH_21 PF13276.1 EGG10205.1 - 2.2e-05 24.3 3.4 0.00041 20.3 0.9 3.2 3 1 0 3 3 3 1 HTH-like domain HTH_32 PF13565.1 EGG10205.1 - 0.00016 22.4 1.2 0.15 12.8 0.0 3.4 3 0 0 3 3 3 1 Homeodomain-like domain RecX PF02631.11 EGG10205.1 - 0.013 15.7 0.2 0.026 14.7 0.0 1.6 2 0 0 2 2 2 0 RecX family HTH_33 PF13592.1 EGG10205.1 - 0.019 14.4 0.6 33 4.1 0.0 4.2 4 0 0 4 4 4 0 Winged helix-turn helix Mpv17_PMP22 PF04117.7 EGG10206.1 - 1.7e-07 30.7 1.0 2.9e-07 29.9 0.7 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF4083 PF13314.1 EGG10207.1 - 0.0078 16.0 0.5 0.014 15.1 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) PsbT PF01405.12 EGG10207.1 - 2.3 7.8 5.2 4.6 6.9 3.6 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Pkinase PF00069.20 EGG10208.1 - 4.6e-59 199.6 0.0 6.9e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG10208.1 - 1.7e-32 112.4 0.0 6.4e-32 110.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG10208.1 - 0.0005 19.1 0.0 0.00074 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGG10208.1 - 0.062 13.0 0.2 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 EGG10209.1 - 5.9e-14 51.3 21.7 0.021 14.6 0.1 9.9 11 0 0 11 11 11 5 WD domain, G-beta repeat Pyr_redox_2 PF07992.9 EGG10210.1 - 6.1e-31 107.8 0.0 7.4e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGG10210.1 - 4.3e-17 62.2 0.1 1.9e-14 53.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGG10210.1 - 2.2e-07 31.1 0.1 0.0011 19.1 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGG10210.1 - 3e-06 26.5 0.0 2.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EGG10210.1 - 2e-05 23.6 0.8 0.0027 16.6 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 EGG10210.1 - 0.00015 20.7 3.4 0.011 14.6 0.1 3.8 4 1 1 5 5 5 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EGG10210.1 - 0.00085 19.3 0.1 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGG10210.1 - 0.0015 17.5 1.3 0.09 11.6 0.1 3.0 1 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EGG10210.1 - 0.0041 17.3 0.0 0.34 11.1 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EGG10210.1 - 0.0041 17.2 0.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EGG10210.1 - 0.0053 15.9 0.3 0.16 11.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGG10210.1 - 0.012 14.0 0.3 0.038 12.4 0.2 1.8 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.14 EGG10210.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EGG10210.1 - 0.019 13.6 0.1 0.077 11.6 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.11 EGG10210.1 - 0.074 12.4 0.7 13 5.2 0.0 2.7 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA K_oxygenase PF13434.1 EGG10210.1 - 0.082 11.8 0.0 6.4 5.5 0.0 3.0 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.16 EGG10210.1 - 0.097 12.4 0.0 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 ThiF family NAD_binding_9 PF13454.1 EGG10210.1 - 0.13 12.0 0.0 10 5.8 0.0 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ribosomal_L5_C PF00673.16 EGG10212.1 - 4.3e-11 42.4 0.0 1.2e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 ribosomal L5P family C-terminus PsbW PF07123.7 EGG10213.1 - 1.8 8.6 4.9 2.1 8.4 3.0 1.4 1 1 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) PTR2 PF00854.16 EGG10214.1 - 2.4e-46 158.2 11.7 6e-45 153.6 8.1 2.6 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EGG10214.1 - 3.9e-07 29.1 23.6 1.5e-06 27.2 15.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily RTBV_P46 PF06216.6 EGG10215.1 - 0.0021 17.0 4.5 0.0033 16.3 3.1 1.2 1 0 0 1 1 1 1 Rice tungro bacilliform virus P46 protein Rootletin PF15035.1 EGG10215.1 - 0.032 14.2 18.4 0.087 12.8 12.7 1.7 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FlaC_arch PF05377.6 EGG10215.1 - 0.16 11.8 5.1 0.81 9.6 3.6 2.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Mnd1 PF03962.10 EGG10215.1 - 3.5 7.2 21.4 1.1 8.8 4.9 2.5 1 1 1 2 2 2 0 Mnd1 family Arm PF00514.18 EGG10216.1 - 2.9e-91 296.5 11.8 1.9e-12 46.4 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGG10216.1 - 4.1e-25 87.8 0.2 7.4e-10 38.9 0.0 5.7 1 1 3 5 5 5 5 HEAT repeats IBB PF01749.15 EGG10216.1 - 6.7e-24 83.8 1.5 1.1e-23 83.1 1.1 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EGG10216.1 - 8.5e-23 80.2 2.4 1.4e-07 31.7 0.0 6.0 4 1 2 6 6 6 3 HEAT-like repeat HEAT PF02985.17 EGG10216.1 - 1.7e-17 61.8 1.3 1.8e-06 27.5 0.0 6.7 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.8 EGG10216.1 - 2.8e-10 39.7 0.0 0.0039 16.3 0.0 4.2 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EGG10216.1 - 7e-08 31.2 0.0 6.5e-06 24.7 0.0 2.8 1 1 2 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.1 EGG10216.1 - 5.9e-06 26.1 2.2 0.42 10.5 0.0 4.5 3 2 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 EGG10216.1 - 0.00012 21.9 0.0 0.39 10.6 0.0 4.2 4 1 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.11 EGG10216.1 - 0.0015 18.8 2.8 0.55 10.8 0.1 5.1 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 EGG10216.1 - 0.0087 14.3 0.2 0.42 8.8 0.0 2.7 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit V-ATPase_H_N PF03224.9 EGG10216.1 - 0.03 13.4 0.0 3 6.8 0.0 2.9 1 1 1 2 2 2 0 V-ATPase subunit H Mo25 PF08569.6 EGG10216.1 - 0.07 12.1 0.0 0.27 10.2 0.0 2.0 3 0 0 3 3 3 0 Mo25-like HMG_box PF00505.14 EGG10218.1 - 0.047 13.9 0.2 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box Sec7 PF01369.15 EGG10223.1 - 1.3e-41 142.3 0.1 2.6e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EGG10223.1 - 0.017 15.2 0.2 0.017 15.2 0.1 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain PH_10 PF15411.1 EGG10223.1 - 0.08 13.1 0.3 0.22 11.6 0.2 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Oxidored_q1 PF00361.15 EGG10224.1 - 1.5e-20 73.5 11.6 1.6e-20 73.4 8.0 1.0 1 0 0 1 1 1 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Chromate_transp PF02417.10 EGG10224.1 - 0.071 12.7 5.7 0.084 12.4 3.9 1.1 1 0 0 1 1 1 0 Chromate transporter Dynactin_p62 PF05502.8 EGG10225.1 - 3.4e-93 313.0 0.5 5.5e-93 312.3 0.4 1.3 1 0 0 1 1 1 1 Dynactin p62 family Polysacc_deac_1 PF01522.16 EGG10226.1 - 7.4e-28 96.6 0.0 1.1e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase SPDY PF03771.11 EGG10226.1 - 0.0085 15.5 1.8 0.13 11.7 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF317) Glyco_hydro_57 PF03065.10 EGG10226.1 - 0.01 14.7 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 MADF_DNA_bdg PF10545.4 EGG10227.1 - 0.18 11.9 1.2 12 6.1 0.3 2.7 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like NUC153 PF08159.7 EGG10228.1 - 3e-11 42.6 11.0 4.5e-11 42.1 0.4 3.2 3 0 0 3 3 3 2 NUC153 domain PBD PF00786.23 EGG10228.1 - 0.27 11.6 2.1 26 5.3 0.4 3.5 2 0 0 2 2 2 0 P21-Rho-binding domain Alpha_kinase PF02816.13 EGG10229.1 - 3.2e-12 46.5 0.0 3.7e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Git3 PF11710.3 EGG10231.1 - 1.2e-15 57.5 9.7 2.1e-15 56.8 6.7 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 EGG10231.1 - 1.6e-06 27.2 7.4 2.3e-06 26.7 5.0 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 EGG10231.1 - 3.2e-06 26.4 4.5 3.2e-06 26.4 3.1 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 EGG10231.1 - 0.00061 19.4 0.1 0.00061 19.4 0.0 2.7 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Ocular_alb PF02101.10 EGG10231.1 - 0.099 11.2 5.4 0.14 10.7 3.7 1.2 1 0 0 1 1 1 0 Ocular albinism type 1 protein WD40 PF00400.27 EGG10232.1 - 4.4e-29 99.2 7.7 9.5e-06 25.3 0.1 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat Prp19 PF08606.6 EGG10232.1 - 1.8e-28 98.0 0.5 4.3e-28 96.8 0.3 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like eIF2A PF08662.6 EGG10232.1 - 0.00031 20.4 0.0 0.023 14.4 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A U-box PF04564.10 EGG10232.1 - 0.00061 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain BBS2_Mid PF14783.1 EGG10232.1 - 0.011 15.5 0.3 0.058 13.1 0.0 2.3 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region zf-Nse PF11789.3 EGG10232.1 - 0.024 14.1 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3166 PF11365.3 EGG10232.1 - 0.13 12.7 0.1 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) Cep57_CLD_2 PF14197.1 EGG10232.1 - 3 7.8 5.6 2.2 8.2 1.8 2.3 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Yip1 PF04893.12 EGG10233.1 - 5.1e-11 42.3 12.9 1.7e-10 40.7 8.2 2.0 2 0 0 2 2 2 1 Yip1 domain VRR_NUC PF08774.6 EGG10234.1 - 0.0094 15.9 0.0 4.1 7.4 0.0 2.6 1 1 1 2 2 2 2 VRR-NUC domain DUF2007 PF09413.5 EGG10234.1 - 0.069 12.9 0.4 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) UBN2 PF14223.1 EGG10238.1 - 4.5e-05 23.2 0.3 8.1e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG10238.1 - 0.00034 20.1 0.3 0.0007 19.1 0.2 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EGG10238.1 - 0.0097 15.4 2.0 0.076 12.5 0.1 2.8 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type HTH_19 PF12844.2 EGG10238.1 - 0.037 14.0 0.4 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Paramyxo_C PF01692.13 EGG10241.1 - 0.43 10.1 10.7 0.5 9.9 7.1 1.3 1 1 0 1 1 1 0 Paramyxovirus non-structural protein c SOBP PF15279.1 EGG10241.1 - 1.3 9.3 12.9 1.5 9.1 9.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Pex14_N PF04695.8 EGG10241.1 - 2.8 8.0 9.6 4.4 7.3 6.4 1.6 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region G-alpha PF00503.15 EGG10242.1 - 9e-27 93.7 0.5 1.4e-21 76.6 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.16 EGG10242.1 - 0.00031 20.0 0.0 0.00038 19.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family LMBR1 PF04791.11 EGG10244.1 - 0.11 11.0 5.7 0.15 10.5 4.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein GAGA_bind PF06217.7 EGG10244.1 - 0.19 11.6 15.9 0.32 10.9 11.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family EFP_N PF08207.7 EGG10246.1 - 0.057 13.2 0.3 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Mis14 PF08641.7 EGG10248.1 - 0.024 14.6 0.7 0.036 14.1 0.5 1.3 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Metaviral_G PF09595.5 EGG10248.1 - 0.046 13.3 1.6 0.06 12.9 1.1 1.1 1 0 0 1 1 1 0 Metaviral_G glycoprotein FadA PF09403.5 EGG10248.1 - 0.25 11.3 1.4 0.57 10.2 0.9 1.5 1 1 1 2 2 2 0 Adhesion protein FadA Nop25 PF09805.4 EGG10248.1 - 0.95 9.5 5.4 1.1 9.3 3.8 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Tmemb_cc2 PF10267.4 EGG10248.1 - 1.1 7.8 5.2 1.2 7.6 3.6 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Baculo_PEP_C PF04513.7 EGG10251.1 - 0.00081 19.2 0.1 0.0014 18.5 0.1 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Toxin_52 PF15605.1 EGG10251.1 - 0.016 15.1 0.0 0.039 13.8 0.0 1.6 1 1 1 2 2 2 0 Putative toxin 52 Bacillus_HBL PF05791.6 EGG10251.1 - 0.021 14.1 0.4 0.032 13.6 0.3 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.7 EGG10251.1 - 0.075 12.8 0.5 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.6 EGG10251.1 - 0.094 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF2450 PF10475.4 EGG10251.1 - 0.14 11.0 0.6 0.19 10.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) FAM178 PF14816.1 EGG10252.1 - 0.037 12.7 3.0 0.043 12.5 2.0 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 Rhabdo_ncap PF00945.13 EGG10252.1 - 0.087 11.3 2.1 0.09 11.3 1.5 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Pox_Ag35 PF03286.9 EGG10252.1 - 0.1 12.0 7.8 0.12 11.8 5.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GCD14 PF08704.5 EGG10252.1 - 0.23 10.9 4.0 0.27 10.7 2.8 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF2457 PF10446.4 EGG10252.1 - 0.97 8.0 8.6 1 8.0 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Vfa1 PF08432.5 EGG10252.1 - 2.8 7.9 8.5 3.2 7.7 5.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 APC_CDC26 PF10471.4 EGG10252.1 - 5.3 7.8 7.6 2 9.2 2.7 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF2428 PF10350.4 EGG10255.1 - 2.5e-44 151.2 0.2 5.3e-44 150.1 0.1 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EGG10255.1 - 1.3e-10 40.4 8.2 0.0027 17.6 0.0 7.1 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EGG10255.1 - 8.7e-07 29.1 6.2 5.8e-05 23.2 0.0 4.8 5 1 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 EGG10255.1 - 1.4e-05 25.4 5.7 0.00027 21.3 0.0 5.0 5 0 0 5 5 5 1 HEAT-like repeat NinB PF05772.7 EGG10255.1 - 0.034 13.7 0.1 0.094 12.3 0.0 1.8 2 0 0 2 2 2 0 NinB protein SNF2_N PF00176.18 EGG10256.1 - 7.7e-62 208.7 0.2 1.8e-61 207.5 0.2 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGG10256.1 - 9.6e-14 51.0 0.0 2.3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGG10256.1 - 8.5e-06 24.7 5.4 9.2e-06 24.6 0.3 2.7 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EGG10256.1 - 3.7e-05 23.2 0.0 0.0001 21.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.24 EGG10256.1 - 0.00012 21.6 17.5 0.00034 20.2 3.8 2.6 2 0 0 2 2 2 2 PHD-finger Ribul_P_3_epim PF00834.14 EGG10256.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family COG2 PF06148.6 EGG10256.1 - 0.28 11.0 4.2 3.2 7.6 0.3 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V-ATPase_C PF03223.10 EGG10257.1 - 3.7e-95 318.9 12.0 4e-95 318.8 8.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Peptidase_M50 PF02163.17 EGG10258.1 - 9.7e-11 40.9 0.8 5.7e-09 35.2 0.0 3.0 2 1 0 2 2 2 1 Peptidase family M50 Chs3p PF12271.3 EGG10258.1 - 0.037 13.0 0.4 0.076 11.9 0.2 1.4 1 0 0 1 1 1 0 Chitin synthase III catalytic subunit FAR1 PF03101.10 EGG10260.1 - 0.15 12.6 0.6 0.36 11.3 0.1 1.8 2 0 0 2 2 2 0 FAR1 DNA-binding domain SWIM PF04434.12 EGG10261.1 - 0.1 12.0 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 SWIM zinc finger EMP24_GP25L PF01105.19 EGG10262.1 - 5.2e-36 124.0 0.0 5.8e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SH3BGR PF04908.10 EGG10264.1 - 2.9e-08 33.5 0.3 7.6e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Metallophos PF00149.23 EGG10265.1 - 4.3e-40 137.2 0.1 6.2e-40 136.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DnaJ PF00226.26 EGG10266.1 - 6.9e-12 44.9 0.3 1.5e-11 43.8 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.11 EGG10267.1 - 2.6e-23 82.3 27.3 7.8e-22 77.4 6.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG10267.1 - 0.00063 18.4 12.2 0.00063 18.4 8.5 2.1 1 1 0 2 2 2 1 Sugar (and other) transporter UNC-93 PF05978.11 EGG10267.1 - 0.0046 16.4 1.8 0.015 14.8 1.2 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 PP2C_2 PF13672.1 EGG10268.1 - 3.4e-12 46.2 0.0 5.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EGG10268.1 - 8.8e-12 45.1 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EGG10268.1 - 7.8e-08 32.0 0.2 3.3e-05 23.3 0.0 2.5 2 1 0 2 2 2 2 Protein phosphatase 2C Tcf25 PF04910.9 EGG10271.1 - 7.1e-80 268.6 0.1 1.3e-79 267.7 0.0 1.5 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.1 EGG10271.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3509 PF12021.3 EGG10271.1 - 1.8 8.3 6.2 0.56 9.9 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) Spore_coat_CotO PF14153.1 EGG10271.1 - 7.1 6.0 17.6 0.79 9.1 1.5 2.8 2 0 0 2 2 2 0 Spore coat protein CotO FancD2 PF14631.1 EGG10272.1 - 0.14 9.2 0.0 0.16 9.0 0.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease FancD2 PF14631.1 EGG10274.1 - 0.17 8.9 0.0 0.21 8.6 0.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Vfa1 PF08432.5 EGG10275.1 - 0.15 12.1 3.6 0.19 11.7 2.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NST1 PF13945.1 EGG10275.1 - 0.39 10.7 6.6 0.6 10.1 4.6 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator IFT43 PF15305.1 EGG10275.1 - 0.44 10.5 6.3 0.44 10.5 3.8 1.3 1 1 0 1 1 1 0 Intraflagellar transport protein 43 ATP-synt_G PF04718.10 EGG10276.1 - 3.4e-17 62.9 0.1 4.5e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Rab5-bind PF09311.6 EGG10277.1 - 0.63 9.9 7.0 0.14 12.0 2.2 1.8 2 0 0 2 2 2 0 Rabaptin-like protein DUF3086 PF11285.3 EGG10278.1 - 0.021 13.6 0.2 0.034 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) EFP PF01132.15 EGG10279.1 - 0.053 13.1 0.1 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain zf-C2H2_jaz PF12171.3 EGG10280.1 - 4.4e-05 23.4 3.3 7e-05 22.8 2.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EGG10280.1 - 0.025 14.8 2.9 0.05 13.9 2.0 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EGG10280.1 - 0.047 13.7 0.1 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Mucin PF01456.12 EGG10280.1 - 0.06 13.1 8.3 0.69 9.6 4.8 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.3 EGG10280.1 - 0.14 11.8 3.3 0.13 11.9 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) zf-C2H2_4 PF13894.1 EGG10280.1 - 0.17 12.2 3.1 0.35 11.2 2.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DUF106 PF01956.11 EGG10281.1 - 4.6e-55 185.7 0.3 7.2e-55 185.0 0.0 1.4 2 0 0 2 2 2 1 Integral membrane protein DUF106 SDP_N PF12278.3 EGG10282.1 - 0.094 12.3 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Sex determination protein N terminal Anoctamin PF04547.7 EGG10284.1 - 7.9e-99 331.3 19.6 1e-98 330.9 13.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Pex16 PF08610.5 EGG10285.1 - 8e-75 251.9 0.8 9.1e-75 251.7 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Molybdopterin PF00384.17 EGG10286.1 - 1.6e-61 208.3 0.0 8.2e-61 206.0 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EGG10286.1 - 1.8e-19 68.6 0.1 4.9e-19 67.2 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 EGG10286.1 - 3.3e-17 62.0 0.1 7.9e-17 60.8 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 EGG10286.1 - 2.8e-14 52.9 0.0 8.1e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EGG10286.1 - 1.2e-08 34.5 0.6 1.2e-08 34.5 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain ECR1_N PF14382.1 EGG10286.1 - 0.1 11.8 0.1 0.58 9.4 0.1 2.2 1 1 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Fer4 PF00037.22 EGG10286.1 - 0.36 10.4 3.1 6.6 6.5 0.3 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain F-box-like PF12937.2 EGG10287.1 - 8.2e-05 22.2 1.8 0.00011 21.8 0.3 2.0 2 0 0 2 2 2 1 F-box-like YhfH PF14149.1 EGG10287.1 - 0.025 14.3 0.1 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 YhfH-like protein F-box PF00646.28 EGG10287.1 - 0.078 12.6 1.1 0.28 10.8 0.8 2.0 1 1 0 1 1 1 0 F-box domain adh_short PF00106.20 EGG10288.1 - 5.6e-06 26.3 0.0 7.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Kinesin PF00225.18 EGG10289.1 - 1.5e-88 296.7 0.6 1.5e-88 296.7 0.4 1.9 2 1 0 2 2 2 1 Kinesin motor domain Lipase_3 PF01764.20 EGG10290.1 - 3.1e-17 62.4 0.0 6.1e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGG10290.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family API5 PF05918.6 EGG10291.1 - 0.062 11.7 5.9 0.11 10.9 4.1 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GRP PF07172.6 EGG10291.1 - 9.5 6.7 16.0 6 7.4 8.5 2.2 2 0 0 2 2 2 0 Glycine rich protein family GHMP_kinases_N PF00288.21 EGG10293.1 - 1.7e-10 40.8 0.0 4e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGG10293.1 - 0.0033 17.5 0.0 0.008 16.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal EXS PF03124.9 EGG10296.1 - 3.3e-60 203.9 4.5 5.4e-60 203.2 3.1 1.3 1 0 0 1 1 1 1 EXS family DUF4401 PF14351.1 EGG10296.1 - 3.8 6.3 14.0 0.077 11.9 0.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4401) Mac PF12464.3 EGG10297.1 - 2.6e-13 49.7 0.0 9.4e-13 47.9 0.0 2.0 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep PF00132.19 EGG10297.1 - 1.3e-11 43.4 11.6 4.9e-10 38.4 4.1 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGG10297.1 - 0.00018 20.9 9.7 0.00026 20.4 2.9 2.5 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase RRM_6 PF14259.1 EGG10297.1 - 0.00039 20.3 0.0 0.027 14.4 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGG10297.1 - 0.0012 18.4 0.0 0.033 13.8 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PPP1R35_C PF15503.1 EGG10297.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus tRNA_anti-codon PF01336.20 EGG10299.1 - 0.022 14.5 0.0 4 7.3 0.0 2.4 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain V-set PF07686.12 EGG10300.1 - 0.13 12.1 0.2 0.82 9.5 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin V-set domain Proteasome PF00227.21 EGG10302.1 - 1.8e-28 99.1 0.0 2.1e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TPR_16 PF13432.1 EGG10303.1 - 4.7e-09 36.6 0.2 1.7e-05 25.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGG10303.1 - 1.3e-08 34.7 0.5 0.0092 16.5 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGG10303.1 - 1.1e-07 31.4 6.5 0.11 12.1 0.3 4.6 5 0 0 5 5 5 3 TPR repeat TPR_19 PF14559.1 EGG10303.1 - 7.1e-07 29.4 3.8 0.68 10.3 0.2 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG10303.1 - 2e-06 27.6 4.2 1.1 9.2 0.2 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGG10303.1 - 0.00043 19.9 5.0 0.93 9.5 0.0 5.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGG10303.1 - 0.0012 18.8 0.0 5.1 7.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGG10303.1 - 0.031 14.0 0.1 5 7.1 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat HemY_N PF07219.8 EGG10303.1 - 0.082 12.4 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 HemY protein N-terminus Med9 PF07544.8 EGG10303.1 - 0.088 12.5 0.5 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TPR_6 PF13174.1 EGG10303.1 - 0.15 12.5 2.7 11 6.7 0.0 4.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGG10303.1 - 0.48 10.3 4.0 3.9 7.4 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Acyl_transf_1 PF00698.16 EGG10304.1 - 9.5e-17 61.3 0.0 2.3e-12 46.8 0.1 2.7 1 1 0 2 2 2 2 Acyl transferase domain TRP PF06011.7 EGG10305.1 - 0.15 10.6 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Pkinase PF00069.20 EGG10306.1 - 1.3e-21 76.9 3.3 1.1e-20 73.9 1.7 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG10306.1 - 3e-12 46.1 0.4 4.6e-12 45.5 0.3 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EGG10306.1 - 0.0014 17.9 0.2 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 EGG10306.1 - 0.0025 17.2 0.3 0.0063 15.8 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Amidase_6 PF12671.2 EGG10306.1 - 0.0073 16.3 1.6 0.017 15.1 1.1 1.6 1 0 0 1 1 1 1 Putative amidase domain Seadorna_VP7 PF07387.6 EGG10306.1 - 0.013 14.3 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 EGG10306.1 - 0.018 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HMG_box PF00505.14 EGG10307.1 - 0.0096 16.1 0.0 0.041 14.1 0.0 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGG10307.1 - 0.029 14.7 2.3 0.046 14.1 0.1 2.3 2 0 0 2 2 2 0 HMG-box domain Senescence PF06911.7 EGG10307.1 - 0.073 12.7 5.2 0.13 11.9 0.0 2.7 3 0 0 3 3 3 0 Senescence-associated protein zf-CCHC_3 PF13917.1 EGG10308.1 - 0.00033 20.3 0.9 0.00059 19.5 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGG10308.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EGG10308.1 - 0.19 11.7 2.5 0.28 11.1 1.7 1.3 1 0 0 1 1 1 0 Zinc knuckle CFEM PF05730.6 EGG10309.1 - 2.3e-08 33.7 8.0 2.3e-08 33.7 5.6 2.1 2 0 0 2 2 2 1 CFEM domain Strabismus PF06638.6 EGG10310.1 - 0.32 9.2 4.3 0.55 8.4 3.0 1.3 1 0 0 1 1 1 0 Strabismus protein Pox_Ag35 PF03286.9 EGG10310.1 - 1.3 8.5 15.3 0.049 13.1 3.8 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein MFS_1 PF07690.11 EGG10311.1 - 1.7e-34 119.0 37.4 8.6e-27 93.7 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG10311.1 - 1.3e-23 83.3 17.6 7.7e-23 80.7 12.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF485 PF04341.7 EGG10311.1 - 0.13 11.9 3.9 0.19 11.4 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function, DUF485 NfeD PF01957.13 EGG10311.1 - 0.7 10.0 8.6 0.32 11.1 0.1 3.1 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding ATP_bind_1 PF03029.12 EGG10312.1 - 7.1e-83 277.7 0.2 1.3e-82 276.9 0.0 1.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EGG10312.1 - 6.4e-09 35.5 0.0 5.8e-08 32.3 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGG10312.1 - 5.5e-05 23.3 0.0 0.00012 22.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EGG10312.1 - 6.1e-05 22.5 0.1 0.0013 18.2 0.0 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 EGG10312.1 - 7e-05 22.3 0.2 0.0002 20.8 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 EGG10312.1 - 0.00017 21.0 0.0 0.012 15.0 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EGG10312.1 - 0.00035 21.3 0.0 0.0017 19.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGG10312.1 - 0.00041 20.2 0.1 0.0011 18.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EGG10312.1 - 0.00051 19.9 0.0 0.0011 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EGG10312.1 - 0.00098 18.4 0.0 0.011 14.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_24 PF13479.1 EGG10312.1 - 0.0021 17.6 0.1 0.0054 16.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EGG10312.1 - 0.0043 15.8 0.0 1.1 7.9 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 EGG10312.1 - 0.0062 16.0 0.0 0.014 14.8 0.0 1.7 1 1 0 1 1 1 1 AAA-like domain PduV-EutP PF10662.4 EGG10312.1 - 0.0073 15.7 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EGG10312.1 - 0.01 15.4 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.5 EGG10312.1 - 0.024 13.8 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Arf PF00025.16 EGG10312.1 - 0.031 13.5 0.0 0.72 9.0 0.0 2.8 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.1 EGG10312.1 - 0.032 14.2 0.0 0.073 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 EGG10312.1 - 0.038 13.6 0.0 0.086 12.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EGG10312.1 - 0.052 14.0 0.0 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein G-alpha PF00503.15 EGG10312.1 - 0.052 12.2 3.6 0.8 8.3 0.0 2.6 2 1 0 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.1 EGG10312.1 - 0.058 13.7 0.3 0.47 10.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 EGG10312.1 - 0.097 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PseudoU_synth_1 PF01416.15 EGG10313.1 - 1.1e-19 70.8 0.0 1e-12 48.3 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase Dynamitin PF04912.9 EGG10313.1 - 0.024 13.4 2.4 0.04 12.7 1.6 1.3 1 0 0 1 1 1 0 Dynamitin Ribosomal_L29 PF00831.18 EGG10313.1 - 0.15 11.7 5.0 0.094 12.4 0.8 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein DUF2011 PF09428.5 EGG10316.1 - 0.069 13.0 0.2 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) AA_permease PF00324.16 EGG10318.1 - 1.9e-120 402.4 32.9 2.3e-120 402.1 22.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGG10318.1 - 1.2e-34 119.5 35.9 1.5e-34 119.2 24.9 1.0 1 0 0 1 1 1 1 Amino acid permease HATPase_c PF02518.21 EGG10319.1 - 3.6e-30 103.9 0.0 8.1e-30 102.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGG10319.1 - 1.3e-25 89.6 0.1 7.9e-25 87.0 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EGG10319.1 - 2.2e-15 56.3 0.0 7.1e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain MHYT PF03707.11 EGG10319.1 - 1.1e-11 44.6 21.5 1.4e-06 28.2 1.4 4.2 4 0 0 4 4 4 2 Bacterial signalling protein N terminal repeat HATPase_c_3 PF13589.1 EGG10319.1 - 0.016 14.8 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rpp20 PF12328.3 EGG10320.1 - 5.4e-06 26.1 1.1 4.3e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EGG10320.1 - 4.6e-05 22.9 0.2 9.5e-05 21.9 0.1 1.6 1 0 0 1 1 1 1 Alba RP-C_C PF11800.3 EGG10320.1 - 0.15 11.7 0.6 0.17 11.5 0.4 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Cellulase PF00150.13 EGG10321.1 - 1.1e-43 149.4 0.1 1.6e-43 148.9 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CTD_bind PF04818.8 EGG10322.1 - 0.047 13.9 0.0 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase II-binding domain. DUF566 PF04484.7 EGG10326.1 - 2.4 7.5 12.7 3.4 7.0 8.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) KH_3 PF13014.1 EGG10328.1 - 1.2e-06 28.0 0.3 0.0013 18.3 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_1 PF00013.24 EGG10328.1 - 1.8e-06 27.5 0.0 0.0022 17.5 0.0 2.3 2 0 0 2 2 2 2 KH domain NUDIX PF00293.23 EGG10329.1 - 9.8e-29 99.7 0.0 1.6e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain BTD PF09270.5 EGG10331.1 - 9.1e-27 93.7 0.0 1.7e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 EGG10331.1 - 5.1e-07 30.2 0.0 9.8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 LAG1, DNA binding Mito_carr PF00153.22 EGG10332.1 - 9.6e-60 198.3 0.0 7.6e-18 64.0 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein Peptidase_M48 PF01435.13 EGG10334.1 - 5e-39 134.1 0.0 7.7e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF955 PF06114.8 EGG10334.1 - 0.021 14.5 0.0 0.093 12.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF955) Peptidase_M56 PF05569.6 EGG10334.1 - 0.05 12.5 0.2 0.16 10.9 0.1 1.7 1 1 0 1 1 1 0 BlaR1 peptidase M56 HMG_box PF00505.14 EGG10337.1 - 0.00013 22.1 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box RNA_pol_Rpb1_5 PF04998.12 EGG10339.1 - 5.7e-53 179.9 0.1 6.9e-53 179.6 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.12 EGG10339.1 - 3.6e-05 23.4 0.0 0.00038 20.1 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 CVNH PF08881.5 EGG10343.1 - 0.065 13.4 0.3 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 CVNH domain DAO PF01266.19 EGG10344.1 - 1.6e-43 148.9 0.0 2.3e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGG10344.1 - 0.00085 19.2 0.0 0.18 11.6 0.0 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EGG10344.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_8 PF13450.1 EGG10344.1 - 0.0036 17.2 0.0 0.0088 16.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF2281 PF10047.4 EGG10344.1 - 0.0087 16.3 0.2 0.18 12.1 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2281) Pyr_redox_3 PF13738.1 EGG10344.1 - 0.012 15.6 0.0 0.33 10.9 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.5 EGG10344.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 KR domain GIDA PF01134.17 EGG10344.1 - 0.21 10.4 0.0 0.99 8.1 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_transf_90 PF05686.7 EGG10345.1 - 1.7e-10 40.1 3.2 1.4e-07 30.5 0.1 3.2 3 1 0 3 3 3 2 Glycosyl transferase family 90 DUF3493 PF11998.3 EGG10348.1 - 0.03 14.2 1.2 0.048 13.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) IL13 PF03487.8 EGG10352.1 - 0.051 13.2 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Interleukin-13 IncA PF04156.9 EGG10353.1 - 0.00035 20.2 6.7 0.00089 18.9 4.7 1.7 1 0 0 1 1 1 1 IncA protein SPX PF03105.14 EGG10353.1 - 0.0049 16.6 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 SPX domain NPV_P10 PF05531.7 EGG10353.1 - 0.02 15.1 1.2 2.8 8.2 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-CCHC PF00098.18 EGG10353.1 - 0.047 13.6 0.3 0.093 12.6 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle COG2 PF06148.6 EGG10353.1 - 0.11 12.4 4.6 0.14 11.9 0.3 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.1 EGG10353.1 - 0.26 9.7 4.3 0.38 9.1 3.0 1.1 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 EGG10353.1 - 0.71 10.2 8.4 1.1 9.5 0.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DNA_topoisoIV PF00521.15 EGG10353.1 - 0.76 8.5 6.6 0.62 8.8 2.1 2.0 2 0 0 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A Gon7 PF08738.5 EGG10353.1 - 1.2 9.1 6.6 5.1 7.1 0.2 3.1 1 1 1 2 2 2 0 Gon7 family FlxA PF14282.1 EGG10353.1 - 1.8 8.5 9.8 0.55 10.2 1.3 2.8 1 1 1 2 2 2 0 FlxA-like protein MbeD_MobD PF04899.7 EGG10353.1 - 6.1 6.8 6.9 1.8 8.5 0.4 3.0 4 0 0 4 4 4 0 MbeD/MobD like BLOC1_2 PF10046.4 EGG10353.1 - 6.2 7.0 8.2 1 9.5 0.3 2.8 4 0 0 4 4 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phasin PF05597.6 EGG10353.1 - 6.9 6.4 7.8 12 5.6 1.8 2.8 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Sad1_UNC PF07738.8 EGG10355.1 - 3.1e-29 101.4 0.0 5.9e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal EF-hand_7 PF13499.1 EGG10357.1 - 3.4e-17 62.3 0.1 2e-10 40.6 0.1 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EGG10357.1 - 1.2e-15 55.4 1.8 1e-05 24.4 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EGG10357.1 - 7.5e-15 53.4 1.9 7.9e-06 25.3 0.1 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 EGG10357.1 - 2.5e-10 39.7 1.4 7.6e-06 25.4 0.1 3.8 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EGG10357.1 - 1.6e-07 31.1 0.0 0.0014 18.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EGG10357.1 - 3.1e-07 29.4 0.4 0.00083 18.6 0.0 3.4 3 0 0 3 3 3 2 EF hand EFhand_Ca_insen PF08726.5 EGG10357.1 - 0.00058 19.7 0.0 0.003 17.4 0.0 2.1 2 0 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 EGG10357.1 - 0.0033 17.0 0.0 0.08 12.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Aa_trans PF01490.13 EGG10358.1 - 9.8e-51 172.5 23.5 2.5e-50 171.1 16.3 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EGG10358.1 - 0.034 12.9 20.0 0.011 14.6 7.5 2.2 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family DUF974 PF06159.8 EGG10361.1 - 3.1e-46 157.8 0.1 4.3e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) TFIIS_M PF07500.9 EGG10362.1 - 3.9e-28 97.8 0.3 6.9e-28 97.0 0.2 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EGG10362.1 - 2.5e-12 46.2 2.9 4.1e-12 45.5 2.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EGG10362.1 - 3e-11 42.6 1.0 4.7e-11 42.0 0.7 1.3 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Solute_trans_a PF03619.11 EGG10363.1 - 9.1e-73 244.9 16.2 1.1e-72 244.6 11.2 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha TPR_11 PF13414.1 EGG10365.1 - 1.5e-06 27.7 7.3 0.02 14.5 0.0 4.1 3 1 0 3 3 3 2 TPR repeat TPR_17 PF13431.1 EGG10365.1 - 2.5e-05 24.1 1.0 0.55 10.5 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGG10365.1 - 3.1e-05 24.2 3.5 0.46 10.8 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGG10365.1 - 0.0018 18.7 6.3 4.1 8.3 0.1 5.9 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGG10365.1 - 0.0036 16.8 0.6 1.3 8.7 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGG10365.1 - 0.02 14.6 2.0 9.2 6.3 0.2 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGG10365.1 - 0.051 13.4 7.0 1.6 8.8 0.1 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGG10365.1 - 0.11 13.2 4.2 10 6.9 0.4 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Pheromone PF08015.6 EGG10367.1 - 0.022 15.5 3.3 1.5 9.7 0.0 2.4 1 1 1 2 2 2 0 Fungal mating-type pheromone RRM_6 PF14259.1 EGG10368.1 - 3.3e-28 97.4 0.6 5.8e-07 29.3 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGG10368.1 - 3.1e-26 90.7 3.9 1.4e-08 34.2 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG10368.1 - 1.7e-19 69.3 0.1 4.2e-05 23.2 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGG10368.1 - 0.001 18.8 0.5 0.26 11.1 0.2 2.6 2 0 0 2 2 2 1 RNA binding motif DUF1866 PF08952.6 EGG10368.1 - 0.0013 18.2 0.1 3.3 7.2 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.1 EGG10368.1 - 0.0034 17.1 0.0 1.6 8.5 0.0 3.4 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.1 EGG10368.1 - 0.011 15.2 0.0 5.1 6.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) DUF4651 PF15513.1 EGG10368.1 - 0.073 12.5 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) RRM_1 PF00076.17 EGG10369.1 - 6.7e-07 28.8 0.9 1.1e-06 28.2 0.6 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RasGEF PF00617.14 EGG10369.1 - 2.1e-05 24.3 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RRM_5 PF13893.1 EGG10369.1 - 0.00023 20.9 0.4 0.0012 18.6 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG10369.1 - 0.0015 18.4 0.1 0.0037 17.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGG10369.1 - 0.042 13.6 0.3 0.068 13.0 0.2 1.2 1 0 0 1 1 1 0 RNA binding motif G10 PF01125.12 EGG10371.1 - 3.4e-62 208.2 2.9 3.8e-62 208.1 2.0 1.0 1 0 0 1 1 1 1 G10 protein DNA_RNApol_7kD PF03604.8 EGG10371.1 - 0.36 10.3 9.4 0.31 10.5 3.3 2.3 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit adh_short PF00106.20 EGG10373.1 - 1.8e-12 47.5 0.0 2.3e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG10373.1 - 0.0028 17.3 0.1 0.0053 16.4 0.1 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGG10373.1 - 0.097 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Pantoate_transf PF02548.10 EGG10374.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase U1snRNP70_N PF12220.3 EGG10375.1 - 0.41 10.9 7.3 0.16 12.3 1.2 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ETRAMP PF09716.5 EGG10375.1 - 1.4 8.8 5.6 3.6 7.6 3.9 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DSBA PF01323.15 EGG10376.1 - 7.5e-23 81.0 0.0 8.9e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain PLDc_2 PF13091.1 EGG10378.1 - 1.9e-12 47.0 0.0 4.4e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EGG10378.1 - 0.001 18.7 2.7 1.4 8.8 0.0 3.5 3 0 0 3 3 3 2 Phospholipase D Active site motif tRNA-synt_2 PF00152.15 EGG10379.1 - 1.9e-67 227.4 0.0 3e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGG10379.1 - 9.4e-12 44.6 0.0 2.1e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4407 PF14362.1 EGG10379.1 - 0.1 11.5 0.9 0.15 10.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) adh_short PF00106.20 EGG10382.1 - 1.8e-11 44.2 0.2 1.2e-07 31.7 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EGG10382.1 - 0.014 15.0 0.1 0.087 12.4 0.0 1.9 2 0 0 2 2 2 0 KR domain Mucin PF01456.12 EGG10383.1 - 0.04 13.6 16.7 0.05 13.3 11.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein BAT2_N PF07001.6 EGG10383.1 - 0.081 13.2 3.7 0.092 13.0 2.5 1.0 1 0 0 1 1 1 0 BAT2 N-terminus Lectin_N PF03954.9 EGG10383.1 - 1.7 8.0 4.8 2.6 7.4 3.3 1.7 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain MSA-2c PF12238.3 EGG10383.1 - 2.1 7.9 5.1 2.5 7.7 3.6 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c CcoS PF03597.10 EGG10385.1 - 0.12 11.9 1.0 0.2 11.1 0.7 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Oxidored_FMN PF00724.15 EGG10388.1 - 5.1e-43 147.3 0.0 6.2e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3043 PF11241.3 EGG10389.1 - 3.9 7.0 5.6 16 5.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Chitin_synth_1 PF01644.12 EGG10391.1 - 7.3e-85 282.7 0.1 1.2e-84 282.0 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EGG10391.1 - 1.4e-27 96.3 0.6 2.3e-20 72.4 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EGG10391.1 - 1.8e-25 88.4 0.1 5.4e-25 86.8 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.1 EGG10391.1 - 2.3e-07 30.8 0.0 4.7e-07 29.8 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGG10391.1 - 0.00025 20.8 12.5 0.00025 20.8 8.6 3.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF3989 PF13150.1 EGG10391.1 - 1.9 7.9 4.9 0.62 9.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) p450 PF00067.17 EGG10395.1 - 9.4e-64 215.6 0.0 1.2e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YbjQ_1 PF01906.12 EGG10396.1 - 0.022 15.1 0.0 0.076 13.4 0.0 2.0 1 0 0 1 1 1 0 Putative heavy-metal-binding Glyco_hydro_25 PF01183.15 EGG10399.1 - 0.044 13.5 0.2 0.049 13.4 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 25 DUF605 PF04652.11 EGG10400.1 - 7.4 5.8 17.1 9.1 5.5 11.9 1.1 1 0 0 1 1 1 0 Vta1 like DUF555 PF04475.7 EGG10401.1 - 0.13 12.2 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF555) Pkinase PF00069.20 EGG10403.1 - 1.3e-71 240.7 0.0 1.7e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG10403.1 - 1.2e-31 109.7 0.0 1.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGG10403.1 - 1e-11 45.1 3.2 2.5e-11 43.9 2.2 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGG10403.1 - 6.8e-05 21.9 0.0 0.00019 20.5 0.0 1.6 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EGG10403.1 - 0.043 13.5 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGG10403.1 - 0.062 12.3 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP70 PF00012.15 EGG10404.1 - 3.6e-156 520.5 0.7 4.1e-156 520.4 0.0 1.3 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EGG10404.1 - 4.7e-12 45.1 0.0 1.4e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.3 EGG10404.1 - 0.0052 15.7 0.0 0.023 13.5 0.0 2.1 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; His_biosynth PF00977.16 EGG10407.1 - 6.4e-43 146.6 0.1 2.4e-41 141.5 0.1 2.7 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EGG10407.1 - 2.9e-27 95.3 0.0 4.7e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EGG10407.1 - 1.4e-09 37.7 0.0 2.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 EGG10407.1 - 9.2e-07 28.6 0.0 1.2e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 EGG10407.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase C26 Dus PF01207.12 EGG10407.1 - 0.023 13.5 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 EGG10407.1 - 0.026 13.6 0.0 1.2 8.2 0.0 2.9 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI ATP-synt_C PF00137.16 EGG10408.1 - 1.4e-25 88.9 26.9 2e-18 66.0 7.0 2.3 2 1 0 2 2 2 2 ATP synthase subunit C Abhydrolase_6 PF12697.2 EGG10409.1 - 1e-21 77.8 0.0 1.4e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG10409.1 - 7e-19 68.0 0.0 1.3e-18 67.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGG10409.1 - 1.1e-17 63.6 0.0 2e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EGG10409.1 - 7.7e-07 28.8 0.0 4.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGG10409.1 - 3.8e-06 26.2 0.7 0.0022 17.2 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EGG10409.1 - 0.0026 17.2 0.1 0.35 10.2 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 EGG10409.1 - 0.0029 16.9 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family PGAP1 PF07819.8 EGG10409.1 - 0.0057 16.2 0.0 0.014 15.0 0.0 1.6 2 1 0 2 2 2 1 PGAP1-like protein LCAT PF02450.10 EGG10409.1 - 0.0058 15.6 0.0 0.0094 14.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase AXE1 PF05448.7 EGG10409.1 - 0.029 12.8 1.0 0.48 8.8 0.0 2.6 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 EGG10409.1 - 0.03 13.2 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme FSH1 PF03959.8 EGG10409.1 - 0.036 13.4 0.1 0.13 11.6 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF1749 PF08538.5 EGG10409.1 - 0.055 12.3 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Esterase PF00756.15 EGG10409.1 - 0.11 11.9 0.0 4.8 6.5 0.0 2.3 2 1 0 2 2 2 0 Putative esterase Abhydrolase_3 PF07859.8 EGG10409.1 - 0.12 11.9 0.1 0.27 10.7 0.0 1.7 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF202 PF02656.10 EGG10410.1 - 2.7e-19 69.1 0.2 6.8e-19 67.8 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF202) UPF0233 PF06781.7 EGG10410.1 - 0.015 14.8 0.0 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) DUF3611 PF12263.3 EGG10410.1 - 0.15 11.4 2.9 0.26 10.6 0.7 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3611) FlxA PF14282.1 EGG10411.1 - 0.00089 19.1 1.9 0.0015 18.4 1.3 1.3 1 0 0 1 1 1 1 FlxA-like protein DUF2317 PF10079.4 EGG10411.1 - 0.0068 15.0 0.3 0.0098 14.5 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2317) Sin3_corepress PF08295.7 EGG10411.1 - 0.0095 15.6 1.4 0.025 14.3 0.9 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor IncA PF04156.9 EGG10411.1 - 0.015 14.8 4.8 0.025 14.1 3.3 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EGG10411.1 - 0.28 8.9 2.3 0.39 8.5 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 EGG10411.1 - 0.8 9.9 3.8 11 6.4 2.5 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SET PF00856.23 EGG10415.1 - 0.04 14.2 0.0 0.43 10.8 0.0 2.2 1 1 0 1 1 1 0 SET domain Cellulase PF00150.13 EGG10416.1 - 4.7e-07 29.2 0.0 8.5e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GRA6 PF05084.8 EGG10416.1 - 8.9e-05 22.1 0.6 0.00015 21.3 0.4 1.3 1 0 0 1 1 1 1 Granule antigen protein (GRA6) DUF3357 PF11837.3 EGG10416.1 - 0.011 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) ETRAMP PF09716.5 EGG10416.1 - 0.14 12.1 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Abhydrolase_2 PF02230.11 EGG10418.1 - 1.8e-27 96.2 0.0 6.2e-27 94.4 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGG10418.1 - 2.9e-05 23.8 0.0 0.00012 21.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG10418.1 - 0.00025 21.0 0.0 0.0026 17.6 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGG10418.1 - 0.035 13.5 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF4634 PF15465.1 EGG10419.1 - 0.09 12.9 0.3 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) Zn_clus PF00172.13 EGG10420.1 - 0.0028 17.5 11.3 0.0059 16.4 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EGG10420.1 - 0.0034 17.1 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EGG10420.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 PAS domain DUF3729 PF12526.3 EGG10421.1 - 0.34 12.2 7.4 0.2 12.9 2.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3729) Sugar_tr PF00083.19 EGG10422.1 - 1.9e-34 119.0 34.4 7.3e-21 74.2 7.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGG10422.1 - 5.9e-18 64.6 67.6 1.1e-16 60.5 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF843 PF05814.6 EGG10422.1 - 0.026 14.2 1.0 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) DUF3226 PF11536.3 EGG10422.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Mannosyl_trans2 PF04188.8 EGG10423.1 - 3.7e-16 59.1 1.7 4e-16 58.9 1.2 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) Methylase_S PF01420.14 EGG10424.1 - 0.089 12.7 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain DUF1533 PF07550.6 EGG10426.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) Ras PF00071.17 EGG10427.1 - 4.4e-39 133.4 0.0 5e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG10427.1 - 2.1e-08 34.6 0.0 2.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG10427.1 - 0.0041 16.3 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF1729 PF08354.5 EGG10429.1 - 4.6e-28 96.7 0.8 1.1e-27 95.6 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) NMO PF03060.10 EGG10429.1 - 0.015 14.4 0.0 3.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Nitronate monooxygenase Acyl_transf_1 PF00698.16 EGG10429.1 - 0.02 14.2 0.1 3.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Acyl transferase domain TMEM61 PF15105.1 EGG10429.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 TMEM61 protein family Pox_P4A PF03395.9 EGG10429.1 - 0.31 8.5 0.9 0.46 7.9 0.6 1.1 1 0 0 1 1 1 0 Poxvirus P4A protein Eaf7 PF07904.8 EGG10430.1 - 0.15 12.0 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 MBOAT_2 PF13813.1 EGG10431.1 - 3e-10 40.0 2.8 3e-10 40.0 2.0 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Mito_carr PF00153.22 EGG10432.1 - 7.2e-56 185.8 3.6 1.4e-23 82.3 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein YukD PF08817.5 EGG10432.1 - 0.035 14.6 0.0 0.065 13.8 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD AAA_2 PF07724.9 EGG10433.1 - 2.8e-52 177.0 0.3 2.6e-46 157.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EGG10433.1 - 1.4e-21 76.1 3.6 3.7e-21 74.7 1.5 2.6 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EGG10433.1 - 1.9e-21 76.6 2.7 9.2e-11 42.0 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGG10433.1 - 5e-18 65.1 0.1 3.4e-12 46.2 0.0 3.4 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGG10433.1 - 3.3e-13 50.0 2.3 0.00027 20.9 0.0 4.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EGG10433.1 - 8.1e-13 48.6 0.8 0.00029 20.9 0.0 4.2 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EGG10433.1 - 3.1e-11 43.0 0.3 3e-07 30.0 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_14 PF13173.1 EGG10433.1 - 7.8e-10 38.7 1.3 6.4e-05 22.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 EGG10433.1 - 3.3e-08 33.5 4.8 0.00054 19.7 0.1 4.5 2 1 0 3 3 3 1 Archaeal ATPase DNA_pol3_delta2 PF13177.1 EGG10433.1 - 4.4e-07 29.7 0.1 2.7e-05 23.9 0.0 2.9 3 0 0 3 3 2 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 EGG10433.1 - 8.4e-07 29.8 3.3 0.017 15.9 0.1 3.9 3 1 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EGG10433.1 - 1.3e-06 27.9 0.1 0.063 12.6 0.1 2.9 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EGG10433.1 - 1.5e-05 25.3 6.8 0.034 14.4 0.0 4.3 4 1 1 5 5 4 2 AAA domain RNA_helicase PF00910.17 EGG10433.1 - 1.5e-05 25.0 0.0 0.27 11.4 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.16 EGG10433.1 - 5.5e-05 22.4 0.8 0.72 8.9 0.0 3.5 3 1 0 4 4 3 2 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.12 EGG10433.1 - 0.00017 21.2 0.0 0.05 13.1 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MobB PF03205.9 EGG10433.1 - 0.00022 20.9 0.0 0.42 10.2 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EGG10433.1 - 0.00029 21.1 2.0 0.1 12.8 0.0 3.7 3 0 0 3 3 3 1 ABC transporter HAUS2 PF15003.1 EGG10433.1 - 0.00034 19.7 1.5 0.00074 18.6 1.0 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 DUF258 PF03193.11 EGG10433.1 - 0.00037 19.7 0.0 0.92 8.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 EGG10433.1 - 0.00045 20.2 0.0 1.5 8.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EGG10433.1 - 0.0005 19.7 0.0 0.14 11.8 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_29 PF13555.1 EGG10433.1 - 0.00065 19.1 0.0 0.81 9.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RuvB_N PF05496.7 EGG10433.1 - 0.00085 18.4 1.2 1.9 7.4 0.5 3.2 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus PduV-EutP PF10662.4 EGG10433.1 - 0.0015 18.0 0.0 1.6 8.2 0.0 3.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EGG10433.1 - 0.0018 17.8 0.0 0.25 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EGG10433.1 - 0.0019 17.2 1.4 2 7.2 0.0 3.5 3 1 0 3 3 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EGG10433.1 - 0.0025 17.5 0.0 0.29 10.9 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain SRP54 PF00448.17 EGG10433.1 - 0.0036 16.7 0.0 1.2 8.5 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EGG10433.1 - 0.0038 16.6 0.1 6 6.2 0.0 3.4 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.1 EGG10433.1 - 0.0048 16.4 0.0 0.82 9.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EGG10433.1 - 0.0064 16.8 0.5 0.0064 16.8 0.3 4.3 2 2 0 2 2 1 1 AAA domain TrwB_AAD_bind PF10412.4 EGG10433.1 - 0.014 14.0 0.2 2.2 6.8 0.0 3.0 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.10 EGG10433.1 - 0.015 15.1 4.6 1.1 9.0 0.1 3.9 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit IncA PF04156.9 EGG10433.1 - 0.015 14.9 9.7 0.055 13.0 6.7 2.0 1 0 0 1 1 1 0 IncA protein Miro PF08477.8 EGG10433.1 - 0.018 15.5 0.6 6.3 7.3 0.0 3.6 3 0 0 3 3 3 0 Miro-like protein PhoH PF02562.11 EGG10433.1 - 0.021 14.0 0.1 1.3 8.2 0.0 2.7 3 0 0 3 3 2 0 PhoH-like protein UPF0079 PF02367.12 EGG10433.1 - 0.023 14.3 0.0 8 6.1 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF4624 PF15417.1 EGG10433.1 - 0.026 14.1 1.5 0.049 13.2 0.3 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4624) AAA_33 PF13671.1 EGG10433.1 - 0.037 13.8 0.0 10 6.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGG10433.1 - 0.11 11.8 7.9 0.36 10.2 0.1 3.4 3 2 0 3 3 3 0 AAA-like domain V_ATPase_I PF01496.14 EGG10433.1 - 0.14 10.0 6.8 0.22 9.3 4.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_3 PF07726.6 EGG10433.1 - 0.16 11.5 2.1 1.3 8.6 0.1 3.2 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Cob_adeno_trans PF01923.13 EGG10433.1 - 0.37 10.5 7.0 0.9 9.3 1.1 3.1 2 1 1 3 3 3 0 Cobalamin adenosyltransferase CHD5 PF04420.9 EGG10433.1 - 1.1 8.9 4.5 2.4 7.7 3.2 1.5 1 0 0 1 1 1 0 CHD5-like protein FlxA PF14282.1 EGG10433.1 - 1.8 8.5 10.9 5.2 7.0 7.2 2.0 1 1 0 1 1 1 0 FlxA-like protein ADH_zinc_N PF00107.21 EGG10434.1 - 7e-27 93.5 0.0 1.4e-26 92.5 0.0 1.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGG10434.1 - 5.2e-09 35.8 0.0 4.5e-07 29.5 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGG10434.1 - 0.00037 21.3 0.0 0.00069 20.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 EGG10434.1 - 0.043 13.6 0.4 0.081 12.7 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2493 PF10686.4 EGG10434.1 - 0.083 12.4 0.2 0.17 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) NAD_binding_5 PF07994.7 EGG10436.1 - 0.097 12.1 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Tim44 PF04280.10 EGG10436.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Tim44-like domain RskA PF10099.4 EGG10437.1 - 0.00057 19.6 0.1 0.00072 19.3 0.1 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Bax1-I PF01027.15 EGG10438.1 - 0.0083 15.7 0.5 0.0083 15.7 0.4 1.6 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Amastin PF07344.6 EGG10438.1 - 0.023 14.2 0.3 0.023 14.2 0.2 2.1 2 1 2 4 4 4 0 Amastin surface glycoprotein DUF4199 PF13858.1 EGG10438.1 - 0.074 12.9 1.7 0.16 11.9 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) DUF417 PF04224.7 EGG10438.1 - 0.075 12.3 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF417 MFS_1 PF07690.11 EGG10439.1 - 0.0026 16.5 10.0 0.0026 16.5 6.9 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily IgaA PF07095.6 EGG10439.1 - 0.035 11.8 0.7 0.05 11.3 0.5 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Cadherin PF00028.12 EGG10439.1 - 0.1 12.8 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Cadherin domain MFS_1 PF07690.11 EGG10440.1 - 5.3e-15 54.9 24.2 1e-14 54.0 16.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily IgaA PF07095.6 EGG10440.1 - 0.054 11.2 0.7 0.077 10.7 0.5 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Ldh_1_N PF00056.18 EGG10441.1 - 2e-09 37.3 0.0 8.3e-08 32.1 0.0 2.0 1 1 1 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EGG10442.1 - 1.2e-33 116.3 0.0 3.1e-33 114.9 0.0 1.7 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EGG10442.1 - 1.6e-23 83.0 0.1 1.9e-22 79.5 0.0 2.1 1 1 1 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 EGG10442.1 - 0.1 11.9 0.1 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase DUF1212 PF06738.7 EGG10445.1 - 1.1e-31 109.7 3.0 1.1e-31 109.7 2.1 2.7 2 1 2 4 4 4 3 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EGG10445.1 - 6.9e-23 81.0 11.7 6.9e-23 81.0 8.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) DUF4574 PF15141.1 EGG10445.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) DUF2301 PF10063.4 EGG10445.1 - 3.3 7.9 8.2 0.48 10.6 1.6 2.5 2 1 1 3 3 3 0 Uncharacterized integral membrane protein (DUF2301) Oxidored_q1 PF00361.15 EGG10446.1 - 0.0064 15.7 3.5 0.0076 15.5 2.5 1.1 1 0 0 1 1 1 1 NADH-Ubiquinone/plastoquinone (complex I), various chains PalH PF08733.5 EGG10446.1 - 0.038 12.8 0.4 0.044 12.6 0.3 1.1 1 0 0 1 1 1 0 PalH/RIM21 DUF4234 PF14018.1 EGG10446.1 - 0.17 11.6 0.5 0.54 10.0 0.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) tRNA_U5-meth_tr PF05958.6 EGG10447.1 - 4.5e-23 81.5 0.3 4e-21 75.1 0.1 3.2 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EGG10447.1 - 1.3e-08 34.5 0.0 3.1e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 EGG10447.1 - 2.8e-08 33.5 0.0 5.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EGG10447.1 - 5.9e-07 30.0 0.0 1.3e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG10447.1 - 5.7e-05 23.1 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGG10447.1 - 0.00042 19.4 0.0 0.00093 18.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Met_10 PF02475.11 EGG10447.1 - 0.00058 19.5 0.1 0.005 16.4 0.0 2.3 2 1 1 3 3 3 1 Met-10+ like-protein MTS PF05175.9 EGG10447.1 - 0.00092 18.6 0.0 0.0019 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EGG10447.1 - 0.0015 17.7 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EGG10447.1 - 0.0018 18.7 0.0 0.0053 17.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 EGG10447.1 - 0.028 13.9 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 EGG10447.1 - 0.071 12.2 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TRM PF02005.11 EGG10447.1 - 0.09 11.6 0.2 0.21 10.4 0.0 1.6 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase RdRP PF05183.7 EGG10451.1 - 2.2e-66 224.8 0.0 6.4e-56 190.2 0.0 3.3 2 1 1 3 3 3 3 RNA dependent RNA polymerase 60KD_IMP PF02096.15 EGG10451.1 - 0.013 15.2 0.4 0.024 14.2 0.3 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein zf-RING_2 PF13639.1 EGG10453.1 - 0.2 11.5 19.2 0.059 13.2 9.7 2.2 2 0 0 2 2 2 0 Ring finger domain Rad50_zn_hook PF04423.9 EGG10453.1 - 0.44 10.0 3.9 1.7 8.1 0.7 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF230 PF03003.11 EGG10453.1 - 9.7 5.7 14.2 12 5.4 9.9 1.2 1 0 0 1 1 1 0 Poxvirus proteins of unknown function Palm_thioest PF02089.10 EGG10454.1 - 6.8e-51 172.8 0.0 1.5e-32 112.7 0.0 2.0 1 1 1 2 2 2 2 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 EGG10454.1 - 6.8e-06 26.1 0.0 8.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG10454.1 - 0.0024 17.4 0.0 0.0051 16.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EGG10454.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Baculo_PEP_C PF04513.7 EGG10455.1 - 0.013 15.3 4.3 0.27 11.0 0.1 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus EURL PF06937.6 EGG10455.1 - 0.016 14.6 0.2 0.038 13.3 0.2 1.6 1 0 0 1 1 1 0 EURL protein PCP PF02429.10 EGG10455.1 - 0.02 15.0 0.1 0.02 15.0 0.1 2.9 3 1 1 4 4 4 0 Peridinin-chlorophyll A binding protein Lipoprotein_10 PF03202.8 EGG10455.1 - 1.8 8.5 5.2 1.6 8.7 0.4 2.3 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region Ribosomal_S2 PF00318.15 EGG10456.1 - 2.9e-42 144.2 0.1 6e-22 77.9 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 BTG PF07742.7 EGG10458.1 - 5.5e-12 45.2 0.0 1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 BTG family Ig_2 PF13895.1 EGG10458.1 - 0.014 15.5 0.2 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 Immunoglobulin domain DUF4206 PF13901.1 EGG10459.1 - 0.19 11.2 2.9 0.41 10.1 1.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4206) Baculo_PEP_C PF04513.7 EGG10459.1 - 2.1 8.1 12.3 0.037 13.8 2.6 2.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.20 EGG10460.1 - 2.1e-24 86.0 0.0 2.6e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG10460.1 - 2.3e-08 33.4 0.0 2.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG10460.1 - 0.0026 16.7 0.0 0.004 16.1 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGG10460.1 - 0.0052 15.8 0.0 0.0067 15.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_3 PF13456.1 EGG10461.1 - 5.2e-07 29.3 0.4 1.4e-06 27.9 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase-like Rrp15p PF07890.7 EGG10463.1 - 5.3e-17 62.0 6.3 5.3e-17 62.0 4.4 4.0 1 1 1 2 2 2 1 Rrp15p GLTSCR1 PF15249.1 EGG10463.1 - 0.6 10.2 4.4 1.8 8.6 3.0 1.8 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region Amino_oxidase PF01593.19 EGG10464.1 - 1.9e-51 175.5 0.0 1.6e-50 172.5 0.0 2.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGG10464.1 - 4.4e-14 52.2 0.0 1e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGG10464.1 - 1.5e-09 37.2 0.0 6.7e-08 31.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGG10464.1 - 7.7e-08 31.5 0.6 1.2e-07 31.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGG10464.1 - 9.2e-08 32.2 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGG10464.1 - 3.7e-07 30.4 0.0 1.2e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGG10464.1 - 1.8e-06 28.2 0.1 4e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGG10464.1 - 4.6e-06 25.9 0.0 6.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGG10464.1 - 6.4e-06 25.4 0.1 1.1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EGG10464.1 - 1.8e-05 23.8 0.0 2.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EGG10464.1 - 2.4e-05 23.0 0.5 3.6e-05 22.4 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EGG10464.1 - 0.00049 19.2 0.5 0.00088 18.4 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EGG10464.1 - 0.00088 18.2 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Shikimate_DH PF01488.15 EGG10464.1 - 0.015 15.3 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 EGG10464.1 - 0.019 14.5 0.1 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EGG10464.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 EGG10464.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EGG10464.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EGG10464.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGG10464.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 EGG10464.1 - 0.24 9.9 0.4 1.1 7.7 0.4 1.8 2 0 0 2 2 2 0 Tryptophan halogenase DUF221 PF02714.10 EGG10465.1 - 4e-12 45.6 14.8 1.1e-11 44.2 6.3 3.1 3 0 0 3 3 3 2 Domain of unknown function DUF221 SUR7 PF06687.7 EGG10466.1 - 1.6e-07 31.1 1.4 2.2e-07 30.6 1.0 1.3 1 0 0 1 1 1 1 SUR7/PalI family Alpha_kinase PF02816.13 EGG10467.1 - 1.3e-07 31.5 0.1 2.1e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family Glucan_synthase PF02364.10 EGG10469.1 - 2.9e-74 250.4 4.8 4.3e-62 210.1 1.5 3.9 1 1 1 2 2 2 2 1,3-beta-glucan synthase component DNA_pol_B_exo1 PF03104.14 EGG10470.1 - 0.11 11.3 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain CCD PF07860.6 EGG10473.1 - 4.6 6.6 7.1 0.91 8.9 1.6 2.2 2 1 1 3 3 3 0 WisP family C-Terminal Region TPR_11 PF13414.1 EGG10474.1 - 0.0013 18.2 0.4 0.016 14.8 0.1 1.9 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.1 EGG10474.1 - 0.0016 18.3 0.5 0.051 13.5 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGG10474.1 - 0.0039 17.5 1.5 1.4 9.5 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGG10474.1 - 0.023 15.0 0.1 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TRP PF06011.7 EGG10475.1 - 1.9e-51 175.0 22.6 5.6e-51 173.4 15.6 1.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGG10475.1 - 4.4e-27 94.8 0.3 7.4e-27 94.1 0.2 1.4 1 0 0 1 1 1 1 ML-like domain ERO1 PF04137.10 EGG10476.1 - 3e-120 401.5 0.7 3.8e-120 401.1 0.5 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) CLN3 PF02487.12 EGG10477.1 - 0.11 11.2 2.0 0.12 11.0 1.4 1.1 1 0 0 1 1 1 0 CLN3 protein Dioxygenase_C PF00775.16 EGG10481.1 - 1.7e-09 37.2 0.3 2.7e-08 33.2 0.2 2.2 1 1 0 1 1 1 1 Dioxygenase Dioxygenase_C PF00775.16 EGG10482.1 - 3.5e-09 36.1 0.3 1.9e-07 30.5 0.0 2.4 2 1 0 2 2 2 2 Dioxygenase PA_decarbox PF05870.6 EGG10482.1 - 0.037 13.5 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) Acetyltransf_1 PF00583.19 EGG10484.1 - 6.8e-10 38.8 0.0 9.7e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGG10484.1 - 4.7e-05 23.0 0.0 8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EGG10484.1 - 0.00037 20.5 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGG10484.1 - 0.017 15.0 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Adeno_E3_CR2 PF02439.10 EGG10485.1 - 0.005 16.3 0.4 0.0097 15.4 0.3 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EcoR124_C PF12008.3 EGG10485.1 - 0.012 14.8 0.4 0.029 13.5 0.2 1.6 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal Plasmodium_Vir PF05795.6 EGG10485.1 - 0.025 13.7 2.2 0.037 13.2 1.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein EphA2_TM PF14575.1 EGG10485.1 - 0.047 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 EGG10485.1 - 0.051 13.6 3.5 0.058 13.4 0.1 2.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EGG10485.1 - 0.17 11.5 3.7 0.59 9.7 2.5 1.8 1 1 0 1 1 1 0 Rifin/stevor family MFS_2 PF13347.1 EGG10485.1 - 4.1 5.6 9.6 7.4 4.8 6.6 1.4 1 1 0 1 1 1 0 MFS/sugar transport protein 2-Hacid_dh PF00389.25 EGG10486.1 - 0.15 11.5 4.7 0.058 12.8 0.6 2.0 1 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain RAMP PF04901.8 EGG10488.1 - 0.083 12.6 0.2 0.088 12.5 0.1 1.1 1 0 0 1 1 1 0 Receptor activity modifying family Med11 PF10280.4 EGG10489.1 - 2.1e-11 43.8 0.1 5e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Mediator complex protein Pkinase PF00069.20 EGG10491.1 - 7e-36 123.6 0.0 7.9e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG10491.1 - 1.5e-18 66.7 0.0 1.7e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG10491.1 - 7.1e-05 21.9 0.0 0.0057 15.6 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EGG10491.1 - 0.023 13.7 0.0 0.044 12.8 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Imm16 PF15565.1 EGG10491.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 16 Mito_carr PF00153.22 EGG10494.1 - 6.4e-68 224.5 0.5 7.4e-24 83.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Spermine_synth PF01564.12 EGG10495.1 - 3.8e-10 39.1 0.4 6.1e-10 38.4 0.2 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase MBOAT_2 PF13813.1 EGG10497.1 - 2e-11 43.8 2.9 2.2e-11 43.6 0.6 2.0 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family CorA PF01544.13 EGG10500.1 - 6.8e-33 113.9 12.7 3.6e-20 72.1 1.1 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein UBA PF00627.26 EGG10502.1 - 1.2e-22 79.0 2.9 9.6e-11 41.2 0.7 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.6 EGG10502.1 - 1.6e-17 62.7 12.9 3e-17 61.8 8.9 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EGG10502.1 - 1.3e-16 59.7 1.7 2.1e-16 59.0 1.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGG10502.1 - 8.4e-06 25.3 2.6 1.4e-05 24.6 1.8 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EGG10502.1 - 9.7e-05 21.8 0.3 0.31 10.6 0.0 3.2 3 0 0 3 3 3 2 Fungal ubiquitin-associated domain DUF2407 PF10302.4 EGG10502.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PRCC PF10253.4 EGG10502.1 - 2.6 8.7 11.4 1.2 9.8 1.1 2.3 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting HC2 PF07382.6 EGG10503.1 - 2.2e-06 27.7 0.0 2.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Gin PF10764.4 EGG10503.1 - 7 6.4 11.2 32 4.3 0.3 5.0 2 1 3 5 5 5 0 Inhibitor of sigma-G Gin DNA_pol_phi PF04931.8 EGG10504.1 - 0.13 10.0 0.0 0.14 9.9 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Med15 PF09606.5 EGG10505.1 - 3.8 5.5 53.1 4.5 5.3 36.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-C2H2 PF00096.21 EGG10506.1 - 2.7e-13 49.3 14.2 1.8e-05 24.8 0.5 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG10506.1 - 6e-10 38.9 13.2 0.00047 20.3 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGG10506.1 - 3.4e-09 36.4 13.1 0.001 19.2 0.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGG10506.1 - 4e-05 23.3 5.0 0.11 12.4 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EGG10506.1 - 0.0045 17.1 2.4 1.8 8.8 0.1 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type C1_4 PF07975.7 EGG10506.1 - 0.036 14.0 2.6 2.8 8.0 0.4 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.3 EGG10506.1 - 0.041 14.0 0.3 0.041 14.0 0.2 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding KAR9 PF08580.5 EGG10506.1 - 0.088 11.0 3.3 0.12 10.5 2.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Cript PF10235.4 EGG10506.1 - 0.089 13.1 6.9 0.4 11.0 0.6 2.8 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT Nup160 PF11715.3 EGG10506.1 - 0.11 10.6 0.6 0.4 8.7 0.1 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 zf-met2 PF12907.2 EGG10506.1 - 0.18 11.7 1.4 2.8 7.9 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding zf-C2H2_2 PF12756.2 EGG10506.1 - 0.57 10.3 4.4 4.2 7.5 0.6 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 EGG10506.1 - 0.67 10.3 5.8 0.38 11.1 1.0 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger Zn-ribbon_8 PF09723.5 EGG10506.1 - 1.1 9.2 6.7 7.3 6.6 0.2 2.8 2 1 0 2 2 2 0 Zinc ribbon domain CpXC PF14353.1 EGG10506.1 - 2.6 8.0 7.2 28 4.7 1.6 2.9 2 1 1 3 3 3 0 CpXC protein WD40 PF00400.27 EGG10507.1 - 1e-16 60.0 3.9 2.8e-08 33.3 0.2 6.4 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EGG10507.1 - 0.00015 21.8 0.1 0.0017 18.5 0.0 2.5 2 0 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 EGG10507.1 - 0.0016 16.8 0.0 0.43 8.8 0.0 2.7 2 1 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 EGG10507.1 - 0.0073 15.7 0.5 0.032 13.6 0.4 1.9 1 1 0 1 1 1 1 PQQ-like domain eIF2A PF08662.6 EGG10507.1 - 0.027 14.2 0.0 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EGG10507.1 - 0.079 11.1 0.0 0.19 9.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) PV-1 PF06637.6 EGG10509.1 - 0.15 10.5 14.4 0.21 10.1 10.0 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) CPSase_L_D2 PF02786.12 EGG10511.1 - 3.6e-73 245.3 0.0 5.6e-73 244.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EGG10511.1 - 4e-36 123.4 0.0 8.3e-36 122.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGG10511.1 - 1.1e-32 112.1 0.0 2.2e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EGG10511.1 - 2.2e-15 56.0 6.7 2.4e-15 55.9 3.1 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EGG10511.1 - 2.7e-14 52.6 0.0 1.6e-13 50.0 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EGG10511.1 - 1.6e-13 50.8 0.0 3.4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGG10511.1 - 1e-11 44.6 0.0 2.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EGG10511.1 - 6.4e-08 32.1 0.0 1.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGG10511.1 - 0.00023 21.0 0.0 0.00053 19.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EGG10511.1 - 0.00093 18.8 3.3 0.13 11.9 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like GARS_A PF01071.14 EGG10511.1 - 0.0026 17.3 0.2 0.007 15.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.1 EGG10511.1 - 0.0046 17.2 0.3 0.037 14.3 0.0 2.5 2 0 0 2 2 2 1 HlyD family secretion protein NQRA PF05896.6 EGG10511.1 - 0.042 13.0 0.5 0.079 12.1 0.4 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Transp_cyt_pur PF02133.10 EGG10512.1 - 2.2e-100 336.2 25.5 2.5e-100 336.1 17.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin F-box-like PF12937.2 EGG10513.1 - 8.4e-05 22.2 1.8 8.4e-05 22.2 1.3 2.8 3 1 0 3 3 3 1 F-box-like F-box PF00646.28 EGG10513.1 - 0.00058 19.4 1.6 0.78 9.4 0.2 3.4 3 0 0 3 3 3 2 F-box domain LRR_4 PF12799.2 EGG10513.1 - 0.017 14.7 7.6 1.2 8.8 1.0 4.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG10513.1 - 3.4 7.5 7.2 10 5.9 2.9 3.2 2 1 2 4 4 4 0 Leucine rich repeat TBPIP PF07106.8 EGG10514.1 - 9.7e-27 93.5 14.7 9.7e-27 93.5 10.2 2.2 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 EGG10514.1 - 3.8e-05 23.4 9.8 3.8e-05 23.4 6.8 2.2 1 1 1 2 2 2 1 Mnd1 family CAP_N PF01213.14 EGG10514.1 - 0.012 14.8 3.5 0.016 14.5 0.1 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DegS PF05384.6 EGG10514.1 - 0.053 12.7 14.2 0.008 15.4 4.8 2.4 2 1 0 2 2 2 0 Sensor protein DegS DUF1822 PF08852.6 EGG10514.1 - 0.062 12.0 10.8 0.075 11.8 7.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1822) BRX_N PF13713.1 EGG10514.1 - 0.12 11.8 3.1 10 5.6 0.1 2.7 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain SLY PF12485.3 EGG10514.1 - 0.25 11.5 4.8 0.12 12.6 1.5 1.8 1 1 0 1 1 1 0 Lymphocyte signaling adaptor protein IncA PF04156.9 EGG10514.1 - 1.5 8.3 24.0 15 5.1 14.4 2.5 1 1 1 2 2 2 0 IncA protein FlgN PF05130.7 EGG10514.1 - 2.4 8.4 16.8 7.7 6.7 3.5 3.0 1 1 1 2 2 2 0 FlgN protein NYD-SP28_assoc PF14775.1 EGG10514.1 - 9.9 5.9 8.7 2.4 7.9 0.4 2.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain SNF2_N PF00176.18 EGG10515.1 - 1.1e-60 204.9 0.2 1.7e-60 204.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGG10515.1 - 2.1e-12 46.6 0.0 5.5e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGG10515.1 - 2.1e-05 24.0 0.0 0.00023 20.6 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 EGG10515.1 - 4.2e-05 23.4 0.0 0.0005 19.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4218 PF13960.1 EGG10516.1 - 0.093 12.1 0.0 0.3 10.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4218) DUF1962 PF09227.5 EGG10517.1 - 0.021 14.8 2.9 0.021 14.8 2.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1962) Alpha-amylase PF00128.19 EGG10518.1 - 2.1e-33 116.0 0.7 1e-32 113.8 0.4 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.5 EGG10518.1 - 1.4e-07 31.2 1.1 4.7e-07 29.6 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.11 EGG10518.1 - 0.0066 14.2 0.0 0.41 8.3 0.0 2.7 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 FAM176 PF14851.1 EGG10519.1 - 1.5 8.4 9.3 0.14 11.7 1.2 2.3 2 0 0 2 2 2 0 FAM176 family vMSA PF00695.14 EGG10519.1 - 4.7 6.3 5.2 6.3 5.8 3.6 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus MFS_1 PF07690.11 EGG10520.1 - 9.2e-30 103.5 39.1 2.6e-29 102.0 27.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EGG10520.1 - 0.025 14.9 0.4 0.11 12.9 0.1 2.2 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TMEM18 PF14770.1 EGG10520.1 - 9.1 5.8 16.6 0.14 11.7 0.2 4.1 2 1 0 3 3 3 0 Transmembrane protein 18 BCDHK_Adom3 PF10436.4 EGG10521.1 - 1.6e-12 47.2 0.0 1.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase YmdB PF13277.1 EGG10521.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 YmdB-like protein DUF986 PF06173.7 EGG10521.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF986) Ndc1_Nup PF09531.5 EGG10523.1 - 1.9 6.8 19.9 0.014 13.8 6.7 1.9 1 1 1 2 2 2 0 Nucleoporin protein Ndc1-Nup CENP-B_dimeris PF09026.5 EGG10523.1 - 3 8.1 12.9 2.5 8.3 2.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PLA2_B PF01735.13 EGG10524.1 - 4.9e-82 275.6 0.8 6.3e-82 275.3 0.5 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.17 EGG10524.1 - 0.052 13.4 0.6 0.065 13.1 0.4 1.4 1 1 0 1 1 1 0 Patatin-like phospholipase Pantoate_transf PF02548.10 EGG10525.1 - 1e-70 237.8 0.0 1.9e-65 220.5 0.0 2.8 2 1 0 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EGG10525.1 - 0.061 12.5 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase tRNA-synt_1 PF00133.17 EGG10526.1 - 4.5e-218 725.1 0.0 6.7e-218 724.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGG10526.1 - 4.5e-26 91.4 0.0 9.6e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGG10526.1 - 9.5e-17 60.7 1.1 1.2e-06 27.4 0.1 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EGG10526.1 - 0.0019 17.3 0.0 0.034 13.2 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain BRE1 PF08647.6 EGG10527.1 - 1.3e-12 47.4 9.2 1.3e-12 47.4 6.4 6.6 4 2 4 8 8 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.20 EGG10527.1 - 7.3e-07 28.7 12.0 1.3e-06 27.9 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG10527.1 - 1.9e-06 27.7 11.7 3.5e-06 26.9 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG10527.1 - 3.8e-06 26.4 10.2 6.7e-06 25.6 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG10527.1 - 4.4e-06 26.3 12.1 7.8e-06 25.5 8.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGG10527.1 - 0.00013 21.7 10.1 0.00024 20.8 7.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 EGG10527.1 - 0.0031 17.2 3.4 0.0062 16.2 2.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein stn_TNFRSF12A PF12191.3 EGG10527.1 - 0.0035 17.3 0.2 0.0074 16.3 0.2 1.4 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Rootletin PF15035.1 EGG10527.1 - 0.005 16.8 67.3 0.011 15.6 5.3 6.3 3 2 3 6 6 6 3 Ciliary rootlet component, centrosome cohesion Laminin_I PF06008.9 EGG10527.1 - 0.0059 15.9 3.9 0.0059 15.9 2.7 5.6 3 1 2 5 5 4 1 Laminin Domain I GIDA_assoc_3 PF13932.1 EGG10527.1 - 0.039 13.9 3.8 7.5 6.7 0.3 3.7 1 1 1 2 2 2 0 GidA associated domain 3 Reo_sigmaC PF04582.7 EGG10527.1 - 0.091 11.9 41.6 0.1 11.7 1.3 4.9 2 2 3 5 5 5 0 Reovirus sigma C capsid protein zf-rbx1 PF12678.2 EGG10527.1 - 0.17 12.0 5.7 0.33 11.0 4.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-CHY PF05495.7 EGG10527.1 - 0.69 10.1 6.8 1.5 9.0 4.7 1.5 1 0 0 1 1 1 0 CHY zinc finger zf-C3HC4_4 PF15227.1 EGG10527.1 - 0.73 9.7 8.0 1.4 8.8 5.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Matrilin_ccoil PF10393.4 EGG10527.1 - 0.96 8.8 13.9 4.1 6.8 0.3 5.1 5 0 0 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin zf-RING_UBOX PF13445.1 EGG10527.1 - 1.3 8.7 8.1 4.4 7.1 5.