# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- MFS_1 PF07690.16 CCU97295.1 - 8e-19 67.8 35.0 5.8e-18 64.9 29.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ANAPC4_WD40 PF12894.7 CCU97296.1 - 2.5e-06 27.7 0.1 0.017 15.4 0.0 4.6 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCU97296.1 - 0.00073 20.3 12.7 1.3 10.0 0.2 6.0 5 2 0 5 5 5 2 WD domain, G-beta repeat PALB2_WD40 PF16756.5 CCU97296.1 - 0.055 12.4 0.1 0.086 11.7 0.1 1.2 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain PACT_coil_coil PF10495.9 CCU97297.1 - 1.2e-05 25.8 0.5 1.2e-05 25.8 0.5 3.0 2 1 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF3584 PF12128.8 CCU97297.1 - 0.55 7.7 53.2 0.081 10.4 30.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3584) Phage_GP20 PF06810.11 CCU97297.1 - 8.9 6.1 21.1 0.081 12.7 5.6 3.2 3 1 1 4 4 4 0 Phage minor structural protein GP20 ADIP PF11559.8 CCU97298.1 - 0.0033 17.5 2.2 0.0033 17.5 2.2 3.1 3 1 1 4 4 4 2 Afadin- and alpha -actinin-Binding DUF3349 PF11829.8 CCU97298.1 - 2.8 8.8 6.8 2 9.2 3.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) MatP_C PF17414.2 CCU97298.1 - 5.2 7.3 7.9 1.9 8.8 1.2 3.5 3 2 1 4 4 4 0 MatP C-terminal ribbon-helix-helix domain Sugar_tr PF00083.24 CCU97300.1 - 1.4e-20 73.6 22.5 7.1e-19 68.0 22.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter WD40 PF00400.32 CCU97301.1 - 3.5e-27 94.1 13.6 0.00013 22.7 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU97301.1 - 1.6e-09 37.9 0.9 0.019 15.2 0.0 4.0 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 CCU97301.1 - 0.0022 17.4 1.1 1.3 8.2 0.0 3.0 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 CCU97301.1 - 0.011 14.5 0.4 0.1 11.2 0.2 2.5 2 1 0 3 3 3 0 Nucleoporin Nup120/160 CHCH PF06747.13 CCU97302.1 - 1.8e-07 31.1 3.6 3.1e-07 30.3 3.6 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 CCU97302.1 - 0.00027 21.3 1.6 0.00042 20.7 1.6 1.3 1 0 0 1 1 1 1 GCK domain Porin_10 PF14121.6 CCU97303.1 - 0.22 10.0 1.9 0.31 9.6 1.9 1.1 1 0 0 1 1 1 0 Putative porin DUF2807 PF10988.8 CCU97303.1 - 0.78 9.5 11.8 5.8 6.7 11.8 2.2 1 1 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Ytp1 PF10355.9 CCU97304.1 - 4.2e-58 196.7 26.0 1.1e-56 192.1 19.5 3.2 2 1 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CCU97304.1 - 7.7e-21 73.9 2.0 7.7e-21 73.9 2.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) SAM_2 PF07647.17 CCU97305.1 - 2e-15 56.6 0.0 3.5e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CCU97305.1 - 6.6e-15 55.3 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 CCU97305.1 - 2.3e-07 30.3 0.1 9.3e-07 28.4 0.1 2.1 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCU97305.1 - 0.00013 21.7 0.1 0.00049 19.9 0.1 2.0 1 0 0 1 1 1 1 Variant SH3 domain RA PF00788.23 CCU97305.1 - 0.00022 21.8 0.0 0.00044 20.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_PNT PF02198.16 CCU97305.1 - 0.015 15.3 0.1 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 CCU97305.1 - 0.21 11.4 0.0 0.53 10.1 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Sec7 PF01369.20 CCU97306.1 - 1.5e-14 54.1 0.0 2.1e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain Cullin PF00888.22 CCU97307.1 - 3.2e-12 45.9 0.0 7.6e-12 44.6 0.0 1.5 2 0 0 2 2 2 1 Cullin family RmlD_sub_bind PF04321.17 CCU97308.1 - 4.6e-54 183.5 0.1 1e-53 182.4 0.1 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain Vps5 PF09325.10 CCU97308.1 - 1.6e-41 142.4 5.4 2.5e-41 141.8 5.4 1.2 1 0 0 1 1 1 1 Vps5 C terminal like Epimerase PF01370.21 CCU97308.1 - 4.2e-28 98.4 0.6 6.1e-28 97.9 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PX PF00787.24 CCU97308.1 - 2.5e-21 75.8 0.0 6e-21 74.6 0.0 1.6 2 0 0 2 2 2 1 PX domain GDP_Man_Dehyd PF16363.5 CCU97308.1 - 4.9e-16 59.0 0.2 5.8e-15 55.5 0.2 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CCU97308.1 - 3e-11 43.0 0.2 6.7e-09 35.3 0.0 2.6 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CCU97308.1 - 1.5e-10 40.7 0.0 4.3e-08 32.6 0.0 2.7 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 CCU97308.1 - 1.9e-07 30.4 0.0 9.9e-07 28.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CCU97308.1 - 0.0023 17.8 0.6 0.0098 15.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 CCU97308.1 - 0.0055 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family Arfaptin PF06456.13 CCU97308.1 - 0.038 13.5 0.2 0.038 13.5 0.2 1.7 2 0 0 2 2 2 0 Arfaptin-like domain adh_short PF00106.25 CCU97308.1 - 0.15 11.5 0.9 0.52 9.7 0.9 1.9 1 1 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 CCU97308.1 - 0.18 11.9 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 CCU97308.1 - 0.27 11.1 2.2 3.2 7.6 0.3 3.0 2 1 1 3 3 3 0 KR domain Cir_N PF10197.9 CCU97308.1 - 0.48 10.7 3.1 1.5 9.0 3.1 1.9 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR FAM184 PF15665.5 CCU97308.1 - 1.4 8.7 8.4 1.3 8.8 4.8 2.2 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B STAS_2 PF13466.6 CCU97308.1 - 2 8.8 11.9 5.4 7.4 2.8 3.9 4 0 0 4 4 3 0 STAS domain 60KD_IMP PF02096.20 CCU97310.1 - 3.2e-28 98.7 0.7 4.2e-28 98.3 0.7 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein DUF1569 PF07606.11 CCU97310.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) Alanine_zipper PF11839.8 CCU97310.1 - 0.1 13.0 9.6 0.13 12.7 4.5 2.4 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein TBP PF00352.21 CCU97311.1 - 9.4e-66 217.8 0.1 3.4e-32 110.3 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CCU97311.1 - 1.2e-05 25.3 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 CCU97311.1 - 0.15 11.9 0.1 0.72 9.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) HSF_DNA-bind PF00447.17 CCU97312.1 - 2.7e-22 79.2 1.6 4.1e-22 78.6 0.6 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding SAP130_C PF16014.5 CCU97312.1 - 0.027 13.6 2.3 0.029 13.5 0.9 1.7 1 1 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Syntaxin_2 PF14523.6 CCU97312.1 - 0.21 12.0 7.1 3.3 8.1 0.2 2.9 2 0 0 2 2 2 0 Syntaxin-like protein SAM_3 PF18016.1 CCU97312.1 - 0.26 11.1 1.6 2.6 7.9 0.2 2.8 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) YabA PF06156.13 CCU97312.1 - 0.63 10.7 2.5 10 6.9 0.2 2.6 2 0 0 2 2 2 0 Initiation control protein YabA DUF948 PF06103.11 CCU97312.1 - 0.75 10.1 2.5 4.4 7.6 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 CCU97312.1 - 0.82 9.7 6.0 0.73 9.9 0.9 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Cortex-I_coil PF09304.10 CCU97312.1 - 0.88 9.8 3.1 0.58 10.4 0.6 2.0 2 0 0 2 2 2 0 Cortexillin I, coiled coil Muted PF14942.6 CCU97312.1 - 6.4 7.1 6.8 9.5 6.6 0.5 3.1 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein RNA_pol_Rpc82 PF05645.13 CCU97313.1 - 9.4e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 Death PF00531.22 CCU97313.1 - 0.034 14.3 0.9 0.11 12.7 0.9 1.9 1 1 0 1 1 1 0 Death domain TFIIE_alpha PF02002.17 CCU97313.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 TFIIE alpha subunit Cyto_heme_lyase PF01265.17 CCU97315.1 - 6.8e-39 134.2 13.2 1.6e-36 126.4 13.2 2.8 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Sld5 PF05916.11 CCU97316.1 - 6.2e-05 23.4 0.1 8.8e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein UPF0052 PF01933.18 CCU97317.1 - 0.011 15.0 0.3 0.082 12.1 0.0 2.1 1 1 0 2 2 2 0 Uncharacterised protein family UPF0052 tRNA_U5-meth_tr PF05958.11 CCU97318.1 - 3.3e-11 42.8 0.0 8.6e-11 41.4 0.0 1.6 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CCU97318.1 - 2.4e-06 27.4 0.0 4.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 CCU97318.1 - 6.2e-06 25.9 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 CCU97318.1 - 7.2e-06 26.6 0.0 1.5e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CCU97318.1 - 4.7e-05 22.9 0.0 7.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CCU97318.1 - 0.00018 22.1 0.0 0.00046 20.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCU97318.1 - 0.002 17.7 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TRM PF02005.16 CCU97318.1 - 0.014 14.6 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase TPMT PF05724.11 CCU97318.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 CCU97318.1 - 0.028 15.1 0.0 0.07 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CCU97318.1 - 0.037 13.9 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 CCU97318.1 - 0.074 12.5 0.0 0.39 10.2 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Met_10 PF02475.16 CCU97318.1 - 0.088 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein RhoGAP PF00620.27 CCU97319.1 - 9.4e-36 122.9 0.0 2.1e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Filament PF00038.21 CCU97319.1 - 0.074 12.6 3.8 0.12 12.0 3.8 1.2 1 0 0 1 1 1 0 Intermediate filament protein JIP_LZII PF16471.5 CCU97319.1 - 1.6 8.9 4.7 2.9 8.1 1.3 2.7 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II KH_1 PF00013.29 CCU97320.1 - 3.5e-29 100.4 0.1 2.3e-08 33.8 0.0 6.4 6 0 0 6 6 6 5 KH domain RNA_pol_Rpb5_N PF03871.14 CCU97321.1 - 2.6e-28 98.4 0.2 3.3e-28 98.1 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 CCU97321.1 - 0.00077 19.5 0.0 0.0012 18.8 0.0 1.6 1 1 0 1 1 1 1 Restriction endonuclease PqqD PF05402.12 CCU97321.1 - 0.075 13.3 0.1 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Mrr_cat_2 PF13156.6 CCU97321.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease NAD_binding_1 PF00175.21 CCU97322.1 - 5.1e-26 91.5 0.0 8.3e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CCU97322.1 - 2.7e-19 69.4 0.0 4.5e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CCU97322.1 - 5.5e-06 26.6 0.0 0.0057 16.8 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CCU97322.1 - 0.0003 21.0 0.0 0.032 14.4 0.0 2.4 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain ABC_ATPase PF09818.9 CCU97323.1 - 1.7e-131 439.1 0.0 2e-115 386.1 0.0 3.1 1 1 2 3 3 3 3 Predicted ATPase of the ABC class AAA_25 PF13481.6 CCU97323.1 - 0.00032 20.3 0.0 0.00077 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Chitin_synth_2 PF03142.15 CCU97324.1 - 6.1e-228 757.7 0.0 8.7e-228 757.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CCU97324.1 - 1.5e-13 51.2 0.3 1.5e-11 44.7 0.1 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CCU97324.1 - 2.3e-11 44.0 3.4 2.3e-11 44.0 3.4 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 CCU97324.1 - 0.011 15.2 0.2 2.4 7.6 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 LapA_dom PF06305.11 CCU97324.1 - 7.5 6.5 13.4 10 6.0 0.1 3.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain BAH PF01426.18 CCU97325.1 - 6.9e-12 45.3 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 BAH domain Bromodomain PF00439.25 CCU97325.1 - 1e-10 41.5 0.0 2.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain tRNA-synt_1b PF00579.25 CCU97327.1 - 3.2e-22 79.2 0.0 9.2e-22 77.7 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Vmethyltransf PF01660.17 CCU97327.1 - 0.065 12.1 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Viral methyltransferase LSM PF01423.22 CCU97328.1 - 3.5e-14 52.2 0.0 4.4e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCU97328.1 - 0.0012 19.0 0.1 0.0013 18.8 0.1 1.2 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF150_C PF17384.2 CCU97328.1 - 0.061 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain FAM216B PF15107.6 CCU97328.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 FAM216B protein family Avl9 PF09794.9 CCU97329.1 - 3e-96 322.4 0.1 3.6e-96 322.1 0.1 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 CCU97329.1 - 3.3e-05 23.8 0.3 0.0042 17.0 0.0 2.7 3 0 0 3 3 3 1 Stabilization of polarity axis DUF2347 PF09804.9 CCU97329.1 - 0.00084 19.0 0.7 0.0029 17.2 0.7 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 CCU97329.1 - 0.044 13.7 1.0 8 6.4 0.0 3.1 3 1 0 3 3 3 0 DENN (AEX-3) domain Holin_9 PF16936.5 CCU97329.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative holin Fibrillarin PF01269.17 CCU97330.1 - 6.5e-109 362.4 0.0 8e-109 362.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CCU97330.1 - 1e-05 25.3 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 CCU97330.1 - 0.0086 15.8 0.1 0.013 15.3 0.1 1.3 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 CCU97330.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CCU97330.1 - 0.036 14.2 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Tubulin PF00091.25 CCU97331.1 - 4.6e-67 226.0 0.0 6.5e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CCU97331.1 - 1.9e-44 150.8 0.5 2.8e-44 150.3 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CCU97331.1 - 3.6e-06 27.3 0.0 8.8e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CCU97331.1 - 0.048 12.9 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Ion_trans PF00520.31 CCU97332.1 - 2e-37 128.8 28.6 6.5e-23 81.2 16.1 2.1 2 0 0 2 2 2 2 Ion transport protein Chlorophyllase2 PF12740.7 CCU97332.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme AP2 PF00847.20 CCU97332.1 - 0.19 12.0 5.2 0.22 11.8 3.9 1.8 2 0 0 2 2 2 0 AP2 domain PKD_channel PF08016.12 CCU97332.1 - 1.1 7.9 23.4 0.99 8.0 4.4 2.6 2 1 0 2 2 2 0 Polycystin cation channel Ion_trans PF00520.31 CCU97333.1 - 3e-49 167.4 28.4 1e-24 87.1 2.4 2.1 2 0 0 2 2 2 2 Ion transport protein GPHH PF16905.5 CCU97333.1 - 0.0015 18.2 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PAP1 PF08601.10 CCU97333.1 - 4.1 7.0 8.1 6.8 6.3 8.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 BCS1_N PF08740.11 CCU97334.1 - 1.4e-54 184.9 0.0 2.1e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CCU97334.1 - 2.3e-08 34.5 0.0 4.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MgtE PF01769.16 CCU97335.1 - 7.7e-33 113.5 5.2 3.2e-18 66.3 3.9 3.2 2 1 1 3 3 3 2 Divalent cation transporter PCI PF01399.27 CCU97336.1 - 1.4e-09 38.4 0.1 1.4e-09 38.4 0.1 2.9 4 0 0 4 4 4 1 PCI domain Peptidase_M15_2 PF05951.13 CCU97336.1 - 1.8 8.2 4.7 3.7 7.2 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF882) DUF382 PF04037.13 CCU97337.1 - 9.6e-57 190.6 0.1 9.6e-57 190.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 CCU97337.1 - 1.2e-16 60.2 5.5 1.2e-16 60.2 5.5 2.2 2 0 0 2 2 2 1 PSP Nop14 PF04147.12 CCU97337.1 - 1.1 7.4 8.8 2.2 6.4 8.8 1.4 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 CCU97337.1 - 2.6 6.0 13.5 4.2 5.4 13.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi PTPRCAP PF15713.5 CCU97337.1 - 5 7.4 16.4 2.1 8.6 10.9 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 CCU97337.1 - 5.6 6.3 12.3 0.74 9.2 7.2 1.9 2 0 0 2 2 2 0 SDA1 RXT2_N PF08595.11 CCU97337.1 - 5.7 6.9 7.5 0.9 9.6 2.7 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal Proteasome PF00227.26 CCU97338.1 - 1.7e-50 171.2 0.1 2.1e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CCU97338.1 - 3.5e-09 35.9 0.4 3.5e-09 35.9 0.4 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Rio2_N PF09202.11 CCU97338.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Rio2, N-terminal Pyr_redox_2 PF07992.14 CCU97339.1 - 6.3e-36 124.1 0.0 7.7e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 CCU97339.1 - 4.5e-15 55.4 0.0 8.6e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 CCU97339.1 - 1.3e-10 41.6 0.1 2.2e-07 31.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 CCU97339.1 - 2.4e-06 27.4 0.0 4.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.6 CCU97339.1 - 0.0014 17.9 0.1 4.1 6.6 0.6 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 CCU97339.1 - 0.0042 17.6 0.0 0.0096 16.5 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal FAD_binding_2 PF00890.24 CCU97339.1 - 0.016 14.3 0.2 0.21 10.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain EF-hand_4 PF12763.7 CCU97340.1 - 3.3e-35 120.2 0.0 1.2e-13 50.9 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CCU97340.1 - 1e-08 35.5 0.0 0.0014 19.0 0.1 4.4 5 0 0 5 5 4 1 EF-hand domain pair UBA PF00627.31 CCU97340.1 - 1.2e-07 31.4 0.0 6.3e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain EF-hand_1 PF00036.32 CCU97340.1 - 5.8e-06 25.5 0.0 0.043 13.4 0.0 4.1 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 CCU97340.1 - 0.00075 19.3 0.2 2.4 8.1 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain pair ATG16 PF08614.11 CCU97340.1 - 0.003 17.8 39.8 0.067 13.4 12.9 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) ERM PF00769.19 CCU97340.1 - 0.0033 17.3 23.0 0.006 16.4 23.0 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family EF-hand_6 PF13405.6 CCU97340.1 - 0.011 15.6 4.9 2 8.5 0.0 5.1 5 0 0 5 5 4 0 EF-hand domain Atg14 PF10186.9 CCU97340.1 - 0.019 14.0 16.6 0.031 13.3 16.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UBA_3 PF09288.10 CCU97340.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain DUF4200 PF13863.6 CCU97340.1 - 0.88 10.0 23.6 1.5 9.2 23.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Macoilin PF09726.9 CCU97340.1 - 0.88 8.0 10.7 1.3 7.5 10.7 1.2 1 0 0 1 1 1 0 Macoilin family GIT_CC PF16559.5 CCU97340.1 - 0.93 9.4 7.7 0.25 11.2 4.3 1.9 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor AAA_13 PF13166.6 CCU97340.1 - 1.4 7.5 15.2 2 7.0 15.2 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 CCU97340.1 - 1.9 6.3 14.7 2.6 5.8 14.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 CCU97340.1 - 2.7 7.8 25.1 1.6 8.5 4.4 3.4 2 1 1 3 3 3 0 Septum formation initiator MPS2 PF17060.5 CCU97340.1 - 2.8 7.1 11.2 4.1 6.6 11.2 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Synaptobrevin PF00957.21 CCU97340.1 - 3.1 7.6 5.4 6.9 6.5 5.4 1.5 1 0 0 1 1 1 0 Synaptobrevin Fez1 PF06818.15 CCU97340.1 - 4.7 7.6 26.4 3.6 8.0 11.2 1.9 1 1 1 2 2 2 0 Fez1 SlyX PF04102.12 CCU97340.1 - 4.8 7.9 29.9 0.38 11.4 7.4 3.8 1 1 2 3 3 3 0 SlyX SAGA-Tad1 PF12767.7 CCU97341.1 - 4.4e-34 118.2 0.0 9.1e-34 117.2 0.0 1.5 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit GET2 PF08690.10 CCU97341.1 - 0.12 12.0 0.4 0.23 11.1 0.4 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Pkinase PF00069.25 CCU97342.1 - 8.1e-58 195.9 0.0 1.1e-57 195.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97342.1 - 9e-39 133.3 0.0 1.3e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCU97342.1 - 9.9e-06 24.6 0.0 1.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CCU97342.1 - 9e-05 21.9 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCU97342.1 - 0.013 15.4 1.8 0.36 10.7 0.1 3.3 3 1 1 4 4 4 0 Phosphotransferase enzyme family SPRY PF00622.28 CCU97343.1 - 1.2e-18 67.4 0.0 4e-18 65.7 0.1 1.9 2 0 0 2 2 2 1 SPRY domain bZIP_1 PF00170.21 CCU97344.1 - 3.7e-06 26.9 8.6 8.9e-06 25.7 8.3 1.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CCU97344.1 - 0.28 11.3 10.1 0.46 10.6 7.0 2.3 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 CCU97344.1 - 0.58 10.7 5.0 1.2 9.7 5.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor KTI12 PF08433.10 CCU97345.1 - 6.4e-11 42.2 0.4 9.7e-06 25.2 0.0 4.0 3 1 1 4 4 4 3 Chromatin associated protein KTI12 DUF2407_C PF13373.6 CCU97345.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain MeaB PF03308.16 CCU97345.1 - 0.21 10.5 0.0 3.1 6.7 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DEAD PF00270.29 CCU97347.1 - 4e-45 153.7 0.0 1.2e-44 152.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU97347.1 - 1.5e-26 92.9 0.0 7.6e-26 90.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU97347.1 - 0.05 13.6 0.0 0.84 9.6 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF1729 PF08354.10 CCU97347.1 - 0.097 11.5 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) HeLo PF14479.6 CCU97347.1 - 0.2 11.5 1.5 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 Prion-inhibition and propagation PAP_assoc PF03828.19 CCU97348.1 - 1.4e-13 50.9 0.0 3.1e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase AAA PF00004.29 CCU97349.1 - 3.2e-34 118.2 0.0 4.2e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCU97349.1 - 4.7e-08 33.4 0.4 4.1e-07 30.4 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCU97349.1 - 7.6e-08 32.9 0.1 1.8e-07 31.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 CCU97349.1 - 2.7e-06 27.6 0.0 8.5e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 CCU97349.1 - 2.8e-05 23.8 0.4 0.018 14.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 CCU97349.1 - 2.9e-05 24.1 0.1 8e-05 22.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CCU97349.1 - 3.3e-05 24.5 0.0 5.1e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCU97349.1 - 5.4e-05 23.4 0.0 0.00011 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CCU97349.1 - 7e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 CCU97349.1 - 7.8e-05 22.5 0.2 0.0022 17.8 0.0 2.2 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CCU97349.1 - 0.00012 22.1 0.0 0.00021 21.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 CCU97349.1 - 0.00021 21.3 0.5 0.0016 18.4 0.4 2.2 1 1 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 CCU97349.1 - 0.00022 21.0 0.0 0.00046 20.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CCU97349.1 - 0.00041 20.7 0.0 0.0011 19.4 0.0 1.7 1 1 1 2 2 1 1 RNA helicase AAA_11 PF13086.6 CCU97349.1 - 0.00068 19.5 0.2 0.0015 18.3 0.2 1.8 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CCU97349.1 - 0.00099 19.1 0.1 0.76 9.6 0.1 2.1 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 CCU97349.1 - 0.001 18.8 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 CCU97349.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CCU97349.1 - 0.0016 18.2 0.0 0.0039 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 CCU97349.1 - 0.002 17.3 0.2 0.01 15.0 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 CCU97349.1 - 0.0022 18.2 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 CCU97349.1 - 0.0033 17.2 0.1 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase ABC_tran PF00005.27 CCU97349.1 - 0.0065 17.0 0.0 0.0098 16.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ALIX_LYPXL_bnd PF13949.6 CCU97349.1 - 0.0081 15.5 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV AAA_7 PF12775.7 CCU97349.1 - 0.0085 15.6 0.0 0.047 13.2 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region KAP_NTPase PF07693.14 CCU97349.1 - 0.0086 15.4 0.1 1.4 8.1 0.0 2.5 2 1 0 3 3 2 1 KAP family P-loop domain Rad17 PF03215.15 CCU97349.1 - 0.0097 15.8 0.2 0.058 13.3 0.0 2.0 1 1 1 2 2 2 1 Rad17 P-loop domain NTPase_1 PF03266.15 CCU97349.1 - 0.014 15.3 0.1 0.053 13.4 0.0 1.8 1 1 1 2 2 2 0 NTPase TIP49 PF06068.13 CCU97349.1 - 0.017 14.3 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CCU97349.1 - 0.023 14.1 0.0 0.077 12.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CCU97349.1 - 0.026 14.9 0.5 0.093 13.1 0.4 2.0 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 CCU97349.1 - 0.04 13.3 0.1 0.67 9.3 0.0 2.1 1 1 1 2 2 2 0 KaiC CPT PF07931.12 CCU97349.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 CCU97349.1 - 0.043 14.3 0.0 0.11 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CCU97349.1 - 0.045 13.6 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 CCU97349.1 - 0.053 12.2 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CCU97349.1 - 0.06 13.8 0.1 0.13 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CCU97349.1 - 0.067 13.3 0.2 0.63 10.2 0.2 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 CCU97349.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein PduV-EutP PF10662.9 CCU97349.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 CCU97349.1 - 0.085 12.2 0.1 0.78 9.0 0.0 1.9 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 CCU97349.1 - 0.09 12.0 0.0 0.51 9.6 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 CCU97349.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.9 CCU97349.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 CCU97349.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase WD40 PF00400.32 CCU97350.1 - 1.5e-23 82.7 4.1 1.3e-05 25.8 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU97350.1 - 9.1e-09 35.5 0.1 0.064 13.6 0.1 4.9 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCU97350.1 - 6.5e-05 22.4 0.3 0.00096 18.6 0.2 2.7 2 1 1 3 3 3 1 WD40-like domain eIF2A PF08662.11 CCU97350.1 - 0.013 15.4 2.4 0.32 10.8 0.4 3.0 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CCU97350.1 - 0.069 11.8 0.5 0.29 9.7 0.1 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CCU97350.1 - 0.11 11.5 0.7 1.4 7.8 0.2 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PP2C PF00481.21 CCU97351.1 - 5.1e-78 262.3 0.0 7.1e-78 261.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C HlyIII PF03006.20 CCU97352.1 - 2.7e-53 181.0 19.3 3.5e-53 180.6 19.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related Glyco_transf_4 PF13439.6 CCU97352.1 - 0.036 14.1 10.7 0.31 11.0 0.8 3.4 3 0 0 3 3 3 0 Glycosyltransferase Family 4 TAF8_C PF10406.9 CCU97353.1 - 2.1e-13 50.6 1.3 8.2e-13 48.7 0.1 2.5 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 CCU97353.1 - 1.1e-07 31.7 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 CCU97353.1 - 0.21 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Histone-fold protein E1-E2_ATPase PF00122.20 CCU97354.1 - 1.9e-40 138.3 14.0 9e-33 113.3 0.1 3.7 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CCU97354.1 - 6.1e-24 84.7 7.0 6.1e-24 84.7 7.0 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CCU97354.1 - 5.9e-20 72.5 0.0 2.1e-18 67.4 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCU97354.1 - 1.3e-17 63.6 0.0 2.5e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CCU97354.1 - 1.3e-16 60.0 0.0 3.5e-16 58.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCU97354.1 - 0.00067 19.5 0.1 0.0056 16.5 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 CCU97354.1 - 4.6 7.1 9.0 0.14 12.0 2.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) Rdx PF10262.9 CCU97356.1 - 7.7e-10 38.8 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Rdx family SIR2 PF02146.17 CCU97357.1 - 3.3e-24 85.8 0.0 2.2e-19 70.0 0.0 3.0 3 0 0 3 3 3 2 Sir2 family ETF PF01012.21 CCU97358.1 - 6.8e-46 156.4 9.5 1.2e-45 155.7 9.5 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 CCU97358.1 - 4.1e-33 113.3 2.2 4.5e-33 113.1 0.6 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Ku PF02735.16 CCU97359.1 - 7.7e-16 58.4 0.0 1.1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 CCU97359.1 - 1.9e-06 28.0 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Ku C terminal domain like Glyco_trans_1_4 PF13692.6 CCU97360.1 - 1.7e-08 35.0 0.0 3.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCU97360.1 - 4.2e-07 30.1 4.3 9.7e-07 28.9 4.3 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CCU97360.1 - 0.002 17.7 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CCU97360.1 - 0.028 14.8 0.6 0.066 13.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 Ufd2P_core PF10408.9 CCU97361.1 - 5e-194 646.4 0.0 5.9e-194 646.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CCU97361.1 - 5.7e-25 87.3 0.1 1.4e-24 86.1 0.1 1.7 1 0 0 1 1 1 1 U-box domain EIF_2_alpha PF07541.12 CCU97362.1 - 6.1e-39 132.7 1.2 4.4e-38 130.0 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CCU97362.1 - 4.1e-13 49.5 0.3 1.2e-12 48.0 0.3 1.9 1 0 0 1 1 1 1 S1 RNA binding domain Amidohydro_1 PF01979.20 CCU97362.1 - 0.022 14.1 0.2 0.033 13.5 0.2 1.2 1 0 0 1 1 1 0 Amidohydrolase family bMG3 PF11974.8 CCU97362.1 - 0.064 13.3 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial alpha-2-macroglobulin MG3 domain DUF4453 PF14627.6 CCU97362.1 - 0.083 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) DUF4312 PF14189.6 CCU97362.1 - 0.085 12.9 2.3 0.35 10.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4312) Cpn60_TCP1 PF00118.24 CCU97363.1 - 2.5e-154 514.6 2.5 2.8e-154 514.4 2.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.21 CCU97363.1 - 0.0028 17.8 0.6 0.027 14.6 0.1 2.6 3 0 0 3 3 3 1 Resolvase, N terminal domain Pro_isomerase PF00160.21 CCU97364.1 - 1.3e-48 165.3 0.0 2.8e-48 164.2 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CCU97364.1 - 3.6e-09 37.1 0.4 0.076 13.9 0.2 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CCU97364.1 - 0.0039 16.2 0.8 0.027 13.5 0.4 2.0 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 CCU97364.1 - 0.0075 16.6 0.0 6.7 7.1 0.0 3.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BCNT PF07572.12 CCU97365.1 - 8e-22 77.1 0.2 1.6e-21 76.1 0.2 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development Semialdhyde_dhC PF02774.18 CCU97366.1 - 1.7e-41 142.3 0.0 2.3e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 CCU97366.1 - 3e-13 50.3 0.0 8e-13 48.9 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 CCU97366.1 - 0.0061 17.3 0.2 0.02 15.6 0.0 2.0 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 CCU97366.1 - 0.02 15.0 0.0 0.05 13.7 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 CCU97366.1 - 0.042 14.1 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ILVD_EDD PF00920.21 CCU97367.1 - 1.3e-203 677.4 0.1 1.5e-203 677.2 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Ribosomal_L15e PF00827.17 CCU97370.1 - 1.7e-85 285.6 14.7 1.2e-84 282.8 14.7 1.9 1 1 0 1 1 1 1 Ribosomal L15 Ribosomal_L5e PF17144.4 CCU97371.1 - 9.1e-81 269.6 1.2 9.6e-81 269.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CCU97371.1 - 6.6e-35 119.9 4.2 6.6e-35 119.9 4.2 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 CCU97371.1 - 0.00051 20.4 0.3 0.0025 18.2 0.1 2.1 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Thr_synth_N PF14821.6 CCU97371.1 - 0.088 13.0 0.1 19 5.5 0.0 2.6 2 0 0 2 2 2 0 Threonine synthase N terminus MtrA PF04208.14 CCU97371.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A His_Phos_2 PF00328.22 CCU97372.1 - 1.8e-86 290.9 0.8 3.3e-45 155.1 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 CCU97373.1 - 7.9e-96 321.7 0.0 8.6e-50 170.2 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DOG1 PF14144.6 CCU97373.1 - 0.052 13.8 0.1 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Seed dormancy control Ski_Sno PF02437.17 CCU97373.1 - 0.06 13.1 0.0 12 5.7 0.0 3.2 3 0 0 3 3 3 0 SKI/SNO/DAC family ERG4_ERG24 PF01222.17 CCU97374.1 - 2.2e-92 310.1 6.5 2.3e-69 234.2 3.2 2.0 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CCU97374.1 - 8.2e-05 22.2 3.7 0.00012 21.6 3.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 CCU97374.1 - 0.0015 18.9 0.0 0.0037 17.6 0.0 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 CCU97374.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ras PF00071.22 CCU97376.1 - 1.9e-53 180.4 0.0 2.2e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCU97376.1 - 2.4e-20 72.9 0.0 3.3e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU97376.1 - 2.6e-06 27.0 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CCU97376.1 - 0.0048 16.3 0.0 0.0066 15.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CCU97376.1 - 0.0092 15.4 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GDA1_CD39 PF01150.17 CCU97377.1 - 1.3e-72 244.9 0.0 1.7e-58 198.3 0.0 2.0 1 1 1 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family DUF1644 PF07800.12 CCU97377.1 - 0.013 15.6 0.4 0.63 10.1 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1644) Ppx-GppA PF02541.16 CCU97377.1 - 0.12 11.8 0.1 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 Ppx/GppA phosphatase family DcpS_C PF11969.8 CCU97378.1 - 3.2e-26 92.0 0.0 4.3e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding TFCD_C PF12612.8 CCU97379.1 - 4.6e-23 82.0 0.2 4.6e-23 82.0 0.2 2.7 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal Vac14_Fab1_bd PF12755.7 CCU97379.1 - 0.025 15.2 0.1 9.4 6.9 0.0 3.5 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region DUF1815 PF08844.10 CCU97379.1 - 0.045 13.7 0.0 3.6 7.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1815) Hpt PF01627.23 CCU97380.1 - 6.9e-10 39.1 0.4 1.1e-09 38.4 0.1 1.6 2 0 0 2 2 2 1 Hpt domain TPR_16 PF13432.6 CCU97380.1 - 0.079 13.6 3.7 1.2 9.8 0.8 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat PspA_IM30 PF04012.12 CCU97380.1 - 0.082 12.5 0.2 0.62 9.6 0.0 1.9 2 0 0 2 2 2 0 PspA/IM30 family MINDY_DUB PF04424.13 CCU97381.1 - 3.9e-25 88.1 0.0 6.3e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase Peptidase_M24 PF00557.24 CCU97382.1 - 2.5e-18 66.5 0.3 5e-18 65.5 0.3 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 Pkinase PF00069.25 CCU97383.1 - 6.6e-38 130.6 0.0 1.2e-37 129.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97383.1 - 5.4e-11 42.3 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCU97383.1 - 0.0003 20.8 0.1 0.0003 20.8 0.1 3.5 4 2 0 4 4 4 1 Phosphotransferase enzyme family Kinetochor_Ybp2 PF08568.10 CCU97383.1 - 0.0013 17.3 0.0 0.0025 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Choline_kinase PF01633.20 CCU97383.1 - 0.0023 17.5 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 CCU97383.1 - 0.054 12.8 0.1 1.3 8.3 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_2 PF07724.14 CCU97384.1 - 2.4e-46 158.0 0.0 1.7e-42 145.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CCU97384.1 - 1e-31 108.9 3.1 2e-30 104.8 0.3 2.6 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 CCU97384.1 - 1.5e-26 92.2 2.6 2.4e-26 91.6 0.2 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CCU97384.1 - 2.5e-18 66.8 0.0 4.8e-09 36.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CCU97384.1 - 1e-12 48.2 0.1 2e-07 31.1 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CCU97384.1 - 5.6e-09 35.9 0.2 1.5e-06 28.0 0.1 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 CCU97384.1 - 2.4e-07 31.3 3.8 0.00027 21.3 0.1 4.1 2 2 1 4 4 4 1 AAA ATPase domain AAA_14 PF13173.6 CCU97384.1 - 2.8e-06 27.4 0.0 0.039 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CCU97384.1 - 9.6e-06 25.2 0.2 0.18 11.3 0.1 3.0 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 CCU97384.1 - 9.7e-06 25.9 3.6 0.062 13.6 0.1 4.2 4 2 0 4 4 3 2 AAA domain AAA_30 PF13604.6 CCU97384.1 - 1.6e-05 24.7 0.4 0.035 13.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 CCU97384.1 - 2.1e-05 24.6 0.1 0.31 10.9 0.0 3.2 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea TniB PF05621.11 CCU97384.1 - 0.00022 20.7 0.0 0.01 15.3 0.0 2.9 2 1 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 CCU97384.1 - 0.00043 19.7 1.4 2 7.7 0.1 3.7 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CCU97384.1 - 0.00062 20.1 0.0 0.57 10.6 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 CCU97384.1 - 0.0015 19.0 0.1 1.5 9.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 CCU97384.1 - 0.0018 17.9 0.0 2.2 7.8 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 CCU97384.1 - 0.002 17.9 0.3 0.4 10.4 0.0 2.9 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_6 PF12774.7 CCU97384.1 - 0.0033 16.5 0.0 0.19 10.7 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_28 PF13521.6 CCU97384.1 - 0.0048 17.2 1.4 3.6 7.8 0.0 3.9 3 1 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 CCU97384.1 - 0.011 15.1 0.0 0.3 10.3 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 CCU97384.1 - 0.011 15.7 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CCU97384.1 - 0.012 15.6 0.0 0.61 10.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 CCU97384.1 - 0.013 15.9 0.1 5.5 7.3 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 CCU97384.1 - 0.013 16.0 4.9 80 3.6 7.6 3.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CCU97384.1 - 0.036 14.2 0.1 4.9 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 CCU97384.1 - 0.041 13.7 0.0 0.73 9.6 0.0 2.8 2 1 0 2 2 2 0 DNA polymerase III, delta subunit Roc PF08477.13 CCU97384.1 - 0.045 14.0 0.0 5.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_3 PF07726.11 CCU97384.1 - 0.047 13.5 0.1 0.58 10.0 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 CCU97384.1 - 0.063 13.3 0.1 7.7 6.5 0.0 3.7 4 1 1 5 5 5 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 CCU97384.1 - 0.067 12.9 0.0 15 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 CCU97384.1 - 0.078 11.9 0.2 15 4.3 0.0 2.9 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain DUF4094 PF13334.6 CCU97384.1 - 0.16 12.4 2.0 0.49 10.8 0.4 2.6 2 1 0 2 2 1 0 Domain of unknown function (DUF4094) Macoilin PF09726.9 CCU97384.1 - 0.31 9.6 3.4 0.47 9.0 3.4 1.2 1 0 0 1 1 1 0 Macoilin family YlqD PF11068.8 CCU97384.1 - 5.4 7.4 9.0 9.4 6.6 7.0 2.4 2 1 0 2 2 2 0 YlqD protein Atg14 PF10186.9 CCU97384.1 - 8 5.4 8.0 14 4.7 8.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BCIP PF13862.6 CCU97385.1 - 3.2e-37 128.3 0.0 4.3e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein NIF PF03031.18 CCU97386.1 - 7e-54 181.8 0.2 1.1e-53 181.2 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PRK PF00485.18 CCU97387.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.4 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CHCH PF06747.13 CCU97388.1 - 4.7e-05 23.4 3.8 6.7e-05 22.9 3.8 1.2 1 0 0 1 1 1 1 CHCH domain Succ_CoA_lig PF13607.6 CCU97388.1 - 0.027 14.3 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain RIBIOP_C PF04950.12 CCU97389.1 - 3.1e-94 315.7 0.0 3.1e-94 315.7 0.0 1.7 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CCU97389.1 - 1.3e-31 108.5 0.0 3.9e-31 107.0 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 CCU97389.1 - 5.8e-06 26.8 4.7 6.1e-06 26.7 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain GTP_EFTU PF00009.27 CCU97389.1 - 0.00019 21.0 0.0 0.017 14.6 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CCU97389.1 - 0.00038 20.7 0.0 0.0012 19.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 CCU97389.1 - 0.0042 16.8 0.0 0.013 15.2 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 CCU97389.1 - 0.0042 17.5 0.0 0.01 16.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 CCU97389.1 - 0.0049 16.8 0.5 0.01 15.7 0.0 1.7 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CCU97389.1 - 0.0058 17.2 1.7 0.013 16.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 CCU97389.1 - 0.0075 16.3 0.0 0.03 14.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 CCU97389.1 - 0.0097 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 CCU97389.1 - 0.0098 16.3 0.0 0.041 14.3 0.0 2.0 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 CCU97389.1 - 0.01 15.1 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 CCU97389.1 - 0.013 15.7 4.1 0.065 13.4 0.0 3.5 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 CCU97389.1 - 0.022 14.3 0.2 0.074 12.6 0.0 1.9 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 CCU97389.1 - 0.028 14.4 0.0 0.087 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CCU97389.1 - 0.081 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Roc PF08477.13 CCU97389.1 - 0.15 12.3 0.8 0.39 10.9 0.0 2.2 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 CCU97389.1 - 0.25 11.6 0.0 0.25 11.6 0.0 3.0 4 0 0 4 4 3 0 AAA domain RsgA_GTPase PF03193.16 CCU97389.1 - 0.48 10.3 3.9 0.93 9.4 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 CCU97389.1 - 0.57 10.7 0.0 0.57 10.7 0.0 2.3 3 0 0 3 3 1 0 AAA domain Nipped-B_C PF12830.7 CCU97390.1 - 2.6e-30 105.8 3.4 5.1e-26 91.8 0.4 2.4 1 1 1 2 2 2 2 Sister chromatid cohesion C-terminus Myc_target_1 PF15179.6 CCU97391.1 - 0.019 14.9 0.2 0.019 14.9 0.2 1.7 2 0 0 2 2 2 0 Myc target protein 1 OPT PF03169.15 CCU97392.1 - 3.7e-143 478.4 37.8 4.4e-143 478.1 37.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Hydrolase_6 PF13344.6 CCU97393.1 - 5e-20 71.5 0.0 1.5e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCU97393.1 - 1.7e-17 63.2 0.0 8.3e-17 61.0 0.0 2.1 1 1 0 1 1 1 1 HAD-hyrolase-like HA2 PF04408.23 CCU97396.1 - 2.7e-21 75.9 0.0 2.7e-21 75.9 0.0 2.8 4 0 0 4 4 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCU97396.1 - 2.6e-11 43.8 0.0 2.3e-10 40.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CCU97396.1 - 1.6e-08 34.7 0.0 3.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CCU97396.1 - 1.2e-07 31.6 0.0 3.1e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCU97396.1 - 1.3e-06 28.8 0.0 3.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCU97396.1 - 0.0015 18.3 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCU97396.1 - 0.0029 18.0 0.1 0.0076 16.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CCU97396.1 - 0.0077 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 CCU97396.1 - 0.0087 15.2 0.0 0.025 13.7 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 CCU97396.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 CCU97396.1 - 0.015 15.8 0.0 0.015 15.8 0.0 2.4 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CCU97396.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ResIII PF04851.15 CCU97396.1 - 0.096 12.7 0.0 2.9 7.9 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit vATP-synt_AC39 PF01992.16 CCU97397.1 - 4.4e-108 361.8 0.3 5.4e-108 361.5 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Acyl_CoA_thio PF02551.15 CCU97397.1 - 0.19 11.5 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA thioesterase Hist_deacetyl PF00850.19 CCU97398.1 - 4.1e-41 141.4 0.2 5.7e-41 141.0 0.2 1.2 1 0 0 1 1 1 1 Histone deacetylase domain BppL_N PF18338.1 CCU97398.1 - 0.2 11.5 0.1 0.9 9.4 0.1 2.1 2 0 0 2 2 2 0 Lower baseplate protein N-terminal domain RRM_1 PF00076.22 CCU97400.1 - 1.3e-09 37.7 0.0 2.7e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCU97400.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S19e PF01090.19 CCU97401.1 - 2.1e-47 160.3 0.0 2.3e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RNA_pol_3_Rpc31 PF11705.8 CCU97401.1 - 0.0071 16.6 5.3 0.0073 16.6 5.3 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Dicty_REP PF05086.12 CCU97401.1 - 0.25 9.3 7.9 0.27 9.2 7.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC45 PF02724.14 CCU97401.1 - 1.2 7.3 5.0 1.2 7.4 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CCU97401.1 - 2 6.4 11.5 2 6.4 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 CCU97401.1 - 2.9 7.6 6.1 4.1 7.1 6.1 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 CCU97401.1 - 6.3 6.0 13.3 7.4 5.8 13.3 1.1 1 0 0 1 1 1 0 NOA36 protein HR1 PF02185.16 CCU97402.1 - 5.5e-18 64.9 13.3 1e-11 44.8 0.7 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 CCU97402.1 - 1.5e-12 47.2 14.0 1.3e-10 40.9 7.4 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 CCU97402.1 - 0.00032 20.9 0.0 0.00056 20.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF4349 PF14257.6 CCU97402.1 - 0.019 14.4 0.3 0.066 12.7 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) AAA_11 PF13086.6 CCU97403.1 - 1.5e-69 234.7 0.5 2.2e-69 234.1 0.5 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 CCU97403.1 - 2.4e-57 193.8 0.0 3.6e-57 193.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.7 CCU97403.1 - 3.5e-28 98.3 0.4 4.8e-28 97.8 0.4 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_30 PF13604.6 CCU97403.1 - 1.1e-11 44.8 1.6 8e-08 32.2 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CCU97403.1 - 2.3e-10 41.0 0.0 7.7e-10 39.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CCU97403.1 - 8.7e-08 32.2 0.1 0.067 12.9 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CCU97403.1 - 0.00016 22.0 0.1 0.00098 19.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 CCU97403.1 - 0.00031 20.4 0.0 0.0029 17.2 0.0 2.0 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 CCU97403.1 - 0.0071 16.2 0.1 0.37 10.6 0.0 2.5 2 0 0 2 2 2 1 Helicase Glyoxalase_4 PF13669.6 CCU97403.1 - 0.011 16.0 0.0 5.6 7.3 0.0 2.8 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DEAD PF00270.29 CCU97403.1 - 0.02 14.7 0.1 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase Adeno_IVa2 PF02456.15 CCU97403.1 - 0.051 12.4 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA PF00004.29 CCU97403.1 - 0.056 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 CCU97403.1 - 0.056 13.3 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain FtsK_SpoIIIE PF01580.18 CCU97403.1 - 0.059 12.7 0.0 0.2 11.0 0.0 1.9 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_6 PF12774.7 CCU97403.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Aldedh PF00171.22 CCU97403.1 - 0.23 10.0 1.3 0.36 9.3 1.3 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family APG6_N PF17675.1 CCU97403.1 - 0.3 11.6 4.4 0.69 10.5 4.4 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_16 PF13191.6 CCU97403.1 - 6.9 7.0 11.5 2 8.7 5.4 3.4 2 1 1 3 3 3 0 AAA ATPase domain CPSF_A PF03178.15 CCU97404.1 - 4e-31 108.5 0.0 1.1e-30 107.0 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region Porin_3 PF01459.22 CCU97406.1 - 5.8e-67 226.0 0.7 6.5e-67 225.8 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin Endosulfine PF04667.17 CCU97407.1 - 2.1e-27 95.1 0.2 3.8e-27 94.2 0.2 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region HLH PF00010.26 CCU97408.1 - 1.1e-17 63.7 1.7 1.3e-17 63.4 0.8 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Helicase_C PF00271.31 CCU97409.1 - 3.6e-12 46.6 0.1 7.8e-11 42.3 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CCU97409.1 - 3.7e-09 37.2 1.3 7.5e-09 36.2 0.5 2.0 2 0 0 2 2 2 1 RecQ zinc-binding DEAD PF00270.29 CCU97409.1 - 2.9e-07 30.4 0.0 4.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.10 CCU97409.1 - 0.001 18.8 0.0 0.0032 17.2 0.0 1.9 1 1 0 1 1 1 1 RQC domain AbrB_C PF18277.1 CCU97409.1 - 0.012 15.2 0.1 5.5 6.7 0.0 3.1 3 0 0 3 3 3 0 AbrB C-terminal domain AAA_22 PF13401.6 CCU97409.1 - 0.026 14.8 0.2 0.35 11.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain Peptidase_M22 PF00814.25 CCU97410.1 - 1.5e-19 70.8 0.0 1.6e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family tRNA-synt_2b PF00587.25 CCU97411.1 - 3.1e-28 98.9 0.0 7.9e-28 97.6 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CCU97411.1 - 4.1e-06 26.8 0.0 8.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain DUF1656 PF07869.12 CCU97411.1 - 0.1 12.6 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) zf-H2C2_5 PF13909.6 CCU97411.1 - 0.47 10.3 2.2 0.85 9.4 2.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain RmlD_sub_bind PF04321.17 CCU97412.1 - 3e-05 23.3 0.0 0.00072 18.7 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CCU97412.1 - 0.0005 19.3 0.0 0.034 13.3 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein Epimerase PF01370.21 CCU97412.1 - 0.0022 17.5 0.0 0.19 11.1 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CCU97412.1 - 0.0045 16.9 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CCU97412.1 - 0.13 11.3 0.0 1.6 7.7 0.0 2.2 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CCU97413.1 - 9.6e-05 22.0 0.1 0.00016 21.2 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CCU97413.1 - 0.00015 21.0 0.1 0.0002 20.6 0.1 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 CCU97413.1 - 0.00017 21.2 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CCU97413.1 - 0.0039 17.1 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CCU97413.1 - 0.015 14.8 0.0 0.053 13.0 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 CCU97413.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CCU97413.1 - 0.016 14.2 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_transf_21 PF13506.6 CCU97413.1 - 0.072 12.6 0.0 0.095 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 21 WD40 PF00400.32 CCU97414.1 - 2.2e-09 37.8 3.8 0.0022 18.8 0.0 4.6 5 1 0 5 5 5 3 WD domain, G-beta repeat DUF1681 PF07933.14 CCU97415.1 - 2.4e-52 176.6 0.0 2.7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CcmD PF04995.14 CCU97416.1 - 0.087 12.9 0.9 0.2 11.8 0.9 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) POP1 PF06978.11 CCU97417.1 - 4.1e-32 111.8 20.2 5.6e-17 62.4 15.7 2.3 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 CCU97417.1 - 2.9e-21 75.6 0.0 7.2e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T_C PF08669.11 CCU97417.1 - 0.1 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain DLH PF01738.18 CCU97418.1 - 0.085 12.4 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF4774 PF15999.5 CCU97418.1 - 0.15 11.9 4.7 0.34 10.8 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) Plasmodium_HRP PF05403.11 CCU97420.1 - 6.7e-08 32.6 16.4 6.7e-08 32.6 16.4 1.9 2 0 0 2 2 2 1 Plasmodium histidine-rich protein (HRPII/III) Tyr-DNA_phospho PF06087.12 CCU97421.1 - 1.9e-45 155.6 0.0 2.5e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase TFA2_Winged_2 PF18121.1 CCU97421.1 - 1e-14 53.9 0.0 2.3e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 CCU97421.1 - 3.7e-08 33.5 0.1 6.4e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 TFIIE beta subunit core domain PLDc_2 PF13091.6 CCU97421.1 - 9e-06 25.6 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain Pkinase PF00069.25 CCU97422.1 - 2.6e-62 210.6 0.0 3.6e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97422.1 - 1.2e-25 90.3 0.0 1.7e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCU97422.1 - 0.023 13.7 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FUSC PF04632.12 CCU97424.1 - 0.42 9.1 12.1 0.54 8.7 12.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CK_II_beta PF01214.18 CCU97425.1 - 2.2e-53 180.8 0.0 2.5e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Na_H_Exchanger PF00999.21 CCU97426.1 - 1.3e-34 119.6 0.7 8.3e-24 84.1 4.5 2.0 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 CCU97427.1 - 1.8e-11 43.5 2.9 8.2e-11 41.3 2.9 1.8 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Tom22 PF04281.13 CCU97428.1 - 5.4e-39 133.1 0.6 6.1e-39 133.0 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Cir_N PF10197.9 CCU97428.1 - 0.066 13.4 2.2 0.43 10.8 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR DNA_pol_phi PF04931.13 CCU97428.1 - 9.8 4.1 8.2 11 3.9 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Fcf2 PF08698.11 CCU97430.1 - 9.5e-13 48.4 0.0 2.7e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Dcc1 PF09724.9 CCU97430.1 - 0.14 11.4 1.4 0.19 11.0 1.4 1.1 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 CDC45 PF02724.14 CCU97430.1 - 0.6 8.3 7.6 0.68 8.2 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Sas10 PF09368.10 CCU97431.1 - 1.1e-27 96.3 4.6 2.8e-27 95.0 4.6 1.8 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CCU97431.1 - 0.34 11.6 0.1 0.34 11.6 0.1 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Chisel PF15355.6 CCU97431.1 - 2.3 8.5 5.8 3 8.1 1.3 2.9 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel WD40 PF00400.32 CCU97432.1 - 2e-11 44.3 10.5 0.0023 18.7 0.2 6.3 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU97432.1 - 5.6e-08 33.0 0.0 0.0003 21.0 0.0 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain COX8 PF02285.15 CCU97432.1 - 0.12 12.3 0.1 0.33 10.8 0.1 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII Pho88 PF10032.9 CCU97433.1 - 7.1e-72 240.5 0.1 8.3e-72 240.3 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Cullin PF00888.22 CCU97434.1 - 8.7e-171 569.6 1.1 1.1e-170 569.3 1.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CCU97434.1 - 1.4e-23 82.7 0.7 4.6e-23 81.0 0.7 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF3877 PF12993.7 CCU97434.1 - 0.08 12.8 0.2 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) VWA PF00092.28 CCU97435.1 - 0.0043 17.3 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain RRM_1 PF00076.22 CCU97436.1 - 1e-40 137.4 0.0 1.2e-16 60.2 0.0 4.7 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CCU97436.1 - 1.6e-09 37.6 0.0 0.19 11.8 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CCU97436.1 - 1.1e-05 25.5 0.0 0.46 10.7 0.0 4.6 4 0 0 4 4 4 1 RNA recognition motif RRM_occluded PF16842.5 CCU97436.1 - 0.0014 18.4 0.0 5.7 6.9 0.0 4.4 4 0 0 4 4 4 1 Occluded RNA-recognition motif Suf PF05843.14 CCU97436.1 - 1.1 9.2 3.8 0.7 9.8 0.9 1.9 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) DUF2373 PF10180.9 CCU97437.1 - 3e-13 49.4 1.4 6.8e-09 35.4 2.1 2.4 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) LZ_Tnp_IS66 PF13007.7 CCU97437.1 - 6.2 7.7 7.3 1.2 10.0 2.4 2.4 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain HA2 PF04408.23 CCU97438.1 - 2.7e-14 53.3 0.1 6.4e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCU97438.1 - 1.9e-09 37.8 0.0 5.6e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CCU97438.1 - 1.5e-08 34.9 0.0 3.9e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 CCU97438.1 - 8.6e-07 29.3 0.1 5.2e-06 26.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 CCU97438.1 - 1.8e-06 27.8 0.0 6e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CCU97438.1 - 0.0012 18.9 0.2 0.012 15.7 0.2 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCU97438.1 - 0.0055 16.4 2.1 0.015 15.1 0.3 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CCU97438.1 - 0.0071 16.7 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CCU97438.1 - 0.021 14.2 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 CCU97438.1 - 0.044 14.2 2.5 0.093 13.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain T2SSE PF00437.20 CCU97438.1 - 0.054 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 CCU97438.1 - 0.074 12.5 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 CCU97438.1 - 0.089 12.4 0.0 0.69 9.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CCU97438.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CCU97438.1 - 0.11 13.0 0.0 0.36 11.3 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_29 PF13555.6 CCU97438.1 - 0.12 12.1 0.1 0.34 10.7 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain HECT PF00632.25 CCU97439.1 - 7.6e-27 94.6 0.0 2.1e-20 73.4 0.0 2.2 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) DUF3295 PF11702.8 CCU97439.1 - 4.8e-05 22.9 2.8 4.8e-05 22.9 2.8 3.3 2 2 1 3 3 3 1 Protein of unknown function (DUF3295) CDC45 PF02724.14 CCU97439.1 - 1 7.6 7.5 1.3 7.2 6.0 1.8 2 0 0 2 2 2 0 CDC45-like protein SURF2 PF05477.11 CCU97439.1 - 1.7 8.3 6.6 3.4 7.3 6.6 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) IQ PF00612.27 CCU97439.1 - 2.1 8.3 6.1 0.17 11.8 0.8 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif RR_TM4-6 PF06459.12 CCU97439.1 - 7 6.4 8.0 16 5.2 8.0 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ras PF00071.22 CCU97440.1 - 2.8e-31 108.3 0.0 2.9e-21 75.7 0.0 2.1 2 0 0 2 2 2 2 Ras family EF_assoc_2 PF08356.12 CCU97440.1 - 7e-31 106.1 0.1 2e-30 104.6 0.0 1.9 2 0 0 2 2 1 1 EF hand associated EF_assoc_1 PF08355.12 CCU97440.1 - 1.5e-29 101.4 0.4 6.9e-29 99.3 0.0 2.1 2 0 0 2 2 2 1 EF hand associated Roc PF08477.13 CCU97440.1 - 1.7e-15 57.3 0.0 1.7e-09 38.0 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 CCU97440.1 - 6.2e-10 38.2 0.7 0.00015 21.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CCU97440.1 - 3.1e-09 35.7 0.3 0.002 17.5 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CCU97440.1 - 5.3e-08 32.0 0.3 0.0041 16.6 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CCU97440.1 - 2.4e-07 31.1 0.0 0.005 17.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair MMR_HSR1 PF01926.23 CCU97440.1 - 4.4e-07 30.0 0.0 0.019 15.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCU97440.1 - 2e-05 24.5 0.2 0.86 9.5 0.0 3.7 2 2 2 4 4 4 1 RsgA GTPase AAA_16 PF13191.6 CCU97440.1 - 5.2e-05 23.7 0.0 0.081 13.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CCU97440.1 - 0.00016 22.0 0.0 0.5 10.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CCU97440.1 - 0.00099 18.9 0.0 0.063 13.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 CCU97440.1 - 0.0014 18.7 0.0 0.88 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) cobW PF02492.19 CCU97440.1 - 0.0019 17.8 0.1 4.1 7.0 0.0 3.8 2 2 2 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CCU97440.1 - 0.0039 17.7 0.0 0.99 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain SPARC_Ca_bdg PF10591.9 CCU97440.1 - 0.0048 17.2 0.3 2.5 8.4 0.0 3.3 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region ABC_tran PF00005.27 CCU97440.1 - 0.0054 17.2 0.0 1.5 9.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter EF-hand_10 PF14788.6 CCU97440.1 - 0.0061 16.4 0.5 0.49 10.3 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CCU97440.1 - 0.0072 16.1 2.4 2.2 8.2 0.2 2.8 3 0 0 3 3 2 1 EF-hand domain pair NACHT PF05729.12 CCU97440.1 - 0.0084 16.0 0.0 0.53 10.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 CCU97440.1 - 0.013 15.9 0.0 8.5 6.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CCU97440.1 - 0.037 14.2 0.0 0.34 11.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CCU97440.1 - 0.037 13.8 0.0 2.4 7.9 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ploopntkinase3 PF18751.1 CCU97440.1 - 0.052 13.5 0.0 4.2 7.2 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 CCU97440.1 - 0.057 13.7 0.0 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 CCU97440.1 - 0.069 12.7 0.0 12 5.4 0.0 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 CCU97440.1 - 0.073 12.8 0.2 14 5.3 0.0 3.2 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CCU97440.1 - 0.088 12.1 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 CCU97440.1 - 0.1 12.2 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CCU97440.1 - 0.1 11.9 0.1 0.51 9.7 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.18 CCU97440.1 - 0.12 11.7 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.23 CCU97440.1 - 0.12 12.5 0.0 0.87 9.6 0.0 2.3 2 1 0 2 2 2 0 Dynamin family MCM PF00493.23 CCU97440.1 - 0.13 11.4 0.0 3.2 6.8 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain DUF2075 PF09848.9 CCU97440.1 - 0.15 11.2 0.0 0.73 9.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Guanylate_kin PF00625.21 CCU97440.1 - 0.16 11.7 0.0 6.1 6.5 0.0 2.6 2 1 1 3 3 3 0 Guanylate kinase RNA_helicase PF00910.22 CCU97440.1 - 0.16 12.3 0.0 34 4.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AIG1 PF04548.16 CCU97440.1 - 0.26 10.6 0.1 0.92 8.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family Sulfate_transp PF00916.20 CCU97441.1 - 5e-19 68.3 13.3 5e-19 68.3 13.3 1.6 2 0 0 2 2 2 1 Sulfate permease family Peptidase_C48 PF02902.19 CCU97442.1 - 4.5e-08 33.2 0.0 6.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ldh_1_C PF02866.18 CCU97443.1 - 1.6e-46 158.3 0.0 5.7e-46 156.5 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CCU97443.1 - 2.6e-29 102.1 1.4 4.5e-27 94.9 0.0 2.3 1 1 1 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Malic_M PF03949.15 CCU97444.1 - 1.7e-87 293.0 0.0 2.1e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CCU97444.1 - 3e-66 222.7 0.0 5.5e-66 221.8 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Shikimate_DH PF01488.20 CCU97444.1 - 0.1 12.6 0.9 0.6 10.2 0.1 2.4 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase DEAD PF00270.29 CCU97445.1 - 4.5e-23 81.9 0.0 7e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU97445.1 - 2.6e-14 53.5 0.0 7.8e-13 48.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 CCU97445.1 - 3.5e-05 24.5 0.0 0.00012 22.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.11 CCU97445.1 - 0.00058 20.2 0.2 0.0022 18.3 0.2 1.9 2 0 0 2 2 2 1 DNA replication factor CDT1 like Suc_Fer-like PF06999.12 CCU97445.1 - 0.07 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Sucrase/ferredoxin-like PRP1_N PF06424.12 CCU97446.1 - 5.7e-51 172.8 6.5 5.7e-51 172.8 6.5 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CCU97446.1 - 3.3e-20 71.0 49.2 0.00026 21.6 0.6 14.1 8 4 6 14 14 13 7 Tetratricopeptide repeat TPR_19 PF14559.6 CCU97446.1 - 2.8e-14 53.4 20.8 0.0029 18.1 1.5 9.2 7 2 3 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 CCU97446.1 - 1.4e-07 31.0 2.6 0.046 13.9 0.1 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 CCU97446.1 - 9.6e-05 22.5 15.8 0.013 15.7 4.3 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat Suf PF05843.14 CCU97446.1 - 0.00017 21.7 0.4 1.3 8.9 0.0 4.2 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_12 PF13424.6 CCU97446.1 - 0.00024 21.3 18.7 0.05 13.9 2.7 6.7 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 CCU97446.1 - 0.00095 19.7 6.2 36 5.3 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCU97446.1 - 0.0027 17.5 0.1 0.17 11.8 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CCU97446.1 - 0.03 14.7 0.0 13 6.4 0.1 4.7 5 0 0 5 5 3 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 CCU97446.1 - 0.052 13.5 3.0 2.3 8.1 0.1 3.8 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF3808 PF10300.9 CCU97446.1 - 0.074 11.8 0.2 0.24 10.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) Mitoc_mL59 PF18126.1 CCU97446.1 - 0.91 9.8 6.3 0.97 9.7 0.3 2.7 2 1 0 2 2 2 0 Mitochondrial ribosomal protein mL59 TPR_16 PF13432.6 CCU97446.1 - 3.6 8.3 33.9 1.2 9.8 3.4 7.5 7 1 0 8 8 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 CCU97446.1 - 8.7 6.0 22.0 1.5 8.5 4.4 4.7 4 2 2 6 6 6 0 Tetratricopeptide repeat-like domain HSF_DNA-bind PF00447.17 CCU97447.1 - 1.2e-17 64.2 0.0 2.6e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding SCO1-SenC PF02630.14 CCU97448.1 - 1.3e-45 154.6 0.0 4.2e-45 152.9 0.0 1.7 2 0 0 2 2 2 1 SCO1/SenC Tcf25 PF04910.14 CCU97449.1 - 4.1e-90 302.4 0.0 5.1e-90 302.1 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Ferrochelatase PF00762.19 CCU97450.1 - 4.3e-107 357.9 0.0 4.9e-107 357.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 CCU97450.1 - 0.11 12.8 0.0 3.4 8.1 0.0 2.5 2 0 0 2 2 2 0 CbiX Xpo1 PF08389.12 CCU97451.1 - 9.9e-10 38.7 0.0 2e-08 34.4 0.0 3.2 4 0 0 4 4 4 1 Exportin 1-like protein HEAT_EZ PF13513.6 CCU97451.1 - 8.2 7.1 9.7 4.5 7.9 0.3 4.6 5 0 0 5 5 5 0 HEAT-like repeat F-actin_cap_A PF01267.17 CCU97452.1 - 7.9e-78 261.5 0.0 9e-78 261.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit F_actin_cap_B PF01115.17 CCU97452.1 - 0.021 14.4 0.0 0.06 13.0 0.0 1.8 1 1 0 1 1 1 0 F-actin capping protein, beta subunit Pet127 PF08634.10 CCU97453.1 - 6.9e-85 284.8 0.1 9.3e-85 284.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Ribosomal_L6e PF01159.19 CCU97454.1 - 1.9e-38 131.4 0.1 3.3e-38 130.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 CCU97454.1 - 0.0024 18.1 0.2 0.0024 18.1 0.2 2.5 4 0 0 4 4 4 1 Ribosomal protein L6, N-terminal domain Mur_ligase_M PF08245.12 CCU97455.1 - 0.00028 21.0 0.0 0.0054 16.7 0.0 2.8 1 1 1 2 2 2 1 Mur ligase middle domain Tam41_Mmp37 PF09139.11 CCU97456.1 - 1.1e-104 350.4 0.0 1.4e-104 350.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Ysc84 PF04366.12 CCU97458.1 - 3.4e-38 130.3 0.3 5.8e-38 129.5 0.3 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Calcipressin PF04847.12 CCU97459.1 - 1.1e-23 84.0 2.2 4.3e-23 82.0 0.2 2.6 2 1 0 2 2 2 1 Calcipressin Voldacs PF03517.13 CCU97459.1 - 1.5e-15 57.5 6.0 5.5e-15 55.7 6.0 2.0 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Ribosomal_L36e PF01158.18 CCU97460.1 - 7.4e-32 109.5 2.3 1.1e-20 73.6 0.0 2.0 2 0 0 2 2 2 2 Ribosomal protein L36e eIF3_N PF09440.10 CCU97461.1 - 1.6e-34 119.2 3.9 3.6e-34 118.1 3.9 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 CCU97461.1 - 0.00036 21.0 0.4 0.0012 19.3 0.1 2.1 2 0 0 2 2 2 1 PCI domain TPR_MLP1_2 PF07926.12 CCU97461.1 - 0.026 14.6 1.7 0.068 13.2 1.7 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ANAPC3 PF12895.7 CCU97461.1 - 0.38 11.0 3.1 5.6 7.3 0.4 3.0 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Methyltransf_28 PF02636.17 CCU97462.1 - 2.7e-66 223.9 0.0 3.5e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF4232 PF14016.6 CCU97462.1 - 0.0059 16.7 1.7 0.2 11.8 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4232) RNA_pol_I_A49 PF06870.12 CCU97463.1 - 1.3e-97 327.2 0.0 1.5e-97 326.9 0.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor HTH_6 PF01418.17 CCU97463.1 - 0.022 14.7 0.2 0.88 9.6 0.1 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family Arf PF00025.21 CCU97464.1 - 1.1e-79 265.9 0.1 1.3e-79 265.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCU97464.1 - 2.7e-14 53.4 0.0 3.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CCU97464.1 - 8e-14 51.5 0.0 9.9e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CCU97464.1 - 4.9e-13 49.0 0.9 4.3e-09 36.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CCU97464.1 - 1e-12 48.0 0.0 1.1e-12 47.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CCU97464.1 - 1.1e-10 41.3 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCU97464.1 - 3.9e-06 26.9 0.0 6.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CCU97464.1 - 0.0059 15.9 0.3 0.022 14.0 0.1 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase DUF3292 PF11696.8 CCU97465.1 - 8.8e-13 47.5 10.3 6.3e-06 24.9 0.9 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF3292) PRT_C PF08372.10 CCU97465.1 - 1e-05 25.3 3.3 1.4e-05 24.9 0.6 2.4 1 1 1 2 2 2 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 CCU97465.1 - 0.0028 17.6 3.6 0.081 12.9 1.3 2.2 2 0 0 2 2 2 2 Reticulon DUF639 PF04842.12 CCU97465.1 - 0.045 13.2 1.7 0.97 8.8 0.1 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) GMC_oxred_N PF00732.19 CCU97466.1 - 4e-45 154.5 0.0 6.9e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CCU97466.1 - 1.2e-34 119.9 0.2 2.3e-34 119.0 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CCU97466.1 - 9.4e-06 24.9 0.1 1.6e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CCU97466.1 - 2e-05 24.4 2.9 0.0012 18.6 0.3 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CCU97466.1 - 3.7e-05 23.0 8.2 0.005 16.0 2.0 2.8 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 CCU97466.1 - 6.9e-05 23.0 0.4 0.00027 21.1 0.4 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CCU97466.1 - 0.00015 21.2 0.1 0.00074 18.9 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CCU97466.1 - 0.00028 20.2 0.0 0.0015 17.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCU97466.1 - 0.01 16.4 0.2 0.022 15.3 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCU97466.1 - 0.015 14.6 0.1 0.046 13.0 0.1 1.8 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 CCU97466.1 - 0.026 13.8 0.1 5 6.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 CCU97466.1 - 0.065 13.5 0.1 0.18 12.1 0.0 1.8 2 0 0 2 2 1 0 TrkA-N domain HI0933_like PF03486.14 CCU97466.1 - 0.12 11.1 0.2 0.19 10.4 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein AIRC PF00731.20 CCU97467.1 - 4.1e-62 208.1 2.3 1e-61 206.8 2.3 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 CCU97467.1 - 7.6e-53 178.6 0.0 1.1e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 CCU97467.1 - 1.9e-19 69.0 0.0 3.7e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 CCU97467.1 - 0.0036 16.9 0.0 0.02 14.5 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 CCU97467.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Propionate catabolism activator CoA_binding_2 PF13380.6 CCU97467.1 - 0.26 11.8 1.5 20 5.7 0.0 3.4 2 1 1 3 3 3 0 CoA binding domain LRR_6 PF13516.6 CCU97468.1 - 5.3e-09 35.4 0.6 0.0032 17.4 0.0 4.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 CCU97468.1 - 0.055 14.0 0.0 1.3e+02 3.8 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat DFRP_C PF16543.5 CCU97469.1 - 1.8e-30 105.2 0.9 1.8e-30 105.2 0.9 3.5 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf_CCCH_4 PF18345.1 CCU97469.1 - 1.7e-05 24.7 6.9 1.7e-05 24.7 6.9 3.4 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH PF00642.24 CCU97469.1 - 5.8e-05 22.9 1.5 5.8e-05 22.9 1.5 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CCU97469.1 - 0.0018 18.0 11.9 0.019 14.8 2.9 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 CCU97469.1 - 0.0077 16.9 19.1 0.019 15.7 7.2 3.7 2 1 1 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 CCU97469.1 - 0.011 16.2 12.6 0.19 12.3 4.6 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CCU97469.1 - 0.023 14.9 1.3 0.023 14.9 1.3 3.0 2 1 0 3 3 3 0 Zinc-finger containing family Sec6 PF06046.13 CCU97470.1 - 1.1e-116 390.5 0.1 2e-116 389.7 0.0 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF1073 PF06381.11 CCU97470.1 - 0.027 13.3 0.1 0.72 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1073) DUF4061 PF13270.6 CCU97470.1 - 2.2 8.6 4.9 2.9 8.3 0.2 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4061) Syntaxin-6_N PF09177.11 CCU97470.1 - 4 8.1 5.1 1.2e+02 3.3 0.3 4.0 4 0 0 4 4 4 0 Syntaxin 6, N-terminal GDA1_CD39 PF01150.17 CCU97471.1 - 2.2e-94 316.6 0.0 3.5e-94 315.9 0.0 1.3 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CCU97471.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.5 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Gemini_mov PF01708.16 CCU97471.1 - 0.13 12.1 1.8 0.28 11.0 0.6 2.2 2 0 0 2 2 2 0 Geminivirus putative movement protein LapA_dom PF06305.11 CCU97471.1 - 0.28 11.0 1.2 0.64 9.9 1.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4381 PF14316.6 CCU97471.1 - 0.85 9.8 4.8 2.2 8.5 4.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Ras PF00071.22 CCU97472.1 - 6.1e-31 107.2 0.0 7.5e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 CCU97472.1 - 0.0018 17.7 0.0 0.0021 17.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCU97472.1 - 0.002 18.3 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CCU97472.1 - 0.014 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase FeoB_N PF02421.18 CCU97472.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 CCU97472.1 - 0.044 13.8 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 CCU97472.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain HSP70 PF00012.20 CCU97473.1 - 7.2e-262 869.9 14.4 8.1e-262 869.7 14.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCU97473.1 - 2e-19 69.6 0.5 4.6e-17 61.8 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 CCU97473.1 - 0.00022 20.6 2.5 0.057 12.7 0.1 3.1 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase FGGY_C PF02782.16 CCU97473.1 - 0.0054 16.5 0.0 0.027 14.2 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FIVAR PF07554.13 CCU97473.1 - 0.014 16.2 3.8 0.032 15.0 1.4 2.8 3 0 0 3 3 3 0 FIVAR domain FtsA PF14450.6 CCU97473.1 - 0.044 14.2 4.5 4.6 7.7 0.0 3.4 3 1 0 3 3 3 0 Cell division protein FtsA CP12 PF02672.15 CCU97473.1 - 1.1 10.1 9.9 0.48 11.2 3.0 2.7 2 0 0 2 2 2 0 CP12 domain TRAF_BIRC3_bd PF16673.5 CCU97473.1 - 4.2 7.2 6.9 6 6.7 1.0 3.4 4 0 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain UBN_AB PF14075.6 CCU97474.1 - 1.3e-35 123.1 0.8 2.1e-35 122.4 0.8 1.2 1 0 0 1 1 1 1 Ubinuclein conserved middle domain HUN PF08729.10 CCU97474.1 - 4.3e-11 42.6 0.1 9.6e-11 41.5 0.1 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Mito_fiss_reg PF05308.11 CCU97474.1 - 2.9 7.9 8.7 5.8 6.9 8.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DAO PF01266.24 CCU97475.1 - 2.1e-39 136.1 0.0 3.1e-39 135.6 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 CCU97475.1 - 1.1e-08 34.7 0.2 0.0007 18.8 0.5 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CCU97475.1 - 1.5e-08 34.2 4.7 2.1e-07 30.4 4.7 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CCU97475.1 - 2.3e-07 30.3 0.0 0.00034 19.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CCU97475.1 - 6e-07 29.6 0.1 3e-05 24.2 0.1 3.1 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CCU97475.1 - 9.2e-05 21.8 0.1 0.00018 20.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CCU97475.1 - 0.00014 22.4 0.4 0.00034 21.1 0.2 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCU97475.1 - 0.00037 19.9 0.0 0.0024 17.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CCU97475.1 - 0.00053 18.8 0.4 0.0048 15.7 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein TrkA_N PF02254.18 CCU97475.1 - 0.00064 20.0 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 CCU97475.1 - 0.0016 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CCU97475.1 - 0.002 17.5 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 CCU97475.1 - 0.005 16.8 0.5 2.6 8.0 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 CCU97475.1 - 0.0052 17.2 0.0 0.0098 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 CCU97475.1 - 0.0077 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 CCU97475.1 - 0.01 15.2 0.1 0.032 13.6 0.1 1.7 2 0 0 2 2 2 0 ThiF family ApbA PF02558.16 CCU97475.1 - 0.012 15.2 0.2 0.024 14.3 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 CCU97475.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 CCU97475.1 - 0.027 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 CCU97475.1 - 0.051 12.8 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 CCU97475.1 - 0.14 11.4 0.3 2.3 7.4 0.0 2.3 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Epimerase PF01370.21 CCU97475.1 - 0.17 11.3 0.2 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Acyl-CoA_dh_1 PF00441.24 CCU97476.1 - 3.2e-29 102.1 0.5 5.1e-29 101.4 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 CCU97476.1 - 4.7e-18 65.1 0.0 1.1e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 CCU97476.1 - 6.9e-17 62.1 0.0 2e-16 60.6 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CCU97476.1 - 6.1e-16 58.4 0.1 1.1e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CCU97476.1 - 1.5e-05 25.3 0.0 2.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Clat_adaptor_s PF01217.20 CCU97477.1 - 2e-42 144.5 0.8 1.3e-31 109.5 0.9 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Arf PF00025.21 CCU97477.1 - 2.7e-23 82.3 0.1 6.4e-14 51.8 0.2 2.5 1 1 1 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 CCU97477.1 - 0.0051 16.0 0.0 0.0083 15.3 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit DPBB_1 PF03330.18 CCU97478.1 - 0.0005 20.3 0.1 0.0011 19.2 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase MF_alpha_N PF05436.11 CCU97478.1 - 0.15 12.0 0.1 0.22 11.5 0.1 1.2 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus HhH-GPD PF00730.25 CCU97479.1 - 2.1e-19 70.0 0.0 6.2e-19 68.5 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 CCU97479.1 - 8.9e-15 54.6 0.0 1.9e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 CCU97479.1 - 0.0015 18.3 0.5 0.0048 16.7 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif Whib PF02467.16 CCU97479.1 - 3.8 8.2 6.1 1.5 9.5 1.5 2.4 2 0 0 2 2 2 0 Transcription factor WhiB EndIII_4Fe-2S PF10576.9 CCU97479.1 - 4.3 7.8 14.9 0.11 12.9 7.2 2.5 3 0 0 3 3 3 0 Iron-sulfur binding domain of endonuclease III TPR_2 PF07719.17 CCU97480.1 - 6.1e-35 116.5 21.2 0.00014 21.7 0.1 11.2 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 CCU97480.1 - 3e-26 90.1 11.0 0.00096 18.9 0.0 10.1 11 0 0 11 11 10 5 Tetratricopeptide repeat ANAPC3 PF12895.7 CCU97480.1 - 3e-18 65.8 16.8 1.1e-07 32.0 0.7 6.5 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CCU97480.1 - 7.5e-18 63.2 1.1 0.0064 16.6 0.0 8.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 CCU97480.1 - 3.5e-13 50.0 58.2 2.8e-10 40.7 1.5 8.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 CCU97480.1 - 3e-12 46.6 40.7 6.7e-08 32.7 1.2 8.6 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CCU97480.1 - 8.6e-12 45.4 33.0 0.011 16.2 1.8 8.7 4 2 6 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 CCU97480.1 - 2.5e-11 43.1 6.0 0.0088 15.7 0.1 7.1 6 1 2 8 8 8 3 TPR repeat TPR_7 PF13176.6 CCU97480.1 - 6.4e-10 38.4 17.3 0.0022 17.9 0.1 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CCU97480.1 - 3.7e-07 30.4 54.2 0.051 14.4 0.7 10.4 8 3 3 11 11 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 CCU97480.1 - 3.1e-06 27.2 14.0 1.2 9.6 0.0 8.9 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.6 CCU97480.1 - 0.00013 22.3 28.9 0.16 12.7 0.1 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 CCU97480.1 - 0.00022 21.0 27.2 0.11 12.4 0.3 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 CCU97480.1 - 0.002 18.2 34.5 0.036 14.2 1.2 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat PPR PF01535.20 CCU97480.1 - 0.054 13.8 1.7 31 5.1 0.0 4.2 6 0 0 6 6 3 0 PPR repeat DUF3856 PF12968.7 CCU97480.1 - 0.56 10.3 4.9 13 5.8 0.0 4.3 4 1 0 5 5 5 0 Domain of Unknown Function (DUF3856) Fes1 PF08609.10 CCU97481.1 - 6e-25 87.9 0.7 1.5e-24 86.6 0.2 2.0 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.23 CCU97481.1 - 8.1e-05 22.5 2.3 0.17 12.0 0.3 3.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 CCU97481.1 - 0.11 11.1 0.1 1.5 7.3 0.0 2.0 1 1 1 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.6 CCU97481.1 - 0.11 13.1 5.5 0.23 12.0 0.5 3.6 3 1 1 4 4 4 0 HEAT-like repeat HEAT PF02985.22 CCU97481.1 - 0.67 10.4 2.8 67 4.2 0.0 4.0 5 0 0 5 5 5 0 HEAT repeat FAM165 PF14981.6 CCU97482.1 - 0.18 11.6 0.7 0.26 11.1 0.7 1.2 1 0 0 1 1 1 0 FAM165 family Pkinase PF00069.25 CCU97483.1 - 9.8e-34 116.9 0.0 7.1e-22 78.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97483.1 - 4.3e-19 68.8 0.0 3.2e-18 66.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU97483.1 - 0.0027 17.1 0.1 0.16 11.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.11 CCU97483.1 - 0.23 10.5 0.0 0.35 9.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Cullin PF00888.22 CCU97484.1 - 1.7e-183 611.7 0.0 2.4e-183 611.1 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CCU97484.1 - 7e-28 96.5 0.1 1.5e-27 95.4 0.1 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain GGDEF_2 PF17853.1 CCU97484.1 - 1.9 8.8 6.4 1.4 9.2 0.9 3.4 3 0 0 3 3 3 0 GGDEF-like domain Forkhead PF00250.18 CCU97485.1 - 4.4e-31 107.0 0.0 7.5e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FXR_C1 PF16096.5 CCU97485.1 - 1.3 9.2 7.4 0.14 12.4 0.7 2.9 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Aminotran_3 PF00202.21 CCU97486.1 - 1.3e-109 366.6 0.0 1.6e-109 366.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CCU97486.1 - 0.0012 18.1 0.0 0.0027 16.9 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II CPSase_L_D2 PF02786.17 CCU97487.1 - 2.7e-79 265.6 0.0 4.8e-79 264.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CCU97487.1 - 6.7e-65 218.6 0.0 1e-64 217.9 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CCU97487.1 - 4.9e-40 136.5 0.2 1.2e-39 135.2 0.2 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CCU97487.1 - 3.4e-28 97.9 0.0 9.3e-28 96.5 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CCU97487.1 - 8.3e-26 91.1 0.0 1.7e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 CCU97487.1 - 2.3e-14 53.0 1.3 8.5e-14 51.2 1.1 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CCU97487.1 - 4.2e-08 33.0 0.0 8.3e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 CCU97487.1 - 1.1e-07 31.6 1.6 9e-05 22.2 0.3 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 CCU97487.1 - 2e-05 24.2 0.0 4.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 CCU97487.1 - 0.00061 19.1 0.1 0.0045 16.2 0.1 2.1 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CCU97487.1 - 0.0015 19.3 0.2 0.14 12.9 0.2 2.6 1 1 1 2 2 2 1 HlyD family secretion protein ATP-grasp_3 PF02655.14 CCU97487.1 - 0.0021 18.1 0.0 0.0076 16.3 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CCU97487.1 - 0.0039 16.8 0.0 0.66 9.6 0.0 2.7 3 0 0 3 3 3 1 RimK-like ATP-grasp domain GARS_A PF01071.19 CCU97487.1 - 0.0094 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.6 CCU97487.1 - 0.024 14.2 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain NQRA PF05896.11 CCU97487.1 - 0.031 13.7 0.5 0.061 12.8 0.5 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATPgrasp_ST PF14397.6 CCU97487.1 - 0.071 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 CCU97487.1 - 0.11 12.4 0.1 1.4 8.9 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 CCU97487.1 - 0.13 12.1 0.3 0.52 10.2 0.3 2.0 1 0 0 1 1 1 0 Glycine cleavage H-protein Ribosomal_S13 PF00416.22 CCU97488.1 - 3.2e-52 176.3 2.0 3.7e-52 176.1 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CCU97488.1 - 0.0027 16.6 0.0 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 CCU97488.1 - 0.013 15.8 0.3 0.045 14.0 0.1 2.0 1 1 1 2 2 2 0 Helix-hairpin-helix motif DUF1822 PF08852.11 CCU97488.1 - 0.031 13.3 0.0 0.039 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Mito_carr PF00153.27 CCU97489.1 - 4.8e-66 218.7 3.0 9.9e-22 76.7 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 CCU97490.1 - 0.003 17.9 0.2 0.065 13.6 0.0 2.8 3 0 0 3 3 3 1 Tim17/Tim22/Tim23/Pmp24 family eIF3g PF12353.8 CCU97491.1 - 1e-40 139.0 1.3 1.6e-40 138.4 1.3 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CCU97491.1 - 1.8e-18 66.1 0.0 2.9e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCU97491.1 - 0.0085 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif vATP-synt_E PF01991.18 CCU97492.1 - 7.3e-53 178.9 13.1 9.5e-53 178.6 13.1 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF935 PF06074.12 CCU97492.1 - 0.63 8.7 8.0 0.24 10.1 5.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF935) Ribosomal_L37 PF08561.10 CCU97493.1 - 7.2e-30 104.0 3.7 1.2e-29 103.3 3.7 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Nitr_red_assoc PF09655.10 CCU97493.1 - 0.026 15.2 1.3 0.038 14.6 1.3 1.5 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) RabGAP-TBC PF00566.18 CCU97494.1 - 1.7e-47 161.8 0.0 2.7e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CPSF73-100_C PF11718.8 CCU97495.1 - 7.9e-57 192.3 0.0 1.1e-56 191.9 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CCU97495.1 - 2.2e-30 105.2 0.0 4.1e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 CCU97495.1 - 1.1e-16 60.6 0.1 2.2e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 CCU97495.1 - 3.2e-14 52.8 0.0 1.8e-13 50.4 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 CCU97495.1 - 0.006 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 CCU97495.1 - 0.14 12.1 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain MCM PF00493.23 CCU97496.1 - 1.8e-99 331.4 0.0 2.8e-99 330.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCU97496.1 - 4e-38 130.1 0.7 6.9e-38 129.3 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCU97496.1 - 1.8e-27 95.5 3.6 3.9e-27 94.5 3.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCU97496.1 - 1e-14 55.0 0.2 4.2e-14 53.0 0.1 2.2 2 0 0 2 2 1 1 MCM N-terminal domain AAA_5 PF07728.14 CCU97496.1 - 4e-08 33.3 0.1 1.9e-07 31.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CCU97496.1 - 3.1e-07 30.0 0.0 7.6e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CCU97496.1 - 3.5e-05 23.7 0.0 0.00075 19.4 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCU97496.1 - 0.0018 18.0 0.1 2.5 7.8 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 CCU97496.1 - 0.0055 17.1 3.1 0.35 11.2 3.1 3.4 1 1 0 1 1 1 1 AAA ATPase domain GntR PF00392.21 CCU97496.1 - 0.087 12.5 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family AAA PF00004.29 CCU97496.1 - 0.13 12.7 0.0 0.42 11.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GGA_N-GAT PF18308.1 CCU97496.1 - 0.13 11.9 0.1 0.43 10.2 0.1 1.8 1 0 0 1 1 1 0 GGA N-GAT domain HORMA PF02301.18 CCU97497.1 - 1.6e-27 96.5 0.0 1.8e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 CCU97497.1 - 0.00013 21.9 0.1 0.00022 21.2 0.1 1.4 1 0 0 1 1 1 1 Autophagy-related protein 101 bacHORMA_2 PF18173.1 CCU97497.1 - 0.0047 16.8 0.2 0.018 14.9 0.1 2.1 2 1 0 2 2 2 1 Bacterial HORMA domain 2 Y_phosphatase2 PF03162.13 CCU97498.1 - 8.7e-59 197.8 0.0 1.1e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CCU97498.1 - 4.1e-07 30.2 0.0 5.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CCU97498.1 - 0.00096 18.8 0.0 0.0014 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CCU97498.1 - 0.002 17.9 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ATP-synt_G PF04718.15 CCU97499.1 - 1.5e-12 48.2 0.7 3.9e-12 46.9 0.7 1.7 1 1 0 1 1 1 1 Mitochondrial ATP synthase g subunit Misat_Tub_SegII PF10644.9 CCU97501.1 - 1.1e-17 64.4 0.0 1.9e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CCU97501.1 - 5.1e-17 62.1 0.0 1.5e-16 60.6 0.0 1.8 1 1 0 1 1 1 1 Tubulin domain Pterin_4a PF01329.19 CCU97501.1 - 5.8e-16 58.5 1.2 8.4e-16 57.9 0.0 1.9 2 0 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase DUF2781 PF10914.8 CCU97501.1 - 1.7e-08 35.0 0.7 5.4e-08 33.4 0.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) Tubulin PF00091.25 CCU97501.1 - 0.00072 19.8 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Vps16_C PF04840.12 CCU97502.1 - 3.6e-45 154.4 0.0 9.4e-26 90.6 0.0 2.1 2 0 0 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.13 CCU97502.1 - 7.7e-41 140.2 0.0 1.4e-23 83.3 0.0 2.2 2 0 0 2 2 2 2 Vps16, N-terminal region GCS PF03074.16 CCU97503.1 - 4.8e-128 427.6 0.0 6.9e-128 427.1 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 CCU97503.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) UCH PF00443.29 CCU97504.1 - 0.00062 19.3 0.0 0.00062 19.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UMP1 PF05348.11 CCU97505.1 - 4.6e-35 120.4 2.6 5.5e-35 120.1 2.6 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 rRNA_proc-arch PF13234.6 CCU97506.1 - 3.3e-78 263.3 0.0 5.3e-78 262.7 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 CCU97506.1 - 1.9e-53 180.5 0.8 3.9e-53 179.5 0.8 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CCU97506.1 - 1.6e-18 67.1 0.0 4.2e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU97506.1 - 4.9e-07 30.1 0.0 2.4e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU97506.1 - 0.00087 19.3 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HAMP PF00672.25 CCU97506.1 - 0.021 15.2 1.4 6.1 7.3 0.2 3.0 2 0 0 2 2 2 0 HAMP domain ATPase PF06745.13 CCU97506.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 CCU97506.1 - 1.8 8.9 0.0 1.8 8.9 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain NMD3 PF04981.13 CCU97507.1 - 6.6e-82 274.6 4.0 8.9e-82 274.2 4.0 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 CCU97507.1 - 0.0053 16.8 4.8 1.4 9.0 5.9 2.8 1 1 0 1 1 1 1 Double zinc ribbon HEPN_Apea PF18739.1 CCU97507.1 - 0.13 12.7 0.2 5.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Apea-like HEPN NinF PF05810.12 CCU97507.1 - 0.15 11.9 1.8 0.5 10.3 0.3 2.5 2 1 1 3 3 3 0 NinF protein TFIIE_alpha PF02002.17 CCU97508.1 - 3.4e-12 46.2 0.1 6e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit Bul1_N PF04425.12 CCU97508.1 - 0.071 11.9 1.4 0.1 11.3 1.4 1.2 1 0 0 1 1 1 0 Bul1 N terminus TF_Zn_Ribbon PF08271.12 CCU97508.1 - 0.11 12.1 0.8 0.24 10.9 0.8 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding MFS_1 PF07690.16 CCU97509.1 - 4.5e-19 68.6 34.5 9.8e-18 64.2 13.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2370 PF10176.9 CCU97509.1 - 0.26 10.9 2.0 0.59 9.7 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) ThiF PF00899.21 CCU97510.1 - 2e-72 243.4 0.1 2.8e-72 243.0 0.1 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 CCU97510.1 - 5.2e-12 46.2 2.2 2.2e-08 34.3 0.1 2.4 1 1 0 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 CCU97510.1 - 1.5e-10 41.5 0.3 3.5e-10 40.3 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Pyr_redox PF00070.27 CCU97510.1 - 0.037 14.6 0.8 0.53 10.9 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CCU97510.1 - 0.055 13.9 0.5 0.38 11.2 0.1 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 CCU97510.1 - 0.082 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.23 CCU97510.1 - 0.11 12.5 0.4 7.5 6.6 0.1 2.5 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain PAPA-1 PF04795.12 CCU97511.1 - 3.8e-27 94.9 2.7 3.8e-27 94.9 2.7 2.8 2 1 1 3 3 3 1 PAPA-1-like conserved region Polysacc_deac_2 PF04748.13 CCU97511.1 - 0.021 14.0 0.2 0.036 13.2 0.2 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase HA2 PF04408.23 CCU97512.1 - 8.1e-23 80.8 0.1 8.1e-23 80.8 0.1 2.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CCU97512.1 - 7.5e-13 48.7 0.0 3.3e-12 46.6 0.0 2.1 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CCU97512.1 - 8.9e-13 48.6 0.0 2.4e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 CCU97512.1 - 6.2e-11 42.5 1.0 1.3e-10 41.5 1.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 CCU97512.1 - 0.00024 21.4 0.0 0.00093 19.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CCU97512.1 - 0.00029 20.7 0.1 0.00063 19.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 CCU97512.1 - 0.00046 19.3 0.0 0.0012 17.9 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 CCU97512.1 - 0.0005 19.8 0.1 0.0012 18.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCU97512.1 - 0.0046 17.3 0.1 0.0093 16.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CCU97512.1 - 0.0078 16.7 0.1 0.26 11.8 0.1 2.5 1 1 0 1 1 1 1 ABC transporter DUF2075 PF09848.9 CCU97512.1 - 0.052 12.8 1.1 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 CCU97512.1 - 0.088 12.4 0.4 0.4 10.3 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain GATA PF00320.27 CCU97513.1 - 0.0056 16.3 7.3 0.016 14.8 0.2 2.6 2 0 0 2 2 2 2 GATA zinc finger Sel1 PF08238.12 CCU97514.1 - 2.9e-43 145.3 12.9 5.2e-05 23.8 0.1 7.1 7 0 0 7 7 7 7 Sel1 repeat EF-hand_1 PF00036.32 CCU97515.1 - 4.6e-36 119.7 10.8 1.6e-10 39.8 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CCU97515.1 - 2.1e-33 113.9 7.3 4.6e-16 58.4 0.4 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 CCU97515.1 - 3.5e-33 113.9 2.5 1.9e-19 69.9 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCU97515.1 - 1.6e-26 89.9 4.8 5.6e-09 35.2 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CCU97515.1 - 1.4e-24 84.4 7.3 5.8e-07 28.7 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CCU97515.1 - 2.9e-14 53.1 0.3 9.9e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CCU97515.1 - 2.7e-09 36.9 0.3 0.00014 21.7 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CCU97515.1 - 1e-07 32.2 0.0 0.002 18.5 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 CCU97515.1 - 1.9e-06 27.8 2.6 0.036 14.1 0.0 3.5 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CCU97515.1 - 9.1e-05 22.5 0.5 0.00018 21.6 0.2 1.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CCU97515.1 - 0.0002 21.5 3.3 0.24 11.6 1.9 3.0 1 1 1 2 2 2 2 Dockerin type I domain DUF1103 PF06513.11 CCU97515.1 - 0.00028 20.6 1.3 0.00032 20.4 1.3 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.13 CCU97515.1 - 0.00058 19.8 0.2 0.79 9.7 0.1 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF5580 PF17743.1 CCU97515.1 - 0.0033 16.0 0.0 0.0035 15.9 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_11 PF08976.11 CCU97515.1 - 0.0034 18.2 0.0 0.077 13.9 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain RNA_pol_Rpb4 PF03874.16 CCU97515.1 - 0.0048 17.2 1.1 1.2 9.5 0.1 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb4 dCache_2 PF08269.11 CCU97515.1 - 0.014 14.6 0.1 0.11 11.7 0.1 2.0 1 1 1 2 2 2 0 Cache domain SurA_N_2 PF13623.6 CCU97515.1 - 0.045 13.6 0.8 0.95 9.3 0.2 2.1 1 1 1 2 2 2 0 SurA N-terminal domain Poly_export PF02563.16 CCU97515.1 - 0.048 13.9 0.1 0.66 10.2 0.0 2.6 2 2 1 3 3 3 0 Polysaccharide biosynthesis/export protein SapB_1 PF05184.15 CCU97515.1 - 0.066 13.3 0.4 26 4.9 0.0 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 MotA_activ PF09114.10 CCU97515.1 - 0.11 12.7 0.1 0.3 11.3 0.0 1.8 1 1 0 1 1 1 0 Transcription factor MotA, activation domain RuvA_C PF07499.13 CCU97515.1 - 0.11 13.0 0.1 4.6 7.8 0.1 2.8 3 0 0 3 3 3 0 RuvA, C-terminal domain DUF327 PF03885.13 CCU97515.1 - 0.18 11.8 2.1 11 6.0 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF327) GTSE1_N PF15259.6 CCU97516.1 - 0.0025 18.0 1.0 0.0025 18.0 1.0 2.0 2 0 0 2 2 2 1 G-2 and S-phase expressed 1 Maf1 PF09174.10 CCU97517.1 - 8.1e-38 130.3 0.0 2.1e-31 109.4 0.0 2.2 2 0 0 2 2 2 2 Maf1 regulator Peptidase_S10 PF00450.22 CCU97518.1 - 4.2e-91 306.4 0.0 5.8e-91 306.0 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Histidinol_dh PF00815.20 CCU97519.1 - 2.6e-162 540.5 1.1 3.8e-162 540.0 1.1 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 CCU97519.1 - 1.4e-23 82.5 0.4 2.6e-23 81.6 0.4 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 CCU97519.1 - 6.6e-13 48.9 0.3 2.2e-12 47.3 0.1 2.0 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 CCU97519.1 - 0.027 14.6 0.1 0.05 13.8 0.1 1.4 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain UPF0047 PF01894.17 CCU97520.1 - 8e-39 132.4 0.0 9.1e-39 132.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Carn_acyltransf PF00755.20 CCU97521.1 - 2.6e-165 551.4 0.0 3e-165 551.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Pkinase PF00069.25 CCU97522.1 - 1.2e-57 195.3 0.0 1.4e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97522.1 - 6.1e-29 101.1 0.0 1.1e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU97522.1 - 4e-06 26.4 0.0 1.2e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CCU97522.1 - 0.00014 21.8 4.8 0.13 12.1 0.5 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 CCU97522.1 - 0.0008 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CCU97522.1 - 0.0033 16.3 0.0 0.0046 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase MKT1_C PF12246.8 CCU97523.1 - 5.3e-75 251.8 0.0 1.2e-74 250.6 0.0 1.6 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CCU97523.1 - 4.6e-24 84.6 0.0 1.1e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 CCU97523.1 - 7.5e-05 23.1 0.0 0.00017 22.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain SARA PF11409.8 CCU97523.1 - 0.2 11.9 0.0 0.51 10.6 0.0 1.7 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) Ribosomal_L5_C PF00673.21 CCU97524.1 - 2.8e-23 81.9 0.0 5.2e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CCU97524.1 - 5.2e-18 65.1 0.3 2.1e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 PDZ_5 PF17817.1 CCU97525.1 - 0.055 13.8 0.3 0.15 12.4 0.3 1.7 1 0 0 1 1 1 0 PDZ domain DEAD PF00270.29 CCU97526.1 - 5.2e-46 156.6 0.0 1.5e-45 155.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU97526.1 - 6.8e-30 103.7 0.0 1.4e-29 102.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU97526.1 - 0.16 12.0 0.0 0.3 11.0 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit IU_nuc_hydro PF01156.19 CCU97527.1 - 6.3e-46 157.3 0.0 9.6e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CN_hydrolase PF00795.22 CCU97527.1 - 0.0067 15.8 0.4 0.0096 15.3 0.4 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LSM PF01423.22 CCU97528.1 - 1.4e-18 66.3 1.4 4.7e-18 64.6 1.4 1.7 1 1 0 1 1 1 1 LSM domain Pox_Ag35 PF03286.14 CCU97528.1 - 0.028 14.2 0.2 0.04 13.7 0.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ROF PF07073.12 CCU97528.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) Aminotran_1_2 PF00155.21 CCU97529.1 - 1.7e-26 93.2 0.0 2.2e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CCU97529.1 - 8.9e-07 28.0 0.0 1.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Sec1 PF00995.23 CCU97530.1 - 2.2e-82 278.1 0.0 3e-82 277.7 0.0 1.1 1 0 0 1 1 1 1 Sec1 family MotY_N PF18393.1 CCU97530.1 - 0.18 11.9 0.9 1.7 8.8 0.0 2.7 3 0 0 3 3 3 0 MotY N-terminal domain PAT1 PF09770.9 CCU97531.1 - 6.6e-92 309.2 34.3 1.3e-77 261.9 15.6 3.6 1 1 0 2 2 2 2 Topoisomerase II-associated protein PAT1 PTCB-BRCT PF12738.7 CCU97532.1 - 6.7e-29 99.6 1.1 2.6e-15 56.1 0.0 4.6 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 CCU97532.1 - 2.9e-26 91.6 0.0 6.1e-10 39.3 0.0 5.2 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CCU97532.1 - 3e-17 62.8 0.0 2.8e-07 30.8 0.0 5.1 5 0 0 5 5 5 3 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CCU97532.1 - 5.1e-15 55.2 0.0 4e-10 39.5 0.0 4.1 4 0 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 CCU97532.1 - 1.8e-06 28.2 3.5 0.14 12.5 0.0 4.0 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain Sulfate_transp PF00916.20 CCU97533.1 - 5.2e-111 371.1 17.0 6.7e-111 370.7 17.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CCU97533.1 - 2.8e-09 36.6 0.0 1.4e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 CCU97533.1 - 0.0013 19.1 0.1 0.0032 17.8 0.1 1.7 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CCU97533.1 - 0.017 15.5 2.0 0.017 15.5 2.0 3.1 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily SNN_transmemb PF09049.10 CCU97533.1 - 0.019 14.9 1.8 0.12 12.3 1.8 2.5 1 0 0 1 1 1 0 Stannin transmembrane CNH PF00780.22 CCU97534.1 - 8.9e-38 130.5 0.0 1.3e-37 130.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 CCU97534.1 - 1.3e-21 77.7 0.0 2.3e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain CDP-OH_P_transf PF01066.21 CCU97535.1 - 5.2e-18 65.6 0.1 5.2e-18 65.6 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cnd2 PF05786.14 CCU97536.1 - 3.5e-146 489.0 12.0 4.3e-141 472.1 12.0 3.9 1 1 0 1 1 1 1 Condensin complex subunit 2 DUF416 PF04222.12 CCU97536.1 - 0.047 13.1 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF416) DAGAT PF03982.13 CCU97537.1 - 3.8e-73 246.0 0.1 5.7e-73 245.4 0.1 1.3 1 1 0 1 1 1 1 Diacylglycerol acyltransferase PLA2_B PF01735.18 CCU97539.1 - 1.9e-143 478.5 0.3 2.2e-143 478.2 0.3 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 CCU97539.1 - 0.03 14.5 0.2 0.094 12.9 0.1 1.9 2 0 0 2 2 2 0 Patatin-like phospholipase IBR PF01485.21 CCU97539.1 - 0.14 12.4 1.2 0.31 11.3 1.2 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain GTP_EFTU PF00009.27 CCU97540.1 - 1.8e-47 161.4 0.0 2.7e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 CCU97540.1 - 2.1e-37 127.6 0.1 3.7e-37 126.7 0.1 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CCU97540.1 - 5.5e-16 58.4 0.0 1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCU97540.1 - 2.6e-07 30.9 0.1 4.8e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CCU97540.1 - 9.7e-06 25.6 0.0 1.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CCU97540.1 - 2e-05 24.7 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 CCU97540.1 - 3.5e-05 23.6 0.0 6.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 CCU97540.1 - 0.013 14.9 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RST PF12174.8 CCU97540.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain RsgA_GTPase PF03193.16 CCU97540.1 - 0.12 12.3 0.0 0.74 9.7 0.0 2.2 1 1 1 2 2 2 0 RsgA GTPase WD40 PF00400.32 CCU97541.1 - 5.5e-17 61.8 2.5 0.00052 20.8 0.6 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU97541.1 - 1.9e-06 28.1 0.0 3.6e-05 24.0 0.1 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 CCU97541.1 - 0.017 15.1 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CCU97541.1 - 0.017 14.1 0.5 0.063 12.2 0.0 2.2 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MMS1_N PF10433.9 CCU97541.1 - 0.025 13.2 0.0 0.072 11.7 0.0 1.6 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Aminotran_1_2 PF00155.21 CCU97543.1 - 2.2e-47 162.0 0.0 2.8e-46 158.4 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CCU97543.1 - 0.0018 17.7 0.0 0.0024 17.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 CCU97543.1 - 0.022 13.5 0.0 0.046 12.4 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aldedh PF00171.22 CCU97544.1 - 2e-121 405.8 0.0 5.2e-121 404.4 0.0 1.6 2 0 0 2 2 2 1 Aldehyde dehydrogenase family JAB PF01398.21 CCU97545.1 - 1.5e-28 99.1 0.0 2.5e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CCU97545.1 - 3e-06 27.0 0.0 7.2e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CSN5_C PF18323.1 CCU97545.1 - 0.053 14.4 0.1 0.1 13.5 0.1 1.5 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Cyclin_N PF00134.23 CCU97546.1 - 4.7e-43 146.0 0.3 3.6e-41 139.9 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCU97546.1 - 2.2e-31 108.4 0.1 3.9e-31 107.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Yippee-Mis18 PF03226.14 CCU97547.1 - 3.9e-25 88.1 0.0 5.7e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AT_hook PF02178.19 CCU97547.1 - 0.0042 16.8 9.3 0.032 14.1 2.7 3.1 2 0 0 2 2 2 2 AT hook motif RIG-I_C-RD PF11648.8 CCU97547.1 - 0.062 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I Phlebovirus_G1 PF07243.11 CCU97547.1 - 0.3 9.4 1.3 0.43 8.9 1.3 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 DCP1 PF06058.13 CCU97548.1 - 3.7e-32 110.7 0.0 5e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family TIMELESS PF04821.14 CCU97549.1 - 5.7e-77 258.7 0.0 8.3e-77 258.2 0.0 1.2 1 0 0 1 1 1 1 Timeless protein DEAD PF00270.29 CCU97550.1 - 3.8e-34 118.0 0.2 1.7e-33 115.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU97550.1 - 5.6e-29 100.7 0.2 1.2e-28 99.7 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 CCU97550.1 - 0.0029 17.3 0.1 0.0084 15.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain SPA PF08616.10 CCU97551.1 - 5.6e-06 26.3 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 CCU97551.1 - 0.00055 18.7 0.0 0.0026 16.5 0.0 1.9 1 1 0 1 1 1 1 Transport protein Avl9 DENN PF02141.21 CCU97551.1 - 0.0017 18.4 0.0 0.025 14.6 0.0 2.3 1 1 0 1 1 1 1 DENN (AEX-3) domain CRAL_TRIO PF00650.20 CCU97552.1 - 5e-23 81.6 0.0 8e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CCU97552.1 - 0.0045 17.1 0.0 0.0092 16.1 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCU97552.1 - 0.068 13.4 0.9 0.26 11.5 0.1 2.4 2 1 1 3 3 3 0 CRAL/TRIO, N-terminal domain Ribosomal_L32e PF01655.18 CCU97553.1 - 3.3e-40 136.9 2.1 1.7e-39 134.5 2.1 2.0 1 1 0 1 1 1 1 Ribosomal protein L32 DUF3301 PF11743.8 CCU97553.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Ribosomal_L13 PF00572.18 CCU97554.1 - 1.6e-11 44.6 0.1 4.6e-10 39.8 0.1 2.2 1 1 0 1 1 1 1 Ribosomal protein L13 Alpha-2-MRAP_C PF06401.11 CCU97554.1 - 0.078 12.9 0.3 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Mg_trans_NIPA PF05653.14 CCU97555.1 - 0.012 14.7 2.3 0.37 9.8 0.2 2.1 2 0 0 2 2 2 0 Magnesium transporter NIPA HemY_N PF07219.13 CCU97555.1 - 0.35 11.1 1.3 5.5 7.2 0.7 2.5 2 0 0 2 2 2 0 HemY protein N-terminus HABP4_PAI-RBP1 PF04774.15 CCU97556.1 - 1.4e-06 29.1 13.3 1.4e-06 29.1 13.3 2.8 1 1 1 2 2 2 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 CCU97556.1 - 0.0001 23.1 12.9 0.0001 23.1 12.9 4.9 3 2 0 3 3 3 1 Stm1 Ribosomal_S3_C PF00189.20 CCU97557.1 - 9.6e-24 83.7 0.3 2e-23 82.7 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CCU97557.1 - 5.4e-10 39.0 0.0 1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 KH domain Dynamin_N PF00350.23 CCU97558.1 - 2.7e-40 138.2 0.0 6.1e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 CCU97558.1 - 7e-06 25.5 0.5 4.3e-05 22.9 0.0 2.4 3 0 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.23 CCU97558.1 - 8.9e-05 22.5 0.0 0.0003 20.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Fib_alpha PF08702.10 CCU97558.1 - 0.13 12.5 0.2 0.65 10.2 0.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Roc PF08477.13 CCU97558.1 - 0.18 12.0 0.0 0.51 10.6 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RNase_T PF00929.24 CCU97559.1 - 0.00018 22.1 0.0 0.00039 21.0 0.0 1.6 1 0 0 1 1 1 1 Exonuclease CHORD PF04968.12 CCU97559.1 - 0.13 13.0 0.2 0.34 11.7 0.2 1.7 1 1 0 1 1 1 0 CHORD PP2C PF00481.21 CCU97560.1 - 3.7e-31 108.7 0.0 3.4e-20 72.8 0.0 3.2 3 0 0 3 3 3 3 Protein phosphatase 2C CSN8_PSD8_EIF3K PF10075.9 CCU97560.1 - 1.6e-23 83.3 0.0 2.7e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CCU97560.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family AAA PF00004.29 CCU97561.1 - 1.1e-51 174.7 0.0 4.2e-39 134.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 CCU97561.1 - 1.3e-09 37.7 0.6 3.9e-08 33.0 0.1 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 CCU97561.1 - 4.6e-09 36.7 0.0 0.00013 22.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 CCU97561.1 - 6.9e-09 35.4 0.0 1.4e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CCU97561.1 - 6.9e-09 36.3 0.0 0.0072 16.7 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 CCU97561.1 - 1.6e-08 34.9 0.0 1.5e-05 25.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CCU97561.1 - 1.6e-07 30.9 0.0 0.015 14.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 CCU97561.1 - 5.1e-07 29.8 0.2 0.0016 18.5 0.1 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CCU97561.1 - 1.1e-06 28.5 0.2 0.016 15.0 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CCU97561.1 - 2e-06 27.7 0.1 0.017 14.9 0.0 2.6 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CCU97561.1 - 7.7e-06 25.4 0.4 0.0054 16.1 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CCU97561.1 - 8.8e-06 26.3 0.0 0.021 15.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CCU97561.1 - 1.1e-05 25.4 1.6 0.019 14.9 0.0 3.4 4 0 0 4 4 4 2 NACHT domain AAA_30 PF13604.6 CCU97561.1 - 1.7e-05 24.6 0.1 0.24 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CCU97561.1 - 1.9e-05 25.0 0.0 0.059 13.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 CCU97561.1 - 3.4e-05 24.0 0.0 0.16 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CCU97561.1 - 3.8e-05 23.7 0.0 0.088 12.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 CCU97561.1 - 4e-05 23.4 0.0 0.059 13.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein PhoH PF02562.16 CCU97561.1 - 5.6e-05 22.7 0.0 0.078 12.4 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activat PF00158.26 CCU97561.1 - 0.00013 21.7 0.1 0.69 9.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 CCU97561.1 - 0.00019 21.5 0.0 0.89 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 CCU97561.1 - 0.00019 20.8 0.2 0.0064 15.9 0.1 2.5 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 CCU97561.1 - 0.00022 20.8 1.4 0.028 13.9 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region Parvo_NS1 PF01057.17 CCU97561.1 - 0.00041 19.5 0.1 0.81 8.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 CCU97561.1 - 0.00052 19.3 0.1 0.52 9.4 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.27 CCU97561.1 - 0.00053 20.5 0.3 0.4 11.2 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 CCU97561.1 - 0.0011 18.6 0.3 1.4 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CCU97561.1 - 0.0011 18.9 0.2 9.8 6.0 0.0 3.7 2 2 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 CCU97561.1 - 0.0023 17.8 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CCU97561.1 - 0.0043 17.4 0.3 0.95 9.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 CCU97561.1 - 0.0061 16.8 0.0 0.56 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CCU97561.1 - 0.0076 16.3 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 CCU97561.1 - 0.0097 15.8 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CCU97561.1 - 0.012 14.9 0.1 3 7.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 CCU97561.1 - 0.031 14.0 0.1 2.6 7.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain CDC48_N PF02359.18 CCU97561.1 - 0.044 14.0 0.0 0.16 12.2 0.0 2.0 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain T2SSE PF00437.20 CCU97561.1 - 0.051 12.6 0.0 6.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 CCU97561.1 - 0.056 13.2 0.1 4 7.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase DAP3 PF10236.9 CCU97561.1 - 0.084 12.0 0.2 8.4 5.5 0.0 2.5 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 VID27 PF08553.10 CCU97562.1 - 1.5e-154 514.4 0.0 2.1e-154 513.9 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 CCU97562.1 - 1.1e-36 126.3 0.1 1.1e-36 126.3 0.1 2.0 2 1 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 CCU97562.1 - 3.1e-30 104.7 5.0 9.7e-30 103.1 2.2 2.6 2 0 0 2 2 2 1 VID27 PH-like domain eIF-3_zeta PF05091.12 CCU97563.1 - 8.5e-192 638.7 0.0 9.7e-192 638.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) P53_C PF11619.8 CCU97564.1 - 0.089 12.9 0.8 0.23 11.6 0.8 1.7 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain Arg_decarbox_C PF17944.1 CCU97564.1 - 0.14 12.8 1.5 5.1 7.7 0.1 2.7 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Stealth_CR3 PF17102.5 CCU97564.1 - 1.4 8.9 4.5 0.41 10.6 1.3 1.8 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 APH PF01636.23 CCU97565.1 - 5.3e-10 39.6 0.4 5.9e-06 26.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CCU97565.1 - 8.7e-09 35.0 0.0 5.7e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CCU97565.1 - 2.8e-08 33.5 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 CCU97565.1 - 4.8e-08 32.8 0.0 1.2e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 CCU97565.1 - 0.00047 19.5 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.20 CCU97565.1 - 0.0087 15.4 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 CCU97565.1 - 0.027 14.0 0.0 0.067 12.8 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 CCU97566.1 - 1.3e-28 100.1 0.0 1.1e-15 57.8 0.0 3.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97566.1 - 1.3e-06 27.9 0.0 0.00085 18.7 0.0 3.3 2 1 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 CCU97566.1 - 0.042 13.5 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Creatinase_N_2 PF16189.5 CCU97568.1 - 6.1e-45 153.2 0.0 3.3e-44 150.8 0.0 2.0 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CCU97568.1 - 1.4e-42 145.7 0.0 2.5e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 CCU97568.1 - 5.9e-17 62.6 0.1 9.2e-13 49.0 0.0 2.6 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CCU97568.1 - 2.7e-15 56.2 0.4 2.7e-15 56.2 0.4 3.2 3 0 0 3 3 3 1 C-terminal region of peptidase_M24 fn3_2 PF16893.5 CCU97570.1 - 2.9e-30 104.3 1.1 5.1e-30 103.5 0.5 1.6 2 0 0 2 2 2 1 Fibronectin type III domain CHS5_N PF16892.5 CCU97570.1 - 8e-16 57.7 0.1 1.5e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 CCU97570.1 - 1.4e-05 25.3 0.0 2.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.21 CCU97570.1 - 6.8e-05 23.1 0.2 0.00015 22.0 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III domain PTCB-BRCT PF12738.7 CCU97570.1 - 0.00064 19.6 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.8 CCU97570.1 - 0.00083 19.5 0.1 0.0028 17.8 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 CCU97570.1 - 0.026 14.9 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain RhoGEF PF00621.20 CCU97571.1 - 2.9e-15 57.0 0.4 2.9e-15 57.0 0.4 1.6 2 0 0 2 2 2 1 RhoGEF domain CCDC92 PF14916.6 CCU97571.1 - 0.64 9.8 3.2 9.7 6.1 0.3 2.7 2 0 0 2 2 2 0 Coiled-coil domain of unknown function TSC22 PF01166.18 CCU97571.1 - 1.7 9.0 4.7 38 4.7 0.1 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family Ysc84 PF04366.12 CCU97572.1 - 9.2e-32 109.5 0.0 1.3e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator YdjC PF04794.12 CCU97572.1 - 0.18 11.8 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 YdjC-like protein NECFESHC PF16621.5 CCU97572.1 - 1.2 9.2 2.9 0.74 9.8 0.9 1.7 2 0 0 2 2 2 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 ERCC4 PF02732.15 CCU97573.1 - 1.9e-20 73.6 0.0 3.7e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Peptidase_M17 PF00883.21 CCU97574.1 - 1.8e-115 385.5 0.1 2.3e-115 385.2 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CCU97574.1 - 2.3e-06 27.5 0.1 4.6e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DAO PF01266.24 CCU97575.1 - 1.9e-59 202.0 0.5 2.2e-59 201.8 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CCU97575.1 - 2.5e-08 33.4 0.7 1.5e-06 27.6 0.7 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CCU97575.1 - 5.1e-08 33.4 0.2 0.0001 22.8 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CCU97575.1 - 1.6e-05 25.1 0.2 4.1e-05 23.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CCU97575.1 - 1.9e-05 24.0 0.1 0.0016 17.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCU97575.1 - 0.0012 18.1 0.1 0.0023 17.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 CCU97575.1 - 0.0081 15.1 0.3 1.2 8.0 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Mqo PF06039.15 CCU97575.1 - 0.0085 14.7 0.1 0.32 9.5 0.0 2.2 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.18 CCU97575.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 CCU97575.1 - 0.028 13.7 0.2 0.26 10.5 0.2 2.0 1 1 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 CCU97575.1 - 0.031 14.3 0.2 6.4 6.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CCU97575.1 - 0.035 13.2 0.1 0.061 12.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 CCU97575.1 - 0.046 14.0 0.6 0.26 11.5 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 CCU97575.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.19 CCU97575.1 - 0.062 12.7 0.1 1.7 7.9 0.0 2.5 2 1 0 2 2 2 0 GMC oxidoreductase HI0933_like PF03486.14 CCU97575.1 - 0.1 11.3 0.2 0.77 8.4 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein RRM_1 PF00076.22 CCU97576.1 - 6.9e-10 38.6 0.0 1.5e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rota_VP2 PF05087.12 CCU97576.1 - 0.36 8.9 8.7 0.037 12.2 3.6 1.7 2 0 0 2 2 2 0 Rotavirus VP2 protein RSN1_7TM PF02714.15 CCU97578.1 - 1.6e-38 132.6 14.4 4.6e-38 131.1 14.4 1.7 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CCU97578.1 - 1.7e-09 38.2 0.0 2.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Virul_fac_BrkB PF03631.15 CCU97578.1 - 0.003 17.2 5.9 0.0061 16.2 4.0 2.0 1 1 1 2 2 2 1 Virulence factor BrkB Glyco_hydro_47 PF01532.20 CCU97581.1 - 4.6e-86 289.5 0.0 5.5e-86 289.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.20 CCU97582.1 - 2.3e-46 158.7 0.0 2.7e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CedA PF10729.9 CCU97582.1 - 0.0076 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Cell division activator CedA Glyco_transf_20 PF00982.21 CCU97583.1 - 1.5e-132 442.7 5.1 3e-131 438.4 5.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CCU97583.1 - 3.3e-67 226.0 0.0 6e-67 225.2 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Dor1 PF04124.12 CCU97584.1 - 6.8e-06 25.0 0.3 1.5e-05 23.8 0.2 1.7 2 0 0 2 2 2 1 Dor1-like family TetR_C_35 PF18556.1 CCU97584.1 - 0.34 11.1 6.1 0.66 10.1 1.6 3.2 2 1 0 2 2 2 0 Bacterial Tetracyclin repressor, C-terminal domain SMC_N PF02463.19 CCU97585.1 - 4.7e-31 107.9 1.5 6.6e-31 107.5 1.5 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCU97585.1 - 1.9e-08 34.6 0.0 1.2e-07 32.1 0.0 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain SbcCD_C PF13558.6 CCU97585.1 - 0.033 14.4 0.8 0.37 11.0 0.1 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 CCU97585.1 - 0.04 13.7 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3533 PF12051.8 CCU97586.1 - 1.4e-69 234.9 7.6 1.7e-69 234.6 7.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Lipase_3 PF01764.25 CCU97587.1 - 1.2e-17 64.1 0.0 1.7e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S10 PF00450.22 CCU97588.1 - 8.3e-79 265.9 0.0 9.7e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Sel1 PF08238.12 CCU97589.1 - 1e-36 124.6 19.4 3.6e-06 27.5 0.1 8.0 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 CCU97589.1 - 0.11 13.2 0.9 1.1 10.1 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat SPESP1 PF15754.5 CCU97589.1 - 7.3 5.7 5.2 13 4.9 5.2 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Exo_endo_phos PF03372.23 CCU97591.1 - 1.9e-22 80.0 0.7 1.5e-21 77.0 0.7 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 CCU97591.1 - 2.5e-11 43.6 3.3 2.9e-05 24.4 0.4 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCU97591.1 - 2.4e-08 33.6 4.1 3.5e-05 23.5 0.8 2.5 1 1 1 2 2 2 2 Leucine rich repeat Y_phosphatase PF00102.27 CCU97591.1 - 0.007 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_1 PF00560.33 CCU97591.1 - 0.032 14.7 1.9 1.3e+02 3.8 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat HSP90 PF00183.18 CCU97592.1 - 1.3e-228 760.1 27.8 1.6e-228 759.8 27.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CCU97592.1 - 1.1e-14 54.9 0.1 2.1e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CCU97592.1 - 7.4e-11 42.0 0.1 2.3e-10 40.4 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 CCU97592.1 - 0.063 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN Peptidase_C37 PF05416.12 CCU97592.1 - 2.8 6.4 10.4 0.18 10.3 0.4 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Bystin PF05291.11 CCU97593.1 - 2.2e-133 444.0 0.0 3e-133 443.6 0.0 1.1 1 0 0 1 1 1 1 Bystin HAUS5 PF14817.6 CCU97593.1 - 0.072 11.8 1.6 0.097 11.4 1.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Adaptin_N PF01602.20 CCU97594.1 - 2.5e-82 277.1 0.0 3.7e-82 276.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCU97594.1 - 1.1e-10 41.9 0.0 4e-10 40.0 0.0 2.0 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CCU97594.1 - 0.00026 21.0 2.5 2.4 8.6 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 CCU97594.1 - 0.00048 20.5 18.4 0.057 13.8 0.1 6.0 5 2 1 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 CCU97594.1 - 0.0082 16.6 13.9 2 9.0 0.2 6.2 5 1 1 6 6 6 1 HEAT-like repeat Phos_pyr_kin PF08543.12 CCU97595.1 - 2.8e-75 252.9 0.6 9.6e-59 198.7 0.2 2.1 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CCU97595.1 - 2.5e-35 122.2 3.1 2.8e-35 122.0 1.1 2.0 2 0 0 2 2 2 1 TENA/THI-4/PQQC family PfkB PF00294.24 CCU97595.1 - 0.00024 20.5 0.3 0.0013 18.1 0.0 2.0 2 0 0 2 2 2 1 pfkB family carbohydrate kinase SRP40_C PF05022.12 CCU97596.1 - 9.3e-26 90.5 2.0 9.3e-26 90.5 2.0 2.4 2 0 0 2 2 2 1 SRP40, C-terminal domain RRS1 PF04939.12 CCU97596.1 - 2.1 8.2 10.7 0.49 10.2 6.7 1.9 1 1 1 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) Presenilin PF01080.17 CCU97596.1 - 8.7 5.0 8.4 11 4.7 8.4 1.2 1 0 0 1 1 1 0 Presenilin Thiolase_N PF00108.23 CCU97597.1 - 6.6e-76 255.1 0.3 8.5e-76 254.7 0.3 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CCU97597.1 - 1.4e-47 160.4 0.3 3.4e-47 159.1 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CCU97597.1 - 0.00013 21.6 0.9 0.00031 20.4 0.9 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CCU97597.1 - 0.15 12.0 1.1 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SAPS PF04499.15 CCU97598.1 - 5.4e-128 427.8 0.7 5.4e-128 427.8 0.7 1.4 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Malate_synthase PF01274.22 CCU97599.1 - 8.4e-206 684.3 0.0 9.4e-206 684.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 CCU97599.1 - 0.068 12.3 0.0 0.15 11.2 0.0 1.6 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Gar1 PF04410.14 CCU97600.1 - 9.3e-34 116.4 0.2 2.2e-33 115.2 0.2 1.6 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region FA_desaturase PF00487.24 CCU97602.1 - 3.7e-22 79.4 27.5 1.1e-21 77.8 27.5 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DBR1 PF05011.13 CCU97603.1 - 1.3e-28 100.2 0.0 1.8e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 CCU97603.1 - 1.3e-08 35.6 0.0 1.9e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_M16_M PF16187.5 CCU97604.1 - 5.1e-94 314.7 0.0 2.4e-93 312.5 0.0 1.9 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CCU97604.1 - 2.6e-43 147.5 1.1 1.9e-41 141.5 0.0 3.6 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCU97604.1 - 2.2e-32 112.5 0.0 4.9e-21 75.6 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Phage_int_SAM_1 PF02899.17 CCU97604.1 - 0.011 16.0 0.3 1.7 9.0 0.0 3.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Enolase_C PF00113.22 CCU97605.1 - 2.1e-141 470.4 0.3 3e-141 469.9 0.3 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CCU97605.1 - 3.8e-57 192.1 0.1 6e-57 191.4 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CCU97605.1 - 7.3e-08 32.2 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CCU97605.1 - 0.0092 15.2 0.5 0.021 14.0 0.2 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Lactamase_B PF00753.27 CCU97606.1 - 0.0063 16.5 0.3 0.012 15.7 0.1 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 CCU97606.1 - 0.017 15.1 0.1 0.031 14.3 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain T2SSE_N PF05157.15 CCU97606.1 - 0.09 13.0 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain DUF1325 PF07039.11 CCU97607.1 - 1.5e-30 106.0 0.0 2.7e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain PNRC PF15365.6 CCU97607.1 - 4.5e-08 32.7 4.1 3.1e-07 30.0 4.1 2.7 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif Rrn6 PF10214.9 CCU97607.1 - 6.7e-08 31.5 0.4 6.7e-08 31.5 0.4 2.6 3 0 0 3 3 3 2 RNA polymerase I-specific transcription-initiation factor RF-1 PF00472.20 CCU97608.1 - 1.2e-37 128.4 2.3 3.1e-37 127.0 2.3 1.7 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.18 CCU97608.1 - 2.4e-22 79.7 1.2 2.1e-20 73.4 0.3 2.9 2 1 0 2 2 2 1 PCRF domain Adaptin_N PF01602.20 CCU97609.1 - 2.1e-85 287.3 17.1 3e-85 286.8 17.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 CCU97609.1 - 6.6e-55 184.9 0.1 1.6e-54 183.6 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 CCU97609.1 - 5.3e-54 181.6 0.0 1.7e-53 180.0 0.0 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.6 CCU97609.1 - 2.9e-11 43.6 5.6 0.0023 18.3 0.0 5.5 2 1 3 6 6 6 4 HEAT repeats Cnd1 PF12717.7 CCU97609.1 - 1.1e-08 35.3 10.4 4.2e-07 30.2 0.4 3.9 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CCU97609.1 - 3.2e-05 23.8 0.6 0.1 12.9 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat ParcG PF10274.9 CCU97609.1 - 0.00097 19.3 5.7 0.03 14.4 0.1 3.5 2 1 0 3 3 3 1 Parkin co-regulated protein DUF5578 PF17741.1 CCU97609.1 - 0.0033 16.9 1.3 0.0033 16.9 1.3 3.7 3 1 1 4 4 4 1 Family of unknown function (DUF5578) RTP1_C1 PF10363.9 CCU97609.1 - 0.013 15.7 6.2 0.071 13.3 0.0 3.5 2 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 CCU97609.1 - 0.019 14.5 3.3 1.8 8.1 1.1 3.3 2 1 2 4 4 4 0 CLASP N terminal HEAT_EZ PF13513.6 CCU97609.1 - 0.02 15.4 0.3 29 5.3 0.0 5.2 5 0 0 5 5 5 0 HEAT-like repeat PaaB PF06243.11 CCU97609.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Phenylacetic acid degradation B RNA_pol_Rpb1_5 PF04998.17 CCU97609.1 - 0.068 12.6 0.4 0.13 11.7 0.4 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 FANCI_S2 PF14676.6 CCU97609.1 - 1.6 9.0 6.0 23 5.2 0.1 3.5 2 1 1 3 3 3 0 FANCI solenoid 2 ABC_tran PF00005.27 CCU97610.1 - 1.8e-34 119.2 0.1 1.4e-16 61.3 0.0 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCU97610.1 - 7.3e-11 41.9 5.1 9.6e-05 21.9 0.3 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CCU97610.1 - 6.9e-09 35.9 3.1 0.19 11.5 0.9 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 CCU97610.1 - 3.9e-07 29.6 2.6 7.1e-07 28.8 2.6 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain AAA_15 PF13175.6 CCU97610.1 - 4e-06 26.8 1.8 0.13 12.0 0.4 3.3 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 CCU97610.1 - 5.6e-06 26.4 0.0 0.066 13.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 CCU97610.1 - 8e-06 26.3 0.2 0.024 15.1 0.2 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCU97610.1 - 1.7e-05 25.1 0.0 0.011 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCU97610.1 - 4.3e-05 24.0 0.1 0.037 14.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Fer4_6 PF12837.7 CCU97610.1 - 6.1e-05 22.9 1.8 0.00012 22.0 1.8 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain NACHT PF05729.12 CCU97610.1 - 8.6e-05 22.5 1.2 0.0078 16.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 CCU97610.1 - 0.00017 21.2 1.0 0.49 10.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_21 PF14697.6 CCU97610.1 - 0.0003 20.9 1.3 0.00065 19.8 1.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Rad17 PF03215.15 CCU97610.1 - 0.00036 20.5 0.0 0.54 10.2 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 CCU97610.1 - 0.00056 19.5 0.6 0.0074 15.8 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 CCU97610.1 - 0.00056 19.2 0.0 0.026 13.7 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Fer4_10 PF13237.6 CCU97610.1 - 0.00062 19.8 0.1 0.0014 18.7 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CCU97610.1 - 0.00069 19.7 0.9 0.0016 18.6 0.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CCU97610.1 - 0.00073 20.1 0.3 0.0018 18.8 0.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.22 CCU97610.1 - 0.00078 19.8 0.1 0.2 12.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 CCU97610.1 - 0.001 19.2 0.5 0.35 11.0 0.0 2.8 3 1 0 3 3 2 1 AAA domain Fer4_2 PF12797.7 CCU97610.1 - 0.0012 18.8 0.9 0.0025 17.8 0.9 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain AAA_24 PF13479.6 CCU97610.1 - 0.0015 18.3 0.9 0.35 10.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain Fer4_16 PF13484.6 CCU97610.1 - 0.0035 18.3 0.3 0.011 16.6 0.3 1.9 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain AAA_28 PF13521.6 CCU97610.1 - 0.0045 17.2 0.6 1.4 9.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CCU97610.1 - 0.0046 17.0 0.3 0.078 13.0 0.1 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_17 PF13534.6 CCU97610.1 - 0.0077 16.8 0.2 0.021 15.3 0.2 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_18 PF13238.6 CCU97610.1 - 0.01 16.4 0.2 4.2 7.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 CCU97610.1 - 0.013 15.7 0.0 7.7 6.8 0.0 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 CCU97610.1 - 0.014 15.1 3.7 0.34 10.5 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 CCU97610.1 - 0.018 15.1 0.1 5.9 7.0 0.1 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase VirE PF05272.11 CCU97610.1 - 0.026 14.2 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_23 PF13476.6 CCU97610.1 - 0.028 14.9 8.1 0.075 13.5 0.5 3.0 3 0 0 3 3 3 0 AAA domain Fer4_8 PF13183.6 CCU97610.1 - 0.032 14.7 0.1 0.085 13.3 0.1 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 CCU97610.1 - 0.036 13.7 0.0 13 5.4 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase AAA_30 PF13604.6 CCU97610.1 - 0.047 13.4 0.6 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CCU97610.1 - 0.091 12.8 1.4 9.2 6.3 0.1 3.1 2 2 0 2 2 2 0 AAA domain MeaB PF03308.16 CCU97610.1 - 0.13 11.2 0.3 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_4 PF12800.7 CCU97610.1 - 0.19 12.3 3.0 0.4 11.3 3.0 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_22 PF17179.4 CCU97610.1 - 0.24 12.3 1.8 0.44 11.4 0.9 1.9 2 0 0 2 2 1 0 4Fe-4S dicluster domain Roc PF08477.13 CCU97610.1 - 0.28 11.4 0.8 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 CCU97610.1 - 0.28 10.7 0.8 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CCU97610.1 - 0.6 10.1 3.5 2.2 8.3 0.2 3.1 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Fer4_3 PF12798.7 CCU97610.1 - 1.1 10.3 3.1 2.7 9.1 3.1 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain SNF2_N PF00176.23 CCU97612.1 - 1.5e-46 158.8 0.2 1.3e-45 155.7 0.2 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 CCU97612.1 - 0.00055 19.8 0.0 0.00096 19.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase KH_8 PF17903.1 CCU97613.1 - 2.4e-32 110.9 0.0 5.6e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CCU97613.1 - 0.00031 20.5 0.0 0.00061 19.6 0.0 1.5 1 0 0 1 1 1 1 KH domain FHA PF00498.26 CCU97614.1 - 5.1e-15 55.6 0.0 9.3e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 CCU97614.1 - 3e-10 39.6 11.5 5.3e-10 38.9 11.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CCU97614.1 - 3.2e-07 30.6 12.1 5.1e-07 29.9 12.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CCU97614.1 - 0.0001 22.5 6.0 0.00021 21.5 6.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CCU97614.1 - 0.0016 18.2 12.8 0.0027 17.5 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CCU97614.1 - 0.0017 18.4 3.0 0.0033 17.4 3.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CCU97614.1 - 0.029 14.3 10.6 0.046 13.7 10.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.6 CCU97614.1 - 0.055 13.7 1.3 0.12 12.7 1.3 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_3 PF13922.6 CCU97614.1 - 0.067 13.6 0.2 0.51 10.8 0.7 2.2 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx zf-C3HC4 PF00097.25 CCU97614.1 - 0.069 13.0 11.7 0.12 12.3 11.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 CCU97614.1 - 0.079 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Zn_ribbon_17 PF17120.5 CCU97614.1 - 0.94 9.1 7.0 1.7 8.3 7.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 CCU97614.1 - 3.2 7.7 6.7 5.5 7.0 6.7 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 CCU97614.1 - 5.5 6.9 13.1 2 8.4 10.4 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DEAD PF00270.29 CCU97615.1 - 1.9e-47 161.3 0.0 5e-47 159.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU97615.1 - 2.4e-31 108.3 0.0 8.6e-30 103.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU97615.1 - 0.00011 22.3 0.0 0.00038 20.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 CCU97615.1 - 0.016 14.0 0.2 0.11 11.2 0.0 2.3 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 GAT PF03127.14 CCU97615.1 - 0.15 12.3 1.3 0.28 11.5 0.2 2.0 2 0 0 2 2 2 0 GAT domain NYD-SP28 PF14772.6 CCU97615.1 - 1.2 9.2 10.2 0.16 12.0 3.6 2.7 2 0 0 2 2 2 0 Sperm tail IF-2B PF01008.17 CCU97616.1 - 1.4e-57 195.1 0.0 1.7e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pkinase PF00069.25 CCU97617.1 - 1.5e-57 195.0 0.0 1.9e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97617.1 - 7.5e-25 87.7 0.0 1.1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Got1 PF04178.12 CCU97617.1 - 1.7e-12 47.8 13.6 3e-12 47.0 13.6 1.4 1 0 0 1 1 1 1 Got1/Sft2-like family Kinase-like PF14531.6 CCU97617.1 - 0.0075 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.12 CCU97617.1 - 0.016 14.9 0.0 0.046 13.4 0.0 1.7 2 0 0 2 2 2 0 DSHCT (NUC185) domain Haspin_kinase PF12330.8 CCU97617.1 - 0.019 13.9 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CCU97617.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCU97617.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3040 PF11239.8 CCU97617.1 - 7.5 6.9 14.9 1.6 9.1 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Lipase_GDSL_2 PF13472.6 CCU97618.1 - 8.6e-10 39.3 1.5 1.6e-09 38.5 1.5 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CCU97618.1 - 1.1e-07 32.1 0.0 2e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sec23_trunk PF04811.15 CCU97619.1 - 6.9e-58 196.1 0.0 1.1e-57 195.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CCU97619.1 - 2.9e-23 81.6 0.0 7e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CCU97619.1 - 2.9e-16 59.2 4.9 4.8e-16 58.5 4.9 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CCU97619.1 - 1.2e-15 58.0 0.0 2.1e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CCU97619.1 - 1.8e-06 27.8 0.0 3.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CCU97619.1 - 0.003 16.9 0.6 0.0058 16.0 0.6 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain RRM_1 PF00076.22 CCU97620.1 - 7.4e-07 28.9 0.0 1.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 CCU97620.1 - 0.018 15.4 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 PWI domain DUF4619 PF15398.6 CCU97620.1 - 0.024 14.2 0.4 0.036 13.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) zf-CCCH PF00642.24 CCU97623.1 - 1.6e-14 53.4 28.3 1.9e-08 34.0 1.6 4.2 3 1 1 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCU97623.1 - 1e-10 41.3 25.5 3e-06 27.1 2.6 4.1 4 0 0 4 4 4 2 Zinc finger domain Torus PF16131.5 CCU97623.1 - 3.5e-05 24.4 17.3 0.009 16.7 0.1 3.9 2 1 2 4 4 4 2 Torus domain zf-CCCH_4 PF18044.1 CCU97623.1 - 6.6e-05 22.6 2.4 6.6e-05 22.6 2.4 4.6 5 1 0 5 5 5 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CCU97623.1 - 0.066 13.4 14.5 0.36 11.1 0.2 3.4 2 1 1 3 3 3 0 Zinc-finger containing family NPIP PF06409.11 CCU97623.1 - 0.081 12.0 1.0 0.13 11.3 1.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) zf-CCCH_2 PF14608.6 CCU97623.1 - 0.37 11.3 18.6 0.12 12.9 1.3 4.1 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger Rtf2 PF04641.12 CCU97624.1 - 2.3e-33 115.7 0.0 2.6e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger TALPID3 PF15324.6 CCU97624.1 - 0.13 9.9 3.1 0.15 9.7 3.1 1.0 1 0 0 1 1 1 0 Hedgehog signalling target TRAF6_Z2 PF18048.1 CCU97624.1 - 2.7 8.1 6.0 2.6 8.2 3.1 2.1 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Pkinase PF00069.25 CCU97626.1 - 2.5e-40 138.5 0.0 3e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97626.1 - 1.5e-16 60.5 0.0 2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCU97626.1 - 1.4e-05 25.2 0.6 5.9e-05 23.1 0.6 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CCU97626.1 - 6.5e-05 22.6 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 CCU97626.1 - 0.0089 15.4 0.0 0.032 13.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 CCU97626.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 CCU97626.1 - 0.045 13.1 0.1 0.097 12.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_20 PF00982.21 CCU97627.1 - 3.8e-147 490.8 0.0 4.8e-147 490.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CCU97627.1 - 1.4e-17 63.6 0.0 2.1e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Rep_2 PF01719.17 CCU97627.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Plasmid replication protein P16-Arc PF04699.14 CCU97628.1 - 2.1e-43 148.3 0.0 2.4e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Pkinase PF00069.25 CCU97629.1 - 9.7e-73 244.8 1.0 1.3e-72 244.3 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97629.1 - 7.6e-52 176.2 0.1 7.6e-52 176.2 0.1 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase PBD PF00786.28 CCU97629.1 - 6.2e-23 80.9 0.0 1.7e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 CCU97629.1 - 1.5e-10 41.5 0.9 3.2e-10 40.4 0.9 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 CCU97629.1 - 4.3e-06 25.8 0.0 4.3e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CCU97629.1 - 5e-06 26.0 0.0 5e-06 26.0 0.0 1.9 2 1 1 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 CCU97629.1 - 0.0019 17.2 0.4 0.0019 17.2 0.4 1.7 2 0 0 2 2 2 1 Haspin like kinase domain PH_11 PF15413.6 CCU97629.1 - 0.0075 16.7 1.3 0.13 12.7 1.3 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.23 CCU97629.1 - 0.087 12.7 7.0 0.09 12.7 0.1 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family AviRa PF11599.8 CCU97629.1 - 0.59 9.6 2.8 1.2 8.6 2.8 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa FF PF01846.19 CCU97631.1 - 3.3e-29 100.8 0.4 9.5e-11 41.7 0.0 4.6 4 0 0 4 4 4 4 FF domain WW PF00397.26 CCU97631.1 - 1.6e-07 31.3 11.8 0.00016 21.6 2.7 2.5 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 CCU97631.1 - 2.2e-05 25.0 11.3 0.035 14.8 0.3 5.2 3 1 2 5 5 5 3 p190-A and -B Rho GAPs FF domain HSP70 PF00012.20 CCU97632.1 - 1e-70 238.6 0.2 1.4e-70 238.1 0.2 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCU97632.1 - 3.8e-05 22.7 0.2 0.00032 19.6 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.8 CCU97632.1 - 0.00048 19.3 0.1 0.47 9.4 0.0 2.5 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; FtsA PF14450.6 CCU97632.1 - 0.0016 18.8 0.2 0.0063 16.9 0.1 2.0 2 0 0 2 2 2 1 Cell division protein FtsA Hydantoinase_A PF01968.18 CCU97632.1 - 0.048 12.9 1.0 0.49 9.6 0.1 2.3 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase VWA_3_C PF18571.1 CCU97632.1 - 0.19 11.6 1.3 2.2 8.2 0.1 3.1 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Guanylate_kin PF00625.21 CCU97633.1 - 1.9e-57 193.9 0.0 2.2e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 CCU97633.1 - 3.5e-08 34.0 0.3 1.1e-07 32.4 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CCU97633.1 - 2.2e-06 27.9 0.1 1.9e-05 24.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCU97633.1 - 6.9e-06 26.4 0.0 3.4e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCU97633.1 - 6.2e-05 23.0 0.0 0.00011 22.2 0.0 1.5 1 1 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 CCU97633.1 - 0.00018 22.1 0.0 0.00082 19.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CCU97633.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CCU97633.1 - 0.0013 19.1 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 CCU97633.1 - 0.0015 18.8 0.0 0.038 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CCU97633.1 - 0.0042 17.6 0.0 0.015 15.8 0.0 2.0 2 1 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 CCU97633.1 - 0.0062 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 CCU97633.1 - 0.0069 16.8 0.0 0.025 15.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CCU97633.1 - 0.0094 15.9 0.0 0.05 13.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 CCU97633.1 - 0.0096 15.7 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 CCU97633.1 - 0.014 15.6 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 CCU97633.1 - 0.019 14.9 0.0 0.063 13.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 CCU97633.1 - 0.027 14.2 0.1 0.058 13.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CCU97633.1 - 0.03 14.2 0.0 0.038 13.9 0.0 1.4 1 1 0 1 1 1 0 NTPase Rad17 PF03215.15 CCU97633.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Septin PF00735.18 CCU97633.1 - 0.09 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 CCU97633.1 - 0.097 12.6 0.0 0.097 12.6 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CCU97633.1 - 0.15 11.7 0.6 0.88 9.1 0.2 2.4 1 1 1 2 2 2 0 AAA domain DUF4485 PF14846.6 CCU97633.1 - 0.15 12.2 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) AAA_14 PF13173.6 CCU97633.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain CENP-T_C PF15511.6 CCU97634.1 - 1.6e-08 34.6 0.1 2e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CCU97634.1 - 0.00017 21.9 0.1 0.00021 21.7 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CCU97634.1 - 0.00022 21.3 0.1 0.00032 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CCU97634.1 - 0.00028 21.1 0.0 0.00055 20.2 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CCU97634.1 - 0.00052 20.3 0.0 0.00069 20.0 0.0 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CCU97634.1 - 0.051 13.6 0.0 0.059 13.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Nup35_RRM PF05172.13 CCU97635.1 - 7e-08 32.4 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 CCU97636.1 - 6e-68 229.1 0.0 7.2e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97636.1 - 2.7e-32 112.1 0.0 3.4e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCU97636.1 - 0.00039 19.5 0.0 0.0021 17.1 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CCU97636.1 - 0.0008 19.4 0.0 0.0018 18.2 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CCU97636.1 - 0.0016 17.8 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CCU97636.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 CCU97636.1 - 0.028 13.8 0.2 0.08 12.3 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tim17 PF02466.19 CCU97637.1 - 3.5e-12 46.7 0.1 6.6e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SAM_Exu PF18609.1 CCU97637.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Exuperantia SAM-like domain HAD_2 PF13419.6 CCU97638.1 - 3.1e-08 33.9 0.0 4.7e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCU97638.1 - 8.7e-06 26.2 0.0 3.3e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CCU97638.1 - 0.036 14.2 0.0 13 6.0 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Snf7 PF03357.21 CCU97639.1 - 2.6e-40 137.8 20.9 3.3e-40 137.5 20.9 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 CCU97639.1 - 0.052 14.0 4.1 0.12 12.8 1.0 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 CCU97639.1 - 0.097 13.0 11.2 6.8 7.0 0.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Uso1_p115_C PF04871.13 CCU97639.1 - 0.22 11.9 13.6 0.081 13.3 8.3 2.2 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Exonuc_VII_L PF02601.15 CCU97639.1 - 0.4 10.2 8.0 0.52 9.8 8.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin_2 PF01920.20 CCU97639.1 - 0.46 10.4 11.8 2.2 8.3 0.0 3.3 2 1 0 2 2 2 0 Prefoldin subunit GrpE PF01025.19 CCU97639.1 - 0.96 9.1 9.2 2.1 8.0 4.5 2.5 1 1 1 2 2 2 0 GrpE APG6_N PF17675.1 CCU97639.1 - 1.1 9.8 15.7 19 5.8 12.8 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 CCU97639.1 - 1.5 7.4 9.1 1.6 7.2 6.5 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF948 PF06103.11 CCU97639.1 - 5.8 7.2 6.7 4.5 7.6 2.8 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.8 CCU97639.1 - 8.2 6.5 10.8 1.9 8.6 1.9 2.8 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3138 PF11336.8 CCU97639.1 - 9.7 4.7 7.3 5.1 5.6 4.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) BAR PF03114.18 CCU97640.1 - 3.7e-34 118.4 0.2 1.4e-33 116.5 0.2 1.7 1 1 0 1 1 1 1 BAR domain Metallophos PF00149.28 CCU97641.1 - 2.6e-25 90.1 0.0 4.9e-25 89.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CCU97641.1 - 3.5e-20 72.1 0.0 7.1e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 CCU97641.1 - 1.7e-15 56.1 1.0 1.8e-05 24.4 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCU97641.1 - 4.2e-09 35.8 0.5 0.032 14.4 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCU97641.1 - 1e-07 31.8 1.4 0.029 14.7 0.1 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCU97641.1 - 5.5e-07 29.3 0.6 0.19 12.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCU97641.1 - 7.8e-07 28.7 2.0 0.0017 18.0 0.1 3.0 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.6 CCU97641.1 - 0.016 15.3 0.2 0.12 12.6 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCU97641.1 - 0.079 13.6 1.5 3.4 8.4 0.6 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCU97641.1 - 0.1 12.7 0.4 0.9 9.7 0.0 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 CCU97641.1 - 0.12 12.9 4.0 3 8.4 1.4 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CCU97641.1 - 0.13 13.1 1.1 7.7 7.6 0.2 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCU97641.1 - 0.42 10.9 2.4 0.97 9.8 0.6 2.6 3 1 0 3 3 2 0 Tetratricopeptide repeat Ribosomal_L21p PF00829.21 CCU97642.1 - 1e-18 67.5 0.2 2.9e-13 50.0 0.1 2.1 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein Dynamin_M PF01031.20 CCU97644.1 - 8.3e-108 359.9 0.0 1.7e-107 358.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CCU97644.1 - 7.4e-57 192.1 0.0 2e-56 190.7 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CCU97644.1 - 1.2e-26 92.6 3.1 1.2e-26 92.6 3.1 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CCU97644.1 - 0.0004 20.4 0.1 0.0044 17.1 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase TipAS PF07739.13 CCU97644.1 - 0.05 14.2 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain MBOAT PF03062.19 CCU97646.1 - 6.9e-17 61.8 6.1 7.5e-17 61.7 6.1 1.0 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family UIM PF02809.20 CCU97648.1 - 0.0067 16.3 2.8 0.0067 16.3 2.8 2.9 2 0 0 2 2 2 1 Ubiquitin interaction motif APG17 PF04108.12 CCU97648.1 - 0.024 13.8 2.6 0.04 13.0 2.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 TSP_NTD PF17804.1 CCU97648.1 - 0.082 13.2 1.1 0.12 12.6 0.2 1.6 2 0 0 2 2 2 0 Tail specific protease N-terminal domain Glutaredoxin2_C PF04399.13 CCU97648.1 - 0.55 10.1 3.3 14 5.6 0.4 2.8 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain RasGEF PF00617.19 CCU97649.1 - 1.2e-41 142.9 0.2 1.9e-41 142.2 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CCU97649.1 - 0.00016 21.9 0.0 0.00055 20.1 0.0 2.0 1 1 0 1 1 1 1 RasGEF N-terminal motif Sortilin-Vps10 PF15902.5 CCU97650.1 - 2.8e-220 731.7 0.0 1.8e-119 399.5 0.0 3.3 3 1 1 4 4 4 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CCU97650.1 - 9.7e-86 286.4 12.6 1.1e-45 156.0 1.2 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CCU97650.1 - 2.7e-06 26.5 45.8 0.78 10.0 0.4 12.0 13 0 0 13 13 13 5 BNR/Asp-box repeat PSII_BNR PF14870.6 CCU97650.1 - 0.01 15.1 3.7 1.8 7.7 0.0 4.4 4 2 1 5 5 5 0 Photosynthesis system II assembly factor YCF48 ADAM17_MPD PF16698.5 CCU97650.1 - 3.1 8.2 13.5 3.2 8.2 1.5 3.5 3 0 0 3 3 3 0 Membrane-proximal domain, switch, for ADAM17 Dus PF01207.17 CCU97651.1 - 2.2e-18 66.4 0.0 5.3e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) ASF1_hist_chap PF04729.13 CCU97652.1 - 6e-35 120.5 0.0 8e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Sterol_MT_C PF08498.10 CCU97653.1 - 2.9e-27 94.7 1.0 5.4e-27 93.9 1.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 CCU97653.1 - 1.8e-19 70.1 0.0 3.4e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCU97653.1 - 3.1e-18 66.0 0.0 5.1e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCU97653.1 - 1.6e-16 60.8 0.0 3.1e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCU97653.1 - 1.3e-14 54.4 0.0 1.8e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CCU97653.1 - 6.4e-14 51.9 0.0 8.8e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CCU97653.1 - 5.6e-12 46.3 0.0 1.5e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCU97653.1 - 9.7e-07 28.3 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CCU97653.1 - 1.3e-06 28.3 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 CCU97653.1 - 0.00034 20.2 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 CCU97653.1 - 0.00046 19.8 0.0 0.00088 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 CCU97653.1 - 0.0021 19.0 0.0 0.012 16.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 CCU97653.1 - 0.0051 16.4 0.0 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 CCU97653.1 - 0.021 15.0 0.0 0.067 13.3 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_3 PF01596.17 CCU97653.1 - 0.026 13.7 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.6 CCU97653.1 - 0.035 14.1 0.2 0.068 13.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 CCU97653.1 - 0.058 12.8 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 CCU97653.1 - 0.06 12.6 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Met_10 PF02475.16 CCU97653.1 - 0.063 13.0 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein LSM PF01423.22 CCU97654.1 - 2.3e-14 52.8 0.0 2.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DHO_dh PF01180.21 CCU97655.1 - 1.6e-94 316.4 0.0 3.3e-94 315.4 0.0 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CCU97655.1 - 0.089 11.8 1.9 2.8 6.9 2.1 2.6 2 1 0 2 2 2 0 FMN-dependent dehydrogenase zf-C2H2 PF00096.26 CCU97656.1 - 6e-22 76.8 23.6 9.8e-06 25.8 1.6 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCU97656.1 - 6.6e-21 73.7 21.3 1.9e-05 24.9 0.6 5.7 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCU97656.1 - 3.3e-12 46.1 22.0 0.0054 17.5 1.4 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCU97656.1 - 8e-06 26.0 3.4 0.38 11.1 0.1 3.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCU97656.1 - 0.00096 19.5 10.2 0.24 11.9 0.3 3.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 CCU97656.1 - 0.0023 18.5 0.9 6.4 7.5 0.0 3.4 1 1 2 3 3 3 1 FOXP coiled-coil domain zf-TRAF PF02176.18 CCU97656.1 - 0.027 15.1 8.5 0.048 14.3 0.9 3.1 2 1 1 3 3 3 0 TRAF-type zinc finger Viral_helicase1 PF01443.18 CCU97656.1 - 0.074 12.8 0.1 14 5.3 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase zf-C2H2_aberr PF17017.5 CCU97656.1 - 0.075 13.2 1.9 24 5.0 0.0 3.1 1 1 2 3 3 3 0 Aberrant zinc-finger zf-MYST PF17772.1 CCU97656.1 - 0.086 12.5 2.6 0.57 9.8 0.0 3.3 4 0 0 4 4 4 0 MYST family zinc finger domain ADK_lid PF05191.14 CCU97656.1 - 0.12 12.3 0.5 8.5 6.5 0.1 3.4 3 1 1 4 4 4 0 Adenylate kinase, active site lid zf-C2H2_6 PF13912.6 CCU97656.1 - 0.4 10.7 13.7 0.21 11.6 0.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CCU97656.1 - 0.97 9.2 15.6 8.3 6.3 0.5 4.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain SMC_N PF02463.19 CCU97657.1 - 3.5e-72 242.4 0.0 4.5e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCU97657.1 - 5.2e-24 84.8 0.0 1.8e-23 83.1 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CCU97657.1 - 2.7e-14 53.7 0.6 6e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CCU97657.1 - 1.1e-07 32.6 25.2 9.3e-07 29.5 14.2 4.8 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CCU97657.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CCU97657.1 - 0.0002 21.2 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 CCU97657.1 - 0.05 14.1 8.9 0.27 11.8 0.0 4.1 5 0 0 5 5 5 0 ABC transporter MPS2 PF17060.5 CCU97657.1 - 0.28 10.4 0.0 0.28 10.4 0.0 3.2 2 1 1 3 3 3 0 Monopolar spindle protein 2 FlaC_arch PF05377.11 CCU97657.1 - 0.4 11.1 7.9 7.1 7.1 0.0 5.9 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) AAA_22 PF13401.6 CCU97657.1 - 0.84 9.9 3.7 16 5.7 0.0 3.9 4 0 0 4 4 4 0 AAA domain MCM_bind PF09739.9 CCU97658.1 - 7.9e-70 235.9 0.0 1.8e-66 224.8 0.0 2.1 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor DUF2418 PF10332.9 CCU97658.1 - 5.6e-06 26.8 0.5 1.6e-05 25.3 0.5 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) CKS PF01111.19 CCU97659.1 - 2.5e-18 66.1 0.0 2.9e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Aldo_ket_red PF00248.21 CCU97660.1 - 3.3e-51 174.2 0.6 9.7e-50 169.4 0.6 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RCC1 PF00415.18 CCU97661.1 - 2.5e-29 101.6 7.7 8e-13 48.8 0.1 7.5 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CCU97661.1 - 8.2e-15 54.2 18.4 1.7e-09 37.3 0.2 6.8 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat HGTP_anticodon PF03129.20 CCU97662.1 - 6.5e-22 77.5 0.3 3.1e-21 75.3 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CCU97662.1 - 2.3e-10 40.8 0.0 6.5e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Mcp5_PH PF12814.7 CCU97663.1 - 6.4e-35 119.9 0.0 3.5e-34 117.5 0.0 2.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3584 PF12128.8 CCU97663.1 - 0.00016 19.4 21.9 0.00016 19.4 21.9 9.9 3 1 6 10 10 10 3 Protein of unknown function (DUF3584) Nop10p PF04135.12 CCU97664.1 - 4e-21 74.8 0.4 4.5e-21 74.6 0.4 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family EMP24_GP25L PF01105.24 CCU97665.1 - 3.3e-30 105.4 0.0 4.1e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD zf-UBR PF02207.20 CCU97666.1 - 3.1e-11 43.3 8.5 3.1e-11 43.3 8.5 3.5 3 1 0 3 3 3 2 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 CCU97666.1 - 0.0042 17.0 5.5 0.0042 17.0 5.5 3.7 3 2 1 4 4 4 1 PHD-finger Pyrid_oxidase_2 PF13883.6 CCU97667.1 - 1.9e-22 80.0 0.0 3e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PrsW-protease PF13367.6 CCU97667.1 - 1.5e-10 40.9 3.5 3e-10 39.9 3.5 1.6 1 1 0 1 1 1 1 PrsW family intramembrane metalloprotease DUF4234 PF14018.6 CCU97667.1 - 1.9 8.7 4.9 6.5 7.0 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) VRR_NUC PF08774.11 CCU97668.1 - 1.4e-19 70.1 0.2 4.3e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 VRR-NUC domain Myosin_head PF00063.21 CCU97669.1 - 3.8e-255 848.3 0.0 6.4e-255 847.6 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 CCU97669.1 - 7.1e-06 25.8 0.2 1.4e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Strep_SA_rep PF06696.11 CCU97669.1 - 0.037 14.0 2.4 0.2 11.7 0.5 3.1 2 0 0 2 2 2 0 Streptococcal surface antigen repeat AAA_22 PF13401.6 CCU97669.1 - 0.22 11.8 0.0 0.22 11.8 0.0 4.4 4 1 1 5 5 5 0 AAA domain MOZ_SAS PF01853.18 CCU97670.1 - 2.9e-75 251.8 0.2 4e-75 251.4 0.2 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CCU97670.1 - 3.3e-19 68.2 0.3 3.3e-19 68.2 0.3 3.3 5 1 0 5 5 5 1 MYST family zinc finger domain PHD PF00628.29 CCU97670.1 - 1.9e-12 46.9 27.4 3.3e-11 42.9 4.4 4.3 2 1 1 3 3 3 2 PHD-finger zf-RING_2 PF13639.6 CCU97670.1 - 0.0015 18.9 6.1 0.0015 18.9 6.1 3.6 3 1 0 3 3 3 1 Ring finger domain WD40 PF00400.32 CCU97671.1 - 2.6e-51 170.5 18.3 8.1e-10 39.1 1.9 6.6 5 1 1 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU97671.1 - 5.8e-16 58.6 0.9 0.00033 20.9 0.1 4.7 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCU97671.1 - 5.5e-08 31.9 3.6 0.0017 17.1 1.4 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CCU97671.1 - 2e-05 23.5 0.3 0.23 10.1 0.0 3.4 3 1 1 4 4 4 3 Nup133 N terminal like Ge1_WD40 PF16529.5 CCU97671.1 - 0.047 12.6 3.0 14 4.5 0.0 3.5 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1682 PF07946.14 CCU97671.1 - 0.14 11.3 4.3 0.22 10.7 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Kinesin PF00225.23 CCU97672.1 - 6e-24 84.6 0.0 8.3e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CCU97672.1 - 3.3e-10 40.1 0.0 1e-09 38.5 0.0 1.7 1 1 0 1 1 1 1 Microtubule binding DAHP_synth_1 PF00793.20 CCU97673.1 - 5.3e-98 327.3 0.0 6.2e-98 327.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family CBFD_NFYB_HMF PF00808.23 CCU97674.1 - 1.6e-17 63.6 0.2 2.6e-17 62.8 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YolD PF08863.10 CCU97674.1 - 0.14 12.2 1.4 1 9.4 0.8 2.0 2 0 0 2 2 2 0 YolD-like protein FTHFS PF01268.19 CCU97675.1 - 7e-259 859.7 0.0 2e-258 858.2 0.0 1.6 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CCU97675.1 - 2.5e-59 199.2 2.0 2.5e-59 199.2 2.0 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CCU97675.1 - 9.6e-35 119.4 0.1 5e-34 117.0 0.1 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ATPgrasp_N PF18130.1 CCU97675.1 - 7.4 7.2 9.3 1e+02 3.6 0.1 4.9 4 1 1 5 5 5 0 ATP-grasp N-terminal domain SAM_2 PF07647.17 CCU97676.1 - 6.2e-10 39.0 0.0 1.9e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CCU97676.1 - 2.2e-06 28.0 0.0 5.7e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 CCU97676.1 - 0.18 11.9 0.1 0.48 10.6 0.1 1.7 1 0 0 1 1 1 0 IGR protein motif YebO PF13974.6 CCU97676.1 - 0.21 11.7 5.1 0.57 10.3 5.1 1.7 1 0 0 1 1 1 0 YebO-like protein ATP-synt_ab PF00006.25 CCU97677.1 - 1.8e-62 210.8 0.0 3e-62 210.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CCU97677.1 - 6.9e-24 84.2 3.6 7.7e-24 84.0 1.4 2.3 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain AAA_16 PF13191.6 CCU97677.1 - 0.0073 16.7 0.0 0.021 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 CCU97677.1 - 0.012 14.9 1.0 0.017 14.3 0.2 1.6 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 CCU97677.1 - 0.015 15.2 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 CCU97677.1 - 0.042 13.8 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RnfC_N PF13375.6 CCU97677.1 - 0.044 13.7 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain AAA PF00004.29 CCU97677.1 - 0.057 13.8 0.0 0.63 10.5 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CCU97677.1 - 0.06 13.7 0.8 0.29 11.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CCU97677.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 CCU97677.1 - 0.068 12.5 0.4 0.15 11.4 0.4 1.6 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.22 CCU97677.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Septin PF00735.18 CCU97678.1 - 2e-99 332.4 0.0 2.5e-99 332.1 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CCU97678.1 - 1.3e-08 34.9 0.0 2.8e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCU97678.1 - 1.6e-06 27.8 0.3 0.00022 20.8 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCU97678.1 - 1.7e-06 28.1 0.1 9.6e-05 22.3 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 CCU97678.1 - 7.7e-05 22.1 0.0 7.7e-05 22.1 0.0 2.2 3 0 0 3 3 3 1 AIG1 family Gtr1_RagA PF04670.12 CCU97678.1 - 0.0013 18.1 2.5 0.0022 17.4 0.0 2.4 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 CCU97678.1 - 0.0026 17.8 0.1 0.9 9.6 0.1 2.4 1 1 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.18 CCU97678.1 - 0.0034 16.8 0.1 0.007 15.7 0.1 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.27 CCU97678.1 - 0.0074 16.8 0.1 0.014 15.9 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 CCU97678.1 - 0.0094 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 CCU97678.1 - 0.011 15.5 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCU97678.1 - 0.017 15.5 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CCU97678.1 - 0.022 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 CCU97678.1 - 0.026 14.7 0.2 0.065 13.5 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CCU97678.1 - 0.037 14.3 0.2 0.34 11.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 CCU97678.1 - 0.054 13.2 0.1 2.9 7.6 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 CCU97678.1 - 0.079 12.6 0.0 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 Ras family SCAMP PF04144.13 CCU97679.1 - 2.2e-50 171.3 13.3 2.6e-50 171.1 13.3 1.1 1 0 0 1 1 1 1 SCAMP family Peptidase_U4 PF03419.13 CCU97679.1 - 0.63 9.3 9.7 0.86 8.8 9.7 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF1700 PF08006.11 CCU97679.1 - 6.9 6.2 7.4 12 5.4 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Bromodomain PF00439.25 CCU97680.1 - 5.3e-42 141.8 0.9 5.9e-20 71.1 0.1 2.4 2 1 0 2 2 2 2 Bromodomain Sec39 PF08314.11 CCU97681.1 - 2.5e-08 32.9 0.0 4e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF3419 PF11899.8 CCU97682.1 - 1e-147 492.4 0.0 1.5e-147 491.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 CCU97682.1 - 2.2e-09 37.3 0.0 5.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCU97682.1 - 2.8e-09 37.6 0.0 3.5e-08 34.0 0.0 2.8 4 0 0 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCU97682.1 - 6.8e-08 32.1 0.0 5.4e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 CCU97682.1 - 1.9e-07 31.6 0.0 1.3e-05 25.7 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCU97682.1 - 2.8e-07 30.4 0.0 7e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCU97682.1 - 2e-06 28.5 0.0 6e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CCU97682.1 - 0.056 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Adaptin_N PF01602.20 CCU97683.1 - 4.6e-94 315.9 0.4 9.2e-94 314.9 0.4 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCU97683.1 - 4.6e-11 43.0 0.7 1.3e-08 35.0 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCU97683.1 - 0.00022 21.6 13.1 0.043 14.2 0.1 6.0 4 2 2 6 6 6 2 HEAT repeats HEAT PF02985.22 CCU97683.1 - 0.00035 20.6 2.1 6.4 7.3 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat RTP1_C1 PF10363.9 CCU97683.1 - 0.0041 17.3 0.9 0.38 10.9 0.0 4.2 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 CCU97683.1 - 0.077 12.7 2.2 0.12 12.1 0.5 2.2 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis P2_Phage_GpR PF06891.11 CCU97683.1 - 0.088 12.9 0.1 0.31 11.1 0.1 1.9 2 0 0 2 2 2 0 P2 phage tail completion protein R (GpR) DUF908 PF06012.12 CCU97683.1 - 1 8.7 0.0 1 8.7 0.0 3.2 4 1 0 4 4 4 0 Domain of Unknown Function (DUF908) GATase PF00117.28 CCU97684.1 - 0.02 14.6 0.0 0.081 12.7 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Tim54 PF11711.8 CCU97685.1 - 1.7e-47 162.0 0.0 2.6e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SH3BP5 PF05276.14 CCU97685.1 - 5.3 6.8 7.3 0.56 10.0 0.1 2.3 3 0 0 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) Methyltransf_25 PF13649.6 CCU97686.1 - 0.038 14.7 0.4 0.32 11.7 0.4 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CCU97686.1 - 0.061 13.1 0.1 0.25 11.1 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CCU97686.1 - 0.1 13.3 0.1 0.69 10.6 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain PNP_UDP_1 PF01048.20 CCU97687.1 - 4.2e-33 114.6 0.1 4.9e-33 114.3 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Pkinase PF00069.25 CCU97688.1 - 8.1e-56 189.3 0.0 4.4e-55 186.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain mRNA_triPase PF02940.15 CCU97688.1 - 1.5e-50 172.0 0.1 2.1e-50 171.5 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Pkinase_Tyr PF07714.17 CCU97688.1 - 4.4e-33 114.6 0.0 9.2e-33 113.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CCU97688.1 - 0.0059 16.0 0.6 0.011 15.2 0.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCU97688.1 - 0.014 15.3 2.0 0.079 12.9 0.2 2.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 CCU97688.1 - 0.019 14.5 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FAT PF02259.23 CCU97689.1 - 3.1e-114 381.8 0.1 3.1e-114 381.8 0.1 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 CCU97689.1 - 3.7e-68 230.0 0.0 8e-68 228.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MutS_V PF00488.21 CCU97689.1 - 2.6e-64 216.8 0.3 5.1e-64 215.8 0.3 1.5 1 0 0 1 1 1 1 MutS domain V DUF3385 PF11865.8 CCU97689.1 - 9.7e-60 201.1 0.1 2.6e-58 196.5 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CCU97689.1 - 1.7e-43 147.1 0.3 1.7e-43 147.1 0.3 3.0 3 0 0 3 3 2 1 FKBP12-rapamycin binding domain MutS_I PF01624.20 CCU97689.1 - 1.1e-33 115.9 0.0 2.4e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 CCU97689.1 - 1.2e-33 116.9 0.9 3.8e-33 115.3 0.9 1.9 1 0 0 1 1 1 1 MutS domain III HEAT_2 PF13646.6 CCU97689.1 - 8.2e-13 48.6 25.7 0.0068 16.8 0.0 10.7 8 3 4 12 12 12 4 HEAT repeats MutS_II PF05188.17 CCU97689.1 - 4.9e-11 43.1 0.0 1.5e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 MutS domain II HEAT PF02985.22 CCU97689.1 - 5e-07 29.4 21.0 0.34 11.3 0.0 10.6 10 0 0 10 10 10 2 HEAT repeat MutS_IV PF05190.18 CCU97689.1 - 1e-06 29.0 0.0 2.5e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV FATC PF02260.20 CCU97689.1 - 5.1e-06 26.2 0.0 1.8e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 CCU97689.1 - 0.00022 21.7 4.3 1.5 9.4 0.1 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_30 PF13604.6 CCU97689.1 - 0.037 13.8 1.1 0.57 9.9 0.6 2.8 3 0 0 3 3 3 0 AAA domain ANAPC3 PF12895.7 CCU97689.1 - 0.084 13.1 0.8 3.8 7.8 0.0 3.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 HEAT_EZ PF13513.6 CCU97689.1 - 0.16 12.5 0.0 0.14 12.7 0.2 12.1 14 1 1 15 15 12 0 HEAT-like repeat TPR_16 PF13432.6 CCU97689.1 - 0.32 11.7 11.4 0.61 10.8 0.3 5.3 5 0 0 5 5 3 0 Tetratricopeptide repeat PFU PF09070.11 CCU97690.1 - 1.3e-35 122.1 0.0 2.2e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 CCU97690.1 - 1.4e-27 96.7 0.1 2e-27 96.1 0.1 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 CCU97690.1 - 3.8e-25 87.6 17.0 0.00015 22.5 0.2 7.6 6 1 1 7 7 7 6 WD domain, G-beta repeat Endonuclease_NS PF01223.23 CCU97691.1 - 4.6e-55 186.9 0.0 7.1e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease PQ-loop PF04193.14 CCU97691.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 PQ loop repeat Aminotran_3 PF00202.21 CCU97692.1 - 4.5e-123 410.9 0.0 5.4e-123 410.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CCU97692.1 - 5.2e-05 22.6 0.0 9.4e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CCU97692.1 - 0.036 13.4 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 CCU97692.1 - 0.048 12.6 0.0 0.12 11.3 0.0 1.6 1 0 0 1 1 1 0 Aminotransferase class-V Ribosomal_L7Ae PF01248.26 CCU97694.1 - 2e-23 81.9 0.1 3.9e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SMN PF06003.12 CCU97694.1 - 0.0025 17.1 3.0 0.0039 16.5 3.0 1.2 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Eapp_C PF10238.9 CCU97694.1 - 0.079 13.0 2.3 0.12 12.5 2.3 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein Mre11_DNA_bind PF04152.14 CCU97694.1 - 0.13 12.6 9.0 0.15 12.3 8.1 1.6 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain DNA_pol_phi PF04931.13 CCU97694.1 - 0.19 9.8 8.9 0.24 9.5 8.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Hydrolase PF00702.26 CCU97694.1 - 0.31 11.3 3.3 1.4 9.1 2.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ferlin_C PF16165.5 CCU97694.1 - 0.32 10.9 12.4 0.63 10.0 12.4 1.5 1 0 0 1 1 1 0 Ferlin C-terminus DUF3807 PF12720.7 CCU97694.1 - 0.32 11.2 12.0 0.053 13.8 8.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) CDRT4 PF15213.6 CCU97694.1 - 0.52 10.9 4.1 0.85 10.2 4.1 1.4 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein DUF2722 PF10846.8 CCU97694.1 - 0.53 9.2 8.2 0.71 8.8 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NARP1 PF12569.8 CCU97694.1 - 1.5 7.7 14.5 2 7.3 14.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4887 PF16228.5 CCU97694.1 - 2.1 8.5 19.6 0.046 13.9 13.2 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4887) PPL5 PF18168.1 CCU97694.1 - 2.4 7.4 6.1 3.2 6.9 6.1 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Vfa1 PF08432.10 CCU97694.1 - 3.6 7.9 17.6 0.93 9.8 14.0 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 XRN_M PF17846.1 CCU97694.1 - 4.4 6.1 9.4 5.7 5.8 9.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Med19 PF10278.9 CCU97694.1 - 4.4 7.2 19.4 8.7 6.2 19.4 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Sec62 PF03839.16 CCU97694.1 - 6.9 6.1 11.2 11 5.4 11.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Paramyxo_ncap PF00973.19 CCU97694.1 - 7.5 5.3 7.6 10 4.9 7.6 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Peroxin-13_N PF04088.13 CCU97695.1 - 1.1e-46 158.7 0.1 1.8e-46 158.0 0.1 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region tRNA-synt_1b PF00579.25 CCU97695.1 - 1.8e-28 99.7 0.1 3.1e-28 99.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pex2_Pex12 PF04757.14 CCU97695.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Ribosomal_L16 PF00252.18 CCU97696.1 - 6.9e-42 142.6 0.1 8.8e-42 142.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF3212 PF11486.8 CCU97696.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) Rep_fac-A_C PF08646.10 CCU97698.1 - 1e-51 174.5 0.2 8.2e-50 168.3 0.0 2.5 3 0 0 3 3 3 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CCU97698.1 - 2.3e-35 120.4 0.2 1.1e-34 118.2 0.2 2.1 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 CCU97698.1 - 3.5e-12 46.1 0.0 2.7e-09 36.9 0.0 3.3 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 CCU97698.1 - 8e-08 32.2 0.2 2.1e-07 30.9 0.2 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF4539 PF15072.6 CCU97698.1 - 0.12 12.5 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) PH_9 PF15410.6 CCU97699.1 - 8.9e-09 35.7 0.1 0.00058 20.2 0.1 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 CCU97699.1 - 4.2e-07 30.4 0.1 0.0067 16.9 0.1 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 CCU97699.1 - 0.21 12.0 0.4 3.4 8.1 0.4 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Ist1 PF03398.14 CCU97700.1 - 1.3e-27 96.8 2.1 6.2e-16 58.8 0.0 2.0 1 1 1 2 2 2 2 Regulator of Vps4 activity in the MVB pathway DNA_primase_S PF01896.19 CCU97701.1 - 8.2e-50 169.3 0.0 2.2e-49 167.9 0.0 1.7 1 1 0 1 1 1 1 DNA primase small subunit Pyridoxal_deC PF00282.19 CCU97702.1 - 7.3e-69 232.3 0.0 1.1e-68 231.6 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CCU97702.1 - 3.7e-05 22.8 0.0 5.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CCU97702.1 - 0.0003 20.2 0.1 0.00052 19.4 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Pkinase PF00069.25 CCU97703.1 - 1.7e-72 244.0 0.1 2.3e-72 243.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97703.1 - 2.8e-42 144.8 0.0 3.9e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CCU97703.1 - 8.2e-32 109.2 0.0 3.6e-16 59.1 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 CCU97703.1 - 1.2e-06 28.0 0.0 2.2e-05 23.9 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CCU97703.1 - 0.0023 16.8 0.0 0.0051 15.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CCU97703.1 - 0.016 14.2 0.1 0.029 13.3 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain BRCA-2_OB1 PF09103.10 CCU97704.1 - 4.4e-30 104.2 0.0 6.2e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 CCU97704.1 - 6.1e-06 26.0 0.9 9.9e-06 25.3 0.9 1.3 1 0 0 1 1 1 1 BRCA2, helical SIS PF01380.22 CCU97705.1 - 6.4e-61 204.0 0.4 4.6e-34 117.1 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CCU97705.1 - 1.1e-17 64.5 0.0 2.4e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CCU97705.1 - 3.4e-12 46.3 0.0 7.6e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CCU97705.1 - 0.0012 17.8 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II YoeB_toxin PF06769.14 CCU97705.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 YoeB-like toxin of bacterial type II toxin-antitoxin system DEAD_2 PF06733.15 CCU97706.1 - 4.5e-49 166.4 0.0 7.3e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CCU97706.1 - 9.4e-26 91.0 0.0 3e-25 89.4 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.11 CCU97706.1 - 0.023 14.4 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Helical and beta-bridge domain MAP65_ASE1 PF03999.12 CCU97706.1 - 0.043 12.5 1.6 0.13 11.0 0.0 2.0 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) YabA PF06156.13 CCU97708.1 - 0.034 14.8 6.2 0.034 14.8 6.2 4.7 1 1 4 5 5 5 0 Initiation control protein YabA DUF1848 PF08902.11 CCU97708.1 - 1.7 8.3 4.6 3.1 7.5 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) ATG16 PF08614.11 CCU97708.1 - 2.3 8.4 64.2 0.33 11.2 32.1 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 CCU97708.1 - 2.7 6.5 30.6 3.7 6.1 26.3 2.1 1 1 1 2 2 2 0 AAA domain Mod_r PF07200.13 CCU97708.1 - 2.9 8.0 47.7 2.6 8.1 12.4 3.4 1 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein HMMR_N PF15905.5 CCU97708.1 - 4 6.8 50.5 0.38 10.2 22.2 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal EzrA PF06160.12 CCU97708.1 - 5.5 5.0 35.8 2.3 6.3 23.3 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 CCU97708.1 - 8.5 5.2 51.1 4.6 6.0 20.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Ribosomal_S10 PF00338.22 CCU97709.1 - 3.4e-27 94.5 0.4 4.1e-27 94.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L27A PF00828.19 CCU97710.1 - 6.6e-20 72.1 0.0 9.7e-20 71.5 0.0 1.2 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 3HCDH_N PF02737.18 CCU97712.1 - 1.2e-55 188.2 6.0 1.7e-55 187.7 6.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CCU97712.1 - 2.9e-32 111.1 0.0 8e-32 109.7 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 CCU97712.1 - 0.00034 20.9 0.4 0.00072 19.8 0.4 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 CCU97712.1 - 0.002 17.7 1.9 0.0048 16.5 1.9 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 CCU97712.1 - 0.0024 17.2 1.5 0.0046 16.2 1.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 CCU97712.1 - 0.017 14.5 0.2 0.023 14.0 0.2 1.3 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.23 CCU97712.1 - 0.017 15.1 1.6 0.047 13.7 1.6 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF1188 PF06690.11 CCU97712.1 - 0.036 13.6 1.4 0.1 12.1 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1188) Pyr_redox PF00070.27 CCU97712.1 - 0.048 14.2 0.6 0.091 13.3 0.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 CCU97712.1 - 0.049 13.8 5.9 1.3 9.2 5.9 2.2 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ribosomal_L11 PF00298.19 CCU97712.1 - 0.093 13.2 0.7 0.54 10.8 0.2 2.4 2 0 0 2 2 2 0 Ribosomal protein L11, RNA binding domain ApbA PF02558.16 CCU97712.1 - 0.11 12.1 0.6 0.17 11.5 0.6 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PglD_N PF17836.1 CCU97712.1 - 0.19 12.4 0.7 0.7 10.6 0.2 2.1 1 1 0 2 2 2 0 PglD N-terminal domain F420_oxidored PF03807.17 CCU97712.1 - 0.3 11.7 3.9 6.6 7.4 3.9 2.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glycos_transf_2 PF00535.26 CCU97713.1 - 9e-33 113.5 0.0 1.1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CCU97713.1 - 1.4e-12 48.0 0.0 2.3e-12 47.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CCU97713.1 - 0.00021 20.8 0.0 0.0005 19.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 CCU97713.1 - 0.00042 19.9 0.0 0.00057 19.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 CCU97713.1 - 0.00099 18.8 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_4 PF13704.6 CCU97713.1 - 0.069 13.7 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 WD40 PF00400.32 CCU97714.1 - 1.3e-25 89.1 8.0 1.7e-08 34.9 0.2 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Sof1 PF04158.14 CCU97714.1 - 4.2e-24 84.6 10.8 7.2e-24 83.9 10.8 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 CCU97714.1 - 6.2e-09 36.0 0.0 0.032 14.5 0.0 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCU97714.1 - 0.00073 19.5 0.0 0.0023 17.9 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Pribosyltran_N PF13793.6 CCU97715.1 - 1.4e-42 144.3 0.2 5.3e-42 142.4 0.0 2.0 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CCU97715.1 - 1.2e-34 119.9 0.1 2.5e-34 118.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CCU97715.1 - 1.4e-08 34.4 0.3 8.7e-08 31.8 0.2 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCU97715.1 - 0.026 13.9 0.1 0.044 13.2 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase RNase_PH PF01138.21 CCU97715.1 - 0.071 13.6 0.1 1.2 9.6 0.1 2.3 2 0 0 2 2 2 0 3' exoribonuclease family, domain 1 CheW PF01584.19 CCU97715.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 CheW-like domain LSM PF01423.22 CCU97716.1 - 8.3e-16 57.4 0.7 1e-15 57.2 0.7 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 CCU97716.1 - 0.1 12.5 0.5 0.16 11.9 0.5 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain XPG_N PF00752.17 CCU97717.1 - 3.6e-26 91.6 0.0 6.6e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CCU97717.1 - 1.9e-24 85.8 0.0 3.2e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 XPG I-region TPR_2 PF07719.17 CCU97717.1 - 0.00055 19.9 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat 5_3_exonuc PF01367.20 CCU97717.1 - 0.023 15.3 0.0 0.044 14.4 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TPR_1 PF00515.28 CCU97717.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat XPG_I_2 PF12813.7 CCU97717.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing HCNGP PF07818.13 CCU97718.1 - 1.3e-16 61.0 0.0 2.6e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein TFIIIC_sub6 PF10419.9 CCU97718.1 - 2.5e-06 27.3 0.1 6.9e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 TFIIIC subunit triple barrel domain UDPG_MGDP_dh_N PF03721.14 CCU97719.1 - 1.4e-56 191.1 0.1 2.2e-56 190.4 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 CCU97719.1 - 9e-37 125.7 0.1 2.6e-36 124.2 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 CCU97719.1 - 3.6e-31 107.2 0.0 6.9e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain F420_oxidored PF03807.17 CCU97719.1 - 0.01 16.4 0.0 1.7 9.3 0.0 2.8 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 CCU97719.1 - 0.011 16.0 0.4 0.071 13.4 0.0 2.5 4 0 0 4 4 4 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 CCU97719.1 - 0.045 13.9 0.0 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Abhydrolase_6 PF12697.7 CCU97720.1 - 0.18 12.4 9.3 0.12 13.0 6.8 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase family Ribosomal_L1 PF00687.21 CCU97721.1 - 4.7e-58 196.3 0.1 6.4e-58 195.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pyr_redox_2 PF07992.14 CCU97722.1 - 2.2e-17 63.2 0.0 8.4e-15 54.8 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCU97722.1 - 6.3e-15 55.5 0.0 1.4e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CCU97722.1 - 0.094 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) 3-HAO PF06052.12 CCU97724.1 - 1.2e-32 112.6 0.1 1.3e-32 112.5 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 CCU97724.1 - 0.00079 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 CCU97724.1 - 0.0079 15.8 0.0 0.0097 15.5 0.0 1.1 1 0 0 1 1 1 1 Cupin CRISPR_Cas2 PF09827.9 CCU97724.1 - 0.029 14.6 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas2 Cupin_3 PF05899.12 CCU97724.1 - 0.15 11.7 0.1 0.44 10.3 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF861) LSM PF01423.22 CCU97725.1 - 3.7e-18 65.0 0.9 4.2e-18 64.8 0.9 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.21 CCU97726.1 - 2.9e-17 62.6 0.0 5.1e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CCU97726.1 - 0.0043 17.4 0.0 0.29 11.5 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein L5 adh_short PF00106.25 CCU97727.1 - 1.1e-25 90.2 4.8 2.1e-24 86.0 4.8 2.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCU97727.1 - 3.6e-22 79.1 4.7 5.1e-21 75.3 4.7 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCU97727.1 - 2.7e-08 33.9 0.1 4.4e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CCU97727.1 - 0.0004 19.9 1.0 0.0016 18.0 1.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 CCU97727.1 - 0.026 14.3 0.7 0.088 12.6 0.3 1.9 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.15 CCU97727.1 - 0.093 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YjeF_N PF03853.15 CCU97727.1 - 0.12 12.3 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_10 PF13460.6 CCU97727.1 - 0.83 9.5 3.7 6.9 6.5 3.7 2.4 1 1 0 1 1 1 0 NAD(P)H-binding Clathrin PF00637.20 CCU97728.1 - 4e-16 59.2 0.1 1.6e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 CCU97728.1 - 0.084 13.3 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 ELYS PF13934.6 CCU97728.1 - 0.096 12.7 1.2 0.53 10.2 0.2 2.4 2 0 0 2 2 2 0 Nuclear pore complex assembly Zn_ribbon_17 PF17120.5 CCU97728.1 - 0.11 12.1 1.2 0.26 11.0 1.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 CCU97728.1 - 0.22 11.9 4.1 0.14 12.5 0.8 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 CCU97728.1 - 2.1 8.3 8.1 0.19 11.6 2.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CCU97728.1 - 3.4 8.0 5.2 0.99 9.7 1.2 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain GRIM-19 PF06212.12 CCU97729.1 - 1.9e-29 102.3 0.0 2.2e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Nop14 PF04147.12 CCU97730.1 - 3.8e-265 882.4 30.5 4.4e-265 882.2 30.5 1.0 1 0 0 1 1 1 1 Nop14-like family 14-3-3 PF00244.20 CCU97732.1 - 3.6e-107 356.9 4.4 4.1e-107 356.7 4.4 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 CCU97732.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF Adaptin_N PF01602.20 CCU97733.1 - 1.5e-98 330.6 0.9 1.9e-98 330.4 0.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CCU97733.1 - 1.2e-19 70.6 0.0 2.1e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain RasGEF_N_2 PF14663.6 CCU97733.1 - 0.0015 18.9 2.2 0.14 12.6 0.2 3.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT PF02985.22 CCU97733.1 - 0.0025 17.9 4.0 7 7.2 0.2 4.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 CCU97733.1 - 0.0028 18.0 10.5 0.014 15.7 0.8 3.9 3 1 2 5 5 5 2 HEAT repeats RTP1_C1 PF10363.9 CCU97733.1 - 0.011 15.9 6.0 0.012 15.8 0.6 3.4 2 1 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 RRN3 PF05327.11 CCU97734.1 - 7.3e-113 378.0 0.0 9.5e-113 377.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Ras PF00071.22 CCU97735.1 - 1.6e-45 154.6 0.0 2e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCU97735.1 - 4.4e-25 88.2 0.0 7.5e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU97735.1 - 2.5e-06 27.0 0.0 3.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCU97735.1 - 0.0079 15.6 0.0 0.012 14.9 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF5118 PF17162.4 CCU97735.1 - 0.038 13.8 0.1 0.073 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) STAS PF01740.21 CCU97735.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.5 1 1 0 1 1 1 0 STAS domain G-alpha PF00503.20 CCU97735.1 - 0.26 10.4 1.4 7.4 5.6 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit RPA43_OB PF17875.1 CCU97736.1 - 4.2e-18 66.1 0.1 4.2e-18 66.1 0.1 5.9 2 2 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 CCU97736.1 - 1.1e-06 28.9 0.0 2.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Thioredoxin PF00085.20 CCU97737.1 - 1.8e-26 92.1 0.0 2.3e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CCU97737.1 - 2e-11 44.3 0.2 9e-10 39.0 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CCU97737.1 - 6.2e-06 26.5 0.0 1.1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CCU97737.1 - 4.5e-05 23.2 0.0 5.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CCU97737.1 - 5.3e-05 23.3 0.0 8.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 CCU97737.1 - 0.00019 21.3 0.0 0.00024 21.0 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 CCU97737.1 - 0.0017 18.3 0.0 0.0027 17.6 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCU97737.1 - 0.0026 17.5 0.1 0.051 13.3 0.0 1.9 1 1 1 2 2 2 1 Redoxin Glutaredoxin PF00462.24 CCU97737.1 - 0.0036 17.5 0.0 0.0076 16.4 0.0 1.6 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CCU97737.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain DUF836 PF05768.14 CCU97737.1 - 0.046 14.1 0.0 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) OST3_OST6 PF04756.13 CCU97737.1 - 0.091 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family KIAA1328 PF15369.6 CCU97737.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 HyaE PF07449.11 CCU97737.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Methyltransf_16 PF10294.9 CCU97738.1 - 7.8e-15 55.0 0.0 2.5e-11 43.6 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 CCU97738.1 - 0.001 18.7 0.1 0.002 17.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CRAL_TRIO_2 PF13716.6 CCU97738.1 - 0.0023 18.1 0.0 0.0062 16.7 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Methyltransf_25 PF13649.6 CCU97738.1 - 0.0038 17.9 0.1 0.016 15.9 0.1 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCU97738.1 - 0.078 12.8 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Flu_NS1 PF00600.19 CCU97738.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) RasGAP PF00616.19 CCU97738.1 - 0.23 11.1 0.0 3.5 7.3 0.0 2.2 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase TetR_C_28 PF17937.1 CCU97738.1 - 2.5 8.6 9.9 3 8.4 0.0 5.9 6 0 0 6 6 6 0 Tetracyclin repressor-like, C-terminal domain MT-A70 PF05063.14 CCU97739.1 - 2.3e-53 180.7 0.0 4.3e-53 179.8 0.0 1.4 1 1 0 1 1 1 1 MT-A70 SCP2 PF02036.17 CCU97741.1 - 7.9e-24 84.1 1.5 9.2e-24 83.9 1.5 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CCU97741.1 - 0.00095 19.4 0.5 0.0011 19.2 0.5 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Bot1p PF12298.8 CCU97742.1 - 6.5e-23 81.8 0.0 8.5e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 CCU97742.1 - 0.00039 20.6 0.1 0.00039 20.6 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 UPF0240 PF06784.11 CCU97742.1 - 0.0023 18.0 0.2 0.061 13.4 0.0 2.4 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0240) His_Phos_2 PF00328.22 CCU97743.1 - 4.6e-73 246.8 0.1 6.1e-73 246.4 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CCU97743.1 - 3.3e-40 136.1 0.1 9e-40 134.7 0.1 1.8 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CCU97743.1 - 1.1e-06 28.4 0.0 2.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain LETM1 PF07766.13 CCU97744.1 - 1.2e-11 44.4 7.7 1.2e-09 38.0 0.8 2.2 1 1 1 2 2 2 2 LETM1-like protein LSM PF01423.22 CCU97745.1 - 0.0036 17.0 0.1 0.0055 16.4 0.1 1.3 1 0 0 1 1 1 1 LSM domain QueC PF06508.13 CCU97748.1 - 0.021 14.3 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Pex24p PF06398.11 CCU97749.1 - 4.1e-26 91.8 4.2 1.4e-25 90.0 4.2 1.8 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Spt20 PF12090.8 CCU97750.1 - 5.4e-29 101.5 1.4 2.6e-27 96.0 0.0 2.9 2 1 0 2 2 2 1 Spt20 family PINIT PF14324.6 CCU97751.1 - 1.4e-28 100.1 0.0 2.4e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 CCU97751.1 - 1.6e-19 69.3 6.1 2.8e-19 68.6 6.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CCU97751.1 - 2.7e-07 30.3 1.2 5e-07 29.4 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 CCU97751.1 - 0.03 14.1 3.6 1.6 8.5 0.0 3.6 4 0 0 4 4 4 0 SAP domain Rad50_zn_hook PF04423.14 CCU97751.1 - 0.22 11.4 1.1 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 CCU97751.1 - 0.24 11.3 1.8 0.54 10.2 1.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CCU97751.1 - 0.94 9.7 5.2 1.9 8.7 5.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CCU97751.1 - 4.3 7.3 5.9 9 6.2 5.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MgsA_C PF12002.8 CCU97752.1 - 2.6e-46 157.6 0.1 9.5e-46 155.8 0.0 1.8 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.29 CCU97752.1 - 6.7e-15 55.7 0.0 1.1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCU97752.1 - 1.4e-13 50.8 0.0 4.1e-13 49.4 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCU97752.1 - 3.8e-08 33.9 5.2 0.00058 20.3 0.0 2.9 1 1 2 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CCU97752.1 - 1.1e-07 31.9 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCU97752.1 - 3.1e-07 30.8 0.1 4.7e-06 26.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CCU97752.1 - 3.6e-06 27.1 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CCU97752.1 - 4.1e-06 27.0 0.9 1.3e-05 25.5 0.1 2.1 2 0 0 2 2 2 1 AAA C-terminal domain Mg_chelatase PF01078.21 CCU97752.1 - 4.9e-06 26.1 0.3 0.075 12.4 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CCU97752.1 - 6.4e-05 22.7 0.0 0.021 14.5 0.1 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_2 PF07724.14 CCU97752.1 - 0.00015 21.9 0.0 0.00022 21.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 CCU97752.1 - 0.00016 22.1 0.7 0.13 12.5 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 CCU97752.1 - 0.00078 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCU97752.1 - 0.0019 18.0 0.1 0.011 15.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CCU97752.1 - 0.002 18.1 0.4 0.53 10.1 0.0 2.3 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 CCU97752.1 - 0.0024 17.1 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 CCU97752.1 - 0.0026 17.9 0.0 0.0052 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 CCU97752.1 - 0.0033 17.5 0.0 0.0064 16.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain NACHT PF05729.12 CCU97752.1 - 0.0038 17.2 0.0 0.0088 16.0 0.0 1.7 1 1 0 1 1 1 1 NACHT domain DUF815 PF05673.13 CCU97752.1 - 0.004 16.3 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CCU97752.1 - 0.0045 16.5 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 CCU97752.1 - 0.0051 17.4 0.0 0.0087 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CCU97752.1 - 0.0061 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 CCU97752.1 - 0.0096 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.27 CCU97752.1 - 0.027 15.0 0.0 0.053 14.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 CCU97752.1 - 0.028 14.6 0.2 0.1 12.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 CCU97752.1 - 0.03 13.7 0.2 0.84 9.0 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein TIP49 PF06068.13 CCU97752.1 - 0.038 13.2 0.0 0.068 12.4 0.0 1.4 1 1 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 CCU97752.1 - 0.042 13.8 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 NTPase cobW PF02492.19 CCU97752.1 - 0.069 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 CCU97752.1 - 0.079 13.0 0.0 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_pol3_delta2 PF13177.6 CCU97752.1 - 0.08 12.7 0.1 0.19 11.5 0.1 1.4 1 1 0 1 1 1 0 DNA polymerase III, delta subunit RNA_helicase PF00910.22 CCU97752.1 - 0.092 13.1 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 CCU97752.1 - 0.11 11.5 0.1 0.21 10.6 0.1 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein MCM PF00493.23 CCU97752.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_17 PF13207.6 CCU97752.1 - 0.24 11.8 0.1 0.85 10.1 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 CCU97752.1 - 0.28 10.7 2.6 1.2 8.7 0.1 2.6 2 1 0 2 2 2 0 AAA domain DUF543 PF04418.12 CCU97753.1 - 5.1e-28 96.9 0.3 8.7e-28 96.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Apolipoprotein PF01442.18 CCU97753.1 - 0.003 17.5 2.7 0.0044 16.9 2.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CCU97753.1 - 0.0076 16.8 5.1 0.95 10.1 1.2 3.1 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 CCU97753.1 - 0.019 15.0 2.2 0.027 14.6 2.2 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF2959 PF11172.8 CCU97753.1 - 0.069 13.3 2.4 0.093 12.9 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) YtxH PF12732.7 CCU97753.1 - 0.081 13.5 10.9 1.4 9.5 0.2 3.1 2 1 1 3 3 3 0 YtxH-like protein ssDBP_DBD PF18361.1 CCU97753.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain CsbD PF05532.12 CCU97753.1 - 0.3 11.0 4.2 13 5.8 0.0 2.4 2 0 0 2 2 2 0 CsbD-like zf-CpG_bind_C PF12269.8 CCU97754.1 - 1.9e-06 27.9 0.0 5.7e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain Pkinase PF00069.25 CCU97755.1 - 9e-32 110.5 0.0 1.8e-16 60.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97755.1 - 3.4e-15 56.0 0.0 1.2e-07 31.2 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCU97755.1 - 6.5e-06 25.7 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like PEX11 PF05648.14 CCU97756.1 - 1.8e-18 66.8 0.0 2.2e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Ribosomal_S17 PF00366.20 CCU97757.1 - 4.6e-21 74.7 2.4 4.7e-21 74.7 1.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 Zds_C PF08632.10 CCU97758.1 - 1.8e-22 78.8 0.3 3.9e-22 77.7 0.3 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term TMEM252 PF15664.5 CCU97758.1 - 0.015 15.0 0.1 0.049 13.3 0.1 1.9 1 0 0 1 1 1 0 Transmembrane protein 252 family Smr PF01713.21 CCU97759.1 - 5e-10 39.6 0.2 2.2e-09 37.5 0.1 2.3 2 0 0 2 2 2 1 Smr domain DMA PF03474.14 CCU97759.1 - 0.0071 15.9 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 DMRTA motif CUE PF02845.16 CCU97759.1 - 0.012 15.3 0.0 1.5 8.6 0.0 3.2 3 0 0 3 3 3 0 CUE domain MFS_1 PF07690.16 CCU97760.1 - 3.2e-42 144.7 69.3 1.1e-20 73.8 29.7 3.4 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 CCU97760.1 - 5.9e-40 137.5 39.4 3.4e-17 62.4 4.3 4.3 4 0 0 4 4 4 4 Sugar (and other) transporter Urb2 PF10441.9 CCU97761.1 - 6.5e-48 163.4 3.8 2.6e-46 158.2 0.8 4.3 4 1 0 4 4 4 1 Urb2/Npa2 family TBD PF12845.7 CCU97761.1 - 0.23 11.4 1.3 0.87 9.5 0.4 2.3 2 0 0 2 2 2 0 TBD domain Ribosomal_L36 PF00444.18 CCU97762.1 - 6.7e-17 61.4 10.2 9.5e-17 60.9 10.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 NTP_transferase PF00483.23 CCU97763.1 - 6.5e-41 140.5 0.0 9.5e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CCU97763.1 - 3.8e-08 33.9 1.3 5.3e-08 33.4 0.2 1.9 2 0 0 2 2 2 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 CCU97763.1 - 1.2e-06 28.5 0.1 2.9e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase IspD PF01128.19 CCU97763.1 - 0.0034 17.2 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NIR_SIR PF01077.22 CCU97765.1 - 8.1e-48 161.9 0.0 8.7e-41 139.1 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 CCU97765.1 - 2.9e-26 92.4 0.0 5.3e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 CCU97765.1 - 4.7e-26 90.4 0.0 3.5e-12 46.0 0.0 3.0 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.19 CCU97765.1 - 2.2e-09 37.4 0.7 4.9e-09 36.3 0.7 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg TPR_6 PF13174.6 CCU97765.1 - 0.1 13.3 1.8 16 6.4 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CCU97765.1 - 0.25 11.6 1.7 5 7.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat RNB PF00773.19 CCU97766.1 - 6.4e-93 311.6 0.0 8.5e-93 311.2 0.0 1.1 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 CCU97766.1 - 8.6e-21 74.2 0.0 1.8e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CCU97766.1 - 5.1e-18 64.8 0.0 1e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 CCU97766.1 - 8.9e-16 57.7 0.0 2.2e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 CCU97766.1 - 8.6e-11 42.2 0.1 2e-10 41.0 0.1 1.7 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 CCU97766.1 - 2.1e-06 27.8 0.0 0.00014 22.0 0.0 3.2 3 0 0 3 3 3 1 Cold shock domain DUF3379 PF11859.8 CCU97766.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) NDK PF00334.19 CCU97767.1 - 3.5e-51 172.8 0.0 4.5e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Sin_N PF04801.13 CCU97768.1 - 5.2e-29 101.7 0.0 6.5e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region UBM PF14377.6 CCU97768.1 - 0.043 13.3 0.3 0.14 11.7 0.3 2.0 1 0 0 1 1 1 0 Ubiquitin binding region TAFII55_N PF04658.13 CCU97769.1 - 2.1e-52 177.1 0.0 3.7e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region DUF1741 PF08427.10 CCU97770.1 - 1e-19 71.2 0.6 1.8e-19 70.4 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Cation_efflux PF01545.21 CCU97771.1 - 3.2e-46 157.6 14.6 3.2e-46 157.6 14.6 1.6 2 1 0 2 2 2 1 Cation efflux family ZT_dimer PF16916.5 CCU97771.1 - 0.013 15.7 0.3 0.013 15.7 0.3 1.9 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter RAI1 PF08652.11 CCU97772.1 - 3.7e-17 62.3 0.0 7e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease GTP_EFTU PF00009.27 CCU97773.1 - 1.8e-54 184.2 0.1 2.7e-54 183.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCU97773.1 - 1.3e-42 144.7 0.0 2.5e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCU97773.1 - 6.7e-15 55.2 0.3 2e-14 53.7 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCU97773.1 - 0.0016 18.5 0.1 0.035 14.2 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CCU97773.1 - 0.015 15.2 0.2 0.049 13.5 0.2 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 FlpD PF02662.16 CCU97773.1 - 0.019 15.0 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit 5HT_transport_N PF03491.13 CCU97773.1 - 0.05 13.8 1.5 0.065 13.4 0.0 1.9 2 0 0 2 2 2 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus NIF3 PF01784.18 CCU97773.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) G-alpha PF00503.20 CCU97773.1 - 0.18 11.0 0.0 0.36 9.9 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit WH2 PF02205.20 CCU97774.1 - 0.001 18.8 0.1 0.0027 17.5 0.1 1.7 1 0 0 1 1 1 1 WH2 motif UQ_con PF00179.26 CCU97775.1 - 3e-47 159.8 0.0 3.4e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCU97775.1 - 7.9e-05 22.4 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CCU97775.1 - 0.0037 17.1 0.0 0.0071 16.2 0.0 1.6 1 1 0 1 1 1 1 UEV domain DUF2841 PF11001.8 CCU97776.1 - 6.8e-39 132.7 0.1 6.8e-39 132.7 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) His_Phos_1 PF00300.22 CCU97777.1 - 3.6e-39 134.5 0.0 4.1e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DNA_pol_B PF00136.21 CCU97778.1 - 3.1e-86 289.9 0.0 3.9e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CCU97778.1 - 4.6e-23 81.9 0.0 2.3e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CCU97778.1 - 3e-07 30.8 6.2 6.8e-07 29.7 6.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CCU97778.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral HEAT PF02985.22 CCU97779.1 - 5.7e-36 119.5 23.5 0.001 19.1 0.0 13.5 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.6 CCU97779.1 - 7.7e-32 109.5 21.6 1.5e-09 38.1 0.0 7.6 3 2 3 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.7 CCU97779.1 - 2.8e-13 50.3 1.1 0.00039 21.0 0.0 7.4 4 2 5 9 9 9 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CCU97779.1 - 1.8e-11 44.3 8.9 0.00029 20.9 0.1 5.2 4 2 1 5 5 5 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CCU97779.1 - 9.2e-11 42.0 27.8 0.0026 18.2 0.2 9.3 7 3 5 12 12 12 4 HEAT-like repeat Adaptin_N PF01602.20 CCU97779.1 - 2.8e-09 36.1 11.0 4.5e-07 28.8 3.9 3.7 2 1 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 CCU97779.1 - 2.9e-07 30.3 1.6 0.032 13.8 0.0 4.6 2 2 1 4 4 4 2 CLASP N terminal RTP1_C1 PF10363.9 CCU97779.1 - 0.0015 18.7 8.2 1.8 8.7 0.1 4.7 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF1804 PF08822.11 CCU97779.1 - 0.0027 17.7 1.2 0.62 10.0 0.0 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF1804) Arm PF00514.23 CCU97779.1 - 0.01 15.9 9.6 3.5 7.8 0.0 6.5 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.11 CCU97779.1 - 0.084 12.6 0.6 6.4 6.4 0.0 3.4 3 1 0 3 3 3 0 DNA alkylation repair enzyme CRAL_TRIO PF00650.20 CCU97780.1 - 5e-26 91.3 0.0 7.3e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CCU97780.1 - 6.5e-08 32.8 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SURF4 PF02077.15 CCU97781.1 - 4.4e-95 318.3 8.3 5e-95 318.1 8.3 1.0 1 0 0 1 1 1 1 SURF4 family NAT PF04768.13 CCU97782.1 - 7.5e-43 146.1 0.0 1.8e-42 144.9 0.0 1.6 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 CCU97782.1 - 9.6e-30 103.9 0.0 1.8e-29 103.0 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 CCU97782.1 - 3.6e-25 88.8 0.1 1.1e-24 87.2 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 CCU97782.1 - 1.1e-11 45.1 0.0 2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Pam16 PF03656.13 CCU97782.1 - 0.052 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Pam16 DapB_N PF01113.20 CCU97782.1 - 0.095 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pkinase PF00069.25 CCU97785.1 - 1.4e-67 227.8 0.0 1.7e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97785.1 - 5.2e-46 157.0 0.0 7.1e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU97785.1 - 6.1e-05 22.5 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CCU97785.1 - 0.00017 20.5 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CCU97785.1 - 0.0034 16.7 1.0 0.0064 15.9 1.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCU97785.1 - 0.0041 17.1 0.3 0.53 10.2 0.3 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CCU97785.1 - 0.023 13.6 0.3 0.064 12.2 0.3 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Raf1_N PF18578.1 CCU97785.1 - 0.11 13.0 0.1 0.21 12.1 0.1 1.6 1 1 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain Creatinase_N_2 PF16189.5 CCU97786.1 - 3.1e-47 160.7 0.0 5.7e-46 156.6 0.0 2.4 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CCU97786.1 - 1.7e-41 142.2 0.0 2.7e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 CCU97786.1 - 3.1e-26 91.2 0.0 8.5e-26 89.8 0.0 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CCU97786.1 - 2.5e-20 73.5 0.2 2.1e-17 64.0 0.0 3.2 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain AdoHcyase PF05221.17 CCU97787.1 - 7.1e-136 452.2 0.0 9.8e-75 251.5 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CCU97787.1 - 2.1e-83 278.3 1.8 3.1e-83 277.7 1.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CCU97787.1 - 2.1e-09 37.0 0.2 5e-09 35.8 0.1 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CCU97787.1 - 0.00029 20.5 0.1 0.00044 19.9 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CCU97787.1 - 0.002 18.4 0.1 0.0049 17.1 0.1 1.7 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.21 CCU97787.1 - 0.061 13.0 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 CCU97787.1 - 0.071 13.6 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding TPR_14 PF13428.6 CCU97788.1 - 0.027 15.3 3.4 5.6 8.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_2 PF13041.6 CCU97788.1 - 0.1 12.8 0.0 16 5.8 0.0 3.0 3 0 0 3 3 3 0 PPR repeat family EF-hand_7 PF13499.6 CCU97789.1 - 5.8e-25 87.5 7.9 3.3e-15 56.3 3.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CCU97789.1 - 1.1e-24 84.1 8.8 6.9e-09 34.6 0.2 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CCU97789.1 - 2.3e-20 70.7 9.5 1.1e-08 34.3 0.2 4.0 4 2 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CCU97789.1 - 1.1e-15 57.2 10.4 1.4e-09 37.6 1.5 3.3 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CCU97789.1 - 3.1e-13 48.6 6.6 5.1e-05 22.6 0.1 3.6 3 1 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 CCU97789.1 - 5e-10 39.6 0.5 0.00012 22.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CCU97789.1 - 8.8e-08 32.1 2.8 0.00014 21.7 0.2 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CCU97789.1 - 0.00013 21.9 0.3 0.043 13.8 0.0 3.0 2 1 1 3 3 3 1 Caleosin related protein EF-hand_14 PF17959.1 CCU97789.1 - 0.0053 17.1 1.7 0.23 11.8 0.4 2.4 1 1 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CCU97789.1 - 0.0071 16.7 0.9 1.2 9.5 0.1 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CCU97789.1 - 0.01 16.0 0.5 0.28 11.4 0.1 2.3 2 0 0 2 2 2 0 Dockerin type I domain PhetRS_B1 PF18262.1 CCU97789.1 - 0.028 14.6 1.3 0.076 13.2 1.3 1.7 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain SurA_N_2 PF13623.6 CCU97789.1 - 0.04 13.8 0.3 1.1 9.1 0.1 2.3 2 1 0 2 2 2 0 SurA N-terminal domain HTH_40 PF14493.6 CCU97789.1 - 0.065 13.7 0.1 4.5 7.8 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain DUF3164 PF11363.8 CCU97789.1 - 0.073 12.7 0.1 4 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3164) FANC_SAP PF18081.1 CCU97789.1 - 0.084 13.1 0.1 5.3 7.3 0.0 2.9 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain TFIIA_gamma_N PF02268.16 CCU97790.1 - 2e-25 88.5 0.1 2.9e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 CCU97790.1 - 3.8e-21 75.0 0.1 6.3e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Ctf8 PF09696.10 CCU97791.1 - 3.4e-12 46.9 0.6 1.5e-09 38.3 0.1 2.7 1 1 1 2 2 2 2 Ctf8 GalKase_gal_bdg PF10509.9 CCU97792.1 - 5.2e-20 70.7 0.1 1.3e-19 69.5 0.1 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 CCU97792.1 - 5.6e-15 55.5 0.0 1.3e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CCU97792.1 - 2.7e-12 46.7 0.4 8.3e-12 45.2 0.4 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF1845 PF08900.11 CCU97792.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) SLATT_6 PF18169.1 CCU97792.1 - 0.23 11.0 0.0 1 9.0 0.0 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 ArfGap PF01412.18 CCU97793.1 - 7.3e-29 100.2 0.2 1.1e-28 99.7 0.2 1.4 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 CCU97793.1 - 0.18 11.8 1.4 11 6.0 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger GATA PF00320.27 CCU97793.1 - 0.54 9.9 6.9 0.67 9.6 1.2 2.4 2 0 0 2 2 2 0 GATA zinc finger SANT_DAMP1_like PF16282.5 CCU97794.1 - 2.2e-30 104.7 2.9 2.2e-30 104.7 2.9 1.8 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 HCMV_UL139 PF12507.8 CCU97794.1 - 0.0019 18.6 2.3 0.0041 17.5 2.3 1.5 1 0 0 1 1 1 1 Human Cytomegalovirus UL139 protein Myb_DNA-binding PF00249.31 CCU97794.1 - 0.029 14.6 0.0 0.073 13.3 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Uso1_p115_C PF04871.13 CCU97794.1 - 0.17 12.3 4.8 0.16 12.4 0.8 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DFP PF04127.15 CCU97795.1 - 2e-19 70.2 0.0 5.3e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein zf-H2C2_2 PF13465.6 CCU97796.1 - 1.1e-08 35.1 0.6 1.1e-08 35.1 0.6 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 CCU97796.1 - 5e-08 33.0 16.6 7.3e-07 29.3 0.4 4.0 4 1 0 4 4 4 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 CCU97796.1 - 3.2e-05 24.5 15.3 0.021 15.5 0.3 4.4 3 1 2 5 5 5 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CCU97796.1 - 0.00066 20.3 14.7 0.0086 16.8 0.3 4.3 5 0 0 5 5 5 2 C2H2-type zinc finger zf-met PF12874.7 CCU97796.1 - 0.009 16.4 4.4 3.9 8.0 0.0 3.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CCU97796.1 - 0.036 14.1 4.3 0.061 13.3 0.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 CCU97796.1 - 0.51 10.7 3.3 3.9 7.8 0.3 2.8 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 CCU97796.1 - 1.1 9.5 6.4 6.3 7.0 0.0 3.5 2 2 1 3 3 3 0 Zic proteins zinc finger domain DnaJ PF00226.31 CCU97797.1 - 4.9e-13 49.0 0.2 1.1e-12 47.9 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Complex1_LYR PF05347.15 CCU97797.1 - 2.5e-06 27.4 0.0 2.5e-06 27.4 0.0 2.5 3 0 0 3 3 3 1 Complex 1 protein (LYR family) MMM1 PF10296.9 CCU97798.1 - 4.9e-37 127.7 0.0 2.7e-35 122.0 0.0 2.5 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 SPRY PF00622.28 CCU97799.1 - 1.4e-05 25.2 0.0 0.00048 20.2 0.0 2.2 2 0 0 2 2 2 1 SPRY domain Prp19 PF08606.11 CCU97799.1 - 0.067 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Prp19/Pso4-like Gtr1_RagA PF04670.12 CCU97800.1 - 9.2e-39 133.2 0.2 3.2e-37 128.1 0.2 2.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SUI1 PF01253.22 CCU97800.1 - 0.0001 22.8 0.8 0.0016 18.9 0.8 2.4 1 1 0 1 1 1 1 Translation initiation factor SUI1 MMR_HSR1 PF01926.23 CCU97800.1 - 0.00047 20.2 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CCU97800.1 - 0.0015 18.9 0.1 0.3 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 CCU97800.1 - 0.0032 17.7 0.0 0.0092 16.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 CCU97800.1 - 0.0092 16.0 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arf PF00025.21 CCU97800.1 - 0.031 13.7 0.1 5.9 6.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Cgr1 PF03879.14 CCU97800.1 - 0.047 14.1 10.7 0.08 13.3 10.7 1.3 1 0 0 1 1 1 0 Cgr1 family Guanylate_kin PF00625.21 CCU97800.1 - 0.057 13.1 0.8 7 6.3 0.4 2.4 2 0 0 2 2 2 0 Guanylate kinase Ras PF00071.22 CCU97800.1 - 0.064 12.8 0.1 0.54 9.8 0.1 2.2 1 1 0 1 1 1 0 Ras family GTP_EFTU PF00009.27 CCU97800.1 - 0.11 12.0 1.5 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ras PF00071.22 CCU97801.1 - 7.5e-45 152.4 0.0 9.5e-45 152.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCU97801.1 - 1.1e-18 67.6 0.0 1.8e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU97801.1 - 5.5e-08 32.5 0.0 6.7e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCU97801.1 - 0.00024 20.7 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CCU97801.1 - 0.04 13.3 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 CCU97801.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Glyco_hydro_75 PF07335.11 CCU97801.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 EF_TS PF00889.19 CCU97802.1 - 4.1e-12 46.1 0.0 1.4e-11 44.5 0.0 1.9 2 1 0 2 2 2 1 Elongation factor TS Nucleoporin_N PF08801.11 CCU97803.1 - 4.8e-39 134.3 0.0 6.8e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 CCU97803.1 - 6.5e-26 91.2 0.7 9.7e-26 90.6 0.7 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal LCM PF04072.14 CCU97804.1 - 1.3e-09 38.2 0.1 6.4e-09 36.0 0.1 2.1 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Fcf1 PF04900.12 CCU97805.1 - 6.2e-30 103.5 0.0 1e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Fcf1 SE PF08491.10 CCU97806.1 - 1.6e-86 289.8 0.0 1.1e-85 287.0 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 CCU97806.1 - 2.4e-10 40.2 1.9 8.4e-09 35.1 1.9 2.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 CCU97806.1 - 8.9e-09 35.4 2.0 0.00014 21.5 0.5 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCU97806.1 - 0.00087 19.5 1.1 0.0021 18.2 1.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CCU97806.1 - 0.0012 18.2 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCU97806.1 - 0.0053 15.9 0.1 0.27 10.3 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 CCU97806.1 - 0.0081 15.4 0.2 0.041 13.1 0.1 1.9 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.18 CCU97806.1 - 0.023 14.6 0.1 0.042 13.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 CCU97806.1 - 0.024 14.5 0.2 0.075 12.9 0.2 1.8 1 0 0 1 1 1 0 Rossmann-like domain Shikimate_DH PF01488.20 CCU97806.1 - 0.025 14.6 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 CCU97806.1 - 0.03 14.9 0.5 0.061 13.9 0.5 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 CCU97806.1 - 0.042 13.5 0.1 0.085 12.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 CCU97806.1 - 0.044 13.1 1.5 0.067 12.5 1.1 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CCU97806.1 - 0.14 11.2 5.9 0.036 13.2 2.6 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_2 PF03446.15 CCU97806.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 CCU97806.1 - 0.15 11.6 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 CCU97806.1 - 0.16 10.6 0.1 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 CCU97806.1 - 0.18 12.0 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain ATP-synt_J PF04911.12 CCU97807.1 - 8e-22 76.6 0.3 1.1e-21 76.1 0.3 1.2 1 0 0 1 1 1 1 ATP synthase j chain AMP-binding PF00501.28 CCU97808.1 - 4.4e-67 226.5 0.0 7.9e-67 225.7 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCU97808.1 - 0.018 16.0 0.1 0.059 14.4 0.1 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain SAGA-Tad1 PF12767.7 CCU97808.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Clathrin PF00637.20 CCU97809.1 - 1.8e-15 57.1 0.0 1.8e-12 47.4 0.0 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 CCU97809.1 - 3.1e-05 23.9 4.5 6.9e-05 22.8 4.5 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 CCU97809.1 - 5.9e-05 22.8 6.0 0.00013 21.8 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) VPS11_C PF12451.8 CCU97809.1 - 0.00019 21.6 0.1 0.00036 20.7 0.1 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.6 CCU97809.1 - 0.0008 19.7 5.6 0.002 18.4 5.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CCU97809.1 - 0.013 15.4 4.7 0.031 14.2 4.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 CCU97809.1 - 0.013 15.7 4.4 0.043 14.1 4.4 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CCU97809.1 - 0.054 13.5 3.8 0.12 12.4 3.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Vps39_2 PF10367.9 CCU97809.1 - 0.065 13.7 0.1 0.22 12.0 0.1 2.0 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.25 CCU97809.1 - 0.53 10.2 5.0 1.2 9.0 5.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCU97809.1 - 1.7 8.5 3.8 4.4 7.1 3.8 1.8 1 0 0 1 1 1 0 RING-like zinc finger DUF1180 PF06679.12 CCU97810.1 - 0.0042 17.5 4.5 0.0068 16.8 4.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Pheromone PF08015.11 CCU97810.1 - 0.28 12.2 4.8 0.75 10.9 4.8 1.7 1 0 0 1 1 1 0 Fungal mating-type pheromone TT_ORF2 PF02957.15 CCU97810.1 - 0.36 11.7 1.3 0.6 11.0 1.3 1.3 1 0 0 1 1 1 0 TT viral ORF2 Ras PF00071.22 CCU97811.1 - 4.2e-40 137.0 1.0 4.9e-40 136.8 1.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCU97811.1 - 4e-15 56.1 1.1 4.4e-15 55.9 0.3 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU97811.1 - 1.8e-06 27.5 0.4 2.2e-06 27.3 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Phage_C PF12025.8 CCU97811.1 - 0.053 13.4 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage protein C GTP_EFTU PF00009.27 CCU97811.1 - 0.064 12.8 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ATP-synt_10 PF05176.14 CCU97812.1 - 3.8e-27 95.2 0.0 8.5e-18 64.5 0.0 3.0 1 1 2 3 3 3 2 ATP10 protein U3_assoc_6 PF08640.11 CCU97812.1 - 2.9e-16 59.3 3.0 9.4e-16 57.7 2.1 2.2 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 DNA_primase_lrg PF04104.14 CCU97813.1 - 2.3e-77 260.0 0.0 3.1e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit PIP5K PF01504.18 CCU97814.1 - 5.9e-90 301.2 0.0 1.2e-89 300.2 0.0 1.4 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase His_biosynth PF00977.21 CCU97816.1 - 3e-42 144.7 0.0 1e-24 87.3 0.1 3.1 2 2 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.28 CCU97816.1 - 4.5e-13 49.4 0.0 7.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 CCU97816.1 - 2.9e-06 27.0 0.0 8.4e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 CCU97816.1 - 0.00013 21.9 0.0 0.061 13.2 0.0 2.5 2 0 0 2 2 2 2 SNO glutamine amidotransferase family PhoD PF09423.10 CCU97817.1 - 3e-29 102.2 0.0 7.9e-29 100.8 0.0 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 CCU97817.1 - 0.017 15.7 0.0 0.4 11.3 0.0 2.3 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 CCU97817.1 - 0.46 11.1 1.8 0.65 10.6 0.5 1.9 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain Ribosomal_S7 PF00177.21 CCU97818.1 - 7e-33 113.4 0.0 8.2e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Response_reg PF00072.24 CCU97819.1 - 5.8e-16 58.7 0.0 6.3e-15 55.3 0.0 2.3 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 CCU97819.1 - 5.5e-15 55.2 1.0 1.7e-14 53.6 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain TFIIB PF00382.19 CCU97820.1 - 9.7e-30 102.4 5.6 1.7e-17 63.2 0.7 2.9 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CCU97820.1 - 3e-15 55.5 1.0 5e-15 54.7 1.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 CCU97820.1 - 0.00023 21.2 0.1 0.00054 20.0 0.1 1.6 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 CCU97820.1 - 0.0097 16.0 0.0 4.2 7.5 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain GP57 PF17594.2 CCU97820.1 - 0.11 12.2 0.1 0.98 9.2 0.0 2.6 2 1 1 3 3 3 0 Phage Tail fiber assembly helper gene product 57 SpoIIID PF12116.8 CCU97820.1 - 0.11 12.6 0.3 0.31 11.2 0.3 1.7 1 0 0 1 1 1 0 Stage III sporulation protein D Nudix_N_2 PF14803.6 CCU97820.1 - 1.2 9.2 3.6 21 5.1 0.1 3.4 3 0 0 3 3 3 0 Nudix N-terminal Nup84_Nup100 PF04121.13 CCU97821.1 - 3.2e-139 465.3 0.0 6.7e-138 460.9 0.0 2.0 1 1 1 2 2 2 2 Nuclear pore protein 84 / 107 DciA PF05258.12 CCU97821.1 - 0.041 14.3 0.8 0.16 12.4 0.8 2.0 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA SH3_1 PF00018.28 CCU97823.1 - 5.1e-11 42.0 0.0 9.5e-11 41.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCU97823.1 - 1.4e-09 37.7 0.1 2.6e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCU97823.1 - 2.6e-08 33.4 0.0 5.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF2397 PF09660.10 CCU97823.1 - 0.043 12.7 4.8 0.066 12.1 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) SHE3 PF17078.5 CCU97823.1 - 0.044 13.5 6.1 0.35 10.6 1.1 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 GCN5L1 PF06320.13 CCU97823.1 - 0.89 9.7 5.3 0.71 10.0 3.3 1.8 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) OmpH PF03938.14 CCU97823.1 - 1.1 9.6 6.6 0.69 10.3 0.8 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 CCU97823.1 - 1.1 9.3 10.0 1.6 8.8 9.2 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 CCU97823.1 - 1.6 8.0 6.0 2.4 7.4 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FCH PF00611.23 CCU97824.1 - 0.0076 16.5 0.0 0.0097 16.2 0.0 1.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain PCNA_N PF00705.18 CCU97825.1 - 1.3e-50 170.4 1.6 7.3e-50 167.9 2.1 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CCU97825.1 - 1.7e-40 138.2 2.4 1.3e-21 77.1 0.0 3.0 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 CCU97825.1 - 2.1e-05 24.1 0.0 0.00019 20.9 0.0 2.1 1 1 0 1 1 1 1 Rad9 Rad1 PF02144.16 CCU97825.1 - 9.1e-05 21.6 0.7 0.041 13.0 0.3 2.1 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 CCU97825.1 - 0.0065 15.6 0.0 0.1 11.7 0.0 2.1 1 1 0 2 2 2 1 Hus1-like protein RTA1 PF04479.13 CCU97826.1 - 4.4e-54 183.2 3.6 4.4e-54 183.2 3.6 1.7 1 1 1 2 2 2 1 RTA1 like protein SLAC1 PF03595.17 CCU97826.1 - 0.0015 17.9 17.4 0.0037 16.6 17.4 1.6 1 1 0 1 1 1 1 Voltage-dependent anion channel HlyIII PF03006.20 CCU97826.1 - 0.092 12.4 10.5 1.2 8.8 10.5 2.3 1 1 0 1 1 1 0 Haemolysin-III related SET PF00856.28 CCU97827.1 - 7.1e-05 23.3 0.2 0.003 17.9 0.0 2.9 2 1 0 2 2 2 1 SET domain TPR_10 PF13374.6 CCU97827.1 - 0.037 13.9 0.4 1.4 8.9 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 CCU97827.1 - 0.078 13.6 0.1 0.078 13.6 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCU97827.1 - 0.15 12.7 0.1 0.15 12.7 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CCU97827.1 - 5.3 8.1 10.8 2.3 9.3 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_S8 PF00082.22 CCU97828.1 - 3.6e-66 223.5 0.6 6.5e-66 222.6 0.6 1.4 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 CCU97828.1 - 1.3e-48 165.0 0.0 3.1e-48 163.8 0.0 1.6 2 0 0 2 2 2 1 Tripeptidyl peptidase II GAS PF13851.6 CCU97828.1 - 0.4 10.0 4.9 0.74 9.1 4.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GDI PF00996.18 CCU97829.1 - 8.4e-39 133.3 0.0 1.1e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CCU97829.1 - 0.0026 17.9 0.1 0.0061 16.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CCU97829.1 - 0.019 14.2 0.1 0.052 12.8 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Peptidase_S49 PF01343.18 CCU97830.1 - 1.4e-45 155.0 0.0 1.6e-27 96.3 0.1 3.1 3 0 0 3 3 3 2 Peptidase family S49 CLP_protease PF00574.23 CCU97830.1 - 0.0013 18.6 0.1 0.047 13.6 0.0 2.4 2 0 0 2 2 2 1 Clp protease DPBB_1 PF03330.18 CCU97831.1 - 8.6e-09 35.6 0.1 1.1e-08 35.2 0.1 1.3 1 0 0 1 1 1 1 Lytic transglycolase Chordopox_A13L PF05961.11 CCU97831.1 - 0.056 13.7 0.2 0.12 12.6 0.1 1.5 2 0 0 2 2 2 0 Chordopoxvirus A13L protein TRAM_LAG1_CLN8 PF03798.16 CCU97832.1 - 3e-38 131.5 18.6 3e-38 131.5 18.6 2.2 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CCU97832.1 - 4.3e-06 26.3 0.0 4.3e-06 26.3 0.0 3.2 3 0 0 3 3 3 2 TRAM1-like protein Aldedh PF00171.22 CCU97833.1 - 5.7e-09 35.0 4.4 5.3e-08 31.8 4.4 2.1 1 1 0 1 1 1 1 Aldehyde dehydrogenase family RlaP PF10127.9 CCU97833.1 - 0.76 9.3 2.6 2 7.9 0.8 2.1 2 0 0 2 2 2 0 RNA repair pathway DNA polymerase beta family DUF3636 PF12331.8 CCU97834.1 - 0.0025 17.6 0.9 2.2 8.1 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3636) Ipi1_N PF12333.8 CCU97834.1 - 0.074 13.6 0.5 2.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation XPG_N PF00752.17 CCU97835.1 - 1.8e-19 70.1 0.0 2.1e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 XPG N-terminal domain Peripla_BP_2 PF01497.18 CCU97835.1 - 0.085 12.4 0.0 0.096 12.2 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein XPG_I PF00867.18 CCU97836.1 - 1.4e-14 54.2 0.0 2.6e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CCU97836.1 - 9e-07 29.4 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.11 CCU97836.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) HHH_5 PF14520.6 CCU97836.1 - 0.037 14.6 0.0 0.07 13.7 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain SKN1 PF03935.15 CCU97837.1 - 0 1144.9 19.1 3.9e-173 576.5 7.8 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2162 PF09930.9 CCU97837.1 - 0.0018 17.7 0.0 0.44 9.9 0.0 2.1 2 0 0 2 2 2 2 Predicted transporter (DUF2162) zf-C2H2 PF00096.26 CCU97838.1 - 1.4e-12 47.3 15.5 1.2e-05 25.4 0.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCU97838.1 - 1.7e-10 40.8 14.7 0.0028 18.4 0.4 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCU97838.1 - 2.1e-07 30.8 1.6 0.00051 20.0 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCU97838.1 - 0.0026 18.1 13.2 0.21 12.1 0.3 4.4 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCU97838.1 - 0.0071 16.6 1.1 10 6.5 0.2 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zinc_ribbon_4 PF13717.6 CCU97838.1 - 0.11 12.5 0.9 16 5.5 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L37ae PF01780.19 CCU97838.1 - 0.11 12.5 1.2 0.73 10.0 0.2 2.3 2 0 0 2 2 2 0 Ribosomal L37ae protein family Elf1 PF05129.13 CCU97838.1 - 0.24 11.5 1.1 1.1 9.3 0.3 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like TRAF6_Z2 PF18048.1 CCU97838.1 - 0.26 11.4 1.7 0.6 10.3 0.1 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2HE PF16278.5 CCU97838.1 - 0.28 11.6 2.4 2.6 8.6 0.1 2.9 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger RNHCP PF12647.7 CCU97838.1 - 0.36 10.8 1.6 1.7 8.6 0.3 2.3 2 0 0 2 2 2 0 RNHCP domain Zn-ribbon_8 PF09723.10 CCU97838.1 - 1.2 9.4 4.5 4.7 7.4 0.8 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 CCU97838.1 - 3.3 7.5 14.7 6.1 6.7 2.9 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type FYVE PF01363.21 CCU97838.1 - 5.4 7.2 7.2 2.6 8.3 1.6 2.3 2 0 0 2 2 2 0 FYVE zinc finger SET PF00856.28 CCU97839.1 - 0.0032 17.9 0.9 0.012 16.1 0.9 1.8 1 1 0 1 1 1 1 SET domain NOA36 PF06524.12 CCU97839.1 - 0.79 9.0 5.9 1.1 8.5 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein Steroid_dh PF02544.16 CCU97840.1 - 1.5e-38 132.2 0.2 1.5e-38 132.2 0.2 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CCU97840.1 - 0.0001 21.9 0.2 0.00022 20.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 CCU97840.1 - 0.0012 19.2 1.3 0.0029 18.0 0.1 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase MarC PF01914.17 CCU97840.1 - 0.0073 15.7 0.0 0.021 14.2 0.0 1.8 1 1 1 2 2 2 1 MarC family integral membrane protein ICMT PF04140.14 CCU97840.1 - 0.0094 16.4 0.3 0.03 14.7 0.3 1.9 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Skp1_POZ PF03931.15 CCU97842.1 - 1.2e-07 31.8 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain ATP-synt_C PF00137.21 CCU97843.1 - 2.6e-21 75.7 15.2 6.5e-11 42.4 4.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Peptidase_C13 PF01650.18 CCU97844.1 - 7.8e-47 159.9 0.0 9.3e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 CCU97844.1 - 0.018 15.3 0.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 Mid domain of argonaute DS PF01916.17 CCU97845.1 - 8.2e-131 435.5 0.0 1.1e-130 435.0 0.0 1.2 1 0 0 1 1 1 1 Deoxyhypusine synthase ThiF PF00899.21 CCU97845.1 - 5.4e-64 215.9 0.0 1.2e-63 214.7 0.0 1.5 1 0 0 1 1 1 1 ThiF family PIG-S PF10510.9 CCU97845.1 - 0.063 12.1 0.2 0.09 11.6 0.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein UBA_e1_thiolCys PF10585.9 CCU97845.1 - 0.14 12.1 0.1 4.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Ecm33 PF12454.8 CCU97845.1 - 0.35 11.1 1.9 0.74 10.0 1.9 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein G-patch PF01585.23 CCU97847.1 - 2e-12 46.8 1.4 4.9e-12 45.5 1.4 1.7 1 0 0 1 1 1 1 G-patch domain R3H PF01424.22 CCU97847.1 - 1.1e-11 44.6 0.1 3.2e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 R3H domain G-patch_2 PF12656.7 CCU97847.1 - 3.8e-06 26.9 1.0 3.8e-06 26.9 1.0 2.5 2 0 0 2 2 2 1 G-patch domain SIR2 PF02146.17 CCU97848.1 - 1.6e-51 174.8 0.0 2.4e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 CCU97848.1 - 1.8e-06 27.8 0.1 1e-05 25.4 0.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF592) CutC PF03932.14 CCU97848.1 - 0.017 14.6 0.0 0.068 12.6 0.0 1.8 2 0 0 2 2 2 0 CutC family SpdB PF05122.13 CCU97848.1 - 0.15 12.3 1.1 0.31 11.2 1.1 1.5 1 0 0 1 1 1 0 Mobile element transfer protein DUF1769 PF08588.10 CCU97849.1 - 4e-14 52.5 0.6 7.4e-14 51.7 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) SURF6 PF04935.12 CCU97850.1 - 8.6e-28 97.5 18.6 1.1e-27 97.1 18.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 6 SpoVR PF04293.13 CCU97850.1 - 1.4 7.5 6.5 1.5 7.4 6.0 1.2 1 1 0 1 1 1 0 SpoVR like protein betaPIX_CC PF16523.5 CCU97850.1 - 3.9 7.4 10.9 0.19 11.5 4.5 2.1 2 1 0 2 2 2 0 betaPIX coiled coil TarH PF02203.15 CCU97850.1 - 4.6 7.1 10.1 4.9 7.0 9.5 1.4 1 1 0 1 1 1 0 Tar ligand binding domain homologue WD40 PF00400.32 CCU97851.1 - 3.9e-66 217.4 24.1 7.4e-11 42.4 0.3 9.2 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU97851.1 - 4.6e-22 78.1 1.3 0.00011 22.4 0.0 5.4 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCU97851.1 - 9.4e-07 28.1 0.1 0.45 9.4 0.0 4.2 3 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein NLE PF08154.12 CCU97851.1 - 3.6e-06 27.4 0.0 7.5e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 NLE (NUC135) domain IKI3 PF04762.12 CCU97851.1 - 0.00042 18.5 1.7 0.0011 17.0 0.1 1.9 2 0 0 2 2 2 1 IKI3 family eIF2A PF08662.11 CCU97851.1 - 0.00059 19.8 0.1 0.02 14.8 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CCU97851.1 - 0.00062 18.5 6.6 1.4 7.5 0.2 4.7 5 1 0 6 6 6 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 CCU97851.1 - 0.0018 17.7 0.2 1.5 8.1 0.1 3.3 2 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 CCU97851.1 - 0.097 12.0 0.0 6.2 6.1 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain PD40 PF07676.12 CCU97851.1 - 0.17 11.9 0.7 2.7 8.1 0.2 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 CCU97851.1 - 0.33 9.7 0.6 35 3.0 0.0 3.1 2 1 1 3 3 3 0 Nup133 N terminal like UQ_con PF00179.26 CCU97852.1 - 3.1e-22 78.7 0.0 2.5e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme BRO1 PF03097.18 CCU97854.1 - 4.2e-65 220.1 0.0 8.1e-65 219.1 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CCU97854.1 - 6.9e-26 91.2 8.4 1.3e-25 90.4 5.5 2.0 1 1 1 2 2 2 1 ALIX V-shaped domain binding to HIV UvrD_C PF13361.6 CCU97854.1 - 0.064 12.6 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF3730 PF12530.8 CCU97854.1 - 0.095 12.3 1.8 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) MAGSP PF03082.14 CCU97854.1 - 0.11 12.0 0.2 0.2 11.2 0.2 1.3 1 0 0 1 1 1 0 Male accessory gland secretory protein Yuri_gagarin PF15934.5 CCU97854.1 - 2 8.2 7.8 4.6 7.0 7.8 1.6 1 0 0 1 1 1 0 Yuri gagarin WGG PF10273.9 CCU97855.1 - 4.2e-18 65.8 0.0 6.4e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF3425 PF11905.8 CCU97855.1 - 0.0077 16.2 0.0 0.0079 16.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.25 CCU97856.1 - 1.1e-53 181.6 1.2 1.6e-53 181.1 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCU97856.1 - 1.6e-35 122.8 1.3 2e-35 122.4 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCU97856.1 - 2.5e-11 43.8 0.9 3e-11 43.5 0.9 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CCU97856.1 - 0.0022 17.9 3.5 0.011 15.6 3.5 2.2 1 1 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 CCU97856.1 - 0.014 14.7 0.1 0.035 13.4 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 CCU97856.1 - 0.023 14.1 0.7 0.059 12.8 0.7 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 CCU97856.1 - 0.043 13.7 0.1 0.074 12.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CCU97856.1 - 0.089 12.1 0.1 0.2 11.0 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 CCU97856.1 - 0.097 12.4 0.3 0.2 11.5 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase COG4 PF08318.12 CCU97857.1 - 5.8e-32 111.1 0.0 1.6e-31 109.7 0.0 1.7 1 1 0 1 1 1 1 COG4 transport protein DUF1844 PF08899.11 CCU97857.1 - 0.071 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) Snf7 PF03357.21 CCU97858.1 - 0.11 12.1 0.4 0.45 10.1 0.2 1.9 2 0 0 2 2 2 0 Snf7 APS_kinase PF01583.20 CCU97859.1 - 3.8e-65 218.6 0.0 9.3e-65 217.3 0.0 1.6 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 CCU97859.1 - 1.3e-05 25.4 0.0 2.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCU97859.1 - 8.8e-05 23.1 0.0 0.00014 22.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 CCU97859.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 CCU97859.1 - 0.0023 17.6 0.1 0.0042 16.8 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CCU97859.1 - 0.0044 16.3 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF463 PF04317.12 CCU97859.1 - 0.027 13.4 0.1 0.039 12.9 0.1 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 ABC_tran PF00005.27 CCU97859.1 - 0.036 14.6 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CCU97859.1 - 0.085 13.2 0.1 0.14 12.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain Cytidylate_kin PF02224.18 CCU97859.1 - 0.099 12.4 0.0 6.4 6.4 0.0 2.8 3 0 0 3 3 3 0 Cytidylate kinase PRK PF00485.18 CCU97859.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 CCU97859.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 CCU97859.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein 6PF2K PF01591.18 CCU97859.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase YabA PF06156.13 CCU97860.1 - 0.11 13.1 0.4 0.13 12.9 0.4 1.2 1 1 0 1 1 1 0 Initiation control protein YabA AAA PF00004.29 CCU97863.1 - 1.3e-95 316.9 0.0 2.6e-46 157.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCU97863.1 - 7.3e-28 96.1 3.7 1.7e-13 50.1 0.2 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 CCU97863.1 - 3.7e-15 55.8 0.1 1.2e-14 54.2 0.1 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CCU97863.1 - 5.4e-14 52.2 0.1 1.4e-05 24.9 0.0 3.4 2 2 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CCU97863.1 - 2.2e-12 47.4 0.0 2.9e-07 30.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CCU97863.1 - 8.3e-12 45.5 0.0 6.2e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 CCU97863.1 - 1e-11 44.5 0.0 2.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 CCU97863.1 - 5e-11 42.7 0.7 3.6e-05 23.8 0.1 3.3 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCU97863.1 - 9.8e-11 42.3 0.0 0.00076 19.9 0.0 4.3 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 CCU97863.1 - 3.5e-09 36.3 0.1 0.0018 17.5 0.0 2.5 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 CCU97863.1 - 3.7e-09 37.0 0.3 0.047 14.0 0.0 4.2 3 2 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 CCU97863.1 - 1.8e-07 31.0 0.0 0.01 15.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 CCU97863.1 - 4.3e-07 29.5 0.4 0.026 13.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CCU97863.1 - 8.5e-07 29.6 0.0 0.034 14.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 CCU97863.1 - 1.2e-06 28.6 0.0 0.0099 15.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CCU97863.1 - 1.4e-06 28.6 0.0 0.022 15.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ATPase PF06745.13 CCU97863.1 - 1.7e-06 27.6 0.3 0.56 9.5 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 CCU97863.1 - 2e-06 27.4 0.1 0.027 14.0 0.0 3.0 2 1 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 CCU97863.1 - 3.6e-06 26.9 0.4 5.1e-05 23.2 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.17 CCU97863.1 - 4.9e-06 25.8 0.1 0.0055 15.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CCU97863.1 - 5.1e-06 26.2 3.7 0.3 10.6 0.1 4.5 3 2 2 5 5 5 1 AAA domain ABC_tran PF00005.27 CCU97863.1 - 6.2e-06 26.8 0.0 0.049 14.1 0.0 3.3 2 1 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 CCU97863.1 - 1.3e-05 25.5 0.0 0.19 12.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 CCU97863.1 - 1.6e-05 24.6 0.0 0.38 10.4 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.16 CCU97863.1 - 4.3e-05 23.1 0.1 0.36 10.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.6 CCU97863.1 - 5.2e-05 23.1 0.0 0.48 10.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 CCU97863.1 - 8.3e-05 21.9 0.0 0.03 13.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.6 CCU97863.1 - 0.00016 22.1 0.0 0.62 10.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain Bac_DnaA PF00308.18 CCU97863.1 - 0.00016 21.6 0.0 0.4 10.5 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein TsaE PF02367.17 CCU97863.1 - 0.00022 21.2 0.0 0.24 11.4 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 CCU97863.1 - 0.00025 21.1 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 CCU97863.1 - 0.00035 20.5 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 CCU97863.1 - 0.00067 19.5 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 CCU97863.1 - 0.00074 18.9 0.7 0.47 9.6 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 CCU97863.1 - 0.0011 19.1 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 CCU97863.1 - 0.0011 18.9 0.2 0.68 9.8 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 CCU97863.1 - 0.0018 18.0 0.4 2.2 8.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CCU97863.1 - 0.0039 17.5 1.4 2.6 8.4 0.0 3.2 2 1 1 3 3 3 1 AAA domain ATPase_2 PF01637.18 CCU97863.1 - 0.005 16.8 0.1 11 5.9 0.0 3.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CCU97863.1 - 0.0055 16.0 0.0 3.4 6.9 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Viral_helicase1 PF01443.18 CCU97863.1 - 0.0071 16.1 0.0 0.5 10.1 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 CCU97863.1 - 0.014 14.6 0.0 0.84 8.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 CCU97863.1 - 0.033 14.1 0.4 6.5 6.6 0.0 3.4 3 0 0 3 3 3 0 NTPase IPT PF01745.16 CCU97863.1 - 0.037 13.4 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase T2SSE PF00437.20 CCU97863.1 - 0.054 12.5 0.0 0.97 8.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 CCU97863.1 - 0.058 13.1 0.0 8.7 6.0 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase KAP_NTPase PF07693.14 CCU97863.1 - 0.064 12.5 0.0 0.67 9.1 0.0 2.4 2 1 0 3 3 3 0 KAP family P-loop domain Zot PF05707.12 CCU97863.1 - 0.16 11.6 0.1 15 5.2 0.0 3.0 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_6 PF12774.7 CCU97863.1 - 0.21 10.5 0.1 7.9 5.3 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region HSP70 PF00012.20 CCU97864.1 - 8.6e-155 516.3 0.0 2.6e-154 514.7 0.0 1.6 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CCU97864.1 - 2.1e-06 26.8 0.0 3.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Ribosomal_L30_N PF08079.12 CCU97865.1 - 8.5e-28 96.4 14.3 1.6e-27 95.6 14.3 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CCU97865.1 - 3.2e-17 62.1 0.6 3.2e-17 62.1 0.6 2.4 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e PX PF00787.24 CCU97866.1 - 3.4e-26 91.5 0.1 4.9e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 PX domain SIR2 PF02146.17 CCU97868.1 - 2.2e-06 27.7 0.0 4.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Sir2 family V-SNARE_C PF12352.8 CCU97869.1 - 1.4e-13 50.9 0.8 3.1e-13 49.8 0.8 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Syntaxin-18_N PF10496.9 CCU97869.1 - 0.005 17.1 0.2 0.23 11.7 0.0 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Talin_middle PF09141.10 CCU97869.1 - 0.08 13.0 4.1 5.4 7.0 1.8 2.2 2 0 0 2 2 2 0 Talin, middle domain Methyltransf_25 PF13649.6 CCU97870.1 - 2e-11 44.4 0.0 4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CCU97870.1 - 2.8e-10 40.1 0.1 3.6e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CCU97870.1 - 1.3e-09 38.1 0.0 2.4e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCU97870.1 - 1.3e-08 34.9 0.0 4.8e-08 33.0 0.0 1.8 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCU97870.1 - 1.3e-08 35.4 0.0 2.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCU97870.1 - 7.9e-06 26.5 0.0 1.6e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CCU97870.1 - 2.4e-05 23.4 0.1 3.9e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 CCU97870.1 - 0.00011 21.8 0.1 0.00019 21.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 CCU97870.1 - 0.00014 21.2 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 CCU97870.1 - 0.0057 16.8 0.3 0.013 15.6 0.3 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 CCU97870.1 - 0.007 16.3 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CCU97870.1 - 0.0078 16.0 0.1 0.015 15.1 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 CCU97870.1 - 0.021 14.6 0.1 0.031 14.0 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 CCU97870.1 - 0.068 14.2 0.0 0.14 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 CCU97870.1 - 0.1 12.0 0.4 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 CCU97870.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 CCU97870.1 - 0.16 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 CCU97870.1 - 0.27 11.0 0.9 0.64 9.7 0.3 1.8 1 1 0 2 2 2 0 Met-10+ like-protein CTP_transf_1 PF01148.20 CCU97871.1 - 2.3e-70 237.4 17.2 7.5e-65 219.3 11.7 2.2 2 0 0 2 2 2 2 Cytidylyltransferase family DUF2953 PF11167.8 CCU97871.1 - 0.0056 16.7 1.6 0.011 15.7 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2953) DUF737 PF05300.11 CCU97871.1 - 8.9 6.6 11.0 14 6.0 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) MFS_1 PF07690.16 CCU97874.1 - 2.6e-40 138.5 49.3 1.1e-39 136.4 48.