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EGG10527.1 - 7.7 6.1 8.6 37 4.0 6.0 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain ANTH PF07651.11 EGG10529.1 - 1e-48 165.5 0.0 1.5e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EGG10529.1 - 0.00094 19.0 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 2 1 ENTH domain Baculo_PEP_C PF04513.7 EGG10530.1 - 0.0056 16.5 1.1 0.01 15.6 0.7 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ATE_C PF04377.10 EGG10531.1 - 2.5e-43 147.1 0.1 4.9e-43 146.2 0.1 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EGG10531.1 - 8.2e-22 76.8 1.2 1.4e-21 76.0 0.9 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus PEPcase PF00311.12 EGG10531.1 - 0.016 13.0 0.0 0.022 12.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase RabGAP-TBC PF00566.13 EGG10532.1 - 7e-05 22.3 0.0 0.00027 20.4 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SecE PF00584.15 EGG10534.1 - 6e-15 54.5 0.0 7.2e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex AHH PF14412.1 EGG10535.1 - 0.063 13.2 0.2 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF904 PF06005.7 EGG10535.1 - 0.12 12.6 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) OTU PF02338.14 EGG10537.1 - 0.0018 18.8 0.0 0.0036 17.8 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease 2OG-FeII_Oxy PF03171.15 EGG10541.1 - 1.9e-19 69.8 0.0 2.6e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Polyketide_cyc PF03364.15 EGG10542.1 - 1.5e-18 67.0 0.1 2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF3850 PF12961.2 EGG10542.1 - 0.057 13.4 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3850) KH_1 PF00013.24 EGG10543.1 - 9e-53 175.7 55.6 9e-11 41.2 0.7 13.0 12 0 0 12 12 12 10 KH domain KH_3 PF13014.1 EGG10543.1 - 2.8e-28 97.0 35.8 4.1e-05 23.1 0.0 11.7 13 0 0 13 13 13 8 KH domain KH_2 PF07650.12 EGG10543.1 - 2.3e-05 23.8 37.6 0.026 14.0 0.2 8.4 7 3 1 8 8 8 5 KH domain tRNA-synt_1c PF00749.16 EGG10545.1 - 6.1e-101 337.1 0.0 1.2e-100 336.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGG10545.1 - 2.5e-34 118.4 0.0 5e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 EGG10545.1 - 1.5e-23 83.1 0.6 2.7e-23 82.3 0.1 1.6 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 EGG10545.1 - 5.3e-10 39.8 0.4 1.4e-09 38.4 0.2 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 adh_short PF00106.20 EGG10548.1 - 1.3e-11 44.6 0.1 9.4e-08 32.1 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EGG10548.1 - 0.0074 15.9 0.1 0.046 13.3 0.0 1.9 2 0 0 2 2 2 1 KR domain WD40 PF00400.27 EGG10549.1 - 4.4e-65 213.4 31.7 1.9e-09 37.0 0.1 11.4 11 0 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 EGG10549.1 - 3.5e-29 101.2 0.8 6.1e-29 100.4 0.6 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EGG10549.1 - 1.2e-05 23.6 9.4 0.012 13.8 1.9 3.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EGG10549.1 - 0.0024 17.6 1.5 0.074 12.8 0.0 4.3 6 1 1 7 7 7 1 Ciliary BBSome complex subunit 2, middle region Glyco_transf_20 PF00982.16 EGG10551.1 - 9.2e-144 479.4 0.0 1.1e-143 479.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EGG10551.1 - 3.9e-71 238.6 0.0 5.6e-71 238.1 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_trans_1_4 PF13692.1 EGG10551.1 - 0.0019 18.3 0.0 0.005 16.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EGG10551.1 - 0.0081 15.5 0.0 1 8.7 0.0 2.8 2 1 0 2 2 2 1 Glycosyl transferases group 1 DUF202 PF02656.10 EGG10552.1 - 1.3e-13 50.9 2.4 1.3e-13 50.9 1.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Fer2_BFD PF04324.10 EGG10553.1 - 0.41 10.7 4.0 0.54 10.3 2.7 1.4 1 1 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Condensin2nSMC PF12422.3 EGG10554.1 - 0.21 11.3 1.3 0.58 9.8 0.3 1.9 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit zf-MYND PF01753.13 EGG10555.1 - 5.1e-09 35.8 15.1 8.8e-09 35.1 10.5 1.4 1 0 0 1 1 1 1 MYND finger TPR_12 PF13424.1 EGG10555.1 - 2.2e-05 24.2 0.1 0.021 14.7 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGG10555.1 - 0.00011 21.8 0.0 0.098 12.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGG10555.1 - 0.00031 20.3 0.0 0.00092 18.8 0.0 1.8 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EGG10555.1 - 0.00053 19.4 0.1 0.88 9.2 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGG10555.1 - 0.001 18.7 0.1 1.2 9.0 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGG10555.1 - 0.0016 18.4 0.0 1.4 9.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGG10555.1 - 0.002 17.9 0.0 0.034 14.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGG10555.1 - 0.0028 18.1 0.0 0.018 15.6 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGG10555.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EGG10555.1 - 0.032 13.7 0.7 0.075 12.5 0.1 1.8 2 0 0 2 2 2 0 Foie gras liver health family 1 TPR_16 PF13432.1 EGG10555.1 - 0.041 14.5 0.0 0.08 13.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RPN7 PF10602.4 EGG10555.1 - 0.11 11.8 0.3 1 8.6 0.2 2.1 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_7 PF13176.1 EGG10555.1 - 0.12 12.1 0.0 9.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF964 PF06133.6 EGG10555.1 - 0.15 12.1 1.3 7 6.7 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF964) zf-C2H2_3 PF13878.1 EGG10555.1 - 0.21 11.2 4.8 0.41 10.2 3.4 1.5 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Arf PF00025.16 EGG10557.1 - 5.4e-76 253.7 0.0 6e-76 253.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGG10557.1 - 3.7e-13 49.1 0.0 4.3e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EGG10557.1 - 2.9e-12 46.1 0.0 3.7e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGG10557.1 - 1.4e-11 43.7 0.8 1.8e-07 30.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGG10557.1 - 3.3e-10 39.4 0.0 4e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGG10557.1 - 8.8e-08 32.6 0.0 1.2e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGG10557.1 - 9.7e-05 22.3 0.0 0.00021 21.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EGG10557.1 - 0.0017 17.4 0.1 0.0028 16.7 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EGG10557.1 - 0.011 15.1 0.0 0.071 12.5 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain L27 PF02828.11 EGG10557.1 - 0.027 14.1 0.4 0.094 12.4 0.1 1.9 2 0 0 2 2 2 0 L27 domain HAMP PF00672.20 EGG10558.1 - 1.3e-52 175.8 33.6 1.8e-09 37.6 0.2 10.4 7 3 3 10 10 10 8 HAMP domain HATPase_c PF02518.21 EGG10558.1 - 5e-28 97.0 1.2 1.5e-27 95.5 0.8 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGG10558.1 - 1.7e-20 73.0 0.1 5.3e-20 71.5 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EGG10558.1 - 1.6e-15 56.8 0.5 1.6e-15 56.8 0.4 4.0 5 0 0 5 5 5 1 His Kinase A (phospho-acceptor) domain DUF1843 PF08898.5 EGG10558.1 - 0.66 10.0 10.2 53 3.9 0.1 6.3 7 1 0 7 7 7 0 Domain of unknown function (DUF1843) Tape_meas_lam_C PF09718.5 EGG10558.1 - 6.5 6.7 12.0 4.7 7.1 1.2 4.6 4 0 0 4 4 4 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) WD40 PF00400.27 EGG10559.1 - 1.5e-74 243.3 28.9 1.2e-14 53.5 0.2 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGG10559.1 - 7.3e-12 44.1 10.6 0.015 13.4 0.0 5.9 1 1 3 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGG10559.1 - 1.6e-06 27.1 2.7 0.17 10.5 0.0 4.3 1 1 2 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 EGG10559.1 - 0.038 12.3 0.1 1 7.5 0.0 2.4 2 1 1 3 3 3 0 Cytochrome D1 heme domain bZIP_2 PF07716.10 EGG10559.1 - 0.17 11.6 0.5 0.31 10.9 0.3 1.3 1 0 0 1 1 1 0 Basic region leucine zipper dsrm PF00035.20 EGG10563.1 - 0.056 14.0 1.9 0.51 10.9 0.3 2.3 1 1 1 2 2 2 0 Double-stranded RNA binding motif DUF572 PF04502.8 EGG10568.1 - 0.0078 15.4 4.5 0.012 14.9 3.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) THRAP3_BCLAF1 PF15440.1 EGG10568.1 - 0.026 13.1 6.0 0.036 12.7 4.2 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF1117 PF06547.7 EGG10568.1 - 0.95 9.5 3.8 1.2 9.2 1.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1117) RAP1 PF07218.6 EGG10569.1 - 0.89 7.5 2.9 1.2 7.1 2.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Med3 PF11593.3 EGG10569.1 - 9.7 5.3 11.0 13 4.8 7.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LRR_4 PF12799.2 EGG10570.1 - 0.023 14.3 0.3 5.3 6.7 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG10570.1 - 0.27 11.0 3.6 1.1 9.0 0.0 2.8 2 1 1 3 3 3 0 Leucine rich repeat FNIP PF05725.7 EGG10570.1 - 0.51 10.3 4.0 9.6 6.2 0.1 3.6 3 0 0 3 3 3 0 FNIP Repeat KAR PF15222.1 EGG10573.1 - 0.035 14.1 3.3 0.082 12.9 2.3 1.7 1 1 0 1 1 1 0 Kidney androgen-regulated Ribosomal_L13 PF00572.13 EGG10577.1 - 6.5e-38 129.6 0.2 7.7e-38 129.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_L13 PF00572.13 EGG10578.1 - 6.5e-38 129.6 0.2 7.7e-38 129.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 YjbE PF11106.3 EGG10580.1 - 0.19 11.7 2.0 16 5.5 0.3 2.3 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE DUF4175 PF13779.1 EGG10580.1 - 3.1 5.3 19.7 3.8 5.0 13.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Daxx PF03344.10 EGG10580.1 - 4.7 5.5 16.9 5.2 5.4 11.7 1.0 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EGG10580.1 - 8.4 4.2 10.1 8.6 4.2 7.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Thi4 PF01946.12 EGG10583.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Fungal_trans PF04082.13 EGG10584.1 - 1.5e-15 56.8 2.5 2e-15 56.3 0.3 2.0 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGG10584.1 - 2.1e-07 30.7 6.5 3.5e-07 30.0 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1765 PF08578.5 EGG10586.1 - 8.3e-29 100.1 0.3 1.6e-28 99.2 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) An_peroxidase PF03098.10 EGG10587.1 - 4.2e-62 210.2 0.0 5.8e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase F-box-like PF12937.2 EGG10589.1 - 0.0056 16.3 0.1 0.016 14.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGG10589.1 - 0.017 14.7 0.8 0.06 13.0 0.1 2.3 2 0 0 2 2 2 0 F-box domain zf-C2H2 PF00096.21 EGG10590.1 - 8.1e-11 41.6 9.2 1.6e-05 24.9 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG10590.1 - 1.3e-06 28.2 8.6 0.00033 20.7 1.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGG10590.1 - 2.6e-05 23.9 6.4 0.0026 17.6 0.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGG10590.1 - 0.00022 21.2 1.2 0.24 11.5 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGG10590.1 - 0.0045 17.1 4.3 0.72 10.1 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EGG10590.1 - 0.02 14.5 8.8 0.17 11.6 0.6 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 EGG10590.1 - 0.043 14.1 10.5 0.083 13.2 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-BED PF02892.10 EGG10590.1 - 0.41 10.4 5.6 7.3 6.4 0.3 2.6 1 1 1 2 2 2 0 BED zinc finger FYVE PF01363.16 EGG10590.1 - 3.1 7.7 6.9 15 5.5 4.8 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-ribbon_3 PF13248.1 EGG10590.1 - 3.4 6.9 6.1 0.19 10.9 0.3 1.9 2 0 0 2 2 2 0 zinc-ribbon domain OTCace PF00185.19 EGG10591.1 - 8.4e-43 145.9 0.0 1.4e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EGG10591.1 - 7.3e-40 135.9 0.1 1.4e-39 135.0 0.1 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain zf-RING_2 PF13639.1 EGG10592.1 - 3.9e-06 26.5 7.1 6e-06 25.9 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGG10592.1 - 0.00045 19.8 7.3 0.00073 19.1 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGG10592.1 - 0.00067 19.1 8.8 0.0012 18.4 6.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 EGG10592.1 - 0.0024 17.5 7.2 0.0038 16.8 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG10592.1 - 0.014 15.3 7.8 0.023 14.7 5.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 EGG10592.1 - 0.068 12.9 5.3 0.12 12.0 3.7 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) GAF_2 PF13185.1 EGG10592.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 GAF domain zf-RING_5 PF14634.1 EGG10592.1 - 0.63 9.8 7.8 1.2 8.9 5.4 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 EGG10592.1 - 0.88 9.4 5.1 2.7 7.9 3.5 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EGG10593.1 - 1.9e-06 27.5 7.8 2.7e-06 27.0 5.4 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 EGG10593.1 - 1.4e-05 24.5 6.1 2.3e-05 23.8 4.2 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EGG10593.1 - 3.2e-05 23.4 5.9 5e-05 22.8 4.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG10593.1 - 0.00013 21.5 7.2 0.0002 20.9 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG10593.1 - 0.00024 21.0 7.7 0.00042 20.2 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG10593.1 - 0.0015 18.2 7.1 0.0021 17.7 4.9 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGG10593.1 - 2.7 7.9 6.6 7.1 6.5 4.6 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Sigma70_ner PF04546.8 EGG10595.1 - 0.0013 18.4 1.2 1.4 8.5 0.2 3.2 3 0 0 3 3 3 2 Sigma-70, non-essential region OTCace PF00185.19 EGG10598.1 - 1.8e-10 40.9 0.0 2e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ArfGap PF01412.13 EGG10600.1 - 3.7e-42 142.7 0.4 5e-42 142.3 0.2 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf OSCP PF00213.13 EGG10602.1 - 1.4e-39 135.7 1.7 1.6e-39 135.4 1.2 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit LXG PF04740.7 EGG10602.1 - 0.016 14.9 0.6 0.15 11.8 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily FANCF PF11107.3 EGG10602.1 - 0.047 12.9 0.3 0.057 12.6 0.2 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) Alpha_kinase PF02816.13 EGG10605.1 - 0.0018 17.9 1.4 0.0044 16.7 1.0 1.7 1 1 0 1 1 1 1 Alpha-kinase family HMG_box PF00505.14 EGG10610.1 - 1.6e-18 66.7 7.1 4.1e-10 39.7 1.2 3.2 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EGG10610.1 - 4.1e-14 52.6 3.0 8.9e-08 32.3 0.1 2.7 2 0 0 2 2 2 2 HMG-box domain DUF3340 PF11818.3 EGG10610.1 - 0.042 13.8 5.5 0.27 11.1 0.3 2.3 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) HSCB_C PF07743.8 EGG10610.1 - 0.055 13.9 4.7 3.2 8.2 0.3 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Enkurin PF13864.1 EGG10610.1 - 0.095 12.9 5.4 0.14 12.3 0.2 2.4 2 0 0 2 2 2 0 Calmodulin-binding Metal_resist PF13801.1 EGG10610.1 - 0.51 10.3 3.9 0.14 12.1 0.3 1.8 2 0 0 2 2 2 0 Heavy-metal resistance OmpH PF03938.9 EGG10610.1 - 1.8 8.4 7.7 1.5 8.7 0.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4355 PF14265.1 EGG10610.1 - 5.5 6.9 11.3 2.9 7.8 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) UBN2 PF14223.1 EGG10613.1 - 2.9e-06 27.0 0.2 1.5e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG10613.1 - 0.00026 20.5 1.3 0.00079 18.9 0.0 2.5 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type PIN_4 PF13638.1 EGG10614.1 - 6.3e-22 78.0 2.4 3.3e-21 75.7 1.7 2.3 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.4 EGG10614.1 - 3.7e-07 29.6 3.6 3.2e-06 26.5 0.1 3.3 3 1 0 3 3 3 1 Est1 DNA/RNA binding domain Fcf1 PF04900.7 EGG10615.1 - 1.8e-18 66.5 0.1 1.8e-18 66.5 0.1 2.7 2 2 1 3 3 3 1 Fcf1 DUF645 PF04875.7 EGG10617.1 - 0.3 10.8 2.4 0.32 10.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function, DUF645 zf-C3HC4_2 PF13923.1 EGG10618.1 - 2.3e-06 27.5 6.9 7.4e-06 25.8 4.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGG10618.1 - 0.00035 20.3 6.1 0.00035 20.3 4.2 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGG10618.1 - 0.00043 19.8 6.4 0.0014 18.2 4.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG10618.1 - 0.001 18.7 2.6 0.0028 17.2 1.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 EGG10618.1 - 0.019 14.9 0.9 0.1 12.6 0.3 2.5 1 1 1 2 2 2 0 U-box domain zf-RING_6 PF14835.1 EGG10618.1 - 0.022 14.5 2.5 0.043 13.6 1.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 EGG10618.1 - 0.036 13.5 4.6 0.071 12.6 2.4 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EGG10618.1 - 0.21 11.4 8.5 0.74 9.7 5.9 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 EGG10618.1 - 0.37 10.2 9.9 9.3 5.8 6.8 3.0 1 1 1 2 2 2 0 P-11 zinc finger AATF-Che1 PF13339.1 EGG10618.1 - 1.2 9.3 5.9 1.6 8.8 0.1 2.9 2 1 0 3 3 3 0 Apoptosis antagonizing transcription factor zf-RING_5 PF14634.1 EGG10618.1 - 1.5 8.5 10.1 0.062 13.0 2.5 2.1 2 0 0 2 2 2 0 zinc-RING finger domain SIR2 PF02146.12 EGG10619.1 - 1.2e-25 90.3 0.0 1.5e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Lectin_leg-like PF03388.8 EGG10620.1 - 3.8e-41 140.6 0.0 5.6e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EGG10620.1 - 0.048 13.0 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 Legume lectin domain NAD_binding_8 PF13450.1 EGG10621.1 - 3.1e-12 46.3 0.0 6.4e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGG10621.1 - 0.00023 20.1 0.1 0.00032 19.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGG10621.1 - 0.0013 18.8 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGG10621.1 - 0.0033 16.5 0.0 0.0039 16.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EGG10621.1 - 0.007 16.1 0.0 0.013 15.3 0.0 1.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGG10621.1 - 0.036 13.9 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGG10621.1 - 0.074 11.4 0.1 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EGG10621.1 - 0.11 12.8 0.2 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Antimicrobial_7 PF08102.6 EGG10622.1 - 0.2 11.7 0.6 0.82 9.7 0.0 2.0 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3464 PF11947.3 EGG10624.1 - 0.1 12.0 4.3 0.19 11.1 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Kinesin-related PF06548.6 EGG10624.1 - 0.34 9.3 5.7 0.44 9.0 4.0 1.0 1 0 0 1 1 1 0 Kinesin-related Bax1-I PF01027.15 EGG10627.1 - 2.7e-43 147.9 29.3 3.3e-43 147.7 20.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4005 PF13178.1 EGG10631.1 - 0.12 12.6 0.7 0.18 12.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4005) Glyco_transf_25 PF01755.12 EGG10632.1 - 1e-10 41.6 0.9 0.00022 20.9 0.2 3.2 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Ehbp PF10622.4 EGG10632.1 - 0.0027 17.6 0.6 0.011 15.6 0.1 2.2 2 0 0 2 2 2 1 Energy-converting hydrogenase B subunit P (EhbP) Nse4_C PF08743.5 EGG10633.1 - 2.6e-23 81.8 0.3 2.6e-23 81.8 0.2 2.2 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EGG10633.1 - 6.9e-10 38.6 2.7 6.9e-10 38.6 1.9 2.1 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE Osteopontin PF00865.13 EGG10633.1 - 2.9 7.0 11.5 0.16 11.1 1.3 2.4 2 0 0 2 2 2 0 Osteopontin Diphthamide_syn PF01866.12 EGG10634.1 - 5.6e-50 170.3 0.0 9.2e-49 166.3 0.0 2.0 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Nanovirus_coat PF04660.7 EGG10634.1 - 0.056 13.1 0.2 0.72 9.5 0.1 2.1 2 0 0 2 2 2 0 Nanovirus coat protein RhoGEF PF00621.15 EGG10635.1 - 1.4e-08 34.8 0.0 1.3e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain PH PF00169.24 EGG10635.1 - 0.0053 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PI3_PI4_kinase PF00454.22 EGG10636.1 - 1.1e-33 116.7 0.0 1.7e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase REV PF00424.13 EGG10638.1 - 1.5 8.7 8.6 0.18 11.6 1.1 2.9 4 0 0 4 4 4 0 REV protein (anti-repression trans-activator protein) E1_dh PF00676.15 EGG10639.1 - 3.4e-09 35.8 0.0 3.9e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component MOZ_SAS PF01853.13 EGG10640.1 - 2.4e-84 281.2 1.1 3.6e-84 280.7 0.7 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EGG10640.1 - 3.1e-10 39.5 0.0 8.3e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HTH_6 PF01418.12 EGG10640.1 - 0.022 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Acetyltransf_1 PF00583.19 EGG10640.1 - 0.036 14.1 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-H2C2_5 PF13909.1 EGG10640.1 - 0.37 11.1 3.0 1.4 9.2 2.0 2.0 1 0 0 1 1 1 0 C2H2-type zinc-finger domain PPP4R2 PF09184.6 EGG10640.1 - 2.8 7.3 14.8 4.6 6.7 10.3 1.2 1 0 0 1 1 1 0 PPP4R2 EF-hand_1 PF00036.27 EGG10642.1 - 1.1e-26 90.0 8.2 6.8e-09 34.4 0.0 5.0 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 EGG10642.1 - 1.2e-24 86.2 3.4 1.7e-16 60.0 0.2 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGG10642.1 - 4.7e-23 78.9 3.0 7.6e-06 25.3 0.2 5.2 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 EGG10642.1 - 1.2e-15 56.0 8.6 9.9e-05 21.5 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EGG10642.1 - 1.4e-14 53.4 8.3 3.3e-05 23.4 1.0 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EGG10642.1 - 9.7e-08 31.6 2.2 0.0077 15.9 0.0 3.9 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGG10642.1 - 4.2e-06 26.7 0.9 0.0063 16.5 0.1 3.1 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EGG10642.1 - 0.0017 18.1 0.8 0.051 13.4 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain EF-hand_2 PF09068.6 EGG10642.1 - 0.0069 16.4 0.2 1 9.4 0.0 2.8 3 1 0 3 3 3 1 EF hand S10_plectin PF03501.10 EGG10642.1 - 0.047 13.5 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_10 PF14788.1 EGG10642.1 - 0.052 13.2 1.9 36 4.1 0.0 4.1 5 0 0 5 5 5 0 EF hand PMBR PF09373.5 EGG10642.1 - 0.055 13.4 0.1 17 5.5 0.0 3.3 4 0 0 4 4 4 0 Pseudomurein-binding repeat Mad3_BUB1_II PF08171.6 EGG10642.1 - 0.089 12.6 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 p25-alpha PF05517.7 EGG10642.1 - 0.29 11.3 1.8 7.4 6.8 0.0 2.4 2 1 0 2 2 2 0 p25-alpha F-box-like PF12937.2 EGG10643.1 - 0.025 14.3 0.3 0.025 14.3 0.2 2.1 2 0 0 2 2 2 0 F-box-like FTA4 PF13093.1 EGG10643.1 - 0.032 13.6 0.8 0.051 13.0 0.5 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ADP_PFK_GK PF04587.10 EGG10643.1 - 0.17 10.0 0.0 0.29 9.3 0.0 1.4 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region DHHA2 PF02833.9 EGG10644.1 - 2.9e-16 59.8 0.1 6.5e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EGG10644.1 - 1.8e-11 43.9 0.0 3.5e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 DHH family HNF-1A_C PF04813.7 EGG10644.1 - 0.037 14.3 0.8 0.65 10.2 0.0 3.3 4 0 0 4 4 4 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus DUF4611 PF15387.1 EGG10644.1 - 0.065 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) 7tm_6 PF02949.15 EGG10645.1 - 0.065 12.0 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 7tm Odorant receptor zf-DBF PF07535.7 EGG10646.1 - 1.8e-20 72.3 1.7 3.7e-20 71.3 1.2 1.5 1 0 0 1 1 1 1 DBF zinc finger Dfp1_Him1_M PF08630.5 EGG10646.1 - 1.8e-19 69.7 0.1 9e-19 67.4 0.0 2.3 1 0 0 1 1 1 1 Dfp1/Him1, central region BRCT PF00533.21 EGG10646.1 - 0.0021 18.1 0.0 0.0097 16.0 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3716 PF12511.3 EGG10646.1 - 0.08 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) PTCB-BRCT PF12738.2 EGG10646.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain DUF3439 PF11921.3 EGG10646.1 - 0.56 9.9 5.3 1.5 8.5 3.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PLA2_B PF01735.13 EGG10647.1 - 8.4e-101 337.5 0.1 9.5e-92 307.6 0.0 2.1 1 1 1 2 2 2 2 Lysophospholipase catalytic domain Hexapep PF00132.19 EGG10648.1 - 2.3e-12 45.8 18.8 3.9e-08 32.4 2.3 4.9 3 2 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGG10648.1 - 2.1e-09 36.7 12.5 0.00038 19.9 1.8 3.7 3 1 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EGG10648.1 - 0.0039 15.8 0.1 0.0057 15.2 0.1 1.2 1 0 0 1 1 1 1 L-fucokinase Phasin PF05597.6 EGG10650.1 - 0.0017 18.1 1.5 0.56 9.9 0.6 3.6 3 1 0 3 3 3 1 Poly(hydroxyalcanoate) granule associated protein (phasin) NPV_P10 PF05531.7 EGG10650.1 - 0.0068 16.6 7.0 0.068 13.4 1.7 3.1 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 EGG10650.1 - 0.016 14.9 1.1 0.095 12.4 0.3 2.2 2 0 0 2 2 2 0 Laminin Domain II Nup54 PF13874.1 EGG10650.1 - 0.025 14.2 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 MCPsignal PF00015.16 EGG10650.1 - 0.31 10.5 2.9 1.7 8.1 0.1 2.4 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LPP PF04728.8 EGG10650.1 - 0.89 9.4 7.5 7.4 6.4 0.4 2.8 2 1 1 3 3 3 0 Lipoprotein leucine-zipper BAG PF02179.11 EGG10652.1 - 2.2e-10 40.5 0.8 4.2e-10 39.6 0.6 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EGG10652.1 - 0.00047 19.4 0.0 0.0055 16.0 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.1 EGG10652.1 - 0.0012 19.1 1.5 0.038 14.2 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin-like domain Pkinase PF00069.20 EGG10653.1 - 1.2e-54 185.2 0.0 1.4e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG10653.1 - 6.5e-40 136.8 0.0 8.5e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG10653.1 - 6e-06 25.4 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pectinesterase PF01095.14 EGG10654.1 - 9.8e-32 109.7 0.0 1.2e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Pectinesterase Na_Ca_ex PF01699.19 EGG10655.1 - 2.2 7.8 9.5 0.19 11.3 2.5 2.3 2 2 1 3 3 3 0 Sodium/calcium exchanger protein Complex1_LYR_2 PF13233.1 EGG10660.1 - 3.2e-06 27.5 0.1 7.6e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Lectin_leg-like PF03388.8 EGG10662.1 - 1.1e-61 207.9 0.1 1.5e-61 207.4 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EGG10662.1 - 1.2e-05 24.7 0.2 2.4e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 Legume lectin domain DUF2518 PF10726.4 EGG10662.1 - 0.17 11.3 1.6 0.35 10.3 1.1 1.4 1 0 0 1 1 1 0 Protein of function (DUF2518) AhpC-TSA_2 PF13911.1 EGG10663.1 - 2.8e-12 46.5 0.0 6.6e-12 45.3 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGG10663.1 - 1.1e-06 28.3 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family CRC_subunit PF08624.5 EGG10664.1 - 4e-35 120.7 0.0 8.1e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Phage_Gp23 PF10669.4 EGG10664.1 - 0.97 9.5 7.5 3.3 7.8 5.2 1.8 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Ribosomal_L39 PF00832.15 EGG10665.1 - 1.4e-19 69.2 6.6 1.7e-19 68.9 4.6 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein COMPASS-Shg1 PF05205.7 EGG10667.1 - 1.3e-07 31.8 1.0 3.3e-07 30.5 0.7 1.7 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Vps26 PF03643.10 EGG10668.1 - 1.3e-127 424.3 4.1 1.4e-127 424.1 2.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EGG10668.1 - 0.041 13.7 3.8 4.8 6.9 0.0 3.5 3 1 0 4 4 4 0 Arrestin (or S-antigen), N-terminal domain PPP1R35_C PF15503.1 EGG10670.1 - 0.027 14.0 0.1 0.027 14.0 0.1 2.5 3 0 0 3 3 3 0 Protein phosphatase 1 regulatory subunit 35 C-terminus DPBB_1 PF03330.13 EGG10672.1 - 6.7e-06 26.0 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pterin_bind PF00809.17 EGG10677.1 - 2e-29 102.5 0.1 3.2e-29 101.8 0.1 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EGG10677.1 - 1.3e-24 86.3 0.0 2.4e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) adh_short PF00106.20 EGG10678.1 - 1.2e-11 44.7 0.5 1.5e-11 44.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG10678.1 - 0.00075 19.1 0.3 0.001 18.7 0.2 1.1 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EGG10678.1 - 0.0083 15.9 1.0 0.012 15.4 0.7 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DUF1018 PF06252.7 EGG10678.1 - 0.078 13.4 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) ADH_zinc_N PF00107.21 EGG10678.1 - 0.092 12.3 0.7 0.65 9.5 0.2 2.0 1 1 1 2 2 2 0 Zinc-binding dehydrogenase STAT1_TAZ2bind PF12162.3 EGG10679.1 - 0.068 12.6 0.1 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain Arginase PF00491.16 EGG10681.1 - 0.084 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Arginase family Pkinase PF00069.20 EGG10682.1 - 9.1e-05 21.7 0.2 0.0001 21.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Glyco_hydro_85 PF03644.8 EGG10685.1 - 0.019 14.0 0.1 0.025 13.7 0.1 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 85 PolyA_pol PF01743.15 EGG10689.1 - 1.4e-07 31.8 0.2 2.1e-07 31.2 0.2 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain DUF2827 PF10933.3 EGG10690.1 - 0.012 14.0 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) PI3K_1B_p101 PF10486.4 EGG10691.1 - 3.4 5.1 20.9 0.62 7.5 11.9 1.5 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit W2 PF02020.13 EGG10695.1 - 5.9e-17 61.4 0.1 2e-16 59.7 0.1 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon RasGEF PF00617.14 EGG10696.1 - 5.5e-65 218.6 0.0 1.1e-64 217.6 0.0 1.5 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EGG10696.1 - 9.2e-26 89.9 0.0 1.7e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Alpha_kinase PF02816.13 EGG10697.1 - 6.7e-21 74.8 1.5 8.5e-21 74.4 0.6 1.6 2 0 0 2 2 2 1 Alpha-kinase family Peptidase_M61 PF05299.7 EGG10697.1 - 0.071 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 M61 glycyl aminopeptidase HAD_2 PF13419.1 EGG10698.1 - 2.1e-17 63.9 0.0 3.8e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGG10698.1 - 1.6e-11 45.0 0.0 1.1e-10 42.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGG10698.1 - 1.6e-08 34.1 0.0 3.5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EGG10698.1 - 0.011 15.8 0.0 0.03 14.4 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Corona_nucleoca PF00937.13 EGG10698.1 - 0.54 9.1 5.9 0.75 8.6 4.1 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein HAD_2 PF13419.1 EGG10699.1 - 1.5e-17 64.3 0.1 3.3e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGG10699.1 - 1.4e-11 45.2 0.1 7.9e-11 42.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGG10699.1 - 8.7e-09 34.9 0.0 1.9e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EGG10699.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PP2C_2 PF13672.1 EGG10699.1 - 0.035 13.4 0.1 0.085 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 2C Corona_nucleoca PF00937.13 EGG10699.1 - 0.035 13.0 3.5 0.05 12.5 2.4 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CPSase_sm_chain PF00988.17 EGG10701.1 - 2.5e-43 146.7 0.0 4.3e-43 145.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EGG10701.1 - 9.4e-37 126.3 0.0 1.4e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGG10701.1 - 1e-07 31.6 0.3 3.2e-06 26.7 0.2 2.8 1 1 0 1 1 1 1 Peptidase C26 SNF2_N PF00176.18 EGG10702.1 - 2e-66 223.8 2.0 3.1e-66 223.1 1.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 EGG10702.1 - 1.1e-19 70.5 1.3 1.1e-19 70.5 0.9 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.19 EGG10702.1 - 7.9e-16 57.4 7.6 1.1e-11 44.2 0.1 3.7 2 1 1 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EGG10702.1 - 7.9e-15 54.4 0.0 2.1e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGG10702.1 - 2.4e-06 27.1 0.0 4.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TBP PF00352.16 EGG10702.1 - 0.03 13.6 0.0 0.092 12.1 0.0 1.8 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) DNA_circ_N PF07157.7 EGG10702.1 - 0.088 12.9 0.4 31 4.7 0.0 3.4 3 0 0 3 3 3 0 DNA circularisation protein N-terminus GPI-anchored PF10342.4 EGG10703.1 - 4.1e-08 33.6 0.8 4.1e-08 33.6 0.6 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EGG10703.1 - 0.084 12.3 0.1 0.094 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EGG10704.1 - 1.1e-09 38.5 1.0 1.1e-09 38.5 0.7 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family V-ATPase_H_N PF03224.9 EGG10705.1 - 1.6e-67 227.8 2.6 1.6e-67 227.8 1.8 1.9 2 1 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EGG10705.1 - 2.3e-42 143.6 0.6 1.8e-39 134.3 0.0 3.1 3 0 0 3 3 3 2 V-ATPase subunit H Arm_2 PF04826.8 EGG10705.1 - 0.0003 19.9 0.1 0.0003 19.9 0.1 2.4 3 0 0 3 3 3 1 Armadillo-like HEAT_2 PF13646.1 EGG10705.1 - 0.0027 17.9 0.4 0.15 12.3 0.0 3.2 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 EGG10705.1 - 0.046 13.8 0.0 1.5 9.0 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat HA2 PF04408.18 EGG10707.1 - 6.9e-19 67.7 0.0 2.5e-18 65.9 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGG10707.1 - 2.2e-12 46.6 0.5 1.6e-11 43.8 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGG10707.1 - 5e-10 39.1 0.6 1.2e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EGG10707.1 - 1.6e-07 31.1 0.0 6.1e-07 29.2 0.0 2.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EGG10707.1 - 4.2e-07 30.1 0.1 1.8e-06 28.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGG10707.1 - 0.0018 18.5 1.2 0.0056 16.9 0.0 2.5 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 EGG10707.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain LEP503 PF15221.1 EGG10707.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 PLA2_B PF01735.13 EGG10708.1 - 2.2e-90 303.1 4.7 5.1e-74 249.2 0.0 3.0 2 1 0 2 2 2 2 Lysophospholipase catalytic domain ZZ PF00569.12 EGG10711.1 - 1.3e-14 53.4 29.3 1.3e-09 37.4 2.5 3.5 4 0 0 4 4 4 2 Zinc finger, ZZ type zf-C3HC4_2 PF13923.1 EGG10711.1 - 5.2e-09 35.9 9.4 5.2e-09 35.9 6.5 3.8 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGG10711.1 - 3.4e-07 29.9 8.0 3.4e-07 29.9 5.5 3.5 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGG10711.1 - 3.8e-07 29.6 8.2 3.8e-07 29.6 5.7 4.6 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG10711.1 - 3.7e-06 26.5 4.7 3.7e-06 26.5 3.2 4.0 3 2 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGG10711.1 - 4.4e-06 26.2 3.0 4.4e-06 26.2 2.1 4.3 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGG10711.1 - 3e-05 23.6 6.7 0.00018 21.1 4.6 2.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGG10711.1 - 0.0007 19.6 8.1 0.0007 19.6 5.6 3.4 2 2 1 3 3 3 1 RING-H2 zinc finger U-box PF04564.10 EGG10711.1 - 0.0011 18.8 0.1 0.0033 17.3 0.1 1.8 1 0 0 1 1 1 1 U-box domain bZIP_1 PF00170.16 EGG10711.1 - 0.0013 18.6 2.6 0.0025 17.7 1.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor zf-RING_6 PF14835.1 EGG10711.1 - 0.0016 18.1 2.8 0.0016 18.1 1.9 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 EGG10711.1 - 0.0053 16.2 4.2 0.0053 16.2 2.9 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EGG10711.1 - 0.029 14.2 7.8 0.029 14.2 5.4 3.4 3 2 0 3 3 1 0 zinc finger of C3HC4-type, RING Fib_alpha PF08702.5 EGG10711.1 - 0.041 13.9 2.7 0.067 13.3 1.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Med21 PF11221.3 EGG10711.1 - 0.1 12.5 1.1 0.26 11.2 0.7 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex RTBV_P46 PF06216.6 EGG10711.1 - 0.13 11.0 1.6 0.19 10.5 1.1 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein IncA PF04156.9 EGG10711.1 - 0.21 11.1 4.7 0.31 10.6 3.3 1.2 1 0 0 1 1 1 0 IncA protein GldM_N PF12081.3 EGG10711.1 - 0.24 10.8 4.9 0.35 10.3 3.4 1.1 1 0 0 1 1 1 0 GldM N-terminal domain Glyco_hydro_65m PF03632.10 EGG10711.1 - 0.4 9.3 1.6 0.56 8.8 1.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain zf-RING_2 PF13639.1 EGG10713.1 - 1.3e-05 24.9 4.6 2.7e-05 23.9 3.2 1.5 1 0 0 1 1 1 1 Ring finger domain PWI PF01480.12 EGG10713.1 - 0.028 14.5 0.5 0.2 11.7 0.0 2.6 3 0 0 3 3 3 0 PWI domain BSD PF03909.12 EGG10713.1 - 0.066 12.9 0.3 0.28 10.9 0.2 2.1 1 0 0 1 1 1 0 BSD domain zf-C3HC4_2 PF13923.1 EGG10713.1 - 1.1 9.3 5.5 0.47 10.5 1.9 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DIOX_N PF14226.1 EGG10714.1 - 5.4e-26 91.4 0.0 8.8e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGG10714.1 - 1.5e-15 57.3 0.0 3.3e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tubulin PF00091.20 EGG10715.1 - 1.2e-55 188.6 0.0 1.8e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGG10715.1 - 4.8e-40 136.5 0.0 7.4e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EGG10715.1 - 0.00019 21.4 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EGG10715.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Myb_Cef PF11831.3 EGG10718.1 - 5.2e-61 205.8 0.0 5.2e-61 205.8 0.0 4.2 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EGG10718.1 - 1.7e-22 79.2 5.6 4.1e-11 42.7 0.4 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGG10718.1 - 5.7e-20 71.1 9.5 1.8e-13 50.3 2.8 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain PPR_2 PF13041.1 EGG10719.1 - 0.00014 21.7 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 PPR repeat family Borrelia_orfX PF04160.7 EGG10720.1 - 2.4 7.9 7.6 0.17 11.6 0.5 2.4 3 0 0 3 3 3 0 Orf-X protein Nro1 PF12753.2 EGG10722.1 - 1.9e-05 23.8 0.8 3.4e-05 22.9 0.5 1.4 1 1 0 1 1 1 1 Nuclear pore complex subunit Nro1 zf-CCCH PF00642.19 EGG10726.1 - 3.8e-13 48.7 12.4 7.7e-07 28.6 0.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EGG10726.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 EGG10726.1 - 0.047 13.6 2.5 1.1 9.2 0.5 2.4 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) DUF2083 PF09856.4 EGG10728.1 - 0.15 11.7 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) Baculo_PEP_C PF04513.7 EGG10729.1 - 0.00015 21.5 0.9 0.00073 19.3 0.1 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.7 EGG10729.1 - 0.00076 19.0 0.2 0.3 10.6 0.1 2.4 2 0 0 2 2 2 2 Heat shock factor binding protein 1 Laminin_II PF06009.7 EGG10729.1 - 0.0029 17.3 1.1 0.005 16.5 0.2 1.9 2 0 0 2 2 2 1 Laminin Domain II Syntaxin_2 PF14523.1 EGG10729.1 - 0.0083 16.1 1.1 0.0083 16.1 0.7 2.2 2 1 0 2 2 2 1 Syntaxin-like protein NPV_P10 PF05531.7 EGG10729.1 - 0.0086 16.3 1.7 0.024 14.8 0.7 2.2 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein GP41 PF00517.12 EGG10729.1 - 0.013 15.0 0.1 1.8 8.1 0.4 2.6 2 0 0 2 2 2 0 Retroviral envelope protein DUF1664 PF07889.7 EGG10729.1 - 0.041 13.6 1.1 0.12 12.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 EGG10729.1 - 0.078 12.8 2.5 0.1 12.4 0.8 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.13 EGG10729.1 - 0.08 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Sipho_Gp157 PF05565.6 EGG10729.1 - 0.086 12.4 0.1 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Siphovirus Gp157 MCPsignal PF00015.16 EGG10729.1 - 0.097 12.2 0.3 0.37 10.3 0.3 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.20 EGG10729.1 - 0.15 12.2 2.2 0.27 11.4 0.2 2.3 2 1 0 2 2 2 0 Syntaxin TATR PF03430.8 EGG10730.1 - 2.3 6.7 26.5 0.56 8.7 16.4 1.4 1 1 0 1 1 1 0 Trans-activating transcriptional regulator Rrn6 PF10214.4 EGG10730.1 - 8.2 4.3 46.5 0.42 8.6 15.2 2.1 1 1 1 2 2 2 0 RNA polymerase I-specific transcription-initiation factor GAGA_bind PF06217.7 EGG10730.1 - 8.5 6.2 37.9 0.13 12.1 20.1 2.0 1 1 1 2 2 2 0 GAGA binding protein-like family MIP-T3 PF10243.4 EGG10731.1 - 0.086 11.2 53.5 0.1 11.0 37.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 EGG10731.1 - 0.71 7.5 12.2 0.76 7.4 8.5 1.2 1 0 0 1 1 1 0 Ycf1 RNase_H2-Ydr279 PF09468.5 EGG10731.1 - 1.8 7.7 25.9 4.2 6.4 18.0 1.7 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) U79_P34 PF03064.11 EGG10731.1 - 5.2 6.5 29.1 0.5 9.8 15.6 2.1 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Pox_Ag35 PF03286.9 EGG10731.1 - 7.2 6.0 42.5 0.045 13.2 17.2 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FKBP_C PF00254.23 EGG10732.1 - 1.6e-31 108.1 0.0 3.8e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3714 PF12508.3 EGG10732.1 - 0.0066 15.9 1.1 0.011 15.1 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3714) DUF2360 PF10152.4 EGG10732.1 - 0.14 12.3 3.4 0.21 11.8 2.3 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) NARP1 PF12569.3 EGG10732.1 - 0.16 10.6 9.5 0.22 10.2 6.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MFMR PF07777.6 EGG10732.1 - 0.21 11.4 11.4 0.32 10.9 7.9 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR DUF1764 PF08576.5 EGG10732.1 - 1.5 9.6 9.0 2.5 8.9 6.3 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) KLRAQ PF10205.4 EGG10733.1 - 0.03 14.3 0.8 0.05 13.6 0.5 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein TACI-CRD2 PF09305.5 EGG10734.1 - 0.1 12.3 1.1 7.5 6.4 0.0 2.9 3 0 0 3 3 3 0 TACI, cysteine-rich domain MFS_1 PF07690.11 EGG10739.1 - 3.7e-22 78.5 26.4 5.9e-22 77.8 18.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily LRR_4 PF12799.2 EGG10740.1 - 2.7e-13 49.1 29.2 1.9e-06 27.3 0.3 6.6 5 2 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG10740.1 - 1e-12 47.6 22.7 1e-06 28.3 3.2 4.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_9 PF14580.1 EGG10740.1 - 8.5e-05 22.1 1.3 0.00035 20.1 0.9 1.9 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 EGG10740.1 - 0.001 18.8 27.4 0.34 11.0 0.1 7.9 7 1 1 8 8 8 4 Leucine Rich Repeat SMN PF06003.7 EGG10740.1 - 0.013 14.6 2.3 0.024 13.7 1.6 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) LRR_7 PF13504.1 EGG10740.1 - 0.58 10.5 18.5 70 4.3 0.0 8.3 8 1 1 9 9 9 0 Leucine rich repeat LRR_6 PF13516.1 EGG10740.1 - 4.7 7.5 23.5 8.4 6.8 0.0 7.3 6 1 2 8 8 8 0 Leucine Rich repeat DUF3292 PF11696.3 EGG10741.1 - 2.7e-16 58.6 4.7 1.4e-09 36.4 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3292) FA_desaturase PF00487.19 EGG10741.1 - 0.1 12.0 0.1 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase DUF4401 PF14351.1 EGG10741.1 - 0.41 9.5 3.9 0.59 9.0 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) MmgE_PrpD PF03972.9 EGG10742.1 - 3.3e-155 516.6 0.0 3.7e-155 516.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF1168 PF06658.7 EGG10745.1 - 1.3e-29 102.5 23.4 1.3e-29 102.5 16.2 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1168) Rotavirus_VP1 PF12289.3 EGG10745.1 - 0.12 12.0 0.3 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 Rotavirus VP1 structural protein Cwf_Cwc_15 PF04889.7 EGG10745.1 - 6.4 6.4 25.9 0.99 9.0 15.2 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Rootletin PF15035.1 EGG10746.1 - 0.026 14.5 1.5 0.042 13.8 1.1 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Vps8 PF12816.2 EGG10747.1 - 2.1e-61 206.6 1.1 3.4e-60 202.6 0.1 3.3 4 0 0 4 4 4 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EGG10747.1 - 0.022 14.3 0.1 0.5 9.9 0.0 3.0 3 0 0 3 3 3 0 Region in Clathrin and VPS DUF2207 PF09972.4 EGG10750.1 - 1.6 7.2 4.7 4.7 5.6 0.0 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) F-box-like PF12937.2 EGG10751.1 - 0.029 14.1 0.1 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 F-box-like Inhibitor_I9 PF05922.11 EGG10752.1 - 2.5e-11 43.9 0.0 4.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Arrestin_C PF02752.17 EGG10754.1 - 1.6e-15 57.4 0.1 2.3e-14 53.6 0.0 2.9 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGG10754.1 - 1e-07 31.8 0.2 5e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EGG10754.1 - 0.002 17.6 0.1 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like DUF4512 PF14975.1 EGG10757.1 - 1 10.2 3.3 2.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) Tup_N PF08581.5 EGG10758.1 - 0.00019 21.5 5.1 0.00019 21.5 3.5 5.7 4 2 3 7 7 7 1 Tup N-terminal Reo_sigmaC PF04582.7 EGG10758.1 - 0.57 9.2 21.2 0.87 8.7 0.4 3.8 2 1 3 5 5 5 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 EGG10758.1 - 2.6 7.7 33.0 0.35 10.6 2.6 5.1 2 2 4 7 7 7 0 Laminin Domain II GMC_oxred_N PF00732.14 EGG10759.1 - 1.6e-59 201.4 0.0 2.2e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGG10759.1 - 3.7e-30 105.1 0.0 5.9e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EGG10759.1 - 7.8e-05 21.7 0.5 0.059 12.2 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGG10759.1 - 0.00029 19.8 0.2 0.00042 19.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EGG10759.1 - 0.024 13.5 0.5 2.5 6.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EGG10759.1 - 0.041 13.7 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGG10759.1 - 0.042 12.9 0.1 0.086 11.9 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EGG10759.1 - 0.099 11.2 0.2 0.14 10.7 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.1 EGG10759.1 - 0.14 12.2 0.2 0.36 10.9 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EGG10759.1 - 0.15 12.0 0.0 0.47 10.4 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain ATP-sulfurylase PF01747.12 EGG10761.1 - 2.9e-80 268.6 0.0 5.4e-80 267.7 0.0 1.5 2 0 0 2 2 2 1 ATP-sulfurylase PUA_2 PF14306.1 EGG10761.1 - 3.1e-48 163.1 0.0 4.6e-48 162.6 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.15 EGG10761.1 - 0.0026 17.4 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase HAP1_N PF04849.8 EGG10762.1 - 0.00032 19.7 30.5 0.0033 16.4 8.9 4.4 1 1 0 2 2 2 1 HAP1 N-terminal conserved region Troponin PF00992.15 EGG10762.1 - 0.012 15.6 4.4 0.012 15.6 3.1 4.0 4 0 0 4 4 4 0 Troponin IncA PF04156.9 EGG10762.1 - 0.2 11.2 22.1 1.1 8.7 4.5 3.0 2 0 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 EGG10762.1 - 0.23 9.2 13.5 0.39 8.5 9.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 EGG10762.1 - 2 8.3 9.3 0.59 10.0 3.7 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF607 PF04678.8 EGG10762.1 - 6.7 6.5 9.9 13 5.6 1.4 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Spc7 PF08317.6 EGG10762.1 - 7 5.2 25.0 0.67 8.5 4.0 2.5 1 1 0 2 2 2 0 Spc7 kinetochore protein Acetyltransf_1 PF00583.19 EGG10763.1 - 0.13 12.3 0.1 0.14 12.1 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Gln-synt_C PF00120.19 EGG10764.1 - 1.9e-57 194.4 0.0 2.2e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EGG10764.1 - 4e-17 61.5 0.0 6.9e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF4226 PF10774.4 EGG10765.1 - 0.37 10.8 11.7 8.8 6.4 0.2 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4226) FYVE_2 PF02318.11 EGG10765.1 - 4.1 7.3 15.3 2.3 8.1 1.3 4.0 3 1 1 4 4 4 0 FYVE-type zinc finger RRM_1 PF00076.17 EGG10767.1 - 0.0024 17.4 0.1 0.0058 16.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ARPC4 PF05856.7 EGG10768.1 - 4.6e-69 231.1 0.5 5.1e-69 231.0 0.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) NAD_binding_6 PF08030.7 EGG10769.1 - 2.5e-19 69.6 0.6 4.2e-19 68.9 0.4 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EGG10769.1 - 2.6e-15 56.6 11.6 2.6e-15 56.6 8.0 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGG10769.1 - 1.3e-14 53.9 0.0 1.2e-09 37.9 0.0 2.5 1 1 1 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EGG10769.1 - 1.4e-05 25.6 0.2 0.0042 17.6 0.0 2.4 1 1 0 2 2 2 2 Oxidoreductase NAD-binding domain Cid2 PF09774.4 EGG10773.1 - 1.1e-21 77.5 3.5 1.3e-21 77.2 2.4 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 CGI-121 PF08617.5 EGG10774.1 - 2.7e-35 121.4 6.3 3.2e-35 121.1 4.4 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Taeniidae_ag PF05596.6 EGG10774.1 - 0.033 13.9 0.1 0.082 12.7 0.1 1.7 1 0 0 1 1 1 0 Taeniidae antigen TarH PF02203.10 EGG10774.1 - 0.075 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue Thioredoxin PF00085.15 EGG10775.1 - 2e-26 91.6 0.2 2.7e-26 91.2 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGG10775.1 - 4.1e-07 30.0 0.6 0.0005 20.1 0.0 2.6 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EGG10775.1 - 2.5e-05 24.4 0.2 0.00083 19.5 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EGG10775.1 - 0.00014 21.4 0.2 0.00022 20.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EGG10775.1 - 0.0021 18.0 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EGG10775.1 - 0.0028 17.3 0.2 0.094 12.4 0.0 2.1 1 1 1 2 2 2 1 AhpC/TSA family DIM1 PF02966.11 EGG10775.1 - 0.0048 16.4 0.0 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF953 PF06110.6 EGG10775.1 - 0.0054 16.1 0.2 0.033 13.6 0.2 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Redoxin PF08534.5 EGG10775.1 - 0.0076 15.8 0.2 0.12 11.9 0.1 2.1 1 1 1 2 2 2 1 Redoxin SecY PF00344.15 EGG10776.1 - 2.8e-97 325.7 9.2 2.8e-97 325.7 6.4 1.3 2 0 0 2 2 2 1 SecY translocase Plug_translocon PF10559.4 EGG10776.1 - 3e-20 71.3 0.2 1.2e-19 69.4 0.2 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p UBN2 PF14223.1 EGG10777.1 - 0.004 16.9 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG10777.1 - 0.0064 16.0 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4347 PF14252.1 EGG10777.1 - 0.024 14.1 0.1 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) GAGA PF09237.6 EGG10778.1 - 0.12 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 GAGA factor LEDGF PF11467.3 EGG10779.1 - 0.0069 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) Lactonase PF10282.4 EGG10784.1 - 3e-19 69.3 0.0 4.4e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller zf-CCCH PF00642.19 EGG10785.1 - 3.5e-08 32.9 23.5 0.0001 21.8 4.6 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 EGG10785.1 - 1.1e-07 31.5 8.4 1.1e-07 31.5 5.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGG10785.1 - 3.9e-06 26.3 6.3 8.9e-06 25.2 4.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG10785.1 - 1.3e-05 25.0 8.8 1.3e-05 25.0 6.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG10785.1 - 4.6e-05 22.9 5.1 8.5e-05 22.1 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG10785.1 - 0.00042 19.9 6.4 0.00081 19.0 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGG10785.1 - 0.0077 16.3 4.9 0.041 14.0 3.4 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGG10785.1 - 0.021 14.6 8.4 0.05 13.4 5.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Period_C PF12114.3 EGG10786.1 - 7.4 6.1 16.4 1.4 8.4 4.1 2.1 2 0 0 2 2 2 0 Period protein 2/3C-terminal region OPT PF03169.10 EGG10787.1 - 5.3e-133 444.6 45.5 1.3e-132 443.3 31.6 1.6 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Syntaxin-6_N PF09177.6 EGG10788.1 - 0.13 12.6 0.1 1.3 9.5 0.0 2.4 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Sad1_UNC PF07738.8 EGG10789.1 - 1.5e-28 99.3 0.0 2e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal NADHdeh_related PF10125.4 EGG10789.1 - 0.092 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein THOC7 PF05615.8 EGG10790.1 - 0.022 15.0 0.9 2.2 8.5 0.1 2.6 2 0 0 2 2 2 0 Tho complex subunit 7 DUF3220 PF11516.3 EGG10790.1 - 0.067 13.1 0.0 0.81 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) ORC6 PF05460.8 EGG10790.1 - 0.17 10.9 8.5 0.049 12.7 3.5 1.8 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Barwin PF00967.12 EGG10791.1 - 0.057 13.0 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Barwin family Ribonuc_red_sm PF00268.16 EGG10794.1 - 5.6e-21 74.7 0.1 6.6e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Cut8_C PF08559.5 EGG10797.1 - 0.00016 21.5 0.0 0.00054 19.7 0.0 1.9 1 1 1 2 2 2 1 Cut8 six-helix bundle Cut8_M PF14483.1 EGG10797.1 - 0.00019 21.1 0.4 0.00046 19.9 0.3 1.7 1 0 0 1 1 1 1 Cut8 dimerisation domain CZB PF13682.1 EGG10798.1 - 0.023 14.8 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain NAD4L PF06235.6 EGG10798.1 - 0.044 13.5 1.0 0.059 13.1 0.7 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 4L (NAD4L) Tmemb_cc2 PF10267.4 EGG10798.1 - 0.16 10.4 0.2 0.19 10.2 0.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Ank_2 PF12796.2 EGG10799.1 - 4.9e-24 84.4 0.0 9.9e-14 51.4 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGG10799.1 - 4.5e-22 77.9 1.6 3.7e-12 46.3 0.2 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EGG10799.1 - 5.3e-21 73.3 6.2 6e-07 28.9 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EGG10799.1 - 2.5e-17 61.2 1.2 0.00014 21.7 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EGG10799.1 - 1.1e-16 60.3 1.4 1.8e-07 31.1 0.3 5.1 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Mucin PF01456.12 EGG10799.1 - 0.19 11.4 4.0 0.36 10.5 2.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DIL PF01843.14 EGG10800.1 - 4.5e-22 77.9 2.6 4.5e-22 77.9 1.8 2.1 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.2 EGG10800.1 - 1.2e-14 54.3 0.0 3.3e-13 49.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGG10800.1 - 4e-12 45.2 0.4 1.6e-07 30.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EGG10800.1 - 4.1e-12 45.0 0.3 1.2e-06 28.1 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGG10800.1 - 1.7e-11 43.9 0.2 4.2e-05 23.6 0.1 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGG10800.1 - 9e-11 41.9 0.9 9.6e-07 29.1 0.0 4.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Got1 PF04178.7 EGG10801.1 - 2.8e-17 62.9 13.5 3.5e-17 62.6 9.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family CbiM PF01891.11 EGG10801.1 - 0.64 9.5 6.8 0.76 9.3 4.7 1.1 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region DUF3185 PF11381.3 EGG10801.1 - 2.6 7.8 7.6 11 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) zf-C3HC4_2 PF13923.1 EGG10803.1 - 6.9e-10 38.7 13.3 1.1e-09 38.1 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG10803.1 - 8.1e-09 35.0 9.2 1.2e-08 34.4 6.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGG10803.1 - 6e-08 32.3 12.4 9.9e-08 31.6 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGG10803.1 - 1.9e-07 30.5 11.7 3.5e-07 29.7 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGG10803.1 - 8.1e-07 28.8 13.5 1.6e-06 27.8 9.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGG10803.1 - 2.6e-06 27.0 11.7 4.2e-06 26.3 8.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGG10803.1 - 3.7e-05 23.3 6.9 9.6e-05 22.0 3.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGG10803.1 - 0.00039 20.4 8.7 0.0017 18.4 6.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger U-box PF04564.10 EGG10803.1 - 0.00076 19.3 0.5 0.0061 16.4 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-RING_4 PF14570.1 EGG10803.1 - 0.004 16.7 10.3 0.02 14.4 7.3 1.9 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Trs65 PF12735.2 EGG10803.1 - 0.012 14.9 5.3 0.016 14.5 3.7 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 zf-RING_6 PF14835.1 EGG10803.1 - 0.022 14.5 4.9 0.033 13.9 3.4 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein XAP5 PF04921.9 EGG10803.1 - 0.042 13.4 6.7 0.057 12.9 4.7 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator zf-Nse PF11789.3 EGG10803.1 - 0.091 12.2 5.4 0.21 11.1 3.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit YmzC PF14157.1 EGG10803.1 - 0.099 12.4 3.2 0.35 10.7 0.2 2.4 2 0 0 2 2 2 0 YmzC-like protein zf-Apc11 PF12861.2 EGG10803.1 - 0.14 11.9 5.6 0.37 10.6 3.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EGG10803.1 - 6.3 6.7 10.4 87 3.0 7.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon Glyoxal_oxid_N PF07250.6 EGG10805.1 - 6.3e-46 156.4 0.5 3.1e-43 147.5 0.2 3.0 2 2 0 2 2 2 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EGG10805.1 - 6.4e-24 83.9 0.1 1.5e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EGG10805.1 - 0.01 15.5 1.3 1.2 8.9 0.0 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain AcetylCoA_hydro PF02550.10 EGG10806.1 - 0.0097 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain DUF1770 PF08589.5 EGG10806.1 - 0.14 12.7 0.1 0.27 11.8 0.1 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) PrmA PF06325.8 EGG10807.1 - 2.8e-12 46.3 0.3 5.4e-12 45.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EGG10807.1 - 4.5e-09 36.8 0.0 7.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG10807.1 - 1.5e-08 34.3 0.0 1.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG10807.1 - 3e-08 33.2 0.1 4.6e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGG10807.1 - 2.9e-07 30.5 0.0 5.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG10807.1 - 6.9e-07 29.1 0.0 1.9e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG10807.1 - 1.8e-05 25.0 0.0 3.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG10807.1 - 3.5e-05 24.0 0.0 7.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EGG10807.1 - 0.00017 21.0 0.0 0.0017 17.8 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PRMT5 PF05185.11 EGG10807.1 - 0.0003 19.8 0.0 0.00044 19.2 0.0 1.3 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.4 EGG10807.1 - 0.00036 20.0 0.0 0.00059 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EGG10807.1 - 0.00083 19.3 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 EGG10807.1 - 0.0017 18.0 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG10807.1 - 0.0017 18.8 0.0 0.003 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGG10807.1 - 0.0022 17.1 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 EGG10807.1 - 0.011 14.4 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.14 EGG10807.1 - 0.017 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EGG10807.1 - 0.051 12.6 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase HEAT_2 PF13646.1 EGG10808.1 - 6.7e-07 29.5 2.7 1 9.6 0.0 6.8 6 1 1 7 7 7 2 HEAT repeats HEAT PF02985.17 EGG10808.1 - 5.2e-06 26.1 8.8 0.14 12.2 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EGG10808.1 - 0.0049 17.2 0.0 1.7 9.0 0.0 4.0 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGG10808.1 - 0.056 13.9 5.2 16 6.1 0.0 6.2 5 1 1 6 6 6 0 HEAT-like repeat Ribosomal_60s PF00428.14 EGG10808.1 - 0.7 10.3 0.0 0.7 10.3 0.0 3.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein ChAPs PF09295.5 EGG10809.1 - 2.8e-147 490.6 0.0 1.3e-145 485.1 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.12 EGG10809.1 - 2e-05 24.1 2.7 0.91 9.5 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGG10809.1 - 5e-05 23.5 6.6 0.0035 17.6 0.6 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGG10809.1 - 0.0001 21.8 4.6 0.23 11.1 0.0 3.7 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.1 EGG10809.1 - 0.0006 20.2 7.4 0.95 10.2 0.1 5.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGG10809.1 - 0.0019 17.8 1.9 1.7 8.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGG10809.1 - 0.12 13.0 6.2 5.2 7.8 0.5 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 EGG10809.1 - 0.15 11.0 4.6 1.8 7.5 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGG10809.1 - 2.3 8.2 5.6 20 5.1 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF605 PF04652.11 EGG10809.1 - 3.4 6.9 15.0 5.5 6.2 10.4 1.2 1 0 0 1 1 1 0 Vta1 like Gluconate_2-dh3 PF13618.1 EGG10810.1 - 0.0063 16.6 0.1 0.017 15.2 0.0 1.7 1 1 1 2 2 2 1 Gluconate 2-dehydrogenase subunit 3 TIM21 PF08294.6 EGG10811.1 - 2.3e-05 24.0 0.0 0.00068 19.3 0.0 2.4 2 0 0 2 2 2 2 TIM21 Spore_coat_CotO PF14153.1 EGG10812.1 - 0.0017 17.7 12.3 0.0017 17.7 8.5 3.6 2 1 1 3 3 3 1 Spore coat protein CotO SSP160 PF06933.6 EGG10812.1 - 9.1 4.1 8.7 13 3.6 6.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CaKB PF03185.10 EGG10813.1 - 3.4 6.9 6.6 5.3 6.3 4.6 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Sec1 PF00995.18 EGG10815.1 - 1.6e-145 485.9 0.0 1.8e-145 485.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family O-FucT PF10250.4 EGG10816.1 - 0.00019 20.6 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Matrilin_ccoil PF10393.4 EGG10820.1 - 0.00032 20.0 1.6 0.028 13.7 0.2 3.0 2 1 1 3 3 3 1 Trimeric coiled-coil oligomerisation domain of matrilin Phage_GPO PF05929.6 EGG10820.1 - 0.014 14.7 0.1 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase NPV_P10 PF05531.7 EGG10820.1 - 0.031 14.5 0.8 0.054 13.7 0.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Vac_Fusion PF02346.11 EGG10820.1 - 0.099 12.0 0.1 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus fusion protein DUF148 PF02520.12 EGG10820.1 - 0.14 11.9 0.8 0.19 11.5 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 Cep57_CLD_2 PF14197.1 EGG10820.1 - 0.25 11.3 2.5 0.55 10.2 0.3 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Med9 PF07544.8 EGG10825.1 - 0.0069 16.1 0.3 0.0069 16.1 0.2 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.3 EGG10825.1 - 0.018 15.0 1.9 0.028 14.3 1.3 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex HIT PF01230.18 EGG10826.1 - 2.4e-15 56.8 2.0 4.8e-15 55.8 1.4 1.5 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGG10826.1 - 4.5e-05 23.6 3.3 0.00012 22.2 2.3 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding FlaA PF04620.7 EGG10827.1 - 0.053 12.9 2.8 2.6 7.4 0.5 2.6 2 0 0 2 2 2 0 Flagellar filament outer layer protein Flaa Ras PF00071.17 EGG10830.1 - 2.7e-40 137.3 0.0 8.3e-40 135.8 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGG10830.1 - 3.7e-13 50.0 0.0 5.4e-12 46.2 0.0 2.1 1 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGG10830.1 - 0.0002 20.6 0.0 0.0037 16.5 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.5 EGG10830.1 - 0.0079 15.4 0.0 0.055 12.6 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGG10830.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.6 1 1 1 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 EGG10830.1 - 0.016 14.4 0.0 0.031 13.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 EGG10830.1 - 0.091 11.7 0.0 0.099 11.6 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ACP_syn_III PF08545.5 EGG10830.1 - 0.11 12.2 0.0 3 7.5 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III IIGP PF05049.8 EGG10830.1 - 0.13 11.0 0.0 1.4 7.6 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Ras PF00071.17 EGG10831.1 - 1.9e-38 131.3 0.0 3.6e-38 130.5 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGG10831.1 - 1.1e-08 35.5 0.0 3.7e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGG10831.1 - 0.0095 15.1 0.0 0.021 14.0 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family CRAL_TRIO PF00650.15 EGG10832.1 - 2.3e-22 79.1 0.0 3.3e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Hexapep PF00132.19 EGG10834.1 - 8.9e-07 28.1 8.4 0.00064 19.1 0.2 3.8 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGG10834.1 - 7.8e-06 25.3 2.9 0.0085 15.6 0.3 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Dus PF01207.12 EGG10836.1 - 8.6e-47 159.4 0.0 1.5e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) CENP_C_N PF15622.1 EGG10836.1 - 0.0036 16.5 2.8 0.007 15.6 1.9 1.4 1 0 0 1 1 1 1 Kinetochore assembly subunit CENP-C N-terminal His_Phos_1 PF00300.17 EGG10838.1 - 9.7e-20 71.2 0.0 1.2e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MR_MLE PF01188.16 EGG10838.1 - 0.04 14.4 0.0 0.065 13.7 0.0 1.3 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Aminotran_3 PF00202.16 EGG10839.1 - 1.8e-83 280.2 0.0 2.1e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGG10839.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II tRNA-synt_2b PF00587.20 EGG10840.1 - 1e-36 126.1 0.0 1.3e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGG10840.1 - 2.2e-11 43.5 0.2 5.8e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain Oxidored_molyb PF00174.14 EGG10841.1 - 1.2e-49 168.0 0.0 2.1e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EGG10841.1 - 7.9e-48 161.3 1.1 1e-47 161.0 0.2 1.6 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 EGG10841.1 - 1.3e-28 99.0 0.0 3.5e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGG10841.1 - 3e-26 92.1 0.0 6.6e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EGG10841.1 - 1.2e-19 69.8 0.0 3.2e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EGG10841.1 - 4.9e-09 36.2 0.0 1.8e-07 31.1 0.0 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Atg14 PF10186.4 EGG10842.1 - 3.4e-10 39.3 9.2 6.7e-10 38.3 6.4 1.5 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 AAA PF00004.24 EGG10844.1 - 5.1e-85 282.3 0.0 8.2e-43 145.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGG10844.1 - 9.3e-12 44.8 1.4 5.9e-05 22.8 0.1 4.7 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGG10844.1 - 1.2e-10 40.8 0.0 0.00028 19.9 0.0 3.2 2 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGG10844.1 - 4.1e-10 39.9 1.7 0.0017 18.4 0.1 3.5 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 EGG10844.1 - 2.7e-09 36.2 0.1 0.00025 19.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 EGG10844.1 - 3.7e-09 37.4 0.0 0.0036 18.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EGG10844.1 - 3.8e-09 36.6 0.0 0.00046 20.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGG10844.1 - 4.1e-08 33.4 0.5 0.091 12.9 0.1 4.2 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.1 EGG10844.1 - 1.8e-07 31.1 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGG10844.1 - 2.8e-07 30.6 0.0 0.021 14.9 0.0 3.4 4 0 0 4 4 3 2 RNA helicase AAA_25 PF13481.1 EGG10844.1 - 3.7e-07 29.7 2.1 0.022 14.1 0.1 4.2 2 2 2 4 4 4 1 AAA domain AAA_33 PF13671.1 EGG10844.1 - 3e-06 27.1 0.0 0.0058 16.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 EGG10844.1 - 6.2e-06 25.5 0.3 0.059 12.5 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EGG10844.1 - 1.6e-05 24.4 0.0 0.14 11.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EGG10844.1 - 4e-05 23.6 0.0 0.091 12.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 EGG10844.1 - 4.1e-05 23.2 3.7 0.0043 16.7 0.3 3.2 4 0 0 4 4 2 1 Part of AAA domain AAA_18 PF13238.1 EGG10844.1 - 8.3e-05 22.9 0.2 0.082 13.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.6 EGG10844.1 - 0.0001 21.8 0.1 0.95 9.0 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EGG10844.1 - 0.00011 21.4 0.1 0.51 9.4 0.0 3.4 2 2 2 4 4 4 2 KaiC Rad17 PF03215.10 EGG10844.1 - 0.0011 17.7 0.1 0.036 12.7 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Sigma54_activat PF00158.21 EGG10844.1 - 0.0013 18.2 0.0 2.7 7.4 0.0 3.8 2 2 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 EGG10844.1 - 0.0016 18.4 0.6 2 8.3 0.3 2.6 2 0 0 2 2 2 2 AAA domain SKI PF01202.17 EGG10844.1 - 0.0024 17.7 0.4 0.8 9.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase AAA_24 PF13479.1 EGG10844.1 - 0.0036 16.9 2.4 0.16 11.5 0.3 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EGG10844.1 - 0.0052 16.5 0.1 22 4.6 0.0 3.6 2 2 2 4 4 4 0 Archaeal ATPase Zeta_toxin PF06414.7 EGG10844.1 - 0.0057 15.7 0.1 0.59 9.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Parvo_NS1 PF01057.12 EGG10844.1 - 0.0074 15.1 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 IPT PF01745.11 EGG10844.1 - 0.0083 15.3 0.1 0.52 9.4 0.1 2.4 2 0 0 2 2 2 1 Isopentenyl transferase ABC_tran PF00005.22 EGG10844.1 - 0.01 16.1 0.4 4.1 7.6 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_11 PF13086.1 EGG10844.1 - 0.01 15.4 0.0 0.26 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EGG10844.1 - 0.017 14.3 0.3 0.89 8.7 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Zot PF05707.7 EGG10844.1 - 0.061 12.7 0.2 16 4.9 0.0 3.8 2 2 0 3 3 3 0 Zonular occludens toxin (Zot) NACHT PF05729.7 EGG10844.1 - 0.066 12.8 0.3 5.5 6.6 0.1 3.2 4 0 0 4 4 4 0 NACHT domain PQQ_2 PF13360.1 EGG10845.1 - 6.1e-08 32.4 0.3 0.00032 20.2 0.0 3.2 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.16 EGG10845.1 - 8.4e-06 25.0 1.5 1.1 8.9 0.0 5.4 5 1 0 5 5 5 2 PQQ enzyme repeat DUF1620 PF07774.8 EGG10846.1 - 2.1e-27 95.8 0.0 2.3e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) Exo_endo_phos PF03372.18 EGG10850.1 - 7e-07 29.4 0.1 7.1e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sars6 PF12133.3 EGG10852.1 - 0.032 13.9 0.0 0.094 12.4 0.0 1.8 2 0 0 2 2 2 0 Open reading frame 6 from SARS coronavirus DUF4007 PF13182.1 EGG10853.1 - 0.012 14.5 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) UQ_con PF00179.21 EGG10855.1 - 6.7e-37 126.0 0.2 8.5e-37 125.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Aa_trans PF01490.13 EGG10856.1 - 2.2e-83 280.0 32.7 2.7e-83 279.7 22.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AATF-Che1 PF13339.1 EGG10856.1 - 0.07 13.2 0.3 0.6 10.2 0.4 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor PLU-1 PF08429.6 EGG10857.1 - 0.0013 17.7 1.1 0.0015 17.5 0.7 1.2 1 0 0 1 1 1 1 PLU-1-like protein FAST_2 PF08368.7 EGG10858.1 - 0.0078 16.5 3.7 0.54 10.6 0.1 3.0 2 1 1 3 3 3 1 FAST kinase-like protein, subdomain 2 DUF3161 PF11362.3 EGG10858.1 - 0.012 15.5 0.2 0.39 10.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3161) Frigida PF07899.6 EGG10859.1 - 0.021 13.6 0.3 0.032 12.9 0.2 1.2 1 0 0 1 1 1 0 Frigida-like protein IncA PF04156.9 EGG10859.1 - 0.11 12.0 0.4 0.27 10.8 0.3 1.6 1 0 0 1 1 1 0 IncA protein Plasmodium_Vir PF05795.6 EGG10860.1 - 0.0014 17.9 4.6 0.0017 17.6 3.2 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Nucleo_P87 PF07267.6 EGG10860.1 - 0.12 11.0 7.5 0.14 10.8 5.2 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SID-1_RNA_chan PF13965.1 EGG10860.1 - 0.19 9.8 3.1 0.21 9.6 2.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2215 PF10225.4 EGG10860.1 - 8.3 5.7 7.2 3.4 7.0 0.5 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) RNA_pol_Rpc4 PF05132.9 EGG10860.1 - 8.8 6.3 8.8 1.2 9.0 1.6 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Glyco_transf_20 PF00982.16 EGG10861.1 - 4.4e-182 605.7 0.0 5.1e-182 605.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 EGG10861.1 - 0.11 11.8 0.4 6.1 6.2 0.0 2.6 2 1 0 2 2 2 0 Glycosyl transferases group 1 Glyco_hydro_71 PF03659.9 EGG10863.1 - 1.2e-76 257.6 6.6 1e-75 254.6 4.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 YbjQ_1 PF01906.12 EGG10864.1 - 1.8e-08 34.7 0.0 1.8e-08 34.7 0.0 2.9 3 1 0 3 3 3 1 Putative heavy-metal-binding WD40 PF00400.27 EGG10865.1 - 2.8e-28 96.7 1.9 4.3e-06 26.4 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGG10865.1 - 0.0036 16.7 0.0 0.02 14.3 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1797 PF08796.5 EGG10865.1 - 0.16 11.8 0.1 1.6 8.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) DUF2650 PF10853.3 EGG10869.1 - 0.057 12.8 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) CENP-F_leu_zip PF10473.4 EGG10874.1 - 0.01 15.7 0.6 0.015 15.1 0.4 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LST1 PF05083.8 EGG10874.1 - 0.048 13.6 0.2 0.078 12.9 0.1 1.4 1 1 0 1 1 1 0 LST-1 protein PspB PF06667.7 EGG10880.1 - 0.017 15.0 1.0 0.06 13.2 0.7 1.9 1 0 0 1 1 1 0 Phage shock protein B SPA PF08616.5 EGG10882.1 - 4.3e-07 29.6 0.0 8.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis AIG2 PF06094.7 EGG10883.1 - 1.8e-13 50.8 0.0 5.5e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 AIG2-like family MBOAT_2 PF13813.1 EGG10885.1 - 4e-13 49.2 3.2 4e-13 49.2 2.2 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.1 EGG10886.1 - 7e-16 58.0 3.3 1e-15 57.5 2.3 1.3 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family adh_short PF00106.20 EGG10887.1 - 2.5e-22 79.5 2.3 3.7e-22 78.9 1.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG10887.1 - 7.2e-21 75.0 0.4 9.1e-21 74.7 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG10887.1 - 8.3e-11 41.8 1.0 1.3e-10 41.1 0.7 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGG10887.1 - 0.11 11.9 0.1 0.2 11.0 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Prenyltrans PF00432.16 EGG10888.1 - 5.8e-22 76.9 17.3 1.8e-06 27.3 0.1 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGG10888.1 - 6.8e-18 65.1 0.0 3.8e-15 56.2 0.0 2.8 3 0 0 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGG10888.1 - 0.0018 18.2 0.0 0.009 16.0 0.0 2.0 2 0 0 2 2 2 1 Prenyltransferase-like Ank PF00023.25 EGG10889.1 - 2.2e-05 24.0 0.0 0.1 12.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EGG10889.1 - 6.6e-05 23.1 0.0 0.00027 21.2 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGG10889.1 - 0.0044 17.2 0.0 0.077 13.2 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGG10889.1 - 0.11 13.0 0.0 0.73 10.4 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Transthyretin PF00576.16 EGG10890.1 - 2.9e-31 107.6 0.0 3.2e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family DUF4557 PF15101.1 EGG10891.1 - 0.3 10.8 6.6 0.38 10.5 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) GBP_C PF02841.9 EGG10891.1 - 1.5 7.9 12.4 2 7.5 8.6 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain GAGA_bind PF06217.7 EGG10891.1 - 1.8 8.4 7.7 2.1 8.2 5.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DOR PF14839.1 EGG10891.1 - 4.5 6.9 15.3 6.9 6.3 10.6 1.3 1 0 0 1 1 1 0 DOR family DUF4407 PF14362.1 EGG10891.1 - 6.1 5.7 12.5 7.5 5.4 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RLI PF04068.10 EGG10892.1 - 7.8 6.1 6.9 6 6.5 0.6 2.4 2 0 0 2 2 2 0 Possible Fer4-like domain in RNase L inhibitor, RLI RhoGEF PF00621.15 EGG10893.1 - 2.2e-11 43.9 0.9 2.2e-11 43.9 0.6 3.4 3 1 0 3 3 3 1 RhoGEF domain Glyco_trans_1_3 PF13528.1 EGG10896.1 - 1.3e-09 37.6 0.0 3.8e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 1 RabGAP-TBC PF00566.13 EGG10898.1 - 2.7e-39 134.8 0.1 4.5e-39 134.1 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.13 EGG10899.1 - 5.7e-44 150.1 0.4 9e-44 149.4 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain tRNA-synt_2b PF00587.20 EGG10903.1 - 2.1e-20 73.0 0.0 3.5e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EGG10903.1 - 6.1e-20 70.9 2.3 1.2e-19 69.9 1.6 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EGG10903.1 - 1.2e-17 63.6 0.0 3.9e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain Phage_coat PF09063.5 EGG10903.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phage PP7 coat protein DUF2333 PF10095.4 EGG10905.1 - 0.064 11.8 0.1 0.18 10.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) IncA PF04156.9 EGG10907.1 - 2.1 7.9 14.6 9.1 5.8 10.2 1.9 2 1 0 2 2 2 0 IncA protein Vps55 PF04133.9 EGG10909.1 - 2.2e-39 133.8 7.2 2.4e-39 133.7 5.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Cytochrom_B_N_2 PF13631.1 EGG10909.1 - 0.35 10.6 3.3 0.4 10.4 2.3 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB PEPcase PF00311.12 EGG10910.1 - 1.8 6.2 4.2 2.9 5.6 2.9 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Grp1_Fun34_YaaH PF01184.14 EGG10911.1 - 3.5e-50 170.2 15.0 2.3e-25 89.1 1.5 2.1 2 0 0 2 2 2 2 GPR1/FUN34/yaaH family DUF2244 PF10003.4 EGG10911.1 - 6.8 6.0 6.6 14 4.9 4.6 1.5 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) RNase_PH PF01138.16 EGG10912.1 - 2.6e-18 66.5 0.0 4.1e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGG10912.1 - 2.7e-08 33.6 0.0 6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 FGF-BP1 PF06473.7 EGG10913.1 - 1.8 8.1 12.0 0.09 12.3 2.7 2.1 1 1 1 2 2 2 0 FGF binding protein 1 (FGF-BP1) OST3_OST6 PF04756.8 EGG10914.1 - 2.3e-20 72.7 1.0 3.8e-20 72.0 0.7 1.3 1 0 0 1 1 1 1 OST3 / OST6 family PRCC PF10253.4 EGG10915.1 - 1.9e-24 87.3 20.1 5.7e-24 85.8 11.1 2.8 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF4200 PF13863.1 EGG10915.1 - 0.37 10.7 2.9 0.68 9.8 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) MMR1 PF08505.5 EGG10919.1 - 0.96 9.4 7.9 1.2 9.1 5.5 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF1187 PF06688.6 EGG10919.1 - 2.5 8.3 6.4 2.2 8.4 1.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1187) Daxx PF03344.10 EGG10919.1 - 4.1 5.7 11.5 4.9 5.5 7.9 1.1 1 0 0 1 1 1 0 Daxx Family Vfa1 PF08432.5 EGG10919.1 - 4.6 7.2 8.5 5.7 6.9 5.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HI0933_like PF03486.9 EGG10922.1 - 0.084 11.3 0.1 1.6 7.1 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Fasciclin PF02469.17 EGG10923.1 - 6.9e-23 81.0 1.1 1.4e-12 47.7 0.0 4.9 4 1 0 4 4 4 4 Fasciclin domain DUF4243 PF14027.1 EGG10926.1 - 3.8e-77 259.9 0.8 6.1e-77 259.2 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DnaJ PF00226.26 EGG10927.1 - 3.7e-21 74.6 0.1 6.6e-21 73.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain BNIP2 PF12496.3 EGG10927.1 - 5.4 7.2 7.1 74 3.5 4.9 2.3 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 MBOAT_2 PF13813.1 EGG10928.1 - 1.7e-14 53.6 1.4 1.7e-14 53.6 1.0 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family VPS9 PF02204.13 EGG10929.1 - 6.9e-05 22.8 0.1 9.3e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DMA PF03474.9 EGG10929.1 - 0.0091 15.8 0.7 0.025 14.4 0.0 2.0 2 0 0 2 2 2 1 DMRTA motif DUF830 PF05708.7 EGG10929.1 - 0.097 12.6 0.0 0.29 11.1 0.0 1.7 1 1 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) OTU PF02338.14 EGG10930.1 - 1.2e-05 25.8 0.0 2.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Aldo_ket_red PF00248.16 EGG10932.1 - 7e-76 254.7 0.0 8.6e-76 254.