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCU97874.1 - 1.4e-12 47.2 14.6 1.4e-12 47.2 14.6 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CCU97874.1 - 1.4e-08 33.7 15.0 2.3e-08 33.0 15.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CIAPIN1 PF05093.13 CCU97875.1 - 4.4e-32 110.6 3.2 8.4e-32 109.7 3.2 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 CCU97875.1 - 1.8e-07 31.4 0.0 2.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus PRCC PF10253.9 CCU97876.1 - 5.1e-13 50.3 14.9 5.1e-13 50.3 14.9 2.4 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Lsm_interact PF05391.11 CCU97876.1 - 0.64 9.6 0.0 0.64 9.6 0.0 2.4 2 0 0 2 2 2 0 Lsm interaction motif EMP24_GP25L PF01105.24 CCU97877.1 - 3.8e-27 95.4 0.0 4.9e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ran_BP1 PF00638.18 CCU97878.1 - 1.7e-13 50.9 0.0 2.8e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Lig_C PF18330.1 CCU97878.1 - 0.034 14.2 0.0 0.042 13.8 0.0 1.1 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Tau95 PF09734.9 CCU97879.1 - 2e-28 100.0 0.1 4.9e-28 98.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CCU97879.1 - 5.2e-20 71.9 0.0 1e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain DNA_pol_E_B PF04042.16 CCU97880.1 - 2.6e-15 56.4 1.2 1.2e-14 54.1 1.2 1.9 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 CCU97880.1 - 4.1e-15 56.4 0.0 6.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Tuberculin PF12198.8 CCU97880.1 - 0.023 14.8 0.1 0.56 10.3 0.1 2.4 2 0 0 2 2 2 0 Theoretical tuberculin protein Nop PF01798.18 CCU97881.1 - 3.6e-83 278.6 0.1 3.6e-83 278.6 0.1 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CCU97881.1 - 4.5e-17 62.2 0.2 4.5e-17 62.2 0.2 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 CCU97881.1 - 0.83 9.7 40.4 1.5 8.9 40.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 CCU97881.1 - 1 9.2 18.3 1.5 8.5 18.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.7 CCU97881.1 - 1.3 9.3 20.5 2.5 8.4 19.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) GAGA_bind PF06217.12 CCU97881.1 - 2.6 8.2 14.0 3.7 7.7 14.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_pol_Rpc4 PF05132.14 CCU97881.1 - 8.7 6.8 17.3 17 5.8 17.3 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Rhodanese PF00581.20 CCU97882.1 - 6.3e-11 42.7 0.0 8.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain YqjK PF13997.6 CCU97882.1 - 0.096 12.9 0.1 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 YqjK-like protein PT PF04886.12 CCU97883.1 - 3.3e-06 26.5 20.0 3.3e-06 26.5 20.0 3.5 2 1 1 3 3 3 1 PT repeat DUF572 PF04502.13 CCU97883.1 - 0.21 11.2 10.0 0.37 10.4 10.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOG2 PF10428.9 CCU97883.1 - 1.7 7.7 13.9 2.4 7.2 13.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein TP2 PF01254.18 CCU97883.1 - 2.1 9.0 12.1 0.079 13.6 5.6 2.1 2 0 0 2 2 2 0 Nuclear transition protein 2 PS_Dcarbxylase PF02666.15 CCU97884.1 - 3.6e-68 229.1 0.0 8.9e-52 175.5 0.0 2.2 1 1 0 2 2 2 2 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 CCU97884.1 - 0.018 14.7 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 MNLL subunit Nup88 PF10168.9 CCU97885.1 - 2.8e-28 98.2 0.1 1.8e-13 49.3 2.2 2.7 2 1 0 2 2 2 2 Nuclear pore component FYVE PF01363.21 CCU97886.1 - 8.7e-20 70.6 7.7 8.7e-20 70.6 7.7 3.1 2 1 0 3 3 3 1 FYVE zinc finger FYVE_2 PF02318.16 CCU97886.1 - 0.017 15.3 6.8 0.017 15.3 6.8 2.9 2 2 0 2 2 2 0 FYVE-type zinc finger HypA PF01155.19 CCU97886.1 - 3 7.9 14.0 3.3 7.7 3.2 3.5 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_L29e PF01779.17 CCU97887.1 - 8.6e-13 48.4 3.2 2.3e-12 47.0 3.2 1.7 1 1 0 1 1 1 1 Ribosomal L29e protein family MMM1 PF10296.9 CCU97888.1 - 1.3e-05 24.5 0.0 0.004 16.3 0.1 2.5 2 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 THDPS_M PF14789.6 CCU97888.1 - 0.072 13.2 0.8 56 3.9 0.0 3.6 3 0 0 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase middle DUF4342 PF14242.6 CCU97888.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) SSF PF00474.17 CCU97890.1 - 3.2e-14 52.6 20.4 5.4e-14 51.9 20.4 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family 2OG-FeII_Oxy PF03171.20 CCU97891.1 - 1.3e-13 51.3 0.0 2.9e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CCU97891.1 - 7.2e-13 49.3 0.0 1.6e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal FMO-like PF00743.19 CCU97892.1 - 5.9e-31 107.5 0.0 1.6e-12 46.7 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CCU97892.1 - 4.6e-13 49.1 0.1 7.2e-12 45.2 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CCU97892.1 - 4.4e-07 29.4 0.0 4.6e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CCU97892.1 - 1.7e-06 27.5 0.3 0.078 12.1 0.0 3.1 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CCU97892.1 - 2.2e-06 27.8 0.0 0.00043 20.3 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CCU97892.1 - 9.7e-05 22.5 0.0 0.0017 18.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CCU97892.1 - 0.014 15.9 0.2 7.4 7.2 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CCU97892.1 - 0.042 13.4 0.2 1.3 8.5 0.1 2.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 CCU97892.1 - 0.13 11.5 0.1 4 6.6 0.0 2.2 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 CCU97892.1 - 0.18 10.4 0.2 0.33 9.6 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein TauD PF02668.16 CCU97893.1 - 5.2e-40 137.9 0.1 6.4e-40 137.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4313 PF14190.6 CCU97893.1 - 0.16 12.0 0.0 0.52 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4313) tRNA_synthFbeta PF17759.1 CCU97894.1 - 9e-49 165.8 0.0 1.3e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CCU97894.1 - 6.5e-32 109.6 0.3 1.4e-30 105.4 0.1 2.6 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CCU97894.1 - 5.4e-26 91.3 0.0 1.1e-25 90.3 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CCU97894.1 - 7.1e-18 64.7 0.0 3.6e-16 59.2 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase B5 domain ETF_QO PF05187.13 CCU97895.1 - 1.8e-43 146.9 0.1 3.4e-43 146.0 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CCU97895.1 - 1.7e-08 34.4 0.1 0.00018 21.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CCU97895.1 - 5.3e-07 29.1 1.8 0.0002 20.6 1.7 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CCU97895.1 - 4.8e-06 26.7 0.1 1.7e-05 24.9 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CCU97895.1 - 1.5e-05 24.4 0.0 0.00022 20.6 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 CCU97895.1 - 1.6e-05 24.3 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CCU97895.1 - 7.6e-05 21.6 1.2 0.00012 21.0 1.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 CCU97895.1 - 0.00023 20.6 0.2 0.00036 20.0 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CCU97895.1 - 0.00061 18.9 0.6 0.0013 17.9 0.3 1.6 1 1 1 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CCU97895.1 - 0.00076 18.8 1.1 0.0013 18.1 1.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CCU97895.1 - 0.0014 17.9 0.3 0.0026 17.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.7 CCU97895.1 - 0.0046 17.5 1.0 0.01 16.4 1.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain NAD_binding_9 PF13454.6 CCU97895.1 - 0.016 15.2 0.2 0.029 14.4 0.2 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 CCU97895.1 - 0.044 13.1 0.1 0.07 12.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_21 PF14697.6 CCU97895.1 - 0.059 13.5 0.6 0.12 12.5 0.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Trp_halogenase PF04820.14 CCU97895.1 - 0.12 11.2 0.4 0.23 10.3 0.4 1.5 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 CCU97895.1 - 0.13 11.3 0.9 0.21 10.6 0.9 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 CCU97895.1 - 0.15 12.7 0.5 11 6.7 0.4 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_2 PF12797.7 CCU97895.1 - 0.9 9.8 3.6 0.27 11.4 0.4 1.7 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4_6 PF12837.7 CCU97895.1 - 1.9 8.7 4.2 0.83 9.8 0.7 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain DPBB_1 PF03330.18 CCU97896.1 - 3e-05 24.2 0.1 0.00013 22.2 0.1 1.9 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CCU97896.1 - 7.5e-05 22.6 0.4 0.00011 22.1 0.4 1.3 1 1 0 1 1 1 1 Barwin family FYVE PF01363.21 CCU97897.1 - 3e-17 62.5 5.1 6.3e-17 61.5 5.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 CCU97897.1 - 4.8e-12 45.4 5.2 1.1e-11 44.3 5.2 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain C1_1 PF00130.22 CCU97897.1 - 0.091 12.7 6.9 8.7 6.3 2.9 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4349 PF14257.6 CCU97897.1 - 0.33 10.4 5.5 0.73 9.2 5.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Meth_synt_2 PF01717.18 CCU97899.1 - 1e-147 491.6 0.0 1.9e-144 480.9 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CCU97899.1 - 4.4e-119 397.6 0.0 1.4e-111 372.9 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 CCU97899.1 - 0.0012 18.5 2.1 0.0012 18.5 2.1 2.1 2 0 0 2 2 2 1 Short C-terminal domain HMGL-like PF00682.19 CCU97899.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 HMGL-like Y_phosphatase PF00102.27 CCU97902.1 - 1.6e-25 90.1 0.0 2.5e-23 82.9 0.0 2.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CCU97902.1 - 2.1e-08 34.0 0.0 3.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain SLT_L PF14718.6 CCU97903.1 - 0.044 13.9 1.0 0.11 12.7 1.0 1.6 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain IF4E PF01652.18 CCU97904.1 - 8.3e-47 158.9 0.1 1.1e-46 158.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.25 CCU97905.1 - 2.9e-56 190.8 0.0 4e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97905.1 - 6.9e-28 97.6 0.0 1e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU97905.1 - 7e-05 22.3 0.0 0.00016 21.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCU97905.1 - 0.0039 17.1 0.1 0.8 9.6 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CCU97905.1 - 0.036 13.4 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CCU97905.1 - 0.049 13.3 0.1 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ALAD PF00490.21 CCU97906.1 - 4.8e-113 377.5 0.0 5.3e-113 377.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase ATP_bind_1 PF03029.17 CCU97907.1 - 1.8e-18 67.2 0.2 2.1e-18 67.0 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Hid1 PF12722.7 CCU97907.1 - 0.034 12.3 0.0 0.043 12.0 0.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cwf_Cwc_15 PF04889.12 CCU97908.1 - 3.2e-50 171.2 25.4 2.9e-49 168.1 25.4 1.9 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 CCU97908.1 - 0.00023 21.4 13.4 0.00026 21.2 13.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein MFAP1 PF06991.11 CCU97908.1 - 0.0094 15.8 13.6 0.012 15.4 13.6 1.2 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing Pet100 PF09803.9 CCU97908.1 - 0.89 10.1 5.1 9.2 6.9 1.9 2.5 2 0 0 2 2 2 0 Pet100 DUF4407 PF14362.6 CCU97908.1 - 1.3 8.4 5.6 1.7 7.9 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAPS PF04499.15 CCU97908.1 - 3.5 6.3 9.4 4.3 6.0 9.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein tRNA_m1G_MT PF01746.21 CCU97909.1 - 5.1e-22 78.5 0.0 2.5e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Pkinase PF00069.25 CCU97910.1 - 7.3e-62 209.1 0.1 1.4e-41 142.6 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97910.1 - 1.1e-25 90.4 0.1 3.5e-19 69.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CCU97910.1 - 2.7e-07 29.9 0.1 4e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CCU97910.1 - 0.00021 21.3 0.2 0.05 13.5 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CCU97910.1 - 0.0033 16.8 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCU97910.1 - 0.0054 16.1 2.7 0.021 14.2 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 CCU97910.1 - 0.016 14.0 0.0 0.029 13.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 CCU97910.1 - 0.039 13.0 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 CCU97910.1 - 0.054 12.4 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_C PF00433.24 CCU97910.1 - 0.069 13.9 0.3 0.15 12.7 0.3 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain NUFIP1 PF10453.9 CCU97910.1 - 0.13 12.1 0.5 0.31 10.9 0.1 1.9 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) GDC-P PF02347.16 CCU97911.1 - 2.3e-181 603.4 0.8 3.3e-171 569.9 0.0 2.3 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 CCU97911.1 - 2.8e-05 23.3 0.6 0.0084 15.1 0.3 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 CCU97911.1 - 0.001 18.4 0.2 0.0022 17.3 0.2 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Hexokinase_2 PF03727.16 CCU97912.1 - 2.8e-79 265.9 0.0 1.6e-78 263.5 0.0 1.9 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 CCU97912.1 - 5.6e-64 215.7 0.0 7.7e-64 215.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF1731 PF08338.11 CCU97912.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Amino_oxidase PF01593.24 CCU97913.1 - 6.9e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 CCU97913.1 - 0.084 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L44 PF00935.19 CCU97914.1 - 2.4e-36 124.0 13.0 3.8e-36 123.4 13.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Pkinase PF00069.25 CCU97915.1 - 9.6e-70 235.0 0.0 1.1e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97915.1 - 5.6e-28 97.9 0.0 7.9e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCU97915.1 - 0.017 14.1 0.2 0.31 10.0 0.1 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 CCU97915.1 - 0.74 9.1 2.5 1.3 8.3 2.5 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Slu7 PF11708.8 CCU97916.1 - 6e-93 311.5 23.2 7.8e-93 311.1 23.2 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor RRF PF01765.19 CCU97917.1 - 2.7e-25 89.2 4.1 7.1e-25 87.8 4.1 1.6 1 1 0 1 1 1 1 Ribosome recycling factor Phage_holin_7_1 PF16081.5 CCU97917.1 - 1.4 9.1 4.5 2.6 8.2 1.2 2.3 2 1 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family YtxH PF12732.7 CCU97917.1 - 2 9.0 5.9 6.7 7.3 5.9 1.8 1 1 0 1 1 1 0 YtxH-like protein TFIID-31kDa PF02291.15 CCU97918.1 - 5.1e-48 162.2 0.0 6.5e-48 161.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CCU97918.1 - 2.7e-05 24.1 0.0 5.5e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 CCU97918.1 - 0.026 14.7 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Adap_comp_sub PF00928.21 CCU97919.1 - 9.4e-22 77.6 0.0 1.4e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CCU97919.1 - 9.7e-05 22.3 0.5 0.00015 21.7 0.5 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CCU97919.1 - 0.0045 16.5 0.0 0.0076 15.7 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Plasmodium_HRP PF05403.11 CCU97919.1 - 0.12 12.1 13.1 0.21 11.3 13.1 1.2 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) Mis12 PF05859.12 CCU97921.1 - 2.2e-25 89.3 0.0 6.4e-25 87.8 0.1 1.7 2 0 0 2 2 2 1 Mis12 protein SPESP1 PF15754.5 CCU97921.1 - 0.19 10.9 0.3 0.28 10.3 0.3 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 zf-CCHC PF00098.23 CCU97922.1 - 4.9e-12 45.3 12.1 1.6e-06 27.9 1.6 2.5 2 0 0 2 2 2 2 Zinc knuckle DUF1897 PF09005.10 CCU97922.1 - 7e-07 28.6 14.7 0.0019 17.6 0.6 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1897) zf-CCHC_3 PF13917.6 CCU97922.1 - 2.7e-05 24.1 12.4 0.00053 19.9 3.8 2.4 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 CCU97922.1 - 0.00025 20.7 2.1 0.00025 20.7 2.1 2.5 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 CCU97922.1 - 0.0094 15.8 13.1 0.028 14.2 3.8 2.5 2 0 0 2 2 2 2 Zinc knuckle DZR PF12773.7 CCU97922.1 - 0.18 11.8 3.7 0.42 10.7 3.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon Tnp_zf-ribbon_2 PF13842.6 CCU97922.1 - 0.36 11.7 5.3 1.2 10.0 5.3 1.8 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-CCHC_4 PF14392.6 CCU97922.1 - 2.3 8.0 11.0 2.5 7.9 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_L37e PF01907.19 CCU97922.1 - 8.8 6.6 10.6 0.36 11.0 1.9 2.7 3 0 0 3 3 3 0 Ribosomal protein L37e HAT PF02184.16 CCU97924.1 - 1.4e-09 37.8 27.8 0.013 15.5 0.0 8.9 9 1 0 9 9 9 5 HAT (Half-A-TPR) repeat Suf PF05843.14 CCU97924.1 - 2.3e-06 27.8 8.5 0.07 13.1 0.1 5.2 2 1 2 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CCU97924.1 - 6.7e-06 26.5 0.3 0.088 13.3 0.0 4.1 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCU97924.1 - 2.1e-05 25.0 13.3 0.65 11.0 1.1 7.4 4 1 4 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCU97924.1 - 0.0022 18.3 3.4 0.027 14.8 0.0 4.3 7 0 0 7 7 7 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CCU97924.1 - 0.0028 17.6 7.6 0.095 12.7 0.5 4.1 4 1 0 4 4 4 1 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 CCU97924.1 - 0.019 15.0 1.7 19 5.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MRP-L20 PF12824.7 CCU97925.1 - 1.9e-27 96.4 2.5 4.4e-27 95.3 2.5 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Pyr_redox_2 PF07992.14 CCU97925.1 - 3.4e-13 49.5 0.0 9.3e-11 41.5 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCU97925.1 - 7.6e-05 22.1 0.1 0.088 12.1 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CCU97925.1 - 0.00012 22.1 0.0 0.065 13.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 CCU97925.1 - 0.0016 17.6 0.4 1.5 7.8 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.24 CCU97925.1 - 0.0022 17.6 0.1 0.006 16.2 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CCU97925.1 - 0.045 12.8 0.1 0.12 11.4 0.1 1.6 1 1 1 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.6 CCU97925.1 - 0.095 11.8 0.2 0.38 9.9 0.1 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 CCU97925.1 - 0.1 11.8 0.0 1.2 8.3 0.0 2.3 2 1 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 CCU97925.1 - 0.21 10.8 0.0 0.39 9.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DEAD PF00270.29 CCU97926.1 - 1.1e-22 80.7 0.0 1.7e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU97926.1 - 4e-19 69.0 0.1 1.2e-18 67.4 0.1 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AA_permease_2 PF13520.6 CCU97927.1 - 1.3e-58 198.9 47.9 1.5e-58 198.6 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease PH_4 PF15404.6 CCU97929.1 - 1.5e-20 73.7 0.9 2.9e-17 63.1 0.2 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CCU97929.1 - 9.4e-05 22.9 0.6 3.6 8.2 0.0 4.4 4 0 0 4 4 4 3 PH domain Ribosom_S12_S23 PF00164.25 CCU97930.1 - 3.9e-35 119.9 0.1 5.4e-35 119.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 EF1_GNE PF00736.19 CCU97931.1 - 3.3e-34 116.9 2.8 8.7e-34 115.6 3.0 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CCU97931.1 - 1.7e-13 50.8 8.0 1.7e-13 50.8 8.0 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 CCU97931.1 - 0.0014 18.8 0.2 0.0053 16.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF5356 PF17309.2 CCU97931.1 - 0.0075 16.2 0.2 0.013 15.5 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5356) GST_C_2 PF13410.6 CCU97931.1 - 0.022 14.8 0.0 0.11 12.5 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CCU97931.1 - 0.32 11.2 1.3 1.7 8.9 0.0 2.7 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DNA_pol3_a_NII PF11490.8 CCU97931.1 - 1.8 8.5 6.2 1.7 8.6 0.1 2.5 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus II ING PF12998.7 CCU97932.1 - 7.7e-06 26.4 0.0 1.5e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CCU97932.1 - 1.8e-05 24.5 6.8 2.8e-05 23.9 6.8 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CCU97932.1 - 0.06 13.6 1.1 0.11 12.8 1.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 CCU97932.1 - 0.14 11.7 2.6 0.25 11.0 2.6 1.3 1 0 0 1 1 1 0 PHD-finger FKBP_C PF00254.28 CCU97933.1 - 6.2e-33 113.0 0.0 7.1e-33 112.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NTF2 PF02136.20 CCU97934.1 - 1.1e-34 119.6 0.2 1.2e-34 119.4 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 CCU97934.1 - 0.0023 18.3 0.0 0.0027 18.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 CCU97934.1 - 0.15 12.2 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Asp PF00026.23 CCU97935.1 - 8.3e-67 225.8 8.2 1.3e-66 225.2 8.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCU97935.1 - 5.1e-14 52.9 6.0 2.2e-06 28.0 2.3 2.8 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CCU97935.1 - 1e-05 26.1 0.9 0.12 13.0 0.1 3.5 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CCU97935.1 - 0.00023 21.7 1.4 0.081 13.5 0.0 3.7 3 2 1 4 4 4 1 gag-polyprotein putative aspartyl protease Bromodomain PF00439.25 CCU97937.1 - 3.1e-55 184.2 0.1 1.9e-20 72.7 0.0 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.20 CCU97937.1 - 0.00013 21.7 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 CCU97937.1 - 0.015 15.7 8.7 7.4 7.0 0.0 4.4 4 0 0 4 4 4 0 HEAT repeats Med7 PF05983.11 CCU97938.1 - 3.5e-46 157.7 0.0 4.1e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 MED7 protein AAA_12 PF13087.6 CCU97939.1 - 1.1e-44 152.5 0.0 1.6e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.11 CCU97939.1 - 2.4e-36 125.5 0.0 4e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 CCU97939.1 - 3.5e-30 105.7 1.9 1.2e-15 58.0 0.2 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 CCU97939.1 - 1.4e-14 54.3 2.5 1.6e-14 54.1 0.4 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CCU97939.1 - 3.3e-11 43.7 0.1 9.1e-11 42.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CCU97939.1 - 2.5e-07 30.7 0.9 0.07 12.9 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CCU97939.1 - 2.6e-05 24.2 0.1 8.8e-05 22.4 0.0 2.0 2 1 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 CCU97939.1 - 0.0015 18.3 0.1 0.0039 17.0 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Cas_Cas4 PF01930.17 CCU97939.1 - 0.0059 16.7 0.1 0.11 12.5 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function DUF83 DUF87 PF01935.17 CCU97939.1 - 0.014 15.5 0.1 0.023 14.8 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain SRP54 PF00448.22 CCU97939.1 - 0.029 14.0 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain HSDR_N_2 PF13588.6 CCU97939.1 - 0.04 13.9 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) AAA_16 PF13191.6 CCU97939.1 - 0.067 13.6 0.1 0.067 13.6 0.1 2.6 2 1 1 3 3 3 0 AAA ATPase domain Csa1 PF06023.12 CCU97939.1 - 0.081 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 MeaB PF03308.16 CCU97939.1 - 0.1 11.6 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 CCU97939.1 - 0.27 11.5 0.8 2.7 8.3 0.0 3.0 3 1 0 3 3 3 0 AAA domain AA_permease PF00324.21 CCU97940.1 - 0 1308.8 120.4 2.4e-136 455.2 35.6 3.0 3 0 0 3 3 3 3 Amino acid permease AA_permease_2 PF13520.6 CCU97940.1 - 1.2e-126 423.1 127.4 4.1e-46 157.7 40.4 3.1 3 0 0 3 3 3 3 Amino acid permease NCE101 PF11654.8 CCU97940.1 - 4.5 7.1 10.6 5.9 6.7 0.1 4.8 6 0 0 6 6 6 0 Non-classical export protein 1 VHP PF02209.19 CCU97940.1 - 5.6 7.1 5.9 0.47 10.6 0.1 2.2 3 0 0 3 3 3 0 Villin headpiece domain AA_permease PF00324.21 CCU97941.1 - 2.4e-74 250.7 14.2 2.4e-74 250.7 14.2 1.7 1 1 1 2 2 2 1 Amino acid permease AA_permease_2 PF13520.6 CCU97941.1 - 3.4e-23 82.2 11.5 4.5e-23 81.8 11.5 1.1 1 0 0 1 1 1 1 Amino acid permease SKIP_SNW PF02731.15 CCU97942.1 - 6.5e-63 211.2 3.4 6.5e-63 211.2 3.4 2.4 3 0 0 3 3 3 1 SKIP/SNW domain MRC1 PF09444.10 CCU97942.1 - 1.4 9.4 21.4 8.2 6.9 21.4 2.1 1 1 0 1 1 1 0 MRC1-like domain Coprogen_oxidas PF01218.18 CCU97943.1 - 1e-114 382.3 0.0 1.4e-114 381.9 0.0 1.2 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF3794 PF12673.7 CCU97943.1 - 0.19 12.1 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3794) DUF4112 PF13430.6 CCU97944.1 - 6.3e-32 110.0 0.1 8.5e-32 109.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Pkinase PF00069.25 CCU97945.1 - 1.1e-52 179.1 0.0 1.8e-51 175.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU97945.1 - 4.1e-25 88.5 0.0 1.4e-24 86.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU97945.1 - 5.1e-07 29.3 0.0 8.4e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_3 PF14593.6 CCU97945.1 - 5.4e-07 29.7 0.0 0.0049 16.9 0.0 2.4 2 0 0 2 2 2 2 PH domain Kdo PF06293.14 CCU97945.1 - 0.0067 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CCU97945.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CCU97945.1 - 0.028 14.4 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF5476 PF17570.2 CCU97946.1 - 2.8 8.4 22.2 32 5.0 0.0 7.5 6 1 1 7 7 7 0 Family of unknown function (DUF5476) HC2 PF07382.11 CCU97946.1 - 8.8 6.4 16.4 0.49 10.5 1.5 2.9 1 1 1 3 3 3 0 Histone H1-like nucleoprotein HC2 RRM_1 PF00076.22 CCU97947.1 - 3.8e-12 45.9 0.0 1.5e-05 24.7 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCU97947.1 - 2.9e-05 24.1 0.0 5.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif polyprenyl_synt PF00348.17 CCU97948.1 - 1.3e-65 221.1 0.0 4.5e-65 219.3 0.0 1.9 1 1 0 1 1 1 1 Polyprenyl synthetase Pept_tRNA_hydro PF01195.19 CCU97949.1 - 8.4e-26 90.9 0.0 1.9e-25 89.8 0.0 1.5 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase zf-HC2 PF13490.6 CCU97949.1 - 0.05 13.9 0.1 2.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Putative zinc-finger HEAT_2 PF13646.6 CCU97949.1 - 0.065 13.6 0.1 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 HEAT repeats F-box-like PF12937.7 CCU97951.1 - 0.03 14.2 1.7 0.068 13.1 0.4 2.5 2 0 0 2 2 2 0 F-box-like DUF572 PF04502.13 CCU97952.1 - 3.4e-75 253.7 4.0 3.8e-75 253.6 4.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 CCU97952.1 - 0.0045 16.9 0.6 1.2 9.1 0.1 2.5 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_12 PF11331.8 CCU97952.1 - 0.19 11.6 0.5 11 5.9 0.1 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain GCIP PF13324.6 CCU97953.1 - 1.3e-12 47.9 2.4 6.8e-11 42.3 0.9 3.0 2 1 0 2 2 2 2 Grap2 and cyclin-D-interacting FlgN PF05130.12 CCU97953.1 - 6.1 7.4 8.8 20 5.7 0.5 3.4 3 2 2 5 5 5 0 FlgN protein Tyr_Deacylase PF02580.16 CCU97954.1 - 1.7e-43 148.6 0.0 2e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Ku_PK_bind PF08785.11 CCU97954.1 - 0.19 11.9 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Ku C terminal domain like Inositol_P PF00459.25 CCU97956.1 - 4.5e-66 223.2 0.0 5.1e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family adh_short PF00106.25 CCU97959.1 - 8.8e-22 77.5 0.0 2.5e-21 76.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCU97959.1 - 3.4e-12 46.4 0.0 4.3e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCU97959.1 - 1.9e-08 34.4 0.0 2.5e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CCU97959.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SMC_hinge PF06470.13 CCU97959.1 - 0.037 14.3 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain GDP_Man_Dehyd PF16363.5 CCU97959.1 - 0.079 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PrpR_N PF06506.11 CCU97959.1 - 0.2 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Propionate catabolism activator zf-C2H2_2 PF12756.7 CCU97960.1 - 0.013 15.8 0.1 0.029 14.7 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) YL1 PF05764.13 CCU97960.1 - 0.015 15.4 27.4 0.019 15.1 27.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Asp-B-Hydro_N PF05279.11 CCU97960.1 - 0.22 11.5 22.1 0.33 11.0 22.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-C2H2_3rep PF18868.1 CCU97960.1 - 0.96 10.1 3.3 0.48 11.1 0.2 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF4407 PF14362.6 CCU97960.1 - 2.9 7.2 15.9 3.6 6.9 15.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 CCU97960.1 - 3.5 6.6 17.6 5 6.1 17.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GREB1 PF15782.5 CCU97960.1 - 3.9 4.5 9.2 4.6 4.2 9.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 CCU97960.1 - 4.2 6.3 9.9 6.3 5.7 9.9 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Hamartin PF04388.12 CCU97960.1 - 6.4 5.3 12.8 8.1 5.0 12.8 1.1 1 0 0 1 1 1 0 Hamartin protein Metallophos PF00149.28 CCU97961.1 - 5.7e-05 23.7 0.0 8.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GCD14 PF08704.10 CCU97963.1 - 1.6e-78 263.8 3.7 5.4e-45 154.0 0.6 3.1 2 1 0 3 3 3 3 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CCU97963.1 - 0.0018 18.1 0.0 1.7 8.4 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain PCMT PF01135.19 CCU97963.1 - 0.018 14.8 0.0 0.073 12.8 0.0 1.9 3 0 0 3 3 3 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 CCU97963.1 - 0.022 15.8 0.1 0.093 13.8 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain GCD14_N PF14801.6 CCU97963.1 - 0.055 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term RrnaAD PF00398.20 CCU97963.1 - 0.084 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CBF PF03914.17 CCU97964.1 - 8e-48 162.7 3.4 3.1e-47 160.8 0.0 3.2 3 1 0 3 3 3 1 CBF/Mak21 family Adaptin_N PF01602.20 CCU97964.1 - 0.0016 17.1 0.0 0.99 7.9 0.0 2.3 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 CCU97964.1 - 0.0024 17.9 0.4 0.018 15.1 0.1 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 TFIIS_M PF07500.14 CCU97965.1 - 3.9e-30 104.6 1.3 3.9e-30 104.6 1.3 2.7 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CCU97965.1 - 8.2e-19 67.2 6.9 1.6e-18 66.2 6.9 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CCU97965.1 - 1.7e-08 34.3 0.7 6.1e-08 32.6 0.7 2.0 1 1 0 1 1 1 1 TFIIS helical bundle-like domain 2-Hacid_dh PF00389.30 CCU97965.1 - 0.026 14.2 0.1 0.041 13.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF1484 PF07363.11 CCU97965.1 - 0.056 14.5 0.1 0.056 14.5 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1484) Baculo_LEF5_C PF11792.8 CCU97965.1 - 0.11 12.2 0.1 0.35 10.6 0.1 1.9 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Cytochrome_C554 PF13435.6 CCU97965.1 - 2.4 9.2 9.9 0.63 11.0 4.3 2.4 2 0 0 2 2 2 0 Cytochrome c554 and c-prime DnaJ PF00226.31 CCU97966.1 - 2.1e-24 85.4 0.3 3.2e-24 84.8 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain IBR PF01485.21 CCU97966.1 - 0.11 12.8 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DnaJ-X PF14308.6 CCU97967.1 - 5.8e-42 143.5 2.8 5.8e-42 143.5 2.8 2.3 2 1 0 2 2 2 1 X-domain of DnaJ-containing TMEM187 PF15100.6 CCU97967.1 - 0.025 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 TMEM187 protein family GvpL_GvpF PF06386.11 CCU97967.1 - 5.4 6.9 14.2 0.45 10.4 6.9 2.1 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF ThiF PF00899.21 CCU97968.1 - 2.8e-19 69.4 0.0 9.6e-19 67.7 0.0 1.8 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 CCU97968.1 - 8e-08 32.4 1.4 0.064 13.5 0.1 3.9 3 0 0 3 3 3 3 Ubiquitin-activating enzyme E1 four-helix bundle DUF982 PF06169.12 CCU97968.1 - 6.8 6.8 7.7 0.42 10.7 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF982) PRIMA1 PF16101.5 CCU97969.1 - 0.017 15.2 0.2 0.032 14.2 0.2 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 UCH PF00443.29 CCU97970.1 - 3.7e-33 115.1 0.0 4.5e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCU97970.1 - 7.4e-11 42.2 0.0 8.4e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C2H2 PF00096.26 CCU97970.1 - 0.35 11.4 4.3 1.4 9.6 0.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Abhydrolase_3 PF07859.13 CCU97971.1 - 1.6e-21 77.1 0.0 4.4e-21 75.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CCU97971.1 - 4.4e-17 62.0 0.0 1.4e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase zf-C2H2_aberr PF17017.5 CCU97972.1 - 1.3e-05 25.4 2.4 0.063 13.4 0.2 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 CCU97972.1 - 0.0017 18.7 11.4 0.12 12.9 0.6 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCU97972.1 - 5.3 8.2 14.3 8.4 7.5 0.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Glyoxalase PF00903.25 CCU97973.1 - 1.6e-18 67.1 0.1 2e-18 66.8 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CCU97973.1 - 1.9e-06 28.1 0.0 3e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 CCU97973.1 - 0.0007 20.4 0.0 0.00099 19.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 CCU97973.1 - 0.0056 16.8 0.0 0.0068 16.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain NIL PF09383.10 CCU97973.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 NIL domain tRNA-synt_1b PF00579.25 CCU97974.1 - 2e-63 214.5 0.0 5e-63 213.2 0.0 1.6 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) EMP24_GP25L PF01105.24 CCU97975.1 - 6.5e-28 97.9 0.1 8e-28 97.6 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UL45 PF05473.12 CCU97976.1 - 0.12 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like CitMHS_2 PF16980.5 CCU97976.1 - 0.23 10.1 0.9 0.26 9.9 0.9 1.0 1 0 0 1 1 1 0 Putative citrate transport Sox17_18_mid PF12067.8 CCU97977.1 - 0.14 12.3 4.4 6.9 6.8 0.9 2.9 2 0 0 2 2 2 0 Sox 17/18 central domain WD40 PF00400.32 CCU97978.1 - 7.5e-19 67.7 16.4 0.0019 19.0 0.2 6.7 5 1 1 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU97978.1 - 6.1e-09 36.1 1.3 0.01 16.1 0.0 4.2 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCU97978.1 - 4.4e-05 22.6 0.0 1.4 7.8 0.0 4.1 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein HA2 PF04408.23 CCU97979.1 - 8e-27 93.7 0.0 1.5e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CCU97979.1 - 4.5e-20 71.8 0.0 1.6e-19 70.0 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CCU97979.1 - 5.1e-12 46.1 0.0 2.8e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCU97979.1 - 4.3e-08 33.1 0.1 8.8e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCU97979.1 - 5.2e-05 23.5 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCU97979.1 - 0.00062 20.1 0.2 0.0013 19.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 CCU97979.1 - 0.01 15.8 0.3 0.03 14.3 0.2 1.7 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_30 PF13604.6 CCU97979.1 - 0.029 14.1 0.1 0.057 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CCU97979.1 - 0.05 12.7 0.0 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 CCU97979.1 - 0.07 12.7 0.8 0.63 9.6 0.8 2.2 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 CCU97979.1 - 0.11 13.1 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Thioredoxin_8 PF13905.6 CCU97979.1 - 0.11 12.8 0.0 14 6.1 0.0 3.2 3 0 0 3 3 3 0 Thioredoxin-like DUF2075 PF09848.9 CCU97979.1 - 0.16 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CCU97979.1 - 0.17 11.3 0.0 0.46 9.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 CCU97979.1 - 0.17 11.9 0.0 26 4.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Nucleopor_Nup85 PF07575.13 CCU97980.1 - 1.5e-75 254.9 0.0 2.9e-75 253.9 0.0 1.4 1 1 0 1 1 1 1 Nup85 Nucleoporin Ribosomal_L14 PF00238.19 CCU97981.1 - 9.9e-36 122.5 0.0 1.2e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e GTP_cyclohydroI PF01227.22 CCU97982.1 - 1.5e-73 246.0 0.1 1.8e-73 245.8 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CCU97982.1 - 0.00089 19.4 0.0 0.0025 17.9 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 CCU97982.1 - 0.048 13.6 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain KAR PF15222.6 CCU97982.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Kidney androgen-regulated Cyt-b5 PF00173.28 CCU97983.1 - 8.4e-24 83.5 0.2 9.3e-24 83.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.6 CCU97983.1 - 0.097 12.8 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Cpn60_TCP1 PF00118.24 CCU97984.1 - 7.1e-162 539.4 1.6 8.3e-162 539.2 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chitin_synth_1 PF01644.17 CCU97985.1 - 1.2e-71 240.0 0.1 2e-71 239.2 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CCU97985.1 - 1.7e-26 92.0 0.1 1.3e-25 89.1 0.0 2.7 3 0 0 3 3 3 1 Chitin synthase N-terminal EF-hand_4 PF12763.7 CCU97985.1 - 4.2e-16 58.8 0.0 1.1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Chitin_synth_2 PF03142.15 CCU97985.1 - 5e-10 38.6 0.0 1.3e-09 37.3 0.0 1.5 1 1 1 2 2 2 1 Chitin synthase WH2 PF02205.20 CCU97985.1 - 1.4e-09 37.5 1.4 2.7e-09 36.6 1.4 1.5 1 0 0 1 1 1 1 WH2 motif SH3_1 PF00018.28 CCU97985.1 - 1.8e-09 37.1 0.0 6.9e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CCU97985.1 - 3.4e-09 36.4 0.1 1.9e-06 27.6 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CCU97985.1 - 0.00013 21.5 0.0 0.0009 18.9 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain EF-hand_7 PF13499.6 CCU97985.1 - 0.079 13.4 0.0 0.65 10.5 0.0 2.4 2 1 1 3 3 3 0 EF-hand domain pair Rx_N PF18052.1 CCU97985.1 - 0.52 10.6 3.3 1.3 9.4 3.3 1.6 1 0 0 1 1 1 0 Rx N-terminal domain PTPlike_phytase PF14566.6 CCU97986.1 - 8e-135 445.1 2.2 1.2e-48 165.2 0.4 3.3 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase PF00102.27 CCU97986.1 - 4.2e-06 26.5 0.1 0.039 13.5 0.0 3.3 3 0 0 3 3 3 2 Protein-tyrosine phosphatase DSPc PF00782.20 CCU97986.1 - 9e-06 25.5 0.0 0.52 10.1 0.0 3.7 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CCU97986.1 - 5.6e-05 23.2 1.6 0.69 9.8 0.0 3.8 4 0 0 4 4 4 2 Tyrosine phosphatase family Ribosomal_L22 PF00237.19 CCU97987.1 - 1.3e-37 128.1 0.0 2e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e E1_dh PF00676.20 CCU97988.1 - 7e-63 212.3 0.0 1e-62 211.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CCU97988.1 - 7.4e-61 204.9 0.0 1.1e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CCU97988.1 - 3.9e-46 156.5 0.0 7.4e-46 155.6 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CCU97988.1 - 3.5e-17 61.7 2.3 7.4e-17 60.7 2.3 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus ELFV_dehydrog PF00208.21 CCU97989.1 - 1.1e-14 54.8 0.0 3.6e-12 46.5 0.0 2.1 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Spore_III_AB PF09548.10 CCU97989.1 - 0.2 11.8 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RRM_1 PF00076.22 CCU97990.1 - 2.1e-60 200.4 0.0 6e-19 67.6 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCU97990.1 - 2.4e-05 24.3 0.0 2.1 8.5 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 CCU97990.1 - 0.0004 20.4 0.4 7.6 6.6 0.0 4.1 4 0 0 4 4 4 2 RNA binding motif RRM_Rrp7 PF17799.1 CCU97990.1 - 0.009 15.8 3.0 0.69 9.7 0.0 4.4 5 1 1 6 6 6 1 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 CCU97990.1 - 0.017 15.1 0.0 0.9 9.6 0.0 3.3 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif DUF2271 PF10029.9 CCU97990.1 - 0.36 10.5 3.5 0.25 11.0 0.7 2.2 2 0 0 2 2 2 0 Predicted periplasmic protein (DUF2271) NOA36 PF06524.12 CCU97990.1 - 0.68 9.2 11.5 1.5 8.1 11.5 1.5 1 0 0 1 1 1 0 NOA36 protein Cutinase PF01083.22 CCU97991.1 - 0.082 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Cutinase WD40 PF00400.32 CCU97992.1 - 3.3e-47 157.5 14.7 5.7e-11 42.8 0.7 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU97992.1 - 1.1e-19 70.5 0.0 0.026 14.8 0.0 6.2 5 1 1 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCU97992.1 - 2.8e-05 23.2 0.0 0.065 12.2 0.0 4.0 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 CCU97992.1 - 0.11 12.5 0.8 8.7 6.2 0.0 2.7 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Zn_clus PF00172.18 CCU97993.1 - 1.4e-05 25.1 10.0 2.6e-05 24.3 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CCU97993.1 - 0.003 16.7 0.1 0.0056 15.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3038 PF11237.8 CCU97993.1 - 0.019 15.0 0.1 0.052 13.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) SRP68 PF16969.5 CCU97994.1 - 8.5e-47 160.4 10.7 2.2e-46 159.0 10.6 1.7 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 Maf PF02545.14 CCU97995.1 - 3.2e-49 167.0 0.0 3.8e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein MRP-S25 PF13741.6 CCU97996.1 - 1.8e-14 53.9 0.0 2.4e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 2-Hacid_dh_C PF02826.19 CCU97997.1 - 7.8e-51 172.0 0.0 1.2e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCU97997.1 - 1.9e-34 118.2 0.0 2.5e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CCU97997.1 - 0.0034 17.6 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 CCU97997.1 - 0.039 13.8 0.0 6.9 6.5 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M15_4 PF13539.6 CCU97997.1 - 0.077 13.5 0.0 0.38 11.3 0.0 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase AdoHcyase_NAD PF00670.21 CCU97997.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Septin PF00735.18 CCU97998.1 - 8e-89 297.6 2.6 2.1e-87 293.0 0.1 2.4 2 1 0 2 2 2 1 Septin Chs7 PF12271.8 CCU97999.1 - 5e-81 272.2 20.2 5.9e-81 272.0 20.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Na_Ala_symp PF01235.17 CCU97999.1 - 0.036 13.4 8.8 0.075 12.3 8.8 1.5 1 1 0 1 1 1 0 Sodium:alanine symporter family COX7a PF02238.15 CCU98000.1 - 3.2e-19 69.0 0.8 4.3e-19 68.6 0.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII TrmO_C PF18389.1 CCU98000.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 TrmO C-terminal domain Oxidored_FMN PF00724.20 CCU98001.1 - 6.8e-53 180.1 0.0 9.7e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CDC73_C PF05179.14 CCU98002.1 - 6.5e-30 103.9 0.0 1e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 CCU98002.1 - 0.00085 18.7 0.0 0.0014 18.0 0.0 1.4 1 1 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal Chorismate_synt PF01264.21 CCU98003.1 - 4.1e-139 462.8 0.0 4.7e-139 462.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase PV-1 PF06637.11 CCU98004.1 - 0.081 11.7 5.7 0.12 11.2 5.7 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Phage-A118_gp45 PF10653.9 CCU98004.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein gp45 of Bacteriophage A118 Menin PF05053.13 CCU98004.1 - 5.9 5.1 12.1 8.2 4.7 12.1 1.1 1 0 0 1 1 1 0 Menin NOT2_3_5 PF04153.18 CCU98005.1 - 1.1e-35 122.5 1.3 1.5e-35 122.1 1.3 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family ADH_zinc_N PF00107.26 CCU98006.1 - 1.6e-27 96.1 0.0 2.7e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCU98006.1 - 2.1e-13 51.5 0.0 5.7e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCU98006.1 - 2.1e-08 34.0 0.0 3.3e-07 30.2 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain HupF_HypC PF01455.18 CCU98006.1 - 0.044 13.9 0.7 0.14 12.4 0.1 2.1 2 0 0 2 2 2 0 HupF/HypC family PGM_PMM_I PF02878.16 CCU98007.1 - 1.4e-36 125.3 0.1 2.1e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CCU98007.1 - 1.6e-27 95.9 0.0 3.1e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CCU98007.1 - 3.7e-17 62.8 0.0 9.3e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CCU98007.1 - 3.7e-06 27.0 0.0 9.2e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain tRNA_int_endo PF01974.17 CCU98008.1 - 1.4e-16 60.3 0.0 2.5e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Presenilin PF01080.17 CCU98008.1 - 0.014 14.2 0.1 0.018 13.8 0.1 1.1 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 CCU98008.1 - 1.1 8.0 3.6 1.5 7.5 3.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PI3Ka PF00613.20 CCU98009.1 - 1.2e-46 158.5 0.8 1.9e-46 157.8 0.8 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CCU98009.1 - 1.8e-45 155.7 0.0 1.7e-31 110.0 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 CCU98009.1 - 0.00048 20.1 0.0 0.00086 19.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 CCU98009.1 - 0.0038 16.6 0.0 0.0075 15.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) ALG11_N PF15924.5 CCU98010.1 - 8.6e-80 267.7 0.0 1.2e-79 267.2 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CCU98010.1 - 2.5e-17 63.0 0.0 5.1e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCU98010.1 - 1.5e-07 32.0 0.0 3.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCU98010.1 - 0.0044 17.0 0.2 0.01 15.9 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Mito_carr PF00153.27 CCU98011.1 - 3.4e-34 116.6 4.5 3.2e-16 59.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ETF PF01012.21 CCU98012.1 - 3.3e-42 144.4 2.0 4.4e-42 144.0 2.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain EFG_C PF00679.24 CCU98012.1 - 0.08 13.0 0.0 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 Elongation factor G C-terminus AAA_11 PF13086.6 CCU98013.1 - 7.1e-63 212.8 0.0 1.2e-62 212.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 CCU98013.1 - 2.2e-56 190.6 0.0 3.4e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCU98013.1 - 4.6e-12 46.1 0.5 9e-07 28.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CCU98013.1 - 4.9e-09 36.3 0.0 0.0058 16.4 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CCU98013.1 - 3.8e-08 33.8 0.0 9.3e-07 29.3 0.0 2.8 2 2 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CCU98013.1 - 7.1e-05 22.3 0.1 0.00015 21.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.6 CCU98013.1 - 0.00016 21.4 0.0 0.00041 20.1 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 CCU98013.1 - 0.00039 20.0 0.0 0.011 15.3 0.0 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 CCU98013.1 - 0.00061 19.3 0.0 1.5 8.3 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_33 PF13671.6 CCU98013.1 - 0.0012 19.0 0.1 0.0029 17.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CCU98013.1 - 0.002 18.6 0.0 0.0063 16.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCU98013.1 - 0.002 18.4 3.1 0.015 15.5 0.2 3.8 4 1 0 4 4 3 1 AAA domain AAA_25 PF13481.6 CCU98013.1 - 0.0023 17.5 0.3 0.013 15.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 CCU98013.1 - 0.0055 16.0 0.1 3 7.0 0.0 2.9 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 CCU98013.1 - 0.0083 16.0 0.0 0.24 11.2 0.0 2.5 2 0 0 2 2 2 1 Helicase ResIII PF04851.15 CCU98013.1 - 0.0099 15.9 0.0 0.067 13.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD_C PF13361.6 CCU98013.1 - 0.015 14.7 0.1 0.95 8.8 0.1 2.2 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain NACHT PF05729.12 CCU98013.1 - 0.016 15.1 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 CCU98013.1 - 0.043 14.2 0.2 0.043 14.2 0.2 2.6 3 1 0 3 3 2 0 AAA ATPase domain RNA_helicase PF00910.22 CCU98013.1 - 0.06 13.8 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CCU98013.1 - 0.061 12.8 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 CCU98013.1 - 0.066 12.9 0.0 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain EF-hand_7 PF13499.6 CCU98014.1 - 2.3e-25 88.8 3.9 4.9e-16 58.9 0.7 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CCU98014.1 - 8.5e-25 84.4 7.3 9e-08 31.1 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 CCU98014.1 - 8.6e-22 75.2 4.0 3.2e-06 26.6 0.0 5.3 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CCU98014.1 - 5.9e-14 51.6 8.0 4.9e-05 23.1 0.3 4.1 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CCU98014.1 - 2e-12 46.0 7.9 0.0012 18.2 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 CCU98014.1 - 2.4e-09 37.1 2.6 0.0087 16.0 0.0 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CCU98014.1 - 0.00035 20.8 1.1 0.14 12.5 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CCU98014.1 - 0.00081 19.7 1.6 3.1 8.2 0.2 3.5 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 CCU98014.1 - 0.11 11.3 0.1 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_3 PF09069.11 CCU98014.1 - 0.12 12.8 0.0 0.5 10.8 0.0 1.9 2 1 0 2 2 2 0 EF-hand Caleosin PF05042.13 CCU98014.1 - 0.19 11.7 1.2 36 4.2 0.0 3.1 2 1 0 3 3 3 0 Caleosin related protein Glycos_transf_3 PF00591.21 CCU98015.1 - 5e-65 219.6 0.0 5.8e-63 212.8 0.0 2.1 1 1 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 CCU98015.1 - 0.0006 19.6 0.6 0.0018 18.1 0.0 2.1 3 0 0 3 3 3 1 Glycosyl transferase family, helical bundle domain EF-hand_7 PF13499.6 CCU98016.1 - 2e-09 37.8 0.1 4.8e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CCU98016.1 - 8.9e-08 31.5 0.0 0.0042 16.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CCU98016.1 - 2.6e-06 26.6 0.0 0.014 14.9 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CCU98016.1 - 1.4e-05 24.3 0.0 0.0028 17.1 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CCU98016.1 - 0.011 15.6 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair ABC_membrane PF00664.23 CCU98017.1 - 4.1e-117 390.7 30.3 1.5e-65 221.6 12.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCU98017.1 - 1.3e-69 233.0 0.0 3e-35 121.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCU98017.1 - 1.6e-14 53.9 0.5 0.00026 20.5 0.0 4.1 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CCU98017.1 - 1.7e-07 30.4 0.2 0.013 14.4 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 CCU98017.1 - 8.8e-07 29.5 1.0 0.018 15.4 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CCU98017.1 - 8.9e-07 29.0 0.0 0.032 14.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCU98017.1 - 1.7e-06 27.7 2.5 0.0012 18.6 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CCU98017.1 - 2.5e-06 27.8 2.0 0.1 12.8 0.2 3.8 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CCU98017.1 - 3.3e-06 27.1 0.0 0.03 14.0 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CCU98017.1 - 1.2e-05 25.3 0.5 2.1 8.4 0.0 3.9 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 CCU98017.1 - 1.9e-05 24.6 0.0 0.12 12.3 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 CCU98017.1 - 2.7e-05 24.0 0.4 0.42 10.3 0.2 3.5 3 1 0 3 3 3 2 AAA domain DUF87 PF01935.17 CCU98017.1 - 5.7e-05 23.3 0.1 0.026 14.6 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA PF00004.29 CCU98017.1 - 6.7e-05 23.3 0.6 4.1 7.8 0.1 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CCU98017.1 - 8.1e-05 22.0 0.0 0.045 13.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin SbcCD_C PF13558.6 CCU98017.1 - 0.0005 20.3 3.6 1.8 8.9 0.1 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 CCU98017.1 - 0.00095 19.1 0.0 1.7 8.6 0.1 2.8 2 1 0 2 2 2 2 Rad17 P-loop domain G-alpha PF00503.20 CCU98017.1 - 0.00098 18.4 0.0 0.89 8.6 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.6 CCU98017.1 - 0.0029 17.2 2.0 1.3 8.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CCU98017.1 - 0.0044 17.6 0.0 0.64 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCU98017.1 - 0.0065 17.0 0.0 2.9 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CCU98017.1 - 0.015 15.7 0.4 40 4.6 0.0 4.1 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 CCU98017.1 - 0.017 15.3 0.0 4.7 7.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCU98017.1 - 0.023 15.1 0.0 20 5.7 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_7 PF12775.7 CCU98017.1 - 0.023 14.2 0.0 4 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 CCU98017.1 - 0.024 14.4 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CCU98017.1 - 0.047 12.9 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_10 PF12846.7 CCU98017.1 - 0.069 12.1 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.18 CCU98017.1 - 0.077 12.3 0.1 5.4 6.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.18 CCU98017.1 - 0.09 12.5 0.0 10 5.8 0.0 2.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 CCU98017.1 - 0.094 13.0 0.6 6.3 7.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 CCU98017.1 - 0.15 12.0 0.2 22 4.9 0.0 2.9 3 0 0 3 3 3 0 Adenylylsulphate kinase Coiled-coil_56 PF09813.9 CCU98017.1 - 0.17 12.0 0.0 0.51 10.4 0.0 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 Baculo_11_kDa PF06143.11 CCU98017.1 - 1.7 8.2 4.9 2.1 8.0 0.2 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family Formyl_trans_N PF00551.19 CCU98018.1 - 4.1e-34 117.9 0.1 9.5e-19 67.8 0.3 2.3 2 0 0 2 2 2 2 Formyl transferase Dynamin_N PF00350.23 CCU98019.1 - 1.1e-18 67.9 0.1 6.2e-18 65.4 0.1 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CCU98019.1 - 3.1e-12 46.6 0.1 2.6e-11 43.6 0.0 2.7 2 2 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCU98019.1 - 1e-08 35.0 0.6 1.8e-06 27.6 0.1 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCU98019.1 - 0.00037 20.4 0.3 0.37 10.7 0.1 3.2 3 0 0 3 3 3 1 RsgA GTPase cobW PF02492.19 CCU98019.1 - 0.00072 19.2 1.4 0.0072 15.9 1.4 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 CCU98019.1 - 0.0012 19.0 0.8 0.57 10.4 0.0 3.0 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CCU98019.1 - 0.0014 18.3 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain PglZ PF08665.12 CCU98019.1 - 0.0092 16.1 2.2 0.42 10.7 0.1 2.8 3 0 0 3 3 3 1 PglZ domain IIGP PF05049.13 CCU98019.1 - 0.017 14.2 0.1 0.056 12.5 0.0 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) TsaE PF02367.17 CCU98019.1 - 0.018 15.1 0.0 0.058 13.4 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 CCU98019.1 - 0.018 14.6 0.1 7 6.2 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.18 CCU98019.1 - 0.023 14.0 0.0 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.18 CCU98019.1 - 0.057 12.7 0.2 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.22 CCU98019.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 CCU98019.1 - 0.28 11.5 3.1 3 8.2 3.1 2.9 1 1 0 1 1 1 0 AAA ATPase domain Abhydrolase_1 PF00561.20 CCU98020.1 - 5.4e-11 42.6 0.0 1.3e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCU98020.1 - 3e-07 29.9 0.4 0.00035 19.9 0.1 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 DUF1057 PF06342.12 CCU98020.1 - 0.022 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_4 PF08386.10 CCU98020.1 - 0.023 14.8 0.1 0.071 13.2 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein DLH PF01738.18 CCU98020.1 - 0.056 13.0 0.0 0.5 9.9 0.0 2.3 3 0 0 3 3 3 0 Dienelactone hydrolase family Med26_M PF15694.5 CCU98020.1 - 0.14 12.1 0.2 0.24 11.4 0.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 26 middle domain DUF615 PF04751.14 CCU98020.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Ribosomal_L23eN PF03939.13 CCU98021.1 - 1e-21 76.8 8.9 1e-21 76.8 8.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CCU98021.1 - 2e-15 56.9 2.2 2e-15 56.9 2.2 2.0 2 1 0 2 2 2 1 Ribosomal protein L23 RNase_PH PF01138.21 CCU98022.1 - 1.4e-17 64.4 0.0 2.3e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCU98022.1 - 2.6e-06 27.4 0.0 5.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Aconitase PF00330.20 CCU98023.1 - 1.6e-160 535.1 0.0 1.9e-160 534.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCU98023.1 - 3.7e-40 137.3 0.0 6.8e-40 136.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ATP-synt_C PF00137.21 CCU98024.1 - 5.2e-34 116.4 35.4 6.6e-22 77.6 15.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Peptidase_M16_C PF05193.21 CCU98025.1 - 2.1e-40 138.7 0.0 2.2e-37 128.8 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCU98025.1 - 1.1e-36 126.0 1.0 8.1e-36 123.2 0.4 2.6 3 1 0 3 3 3 1 Insulinase (Peptidase family M16) ChiW_Ig_like PF18683.1 CCU98025.1 - 0.032 14.5 0.2 0.079 13.2 0.2 1.7 1 0 0 1 1 1 0 Chitinase W immunoglobulin-like domain M16C_assoc PF08367.11 CCU98025.1 - 0.1 11.7 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase M16C associated zf-RING_UBOX PF13445.6 CCU98026.1 - 1.6e-07 31.2 7.5 4.1e-07 29.9 4.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CCU98026.1 - 4.4e-07 29.6 7.9 4.8e-05 23.1 4.5 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCU98026.1 - 1.6e-06 27.9 4.9 1.6e-06 27.9 4.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCU98026.1 - 2.7e-06 27.1 6.0 1.5e-05 24.7 3.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCU98026.1 - 2e-05 24.8 10.1 9.5e-05 22.7 5.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CCU98026.1 - 7.9e-05 22.5 8.2 0.00016 21.6 4.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCU98026.1 - 0.00095 19.0 11.2 0.027 14.4 8.5 2.7 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CCU98026.1 - 0.72 9.9 3.2 30 4.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1644 PF07800.12 CCU98026.1 - 3 7.9 0.0 3 7.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) zf-C3HC4_4 PF15227.6 CCU98026.1 - 5.8 7.2 14.8 1.1 9.4 8.8 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Med6 PF04934.14 CCU98027.1 - 1.3e-12 47.7 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Peptidase_S24 PF00717.23 CCU98029.1 - 3.8e-09 36.4 0.0 7.9e-09 35.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like PAP_central PF04928.17 CCU98031.1 - 2.1e-113 377.4 0.0 2.9e-113 376.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CCU98031.1 - 1e-48 165.2 0.0 2e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CCU98031.1 - 9.3e-12 45.1 0.0 2.5e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.6 CCU98031.1 - 0.024 14.9 0.0 0.52 10.5 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase beta palm Polbeta PF18765.1 CCU98031.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 CCU98031.1 - 0.16 11.7 0.1 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain ENTH PF01417.20 CCU98032.1 - 3.2e-34 117.7 0.1 5.7e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CCU98032.1 - 0.06 12.3 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 ANTH domain VHS PF00790.19 CCU98032.1 - 0.066 13.1 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 VHS domain Proteasome PF00227.26 CCU98033.1 - 4.7e-53 179.5 0.1 5.9e-53 179.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCU98033.1 - 8.3e-14 50.9 0.0 1.9e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TRAPPC10 PF12584.8 CCU98034.1 - 2.5e-12 46.8 0.1 7.6e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 RPAP1_C PF08620.10 CCU98035.1 - 7.7e-23 80.4 0.2 7.7e-23 80.4 0.2 2.1 3 0 0 3 3 3 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 CCU98035.1 - 0.00081 19.1 0.1 0.00081 19.1 0.1 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal TFIID-18kDa PF02269.16 CCU98036.1 - 7.6e-19 67.5 0.2 7.6e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit Pyr_redox_2 PF07992.14 CCU98037.1 - 6.8e-70 235.6 1.2 6.8e-70 235.6 1.2 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CCU98037.1 - 1.1e-31 109.3 2.5 2.9e-31 108.0 1.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CCU98037.1 - 3.4e-22 78.8 4.3 4.4e-19 68.8 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCU98037.1 - 5.2e-19 68.6 0.2 2.5e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCU98037.1 - 4e-09 36.3 0.1 1e-08 35.0 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CCU98037.1 - 1.5e-08 34.1 3.1 1.6e-05 24.2 0.4 2.9 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 CCU98037.1 - 2.2e-07 30.0 3.7 0.0027 16.5 1.4 3.0 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 CCU98037.1 - 1.6e-05 24.2 0.0 5.4e-05 22.5 0.0 1.8 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 CCU98037.1 - 0.00012 21.5 3.8 0.19 10.9 1.0 2.5 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 CCU98037.1 - 0.00034 19.8 4.1 0.0013 17.9 1.0 2.7 3 1 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CCU98037.1 - 0.001 19.3 1.1 0.001 19.3 1.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CCU98037.1 - 0.0057 15.9 0.9 0.0099 15.1 0.3 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 CCU98037.1 - 0.012 16.1 0.1 3.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 CCU98037.1 - 0.063 13.2 0.0 0.063 13.2 0.0 2.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CCU98037.1 - 0.084 12.2 4.7 0.78 9.0 0.3 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CCU98037.1 - 1.2 8.7 6.3 0.24 10.9 0.2 2.7 3 1 1 4 4 4 0 FAD dependent oxidoreductase WD40 PF00400.32 CCU98038.1 - 0.00098 19.9 0.0 0.0023 18.7 0.0 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat PQQ_3 PF13570.6 CCU98038.1 - 0.027 15.0 0.0 1.4 9.5 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain WD40 PF00400.32 CCU98039.1 - 0.01 16.7 0.2 1.4 9.9 0.1 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat CoaE PF01121.20 CCU98040.1 - 1.7e-53 181.0 0.2 2.1e-53 180.7 0.2 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 CCU98040.1 - 9.9e-06 26.1 0.0 5.6e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CCU98040.1 - 0.0042 17.3 0.2 0.016 15.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain CcmH PF03918.14 CCU98040.1 - 0.048 13.0 0.1 0.093 12.0 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein AAA_28 PF13521.6 CCU98040.1 - 0.086 13.1 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TFIID_20kDa PF03847.13 CCU98041.1 - 8.8e-33 112.6 0.3 1.6e-32 111.8 0.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 CCU98041.1 - 0.0035 17.6 0.0 0.0095 16.2 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MTS PF05175.14 CCU98042.1 - 4.4e-05 23.1 0.0 0.0028 17.2 0.0 2.0 2 0 0 2 2 2 2 Methyltransferase small domain Glyoxalase_4 PF13669.6 CCU98042.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UPF0020 PF01170.18 CCU98042.1 - 0.17 11.5 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 CBF PF03914.17 CCU98043.1 - 1.5e-24 86.9 0.0 3.4e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 CBF/Mak21 family ANAPC4_WD40 PF12894.7 CCU98045.1 - 0.00036 20.8 0.0 4.8 7.6 0.0 4.7 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCU98045.1 - 0.0029 18.4 0.1 12 6.9 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat Hira PF07569.11 CCU98045.1 - 0.041 13.6 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split PQQ PF01011.21 CCU98045.1 - 0.14 12.1 0.0 0.47 10.5 0.0 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat Porphobil_deam PF01379.20 CCU98046.1 - 2e-67 226.6 0.0 3.8e-67 225.8 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CCU98046.1 - 1.4e-14 54.2 0.1 7.8e-09 35.8 0.1 2.5 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain PI3_PI4_kinase PF00454.27 CCU98047.1 - 1.6e-51 175.6 0.0 4.3e-51 174.1 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 CCU98047.1 - 1.6e-18 66.5 0.0 1.1e-17 63.8 0.0 2.6 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.23 CCU98047.1 - 2.1e-17 63.3 0.6 5e-17 62.1 0.6 1.6 1 1 0 1 1 1 1 FAT domain FATC PF02260.20 CCU98047.1 - 2.1e-08 33.8 0.5 6.5e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 FATC domain Tnp_DNA_bind PF14706.6 CCU98047.1 - 0.28 11.0 2.9 0.63 9.9 0.0 3.2 4 0 0 4 4 4 0 Transposase DNA-binding TPR_12 PF13424.6 CCU98047.1 - 0.48 10.7 3.0 7 7.0 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CCU98047.1 - 1.7 8.8 9.5 0.046 13.9 1.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Oxysterol_BP PF01237.18 CCU98048.1 - 1.8e-62 211.3 0.2 4.9e-55 186.9 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein WD40 PF00400.32 CCU98049.1 - 1.2e-47 158.9 34.3 3.6e-05 24.4 0.0 12.2 12 1 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU98049.1 - 9.7e-21 73.9 0.6 0.0004 20.6 0.0 9.3 4 3 4 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CCU98049.1 - 1.8e-20 73.2 1.1 3.3e-20 72.4 1.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 CCU98049.1 - 5e-06 25.7 0.0 0.098 11.6 0.0 4.8 4 2 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CCU98049.1 - 4.8e-05 22.2 0.1 0.012 14.3 0.0 3.5 4 0 0 4 4 4 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CCU98049.1 - 6.8e-05 21.9 3.4 0.14 11.0 0.1 3.1 3 1 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Utp13 PF08625.11 CCU98049.1 - 0.004 17.1 0.1 0.013 15.4 0.1 1.8 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.11 CCU98049.1 - 0.023 13.5 0.0 10 4.7 0.0 3.2 3 0 0 3 3 3 0 Nup133 N terminal like Hira PF07569.11 CCU98049.1 - 0.052 13.3 0.0 5.6 6.6 0.0 2.9 2 0 0 2 2 2 0 TUP1-like enhancer of split WD40_like PF17005.5 CCU98049.1 - 0.25 10.6 0.0 50 3.1 0.0 3.1 3 0 0 3 3 3 0 WD40-like domain PQQ_3 PF13570.6 CCU98049.1 - 0.49 10.9 6.8 8 7.1 0.0 5.5 6 0 0 6 6 6 0 PQQ-like domain SurE PF01975.17 CCU98050.1 - 7.2e-31 107.5 0.0 9e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Ribosomal_S8e PF01201.22 CCU98051.1 - 1.2e-54 184.3 0.4 1.3e-54 184.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e bZIP_1 PF00170.21 CCU98052.1 - 2.3e-07 30.8 13.3 3.4e-07 30.3 10.8 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CCU98052.1 - 4e-06 26.8 11.8 7.5e-05 22.7 8.5 2.3 1 1 1 2 2 2 2 Basic region leucine zipper CENP-F_leu_zip PF10473.9 CCU98052.1 - 0.026 14.5 11.7 0.04 13.9 11.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2730 PF10805.8 CCU98052.1 - 0.096 12.8 2.7 0.16 12.0 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF724 PF05266.14 CCU98052.1 - 0.88 9.4 8.8 0.5 10.2 6.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) RabGAP-TBC PF00566.18 CCU98053.1 - 2.2e-58 197.4 0.4 2.2e-58 197.4 0.4 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 CCU98053.1 - 0.0034 17.5 4.6 0.0034 17.5 4.6 2.5 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 SurA_N_3 PF13624.6 CCU98053.1 - 0.3 10.9 5.2 2.5 7.8 5.5 2.2 2 0 0 2 2 2 0 SurA N-terminal domain RasGAP_C PF03836.15 CCU98053.1 - 1.2 9.3 8.7 0.064 13.4 3.1 1.7 2 0 0 2 2 2 0 RasGAP C-terminus Oxysterol_BP PF01237.18 CCU98054.1 - 3.9e-115 384.6 0.0 1.6e-114 382.6 0.0 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein Dopey_N PF04118.14 CCU98055.1 - 1.5e-104 349.4 0.0 7.2e-103 343.9 0.0 2.6 2 0 0 2 2 2 2 Dopey, N-terminal Exo84_C PF16528.5 CCU98056.1 - 3.4e-47 160.9 0.0 7.6e-47 159.8 0.0 1.6 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CCU98056.1 - 1.8e-14 53.6 0.5 3.7e-14 52.6 0.5 1.5 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 CCU98056.1 - 9.4e-07 29.0 0.3 2.3e-06 27.7 0.3 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 EXS PF03124.14 CCU98057.1 - 3.9e-90 302.5 28.2 5.2e-90 302.1 28.2 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CCU98057.1 - 1.2e-32 114.3 6.8 2.2e-32 113.4 6.8 1.3 1 0 0 1 1 1 1 SPX domain XTBD PF11952.8 CCU98057.1 - 0.017 14.9 0.1 0.079 12.7 0.1 2.1 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD DUF5489 PF17592.2 CCU98057.1 - 0.047 14.2 0.1 0.11 13.0 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5489) FTA4 PF13093.6 CCU98057.1 - 0.18 11.7 4.3 0.28 11.0 0.7 2.3 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Ribosomal_S15 PF00312.22 CCU98058.1 - 5.2e-23 81.1 0.0 1.1e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 SHQ1 PF04925.15 CCU98059.1 - 3.9e-25 88.4 0.0 6.3e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein WD40 PF00400.32 CCU98060.1 - 2.8e-20 72.2 9.7 0.00048 20.9 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CCU98060.1 - 0.086 11.8 0.3 9.2 5.1 0.0 2.9 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_hydro_18 PF00704.28 CCU98061.1 - 4.4e-75 253.3 0.2 1.9e-49 169.1 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 WWE PF02825.20 CCU98061.1 - 0.077 13.6 0.9 5.5 7.7 0.0 2.5 2 0 0 2 2 2 0 WWE domain DUF726 PF05277.12 CCU98062.1 - 1.1e-117 392.8 0.4 1.5e-117 392.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.20 CCU98062.1 - 0.0062 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold SRP14 PF02290.15 CCU98063.1 - 2.1e-21 76.1 0.0 3.7e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Tn7_Tnp_TnsA_N PF08722.11 CCU98063.1 - 0.0096 16.1 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 TnsA endonuclease N terminal Mem_trans PF03547.18 CCU98064.1 - 2.5e-27 95.3 1.9 7.3e-27 93.8 1.9 1.8 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.25 CCU98065.1 - 4.1e-35 121.4 0.0 6.4e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98065.1 - 1.4e-25 90.1 0.0 1.9e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCU98065.1 - 0.0099 15.2 0.1 0.023 14.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CCU98065.1 - 0.01 14.6 0.0 0.024 13.4 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 CCU98065.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Arm PF00514.23 CCU98066.1 - 0.044 13.8 0.0 0.044 13.8 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CCU98066.1 - 3.7 8.1 10.8 6 7.4 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat TPR_2 PF07719.17 CCU98068.1 - 4.8e-12 45.0 9.4 0.00018 21.4 0.5 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CCU98068.1 - 1.4e-10 41.1 9.1 0.0055 17.4 0.6 4.9 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 CCU98068.1 - 8.5e-10 38.1 8.8 9.6e-05 22.3 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CCU98068.1 - 9.2e-10 39.0 3.6 7.7e-05 23.3 0.1 2.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCU98068.1 - 6.2e-09 35.6 0.5 0.0021 18.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCU98068.1 - 7.5e-09 35.1 3.3 0.0042 16.9 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCU98068.1 - 4.8e-08 33.4 7.1 8.1e-05 23.1 0.3 4.3 3 2 1 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CCU98068.1 - 6.8e-08 32.7 3.8 0.12 13.0 0.1 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CCU98068.1 - 6.8e-06 26.1 0.9 0.0013 18.9 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCU98068.1 - 0.00012 21.9 4.2 0.34 11.0 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCU98068.1 - 0.00015 21.9 3.1 0.0017 18.5 1.0 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CCU98068.1 - 0.0006 20.0 10.8 2.7 8.4 0.0 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 CCU98068.1 - 0.0011 18.2 1.7 0.0041 16.4 0.3 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.10 CCU98068.1 - 0.0037 16.3 0.1 0.0049 15.9 0.1 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 CCU98068.1 - 0.0044 17.5 6.8 3.7 8.4 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 CCU98068.1 - 0.035 13.8 0.1 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 CCU98068.1 - 0.039 14.3 0.1 0.19 12.1 0.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CCU98068.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 DUF3808 PF10300.9 CCU98068.1 - 0.05 12.3 0.6 0.2 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) NARP1 PF12569.8 CCU98068.1 - 0.11 11.4 0.6 1.2 7.9 0.0 2.0 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 Metallophos PF00149.28 CCU98069.1 - 3.2e-39 135.6 0.0 4.2e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCU98069.1 - 1.2e-14 54.4 0.0 3.1e-14 53.1 0.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain CLP1_P PF16575.5 CCU98070.1 - 3.6e-26 92.1 0.1 1.5e-20 73.8 0.0 2.8 2 1 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CCU98070.1 - 1.9e-23 82.5 0.0 2.9e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CCU98070.1 - 1e-14 55.0 0.0 1.7e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.23 CCU98070.1 - 0.00016 21.7 0.0 0.041 14.0 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CCU98070.1 - 0.004 17.5 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Pro_CA PF00484.19 CCU98070.1 - 0.0076 16.5 0.1 0.022 15.1 0.0 1.7 2 0 0 2 2 2 1 Carbonic anhydrase Dynamin_N PF00350.23 CCU98070.1 - 0.0085 16.2 0.1 0.32 11.0 0.1 2.3 2 1 0 2 2 2 1 Dynamin family ABC_tran PF00005.27 CCU98070.1 - 0.016 15.7 0.0 0.039 14.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 CCU98070.1 - 0.024 14.9 0.1 0.087 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CCU98070.1 - 0.051 13.7 0.0 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CCU98070.1 - 0.053 13.4 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 CCU98070.1 - 0.058 12.7 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 CCU98070.1 - 0.18 11.5 0.1 1.2 9.0 0.0 2.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain GYF PF02213.16 CCU98071.1 - 1.8e-05 24.3 0.3 5.3e-05 22.8 0.3 1.9 1 0 0 1 1 1 1 GYF domain NDUFA12 PF05071.16 CCU98071.1 - 0.0009 20.0 2.0 0.0009 20.0 2.0 2.7 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Transketolase_N PF00456.21 CCU98072.1 - 1.1e-136 455.2 0.0 1.6e-136 454.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CCU98072.1 - 5.9e-43 146.6 0.0 1.1e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CCU98072.1 - 3.3e-13 49.6 0.0 7.4e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CCU98072.1 - 0.00019 20.7 0.1 0.0045 16.3 0.1 2.2 1 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 CCU98072.1 - 0.0047 15.9 0.0 0.0099 14.9 0.0 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component HMGL-like PF00682.19 CCU98073.1 - 1.6e-73 247.5 0.0 3.4e-73 246.4 0.0 1.6 2 0 0 2 2 2 1 HMGL-like TRAM_LAG1_CLN8 PF03798.16 CCU98073.1 - 1.5e-29 103.2 18.0 2.1e-29 102.7 18.0 1.2 1 0 0 1 1 1 1 TLC domain LeuA_dimer PF08502.10 CCU98073.1 - 1.2e-08 35.0 0.0 3.6e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain SET PF00856.28 CCU98074.1 - 0.00073 20.0 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 SET domain DUF2423 PF10338.9 CCU98074.1 - 0.062 13.5 0.1 2.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) Pex19 PF04614.12 CCU98075.1 - 2.6e-65 220.6 4.4 3.3e-65 220.3 4.4 1.1 1 0 0 1 1 1 1 Pex19 protein family DUF4456 PF14644.6 CCU98075.1 - 0.061 13.0 0.3 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) DHHC PF01529.20 CCU98076.1 - 2e-31 108.8 9.6 2e-31 108.8 9.6 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Myosin_head PF00063.21 CCU98077.1 - 1.3e-237 790.4 0.0 1.7e-237 789.9 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CCU98077.1 - 3e-46 157.4 0.0 4.7e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 CCU98077.1 - 4.1e-12 45.8 0.7 1.7e-11 43.8 0.4 2.3 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 CCU98077.1 - 8.8e-12 44.5 0.2 1.8e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CCU98077.1 - 7.4e-08 32.0 0.0 2.5e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Hpr_kinase_C PF07475.12 CCU98077.1 - 0.00075 19.1 0.4 1 8.9 0.0 2.5 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain SH3_3 PF08239.11 CCU98077.1 - 0.00084 19.6 1.5 0.0016 18.7 0.7 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain AAA_22 PF13401.6 CCU98077.1 - 0.026 14.8 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain PurS PF02700.14 CCU98077.1 - 0.054 13.7 0.0 11 6.3 0.0 3.1 3 0 0 3 3 3 0 Phosphoribosylformylglycinamidine (FGAM) synthase NACHT PF05729.12 CCU98077.1 - 0.093 12.6 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 CCU98077.1 - 0.095 13.1 1.0 0.25 11.7 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 CCU98077.1 - 0.2 11.7 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IQ PF00612.27 CCU98077.1 - 2.7 8.0 15.3 0.37 10.7 4.7 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif Abhydrolase_2 PF02230.16 CCU98078.1 - 1.8e-50 171.8 0.0 2.1e-50 171.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CCU98078.1 - 7.4e-07 28.7 0.5 0.0076 15.5 0.2 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCU98078.1 - 1.8e-06 28.7 1.5 2.1e-06 28.5 1.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CCU98078.1 - 1.6e-05 24.7 0.1 0.0018 17.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 CCU98078.1 - 0.00022 20.9 0.4 0.00045 20.0 0.3 1.6 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.13 CCU98078.1 - 0.00066 19.4 0.0 0.0018 17.9 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase_phd PF10503.9 CCU98078.1 - 0.00092 18.8 0.0 0.0062 16.0 0.0 2.1 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 CCU98078.1 - 0.013 15.3 0.1 0.033 14.1 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 CCU98078.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Fungal_trans PF04082.18 CCU98079.1 - 1.2e-13 50.7 0.9 2.6e-13 49.6 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCU98079.1 - 0.0091 16.1 4.8 0.018 15.1 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L34e PF01199.18 CCU98080.1 - 1.2e-41 140.9 5.6 1.6e-41 140.5 5.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.6 CCU98080.1 - 0.0078 16.2 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c RAG1_imp_bd PF12560.8 CCU98080.1 - 0.13 11.7 2.0 0.15 11.6 2.0 1.2 1 0 0 1 1 1 0 RAG1 importin binding Ribosomal_L6 PF00347.23 CCU98081.1 - 2.8e-20 72.8 0.0 2.1e-11 44.3 0.0 2.7 2 0 0 2 2 2 2 Ribosomal protein L6 NAD_kinase PF01513.21 CCU98082.1 - 1.6e-41 142.4 0.0 2.5e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase SKG6 PF08693.10 CCU98083.1 - 6.7e-05 22.2 0.4 0.00012 21.4 0.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 CCU98083.1 - 0.00062 20.2 0.2 0.0017 18.9 0.0 1.7 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Syndecan PF01034.20 CCU98083.1 - 0.012 15.6 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 CCU98083.1 - 0.059 13.1 0.1 0.094 12.5 0.1 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Herpes_gE PF02480.16 CCU98083.1 - 0.1 11.4 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4328 PF14219.6 CCU98083.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) PTP_tm PF18861.1 CCU98083.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J GST_N_3 PF13417.6 CCU98084.1 - 8.3e-11 42.2 0.0 2.1e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CCU98084.1 - 1.1e-09 38.5 0.0 2.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CCU98084.1 - 7.1e-05 22.9 0.0 0.00059 20.0 0.0 2.3 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CCU98084.1 - 0.00011 22.3 0.0 0.00027 21.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CCU98084.1 - 0.00018 21.8 0.0 0.00032 21.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCU98084.1 - 0.026 14.5 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SMI1_KNR4 PF09346.10 CCU98086.1 - 2.5e-21 76.5 0.0 4.6e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Glyco_hydro_63 PF03200.16 CCU98087.1 - 4e-157 523.9 0.1 1.8e-155 518.5 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CCU98087.1 - 1.8e-54 185.2 0.2 9.3e-54 182.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 CCU98087.1 - 9.3e-05 21.4 0.1 0.00014 20.8 0.1 1.3 1 0 0 1 1 1 1 Trehalase SOG2 PF10428.9 CCU98088.1 - 2.1e-74 251.6 1.3 1.7e-50 172.7 1.7 2.2 1 1 1 2 2 2 2 RAM signalling pathway protein CorA PF01544.18 CCU98088.1 - 0.025 13.9 0.3 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SH2_2 PF14633.6 CCU98089.1 - 1.1e-75 253.8 0.0 1.9e-75 253.0 0.0 1.4 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.6 CCU98089.1 - 6.4e-23 81.2 0.0 3e-22 79.0 0.0 2.1 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 CCU98089.1 - 6.9e-20 71.3 0.0 1.8e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 CCU98089.1 - 7.1e-20 71.6 0.0 1.9e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 CCU98089.1 - 4.5e-12 46.4 23.1 4.5e-12 46.4 23.1 3.4 2 1 1 3 3 3 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 CCU98089.1 - 0.00025 21.9 0.1 0.0011 19.8 0.1 2.3 1 0 0 1 1 1 1 HHH domain SH2 PF00017.24 CCU98089.1 - 0.00045 20.3 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain S1 PF00575.23 CCU98089.1 - 0.0085 16.4 0.0 0.038 14.3 0.0 2.2 2 0 0 2 2 2 1 S1 RNA binding domain Tex_N PF09371.10 CCU98089.1 - 0.02 14.5 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 0 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 CCU98089.1 - 0.16 12.5 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Tex protein YqgF-like domain SET PF00856.28 CCU98090.1 - 2.3e-10 41.1 0.0 4.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 SET domain AAA PF00004.29 CCU98091.1 - 2.8e-45 154.0 0.1 1.5e-44 151.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CCU98091.1 - 7.4e-09 35.4 0.2 4.7e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CCU98091.1 - 1.9e-08 34.4 0.1 5.8e-08 32.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCU98091.1 - 1.2e-07 32.3 0.2 3e-05 24.5 0.0 2.8 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 CCU98091.1 - 1.3e-07 31.9 0.1 3.2e-07 30.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 CCU98091.1 - 3.9e-07 29.8 0.0 8.4e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain DUF815 PF05673.13 CCU98091.1 - 8e-06 25.2 0.3 1.9e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CCU98091.1 - 0.00015 22.0 2.0 0.0098 16.2 0.1 3.0 3 1 1 4 4 2 1 AAA domain RuvB_N PF05496.12 CCU98091.1 - 0.00023 20.9 0.0 0.00059 19.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 CCU98091.1 - 0.00036 20.3 0.0 0.00097 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CCU98091.1 - 0.00061 20.1 0.1 0.002 18.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 CCU98091.1 - 0.0013 18.6 0.2 0.0053 16.7 0.0 2.1 3 0 0 3 3 2 1 NTPase AAA_18 PF13238.6 CCU98091.1 - 0.0015 19.1 0.0 0.0056 17.2 0.0 2.0 3 0 0 3 3 1 1 AAA domain TsaE PF02367.17 CCU98091.1 - 0.0016 18.5 0.0 0.005 16.8 0.0 1.8 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CCU98091.1 - 0.0021 18.1 0.0 0.0056 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CCU98091.1 - 0.0022 18.4 0.0 0.0045 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 CCU98091.1 - 0.0036 16.9 0.1 0.021 14.4 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 CCU98091.1 - 0.004 17.3 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF3450 PF11932.8 CCU98091.1 - 0.0042 16.4 0.3 0.0071 15.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Mg_chelatase PF01078.21 CCU98091.1 - 0.0068 15.8 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CCU98091.1 - 0.0068 16.3 0.1 0.071 13.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_3 PF07726.11 CCU98091.1 - 0.0082 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 CCU98091.1 - 0.0086 16.0 0.5 0.37 10.7 0.0 2.7 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea TniB PF05621.11 CCU98091.1 - 0.0095 15.4 0.5 0.65 9.4 0.0 2.7 3 0 0 3 3 3 1 Bacterial TniB protein IstB_IS21 PF01695.17 CCU98091.1 - 0.012 15.4 0.0 0.032 14.0 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein TIP49 PF06068.13 CCU98091.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 CCU98091.1 - 0.019 14.7 0.1 0.041 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CCU98091.1 - 0.036 13.9 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 CCU98091.1 - 0.052 13.4 0.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial dnaA protein Prot_ATP_OB_N PF17758.1 CCU98091.1 - 0.056 13.1 0.2 0.72 9.5 0.0 2.6 3 0 0 3 3 3 0 Proteasomal ATPase OB N-terminal domain AAA_23 PF13476.6 CCU98091.1 - 0.062 13.8 0.4 0.75 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CCU98091.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CCU98091.1 - 0.066 12.8 0.8 0.24 10.9 0.1 2.0 2 1 0 3 3 3 0 AAA domain AFG1_ATPase PF03969.16 CCU98091.1 - 0.089 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase ATPase PF06745.13 CCU98091.1 - 0.093 12.1 0.2 0.52 9.6 0.0 2.3 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.26 CCU98091.1 - 0.1 12.3 0.2 1.4 8.6 0.0 2.6 3 1 0 3 3 3 0 Sigma-54 interaction domain AAA_29 PF13555.6 CCU98091.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 CCU98091.1 - 0.13 12.6 0.1 0.4 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CCU98091.1 - 0.17 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain HIP1_clath_bdg PF16515.5 CCU98091.1 - 0.51 11.0 4.2 1.2 9.8 2.6 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 P5CR_dimer PF14748.6 CCU98092.1 - 2.9e-37 127.1 4.3 3.9e-37 126.7 3.1 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CCU98092.1 - 6.4e-13 49.1 0.5 1.9e-10 41.2 0.5 2.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ATP-gua_Ptrans PF00217.19 CCU98092.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain ADIP PF11559.8 CCU98093.1 - 0.00068 19.8 13.6 0.00068 19.8 13.6 2.6 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.11 CCU98093.1 - 0.00093 18.2 21.5 0.0016 17.4 21.5 1.4 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 CCU98093.1 - 0.0013 18.8 25.9 0.023 14.7 14.9 2.4 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 CCU98093.1 - 0.0019 18.6 6.6 0.098 13.1 0.4 3.8 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 CCU98093.1 - 0.0053 16.1 6.3 0.0053 16.1 6.3 3.0 1 1 0 2 2 2 1 Protein of unknown function (DUF3450) Telomere_reg-2 PF10193.9 CCU98093.1 - 0.022 15.2 2.4 0.043 14.3 2.4 1.6 1 0 0 1 1 1 0 Telomere length regulation protein FPP PF05911.11 CCU98093.1 - 0.023 12.9 21.2 0.024 12.9 19.3 1.7 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF2353 PF09789.9 CCU98093.1 - 0.035 13.5 22.4 0.051 12.9 5.1 2.3 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF1319 PF07028.11 CCU98093.1 - 0.052 13.8 2.0 0.11 12.8 0.5 2.3 1 1 0 2 2 1 0 Protein of unknown function (DUF1319) Baculo_PEP_C PF04513.12 CCU98093.1 - 0.091 12.8 7.0 0.065 13.3 2.5 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CEP209_CC5 PF16574.5 CCU98093.1 - 0.1 12.8 19.8 0.24 11.6 2.8 3.6 2 1 1 3 3 3 0 Coiled-coil region of centrosome protein CE290 Tup_N PF08581.10 CCU98093.1 - 0.12 12.7 22.0 0.08 13.3 5.9 3.8 2 1 1 3 3 3 0 Tup N-terminal Syntaxin-6_N PF09177.11 CCU98093.1 - 0.13 12.8 15.6 3 8.5 3.4 3.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Spc7 PF08317.11 CCU98093.1 - 0.16 10.8 25.3 0.082 11.8 17.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 CCU98093.1 - 0.22 11.6 13.7 0.25 11.4 4.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.20 CCU98093.1 - 0.3 10.4 20.2 0.039 13.3 6.6 2.3 1 1 2 3 3 3 0 Tropomyosin RasGAP_C PF03836.15 CCU98093.1 - 0.31 11.2 12.9 0.029 14.5 6.1 2.4 1 1 0 2 2 2 0 RasGAP C-terminus Fib_alpha PF08702.10 CCU98093.1 - 0.35 11.1 9.4 0.061 13.5 2.8 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HAP1_N PF04849.13 CCU98093.1 - 0.36 10.0 29.2 75 2.4 29.2 2.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF4795 PF16043.5 CCU98093.1 - 0.58 9.7 18.9 3.7 7.1 10.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) THOC7 PF05615.13 CCU98093.1 - 0.6 10.4 21.8 2.1 8.6 6.1 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 APG6_N PF17675.1 CCU98093.1 - 0.73 10.4 29.0 2.7 8.5 12.8 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 CCU98093.1 - 0.75 9.9 14.7 0.17 11.9 4.4 3.3 2 2 1 3 3 3 0 BRE1 E3 ubiquitin ligase Macoilin PF09726.9 CCU98093.1 - 0.8 8.2 17.6 1.3 7.5 17.6 1.3 1 0 0 1 1 1 0 Macoilin family DUF4763 PF15960.5 CCU98093.1 - 0.81 8.9 25.2 0.78 9.0 10.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DUF812 PF05667.11 CCU98093.1 - 1 8.2 23.1 34 3.1 23.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Med9 PF07544.13 CCU98093.1 - 1.3 9.2 9.2 0.52 10.4 0.2 3.0 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.9 CCU98093.1 - 1.5 9.1 9.3 6.7 7.1 1.0 3.1 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 CCU98093.1 - 1.8 8.6 12.8 5.9 6.9 1.0 2.9 2 1 1 3 3 3 0 Laminin Domain II EMP24_GP25L PF01105.24 CCU98093.1 - 1.9 8.4 7.9 0.12 12.3 1.5 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Seryl_tRNA_N PF02403.22 CCU98093.1 - 2.6 8.3 13.0 0.58 10.4 1.7 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HAUS-augmin3 PF14932.6 CCU98093.1 - 2.7 7.5 27.9 12 5.4 11.6 2.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.6 CCU98093.1 - 3.1 7.6 24.0 6.1 6.6 2.6 2.9 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 CCU98093.1 - 3.6 6.9 20.3 1.7 7.9 2.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Snf7 PF03357.21 CCU98093.1 - 3.7 7.1 12.6 0.68 9.5 4.9 2.4 1 1 1 2 2 2 0 Snf7 DHR10 PF18595.1 CCU98093.1 - 3.9 7.6 36.6 1.8 8.6 8.2 3.6 2 1 0 3 3 2 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 CCU98093.1 - 4.4 7.8 6.5 3.7 8.0 0.0 3.8 4 1 0 4 4 3 0 Flagella accessory protein C (FlaC) DUF4618 PF15397.6 CCU98093.1 - 4.7 6.6 20.8 13 5.1 20.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) JIP_LZII PF16471.5 CCU98093.1 - 4.7 7.4 21.7 2.2 8.5 1.1 4.3 1 1 3 5 5 5 0 JNK-interacting protein leucine zipper II TMF_DNA_bd PF12329.8 CCU98093.1 - 6.2 6.9 18.4 0.51 10.4 0.5 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding AATF-Che1 PF13339.6 CCU98093.1 - 6.3 7.5 12.7 30 5.3 11.9 2.5 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor ATG16 PF08614.11 CCU98093.1 - 6.9 6.8 34.9 35 4.5 30.8 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 CCU98093.1 - 7.5 5.8 25.2 1.7 8.0 8.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 CCU98093.1 - 8.2 6.2 17.7 4.9 6.9 7.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF5320 PF17253.2 CCU98093.1 - 8.3 7.5 5.8 3.5 8.8 0.2 2.8 2 2 0 2 2 2 0 Family of unknown function (DUF5320) HIP1_clath_bdg PF16515.5 CCU98093.1 - 8.3 7.1 29.9 4.8 7.9 9.9 3.5 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FapA PF03961.13 CCU98093.1 - 8.9 4.8 11.2 2.8 6.5 4.0 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A AAA_13 PF13166.6 CCU98093.1 - 9.6 4.7 13.7 0.16 10.5 2.2 2.0 1 1 0 1 1 1 0 AAA domain DUF2730 PF10805.8 CCU98093.1 - 9.9 6.3 10.7 15 5.8 2.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DCB PF16213.5 CCU98094.1 - 2.8e-36 124.8 4.4 2.8e-36 124.8 4.4 2.5 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CCU98094.1 - 2.2e-26 92.7 2.0 2.2e-26 92.7 2.0 3.8 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 CCU98094.1 - 5.4e-08 31.5 2.5 2.4e-05 22.7 0.0 3.2 3 1 0 3 3 3 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 CCU98094.1 - 1.7e-05 24.6 0.1 0.00023 20.9 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) ptaRNA1_toxin PF12703.7 CCU98094.1 - 0.023 14.7 0.3 0.25 11.4 0.1 2.6 2 0 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system Ribosomal_L26 PF16906.5 CCU98095.1 - 1e-36 125.2 2.3 1.2e-36 125.0 2.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CCU98095.1 - 1.9e-07 30.8 0.5 1.9e-07 30.8 0.5 2.1 2 0 0 2 2 2 1 KOW motif Arf PF00025.21 CCU98096.1 - 6e-35 120.3 0.0 3.5e-34 117.8 0.0 1.8 1 1 1 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 CCU98096.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pkinase PF00069.25 CCU98097.1 - 1.3e-60 205.0 0.0 4.8e-60 203.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98097.1 - 3.4e-22 79.0 0.0 4.9e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU98097.1 - 0.00055 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCU98097.1 - 0.0027 17.7 0.1 0.0095 15.9 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CCU98097.1 - 0.033 13.8 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 CCU98097.1 - 0.072 12.7 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 CCU98097.1 - 0.098 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UreD PF01774.17 CCU98098.1 - 3.6e-63 213.3 0.0 4.1e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein Fcf1 PF04900.12 CCU98099.1 - 1.1e-36 125.1 1.6 2.1e-36 124.3 1.6 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 CCU98099.1 - 6.1e-13 49.1 0.3 6.4e-12 45.8 0.0 2.1 2 1 0 2 2 2 1 PIN like domain SUI1 PF01253.22 CCU98100.1 - 3.4e-26 91.6 0.3 5.7e-26 90.9 0.1 1.4 1 1 0 1 1 1 1 Translation initiation factor SUI1 rRNA_processing PF08524.11 CCU98101.1 - 1.4e-08 34.9 5.6 2.8e-08 33.9 5.6 1.5 1 1 0 1 1 1 1 rRNA processing Cep57_MT_bd PF06657.13 CCU98102.1 - 6.6e-11 42.5 12.6 9.8e-09 35.6 2.4 4.3 3 1 1 4 4 4 2 Centrosome microtubule-binding domain of Cep57 SlyX PF04102.12 CCU98102.1 - 0.0061 17.1 5.4 0.083 13.5 0.0 4.5 4 1 0 5 5 5 1 SlyX DNA_meth_N PF18284.1 CCU98102.1 - 0.0076 16.1 0.3 0.018 15.0 0.3 1.6 1 0 0 1 1 1 1 DNA methylase N-terminal domain BLOC1_2 PF10046.9 CCU98102.1 - 0.02 15.2 0.3 15 6.0 0.0 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dam1 PF08653.10 CCU98102.1 - 0.025 14.4 2.5 17 5.3 0.0 4.1 4 0 0 4 4 4 0 DASH complex subunit Dam1 HemX PF04375.14 CCU98102.1 - 0.04 13.2 0.4 0.04 13.2 0.4 2.5 2 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DHR10 PF18595.1 CCU98102.1 - 0.052 13.6 0.6 0.052 13.6 0.6 2.9 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain HSBP1 PF06825.12 CCU98102.1 - 0.06 13.2 1.0 0.26 11.1 0.5 2.4 2 1 0 2 2 2 0 Heat shock factor binding protein 1 DUF2767 PF10965.8 CCU98102.1 - 0.061 13.3 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) DUF241 PF03087.14 CCU98102.1 - 0.086 12.7 1.6 2.2 8.0 0.1 3.3 3 1 0 3 3 3 0 Arabidopsis protein of unknown function FlxA PF14282.6 CCU98102.1 - 0.3 11.1 2.9 1.1 9.3 0.4 2.7 3 0 0 3 3 3 0 FlxA-like protein DUF1043 PF06295.12 CCU98102.1 - 0.47 10.5 4.5 0.45 10.5 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Phage_GPO PF05929.11 CCU98102.1 - 1 8.9 7.3 0.33 10.5 0.3 2.6 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase ADIP PF11559.8 CCU98102.1 - 1.1 9.4 10.9 1.5 8.9 0.3 3.6 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 CCU98102.1 - 4 6.7 8.2 2.7 7.2 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 CCU98102.1 - 4.4 7.5 7.9 32 4.8 0.0 3.5 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 CCU98102.1 - 9.7 5.5 8.1 2.4 7.5 0.1 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Glycos_transf_1 PF00534.20 CCU98103.1 - 3.4e-28 98.3 0.0 1.5e-27 96.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCU98103.1 - 3.1e-14 53.3 3.1 8.6e-13 48.6 3.1 2.4 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CCU98103.1 - 1.3e-12 48.3 0.1 2.2e-11 44.3 0.1 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CCU98103.1 - 4.6e-06 27.2 3.9 4.6e-06 27.2 3.9 2.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CCU98103.1 - 0.00016 22.0 0.1 0.00055 20.3 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 CCU98103.1 - 0.00041 20.5 0.0 0.0018 18.4 0.0 1.9 1 1 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Mito_carr PF00153.27 CCU98104.1 - 1e-19 70.2 0.9 2.1e-07 30.8 0.0 5.0 4 1 0 4 4 4 4 Mitochondrial carrier protein ANAPC_CDC26 PF10471.9 CCU98104.1 - 0.00056 20.7 0.2 0.0011 19.8 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Methyltr_RsmB-F PF01189.17 CCU98105.1 - 2.1e-34 118.9 0.0 2.8e-32 112.0 0.0 2.7 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CCU98105.1 - 0.0011 19.2 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DnaJ_C PF01556.18 CCU98106.1 - 1.4e-33 116.1 0.0 1.8e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCU98106.1 - 7.7e-24 83.6 2.4 1.2e-23 83.0 2.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCU98106.1 - 3e-11 43.5 18.6 3e-11 43.5 17.1 1.8 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 CCU98106.1 - 0.68 9.9 18.6 0.57 10.2 5.4 3.5 1 1 3 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CCU98106.1 - 1.8 8.6 6.4 11 6.1 6.4 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LMWPc PF01451.21 CCU98107.1 - 3.8e-26 92.2 0.0 4.5e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Sec1 PF00995.23 CCU98108.1 - 1.5e-116 391.0 0.0 1.6e-116 390.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family 4HBT_3 PF13622.6 CCU98109.1 - 3.1e-19 70.2 1.2 3.1e-19 70.2 1.2 4.1 2 1 0 3 3 3 1 Thioesterase-like superfamily GYF PF02213.16 CCU98109.1 - 2.8e-14 52.5 0.1 6.5e-14 51.3 0.1 1.7 1 0 0 1 1 1 1 GYF domain Acyl_CoA_thio PF02551.15 CCU98109.1 - 0.00046 20.0 0.0 0.0025 17.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA thioesterase Hist_deacetyl PF00850.19 CCU98110.1 - 1.7e-84 284.0 0.0 2.4e-84 283.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ATP-synt_F PF01990.17 CCU98111.1 - 8.7e-28 96.5 0.1 1e-27 96.3 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PTH2 PF01981.16 CCU98112.1 - 3.3e-25 88.6 1.0 7.1e-25 87.6 1.0 1.6 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF3515 PF12028.8 CCU98112.1 - 0.026 14.2 0.0 0.14 11.9 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3515) TPR_11 PF13414.6 CCU98112.1 - 0.048 13.4 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 TPR repeat NUDIX PF00293.28 CCU98113.1 - 9.3e-16 58.1 0.0 2.5e-15 56.7 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain DCP2 PF05026.13 CCU98113.1 - 6.9e-08 32.7 0.0 2.5e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Dcp2, box A domain BATS PF06968.13 CCU98114.1 - 9.2e-19 67.4 0.1 3.2e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 CCU98114.1 - 1.8e-15 57.7 0.1 3.9e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily DUF900 PF05990.12 CCU98115.1 - 0.039 13.5 0.0 0.38 10.2 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PPR_2 PF13041.6 CCU98117.1 - 1.3e-08 34.9 0.0 0.032 14.4 0.0 5.3 4 1 0 4 4 4 3 PPR repeat family PPR PF01535.20 CCU98117.1 - 0.00091 19.3 0.1 9 6.8 0.0 5.0 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 CCU98117.1 - 0.0018 18.3 0.0 0.39 10.8 0.0 3.8 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_long PF17177.4 CCU98117.1 - 0.048 13.0 0.4 3.6e+02 0.4 0.0 3.5 3 1 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP EXOSC1 PF10447.9 CCU98118.1 - 5.7e-24 84.8 0.4 1.2e-22 80.6 0.4 2.1 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 CCU98118.1 - 0.0063 16.3 0.2 0.022 14.6 0.2 2.0 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region LTV PF04180.14 CCU98119.1 - 3.1e-62 211.5 0.6 3.1e-62 211.5 0.6 2.1 2 0 0 2 2 2 1 Low temperature viability protein NAM-associated PF14303.6 CCU98119.1 - 2.2 8.9 10.7 5 7.8 10.7 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain WES_acyltransf PF03007.16 CCU98120.1 - 4.7e-14 52.8 0.1 7.3e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 CCU98120.1 - 1.7e-07 31.3 0.0 3.9e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1298) 2-oxoacid_dh PF00198.23 CCU98121.1 - 7.5e-78 261.2 0.4 1e-77 260.7 0.4 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CCU98121.1 - 1.3e-18 66.6 0.4 2.6e-18 65.6 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CCU98121.1 - 1.7e-12 47.4 0.2 3.8e-12 46.3 0.2 1.6 1 0 0 1 1 1 1 e3 binding domain RNA_pol_Rpc4 PF05132.14 CCU98121.1 - 0.0021 18.5 3.1 0.0021 18.5 3.1 1.7 2 0 0 2 2 2 1 RNA polymerase III RPC4 CDC45 PF02724.14 CCU98121.1 - 0.0036 15.7 1.7 0.0047 15.3 1.7 1.2 1 0 0 1 1 1 1 CDC45-like protein Presenilin PF01080.17 CCU98121.1 - 0.014 14.2 1.9 0.021 13.6 1.9 1.3 1 0 0 1 1 1 0 Presenilin SspB PF04386.13 CCU98121.1 - 0.021 14.7 8.2 4.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Stringent starvation protein B GAGA_bind PF06217.12 CCU98121.1 - 0.079 13.2 2.0 0.13 12.5 2.0 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family ABATE PF07336.11 CCU98121.1 - 0.1 13.3 1.4 0.26 12.0 0.2 2.4 2 0 0 2 2 2 0 Putative stress-induced transcription regulator RR_TM4-6 PF06459.12 CCU98121.1 - 0.78 9.5 11.5 0.36 10.6 8.7 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 CCU98121.1 - 1.4 7.6 4.8 2 7.1 4.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 CCU98121.1 - 2.5 6.1 3.8 3.3 5.7 3.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spore_coat_CotO PF14153.6 CCU98121.1 - 2.8 7.8 13.7 0.88 9.5 10.1 1.8 2 0 0 2 2 2 0 Spore coat protein CotO RPN2_C PF18004.1 CCU98121.1 - 5.1 7.0 15.3 0.33 10.8 9.8 1.9 3 0 0 3 3 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CPSF100_C PF13299.6 CCU98121.1 - 7 6.8 9.9 2.5 8.3 6.8 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Tim54 PF11711.8 CCU98121.1 - 10 4.8 12.2 17 4.0 12.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RMI1_N PF08585.12 CCU98122.1 - 1.8e-24 86.7 0.1 1.4e-23 83.8 0.1 2.1 1 1 0 1 1 1 1 RecQ mediated genome instability protein BRF1 PF07741.13 CCU98123.1 - 1.1 9.7 6.0 3.6 8.0 3.1 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain FAM60A PF15396.6 CCU98123.1 - 1.6 8.7 8.4 2.6 8.0 8.4 1.4 1 1 0 1 1 1 0 Protein Family FAM60A Mitofilin PF09731.9 CCU98124.1 - 2.5 6.9 5.3 5.1 5.8 5.3 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RNA_pol_Rpb2_6 PF00562.28 CCU98125.1 - 3.3e-124 414.9 0.1 6.1e-124 414.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CCU98125.1 - 2e-63 213.6 0.0 3.1e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CCU98125.1 - 8.6e-49 165.8 0.0 1.6e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CCU98125.1 - 3.6e-31 107.4 0.2 1e-30 105.9 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CCU98125.1 - 2.4e-25 88.6 0.2 7.2e-25 87.1 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CCU98125.1 - 2.8e-25 88.3 0.1 6.6e-25 87.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CCU98125.1 - 3.8e-21 75.4 0.2 1.2e-20 73.9 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 CWC25 PF12542.8 CCU98126.1 - 1.7e-23 83.5 1.8 1.7e-23 83.5 1.8 4.0 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 CCU98126.1 - 2.5e-14 53.2 18.0 2.5e-14 53.2 18.0 4.3 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR MFS_1 PF07690.16 CCU98127.1 - 2.3e-31 109.0 29.9 3e-31 108.7 29.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Lung_7-TM_R PF06814.13 CCU98128.1 - 1.9e-41 142.3 26.1 4.7e-41 140.9 26.1 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF4131 PF13567.6 CCU98128.1 - 9.4 5.9 13.8 0.28 10.8 0.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Homeobox_KN PF05920.11 CCU98130.1 - 1.3e-13 50.5 0.2 4e-13 49.0 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain Ustilago_mating PF05722.12 CCU98130.1 - 2.8e-05 23.8 0.6 6.4e-05 22.6 0.6 1.7 1 1 0 1 1 1 1 Ustilago B locus mating-type protein Arg_repressor PF01316.21 CCU98130.1 - 0.0044 16.7 0.2 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 Arginine repressor, DNA binding domain Homeodomain PF00046.29 CCU98131.1 - 1.7e-07 31.0 0.2 8.9e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CCU98131.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain AA_permease_2 PF13520.6 CCU98132.1 - 1.1e-67 228.8 37.0 1.1e-67 228.8 37.0 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCU98132.1 - 8.6e-16 57.6 31.0 8.6e-16 57.6 31.0 1.7 2 0 0 2 2 2 1 Amino acid permease SUR7 PF06687.12 CCU98132.1 - 0.026 14.1 0.0 0.026 14.1 0.0 2.9 1 1 1 3 3 3 0 SUR7/PalI family Phage_holin_3_6 PF07332.11 CCU98132.1 - 0.26 11.3 0.1 0.26 11.3 0.1 3.7 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1077 PF06417.12 CCU98132.1 - 1.7 8.7 4.4 6 6.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1077) Aldo_ket_red PF00248.21 CCU98133.1 - 4e-46 157.5 0.0 4.5e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SpoOE-like PF09388.10 CCU98133.1 - 0.25 11.3 0.6 7.6 6.5 0.0 2.8 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein HA2 PF04408.23 CCU98134.1 - 2.3e-16 60.0 0.1 2.3e-16 60.0 0.1 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCU98134.1 - 3.8e-13 49.8 0.0 8.9e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCU98134.1 - 2.8e-10 40.3 0.1 7.4e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 CCU98134.1 - 1.3e-09 38.2 0.0 3.2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 CCU98134.1 - 3.9e-07 30.4 1.0 6.8e-06 26.4 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.6 CCU98134.1 - 0.0026 18.1 0.0 0.027 14.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CCU98134.1 - 0.012 16.2 0.9 0.08 13.5 0.0 2.8 3 0 0 3 3 3 0 ABC transporter T2SSE PF00437.20 CCU98134.1 - 0.034 13.2 0.0 0.11 11.5 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 CCU98134.1 - 0.058 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 KaiC Lar_N PF09861.9 CCU98134.1 - 0.12 11.5 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Lactate racemase N-terminal domain AAA_16 PF13191.6 CCU98134.1 - 0.36 11.2 0.0 0.36 11.2 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 CCU98134.1 - 0.38 11.2 2.6 12 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain CS PF04969.16 CCU98136.1 - 0.00014 22.8 0.0 0.00042 21.3 0.0 1.8 2 0 0 2 2 2 1 CS domain Acetyltransf_8 PF13523.6 CCU98137.1 - 5.4e-45 152.6 0.2 9.5e-45 151.8 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain K_oxygenase PF13434.6 CCU98138.1 - 1.5e-93 313.7 0.0 1.9e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CCU98138.1 - 0.00054 20.0 0.0 0.003 17.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Sec3_C PF09763.9 CCU98139.1 - 4.7e-131 438.5 0.0 1.5e-77 261.6 0.0 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec3 Lactamase_B_2 PF12706.7 CCU98139.1 - 2.6e-23 82.6 0.0 1.1e-22 80.5 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Sec3-PIP2_bind PF15277.6 CCU98139.1 - 1.3e-07 31.6 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Lactamase_B_3 PF13483.6 CCU98139.1 - 0.00016 21.6 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ald_Xan_dh_C2 PF02738.18 CCU98139.1 - 0.1 11.0 3.2 0.19 10.1 3.2 1.3 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Rav1p_C PF12234.8 CCU98141.1 - 1.3e-97 327.8 9.4 4.5e-88 296.3 1.6 2.1 2 0 0 2 2 2 2 RAVE protein 1 C terminal Nucleoporin_N PF08801.11 CCU98141.1 - 0.016 13.9 0.0 2.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like Aminotran_1_2 PF00155.21 CCU98142.1 - 3.9e-92 309.2 0.0 4.5e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HHH_8 PF14716.6 CCU98143.1 - 7.3e-12 45.5 0.0 3.4e-09 36.9 0.0 2.7 2 1 1 3 3 3 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CCU98143.1 - 1.1e-11 44.3 0.0 6.9e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 CCU98143.1 - 1.8e-08 34.9 0.0 0.0019 18.8 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_2 PF12826.7 CCU98143.1 - 1.3e-06 28.4 0.0 1.2e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.23 CCU98143.1 - 2.3e-06 27.2 0.0 0.00032 20.4 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif Cdd1 PF11731.8 CCU98143.1 - 2.3e-05 24.5 0.0 0.012 15.9 0.0 2.3 1 1 0 2 2 2 2 Pathogenicity locus HHH_3 PF12836.7 CCU98143.1 - 0.00044 20.4 0.0 0.018 15.3 0.0 2.4 1 1 0 1 1 1 1 Helix-hairpin-helix motif DUF3701 PF12482.8 CCU98143.1 - 0.0023 17.9 0.3 1.2 9.3 0.1 2.7 2 1 0 2 2 2 2 Phage integrase protein Peptidase_M28 PF04389.17 CCU98144.1 - 1.8e-26 93.1 0.0 2.4e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CCU98144.1 - 2.9e-09 36.9 0.0 4.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 S1 PF00575.23 CCU98145.1 - 5.3e-42 142.0 14.0 4.9e-15 55.6 0.2 9.1 9 0 0 9 9 9 6 S1 RNA binding domain TPR_19 PF14559.6 CCU98145.1 - 1.6e-06 28.5 0.0 0.73 10.4 0.0 4.5 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCU98145.1 - 1.5e-05 25.4 9.9 0.13 13.2 0.1 5.6 5 2 2 7 7 4 2 Tetratricopeptide repeat Suf PF05843.14 CCU98145.1 - 8.4e-05 22.7 0.2 8.4e-05 22.7 0.2 3.1 2 1 2 4 4 4 1 Suppressor of forked protein (Suf) TPR_8 PF13181.6 CCU98145.1 - 0.0051 16.9 0.0 23 5.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCU98145.1 - 0.034 14.8 3.8 8 7.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCU98145.1 - 0.039 14.6 1.3 0.78 10.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CCU98145.1 - 0.04 14.0 3.4 15 6.0 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCU98145.1 - 0.06 13.6 3.4 0.56 10.5 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RNA_pol_Rbc25 PF08292.12 CCU98145.1 - 0.086 13.1 0.1 42 4.4 0.0 4.3 3 1 0 4 4 4 0 RNA polymerase III subunit Rpc25 RPN7 PF10602.9 CCU98145.1 - 0.15 11.8 0.0 0.39 10.4 0.0 1.7 1 1 0 1 1 1 0 26S proteasome subunit RPN7 RNase_II_C_S1 PF18614.1 CCU98145.1 - 2.1 8.4 25.7 1.2 9.1 0.0 8.2 7 1 0 7 7 7 0 RNase II-type exonuclease C-terminal S1 domain TPR_4 PF07721.14 CCU98145.1 - 4.1 8.3 7.1 28 5.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANTH PF07651.16 CCU98146.1 - 8.3e-70 234.9 1.6 1.1e-69 234.5 0.1 2.0 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 CCU98146.1 - 9.2e-53 178.6 9.6 9.2e-53 178.6 9.6 5.2 4 1 0 5 5 5 2 I/LWEQ domain ENTH PF01417.20 CCU98146.1 - 0.0089 16.1 0.0 0.037 14.1 0.0 2.1 1 0 0 1 1 1 1 ENTH domain PC-Esterase PF13839.6 CCU98146.1 - 0.022 14.5 0.0 0.41 10.3 0.0 2.6 2 0 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Arrestin_N PF00339.29 CCU98147.1 - 3.7e-05 23.8 0.0 8.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain CxC1 PF18802.1 CCU98147.1 - 0.14 12.4 0.1 11 6.3 0.0 2.3 2 0 0 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases DSHCT PF08148.12 CCU98148.1 - 1.7e-50 170.9 0.7 1.7e-50 170.9 0.7 2.2 3 0 0 3 3 3 1 DSHCT (NUC185) domain Ski2_N PF17911.1 CCU98148.1 - 7.5e-31 106.7 0.0 1.9e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 CCU98148.1 - 4e-23 82.7 0.0 7.1e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 CCU98148.1 - 5.9e-08 32.7 0.1 1.1e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU98148.1 - 2.3e-05 24.7 0.0 7.5e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain RcbX PF02341.15 CCU98148.1 - 0.14 12.4 0.9 0.31 11.3 0.9 1.5 1 0 0 1 1 1 0 RbcX protein PGP_phosphatase PF09419.10 CCU98149.1 - 3.2e-41 140.7 0.0 5.3e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 CCU98149.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like P34-Arc PF04045.14 CCU98150.1 - 1.9e-103 345.4 0.0 2.3e-103 345.1 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Methyltransf_16 PF10294.9 CCU98151.1 - 3.6e-11 43.1 0.0 4.3e-10 39.6 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 CCU98151.1 - 0.051 14.3 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_5 PF00266.19 CCU98152.1 - 2.7e-30 105.6 0.0 3.6e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CCU98152.1 - 0.0041 15.7 0.0 0.0069 15.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.19 CCU98152.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Pro_isomerase PF00160.21 CCU98153.1 - 6e-48 163.1 0.1 9e-48 162.5 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CCU98153.1 - 2e-05 24.3 4.6 0.0061 16.6 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CCU98153.1 - 0.0053 16.5 0.8 0.15 11.9 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCU98153.1 - 0.48 10.1 1.7 1.4 8.7 0.3 2.2 2 0 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 CCU98153.1 - 2 9.2 5.4 7.5 7.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RhoGAP PF00620.27 CCU98154.1 - 1.2e-38 132.4 0.1 3.2e-38 131.0 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain Pro_isomerase PF00160.21 CCU98155.1 - 3e-50 170.6 0.0 3.6e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Aldedh PF00171.22 CCU98156.1 - 2e-160 534.3 0.0 2.3e-160 534.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Thx PF17070.5 CCU98156.1 - 0.12 12.5 1.2 0.29 11.3 1.2 1.5 1 0 0 1 1 1 0 30S ribosomal protein Thx LuxC PF05893.14 CCU98156.1 - 0.17 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Ribosomal_L22 PF00237.19 CCU98157.1 - 2.2e-24 85.7 0.2 3.3e-24 85.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e AAA_18 PF13238.6 CCU98158.1 - 8.8e-13 48.9 0.2 6e-12 46.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain HTH_28 PF13518.6 CCU98158.1 - 0.061 13.5 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain GDI PF00996.18 CCU98159.1 - 7.5e-211 700.2 0.0 8.6e-211 700.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CCU98159.1 - 0.0059 16.8 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain peroxidase PF00141.23 CCU98161.1 - 8.2e-50 169.6 0.0 1.4e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Coatomer_E PF04733.14 CCU98162.1 - 9.4e-31 107.3 3.2 1.1e-30 107.1 3.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 CCU98162.1 - 0.11 12.7 3.6 2.2 8.6 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCU98162.1 - 0.15 12.3 1.9 0.68 10.2 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Mito_carr PF00153.27 CCU98163.1 - 2.2e-55 184.6 0.5 1.5e-18 66.5 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein GST_C_6 PF17171.4 CCU98163.1 - 3.4e-06 26.8 0.0 7.9e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCU98163.1 - 0.00026 21.0 1.7 0.00064 19.7 0.3 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CCU98163.1 - 0.014 16.1 0.0 0.032 15.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF2835 PF11197.8 CCU98163.1 - 0.045 13.6 1.9 0.062 13.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2835) Hydantoinase_A PF01968.18 CCU98165.1 - 1.1e-91 307.2 0.7 1.6e-91 306.6 0.7 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CCU98165.1 - 2.1e-54 183.9 0.1 4.8e-52 176.2 0.0 3.0 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region dCMP_cyt_deam_1 PF00383.23 CCU98166.1 - 1.4e-11 44.2 0.4 1.8e-11 43.8 0.4 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CCU98166.1 - 2.5e-09 37.4 1.8 1.1e-06 28.8 0.2 2.3 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CCU98166.1 - 0.0043 16.7 5.5 0.031 13.9 0.2 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases XOO_2897-deam PF14440.6 CCU98166.1 - 0.041 14.0 0.1 0.063 13.4 0.1 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Carb_kinase PF01256.17 CCU98168.1 - 9.9e-50 169.3 0.0 1.8e-49 168.4 0.0 1.4 1 1 0 1 1 1 1 Carbohydrate kinase AMP-binding PF00501.28 CCU98169.1 - 1.4e-84 284.1 0.0 1.8e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCU98169.1 - 6.1e-12 46.3 0.0 2.4e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 CCU98169.1 - 0.00017 20.6 0.0 0.0059 15.5 0.0 2.3 2 0 0 2 2 2 2 GH3 auxin-responsive promoter UBA_3 PF09288.10 CCU98170.1 - 1.7e-14 53.4 0.0 2.4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain DUF1421 PF07223.11 CCU98170.1 - 1.5e-05 24.7 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain (DUF1421) UBA_6 PF18039.1 CCU98170.1 - 0.00022 21.1 0.0 0.00039 20.3 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UQ_con PF00179.26 CCU98170.1 - 0.00032 20.4 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PAF-AH_p_II PF03403.13 CCU98171.1 - 6e-45 153.4 0.1 2.8e-23 82.1 0.0 3.6 3 1 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 CCU98171.1 - 1.5e-07 30.6 0.0 1.3e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 CCU98171.1 - 3.4e-06 26.5 0.0 0.0072 15.6 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 CCU98171.1 - 4.7e-05 22.5 0.0 0.00051 19.2 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_1 PF00561.20 CCU98171.1 - 0.0075 15.9 0.0 1.9 8.1 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCU98171.1 - 0.0076 16.9 0.2 0.057 14.0 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CCU98171.1 - 0.025 14.1 0.0 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family IGR PF09597.10 CCU98172.1 - 2.8e-12 46.6 0.4 4.6e-12 45.8 0.4 1.5 1 1 0 1 1 1 1 IGR protein motif Glyco_trans_2_3 PF13632.6 CCU98172.1 - 0.27 11.1 0.3 0.45 10.4 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase family group 2 V-SNARE PF05008.15 CCU98173.1 - 1.1e-17 64.1 1.3 1.1e-17 64.1 1.3 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 CCU98173.1 - 5.8e-14 52.1 3.1 1.5e-13 50.8 3.1 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 CCU98173.1 - 0.02 12.9 0.2 0.087 10.8 0.1 1.7 2 0 0 2 2 2 0 Prominin CENP-F_leu_zip PF10473.9 CCU98173.1 - 0.057 13.4 0.9 0.11 12.5 0.2 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF883 PF05957.13 CCU98173.1 - 0.75 10.4 10.1 3.6 8.2 2.3 3.2 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Lectin_N PF03954.14 CCU98173.1 - 0.77 9.5 3.3 0.69 9.7 0.2 2.5 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain BCDHK_Adom3 PF10436.9 CCU98174.1 - 1.5e-41 141.9 0.0 2.1e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CCU98174.1 - 8.1e-08 32.8 0.0 2.1e-07 31.4 0.0 1.8 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CCU98174.1 - 0.00052 19.9 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SHR3_chaperone PF08229.11 CCU98175.1 - 4.9e-32 110.4 0.1 6e-32 110.1 0.1 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 SecG PF03840.14 CCU98175.1 - 0.1 12.7 0.5 0.1 12.7 0.5 2.7 4 0 0 4 4 4 0 Preprotein translocase SecG subunit ABC_membrane PF00664.23 CCU98177.1 - 7.3e-37 127.5 10.5 1.1e-36 126.9 10.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CCU98177.1 - 3.2e-35 121.6 0.0 6.4e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CCU98177.1 - 2.5e-05 23.8 0.0 0.00041 19.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCU98177.1 - 0.0041 16.8 0.1 0.0089 15.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CCU98177.1 - 0.0052 17.2 0.1 0.0052 17.2 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCU98177.1 - 0.01 16.1 0.2 0.052 13.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CCU98177.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ABC_membrane_3 PF13748.6 CCU98177.1 - 0.013 14.7 1.2 0.025 13.8 0.1 2.0 2 0 0 2 2 2 0 ABC transporter transmembrane region G-alpha PF00503.20 CCU98177.1 - 0.029 13.5 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA PF00004.29 CCU98177.1 - 0.035 14.5 0.0 0.35 11.3 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 CCU98177.1 - 0.037 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 CCU98177.1 - 0.066 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_10 PF12846.7 CCU98177.1 - 0.1 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain HpcH_HpaI PF03328.14 CCU98178.1 - 4.1e-34 117.7 2.3 5.1e-34 117.3 2.3 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 CCU98178.1 - 3.7e-13 49.4 0.5 1.9e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold FAR1 PF03101.15 CCU98179.1 - 0.0012 19.5 0.1 0.0026 18.4 0.1 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF4771 PF15995.5 CCU98179.1 - 0.13 12.5 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) Pribosyltran PF00156.27 CCU98180.1 - 2.1e-12 46.8 0.0 2.7e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCU98180.1 - 0.0022 17.5 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CGI-121 PF08617.10 CCU98181.1 - 6.8e-45 153.1 0.0 7.9e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 GLTSCR1 PF15249.6 CCU98182.1 - 2e-15 57.1 4.5 7.3e-15 55.3 4.5 1.9 1 1 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein OmpH PF03938.14 CCU98182.1 - 0.94 9.8 3.1 1.7 9.0 3.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_L1 PF00687.21 CCU98183.1 - 3.5e-18 66.1 0.0 9.4e-18 64.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Toprim_3 PF13362.6 CCU98183.1 - 0.1 13.0 0.2 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 Toprim domain Haspin_kinase PF12330.8 CCU98184.1 - 4.8e-55 187.0 0.0 6.1e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase PF00069.25 CCU98184.1 - 0.085 12.2 0.0 0.5 9.7 0.0 2.0 1 1 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98184.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Sugar_tr PF00083.24 CCU98186.1 - 3.6e-210 698.6 45.6 2.8e-105 352.8 23.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CCU98186.1 - 7e-45 153.5 86.4 1.4e-22 80.1 29.7 4.1 2 2 2 4 4 4 3 Major Facilitator Superfamily GARS_A PF01071.19 CCU98187.1 - 1.8e-71 240.0 0.0 2.5e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 CCU98187.1 - 1.1e-32 113.3 0.0 2.2e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 CCU98187.1 - 7.9e-32 109.9 0.1 2.1e-31 108.6 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 CCU98187.1 - 1.8e-27 95.4 1.0 1.1e-26 92.9 0.5 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 CCU98187.1 - 3e-14 53.4 2.2 1.9e-13 50.9 0.9 2.7 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 CCU98187.1 - 0.0061 16.6 0.0 0.017 15.2 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 CCU98187.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain CAF1C_H4-bd PF12265.8 CCU98188.1 - 1.4e-17 63.7 0.1 6.5e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CCU98188.1 - 8.6e-15 54.9 15.1 1.2e-05 26.0 0.2 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Es2 PF09751.9 CCU98190.1 - 8.8e-58 197.1 4.2 8.8e-58 197.1 4.2 3.0 2 1 1 3 3 3 2 Nuclear protein Es2 Rsm22 PF09243.10 CCU98191.1 - 4.7e-36 124.5 0.2 6.7e-25 87.9 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Ima1_N PF09779.9 CCU98192.1 - 9.8e-12 45.9 0.4 1.1e-10 42.5 0.1 2.1 2 0 0 2 2 2 1 Ima1 N-terminal domain Lar_restr_allev PF14354.6 CCU98192.1 - 1.4 9.4 4.6 8 6.9 1.3 2.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar DUF1244 PF06844.11 CCU98192.1 - 2.7 8.2 5.7 0.53 10.5 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1244) Lyase_1 PF00206.20 CCU98193.1 - 2.8e-120 401.4 0.1 4e-120 400.9 0.1 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CCU98193.1 - 1.9e-18 66.6 0.1 4.1e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus G-alpha PF00503.20 CCU98193.1 - 0.25 10.4 0.0 0.46 9.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit RRM_1 PF00076.22 CCU98194.1 - 2.5e-19 68.8 0.0 3e-10 39.8 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCU98194.1 - 0.0022 17.6 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CCU98194.1 - 0.021 14.9 0.0 0.052 13.6 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 Ilar_coat PF01787.16 CCU98194.1 - 0.25 11.1 3.2 0.41 10.4 3.2 1.3 1 0 0 1 1 1 0 Ilarvirus coat protein Pescadillo_N PF06732.11 CCU98195.1 - 8.2e-120 399.4 0.2 1.8e-119 398.3 0.2 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 CCU98195.1 - 3.6e-06 27.3 0.0 2.5e-05 24.6 0.0 2.4 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BUD22 PF09073.10 CCU98196.1 - 9.6e-57 193.2 25.6 6.1e-55 187.3 25.6 2.0 1 1 0 1 1 1 1 BUD22 Pyr_redox_3 PF13738.6 CCU98197.1 - 1.6e-10 40.8 0.0 2.3e-08 33.7 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CCU98197.1 - 7.3e-09 35.3 0.0 1.4e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 CCU98197.1 - 1.9e-08 33.2 0.0 4.5e-08 32.0 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 CCU98197.1 - 1.3e-06 27.8 0.0 0.0017 17.6 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CCU98197.1 - 1.3e-05 25.4 0.0 2.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CCU98197.1 - 0.0018 17.9 0.2 0.077 12.6 0.0 2.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase DUF4060 PF13269.6 CCU98197.1 - 0.027 14.6 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4060) NAD_binding_9 PF13454.6 CCU98197.1 - 0.036 14.0 0.3 17 5.4 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CCU98197.1 - 0.064 12.3 0.1 4.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 CCU98197.1 - 0.088 13.4 0.0 5.3 7.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 CCU98198.1 - 8.1e-30 102.9 0.1 9.2e-30 102.7 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CCU98198.1 - 5.6e-09 36.4 0.2 1.6e-07 31.7 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CCU98198.1 - 6e-06 26.5 0.0 0.00015 22.0 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CCU98198.1 - 6.5e-06 25.7 0.0 6.5e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 CCU98198.1 - 2.4e-05 24.1 0.0 2.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 CCU98198.1 - 8.5e-05 22.5 0.1 0.00016 21.6 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCU98198.1 - 0.00082 19.1 1.1 0.021 14.5 0.3 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 CCU98198.1 - 0.0018 18.4 0.0 0.0025 18.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 CCU98198.1 - 0.021 14.8 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 CCU98198.1 - 0.021 14.5 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DIM1 PF02966.16 CCU98198.1 - 0.021 14.6 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Glutaredoxin PF00462.24 CCU98198.1 - 0.023 14.9 0.2 0.043 14.0 0.2 1.5 1 1 0 1 1 1 0 Glutaredoxin DSBA PF01323.20 CCU98198.1 - 0.055 13.2 0.6 0.084 12.6 0.2 1.5 1 1 1 2 2 2 0 DSBA-like thioredoxin domain MTP18 PF10558.9 CCU98199.1 - 4.3e-54 183.0 4.0 7.9e-52 175.7 4.0 2.2 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Exo_endo_phos PF03372.23 CCU98200.1 - 1.8e-07 30.9 0.7 6.9e-07 29.0 0.7 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ubie_methyltran PF01209.18 CCU98201.1 - 1.6e-70 237.1 0.0 1e-36 126.4 0.0 2.4 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CCU98201.1 - 4.5e-12 46.5 0.0 2.5e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CCU98201.1 - 2.5e-10 40.9 0.0 1.4e-05 25.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CCU98201.1 - 1.1e-09 38.9 0.0 2.7e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCU98201.1 - 1.1e-06 28.5 0.0 5.2e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCU98201.1 - 0.00017 21.5 0.0 0.00029 20.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Suc_Fer-like PF06999.12 CCU98202.1 - 1.7e-24 86.8 0.0 3.4e-24 85.8 0.0 1.5 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Fer2 PF00111.27 CCU98202.1 - 5.5e-08 32.7 1.4 5.5e-08 32.7 1.4 2.5 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain SSB PF00436.25 CCU98203.1 - 7.5e-14 51.6 0.0 9e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Band_7 PF01145.25 CCU98205.1 - 1.2e-24 87.2 4.6 2.4e-24 86.3 4.6 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CCU98205.1 - 0.004 16.3 2.7 0.0051 15.9 2.7 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial AAA_lid_4 PF17864.1 CCU98205.1 - 0.17 11.7 2.9 0.17 11.7 0.2 2.3 2 1 0 2 2 2 0 RuvB AAA lid domain Acetyltransf_3 PF13302.7 CCU98206.1 - 5.6e-16 59.5 0.0 6.8e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCU98206.1 - 7.5e-07 29.0 0.0 2.4e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 CCU98206.1 - 0.00052 20.2 0.0 0.0022 18.2 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 CCU98206.1 - 0.00091 18.9 0.1 0.0024 17.6 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CCU98206.1 - 0.0023 18.1 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCU98206.1 - 0.044 14.2 0.0 0.066 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CCU98206.1 - 0.14 12.1 0.1 1 9.3 0.1 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR_2 PF13233.6 CCU98207.1 - 3.5e-19 69.3 0.0 4.9e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CCU98207.1 - 4.5e-09 36.2 0.0 7.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) SWIB PF02201.18 CCU98208.1 - 1.5e-22 79.2 0.1 6.6e-22 77.2 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 CCU98208.1 - 6.8e-08 32.3 0.9 1.6e-06 28.0 0.9 2.3 1 1 0 1 1 1 1 DEK C terminal domain PRTP PF01366.18 CCU98208.1 - 0.0037 15.4 1.4 0.012 13.7 1.1 1.7 1 1 1 2 2 2 1 Herpesvirus processing and transport protein PP2C_C PF07830.13 CCU98208.1 - 0.048 14.1 0.1 0.14 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain G6B PF15096.6 CCU98208.1 - 0.089 12.6 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 G6B family CBFD_NFYB_HMF PF00808.23 CCU98209.1 - 2.3e-08 34.2 1.7 1.7e-07 31.4 1.7 2.1 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CCU98209.1 - 0.0042 17.4 0.8 0.023 15.0 0.8 1.9 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Orbi_VP4 PF05059.12 CCU98209.1 - 0.13 10.3 0.1 5.7 4.8 0.0 2.0 2 0 0 2 2 2 0 Orbivirus VP4 core protein Translin PF01997.16 CCU98210.1 - 8.6e-42 143.5 0.0 1.1e-41 143.1 0.0 1.0 1 0 0 1 1 1 1 Translin family DUF1320 PF07030.12 CCU98210.1 - 0.14 12.3 3.2 2 8.6 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1320) DUF2746 PF10874.8 CCU98210.1 - 0.19 12.2 0.7 1 9.9 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2746) Abhydrolase_1 PF00561.20 CCU98211.1 - 2.5e-21 76.5 0.0 9.5e-19 68.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCU98211.1 - 1.9e-17 64.6 10.2 1.9e-17 64.6 10.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCU98211.1 - 3.7e-15 55.8 0.0 2.2e-14 53.3 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 CCU98211.1 - 7.6e-06 25.7 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 CCU98211.1 - 4.1e-05 23.5 0.0 0.00048 20.0 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CCU98211.1 - 5.5e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 CCU98211.1 - 0.00052 19.6 0.0 0.00079 19.1 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ndr PF03096.14 CCU98211.1 - 0.00093 18.0 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family UPF0227 PF05728.12 CCU98211.1 - 0.0022 17.9 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.16 CCU98211.1 - 0.0045 16.8 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF915 PF06028.11 CCU98211.1 - 0.0098 15.3 0.0 0.18 11.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 CCU98211.1 - 0.011 15.4 0.3 0.25 11.0 0.3 2.1 1 1 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 CCU98211.1 - 0.012 14.6 0.0 0.041 12.8 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 CCU98211.1 - 0.067 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.11 CCU98211.1 - 0.098 11.7 0.0 0.26 10.3 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase Peptidase_S9 PF00326.21 CCU98211.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Thioesterase PF00975.20 CCU98211.1 - 0.15 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 CCU98211.1 - 0.17 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family NPL4 PF05021.15 CCU98212.1 - 2.5e-107 358.8 0.0 3.1e-107 358.5 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CCU98212.1 - 8.8e-66 220.5 0.0 1.4e-65 219.9 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 CCU98212.1 - 0.035 14.6 0.0 0.062 13.8 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF3530 PF12048.8 CCU98212.1 - 0.56 9.6 3.3 0.44 9.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) DZR PF12773.7 CCU98212.1 - 2.4 8.3 9.2 0.094 12.8 0.5 2.9 3 0 0 3 3 3 0 Double zinc ribbon zf-RanBP PF00641.18 CCU98212.1 - 7.8 5.9 7.2 0.19 11.1 0.5 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Spc7 PF08317.11 CCU98214.1 - 0.018 13.9 4.0 0.034 13.0 4.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein RasGAP_C PF03836.15 CCU98214.1 - 0.041 14.0 0.8 0.084 13.0 0.8 1.4 1 0 0 1 1 1 0 RasGAP C-terminus Transcrip_act PF04949.13 CCU98214.1 - 0.058 13.3 1.1 0.11 12.3 1.1 1.4 1 0 0 1 1 1 0 Transcriptional activator DUF3584 PF12128.8 CCU98214.1 - 0.072 10.6 12.7 0.11 10.0 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) OmpH PF03938.14 CCU98214.1 - 0.18 12.1 7.9 0.54 10.6 7.9 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-F_leu_zip PF10473.9 CCU98214.1 - 0.23 11.5 8.3 0.11 12.6 5.5 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 CCU98214.1 - 0.69 8.5 3.7 1.1 7.8 3.7 1.2 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 CCU98214.1 - 0.8 8.7 10.7 0.69 8.9 8.9 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 CCU98214.1 - 5.7 7.4 11.3 5.5 7.4 7.9 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Ras PF00071.22 CCU98215.1 - 1.2e-41 142.0 0.0 1.4e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCU98215.1 - 6.5e-13 49.0 0.0 8.9e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU98215.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ribosomal_L29 PF00831.23 CCU98216.1 - 5.2e-05 23.1 4.1 0.00071 19.5 0.3 2.3 2 0 0 2 2 2 2 Ribosomal L29 protein SecE PF00584.20 CCU98217.1 - 4.8e-16 58.4 0.0 6.5e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Img2 PF05046.14 CCU98218.1 - 1.2e-19 70.3 0.0 1.6e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) COX5B PF01215.19 CCU98219.1 - 6.8e-39 132.5 0.0 8.3e-39 132.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 CCU98219.1 - 0.1 12.7 1.0 0.15 12.1 1.0 1.3 1 0 0 1 1 1 0 Zinc-finger domain SH3_1 PF00018.28 CCU98220.1 - 2.6e-11 42.9 0.1 4.4e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCU98220.1 - 6.7e-10 38.7 0.0 1.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCU98220.1 - 5.1e-09 35.7 0.0 1.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 CCU98220.1 - 0.0061 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain ATG16 PF08614.11 CCU98221.1 - 0.12 12.5 8.2 1.2 9.3 7.7 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Macoilin PF09726.9 CCU98221.1 - 0.22 10.1 0.4 0.3 9.6 0.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF3563 PF12086.8 CCU98221.1 - 0.51 10.1 6.3 4.7 7.0 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3563) DUF4407 PF14362.6 CCU98221.1 - 0.52 9.6 6.5 0.24 10.7 4.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UTP25 PF06862.12 CCU98222.1 - 2.9e-163 544.0 0.0 3.4e-163 543.8 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 MMR_HSR1 PF01926.23 CCU98223.1 - 4.4e-15 55.8 0.0 3.3e-14 52.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCU98223.1 - 2.5e-07 30.8 0.1 0.00088 19.2 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CCU98223.1 - 3.4e-05 23.4 0.0 0.00012 21.6 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 CCU98223.1 - 0.012 14.9 0.0 0.028 13.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 CCU98223.1 - 0.029 14.4 0.5 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 Dynamin family AAA_16 PF13191.6 CCU98223.1 - 0.8 10.1 5.1 10 6.5 0.0 3.5 2 1 1 3 3 3 0 AAA ATPase domain Peptidase_S9_N PF02897.15 CCU98224.1 - 1.7e-81 274.2 0.3 2.4e-81 273.7 0.3 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CCU98224.1 - 6.7e-45 153.2 1.1 1.4e-44 152.2 1.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CCU98224.1 - 0.0017 18.2 0.1 0.0037 17.2 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pre-PUA PF17832.1 CCU98225.1 - 2.3e-21 76.2 0.0 3.2e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CCU98225.1 - 3.7e-15 55.6 0.0 5.2e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 PUA domain Peptidase_C12 PF01088.21 CCU98227.1 - 3.1e-54 183.9 0.0 3.7e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 TetR_C_24 PF17932.1 CCU98227.1 - 0.0059 16.9 0.2 0.037 14.3 0.0 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain UDG PF03167.19 CCU98228.1 - 8.5e-10 38.8 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Pro_CA PF00484.19 CCU98229.1 - 2.1e-39 135.3 0.0 3.2e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase DUF711 PF05167.12 CCU98229.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) ADH_zinc_N PF00107.26 CCU98230.1 - 6.5e-20 71.4 0.0 1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCU98230.1 - 9e-15 54.5 6.9 2.8e-14 52.9 5.0 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 CCU98230.1 - 0.0004 19.7 0.0 0.00083 18.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CCU98230.1 - 0.00053 19.4 0.5 0.0033 16.8 0.4 2.0 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.19 CCU98230.1 - 0.018 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ApbA PF02558.16 CCU98230.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AIRC PF00731.20 CCU98230.1 - 0.077 12.6 0.2 2.3 7.8 0.0 2.2 1 1 1 2 2 2 0 AIR carboxylase Polyketide_cyc PF03364.20 CCU98231.1 - 1e-23 84.0 0.0 1.3e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Prenyltransf PF01255.19 CCU98232.1 - 1.4e-56 191.6 0.0 2.7e-56 190.6 0.0 1.5 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CDC45 PF02724.14 CCU98232.1 - 0.046 12.0 23.4 0.07 11.4 23.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CCU98232.1 - 0.26 10.0 17.0 0.38 9.5 17.0 1.2 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 CCU98232.1 - 0.27 10.3 15.2 0.37 9.8 15.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC27 PF09507.10 CCU98232.1 - 0.28 10.5 33.1 0.44 9.9 33.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Zip PF02535.22 CCU98232.1 - 1 8.5 9.3 1.7 7.8 9.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SRP-alpha_N PF04086.13 CCU98232.1 - 1.8 8.4 28.1 2.9 7.7 28.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SLC12 PF03522.15 CCU98232.1 - 1.9 7.4 18.3 2.8 6.9 18.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 CCU98232.1 - 2 7.2 11.4 2.7 6.7 11.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Membralin PF09746.9 CCU98232.1 - 2.3 7.2 11.3 3.6 6.5 11.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein Borrelia_P83 PF05262.11 CCU98232.1 - 3.7 5.9 26.1 5.1 5.5 26.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur_chan_memb PF02932.16 CCU98232.1 - 3.8 7.5 10.7 5.8 6.9 10.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_11 PF13086.6 CCU98232.1 - 7.4 6.3 19.4 3.2 7.4 17.0 1.7 2 0 0 2 2 2 0 AAA domain DUF3844 PF12955.7 CCU98233.1 - 5.9e-24 84.2 0.3 9.3e-24 83.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) His_Phos_2 PF00328.22 CCU98233.1 - 1e-12 48.1 0.0 9.5e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) PE PF00934.20 CCU98233.1 - 0.68 10.3 6.3 2.1 8.7 6.3 1.9 1 0 0 1 1 1 0 PE family Mito_carr PF00153.27 CCU98234.1 - 5.7e-29 99.9 0.6 6e-14 51.7 0.0 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein LapA_dom PF06305.11 CCU98234.1 - 0.086 12.7 0.3 12 5.8 0.0 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF2637 PF10935.8 CCU98234.1 - 0.23 11.4 4.7 2.8 7.8 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2637) Iso_dh PF00180.20 CCU98235.1 - 4.2e-66 223.5 0.0 5.1e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_88 PF07470.13 CCU98236.1 - 5.2e-18 65.2 0.0 9.4e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 AMP-binding PF00501.28 CCU98236.1 - 0.00074 18.2 0.1 0.0013 17.4 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Rit1_C PF17184.4 CCU98237.1 - 4.8e-71 239.4 0.0 6.1e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 CCU98237.1 - 1.3e-07 31.9 0.0 2.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain US22 PF02393.16 CCU98237.1 - 0.022 15.0 0.0 0.13 12.5 0.0 2.3 1 1 0 1 1 1 0 US22 like Pro-kuma_activ PF09286.11 CCU98238.1 - 2e-25 89.7 0.0 3.5e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CCU98238.1 - 9e-08 31.7 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Rotamase PF00639.21 CCU98239.1 - 1.2e-20 74.3 0.1 3.7e-19 69.5 0.1 2.1 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CCU98239.1 - 3.8e-18 66.1 0.0 8.8e-18 64.9 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CCU98239.1 - 1e-05 26.4 0.0 1.4e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CCU98239.1 - 1.7e-05 24.8 0.4 5.7e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 WW domain X8 PF07983.13 CCU98239.1 - 0.048 14.3 0.0 0.086 13.5 0.0 1.3 1 0 0 1 1 1 0 X8 domain CMAS PF02353.20 CCU98241.1 - 1.6e-64 217.8 0.0 2e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CCU98241.1 - 5.2e-14 52.7 0.0 1.7e-13 51.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCU98241.1 - 2.7e-13 50.1 0.0 5.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCU98241.1 - 3.3e-12 46.9 0.0 2.1e-11 44.3 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCU98241.1 - 9.1e-08 32.0 0.0 2.2e-07 30.8 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCU98241.1 - 8.9e-07 29.6 0.0 2.4e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCU98241.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CCU98241.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 CCU98241.1 - 0.0026 17.3 0.0 0.026 14.0 0.0 2.1 2 0 0 2 2 2 1 Histone methylation protein DOT1 PrmA PF06325.13 CCU98241.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 CCU98241.1 - 0.015 15.0 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein MetW PF07021.12 CCU98241.1 - 0.04 13.5 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CCU98241.1 - 0.11 12.5 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain YtxH PF12732.7 CCU98241.1 - 0.17 12.4 0.3 0.38 11.3 0.3 1.5 1 0 0 1 1 1 0 YtxH-like protein Gtr1_RagA PF04670.12 CCU98242.1 - 7.8e-82 274.1 0.0 1.1e-81 273.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 CCU98242.1 - 0.00011 22.4 0.0 0.00024 21.3 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU98242.1 - 0.00011 21.7 0.0 0.00034 20.1 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 CCU98242.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.5 1 1 0 1 1 1 1 Ras family G-alpha PF00503.20 CCU98242.1 - 0.033 13.4 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DUF1640 PF07798.11 CCU98243.1 - 3.5e-59 199.8 5.5 3.9e-59 199.6 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) LppC PF04348.13 CCU98243.1 - 0.012 14.4 1.5 0.012 14.4 1.5 1.1 1 0 0 1 1 1 0 LppC putative lipoprotein HALZ PF02183.18 CCU98243.1 - 0.031 14.5 3.0 0.19 12.0 3.0 2.1 1 1 0 1 1 1 0 Homeobox associated leucine zipper Putative_PNPOx PF01243.20 CCU98244.1 - 6.9e-17 61.4 0.1 2.6e-16 59.6 0.1 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 CCU98244.1 - 3e-13 49.6 2.7 6.1e-13 48.6 2.7 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 CCU98244.1 - 0.026 15.1 0.0 0.045 14.4 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase HlyIII PF03006.20 CCU98245.1 - 2.5e-23 83.0 7.9 3.5e-23 82.5 7.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related UPF0060 PF02694.15 CCU98245.1 - 0.011 15.9 3.2 0.051 13.8 0.5 2.3 1 1 1 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Rep_fac_C PF08542.11 CCU98246.1 - 5.4e-30 103.7 0.0 3.5e-29 101.1 0.0 2.3 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CCU98246.1 - 4.1e-10 39.7 0.0 6.1e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CCU98246.1 - 0.00025 21.5 0.0 0.00048 20.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 CCU98246.1 - 0.036 14.4 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain PPR_1 PF12854.7 CCU98246.1 - 0.14 11.9 0.1 0.37 10.5 0.1 1.7 1 0 0 1 1 1 0 PPR repeat Kelch_4 PF13418.6 CCU98247.1 - 1.8e-32 111.1 9.1 1.9e-05 24.6 0.2 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CCU98247.1 - 4.4e-32 109.5 5.4 1.4e-06 28.1 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CCU98247.1 - 3.8e-29 100.4 10.6 2e-06 28.0 0.1 8.1 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 CCU98247.1 - 4.4e-26 90.2 5.9 1.1e-08 35.1 0.6 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 CCU98247.1 - 1.4e-22 78.9 7.0 4.1e-07 29.5 0.7 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CCU98247.1 - 7.2e-22 76.5 7.6 0.00057 19.8 0.4 6.5 6 0 0 6 6 6 4 Kelch motif TRCF PF03461.15 CCU98247.1 - 0.051 14.0 0.8 7.3 7.0 0.4 3.0 2 0 0 2 2 2 0 TRCF domain GldM_N PF12081.8 CCU98247.1 - 1.2 9.1 15.5 0.33 11.0 7.2 2.7 2 0 0 2 2 2 0 GldM N-terminal domain CN_hydrolase PF00795.22 CCU98249.1 - 6.2e-29 101.1 0.0 1e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 CCU98249.1 - 1.3e-25 89.9 0.0 1.1e-24 86.9 0.0 2.0 1 1 0 1 1 1 1 NAD synthase Methyltransf_25 PF13649.6 CCU98249.1 - 0.00034 21.2 0.2 0.0027 18.4 0.2 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCU98249.1 - 0.00092 19.0 0.0 0.0031 17.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCU98249.1 - 0.0011 18.8 0.0 0.005 16.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Rhodanese PF00581.20 CCU98249.1 - 0.0079 16.7 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_11 PF08241.12 CCU98249.1 - 0.018 15.6 0.7 0.11 13.1 0.4 2.6 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 CCU98249.1 - 0.045 14.5 0.0 0.12 13.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF4470 PF14737.6 CCU98249.1 - 0.092 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) Methyltransf_33 PF10017.9 CCU98249.1 - 0.24 10.5 0.0 0.42 9.7 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent adh_short PF00106.25 CCU98250.1 - 8.7e-39 133.0 0.0 1.1e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCU98250.1 - 5.2e-23 81.8 0.0 6.7e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCU98250.1 - 2.4e-07 30.8 0.0 3.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CCU98250.1 - 0.0036 16.5 0.0 0.0046 16.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CCU98250.1 - 0.015 15.2 0.1 0.022 14.7 0.1 1.4 1 1 0 1 1 1 0 NAD(P)H-binding LytR_C PF13399.6 CCU98250.1 - 0.14 13.1 0.1 0.33 12.0 0.1 1.6 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator SPOC PF07744.13 CCU98251.1 - 0.02 14.8 0.0 0.058 13.3 0.0 1.8 1 0 0 1 1 1 0 SPOC domain Usp PF00582.26 CCU98252.1 - 4.4e-16 59.7 0.0 5.9e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Glyco_transf_20 PF00982.21 CCU98253.1 - 1e-178 594.9 0.0 8.1e-134 446.9 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Arginosuc_synth PF00764.19 CCU98254.1 - 2.2e-152 507.8 0.0 2.5e-152 507.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase TTL PF03133.15 CCU98256.1 - 6.2e-18 65.0 0.1 7.9e-18 64.6 0.1 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family zf-C2H2 PF00096.26 CCU98257.1 - 1.3e-30 104.1 84.8 6.9e-05 23.1 5.2 10.3 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCU98257.1 - 2.8e-24 83.7 77.1 0.0014 19.2 2.4 10.4 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCU98257.1 - 4.3e-14 52.2 62.0 0.00014 22.1 0.2 10.3 10 1 0 10 10 10 5 Zinc-finger double domain zf-C2H2_8 PF15909.5 CCU98257.1 - 0.00011 22.4 26.8 0.0014 18.9 5.2 3.8 3 1 0 3 3 3 3 C2H2-type zinc ribbon FOXP-CC PF16159.5 CCU98257.1 - 0.062 13.9 0.2 0.062 13.9 0.2 8.5 5 2 5 10 10 10 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CCU98257.1 - 0.13 12.6 33.4 0.15 12.4 0.1 8.7 9 1 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCU98257.1 - 0.25 11.4 0.0 0.25 11.4 0.0 9.2 10 1 0 10 10 10 0 C2H2-type zinc finger FYDLN_acid PF09538.10 CCU98257.1 - 0.49 11.1 2.1 50 4.6 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zf_ZIC PF18366.1 CCU98257.1 - 0.65 10.1 0.0 0.65 10.1 0.0 5.1 7 1 1 8 8 8 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 CCU98257.1 - 7.3 6.7 33.6 0.75 9.9 5.0 5.2 4 1 1 6 6 6 0 Aberrant zinc-finger zf-met PF12874.7 CCU98257.1 - 9.2 6.8 33.9 26 5.4 0.2 8.9 10 0 0 10 10 10 0 Zinc-finger of C2H2 type RRM_1 PF00076.22 CCU98258.1 - 1.4e-31 108.1 0.6 2.4e-18 65.7 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CCU98258.1 - 3.3e-08 34.5 1.3 0.00028 21.9 0.1 2.6 1 1 1 2 2 2 2 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 CCU98258.1 - 0.00032 20.7 0.1 0.21 11.7 0.1 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 CCU98258.1 - 0.00059 19.8 0.1 0.056 13.5 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CCU98258.1 - 0.0021 17.7 0.0 0.14 11.8 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCU98258.1 - 0.0047 16.7 0.0 0.13 12.2 0.0 2.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF4651 PF15513.6 CCU98258.1 - 0.03 14.1 0.0 0.94 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) Glycos_transf_1 PF00534.20 CCU98260.1 - 6.6e-34 116.9 0.0 3e-33 114.8 0.0 2.0 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCU98260.1 - 2.6e-25 89.4 0.0 1e-24 87.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCU98260.1 - 5.8e-20 72.0 0.0 1.2e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CCU98260.1 - 4.8e-09 36.9 0.0 1.1e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CCU98260.1 - 0.028 14.8 0.3 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 BING4CT PF08149.11 CCU98261.1 - 1.4e-37 127.3 0.0 5.5e-36 122.2 0.0 3.1 3 0 0 3 3 3 1 BING4CT (NUC141) domain Coatomer_WDAD PF04053.14 CCU98261.1 - 5e-06 25.8 0.0 7.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CCU98261.1 - 0.00012 22.8 0.0 0.0089 16.9 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat PRK PF00485.18 CCU98262.1 - 3.7e-49 167.2 0.0 4.9e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 CCU98262.1 - 1.3e-41 142.4 0.0 6.6e-39 133.5 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.6 CCU98262.1 - 7.8e-06 26.5 0.0 4.2e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 CCU98262.1 - 0.00049 20.0 0.0 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 CCU98262.1 - 0.033 14.4 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CCU98262.1 - 0.046 13.0 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 CCU98262.1 - 0.18 12.3 0.2 0.76 10.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain CoaE PF01121.20 CCU98262.1 - 0.61 9.7 1.7 2.3 7.9 1.7 1.9 1 1 0 1 1 1 0 Dephospho-CoA kinase Molybdopterin PF00384.22 CCU98263.1 - 2.9e-68 230.8 0.0 4e-66 223.8 0.0 2.8 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 CCU98263.1 - 8.3e-17 61.6 0.0 2.4e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2_4 PF13510.6 CCU98263.1 - 1.1e-16 60.6 0.0 3.2e-16 59.2 0.0 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 CCU98263.1 - 3.3e-16 58.5 0.1 3.3e-16 58.5 0.1 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 CCU98263.1 - 4.7e-08 32.9 0.4 4.7e-08 32.9 0.4 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 CCU98263.1 - 0.0013 18.5 0.1 0.054 13.2 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 CCU98263.1 - 0.21 11.5 1.7 8.3 6.4 0.6 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Arf PF00025.21 CCU98264.1 - 7.4e-13 48.3 0.0 1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCU98264.1 - 5.9e-05 23.3 0.1 0.00018 21.7 0.0 2.0 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CCU98264.1 - 0.0012 18.2 0.0 0.0016 17.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RRS1 PF04939.12 CCU98266.1 - 1.1e-58 197.7 5.0 1.5e-58 197.2 5.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Ribul_P_3_epim PF00834.19 CCU98268.1 - 6.4e-57 192.2 0.1 8.6e-57 191.7 0.1 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.10 CCU98268.1 - 0.008 16.4 0.1 0.018 15.3 0.1 1.5 1 0 0 1 1 1 1 Predicted Peptidoglycan domain QRPTase_C PF01729.19 CCU98268.1 - 0.073 12.8 0.0 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Peptidase_A22B PF04258.13 CCU98269.1 - 8.5e-76 255.2 6.0 1.1e-75 254.8 6.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 CCU98269.1 - 2.5e-05 23.9 7.5 6.4e-05 22.6 7.5 1.7 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 CCU98269.1 - 0.11 11.2 9.6 0.45 9.2 1.0 2.5 2 0 0 2 2 2 0 Presenilin MIF4G PF02854.19 CCU98270.1 - 1.4e-17 64.1 0.0 6.4e-15 55.4 0.0 2.6 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 CCU98270.1 - 1.9e-15 56.8 0.0 6.8e-15 55.0 0.0 2.1 1 0 0 1 1 1 1 MA3 domain DUF572 PF04502.13 CCU98270.1 - 7.7 6.0 10.6 5.8 6.4 8.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) DEAD PF00270.29 CCU98271.1 - 4.8e-40 137.2 0.0 8.1e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU98271.1 - 4.1e-29 101.2 0.0 1.3e-28 99.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU98271.1 - 1.6e-07 31.5 0.0 2.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCU98271.1 - 0.0015 18.8 0.1 0.0037 17.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 CCU98271.1 - 0.003 16.4 0.0 0.36 9.6 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 CCU98271.1 - 0.0065 16.8 0.0 0.011 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 CCU98271.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 CCU98271.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 CCU98271.1 - 0.15 12.1 0.1 0.28 11.1 0.1 1.6 1 1 0 1 1 1 0 Flavivirus DEAD domain Spc7 PF08317.11 CCU98272.1 - 1.5e-48 165.3 3.6 2e-48 164.9 3.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 CCU98272.1 - 0.0003 20.8 0.1 0.00061 19.8 0.1 1.6 1 0 0 1 1 1 1 Spc7_C2 MAD PF05557.13 CCU98272.1 - 0.38 9.0 13.2 0.12 10.7 10.3 1.6 2 0 0 2 2 2 0 Mitotic checkpoint protein KxDL PF10241.9 CCU98272.1 - 0.68 10.3 4.5 6.2 7.2 1.8 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Atg14 PF10186.9 CCU98272.1 - 1.2 8.1 8.2 9.4 5.2 7.1 2.1 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Dus PF01207.17 CCU98274.1 - 2.9e-38 131.7 0.1 4.5e-38 131.1 0.1 1.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TEX13 PF15186.6 CCU98274.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family ubiquitin PF00240.23 CCU98275.1 - 9.3e-05 22.1 0.0 0.00027 20.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CCU98275.1 - 0.0024 17.9 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF4010 PF13194.6 CCU98275.1 - 0.0055 16.4 3.4 0.0067 16.1 1.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4010) VPS28 PF03997.12 CCU98276.1 - 1.8e-46 158.2 0.0 2.2e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.12 CCU98276.1 - 0.14 12.2 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Gas vesicle protein G U1snRNP70_N PF12220.8 CCU98277.1 - 1.1e-20 74.1 3.1 2.7e-20 72.8 3.1 1.7 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CCU98277.1 - 7.3e-17 61.0 0.0 1.2e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.26 CCU98278.1 - 1.3e-47 161.8 0.0 1.7e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCU98278.1 - 6.7e-13 48.1 0.2 1.3e-12 47.2 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ge1_WD40 PF16529.5 CCU98278.1 - 0.16 10.9 0.1 1.2 8.0 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MSC PF09402.10 CCU98279.1 - 4.4e-71 240.1 1.0 5.4e-71 239.8 1.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 CCU98279.1 - 1.2e-10 40.9 0.1 2.5e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 HeH/LEM domain CitG PF01874.16 CCU98279.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 ATP:dephospho-CoA triphosphoribosyl transferase DUF4131 PF13567.6 CCU98279.1 - 0.75 9.4 7.3 0.34 10.6 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Rio2_N PF09202.11 CCU98280.1 - 1.1e-32 112.0 0.1 2.2e-32 111.1 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal RIO1 PF01163.22 CCU98280.1 - 7.3e-28 97.4 5.4 1.3e-14 54.3 2.0 3.2 2 1 0 2 2 2 2 RIO1 family DHHC PF01529.20 CCU98280.1 - 0.00042 20.4 2.9 0.00042 20.4 2.9 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase APH PF01636.23 CCU98280.1 - 0.0012 18.9 0.0 0.015 15.2 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family CobT PF06213.12 CCU98280.1 - 0.0019 17.7 16.9 0.0019 17.7 16.9 1.8 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT XRCC4 PF06632.12 CCU98280.1 - 0.012 14.5 14.1 0.026 13.4 14.1 1.6 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 MarR_2 PF12802.7 CCU98280.1 - 0.048 13.6 0.1 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 MarR family Nop14 PF04147.12 CCU98280.1 - 0.16 10.1 23.7 0.29 9.3 23.7 1.3 1 0 0 1 1 1 0 Nop14-like family Sp38 PF07354.12 CCU98280.1 - 0.2 11.1 0.7 0.39 10.1 0.0 1.7 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) Osteopontin PF00865.18 CCU98280.1 - 0.38 10.2 24.2 0.88 9.0 24.2 1.5 1 0 0 1 1 1 0 Osteopontin CDC45 PF02724.14 CCU98280.1 - 0.87 7.8 19.2 1.6 6.9 19.2 1.3 1 0 0 1 1 1 0 CDC45-like protein SGT1 PF07093.11 CCU98280.1 - 1.6 7.1 7.9 2.2 6.6 7.4 1.5 2 0 0 2 2 2 0 SGT1 protein Vfa1 PF08432.10 CCU98280.1 - 1.6 9.0 8.2 3 8.2 8.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Cellulose_synt PF03552.14 CCU98280.1 - 3.6 5.9 4.4 1.7 7.1 1.9 1.6 1 1 1 2 2 2 0 Cellulose synthase SAPS PF04499.15 CCU98280.1 - 4.8 5.9 6.7 7.2 5.3 6.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.16 CCU98280.1 - 6.3 5.9 13.1 14 4.8 13.1 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.9 CCU98280.1 - 8.8 5.4 30.5 0.05 12.7 21.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Mre11_DNA_bind PF04152.14 CCU98282.1 - 3.5e-39 134.8 0.2 2.6e-38 132.0 0.0 2.0 1 1 1 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CCU98282.1 - 1.9e-11 44.8 0.0 3.3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CCU98282.1 - 0.00018 21.8 0.0 0.0016 18.7 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Rcd1 PF04078.13 CCU98283.1 - 1.5e-123 411.2 3.2 1.8e-123 410.9 3.2 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like cwf21 PF08312.12 CCU98284.1 - 2.6e-15 56.3 8.7 5.7e-15 55.2 8.7 1.6 1 0 0 1 1 1 1 cwf21 domain PMM PF03332.13 CCU98285.1 - 2.1e-99 331.7 0.1 2.5e-99 331.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CCU98285.1 - 3.8e-07 30.1 0.0 3.2e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CCU98285.1 - 0.0021 17.6 0.0 0.29 10.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CCU98285.1 - 0.058 13.7 0.0 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PPR_2 PF13041.6 CCU98288.1 - 1.2e-31 108.6 0.0 4.5e-06 26.8 0.1 8.0 7 1 2 9 9 9 6 PPR repeat family PPR_1 PF12854.7 CCU98288.1 - 1.6e-19 69.3 0.0 0.0049 16.5 0.0 6.8 6 0 0 6 6 6 5 PPR repeat PPR PF01535.20 CCU98288.1 - 3.5e-16 58.2 0.1 0.012 15.8 0.0 7.5 8 0 0 8 8 8 3 PPR repeat PPR_3 PF13812.6 CCU98288.1 - 2.7e-13 49.8 0.3 2.3e-05 24.4 0.0 5.4 4 1 3 7 7 7 3 Pentatricopeptide repeat domain PPR_long PF17177.4 CCU98288.1 - 0.00035 20.0 1.1 0.11 11.8 0.2 2.7 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP DUF2786 PF10979.8 CCU98288.1 - 0.09 12.7 0.3 0.38 10.7 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Acetyltransf_10 PF13673.7 CCU98289.1 - 3.3e-16 59.4 0.1 2.5e-06 27.4 0.0 3.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCU98289.1 - 1.8e-15 57.1 0.0 1.1e-07 32.1 0.0 2.8 2 1 1 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CCU98289.1 - 1.7e-10 41.2 0.0 9.1e-06 25.9 0.0 3.0 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 CCU98289.1 - 4.1e-07 30.7 0.2 5.9e-06 26.9 0.1 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCU98289.1 - 4.7e-07 29.7 0.4 0.011 15.7 0.0 3.2 2 1 0 2 2 2 2 FR47-like protein Acetyltransf_9 PF13527.7 CCU98289.1 - 0.00044 20.3 0.1 2 8.5 0.0 3.5 4 0 0 4 4 4 2 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 CCU98289.1 - 0.027 13.9 0.0 5.9 6.2 0.0 2.2 2 0 0 2 2 2 0 GNAT acetyltransferase 2 CHCH PF06747.13 CCU98290.1 - 5.4e-05 23.2 1.1 7.3e-05 22.8 1.1 1.2 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 CCU98290.1 - 0.01 16.3 1.2 0.014 15.8 1.2 1.2 1 0 0 1 1 1 0 GCK domain CX9C PF16860.5 CCU98290.1 - 0.012 15.6 0.5 0.018 15.0 0.5 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 CCU98290.1 - 0.025 14.6 0.5 0.031 14.3 0.5 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Sec61_beta PF03911.16 CCU98291.1 - 0.0013 18.7 0.0 0.003 17.6 0.0 1.5 2 0 0 2 2 2 1 Sec61beta family Svf1_C PF17187.4 CCU98292.1 - 2e-52 177.3 0.0 3.7e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 CCU98292.1 - 4.4e-40 137.4 0.0 6.4e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Hus1 PF04005.12 CCU98293.1 - 3.8e-24 85.3 0.0 4.6e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein PH PF00169.29 CCU98294.1 - 4.1e-29 101.2 0.0 4.8e-12 46.3 0.0 3.6 4 0 0 4 4 4 3 PH domain PH_11 PF15413.6 CCU98294.1 - 1.4e-14 54.4 8.3 1.9e-05 25.0 0.3 3.7 2 2 0 3 3 3 3 Pleckstrin homology domain PH_8 PF15409.6 CCU98294.1 - 1.9e-07 31.2 1.8 0.00039 20.6 0.0 3.0 4 0 0 4 4 4 2 Pleckstrin homology domain PH_3 PF14593.6 CCU98294.1 - 6.3e-07 29.5 0.2 0.55 10.4 0.0 3.3 3 0 0 3 3 3 3 PH domain Mcp5_PH PF12814.7 CCU98294.1 - 0.00021 21.4 3.2 0.42 10.7 0.0 3.0 3 1 0 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.6 CCU98294.1 - 0.0016 18.8 0.3 24 5.3 0.0 3.8 4 0 0 4 4 4 0 Pleckstrin homology domain PH_2 PF08458.10 CCU98294.1 - 0.0056 17.0 0.0 2.6 8.4 0.0 2.5 2 0 0 2 2 2 2 Plant pleckstrin homology-like region PH_15 PF17339.2 CCU98294.1 - 0.01 15.7 0.3 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 PH domain PH_17 PF18012.1 CCU98294.1 - 0.05 13.3 0.2 4.6 7.0 0.0 2.6 2 0 0 2 2 2 0 PH domain ANAPC5 PF12862.7 CCU98295.1 - 4.1e-12 46.0 0.6 1.3e-11 44.4 0.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 zf-CCCH PF00642.24 CCU98296.1 - 6.8e-12 45.0 39.1 0.0039 17.0 1.7 5.2 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCU98296.1 - 1.3e-06 28.3 34.1 0.0067 16.4 4.6 5.2 5 0 0 5 5 5 3 Zinc finger domain Torus PF16131.5 CCU98296.1 - 1.7e-05 25.4 25.2 0.024 15.3 0.2 5.0 1 1 4 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 CCU98296.1 - 0.0065 16.3 0.2 0.0065 16.3 0.2 4.1 4 0 0 4 4 4 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CCU98296.1 - 1.1 9.5 19.6 2.5 8.3 4.0 3.9 1 1 1 3 3 3 0 Zinc-finger containing family HECT PF00632.25 CCU98297.1 - 4.6e-45 154.4 0.0 5.8e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PRT_C PF08372.10 CCU98298.1 - 0.0087 15.8 0.6 0.03 14.1 0.6 1.9 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 CCU98298.1 - 1.5 8.7 8.7 2.7 8.0 3.4 1.9 1 1 2 3 3 3 0 Reticulon TauE PF01925.19 CCU98298.1 - 3.1 7.4 13.3 3.7 7.1 0.7 2.7 3 0 0 3 3 3 0 Sulfite exporter TauE/SafE NAP PF00956.18 CCU98299.1 - 1.7e-20 73.3 13.3 6.1e-18 65.0 10.0 2.8 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Voldacs PF03517.13 CCU98299.1 - 0.23 11.6 9.1 0.41 10.8 9.1 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling BUD22 PF09073.10 CCU98299.1 - 0.51 9.6 12.8 0.72 9.1 12.8 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 CCU98299.1 - 1.2 7.3 7.6 1.9 6.7 7.6 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 CCU98299.1 - 1.3 8.4 12.2 1.7 8.0 12.2 1.2 1 0 0 1 1 1 0 SDA1 DUF4611 PF15387.6 CCU98299.1 - 4.7 7.5 14.6 3.7 7.8 7.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) C2 PF00168.30 CCU98300.1 - 1.7e-55 185.7 0.0 3.4e-18 65.8 0.0 4.5 4 0 0 4 4 4 4 C2 domain MMM1 PF10296.9 CCU98300.1 - 0.19 10.7 0.0 0.39 9.7 0.0 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Ank_2 PF12796.7 CCU98301.1 - 1.1e-17 64.3 0.0 1.2e-09 38.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCU98301.1 - 3.9e-16 59.2 0.1 2e-08 34.6 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCU98301.1 - 8.8e-14 50.3 0.1 0.0003 21.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 CCU98301.1 - 4.9e-13 48.9 0.8 0.00017 21.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CCU98301.1 - 3.8e-08 33.4 0.7 6.6e-05 23.1 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Arm PF00514.23 CCU98302.1 - 2.1e-95 310.2 13.2 5.1e-13 48.6 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 CCU98302.1 - 9.7e-26 90.0 3.4 1.9e-25 89.1 3.4 1.5 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 CCU98302.1 - 2.3e-21 75.1 1.3 5.8e-21 73.8 1.3 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 CCU98302.1 - 4.6e-19 68.5 3.7 6.4e-06 26.5 0.0 7.0 2 1 6 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 CCU98302.1 - 3.9e-16 59.2 3.5 9.1e-05 22.8 0.0 5.9 2 1 4 7 7 6 6 HEAT repeats HEAT PF02985.22 CCU98302.1 - 1.3e-15 56.2 1.6 0.00031 20.7 0.0 7.2 8 0 0 8 8 8 2 HEAT repeat Arm_2 PF04826.13 CCU98302.1 - 3e-06 26.9 0.0 0.016 14.7 0.0 4.0 2 1 2 4 4 4 1 Armadillo-like RICTOR_V PF14668.6 CCU98302.1 - 1.2e-05 25.4 1.9 0.021 15.1 0.1 3.9 2 2 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 CCU98302.1 - 0.00052 18.7 0.0 0.013 14.1 0.0 2.5 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 CCU98302.1 - 0.0011 19.1 0.0 3.7 7.7 0.0 4.2 3 2 3 6 6 6 2 V-ATPase subunit H Atx10homo_assoc PF09759.9 CCU98302.1 - 0.0077 16.2 0.0 0.19 11.8 0.0 3.0 3 0 0 3 3 2 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 CCU98302.1 - 0.011 16.3 1.1 1.9 9.4 0.0 4.3 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Mo25 PF08569.11 CCU98302.1 - 0.054 12.9 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Mo25-like V-ATPase_H_N PF03224.14 CCU98302.1 - 0.11 11.8 0.0 5.5 6.2 0.0 2.9 1 1 0 2 2 2 0 V-ATPase subunit H PRP3 PF08572.10 CCU98303.1 - 6.4e-60 202.7 5.2 1.2e-59 201.7 5.2 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CCU98303.1 - 5.2e-38 130.4 0.0 1.1e-37 129.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) TRAUB PF08164.12 CCU98304.1 - 1e-23 83.6 3.5 3.1e-23 82.1 0.0 3.0 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 CCU98304.1 - 6.5e-20 72.2 0.3 6.5e-20 72.2 0.3 3.0 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor Mpp10 PF04006.12 CCU98304.1 - 2.3 6.6 32.3 4.1 5.7 32.3 1.3 1 0 0 1 1 1 0 Mpp10 protein GTP_cyclohydro2 PF00925.20 CCU98305.1 - 1.3e-63 213.5 0.1 1.5e-62 210.0 0.0 2.4 2 1 0 2 2 2 1 GTP cyclohydrolase II LRR_1 PF00560.33 CCU98306.1 - 0.006 17.0 0.0 1.9 9.3 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 CCU98306.1 - 0.0065 16.4 0.0 0.067 13.3 0.0 2.7 2 0 0 2 2 2 1 Leucine Rich repeat F-box-like PF12937.7 CCU98306.1 - 0.39 10.6 1.8 1.2 9.1 1.8 1.9 1 1 0 1 1 1 0 F-box-like Hydrolase_4 PF12146.8 CCU98307.1 - 7.8e-11 41.7 0.0 5.8e-09 35.6 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCU98307.1 - 8.6e-11 42.9 0.0 1.8e-10 41.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CCU98307.1 - 1.3e-10 41.4 0.0 4.4e-09 36.4 0.0 2.5 2 1 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CCU98307.1 - 4.4e-07 30.0 0.0 1e-06 28.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 CCU98307.1 - 0.02 14.5 0.0 0.047 13.3 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 CCU98307.1 - 0.029 14.2 0.0 1.9 8.2 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 CCU98307.1 - 0.045 13.9 0.1 0.12 12.5 0.0 1.8 2 1 0 2 2 2 0 Thioesterase domain DUF5543 PF17697.1 CCU98307.1 - 0.16 12.3 0.0 0.46 10.8 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5543) Abhydrolase_9 PF10081.9 CCU98307.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta-hydrolase family FDX-ACB PF03147.14 CCU98308.1 - 3.2e-27 94.8 0.1 9e-27 93.3 0.0 1.7 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2d PF01409.20 CCU98308.1 - 2.5e-26 92.6 0.0 4.7e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) NAPRTase_C PF17956.1 CCU98308.1 - 0.051 14.0 0.1 0.1 13.0 0.1 1.4 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain Syntaxin_2 PF14523.6 CCU98309.1 - 1.2 9.6 4.5 1.8 9.0 0.9 2.4 2 0 0 2 2 2 0 Syntaxin-like protein DOT1 PF08123.13 CCU98310.1 - 4.1e-29 101.6 0.0 5.2e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 baeRF_family3 PF18845.1 CCU98310.1 - 0.06 13.6 0.1 0.5 10.6 0.0 2.3 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 3 Pkinase PF00069.25 CCU98311.1 - 2e-43 148.7 0.2 4.7e-22 78.6 0.6 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98311.1 - 6.7e-10 38.7 3.1 1.5e-09 37.6 0.2 2.3 2 1 1 3 3 3 1 Protein tyrosine kinase Zein-binding PF04576.15 CCU98311.1 - 0.051 13.9 2.4 0.091 13.1 1.2 2.0 2 0 0 2 2 2 0 Zein-binding PigN PF04987.14 CCU98312.1 - 8.5e-100 334.8 17.3 1.1e-99 334.4 17.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CCU98312.1 - 6.5e-10 39.1 0.6 3.2e-06 27.0 0.1 3.0 2 1 1 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CCU98312.1 - 3.5e-06 26.7 0.1 5.8e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CCU98312.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Not1 PF04054.15 CCU98313.1 - 1e-103 347.1 0.4 2.5e-103 345.8 0.4 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CCU98313.1 - 4.2e-86 288.0 0.3 2.8e-85 285.3 0.1 2.2 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 CCU98313.1 - 2.3e-55 186.6 2.8 6.7e-55 185.1 2.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 CCU98313.1 - 1.2e-52 177.9 0.0 5.1e-52 175.8 0.0 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 CCU98313.1 - 2.6e-37 128.2 1.0 8.5e-37 126.5 1.0 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat FANCI_S2 PF14676.6 CCU98313.1 - 0.0035 17.7 0.7 0.07 13.4 0.0 3.2 3 1 0 3 3 3 1 FANCI solenoid 2 ABC_membrane PF00664.23 CCU98314.1 - 7.2e-25 88.2 4.7 1.1e-24 87.5 4.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CCU98314.1 - 4.1e-10 40.3 0.0 1.3e-09 38.7 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane_2 PF06472.15 CCU98314.1 - 0.0016 17.9 0.5 0.0016 17.9 0.5 2.3 4 0 0 4 4 4 1 ABC transporter transmembrane region 2 DUF4913 PF16259.5 CCU98314.1 - 0.0091 16.0 0.3 0.021 14.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4913) SbmA_BacA PF05992.12 CCU98314.1 - 0.12 11.8 4.7 1 8.7 0.1 2.3 2 0 0 2 2 2 0 SbmA/BacA-like family ABC_tran PF00005.27 CCU98315.1 - 2e-30 106.1 0.0 2.7e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CCU98315.1 - 8.2e-07 28.7 0.0 0.00037 20.0 0.0 2.0 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CCU98315.1 - 0.0012 19.1 0.3 0.032 14.5 0.3 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CCU98315.1 - 0.0017 18.2 0.1 1.4 8.6 0.0 2.1 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.6 CCU98315.1 - 0.0018 18.7 0.1 0.0027 18.1 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 CCU98315.1 - 0.0038 17.1 0.8 0.22 11.3 0.3 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 CCU98315.1 - 0.0043 16.8 0.0 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CCU98315.1 - 0.0047 16.6 0.0 0.0099 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CCU98315.1 - 0.018 15.1 0.1 0.066 13.3 0.1 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase DEAD PF00270.29 CCU98315.1 - 0.021 14.6 0.0 6.3 6.5 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF87 PF01935.17 CCU98315.1 - 0.031 14.4 0.3 0.096 12.8 0.1 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 CCU98315.1 - 0.2 12.1 0.0 0.31 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Aminotran_4 PF01063.19 CCU98316.1 - 7.3e-31 107.8 0.0 9.4e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV WD40 PF00400.32 CCU98317.1 - 0.00044 21.0 11.3 0.17 12.8 0.3 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat DEAD PF00270.29 CCU98318.1 - 9.4e-46 155.8 0.0 9.1e-45 152.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU98318.1 - 7.3e-20 71.4 0.0 1.6e-16 60.6 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCU98318.1 - 5.2e-05 23.3 1.2 0.00046 20.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCU98318.1 - 0.022 13.9 0.0 0.022 13.9 0.0 2.2 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CCU98318.1 - 0.045 13.1 0.0 0.045 13.1 0.0 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AP3D1 PF06375.11 CCU98318.1 - 2.1 8.6 19.6 4.5 7.5 19.6 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Draxin PF15550.6 CCU98318.1 - 3.1 7.6 10.9 2.8 7.7 8.8 1.7 2 0 0 2 2 2 0 Draxin CH PF00307.31 CCU98319.1 - 3.8e-78 258.7 0.2 8.4e-19 67.8 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CCU98319.1 - 5.4e-08 32.6 0.0 0.12 12.2 0.0 4.4 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.6 CCU98319.1 - 8.3e-05 23.0 1.7 0.00017 22.0 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair CH_2 PF06294.11 CCU98319.1 - 0.12 12.5 0.0 33 4.7 0.0 3.1 3 0 0 3 3 3 0 CH-like domain in sperm protein SPX PF03105.19 CCU98320.1 - 9.6e-15 55.4 1.9 9.6e-15 55.4 1.9 1.8 1 1 1 2 2 2 1 SPX domain CitMHS PF03600.16 CCU98320.1 - 1e-13 51.2 18.6 2.1e-13 50.2 18.6 1.4 1 1 0 1 1 1 1 Citrate transporter Na_sulph_symp PF00939.19 CCU98320.1 - 6.6e-09 35.3 13.0 2.4e-07 30.2 8.3 2.1 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region TFIIA_gamma_N PF02268.16 CCU98320.1 - 0.041 13.9 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain PseudoU_synth_1 PF01416.20 CCU98321.1 - 6.3e-25 87.7 0.0 2.7e-21 76.1 0.0 3.3 3 0 0 3 3 3 2 tRNA pseudouridine synthase SET PF00856.28 CCU98322.1 - 2.6e-08 34.4 0.0 6.9e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 SET domain NUDIX PF00293.28 CCU98323.1 - 3.2e-22 79.0 0.0 4.6e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Rnk_N PF14760.6 CCU98323.1 - 0.047 14.2 1.7 1.6 9.3 0.3 2.4 2 0 0 2 2 2 0 Rnk N-terminus Asp PF00026.23 CCU98324.1 - 8.8e-43 146.9 9.7 4.6e-42 144.6 9.7 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 CCU98324.1 - 4.4e-09 36.9 1.6 8.2e-05 23.2 0.3 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CCU98324.1 - 2.1e-06 28.2 0.6 0.0042 17.6 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 CCU98324.1 - 0.00089 19.1 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 CCU98324.1 - 0.00098 19.4 1.7 0.0058 16.9 1.4 2.2 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal DAHP_synth_2 PF01474.16 CCU98325.1 - 7.7e-192 637.6 0.0 8.7e-192 637.4 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Rv2175c_C PF18367.1 CCU98325.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Rv2175c C-terminal domain of unknown function Sec34 PF04136.15 CCU98326.1 - 2.2e-25 89.3 0.1 6.3e-25 87.8 0.1 1.7 1 0 0 1 1 1 1 Sec34-like family Takusan PF04822.13 CCU98326.1 - 0.0064 16.3 1.1 0.5 10.3 0.1 3.4 3 0 0 3 3 3 1 Takusan YabA PF06156.13 CCU98326.1 - 0.094 13.4 0.2 24 5.6 0.2 2.6 2 0 0 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 CCU98326.1 - 0.39 11.2 2.8 2.5 8.7 0.4 3.0 3 0 0 3 3 3 0 Apg6 coiled-coil region ZapB PF06005.12 CCU98326.1 - 2.4 8.6 4.9 46 4.6 0.0 3.3 3 0 0 3 3 3 0 Cell division protein ZapB SKA2 PF16740.5 CCU98326.1 - 2.8 7.8 5.6 2.3 8.0 0.3 3.3 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 2 Ribosomal_L6 PF00347.23 CCU98328.1 - 7.6e-24 84.2 2.5 5.3e-15 55.9 0.1 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 KH_1 PF00013.29 CCU98328.1 - 0.025 14.4 2.6 12 5.9 0.1 3.3 2 1 1 3 3 3 0 KH domain Ribosomal_L37e PF01907.19 CCU98329.1 - 1.9e-07 31.1 3.6 1.9e-07 31.1 3.6 2.4 2 2 1 3 3 3 1 Ribosomal protein L37e DUF1462 PF07315.11 CCU98329.1 - 0.038 14.3 0.0 0.044 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Ribosomal_L7Ae PF01248.26 CCU98330.1 - 5.8e-23 80.5 0.0 6.6e-23 80.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FKBP_C PF00254.28 CCU98330.1 - 0.035 14.4 0.1 0.088 13.1 0.0 1.6 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase Cyclin_N PF00134.23 CCU98331.1 - 4.3e-22 78.2 0.1 6.4e-22 77.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain AbiJ_NTD3 PF18860.1 CCU98331.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AbiJ N-terminal domain 3 MBF1 PF08523.10 CCU98333.1 - 2.5e-21 75.9 0.3 4.7e-21 75.0 0.3 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CCU98333.1 - 3.1e-12 46.4 0.2 4.8e-12 45.7 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 CCU98333.1 - 1.5e-06 28.4 0.0 3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CCU98333.1 - 5.9e-05 23.0 0.1 8.7e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Pkinase PF00069.25 CCU98334.1 - 3.8e-61 206.8 0.0 8.7e-60 202.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98334.1 - 2.6e-31 108.8 0.0 1.3e-29 103.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU98334.1 - 8.4e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CCU98334.1 - 6.6e-05 21.9 0.1 0.00027 19.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CCU98334.1 - 0.00055 19.3 0.3 0.0019 17.6 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCU98334.1 - 0.013 15.4 0.1 1.2 9.0 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 CCU98334.1 - 0.066 12.8 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 JAB PF01398.21 CCU98335.1 - 7.9e-23 80.7 0.0 1.4e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CCU98335.1 - 3.6e-16 59.6 0.1 7.9e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prefoldin_2 PF01920.20 CCU98335.1 - 0.024 14.6 0.2 0.042 13.8 0.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit Methyltransf_4 PF02390.17 CCU98336.1 - 2.4e-53 180.1 0.0 1.3e-39 135.4 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_25 PF13649.6 CCU98336.1 - 0.00015 22.4 0.0 0.017 15.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CCU98336.1 - 0.0002 21.0 0.0 0.0056 16.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CCU98336.1 - 0.0019 18.9 0.0 0.0057 17.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCU98336.1 - 0.013 16.2 0.0 1.5 9.5 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 CCU98336.1 - 0.03 14.3 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF913 PF06025.12 CCU98336.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3492 PF11997.8 CCU98337.1 - 0.035 13.8 0.0 0.039 13.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) NDUFB10 PF10249.9 CCU98337.1 - 0.037 14.5 0.3 0.041 14.4 0.3 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Prefoldin_2 PF01920.20 CCU98338.1 - 2.7e-18 65.9 7.5 3.4e-18 65.5 7.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 CCU98338.1 - 0.0019 18.1 5.5 0.0037 17.2 5.5 1.3 1 1 0 1 1 1 1 Prefoldin subunit Mei5 PF10376.9 CCU98338.1 - 0.012 15.5 1.3 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Double-strand recombination repair protein NOC3p PF07540.11 CCU98338.1 - 0.042 14.3 0.2 0.058 13.9 0.2 1.3 1 0 0 1 1 1 0 Nucleolar complex-associated protein Thiamine_BP PF01910.17 CCU98338.1 - 0.052 13.5 0.5 1.3 9.0 0.2 2.2 2 0 0 2 2 2 0 Thiamine-binding protein DUF4259 PF14078.6 CCU98338.1 - 0.062 14.1 0.8 0.075 13.8 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) DUF641 PF04859.12 CCU98338.1 - 0.18 12.1 7.2 0.16 12.3 1.7 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) PC_rep PF01851.22 CCU98339.1 - 7.9e-43 142.8 22.8 3.9e-09 36.5 0.1 9.4 9 0 0 9 9 9 7 Proteasome/cyclosome repeat RPN2_C PF18004.1 CCU98339.1 - 9.1e-39 132.9 0.6 8.7e-38 129.8 0.6 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 CCU98339.1 - 1.1e-17 64.1 17.0 6.2e-13 48.9 0.1 5.8 4 2 1 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 CCU98339.1 - 3.1e-06 27.5 6.1 2.4 8.8 0.0 6.1 6 0 0 6 6 6 3 HEAT-like repeat RPN1_RPN2_N PF17781.1 CCU98339.1 - 0.0011 18.5 2.5 0.003 17.0 2.5 1.7 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain HEAT PF02985.22 CCU98339.1 - 0.0051 17.0 6.3 1.4 9.4 0.1 4.9 5 0 0 5 5 5 2 HEAT repeat Telomere_reg-2 PF10193.9 CCU98339.1 - 0.036 14.5 1.4 0.75 10.3 0.0 3.2 3 0 0 3 3 3 0 Telomere length regulation protein HEAT_PBS PF03130.16 CCU98339.1 - 1.1 10.1 12.0 94 4.1 0.0 5.8 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat TPR_5 PF12688.7 CCU98339.1 - 6.9 6.9 7.7 26 5.1 0.0 4.8 3 1 2 5 5 5 0 Tetratrico peptide repeat Actin PF00022.19 CCU98341.1 - 1.9e-21 76.2 0.0 7e-21 74.3 0.0 1.8 1 1 0 1 1 1 1 Actin Pyridox_ox_2 PF12900.7 CCU98341.1 - 0.023 14.7 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase PGM_PMM_I PF02878.16 CCU98342.1 - 4.9e-15 55.5 0.1 2.6e-08 33.7 0.0 2.9 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CCU98342.1 - 3.4e-09 36.7 0.2 7.5e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 CCU98342.1 - 0.00073 19.7 0.3 0.0023 18.1 0.3 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CCU98342.1 - 0.0033 18.0 0.1 0.033 14.8 0.1 2.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II POR_N PF01855.19 CCU98342.1 - 0.068 12.9 0.0 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PQ-loop PF04193.14 CCU98343.1 - 1.3e-24 85.7 3.4 5.5e-13 48.5 0.3 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 CCU98343.1 - 0.0016 18.4 3.3 0.025 14.6 0.6 2.4 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange DUF1856 PF08983.10 CCU98343.1 - 0.057 13.6 1.2 0.46 10.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) DUF1600 PF07667.11 CCU98343.1 - 0.78 10.0 4.3 4.1 7.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) Apq12 PF12716.7 CCU98343.1 - 3.3 7.7 6.6 0.33 10.9 0.6 2.5 3 0 0 3 3 3 0 Nuclear pore assembly and biogenesis MFS_1 PF07690.16 CCU98344.1 - 2e-08 33.6 24.7 2.9e-08 33.0 24.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily BESS PF02944.20 CCU98344.1 - 0.093 12.6 1.0 0.32 10.9 0.0 2.3 3 0 0 3 3 3 0 BESS motif JAB PF01398.21 CCU98345.1 - 5e-10 39.4 0.0 1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HCV_NS2 PF01538.18 CCU98345.1 - 0.15 11.7 0.2 0.36 10.4 0.2 1.6 1 1 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 bVLRF1 PF18826.1 CCU98346.1 - 3.1e-44 150.5 0.8 5.2e-44 149.7 0.2 1.8 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor LAG1-DNAbind PF09271.11 CCU98347.1 - 3.8e-23 82.8 0.0 3.3e-21 76.5 0.0 2.3 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 CCU98347.1 - 2.9e-18 66.6 0.0 5.8e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF501 PF04417.12 CCU98347.1 - 0.00092 19.0 0.2 0.0019 18.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF501) Las1 PF04031.13 CCU98348.1 - 4e-44 150.4 2.1 1.6e-43 148.5 0.2 2.2 2 0 0 2 2 2 1 Las1-like 3-alpha PF03475.14 CCU98348.1 - 0.36 10.7 0.1 0.36 10.7 0.1 2.8 2 0 0 2 2 2 0 3-alpha domain SAICAR_synt PF01259.18 CCU98349.1 - 7.6e-90 300.9 0.0 1e-89 300.5 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Kinesin PF00225.23 CCU98350.1 - 2.3e-101 339.1 0.0 4e-101 338.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CCU98350.1 - 4.1e-21 75.5 0.0 9.7e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 CCU98350.1 - 0.09 12.6 0.1 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 Bacterial dnaA protein EzrA PF06160.12 CCU98350.1 - 0.56 8.3 10.3 2.6 6.1 10.3 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Glutaredoxin2_C PF04399.13 CCU98350.1 - 2 8.3 5.2 0.68 9.8 0.1 2.9 3 1 1 4 4 4 0 Glutaredoxin 2, C terminal domain WD40 PF00400.32 CCU98351.1 - 7.4e-43 143.7 18.1 9.1e-08 32.7 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU98351.1 - 2.1e-17 63.2 0.2 0.00016 21.9 0.0 5.2 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCU98351.1 - 6e-07 29.5 0.0 0.0013 18.7 0.0 3.8 2 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCU98351.1 - 1e-05 24.7 4.8 0.094 11.7 0.1 4.0 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CCU98351.1 - 5e-05 22.8 0.0 0.049 13.0 0.0 3.1 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 CCU98351.1 - 0.00055 18.7 7.5 0.31 9.7 0.0 3.8 2 2 2 4 4 4 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CCU98351.1 - 0.011 14.7 0.3 0.54 9.1 0.0 2.5 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain VID27 PF08553.10 CCU98351.1 - 0.024 13.7 0.0 10 5.1 0.0 2.9 2 1 0 3 3 3 0 VID27 C-terminal WD40-like domain DBP10CT PF08147.12 CCU98351.1 - 0.12 12.6 0.1 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 DBP10CT (NUC160) domain Rnk_N PF14760.6 CCU98352.1 - 2 8.9 4.9 0.98 10.0 1.8 1.9 2 0 0 2 2 2 0 Rnk N-terminus Aminotran_1_2 PF00155.21 CCU98353.1 - 2.5e-47 161.8 0.0 4.5e-47 161.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CCU98353.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CCU98353.1 - 0.15 10.6 0.0 0.33 9.4 0.0 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 CCU98353.1 - 0.25 9.9 0.3 1.6 7.3 0.3 1.9 2 0 0 2 2 2 0 Aminotransferase class-III DUF3818 PF12825.7 CCU98354.1 - 3.2e-50 171.1 0.1 3.2e-50 171.1 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CCU98354.1 - 4e-20 72.1 0.2 4e-19 68.9 0.5 2.4 2 0 0 2 2 2 1 PX-associated DUF3500 PF12006.8 CCU98354.1 - 0.014 14.9 0.7 0.027 14.0 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3500) DUF2433 PF10360.9 CCU98355.1 - 7.3e-36 123.0 0.0 1.3e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 CCU98355.1 - 0.028 14.3 0.0 0.14 12.0 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 CCU98355.1 - 0.13 12.7 0.0 0.42 11.1 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase GTP_EFTU PF00009.27 CCU98356.1 - 1.3e-36 125.9 0.0 4.7e-36 124.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CCU98356.1 - 1.1e-17 64.1 0.0 2.6e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CCU98356.1 - 3e-16 59.6 3.2 8.8e-11 42.1 0.1 3.8 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCU98356.1 - 8.6e-06 25.8 0.0 4.9e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CCU98356.1 - 0.0017 18.2 0.0 0.0045 16.8 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Roc PF08477.13 CCU98356.1 - 0.0025 18.0 0.0 0.0063 16.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CCU98356.1 - 0.014 15.5 0.2 0.014 15.5 0.2 3.1 3 0 0 3 3 3 0 Dynamin family GTP_EFTU_D4 PF14578.6 CCU98356.1 - 0.025 14.5 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Ras PF00071.22 CCU98356.1 - 0.11 12.1 0.0 0.37 10.4 0.0 1.9 1 1 0 1 1 1 0 Ras family SRPRB PF09439.10 CCU98356.1 - 0.43 10.0 0.0 0.43 10.0 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit MAM33 PF02330.16 CCU98360.1 - 1.5e-67 227.6 1.3 1.8e-67 227.4 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein RICTOR_N PF14664.6 CCU98362.1 - 2.5e-27 95.8 0.3 2.1e-22 79.7 0.2 3.3 1 1 1 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 CCU98362.1 - 9.7e-24 83.1 0.1 2.2e-21 75.6 0.0 3.7 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 CCU98362.1 - 1e-21 76.9 1.5 8.1e-20 70.8 0.1 4.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 CCU98362.1 - 5.4e-17 62.2 0.2 4.9e-16 59.1 0.0 2.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.23 CCU98362.1 - 0.0037 17.3 1.0 0.031 14.3 0.1 3.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Methyltransf_28 PF02636.17 CCU98365.1 - 1.1e-35 123.5 0.0 2.1e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MMgT PF10270.9 CCU98365.1 - 1.1e-12 48.1 0.0 4e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Membrane magnesium transporter Methyltransf_12 PF08242.12 CCU98365.1 - 0.0018 19.0 0.0 0.0086 16.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 CCU98365.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Actin PF00022.19 CCU98366.1 - 4.8e-148 493.1 0.0 2.3e-147 490.9 0.0 1.8 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 CCU98366.1 - 0.0049 15.5 0.0 0.0071 15.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Nop PF01798.18 CCU98367.1 - 1.7e-84 282.9 0.0 1.7e-84 282.9 0.0 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CCU98367.1 - 6.6e-17 61.6 0.1 6.6e-17 61.6 0.1 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Sigma70_ner PF04546.13 CCU98367.1 - 0.23 11.3 14.4 0.5 10.2 14.4 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region GAGA_bind PF06217.12 CCU98367.1 - 2.9 8.1 12.7 4.5 7.5 12.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 CCU98367.1 - 7.3 6.3 21.1 14 5.4 21.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CENP-N PF05238.13 CCU98367.1 - 7.7 5.7 11.5 11 5.2 11.5 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Proteasome PF00227.26 CCU98368.1 - 3.9e-47 160.2 0.5 2.3e-45 154.4 0.3 2.5 2 1 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 CCU98368.1 - 6.6e-15 54.5 0.1 6.6e-15 54.5 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature TPR_16 PF13432.6 CCU98369.1 - 2.2e-05 25.0 28.4 0.001 19.7 7.8 14.6 15 3 2 18 18 18 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCU98369.1 - 7.7e-05 22.4 15.5 0.12 12.2 0.0 7.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCU98369.1 - 9.6e-05 22.2 48.2 0.019 15.1 0.0 11.8 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_14 PF13428.6 CCU98369.1 - 0.00075 20.1 11.4 0.0014 19.3 3.4 15.9 11 4 6 17 17 17 3 Tetratricopeptide repeat TPR_6 PF13174.6 CCU98369.1 - 0.0089 16.6 0.1 0.0089 16.6 0.1 10.2 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCU98369.1 - 0.025 14.8 8.8 2.4 8.6 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 CCU98369.1 - 0.027 14.1 14.6 0.43 10.3 0.0 6.6 7 0 0 7 7 7 0 TPR repeat TPR_17 PF13431.6 CCU98369.1 - 0.17 12.3 12.4 33 5.2 0.0 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat SNO PF01174.19 CCU98370.1 - 2.1e-50 171.2 0.0 2.3e-47 161.3 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 CCU98370.1 - 2.2e-11 43.8 0.0 3.3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 CCU98370.1 - 4.6e-05 23.2 0.0 7.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 CCU98370.1 - 0.00012 21.9 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 CCU98370.1 - 0.00053 19.8 0.0 0.054 13.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CCU98370.1 - 0.024 14.4 0.1 0.29 10.9 0.1 2.4 3 0 0 3 3 3 0 Peptidase C26 BPL_N PF09825.9 CCU98370.1 - 0.12 11.4 0.0 0.47 9.5 0.0 1.8 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal ThiJ_like PF17124.5 CCU98370.1 - 0.13 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like MT-A70 PF05063.14 CCU98371.1 - 2.7e-11 43.7 0.0 3.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 MT-A70 FAD-oxidase_C PF02913.19 CCU98371.1 - 0.022 14.4 0.2 0.034 13.8 0.2 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Cpn60_TCP1 PF00118.24 CCU98372.1 - 3.3e-148 494.4 9.8 3.7e-148 494.2 9.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 CCU98372.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat COX4 PF02936.14 CCU98373.1 - 5.5e-25 88.0 0.3 2.9e-24 85.7 0.3 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase subunit IV HMG_box_5 PF14887.6 CCU98373.1 - 0.055 13.4 0.3 0.1 12.6 0.3 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Cys_Met_Meta_PP PF01053.20 CCU98374.1 - 1.2e-141 471.7 0.0 1.4e-141 471.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CCU98374.1 - 1e-10 41.1 0.3 8.2e-10 38.2 0.3 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CCU98374.1 - 1e-10 41.5 0.1 2.2e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CCU98374.1 - 5.2e-10 39.0 0.0 6.8e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CCU98374.1 - 6.9e-07 28.8 0.0 1.8e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aldo_ket_red PF00248.21 CCU98374.1 - 0.048 12.9 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Aldo/keto reductase family Met_gamma_lyase PF06838.11 CCU98374.1 - 0.075 11.5 0.3 0.3 9.5 0.3 1.8 1 1 0 1 1 1 0 Methionine gamma-lyase SepSecS PF05889.13 CCU98374.1 - 0.084 11.6 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS RalF_SCD PF18248.1 CCU98374.1 - 0.097 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 RalF C-terminal Sec-7 capping domain Cys_Met_Meta_PP PF01053.20 CCU98375.1 - 3.8e-118 394.4 0.0 5.7e-118 393.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RTC PF01137.21 CCU98375.1 - 4.4e-48 163.4 0.0 7.3e-48 162.7 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CCU98375.1 - 1.6e-35 121.7 0.1 8.3e-35 119.4 0.0 2.4 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain GHMP_kinases_N PF00288.26 CCU98375.1 - 1.7e-14 53.8 1.1 7.3e-14 51.8 1.1 2.2 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCU98375.1 - 5.2e-06 26.7 0.9 1.2e-05 25.6 0.2 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 CCU98375.1 - 0.0028 17.2 0.1 0.0064 16.0 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Met_gamma_lyase PF06838.11 CCU98375.1 - 0.047 12.2 0.0 0.1 11.1 0.0 1.4 1 1 0 1 1 1 0 Methionine gamma-lyase Aminotran_1_2 PF00155.21 CCU98375.1 - 0.066 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II DUF2347 PF09804.9 CCU98376.1 - 2.7e-31 109.2 0.0 8.4e-29 101.0 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 CCU98376.1 - 0.2 10.3 0.0 4 6.0 0.1 2.6 3 0 0 3 3 3 0 Transport protein Avl9 MFAP1 PF06991.11 CCU98377.1 - 1.1e-57 195.4 15.2 1.3e-57 195.2 15.2 1.1 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing DUF4407 PF14362.6 CCU98377.1 - 3.2 7.0 11.8 4.8 6.5 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Arf PF00025.21 CCU98378.1 - 2.8e-24 85.5 0.0 3.3e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CCU98378.1 - 3e-07 29.9 0.1 3e-06 26.6 0.0 1.9 1 1 1 2 2 2 1 G-protein alpha subunit Roc PF08477.13 CCU98378.1 - 2e-05 24.8 0.0 2.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CCU98378.1 - 5.9e-05 22.6 0.0 6.9e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CCU98378.1 - 0.038 13.6 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 Ras family Gtr1_RagA PF04670.12 CCU98378.1 - 0.067 12.5 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF1501 PF07394.12 CCU98378.1 - 0.086 11.9 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) MMR_HSR1 PF01926.23 CCU98378.1 - 0.19 11.8 0.1 0.42 10.7 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase SNF2_N PF00176.23 CCU98379.1 - 4.6e-61 206.5 0.0 4.6e-61 206.5 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCU98379.1 - 1.6e-19 70.3 0.6 1.8e-18 66.9 0.1 2.9 3 1 1 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU98379.1 - 8.2e-11 42.2 0.0 2.3e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 CCU98379.1 - 7.8e-10 38.9 10.4 7.8e-10 38.9 10.4 2.5 3 0 0 3 3 3 1 HSA DEAD PF00270.29 CCU98379.1 - 8.1e-05 22.5 0.0 0.00056 19.7 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 CCU98379.1 - 0.038 13.2 0.2 2.4 7.2 0.0 2.6 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 BUD22 PF09073.10 CCU98379.1 - 2.4 7.4 36.2 0.027 13.8 28.3 1.6 2 0 0 2 2 2 0 BUD22 ATP-synt_Eps PF04627.13 CCU98380.1 - 2.3e-13 49.9 6.2 3.2e-13 49.4 6.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain CDC50 PF03381.15 CCU98382.1 - 3.2e-82 276.2 0.0 3.9e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family GTP_EFTU PF00009.27 CCU98383.1 - 3.4e-22 78.9 0.0 5.8e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CCU98383.1 - 6.2e-07 29.7 0.1 6e-06 26.5 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCU98383.1 - 0.0031 17.6 0.0 0.01 15.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 CCU98383.1 - 0.0071 16.6 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain FeoB_N PF02421.18 CCU98383.1 - 0.078 12.5 0.1 4.7 6.7 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Oxysterol_BP PF01237.18 CCU98385.1 - 5e-76 256.0 0.0 6.4e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein TPR_1 PF00515.28 CCU98386.1 - 3.2e-55 181.8 14.7 1.6e-05 24.5 0.1 10.4 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 CCU98386.1 - 2.4e-49 161.5 9.5 3e-05 23.8 0.1 10.3 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 CCU98386.1 - 5.7e-40 132.2 8.5 1.8e-05 24.6 0.0 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.6 CCU98386.1 - 3.7e-33 111.4 2.9 0.00093 19.8 0.0 10.2 3 3 7 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 CCU98386.1 - 1.3e-29 102.5 4.0 4.2e-05 24.0 0.1 6.7 4 1 1 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 CCU98386.1 - 3.5e-26 89.3 15.3 0.0026 17.7 0.0 9.9 9 1 1 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 CCU98386.1 - 1.7e-25 89.4 2.8 0.00021 21.9 0.0 8.1 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 CCU98386.1 - 3.1e-22 78.6 15.1 0.0015 18.8 0.0 7.6 5 3 1 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 CCU98386.1 - 4.2e-21 73.7 11.6 0.027 14.9 0.0 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_6 PF13174.6 CCU98386.1 - 3e-19 68.3 9.4 0.012 16.2 0.0 9.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 CCU98386.1 - 5.3e-16 58.5 8.5 0.00072 19.6 0.0 6.5 3 2 3 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 CCU98386.1 - 3.5e-13 49.0 29.8 8.9e-06 25.3 0.0 9.0 4 2 5 9 9 9 4 TPR repeat ANAPC3 PF12895.7 CCU98386.1 - 6.3e-08 32.7 8.2 0.0011 19.1 0.9 4.2 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CCU98386.1 - 3.4e-07 29.7 4.5 0.69 9.1 0.0 5.1 1 1 3 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 CCU98386.1 - 8.4e-07 28.9 0.6 0.14 11.8 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CCU98386.1 - 7.2e-05 22.5 18.0 2.1 8.3 0.0 8.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 CCU98386.1 - 0.011 16.1 1.2 1.2 9.5 0.2 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2989 PF11207.8 CCU98386.1 - 0.02 14.7 1.6 2.3 7.9 2.0 3.5 3 2 1 4 4 4 0 Protein of unknown function (DUF2989) ChAPs PF09295.10 CCU98386.1 - 0.069 12.1 0.1 3.1 6.7 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2225 PF09986.9 CCU98386.1 - 0.086 12.6 1.3 3 7.5 0.0 2.7 1 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_3 PF07720.12 CCU98386.1 - 0.63 10.1 11.2 5.6 7.1 0.8 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat SNAP PF14938.6 CCU98386.1 - 0.91 8.9 5.8 17 4.7 0.7 4.1 2 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP SOR_SNZ PF01680.17 CCU98387.1 - 7.3e-114 378.7 5.0 1.4e-113 377.8 5.0 1.5 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 CCU98387.1 - 2.7e-06 26.9 7.6 7.4e-05 22.2 0.4 2.7 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 CCU98387.1 - 0.007 15.5 0.6 3.1 6.8 0.1 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 CCU98387.1 - 0.0097 16.0 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 CCU98387.1 - 0.024 13.8 0.4 0.13 11.5 0.0 2.3 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 CCU98387.1 - 0.035 13.5 5.4 0.3 10.4 0.2 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase IGPS PF00218.21 CCU98387.1 - 0.062 12.5 0.1 0.97 8.5 0.0 2.3 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase RNA_pol_Rpc4 PF05132.14 CCU98387.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Rieske PF00355.26 CCU98388.1 - 5.8e-11 42.2 0.0 9.9e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 CCU98388.1 - 1.1e-08 35.4 0.6 4.2e-08 33.5 0.6 2.1 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region HEAT PF02985.22 CCU98390.1 - 1.9e-05 24.5 18.7 0.68 10.3 0.0 9.1 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.6 CCU98390.1 - 2.7e-05 24.5 4.6 0.35 11.3 0.0 5.1 3 2 1 5 5 5 2 HEAT repeats Adaptin_N PF01602.20 CCU98390.1 - 0.024 13.2 0.0 0.11 11.0 0.0 1.9 2 0 0 2 2 2 0 Adaptin N terminal region OPT PF03169.15 CCU98391.1 - 8.2e-89 298.9 45.7 1.7e-81 274.8 39.0 2.5 1 1 1 2 2 2 2 OPT oligopeptide transporter protein DUF1270 PF06900.11 CCU98391.1 - 0.0033 17.8 0.7 0.0033 17.8 0.7 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1270) SelK_SelG PF10961.8 CCU98391.1 - 0.4 11.3 0.1 0.4 11.3 0.1 2.1 2 0 0 2 2 2 0 Selenoprotein SelK_SelG PDEase_II PF02112.15 CCU98392.1 - 2.8e-48 164.8 0.0 4.4e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 CCU98392.1 - 2.1e-06 27.4 0.0 5.4e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CCU98392.1 - 0.0061 16.6 0.3 0.029 14.4 0.1 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily GATase_2 PF00310.21 CCU98393.1 - 7.3e-169 561.9 0.0 9.6e-169 561.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 CCU98393.1 - 8.1e-156 518.8 0.0 1.4e-155 518.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CCU98393.1 - 5e-114 380.5 0.0 1.5e-112 375.7 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 CCU98393.1 - 1.3e-84 282.6 0.9 2e-84 281.9 0.9 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 CCU98393.1 - 1.4e-26 93.4 0.0 2.1e-25 89.6 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 CCU98393.1 - 1.8e-20 72.8 0.0 3.6e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 CCU98393.1 - 1.2e-09 38.2 0.1 6.5e-09 35.9 0.1 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CCU98393.1 - 3e-07 30.9 2.2 0.00013 22.4 0.1 3.7 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CCU98393.1 - 4.7e-07 29.5 0.1 1.2e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 CCU98393.1 - 6e-07 29.4 4.0 0.00082 19.0 0.5 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CCU98393.1 - 8.5e-06 25.1 0.5 0.00045 19.4 0.3 3.1 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 CCU98393.1 - 1.7e-05 24.2 0.7 0.0087 15.4 0.0 3.0 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CCU98393.1 - 1.9e-05 23.6 1.8 2.2e-05 23.4 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 CCU98393.1 - 0.00029 20.3 0.7 0.00029 20.3 0.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase AdoHcyase_NAD PF00670.21 CCU98393.1 - 0.00064 19.8 0.3 1.7 8.7 0.2 2.7 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 CCU98393.1 - 0.00073 19.9 0.0 2.5 8.6 0.1 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CCU98393.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 CCU98393.1 - 0.013 14.8 0.0 5.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.18 CCU98393.1 - 0.019 14.0 0.6 0.092 11.8 0.4 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Lycopene_cycl PF05834.12 CCU98393.1 - 0.033 13.2 1.1 0.23 10.5 0.1 2.7 4 0 0 4 4 4 0 Lycopene cyclase protein Thi4 PF01946.17 CCU98393.1 - 0.042 13.1 0.3 0.11 11.8 0.3 1.6 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 CCU98393.1 - 0.044 13.2 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 CCU98393.1 - 0.093 11.8 2.6 0.17 11.0 0.4 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.19 CCU98393.1 - 0.14 10.5 0.1 0.97 7.8 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Nop PF01798.18 CCU98394.1 - 2.5e-67 226.7 0.0 3.6e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CCU98394.1 - 7.1e-37 127.0 2.8 1.2e-36 126.2 2.8 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain TRAM_2 PF18693.1 CCU98394.1 - 0.13 12.4 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 TRAM domain Adenylsucc_synt PF00709.21 CCU98395.1 - 1.1e-173 578.0 0.0 1.3e-173 577.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase CybS PF05328.12 CCU98396.1 - 2.7e-32 111.2 0.1 2.4e-30 104.9 0.0 2.1 2 0 0 2 2 2 2 CybS, succinate dehydrogenase cytochrome B small subunit TFIIS_C PF01096.18 CCU98397.1 - 1.5e-08 34.3 8.6 3.6e-08 33.1 4.2 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CCU98397.1 - 3.9e-05 23.4 2.5 3.9e-05 23.4 2.5 2.8 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit DUF3268 PF11672.8 CCU98397.1 - 0.0013 19.0 1.9 1 9.7 0.0 2.1 2 0 0 2 2 2 2 zinc-finger-containing domain CpXC PF14353.6 CCU98397.1 - 0.036 14.1 6.3 0.22 11.5 0.1 2.9 1 1 2 3 3 3 0 CpXC protein Zn-ribbon_8 PF09723.10 CCU98397.1 - 0.047 13.8 5.5 3.1 8.0 0.0 3.2 3 0 0 3 3 3 0 Zinc ribbon domain T4_baseplate PF12322.8 CCU98397.1 - 0.059 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 T4 bacteriophage base plate protein zf-DNL PF05180.12 CCU98397.1 - 0.15 12.0 3.2 1.1 9.2 0.9 2.4 2 0 0 2 2 2 0 DNL zinc finger zf-ribbon_3 PF13248.6 CCU98397.1 - 0.17 11.4 0.2 0.17 11.4 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.6 CCU98397.1 - 0.19 12.1 3.7 0.64 10.4 1.3 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_10 PF10058.9 CCU98397.1 - 0.39 10.5 9.5 1.9 8.3 5.4 2.5 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF2197 PF09963.9 CCU98397.1 - 0.43 10.9 4.3 1.6 9.1 0.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Elf1 PF05129.13 CCU98397.1 - 0.5 10.4 4.4 7.2 6.7 4.1 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like E1_dh PF00676.20 CCU98398.1 - 1.8e-110 368.6 0.0 2.1e-110 368.4 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CCU98398.1 - 0.00023 20.5 0.1 0.00041 19.6 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 CCU98398.1 - 0.022 14.6 4.2 0.07 12.9 0.8 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 CCU98398.1 - 0.086 11.8 0.2 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain Pribosyltran PF00156.27 CCU98399.1 - 6.3e-07 29.0 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain EC042_2821 PF18740.1 CCU98399.1 - 0.26 11.2 0.0 0.4 10.5 0.0 1.2 1 0 0 1 1 1 0 EC042_2821-lke REase DUF962 PF06127.11 CCU98400.1 - 1.6e-22 79.3 2.4 1.8e-21 76.0 2.4 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF974 PF06159.13 CCU98401.1 - 3e-12 46.9 0.0 2.7e-10 40.5 0.0 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF974) Tti2 PF10521.9 CCU98402.1 - 8.8e-20 71.4 0.0 1.3e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Tti2 family zf-C3HC4_3 PF13920.6 CCU98403.1 - 1.6e-06 27.8 8.7 1.6e-06 27.8 8.7 3.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 CCU98403.1 - 1.7 9.3 29.7 1.2 9.8 0.8 6.3 6 0 0 6 6 6 0 Zinc finger, C2H2 type UPF0020 PF01170.18 CCU98404.1 - 0.00015 21.5 0.1 0.00032 20.4 0.1 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 CCU98404.1 - 0.051 13.3 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 DNA methylase DNA_ligase_A_M PF01068.21 CCU98405.1 - 1.4e-05 24.9 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 CCU98405.1 - 0.00023 21.5 0.0 0.00035 20.9 0.0 1.3 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 CCU98405.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain DNA_ligase_OB_2 PF14743.6 CCU98405.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 DNA ligase OB-like domain Mito_carr PF00153.27 CCU98406.1 - 0.03 14.3 2.0 0.85 9.6 0.2 3.1 3 0 0 3 3 3 0 Mitochondrial carrier protein V-ATPase_H_N PF03224.14 CCU98407.1 - 1.9e-52 178.5 0.0 1.7e-51 175.4 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CCU98407.1 - 7.4e-32 109.9 0.0 1.7e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 V-ATPase subunit H HEAT_2 PF13646.6 CCU98407.1 - 0.0012 19.2 5.5 0.22 11.9 0.6 3.2 2 1 0 2 2 2 2 HEAT repeats Arm PF00514.23 CCU98407.1 - 0.087 12.9 6.7 13 6.0 0.2 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CbiG_N PF11760.8 CCU98407.1 - 0.12 12.3 0.3 0.38 10.8 0.1 1.9 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal HEAT PF02985.22 CCU98407.1 - 0.63 10.5 2.4 56 4.4 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat MRP-L46 PF11788.8 CCU98408.1 - 8.6e-15 55.5 2.0 4.7e-14 53.2 2.0 2.0 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 CBS PF00571.28 CCU98409.1 - 2.7e-14 53.3 2.6 0.0093 16.4 0.0 5.7 5 0 0 5 5 5 5 CBS domain Ubiq_cyt_C_chap PF03981.12 CCU98410.1 - 3.6e-29 101.6 0.0 1.5e-28 99.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquinol-cytochrome C chaperone His_biosynth PF00977.21 CCU98411.1 - 1.3e-28 100.0 0.0 1.8e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Nic96 PF04097.14 CCU98412.1 - 2.8e-175 584.3 0.0 3.6e-175 584.0 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 APP_E2 PF12925.7 CCU98412.1 - 0.023 14.4 0.1 0.056 13.1 0.1 1.6 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein TPR_4 PF07721.14 CCU98412.1 - 1.1 10.1 4.9 7.6 7.5 0.2 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 CCU98413.1 - 1.3e-41 142.7 0.1 1.2e-21 77.2 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98413.1 - 2.4e-11 43.4 0.5 2.5e-08 33.5 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Glucosamine_iso PF01182.20 CCU98414.1 - 6.2e-61 206.1 0.0 7.1e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase tRNA-synt_2b PF00587.25 CCU98415.1 - 3e-34 118.6 0.0 6.2e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CCU98415.1 - 1.2e-07 31.8 0.0 4.2e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Anticodon binding domain tRNA-synt_His PF13393.6 CCU98415.1 - 0.18 11.1 0.0 0.38 10.0 0.0 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Nse4_C PF08743.10 CCU98416.1 - 1.8e-16 60.2 0.0 4.5e-16 58.9 0.0 1.7 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 CCU98416.1 - 9.5e-11 41.6 0.9 9.5e-11 41.6 0.9 1.7 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE Arf PF00025.21 CCU98417.1 - 1.5e-72 242.7 0.0 1.8e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCU98417.1 - 5.8e-16 58.8 0.0 7.4e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CCU98417.1 - 8.3e-13 48.3 0.0 9.4e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CCU98417.1 - 1.4e-12 47.4 0.0 1.8e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CCU98417.1 - 6.3e-12 45.3 0.7 7.2e-08 32.0 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CCU98417.1 - 6e-09 35.6 0.0 7.8e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCU98417.1 - 4.5e-06 26.7 0.0 6.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.14 CCU98417.1 - 0.023 14.6 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 6PF2K PF01591.18 CCU98417.1 - 0.029 13.7 0.1 0.045 13.1 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Spc7 PF08317.11 CCU98418.1 - 0.0029 16.5 68.5 0.044 12.7 6.9 4.2 2 1 2 4 4 4 4 Spc7 kinetochore protein Bacillus_HBL PF05791.11 CCU98418.1 - 0.062 13.1 0.1 0.062 13.1 0.1 4.7 2 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Cas_DxTHG PF09455.10 CCU98418.1 - 0.36 10.3 15.1 1.6 8.2 10.9 2.3 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family DUF4988 PF16378.5 CCU98418.1 - 2 8.0 8.0 0.56 9.9 1.5 3.0 2 1 2 4 4 4 0 Domain of unknown function Fib_alpha PF08702.10 CCU98418.1 - 2.6 8.2 37.3 0.11 12.6 2.2 4.6 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 CCU98418.1 - 9.4 6.3 34.2 3.4 7.7 1.3 5.6 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) Lon_C PF05362.13 CCU98419.1 - 2.1e-64 216.8 0.0 3.5e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CCU98419.1 - 1.6e-23 83.6 0.0 3.2e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CCU98419.1 - 1.2e-09 38.3 0.0 3.6e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 CCU98419.1 - 3e-08 33.5 0.0 6.8e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 CCU98419.1 - 3.6e-05 24.2 3.4 5.8e-05 23.5 0.1 2.9 3 2 1 4 4 3 1 AAA ATPase domain AAA_25 PF13481.6 CCU98419.1 - 4.6e-05 23.1 0.1 0.00013 21.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCU98419.1 - 0.00039 20.7 0.0 0.0056 17.0 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CCU98419.1 - 0.00072 19.7 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CCU98419.1 - 0.004 16.6 0.1 0.031 13.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CCU98419.1 - 0.015 15.8 0.0 0.04 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 CCU98419.1 - 0.015 15.4 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 CCU98419.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 CCU98419.1 - 0.02 14.1 0.2 0.067 12.4 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_28 PF13521.6 CCU98419.1 - 0.022 15.0 0.1 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CCU98419.1 - 0.024 14.4 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CCU98419.1 - 0.027 14.2 0.0 0.13 12.0 0.0 2.0 2 1 1 3 3 3 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CCU98419.1 - 0.029 13.6 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.11 CCU98419.1 - 0.03 14.2 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CCU98419.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 CCU98419.1 - 0.036 13.8 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 CCU98419.1 - 0.037 12.9 0.1 0.84 8.5 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain Viral_helicase1 PF01443.18 CCU98419.1 - 0.045 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 CCU98419.1 - 0.048 14.2 0.0 0.43 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CCU98419.1 - 0.049 13.1 0.1 0.22 11.0 0.0 2.1 3 0 0 3 3 3 0 PhoH-like protein RNA_helicase PF00910.22 CCU98419.1 - 0.051 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 CCU98419.1 - 0.052 13.9 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CCU98419.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CCU98419.1 - 0.081 12.6 0.2 0.18 11.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain CPT PF07931.12 CCU98419.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NACHT PF05729.12 CCU98419.1 - 0.12 12.3 0.0 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 CCU98419.1 - 0.14 12.6 0.0 0.42 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 CCU98419.1 - 0.2 10.7 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 tRNA-synt_1c PF00749.21 CCU98420.1 - 7.6e-22 77.6 0.0 8e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c PF00749.21 CCU98421.1 - 1e-32 113.3 0.0 1.6e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF3248 PF11609.8 CCU98421.1 - 0.036 14.0 0.0 0.72 9.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3248) eIF-5_eIF-2B PF01873.17 CCU98422.1 - 3e-39 133.5 0.0 4.9e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 CCU98422.1 - 1.4e-19 70.0 0.1 1.4e-19 70.0 0.1 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Sigma70_ner PF04546.13 CCU98422.1 - 0.00026 21.0 0.0 0.18 11.6 0.0 2.5 2 1 0 2 2 2 1 Sigma-70, non-essential region DNA_RNApol_7kD PF03604.13 CCU98422.1 - 0.081 12.6 2.3 0.16 11.7 2.3 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Astro_capsid_p PF12226.8 CCU98422.1 - 0.095 11.8 11.4 0.14 11.3 5.8 2.2 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Pkinase PF00069.25 CCU98423.1 - 1.9e-42 145.4 0.0 3e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 CCU98423.1 - 1.8e-41 141.3 0.1 3.6e-41 140.3 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 CCU98423.1 - 2.7e-25 89.1 0.0 4.3e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Epimerase PF01370.21 CCU98423.1 - 3.5e-13 49.6 0.0 9.3e-13 48.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CCU98423.1 - 7.4e-09 35.1 0.0 9.1e-08 31.6 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 CCU98423.1 - 2.1e-07 30.2 0.0 1.6e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase_fungal PF17667.1 CCU98423.1 - 1e-05 24.5 0.8 5.2e-05 22.2 0.8 2.1 1 1 0 1 1 1 1 Fungal protein kinase NAD_binding_10 PF13460.6 CCU98423.1 - 4.2e-05 23.5 0.0 8.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Kdo PF06293.14 CCU98423.1 - 0.00037 19.9 0.0 0.00084 18.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCU98423.1 - 0.00061 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCU98423.1 - 0.0008 19.4 0.8 0.0029 17.6 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family GDP_Man_Dehyd PF16363.5 CCU98423.1 - 0.0012 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase PQQ_2 PF13360.6 CCU98423.1 - 0.013 15.1 0.1 0.21 11.1 0.0 2.7 2 1 1 3 3 3 0 PQQ-like domain NmrA PF05368.13 CCU98423.1 - 0.014 14.9 0.0 0.048 13.2 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family YrbL-PhoP_reg PF10707.9 CCU98423.1 - 0.039 13.5 0.3 0.077 12.5 0.0 1.6 2 0 0 2 2 1 0 PhoP regulatory network protein YrbL DUF4778 PF16008.5 CCU98423.1 - 0.065 13.3 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) PQQ PF01011.21 CCU98423.1 - 0.09 12.7 0.0 0.39 10.7 0.0 2.1 1 0 0 1 1 1 0 PQQ enzyme repeat Rrn6 PF10214.9 CCU98423.1 - 0.92 7.9 7.6 1.5 7.2 7.6 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor ArsA_ATPase PF02374.15 CCU98424.1 - 6.9e-108 360.4 0.0 7.9e-108 360.2 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CCU98424.1 - 7.6e-13 48.8 0.0 2.3e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CCU98424.1 - 6e-12 45.7 0.0 3.6e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CCU98424.1 - 4.1e-05 23.1 0.2 0.00018 21.1 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 CCU98424.1 - 4.6e-05 23.0 1.8 0.00031 20.3 0.6 2.5 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 CCU98424.1 - 6.3e-05 22.6 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 CCU98424.1 - 0.00024 20.8 0.0 0.0012 18.5 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PhoH PF02562.16 CCU98424.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 CCU98424.1 - 0.032 13.8 0.0 0.91 9.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain MipZ PF09140.11 CCU98424.1 - 0.1 11.8 0.1 1 8.6 0.1 2.2 2 1 0 2 2 2 0 ATPase MipZ AAA_24 PF13479.6 CCU98424.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 CCU98425.1 - 1.6e-10 41.2 0.0 2.1e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCU98425.1 - 6.8e-09 36.0 0.0 1.1e-08 35.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CCU98425.1 - 7.4e-07 29.2 0.0 1.1e-06 28.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCU98425.1 - 2.8e-05 24.0 0.0 5.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CCU98425.1 - 0.0068 16.5 0.6 0.017 15.2 0.6 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Atg14 PF10186.9 CCU98426.1 - 1.8e-09 37.2 10.4 1.8e-08 33.9 10.4 2.1 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Vitellogenin_N PF01347.22 CCU98426.1 - 0.005 15.3 0.6 0.0062 15.0 0.6 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region Cbl_N PF02262.16 CCU98426.1 - 0.035 14.1 2.5 0.58 10.2 0.2 2.2 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 DUF3618 PF12277.8 CCU98426.1 - 0.062 13.6 8.2 1.1 9.6 1.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3618) DUF883 PF05957.13 CCU98426.1 - 0.37 11.4 4.6 9.5 6.9 4.6 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YqjK PF13997.6 CCU98426.1 - 7.3 6.9 7.1 0.65 10.3 0.8 2.5 4 0 0 4 4 4 0 YqjK-like protein CDC45 PF02724.14 CCU98427.1 - 1.1e-219 730.9 0.0 1.3e-219 730.7 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 CCU98427.1 - 0.00077 19.7 1.9 0.0016 18.6 1.9 1.4 1 0 0 1 1 1 1 YL1 nuclear protein SAGA-Tad1 PF12767.7 CCU98427.1 - 0.029 14.1 0.1 0.051 13.3 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF5523 PF17661.1 CCU98427.1 - 0.19 11.4 2.7 0.34 10.6 2.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) SNF2_N PF00176.23 CCU98428.1 - 1.5e-73 247.6 0.6 2.8e-73 246.6 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCU98428.1 - 5.6e-24 84.6 0.6 1.6e-20 73.5 0.0 4.1 3 1 1 4 4 4 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 CCU98428.1 - 1.9e-19 69.5 0.1 5e-19 68.2 0.1 1.8 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 CCU98428.1 - 3.5e-19 68.9 7.4 3.5e-19 68.9 7.4 3.4 3 0 0 3 3 3 1 HSA SnAC PF14619.6 CCU98428.1 - 1e-12 48.5 0.4 1e-12 48.5 0.4 4.5 4 1 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 CCU98428.1 - 6.1e-10 39.4 1.1 1.6e-09 38.0 0.1 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CCU98428.1 - 0.00023 20.9 0.0 0.00023 20.9 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase TraD PF06412.11 CCU98428.1 - 0.03 14.1 0.5 0.03 14.1 0.5 2.8 4 0 0 4 4 4 0 Conjugal transfer protein TraD Usp PF00582.26 CCU98429.1 - 6.7e-21 75.3 0.0 9.3e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family DUF2294 PF10057.9 CCU98429.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) Ribosomal_L3 PF00297.22 CCU98430.1 - 6.3e-188 624.3 10.0 7.1e-188 624.1 10.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RRM_1 PF00076.22 CCU98431.1 - 4.4e-35 119.3 0.0 2.4e-18 65.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCU98431.1 - 3.8e-05 23.3 0.0 0.0059 16.2 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CCU98431.1 - 0.0018 18.3 0.0 0.91 9.6 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 RRM_7 PF16367.5 CCU98431.1 - 0.0042 17.2 0.0 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 CCU98431.1 - 0.074 12.9 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif Cas_Cas2CT1978 PF09707.10 CCU98431.1 - 0.075 13.1 0.0 5.7 7.1 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) PHM7_cyt PF14703.6 CCU98431.1 - 0.19 12.0 0.0 25 5.1 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Per1 PF04080.13 CCU98432.1 - 1.3e-100 336.4 4.6 2e-100 335.8 4.6 1.3 1 0 0 1 1 1 1 Per1-like family eIF3_subunit PF08597.10 CCU98433.1 - 1.7e-41 142.8 19.0 1.9e-41 142.6 19.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Troponin-I_N PF11636.8 CCU98433.1 - 0.35 10.8 7.2 1.9 8.5 0.4 2.8 2 0 0 2 2 2 0 Troponin I residues 1-32 Tub_N PF16322.5 CCU98433.1 - 0.41 11.0 10.9 0.25 11.7 8.2 1.8 2 0 0 2 2 2 0 Tubby N-terminal CDC45 PF02724.14 CCU98433.1 - 2.8 6.1 7.5 2.9 6.1 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein MGTL PF17059.5 CCU98433.1 - 3 7.8 5.6 4 7.4 0.6 2.4 2 0 0 2 2 2 0 MgtA leader peptide PBP1_TM PF14812.6 CCU98433.1 - 7.3 7.0 26.0 10 6.6 7.8 2.7 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRN3 PF05327.11 CCU98433.1 - 8.5 4.8 8.8 11 4.4 8.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 tRNA-synt_1 PF00133.22 CCU98434.1 - 4.4e-140 467.8 0.0 5.7e-140 467.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CCU98434.1 - 1.2e-18 67.0 0.0 1.4e-12 47.1 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CCU98434.1 - 1.5e-16 60.7 0.0 2.9e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CCU98434.1 - 0.026 13.9 0.0 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Bcr-Abl_Oligo PF09036.10 CCU98434.1 - 0.08 13.0 0.0 9.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain tRNA-synt_1_2 PF13603.6 CCU98434.1 - 0.16 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Pox_MCEL PF03291.16 CCU98435.1 - 2.5e-70 237.2 0.0 3.2e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CCU98435.1 - 1.5e-12 48.1 0.0 3e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCU98435.1 - 2.4e-08 34.6 0.0 6.3e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCU98435.1 - 2.8e-08 34.3 0.0 6.9e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCU98435.1 - 2.9e-08 33.7 0.0 4.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCU98435.1 - 8.8e-08 32.1 0.0 1.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CCU98435.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MTS PF05175.14 CCU98435.1 - 0.026 14.1 0.0 0.064 12.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Mak10 PF04112.13 CCU98436.1 - 3.1e-32 111.4 0.0 1.2e-31 109.5 0.0 1.8 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase PIG-U PF06728.13 CCU98437.1 - 1.3e-78 264.7 20.8 1.5e-78 264.5 20.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mo25 PF08569.11 CCU98438.1 - 1.2e-81 274.6 7.1 3.5e-80 269.8 7.1 2.3 1 1 0 1 1 1 1 Mo25-like V-ATPase_H_N PF03224.14 CCU98438.1 - 3.3e-05 23.3 2.8 6.1e-05 22.5 2.8 1.4 1 0 0 1 1 1 1 V-ATPase subunit H RNase_E_G PF10150.9 CCU98438.1 - 0.11 11.9 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family FtsX_ECD PF18075.1 CCU98438.1 - 0.13 12.9 0.0 0.39 11.4 0.0 1.9 1 1 0 1 1 1 0 FtsX extracellular domain ZYG-11_interact PF05884.12 CCU98438.1 - 0.17 11.3 0.3 0.25 10.7 0.0 1.4 2 0 0 2 2 2 0 Interactor of ZYG-11 Adaptin_N PF01602.20 CCU98439.1 - 5.6e-136 454.2 4.1 6.5e-136 453.9 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CCU98439.1 - 1.9e-15 57.1 0.0 3.7e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CCU98439.1 - 8.7e-07 29.1 6.9 0.00088 19.4 0.3 4.1 4 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CCU98439.1 - 0.00029 20.8 2.5 31 5.2 0.0 5.6 5 0 0 5 5 5 0 HEAT repeat CLASP_N PF12348.8 CCU98439.1 - 0.052 13.1 0.4 2.9 7.4 0.1 3.0 2 0 0 2 2 2 0 CLASP N terminal TIP120 PF08623.10 CCU98439.1 - 0.21 11.4 5.7 3.3 7.4 0.2 4.1 3 2 2 5 5 5 0 TATA-binding protein interacting (TIP20) V-ATPase_H_C PF11698.8 CCU98439.1 - 0.35 11.0 1.6 11 6.2 0.0 3.4 3 1 1 4 4 4 0 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 CCU98439.1 - 0.53 10.9 3.1 25 5.5 0.1 3.8 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region UPF1_Zn_bind PF09416.10 CCU98440.1 - 6.1e-66 221.1 2.1 8.9e-66 220.6 1.4 1.7 2 0 0 2 2 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 CCU98440.1 - 2.1e-58 197.2 0.0 5.3e-58 195.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CCU98440.1 - 3.5e-52 177.8 3.1 5.2e-29 101.8 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 CCU98440.1 - 4.5e-23 81.3 0.0 8.4e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 CCU98440.1 - 6.5e-16 58.6 0.0 2.4e-15 56.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCU98440.1 - 1e-11 45.3 0.1 2.7e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CCU98440.1 - 4.9e-06 26.7 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 CCU98440.1 - 5.1e-05 23.2 0.1 0.0002 21.2 0.1 2.1 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 CCU98440.1 - 6.1e-05 22.7 0.1 0.035 13.6 0.1 2.4 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 CCU98440.1 - 0.00036 20.4 0.0 1.6 8.4 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 CCU98440.1 - 0.0016 18.3 0.2 0.0035 17.1 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 CCU98440.1 - 0.0022 17.3 0.2 0.0022 17.3 0.2 3.8 4 1 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 CCU98440.1 - 0.0061 16.2 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_10 PF12846.7 CCU98440.1 - 0.0096 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain PhoH PF02562.16 CCU98440.1 - 0.011 15.3 0.1 0.089 12.2 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 CCU98440.1 - 0.012 14.9 0.0 0.51 9.7 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_5 PF07728.14 CCU98440.1 - 0.018 15.0 0.2 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCU98440.1 - 0.024 14.9 0.1 0.076 13.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 CCU98440.1 - 0.034 13.3 0.1 5.1 6.2 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_16 PF13191.6 CCU98440.1 - 0.08 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 CCU98440.1 - 0.16 11.3 0.0 0.45 9.9 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AMP-binding PF00501.28 CCU98441.1 - 5.4e-90 302.0 0.0 6.8e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCU98441.1 - 4.9e-13 49.8 0.2 2e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ysc84 PF04366.12 CCU98443.1 - 8.9e-35 119.2 0.2 1.3e-34 118.7 0.2 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CCU98443.1 - 3.1e-11 42.7 0.0 5.4e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CCU98443.1 - 4.8e-07 29.4 0.0 8.4e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CCU98443.1 - 1e-06 28.5 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF4592 PF15262.6 CCU98443.1 - 0.81 10.4 4.8 1.1 10.0 4.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4592) DUF1518 PF07469.12 CCU98443.1 - 4.4 7.8 10.6 0.14 12.6 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) Pkinase PF00069.25 CCU98444.1 - 3.2e-55 187.4 0.0 4.5e-38 131.1 0.0 3.3 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98444.1 - 2.2e-27 96.0 0.4 2e-17 63.4 0.0 3.5 4 1 0 4 4 4 2 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 CCU98444.1 - 2e-26 93.1 0.3 2.5e-24 86.2 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs RWD PF05773.22 CCU98444.1 - 2.5e-13 50.3 0.0 6.5e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 CCU98444.1 - 2.1e-11 43.7 0.0 4.6e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase FTA2 PF13095.6 CCU98444.1 - 0.00097 18.8 0.0 1.9 8.1 0.0 2.6 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CCU98444.1 - 0.0011 18.9 0.1 0.0011 18.9 0.1 4.3 5 1 1 6 6 6 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CCU98444.1 - 0.008 15.2 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CCU98444.1 - 0.036 13.4 0.0 0.12 11.7 0.0 1.9 2 1 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 CCU98444.1 - 2.4 6.9 5.7 0.23 10.2 0.2 1.9 2 0 0 2 2 2 0 Fungal protein kinase Ank_4 PF13637.6 CCU98445.1 - 3.2e-10 40.3 0.1 1.8e-09 38.0 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CCU98445.1 - 7.3e-08 32.5 0.1 3.4e-07 30.4 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCU98445.1 - 1.9e-06 28.3 0.0 4.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CCU98445.1 - 3.4e-05 24.1 0.0 9.2e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 CCU98445.1 - 0.0032 17.8 0.0 0.016 15.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Methyltransf_25 PF13649.6 CCU98445.1 - 0.14 12.9 0.0 0.36 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Nucleoporin_FG PF13634.6 CCU98446.1 - 6.5e-15 55.8 104.7 1.3e-08 35.5 31.9 4.2 1 1 3 4 4 4 3 Nucleoporin FG repeat region Helo_like_N PF17111.5 CCU98446.1 - 0.032 13.6 4.3 0.059 12.7 1.3 2.0 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins AvrPto PF11592.8 CCU98446.1 - 0.067 13.2 0.3 0.18 11.9 0.3 1.7 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto CRR7 PF12095.8 CCU98446.1 - 0.27 11.7 2.3 6.3 7.3 0.1 3.0 1 1 2 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 Uds1 PF15456.6 CCU98446.1 - 0.86 9.8 8.2 2.2 8.4 5.3 2.2 2 0 0 2 2 2 0 Up-regulated During Septation KxDL PF10241.9 CCU98446.1 - 4.4 7.6 9.4 1.4 9.2 1.4 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein ABC_tran PF00005.27 CCU98447.1 - 5e-29 101.6 0.0 7.7e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CCU98447.1 - 1.8e-13 50.8 4.4 2.3e-13 50.4 4.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CCU98447.1 - 0.00034 20.1 0.3 0.0032 16.9 0.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CCU98447.1 - 0.047 13.6 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 CCU98447.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CCU98447.1 - 0.34 10.7 1.1 0.77 9.6 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain OGG_N PF07934.12 CCU98448.1 - 1.4e-22 80.0 0.0 2.3e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CCU98448.1 - 1.6e-10 41.4 0.0 2.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CCU98448.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif GLE1 PF07817.13 CCU98449.1 - 5.1e-33 114.3 0.2 8.6e-33 113.6 0.2 1.3 1 0 0 1 1 1 1 GLE1-like protein AAA_11 PF13086.6 CCU98449.1 - 1.1 9.0 9.4 1.8 8.3 9.4 1.5 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 CCU98449.1 - 3.9 5.3 8.9 4.8 5.0 8.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRAPP PF04051.16 CCU98451.1 - 0.007 16.1 0.0 0.0097 15.6 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component TRAPP PF04051.16 CCU98452.1 - 1.5e-09 37.7 0.0 1.8e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Aldedh PF00171.22 CCU98453.1 - 4.2e-104 348.6 0.0 5e-104 348.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NOGCT PF08155.11 CCU98455.1 - 7.7e-29 99.5 3.4 2.5e-28 97.8 3.4 2.0 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 CCU98455.1 - 4.1e-28 96.9 0.1 8.7e-28 95.9 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOG1_N PF17835.1 CCU98455.1 - 2.4e-23 82.9 0.2 2.4e-23 82.9 0.2 2.3 2 0 0 2 2 2 1 NOG1 N-terminal helical domain MMR_HSR1 PF01926.23 CCU98455.1 - 3.9e-18 65.6 0.0 1.1e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCU98455.1 - 3.1e-09 36.6 0.0 5.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CCU98455.1 - 5.1e-05 23.4 2.7 0.21 11.6 0.0 3.5 2 1 1 3 3 3 2 Dynamin family Ras PF00071.22 CCU98455.1 - 0.0029 17.2 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 CCU98455.1 - 0.0045 16.9 0.2 0.62 10.0 0.0 3.0 2 1 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 CCU98455.1 - 0.0091 15.3 1.4 0.025 13.9 0.0 2.3 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 CCU98455.1 - 0.024 15.0 0.5 0.38 11.1 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 CCU98455.1 - 0.045 14.0 0.0 0.31 11.3 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sipho_Gp157 PF05565.11 CCU98455.1 - 0.098 12.7 10.0 0.3 11.1 10.0 1.8 1 0 0 1 1 1 0 Siphovirus Gp157 Gas_vesicle_C PF01304.17 CCU98455.1 - 3.7 7.6 8.2 12 5.9 8.2 1.9 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain SPT6_acidic PF14632.6 CCU98455.1 - 7.3 7.2 19.8 5.4 7.7 12.8 3.1 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Sugar_tr PF00083.24 CCU98456.1 - 4.3e-164 546.7 53.1 6.9e-86 288.9 22.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CCU98456.1 - 3.1e-29 102.0 73.2 7e-17 61.4 31.6 3.9 3 2 1 4 4 4 3 Major Facilitator Superfamily DUF5368 PF17336.2 CCU98456.1 - 0.0017 18.5 2.5 1 9.6 0.2 3.0 2 0 0 2 2 2 2 Family of unknown function (DUF5368) DUF4293 PF14126.6 CCU98456.1 - 0.45 10.8 10.8 3.5 7.9 0.5 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) ChaC PF04752.12 CCU98458.1 - 1.4e-30 106.7 0.0 2.5e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 ChaC-like protein DUF1749 PF08538.10 CCU98458.1 - 0.0019 17.3 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.7 CCU98459.1 - 0.0097 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CCU98459.1 - 0.055 12.4 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 CCU98459.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF1749 PF08538.10 CCU98459.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) CRAL_TRIO PF00650.20 CCU98460.1 - 1.5e-34 119.0 0.1 2.4e-34 118.4 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCU98460.1 - 1.8e-08 34.4 2.6 2e-08 34.3 0.3 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CCU98460.1 - 0.13 12.4 0.1 0.29 11.3 0.1 1.6 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain Aldedh PF00171.22 CCU98461.1 - 1e-149 499.0 0.7 1.3e-149 498.7 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CCU98461.1 - 0.094 12.1 0.0 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) RNase_H PF00075.24 CCU98462.1 - 0.0021 18.3 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 RNase H UPF0203 PF05254.12 CCU98463.1 - 0.016 15.4 1.0 0.028 14.7 1.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) CHCH PF06747.13 CCU98463.1 - 0.04 14.1 4.9 0.27 11.4 0.1 2.3 2 0 0 2 2 2 0 CHCH domain PH_14 PF17787.1 CCU98463.1 - 0.075 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 PH domain CX9C PF16860.5 CCU98463.1 - 0.14 12.2 2.8 6.4 6.9 0.6 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ChaC PF04752.12 CCU98464.1 - 8.3e-51 172.6 0.0 1.5e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 ChaC-like protein DnaJ PF00226.31 CCU98464.1 - 3e-24 84.9 1.6 1.3e-23 82.9 1.6 2.2 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 CCU98464.1 - 3.1e-09 36.9 2.5 3.1e-09 36.9 2.5 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCU98464.1 - 2.9e-08 33.8 1.3 2.9e-08 33.8 1.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CCU98464.1 - 0.0001 22.6 5.3 0.041 14.2 0.2 3.2 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CCU98464.1 - 0.0024 18.5 6.1 0.81 10.7 2.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCU98464.1 - 0.011 15.7 7.1 1.2 9.2 0.9 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Paired_CXXCH_1 PF09699.10 CCU98464.1 - 0.11 12.3 1.7 2.6 7.8 1.7 2.6 1 1 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-C2H2 PF00096.26 CCU98464.1 - 0.14 12.7 6.9 0.58 10.7 2.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type PhoD PF09423.10 CCU98465.1 - 0.00087 18.4 0.0 0.79 8.7 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Pectate_lyase_3 PF12708.7 CCU98466.1 - 3.8e-30 105.3 0.2 4.6e-19 69.1 0.1 2.3 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 CCU98466.1 - 0.03 14.0 0.1 0.091 12.5 0.0 1.8 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Cyt-b5 PF00173.28 CCU98467.1 - 8.8e-18 64.2 0.0 1.6e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arginase PF00491.21 CCU98468.1 - 8.7e-76 255.1 0.0 1.1e-75 254.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family AAA PF00004.29 CCU98469.1 - 8.6e-92 304.5 0.0 1.1e-46 158.6 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCU98469.1 - 4.1e-23 80.9 0.0 2.4e-11 43.3 0.1 2.8 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 CCU98469.1 - 3.9e-13 49.4 0.0 1.4e-05 24.9 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CCU98469.1 - 2.5e-11 44.0 0.0 0.00018 21.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CCU98469.1 - 3.3e-11 43.9 4.9 7e-05 23.3 0.1 4.8 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 CCU98469.1 - 7.1e-10 39.0 0.4 0.0031 17.5 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCU98469.1 - 1.9e-09 37.9 0.9 0.017 15.4 0.0 5.0 2 2 2 4 4 4 2 AAA domain AAA_33 PF13671.6 CCU98469.1 - 3.3e-09 37.0 0.0 0.0017 18.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CCU98469.1 - 1.1e-08 34.7 0.0 0.00043 19.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 CCU98469.1 - 2.3e-07 30.4 0.2 0.025 13.9 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CCU98469.1 - 6.9e-07 29.6 0.0 0.066 13.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 CCU98469.1 - 2.6e-06 27.8 0.0 0.04 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CCU98469.1 - 5.2e-06 26.5 0.0 0.017 15.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CCU98469.1 - 5.4e-06 26.3 0.0 0.031 14.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 CCU98469.1 - 1.3e-05 25.7 0.0 0.3 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 CCU98469.1 - 1.5e-05 24.8 0.0 0.063 13.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CCU98469.1 - 1.8e-05 25.3 0.0 0.031 14.8 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Cytidylate_kin2 PF13189.6 CCU98469.1 - 2.6e-05 24.4 0.0 0.0055 16.8 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Rad17 PF03215.15 CCU98469.1 - 3.1e-05 24.0 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 CCU98469.1 - 3.4e-05 23.5 0.0 0.35 10.4 0.0 2.8 2 2 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 CCU98469.1 - 4e-05 23.6 0.5 0.83 9.5 0.1 3.3 2 1 1 3 3 3 2 NACHT domain TsaE PF02367.17 CCU98469.1 - 0.00011 22.2 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 CCU98469.1 - 0.00013 22.4 0.3 0.29 11.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CCU98469.1 - 0.00033 20.3 8.6 1.1 8.9 0.0 4.9 3 2 2 5 5 5 2 AAA domain Sigma54_activ_2 PF14532.6 CCU98469.1 - 0.00043 20.4 0.0 1.3 9.1 0.0 2.9 3 0 0 3 3 2 2 Sigma-54 interaction domain ATPase PF06745.13 CCU98469.1 - 0.00045 19.6 0.1 1.4 8.2 0.0 3.2 3 0 0 3 3 3 1 KaiC AAA_11 PF13086.6 CCU98469.1 - 0.00053 19.8 0.0 0.68 9.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CCU98469.1 - 0.00075 19.3 0.0 0.71 9.6 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 CCU98469.1 - 0.00097 18.9 0.1 0.38 10.4 0.0 3.3 4 0 0 4 4 4 1 Sigma-54 interaction domain Trypan_PARP PF05887.11 CCU98469.1 - 0.0013 18.7 15.5 0.0028 17.6 15.5 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Parvo_NS1 PF01057.17 CCU98469.1 - 0.0014 17.8 0.1 1.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 CCU98469.1 - 0.0014 17.9 0.1 0.33 10.