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 EGG10932.1 - 0.12 12.5 0.0 0.73 10.0 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HI0933_like PF03486.9 EGG10934.1 - 0.092 11.1 0.1 1.6 7.0 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Med13_C PF06333.7 EGG10935.1 - 0.0048 15.4 0.5 0.0066 15.0 0.4 1.2 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Phytochelatin_C PF09328.5 EGG10935.1 - 1 8.7 4.2 1.7 8.0 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) Alpha_kinase PF02816.13 EGG10936.1 - 3.6e-06 26.7 0.0 6.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family Tubulin PF00091.20 EGG10938.1 - 6.5e-66 222.2 0.0 8.6e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGG10938.1 - 4.4e-48 162.4 0.0 7.3e-48 161.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGG10938.1 - 0.00048 19.6 0.0 0.00089 18.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF2985 PF11204.3 EGG10939.1 - 1.8e-25 88.4 6.5 3.8e-25 87.4 4.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) TBPIP PF07106.8 EGG10940.1 - 0.014 14.9 2.8 0.076 12.5 0.7 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2247 PF10004.4 EGG10940.1 - 0.018 14.7 0.1 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) Sec10 PF07393.6 EGG10940.1 - 0.035 12.3 4.4 0.044 11.9 3.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 AKNA PF12443.3 EGG10940.1 - 0.037 14.0 2.0 0.14 12.2 1.4 2.0 1 0 0 1 1 1 0 AT-hook-containing transcription factor ATG16 PF08614.6 EGG10940.1 - 0.04 13.7 11.3 0.041 13.6 4.0 2.7 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 EGG10940.1 - 0.089 12.2 4.5 2.8 7.5 0.0 2.6 2 1 0 2 2 2 0 Septum formation initiator DUF3373 PF11853.3 EGG10940.1 - 0.1 11.1 1.5 1.9 6.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) Spc24 PF08286.6 EGG10940.1 - 0.19 11.4 3.3 0.21 11.3 0.6 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1640 PF07798.6 EGG10940.1 - 0.37 10.8 6.3 1.3 9.0 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Rab5-bind PF09311.6 EGG10940.1 - 0.52 10.1 9.4 0.73 9.6 2.5 2.8 2 1 1 3 3 3 0 Rabaptin-like protein IncA PF04156.9 EGG10940.1 - 0.77 9.3 8.5 1.4 8.5 1.3 2.3 2 0 0 2 2 2 0 IncA protein ADIP PF11559.3 EGG10940.1 - 0.87 9.4 10.4 0.18 11.6 1.6 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlxA PF14282.1 EGG10940.1 - 0.94 9.4 9.4 9.5 6.2 2.8 2.6 2 0 0 2 2 2 0 FlxA-like protein Pyr_redox_3 PF13738.1 EGG10941.1 - 9.9e-25 87.7 0.0 3.8e-24 85.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGG10941.1 - 8.1e-09 35.6 0.0 2.5e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGG10941.1 - 3.5e-08 32.7 0.0 2.5e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGG10941.1 - 9.9e-06 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGG10941.1 - 0.027 14.5 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGG10941.1 - 0.048 12.1 0.3 0.64 8.4 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EGG10941.1 - 0.05 12.6 0.1 0.12 11.4 0.1 1.5 1 1 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EGG10941.1 - 0.14 10.9 0.5 0.47 9.2 0.5 1.7 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 EGG10941.1 - 0.19 10.5 0.6 15 4.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Alpha_kinase PF02816.13 EGG10943.1 - 5.1e-06 26.2 0.4 7.8e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 Alpha-kinase family Mif2_N PF15624.1 EGG10944.1 - 6.9 7.2 7.6 20 5.7 4.9 1.8 1 1 1 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Lsr2 PF11774.3 EGG10945.1 - 0.0017 18.2 3.4 0.013 15.3 2.4 2.6 1 0 0 1 1 1 1 Lsr2 PHD PF00628.24 EGG10947.1 - 6.2e-07 29.0 10.8 1.2e-06 28.0 7.5 1.5 1 0 0 1 1 1 1 PHD-finger E7 PF00527.13 EGG10947.1 - 0.74 10.0 6.5 0.19 11.8 0.8 2.8 2 0 0 2 2 2 0 E7 protein, Early protein E1_DerP2_DerF2 PF02221.10 EGG10955.1 - 2e-25 89.6 0.0 2.6e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EGG10955.1 - 0.00022 21.2 0.0 0.0003 20.8 0.0 1.2 1 0 0 1 1 1 1 ML-like domain Acyltransferase PF01553.16 EGG10956.1 - 1.3e-20 73.1 0.0 2e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase E1_DerP2_DerF2 PF02221.10 EGG10957.1 - 5.8e-25 88.0 0.0 7.7e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 ML domain zf-RING_2 PF13639.1 EGG10958.1 - 1.2e-10 41.0 8.2 4.3e-10 39.2 5.7 2.0 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EGG10958.1 - 0.0011 18.8 4.7 0.0024 17.7 2.7 2.0 2 0 0 2 2 2 1 FANCL C-terminal domain zf-rbx1 PF12678.2 EGG10958.1 - 0.0027 17.7 5.2 0.0027 17.7 3.6 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGG10958.1 - 0.0055 16.4 8.8 0.013 15.2 6.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGG10958.1 - 0.012 15.2 5.1 0.036 13.7 3.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG10958.1 - 0.055 13.4 8.3 0.16 12.0 5.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGG10958.1 - 0.12 12.2 4.9 0.45 10.3 3.4 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.1 EGG10958.1 - 0.26 11.4 5.0 4 7.6 3.8 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-C3HC4 PF00097.20 EGG10958.1 - 0.56 9.9 9.1 1.9 8.2 6.3 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EGG10958.1 - 0.69 9.9 8.5 1.9 8.5 5.9 1.8 1 0 0 1 1 1 0 RING-variant domain NUDIX_2 PF13869.1 EGG10959.1 - 3.1e-84 280.9 0.0 3.5e-84 280.8 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Bromodomain PF00439.20 EGG10960.1 - 4.6e-22 77.7 0.0 9.1e-22 76.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EGG10960.1 - 8.4e-13 47.8 0.1 1.9e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 Bromodomain associated PC-Esterase PF13839.1 EGG10963.1 - 1.2e-08 35.1 0.1 3e-07 30.5 0.1 2.1 1 1 1 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Myosin_tail_1 PF01576.14 EGG10963.1 - 0.2 9.3 0.1 0.26 8.9 0.0 1.1 1 0 0 1 1 1 0 Myosin tail Tub_2 PF04525.7 EGG10968.1 - 0.016 14.6 0.1 0.022 14.1 0.1 1.3 1 1 0 1 1 1 0 Tubby C 2 DUF2175 PF09943.4 EGG10971.1 - 0.15 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) U1snRNP70_N PF12220.3 EGG10975.1 - 1.7 9.0 8.4 6.5 7.1 0.8 2.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Sugar_tr PF00083.19 EGG10976.1 - 1.8e-85 287.2 21.4 2.1e-85 287.0 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG10976.1 - 9.9e-24 83.6 39.4 3.3e-18 65.5 9.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGG10976.1 - 0.058 13.4 8.1 0.05 13.6 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) DUF554 PF04474.7 EGG10976.1 - 0.71 8.9 10.0 0.022 13.8 1.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF554) UbiA PF01040.13 EGG10977.1 - 2.4e-19 69.5 1.2 2.6e-19 69.4 0.8 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Cu-oxidase_3 PF07732.10 EGG10979.1 - 2.2e-35 120.9 13.1 1.2e-34 118.5 3.1 4.6 6 1 0 6 6 6 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG10979.1 - 2e-30 105.0 8.5 8.2e-23 80.4 1.0 3.7 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EGG10979.1 - 1.4e-18 67.2 0.5 4.2e-16 59.2 0.0 2.9 2 1 0 2 2 2 2 Multicopper oxidase E1_DerP2_DerF2 PF02221.10 EGG10979.1 - 0.031 14.5 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 ML domain MAD PF05557.8 EGG10980.1 - 0.11 10.5 7.1 0.18 9.8 4.9 1.3 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF3090 PF11290.3 EGG10980.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) PAPA-1 PF04795.7 EGG10982.1 - 1.7 9.3 7.3 2 9.1 5.1 1.1 1 0 0 1 1 1 0 PAPA-1-like conserved region Pox_A11 PF05061.8 EGG10983.1 - 0.46 9.5 2.0 0.64 9.0 1.4 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein CDC45 PF02724.9 EGG10983.1 - 2.4 6.0 7.9 3.7 5.4 5.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4636 PF15468.1 EGG10983.1 - 4 6.8 9.7 0.6 9.5 3.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) SMN PF06003.7 EGG10984.1 - 1.1e-08 34.4 9.6 1.5e-08 34.0 6.7 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) PWWP PF00855.12 EGG10984.1 - 0.00091 19.3 0.3 0.0031 17.6 0.2 2.0 1 1 0 1 1 1 1 PWWP domain TUDOR PF00567.19 EGG10984.1 - 0.0023 17.7 0.0 0.0053 16.5 0.0 1.6 1 1 0 1 1 1 1 Tudor domain LBR_tudor PF09465.5 EGG10984.1 - 0.0091 15.5 0.1 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Hint PF01079.15 EGG10984.1 - 0.047 12.8 0.0 0.1 11.7 0.0 1.5 1 1 0 1 1 1 0 Hint module Rtf2 PF04641.7 EGG10984.1 - 0.2 10.8 13.8 0.039 13.1 1.5 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger BRF1 PF07741.8 EGG10984.1 - 0.2 11.8 16.5 1.2 9.3 1.3 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain PcfK PF14058.1 EGG10984.1 - 0.6 10.2 15.7 0.048 13.8 4.7 2.1 2 0 0 2 2 2 0 PcfK-like protein DUF2201_N PF13203.1 EGG10984.1 - 1.5 7.9 8.7 2.4 7.2 0.7 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain LIM_bind PF01803.11 EGG10984.1 - 2.9 6.9 7.2 1.1 8.3 0.3 2.1 2 0 0 2 2 2 0 LIM-domain binding protein YqfQ PF14181.1 EGG10984.1 - 3.3 7.7 15.0 3 7.8 0.8 2.2 2 0 0 2 2 2 0 YqfQ-like protein RP-C_C PF11800.3 EGG10984.1 - 4.2 7.0 12.4 0.37 10.4 1.0 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF1510 PF07423.6 EGG10984.1 - 7.4 5.8 18.7 5.1 6.4 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) AMP-binding PF00501.23 EGG10985.1 - 6.1e-19 67.7 0.0 1.9e-18 66.0 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EGG10985.1 - 0.0048 17.1 0.0 0.014 15.6 0.0 1.9 1 1 0 1 1 1 1 Phosphopantetheine attachment site WHIM2 PF15613.1 EGG10986.1 - 7.1e-05 22.5 0.0 0.00021 21.1 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EGG10986.1 - 0.15 11.8 1.4 0.23 11.2 0.1 1.9 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 Opi1 PF08618.5 EGG10986.1 - 0.69 8.7 6.6 0.87 8.4 4.6 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 CENP-B_dimeris PF09026.5 EGG10987.1 - 1.3 9.3 6.9 1.6 8.9 0.5 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CorA PF01544.13 EGG10988.1 - 0.0093 15.0 0.6 0.0093 15.0 0.4 1.3 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Tropomyosin_1 PF12718.2 EGG10988.1 - 0.027 14.3 7.6 0.041 13.7 5.2 1.3 1 1 0 1 1 1 0 Tropomyosin like IncA PF04156.9 EGG10988.1 - 0.048 13.2 9.4 0.12 11.9 6.5 1.6 1 1 0 1 1 1 0 IncA protein AATF-Che1 PF13339.1 EGG10988.1 - 0.057 13.5 3.3 0.078 13.1 2.3 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Nnf1 PF03980.9 EGG10988.1 - 0.094 12.7 5.8 0.17 11.9 3.9 1.6 1 1 0 1 1 1 0 Nnf1 Prok-TraM PF09228.5 EGG10988.1 - 0.13 12.4 2.1 0.23 11.6 1.4 1.6 1 1 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM TPK_catalytic PF04263.11 EGG10988.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain TPR_MLP1_2 PF07926.7 EGG10988.1 - 0.15 11.7 10.2 3.6 7.3 6.0 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ABC_tran_2 PF12848.2 EGG10988.1 - 0.33 10.8 8.7 0.11 12.3 4.1 1.6 2 0 0 2 2 2 0 ABC transporter TMCO5 PF14992.1 EGG10988.1 - 0.71 8.9 9.8 0.84 8.7 6.8 1.1 1 0 0 1 1 1 0 TMCO5 family Uds1 PF15456.1 EGG10988.1 - 1.2 9.1 6.4 1.2 9.1 3.3 1.7 1 1 1 2 2 2 0 Up-regulated During Septation Seryl_tRNA_N PF02403.17 EGG10988.1 - 1.3 9.1 8.2 3.4 7.7 5.7 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 EGG10988.1 - 2.3 7.0 8.6 2.5 6.9 6.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IBN_N PF03810.14 EGG10990.1 - 2.3e-11 43.4 0.0 3.5e-11 42.8 0.0 1.4 1 1 0 1 1 1 1 Importin-beta N-terminal domain Aminotran_3 PF00202.16 EGG10991.1 - 4.8e-07 28.9 0.0 8e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III DUF2433 PF10360.4 EGG10992.1 - 7e-36 123.4 0.0 2.6e-35 121.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2433) zf-C3HC4 PF00097.20 EGG10995.1 - 0.0048 16.5 12.6 0.3 10.7 5.0 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGG10995.1 - 0.014 15.2 14.0 0.053 13.3 4.3 2.5 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 EGG10995.1 - 0.04 13.9 13.2 0.43 10.6 4.3 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG10995.1 - 0.23 11.2 12.1 1.1 9.0 3.8 2.7 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 EGG10995.1 - 4.7 6.8 17.7 0.59 9.7 5.5 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain TniQ PF06527.6 EGG10995.1 - 6.2 7.0 7.9 0.47 10.6 0.8 2.1 1 1 1 2 2 2 0 TniQ zf-RING_2 PF13639.1 EGG10996.1 - 0.00028 20.6 3.9 0.00028 20.6 2.7 1.7 2 0 0 2 2 2 1 Ring finger domain zf-UDP PF14569.1 EGG10996.1 - 0.0093 15.6 0.8 0.11 12.2 0.1 2.1 1 1 1 2 2 2 1 Zinc-binding RING-finger Heme_oxygenase PF01126.15 EGG10996.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 Heme oxygenase zf-C3HC4_3 PF13920.1 EGG10996.1 - 0.061 13.0 1.6 0.14 11.8 1.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FUSC PF04632.7 EGG10996.1 - 0.2 10.0 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-RING_4 PF14570.1 EGG10996.1 - 0.23 11.0 4.0 0.45 10.1 2.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EGG10996.1 - 4.6 7.0 9.0 0.73 9.6 3.3 1.9 2 1 0 2 2 2 0 zinc-RING finger domain Asp-B-Hydro_N PF05279.6 EGG10998.1 - 0.056 13.2 2.0 0.082 12.7 1.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MCPVI PF02993.9 EGG10998.1 - 6 6.9 7.9 10 6.1 5.5 1.3 1 0 0 1 1 1 0 Minor capsid protein VI zf-RING_2 PF13639.1 EGG10999.1 - 2.3e-05 24.1 7.7 3.9e-05 23.3 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGG10999.1 - 0.0061 16.5 9.4 0.0097 15.9 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG10999.1 - 0.0074 15.9 6.1 0.013 15.1 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG10999.1 - 0.032 13.9 9.4 0.061 13.0 6.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Amb_V_allergen PF03913.8 EGG10999.1 - 0.61 9.8 2.6 1.1 9.0 1.8 1.4 1 0 0 1 1 1 0 Amb V Allergen zf-C3HC4 PF00097.20 EGG10999.1 - 1.7 8.3 9.8 3 7.5 6.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Methyltransf_11 PF08241.7 EGG11000.1 - 7e-08 32.8 0.0 1.2e-06 28.9 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG11000.1 - 1.9e-05 24.4 0.0 4.8e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG11000.1 - 6.2e-05 23.4 0.9 0.00051 20.4 0.1 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG11000.1 - 7.8e-05 22.3 0.1 0.00049 19.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG11000.1 - 0.0072 16.6 0.0 0.064 13.6 0.0 2.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG11000.1 - 0.057 14.0 0.2 1.3 9.6 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain zf-RING_2 PF13639.1 EGG11001.1 - 0.00052 19.7 6.9 0.00079 19.2 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGG11001.1 - 1.3 9.0 6.5 2.3 8.3 4.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG11001.1 - 1.8 8.3 7.1 2.9 7.6 4.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain CTP_transf_2 PF01467.21 EGG11003.1 - 1.1e-12 48.3 0.0 1.2e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase ORF6C PF10552.4 EGG11003.1 - 0.13 11.9 0.0 4.1 7.1 0.0 2.1 1 1 1 2 2 2 0 ORF6C domain Zn_clus PF00172.13 EGG11004.1 - 4.7e-07 29.6 7.2 8e-07 28.8 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGG11004.1 - 7.9e-05 21.6 0.1 0.00028 19.8 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-RING_2 PF13639.1 EGG11005.1 - 3.6e-08 33.1 3.3 7.6e-08 32.0 2.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGG11005.1 - 0.0017 18.3 4.4 0.0017 18.3 3.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG11005.1 - 0.065 12.9 3.3 0.15 11.8 2.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF2175 PF09943.4 EGG11005.1 - 0.1 12.6 0.6 0.32 11.0 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_3 PF13920.1 EGG11005.1 - 0.54 9.9 4.9 0.28 10.9 1.2 2.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MRP-L51 PF10244.4 EGG11006.1 - 0.065 13.2 0.0 3 7.9 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit DNA_ligase_ZBD PF03119.11 EGG11007.1 - 0.053 13.2 0.6 4.5 7.0 0.0 3.1 2 1 1 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain SH3_1 PF00018.23 EGG11008.1 - 6.1e-13 47.9 0.1 1.1e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGG11008.1 - 8e-12 44.4 0.0 1.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EGG11008.1 - 4.4e-11 42.1 0.0 7.7e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PAP1 PF08601.5 EGG11008.1 - 0.75 9.4 17.9 1 8.9 12.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 RRM_6 PF14259.1 EGG11009.1 - 2.9e-22 78.4 0.0 3.1e-12 46.2 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGG11009.1 - 3.5e-22 77.8 0.5 2.2e-13 49.6 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG11009.1 - 2.3e-09 36.9 0.0 0.00034 20.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGG11009.1 - 0.0001 22.0 0.0 0.00038 20.1 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Spore_coat_CotO PF14153.1 EGG11009.1 - 3 7.2 22.7 0.46 9.8 3.0 2.4 2 0 0 2 2 2 0 Spore coat protein CotO Myc_N PF01056.13 EGG11009.1 - 3.4 6.7 19.1 0.051 12.7 7.1 2.1 2 0 0 2 2 2 0 Myc amino-terminal region DUF4576 PF15144.1 EGG11010.1 - 0.08 12.5 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) FmrO PF07091.6 EGG11011.1 - 0.16 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) GHL1-3 PF11308.3 EGG11012.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 zf-met PF12874.2 EGG11015.1 - 2.1e-06 27.7 2.7 2.7e-06 27.3 0.6 2.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 EGG11015.1 - 0.00018 21.0 0.1 0.00028 20.4 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cullin PF00888.17 EGG11016.1 - 1.3e-143 479.6 1.8 1.6e-143 479.3 1.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGG11016.1 - 4.2e-25 87.3 3.3 4.6e-25 87.2 0.8 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 EGG11016.1 - 0.0016 18.5 0.1 0.0066 16.5 0.1 2.2 1 0 0 1 1 1 1 Penicillinase repressor HTH_34 PF13601.1 EGG11016.1 - 0.063 13.3 0.0 0.89 9.6 0.0 2.6 3 0 0 3 3 3 0 Winged helix DNA-binding domain Methyltransf_11 PF08241.7 EGG11017.1 - 1.5e-10 41.4 0.0 3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG11017.1 - 7.9e-09 35.4 0.0 1.9e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGG11017.1 - 3.2e-08 32.9 0.0 6.3e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGG11017.1 - 4.5e-08 32.8 0.0 1.1e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG11017.1 - 6.9e-08 32.7 0.0 1.8e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG11017.1 - 7.5e-05 23.1 0.0 0.00035 20.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Filament PF00038.16 EGG11017.1 - 0.0017 17.8 0.7 0.0017 17.8 0.5 1.7 2 0 0 2 2 2 1 Intermediate filament protein Methyltransf_18 PF12847.2 EGG11017.1 - 0.0063 17.0 0.0 0.021 15.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Paired_CXXCH_1 PF09699.5 EGG11020.1 - 1.8 8.1 6.9 0.12 11.9 0.5 2.3 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) MAGE_N PF12440.3 EGG11022.1 - 3.9 7.8 6.0 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal DUF3278 PF11683.3 EGG11024.1 - 0.49 10.4 6.8 0.83 9.6 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) SecG PF03840.9 EGG11026.1 - 0.18 11.5 3.8 0.66 9.7 2.7 1.9 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Nefa_Nip30_N PF10187.4 EGG11028.1 - 2.2e-28 98.4 17.5 2.4e-28 98.2 12.1 1.0 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2216 PF10226.4 EGG11028.1 - 0.032 13.7 3.2 0.043 13.3 2.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) DUF2075 PF09848.4 EGG11028.1 - 0.18 10.7 2.3 0.17 10.8 0.9 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Elongin_A PF06881.6 EGG11028.1 - 0.36 11.2 8.3 0.29 11.5 4.3 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A BTV_NS2 PF04514.7 EGG11028.1 - 0.64 8.8 7.1 0.083 11.7 2.2 1.5 1 1 1 2 2 2 0 Bluetongue virus non-structural protein NS2 NPL4 PF05021.10 EGG11031.1 - 2e-98 329.3 0.0 3.4e-98 328.5 0.0 1.4 1 1 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EGG11031.1 - 1.5e-65 219.3 0.2 2.4e-65 218.6 0.2 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EGG11031.1 - 1.5e-05 25.1 0.0 2.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 DZR PF12773.2 EGG11031.1 - 0.057 13.2 0.3 0.057 13.2 0.2 2.8 3 0 0 3 3 3 0 Double zinc ribbon EF_assoc_1 PF08355.7 EGG11031.1 - 0.067 12.4 0.0 0.19 11.0 0.0 1.7 1 0 0 1 1 1 0 EF hand associated zf-RanBP PF00641.13 EGG11031.1 - 3.2 6.9 7.4 0.074 12.1 0.4 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Pectinesterase PF01095.14 EGG11032.1 - 2.6e-35 121.4 0.1 3e-35 121.2 0.1 1.0 1 0 0 1 1 1 1 Pectinesterase CCDC-167 PF15188.1 EGG11035.1 - 0.0095 15.8 0.2 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 TPR_6 PF13174.1 EGG11035.1 - 0.15 12.5 0.5 0.54 10.8 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Phytochelatin PF05023.9 EGG11036.1 - 6.2e-78 260.6 0.0 7e-78 260.4 0.0 1.0 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.1 EGG11036.1 - 0.0063 16.8 0.0 0.085 13.2 0.0 2.3 1 1 0 1 1 1 1 Peptidase_C39 like family HTH_21 PF13276.1 EGG11037.1 - 0.00012 22.0 3.4 0.00084 19.3 0.5 2.9 3 0 0 3 3 3 1 HTH-like domain HTH_32 PF13565.1 EGG11037.1 - 0.0002 22.1 1.4 0.18 12.6 0.0 3.4 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.1 EGG11037.1 - 0.021 14.3 0.7 33 4.1 0.0 4.1 4 0 0 4 4 4 0 Winged helix-turn helix RecX PF02631.11 EGG11037.1 - 0.021 15.0 0.2 0.042 14.0 0.0 1.5 2 0 0 2 2 2 0 RecX family RRF PF01765.14 EGG11038.1 - 0.053 12.9 0.2 0.071 12.5 0.1 1.1 1 0 0 1 1 1 0 Ribosome recycling factor DnaJ PF00226.26 EGG11040.1 - 2.1e-12 46.5 0.0 8.4e-12 44.6 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.1 EGG11040.1 - 2.8e-06 27.5 1.0 0.069 13.4 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGG11040.1 - 8.5e-05 23.1 2.1 0.27 11.9 0.4 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGG11040.1 - 0.00056 19.5 4.2 0.14 11.8 0.8 2.7 2 0 0 2 2 2 2 TPR repeat Apc3 PF12895.2 EGG11040.1 - 0.00093 19.2 6.5 0.41 10.8 0.2 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGG11040.1 - 0.015 15.8 1.1 44 5.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGG11040.1 - 0.043 13.7 9.1 7.3 6.7 0.6 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGG11040.1 - 0.045 13.7 0.7 5.2 7.1 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGG11040.1 - 0.19 11.5 4.5 3.4 7.6 0.1 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGG11040.1 - 0.2 12.1 1.7 22 5.8 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Drf_DAD PF06345.6 EGG11040.1 - 0.3 10.9 2.6 0.27 11.0 0.2 2.3 2 0 0 2 2 2 0 DRF Autoregulatory Domain TPR_6 PF13174.1 EGG11040.1 - 0.97 10.0 6.7 1.3 9.6 0.1 3.7 4 1 0 4 4 3 0 Tetratricopeptide repeat Spc7 PF08317.6 EGG11042.1 - 0.016 13.9 0.1 0.025 13.2 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF362 PF04015.7 EGG11042.1 - 0.084 12.3 0.1 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF362) CCDC-167 PF15188.1 EGG11043.1 - 0.0021 17.9 2.1 0.0078 16.1 1.5 1.9 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 167 Peptidase_M15_3 PF08291.6 EGG11045.1 - 0.00046 19.9 1.3 0.21 11.3 0.2 2.4 1 1 1 2 2 2 2 Peptidase M15 zf-HC2 PF13490.1 EGG11045.1 - 0.0045 16.8 0.2 4 7.4 0.0 2.8 2 0 0 2 2 2 2 Putative zinc-finger MSA-2c PF12238.3 EGG11045.1 - 0.032 13.9 2.5 0.14 11.8 0.3 2.1 1 1 1 2 2 2 0 Merozoite surface antigen 2c Toxin_YhaV PF11663.3 EGG11045.1 - 0.74 9.5 4.6 9 6.0 0.2 2.2 1 1 1 2 2 2 0 Toxin with endonuclease activity YhaV CP12 PF02672.10 EGG11045.1 - 1.9 9.0 4.9 3.7 8.0 0.6 2.5 1 1 1 2 2 2 0 CP12 domain YscJ_FliF_C PF08345.6 EGG11045.1 - 2.8 7.8 8.4 15 5.5 2.6 2.2 1 1 1 2 2 2 0 Flagellar M-ring protein C-terminal DUF947 PF06102.7 EGG11045.1 - 3 7.6 11.2 0.65 9.8 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF947) DUF4218 PF13960.1 EGG11046.1 - 0.0015 17.9 0.1 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) AAA_13 PF13166.1 EGG11047.1 - 0.014 13.8 6.3 0.021 13.2 4.4 1.1 1 0 0 1 1 1 0 AAA domain Prominin PF05478.6 EGG11047.1 - 0.024 12.1 2.3 0.033 11.7 1.6 1.3 1 0 0 1 1 1 0 Prominin IncA PF04156.9 EGG11047.1 - 0.032 13.8 14.8 0.2 11.2 10.0 2.2 1 1 0 1 1 1 0 IncA protein HSBP1 PF06825.7 EGG11047.1 - 0.096 12.2 4.9 45 3.7 0.1 4.3 4 0 0 4 4 4 0 Heat shock factor binding protein 1 COG2 PF06148.6 EGG11047.1 - 0.16 11.8 6.1 0.27 11.1 0.7 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Med9 PF07544.8 EGG11047.1 - 0.23 11.2 8.0 1.9 8.2 0.0 3.5 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.7 EGG11047.1 - 0.61 10.3 6.0 5.2 7.4 1.0 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 EGG11047.1 - 0.86 7.3 3.8 1.3 6.7 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EGG11047.1 - 1 9.7 9.9 0.51 10.7 2.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4164 PF13747.1 EGG11047.1 - 1.3 9.1 14.6 0.71 10.0 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) FH2 PF02181.18 EGG11047.1 - 6.2 5.5 10.1 4.2 6.1 2.6 2.4 1 1 2 3 3 3 0 Formin Homology 2 Domain MHCassoc_trimer PF08831.5 EGG11049.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Ceramidase PF05875.7 EGG11053.1 - 4.7e-78 261.9 10.8 5.4e-78 261.7 7.5 1.0 1 0 0 1 1 1 1 Ceramidase MnhB PF04039.8 EGG11053.1 - 0.55 10.3 4.7 0.63 10.1 0.4 2.5 3 0 0 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter Arv1 PF04161.8 EGG11053.1 - 4.2 7.2 6.5 0.69 9.7 1.1 2.0 2 1 0 2 2 2 0 Arv1-like family DPBB_1 PF03330.13 EGG11055.1 - 1.3e-06 28.3 0.8 8.8e-06 25.6 0.6 2.3 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Nop14 PF04147.7 EGG11055.1 - 0.068 11.0 4.1 0.081 10.8 2.9 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.7 EGG11055.1 - 0.15 10.4 4.7 0.19 10.0 3.3 1.0 1 0 0 1 1 1 0 Mpp10 protein Nucleoplasmin PF03066.10 EGG11055.1 - 0.18 11.3 3.1 0.32 10.5 2.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin Trypan_PARP PF05887.6 EGG11055.1 - 0.39 10.5 11.3 0.8 9.5 7.8 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2457 PF10446.4 EGG11055.1 - 0.57 8.8 10.6 0.82 8.3 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 EGG11055.1 - 1.6 8.9 9.6 2.8 8.2 6.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Dicty_REP PF05086.7 EGG11055.1 - 3.2 5.4 5.0 0.58 7.8 0.0 1.8 1 1 1 2 2 2 0 Dictyostelium (Slime Mold) REP protein SNARE_assoc PF09335.6 EGG11056.1 - 1.1e-14 54.7 2.6 1.1e-14 54.7 1.8 1.4 2 0 0 2 2 2 1 SNARE associated Golgi protein ARID PF01388.16 EGG11059.1 - 1.2e-13 50.7 0.3 8.4e-13 47.9 0.0 2.8 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PP2C PF00481.16 EGG11060.1 - 3.2e-67 226.6 0.0 4.1e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Peptidase_M14 PF00246.19 EGG11060.1 - 0.0059 16.2 0.0 0.0091 15.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase NIR_SIR PF01077.17 EGG11061.1 - 5.7e-50 168.7 0.0 1.2e-45 154.6 0.0 2.8 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EGG11061.1 - 2.6e-26 91.0 0.0 2e-13 49.7 0.0 3.0 2 1 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EGG11061.1 - 2.7e-26 92.3 0.0 5.1e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin OmpH PF03938.9 EGG11061.1 - 0.11 12.3 6.1 3.2 7.6 4.8 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DNA_RNApol_7kD PF03604.8 EGG11062.1 - 7.6e-15 54.0 9.6 9.8e-15 53.7 6.7 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.5 EGG11062.1 - 0.0017 17.7 2.5 0.0031 16.9 1.7 1.4 1 0 0 1 1 1 1 A2L zinc ribbon domain DZR PF12773.2 EGG11062.1 - 0.022 14.5 1.2 0.031 14.0 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 EGG11062.1 - 0.059 13.0 1.2 0.07 12.8 0.8 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ISL3 PF14690.1 EGG11062.1 - 0.061 13.3 4.2 0.33 11.0 0.6 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-Mss51 PF13824.1 EGG11062.1 - 0.13 12.0 0.5 4.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 TFIIS_C PF01096.13 EGG11062.1 - 0.26 10.9 2.6 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-dskA_traR PF01258.12 EGG11062.1 - 0.37 10.5 6.4 2 8.2 1.7 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Zn-ribbon_8 PF09723.5 EGG11062.1 - 0.62 10.0 5.8 1.6 8.7 4.0 1.7 1 1 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_recom PF13408.1 EGG11062.1 - 0.64 10.3 3.9 4.1 7.7 1.1 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-trcl PF13451.1 EGG11062.1 - 1.9 8.2 7.6 4.7 6.9 0.1 2.2 1 1 1 2 2 2 0 Probable zinc-binding domain TF_Zn_Ribbon PF08271.7 EGG11062.1 - 3.7 6.9 6.3 12 5.3 4.4 1.8 1 1 0 1 1 1 0 TFIIB zinc-binding ADK_lid PF05191.9 EGG11062.1 - 4.7 6.9 7.3 24 4.6 5.1 1.9 1 1 0 1 1 1 0 Adenylate kinase, active site lid Ribosomal_L44 PF00935.14 EGG11062.1 - 7.7 6.6 7.9 1e+02 3.0 5.4 2.5 1 1 0 1 1 1 0 Ribosomal protein L44 COX15-CtaA PF02628.10 EGG11063.1 - 5.3e-07 28.7 0.1 5.5e-07 28.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein ORC6 PF05460.8 EGG11064.1 - 0.059 12.4 3.6 0.082 11.9 2.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) IncA PF04156.9 EGG11067.1 - 0.00018 21.1 7.2 0.00025 20.6 5.0 1.3 1 0 0 1 1 1 1 IncA protein FlaC_arch PF05377.6 EGG11067.1 - 0.0063 16.3 1.7 0.066 13.1 0.1 2.7 3 1 0 3 3 2 1 Flagella accessory protein C (FlaC) DUF3584 PF12128.3 EGG11067.1 - 0.0095 13.3 9.5 0.01 13.1 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF3450 PF11932.3 EGG11067.1 - 0.015 14.6 6.1 0.018 14.2 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Mnd1 PF03962.10 EGG11067.1 - 0.018 14.7 10.8 0.025 14.2 7.5 1.1 1 0 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 EGG11067.1 - 0.021 13.2 4.7 0.024 13.0 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MADF_DNA_bdg PF10545.4 EGG11067.1 - 0.026 14.7 0.6 0.026 14.7 0.4 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like APG6 PF04111.7 EGG11067.1 - 0.028 13.4 11.7 0.038 13.0 8.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 F-actin_cap_A PF01267.12 EGG11067.1 - 0.035 13.1 4.1 0.052 12.5 2.9 1.4 1 1 0 1 1 1 0 F-actin capping protein alpha subunit Reo_sigmaC PF04582.7 EGG11067.1 - 0.039 13.1 0.1 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CCDC155 PF14662.1 EGG11067.1 - 0.067 12.7 8.5 0.085 12.4 5.9 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Lectin_N PF03954.9 EGG11067.1 - 0.067 12.5 3.1 0.53 9.6 1.1 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain V_ATPase_I PF01496.14 EGG11067.1 - 0.081 10.7 5.2 0.093 10.5 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 EGG11067.1 - 0.081 12.6 9.4 0.2 11.4 2.4 2.3 2 0 0 2 2 2 0 Prefoldin subunit Paramyxo_P PF01806.12 EGG11067.1 - 0.083 12.1 3.5 0.12 11.6 2.4 1.3 1 1 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region FUN14 PF04930.10 EGG11067.1 - 0.12 12.6 4.1 0.82 9.9 2.8 2.1 1 1 0 1 1 1 0 FUN14 family Seryl_tRNA_N PF02403.17 EGG11067.1 - 0.15 12.0 9.6 0.45 10.5 6.3 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.1 EGG11067.1 - 0.24 10.2 3.9 0.3 9.9 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin_2 PF14523.1 EGG11067.1 - 0.27 11.3 9.9 0.087 12.8 3.8 2.1 1 1 1 2 2 2 0 Syntaxin-like protein Snapin_Pallidin PF14712.1 EGG11067.1 - 0.29 11.4 4.6 0.46 10.8 2.4 1.9 1 1 0 1 1 1 0 Snapin/Pallidin HemX PF04375.9 EGG11067.1 - 0.32 9.5 5.0 0.39 9.2 3.4 1.2 1 0 0 1 1 1 0 HemX TMF_TATA_bd PF12325.3 EGG11067.1 - 0.42 10.3 7.9 0.93 9.2 5.4 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 EGG11067.1 - 0.51 10.2 11.3 1.9 8.3 7.0 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3885 PF13021.1 EGG11067.1 - 0.6 9.8 2.6 1.8 8.2 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3885) DUF883 PF05957.8 EGG11067.1 - 0.77 10.1 4.2 8.1 6.9 0.9 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) TPR_MLP1_2 PF07926.7 EGG11067.1 - 0.89 9.3 14.1 2.2 8.0 9.7 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prefoldin PF02996.12 EGG11067.1 - 0.96 9.1 7.9 0.48 10.0 3.0 2.1 1 1 1 2 2 2 0 Prefoldin subunit Phage_GP20 PF06810.6 EGG11067.1 - 1 8.7 14.0 1.9 7.9 5.6 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 DivIC PF04977.10 EGG11067.1 - 1.1 8.8 7.3 0.53 9.8 2.8 2.1 1 1 1 2 2 2 0 Septum formation initiator GrpE PF01025.14 EGG11067.1 - 1.4 8.4 10.9 4.4 6.8 7.5 1.8 1 1 0 1 1 1 0 GrpE TMPIT PF07851.8 EGG11067.1 - 2.3 7.2 7.9 3.2 6.7 5.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein CENP-Q PF13094.1 EGG11067.1 - 3.3 7.7 13.9 18 5.3 6.9 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FliD_C PF07195.7 EGG11067.1 - 3.8 6.7 7.7 1.6 8.0 1.6 2.1 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus UPF0118 PF01594.11 EGG11069.1 - 0.03 13.3 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 Polysacc_synt_3 PF13440.1 EGG11069.1 - 0.034 13.5 0.1 0.045 13.2 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FYVE_2 PF02318.11 EGG11074.1 - 0.35 10.7 2.8 0.46 10.4 1.9 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger DUF2448 PF10476.4 EGG11076.1 - 0.033 13.7 0.1 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) GCIP PF13324.1 EGG11076.1 - 0.1 11.8 1.1 0.1 11.7 0.8 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Ribosomal_S17e PF00833.13 EGG11076.1 - 0.11 12.2 0.5 0.17 11.6 0.3 1.5 1 1 0 1 1 1 0 Ribosomal S17 Z1 PF10593.4 EGG11076.1 - 0.16 11.1 1.9 0.2 10.8 1.1 1.3 1 1 0 1 1 1 0 Z1 domain DUF4515 PF14988.1 EGG11076.1 - 0.17 11.5 4.8 0.05 13.2 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) V_ATPase_I PF01496.14 EGG11076.1 - 0.21 9.3 1.6 0.25 9.1 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF507 PF04368.8 EGG11076.1 - 0.34 10.5 3.6 0.35 10.4 1.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF507) DUF935 PF06074.7 EGG11077.1 - 0.36 9.4 1.8 0.21 10.2 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF935) Actin PF00022.14 EGG11078.1 - 1.7e-22 79.4 0.0 3.7e-22 78.2 0.0 1.4 1 1 0 1 1 1 1 Actin Glyco_hydro_12 PF01670.11 EGG11080.1 - 5.1e-14 52.3 0.4 7.3e-14 51.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 THUMP PF02926.12 EGG11082.1 - 2.7e-05 24.1 0.2 8.8e-05 22.4 0.1 2.1 1 1 0 1 1 1 1 THUMP domain DUF1433 PF07252.6 EGG11082.1 - 0.041 14.1 0.3 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1433) Glutaredoxin PF00462.19 EGG11083.1 - 5.1e-19 68.0 0.0 1.7e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EGG11083.1 - 1e-10 41.2 0.0 2.4e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin SH3BGR PF04908.10 EGG11083.1 - 0.0015 18.4 0.0 0.0044 16.9 0.0 1.7 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Thioredoxin_8 PF13905.1 EGG11083.1 - 0.025 14.6 0.1 14 5.9 0.0 3.2 2 1 1 3 3 3 0 Thioredoxin-like HyaE PF07449.6 EGG11083.1 - 0.028 14.2 0.0 3 7.7 0.0 2.6 2 1 1 3 3 3 0 Hydrogenase-1 expression protein HyaE Fe-ADH PF00465.14 EGG11083.1 - 0.16 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase bZIP_1 PF00170.16 EGG11084.1 - 0.019 14.9 1.3 0.036 14.0 0.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF2670 PF10875.3 EGG11085.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) COG2 PF06148.6 EGG11089.1 - 0.043 13.6 6.7 0.13 12.1 0.7 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DASH_Dam1 PF08653.5 EGG11089.1 - 0.089 12.5 0.3 4.3 7.1 0.0 2.9 2 1 0 2 2 2 0 DASH complex subunit Dam1 Prominin PF05478.6 EGG11089.1 - 0.11 10.0 5.9 0.15 9.5 4.1 1.2 1 0 0 1 1 1 0 Prominin DUF4164 PF13747.1 EGG11089.1 - 0.11 12.6 12.7 0.33 11.1 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Med9 PF07544.8 EGG11089.1 - 0.14 11.9 9.0 1.2 8.9 0.1 3.6 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EGG11089.1 - 0.21 11.1 18.6 0.094 12.3 9.4 2.6 2 1 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 EGG11089.1 - 0.25 9.1 3.3 0.37 8.6 2.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 EGG11089.1 - 0.34 11.1 6.8 2.3 8.5 1.2 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 EGG11089.1 - 0.52 10.1 13.2 0.13 12.0 4.6 2.3 1 1 1 2 2 2 0 Tropomyosin like COG5 PF10392.4 EGG11089.1 - 0.84 9.5 6.2 19 5.1 1.0 3.1 1 1 2 3 3 3 0 Golgi transport complex subunit 5 FH2 PF02181.18 EGG11089.1 - 1.2 7.9 10.7 1.5 7.5 2.7 2.7 1 1 2 3 3 3 0 Formin Homology 2 Domain SlyX PF04102.7 EGG11089.1 - 2 8.8 8.6 12 6.3 0.2 3.5 2 2 1 3 3 3 0 SlyX Apolipoprotein PF01442.13 EGG11089.1 - 2.8 7.3 12.7 7.4 6.0 8.8 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_p24 PF05073.7 EGG11089.1 - 3.1 7.3 7.1 0.89 9.0 1.5 2.2 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Cauli_DNA-bind PF03310.8 EGG11089.1 - 4.3 7.1 9.7 3.7 7.4 2.3 3.5 2 1 2 4 4 4 0 Caulimovirus DNA-binding protein Occludin_ELL PF07303.8 EGG11089.1 - 6.2 7.6 6.9 33 5.2 1.5 2.7 1 1 0 2 2 2 0 Occludin homology domain DUF972 PF06156.8 EGG11089.1 - 8 6.8 15.5 0.28 11.5 2.9 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Tcp11 PF05794.8 EGG11090.1 - 0.088 11.5 0.1 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 T-complex protein 11 Sad1_UNC PF07738.8 EGG11091.1 - 2.3e-30 105.1 0.0 3.3e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal WSC PF01822.14 EGG11093.1 - 0.022 14.6 5.4 0.061 13.2 3.8 1.8 1 0 0 1 1 1 0 WSC domain Acetyltransf_9 PF13527.1 EGG11094.1 - 0.0041 16.9 0.0 0.0097 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGG11094.1 - 0.083 12.7 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGG11094.1 - 0.12 12.5 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Muted PF14942.1 EGG11096.1 - 0.00079 19.3 7.1 0.0013 18.5 4.9 1.3 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein TFIIF_alpha PF05793.7 EGG11096.1 - 0.0023 16.3 36.5 0.003 16.0 25.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF572 PF04502.8 EGG11096.1 - 0.045 12.9 20.3 0.057 12.6 14.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DNA_pol_viral_N PF00242.12 EGG11096.1 - 0.077 12.0 18.4 0.1 11.6 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain BUD22 PF09073.5 EGG11096.1 - 0.085 11.9 35.9 0.11 11.4 24.9 1.1 1 0 0 1 1 1 0 BUD22 MIP-T3 PF10243.4 EGG11096.1 - 0.11 10.9 28.2 0.15 10.4 19.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1675 PF07897.6 EGG11096.1 - 0.12 12.2 16.7 0.14 12.0 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF2217 PF10265.4 EGG11096.1 - 0.14 10.8 14.0 0.17 10.6 9.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PBP_sp32 PF07222.7 EGG11096.1 - 0.14 11.2 7.0 0.3 10.2 4.9 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Menin PF05053.8 EGG11096.1 - 0.19 9.8 9.1 0.24 9.5 6.3 1.1 1 0 0 1 1 1 0 Menin PMSI1 PF15322.1 EGG11096.1 - 0.25 10.3 11.7 0.34 9.9 8.1 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Ndc1_Nup PF09531.5 EGG11096.1 - 1 7.7 14.3 1.2 7.4 9.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.4 EGG11096.1 - 1 7.5 23.6 1.4 7.1 16.3 1.1 1 0 0 1 1 1 0 Transmembrane protein GNT-I PF03071.10 EGG11096.1 - 1.8 7.0 6.6 2.6 6.4 4.6 1.1 1 0 0 1 1 1 0 GNT-I family Neur_chan_memb PF02932.11 EGG11096.1 - 2.3 8.0 8.3 3.1 7.6 5.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RabGAP-TBC PF00566.13 EGG11096.1 - 3.3 7.1 6.8 5.2 6.4 4.7 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain DUF2413 PF10310.4 EGG11096.1 - 3.7 6.2 21.8 4.6 5.9 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Atrophin-1 PF03154.10 EGG11096.1 - 5.9 4.8 29.3 7.5 4.5 20.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF1682 PF07946.9 EGG11096.1 - 8 5.2 19.7 11 4.7 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Rootletin PF15035.1 EGG11097.1 - 0.0011 18.9 8.7 0.0019 18.2 6.0 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Laminin_II PF06009.7 EGG11097.1 - 0.023 14.4 3.7 1.4 8.6 0.3 2.4 1 1 1 2 2 2 0 Laminin Domain II Fib_alpha PF08702.5 EGG11097.1 - 0.047 13.8 4.6 0.1 12.7 3.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_23 PF13476.1 EGG11097.1 - 0.075 13.3 1.3 0.095 13.0 0.9 1.3 1 0 0 1 1 1 0 AAA domain DUF2205 PF10224.4 EGG11097.1 - 0.093 12.3 5.8 0.66 9.5 0.1 2.8 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Imm6 PF14434.1 EGG11097.1 - 0.095 12.4 1.1 0.16 11.6 0.7 1.4 1 0 0 1 1 1 0 Immunity protein Imm6 Phage_GP20 PF06810.6 EGG11097.1 - 0.1 12.0 3.5 0.21 10.9 2.4 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF948 PF06103.6 EGG11097.1 - 0.25 11.2 1.0 0.62 9.9 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.3 EGG11097.1 - 0.66 9.8 13.3 0.035 13.9 4.8 2.1 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.7 EGG11097.1 - 0.86 10.0 5.5 1.5 9.2 1.4 2.5 1 1 1 2 2 2 0 SlyX DUF1664 PF07889.7 EGG11097.1 - 1.2 8.9 4.6 2.3 8.0 2.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF904 PF06005.7 EGG11098.1 - 0.02 15.1 5.4 0.035 14.3 0.5 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF904) Sec2p PF06428.6 EGG11099.1 - 0.027 14.3 0.2 0.097 12.5 0.0 1.9 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Peptidase_C97 PF05903.9 EGG11100.1 - 1.4e-21 76.8 0.0 1.5e-14 54.0 0.0 2.2 2 0 0 2 2 2 2 PPPDE putative peptidase domain ATG16 PF08614.6 EGG11100.1 - 0.011 15.5 0.2 0.015 15.0 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PAP1 PF08601.5 EGG11100.1 - 1.3 8.6 11.0 2 8.0 7.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Vac_ImportDeg PF09783.4 EGG11102.1 - 2.5e-29 102.0 4.0 2.7e-29 101.9 2.8 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF1442 PF07279.6 EGG11102.1 - 0.058 12.4 0.0 0.13 11.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1442) UPF0172 PF03665.8 EGG11102.1 - 0.12 11.8 0.1 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) DNA_pol_B PF00136.16 EGG11103.1 - 7.3e-90 301.9 0.0 1.1e-89 301.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGG11103.1 - 1.4e-16 60.2 0.0 2.8e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EGG11103.1 - 6.2e-10 38.9 2.2 1.2e-09 38.0 1.6 1.4 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Zn-ribbon_8 PF09723.5 EGG11106.1 - 0.021 14.7 5.7 0.31 11.0 1.0 3.3 3 0 0 3 3 3 0 Zinc ribbon domain Pkinase PF00069.20 EGG11108.1 - 1.2e-43 149.0 0.0 1.5e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11108.1 - 9.5e-26 90.4 0.0 1.1e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG11108.1 - 4.6e-07 29.0 0.0 6.4e-07 28.6 0.0 1.2 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGG11108.1 - 5.2e-05 23.0 0.0 0.0024 17.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGG11108.1 - 0.011 14.8 0.2 0.014 14.4 0.2 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WH1 PF00568.18 EGG11108.1 - 0.051 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 WH1 domain DUF1679 PF07914.6 EGG11108.1 - 0.094 11.3 0.1 1.9 7.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) RIO1 PF01163.17 EGG11108.1 - 0.12 11.7 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 RIO1 family TFIIA PF03153.8 EGG11109.1 - 0.1 12.4 5.3 0.13 12.1 3.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EGG11109.1 - 0.4 8.5 10.5 0.51 8.1 7.3 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EGG11109.1 - 0.86 8.8 9.4 1.2 8.3 6.5 1.3 1 0 0 1 1 1 0 SDA1 Spt5_N PF11942.3 EGG11109.1 - 3.2 8.4 28.2 0.39 11.3 4.6 2.5 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Prothymosin PF03247.9 EGG11109.1 - 9.7 6.3 27.5 6.4 6.9 6.0 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Pro_isomerase PF00160.16 EGG11110.1 - 1.8e-35 122.4 0.0 3.5e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EGG11110.1 - 8.7e-17 60.5 0.0 1.6e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG11110.1 - 1.1e-10 41.3 0.0 2.8e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG11110.1 - 3.1e-10 39.7 0.0 6.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3455 PF11937.3 EGG11111.1 - 1.9e-17 63.7 0.0 2.6e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Mitofilin PF09731.4 EGG11112.1 - 5.4e-117 391.8 3.6 6.4e-117 391.6 2.5 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF2384 PF09722.5 EGG11112.1 - 0.078 12.8 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) bZIP_1 PF00170.16 EGG11113.1 - 1.2e-06 28.3 7.9 1.9e-06 27.6 5.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGG11113.1 - 0.0058 16.4 11.8 0.0094 15.7 8.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Rad1 PF02144.11 EGG11114.1 - 1.5e-12 46.8 0.0 1.6e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF3989 PF13150.1 EGG11114.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) FTHFS PF01268.14 EGG11118.1 - 1.2e-259 862.0 0.1 1.2e-259 862.0 0.1 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EGG11118.1 - 1.9e-65 218.8 1.1 3.9e-65 217.8 0.3 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EGG11118.1 - 1.1e-31 109.2 0.2 4.5e-31 107.3 0.2 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Ecl1 PF12855.2 EGG11119.1 - 0.45 9.8 5.8 8.8 5.7 1.4 2.8 1 1 1 2 2 2 0 Life-span regulatory factor DUF1688 PF07958.6 EGG11120.1 - 5.5e-139 463.3 0.0 6.3e-139 463.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF2762 PF10960.3 EGG11121.1 - 0.09 12.5 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) FAD-SLDH PF12318.3 EGG11121.1 - 0.095 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Pro_isomerase PF00160.16 EGG11122.1 - 2e-45 154.7 0.2 3e-45 154.1 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EGG11122.1 - 3e-08 33.1 1.2 0.00037 20.0 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGG11122.1 - 0.0015 18.0 1.7 0.0054 16.2 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGG11122.1 - 0.023 14.5 3.9 15 5.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGG11122.1 - 0.29 10.9 7.8 12 5.9 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 EGG11123.1 - 4.2e-09 36.0 4.2 8.4e-09 35.1 2.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGG11123.1 - 0.00031 20.4 2.9 0.00067 19.3 2.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGG11123.1 - 0.001 18.6 2.2 0.0024 17.5 1.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG11123.1 - 0.0056 16.6 5.6 0.0056 16.6 3.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG11123.1 - 0.23 11.1 3.3 0.96 9.1 2.3 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGG11123.1 - 0.62 9.6 4.0 1.2 8.7 2.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.1 EGG11123.1 - 4.2 7.8 5.6 0.99 9.8 1.3 2.0 2 0 0 2 2 2 0 Zinc-finger double domain VWA_2 PF13519.1 EGG11124.1 - 3.3e-11 43.6 0.1 5.2e-11 42.9 0.0 1.5 1 1 1 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 EGG11124.1 - 8.8e-10 37.3 13.4 0.0053 16.2 0.3 4.0 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.9 EGG11124.1 - 0.00038 20.1 0.7 0.0012 18.5 0.0 1.9 2 0 0 2 2 2 1 Ssl1-like MIS13 PF08202.6 EGG11129.1 - 0.017 14.1 0.2 0.041 12.9 0.0 1.6 2 0 0 2 2 2 0 Mis12-Mtw1 protein family RINGv PF12906.2 EGG11131.1 - 0.068 13.2 0.2 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 RING-variant domain DUF2236 PF09995.4 EGG11132.1 - 1.2e-13 50.9 0.0 1.7e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) zf-RING_2 PF13639.1 EGG11133.1 - 0.0013 18.4 2.9 0.0024 17.6 2.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGG11133.1 - 0.29 10.8 3.4 0.54 10.0 2.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Cation_efflux PF01545.16 EGG11134.1 - 4.6e-29 101.3 2.2 5.3e-29 101.1 1.6 1.0 1 0 0 1 1 1 1 Cation efflux family Abhydro_lipase PF04083.11 EGG11136.1 - 6e-15 54.3 0.1 1.2e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EGG11136.1 - 1e-06 28.8 1.3 1.9e-06 27.9 0.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG11136.1 - 0.00067 19.4 0.0 0.0012 18.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG11136.1 - 0.027 14.0 1.1 0.19 11.2 0.3 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold Jun PF03957.8 EGG11137.1 - 0.0065 16.2 1.1 0.013 15.2 0.8 1.4 1 0 0 1 1 1 1 Jun-like transcription factor Ten1_2 PF15490.1 EGG11138.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit DUF605 PF04652.11 EGG11141.1 - 0.69 9.2 22.7 0.86 8.9 15.7 1.1 1 0 0 1 1 1 0 Vta1 like Ndc1_Nup PF09531.5 EGG11141.1 - 7.4 4.8 9.1 8.9 4.5 6.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3704 PF12488.3 EGG11143.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) Fer4_17 PF13534.1 EGG11143.1 - 0.37 11.1 4.1 0.99 9.8 2.8 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF678 PF05077.7 EGG11143.1 - 0.5 10.3 4.8 1.1 9.3 1.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF678) Exo_endo_phos_2 PF14529.1 EGG11145.1 - 0.1 12.2 0.1 0.2 11.2 0.1 1.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase V-ATPase_G PF03179.10 EGG11146.1 - 0.0048 17.1 0.5 0.0084 16.3 0.4 1.4 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit PAM2 PF07145.10 EGG11146.1 - 0.23 11.0 1.4 0.45 10.1 1.0 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Spectrin PF00435.16 EGG11147.1 - 0.024 14.9 2.4 0.062 13.5 1.7 1.8 1 1 0 1 1 1 0 Spectrin repeat DUF4363 PF14276.1 EGG11147.1 - 0.24 11.1 1.1 1.4 8.6 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) PRP1_N PF06424.7 EGG11149.1 - 0.068 13.4 9.4 0.087 13.1 6.5 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Cyclin PF08613.6 EGG11150.1 - 4.2e-14 53.2 0.0 7e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EGG11150.1 - 1.2e-12 47.5 0.1 1.8e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain RVT_3 PF13456.1 EGG11151.1 - 5.6e-07 29.2 0.1 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like PRCH PF03967.8 EGG11152.1 - 0.27 10.8 0.3 0.68 9.5 0.2 1.6 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region Abhydrolase_3 PF07859.8 EGG11153.1 - 3.5e-41 141.0 0.0 2.1e-32 112.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EGG11153.1 - 2.5e-14 52.7 0.0 5.1e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EGG11153.1 - 0.0018 17.0 0.0 0.013 14.2 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family RRM_6 PF14259.1 EGG11156.1 - 8e-14 51.3 0.2 3.1e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG11156.1 - 8.6e-11 41.5 0.1 4.2e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGG11156.1 - 1e-09 37.8 0.7 0.00015 21.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGG11156.1 - 2.3e-08 33.6 0.0 0.00028 20.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EGG11156.1 - 4.2e-05 23.0 5.1 7.6e-05 22.2 3.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 EGG11156.1 - 0.086 12.7 4.4 4.4 7.2 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif ELO PF01151.13 EGG11158.1 - 1.4e-29 103.1 3.7 1.6e-29 102.9 2.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4079 PF13301.1 EGG11158.1 - 0.0073 16.3 0.7 0.01 15.8 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) ATP-synt_Eps PF04627.8 EGG11159.1 - 1.7e-14 53.0 2.2 2.4e-14 52.6 1.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Trigger_C PF05698.9 EGG11159.1 - 0.052 13.3 0.1 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus NAD_binding_6 PF08030.7 EGG11161.1 - 3.3e-35 121.2 0.0 1.2e-34 119.5 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGG11161.1 - 5.2e-21 74.4 0.1 1.1e-20 73.4 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGG11161.1 - 5.8e-15 55.4 10.5 5.8e-15 55.4 7.3 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGG11161.1 - 0.0014 18.7 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGG11161.1 - 0.075 13.6 0.0 0.47 11.0 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain PP2C PF00481.16 EGG11162.1 - 3.3e-36 124.9 0.0 1.4e-33 116.3 0.0 2.4 2 1 0 3 3 3 2 Protein phosphatase 2C UBN2_3 PF14244.1 EGG11163.1 - 0.00011 21.8 0.7 0.0023 17.4 0.4 2.2 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGG11163.1 - 0.0013 18.5 0.2 0.0021 17.8 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG11163.1 - 0.0037 16.8 0.1 0.0068 15.9 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HTH_19 PF12844.2 EGG11163.1 - 0.12 12.4 1.2 0.21 11.6 0.1 1.9 3 0 0 3 3 3 0 Helix-turn-helix domain MpPF26 PF07666.6 EGG11166.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 ESSS PF10183.4 EGG11169.1 - 4e-24 85.0 0.3 5.9e-24 84.4 0.2 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Lipoprotein_19 PF13617.1 EGG11169.1 - 0.053 13.1 0.6 0.086 12.4 0.4 1.4 1 0 0 1 1 1 0 YnbE-like lipoprotein Baculo_PEP_C PF04513.7 EGG11170.1 - 0.039 13.7 0.9 0.081 12.7 0.6 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Herpes_U44 PF04533.8 EGG11175.1 - 0.029 13.6 1.0 0.041 13.1 0.7 1.2 1 0 0 1 1 1 0 Herpes virus U44 protein SATase_N PF06426.9 EGG11175.1 - 0.045 13.9 0.1 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal DUF2413 PF10310.4 EGG11175.1 - 1.1 7.9 9.0 1.6 7.5 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RNR_inhib PF08591.5 EGG11179.1 - 0.034 15.0 0.1 0.041 14.7 0.0 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase inhibitor DUF3919 PF13057.1 EGG11181.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) DUF4041 PF13250.1 EGG11182.1 - 0.0013 18.2 0.4 0.88 9.1 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4041) PerC PF06069.6 EGG11182.1 - 0.0072 16.3 0.6 3.4 7.7 0.0 3.3 4 0 0 4 4 4 2 PerC transcriptional activator PurS PF02700.9 EGG11182.1 - 0.087 12.7 0.2 1 9.3 0.0 2.9 2 1 0 2 2 2 0 Phosphoribosylformylglycinamidine (FGAM) synthase PTPS PF01242.14 EGG11182.1 - 0.14 11.8 0.0 11 5.7 0.0 3.0 3 0 0 3 3 3 0 6-pyruvoyl tetrahydropterin synthase Asp PF00026.18 EGG11183.1 - 2.1e-52 178.3 0.3 2.1e-28 99.4 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG11183.1 - 7.2e-08 32.5 0.0 5.5e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EGG11183.1 - 0.1 12.1 0.0 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal SMC_N PF02463.14 EGG11185.1 - 1.9e-67 226.7 0.0 8.1e-66 221.4 0.0 3.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGG11185.1 - 3.3e-22 78.7 0.2 1.3e-21 76.8 0.1 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGG11185.1 - 1.5e-12 48.0 4.2 1.2e-05 25.4 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EGG11185.1 - 3.7e-11 43.7 25.4 3.7e-11 43.7 17.6 5.1 2 2 2 4 4 2 1 AAA domain AAA_29 PF13555.1 EGG11185.1 - 6.8e-05 22.3 0.1 0.00019 20.9 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain WEMBL PF05701.6 EGG11185.1 - 7.6e-05 21.3 26.3 7.6e-05 21.3 18.2 3.8 2 2 1 3 3 2 1 Weak chloroplast movement under blue light AAA_13 PF13166.1 EGG11185.1 - 0.00014 20.4 15.0 0.00014 20.4 10.4 5.1 4 1 0 5 5 5 1 AAA domain Filament PF00038.16 EGG11185.1 - 0.0034 16.8 4.2 0.0034 16.8 2.9 5.5 3 2 2 5 5 5 2 Intermediate filament protein DUF4164 PF13747.1 EGG11185.1 - 0.004 17.2 5.5 0.004 17.2 3.8 7.2 5 3 2 7 7 7 2 Domain of unknown function (DUF4164) Reo_sigmaC PF04582.7 EGG11185.1 - 0.1 11.7 24.5 0.46 9.6 2.6 5.1 4 2 2 6 6 6 0 Reovirus sigma C capsid protein EzrA PF06160.7 EGG11185.1 - 3.4 5.7 60.8 0.78 7.8 7.2 5.9 2 2 3 5 5 5 0 Septation ring formation regulator, EzrA CBFD_NFYB_HMF PF00808.18 EGG11186.1 - 1.8e-14 53.5 0.4 3e-14 52.8 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGG11186.1 - 0.0081 16.2 0.7 0.012 15.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 EGG11186.1 - 0.069 13.4 0.3 1.7 8.9 0.0 2.2 1 1 0 2 2 2 0 Transcription initiation factor TFIID subunit A rve PF00665.21 EGG11186.1 - 0.12 12.4 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain Sugar_tr PF00083.19 EGG11192.1 - 1.5e-86 290.7 17.1 1.8e-86 290.5 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG11192.1 - 2e-23 82.6 34.6 2.6e-23 82.2 15.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Redoxin PF08534.5 EGG11195.1 - 1.4e-19 70.0 0.0 1.7e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin Cobl PF09469.5 EGG11196.1 - 4.5 7.3 6.4 11 6.0 1.6 3.1 1 1 1 2 2 2 0 Cordon-bleu ubiquitin-like domain PI3_PI4_kinase PF00454.22 EGG11197.1 - 8.7e-31 107.1 0.1 1.8e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EGG11197.1 - 4.8e-08 32.3 0.2 2.3e-07 30.1 0.1 2.0 1 1 1 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pik1 PF11522.3 EGG11197.1 - 0.00013 21.6 1.4 0.0013 18.4 0.1 2.9 2 1 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Gly-zipper_OmpA PF13436.1 EGG11197.1 - 0.17 11.5 2.6 0.39 10.3 1.8 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain KxDL PF10241.4 EGG11199.1 - 0.029 14.2 0.4 0.037 13.9 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein Mito_fiss_reg PF05308.6 EGG11199.1 - 0.032 13.6 0.1 0.036 13.4 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator PEP-utilisers_N PF05524.8 EGG11199.1 - 0.073 12.8 0.2 0.079 12.7 0.1 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal IncA PF04156.9 EGG11200.1 - 3.6 7.1 6.5 6.3 6.3 4.5 1.3 1 0 0 1 1 1 0 IncA protein CcdB PF01845.12 EGG11201.1 - 0.072 13.0 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 CcdB protein Pol_alpha_B_N PF08418.5 EGG11201.1 - 0.096 12.2 6.4 0.1 12.1 4.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal p450 PF00067.17 EGG11203.1 - 2.4e-68 230.7 0.0 3.1e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PsaM PF07465.8 EGG11205.1 - 4.4 6.9 6.6 1.9 8.1 2.8 1.6 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) bZIP_1 PF00170.16 EGG11206.1 - 1.2e-06 28.3 11.2 2.5e-06 27.3 7.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor CENP-Q PF13094.1 EGG11206.1 - 0.0012 18.8 4.7 0.0012 18.8 3.2 2.3 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Taxilin PF09728.4 EGG11206.1 - 0.0029 16.7 3.7 0.0052 15.9 2.5 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein bZIP_2 PF07716.10 EGG11206.1 - 0.0063 16.3 11.0 0.014 15.2 7.6 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Med4 PF10018.4 EGG11207.1 - 6.4e-16 58.3 1.8 6.6e-16 58.2 0.1 1.8 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Gal-3-0_sulfotr PF06990.6 EGG11207.1 - 0.026 13.2 0.1 0.06 11.9 0.0 1.5 1 1 0 1 1 1 0 Galactose-3-O-sulfotransferase Nab2 PF11517.3 EGG11207.1 - 0.052 13.6 0.3 0.14 12.2 0.1 1.7 1 1 1 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) H-kinase_dim PF02895.9 EGG11207.1 - 0.086 13.1 3.0 2.7 8.3 0.2 2.6 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Exonuc_VII_L PF02601.10 EGG11207.1 - 1.1 8.3 7.9 1.5 7.9 5.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Luteo_Vpg PF01659.11 EGG11207.1 - 1.2 8.8 8.5 0.84 9.3 0.6 2.8 3 0 0 3 3 3 0 Luteovirus putative VPg genome linked protein Telethonin PF09470.5 EGG11208.1 - 0.093 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Telethonin protein DUF4127 PF13552.1 EGG11209.1 - 0.1 10.9 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) p450 PF00067.17 EGG11211.1 - 9.4e-11 40.8 0.0 2.1e-06 26.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Cytochrom_B561 PF03188.11 EGG11212.1 - 5.7e-14 52.1 5.8 5.7e-14 52.1 4.0 1.8 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 PepSY_TM_2 PF13703.1 EGG11212.1 - 0.56 10.4 12.3 0.14 12.3 2.8 3.1 1 1 1 2 2 2 0 PepSY-associated TM helix Cytochrom_B_N PF00033.14 EGG11212.1 - 1.1 8.5 11.5 0.12 11.7 2.1 2.3 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Ferric_reduct PF01794.14 EGG11212.1 - 1.8 8.6 10.0 0.87 9.6 1.1 2.5 1 1 1 2 2 2 0 Ferric reductase like transmembrane component DUF2306 PF10067.4 EGG11212.1 - 2.4 8.3 14.3 2 8.6 0.4 3.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) DUF2231 PF09990.4 EGG11212.1 - 8.5 6.7 9.2 5.8 7.3 2.2 2.6 1 1 2 3 3 3 0 Predicted membrane protein (DUF2231) NAD_Gly3P_dh_N PF01210.18 EGG11215.1 - 0.049 13.3 0.7 9.8 5.8 0.0 3.1 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Colipase-like PF15083.1 EGG11215.1 - 0.072 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Colipase-like PhyH PF05721.8 EGG11216.1 - 1.2e-48 165.9 0.0 1.5e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pol_alpha_B_N PF08418.5 EGG11217.1 - 0.016 14.7 3.1 0.022 14.3 2.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Glyco_transf_90 PF05686.7 EGG11221.1 - 3.5e-16 58.8 1.7 1.3e-15 57.0 0.4 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 90 Tetraspannin PF00335.15 EGG11221.1 - 0.035 13.3 1.5 0.06 12.6 1.0 1.3 1 0 0 1 1 1 0 Tetraspanin family ABC_ATPase PF09818.4 EGG11222.1 - 0.12 10.9 0.1 0.42 9.1 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF3134 PF11332.3 EGG11225.1 - 0.89 9.7 6.2 17 5.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) zf-H2C2_2 PF13465.1 EGG11226.1 - 1.4e-06 28.2 20.3 0.00034 20.7 3.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGG11226.1 - 1.7e-06 27.9 13.1 0.0036 17.5 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGG11226.1 - 1.8e-06 27.9 19.8 9.2e-06 25.7 0.7 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EGG11226.1 - 0.00051 19.8 4.6 0.015 15.2 0.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 EGG11226.1 - 0.0041 17.2 0.3 0.0041 17.2 0.2 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EGG11226.1 - 0.2 11.7 5.1 0.39 10.8 3.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EGG11226.1 - 0.2 11.7 5.5 4.1 7.5 0.1 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EGG11226.1 - 0.92 9.2 6.7 13 5.5 0.0 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type RAP1 PF07218.6 EGG11226.1 - 2.3 6.1 5.4 3.1 5.7 3.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-C2H2_jaz PF12171.3 EGG11226.1 - 6.3 7.0 6.7 4.4 7.5 0.0 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EGG11226.1 - 8.3 6.2 9.9 8.6 6.2 2.3 3.1 1 1 1 2 2 2 0 BED zinc finger Apc15p PF05841.6 EGG11227.1 - 0.00017 22.2 1.5 0.0002 22.0 0.3 1.7 2 0 0 2 2 2 1 Apc15p protein Mem_trans PF03547.13 EGG11228.1 - 5.1e-25 87.5 0.2 9e-25 86.7 0.1 1.3 1 1 0 1 1 1 1 Membrane transport protein zf-H2C2_2 PF13465.1 EGG11229.1 - 1.1e-05 25.4 4.5 1.1e-05 25.4 3.1 2.0 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGG11229.1 - 2.9e-05 24.1 13.2 0.00018 21.6 4.5 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG11229.1 - 4.8e-05 23.4 11.6 0.00017 21.6 5.6 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger DUF629 PF04780.7 EGG11229.1 - 0.02 13.4 1.5 0.019 13.5 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 EGG11229.1 - 0.028 14.5 1.9 0.03 14.4 1.3 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EGG11229.1 - 0.077 12.9 3.7 0.079 12.8 0.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGG11229.1 - 0.73 10.0 6.6 0.51 10.5 1.4 2.2 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EGG11229.1 - 2.2 8.6 11.8 9.4 6.6 5.1 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Ofd1_CTDD PF10637.4 EGG11230.1 - 1.1e-83 280.4 0.6 4.6e-76 255.4 0.1 2.6 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EGG11230.1 - 3.4e-17 62.7 0.1 1e-16 61.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PH PF00169.24 EGG11230.1 - 0.014 15.5 0.6 0.12 12.5 0.1 2.5 2 0 0 2 2 2 0 PH domain 2OG-FeII_Oxy_4 PF13661.1 EGG11230.1 - 0.05 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily B3_4 PF03483.12 EGG11232.1 - 8.4e-23 80.7 0.2 1.4e-22 80.0 0.2 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EGG11232.1 - 1.9e-18 66.0 0.0 1e-14 54.1 0.0 2.8 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 EGG11232.1 - 0.013 14.7 0.0 0.079 12.1 0.0 2.0 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) Grp1_Fun34_YaaH PF01184.14 EGG11233.1 - 8.7e-79 263.6 19.0 1.1e-78 263.4 13.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family WD40 PF00400.27 EGG11234.1 - 1.3e-45 151.7 23.5 5e-08 32.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat OTU PF02338.14 EGG11235.1 - 0.00035 21.1 0.0 0.00065 20.2 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGG11235.1 - 0.011 15.1 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase C65 Otubain WD40 PF00400.27 EGG11238.1 - 8.4e-40 133.2 17.1 2.1e-08 33.7 0.4 9.1 9 0 0 9 9 9 6 WD domain, G-beta repeat Hira PF07569.6 EGG11238.1 - 2e-25 89.2 3.3 7.5e-22 77.6 0.1 2.5 1 1 1 2 2 2 2 TUP1-like enhancer of split HIRA_B PF09453.5 EGG11238.1 - 9.1e-06 25.0 2.1 9.5e-06 25.0 0.0 2.1 2 0 0 2 2 2 1 HIRA B motif Neuregulin PF02158.10 EGG11242.1 - 0.0086 14.9 0.9 0.0086 14.9 0.6 1.4 1 1 0 1 1 1 1 Neuregulin family FAM104 PF15434.1 EGG11242.1 - 0.32 11.2 5.2 1.4 9.1 0.1 2.2 2 0 0 2 2 2 0 Family 104 Metallophos PF00149.23 EGG11243.1 - 1.3e-41 142.1 0.4 1.9e-41 141.6 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 2-Hacid_dh_C PF02826.14 EGG11246.1 - 1.9e-50 170.4 0.0 5.7e-50 168.9 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGG11246.1 - 3.5e-28 97.6 0.0 4.5e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGG11246.1 - 0.0036 17.1 0.2 0.008 16.0 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EGG11246.1 - 0.0046 16.8 0.0 0.0095 15.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ribosomal_60s PF00428.14 EGG11247.1 - 4.3e-27 94.3 6.0 5.2e-27 94.0 4.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein LEA_6 PF10714.4 EGG11247.1 - 0.46 10.3 4.7 0.73 9.6 3.2 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 zf-RING_2 PF13639.1 EGG11249.1 - 6.2e-08 32.3 0.5 6.2e-08 32.3 0.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGG11249.1 - 0.026 14.5 0.9 0.026 14.5 0.6 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGG11249.1 - 1.8 8.3 6.4 0.14 11.8 0.6 2.0 2 0 0 2 2 2 0 zinc-RING finger domain WW PF00397.21 EGG11250.1 - 2.4e-09 36.9 0.0 4.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 WW domain FAD_binding_4 PF01565.18 EGG11251.1 - 4e-26 91.1 0.2 7.1e-26 90.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGG11251.1 - 2.7e-12 46.3 2.4 5.9e-12 45.3 1.6 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EGG11251.1 - 0.0015 17.7 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding MBOAT_2 PF13813.1 EGG11253.1 - 1e-14 54.3 2.1 3.5e-14 52.6 1.5 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Nramp PF01566.13 EGG11254.1 - 5e-90 301.8 9.4 2.2e-50 171.4 0.4 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein ODV-E18 PF10717.4 EGG11254.1 - 0.57 9.6 4.1 0.25 10.7 0.5 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF2976 PF11190.3 EGG11254.1 - 2.3 7.7 8.1 0.1 12.1 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) AA_kinase PF00696.23 EGG11255.1 - 3.5e-30 105.3 0.0 2.3e-28 99.3 0.0 2.2 2 0 0 2 2 2 2 Amino acid kinase family ACT PF01842.20 EGG11255.1 - 2.2e-11 42.9 0.1 4.8e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EGG11255.1 - 1.5e-09 37.2 3.2 1.9e-07 30.5 0.2 2.4 2 0 0 2 2 2 2 ACT domain ADH_N PF08240.7 EGG11257.1 - 1.5e-33 114.8 2.6 3.1e-33 113.7 1.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGG11257.1 - 2.4e-16 59.4 0.0 4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EGG11257.1 - 7.1e-06 25.2 0.1 1.1e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N_2 PF13602.1 EGG11257.1 - 0.00016 22.5 0.0 0.00031 21.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EGG11257.1 - 0.0097 16.1 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EGG11257.1 - 0.015 15.4 0.1 0.032 14.3 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EGG11257.1 - 0.03 12.7 0.3 0.042 12.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.1 EGG11257.1 - 0.037 14.0 0.1 0.083 12.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGG11257.1 - 0.047 14.0 0.1 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EGG11257.1 - 0.075 12.8 0.5 0.23 11.2 0.3 1.8 1 1 1 2 2 2 0 ThiF family Methyltransf_24 PF13578.1 EGG11257.1 - 0.12 13.2 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2338 PF10100.4 EGG11257.1 - 0.16 10.2 0.0 0.22 9.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) NAD_binding_9 PF13454.1 EGG11257.1 - 0.18 11.6 0.5 4.1 7.1 0.1 2.2 1 1 1 2 2 2 0 FAD-NAD(P)-binding MBOAT_2 PF13813.1 EGG11258.1 - 1.7e-05 24.8 0.8 8.6e-05 22.5 0.5 2.2 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family DUF3720 PF12517.3 EGG11258.1 - 0.079 13.6 2.8 0.11 13.2 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) Coatomer_E PF04733.9 EGG11259.1 - 1.6e-23 83.3 0.3 2.7e-23 82.6 0.2 1.2 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EGG11259.1 - 0.00012 22.3 0.5 0.79 10.1 0.0 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGG11259.1 - 0.0014 19.0 0.1 2.9 8.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGG11259.1 - 0.099 12.6 0.0 0.51 10.3 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat POLO_box PF00659.13 EGG11264.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 POLO box duplicated region F-box-like PF12937.2 EGG11271.1 - 0.00012 21.6 0.1 0.0004 20.0 0.1 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EGG11271.1 - 0.0034 16.9 0.2 0.014 15.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 EGG11271.1 - 0.016 14.9 1.0 0.042 13.6 0.7 1.8 1 0 0 1 1 1 0 Leucine rich repeat LRR_4 PF12799.2 EGG11271.1 - 0.038 13.6 0.4 0.038 13.6 0.3 2.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) IPK PF03770.11 EGG11272.1 - 1.7e-37 128.9 0.1 1.9e-37 128.8 0.1 1.0 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF2390 PF09523.5 EGG11273.1 - 0.33 11.1 6.5 0.2 11.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Peroxin-22 PF12827.2 EGG11274.1 - 0.037 13.7 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family ACOX PF01756.14 EGG11275.1 - 7.8e-39 132.9 0.0 1.4e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EGG11275.1 - 1.3e-26 93.3 1.9 2.5e-26 92.3 1.3 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EGG11275.1 - 7.3e-14 51.0 0.0 1.9e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EGG11275.1 - 0.00017 21.7 2.6 0.0013 18.8 1.8 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain COPIIcoated_ERV PF07970.7 EGG11276.1 - 1.1e-37 129.8 0.1 1.8e-37 129.1 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGG11276.1 - 6.2e-25 87.0 0.0 1e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Nfu_N PF08712.6 EGG11278.1 - 1.3e-30 104.8 0.0 3.5e-30 103.4 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EGG11278.1 - 5.3e-21 74.1 0.1 9.5e-21 73.3 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain CtIP_N PF10482.4 EGG11278.1 - 0.1 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain MFS_1 PF07690.11 EGG11280.1 - 5e-34 117.5 20.3 1.8e-32 112.4 15.2 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily YtpI PF14007.1 EGG11280.1 - 0.0048 16.7 6.8 0.0089 15.9 0.8 3.5 3 0 0 3 3 3 1 YtpI-like protein NinB PF05772.7 EGG11280.1 - 0.03 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 NinB protein DUF3792 PF12670.2 EGG11280.1 - 1.4 8.7 26.3 0.38 10.6 5.5 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3792) NfeD PF01957.13 EGG11280.1 - 2.4 8.3 15.5 2.4 8.2 0.0 4.6 2 2 3 5 5 5 0 NfeD-like C-terminal, partner-binding bZIP_1 PF00170.16 EGG11282.1 - 1.5e-08 34.4 6.3 2.7e-08 33.6 4.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGG11282.1 - 3.8e-07 29.8 7.1 8.3e-07 28.7 4.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EGG11282.1 - 0.026 14.7 2.8 0.026 14.7 1.9 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Glyco_hydro_88 PF07470.8 EGG11283.1 - 1.3e-16 60.5 0.3 2.8e-16 59.4 0.1 1.5 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Glyco_hydro_88 PF07470.8 EGG11285.1 - 1.1e-12 47.7 0.1 1.4e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 LZ_Tnp_IS66 PF13007.2 EGG11286.1 - 0.018 15.6 0.3 0.026 15.1 0.2 1.4 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain FAM74 PF15026.1 EGG11286.1 - 0.14 11.7 0.4 0.18 11.4 0.3 1.3 1 1 0 1 1 1 0 FAM74 protein adh_short PF00106.20 EGG11288.1 - 1.7e-26 93.1 0.4 2.2e-25 89.5 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG11288.1 - 4.3e-12 46.0 0.2 9.4e-10 38.4 0.2 2.4 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 EGG11288.1 - 1.4e-08 34.7 0.0 2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGG11288.1 - 0.0023 17.4 0.1 0.005 16.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGG11288.1 - 0.022 13.6 0.0 0.053 12.3 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain SKIP_SNW PF02731.10 EGG11289.1 - 1.6e-65 219.3 0.9 1.6e-65 219.3 0.6 2.4 2 0 0 2 2 2 1 SKIP/SNW domain DUF4551 PF15087.1 EGG11290.1 - 4.2 5.6 8.0 0.8 7.9 3.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4551) LHC PF00556.15 EGG11291.1 - 4.4 7.2 5.6 0.68 9.8 1.2 1.7 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DUF177 PF02620.12 EGG11295.1 - 0.0094 15.9 0.2 0.016 15.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1399 Podoplanin PF05808.6 EGG11295.1 - 1.6 8.2 7.6 1.7 8.2 4.6 1.5 1 1 0 1 1 1 0 Podoplanin Tom22 PF04281.8 EGG11299.1 - 0.072 12.6 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Colicin_M PF14859.1 EGG11300.1 - 0.13 11.1 0.0 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Colicin M ZapA PF05164.8 EGG11301.1 - 0.22 11.4 1.9 0.58 10.1 1.3 1.7 1 0 0 1 1 1 0 Cell division protein ZapA Ribosomal_L17 PF01196.14 EGG11303.1 - 2.4e-29 101.7 0.6 6.5e-29 100.3 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L17 TFIIA PF03153.8 EGG11304.1 - 0.0081 16.0 9.6 0.0081 16.0 6.7 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 EGG11304.1 - 0.48 9.7 12.6 0.93 8.8 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 EGG11304.1 - 2 7.8 22.2 4 6.9 15.4 1.4 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.9 EGG11304.1 - 3.5 7.0 14.6 0.41 10.1 4.6 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Sporozoite_P67 PF05642.6 EGG11307.1 - 0.16 9.8 0.1 0.2 9.5 0.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen p450 PF00067.17 EGG11309.1 - 1.5e-51 175.4 0.0 2.1e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF746 PF05344.6 EGG11309.1 - 0.067 12.7 0.6 6.4 6.3 0.0 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF746) Beta_helix PF13229.1 EGG11310.1 - 1.1e-09 38.2 14.8 3.4e-09 36.6 10.3 1.8 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 EGG11310.1 - 1.9e-05 23.9 4.2 0.00095 18.3 2.9 2.2 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Peptidase_M22 PF00814.20 EGG11311.1 - 6.4e-80 268.4 0.0 7.8e-80 268.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family PA28_beta PF02252.13 EGG11312.1 - 3.3e-39 133.7 0.1 3.6e-39 133.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit DUF3220 PF11516.3 EGG11312.1 - 0.12 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) F-box-like PF12937.2 EGG11313.1 - 0.0075 15.9 1.4 0.0075 15.9 1.0 2.3 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EGG11313.1 - 0.022 14.3 5.2 0.38 10.4 0.4 3.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Alpha_kinase PF02816.13 EGG11316.1 - 2.7e-06 27.1 0.1 5e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Alpha-kinase family Membralin PF09746.4 EGG11316.1 - 0.07 12.1 0.4 0.15 11.0 0.1 1.6 2 0 0 2 2 2 0 Tumour-associated protein SpoIISA_toxin PF14171.1 EGG11320.1 - 0.075 12.2 0.1 0.094 11.9 0.1 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system HAP1_N PF04849.8 EGG11321.1 - 0.00075 18.5 1.5 0.0011 18.0 1.0 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF2937 PF11157.3 EGG11321.1 - 0.089 12.1 0.2 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) bZIP_1 PF00170.16 EGG11321.1 - 0.1 12.5 1.0 0.16 11.9 0.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.13 EGG11321.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family TMCO5 PF14992.1 EGG11321.1 - 0.1 11.6 1.0 0.14 11.2 0.7 1.1 1 0 0 1 1 1 0 TMCO5 family DivIC PF04977.10 EGG11321.1 - 0.31 10.5 1.3 0.47 9.9 0.9 1.2 1 0 0 1 1 1 0 Septum formation initiator TLC PF03219.9 EGG11323.1 - 0.027 12.9 0.0 0.032 12.7 0.0 1.1 1 0 0 1 1 1 0 TLC ATP/ADP transporter FAR1 PF03101.10 EGG11324.1 - 0.0096 16.4 0.6 0.026 15.0 0.4 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain Nucleoplasmin PF03066.10 EGG11325.1 - 0.47 9.9 13.0 0.64 9.5 9.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EGG11325.1 - 1.4 8.0 4.1 1.8 7.7 2.9 1.2 1 0 0 1 1 1 0 NOA36 protein VID27 PF08553.5 EGG11325.1 - 1.5 6.9 7.7 1.9 6.6 5.3 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Alpha_kinase PF02816.13 EGG11326.1 - 7.4e-12 45.3 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family Reo_sigmaC PF04582.7 EGG11328.1 - 0.0081 15.3 0.1 0.0087 15.2 0.1 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DivIC PF04977.10 EGG11328.1 - 0.021 14.3 1.4 2.7 7.5 0.1 2.4 1 1 1 2 2 2 0 Septum formation initiator FliJ PF02050.11 EGG11328.1 - 0.024 14.7 0.2 0.03 14.3 0.1 1.3 1 1 0 1 1 1 0 Flagellar FliJ protein Cast PF10174.4 EGG11328.1 - 0.028 12.5 0.7 0.028 12.4 0.5 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone CALCOCO1 PF07888.6 EGG11328.1 - 0.03 12.6 2.8 0.037 12.3 1.9 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.16 EGG11328.1 - 0.033 13.6 0.8 0.1 12.0 0.5 1.6 1 1 0 1 1 1 0 Intermediate filament protein HalX PF08663.5 EGG11328.1 - 0.036 14.0 1.3 0.046 13.7 0.1 1.6 2 0 0 2 2 2 0 HalX domain TMF_DNA_bd PF12329.3 EGG11328.1 - 0.042 13.6 0.5 6.5 6.6 0.