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.22 CCU98469.1 - 0.003 16.8 0.0 0.71 9.0 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain SKI PF01202.22 CCU98469.1 - 0.0031 17.7 0.1 3.2 7.9 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase DUF815 PF05673.13 CCU98469.1 - 0.004 16.3 0.0 0.012 14.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.16 CCU98469.1 - 0.0069 15.9 0.3 1.5 8.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AFG1_ATPase PF03969.16 CCU98469.1 - 0.0088 15.0 0.0 2.9 6.7 0.0 2.6 2 0 0 2 2 2 1 AFG1-like ATPase TniB PF05621.11 CCU98469.1 - 0.01 15.3 0.0 19 4.6 0.0 3.4 3 0 0 3 3 3 0 Bacterial TniB protein AAA_24 PF13479.6 CCU98469.1 - 0.015 15.0 0.0 0.82 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CCU98469.1 - 0.023 14.3 0.0 5.2 6.7 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 CCU98469.1 - 0.053 13.4 0.1 1.2 9.0 0.0 2.8 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea ResIII PF04851.15 CCU98469.1 - 0.075 13.0 0.0 19 5.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Vps4_C PF09336.10 CCU98469.1 - 0.096 12.7 0.1 9.6 6.3 0.0 3.2 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain Hydin_ADK PF17213.3 CCU98469.1 - 0.13 12.5 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain PduV-EutP PF10662.9 CCU98469.1 - 0.17 11.6 0.0 7.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 CCU98469.1 - 0.27 11.5 1.8 14 6.0 0.0 2.9 2 1 0 3 3 3 0 AAA domain AAA_30 PF13604.6 CCU98469.1 - 0.76 9.5 3.6 17 5.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain P21-Arc PF04062.14 CCU98470.1 - 1.8e-68 230.0 0.0 2.3e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit PCI PF01399.27 CCU98471.1 - 7.8e-13 48.9 0.1 3.8e-12 46.6 0.0 2.2 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 CCU98471.1 - 4.9e-10 38.9 2.1 4.9e-10 38.9 2.1 2.1 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix HTH_20 PF12840.7 CCU98471.1 - 0.078 13.0 0.8 0.46 10.6 0.3 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CCU98471.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Sybindin PF04099.12 CCU98472.1 - 5.6e-37 126.8 0.0 6.2e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CCU98472.1 - 8e-07 29.2 0.0 8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PTH2 PF01981.16 CCU98473.1 - 0.00061 20.1 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 2-Hacid_dh_C PF02826.19 CCU98474.1 - 4.2e-48 163.1 0.0 6.5e-48 162.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCU98474.1 - 3e-14 52.8 0.0 3.9e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CCU98474.1 - 0.015 15.5 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 CCU98474.1 - 0.16 11.6 0.3 0.31 10.7 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Gp_dh_N PF00044.24 CCU98474.1 - 0.18 12.1 0.0 0.66 10.4 0.0 2.0 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NIF PF03031.18 CCU98475.1 - 2.3e-34 118.4 0.0 3.9e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Methyltransf_16 PF10294.9 CCU98476.1 - 9.4e-12 45.0 0.0 1.7e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 CCU98476.1 - 0.0031 18.2 0.0 0.0056 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCU98476.1 - 0.0041 17.8 0.1 0.012 16.3 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCU98476.1 - 0.036 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain GidB PF02527.15 CCU98476.1 - 0.083 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF43 PF01861.16 CCU98476.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain MRP-S28 PF10213.9 CCU98477.1 - 3e-24 85.9 0.0 8.1e-24 84.5 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein RRP7 PF12923.7 CCU98478.1 - 1e-21 77.3 5.6 3.2e-21 75.7 5.6 1.8 1 1 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 CCU98478.1 - 1.9e-14 53.8 0.0 5.1e-14 52.4 0.0 1.7 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 CCU98478.1 - 0.00019 21.2 0.0 0.00081 19.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MCM PF00493.23 CCU98479.1 - 3.9e-102 340.1 0.2 6e-102 339.5 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCU98479.1 - 1.9e-39 134.4 0.3 3.5e-39 133.5 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCU98479.1 - 6.8e-27 93.7 0.3 1.7e-26 92.5 0.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 CCU98479.1 - 2.5e-25 88.8 1.3 5.3e-25 87.7 1.3 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 CCU98479.1 - 1.6e-20 73.6 0.2 3.9e-20 72.4 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCU98479.1 - 1.2e-07 31.4 0.0 1e-06 28.3 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CCU98479.1 - 0.0011 18.8 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCU98479.1 - 0.0016 18.2 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 CCU98479.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tir_receptor_M PF03549.14 CCU98479.1 - 0.072 13.4 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain Proteasome PF00227.26 CCU98481.1 - 1.6e-46 158.2 0.0 2.8e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M28 PF04389.17 CCU98481.1 - 4.7e-23 81.9 0.0 8e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CCU98481.1 - 7.2e-14 51.6 0.3 2.6e-13 49.8 0.3 2.0 1 0 0 1 1 1 1 PA domain Proteasome_A_N PF10584.9 CCU98481.1 - 0.00071 19.2 0.2 0.0015 18.2 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature WD40 PF00400.32 CCU98482.1 - 1.4e-36 123.9 12.6 1.7e-09 38.2 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU98482.1 - 1.4e-05 25.3 0.4 5.3 7.4 0.1 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCU98482.1 - 0.00031 19.5 0.4 1.7 7.2 0.0 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 tRNA-synt_2 PF00152.20 CCU98484.1 - 2.7e-72 243.5 0.0 4e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCU98484.1 - 6.9e-11 42.0 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain T2SSE_N PF05157.15 CCU98484.1 - 0.042 14.1 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain cNMP_binding PF00027.29 CCU98485.1 - 1.5e-38 130.7 0.0 5.3e-19 68.1 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Mt_ATP-synt_D PF05873.12 CCU98485.1 - 5.3e-16 58.8 1.1 8.7e-16 58.1 1.1 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Prominin PF05478.11 CCU98485.1 - 0.033 12.2 0.4 0.043 11.8 0.4 1.1 1 0 0 1 1 1 0 Prominin AcetDehyd-dimer PF09290.11 CCU98485.1 - 0.05 13.8 0.8 4.3 7.5 0.0 2.6 3 0 0 3 3 3 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation She9_MDM33 PF05546.11 CCU98485.1 - 0.1 12.4 0.8 0.58 9.9 0.1 2.1 1 1 1 2 2 2 0 She9 / Mdm33 family TMPIT PF07851.13 CCU98485.1 - 0.13 11.5 0.6 0.2 10.9 0.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Ribosomal_S25 PF03297.15 CCU98486.1 - 5.1e-38 129.3 0.3 6.1e-38 129.1 0.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MerR_1 PF13411.6 CCU98486.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 MerR HTH family regulatory protein DDRGK PF09756.9 CCU98486.1 - 0.031 13.9 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 DDRGK domain EF-hand_6 PF13405.6 CCU98487.1 - 6e-14 50.7 0.3 8e-05 22.3 0.1 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CCU98487.1 - 8.8e-14 49.9 0.8 7.3e-05 22.0 0.0 4.1 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 CCU98487.1 - 7.8e-13 48.7 0.0 3e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CCU98487.1 - 1.2e-08 35.1 0.0 0.0064 16.8 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CCU98487.1 - 8.4e-06 25.5 0.2 0.0054 16.6 0.0 3.8 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 CCU98487.1 - 6e-05 22.3 0.5 0.58 9.8 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_14 PF17959.1 CCU98487.1 - 0.17 12.3 0.0 1.3 9.4 0.0 2.1 2 1 0 2 2 2 0 EF-hand domain CENP-Q PF13094.6 CCU98488.1 - 0.0023 18.1 3.7 0.021 15.0 2.9 2.1 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit IMD PF08397.11 CCU98488.1 - 0.0027 17.1 2.4 0.0039 16.6 2.4 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain Cast PF10174.9 CCU98488.1 - 0.013 13.8 2.9 0.018 13.3 2.9 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone IL28A PF15177.6 CCU98488.1 - 0.016 15.1 0.3 0.03 14.2 0.3 1.4 1 0 0 1 1 1 0 Interleukin-28A Gon7 PF08738.10 CCU98488.1 - 0.027 14.5 0.9 0.054 13.6 0.9 1.5 1 0 0 1 1 1 0 Gon7 family OmpH PF03938.14 CCU98488.1 - 0.061 13.7 3.5 0.058 13.7 1.5 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HrpB7 PF09486.10 CCU98488.1 - 0.075 13.4 4.5 0.15 12.5 3.7 1.9 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) TPR_MLP1_2 PF07926.12 CCU98488.1 - 0.53 10.4 10.5 0.086 12.9 5.6 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein AMMECR1 PF01871.17 CCU98489.1 - 1.1e-38 132.5 0.0 1.4e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Forkhead PF00250.18 CCU98491.1 - 2.3e-19 69.4 0.1 3.5e-19 68.8 0.1 1.3 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CCU98491.1 - 0.00016 21.9 0.0 0.00035 20.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain Gag_p10 PF02337.17 CCU98491.1 - 0.21 11.6 0.1 0.4 10.6 0.1 1.4 1 0 0 1 1 1 0 Retroviral GAG p10 protein TMEM208_SND2 PF05620.11 CCU98492.1 - 2e-43 148.1 0.6 3.2e-43 147.4 0.6 1.3 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 HXXEE PF13787.6 CCU98492.1 - 0.98 10.2 10.0 14 6.5 10.0 2.1 1 1 0 1 1 1 0 Protein of unknown function with HXXEE motif SNF5 PF04855.12 CCU98494.1 - 1e-56 192.4 0.0 2.2e-56 191.3 0.0 1.5 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 AT_hook PF02178.19 CCU98494.1 - 0.064 13.2 5.5 0.2 11.6 5.5 1.9 1 0 0 1 1 1 0 AT hook motif RRM_1 PF00076.22 CCU98495.1 - 8.9e-28 95.9 0.0 8.1e-17 60.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 CCU98495.1 - 3.4e-05 23.5 0.9 0.00011 21.8 0.9 1.8 1 0 0 1 1 1 1 Ribonuclease B OB domain Limkain-b1 PF11608.8 CCU98495.1 - 0.006 16.6 0.1 4.7 7.3 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 Flavokinase PF01687.17 CCU98497.1 - 4.8e-34 117.0 0.0 5.9e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Thr_synth_N PF14821.6 CCU98498.1 - 7.2e-24 83.8 0.0 3.7e-23 81.5 0.0 2.2 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 CCU98498.1 - 6.3e-19 68.5 0.3 1.5e-18 67.2 0.3 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WD40 PF00400.32 CCU98499.1 - 1.7e-14 54.0 7.9 0.0012 19.7 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU98499.1 - 2e-11 44.0 0.0 0.00032 20.9 0.0 5.7 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CCU98499.1 - 0.013 16.0 8.3 0.25 11.9 0.1 4.8 5 0 0 5 5 5 0 PQQ-like domain PQQ PF01011.21 CCU98499.1 - 0.069 13.1 0.2 0.52 10.3 0.1 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat DUF2415 PF10313.9 CCU98499.1 - 0.086 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) PfkB PF00294.24 CCU98500.1 - 9.1e-40 136.8 0.1 1.1e-39 136.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase B12-binding PF02310.19 CCU98500.1 - 0.066 13.3 0.1 4.5 7.3 0.1 2.5 1 1 1 2 2 2 0 B12 binding domain RNA_Me_trans PF04252.13 CCU98501.1 - 1.4e-53 181.5 0.0 3.5e-53 180.2 0.0 1.6 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase SNARE_assoc PF09335.11 CCU98502.1 - 6.3e-12 46.0 7.5 1.5e-11 44.8 7.5 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein Imm5 PF14423.6 CCU98502.1 - 0.015 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Immunity protein Imm5 Sod_Fe_C PF02777.18 CCU98503.1 - 9.6e-09 35.3 0.0 1.6e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CCU98503.1 - 0.014 15.9 0.0 0.02 15.4 0.0 1.2 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Ndc1_Nup PF09531.10 CCU98504.1 - 1.6e-35 122.9 10.1 6.4e-25 87.9 7.6 2.1 2 0 0 2 2 2 2 Nucleoporin protein Ndc1-Nup MCM PF00493.23 CCU98505.1 - 9.9e-99 329.0 0.0 1.5e-98 328.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCU98505.1 - 3.7e-29 101.1 0.1 6.9e-29 100.3 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCU98505.1 - 1.4e-21 76.7 1.0 3.8e-21 75.3 1.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCU98505.1 - 3.9e-16 59.5 0.0 1.1e-15 58.0 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCU98505.1 - 4.7e-07 29.4 0.1 5.1e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCU98505.1 - 8.1e-07 29.1 0.0 2.9e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCU98505.1 - 0.0046 17.4 3.2 1.5 9.2 0.7 3.7 2 1 0 2 2 2 2 AAA ATPase domain Mg_chelatase_C PF13335.6 CCU98505.1 - 0.0052 17.4 3.3 0.016 15.8 1.7 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 CCU98505.1 - 0.0067 16.3 0.0 0.031 14.1 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 CCU98505.1 - 0.0099 15.7 0.8 0.047 13.5 0.1 2.6 2 0 0 2 2 2 1 AAA lid domain LIM PF00412.22 CCU98507.1 - 3.8e-24 84.7 38.2 8.9e-14 51.5 6.8 4.7 4 1 0 4 4 4 3 LIM domain DZR PF12773.7 CCU98507.1 - 0.082 12.9 26.6 0.7 10.0 5.9 4.4 2 1 3 5 5 5 0 Double zinc ribbon zf-ribbon_3 PF13248.6 CCU98507.1 - 0.11 12.0 6.2 5.7 6.5 0.5 3.8 3 0 0 3 3 3 0 zinc-ribbon domain Cript PF10235.9 CCU98507.1 - 0.97 10.0 3.8 52 4.5 0.0 3.3 2 1 1 3 3 3 0 Microtubule-associated protein CRIPT JAB PF01398.21 CCU98508.1 - 4.8e-16 58.8 0.0 7e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CCU98508.1 - 2.8e-06 27.1 0.4 7.3e-06 25.7 0.4 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.11 CCU98508.1 - 0.068 13.4 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 USP8 dimerisation domain GCP_N_terminal PF17681.1 CCU98509.1 - 4.6e-80 269.5 0.1 1.9e-78 264.2 0.0 2.4 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CCU98509.1 - 1.1e-69 235.3 5.7 1.1e-69 235.3 5.7 1.9 2 1 1 3 3 3 1 Gamma tubulin complex component C-terminal BatA PF07584.11 CCU98509.1 - 0.064 13.6 2.4 0.12 12.8 0.9 2.2 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal MoaF PF10703.9 CCU98509.1 - 0.092 12.7 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 MoaF N-terminal domain ADH_N PF08240.12 CCU98510.1 - 4.8e-27 94.0 0.2 8.8e-27 93.1 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCU98510.1 - 5.1e-17 62.1 0.2 7.7e-17 61.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CCU98510.1 - 9.9e-08 31.7 0.9 1.7e-05 24.4 0.9 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CCU98510.1 - 0.00055 21.0 0.2 0.0013 19.8 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 CCU98510.1 - 0.021 14.1 0.1 0.042 13.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CCU98510.1 - 0.027 13.8 0.1 0.049 12.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CCU98510.1 - 0.098 13.2 0.1 0.26 11.9 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CCU98510.1 - 0.21 10.2 0.2 0.32 9.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Ras PF00071.22 CCU98511.1 - 8.1e-34 116.6 0.3 1e-33 116.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCU98511.1 - 3e-13 50.1 0.0 4.4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU98511.1 - 0.00017 21.1 0.0 0.00021 20.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCU98511.1 - 0.0037 16.8 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CCU98511.1 - 0.017 15.2 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Clat_adaptor_s PF01217.20 CCU98512.1 - 1.6e-14 54.0 0.0 6.1e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 CCU98512.1 - 0.0034 17.4 0.0 0.0049 16.9 0.0 1.2 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 RasGAP_C PF03836.15 CCU98513.1 - 1.6e-38 131.9 0.1 1.6e-38 131.9 0.1 2.9 2 1 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.19 CCU98513.1 - 4.9e-23 81.9 0.0 1.5e-22 80.3 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 CCU98513.1 - 1.2e-15 55.7 24.1 0.095 12.5 0.0 9.4 9 0 0 9 9 9 7 IQ calmodulin-binding motif CH PF00307.31 CCU98513.1 - 2.8e-15 56.5 0.0 6.6e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain Abhydrolase_3 PF07859.13 CCU98515.1 - 1.8e-24 86.8 0.2 1.1e-23 84.3 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CCU98515.1 - 2.6e-16 59.5 0.0 6.2e-14 51.7 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase COesterase PF00135.28 CCU98515.1 - 0.032 13.1 0.1 1.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Ytp1 PF10355.9 CCU98516.1 - 7.1e-104 346.9 3.7 1e-103 346.4 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CCU98516.1 - 6.5e-07 29.1 0.1 6.5e-07 29.1 0.1 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Aminotran_1_2 PF00155.21 CCU98517.1 - 6.8e-75 252.5 0.0 8.7e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CCU98517.1 - 5.8e-07 28.8 0.1 1.4e-06 27.6 0.1 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CCU98517.1 - 8.5e-05 21.2 0.0 0.00023 19.8 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CCU98517.1 - 0.016 14.6 0.3 0.031 13.6 0.3 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CCU98517.1 - 0.057 12.7 0.3 0.17 11.2 0.3 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase Ribosomal_S14 PF00253.21 CCU98518.1 - 2.2e-20 72.1 0.2 3.7e-20 71.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_L19 PF01245.20 CCU98519.1 - 1.1e-16 60.7 0.5 2.7e-16 59.5 0.5 1.6 1 1 0 1 1 1 1 Ribosomal protein L19 Not3 PF04065.15 CCU98520.1 - 3.1e-86 288.6 18.9 5.3e-86 287.8 18.9 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CCU98520.1 - 4.1e-45 153.1 9.4 1.2e-44 151.6 9.4 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 CCU98520.1 - 0.0043 16.9 2.8 0.011 15.5 2.8 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.6 CCU98520.1 - 0.14 12.6 5.2 0.59 10.5 0.9 2.7 3 0 0 3 3 3 0 Syntaxin-like protein Exonuc_VII_S PF02609.16 CCU98520.1 - 2.4 8.3 10.0 8.7 6.5 0.3 3.9 4 0 0 4 4 4 0 Exonuclease VII small subunit DUF4407 PF14362.6 CCU98520.1 - 4.2 6.6 8.3 0.98 8.7 4.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SART-1 PF03343.13 CCU98523.1 - 8e-120 401.3 27.8 3.2e-118 396.0 27.8 2.0 1 1 0 1 1 1 1 SART-1 family Pkinase PF00069.25 CCU98524.1 - 7.2e-67 225.5 0.0 9.2e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98524.1 - 1.3e-25 90.2 0.0 3.3e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCU98524.1 - 2.2e-06 27.2 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CCU98524.1 - 0.00021 20.2 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CCU98524.1 - 0.034 13.5 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CCU98525.1 - 2.8e-58 197.4 0.0 7.9e-58 195.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98525.1 - 5.7e-42 143.8 0.0 3.2e-41 141.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 CCU98525.1 - 1.1e-32 113.5 0.0 2.9e-32 112.0 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_fungal PF17667.1 CCU98525.1 - 0.0017 17.2 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CCU98525.1 - 0.052 12.9 0.0 2.2 7.5 0.0 2.4 3 0 0 3 3 3 0 Kinase-like APH PF01636.23 CCU98525.1 - 0.096 12.6 0.2 0.096 12.6 0.2 2.6 3 1 0 3 3 3 0 Phosphotransferase enzyme family Sedlin_N PF04628.13 CCU98526.1 - 9.3e-08 32.3 0.0 3.8e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Rho_GDI PF02115.17 CCU98527.1 - 1.4e-51 175.0 0.0 2e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Complex1_LYR PF05347.15 CCU98527.1 - 4.2e-08 33.1 3.0 8.2e-08 32.2 3.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF1640 PF07798.11 CCU98528.1 - 6.3e-59 199.0 1.8 8.1e-59 198.6 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Phage_Mu_Gam PF07352.12 CCU98528.1 - 0.0044 16.9 0.6 0.0078 16.1 0.6 1.4 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein OmpH PF03938.14 CCU98528.1 - 0.017 15.4 3.9 0.023 15.0 3.4 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Prominin PF05478.11 CCU98528.1 - 0.061 11.3 1.0 0.078 10.9 1.0 1.1 1 0 0 1 1 1 0 Prominin SF-assemblin PF06705.11 CCU98528.1 - 0.12 11.7 6.0 0.19 11.0 6.0 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin Baculo_PEP_C PF04513.12 CCU98528.1 - 0.17 11.9 6.8 0.54 10.3 6.8 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5344 PF17279.2 CCU98528.1 - 0.2 12.3 3.2 0.46 11.1 2.8 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5344) zf-ZPR1 PF03367.13 CCU98528.1 - 0.27 11.1 1.3 0.45 10.4 1.3 1.2 1 0 0 1 1 1 0 ZPR1 zinc-finger domain GCN5L1 PF06320.13 CCU98528.1 - 0.28 11.3 4.3 13 6.0 1.3 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Apolipoprotein PF01442.18 CCU98528.1 - 0.29 11.0 9.9 0.73 9.7 9.9 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Fzo_mitofusin PF04799.13 CCU98528.1 - 0.46 10.0 1.7 0.87 9.1 1.7 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF4795 PF16043.5 CCU98528.1 - 1.2 8.7 6.8 1.9 8.1 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) GTP_EFTU PF00009.27 CCU98529.1 - 7e-44 149.7 0.0 1e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCU98529.1 - 1.9e-34 118.3 0.2 7.4e-34 116.4 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCU98529.1 - 6.7e-09 36.0 0.6 2.3e-08 34.3 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCU98529.1 - 0.00054 20.0 0.0 0.0024 17.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase CDC27 PF09507.10 CCU98529.1 - 0.81 9.0 14.0 1.2 8.4 14.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAM2 PF07145.15 CCU98529.1 - 4.6 7.2 5.9 15 5.5 2.0 2.8 1 1 1 2 2 2 0 Ataxin-2 C-terminal region DAD PF02109.16 CCU98530.1 - 3.8e-40 136.6 1.6 4.8e-40 136.3 1.6 1.1 1 0 0 1 1 1 1 DAD family DUF1097 PF06496.11 CCU98530.1 - 0.016 15.4 2.8 0.024 14.7 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) DUF1768 PF08719.11 CCU98531.1 - 7.3e-21 75.1 0.0 1e-20 74.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Ribosomal_S7e PF01251.18 CCU98532.1 - 1.6e-80 269.2 1.5 1.8e-80 269.1 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e FAD_binding_1 PF00667.20 CCU98533.1 - 1.9e-49 168.2 0.0 3.2e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CCU98533.1 - 9e-07 29.5 0.0 2.4e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR_N PF01855.19 CCU98533.1 - 1.3e-05 25.1 1.5 2.7e-05 24.0 1.5 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 CCU98533.1 - 0.0037 17.5 0.0 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II POR PF01558.18 CCU98533.1 - 0.0084 16.2 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF3818 PF12825.7 CCU98534.1 - 6.9e-72 242.3 0.0 8.9e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CCU98534.1 - 6.3e-07 29.5 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 PX-associated S-AdoMet_synt_C PF02773.16 CCU98535.1 - 1.7e-68 228.9 0.7 6.2e-68 227.1 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 CCU98535.1 - 1.1e-45 154.3 0.9 1.7e-45 153.7 0.2 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 CCU98535.1 - 1.3e-44 151.3 0.0 2.5e-44 150.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 CCU98535.1 - 0.0089 14.9 0.2 0.094 11.5 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase (AdoMet synthetase) Lactamase_B_3 PF13483.6 CCU98535.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Exo70 PF03081.15 CCU98535.1 - 0.25 10.3 0.1 0.39 9.7 0.1 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit S4 PF01479.25 CCU98536.1 - 1.2e-11 44.1 0.0 2.1e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 CCU98536.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 S4 domain PTR2 PF00854.21 CCU98537.1 - 2.1e-70 237.6 13.4 2.6e-70 237.3 13.4 1.1 1 0 0 1 1 1 1 POT family MTP18 PF10558.9 CCU98537.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Glyco_hydro_cc PF11790.8 CCU98538.1 - 6.2e-59 199.4 11.0 7.1e-59 199.3 11.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_2_C PF02836.17 CCU98538.1 - 9.7e-05 21.6 0.9 0.00014 21.1 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_53 PF07745.13 CCU98538.1 - 0.04 12.9 3.8 0.092 11.7 3.8 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 53 WLM PF08325.10 CCU98539.1 - 3.6e-21 76.1 0.0 6e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.23 CCU98539.1 - 0.0021 17.7 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 CCU98539.1 - 0.033 14.1 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 CCU98539.1 - 0.074 13.5 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Adap_comp_sub PF00928.21 CCU98540.1 - 5.4e-36 124.3 0.0 7.4e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CCU98540.1 - 0.031 14.2 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain zf-Tim10_DDP PF02953.15 CCU98543.1 - 4.1e-20 71.2 1.6 4.1e-20 71.2 1.6 1.8 1 1 1 2 2 2 1 Tim10/DDP family zinc finger DUF1178 PF06676.11 CCU98543.1 - 0.016 15.6 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Phasin_2 PF09361.10 CCU98543.1 - 0.018 15.3 0.0 0.094 13.0 0.0 1.9 1 1 1 2 2 2 0 Phasin protein NdhS PF11623.8 CCU98543.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H dehydrogenase subunit S eIF-6 PF01912.18 CCU98544.1 - 3e-82 274.8 0.2 4.8e-82 274.1 0.1 1.4 2 0 0 2 2 2 1 eIF-6 family Sec7 PF01369.20 CCU98545.1 - 1.2e-71 240.2 0.2 2.8e-71 239.0 0.2 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CCU98545.1 - 5.3e-43 146.7 3.5 5.3e-43 146.7 3.5 2.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CCU98545.1 - 2e-29 101.3 5.8 3.7e-28 97.2 0.0 4.8 5 1 1 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 CCU98545.1 - 1.7e-21 76.7 0.5 1.7e-21 76.7 0.5 2.6 2 1 1 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 CCU98545.1 - 0.00021 19.6 0.3 0.003 15.8 0.0 2.6 3 0 0 3 3 3 1 C-terminal region of Mon2 protein Methyltransf_8 PF05148.15 CCU98546.1 - 3.9e-49 167.5 0.0 9.5e-24 84.5 0.0 3.0 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_25 PF13649.6 CCU98546.1 - 0.0015 19.2 0.0 0.0053 17.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCU98546.1 - 0.0024 18.5 0.1 0.017 15.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCU98546.1 - 0.0097 15.8 0.0 0.038 13.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMV_1a PF12467.8 CCU98546.1 - 6.8 7.0 6.0 1.6 9.0 0.8 2.1 1 1 1 2 2 2 0 Cucumber mosaic virus 1a protein family UPF0113_N PF17833.1 CCU98547.1 - 7.1e-30 103.4 0.0 1.1e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CCU98547.1 - 2.5e-24 85.3 0.0 3.7e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 CCU98547.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain DUF1825 PF08855.10 CCU98547.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) Utp14 PF04615.13 CCU98548.1 - 1e-128 431.1 90.7 1.4e-128 430.6 56.5 3.0 2 1 0 2 2 2 1 Utp14 protein RRP36 PF06102.12 CCU98548.1 - 5.9e-42 143.5 19.8 5.9e-42 143.5 19.8 4.3 3 1 1 4 4 4 1 rRNA biogenesis protein RRP36 NifU_N PF01592.16 CCU98550.1 - 4.3e-54 182.1 0.1 6.7e-54 181.5 0.1 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain adh_short_C2 PF13561.6 CCU98551.1 - 3.4e-60 203.5 0.6 4.4e-60 203.2 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CCU98551.1 - 1.1e-45 155.5 3.0 1.5e-45 155.1 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CCU98551.1 - 2.9e-17 63.2 0.5 4.8e-17 62.4 0.5 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CCU98551.1 - 0.00017 21.1 0.2 0.00024 20.6 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CCU98551.1 - 0.0014 18.1 0.1 0.0021 17.5 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 CCU98551.1 - 0.0022 17.9 0.5 0.041 13.8 0.5 2.4 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 CCU98551.1 - 0.0028 17.6 0.3 0.0036 17.2 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 CCU98551.1 - 0.0037 17.8 0.3 2.3 8.8 0.2 3.3 3 1 1 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.25 CCU98551.1 - 0.012 15.1 1.3 0.022 14.2 1.3 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Sacchrp_dh_NADP PF03435.18 CCU98551.1 - 0.014 15.7 0.6 0.029 14.6 0.6 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain YjeF_N PF03853.15 CCU98551.1 - 0.045 13.7 0.6 0.099 12.5 0.4 1.5 1 1 0 1 1 1 0 YjeF-related protein N-terminus TPP_enzyme_C PF02775.21 CCU98551.1 - 0.071 12.9 0.7 0.21 11.3 0.7 1.9 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF2280 PF10045.9 CCU98551.1 - 0.13 12.5 0.2 3.9 7.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) Ribosomal_L11_N PF03946.14 CCU98552.1 - 5.4e-25 87.0 1.6 8.2e-25 86.4 0.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CCU98552.1 - 0.00035 21.0 0.8 0.078 13.5 0.2 2.4 1 1 1 2 2 2 2 Ribosomal protein L11, RNA binding domain NUC153 PF08159.12 CCU98553.1 - 4.3e-13 48.8 0.3 9e-13 47.8 0.3 1.6 1 0 0 1 1 1 1 NUC153 domain PEX-2N PF09263.10 CCU98553.1 - 0.03 14.6 0.2 3.3 8.1 0.1 2.4 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal Proteasome PF00227.26 CCU98554.1 - 2e-58 197.0 0.0 3.2e-58 196.4 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 CCU98554.1 - 1.9e-09 37.0 0.0 7.3e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature HAD PF12710.7 CCU98555.1 - 1.9e-20 74.1 0.0 2.9e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 CCU98555.1 - 2.6e-06 27.1 0.1 2.6e-05 23.9 0.0 2.2 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 CCU98555.1 - 0.00056 20.3 0.4 0.027 14.7 0.1 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 CCU98555.1 - 0.058 12.8 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Putative Phosphatase Aldedh PF00171.22 CCU98556.1 - 1.5e-76 257.8 0.0 1.9e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CRAL_TRIO_2 PF13716.6 CCU98556.1 - 0.0045 17.1 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Fic PF02661.18 CCU98556.1 - 0.046 14.6 0.0 0.11 13.4 0.0 1.7 1 0 0 1 1 1 0 Fic/DOC family AAA_2 PF07724.14 CCU98557.1 - 7.1e-54 182.5 0.0 4.8e-50 170.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CCU98557.1 - 1.1e-31 108.8 1.3 1.1e-31 108.8 1.3 3.6 3 1 0 3 3 3 1 AAA lid domain AAA PF00004.29 CCU98557.1 - 6.6e-27 94.5 0.1 1.3e-14 54.7 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CCU98557.1 - 2.3e-21 75.6 0.2 1.6e-20 72.9 0.0 2.7 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CCU98557.1 - 4.6e-15 55.8 0.0 4.1e-09 36.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 CCU98557.1 - 6.7e-13 48.5 4.0 7e-06 26.1 0.1 3.8 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 CCU98557.1 - 1.5e-10 41.7 11.9 2.6e-06 27.9 0.0 5.5 5 2 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 CCU98557.1 - 6.9e-08 32.8 1.6 0.028 14.7 0.0 5.0 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 CCU98557.1 - 2e-07 30.9 0.0 3.1e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 CCU98557.1 - 4.1e-07 29.6 0.0 0.00077 18.9 0.0 3.7 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 CCU98557.1 - 6.3e-06 25.8 0.0 0.05 13.1 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 CCU98557.1 - 3.4e-05 23.7 0.0 0.1 12.3 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 CCU98557.1 - 5.1e-05 23.5 3.9 0.14 12.3 0.0 3.9 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 CCU98557.1 - 7.8e-05 23.0 0.0 0.36 11.2 0.0 3.4 4 0 0 4 4 3 1 RNA helicase Mg_chelatase PF01078.21 CCU98557.1 - 0.00016 21.1 0.0 0.19 11.1 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CCU98557.1 - 0.00029 20.6 0.0 0.39 10.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CCU98557.1 - 0.00035 20.3 0.1 0.56 9.9 0.0 3.5 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 CCU98557.1 - 0.0012 19.2 0.0 0.12 12.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 CCU98557.1 - 0.0013 18.1 0.0 0.59 9.4 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 CCU98557.1 - 0.0016 18.7 1.4 0.46 10.7 0.0 3.5 3 1 1 4 4 2 1 AAA domain AAA_18 PF13238.6 CCU98557.1 - 0.0022 18.5 0.1 3.3 8.3 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CCU98557.1 - 0.0031 17.5 0.0 6.1 6.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain Torsin PF06309.11 CCU98557.1 - 0.0036 17.4 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 1 1 Torsin RsgA_GTPase PF03193.16 CCU98557.1 - 0.0053 16.7 0.1 2.1 8.2 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase TsaE PF02367.17 CCU98557.1 - 0.0059 16.6 0.0 2.6 8.0 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 CCU98557.1 - 0.01 15.9 0.0 0.9 9.5 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF815 PF05673.13 CCU98557.1 - 0.013 14.7 0.0 0.54 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 CCU98557.1 - 0.016 15.0 5.4 2 8.1 0.1 4.1 4 2 0 5 5 4 0 AAA domain Roc PF08477.13 CCU98557.1 - 0.025 14.8 0.0 8.1 6.7 0.0 3.2 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 CCU98557.1 - 0.035 14.0 0.0 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase_2 PF01637.18 CCU98557.1 - 0.047 13.6 8.6 0.057 13.3 0.0 4.5 5 1 0 5 5 5 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 CCU98557.1 - 0.057 13.0 0.0 15 5.1 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FTA4 PF13093.6 CCU98557.1 - 0.058 13.3 3.9 0.12 12.2 3.9 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PhoH PF02562.16 CCU98557.1 - 0.069 12.6 0.0 2.6 7.4 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein AAA_25 PF13481.6 CCU98557.1 - 0.089 12.4 3.1 0.9 9.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 CCU98557.1 - 0.14 11.9 0.1 22 4.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_3 PF07726.11 CCU98557.1 - 0.14 12.0 0.0 20 5.1 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) EMP24_GP25L PF01105.24 CCU98557.1 - 0.23 11.4 0.5 0.51 10.3 0.5 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD HIP1_clath_bdg PF16515.5 CCU98557.1 - 0.24 12.0 8.6 0.068 13.8 4.2 2.4 2 0 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 CCU98557.1 - 0.43 9.4 12.0 0.72 8.7 10.8 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein LUC7 PF03194.15 CCU98557.1 - 0.72 9.5 5.7 1.7 8.2 5.7 1.6 1 0 0 1 1 1 0 LUC7 N_terminus Mod_r PF07200.13 CCU98557.1 - 1.3 9.1 11.5 1.3 9.1 9.0 2.4 2 1 0 2 2 1 0 Modifier of rudimentary (Mod(r)) protein VSG_B PF13206.6 CCU98557.1 - 1.9 7.6 5.6 3.4 6.8 5.6 1.4 1 0 0 1 1 1 0 Trypanosomal VSG domain ATPase PF06745.13 CCU98557.1 - 2.3 7.5 4.6 6.7 6.0 0.0 3.8 5 0 0 5 5 4 0 KaiC Swi5 PF07061.11 CCU98557.1 - 5.3 7.2 6.1 7.9 6.7 1.0 3.1 2 0 0 2 2 2 0 Swi5 RabGAP-TBC PF00566.18 CCU98559.1 - 3.6e-12 46.4 0.9 4.5e-12 46.1 0.9 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Acyltransferase PF01553.21 CCU98560.1 - 1.4e-30 105.6 0.0 2.1e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Saf_2TM PF18303.1 CCU98560.1 - 0.072 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain PRKCSH-like PF12999.7 CCU98561.1 - 2.4e-37 128.4 7.2 5.1e-37 127.3 7.2 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CCU98561.1 - 3e-31 108.2 1.8 3.2e-31 108.1 0.1 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CCU98561.1 - 3.1e-11 44.1 1.4 1.1e-10 42.3 0.9 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Sedlin_N PF04628.13 CCU98562.1 - 4.2e-14 52.8 0.0 1e-09 38.6 0.1 3.5 2 1 0 2 2 2 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CCU98562.1 - 8.9e-05 22.5 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family DUF3872 PF12988.7 CCU98562.1 - 0.19 11.6 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) Myb_DNA-binding PF00249.31 CCU98563.1 - 4.9e-40 135.5 16.1 2e-10 40.7 1.6 5.7 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCU98563.1 - 1.1e-29 102.4 2.3 1.5e-07 31.6 0.0 5.6 4 1 1 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CCU98563.1 - 0.0013 18.6 0.2 2.2 8.2 0.0 3.4 3 0 0 3 3 3 1 Myb DNA-binding like Rap1_C PF11626.8 CCU98563.1 - 0.0038 17.3 6.5 3.2 7.9 1.0 4.0 3 1 0 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain ARGLU PF15346.6 CCU98563.1 - 0.011 15.7 0.5 0.011 15.7 0.5 2.6 3 0 0 3 3 3 0 Arginine and glutamate-rich 1 Atg29_N PF18388.1 CCU98563.1 - 0.02 14.7 0.9 1 9.2 0.1 3.5 4 0 0 4 4 4 0 Atg29 N-terminal domain SLIDE PF09111.10 CCU98563.1 - 0.033 14.2 0.0 14 5.7 0.0 3.6 2 1 2 4 4 4 0 SLIDE DUF3606 PF12244.8 CCU98563.1 - 0.041 13.8 0.0 5.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Jag_N PF14804.6 CCU98563.1 - 0.066 13.6 0.1 0.69 10.3 0.0 2.5 2 0 0 2 2 2 0 Jag N-terminus Myb_DNA-bind_4 PF13837.6 CCU98563.1 - 0.49 10.8 10.3 11 6.5 0.5 5.0 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain GTP_EFTU PF00009.27 CCU98564.1 - 1.9e-44 151.6 0.0 2.4e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCU98564.1 - 9.6e-08 32.3 0.1 1.8e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CCU98564.1 - 1.4e-06 28.4 0.0 9e-05 22.5 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 CCU98564.1 - 0.005 16.3 0.0 3.6 7.0 0.0 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family cobW PF02492.19 CCU98564.1 - 0.021 14.4 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CCU98564.1 - 0.075 13.3 0.1 0.31 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 CCU98564.1 - 0.11 11.8 0.0 0.24 10.8 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region HBS1_N PF08938.10 CCU98565.1 - 1e-11 44.9 4.4 1.4e-11 44.6 2.6 1.9 2 0 0 2 2 2 1 HBS1 N-terminus Metal_resist PF13801.6 CCU98565.1 - 0.032 14.4 5.0 0.094 12.9 2.1 2.5 2 0 0 2 2 2 0 Heavy-metal resistance CUE PF02845.16 CCU98565.1 - 0.44 10.3 2.0 0.74 9.6 0.4 2.2 2 0 0 2 2 2 0 CUE domain CCDC24 PF15669.5 CCU98565.1 - 9 6.1 10.0 73 3.1 4.9 3.1 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Iso_dh PF00180.20 CCU98566.1 - 7.4e-87 291.7 0.0 9.4e-87 291.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CDT1 PF08839.11 CCU98567.1 - 1.2e-05 25.6 0.0 2.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like CHAT PF12770.7 CCU98567.1 - 0.03 13.8 0.6 0.056 12.8 0.6 1.4 1 0 0 1 1 1 0 CHAT domain Med13_C PF06333.12 CCU98568.1 - 5e-13 49.0 11.2 1.9e-10 40.6 2.9 2.4 1 1 1 2 2 2 2 Mediator complex subunit 13 C-terminal domain ThiF PF00899.21 CCU98570.1 - 1.6e-100 335.5 0.0 1.2e-67 227.9 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CCU98570.1 - 1.4e-90 303.6 1.3 2.1e-90 303.1 1.3 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 CCU98570.1 - 3e-33 113.8 0.9 6.3e-33 112.8 0.9 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 CCU98570.1 - 8e-27 93.8 0.0 1.5e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 CCU98570.1 - 4.1e-20 71.8 2.2 4.1e-20 71.7 0.3 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Arm PF00514.23 CCU98571.1 - 1.9 8.6 0.0 1.9 8.6 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RNA_pol_Rpb1_1 PF04997.12 CCU98572.1 - 1.8e-88 296.9 0.0 2.8e-88 296.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CCU98572.1 - 4.8e-84 281.9 0.1 7.1e-84 281.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CCU98572.1 - 3.7e-71 238.7 0.0 6.7e-71 237.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CCU98572.1 - 1.8e-38 131.9 0.0 7.7e-38 129.9 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CCU98572.1 - 7.4e-31 106.3 0.0 1.7e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-RING_7 PF02591.15 CCU98572.1 - 0.11 12.7 1.8 14 5.9 0.0 3.5 3 0 0 3 3 3 0 C4-type zinc ribbon domain zinc_ribbon_15 PF17032.5 CCU98572.1 - 0.22 12.3 0.7 0.5 11.1 0.7 1.6 1 0 0 1 1 1 0 zinc-ribbon family zf-ISL3 PF14690.6 CCU98572.1 - 1.5 9.6 5.4 0.8 10.4 0.1 3.1 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.6 CCU98572.1 - 2.8 7.5 4.7 3.6 7.1 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain RRM_1 PF00076.22 CCU98573.1 - 6.1e-40 134.9 0.0 4.1e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCU98573.1 - 7.8e-07 29.1 0.0 0.00046 20.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CCU98573.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CCU98573.1 - 0.035 14.1 0.0 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CCU98573.1 - 0.081 12.8 0.0 1 9.3 0.0 2.3 2 1 0 2 2 2 0 Occluded RNA-recognition motif FAD_binding_6 PF00970.24 CCU98574.1 - 3.2e-12 46.6 0.0 5.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 CCU98574.1 - 1.2e-08 35.5 0.6 2.1e-08 34.7 0.1 1.6 2 0 0 2 2 2 1 Globin NAD_binding_1 PF00175.21 CCU98574.1 - 2.4e-05 24.9 0.0 4.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CCU98574.1 - 0.009 16.1 0.0 0.074 13.2 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 CCU98574.1 - 0.04 13.8 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 Protoglobin Glyco_hydro_cc PF11790.8 CCU98575.1 - 5.6e-60 202.9 8.1 7.3e-60 202.5 8.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MTHFR PF02219.17 CCU98575.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase Aminotran_5 PF00266.19 CCU98577.1 - 6.9e-34 117.4 0.0 8.4e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V YoeB_toxin PF06769.14 CCU98577.1 - 0.12 12.5 0.0 0.63 10.1 0.0 2.2 2 0 0 2 2 2 0 YoeB-like toxin of bacterial type II toxin-antitoxin system TFIIF_beta PF02270.15 CCU98578.1 - 1.7e-26 92.1 0.2 3e-26 91.3 0.2 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 CCU98578.1 - 3.7e-21 76.2 0.0 7.1e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 CCU98578.1 - 0.034 14.9 0.7 0.13 13.1 0.1 2.0 1 1 1 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DDE_Tnp_IS66_C PF13817.6 CCU98578.1 - 0.14 12.4 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 IS66 C-terminal element HSP70 PF00012.20 CCU98579.1 - 6.7e-259 860.1 6.6 7.6e-259 859.9 6.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCU98579.1 - 1e-15 57.4 0.1 2.9e-14 52.7 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CCU98579.1 - 0.0021 18.4 0.4 15 6.1 0.0 3.6 3 1 0 3 3 3 1 Cell division protein FtsA BcrAD_BadFG PF01869.20 CCU98579.1 - 0.033 13.7 0.0 0.46 9.9 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 CCU98579.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 CCU98579.1 - 0.062 12.5 0.5 0.12 11.6 0.1 1.7 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase HOOK PF05622.12 CCU98580.1 - 2.3e-08 32.7 40.3 0.00096 17.4 7.6 3.0 1 1 1 2 2 2 2 HOOK protein VPS28 PF03997.12 CCU98580.1 - 0.36 10.5 7.5 0.95 9.1 1.4 2.5 2 0 0 2 2 2 0 VPS28 protein RNA_binding PF01877.17 CCU98580.1 - 2.2 8.6 6.7 3.8 7.8 0.3 2.8 2 1 0 2 2 2 0 RNA binding DUF4298 PF14131.6 CCU98580.1 - 4.5 7.3 8.3 0.88 9.6 2.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) SIKE PF05769.11 CCU98581.1 - 3.7e-05 23.7 9.4 0.00014 21.9 9.4 1.9 1 1 0 1 1 1 1 SIKE family IZUMO PF15005.6 CCU98581.1 - 0.059 13.9 1.1 0.14 12.7 1.1 1.6 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Sec2p PF06428.11 CCU98581.1 - 0.072 13.1 9.6 0.15 12.1 0.6 2.9 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p Nup54_57_C PF18570.1 CCU98581.1 - 0.15 11.6 3.7 27 4.5 0.0 3.4 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain DUF2937 PF11157.8 CCU98581.1 - 0.28 10.9 2.7 2.9 7.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DASH_Dad2 PF08654.10 CCU98581.1 - 0.6 10.6 7.0 0.17 12.3 0.4 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad2 SlyX PF04102.12 CCU98581.1 - 1.9 9.2 9.9 1.1 9.9 0.2 3.6 4 0 0 4 4 4 0 SlyX FUSC PF04632.12 CCU98581.1 - 4.9 5.6 6.8 4.4 5.7 5.9 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family ZapB PF06005.12 CCU98581.1 - 5.4 7.5 14.0 0.19 12.2 0.9 3.5 3 1 1 4 4 4 0 Cell division protein ZapB Csm1_N PF18504.1 CCU98581.1 - 9.3 6.7 9.4 4.5 7.7 0.2 3.3 4 0 0 4 4 4 0 Csm1 N-terminal domain DUF913 PF06025.12 CCU98582.1 - 7.8e-73 245.6 0.3 8.4e-72 242.2 0.0 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 CCU98582.1 - 2.8e-58 198.1 0.0 1.9e-56 192.0 0.0 2.6 1 1 0 1 1 1 1 Domain of Unknown Function (DUF908) UBA PF00627.31 CCU98582.1 - 2.5e-11 43.3 0.3 7.5e-11 41.7 0.3 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UBM PF14377.6 CCU98582.1 - 6.4e-09 35.0 1.8 6.4e-09 35.0 1.8 3.5 3 0 0 3 3 3 1 Ubiquitin binding region TH1 PF04858.13 CCU98582.1 - 0.021 13.5 0.1 0.035 12.8 0.1 1.3 1 0 0 1 1 1 0 TH1 protein Av_adeno_fibre PF06536.11 CCU98582.1 - 0.078 12.9 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Avian adenovirus fibre, N-terminal Arm PF00514.23 CCU98582.1 - 0.47 10.6 7.9 0.28 11.3 0.4 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cullin PF00888.22 CCU98583.1 - 1.4e-73 248.6 0.0 1.8e-73 248.2 0.0 1.1 1 0 0 1 1 1 1 Cullin family BPL_LplA_LipB PF03099.19 CCU98584.1 - 7.1e-16 58.3 0.0 1.4e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.9 CCU98584.1 - 5e-06 25.8 0.0 0.00011 21.5 0.0 2.8 3 1 0 3 3 3 1 Biotin-protein ligase, N terminal PrpR_N PF06506.11 CCU98584.1 - 0.22 11.1 0.1 0.36 10.4 0.1 1.3 1 0 0 1 1 1 0 Propionate catabolism activator Hydrolase_6 PF13344.6 CCU98585.1 - 8.9e-29 99.6 0.0 1.6e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCU98585.1 - 2.7e-18 65.8 0.0 7.2e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 CCU98585.1 - 7.7e-08 32.6 0.0 0.001 19.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCU98585.1 - 4.3e-07 30.4 0.0 6.4e-06 26.6 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ion_trans PF00520.31 CCU98585.1 - 0.0014 17.9 3.3 0.0021 17.3 3.3 1.1 1 0 0 1 1 1 1 Ion transport protein PGP_phosphatase PF09419.10 CCU98585.1 - 0.083 12.5 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 CCU98585.1 - 0.3 10.6 0.0 0.48 10.0 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Pkinase PF00069.25 CCU98586.1 - 1.7e-27 96.5 0.0 2.1e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98586.1 - 2.4e-17 63.1 0.0 3e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCU98586.1 - 3.2e-09 36.1 0.0 4.4e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CCU98586.1 - 0.00084 19.3 0.0 0.0085 16.0 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CCU98586.1 - 0.056 12.4 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 CCU98586.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AA_permease_2 PF13520.6 CCU98587.1 - 1.2e-65 222.1 50.1 1.4e-65 221.8 50.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCU98587.1 - 1.3e-35 123.0 42.6 1.6e-35 122.6 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease Phage_holin_4_1 PF05105.12 CCU98587.1 - 5.8 7.1 12.2 0.13 12.4 1.3 2.9 3 0 0 3 3 3 0 Bacteriophage holin family MFS_1 PF07690.16 CCU98588.1 - 3.7e-20 72.2 21.0 3.7e-20 72.2 21.0 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Utp11 PF03998.13 CCU98589.1 - 3.1e-61 207.4 15.6 3.8e-61 207.1 15.6 1.1 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 CCU98589.1 - 0.023 14.1 0.2 0.041 13.2 0.2 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF1774 PF08611.10 CCU98590.1 - 0.015 15.6 0.3 0.015 15.6 0.3 2.6 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF1774) Arrestin_N PF00339.29 CCU98591.1 - 5.2e-07 29.8 0.0 3.2e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ADH_N PF08240.12 CCU98592.1 - 9.2e-26 89.9 0.7 2.2e-25 88.6 0.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCU98592.1 - 2.6e-21 75.9 0.1 5.1e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CCU98592.1 - 0.002 17.5 0.4 0.0032 16.8 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CCU98592.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FGGY_C PF02782.16 CCU98593.1 - 4.1e-40 137.6 0.5 7.2e-40 136.8 0.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CCU98593.1 - 1.1e-19 71.0 0.0 5.8e-18 65.3 0.0 2.7 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 CCU98593.1 - 0.17 11.8 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Hexokinase Glyco_transf_21 PF13506.6 CCU98594.1 - 4.5e-24 84.9 1.2 2.7e-09 36.8 0.1 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CCU98594.1 - 3.6e-13 49.9 0.5 7.1e-13 49.0 0.5 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 UQ_con PF00179.26 CCU98595.1 - 1.5e-40 138.1 0.1 1.7e-40 137.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CCU98595.1 - 0.0096 16.2 0.2 0.017 15.4 0.2 1.5 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CCU98595.1 - 0.02 14.6 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Tropomyosin_1 PF12718.7 CCU98596.1 - 3.2e-33 114.9 30.9 1.3e-32 112.9 30.9 1.8 1 1 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 CCU98596.1 - 4.2e-08 32.9 28.2 0.00055 19.4 4.2 3.0 1 1 2 3 3 3 3 Tropomyosin KELK PF15796.5 CCU98596.1 - 0.00057 20.3 6.1 0.00057 20.3 6.1 3.2 1 1 2 3 3 3 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase CCDC-167 PF15188.6 CCU98596.1 - 0.0018 18.6 5.8 0.0018 18.6 5.8 2.7 1 1 2 3 3 3 1 Coiled-coil domain-containing protein 167 FliD_C PF07195.12 CCU98596.1 - 0.0023 17.4 4.9 0.0023 17.4 4.9 2.1 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus TMF_DNA_bd PF12329.8 CCU98596.1 - 0.011 15.7 9.3 0.011 15.7 9.3 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GAS PF13851.6 CCU98596.1 - 0.055 12.8 24.0 0.13 11.6 24.0 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 CCU98596.1 - 0.069 13.4 23.7 0.037 14.2 12.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 CCU98596.1 - 0.085 12.9 22.0 1.1 9.4 12.1 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase HOOK PF05622.12 CCU98596.1 - 0.12 10.6 22.8 0.15 10.2 22.8 1.2 1 0 0 1 1 1 0 HOOK protein Csm1_N PF18504.1 CCU98596.1 - 0.15 12.4 24.5 0.45 10.9 5.3 3.4 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF5320 PF17253.2 CCU98596.1 - 0.22 12.6 0.3 0.22 12.6 0.3 3.2 1 1 2 3 3 3 0 Family of unknown function (DUF5320) GTP-bdg_M PF16360.5 CCU98596.1 - 0.23 12.1 10.4 0.53 10.9 2.2 2.7 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region PIN_8 PF18476.1 CCU98596.1 - 0.31 10.9 11.1 0.59 9.9 11.1 1.4 1 1 0 1 1 1 0 PIN like domain DUF725 PF05267.12 CCU98596.1 - 0.43 10.6 6.4 0.066 13.2 1.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF725) Prefoldin_3 PF13758.6 CCU98596.1 - 0.46 10.6 14.2 0.25 11.4 4.9 2.6 1 1 1 2 2 2 0 Prefoldin subunit DHR10 PF18595.1 CCU98596.1 - 0.64 10.1 31.6 0.78 9.8 10.7 3.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CLZ PF16526.5 CCU98596.1 - 0.7 10.3 23.8 3.7 8.0 1.7 3.1 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cob_adeno_trans PF01923.18 CCU98596.1 - 0.79 9.8 6.3 1.9 8.6 6.3 1.8 1 1 0 1 1 1 0 Cobalamin adenosyltransferase DUF4407 PF14362.6 CCU98596.1 - 0.84 8.9 20.0 1.5 8.1 20.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Hsk3 PF08227.11 CCU98596.1 - 0.85 10.0 4.9 1.7 9.0 0.6 2.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like ERM PF00769.19 CCU98596.1 - 0.92 9.3 29.0 2.3 8.0 9.1 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DLP_helical PF18709.1 CCU98596.1 - 1.1 8.3 13.2 1.7 7.8 13.2 1.4 1 1 0 1 1 1 0 Dynamin-like helical domain FAM76 PF16046.5 CCU98596.1 - 1.1 8.5 14.8 1.7 7.9 14.8 1.3 1 0 0 1 1 1 0 FAM76 protein Occludin_ELL PF07303.13 CCU98596.1 - 1.4 9.7 12.8 3.6 8.3 2.7 2.9 1 1 1 2 2 2 0 Occludin homology domain Prefoldin PF02996.17 CCU98596.1 - 1.6 8.7 18.0 3.5 7.6 2.1 3.3 1 1 2 3 3 3 0 Prefoldin subunit NPV_P10 PF05531.12 CCU98596.1 - 1.7 9.2 7.0 6.9 7.2 3.5 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4472 PF14739.6 CCU98596.1 - 1.7 9.4 22.8 2.6 8.8 9.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Swi5 PF07061.11 CCU98596.1 - 1.9 8.7 17.3 3.9 7.6 5.2 3.4 1 1 3 4 4 4 0 Swi5 DUF724 PF05266.14 CCU98596.1 - 2.3 8.0 20.1 3 7.6 7.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF883 PF05957.13 CCU98596.1 - 4.9 7.8 11.3 0.42 11.2 5.1 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) GrpE PF01025.19 CCU98596.1 - 5.2 6.7 25.2 12 5.6 7.0 2.4 1 1 1 2 2 2 0 GrpE LMBR1 PF04791.16 CCU98596.1 - 5.2 5.9 12.4 5.6 5.7 12.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Phage_GPO PF05929.11 CCU98596.1 - 5.7 6.5 14.6 0.66 9.5 8.2 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Prefoldin_2 PF01920.20 CCU98596.1 - 5.8 6.9 24.0 8.1 6.5 5.0 3.2 1 1 2 3 3 3 0 Prefoldin subunit Exonuc_VII_L PF02601.15 CCU98596.1 - 6.4 6.3 16.3 29 4.1 16.3 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit UPF0184 PF03670.13 CCU98596.1 - 7.6 7.0 13.0 2.7 8.4 5.7 2.8 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) AIF-MLS PF14962.6 CCU98596.1 - 8.6 6.3 9.6 4 7.4 7.5 1.5 1 1 1 2 2 2 0 Mitochondria Localisation Sequence Pkinase PF00069.25 CCU98597.1 - 4.5e-47 160.6 0.0 4.3e-23 82.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98597.1 - 2.2e-15 56.6 0.1 1.2e-11 44.4 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CCU98597.1 - 0.0012 18.8 0.7 0.0041 17.1 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CCU98597.1 - 0.0035 16.7 0.2 0.0076 15.6 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CCU98597.1 - 0.0066 15.4 0.2 0.011 14.6 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CCU98597.1 - 0.13 11.9 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 CCU98597.1 - 0.21 10.8 0.1 0.62 9.3 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Myosin_head PF00063.21 CCU98599.1 - 6.3e-255 847.6 0.0 2.8e-254 845.5 0.0 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 CCU98599.1 - 8.9e-28 96.6 1.7 8.9e-28 96.6 1.7 2.7 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 CCU98599.1 - 1.9e-05 24.1 37.6 0.00056 19.5 0.5 6.7 7 0 0 7 7 7 4 IQ calmodulin-binding motif AAA_22 PF13401.6 CCU98599.1 - 0.00021 21.5 0.0 0.001 19.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain ABC_tran_CTD PF16326.5 CCU98599.1 - 0.0073 16.5 1.7 0.0073 16.5 1.7 3.2 1 1 2 3 3 3 1 ABC transporter C-terminal domain Myosin_N PF02736.19 CCU98599.1 - 0.055 13.3 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Baculo_PEP_C PF04513.12 CCU98599.1 - 0.095 12.7 2.7 0.33 11.0 2.7 2.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 CCU98599.1 - 0.15 12.2 10.8 0.12 12.5 5.4 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AAA_16 PF13191.6 CCU98599.1 - 0.4 11.0 0.0 0.4 11.0 0.0 3.6 2 1 1 3 3 2 0 AAA ATPase domain ABC_tran PF00005.27 CCU98599.1 - 0.56 10.7 3.3 2.4 8.7 0.0 2.8 2 1 0 2 2 2 0 ABC transporter CENP-F_leu_zip PF10473.9 CCU98599.1 - 0.68 10.0 16.6 1.8 8.6 16.6 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 CCU98599.1 - 0.7 8.4 6.1 1.2 7.7 6.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Csm1_N PF18504.1 CCU98599.1 - 0.91 9.9 19.3 2.2 8.7 5.2 4.0 2 2 1 3 3 3 0 Csm1 N-terminal domain Phage_GP20 PF06810.11 CCU98599.1 - 1.1 9.0 4.8 3.4 7.5 4.6 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF5082 PF16888.5 CCU98599.1 - 3.3 8.0 10.2 0.093 13.0 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) FlaC_arch PF05377.11 CCU98599.1 - 3.8 8.0 4.4 40 4.7 0.3 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.17 CCU98599.1 - 4.8 7.1 8.6 26 4.8 0.8 3.4 3 0 0 3 3 3 0 Prefoldin subunit Seryl_tRNA_N PF02403.22 CCU98599.1 - 8.2 6.7 19.7 0.028 14.7 6.3 3.0 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain TSC22 PF01166.18 CCU98599.1 - 8.2 6.8 8.5 49 4.3 1.8 3.8 4 0 0 4 4 4 0 TSC-22/dip/bun family AA_permease PF00324.21 CCU98600.1 - 1.4e-62 211.9 32.7 1.7e-62 211.6 32.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCU98600.1 - 1.9e-18 66.5 40.3 2.7e-18 66.0 40.3 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 CCU98600.1 - 2.3e-14 53.2 0.0 6.4e-10 38.6 0.0 3.1 3 0 0 3 3 3 2 Solute carrier family 12 PRP38 PF03371.15 CCU98601.1 - 8.9e-61 204.8 0.3 1.1e-60 204.5 0.3 1.1 1 0 0 1 1 1 1 PRP38 family APG6_N PF17675.1 CCU98601.1 - 0.11 13.0 2.8 0.17 12.4 2.8 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Phage_tail_APC PF16778.5 CCU98601.1 - 0.22 11.4 2.3 0.55 10.1 2.3 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Kinesin PF00225.23 CCU98602.1 - 5e-93 311.7 0.0 6.5e-93 311.3 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CCU98602.1 - 6e-18 65.2 0.0 1.1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding TSC22 PF01166.18 CCU98602.1 - 0.2 12.0 1.4 35 4.8 0.2 3.8 3 0 0 3 3 3 0 TSC-22/dip/bun family FUSC PF04632.12 CCU98602.1 - 0.31 9.5 16.3 0.054 12.0 11.3 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family AAA PF00004.29 CCU98603.1 - 8.8e-41 139.4 0.0 1.1e-39 135.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CCU98603.1 - 1.1e-19 70.2 0.1 2.1e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CCU98603.1 - 4.3e-11 42.4 0.2 1.1e-10 41.2 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CCU98603.1 - 6e-05 23.2 0.1 0.00085 19.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCU98603.1 - 0.00012 22.0 0.6 0.00062 19.8 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCU98603.1 - 0.00022 21.6 0.2 0.049 14.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CCU98603.1 - 0.00043 20.1 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCU98603.1 - 0.00054 20.3 0.6 0.11 12.8 0.6 2.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 CCU98603.1 - 0.00092 18.7 2.6 0.014 14.9 0.0 3.0 3 0 0 3 3 3 1 PhoH-like protein AAA_33 PF13671.6 CCU98603.1 - 0.01 16.0 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CCU98603.1 - 0.012 15.4 0.1 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CCU98603.1 - 0.014 14.8 0.0 0.047 13.1 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CCU98603.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.13 CCU98603.1 - 0.078 12.1 0.2 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 CCU98603.1 - 0.094 12.7 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCU98603.1 - 0.12 13.0 0.1 1.1 9.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CCU98603.1 - 0.14 11.8 0.1 0.34 10.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain Med4 PF10018.9 CCU98604.1 - 2.1e-16 60.2 0.2 2.9e-16 59.7 0.2 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Spectrin PF00435.21 CCU98604.1 - 0.00084 19.8 1.8 0.0013 19.2 1.8 1.3 1 0 0 1 1 1 1 Spectrin repeat ATG16 PF08614.11 CCU98604.1 - 0.017 15.4 5.1 0.024 14.9 5.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 CCU98604.1 - 0.29 9.6 8.6 0.34 9.4 8.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pkinase PF00069.25 CCU98605.1 - 3.7e-53 180.6 0.0 4.8e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98605.1 - 5.2e-18 65.3 0.1 8.9e-18 64.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CCU98605.1 - 0.00072 19.2 0.1 0.0016 18.1 0.1 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 CCU98605.1 - 0.0034 17.3 0.1 0.015 15.2 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CCU98605.1 - 0.055 13.0 0.2 0.085 12.4 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PilZ_2 PF16823.5 CCU98605.1 - 0.14 12.3 0.3 0.27 11.4 0.3 1.5 1 0 0 1 1 1 0 Atypical PilZ domain, cyclic di-GMP receptor HEAT_EZ PF13513.6 CCU98606.1 - 2.8e-26 91.6 13.3 2e-05 25.0 0.0 10.4 9 1 1 10 10 10 5 HEAT-like repeat HEAT_2 PF13646.6 CCU98606.1 - 4.5e-17 62.2 16.9 0.031 14.7 0.3 8.4 4 3 3 8 8 8 5 HEAT repeats HEAT PF02985.22 CCU98606.1 - 4.3e-15 54.5 11.0 0.019 15.2 0.0 10.8 12 0 0 12 12 10 4 HEAT repeat UME PF08064.13 CCU98606.1 - 1.4e-09 37.8 0.4 0.38 10.7 0.0 6.3 6 1 1 7 7 7 3 UME (NUC010) domain MMS19_C PF12460.8 CCU98606.1 - 2.2e-08 33.6 0.0 0.043 12.9 0.2 5.9 4 2 2 6 6 6 3 RNAPII transcription regulator C-terminal Xpo1 PF08389.12 CCU98606.1 - 2e-06 27.9 4.8 0.013 15.6 0.2 4.9 4 1 1 5 5 5 2 Exportin 1-like protein Cnd1 PF12717.7 CCU98606.1 - 2.9e-06 27.4 0.3 0.31 11.1 0.0 4.1 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 CCU98606.1 - 9.2e-06 25.5 1.5 3.4e-05 23.7 0.2 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 CCU98606.1 - 1.7e-05 25.3 0.1 1.6 9.4 0.0 6.1 7 1 1 8 8 7 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CCU98606.1 - 1.9e-05 24.3 0.1 0.41 10.2 0.0 4.6 4 2 1 5 5 5 2 CLASP N terminal MMS19_N PF14500.6 CCU98606.1 - 2.9e-05 23.8 1.1 0.076 12.6 0.9 4.0 3 1 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II Ipi1_N PF12333.8 CCU98606.1 - 0.00011 22.7 0.0 1.6 9.3 0.0 5.3 4 1 1 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.20 CCU98606.1 - 0.00022 20.0 2.4 0.4 9.2 0.2 3.8 4 1 0 4 4 4 2 Adaptin N terminal region Cohesin_HEAT PF12765.7 CCU98606.1 - 0.011 16.0 0.6 12 6.4 0.0 3.7 3 0 0 3 3 2 0 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 CCU98606.1 - 0.14 11.3 0.5 16 4.5 0.1 2.8 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain DUF2267 PF10025.9 CCU98606.1 - 0.34 11.2 2.3 5.7 7.2 0.2 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) SWI-SNF_Ssr4 PF08549.10 CCU98607.1 - 5.2e-07 28.7 4.4 1e-05 24.5 0.0 2.4 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1750) Nop16 PF09420.10 CCU98607.1 - 0.0014 18.8 1.8 0.0015 18.6 1.8 1.3 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 TMF_TATA_bd PF12325.8 CCU98607.1 - 6.3 7.0 7.6 4.6 7.5 1.1 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding RabGAP-TBC PF00566.18 CCU98609.1 - 1.6e-07 31.2 0.0 1.6e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain BAR PF03114.18 CCU98610.1 - 1e-34 120.3 4.9 1.7e-34 119.5 4.9 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 CCU98610.1 - 1.2e-15 56.8 0.0 1.9e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCU98610.1 - 1.8e-12 46.9 0.1 2.9e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCU98610.1 - 5.4e-11 42.0 0.0 8.3e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF4375 PF14300.6 CCU98610.1 - 0.069 13.4 1.6 0.17 12.1 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) DUF2935 PF11155.8 CCU98610.1 - 0.12 12.7 3.8 4.5 7.6 0.2 3.5 3 2 0 3 3 3 0 Domain of unknown function (DUF2935) STAT_alpha PF01017.20 CCU98610.1 - 0.3 10.9 3.3 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 STAT protein, all-alpha domain IF-2B PF01008.17 CCU98611.1 - 1e-69 234.9 0.0 1.8e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family Med3 PF11593.8 CCU98611.1 - 0.45 9.6 4.3 0.62 9.2 4.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Dynein_light PF01221.18 CCU98612.1 - 2e-31 108.1 1.7 5.6e-31 106.7 1.7 1.6 1 1 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 CCU98612.1 - 0.033 14.9 0.3 0.051 14.3 0.3 1.3 1 1 0 1 1 1 0 Ground-like domain DUF2335 PF10097.9 CCU98612.1 - 0.054 13.5 0.8 0.075 13.0 0.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) MutL_C PF08676.11 CCU98613.1 - 1.3e-19 70.4 0.3 3.5e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CCU98613.1 - 6.6e-18 64.5 0.0 1.2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CCU98613.1 - 0.081 12.8 0.0 0.28 11.0 0.0 2.0 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WD40 PF00400.32 CCU98614.1 - 0.00012 22.8 0.1 0.00059 20.6 0.1 2.3 1 1 0 1 1 1 1 WD domain, G-beta repeat V-ATPase_G PF03179.15 CCU98615.1 - 1.5e-27 96.2 19.8 1.8e-27 95.9 19.8 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 CCU98615.1 - 0.0002 20.8 13.6 0.00025 20.5 13.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ATP-synt_B PF00430.18 CCU98615.1 - 0.0059 16.7 14.4 0.0059 16.7 14.4 1.9 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 CCU98615.1 - 0.017 15.5 17.4 0.031 14.7 17.3 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Exonuc_VII_L PF02601.15 CCU98615.1 - 0.19 11.2 6.3 0.23 11.0 6.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_11 PF13086.6 CCU98615.1 - 0.22 11.3 7.7 0.27 11.0 7.7 1.1 1 0 0 1 1 1 0 AAA domain Phasin PF05597.11 CCU98615.1 - 0.37 10.8 10.5 0.9 9.6 10.5 1.6 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GCP_C_terminal PF04130.13 CCU98615.1 - 0.47 9.9 6.8 0.75 9.2 6.8 1.4 1 1 0 1 1 1 0 Gamma tubulin complex component C-terminal RRF PF01765.19 CCU98615.1 - 0.81 9.6 14.0 1.3 9.0 13.9 1.4 1 1 0 1 1 1 0 Ribosome recycling factor Hid1 PF12722.7 CCU98615.1 - 0.86 7.7 6.5 1.1 7.4 6.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein OmpH PF03938.14 CCU98615.1 - 1.1 9.5 23.0 2 8.8 23.0 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FapA PF03961.13 CCU98615.1 - 1.3 7.6 10.2 1.5 7.3 10.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 CCU98615.1 - 1.4 8.2 10.8 1.7 7.9 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PTPlike_phytase PF14566.6 CCU98615.1 - 1.8 8.6 5.8 2.4 8.3 5.8 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Remorin_C PF03763.13 CCU98615.1 - 2.2 8.2 19.6 0.47 10.4 1.0 2.6 1 1 1 2 2 2 0 Remorin, C-terminal region Zip PF02535.22 CCU98615.1 - 2.4 7.3 3.5 2.9 7.0 3.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_L28e PF01778.17 CCU98615.1 - 2.9 8.7 6.5 2.2 9.1 1.6 2.1 1 1 1 2 2 2 0 Ribosomal L28e protein family DUF883 PF05957.13 CCU98615.1 - 4.4 8.0 9.9 23 5.7 4.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.13 CCU98615.1 - 5.1 6.2 11.4 6.4 5.9 11.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Symplekin_C PF12295.8 CCU98616.1 - 4.2e-53 180.2 0.3 4.2e-53 180.2 0.3 2.0 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 CCU98616.1 - 1.4e-37 129.5 0.1 3.5e-37 128.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Trp_syntA PF00290.20 CCU98617.1 - 5.8e-85 284.3 0.3 1.1e-84 283.4 0.3 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 CCU98617.1 - 1.5e-46 159.2 1.7 3.1e-46 158.1 1.7 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.25 CCU98618.1 - 2.1e-58 197.8 0.0 3.3e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98618.1 - 6e-38 130.6 0.0 8.8e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CCU98618.1 - 3.1e-20 72.3 0.0 7.9e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Rad9 PF04139.13 CCU98618.1 - 1.4e-10 41.0 0.0 2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Rad9 Pkinase_fungal PF17667.1 CCU98618.1 - 1.1e-06 27.8 0.0 1.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CCU98618.1 - 1.7e-05 24.3 0.2 3.6e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CCU98618.1 - 0.067 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CCU98618.1 - 0.085 12.8 0.1 0.5 10.3 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CCU98618.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UDPGP PF01704.18 CCU98620.1 - 8.6e-49 166.3 0.0 1.1e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CCU98620.1 - 0.013 15.8 0.1 0.046 14.1 0.0 2.0 1 1 0 1 1 1 0 MobA-like NTP transferase domain tRNA_bind PF01588.20 CCU98621.1 - 8.7e-25 86.7 0.0 1.5e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 CCU98621.1 - 1.9e-05 24.8 0.0 1.9e-05 24.8 0.0 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCU98621.1 - 3.4e-05 23.8 0.0 0.00013 21.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CCU98621.1 - 0.00052 19.8 0.1 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCU98621.1 - 0.014 15.5 1.1 0.024 14.8 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain RNA_pol_Rpc4 PF05132.14 CCU98621.1 - 0.023 15.1 5.1 0.038 14.4 5.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 IHABP4_N PF16174.5 CCU98621.1 - 0.16 12.6 11.5 0.27 11.8 11.5 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal RR_TM4-6 PF06459.12 CCU98621.1 - 0.61 9.9 4.6 1 9.2 4.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FGF-BP1 PF06473.12 CCU98621.1 - 4.4 7.1 7.7 3.3 7.5 6.1 1.5 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) DUF3464 PF11947.8 CCU98621.1 - 5.6 6.7 5.4 2.5e+02 1.3 8.3 2.0 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 LRR_8 PF13855.6 CCU98622.1 - 1.3e-17 63.3 23.4 1.8e-10 40.4 4.7 4.9 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CCU98622.1 - 2.4e-13 50.0 24.0 0.00025 21.3 1.8 5.5 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) Torus PF16131.5 CCU98622.1 - 3.3e-08 34.2 4.7 0.0032 18.2 0.3 2.5 1 1 1 2 2 2 2 Torus domain LRR_6 PF13516.6 CCU98622.1 - 2.4e-07 30.2 25.1 0.016 15.2 0.2 7.7 8 0 0 8 8 8 3 Leucine Rich repeat zf-CCCH_4 PF18044.1 CCU98622.1 - 6.1e-07 29.1 10.0 0.00045 19.9 1.6 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 CCU98622.1 - 4.9e-06 26.3 6.5 0.00042 20.2 0.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_1 PF00560.33 CCU98622.1 - 1.1e-05 25.3 11.4 5.9 7.9 0.1 7.6 7 1 0 7 7 7 2 Leucine Rich Repeat zf_CCCH_4 PF18345.1 CCU98622.1 - 0.00011 22.1 14.6 0.0009 19.2 3.5 2.4 2 0 0 2 2 2 2 Zinc finger domain LRR_3 PF07725.12 CCU98622.1 - 0.0014 18.4 4.8 0.47 10.4 0.1 4.3 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.6 CCU98622.1 - 0.0014 18.1 0.6 1.2 8.6 0.1 2.3 2 0 0 2 2 2 2 Leucine-rich repeat zf-CCCH_3 PF15663.5 CCU98622.1 - 0.0017 18.5 0.3 0.0033 17.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 CCU98622.1 - 0.99 10.0 13.3 0.049 14.1 4.7 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger GCV_T PF01571.21 CCU98623.1 - 4.6e-78 262.1 0.0 6e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CCU98623.1 - 1.4e-20 72.9 0.1 3.4e-20 71.8 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 CCU98623.1 - 0.04 14.1 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family ABC_membrane PF00664.23 CCU98624.1 - 7.1e-46 157.1 20.1 1.4e-27 97.1 8.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCU98624.1 - 2.5e-43 147.9 0.0 1e-25 90.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCU98624.1 - 1e-10 41.4 0.1 0.011 15.2 0.1 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CCU98624.1 - 1e-07 32.3 0.1 0.024 14.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CCU98624.1 - 7.2e-07 28.9 0.0 0.00039 20.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CCU98624.1 - 1.9e-06 27.9 0.0 0.12 12.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CCU98624.1 - 9.7e-06 26.1 0.1 0.021 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 CCU98624.1 - 2.7e-05 24.8 0.0 0.041 14.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 CCU98624.1 - 6.2e-05 22.2 0.0 0.0038 16.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 CCU98624.1 - 0.00076 19.9 0.0 0.23 11.9 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 CCU98624.1 - 0.00089 18.7 0.0 0.61 9.4 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_7 PF12775.7 CCU98624.1 - 0.0019 17.7 0.0 0.63 9.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 CCU98624.1 - 0.0021 17.8 0.0 0.23 11.2 0.0 3.0 2 2 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 CCU98624.1 - 0.006 15.6 0.0 0.83 8.5 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 CCU98624.1 - 0.006 16.5 0.0 5.5 6.9 0.0 2.8 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 CCU98624.1 - 0.0066 16.1 0.6 4 7.0 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 CCU98624.1 - 0.011 15.5 0.1 0.73 9.6 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 CCU98624.1 - 0.015 14.5 0.0 4.4 6.4 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain DUF87 PF01935.17 CCU98624.1 - 0.018 15.1 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 CCU98624.1 - 0.019 15.0 0.0 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase TsaE PF02367.17 CCU98624.1 - 0.021 14.8 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 CCU98624.1 - 0.021 14.5 0.0 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 CCU98624.1 - 0.021 14.8 0.1 4.8 7.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CCU98624.1 - 0.022 15.1 0.0 4.9 7.6 0.0 2.7 3 0 0 3 3 2 0 RNA helicase AAA_33 PF13671.6 CCU98624.1 - 0.028 14.6 0.1 5.1 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CCU98624.1 - 0.037 13.9 0.0 4.7 7.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 CCU98624.1 - 0.083 12.5 0.0 5.7 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CCU98624.1 - 0.09 12.5 1.5 3.2 7.5 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein Roc PF08477.13 CCU98624.1 - 0.19 12.0 0.1 5 7.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 CCU98624.1 - 0.2 11.4 0.2 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 CCU98624.1 - 0.21 11.3 0.0 0.77 9.4 0.0 1.9 3 0 0 3 3 2 0 AAA domain TMEM213 PF15192.6 CCU98624.1 - 2.2 8.3 4.0 5.8 7.0 4.0 1.7 1 0 0 1 1 1 0 TMEM213 family NUFIP1 PF10453.9 CCU98625.1 - 2.2e-11 43.4 0.5 4.1e-11 42.5 0.5 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) EFTUD2 PF16004.5 CCU98625.1 - 0.015 15.9 1.4 0.15 12.6 0.0 2.4 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus SOG2 PF10428.9 CCU98625.1 - 0.25 10.5 8.4 0.33 10.1 8.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 CCU98625.1 - 5.2 6.9 15.5 8.8 6.1 15.5 1.3 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CCU98625.1 - 9.5 4.9 8.2 13 4.5 8.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribosomal_L4 PF00573.22 CCU98626.1 - 1.6e-58 197.5 0.0 2e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.19 CCU98627.1 - 8.6e-32 110.2 0.3 9.8e-32 110.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 SWIB PF02201.18 CCU98628.1 - 2e-20 72.4 0.0 3.5e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Med3 PF11593.8 CCU98628.1 - 0.75 8.9 3.5 1.5 7.9 3.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ras PF00071.22 CCU98629.1 - 1.5e-58 197.0 0.0 1.7e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCU98629.1 - 1.2e-36 125.6 0.0 1.7e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU98629.1 - 1.2e-17 63.9 0.0 9e-17 61.1 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCU98629.1 - 2.3e-09 37.0 0.0 3e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCU98629.1 - 7.8e-05 22.3 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CCU98629.1 - 0.00012 22.2 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CCU98629.1 - 0.0016 18.9 0.0 0.0025 18.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CCU98629.1 - 0.0044 16.9 0.1 0.64 9.9 0.0 2.5 2 1 0 2 2 2 1 RsgA GTPase TniB PF05621.11 CCU98629.1 - 0.0084 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein SRPRB PF09439.10 CCU98629.1 - 0.029 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 CCU98629.1 - 0.033 14.1 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 NTPase Mito_carr PF00153.27 CCU98630.1 - 3e-63 209.8 5.0 1.3e-22 79.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CCU98630.1 - 0.012 14.8 0.1 0.024 13.9 0.1 1.4 1 0 0 1 1 1 0 Fuseless Glyco_hydro_88 PF07470.13 CCU98630.1 - 0.06 12.4 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 SEP PF08059.13 CCU98631.1 - 1.6e-25 89.5 0.0 7.1e-25 87.4 0.0 2.2 3 0 0 3 3 3 1 SEP domain UBA_4 PF14555.6 CCU98631.1 - 3.8e-09 36.2 0.0 6.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 CCU98631.1 - 1.1e-06 28.7 0.0 1.8e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 UBX domain Tim17 PF02466.19 CCU98632.1 - 1.3e-07 32.0 13.5 2.9e-07 30.9 13.3 1.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ERAP1_C PF11838.8 CCU98633.1 - 1.4e-72 244.9 1.0 2.1e-72 244.4 1.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 CCU98633.1 - 1.6e-68 230.5 0.2 2.6e-68 229.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CCU98633.1 - 5.6e-38 131.0 0.0 1.9e-36 126.0 0.0 2.5 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 CCU98634.1 - 4.5e-65 219.3 0.1 7.9e-65 218.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CCU98634.1 - 1.5e-64 218.5 5.1 2.4e-64 217.9 5.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CCU98634.1 - 5.1e-31 108.3 0.0 1.8e-29 103.3 0.0 2.7 2 1 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 CCU98634.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Aldo_ket_red PF00248.21 CCU98635.1 - 4.8e-40 137.6 0.2 5e-38 131.0 0.2 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Peptidase_M19 PF01244.21 CCU98635.1 - 0.054 12.6 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) ERAP1_C PF11838.8 CCU98636.1 - 2.5e-65 221.1 7.4 4.8e-65 220.2 7.4 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 CCU98636.1 - 2.1e-63 213.8 0.0 3.9e-63 212.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CCU98636.1 - 3.3e-29 102.4 0.0 9.5e-28 97.6 0.0 2.6 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Aminotran_1_2 PF00155.21 CCU98638.1 - 6.9e-46 157.1 0.0 7.9e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CCU98638.1 - 0.005 15.4 0.0 0.0093 14.5 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CCU98638.1 - 0.0087 15.4 0.2 0.039 13.2 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase BetR PF08667.10 CCU98638.1 - 0.052 13.6 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 BetR domain Vps39_1 PF10366.9 CCU98639.1 - 1.4e-21 76.8 0.1 6.8e-21 74.6 0.0 2.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 CCU98639.1 - 3.9e-16 59.5 0.0 9.9e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 CCU98639.1 - 2.6e-07 30.5 0.0 8.6e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 CCU98639.1 - 0.0011 18.8 0.0 1.6 8.6 0.0 2.7 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_10 PF13374.6 CCU98639.1 - 1.2 9.1 12.1 1.2 9.1 0.5 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ASH PF15780.5 CCU98640.1 - 3.6e-08 33.5 0.0 0.0057 16.8 0.0 5.8 7 0 0 7 7 7 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CCU98640.1 - 3.2e-07 30.4 0.1 0.014 15.5 0.1 3.9 4 0 0 4 4 4 3 Flagellar-associated PapD-like TMEM131_like PF12371.8 CCU98640.1 - 0.00018 21.7 0.1 0.2 11.9 0.0 3.5 2 1 1 3 3 3 2 Transmembrane protein 131-like Kinesin PF00225.23 CCU98641.1 - 3.2e-104 348.4 0.0 4.5e-104 348.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CCU98641.1 - 3.1e-23 82.4 0.0 6.1e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding DUF4407 PF14362.6 CCU98641.1 - 7.3e-05 22.3 5.3 0.017 14.5 4.9 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) Bac_DnaA PF00308.18 CCU98641.1 - 0.02 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AIP3 PF03915.13 CCU98641.1 - 0.16 11.0 2.0 0.39 9.7 2.0 1.7 1 1 0 1 1 1 0 Actin interacting protein 3 DUF724 PF05266.14 CCU98641.1 - 6 6.6 7.1 21 4.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) NPR3 PF03666.13 CCU98643.1 - 1.3e-59 202.3 3.7 4.2e-48 164.3 0.0 2.4 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 CCU98643.1 - 1.7e-06 27.1 0.1 8.8e-06 24.7 0.0 2.1 3 0 0 3 3 3 1 Nitrogen permease regulator 2 CN_hydrolase PF00795.22 CCU98645.1 - 0.00055 19.4 0.0 0.012 15.0 0.0 2.3 2 1 0 2 2 2 1 Carbon-nitrogen hydrolase BolA PF01722.18 CCU98646.1 - 8.1e-17 61.3 0.0 1.6e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 BolA-like protein UvrD-helicase PF00580.21 CCU98647.1 - 1.7e-14 54.0 0.0 1.2e-10 41.5 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CCU98647.1 - 5.2e-12 45.8 0.0 8.3e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CCU98647.1 - 1.9e-11 44.5 0.0 5.3e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CCU98647.1 - 8.1e-11 41.6 0.3 4.5e-10 39.2 0.3 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CCU98647.1 - 1.7e-08 34.5 0.0 0.026 14.3 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CCU98647.1 - 4.4e-07 29.8 0.0 0.0008 19.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 CCU98647.1 - 0.002 17.6 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.6 CCU98647.1 - 0.051 13.8 0.0 1.6 9.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_12 PF13087.6 CCU98647.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain HEAT_EZ PF13513.6 CCU98648.1 - 0.00015 22.2 16.8 2.8 8.6 0.0 6.9 6 0 0 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 CCU98648.1 - 0.017 15.5 1.5 0.017 15.5 1.5 5.7 7 0 0 7 7 7 0 HEAT repeats Cnd1 PF12717.7 CCU98648.1 - 0.018 15.1 0.0 0.68 10.0 0.0 3.0 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Anticodon_1 PF08264.13 CCU98648.1 - 0.11 12.5 0.2 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA HEAT PF02985.22 CCU98648.1 - 2.4 8.6 12.9 4.4 7.8 0.1 5.4 6 0 0 6 6 6 0 HEAT repeat Sec63 PF02889.16 CCU98650.1 - 5.1e-145 481.4 0.0 8.8e-77 257.7 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CCU98650.1 - 3.6e-45 153.9 0.0 4.4e-26 91.7 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CCU98650.1 - 3e-36 124.0 1.5 3e-36 124.0 1.5 2.0 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 CCU98650.1 - 2.1e-24 86.4 0.0 7.5e-16 58.6 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCU98650.1 - 3.9e-11 43.3 0.0 1.4e-07 31.8 0.0 3.4 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CCU98650.1 - 1e-06 29.1 0.1 0.11 12.7 0.1 3.5 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 CCU98650.1 - 0.013 15.9 0.1 7.4 7.0 0.3 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DJ-1_PfpI PF01965.24 CCU98651.1 - 5.6e-28 97.8 0.0 6.2e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family SNO PF01174.19 CCU98651.1 - 0.00064 19.6 0.0 0.00081 19.3 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 CCU98651.1 - 0.0038 16.8 0.1 0.005 16.5 0.1 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Catalase_C PF18011.1 CCU98651.1 - 0.004 16.8 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases GATase PF00117.28 CCU98651.1 - 0.022 14.5 0.1 0.042 13.6 0.1 1.4 2 0 0 2 2 2 0 Glutamine amidotransferase class-I AMP-binding PF00501.28 CCU98652.1 - 6.5e-83 278.7 0.0 5.6e-81 272.3 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCU98652.1 - 0.038 14.9 0.0 0.17 12.9 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain ELYS PF13934.6 CCU98653.1 - 4.8e-30 105.2 1.1 8.7e-30 104.3 1.1 1.4 1 0 0 1 1 1 1 Nuclear pore complex assembly HMG-CoA_red PF00368.18 CCU98654.1 - 3.3e-142 473.9 1.8 4.4e-142 473.4 1.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 CCU98654.1 - 3.1e-11 43.3 2.6 7.2e-07 29.2 0.2 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CCU98654.1 - 0.33 9.0 0.8 0.89 7.5 0.8 1.5 1 1 0 1 1 1 0 Patched family CLU PF13236.6 CCU98655.1 - 4.9e-70 235.8 0.0 9e-70 234.9 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CCU98655.1 - 1.2e-44 152.5 0.0 2.4e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 CCU98655.1 - 7e-23 80.7 9.7 7.2e-10 39.0 0.8 4.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 CCU98655.1 - 1.3e-17 63.1 7.2 1.4e-07 31.1 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.6 CCU98655.1 - 1.1e-07 32.1 0.0 2.2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_2 PF07719.17 CCU98655.1 - 0.026 14.6 0.5 14 6.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF727 PF05303.12 CCU98655.1 - 0.074 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF727) DUF874 PF05917.11 CCU98655.1 - 0.43 9.6 3.7 4 6.4 5.2 1.7 2 0 0 2 2 2 0 Helicobacter pylori protein of unknown function (DUF874) TraV PF09676.10 CCU98655.1 - 1.4 9.9 6.6 0.2 12.7 0.5 2.6 2 1 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Vps36_ESCRT-II PF11605.8 CCU98656.1 - 6.9e-18 64.6 0.0 1.2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 CCU98656.1 - 0.0004 19.6 3.6 0.0004 19.6 3.6 2.6 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DUF2459 PF09601.10 CCU98656.1 - 0.0058 16.4 0.0 0.0096 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2459) zf-CHY PF05495.12 CCU98656.1 - 0.4 11.2 8.1 0.72 10.4 8.1 1.4 1 0 0 1 1 1 0 CHY zinc finger DZR PF12773.7 CCU98656.1 - 0.57 10.2 10.4 30 4.7 10.4 2.4 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_2 PF14445.6 CCU98656.1 - 1.5 9.1 7.0 1 9.6 5.1 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 Methyltransf_23 PF13489.6 CCU98657.1 - 1.1e-21 77.4 0.0 1.8e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCU98657.1 - 9e-21 74.3 0.1 2.2e-20 73.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCU98657.1 - 1.5e-15 57.6 0.5 5.6e-15 55.8 0.2 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCU98657.1 - 3.7e-13 50.1 0.0 8.1e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCU98657.1 - 8.5e-12 45.1 0.0 2.6e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CCU98657.1 - 6.2e-08 32.3 0.1 8e-07 28.6 0.1 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 CCU98657.1 - 3.6e-06 26.5 0.0 5.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 CCU98657.1 - 4.2e-06 26.4 0.0 6.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CCU98657.1 - 0.0012 18.5 0.1 0.0025 17.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 CCU98657.1 - 0.0056 15.6 0.1 0.024 13.6 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) ADH_zinc_N PF00107.26 CCU98657.1 - 0.014 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_32 PF13679.6 CCU98657.1 - 0.022 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 CCU98657.1 - 0.058 13.1 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) NodS PF05401.11 CCU98657.1 - 0.12 11.9 0.1 1.3 8.5 0.1 2.0 2 0 0 2 2 2 0 Nodulation protein S (NodS) Gaa1 PF04114.14 CCU98658.1 - 2e-68 231.7 0.0 1.3e-67 228.9 0.0 1.9 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component WD40 PF00400.32 CCU98659.1 - 3.7e-41 138.3 20.4 4.1e-08 33.8 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU98659.1 - 1.2e-22 80.0 4.4 1.8e-05 25.0 0.1 6.1 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCU98659.1 - 5.7e-09 36.1 0.0 0.00072 19.5 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCU98659.1 - 0.00097 18.2 0.1 0.28 10.1 0.1 3.0 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 CCU98659.1 - 0.097 10.6 0.7 2.7 5.9 0.1 2.7 1 1 1 3 3 3 0 IKI3 family Coatomer_WDAD PF04053.14 CCU98659.1 - 0.1 11.6 0.0 0.39 9.7 0.0 1.9 1 1 0 1 1 1 0 Coatomer WD associated region WD40_like PF17005.5 CCU98659.1 - 0.18 11.1 0.0 5.7 6.2 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain PH PF00169.29 CCU98660.1 - 6.7e-06 26.6 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 PH domain CENP-B_dimeris PF09026.10 CCU98660.1 - 0.073 13.5 3.6 0.15 12.5 3.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 CCU98660.1 - 0.15 12.4 2.3 0.37 11.2 2.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.19 CCU98660.1 - 1.6 9.4 8.9 0.18 12.4 1.2 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Lactamase_B_4 PF13691.6 CCU98661.1 - 5.8e-17 61.1 0.0 1.6e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CCU98661.1 - 2.2e-13 50.2 9.0 1.3e-11 44.4 2.3 3.7 3 1 0 3 3 3 2 Beta-lactamase superfamily domain RNase_P_Rpp14 PF01900.19 CCU98661.1 - 0.021 15.1 0.0 0.061 13.6 0.0 1.8 2 0 0 2 2 2 0 Rpp14/Pop5 family Lactamase_B PF00753.27 CCU98661.1 - 0.025 14.6 0.1 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Cyt-b5 PF00173.28 CCU98662.1 - 2.6e-20 72.3 0.1 2.6e-20 72.3 0.1 2.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 CCU98662.1 - 3e-12 47.0 29.3 4.7e-12 46.4 23.4 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1772 PF08592.11 CCU98662.1 - 0.0078 16.5 2.3 0.0078 16.5 2.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) DUF373 PF04123.13 CCU98662.1 - 2.7 7.4 4.1 0.92 8.9 1.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DEAD PF00270.29 CCU98663.1 - 7.9e-40 136.5 0.0 1.4e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU98663.1 - 2.8e-25 88.8 0.0 1.2e-22 80.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU98663.1 - 3e-10 40.3 0.0 3.5e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CCU98663.1 - 0.0037 17.6 0.0 0.017 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CCU98663.1 - 0.0045 16.3 0.1 0.41 9.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 CCU98663.1 - 0.077 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 CCU98663.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain PHC2_SAM_assoc PF16616.5 CCU98663.1 - 0.15 12.9 7.4 0.36 11.7 7.4 1.6 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 AAA_22 PF13401.6 CCU98663.1 - 0.3 11.3 7.2 0.83 9.9 0.8 3.6 3 1 0 3 3 3 0 AAA domain DnaJ PF00226.31 CCU98664.1 - 7.1e-16 58.1 2.0 1.1e-15 57.5 1.3 1.7 2 0 0 2 2 2 1 DnaJ domain TRAM_LAG1_CLN8 PF03798.16 CCU98665.1 - 2.7e-22 79.5 8.0 2.7e-22 79.5 8.0 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CCU98665.1 - 3.2e-18 65.2 0.6 1.2e-17 63.3 0.6 2.0 1 1 0 1 1 1 1 TRAM1-like protein Acetyltransf_7 PF13508.7 CCU98666.1 - 1.3e-09 38.4 0.0 4.1e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CCU98666.1 - 6.8e-07 29.5 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCU98666.1 - 6.5e-06 26.1 0.0 2.1e-05 24.4 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CCU98666.1 - 0.00079 19.5 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 CCU98666.1 - 0.00082 19.3 0.0 0.0076 16.2 0.0 2.2 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase Mss4 PF04421.13 CCU98666.1 - 0.01 15.9 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Mss4 protein Acetyltransf_9 PF13527.7 CCU98666.1 - 0.016 15.3 0.0 0.051 13.7 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CCU98666.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase FR47 PF08445.10 CCU98666.1 - 0.091 12.7 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 FR47-like protein Toxin_37 PF11415.8 CCU98666.1 - 0.11 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Antifungal peptide termicin Pro_isomerase PF00160.21 CCU98667.1 - 1.3e-49 168.5 0.1 1.5e-49 168.3 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Actin PF00022.19 CCU98668.1 - 2.8e-52 177.7 0.0 1.6e-51 175.2 0.0 1.8 1 1 0 1 1 1 1 Actin PilM_2 PF11104.8 CCU98668.1 - 0.013 14.5 0.0 0.04 13.0 0.0 1.6 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; MreB_Mbl PF06723.13 CCU98668.1 - 0.018 13.9 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein DUF4350 PF14258.6 CCU98668.1 - 0.067 13.6 0.1 7.5 7.1 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) CHCH PF06747.13 CCU98669.1 - 3e-09 36.8 1.8 4.5e-09 36.2 1.8 1.3 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 CCU98669.1 - 0.0035 17.0 3.4 0.0042 16.8 3.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 CCU98669.1 - 0.0061 16.8 3.2 0.0096 16.2 3.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 CCU98669.1 - 0.047 13.7 3.1 0.091 12.8 3.1 1.5 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF5559 PF17714.1 CCU98669.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5559) COX17 PF05051.13 CCU98669.1 - 0.31 11.4 4.0 3.2 8.2 0.3 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Aminotran_1_2 PF00155.21 CCU98670.1 - 1.4e-42 146.2 0.0 1.8e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DNA_pol3_delta2 PF13177.6 CCU98671.1 - 3.5e-10 39.9 0.8 5.3e-10 39.3 0.8 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CCU98671.1 - 0.0012 19.3 0.3 0.0022 18.4 0.3 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 CCU98671.1 - 0.0032 17.8 0.1 0.034 14.5 0.0 2.3 2 1 0 2 2 2 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 CCU98671.1 - 0.036 13.9 0.1 0.053 13.3 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_22 PF13401.6 CCU98671.1 - 0.15 12.3 0.5 0.34 11.2 0.5 1.8 1 1 0 1 1 1 0 AAA domain Peptidase_S9 PF00326.21 CCU98672.1 - 9.2e-54 182.1 0.2 1.5e-53 181.4 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CCU98672.1 - 4.3e-05 22.9 0.3 0.007 15.7 0.3 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 CCU98672.1 - 0.00027 20.7 0.1 0.00049 19.8 0.1 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.12 CCU98672.1 - 0.0038 15.9 0.8 0.2 10.3 0.1 2.5 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 CCU98672.1 - 0.023 14.2 0.0 0.058 12.9 0.0 1.6 2 1 0 2 2 2 0 Esterase PHB depolymerase DLH PF01738.18 CCU98672.1 - 0.032 13.8 0.0 0.097 12.2 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 CCU98672.1 - 0.036 13.9 0.0 0.083 12.7 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 CCU98672.1 - 0.081 11.8 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family Proteasome PF00227.26 CCU98673.1 - 5e-20 71.8 0.0 7e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Nsp1_C PF05064.13 CCU98674.1 - 7.8e-30 103.1 0.4 1.5e-29 102.1 0.4 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 CCU98674.1 - 3.6e-07 31.0 151.3 0.00021 22.1 24.2 6.7 1 1 4 5 5 5 3 Nucleoporin FG repeat region Nucleoporin_FG2 PF15967.5 CCU98674.1 - 2.3e-05 23.1 96.9 0.0082 14.7 1.2 6.2 1 1 6 7 7 7 6 Nucleoporin FG repeated region LTXXQ PF07813.12 CCU98674.1 - 0.0025 18.5 2.8 0.0062 17.2 2.8 1.7 1 0 0 1 1 1 1 LTXXQ motif family protein DUF4407 PF14362.6 CCU98674.1 - 0.021 14.2 1.5 0.03 13.7 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 CCU98674.1 - 0.12 11.0 0.3 0.16 10.6 0.3 1.1 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.8 CCU98674.1 - 0.22 11.7 1.6 24 5.2 0.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Osmo_CC PF08946.10 CCU98674.1 - 0.28 11.4 1.1 0.57 10.5 1.1 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil CC2-LZ PF16516.5 CCU98674.1 - 0.33 11.3 1.7 2.1 8.8 0.6 2.1 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Aa_trans PF01490.18 CCU98675.1 - 1.1e-53 182.4 14.9 1.4e-53 182.1 14.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pex14_N PF04695.13 CCU98675.1 - 0.14 12.8 2.6 0.16 12.6 0.7 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HhH-GPD PF00730.25 CCU98676.1 - 6.3e-13 49.1 0.0 1.5e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RPN1_RPN2_N PF17781.1 CCU98677.1 - 2.7e-113 378.5 0.7 4.4e-113 377.7 0.7 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CCU98677.1 - 7.3e-17 61.2 0.1 1.4e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CCU98677.1 - 1e-14 54.1 11.4 3.9e-05 23.9 0.0 8.0 8 0 0 8 8 8 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CCU98677.1 - 0.00019 21.8 3.0 0.66 10.4 0.0 5.3 4 2 2 6 6 6 2 HEAT repeats RNA_pol_Rbc25 PF08292.12 CCU98682.1 - 1.8e-34 118.7 0.0 2.9e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CCU98682.1 - 6.4e-15 55.3 0.0 1.3e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 SNF2_N PF00176.23 CCU98683.1 - 0.003 16.3 0.2 0.0042 15.9 0.2 1.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain CS PF04969.16 CCU98684.1 - 4.1e-12 47.0 0.0 5.8e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF4167 PF13763.6 CCU98684.1 - 0.18 11.9 0.2 0.3 11.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) Ribosomal_S11 PF00411.19 CCU98685.1 - 1.5e-47 160.5 2.1 1.9e-47 160.2 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L38e PF01781.18 CCU98686.1 - 2.6e-32 110.7 1.2 2.9e-32 110.6 1.2 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family FHA PF00498.26 CCU98687.1 - 1.7e-17 63.5 0.0 2.8e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CCU98687.1 - 0.00015 22.0 0.0 0.00042 20.6 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain MAD PF05557.13 CCU98687.1 - 0.14 10.5 1.8 0.21 9.9 0.2 1.8 2 0 0 2 2 2 0 Mitotic checkpoint protein THOC7 PF05615.13 CCU98687.1 - 0.53 10.6 3.3 0.29 11.4 0.2 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 DUF1664 PF07889.12 CCU98687.1 - 1.1 9.3 4.7 0.67 10.0 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TPR_1 PF00515.28 CCU98688.1 - 5.4e-27 92.5 13.0 6e-05 22.7 0.3 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 CCU98688.1 - 1.4e-21 74.8 21.3 0.005 16.8 0.4 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 CCU98688.1 - 1.7e-20 71.4 6.5 2.2e-05 24.3 0.2 7.6 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCU98688.1 - 3.2e-12 45.9 4.7 0.0026 17.4 0.2 5.0 3 1 2 5 5 5 4 TPR repeat TPR_14 PF13428.6 CCU98688.1 - 9.8e-12 44.7 32.3 0.0027 18.4 0.2 10.0 6 2 5 11 11 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 CCU98688.1 - 1.5e-10 40.7 2.3 0.52 10.8 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCU98688.1 - 1.6e-08 34.7 14.8 0.0064 16.7 0.1 5.2 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 ANAPC8 PF04049.13 CCU98688.1 - 2.2e-08 34.3 0.2 9.5e-08 32.2 0.2 1.9 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_12 PF13424.6 CCU98688.1 - 4.3e-08 33.3 26.1 0.00059 20.1 0.6 6.7 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 CCU98688.1 - 3e-07 29.9 12.1 0.002 17.4 0.0 4.8 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 CCU98688.1 - 8.6e-07 28.6 24.1 0.0082 16.1 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 CCU98688.1 - 8.8e-07 29.0 26.6 9.8e-06 25.6 0.6 5.1 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CCU98688.1 - 8.9e-07 29.5 33.4 0.00034 21.2 1.4 7.0 6 1 2 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 CCU98688.1 - 0.00014 22.3 10.1 22 6.0 0.0 7.5 9 0 0 9 9 6 0 Tetratricopeptide repeat ChAPs PF09295.10 CCU98688.1 - 0.00027 20.1 0.1 0.0062 15.6 0.0 2.6 1 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 CCU98688.1 - 0.00051 20.5 28.0 0.14 12.7 0.0 7.4 6 1 2 8 8 8 2 Tetratricopeptide repeat Sulfotransfer_3 PF13469.6 CCU98688.1 - 0.089 13.2 1.9 0.11 12.8 0.2 2.2 2 1 0 2 2 2 0 Sulfotransferase family TPR_3 PF07720.12 CCU98688.1 - 0.092 12.8 10.8 4.8 7.3 0.7 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 CCU98688.1 - 0.24 11.8 7.2 0.039 14.4 1.3 2.9 3 1 0 3 3 3 0 Bacterial transcriptional activator domain Aminotran_3 PF00202.21 CCU98690.1 - 1.9e-43 148.6 0.0 1.5e-21 76.5 0.0 3.2 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 CCU98690.1 - 3.8e-13 49.7 0.0 6.8e-12 45.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain LAL_C2 PF18603.1 CCU98690.1 - 0.25 11.5 3.5 14 5.9 0.3 3.3 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 Mpp10 PF04006.12 CCU98691.1 - 1.1e-109 367.6 36.6 1.9e-109 366.9 36.6 1.2 1 0 0 1 1 1 1 Mpp10 protein DUF5572 PF17733.1 CCU98692.1 - 3.7e-19 68.3 0.6 1e-18 66.9 0.6 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Gcd10p PF04189.13 CCU98693.1 - 1.1e-68 231.6 0.0 1.4e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family PLDc_2 PF13091.6 CCU98695.1 - 4.8e-12 45.9 0.0 8e-07 29.0 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CCU98695.1 - 2e-06 27.7 3.0 0.053 13.7 0.2 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif Peptidase_M76 PF09768.9 CCU98698.1 - 2.1e-69 232.7 0.2 2.6e-69 232.4 0.2 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 CCU98698.1 - 0.0045 16.8 1.1 0.0045 16.8 1.1 1.8 1 1 1 2 2 2 1 SprT-like family Ribosomal_L13e PF01294.18 CCU98699.1 - 1.2e-71 240.3 7.5 1.2e-71 240.3 7.5 1.4 2 0 0 2 2 2 1 Ribosomal protein L13e EVE PF01878.18 CCU98700.1 - 2.5e-34 118.4 0.1 6.8e-34 117.0 0.1 1.6 1 1 0 1 1 1 1 EVE domain OPT PF03169.15 CCU98702.1 - 2.8e-59 201.3 20.9 3.2e-59 201.1 20.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2427 PF10348.9 CCU98702.1 - 0.18 11.6 4.0 0.15 11.9 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Metallophos PF00149.28 CCU98703.1 - 2.3e-09 38.1 2.0 3.4e-09 37.5 2.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_Phos_2 PF00328.22 CCU98704.1 - 1.2e-05 24.8 0.0 0.0012 18.3 0.0 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) 2-Hacid_dh_C PF02826.19 CCU98705.1 - 6.6e-48 162.4 0.0 9.2e-48 161.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCU98705.1 - 3.9e-19 68.7 0.0 5.1e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CCU98705.1 - 1.5e-05 25.2 0.0 6.6e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CCU98705.1 - 0.0017 17.9 0.0 0.0039 16.8 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_C PF03720.15 CCU98705.1 - 0.0069 16.8 0.0 0.046 14.1 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain MetallophosC PF16370.5 CCU98705.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase WD40 PF00400.32 CCU98706.1 - 5e-29 100.0 11.4 4.5e-07 30.5 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 CCU98706.1 - 3.2e-11 42.6 0.1 0.0022 16.7 0.0 4.2 3 1 1 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CCU98706.1 - 9.3e-06 25.9 0.0 1.1 9.6 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCU98706.1 - 0.18 11.1 0.0 1.8 7.8 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain GET2 PF08690.10 CCU98707.1 - 5.8e-07 29.5 0.0 0.00026 20.8 0.0 2.5 2 1 0 2 2 2 2 GET complex subunit GET2 CAML PF14963.6 CCU98707.1 - 0.088 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DEC-1_N PF04625.13 CCU98707.1 - 0.4 9.6 12.5 0.65 8.9 12.5 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF1631 PF07793.11 CCU98707.1 - 0.94 7.8 8.5 1.3 7.3 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DNA_topoisoIV PF00521.20 CCU98708.1 - 9.6e-124 413.5 0.0 1.5e-123 412.9 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CCU98708.1 - 1.8e-51 173.8 0.1 4.9e-51 172.3 0.1 1.8 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CCU98708.1 - 6.6e-25 87.6 0.3 1.3e-24 86.6 0.3 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CCU98708.1 - 8.2e-14 52.1 0.0 2.1e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CCU98708.1 - 2.8e-06 27.5 0.0 8.4e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Toprim domain ECH_1 PF00378.20 CCU98709.1 - 2.9e-85 285.6 1.5 3.4e-85 285.4 1.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CCU98709.1 - 3.2e-38 132.1 2.1 2.3e-34 119.4 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CCU98709.1 - 0.00015 21.7 0.6 0.026 14.5 0.0 2.7 2 1 1 3 3 3 2 Peptidase family S49 RRM_1 PF00076.22 CCU98710.1 - 0.016 15.0 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1902 PF08972.11 CCU98710.1 - 0.24 11.4 1.2 0.57 10.2 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Phosphodiest PF01663.22 CCU98711.1 - 3.8e-11 43.2 0.1 7.6e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CCU98711.1 - 3.9e-05 23.2 0.1 6.4e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CCU98711.1 - 0.06 12.7 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Sulfatase Gly-zipper_YMGG PF13441.6 CCU98711.1 - 0.84 9.4 13.9 4.4 7.1 13.9 2.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 CCU98711.1 - 0.98 9.5 13.5 5.2 7.2 13.5 2.3 1 0 0 1 1 1 0 Glycine zipper PCI PF01399.27 CCU98712.1 - 0.005 17.3 0.0 0.0087 16.6 0.0 1.4 1 0 0 1 1 1 1 PCI domain DNA_pol_E_B PF04042.16 CCU98713.1 - 7.1e-33 113.7 0.0 9.8e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CCU98713.1 - 5.8e-32 110.5 0.0 8.1e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Dus PF01207.17 CCU98714.1 - 4.2e-50 170.6 0.0 4.5e-35 121.2 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 CCU98714.1 - 3.1e-06 26.9 7.8 0.0013 18.6 2.3 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CCU98714.1 - 3.2e-05 23.6 8.4 0.0021 17.8 0.3 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CCU98714.1 - 0.00013 21.9 12.0 0.0012 18.9 2.3 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 CCU98714.1 - 0.00016 22.4 1.7 0.15 12.8 0.1 2.4 2 0 0 2 2 2 2 Torus domain tRNA-synt_1g PF09334.11 CCU98715.1 - 3e-151 503.6 0.0 3.7e-151 503.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 CCU98715.1 - 9.9e-10 38.4 4.1 2.5e-09 37.2 4.1 1.6 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 CCU98715.1 - 1.6e-07 30.0 1.9 0.00019 19.8 0.0 2.8 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) zinc-ribbons_6 PF07191.12 CCU98715.1 - 0.16 12.0 7.8 0.65 10.0 7.7 2.0 1 1 1 2 2 2 0 zinc-ribbons HypA PF01155.19 CCU98715.1 - 0.53 10.3 6.2 2.1 8.4 0.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CCU98715.1 - 0.61 10.1 10.8 0.42 10.7 6.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 CCU98715.1 - 2.1 8.3 8.1 1.9 8.4 1.5 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 CCU98715.1 - 4.9 7.3 9.4 6.6 6.9 2.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain cNMP_binding PF00027.29 CCU98716.1 - 4.4e-27 94.0 0.1 1.5e-14 53.8 0.0 4.5 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.22 CCU98716.1 - 8.6e-17 62.0 9.3 9.4e-11 42.3 6.0 3.0 3 0 0 3 3 3 2 Patatin-like phospholipase Gln-synt_C PF00120.24 CCU98717.1 - 2.9e-15 56.1 0.0 2.8e-12 46.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CCU98717.1 - 1.5e-13 50.3 0.0 2.4e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain FAD_binding_2 PF00890.24 CCU98717.1 - 0.0041 16.2 0.1 0.007 15.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain SMK-1 PF04802.15 CCU98718.1 - 2.7e-61 206.8 0.2 4.1e-61 206.1 0.2 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Arm_2 PF04826.13 CCU98718.1 - 0.0065 16.0 0.1 0.17 11.3 0.1 2.2 2 0 0 2 2 2 1 Armadillo-like RICTOR_N PF14664.6 CCU98718.1 - 0.0075 15.3 0.8 0.013 14.5 0.8 1.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term Rcd1 PF04078.13 CCU98718.1 - 0.05 12.9 1.7 0.21 10.8 0.4 2.3 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like YEATS PF03366.16 CCU98719.1 - 5.6e-39 132.0 0.0 8.1e-39 131.5 0.0 1.2 1 0 0 1 1 1 1 YEATS family PPR_2 PF13041.6 CCU98720.1 - 1.9e-19 69.6 0.0 6.2e-07 29.5 0.0 5.8 6 1 0 6 6 6 2 PPR repeat family PPR PF01535.20 CCU98720.1 - 4.1e-15 54.9 0.0 0.017 15.3 0.0 9.4 9 0 0 9 9 9 2 PPR repeat PPR_3 PF13812.6 CCU98720.1 - 1.2e-09 38.1 0.0 0.034 14.2 0.0 5.4 4 1 2 6 6 6 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 CCU98720.1 - 4.4e-09 35.9 0.0 0.011 15.5 0.0 5.0 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 CCU98720.1 - 1.7e-07 30.8 6.6 0.00077 18.9 0.4 5.2 5 1 1 6 6 6 2 Pentacotripeptide-repeat region of PRORP TPR_2 PF07719.17 CCU98720.1 - 0.32 11.2 5.7 43 4.6 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCU98720.1 - 0.75 10.6 3.5 33 5.4 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DLIC PF05783.11 CCU98721.1 - 1.2e-19 70.5 0.0 1.4e-13 50.5 0.0 2.9 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 CCU98721.1 - 7.6e-05 23.2 0.9 0.00025 21.5 0.9 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CCU98721.1 - 0.0028 17.8 4.8 0.0056 16.9 0.3 3.4 3 1 1 4 4 4 1 AAA domain AAA_22 PF13401.6 CCU98721.1 - 0.0051 17.1 0.0 0.016 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CCU98721.1 - 0.0077 16.2 0.1 0.023 14.6 0.0 1.9 1 1 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 CCU98721.1 - 0.011 16.2 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 CCU98721.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCU98721.1 - 0.02 14.8 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 CCU98721.1 - 0.028 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 CCU98721.1 - 0.033 14.0 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CCU98721.1 - 0.037 13.3 0.1 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 CCU98721.1 - 0.041 14.3 0.0 0.076 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 CCU98721.1 - 0.067 12.8 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 CCU98721.1 - 0.078 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 CCU98721.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 CCU98721.1 - 0.092 13.3 0.0 0.25 11.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 CCU98721.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 CCU98721.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.5 1 1 0 1 1 1 0 NTPase AAA_24 PF13479.6 CCU98721.1 - 0.22 11.2 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 CCU98721.1 - 0.25 10.7 0.0 2.5 7.5 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SAC3_GANP PF03399.16 CCU98722.1 - 1.9e-97 326.2 0.0 6.8e-97 324.4 0.0 1.8 2 0 0 2 2 2 1 SAC3/GANP family Voltage_CLC PF00654.20 CCU98722.1 - 3.3e-78 263.4 29.1 5.1e-77 259.5 29.1 2.2 1 1 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 CCU98722.1 - 8.4e-05 22.9 0.3 0.0056 17.1 0.1 3.2 3 0 0 3 3 3 1 CBS domain CSN8_PSD8_EIF3K PF10075.9 CCU98722.1 - 0.17 11.8 0.0 0.98 9.4 0.0 2.1 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family FolB PF02152.18 CCU98722.1 - 0.22 12.1 0.3 0.5 10.9 0.3 1.5 1 0 0 1 1 1 0 Dihydroneopterin aldolase CHD5 PF04420.14 CCU98724.1 - 1.1e-16 61.1 12.5 4.7e-13 49.3 3.7 2.1 1 1 1 2 2 2 2 CHD5-like protein EMC3_TMCO1 PF01956.16 CCU98724.1 - 0.02 14.6 0.2 0.025 14.3 0.2 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Ribosomal_L29 PF00831.23 CCU98724.1 - 0.023 14.7 0.3 0.041 13.9 0.3 1.3 1 0 0 1 1 1 0 Ribosomal L29 protein Pannexin_like PF12534.8 CCU98724.1 - 0.11 11.6 0.2 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DASH_Hsk3 PF08227.11 CCU98724.1 - 0.26 11.7 1.1 0.8 10.1 0.4 1.9 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like SCP2 PF02036.17 CCU98725.1 - 2.3e-05 24.8 0.0 3.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CCU98725.1 - 0.0048 17.2 0.0 0.0066 16.7 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal TPR_MLP1_2 PF07926.12 CCU98726.1 - 1.2e-08 35.0 29.1 1.2e-08 35.0 29.1 15.6 9 5 5 14 14 14 5 TPR/MLP1/MLP2-like protein DUF1492 PF07374.11 CCU98726.1 - 1.3 9.2 4.8 4.3 7.5 0.1 4.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1492) ThiF PF00899.21 CCU98728.1 - 1.9e-24 86.4 0.0 2.4e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family DHHC PF01529.20 CCU98729.1 - 3e-29 101.8 6.2 6.6e-29 100.7 6.2 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF1069 PF06370.11 CCU98729.1 - 0.019 14.5 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) GT87 PF09594.10 CCU98729.1 - 0.14 11.9 9.3 0.074 12.7 0.7 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 87 AAA_23 PF13476.6 CCU98730.1 - 9.6e-30 104.6 0.0 9.6e-30 104.6 0.0 4.6 4 2 0 5 5 5 1 AAA domain SMC_N PF02463.19 CCU98730.1 - 8.8e-13 48.2 0.0 3.7e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CCU98730.1 - 1.6e-06 28.1 0.0 0.001 18.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CCU98730.1 - 1.1e-05 25.3 0.0 3.5e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain DUF3584 PF12128.8 CCU98730.1 - 0.00028 18.6 14.8 0.00028 18.6 14.8 6.1 3 2 1 6 6 6 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 CCU98730.1 - 0.0067 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CCU98730.1 - 0.03 14.8 0.0 0.03 14.8 0.0 5.2 6 2 0 6 6 6 0 ABC transporter GTP_EFTU PF00009.27 CCU98730.1 - 0.15 11.6 5.0 1.4 8.4 0.1 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CCU98730.1 - 0.37 11.1 0.0 0.37 11.1 0.0 3.1 2 1 1 3 3 3 0 AAA domain V-SNARE_C PF12352.8 CCU98730.1 - 3.2 8.1 8.5 17 5.8 0.1 4.1 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Ish1 PF10281.9 CCU98731.1 - 3.7e-54 180.7 19.9 1.3e-11 44.6 1.0 6.6 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein HeH PF12949.7 CCU98731.1 - 4e-07 29.6 0.6 0.1 12.3 0.1 5.6 6 0 0 6 6 6 1 HeH/LEM domain SAP PF02037.27 CCU98731.1 - 0.0022 17.7 0.0 1.2 8.9 0.0 4.0 4 0 0 4 4 4 1 SAP domain Apolipoprotein PF01442.18 CCU98731.1 - 0.035 14.0 3.9 0.1 12.5 1.7 2.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Slx4 PF09494.10 CCU98731.1 - 0.056 13.4 1.9 64 3.6 0.0 4.3 5 1 0 5 5 5 0 Slx4 endonuclease Phasin_2 PF09361.10 CCU98731.1 - 0.14 12.5 17.3 0.24 11.7 11.1 3.1 3 0 0 3 3 3 0 Phasin protein ADIP PF11559.8 CCU98731.1 - 0.2 11.8 0.4 11 6.0 0.0 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding SAM_2 PF07647.17 CCU98731.1 - 0.82 9.8 2.7 17 5.6 0.1 3.3 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) YtxH PF12732.7 CCU98731.1 - 8.8 6.9 9.4 62 4.2 0.1 3.9 2 2 0 2 2 2 0 YtxH-like protein F-box-like PF12937.7 CCU98733.1 - 6.1e-14 51.6 2.2 2.1e-13 49.9 2.2 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CCU98733.1 - 2.8e-09 36.6 0.3 9.5e-09 34.9 0.3 2.0 1 0 0 1 1 1 1 F-box domain SAP30_Sin3_bdg PF13867.6 CCU98733.1 - 0.0036 17.6 0.3 0.0075 16.6 0.3 1.6 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 XPG_I PF00867.18 CCU98734.1 - 4.9e-09 36.4 0.2 1.7e-08 34.7 0.2 2.0 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CCU98734.1 - 4e-06 27.2 0.0 1e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain BP28CT PF08146.12 CCU98735.1 - 4.8e-24 85.0 0.0 1.3e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 CCU98735.1 - 1.2e-09 38.5 0.1 1.2e-09 38.5 0.1 4.5 5 1 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 FliG_M PF14841.6 CCU98735.1 - 0.012 15.8 1.2 0.068 13.4 1.2 2.4 1 0 0 1 1 1 0 FliG middle domain PHD PF00628.29 CCU98736.1 - 2e-06 27.6 19.7 3.3e-06 26.9 19.7 1.4 1 0 0 1 1 1 1 PHD-finger PQQ PF01011.21 CCU98737.1 - 3.9e-08 32.9 0.0 0.012 15.5 0.0 3.1 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 CCU98737.1 - 0.00045 19.9 0.0 0.51 9.9 0.0 2.5 2 0 0 2 2 2 2 PQQ-like domain ANAPC4_WD40 PF12894.7 CCU98737.1 - 0.0012 19.1 0.0 1.1 9.6 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Neuraminidase PF18413.1 CCU98737.1 - 0.33 10.6 2.0 3.1 7.4 0.1 2.2 2 0 0 2 2 2 0 Neuraminidase-like domain Lactamase_B_6 PF16661.5 CCU98738.1 - 3e-48 163.8 0.0 1.1e-47 161.9 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CCU98738.1 - 1.8e-26 93.3 0.1 3.9e-21 76.0 0.0 3.2 2 1 1 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 CCU98738.1 - 3.4e-17 62.7 0.0 7.8e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 CCU98738.1 - 3.4e-05 23.7 0.0 0.00016 21.6 0.0 2.2 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 CCU98738.1 - 0.073 12.6 0.2 0.18 11.3 0.2 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ribosomal_L3 PF00297.22 CCU98739.1 - 5.3e-22 78.3 1.3 9.6e-19 67.6 0.3 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 DSPc PF00782.20 CCU98740.1 - 6.3e-31 106.9 0.0 4.9e-23 81.4 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCU98740.1 - 0.033 13.7 0.0 0.095 12.3 0.0 1.6 2 0 0 2 2 2 0 Protein-tyrosine phosphatase F-box PF00646.33 CCU98741.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 F-box domain Cpn60_TCP1 PF00118.24 CCU98742.1 - 6.7e-153 509.9 4.9 7.7e-153 509.7 4.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GSK-3_bind PF05350.12 CCU98742.1 - 0.083 12.2 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding G_glu_transpept PF01019.21 CCU98743.1 - 8.1e-142 473.6 0.0 9.3e-142 473.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Spc7 PF08317.11 CCU98744.1 - 8.8e-05 21.5 24.6 0.0038 16.2 0.5 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein Lebercilin PF15619.6 CCU98744.1 - 0.0026 17.5 26.7 0.27 10.8 21.6 2.3 2 0 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 CCU98744.1 - 0.011 16.0 9.0 0.91 9.7 3.8 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Filament PF00038.21 CCU98744.1 - 0.055 13.0 22.6 0.21 11.1 14.6 2.2 2 0 0 2 2 2 0 Intermediate filament protein Golgin_A5 PF09787.9 CCU98744.1 - 0.059 12.8 25.0 0.9 9.0 16.2 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 FapA PF03961.13 CCU98744.1 - 0.24 9.9 8.9 0.37 9.3 2.4 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF4482 PF14818.6 CCU98744.1 - 0.29 12.0 20.9 0.3 12.0 8.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) Swi5 PF07061.11 CCU98744.1 - 0.38 10.9 21.8 0.62 10.2 3.4 3.6 2 1 1 3 3 3 0 Swi5 DUF641 PF04859.12 CCU98744.1 - 0.6 10.4 19.8 1.3 9.3 0.1 3.4 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) LMBR1 PF04791.16 CCU98744.1 - 0.81 8.5 2.7 3.5 6.4 0.0 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 CCU98744.1 - 0.84 9.1 14.6 0.86 9.1 9.5 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF1043 PF06295.12 CCU98744.1 - 0.97 9.4 12.2 0.13 12.3 2.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) DHR10 PF18595.1 CCU98744.1 - 1.4 9.0 37.1 1.6 8.8 24.2 2.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain YlqD PF11068.8 CCU98744.1 - 1.8 9.0 17.9 0.1 12.9 8.7 2.4 2 0 0 2 2 2 0 YlqD protein UPF0242 PF06785.11 CCU98744.1 - 1.9 8.6 26.8 0.8 9.8 18.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MscS_porin PF12795.7 CCU98744.1 - 2.2 7.8 45.0 0.019 14.5 2.8 3.5 2 2 1 3 3 3 0 Mechanosensitive ion channel porin domain DUF724 PF05266.14 CCU98744.1 - 3.7 7.3 22.9 2.6 7.8 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 CCU98744.1 - 8.1 5.7 27.8 3.4 6.9 3.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 CCU98744.1 - 9.6 5.2 19.9 8.8 5.3 12.9 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NGP1NT PF08153.12 CCU98745.1 - 2.1e-47 160.5 1.8 2.3e-47 160.4 0.0 1.9 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CCU98745.1 - 3.2e-18 65.9 0.0 6.8e-15 55.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CCU98745.1 - 1.2e-06 28.1 0.2 6.6e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CCU98745.1 - 0.00044 20.2 0.0 0.001 19.0 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 CCU98745.1 - 0.00078 18.9 0.1 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF2457 PF10446.9 CCU98745.1 - 0.0013 18.0 39.6 0.0021 17.3 39.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) GTP_EFTU PF00009.27 CCU98745.1 - 0.011 15.3 0.1 0.55 9.7 0.0 2.8 1 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Nop14 PF04147.12 CCU98745.1 - 0.031 12.5 34.2 0.043 12.0 34.2 1.1 1 0 0 1 1 1 0 Nop14-like family Roc PF08477.13 CCU98745.1 - 0.078 13.2 0.0 7.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SDA1 PF05285.12 CCU98745.1 - 0.14 11.5 34.4 0.36 10.2 34.4 1.7 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CCU98745.1 - 0.21 9.9 30.5 0.34 9.2 30.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CCU98745.1 - 0.38 8.8 42.2 0.57 8.2 42.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 CCU98745.1 - 0.39 10.0 33.6 0.61 9.4 33.6 1.3 1 0 0 1 1 1 0 BUD22 SpoIIIAH PF12685.7 CCU98745.1 - 1.2 9.0 14.7 2.3 8.0 14.7 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop53 PF07767.11 CCU98745.1 - 6.8 6.0 31.8 13 5.0 31.8 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) tRNA-synt_1d PF00750.19 CCU98746.1 - 7.1e-101 337.6 0.1 9.5e-101 337.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CCU98746.1 - 7.6e-19 68.0 0.0 1.8e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain POT1 PF02765.17 CCU98746.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 Leu_zip PF15294.6 CCU98747.1 - 0.00038 20.1 4.7 0.00038 20.1 4.7 1.9 1 1 1 2 2 2 1 Leucine zipper ATG16 PF08614.11 CCU98747.1 - 0.0025 18.1 5.3 0.0025 18.1 5.3 3.4 2 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Lzipper-MIP1 PF14389.6 CCU98747.1 - 0.037 14.3 0.2 0.037 14.3 0.2 3.6 4 0 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 Chibby PF14645.6 CCU98747.1 - 0.43 11.0 5.6 0.17 12.3 0.6 2.4 1 1 0 2 2 2 0 Chibby family OmpH PF03938.14 CCU98747.1 - 0.61 10.4 18.0 1.1 9.6 1.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF724 PF05266.14 CCU98747.1 - 1.6 8.5 10.1 3.5 7.4 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 CCU98747.1 - 2.5 7.4 19.2 5 6.4 7.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 CCU98747.1 - 6.3 7.0 12.0 19 5.5 2.4 3.3 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 CCU98747.1 - 7.3 5.4 18.5 1.2 7.9 2.1 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF572 PF04502.13 CCU98747.1 - 9.4 5.7 6.3 19 4.7 6.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) VHS PF00790.19 CCU98749.1 - 7.4e-37 126.3 0.0 7.3e-36 123.1 0.0 2.3 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 CCU98749.1 - 1.3e-17 63.9 0.2 6.4e-17 61.6 0.0 2.3 2 0 0 2 2 2 1 GAT domain DUF2890 PF11081.8 CCU98749.1 - 0.094 12.8 2.1 0.25 11.5 2.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) GGA_N-GAT PF18308.1 CCU98749.1 - 1.2 8.9 4.3 0.57 9.8 0.4 2.5 3 0 0 3 3 3 0 GGA N-GAT domain FUSC PF04632.12 CCU98749.1 - 3.5 6.0 7.9 6.5 5.2 7.9 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family PPR_2 PF13041.6 CCU98750.1 - 1.1e-08 35.1 0.0 0.53 10.5 0.0 5.1 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.6 CCU98750.1 - 2.2e-05 24.4 0.0 1.3 9.1 0.0 4.1 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 CCU98750.1 - 0.00012 21.6 0.4 0.022 14.4 0.0 3.6 3 1 0 3 3 3 1 PPR repeat PPR PF01535.20 CCU98750.1 - 0.00042 20.4 1.9 1.8 9.0 0.0 5.2 5 0 0 5 5 5 1 PPR repeat DUF1569 PF07606.11 CCU98750.1 - 0.072 13.1 0.2 0.072 13.1 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1569) Pox_A_type_inc PF04508.12 CCU98750.1 - 0.2 11.5 2.6 0.5 10.3 2.6 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat PIP5K PF01504.18 CCU98751.1 - 1e-42 146.3 0.1 1.3e-33 116.5 0.1 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 CCU98751.1 - 7.7e-19 67.7 0.1 1.2e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CCU98751.1 - 3.6e-17 62.3 9.5 1.1e-16 60.7 9.5 1.9 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CCU98751.1 - 0.24 11.6 4.0 0.83 9.9 4.0 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger MbeD_MobD PF04899.12 CCU98751.1 - 3.7 7.7 5.0 59 3.9 0.9 3.2 3 0 0 3 3 3 0 MbeD/MobD like AAA PF00004.29 CCU98752.1 - 4e-43 147.0 0.0 6.7e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCU98752.1 - 5.3e-09 35.7 3.3 7.1e-09 35.3 0.2 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CCU98752.1 - 6.8e-09 36.3 0.0 1e-05 26.0 0.1 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CCU98752.1 - 8.2e-08 32.3 0.1 3.5e-07 30.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 CCU98752.1 - 1.5e-06 28.1 0.1 3.9e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CCU98752.1 - 5.4e-06 26.6 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CCU98752.1 - 2.8e-05 24.4 0.1 0.0044 17.3 0.1 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CCU98752.1 - 2.8e-05 23.9 0.0 6.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CCU98752.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 CCU98752.1 - 0.0014 17.8 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CCU98752.1 - 0.0015 19.0 0.0 0.0097 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CCU98752.1 - 0.0027 17.5 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CCU98752.1 - 0.0037 16.7 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CCU98752.1 - 0.0051 16.3 0.0 0.01 15.4 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CCU98752.1 - 0.0063 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 CCU98752.1 - 0.0079 15.9 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.26 CCU98752.1 - 0.008 15.9 0.1 0.033 13.9 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain TsaE PF02367.17 CCU98752.1 - 0.0087 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CCU98752.1 - 0.0088 15.8 0.1 0.023 14.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CCU98752.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CCU98752.1 - 0.012 15.9 0.1 0.029 14.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 CCU98752.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CCU98752.1 - 0.017 15.3 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CCU98752.1 - 0.018 14.5 0.1 0.036 13.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 CCU98752.1 - 0.025 15.1 1.3 8.8 6.8 1.6 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CCU98752.1 - 0.029 13.7 0.1 0.071 12.4 0.0 1.7 2 0 0 2 2 1 0 KaiC AAA_11 PF13086.6 CCU98752.1 - 0.045 13.5 0.5 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CCU98752.1 - 0.046 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Prot_ATP_OB_N PF17758.1 CCU98752.1 - 0.056 13.1 1.1 0.11 12.1 0.3 1.8 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain NACHT PF05729.12 CCU98752.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.7 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 CCU98752.1 - 0.084 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CCU98752.1 - 0.085 12.4 0.7 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain Peptidase_C54 PF03416.19 CCU98752.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C54 ATPase_2 PF01637.18 CCU98752.1 - 0.13 12.1 0.0 0.49 10.3 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CCU98752.1 - 0.13 12.6 1.0 0.27 11.6 0.1 1.8 2 1 0 2 2 1 0 AAA domain Clathrin PF00637.20 CCU98753.1 - 5.3e-199 652.1 27.2 1.7e-30 105.8 0.0 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CCU98753.1 - 8.8e-33 112.0 0.4 1.1e-31 108.5 0.1 3.0 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 CCU98753.1 - 3.6e-28 96.5 0.0 0.00023 21.3 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin-link PF09268.10 CCU98753.1 - 2.2e-11 42.9 0.3 7.9e-11 41.1 0.1 2.2 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 CCU98753.1 - 6.1e-07 28.8 0.3 0.11 11.6 0.0 3.8 3 0 0 3 3 3 2 Coatomer WD associated region TPR_1 PF00515.28 CCU98753.1 - 1.8e-05 24.3 4.3 16 5.5 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCU98753.1 - 0.0045 17.0 8.3 32 5.0 0.0 7.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 CCU98753.1 - 0.025 15.4 18.4 1.1e+02 4.0 0.2 10.4 11 1 1 12 12 10 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCU98753.1 - 0.041 13.9 8.0 13 6.0 0.1 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCU98753.1 - 3 8.3 7.0 1.2e+02 3.3 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCU98753.1 - 3.9 7.8 16.0 4.5 7.6 0.7 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat PX PF00787.24 CCU98754.1 - 2.2e-21 76.0 0.1 5.6e-21 74.7 0.1 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CCU98754.1 - 4.4e-06 26.4 5.2 0.018 14.6 0.5 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 CCU98754.1 - 0.01 15.5 0.3 0.01 15.5 0.3 2.0 2 0 0 2 2 2 0 BAR domain RNA_capsid PF03035.14 CCU98754.1 - 0.051 13.6 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein IATP PF04568.12 CCU98754.1 - 1.2 9.6 4.2 0.42 11.1 0.5 2.1 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Nup54 PF13874.6 CCU98754.1 - 3.2 7.9 7.1 0.3 11.2 1.5 2.1 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Fis1_TPR_N PF14852.6 CCU98755.1 - 7.2e-17 60.8 0.0 1.2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCU98755.1 - 3.8e-10 39.7 0.6 6.4e-10 39.0 0.6 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 CCU98755.1 - 0.013 15.6 0.7 0.034 14.2 0.4 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-NOSIP PF15906.5 CCU98756.1 - 2.2e-10 40.5 0.2 8.3e-10 38.7 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 CCU98756.1 - 9e-08 31.9 21.3 2.6e-05 24.0 9.4 2.6 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCU98756.1 - 2.3e-07 30.7 18.7 0.00052 20.0 1.9 2.5 2 0 0 2 2 2 2 RING-type zinc-finger FYVE PF01363.21 CCU98756.1 - 1.5e-06 28.2 4.9 1.5e-06 28.2 4.9 2.8 3 1 0 3 3 3 1 FYVE zinc finger zf-C3HC4 PF00097.25 CCU98756.1 - 1.6e-05 24.6 23.5 0.0052 16.6 11.2 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCU98756.1 - 2.9e-05 23.8 24.7 0.031 14.1 12.7 3.5 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 Rtf2 PF04641.12 CCU98756.1 - 6.5e-05 22.4 17.5 0.00035 20.0 0.8 3.0 1 1 2 3 3 3 2 Rtf2 RING-finger zf-RING_2 PF13639.6 CCU98756.1 - 8e-05 22.9 21.0 0.0027 18.0 10.3 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 CCU98756.1 - 0.00029 20.6 24.3 0.016 15.1 4.2 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCU98756.1 - 0.00029 20.7 25.8 0.00067 19.6 10.1 3.8 2 2 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CCU98756.1 - 0.00067 19.8 20.0 0.02 15.0 1.2 3.5 3 1 0 3 3 3 2 zinc finger of C3HC4-type, RING ETC_C1_NDUFA5 PF04716.14 CCU98757.1 - 6.1e-19 67.6 0.1 9.6e-19 67.0 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Sds3 PF08598.11 CCU98758.1 - 1e-08 35.5 0.2 1.4e-08 35.0 0.2 1.2 1 0 0 1 1 1 1 Sds3-like Sacchrp_dh_C PF16653.5 CCU98758.1 - 0.035 14.2 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase C-terminal domain Decorin_bind PF02352.15 CCU98758.1 - 0.053 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Decorin binding protein Orn_Arg_deC_N PF02784.16 CCU98759.1 - 2.9e-75 252.8 0.0 4.3e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CCU98759.1 - 2.3e-17 63.0 0.0 2.7e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain B12-binding PF02310.19 CCU98759.1 - 0.19 11.8 0.0 0.81 9.7 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain Zn_clus PF00172.18 CCU98760.1 - 2.3e-05 24.4 7.8 2.3e-05 24.4 7.8 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 CCU98761.1 - 1.4e-62 211.5 0.0 3.4e-62 210.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98761.1 - 6.4e-33 114.1 0.0 1.6e-32 112.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pentapeptide_4 PF13599.6 CCU98761.1 - 0.0028 17.8 0.0 2.7 8.2 0.0 2.9 1 1 3 4 4 4 3 Pentapeptide repeats (9 copies) APH PF01636.23 CCU98761.1 - 0.021 14.8 0.0 0.021 14.8 0.0 3.8 3 1 0 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CCU98761.1 - 0.17 11.5 0.0 0.17 11.5 0.0 3.1 2 1 0 2 2 2 0 Choline/ethanolamine kinase PTPRCAP PF15713.5 CCU98761.1 - 4.3 7.6 0.0 4.3 7.6 0.0 4.3 2 1 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Complex1_LYR PF05347.15 CCU98762.1 - 0.0011 19.0 7.8 0.0093 16.0 7.8 2.2 1 1 0 1 1 1 1 Complex 1 protein (LYR family) UPRTase PF14681.6 CCU98763.1 - 9.3e-50 168.9 0.0 8.8e-26 90.6 0.0 2.1 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Rxt3 PF08642.10 CCU98764.1 - 8.5e-21 75.0 0.0 1.9e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 CCU98764.1 - 0.01 15.9 0.0 0.073 13.2 0.0 2.0 2 0 0 2 2 2 0 LCCL domain ESCRT-II PF05871.12 CCU98765.1 - 9.3e-43 145.8 0.0 1.2e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit WD40 PF00400.32 CCU98766.1 - 1.1e-22 79.9 3.1 4.3e-06 27.4 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU98766.1 - 0.025 14.9 0.2 11 6.4 0.0 3.5 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Trimer_CC PF08954.11 CCU98766.1 - 0.074 12.6 0.7 0.2 11.2 0.7 1.7 1 0 0 1 1 1 0 Trimerisation motif WD40_like PF17005.5 CCU98766.1 - 0.17 11.1 0.0 7.1 5.9 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain TPT PF03151.16 CCU98768.1 - 0.071 12.4 0.3 0.08 12.3 0.3 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family UAA PF08449.11 CCU98769.1 - 0.00054 19.3 9.4 0.0011 18.2 9.4 1.4 1 1 0 1 1 1 1 UAA transporter family NMO PF03060.15 CCU98770.1 - 1.5e-38 133.1 3.4 1.9e-30 106.4 0.3 2.3 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 CCU98770.1 - 8.6e-09 34.8 0.3 0.0012 17.9 0.0 2.8 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CCU98770.1 - 9e-06 24.9 1.1 1.5e-05 24.2 1.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CCU98770.1 - 0.098 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Glu_synthase PF01645.17 CCU98770.1 - 0.18 10.9 1.2 0.43 9.6 1.2 1.5 1 1 0 1 1 1 0 Conserved region in glutamate synthase DUF1729 PF08354.10 CCU98770.1 - 0.18 10.7 0.1 0.4 9.5 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1729) ABC_membrane_2 PF06472.15 CCU98771.1 - 3e-88 295.7 4.9 3.8e-88 295.4 4.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CCU98771.1 - 2.6e-15 57.2 0.0 6.4e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.12 CCU98771.1 - 0.04 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_21 PF13304.6 CCU98771.1 - 0.097 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 CCU98771.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CCU98771.1 - 0.17 12.4 0.0 0.6 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 CCU98773.1 - 1e-10 41.9 0.0 2.2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 CCU98773.1 - 1.4e-06 28.5 0.2 5.1e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 CCU98773.1 - 0.0058 16.5 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase CPT PF07931.12 CCU98773.1 - 0.039 13.8 0.1 0.1 12.5 0.1 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 CCU98773.1 - 0.047 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase Zn_clus PF00172.18 CCU98774.1 - 8.3e-09 35.4 9.1 1.5e-08 34.6 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L23 PF00276.20 CCU98776.1 - 3.1e-05 24.2 0.0 5.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 DUF2057 PF09829.9 CCU98776.1 - 0.68 10.1 3.0 0.29 11.3 0.5 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) NIF PF03031.18 CCU98777.1 - 1.8e-52 177.3 0.0 2.5e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PCC_BT PF18140.1 CCU98777.1 - 0.03 14.7 0.0 0.35 11.2 0.1 2.0 2 0 0 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain Pkinase PF00069.25 CCU98778.1 - 7.6e-54 182.8 0.0 1e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98778.1 - 9.3e-29 100.5 0.0 1.4e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU98778.1 - 4.4e-05 22.9 0.0 7.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF2340 PF10209.9 CCU98779.1 - 1.5e-45 154.5 0.0 1.8e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) PXA PF02194.15 CCU98780.1 - 6.9e-12 45.7 0.1 0.00018 21.6 0.0 2.6 1 1 1 2 2 2 2 PXA domain Nexin_C PF08628.12 CCU98780.1 - 5.9e-11 42.9 0.0 5.5e-10 39.8 0.0 2.6 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 CCU98780.1 - 0.088 12.8 0.0 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 PX domain XPG_N PF00752.17 CCU98781.1 - 1.2e-29 102.7 0.0 2.3e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CCU98781.1 - 2.6e-25 88.6 0.0 5.8e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 CCU98781.1 - 1.3e-06 28.0 0.0 2.3e-05 24.0 0.0 2.6 1 1 0 1 1 1 1 XPG domain containing Sec5 PF15469.6 CCU98781.1 - 0.00017 21.5 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 HHH_5 PF14520.6 CCU98781.1 - 0.0094 16.5 0.0 0.024 15.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF1640 PF07798.11 CCU98781.1 - 1.3 9.1 4.7 3.3 7.7 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) NDUF_B8 PF05821.11 CCU98782.1 - 0.00011 22.1 1.7 0.00015 21.6 1.7 1.4 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Metallophos PF00149.28 CCU98783.1 - 6.3e-37 128.1 0.8 9.3e-37 127.5 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCU98783.1 - 0.00012 22.4 0.2 0.00025 21.4 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 CCU98783.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain MCM PF00493.23 CCU98784.1 - 1.1e-100 335.3 0.0 1.5e-100 334.9 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCU98784.1 - 2.1e-38 131.0 0.0 4.2e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCU98784.1 - 1.3e-25 89.6 1.1 1.3e-25 89.6 1.1 3.2 5 0 0 5 5 5 1 MCM AAA-lid domain MCM2_N PF12619.8 CCU98784.1 - 5.3e-22 78.8 11.3 5.3e-22 78.8 11.3 3.1 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 CCU98784.1 - 1.7e-13 51.0 0.1 6.3e-12 46.0 0.0 2.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCU98784.1 - 3.2e-08 33.2 0.0 9.9e-07 28.3 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCU98784.1 - 4e-06 26.9 0.0 8.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CCU98784.1 - 0.0008 19.3 0.0 0.0054 16.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCU98784.1 - 0.019 14.7 0.0 0.23 11.1 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_lid_2 PF17863.1 CCU98784.1 - 0.051 13.4 0.3 0.25 11.2 0.3 2.2 1 0 0 1 1 1 0 AAA lid domain DNA_gyraseB_C PF00986.21 CCU98784.1 - 0.079 13.2 0.7 4.5 7.5 0.0 2.8 3 0 0 3 3 3 0 DNA gyrase B subunit, carboxyl terminus AAA PF00004.29 CCU98784.1 - 0.11 13.0 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CCU98784.1 - 0.11 12.2 0.3 0.56 9.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain Zn_ribbon_2 PF12674.7 CCU98784.1 - 0.15 12.7 0.2 0.4 11.4 0.2 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain UQ_con PF00179.26 CCU98785.1 - 1.5e-06 27.9 1.9 1.5e-06 27.9 1.9 2.1 2 1 0 2 2 2 1 Ubiquitin-conjugating enzyme Csm1 PF12539.8 CCU98786.1 - 3.3e-15 56.5 0.0 5.6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 TMCO5 PF14992.6 CCU98786.1 - 0.0017 18.0 0.2 0.0018 17.9 0.2 1.2 1 0 0 1 1 1 1 TMCO5 family Cortex-I_coil PF09304.10 CCU98786.1 - 0.022 15.0 3.3 0.022 15.0 3.3 1.9 2 1 0 2 2 2 0 Cortexillin I, coiled coil APG6_N PF17675.1 CCU98786.1 - 0.068 13.7 5.4 0.086 13.4 3.6 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region CSN5_C PF18323.1 CCU98786.1 - 0.092 13.7 0.5 0.23 12.4 0.5 1.7 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain ABC2_membrane PF01061.24 CCU98787.1 - 1e-230 760.2 168.7 5.2e-42 143.6 13.3 7.0 7 0 0 7 7 6 6 ABC-2 type transporter ABC_tran PF00005.27 CCU98787.1 - 7.3e-118 389.3 0.0 6e-18 65.7 0.0 8.4 9 0 0 9 9 8 6 ABC transporter PDR_CDR PF06422.12 CCU98787.1 - 5.1e-67 221.8 35.0 7.7e-23 80.2 0.0 8.7 9 0 0 9 9 7 3 CDR ABC transporter ABC_trans_N PF14510.6 CCU98787.1 - 1.8e-30 105.4 0.6 9.5e-11 42.2 0.1 3.8 3 0 0 3 3 3 3 ABC-transporter N-terminal RsgA_GTPase PF03193.16 CCU98787.1 - 1.1e-20 74.3 1.1 9e-06 25.7 0.0 4.2 4 0 0 4 4 4 3 RsgA GTPase AAA_16 PF13191.6 CCU98787.1 - 1.3e-17 64.7 10.4 0.0063 16.9 0.0 7.0 7 0 0 7 7 6 3 AAA ATPase domain ABC2_membrane_3 PF12698.7 CCU98787.1 - 1e-13 51.1 112.9 3.7e-06 26.3 12.5 7.5 6 2 0 6 6 6 6 ABC-2 family transporter protein AAA_22 PF13401.6 CCU98787.1 - 1.1e-13 51.6 0.8 0.2 12.0 0.0 6.6 6 0 0 6 6 6 3 AAA domain AAA_25 PF13481.6 CCU98787.1 - 1.5e-13 50.8 2.6 0.0042 16.7 0.0 5.8 6 0 0 6 6 6 3 AAA domain AAA_21 PF13304.6 CCU98787.1 - 3.4e-13 50.1 0.0 0.34 10.7 0.0 6.8 6 0 0 6 6 6 2 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 CCU98787.1 - 3e-11 43.5 2.8 0.74 9.7 0.0 6.3 6 0 0 6 6 6 3 NACHT domain AAA_18 PF13238.6 CCU98787.1 - 7.9e-10 39.4 0.9 1.4 9.5 0.0 6.3 6 0 0 6 6 6 2 AAA domain AAA_29 PF13555.6 CCU98787.1 - 1.6e-09 37.4 9.7 0.37 10.6 0.1 6.3 6 0 0 6 6 6 3 P-loop containing region of AAA domain cobW PF02492.19 CCU98787.1 - 2.9e-09 36.7 10.5 0.15 11.6 0.1 5.7 6 0 0 6 6 6 3 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 CCU98787.1 - 7.1e-09 35.8 0.0 0.24 11.3 0.0 3.6 3 0 0 3 3 3 3 Deoxynucleoside kinase SMC_N PF02463.19 CCU98787.1 - 1.9e-08 34.0 0.0 1.7 8.0 0.0 6.3 7 0 0 7 7 7 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CCU98787.1 - 9.6e-07 28.9 6.1 1.9 8.6 0.1 6.0 6 0 0 6 6 4 3 50S ribosome-binding GTPase AAA_23 PF13476.6 CCU98787.1 - 1.2e-06 29.2 2.7 1.8 9.0 0.1 3.8 3 0 0 3 3 3 3 AAA domain AAA_33 PF13671.6 CCU98787.1 - 1.4e-06 28.5 1.5 6.7 6.9 0.0 5.8 6 0 0 6 6 5 0 AAA domain AAA_28 PF13521.6 CCU98787.1 - 2.6e-06 27.8 3.7 8.2 6.6 0.0 5.7 6 0 0 6 6 6 0 AAA domain TsaE PF02367.17 CCU98787.1 - 5.3e-06 26.5 9.4 0.78 9.8 0.1 4.8 6 0 0 6 6 3 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CCU98787.1 - 7.6e-06 26.4 2.7 24 5.4 0.1 6.2 6 0 0 6 6 6 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CCU98787.1 - 8.3e-06 26.3 1.2 7.2 7.0 0.0 5.1 5 0 0 5 5 5 0 AAA domain AAA_24 PF13479.6 CCU98787.1 - 1.1e-05 25.2 2.4 6.4 6.5 0.0 5.0 6 0 0 6 6 4 0 AAA domain RNA_helicase PF00910.22 CCU98787.1 - 5e-05 23.7 0.2 18 5.7 0.0 4.9 5 0 0 5 5 3 0 RNA helicase AAA_30 PF13604.6 CCU98787.1 - 5.9e-05 22.9 11.3 3.7 7.2 0.1 6.0 6 0 0 6 6 6 1 AAA domain Zeta_toxin PF06414.12 CCU98787.1 - 6.5e-05 22.3 0.3 7.7 5.7 0.0 4.1 4 0 0 4 4 4 0 Zeta toxin Septin PF00735.18 CCU98787.1 - 7.6e-05 22.1 0.3 14 4.8 0.0 4.8 5 0 0 5 5 5 0 Septin Fcf2 PF08698.11 CCU98787.1 - 0.00034 21.0 0.5 0.19 12.1 0.1 2.8 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing PduV-EutP PF10662.9 CCU98787.1 - 0.00047 19.9 4.9 15 5.3 0.1 5.3 5 0 0 5 5 5 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 CCU98787.1 - 0.0017 18.6 1.4 35 4.6 0.0 4.3 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase DnaB_C PF03796.15 CCU98787.1 - 0.0032 16.8 1.0 21 4.3 0.0 4.7 6 0 0 6 6 5 0 DnaB-like helicase C terminal domain SKI PF01202.22 CCU98787.1 - 0.0047 17.1 0.1 29 4.7 0.0 3.5 3 0 0 3 3 3 0 Shikimate kinase SbcCD_C PF13558.6 CCU98787.1 - 0.0055 16.9 0.1 83 3.5 0.0 5.1 4 0 0 4 4 4 0 Putative exonuclease SbcCD, C subunit Rad51 PF08423.11 CCU98787.1 - 0.02 14.1 0.1 25 4.0 0.0 3.2 3 0 0 3 3 3 0 Rad51 ABC_ATPase PF09818.9 CCU98787.1 - 0.038 12.8 5.5 9.1 4.9 0.1 3.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 CCU98787.1 - 0.053 13.5 5.2 82 3.2 0.1 5.2 6 0 0 6 6 4 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CCU98787.1 - 0.064 12.8 1.9 64 3.0 0.0 3.9 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_15 PF13175.6 CCU98787.1 - 0.07 12.8 0.0 1.5e+02 1.8 0.0 4.8 6 0 0 6 6 5 0 AAA ATPase domain OAD_gamma PF04277.13 CCU98787.1 - 0.091 13.4 0.5 66 4.2 0.0 4.2 4 0 0 4 4 2 0 Oxaloacetate decarboxylase, gamma chain RuvB_N PF05496.12 CCU98787.1 - 0.13 12.0 5.4 40 3.9 0.1 4.0 4 0 0 4 4 3 0 Holliday junction DNA helicase RuvB P-loop domain Dynamin_N PF00350.23 CCU98787.1 - 0.2 11.7 0.1 1.2e+02 2.6 0.0 3.4 3 0 0 3 3 3 0 Dynamin family Pox_A32 PF04665.12 CCU98787.1 - 0.22 10.9 8.4 53 3.2 0.1 5.5 6 0 0 6 6 6 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 CCU98787.1 - 0.3 10.8 4.2 66 3.2 0.0 5.2 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein MobB PF03205.14 CCU98787.1 - 0.56 10.1 8.5 32 4.4 0.1 4.5 6 0 0 6 6 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 CCU98787.1 - 1.8 8.6 4.7 1.2e+02 2.6 0.1 3.7 3 0 0 3 3 3 0 Helicase HerA, central domain Glyco_transf_24 PF18404.1 CCU98788.1 - 7.9e-107 356.6 2.8 1.5e-106 355.8 2.8 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CCU98788.1 - 1e-36 127.2 1.5 1.2e-35 123.7 0.2 2.7 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CCU98788.1 - 2.2e-29 101.8 0.0 4.3e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 CCU98788.1 - 5.3e-27 94.9 2.3 1.2e-26 93.7 2.3 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CCU98788.1 - 3.7e-26 91.6 0.2 2.8e-25 88.8 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 CCU98788.1 - 4.3e-06 26.5 0.7 8.6e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 8 Innexin PF00876.18 CCU98788.1 - 0.02 14.2 0.2 0.035 13.4 0.2 1.3 1 0 0 1 1 1 0 Innexin HALZ PF02183.18 CCU98788.1 - 0.67 10.2 2.2 33 4.8 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper 5_nucleotid_C PF02872.18 CCU98789.1 - 6.3e-30 104.5 0.0 6e-29 101.3 0.0 2.0 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain HMG_box_2 PF09011.10 CCU98790.1 - 5.5e-13 49.3 13.5 1.3e-09 38.5 5.7 2.2 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 CCU98790.1 - 1.9e-12 47.4 19.6 2.7e-08 34.1 6.1 3.1 2 1 0 2 2 2 2 HMG (high mobility group) box Strep_SA_rep PF06696.11 CCU98790.1 - 0.0044 17.0 0.5 0.0044 17.0 0.5 2.4 2 0 0 2 2 2 1 Streptococcal surface antigen repeat DUF2115 PF09888.9 CCU98790.1 - 0.055 14.0 1.0 0.31 11.5 0.1 2.2 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) DUF1090 PF06476.12 CCU98790.1 - 0.5 10.5 10.8 0.1 12.7 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF2489 PF10675.9 CCU98790.1 - 2.6 8.0 7.5 0.47 10.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) PGI PF00342.19 CCU98791.1 - 1.5e-229 762.6 0.0 1.7e-229 762.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase KH_1 PF00013.29 CCU98792.1 - 0.0002 21.1 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 KH domain Totivirus_coat PF05518.11 CCU98792.1 - 5.7 4.9 6.0 6 4.8 6.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein DUF1744 PF08490.12 CCU98793.1 - 4e-123 410.9 0.0 1.2e-122 409.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CCU98793.1 - 1.2e-73 248.2 0.1 1.8e-73 247.6 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CCU98793.1 - 2.2e-10 39.9 0.0 6.1e-09 35.1 0.1 2.8 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CCU98793.1 - 8.5e-09 35.4 0.1 2.1e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CCU98793.1 - 0.00011 22.3 0.0 0.00038 20.5 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily UcrQ PF02939.16 CCU98795.1 - 1.6e-30 104.9 1.3 1.7e-30 104.8 1.3 1.0 1 0 0 1 1 1 1 UcrQ family Histone PF00125.24 CCU98797.1 - 5.8e-51 172.3 2.5 6.5e-51 172.1 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CCU98797.1 - 1.7e-05 25.1 0.0 2.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CCU98797.1 - 2.4e-05 24.4 0.5 3.7e-05 23.8 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CCU98797.1 - 0.00027 21.5 1.4 0.00032 21.3 1.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CCU98797.1 - 0.0073 16.6 0.1 0.014 15.7 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 CCU98797.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated WD40 PF00400.32 CCU98798.1 - 1.6e-21 76.2 14.9 0.00038 21.2 0.0 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU98798.1 - 2.8e-17 62.8 4.4 2.7e-08 34.0 0.3 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCU98798.1 - 4.1e-06 26.8 0.6 0.0016 18.4 0.1 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CCU98798.1 - 0.02 13.6 4.7 1 7.9 0.3 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 GMP_synt_C PF00958.22 CCU98799.1 - 3.7e-43 145.5 0.1 7.7e-43 144.5 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CCU98799.1 - 3.2e-38 131.4 0.0 7.2e-38 130.3 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CCU98799.1 - 1.2e-11 44.2 0.1 1.3e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CCU98799.1 - 3.5e-09 36.7 0.0 6.7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 CCU98799.1 - 0.00011 21.1 0.4 0.00024 20.0 0.2 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 CCU98799.1 - 0.00033 20.3 0.1 0.0009 18.9 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 CCU98799.1 - 0.0023 17.3 0.1 0.0043 16.4 0.1 1.4 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CCU98799.1 - 0.004 16.7 0.1 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 CCU98799.1 - 0.0079 15.9 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Asparagine synthase sCache_like PF16736.5 CCU98799.1 - 0.14 12.2 1.8 0.96 9.6 1.8 2.1 1 1 0 1 1 1 0 Single Cache-like WD40 PF00400.32 CCU98800.1 - 6.4e-13 49.0 2.2 8e-07 29.7 0.5 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Cys_Met_Meta_PP PF01053.20 CCU98801.1 - 8.5e-27 93.7 0.0 1.5e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SNARE PF05739.19 CCU98801.1 - 6e-15 55.0 1.5 7.9e-15 54.6 0.1 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 CCU98801.1 - 9.5e-06 24.7 0.0 2.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Aminotran_1_2 PF00155.21 CCU98801.1 - 2.4e-05 23.7 0.0 7.2e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Syntaxin PF00804.25 CCU98801.1 - 0.00022 20.9 13.1 0.00071 19.3 3.3 2.5 2 0 0 2 2 2 2 Syntaxin DUF1664 PF07889.12 CCU98801.1 - 2.7 8.1 6.2 1 9.4 0.5 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 CCU98801.1 - 2.8 8.2 5.6 4.5 7.5 0.9 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein DUF16 PF01519.16 CCU98801.1 - 3.8 8.1 4.7 1.9 9.0 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Muted PF14942.6 CCU98801.1 - 5.9 7.2 7.7 4 7.8 0.7 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Rnk_N PF14760.6 CCU98801.1 - 8.5 7.0 7.2 57 4.3 0.1 3.6 3 0 0 3 3 3 0 Rnk N-terminus Sdh_cyt PF01127.22 CCU98802.1 - 1.8e-23 82.9 1.9 2.4e-23 82.5 1.9 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Citrate_bind PF16114.5 CCU98803.1 - 2.5e-89 297.5 0.0 5.1e-89 296.5 0.0 1.6 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 CCU98803.1 - 1.2e-19 70.7 0.0 5.1e-17 62.0 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 CCU98803.1 - 1e-15 57.9 0.1 2.2e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 CCU98803.1 - 8.2e-11 42.5 0.0 1.7e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 CCU98803.1 - 6.6e-07 29.1 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 CCU98803.1 - 1.7e-06 27.9 0.0 4.3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GCP_N_terminal PF17681.1 CCU98804.1 - 7.3e-64 216.3 0.0 1.5e-63 215.3 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CCU98804.1 - 8.5e-42 143.7 12.7 8.5e-42 143.7 12.7 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Rsd_AlgQ PF04353.13 CCU98804.1 - 0.02 14.8 0.2 0.056 13.4 0.2 1.7 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TP_methylase PF00590.20 CCU98805.1 - 3e-40 138.5 1.8 5.3e-40 137.6 1.8 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 CCU98805.1 - 6.9e-11 42.5 0.0 1.5e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 CCU98805.1 - 2.1e-10 39.8 0.1 4.2e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 CCU98805.1 - 1.1e-08 34.5 0.1 1.1e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal SAM_decarbox PF01536.16 CCU98806.1 - 1.2e-130 435.7 0.0 1.5e-130 435.3 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Peptidase_M16_C PF05193.21 CCU98807.1 - 1.7e-18 67.3 0.0 1.8e-14 54.2 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCU98807.1 - 2.5e-07 30.8 0.0 5.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Erythro-docking PF09277.11 CCU98807.1 - 0.047 13.6 0.8 0.19 11.7 0.8 2.0 1 0 0 1 1 1 0 Erythronolide synthase, docking M16C_assoc PF08367.11 CCU98807.1 - 0.57 9.3 1.3 7.9 5.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase M16C associated Xan_ur_permease PF00860.20 CCU98808.1 - 3.5e-21 75.4 21.0 1.8e-13 50.0 7.8 2.1 2 0 0 2 2 2 2 Permease family Sulfate_transp PF00916.20 CCU98808.1 - 0.00021 20.1 4.9 0.00021 20.1 4.9 2.3 2 2 1 3 3 3 1 Sulfate permease family Polysacc_deac_1 PF01522.21 CCU98809.1 - 3.9e-29 101.1 0.0 7.4e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Cu_amine_oxidN1 PF07833.11 CCU98809.1 - 0.034 14.6 0.1 0.077 13.5 0.1 1.6 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain Catalase PF00199.19 CCU98810.1 - 1.2e-174 580.9 0.0 1.5e-174 580.6 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CCU98810.1 - 1.5e-19 69.9 0.0 3.2e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 CCU98810.1 - 3.1e-11 43.1 0.2 5.5e-11 42.3 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 CCU98810.1 - 0.0016 18.3 0.1 0.0026 17.6 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Polysacc_deac_1 PF01522.21 CCU98811.1 - 1.1e-16 60.9 0.0 3.2e-10 40.0 0.0 2.5 1 1 1 2 2 2 2 Polysaccharide deacetylase SPX PF03105.19 CCU98811.1 - 0.047 13.6 5.2 0.07 13.0 5.2 1.2 1 0 0 1 1 1 0 SPX domain FAM70 PF14967.6 CCU98811.1 - 0.079 12.4 3.7 0.16 11.4 3.7 1.5 1 0 0 1 1 1 0 FAM70 protein RhoGAP PF00620.27 CCU98813.1 - 2.9e-33 114.8 0.0 8e-33 113.4 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 CCU98813.1 - 4.7e-28 97.2 37.7 3.4e-12 46.4 3.5 4.8 5 0 0 5 5 5 4 LIM domain Aa_trans PF01490.18 CCU98814.1 - 3.9e-35 121.3 8.0 4.8e-35 121.1 8.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CCU98814.1 - 1.3e-05 24.4 7.5 1.8e-05 24.0 7.5 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 CCU98815.1 - 1.7e-26 92.9 1.9 5.4e-26 91.2 0.4 1.9 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein SPT_ssu-like PF11779.8 CCU98815.1 - 3.9 7.2 7.9 11 5.7 0.8 2.5 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like Rad21_Rec8_N PF04825.13 CCU98816.1 - 1.4e-19 70.3 0.0 2.9e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CCU98816.1 - 3.8e-12 45.3 0.0 6.5e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 CCU98816.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Sterol-sensing PF12349.8 CCU98817.1 - 2.1e-33 115.3 11.4 2.1e-33 115.3 11.4 2.1 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CCU98817.1 - 8.9e-08 30.7 9.2 1.3e-07 30.2 9.2 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 CCU98817.1 - 0.031 15.1 0.2 1.2 10.1 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat TPR_1 PF00515.28 CCU98818.1 - 1.1e-26 91.5 3.5 3e-08 33.1 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCU98818.1 - 2.5e-22 77.1 3.7 3e-07 30.0 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCU98818.1 - 6.6e-19 67.3 6.5 4.2e-08 32.7 0.7 3.3 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 CCU98818.1 - 6.2e-17 60.3 2.3 1.6e-05 24.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCU98818.1 - 6.2e-13 48.2 0.2 1.1e-05 25.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCU98818.1 - 5.7e-12 45.4 2.3 0.00022 21.8 0.0 4.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CCU98818.1 - 1.4e-11 44.8 4.9 9.6e-07 29.4 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCU98818.1 - 7.6e-11 42.4 1.0 1.9e-06 28.3 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCU98818.1 - 7.1e-09 35.1 0.3 0.0004 20.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CCU98818.1 - 1.5e-08 34.2 3.3 0.0062 16.4 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCU98818.1 - 1.6e-08 34.7 6.1 4e-06 27.0 1.5 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 CCU98818.1 - 1.1e-06 29.1 0.3 0.00015 22.2 0.1 2.3 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 CCU98818.1 - 1.2e-05 25.4 0.1 0.0033 17.5 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CCU98818.1 - 3.9e-05 23.0 0.7 0.00015 21.0 0.1 2.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 CCU98818.1 - 0.00035 20.9 0.1 0.074 13.7 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CCU98818.1 - 0.0021 18.6 4.3 4.6 8.1 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 CCU98818.1 - 0.21 11.5 0.5 0.52 10.2 0.1 1.9 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal STI1 PF17830.1 CCU98818.1 - 1 9.3 13.0 26 4.8 0.2 3.0 1 1 0 2 2 2 0 STI1 domain XPC-binding PF09280.11 CCU98818.1 - 2 8.2 12.8 12 5.7 0.6 3.4 3 0 0 3 3 3 0 XPC-binding domain MIT PF04212.18 CCU98818.1 - 2 8.5 10.9 3.6 7.7 2.3 3.7 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain 6PGD PF00393.19 CCU98819.1 - 6.9e-125 416.2 0.0 8.3e-125 415.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CCU98819.1 - 3.3e-35 121.6 0.0 5.3e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CCU98819.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DEAD PF00270.29 CCU98820.1 - 1.5e-20 73.7 0.0 2.8e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU98820.1 - 3.7e-19 69.1 0.0 4e-17 62.6 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain RQC PF09382.10 CCU98820.1 - 5.1e-18 64.9 0.0 8.6e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 CCU98820.1 - 3.5e-16 59.7 3.1 1.3e-15 57.9 2.7 2.3 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 CCU98820.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ras PF00071.22 CCU98821.1 - 4.3e-50 169.5 0.0 5.1e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCU98821.1 - 6.6e-19 68.3 0.0 1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU98821.1 - 1.1e-08 34.8 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 CCU98821.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 CCU98821.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 CCU98821.1 - 0.16 12.5 0.0 0.27 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CCU98821.1 - 0.2 11.5 0.0 20 5.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MFS_1_like PF12832.7 CCU98822.1 - 0.00038 19.4 0.0 0.0013 17.7 0.0 1.8 2 1 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 CCU98822.1 - 0.0052 15.4 18.5 0.0051 15.4 12.9 3.0 2 1 0 2 2 2 1 MFS/sugar transport protein GTP_EFTU PF00009.27 CCU98823.1 - 4.4e-41 140.6 0.0 6.6e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 CCU98823.1 - 1.2e-33 116.2 5.4 1.9e-33 115.7 5.4 1.3 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 CCU98823.1 - 9e-23 80.4 0.0 2.8e-22 78.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CCU98823.1 - 1.6e-19 69.7 0.0 4.7e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCU98823.1 - 4.6e-06 26.9 0.0 8.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCU98823.1 - 3.2e-05 24.0 0.0 6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 CCU98823.1 - 8.2e-05 22.6 0.0 0.0003 20.8 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II Roc PF08477.13 CCU98823.1 - 0.026 14.7 0.0 0.16 12.2 0.0 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CCU98823.1 - 0.16 11.6 0.0 0.48 10.0 0.0 1.7 1 1 0 1 1 1 0 Ras family SRPRB PF09439.10 CCU98823.1 - 0.18 11.2 0.0 0.46 9.9 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.29 CCU98824.1 - 2e-12 47.7 0.0 3.4e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCU98824.1 - 2.9e-05 24.5 0.2 0.017 15.5 0.1 3.0 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 CCU98824.1 - 0.00015 21.5 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CCU98824.1 - 0.00037 20.5 0.0 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_2 PF07724.14 CCU98824.1 - 0.00047 20.3 0.0 0.00075 19.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCU98824.1 - 0.00083 19.4 0.0 0.0022 18.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CCU98824.1 - 0.0012 18.9 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCU98824.1 - 0.0012 19.1 0.0 0.0054 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CCU98824.1 - 0.002 17.7 0.5 0.28 10.7 0.2 2.7 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CCU98824.1 - 0.0028 17.8 0.2 0.0071 16.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_assoc_2 PF16193.5 CCU98824.1 - 0.0081 16.5 0.1 0.02 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_28 PF13521.6 CCU98824.1 - 0.015 15.6 0.3 0.096 12.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CCU98824.1 - 0.035 14.6 0.0 0.085 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CCU98824.1 - 0.036 14.0 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 CCU98824.1 - 0.045 13.0 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 CCU98824.1 - 0.059 13.1 1.1 0.098 12.4 0.3 1.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CCU98824.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 CCU98824.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CCU98824.1 - 0.18 11.7 0.1 0.54 10.2 0.0 1.7 1 1 1 2 2 2 0 NTPase ATPase PF06745.13 CCU98824.1 - 0.22 10.8 0.0 0.57 9.5 0.0 1.5 2 0 0 2 2 2 0 KaiC Viral_helicase1 PF01443.18 CCU98824.1 - 0.23 11.2 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Exo_endo_phos PF03372.23 CCU98825.1 - 3.7e-13 49.6 0.2 4.8e-13 49.2 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Brr6_like_C_C PF10104.9 CCU98825.1 - 0.24 11.2 0.0 0.37 10.6 0.0 1.2 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Pyridoxal_deC PF00282.19 CCU98826.1 - 3.5e-63 213.6 0.0 4.8e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CCU98826.1 - 0.00032 19.8 0.0 0.00049 19.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Lactamase_B_2 PF12706.7 CCU98826.1 - 0.012 15.1 1.3 0.036 13.6 1.3 1.8 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ribosomal_L10 PF00466.20 CCU98827.1 - 6.8e-25 87.1 0.5 2.8e-24 85.1 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 CCU98827.1 - 1.2e-22 80.2 8.2 1.2e-22 80.2 8.2 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 CCU98827.1 - 4.9e-21 74.5 0.0 8.1e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P ECH_1 PF00378.20 CCU98829.1 - 7.4e-40 136.8 1.0 1e-19 70.9 0.3 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CCU98829.1 - 1.3e-07 31.4 0.1 0.0052 16.3 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase B12-binding_2 PF02607.17 CCU98829.1 - 0.1 13.0 3.2 17 5.9 0.0 3.2 3 1 0 3 3 3 0 B12 binding domain WD40 PF00400.32 CCU98830.1 - 1.1e-14 54.5 0.6 0.0011 19.7 0.0 5.2 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU98830.1 - 3.4e-09 36.9 0.0 0.012 15.9 0.0 4.7 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CCU98830.1 - 0.0084 15.7 0.2 2 7.9 0.1 2.7 1 1 1 2 2 2 2 PQQ-like domain DUF5018 PF16410.5 CCU98830.1 - 0.15 10.7 0.0 0.31 9.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) Frtz PF11768.8 CCU98830.1 - 0.22 9.8 0.0 4.6 5.4 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz SAS4 PF15460.6 CCU98831.1 - 8.4e-05 22.6 2.2 0.00014 21.9 2.2 1.4 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.6 CCU98831.1 - 0.0016 19.1 0.7 0.0016 19.1 0.7 2.0 2 0 0 2 2 2 1 PEHE domain Spc7 PF08317.11 CCU98831.1 - 0.9 8.4 5.5 1.4 7.7 1.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein CHORD PF04968.12 CCU98832.1 - 2.6e-40 136.9 7.9 1.2e-21 77.2 2.6 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 CCU98832.1 - 1.5e-06 29.1 0.0 2.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 CS domain BTK PF00779.19 CCU98832.1 - 0.046 13.5 10.8 0.14 12.0 3.8 3.3 3 1 0 3 3 3 0 BTK motif ADH_zinc_N PF00107.26 CCU98835.1 - 2.2e-10 40.6 0.0 3.7e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCU98835.1 - 0.01 16.9 0.0 0.042 14.9 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.12 CCU98835.1 - 0.012 15.4 0.2 0.046 13.6 0.1 2.1 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain AA_permease PF00324.21 CCU98836.1 - 5.9e-125 417.6 32.3 7.3e-125 417.3 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCU98836.1 - 1.3e-29 103.3 35.0 1.8e-29 102.9 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease Syja_N PF02383.18 CCU98837.1 - 2.1e-69 234.3 0.0 3.6e-69 233.5 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Pyr_redox_2 PF07992.14 CCU98837.1 - 2.9e-39 135.1 0.0 4.5e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCU98837.1 - 1.2e-10 41.8 0.1 4.8e-08 33.5 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Exo_endo_phos PF03372.23 CCU98837.1 - 1.3e-10 41.2 0.0 2.9e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family EF-hand_1 PF00036.32 CCU98837.1 - 2e-06 27.0 1.0 0.0035 16.8 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CCU98837.1 - 9.1e-06 25.2 0.7 0.022 14.7 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CCU98837.1 - 3.2e-05 24.3 0.2 0.19 12.2 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CCU98837.1 - 0.018 14.5 0.8 0.051 13.1 0.3 2.1 2 0 0 2 2 2 0 EF hand Baculo_PEP_C PF04513.12 CCU98838.1 - 0.008 16.2 0.8 0.008 16.2 0.8 4.6 4 1 1 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_M16_C PF05193.21 CCU98839.1 - 8.2e-41 140.0 0.0 2.3e-40 138.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCU98839.1 - 1.2e-38 132.4 0.0 2e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) OTCace_N PF02729.21 CCU98839.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Hydrolase_4 PF12146.8 CCU98840.1 - 3.7e-26 91.9 0.2 6.5e-26 91.1 0.2 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCU98840.1 - 7.9e-10 39.7 0.4 1.1e-09 39.2 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CCU98840.1 - 7.8e-05 22.4 0.5 0.0061 16.2 0.1 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 CCU98840.1 - 0.0014 18.2 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CCU98840.1 - 0.0031 17.0 0.1 0.027 13.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CCU98840.1 - 0.0098 15.5 0.2 2.1 7.9 0.1 2.4 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Linker_histone PF00538.19 CCU98841.1 - 8.1e-06 26.1 0.0 1.8e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Pkinase PF00069.25 CCU98842.1 - 3.8e-09 36.3 0.0 5.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CCU98842.1 - 5.4e-07 29.8 1.0 9.2e-07 29.0 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCU98842.1 - 7.1e-05 21.7 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CCU98842.1 - 0.00042 19.7 0.1 0.0013 18.1 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCU98842.1 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 CCU98842.1 - 0.019 14.6 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase IPK PF03770.16 CCU98843.1 - 3e-52 177.4 0.0 5.2e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_L14e PF01929.17 CCU98844.1 - 4.1e-32 110.5 3.4 5.9e-32 110.0 3.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CCU98844.1 - 0.048 13.6 0.5 0.048 13.6 0.5 1.8 2 0 0 2 2 2 0 KOW motif Oxidored_q6 PF01058.22 CCU98844.1 - 0.053 13.4 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Ribosomal_S8 PF00410.19 CCU98845.1 - 7.5e-21 74.4 0.1 2e-20 73.0 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.18 CCU98846.1 - 7.8e-59 196.9 0.0 9.9e-59 196.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Glyco_hydro_8 PF01270.17 CCU98847.1 - 4.9e-15 55.2 0.1 6.2e-14 51.6 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 8 DNA_pol_A_exo1 PF01612.20 CCU98848.1 - 7.8e-19 68.0 0.0 1.2e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease RAC_head PF16717.5 CCU98849.1 - 9.5e-18 65.0 1.1 9.5e-18 65.0 1.1 3.1 4 0 0 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 CCU98849.1 - 6.1e-16 58.3 0.1 1.9e-15 56.7 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain DUF5427 PF10310.9 CCU98849.1 - 0.61 9.0 15.8 0.93 8.4 15.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Presenilin PF01080.17 CCU98849.1 - 5.4 5.7 8.8 7.8 5.1 8.8 1.3 1 0 0 1 1 1 0 Presenilin tRNA-synt_2b PF00587.25 CCU98850.1 - 5.7e-36 124.2 0.0 9.6e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CCU98850.1 - 4.7e-23 81.5 5.9 9.1e-23 80.6 5.9 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 CCU98850.1 - 0.03 14.4 0.9 0.075 13.1 0.9 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1298 PF06974.13 CCU98850.1 - 0.047 13.6 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) ProRS-C_1 PF09180.11 CCU98851.1 - 3e-28 97.8 0.1 5.7e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 CCU98851.1 - 1e-18 67.9 0.0 2e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CCU98851.1 - 4.5e-17 62.0 0.1 7.4e-16 58.1 0.0 3.1 5 0 0 5 5 5 1 Anticodon binding domain tRNA_edit PF04073.15 CCU98851.1 - 1.4e-13 51.0 0.4 2.4e-13 50.2 0.4 1.3 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain SRP19 PF01922.17 CCU98852.1 - 4.6e-07 30.7 0.1 2.6e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 SRP19 protein DUF3617 PF12276.8 CCU98852.1 - 0.42 10.9 3.4 0.9 9.9 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) GET2 PF08690.10 CCU98852.1 - 1.4 8.5 3.9 0.57 9.8 0.8 1.7 2 0 0 2 2 2 0 GET complex subunit GET2 SKN1 PF03935.15 CCU98853.1 - 1.5e-180 600.9 0.6 1.9e-180 600.5 0.6 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DEAD PF00270.29 CCU98854.1 - 2.7e-21 76.1 0.0 5.1e-21 75.2 0.0 1.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU98854.1 - 0.0047 17.3 0.1 0.009 16.3 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fer2 PF00111.27 CCU98855.1 - 6.4e-12 45.3 0.2 8.9e-12 44.8 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Sugar_tr PF00083.24 CCU98856.1 - 1.9e-58 198.4 14.7 2.7e-58 197.9 14.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCU98856.1 - 3.5e-07 29.5 45.3 3.9e-07 29.3 42.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 CCU98857.1 - 6.6e-17 61.6 8.8 3.5e-05 24.5 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU98857.1 - 2.2e-15 56.7 2.8 0.00019 21.7 0.0 4.9 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCU98857.1 - 0.00018 20.6 0.4 0.0054 15.7 0.0 2.7 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CCU98857.1 - 0.00046 20.1 0.0 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IN_DBD_C PF00552.21 CCU98857.1 - 0.0017 17.6 0.0 0.0049 16.1 0.0 1.8 1 0 0 1 1 1 1 Integrase DNA binding domain IKI3 PF04762.12 CCU98857.1 - 0.0034 15.5 0.4 0.087 10.8 0.2 2.4 2 1 1 3 3 3 1 IKI3 family Pkinase PF00069.25 CCU98858.1 - 7.7e-74 248.4 0.0 8.9e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98858.1 - 4.5e-35 121.2 0.0 5.9e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCU98858.1 - 0.00063 18.8 0.0 0.0097 14.9 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CCU98858.1 - 0.031 14.2 0.0 0.12 12.2 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CCU98858.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 CCU98858.1 - 0.078 12.0 0.0 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Utp12 PF04003.12 CCU98859.1 - 1.1e-22 80.3 0.5 2.1e-22 79.5 0.5 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 CCU98859.1 - 0.00063 20.5 0.1 0.0085 16.9 0.1 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat BUD22 PF09073.10 CCU98859.1 - 1.7 7.9 28.6 2.7 7.2 28.6 1.3 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 CCU98859.1 - 8.2 5.9 26.1 16 5.0 26.1 1.4 1 0 0 1 1 1 0 PPP4R2 Cut8 PF08559.10 CCU98861.1 - 1.8e-12 47.4 0.0 4.5e-12 46.1 0.0 1.5 2 0 0 2 2 2 1 Cut8, nuclear proteasome tether protein TraD PF06412.11 CCU98861.1 - 0.0093 15.7 0.2 0.026 14.3 0.2 1.7 1 0 0 1 1 1 1 Conjugal transfer protein TraD PRELI PF04707.14 CCU98862.1 - 9.6e-19 67.7 0.0 1.3e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family DUF866 PF05907.13 CCU98862.1 - 0.17 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Suf PF05843.14 CCU98863.1 - 1.3e-72 245.3 4.3 7.9e-69 232.9 0.0 3.3 3 0 0 3 3 3 3 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 CCU98863.1 - 0.0058 15.8 8.7 0.041 13.0 0.0 4.4 3 2 1 4 4 4 1 NRDE-2, necessary for RNA interference MEIOC PF15189.6 CCU98863.1 - 0.27 10.8 2.9 0.67 9.6 2.9 1.6 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC TPR_1 PF00515.28 CCU98864.1 - 1.7e-43 144.7 20.1 2.8e-06 26.9 0.1 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 CCU98864.1 - 5.3e-36 119.8 21.1 0.00012 22.0 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat STI1 PF17830.1 CCU98864.1 - 2.2e-32 110.7 19.2 5.4e-18 64.7 4.7 4.1 5 1 1 6 6 4 2 STI1 domain TPR_8 PF13181.6 CCU98864.1 - 2.9e-21 73.8 15.4 0.0016 18.5 0.0 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 CCU98864.1 - 1.8e-20 73.0 22.8 3.5e-10 40.0 0.0 6.5 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CCU98864.1 - 3.1e-18 65.2 19.5 1e-06 28.3 0.0 7.4 6 1 1 7 7 7 5 TPR repeat TPR_14 PF13428.6 CCU98864.1 - 1.3e-17 63.0 11.4 0.0082 16.9 0.9 8.9 4 3 4 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 CCU98864.1 - 8.3e-16 58.4 23.6 0.00031 21.3 1.9 7.3 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 CCU98864.1 - 5.1e-15 55.7 22.2 0.0016 18.9 0.2 7.2 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCU98864.1 - 2.2e-11 43.3 1.3 0.15 12.5 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCU98864.1 - 4.6e-11 41.9 7.7 0.029 14.4 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 CCU98864.1 - 2.2e-10 40.0 16.0 0.0013 18.5 0.0 8.7 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 CCU98864.1 - 3.8e-06 27.0 7.8 0.13 12.5 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 CCU98864.1 - 0.00098 19.6 14.7 16 6.4 0.0 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat NARP1 PF12569.8 CCU98864.1 - 0.0022 17.0 1.1 0.0022 17.0 1.1 2.7 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 CCU98864.1 - 0.011 16.0 11.1 0.68 10.2 0.7 4.3 4 2 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 CCU98864.1 - 0.063 12.6 0.1 0.063 12.6 0.1 3.8 4 0 0 4 4 4 0 MalT-like TPR region SprT-like PF10263.9 CCU98864.1 - 0.12 12.3 0.0 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 SprT-like family GerD PF17898.1 CCU98864.1 - 0.15 12.0 3.8 0.96 9.4 0.9 3.0 2 1 0 2 2 2 0 Spore germination GerD central core domain XPC-binding PF09280.11 CCU98864.1 - 0.17 11.7 3.3 1.1 9.0 1.4 2.8 2 0 0 2 2 2 0 XPC-binding domain TPR_4 PF07721.14 CCU98864.1 - 0.36 11.6 3.0 20 6.2 0.0 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat RNA_pol_3_Rpc31 PF11705.8 CCU98865.1 - 6.7e-22 78.8 1.2 1e-21 78.3 1.2 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PsiB PF06290.11 CCU98865.1 - 0.075 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) Zn_clus PF00172.18 CCU98866.1 - 1.5e-06 28.2 5.4 2.5e-06 27.5 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup192 PF11894.8 CCU98867.1 - 1.3e-200 669.0 0.0 1.6e-200 668.7 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Urb2 PF10441.9 CCU98867.1 - 0.0055 16.7 3.7 0.083 12.8 0.2 2.9 2 0 0 2 2 2 2 Urb2/Npa2 family CDT1_C PF16679.5 CCU98867.1 - 1.6 9.2 5.2 1.3 9.5 0.6 2.8 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Pyridoxal_deC PF00282.19 CCU98868.1 - 4.9e-102 341.5 0.0 6.3e-102 341.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain EI24 PF07264.11 CCU98870.1 - 1.8e-08 34.8 4.1 4.1e-08 33.7 4.1 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) TruB_N PF01509.18 CCU98873.1 - 9.4e-38 129.9 0.0 6.6e-37 127.2 0.0 1.9 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CCU98873.1 - 1.2e-07 31.8 1.3 3.5e-07 30.3 0.2 2.4 3 0 0 3 3 3 1 tRNA pseudouridylate synthase B C-terminal domain Formyl_trans_N PF00551.19 CCU98874.1 - 6.5e-20 71.6 0.0 8.2e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Ysc84 PF04366.12 CCU98875.1 - 6.7e-40 135.8 0.0 1.8e-39 134.4 0.0 1.6 2 0 0 2 2 2 1 Las17-binding protein actin regulator Esterase PF00756.20 CCU98876.1 - 1.4e-45 155.9 0.0 1.6e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 CCU98876.1 - 1.3e-06 28.0 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CCU98876.1 - 0.00033 20.0 0.0 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 CCU98876.1 - 0.00087 18.8 0.0 0.03 13.8 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 CCU98876.1 - 0.023 15.3 0.9 0.053 14.1 0.7 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CCU98876.1 - 0.044 13.4 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DnaJ PF00226.31 CCU98877.1 - 3e-10 40.1 0.1 5.1e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain CPBP PF02517.16 CCU98879.1 - 0.00023 21.5 3.0 0.00023 21.5 3.0 2.1 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Inositol_P PF00459.25 CCU98880.1 - 7.6e-51 173.2 0.1 3.5e-50 171.0 0.1 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family DUF5559 PF17714.1 CCU98880.1 - 0.024 14.5 0.2 0.037 13.9 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5559) AAA_5 PF07728.14 CCU98882.1 - 1.6e-68 229.0 0.0 2.3e-28 98.9 0.0 3.4 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CCU98882.1 - 0.0022 17.9 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCU98882.1 - 0.0031 17.9 0.9 5.7 7.3 0.0 4.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_2 PF07724.14 CCU98882.1 - 0.046 13.8 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA PF00004.29 CCU98882.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 CCU98882.1 - 0.14 12.4 0.1 0.63 10.3 0.1 2.1 2 0 0 2 2 2 0 Midasin AAA lid domain Raptor_N PF14538.6 CCU98883.1 - 2e-61 206.3 0.0 3.1e-61 205.6 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 CCU98883.1 - 2.9e-05 24.7 3.1 0.64 11.0 0.1 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.22 CCU98883.1 - 0.00013 21.9 15.9 0.0049 17.0 0.1 6.5 7 0 0 7 7 7 1 HEAT repeat ANAPC4_WD40 PF12894.7 CCU98883.1 - 0.0028 17.9 0.0 53 4.2 0.0 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 CCU98883.1 - 0.04 14.0 0.1 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCU98883.1 - 0.34 11.3 6.5 0.24 11.8 0.4 3.7 3 1 1 4 4 4 0 HEAT repeats IBN_N PF03810.19 CCU98884.1 - 2.9e-08 33.5 0.0 9.7e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain TAF6_C PF07571.13 CCU98884.1 - 0.00043 20.5 0.0 0.065 13.6 0.0 3.6 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain HEAT_2 PF13646.6 CCU98884.1 - 0.029 14.7 0.7 0.029 14.7 0.7 6.0 5 1 1 6 6 6 0 HEAT repeats Cse1 PF08506.10 CCU98884.1 - 0.071 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Cse1 CP_ATPgrasp_1 PF04174.13 CCU98884.1 - 0.13 11.3 0.7 1.4 7.9 0.2 2.2 2 0 0 2 2 2 0 A circularly permuted ATPgrasp HEAT PF02985.22 CCU98884.1 - 1.4 9.4 6.4 7.6 7.1 0.1 5.0 4 0 0 4 4 4 0 HEAT repeat Torus PF16131.5 CCU98885.1 - 1.4e-07 32.1 0.1 1.2e-05 26.0 0.1 2.4 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 CCU98885.1 - 1.6e-05 25.2 7.9 1.6e-05 25.2 7.9 2.4 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Ank_2 PF12796.7 CCU98885.1 - 6.5e-05 23.4 0.0 0.00014 22.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-CCCH PF00642.24 CCU98885.1 - 0.00024 20.9 12.7 0.018 15.0 3.8 2.7 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_4 PF13637.6 CCU98885.1 - 0.00047 20.7 0.1 0.00098 19.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-CCCH_4 PF18044.1 CCU98885.1 - 0.00061 19.5 15.0 0.0014 18.3 5.9 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Ank_3 PF13606.6 CCU98885.1 - 0.00095 19.5 0.2 0.17 12.6 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CCU98885.1 - 0.0056 17.0 0.3 0.6 10.5 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) zf_CCCH_4 PF18345.1 CCU98885.1 - 0.05 13.7 1.8 0.05 13.7 1.8 2.8 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 CCU98885.1 - 0.53 10.5 3.7 20 5.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger containing family Pkinase PF00069.25 CCU98886.1 - 7.4e-56 189.4 0.0 9.7e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98886.1 - 4.2e-23 81.9 0.1 7.1e-23 81.2 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase BolA PF01722.18 CCU98886.1 - 7.7e-08 32.5 0.2 3.2e-07 30.5 0.1 2.0 1 1 1 2 2 2 1 BolA-like protein RIO1 PF01163.22 CCU98886.1 - 2.2e-05 24.1 0.1 0.00051 19.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 CCU98886.1 - 0.00059 19.3 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CCU98886.1 - 0.017 14.1 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CCU98886.1 - 0.025 13.9 0.1 0.058 12.7 0.0 1.6 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CCU98886.1 - 0.04 13.8 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family 3Beta_HSD PF01073.19 CCU98887.1 - 1.2e-58 198.4 0.0 1.4e-54 185.0 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CCU98887.1 - 8.2e-26 90.9 0.0 1.6e-25 90.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CCU98887.1 - 1.3e-12 47.8 0.0 3e-10 40.0 0.0 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CCU98887.1 - 6.7e-12 45.1 0.0 3.7e-09 36.1 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 CCU98887.1 - 5.3e-10 38.9 0.0 8e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CCU98887.1 - 4.4e-09 36.5 0.0 7.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CCU98887.1 - 0.0026 16.9 0.0 0.009 15.2 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CCU98887.1 - 0.14 11.7 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family KR PF08659.10 CCU98887.1 - 0.14 12.1 0.1 0.64 9.9 0.1 2.0 1 1 0 1 1 1 0 KR domain ACBP PF00887.19 CCU98889.1 - 3.3e-29 100.9 0.1 6.1e-29 100.1 0.0 1.4 1 1 1 2 2 2 1 Acyl CoA binding protein 7TM_GPCR_Sru PF10322.9 CCU98890.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru Methyltransf_12 PF08242.12 CCU98892.1 - 9.1e-14 52.0 0.0 6.9e-13 49.2 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCU98892.1 - 2e-13 50.5 0.0 6.2e-13 48.9 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCU98892.1 - 5.1e-12 46.4 0.0 4.7e-11 43.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCU98892.1 - 5.1e-09 36.7 0.0 2.9e-08 34.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CCU98892.1 - 1.3e-06 27.8 0.0 0.0025 17.1 0.0 2.2 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.6 CCU98892.1 - 4.5e-06 26.5 0.0 3.6e-05 23.6 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 CCU98892.1 - 0.013 16.5 0.0 0.051 14.6 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain CheR PF01739.18 CCU98892.1 - 0.041 13.4 0.0 10 5.6 0.0 2.4 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_8 PF05148.15 CCU98892.1 - 0.054 13.3 0.0 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase MTS PF05175.14 CCU98892.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Sas10 PF09368.10 CCU98892.1 - 0.12 12.9 0.3 0.22 12.0 0.3 1.5 1 0 0 1 1 1 0 Sas10 C-terminal domain Ham1p_like PF01725.16 CCU98893.1 - 0.00028 20.9 0.0 0.00028 20.9 0.0 1.1 1 0 0 1 1 1 1 Ham1 family Ham1p_like PF01725.16 CCU98894.1 - 3.3e-26 92.4 0.0 4.4e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Ham1 family GTP_EFTU PF00009.27 CCU98898.1 - 1.1e-66 224.1 0.1 1.6e-66 223.6 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CCU98898.1 - 4.5e-33 113.6 0.0 1.1e-32 112.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CCU98898.1 - 1.4e-20 73.1 0.0 3e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCU98898.1 - 1.1e-12 48.1 0.0 4e-12 46.3 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CCU98898.1 - 1.9e-12 47.1 0.0 4.9e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CCU98898.1 - 0.001 19.2 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase NARP1 PF12569.8 CCU98899.1 - 1.4e-136 456.5 13.0 4.1e-121 405.4 12.1 2.6 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CCU98899.1 - 4.6e-12 45.1 27.6 2.5e-05 24.0 0.1 8.4 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CCU98899.1 - 1.1e-10 41.4 36.0 0.6 11.1 0.0 12.0 8 3 3 12 12 12 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCU98899.1 - 1.9e-08 33.8 7.3 0.0016 18.2 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CCU98899.1 - 3.3e-05 24.0 0.4 3.3e-05 24.0 0.4 7.2 9 2 0 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCU98899.1 - 8.9e-05 22.6 12.3 0.012 15.9 0.6 5.2 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CCU98899.1 - 0.00013 21.7 13.7 0.026 14.6 0.1 6.4 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCU98899.1 - 0.00017 22.0 1.0 0.00017 22.0 1.0 8.0 7 2 1 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCU98899.1 - 0.0083 15.8 0.5 3.3 7.5 0.0 3.7 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 CCU98899.1 - 0.012 15.8 3.5 1.7 9.1 0.1 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCU98899.1 - 0.02 15.2 0.0 0.02 15.2 0.0 7.6 8 1 1 9 9 7 0 Tetratricopeptide repeat Transcrip_act PF04949.13 CCU98899.1 - 0.033 14.1 0.2 0.1 12.5 0.2 1.9 1 0 0 1 1 1 0 Transcriptional activator Fis1_TPR_C PF14853.6 CCU98899.1 - 0.11 12.6 7.9 13 6.0 0.0 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 CCU98899.1 - 0.24 12.1 0.0 0.24 12.1 0.0 7.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 CCU98899.1 - 0.34 10.9 0.1 0.34 10.9 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CCU98899.1 - 0.59 9.8 6.9 15 5.3 0.2 3.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 CCU98899.1 - 6.3 7.5 43.5 0.075 13.7 1.8 9.1 10 0 0 10 10 8 0 Tetratricopeptide repeat C2 PF00168.30 CCU98900.1 - 9.7e-08 32.2 0.0 1.6e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 CCU98900.1 - 7.1e-06 26.6 1.0 1.4e-05 25.7 0.1 2.1 2 1 0 2 2 2 1 Protein kinase C terminal domain 2OG-FeII_Oxy_4 PF13661.6 CCU98900.1 - 0.13 13.0 0.0 0.22 12.2 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PP-binding PF00550.25 CCU98901.1 - 3.7e-15 56.0 0.2 5.2e-15 55.5 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CCU98901.1 - 8.7e-06 25.9 0.1 1.2e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.9 CCU98901.1 - 0.16 12.1 0.0 0.23 11.6 0.0 1.3 1 1 0 1 1 1 0 Ribosomal subunit 39S Ribosomal_L17 PF01196.19 CCU98902.1 - 7.9e-30 103.6 0.9 2.5e-29 102.0 0.0 2.2 3 0 0 3 3 3 1 Ribosomal protein L17 DUF1382 PF07131.11 CCU98902.1 - 0.0086 16.1 0.1 0.055 13.5 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1382) DUF1751 PF08551.10 CCU98903.1 - 7.5e-06 26.4 0.4 1.2e-05 25.8 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) SLAC1 PF03595.17 CCU98904.1 - 6.4e-82 275.4 40.1 7.2e-82 275.2 40.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel WD40 PF00400.32 CCU98905.1 - 4.5e-41 138.1 14.1 3.6e-06 27.6 0.0 8.4 7 2 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU98905.1 - 7.1e-23 80.7 0.0 6.8e-05 23.1 0.1 7.0 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCU98905.1 - 9.7e-06 24.5 1.0 0.0024 16.6 0.0 3.6 3 1 2 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CCU98905.1 - 2.1e-05 24.5 0.0 0.00093 19.1 0.0 3.0 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCU98905.1 - 0.013 14.5 0.0 1.5 7.7 0.0 2.8 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_S7 PF00177.21 CCU98906.1 - 1.8e-36 125.0 0.8 2.3e-36 124.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CtaG_Cox11 PF04442.14 CCU98907.1 - 4.4e-57 192.4 0.1 5.2e-57 192.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DKCLD PF08068.12 CCU98908.1 - 3.9e-32 110.1 0.1 3.7e-31 107.0 0.2 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 CCU98908.1 - 1.7e-23 82.5 0.5 3.3e-23 81.6 0.5 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 CCU98908.1 - 3.4e-22 79.4 6.2 7.7e-21 75.0 0.2 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 CCU98908.1 - 3.4e-21 75.0 0.7 7.1e-21 74.0 0.7 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 CCU98908.1 - 0.0049 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain YL1 PF05764.13 CCU98908.1 - 0.44 10.6 33.9 0.64 10.1 33.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Ribosomal_L22e PF01776.17 CCU98909.1 - 3.8e-44 149.5 0.0 4.7e-44 149.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family MH2 PF03166.14 CCU98909.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 MH2 domain Spb1_C PF07780.12 CCU98910.1 - 9.1e-78 260.7 16.9 9.1e-78 260.7 16.9 3.1 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 CCU98910.1 - 4.1e-56 189.9 0.0 7.9e-56 189.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CCU98910.1 - 1.8e-46 157.9 8.0 1.8e-46 157.9 8.0 5.7 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) eIF2A PF08662.11 CCU98911.1 - 1.4e-39 136.0 0.3 2e-35 122.5 0.1 4.0 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CCU98911.1 - 0.00035 20.3 0.0 0.00096 18.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3105 PF11303.8 CCU98911.1 - 0.023 14.8 0.2 0.093 12.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3105) WD40 PF00400.32 CCU98911.1 - 0.027 15.4 2.3 1.7 9.6 0.2 4.6 6 0 0 6 6 6 0 WD domain, G-beta repeat Spt5-NGN PF03439.13 CCU98911.1 - 0.057 13.3 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section CHAD PF05235.14 CCU98911.1 - 0.12 12.3 3.3 0.28 11.1 3.3 1.5 1 0 0 1 1 1 0 CHAD domain PEX11 PF05648.14 CCU98912.1 - 1.7e-64 217.3 2.4 2e-64 217.1 2.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DGCR6 PF07324.11 CCU98912.1 - 0.016 14.8 0.1 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein DUF1839 PF08893.10 CCU98912.1 - 0.14 11.3 1.3 0.48 9.5 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1839) Sel1 PF08238.12 CCU98913.1 - 0.00035 21.2 15.8 0.12 13.1 0.3 5.4 4 1 0 4 4 4 3 Sel1 repeat Ribosomal_L32p PF01783.23 CCU98914.1 - 0.00039 20.6 2.3 0.00068 19.8 2.1 1.5 2 0 0 2 2 2 1 Ribosomal L32p protein family ICL PF00463.21 CCU98915.1 - 5.3e-268 889.8 2.8 6e-268 889.6 2.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CCU98915.1 - 8.4e-09 35.2 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Ribo_biogen_C PF04034.13 CCU98916.1 - 2.4e-48 163.1 0.0 3.2e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CCU98916.1 - 8e-13 48.0 0.2 1.4e-12 47.2 0.2 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Prenyltrans PF00432.21 CCU98918.1 - 1.2e-54 181.7 10.5 9.7e-10 38.0 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CCU98918.1 - 4e-07 29.4 0.1 2.5e-06 26.8 0.0 2.1 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CCU98918.1 - 0.00063 18.9 0.1 0.051 12.7 0.0 2.9 2 1 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain MutS_V PF00488.21 CCU98919.1 - 9.3e-62 208.4 0.4 2.1e-61 207.3 0.4 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CCU98919.1 - 2.8e-28 99.5 2.0 6.4e-28 98.3 2.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CCU98919.1 - 1.3e-22 80.2 0.0 8.5e-22 77.5 0.0 2.3 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 CCU98919.1 - 1.4e-06 28.6 0.0 3.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 CCU98919.1 - 7.9e-05 22.9 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 MutS family domain IV RNA_pol_Rpb6 PF01192.22 CCU98920.1 - 1.8e-09 37.4 0.3 3e-09 36.7 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 AMP-binding PF00501.28 CCU98921.1 - 3.9e-51 174.0 0.0 5.8e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CCU98921.1 - 6.2e-11 42.5 1.6 1.8e-10 41.0 1.6 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 CCU98921.1 - 5.2e-08 32.3 3.8 0.1 12.4 0.1 6.6 7 1 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 CCU98921.1 - 1.6e-06 29.0 0.0 0.011 16.7 0.0 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain GH3 PF03321.13 CCU98921.1 - 0.013 14.4 0.0 0.4 9.5 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Hexapep_2 PF14602.6 CCU98921.1 - 1.6 8.6 10.3 2.3 8.0 0.1 5.2 6 1 1 7 7 7 0 Hexapeptide repeat of succinyl-transferase Hepar_II_III PF07940.13 CCU98922.1 - 3.3e-09 36.7 0.0 6.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Heparinase II/III-like protein DUF4962 PF16332.5 CCU98922.1 - 1.8e-06 26.8 4.7 3.3e-06 25.9 4.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4962) Carn_acyltransf PF00755.20 CCU98924.1 - 1.8e-182 608.1 0.0 2e-182 607.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase tRNA-synt_2 PF00152.20 CCU98926.1 - 1.6e-77 260.7 0.1 2.1e-77 260.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCU98926.1 - 0.00024 21.1 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCU98926.1 - 0.075 12.5 0.2 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Tubulin PF00091.25 CCU98927.1 - 8e-65 218.7 0.0 1.1e-64 218.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CCU98927.1 - 2.2e-36 124.8 0.1 3.2e-36 124.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CCU98927.1 - 5.1e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CCU98927.1 - 0.0032 17.2 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CCU98927.1 - 0.0034 16.6 0.1 0.013 14.7 0.0 1.9 3 0 0 3 3 3 1 Tubulin like Cupin_8 PF13621.6 CCU98928.1 - 1.9e-15 57.3 0.0 1.7e-10 41.1 0.0 2.1 2 0 0 2 2 2 2 Cupin-like domain JmjC PF02373.22 CCU98928.1 - 2.1e-11 44.2 0.0 4.3e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 CCU98928.1 - 0.0047 16.4 0.0 0.0086 15.6 0.0 1.5 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 CCU98928.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Cupin_1 PF00190.22 CCU98928.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Cupin RhoGEF PF00621.20 CCU98929.1 - 1.1e-35 123.6 0.0 1.6e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain TLD PF07534.16 CCU98929.1 - 3.9e-21 75.7 0.0 1.5e-19 70.6 0.0 2.7 2 1 0 2 2 2 1 TLD LRR_8 PF13855.6 CCU98929.1 - 3e-08 33.3 1.4 0.00053 19.7 0.2 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CCU98929.1 - 9.9e-07 29.0 0.3 0.014 15.8 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CCU98929.1 - 0.045 14.3 2.3 5.4 8.0 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 CCU98929.1 - 0.32 11.2 3.6 4.5 7.6 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeat MMS1_N PF10433.9 CCU98930.1 - 3.6e-144 481.0 0.0 6.4e-144 480.2 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CCU98930.1 - 2.7e-84 283.3 0.0 1.6e-83 280.7 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region AdoMet_MTase PF07757.13 CCU98931.1 - 1.1e-29 103.0 0.1 1.8e-28 99.1 0.1 2.4 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 CCU98931.1 - 0.0069 16.4 0.0 0.026 14.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Tma16 PF11176.8 CCU98933.1 - 8.6e-37 126.2 0.2 1e-36 126.0 0.2 1.0 1 0 0 1 1 1 1 Translation machinery-associated protein 16 ADH_zinc_N PF00107.26 CCU98934.1 - 9.5e-17 61.2 0.8 1.6e-16 60.5 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCU98934.1 - 7.9e-07 30.2 1.1 4e-06 27.9 0.1 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.10 CCU98934.1 - 0.027 14.6 0.2 0.077 13.2 0.2 1.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Trp_oprn_chp PF09534.10 CCU98935.1 - 0.069 12.9 6.8 3.7 7.3 6.8 2.3 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Holin_SPP1 PF04688.13 CCU98935.1 - 0.22 11.7 1.2 0.56 10.4 1.2 1.7 1 0 0 1 1 1 0 SPP1 phage holin Tetraspanin PF00335.20 CCU98935.1 - 7.8 6.1 10.5 2.4 7.8 6.7 1.9 2 0 0 2 2 2 0 Tetraspanin family Myb_DNA-bind_7 PF15963.5 CCU98936.1 - 3.9e-27 94.0 1.6 9.9e-27 92.7 1.6 1.6 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CCU98936.1 - 2.1e-08 34.2 0.8 4.4e-08 33.2 0.8 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCU98936.1 - 0.034 14.4 1.1 0.074 13.3 1.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Nif11 PF07862.11 CCU98936.1 - 0.06 13.6 0.1 20 5.6 0.0 2.5 2 0 0 2 2 2 0 Nif11 domain HeLo PF14479.6 CCU98936.1 - 1.5 8.6 7.1 0.25 11.1 2.7 1.8 2 0 0 2 2 2 0 Prion-inhibition and propagation Bud13 PF09736.9 CCU98937.1 - 8.6e-46 155.9 5.4 8.6e-46 155.9 5.4 2.4 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex BNIP3 PF06553.12 CCU98937.1 - 0.14 11.8 3.2 0.25 11.0 3.1 1.4 1 1 0 1 1 1 0 BNIP3 zf-Nse PF11789.8 CCU98938.1 - 1.1e-13 50.8 0.0 1.8e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 CCU98938.1 - 0.00013 22.0 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.6 CCU98938.1 - 0.00096 19.1 0.0 0.002 18.1 0.0 1.6 1 1 0 1 1 1 1 RING-type zinc-finger AcylCoA_dehyd_C PF12186.8 CCU98938.1 - 0.0071 16.5 0.7 2.7 8.1 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase C terminal Rtf2 PF04641.12 CCU98938.1 - 0.017 14.5 0.1 0.054 12.9 0.0 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 CCU98938.1 - 0.052 13.4 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Seryl_tRNA_N PF02403.22 CCU98938.1 - 0.4 10.9 4.7 0.36 11.1 1.3 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CTP_synth_N PF06418.14 CCU98940.1 - 1.4e-119 398.3 0.0 1.9e-119 397.9 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CCU98940.1 - 5.4e-50 169.8 0.0 8.7e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CCU98940.1 - 0.024 14.4 0.1 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Peptidase C26 CbiA PF01656.23 CCU98940.1 - 0.089 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Steroid_dh PF02544.16 CCU98941.1 - 2.7e-14 53.4 0.7 3.8e-12 46.4 0.7 2.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase SNF2_N PF00176.23 CCU98942.1 - 1.7e-63 214.4 0.5 3.2e-63 213.6 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 CCU98942.1 - 2.3e-51 173.6 15.9 2.3e-51 173.6 15.9 2.5 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 CCU98942.1 - 7.4e-17 61.7 0.0 1.7e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU98942.1 - 2.7e-06 27.5 0.0 7.5e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCU98942.1 - 0.0056 16.5 0.0 0.034 13.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 CCU98942.1 - 0.015 14.5 2.9 0.041 13.0 0.0 2.8 3 1 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 YCII PF03795.14 CCU98942.1 - 0.064 13.7 1.4 0.31 11.5 0.0 3.0 3 0 0 3 3 3 0 YCII-related domain Fe_hyd_lg_C PF02906.14 CCU98942.1 - 0.12 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Pex14_N PF04695.13 CCU98943.1 - 1.4e-14 55.0 10.5 1.9e-14 54.6 0.2 2.3 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.14 CCU98943.1 - 0.27 9.5 1.2 0.45 8.8 1.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Rep_4 PF05797.11 CCU98943.1 - 0.4 9.8 4.5 0.61 9.2 4.5 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) RNA_pol_Rpc4 PF05132.14 CCU98943.1 - 6.3 7.2 6.0 0.64 10.4 1.3 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 DNA_pol_phi PF04931.13 CCU98943.1 - 9.6 4.2 8.6 14 3.6 8.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_S28e PF01200.18 CCU98944.1 - 4.3e-31 106.7 0.9 4.9e-31 106.5 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 CCU98944.1 - 0.095 13.0 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Adaptin_N PF01602.20 CCU98945.1 - 7.2e-112 374.6 0.0 9.7e-112 374.2 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CCU98945.1 - 3.7e-46 157.0 0.0 9.3e-46 155.7 0.0 1.7 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CCU98945.1 - 4.1e-29 101.0 0.0 9.5e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CCU98945.1 - 2.3e-19 69.6 2.2 9.5e-10 38.7 0.1 5.3 3 1 2 5 5 5 4 HEAT repeats Cnd1 PF12717.7 CCU98945.1 - 4.2e-08 33.4 3.4 0.071 13.2 0.2 3.7 3 1 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CCU98945.1 - 3.9e-05 23.5 5.6 1.8 9.1 0.2 6.1 6 0 0 6 6 6 1 HEAT repeat Arm PF00514.23 CCU98945.1 - 0.0014 18.6 2.9 11 6.2 0.0 5.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 CCU98945.1 - 0.0039 17.7 9.6 5.4 8.0 0.2 6.2 6 1 0 6 6 6 2 PBS lyase HEAT-like repeat DUF3385 PF11865.8 CCU98945.1 - 0.13 12.1 0.0 3.4 7.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) bZIP_2 PF07716.15 CCU98946.1 - 1.9e-10 40.6 15.1 1.9e-10 40.6 15.1 2.3 2 0 0 2 2 2 1 Basic region leucine zipper DUF2205 PF10224.9 CCU98946.1 - 0.0076 16.2 1.9 0.0076 16.2 1.9 1.7 2 0 0 2 2 2 1 Short coiled-coil protein PRKG1_interact PF15898.5 CCU98946.1 - 0.02 15.8 7.9 0.02 15.8 7.9 2.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain bZIP_Maf PF03131.17 CCU98946.1 - 0.021 15.4 8.2 0.021 15.4 8.2 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor TSC22 PF01166.18 CCU98946.1 - 0.022 15.1 0.5 0.047 14.0 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family NRBF2 PF08961.10 CCU98946.1 - 0.023 14.3 1.2 0.023 14.3 1.2 2.2 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 CCU98946.1 - 0.029 14.5 14.6 0.05 13.7 13.6 1.9 1 1 1 2 2 2 0 bZIP transcription factor YabA PF06156.13 CCU98946.1 - 0.041 14.5 2.9 0.069 13.8 2.0 1.8 1 1 0 1 1 1 0 Initiation control protein YabA Shugoshin_N PF07558.11 CCU98946.1 - 0.099 12.5 3.4 0.21 11.5 3.4 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region KAsynt_C_assoc PF16197.5 CCU98946.1 - 0.16 12.5 0.2 0.51 10.8 0.0 1.9 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension Phlebovirus_NSM PF07246.11 CCU98946.1 - 0.2 11.0 1.8 0.3 10.4 1.8 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DivIC PF04977.15 CCU98946.1 - 0.42 10.4 2.8 0.57 10.0 1.8 1.7 1 1 0 1 1 1 0 Septum formation initiator Macoilin PF09726.9 CCU98946.1 - 4.7 5.7 7.2 0.22 10.1 1.4 1.5 2 0 0 2 2 2 0 Macoilin family Sugar_tr PF00083.24 CCU98947.1 - 8.6e-93 311.6 25.8 7.9e-91 305.2 25.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCU98947.1 - 2.6e-12 46.4 38.4 4.2e-09 35.8 18.3 3.9 2 1 0 3 3 3 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 CCU98947.1 - 0.55 10.0 4.4 0.43 10.4 1.1 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2530 PF10745.9 CCU98947.1 - 1.1 9.5 7.3 1.1 9.6 2.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF697 PF05128.12 CCU98947.1 - 3.6 7.3 5.2 12 5.6 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF697) MFS_1 PF07690.16 CCU98948.1 - 2.9e-12 46.2 51.8 3e-11 42.9 49.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1980 PF09323.10 CCU98948.1 - 7.9 6.3 6.7 9.9 6.0 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) ParA PF10609.9 CCU98949.1 - 7.1e-76 254.9 0.0 1.6e-75 253.8 0.0 1.5 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CCU98949.1 - 4.2e-08 33.3 0.0 1.6e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CCU98949.1 - 3.1e-07 30.5 2.3 3.7e-05 23.7 0.4 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CCU98949.1 - 0.00061 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 CCU98949.1 - 0.0066 15.8 0.8 0.0079 15.5 0.1 1.4 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 CCU98949.1 - 0.0082 15.3 1.5 0.0082 15.3 1.5 1.8 2 1 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 CCU98949.1 - 0.018 14.5 0.2 0.093 12.2 0.2 1.9 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 CCU98949.1 - 0.064 13.1 0.7 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain FAD_binding_2 PF00890.24 CCU98950.1 - 8.8e-126 420.3 4.3 1.2e-125 419.9 4.3 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CCU98950.1 - 6.6e-42 142.5 1.2 9.8e-42 142.0 1.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 CCU98950.1 - 0.0001 21.6 1.5 0.043 12.9 2.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 CCU98950.1 - 0.00017 20.9 0.5 0.048 12.9 0.2 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 CCU98950.1 - 0.00031 20.1 0.9 0.0042 16.3 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CCU98950.1 - 0.013 14.6 0.1 0.048 12.7 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 CCU98950.1 - 0.02 14.2 1.2 0.024 13.9 0.3 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 CCU98950.1 - 0.48 9.1 4.4 0.83 8.3 1.0 2.8 3 0 0 3 3 3 0 HI0933-like protein zf-C2HC5 PF06221.13 CCU98952.1 - 3.4e-15 55.8 5.0 5.6e-15 55.1 5.0 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Herpes_pp85 PF04637.12 CCU98952.1 - 0.32 9.3 0.9 0.6 8.5 0.9 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Cupin_8 PF13621.6 CCU98953.1 - 3.6e-07 30.2 0.0 2.1e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain PHD PF00628.29 CCU98953.1 - 5.7e-07 29.3 8.8 1.2e-06 28.3 8.8 1.6 1 0 0 1 1 1 1 PHD-finger JmjC PF02373.22 CCU98953.1 - 1.1e-06 29.0 0.3 2.8e-05 24.5 0.1 2.6 2 1 0 2 2 2 1 JmjC domain, hydroxylase PHD_2 PF13831.6 CCU98953.1 - 0.001 18.6 6.2 0.0023 17.5 6.2 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 CCU98953.1 - 0.01 15.7 2.5 0.021 14.7 2.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 CCU98953.1 - 0.047 14.0 0.3 0.047 14.0 0.3 1.8 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CCU98953.1 - 0.081 13.1 0.6 0.081 13.1 0.6 1.9 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-CW PF07496.15 CCU98953.1 - 0.37 10.9 4.6 0.96 9.5 4.6 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger zf-RING_2 PF13639.6 CCU98953.1 - 0.95 9.9 5.9 2.5 8.5 5.9 1.8 1 0 0 1 1 1 0 Ring finger domain efThoc1 PF11957.8 CCU98954.1 - 6.7e-64 216.3 0.0 9.6e-31 107.0 0.0 2.8 3 1 0 3 3 3 2 THO complex subunit 1 transcription elongation factor Ribosomal_S27 PF01599.19 CCU98956.1 - 3.6e-26 91.1 0.7 4.1e-26 90.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27a IBR PF01485.21 CCU98956.1 - 0.015 15.5 1.1 0.022 15.0 1.1 1.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Pkinase PF00069.25 CCU98957.1 - 2.2e-50 171.5 0.0 2.9e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU98957.1 - 3.5e-20 72.4 0.0 6.1e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L2_C PF03947.18 CCU98959.1 - 7.3e-50 168.4 2.6 8.7e-50 168.1 0.6 2.1 3 0 0 3 3 3 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CCU98959.1 - 2.1e-25 88.5 0.1 4.6e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Skp1 PF01466.19 CCU98960.1 - 7.5e-26 90.0 0.3 7.5e-26 90.0 0.3 1.7 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CCU98960.1 - 3.5e-25 87.9 0.2 1e-24 86.4 0.1 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 CCU98960.1 - 0.007 16.6 0.1 0.15 12.3 0.1 2.2 1 1 0 1 1 1 1 BTB/POZ domain G-patch PF01585.23 CCU98962.1 - 1.5e-11 44.0 3.8 4.1e-11 42.6 3.8 1.8 1 0 0 1 1 1 1 G-patch domain DUF936 PF06075.12 CCU98962.1 - 0.007 15.3 13.7 0.0071 15.3 13.7 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) G-patch_2 PF12656.7 CCU98962.1 - 0.033 14.3 1.9 0.033 14.3 1.9 3.5 2 1 0 2 2 1 0 G-patch domain RR_TM4-6 PF06459.12 CCU98962.1 - 0.034 14.0 20.9 0.056 13.3 20.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 CCU98962.1 - 0.074 11.8 8.7 0.086 11.6 8.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 CCU98962.1 - 0.19 10.7 13.3 0.26 10.3 13.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Vfa1 PF08432.10 CCU98962.1 - 0.23 11.7 26.7 0.45 10.8 26.7 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 CCU98962.1 - 0.29 9.8 16.8 0.41 9.3 16.8 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CCU98962.1 - 0.31 11.0 6.3 0.39 10.7 6.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 CCU98962.1 - 0.32 9.8 17.0 0.46 9.2 17.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.14 CCU98962.1 - 0.33 9.2 19.8 0.41 8.9 19.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1943 PF09172.11 CCU98962.1 - 0.37 10.0 5.3 0.5 9.6 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) FAM60A PF15396.6 CCU98962.1 - 0.39 10.7 18.7 0.59 10.1 18.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A AAA_11 PF13086.6 CCU98962.1 - 0.61 9.8 13.8 1 9.1 13.8 1.3 1 0 0 1 1 1 0 AAA domain DUF4770 PF15994.5 CCU98962.1 - 1.1 9.4 13.7 1.9 8.7 13.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) TFIIF_alpha PF05793.12 CCU98962.1 - 1.3 7.6 34.6 1.8 7.0 34.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-N PF05238.13 CCU98962.1 - 1.6 8.0 14.3 2.2 7.5 14.3 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Zip PF02535.22 CCU98962.1 - 1.7 7.8 9.4 2.3 7.3 9.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter VIR_N PF15912.5 CCU98962.1 - 3.7 7.1 17.1 5.6 6.5 17.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal NPR3 PF03666.13 CCU98962.1 - 4.2 6.0 23.3 5.9 5.6 23.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 CCU98962.1 - 4.3 5.3 15.1 5.6 5.0 15.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec62 PF03839.16 CCU98962.1 - 5.4 6.4 21.1 8.3 5.9 21.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Endostatin PF06482.11 CCU98962.1 - 9.5 5.6 9.4 15 5.0 9.4 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PPL5 PF18168.1 CCU98962.1 - 9.6 5.4 15.8 18 4.5 15.8 1.5 1 0 0 1 1 1 0 Prim-pol family 5 polyprenyl_synt PF00348.17 CCU98963.1 - 3.2e-94 314.7 0.1 4.2e-94 314.4 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CN_hydrolase PF00795.22 CCU98964.1 - 1.2e-52 178.9 0.0 2.6e-52 177.7 0.0 1.5 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_S24 PF00717.23 CCU98965.1 - 2.5e-06 27.3 0.1 0.00026 20.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.9 CCU98965.1 - 0.072 12.9 0.0 8.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 Metallophos PF00149.28 CCU98966.1 - 4e-06 27.5 1.8 4e-06 27.5 1.8 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Fer2 PF00111.27 CCU98966.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain ICL PF00463.21 CCU98967.1 - 1.5e-178 594.6 0.0 1.8e-178 594.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CCU98967.1 - 1.5e-08 34.4 0.1 5e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase RNA_pol_Rpc4 PF05132.14 CCU98968.1 - 1.4e-19 71.0 0.0 1.4e-19 71.0 0.0 4.2 2 2 1 3 3 3 2 RNA polymerase III RPC4 DUF2408 PF10303.9 CCU98969.1 - 1.4e-47 161.6 6.6 8.3e-35 120.3 0.1 4.9 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) FUSC PF04632.12 CCU98969.1 - 0.18 10.3 3.4 0.2 10.1 0.6 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF1664 PF07889.12 CCU98969.1 - 0.3 11.1 7.6 0.45 10.6 0.6 3.6 6 0 0 6 6 6 0 Protein of unknown function (DUF1664) Sas10_Utp3 PF04000.15 CCU98969.1 - 0.57 10.8 3.9 18 6.1 0.1 4.5 3 2 0 3 3 3 0 Sas10/Utp3/C1D family Laminin_II PF06009.12 CCU98969.1 - 4.8 7.2 11.4 6.6 6.7 1.2 4.6 4 1 1 5 5 5 0 Laminin Domain II ABC_tran_CTD PF16326.5 CCU98969.1 - 7.8 6.8 11.2 13 6.1 0.6 4.2 3 1 1 4 4 4 0 ABC transporter C-terminal domain Bax1-I PF01027.20 CCU98970.1 - 2.8e-37 128.6 6.0 3.9e-37 128.1 6.0 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Profilin PF00235.19 CCU98971.1 - 1.4e-47 161.1 0.0 1.5e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Profilin TIM PF00121.18 CCU98972.1 - 1.6e-94 315.8 0.3 1.9e-94 315.6 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Spo12 PF05032.12 CCU98973.1 - 1.7e-11 43.8 2.9 3.2e-11 42.9 2.9 1.5 1 0 0 1 1 1 1 Spo12 family SnoaL_2 PF12680.7 CCU98973.1 - 0.0014 19.2 0.1 0.0034 18.0 0.0 1.7 1 1 1 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 CCU98973.1 - 0.088 13.2 0.0 0.15 12.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) AICARFT_IMPCHas PF01808.18 CCU98974.1 - 1.9e-87 293.5 0.1 2.6e-87 293.0 0.1 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CCU98974.1 - 4.6e-21 74.8 0.0 8.3e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Ribosomal_S11 PF00411.19 CCU98974.1 - 0.02 15.3 0.5 0.098 13.1 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S11 TetR_C_11 PF16859.5 CCU98974.1 - 2.6 8.4 7.0 1.2 9.5 0.1 3.5 4 1 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Mon1 PF03164.14 CCU98975.1 - 3.6e-47 161.3 0.0 4.8e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 LIAS_N PF16881.5 CCU98976.1 - 5.7e-17 62.1 0.0 1.9e-16 60.4 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CCU98976.1 - 2.7e-12 47.4 0.0 4.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily ATP_bind_1 PF03029.17 CCU98977.1 - 1.3e-68 231.4 0.1 8.2e-62 209.1 0.0 2.2 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CCU98977.1 - 7e-07 29.0 0.0 8.3e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 CCU98977.1 - 6.9e-05 23.0 0.7 0.0002 21.5 0.0 2.1 2 2 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CCU98977.1 - 0.00011 22.3 0.0 0.0025 17.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 CCU98977.1 - 0.00018 20.6 0.1 0.02 13.9 0.1 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 CCU98977.1 - 0.00021 21.3 0.0 0.17 11.8 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 CCU98977.1 - 0.00036 20.1 0.1 0.0034 16.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.19 CCU98977.1 - 0.00047 19.8 0.0 0.55 9.8 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CCU98977.1 - 0.0013 18.7 0.6 0.0021 18.0 0.1 1.6 2 0 0 2 2 1 1 NACHT domain AAA_16 PF13191.6 CCU98977.1 - 0.0013 19.1 1.9 0.0023 18.3 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCU98977.1 - 0.0016 18.7 0.0 0.0058 16.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 CCU98977.1 - 0.0019 17.9 0.4 0.013 15.1 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 CCU98977.1 - 0.0078 16.8 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CCU98977.1 - 0.011 15.3 2.1 0.15 11.6 2.1 2.7 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CCU98977.1 - 0.013 15.4 0.0 0.67 9.8 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 CCU98977.1 - 0.019 14.7 0.1 0.071 12.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CCU98977.1 - 0.035 13.8 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CCU98977.1 - 0.039 13.7 0.7 0.039 13.7 0.7 1.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CCU98977.1 - 0.05 12.9 0.3 0.5 9.7 0.1 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_19 PF13245.6 CCU98977.1 - 0.059 13.7 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCU98977.1 - 0.063 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.21 CCU98977.1 - 0.08 12.4 0.0 17 4.8 0.0 2.6 3 0 0 3 3 3 0 ADP-ribosylation factor family RNA_helicase PF00910.22 CCU98977.1 - 0.084 13.3 0.0 0.36 11.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 CCU98977.1 - 0.085 12.0 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.17 CCU98977.1 - 0.12 12.4 1.0 0.18 11.9 0.2 1.6 2 0 0 2 2 1 0 Helicase HerA, central domain AAA_5 PF07728.14 CCU98977.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 CCU98977.1 - 0.2 12.1 1.0 0.7 10.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain ADH_N PF08240.12 CCU98978.1 - 8e-22 77.2 0.8 1.5e-21 76.3 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCU98978.1 - 2.6e-13 50.1 0.0 5.3e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CCU98978.1 - 0.00024 20.5 0.1 0.00038 19.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 CCU98978.1 - 0.004 16.6 0.9 0.0063 15.9 0.9 1.3 1 0 0 1 1 1 1 ThiF family ApbA PF02558.16 CCU98978.1 - 0.0046 16.6 0.0 0.0098 15.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 CCU98978.1 - 0.014 14.7 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 CCU98978.1 - 0.02 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CCU98978.1 - 0.037 14.1 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CCU98978.1 - 0.045 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Hydrolase PF00702.26 CCU98978.1 - 0.18 12.1 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF202 PF02656.15 CCU98979.1 - 1e-17 64.3 1.0 1.5e-17 63.8 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF202) COX17 PF05051.13 CCU98980.1 - 5.5e-20 71.5 4.5 8.9e-20 70.8 4.5 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 CCU98980.1 - 0.0056 16.9 0.5 0.0074 16.5 0.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Ribosomal_60s PF00428.19 CCU98981.1 - 1.7e-27 95.8 10.3 2.2e-27 95.5 10.3 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 CCU98981.1 - 0.067 13.9 3.2 0.12 13.1 3.2 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Cytomega_UL84 PF06284.11 CCU98981.1 - 0.89 7.9 2.3 1.2 7.5 2.3 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Trehalase PF01204.18 CCU98982.1 - 1.7e-164 548.4 0.3 2.2e-164 548.1 0.3 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CCU98982.1 - 1.1e-13 50.7 1.6 2e-13 49.8 1.6 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain CAP PF00188.26 CCU98982.1 - 0.011 16.5 0.0 0.05 14.4 0.0 2.0 3 0 0 3 3 3 0 Cysteine-rich secretory protein family ALS_ss_C PF10369.9 CCU98983.1 - 8.7e-18 64.3 0.0 1.6e-15 57.1 0.0 2.6 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 CCU98983.1 - 1e-10 41.2 0.0 1.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 CCU98983.1 - 9.7e-07 28.5 0.2 1.1e-05 25.1 0.0 2.4 3 0 0 3 3 3 1 ACT domain ACT_6 PF13740.6 CCU98983.1 - 0.14 12.2 0.1 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 ACT domain ACT_7 PF13840.6 CCU98983.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 ACT domain DASH_Dad4 PF08650.10 CCU98984.1 - 0.0012 18.8 0.1 0.0026 17.7 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Dad4 Form-deh_trans PF09163.11 CCU98984.1 - 1 9.2 4.1 2.5 8.0 4.1 1.6 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Ribosomal_S21 PF01165.20 CCU98985.1 - 1.5e-08 34.2 7.9 3.3e-08 33.1 7.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 Rot1 PF10681.9 CCU98986.1 - 2.9e-08 33.5 6.6 4.6e-06 26.3 0.7 2.2 1 1 1 2 2 2 2 Chaperone for protein-folding within the ER, fungal NAT PF04768.13 CCU98987.1 - 1.8e-28 99.3 0.0 2.5e-17 63.1 0.0 2.3 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase MBOAT PF03062.19 CCU98988.1 - 1e-37 130.3 21.0 1.5e-37 129.8 21.0 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Clat_adaptor_s PF01217.20 CCU98989.1 - 1.1e-47 161.5 0.5 1.5e-47 161.1 0.5 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pcc1 PF09341.10 CCU98990.1 - 1.9e-19 69.5 0.3 2.5e-19 69.2 0.3 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 PIF1 PF05970.14 CCU98991.1 - 8e-60 202.9 0.0 3.4e-47 161.4 0.1 2.1 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CCU98991.1 - 4.2e-23 82.1 0.0 7.7e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCU98991.1 - 3e-10 40.6 0.0 8.1e-10 39.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 CCU98991.1 - 3.5e-06 27.3 0.0 9.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCU98991.1 - 2.7e-05 24.6 0.5 0.00037 20.9 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 CCU98991.1 - 0.00043 20.2 0.0 0.68 9.8 0.0 2.3 2 0 0 2 2 2 2 NTPase Viral_helicase1 PF01443.18 CCU98991.1 - 0.00048 19.9 0.1 0.0078 16.0 0.0 2.5 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 CCU98991.1 - 0.00073 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 CCU98991.1 - 0.002 18.1 0.0 0.0079 16.1 0.0 1.9 2 0 0 2 2 2 1 NACHT domain DUF2075 PF09848.9 CCU98991.1 - 0.0033 16.7 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 CCU98991.1 - 0.0046 16.8 0.1 0.7 9.6 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_5 PF07728.14 CCU98991.1 - 0.013 15.5 0.1 0.1 12.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CCU98991.1 - 0.014 15.8 0.1 0.035 14.5 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 CCU98991.1 - 0.016 15.2 0.0 0.16 11.8 0.0 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CCU98991.1 - 0.016 15.2 0.0 0.052 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CCU98991.1 - 0.016 15.7 0.0 0.058 13.9 0.0 1.9 2 0 0 2 2 1 0 ABC transporter IstB_IS21 PF01695.17 CCU98991.1 - 0.017 14.9 0.0 0.9 9.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CCU98991.1 - 0.02 15.3 0.0 0.044 14.2 0.0 1.7 1 1 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 CCU98991.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 CCU98991.1 - 0.041 13.9 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 CCU98991.1 - 0.045 13.5 0.1 5 6.8 0.0 2.3 1 1 0 2 2 2 0 AAA domain MeaB PF03308.16 CCU98991.1 - 0.06 12.3 0.1 0.095 11.7 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TniB PF05621.11 CCU98991.1 - 0.093 12.1 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 Bacterial TniB protein SH3_13 PF18335.1 CCU98991.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Helicase_RecD PF05127.14 CCU98991.1 - 0.11 12.3 0.4 0.34 10.8 0.4 1.8 1 1 0 1 1 1 0 Helicase Mg_chelatase PF01078.21 CCU98991.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 CCU98991.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_32 PF13654.6 CCU98991.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CCU98991.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TrwB_AAD_bind PF10412.9 CCU98991.1 - 0.14 11.0 0.2 0.41 9.5 0.1 1.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 CCU98991.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 CCU98991.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin IF-2B PF01008.17 CCU98992.1 - 2.1e-53 181.4 0.1 7.2e-53 179.6 0.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF2013 PF09431.10 CCU98993.1 - 1.1e-37 129.3 0.5 1.6e-37 128.8 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Rcd1 PF04078.13 CCU98993.1 - 0.043 13.1 1.2 0.045 13.0 0.2 1.5 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like ORC4_C PF14629.6 CCU98994.1 - 3.8e-30 104.9 0.2 7.9e-30 103.9 0.0 1.6 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 CCU98994.1 - 1.4e-06 28.8 1.2 2.3e-06 28.1 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain PAXNEB PF05625.11 CCU98995.1 - 3.6e-37 128.4 0.0 3.4e-36 125.2 0.0 2.3 1 1 0 1 1 1 1 PAXNEB protein Imm58 PF15581.6 CCU98995.1 - 0.029 14.5 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 58 AAA PF00004.29 CCU98996.1 - 1.1e-43 148.9 0.0 2.1e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCU98996.1 - 5.2e-11 42.2 0.1 1.1e-10 41.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CCU98996.1 - 2.5e-08 33.8 0.6 6.4e-08 32.4 0.6 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CCU98996.1 - 8.2e-08 32.5 0.0 1.8e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCU98996.1 - 2.8e-06 27.4 0.0 1.2e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCU98996.1 - 7.6e-06 26.4 0.0 9.3e-05 22.9 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCU98996.1 - 1.4e-05 25.4 0.4 0.0069 16.7 0.1 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CCU98996.1 - 6e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CCU98996.1 - 0.001 18.4 0.0 0.0022 17.2 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CCU98996.1 - 0.0017 18.6 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCU98996.1 - 0.0018 18.8 0.7 0.016 15.7 0.0 2.5 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 CCU98996.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 CCU98996.1 - 0.005 16.3 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.11 CCU98996.1 - 0.0057 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CCU98996.1 - 0.01 15.3 0.1 0.02 14.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CCU98996.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CCU98996.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 CCU98996.1 - 0.014 14.7 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 CCU98996.1 - 0.015 15.1 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CCU98996.1 - 0.024 14.4 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CCU98996.1 - 0.027 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 CCU98996.1 - 0.033 13.3 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 CCU98996.1 - 0.037 13.1 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 CCU98996.1 - 0.037 14.3 0.1 0.073 13.3 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_14 PF13173.6 CCU98996.1 - 0.04 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CCU98996.1 - 0.044 14.2 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 CCU98996.1 - 0.057 13.0 0.1 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CCU98996.1 - 0.065 13.0 0.2 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CCU98996.1 - 0.086 12.5 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CCU98996.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 CCU98996.1 - 0.12 12.8 0.1 0.37 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 CCU98996.1 - 0.12 12.3 0.0 0.71 9.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain AAA_19 PF13245.6 CCU98996.1 - 0.13 12.6 0.1 0.61 10.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain TPR_11 PF13414.6 CCU98997.1 - 0.002 17.8 0.0 1.4 8.7 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 CCU98997.1 - 0.0054 17.0 0.4 0.092 13.2 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCU98997.1 - 0.012 15.6 3.1 0.29 11.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCU98997.1 - 0.025 14.4 2.3 9.7 6.2 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCU98997.1 - 0.16 12.5 1.0 28 5.3 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Dus PF01207.17 CCU98998.1 - 1.7e-54 185.0 0.0 2.6e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHHC PF01529.20 CCU98999.1 - 4.9e-36 123.8 4.6 4.9e-36 123.8 4.6 2.7 3 0 0 3 3 3 1 DHHC palmitoyltransferase OAD_gamma PF04277.13 CCU98999.1 - 0.062 13.9 1.0 81 3.9 0.8 3.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain zinc_ribbon_2 PF13240.6 CCU98999.1 - 0.47 10.2 3.5 0.89 9.4 3.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 CCU98999.1 - 0.68 10.0 9.1 1.6 8.8 9.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon CrgA PF06781.12 CCU98999.1 - 1.9 8.6 10.6 0.24 11.5 0.8 3.4 3 1 1 4 4 4 0 Cell division protein CrgA MFS_1 PF07690.16 CCU99000.1 - 1.4e-20 73.5 8.7 7.6e-20 71.1 8.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 CCU99000.1 - 1.5e-20 73.8 6.9 3.6e-20 72.5 6.9 1.6 1 0 0 1 1 1 1 Nodulin-like zf-ZPR1 PF03367.13 CCU99001.1 - 2.1e-108 359.2 0.4 4.3e-53 179.4 0.0 2.9 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 CCU99001.1 - 0.00031 20.7 2.1 0.26 11.3 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CCU99001.1 - 0.0071 16.3 6.4 0.44 10.6 0.2 3.1 2 1 0 2 2 2 2 Double zinc ribbon zinc-ribbons_6 PF07191.12 CCU99001.1 - 0.081 12.9 0.9 13 5.8 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbons OrfB_Zn_ribbon PF07282.11 CCU99001.1 - 0.62 10.0 5.8 9.7 6.2 0.0 3.1 4 0 0 4 4 4 0 Putative transposase DNA-binding domain zf-C2HC5 PF06221.13 CCU99001.1 - 1.2 9.1 6.5 20 5.3 0.1 3.9 4 0 0 4 4 4 0 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.6 CCU99001.1 - 2.4 7.7 17.9 4.4 6.8 0.4 4.4 5 0 0 5 5 5 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 CCU99001.1 - 4.4 7.4 5.5 2 8.5 0.1 2.9 4 0 0 4 4 4 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.6 CCU99001.1 - 5.2 6.9 15.0 1 9.2 0.3 4.4 4 0 0 4 4 4 0 zinc-ribbon domain Lar_restr_allev PF14354.6 CCU99001.1 - 9.6 6.7 8.5 14 6.2 0.3 3.5 3 1 0 3 3 3 0 Restriction alleviation protein Lar Ribosomal_L37e PF01907.19 CCU99001.1 - 10 6.4 6.4 7 6.9 0.1 3.4 4 0 0 4 4 4 0 Ribosomal protein L37e UPF0160 PF03690.13 CCU99002.1 - 3.8e-126 421.0 0.0 4.2e-126 420.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF4841 PF16129.5 CCU99002.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) DUF1604 PF07713.13 CCU99004.1 - 4.1e-40 135.5 1.1 1e-39 134.2 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 CCU99004.1 - 2e-06 27.6 1.2 2e-06 27.6 1.2 1.8 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CCU99004.1 - 0.0064 16.6 2.5 0.019 15.1 0.7 2.7 2 1 0 2 2 2 1 G-patch domain TP_methylase PF00590.20 CCU99005.1 - 8.6e-16 58.5 0.6 6e-15 55.8 0.0 2.2 1 1 1 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases WD40_4 PF16300.5 CCU99006.1 - 1.1e-18 66.8 2.0 4.4e-17 61.7 0.8 2.5 2 0 0 2 2 2 1 Type of WD40 repeat WD40 PF00400.32 CCU99006.1 - 5.3e-10 39.7 3.7 0.046 14.6 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1899 PF08953.11 CCU99006.1 - 1e-06 28.5 0.2 2e-06 27.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 CCU99006.1 - 0.00011 22.5 0.0 1.1 9.5 0.0 3.7 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 CCU99006.1 - 0.00045 19.4 0.0 0.001 18.2 0.0 1.5 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain Nop25 PF09805.9 CCU99007.1 - 9e-17 61.8 11.0 9e-17 61.8 11.0 2.4 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) PNISR PF15996.5 CCU99007.1 - 8.5 6.6 21.0 5.9 7.1 7.6 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR MAT1 PF06391.13 CCU99008.1 - 3.6e-41 141.3 27.6 4.4e-41 141.0 27.6 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 CCU99008.1 - 1.9e-06 27.7 1.9 3.1e-06 27.0 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CCU99008.1 - 0.027 14.3 0.9 0.041 13.7 0.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCU99008.1 - 0.16 11.8 0.9 0.29 11.0 0.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CCU99008.1 - 0.35 10.8 1.8 0.58 10.0 1.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYDLN_acid PF09538.10 CCU99008.1 - 0.59 10.8 0.1 0.59 10.8 0.1 3.4 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TFIIA PF03153.13 CCU99008.1 - 1.3 8.9 14.6 1.5 8.7 14.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop53 PF07767.11 CCU99008.1 - 5.6 6.2 28.6 8.6 5.6 28.6 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) UbiA PF01040.18 CCU99009.1 - 4e-54 183.6 22.5 5.2e-54 183.2 22.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Bax1-I PF01027.20 CCU99009.1 - 1.9 8.3 10.8 1.2 8.9 0.7 2.6 3 0 0 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 adh_short PF00106.25 CCU99010.1 - 3.8e-31 108.1 0.0 1.7e-28 99.4 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CCU99010.1 - 7.1e-22 78.1 0.1 1.1e-18 67.7 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCU99010.1 - 1e-08 35.3 0.1 1.6e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 KR domain YAcAr PF10686.9 CCU99010.1 - 0.0023 17.8 1.3 0.46 10.5 0.1 4.0 3 1 2 5 5 5 1 YspA, cpYpsA-related SLOG family Epimerase PF01370.21 CCU99010.1 - 0.017 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCU99010.1 - 0.051 12.6 0.1 0.074 12.0 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DASH_Dam1 PF08653.10 CCU99012.1 - 5.7e-22 77.3 0.1 8.4e-22 76.7 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Acylphosphatase PF00708.18 CCU99013.1 - 2.3e-17 63.2 0.1 2.5e-17 63.1 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase Acyltransferase PF01553.21 CCU99014.1 - 1.1e-12 47.7 0.0 8.2e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase UvrD-helicase PF00580.21 CCU99015.1 - 6.9e-37 127.6 0.0 2.9e-36 125.6 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 CCU99015.1 - 9.9e-17 61.6 0.1 1.3e-16 61.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCU99015.1 - 0.00051 19.8 0.1 0.00083 19.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CCU99015.1 - 0.0018 18.1 0.0 0.0025 17.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCU99015.1 - 0.039 14.2 0.0 0.071 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Terminase_6 PF03237.15 CCU99015.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 1 0 1 1 1 0 Terminase-like family UvrD_C PF13361.6 CCU99016.1 - 3.5e-64 217.4 0.0 1.1e-63 215.7 0.0 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 CCU99016.1 - 3.3e-13 49.3 0.6 2e-12 46.8 0.6 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CCU99016.1 - 0.00036 20.4 0.0 0.00083 19.2 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 CCU99016.1 - 0.034 13.8 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mago-bind PF09282.10 CCU99016.1 - 0.035 14.0 0.2 0.076 12.9 0.2 1.6 1 0 0 1 1 1 0 Mago binding Mito_carr PF00153.27 CCU99017.1 - 5.6e-51 170.4 9.4 1.2e-16 60.4 0.3 4.1 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CCU99017.1 - 0.024 13.8 0.0 6.2 5.9 0.0 2.7 2 1 0 2 2 2 0 Gammaproteobacterial serine protease DUF812 PF05667.11 CCU99018.1 - 0.47 9.3 24.1 0.61 8.9 24.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Inv-AAD PF18785.1 CCU99019.1 - 1.3e-23 83.3 0.1 2.1e-20 72.9 0.1 2.3 2 0 0 2 2 2 2 Invertebrate-AID/APOBEC-deaminase PAP2 PF01569.21 CCU99019.1 - 2.2e-11 43.7 7.2 1.8e-10 40.7 6.6 2.2 1 1 0 1 1 1 1 PAP2 superfamily dCMP_cyt_deam_1 PF00383.23 CCU99019.1 - 6.3e-05 22.8 0.2 0.00029 20.7 0.2 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 CCU99019.1 - 0.0064 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain DUF212 PF02681.14 CCU99019.1 - 0.026 14.6 0.0 8.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Divergent PAP2 family UbiA PF01040.18 CCU99019.1 - 0.15 11.4 7.4 0.021 14.1 2.6 1.9 2 0 0 2 2 2 0 UbiA prenyltransferase family Peptidase_M20 PF01546.28 CCU99020.1 - 6.8e-35 120.6 0.0 8.8e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CCU99020.1 - 1.4e-12 47.4 0.0 2.2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Sde2_N_Ubi PF13019.6 CCU99023.1 - 2.2e-25 89.4 6.1 2.2e-25 89.4 6.1 2.0 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Cytochrom_B562 PF07361.11 CCU99023.1 - 0.13 12.9 0.4 0.13 12.9 0.4 1.9 2 0 0 2 2 2 0 Cytochrome b562 Amidase PF01425.21 CCU99024.1 - 1.5e-63 215.3 1.2 4.1e-44 151.3 0.0 2.2 1 1 1 2 2 2 2 Amidase Mito_carr PF00153.27 CCU99025.1 - 1.2e-56 188.7 8.9 2.6e-19 68.9 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CCU99025.1 - 0.0014 17.9 3.6 0.032 13.4 3.6 3.0 1 1 0 1 1 1 1 Gammaproteobacterial serine protease DUF2835 PF11197.8 CCU99025.1 - 0.11 12.3 0.2 4.4 7.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2835) YtxH PF12732.7 CCU99025.1 - 0.23 12.0 2.4 10 6.7 0.4 2.5 2 0 0 2 2 2 0 YtxH-like protein Nop52 PF05997.12 CCU99026.1 - 1.8e-46 158.7 0.0 3.2e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF717 PF05338.12 CCU99026.1 - 0.097 12.8 0.3 12 6.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF717) Dabb PF07876.12 CCU99027.1 - 2.4e-09 37.7 0.1 4.9e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Caskin-Pro-rich PF16907.5 CCU99027.1 - 0.24 11.9 1.6 0.6 10.7 0.2 2.2 2 0 0 2 2 2 0 Proline rich region of Caskin proteins PIG-S PF10510.9 CCU99028.1 - 2.8e-87 293.7 0.4 6.2e-75 253.0 0.0 2.1 1 1 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Pex24p PF06398.11 CCU99029.1 - 1.4e-30 106.5 4.2 1.9e-30 106.1 4.2 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin ATP12 PF07542.11 CCU99030.1 - 1.7e-43 147.8 0.2 3.1e-43 146.9 0.2 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein TPR_2 PF07719.17 CCU99031.1 - 6.7e-07 29.0 7.3 0.00016 21.5 0.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CCU99031.1 - 5.5e-06 26.0 1.2 0.0031 17.3 0.1 2.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CCU99031.1 - 0.0019 18.8 4.9 0.44 11.2 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCU99031.1 - 0.015 16.1 0.2 0.015 16.1 0.2 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ntox27 PF15531.6 CCU99031.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 27 TPR_8 PF13181.6 CCU99031.1 - 0.41 11.0 0.0 0.41 11.0 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CCU99031.1 - 5.3 6.8 8.3 2.2 8.0 0.2 2.6 3 0 0 3 3 3 0 TPR repeat NADH-u_ox-rdase PF10785.9 CCU99032.1 - 7.9e-32 109.8 0.3 1.1e-31 109.3 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit RsfS PF02410.15 CCU99033.1 - 1.6e-09 38.1 0.1 5.1e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation Neugrin PF06413.11 CCU99033.1 - 3e-08 34.0 0.1 4.5e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 CCU99033.1 - 1.5e-06 28.5 0.5 2.7e-06 27.6 0.5 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF2894 PF11445.8 CCU99033.1 - 0.0042 17.6 0.6 0.0074 16.8 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2894) MarR_2 PF12802.7 CCU99033.1 - 0.07 13.0 0.2 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 MarR family SYS1 PF09801.9 CCU99034.1 - 7.1e-19 68.4 7.4 7.5e-17 61.8 5.8 2.2 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network Mannosyl_trans2 PF04188.13 CCU99035.1 - 5.7e-32 111.6 0.2 7.5e-32 111.2 0.2 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) PMT_2 PF13231.6 CCU99035.1 - 0.0024 18.1 6.2 0.0024 18.1 6.2 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase GSAP-16 PF14959.6 CCU99035.1 - 0.078 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term PMT PF02366.18 CCU99035.1 - 0.3 10.6 7.6 0.66 9.5 7.6 1.6 1 1 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase SRP54 PF00448.22 CCU99036.1 - 1e-74 250.4 0.1 1.9e-74 249.6 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CCU99036.1 - 1.4e-31 109.0 13.8 2.4e-31 108.3 1.1 3.7 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 CCU99036.1 - 6.4e-16 58.3 0.7 1.7e-15 57.0 0.7 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.6 CCU99036.1 - 7.5e-05 23.0 0.2 0.00035 20.9 0.0 2.2 3 0 0 3 3 1 1 AAA domain AAA_33 PF13671.6 CCU99036.1 - 0.00015 22.0 0.1 0.00045 20.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CCU99036.1 - 0.00092 18.3 1.3 0.019 14.0 0.0 2.9 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CCU99036.1 - 0.001 18.7 0.2 0.011 15.4 0.2 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 CCU99036.1 - 0.0034 17.8 0.2 0.016 15.6 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CCU99036.1 - 0.0046 17.4 0.1 0.032 14.6 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain MobB PF03205.14 CCU99036.1 - 0.0046 16.9 0.0 0.014 15.3 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RAI16-like PF10257.9 CCU99036.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein APS_kinase PF01583.20 CCU99036.1 - 0.022 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 CCU99036.1 - 0.025 15.1 0.3 0.13 12.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 CCU99036.1 - 0.035 13.8 0.9 0.068 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_8 PF12780.7 CCU99036.1 - 0.035 13.4 0.6 5.2 6.3 0.0 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region D4 ATP_bind_1 PF03029.17 CCU99036.1 - 0.038 13.8 0.1 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 CCU99036.1 - 0.04 14.0 0.0 0.091 12.8 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CCU99036.1 - 0.049 13.6 0.2 0.41 10.5 0.0 2.2 1 1 0 2 2 2 0 AAA domain DUF3052 PF11253.8 CCU99036.1 - 0.05 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) SRPRB PF09439.10 CCU99036.1 - 0.057 12.8 4.2 3.8 6.9 0.1 3.8 3 1 0 4 4 4 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 CCU99036.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 CCU99036.1 - 0.076 12.7 1.3 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 Thymidylate kinase Peptidase_S78_2 PF14550.6 CCU99036.1 - 0.11 12.6 1.1 0.17 12.0 0.2 1.8 2 0 0 2 2 2 0 Putative phage serine protease XkdF AAA_24 PF13479.6 CCU99036.1 - 0.13 11.9 1.8 0.71 9.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain ArsA_ATPase PF02374.15 CCU99036.1 - 0.75 8.9 3.4 0.76 8.9 0.1 2.5 3 0 0 3 3 3 0 Anion-transporting ATPase XPG_I PF00867.18 CCU99037.1 - 4.8e-15 55.7 0.0 7.7e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CCU99037.1 - 0.00063 20.2 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Ribosomal_L10 PF00466.20 CCU99038.1 - 0.019 15.1 0.0 5.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L10 F-box-like PF12937.7 CCU99039.1 - 2.9e-05 23.9 6.4 9e-05 22.3 6.4 1.9 1 0 0 1 1 1 1 F-box-like E1-E2_ATPase PF00122.20 CCU99040.1 - 3.9e-47 160.1 1.2 3.9e-47 160.1 1.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CCU99040.1 - 1.4e-33 117.0 0.2 2.8e-33 116.0 0.2 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CCU99040.1 - 6.5e-05 22.8 0.5 0.011 15.5 0.7 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CCU99040.1 - 0.00044 20.7 0.1 0.00096 19.6 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DHOase PF12890.7 CCU99040.1 - 0.08 12.9 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Dihydro-orotase-like Ribosomal_L12 PF00542.19 CCU99041.1 - 7.4e-21 74.3 10.9 4.9e-20 71.6 8.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CCU99041.1 - 6.7e-15 54.5 6.5 6.7e-15 54.5 6.5 2.8 3 0 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 CCU99041.1 - 0.013 16.1 6.5 0.013 16.1 6.5 2.7 2 1 0 2 2 2 0 60s Acidic ribosomal protein DAHP_snth_FXD PF18152.1 CCU99041.1 - 0.24 11.3 1.4 2.4 8.1 0.3 2.5 3 0 0 3 3 3 0 DAHP synthase ferredoxin-like domain ERG4_ERG24 PF01222.17 CCU99042.1 - 5.6e-127 424.1 22.8 6.5e-127 423.9 22.