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WEMBL PF05701.6 EGG11328.1 - 0.042 12.3 2.2 0.058 11.8 1.5 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF342 PF03961.8 EGG11328.1 - 0.074 11.4 0.2 0.082 11.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Med9 PF07544.8 EGG11328.1 - 0.077 12.7 0.5 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Spc24 PF08286.6 EGG11328.1 - 0.11 12.2 1.3 11 5.7 0.1 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fmp27_WPPW PF10359.4 EGG11328.1 - 0.11 10.8 0.9 0.12 10.7 0.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4618 PF15397.1 EGG11328.1 - 0.11 11.7 1.1 2.9 7.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) HR1 PF02185.11 EGG11328.1 - 0.12 12.1 0.3 0.37 10.5 0.1 1.8 1 1 0 1 1 1 0 Hr1 repeat Lzipper-MIP1 PF14389.1 EGG11328.1 - 0.12 12.4 1.1 1.1 9.4 0.1 2.3 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FlaC_arch PF05377.6 EGG11328.1 - 0.12 12.2 0.4 8.9 6.2 0.0 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) RasGAP_C PF03836.10 EGG11328.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.5 1 1 0 1 1 1 0 RasGAP C-terminus TBPIP PF07106.8 EGG11328.1 - 0.15 11.6 0.4 0.24 10.9 0.2 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 EGG11328.1 - 0.17 12.3 3.4 3.5 8.1 0.1 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) bZIP_2 PF07716.10 EGG11328.1 - 0.22 11.3 1.8 0.67 9.8 0.4 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF4164 PF13747.1 EGG11328.1 - 1.1 9.4 4.1 0.71 10.0 0.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF4200 PF13863.1 EGG11328.1 - 2.4 8.1 6.0 10 6.0 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Uds1 PF15456.1 EGG11329.1 - 0.0043 17.0 0.2 0.0053 16.7 0.1 1.2 1 0 0 1 1 1 1 Up-regulated During Septation DUF4218 PF13960.1 EGG11330.1 - 0.0015 18.0 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF3245 PF11595.3 EGG11330.1 - 0.014 15.6 3.1 0.038 14.2 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) K167R PF08065.7 EGG11332.1 - 0.23 11.5 1.4 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 K167R (NUC007) repeat GRIN_C PF15235.1 EGG11332.1 - 0.3 11.1 3.6 0.39 10.7 2.5 1.3 1 0 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus Sad1_UNC PF07738.8 EGG11333.1 - 6.7e-28 97.1 0.0 1.3e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal AAA_27 PF13514.1 EGG11333.1 - 0.11 10.1 0.0 0.15 9.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain MerR-DNA-bind PF09278.6 EGG11333.1 - 0.11 12.9 2.6 54 4.2 0.0 3.4 3 0 0 3 3 3 0 MerR, DNA binding NPV_P10 PF05531.7 EGG11333.1 - 0.11 12.7 1.9 1.5 9.1 0.6 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 EGG11333.1 - 4.6 6.8 7.6 4.8 6.7 0.2 3.1 2 1 1 3 3 3 0 Septum formation initiator ADIP PF11559.3 EGG11334.1 - 0.00066 19.5 20.9 0.14 12.0 4.3 3.2 1 1 2 3 3 3 3 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EGG11334.1 - 0.0017 17.5 5.0 0.0017 17.5 3.5 1.8 1 1 1 2 2 2 1 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EGG11334.1 - 0.0035 17.1 1.8 0.0035 17.1 1.3 2.9 1 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 EGG11334.1 - 0.0059 16.7 12.4 0.29 11.2 1.5 3.5 2 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 EGG11334.1 - 0.038 13.8 8.5 1.1 9.2 0.2 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF869 PF05911.6 EGG11334.1 - 0.058 11.6 20.2 0.067 11.4 14.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) TBPIP PF07106.8 EGG11334.1 - 0.064 12.8 20.9 0.17 11.4 1.8 3.1 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EGG11334.1 - 0.071 12.6 23.6 0.17 11.4 3.4 2.4 1 1 1 2 2 2 0 IncA protein DUF342 PF03961.8 EGG11334.1 - 0.073 11.4 14.8 0.035 12.5 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CVNH PF08881.5 EGG11334.1 - 0.081 13.1 2.1 0.44 10.7 1.2 2.4 1 1 1 2 2 2 0 CVNH domain Mit_KHE1 PF10173.4 EGG11334.1 - 0.085 12.6 1.0 0.1 12.4 0.2 1.6 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related GM_CSF PF01109.12 EGG11334.1 - 0.11 12.4 1.1 7.5 6.5 0.1 2.7 2 1 1 3 3 2 0 Granulocyte-macrophage colony-stimulating factor DASH_Dam1 PF08653.5 EGG11334.1 - 0.15 11.8 4.5 0.66 9.7 0.5 3.0 2 0 0 2 2 2 0 DASH complex subunit Dam1 Myosin_tail_1 PF01576.14 EGG11334.1 - 0.22 9.1 14.9 0.41 8.2 10.3 1.5 1 1 0 1 1 1 0 Myosin tail CCDC-167 PF15188.1 EGG11334.1 - 0.5 10.3 15.7 0.95 9.4 0.6 4.0 2 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 Tropomyosin PF00261.15 EGG11334.1 - 0.51 9.3 11.3 0.4 9.7 1.8 2.6 1 1 0 2 2 2 0 Tropomyosin DUF4446 PF14584.1 EGG11334.1 - 0.53 10.0 4.5 1.4 8.7 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) DUF2730 PF10805.3 EGG11334.1 - 0.53 10.0 10.1 4.1 7.1 0.2 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF2730) Cluap1 PF10234.4 EGG11334.1 - 0.63 9.1 15.8 0.014 14.5 1.3 2.7 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF724 PF05266.9 EGG11334.1 - 0.75 9.3 13.1 3.4 7.2 5.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.7 EGG11334.1 - 0.98 9.2 18.1 1.9 8.3 0.6 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) ORF6C PF10552.4 EGG11334.1 - 1.1 8.9 7.7 1 9.0 0.1 3.2 2 1 1 3 3 3 0 ORF6C domain DUF972 PF06156.8 EGG11334.1 - 1.4 9.2 17.7 2.2 8.6 2.8 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 EGG11334.1 - 2.4 7.7 15.8 1.7 8.2 1.8 4.1 1 1 2 4 4 4 0 Septum formation initiator NPV_P10 PF05531.7 EGG11334.1 - 2.5 8.4 16.0 3.4 8.0 0.3 3.7 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.6 EGG11334.1 - 2.9 8.3 8.6 4.2 7.8 0.8 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Kinesin-relat_1 PF12711.2 EGG11334.1 - 3.2 8.2 13.2 0.42 11.0 2.5 3.6 3 1 0 3 3 3 0 Kinesin motor DUF4140 PF13600.1 EGG11334.1 - 3.5 8.1 9.6 13 6.2 0.6 3.4 2 2 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 EGG11334.1 - 5.8 5.8 16.2 1.5 7.8 5.8 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF948 PF06103.6 EGG11334.1 - 7 6.5 7.5 6.2 6.7 0.1 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) LRR_8 PF13855.1 EGG11336.1 - 0.03 14.0 11.8 0.26 11.0 0.1 5.4 3 2 4 7 7 7 0 Leucine rich repeat F-box-like PF12937.2 EGG11336.1 - 0.043 13.5 0.2 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.2 EGG11336.1 - 0.12 11.9 15.5 3.2 7.4 0.3 5.5 5 2 0 6 6 6 0 Leucine Rich repeats (2 copies) PRANC PF09372.5 EGG11336.1 - 0.27 11.2 0.0 0.27 11.2 0.0 2.9 4 0 0 4 4 4 0 PRANC domain LRR_6 PF13516.1 EGG11336.1 - 3.2 8.1 9.0 1.6e+02 2.8 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich repeat AMPKBI PF04739.10 EGG11337.1 - 9.1e-24 83.2 1.1 1.1e-22 79.8 0.0 2.6 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Ras PF00071.17 EGG11338.1 - 2.5e-55 186.2 0.0 2.9e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGG11338.1 - 1.3e-18 67.5 0.0 1.9e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGG11338.1 - 2.1e-07 30.3 0.0 2.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_pol_Rpb8 PF03870.10 EGG11339.1 - 1.3e-43 148.4 0.0 1.5e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Trypan_PARP PF05887.6 EGG11340.1 - 2 8.2 10.0 7 6.4 6.9 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Suf PF05843.9 EGG11340.1 - 4.7 6.8 6.6 0.63 9.7 1.6 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FUSC PF04632.7 EGG11341.1 - 0.034 12.6 5.4 0.059 11.8 3.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family WD40 PF00400.27 EGG11342.1 - 6.2e-08 32.2 6.6 0.0076 16.1 0.5 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase PF00069.20 EGG11343.1 - 3.2e-56 190.3 0.0 1.5e-55 188.1 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11343.1 - 7e-23 81.0 0.0 1.3e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PPP4R2 PF09184.6 EGG11343.1 - 1.4 8.4 0.0 1.4 8.4 0.0 3.0 3 0 0 3 3 3 0 PPP4R2 Ribosomal_L18e PF00828.14 EGG11344.1 - 1.3e-17 64.3 0.0 2.4e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DUF3414 PF11894.3 EGG11345.1 - 5.5e-289 961.7 10.7 7.3e-289 961.3 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) WD40 PF00400.27 EGG11347.1 - 2.3e-35 119.1 26.7 3.1e-05 23.6 0.8 10.1 10 0 0 10 10 10 8 WD domain, G-beta repeat Nup160 PF11715.3 EGG11347.1 - 0.011 13.8 0.4 0.023 12.8 0.2 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Med21 PF11221.3 EGG11349.1 - 1.5e-19 70.3 1.1 1.5e-19 70.3 0.8 2.3 1 1 2 3 3 3 1 Subunit 21 of Mediator complex Lipoprotein_7 PF01540.11 EGG11349.1 - 0.0059 15.7 0.9 0.37 9.8 0.0 2.0 2 0 0 2 2 2 2 Adhesin lipoprotein CENP-R PF06729.7 EGG11349.1 - 0.0087 15.7 1.6 0.026 14.1 1.1 1.9 1 1 0 1 1 1 1 Kinetochore component, CENP-R IncA PF04156.9 EGG11349.1 - 0.021 14.4 1.7 2.9 7.4 0.2 2.2 2 0 0 2 2 2 0 IncA protein Imm22 PF15592.1 EGG11349.1 - 0.13 12.6 0.2 0.53 10.6 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 22 Hormone_1 PF00103.15 EGG11349.1 - 0.14 11.4 0.9 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Somatotropin hormone family SAS4 PF15460.1 EGG11349.1 - 0.15 11.9 1.8 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 ETF PF01012.16 EGG11352.1 - 5.1e-31 107.6 0.0 6.4e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Peptidase_M1 PF01433.15 EGG11353.1 - 6.4e-104 348.1 0.0 6.8e-65 219.6 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 EGG11353.1 - 1.1e-68 231.8 0.0 3.2e-68 230.3 0.0 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGG11353.1 - 7.8e-16 58.2 0.0 2.3e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase MA superfamily CDC37_N PF03234.9 EGG11354.1 - 7.9e-32 110.9 6.9 8.2e-32 110.9 4.8 1.0 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding DUF4303 PF14136.1 EGG11354.1 - 0.086 12.4 0.5 0.093 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) PP2C_C PF07830.8 EGG11354.1 - 0.21 11.7 1.7 0.29 11.2 1.0 1.3 1 1 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Ribosomal_L6e PF01159.14 EGG11354.1 - 0.75 10.0 4.0 0.88 9.8 2.8 1.1 1 0 0 1 1 1 0 Ribosomal protein L6e PRP1_N PF06424.7 EGG11354.1 - 1.2 9.4 5.4 1.3 9.3 3.8 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Omptin PF01278.15 EGG11355.1 - 0.11 11.5 0.0 0.25 10.3 0.0 1.5 2 0 0 2 2 2 0 Omptin family Alpha_kinase PF02816.13 EGG11357.1 - 4.6e-10 39.4 0.0 7.8e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family GAF PF01590.21 EGG11359.1 - 0.00013 22.1 0.0 0.00017 21.7 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EGG11359.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.6 1 1 0 1 1 1 0 GAF domain AlkA_N PF06029.6 EGG11359.1 - 0.15 12.1 0.1 30 4.7 0.0 2.8 2 1 0 2 2 2 0 AlkA N-terminal domain GAF PF01590.21 EGG11360.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 GAF domain DUF1764 PF08576.5 EGG11361.1 - 0.053 14.2 0.1 0.058 14.1 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Pkinase PF00069.20 EGG11362.1 - 1.1e-47 162.3 0.0 1.2e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11362.1 - 2.5e-29 102.1 0.0 3.3e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG11362.1 - 0.006 15.5 0.0 0.011 14.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGG11362.1 - 0.0091 15.7 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGG11362.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EGG11362.1 - 0.043 12.8 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3759 PF12585.3 EGG11363.1 - 1.7e-35 120.7 5.9 2.1e-35 120.4 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Duffy_binding PF05424.6 EGG11363.1 - 0.063 13.0 0.2 0.072 12.9 0.1 1.2 1 0 0 1 1 1 0 Duffy binding domain Peptidase_A8 PF01252.13 EGG11363.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Signal peptidase (SPase) II AOX PF01786.12 EGG11365.1 - 1.7e-81 272.5 0.0 2.1e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase zf-C2H2 PF00096.21 EGG11366.1 - 6e-16 57.7 62.0 0.0073 16.5 2.2 9.9 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG11366.1 - 4.7e-09 35.9 57.5 0.004 17.3 2.3 9.1 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGG11366.1 - 9e-06 25.7 10.1 1.5e-05 24.9 3.0 10.2 9 3 1 10 10 10 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGG11366.1 - 0.00035 20.6 32.5 0.062 13.4 1.4 8.2 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGG11366.1 - 0.035 13.9 19.2 0.76 9.7 0.1 6.3 6 0 0 6 6 6 0 C2H2-type zinc finger GAF PF01590.21 EGG11367.1 - 0.091 12.8 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 GAF domain OKR_DC_1 PF01276.15 EGG11370.1 - 0.094 11.2 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain F-box-like_2 PF13013.1 EGG11371.1 - 0.00054 19.6 0.4 1.8 8.3 0.1 3.6 3 0 0 3 3 3 2 F-box-like domain F-box-like PF12937.2 EGG11371.1 - 0.00067 19.3 0.0 0.0021 17.7 0.0 1.9 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGG11371.1 - 0.062 12.9 7.4 1.9 8.2 0.7 5.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EGG11371.1 - 0.71 10.1 2.7 44 4.5 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat WD40 PF00400.27 EGG11373.1 - 2e-22 78.1 18.2 5.2e-10 38.8 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EGG11373.1 - 0.003 17.3 4.0 0.003 17.3 2.8 2.2 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term CWC25 PF12542.3 EGG11373.1 - 0.16 12.4 1.5 0.3 11.5 1.1 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor Chitin_bind_1 PF00187.14 EGG11374.1 - 0.095 12.7 1.6 0.17 11.9 1.1 1.3 1 0 0 1 1 1 0 Chitin recognition protein Pyr_redox_3 PF13738.1 EGG11376.1 - 2.9e-17 63.4 0.1 3.8e-16 59.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGG11376.1 - 3.5e-15 55.2 0.0 3.6e-14 51.8 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.22 EGG11376.1 - 2.2e-11 43.9 0.7 0.00023 21.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGG11376.1 - 7.1e-11 41.9 0.6 4.9e-08 32.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGG11376.1 - 2.4e-10 40.6 0.2 3.4e-08 33.6 0.7 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGG11376.1 - 1.9e-08 33.6 1.0 2e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGG11376.1 - 3.9e-08 33.2 1.5 3.9e-05 23.4 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EGG11376.1 - 7.2e-08 31.7 0.0 1.1e-05 24.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EGG11376.1 - 1.2e-06 27.3 2.2 0.012 14.1 0.2 2.5 3 0 0 3 3 3 2 HI0933-like protein 3HCDH_N PF02737.13 EGG11376.1 - 6.6e-06 25.8 0.9 0.00028 20.5 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EGG11376.1 - 6.7e-06 25.7 1.3 0.084 12.4 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EGG11376.1 - 9e-06 25.8 0.4 0.095 12.7 0.0 2.7 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EGG11376.1 - 3e-05 23.0 1.5 0.08 11.7 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EGG11376.1 - 6.9e-05 23.0 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.12 EGG11376.1 - 9.8e-05 21.5 1.7 0.01 14.9 0.1 2.8 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 EGG11376.1 - 0.00034 19.5 3.4 0.0076 15.1 0.2 2.6 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EGG11376.1 - 0.00085 18.5 0.1 0.61 9.2 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EGG11376.1 - 0.0053 15.8 0.0 0.015 14.4 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_10 PF13460.1 EGG11376.1 - 0.0086 16.1 1.0 1.5 8.8 0.1 2.9 3 0 0 3 3 3 1 NADH(P)-binding FAD_oxidored PF12831.2 EGG11376.1 - 0.018 14.1 6.7 0.13 11.3 0.1 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGG11376.1 - 0.02 13.9 4.8 0.021 13.8 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EGG11376.1 - 0.023 13.6 0.9 2 7.2 0.0 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein NAD_binding_2 PF03446.10 EGG11376.1 - 0.028 14.2 0.5 0.049 13.4 0.0 1.5 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EGG11376.1 - 0.041 13.2 0.4 3.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 EGG11376.1 - 0.062 13.0 2.5 0.33 10.6 0.1 2.5 2 1 1 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EGG11376.1 - 0.085 12.2 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Malic_M PF03949.10 EGG11376.1 - 0.18 11.3 0.3 0.61 9.5 0.0 1.9 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain ThiF PF00899.16 EGG11376.1 - 4.3 7.1 5.6 23 4.7 0.5 3.0 3 0 0 3 3 3 0 ThiF family DUF962 PF06127.6 EGG11377.1 - 0.094 12.6 0.7 0.66 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF962) DUF4405 PF14358.1 EGG11377.1 - 4.8 7.3 7.3 1.6 8.9 2.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Band_7 PF01145.20 EGG11378.1 - 1.3e-23 83.8 1.2 2.1e-23 83.1 0.8 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family RabGAP-TBC PF00566.13 EGG11379.1 - 1.6e-52 178.1 0.2 2.2e-52 177.6 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2404 PF10296.4 EGG11380.1 - 0.0024 17.9 0.0 0.017 15.2 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) GAGA PF09237.6 EGG11380.1 - 0.13 11.8 0.1 0.49 10.0 0.1 1.9 1 0 0 1 1 1 0 GAGA factor DUF536 PF04394.9 EGG11387.1 - 0.062 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF536 Ribosomal_L35p PF01632.14 EGG11394.1 - 2.5e-16 59.3 8.2 4.8e-16 58.4 5.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L35 IBR PF01485.16 EGG11395.1 - 0.031 14.1 0.6 0.069 13.0 0.4 1.5 1 0 0 1 1 1 0 IBR domain zf-Di19 PF05605.7 EGG11395.1 - 0.037 14.1 0.1 0.058 13.5 0.1 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding PRP21_like_P PF12230.3 EGG11395.1 - 0.093 12.2 1.1 0.16 11.4 0.8 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-TRAF PF02176.13 EGG11395.1 - 0.25 11.7 0.9 1.1 9.7 0.6 1.9 1 1 1 2 2 2 0 TRAF-type zinc finger Abhydrolase_6 PF12697.2 EGG11396.1 - 9.7e-12 45.2 0.0 1.5e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG11396.1 - 3.6e-05 23.4 0.0 0.0002 20.9 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG11396.1 - 0.15 11.7 0.0 0.33 10.7 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S24 PF00717.18 EGG11400.1 - 2.5e-09 36.6 0.1 7.6e-09 35.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase S24-like Ribosomal_S10 PF00338.17 EGG11401.1 - 0.033 14.0 0.1 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e MCM PF00493.18 EGG11402.1 - 4.3e-141 469.5 0.6 5.6e-141 469.1 0.4 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGG11402.1 - 2.6e-17 63.4 0.4 7.6e-17 61.9 0.1 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGG11402.1 - 3.1e-06 26.5 0.0 0.00063 18.9 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGG11402.1 - 8.5e-06 25.5 0.0 3.2e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGG11402.1 - 0.00023 20.7 0.1 0.0018 17.8 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EGG11402.1 - 0.013 15.9 0.8 0.042 14.2 0.2 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EGG11402.1 - 0.027 13.9 0.0 1.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Proteasome PF00227.21 EGG11403.1 - 3.1e-42 144.0 0.0 3.5e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M24 PF00557.19 EGG11404.1 - 2.9e-43 147.8 0.1 3.7e-43 147.5 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 NST1 PF13945.1 EGG11404.1 - 0.027 14.5 2.0 0.041 13.9 1.4 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Cnd2 PF05786.9 EGG11404.1 - 2.6 6.4 7.8 3.6 5.9 5.4 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 HSP90 PF00183.13 EGG11404.1 - 6.2 5.1 8.2 11 4.3 5.7 1.3 1 0 0 1 1 1 0 Hsp90 protein Pdase_C33_assoc PF14756.1 EGG11405.1 - 0.0026 17.4 1.2 0.0029 17.3 0.9 1.2 1 0 0 1 1 1 1 Peptidase_C33-associated domain NPV_P10 PF05531.7 EGG11407.1 - 0.008 16.4 3.9 0.091 13.0 0.0 3.9 4 0 0 4 4 4 1 Nucleopolyhedrovirus P10 protein Med9 PF07544.8 EGG11407.1 - 0.44 10.3 9.6 2.8 7.7 2.1 4.1 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 UBN_AB PF14075.1 EGG11408.1 - 0.0059 16.3 0.5 0.01 15.5 0.3 1.5 1 1 0 1 1 1 1 Ubinuclein conserved middle domain DnaJ-X PF14308.1 EGG11408.1 - 0.0093 15.2 0.8 0.017 14.4 0.5 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing PTPS_related PF10131.4 EGG11408.1 - 0.15 10.1 0.1 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Peptidase_C48 PF02902.14 EGG11411.1 - 5.7e-11 42.4 0.3 8.7e-11 41.8 0.2 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DNase_II PF03265.10 EGG11411.1 - 0.017 14.1 0.2 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 Deoxyribonuclease II Lep_receptor_Ig PF06328.6 EGG11411.1 - 0.055 13.3 0.4 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 Ig-like C2-type domain MSA-2c PF12238.3 EGG11411.1 - 0.071 12.7 0.4 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c T2SF PF00482.18 EGG11415.1 - 0.0048 16.8 0.1 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F DUF445 PF04286.7 EGG11415.1 - 0.096 12.1 5.4 0.13 11.7 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) GM_CSF PF01109.12 EGG11415.1 - 2.2 8.2 8.0 4.7 7.1 2.8 2.5 1 1 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor Alpha-amylase PF00128.19 EGG11416.1 - 0.03 13.7 1.0 0.037 13.4 0.7 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain RXT2_N PF08595.6 EGG11416.1 - 0.11 12.3 8.8 0.11 12.3 5.6 1.4 1 1 0 1 1 1 0 RXT2-like, N-terminal TFIIA PF03153.8 EGG11416.1 - 0.17 11.7 12.6 0.2 11.5 8.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec62 PF03839.11 EGG11416.1 - 8.1 5.7 10.4 5 6.4 6.2 1.4 1 1 0 1 1 1 0 Translocation protein Sec62 HAUS6_N PF14661.1 EGG11416.1 - 8.6 5.6 15.4 11 5.3 10.7 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus MRG PF05712.8 EGG11418.1 - 3.4e-19 68.5 0.2 4.3e-19 68.1 0.1 1.0 1 0 0 1 1 1 1 MRG REC114-like PF15165.1 EGG11420.1 - 0.64 9.7 4.6 0.97 9.1 3.2 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like DUF4218 PF13960.1 EGG11422.1 - 8.1e-05 22.0 0.2 0.00015 21.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Fic_N PF13784.1 EGG11423.1 - 0.031 14.1 0.0 0.043 13.6 0.0 1.1 1 0 0 1 1 1 0 Fic/DOC family N-terminal Methyltransf_PK PF05891.7 EGG11424.1 - 0.0029 16.9 0.0 0.0036 16.6 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase GTP_EFTU PF00009.22 EGG11429.1 - 2e-43 148.0 0.0 2.8e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGG11429.1 - 8.2e-26 89.9 0.0 1.8e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EGG11429.1 - 4.4e-19 68.1 0.0 1.1e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 EGG11429.1 - 2.2e-08 34.0 0.1 4.2e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGG11429.1 - 1.8e-06 28.4 0.1 3.6e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 EGG11429.1 - 4e-06 26.8 0.1 8.3e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGG11429.1 - 0.00026 20.7 0.0 0.00072 19.3 0.0 1.7 2 0 0 2 2 2 1 Elongation Factor G, domain II SRPRB PF09439.5 EGG11429.1 - 0.0011 18.1 0.1 0.0023 17.2 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EGG11429.1 - 0.0032 17.3 0.1 0.34 10.7 0.0 2.3 2 0 0 2 2 2 1 Dynamin family GBP PF02263.14 EGG11429.1 - 0.052 12.6 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Ras PF00071.17 EGG11429.1 - 0.09 12.1 0.0 0.32 10.3 0.0 1.8 1 1 0 1 1 1 0 Ras family GTP_cyclohydroI PF01227.17 EGG11430.1 - 5.9e-74 247.2 0.1 7.6e-74 246.8 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EGG11430.1 - 0.00023 21.0 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 QueF-like protein IBN_N PF03810.14 EGG11431.1 - 6.7e-07 29.1 0.0 7e-06 25.8 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.5 EGG11431.1 - 8.4e-05 21.2 0.2 0.00052 18.6 0.0 2.4 3 0 0 3 3 3 1 Cse1 Xpo1 PF08389.7 EGG11431.1 - 0.011 15.6 3.5 0.16 11.8 0.0 4.7 6 1 0 6 6 6 0 Exportin 1-like protein DUF4611 PF15387.1 EGG11431.1 - 0.013 15.6 0.5 0.013 15.6 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) DUF3295 PF11702.3 EGG11431.1 - 2.8 6.8 4.3 5.6 5.8 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Peptidase_M16 PF00675.15 EGG11432.1 - 5e-19 68.5 0.0 8.6e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGG11432.1 - 2.4e-07 30.5 0.0 1.7e-06 27.8 0.0 2.5 2 1 0 2 2 2 1 Peptidase M16 inactive domain HCaRG PF07258.9 EGG11432.1 - 0.08 12.4 0.1 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 HCaRG protein HLH PF00010.21 EGG11433.1 - 4.7e-12 45.4 0.1 1.7e-11 43.5 0.1 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4359 PF14271.1 EGG11435.1 - 0.035 14.4 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4359) Sec62 PF03839.11 EGG11437.1 - 1.8 7.9 6.2 2.2 7.6 4.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2052 PF09747.4 EGG11438.1 - 0.16 11.8 3.9 0.24 11.2 2.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) V-SNARE PF05008.10 EGG11441.1 - 4.2e-18 65.2 6.5 1.2e-15 57.4 2.3 2.6 2 0 0 2 2 2 2 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EGG11441.1 - 9.1e-16 57.6 3.1 9.1e-16 57.6 2.2 2.1 2 0 0 2 2 1 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.6 EGG11441.1 - 0.00065 17.3 3.6 0.00096 16.8 2.5 1.2 1 0 0 1 1 1 1 Prominin Laminin_I PF06008.9 EGG11441.1 - 0.0086 15.4 10.7 0.028 13.7 2.0 2.3 2 1 0 2 2 2 2 Laminin Domain I Baculo_PEP_C PF04513.7 EGG11441.1 - 0.024 14.4 6.0 0.18 11.6 1.4 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ScpA_ScpB PF02616.9 EGG11441.1 - 0.03 13.8 1.1 0.24 10.9 0.2 2.0 2 0 0 2 2 2 0 ScpA/B protein ApoLp-III PF07464.6 EGG11441.1 - 0.049 13.6 4.3 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Laminin_II PF06009.7 EGG11441.1 - 0.091 12.5 3.7 5.5 6.7 1.0 2.2 2 0 0 2 2 2 0 Laminin Domain II Pepsin-I3 PF06394.8 EGG11441.1 - 0.13 11.9 0.6 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DUF3708 PF12501.3 EGG11441.1 - 0.24 11.2 2.3 2.8 7.7 0.6 2.1 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter Sec8_exocyst PF04048.9 EGG11441.1 - 0.3 10.7 5.5 4.1 7.0 0.0 2.8 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain Flagellin_N PF00669.15 EGG11441.1 - 0.32 10.7 9.1 0.13 12.0 1.9 2.3 1 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region Cytochrom_B562 PF07361.6 EGG11441.1 - 0.42 11.0 3.6 1.9 8.9 0.7 2.6 2 1 1 3 3 3 0 Cytochrome b562 DASH_Duo1 PF08651.5 EGG11441.1 - 0.67 9.5 4.0 0.85 9.2 0.1 2.8 3 1 0 3 3 3 0 DASH complex subunit Duo1 NPV_P10 PF05531.7 EGG11441.1 - 0.84 9.9 3.4 3 8.1 0.3 2.5 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.10 EGG11441.1 - 0.92 8.6 11.7 0.5 9.5 3.5 1.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF745 PF05335.8 EGG11441.1 - 1.5 8.2 7.0 2.4 7.6 3.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF342 PF03961.8 EGG11441.1 - 1.7 6.9 6.5 2.6 6.3 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) NADHdh_A3 PF14987.1 EGG11444.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Ribonuc_red_lgN PF00317.16 EGG11445.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain Ribosomal_L18p PF00861.17 EGG11447.1 - 1.8e-44 150.7 0.1 4.9e-44 149.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EGG11447.1 - 1.1e-28 99.6 6.0 1.1e-28 99.6 4.1 1.6 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DAG_kinase_N PF14513.1 EGG11447.1 - 0.045 13.9 0.9 0.084 13.0 0.6 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Metal_resist PF13801.1 EGG11447.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Heavy-metal resistance MtrA PF04208.9 EGG11447.1 - 0.073 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A Aminotran_5 PF00266.14 EGG11448.1 - 7e-95 317.8 0.0 8.1e-95 317.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGG11448.1 - 1.5e-06 27.5 0.0 1.9e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGG11448.1 - 0.00024 20.2 0.1 0.0006 18.9 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family B12-binding PF02310.14 EGG11448.1 - 0.0065 16.3 0.0 0.54 10.1 0.0 2.5 2 0 0 2 2 2 1 B12 binding domain Cys_Met_Meta_PP PF01053.15 EGG11448.1 - 0.08 11.2 0.1 0.12 10.6 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Cauli_AT PF03233.8 EGG11449.1 - 0.036 13.7 0.5 0.036 13.7 0.3 1.9 2 1 0 2 2 2 0 Aphid transmission protein DUF1870 PF08965.5 EGG11449.1 - 0.046 13.3 0.6 0.5 10.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) UBN2_3 PF14244.1 EGG11451.1 - 0.0078 15.7 0.6 0.088 12.3 0.0 2.4 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type CDC27 PF09507.5 EGG11452.1 - 2.9 6.9 32.6 4.9 6.2 22.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4321 PF14209.1 EGG11453.1 - 2.6 7.7 6.5 20 4.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4321) Amnionless PF14828.1 EGG11454.1 - 0.0036 15.8 0.0 0.005 15.3 0.0 1.1 1 0 0 1 1 1 1 Amnionless DUF2805 PF10985.3 EGG11454.1 - 0.091 12.7 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) Amnionless PF14828.1 EGG11455.1 - 0.00042 18.9 0.0 0.00054 18.5 0.0 1.1 1 0 0 1 1 1 1 Amnionless DNA_alkylation PF08713.6 EGG11455.1 - 0.022 14.2 0.3 1.2 8.6 0.0 2.0 1 1 1 2 2 2 0 DNA alkylation repair enzyme TAFH PF07531.9 EGG11455.1 - 0.033 13.8 0.1 1.5 8.5 0.0 2.7 2 1 1 3 3 3 0 NHR1 homology to TAF DUF1639 PF07797.9 EGG11455.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) ORC6 PF05460.8 EGG11456.1 - 0.31 10.1 9.4 0.41 9.7 6.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF912 PF06024.7 EGG11456.1 - 7.4 6.6 0.0 7.4 6.6 0.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SQS_PSY PF00494.14 EGG11457.1 - 4.5e-24 85.1 0.0 5.8e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RNase_PH PF01138.16 EGG11458.1 - 2.6e-23 82.7 0.3 3.8e-23 82.2 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGG11458.1 - 0.00047 20.0 0.0 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 TBCC PF07986.7 EGG11459.1 - 2.5e-12 46.2 0.4 8.4e-12 44.5 0.2 1.9 1 1 1 2 2 2 1 Tubulin binding cofactor C TcdB_N PF12918.2 EGG11459.1 - 0.6 10.2 4.8 8.8 6.4 0.4 2.6 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain FlxA PF14282.1 EGG11459.1 - 9.6 6.2 7.6 0.43 10.5 0.5 2.1 2 1 0 2 2 2 0 FlxA-like protein E1_dh PF00676.15 EGG11462.1 - 6e-87 291.1 0.0 7.3e-87 290.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 EGG11462.1 - 6.2e-07 28.5 0.1 8.2e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Y_phosphatase2 PF03162.8 EGG11463.1 - 4.1e-40 136.8 0.0 6.6e-40 136.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EGG11463.1 - 6.3e-05 23.2 0.0 0.00031 21.0 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family LRR_4 PF12799.2 EGG11466.1 - 3 7.5 11.1 8.5 6.1 0.5 4.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) PXT1 PF15214.1 EGG11467.1 - 0.015 15.5 1.9 0.075 13.2 0.3 2.5 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 Gly-zipper_Omp PF13488.1 EGG11467.1 - 0.65 9.6 70.6 0.14 11.8 15.5 3.2 2 1 1 3 3 3 0 Glycine zipper Rick_17kDa_Anti PF05433.10 EGG11467.1 - 2.7 7.7 63.5 0.087 12.5 14.8 2.8 2 0 0 2 2 2 0 Glycine zipper 2TM domain WD40 PF00400.27 EGG11470.1 - 9.6e-28 95.0 11.3 1.5e-10 40.5 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGG11470.1 - 0.025 14.3 0.0 3.9 7.2 0.0 3.2 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PHTB1_C PF14728.1 EGG11470.1 - 0.1 11.3 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus Ist1 PF03398.9 EGG11471.1 - 4.1e-56 188.9 3.4 4.8e-56 188.7 2.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RelB PF04221.7 EGG11471.1 - 0.028 14.1 0.1 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 RelB antitoxin Indigoidine_A PF04227.7 EGG11471.1 - 0.11 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Indigoidine synthase A like protein EF-hand_1 PF00036.27 EGG11472.1 - 1.3e-07 30.3 0.4 9.3e-05 21.4 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EGG11472.1 - 8.3e-07 28.3 0.2 0.025 14.4 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EGG11472.1 - 7.5e-06 25.9 0.8 7.5e-06 25.9 0.6 2.5 2 2 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EGG11472.1 - 2.5e-05 23.4 0.0 0.0062 15.8 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EGG11472.1 - 0.00098 18.6 0.0 0.043 13.4 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair DUF3189 PF11385.3 EGG11472.1 - 0.032 13.7 0.4 0.43 10.1 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3189) DUF812 PF05667.6 EGG11472.1 - 0.063 11.7 2.9 0.077 11.5 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Histone_HNS PF00816.16 EGG11472.1 - 0.49 10.9 5.7 0.44 11.0 2.4 2.1 2 0 0 2 2 2 0 H-NS histone family SPARC_Ca_bdg PF10591.4 EGG11472.1 - 2.4 8.2 6.9 1.9 8.5 0.3 3.0 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3678 PF12435.3 EGG11475.1 - 0.1 12.1 0.3 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) EF1_GNE PF00736.14 EGG11479.1 - 1.4e-29 101.6 2.1 1.4e-29 101.6 1.4 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EGG11479.1 - 4.3e-13 49.1 5.9 4.3e-13 49.1 4.1 2.3 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EGG11479.1 - 0.0078 16.6 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_M16 PF00675.15 EGG11482.1 - 8.3e-37 126.2 0.0 1.3e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGG11482.1 - 1.1e-28 100.2 0.0 6.2e-28 97.7 0.0 2.3 2 1 0 2 2 2 1 Peptidase M16 inactive domain Pkinase PF00069.20 EGG11483.1 - 3.5e-13 49.3 0.0 4.1e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11483.1 - 2.2e-07 30.1 0.0 2.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGEF PF00621.15 EGG11484.1 - 2.5e-28 99.1 0.0 5.1e-27 94.9 0.0 2.2 1 1 0 1 1 1 1 RhoGEF domain zf-CCHC PF00098.18 EGG11486.1 - 0.0054 16.6 0.9 0.012 15.4 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EGG11486.1 - 0.0063 16.5 0.2 0.026 14.5 0.0 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein FKBP_C PF00254.23 EGG11487.1 - 4.8e-34 116.2 0.0 6e-34 115.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ART PF01129.13 EGG11488.1 - 0.063 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Ycf1 PF05758.7 EGG11490.1 - 0.24 9.0 1.2 0.26 8.9 0.9 1.0 1 0 0 1 1 1 0 Ycf1 DUF2201_N PF13203.1 EGG11490.1 - 5.7 6.0 7.5 6.6 5.8 5.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain NOA36 PF06524.7 EGG11490.1 - 9.2 5.4 7.8 11 5.1 5.4 1.1 1 0 0 1 1 1 0 NOA36 protein DDE_3 PF13358.1 EGG11493.1 - 0.035 13.8 0.1 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease HSCB_C PF07743.8 EGG11498.1 - 0.26 11.7 1.4 0.55 10.7 1.0 1.5 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain Prefoldin_2 PF01920.15 EGG11501.1 - 3.2e-08 33.2 5.6 3.2e-08 33.2 3.9 1.7 1 1 0 1 1 1 1 Prefoldin subunit Xol-1_GHMP-like PF09109.5 EGG11501.1 - 0.026 14.6 0.4 0.03 14.4 0.2 1.3 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like DUF3683 PF12447.3 EGG11501.1 - 0.044 13.6 0.4 0.072 12.9 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3683) DUF4200 PF13863.1 EGG11501.1 - 0.12 12.3 15.0 0.13 12.1 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GAS PF13851.1 EGG11501.1 - 0.13 11.4 10.7 0.37 9.9 1.5 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 EGG11501.1 - 1.1 9.2 6.3 0.36 10.7 0.6 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Aida_N PF08910.5 EGG11501.1 - 1.2 9.4 3.7 0.49 10.6 0.3 1.8 2 0 0 2 2 2 0 Aida N-terminus Wbp11 PF09429.5 EGG11501.1 - 2.7 8.0 10.5 3.3 7.7 1.6 2.6 1 1 1 2 2 2 0 WW domain binding protein 11 FlgN PF05130.7 EGG11501.1 - 4.1 7.6 9.9 1.1 9.5 1.2 2.3 1 1 0 2 2 2 0 FlgN protein Cortex-I_coil PF09304.5 EGG11501.1 - 6.5 6.8 13.6 0.43 10.6 2.6 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil Tropomyosin_1 PF12718.2 EGG11501.1 - 8.9 6.1 12.7 0.16 11.8 2.6 2.1 2 1 0 2 2 2 0 Tropomyosin like zf-C2HC5 PF06221.8 EGG11502.1 - 2.5e-07 30.3 4.4 6e-07 29.1 3.1 1.7 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Gcd10p PF04189.8 EGG11505.1 - 1.4e-69 234.5 0.0 2.1e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family polyprenyl_synt PF00348.12 EGG11506.1 - 4.1e-42 143.8 0.0 1.4e-40 138.8 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Nepo_coat_C PF03688.9 EGG11507.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain Fimbrial_K88 PF02432.10 EGG11507.1 - 0.088 12.2 0.2 5.3 6.4 0.1 2.0 2 0 0 2 2 2 0 Fimbrial, major and minor subunit Tektin PF03148.9 EGG11508.1 - 0.003 16.1 0.1 0.0045 15.5 0.1 1.2 1 0 0 1 1 1 1 Tektin family Baculo_PEP_C PF04513.7 EGG11508.1 - 0.034 13.9 0.5 0.06 13.1 0.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1043 PF06295.7 EGG11508.1 - 0.085 12.5 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) MIF4G PF02854.14 EGG11512.1 - 1.3e-11 44.3 0.0 2.4e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EGG11512.1 - 0.00038 20.1 0.0 0.00095 18.8 0.0 1.7 1 0 0 1 1 1 1 MA3 domain PIN_2 PF10130.4 EGG11512.1 - 0.13 12.2 0.5 3.1 7.8 0.3 2.3 2 0 0 2 2 2 0 PIN domain DUF2360 PF10152.4 EGG11512.1 - 8.1 6.7 10.9 37 4.5 0.1 2.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) CUE PF02845.11 EGG11513.1 - 1e-07 31.3 0.0 1.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 EGG11513.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain DUF1296 PF06972.6 EGG11513.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Myosin_head PF00063.16 EGG11514.1 - 6.4e-222 738.4 0.5 1.1e-221 737.6 0.3 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EGG11514.1 - 3.2e-42 144.0 0.0 5.2e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Myosin tail SH3_9 PF14604.1 EGG11514.1 - 7.4e-13 47.8 0.3 2.4e-12 46.2 0.2 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGG11514.1 - 1.7e-10 40.1 0.5 4.7e-10 38.8 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EGG11514.1 - 3.9e-09 35.7 0.4 9.1e-09 34.5 0.3 1.7 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 EGG11514.1 - 0.00044 20.3 0.6 0.001 19.2 0.4 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 EGG11514.1 - 0.0065 16.6 0.1 0.019 15.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGG11514.1 - 0.044 14.6 2.0 0.1 13.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGG11514.1 - 0.059 12.4 2.6 0.11 11.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Hpr_kinase_C PF07475.7 EGG11514.1 - 0.066 12.5 0.1 2.7 7.2 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.7 EGG11514.1 - 0.17 11.4 0.0 0.44 10.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EGG11514.1 - 0.21 11.5 0.0 0.8 9.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain IQ PF00612.22 EGG11514.1 - 0.26 11.0 6.8 2.7 7.8 0.3 2.9 1 1 1 2 2 2 0 IQ calmodulin-binding motif AAA_18 PF13238.1 EGG11514.1 - 0.31 11.3 1.1 0.61 10.3 0.1 2.1 2 0 0 2 2 1 0 AAA domain Mito_carr PF00153.22 EGG11517.1 - 3.1e-57 190.2 1.1 1.3e-18 66.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_43 PF04616.9 EGG11518.1 - 3.4e-29 101.8 0.1 4.6e-29 101.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.9 EGG11519.1 - 1e-29 103.5 0.2 1.5e-29 103.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 COX6A PF02046.10 EGG11521.1 - 9.1e-31 106.1 0.0 1e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa CAP PF00188.21 EGG11522.1 - 1.1e-10 42.0 0.7 1.1e-10 42.0 0.5 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Velvet PF11754.3 EGG11523.1 - 9.7e-42 142.8 0.1 1.9e-33 115.8 0.0 2.2 2 0 0 2 2 2 2 Velvet factor Lgl_C PF08596.5 EGG11524.1 - 2.1e-11 42.9 0.0 2.2e-09 36.2 0.0 3.2 3 1 0 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EGG11524.1 - 3.5e-07 29.8 0.1 0.00065 19.4 0.0 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Synaptobrevin PF00957.16 EGG11524.1 - 0.00015 21.2 3.3 0.00032 20.2 2.3 1.4 1 0 0 1 1 1 1 Synaptobrevin CAP PF00188.21 EGG11525.1 - 2.2e-15 57.2 0.9 1.1e-14 55.0 0.3 2.1 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Autophagy_act_C PF03987.10 EGG11526.1 - 1.7e-13 50.4 7.7 1.7e-12 47.3 3.1 3.1 2 1 0 2 2 2 1 Autophagocytosis associated protein, active-site domain FAM163 PF15069.1 EGG11529.1 - 0.21 12.1 5.8 0.64 10.5 0.0 3.2 3 1 0 3 3 3 0 FAM163 family Glycoprotein_B PF00606.13 EGG11531.1 - 0.06 11.3 1.0 0.067 11.2 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Chlorosome_CsmC PF11098.3 EGG11531.1 - 0.21 11.3 7.6 0.28 10.8 5.3 1.2 1 0 0 1 1 1 0 Chlorosome envelope protein C Bacteriocin_IIc PF10439.4 EGG11531.1 - 0.29 11.2 17.8 0.12 12.4 2.3 2.3 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DnaJ PF00226.26 EGG11532.1 - 2.8e-12 46.1 0.1 2.8e-12 46.1 0.1 2.7 3 0 0 3 3 3 1 DnaJ domain GIT_SHD PF08518.6 EGG11533.1 - 9.1e-23 79.2 9.3 1.9e-11 43.1 2.0 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT MAD PF05557.8 EGG11533.1 - 0.00099 17.3 17.4 0.00099 17.3 12.1 2.4 1 1 1 2 2 2 1 Mitotic checkpoint protein V_ATPase_I PF01496.14 EGG11533.1 - 0.0016 16.4 7.1 0.0016 16.4 4.9 2.2 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family Tropomyosin PF00261.15 EGG11533.1 - 0.005 15.9 35.1 0.005 15.9 24.3 2.3 2 0 0 2 2 2 1 Tropomyosin TPR_MLP1_2 PF07926.7 EGG11533.1 - 0.048 13.4 32.0 0.37 10.5 12.1 3.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EGG11533.1 - 0.079 11.9 32.5 0.032 13.2 8.0 2.6 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EGG11533.1 - 0.085 12.7 36.3 0.16 11.8 3.5 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EGG11533.1 - 1.2 8.7 43.4 5.7 6.4 24.0 4.6 3 1 1 4 4 4 0 IncA protein FUSC PF04632.7 EGG11533.1 - 2.6 6.3 8.5 13 4.0 5.4 2.2 3 0 0 3 3 3 0 Fusaric acid resistance protein family Atg14 PF10186.4 EGG11533.1 - 3.6 6.4 30.7 1.3 7.9 4.1 3.8 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3584 PF12128.3 EGG11533.1 - 3.7 4.7 32.7 9 3.4 20.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) Mito_carr PF00153.22 EGG11534.1 - 6e-35 118.8 0.0 8.9e-12 44.5 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2_2 PF12756.2 EGG11535.1 - 0.048 13.7 0.1 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EGG11535.1 - 0.062 13.5 1.5 9.7 6.5 2.8 2.9 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGG11535.1 - 0.27 11.4 4.6 0.86 9.8 2.1 2.5 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DHC_N1 PF08385.7 EGG11538.1 - 5e-183 609.6 7.4 5e-183 609.6 5.1 4.2 5 0 0 5 5 5 2 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.10 EGG11538.1 - 1.2e-174 582.2 0.0 2.2e-174 581.3 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 EGG11538.1 - 4.4e-126 420.6 5.6 4.4e-126 420.6 3.9 4.4 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EGG11538.1 - 1.9e-82 276.2 0.0 4.3e-82 275.1 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 MT PF12777.2 EGG11538.1 - 2.2e-45 154.9 6.3 3.8e-45 154.1 4.4 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 EGG11538.1 - 2.1e-44 151.0 0.0 8.5e-44 149.0 0.0 2.1 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EGG11538.1 - 3.3e-44 150.8 0.2 8.3e-43 146.2 0.1 2.7 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 EGG11538.1 - 4.2e-27 94.5 0.0 2.7e-11 43.3 0.0 5.9 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EGG11538.1 - 9.4e-19 67.5 0.0 2.5e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA PF00004.24 EGG11538.1 - 3.9e-12 46.4 0.5 0.0048 17.0 0.0 5.4 6 0 0 6 6 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGG11538.1 - 6.1e-12 45.8 1.0 0.02 15.0 0.0 6.8 7 0 0 7 7 7 2 AAA domain AAA_33 PF13671.1 EGG11538.1 - 1.1e-08 35.1 5.1 0.3 10.9 0.0 6.0 6 0 0 6 6 6 3 AAA domain AAA_17 PF13207.1 EGG11538.1 - 8.2e-08 33.0 0.1 0.074 13.8 0.0 6.1 5 0 0 5 5 5 1 AAA domain AAA_18 PF13238.1 EGG11538.1 - 2.9e-07 30.8 1.8 0.075 13.3 0.0 5.5 5 0 0 5 5 5 1 AAA domain AAA_19 PF13245.1 EGG11538.1 - 9.8e-06 25.2 0.1 1.2 8.9 0.0 4.5 4 0 0 4 4 4 1 Part of AAA domain T2SE PF00437.15 EGG11538.1 - 2.7e-05 23.2 0.0 0.038 12.8 0.0 3.0 2 0 0 2 2 2 2 Type II/IV secretion system protein Mg_chelatase PF01078.16 EGG11538.1 - 0.00013 21.1 0.1 0.75 8.9 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EGG11538.1 - 0.0003 20.8 8.3 0.18 11.7 0.2 6.7 5 1 1 6 6 6 1 AAA ATPase domain AAA_29 PF13555.1 EGG11538.1 - 0.011 15.2 0.0 0.95 9.0 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EGG11538.1 - 0.059 13.6 1.1 7.4 6.8 0.0 3.9 4 0 0 4 4 2 0 ABC transporter DUF390 PF04094.9 EGG11538.1 - 0.34 8.9 5.9 0.58 8.1 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Mpv17_PMP22 PF04117.7 EGG11539.1 - 4.8e-23 80.5 2.9 8.5e-23 79.7 2.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DPBB_1 PF03330.13 EGG11541.1 - 1.5e-06 28.1 0.9 6.1e-06 26.1 0.1 2.1 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGG11541.1 - 0.00019 21.0 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 Barwin family Pollen_allerg_1 PF01357.16 EGG11541.1 - 0.0015 18.2 0.1 0.0027 17.4 0.1 1.4 1 0 0 1 1 1 1 Pollen allergen Complex1_49kDa PF00346.14 EGG11542.1 - 1.6e-127 424.1 0.0 2.4e-127 423.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 EGG11542.1 - 0.0048 15.7 0.0 0.0069 15.2 0.0 1.2 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Antifungal_prot PF11402.3 EGG11543.1 - 2.8 8.2 8.5 23 5.2 1.0 3.0 2 1 0 2 2 2 0 Antifungal protein DUF202 PF02656.10 EGG11544.1 - 5.3e-19 68.2 0.1 1.3e-18 66.9 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF202) DUF3611 PF12263.3 EGG11544.1 - 0.084 12.2 1.9 0.16 11.3 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) HMG_box_2 PF09011.5 EGG11545.1 - 0.013 15.8 0.1 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.14 EGG11545.1 - 0.038 14.2 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box zf-CCHC_3 PF13917.1 EGG11546.1 - 0.0084 15.8 0.4 0.014 15.1 0.2 1.3 1 0 0 1 1 1 1 Zinc knuckle Copper-fist PF00649.13 EGG11546.1 - 0.034 13.3 0.2 0.068 12.3 0.1 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain zf-tcix PF14952.1 EGG11546.1 - 0.14 11.5 0.1 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding zf-CCHC_6 PF15288.1 EGG11546.1 - 0.22 11.2 1.9 0.5 10.0 1.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.20 EGG11547.1 - 3.6e-70 236.0 0.0 4.5e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11547.1 - 5.1e-33 114.2 0.0 6.9e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGG11547.1 - 7.9e-08 32.6 4.8 7.9e-08 32.6 3.3 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGG11547.1 - 0.0009 18.2 0.0 0.0031 16.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGG11547.1 - 0.042 12.8 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NADHdh-2_N PF12155.3 EGG11547.1 - 0.16 12.1 0.0 0.45 10.7 0.0 1.7 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal PIF1 PF05970.9 EGG11549.1 - 1.5e-24 86.6 0.0 2.8e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase FAR1 PF03101.10 EGG11549.1 - 9.2e-05 22.8 0.8 9.2e-05 22.8 0.5 1.7 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.6 EGG11549.1 - 0.00075 19.6 0.1 0.0018 18.4 0.1 1.6 1 0 0 1 1 1 1 Transcription factor AFT CD99L2 PF12301.3 EGG11550.1 - 0.07 12.8 1.7 0.11 12.1 1.2 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 IncA PF04156.9 EGG11550.1 - 2 7.9 10.2 13 5.3 7.1 2.1 1 1 0 1 1 1 0 IncA protein AAA_23 PF13476.1 EGG11550.1 - 3 8.1 9.7 6.6 7.0 6.7 1.4 1 1 0 1 1 1 0 AAA domain DUF947 PF06102.7 EGG11551.1 - 4.9e-16 59.0 23.7 1.9e-14 53.8 11.5 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF947) tRNA_lig_kinase PF08303.6 EGG11551.1 - 0.16 11.8 4.1 0.12 12.2 1.1 2.0 1 1 1 2 2 2 0 tRNA ligase kinase domain Trypan_PARP PF05887.6 EGG11551.1 - 0.21 11.4 4.8 0.4 10.4 3.4 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Alpha_kinase PF02816.13 EGG11556.1 - 4e-24 85.3 1.4 5.6e-24 84.8 1.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Helicase_C PF00271.26 EGG11557.1 - 1.5e-11 43.9 0.0 2.3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LPP20 PF02169.11 EGG11558.1 - 0.029 14.4 0.8 0.072 13.1 0.6 1.6 1 0 0 1 1 1 0 LPP20 lipoprotein Rho_N PF07498.7 EGG11561.1 - 2.5e-06 27.1 0.1 1.7e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain Desmo_N PF06771.6 EGG11562.1 - 0.21 11.5 1.1 4.2 7.3 0.0 2.7 3 0 0 3 3 3 0 Viral Desmoplakin N-terminus SOCS_box PF07525.11 EGG11562.1 - 1.4 8.7 4.5 6.6 6.6 0.1 3.4 4 0 0 4 4 4 0 SOCS box DUF4201 PF13870.1 EGG11563.1 - 0.07 12.5 0.6 0.11 11.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) ThiC-associated PF13667.1 EGG11565.1 - 0.13 11.8 0.1 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 ThiC-associated domain G6PD_C PF02781.11 EGG11567.1 - 2.5e-126 420.4 0.0 3.9e-126 419.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EGG11567.1 - 1.8e-60 204.3 0.0 5.3e-60 202.7 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain IBN_N PF03810.14 EGG11568.1 - 0.00018 21.3 0.1 0.0019 18.0 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EGG11568.1 - 0.025 14.4 3.3 0.54 10.1 0.1 4.5 4 2 0 4 4 4 0 Exportin 1-like protein Glyco_hydro_61 PF03443.9 EGG11568.1 - 0.21 11.3 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DUF1212 PF06738.7 EGG11569.1 - 1.4e-24 86.6 11.3 2e-24 86.1 1.7 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EGG11569.1 - 1.1e-12 48.0 8.8 1.1e-12 48.0 6.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) Tombus_P33 PF08500.5 EGG11569.1 - 0.043 13.5 2.9 12 5.6 2.0 2.4 2 0 0 2 2 2 0 Tombusvirus p33 Pkinase PF00069.20 EGG11571.1 - 5e-27 94.6 0.0 6.8e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11571.1 - 9.3e-17 60.9 0.0 1.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG11571.1 - 0.0076 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CFEM PF05730.6 EGG11573.1 - 2.3e-12 46.5 13.9 3.2e-12 46.1 9.6 1.2 1 0 0 1 1 1 1 CFEM domain Type_III_YscG PF09477.5 EGG11573.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TIL PF01826.12 EGG11573.1 - 7.7 6.7 10.2 10 6.3 6.1 1.8 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain ABC2_membrane PF01061.19 EGG11574.1 - 1.7e-33 115.5 24.3 1.7e-33 115.5 16.9 3.0 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 EGG11574.1 - 5.5e-23 81.7 0.0 3e-22 79.4 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EGG11574.1 - 5.8e-07 29.7 0.2 9.5e-05 22.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGG11574.1 - 0.0013 18.1 0.2 0.003 17.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGG11574.1 - 0.0035 16.5 0.0 0.0084 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGG11574.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGG11574.1 - 0.035 14.0 0.1 0.068 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EGG11574.1 - 0.042 13.9 0.0 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGG11574.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGG11574.1 - 0.15 11.4 0.2 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain SbcCD_C PF13558.1 EGG11574.1 - 0.16 11.9 0.1 1.8 8.5 0.0 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EGG11574.1 - 0.16 11.1 0.1 11 5.2 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.10 EGG11574.1 - 0.18 10.4 0.0 0.33 9.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 EGG11574.1 - 0.21 11.8 0.1 0.35 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain SKG6 PF08693.5 EGG11574.1 - 1.1 8.6 5.0 0.19 11.0 0.1 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain SNN_transmemb PF09049.5 EGG11574.1 - 2.3 7.9 8.1 0.19 11.4 2.0 1.9 2 0 0 2 2 1 0 Stannin transmembrane PXA PF02194.10 EGG11575.1 - 4e-30 104.7 0.0 1.7e-27 96.2 0.0 2.7 2 0 0 2 2 2 2 PXA domain Nexin_C PF08628.7 EGG11575.1 - 2.8e-24 85.3 0.0 1e-23 83.5 0.0 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EGG11575.1 - 1e-12 47.8 0.0 4.8e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 PX domain RGS PF00615.14 EGG11575.1 - 8.2e-07 29.1 0.1 1.9e-05 24.7 0.0 2.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain FTR1 PF03239.9 EGG11575.1 - 1.4 7.8 2.0 2.6 6.8 1.4 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family FlgD PF03963.9 EGG11577.1 - 0.064 13.3 0.7 0.17 12.0 0.5 1.6 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region Fasciclin PF02469.17 EGG11578.1 - 0.00065 19.7 0.0 0.0031 17.5 0.0 2.1 1 1 0 1 1 1 1 Fasciclin domain Mito_fiss_reg PF05308.6 EGG11580.1 - 4.7 6.5 15.6 8.7 5.6 10.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DEAD PF00270.24 EGG11581.1 - 7.9e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pentapeptide PF00805.17 EGG11581.1 - 0.13 11.5 0.2 0.3 10.3 0.1 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) BRE1 PF08647.6 EGG11582.1 - 0.022 14.7 9.3 0.036 14.0 6.5 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Pox_A30L_A26L PF06086.7 EGG11582.1 - 0.2 11.1 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein TFIIIC_sub6 PF10419.4 EGG11583.1 - 2.2e-11 43.0 0.0 3.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit Pkinase PF00069.20 EGG11584.1 - 1.5e-08 34.1 0.1 0.0013 17.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11584.1 - 1.1e-06 27.9 0.0 0.00087 18.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EGG11585.1 - 1.1e-15 57.5 0.0 1.6e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11585.1 - 0.0017 17.4 0.0 0.0058 15.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG11585.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF3759 PF12585.3 EGG11587.1 - 3.2e-20 71.8 9.2 3.5e-20 71.6 6.2 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3759) DUF678 PF05077.7 EGG11591.1 - 0.015 15.3 3.7 0.064 13.2 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Striatin PF08232.7 EGG11591.1 - 0.53 10.5 5.3 0.85 9.9 3.7 1.3 1 0 0 1 1 1 0 Striatin family Apt1 PF10351.4 EGG11591.1 - 1.7 7.3 7.1 2.1 7.0 4.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain U3_assoc_6 PF08640.6 EGG11592.1 - 1.6e-20 72.6 5.4 4.4e-20 71.2 0.7 3.4 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EGG11592.1 - 0.00045 20.6 0.0 2.2 9.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EGG11592.1 - 0.53 9.1 7.3 0.73 8.6 0.0 3.7 4 0 0 4 4 4 0 NRDE-2, necessary for RNA interference DUF2404 PF10296.4 EGG11594.1 - 2e-07 31.0 0.0 0.00019 21.4 0.0 2.3 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) HisG PF01634.13 EGG11595.1 - 5.9e-47 159.2 0.2 7.4e-47 158.9 0.1 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EGG11595.1 - 1.4e-24 85.8 0.0 5e-24 84.0 0.0 1.9 2 0 0 2 2 2 1 HisG, C-terminal domain adh_short_C2 PF13561.1 EGG11596.1 - 4.9e-28 98.5 1.0 5.8e-28 98.2 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGG11596.1 - 9.3e-22 77.7 0.9 1.4e-21 77.1 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG11596.1 - 2.9e-09 36.8 1.9 1.7e-08 34.3 1.3 1.9 1 1 0 1 1 1 1 KR domain MFS_1 PF07690.11 EGG11597.1 - 1.1e-47 162.4 39.5 1.8e-47 161.7 27.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EGG11597.1 - 5.6e-16 57.8 14.7 7.8e-16 57.3 10.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGG11597.1 - 1.6e-10 40.1 11.2 1.6e-10 40.1 7.8 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter LSM PF01423.17 EGG11598.1 - 7.5e-15 54.2 0.0 1.2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.20 EGG11599.1 - 1.5e-19 70.1 0.2 1.6e-19 70.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11599.1 - 2.1e-10 40.1 0.0 2.2e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG11599.1 - 0.053 13.2 0.2 0.22 11.2 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF726 PF05277.7 EGG11602.1 - 1.1e-118 396.1 3.9 1.5e-118 395.6 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EGG11602.1 - 0.00073 19.3 1.3 0.0028 17.4 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ribosomal_S8 PF00410.14 EGG11603.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S8 Dopey_N PF04118.9 EGG11604.1 - 1.9e-99 332.3 0.0 4.1e-99 331.2 0.0 1.6 1 0 0 1 1 1 1 Dopey, N-terminal LCM PF04072.9 EGG11605.1 - 1e-21 77.3 0.0 1.3e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Cupin_8 PF13621.1 EGG11606.1 - 5.4e-42 144.0 0.0 7.7e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGG11606.1 - 5e-10 39.1 0.0 1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 EGG11606.1 - 0.00048 20.3 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Abhydrolase_5 PF12695.2 EGG11609.1 - 8.3e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGG11609.1 - 0.00045 19.7 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EGG11609.1 - 0.01 15.0 0.0 0.029 13.6 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGG11609.1 - 0.019 14.8 0.0 0.19 11.5 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EGG11609.1 - 0.091 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_3 PF07859.8 EGG11609.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sec63 PF02889.11 EGG11612.1 - 3.8e-196 650.5 0.1 5.5e-110 367.4 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EGG11612.1 - 8.5e-52 175.0 0.1 1.7e-30 105.7 0.1 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EGG11612.1 - 9.2e-19 67.9 0.0 7.2e-10 38.9 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGG11612.1 - 8.3e-11 41.6 0.0 1.5e-07 31.2 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGG11612.1 - 1.1e-08 35.2 0.0 0.00067 19.8 0.0 3.9 3 1 0 3 3 3 2 AAA domain T2SE PF00437.15 EGG11612.1 - 0.0003 19.7 0.0 0.033 13.1 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein PhoH PF02562.11 EGG11612.1 - 0.00057 19.1 0.0 0.08 12.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activ_2 PF14532.1 EGG11612.1 - 0.061 13.3 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Cnd3 PF12719.2 EGG11613.1 - 1.2e-66 224.6 0.8 3e-65 220.1 0.0 3.0 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EGG11613.1 - 1.9e-10 40.8 1.3 0.00077 19.6 0.1 4.7 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EGG11613.1 - 1.1e-05 25.0 2.7 5.1 7.4 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EGG11613.1 - 0.058 13.8 0.5 6.1 7.4 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat Cnd1 PF12717.2 EGG11613.1 - 0.37 10.6 4.3 9.1 6.0 0.0 4.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Peptidase_M28 PF04389.12 EGG11615.1 - 3.7e-33 114.7 0.0 6.2e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Endosulfine PF04667.12 EGG11616.1 - 1.2e-19 70.0 0.0 1.9e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Peptidase_S49_N PF08496.5 EGG11617.1 - 0.45 10.2 9.0 1.1 9.0 6.2 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FLO_LFY PF01698.11 EGG11617.1 - 0.69 8.6 11.7 1.3 7.7 8.1 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein NARP1 PF12569.3 EGG11617.1 - 4.9 5.7 15.1 8.3 5.0 10.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pox_Ag35 PF03286.9 EGG11617.1 - 9.6 5.6 20.5 0.76 9.2 10.6 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein BRCA-2_OB1 PF09103.5 EGG11618.1 - 4.2e-21 74.8 0.0 8.7e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 EGG11618.1 - 1.1e-05 25.0 0.0 0.00094 18.7 0.1 2.3 2 0 0 2 2 2 2 BRCA2, helical DUF3275 PF11679.3 EGG11619.1 - 6.4 6.3 5.7 1 8.9 0.6 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3275) Alpha_kinase PF02816.13 EGG11620.1 - 2e-06 27.6 0.1 3.8e-06 26.6 0.1 1.4 1 1 0 1 1 1 1 Alpha-kinase family AMP-binding PF00501.23 EGG11621.1 - 3.1e-86 289.3 0.0 4.1e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF4292 PF14125.1 EGG11622.1 - 0.027 13.8 0.9 0.071 12.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4292) F-box PF00646.28 EGG11623.1 - 0.078 12.6 1.2 0.19 11.4 0.5 1.9 2 0 0 2 2 2 0 F-box domain Hydrolase_3 PF08282.7 EGG11624.1 - 2e-50 171.7 0.0 2.2e-50 171.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EGG11624.1 - 5.5e-10 38.9 0.0 5.8e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EGG11624.1 - 0.0007 20.0 0.0 0.02 15.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGG11624.1 - 0.0046 17.1 0.2 0.038 14.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CBM_2 PF00553.14 EGG11626.1 - 0.00036 20.5 17.9 0.0098 15.9 3.8 3.1 1 1 1 2 2 2 2 Cellulose binding domain Pkinase PF00069.20 EGG11628.1 - 4.3e-51 173.5 0.0 6e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11628.1 - 1.1e-29 103.2 0.0 1.7e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG11628.1 - 0.0027 16.7 0.0 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 EGG11628.1 - 0.003 16.4 0.2 0.0044 15.8 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase DUF4640 PF15480.1 EGG11628.1 - 0.062 12.8 0.2 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) APH PF01636.18 EGG11628.1 - 0.15 11.8 0.0 1.1 8.9 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1262 PF06880.6 EGG11629.1 - 0.064 13.5 1.7 0.62 10.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1262) Med15 PF09606.5 EGG11630.1 - 0.084 11.0 0.0 0.091 10.9 0.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DNA_topoisoIV PF00521.15 EGG11633.1 - 8.2e-129 430.1 0.0 3.4e-128 428.1 0.0 2.0 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EGG11633.1 - 2.4e-34 118.0 2.3 3.6e-34 117.4 0.3 2.2 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 EGG11633.1 - 2.2e-12 46.7 0.0 1.1e-11 44.5 0.0 2.3 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EGG11633.1 - 1.3e-10 40.9 0.2 4.2e-09 36.0 0.0 3.1 4 0 0 4 4 4 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGG11633.1 - 0.00027 20.6 0.5 0.00083 19.0 0.3 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_ligase_A_M PF01068.16 EGG11634.1 - 0.0019 17.5 0.2 0.0028 17.0 0.1 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain GRAM PF02893.15 EGG11635.1 - 1.3e-19 69.5 0.0 2e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 GRAM domain TatD_DNase PF01026.16 EGG11635.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 TatD related DNase NTF2 PF02136.15 EGG11636.1 - 6.5e-09 36.1 0.2 2.6e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EGG11636.1 - 2.5e-07 30.5 0.1 4e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Kinetocho_Slk19 PF12709.2 EGG11637.1 - 0.005 16.8 0.7 0.005 16.8 0.5 2.9 3 0 0 3 3 3 1 Central kinetochore-associated DUF874 PF05917.6 EGG11638.1 - 0.041 12.7 7.1 0.074 11.8 4.9 1.4 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF4440 PF14534.1 EGG11639.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Glyco_tran_28_C PF04101.11 EGG11640.1 - 5.3e-13 48.9 0.1 7.5e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Octopine_DH PF02317.12 EGG11641.1 - 2.2e-17 63.1 0.0 3.3e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain WD40 PF00400.27 EGG11642.1 - 1.4e-48 161.0 20.8 2.5e-08 33.4 0.1 12.4 12 0 0 12 12 12 11 WD domain, G-beta repeat Granulin PF00396.13 EGG11644.1 - 3.1 7.9 18.8 0.81 9.8 8.8 2.7 2 1 0 2 2 2 0 Granulin Hairy_orange PF07527.8 EGG11646.1 - 0.02 14.6 0.1 0.02 14.6 0.1 1.7 2 0 0 2 2 2 0 Hairy Orange Connexin_CCC PF10582.4 EGG11646.1 - 2.9 7.7 5.3 3.6 7.4 0.1 2.4 2 0 0 2 2 2 0 Gap junction channel protein cysteine-rich domain SF-assemblin PF06705.6 EGG11651.1 - 0.021 13.9 0.7 0.021 13.9 0.5 1.6 2 0 0 2 2 2 0 SF-assemblin/beta giardin Baculo_PEP_C PF04513.7 EGG11651.1 - 0.21 11.3 2.4 0.48 10.2 1.6 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 EGG11651.1 - 0.67 10.3 3.3 4.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Polysacc_deac_1 PF01522.16 EGG11652.1 - 3e-25 88.2 0.1 5.2e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase TspO_MBR PF03073.10 EGG11653.1 - 1.4e-44 151.1 9.3 1.7e-44 150.9 6.4 1.1 1 0 0 1 1 1 1 TspO/MBR family Glyco_hydro_31 PF01055.21 EGG11657.1 - 5.5e-112 374.8 2.4 1.1e-107 360.6 1.4 3.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGG11657.1 - 5.8e-11 42.0 0.1 1.8e-10 40.5 0.1 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like TPR_11 PF13414.1 EGG11658.1 - 0.0011 18.5 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 TPR repeat FMO-like PF00743.14 EGG11659.1 - 1.6e-28 99.2 0.0 1.1e-20 73.3 0.0 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGG11659.1 - 1.3e-12 48.1 0.0 2.1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGG11659.1 - 3.2e-10 39.4 0.0 7e-08 31.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGG11659.1 - 9e-06 25.5 0.0 0.0074 16.0 0.0 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.12 EGG11659.1 - 2.8e-05 23.3 0.0 0.00086 18.4 0.0 2.7 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.9 EGG11659.1 - 0.00015 21.7 0.0 0.00024 21.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGG11659.1 - 0.00022 21.1 0.0 0.00058 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Semialdhyde_dh PF01118.19 EGG11659.1 - 0.0095 16.2 0.0 5.5 7.3 0.0 2.4 2 0 0 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain Tafi-CsgC PF10610.4 EGG11661.1 - 0.027 14.3 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Thin aggregative fimbriae synthesis protein DUF2659 PF10858.3 EGG11662.1 - 0.62 9.4 2.0 0.38 10.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2659) SHS2_FTSA PF02491.15 EGG11663.1 - 0.019 14.8 0.0 0.066 13.1 0.0 1.9 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA FAA_hydrolase PF01557.13 EGG11665.1 - 8.4e-56 188.8 0.0 9.6e-56 188.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family STE3 PF02076.10 EGG11666.1 - 5.1e-43 147.1 18.2 6.3e-43 146.8 12.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor Prothymosin PF03247.9 EGG11668.1 - 0.0014 18.7 12.4 0.0014 18.7 8.6 2.9 3 0 0 3 3 3 1 Prothymosin/parathymosin family DUF3530 PF12048.3 EGG11668.1 - 0.13 11.2 3.9 0.27 10.1 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Cu-oxidase_3 PF07732.10 EGG11669.1 - 2.9e-41 139.8 3.9 4.5e-40 136.0 0.9 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EGG11669.1 - 4.9e-31 107.7 0.3 1.4e-26 93.2 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG11669.1 - 6e-29 100.3 8.2 2e-25 88.8 0.3 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGG11670.1 - 8.7e-42 141.5 2.3 2.2e-40 137.0 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG11670.1 - 3.1e-32 110.9 5.8 1.3e-26 92.7 0.2 3.9 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EGG11670.1 - 2.5e-25 89.2 0.1 2.5e-24 85.9 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase YrhC PF14143.1 EGG11670.1 - 0.18 11.8 0.0 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 YrhC-like protein Cu-oxidase_3 PF07732.10 EGG11671.1 - 4.6e-40 136.0 0.1 4.6e-40 136.0 0.1 2.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG11671.1 - 3.3e-30 104.4 4.9 4.1e-26 91.1 0.1 2.7 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EGG11671.1 - 1.1e-29 103.4 0.2 2e-25 89.5 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase polyprenyl_synt PF00348.12 EGG11672.1 - 9.7e-66 221.2 0.0 3.7e-64 216.0 0.0 2.0 1 1 0 1 1 1 1 Polyprenyl synthetase Lipase_3 PF01764.20 EGG11673.1 - 4.9e-14 52.1 0.0 1.2e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGG11673.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L9_N PF01281.14 EGG11674.1 - 1.6e-07 30.4 0.0 2.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain USP7_C2 PF14533.1 EGG11674.1 - 0.0017 17.8 1.2 0.003 17.0 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal Pkinase PF00069.20 EGG11675.1 - 3e-62 210.1 0.0 4.2e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11675.1 - 6.5e-28 97.5 0.0 1e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG11675.1 - 9.1e-06 24.8 0.0 2.7e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGG11675.1 - 0.011 15.5 0.1 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA_12 PF13087.1 EGG11677.1 - 2.7e-62 209.6 0.0 3.5e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGG11677.1 - 2.3e-34 119.0 0.1 3.2e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EGG11677.1 - 6.2e-06 25.9 0.0 0.018 14.5 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EGG11677.1 - 0.044 13.9 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain NTP_transferase PF00483.18 EGG11679.1 - 1.3e-24 86.8 0.0 1.7e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EGG11679.1 - 5.6e-09 35.0 5.6 4.2e-07 29.1 0.3 4.1 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EGG11679.1 - 0.00013 22.0 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Formyl_trans_N PF00551.14 EGG11680.1 - 1.7e-14 53.8 0.0 2.6e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 Formyl transferase FA_desaturase PF00487.19 EGG11681.1 - 4.3e-09 36.1 23.4 4.3e-09 36.1 16.2 1.8 1 1 1 2 2 2 1 Fatty acid desaturase SH3_1 PF00018.23 EGG11682.1 - 2.3e-10 39.6 0.0 4.2e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGG11682.1 - 2.9e-09 36.2 0.0 5.6e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EGG11682.1 - 1.8e-08 33.8 0.0 3.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_4 PF06347.8 EGG11682.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Glucan_synthase PF02364.10 EGG11683.1 - 4.2e-55 187.0 2.4 3.4e-34 117.8 0.0 4.0 1 1 2 3 3 3 3 1,3-beta-glucan synthase component Glucan_synthase PF02364.10 EGG11684.1 - 1.3e-41 142.4 9.5 4e-17 61.4 0.5 3.0 1 1 2 3 3 3 3 1,3-beta-glucan synthase component OTU PF02338.14 EGG11685.1 - 0.0067 17.0 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Zn_clus PF00172.13 EGG11687.1 - 0.42 10.5 5.7 4.9 7.1 0.1 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Syntaxin PF00804.20 EGG11691.1 - 0.012 15.7 2.6 0.016 15.3 1.8 1.2 1 0 0 1 1 1 0 Syntaxin DUF3987 PF13148.1 EGG11691.1 - 0.019 13.5 0.3 0.024 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Enkurin PF13864.1 EGG11691.1 - 0.022 14.9 2.2 0.041 14.0 1.6 1.5 1 1 0 1 1 1 0 Calmodulin-binding DAGK_cat PF00781.19 EGG11691.1 - 0.031 13.7 0.4 0.093 12.1 0.1 1.8 1 1 1 2 2 2 0 Diacylglycerol kinase catalytic domain DUF3573 PF12097.3 EGG11691.1 - 0.054 12.1 0.2 0.06 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HALZ PF02183.13 EGG11691.1 - 0.059 13.0 0.5 0.27 10.9 0.0 2.2 2 1 1 3 3 3 0 Homeobox associated leucine zipper CCDC-167 PF15188.1 EGG11691.1 - 0.072 13.0 3.6 0.21 11.5 2.5 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Syntaxin-6_N PF09177.6 EGG11691.1 - 0.095 13.1 2.3 0.19 12.1 1.6 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Phage_Gp19 PF09355.5 EGG11691.1 - 0.13 12.0 1.0 0.27 11.0 0.2 1.7 1 1 1 2 2 2 0 Phage protein Gp19/Gp15/Gp42 ISG65-75 PF11727.3 EGG11691.1 - 0.15 11.0 1.6 0.18 10.8 1.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein COG5 PF10392.4 EGG11691.1 - 0.19 11.6 3.2 0.32 10.9 2.2 1.3 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Fmp27_WPPW PF10359.4 EGG11691.1 - 0.27 9.5 3.5 0.33 9.2 2.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TBPIP PF07106.8 EGG11691.1 - 0.51 9.8 7.1 2.7 7.5 4.9 1.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EGG11691.1 - 0.7 9.4 6.5 1 8.9 4.3 1.4 1 1 0 1 1 1 0 IncA protein PCRF PF03462.13 EGG11691.1 - 0.86 9.3 3.3 1.2 8.8 0.9 2.0 1 1 1 2 2 2 0 PCRF domain DnaG_DnaB_bind PF08278.6 EGG11691.1 - 1.3 9.2 4.5 1.3 9.2 1.5 2.0 2 1 1 3 3 3 0 DNA primase DnaG DnaB-binding Val_tRNA-synt_C PF10458.4 EGG11691.1 - 2.5 8.2 7.4 30 4.7 0.1 3.4 3 1 1 4 4 4 0 Valyl tRNA synthetase tRNA binding arm SseC PF04888.7 EGG11692.1 - 0.011 15.1 3.2 0.012 14.9 2.2 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Paf1 PF03985.8 EGG11692.1 - 0.014 14.1 1.6 0.016 13.9 1.1 1.1 1 0 0 1 1 1 0 Paf1 FliD_C PF07195.7 EGG11692.1 - 0.015 14.5 1.3 0.021 14.1 0.9 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus COG5 PF10392.4 EGG11692.1 - 0.02 14.8 2.0 0.038 13.9 1.4 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF342 PF03961.8 EGG11692.1 - 0.037 12.4 4.0 0.042 12.2 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Sipho_Gp157 PF05565.6 EGG11692.1 - 0.038 13.5 1.6 0.06 12.9 1.1 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 V_ATPase_I PF01496.14 EGG11692.1 - 0.045 11.6 4.3 0.049 11.5 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EGG11692.1 - 0.071 12.1 9.5 0.084 11.9 6.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ING PF12998.2 EGG11692.1 - 0.099 12.9 7.3 0.081 13.2 3.7 1.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4509 PF14970.1 EGG11692.1 - 0.13 11.9 2.9 0.16 11.6 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Surfac_D-trimer PF09006.6 EGG11692.1 - 0.14 11.9 0.1 2.6 7.8 0.0 2.3 1 1 1 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation TMPIT PF07851.8 EGG11692.1 - 0.14 11.2 1.9 0.17 10.9 1.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.10 EGG11692.1 - 0.18 11.3 4.3 0.09 12.2 0.9 2.0 1 1 1 2 2 2 0 Septum formation initiator CDC37_N PF03234.9 EGG11692.1 - 0.32 11.2 6.2 0.27 11.5 3.6 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Bacillus_HBL PF05791.6 EGG11692.1 - 0.35 10.2 6.9 0.39 10.0 3.0 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Exonuc_VII_L PF02601.10 EGG11692.1 - 0.37 9.9 7.2 0.44 9.6 5.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mnd1 PF03962.10 EGG11692.1 - 0.4 10.3 7.2 0.5 9.9 5.0 1.2 1 0 0 1 1 1 0 Mnd1 family RRP7 PF12923.2 EGG11692.1 - 0.66 10.0 6.1 3.9 7.5 4.2 2.0 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) GrpE PF01025.14 EGG11692.1 - 0.73 9.3 4.9 0.63 9.5 2.8 1.4 1 1 0 1 1 1 0 GrpE Seryl_tRNA_N PF02403.17 EGG11692.1 - 1.1 9.2 6.9 1.1 9.3 4.2 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Macoilin PF09726.4 EGG11692.1 - 1.2 7.3 7.7 1.3 7.1 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 EGG11692.1 - 1.4 8.5 12.6 6.3 6.3 8.9 1.8 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 EGG11692.1 - 1.9 7.3 8.2 2.2 7.1 5.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin PF00804.20 EGG11692.1 - 2.6 8.2 8.7 1.4 9.1 4.0 2.0 1 1 1 2 2 2 0 Syntaxin PABP PF00658.13 EGG11693.1 - 8.1e-10 38.2 0.0 9.3e-10 38.0 0.0 1.0 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain PTCB-BRCT PF12738.2 EGG11694.1 - 7.7e-11 41.6 0.0 3.2e-09 36.5 0.0 2.4 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EGG11694.1 - 1.1e-05 25.4 0.0 0.0014 18.7 0.0 2.6 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RNB PF00773.14 EGG11695.1 - 0.056 12.7 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 RNB domain LRR_4 PF12799.2 EGG11698.1 - 0.068 12.8 0.9 0.84 9.3 0.5 3.0 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) DnaJ PF00226.26 EGG11700.1 - 7.8e-13 47.9 0.2 1.7e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 DnaJ domain ADAM_spacer1 PF05986.9 EGG11700.1 - 0.02 14.7 0.0 0.051 13.4 0.0 1.8 1 1 1 2 2 2 0 ADAM-TS Spacer 1 Adenylate_cycl PF01295.13 EGG11700.1 - 0.12 10.6 0.4 0.15 10.2 0.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I DinB_2 PF12867.2 EGG11701.1 - 6.1e-07 29.8 1.5 8.3e-07 29.3 1.1 1.2 1 0 0 1 1 1 1 DinB superfamily Cnl2_NKP2 PF09447.5 EGG11701.1 - 0.2 11.3 0.7 5.8 6.6 0.1 2.3 2 0 0 2 2 2 0 Cnl2/NKP2 family protein SNF2_N PF00176.18 EGG11702.1 - 2.7e-78 262.7 0.3 4.7e-78 262.0 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EGG11702.1 - 5.7e-41 138.9 3.4 5.7e-41 138.9 2.4 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 EGG11702.1 - 2.5e-19 69.7 1.3 2.5e-19 69.7 0.9 3.4 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EGG11702.1 - 1.1e-14 53.9 0.0 3.6e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG11702.1 - 5.8e-09 36.0 0.8 1.1e-07 31.8 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGG11702.1 - 5.4e-05 22.7 0.1 0.00026 20.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EGG11702.1 - 0.0014 18.1 0.0 0.0035 16.7 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 AAA_14 PF13173.1 EGG11702.1 - 0.032 14.1 0.0 0.13 12.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGG11702.1 - 0.042 13.9 0.0 0.2 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain Thymidylat_synt PF00303.14 EGG11703.1 - 7.2e-109 362.9 0.0 8.1e-109 362.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Vps39_1 PF10366.4 EGG11705.1 - 2.4e-29 101.5 0.1 2.4e-29 101.5 0.1 3.1 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EGG11705.1 - 8.9e-19 67.6 0.3 2.9e-18 66.0 0.2 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 TPR_8 PF13181.1 EGG11705.1 - 0.96 9.3 3.9 25 4.9 0.1 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3237 PF11578.3 EGG11706.1 - 0.007 15.6 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ATP-synt_C PF00137.16 EGG11709.1 - 2.7e-28 97.6 17.5 6.5e-16 57.9 4.2 2.3 2 0 0 2 2 2 2 ATP synthase subunit C AA_permease_2 PF13520.1 EGG11710.1 - 0.0035 15.9 9.2 0.0045 15.5 6.4 1.1 1 0 0 1 1 1 1 Amino acid permease Period_C PF12114.3 EGG11710.1 - 0.0074 15.9 5.5 0.011 15.3 3.8 1.2 1 0 0 1 1 1 1 Period protein 2/3C-terminal region POX PF07526.6 EGG11710.1 - 0.032 14.4 1.4 0.051 13.7 1.0 1.3 1 0 0 1 1 1 0 Associated with HOX Ketoacyl-synt_2 PF13723.1 EGG11711.1 - 0.19 10.9 0.0 0.19 10.9 0.0 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Glycos_transf_3 PF00591.16 EGG11714.1 - 2e-74 250.1 0.0 2.3e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain UBN2_3 PF14244.1 EGG11716.1 - 0.08 12.4 0.0 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type NPV_P10 PF05531.7 EGG11719.1 - 0.0029 17.8 2.1 0.0071 16.5 1.5 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein LPP PF04728.8 EGG11719.1 - 0.024 14.4 0.1 0.063 13.0 0.1 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Rhodanese PF00581.15 EGG11720.1 - 9.2e-10 38.8 0.1 1.9e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain ABM PF03992.11 EGG11722.1 - 8.1e-12 45.0 0.0 9.6e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase HSP20 PF00011.16 EGG11723.1 - 4.3e-09 36.1 0.0 4.5e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF21 PF01595.15 EGG11724.1 - 0.49 9.6 4.0 0.8 8.9 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF21 PigN PF04987.9 EGG11726.1 - 3.2e-116 388.5 29.7 4.3e-116 388.1 20.6 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EGG11726.1 - 3.3e-11 43.1 0.2 4.9e-09 35.9 0.0 2.7 2 1 1 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGG11726.1 - 0.00037 19.7 0.0 0.00098 18.3 0.0 1.6 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 EGG11726.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily Peptidase_U4 PF03419.8 EGG11726.1 - 0.17 10.9 4.1 0.4 9.6 2.9 1.6 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF2369 PF10179.4 EGG11726.1 - 0.25 10.4 0.0 0.4 9.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) UreD PF01774.12 EGG11727.1 - 5.6e-36 123.9 0.0 7.3e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 UreD urease accessory protein TPR_11 PF13414.1 EGG11728.1 - 7.3e-22 76.7 4.2 3.3e-11 42.6 0.3 3.5 2 1 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 EGG11728.1 - 1.7e-19 68.0 5.8 6.8e-07 28.7 0.1 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGG11728.1 - 1e-18 66.0 5.6 5.9e-09 35.1 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGG11728.1 - 4.5e-17 60.7 1.2 0.00017 21.4 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGG11728.1 - 3.3e-12 45.9 2.5 3.7e-05 23.9 0.0 5.3 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGG11728.1 - 1e-10 41.9 0.7 4e-08 33.7 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGG11728.1 - 1.7e-09 36.7 1.1 0.00014 21.4 0.0 4.4 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGG11728.1 - 2.2e-09 37.0 0.4 6.9e-06 25.9 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGG11728.1 - 4.4e-07 30.1 0.4 0.021 15.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGG11728.1 - 5.8e-05 22.5 0.0 0.0032 17.1 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGG11728.1 - 0.0027 17.5 1.4 0.0088 15.8 0.0 2.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGG11728.1 - 0.0042 17.4 0.1 0.8 10.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EGG11728.1 - 0.021 14.6 0.0 1.7 8.6 0.0 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EGG11728.1 - 0.032 14.1 0.1 0.15 12.0 0.1 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat TRC8_N PF13705.1 EGG11729.1 - 0.067 11.7 0.0 0.076 11.5 0.0 1.0 1 0 0 1 1 1 0 TRC8 N-terminal domain ABC_transp_aux PF09822.4 EGG11729.1 - 0.14 11.5 0.0 1.4 8.2 0.0 1.9 2 0 0 2 2 2 0 ABC-type uncharacterized transport system MT-A70 PF05063.9 EGG11730.1 - 1.1e-54 184.5 0.0 2.3e-54 183.5 0.0 1.5 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 EGG11730.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CoaE PF01121.15 EGG11732.1 - 1.4e-55 187.5 0.0 1.6e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 EGG11732.1 - 2.7e-08 34.1 0.6 1e-07 32.2 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EGG11732.1 - 5.5e-05 23.9 0.2 0.00013 22.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGG11732.1 - 0.027 14.3 0.0 0.084 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain PMP22_Claudin PF00822.15 EGG11732.1 - 0.037 13.6 0.3 6.5 6.3 0.0 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF4284 PF14112.1 EGG11732.1 - 0.04 14.4 0.1 0.14 12.6 0.0 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4284) SKI PF01202.17 EGG11732.1 - 0.056 13.3 0.2 8.4 6.2 0.1 2.3 2 1 0 2 2 2 0 Shikimate kinase Protoglobin PF11563.3 EGG11735.1 - 2e-05 24.3 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protoglobin ParA PF10609.4 EGG11738.1 - 1.3e-33 114.7 0.4 2.5e-33 113.7 0.3 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGG11738.1 - 3.9e-17 62.3 0.0 5.2e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGG11738.1 - 1.7e-07 31.3 0.0 4.5e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EGG11738.1 - 3.3e-05 23.0 0.6 8.6e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EGG11738.1 - 5.6e-05 22.3 2.4 0.00038 19.5 0.2 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.1 EGG11738.1 - 0.00062 19.4 0.9 0.27 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain Fer4_NifH PF00142.13 EGG11738.1 - 0.015 14.4 0.0 0.042 13.0 0.1 1.6 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 EGG11738.1 - 0.1 11.9 0.2 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EGG11738.1 - 0.2 11.4 0.8 14 5.4 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain Fe-S_biosyn PF01521.15 EGG11739.1 - 1.9e-13 50.3 0.0 3.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PS_Dcarbxylase PF02666.10 EGG11740.1 - 1.5e-51 174.5 0.0 2.3e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EGG11740.1 - 6.7e-25 86.7 0.0 9.4e-14 51.0 0.0 2.9 2 1 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EGG11740.1 - 0.00082 19.4 0.1 0.0044 17.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EGG11740.1 - 0.0051 16.6 0.7 0.082 12.8 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 EGG11740.1 - 0.0066 15.6 1.5 0.054 12.8 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 EGG11740.1 - 0.012 14.9 0.1 0.064 12.6 0.0 2.4 2 0 0 2 2 2 0 EF hand tRNA-synt_2d PF01409.15 EGG11742.1 - 3.4e-45 154.1 0.2 2.8e-25 88.9 0.0 2.2 1 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EGG11742.1 - 8.9e-25 86.6 0.0 2.1e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF2404 PF10296.4 EGG11743.1 - 2.2e-07 30.9 0.0 0.00019 21.4 0.0 2.3 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) AAR2 PF05282.6 EGG11744.1 - 1.3e-48 165.8 5.0 1.5e-48 165.5 3.5 1.0 1 0 0 1 1 1 1 AAR2 protein IL6 PF00489.12 EGG11744.1 - 0.076 12.6 0.3 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family Mo25 PF08569.6 EGG11745.1 - 2.3e-55 187.9 9.0 2.5e-55 187.8 6.3 1.0 1 0 0 1 1 1 1 Mo25-like DUF2228 PF10228.4 EGG11745.1 - 0.033 13.7 1.0 0.04 13.4 0.7 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DDE_Tnp_IS240 PF13610.1 EGG11747.1 - 0.1 12.5 0.2 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 DDE domain Haemolytic PF01809.13 EGG11748.1 - 0.12 11.9 2.4 0.22 11.1 1.7 1.3 1 0 0 1 1 1 0 Haemolytic domain zf-CCHC PF00098.18 EGG11750.1 - 0.0044 16.8 2.0 0.0091 15.8 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 EGG11750.1 - 0.0055 16.4 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 EGG11750.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein DHHW PF14286.1 EGG11750.1 - 0.084 12.1 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 DHHW protein Ribosomal_S3_C PF00189.15 EGG11751.1 - 9e-15 54.6 0.0 1.8e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EGG11751.1 - 3.7e-14 52.0 0.1 6.4e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 KH domain DUF3734 PF12536.3 EGG11752.1 - 0.01 15.9 0.5 0.032 14.3 0.3 1.9 1 0 0 1 1 1 0 Patatin phospholipase UPF0181 PF03701.9 EGG11752.1 - 0.038 13.2 0.1 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Dicty_REP PF05086.7 EGG11753.1 - 0.36 8.5 3.6 0.42 8.3 2.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GRP PF07172.6 EGG11754.1 - 0.054 13.9 0.0 0.078 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycine rich protein family KRE9 PF05390.6 EGG11754.1 - 0.16 12.3 1.3 0.19 12.0 0.9 1.2 1 0 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 TTL PF03133.10 EGG11756.1 - 3.4e-60 203.4 0.5 4.4e-60 203.1 0.4 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EGG11756.1 - 5.7e-06 25.3 0.0 0.00053 18.8 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EGG11756.1 - 0.031 14.0 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain CENP-B_dimeris PF09026.5 EGG11756.1 - 0.038 14.2 0.2 0.08 13.1 0.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LEAP-2 PF07359.6 EGG11757.1 - 0.06 13.0 0.7 0.1 12.2 0.4 1.5 1 1 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Alpha_GJ PF03229.8 EGG11757.1 - 0.35 11.1 3.8 0.57 10.5 2.6 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J COesterase PF00135.23 EGG11758.1 - 8.4e-76 255.7 0.0 1.3e-75 255.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF963 PF06131.6 EGG11758.1 - 8.5 5.7 26.4 2 7.7 15.2 2.3 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF846 PF05832.7 EGG11760.1 - 1e-50 171.1 10.9 1.4e-50 170.7 7.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Pex14_N PF04695.8 EGG11760.1 - 0.085 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BPD_transp_1 PF00528.17 EGG11760.1 - 3.4 7.1 10.6 0.17 11.3 1.8 2.1 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component p450 PF00067.17 EGG11762.1 - 6.3e-52 176.6 0.1 8.2e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EGG11763.1 - 1.1e-36 126.3 0.0 1.3e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11763.1 - 4.9e-13 48.7 0.0 6.9e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG11763.1 - 3.8e-06 26.8 0.4 0.022 14.4 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 EGG11765.1 - 7.4e-20 71.1 0.0 1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11765.1 - 3e-11 42.8 0.0 4e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.26 EGG11767.1 - 7.5e-17 60.8 0.0 2.4e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Apc3 PF12895.2 EGG11767.1 - 0.00069 19.7 8.5 0.0041 17.2 0.0 3.5 4 2 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EGG11767.1 - 0.0014 18.9 0.2 3.8 7.9 0.0 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGG11767.1 - 0.0034 16.9 1.7 0.044 13.4 0.0 3.0 3 1 1 4 4 4 1 TPR repeat DUF309 PF03745.9 EGG11767.1 - 0.04 13.3 0.1 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF309) DUF4441 PF14536.1 EGG11768.1 - 0.021 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) JmjC PF02373.17 EGG11771.1 - 1.8e-11 44.2 0.1 1.8e-11 44.2 0.0 2.5 3 0 0 3 3 3 1 JmjC domain, hydroxylase Hap4_Hap_bind PF10297.4 EGG11772.1 - 0.00027 20.6 5.4 0.00088 19.0 3.7 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Tho2 PF11262.3 EGG11772.1 - 0.009 15.0 1.5 0.015 14.3 1.0 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 IncA PF04156.9 EGG11772.1 - 0.018 14.6 0.2 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 EGG11772.1 - 0.018 14.2 3.5 0.033 13.3 2.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fmp27_WPPW PF10359.4 EGG11772.1 - 0.023 13.1 2.2 0.034 12.5 1.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TSC22 PF01166.13 EGG11772.1 - 0.024 14.5 1.1 0.075 13.0 0.1 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family Phage_lysis PF03245.8 EGG11772.1 - 0.063 13.2 1.7 0.081 12.9 0.2 1.8 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein bZIP_1 PF00170.16 EGG11772.1 - 0.32 10.9 8.1 0.21 11.5 2.1 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF2894 PF11445.3 EGG11772.1 - 0.57 10.4 5.3 0.26 11.5 1.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2894) DUF904 PF06005.7 EGG11772.1 - 1.4 9.2 6.5 3.1 8.1 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Nucleoside_tran PF01733.13 EGG11773.1 - 0.15 11.2 0.1 0.27 10.3 0.1 1.3 1 0 0 1 1 1 0 Nucleoside transporter HTH_21 PF13276.1 EGG11774.1 - 5.2e-05 23.1 1.5 0.0041 17.1 0.3 3.2 3 1 0 3 3 3 1 HTH-like domain HTH_32 PF13565.1 EGG11774.1 - 0.00019 22.1 3.3 0.034 14.9 0.0 3.9 4 0 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EGG11774.1 - 1.4 8.4 4.3 2.4 7.7 0.0 2.9 4 0 0 4 4 4 0 Helix-turn-helix domain Fumble PF03630.9 EGG11776.1 - 8.3e-113 376.6 0.2 5.3e-89 298.4 0.1 3.1 3 0 0 3 3 3 3 Fumble Methyltransf_3 PF01596.12 EGG11777.1 - 1.5e-16 60.0 0.0 4e-16 58.6 0.0 1.6 2 1 0 2 2 2 1 O-methyltransferase Methyltransf_18 PF12847.2 EGG11777.1 - 0.00043 20.8 0.0 0.00084 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG11777.1 - 0.0077 16.2 0.0 0.017 15.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EGG11777.1 - 0.02 14.3 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 EGG11777.1 - 0.033 15.0 0.0 0.13 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain ThiF PF00899.16 EGG11779.1 - 3e-10 40.0 0.1 7.6e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 ThiF family Fibrillarin PF01269.12 EGG11779.1 - 1.4e-05 24.1 0.1 2.3e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Fibrillarin UBACT PF02134.16 EGG11779.1 - 2e-05 24.0 0.0 4.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein DUF3221 PF11518.3 EGG11779.1 - 0.0091 15.6 2.9 0.22 11.1 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3221) Methyltransf_3 PF01596.12 EGG11780.1 - 2.7e-33 114.7 0.0 4.7e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EGG11780.1 - 1.4e-07 32.3 0.0 3.1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG11780.1 - 1e-06 29.2 0.0 2.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG11780.1 - 1.5e-05 24.9 0.0 5.7e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Abhydrolase_2 PF02230.11 EGG11781.1 - 1.9e-11 43.8 0.0 2.9e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGG11781.1 - 0.00067 19.4 0.0 0.00097 18.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG11781.1 - 0.0017 18.2 0.1 0.0038 17.1 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EGG11782.1 - 3.6e-20 71.9 27.8 1.4e-12 47.0 0.7 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG11782.1 - 4.1e-05 22.3 14.1 0.0001 21.0 0.2 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 EGG11782.1 - 0.0028 16.1 0.1 0.0028 16.1 0.1 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein DUF3455 PF11937.3 EGG11783.1 - 1.1e-18 67.7 0.0 1.4e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2372 PF10178.4 EGG11784.1 - 0.013 15.6 0.1 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2372) Cu-oxidase PF00394.17 EGG11786.1 - 1.7e-42 145.0 1.2 1.5e-36 125.7 0.3 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGG11786.1 - 3e-37 127.2 10.9 5.8e-36 123.0 0.2 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGG11786.1 - 4e-34 116.8 7.3 2.8e-30 104.4 0.5 3.8 4 0 0 4 4 4 2 Multicopper oxidase NP1-WLL PF11733.3 EGG11787.1 - 0.02 15.1 2.5 0.02 15.1 1.7 2.0 2 0 0 2 2 2 0 Non-capsid protein NP1 Asp PF00026.18 EGG11789.1 - 6.8e-46 156.9 4.1 2.3e-45 155.2 2.8 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG11789.1 - 5.6e-06 26.4 0.4 0.00012 22.1 0.3 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGG11789.1 - 0.0025 18.2 3.0 0.2 12.1 0.2 3.5 4 0 0 4 4 4 1 Aspartyl protease Ten1 PF12658.2 EGG11791.1 - 0.093 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Telomere capping, CST complex subunit zf-ISL3 PF14690.1 EGG11793.1 - 0.038 14.0 0.1 6.2 6.9 0.0 2.8 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF4328 PF14219.1 EGG11796.1 - 0.048 12.9 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) PP-binding PF00550.20 EGG11798.1 - 1e-14 54.5 0.3 1.5e-14 54.0 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EGG11798.1 - 2.5e-05 24.2 0.1 3.7e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier PCI PF01399.22 EGG11799.1 - 1.9e-18 66.7 1.2 4.6e-18 65.4 0.5 2.0 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EGG11799.1 - 1.1e-09 38.1 1.2 2.8e-09 36.9 0.8 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_11 PF13414.1 EGG11799.1 - 0.084 12.5 0.3 0.7 9.5 0.1 2.6 2 0 0 2 2 2 0 TPR repeat zf-C2H2_4 PF13894.1 EGG11800.1 - 0.2 12.0 9.0 0.61 10.5 0.7 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGG11800.1 - 0.4 11.1 12.0 0.48 10.8 1.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Glyco_transf_8 PF01501.15 EGG11801.1 - 3.7e-25 88.6 0.3 4.7e-25 88.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EGG11801.1 - 0.00071 19.0 0.5 0.0054 16.1 0.2 1.9 2 0 0 2 2 2 1 Mannosyltransferase putative FAM75 PF14650.1 EGG11802.1 - 0.71 9.1 5.2 0.79 9.0 3.6 1.0 1 0 0 1 1 1 0 FAM75 family F-box PF00646.28 EGG11805.1 - 4.4 7.0 7.3 3.9 7.2 0.1 3.8 5 0 0 5 5 5 0 F-box domain GCM PF03615.10 EGG11806.1 - 0.03 13.9 0.1 0.074 12.6 0.1 1.6 1 0 0 1 1 1 0 GCM motif protein DASH_Hsk3 PF08227.6 EGG11809.1 - 0.0097 16.0 4.1 0.018 15.1 2.9 1.5 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Pro-kuma_activ PF09286.6 EGG11812.1 - 7.8e-31 107.0 0.0 1.4e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGG11812.1 - 1.5e-07 30.8 0.1 2.5e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Subtilase family DPBB_1 PF03330.13 EGG11813.1 - 1.1e-07 31.7 0.0 8.8e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGG11813.1 - 8.5e-07 28.6 0.1 1.2e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 Barwin family DUF3185 PF11381.3 EGG11814.1 - 0.51 10.1 5.8 0.68 9.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) MFS_1 PF07690.11 EGG11815.1 - 6.3e-26 90.9 33.9 9e-24 83.8 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily G-gamma PF00631.17 EGG11817.1 - 4.5e-25 87.1 0.0 5.1e-25 86.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain RE_NgoPII PF09521.5 EGG11820.1 - 0.058 12.1 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 NgoPII restriction endonuclease V-ATPase_G PF03179.10 EGG11820.1 - 0.16 12.2 10.2 0.28 11.5 7.1 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit APG6 PF04111.7 EGG11820.1 - 4 6.3 8.8 5.6 5.9 6.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1770 PF08589.5 EGG11822.1 - 0.00041 20.9 0.4 0.0016 18.9 0.3 2.3 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) CS PF04969.11 EGG11823.1 - 2.1e-08 34.5 0.7 4.8e-07 30.2 0.5 2.7 1 1 0 1 1 1 1 CS domain Cobalamin_bind PF01122.14 EGG11824.1 - 0.013 14.0 2.2 0.015 13.9 1.5 1.1 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein Fib_alpha PF08702.5 EGG11824.1 - 2.4 8.2 9.1 2.8 8.0 6.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family G-alpha PF00503.15 EGG11827.1 - 6.1e-11 41.6 0.0 6.3e-11 41.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Nucleoplasmin PF03066.10 EGG11828.1 - 1.1 8.7 5.8 2.3 7.7 4.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin Myticin-prepro PF10690.4 EGG11829.1 - 0.014 15.4 2.5 0.014 15.4 1.7 1.5 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel PFK PF00365.15 EGG11830.1 - 8e-25 87.3 0.0 1.1e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase FAM216B PF15107.1 EGG11830.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 FAM216B protein family zf-CHCC PF10276.4 EGG11831.1 - 6.8e-18 64.2 2.4 8.2e-18 63.9 0.8 1.8 2 0 0 2 2 2 1 Zinc-finger domain WD40 PF00400.27 EGG11834.1 - 2e-55 182.7 19.6 3.8e-09 36.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EGG11834.1 - 4.9e-05 23.1 0.0 0.15 11.7 0.0 2.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EGG11834.1 - 0.055 12.9 0.1 0.16 11.3 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain Nucleoporin_N PF08801.6 EGG11834.1 - 0.075 11.7 0.4 17 4.0 0.0 2.9 3 0 0 3 3 3 0 Nup133 N terminal like GPI-anchored PF10342.4 EGG11836.1 - 5.1e-15 55.7 3.7 5.1e-15 55.7 2.5 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HA2 PF04408.18 EGG11837.1 - 3.3e-17 62.3 0.0 8.5e-17 61.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGG11837.1 - 7.6e-12 44.9 0.1 1.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 EGG11837.1 - 3.8e-11 43.3 0.0 0.00047 20.6 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.24 EGG11837.1 - 1.9e-05 24.2 0.0 4.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 EGG11837.1 - 0.0017 18.0 0.1 0.0085 15.8 0.1 2.2 1 1 0 1 1 1 1 Part of AAA domain OB_NTP_bind PF07717.11 EGG11837.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold ResIII PF04851.10 EGG11837.1 - 0.061 13.1 0.0 0.35 10.6 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SRP54 PF00448.17 EGG11837.1 - 0.17 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Cellulase PF00150.13 EGG11838.1 - 4.7e-11 42.4 0.5 7.8e-11 41.6 0.0 1.6 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) PUB PF09409.5 EGG11841.1 - 2e-13 49.9 1.5 4.8e-13 48.6 0.1 2.1 2 0 0 2 2 2 1 PUB domain NumbF PF06311.7 EGG11841.1 - 0.14 12.2 0.7 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 NUMB domain Homoserine_dh PF00742.14 EGG11842.1 - 5.2e-50 169.6 0.0 8.1e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EGG11842.1 - 5e-10 39.8 0.0 9.4e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GST_N_3 PF13417.1 EGG11843.1 - 1.4e-09 38.0 0.0 3.2e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGG11843.1 - 2.6e-07 30.7 0.0 6.6e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGG11843.1 - 1.5e-06 28.0 0.0 3.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGG11843.1 - 0.00029 20.6 0.0 0.00054 19.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGG11843.1 - 0.01 15.7 0.0 0.11 12.4 0.0 2.5 2 1 1 3 3 3 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGG11843.1 - 0.059 13.8 0.0 0.16 12.4 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Saccharop_dh PF03435.13 EGG11847.1 - 2.1e-20 73.0 0.0 2.9e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EGG11847.1 - 0.096 12.1 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family A_deaminase PF00962.17 EGG11848.1 - 1.6e-32 112.7 0.0 2.1e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase TP_methylase PF00590.15 EGG11848.1 - 0.032 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases A_deaminase PF00962.17 EGG11849.1 - 7.2e-28 97.4 0.1 8.3e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase TP_methylase PF00590.15 EGG11849.1 - 0.008 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Vps5 PF09325.5 EGG11851.1 - 2.6e-05 23.5 0.4 0.0066 15.7 0.0 2.1 1 1 1 2 2 2 2 Vps5 C terminal like OTCace_N PF02729.16 EGG11851.1 - 0.016 14.8 0.1 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Allexi_40kDa PF05549.6 EGG11851.1 - 0.016 14.4 0.6 0.02 14.1 0.4 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Myb_DNA-bind_4 PF13837.1 EGG11853.1 - 0.0053 16.8 0.5 0.012 15.7 0.4 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EGG11853.1 - 0.027 14.6 1.5 0.079 13.1 1.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Vps5 PF09325.5 EGG11853.1 - 0.043 13.0 2.6 0.13 11.4 0.2 2.3 2 0 0 2 2 2 0 Vps5 C terminal like FAM165 PF14981.1 EGG11853.1 - 0.12 11.8 0.6 15 5.1 0.0 2.7 2 0 0 2 2 2 0 FAM165 family DUF573 PF04504.9 EGG11853.1 - 0.29 11.4 2.7 0.21 11.8 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Kelch_4 PF13418.1 EGG11854.1 - 1.5e-46 155.8 7.9 3.5e-10 39.4 0.0 6.1 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EGG11854.1 - 1.5e-42 142.8 3.2 7.2e-09 35.5 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EGG11854.1 - 1.8e-35 120.3 5.9 5.4e-07 29.4 0.3 6.1 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EGG11854.1 - 2.1e-35 120.0 1.3 4.1e-05 23.0 0.0 6.1 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EGG11854.1 - 4.7e-34 115.1 7.6 4.2e-05 23.5 0.0 6.2 2 2 4 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EGG11854.1 - 3.8e-30 102.4 8.3 6.7e-05 22.4 0.0 6.2 6 0 0 6 6 6 6 Kelch motif PQQ_3 PF13570.1 EGG11854.1 - 0.52 10.6 5.4 58 4.1 0.0 4.8 6 0 0 6 6 6 0 PQQ-like domain RRM_1 PF00076.17 EGG11856.1 - 6.7e-17 60.8 0.0 8.2e-17 60.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG11856.1 - 6.7e-12 45.2 0.0 8.9e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG11856.1 - 5.2e-06 26.2 0.0 7.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EGG11857.1 - 3.5e-22 78.7 0.0 1.2e-13 50.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11857.1 - 1.2e-07 31.1 0.7 0.00083 18.5 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGG11857.1 - 0.027 14.1 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGG11857.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family dUTPase PF00692.14 EGG11859.1 - 1.6e-27 95.4 0.0 1.8e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 dUTPase MAM33 PF02330.11 EGG11860.1 - 1.2e-31 110.0 3.1 1.7e-31 109.5 2.2 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein Pkinase PF00069.20 EGG11861.1 - 1.1e-73 247.5 0.0 1.3e-73 247.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11861.1 - 2.4e-33 115.2 0.0 6.7e-33 113.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG11861.1 - 0.0057 15.6 0.0 0.013 14.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGG11861.1 - 0.011 15.4 0.1 0.022 14.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGG11861.1 - 0.087 11.8 0.1 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CBFB_NFYA PF02045.10 EGG11863.1 - 5.4e-26 90.9 4.9 7.9e-26 90.3 3.4 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Serglycin PF04360.7 EGG11865.1 - 0.028 14.1 2.2 0.077 12.7 1.5 1.7 1 0 0 1 1 1 0 Serglycin DUF3021 PF11457.3 EGG11866.1 - 0.17 11.8 2.8 0.3 10.9 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) SEA PF01390.15 EGG11868.1 - 0.045 13.4 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 SEA domain EVC2_like PF12297.3 EGG11868.1 - 0.089 11.4 0.2 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein BCLP PF12304.3 EGG11868.1 - 0.62 9.4 8.1 0.097 12.0 2.7 1.9 2 1 0 2 2 2 0 Beta-casein like protein DUF2678 PF10856.3 EGG11868.1 - 2.9 7.6 11.0 0.2 11.4 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) DUF4064 PF13273.1 EGG11868.1 - 4.4 7.4 16.9 1 9.4 7.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) IBR PF01485.16 EGG11869.1 - 9.2e-16 57.4 41.5 1.1e-10 41.2 4.5 4.2 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EGG11869.1 - 0.097 12.5 0.0 0.097 12.5 0.0 4.6 2 2 1 3 3 3 0 Ring finger domain Saccharop_dh PF03435.13 EGG11870.1 - 7.3e-19 67.9 0.0 1.1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Saccharop_dh PF03435.13 EGG11873.1 - 1.1e-13 50.9 0.0 1.5e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase SpoIIIAC PF06686.6 EGG11873.1 - 0.56 10.0 5.4 1.3 8.9 3.7 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AC/AD protein family Pkinase PF00069.20 EGG11874.1 - 4.5e-67 225.9 0.0 9.1e-67 224.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG11874.1 - 1.9e-36 125.4 0.0 2.9e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EGG11874.1 - 2.9e-20 72.0 1.1 1.4e-10 40.9 0.2 2.7 2 0 0 2 2 2 2 POLO box duplicated region Vps16_N PF04841.8 EGG11876.1 - 1.3e-69 234.7 0.0 2.7e-69 233.6 0.0 1.5 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EGG11876.1 - 5.2e-52 176.7 0.2 2.6e-36 125.2 0.9 2.3 2 0 0 2 2 2 2 Vps16, C-terminal region DUF296 PF03479.10 EGG11878.1 - 0.041 13.4 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF296) Afi1 PF07792.7 EGG11879.1 - 6.3e-44 149.5 0.1 1.1e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EGG11879.1 - 1.4e-34 118.2 0.0 5.5e-34 116.2 0.0 2.0 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.4 EGG11879.1 - 1e-09 37.3 0.0 8.8e-05 21.1 0.0 3.3 3 1 0 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.4 EGG11879.1 - 7.6e-05 22.1 0.0 0.019 14.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Sec23_trunk PF04811.10 EGG11885.1 - 2.4e-71 239.9 0.0 4e-71 239.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGG11885.1 - 4.1e-23 80.7 0.1 1.1e-22 79.4 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGG11885.1 - 1e-17 64.4 0.0 5.2e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGG11885.1 - 1.3e-16 59.8 5.9 2.4e-16 58.9 4.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGG11885.1 - 1.5e-08 34.2 0.0 3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 EGG11885.1 - 0.0098 15.7 0.0 0.0098 15.7 0.0 1.9 2 0 0 2 2 2 1 WW domain TEX12 PF15219.1 EGG11885.1 - 0.22 11.4 0.1 0.59 10.1 0.1 1.7 1 0 0 1 1 1 0 Testis-expressed 12 WD40 PF00400.27 EGG11886.1 - 1e-68 224.9 25.6 4.5e-13 48.5 0.0 7.8 8 0 0 8 8 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EGG11886.1 - 3e-20 72.1 8.3 4.5e-20 71.6 5.8 1.3 1 0 0 1 1 1 1 Tup N-terminal PD40 PF07676.7 EGG11886.1 - 8.4e-06 25.3 2.0 0.51 10.0 0.0 5.4 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EGG11886.1 - 3.7e-05 22.9 0.5 0.69 8.9 0.0 4.1 2 1 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EGG11886.1 - 0.00034 18.8 4.5 0.27 9.3 0.1 4.1 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGG11886.1 - 0.0031 16.3 0.4 2.4 6.8 0.0 3.6 1 1 2 3 3 3 1 Nup133 N terminal like CENP-Q PF13094.1 EGG11886.1 - 0.0041 17.1 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EGG11886.1 - 0.0054 16.3 4.4 0.0085 15.7 3.1 1.2 1 0 0 1 1 1 1 IncA protein DivIVA PF05103.8 EGG11886.1 - 0.011 15.7 2.2 0.019 14.9 1.5 1.2 1 0 0 1 1 1 0 DivIVA protein HALZ PF02183.13 EGG11886.1 - 0.014 15.1 7.0 0.051 13.3 0.0 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper ADIP PF11559.3 EGG11886.1 - 0.017 15.0 8.1 0.027 14.3 5.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MAD PF05557.8 EGG11886.1 - 0.017 13.2 3.8 0.022 12.8 2.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Cytochrom_D1 PF02239.11 EGG11886.1 - 0.018 13.3 0.4 2.1 6.5 0.0 2.6 2 1 0 2 2 2 0 Cytochrome D1 heme domain DUF972 PF06156.8 EGG11886.1 - 0.019 15.3 0.2 0.039 14.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.6 EGG11886.1 - 0.041 12.5 4.1 0.054 12.1 2.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF812 PF05667.6 EGG11886.1 - 0.042 12.3 1.0 0.063 11.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) EzrA PF06160.7 EGG11886.1 - 0.053 11.6 1.4 0.074 11.2 0.9 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3312 PF11768.3 EGG11886.1 - 0.057 11.6 0.0 4.4 5.4 0.0 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3312) Jnk-SapK_ap_N PF09744.4 EGG11886.1 - 0.072 13.0 4.6 0.12 12.3 3.2 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4201 PF13870.1 EGG11886.1 - 0.075 12.4 5.7 0.12 11.7 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) TMPIT PF07851.8 EGG11886.1 - 0.077 12.0 3.7 0.11 11.5 2.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Prp19 PF08606.6 EGG11886.1 - 0.14 11.8 0.8 0.47 10.2 0.2 2.1 2 1 1 3 3 2 0 Prp19/Pso4-like TPR_MLP1_2 PF07926.7 EGG11886.1 - 0.15 11.8 6.7 0.36 10.5 4.6 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein VIT1 PF01988.14 EGG11886.1 - 0.17 11.3 0.2 0.38 10.2 0.1 1.5 1 0 0 1 1 1 0 VIT family Myosin_tail_1 PF01576.14 EGG11886.1 - 0.19 9.3 4.4 0.26 8.9 3.1 1.0 1 0 0 1 1 1 0 Myosin tail PspA_IM30 PF04012.7 EGG11886.1 - 0.26 10.6 3.5 0.38 10.0 2.4 1.1 1 0 0 1 1 1 0 PspA/IM30 family Tropomyosin_1 PF12718.2 EGG11886.1 - 0.28 11.0 5.2 0.44 10.3 3.6 1.2 1 0 0 1 1 1 0 Tropomyosin like Proteasome_A_N PF10584.4 EGG11886.1 - 0.34 10.2 5.4 58 3.1 0.1 4.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Leu_zip PF15294.1 EGG11886.1 - 0.37 9.8 5.2 0.53 9.3 3.6 1.1 1 0 0 1 1 1 0 Leucine zipper APG6 PF04111.7 EGG11886.1 - 0.42 9.5 5.6 0.62 9.0 3.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EGG11886.1 - 0.48 10.2 7.6 0.82 9.5 5.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YscO PF07321.7 EGG11886.1 - 0.48 10.2 8.5 0.76 9.5 5.9 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO Tmemb_cc2 PF10267.4 EGG11886.1 - 0.59 8.6 4.6 0.97 7.9 3.2 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein GAS PF13851.1 EGG11886.1 - 1.1 8.4 6.3 1.7 7.8 4.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.3 EGG11886.1 - 1.6 7.9 5.2 2.3 7.3 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3584 PF12128.3 EGG11886.1 - 2.1 5.5 6.0 2.9 5.0 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PIP5K PF01504.13 EGG11887.1 - 7.2e-85 284.1 0.0 9.5e-85 283.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF605 PF04652.11 EGG11889.1 - 3.9 6.7 14.1 5.3 6.3 9.8 1.2 1 0 0 1 1 1 0 Vta1 like CCDC142 PF14923.1 EGG11890.1 - 0.022 13.1 1.6 0.042 12.1 1.1 1.5 1 0 0 1 1 1 0 Coiled-coil protein 142 Omega_Repress PF07764.6 EGG11890.1 - 0.097 13.0 0.0 2.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Omega Transcriptional Repressor GCM PF03615.10 EGG11894.1 - 0.017 14.7 1.1 0.048 13.2 0.2 2.1 2 0 0 2 2 2 0 GCM motif protein Nop14 PF04147.7 EGG11894.1 - 9.3 4.0 27.9 13 3.5 19.4 1.1 1 0 0 1 1 1 0 Nop14-like family Sad1_UNC PF07738.8 EGG11900.1 - 3.1e-26 91.7 0.0 4e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SlyX PF04102.7 EGG11902.1 - 0.031 14.6 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 SlyX Med21 PF11221.3 EGG11902.1 - 0.37 10.7 0.1 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 Subunit 21 of Mediator complex DUF3049 PF11250.3 EGG11904.1 - 0.14 11.9 0.4 11 5.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3049) XPG_N PF00752.12 EGG11906.1 - 3e-25 88.3 0.0 5.3e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EGG11906.1 - 1.6e-21 76.1 0.0 3.3e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EGG11906.1 - 0.00099 18.6 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.12 EGG11906.1 - 0.0015 18.2 0.0 0.0042 16.8 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat 5_3_exonuc PF01367.15 EGG11906.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TPR_1 PF00515.23 EGG11906.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGG11906.1 - 0.15 12.7 0.7 2.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3398 PF11878.3 EGG11908.1 - 0.38 10.6 11.3 21 5.0 0.2 4.6 1 1 5 6 6 6 0 Domain of unknown function (DUF3398) zf-RING_2 PF13639.1 EGG11909.1 - 0.00014 21.5 3.1 0.00037 20.2 2.1 1.8 1 0 0 1 1 1 1 Ring finger domain EcsC PF12787.2 EGG11909.1 - 0.076 12.3 0.9 0.64 9.3 0.3 2.1 2 0 0 2 2 2 0 EcsC protein family LSM PF01423.17 EGG11910.1 - 1.9e-15 56.1 0.4 2.6e-15 55.6 0.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGG11910.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain ATP-synt_E PF05680.7 EGG11911.1 - 0.26 11.2 3.3 0.34 10.8 0.7 2.1 2 0 0 2 2 2 0 ATP synthase E chain BUD22 PF09073.5 EGG11911.1 - 1.2 8.1 18.0 0.047 12.7 6.4 2.0 2 0 0 2 2 2 0 BUD22 PBP_sp32 PF07222.7 EGG11911.1 - 3.7 6.6 7.4 5.7 6.0 5.1 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC27 PF09507.5 EGG11913.1 - 4.4 6.4 19.0 5 6.2 13.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP PF00230.15 EGG11914.1 - 7.6e-30 104.0 3.7 3.4e-21 75.7 0.5 2.1 2 0 0 2 2 2 2 Major intrinsic protein CN_hydrolase PF00795.17 EGG11915.1 - 4.6e-13 48.9 0.0 7.2e-13 48.3 0.0 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DPM3 PF08285.6 EGG11916.1 - 0.31 10.9 1.2 22 4.9 0.0 2.5 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2934 PF11154.3 EGG11916.1 - 3.7 6.9 9.9 2.5 7.5 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) DUF2849 PF11011.3 EGG11916.1 - 5.1 7.4 7.4 6.1 7.1 1.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2849) Aldedh PF00171.17 EGG11917.1 - 8.7e-176 584.7 0.0 9.8e-176 584.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGG11917.1 - 4.8e-05 22.2 0.0 7.4e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EGG11917.1 - 0.00041 19.6 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) DUF667 PF05018.8 EGG11918.1 - 3e-19 68.9 0.5 1.1e-18 67.1 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF667) Baculo_PEP_C PF04513.7 EGG11919.1 - 0.04 13.7 2.3 0.11 12.3 0.3 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3437 PF11919.3 EGG11922.1 - 9.4e-27 92.5 0.1 3.4e-26 90.7 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 EGG11922.1 - 7.9e-07 29.2 2.8 3.4e-05 24.0 0.1 4.2 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.17 EGG11922.1 - 2.2e-05 24.1 5.9 0.00069 19.4 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EGG11922.1 - 2.9e-05 24.4 2.0 0.001 19.4 0.0 4.4 4 0 0 4 4 4 1 HEAT-like repeat Sec1 PF00995.18 EGG11923.1 - 1e-111 374.3 0.0 1.2e-111 374.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family YqhR PF11085.3 EGG11923.1 - 0.18 11.3 0.1 0.53 9.7 0.0 1.8 2 0 0 2 2 2 0 Conserved membrane protein YqhR Vma12 PF11712.3 EGG11924.1 - 9.4e-17 61.0 0.0 1.2e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase MFS_1 PF07690.11 EGG11925.1 - 5.1e-28 97.8 21.2 5.1e-28 97.8 14.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily ATP-synt_8 PF00895.15 EGG11925.1 - 4.1 7.6 6.2 22 5.3 0.3 3.1 3 0 0 3 3 3 0 ATP synthase protein 8 DUF1228 PF06779.9 EGG11925.1 - 4.2 7.4 8.4 0.62 10.1 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 EGG11926.1 - 1.2e-35 122.8 31.5 1.2e-35 122.8 21.8 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EGG11927.1 - 4.8e-35 120.9 26.0 4.8e-35 120.9 18.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Coatomer_WDAD PF04053.9 EGG11928.1 - 2.4e-146 488.0 0.1 5.3e-146 486.9 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 EGG11928.1 - 4.6e-100 335.1 0.0 6.9e-100 334.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EGG11928.1 - 6.8e-54 177.9 8.1 4.2e-10 39.1 0.3 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EGG11928.1 - 0.00022 19.5 5.6 0.0059 14.8 0.2 3.7 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Clathrin PF00637.15 EGG11928.1 - 0.039 13.5 0.1 0.38 10.3 0.0 2.4 3 0 0 3 3 3 0 Region in Clathrin and VPS Nucleoporin_N PF08801.6 EGG11928.1 - 0.051 12.3 2.8 1.9 7.1 0.0 3.8 3 1 1 4 4 4 0 Nup133 N terminal like Ribosomal_L35p PF01632.14 EGG11929.1 - 3.6e-06 26.7 2.8 6.7e-06 25.9 1.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L35 Cmc1 PF08583.5 EGG11930.1 - 4.7e-11 42.2 0.1 5.6e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like MAAL_C PF07476.6 EGG11930.1 - 0.041 12.8 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus NDUF_B7 PF05676.8 EGG11930.1 - 0.046 13.1 0.4 0.064 12.6 0.3 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF1409 PF07197.7 EGG11930.1 - 0.067 13.2 1.5 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) GCK PF07802.6 EGG11930.1 - 0.12 12.5 0.3 0.74 9.9 0.1 1.9 1 1 1 2 2 2 0 GCK domain 3HCDH_N PF02737.13 EGG11932.1 - 0.08 12.5 0.3 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Melibiase PF02065.13 EGG11933.1 - 6.7e-08 31.6 0.0 9e-07 27.9 0.0 2.1 2 0 0 2 2 2 1 Melibiase Glyco_hydro_31 PF01055.21 EGG11933.1 - 0.0008 18.3 0.0 0.0012 17.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 MFS_1 PF07690.11 EGG11934.1 - 1.4e-34 119.3 23.3 1.4e-34 119.3 16.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG11934.1 - 1.5e-05 23.7 19.0 3e-05 22.7 13.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EGG11934.1 - 0.00016 20.0 0.6 0.00025 19.4 0.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGG11934.1 - 0.0013 17.1 22.7 0.0016 16.9 1.8 3.3 1 1 0 3 3 3 3 MFS/sugar transport protein F-box-like PF12937.2 EGG11935.1 - 0.057 13.1 0.5 0.45 10.2 0.0 2.7 2 1 0 2 2 2 0 F-box-like DUF383 PF04063.9 EGG11936.1 - 0.034 13.6 0.5 0.084 12.4 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF383) YL1 PF05764.8 EGG11936.1 - 0.56 9.7 10.7 0.89 9.1 7.4 1.3 1 1 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 EGG11936.1 - 0.73 7.7 4.5 0.71 7.8 3.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Usp PF00582.21 EGG11937.1 - 1.2e-08 35.2 0.1 3.3e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Universal stress protein family DUF1556 PF07590.6 EGG11938.1 - 0.054 13.7 2.0 6 7.1 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1556) FF PF01846.14 EGG11939.1 - 2.6e-23 81.7 3.9 1.1e-10 41.3 0.0 5.0 4 0 0 4 4 4 3 FF domain WW PF00397.21 EGG11939.1 - 6.4e-13 48.3 21.9 1.1e-06 28.3 2.0 3.2 3 0 0 3 3 3 2 WW domain CKS PF01111.14 EGG11940.1 - 2.9e-34 116.7 0.5 3.7e-34 116.3 0.3 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF3844 PF12955.2 EGG11941.1 - 0.077 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) HMG_CoA_synt_N PF01154.12 EGG11943.1 - 4.7e-86 286.7 0.0 8.9e-86 285.8 0.0 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 EGG11943.1 - 6.6e-84 281.7 0.9 8.2e-84 281.4 0.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal VLPT PF07122.6 EGG11944.1 - 0.011 15.3 0.5 0.021 14.4 0.3 1.5 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) GPCR_chapero_1 PF11904.3 EGG11946.1 - 0.039 13.1 0.0 0.04 13.0 0.0 1.0 1 0 0 1 1 1 0 GPCR-chaperone Carb_kinase PF01256.12 EGG11947.1 - 0.03 13.6 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate kinase PX PF00787.19 EGG11947.1 - 0.097 12.4 1.0 0.15 11.8 0.3 1.6 1 1 1 2 2 2 0 PX domain ERCC4 PF02732.10 EGG11949.1 - 6.1e-26 90.8 0.4 1.8e-25 89.3 0.4 1.7 2 0 0 2 2 2 1 ERCC4 domain HHH_8 PF14716.1 EGG11949.1 - 2e-06 27.8 0.0 5.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Rad9 PF04139.8 EGG11950.1 - 8.2e-37 126.6 2.5 1.4e-36 125.8 1.7 1.4 1 0 0 1 1 1 1 Rad9 Flavodoxin_2 PF02525.12 EGG11950.1 - 0.031 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin-like fold FKS1_dom1 PF14288.1 EGG11955.1 - 9.2e-14 51.3 0.1 6.4e-07 29.3 0.0 2.3 1 1 1 2 2 2 2 1,3-beta-glucan synthase subunit FKS1, domain-1 zf-HC5HC2H_2 PF13832.1 EGG11957.1 - 9.5e-33 112.5 11.3 3.7e-32 110.5 4.4 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGG11957.1 - 2.1e-24 85.4 3.8 2.1e-24 85.4 2.6 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EGG11957.1 - 1.5e-18 67.5 0.2 2.1e-18 67.0 0.2 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.1 EGG11957.1 - 1.3e-15 56.4 2.6 1.3e-15 56.4 1.8 3.9 6 0 0 6 6 6 2 PHD-finger PHD PF00628.24 EGG11957.1 - 1.2e-11 44.1 5.3 1.2e-11 44.1 3.7 3.4 3 1 1 4 4 4 2 PHD-finger zf-PHD-like PF15446.1 EGG11957.1 - 0.00086 18.6 1.8 0.00086 18.6 1.2 2.8 2 1 0 3 3 3 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EGG11957.1 - 0.0021 17.7 0.2 0.0021 17.7 0.1 3.4 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EGG11957.1 - 0.013 15.2 2.4 0.013 15.2 1.7 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EGG11957.1 - 0.02 14.8 7.6 0.02 14.8 5.3 3.2 3 1 0 3 3 3 0 RING-like domain FYVE_2 PF02318.11 EGG11957.1 - 0.029 14.2 1.2 0.029 14.2 0.9 2.6 2 1 1 3 3 3 0 FYVE-type zinc finger DUF2039 PF10217.4 EGG11957.1 - 0.042 13.8 4.3 0.042 13.8 3.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2039) Carn_acyltransf PF00755.15 EGG11957.1 - 0.061 11.4 0.0 0.082 10.9 0.0 1.1 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase zf-UDP PF14569.1 EGG11957.1 - 2.7 7.8 10.7 2 8.2 3.2 2.5 2 1 0 2 2 2 0 Zinc-binding RING-finger Bromodomain PF00439.20 EGG11958.1 - 1.8e-19 69.4 0.3 2e-19 69.2 0.2 1.1 1 0 0 1 1 1 1 Bromodomain CAF-1_p150 PF11600.3 EGG11959.1 - 1.6 8.0 27.4 0.72 9.1 5.0 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RRM_6 PF14259.1 EGG11960.1 - 7.6e-05 22.6 0.0 0.0003 20.7 0.0 2.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.4 EGG11960.1 - 0.00041 18.7 0.1 0.00041 18.7 0.0 3.2 1 1 1 3 3 3 1 Transmembrane protein ubiquitin PF00240.18 EGG11961.1 - 8.7e-12 44.2 0.1 1.9e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EGG11961.1 - 7.7e-05 22.3 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EGG11961.1 - 0.0012 18.7 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGG11961.1 - 0.082 13.1 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PITH PF06201.8 EGG11963.1 - 2.3e-22 79.4 0.0 3e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 PITH domain Metallophos PF00149.23 EGG11964.1 - 1e-09 38.1 1.8 1.8e-09 37.3 1.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase B12-binding PF02310.14 EGG11964.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain EamA PF00892.15 EGG11965.1 - 6.4e-10 39.1 22.8 2.5e-07 30.7 1.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF914 PF06027.7 EGG11965.1 - 3.9e-06 25.9 7.8 4.6e-06 25.7 5.1 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EGG11965.1 - 0.00044 19.2 9.2 0.00054 18.9 6.4 1.1 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EGG11965.1 - 0.00076 19.6 0.9 0.00076 19.6 0.7 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 EGG11965.1 - 0.01 15.5 20.1 0.24 11.0 1.9 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF2340 PF10209.4 EGG11966.1 - 6.6e-39 132.8 0.7 7.7e-39 132.6 0.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) ATP12 PF07542.6 EGG11968.1 - 0.016 15.1 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 ATP12 chaperone protein DUF2520 PF10728.4 EGG11968.1 - 0.099 12.0 0.1 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) UPF0184 PF03670.8 EGG11968.1 - 0.79 9.9 6.0 1.1 9.5 4.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) AhpC-TSA_2 PF13911.1 EGG11969.1 - 5.5e-09 35.9 0.0 1.7e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGG11969.1 - 0.015 14.9 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA family BING4CT PF08149.6 EGG11970.1 - 1.1e-36 124.1 0.7 1.5e-34 117.3 0.0 3.2 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.27 EGG11970.1 - 5e-09 35.7 4.3 8e-07 28.7 0.1 5.1 7 0 0 7 7 7 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EGG11970.1 - 0.069 11.9 0.0 0.17 10.6 0.0 1.5 2 0 0 2 2 2 0 Coatomer WD associated region Mog1 PF04603.7 EGG11971.1 - 8.3e-26 90.6 0.2 1.4e-25 89.8 0.1 1.4 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Ribosomal_S19 PF00203.16 EGG11972.1 - 3.2e-34 116.3 0.3 5e-34 115.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 EGG11972.1 - 5.1e-05 23.1 0.0 6.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Flagellar assembly protein FliH Effector_1 PF04518.7 EGG11974.1 - 0.015 14.3 0.5 0.015 14.3 0.4 1.4 2 0 0 2 2 2 0 Effector from type III secretion system DUF3732 PF12532.3 EGG11974.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) PTS_2-RNA PF01885.11 EGG11975.1 - 6.7e-59 198.3 0.0 8.2e-59 198.0 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family TFIID-31kDa PF02291.10 EGG11976.1 - 6.7e-39 132.6 0.0 8.3e-39 132.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 EGG11976.1 - 2.4e-06 27.1 0.0 4.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 EGG11976.1 - 0.0063 16.6 0.1 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_30kDa PF03540.8 EGG11976.1 - 0.023 14.5 0.2 0.05 13.4 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit CENP-S PF15630.1 EGG11976.1 - 0.027 14.6 0.1 0.047 13.8 0.1 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S DUF4565 PF15127.1 EGG11976.1 - 0.067 13.5 0.0 0.22 11.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4565) CENP-T PF15511.1 EGG11976.1 - 0.82 8.8 7.4 0.48 9.6 1.6 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Histone PF00125.19 EGG11977.1 - 3.5e-26 91.1 0.0 4.4e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGG11977.1 - 1.2e-05 25.2 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1777 PF08648.7 EGG11978.1 - 2.9 7.5 35.4 1.9 8.1 13.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) DDRGK PF09756.4 EGG11978.1 - 7.6 5.8 31.2 0.063 12.6 6.0 2.1 1 1 1 2 2 2 0 DDRGK domain Histone PF00125.19 EGG11979.1 - 1e-22 79.9 0.1 1.4e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGG11979.1 - 1.6e-05 24.8 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EGG11979.1 - 0.0032 17.6 0.0 0.0048 17.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Con-6 PF10346.4 EGG11980.1 - 1.2e-25 88.5 2.0 8.4e-13 47.5 0.2 2.1 2 0 0 2 2 2 2 Conidiation protein 6 Toxin_52 PF15605.1 EGG11980.1 - 0.001 18.9 1.3 0.37 10.7 0.1 2.2 1 1 1 2 2 2 2 Putative toxin 52 DUF1539 PF07560.6 EGG11980.1 - 0.0015 18.4 0.7 0.83 9.5 0.1 2.1 1 1 1 2 2 2 2 Domain of Unknown Function (DUF1539) Limkain-b1 PF11608.3 EGG11980.1 - 0.11 12.2 0.3 0.16 11.7 0.2 1.4 1 1 0 1 1 1 0 Limkain b1 Cauli_AT PF03233.8 EGG11980.1 - 0.14 11.9 0.8 0.2 11.3 0.3 1.3 1 1 0 1 1 1 0 Aphid transmission protein OSCP PF00213.13 EGG11980.1 - 0.19 11.6 0.9 4.8 7.0 0.1 2.1 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit SpoIIIAH PF12685.2 EGG11980.1 - 0.3 10.5 5.1 1.4 8.3 0.7 2.2 1 1 0 2 2 2 0 SpoIIIAH-like protein Sterol_MT_C PF08498.5 EGG11981.1 - 2.7e-22 78.4 0.2 4.3e-22 77.8 0.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 EGG11981.1 - 1.1e-14 54.3 0.0 1.6e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG11981.1 - 9.9e-12 45.1 0.0 2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGG11981.1 - 3.2e-09 36.2 0.1 4.1e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGG11981.1 - 4.1e-09 36.3 0.0 7.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG11981.1 - 1.4e-08 35.3 0.1 5e-08 33.4 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG11981.1 - 7.1e-07 29.6 0.2 2.3e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG11981.1 - 1.6e-06 28.3 0.0 3.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGG11981.1 - 1.7e-06 28.0 0.0 4.9e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EGG11981.1 - 0.0002 20.9 0.2 0.00034 20.2 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.13 EGG11981.1 - 0.0044 16.1 0.0 0.0075 15.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 EGG11981.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase PCMT PF01135.14 EGG11981.1 - 0.067 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Opi1 PF08618.5 EGG11982.1 - 0.011 14.7 0.8 0.013 14.3 0.6 1.0 1 0 0 1 1 1 0 Transcription factor Opi1 RPN7 PF10602.4 EGG11983.1 - 2.8e-46 157.0 1.6 2.8e-46 157.0 1.1 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EGG11983.1 - 3e-15 56.3 1.7 3.6e-15 56.1 0.2 1.9 2 0 0 2 2 2 1 PCI domain Clr2 PF10383.4 EGG11984.1 - 1.8e-09 37.6 0.1 5.3e-09 36.2 0.1 1.8 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 DUF679 PF05078.7 EGG11984.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF679) PWWP PF00855.12 EGG11984.1 - 0.14 12.3 5.4 0.38 10.9 0.0 3.7 3 1 0 3 3 3 0 PWWP domain DNA_primase_S PF01896.14 EGG11985.1 - 3.8e-52 175.9 0.1 7.1e-52 175.0 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF823 PF05689.6 EGG11986.1 - 0.062 12.6 0.1 0.077 12.3 0.1 1.1 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) Sec23_trunk PF04811.10 EGG11987.1 - 2.2e-75 253.1 0.0 3.5e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGG11987.1 - 7.3e-34 115.3 0.1 1.3e-33 114.4 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGG11987.1 - 2.6e-29 101.5 0.1 4.6e-29 100.7 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGG11987.1 - 2.8e-17 61.9 6.6 5.8e-17 60.9 4.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGG11987.1 - 3.9e-15 55.2 0.0 1.2e-14 53.7 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Lactamase_B PF00753.22 EGG11988.1 - 7.4e-21 74.6 0.0 1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGG11988.1 - 0.00094 18.7 0.1 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGG11988.1 - 0.079 12.6 0.2 0.19 11.4 0.1 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain CoA_transf_3 PF02515.12 EGG11990.1 - 1.3e-56 190.9 0.0 1.6e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III DUF3613 PF12266.3 EGG11991.1 - 0.017 14.5 2.4 0.044 13.3 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3613) F-box-like PF12937.2 EGG11992.1 - 0.068 12.9 0.0 0.18 11.5 0.0 1.8 1 1 0 1 1 1 0 F-box-like ParA PF10609.4 EGG11996.1 - 1.1e-32 111.7 0.1 1.9e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGG11996.1 - 8.2e-18 64.5 0.0 1.3e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EGG11996.1 - 4e-07 29.3 0.2 3.6e-05 22.9 0.4 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EGG11996.1 - 1.2e-06 28.6 0.0 4.4e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EGG11996.1 - 0.00016 20.8 0.1 0.001 18.2 0.1 2.0 1 1 0 1 1 1 1 ATPase MipZ YhjQ PF06564.7 EGG11996.1 - 0.0089 15.4 0.3 0.014 14.7 0.2 1.4 1 1 0 1 1 1 1 YhjQ protein AAA_25 PF13481.1 EGG11996.1 - 0.018 14.4 0.0 0.046 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGG11996.1 - 0.021 14.0 0.1 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_26 PF13500.1 EGG11996.1 - 0.053 13.1 0.1 3 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain SelB-wing_3 PF09107.6 EGG11996.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix zf-C4_ClpX PF06689.8 EGG11996.1 - 0.13 11.8 1.2 0.32 10.5 0.9 1.7 1 0 0 1 1 1 0 ClpX C4-type zinc finger DLIC PF05783.6 EGG11997.1 - 0.21 10.2 4.9 0.13 10.9 2.5 1.3 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) VP4_haemagglut PF00426.13 EGG11997.1 - 0.21 9.4 0.6 0.28 9.1 0.4 1.0 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) SNF2_N PF00176.18 EGG11998.1 - 4.3e-69 232.5 0.0 6.4e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGG11998.1 - 5.4e-10 39.0 0.0 1.5e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG11998.1 - 5.8e-07 29.5 0.0 1.7e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EGG11998.1 - 0.00029 19.7 0.0 0.00068 18.5 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 GIDA PF01134.17 EGG12000.1 - 7.2e-09 34.9 0.3 1.4e-07 30.7 0.3 2.0 1 1 1 2 2 2 2 Glucose inhibited division protein A Adenylate_cycl PF01295.13 EGG12000.1 - 0.05 11.8 0.1 0.059 11.6 0.0 1.0 1 0 0 1 1 1 0 Adenylate cyclase, class-I LEAP-2 PF07359.6 EGG12001.1 - 0.073 12.7 0.4 21 4.8 0.2 3.1 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) DASH_Spc19 PF08287.6 EGG12002.1 - 2.3e-12 46.7 15.6 3e-12 46.4 10.8 1.2 1 0 0 1 1 1 1 Spc19 DPCD PF14913.1 EGG12002.1 - 0.0034 16.5 3.1 0.0065 15.5 0.4 1.9 1 1 1 2 2 2 1 DPCD protein family Kinesin-related PF06548.6 EGG12002.1 - 0.0045 15.6 11.5 0.0053 15.3 8.0 1.0 1 0 0 1 1 1 1 Kinesin-related BLOC1_2 PF10046.4 EGG12002.1 - 0.059 13.5 8.9 0.37 10.9 0.1 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WXG100 PF06013.7 EGG12002.1 - 0.19 11.7 1.0 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF948 PF06103.6 EGG12002.1 - 1.9 8.3 10.9 7.2 6.5 0.4 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.16 EGG12002.1 - 3.1 7.8 8.1 19 5.2 0.1 2.8 2 1 0 2 2 2 0 bZIP transcription factor AAA_23 PF13476.1 EGG12002.1 - 9.9 6.4 13.5 13 6.0 9.4 1.2 1 0 0 1 1 1 0 AAA domain CitT PF12431.3 EGG12003.1 - 0.07 13.2 0.2 0.22 11.6 0.1 1.9 1 0 0 1 1 1 0 Transcriptional regulator Metal_resist PF13801.1 EGG12004.1 - 0.086 12.8 0.3 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 Heavy-metal resistance PNP_UDP_1 PF01048.15 EGG12005.1 - 2.7e-38 131.2 0.0 3.6e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Perilipin PF03036.11 EGG12007.1 - 6.9e-08 31.7 4.7 8.1e-06 24.9 0.0 2.4 1 1 1 2 2 2 2 Perilipin family Apolipoprotein PF01442.13 EGG12007.1 - 3.9e-05 23.2 7.4 0.00015 21.3 3.8 2.5 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Spc7 PF08317.6 EGG12007.1 - 0.0024 16.6 7.9 0.0032 16.1 5.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Mis14 PF08641.7 EGG12007.1 - 0.035 14.1 4.4 0.1 12.6 3.1 1.9 1 1 0 1 1 1 0 Kinetochore protein Mis14 like Swi5 PF07061.6 EGG12007.1 - 0.039 13.7 1.8 0.065 13.0 0.3 2.1 2 0 0 2 2 2 0 Swi5 ApoLp-III PF07464.6 EGG12007.1 - 0.13 12.2 9.3 0.061 13.3 2.9 2.6 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.7 EGG12007.1 - 0.17 11.6 3.8 0.56 10.0 1.2 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EGG12007.1 - 0.39 10.5 3.3 2.9 7.7 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2408 PF10303.4 EGG12007.1 - 0.5 10.4 7.2 0.64 10.1 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF3391 PF11871.3 EGG12007.1 - 0.65 10.2 6.4 8 6.6 4.4 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) WXG100 PF06013.7 EGG12007.1 - 1.7 8.6 5.8 7.4 6.6 0.1 3.5 3 2 0 3 3 3 0 Proteins of 100 residues with WXG Sybindin PF04099.7 EGG12009.1 - 8.7e-39 132.4 0.0 9.5e-39 132.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EGG12009.1 - 2.4e-08 33.9 0.0 3.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Ctr PF04145.10 EGG12010.1 - 1.6e-27 96.3 5.0 2e-27 95.9 3.5 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Wzz PF02706.10 EGG12010.1 - 0.063 13.1 0.0 0.1 12.4 0.0 1.3 1 1 0 1 1 1 0 Chain length determinant protein Peptidase_S30 PF01577.11 EGG12011.1 - 7.6 5.8 15.7 0.46 9.8 4.9 2.3 2 0 0 2 2 2 0 Potyvirus P1 protease Rcd1 PF04078.8 EGG12012.1 - 1.3e-126 420.8 3.0 1.4e-126 420.6 2.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like adh_short PF00106.20 EGG12014.1 - 3.3e-22 79.1 0.1 4.4e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG12014.1 - 1.9e-11 43.9 0.8 5.9e-11 42.3 0.5 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGG12014.1 - 1.2e-08 35.0 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 EGG12014.1 - 2.7e-07 29.5 1.1 4.4e-07 28.8 0.8 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGG12014.1 - 0.00047 19.6 0.0 0.00066 19.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EGG12014.1 - 0.0016 17.5 0.0 0.0029 16.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EGG12014.1 - 0.026 13.4 0.1 0.046 12.6 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Alpha_kinase PF02816.13 EGG12017.1 - 1.1e-05 25.2 0.3 1.4e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Alpha-kinase family Apolipoprotein PF01442.13 EGG12019.1 - 8.5e-05 22.1 0.1 0.0002 20.9 0.0 1.6 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain HrcA PF01628.16 EGG12019.1 - 0.014 14.9 0.5 0.027 14.0 0.3 1.4 1 0 0 1 1 1 0 HrcA protein C terminal domain Octopine_DH PF02317.12 EGG12019.1 - 0.026 14.2 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Baculo_PEP_C PF04513.7 EGG12019.1 - 0.14 11.9 9.0 0.46 10.2 6.2 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus VPS9 PF02204.13 EGG12020.1 - 1.4e-30 105.4 0.0 3.2e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EGG12020.1 - 2e-05 23.9 0.2 0.00019 20.8 0.0 2.3 2 0 0 2 2 2 1 CUE domain DMA PF03474.9 EGG12020.1 - 0.0084 15.9 0.1 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 DMRTA motif HORMA PF02301.13 EGG12021.1 - 1.7e-43 148.5 0.0 1.7e-43 148.5 0.0 2.5 2 0 0 2 2 2 1 HORMA domain PHD PF00628.24 EGG12021.1 - 5.7e-06 25.9 9.4 1.1e-05 25.0 6.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EGG12021.1 - 0.0013 17.9 2.6 0.0027 16.9 1.8 1.5 1 0 0 1 1 1 1 PHD-finger MarR PF01047.17 EGG12021.1 - 0.1 12.2 0.0 0.1 12.2 0.0 3.3 3 0 0 3 3 3 0 MarR family GPI-anchored PF10342.4 EGG12022.1 - 2e-05 24.9 0.3 5.6e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pkinase PF00069.20 EGG12024.1 - 3.2e-74 249.3 0.0 3.7e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG12024.1 - 1.1e-32 113.1 0.0 4e-32 111.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG12024.1 - 0.009 14.9 0.0 0.023 13.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGG12024.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 HMG_box PF00505.14 EGG12025.1 - 0.041 14.1 0.2 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box Pkinase PF00069.20 EGG12026.1 - 4.9e-07 29.1 0.0 4.9e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG12026.1 - 0.0018 17.4 0.0 0.0018 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF872 PF05915.7 EGG12027.1 - 0.041 13.7 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) UL97 PF06734.7 EGG12027.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 UL97 MBOAT PF03062.14 EGG12029.1 - 9.9e-43 146.4 23.3 9.9e-43 146.4 16.1 2.5 2 1 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family DUF3733 PF12534.3 EGG12029.1 - 0.051 12.8 0.1 0.051 12.8 0.1 2.3 3 0 0 3 3 3 0 Leucine-rich repeat containing protein 8 Ribosomal_L28e PF01778.12 EGG12030.1 - 1.8e-25 89.6 0.1 1.8e-25 89.6 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EGG12030.1 - 2.5e-24 85.2 17.5 5.4e-24 84.2 12.1 1.5 1 0 0 1 1 1 1 Mak16 protein C-terminal region U1snRNP70_N PF12220.3 EGG12030.1 - 1.3 9.4 4.6 0.23 11.7 0.2 2.0 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF1547 PF07577.6 EGG12033.1 - 0.0034 17.0 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1547) HSP90 PF00183.13 EGG12035.1 - 1.5e-251 835.4 32.2 2.2e-251 834.8 22.3 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EGG12035.1 - 3.6e-12 46.0 0.3 3.6e-12 46.0 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGG12035.1 - 5.9e-12 45.2 0.0 1.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Colicin PF01024.14 EGG12036.1 - 0.00087 18.9 7.6 0.0011 18.6 4.0 1.7 1 1 1 2 2 2 1 Colicin pore forming domain Med15_fungi PF05397.7 EGG12036.1 - 0.094 12.6 4.4 0.17 11.8 0.1 2.8 1 1 2 3 3 3 0 Mediator complex subunit 15 NEP PF10167.4 EGG12036.1 - 0.11 12.1 7.0 0.29 10.8 0.2 2.2 1 1 1 2 2 2 0 Uncharacterised conserved protein TPR_MLP1_2 PF07926.7 EGG12036.1 - 2.9 7.6 16.8 0.26 11.0 5.2 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF946 PF06101.6 EGG12037.1 - 4.5e-09 34.8 0.5 2.2e-08 32.5 0.1 1.9 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) DUF2967 PF11179.3 EGG12040.1 - 0.00062 19.3 1.3 0.00093 18.7 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2967) RRM_1 PF00076.17 EGG12041.1 - 4e-28 96.8 3.6 5.6e-14 51.5 0.0 5.2 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG12041.1 - 1.4e-18 66.6 0.3 1.6e-06 28.0 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG12041.1 - 3.4e-15 55.6 1.0 7.1e-05 22.5 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 EGG12048.1 - 0.05 13.3 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EGG12048.1 - 0.074 12.7 0.2 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.2 EGG12048.1 - 0.9 9.2 4.9 46 3.7 0.6 3.7 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) FTHFS PF01268.14 EGG12049.1 - 0.0016 16.5 0.0 0.0018 16.3 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase NT-C2 PF10358.4 EGG12053.1 - 1.4e-17 63.5 0.1 2.4e-13 49.7 0.0 2.7 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Nup35_RRM PF05172.8 EGG12055.1 - 2.4e-15 56.1 0.0 4.7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EGG12055.1 - 2.1e-06 27.4 0.0 3.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3813 PF12758.2 EGG12057.1 - 0.065 13.3 3.9 0.42 10.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Cytochrom_C_2 PF01322.15 EGG12057.1 - 0.65 10.5 4.8 1 9.9 3.3 1.3 1 1 0 1 1 1 0 Cytochrome C' Rhomboid PF01694.17 EGG12058.1 - 3.5e-16 59.5 12.1 2.1e-15 56.9 8.4 2.2 1 1 0 1 1 1 1 Rhomboid family zf-C2H2 PF00096.21 EGG12059.1 - 0.0047 17.2 10.3 1.1 9.6 2.9 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type Elf1 PF05129.8 EGG12059.1 - 0.046 13.4 0.3 0.093 12.4 0.2 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-4CXXC_R1 PF10497.4 EGG12059.1 - 0.053 13.6 2.7 0.12 12.5 1.9 1.5 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-H2C2_2 PF13465.1 EGG12059.1 - 0.071 13.4 1.1 0.071 13.4 0.7 3.5 3 0 0 3 3 3 0 Zinc-finger double domain PyrI_C PF02748.10 EGG12059.1 - 0.11 11.9 3.2 0.23 10.9 2.2 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.1 EGG12059.1 - 0.3 11.5 10.0 1.2 9.5 0.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Sgf11 PF08209.6 EGG12059.1 - 0.42 9.9 6.3 0.13 11.6 0.9 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2_jaz PF12171.3 EGG12059.1 - 5.1 7.3 7.6 0.18 11.9 0.7 2.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF98 PF01947.11 EGG12060.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF98) HSP70 PF00012.15 EGG12061.1 - 2.3e-70 237.1 0.3 3.4e-70 236.6 0.2 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGG12061.1 - 2.2e-10 39.6 0.0 1.3e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.3 EGG12061.1 - 0.0015 17.4 0.2 0.14 11.0 0.0 2.1 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; DUF4611 PF15387.1 EGG12061.1 - 0.17 12.0 3.1 1.5 9.0 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NTF2 PF02136.15 EGG12063.1 - 4.8e-28 97.9 0.1 9.2e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EGG12063.1 - 6.3e-09 35.3 0.0 1.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG12063.1 - 0.00014 21.6 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG12063.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF905 PF06006.7 EGG12064.1 - 0.66 9.3 2.7 1.2 8.5 1.9 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Metallophos PF00149.23 EGG12065.1 - 7.6e-15 54.8 0.6 1.6e-14 53.8 0.4 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGG12065.1 - 1.6e-06 28.0 0.0 3.8e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain 4HBT PF03061.17 EGG12066.1 - 2.4e-23 82.0 2.5 1.2e-12 47.8 0.1 2.4 2 0 0 2 2 2 2 Thioesterase superfamily ATP-synt_ab PF00006.20 EGG12067.1 - 5.4e-70 235.2 0.0 7.6e-70 234.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGG12067.1 - 3.5e-21 75.7 0.0 1e-20 74.3 0.0 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGG12067.1 - 1e-18 67.3 2.1 2.4e-18 66.0 1.3 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EGG12067.1 - 8.6e-05 22.3 1.2 0.00021 21.0 0.8 1.7 1 0 0 1 1 1 1 HAS barrel domain AAA_25 PF13481.1 EGG12067.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Abhydrolase_5 PF12695.2 EGG12068.1 - 0.00012 21.8 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG12068.1 - 0.00047 20.1 0.1 0.0008 19.3 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EGG12068.1 - 0.0024 17.2 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGG12068.1 - 0.0026 17.3 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.13 EGG12068.1 - 0.006 15.9 0.0 0.025 13.9 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 2) Peptidase_S9 PF00326.16 EGG12068.1 - 0.064 12.4 0.1 7.7 5.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family LCAT PF02450.10 EGG12068.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase ATP-synt_D PF01813.12 EGG12069.1 - 0.0079 15.7 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 2 ATP synthase subunit D Guanylate_kin PF00625.16 EGG12070.1 - 3.4e-54 183.0 0.0 4.2e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EGG12070.1 - 1.8e-06 27.8 0.0 3.6e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGG12070.1 - 0.0001 22.4 0.0 0.0012 18.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGG12070.1 - 0.0006 19.0 0.1 0.00098 18.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGG12070.1 - 0.0014 18.6 0.1 0.013 15.4 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGG12070.1 - 0.0016 19.2 0.0 0.0023 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGG12070.1 - 0.002 18.4 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 EGG12070.1 - 0.0023 17.9 0.0 0.0065 16.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGG12070.1 - 0.0025 18.1 0.0 0.0083 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EGG12070.1 - 0.018 14.6 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGG12070.1 - 0.026 14.1 0.0 0.072 12.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 EGG12070.1 - 0.03 13.9 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EGG12070.1 - 0.034 13.6 1.7 0.065 12.7 0.4 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EGG12070.1 - 0.037 14.1 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EGG12070.1 - 0.039 13.6 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EGG12070.1 - 0.054 13.6 0.1 0.17 12.0 0.0 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EGG12070.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 EGG12070.1 - 0.092 12.7 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EGG12070.1 - 0.096 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGG12070.1 - 0.098 12.0 0.1 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain Voltage_CLC PF00654.15 EGG12071.1 - 2e-85 286.9 28.8 2e-85 286.9 20.0 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EGG12071.1 - 3.1e-05 23.6 0.0 0.033 13.9 0.0 3.1 3 0 0 3 3 3 2 CBS domain Glyco_tranf_2_3 PF13641.1 EGG12072.1 - 7.4e-27 94.6 0.0 1.3e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGG12072.1 - 1.3e-10 41.2 0.0 2.5e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGG12072.1 - 1.3e-08 34.3 0.0 2.9e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 PIG-P PF08510.7 EGG12072.1 - 0.0096 15.5 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 1 PIG-P Aminotran_1_2 PF00155.16 EGG12076.1 - 1e-19 70.7 0.0 3.3e-18 65.7 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II MFS_1 PF07690.11 EGG12077.1 - 6.9e-26 90.7 25.6 6.9e-26 90.7 17.8 2.4 1 1 0 2 2 2 1 Major Facilitator Superfamily TM_helix PF05552.7 EGG12077.1 - 0.042 13.5 1.7 3.2 7.5 0.0 2.9 2 0 0 2 2 2 0 Conserved TM helix ESSS PF10183.4 EGG12077.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Flavokinase PF01687.12 EGG12078.1 - 1.5e-29 102.4 0.1 2.4e-29 101.7 0.1 1.3 1 1 0 1 1 1 1 Riboflavin kinase DUF4250 PF14056.1 EGG12078.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Alpha_GJ PF03229.8 EGG12079.1 - 0.00039 20.7 6.1 0.00039 20.7 4.3 2.3 1 1 1 2 2 2 1 Alphavirus glycoprotein J DUF604 PF04646.7 EGG12079.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Ndc1_Nup PF09531.5 EGG12079.1 - 3.9 5.7 5.9 6.8 4.9 4.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PMT PF02366.13 EGG12080.1 - 6e-76 255.0 14.9 1.3e-75 253.9 10.4 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGG12080.1 - 1.6e-21 76.7 3.9 3.6e-20 72.3 1.0 2.2 1 1 1 2 2 2 2 MIR domain LRR_4 PF12799.2 EGG12081.1 - 0.92 9.2 8.0 19 5.0 0.1 4.6 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) SNF2_N PF00176.18 EGG12083.1 - 6.3e-71 238.6 8.8 8.4e-69 231.6 6.1 2.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGG12083.1 - 4.4e-18 64.9 0.0 1.3e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGG12083.1 - 6.1e-13 48.2 0.9 6.1e-13 48.2 0.6 2.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SOBP PF15279.1 EGG12083.1 - 8.4 6.6 22.6 6.8 6.9 7.1 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein DnaJ_CXXCXGXG PF00684.14 EGG12084.1 - 0.00012 22.0 7.1 0.00077 19.4 0.6 2.2 2 0 0 2 2 2 2 DnaJ central domain Pkinase PF00069.20 EGG12085.1 - 1e-69 234.6 0.0 1.3e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG12085.1 - 2.4e-30 105.4 0.0 3.2e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG12085.1 - 0.0045 16.7 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Spexin PF15171.1 EGG12088.1 - 0.79 9.7 4.6 0.99 9.4 0.4 2.5 1 1 1 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin DUF4519 PF15012.1 EGG12088.1 - 3.7 7.5 5.7 14 5.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) Ribonuc_P_40 PF08584.6 EGG12091.1 - 2.2e-23 82.6 0.0 4.5e-23 81.6 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit CAP59_mtransfer PF11735.3 EGG12097.1 - 2.9e-08 33.2 0.0 4.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ras PF00071.17 EGG12100.1 - 1.4e-09 37.5 0.5 1.5e-08 34.1 0.3 1.9 1 1 0 1 1 1 1 Ras family DUF1829 PF08862.5 EGG12100.1 - 0.12 12.6 0.4 0.23 11.7 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF1829 RHINO PF15319.1 EGG12105.1 - 0.025 14.3 0.4 0.039 13.7 0.3 1.2 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein DUF3578 PF12102.3 EGG12108.1 - 0.12 11.9 0.1 0.26 10.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3578) Lipase_GDSL PF00657.17 EGG12114.1 - 0.0036 17.1 0.0 0.033 14.0 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL PF00657.17 EGG12115.1 - 6.4e-11 42.5 0.1 8.2e-11 42.1 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL PF00657.17 EGG12116.1 - 2.8e-06 27.3 0.1 4.7e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase IL12 PF03039.9 EGG12116.1 - 0.043 12.9 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Interleukin-12 alpha subunit L-fibroin PF05849.6 EGG12116.1 - 0.055 12.7 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Fibroin light chain (L-fibroin) Hydrolase_like2 PF13246.1 EGG12118.1 - 3.7e-11 42.8 0.0 1.3e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EGG12118.1 - 0.026 13.5 0.7 0.054 12.5 0.5 1.6 1 1 0 1 1 1 0 E1-E2 ATPase Abhydrolase_6 PF12697.2 EGG12119.1 - 1.4e-28 100.3 0.0 2.6e-28 99.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG12119.1 - 3.6e-13 49.4 0.0 9.9e-13 48.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG12119.1 - 1.1e-11 44.7 0.0 1e-10 41.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGG12119.1 - 6.9e-06 25.8 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 EGG12119.1 - 0.00051 19.7 0.0 0.00083 19.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LIP PF03583.9 EGG12119.1 - 0.0039 16.4 0.1 0.0093 15.1 0.0 1.6 2 0 0 2 2 2 1 Secretory lipase DUF1057 PF06342.7 EGG12119.1 - 0.016 14.0 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DLH PF01738.13 EGG12119.1 - 0.13 11.4 0.0 0.37 10.0 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family WD40 PF00400.27 EGG12121.1 - 1.8e-69 227.3 33.0 2.9e-10 39.6 0.0 12.0 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 EGG12121.1 - 2e-17 63.0 1.1 3.5e-17 62.3 0.8 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EGG12121.1 - 6.7e-08 31.1 1.0 0.0081 14.3 0.1 4.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EGG12121.1 - 0.0015 18.2 0.5 0.039 13.6 0.0 2.9 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Methyltransf_31 PF13847.1 EGG12122.1 - 3.7e-12 46.0 0.0 5.3e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG12122.1 - 8.5e-11 42.4 0.0 1.3e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG12122.1 - 3.2e-06 26.6 0.0 4.5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EGG12122.1 - 5.4e-06 26.8 0.0 1.1e-05 25.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG12122.1 - 9.8e-06 25.8 0.0 1.6e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG12122.1 - 2.6e-05 24.6 0.0 3.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGG12122.1 - 0.00023 20.3 0.0 0.00031 19.9 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 EGG12122.1 - 0.00027 20.9 0.0 0.0004 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG12122.1 - 0.0005 19.8 0.0 0.00067 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGG12122.1 - 0.0014 18.3 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EGG12122.1 - 0.0045 17.0 0.4 0.0098 16.0 0.1 1.6 2 0 0 2 2 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.7 EGG12122.1 - 0.0058 16.0 0.1 0.0085 15.4 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 EGG12122.1 - 0.011 14.7 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.6 EGG12122.1 - 0.018 13.7 0.0 0.025 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PrmA PF06325.8 EGG12122.1 - 0.17 11.0 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HTH_44 PF14641.1 EGG12124.1 - 0.047 13.6 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 Metal_CEHH PF14455.1 EGG12125.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted metal binding domain Cation_efflux PF01545.16 EGG12128.1 - 1.3e-19 70.4 5.6 1.5e-19 70.1 3.9 1.1 1 0 0 1 1 1 1 Cation efflux family Cation_efflux PF01545.16 EGG12129.1 - 3.1e-15 56.0 0.9 4.7e-15 55.4 0.6 1.3 1 0 0 1 1 1 1 Cation efflux family WD40 PF00400.27 EGG12131.1 - 7.2e-37 123.9 3.7 6.3e-07 29.0 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGG12131.1 - 8.6e-05 22.3 0.1 0.00029 20.5 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.11 EGG12132.1 - 1.9e-20 72.8 36.4 1.1e-19 70.3 8.