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Sulfate_transp PF00916.20 CCU99042.1 - 0.026 13.3 1.7 0.037 12.8 1.7 1.2 1 0 0 1 1 1 0 Sulfate permease family Syja_N PF02383.18 CCU99043.1 - 7.6e-77 258.7 0.0 1.8e-76 257.5 0.0 1.6 2 0 0 2 2 2 1 SacI homology domain Proteasome PF00227.26 CCU99044.1 - 3.7e-50 170.1 0.2 4.7e-50 169.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Homoserine_dh PF00742.19 CCU99045.1 - 7.4e-47 159.5 0.0 1.2e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CCU99045.1 - 1.4e-17 64.5 0.1 2.7e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 CCU99045.1 - 0.00083 19.8 0.1 0.002 18.6 0.1 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.22 CCU99046.1 - 8.5e-76 255.5 0.0 1.8e-75 254.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Cellulose_synt PF03552.14 CCU99046.1 - 0.45 8.9 1.3 0.67 8.4 1.3 1.1 1 0 0 1 1 1 0 Cellulose synthase NUDIX PF00293.28 CCU99047.1 - 1.5e-10 41.2 0.0 2.9e-10 40.3 0.0 1.4 2 0 0 2 2 2 1 NUDIX domain DHDPS PF00701.22 CCU99047.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family NUP PF06516.11 CCU99048.1 - 7.7e-77 258.6 1.1 2.6e-73 247.0 0.1 2.1 1 1 1 2 2 2 2 Purine nucleoside permease (NUP) TetR_C_21 PF17926.1 CCU99048.1 - 0.042 14.0 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ferric_reduct PF01794.19 CCU99049.1 - 5.2e-16 58.9 13.8 5.2e-16 58.9 13.8 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CCU99049.1 - 7.7e-15 54.9 0.1 5.6e-14 52.1 0.1 2.3 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 CCU99049.1 - 8.7e-14 51.9 0.0 3.4e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 CCU99049.1 - 0.032 14.9 0.0 0.067 13.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 CCU99049.1 - 0.068 13.7 17.4 0.95 10.1 3.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) DEAD PF00270.29 CCU99050.1 - 6.1e-33 114.1 0.2 9.1e-33 113.5 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU99050.1 - 5.6e-31 107.2 0.0 1.4e-30 105.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU99050.1 - 0.00022 21.2 0.0 0.00063 19.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCU99050.1 - 0.012 15.4 0.3 0.023 14.4 0.3 1.4 1 0 0 1 1 1 0 AAA domain DHHA2 PF02833.14 CCU99051.1 - 3.3e-30 105.2 0.0 4.6e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 CCU99051.1 - 3e-12 46.6 0.2 5e-12 46.0 0.2 1.3 1 0 0 1 1 1 1 DHH family TPR_2 PF07719.17 CCU99052.1 - 8.9e-19 66.0 8.0 8.2e-05 22.4 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 CCU99052.1 - 9.5e-19 66.4 0.6 2.3e-06 27.2 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CCU99052.1 - 4.2e-14 51.5 1.8 0.034 14.4 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 CCU99052.1 - 2.1e-12 46.5 0.7 0.00022 20.8 0.0 4.3 2 1 2 4 4 4 3 TPR repeat TPR_14 PF13428.6 CCU99052.1 - 5.6e-10 39.2 19.3 0.00045 20.8 0.1 6.9 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 CCU99052.1 - 1.9e-09 37.7 12.6 0.18 12.1 2.2 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 CCU99052.1 - 1.4e-08 35.2 24.4 4.2e-07 30.5 0.8 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 CCU99052.1 - 3.2e-07 30.8 16.9 0.016 15.7 0.7 5.5 3 1 4 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 CCU99052.1 - 4e-07 30.0 0.9 0.038 14.4 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 CCU99052.1 - 2.9e-06 27.5 9.5 0.0058 16.9 0.2 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCU99052.1 - 0.00092 19.4 4.7 0.56 10.5 0.3 2.8 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CCU99052.1 - 0.0012 19.3 5.7 13 6.7 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 CCU99052.1 - 0.0027 17.8 9.6 0.011 15.9 0.6 3.5 3 1 0 3 3 2 2 Tetratricopeptide repeat RPN7 PF10602.9 CCU99052.1 - 0.0081 15.9 0.2 0.062 13.0 0.0 2.4 2 1 1 3 3 3 1 26S proteasome subunit RPN7 TPR_7 PF13176.6 CCU99052.1 - 0.0098 15.9 7.8 7.9 6.8 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.14 CCU99052.1 - 0.032 13.7 0.2 5 6.4 0.0 2.5 2 0 0 2 2 2 0 Coatomer epsilon subunit Mit_ribos_Mrp51 PF11709.8 CCU99052.1 - 0.14 11.7 0.2 0.28 10.7 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit TPR_10 PF13374.6 CCU99052.1 - 1.3 9.0 8.7 9.8 6.2 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 CCU99053.1 - 2.6e-41 141.5 0.0 4.4e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 CCU99053.1 - 7.7e-05 22.2 0.2 0.00051 19.5 0.0 2.3 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.15 CCU99053.1 - 0.0018 18.4 0.1 0.055 13.6 0.0 2.7 2 0 0 2 2 2 1 U-box domain Vps39_2 PF10367.9 CCU99054.1 - 1.4e-05 25.4 0.0 3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 CCU99054.1 - 0.0038 17.5 0.0 0.0089 16.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 CCU99054.1 - 0.08 13.1 2.7 5.4 7.4 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCU99054.1 - 0.15 12.1 0.8 18 5.6 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PolyA_pol PF01743.20 CCU99055.1 - 8.8e-22 77.9 0.0 1.6e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CCU99055.1 - 8.3e-07 28.7 0.0 2.4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Pkinase PF00069.25 CCU99056.1 - 3.5e-63 213.5 0.0 4.2e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99056.1 - 1.5e-31 109.6 0.0 3.2e-31 108.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU99056.1 - 1.8e-05 24.2 0.0 0.00015 21.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CCU99056.1 - 0.001 18.5 0.1 0.0015 18.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCU99056.1 - 0.0033 17.4 1.7 0.26 11.2 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 CCU99056.1 - 0.042 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CCU99056.1 - 0.22 10.4 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain UAA PF08449.11 CCU99057.1 - 7.3e-38 130.5 16.9 4.1e-37 128.0 16.9 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 CCU99057.1 - 1.8e-06 28.2 22.3 3.8e-05 23.9 8.8 3.1 2 1 1 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 CCU99057.1 - 0.00064 18.8 11.8 0.055 12.4 4.9 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 CCU99057.1 - 0.012 15.0 11.8 0.094 12.1 3.8 2.7 2 1 0 2 2 2 0 Triose-phosphate Transporter family Borrelia_P13 PF05628.12 CCU99057.1 - 0.054 13.4 1.7 0.13 12.2 1.1 1.9 2 0 0 2 2 2 0 Borrelia membrane protein P13 Nuc_sug_transp PF04142.15 CCU99057.1 - 0.057 12.6 14.0 0.095 11.9 1.1 2.3 2 1 0 2 2 2 0 Nucleotide-sugar transporter DAP3 PF10236.9 CCU99058.1 - 1.1e-48 166.0 0.0 1.3e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CCU99058.1 - 3.2e-09 37.4 1.7 5.8e-09 36.6 1.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 CCU99058.1 - 0.0062 16.3 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 CCU99058.1 - 0.016 14.8 0.0 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CCU99058.1 - 0.029 14.4 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 CCU99058.1 - 0.072 13.0 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 CCU99058.1 - 0.091 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCU99058.1 - 0.093 13.0 0.1 0.48 10.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CCU99058.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CCU99058.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CCU99058.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mob1_phocein PF03637.17 CCU99059.1 - 3.1e-56 190.0 2.0 3.7e-56 189.8 2.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family FHA PF00498.26 CCU99060.1 - 0.00011 22.5 0.0 0.00021 21.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain GTP_EFTU PF00009.27 CCU99061.1 - 8.6e-46 155.9 0.0 1.6e-45 155.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CCU99061.1 - 8.8e-21 73.8 0.0 2e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CCU99061.1 - 3.9e-16 58.9 0.2 1.9e-07 31.0 0.0 2.5 1 1 1 2 2 2 2 Elongation factor G C-terminus RRM_1 PF00076.22 CCU99061.1 - 7.8e-12 44.8 0.0 4.3e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU_D2 PF03144.25 CCU99061.1 - 1.2e-11 44.8 0.0 3.2e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 CCU99061.1 - 7.5e-06 25.7 0.1 2.9e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV RF3_C PF16658.5 CCU99061.1 - 0.0013 18.5 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CCU99061.1 - 0.01 15.9 0.0 0.054 13.6 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF866 PF05907.13 CCU99062.1 - 1.3e-42 145.3 0.0 1.5e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Paired_CXXCH_1 PF09699.10 CCU99062.1 - 0.097 12.4 1.7 0.18 11.6 1.7 1.5 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) MCM_OB PF17207.3 CCU99062.1 - 0.13 12.1 0.3 1.4 8.7 0.0 2.3 1 1 1 2 2 2 0 MCM OB domain CDP-OH_P_transf PF01066.21 CCU99063.1 - 1e-13 51.8 0.3 1e-13 51.8 0.3 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4328 PF14219.6 CCU99063.1 - 0.027 14.0 0.3 0.053 13.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Metallophos PF00149.28 CCU99064.1 - 1e-13 52.3 0.0 1.9e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GAT PF03127.14 CCU99064.1 - 0.0032 17.7 0.2 0.009 16.3 0.2 1.7 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 CCU99064.1 - 0.18 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 VHS domain Nop53 PF07767.11 CCU99065.1 - 2.3e-92 310.4 34.8 3.2e-92 310.0 34.8 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) FAD-oxidase_C PF02913.19 CCU99065.1 - 4.4e-28 98.6 0.0 4.4e-28 98.6 0.0 2.0 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CCU99065.1 - 9e-25 87.0 1.8 9e-25 87.0 1.8 2.2 2 0 0 2 2 2 1 FAD binding domain HIG_1_N PF04588.13 CCU99065.1 - 0.00042 20.5 0.3 0.0011 19.2 0.3 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region OST3_OST6 PF04756.13 CCU99066.1 - 9.2e-47 159.8 6.7 2.2e-29 102.8 5.9 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Wzy_C PF04932.15 CCU99066.1 - 0.57 9.8 11.2 5.8 6.5 4.6 3.0 3 0 0 3 3 3 0 O-Antigen ligase Ribosomal_L16 PF00252.18 CCU99067.1 - 1.3e-36 125.5 0.1 1.7e-36 125.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Pribosyltran PF00156.27 CCU99068.1 - 2.6e-12 46.5 0.3 3.8e-12 46.0 0.3 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 CCU99068.1 - 0.026 14.1 0.1 0.04 13.4 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase WD40 PF00400.32 CCU99069.1 - 6.4e-46 153.4 16.5 7.7e-06 26.6 0.3 8.1 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU99069.1 - 2.5e-12 46.9 0.2 0.78 10.1 0.0 6.4 2 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCU99069.1 - 0.018 14.0 0.1 2 7.3 0.0 3.3 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CCU99069.1 - 0.13 11.6 0.0 13 5.0 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain Axin_b-cat_bind PF08833.10 CCU99069.1 - 0.87 9.7 2.6 0.94 9.6 0.0 2.4 3 0 0 3 3 3 0 Axin beta-catenin binding domain Nup160 PF11715.8 CCU99069.1 - 1.9 7.0 4.7 21 3.6 0.1 3.6 3 1 0 4 4 4 0 Nucleoporin Nup120/160 Cid2 PF09774.9 CCU99071.1 - 8.9e-27 94.5 2.5 1.3e-26 94.0 2.5 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 TRI9 PF08195.11 CCU99071.1 - 0.094 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 TRI9 protein NAD_Gly3P_dh_C PF07479.14 CCU99072.1 - 1.5e-47 161.5 0.1 3.2e-47 160.4 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 CCU99072.1 - 6.7e-34 117.1 0.1 1e-33 116.5 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4663 PF15668.5 CCU99072.1 - 0.21 10.6 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) EI24 PF07264.11 CCU99074.1 - 2.9e-18 66.7 8.8 5e-18 66.0 8.8 1.4 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Glyco_hydro_3_C PF01915.22 CCU99075.1 - 1.5e-55 188.3 0.0 2.7e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CCU99075.1 - 1.5e-42 146.1 0.0 2.4e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CCU99075.1 - 2.4e-20 72.4 0.2 4.7e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain NUDIX PF00293.28 CCU99076.1 - 2.5e-09 37.3 0.0 4.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DEAD PF00270.29 CCU99077.1 - 3.6e-43 147.4 0.0 6.2e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU99077.1 - 5.1e-22 78.3 0.0 2.3e-21 76.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU99077.1 - 2.2e-05 24.5 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Thiamine_BP PF01910.17 CCU99078.1 - 9.1e-15 54.3 0.0 3.2e-14 52.6 0.0 1.7 1 1 0 1 1 1 1 Thiamine-binding protein Aminotran_3 PF00202.21 CCU99079.1 - 3.9e-97 325.5 0.0 5.7e-97 324.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ASL_C2 PF14698.6 CCU99079.1 - 0.029 15.1 0.3 13 6.6 0.0 2.8 2 0 0 2 2 2 0 Argininosuccinate lyase C-terminal Mob1_phocein PF03637.17 CCU99080.1 - 5.7e-69 231.5 0.1 6.5e-69 231.3 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family His_Phos_2 PF00328.22 CCU99081.1 - 1e-44 153.5 0.0 1.7e-44 152.7 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DctQ PF04290.12 CCU99081.1 - 0.18 11.7 0.3 3.1 7.7 0.1 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component GATase_6 PF13522.6 CCU99082.1 - 2.2e-14 53.8 0.1 4.5e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CCU99082.1 - 3.5e-10 39.9 0.0 1.1e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 CCU99082.1 - 1.8e-09 37.3 0.0 3.1e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 CCU99082.1 - 0.00013 20.9 0.0 0.0013 17.7 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Catalase_C PF18011.1 CCU99082.1 - 0.14 11.8 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain found in long catalases Mito_carr PF00153.27 CCU99083.1 - 7e-57 189.4 3.0 1.7e-18 66.3 0.7 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Y_phosphatase2 PF03162.13 CCU99084.1 - 7e-49 165.6 0.0 1e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Aldo_ket_red PF00248.21 CCU99084.1 - 2.3e-14 53.3 0.0 3.8e-08 32.9 0.0 3.1 3 0 0 3 3 3 3 Aldo/keto reductase family Y_phosphatase3 PF13350.6 CCU99084.1 - 0.00088 19.3 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Tegument_dsDNA PF12818.7 CCU99084.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 dsDNA viral tegument protein Chitin_synth_1 PF01644.17 CCU99085.1 - 6.1e-69 231.1 0.0 9.2e-69 230.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CCU99085.1 - 4.5e-26 90.6 0.0 2.3e-25 88.3 0.0 2.1 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CCU99085.1 - 2.8e-24 85.7 7.0 2.8e-20 72.5 0.1 2.7 3 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CCU99085.1 - 0.00085 19.3 12.5 0.00085 19.3 12.5 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DASH_Ask1 PF08655.10 CCU99086.1 - 6.5e-28 96.4 0.3 1.1e-27 95.7 0.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 OTU PF02338.19 CCU99087.1 - 1.2e-24 87.2 0.0 2.2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CCU99087.1 - 0.0082 15.6 0.0 0.093 12.2 0.0 2.1 1 1 0 1 1 1 1 Peptidase C65 Otubain Actin PF00022.19 CCU99088.1 - 1.6e-116 389.3 0.0 2.2e-116 388.9 0.0 1.2 1 0 0 1 1 1 1 Actin TubC_N PF18563.1 CCU99088.1 - 0.19 11.7 0.0 0.68 10.0 0.0 1.8 2 0 0 2 2 2 0 TubC N-terminal docking domain Phosphoesterase PF04185.14 CCU99089.1 - 1.5e-71 241.5 3.9 2.5e-71 240.8 3.9 1.3 1 0 0 1 1 1 1 Phosphoesterase family MFS_1 PF07690.16 CCU99090.1 - 1.8e-20 73.2 31.5 1.3e-18 67.1 27.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.18 CCU99091.1 - 7.1e-14 51.9 6.0 9.9e-14 51.4 6.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 CCU99091.1 - 0.0085 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AAA_11 PF13086.6 CCU99092.1 - 1.5e-44 152.7 0.6 2.2e-44 152.2 0.6 1.2 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 CCU99092.1 - 1.6e-44 151.9 0.0 2.3e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCU99092.1 - 3.7e-15 56.5 2.7 2.2e-14 54.0 1.4 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCU99092.1 - 3.6e-13 49.7 3.8 6.7e-11 42.3 3.8 2.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCU99092.1 - 0.00055 20.4 1.2 0.0035 17.7 1.2 2.4 1 0 0 1 1 1 1 AAA ATPase domain UvrD-helicase PF00580.21 CCU99092.1 - 0.00081 19.0 0.4 0.0015 18.2 0.1 1.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 CCU99092.1 - 0.0062 16.3 0.2 3.8 7.2 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CCU99092.1 - 0.03 14.3 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 CCU99092.1 - 0.03 13.8 0.0 0.072 12.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 CCU99092.1 - 0.043 14.1 0.1 0.15 12.3 0.0 2.0 2 1 0 2 2 1 0 AAA domain PIF1 PF05970.14 CCU99092.1 - 0.083 12.0 0.1 6.1 5.9 0.0 2.4 3 0 0 3 3 3 0 PIF1-like helicase DUF2075 PF09848.9 CCU99092.1 - 0.21 10.8 0.2 0.43 9.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IATP PF04568.12 CCU99093.1 - 5.3e-12 46.0 0.3 5.8e-12 45.9 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP S8_pro-domain PF16470.5 CCU99093.1 - 0.003 18.3 0.0 0.004 17.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase S8 pro-domain Cytochrom_C_2 PF01322.20 CCU99093.1 - 0.035 15.0 0.0 0.041 14.8 0.0 1.0 1 0 0 1 1 1 0 Cytochrome C' DUF2639 PF11121.8 CCU99093.1 - 0.22 11.6 1.9 0.64 10.1 1.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2639) ATP_sub_h PF10775.9 CCU99094.1 - 9e-20 70.4 1.4 9e-20 70.4 1.4 2.1 2 1 0 2 2 2 1 ATP synthase complex subunit h Got1 PF04178.12 CCU99095.1 - 2.8e-09 37.4 0.4 3.2e-09 37.2 0.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Phage_holin_5_1 PF06946.11 CCU99095.1 - 0.1 13.0 0.1 0.12 12.7 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 eIF2_C PF09173.11 CCU99096.1 - 1.4e-36 124.6 0.2 3.3e-36 123.4 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CCU99096.1 - 4.2e-20 72.1 0.4 2.9e-19 69.4 0.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CCU99096.1 - 1.4e-12 47.8 0.6 1.4e-12 47.8 0.6 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 CCU99096.1 - 0.0012 18.8 0.4 0.0096 15.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CCU99096.1 - 0.013 15.6 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CCU99096.1 - 0.015 15.3 0.8 0.07 13.1 0.1 2.3 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain YdjO PF14169.6 CCU99096.1 - 0.043 13.5 0.2 0.088 12.5 0.2 1.4 1 0 0 1 1 1 0 Cold-inducible protein YdjO Dynamin_N PF00350.23 CCU99096.1 - 0.11 12.5 0.1 0.37 10.8 0.1 2.0 1 1 0 1 1 1 0 Dynamin family PPR_2 PF13041.6 CCU99097.1 - 7.6e-10 38.8 0.0 0.00014 22.0 0.0 3.3 3 0 0 3 3 3 2 PPR repeat family ERAP1_C PF11838.8 CCU99097.1 - 0.0023 17.6 1.0 0.0072 15.9 1.0 1.9 1 0 0 1 1 1 1 ERAP1-like C-terminal domain PPR PF01535.20 CCU99097.1 - 0.019 15.2 0.0 2.7 8.4 0.0 3.2 4 0 0 4 4 4 0 PPR repeat TPR_19 PF14559.6 CCU99097.1 - 0.33 11.5 4.2 1 9.9 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat CRC_subunit PF08624.10 CCU99098.1 - 3.1e-48 163.6 0.2 1.1e-47 161.9 0.1 1.9 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Evr1_Alr PF04777.13 CCU99100.1 - 1.7e-25 89.4 0.6 2.5e-25 88.8 0.1 1.6 2 0 0 2 2 2 1 Erv1 / Alr family COX16 PF14138.6 CCU99100.1 - 6.3e-14 52.3 1.3 9.7e-14 51.6 1.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 SET PF00856.28 CCU99101.1 - 1.1e-10 42.2 0.0 4.6e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 SET domain NST1 PF13945.6 CCU99102.1 - 1.5e-20 74.1 0.1 1.5e-20 74.1 0.1 4.5 3 1 1 4 4 4 2 Salt tolerance down-regulator HC2 PF07382.11 CCU99102.1 - 0.0036 17.4 36.2 0.0036 17.4 36.2 2.1 2 1 0 2 2 2 1 Histone H1-like nucleoprotein HC2 YL1 PF05764.13 CCU99102.1 - 0.034 14.3 0.1 0.034 14.3 0.1 3.9 2 1 1 3 3 3 0 YL1 nuclear protein zf-C2H2_2 PF12756.7 CCU99104.1 - 2.7e-36 123.9 12.9 1.8e-29 102.0 0.7 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CCU99104.1 - 1.3e-09 38.1 9.4 2.9e-06 27.4 2.9 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCU99104.1 - 3.4e-07 30.4 3.5 3.4e-07 30.4 3.5 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CCU99104.1 - 0.0093 16.7 1.1 0.0093 16.7 1.1 5.3 5 1 0 5 5 5 1 C2H2-type zinc finger DUF4606 PF15379.6 CCU99104.1 - 0.014 15.7 0.4 0.047 13.9 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) zf-C2H2 PF00096.26 CCU99104.1 - 0.014 15.9 3.1 0.014 15.9 3.1 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CCU99104.1 - 0.014 15.4 2.0 0.014 15.4 2.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-DBF PF07535.12 CCU99104.1 - 0.053 13.6 1.0 0.053 13.6 1.0 3.5 4 0 0 4 4 4 0 DBF zinc finger DUF629 PF04780.12 CCU99104.1 - 0.054 12.0 6.8 3.7 6.0 1.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF629) MRP-L28 PF09812.9 CCU99104.1 - 0.3 11.2 4.4 0.16 12.1 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 NAM-associated PF14303.6 CCU99104.1 - 2.1 9.0 9.3 0.068 13.9 2.6 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain zf-LYAR PF08790.11 CCU99104.1 - 2.2 8.3 5.9 3.7 7.5 0.4 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.6 CCU99104.1 - 2.5 8.7 7.9 44 4.7 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger double domain Vps39_2 PF10367.9 CCU99104.1 - 3.1 8.3 7.2 2.1 8.8 0.2 2.9 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 HNH_5 PF14279.6 CCU99104.1 - 7.4 6.5 9.9 2.3 8.1 0.2 3.6 4 0 0 4 4 4 0 HNH endonuclease Nup35_RRM_2 PF14605.6 CCU99105.1 - 3.1e-08 33.5 0.0 0.0026 17.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 CCU99105.1 - 5.8e-08 32.4 0.0 0.0045 16.8 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 CCU99105.1 - 2.2e-07 31.1 0.1 5.7e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 CCU99105.1 - 0.00023 21.0 0.2 0.0005 19.9 0.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCU99105.1 - 0.011 15.8 0.2 0.026 14.6 0.2 1.7 1 0 0 1 1 1 0 Zinc finger domain Ribosomal_L18A PF01775.17 CCU99106.1 - 9.2e-53 177.5 1.3 1.1e-52 177.2 1.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Vps35 PF03635.17 CCU99107.1 - 3.1e-295 981.4 0.1 3.8e-295 981.2 0.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF2357 PF09823.9 CCU99107.1 - 0.087 12.1 0.6 0.23 10.7 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) TIP120 PF08623.10 CCU99107.1 - 0.09 12.5 0.8 0.33 10.7 0.4 2.1 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) HisKA_3 PF07730.13 CCU99107.1 - 1 9.9 5.6 1.6 9.3 1.9 3.4 4 0 0 4 4 4 0 Histidine kinase PhoLip_ATPase_N PF16209.5 CCU99108.1 - 5.2e-19 67.7 2.4 1.3e-18 66.5 2.4 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CCU99108.1 - 3.1e-13 49.6 0.0 1.6e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CCU99108.1 - 4.7e-13 49.0 0.0 3.2e-11 43.2 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCU99108.1 - 7.7e-09 36.1 0.6 4.1e-08 33.8 0.6 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Afaf PF15339.6 CCU99108.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Acrosome formation-associated factor DUF1772 PF08592.11 CCU99108.1 - 0.074 13.4 0.1 0.32 11.3 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) RRM_1 PF00076.22 CCU99109.1 - 6.3e-13 48.3 0.0 1.4e-12 47.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) THF_DHG_CYH PF00763.23 CCU99110.1 - 3.3e-27 95.1 0.0 5.5e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 CCU99110.1 - 3.5e-13 49.2 0.0 1e-07 31.4 0.0 2.9 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.22 CCU99110.1 - 0.037 13.0 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Syntaxin_2 PF14523.6 CCU99111.1 - 1.3e-17 64.0 2.2 1.3e-17 64.0 2.2 3.1 3 0 0 3 3 3 1 Syntaxin-like protein TAF6_C PF07571.13 CCU99111.1 - 3.9e-17 62.4 0.0 8.8e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 CCU99111.1 - 1.5e-14 53.9 0.0 4.5e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) SNARE PF05739.19 CCU99111.1 - 3.9e-06 26.8 0.1 1.1e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CCU99111.1 - 4e-06 26.6 12.5 6.7e-06 25.9 12.5 1.3 1 0 0 1 1 1 1 Syntaxin Spectrin PF00435.21 CCU99111.1 - 0.48 10.9 7.2 9.6 6.8 3.6 2.5 2 0 0 2 2 2 0 Spectrin repeat KASH_CCD PF14662.6 CCU99111.1 - 0.53 10.1 12.8 3 7.6 0.3 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 CCU99111.1 - 1.6 8.7 6.6 0.98 9.5 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DnaJ_C PF01556.18 CCU99113.1 - 1.8e-31 109.3 0.0 2.5e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCU99113.1 - 1.1e-24 86.2 0.5 1.9e-24 85.5 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCU99113.1 - 1.2e-12 48.0 23.1 2.2e-12 47.2 23.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CCU99113.1 - 0.17 11.9 16.6 0.24 11.4 4.2 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF1356 PF07092.12 CCU99113.1 - 1.1 8.5 3.8 2.2 7.5 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Cytochrom_c3_2 PF14537.6 CCU99113.1 - 1.9 9.0 12.6 5.3 7.6 10.6 2.3 1 1 1 2 2 2 0 Cytochrome c3 GF_recep_IV PF14843.6 CCU99113.1 - 2.1 8.1 13.2 4.6 7.0 13.1 1.5 1 1 0 1 1 1 0 Growth factor receptor domain IV Lyase_1 PF00206.20 CCU99114.1 - 1e-97 327.3 0.0 1.3e-97 326.9 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 CCU99114.1 - 3.8e-26 91.6 0.0 8.3e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Calreticulin PF00262.18 CCU99115.1 - 6.3e-160 532.0 9.4 8e-160 531.7 9.4 1.1 1 0 0 1 1 1 1 Calreticulin family Peptidase_S8 PF00082.22 CCU99116.1 - 1.6e-39 136.0 1.4 2.3e-39 135.5 1.4 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CCU99116.1 - 8.4e-22 77.0 0.2 1.7e-21 76.0 0.2 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF3592 PF12158.8 CCU99116.1 - 0.03 14.4 0.1 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) LuxS PF02664.15 CCU99116.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) DUF2970 PF11174.8 CCU99116.1 - 0.13 12.1 0.6 0.28 11.1 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) S8_pro-domain PF16470.5 CCU99116.1 - 0.25 12.1 0.0 0.25 12.1 0.0 2.5 2 0 0 2 2 2 0 Peptidase S8 pro-domain DUF2407_C PF13373.6 CCU99117.1 - 2.6e-10 40.6 2.8 2.6e-10 40.6 2.8 3.1 2 1 1 3 3 3 1 DUF2407 C-terminal domain DUF2407 PF10302.9 CCU99117.1 - 0.00016 22.2 0.3 0.00095 19.7 0.0 2.3 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain RNR_inhib PF08591.10 CCU99117.1 - 0.13 13.5 0.3 0.32 12.3 0.3 1.6 1 0 0 1 1 1 0 Ribonucleotide reductase inhibitor SNF2_N PF00176.23 CCU99118.1 - 4.5e-72 242.7 0.1 9.7e-72 241.6 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CCU99118.1 - 3.2e-36 123.8 0.1 3.2e-36 123.8 0.1 2.8 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 CCU99118.1 - 3.2e-31 108.4 5.9 3.2e-31 108.4 5.9 3.6 3 0 0 3 3 2 1 HAND Helicase_C PF00271.31 CCU99118.1 - 3.3e-21 75.7 0.0 1.9e-18 66.8 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU99118.1 - 2.8e-08 34.0 0.0 1.5e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CCU99118.1 - 4e-08 32.8 0.1 9.4e-08 31.6 0.1 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CCU99118.1 - 1e-06 28.6 0.0 2.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 CCU99118.1 - 5.8e-05 23.2 0.0 0.0017 18.5 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain DBINO PF13892.6 CCU99118.1 - 8.8e-05 22.9 0.9 8.8e-05 22.9 0.9 3.9 6 0 0 6 6 5 1 DNA-binding domain ERCC3_RAD25_C PF16203.5 CCU99118.1 - 0.00099 18.4 1.3 0.036 13.3 0.2 2.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_14 PF13173.6 CCU99118.1 - 0.0029 17.6 0.2 0.015 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain HEAT PF02985.22 CCU99119.1 - 1.5e-18 65.3 9.8 0.00038 20.5 0.0 9.8 11 0 0 11 11 10 3 HEAT repeat HEAT_EZ PF13513.6 CCU99119.1 - 6.6e-16 58.4 15.7 1.2e-09 38.4 0.0 8.1 8 1 1 9 9 9 4 HEAT-like repeat IBN_N PF03810.19 CCU99119.1 - 1.4e-09 37.7 1.5 1.2e-07 31.5 0.0 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CCU99119.1 - 2.5e-06 27.8 19.2 0.01 16.2 0.0 6.3 3 2 2 6 6 6 3 HEAT repeats Cnd1 PF12717.7 CCU99119.1 - 0.0012 18.9 0.1 0.0035 17.4 0.1 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 MukF_M PF17192.4 CCU99119.1 - 0.0056 16.4 0.2 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 MukF middle domain ParcG PF10274.9 CCU99119.1 - 0.02 15.0 0.0 0.1 12.7 0.0 2.2 1 0 0 1 1 1 0 Parkin co-regulated protein TIP120 PF08623.10 CCU99119.1 - 0.025 14.4 0.2 0.31 10.8 0.0 2.8 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) Arm PF00514.23 CCU99119.1 - 0.052 13.6 9.7 1.9 8.6 0.1 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat NUC173 PF08161.12 CCU99119.1 - 0.065 12.9 1.1 24 4.5 0.1 3.9 4 0 0 4 4 4 0 NUC173 domain Vac14_Fab1_bd PF12755.7 CCU99119.1 - 0.086 13.4 2.0 20 5.9 0.0 4.8 3 2 3 6 6 6 0 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 CCU99119.1 - 0.28 10.2 3.1 16 4.4 0.0 3.7 2 2 0 3 3 3 0 RNAPII transcription regulator C-terminal DAHP_synth_1 PF00793.20 CCU99120.1 - 4.5e-98 327.5 0.0 5.5e-98 327.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COG7 PF10191.9 CCU99121.1 - 1.5e-30 106.1 0.0 6.7e-24 84.2 0.0 2.1 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) Ldh_1_N PF00056.23 CCU99122.1 - 1.1e-43 148.7 0.1 1.7e-43 148.1 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CCU99122.1 - 1.8e-41 141.9 0.5 7.3e-41 139.9 0.1 2.1 3 0 0 3 3 3 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CCU99122.1 - 3.7e-05 22.9 0.0 5.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CCU99122.1 - 0.057 13.3 0.2 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 CCU99122.1 - 0.13 12.7 0.5 1.6 9.1 0.0 2.7 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain AAA PF00004.29 CCU99123.1 - 1.3e-58 197.1 0.0 7.8e-44 149.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCU99123.1 - 9.6e-11 42.4 2.4 0.0042 17.5 0.5 4.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CCU99123.1 - 2.9e-05 24.1 0.3 0.0093 16.0 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CCU99123.1 - 0.00032 20.5 0.0 0.0032 17.2 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCU99123.1 - 0.00055 20.2 0.2 0.043 14.1 0.1 3.1 2 1 1 3 3 3 1 AAA domain DUF815 PF05673.13 CCU99123.1 - 0.00074 18.7 0.2 0.82 8.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) TsaE PF02367.17 CCU99123.1 - 0.00091 19.2 0.1 0.3 11.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CCU99123.1 - 0.00097 19.7 0.0 0.11 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CCU99123.1 - 0.0013 18.3 0.9 0.025 14.2 0.1 2.9 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CCU99123.1 - 0.0017 18.1 0.1 0.0071 16.1 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 CCU99123.1 - 0.0022 18.1 0.0 0.28 11.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CCU99123.1 - 0.003 16.9 0.1 0.0071 15.7 0.0 1.5 2 0 0 2 2 1 1 KaiC Parvo_NS1 PF01057.17 CCU99123.1 - 0.0049 16.0 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NACHT PF05729.12 CCU99123.1 - 0.0053 16.7 1.1 1.2 9.0 0.0 3.0 4 0 0 4 4 3 1 NACHT domain AAA_2 PF07724.14 CCU99123.1 - 0.0053 16.9 0.0 0.014 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CCU99123.1 - 0.0073 15.7 0.5 0.041 13.3 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CCU99123.1 - 0.0096 15.5 0.0 0.058 12.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 CCU99123.1 - 0.01 15.6 0.0 0.67 9.6 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 CCU99123.1 - 0.015 15.6 0.0 0.27 11.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 CCU99123.1 - 0.025 13.8 0.1 0.087 12.0 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain RNA_helicase PF00910.22 CCU99123.1 - 0.043 14.2 0.0 0.11 12.9 0.0 1.7 2 0 0 2 2 1 0 RNA helicase PhoH PF02562.16 CCU99123.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 CCU99123.1 - 0.053 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCU99123.1 - 0.063 13.0 0.2 12 5.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Vps4_C PF09336.10 CCU99123.1 - 0.085 12.9 0.0 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain T2SSE PF00437.20 CCU99123.1 - 0.14 11.2 0.0 8 5.4 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.6 CCU99123.1 - 0.2 11.7 0.0 0.58 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain STT3 PF02516.14 CCU99124.1 - 1.1e-137 460.0 38.0 3e-137 458.5 38.0 1.6 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 CCU99124.1 - 9.7e-05 22.6 14.8 9.7e-05 22.6 14.8 3.3 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF3405 PF11885.8 CCU99125.1 - 3.1e-83 280.2 11.0 1.1e-52 179.3 1.7 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3405) Cellsynth_D PF03500.13 CCU99126.1 - 0.042 13.7 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 Cellulose synthase subunit D Thioredoxin PF00085.20 CCU99127.1 - 7.1e-27 93.4 0.0 1.7e-25 89.0 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CCU99127.1 - 2.3e-07 31.2 0.1 7.6e-07 29.6 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CCU99127.1 - 0.0015 18.7 0.1 0.012 15.8 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.6 CCU99127.1 - 0.023 15.0 0.0 0.56 10.6 0.0 2.6 1 1 1 2 2 2 0 Thioredoxin-like DUF1456 PF07308.13 CCU99127.1 - 0.14 12.6 0.2 0.63 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Thioredoxin_9 PF14595.6 CCU99127.1 - 0.21 11.3 1.1 0.44 10.3 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin Prenyltrans PF00432.21 CCU99128.1 - 4.7e-29 99.8 14.9 1.6e-07 31.0 0.0 6.3 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CCU99128.1 - 0.0038 16.4 0.0 2.4 7.2 0.0 2.4 1 1 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain Cyclin_N PF00134.23 CCU99131.1 - 7.1e-43 145.4 0.5 1.3e-42 144.6 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCU99131.1 - 4e-24 85.0 0.0 7.2e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain TatD_DNase PF01026.21 CCU99132.1 - 8.7e-23 81.0 0.0 1e-22 80.8 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase NTF2 PF02136.20 CCU99134.1 - 1.3e-28 99.9 0.7 1.9e-28 99.4 0.7 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 CCU99134.1 - 8.4e-08 31.9 0.3 1.7e-07 31.0 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MSA-2c PF12238.8 CCU99134.1 - 3.4 7.6 14.4 0.049 13.6 6.8 1.8 2 0 0 2 2 2 0 Merozoite surface antigen 2c RHD3 PF05879.12 CCU99135.1 - 1.7e-230 767.1 0.0 7.3e-230 765.0 0.0 1.7 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 CCU99135.1 - 8e-05 22.7 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CCU99135.1 - 0.00025 21.1 0.0 0.00046 20.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GBP PF02263.19 CCU99135.1 - 0.00025 20.4 0.1 0.00056 19.3 0.1 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 CCU99135.1 - 0.0014 18.8 0.0 0.0053 17.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain DPBB_1 PF03330.18 CCU99136.1 - 2.1e-07 31.1 0.0 2.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase zf-TFIIB PF13453.6 CCU99136.1 - 0.0016 17.7 0.1 0.0055 16.0 0.1 1.9 1 0 0 1 1 1 1 Transcription factor zinc-finger Cerato-platanin PF07249.12 CCU99136.1 - 0.022 14.9 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Cerato-platanin TIG PF01833.24 CCU99137.1 - 5.7e-12 45.6 5.6 1.3e-11 44.4 2.8 2.8 3 0 0 3 3 3 1 IPT/TIG domain Ank PF00023.30 CCU99137.1 - 4.4e-11 42.7 3.1 0.00022 21.5 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CCU99137.1 - 2.2e-09 37.6 1.2 5.1e-07 30.1 1.8 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCU99137.1 - 5.5e-09 35.5 1.3 0.0021 18.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CCU99137.1 - 6.2e-09 35.9 0.5 4.1e-08 33.3 0.1 2.3 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCU99137.1 - 6e-07 30.0 0.1 1.3e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RHD_dimer PF16179.5 CCU99137.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Rel homology dimerisation domain Glyco_transf_22 PF03901.17 CCU99138.1 - 4.3e-63 214.0 14.0 2.6e-40 139.0 4.8 2.0 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family AAA PF00004.29 CCU99139.1 - 5.7e-14 52.7 0.0 1.2e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCU99139.1 - 1.9e-09 38.2 0.4 1.3e-07 32.1 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCU99139.1 - 1.9e-08 34.6 0.0 3.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 CCU99139.1 - 6.3e-08 32.7 0.1 1.4e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 CCU99139.1 - 0.003 17.9 0.2 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCU99139.1 - 0.0059 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 CCU99139.1 - 0.014 15.4 0.0 0.053 13.5 0.0 2.1 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain NACHT PF05729.12 CCU99139.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 CCU99139.1 - 0.08 13.1 0.1 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain MTHFR PF02219.17 CCU99140.1 - 7.8e-97 324.0 0.0 5.2e-96 321.3 0.0 1.9 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase PDCD2_C PF04194.13 CCU99140.1 - 1e-35 123.4 2.0 7.8e-34 117.3 0.1 2.6 1 1 1 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Glutaredoxin PF00462.24 CCU99141.1 - 4.6e-17 62.0 0.0 6.6e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin zf-C2H2 PF00096.26 CCU99142.1 - 1.1e-05 25.6 9.7 0.0011 19.3 1.9 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCU99142.1 - 0.0067 17.2 11.2 0.0089 16.8 0.9 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCU99142.1 - 0.2 11.7 7.8 0.95 9.5 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CCU99142.1 - 0.51 10.3 8.3 0.17 11.9 2.7 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 CCU99142.1 - 9.7 6.8 11.5 0.79 10.3 0.9 3.0 3 0 0 3 3 3 0 Zinc-finger double domain V-SNARE_C PF12352.8 CCU99143.1 - 1.5e-08 34.8 1.0 3.3e-08 33.7 0.3 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CCU99143.1 - 0.0018 18.2 0.2 0.0073 16.2 0.0 2.1 2 1 1 3 3 3 1 Sec20 Asparaginase_2 PF01112.18 CCU99143.1 - 0.1 11.6 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Asparaginase CRM1_C PF08767.11 CCU99144.1 - 3.8e-131 437.0 0.2 1.7e-129 431.6 0.0 3.3 2 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 CCU99144.1 - 7.4e-39 133.2 0.4 7.4e-39 133.2 0.4 3.7 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CCU99144.1 - 8.4e-33 111.8 3.2 2e-32 110.6 3.2 1.7 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CCU99144.1 - 3e-31 107.3 2.8 9.4e-31 105.7 1.2 2.7 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CCU99144.1 - 5.1e-20 70.7 1.4 1.5e-19 69.2 1.4 1.9 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 CCU99144.1 - 1.6e-14 53.6 0.7 1.6e-14 53.6 0.7 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Zn_peptidase PF04228.13 CCU99144.1 - 0.044 13.2 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Symplekin_C PF12295.8 CCU99144.1 - 0.12 12.5 1.3 2.7 8.1 0.0 3.1 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal Ank_2 PF12796.7 CCU99145.1 - 2e-32 111.6 4.3 2.2e-13 50.6 1.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCU99145.1 - 3.1e-25 88.2 7.4 8.4e-09 35.8 0.1 5.7 2 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCU99145.1 - 5.8e-16 57.0 7.9 0.039 14.5 0.0 7.8 8 0 0 8 8 8 6 Ankyrin repeat SPX PF03105.19 CCU99145.1 - 2.5e-15 57.3 12.5 1.5e-08 35.0 1.2 2.9 2 1 1 3 3 3 2 SPX domain Ank_5 PF13857.6 CCU99145.1 - 7.8e-15 54.8 13.0 6.5e-05 23.1 0.4 7.3 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 CCU99145.1 - 7.1e-14 51.5 14.0 0.0013 19.0 0.0 7.4 6 1 0 6 6 6 4 Ankyrin repeat GDPD PF03009.17 CCU99145.1 - 1e-09 38.5 0.0 2.3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CCDC154 PF15450.6 CCU99145.1 - 4.6 5.7 8.6 0.13 10.8 1.4 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 154 DUF2423 PF10338.9 CCU99146.1 - 3.1e-14 52.9 5.6 3.1e-14 52.9 5.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Pkinase PF00069.25 CCU99147.1 - 2.4e-71 240.2 0.0 2.8e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99147.1 - 5.5e-38 130.7 0.0 6.6e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU99147.1 - 5e-07 29.3 0.0 8.5e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCU99147.1 - 2.6e-05 23.7 0.2 6.3e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CCU99147.1 - 0.00039 19.3 0.4 0.0006 18.7 0.4 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CCU99147.1 - 0.069 13.1 0.1 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 CCU99147.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cpn60_TCP1 PF00118.24 CCU99148.1 - 2.1e-147 491.7 13.4 2.6e-147 491.4 13.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 CCU99148.1 - 2.3e-05 24.0 0.2 0.001 18.6 0.0 2.4 2 0 0 2 2 2 2 Telomere recombination Brix PF04427.18 CCU99149.1 - 2.1e-46 158.5 0.0 2.7e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.13 CCU99149.1 - 0.61 10.0 16.5 0.9 9.5 16.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop25 PF09805.9 CCU99149.1 - 2.6 8.5 17.9 0.27 11.7 13.0 1.9 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Mad3_BUB1_I PF08311.12 CCU99150.1 - 6e-41 139.3 0.1 9.6e-41 138.6 0.1 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 CCU99150.1 - 2.9e-09 36.7 0.0 1.7e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99150.1 - 0.031 13.6 0.0 0.078 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase AFG1_ATPase PF03969.16 CCU99151.1 - 2.4e-88 296.5 0.0 9.8e-84 281.3 0.0 3.0 3 0 0 3 3 3 3 AFG1-like ATPase AAA_16 PF13191.6 CCU99151.1 - 1.1e-05 25.9 0.0 6e-05 23.5 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCU99151.1 - 0.00094 19.5 0.0 0.0055 17.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCU99151.1 - 0.034 14.5 0.0 0.18 12.2 0.0 2.2 2 1 1 3 3 3 0 RNA helicase Vma12 PF11712.8 CCU99152.1 - 1.3e-15 57.7 0.0 1.7e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase cobW PF02492.19 CCU99153.1 - 6.6e-33 113.8 0.1 9.7e-33 113.2 0.0 1.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CCU99153.1 - 0.017 14.1 0.3 0.024 13.6 0.3 1.4 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 CCU99153.1 - 0.042 13.9 0.1 0.67 10.0 0.0 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain zf-Mss51 PF13824.6 CCU99154.1 - 1.4e-22 79.5 1.4 2.3e-22 78.8 1.4 1.3 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 cwf18 PF08315.12 CCU99155.1 - 1.3e-21 77.7 0.9 1.5e-21 77.5 0.9 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor PI3_PI4_kinase PF00454.27 CCU99156.1 - 7.6e-30 104.5 0.0 2.5e-27 96.3 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CCU99156.1 - 1.4e-12 47.4 0.0 2.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CDT1_C PF16679.5 CCU99156.1 - 0.013 15.9 0.2 15 6.1 0.0 3.6 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain Ribosomal_S9 PF00380.19 CCU99157.1 - 3.2e-25 89.0 0.2 6.7e-25 88.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 MotA_ExbB PF01618.16 CCU99157.1 - 0.025 14.3 1.0 0.076 12.8 1.0 1.8 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family DUF4267 PF14087.6 CCU99157.1 - 0.096 12.8 1.7 0.21 11.7 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) Ribosomal_S11 PF00411.19 CCU99158.1 - 1.9e-13 50.8 1.0 3.7e-13 49.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S11 DPM3 PF08285.11 CCU99159.1 - 4.2e-29 100.6 0.1 4.7e-29 100.4 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4229 PF14012.6 CCU99159.1 - 0.67 10.1 6.3 0.41 10.8 4.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4229) Phage_holin_2_2 PF10746.9 CCU99159.1 - 3.6 7.3 7.5 0.96 9.2 3.2 2.0 1 1 1 2 2 2 0 Phage holin T7 family, holin superfamily II Hat1_N PF10394.9 CCU99160.1 - 2.8e-46 157.7 0.0 4.1e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.18 CCU99160.1 - 0.00019 21.1 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_1 PF00583.25 CCU99160.1 - 0.0021 18.3 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TIP41 PF04176.13 CCU99161.1 - 3.1e-45 153.8 0.0 8.2e-45 152.4 0.0 1.6 1 1 0 1 1 1 1 TIP41-like family DLH PF01738.18 CCU99162.1 - 9e-15 54.8 0.0 1e-14 54.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 CCU99164.1 - 2.2e-09 37.2 0.0 2.6e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family RasGEF PF00617.19 CCU99165.1 - 1.3e-51 175.3 0.3 2e-51 174.7 0.3 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CCU99165.1 - 2.8e-23 82.1 0.4 6.8e-23 80.9 0.1 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif Branch PF02485.21 CCU99165.1 - 0.084 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Core-2/I-Branching enzyme WD40 PF00400.32 CCU99166.1 - 3.4e-08 34.0 12.6 0.075 13.9 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Fungus-induced PF10917.8 CCU99166.1 - 0.28 11.5 3.2 0.29 11.5 0.6 2.2 2 0 0 2 2 2 0 Fungus-induced protein MCM PF00493.23 CCU99167.1 - 1.2e-102 341.8 0.0 2e-102 341.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCU99167.1 - 1e-33 115.8 0.1 2e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCU99167.1 - 4.8e-28 97.4 3.0 1.2e-27 96.1 3.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCU99167.1 - 4.7e-12 46.4 0.0 1.2e-11 45.2 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCU99167.1 - 2.5e-06 27.0 0.0 0.00036 20.0 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCU99167.1 - 1.4e-05 25.1 0.0 3.7e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CCU99167.1 - 0.0012 18.7 0.1 0.0061 16.4 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCU99167.1 - 0.054 13.2 0.0 0.77 9.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain RBD-FIP PF09457.10 CCU99167.1 - 0.059 13.3 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 FIP domain Band_7 PF01145.25 CCU99168.1 - 1.2e-19 71.0 0.1 2e-19 70.3 0.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family RA PF00788.23 CCU99169.1 - 3.1e-16 59.8 0.6 6.1e-13 49.2 0.0 3.8 4 0 0 4 4 4 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 CCU99169.1 - 0.029 14.0 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 SH3 domain TUG-UBL1 PF11470.8 CCU99169.1 - 0.088 13.0 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 TUG ubiquitin-like domain Glyco_hydro_20 PF00728.22 CCU99169.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain Chitin_synth_2 PF03142.15 CCU99170.1 - 4.3e-270 896.8 0.3 7.6e-270 896.0 0.3 1.4 1 1 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CCU99170.1 - 3.7e-11 43.4 0.1 8.2e-11 42.2 0.1 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CCU99170.1 - 6.9e-08 32.6 10.5 5.6e-07 29.7 10.5 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 CCU99170.1 - 1.4e-05 24.6 0.1 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CCU99170.1 - 0.0097 15.7 0.0 0.068 13.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 RRM_1 PF00076.22 CCU99171.1 - 3.6e-16 58.7 0.3 7.1e-16 57.8 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCU99171.1 - 3.3e-07 30.0 0.0 3.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CCU99171.1 - 0.036 14.1 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif FIST PF08495.10 CCU99172.1 - 3.9e-05 23.7 0.0 6.1e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 FIST N domain PrpF PF04303.13 CCU99173.1 - 2e-52 178.4 1.9 7.5e-36 123.9 0.4 2.6 2 1 0 2 2 2 2 PrpF protein HoxA13_N PF12284.8 CCU99173.1 - 0.22 12.2 2.9 0.33 11.6 0.8 2.3 2 0 0 2 2 2 0 Hox protein A13 N terminal GDP_Man_Dehyd PF16363.5 CCU99174.1 - 2.9e-50 171.6 0.0 3.3e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CCU99174.1 - 2.8e-43 148.1 0.0 3.3e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCU99174.1 - 6.9e-11 41.7 0.0 2e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CCU99174.1 - 2.5e-10 40.0 0.0 4.8e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CCU99174.1 - 2.3e-07 30.3 0.0 1.4e-06 27.7 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CCU99174.1 - 1e-05 25.5 0.1 0.0001 22.3 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CCU99174.1 - 1e-05 25.5 0.0 3.8e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 CCU99174.1 - 0.00013 21.2 0.0 0.00038 19.7 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein 3HCDH_N PF02737.18 CCU99174.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RPA_interact_C PF14768.6 CCU99176.1 - 0.0064 17.0 0.0 0.01 16.4 0.0 1.3 1 0 0 1 1 1 1 Replication protein A interacting C-terminal Ribosomal_L11 PF00298.19 CCU99177.1 - 5.8e-17 62.0 0.2 9.9e-17 61.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 CCU99177.1 - 2.9e-07 30.2 0.0 6.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain WD40 PF00400.32 CCU99178.1 - 1.9e-44 148.8 21.3 2.8e-09 37.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU99178.1 - 3.7e-12 46.4 0.4 0.033 14.5 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCU99178.1 - 0.00023 19.9 4.3 0.097 11.3 0.1 3.9 2 1 0 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 CCU99178.1 - 0.0014 18.6 1.2 22 5.2 0.0 5.1 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 CCU99178.1 - 0.013 14.0 0.0 0.57 8.6 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 CCU99178.1 - 0.019 13.9 0.1 20 4.0 0.0 4.0 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RRM_1 PF00076.22 CCU99179.1 - 4.2e-22 77.7 0.0 5.6e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCU99179.1 - 0.015 15.4 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 CCU99179.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif Glyoxal_oxid_N PF07250.11 CCU99180.1 - 1e-24 87.1 0.0 5.8e-12 45.3 0.0 4.7 3 1 2 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CCU99180.1 - 2.7e-20 72.5 0.1 5.3e-20 71.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Podoplanin PF05808.11 CCU99180.1 - 1.3e-05 25.3 0.0 3.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 CCU99180.1 - 0.0017 17.7 1.7 0.0035 16.7 1.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CYYR1 PF10873.8 CCU99180.1 - 0.064 13.7 0.0 0.064 13.7 0.0 2.2 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 EphA2_TM PF14575.6 CCU99180.1 - 0.079 13.9 0.0 0.17 12.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Kelch_2 PF07646.15 CCU99180.1 - 0.12 12.4 5.3 76 3.5 0.0 5.1 5 0 0 5 5 5 0 Kelch motif DUF4690 PF15756.5 CCU99180.1 - 0.14 12.7 0.0 1.3 9.7 0.0 2.7 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Kelch_4 PF13418.6 CCU99180.1 - 0.87 9.6 4.6 7.9 6.6 0.1 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Sec23_trunk PF04811.15 CCU99181.1 - 9.3e-59 198.9 0.0 1.5e-58 198.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Mito_carr PF00153.27 CCU99181.1 - 1.6e-52 175.4 0.9 2.1e-22 78.8 0.0 3.9 4 0 0 4 4 4 3 Mitochondrial carrier protein Sec23_helical PF04815.15 CCU99181.1 - 2.9e-25 88.1 0.0 5.4e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CCU99181.1 - 1.3e-16 61.1 0.0 3.2e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CCU99181.1 - 8.5e-15 54.5 5.5 1.8e-14 53.5 5.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CCU99181.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 Gelsolin repeat Thymidylat_synt PF00303.19 CCU99182.1 - 7.5e-102 340.0 0.0 1e-101 339.6 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.22 CCU99182.1 - 6.6e-35 120.6 0.0 1.3e-34 119.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CLLAC PF15675.5 CCU99183.1 - 0.32 10.6 5.0 0.59 9.7 5.0 1.4 1 0 0 1 1 1 0 CLLAC-motif containing domain zf-MYND PF01753.18 CCU99184.1 - 3e-07 30.4 14.9 6.5e-07 29.3 14.9 1.6 1 0 0 1 1 1 1 MYND finger Mur_ligase_M PF08245.12 CCU99185.1 - 0.22 11.5 0.0 0.33 10.9 0.0 1.4 1 1 0 1 1 1 0 Mur ligase middle domain tRNA_anti-codon PF01336.25 CCU99187.1 - 7.3e-11 41.9 0.1 1.7e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 CCU99187.1 - 5.4e-05 23.0 0.1 6.5e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 AAA PF00004.29 CCU99189.1 - 1.8e-40 138.4 0.0 3e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CCU99189.1 - 2.2e-12 46.7 0.1 4.8e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 CCU99189.1 - 1.2e-05 25.6 0.4 0.01 16.1 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CCU99189.1 - 2.8e-05 24.3 0.0 4.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CCU99189.1 - 4.6e-05 22.7 0.0 0.0001 21.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CCU99189.1 - 0.00012 22.0 0.3 0.001 19.1 0.2 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CCU99189.1 - 0.00023 21.4 0.4 0.092 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCU99189.1 - 0.00043 20.7 0.5 0.0073 16.7 0.5 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CCU99189.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CCU99189.1 - 0.0049 17.4 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCU99189.1 - 0.0054 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CCU99189.1 - 0.0097 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CCU99189.1 - 0.011 15.1 0.1 0.24 10.7 0.1 2.2 1 1 1 2 2 2 0 KaiC Prot_ATP_OB_N PF17758.1 CCU99189.1 - 0.011 15.3 0.1 0.055 13.1 0.0 2.2 3 0 0 3 3 3 0 Proteasomal ATPase OB N-terminal domain AAA_14 PF13173.6 CCU99189.1 - 0.014 15.4 0.0 0.062 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CCU99189.1 - 0.021 14.5 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 CCU99189.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NB-ARC PF00931.22 CCU99189.1 - 0.091 11.9 0.1 0.6 9.2 0.0 2.2 3 0 0 3 3 3 0 NB-ARC domain RNA_helicase PF00910.22 CCU99189.1 - 0.093 13.1 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 CCU99189.1 - 0.1 12.1 0.6 2.7 7.5 0.2 2.3 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 CCU99189.1 - 0.12 11.6 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 CCU99189.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CCU99189.1 - 0.17 11.6 0.3 0.35 10.6 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CCU99189.1 - 0.19 11.4 0.2 0.4 10.4 0.1 1.5 2 0 0 2 2 1 0 AAA domain Tim17 PF02466.19 CCU99190.1 - 7.2e-34 116.5 10.4 1.6e-33 115.4 10.4 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family E1-E2_ATPase PF00122.20 CCU99191.1 - 3.4e-41 140.8 9.2 5.4e-40 136.8 2.8 3.4 3 1 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 CCU99191.1 - 1.6e-18 67.8 0.1 2.9e-18 66.9 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCU99191.1 - 1.9e-09 37.0 0.0 4.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCU99191.1 - 0.0018 18.1 0.1 0.0042 16.8 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCU99191.1 - 0.0083 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cpn60_TCP1 PF00118.24 CCU99193.1 - 8.8e-166 552.3 2.7 1e-165 552.2 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1572 PF07609.11 CCU99193.1 - 0.061 13.1 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) PMG PF05287.12 CCU99194.1 - 0.009 16.1 0.9 0.009 16.1 0.9 2.3 2 0 0 2 2 2 1 PMG protein SNF2_N PF00176.23 CCU99195.1 - 1.5e-56 191.6 0.0 2.9e-55 187.4 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCU99195.1 - 3.7e-15 56.2 0.0 1.1e-14 54.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU99195.1 - 2.8e-08 34.0 0.0 4.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 CCU99195.1 - 4e-08 33.0 3.0 4e-08 33.0 3.0 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCU99195.1 - 1.4e-06 28.0 2.2 1.4e-06 28.0 2.2 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCU99195.1 - 3.2e-05 23.9 0.4 3.2e-05 23.9 0.4 2.6 2 2 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CCU99195.1 - 0.00013 21.8 6.6 0.00013 21.8 6.6 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCU99195.1 - 0.00016 21.9 5.6 0.00016 21.9 5.6 2.7 2 1 0 2 2 1 1 Ring finger domain DEAD PF00270.29 CCU99195.1 - 0.00042 20.1 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 CCU99195.1 - 0.0012 18.8 3.6 0.0012 18.8 3.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CCU99195.1 - 0.0079 16.3 2.3 0.0079 16.3 2.3 2.7 2 2 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CCU99195.1 - 0.009 15.8 5.8 0.009 15.8 5.8 2.6 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CCU99195.1 - 0.1 12.4 1.4 0.25 11.2 1.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS91 PF14319.6 CCU99195.1 - 3.7 7.6 11.8 1.5 8.9 1.2 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain HTH_20 PF12840.7 CCU99196.1 - 0.029 14.4 0.0 3.9 7.6 0.0 4.1 3 1 0 3 3 3 0 Helix-turn-helix domain HEAT_EZ PF13513.6 CCU99196.1 - 0.51 10.9 9.0 1.3 9.6 0.2 4.7 4 0 0 4 4 4 0 HEAT-like repeat CAF1C_H4-bd PF12265.8 CCU99197.1 - 3.8e-29 100.7 0.2 9.5e-29 99.5 0.2 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CCU99197.1 - 6.4e-27 93.3 7.8 6.3e-05 23.7 0.3 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU99197.1 - 0.00058 20.1 1.7 0.18 12.1 0.1 4.3 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCU99197.1 - 0.069 11.8 0.3 1.7 7.2 0.0 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DEAD PF00270.29 CCU99198.1 - 1e-42 145.9 0.1 1.6e-42 145.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU99198.1 - 3.5e-27 94.9 0.7 7.3e-27 93.9 0.3 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CCU99198.1 - 0.0036 16.7 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 CCU99198.1 - 0.016 15.2 0.0 0.039 13.9 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Pam17 PF08566.10 CCU99199.1 - 5.5e-56 189.0 0.0 6.5e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DnaJ PF00226.31 CCU99200.1 - 4.5e-14 52.3 0.3 8.7e-14 51.4 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain RrnaAD PF00398.20 CCU99201.1 - 2.2e-19 69.5 0.0 3.2e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PBP PF01161.20 CCU99202.1 - 4.5e-16 59.4 0.2 8e-16 58.6 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ATG11 PF10377.9 CCU99203.1 - 6.8e-23 81.1 0.0 1.6e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein 11 APG17 PF04108.12 CCU99203.1 - 1.5e-05 24.3 8.1 0.0082 15.3 1.8 3.6 2 1 1 3 3 3 2 Autophagy protein Apg17 Baculo_PEP_C PF04513.12 CCU99203.1 - 0.0067 16.5 4.4 0.084 12.9 0.1 3.8 4 1 0 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 CCU99203.1 - 0.078 13.3 4.6 4.8 7.6 0.1 4.5 4 1 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HAP1_N PF04849.13 CCU99203.1 - 0.13 11.5 4.2 0.12 11.6 0.4 2.5 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF3584 PF12128.8 CCU99203.1 - 0.15 9.6 5.2 0.23 8.9 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Tup_N PF08581.10 CCU99203.1 - 0.24 11.7 5.5 28 5.1 0.0 4.1 4 0 0 4 4 4 0 Tup N-terminal DUF1664 PF07889.12 CCU99203.1 - 0.37 10.8 1.1 30 4.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 CCU99203.1 - 4.9 7.2 7.5 33 4.6 0.0 3.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Wtap PF17098.5 CCU99203.1 - 7.3 6.5 8.2 20 5.1 0.4 3.2 3 0 0 3 3 3 0 WTAP/Mum2p family Fip1 PF05182.13 CCU99204.1 - 1.6e-20 72.4 0.3 2.8e-20 71.6 0.3 1.4 1 0 0 1 1 1 1 Fip1 motif MPC PF03650.13 CCU99205.1 - 1.9e-30 105.2 0.3 2.1e-30 105.1 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Glyoxalase PF00903.25 CCU99206.1 - 6.1 7.0 9.6 2.1 8.6 6.5 2.0 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RNase_P_p30 PF01876.16 CCU99207.1 - 3.2e-41 141.2 0.0 8.1e-41 139.8 0.0 1.7 1 1 0 1 1 1 1 RNase P subunit p30 Hydrolase_6 PF13344.6 CCU99207.1 - 0.18 11.9 0.2 27 4.9 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Peptidase_M50B PF13398.6 CCU99208.1 - 6.7e-37 127.1 5.1 8.9e-37 126.7 5.1 1.0 1 0 0 1 1 1 1 Peptidase M50B-like DUF4131 PF13567.6 CCU99208.1 - 4.2 7.0 6.5 1 9.0 2.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4922 PF16269.5 CCU99209.1 - 0.089 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) Rad51 PF08423.11 CCU99210.1 - 5.6e-60 202.8 3.1 2.8e-53 180.8 0.1 2.2 1 1 1 2 2 2 2 Rad51 HHH_5 PF14520.6 CCU99210.1 - 2.4e-05 24.8 0.0 4.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_25 PF13481.6 CCU99210.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 CCU99210.1 - 0.025 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Elong_Iki1 PF10483.9 CCU99210.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 RecA PF00154.21 CCU99210.1 - 0.11 11.9 0.5 11 5.4 0.0 2.2 1 1 1 2 2 2 0 recA bacterial DNA recombination protein Rad1 PF02144.16 CCU99211.1 - 5.9e-60 202.7 0.0 6.7e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 WD40 PF00400.32 CCU99212.1 - 2.8e-16 59.6 5.1 1e-09 38.8 0.0 4.5 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU99212.1 - 0.00054 20.2 0.0 0.03 14.6 0.0 2.9 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCU99212.1 - 0.0065 15.5 0.0 0.025 13.5 0.0 2.0 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CCU99212.1 - 0.12 10.9 0.0 8.5 4.9 0.0 2.8 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Chitin_synth_2 PF03142.15 CCU99213.1 - 7.4e-227 754.1 0.0 1e-226 753.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CCU99213.1 - 6.9e-80 269.1 0.0 2.5e-79 267.3 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.6 CCU99213.1 - 4.2e-15 56.3 0.3 1.3e-11 44.9 0.0 3.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 DEK_C PF08766.11 CCU99213.1 - 8.7e-14 51.2 0.0 2.5e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 CCU99213.1 - 2.7e-10 40.3 0.0 1.2e-08 34.9 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 CCU99213.1 - 4.6e-10 39.7 3.7 4.6e-10 39.7 3.7 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CCU99213.1 - 2.4e-05 24.2 0.0 0.0084 15.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CCU99213.1 - 0.0015 18.1 0.0 0.04 13.4 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 21 HTH_16 PF12645.7 CCU99213.1 - 0.024 14.7 0.1 11 6.1 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_16 PF13191.6 CCU99213.1 - 0.15 12.4 0.8 13 6.1 0.1 3.1 2 1 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.25 CCU99214.1 - 2.1e-62 210.9 0.0 2.4e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99214.1 - 2.8e-28 98.9 0.0 3.9e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCU99214.1 - 0.00016 21.1 0.1 0.0003 20.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CCU99214.1 - 0.00041 20.0 0.1 0.0016 18.1 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CCU99214.1 - 0.0039 17.1 0.4 0.058 13.3 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCU99214.1 - 0.0044 15.9 0.0 0.0058 15.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CCU99214.1 - 0.006 15.6 0.1 0.014 14.4 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 CCU99214.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CCU99214.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like YukC PF10140.9 CCU99214.1 - 0.038 12.8 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Seadorna_VP7 PF07387.11 CCU99214.1 - 0.18 10.9 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Sel1 PF08238.12 CCU99215.1 - 9.9e-12 45.1 19.1 4.8e-07 30.2 0.0 6.2 6 0 0 6 6 6 2 Sel1 repeat TPR_2 PF07719.17 CCU99215.1 - 0.032 14.4 5.5 0.14 12.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCU99215.1 - 0.054 13.7 1.8 0.18 12.1 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCU99215.1 - 1 10.1 3.9 5.3 7.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCU99215.1 - 2.2 8.3 4.0 3.1 7.8 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat eIF-5a PF01287.20 CCU99216.1 - 1.8e-29 101.6 0.2 2.5e-29 101.2 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CCU99216.1 - 0.026 14.6 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain HLH PF00010.26 CCU99217.1 - 4e-14 52.3 0.1 7.8e-14 51.4 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TolA_bind_tri PF16331.5 CCU99217.1 - 0.023 14.7 1.3 0.063 13.4 1.3 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation NAD_binding_7 PF13241.6 CCU99218.1 - 2.3e-27 95.5 0.0 3.2e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 CCU99218.1 - 4.1e-15 54.9 0.8 8.4e-15 53.9 0.8 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 CCU99218.1 - 2.3e-12 46.4 0.0 3.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal TrkA_N PF02254.18 CCU99218.1 - 0.069 13.4 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 CCU99218.1 - 0.083 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Telomere_reg-2 PF10193.9 CCU99219.1 - 9.2e-28 96.9 0.0 2.3e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein zf-HC5HC2H_2 PF13832.6 CCU99219.1 - 0.068 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain Pil1 PF13805.6 CCU99220.1 - 7.1e-27 94.6 4.2 1e-26 94.0 4.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2730 PF10805.8 CCU99220.1 - 0.011 15.8 0.3 0.028 14.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF3287 PF11690.8 CCU99220.1 - 0.1 12.3 0.2 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Gp-FAR-1 PF05823.12 CCU99220.1 - 0.11 12.9 0.3 0.22 11.9 0.3 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2203 PF09969.9 CCU99220.1 - 0.19 12.4 0.4 0.66 10.7 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) BLOC1_2 PF10046.9 CCU99220.1 - 0.71 10.2 3.4 0.35 11.2 0.8 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribonuc_P_40 PF08584.11 CCU99221.1 - 8.4e-46 156.5 0.0 2e-45 155.3 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit NIPSNAP PF07978.13 CCU99222.1 - 2.2e-08 34.2 1.8 0.00033 20.8 0.1 2.3 2 1 0 2 2 2 2 NIPSNAP Katanin_con80 PF13925.6 CCU99222.1 - 0.22 11.6 0.2 0.3 11.1 0.2 1.1 1 0 0 1 1 1 0 con80 domain of Katanin TEA PF01285.18 CCU99223.1 - 8.4e-30 102.7 0.0 1.7e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain FeS_assembly_P PF01883.19 CCU99224.1 - 1.1e-12 47.9 0.0 3e-12 46.5 0.0 1.8 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Sec1 PF00995.23 CCU99225.1 - 6.1e-102 342.7 0.0 7.6e-102 342.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3182 PF11379.8 CCU99225.1 - 0.044 12.7 0.0 0.073 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) 4HBT PF03061.22 CCU99225.1 - 0.12 12.8 2.3 0.22 11.9 0.2 2.5 2 0 0 2 2 2 0 Thioesterase superfamily tRNA-synt_1e PF01406.19 CCU99226.1 - 1.3e-123 412.2 0.0 1.9e-123 411.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CCU99226.1 - 1.7e-08 33.7 0.3 0.00023 20.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 CCU99226.1 - 3e-05 24.4 1.8 8.3e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.21 CCU99226.1 - 9.4e-05 21.4 0.1 0.0027 16.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1 PF00133.22 CCU99226.1 - 0.00087 17.7 0.0 0.034 12.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DUF1887 PF09002.11 CCU99226.1 - 0.013 14.2 0.3 0.025 13.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) tRNA-synt_1f PF01921.18 CCU99226.1 - 0.12 11.2 0.0 13 4.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) EGL-1 PF11430.8 CCU99226.1 - 0.62 10.0 2.8 1.3 9.0 2.8 1.5 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 Methyltransf_16 PF10294.9 CCU99227.1 - 3.1e-43 147.5 0.0 3.8e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CCU99227.1 - 0.0066 16.3 0.0 0.0091 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Exo_endo_phos PF03372.23 CCU99228.1 - 4.6e-09 36.1 0.0 1.4e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LUC7 PF03194.15 CCU99229.1 - 5.6e-71 239.2 2.7 6.5e-71 238.9 2.7 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF3161 PF11362.8 CCU99229.1 - 0.028 14.4 0.0 0.077 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3161) Phage_HK97_TLTM PF06120.11 CCU99229.1 - 0.036 13.2 1.0 0.05 12.8 1.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Syntaxin_2 PF14523.6 CCU99229.1 - 0.043 14.2 1.8 0.14 12.5 1.0 2.0 2 0 0 2 2 2 0 Syntaxin-like protein DUF4349 PF14257.6 CCU99229.1 - 0.043 13.3 4.1 0.069 12.6 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) AAA_13 PF13166.6 CCU99229.1 - 0.05 12.3 4.9 0.35 9.5 5.1 1.8 1 1 0 1 1 1 0 AAA domain FapA PF03961.13 CCU99229.1 - 0.077 11.6 4.1 0.059 12.0 3.1 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Prominin PF05478.11 CCU99229.1 - 0.1 10.5 1.5 0.1 10.5 0.7 1.4 2 0 0 2 2 2 0 Prominin V_ATPase_I PF01496.19 CCU99229.1 - 0.25 9.2 2.5 0.28 9.0 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ly49 PF08391.10 CCU99229.1 - 0.32 11.4 5.6 3 8.2 2.7 2.1 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region BLOC1_2 PF10046.9 CCU99229.1 - 0.34 11.2 3.9 0.44 10.9 0.7 2.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GvpL_GvpF PF06386.11 CCU99229.1 - 0.38 10.7 3.9 0.37 10.7 2.8 1.5 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PCRF PF03462.18 CCU99229.1 - 0.54 10.1 5.0 0.37 10.6 3.5 1.4 2 0 0 2 2 2 0 PCRF domain PRKG1_interact PF15898.5 CCU99229.1 - 3.3 8.6 10.9 31 5.5 7.8 2.9 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Thymidylate_kin PF02223.17 CCU99230.1 - 1.4e-40 138.9 0.0 2.1e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 CCU99230.1 - 0.072 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Abhydro_lipase PF04083.16 CCU99230.1 - 0.082 12.5 0.1 21 4.8 0.0 2.7 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region AAA_33 PF13671.6 CCU99230.1 - 0.085 13.0 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain FSH1 PF03959.13 CCU99230.1 - 0.17 11.5 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) CSTF2_hinge PF14327.6 CCU99231.1 - 3.8e-30 104.2 0.8 3.8e-30 104.2 0.8 2.0 2 1 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 CCU99231.1 - 9.4e-16 57.1 11.3 5.6e-15 54.6 7.7 2.4 2 0 0 2 2 2 2 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.22 CCU99231.1 - 0.0006 19.6 0.1 0.0011 18.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prefoldin_2 PF01920.20 CCU99232.1 - 1.2e-13 50.9 2.3 1.4e-13 50.7 2.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit B56 PF01603.20 CCU99233.1 - 1e-181 604.5 7.1 1.3e-181 604.1 7.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Herpes_HEPA PF03324.14 CCU99233.1 - 0.042 14.3 0.1 0.23 12.0 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus DNA helicase/primase complex associated protein Sec7_N PF12783.7 CCU99233.1 - 0.51 10.2 3.0 3.4 7.6 0.4 2.4 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec66 PF09802.9 CCU99234.1 - 2.7e-35 121.6 0.5 3.2e-35 121.3 0.5 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Transket_pyr PF02779.24 CCU99236.1 - 3.6e-41 140.8 0.1 3.4e-40 137.6 0.1 2.1 1 1 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CCU99236.1 - 7e-40 135.8 0.0 1.5e-39 134.7 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CCU99236.1 - 0.028 14.7 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II Pyrophosphatase PF00719.19 CCU99237.1 - 2.5e-58 196.4 0.2 3.4e-58 196.0 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase peroxidase PF00141.23 CCU99238.1 - 2.6e-45 154.9 0.0 3.8e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4003 PF13170.6 CCU99238.1 - 0.03 13.7 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Arrestin_C PF02752.22 CCU99239.1 - 0.0021 18.5 0.0 0.019 15.4 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 CCU99239.1 - 0.0023 17.2 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 Rgp1 E1-E2_ATPase PF00122.20 CCU99241.1 - 9e-52 175.2 0.7 9e-52 175.2 0.7 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CCU99241.1 - 9.9e-49 165.5 5.9 3.4e-48 163.8 4.0 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CCU99241.1 - 7.6e-22 78.6 2.9 3.6e-21 76.4 2.9 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCU99241.1 - 6.5e-18 64.2 0.1 1.6e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CCU99241.1 - 5.1e-17 61.7 0.0 1e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCU99241.1 - 2.2e-09 37.4 0.7 7.1e-07 29.2 1.3 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CCU99241.1 - 8.1e-06 26.4 0.0 1.8e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DeoRC PF00455.22 CCU99241.1 - 0.0065 16.4 0.3 0.02 14.9 0.3 1.8 1 0 0 1 1 1 1 DeoR C terminal sensor domain Proteasome_A_N PF10584.9 CCU99241.1 - 0.075 12.7 0.1 0.19 11.4 0.1 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature L31 PF09784.9 CCU99242.1 - 6.2e-40 135.8 0.2 7e-40 135.6 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 F_bP_aldolase PF01116.20 CCU99243.1 - 6.3e-95 317.8 0.0 7.1e-95 317.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Vac_ImportDeg PF09783.9 CCU99244.1 - 3.9e-23 82.0 0.0 7.1e-20 71.4 0.0 2.3 1 1 1 2 2 2 2 Vacuolar import and degradation protein Fasciclin PF02469.22 CCU99245.1 - 1e-54 184.1 0.0 6e-14 52.4 0.0 5.7 5 2 0 5 5 5 5 Fasciclin domain Radical_SAM_C PF16199.5 CCU99246.1 - 5.4e-31 106.5 0.0 1.6e-30 105.0 0.0 1.8 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CCU99246.1 - 4.2e-17 63.0 0.3 1.2e-16 61.5 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CCU99246.1 - 2.5e-08 34.2 0.0 4.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCU99246.1 - 2.1e-06 27.7 0.0 4.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCU99246.1 - 0.012 16.0 0.1 0.031 14.7 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCU99246.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Myotub-related PF06602.14 CCU99247.1 - 4.5e-134 446.8 0.0 5.9e-134 446.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 CCU99247.1 - 0.0044 16.8 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCU99247.1 - 0.0049 16.5 0.1 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CCU99247.1 - 0.015 15.2 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family HTH_29 PF13551.6 CCU99247.1 - 0.027 14.5 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix LRR_6 PF13516.6 CCU99248.1 - 3.2e-11 42.4 12.5 0.5 10.6 1.3 7.5 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 CCU99248.1 - 0.00014 22.2 14.6 6 7.4 0.1 6.3 4 3 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CCU99248.1 - 0.008 16.6 7.6 11 7.0 0.3 6.6 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 CCU99248.1 - 0.015 15.0 14.2 2.8 7.8 0.1 5.9 6 1 0 6 6 6 0 Leucine rich repeat GCIP PF13324.6 CCU99248.1 - 1.1 8.8 11.9 2.6 7.6 11.9 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 CCU99248.1 - 1.7 7.9 9.9 2.7 7.3 9.9 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 CCU99248.1 - 4.5 5.3 13.3 6.3 4.8 13.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Lactamase_B_2 PF12706.7 CCU99249.1 - 4.6e-25 88.3 0.0 8.6e-24 84.2 0.0 2.2 1 1 1 2 2 2 1 Beta-lactamase superfamily domain adh_short PF00106.25 CCU99249.1 - 5.7e-12 45.5 0.0 1.2e-11 44.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCU99249.1 - 1.6e-07 31.2 0.2 6.6e-06 25.8 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Lactamase_B PF00753.27 CCU99249.1 - 2e-07 31.2 0.1 3.6e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 CCU99249.1 - 0.016 14.6 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain WD40 PF00400.32 CCU99250.1 - 6.7e-17 61.6 1.4 0.0011 19.8 0.1 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_2 PF13360.6 CCU99250.1 - 2.2e-06 27.4 1.0 1.9e-05 24.4 0.2 2.2 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 CCU99250.1 - 2.3e-05 24.7 7.3 0.48 11.0 0.0 4.6 5 1 0 5 5 5 3 PQQ-like domain PQQ PF01011.21 CCU99250.1 - 0.00017 21.4 3.4 0.56 10.2 0.0 3.8 4 0 0 4 4 4 2 PQQ enzyme repeat ANAPC4_WD40 PF12894.7 CCU99250.1 - 0.00026 21.2 0.0 5.5 7.4 0.0 3.7 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 CCU99250.1 - 0.06 12.8 0.3 0.2 11.1 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) FMO-like PF00743.19 CCU99251.1 - 1.8e-11 43.2 0.0 1.2e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CCU99251.1 - 0.00042 19.7 0.0 0.0065 15.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CCU99251.1 - 0.032 13.4 0.0 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF295 PF03478.18 CCU99251.1 - 0.13 11.9 0.2 12 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF295) Pkinase PF00069.25 CCU99252.1 - 8.9e-26 90.8 0.0 1.1e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99252.1 - 8.7e-12 44.9 0.0 1.2e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCU99252.1 - 1.2e-07 30.8 0.1 1.8e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CCU99252.1 - 0.018 15.0 0.0 1.8 8.4 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-Tim10_DDP PF02953.15 CCU99253.1 - 1.9e-19 69.0 0.4 2.5e-19 68.7 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3782 PF12644.7 CCU99253.1 - 0.043 14.0 0.1 0.1 12.8 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) DNA_pol_phi PF04931.13 CCU99254.1 - 1.1e-213 711.5 2.1 2.4e-213 710.5 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase phi 3HCDH_RFF PF18321.1 CCU99254.1 - 0.017 15.5 0.3 0.13 12.8 0.0 2.7 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Med17 PF10156.9 CCU99254.1 - 0.044 12.5 4.2 0.081 11.6 4.2 1.4 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Rhodanese PF00581.20 CCU99255.1 - 9.1e-10 39.0 0.0 1.8e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain PUF PF00806.19 CCU99257.1 - 2.7e-19 67.7 0.0 0.0022 17.6 0.0 4.7 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat DUF3400 PF11880.8 CCU99257.1 - 0.00072 19.0 0.0 0.0049 16.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3400) Spc24 PF08286.11 CCU99261.1 - 2.8e-05 24.3 1.1 2.8e-05 24.3 1.1 2.3 2 1 0 2 2 2 1 Spc24 subunit of Ndc80 F_actin_bind PF08919.10 CCU99261.1 - 0.004 17.2 1.9 0.013 15.6 2.0 1.9 1 1 0 1 1 1 1 F-actin binding GAS PF13851.6 CCU99261.1 - 0.008 15.5 10.5 0.01 15.2 10.5 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 CCU99261.1 - 0.027 13.9 11.7 0.035 13.6 11.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Bacillus_HBL PF05791.11 CCU99261.1 - 0.028 14.2 2.8 0.038 13.8 2.8 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) MAD PF05557.13 CCU99261.1 - 0.037 12.4 11.3 0.047 12.1 11.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Spc7 PF08317.11 CCU99261.1 - 0.067 12.1 8.3 0.08 11.8 8.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FAM76 PF16046.5 CCU99261.1 - 0.091 12.1 5.5 0.12 11.7 5.5 1.1 1 0 0 1 1 1 0 FAM76 protein JAKMIP_CC3 PF16034.5 CCU99261.1 - 0.2 11.6 11.0 0.4 10.6 11.0 1.5 1 1 0 1 1 1 0 JAKMIP CC3 domain TMPIT PF07851.13 CCU99261.1 - 0.24 10.6 3.7 0.33 10.2 3.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein Laminin_II PF06009.12 CCU99261.1 - 0.27 11.2 5.5 0.4 10.7 5.5 1.2 1 0 0 1 1 1 0 Laminin Domain II FapA PF03961.13 CCU99261.1 - 0.3 9.7 3.8 0.34 9.4 3.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A BCAS2 PF05700.11 CCU99261.1 - 0.41 10.3 7.7 0.54 9.9 5.6 1.9 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) BLOC1_2 PF10046.9 CCU99261.1 - 0.41 11.0 7.9 1.4 9.3 0.6 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 CCU99261.1 - 0.42 10.8 5.7 2.9 8.1 5.7 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ZapD PF07072.11 CCU99261.1 - 1 9.1 7.6 5.8 6.6 0.6 2.1 1 1 1 2 2 2 0 Cell division protein RAP80_UIM PF18282.1 CCU99261.1 - 1.3 8.9 9.2 0.27 11.0 4.3 2.2 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif DUF1515 PF07439.11 CCU99261.1 - 1.4 8.9 5.8 1.2 9.2 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) FlaC_arch PF05377.11 CCU99261.1 - 2.4 8.6 7.8 0.74 10.3 1.1 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 CCU99261.1 - 2.5 8.2 7.0 5.9 7.0 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 CCU99261.1 - 2.8 7.8 7.6 2.1 8.2 2.1 2.6 1 1 2 3 3 3 0 Septum formation initiator Med9 PF07544.13 CCU99261.1 - 3.6 7.7 9.5 5.9 7.0 1.4 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ACCA PF03255.14 CCU99261.1 - 4.7 7.1 8.3 7 6.5 1.0 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit APG6_N PF17675.1 CCU99261.1 - 5.4 7.6 14.3 12 6.4 11.0 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Rep_fac_C PF08542.11 CCU99263.1 - 3.5e-10 40.2 0.1 1.5e-09 38.1 0.1 2.2 2 1 0 2 2 2 1 Replication factor C C-terminal domain AAA_assoc_2 PF16193.5 CCU99263.1 - 0.00019 21.7 0.0 0.00046 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain Ribosomal_S6 PF01250.17 CCU99263.1 - 0.035 14.4 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S6 AA_kinase PF00696.28 CCU99264.1 - 4.5e-39 134.5 0.3 5.7e-39 134.1 0.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 CCU99264.1 - 7.5e-15 54.7 0.1 3.1e-13 49.5 0.0 2.4 2 0 0 2 2 2 1 PUA domain WD40 PF00400.32 CCU99265.1 - 7.5e-09 36.1 9.0 0.066 14.1 0.0 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU99265.1 - 1.6e-05 25.1 0.1 0.0048 17.2 0.0 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CCU99265.1 - 0.0006 20.2 0.3 0.02 15.3 0.0 3.8 3 0 0 3 3 3 1 PQQ-like domain DEAD PF00270.29 CCU99266.1 - 7.5e-36 123.5 0.0 1.2e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU99266.1 - 6.4e-31 107.0 0.0 5.2e-29 100.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU99266.1 - 2.1e-06 27.8 0.0 3.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCU99266.1 - 0.76 10.0 2.8 4.1 7.7 1.5 2.8 2 1 0 2 2 2 0 AAA domain Homeodomain PF00046.29 CCU99267.1 - 0.025 14.4 0.9 0.045 13.6 0.2 1.8 1 1 0 1 1 1 0 Homeodomain CTP_transf_like PF01467.26 CCU99268.1 - 5.7e-28 97.9 0.0 6.7e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Helicase_C PF00271.31 CCU99269.1 - 6.9e-19 68.2 0.1 2.4e-18 66.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCU99269.1 - 2.1e-15 56.9 3.1 2.2e-15 56.9 0.1 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CCU99269.1 - 0.013 14.7 0.3 0.023 13.9 0.0 1.4 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Toxin_YhaV PF11663.8 CCU99269.1 - 0.091 12.8 0.0 18 5.4 0.0 2.3 2 0 0 2 2 2 0 Toxin with endonuclease activity, of toxin-antitoxin system ORC_WH_C PF18137.1 CCU99270.1 - 7.7e-29 100.6 0.1 4.4e-27 94.9 0.0 2.9 2 1 0 2 2 2 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 CCU99270.1 - 2.1e-08 33.7 0.2 0.0027 16.9 0.0 3.4 3 0 0 3 3 3 3 Origin recognition complex (ORC) subunit 3 N-terminus RE_TaqI PF09573.10 CCU99270.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 TaqI restriction endonuclease Mito_carr PF00153.27 CCU99271.1 - 9.7e-43 144.0 1.1 3.5e-15 55.7 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Heliorhodopsin PF18761.1 CCU99271.1 - 0.048 13.0 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Heliorhodopsin Cucumo_2B PF03263.13 CCU99271.1 - 0.068 13.6 0.1 0.14 12.7 0.1 1.4 1 0 0 1 1 1 0 Cucumovirus protein 2B NPR2 PF06218.11 CCU99272.1 - 4e-73 246.6 6.1 6e-34 117.6 0.4 3.3 2 1 1 3 3 3 3 Nitrogen permease regulator 2 NPR3 PF03666.13 CCU99272.1 - 0.00049 19.0 0.1 0.0016 17.3 0.0 1.8 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_M28 PF04389.17 CCU99273.1 - 5.8e-35 120.8 0.0 8.8e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PTPLA PF04387.14 CCU99275.1 - 1.8e-49 167.7 8.0 1.8e-49 167.7 8.0 2.1 2 0 0 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA Glyco_transf_22 PF03901.17 CCU99276.1 - 2.2e-28 99.6 3.0 3.2e-28 99.1 3.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SNF2_N PF00176.23 CCU99277.1 - 2.9e-72 243.3 0.0 3.9e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 CCU99277.1 - 5e-17 61.6 0.0 9.5e-17 60.7 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 CCU99277.1 - 1.9e-14 54.0 0.0 4.4e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU99277.1 - 1.6e-09 38.0 0.0 2.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCU99277.1 - 1.1e-06 28.5 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.6 CCU99277.1 - 0.00015 21.6 13.2 0.00027 20.7 13.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCU99277.1 - 0.0026 18.1 15.3 0.0051 17.1 15.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CCU99277.1 - 0.051 13.5 15.3 0.096 12.6 15.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCU99277.1 - 0.27 11.2 15.1 0.55 10.2 15.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CCU99277.1 - 3.3 7.6 16.5 8.8 6.3 16.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ANAPC10 PF03256.16 CCU99278.1 - 2e-40 138.4 0.0 2.9e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DUF3701 PF12482.8 CCU99278.1 - 0.068 13.3 0.2 0.24 11.5 0.2 1.8 2 0 0 2 2 2 0 Phage integrase protein NIF PF03031.18 CCU99279.1 - 5.9e-25 87.8 0.0 1.8e-24 86.3 0.0 1.7 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF5302 PF17227.2 CCU99279.1 - 0.032 15.2 0.5 0.064 14.3 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5302) WD40 PF00400.32 CCU99281.1 - 6.7e-17 61.6 2.5 0.0078 17.0 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU99281.1 - 4.6e-05 23.6 0.4 13 6.2 0.0 5.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CCU99281.1 - 0.093 12.7 0.1 15 5.7 0.1 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 CCU99281.1 - 0.16 11.0 0.0 0.4 9.7 0.0 1.7 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain GalP_UDP_transf PF01087.22 CCU99282.1 - 3.7e-62 210.0 0.1 5.1e-62 209.6 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 CCU99282.1 - 1.4e-46 158.3 0.1 3.4e-46 157.0 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 CCU99282.1 - 0.0089 14.9 0.1 0.16 10.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4921) dCMP_cyt_deam_1 PF00383.23 CCU99283.1 - 1.5e-23 82.6 1.8 2.5e-23 81.9 1.8 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCU99283.1 - 1.1e-07 31.6 0.0 3e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 CCU99283.1 - 0.011 16.3 0.0 0.028 15.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 CCU99283.1 - 0.075 13.2 0.2 0.32 11.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain JmjC PF02373.22 CCU99285.1 - 5.1e-41 139.7 0.1 8.3e-41 139.0 0.1 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 CCU99285.1 - 1.2e-14 54.0 0.1 2.3e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 CCU99285.1 - 0.0083 16.4 0.1 0.029 14.6 0.1 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CCU99285.1 - 0.046 13.9 0.7 0.089 13.0 0.1 1.8 2 0 0 2 2 2 0 PHD-zinc-finger like domain TPT PF03151.16 CCU99286.1 - 2.6e-15 56.6 13.8 3.1e-15 56.3 13.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Mito_carr PF00153.27 CCU99287.1 - 3.5e-49 164.7 2.0 5.3e-15 55.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 CCU99287.1 - 0.045 14.0 0.0 12 6.1 0.0 2.9 3 1 1 4 4 4 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Ras PF00071.22 CCU99288.1 - 7.1e-64 214.3 0.7 9.1e-64 213.9 0.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCU99288.1 - 1.3e-36 125.4 0.1 2.5e-36 124.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU99288.1 - 3.1e-17 62.6 0.1 4.3e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CCU99288.1 - 1.3e-08 34.9 0.8 0.00017 21.5 0.2 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CCU99288.1 - 5.4e-06 26.1 0.2 1.8e-05 24.4 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CCU99288.1 - 4.5e-05 22.9 0.0 5.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CCU99288.1 - 4.7e-05 22.9 0.1 6e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CCU99288.1 - 6.8e-05 22.9 0.0 6.8e-05 22.9 0.0 1.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCU99288.1 - 0.00012 21.6 0.1 0.0008 19.0 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.6 CCU99288.1 - 0.0027 17.4 0.1 0.16 11.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 CCU99288.1 - 0.0054 17.2 0.1 0.61 10.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCU99288.1 - 0.011 16.1 1.0 0.012 16.0 0.0 1.8 2 1 0 2 2 1 0 AAA ATPase domain ABC_tran PF00005.27 CCU99288.1 - 0.013 16.0 0.6 0.13 12.8 0.6 2.2 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 CCU99288.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 CCU99288.1 - 0.032 13.6 0.0 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Septin PF00735.18 CCU99288.1 - 0.048 12.9 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 CCU99288.1 - 0.064 13.5 0.0 0.064 13.5 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CCU99288.1 - 0.085 12.4 2.3 1.7 8.2 0.0 2.9 2 2 1 3 3 3 0 AAA domain PduV-EutP PF10662.9 CCU99288.1 - 0.086 12.6 0.1 1.5 8.5 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CCU99288.1 - 0.094 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CCU99288.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Sec7 PF01369.20 CCU99289.1 - 2.2e-65 219.8 0.0 3.4e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CCU99289.1 - 8.7e-18 64.7 0.2 2.2e-17 63.4 0.2 1.7 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Phage_tail_APC PF16778.5 CCU99289.1 - 0.045 13.6 1.2 1.1 9.1 0.0 3.4 3 0 0 3 3 3 0 Phage tail assembly chaperone protein Med31 PF05669.12 CCU99290.1 - 2.8e-30 104.1 1.7 4.1e-30 103.6 1.7 1.2 1 0 0 1 1 1 1 SOH1 IF3_N PF05198.16 CCU99290.1 - 2.5e-07 30.9 0.1 5.8e-07 29.7 0.1 1.6 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 CCU99290.1 - 0.00049 19.8 0.0 0.0031 17.2 0.0 1.9 1 1 1 2 2 2 1 Mitochondrial translation initiation factor IF3_C PF00707.22 CCU99290.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain AAR2 PF05282.11 CCU99291.1 - 2.2e-55 188.5 0.0 3.4e-55 187.9 0.0 1.3 1 1 0 1 1 1 1 AAR2 protein Ribosomal_L2_C PF03947.18 CCU99292.1 - 1.8e-45 154.2 2.6 3e-45 153.5 2.6 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CCU99292.1 - 2.2e-13 49.9 0.1 5.4e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain EXS PF03124.14 CCU99293.1 - 5.7e-79 265.8 11.6 6.9e-79 265.6 11.6 1.1 1 0 0 1 1 1 1 EXS family DEAD PF00270.29 CCU99295.1 - 3.2e-39 134.5 0.0 4.7e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 CCU99295.1 - 7.3e-17 61.3 1.3 1.3e-16 60.6 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 CCU99295.1 - 1.1e-16 61.1 0.0 2.4e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU99295.1 - 1.7e-06 28.2 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCU99295.1 - 0.018 15.3 0.0 0.082 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain La PF05383.17 CCU99296.1 - 5.3e-23 80.8 0.0 1.2e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CCU99296.1 - 1e-06 28.4 0.4 2.8e-06 27.1 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CCU99296.1 - 0.00081 19.4 0.0 0.0087 16.1 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Dabb PF07876.12 CCU99296.1 - 0.063 13.9 0.1 0.16 12.6 0.1 1.6 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain VTC PF09359.10 CCU99297.1 - 8.2e-102 340.3 0.1 2.2e-101 338.9 0.1 1.7 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 CCU99297.1 - 1.4e-22 81.2 26.6 3.6e-08 33.7 0.5 4.5 2 1 2 4 4 4 4 SPX domain DUF202 PF02656.15 CCU99297.1 - 1.4e-11 44.7 4.7 1.4e-11 44.7 4.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Herpes_UL25 PF01499.16 CCU99297.1 - 0.024 13.2 1.8 0.039 12.5 1.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF1319 PF07028.11 CCU99297.1 - 0.081 13.2 0.0 0.31 11.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) GCIP PF13324.6 CCU99297.1 - 0.084 12.5 4.0 0.23 11.0 0.1 2.4 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting COX15-CtaA PF02628.15 CCU99298.1 - 6.1e-97 324.6 0.4 9.7e-97 323.9 0.4 1.3 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein DUF2116 PF09889.9 CCU99298.1 - 0.0024 17.8 0.0 0.0059 16.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) ATP19 PF11022.8 CCU99298.1 - 0.37 11.2 0.1 0.37 11.2 0.1 3.2 3 0 0 3 3 3 0 ATP synthase subunit K HLH PF00010.26 CCU99299.1 - 2.7e-13 49.6 0.0 5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA PF00004.29 CCU99300.1 - 2e-07 31.5 0.0 3.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCU99300.1 - 0.00022 21.7 0.2 0.00079 19.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCU99300.1 - 0.0018 18.5 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CCU99300.1 - 0.072 13.0 0.0 0.35 10.8 0.0 2.2 2 1 0 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 CCU99300.1 - 0.09 12.8 0.0 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CCU99300.1 - 0.15 11.3 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain T2SSE PF00437.20 CCU99300.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.6 CCU99300.1 - 0.3 11.5 0.4 0.54 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CCU99300.1 - 1.5 9.0 5.7 3.3 7.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain DSPn PF14671.6 CCU99302.1 - 7.8e-36 123.6 0.0 2.9e-34 118.5 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CCU99302.1 - 5.6e-12 45.6 0.0 9.7e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCU99302.1 - 0.00031 20.4 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CCU99302.1 - 0.051 13.7 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CCU99302.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family EMG1 PF03587.14 CCU99303.1 - 2.6e-77 258.9 0.0 3.3e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Ank_4 PF13637.6 CCU99304.1 - 3.8e-19 68.8 0.9 1.3e-11 44.7 0.2 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCU99304.1 - 1.1e-18 67.5 0.0 1.5e-09 38.3 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 CCU99304.1 - 1.8e-16 59.7 0.0 4e-05 23.9 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CCU99304.1 - 6.9e-15 54.9 0.9 3.4e-06 27.2 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCU99304.1 - 1.3e-13 49.7 0.3 0.00077 19.7 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeat KilA-N PF04383.13 CCU99304.1 - 1.4e-05 24.9 0.1 7e-05 22.7 0.1 1.9 1 1 0 1 1 1 1 KilA-N domain UPF0300 PF08594.10 CCU99304.1 - 0.14 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) DUF1180 PF06679.12 CCU99304.1 - 0.33 11.3 3.0 8.7 6.7 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) CLP1_P PF16575.5 CCU99305.1 - 6.5e-27 94.5 0.0 1.2e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop FtsK_SpoIIIE PF01580.18 CCU99305.1 - 0.0069 15.8 0.0 0.016 14.6 0.0 1.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Mito_carr PF00153.27 CCU99306.1 - 2e-49 165.4 1.6 3.8e-23 81.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PMT PF02366.18 CCU99307.1 - 1.1e-79 267.5 16.0 2.3e-79 266.5 16.0 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCU99307.1 - 2.3e-58 197.1 11.8 2.3e-58 197.1 11.8 2.1 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCU99307.1 - 1.1e-31 110.2 0.5 5.3e-31 107.9 0.2 2.2 2 1 0 2 2 2 1 MIR domain 5-FTHF_cyc-lig PF01812.20 CCU99308.1 - 6.9e-43 146.7 0.0 8e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Pox_C4_C10 PF03336.13 CCU99308.1 - 0.0037 16.4 0.0 0.0048 16.1 0.0 1.1 1 0 0 1 1 1 1 Poxvirus C4/C10 protein ACBP PF00887.19 CCU99309.1 - 3.2e-24 85.0 0.0 5.8e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein HlyE PF06109.13 CCU99309.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Haemolysin E (HlyE) Trimer_CC PF08954.11 CCU99309.1 - 4.3 7.0 5.5 1.4 8.6 0.5 2.5 2 0 0 2 2 2 0 Trimerisation motif Peroxin-3 PF04882.12 CCU99310.1 - 7.3e-123 411.0 0.0 8.3e-123 410.8 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 ABC_tran PF00005.27 CCU99311.1 - 2.4e-46 157.6 0.0 4.2e-26 92.1 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CCU99311.1 - 1.5e-17 64.4 0.0 0.012 15.4 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCU99311.1 - 8.3e-11 41.7 0.0 0.00015 21.3 0.0 3.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 CCU99311.1 - 1.5e-09 37.6 0.1 3.1e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 CCU99311.1 - 1.5e-07 32.1 0.1 0.015 15.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CCU99311.1 - 3.7e-06 26.6 0.2 0.059 13.1 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CCU99311.1 - 6.9e-06 26.1 0.2 0.0061 16.6 0.1 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CCU99311.1 - 0.00025 21.3 1.0 0.89 9.8 0.0 4.0 4 1 0 4 4 3 1 AAA domain DUF87 PF01935.17 CCU99311.1 - 0.00037 20.7 0.0 0.16 12.0 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 CCU99311.1 - 0.0004 20.8 1.1 0.33 11.3 0.0 4.1 3 1 1 4 4 4 1 AAA ATPase domain AAA_30 PF13604.6 CCU99311.1 - 0.001 18.8 0.1 0.27 10.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain MeaB PF03308.16 CCU99311.1 - 0.0019 17.2 1.8 0.17 10.8 0.1 2.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Tudor-knot PF11717.8 CCU99311.1 - 0.0021 17.9 0.2 0.0054 16.6 0.2 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain RsgA_GTPase PF03193.16 CCU99311.1 - 0.0036 17.2 0.1 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 CCU99311.1 - 0.0053 16.1 0.1 10 5.3 0.0 4.2 4 0 0 4 4 4 0 Zeta toxin NACHT PF05729.12 CCU99311.1 - 0.011 15.6 0.0 5.5 6.9 0.0 3.1 4 0 0 4 4 3 0 NACHT domain AAA_15 PF13175.6 CCU99311.1 - 0.011 15.4 0.0 0.85 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain HEAT_EZ PF13513.6 CCU99311.1 - 0.013 16.0 6.5 22 5.7 0.1 5.3 5 0 0 5 5 4 0 HEAT-like repeat AAA_28 PF13521.6 CCU99311.1 - 0.017 15.4 0.0 6.6 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 CCU99311.1 - 0.036 13.6 0.4 6.5 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CCU99311.1 - 0.044 13.5 0.0 5.1 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CCU99311.1 - 0.045 14.3 0.0 3.6 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CCU99311.1 - 0.053 13.7 0.1 1.9 8.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 CCU99311.1 - 0.089 13.2 0.0 2.1 8.8 0.0 2.9 3 0 0 3 3 2 0 RNA helicase cobW PF02492.19 CCU99311.1 - 0.1 12.1 0.2 6.8 6.2 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 CCU99311.1 - 0.11 12.6 0.0 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AAA_7 PF12775.7 CCU99311.1 - 0.23 11.0 0.5 0.7 9.4 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region MMS19_C PF12460.8 CCU99311.1 - 0.28 10.3 1.3 25 3.8 0.1 2.9 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal HEAT PF02985.22 CCU99311.1 - 1.3 9.4 3.6 9.9 6.7 0.0 4.2 5 0 0 5 5 3 0 HEAT repeat ABC_tran_Xtn PF12848.7 CCU99311.1 - 6.5 6.9 9.0 0.097 12.7 0.6 2.3 2 0 0 2 2 1 0 ABC transporter WD40 PF00400.32 CCU99312.1 - 2.5e-07 31.3 0.1 0.0078 17.0 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat DnaJ PF00226.31 CCU99313.1 - 3.4e-16 59.1 0.2 8.3e-16 57.9 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 CCU99313.1 - 3.7e-05 23.0 0.0 0.21 10.7 0.0 2.1 2 0 0 2 2 2 2 Sec63 Brl domain NOA36 PF06524.12 CCU99313.1 - 0.031 13.6 9.3 0.044 13.1 9.3 1.2 1 0 0 1 1 1 0 NOA36 protein Fumble PF03630.14 CCU99314.1 - 1.5e-124 415.5 0.0 2.5e-124 414.8 0.0 1.4 1 0 0 1 1 1 1 Fumble Spt4 PF06093.13 CCU99315.1 - 3.2e-25 88.0 0.3 3.8e-25 87.8 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Glyco_transf_15 PF01793.16 CCU99317.1 - 4.4e-103 344.9 7.8 5.6e-103 344.6 7.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase TK PF00265.18 CCU99317.1 - 0.19 11.6 0.4 0.49 10.2 0.2 1.6 2 0 0 2 2 2 0 Thymidine kinase RNA_pol_A_bac PF01000.26 CCU99318.1 - 1e-18 67.7 0.0 1e-17 64.5 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CCU99318.1 - 9.5e-05 21.8 0.0 0.00013 21.3 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain BORA_N PF15280.6 CCU99318.1 - 0.23 11.1 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein aurora borealis N-terminus URO-D PF01208.17 CCU99319.1 - 2.1e-127 425.1 0.0 2.4e-127 424.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) TIP49 PF06068.13 CCU99320.1 - 2.4e-159 530.2 0.0 3.1e-159 529.9 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CCU99320.1 - 1.5e-21 76.3 0.1 4.4e-21 74.8 0.1 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CCU99320.1 - 5.2e-10 39.9 1.3 2.2e-05 24.9 0.1 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCU99320.1 - 2.9e-09 36.9 0.0 8.7e-06 25.6 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCU99320.1 - 1.2e-07 32.1 0.2 0.016 15.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 CCU99320.1 - 0.00017 22.0 1.7 0.12 12.7 0.1 3.0 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 CCU99320.1 - 0.00022 21.2 0.1 0.1 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CCU99320.1 - 0.00072 19.2 0.9 0.0032 17.1 0.3 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CCU99320.1 - 0.0012 19.2 1.2 0.036 14.5 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 CCU99320.1 - 0.0049 17.1 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CCU99320.1 - 0.0086 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 CCU99320.1 - 0.013 15.2 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 CCU99320.1 - 0.018 14.5 0.1 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CCU99320.1 - 0.038 13.7 0.1 0.11 12.2 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 CCU99320.1 - 0.057 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 CCU99320.1 - 0.059 12.6 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 CCU99320.1 - 0.093 12.0 0.1 0.25 10.6 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin IMPDH PF00478.25 CCU99321.1 - 5.4e-133 443.3 0.1 2e-131 438.1 0.1 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CCU99321.1 - 7.5e-17 61.5 0.4 5.4e-08 33.2 0.0 3.0 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 CCU99321.1 - 6.9e-12 45.4 0.7 5.2e-10 39.2 0.2 2.3 2 0 0 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.18 CCU99321.1 - 7e-12 45.0 0.6 3.9e-11 42.6 0.3 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CCU99321.1 - 1.5e-07 31.1 1.5 1.9e-06 27.5 1.5 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.14 CCU99321.1 - 0.00017 20.8 0.1 0.00033 19.9 0.1 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.14 CCU99321.1 - 0.0009 18.6 2.6 0.0017 17.7 1.0 2.0 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG RHH_5 PF07878.11 CCU99321.1 - 0.0013 18.6 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 G3P_antiterm PF04309.12 CCU99321.1 - 0.015 14.7 0.3 1.2 8.5 0.1 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Aldolase PF01081.19 CCU99321.1 - 0.017 14.5 0.2 0.054 12.9 0.1 1.9 2 0 0 2 2 2 0 KDPG and KHG aldolase Glu_synthase PF01645.17 CCU99321.1 - 0.027 13.6 2.1 0.047 12.8 2.1 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase EAL PF00563.20 CCU99321.1 - 0.053 13.0 0.7 9.8 5.6 0.1 2.5 2 1 0 2 2 2 0 EAL domain Dus PF01207.17 CCU99321.1 - 0.085 11.9 0.9 0.6 9.2 0.2 2.1 1 1 0 2 2 2 0 Dihydrouridine synthase (Dus) TruB_C PF09142.11 CCU99321.1 - 0.1 12.4 0.3 0.78 9.6 0.0 2.4 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal PcrB PF01884.17 CCU99321.1 - 0.44 10.0 2.0 48 3.3 0.0 3.7 3 1 2 5 5 5 0 PcrB family TAF4 PF05236.14 CCU99322.1 - 7.3e-31 107.9 2.1 7.3e-31 107.9 2.1 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family PPR_2 PF13041.6 CCU99323.1 - 2.6e-34 117.1 0.1 1.2e-11 44.6 0.0 9.9 9 3 4 13 13 13 4 PPR repeat family PPR PF01535.20 CCU99323.1 - 3e-24 83.5 4.5 0.00015 21.8 0.0 12.4 12 2 0 12 12 12 5 PPR repeat PPR_3 PF13812.6 CCU99323.1 - 6.7e-22 77.3 0.1 6.4e-08 32.6 0.0 6.6 4 1 2 6 6 6 5 Pentatricopeptide repeat domain PPR_long PF17177.4 CCU99323.1 - 1.6e-16 60.3 6.1 6.5e-14 51.8 0.2 3.6 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CCU99323.1 - 4.1e-16 58.4 0.0 1.7e-06 27.6 0.0 7.9 9 0 0 9 9 9 3 PPR repeat TPR_19 PF14559.6 CCU99323.1 - 0.0025 18.3 0.8 11 6.6 0.0 5.5 4 1 0 4 4 4 1 Tetratricopeptide repeat RPM2 PF08579.11 CCU99323.1 - 0.011 16.2 0.0 0.41 11.1 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.11 CCU99323.1 - 0.11 11.6 0.3 13 4.8 0.1 2.8 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway ERAP1_C PF11838.8 CCU99323.1 - 0.17 11.4 5.5 6.8 6.1 0.2 3.7 3 1 0 3 3 3 0 ERAP1-like C-terminal domain TPR_6 PF13174.6 CCU99323.1 - 0.39 11.5 1.8 1.2e+02 3.7 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.22 CCU99324.1 - 4e-20 71.4 0.0 2.7e-08 33.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 CCU99325.1 - 4.7e-86 288.7 0.0 7e-86 288.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CCU99325.1 - 1.1e-14 54.6 0.0 2.2e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 Microtubule binding UPF0449 PF15136.6 CCU99325.1 - 0.042 14.3 0.7 0.31 11.5 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 VirE_N PF08800.10 CCU99325.1 - 0.089 12.9 0.3 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 VirE N-terminal domain CENP-Q PF13094.6 CCU99325.1 - 0.17 12.1 4.4 0.33 11.1 4.4 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Peptidase_M24 PF00557.24 CCU99326.1 - 2.2e-53 181.1 0.1 3.2e-53 180.5 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CCU99326.1 - 2.6e-18 65.9 0.1 2.3e-12 46.7 0.1 2.4 2 0 0 2 2 2 2 Aminopeptidase P, N-terminal domain S4 PF01479.25 CCU99327.1 - 3e-11 42.8 0.0 6.5e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 CCU99327.1 - 5.7e-11 43.2 0.4 8.6e-11 42.6 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Fe_hyd_lg_C PF02906.14 CCU99328.1 - 3.6e-59 200.4 0.0 5.8e-59 199.7 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SNARE PF05739.19 CCU99329.1 - 2.6e-08 33.7 6.1 4.5e-08 33.0 0.3 3.0 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 CCU99329.1 - 1.4e-07 31.4 11.3 2.7e-07 30.5 1.6 2.2 2 0 0 2 2 2 2 Syntaxin MCPsignal PF00015.21 CCU99329.1 - 0.0039 17.0 4.4 0.0083 16.0 0.2 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 CCU99329.1 - 0.048 13.9 0.4 0.048 13.9 0.4 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Synaptobrevin PF00957.21 CCU99329.1 - 2.5 7.9 7.3 0.17 11.7 0.5 2.5 3 0 0 3 3 3 0 Synaptobrevin Syntaxin_2 PF14523.6 CCU99329.1 - 3.8 7.9 9.5 3.8 7.9 2.6 2.5 2 1 0 2 2 2 0 Syntaxin-like protein APG6_N PF17675.1 CCU99329.1 - 4.2 7.9 14.2 6.4 7.3 1.1 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 CCU99329.1 - 4.2 6.5 6.7 2.6 7.2 1.8 2.0 1 1 1 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.10 CCU99329.1 - 4.7 7.4 9.7 2.1 8.5 2.4 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 CCU99329.1 - 8.5 7.1 13.5 0.16 12.6 1.2 3.2 3 2 1 4 4 4 0 SlyX NDUF_B7 PF05676.13 CCU99330.1 - 6.8e-19 67.4 3.8 3.2e-18 65.2 3.8 1.9 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) XRN_M PF17846.1 CCU99331.1 - 9e-152 506.1 4.6 3.3e-111 372.4 0.1 2.4 2 1 1 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 CCU99331.1 - 2.1e-92 308.9 0.0 5.2e-92 307.6 0.0 1.7 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 CCU99331.1 - 0.0004 20.3 6.2 0.00068 19.6 6.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CCU99331.1 - 0.02 14.9 1.3 0.042 13.8 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 CCU99331.1 - 0.22 11.4 4.3 0.55 10.1 4.3 1.6 1 0 0 1 1 1 0 Zinc knuckle PMI_typeI PF01238.21 CCU99332.1 - 1.7e-113 379.6 0.0 1.9e-113 379.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 CCU99332.1 - 0.016 14.9 0.0 4.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Cupin domain AraC_binding PF02311.19 CCU99332.1 - 0.043 13.7 0.0 18 5.2 0.0 2.7 3 0 0 3 3 3 0 AraC-like ligand binding domain DIE2_ALG10 PF04922.12 CCU99333.1 - 4.5e-43 148.0 8.9 6.9e-43 147.4 8.9 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family Abhydrolase_3 PF07859.13 CCU99334.1 - 1.5e-57 194.8 0.0 1.1e-27 97.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CCU99334.1 - 8.2e-11 41.8 0.1 0.00065 19.2 0.0 3.6 3 1 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 CCU99334.1 - 7.2e-08 32.2 0.1 0.002 17.7 0.0 2.9 3 0 0 3 3 3 2 Dienelactone hydrolase family AXE1 PF05448.12 CCU99334.1 - 1.9e-06 26.8 0.0 0.034 12.8 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 CCU99334.1 - 0.00013 21.9 0.0 0.52 10.2 0.0 2.4 2 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.9 CCU99334.1 - 0.0014 18.2 0.1 2 7.9 0.0 2.7 3 0 0 3 3 3 2 Esterase PHB depolymerase DUF2974 PF11187.8 CCU99334.1 - 0.0024 17.5 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Esterase PF00756.20 CCU99334.1 - 0.015 15.0 0.0 3.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Putative esterase Say1_Mug180 PF10340.9 CCU99334.1 - 0.018 13.9 0.0 5.1 5.9 0.0 2.3 2 0 0 2 2 2 0 Steryl acetyl hydrolase Thioesterase PF00975.20 CCU99334.1 - 0.021 15.0 0.0 0.59 10.2 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_2 PF02230.16 CCU99334.1 - 0.045 13.5 0.0 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Acetyltransf_1 PF00583.25 CCU99335.1 - 0.00045 20.4 0.0 0.00052 20.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCU99335.1 - 0.013 15.9 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CwfJ_C_1 PF04677.15 CCU99336.1 - 1.5e-28 99.1 0.0 2.5e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CCU99336.1 - 4.3e-09 37.1 0.1 9.5e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Cnd1 PF12717.7 CCU99337.1 - 4.8e-54 182.8 5.8 7.9e-50 169.1 0.0 4.6 5 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 CCU99337.1 - 6.7e-36 123.6 0.0 1.4e-35 122.6 0.0 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 CCU99337.1 - 4.7e-07 30.1 5.8 0.043 14.2 0.1 5.7 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.22 CCU99337.1 - 7.1e-06 25.9 4.3 1.5 9.3 0.1 6.8 6 0 0 6 6 6 2 HEAT repeat Cnd3 PF12719.7 CCU99337.1 - 8e-06 25.3 0.5 2.7e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 CCU99337.1 - 0.00012 20.8 0.2 0.016 13.8 0.1 2.9 2 0 0 2 2 2 1 Adaptin N terminal region HEAT_EZ PF13513.6 CCU99337.1 - 0.015 15.8 9.7 0.23 12.0 0.3 5.5 5 1 1 6 6 6 0 HEAT-like repeat CLASP_N PF12348.8 CCU99337.1 - 0.025 14.2 0.0 0.58 9.7 0.0 2.9 2 0 0 2 2 2 0 CLASP N terminal RTP1_C1 PF10363.9 CCU99337.1 - 0.029 14.5 1.9 7.1 6.9 0.0 4.3 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HHH_7 PF14635.6 CCU99337.1 - 0.085 13.2 0.0 0.34 11.3 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sec62 PF03839.16 CCU99338.1 - 1.5e-50 171.7 1.0 2.3e-50 171.1 1.0 1.2 1 1 0 1 1 1 1 Translocation protein Sec62 DUF3413 PF11893.8 CCU99338.1 - 1.7 7.8 7.4 2.4 7.2 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) DUF4672 PF15716.5 CCU99338.1 - 3.3 7.3 4.4 5.9 6.5 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) Alg6_Alg8 PF03155.15 CCU99339.1 - 3.2e-119 399.1 9.9 1.5e-118 396.8 9.9 1.9 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Actin PF00022.19 CCU99340.1 - 2.1e-115 385.6 0.0 7.9e-115 383.7 0.0 1.7 1 1 0 1 1 1 1 Actin UCH PF00443.29 CCU99341.1 - 2.2e-53 181.4 0.1 2.9e-53 181.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCU99341.1 - 5.2e-31 108.4 1.1 1.4e-30 107.0 1.1 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CCU99341.1 - 0.017 14.6 1.0 0.068 12.6 1.0 1.9 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DPBB_1 PF03330.18 CCU99342.1 - 1.6e-07 31.5 0.1 2.7e-07 30.7 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CCU99342.1 - 9.6e-05 22.2 0.3 0.00016 21.5 0.3 1.4 1 0 0 1 1 1 1 Barwin family Phage_Gp23 PF10669.9 CCU99342.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Yippee-Mis18 PF03226.14 CCU99343.1 - 1.2e-11 44.7 0.9 1.5e-11 44.4 0.9 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.9 CCU99343.1 - 0.02 15.3 3.5 0.058 13.7 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) AlcCBM31 PF11606.8 CCU99343.1 - 0.067 13.4 0.2 0.5 10.6 0.1 2.0 1 1 1 2 2 2 0 Family 31 carbohydrate binding protein RIG-I_C-RD PF11648.8 CCU99343.1 - 0.17 12.1 4.5 0.29 11.4 4.5 1.4 1 1 0 1 1 1 0 C-terminal domain of RIG-I TIM21 PF08294.11 CCU99344.1 - 1.2e-07 31.7 0.0 0.00011 22.1 0.0 2.5 2 1 0 2 2 2 2 TIM21 Thoc2 PF11732.8 CCU99344.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Transcription- and export-related complex subunit RL10P_insert PF17777.1 CCU99345.1 - 2.4e-23 81.9 0.1 3.7e-23 81.3 0.1 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CCU99345.1 - 2.9e-18 65.9 0.0 4.6e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 HEAT_2 PF13646.6 CCU99346.1 - 1.4e-27 95.9 3.9 9.9e-13 48.3 0.2 3.3 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 CCU99346.1 - 1.1e-13 50.5 8.1 0.0017 18.9 0.1 7.3 8 0 0 8 8 8 3 PBS lyase HEAT-like repeat HEAT PF02985.22 CCU99346.1 - 6.6e-10 38.4 4.3 1.1 9.6 0.0 6.9 6 1 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 CCU99346.1 - 9.1e-07 29.3 2.7 0.11 13.0 0.2 4.8 4 1 1 5 5 5 2 HEAT-like repeat IFRD PF05004.13 CCU99346.1 - 0.0028 16.8 0.1 0.056 12.5 0.0 2.7 3 0 0 3 3 3 1 Interferon-related developmental regulator (IFRD) Arm PF00514.23 CCU99346.1 - 0.0084 16.1 0.3 14 5.9 0.0 3.8 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat UPF0147 PF03685.13 CCU99346.1 - 0.0093 16.0 0.2 3.8 7.6 0.0 3.3 2 2 2 4 4 4 2 Uncharacterised protein family (UPF0147) TAF6_C PF07571.13 CCU99346.1 - 0.12 12.7 0.0 5.9 7.3 0.0 2.9 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain CoA_binding PF02629.19 CCU99347.1 - 2.6e-28 98.5 1.4 4e-28 97.9 0.4 1.8 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CCU99347.1 - 6.3e-21 74.8 0.0 1.1e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CCU99347.1 - 1.6e-06 27.9 0.0 3.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CCU99347.1 - 0.00014 22.3 0.1 0.00041 20.8 0.1 1.8 2 0 0 2 2 2 1 CoA binding domain DUF3562 PF12085.8 CCU99347.1 - 0.04 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) GFO_IDH_MocA PF01408.22 CCU99347.1 - 0.04 14.7 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Vta1 PF04652.16 CCU99348.1 - 2.6e-24 85.9 0.0 3.8e-12 46.4 0.0 2.5 1 1 1 2 2 2 2 Vta1 like Vta1_C PF18097.1 CCU99348.1 - 1.5e-15 56.6 0.4 1.5e-15 56.6 0.4 2.1 2 0 0 2 2 2 1 Vta1 C-terminal domain DWNN PF08783.11 CCU99349.1 - 5e-31 106.8 0.0 8.8e-31 106.0 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 CCU99349.1 - 7.6e-10 38.4 6.2 1.5e-09 37.5 6.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CCU99349.1 - 2.3e-06 27.4 1.4 4.1e-06 26.6 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 CCU99349.1 - 0.00011 22.0 12.8 0.00011 22.0 12.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.6 CCU99349.1 - 0.0017 18.3 0.2 0.0048 16.8 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_3 PF13920.6 CCU99349.1 - 0.011 15.5 9.2 0.011 15.5 9.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCU99349.1 - 0.043 13.7 13.3 0.084 12.8 13.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf_C2H2_10 PF18414.1 CCU99349.1 - 0.045 13.3 0.5 0.045 13.3 0.5 2.7 3 0 0 3 3 3 0 C2H2 type zinc-finger zf_UBZ PF18439.1 CCU99349.1 - 0.15 11.7 0.2 0.15 11.7 0.2 3.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-RING_5 PF14634.6 CCU99349.1 - 0.19 11.7 18.6 0.039 13.9 12.7 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CCU99349.1 - 0.25 11.5 14.4 0.55 10.4 14.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CCU99349.1 - 0.73 9.7 7.2 0.16 11.9 3.4 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Gin PF10764.9 CCU99349.1 - 0.95 9.5 6.7 0.98 9.4 2.3 2.5 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin zf-RING_2 PF13639.6 CCU99349.1 - 3.5 8.0 19.0 0.052 13.9 11.9 1.7 2 0 0 2 2 2 0 Ring finger domain Methyltransf_16 PF10294.9 CCU99350.1 - 8.3e-20 71.2 0.0 1.2e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Sec8_exocyst PF04048.14 CCU99351.1 - 1.1e-18 67.5 0.0 2.2e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Ribosomal_S5 PF00333.20 CCU99352.1 - 4.9e-18 64.9 2.2 1.2e-17 63.6 2.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CCU99352.1 - 2.1e-17 62.3 0.1 6.9e-17 60.7 0.1 1.9 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain RRM_1 PF00076.22 CCU99353.1 - 1.3e-32 111.4 0.0 2.7e-18 65.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.9 CCU99354.1 - 5.5e-18 65.3 0.0 6.6e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CCU99354.1 - 0.00024 20.6 0.0 0.00031 20.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 CCU99354.1 - 0.0011 18.8 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCU99354.1 - 0.0028 18.3 0.0 0.0044 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain bZIP_1 PF00170.21 CCU99355.1 - 1.3e-08 34.7 11.5 7.9e-08 32.3 8.6 2.3 1 1 1 2 2 2 1 bZIP transcription factor Hap4_Hap_bind PF10297.9 CCU99355.1 - 2.4e-06 27.5 0.8 6.7e-06 26.0 0.8 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 DUF5543 PF17697.1 CCU99355.1 - 0.0048 17.2 0.1 0.014 15.6 0.1 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5543) NUDE_C PF04880.13 CCU99355.1 - 0.036 14.6 2.6 0.036 14.6 2.6 2.9 2 2 1 3 3 3 0 NUDE protein, C-terminal conserved region MbeD_MobD PF04899.12 CCU99355.1 - 0.41 10.8 8.1 0.77 9.9 7.2 2.0 1 1 1 2 2 2 0 MbeD/MobD like bZIP_2 PF07716.15 CCU99355.1 - 0.85 9.8 15.4 2.8 8.1 7.5 2.5 1 1 1 2 2 2 0 Basic region leucine zipper Prominin PF05478.11 CCU99355.1 - 2.1 6.2 6.4 2.9 5.7 6.4 1.1 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 CCU99355.1 - 5.5 6.3 7.4 8.1 5.7 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 CCU99355.1 - 7.1 7.1 9.2 2 8.9 5.5 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) His_Phos_1 PF00300.22 CCU99356.1 - 2.3e-23 82.9 0.2 2.8e-23 82.6 0.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RibD_C PF01872.17 CCU99357.1 - 7e-32 110.9 0.0 8.2e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Cyclin_N PF00134.23 CCU99358.1 - 3.3e-07 30.1 0.6 6.8e-07 29.1 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Lyase_1 PF00206.20 CCU99359.1 - 2.7e-22 79.6 0.0 4.1e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CCU99359.1 - 1.1e-18 67.5 0.0 2.7e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus SelR PF01641.18 CCU99360.1 - 1.6e-51 173.5 0.1 2e-51 173.2 0.1 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 CCU99360.1 - 0.003 17.8 0.3 0.007 16.6 0.3 1.6 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 CCU99360.1 - 0.064 13.0 0.2 0.93 9.3 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Mss51 PF13824.6 CCU99360.1 - 0.32 11.1 2.5 6.4 7.0 0.7 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DNA_RNApol_7kD PF03604.13 CCU99360.1 - 0.7 9.6 4.5 7.8 6.3 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Evr1_Alr PF04777.13 CCU99361.1 - 3.1e-28 98.2 2.2 4.2e-28 97.8 2.2 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Indigoidine_A PF04227.12 CCU99362.1 - 6.2e-56 189.9 0.0 3e-55 187.7 0.0 1.9 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.24 CCU99362.1 - 1.8e-18 66.9 0.0 8.4e-18 64.7 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Abhydrolase_1 PF00561.20 CCU99363.1 - 2e-14 53.9 0.2 4.3e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCU99363.1 - 2.1e-14 54.7 0.6 2.8e-14 54.3 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCU99363.1 - 1.1e-11 44.5 0.3 2.1e-11 43.6 0.3 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CCU99363.1 - 4.9e-05 23.6 0.0 9.