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 EGG12133.1 - 2.7e-12 46.4 0.3 6.6e-12 45.1 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 DUF313 PF03754.8 EGG12134.1 - 0.11 12.4 0.4 1.6 8.6 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF313) Glyco_hydro_43 PF04616.9 EGG12137.1 - 4.3e-08 32.5 1.2 0.00011 21.3 0.1 2.7 2 1 1 3 3 3 3 Glycosyl hydrolases family 43 DUF377 PF04041.8 EGG12137.1 - 0.029 13.1 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF377) DUF1179 PF06678.6 EGG12139.1 - 0.058 13.7 8.9 0.045 14.0 4.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1179) DUF377 PF04041.8 EGG12140.1 - 0.0064 15.2 0.0 0.011 14.5 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF377) Peptidase_M17 PF00883.16 EGG12142.1 - 5.4e-115 383.5 0.0 4.1e-114 380.6 0.0 1.9 1 1 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EGG12142.1 - 2.1e-07 30.7 0.0 3.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Adeno_shaft PF00608.12 EGG12142.1 - 0.088 12.4 0.1 0.29 10.8 0.1 1.9 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) RabGAP-TBC PF00566.13 EGG12143.1 - 7.7e-21 74.5 0.9 1.8e-20 73.3 0.6 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Kelch_3 PF13415.1 EGG12144.1 - 4.6e-32 109.4 9.5 2.8e-10 40.0 0.1 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EGG12144.1 - 5e-22 77.4 13.2 3.2e-07 30.0 0.1 6.7 6 2 0 6 6 6 4 Galactose oxidase, central domain DUF4110 PF13422.1 EGG12144.1 - 3.3e-17 62.1 1.2 3.3e-17 62.1 0.8 4.6 4 2 1 5 5 5 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 EGG12144.1 - 2.6e-16 59.0 11.6 8.2e-05 22.6 0.0 5.6 4 1 2 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EGG12144.1 - 3.1e-15 55.4 4.0 0.0054 16.2 0.0 5.3 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 EGG12144.1 - 2.1e-14 53.0 6.9 0.0028 17.5 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EGG12144.1 - 4.9e-11 41.9 7.9 0.0063 16.2 0.1 5.0 4 1 0 4 4 4 3 Kelch motif ACT PF01842.20 EGG12144.1 - 0.6 9.6 3.3 0.41 10.1 0.3 2.1 2 0 0 2 2 2 0 ACT domain Peptidase_S29 PF02907.10 EGG12146.1 - 0.0025 17.3 0.0 0.0027 17.2 0.0 1.0 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Rad52_Rad22 PF04098.10 EGG12148.1 - 4.2e-57 192.2 0.0 4.9e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Prenyltrans PF00432.16 EGG12150.1 - 5.4e-34 115.4 0.9 6.6e-08 31.9 0.0 6.4 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGG12150.1 - 2.8e-20 72.8 0.0 1.7e-08 34.8 0.0 4.0 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGG12150.1 - 3.8e-07 30.1 0.0 0.0029 17.6 0.0 2.6 2 1 0 2 2 2 2 Prenyltransferase-like Alpha_kinase PF02816.13 EGG12152.1 - 2.4e-24 86.0 0.5 2.4e-24 86.0 0.3 2.7 3 0 0 3 3 3 2 Alpha-kinase family Lipase_GDSL_3 PF14606.1 EGG12152.1 - 0.025 14.3 0.2 2.5 7.7 0.0 2.9 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_11 PF00457.12 EGG12152.1 - 0.047 13.0 1.8 0.056 12.7 0.1 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 11 DUF3527 PF12043.3 EGG12152.1 - 0.054 13.0 10.6 0.087 12.3 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) SNF2_N PF00176.18 EGG12154.1 - 2.6e-63 213.6 0.0 3.7e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EGG12154.1 - 2.2e-26 92.8 6.3 2.8e-26 92.4 3.5 1.8 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 EGG12154.1 - 1.1e-12 47.6 0.0 2.4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG12154.1 - 0.00092 19.0 0.0 0.0031 17.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EGG12154.1 - 0.019 13.8 0.0 0.074 11.8 0.0 2.0 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 EIF_2_alpha PF07541.7 EGG12155.1 - 1.4e-39 134.3 0.0 3e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EGG12155.1 - 5.2e-13 48.8 0.7 1.2e-12 47.7 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain AP_endonuc_2 PF01261.19 EGG12155.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel EzrA PF06160.7 EGG12156.1 - 0.00079 17.7 9.9 0.002 16.4 6.8 1.6 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA PGC7_Stella PF15549.1 EGG12156.1 - 0.16 11.9 2.2 0.27 11.1 1.5 1.4 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain DUF1409 PF07197.7 EGG12156.1 - 0.19 11.8 0.3 0.19 11.8 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1409) Fib_alpha PF08702.5 EGG12156.1 - 0.93 9.6 8.6 2.6 8.1 5.5 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.8 EGG12156.1 - 1.8 9.3 4.5 2.2 9.0 0.8 2.6 2 1 1 3 3 3 0 Occludin homology domain TBPIP PF07106.8 EGG12156.1 - 8.4 5.9 14.8 13 5.2 6.2 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Kinesin PF00225.18 EGG12157.1 - 2.6e-82 276.2 0.5 1.5e-75 253.9 0.1 2.2 2 0 0 2 2 2 2 Kinesin motor domain CAML PF14963.1 EGG12157.1 - 1.2 8.4 5.2 1.5 8.1 0.4 2.3 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand DUF1310 PF07006.6 EGG12159.1 - 0.066 12.7 0.3 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) Brr6_like_C_C PF10104.4 EGG12160.1 - 4.1e-38 129.9 7.0 4.7e-38 129.7 4.8 1.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain WD40 PF00400.27 EGG12161.1 - 1.8e-22 78.3 5.9 3.9e-05 23.3 0.0 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat SR-25 PF10500.4 EGG12161.1 - 0.06 12.8 2.3 0.11 11.9 1.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein INCENP_ARK-bind PF03941.10 EGG12162.1 - 6.4e-11 41.9 0.7 6.4e-11 41.9 0.5 2.0 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region SIR2 PF02146.12 EGG12163.1 - 4.1e-56 189.5 0.0 4.9e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Sir2 family CutC PF03932.9 EGG12163.1 - 0.16 11.1 0.1 0.46 9.7 0.0 1.7 2 0 0 2 2 2 0 CutC family RRM_1 PF00076.17 EGG12168.1 - 2e-43 145.8 0.1 3.2e-18 65.1 0.0 4.2 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG12168.1 - 2.2e-34 117.2 0.0 6e-14 51.7 0.0 4.1 3 1 1 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG12168.1 - 3.3e-25 87.7 0.0 8.4e-09 35.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGG12168.1 - 0.00041 20.0 0.0 0.0098 15.6 0.0 2.5 2 1 0 2 2 2 1 Limkain b1 DUF1777 PF08648.7 EGG12168.1 - 0.0032 17.2 28.9 0.0053 16.5 20.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) CDC45 PF02724.9 EGG12168.1 - 8.1 4.3 8.5 11 3.9 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PPTA PF01239.17 EGG12171.1 - 2.5e-32 108.8 8.3 5.5e-08 31.8 0.0 5.2 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DNA_pol3_delt_C PF14840.1 EGG12171.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term DUF4219 PF13961.1 EGG12171.1 - 8.6 5.9 6.9 27 4.3 0.8 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) PAS_9 PF13426.1 EGG12172.1 - 3.1e-26 91.7 0.0 9.3e-15 54.8 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 EGG12172.1 - 7.6e-17 61.1 0.0 1e-07 31.7 0.0 4.1 3 1 0 3 3 3 3 PAS fold PAS_3 PF08447.6 EGG12172.1 - 1.8e-13 50.4 0.0 2.3e-08 33.9 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 EGG12172.1 - 1.2e-10 41.3 0.1 0.00011 22.0 0.0 2.7 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.5 EGG12172.1 - 1.9e-07 31.0 0.0 0.00024 21.1 0.0 3.6 3 0 0 3 3 3 1 PAS fold SIS PF01380.17 EGG12173.1 - 2.9e-57 191.8 0.6 8.3e-31 106.3 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EGG12173.1 - 9.7e-26 90.3 0.0 1.1e-17 63.8 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGG12173.1 - 8.3e-19 67.8 0.0 1.7e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EGG12173.1 - 3e-14 52.8 0.0 6.9e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EGG12173.1 - 3.5e-08 32.4 0.1 6.3e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EGG12173.1 - 0.0092 15.6 0.0 0.41 10.3 0.0 2.4 2 0 0 2 2 2 1 SIS domain BCDHK_Adom3 PF10436.4 EGG12174.1 - 2.1e-66 222.4 0.0 2.9e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGG12174.1 - 9.1e-21 73.6 0.0 6.9e-19 67.6 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGG12174.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Abhydrolase_6 PF12697.2 EGG12175.1 - 4.3e-28 98.7 0.0 8.9e-28 97.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG12175.1 - 6.3e-15 55.3 0.0 7.9e-15 55.0 0.0 1.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGG12175.1 - 1.4e-12 47.5 0.0 3.4e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGG12175.1 - 1.7e-06 27.7 0.1 4.3e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Putative lysophospholipase DUF1057 PF06342.7 EGG12175.1 - 0.00039 19.3 0.0 0.00068 18.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.8 EGG12175.1 - 0.035 13.7 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.13 EGG12175.1 - 0.062 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family MCM PF00493.18 EGG12177.1 - 8.4e-88 294.3 6.5 4.5e-72 242.6 2.3 3.2 1 1 1 2 2 2 2 MCM2/3/5 family Mg_chelatase PF01078.16 EGG12177.1 - 3.6e-07 29.5 0.0 7.9e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF2151 PF10221.4 EGG12177.1 - 0.0029 15.8 0.2 0.0044 15.2 0.2 1.2 1 0 0 1 1 1 1 Cell cycle and development regulator ABC_trans_N PF14510.1 EGG12177.1 - 0.032 14.3 0.8 0.093 12.8 0.6 1.8 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal Sigma54_activat PF00158.21 EGG12177.1 - 0.032 13.6 0.1 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Polyoma_coat2 PF00761.15 EGG12177.1 - 0.11 12.0 0.6 0.27 10.6 0.4 1.6 1 0 0 1 1 1 0 Polyomavirus coat protein SapB_1 PF05184.10 EGG12177.1 - 0.16 11.8 4.0 0.29 11.0 0.4 2.4 2 0 0 2 2 2 0 Saposin-like type B, region 1 NAS PF03059.11 EGG12178.1 - 0.11 11.5 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein Response_reg PF00072.19 EGG12179.1 - 1.8e-28 98.7 0.0 2.1e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.19 EGG12180.1 - 2.4e-20 72.5 0.1 3.3e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain IF4E PF01652.13 EGG12181.1 - 1.5e-20 73.3 0.4 2e-20 73.0 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Chitin_synth_2 PF03142.10 EGG12182.1 - 6.3e-17 61.1 0.1 7e-17 60.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glycos_transf_2 PF00535.21 EGG12182.1 - 0.031 13.9 0.0 0.077 12.6 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 PDCD2_C PF04194.8 EGG12184.1 - 0.13 11.8 1.5 0.7 9.4 1.0 1.8 1 1 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain DUF3708 PF12501.3 EGG12186.1 - 0.017 14.9 0.2 0.022 14.5 0.1 1.1 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter NAM-associated PF14303.1 EGG12186.1 - 0.049 13.9 0.8 0.06 13.6 0.5 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Adeno_E3_15_3 PF03307.9 EGG12186.1 - 0.059 13.1 2.7 0.075 12.7 1.9 1.2 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Dfp1_Him1_M PF08630.5 EGG12186.1 - 0.06 13.1 0.1 0.077 12.7 0.1 1.2 1 0 0 1 1 1 0 Dfp1/Him1, central region PspA_IM30 PF04012.7 EGG12186.1 - 0.083 12.2 4.4 0.1 11.9 3.0 1.1 1 0 0 1 1 1 0 PspA/IM30 family DUF972 PF06156.8 EGG12186.1 - 0.96 9.8 7.3 0.6 10.4 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 EGG12186.1 - 1.4 8.9 8.2 12 5.9 5.0 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.6 EGG12186.1 - 2 8.3 4.9 17 5.4 0.2 2.7 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Nucleoporin_N PF08801.6 EGG12188.1 - 3.7e-14 52.3 0.7 6.8e-14 51.4 0.0 1.7 2 0 0 2 2 2 1 Nup133 N terminal like Nucleoporin_C PF03177.9 EGG12188.1 - 1e-06 27.5 0.2 1.4e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal FH2 PF02181.18 EGG12189.1 - 0.081 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain Cep57_CLD_2 PF14197.1 EGG12193.1 - 0.058 13.3 0.3 0.097 12.6 0.2 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 JmjC PF02373.17 EGG12195.1 - 0.00052 20.2 0.0 0.0022 18.1 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase SCO1-SenC PF02630.9 EGG12195.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC NAD_synthase PF02540.12 EGG12196.1 - 0.013 14.3 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 NAD synthase CDC45 PF02724.9 EGG12198.1 - 0.096 10.7 24.1 0.11 10.4 16.7 1.3 1 0 0 1 1 1 0 CDC45-like protein PTRF_SDPR PF15237.1 EGG12198.1 - 0.19 11.0 21.5 0.27 10.5 14.9 1.2 1 0 0 1 1 1 0 PTRF/SDPR family DUF4404 PF14357.1 EGG12198.1 - 0.71 10.3 11.9 3.1 8.2 1.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF572 PF04502.8 EGG12198.1 - 1.2 8.3 27.6 1.8 7.7 19.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) FliT PF05400.8 EGG12198.1 - 1.2 9.5 6.0 0.32 11.4 0.2 2.2 2 0 0 2 2 2 0 Flagellar protein FliT Parvo_coat PF00740.13 EGG12198.1 - 1.8 7.3 10.4 2.1 7.1 7.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Daxx PF03344.10 EGG12198.1 - 2.5 6.4 27.9 3.9 5.8 19.4 1.3 1 0 0 1 1 1 0 Daxx Family CAF-1_p150 PF11600.3 EGG12198.1 - 2.5 7.3 34.7 4 6.7 24.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Adeno_VII PF03228.9 EGG12198.1 - 3.4 8.2 8.7 2.8 8.5 4.7 1.8 1 1 1 2 2 2 0 Adenoviral core protein VII RR_TM4-6 PF06459.7 EGG12198.1 - 4.1 7.2 23.0 6.2 6.6 16.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Corona_nucleoca PF00937.13 EGG12198.1 - 8.6 5.1 22.4 12 4.7 15.5 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein VLPT PF07122.6 EGG12199.1 - 0.098 12.3 0.8 0.17 11.5 0.5 1.4 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) Macoilin PF09726.4 EGG12201.1 - 0.96 7.6 3.9 1.1 7.4 2.7 1.2 1 0 0 1 1 1 0 Transmembrane protein ORC6 PF05460.8 EGG12201.1 - 1.6 7.7 7.4 2.2 7.2 5.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Histone PF00125.19 EGG12203.1 - 4.6e-29 100.3 0.5 5.6e-29 100.0 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGG12203.1 - 0.0038 17.3 0.4 0.0057 16.8 0.3 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EGG12203.1 - 0.054 12.7 0.1 0.059 12.6 0.1 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EGG12203.1 - 0.19 11.7 1.0 0.35 10.9 0.7 1.5 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TMF_DNA_bd PF12329.3 EGG12204.1 - 0.0014 18.4 5.6 0.0014 18.4 3.9 3.2 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EGG12204.1 - 0.053 13.1 10.9 0.079 12.5 3.4 2.4 2 0 0 2 2 2 0 IncA protein ATG16 PF08614.6 EGG12204.1 - 0.18 11.6 11.0 0.024 14.4 3.1 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4363 PF14276.1 EGG12204.1 - 0.76 9.4 3.4 0.43 10.2 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Syntaxin-6_N PF09177.6 EGG12204.1 - 1.4 9.3 8.5 4.1 7.8 1.0 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Mnd1 PF03962.10 EGG12204.1 - 1.7 8.2 9.4 0.55 9.8 3.3 2.1 2 0 0 2 2 2 0 Mnd1 family CCDC-167 PF15188.1 EGG12204.1 - 3.9 7.4 13.4 1.4 8.9 6.5 2.3 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 APG6 PF04111.7 EGG12204.1 - 4.7 6.1 11.0 0.25 10.3 3.3 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EGG12204.1 - 9.1 3.9 8.4 14 3.4 5.8 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Vezatin PF12632.2 EGG12205.1 - 0.0016 17.5 0.1 1.3 8.0 0.0 2.9 3 0 0 3 3 3 2 Mysoin-binding motif of peroxisomes FixP_N PF14715.1 EGG12205.1 - 0.38 10.1 0.7 0.65 9.4 0.5 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP NMD3 PF04981.8 EGG12206.1 - 3.5e-74 248.8 2.3 5.3e-74 248.3 1.6 1.3 1 0 0 1 1 1 1 NMD3 family NinF PF05810.7 EGG12206.1 - 0.013 15.2 0.4 0.5 10.1 0.1 2.8 2 0 0 2 2 2 0 NinF protein DZR PF12773.2 EGG12206.1 - 0.06 13.1 6.7 0.24 11.2 2.6 2.9 2 1 0 2 2 2 0 Double zinc ribbon GcpE PF04551.9 EGG12206.1 - 0.07 11.9 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 GcpE protein Dsl1_C PF11989.3 EGG12207.1 - 7.5e-08 31.8 0.1 8.4e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal YyzF PF14116.1 EGG12207.1 - 0.15 12.0 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 YyzF-like protein Alpha_adaptinC2 PF02883.15 EGG12208.1 - 0.089 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Adaptin C-terminal domain DEAD PF00270.24 EGG12210.1 - 3.7e-38 130.6 0.0 6.2e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGG12210.1 - 6.8e-21 73.5 0.1 1.4e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGG12210.1 - 3.3e-17 62.1 0.0 8e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG12210.1 - 0.0016 18.3 0.4 0.0036 17.1 0.0 1.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DTHCT PF08070.6 EGG12213.1 - 0.034 14.8 0.8 0.034 14.8 0.6 1.8 2 0 0 2 2 2 0 DTHCT (NUC029) region Spt20 PF12090.3 EGG12214.1 - 2.9e-34 117.9 19.1 3e-33 114.7 0.0 3.2 3 0 0 3 3 3 2 Spt20 family zf-RING_2 PF13639.1 EGG12215.1 - 1.7e-12 46.9 12.3 3e-12 46.1 8.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGG12215.1 - 1.6e-07 31.3 8.7 3.4e-07 30.2 6.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGG12215.1 - 4.3e-06 26.3 15.6 7.2e-06 25.6 10.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGG12215.1 - 5.6e-06 26.2 13.4 1e-05 25.4 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG12215.1 - 8.6e-05 22.1 13.9 0.00014 21.4 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG12215.1 - 0.00038 20.0 12.7 0.00072 19.1 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGG12215.1 - 0.005 16.6 6.1 0.0097 15.7 4.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGG12215.1 - 0.0095 15.6 4.4 0.0095 15.6 3.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger Apc15p PF05841.6 EGG12215.1 - 0.078 13.7 13.6 0.044 14.5 3.9 3.2 3 0 0 3 3 2 0 Apc15p protein zf-Nse PF11789.3 EGG12215.1 - 0.11 12.0 8.2 0.22 11.0 5.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EGG12215.1 - 0.36 10.6 8.3 0.74 9.6 5.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FANCL_C PF11793.3 EGG12215.1 - 1.3 9.0 10.9 3.8 7.5 7.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain CBF PF03914.12 EGG12216.1 - 1e-43 148.6 1.6 4.3e-43 146.6 0.2 1.9 1 1 1 2 2 2 2 CBF/Mak21 family MoCF_biosynth PF00994.19 EGG12217.1 - 1.5e-28 99.0 0.0 3e-28 98.0 0.0 1.5 1 1 0 1 1 1 1 Probable molybdopterin binding domain WD40 PF00400.27 EGG12219.1 - 3.4e-13 48.8 1.6 1.1 9.2 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Mem_trans PF03547.13 EGG12221.1 - 0.48 8.6 3.2 1.4 7.0 0.3 2.1 2 0 0 2 2 2 0 Membrane transport protein Rep_fac-A_3 PF08661.6 EGG12222.1 - 3.6e-25 87.9 0.0 4.3e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Mt_ATP-synt_B PF05405.9 EGG12223.1 - 1.2e-45 154.8 6.2 1.4e-45 154.6 4.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2461 PF09365.5 EGG12223.1 - 0.0021 17.5 0.3 0.0044 16.4 0.1 1.6 1 1 1 2 2 2 1 Conserved hypothetical protein (DUF2461) DUF465 PF04325.8 EGG12223.1 - 0.018 14.7 0.2 0.055 13.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF465) DUF1539 PF07560.6 EGG12223.1 - 0.094 12.5 0.6 0.18 11.6 0.4 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) DASH_Duo1 PF08651.5 EGG12223.1 - 0.28 10.7 3.0 9.6 5.8 0.0 3.0 1 1 1 3 3 3 0 DASH complex subunit Duo1 RRP7 PF12923.2 EGG12223.1 - 1.6 8.7 4.7 2.6 8.0 2.4 1.9 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) SH3_1 PF00018.23 EGG12225.1 - 2.4e-15 55.6 2.0 7.9e-07 28.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain RA PF00788.18 EGG12225.1 - 2.9e-14 53.2 0.3 6.7e-14 52.1 0.2 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_9 PF14604.1 EGG12225.1 - 1e-10 41.0 1.5 1.7e-06 27.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EGG12225.1 - 2.4e-10 39.7 0.3 2.2e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SAM_2 PF07647.12 EGG12225.1 - 4e-07 29.7 0.0 9.7e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGG12225.1 - 0.00086 19.4 0.1 0.0017 18.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2360 PF10152.4 EGG12225.1 - 5 7.3 16.4 9.9e+02 -0.1 11.4 2.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 EGG12225.1 - 5.3 6.3 23.7 9.2 5.5 16.4 1.3 1 0 0 1 1 1 0 Vta1 like DUF445 PF04286.7 EGG12226.1 - 0.23 10.9 3.4 0.23 10.9 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) PI3Ka PF00613.15 EGG12227.1 - 6.9e-49 165.5 0.0 1.1e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EGG12227.1 - 6.8e-40 137.0 0.0 3.5e-38 131.3 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EGG12227.1 - 2.3e-19 69.5 0.0 3.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 cEGF PF12662.2 EGG12228.1 - 0.012 15.2 0.4 0.058 13.0 0.3 2.2 1 0 0 1 1 1 0 Complement Clr-like EGF-like WD40 PF00400.27 EGG12229.1 - 9e-10 38.0 11.3 0.00047 19.9 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat PLU-1 PF08429.6 EGG12232.1 - 0.0052 15.7 1.3 0.0064 15.4 0.9 1.0 1 0 0 1 1 1 1 PLU-1-like protein DMAP_binding PF06464.6 EGG12232.1 - 0.045 14.3 0.3 0.089 13.3 0.2 1.5 1 1 0 1 1 1 0 DMAP1-binding Domain Ribosomal_S5 PF00333.15 EGG12233.1 - 2.7e-16 59.0 0.1 4.5e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EGG12233.1 - 9.8e-15 53.6 0.0 2.1e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Glyco_hydro_76 PF03663.9 EGG12234.1 - 3.2e-54 184.7 7.6 4.3e-54 184.3 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EGG12234.1 - 0.025 13.6 2.0 1.3 7.9 0.1 2.7 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 RPAP1_N PF08621.5 EGG12235.1 - 2.6e-07 30.1 2.6 7.4e-07 28.6 1.8 1.9 1 0 0 1 1 1 1 RPAP1-like, N-terminal RPAP1_C PF08620.5 EGG12235.1 - 0.0074 16.1 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal BCIP PF13862.1 EGG12237.1 - 4.2e-42 143.8 0.3 1.3e-40 139.0 0.2 2.1 1 1 0 1 1 1 1 p21-C-terminal region-binding protein UPF0506 PF11703.3 EGG12238.1 - 0.12 12.3 2.4 1.8 8.5 0.3 2.3 2 0 0 2 2 2 0 UPF0506 Tim44 PF04280.10 EGG12240.1 - 3.1e-07 30.5 0.0 7.9e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Tim44-like domain Cwf_Cwc_15 PF04889.7 EGG12240.1 - 0.03 14.0 0.2 0.046 13.4 0.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRF PF01765.14 EGG12240.1 - 0.051 13.0 1.2 0.088 12.2 0.8 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF1104 PF06518.6 EGG12240.1 - 0.14 12.2 2.0 0.24 11.5 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) FAM176 PF14851.1 EGG12243.1 - 0.27 10.9 3.3 0.62 9.7 2.3 1.5 1 0 0 1 1 1 0 FAM176 family tRNA_bind PF01588.15 EGG12244.1 - 6.2e-28 96.4 0.1 1e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EGG12244.1 - 8.5e-05 22.9 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.20 EGG12245.1 - 1.3e-62 211.2 0.0 1.7e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG12245.1 - 3.7e-34 117.9 0.0 5.1e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG12245.1 - 0.0011 17.9 0.1 0.0026 16.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like GCS PF03074.11 EGG12245.1 - 0.0069 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase Gly_transf_sug PF04488.10 EGG12249.1 - 5.7e-09 36.2 0.0 1.3e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EGG12249.1 - 2e-05 23.8 0.0 3.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EGG12249.1 - 0.00017 20.1 0.0 0.00028 19.5 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain DUF1752 PF08550.5 EGG12251.1 - 7.4e-12 44.6 3.2 1.4e-11 43.6 2.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Rft-1 PF04506.8 EGG12253.1 - 7.5e-71 239.1 15.2 1.3e-70 238.3 10.5 1.3 1 0 0 1 1 1 1 Rft protein Ank_4 PF13637.1 EGG12254.1 - 2.2e-12 47.0 0.6 0.00026 21.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EGG12254.1 - 7e-12 44.5 0.7 5.6e-05 22.7 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EGG12254.1 - 2.4e-11 43.8 0.2 1.7e-08 34.6 0.1 2.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGG12254.1 - 6.6e-11 41.3 0.7 0.0014 18.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGG12254.1 - 2.2e-10 40.4 0.4 0.00088 19.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DEAD PF00270.24 EGG12255.1 - 3.4e-42 143.7 0.5 5.9e-42 143.0 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG12255.1 - 2e-23 82.0 0.2 4.3e-23 80.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EGG12255.1 - 0.0061 15.6 0.1 0.015 14.4 0.1 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Pex14_N PF04695.8 EGG12255.1 - 2.3 8.2 9.1 4.5 7.3 6.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Synaphin PF05835.7 EGG12256.1 - 0.0041 17.2 0.2 0.0066 16.6 0.1 1.3 1 0 0 1 1 1 1 Synaphin protein DUF4358 PF14270.1 EGG12256.1 - 0.17 11.7 1.7 0.32 10.8 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) CytochromB561_N PF09786.4 EGG12256.1 - 0.28 9.6 4.4 0.32 9.3 3.1 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Gon7 PF08738.5 EGG12256.1 - 0.4 10.6 4.0 0.2 11.6 0.6 1.9 1 1 1 2 2 2 0 Gon7 family Cytochrom_C_2 PF01322.15 EGG12257.1 - 0.048 14.1 1.7 0.062 13.8 1.2 1.3 1 0 0 1 1 1 0 Cytochrome C' DUF4316 PF14195.1 EGG12257.1 - 0.15 12.1 1.0 0.25 11.4 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) DUF3813 PF12758.2 EGG12257.1 - 0.28 11.3 3.9 0.31 11.2 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) DUF3682 PF12446.3 EGG12257.1 - 1.9 8.7 7.4 2.5 8.4 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) ADH_zinc_N PF00107.21 EGG12258.1 - 2.7e-11 43.1 0.0 6.6e-11 41.8 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGG12258.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ALIX_LYPXL_bnd PF13949.1 EGG12260.1 - 0.0048 15.9 4.5 0.0067 15.4 3.1 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Laminin_II PF06009.7 EGG12260.1 - 0.07 12.8 0.2 0.28 10.9 0.1 1.8 2 0 0 2 2 2 0 Laminin Domain II Herpes_UL25 PF01499.11 EGG12260.1 - 0.14 10.4 4.2 0.18 10.1 2.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Alpha_kinase PF02816.13 EGG12265.1 - 0.00022 20.9 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family Ribosomal_L21p PF00829.16 EGG12268.1 - 2.4e-06 27.5 0.5 4.2e-06 26.7 0.3 1.4 1 1 0 1 1 1 1 Ribosomal prokaryotic L21 protein A_deamin PF02137.13 EGG12269.1 - 5.7e-55 187.0 0.0 9.4e-54 183.0 0.0 2.1 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Lipase_GDSL PF00657.17 EGG12270.1 - 7.6e-06 25.9 0.1 1.2e-05 25.2 0.0 1.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Plasmod_dom_1 PF09715.5 EGG12270.1 - 0.0057 16.5 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Plasmodium protein of unknown function (Plasmod_dom_1) FlxA PF14282.1 EGG12270.1 - 0.034 14.0 0.9 1.9 8.4 0.2 2.3 2 0 0 2 2 2 0 FlxA-like protein PXPV PF12778.2 EGG12271.1 - 0.061 13.0 4.1 22 4.8 0.1 3.3 3 0 0 3 3 3 0 PXPV repeat (3 copies) Viral_Beta_CD PF04530.7 EGG12273.1 - 0.45 10.6 3.3 0.87 9.7 2.3 1.5 1 0 0 1 1 1 0 Viral Beta C/D like family Glyco_hydro_16 PF00722.16 EGG12275.1 - 1.8e-10 40.4 0.0 3.7e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Myb_Cef PF11831.3 EGG12281.1 - 0.0053 16.0 1.0 0.0053 16.0 0.7 1.6 2 0 0 2 2 2 1 pre-mRNA splicing factor component Methyltransf_11 PF08241.7 EGG12282.1 - 6e-09 36.2 0.0 1.1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG12282.1 - 4.9e-06 26.3 0.0 6.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG12282.1 - 2.9e-05 24.5 0.0 5.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG12282.1 - 0.0009 18.8 0.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EGG12282.1 - 0.0025 17.8 0.0 0.01 15.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG12282.1 - 0.0072 16.7 0.0 0.095 13.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGG12282.1 - 0.0087 15.4 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EGG12282.1 - 0.016 14.2 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 EGG12282.1 - 0.021 14.8 0.0 0.047 13.6 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase p450 PF00067.17 EGG12283.1 - 1.6e-58 198.3 0.0 1.9e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EGG12284.1 - 1.1e-55 183.5 7.1 4.4e-11 42.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EGG12284.1 - 1.8e-10 39.9 5.8 3.1e-10 39.1 4.0 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 EGG12284.1 - 0.014 14.4 0.0 2.2 7.2 0.0 2.8 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal CENP-B_dimeris PF09026.5 EGG12284.1 - 0.03 14.5 1.6 0.062 13.5 1.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nup160 PF11715.3 EGG12284.1 - 0.088 10.9 0.4 6 4.8 0.1 3.0 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoplasmin PF03066.10 EGG12284.1 - 4.2 6.8 7.2 6.9 6.1 5.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin zf-H2C2_5 PF13909.1 EGG12285.1 - 0.0053 16.9 2.6 0.015 15.5 1.8 1.8 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EGG12285.1 - 0.0083 16.4 3.7 0.02 15.2 2.6 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGG12285.1 - 0.07 13.4 3.0 0.18 12.1 2.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGG12285.1 - 0.15 12.4 2.2 8.1 6.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain MBOAT_2 PF13813.1 EGG12286.1 - 3.5e-12 46.2 0.7 5e-12 45.7 0.5 1.3 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT PF03062.14 EGG12286.1 - 0.034 13.2 0.3 0.09 11.8 0.0 1.8 2 0 0 2 2 2 0 MBOAT, membrane-bound O-acyltransferase family p450 PF00067.17 EGG12289.1 - 3.1e-54 184.2 0.0 3.9e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dynamin_M PF01031.15 EGG12290.1 - 3.5e-109 364.1 0.2 6.3e-109 363.3 0.2 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EGG12290.1 - 1.2e-52 178.1 0.1 2.2e-52 177.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EGG12290.1 - 1e-28 99.0 0.1 2.5e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGG12290.1 - 0.0045 16.9 0.0 0.019 14.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGG12290.1 - 0.023 15.2 0.0 0.054 13.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF2419 PF10343.4 EGG12290.1 - 0.17 11.1 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) zf-C2H2 PF00096.21 EGG12291.1 - 0.0056 16.9 1.9 0.02 15.2 1.3 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type Glyco_hydro_10 PF00331.15 EGG12292.1 - 0.19 10.7 0.1 0.32 9.9 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 MS_channel PF00924.13 EGG12294.1 - 7.4e-17 61.3 1.0 1.8e-16 60.1 0.7 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.1 EGG12294.1 - 7.1e-09 34.8 0.5 0.00015 21.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EGG12294.1 - 1.8e-08 33.0 2.7 6.2e-05 22.0 0.6 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGG12294.1 - 2.5e-07 30.7 0.4 0.0084 16.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGG12294.1 - 5.5e-05 22.3 3.9 0.00077 18.7 0.5 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EGG12294.1 - 0.045 13.3 2.7 1.7 8.3 0.3 2.4 1 1 1 2 2 2 0 EF-hand domain pair Striatin PF08232.7 EGG12294.1 - 0.66 10.2 0.0 0.66 10.2 0.0 3.7 4 1 0 4 4 4 0 Striatin family Sec62 PF03839.11 EGG12294.1 - 0.88 8.9 4.5 0.69 9.2 0.0 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 Ank_4 PF13637.1 EGG12296.1 - 2e-10 40.8 0.8 1.1e-05 25.8 0.1 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGG12296.1 - 7e-10 39.1 0.1 4.9e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGG12296.1 - 2.5e-08 33.3 0.4 0.00042 19.9 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EGG12296.1 - 3.3e-07 29.8 0.7 0.013 15.6 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EGG12296.1 - 4.5e-07 29.9 0.2 0.0002 21.5 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PDZ_assoc PF10600.4 EGG12297.1 - 0.036 14.3 0.2 3.4 8.0 0.2 2.3 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors P5-ATPase PF12409.3 EGG12299.1 - 0.12 12.1 0.5 3.8 7.4 0.1 2.4 2 0 0 2 2 2 0 P5-type ATPase cation transporter Transket_pyr PF02779.19 EGG12303.1 - 3.4e-67 225.3 0.0 1.2e-66 223.5 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EGG12303.1 - 7.5e-55 185.7 0.0 1.1e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Glyco_hydro_47 PF01532.15 EGG12305.1 - 6e-138 460.2 0.0 6.8e-138 460.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA14 PF07691.7 EGG12305.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 PA14 domain Thioredoxin PF00085.15 EGG12307.1 - 1.6e-29 101.6 2.7 2.7e-24 84.8 0.1 2.5 1 1 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EGG12307.1 - 3.3e-09 36.9 2.7 1.5e-07 31.5 0.1 2.5 1 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGG12307.1 - 2.1e-08 34.1 0.2 1.1e-05 25.5 0.1 2.8 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EGG12307.1 - 5.5e-06 26.3 0.0 1.9e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 EGG12307.1 - 0.00021 20.9 0.2 0.0052 16.4 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EGG12307.1 - 0.0046 16.5 1.5 0.062 12.8 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_4 PF13462.1 EGG12307.1 - 0.11 12.5 1.8 2 8.3 1.2 2.2 1 1 0 1 1 1 0 Thioredoxin Redoxin PF08534.5 EGG12307.1 - 0.21 11.1 3.5 0.43 10.1 0.3 2.2 1 1 1 2 2 2 0 Redoxin STT3 PF02516.9 EGG12308.1 - 1.5e-128 429.8 39.3 4.8e-128 428.1 27.3 1.7 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Smoothelin PF12510.3 EGG12310.1 - 0.099 12.5 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein EmrE PF13536.1 EGG12311.1 - 0.018 15.2 1.0 0.018 15.2 0.7 3.0 4 0 0 4 4 4 0 Multidrug resistance efflux transporter DUF1149 PF06619.6 EGG12311.1 - 0.037 13.9 3.7 0.13 12.1 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1149) RPAP2_Rtr1 PF04181.8 EGG12312.1 - 9.8e-14 51.2 0.3 9.8e-14 51.2 0.2 1.8 2 0 0 2 2 2 1 Rtr1/RPAP2 family zf-FCS PF06467.9 EGG12312.1 - 0.0015 18.1 0.3 0.0033 17.0 0.2 1.6 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif Med3 PF11593.3 EGG12312.1 - 0.02 14.1 0.1 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LRR_8 PF13855.1 EGG12313.1 - 4.6e-05 23.0 7.8 0.17 11.6 0.2 5.0 3 3 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EGG12313.1 - 0.00015 21.3 9.3 0.65 9.6 0.1 5.3 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG12315.1 - 5.4e-05 22.8 10.5 0.76 9.5 0.0 4.5 2 2 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EGG12315.1 - 0.0018 17.8 22.6 3.3 7.4 2.2 5.8 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) Methyltransf_31 PF13847.1 EGG12315.1 - 0.088 12.3 1.0 5 6.7 0.0 2.5 2 1 1 3 3 3 0 Methyltransferase domain LRR_4 PF12799.2 EGG12317.1 - 0.00095 18.7 6.8 0.52 9.9 0.4 5.0 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG12317.1 - 0.14 11.8 11.5 0.66 9.7 0.5 4.6 5 1 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 EGG12320.1 - 6.7e-05 22.4 11.7 0.62 9.7 0.8 5.2 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG12320.1 - 0.0054 16.4 10.7 11 5.8 0.3 5.4 2 1 3 6 6 5 4 Leucine rich repeat PET PF06297.9 EGG12320.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 PET Domain Gal_mutarotas_2 PF13802.1 EGG12322.1 - 1.1e-08 34.7 0.1 1.4e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Galactose mutarotase-like Spermine_synth PF01564.12 EGG12323.1 - 3.2e-77 258.7 0.0 4.1e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_12 PF08242.7 EGG12323.1 - 0.035 14.5 0.0 0.091 13.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Saccharop_dh PF03435.13 EGG12324.1 - 6.2e-33 114.3 0.0 2.5e-31 109.0 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase Bac_export_2 PF01312.14 EGG12325.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family zf-CCHC_6 PF15288.1 EGG12326.1 - 0.26 10.9 1.7 0.5 10.0 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle GlutR_N PF05201.10 EGG12327.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain AFT PF08731.6 EGG12330.1 - 0.046 13.9 0.1 0.046 13.9 0.1 2.7 3 0 0 3 3 3 0 Transcription factor AFT DBD_Tnp_Mut PF03108.10 EGG12330.1 - 0.14 11.7 0.0 8.1 6.1 0.0 2.3 2 0 0 2 2 2 0 MuDR family transposase LRR_4 PF12799.2 EGG12333.1 - 0.00015 21.3 3.9 0.15 11.7 0.1 4.3 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG12333.1 - 3.3 7.5 8.2 7.9 6.3 0.3 4.5 3 2 2 6 6 6 0 Leucine rich repeat F-box-like PF12937.2 EGG12335.1 - 0.00067 19.3 1.8 0.015 15.0 1.2 2.6 1 1 0 1 1 1 1 F-box-like DUF4414 PF14377.1 EGG12335.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) F-box-like_2 PF13013.1 EGG12335.1 - 0.015 15.0 0.1 0.045 13.4 0.1 1.9 1 0 0 1 1 1 0 F-box-like domain LRR_8 PF13855.1 EGG12335.1 - 5.9 6.7 11.5 8.8 6.1 0.3 4.7 5 0 0 5 5 5 0 Leucine rich repeat MitMem_reg PF13012.1 EGG12336.1 - 1.9e-14 53.7 6.0 1e-13 51.3 4.1 2.2 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EGG12336.1 - 6.2e-11 42.0 0.2 6.9e-10 38.6 0.0 2.5 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-E2_B PF14461.1 EGG12336.1 - 0.041 13.6 0.2 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B F-box-like PF12937.2 EGG12337.1 - 1.8e-05 24.3 0.1 4.5e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGG12337.1 - 0.0023 17.5 1.5 0.037 13.6 1.1 2.6 1 1 0 1 1 1 1 F-box domain TPT PF03151.11 EGG12339.1 - 1.3e-28 99.5 17.0 2.2e-26 92.3 4.6 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EGG12339.1 - 3.9e-14 52.2 17.3 2.7e-13 49.4 12.0 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGG12339.1 - 2.4e-09 37.2 29.9 5.3e-05 23.2 4.4 2.9 2 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EGG12339.1 - 4.8e-06 26.7 19.1 0.00066 19.8 4.7 2.9 2 1 0 2 2 2 2 Multidrug resistance efflux transporter LMF1 PF06762.9 EGG12339.1 - 0.032 13.0 3.9 0.051 12.3 2.7 1.2 1 0 0 1 1 1 0 Lipase maturation factor DUF3683 PF12447.3 EGG12340.1 - 0.0038 17.0 0.2 0.007 16.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3683) Ferritin_2 PF13668.1 EGG12341.1 - 2e-45 154.1 0.1 4.1e-45 153.0 0.0 1.5 2 0 0 2 2 2 1 Ferritin-like domain Rubrerythrin PF02915.12 EGG12341.1 - 0.015 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Rubrerythrin Ferritin_2 PF13668.1 EGG12342.1 - 8.5e-46 155.3 0.0 1.2e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 EGG12342.1 - 0.0097 16.2 0.1 0.02 15.2 0.1 1.5 1 0 0 1 1 1 1 Rubrerythrin Ferritin_2 PF13668.1 EGG12344.1 - 6.7e-47 158.8 0.5 1e-46 158.3 0.3 1.3 1 0 0 1 1 1 1 Ferritin-like domain Smoothelin PF12510.3 EGG12345.1 - 0.0033 17.2 2.1 0.0042 16.9 0.6 1.8 1 1 1 2 2 2 1 Smoothelin cytoskeleton protein Pex14_N PF04695.8 EGG12345.1 - 0.04 13.9 0.1 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPT PF03151.11 EGG12346.1 - 3.9e-37 127.2 6.2 3.9e-37 127.2 4.3 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EGG12346.1 - 3.4e-12 45.9 26.2 9.3e-07 28.0 6.6 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EGG12346.1 - 7.1e-12 45.4 34.3 1.6e-06 28.1 8.6 2.8 3 1 0 3 3 3 2 EamA-like transporter family PCI PF01399.22 EGG12347.1 - 9.9e-18 64.3 0.2 9.9e-18 64.3 0.1 2.6 3 0 0 3 3 3 1 PCI domain TPR_7 PF13176.1 EGG12347.1 - 1.7e-05 24.2 0.2 3 7.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGG12347.1 - 0.0033 17.3 1.3 14 5.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Xpo1 PF08389.7 EGG12347.1 - 0.012 15.5 1.0 0.43 10.4 0.0 3.1 3 1 0 3 3 3 0 Exportin 1-like protein TPR_1 PF00515.23 EGG12347.1 - 0.025 14.2 1.2 5.9 6.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGG12347.1 - 3.1 7.7 7.9 55 3.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Histone PF00125.19 EGG12352.1 - 3.5e-26 91.1 0.0 4.4e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGG12352.1 - 1.2e-05 25.2 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Alpha_kinase PF02816.13 EGG12353.1 - 1.8e-21 76.6 4.4 6.1e-21 74.9 0.4 2.6 2 0 0 2 2 2 1 Alpha-kinase family DUF3584 PF12128.3 EGG12353.1 - 9.8e-05 19.9 0.2 9.8e-05 19.9 0.1 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Histone PF00125.19 EGG12354.1 - 1e-22 79.9 0.1 1.4e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGG12354.1 - 1.6e-05 24.8 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EGG12354.1 - 0.0032 17.6 0.0 0.0048 17.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Plus-3 PF03126.13 EGG12355.1 - 1.2e-19 70.2 0.3 1.2e-19 70.2 0.2 1.9 2 0 0 2 2 2 1 Plus-3 domain Ribosomal_60s PF00428.14 EGG12356.1 - 1.6e-26 92.4 9.7 1.8e-26 92.3 6.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein WD40 PF00400.27 EGG12357.1 - 2.2e-11 43.1 3.9 0.00064 19.5 0.0 6.6 6 0 0 6 6 6 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGG12357.1 - 0.0021 17.5 0.2 0.14 11.6 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EGG12357.1 - 0.011 13.6 0.0 1.9 6.2 0.0 3.1 3 0 0 3 3 3 0 IKI3 family eIF2A PF08662.6 EGG12357.1 - 0.017 14.8 0.3 1e+02 2.5 0.0 5.4 6 0 0 6 6 6 0 Eukaryotic translation initiation factor eIF2A CytochromB561_N PF09786.4 EGG12358.1 - 1 7.6 7.7 1.5 7.2 5.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal PHD PF00628.24 EGG12359.1 - 9.2e-10 38.0 4.8 1.6e-09 37.3 3.3 1.4 1 0 0 1 1 1 1 PHD-finger BAH PF01426.13 EGG12359.1 - 1.4e-05 24.8 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 BAH domain Prok-RING_1 PF14446.1 EGG12359.1 - 0.0063 16.2 2.0 0.0063 16.2 1.4 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 EGG12359.1 - 0.14 12.0 4.7 0.32 10.8 3.2 1.7 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.17 EGG12359.1 - 1.2 8.8 6.6 0.19 11.4 1.5 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SurE PF01975.12 EGG12361.1 - 0.00042 19.6 0.0 0.00063 19.1 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Sterol_MT_C PF08498.5 EGG12362.1 - 7.5e-27 93.0 0.9 1.1e-26 92.5 0.6 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EGG12362.1 - 1.8e-18 66.7 0.0 3.5e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG12362.1 - 1e-17 64.1 0.0 2.4e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG12362.1 - 8e-14 51.6 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGG12362.1 - 9.1e-13 47.9 0.2 1.3e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EGG12362.1 - 2.8e-12 47.2 0.0 1.3e-11 45.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG12362.1 - 5.6e-12 45.9 0.2 1.6e-11 44.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG12362.1 - 6.5e-12 45.6 0.0 1.3e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGG12362.1 - 4.7e-09 35.7 0.0 7.8e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGG12362.1 - 3.1e-07 30.4 0.0 6.5e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EGG12362.1 - 1.9e-06 27.5 0.2 3.2e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Spermine_synth PF01564.12 EGG12362.1 - 0.00015 20.8 0.0 0.00027 19.9 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase PCMT PF01135.14 EGG12362.1 - 0.00017 21.2 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EGG12362.1 - 0.00036 19.9 0.0 0.00089 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EGG12362.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.13 EGG12362.1 - 0.0025 17.0 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.1 EGG12362.1 - 0.02 14.5 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 EGG12362.1 - 0.027 13.5 0.0 0.062 12.3 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase UPF0020 PF01170.13 EGG12362.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Glyco_hydro_18 PF00704.23 EGG12363.1 - 4.9e-98 328.7 3.2 6.3e-98 328.3 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SNARE_assoc PF09335.6 EGG12364.1 - 4.4e-17 62.4 5.2 7.8e-17 61.6 3.6 1.4 1 0 0 1 1 1 1 SNARE associated Golgi protein Lig_chan PF00060.21 EGG12364.1 - 0.68 9.6 3.7 0.34 10.6 0.5 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel UCH PF00443.24 EGG12365.1 - 4.3e-59 199.8 0.0 6.2e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGG12365.1 - 7.7e-22 78.0 0.0 1.1e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 EGG12365.1 - 5.2e-07 29.6 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain zf-MIZ PF02891.15 EGG12365.1 - 0.0065 15.9 0.4 0.014 14.9 0.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger MIT PF04212.13 EGG12365.1 - 0.032 14.1 0.2 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Clr2 PF10383.4 EGG12366.1 - 2.9e-07 30.5 0.0 2e-06 27.8 0.0 2.5 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 SAM_2 PF07647.12 EGG12367.1 - 0.096 12.5 0.1 0.4 10.5 0.1 2.0 1 1 1 2 2 2 0 SAM domain (Sterile alpha motif) K167R PF08065.7 EGG12369.1 - 2.5 8.2 7.7 3.9 7.6 1.3 2.8 2 1 0 2 2 2 0 K167R (NUC007) repeat RRM_6 PF14259.1 EGG12372.1 - 9.7e-16 57.5 0.0 3.9e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGG12372.1 - 8.3e-13 47.7 0.0 2.7e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG12372.1 - 0.027 14.3 0.0 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YebO PF13974.1 EGG12374.1 - 0.14 11.9 0.0 0.55 10.0 0.0 1.8 2 0 0 2 2 2 0 YebO-like protein Casein_kappa PF00997.13 EGG12375.1 - 0.14 11.9 5.1 0.26 11.0 3.5 1.3 1 0 0 1 1 1 0 Kappa casein DUF1640 PF07798.6 EGG12377.1 - 1.1e-58 198.2 6.5 1.2e-58 198.0 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Kinesin-related PF06548.6 EGG12377.1 - 0.0096 14.5 5.4 0.01 14.4 3.7 1.1 1 0 0 1 1 1 1 Kinesin-related HALZ PF02183.13 EGG12377.1 - 0.019 14.6 5.4 0.084 12.5 3.7 2.2 1 1 0 1 1 1 0 Homeobox associated leucine zipper CHD5 PF04420.9 EGG12377.1 - 0.053 13.1 1.6 0.095 12.3 1.1 1.4 1 0 0 1 1 1 0 CHD5-like protein COG5 PF10392.4 EGG12377.1 - 2.5 8.0 8.4 20 5.1 6.0 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF972 PF06156.8 EGG12377.1 - 4.2 7.7 6.3 7.1 7.0 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 EGG12377.1 - 8.8 6.3 7.6 23 4.9 1.2 3.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF544 PF04424.8 EGG12378.1 - 8.3e-18 64.3 0.0 1.3e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) F-box-like PF12937.2 EGG12380.1 - 0.00012 21.7 1.5 0.00012 21.7 1.0 2.4 2 0 0 2 2 2 1 F-box-like TPR_14 PF13428.1 EGG12380.1 - 0.11 13.1 0.0 0.37 11.5 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat NAD_binding_8 PF13450.1 EGG12381.1 - 1.4e-14 53.8 0.0 2.7e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGG12381.1 - 2.2e-05 23.7 0.1 2.4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EGG12381.1 - 7.7e-05 21.7 0.3 0.00011 21.2 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGG12381.1 - 0.00051 20.1 0.1 0.00064 19.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGG12381.1 - 0.0094 15.7 0.2 0.028 14.1 0.1 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EGG12381.1 - 0.04 14.3 0.1 0.065 13.6 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGG12381.1 - 0.091 11.2 0.1 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 EGG12381.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rifin_STEVOR PF02009.11 EGG12383.1 - 0.0017 18.0 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family BatA PF07584.6 EGG12383.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Plasmodium_Vir PF05795.6 EGG12383.1 - 1.5 7.9 4.7 0.3 10.2 0.7 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Vps5 PF09325.5 EGG12384.1 - 2.3e-52 177.6 10.2 3.5e-52 177.0 7.1 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EGG12384.1 - 2.2e-22 78.9 0.0 9.5e-22 76.9 0.0 2.1 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 EGG12384.1 - 0.00059 19.1 0.3 0.031 13.5 0.1 2.2 1 1 1 2 2 2 1 WASP-binding domain of Sorting nexin protein TIP120 PF08623.5 EGG12384.1 - 0.077 12.5 2.9 0.13 11.8 0.2 2.3 2 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) Asp PF00026.18 EGG12385.1 - 1.2e-59 202.1 0.9 1.4e-59 201.8 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGG12385.1 - 0.0002 21.3 0.3 0.00063 19.7 0.2 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGG12385.1 - 0.0011 19.4 2.8 0.75 10.3 0.2 3.2 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EGG12385.1 - 0.043 13.3 0.2 0.2 11.1 0.0 2.0 1 1 0 2 2 2 0 Xylanase inhibitor C-terminal SH3_1 PF00018.23 EGG12389.1 - 1.8e-34 116.8 7.3 1.1e-16 59.8 0.1 4.8 5 0 0 5 5 5 3 SH3 domain SH3_9 PF14604.1 EGG12389.1 - 5.6e-32 109.0 9.9 3.4e-14 52.1 0.1 5.0 6 0 0 6 6 6 3 Variant SH3 domain SHD1 PF03983.7 EGG12389.1 - 7.5e-26 89.5 0.0 1.4e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 EGG12389.1 - 4.8e-18 64.4 0.0 1.1e-08 34.4 0.0 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 EGG12389.1 - 0.00018 21.5 0.5 1.2 9.3 0.1 3.2 3 0 0 3 3 3 2 Bacterial SH3 domain DUF1720 PF08226.6 EGG12389.1 - 0.0093 16.0 33.5 0.0093 16.0 23.2 5.9 3 1 1 4 4 4 2 Domain of unknown function (DUF1720) LRR_8 PF13855.1 EGG12392.1 - 0.00039 20.1 1.4 0.043 13.5 0.0 2.9 3 0 0 3 3 3 2 Leucine rich repeat F-box-like PF12937.2 EGG12392.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like TSA PF03249.8 EGG12394.1 - 0.13 10.7 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Type specific antigen F-box-like PF12937.2 EGG12395.1 - 0.0063 16.2 0.2 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EGG12396.1 - 0.0032 17.1 0.0 0.0087 15.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF1510 PF07423.6 EGG12398.1 - 0.00081 18.8 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Flexi_CP_N PF08358.5 EGG12398.1 - 0.0082 15.8 0.0 2.3 8.0 0.0 2.4 2 0 0 2 2 2 2 Carlavirus coat BTB PF00651.26 EGG12399.1 - 0.12 12.3 0.1 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain TLD PF07534.11 EGG12400.1 - 9e-32 109.9 2.2 1.2e-31 109.5 1.5 1.2 1 0 0 1 1 1 1 TLD PNRC PF15365.1 EGG12401.1 - 3.3e-05 23.7 4.3 3.3e-05 23.7 3.0 2.6 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator MFS_1 PF07690.11 EGG12405.1 - 9.9e-24 83.6 20.1 3.9e-23 81.7 13.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TSP_1 PF00090.14 EGG12406.1 - 0.89 9.7 7.2 1.2 9.3 4.0 2.2 1 1 0 1 1 1 0 Thrombospondin type 1 domain Ribophorin_II PF05817.9 EGG12407.1 - 1.7e-20 72.8 0.0 2.1e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Rpn3_C PF08375.6 EGG12412.1 - 2.9e-24 85.2 0.1 8.2e-24 83.7 0.0 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EGG12412.1 - 4.7e-21 75.0 0.0 1.2e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 EGG12412.1 - 0.00054 19.7 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 EGG12412.1 - 0.00065 19.4 0.0 0.0024 17.6 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-MIZ PF02891.15 EGG12413.1 - 1.5 8.4 15.4 0.99 8.9 0.2 3.9 2 1 1 3 3 3 0 MIZ/SP-RING zinc finger CDC45 PF02724.9 EGG12414.1 - 0.21 9.5 4.0 0.25 9.3 2.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 EGG12415.1 - 2.5e-46 157.8 8.0 1e-45 155.8 4.8 1.9 2 0 0 2 2 2 1 Translocation protein Sec62 SHR3_chaperone PF08229.6 EGG12415.1 - 0.97 8.3 3.5 0.9 8.4 1.7 1.5 1 1 0 1 1 1 0 ER membrane protein SH3 Glyco_transf_90 PF05686.7 EGG12416.1 - 2.3e-15 56.1 1.0 5.9e-15 54.8 0.7 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_transf_90 PF05686.7 EGG12417.1 - 5.9e-16 58.1 2.7 2.6e-15 56.0 1.7 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 90 CbiG_N PF11760.3 EGG12417.1 - 0.073 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal Pox_polyA_pol_N PF12630.2 EGG12417.1 - 0.22 11.6 1.3 9.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain Cnd1 PF12717.2 EGG12418.1 - 1.4e-56 191.1 14.3 2.3e-54 183.9 1.7 4.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EGG12418.1 - 1.8e-39 135.1 0.9 1.8e-39 135.1 0.6 4.1 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.17 EGG12418.1 - 1.7e-07 30.7 0.2 2.6 8.3 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 EGG12418.1 - 3.5e-07 30.4 0.0 0.59 10.4 0.0 5.0 5 0 0 5 5 5 2 HEAT repeats PglZ PF08665.7 EGG12418.1 - 0.0053 16.4 1.5 0.61 9.7 0.1 3.4 2 1 0 2 2 2 1 PglZ domain HEAT_EZ PF13513.1 EGG12418.1 - 0.036 14.5 0.3 23 5.6 0.0 4.8 4 1 1 5 5 5 0 HEAT-like repeat Aldedh PF00171.17 EGG12422.1 - 7.3e-180 598.2 0.1 8.2e-180 598.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGG12422.1 - 0.042 12.5 0.0 0.087 11.5 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) IPI_T4 PF11634.3 EGG12422.1 - 0.069 13.0 0.2 0.42 10.5 0.0 2.4 3 0 0 3 3 3 0 Nuclease inhibitor from bacteriophage T4 zf-UBR PF02207.15 EGG12423.1 - 1.3e-13 50.4 13.4 1.3e-13 50.4 9.3 3.5 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 EGG12423.1 - 0.00019 21.0 6.6 0.00019 21.0 4.6 3.5 2 1 0 3 3 3 1 PHD-finger Swi5 PF07061.6 EGG12423.1 - 0.058 13.1 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Swi5 PHD_2 PF13831.1 EGG12423.1 - 8.4 5.8 13.2 1.2 8.5 1.2 3.6 3 0 0 3 3 3 0 PHD-finger PAS_9 PF13426.1 EGG12424.1 - 1.6e-05 25.2 0.0 0.018 15.3 0.0 3.2 2 1 0 2 2 2 2 PAS domain AAA_25 PF13481.1 EGG12425.1 - 3.1e-12 46.2 0.0 4.2e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGG12425.1 - 0.00025 20.2 0.0 0.0012 17.9 0.0 1.9 1 1 0 1 1 1 1 KaiC AAA_19 PF13245.1 EGG12425.1 - 0.00078 19.1 0.3 0.0022 17.7 0.1 1.8 1 1 1 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EGG12425.1 - 0.00087 19.4 0.0 0.0018 18.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGG12425.1 - 0.0026 17.2 0.0 0.006 16.0 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 EGG12425.1 - 0.0074 17.0 0.0 0.014 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EGG12425.1 - 0.025 14.8 0.1 0.052 13.7 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EGG12425.1 - 0.083 12.4 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-Apc11 PF12861.2 EGG12427.1 - 4.9 7.0 8.2 6.8 6.5 5.7 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Aminotran_5 PF00266.14 EGG12429.1 - 2.2e-11 43.1 0.0 9.9e-11 40.9 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V zf-CCCH PF00642.19 EGG12432.1 - 5.8e-05 22.6 1.3 5.8e-05 22.6 0.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3519 PF12033.3 EGG12433.1 - 0.054 13.6 0.2 0.054 13.6 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3519) NAD_Gly3P_dh_C PF07479.9 EGG12435.1 - 7e-49 165.3 0.1 1e-48 164.8 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EGG12435.1 - 4.9e-45 153.0 0.1 7.5e-45 152.4 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EGG12435.1 - 2.2e-05 24.8 0.1 0.26 11.7 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EGG12435.1 - 0.013 15.7 0.0 0.095 13.0 0.0 2.2 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PDGF_N PF04692.8 EGG12437.1 - 0.051 14.0 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region DUF429 PF04250.8 EGG12437.1 - 0.1 11.8 0.2 0.24 10.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF429) Baculo_PEP_C PF04513.7 EGG12438.1 - 0.011 15.5 1.7 0.019 14.7 1.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Borrelia_REV PF03978.8 EGG12438.1 - 0.012 15.3 4.4 0.048 13.3 3.1 1.9 1 1 0 1 1 1 0 Borrelia burgdorferi REV protein IFT57 PF10498.4 EGG12438.1 - 0.015 14.0 2.9 0.022 13.4 2.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Orthopox_A5L PF06193.6 EGG12438.1 - 0.021 14.7 1.9 0.035 14.0 1.3 1.4 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like TBPIP PF07106.8 EGG12438.1 - 0.032 13.7 2.6 0.058 12.9 1.8 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 EGG12438.1 - 0.036 14.3 2.2 0.1 12.8 1.3 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 EGG12438.1 - 0.043 13.6 2.6 0.094 12.5 1.8 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EGG12438.1 - 0.06 12.9 1.9 0.1 12.2 1.3 1.3 1 0 0 1 1 1 0 IncA protein DUF2317 PF10079.4 EGG12438.1 - 0.073 11.6 0.6 0.11 11.1 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) TPR_MLP1_2 PF07926.7 EGG12438.1 - 0.26 11.0 3.6 0.23 11.2 1.1 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 EGG12438.1 - 0.39 10.6 7.4 0.091 12.7 2.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) SseC PF04888.7 EGG12438.1 - 0.59 9.4 4.1 0.35 10.1 1.6 1.4 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family EF-hand_10 PF14788.1 EGG12441.1 - 0.046 13.3 0.1 0.096 12.3 0.1 1.5 1 0 0 1 1 1 0 EF hand LdpA_C PF12617.3 EGG12441.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal Frankia_peptide PF14407.1 EGG12443.1 - 0.0014 18.3 0.5 0.0026 17.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF3134 PF11332.3 EGG12443.1 - 1.8 8.7 5.7 1.5 9.0 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3134) Rop-like PF05082.8 EGG12445.1 - 0.0074 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Rop-like H-kinase_dim PF02895.9 EGG12445.1 - 0.01 16.1 1.2 0.3 11.4 0.8 2.2 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain GreA_GreB_N PF03449.10 EGG12445.1 - 0.016 15.2 0.5 0.51 10.4 0.0 2.1 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal Syntaxin-6_N PF09177.6 EGG12445.1 - 0.021 15.2 0.3 0.034 14.5 0.2 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Snapin_Pallidin PF14712.1 EGG12445.1 - 0.034 14.4 1.3 0.25 11.6 0.4 2.0 1 1 1 2 2 2 0 Snapin/Pallidin Phage_Orf51 PF06194.6 EGG12445.1 - 0.083 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Phage Conserved Open Reading Frame 51 Pet191_N PF10203.4 EGG12445.1 - 0.099 12.7 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 IncA PF04156.9 EGG12445.1 - 0.2 11.2 2.1 0.42 10.1 0.5 1.8 2 0 0 2 2 2 0 IncA protein RNA_pol_Rpc82 PF05645.8 EGG12447.1 - 0.15 11.5 6.6 1.2 8.5 4.1 2.3 2 1 0 2 2 2 0 RNA polymerase III subunit RPC82 AT_hook PF02178.14 EGG12447.1 - 9.4 6.2 9.3 0.2 11.4 1.4 2.1 2 0 0 2 2 2 0 AT hook motif Nop14 PF04147.7 EGG12448.1 - 1.3 6.8 19.9 2.2 6.0 13.8 1.2 1 0 0 1 1 1 0 Nop14-like family MIP PF00230.15 EGG12452.1 - 0.00011 21.7 0.5 0.00017 21.1 0.3 1.3 1 1 0 1 1 1 1 Major intrinsic protein U3_assoc_6 PF08640.6 EGG12453.1 - 0.15 11.8 2.7 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 TMF_DNA_bd PF12329.3 EGG12454.1 - 0.00098 18.8 1.7 0.025 14.3 0.0 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding Filament PF00038.16 EGG12454.1 - 0.011 15.2 3.3 0.011 15.2 2.3 1.7 1 1 0 1 1 1 0 Intermediate filament protein DUF4380 PF14315.1 EGG12454.1 - 0.018 14.2 0.1 0.02 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) Stn1_C PF12659.2 EGG12454.1 - 0.038 13.8 0.2 0.068 12.9 0.2 1.4 1 1 0 1 1 1 0 Telomere capping C-terminal wHTH DUF496 PF04363.7 EGG12454.1 - 0.051 13.4 1.3 0.16 11.8 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF496) Lebercilin PF15619.1 EGG12454.1 - 0.054 12.9 2.4 0.14 11.5 1.6 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Tropomyosin PF00261.15 EGG12454.1 - 0.067 12.2 8.0 0.66 9.0 0.4 2.1 1 1 1 2 2 2 0 Tropomyosin Med9 PF07544.8 EGG12454.1 - 0.11 12.2 1.0 0.27 10.9 0.5 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 zf-HYPF PF07503.7 EGG12454.1 - 0.11 11.9 0.4 0.21 11.0 0.3 1.5 1 0 0 1 1 1 0 HypF finger rpo30_N PF12410.3 EGG12454.1 - 0.15 11.7 1.1 7.3 6.2 0.1 2.3 2 1 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit Spc7 PF08317.6 EGG12454.1 - 0.28 9.7 5.1 0.4 9.2 3.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.3 EGG12454.1 - 0.48 10.3 4.5 1.2 9.0 1.0 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DS PF01916.12 EGG12455.1 - 2.2e-26 92.7 0.1 6.3e-17 61.6 0.0 2.0 2 0 0 2 2 2 2 Deoxyhypusine synthase TauD PF02668.11 EGG12460.1 - 9e-39 133.6 0.0 1.4e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EGG12460.1 - 5.9e-09 36.2 0.0 1.5e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF971) DUF2442 PF10387.4 EGG12460.1 - 0.043 13.8 0.0 0.76 9.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) 2-oxoacid_dh PF00198.18 EGG12461.1 - 3.2e-79 265.4 0.1 4.7e-79 264.9 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGG12461.1 - 4.7e-21 74.1 1.2 9.1e-21 73.2 0.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EGG12461.1 - 0.00031 20.3 1.7 0.079 12.6 0.0 2.8 2 1 1 3 3 3 2 Biotin-lipoyl like GCV_H PF01597.14 EGG12461.1 - 0.00068 19.3 0.3 0.0015 18.2 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.1 EGG12461.1 - 0.0012 19.1 0.2 0.096 13.0 0.0 2.6 1 1 1 2 2 2 1 HlyD family secretion protein PEGSRP PF07623.6 EGG12461.1 - 0.94 8.8 3.9 2.5 7.4 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) ELYS PF13934.1 EGG12462.1 - 6.7e-39 133.9 0.5 1.1e-38 133.2 0.3 1.3 1 0 0 1 1 1 1 Nuclear pore complex assembly MutS_V PF00488.16 EGG12463.1 - 6.7e-79 264.6 0.0 9.9e-79 264.0 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGG12463.1 - 3.6e-39 134.6 0.7 8e-39 133.5 0.2 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EGG12463.1 - 3.4e-30 104.3 0.1 8.6e-30 103.0 0.0 1.7 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EGG12463.1 - 9.6e-10 38.6 0.0 3e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EGG12463.1 - 2.1e-07 31.0 0.2 5.9e-07 29.5 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EGG12463.1 - 0.025 14.1 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Metallophos_3 PF14582.1 EGG12463.1 - 0.045 12.9 0.1 0.085 11.9 0.1 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Ribosomal_L37 PF08561.5 EGG12463.1 - 0.086 12.4 0.1 0.44 10.1 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 AAA_23 PF13476.1 EGG12463.1 - 0.19 12.0 0.0 0.19 12.0 0.0 3.4 3 1 0 4 4 4 0 AAA domain ABC_tran PF00005.22 EGG12464.1 - 9.7e-47 158.7 0.0 9e-25 87.5 0.1 2.8 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EGG12464.1 - 1.4e-22 79.3 4.9 1.4e-22 79.3 3.4 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EGG12464.1 - 2.7e-18 66.9 4.9 2.2e-05 24.6 0.0 4.5 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 EGG12464.1 - 4.6e-09 35.8 2.7 2.3e-06 27.0 0.7 4.3 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EGG12464.1 - 8.1e-08 32.4 0.1 0.12 12.4 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EGG12464.1 - 4.7e-07 29.2 0.1 0.0076 15.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 EGG12464.1 - 5.4e-07 29.4 0.1 0.016 14.9 0.0 3.4 2 1 0 3 3 3 2 NACHT domain MMR_HSR1 PF01926.18 EGG12464.1 - 6e-06 26.2 0.1 0.1 12.5 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EGG12464.1 - 1.1e-05 25.0 0.0 0.51 9.7 0.0 3.3 3 0 0 3 3 3 2 AAA-like domain Miro PF08477.8 EGG12464.1 - 2e-05 25.0 0.0 0.45 11.0 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein DUF258 PF03193.11 EGG12464.1 - 3.6e-05 23.0 0.1 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EGG12464.1 - 4.9e-05 23.1 0.8 0.021 14.7 0.1 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EGG12464.1 - 9.8e-05 23.1 0.1 0.34 11.7 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.1 EGG12464.1 - 0.00012 21.2 1.0 2.3 7.1 0.0 3.6 3 1 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 EGG12464.1 - 0.00023 21.0 0.1 0.61 10.0 0.0 3.3 4 0 0 4 4 3 1 AAA domain ArgK PF03308.11 EGG12464.1 - 0.00026 19.8 0.0 0.12 11.0 0.0 2.4 2 0 0 2 2 2 2 ArgK protein RNA_helicase PF00910.17 EGG12464.1 - 0.0013 18.8 0.0 0.46 10.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EGG12464.1 - 0.0017 18.2 0.0 0.49 10.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGG12464.1 - 0.0023 17.3 0.0 1.3 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EGG12464.1 - 0.0045 16.7 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EGG12464.1 - 0.0055 17.0 11.0 0.12 12.6 0.0 3.9 3 1 1 4 4 4 1 AAA domain AAA PF00004.24 EGG12464.1 - 0.0061 16.7 0.0 0.66 10.1 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGG12464.1 - 0.0065 16.4 2.3 0.9 9.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EGG12464.1 - 0.0077 16.5 1.7 5.7 7.2 0.0 4.2 5 0 0 5 5 4 0 AAA domain AAA_16 PF13191.1 EGG12464.1 - 0.0099 15.8 9.5 0.39 10.6 0.3 3.5 3 2 0 3 3 2 2 AAA ATPase domain Dynamin_N PF00350.18 EGG12464.1 - 0.021 14.6 1.2 1.1 9.0 0.0 3.3 3 1 0 3 3 3 0 Dynamin family AAA_5 PF07728.9 EGG12464.1 - 0.024 14.3 0.5 13 5.5 0.1 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EGG12464.1 - 0.032 14.0 3.6 0.64 9.7 0.0 3.2 4 0 0 4 4 3 0 Domain of unknown function DUF87 NTPase_1 PF03266.10 EGG12464.1 - 0.065 12.9 0.0 8 6.1 0.0 2.6 2 0 0 2 2 2 0 NTPase MutS_V PF00488.16 EGG12464.1 - 0.08 12.3 0.0 7.5 5.8 0.0 2.3 2 0 0 2 2 2 0 MutS domain V cobW PF02492.14 EGG12464.1 - 0.086 12.2 0.3 2.7 7.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EGG12464.1 - 0.16 11.4 1.1 4.3 6.7 0.0 2.5 3 0 0 3 3 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EGG12464.1 - 6.3 6.4 8.5 7.3 6.2 0.0 3.3 4 1 0 4 4 4 0 Archaeal ATPase OPT PF03169.10 EGG12465.1 - 1.3e-43 149.4 24.8 3.9e-32 111.4 3.7 4.7 3 1 1 4 4 4 3 OPT oligopeptide transporter protein PMEI PF04043.10 EGG12466.1 - 0.024 14.5 1.1 0.026 14.4 0.8 1.1 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Cyt-b5 PF00173.23 EGG12468.1 - 0.00026 20.7 0.1 0.00034 20.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DIM1 PF02966.11 EGG12469.1 - 1.6e-63 212.1 0.0 1.8e-63 211.9 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EGG12469.1 - 0.00022 20.8 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGG12469.1 - 0.015 15.3 0.1 0.027 14.6 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.1 EGG12469.1 - 0.042 13.8 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like PCMT PF01135.14 EGG12475.1 - 2.2e-60 203.8 0.0 3.3e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EGG12475.1 - 1.3e-05 25.2 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG12475.1 - 8.7e-05 22.2 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG12475.1 - 0.0011 19.5 0.0 0.0024 18.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EGG12475.1 - 0.0023 17.3 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.1 EGG12475.1 - 0.0028 17.2 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PIG-S PF10510.4 EGG12477.1 - 2.1e-108 363.2 10.6 8.5e-107 357.9 7.3 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein OPT PF03169.10 EGG12478.1 - 4.6e-114 382.1 32.3 5.2e-107 358.8 16.7 2.0 2 0 0 2 2 2 2 OPT oligopeptide transporter protein RloB PF13707.1 EGG12479.1 - 0.016 14.9 0.7 0.027 14.1 0.5 1.5 1 0 0 1 1 1 0 RloB-like protein Phtf-FEM1B_bdg PF12129.3 EGG12479.1 - 0.071 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor AAA_12 PF13087.1 EGG12479.1 - 0.13 11.6 0.8 0.22 10.8 0.6 1.3 1 0 0 1 1 1 0 AAA domain Utp21 PF04192.7 EGG12481.1 - 1e-52 178.6 0.0 1.5e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EGG12481.1 - 1.8e-19 68.8 14.0 1.7e-06 27.6 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGG12481.1 - 5e-05 22.2 0.0 0.31 9.7 0.0 3.2 3 0 0 3 3 3 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 EGG12481.1 - 0.0073 15.1 0.0 0.52 9.0 0.0 2.4 2 1 0 3 3 3 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 EGG12481.1 - 0.027 12.7 0.0 0.093 11.0 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF3421 PF11901.3 EGG12482.1 - 3.5e-23 81.6 8.0 1.4e-13 50.6 1.2 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF3421) DUF4366 PF14283.1 EGG12482.1 - 0.0039 16.6 0.4 0.0075 15.7 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) CBM_5_12 PF02839.9 EGG12482.1 - 0.049 13.2 3.5 0.16 11.6 2.4 1.9 1 0 0 1 1 1 0 Carbohydrate binding domain APC_CDC26 PF10471.4 EGG12483.1 - 0.74 10.5 8.3 0.8 10.4 5.8 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF1645 PF07816.6 EGG12483.1 - 3.5 8.0 7.9 3.4 8.0 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) DUF999 PF06198.6 EGG12483.1 - 6.7 6.4 10.0 7.4 6.3 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF999) PROCN PF08083.6 EGG12488.1 - 2.7e-112 375.2 2.7 3.2e-112 375.0 1.9 1.0 1 0 0 1 1 1 1 PROCN (NUC071) domain RVT_3 PF13456.1 EGG12488.1 - 0.025 14.3 0.3 0.098 12.4 0.1 1.9 1 1 1 2 2 2 0 Reverse transcriptase-like U5_2-snRNA_bdg PF10597.4 EGG12489.1 - 1.2e-18 66.9 0.2 5.8e-17 61.5 0.1 2.2 1 1 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 AF1Q PF15017.1 EGG12494.1 - 0.45 10.4 15.3 0.034 14.0 7.1 1.7 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator EBV-NA3 PF05009.7 EGG12494.1 - 1.6 7.9 4.6 2.5 7.3 3.2 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) GCIP PF13324.1 EGG12494.1 - 2.8 7.0 5.5 4.4 6.4 3.8 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.5 EGG12494.1 - 7.2 6.9 12.5 12 6.2 8.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EGG12494.1 - 7.9 5.6 6.8 13 4.9 4.7 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EGG12494.1 - 8.3 5.9 15.1 9.2 5.7 8.9 1.8 2 0 0 2 2 2 0 Nucleoplasmin RhoGAP PF00620.22 EGG12495.1 - 1.6e-38 131.6 0.4 5.1e-38 130.0 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EGG12495.1 - 6.4e-27 93.4 35.9 5.1e-12 45.6 2.2 5.4 6 0 0 6 6 6 4 LIM domain OMPdecase PF00215.19 EGG12497.1 - 9e-76 254.2 0.0 1.1e-75 253.8 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF1940 PF09155.5 EGG12497.1 - 0.1 12.4 0.1 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) Dehydrin PF00257.14 EGG12498.1 - 7.8 6.8 12.2 2.6 8.3 2.0 3.1 3 0 0 3 3 3 0 Dehydrin F-box PF00646.28 EGG12500.1 - 0.079 12.6 3.9 2.8 7.7 0.2 3.6 3 0 0 3 3 3 0 F-box domain Exo_endo_phos PF03372.18 EGG12502.1 - 4.6e-26 92.2 0.1 6.4e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EGG12502.1 - 8.6e-19 66.7 4.0 5.2e-10 38.7 0.4 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG12502.1 - 7e-09 35.3 3.4 3.4e-07 29.9 0.4 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 EGG12502.1 - 4.3e-08 32.0 5.5 0.056 13.6 0.0 5.0 4 0 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 EGG12502.1 - 1.6e-07 30.3 1.9 0.55 10.4 0.0 5.1 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 EGG12502.1 - 0.021 14.8 0.3 1.4 9.2 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat Exo_endo_phos_2 PF14529.1 EGG12502.1 - 0.043 13.4 0.0 0.62 9.6 0.0 2.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase RVT_3 PF13456.1 EGG12504.1 - 0.014 15.2 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like TMEM238 PF15125.1 EGG12504.1 - 0.21 11.5 1.6 0.48 10.3 1.1 1.5 1 0 0 1 1 1 0 TMEM238 protein family RasGEF PF00617.14 EGG12505.1 - 1.2e-39 135.9 0.0 2.4e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGG12505.1 - 1.1e-06 28.6 0.4 7.1e-06 26.0 0.3 2.4 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EGG12505.1 - 7.1e-05 23.2 0.0 0.00023 21.6 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 EGG12505.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Aldedh PF00171.17 EGG12507.1 - 3.8e-127 424.4 0.1 4.3e-127 424.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGG12507.1 - 0.0097 14.6 0.0 0.016 13.9 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Mito_carr PF00153.22 EGG12508.1 - 4.4e-44 148.1 1.5 1.1e-15 57.0 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein UCH PF00443.24 EGG12509.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Asn_synthase PF00733.16 EGG12510.1 - 7.6e-49 166.5 0.0 1.2e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGG12510.1 - 1.8e-09 37.3 0.0 4.6e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain SET PF00856.23 EGG12510.1 - 3e-09 37.3 0.1 8.6e-09 35.8 0.1 1.8 1 1 0 1 1 1 1 SET domain GATase_6 PF13522.1 EGG12510.1 - 6.3e-06 26.1 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EGG12510.1 - 0.23 10.6 0.0 0.44 9.7 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein HA2 PF04408.18 EGG12511.1 - 2.1e-25 88.6 0.0 2.1e-25 88.6 0.0 3.3 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGG12511.1 - 1.2e-23 83.1 0.0 3.2e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGG12511.1 - 5.9e-13 48.4 0.0 3.2e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGG12511.1 - 2.2e-05 24.0 0.0 7.2e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EGG12511.1 - 0.00028 19.8 0.0 0.00065 18.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EGG12511.1 - 0.00032 20.8 0.0 0.0015 18.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGG12511.1 - 0.026 14.2 0.5 0.38 10.5 0.2 2.4 2 0 0 2 2 2 0 Part of AAA domain SRP54 PF00448.17 EGG12511.1 - 0.033 13.6 0.2 0.11 11.8 0.0 2.0 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain DUF3074 PF11274.3 EGG12512.1 - 7.6e-32 110.4 0.1 1.6e-31 109.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) ParA PF10609.4 EGG12513.1 - 1.7e-29 101.5 0.0 3.3e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGG12513.1 - 3.4e-10 39.6 0.0 8.3e-10 38.3 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EGG12513.1 - 8e-07 28.4 0.0 6e-05 22.2 0.0 2.2 1 1 1 2 2 2 2 ATPase MipZ AAA_31 PF13614.1 EGG12513.1 - 3.6e-05 23.7 0.0 0.00013 21.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EGG12513.1 - 0.00025 20.1 1.0 0.00051 19.1 0.2 1.9 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EGG12513.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGG12513.1 - 0.11 12.2 2.2 0.39 10.5 0.1 2.6 3 0 0 3 3 3 0 Part of AAA domain LRR_1 PF00560.28 EGG12514.1 - 7.3e-09 34.4 5.8 2.8 8.3 0.1 6.3 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_4 PF12799.2 EGG12514.1 - 2.5e-07 30.1 5.3 0.001 18.6 0.2 3.9 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG12514.1 - 2e-06 27.4 1.4 0.00077 19.1 0.0 3.5 4 0 0 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 EGG12514.1 - 0.00012 21.7 1.9 3.7 8.1 0.1 5.5 5 1 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EGG12514.1 - 0.017 15.1 2.5 5.2 7.4 0.1 4.3 4 1 0 4 4 4 0 Leucine Rich repeat DUF1798 PF08807.5 EGG12515.1 - 0.11 12.2 0.2 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Rib_5-P_isom_A PF06026.9 EGG12519.1 - 6e-10 38.6 0.0 7.6e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) VLPT PF07122.6 EGG12521.1 - 0.098 12.3 0.8 0.17 11.5 0.5 1.4 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) Arrestin_N PF00339.24 EGG12522.1 - 0.08 12.7 0.2 0.43 10.3 0.1 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain AAA PF00004.24 EGG12523.1 - 2.7e-50 169.9 0.0 6.2e-41 139.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGG12523.1 - 2.8e-08 33.9 0.1 7.5e-06 26.0 0.0 3.2 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 EGG12523.1 - 7.8e-08 32.5 0.5 0.0013 18.8 0.0 4.4 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EGG12523.1 - 8.8e-08 31.7 0.0 3e-05 23.5 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_2 PF07724.9 EGG12523.1 - 2.4e-05 24.3 0.0 9.5e-05 22.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EGG12523.1 - 3e-05 23.7 0.0 0.0074 16.0 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGG12523.1 - 4.6e-05 24.2 3.0 0.021 15.6 0.0 4.2 4 0 0 4 4 3 1 AAA domain Sigma54_activ_2 PF14532.1 EGG12523.1 - 4.9e-05 23.4 0.0 0.23 11.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 EGG12523.1 - 0.0001 22.2 0.0 0.052 13.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EGG12523.1 - 0.00013 21.6 0.0 0.0065 16.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EGG12523.1 - 0.00048 20.2 0.0 0.055 13.6 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EGG12523.1 - 0.0014 18.4 0.0 0.013 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EGG12523.1 - 0.0019 18.4 0.1 0.084 13.1 0.0 3.0 3 0 0 3 3 2 1 ABC transporter AAA_18 PF13238.1 EGG12523.1 - 0.0022 18.2 3.3 0.045 14.0 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.1 EGG12523.1 - 0.0054 16.1 0.1 0.025 13.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGG12523.1 - 0.0082 16.1 0.0 0.076 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EGG12523.1 - 0.011 14.9 0.1 0.085 12.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EGG12523.1 - 0.013 14.9 0.0 0.9 8.9 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.11 EGG12523.1 - 0.016 14.4 0.0 0.059 12.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.8 EGG12523.1 - 0.027 13.2 0.0 0.049 12.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_30 PF13604.1 EGG12523.1 - 0.031 13.8 0.0 0.08 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGG12523.1 - 0.063 12.9 0.1 0.41 10.2 0.0 2.4 2 1 0 2 2 2 0 NACHT domain RuvB_N PF05496.7 EGG12523.1 - 0.08 11.9 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 EGG12523.1 - 0.084 11.7 0.0 0.32 9.8 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EGG12523.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DS PF01916.12 EGG12523.1 - 0.5 9.4 0.8 1 8.4 0.5 1.4 1 0 0 1 1 1 0 Deoxyhypusine synthase HECT PF00632.20 EGG12524.1 - 5.4e-77 259.0 0.0 6.7e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Es2 PF09751.4 EGG12527.1 - 8.7e-65 219.7 9.5 1.4e-64 219.0 6.6 1.3 1 0 0 1 1 1 1 Nuclear protein Es2 Amidohydro_1 PF01979.15 EGG12528.1 - 0.00047 19.9 0.0 0.03 13.9 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family CHZ PF09649.5 EGG12529.1 - 0.87 8.8 5.7 0.72 9.1 1.4 2.3 2 0 0 2 2 2 0 Histone chaperone domain CHZ Ribosomal_L27e PF01777.13 EGG12532.1 - 6.3e-38 128.7 0.7 8.3e-38 128.3 0.5 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EGG12532.1 - 0.00012 21.6 0.7 0.00034 20.2 0.5 1.8 1 0 0 1 1 1 1 KOW motif Phage_portal PF04860.7 EGG12532.1 - 0.058 12.0 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein LIM PF00412.17 EGG12533.1 - 6.1e-16 58.2 38.9 4.7e-08 32.9 1.6 5.4 5 1 0 5 5 5 4 LIM domain TRIC PF05197.8 EGG12534.1 - 0.0089 15.4 0.3 0.016 14.6 0.2 1.4 1 0 0 1 1 1 1 TRIC channel Abhydrolase_6 PF12697.2 EGG12535.1 - 3.3e-32 112.2 0.0 7.8e-32 110.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGG12535.1 - 3e-11 43.2 0.0 5.6e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGG12535.1 - 7.1e-11 42.1 0.0 1.5e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold CMD PF02627.15 EGG12535.1 - 8.4e-08 31.9 0.0 2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Esterase PF00756.15 EGG12535.1 - 5.7e-05 22.6 0.0 9.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.8 EGG12535.1 - 0.0028 17.1 0.0 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 EGG12535.1 - 0.0034 17.1 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase TIMELESS PF04821.9 EGG12538.1 - 3.1e-26 92.2 2.5 3.6e-14 52.6 0.3 3.2 2 1 1 3 3 3 2 Timeless protein ERCC4 PF02732.10 EGG12539.1 - 2e-27 95.6 0.1 7.8e-27 93.7 0.0 2.1 2 0 0 2 2 2 1 ERCC4 domain F-box PF00646.28 EGG12541.1 - 0.62 9.7 7.9 0.75 9.5 0.0 4.0 4 0 0 4 4 4 0 F-box domain PH PF00169.24 EGG12542.1 - 4.9e-12 45.9 0.9 1.9e-11 44.0 0.2 2.3 2 0 0 2 2 2 1 PH domain FCH PF00611.18 EGG12542.1 - 0.049 13.8 1.1 0.28 11.3 0.0 2.7 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain Aconitase PF00330.15 EGG12545.1 - 5.1e-176 585.7 0.2 1.3e-175 584.4 0.1 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGG12545.1 - 1.2e-43 148.3 0.0 2.4e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain CHZ PF09649.5 EGG12546.1 - 2.6e-15 55.3 3.7 2.6e-15 55.3 2.6 2.3 3 0 0 3 3 3 1 Histone chaperone domain CHZ Helicase_C PF00271.26 EGG12548.1 - 3.4e-05 23.6 0.0 6.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUKH_5 PF14567.1 EGG12548.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Tetraspannin PF00335.15 EGG12549.1 - 5.9e-11 42.0 5.9 5.9e-11 42.0 4.1 2.2 3 0 0 3 3 3 1 Tetraspanin family RhaT PF06379.7 EGG12549.1 - 0.018 14.0 1.4 0.027 13.4 0.9 1.2 1 0 0 1 1 1 0 L-rhamnose-proton symport protein (RhaT) TMEM220 PF15071.1 EGG12549.1 - 0.091 13.2 0.2 0.23 11.9 0.1 1.6 1 0 0 1 1 1 0 Transmembrane family 220, helix HIF-1a_CTAD PF08778.5 EGG12550.1 - 0.01 15.2 0.1 0.022 14.2 0.1 1.5 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain MAS20 PF02064.10 EGG12551.1 - 5.8e-20 71.4 0.4 2.1e-19 69.6 0.3 1.9 1 1 0 1 1 1 1 MAS20 protein import receptor OAD_gamma PF04277.8 EGG12551.1 - 0.43 10.9 0.0 0.43 10.9 0.0 4.0 3 2 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain WH2 PF02205.15 EGG12553.1 - 2.7e-05 23.6 2.2 0.0001 21.8 0.3 2.3 2 0 0 2 2 2 1 WH2 motif OmdA PF13376.1 EGG12556.1 - 0.15 11.7 0.3 0.15 11.7 0.2 2.0 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Ycf1 PF05758.7 EGG12556.1 - 1.4 6.5 5.9 1.3 6.6 4.1 1.0 1 0 0 1 1 1 0 Ycf1 DUF2951 PF11166.3 EGG12556.1 - 1.4 8.8 8.7 1.8 8.4 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) HSP70 PF00012.15 EGG12556.1 - 2.2 6.0 7.2 2.3 6.0 5.0 1.0 1 0 0 1 1 1 0 Hsp70 protein Myb_DNA-bind_3 PF12776.2 EGG12557.1 - 0.00018 22.0 0.0 0.00032 21.2 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain FA_desaturase PF00487.19 EGG12558.1 - 3e-24 85.8 23.1 1.4e-23 83.6 16.0 1.9 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EGG12558.1 - 1.5e-05 25.0 0.0 4.5e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) LON PF02190.11 EGG12559.1 - 5e-21 75.3 0.1 1.6e-20 73.6 0.0 1.8 1 1 1 2 2 2 1 ATP-dependent protease La (LON) domain zf-C3HC4_3 PF13920.1 EGG12559.1 - 3.5e-07 29.7 5.8 3.5e-07 29.7 4.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG12559.1 - 3.6e-07 30.0 14.8 1.2e-06 28.4 6.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGG12559.1 - 4e-07 29.7 8.6 4e-07 29.7 5.9 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EGG12559.1 - 1.6e-06 27.7 14.9 3.4e-06 26.6 5.6 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGG12559.1 - 4.8e-06 26.1 7.6 4.8e-06 26.1 5.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGG12559.1 - 3.1e-05 23.7 9.2 0.00011 22.0 4.1 2.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGG12559.1 - 3.2e-05 23.5 10.9 0.013 15.1 0.5 3.6 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_4 PF14570.1 EGG12559.1 - 0.00085 18.8 7.3 0.0019 17.7 1.8 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EGG12559.1 - 0.0028 17.3 3.5 0.0061 16.3 2.4 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EGG12559.1 - 0.0036 17.3 1.7 0.0036 17.3 1.2 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger zf-Nse PF11789.3 EGG12559.1 - 0.014 14.8 10.0 0.057 12.9 3.1 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EGG12559.1 - 0.087 12.6 0.9 0.23 11.3 0.7 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EGG12559.1 - 0.17 11.4 9.2 0.047 13.2 2.2 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 EGG12559.1 - 0.4 10.1 7.2 0.48 9.9 3.8 2.1 2 0 0 2 2 2 0 P-11 zinc finger Elf1 PF05129.8 EGG12559.1 - 2.8 7.7 7.4 0.85 9.3 1.6 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Homeobox_KN PF05920.6 EGG12562.1 - 2e-16 59.4 0.3 2e-16 59.4 0.2 2.6 3 0 0 3 3 3 1 Homeobox KN domain Homeobox PF00046.24 EGG12562.1 - 1.3e-05 24.7 0.2 2.9e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EGG12562.1 - 0.12 11.4 0.0 0.27 10.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Trypan_PARP PF05887.6 EGG12563.1 - 3 7.6 6.6 3.5 7.4 4.6 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PNGaseA PF12222.3 EGG12564.1 - 6.8e-72 242.6 0.0 1.6e-71 241.4 0.0 1.5 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Septin PF00735.13 EGG12565.1 - 3.8e-35 121.2 0.4 7.1e-16 58.0 0.1 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.18 EGG12565.1 - 0.0024 17.7 0.4 0.014 15.3 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGG12565.1 - 0.0039 16.3 0.1 0.0083 15.2 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EGG12565.1 - 0.041 14.3 0.1 0.49 10.8 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein DUF3519 PF12033.3 EGG12565.1 - 0.044 13.9 0.5 0.093 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) Pox_A32 PF04665.7 EGG12565.1 - 0.067 12.4 0.1 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein Dynamin_N PF00350.18 EGG12565.1 - 0.085 12.6 1.0 0.21 11.3 0.7 1.7 1 1 0 1 1 1 0 Dynamin family Aldo_ket_red PF00248.16 EGG12566.1 - 1.2e-52 178.5 0.0 1.4e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ENTH PF01417.15 EGG12568.1 - 9.8e-47 157.9 0.3 1.5e-46 157.3 0.2 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EGG12568.1 - 4.9e-05 22.1 0.1 7.9e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 ANTH domain DUF3542 PF12061.3 EGG12568.1 - 0.049 12.6 0.0 0.067 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3542) MOR2-PAG1_C PF14225.1 EGG12568.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Cell morphogenesis C-terminal POT1 PF02765.12 EGG12569.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 EGG12569.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain PLA2_B PF01735.13 EGG12571.1 - 2e-29 102.0 0.0 2.5e-28 98.4 0.0 2.2 1 1 0 1 1 1 1 Lysophospholipase catalytic domain E1-N PF14463.1 EGG12571.1 - 0.052 13.1 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 E1 N-terminal domain SNARE PF05739.14 EGG12572.1 - 5.5e-20 70.8 2.9 5.5e-20 70.8 2.0 3.3 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 EGG12572.1 - 1.7e-05 24.9 14.0 1.7e-05 24.9 9.7 3.2 1 1 2 3 3 3 1 Syntaxin Cyc-maltodext_N PF09087.6 EGG12572.1 - 0.08 12.8 1.1 0.2 11.5 0.8 1.7 1 0 0 1 1 1 0 Cyclomaltodextrinase, N-terminal Ste5_C PF12194.3 EGG12572.1 - 0.11 12.0 3.9 1.7 8.2 0.0 2.8 2 1 0 2 2 2 0 Protein kinase Fus3-binding CCDC-167 PF15188.1 EGG12572.1 - 0.21 11.5 3.7 0.27 11.1 0.6 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 OAD_gamma PF04277.8 EGG12572.1 - 0.23 11.8 3.0 0.49 10.7 0.0 2.6 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain GlutR_dimer PF00745.15 EGG12572.1 - 0.34 10.8 3.9 0.31 10.9 0.3 2.4 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain vMSA PF00695.14 EGG12572.1 - 0.88 8.6 7.2 0.26 10.4 0.2 2.1 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus DUF4463 PF14703.1 EGG12572.1 - 1.9 9.0 6.2 6.7 7.3 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4463) Alpha-2-MRAP_C PF06401.6 EGG12572.1 - 2.2 8.1 12.5 1 9.1 2.7 2.6 1 1 2 3 3 3 0 Alpha-2-macroglobulin RAP, C-terminal domain Helicase_C PF00271.26 EGG12574.1 - 1.6e-08 34.3 0.0 3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EGG12575.1 - 1e-07 31.7 0.0 1.7e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold CDC45 PF02724.9 EGG12576.1 - 0.0066 14.5 7.7 0.0077 14.3 5.3 1.1 1 0 0 1 1 1 1 CDC45-like protein SRA1 PF07304.6 EGG12576.1 - 0.039 13.6 0.0 0.039 13.6 0.0 2.2 2 1 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Cas_Csn2 PF09711.5 EGG12576.1 - 0.061 13.0 0.3 0.082 12.5 0.2 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) NOA36 PF06524.7 EGG12576.1 - 0.36 10.0 4.5 0.53 9.4 3.1 1.3 1 0 0 1 1 1 0 NOA36 protein Macoilin PF09726.4 EGG12576.1 - 7.6 4.6 11.8 8.7 4.4 8.2 1.1 1 0 0 1 1 1 0 Transmembrane protein adh_short PF00106.20 EGG12577.1 - 1.4e-21 77.0 0.0 7.7e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGG12577.1 - 1.2e-06 28.2 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGG12577.1 - 3.9e-05 23.5 0.0 5.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGG12577.1 - 0.00066 19.7 0.0 0.0014 18.6 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGG12577.1 - 0.0015 17.8 0.1 0.004 16.4 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family ApbA PF02558.11 EGG12577.1 - 0.048 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.10 EGG12577.1 - 0.074 11.9 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EGG12577.1 - 0.14 12.6 0.1 0.49 10.8 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF4061 PF13270.1 EGG12579.1 - 0.013 15.5 1.4 0.034 14.2 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) UBN2_2 PF14227.1 EGG12579.1 - 0.092 12.3 1.8 0.1 12.1 0.1 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type GUN4 PF05419.7 EGG12581.1 - 0.011 15.5 0.2 0.014 15.2 0.1 1.2 1 0 0 1 1 1 0 GUN4-like FAD_binding_3 PF01494.14 EGG12586.1 - 5.7e-23 81.5 0.0 1.4e-11 44.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EGG12586.1 - 6.9e-05 21.9 0.0 0.17 10.7 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 EGG12586.1 - 0.00083 18.3 0.0 0.014 14.3 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 EGG12586.1 - 0.0029 16.4 0.0 0.0045 15.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 EGG12586.1 - 0.012 16.0 0.1 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGG12586.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGG12586.1 - 0.034 14.0 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGG12586.1 - 0.04 12.5 0.0 0.45 9.0 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.1 EGG12586.1 - 0.09 12.8 1.1 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGG12586.1 - 0.17 10.9 0.1 0.33 9.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Iso_dh PF00180.15 EGG12587.1 - 1.9e-59 201.3 0.0 2.2e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GMC_oxred_N PF00732.14 EGG12590.1 - 1.3e-45 155.8 0.0 1.7e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGG12590.1 - 1.5e-37 129.1 0.0 3.1e-37 128.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase MMR1 PF08505.5 EGG12592.1 - 0.027 14.4 8.2 0.041 13.9 5.7 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein HMG_box PF00505.14 EGG12592.1 - 0.078 13.2 0.1 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 HMG (high mobility group) box Chalcone PF02431.10 EGG12593.1 - 0.0026 17.1 0.0 0.0053 16.1 0.0 1.5 1 1 0 1 1 1 1 Chalcone-flavanone isomerase Phage_GPD PF05954.6 EGG12594.1 - 0.14 11.3 0.9 0.18 10.9 0.6 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Alba PF01918.16 EGG12597.1 - 0.0019 17.7 0.1 0.14 11.7 0.1 3.0 2 1 0 2 2 2 1 Alba RB_A PF01858.12 EGG12597.1 - 0.05 13.2 0.5 0.079 12.6 0.3 1.4 1 1 0 1 1 1 0 Retinoblastoma-associated protein A domain DUF3605 PF12239.3 EGG12598.1 - 4.1e-16 59.2 1.0 3.9e-08 33.2 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3605) Trehalase PF01204.13 EGG12600.1 - 4.3e-20 71.8 0.4 4.7e-20 71.7 0.3 1.0 1 0 0 1 1 1 1 Trehalase UBN2_2 PF14227.1 EGG12602.1 - 2.1e-05 24.0 0.0 5.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EGG12602.1 - 2.2e-05 24.2 0.0 4.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type CFEM PF05730.6 EGG12603.1 - 2.1e-10 40.2 4.4 2.9e-10 39.8 3.1 1.2 1 0 0 1 1 1 1 CFEM domain SNF2_N PF00176.18 EGG12605.1 - 9.8e-30 103.3 0.1 1.2e-29 103.0 0.1 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGG12605.1 - 5.2e-07 29.2 0.0 6.5e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG12606.1 - 3.4e-07 30.0 0.1 6.8e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pyocin_S PF06958.7 EGG12607.1 - 0.26 11.6 2.3 0.37 11.1 1.6 1.2 1 0 0 1 1 1 0 S-type Pyocin Tic20 PF09685.5 EGG12608.1 - 0.067 13.1 2.9 0.094 12.6 2.0 1.1 1 0 0 1 1 1 0 Tic20-like protein Sec1 PF00995.18 EGG12609.1 - 3.8e-130 435.2 0.0 6.1e-130 434.5 0.0 1.3 1 1 0 1 1 1 1 Sec1 family Glycos_transf_4 PF00953.16 EGG12610.1 - 2.9e-31 108.4 10.2 2.9e-31 108.4 7.1 1.8 3 0 0 3 3 3 1 Glycosyl transferase family 4 DUF3312 PF11768.3 EGG12610.1 - 0.059 11.5 0.2 0.091 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Alg6_Alg8 PF03155.10 EGG12611.1 - 2.3e-96 323.4 32.9 6.3e-74 249.5 10.7 2.8 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family mRNA_triPase PF02940.10 EGG12612.1 - 7.5e-42 143.5 0.2 7.5e-42 143.5 0.1 1.5 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain Rubis-subs-bind PF09273.6 EGG12613.1 - 0.0047 16.8 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding MBOAT_2 PF13813.1 EGG12614.1 - 1.2e-12 47.6 0.4 6e-12 45.4 0.3 2.2 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ERG4_ERG24 PF01222.12 EGG12616.1 - 1.9e-139 464.9 18.6 2.3e-139 464.6 12.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGG12616.1 - 4.4e-07 29.4 0.4 7.5e-07 28.6 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EGG12616.1 - 2.1e-05 24.5 3.4 2.7e-05 24.2 0.0 3.0 4 0 0 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.9 EGG12616.1 - 0.017 15.2 1.0 0.052 13.7 0.0 2.3 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF383 PF04063.9 EGG12617.1 - 6.6e-53 179.1 0.0 9.5e-52 175.3 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EGG12617.1 - 2.3e-17 62.2 1.6 4.7e-17 61.3 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT_EZ PF13513.1 EGG12617.1 - 0.0094 16.4 1.0 0.4 11.2 0.0 3.3 3 0 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.1 EGG12617.1 - 0.012 15.9 0.7 0.1 12.9 0.1 2.8 2 2 0 2 2 2 0 HEAT repeats HEAT PF02985.17 EGG12617.1 - 0.033 14.2 0.0 0.18 11.9 0.0 2.3 1 0 0 1 1 1 0 HEAT repeat Ceramidase_alk PF04734.8 EGG12618.1 - 2.1e-234 779.3 0.0 2.4e-234 779.2 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase GPP34 PF05719.6 EGG12618.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) DUF77 PF01910.12 EGG12619.1 - 1.8e-33 114.0 0.0 2.1e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 EGG12619.1 - 0.06 13.5 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 YKOF-related Family Dus PF01207.12 EGG12619.1 - 0.092 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) STN PF07660.9 EGG12619.1 - 0.15 11.6 0.0 0.4 10.2 0.0 1.8 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain Solute_trans_a PF03619.11 EGG12620.1 - 2.2e-74 250.2 22.2 2.7e-74 249.9 15.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.6 EGG12620.1 - 6.5 6.6 8.3 0.91 9.4 0.9 2.7 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DAO PF01266.19 EGG12621.1 - 1.3e-27 96.6 0.1 1.9e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGG12621.1 - 1.8e-07 30.5 0.0 2.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGG12621.1 - 2.1e-05 23.5 0.9 3.1e-05 23.0 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGG12621.1 - 5.6e-05 23.1 0.0 0.00011 22.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGG12621.1 - 0.0023 18.3 0.3 0.0054 17.1 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGG12621.1 - 0.0027 16.2 1.7 0.0054 15.2 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EGG12621.1 - 0.0036 17.2 0.4 0.0068 16.4 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EGG12621.1 - 0.0047 15.8 0.1 0.0062 15.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EGG12621.1 - 0.0054 16.4 1.9 0.006 16.2 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EGG12621.1 - 0.033 13.3 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Fascin PF06268.8 EGG12621.1 - 0.036 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Fascin domain Lycopene_cycl PF05834.7 EGG12621.1 - 0.054 12.4 0.3 0.081 11.8 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF3255 PF11631.3 EGG12621.1 - 0.095 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) DUF3412 PF11892.3 EGG12621.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) zf-CSL PF05207.8 EGG12623.1 - 1.5e-16 59.6 1.3 3.2e-16 58.5 0.9 1.6 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EGG12623.1 - 5.2e-16 58.1 0.3 8.7e-16 57.4 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Lum_binding PF00677.12 EGG12623.1 - 0.029 14.2 0.2 0.067 13.0 0.2 1.6 1 1 0 1 1 1 0 Lumazine binding domain RA PF00788.18 EGG12623.1 - 0.1 13.0 0.1 0.39 11.2 0.0 1.9 1 1 1 2 2 2 0 Ras association (RalGDS/AF-6) domain UBN2 PF14223.1 EGG12625.1 - 1e-05 25.3 0.3 1.7e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EGG12625.1 - 4.1e-05 23.1 0.3 0.00053 19.5 0.2 2.2 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EGG12625.1 - 5.8e-05 22.6 0.2 0.0001 21.8 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF2462 PF09495.5 EGG12626.1 - 2.1e-10 41.1 4.6 2.1e-10 41.1 3.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Mem_trans PF03547.13 EGG12627.1 - 0.099 10.9 0.1 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Membrane transport protein Ndufs5 PF10200.4 EGG12629.1 - 0.016 15.1 4.8 0.03 14.2 3.4 1.6 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.8 EGG12629.1 - 0.038 13.9 6.2 1.6 8.7 0.1 2.4 1 1 1 2 2 2 0 CHCH domain DUF3128 PF11326.3 EGG12629.1 - 0.045 13.8 6.0 0.1 12.7 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Cmc1 PF08583.5 EGG12629.1 - 0.07 12.9 5.2 0.16 11.7 3.6 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 EGG12629.1 - 0.075 13.0 0.9 0.57 10.2 0.6 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.7 EGG12629.1 - 2.6 7.9 6.8 28 4.6 0.7 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) UCH PF00443.24 EGG12630.1 - 5.2e-50 170.0 0.0 9.3e-50 169.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGG12630.1 - 1.6e-05 24.5 20.5 4.8e-05 22.9 14.2 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EGG12631.1 - 5.1e-27 92.7 0.6 5.5e-12 45.0 0.0 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.1 EGG12631.1 - 0.004 17.3 0.1 27 5.2 0.0 3.9 4 0 0 4 4 4 2 PQQ-like domain Formyl_trans_C PF02911.13 EGG12631.1 - 0.012 15.7 0.1 0.06 13.4 0.0 2.2 3 0 0 3 3 3 0 Formyl transferase, C-terminal domain BBS2_Mid PF14783.1 EGG12631.1 - 0.11 12.3 0.7 2.1 8.1 0.0 3.1 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF1183 PF06682.7 EGG12632.1 - 2e-54 185.3 12.9 3.1e-53 181.4 9.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) CYSTM PF12734.2 EGG12632.1 - 0.0026 17.7 1.2 0.0061 16.6 0.9 1.6 1 0 0 1 1 1 1 Cysteine-rich TM module stress tolerance Serglycin PF04360.7 EGG12632.1 - 1.8 8.2 6.0 1.8 8.2 2.2 2.0 2 0 0 2 2 2 0 Serglycin CM_2 PF01817.16 EGG12633.1 - 8.1e-06 25.8 0.1 1.2e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Chorismate mutase type II Yip1 PF04893.12 EGG12635.1 - 8.4e-19 67.7 23.1 1.2e-18 67.1 16.0 1.2 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EGG12635.1 - 0.09 12.4 11.2 0.18 11.4 7.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) SH3_9 PF14604.1 EGG12636.1 - 9.1e-19 66.7 0.4 1.2e-10 40.8 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 EGG12636.1 - 1e-16 60.8 6.3 1e-16 60.8 0.1 2.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EGG12636.1 - 6.2e-12 44.7 0.1 3.5e-06 26.3 0.1 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 EGG12636.1 - 1.7e-11 43.6 4.3 2.7e-11 43.0 3.0 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 EGG12636.1 - 2.6e-11 42.8 0.1 2.2e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 EGG12636.1 - 1.3e-06 28.4 1.1 0.038 14.1 0.1 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain zf-RING-like PF08746.6 EGG12636.1 - 1.9 8.5 6.1 4.1 7.4 4.2 1.6 1 0 0 1 1 1 0 RING-like domain Vps5 PF09325.5 EGG12637.1 - 0.018 14.3 3.0 0.025 13.8 1.7 1.5 1 1 1 2 2 2 0 Vps5 C terminal like Fmp27_WPPW PF10359.4 EGG12637.1 - 0.048 12.0 4.1 0.05 12.0 2.8 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4428 PF14471.1 EGG12637.1 - 1.8 8.3 6.0 0.49 10.1 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) HNH_5 PF14279.1 EGG12637.1 - 3.3 7.7 6.3 19 5.3 0.2 2.4 1 1 1 2 2 2 0 HNH endonuclease DUF3774 PF12609.3 EGG12637.1 - 7.1 7.5 7.8 0.99 10.2 1.3 2.1 1 1 1 2 2 2 0 Wound-induced protein PSI_PsaE PF02427.12 EGG12638.1 - 0.025 13.9 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IV / PsaE Mad3_BUB1_I PF08311.7 EGG12640.1 - 1.1e-20 73.7 1.2 2.8e-20 72.3 0.7 1.8 1 1 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EGG12640.1 - 1.1e-17 64.0 0.0 2.5e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG12640.1 - 3e-06 26.4 0.0 6.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG12640.1 - 0.27 10.1 0.0 0.47 9.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Cellulase PF00150.13 EGG12641.1 - 5.8e-09 35.5 3.2 1.2e-07 31.2 2.2 2.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EGG12641.1 - 0.00011 22.6 0.0 0.00045 20.6 0.0 2.1 2 0 0 2 2 2 1 Sugar-binding cellulase-like KLRAQ PF10205.4 EGG12642.1 - 0.042 13.8 9.9 0.075 13.0 0.1 4.0 3 1 1 4 4 4 0 Predicted coiled-coil domain-containing protein TMF_DNA_bd PF12329.3 EGG12642.1 - 0.38 10.5 10.4 1.5 8.6 0.3 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EGG12642.1 - 2.9 7.7 17.7 3.9 7.3 2.7 2.6 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 EGG12642.1 - 6.4 6.5 6.8 7.6 6.3 0.2 3.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper Transp_cyt_pur PF02133.10 EGG12643.1 - 6.4e-126 420.4 41.0 1.4e-125 419.2 28.4 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin VIT1 PF01988.14 EGG12643.1 - 3.7 6.9 8.4 4 6.8 3.6 2.4 2 0 0 2 2 2 0 VIT family DUF4218 PF13960.1 EGG12644.1 - 2.7e-05 23.5 0.9 6.1e-05 22.4 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Gemini_C4 PF01492.12 EGG12646.1 - 0.046 13.4 4.4 0.12 12.0 3.0 1.7 1 0 0 1 1 1 0 Geminivirus C4 protein DNA_primase_lrg PF04104.9 EGG12647.1 - 6e-16 58.4 0.0 1.1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DNA_primase_lrg PF04104.9 EGG12648.1 - 3.7e-16 59.1 0.3 4.2e-16 58.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit TFCD_C PF12612.3 EGG12651.1 - 4.9e-19 68.5 4.9 7.2e-18 64.7 0.1 4.0 5 0 0 5 5 5 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 EGG12651.1 - 0.00013 22.1 1.7 0.41 10.9 0.0 4.9 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 EGG12651.1 - 0.00086 19.7 1.4 0.77 10.3 0.0 4.8 4 1 0 4 4 4 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGG12651.1 - 0.011 16.1 0.1 0.43 10.9 0.0 3.3 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EGG12651.1 - 0.014 15.3 8.1 0.34 11.1 0.0 6.1 8 0 0 8 8 8 0 HEAT repeat DUF4381 PF14316.1 EGG12651.1 - 0.029 14.4 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Elicitin PF00964.12 EGG12652.1 - 0.05 13.5 0.3 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 Elicitin Gly_transf_sug PF04488.10 EGG12653.1 - 3e-10 40.3 0.1 5.7e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Ribosomal_L10 PF00466.15 EGG12657.1 - 9e-25 86.5 0.4 3.8e-24 84.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EGG12657.1 - 1.5e-18 66.9 9.2 3.1e-18 65.9 4.7 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein S19 PF06756.6 EGG12657.1 - 0.15 11.9 0.5 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Chorion protein S19 C-terminal Glyoxalase PF00903.20 EGG12658.1 - 1.9e-18 66.6 0.1 2.6e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGG12658.1 - 1.1e-13 51.7 0.0 1.4e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EGG12658.1 - 5.5e-09 36.0 0.0 7.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EGG12658.1 - 0.01 15.7 0.0 0.017 14.9 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain CppA_N PF14506.1 EGG12658.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal YchF-GTPase_C PF06071.8 EGG12659.1 - 2.1e-36 123.5 0.4 4.4e-36 122.5 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EGG12659.1 - 2.5e-14 53.1 0.0 6e-14 51.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGG12659.1 - 6.1e-06 25.5 0.0 1.8e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_17 PF13207.1 EGG12659.1 - 0.012 16.4 0.1 0.049 14.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain BetaGal_dom3 PF13363.1 EGG12659.1 - 0.021 14.1 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 AAA_14 PF13173.1 EGG12659.1 - 0.085 12.7 0.0 0.62 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EGG12659.1 - 0.16 11.6 1.1 12 5.5 0.1 2.7 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Abhydrolase_5 PF12695.2 EGG12660.1 - 1.9e-06 27.7 0.1 0.00014 21.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGG12660.1 - 0.003 17.4 5.2 4.7 7.0 0.3 3.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGG12660.1 - 0.013 15.3 0.0 0.036 13.9 0.0 1.8 1 1 0 1 1 1 0 Putative lysophospholipase Abhydrolase_1 PF00561.15 EGG12660.1 - 0.016 14.8 1.7 0.44 10.0 0.0 2.7 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF427 PF04248.7 EGG12661.1 - 3.6e-26 90.6 0.3 4.1e-26 90.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) adh_short_C2 PF13561.1 EGG12662.1 - 1.1e-32 113.7 0.0 1.3e-32 113.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGG12662.1 - 3.1e-20 72.7 0.1 4.1e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG12662.1 - 5.4e-10 39.2 0.0 7.2e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 KR domain PA PF02225.17 EGG12662.1 - 0.0019 17.8 0.0 0.037 13.7 0.0 2.4 2 0 0 2 2 2 1 PA domain Polysacc_synt_2 PF02719.10 EGG12662.1 - 0.0058 15.5 0.0 0.008 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SPC25 PF06703.6 EGG12663.1 - 3.8e-34 117.5 0.9 4.6e-34 117.3 0.6 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Gly_transf_sug PF04488.10 EGG12664.1 - 4.6e-06 26.9 0.1 4.4e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Cyt_c_ox_IV PF12270.3 EGG12665.1 - 0.03 14.0 0.3 0.088 12.5 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Tcp11 PF05794.8 EGG12667.1 - 2.1e-63 214.5 0.0 3.5e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 T-complex protein 11 GalP_UDP_transf PF01087.17 EGG12670.1 - 3.5e-60 203.2 0.1 5.1e-60 202.6 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EGG12670.1 - 6.9e-43 146.0 0.0 1.5e-42 144.9 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DIE2_ALG10 PF04922.7 EGG12671.1 - 1.5e-97 327.0 20.5 7.7e-97 324.6 14.2 1.9 1 1 0 1 1 1 1 DIE2/ALG10 family Tantalus PF15386.1 EGG12672.1 - 5 6.9 7.6 0.31 10.8 0.5 2.4 2 0 0 2 2 2 0 Drosophila Tantalus-like Tantalus PF15386.1 EGG12674.1 - 8.3 6.2 7.9 0.42 10.3 0.3 2.5 3 0 0 3 3 3 0 Drosophila Tantalus-like LNP1 PF15419.1 EGG12677.1 - 0.11 12.5 1.9 0.16 12.0 0.5 1.8 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 TrbI_Ftype PF09677.5 EGG12677.1 - 0.16 11.7 0.3 7.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) 4HBT PF03061.17 EGG12678.1 - 3.4e-11 43.1 0.0 5.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily LEA_3 PF03242.8 EGG12678.1 - 0.15 12.2 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein HD_3 PF13023.1 EGG12679.1 - 1.5e-44 151.6 0.1 1.9e-44 151.2 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EGG12679.1 - 3.3e-06 27.1 0.8 2.3e-05 24.4 0.6 2.0 1 1 0 1 1 1 1 HD domain Pectinesterase PF01095.14 EGG12680.1 - 9.5e-39 132.7 1.5 1.4e-38 132.1 1.0 1.1 1 0 0 1 1 1 1 Pectinesterase PGM_PMM_II PF02879.11 EGG12681.1 - 0.033 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Phosphodiest PF01663.17 EGG12682.1 - 1.5e-70 238.3 0.8 1.9e-70 238.0 0.6 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGG12682.1 - 0.017 14.3 0.1 0.84 8.7 0.0 2.3 2 0 0 2 2 2 0 Sulfatase Ldl_recept_a PF00057.13 EGG12684.1 - 0.28 11.1 5.1 0.16 11.9 2.5 1.4 1 1 0 1 1 1 0 Low-density lipoprotein receptor domain class A ADK PF00406.17 EGG12685.1 - 7.7e-43 145.9 0.0 2.8e-42 144.1 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase ADK_lid PF05191.9 EGG12685.1 - 1.2e-14 53.6 0.0 3.1e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EGG12685.1 - 5.7e-05 23.0 0.0 0.0023 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGG12685.1 - 8.9e-05 23.2 0.0 0.00021 22.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG12685.1 - 0.0012 19.1 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGG12685.1 - 0.049 12.7 0.1 0.085 12.0 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PARP_reg PF02877.9 EGG12686.1 - 0.22 11.1 7.4 0.21 11.2 0.7 2.4 1 1 1 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Anemone_cytotox PF06369.7 EGG12687.1 - 0.07 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Sea anemone cytotoxic protein OPA3 PF07047.7 EGG12688.1 - 2.6e-32 111.3 0.3 4.2e-32 110.7 0.1 1.3 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) HLH PF00010.21 EGG12688.1 - 0.024 14.3 0.1 0.045 13.4 0.1 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Cellulase PF00150.13 EGG12689.1 - 2.3e-12 46.6 0.0 9.5e-08 31.5 0.0 2.9 3 0 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 EGG12689.1 - 0.0089 15.4 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_14 PF01373.12 EGG12689.1 - 0.036 12.8 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 Histone PF00125.19 EGG12690.1 - 5.4e-31 106.5 0.4 8.6e-31 105.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGG12690.1 - 7.9e-05 22.7 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGG12690.1 - 0.002 18.1 0.1 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PRAI PF00697.17 EGG12690.1 - 0.053 13.0 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Bromo_TP PF07524.8 EGG12690.1 - 0.056 13.1 0.1 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 EGG12690.1 - 0.11 12.2 0.2 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Methyltransf_PK PF05891.7 EGG12691.1 - 2.1e-51 174.3 0.0 2.3e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 EGG12691.1 - 5.5e-07 30.1 0.0 8.7e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG12691.1 - 0.00011 22.4 0.0 0.00019 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG12691.1 - 0.00017 21.9 0.0 0.00025 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG12691.1 - 0.0011 18.7 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG12691.1 - 0.0025 18.2 0.0 0.0039 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.27 EGG12693.1 - 1.1e-15 56.7 9.8 9.5e-07 28.4 0.0 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat F-box PF00646.28 EGG12693.1 - 8.4e-08 31.6 2.5 2e-07 30.5 0.2 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EGG12693.1 - 1.9e-05 24.3 0.4 3.5e-05 23.4 0.3 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EGG12693.1 - 0.0013 16.9 0.0 0.0023 16.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EGG12693.1 - 0.0047 17.1 3.3 3.1 8.1 0.0 4.5 5 0 0 5 5 5 1 PQQ-like domain CCDC92 PF14916.1 EGG12693.1 - 0.075 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function eIF3_N PF09440.5 EGG12694.1 - 5e-39 133.5 2.0 9.6e-39 132.5 1.4 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EGG12694.1 - 6.9e-09 35.9 0.0 2.5e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 PCI domain Histone PF00125.19 EGG12695.1 - 4.1e-14 52.4 0.1 5e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGG12695.1 - 3.8e-05 23.7 0.0 5e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EGG12695.1 - 0.00011 22.0 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EGG12695.1 - 0.0013 18.7 0.1 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGG12695.1 - 0.047 12.9 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF455 PF04305.9 EGG12697.1 - 1.4e-88 296.4 0.0 1.4e-88 296.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF455) Rieske PF00355.21 EGG12697.1 - 2.7e-07 30.0 0.0 5.6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Spore_coat_CotO PF14153.1 EGG12697.1 - 0.12 11.7 26.8 0.22 10.9 13.3 2.2 2 0 0 2 2 2 0 Spore coat protein CotO SDA1 PF05285.7 EGG12697.1 - 5.9 6.0 29.1 3.3 6.9 2.2 2.1 2 0 0 2 2 2 0 SDA1 PgaD PF13994.1 EGG12699.1 - 0.041 13.3 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein Gemini_mov PF01708.11 EGG12699.1 - 0.2 11.2 0.3 0.95 9.0 0.0 2.3 2 0 0 2 2 2 0 Geminivirus putative movement protein LEA_2 PF03168.8 EGG12700.1 - 8.1e-06 26.1 0.1 1.9e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Late embryogenesis abundant protein Mito_carr PF00153.22 EGG12701.1 - 2.1e-53 178.0 2.3 1.8e-19 69.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MEKHLA PF08670.6 EGG12701.1 - 0.022 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 MEKHLA domain cwf18 PF08315.7 EGG12702.1 - 2.7e-23 82.8 0.8 3.2e-23 82.5 0.6 1.0 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DEAD PF00270.24 EGG12703.1 - 3e-32 111.4 0.0 1.1e-29 103.1 0.0 2.8 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG12703.1 - 9.2e-22 76.7 0.0 2.7e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGG12703.1 - 2.7e-09 37.1 2.9 1.2e-08 35.0 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FliJ PF02050.11 EGG12707.1 - 0.0017 18.4 1.2 0.0017 18.4 0.8 1.9 2 0 0 2 2 2 1 Flagellar FliJ protein Fib_alpha PF08702.5 EGG12707.1 - 0.023 14.8 2.1 0.023 14.8 1.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 EGG12707.1 - 0.041 13.6 4.5 0.055 13.3 2.4 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.8 EGG12707.1 - 0.27 10.6 3.7 0.33 10.3 1.7 1.8 1 1 0 1 1 1 0 fzo-like conserved region Rootletin PF15035.1 EGG12707.1 - 0.6 10.0 9.0 3.4 7.6 6.4 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Cep57_CLD_2 PF14197.1 EGG12707.1 - 0.94 9.4 8.5 2.4 8.1 0.1 3.3 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 BRE1 PF08647.6 EGG12707.1 - 1.2 9.1 11.5 3.6 7.6 1.5 3.4 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Tropomyosin_1 PF12718.2 EGG12707.1 - 1.4 8.7 12.2 0.21 11.4 3.6 2.3 2 0 0 2 2 2 0 Tropomyosin like DUF948 PF06103.6 EGG12707.1 - 1.7 8.5 5.9 6.4 6.7 3.9 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.6 EGG12707.1 - 2 8.3 6.2 29 4.6 1.0 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 EGG12707.1 - 2.6 7.8 17.2 1.2 8.9 8.6 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 EGG12707.1 - 3.8 5.7 8.6 15 3.8 5.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF342) TPR_MLP1_2 PF07926.7 EGG12707.1 - 4.3 7.0 11.0 14 5.4 7.7 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EGG12707.1 - 4.7 7.0 14.4 23 4.8 6.4 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.15 EGG12707.1 - 5.3 6.8 12.9 11 5.8 6.0 2.7 1 1 0 1 1 1 0 Prefoldin subunit Phage_GP20 PF06810.6 EGG12709.1 - 0.0035 16.8 1.1 0.044 13.2 0.1 2.1 2 0 0 2 2 2 1 Phage minor structural protein GP20 GAS PF13851.1 EGG12709.1 - 0.032 13.4 0.3 0.049 12.8 0.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GluR_Homer-bdg PF10606.4 EGG12709.1 - 0.083 12.8 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Homer-binding domain of metabotropic glutamate receptor ATP-synt_DE PF00401.15 EGG12709.1 - 0.19 11.6 1.9 0.41 10.5 1.3 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain CDP-OH_P_transf PF01066.16 EGG12711.1 - 2.4e-18 66.3 2.3 2.4e-18 66.3 1.6 1.9 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF2721 PF11026.3 EGG12711.1 - 0.013 15.1 0.3 0.11 12.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF3610 PF12272.3 EGG12712.1 - 0.075 12.6 0.2 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) DUF370 PF04025.7 EGG12713.1 - 0.19 11.8 0.8 6.8 6.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF370) Defensin_2 PF01097.13 EGG12718.1 - 8.5e-18 63.7 41.7 0.048 13.3 0.1 15.6 16 0 0 16 16 16 8 Arthropod defensin Mago-bind PF09282.5 EGG12718.1 - 3.6e-08 32.8 5.8 44 3.7 0.0 10.3 13 0 0 13 13 13 1 Mago binding CFEM PF05730.6 EGG12718.1 - 1.3 8.9 191.7 0.32 10.8 3.7 20.2 16 6 0 16 16 16 0 CFEM domain SBF PF01758.11 EGG12719.1 - 0.048 13.0 5.7 0.13 11.6 4.0 1.8 1 1 0 1 1 1 0 Sodium Bile acid symporter family DUF1290 PF06947.7 EGG12719.1 - 0.26 11.1 5.1 0.45 10.4 0.9 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1290) Barwin PF00967.12 EGG12721.1 - 0.0012 18.4 0.2 0.0029 17.2 0.1 1.7 1 0 0 1 1 1 1 Barwin family Mo-co_dimer PF03404.11 EGG12721.1 - 0.024 14.2 0.1 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Mo-co oxidoreductase dimerisation domain BNR PF02012.15 EGG12721.1 - 0.032 14.0 3.3 0.08 12.8 0.5 3.1 3 0 0 3 3 3 0 BNR/Asp-box repeat Pollen_allerg_1 PF01357.16 EGG12721.1 - 0.071 12.9 2.1 0.18 11.6 0.3 2.1 2 0 0 2 2 2 0 Pollen allergen DPBB_1 PF03330.13 EGG12721.1 - 0.084 12.8 0.6 0.33 10.9 0.1 2.2 2 1 0 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel ATP-synt_8 PF00895.15 EGG12721.1 - 0.47 10.6 3.3 0.27 11.4 0.3 2.1 2 0 0 2 2 2 0 ATP synthase protein 8 DUF202 PF02656.10 EGG12722.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF2207 PF09972.4 EGG12722.1 - 0.089 11.3 0.5 0.15 10.6 0.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Shisa PF13908.1 EGG12722.1 - 0.88 9.7 0.0 0.88 9.7 0.0 2.5 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Ilar_coat PF01787.11 EGG12722.1 - 3.3 7.2 7.2 4.2 6.9 4.3 1.7 1 1 0 1 1 1 0 Ilarvirus coat protein PRP21_like_P PF12230.3 EGG12723.1 - 1.9e-44 151.8 29.0 1.9e-44 151.8 20.1 3.6 3 1 0 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EGG12723.1 - 1.8e-27 94.7 0.7 4e-13 48.7 0.1 2.7 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.18 EGG12723.1 - 9.2e-05 21.7 0.1 0.00025 20.3 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family Gly_radical PF01228.16 EGG12723.1 - 0.021 15.1 1.1 0.07 13.4 0.3 2.2 2 0 0 2 2 2 0 Glycine radical Aldo_ket_red PF00248.16 EGG12724.1 - 3.8e-51 173.5 0.0 4.5e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Elongin_A PF06881.6 EGG12725.1 - 8.6e-20 71.1 0.0 2.1e-19 69.9 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A STAT_alpha PF01017.15 EGG12726.1 - 0.0013 18.4 4.1 0.0022 17.7 2.7 1.5 1 1 0 1 1 1 1 STAT protein, all-alpha domain UPF0118 PF01594.11 EGG12726.1 - 0.24 10.3 5.4 0.19 10.6 2.6 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF20 DUF2935 PF11155.3 EGG12726.1 - 0.24 11.4 7.0 1.6 8.8 4.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) BLOC1_2 PF10046.4 EGG12726.1 - 0.35 11.0 6.9 0.77 9.9 4.6 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Herpes_LMP1 PF05297.6 EGG12727.1 - 0.033 13.1 5.6 0.034 13.0 3.9 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Col_cuticle_N PF01484.12 EGG12727.1 - 0.098 12.3 1.0 0.098 12.3 0.7 2.2 1 1 1 2 2 2 0 Nematode cuticle collagen N-terminal domain DUF843 PF05814.6 EGG12727.1 - 0.71 9.7 7.7 0.87 9.4 5.4 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) ALMS_motif PF15309.1 EGG12728.1 - 0.26 11.0 14.5 2.4 8.0 0.2 3.4 3 0 0 3 3 3 0 ALMS motif EMP24_GP25L PF01105.19 EGG12729.1 - 2.7e-47 160.8 0.0 3.1e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PHP PF02811.14 EGG12730.1 - 3.2e-12 46.5 0.1 4.3e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 PHP domain DUF2622 PF11080.3 EGG12730.1 - 0.053 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2622) polyprenyl_synt PF00348.12 EGG12732.1 - 5.3e-37 127.0 0.0 6.5e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SnoaL_2 PF12680.2 EGG12734.1 - 0.048 14.0 0.0 0.067 13.6 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Maf1 PF09174.5 EGG12735.1 - 0.078 12.8 0.2 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Maf1 regulator CMS1 PF14617.1 EGG12736.1 - 4.1e-40 137.4 0.0 2.6e-38 131.5 0.0 2.1 1 1 1 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit GCV_H PF01597.14 EGG12737.1 - 1.8e-40 137.4 0.4 2.1e-40 137.2 0.3 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EGG12737.1 - 0.0014 18.2 0.2 0.0031 17.1 0.1 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.1 EGG12737.1 - 0.013 15.2 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Glyco_hydro_2_C PF02836.12 EGG12738.1 - 0.0026 16.7 0.0 0.0058 15.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EGG12738.1 - 0.018 15.5 0.0 0.065 13.6 0.0 2.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 DUF4158 PF13700.1 EGG12739.1 - 0.0069 15.8 0.4 1.5 8.3 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4158) CDK5_activator PF03261.10 EGG12739.1 - 1 8.6 8.8 1.4 8.1 5.4 1.7 1 1 1 2 2 2 0 Cyclin-dependent kinase 5 activator protein COesterase PF00135.23 EGG12740.1 - 9.5e-76 255.6 0.0 1.2e-75 255.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EGG12740.1 - 4.5e-08 32.5 0.1 7.8e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EGG12740.1 - 6.5e-07 29.1 0.0 5.4e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EGG12740.1 - 0.0039 16.6 0.0 0.0078 15.6 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 EGG12740.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2424 PF10340.4 EGG12740.1 - 0.1 11.1 0.0 0.27 9.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) DNA_repr_REX1B PF14966.1 EGG12741.1 - 1.1e-05 25.7 3.0 0.0012 19.1 0.1 2.6 2 1 1 3 3 3 2 DNA repair REX1-B Corona_RPol_N PF06478.8 EGG12741.1 - 0.085 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Coronavirus RPol N-terminus RVT_3 PF13456.1 EGG12743.1 - 5.4e-09 35.7 0.2 2.1e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase-like EF-hand_2 PF09068.6 EGG12745.1 - 0.06 13.4 0.6 0.17 11.9 0.4 1.8 1 0 0 1 1 1 0 EF hand NPR2 PF06218.6 EGG12747.1 - 1.7e-92 310.4 0.0 6e-78 262.4 0.0 2.1 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 EGG12747.1 - 0.001 17.6 0.0 0.083 11.4 0.0 2.6 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 Epimerase PF01370.16 EGG12748.1 - 5.8e-42 143.7 0.0 7.3e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGG12748.1 - 6.1e-11 41.7 0.1 7.7e-07 28.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EGG12748.1 - 1.4e-10 40.5 0.0 2.4e-10 39.7 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EGG12748.1 - 6.8e-09 34.8 0.0 9.9e-09 34.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGG12748.1 - 0.00054 19.9 0.1 0.2 11.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_10 PF13460.1 EGG12748.1 - 0.00065 19.7 0.0 0.00099 19.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGG12748.1 - 0.0057 15.5 0.0 4.7 6.0 0.0 2.9 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein KR PF08659.5 EGG12748.1 - 0.14 11.7 0.5 5.6 6.5 0.1 2.7 2 1 1 3 3 3 0 KR domain SKI PF01202.17 EGG12749.1 - 0.057 13.2 0.1 0.12 12.2 0.1 1.5 2 0 0 2 2 2 0 Shikimate kinase VirE PF05272.6 EGG12749.1 - 0.086 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Ibs_toxin PF13956.1 EGG12749.1 - 1.9 8.3 5.5 1.2 9.0 2.3 1.8 1 1 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system SRPRB PF09439.5 EGG12751.1 - 1.5e-09 37.3 0.5 3.1e-08 33.0 0.3 2.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EGG12751.1 - 3.9e-05 23.1 0.1 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EGG12751.1 - 0.029 14.2 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGG12751.1 - 0.039 14.0 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EGG12751.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Phytochelatin PF05023.9 EGG12752.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Phytochelatin synthase Pro_dh PF01619.13 EGG12753.1 - 6.4e-36 123.9 0.0 1.1e-34 119.8 0.0 2.1 1 1 0 1 1 1 1 Proline dehydrogenase HBS1_N PF08938.5 EGG12753.1 - 0.31 11.1 1.3 1.7 8.7 0.0 2.8 3 0 0 3 3 3 0 HBS1 N-terminus Adaptin_binding PF10199.4 EGG12754.1 - 9.3 6.5 19.1 23 5.2 12.2 2.4 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 TPT PF03151.11 EGG12755.1 - 2.1e-32 111.8 11.4 2.1e-32 111.8 7.9 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGG12755.1 - 3.4e-10 40.0 24.4 3.1e-05 23.9 3.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EGG12755.1 - 0.017 14.0 22.5 0.18 10.7 15.4 2.5 1 1 1 2 2 2 0 UAA transporter family EmrE PF13536.1 EGG12755.1 - 0.99 9.6 19.2 0.76 9.9 2.8 2.8 2 1 0 2 2 2 0 Multidrug resistance efflux transporter HTH_32 PF13565.1 EGG12757.1 - 0.0025 18.5 0.5 0.015 16.1 0.1 2.4 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.1 EGG12757.1 - 0.037 13.6 0.8 0.58 9.7 0.5 2.3 1 1 0 1 1 1 0 Helix-turn-helix domain mRNA_cap_enzyme PF01331.14 EGG12761.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain zf-C2H2 PF00096.21 EGG12762.1 - 1.5e-05 25.0 10.1 0.0014 18.8 1.8 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGG12762.1 - 0.0012 19.0 3.1 1.2 9.5 0.3 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGG12762.1 - 0.017 15.4 2.7 0.017 15.4 1.8 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Methyltrn_RNA_3 PF02598.12 EGG12763.1 - 7.4e-77 258.5 0.0 3.6e-76 256.2 0.0 1.8 1 1 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 EGG12763.1 - 0.15 11.9 0.0 0.86 9.4 0.0 1.9 2 0 0 2 2 2 0 SpoU rRNA Methylase family EBP PF05241.7 EGG12764.1 - 0.084 11.8 0.2 0.14 11.1 0.2 1.3 1 0 0 1 1 1 0 Emopamil binding protein 2-oxoacid_dh PF00198.18 EGG12765.1 - 1e-50 172.1 0.0 1.5e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGG12765.1 - 1.8e-18 65.9 0.1 4e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EGG12765.1 - 4.8e-14 51.6 0.1 9.2e-14 50.8 0.0 1.4 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EGG12765.1 - 0.00051 19.6 0.1 0.58 9.8 0.0 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.1 EGG12765.1 - 0.014 15.7 0.2 0.047 14.0 0.0 2.0 2 0 0 2 2 2 0 HlyD family secretion protein GCV_H PF01597.14 EGG12765.1 - 0.15 11.7 0.1 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein NAD_binding_5 PF07994.7 EGG12767.1 - 7.1e-105 350.7 0.0 8.9e-105 350.4 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EGG12767.1 - 9.1e-44 147.8 0.1 1.7e-43 146.9 0.1 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Methyltransf_23 PF13489.1 EGG12768.1 - 5.8e-15 55.3 0.0 1.2e-14 54.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG12768.1 - 4.3e-09 36.1 0.0 7.3e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG12768.1 - 6.2e-09 36.2 0.0 1.4e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGG12768.1 - 7.1e-09 36.0 0.0 1.3e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EGG12768.1 - 2.1e-05 23.9 0.0 4.1e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.2 EGG12768.1 - 2.9e-05 24.6 0.0 6.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG12768.1 - 0.00054 20.2 0.0 0.0013 19.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGG12768.1 - 0.0026 16.9 0.0 0.07 12.2 0.0 2.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 EGG12768.1 - 0.0033 16.6 0.0 0.005 16.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_29 PF03141.11 EGG12768.1 - 0.0051 15.1 0.0 0.029 12.7 0.0 1.8 1 1 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.6 EGG12768.1 - 0.055 12.9 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) GHMP_kinases_C PF08544.8 EGG12769.1 - 0.00018 21.6 0.0 0.00055 20.0 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EGG12769.1 - 0.00059 19.8 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain TelA PF05816.6 EGG12769.1 - 0.023 13.4 0.6 0.037 12.7 0.4 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) BEX PF04538.7 EGG12769.1 - 0.039 14.1 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Brain expressed X-linked like family Exo5 PF09810.4 EGG12770.1 - 0.067 12.4 0.5 0.11 11.7 0.4 1.4 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease Pyr_redox_2 PF07992.9 EGG12771.1 - 5e-29 101.6 0.3 7.4e-29 101.0 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EGG12771.1 - 1.1e-13 50.5 0.0 2.7e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 EGG12771.1 - 1.1e-13 51.3 0.9 1.2e-09 38.4 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EGG12771.1 - 4.8e-07 29.4 0.0 1.5e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.1 EGG12771.1 - 1.7e-05 24.9 0.0 0.75 9.8 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EGG12771.1 - 2.2e-05 24.6 0.1 6.1e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 EGG12771.1 - 0.013 14.4 0.0 0.44 9.4 0.0 2.7 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EGG12771.1 - 0.027 13.3 1.3 4.3 6.1 0.0 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase BTB PF00651.26 EGG12776.1 - 8.1e-09 35.4 0.1 0.00031 20.7 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain CMAS PF02353.15 EGG12778.1 - 4.9e-34 117.6 0.1 7.1e-34 117.1 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EGG12778.1 - 2.7e-14 53.3 0.0 4.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGG12778.1 - 9.2e-14 51.4 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGG12778.1 - 9.9e-13 47.9 0.0 1.9e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG12778.1 - 8e-11 42.5 0.0 1.4e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG12778.1 - 1.5e-10 41.4 0.0 2.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG12778.1 - 9.3e-08 31.6 0.0 1.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EGG12778.1 - 0.0002 20.4 0.0 0.00039 19.5 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EGG12778.1 - 0.00037 20.7 0.0 0.00073 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EGG12778.1 - 0.0007 18.6 0.0 0.0015 17.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase TehB PF03848.9 EGG12778.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 EGG12778.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EGG12778.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EGG12778.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain YfkB PF08756.5 EGG12778.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 YfkB-like domain FtsJ PF01728.14 EGG12778.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.10 EGG12778.1 - 0.15 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G LRR_4 PF12799.2 EGG12780.1 - 0.0002 20.8 8.7 0.33 10.6 0.1 5.4 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) F-box PF00646.28 EGG12780.1 - 1.4 8.6 6.2 7.1 6.4 0.1 3.2 3 0 0 3 3 3 0 F-box domain Alpha-amylase PF00128.19 EGG12782.1 - 7.3e-19 68.3 1.3 8.6e-14 51.6 1.2 3.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EGG12782.1 - 1.3e-14 54.3 0.0 2.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EGG12782.1 - 1.6e-05 24.4 0.0 3.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGG12782.1 - 6e-05 23.2 0.0 0.00018 21.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 FSH1 PF03959.8 EGG12783.1 - 1e-10 41.4 0.1 8.1e-05 22.1 0.0 3.1 1 1 2 3 3 3 3 Serine hydrolase (FSH1) zf-CCHC PF00098.18 EGG12784.1 - 7.5e-08 31.9 27.7 0.00037 20.2 0.4 5.3 5 1 0 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.1 EGG12784.1 - 3.4 7.4 30.0 0.24 11.0 1.7 5.3 4 1 2 6 6 6 0 Zinc knuckle Porphobil_deam PF01379.15 EGG12786.1 - 2.9e-76 255.1 0.0 4.3e-76 254.5 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EGG12786.1 - 5.6e-18 64.8 0.0 1.1e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain MCM2_N PF12619.3 EGG12787.1 - 0.93 9.4 5.9 0.44 10.5 1.4 2.1 1 1 1 2 2 2 0 Mini-chromosome maintenance protein 2 Band_7 PF01145.20 EGG12788.1 - 3.3e-24 85.7 2.9 3.3e-24 85.7 2.0 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family Polysacc_deac_1 PF01522.16 EGG12789.1 - 1.1e-27 96.1 0.0 1.8e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_synth_2 PF03142.10 EGG12793.1 - 1.9e-244 811.9 0.0 2.7e-244 811.4 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EGG12793.1 - 3.5e-17 62.7 2.5 1.2e-16 61.0 1.7 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGG12793.1 - 1.8e-15 57.4 0.0 1.5e-13 51.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGG12793.1 - 4.3e-05 22.8 0.1 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.23 EGG12793.1 - 0.0013 18.4 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 EGG12793.1 - 0.0087 15.7 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Abhydrolase_6 PF12697.2 EGG12794.1 - 1.1e-08 35.2 0.0 1.7e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family RRM_1 PF00076.17 EGG12795.1 - 7e-52 172.9 0.1 7.1e-19 67.2 0.0 3.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG12795.1 - 2.5e-37 126.6 0.0 6.2e-13 48.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG12795.1 - 7.2e-26 89.8 1.7 1.4e-08 34.4 0.0 4.3 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGG12795.1 - 0.00018 21.2 0.0 3.3 7.5 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EGG12795.1 - 0.00068 19.5 0.0 1.2 9.1 0.0 2.8 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_2 PF04059.7 EGG12796.1 - 2.6e-33 113.8 0.6 4.4e-33 113.1 0.4 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_6 PF14259.1 EGG12796.1 - 7.6e-05 22.6 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGG12796.1 - 0.1 12.2 0.3 0.33 10.6 0.2 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sigma54_activ_2 PF14532.1 EGG12798.1 - 0.046 13.7 0.6 0.3 11.1 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain Rad60-SLD PF11976.3 EGG12801.1 - 6e-06 25.8 0.0 7.3e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 EGG12802.1 - 8.9e-17 60.5 0.0 7e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGG12802.1 - 1.3e-05 24.4 0.0 0.0048 16.2 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin family UN_NPL4 PF11543.3 EGG12802.1 - 0.0024 18.0 0.0 1.2 9.4 0.0 2.5 3 0 0 3 3 3 2 Nuclear pore localisation protein NPL4 Glyoxal_oxid_N PF07250.6 EGG12803.1 - 4.6e-45 153.5 0.0 1.9e-43 148.3 0.0 2.5 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EGG12803.1 - 2.3e-16 59.6 0.0 4.9e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EGG12803.1 - 0.0049 16.5 0.9 2.8 7.7 0.0 3.9 3 1 1 4 4 4 1 Galactose oxidase, central domain Wzz PF02706.10 EGG12804.1 - 0.099 12.4 0.8 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 Chain length determinant protein TB2_DP1_HVA22 PF03134.14 EGG12805.1 - 6.4e-33 112.3 6.0 8.5e-33 111.9 4.2 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Hum_adeno_E3A PF05393.6 EGG12805.1 - 0.16 11.6 3.5 0.14 11.8 1.2 1.7 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein tRNA-synt_1b PF00579.20 EGG12808.1 - 8.4e-22 77.6 0.0 2.6e-14 53.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Septin PF00735.13 EGG12809.1 - 1.2e-94 316.4 0.0 1.2e-94 316.4 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EGG12809.1 - 4.9e-06 26.4 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGG12809.1 - 3.3e-05 23.1 0.1 6.4e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EGG12809.1 - 0.026 13.6 1.0 0.19 10.7 0.7 2.3 1 1 0 1 1 1 0 AIG1 family AAA_22 PF13401.1 EGG12809.1 - 0.032 14.3 0.0 0.2 11.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EGG12809.1 - 0.032 14.5 0.8 0.075 13.3 0.0 2.0 2 1 0 2 2 2 0 ABC transporter Miro PF08477.8 EGG12809.1 - 0.054 13.9 0.9 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 EGG12809.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EGG12809.1 - 0.12 11.7 0.5 0.43 9.9 0.0 2.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGG12809.1 - 0.45 10.3 7.1 2.3 8.0 0.1 3.2 2 1 1 3 3 3 0 Dynamin family AAA_28 PF13521.1 EGG12809.1 - 0.51 10.2 0.1 0.51 10.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EGG12809.1 - 0.57 11.0 2.5 3 8.6 1.7 2.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGG12809.1 - 1 8.7 4.2 0.18 11.2 0.3 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family SMC_hinge PF06470.8 EGG12811.1 - 3.5e-27 94.7 0.0 9.5e-27 93.3 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.14 EGG12811.1 - 4.6e-26 91.4 22.5 5.2e-26 91.2 15.2 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGG12811.1 - 1.3e-14 55.0 46.3 5e-14 53.1 19.4 4.1 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.1 EGG12811.1 - 7.4e-08 32.7 10.9 5.3e-07 29.8 3.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.1 EGG12811.1 - 0.00095 18.3 0.5 0.00095 18.3 0.4 2.5 2 1 0 2 2 2 1 AAA ATPase domain COG2 PF06148.6 EGG12811.1 - 0.0032 17.3 4.8 0.0032 17.3 3.3 5.4 4 1 1 5 5 5 1 COG (conserved oligomeric Golgi) complex component, COG2 AAA_29 PF13555.1 EGG12811.1 - 0.0043 16.5 0.0 0.0098 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 EGG12811.1 - 0.007 15.9 10.3 0.007 15.9 7.1 4.4 3 1 1 4 4 4 1 IncA protein Rotamase PF00639.16 EGG12811.1 - 4.5 8.0 12.7 0.23 12.2 1.4 3.8 3 0 0 3 3 3 0 PPIC-type PPIASE domain RNA_pol_L_2 PF13656.1 EGG12812.1 - 2.8e-27 93.9 0.0 4.1e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EGG12812.1 - 2.2e-08 33.1 0.0 3.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Spc7 PF08317.6 EGG12813.1 - 0.0057 15.3 7.8 0.0057 15.3 5.4 2.5 1 1 1 2 2 2 1 Spc7 kinetochore protein DUF2450 PF10475.4 EGG12813.1 - 0.01 14.7 2.0 0.01 14.7 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Med9 PF07544.8 EGG12813.1 - 0.21 11.3 20.6 0.11 12.1 3.1 3.6 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Hemerythrin PF01814.18 EGG12813.1 - 0.29 11.2 12.6 0.69 10.0 2.7 3.2 2 1 2 4 4 4 0 Hemerythrin HHE cation binding domain Reo_sigmaC PF04582.7 EGG12813.1 - 0.34 10.0 9.2 1 8.5 0.8 2.8 2 1 0 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EGG12813.1 - 0.35 10.6 35.8 2.5 7.8 2.9 3.5 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Prominin PF05478.6 EGG12813.1 - 0.41 8.1 14.2 0.0047 14.5 2.6 2.0 1 1 1 2 2 2 0 Prominin Phage_GP20 PF06810.6 EGG12813.1 - 0.47 9.8 24.8 0.21 11.0 8.4 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 FliD_N PF02465.13 EGG12813.1 - 0.54 10.6 13.5 0.37 11.1 0.6 3.0 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus ADIP PF11559.3 EGG12813.1 - 0.87 9.4 27.7 2.2 8.1 12.2 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Filament PF00038.16 EGG12813.1 - 1.1 8.6 28.7 0.29 10.5 7.2 2.3 1 1 0 1 1 1 0 Intermediate filament protein Laminin_II PF06009.7 EGG12813.1 - 2.3 7.9 17.3 8.3 6.1 5.7 3.1 1 1 1 2 2 2 0 Laminin Domain II Erythro_esteras PF05139.9 EGG12813.1 - 4.4 6.4 12.5 1 8.5 5.0 2.0 1 1 1 2 2 2 0 Erythromycin esterase CorA PF01544.13 EGG12813.1 - 4.5 6.2 13.8 6.1 5.7 6.0 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein IncA PF04156.9 EGG12813.1 - 5 6.6 32.0 0.27 10.8 2.7 3.0 3 0 0 3 3 3 0 IncA protein DivIC PF04977.10 EGG12813.1 - 5.2 6.6 27.1 13 5.3 0.8 5.0 3 1 2 5 5 5 0 Septum formation initiator Tweety PF04906.8 EGG12813.1 - 9.3 4.5 9.4 1.3 7.3 1.7 2.1 1 1 1 2 2 2 0 Tweety Myb_DNA-bind_3 PF12776.2 EGG12814.1 - 6.5e-23 81.1 3.8 1.2e-22 80.2 0.8 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGG12814.1 - 7.8e-06 25.9 1.0 2.2e-05 24.4 0.2 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.12 EGG12814.1 - 0.082 12.9 0.5 0.19 11.8 0.4 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein SNF2_N PF00176.18 EGG12815.1 - 5.8e-72 242.0 2.5 5.8e-72 242.0 1.7 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EGG12815.1 - 2.4e-20 72.2 2.1 6e-20 70.9 1.1 2.0 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 EGG12815.1 - 6.2e-17 61.2 0.1 2.7e-15 55.9 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EGG12815.1 - 2.5e-13 50.0 0.7 2.5e-13 50.0 0.5 4.9 4 2 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EGG12815.1 - 3.5e-11 42.7 12.6 3.5e-11 42.7 8.7 2.3 2 0 0 2 2 2 1 HSA PPTA PF01239.17 EGG12816.1 - 2.6e-07 29.6 13.1 1.2e-05 24.3 0.1 4.5 5 1 1 6 6 6 2 Protein prenyltransferase alpha subunit repeat MIF4G PF02854.14 EGG12817.1 - 3.8e-27 95.0 0.7 4.3e-26 91.6 0.1 2.3 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EGG12817.1 - 1.3e-25 89.3 0.0 2.5e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 MA3 domain Pkinase PF00069.20 EGG12818.1 - 5.5e-35 120.7 0.0 6.5e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG12818.1 - 1.8e-13 50.1 0.0 2.3e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGG12818.1 - 5.6e-05 22.9 0.0 0.33 10.6 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF2514 PF10721.4 EGG12819.1 - 1.2 8.8 6.5 0.11 12.1 1.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Acetyltransf_3 PF13302.1 EGG12821.1 - 3.1e-18 66.2 0.0 4.5e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGG12821.1 - 2.6e-06 27.1 0.0 4.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EGG12821.1 - 0.032 14.1 0.2 0.22 11.4 0.2 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGG12821.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EGG12821.1 - 0.39 10.6 3.3 0.14 12.0 0.5 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TFIIF_alpha PF05793.7 EGG12824.1 - 0.075 11.3 12.1 0.029 12.7 6.4 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4203 PF13886.1 EGG12826.1 - 1.6e-29 102.8 24.3 2.1e-29 102.4 16.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DKCLD PF08068.7 EGG12827.1 - 1.9e-30 104.5 3.3 3.5e-30 103.7 0.1 2.9 4 0 0 4 4 4 1 DKCLD (NUC011) domain TruB_N PF01509.13 EGG12827.1 - 3.9e-25 88.7 0.4 3.2e-22 79.2 0.2 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EGG12827.1 - 9.6e-22 76.5 1.3 1.6e-21 75.8 0.9 1.4 1 0 0 1 1 1 1 PUA domain SAE2 PF08573.5 EGG12828.1 - 8.1e-12 45.6 8.0 8.1e-12 45.6 5.6 3.7 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF2043 PF09740.4 EGG12829.1 - 0.091 12.8 0.2 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2043) RNase_T PF00929.19 EGG12832.1 - 1.3e-13 51.5 0.0 6.8e-13 49.2 0.0 2.0 1 1 0 1 1 1 1 Exonuclease Nucleoporin_C PF03177.9 EGG12833.1 - 7.1e-56 189.9 10.0 1.6e-55 188.8 6.9 1.5 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EGG12833.1 - 1.3e-13 50.4 1.0 1.7e-13 50.1 0.0 1.6 2 0 0 2 2 2 1 Nup133 N terminal like Gpi1 PF05024.10 EGG12834.1 - 2e-42 144.9 9.4 3e-42 144.4 6.5 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) BDV_P10 PF06515.6 EGG12835.1 - 0.1 12.4 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 Borna disease virus P10 protein Miro PF08477.8 EGG12836.1 - 0.0019 18.7 0.0 0.095 13.2 0.0 2.0 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 EGG12836.1 - 0.0019 17.6 0.0 0.92 8.8 0.0 2.0 1 1 1 2 2 2 2 Ras family polyprenyl_synt PF00348.12 EGG12841.1 - 2.4e-31 108.5 0.0 3.1e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ank_4 PF13637.1 EGG12844.1 - 1.4e-15 57.3 0.5 4.1e-08 33.5 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGG12844.1 - 1.1e-12 48.0 0.0 6.6e-12 45.6 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGG12844.1 - 4.8e-12 45.0 0.1 3.4e-08 32.8 0.1 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EGG12844.1 - 1.2e-09 38.0 0.0 5.3e-07 29.6 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGG12844.1 - 1.4e-07 31.0 0.2 0.00014 21.7 0.1 3.3 3 1 0 3 3 3 1 Ankyrin repeat TAF PF02969.12 EGG12844.1 - 0.049 13.5 0.2 2.4 8.1 0.0 2.6 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) Prefoldin PF02996.12 EGG12845.1 - 1.9e-23 82.4 0.9 2.5e-23 81.9 0.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF1664 PF07889.7 EGG12845.1 - 0.032 14.0 1.8 0.098 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2935 PF11155.3 EGG12845.1 - 0.042 13.9 0.1 0.063 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Syntaxin PF00804.20 EGG12845.1 - 0.11 12.7 2.8 0.35 11.0 0.4 2.1 2 0 0 2 2 2 0 Syntaxin TMF_TATA_bd PF12325.3 EGG12845.1 - 0.12 12.0 5.6 0.14 11.8 0.6 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 EGG12845.1 - 0.31 10.2 5.3 0.48 9.5 0.9 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF998 PF06197.8 EGG12847.1 - 0.12 11.6 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) AF-4 PF05110.8 EGG12849.1 - 0.043 11.7 29.5 0.061 11.1 20.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CAF-1_p150 PF11600.3 EGG12849.1 - 1.3 8.3 23.3 3.4 6.9 16.1 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Corona_nucleoca PF00937.13 EGG12849.1 - 3 6.7 18.3 5.5 5.8 12.7 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SOBP PF15279.1 EGG12849.1 - 3.1 8.0 9.9 5.2 7.3 6.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Pribosyltran PF00156.22 EGG12850.1 - 1.3e-13 50.7 0.1 2.1e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Hat1_N PF10394.4 EGG12851.1 - 1.6e-42 145.2 1.0 3e-42 144.4 0.7 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 EGG12851.1 - 0.00078 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EGG12851.1 - 0.011 15.0 0.2 0.019 14.2 0.2 1.3 1 0 0 1 1 1 0 MOZ/SAS family DDE_Tnp_ISL3 PF01610.12 EGG12851.1 - 0.041 13.4 1.0 0.075 12.6 0.7 1.4 1 0 0 1 1 1 0 Transposase Gemini_mov PF01708.11 EGG12852.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein BatA PF07584.6 EGG12853.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal TMEM154 PF15102.1 EGG12853.1 - 0.33 10.6 4.3 2 8.1 3.0 2.0 1 1 0 1 1 1 0 TMEM154 protein family DUF1691 PF07950.6 EGG12854.1 - 6e-10 39.0 3.4 2.2e-05 24.3 0.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) SH3BGR PF04908.10 EGG12855.1 - 0.084 12.8 0.1 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein SPX PF03105.14 EGG12856.1 - 2e-36 126.2 6.5 3.7e-22 79.4 0.1 2.3 1 1 1 2 2 2 2 SPX domain GDPD PF03009.12 EGG12856.1 - 1.2e-08 34.7 0.0 2.1e-07 30.7 0.0 2.6 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Rhodanese PF00581.15 EGG12860.1 - 8.3e-13 48.6 0.0 1.5e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain ORC6 PF05460.8 EGG12861.1 - 0.017 14.2 3.2 0.02 14.0 2.2 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Rtf2 PF04641.7 EGG12861.1 - 0.06 12.5 7.4 0.072 12.2 5.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger FAM60A PF15396.1 EGG12861.1 - 0.067 12.9 2.2 0.077 12.7 1.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A tRNA-synt_2c PF01411.14 EGG12861.1 - 0.13 10.5 0.8 0.15 10.3 0.6 1.0 1 0 0 1 1 1 0 tRNA synthetases class II (A) Paramyxo_ncap PF00973.14 EGG12861.1 - 0.17 10.5 2.6 0.19 10.3 1.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein XAP5 PF04921.9 EGG12861.1 - 2.8 7.4 8.7 3.4 7.1 6.0 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator TFIIA PF03153.8 EGG12862.1 - 0.0021 18.0 29.0 0.004 17.1 20.1 1.5 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit UbiA PF01040.13 EGG12863.1 - 1.4e-34 119.5 18.6 1.7e-34 119.2 12.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ost4 PF10215.4 EGG12863.1 - 0.017 14.5 0.4 0.059 12.8 0.3 1.9 1 0 0 1 1 1 0 Oligosaccaryltransferase SKG6 PF08693.5 EGG12864.1 - 0.055 12.8 0.0 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EIID-AGA PF03613.9 EGG12864.1 - 0.22 10.4 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component Ctr PF04145.10 EGG12864.1 - 5.5 7.0 0.0 5.5 7.0 0.0 3.0 2 1 0 2 2 2 0 Ctr copper transporter family Sulf_transp PF04143.9 EGG12865.1 - 3.7e-14 52.4 25.2 1.1e-08 34.9 6.5 3.8 5 0 0 5 5 5 2 Sulphur transport DUF4341 PF14241.1 EGG12865.1 - 5.4e-07 29.2 4.8 5.4e-07 29.2 3.3 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4341) p450 PF00067.17 EGG12867.1 - 1.6e-50 171.9 0.0 2.2e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ureidogly_hydro PF04115.7 EGG12868.1 - 2.4e-38 131.0 0.0 3e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Allantoicase PF03561.10 EGG12868.1 - 0.0072 15.8 0.2 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 Allantoicase repeat Peptidase_C12 PF01088.16 EGG12869.1 - 2.2e-60 203.5 0.0 2.5e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SKN1 PF03935.10 EGG12870.1 - 8.2e-202 670.8 2.6 9.1e-202 670.6 1.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_3 PF00933.16 EGG12872.1 - 2.7e-79 266.2 0.0 4e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGG12872.1 - 6.7e-55 186.0 0.3 1.3e-54 185.1 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGG12872.1 - 3.8e-22 78.0 0.6 7.8e-22 77.0 0.4 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3664 PF12406.3 EGG12875.1 - 0.56 10.8 4.7 0.83 10.2 3.2 1.3 1 0 0 1 1 1 0 Surface protein tRNA-synt_1c PF00749.16 EGG12876.1 - 6.8e-103 343.6 0.1 8.9e-103 343.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGG12876.1 - 4.6e-34 117.5 0.1 9.9e-34 116.5 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EGG12876.1 - 8.8e-06 26.1 0.1 3.5e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGG12876.1 - 0.0047 16.7 0.1 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGG12876.1 - 0.0057 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4164 PF13747.1 EGG12877.1 - 0.0009 19.3 4.8 0.0017 18.4 3.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) Sipho_Gp157 PF05565.6 EGG12877.1 - 0.0025 17.4 2.7 0.0045 16.5 1.9 1.4 1 0 0 1 1 1 1 Siphovirus Gp157 Myosin_HC-like PF07058.6 EGG12877.1 - 0.0076 15.3 3.3 0.02 13.9 2.2 1.6 1 1 0 1 1 1 1 Myosin II heavy chain-like DDE_Tnp_IS240 PF13610.1 EGG12877.1 - 0.0093 15.9 0.4 0.015 15.2 0.3 1.2 1 0 0 1 1 1 1 DDE domain DUF4200 PF13863.1 EGG12877.1 - 0.011 15.7 7.0 0.018 15.0 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.7 EGG12877.1 - 0.025 14.3 0.4 0.04 13.7 0.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 EGG12877.1 - 0.03 13.8 6.3 0.044 13.2 4.4 1.2 1 0 0 1 1 1 0 Intermediate filament protein YjcZ PF13990.1 EGG12877.1 - 0.03 13.4 1.1 0.044 12.9 0.7 1.2 1 0 0 1 1 1 0 YjcZ-like protein CK2S PF15011.1 EGG12877.1 - 0.042 13.6 1.2 0.087 12.6 0.7 1.6 1 1 0 1 1 1 0 Casein Kinase 2 substrate DUF883 PF05957.8 EGG12877.1 - 0.089 13.2 1.4 0.17 12.3 1.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.6 EGG12877.1 - 0.16 9.4 1.6 0.21 9.0 1.1 1.1 1 0 0 1 1 1 0 Prominin Spectrin PF00435.16 EGG12877.1 - 0.29 11.4 4.0 0.54 10.5 2.1 1.9 1 1 1 2 2 2 0 Spectrin repeat IncA PF04156.9 EGG12877.1 - 2.6 7.5 8.4 4.6 6.7 5.8 1.3 1 0 0 1 1 1 0 IncA protein Med4 PF10018.4 EGG12878.1 - 0.019 14.3 0.3 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 SlyX PF04102.7 EGG12879.1 - 0.089 13.1 0.2 0.3 11.4 0.1 1.9 1 0 0 1 1 1 0 SlyX ADIP PF11559.3 EGG12879.1 - 0.3 10.9 4.7 0.13 12.1 0.2 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 EGG12879.1 - 0.35 10.6 1.5 0.56 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) XPA_N PF01286.13 EGG12880.1 - 0.58 9.8 4.9 1.3 8.7 3.4 1.6 1 0 0 1 1 1 0 XPA protein N-terminal TRAPP PF04051.11 EGG12881.1 - 4.9e-28 97.5 0.0 6e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component tRNA-synt_2b PF00587.20 EGG12882.1 - 1.9e-19 69.8 0.0 6.6e-19 68.1 0.0 1.9 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_hydro_28 PF00295.12 EGG12884.1 - 4.5e-20 71.8 4.6 4.5e-20 71.8 3.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 EGG12884.1 - 7.3e-05 22.9 8.3 0.00026 21.1 0.1 2.8 2 1 0 3 3 3 2 Pectate lyase superfamily protein Pkinase PF00069.20 EGG12885.1 - 3.9e-43 147.4 0.4 6.6e-24 84.4 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGG12885.1 - 4.3e-13 48.9 0.3 5.3e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGG12885.1 - 0.34 9.6 0.0 0.47 9.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF604 PF04646.7 EGG12888.1 - 1.2e-13 50.8 0.5 2.7e-13 49.7 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EGG12888.1 - 2.7e-08 33.3 0.0 5.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Fringe-like Tyrosinase PF00264.15 EGG12889.1 - 2.1e-12 47.6 1.5 2.1e-12 47.6 1.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3605 PF12239.3 EGG12890.1 - 1.2e-16 60.9 7.2 3.5e-14 52.9 1.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) Tox-ART-HYD1 PF15633.1 EGG12890.1 - 0.019 15.7 0.2 0.52 11.1 0.0 2.3 2 0 0 2 2 2 0 HYD1 signature containing ADP-ribosyltransferase SnoaL_2 PF12680.2 EGG12891.1 - 8.4e-06 26.1 0.0 1.2e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EGG12891.1 - 0.06 13.5 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Spc24 PF08286.6 EGG12892.1 - 2.8e-05 23.7 3.0 0.00055 19.6 0.0 2.3 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Spc7 PF08317.6 EGG12892.1 - 0.0029 16.3 4.3 0.004 15.8 3.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein APG6 PF04111.7 EGG12892.1 - 0.0056 15.7 6.8 0.0075 15.3 4.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF4618 PF15397.1 EGG12892.1 - 0.0086 15.4 2.0 0.012 14.9 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) MscS_porin PF12795.2 EGG12892.1 - 0.011 15.0 7.8 0.016 14.5 5.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF2968 PF11180.3 EGG12892.1 - 0.012 15.0 6.4 0.016 14.6 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF3340 PF11818.3 EGG12892.1 - 0.018 14.9 5.0 0.026 14.4 3.4 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF869 PF05911.6 EGG12892.1 - 0.033 12.4 6.9 0.041 12.1 4.8 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Fib_alpha PF08702.5 EGG12892.1 - 0.04 14.0 4.8 0.061 13.4 3.3 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4559 PF15112.1 EGG12892.1 - 0.078 12.1 3.2 0.095 11.8 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF3782 PF12644.2 EGG12892.1 - 0.23 11.2 1.9 0.54 10.0 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) YlqD PF11068.3 EGG12892.1 - 0.39 10.7 5.9 0.67 10.0 1.7 2.2 2 0 0 2 2 2 0 YlqD protein Atg14 PF10186.4 EGG12892.1 - 0.42 9.5 6.7 0.59 9.0 4.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 EGG12892.1 - 0.67 9.8 8.2 1.1 9.1 5.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EGG12892.1 - 1.2 9.0 14.0 2.2 8.2 9.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 EGG12892.1 - 1.4 8.6 12.4 5.5 6.7 7.5 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 EGG12892.1 - 3.9 7.0 7.3 7.9 6.0 0.2 2.4 1 1 1 2 2 2 0 Septum formation initiator Tim17 PF02466.14 EGG12893.1 - 3.2e-36 124.1 8.0 3.8e-36 123.9 5.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3600 PF12207.3 EGG12894.1 - 0.15 11.6 0.0 2.2 7.7 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3600) eIF_4EBP PF05456.6 EGG12898.1 - 1.9 8.2 4.2 0.49 10.1 0.7 1.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Arrestin_N PF00339.24 EGG12899.1 - 1.5e-05 24.8 0.4 4.2e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Ins_P5_2-kin PF06090.7 EGG12902.1 - 3.8e-49 167.4 0.0 5.8e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase FAR1 PF03101.10 EGG12904.1 - 0.00011 22.5 0.0 0.00021 21.7 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EGG12904.1 - 0.096 12.8 0.1 0.32 11.2 0.0 1.8 1 1 0 1 1 1 0 Transcription factor AFT DUF4208 PF13907.1 EGG12904.1 - 0.12 12.5 0.2 0.32 11.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) BC10 PF06726.7 EGG12905.1 - 3.8e-08 33.2 11.1 3.8e-08 33.2 7.7 2.2 2 0 0 2 2 2 1 Bladder cancer-related protein BC10 GNAT_acetyltr_2 PF13718.1 EGG12906.1 - 0.085 12.1 0.0 0.25 10.6 0.0 1.7 1 1 0 1 1 1 0 GNAT acetyltransferase 2 RFC1 PF08519.7 EGG12907.1 - 4.1e-48 163.0 0.0 3.4e-47 160.0 0.0 2.6 3 0 0 3 3 3 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EGG12907.1 - 6e-15 55.1 0.0 2.5e-14 53.1 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EGG12907.1 - 3.8e-10 40.0 0.4 1.6e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EGG12907.1 - 3.9e-08 32.4 0.2 2.6e-07 29.7 0.1 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EGG12907.1 - 1.5e-05 25.7 1.8 1.7e-05 25.6 0.1 2.0 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EGG12907.1 - 2.3e-05 24.5 0.1 0.00013 22.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGG12907.1 - 6.5e-05 23.2 1.3 0.00028 21.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EGG12907.1 - 0.0012 18.7 0.0 0.0042 16.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EGG12907.1 - 0.0013 18.7 0.0 0.016 15.2 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EGG12907.1 - 0.0044 16.7 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain PTCB-BRCT PF12738.2 EGG12907.1 - 0.0076 16.0 0.1 0.023 14.5 0.1 1.8 1 0 0 1 1 1 1 twin BRCT domain AAA_28 PF13521.1 EGG12907.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EGG12907.1 - 0.016 14.2 0.0 0.041 12.9 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 EGG12907.1 - 0.031 14.0 0.5 0.11 12.2 0.3 2.0 1 1 1 2 2 2 0 NTPase AAA_5 PF07728.9 EGG12907.1 - 0.032 13.9 0.0 0.11 12.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PBP1_TM PF14812.1 EGG12907.1 - 0.05 13.9 23.6 0.038 14.2 11.1 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NACHT PF05729.7 EGG12907.1 - 0.067 12.8 0.0 5.4 6.6 0.0 2.7 2 0 0 2 2 2 0 NACHT domain DUF4611 PF15387.1 EGG12907.1 - 0.077 13.1 18.1 0.015 15.4 7.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AAA_33 PF13671.1 EGG12907.1 - 0.094 12.5 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Nucleoplasmin PF03066.10 EGG12907.1 - 4.7 6.7 14.9 8.7 5.8 5.5 2.6 2 0 0 2 2 2 0 Nucleoplasmin Pkinase PF00069.20 EGG12910.1 - 1.5e-48 165.2 0.0 2.1e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EGG12910.1 - 5.8e-37 126.4 1.9 3e-36 124.1 1.3 2.1 1 1 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EGG12910.1 - 1e-24 87.0 0.0 2.1e-24 86.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Chlamy_scaf PF09675.5 EGG12910.1 - 0.04 13.9 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) Kdo PF06293.9 EGG12910.1 - 0.062 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4423 PF14394.1 EGG12910.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Actin PF00022.14 EGG12911.1 - 8.8e-44 149.4 0.0 3.1e-23 81.8 0.0 2.2 2 0 0 2 2 2 2 Actin Glyco_hydro_28 PF00295.12 EGG12912.1 - 5.5e-25 88.0 0.0 5.7e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 EGG12912.1 - 1.4e-06 28.6 2.9 1.1e-05 25.6 2.0 2.3 1 1 0 1 1 1 1 Pectate lyase superfamily protein Hydrolase_6 PF13344.1 EGG12913.1 - 2.5e-22 78.6 0.0 6.6e-22 77.3 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGG12913.1 - 1.4e-20 72.7 0.0 3.2e-20 71.6 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EGG12913.1 - 0.00072 20.0 0.0 0.021 15.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGG12913.1 - 0.0036 17.5 0.0 0.021 15.0 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase AATF-Che1 PF13339.1 EGG12914.1 - 8.2 6.5 8.4 4 7.6 2.6 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Plasmid_stabil PF05016.9 EGG12916.1 - 0.83 10.0 4.1 7.4 7.0 0.2 3.1 2 1 1 3 3 3 0 Plasmid stabilisation system protein HbrB PF08539.6 EGG12917.1 - 2.4e-15 56.7 0.2 8.9e-15 54.8 0.1 1.9 1 1 0 1 1 1 1 HbrB-like NapD PF03927.8 EGG12917.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 NapD protein Spore_III_AF PF09581.5 EGG12918.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Lumazine_bd PF12870.2 EGG12918.1 - 0.043 13.8 0.1 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Lumazine-binding domain Protoglobin PF11563.3 EGG12918.1 - 0.044 13.4 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Protoglobin GET2 PF08690.5 EGG12920.1 - 6.8e-05 22.2 0.1 0.00014 21.2 0.1 1.5 1 1 0 1 1 1 1 GET complex subunit GET2 CAML PF14963.1 EGG12920.1 - 0.016 14.6 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF3021 PF11457.3 EGG12920.1 - 0.34 10.8 4.1 0.27 11.1 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) WD40 PF00400.27 EGG12921.1 - 1.5e-51 170.5 7.6 1.8e-10 40.2 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EGG12921.1 - 2.6e-11 42.3 4.4 0.0025 16.0 0.0 4.7 3 2 1 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGG12921.1 - 0.0025 16.6 1.1 0.041 12.6 0.0 2.7 2 2 0 2 2 2 1 Nup133 N terminal like Bromodomain PF00439.20 EGG12925.1 - 1.3e-23 82.7 0.1 1.5e-23 82.5 0.1 1.1 1 0 0 1 1 1 1 Bromodomain Bromodomain PF00439.20 EGG12926.1 - 4.2e-20 71.4 0.0 9.1e-20 70.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Lzipper-MIP1 PF14389.1 EGG12926.1 - 0.01 15.9 0.4 0.022 14.8 0.2 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Toprim_3 PF13362.1 EGG12926.1 - 0.14 12.4 0.9 0.81 9.9 0.0 2.5 2 1 1 3 3 3 0 Toprim domain DUF2360 PF10152.4 EGG12927.1 - 7.4 6.8 14.2 0.32 11.2 2.9 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Glyco_hydro_3 PF00933.16 EGG12928.1 - 2.1e-79 266.6 0.0 3e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGG12928.1 - 5e-51 173.4 0.1 7.8e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGG12928.1 - 1.6e-21 75.9 0.1 3.3e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain HMG_box PF00505.14 EGG12929.1 - 2.5e-19 69.3 0.2 5e-19 68.3 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGG12929.1 - 1.7e-14 53.9 0.0 3.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain SNF2_N PF00176.18 EGG12934.1 - 8.3e-14 51.0 0.5 4.5e-13 48.6 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGG12934.1 - 4e-11 42.6 0.1 1.3e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MAS20 PF02064.10 EGG12935.1 - 0.038 13.8 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor CCDC84 PF14968.1 EGG12935.1 - 0.063 12.7 0.1 0.074 12.5 0.1 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 Alpha_adaptin_C PF02296.11 EGG12935.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.5 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain WD40 PF00400.27 EGG12939.1 - 5.9e-33 111.5 7.9 2.1e-11 43.2 0.2 7.6 7 1 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EGG12939.1 - 5.6e-05 23.2 0.2 0.99 9.7 0.0 4.3 3 1 0 3 3 3 2 PQQ-like domain BBS2_Mid PF14783.1 EGG12939.1 - 0.026 14.2 0.0 13 5.5 0.0 3.6 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region CBM_3 PF00942.13 EGG12940.1 - 0.25 11.3 1.8 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 Cellulose binding domain Arm PF00514.18 EGG12941.1 - 1.9e-68 224.1 26.3 9.1e-12 44.3 0.0 11.8 12 0 0 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGG12941.1 - 1.7e-25 89.1 8.3 1.9e-06 28.0 0.1 6.9 3 1 5 8 8 8 7 HEAT repeats HEAT PF02985.17 EGG12941.1 - 4.9e-21 72.8 10.1 0.095 12.8 0.0 9.8 9 0 0 9 9 9 6 HEAT repeat HEAT_EZ PF13513.1 EGG12941.1 - 1.1e-14 54.3 13.4 0.018 15.5 0.1 8.5 7 2 2 9 9 9 5 HEAT-like repeat Adaptin_N PF01602.15 EGG12941.1 - 2e-11 42.9 5.8 5.3e-09 34.9 0.2 2.3 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 EGG12941.1 - 2.9e-10 39.6 8.9 4.2e-08 32.6 1.1 3.6 1 1 3 4 4 4 3 Armadillo-like V-ATPase_H_N PF03224.9 EGG12941.1 - 2.5e-08 33.4 0.8 0.0022 17.1 0.2 4.1 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.7 EGG12941.1 - 2.6e-07 29.0 0.1 3.7e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Cnd1 PF12717.2 EGG12941.1 - 9.5e-05 22.3 1.1 0.78 9.5 0.0 3.6 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.3 EGG12941.1 - 0.0019 18.1 1.6 4.1 7.3 0.1 4.4 2 1 3 5 5 5 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 EGG12941.1 - 0.0041 17.4 0.2 6.7 7.1 0.0 3.7 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region DUF908 PF06012.7 EGG12941.1 - 0.0096 15.2 4.4 2.2 7.4 0.1 3.8 1 1 3 4 4 4 1 Domain of Unknown Function (DUF908) HEAT_PBS PF03130.11 EGG12941.1 - 0.042 14.3 8.2 1.1e+02 3.6 0.0 7.0 8 0 0 8 8 6 0 PBS lyase HEAT-like repeat DUF1368 PF07112.6 EGG12941.1 - 0.19 10.2 0.0 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) Atx10homo_assoc PF09759.4 EGG12941.1 - 0.36 10.5 3.6 0.48 10.1 0.1 2.9 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain zf-C2H2 PF00096.21 EGG12942.1 - 0.00044 20.4 0.8 0.00044 20.4 0.6 1.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.2 EGG12942.1 - 0.0068 16.5 3.1 0.019 15.1 0.2 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EGG12942.1 - 0.019 15.3 2.5 0.038 14.3 1.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 EGG12942.1 - 0.021 14.3 1.5 0.066 12.7 1.0 2.0 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger zf-Di19 PF05605.7 EGG12942.1 - 0.15 12.1 0.5 0.15 12.1 0.3 1.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Cyclin PF08613.6 EGG12943.1 - 7e-13 49.2 1.1 1.3e-12 48.4 0.0 2.0 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EGG12943.1 - 1.6e-05 24.4 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Zn_clus PF00172.13 EGG12945.1 - 0.00015 21.5 12.2 0.0054 16.6 3.1 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Transket_pyr PF02779.19 EGG12946.1 - 8.3e-37 126.3 0.0 1.2e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGG12946.1 - 2.5e-32 111.4 0.1 2.6e-31 108.1 0.0 2.4 2 1 0 2 2 2 1 Transketolase, C-terminal domain DUF4116 PF13475.1 EGG12946.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) tRNA_int_endo PF01974.12 EGG12947.1 - 3.5e-14 52.3 0.0 6.7e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain NCKAP5 PF15246.1 EGG12947.1 - 1.6 8.0 8.4 2.1 7.6 5.8 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Tfb2 PF03849.9 EGG12949.1 - 6.1e-120 400.2 4.5 7.2e-120 399.9 3.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EGG12949.1 - 0.0012 18.5 0.0 0.0032 17.2 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Orn_Arg_deC_N PF02784.11 EGG12949.1 - 0.087 11.9 0.0 0.24 10.5 0.0 1.7 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Syja_N PF02383.13 EGG12950.1 - 3.2e-81 272.5 0.2 6.9e-81 271.4 0.0 1.7 2 0 0 2 2 2 1 SacI homology domain hSac2 PF12456.3 EGG12950.1 - 4.9e-27 93.6 0.0 1.2e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Inositol phosphatase RNA_pol_N PF01194.12 EGG12952.1 - 8.5e-31 105.7 0.4 1.1e-30 105.4 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit CFEM PF05730.6 EGG12953.1 - 7.1e-14 51.3 9.3 1e-13 50.8 6.5 1.2 1 0 0 1 1 1 1 CFEM domain Alk_phosphatase PF00245.15 EGG12953.1 - 0.24 10.0 0.7 0.25 9.9 0.5 1.1 1 0 0 1 1 1 0 Alkaline phosphatase Swi3 PF07962.7 EGG12954.1 - 5.9e-23 80.2 0.1 1.1e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Cwf_Cwc_15 PF04889.7 EGG12954.1 - 0.017 14.8 1.3 0.045 13.4 0.9 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DPBB_1 PF03330.13 EGG12955.1 - 2.2e-09 37.1 0.6 8.6e-09 35.2 0.0 2.3 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGG12955.1 - 0.0013 18.4 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Barwin family DnaJ PF00226.26 EGG12956.1 - 3.9e-27 93.7 0.5 6.4e-27 93.0 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGG12956.1 - 4.7e-17 61.6 0.0 1.5e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGG12956.1 - 4.5e-15 55.4 15.3 8.4e-15 54.5 10.6 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGG12956.1 - 0.051 13.2 5.2 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 EGG12956.1 - 1.8 8.9 8.7 1 9.6 2.4 2.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF3317 PF11779.3 EGG12957.1 - 1.9e-10 39.9 5.2 2.4e-10 39.6 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) PIRT PF15099.1 EGG12958.1 - 0.13 11.5 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF1776 PF08643.5 EGG12959.1 - 5.1e-07 29.1 0.6 9.3e-07 28.2 0.0 1.8 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Ribosomal_S4 PF00163.14 EGG12962.1 - 5.2e-16 58.7 0.9 8.9e-16 58.0 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EGG12962.1 - 5.9e-11 41.6 0.0 1.4e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain NRDE PF05742.7 EGG12962.1 - 0.088 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 NRDE protein Chorismate_bind PF00425.13 EGG12963.1 - 1.1e-85 287.1 0.0 1.4e-85 286.7 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EGG12963.1 - 3.3e-22 78.9 0.0 3.9e-21 75.5 0.0 2.7 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region TPR_11 PF13414.1 EGG12965.1 - 2.5e-24 84.7 0.3 5.9e-11 41.8 0.1 4.5 4 0 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 EGG12965.1 - 1.5e-22 77.5 0.2 0.0002 21.0 0.9 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 EGG12965.1 - 4.4e-20 70.3 2.6 0.00021 20.7 1.4 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGG12965.1 - 2.1e-14 52.1 1.0 0.18 11.6 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGG12965.1 - 6.9e-12 45.1 0.3 0.0029 17.5 0.0 5.0 5 1 0 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 EGG12965.1 - 8.4e-10 38.6 2.5 5.7e-06 26.3 0.1 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EGG12965.1 - 6.6e-08 32.7 0.0 0.042 14.1 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGG12965.1 - 6.4e-07 29.8 0.0 0.48 11.1 0.0 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGG12965.1 - 7.2e-07 28.9 0.2 0.57 10.5 0.0 6.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGG12965.1 - 1.3e-05 25.3 0.0 5.7 7.8 0.0 5.3 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGG12965.1 - 3.2e-05 24.0 0.6 7.5 7.2 0.0 5.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGG12965.1 - 8e-05 22.1 0.0 5.3 7.0 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat p450 PF00067.17 EGG12967.1 - 8.9e-69 232.1 0.0 1.2e-68 231.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGG12968.1 - 1.8e-53 181.7 0.0 2.6e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M26_C PF07580.9 EGG12968.1 - 0.012 13.9 0.0 0.017 13.4 0.0 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region AMP-binding PF00501.23 EGG12969.1 - 2.3e-54 184.4 0.0 3.8e-49 167.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Alpha_kinase PF02816.13 EGG12971.1 - 1.7e-11 44.1 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family ATP12 PF07542.6 EGG12972.1 - 3.3e-41 140.0 0.1 5.6e-41 139.3 0.1 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein LRR_8 PF13855.1 EGG12973.1 - 0.052 13.3 0.1 0.15 11.8 0.1 1.7 2 0 0 2 2 2 0 Leucine rich repeat Galactosyl_T PF01762.16 EGG12974.1 - 0.0048 16.5 0.3 5.4 6.5 0.0 3.1 2 1 1 3 3 3 2 Galactosyltransferase V-SNARE PF05008.10 EGG12976.1 - 0.035 14.2 1.2 0.07 13.3 0.8 1.5 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus YukC PF10140.4 EGG12976.1 - 0.05 12.1 1.2 0.074 11.6 0.9 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC RHH_4 PF13467.1 EGG12977.1 - 0.13 12.1 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribbon-helix-helix domain AMP-binding PF00501.23 EGG12978.1 - 1.2e-76 257.8 0.0 1.5e-76 257.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGG12978.1 - 2.6e-17 63.5 0.1 8.1e-17 61.9 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EGG12978.1 - 0.058 11.9 0.0 0.33 9.4 0.1 1.9 2 0 0 2 2 2 0 GH3 auxin-responsive promoter DUF2629 PF10945.3 EGG12979.1 - 0.014 14.6 0.1 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2629) Lum_binding PF00677.12 EGG12981.1 - 1.9e-35 120.6 1.5 2.2e-22 78.7 0.1 2.8 2 1 0 2 2 2 2 Lumazine binding domain CDC45 PF02724.9 EGG12982.1 - 0.1 10.6 9.1 0.041 11.9 4.4 1.7 2 0 0 2 2 2 0 CDC45-like protein TATR PF03430.8 EGG12982.1 - 0.77 8.3 8.5 1.2 7.7 5.9 1.4 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Hid1 PF12722.2 EGG12982.1 - 8.8 3.8 8.4 11 3.5 5.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF261 PF03196.8 EGG12983.1 - 0.048 13.6 0.3 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF261 Leu_zip PF15294.1 EGG12983.1 - 0.059 12.4 0.3 0.08 12.0 0.2 1.3 1 0 0 1 1 1 0 Leucine zipper FAR1 PF03101.10 EGG12984.1 - 8.9e-05 22.9 1.5 0.00013 22.3 1.0 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EGG12984.1 - 0.008 16.3 1.7 0.013 15.6 1.1 1.4 1 1 0 1 1 1 1 Transcription factor AFT Allexi_40kDa PF05549.6 EGG12986.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein DBP10CT PF08147.7 EGG12988.1 - 0.0013 18.4 0.5 0.0088 15.8 0.0 2.6 3 1 0 3 3 3 1 DBP10CT (NUC160) domain Syntaxin PF00804.20 EGG12988.1 - 0.0024 17.9 0.1 0.0036 17.4 0.1 1.3 1 0 0 1 1 1 1 Syntaxin F-box-like PF12937.2 EGG12989.1 - 2.5e-05 23.8 0.0 7.3e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 F-box-like Ndc1_Nup PF09531.5 EGG12989.1 - 0.18 10.1 0.6 0.21 9.9 0.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2935 PF11155.3 EGG12990.1 - 0.1 12.7 2.0 0.36 10.9 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Alpha_kinase PF02816.13 EGG12991.1 - 4.7e-26 91.6 2.0 6.5e-26 91.1 1.4 1.2 1 0 0 1 1 1 1 Alpha-kinase family SOBP PF15279.1 EGG12992.1 - 0.33 11.3 16.1 0.068 13.5 8.1 1.9 2 0 0 2 2 2 0 Sine oculis-binding protein CDC45 PF02724.9 EGG12992.1 - 3.4 5.6 26.6 5.1 5.0 18.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 EGG12992.1 - 6.5 4.9 20.0 9.1 4.4 13.8 1.3 1 0 0 1 1 1 0 Transmembrane protein RP-C_C PF11800.3 EGG12993.1 - 0.59 9.7 2.3 0.51 10.0 0.2 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region Lipoprotein_6 PF01441.14 EGG12993.1 - 1.8 8.4 6.8 0.099 12.4 0.9 1.7 2 0 0 2 2 2 0 Lipoprotein SGT1 PF07093.6 EGG12994.1 - 1.4e-102 344.0 61.8 4.3e-95 319.3 23.0 2.1 1 1 1 2 2 2 2 SGT1 protein YjeF_N PF03853.10 EGG12996.1 - 9.9e-07 28.5 0.2 2.4e-05 23.9 0.2 2.2 1 1 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EGG12996.1 - 4.1e-06 27.2 0.1 1.2e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 EGG12996.1 - 0.018 14.9 0.1 0.056 13.3 0.1 1.9 1 1 0 1 1 1 0 Ataxin 2 SM domain Cytochrom_B_N PF00033.14 EGG12997.1 - 0.0037 16.6 0.0 0.034 13.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 EGG12997.1 - 0.0089 15.4 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 Pex14_N PF04695.8 EGG12997.1 - 0.0095 15.9 0.5 0.0095 15.9 0.3 2.5 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM154 PF15102.1 EGG12997.1 - 0.4 10.3 4.7 0.99 9.1 0.0 2.4 2 1 0 2 2 2 0 TMEM154 protein family ODV-E18 PF10717.4 EGG12997.1 - 1 8.8 0.0 1 8.8 0.0 3.4 3 1 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Shisa PF13908.1 EGG12997.1 - 1.8 8.6 8.7 15 5.7 1.2 3.0 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator adh_short PF00106.20 EGG12998.1 - 3.1e-16 59.7 0.0 4.8e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGG12998.1 - 6.8e-07 29.1 0.2 1.7e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 KR domain Melibiase PF02065.13 EGG12999.1 - 5.7e-07 28.5 0.2 1.1e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 Melibiase Pex2_Pex12 PF04757.9 EGG13001.1 - 1.1e-46 159.0 7.1 1.4e-46 158.7 4.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EGG13001.1 - 7.9e-06 25.7 5.1 1.5e-05 24.9 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG13001.1 - 0.00015 21.3 3.3 0.00032 20.2 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGG13001.1 - 0.077 12.8 5.7 0.2 11.5 3.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EGG13001.1 - 0.15 11.7 2.7 0.27 10.9 1.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGG13001.1 - 1 9.2 5.6 2.8 7.8 3.9 1.8 1 0 0 1 1 1 0 Ring finger domain Agro_virD5 PF04730.7 EGG13002.1 - 6.5 4.6 10.8 8.3 4.3 7.5 1.0 1 0 0 1 1 1 0 Agrobacterium VirD5 protein Septin PF00735.13 EGG13003.1 - 3.7e-105 350.9 0.1 6.7e-105 350.1 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EGG13003.1 - 0.0021 17.9 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EGG13003.1 - 0.018 15.8 1.0 0.081 13.7 0.7 2.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGG13003.1 - 0.023 14.8 0.2 0.23 11.5 0.0 2.4 2 2 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGG13003.1 - 0.029 13.5 0.1 0.069 12.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EGG13003.1 - 0.057 12.8 0.1 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EGG13003.1 - 0.074 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EGG13003.1 - 0.11 13.0 0.2 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Gelsolin PF00626.17 EGG13004.1 - 1.8e-09 37.1 0.1 5e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 Gelsolin repeat PS_Dcarbxylase PF02666.10 EGG13005.1 - 2.8e-68 229.2 0.0 5.9e-67 224.8 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Atg14 PF10186.4 EGG13006.1 - 6.9e-12 44.9 6.9 6.9e-12 44.9 4.8 2.0 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 DoxD PF04173.8 EGG13006.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 TQO small subunit DoxD Y_phosphatase PF00102.22 EGG13007.1 - 8.4e-49 166.0 0.0 9.8e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EGG13007.1 - 3.3e-05 23.4 0.0 4.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EGG13007.1 - 0.0004 20.6 0.0 0.00053 20.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EGG13007.1 - 0.0035 17.3 0.0 0.048 13.6 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate Med2 PF11214.3 EGG13011.1 - 0.0015 18.5 1.1 0.0033 17.4 0.8 1.5 1 0 0 1 1 1 1 Mediator complex subunit 2 ArfGap PF01412.13 EGG13012.1 - 3.7e-42 142.8 0.4 5.7e-42 142.2 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Acetyltransf_1 PF00583.19 EGG13013.1 - 0.00037 20.4 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGG13013.1 - 0.00098 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EGG13013.1 - 0.0015 18.6 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1180 PF06679.7 EGG13016.1 - 0.09 12.6 0.7 0.13 12.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Glyco_hydro_72 PF03198.9 EGG13017.1 - 2.3e-89 299.5 0.0 3.1e-89 299.0 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EGG13017.1 - 8.1e-13 48.6 0.2 2e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EGG13017.1 - 0.00059 18.8 0.0 0.00092 18.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF1675 PF07897.6 EGG13018.1 - 0.034 14.0 9.2 0.11 12.3 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1675) Spc97_Spc98 PF04130.8 EGG13019.1 - 9.1e-30 103.4 0.5 5e-29 101.0 0.0 2.2 2 1 0 2 2 2 1 Spc97 / Spc98 family Yae1_N PF09811.4 EGG13020.1 - 0.42 10.1 68.2 0.49 9.9 3.0 10.8 11 0 0 11 11 11 0 Essential protein Yae1, N terminal PUF PF00806.14 EGG13021.1 - 2.3e-23 80.2 0.1 0.00036 19.8 0.0 7.2 7 0 0 7 7 7 6 Pumilio-family RNA binding repeat GATase_4 PF13230.1 EGG13022.1 - 1.1e-19 70.2 0.0 3.5e-19 68.5 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGG13022.1 - 1.8e-08 34.4 0.0 3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EGG13022.1 - 7.1e-08 31.5 0.0 4e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Ebola_NP PF05505.7 EGG13024.1 - 0.052 11.6 0.5 0.067 11.2 0.3 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DBD_Tnp_Mut PF03108.10 EGG13025.1 - 0.12 11.9 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 MuDR family transposase NADH_B2 PF14813.1 EGG13027.1 - 0.00037 20.0 0.3 0.00044 19.8 0.2 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 SNARE_assoc PF09335.6 EGG13028.1 - 1.5e-14 54.2 8.3 1.5e-14 54.2 5.7 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein T2SM PF04612.7 EGG13028.1 - 0.072 12.8 0.2 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Pkinase PF00069.20 EGG13029.1 - 4e-23 81.8 0.0 4.2e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG13029.1 - 3.6e-10 39.3 0.0 3.7e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Amidase_5 PF05382.8 EGG13029.1 - 0.0069 16.0 0.1 0.0085 15.7 0.1 1.2 1 0 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase PIP49_C PF12260.3 EGG13029.1 - 0.03 13.7 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kdo PF06293.9 EGG13029.1 - 0.034 13.2 0.0 0.041 12.9 0.0 1.0 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MoaC PF01967.16 EGG13030.1 - 1.5e-38 131.4 2.6 1.5e-37 128.2 1.8 2.1 1 1 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EGG13030.1 - 2.4e-29 101.6 0.0 5.3e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EGG13030.1 - 2.1e-22 80.0 0.0 5.2e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EGG13030.1 - 1.3e-08 35.0 0.1 6e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EGG13030.1 - 4.4e-07 29.9 0.4 2.1e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 4Fe-4S single cluster domain FAD_binding_2 PF00890.19 EGG13031.1 - 1.5e-85 287.5 0.1 2.2e-85 287.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EGG13031.1 - 5.9e-22 77.2 0.2 3e-21 75.0 0.1 2.3 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EGG13031.1 - 8.5e-13 47.9 0.9 9.9e-12 44.4 0.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGG13031.1 - 3.1e-11 43.1 0.5 8.8e-10 38.4 0.1 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGG13031.1 - 1.2e-10 41.5 0.0 1.3e-08 35.0 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGG13031.1 - 8.6e-08 31.6 0.1 1.9e-07 30.5 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGG13031.1 - 1.1e-06 27.4 2.5 9.7e-05 21.0 0.0 3.3 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox_3 PF13738.1 EGG13031.1 - 3.1e-06 27.3 0.2 1.3e-05 25.3 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGG13031.1 - 6.3e-06 25.4 0.4 1.6e-05 24.1 0.3 1.6 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGG13031.1 - 1.2e-05 24.4 0.6 0.0013 17.8 0.2 2.4 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EGG13031.1 - 2.9e-05 23.0 0.6 0.0032 16.4 0.2 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EGG13031.1 - 7.1e-05 23.1 0.5 0.0074 16.6 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGG13031.1 - 0.00081 18.5 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EGG13031.1 - 0.0099 14.8 0.1 0.059 12.2 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EGG13031.1 - 0.018 14.7 0.1 0.21 11.3 0.1 2.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding GDI PF00996.13 EGG13031.1 - 0.034 12.4 0.1 0.057 11.7 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor NAD_binding_7 PF13241.1 EGG13031.1 - 0.04 14.1 0.0 0.082 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EGG13031.1 - 0.045 13.3 0.1 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MRVI1 PF05781.7 EGG13032.1 - 0.0021 16.5 0.6 0.0024 16.3 0.4 1.0 1 0 0 1 1 1 1 MRVI1 protein MFS_1 PF07690.11 EGG13033.1 - 2.1e-31 108.9 16.5 4.7e-28 97.9 10.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGG13033.1 - 1.7e-10 40.1 3.0 2.9e-10 39.3 2.1 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EGG13033.1 - 2.9e-07 29.0 0.6 4.3e-07 28.5 0.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGG13033.1 - 8.5e-05 21.1 5.2 0.00032 19.2 0.4 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EGG13033.1 - 0.71 9.7 0.0 0.71 9.7 0.0 3.2 3 1 0 3 3 3 0 MFS_1 like family UBN2_3 PF14244.1 EGG13034.1 - 0.015 14.8 0.1 0.13 11.7 0.0 2.3 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type GHMP_kinases_C PF08544.8 EGG13035.1 - 1.3e-06 28.5 0.0 3.9e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EGG13035.1 - 6.9e-06 26.0 3.8 4.9e-05 23.3 0.9 2.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain YqfD PF06898.6 EGG13039.1 - 0.11 11.1 0.1 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Pro_isomerase PF00160.16 EGG13040.1 - 1.7e-42 145.2 0.0 2e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1925 PF09094.6 EGG13043.1 - 0.0046 16.9 1.1 0.011 15.6 0.6 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1925) Mito_fiss_reg PF05308.6 EGG13043.1 - 0.12 11.7 2.6 0.17 11.2 1.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator NAM-associated PF14303.1 EGG13043.1 - 0.12 12.6 4.9 0.16 12.2 3.4 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Avl9 PF09794.4 EGG13046.1 - 1.3e-99 333.2 0.0 2.9e-78 262.9 0.0 3.0 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.5 EGG13046.1 - 4e-08 32.9 0.1 0.00076 19.1 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 EGG13046.1 - 4.6e-08 32.6 0.0 0.00099 18.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.7 EGG13046.1 - 7.5e-06 26.0 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.16 EGG13046.1 - 0.074 12.7 0.3 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 DENN (AEX-3) domain eIF3_subunit PF08597.5 EGG13047.1 - 1e-48 166.0 13.1 1.5e-48 165.4 9.1 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit TBX PF12598.3 EGG13047.1 - 1 9.8 10.8 0.062 13.6 3.2 2.1 2 0 0 2 2 2 0 T-box transcription factor VSG_B PF13206.1 EGG13047.1 - 5.7 5.9 13.6 1.3 8.1 7.2 1.5 2 0 0 2 2 2 0 Trypanosomal VSG domain SSrecog PF03531.9 EGG13048.1 - 3.6e-75 252.0 0.2 1.2e-73 247.0 0.2 2.8 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EGG13048.1 - 7.1e-22 77.2 0.1 3e-21 75.2 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF4597 PF15366.1 EGG13049.1 - 0.059 12.9 0.1 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Avian_gp85 PF03708.9 EGG13049.1 - 0.47 9.6 9.2 0.94 8.6 6.3 1.7 1 1 0 1 1 1 0 Avian retrovirus envelope protein, gp85 Corona_NS2 PF04753.7 EGG13049.1 - 3.6 7.5 5.9 1.2 9.1 1.6 1.9 1 1 1 2 2 2 0 Coronavirus non-structural protein NS2 zf-RING_5 PF14634.1 EGG13051.1 - 9.3e-05 22.0 7.6 0.00015 21.3 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain ADIP PF11559.3 EGG13051.1 - 0.14 12.0 0.7 0.26 11.1 0.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-RING_2 PF13639.1 EGG13051.1 - 2.5 7.9 8.0 4.5 7.1 5.6 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 EGG13051.1 - 8.6 6.3 9.1 0.13 12.1 1.4 1.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING MBOAT_2 PF13813.1 EGG13052.1 - 8.1e-08 32.2 0.9 8.1e-08 32.2 0.6 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family F_bP_aldolase PF01116.15 EGG13053.1 - 6.6e-97 324.0 0.0 7.5e-97 323.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II LeuA_dimer PF08502.5 EGG13053.1 - 0.16 11.7 0.7 0.32 10.7 0.5 1.4 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain TB2_DP1_HVA22 PF03134.14 EGG13054.1 - 2.3e-25 88.1 5.7 2.5e-25 88.0 3.0 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Taeniidae_ag PF05596.6 EGG13054.1 - 0.11 12.2 0.2 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Taeniidae antigen PXB PF12828.2 EGG13058.1 - 0.00019 21.0 0.8 0.0023 17.5 0.1 2.6 2 1 0 2 2 2 1 PX-associated Ecl1 PF12855.2 EGG13059.1 - 0.0018 17.5 2.2 0.0033 16.6 1.5 1.4 1 0 0 1 1 1 1 Life-span regulatory factor CLTH PF10607.4 EGG13060.1 - 5.2e-15 55.4 0.0 9.7e-14 51.2 0.0 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EGG13060.1 - 0.0044 16.7 0.0 0.0084 15.8 0.0 1.5 1 0 0 1 1 1 1 LisH CENP-C_C PF11699.3 EGG13061.1 - 1.2e-21 76.4 0.0 2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 EGG13061.1 - 0.0024 18.4 24.8 0.17 12.4 7.6 4.6 4 1 0 4 4 4 2 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Methyltransf_26 PF13659.1 EGG13062.1 - 1.5e-12 47.5 0.0 2.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGG13062.1 - 3.3e-10 39.6 0.0 5.7e-10 38.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGG13062.1 - 0.0079 16.5 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGG13062.1 - 0.05 14.0 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EGG13062.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 EGG13062.1 - 0.075 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Tom5 PF10642.4 EGG13063.1 - 0.01 15.4 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase CHCH PF06747.8 EGG13064.1 - 1.2e-05 25.0 0.7 2e-05 24.3 0.5 1.4 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.4 EGG13064.1 - 4.2e-05 23.7 11.2 5.4e-05 23.3 7.8 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DEC-1_N PF04625.8 EGG13064.1 - 0.19 10.3 2.9 0.21 10.2 2.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF1903 PF08991.5 EGG13064.1 - 0.25 11.5 2.2 0.44 10.7 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Inositol_P PF00459.20 EGG13067.1 - 1.7e-48 165.2 0.0 4.3e-47 160.6 0.0 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family Barwin PF00967.12 EGG13068.1 - 0.00042 19.9 0.2 0.00084 19.0 0.0 1.6 2 0 0 2 2 2 1 Barwin family DPBB_1 PF03330.13 EGG13068.1 - 0.00079 19.3 0.1 0.0045 16.9 0.1 2.2 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel BNR PF02012.15 EGG13068.1 - 0.0019 17.7 1.5 0.012 15.2 0.0 3.1 3 0 0 3 3 3 1 BNR/Asp-box repeat Pollen_allerg_1 PF01357.16 EGG13068.1 - 0.004 16.9 0.1 0.004 16.9 0.1 1.8 2 0 0 2 2 2 1 Pollen allergen BNR_2 PF13088.1 EGG13068.1 - 0.0091 15.3 0.2 0.012 14.8 0.2 1.2 1 0 0 1 1 1 1 BNR repeat-like domain DUF2235 PF09994.4 EGG13069.1 - 5e-52 176.9 0.0 6.2e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_2 PF02230.11 EGG13069.1 - 0.14 11.5 0.1 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MSC PF09402.5 EGG13070.1 - 1.1e-60 205.1 0.7 1.7e-60 204.4 0.5 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EGG13070.1 - 4.6e-05 22.8 0.1 0.00012 21.4 0.1 1.8 1 0 0 1 1 1 1 HeH/LEM domain MethyltransfD12 PF02086.10 EGG13070.1 - 0.0033 16.9 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Cpn60_TCP1 PF00118.19 EGG13072.1 - 1.1e-17 63.7 0.2 1.3e-17 63.6 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PDGLE PF13190.1 EGG13077.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 PDGLE domain Alpha_kinase PF02816.13 EGG13078.1 - 6.8e-06 25.8 0.6 1e-05 25.2 0.4 1.3 1 0 0 1 1 1 1 Alpha-kinase family NSP2-B_epitope PF14757.1 EGG13080.1 - 0.026 13.9 1.5 0.045 13.2 1.0 1.4 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein PDT PF00800.13 EGG13080.1 - 0.13 11.8 3.0 0.19 11.2 1.3 1.9 1 1 0 1 1 1 0 Prephenate dehydratase Lumazine_bd PF12870.2 EGG13080.1 - 0.35 10.9 8.6 3 7.9 1.1 3.4 2 2 2 4 4 4 0 Lumazine-binding domain Phage_Mu_Gam PF07352.7 EGG13080.1 - 2.6 7.5 9.5 11 5.5 2.2 3.1 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein DUF87 PF01935.12 EGG13080.1 - 2.9 7.6 13.0 1.9 8.2 6.0 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF87 HEAT PF02985.17 EGG13081.1 - 1.1e-07 31.3 5.5 0.17 12.0 0.0 6.3 5 1 1 6 6 6 3 HEAT repeat Pkinase PF00069.20 EGG13081.1 - 0.00018 20.7 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.1 EGG13081.1 - 0.0063 16.7 0.2 5.7 7.2 0.0 3.2 2 1 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EGG13081.1 - 0.04 14.4 0.9 6.8 7.3 0.0 4.1 2 1 2 4 4 4 0 HEAT-like repeat Pkinase_Tyr PF07714.12 EGG13081.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Methyltransf_15 PF09445.5 EGG13083.1 - 3.4e-44 150.3 0.1 6.5e-43 146.1 0.1 2.0 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EGG13083.1 - 1.2e-12 47.8 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EGG13083.1 - 7.3e-11 41.9 0.0 1.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 EGG13083.1 - 9.9e-11 41.4 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGG13083.1 - 1.1e-08 35.5 0.0 2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGG13083.1 - 2.2e-08 34.3 0.0 3.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGG13083.1 - 1.5e-07 31.1 0.0 2.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EGG13083.1 - 2.5e-07 30.2 0.0 3.4e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.9 EGG13083.1 - 3.5e-06 26.5 0.0 5.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EGG13083.1 - 5.7e-06 26.7 0.0 9.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EGG13083.1 - 0.00042 19.4 0.0 0.00065 18.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 EGG13083.1 - 0.003 16.7 0.1 0.0044 16.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF43 PF01861.11 EGG13083.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_5 PF01795.14 EGG13083.1 - 0.0073 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family Methyltransf_24 PF13578.1 EGG13083.1 - 0.022 15.6 0.0 0.039 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.11 EGG13083.1 - 0.029 13.3 0.0 0.037 12.9 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase TPMT PF05724.6 EGG13083.1 - 0.031 13.7 0.1 0.059 12.8 0.1 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) ADH_zinc_N PF00107.21 EGG13083.1 - 0.039 13.5 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase N6_Mtase PF02384.11 EGG13083.1 - 0.048 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase tRNA_U5-meth_tr PF05958.6 EGG13083.1 - 0.12 11.0 0.1 0.21 10.2 0.0 1.4 1 1 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF633 PF04816.7 EGG13083.1 - 0.12 11.6 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF633) Cutinase PF01083.17 EGG13084.1 - 9e-26 90.6 2.5 1.1e-25 90.4 1.7 1.1 1 0 0 1 1 1 1 Cutinase CBM_21 PF03370.8 EGG13086.1 - 2.5e-27 95.0 0.1 4.9e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 EGG13086.1 - 0.12 12.4 0.4 0.61 10.2 0.2 2.1 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) AIRC PF00731.15 EGG13087.1 - 6e-62 207.3 1.9 1.1e-61 206.4 1.3 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EGG13087.1 - 1.2e-42 145.1 0.0 1.9e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EGG13087.1 - 1.5e-08 34.6 0.0 0.0016 18.1 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGG13087.1 - 0.0019 17.0 0.0 0.0054 15.5 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon 2-Hacid_dh_C PF02826.14 EGG13087.1 - 0.0021 17.2 0.0 0.13 11.4 0.0 2.6 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_D2 PF02786.12 EGG13087.1 - 0.0039 16.5 0.0 0.0074 15.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EGG13087.1 - 0.036 13.9 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain DUF1297 PF06973.7 EGG13087.1 - 0.05 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) Histone PF00125.19 EGG13088.1 - 5.4e-31 106.5 0.4 8.6e-31 105.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGG13088.1 - 7.9e-05 22.7 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGG13088.1 - 0.002 18.1 0.1 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PRAI PF00697.17 EGG13088.1 - 0.053 13.0 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Bromo_TP PF07524.8 EGG13088.1 - 0.056 13.1 0.1 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 EGG13088.1 - 0.11 12.2 0.2 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit WD40 PF00400.27 EGG13089.1 - 3e-55 182.2 21.3 3.2e-12 45.8 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EGG13089.1 - 2.9e-07 30.4 0.0 0.0025 17.5 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A adh_short PF00106.20 EGG13090.1 - 3.9e-23 82.1 0.6 1.5e-22 80.3 0.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG13090.1 - 1.6e-16 60.8 0.1 2.7e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG13090.1 - 4.2e-09 36.3 2.5 1.6e-08 34.4 1.7 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGG13090.1 - 0.00014 21.3 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 EGG13090.1 - 0.00039 19.8 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family Pyr_redox PF00070.22 EGG13090.1 - 0.0024 18.2 0.6 0.0051 17.1 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.10 EGG13090.1 - 0.016 14.1 0.3 0.026 13.4 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EGG13090.1 - 0.019 14.6 0.5 0.034 13.7 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EGG13090.1 - 0.046 12.2 0.7 0.74 8.2 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein AdoHcyase_NAD PF00670.16 EGG13090.1 - 0.069 12.9 0.2 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.1 EGG13090.1 - 0.075 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 EGG13091.1 - 1.9e-19 70.2 0.2 6.1e-19 68.5 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGG13091.1 - 1.8e-15 57.3 0.2 4.3e-15 56.1 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGG13091.1 - 6.8e-08 32.3 0.1 3.1e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 KR domain Glyco_tran_WecB PF03808.8 EGG13091.1 - 0.00039 19.8 0.0 0.00099 18.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Pyr_redox PF00070.22 EGG13091.1 - 0.038 14.3 0.9 0.1 12.9 0.5 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGG13091.1 - 0.081 12.5 0.3 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Histone PF00125.19 EGG13092.1 - 4.1e-14 52.4 0.1 5e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGG13092.1 - 3.8e-05 23.7 0.0 5e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EGG13092.1 - 0.00011 22.0 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EGG13092.1 - 0.0013 18.7 0.1 0.0026 17.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGG13092.1 - 0.047 12.9 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T ELMO_CED12 PF04727.8 EGG13093.1 - 5.3e-25 87.9 0.0 1e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family YfhO PF09586.5 EGG13096.1 - 0.25 9.3 0.4 0.32 8.9 0.3 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Maf1 PF09174.5 EGG13096.1 - 5.5 6.8 6.3 0.38 10.5 0.5 1.9 2 1 0 2 2 2 0 Maf1 regulator Hormone_5 PF00184.12 EGG13099.1 - 0.25 11.9 5.6 0.061 13.8 1.4 1.9 1 1 1 2 2 2 0 Neurohypophysial hormones, C-terminal Domain Vps54 PF07928.7 EGG13101.1 - 1.5e-50 170.8 2.5 1.5e-50 170.8 1.7 2.3 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 EGG13101.1 - 1.3e-05 24.3 0.3 1.3e-05 24.3 0.2 3.1 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) zf-RING_2 PF13639.1 EGG13103.1 - 9.9e-10 38.0 5.8 1.6e-09 37.4 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGG13103.1 - 7.5e-05 22.3 3.7 0.00015 21.4 2.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGG13103.1 - 0.0011 18.6 2.4 0.002 17.7 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGG13103.1 - 0.0015 18.4 6.2 0.0028 17.6 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG13103.1 - 0.041 13.5 1.8 0.11 12.2 1.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGG13103.1 - 0.094 12.5 0.4 4.6 7.1 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EGG13103.1 - 0.26 11.3 2.2 0.61 10.1 1.5 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EGG13103.1 - 2.2 8.0 6.8 0.63 9.8 0.5 2.4 2 0 0 2 2 2 0 RING-type zinc-finger STAG PF08514.6 EGG13104.1 - 1.9e-08 34.0 0.4 4.1e-08 32.9 0.3 1.5 1 0 0 1 1 1 1 STAG domain TPR_MLP1_2 PF07926.7 EGG13104.1 - 0.0046 16.6 0.1 0.0046 16.6 0.1 2.2 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein HEAT PF02985.17 EGG13104.1 - 0.078 13.1 0.0 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 HEAT repeat DUF4119 PF13494.1 EGG13104.1 - 0.18 11.7 6.7 0.12 12.3 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF4119) RasGEF_N PF00618.15 EGG13104.1 - 2.5 8.2 7.0 0.2 11.7 0.3 2.4 2 1 0 2 2 2 0 RasGEF N-terminal motif DUF3350 PF11830.3 EGG13107.1 - 0.0038 17.2 0.9 0.0052 16.7 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3350) DUF445 PF04286.7 EGG13109.1 - 0.28 10.6 1.7 0.32 10.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF445) MAGE PF01454.14 EGG13111.1 - 9.6e-23 80.5 0.0 1.2e-19 70.4 0.0 2.2 2 0 0 2 2 2 2 MAGE family MatE PF01554.13 EGG13112.1 - 2.4e-43 147.5 30.9 1e-26 93.5 4.7 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EGG13112.1 - 2.1e-07 30.8 9.6 2.1e-07 30.8 6.7 3.8 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain GDA1_CD39 PF01150.12 EGG13113.1 - 2.6e-92 309.6 0.0 3.5e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family vATP-synt_AC39 PF01992.11 EGG13115.1 - 9.4e-102 340.5 0.0 1.1e-101 340.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit GMC_oxred_N PF00732.14 EGG13116.1 - 6.5e-37 127.2 0.0 9.1e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGG13116.1 - 2.7e-33 115.2 0.0 5e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EGG13116.1 - 0.2 10.4 0.8 0.72 8.6 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain DEAD PF00270.24 EGG13117.1 - 4.6e-39 133.6 0.0 3.7e-38 130.6 0.0 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGG13117.1 - 1.7e-22 79.0 0.1 4.9e-22 77.5 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EGG13117.1 - 5.1e-19 67.8 2.0 5.1e-19 67.8 1.4 3.0 3 0 0 3 3 3 1 DBP10CT (NUC160) domain DUF3715 PF12509.3 EGG13117.1 - 0.0074 16.1 0.7 0.0074 16.1 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3715) Voltage_CLC PF00654.15 EGG13118.1 - 2.6e-93 312.8 18.0 2.6e-93 312.8 12.5 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EGG13118.1 - 0.0016 18.2 0.0 0.016 14.9 0.0 2.5 2 0 0 2 2 2 1 CBS domain DUF3169 PF11368.3 EGG13118.1 - 0.11 11.6 0.3 0.31 10.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF1241 PF06840.6 EGG13120.1 - 0.02 14.1 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Cellulase PF00150.13 EGG13121.1 - 1.6e-11 43.9 0.0 2.4e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pribosyltran PF00156.22 EGG13122.1 - 3.3e-09 36.5 0.2 6.7e-08 32.3 0.1 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PIGA PF08288.7 EGG13123.1 - 5.2e-32 110.0 0.2 1.4e-31 108.6 0.1 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EGG13123.1 - 2.2e-26 92.3 0.0 3.6e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGG13123.1 - 1.6e-14 54.1 0.0 3.3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGG13123.1 - 3.5e-14 53.2 0.0 5.7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EGG13123.1 - 3.9e-10 39.7 0.0 2.8e-09 36.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EGG13123.1 - 3.8e-05 23.8 0.0 8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EGG13123.1 - 0.1 12.0 0.1 2.2 7.7 0.0 2.1 1 1 0 2 2 2 0 Starch synthase catalytic domain Pribosyltran PF00156.22 EGG13125.1 - 4e-09 36.2 0.1 2e-08 33.9 0.1 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PIGA PF08288.7 EGG13126.1 - 3.4e-32 110.6 0.2 9.2e-32 109.2 0.1 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EGG13126.1 - 2.2e-26 92.3 0.0 3.6e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGG13126.1 - 1.6e-14 54.1 0.0 3.3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGG13126.1 - 2e-14 54.0 0.0 3.2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EGG13126.1 - 3.6e-10 39.8 0.0 2.1e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EGG13126.1 - 3.8e-05 23.8 0.0 8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EGG13126.1 - 0.1 12.0 0.1 2.2 7.7 0.0 2.1 1 1 0 2 2 2 0 Starch synthase catalytic domain DUF1616 PF07760.6 EGG13127.1 - 0.089 11.9 0.2 4 6.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1616) Sugar_tr PF00083.19 EGG13128.1 - 4.5e-98 328.7 26.4 5.2e-98 328.5 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGG13128.1 - 3.8e-23 81.7 61.6 3.3e-21 75.4 23.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Helicase_C PF00271.26 EGG13129.1 - 9.9e-21 73.4 0.2 1.4e-18 66.5 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGG13129.1 - 1.4e-16 60.5 0.0 2.9e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.5 EGG13129.1 - 5.2e-07 29.3 0.0 1.9e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 RQC domain ResIII PF04851.10 EGG13129.1 - 0.036 13.8 0.0 0.13 12.1 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Med18 PF09637.5 EGG13130.1 - 0.1 12.0 0.0 0.21 11.1 0.0 1.5 1 1 0 1 1 1 0 Med18 protein DUF3195 PF11424.3 EGG13131.1 - 0.13 12.4 0.1 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) FAD_binding_4 PF01565.18 EGG13133.1 - 8.5e-22 77.1 1.9 1.4e-21 76.4 0.4 2.0 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.7 EGG13133.1 - 4.6e-08 32.8 0.1 8.8e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.14 EGG13133.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain WD40 PF00400.27 EGG13134.1 - 5e-26 89.5 14.7 3.1e-08 33.1 0.0 6.2 6 1 0 6 6 6 5 WD domain, G-beta repeat DUF1921 PF09081.5 EGG13134.1 - 0.16 11.9 3.6 39 4.2 0.2 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF1921) DUF2205 PF10224.4 EGG13136.1 - 1.2e-13 50.4 0.9 1.3e-13 50.3 0.6 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) TACC PF05010.9 EGG13136.1 - 0.00018 21.3 0.7 0.00019 21.3 0.5 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) CENP-F_leu_zip PF10473.4 EGG13136.1 - 0.00037 20.3 0.3 0.00043 20.1 0.2 1.0 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 EGG13136.1 - 0.003 17.3 1.2 0.0038 17.0 0.9 1.1 1 0 0 1 1 1 1 Tropomyosin like CCDC155 PF14662.1 EGG13136.1 - 0.0045 16.6 0.5 0.0049 16.4 0.4 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 DivIC PF04977.10 EGG13136.1 - 0.0045 16.4 1.8 0.0078 15.6 0.6 1.7 1 1 1 2 2 2 2 Septum formation initiator Ax_dynein_light PF10211.4 EGG13136.1 - 0.0059 16.4 0.7 0.0073 16.1 0.5 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Sas10_Utp3 PF04000.10 EGG13136.1 - 0.0067 16.5 0.1 0.01 16.0 0.1 1.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family GAS PF13851.1 EGG13136.1 - 0.0069 15.6 0.2 0.0077 15.4 0.2 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Dor1 PF04124.7 EGG13136.1 - 0.0079 14.7 0.7 0.0085 14.5 0.5 1.0 1 0 0 1 1 1 1 Dor1-like family ADIP PF11559.3 EGG13136.1 - 0.0085 16.0 1.0 0.0098 15.8 0.7 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.10 EGG13136.1 - 0.0087 15.8 2.5 0.076 12.8 0.2 2.2 1 1 0 2 2 2 1 Basic region leucine zipper FlxA PF14282.1 EGG13136.1 - 0.012 15.5 1.2 0.014 15.3 0.8 1.1 1 0 0 1 1 1 0 FlxA-like protein APG6 PF04111.7 EGG13136.1 - 0.018 14.1 1.2 0.016 14.2 0.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 EGG13136.1 - 0.022 13.4 1.3 0.024 13.2 0.9 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_I PF06008.9 EGG13136.1 - 0.023 14.0 0.9 0.027 13.8 0.6 1.0 1 0 0 1 1 1 0 Laminin Domain I bZIP_1 PF00170.16 EGG13136.1 - 0.033 14.1 1.9 0.77 9.7 0.1 2.3 1 1 2 3 3 3 0 bZIP transcription factor TPR_MLP1_2 PF07926.7 EGG13136.1 - 0.036 13.7 1.3 0.069 12.8 0.9 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.6 EGG13136.1 - 0.037 13.7 1.0 0.049 13.3 0.7 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 IncA PF04156.9 EGG13136.1 - 0.041 13.4 1.0 0.041 13.4 0.7 1.1 1 0 0 1 1 1 0 IncA protein HAUS5 PF14817.1 EGG13136.1 - 0.043 12.3 0.5 0.045 12.3 0.4 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Syntaxin PF00804.20 EGG13136.1 - 0.049 13.7 0.5 0.066 13.3 0.3 1.3 1 0 0 1 1 1 0 Syntaxin HALZ PF02183.13 EGG13136.1 - 0.054 13.2 1.4 4.3 7.1 0.2 2.3 1 1 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 EGG13136.1 - 0.058 13.7 1.0 0.075 13.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 EGG13136.1 - 0.069 12.4 0.4 0.073 12.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2576 PF10845.3 EGG13136.1 - 0.073 12.2 0.1 0.16 11.1 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2576) Phage_GP20 PF06810.6 EGG13136.1 - 0.075 12.4 1.7 0.13 11.7 1.2 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF641 PF04859.7 EGG13136.1 - 0.09 12.5 0.2 0.099 12.4 0.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Syntaxin-6_N PF09177.6 EGG13136.1 - 0.092 13.1 0.8 0.1 12.9 0.5 1.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Anti-adapt_IraP PF10796.4 EGG13136.1 - 0.1 13.0 0.3 0.14 12.5 0.2 1.3 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein Reo_sigmaC PF04582.7 EGG13136.1 - 0.13 11.3 0.5 0.14 11.3 0.3 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TSC22 PF01166.13 EGG13136.1 - 0.15 12.0 0.4 0.29 11.1 0.3 1.5 1 1 0 1 1 1 0 TSC-22/dip/bun family RhoGAP PF00620.22 EGG13139.1 - 3.9e-32 110.9 0.0 7.2e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 EGG13139.1 - 5.1e-20 71.8 0.4 9e-19 67.8 0.1 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain ORC6 PF05460.8 EGG13139.1 - 3.2 6.7 9.3 0.89 8.5 4.3 1.6 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Ribonuc_red_lgC PF02867.10 EGG13141.1 - 4.1e-211 702.2 0.0 1.5e-210 700.3 0.0 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EGG13141.1 - 4.9e-24 83.9 0.1 1.2e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EGG13141.1 - 1.6e-16 60.5 0.1 4.9e-16 58.9 0.1 1.9 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 EGG13141.1 - 0.0041 15.2 0.0 0.007 14.4 0.0 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase PPR_2 PF13041.1 EGG13142.1 - 4.9e-05 23.2 0.0 0.0084 16.0 0.0 3.5 3 1 1 4 4 4 1 PPR repeat family SDH_beta PF03315.10 EGG13142.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.7 1 1 0 1 1 1 0 Serine dehydratase beta chain TPR_14 PF13428.1 EGG13142.1 - 0.13 12.9 0.0 3.9 8.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SDH_alpha PF03313.10 EGG13143.1 - 2.4e-92 308.9 0.6 3.9e-92 308.2 0.4 1.3 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 EGG13143.1 - 9.3e-51 172.0 0.0 1.7e-50 171.1 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain UL40 PF10682.4 EGG13144.1 - 0.068 12.6 0.2 0.087 12.3 0.2 1.2 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 DUF1077 PF06417.7 EGG13145.1 - 2.9e-40 136.4 2.7 4.4e-40 135.9 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) SAM_decarbox PF01536.11 EGG13146.1 - 1.1e-91 306.9 0.0 1.6e-91 306.4 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase CFEM PF05730.6 EGG13147.1 - 6.3e-09 35.5 15.1 9e-09 35.0 10.5 1.2 1 0 0 1 1 1 1 CFEM domain WD40 PF00400.27 EGG13148.1 - 4.6e-34 115.0 0.0 1.9e-09 37.0 0.0 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGG13148.1 - 0.00087 18.1 0.3 0.42 9.3 0.0 2.7 1 1 2 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 EGG13148.1 - 0.0016 17.9 0.3 0.0088 15.5 0.1 2.0 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.3 EGG13148.1 - 0.0038 15.4 1.6 0.025 12.7 0.2 2.3 1 1 2 3 3 3 1 Nucleoporin Nup120/160 DUF2846 PF11008.3 EGG13148.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2846) YTH PF04146.10 EGG13149.1 - 1.6e-44 150.9 0.0 2.6e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 EGG13149.1 - 1.7e-06 27.5 0.0 5.3e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGG13149.1 - 0.0008 19.3 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGG13149.1 - 0.087 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.22 EGG13151.1 - 1.2e-75 249.2 0.1 8.7e-26 89.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pro_isomerase PF00160.16 EGG13152.1 - 1.8e-41 141.9 0.0 2.6e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L9_C PF03948.9 EGG13152.1 - 0.26 11.4 3.1 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain zf-HIT PF04438.11 EGG13153.1 - 0.71 9.5 9.3 1.6 8.4 6.5 1.6 1 0 0 1 1 1 0 HIT zinc finger DUF3052 PF11253.3 EGG13154.1 - 0.031 13.8 1.5 0.047 13.2 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3052) tRNA_NucTransf2 PF09249.6 EGG13156.1 - 0.016 15.0 0.2 0.034 14.0 0.1 1.6 1 1 0 1 1 1 0 tRNA nucleotidyltransferase, second domain DUF2063 PF09836.4 EGG13156.1 - 0.16 11.9 2.7 0.45 10.5 1.9 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) RCC1 PF00415.13 EGG13159.1 - 2.8e-30 104.2 8.9 3e-13 49.7 0.1 4.0 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGG13159.1 - 2.4e-15 55.6 15.6 1.8e-11 43.3 0.5 4.0 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Methyltransf_23 PF13489.1 EGG13160.1 - 0.01 15.5 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain PP1_bind PF15276.1 EGG13160.1 - 0.038 13.9 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein phosphatase 1 binding HgmA PF04209.8 EGG13160.1 - 0.082 11.2 0.1 0.1 10.9 0.1 1.2 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Med22 PF06179.7 EGG13161.1 - 3.9e-11 42.9 1.1 3.9e-11 42.9 0.7 1.5 2 0 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF1116 PF06545.6 EGG13161.1 - 0.025 13.6 0.1 0.029 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) PMC2NT PF08066.7 EGG13161.1 - 0.07 13.4 0.3 0.54 10.5 0.0 2.4 1 1 2 3 3 3 0 PMC2NT (NUC016) domain Mad3_BUB1_I PF08311.7 EGG13162.1 - 1.6e-30 105.4 0.3 2.6e-30 104.7 0.2 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Matrilin_ccoil PF10393.4 EGG13162.1 - 0.043 13.1 0.1 0.11 11.8 0.1 1.7 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Cellulase PF00150.13 EGG13163.1 - 3.7e-14 52.6 0.0 5.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sec7_N PF12783.2 EGG13164.1 - 4.2e-40 136.9 0.3 4.2e-40 136.9 0.2 2.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGG13164.1 - 0.1 12.1 0.0 1.6 8.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) DUF4336 PF14234.1 EGG13165.1 - 4e-12 45.9 0.1 5.1e-07 29.1 0.0 2.7 1 1 0 2 2 2 2 Domain of unknown function (DUF4336) zf-DHHC PF01529.15 EGG13166.1 - 2.7e-36 124.5 7.7 2.7e-36 124.5 5.4 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase Pkinase PF00069.20 EGG13167.1 - 6.7e-76 254.8 0.0 7.5e-76 254.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGG13167.1 - 5.4e-43 146.9 0.0 6.4e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGG13167.1 - 9.7e-09 34.5 0.0 3.6e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGG13167.1 - 0.00097 18.2 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGG13167.1 - 0.0068 16.1 0.3 0.37 10.4 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Dmrt1 PF12374.3 EGG13170.1 - 0.19 12.1 7.2 0.3 11.4 5.0 1.3 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Keratin PF02422.11 EGG13170.1 - 1.5 8.8 5.6 3.8 7.5 3.0 1.9 1 1 1 2 2 2 0 Keratin AAA PF00004.24 EGG13171.1 - 5.1e-97 321.1 0.0 2.1e-47 160.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EGG13171.1 - 6e-20 70.9 0.5 1.7e-19 69.5 0.4 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EGG13171.1 - 1.3e-13 50.5 0.0 2.1e-05 23.6 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EGG13171.1 - 1.5e-13 51.0 0.0 1.2e-07 31.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EGG13171.1 - 3.2e-13 49.7 0.0 1.5e-06 28.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGG13171.1 - 6e-12 45.4 0.4 1.9e-05 24.3 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGG13171.1 - 1.1e-11 45.5 0.0 0.0002 22.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGG13171.1 - 3.1e-11 43.5 0.1 0.0022 18.1 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGG13171.1 - 5.5e-10 39.5 0.0 0.0011 19.0 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 EGG13171.1 - 4.3e-09 35.5 0.0 0.0013 17.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 EGG13171.1 - 3.4e-08 32.8 0.0 0.0074 15.3 0.0 2.7 3 0 0 3 3 3 2 Zeta toxin IstB_IS21 PF01695.12 EGG13171.1 - 3.8e-08 32.9 0.0 0.0039 16.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein CDC48_2 PF02933.12 EGG13171.1 - 8e-08 31.8 0.0 1.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_25 PF13481.1 EGG13171.1 - 1.1e-07 31.4 3.3 0.016 14.6 0.0 3.8 2 2 1 4 4 4 2 AAA domain AAA_14 PF13173.1 EGG13171.1 - 1.6e-07 31.2 0.0 0.0095 15.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EGG13171.1 - 2.1e-07 30.6 0.9 0.009 15.7 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 EGG13171.1 - 3.3e-07 29.6 0.3 0.023 13.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EGG13171.1 - 1e-06 28.8 0.0 0.016 15.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EGG13171.1 - 1.5e-06 28.5 0.0 0.034 14.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 EGG13171.1 - 1.7e-06 27.8 0.1 1.9e-05 24.4 0.0 2.6 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain KaiC PF06745.8 EGG13171.1 - 2.1e-06 27.0 0.5 0.63 9.1 0.0 3.4 2 1 1 3 3 3 2 KaiC AAA_28 PF13521.1 EGG13171.1 - 3.8e-06 26.9 0.1 0.11 12.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 EGG13171.1 - 5.4e-06 26.3 0.0 0.0054 16.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EGG13171.1 - 8.2e-06 24.8 0.1 0.0081 15.0 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EGG13171.1 - 1.1e-05 24.5 0.0 0.0032 16.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EGG13171.1 - 2e-05 24.9 0.0 0.11 12.8 0.0 3.5 2 1 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 EGG13171.1 - 2.1e-05 24.0 0.0 0.34 10.3 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 EGG13171.1 - 3e-05 23.6 0.1 0.11 12.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain PhoH PF02562.11 EGG13171.1 - 4.2e-05 22.8 0.2 0.23 10.6 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Arch_ATPase PF01637.13 EGG13171.1 - 7.3e-05 22.5 0.0 1.6 8.4 0.0 3.4 2 1 1 3 3 3 1 Archaeal ATPase Sigma54_activ_2 PF14532.1 EGG13171.1 - 8e-05 22.7 0.0 0.41 10.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 EGG13171.1 - 9.1e-05 22.1 0.0 0.42 10.2 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_11 PF13086.1 EGG13171.1 - 0.00021 20.9 0.0 0.45 10.0 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EGG13171.1 - 0.00022 20.8 0.0 0.6 9.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGG13171.1 - 0.00041 20.0 0.2 0.51 9.9 0.0 3.5 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 EGG13171.1 - 0.00074 18.5 0.0 0.37 9.7 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EGG13171.1 - 0.001 18.7 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EGG13171.1 - 0.0015 18.2 1.4 1.2 8.8 0.0 4.1 4 0 0 4 4 4 1 NTPase T2SE PF00437.15 EGG13171.1 - 0.0024 16.8 0.0 0.17 10.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EGG13171.1 - 0.0029 17.1 0.0 0.23 10.9 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EGG13171.1 - 0.003 16.4 0.0 0.22 10.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain CCDC14 PF15254.1 EGG13171.1 - 0.017 13.5 0.0 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 AAA_10 PF12846.2 EGG13171.1 - 0.037 13.4 1.9 5.2 6.4 0.0 3.9 4 1 0 5 5 4 0 AAA-like domain IPT PF01745.11 EGG13171.1 - 0.037 13.1 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KTI12 PF08433.5 EGG13171.1 - 0.038 13.1 0.0 7.5 5.6 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 EGG13171.1 - 0.048 13.2 0.1 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 EGG13171.1 - 0.069 13.0 0.5 7.6 6.3 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase MobB PF03205.9 EGG13171.1 - 0.093 12.4 0.2 9.4 5.9 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Zot PF05707.7 EGG13171.1 - 0.11 11.9 0.1 17 4.7 0.0 3.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.9 EGG13171.1 - 0.11 11.4 0.0 1.5 7.7 0.0 2.4 2 1 1 3 3 3 0 KAP family P-loop domain Aldolase_II PF00596.16 EGG13172.1 - 2.1e-45 154.5 0.0 2.7e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TPR_MLP1_2 PF07926.7 EGG13173.1 - 7.5e-21 74.2 16.3 7.5e-21 74.2 11.3 16.5 8 6 6 14 14 14 7 TPR/MLP1/MLP2-like protein Romo1 PF10247.4 EGG13174.1 - 2.7e-20 72.3 11.1 4.3e-20 71.6 7.7 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 RibD_C PF01872.12 EGG13175.1 - 1.2e-11 44.6 0.1 6.4e-05 22.6 0.0 2.1 1 1 1 2 2 2 2 RibD C-terminal domain DUF4214 PF13946.1 EGG13175.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) HAUS-augmin3 PF14932.1 EGG13177.1 - 7.8 5.5 12.5 0.87 8.7 5.0 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 zf-RING_2 PF13639.1 EGG13178.1 - 4.7e-09 35.9 6.1 4.7e-09 35.9 4.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EGG13178.1 - 7.5e-05 22.3 4.0 0.00012 21.7 2.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGG13178.1 - 0.00016 21.6 5.9 0.00027 20.9 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGG13178.1 - 0.00058 19.4 2.4 0.0011 18.6 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGG13178.1 - 0.0048 16.5 5.5 0.0086 15.7 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGG13178.1 - 0.04 13.5 4.8 0.07 12.7 3.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EGG13178.1 - 0.15 12.1 3.1 0.32 11.0 2.1 1.6 1 1 0 1 1 1 0 RING-variant domain zf-H2C2_2 PF13465.1 EGG13178.1 - 0.65 10.3 3.8 15 6.0 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING-like PF08746.6 EGG13178.1 - 0.68 9.9 4.9 1.6 8.8 3.4 1.7 1 1 0 1 1 1 0 RING-like domain PHD PF00628.24 EGG13178.1 - 1.4 8.6 5.6 3.8 7.2 3.9 1.8 1 1 0 1 1 1 0 PHD-finger AICARFT_IMPCHas PF01808.13 EGG13179.1 - 1.1e-104 349.9 0.0 1.5e-104 349.5 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EGG13179.1 - 1.7e-20 72.7 0.0 3.1e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Rhabdo_ncap PF00945.13 EGG13179.1 - 0.048 12.2 0.6 0.067 11.7 0.4 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein SUV3_C PF12513.3 EGG13181.1 - 5.7e-12 44.8 0.4 1.8e-11 43.2 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EGG13181.1 - 6.5e-08 32.3 0.0 1.5e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TK PF00265.13 EGG13181.1 - 0.14 11.7 0.0 0.4 10.2 0.0 1.7 1 1 0 1 1 1 0 Thymidine kinase RF-1 PF00472.15 EGG13182.1 - 2.4e-14 53.1 1.0 3e-14 52.7 0.7 1.1 1 0 0 1 1 1 1 RF-1 domain His_Phos_1 PF00300.17 EGG13183.1 - 1.2e-26 93.6 0.0 1.7e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) WD40 PF00400.27 EGG13184.1 - 3.7e-15 55.1 3.8 2.6e-05 23.8 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EGG13184.1 - 0.0069 16.1 0.0 0.52 9.9 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Mito_fiss_reg PF05308.6 EGG13185.1 - 0.92 8.8 14.8 1.2 8.4 8.4 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator MBOAT_2 PF13813.1 EGG13186.1 - 4.8e-13 48.9 1.6 6.4e-13 48.5 0.7 1.6 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family GMC_oxred_N PF00732.14 EGG13187.1 - 1.5e-62 211.4 0.0 1.9e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGG13187.1 - 1.1e-39 136.0 0.0 1.8e-39 135.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EGG13187.1 - 4.8e-06 25.6 0.1 0.0011 17.9 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGG13187.1 - 3.5e-05 22.8 0.6 0.00092 18.2 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGG13187.1 - 4e-05 23.5 0.2 0.00037 20.4 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGG13187.1 - 0.00038 20.5 0.0 0.087 12.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGG13187.1 - 0.0004 20.3 0.1 0.0015 18.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGG13187.1 - 0.00054 18.9 0.1 0.0011 17.9 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 EGG13187.1 - 0.0011 17.4 0.4 0.017 13.5 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 EGG13187.1 - 0.0095 15.0 0.1 0.03 13.4 0.1 1.7 2 0 0 2 2 2 1 Thi4 family GMC_oxred_N PF00732.14 EGG13189.1 - 7.4e-58 196.0 0.0 1e-57 195.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGG13189.1 - 3.4e-40 137.6 0.2 6.1e-40 136.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EGG13189.1 - 1.3e-05 24.2 1.2 0.00078 18.3 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EGG13189.1 - 0.00015 20.8 1.8 0.00073 18.5 0.7 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGG13189.1 - 0.0011 18.9 0.3 0.0032 17.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGG13189.1 - 0.0012 17.9 0.2 0.0021 17.0 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EGG13189.1 - 0.018 14.1 0.1 0.032 13.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EGG13189.1 - 0.039 12.4 0.2 0.069 11.6 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 EGG13189.1 - 0.068 13.2 0.3 0.44 10.5 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGG13189.1 - 0.12 12.2 0.5 0.26 11.1 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-MYND PF01753.13 EGG13190.1 - 6.2e-07 29.1 15.2 1.1e-06 28.3 10.5 1.4 1 0 0 1 1 1 1 MYND finger Bys1 PF04681.7 EGG13190.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Blastomyces yeast-phase-specific protein Peptidase_M50B PF13398.1 EGG13192.1 - 8.6e-27 93.8 12.3 8.6e-27 93.8 8.5 2.3 2 0 0 2 2 2 1 Peptidase M50B-like Peptidase_M50 PF02163.17 EGG13192.1 - 0.073 12.0 1.3 0.41 9.5 0.5 2.5 2 1 0 2 2 2 0 Peptidase family M50 PH_6 PF15406.1 EGG13194.1 - 0.037 14.0 0.1 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain DnaJ PF00226.26 EGG13195.1 - 5.2e-11 42.1 0.1 1.8e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain ATP-synt_DE PF00401.15 EGG13195.1 - 0.21 11.5 1.5 0.37 10.7 0.4 1.9 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain F-box-like PF12937.2 EGG13196.1 - 0.00011 21.8 0.1 0.00028 20.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGG13196.1 - 0.0035 16.9 0.2 0.02 14.5 0.2 2.2 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.2 EGG13196.1 - 0.25 11.0 2.0 8.6 6.1 0.0 3.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF1242 PF06842.7 EGG13197.1 - 2.3e-19 68.5 3.2 3.3e-19 68.0 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Lambda_Bor PF06291.6 EGG13198.1 - 0.079 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Bor protein NBP1 PF08537.5 EGG13200.1 - 0.0029 16.8 0.1 0.0067 15.6 0.1 1.6 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 DUF1220 PF06758.8 EGG13201.1 - 0.032 14.0 2.8 2.4 8.0 0.2 2.8 2 0 0 2 2 2 0 Repeat of unknown function (DUF1220) Tom22 PF04281.8 EGG13203.1 - 4e-34 117.0 0.4 4.3e-34 116.9 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF2387 PF09526.5 EGG13206.1 - 0.021 14.7 0.1 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Vps53_N PF04100.7 EGG13211.1 - 1.7e-71 241.0 0.0 3.5e-71 240.0 0.0 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal TPR_12 PF13424.1 EGG13212.1 - 0.00023 21.0 0.9 0.048 13.6 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGG13212.1 - 0.00052 19.6 0.0 0.0018 17.9 0.0 1.9 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 EGG13212.1 - 0.047 13.6 5.9 2.8 8.0 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat OPT PF03169.10 EGG13212.1 - 0.1 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein TPR_8 PF13181.1 EGG13212.1 - 0.15 11.8 6.3 16 5.5 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGG13212.1 - 1.8 8.2 4.9 10 5.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1640 PF07798.6 EGG13214.1 - 2.4e-16 60.2 0.2 2.7e-16 60.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) IncA PF04156.9 EGG13217.1 - 1.2 8.6 5.2 0.51 9.9 1.0 2.1 2 0 0 2 2 2 0 IncA protein Epimerase PF01370.16 EGG13219.1 - 4.8e-39 134.1 0.0 2.3e-29 102.4 0.0 2.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGG13219.1 - 7.7e-20 70.8 0.5 2.2e-19 69.3 0.4 1.7 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EGG13219.1 - 1.8e-16 59.7 1.1 1.8e-09 36.6 0.5 3.0 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase_Csub PF13950.1 EGG13219.1 - 4.8e-15 55.2 0.0 8.6e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 EGG13219.1 - 1.2e-12 47.3 1.4 3.3e-06 26.2 0.3 2.7 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGG13219.1 - 2.4e-08 33.2 0.0 8.4e-07 28.1 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EGG13219.1 - 0.00052 19.9 0.0 0.0033 17.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EGG13219.1 - 0.00072 19.6 0.0 0.1 12.6 0.0 2.5 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EGG13219.1 - 0.0018 17.5 0.2 0.006 15.8 0.1 1.9 1 1 0 1 1 1 1 NmrA-like family KR PF08659.5 EGG13219.1 - 0.0025 17.4 0.0 0.12 11.9 0.0 2.4 2 1 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.19 EGG13219.1 - 0.11 12.8 0.0 0.65 10.3 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain LRR_4 PF12799.2 EGG13220.1 - 0.03 13.9 1.8 2 8.1 0.2 4.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGG13220.1 - 0.18 11.5 1.2 2.3 8.0 0.2 3.2 4 0 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 EGG13220.1 - 2.5 7.8 5.5 9 6.1 3.8 2.1 1 1 0 1 1 1 0 F-box-like Spore_YhaL PF14147.1 EGG13223.1 - 0.56 9.6 4.3 1.3 8.5 0.4 3.0 3 0 0 3 3 3 0 Sporulation protein YhaL zf-CCHC PF00098.18 EGG13226.1 - 0.012 15.5 1.7 0.022 14.6 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Pterin_4a PF01329.14 EGG13226.1 - 0.066 12.9 0.5 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase Adaptin_N PF01602.15 EGG13227.1 - 1.1e-17 63.5 5.1 5e-16 58.1 3.6 2.0 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGG13227.1 - 0.29 10.9 2.6 23 4.7 0.0 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Rad60-SLD PF11976.3 EGG13228.1 - 6.8e-13 48.1 0.6 1.2e-09 37.7 0.9 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ETF_alpha PF00766.14 EGG13230.1 - 5.6e-35 118.8 0.8 1.5e-34 117.4 0.1 2.0 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EGG13230.1 - 8.8e-34 116.5 0.0 1.2e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DnaJ PF00226.26 EGG13231.1 - 2e-14 53.0 0.4 6.2e-14 51.4 0.3 1.8 1 1 0 1 1 1 1 DnaJ domain Glycos_transf_2 PF00535.21 EGG13232.1 - 0.0039 16.9 4.0 0.16 11.6 0.3 2.6 1 1 1 2 2 2 2 Glycosyl transferase family 2 UvsY PF11056.3 EGG13233.1 - 0.091 12.8 0.6 0.12 12.4 0.4 1.2 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY DUF381 PF04038.7 EGG13233.1 - 0.13 12.3 0.1 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF381) PDH PF02153.12 EGG13235.1 - 1.4e-13 50.3 0.0 1.9e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EGG13235.1 - 7.5e-07 29.4 0.0 1.8e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EGG13235.1 - 5.8e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EGG13235.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EGG13235.1 - 0.033 14.2 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EGG13235.1 - 0.056 12.8 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 EGG13236.1 - 5.4e-28 97.7 23.1 5.4e-28 97.7 16.0 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Cbl_N2 PF02761.9 EGG13236.1 - 0.094 12.7 2.1 0.42 10.7 0.0 2.9 3 1 1 4 4 4 0 CBL proto-oncogene N-terminus, EF hand-like domain Ribosomal_S10 PF00338.17 EGG13237.1 - 5.2e-32 109.5 0.3 6e-32 109.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ChaC PF04752.7 EGG13239.1 - 1.6e-55 187.7 0.0 1.9e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein DUF4038 PF13204.1 EGG13239.1 - 0.0004 19.8 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) AIG2_2 PF13772.1 EGG13239.1 - 0.0088 16.1 0.2 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 AIG2-like family XkdW PF09636.5 EGG13245.1 - 0.0053 16.6 0.8 0.02 14.7 0.5 2.0 1 0 0 1 1 1 1 XkdW protein Ribosomal_L37 PF08561.5 EGG13246.1 - 5e-21 74.0 0.0 6.8e-21 73.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 RmlD_sub_bind PF04321.12 EGG13248.1 - 3.7e-20 71.9 0.1 9.2e-18 64.1 0.1 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EGG13248.1 - 4.9e-06 26.1 0.0 0.00022 20.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGG13248.1 - 0.0037 16.2 0.0 0.9 8.3 0.0 2.0 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGG13249.1 - 1.2e-05 24.4 0.0 1.5e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain UNC-93 PF05978.11 EGG13250.1 - 2.4e-15 56.3 4.1 6.7e-15 54.9 2.8 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EGG13250.1 - 1.9e-10 40.0 30.4 1.9e-10 40.0 21.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF500 PF04366.7 EGG13250.1 - 0.049 13.0 0.4 0.32 10.4 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF500) NfeD PF01957.13 EGG13250.1 - 1.6 8.8 6.6 17 5.5 1.1 3.0 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding ABC2_membrane_5 PF13346.1 EGG13250.1 - 5.3 6.2 16.3 0.041 13.1 4.5 2.4 3 0 0 3 3 3 0 ABC-2 family transporter protein HPP PF04982.8 EGG13251.1 - 2e-25 88.9 4.3 3.1e-25 88.3 3.0 1.3 1 0 0 1 1 1 1 HPP family La PF05383.12 EGG13252.1 - 2e-07 30.7 0.3 0.00017 21.2 0.1 2.5 2 0 0 2 2 2 2 La domain Mesd PF10185.4 EGG13252.1 - 0.027 14.1 0.2 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor PPTA PF01239.17 EGG13253.1 - 1.9e-35 118.7 23.2 1.3e-09 36.9 0.2 6.5 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat K_oxygenase PF13434.1 EGG13254.1 - 2.6e-07 29.9 0.0 0.019 13.9 0.0 3.8 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EGG13254.1 - 0.00049 20.2 0.3 0.063 13.3 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGG13254.1 - 0.0061 16.3 0.1 2.5 7.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding zf-CCHC PF00098.18 EGG13255.1 - 0.0028 17.5 2.3 0.0052 16.6 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 EGG13255.1 - 0.019 14.7 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type