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 CCU99363.1 - 0.0032 17.1 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 CCU99363.1 - 0.0034 17.3 0.4 0.073 12.9 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 CCU99363.1 - 0.023 14.4 0.1 0.13 12.0 0.1 1.9 2 0 0 2 2 2 0 PGAP1-like protein DLH PF01738.18 CCU99363.1 - 0.051 13.1 0.1 8.8 5.8 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 CCU99363.1 - 0.095 12.5 1.3 0.31 10.8 0.2 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Methyltransf_PK PF05891.12 CCU99364.1 - 7e-46 156.5 0.0 1.7e-20 73.5 0.0 3.3 2 2 1 3 3 3 3 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CCU99364.1 - 3.9e-06 27.5 0.0 0.095 13.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CCU99364.1 - 6.8e-05 23.4 0.0 0.015 15.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCU99364.1 - 0.001 19.8 0.0 0.0083 16.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCU99364.1 - 0.0078 16.1 0.0 0.056 13.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CitG PF01874.16 CCU99364.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase Anoctamin PF04547.12 CCU99365.1 - 1.4e-62 212.0 5.5 1.9e-62 211.6 5.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Memo PF01875.17 CCU99367.1 - 6.7e-23 81.2 0.0 7.7e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein ResIII PF04851.15 CCU99368.1 - 1.7e-20 73.7 0.0 3e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCU99368.1 - 2.2e-14 53.7 0.0 1.2e-13 51.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCU99368.1 - 1.1e-13 51.4 0.0 2e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CCU99368.1 - 2e-05 24.4 0.0 3.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 CCU99368.1 - 7e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CCU99368.1 - 0.00048 20.5 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCU99368.1 - 0.0031 17.2 0.1 0.0075 16.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CCU99368.1 - 0.0039 16.8 0.0 0.097 12.2 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CCU99368.1 - 0.01 16.1 0.1 0.039 14.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CCU99368.1 - 0.04 13.7 0.0 5.2 6.8 0.0 2.2 1 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 CCU99368.1 - 0.062 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 CCU99368.1 - 0.11 12.8 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CCU99368.1 - 0.13 12.6 0.0 0.32 11.4 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cys_Met_Meta_PP PF01053.20 CCU99370.1 - 1.4e-43 148.9 0.0 1.8e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CCU99370.1 - 0.0036 16.3 0.0 0.0052 15.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CCU99370.1 - 0.019 14.1 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II ApoO PF09769.9 CCU99372.1 - 1.7e-13 50.6 0.5 1.2e-12 47.9 0.1 2.3 2 1 0 3 3 3 1 Apolipoprotein O PCI PF01399.27 CCU99373.1 - 7.1e-06 26.5 0.1 1.7e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 PCI domain TatD_DNase PF01026.21 CCU99374.1 - 3.8e-36 124.8 0.0 5.1e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF3591 PF12157.8 CCU99375.1 - 1.8e-180 600.3 0.1 1.8e-180 600.3 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 CCU99375.1 - 5.8e-06 26.1 1.7 1.2e-05 25.0 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle PQ-loop PF04193.14 CCU99376.1 - 0.039 13.7 0.3 0.14 12.0 0.3 1.9 1 0 0 1 1 1 0 PQ loop repeat ApbA_C PF08546.11 CCU99377.1 - 6.4e-37 126.5 0.0 1.1e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CCU99377.1 - 5.9e-22 77.9 0.0 8.7e-18 64.4 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA CoA_binding_2 PF13380.6 CCU99377.1 - 0.11 13.1 0.1 0.28 11.7 0.1 1.7 1 0 0 1 1 1 0 CoA binding domain SMC_N PF02463.19 CCU99378.1 - 6.2e-25 87.9 0.0 9.1e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCU99378.1 - 9.8e-15 55.6 12.7 9.8e-15 55.6 12.7 4.6 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 CCU99378.1 - 2e-09 37.6 0.1 1.5e-08 34.8 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CCU99378.1 - 2.1e-05 24.1 0.0 5.8e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CCU99378.1 - 2.6e-05 24.2 1.2 0.0032 17.3 1.0 2.7 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 CCU99378.1 - 0.03 14.8 0.0 0.03 14.8 0.0 4.9 3 2 0 3 3 3 0 ABC transporter UvrA_DNA-bind PF17755.1 CCU99378.1 - 0.092 13.1 0.0 0.3 11.4 0.0 1.9 1 0 0 1 1 1 0 UvrA DNA-binding domain Hydrolase_4 PF12146.8 CCU99379.1 - 1e-21 77.3 0.8 2.6e-12 46.6 0.0 2.4 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCU99379.1 - 2.1e-14 53.8 0.2 2.2e-09 37.3 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCU99379.1 - 1.1e-07 32.7 2.6 8.6e-07 29.8 2.2 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 CCU99379.1 - 6.2e-07 28.4 0.1 0.0014 17.4 0.0 2.7 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 CCU99379.1 - 2.8e-06 27.1 0.0 0.00018 21.2 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 CCU99379.1 - 3e-06 27.3 0.0 0.00096 19.1 0.0 2.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 CCU99379.1 - 1e-05 25.2 0.0 4.7e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 CCU99379.1 - 2.4e-05 24.3 0.2 0.14 11.9 0.0 2.6 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 CCU99379.1 - 0.00025 20.8 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 CCU99379.1 - 0.00027 20.5 0.3 0.0047 16.4 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 CCU99379.1 - 0.006 16.2 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 2 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 CCU99379.1 - 0.014 15.3 0.2 0.036 13.9 0.1 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 CCU99379.1 - 0.023 14.5 0.0 0.44 10.3 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase family Esterase PF00756.20 CCU99379.1 - 0.04 13.6 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase LIP PF03583.14 CCU99379.1 - 0.041 13.2 0.1 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase 6PF2K PF01591.18 CCU99380.1 - 6.6e-54 182.6 0.1 9e-54 182.1 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CCU99380.1 - 2.9e-22 79.3 0.1 4.4e-20 72.2 0.0 2.8 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CCU99380.1 - 3.6e-09 36.9 0.1 3.6e-09 36.9 0.1 2.1 3 0 0 3 3 3 1 AAA domain CPT PF07931.12 CCU99380.1 - 0.00038 20.4 0.0 0.00075 19.4 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 CCU99380.1 - 0.0046 16.5 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.20 CCU99380.1 - 0.018 15.0 0.1 0.05 13.5 0.1 1.7 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 CCU99380.1 - 0.037 14.4 0.1 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CCU99380.1 - 0.047 14.1 0.0 0.21 12.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CCU99380.1 - 0.053 14.1 0.1 0.15 12.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CCU99380.1 - 0.13 11.9 0.0 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein FRG1 PF06229.12 CCU99381.1 - 9.9e-11 41.7 0.0 2.6e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 CCU99381.1 - 5.4e-05 23.4 0.0 0.0028 17.9 0.0 2.3 2 0 0 2 2 2 1 Fascin domain OTCace PF00185.24 CCU99382.1 - 1.4e-44 151.9 0.0 2.2e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 CCU99382.1 - 1.8e-43 148.1 0.1 2.9e-43 147.4 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GSHPx PF00255.19 CCU99382.1 - 1.1e-37 127.9 0.2 1.9e-37 127.1 0.2 1.4 1 0 0 1 1 1 1 Glutathione peroxidase TAF PF02969.17 CCU99382.1 - 0.006 16.7 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) AhpC-TSA PF00578.21 CCU99382.1 - 0.0082 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCU99382.1 - 0.037 13.7 0.0 0.091 12.5 0.0 1.6 1 1 0 1 1 1 0 Redoxin NDK PF00334.19 CCU99383.1 - 2.7e-54 182.9 0.0 3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 CCU99383.1 - 0.019 15.5 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ ABC1 PF03109.16 CCU99384.1 - 1.5e-13 51.0 0.0 3.4e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CCU99384.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Occludin_ELL PF07303.13 CCU99385.1 - 0.037 14.8 0.8 0.12 13.2 0.1 2.0 1 1 1 2 2 2 0 Occludin homology domain LemA PF04011.12 CCU99385.1 - 0.08 12.8 1.2 0.13 12.1 1.2 1.3 1 0 0 1 1 1 0 LemA family T3SS_needle_F PF09392.10 CCU99385.1 - 0.21 11.8 0.8 2 8.7 0.6 2.5 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF ABC_membrane PF00664.23 CCU99386.1 - 1.1e-55 189.2 32.0 3.4e-30 105.6 12.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCU99386.1 - 5.6e-53 179.1 0.0 4.4e-30 105.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCU99386.1 - 2.4e-07 30.4 0.0 0.0052 16.3 0.0 3.5 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCU99386.1 - 1.8e-05 24.4 0.3 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CCU99386.1 - 0.00031 20.7 6.2 2.1 8.1 0.2 4.8 4 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CCU99386.1 - 0.0012 18.9 1.0 0.15 12.1 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CCU99386.1 - 0.0016 18.9 0.1 2.6 8.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CCU99386.1 - 0.0039 17.1 0.4 3.2 7.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 CCU99386.1 - 0.022 14.9 1.0 0.19 11.8 0.5 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 CCU99386.1 - 0.042 13.5 0.3 4.2 7.0 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CCU99386.1 - 0.088 12.3 0.1 14 5.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 CCU99386.1 - 0.11 12.9 5.4 2.5 8.5 0.2 2.9 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 CCU99386.1 - 0.16 11.5 2.1 11 5.5 0.2 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.6 CCU99386.1 - 0.21 11.4 2.4 0.69 9.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 CCU99386.1 - 0.44 10.8 3.1 11 6.3 0.2 3.4 3 0 0 3 3 3 0 AAA domain PfkB PF00294.24 CCU99387.1 - 4.6e-66 223.2 3.2 6.1e-66 222.8 3.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CCU99387.1 - 3.9e-06 26.4 0.0 9.3e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PCI PF01399.27 CCU99388.1 - 4.6e-17 62.4 0.0 1.9e-16 60.5 0.0 2.1 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 CCU99388.1 - 1.4e-13 50.7 3.4 1.4e-13 50.7 3.4 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain CorC_HlyC PF03471.17 CCU99388.1 - 0.088 12.8 0.0 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 Transporter associated domain SURF1 PF02104.15 CCU99389.1 - 5.4e-39 134.3 0.0 6.5e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Complex1_51K PF01512.17 CCU99390.1 - 1.6e-46 157.9 0.0 2.3e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CCU99390.1 - 4.1e-28 97.3 0.1 7.2e-28 96.5 0.1 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CCU99390.1 - 3.1e-08 33.3 0.0 7.9e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 SLBB domain Myf5 PF12232.8 CCU99390.1 - 0.089 13.6 0.0 0.16 12.8 0.0 1.3 1 0 0 1 1 1 0 Myogenic determination factor 5 DUF3568 PF12092.8 CCU99390.1 - 0.29 11.2 0.6 0.51 10.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) DUF1491 PF07372.12 CCU99391.1 - 0.086 13.2 0.2 0.11 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) TIP49 PF06068.13 CCU99392.1 - 2.5e-158 526.9 1.5 3.4e-158 526.4 1.5 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CCU99392.1 - 1.7e-24 85.7 1.6 8.2e-24 83.5 0.8 2.5 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 CCU99392.1 - 1.7e-09 38.2 0.5 5.4e-07 30.1 0.2 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCU99392.1 - 2.3e-08 34.0 0.2 4.4e-05 23.3 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CCU99392.1 - 4e-06 26.9 0.4 0.0021 18.1 0.1 3.2 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 CCU99392.1 - 4.3e-06 26.3 0.8 8e-06 25.4 0.8 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 CCU99392.1 - 1.2e-05 24.8 2.7 0.00017 21.1 0.9 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CCU99392.1 - 0.00026 21.3 3.8 0.0008 19.8 1.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCU99392.1 - 0.00028 21.3 0.1 0.0013 19.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCU99392.1 - 0.00035 20.9 0.0 0.55 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CCU99392.1 - 0.00038 20.2 0.2 0.26 11.0 0.1 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.6 CCU99392.1 - 0.00042 20.7 0.7 0.0019 18.6 0.5 2.3 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 CCU99392.1 - 0.0021 17.7 0.1 0.0063 16.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCU99392.1 - 0.0028 17.8 0.0 0.0082 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CCU99392.1 - 0.0094 15.8 1.4 0.037 13.8 1.4 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCU99392.1 - 0.011 15.2 2.3 0.014 14.9 0.1 2.2 3 0 0 3 3 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 CCU99392.1 - 0.022 14.5 0.5 0.3 10.8 0.4 2.4 2 0 0 2 2 2 0 AAA domain Prot_ATP_ID_OB PF16450.5 CCU99392.1 - 0.025 14.6 0.1 0.066 13.2 0.1 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain NACHT PF05729.12 CCU99392.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 CCU99392.1 - 0.037 13.8 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 CCU99392.1 - 0.055 13.5 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 CCU99392.1 - 0.056 12.7 0.1 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.14 CCU99392.1 - 0.082 13.0 1.7 0.29 11.2 0.2 2.6 3 1 0 3 3 3 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 CCU99392.1 - 0.087 12.1 0.5 0.19 11.0 0.2 1.7 2 0 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.17 CCU99392.1 - 0.12 11.4 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DEAD PF00270.29 CCU99392.1 - 0.26 11.1 2.7 0.17 11.6 0.7 1.7 2 0 0 2 2 1 0 DEAD/DEAH box helicase Lgl_C PF08596.10 CCU99394.1 - 8.9e-21 74.0 0.0 1.3e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 CCU99394.1 - 3.4e-05 24.1 0.0 0.1 12.9 0.0 3.5 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCU99394.1 - 0.051 14.5 0.3 5.8 8.0 0.0 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat AMP-binding PF00501.28 CCU99396.1 - 5.4e-53 180.1 0.4 1.9e-27 95.9 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CCU99396.1 - 1.4e-11 45.2 0.3 3.6e-11 43.9 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ank_5 PF13857.6 CCU99397.1 - 0.0018 18.6 0.1 2.6 8.5 0.0 2.9 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCU99397.1 - 0.026 15.1 0.0 0.053 14.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCU99397.1 - 0.11 13.1 0.1 0.29 11.8 0.1 1.9 1 1 0 1 1 1 0 Ankyrin repeats (many copies) GFO_IDH_MocA PF01408.22 CCU99398.1 - 5.1e-16 59.6 0.1 8.8e-16 58.8 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CCU99398.1 - 7.4e-09 35.6 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 CCU99398.1 - 0.034 14.8 0.1 0.058 14.0 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Cellulase PF00150.18 CCU99399.1 - 1.8e-16 60.4 2.2 2.5e-16 59.9 2.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GRASP55_65 PF04495.14 CCU99400.1 - 2.3e-41 141.4 0.0 3.6e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 CCU99400.1 - 2.8e-06 27.1 0.0 4.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CCU99400.1 - 0.016 15.5 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 PDZ domain GMC_oxred_N PF00732.19 CCU99402.1 - 2.4e-68 230.7 2.2 3e-68 230.4 2.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CCU99402.1 - 1.2e-33 116.6 0.0 2.4e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CCU99402.1 - 4.8e-05 22.6 0.0 7.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CCU99402.1 - 9.1e-05 21.8 0.1 0.00035 19.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CCU99402.1 - 0.00014 21.1 1.6 0.0084 15.2 1.2 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 CCU99402.1 - 0.00019 21.6 0.8 0.00067 19.8 0.8 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CCU99402.1 - 0.00046 19.0 0.9 0.012 14.4 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 CCU99402.1 - 0.00064 19.4 2.1 0.0051 16.4 0.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CCU99402.1 - 0.0047 16.2 0.1 0.092 12.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCU99402.1 - 0.017 14.4 0.1 0.048 12.9 0.1 1.7 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 CCU99402.1 - 0.028 13.7 0.1 0.048 12.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 CCU99402.1 - 0.081 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 CCU99402.1 - 0.16 12.2 0.1 0.4 11.0 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 CCU99402.1 - 0.21 12.2 0.7 0.46 11.1 0.3 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase UPF0029 PF01205.19 CCU99404.1 - 6e-30 103.7 0.0 1.2e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CCU99404.1 - 1.4e-06 28.6 0.0 2.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain Pkinase PF00069.25 CCU99405.1 - 3.8e-12 46.1 0.0 6.2e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99405.1 - 1.4e-07 31.1 0.0 3.1e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RabGAP-TBC PF00566.18 CCU99406.1 - 9.3e-51 172.5 0.2 1.5e-50 171.8 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 CCU99406.1 - 6.4e-06 26.0 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 GRAM domain FA_hydroxylase PF04116.13 CCU99407.1 - 1.3e-23 83.9 20.7 1.3e-23 83.9 20.7 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Aa_trans PF01490.18 CCU99408.1 - 1.2e-68 231.7 26.9 1.6e-68 231.3 26.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NTF2 PF02136.20 CCU99410.1 - 3.5e-08 34.1 0.0 6.9e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 CCU99410.1 - 2.8e-06 27.4 0.0 5.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DUF383 PF04063.14 CCU99411.1 - 2.2e-57 193.8 0.0 7.8e-57 192.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CCU99411.1 - 1.6e-18 66.3 0.5 3.6e-18 65.1 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF1281 PF06924.11 CCU99412.1 - 0.018 14.6 0.1 0.26 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) Ank_2 PF12796.7 CCU99413.1 - 4.5e-29 100.9 0.0 3e-15 56.6 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) DHHC PF01529.20 CCU99413.1 - 1.9e-28 99.2 9.8 1.9e-28 99.2 9.8 2.8 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank PF00023.30 CCU99413.1 - 4.4e-26 90.1 5.7 5.1e-07 29.9 0.1 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CCU99413.1 - 1.3e-23 82.8 3.2 1.8e-07 31.3 0.1 4.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCU99413.1 - 2.6e-23 82.1 0.6 1.5e-07 31.9 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCU99413.1 - 3.3e-22 76.2 2.6 9e-06 25.7 0.1 5.8 6 0 0 6 6 6 4 Ankyrin repeat Biotin_lipoyl PF00364.22 CCU99414.1 - 1.4e-16 60.0 1.7 2.5e-16 59.2 1.7 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CCU99414.1 - 4.1e-08 33.4 0.0 2.4e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CCU99414.1 - 0.00067 19.4 0.3 0.0073 16.1 0.0 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like YqfD PF06898.11 CCU99414.1 - 0.18 10.6 0.9 4.6 6.0 0.4 2.1 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD Ribosomal_60s PF00428.19 CCU99414.1 - 0.67 10.6 10.4 7.4 7.2 0.1 3.0 2 1 0 2 2 2 0 60s Acidic ribosomal protein Diphthamide_syn PF01866.17 CCU99415.1 - 7.8e-88 294.8 0.0 3.7e-86 289.3 0.0 2.3 1 1 0 1 1 1 1 Putative diphthamide synthesis protein COQ7 PF03232.13 CCU99416.1 - 5e-65 218.5 0.8 5.8e-65 218.2 0.8 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 CCU99416.1 - 0.0012 19.2 0.0 0.0024 18.3 0.0 1.5 1 1 0 1 1 1 1 Rubrerythrin Peptidase_M9_N PF08453.10 CCU99416.1 - 0.097 12.4 0.0 0.3 10.8 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M9 N-terminal DUF3849 PF12960.7 CCU99416.1 - 0.11 12.5 0.0 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3849) ATP13 PF12921.7 CCU99416.1 - 0.13 12.2 0.0 11 5.9 0.0 2.4 1 1 1 2 2 2 0 Mitochondrial ATPase expression Mito_carr PF00153.27 CCU99417.1 - 2.1e-32 110.9 5.6 1.8e-15 56.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Dak1 PF02733.17 CCU99418.1 - 3.1e-97 325.2 0.7 5.3e-97 324.5 0.7 1.4 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CCU99418.1 - 1.1e-50 172.0 1.5 1.8e-50 171.2 1.5 1.4 1 0 0 1 1 1 1 DAK2 domain Pep3_Vps18 PF05131.14 CCU99419.1 - 1.4e-28 99.6 0.0 1.4e-27 96.3 0.0 2.5 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CCU99419.1 - 0.00016 21.6 0.3 0.0011 18.9 0.1 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 CCU99419.1 - 0.0012 19.2 0.0 0.0033 17.9 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 CCU99419.1 - 0.033 13.9 4.3 0.09 12.5 4.3 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 CCU99419.1 - 0.033 14.5 0.7 0.033 14.5 0.7 2.2 3 0 0 3 3 3 0 RING-H2 zinc finger domain RPN1_RPN2_N PF17781.1 CCU99419.1 - 0.2 11.0 1.1 0.33 10.3 0.1 1.8 2 0 0 2 2 2 0 RPN1/RPN2 N-terminal domain zf-ANAPC11 PF12861.7 CCU99419.1 - 1.1 9.3 3.9 0.53 10.4 0.4 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CCU99419.1 - 1.4 8.6 5.3 0.29 10.8 1.0 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CCU99419.1 - 3.2 7.7 12.8 0.037 13.9 3.5 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCU99419.1 - 5.1 7.2 9.0 0.094 12.7 1.4 2.1 2 0 0 2 2 2 0 zinc-RING finger domain WD40 PF00400.32 CCU99420.1 - 2.2e-08 34.6 2.0 3 8.8 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Sec16_C PF12931.7 CCU99420.1 - 0.04 13.6 0.1 0.21 11.2 0.0 2.2 2 1 0 2 2 2 0 Sec23-binding domain of Sec16 Ssl1 PF04056.14 CCU99421.1 - 7.7e-25 87.8 0.0 1.8e-24 86.6 0.0 1.6 1 1 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 CCU99421.1 - 3.5e-08 34.0 0.0 4.5e-07 30.5 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain RD3 PF14473.6 CCU99421.1 - 0.041 13.7 0.5 0.068 13.0 0.5 1.3 1 0 0 1 1 1 0 RD3 protein ThrE PF06738.12 CCU99422.1 - 3.2e-55 187.1 6.6 3.2e-55 187.1 6.6 2.4 2 0 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 CCU99422.1 - 4.9e-07 29.9 8.0 4.9e-07 29.9 8.0 2.7 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE DUF3339 PF11820.8 CCU99422.1 - 0.067 13.4 0.2 0.067 13.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3339) zf-CHCC PF10276.9 CCU99423.1 - 1.8e-09 37.5 0.0 3.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger domain Ribophorin_I PF04597.14 CCU99425.1 - 1.6e-80 271.5 0.0 1.8e-80 271.3 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I RRM_1 PF00076.22 CCU99426.1 - 2.1e-17 62.7 0.0 3.6e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF724 PF05266.14 CCU99426.1 - 0.029 14.2 1.0 0.04 13.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TolA_bind_tri PF16331.5 CCU99426.1 - 0.094 12.8 0.3 0.17 12.0 0.3 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation DivIC PF04977.15 CCU99426.1 - 0.1 12.4 0.4 0.16 11.8 0.4 1.3 1 0 0 1 1 1 0 Septum formation initiator Nup35_RRM_2 PF14605.6 CCU99426.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Aminotran_5 PF00266.19 CCU99427.1 - 5.4e-75 252.7 0.0 1.2e-74 251.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CCU99427.1 - 0.043 13.1 0.1 0.069 12.4 0.1 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase RVP_2 PF08284.11 CCU99427.1 - 0.072 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease WD40 PF00400.32 CCU99428.1 - 1.7e-25 88.8 8.3 2.6e-05 24.9 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU99428.1 - 7.7e-18 64.6 0.2 0.0024 18.1 0.0 6.4 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCU99428.1 - 5.9e-05 23.0 0.0 9.1 6.1 0.0 4.1 3 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CCU99428.1 - 0.00098 17.9 0.0 0.0014 17.3 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PD40 PF07676.12 CCU99428.1 - 0.001 18.9 0.7 2.8 8.0 0.0 3.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 CCU99428.1 - 0.019 13.0 0.0 0.11 10.5 0.0 1.9 2 0 0 2 2 2 0 IKI3 family MIS13 PF08202.11 CCU99429.1 - 1.1e-19 70.9 7.4 2e-18 66.7 7.4 2.3 1 1 0 1 1 1 1 Mis12-Mtw1 protein family CENP-O PF09496.10 CCU99429.1 - 0.029 14.4 0.6 0.057 13.4 0.6 1.6 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component ABC_tran_CTD PF16326.5 CCU99429.1 - 0.071 13.4 2.2 0.3 11.3 0.4 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain HA2 PF04408.23 CCU99430.1 - 3.6e-16 59.4 0.0 8.9e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCU99430.1 - 4.5e-14 52.7 0.0 1.7e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain dsrm PF00035.26 CCU99430.1 - 1.6e-12 47.9 0.0 1.6e-05 25.5 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.16 CCU99430.1 - 1.8e-05 25.0 0.0 5.3e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CCU99430.1 - 0.00029 20.7 0.1 0.00064 19.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase LRR_6 PF13516.6 CCU99431.1 - 6.7e-06 25.7 0.0 0.96 9.7 0.0 4.9 5 0 0 5 5 5 3 Leucine Rich repeat WD40 PF00400.32 CCU99432.1 - 3.9e-21 75.0 11.6 0.0034 18.2 0.0 9.2 9 0 0 9 9 9 5 WD domain, G-beta repeat CTP_transf_like PF01467.26 CCU99432.1 - 3.8e-06 27.2 0.0 9.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like ANAPC4_WD40 PF12894.7 CCU99432.1 - 0.00052 20.3 0.0 0.0066 16.7 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain HA2 PF04408.23 CCU99434.1 - 9e-22 77.4 0.0 9.9e-21 74.1 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CCU99434.1 - 1.3e-18 67.1 0.2 3.3e-18 65.8 0.1 1.7 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CCU99434.1 - 2.2e-14 53.8 0.0 4.3e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCU99434.1 - 4.9e-06 26.4 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCU99434.1 - 6.7e-06 26.4 0.0 2.2e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCU99434.1 - 0.00017 21.3 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CCU99434.1 - 0.00047 19.3 0.0 0.00091 18.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CCU99434.1 - 0.0012 19.2 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CCU99434.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CCU99434.1 - 0.045 14.1 0.1 0.045 14.1 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CCU99434.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 CCU99434.1 - 0.099 12.6 0.2 0.71 9.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 CCU99434.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein zf-HC5HC2H_2 PF13832.6 CCU99435.1 - 1.9e-32 111.7 3.2 1.9e-32 111.7 3.2 2.9 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CCU99435.1 - 1.4e-24 86.2 0.6 1.4e-24 86.2 0.6 3.3 4 0 0 4 4 4 1 PHD-like zinc-binding domain EPL1 PF10513.9 CCU99435.1 - 2.6e-20 73.4 5.7 2.6e-20 73.4 5.7 1.6 2 0 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.6 CCU99435.1 - 7.8e-15 54.1 2.8 7.8e-15 54.1 2.8 3.1 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 CCU99435.1 - 2.4e-09 37.0 9.2 2.4e-09 37.0 9.2 3.0 3 0 0 3 3 3 2 PHD-finger Bromodomain PF00439.25 CCU99435.1 - 2.4e-08 34.0 0.0 4.6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain zf-PHD-like PF15446.6 CCU99435.1 - 0.0066 16.1 2.1 0.0066 16.1 2.1 2.6 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain PHD_3 PF13922.6 CCU99435.1 - 0.053 13.9 3.0 0.17 12.3 3.0 1.9 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx C1_1 PF00130.22 CCU99435.1 - 2.5 8.1 15.1 0.046 13.6 1.7 3.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA PF00004.29 CCU99436.1 - 2.4e-52 176.8 0.0 1e-41 142.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCU99436.1 - 1.9e-07 30.8 0.0 9.1e-07 28.6 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain IstB_IS21 PF01695.17 CCU99436.1 - 2.2e-07 30.8 0.0 6.8e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 CCU99436.1 - 2.7e-06 27.8 9.8 7.1e-05 23.3 0.1 4.1 4 2 0 4 4 4 2 AAA ATPase domain AAA_2 PF07724.14 CCU99436.1 - 1.7e-05 25.0 0.0 3.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCU99436.1 - 8.7e-05 22.5 0.2 0.017 15.1 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 CCU99436.1 - 0.00027 21.1 0.0 0.41 10.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 CCU99436.1 - 0.0013 19.0 0.2 0.14 12.5 0.2 3.7 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.12 CCU99436.1 - 0.0022 17.7 0.0 0.48 10.2 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CCU99436.1 - 0.0061 16.0 0.1 0.22 10.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CCU99436.1 - 0.0088 16.2 0.4 0.054 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCU99436.1 - 0.011 16.3 1.3 0.029 14.9 0.0 2.5 3 0 0 3 3 1 0 AAA domain Bromodomain PF00439.25 CCU99436.1 - 0.011 15.8 0.1 0.024 14.7 0.1 1.5 1 0 0 1 1 1 0 Bromodomain Sigma54_activat PF00158.26 CCU99436.1 - 0.018 14.7 0.0 0.95 9.1 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain TIP49 PF06068.13 CCU99436.1 - 0.032 13.4 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_30 PF13604.6 CCU99436.1 - 0.033 13.9 0.0 0.092 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CCU99436.1 - 0.035 13.2 0.0 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CCU99436.1 - 0.041 13.5 0.5 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCU99436.1 - 0.043 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SMN PF06003.12 CCU99436.1 - 0.051 12.8 0.9 0.13 11.5 0.9 1.7 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) AAA_3 PF07726.11 CCU99436.1 - 0.053 13.4 0.0 0.48 10.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 CCU99436.1 - 0.06 13.4 0.0 0.75 9.9 0.0 2.3 2 0 0 2 2 2 0 Torsin DUF2075 PF09848.9 CCU99436.1 - 0.081 12.1 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 CCU99436.1 - 0.09 12.8 0.0 0.55 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CCU99436.1 - 0.094 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 CCU99436.1 - 0.098 12.1 0.2 0.58 9.6 0.0 2.2 3 0 0 3 3 3 0 PhoH-like protein AAA_7 PF12775.7 CCU99436.1 - 0.14 11.6 0.0 0.39 10.2 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 CCU99436.1 - 0.29 10.9 0.0 0.29 10.9 0.0 3.5 4 0 0 4 4 4 0 AAA domain DnaJ_C PF01556.18 CCU99437.1 - 7.1e-35 120.3 0.0 9.6e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCU99437.1 - 2.6e-26 91.5 2.2 3.7e-26 91.0 2.2 1.2 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 CCU99437.1 - 0.087 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 A repeated domain in UCH-protein Ribosomal_L7Ae PF01248.26 CCU99438.1 - 5.7e-27 93.3 0.2 7.2e-27 93.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CCU99438.1 - 0.0018 18.1 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CCU99438.1 - 0.0038 17.3 0.1 0.0042 17.2 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 CRAL_TRIO PF00650.20 CCU99439.1 - 3.7e-27 95.0 0.0 6.1e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCU99439.1 - 1.4e-10 41.2 0.4 4.3e-10 39.6 0.4 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CCU99439.1 - 4.9e-09 36.5 0.0 9.3e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Dimerisation PF08100.11 CCU99439.1 - 0.2 11.7 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Lipase_3 PF01764.25 CCU99440.1 - 4.2e-22 78.5 0.0 6.2e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CCU99440.1 - 0.00066 19.0 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 CCU99440.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 CCU99440.1 - 0.011 16.4 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 CCU99440.1 - 0.016 13.7 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II VirJ PF06057.11 CCU99440.1 - 0.065 13.1 0.0 0.097 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PGAP1 PF07819.13 CCU99440.1 - 0.13 12.0 0.2 0.21 11.3 0.2 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 CCU99441.1 - 2e-18 66.7 0.0 2.8e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PAF-AH_p_II PF03403.13 CCU99441.1 - 0.0018 16.9 0.0 0.0028 16.2 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 CCU99441.1 - 0.0053 17.4 0.0 0.0074 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CCU99441.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 CCU99441.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FSH1 PF03959.13 CCU99441.1 - 0.033 13.8 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 CCU99441.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF915 PF06028.11 CCU99441.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PFK PF00365.20 CCU99442.1 - 1.6e-160 532.9 0.0 2.7e-86 289.4 0.4 3.6 2 1 0 2 2 2 2 Phosphofructokinase OmpA PF00691.20 CCU99442.1 - 0.19 12.1 0.0 0.61 10.5 0.0 1.8 2 0 0 2 2 2 0 OmpA family LSM PF01423.22 CCU99443.1 - 1.7e-15 56.4 0.3 2.2e-15 56.1 0.3 1.1 1 0 0 1 1 1 1 LSM domain CCT_2 PF09425.10 CCU99443.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Divergent CCT motif PROCN PF08083.11 CCU99444.1 - 2.4e-232 770.8 6.5 2.8e-231 767.4 7.1 2.1 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CCU99444.1 - 7.6e-125 415.1 0.4 1.3e-124 414.3 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CCU99444.1 - 4e-87 290.1 3.3 4.5e-87 289.9 1.2 2.2 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CCU99444.1 - 1.3e-83 278.5 5.6 1.5e-83 278.2 3.4 2.2 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CCU99444.1 - 2.5e-69 231.5 0.0 5.9e-69 230.3 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 CCU99444.1 - 9.5e-45 150.9 0.4 2.2e-44 149.7 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 CCU99444.1 - 3e-37 127.3 0.0 5.7e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain DUF410 PF04190.13 CCU99444.1 - 3.8e-08 33.4 4.6 0.00041 20.2 0.0 3.9 2 1 1 3 3 3 2 Protein of unknown function (DUF410) JAB PF01398.21 CCU99444.1 - 0.00011 22.1 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3402 PF11882.8 CCU99446.1 - 1.1e-102 344.5 0.0 1.8e-100 337.2 0.0 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 CCU99446.1 - 1.3e-23 83.7 0.0 1.2e-11 44.4 0.0 3.2 1 1 2 3 3 3 3 N1221-like protein DDOST_48kD PF03345.14 CCU99447.1 - 4.9e-132 440.7 0.0 5.7e-132 440.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Diphthami_syn_2 PF01902.17 CCU99448.1 - 3.7e-35 121.4 0.0 1.9e-24 86.4 0.0 2.1 2 0 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 CCU99448.1 - 3.3e-15 56.2 0.0 1.1e-08 35.1 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP SUV3_C PF12513.8 CCU99449.1 - 4.9e-15 55.2 0.4 1e-14 54.2 0.4 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CCU99449.1 - 1.5e-12 47.8 0.0 3.7e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromo_TP PF07524.13 CCU99450.1 - 4.9e-05 23.3 0.1 0.00012 22.1 0.1 1.6 1 0 0 1 1 1 1 Bromodomain associated Peptidase_S10 PF00450.22 CCU99452.1 - 1.7e-36 126.6 0.8 1.8e-25 90.2 0.1 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase FA_desaturase PF00487.24 CCU99453.1 - 2.7e-14 53.6 22.4 2.7e-14 53.6 22.4 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 CCU99453.1 - 2.9e-14 53.0 0.1 6.5e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_hydro_47 PF01532.20 CCU99455.1 - 1.7e-141 472.3 0.0 2.1e-141 471.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HAD_2 PF13419.6 CCU99455.1 - 0.039 14.0 0.0 0.21 11.6 0.0 2.1 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Rap_GAP PF02145.15 CCU99456.1 - 9.4e-45 152.4 0.0 1.5e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP DUF3384 PF11864.8 CCU99456.1 - 9.6e-45 153.4 0.1 1.6e-44 152.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Tuberin PF03542.16 CCU99456.1 - 1.2e-36 126.6 4.5 6.4e-35 120.9 2.1 3.6 2 1 0 2 2 2 1 Tuberin Redoxin PF08534.10 CCU99457.1 - 7.5e-32 110.1 0.0 8.3e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CCU99457.1 - 2.1e-08 34.1 0.0 2.3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family LSM PF01423.22 CCU99458.1 - 1.3e-18 66.5 0.1 1.5e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCU99458.1 - 0.0009 19.3 0.1 0.0013 18.8 0.1 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CCU99458.1 - 0.011 15.8 0.1 0.013 15.6 0.1 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain GRDB PF07355.12 CCU99458.1 - 0.032 13.5 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) CENP-W PF15510.6 CCU99458.1 - 0.2 11.9 0.0 0.25 11.6 0.0 1.3 1 1 0 1 1 1 0 CENP-W protein DUF3395 PF11875.8 CCU99459.1 - 6.5e-46 156.1 0.0 1.1e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CCU99459.1 - 2.6e-22 78.7 1.8 5.6e-22 77.6 1.8 1.6 1 0 0 1 1 1 1 DnaJ domain PAPS_reduct PF01507.19 CCU99460.1 - 7.5e-42 143.3 0.0 9.5e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ribosomal_L4 PF00573.22 CCU99461.1 - 7.6e-41 139.9 0.4 1.2e-40 139.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CCU99461.1 - 1.5e-28 98.7 5.1 1.9e-28 98.3 0.3 2.9 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain COesterase PF00135.28 CCU99462.1 - 6.5e-60 203.5 0.7 7.3e-58 196.7 0.3 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CCU99462.1 - 0.019 14.8 0.0 0.059 13.2 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Pyr_redox_2 PF07992.14 CCU99463.1 - 5e-50 170.4 0.1 5.7e-50 170.2 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCU99463.1 - 6.9e-16 58.4 0.1 2.5e-12 46.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCU99463.1 - 7.9e-16 58.4 0.1 3.7e-13 49.8 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCU99463.1 - 2.3e-06 27.2 0.1 0.00093 18.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 CCU99463.1 - 1.2e-05 24.7 0.1 4.9e-05 22.7 0.1 1.9 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 CCU99463.1 - 3.3e-05 23.2 0.1 0.026 13.7 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 CCU99463.1 - 0.00025 20.3 4.2 0.0063 15.7 0.6 3.3 3 1 1 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CCU99463.1 - 0.00053 19.2 1.7 0.0024 17.0 0.6 2.4 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 CCU99463.1 - 0.0012 19.1 0.7 0.017 15.4 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CCU99463.1 - 0.0032 17.1 1.8 0.019 14.6 1.8 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CCU99463.1 - 0.0037 16.6 0.4 0.022 14.0 0.0 2.1 2 1 1 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 CCU99463.1 - 0.007 16.8 0.1 0.19 12.2 0.0 2.7 2 2 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 CCU99463.1 - 0.019 13.8 0.2 0.083 11.7 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 CCU99463.1 - 0.021 13.5 0.1 0.07 11.8 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein Aconitase PF00330.20 CCU99464.1 - 3e-147 491.3 0.0 4e-147 491.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCU99464.1 - 4.2e-43 146.8 0.0 7.1e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain CS PF04969.16 CCU99465.1 - 0.0018 19.3 0.1 0.0038 18.2 0.1 1.5 1 0 0 1 1 1 1 CS domain RRM_1 PF00076.22 CCU99466.1 - 1.5e-17 63.1 0.0 3e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BNIP2 PF12496.8 CCU99466.1 - 0.014 15.8 6.4 0.024 15.1 6.4 1.4 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DNA_pol_phi PF04931.13 CCU99466.1 - 0.11 10.6 16.3 0.15 10.2 16.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 CCU99466.1 - 3.4 6.8 5.7 6.3 5.9 5.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Astro_capsid_p PF12226.8 CCU99466.1 - 3.6 6.6 12.0 5.4 6.1 12.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RNA_pol_3_Rpc31 PF11705.8 CCU99466.1 - 9 6.5 17.8 14 5.9 14.4 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 PRMT5_TIM PF17285.2 CCU99467.1 - 4.2e-66 222.8 0.0 6e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 CCU99467.1 - 1.6e-54 184.4 0.0 2.5e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 CCU99467.1 - 1.7e-52 177.8 0.0 2.7e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 CCU99467.1 - 0.00013 22.6 0.0 0.00028 21.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCU99467.1 - 0.0059 17.2 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.8 CCU99467.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Acetyltransf_1 PF00583.25 CCU99468.1 - 1.7e-10 41.2 0.0 2.4e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCU99468.1 - 1.5e-08 35.0 0.0 2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CCU99468.1 - 0.00011 22.1 0.0 0.00019 21.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCU99468.1 - 0.00012 21.9 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CCU99468.1 - 0.1 12.7 0.0 0.35 10.9 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Actin PF00022.19 CCU99469.1 - 2.9e-82 276.5 0.0 3.1e-81 273.1 0.0 1.9 1 1 0 1 1 1 1 Actin FtsA PF14450.6 CCU99469.1 - 0.055 13.9 0.0 0.2 12.1 0.0 2.0 1 1 0 1 1 1 0 Cell division protein FtsA Macoilin PF09726.9 CCU99471.1 - 0.0053 15.4 19.8 0.0058 15.3 19.8 1.2 1 0 0 1 1 1 1 Macoilin family XRN_M PF17846.1 CCU99472.1 - 5e-95 319.1 8.8 3.3e-94 316.3 8.8 2.0 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CCU99472.1 - 5.6e-73 245.3 0.0 1.2e-72 244.3 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 CCU99472.1 - 1e-44 152.6 0.0 2.5e-44 151.4 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 CCU99472.1 - 4e-21 74.9 0.3 1e-20 73.6 0.3 1.8 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 CCU99472.1 - 1.1e-18 67.3 0.1 5.9e-18 64.9 0.0 2.4 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain DehI PF10778.9 CCU99472.1 - 0.15 12.2 0.4 2.1 8.5 0.1 2.3 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI Patatin PF01734.22 CCU99473.1 - 3.2e-15 56.9 0.1 1.3e-11 45.1 0.2 2.7 1 1 1 2 2 2 2 Patatin-like phospholipase DUF3336 PF11815.8 CCU99473.1 - 2.4e-11 43.5 0.0 4.6e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) AIP3 PF03915.13 CCU99474.1 - 5.9e-123 411.0 0.5 6.7e-123 410.8 0.5 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 CHDCT2 PF08074.11 CCU99474.1 - 0.0034 17.6 2.1 0.12 12.5 0.1 2.5 1 1 1 2 2 2 1 CHDCT2 (NUC038) domain DUF1640 PF07798.11 CCU99474.1 - 0.021 14.9 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Syntaxin-6_N PF09177.11 CCU99474.1 - 0.072 13.7 3.4 14 6.4 0.2 3.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Baculo_p24 PF05073.12 CCU99474.1 - 0.093 12.5 0.1 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Baculovirus P24 capsid protein Rota_NSP3 PF01665.16 CCU99474.1 - 0.12 11.4 0.1 0.22 10.6 0.1 1.4 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 Laminin_II PF06009.12 CCU99474.1 - 0.15 12.0 2.8 4.9 7.2 0.1 2.8 2 0 0 2 2 2 0 Laminin Domain II Prominin PF05478.11 CCU99474.1 - 0.29 9.0 0.6 0.92 7.4 0.1 1.9 1 1 1 2 2 2 0 Prominin ERCC3_RAD25_C PF16203.5 CCU99475.1 - 8.7e-122 405.1 0.3 1.6e-121 404.2 0.3 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CCU99475.1 - 8.2e-38 129.4 0.0 2.1e-37 128.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU99475.1 - 5.2e-18 65.6 0.0 9.4e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCU99475.1 - 2e-11 44.2 0.1 7.1e-11 42.4 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CCU99475.1 - 2.1e-09 36.6 0.0 3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 CCU99475.1 - 1.1e-05 25.3 0.1 2.2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SHR3_chaperone PF08229.11 CCU99476.1 - 3.8e-18 65.2 0.1 4.1e-18 65.0 0.1 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Pex24p PF06398.11 CCU99476.1 - 0.16 10.9 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Aldo_ket_red PF00248.21 CCU99477.1 - 2.9e-48 164.6 0.2 2.3e-47 161.6 0.2 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family FTCD_N PF07837.12 CCU99477.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain Sad1_UNC PF07738.13 CCU99478.1 - 7.6e-32 110.1 0.0 1.6e-14 54.0 0.0 2.3 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal EzrA PF06160.12 CCU99478.1 - 0.00036 18.9 5.6 0.0012 17.1 5.6 1.7 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA CSN5_C PF18323.1 CCU99478.1 - 0.064 14.2 3.4 1.3 10.0 0.1 3.4 3 0 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain CLZ PF16526.5 CCU99478.1 - 0.095 13.1 0.2 0.095 13.1 0.2 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HAD PF12710.7 CCU99478.1 - 0.13 12.6 3.0 0.39 11.1 0.3 2.9 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Fib_alpha PF08702.10 CCU99478.1 - 0.22 11.7 9.6 0.16 12.2 2.0 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family CCDC-167 PF15188.6 CCU99478.1 - 0.22 11.9 8.7 0.93 9.9 0.2 3.0 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Laminin_II PF06009.12 CCU99478.1 - 0.33 11.0 3.9 2.4 8.2 0.1 2.6 2 0 0 2 2 2 0 Laminin Domain II VPDSG-CTERM PF18205.1 CCU99478.1 - 0.39 10.6 7.9 1 9.3 7.9 1.7 1 0 0 1 1 1 0 VPDSG-CTERM motif CENP-F_leu_zip PF10473.9 CCU99478.1 - 0.44 10.6 10.3 0.38 10.8 2.3 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM184 PF15665.5 CCU99478.1 - 1.2 8.8 20.5 9.1e+02 -0.5 20.5 2.3 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B DUF1993 PF09351.10 CCU99478.1 - 1.7 8.8 5.6 1.5 8.9 0.3 2.9 1 1 1 4 4 4 0 Domain of unknown function (DUF1993) Prefoldin_2 PF01920.20 CCU99478.1 - 5.3 7.0 11.8 0.45 10.5 0.8 3.1 4 0 0 4 4 4 0 Prefoldin subunit BST2 PF16716.5 CCU99478.1 - 6.6 7.4 8.0 31 5.2 1.6 3.1 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 DUF745 PF05335.13 CCU99478.1 - 9.8 5.9 14.1 0.51 10.0 2.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Y_phosphatase2 PF03162.13 CCU99479.1 - 4.7e-25 88.1 0.0 7.6e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Brr6_like_C_C PF10104.9 CCU99480.1 - 4.2e-29 101.0 3.2 6.4e-21 74.5 0.1 2.1 1 1 1 2 2 2 2 Di-sulfide bridge nucleocytoplasmic transport domain DNApol_Exo PF18136.1 CCU99481.1 - 2.3e-82 276.3 0.0 5.5e-80 268.5 0.0 2.3 1 1 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CCU99481.1 - 9.1e-47 159.9 0.0 1.6e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A RA PF00788.23 CCU99482.1 - 0.055 14.1 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain FMO-like PF00743.19 CCU99484.1 - 1.5e-19 69.8 0.0 1.1e-18 66.9 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CCU99484.1 - 1.5e-15 57.3 0.0 9.4e-14 51.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCU99484.1 - 2.8e-15 56.4 0.0 5.2e-12 45.6 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCU99484.1 - 1.5e-10 41.5 0.8 0.00015 22.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CCU99484.1 - 1.3e-09 38.2 1.6 6.9e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CCU99484.1 - 2e-09 37.3 0.0 1e-05 25.0 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 CCU99484.1 - 2.3e-09 37.3 1.1 3.4e-06 26.9 0.1 3.3 4 0 0 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 CCU99484.1 - 2.9e-09 36.5 0.0 1.1e-06 28.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 CCU99484.1 - 1.3e-08 34.4 0.2 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CCU99484.1 - 2.1e-05 23.9 1.1 0.0044 16.3 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 CCU99484.1 - 2.7e-05 23.4 4.8 0.0006 19.0 0.5 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 CCU99484.1 - 3e-05 24.1 3.4 0.0005 20.1 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding GIDA PF01134.22 CCU99484.1 - 3.2e-05 23.2 2.5 0.045 12.8 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 CCU99484.1 - 3.9e-05 24.0 0.0 0.051 14.0 0.0 2.4 2 1 0 2 2 2 2 Putative NAD(P)-binding FAD_oxidored PF12831.7 CCU99484.1 - 8.9e-05 22.0 0.1 0.27 10.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 CCU99484.1 - 0.0001 21.7 1.2 0.045 13.0 0.2 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 CCU99484.1 - 0.00013 20.8 2.6 0.086 11.5 0.3 2.2 2 0 0 2 2 2 2 HI0933-like protein Shikimate_DH PF01488.20 CCU99484.1 - 0.00024 21.2 0.0 0.59 10.2 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CCU99484.1 - 0.0021 18.0 0.2 0.0048 16.8 0.2 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 CCU99484.1 - 0.044 13.1 0.0 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 ThiF family 2-Hacid_dh_C PF02826.19 CCU99484.1 - 0.063 12.6 0.0 3 7.2 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 CCU99484.1 - 0.16 11.0 0.2 1.8 7.5 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Ldh_1_N PF00056.23 CCU99484.1 - 0.23 11.5 0.2 4.8 7.3 0.0 2.5 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Methyltr_RsmB-F PF01189.17 CCU99485.1 - 5.6e-72 241.6 0.0 9.1e-72 240.9 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CCU99485.1 - 1.2e-06 28.9 0.0 2.9e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 CCU99485.1 - 0.033 14.3 0.0 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 CCU99485.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DNA_pol_B PF00136.21 CCU99486.1 - 4.2e-137 457.6 0.7 5.7e-137 457.2 0.7 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CCU99486.1 - 2.5e-53 181.4 0.0 5.9e-53 180.2 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 CCU99486.1 - 0.002 17.1 0.2 0.0069 15.3 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral BMC PF00936.19 CCU99486.1 - 0.027 14.5 2.1 0.8 9.7 0.2 2.5 2 0 0 2 2 2 0 BMC domain DNA_pol_B_exo2 PF10108.9 CCU99486.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CCU99486.1 - 0.081 12.9 0.1 1.5 8.8 0.1 2.9 2 1 0 2 2 2 0 RNase_H superfamily Lon_C PF05362.13 CCU99487.1 - 1.7e-64 217.1 0.1 3.7e-64 216.1 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CCU99487.1 - 3.9e-21 75.9 0.0 2.3e-20 73.3 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 CCU99487.1 - 3.4e-10 40.1 0.1 3.4e-10 40.1 0.1 1.6 2 0 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 CCU99487.1 - 1.8e-06 27.8 0.0 6.1e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 CCU99487.1 - 2.2e-06 27.7 0.0 4.9e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 CCU99487.1 - 2.3e-05 23.5 0.2 4.7e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 PrkA AAA domain AAA_2 PF07724.14 CCU99487.1 - 3.3e-05 24.1 0.0 0.0001 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CCU99487.1 - 0.00014 22.4 0.7 0.00079 20.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CCU99487.1 - 0.00018 21.3 0.0 0.0017 18.1 0.0 2.3 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCU99487.1 - 0.00031 21.0 0.1 0.0082 16.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 CCU99487.1 - 0.0013 18.9 0.1 0.13 12.3 0.1 2.6 2 0 0 2 2 2 1 Shikimate kinase AAA_16 PF13191.6 CCU99487.1 - 0.0025 18.2 0.1 0.011 16.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 CCU99487.1 - 0.0067 15.7 0.1 0.027 13.7 0.1 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_28 PF13521.6 CCU99487.1 - 0.019 15.2 0.4 7.3 6.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 CCU99487.1 - 0.027 14.5 0.0 0.069 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CCU99487.1 - 0.029 14.1 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CCU99487.1 - 0.034 14.5 0.0 0.073 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ClpB_D2-small PF10431.9 CCU99487.1 - 0.047 13.8 3.8 0.1 12.6 0.2 3.1 4 0 0 4 4 2 0 C-terminal, D2-small domain, of ClpB protein RsgA_GTPase PF03193.16 CCU99487.1 - 0.059 13.3 0.4 0.14 12.1 0.0 1.8 2 0 0 2 2 1 0 RsgA GTPase Rad17 PF03215.15 CCU99487.1 - 0.061 13.2 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 CCU99487.1 - 0.074 12.8 0.1 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CCU99487.1 - 0.077 12.9 0.3 1.4 8.8 0.1 2.4 1 1 1 2 2 2 0 NTPase AAA_24 PF13479.6 CCU99487.1 - 0.089 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CCU99487.1 - 0.13 11.8 0.3 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region SMC_N PF02463.19 CCU99487.1 - 0.16 11.3 0.1 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.6 CCU99487.1 - 0.21 11.9 0.4 0.64 10.3 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CCU99487.1 - 0.58 10.6 9.3 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CCU99487.1 - 2.3 8.7 4.4 0.87 10.1 0.7 2.1 2 0 0 2 2 2 0 ABC transporter Ran_BP1 PF00638.18 CCU99489.1 - 3.1e-13 50.1 0.2 8.4e-13 48.6 0.2 1.7 1 1 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CCU99489.1 - 0.0025 17.7 0.1 0.0084 16.0 0.1 1.7 1 1 0 1 1 1 1 WH1 domain DUF5627 PF18620.1 CCU99489.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5627) Pro_isomerase PF00160.21 CCU99490.1 - 1.6e-39 135.8 0.0 3.1e-39 134.8 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M20 PF01546.28 CCU99490.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Bravo_FIGEY PF13882.6 CCU99490.1 - 3.8 8.9 7.9 0.52 11.7 0.8 2.5 2 0 0 2 2 2 0 Bravo-like intracellular region p450 PF00067.22 CCU99491.1 - 1.5e-59 202.0 0.2 9.4e-50 169.7 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 UDPGT PF00201.18 CCU99492.1 - 4.8e-09 35.5 0.1 1.9e-08 33.6 0.1 1.8 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Trimer_CC PF08954.11 CCU99492.1 - 0.0038 16.8 0.2 0.01 15.3 0.2 1.7 1 0 0 1 1 1 1 Trimerisation motif Ribosomal_S12 PF17487.2 CCU99492.1 - 0.058 14.1 0.2 0.14 12.9 0.2 1.6 1 0 0 1 1 1 0 Ribosomal protein S12 KH_1 PF00013.29 CCU99493.1 - 6.6e-44 147.6 9.5 2.2e-16 59.4 0.5 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CCU99493.1 - 2e-14 53.2 11.1 4e-06 26.5 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CCU99493.1 - 2.7e-07 30.4 3.9 0.51 10.2 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CCU99493.1 - 0.0008 19.5 7.1 0.79 9.8 0.2 3.8 3 1 0 3 3 3 2 NusA-like KH domain MIF4G PF02854.19 CCU99494.1 - 8.8e-39 133.3 0.0 1.3e-18 67.4 0.0 2.2 2 0 0 2 2 2 2 MIF4G domain Hexapep PF00132.24 CCU99495.1 - 2.2e-08 33.5 0.2 3.2e-05 23.5 0.9 2.9 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 CCU99495.1 - 0.00018 21.2 0.0 0.008 15.8 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep_2 PF14602.6 CCU99495.1 - 0.0016 18.2 3.3 0.0035 17.1 1.9 2.3 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CCU99495.1 - 0.0021 17.0 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 CCU99495.1 - 0.0029 15.8 0.2 0.011 13.9 0.2 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 CCU99495.1 - 0.0053 17.1 4.1 0.031 14.6 3.6 2.2 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF4781 PF16013.5 CCU99495.1 - 0.32 9.8 0.7 0.48 9.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) CDP-OH_P_transf PF01066.21 CCU99496.1 - 5.3e-14 52.7 1.4 9.9e-14 51.9 0.4 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ABC_membrane PF00664.23 CCU99497.1 - 9.2e-47 160.0 3.5 1.2e-46 159.6 3.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CCU99497.1 - 2.1e-31 109.3 0.0 3.5e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_ATPase PF09818.9 CCU99497.1 - 9.2e-05 21.4 0.0 0.00014 20.8 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 CCU99497.1 - 0.00031 21.2 0.0 0.00099 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 CCU99497.1 - 0.00044 19.6 0.0 0.00099 18.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin SMC_N PF02463.19 CCU99497.1 - 0.00077 19.0 0.1 0.038 13.4 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain PsbW PF07123.12 CCU99497.1 - 0.015 15.3 0.8 0.04 13.9 0.8 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) DUF815 PF05673.13 CCU99497.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 CCU99497.1 - 0.062 13.6 0.2 0.8 10.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCU99497.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain EPSP_synthase PF00275.20 CCU99498.1 - 5.5e-127 423.9 0.0 8.8e-127 423.3 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CCU99498.1 - 2.6e-94 315.2 0.1 2.6e-94 315.2 0.1 2.1 3 0 0 3 3 3 1 3-dehydroquinate synthase DHquinase_I PF01487.15 CCU99498.1 - 2.1e-49 168.8 0.0 5.5e-49 167.5 0.0 1.8 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.22 CCU99498.1 - 2.1e-26 93.0 0.0 6.4e-25 88.1 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 CCU99498.1 - 6e-25 87.3 0.0 2.3e-24 85.4 0.0 2.1 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 CCU99498.1 - 1e-08 35.3 0.0 2.5e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 CCU99498.1 - 1.8e-08 34.0 1.6 3e-08 33.3 0.2 2.2 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 CCU99498.1 - 4.3e-05 23.3 0.1 0.00024 20.9 0.1 2.4 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase OCD_Mu_crystall PF02423.15 CCU99498.1 - 0.0054 15.7 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family AAA_33 PF13671.6 CCU99498.1 - 0.0058 16.8 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCU99498.1 - 0.042 14.2 0.3 0.36 11.2 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 CCU99498.1 - 0.048 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dus PF01207.17 CCU99499.1 - 8.2e-44 149.9 0.1 8.5e-43 146.6 0.0 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) SNRNP27 PF08648.12 CCU99499.1 - 2e-19 69.4 0.2 9.6e-19 67.2 0.5 1.9 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins HMGL-like PF00682.19 CCU99500.1 - 5.5e-80 268.7 1.0 5.5e-80 268.7 1.0 1.5 2 0 0 2 2 2 1 HMGL-like FliG_N PF14842.6 CCU99500.1 - 0.064 13.8 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 FliG N-terminal domain Transp_cyt_pur PF02133.15 CCU99501.1 - 3.2e-32 111.9 39.4 3e-31 108.7 39.4 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin B12D PF06522.11 CCU99501.1 - 0.15 11.9 0.2 0.81 9.5 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit CLASP_N PF12348.8 CCU99502.1 - 8.8e-17 61.4 0.0 7.1e-06 25.8 0.0 5.1 5 0 0 5 5 5 3 CLASP N terminal HEAT PF02985.22 CCU99502.1 - 3.9e-12 45.3 24.8 0.031 14.5 0.0 11.2 10 0 0 10 10 9 4 HEAT repeat HEAT_2 PF13646.6 CCU99502.1 - 1.5e-09 38.1 29.4 0.0009 19.6 3.5 9.4 6 3 3 9 9 9 3 HEAT repeats Cnd1 PF12717.7 CCU99502.1 - 5.3e-06 26.6 0.2 0.44 10.6 0.0 5.7 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 CCU99502.1 - 0.00032 20.9 1.1 0.44 10.9 0.0 3.4 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 CCU99502.1 - 0.0055 15.3 1.6 7.1 5.1 0.0 4.1 4 0 0 4 4 4 2 Adaptin N terminal region VHS PF00790.19 CCU99502.1 - 0.047 13.6 0.4 1.4 8.7 0.0 3.0 3 0 0 3 3 3 0 VHS domain TAN PF11640.8 CCU99502.1 - 0.071 13.2 6.2 3.2 7.9 0.0 5.4 6 0 0 6 6 6 0 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.6 CCU99502.1 - 0.48 11.0 31.5 5.1 7.7 0.1 9.1 8 1 1 9 9 9 0 HEAT-like repeat Proteasom_PSMB PF10508.9 CCU99502.1 - 1.2 7.6 4.6 1 7.8 0.1 3.0 4 0 0 4 4 4 0 Proteasome non-ATPase 26S subunit Tti2 PF10521.9 CCU99502.1 - 1.3 8.5 4.3 1.2 8.6 0.0 3.2 4 0 0 4 4 4 0 Tti2 family Cyto_heme_lyase PF01265.17 CCU99504.1 - 3.4e-69 233.6 16.9 3.3e-56 191.0 10.2 3.6 1 1 2 3 3 3 2 Cytochrome c/c1 heme lyase Pkinase PF00069.25 CCU99504.1 - 5e-08 32.6 0.0 6.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99504.1 - 0.086 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 CCU99505.1 - 2.5e-43 148.3 0.0 3.3e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99505.1 - 7.1e-27 94.3 0.0 8.9e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCU99505.1 - 4.8e-06 25.6 0.1 1.2e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CCU99505.1 - 0.002 18.1 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 CCU99505.1 - 0.003 17.2 0.0 0.04 13.5 0.0 2.1 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 CCU99505.1 - 0.0039 16.7 0.0 0.0068 15.9 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 CCU99505.1 - 0.0048 16.3 0.0 0.01 15.2 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CCU99505.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 CDC37_C PF08564.10 CCU99505.1 - 0.043 13.9 0.1 0.093 12.9 0.1 1.5 1 0 0 1 1 1 0 Cdc37 C terminal domain Kinase-like PF14531.6 CCU99505.1 - 0.058 12.7 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Snf7 PF03357.21 CCU99506.1 - 3.1e-30 105.1 21.6 7.1e-30 103.9 21.7 1.5 1 1 0 1 1 1 1 Snf7 TPR_MLP1_2 PF07926.12 CCU99506.1 - 0.057 13.5 9.5 0.084 12.9 9.5 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HTH_6 PF01418.17 CCU99506.1 - 0.06 13.3 0.3 0.06 13.3 0.3 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family NUDIX PF00293.28 CCU99506.1 - 0.069 13.2 0.1 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 NUDIX domain Nsp1_C PF05064.13 CCU99506.1 - 0.16 11.7 3.7 0.18 11.6 0.4 2.3 2 1 0 2 2 2 0 Nsp1-like C-terminal region Exonuc_VII_L PF02601.15 CCU99506.1 - 0.7 9.4 8.6 0.94 9.0 8.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit YlqD PF11068.8 CCU99506.1 - 1.3 9.4 14.2 4.6 7.6 10.5 2.2 1 1 1 2 2 2 0 YlqD protein COG2 PF06148.11 CCU99506.1 - 3.4 7.8 10.3 10 6.2 1.2 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PRKG1_interact PF15898.5 CCU99506.1 - 5.4 8.0 14.1 4.3 8.3 8.6 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 CCU99506.1 - 7.2 7.1 12.3 1.6 9.2 7.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region CLN3 PF02487.17 CCU99507.1 - 1.5e-77 261.4 4.5 3e-77 260.4 4.5 1.4 1 1 0 1 1 1 1 CLN3 protein DUF1656 PF07869.12 CCU99507.1 - 1.2 9.2 6.6 5.6 7.1 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) ADK PF00406.22 CCU99508.1 - 8.2e-43 146.1 0.0 3.3e-42 144.1 0.0 1.8 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CCU99508.1 - 9.5e-34 116.7 0.0 1.4e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCU99508.1 - 8.7e-12 45.7 0.0 1.4e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CCU99508.1 - 3.9e-07 29.9 0.1 0.00085 19.1 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 CCU99508.1 - 0.0001 22.5 0.1 0.019 15.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain dNK PF01712.19 CCU99508.1 - 0.0014 18.5 0.1 0.0063 16.4 0.1 1.8 2 0 0 2 2 2 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 CCU99508.1 - 0.043 13.1 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 CCU99508.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 DUF1754 PF08555.10 CCU99509.1 - 0.00028 21.6 10.8 0.0016 19.2 7.0 2.4 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF4315 PF14193.6 CCU99509.1 - 0.029 14.4 0.8 0.048 13.7 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) PAPA-1 PF04795.12 CCU99509.1 - 0.13 13.1 4.7 0.17 12.7 1.8 2.0 2 0 0 2 2 2 0 PAPA-1-like conserved region ATP-synt_D PF01813.17 CCU99510.1 - 9.4e-46 156.1 2.4 4.9e-45 153.8 2.4 1.8 1 1 0 1 1 1 1 ATP synthase subunit D DUF1640 PF07798.11 CCU99510.1 - 0.034 14.2 0.4 0.05 13.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FH2 PF02181.23 CCU99511.1 - 7.6e-69 232.6 2.9 7.6e-69 232.6 2.9 2.3 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CCU99511.1 - 6.3e-42 143.4 0.5 6.3e-42 143.4 0.5 2.6 2 1 1 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 CCU99511.1 - 1.5e-12 47.5 0.2 2.9e-05 23.7 0.0 3.2 2 1 1 3 3 3 2 Diaphanous GTPase-binding Domain Sec16_C PF12931.7 CCU99513.1 - 1.5e-75 254.6 0.1 1.9e-75 254.3 0.1 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 TPR_14 PF13428.6 CCU99513.1 - 0.15 13.0 0.6 12 7.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.27 CCU99514.1 - 3.5e-34 118.3 0.0 1.1e-33 116.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CCU99514.1 - 7.1e-08 32.1 0.0 0.00026 20.5 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CCU99514.1 - 4.6e-05 23.9 0.0 0.00011 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CCU99514.1 - 7.5e-05 23.2 0.1 0.24 11.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 CCU99514.1 - 0.0013 18.6 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CCU99514.1 - 0.0014 18.7 0.0 0.0085 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCU99514.1 - 0.002 18.4 0.1 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CCU99514.1 - 0.0027 17.7 0.0 0.087 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CCU99514.1 - 0.0057 16.5 0.0 0.014 15.2 0.0 1.7 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCU99514.1 - 0.0059 16.3 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCU99514.1 - 0.0072 16.2 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Rad17 PF03215.15 CCU99514.1 - 0.0087 16.0 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain G-alpha PF00503.20 CCU99514.1 - 0.024 13.8 0.0 0.045 12.9 0.0 1.6 1 1 0 1 1 1 0 G-protein alpha subunit ATP-synt_ab PF00006.25 CCU99514.1 - 0.026 14.2 0.0 0.038 13.7 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 CCU99514.1 - 0.063 13.4 0.0 0.25 11.4 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 CCU99514.1 - 0.08 13.2 0.2 0.74 10.1 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 CCU99514.1 - 0.095 13.2 1.5 0.11 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CCU99514.1 - 0.2 11.2 0.5 0.82 9.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain TP6A_N PF04406.14 CCU99515.1 - 9.3e-18 64.0 0.0 1.8e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase WD40 PF00400.32 CCU99516.1 - 0.0023 18.7 0.5 0.035 15.0 0.2 2.6 2 1 0 2 2 2 1 WD domain, G-beta repeat Topoisom_bac PF01131.20 CCU99517.1 - 3.4e-93 312.9 0.5 4.7e-93 312.4 0.5 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 CCU99517.1 - 0.0024 17.9 1.4 0.0078 16.3 1.4 2.0 1 0 0 1 1 1 1 GRF zinc finger HAMP PF00672.25 CCU99518.1 - 1.5e-38 131.0 20.6 7.6e-08 32.6 0.1 9.2 7 2 1 8 8 8 6 HAMP domain HATPase_c PF02518.26 CCU99518.1 - 4.5e-27 94.8 0.0 2.5e-26 92.4 0.0 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CCU99518.1 - 5.5e-17 62.0 0.5 4.5e-15 55.8 0.3 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 CCU99518.1 - 7.9e-17 61.1 1.3 1.4e-15 57.1 0.3 3.9 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain APG17 PF04108.12 CCU99518.1 - 4.6e-07 29.3 0.0 0.089 11.9 1.6 3.8 2 1 2 4 4 4 2 Autophagy protein Apg17 Baculo_PEP_C PF04513.12 CCU99518.1 - 2e-06 27.9 26.7 0.34 11.0 0.0 7.2 2 1 4 7 7 7 4 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1843 PF08898.10 CCU99518.1 - 0.00097 19.6 0.7 27 5.4 0.1 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) TMF_TATA_bd PF12325.8 CCU99518.1 - 0.018 15.2 4.2 6.7 7.0 0.0 4.1 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding PhoR PF11808.8 CCU99518.1 - 0.023 15.1 0.0 43 4.6 0.0 4.0 4 0 0 4 4 4 0 Phosphate regulon sensor protein PhoR Rab5-bind PF09311.11 CCU99518.1 - 0.3 10.4 14.3 6.4 6.1 0.1 5.4 2 2 3 5 5 5 0 Rabaptin-like protein SpoIIID PF12116.8 CCU99518.1 - 0.37 10.9 3.9 57 3.9 0.0 4.9 6 0 0 6 6 6 0 Stage III sporulation protein D DUF3150 PF11348.8 CCU99518.1 - 0.51 9.5 3.2 1.1 8.4 0.1 3.1 3 1 0 4 4 4 0 Protein of unknown function (DUF3150) DUF3829 PF12889.7 CCU99518.1 - 0.73 9.3 3.9 4.3 6.7 0.0 3.5 3 2 2 6 6 6 0 Protein of unknown function (DUF3829) Thioredoxin_10 PF17991.1 CCU99518.1 - 1.5 9.3 4.4 9.3 6.8 0.2 2.9 2 1 1 3 3 3 0 Thioredoxin like C-terminal domain TFIIS_M PF07500.14 CCU99519.1 - 6.6e-23 81.3 0.0 1.1e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 CCU99519.1 - 2.3e-11 43.8 0.0 5.6e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 CCU99519.1 - 7.6e-10 38.5 10.4 1.3e-09 37.8 10.4 1.4 1 0 0 1 1 1 1 PHD-finger BUD22 PF09073.10 CCU99519.1 - 0.0044 16.4 12.9 0.0091 15.4 12.9 1.4 1 0 0 1 1 1 1 BUD22 PHD_2 PF13831.6 CCU99519.1 - 0.15 11.6 4.7 0.28 10.7 4.7 1.5 1 0 0 1 1 1 0 PHD-finger SDA1 PF05285.12 CCU99519.1 - 0.22 10.9 9.0 0.4 10.0 9.0 1.3 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 CCU99519.1 - 0.59 9.8 11.5 1.4 8.6 5.4 2.4 2 0 0 2 2 2 0 FAM176 family MBOAT_2 PF13813.6 CCU99521.1 - 4.1e-09 36.6 1.8 4.1e-09 36.6 1.8 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family WD40 PF00400.32 CCU99522.1 - 0.0026 18.6 0.0 0.03 15.2 0.0 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat Histone PF00125.24 CCU99523.1 - 4.5e-19 69.1 0.0 5.6e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CCU99523.1 - 4.7e-12 45.4 1.2 5.3e-12 45.3 0.1 1.6 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CCU99523.1 - 0.028 14.7 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.25 CCU99524.1 - 1.2e-63 215.0 0.0 1.5e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99524.1 - 8.6e-42 143.2 0.0 1.1e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU99524.1 - 6.5e-08 32.2 0.0 9.8e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCU99524.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCU99524.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCU99524.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CCU99524.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 CCU99524.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CCU99524.1 - 0.28 10.2 0.0 0.42 9.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 NFACT-R_1 PF05670.13 CCU99525.1 - 3.3e-41 140.3 0.1 6.4e-41 139.4 0.1 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain Glycos_transf_2 PF00535.26 CCU99526.1 - 3.4e-21 75.8 0.0 6.1e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CCU99526.1 - 6.9e-07 29.4 0.0 0.00016 21.6 0.0 2.4 2 1 0 2 2 2 2 Glycosyltransferase like family 2 SID-1_RNA_chan PF13965.6 CCU99526.1 - 0.04 12.3 0.0 0.055 11.9 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4027 PF13219.6 CCU99526.1 - 1 9.3 3.4 1.4 8.8 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4027) Sin3a_C PF16879.5 CCU99527.1 - 1.1e-62 212.3 0.0 2.2e-62 211.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 CCU99527.1 - 4.1e-40 135.8 0.1 8.4e-40 134.8 0.1 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 CCU99527.1 - 3.6e-36 123.0 9.2 2.3e-15 56.4 4.9 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat eIF-1a PF01176.19 CCU99528.1 - 1.7e-20 72.5 0.0 2.5e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 YIF1 PF03878.15 CCU99529.1 - 3.9e-89 298.3 0.0 6.7e-89 297.5 0.0 1.3 1 1 0 1 1 1 1 YIF1 RNA_pol_Rpb2_6 PF00562.28 CCU99530.1 - 5.6e-108 361.5 0.0 1e-107 360.6 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CCU99530.1 - 9.2e-35 120.0 0.0 1.5e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CCU99530.1 - 1.9e-27 95.2 0.0 4.2e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CCU99530.1 - 5.6e-22 77.5 0.0 1.1e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 CCU99530.1 - 6e-21 74.9 0.0 8.8e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CCU99530.1 - 8.5e-18 64.5 0.0 7e-16 58.4 0.0 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Nfu_N PF08712.11 CCU99531.1 - 2e-30 104.7 0.0 5.1e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 CCU99531.1 - 4e-20 71.7 0.2 9.8e-20 70.5 0.1 1.6 1 1 1 2 2 2 1 NifU-like domain YojJ PF10372.9 CCU99531.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Peptidase_S10 PF00450.22 CCU99533.1 - 6e-92 309.2 0.0 6.8e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 CCU99533.1 - 0.033 13.4 0.1 7.7 5.7 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 NOC3p PF07540.11 CCU99534.1 - 6.9e-28 97.0 0.0 1.7e-27 95.7 0.0 1.7 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 CCU99534.1 - 3e-13 50.1 5.5 6.3e-13 49.1 0.1 3.0 3 0 0 3 3 3 1 CBF/Mak21 family RRM_1 PF00076.22 CCU99535.1 - 5.2e-82 269.7 2.2 2.3e-20 72.2 0.3 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CCU99535.1 - 9.7e-28 96.2 0.7 3e-26 91.4 0.4 2.7 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CCU99535.1 - 4.6e-11 42.4 0.1 0.084 12.5 0.0 4.2 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCU99535.1 - 4.4e-06 26.5 0.0 0.00064 19.5 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CCU99535.1 - 0.0037 17.2 1.3 31 4.7 0.0 4.0 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CCU99535.1 - 0.0039 17.3 0.1 9.1 6.5 0.0 4.7 4 2 0 4 4 4 1 RNA recognition motif DbpA PF03880.15 CCU99535.1 - 0.17 11.9 0.0 22 5.1 0.0 3.6 4 0 0 4 4 4 0 DbpA RNA binding domain GrpE PF01025.19 CCU99536.1 - 8.7e-45 152.4 0.1 1.1e-44 152.1 0.1 1.0 1 0 0 1 1 1 1 GrpE DUF3037 PF11236.8 CCU99536.1 - 0.013 15.9 0.4 0.21 12.0 0.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3037) DUF4201 PF13870.6 CCU99536.1 - 0.037 13.8 2.9 0.052 13.3 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Cauli_DNA-bind PF03310.13 CCU99536.1 - 0.067 13.3 0.5 0.16 12.1 0.5 1.6 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein TB2_DP1_HVA22 PF03134.19 CCU99537.1 - 4e-29 100.4 9.7 4e-29 100.4 9.7 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family KH_8 PF17903.1 CCU99538.1 - 0.00015 21.8 0.0 0.00025 21.1 0.0 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CCU99538.1 - 0.016 15.0 0.4 0.033 14.0 0.4 1.5 1 0 0 1 1 1 0 KH domain MitMem_reg PF13012.6 CCU99539.1 - 2.2e-33 115.0 0.2 3.4e-33 114.4 0.2 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CCU99539.1 - 6.6e-30 103.5 0.0 1.3e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RIBIOP_C PF04950.12 CCU99541.1 - 1.9e-103 345.9 0.1 7.3e-103 344.0 0.0 1.8 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CCU99541.1 - 2.5e-18 65.9 0.0 1e-17 64.0 0.0 2.0 2 0 0 2 2 2 1 AARP2CN (NUC121) domain DUF3793 PF12672.7 CCU99541.1 - 0.22 11.5 0.1 0.45 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Drc1-Sld2 PF11719.8 CCU99541.1 - 4.9 6.6 21.4 4.3 6.8 19.3 2.0 2 0 0 2 2 2 0 DNA replication and checkpoint protein ORMDL PF04061.14 CCU99542.1 - 9.7e-47 158.2 6.4 3.6e-46 156.4 6.4 1.7 1 1 0 1 1 1 1 ORMDL family DUF1801 PF08818.11 CCU99542.1 - 0.046 14.2 0.0 0.089 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DU1801) LNS2 PF08235.13 CCU99544.1 - 1.1e-100 335.7 0.0 1.6e-100 335.3 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CCU99544.1 - 2.3e-29 101.4 0.1 4.5e-28 97.2 0.1 2.5 2 1 0 2 2 2 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 CCU99544.1 - 2.9e-05 24.1 0.0 6.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain HAD PF12710.7 CCU99544.1 - 0.088 13.2 0.8 5.7 7.3 0.1 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 CCU99544.1 - 0.12 11.9 0.0 0.9 9.1 0.0 2.0 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) HAT_KAT11 PF08214.11 CCU99545.1 - 6.6e-44 150.6 0.0 8.9e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein FKBP_C PF00254.28 CCU99546.1 - 2.6e-30 104.6 0.0 2.9e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RCC1 PF00415.18 CCU99547.1 - 6.1e-57 190.0 3.5 3.7e-11 43.5 0.0 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CCU99547.1 - 4.1e-37 125.2 29.9 5.4e-09 35.6 0.1 7.8 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 CCU99547.1 - 0.18 11.5 0.0 4 7.1 0.0 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split Linker_histone PF00538.19 CCU99548.1 - 9.2e-20 70.8 0.0 9.2e-20 70.8 0.0 2.7 2 1 1 3 3 3 1 linker histone H1 and H5 family SRP-alpha_N PF04086.13 CCU99548.1 - 3.9 7.3 26.5 5.8 6.8 26.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal tRNA-synt_1 PF00133.22 CCU99549.1 - 1.6e-209 697.1 0.0 1.6e-208 693.9 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CCU99549.1 - 2.8e-35 121.5 0.0 4.9e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CCU99549.1 - 3.2e-13 49.2 0.1 1.3e-06 27.4 0.1 4.0 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CCU99549.1 - 4.1e-10 39.5 0.1 1.8e-06 27.6 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 CCU99549.1 - 0.0006 19.3 0.0 0.58 9.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 CCU99549.1 - 0.17 11.2 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Val_tRNA-synt_C PF10458.9 CCU99549.1 - 3.8 7.9 8.7 0.092 13.0 1.1 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm IKI3 PF04762.12 CCU99550.1 - 1.2e-210 702.0 0.0 1.7e-210 701.5 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 CCU99550.1 - 0.02 15.2 0.1 4.7 7.6 0.1 4.0 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Se-cys_synth_N PF12390.8 CCU99550.1 - 0.02 15.1 0.2 0.02 15.1 0.2 3.9 4 0 0 4 4 4 0 Selenocysteine synthase N terminal MFS_1 PF07690.16 CCU99552.1 - 2.2e-41 141.9 27.4 2.2e-41 141.9 27.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCU99552.1 - 3.5e-12 46.0 21.4 7.8e-12 44.8 21.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter ECH_1 PF00378.20 CCU99552.1 - 2e-07 30.6 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CCU99552.1 - 0.031 13.8 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ABC1 PF03109.16 CCU99553.1 - 5.8e-30 103.9 0.0 1.1e-29 103.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 CCU99553.1 - 0.0037 16.7 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Spindle_Spc25 PF08234.12 CCU99554.1 - 1.3e-18 67.0 0.0 3e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 SKA2 PF16740.5 CCU99554.1 - 0.00031 20.5 11.7 0.0017 18.1 6.7 2.4 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 JAKMIP_CC3 PF16034.5 CCU99554.1 - 0.00039 20.4 9.4 0.00055 19.9 9.4 1.1 1 0 0 1 1 1 1 JAKMIP CC3 domain TolA_bind_tri PF16331.5 CCU99554.1 - 0.0037 17.3 13.4 0.11 12.6 8.1 2.6 1 1 1 2 2 2 2 TolA binding protein trimerisation Golgin_A5 PF09787.9 CCU99554.1 - 0.011 15.2 9.8 0.015 14.8 9.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 ERM PF00769.19 CCU99554.1 - 0.013 15.3 14.2 0.018 14.9 14.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HAUS-augmin3 PF14932.6 CCU99554.1 - 0.015 14.9 14.2 0.018 14.6 13.7 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.19 CCU99554.1 - 0.029 12.3 3.1 0.039 11.9 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HIP1_clath_bdg PF16515.5 CCU99554.1 - 0.033 14.8 17.4 0.3 11.7 3.8 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FAM184 PF15665.5 CCU99554.1 - 0.037 13.8 12.8 0.064 13.0 12.8 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HMMR_N PF15905.5 CCU99554.1 - 0.093 12.2 9.7 0.13 11.7 9.7 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 CCU99554.1 - 0.27 11.7 17.1 0.36 11.3 15.9 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1640 PF07798.11 CCU99554.1 - 0.33 11.0 8.0 1.2 9.1 7.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) ADIP PF11559.8 CCU99554.1 - 0.36 10.9 14.1 0.72 9.9 14.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 CCU99554.1 - 0.54 9.1 13.1 0.83 8.5 13.1 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 CCU99554.1 - 0.73 10.0 15.1 1.1 9.5 15.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 CCU99554.1 - 0.8 10.0 9.0 2.7 8.2 8.1 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMCO5 PF14992.6 CCU99554.1 - 0.81 9.2 6.7 1.1 8.7 6.7 1.2 1 0 0 1 1 1 0 TMCO5 family DUF4407 PF14362.6 CCU99554.1 - 0.93 8.8 10.4 1.3 8.3 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mod_r PF07200.13 CCU99554.1 - 1.2 9.3 11.7 1.7 8.7 7.7 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein UPF0242 PF06785.11 CCU99554.1 - 2 8.5 9.8 2.7 8.1 9.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 CCU99554.1 - 2.9 8.6 7.3 13 6.5 6.5 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Swi5 PF07061.11 CCU99554.1 - 2.9 8.1 7.9 5.2 7.2 0.9 2.8 1 1 2 3 3 3 0 Swi5 5_nucleotid PF05761.14 CCU99554.1 - 2.9 6.7 7.6 4 6.2 7.6 1.1 1 0 0 1 1 1 0 5' nucleotidase family CENP-H PF05837.12 CCU99554.1 - 3.2 8.2 16.0 2.5 8.6 11.4 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 CCU99554.1 - 3.9 7.5 7.3 2.1 8.4 1.1 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 CCU99554.1 - 4.4 7.8 14.3 2.5 8.6 7.0 2.6 1 1 1 2 2 2 0 Cell division protein ZapB HALZ PF02183.18 CCU99554.1 - 4.5 7.6 6.5 0.61 10.3 0.2 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper Pkinase PF00069.25 CCU99555.1 - 1.2e-60 205.2 0.0 5.2e-60 203.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99555.1 - 3.3e-27 95.4 0.0 1.1e-18 67.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCU99555.1 - 0.0002 20.7 0.1 0.013 14.8 0.0 2.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CCU99555.1 - 0.003 17.5 0.7 0.19 11.6 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CCU99555.1 - 0.0074 15.7 0.1 0.019 14.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CCU99555.1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain MAPEG PF01124.18 CCU99556.1 - 1.4e-21 76.8 6.8 1.6e-21 76.6 6.8 1.0 1 0 0 1 1 1 1 MAPEG family HECT PF00632.25 CCU99557.1 - 1.2e-98 330.4 0.0 1.5e-98 330.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-UBR PF02207.20 CCU99558.1 - 3.7e-14 52.6 17.1 3.7e-14 52.6 17.1 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CCU99558.1 - 1.2e-06 28.2 0.0 3.4e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-ribbon_3 PF13248.6 CCU99558.1 - 0.024 14.0 2.5 0.037 13.5 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TRAPP PF04051.16 CCU99559.1 - 4e-23 81.7 0.0 5.7e-23 81.3 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Bromodomain PF00439.25 CCU99560.1 - 3.8e-32 110.2 0.2 5.8e-16 58.3 0.0 3.1 2 1 0 2 2 2 2 Bromodomain BET PF17035.5 CCU99560.1 - 3.9e-20 71.8 0.7 1.2e-19 70.2 0.7 1.9 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF3829 PF12889.7 CCU99560.1 - 0.092 12.2 2.2 0.21 11.0 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) PilJ PF13675.6 CCU99560.1 - 0.11 12.5 0.6 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Abhydro_lipase PF04083.16 CCU99562.1 - 1.9e-13 49.8 0.0 4.6e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CCU99562.1 - 3.9e-10 39.8 0.1 8.6e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCU99562.1 - 3e-05 23.4 0.0 5.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PUF PF00806.19 CCU99563.1 - 1e-64 210.7 11.2 1.4e-08 33.9 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RFC1 PF08519.12 CCU99564.1 - 8.1e-49 165.8 0.0 1.5e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 CCU99564.1 - 1.9e-09 37.7 0.0 3.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 CCU99564.1 - 3.2e-08 33.7 0.1 8.1e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 CCU99564.1 - 1e-07 32.4 0.0 2.9e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CCU99564.1 - 0.00039 20.5 0.0 0.029 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCU99564.1 - 0.00074 19.9 1.1 0.0042 17.5 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 CCU99564.1 - 0.0072 16.5 0.0 0.034 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 CCU99564.1 - 0.057 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 CCU99564.1 - 0.073 12.8 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain SAGA-Tad1 PF12767.7 CCU99564.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.8 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AAA_22 PF13401.6 CCU99564.1 - 0.085 13.1 0.1 0.86 9.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 CCU99564.1 - 0.09 12.5 0.3 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III, delta subunit 5_3_exonuc PF01367.20 CCU99564.1 - 0.19 12.3 1.0 3.4 8.3 0.0 3.1 3 1 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Rgp1 PF08737.10 CCU99565.1 - 1.3e-71 242.0 0.0 5.7e-40 137.8 0.0 2.1 1 1 1 2 2 2 2 Rgp1 Arrestin_C PF02752.22 CCU99565.1 - 4.5e-05 23.9 0.0 0.39 11.2 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCU99565.1 - 0.0031 17.6 0.0 0.0089 16.1 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Prophage_tail PF06605.11 CCU99565.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Prophage endopeptidase tail Sec20 PF03908.13 CCU99566.1 - 1.2e-17 63.6 1.0 2.5e-17 62.6 1.0 1.5 1 0 0 1 1 1 1 Sec20 adh_short PF00106.25 CCU99567.1 - 1.7e-27 96.2 0.1 2.3e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCU99567.1 - 8.6e-21 74.6 0.1 1.3e-20 74.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCU99567.1 - 3.6e-06 27.0 0.1 7.7e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 KR domain Arm PF00514.23 CCU99568.1 - 5.3e-75 245.4 27.3 8.9e-12 44.6 0.1 11.5 11 1 1 12 12 12 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CCU99568.1 - 2.6e-16 59.7 18.9 0.0081 16.7 0.2 9.1 6 2 3 9 9 9 5 HEAT-like repeat HEAT_2 PF13646.6 CCU99568.1 - 5.1e-14 52.4 13.7 0.00027 21.3 0.1 7.3 4 2 3 7 7 6 4 HEAT repeats Adaptin_N PF01602.20 CCU99568.1 - 1.1e-10 40.7 7.8 2.1e-07 29.9 1.0 2.6 1 1 1 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 CCU99568.1 - 5.5e-10 38.6 23.7 0.84 10.1 0.0 9.9 11 0 0 11 11 10 5 HEAT repeat Arm_2 PF04826.13 CCU99568.1 - 1.2e-09 38.0 8.2 3.2e-06 26.8 3.2 3.2 2 1 2 4 4 4 2 Armadillo-like KAP PF05804.12 CCU99568.1 - 6.8e-08 31.1 0.2 1.4e-07 30.1 0.1 1.4 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 CCU99568.1 - 4.1e-06 26.3 6.5 0.0068 15.7 0.6 4.3 1 1 1 3 3 3 2 V-ATPase subunit H DUF3361 PF11841.8 CCU99568.1 - 0.00011 22.2 9.2 0.021 14.8 0.1 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3361) Cnd1 PF12717.7 CCU99568.1 - 0.00018 21.6 6.8 0.021 14.9 0.5 4.2 1 1 4 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 CCU99568.1 - 0.0015 18.0 7.0 1.9 7.9 1.2 4.5 2 1 2 4 4 4 2 Family of unknown function (DUF5578) UNC45-central PF11701.8 CCU99568.1 - 0.0077 16.2 4.2 1.8 8.5 0.1 4.0 3 1 1 4 4 4 1 Myosin-binding striated muscle assembly central V-ATPase_H_C PF11698.8 CCU99568.1 - 0.012 15.7 2.6 40 4.3 0.1 4.4 3 1 3 6 6 6 0 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 CCU99568.1 - 0.064 13.9 0.0 5.7 7.6 0.0 2.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region YqfD PF06898.11 CCU99568.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD HEAT_PBS PF03130.16 CCU99568.1 - 0.25 12.1 12.8 21 6.1 0.1 7.5 9 0 0 9 9 7 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 CCU99568.1 - 0.64 10.1 4.5 3.6 7.7 0.0 3.9 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain FF PF01846.19 CCU99569.1 - 3e-20 72.1 6.3 7.7e-08 32.4 0.0 6.4 5 1 0 5 5 5 3 FF domain RhoGAP-FF1 PF16512.5 CCU99569.1 - 1.3e-06 29.0 1.1 1.3e-06 29.0 1.1 3.9 4 2 0 4 4 4 1 p190-A and -B Rho GAPs FF domain WW PF00397.26 CCU99569.1 - 1.2 9.3 4.4 0.17 12.0 0.3 1.8 2 0 0 2 2 2 0 WW domain Abhydrolase_1 PF00561.20 CCU99570.1 - 3e-26 92.6 0.0 1.7e-25 90.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 CCU99570.1 - 0.096 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein TIP120 PF08623.10 CCU99571.1 - 5e-35 120.7 0.2 8.7e-34 116.7 0.0 2.8 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) RTP1_C1 PF10363.9 CCU99571.1 - 4.9e-05 23.5 9.8 5.5 7.2 0.1 6.8 5 2 1 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 CCU99571.1 - 0.0008 19.5 0.2 0.0008 19.5 0.2 11.2 11 1 1 12 12 12 2 HEAT repeat HEAT_2 PF13646.6 CCU99571.1 - 0.0016 18.8 0.5 0.0016 18.8 0.5 10.0 7 4 2 10 10 10 4 HEAT repeats Adaptin_N PF01602.20 CCU99571.1 - 0.0088 14.6 12.0 2.5 6.6 0.0 5.0 5 1 0 5 5 5 3 Adaptin N terminal region HEAT_EZ PF13513.6 CCU99571.1 - 0.012 16.2 0.9 0.012 16.2 0.9 11.5 11 3 2 13 13 13 0 HEAT-like repeat Cnd1 PF12717.7 CCU99571.1 - 0.013 15.5 7.0 0.41 10.7 0.0 4.7 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CCU99571.1 - 0.29 10.7 7.2 13 5.3 0.0 4.6 4 1 1 5 5 5 0 CLASP N terminal PQQ_2 PF13360.6 CCU99572.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain McyA_C PF12593.8 CCU99572.1 - 0.07 12.9 0.5 0.47 10.3 0.0 2.6 3 0 0 3 3 3 0 Microcystin synthetase C terminal Lipase_3 PF01764.25 CCU99573.1 - 1.1e-26 93.4 0.0 1.5e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CCU99573.1 - 0.044 13.3 0.0 0.078 12.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 CCU99573.1 - 0.045 13.0 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 CCU99574.1 - 5.2e-19 68.4 25.8 6.6e-19 68.0 25.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CCU99574.1 - 0.0006 19.2 11.7 0.0006 19.2 11.7 2.3 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF2964 PF11177.8 CCU99574.1 - 0.24 11.6 7.3 0.11 12.7 1.1 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF2964) LIP PF03583.14 CCU99575.1 - 2e-56 191.4 0.0 2.9e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Branch_AA_trans PF05525.13 CCU99575.1 - 0.058 12.3 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport protein MFS_1 PF07690.16 CCU99576.1 - 1e-44 153.0 21.7 1.4e-44 152.5 21.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCU99576.1 - 3.2e-16 59.2 6.5 3.2e-16 59.2 6.5 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 CCU99576.1 - 8e-07 28.2 7.1 8e-07 28.2 7.1 2.5 3 1 0 3 3 3 1 MFS_1 like family TRI12 PF06609.13 CCU99576.1 - 0.0005 18.6 3.4 0.00072 18.1 3.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 CCU99576.1 - 0.11 10.9 5.8 0.19 10.1 5.8 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector OATP PF03137.20 CCU99576.1 - 0.18 10.1 5.5 0.037 12.3 0.3 2.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CCU99577.1 - 7.2e-53 179.8 24.9 3.2e-52 177.6 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCU99577.1 - 1.7e-13 50.3 23.2 5.9e-13 48.5 8.5 3.5 3 1 1 4 4 4 3 Sugar (and other) transporter TRI12 PF06609.13 CCU99577.1 - 9e-07 27.7 2.3 1.4e-06 27.0 2.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CCU99577.1 - 0.00013 20.4 0.9 0.00013 20.4 0.9 2.8 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 CCU99577.1 - 0.29 9.9 20.5 0.041 12.7 8.4 3.7 3 1 0 3 3 3 0 MFS_1 like family Transgly_assoc PF04226.13 CCU99577.1 - 4.8 7.5 8.5 70 3.8 5.0 2.9 2 0 0 2 2 2 0 Transglycosylase associated protein Peptidase_M3 PF01432.20 CCU99579.1 - 2.5e-125 419.4 0.0 3e-125 419.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 tRNA-synt_2d PF01409.20 CCU99580.1 - 4.2e-84 281.9 0.0 5.6e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 CCU99580.1 - 4.3e-07 29.6 0.0 0.0016 17.9 0.0 2.5 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD3 PF18553.1 CCU99580.1 - 1.5e-06 28.4 0.7 1.8e-05 24.9 0.0 3.0 4 0 0 4 4 4 1 PheRS DNA binding domain 3 tRNA-synt_2 PF00152.20 CCU99580.1 - 0.0013 17.9 0.1 0.0085 15.2 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 CCU99580.1 - 0.012 15.6 0.3 0.064 13.3 0.3 2.1 1 1 0 1 1 1 0 PheRS DNA binding domain 2 RFX1_trans_act PF04589.13 CCU99580.1 - 0.066 13.4 1.9 0.11 12.7 1.9 1.3 1 0 0 1 1 1 0 RFX1 transcription activation region tRNA-synt_2b PF00587.25 CCU99580.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) WD40 PF00400.32 CCU99581.1 - 3.6e-37 125.7 15.5 2.4e-07 31.3 0.0 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 CCU99581.1 - 5.1e-11 41.9 4.2 1e-10 41.0 4.2 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 CCU99581.1 - 1.1e-10 41.7 0.0 0.02 15.2 0.0 5.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCU99581.1 - 0.0016 17.1 0.1 0.037 12.7 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 CCU99581.1 - 0.0067 15.8 0.0 7.9 5.7 0.0 2.9 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 CCU99581.1 - 0.03 13.3 0.0 52 2.6 0.0 3.8 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L24e PF01246.20 CCU99582.1 - 3.5e-32 110.4 6.5 5.9e-32 109.7 6.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L24e HAGH_C PF16123.5 CCU99582.1 - 0.016 15.7 1.5 0.03 14.9 1.5 1.6 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus R2K_3 PF14243.6 CCU99582.1 - 0.079 13.0 0.7 0.09 12.8 0.7 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 SRP9-21 PF05486.12 CCU99583.1 - 7.5e-06 26.3 1.0 0.00048 20.5 1.0 2.2 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) CTD_bind PF04818.13 CCU99584.1 - 2.1e-05 25.2 0.0 9.2e-05 23.2 0.0 2.1 2 1 0 2 2 2 1 RNA polymerase II-binding domain. Mus7 PF09462.10 CCU99585.1 - 1e-74 252.6 0.0 2e-74 251.6 0.0 1.5 2 0 0 2 2 2 1 Mus7/MMS22 family RhoGEF PF00621.20 CCU99585.1 - 3.8e-32 112.0 0.5 1.9e-30 106.5 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 CCU99585.1 - 5.1e-16 58.6 10.4 9.8e-16 57.7 10.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_UBOX PF13445.6 CCU99585.1 - 0.033 14.2 4.4 0.082 12.9 4.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CCU99585.1 - 0.096 12.7 10.3 0.2 11.6 10.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 CCU99585.1 - 1.4 9.3 9.4 3.9 7.9 9.4 1.9 1 0 0 1 1 1 0 Ring finger domain zf-CRD PF17979.1 CCU99585.1 - 3.4 7.8 6.1 7.5 6.6 6.1 1.5 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions FYVE_2 PF02318.16 CCU99585.1 - 5.1 7.4 5.3 10 6.4 5.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger FA_desaturase PF00487.24 CCU99586.1 - 2e-27 96.7 26.5 2e-27 96.7 26.5 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 CCU99586.1 - 3.1e-12 46.5 0.0 2.8e-11 43.4 0.0 2.5 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.32 CCU99587.1 - 6.9e-09 36.2 0.1 0.019 15.8 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU99587.1 - 1.6e-08 34.7 0.0 0.0031 17.8 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCU99587.1 - 0.024 13.6 0.0 0.049 12.6 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CCU99587.1 - 0.053 13.5 0.0 1.8 8.6 0.0 3.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 CCU99587.1 - 0.079 13.5 3.9 20 5.9 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain MMS1_N PF10433.9 CCU99587.1 - 0.13 10.8 0.0 2.7 6.5 0.0 2.5 2 1 2 4 4 4 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ PF01011.21 CCU99587.1 - 0.16 12.0 0.1 83 3.4 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat XPA_C PF05181.12 CCU99589.1 - 1.9e-15 56.6 4.6 8.4e-14 51.3 4.6 2.8 1 1 0 1 1 1 1 XPA protein C-terminus DUF3689 PF12463.8 CCU99589.1 - 0.17 11.2 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) FYVE PF01363.21 CCU99589.1 - 0.29 11.3 3.2 5.9 7.1 0.2 2.5 2 0 0 2 2 2 0 FYVE zinc finger XPA_N PF01286.18 CCU99589.1 - 0.87 9.7 6.9 2.5 8.2 4.1 2.7 2 1 0 2 2 2 0 XPA protein N-terminal SRI PF08236.11 CCU99590.1 - 3.3e-19 68.8 1.2 7.2e-19 67.8 1.2 1.6 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 CCU99590.1 - 5.5e-19 69.2 3.6 5.6e-18 65.9 0.1 2.7 2 1 0 2 2 2 1 SET domain AWS PF17907.1 CCU99590.1 - 8.5e-15 54.5 6.3 8.5e-15 54.5 6.3 2.5 2 0 0 2 2 2 1 AWS domain Sod_Fe_C PF02777.18 CCU99592.1 - 1e-34 118.7 0.3 1.6e-34 118.1 0.3 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CCU99592.1 - 1.6e-31 108.6 0.8 1.6e-31 108.6 0.8 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RNA_pol PF00940.19 CCU99593.1 - 4.6e-176 585.7 0.0 6.2e-176 585.3 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CCU99593.1 - 1.8e-95 320.2 5.0 2.7e-95 319.6 5.0 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 CCU99593.1 - 0.00027 21.1 0.0 0.066 13.4 0.0 2.5 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 CCU99593.1 - 0.0061 16.7 0.2 5.3 7.5 0.0 3.6 3 0 0 3 3 3 1 PPR repeat DUF4440 PF14534.6 CCU99593.1 - 0.046 14.1 0.2 0.24 11.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Tropomyosin_1 PF12718.7 CCU99593.1 - 0.089 12.9 4.9 0.24 11.6 4.9 1.7 1 0 0 1 1 1 0 Tropomyosin like DUF1451 PF07295.11 CCU99593.1 - 5.3 7.1 11.4 52 3.9 0.1 3.7 4 0 0 4 4 4 0 Zinc-ribbon containing domain GMC_oxred_N PF00732.19 CCU99594.1 - 1.7e-38 132.7 0.4 2.3e-38 132.3 0.4 1.2 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CCU99594.1 - 1.2e-08 34.5 6.6 9.7e-06 24.9 1.4 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 CCU99594.1 - 1.4e-06 28.2 7.7 0.0049 16.5 4.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CCU99594.1 - 9.9e-05 21.7 1.2 0.00024 20.5 1.2 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CCU99594.1 - 0.00022 20.5 0.4 0.00035 19.9 0.4 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CCU99594.1 - 0.00034 20.8 2.0 0.0012 19.0 2.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CCU99594.1 - 0.00071 18.9 0.1 0.0014 17.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CCU99594.1 - 0.007 16.9 0.1 0.024 15.2 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CCU99594.1 - 0.058 12.4 0.1 0.086 11.9 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 CCU99594.1 - 0.12 11.9 2.3 0.22 11.1 2.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 CCU99594.1 - 0.23 10.1 3.5 0.15 10.7 1.4 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 CCU99594.1 - 0.4 10.0 5.7 0.74 9.1 3.7 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase PMT PF02366.18 CCU99595.1 - 4.8e-72 242.5 11.8 1e-71 241.4 11.8 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCU99595.1 - 3.6e-58 196.5 1.5 3.6e-58 196.5 1.5 2.3 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCU99595.1 - 1.3e-13 51.2 0.8 4.4e-13 49.5 0.8 1.8 1 1 0 1 1 1 1 MIR domain Transposase_20 PF02371.16 CCU99595.1 - 0.064 13.6 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family Aldose_epim PF01263.20 CCU99596.1 - 2.3e-25 89.5 0.0 9.5e-25 87.5 0.0 1.9 1 1 0 1 1 1 1 Aldose 1-epimerase Kelch_3 PF13415.6 CCU99597.1 - 8.3e-16 57.8 3.0 0.0019 18.5 0.0 5.0 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.6 CCU99597.1 - 5.1e-11 42.4 5.8 0.0011 19.0 0.0 5.8 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CCU99597.1 - 7e-11 41.9 0.9 3.8e-05 23.6 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CCU99597.1 - 0.00075 19.4 0.1 0.053 13.5 0.0 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 CCU99597.1 - 0.18 11.4 1.2 19 4.9 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.6 CCU99597.1 - 0.34 11.3 3.1 5.8 7.3 0.2 3.5 3 1 1 4 4 4 0 Kelch motif DUF3074 PF11274.8 CCU99598.1 - 1.8e-41 142.2 0.0 2.5e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Adaptin_N PF01602.20 CCU99599.1 - 1.5e-136 456.0 3.7 1.8e-136 455.8 3.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCU99599.1 - 1.8e-58 197.1 4.1 2.5e-56 190.2 0.1 3.0 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCU99599.1 - 1.8e-17 63.5 7.0 9.6e-05 22.7 0.1 6.0 2 1 4 6 6 6 5 HEAT repeats HEAT PF02985.22 CCU99599.1 - 1.8e-12 46.4 0.7 0.031 14.5 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat Cnd3 PF12719.7 CCU99599.1 - 4.3e-07 29.4 0.2 8.7e-05 21.9 0.2 2.7 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 CCU99599.1 - 3.6e-06 27.3 2.2 0.69 10.5 0.1 6.4 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 CCU99599.1 - 0.00063 19.4 0.2 0.92 9.0 0.0 3.1 2 2 1 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 CCU99599.1 - 0.0083 16.3 2.0 2.1 8.6 0.0 4.5 3 2 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 CCU99599.1 - 0.0099 15.8 0.4 0.072 13.0 0.1 2.6 1 1 1 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Cohesin_HEAT PF12765.7 CCU99599.1 - 0.17 12.2 2.2 43 4.5 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion RrnaAD PF00398.20 CCU99600.1 - 6.9e-60 202.4 0.0 1.2e-59 201.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CCU99600.1 - 8.1e-08 32.9 0.0 1.8e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCU99600.1 - 1.8e-06 28.5 0.0 3.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCU99600.1 - 1.1e-05 26.0 0.0 2.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCU99600.1 - 4.1e-05 23.2 0.0 6.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CCU99600.1 - 0.00074 19.3 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 CCU99600.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 CCU99600.1 - 0.0018 17.9 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 CCU99600.1 - 0.0045 16.3 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 CCU99600.1 - 0.0054 16.1 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_28 PF02636.17 CCU99600.1 - 0.022 14.4 0.1 0.043 13.4 0.1 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 CCU99600.1 - 0.036 13.9 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CCU99600.1 - 0.045 13.1 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family APC1_C PF18122.1 CCU99601.1 - 9.3e-13 48.5 0.0 1.7e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 CCU99601.1 - 7.4e-08 32.5 17.9 0.00049 20.4 0.0 6.4 6 0 0 6 6 6 4 Proteasome/cyclosome repeat ANAPC1 PF12859.7 CCU99601.1 - 2.6e-07 31.3 0.0 6e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 SPA PF08616.10 CCU99602.1 - 8e-24 83.8 0.0 1.3e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 CCU99602.1 - 1.9e-06 28.4 0.0 3.1e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 CCU99602.1 - 0.19 10.4 0.0 20 3.8 0.0 2.6 3 0 0 3 3 3 0 Transport protein Avl9 DUF2347 PF09804.9 CCU99602.1 - 0.2 11.2 0.0 15 5.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) GCFC PF07842.12 CCU99604.1 - 1.2e-61 208.7 10.7 2e-61 208.1 10.7 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 CCU99604.1 - 2.2e-10 40.2 3.2 2.4e-10 40.1 1.2 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CCU99604.1 - 0.00013 21.9 0.1 0.0053 16.8 0.1 2.8 2 0 0 2 2 2 1 G-patch domain Cyclin_N PF00134.23 CCU99605.1 - 1.6e-10 40.8 0.0 3.4e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 CCU99605.1 - 0.064 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat TPP_enzyme_N PF02776.18 CCU99606.1 - 4.3e-51 172.9 0.3 1.7e-50 171.0 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CCU99606.1 - 6.3e-48 162.4 0.0 2.1e-46 157.5 0.0 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCU99606.1 - 2.1e-38 131.2 0.2 5.1e-38 129.9 0.2 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 CCU99606.1 - 0.031 14.1 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Ank_2 PF12796.7 CCU99608.1 - 1.4e-09 38.4 0.2 2.4e-09 37.6 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CCU99608.1 - 1.8e-08 34.4 0.6 0.013 15.9 0.0 3.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 CCU99608.1 - 8.6e-08 32.6 1.0 0.0014 19.1 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCU99608.1 - 7.7e-07 29.0 0.1 0.16 12.7 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CCU99608.1 - 9.3e-07 29.0 3.0 0.00047 20.4 0.2 3.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Nrap_D4 PF17405.2 CCU99609.1 - 2.4e-53 180.7 0.0 5.1e-53 179.6 0.0 1.6 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 CCU99609.1 - 9.7e-46 155.3 0.0 2.1e-44 151.0 0.0 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D5 PF17406.2 CCU99609.1 - 9.3e-43 145.8 1.0 2.1e-42 144.7 0.5 1.9 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 CCU99609.1 - 1.8e-38 132.0 0.0 2.7e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 CCU99609.1 - 1e-31 110.0 0.0 2.5e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap_D3 PF17404.2 CCU99609.1 - 1.9e-31 109.3 0.0 4.6e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 PI31_Prot_C PF08577.11 CCU99610.1 - 8.1e-10 39.7 11.9 1.7e-09 38.7 11.9 1.6 1 0 0 1 1 1 1 PI31 proteasome regulator PI31_Prot_N PF11566.8 CCU99610.1 - 4.7e-05 23.3 0.2 0.0014 18.4 0.2 2.1 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal GPP34 PF05719.11 CCU99611.1 - 6.7e-60 202.6 0.4 8.9e-60 202.2 0.4 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) VASt PF16016.5 CCU99612.1 - 6.7e-38 130.5 0.4 6.7e-38 130.5 0.4 1.9 3 0 0 3 3 3 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CCU99612.1 - 1.9e-23 82.5 0.0 5.8e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 GRAM domain Cluap1 PF10234.9 CCU99612.1 - 0.054 12.9 0.5 0.1 12.0 0.5 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 DEAD PF00270.29 CCU99613.1 - 1.4e-40 138.9 0.0 2.1e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU99613.1 - 1.9e-20 73.3 0.0 7.2e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCU99613.1 - 6.3e-18 64.8 0.0 1.3e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCU99613.1 - 2.3e-06 27.7 0.0 6.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit VAD1-2 PF15310.6 CCU99613.1 - 0.1 12.5 1.5 0.16 11.8 1.5 1.2 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling SBF_like PF13593.6 CCU99613.1 - 0.14 11.4 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) Sporozoite_P67 PF05642.11 CCU99613.1 - 0.2 9.7 1.0 0.3 9.1 1.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3682 PF12446.8 CCU99613.1 - 1.7 9.1 6.4 4.7 7.7 6.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Pribosyltran_N PF13793.6 CCU99614.1 - 2.3e-36 124.3 0.2 2e-34 118.0 0.1 2.6 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CCU99614.1 - 3.7e-34 118.4 0.6 4e-33 115.0 0.6 2.1 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CCU99614.1 - 6.7e-16 58.2 0.1 3.3e-15 55.9 0.0 2.2 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCU99614.1 - 0.0057 16.1 0.0 0.0096 15.4 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PWI PF01480.17 CCU99615.1 - 8e-28 96.6 0.0 1.4e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 PWI domain WD40 PF00400.32 CCU99616.1 - 2.5e-57 189.5 13.5 2.6e-09 37.5 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 CCU99616.1 - 1.3e-23 83.1 5.2 2.1e-23 82.4 5.2 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 CCU99616.1 - 4.7e-23 81.3 0.0 1.7e-06 28.2 0.0 6.1 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCU99616.1 - 2e-08 33.6 0.1 0.85 8.5 0.0 5.0 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CCU99616.1 - 1.3e-07 31.3 0.0 0.22 10.8 0.0 4.2 5 0 0 5 5 5 2 WD40-like domain PD40 PF07676.12 CCU99616.1 - 6.6e-05 22.7 0.3 9.6 6.3 0.0 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 CCU99616.1 - 0.013 14.8 0.1 2.5 7.3 0.0 3.3 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 CCU99616.1 - 0.044 12.3 0.0 0.4 9.1 0.0 1.9 1 1 0 1 1 1 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 CCU99616.1 - 0.081 12.6 0.1 5.4 6.8 0.0 2.9 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature CEP63 PF17045.5 CCU99616.1 - 0.082 12.8 1.5 0.12 12.2 1.5 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa DUF5122 PF17164.4 CCU99616.1 - 0.17 12.2 0.3 1.2e+02 3.1 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller HOOK PF05622.12 CCU99616.1 - 0.19 9.8 0.6 0.26 9.4 0.6 1.1 1 0 0 1 1 1 0 HOOK protein PKcGMP_CC PF16808.5 CCU99616.1 - 0.2 11.6 3.1 0.7 9.8 0.8 2.4 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase INCENP_ARK-bind PF03941.15 CCU99617.1 - 1.3e-11 44.3 0.3 3.2e-11 43.0 0.3 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DUF4807 PF16065.5 CCU99619.1 - 0.068 12.8 0.6 0.12 12.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) PBP_sp32 PF07222.12 CCU99619.1 - 0.14 11.5 4.0 0.26 10.7 4.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PhoLip_ATPase_C PF16212.5 CCU99620.1 - 2.7e-71 240.3 24.6 2.7e-71 240.3 24.6 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCU99620.1 - 2.6e-18 65.5 2.7 7.2e-18 64.0 2.7 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CCU99620.1 - 8.3e-14 51.4 0.6 3.1e-13 49.6 0.0 2.2 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCU99620.1 - 7.6e-10 39.4 1.7 8.2e-05 23.0 0.3 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CCU99620.1 - 0.00011 21.7 0.3 0.003 17.1 0.3 2.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CCU99620.1 - 0.00072 19.4 1.2 0.0085 15.9 0.1 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF309 PF03745.14 CCU99621.1 - 1.7 8.3 5.1 7.1 6.4 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF309) Acyl-CoA_dh_1 PF00441.24 CCU99622.1 - 1.4e-44 152.0 3.8 1.4e-44 152.0 3.8 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CCU99622.1 - 6.2e-27 94.5 0.5 1.3e-26 93.5 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CCU99622.1 - 1.3e-23 83.0 0.0 2.2e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CCU99622.1 - 9e-21 74.5 0.9 1.5e-20 73.8 0.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Prefoldin_2 PF01920.20 CCU99622.1 - 0.094 12.7 1.5 3.1 7.8 0.1 2.6 3 0 0 3 3 3 0 Prefoldin subunit HpaB_N PF11794.8 CCU99622.1 - 0.1 12.3 0.2 0.39 10.3 0.2 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 CCU99622.1 - 0.16 12.0 0.4 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Staphylococcal AgrD protein Tfb2 PF03849.14 CCU99623.1 - 2.2e-86 290.0 2.2 6e-75 252.4 0.1 2.2 1 1 1 2 2 2 2 Transcription factor Tfb2 Rad54_N PF08658.10 CCU99623.1 - 1.1e-42 146.3 0.7 2.1e-42 145.3 0.7 1.4 1 0 0 1 1 1 1 Rad54 N terminal SNF2_N PF00176.23 CCU99623.1 - 1.2e-31 109.8 0.2 8.1e-22 77.4 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Tfb2_C PF18307.1 CCU99623.1 - 1.4e-16 60.6 0.1 4.1e-16 59.2 0.1 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CCU99623.1 - 0.014 15.5 0.1 0.055 13.6 0.0 1.9 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Mei5 PF10376.9 CCU99623.1 - 0.16 11.8 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein Methyltransf_15 PF09445.10 CCU99625.1 - 3.7e-23 81.9 1.5 2.1e-17 63.2 0.0 2.8 1 1 1 2 2 2 2 RNA cap guanine-N2 methyltransferase Aminotran_1_2 PF00155.21 CCU99626.1 - 2.2e-40 139.0 0.0 2.6e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CCU99626.1 - 0.0053 15.3 0.0 0.0086 14.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme WD40 PF00400.32 CCU99627.1 - 9.7e-36 121.2 21.1 1.5e-09 38.3 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CCU99627.1 - 9e-27 93.9 0.0 1.8e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CCU99627.1 - 1.2e-09 38.3 0.0 0.00079 19.7 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCU99627.1 - 0.00027 20.0 0.1 0.099 11.6 0.0 3.7 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CCU99627.1 - 0.00033 19.4 0.6 0.3 9.7 0.1 3.8 4 0 0 4 4 4 1 Nucleoporin Nup120/160 LisH PF08513.11 CCU99627.1 - 0.087 12.8 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 LisH Aldo_ket_red PF00248.21 CCU99628.1 - 2.5e-51 174.6 0.0 2.5e-49 168.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TPR_8 PF13181.6 CCU99629.1 - 1.5e-05 24.8 0.1 0.032 14.4 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCU99629.1 - 2.4e-05 24.1 6.1 0.00034 20.5 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCU99629.1 - 0.00021 20.9 0.0 0.22 11.4 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCU99629.1 - 0.00051 20.2 0.7 0.46 11.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCU99629.1 - 0.013 16.1 0.0 0.013 16.1 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Paf67 PF10255.9 CCU99629.1 - 0.11 11.5 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TPR_7 PF13176.6 CCU99629.1 - 0.16 12.0 5.5 18 5.6 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCU99629.1 - 0.66 10.5 4.1 34 5.0 0.1 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CCU99629.1 - 2.4 9.2 27.5 3 8.9 0.1 8.4 7 1 1 8 8 8 0 Tetratricopeptide repeat LRR_6 PF13516.6 CCU99630.1 - 3.6e-21 73.4 5.1 0.056 13.5 0.0 10.5 11 0 0 11 11 11 6 Leucine Rich repeat F-box-like PF12937.7 CCU99630.1 - 2.1e-12 46.7 2.7 2.1e-12 46.7 2.7 2.7 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 CCU99630.1 - 2e-11 43.9 0.0 1.3 9.5 0.0 7.2 3 2 4 8 8 8 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CCU99630.1 - 5e-05 23.3 3.1 82 4.4 0.0 8.1 8 1 0 8 8 8 0 Leucine Rich Repeat F-box PF00646.33 CCU99630.1 - 0.0049 16.7 3.1 0.0063 16.4 0.2 2.8 3 0 0 3 3 3 1 F-box domain SAM_Ste50p PF09235.10 CCU99630.1 - 0.0062 16.7 7.1 17 5.8 0.0 5.2 3 1 2 5 5 5 1 Ste50p, sterile alpha motif Coatomer_WDAD PF04053.14 CCU99631.1 - 1.3e-134 449.6 0.0 4e-134 448.0 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 CCU99631.1 - 7.5e-39 131.0 10.2 3.2e-07 30.9 0.3 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU99631.1 - 7.2e-09 35.8 0.3 0.015 15.6 0.0 5.2 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCU99631.1 - 0.029 13.0 2.9 0.23 10.0 0.3 3.2 1 1 3 4 4 4 0 Nucleoporin Nup120/160 Myb_DNA-binding PF00249.31 CCU99632.1 - 4e-13 49.3 0.9 8.9e-13 48.2 0.9 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCU99632.1 - 8.9e-08 32.3 0.7 1.7e-07 31.4 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF202 PF02656.15 CCU99633.1 - 1.2e-13 51.3 6.9 1.2e-13 51.3 6.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Pro_isomerase PF00160.21 CCU99634.1 - 4.5e-32 111.5 0.0 1e-31 110.3 0.0 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RTP1_C1 PF10363.9 CCU99635.1 - 5e-31 107.2 1.5 7.2e-31 106.7 0.1 2.1 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 CCU99635.1 - 3.6e-07 29.7 2.8 2.2e-06 27.2 1.2 3.3 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 2 Urb2 PF10441.9 CCU99635.1 - 0.015 15.2 1.3 0.24 11.3 0.3 2.5 2 0 0 2 2 2 0 Urb2/Npa2 family Palm_thioest PF02089.15 CCU99637.1 - 4.5e-76 255.9 0.0 5.4e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 CCU99637.1 - 0.028 14.0 0.0 0.083 12.5 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Tmem26 PF09772.9 CCU99637.1 - 0.18 11.2 0.0 0.79 9.0 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 26 MBOAT PF03062.19 CCU99638.1 - 5.1e-46 157.6 12.0 8.6e-46 156.9 12.0 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Erv26 PF04148.13 CCU99638.1 - 0.0094 15.8 0.1 0.026 14.3 0.0 1.7 2 0 0 2 2 2 1 Transmembrane adaptor Erv26 ThrE_2 PF12821.7 CCU99638.1 - 0.2 11.8 5.6 0.21 11.7 1.2 2.7 2 0 0 2 2 2 0 Threonine/Serine exporter, ThrE WD40 PF00400.32 CCU99639.1 - 1.2e-32 111.4 12.5 0.00015 22.5 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Vps5 PF09325.10 CCU99639.1 - 1.1e-15 57.8 5.6 2e-15 57.0 5.6 1.3 1 0 0 1 1 1 1 Vps5 C terminal like ANAPC4_WD40 PF12894.7 CCU99639.1 - 1.6e-08 34.7 0.0 0.13 12.6 0.0 4.7 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCU99639.1 - 0.00089 18.3 0.1 0.19 10.7 0.0 3.3 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 CCU99639.1 - 0.18 10.7 0.0 0.34 9.8 0.0 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 CCU99639.1 - 0.67 10.0 2.9 36 4.5 0.1 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat HrpB2 PF09487.10 CCU99639.1 - 2.3 8.7 5.9 3.3 8.2 0.2 3.0 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) GTP_EFTU PF00009.27 CCU99640.1 - 2.1e-53 180.8 0.0 3.1e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CCU99640.1 - 2e-07 31.0 0.0 4.5e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CCU99640.1 - 9e-06 26.0 0.0 2.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 CCU99640.1 - 1.5e-05 24.7 0.0 3.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 CCU99640.1 - 0.002 18.2 0.0 0.0055 16.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 CCU99640.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Ras family ADH_zinc_N_2 PF13602.6 CCU99641.1 - 1.4e-10 42.3 0.0 4.2e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCU99641.1 - 0.0002 21.2 0.1 0.00037 20.3 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCU99641.1 - 0.00023 21.1 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LRR_4 PF12799.7 CCU99642.1 - 2.1e-08 34.3 0.0 0.00027 21.2 0.0 3.5 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCU99642.1 - 4.5e-08 32.7 1.6 0.0005 19.8 0.7 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 CCU99642.1 - 1.5e-05 24.6 0.0 0.49 9.9 0.0 3.1 1 1 2 3 3 3 3 Leucine-rich repeat CAP_GLY PF01302.25 CCU99642.1 - 0.00011 22.1 0.1 0.00022 21.2 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_6 PF13516.6 CCU99642.1 - 0.039 14.0 4.0 8.4 6.7 0.0 4.1 5 0 0 5 5 5 0 Leucine Rich repeat RRM_1 PF00076.22 CCU99643.1 - 2.3e-09 36.9 0.0 0.00047 19.9 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioesterase PF00975.20 CCU99643.1 - 0.0069 16.5 0.1 0.091 12.9 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 CCU99643.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.15 CCU99643.1 - 0.19 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ribosomal_L7Ae PF01248.26 CCU99644.1 - 4.8e-28 96.7 1.3 5.8e-28 96.5 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_S17 PF00366.20 CCU99645.1 - 1.2e-25 89.4 0.7 2.1e-25 88.6 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 CCU99645.1 - 7.9e-22 77.4 0.0 1.9e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal DUF922 PF06037.11 CCU99645.1 - 0.033 14.0 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) Ribosomal_L1 PF00687.21 CCU99646.1 - 6.6e-47 159.9 3.1 7.5e-47 159.7 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DNA_pol_lambd_f PF10391.9 CCU99646.1 - 0.05 13.4 0.1 7.9 6.4 0.0 2.7 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda TCTP PF00838.17 CCU99649.1 - 4.9e-73 244.9 2.0 5.5e-73 244.8 2.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein IKBKB_SDD PF18397.1 CCU99649.1 - 0.048 13.0 0.1 0.057 12.7 0.1 1.1 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain RRM_1 PF00076.22 CCU99650.1 - 9.4e-18 63.8 0.0 1.4e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCU99650.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif CTNNBL PF08216.11 CCU99651.1 - 3.5e-28 97.8 0.0 7.4e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear E3_UbLigase_R4 PF13764.6 CCU99651.1 - 0.014 13.6 0.1 0.023 12.9 0.1 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 DUF1840 PF08895.11 CCU99651.1 - 3.3 8.1 7.7 3.2 8.1 0.3 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF1840) Vac14_Fab1_bd PF12755.7 CCU99652.1 - 1.8e-43 147.0 0.2 3e-38 130.3 0.0 4.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.8 CCU99652.1 - 4.4e-23 81.9 2.6 6.1e-23 81.4 1.3 1.9 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.22 CCU99652.1 - 6.4e-13 47.8 5.2 0.012 15.8 0.0 7.6 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 CCU99652.1 - 1.2e-07 32.0 6.5 0.34 11.3 0.0 5.9 5 1 1 6 6 6 2 HEAT repeats Cnd1 PF12717.7 CCU99652.1 - 1.9e-07 31.3 3.0 0.01 15.9 0.9 4.3 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CCU99652.1 - 2.7e-05 23.9 1.2 1.1 8.8 0.0 4.7 4 1 1 5 5 5 2 CLASP N terminal PXA PF02194.15 CCU99652.1 - 0.0063 16.5 0.7 1.9 8.4 0.7 2.8 1 1 0 1 1 1 1 PXA domain ParcG PF10274.9 CCU99652.1 - 0.0073 16.4 0.1 0.33 11.1 0.0 2.9 3 0 0 3 3 3 1 Parkin co-regulated protein Dopey_N PF04118.14 CCU99652.1 - 0.0078 15.4 0.5 0.059 12.5 0.3 2.4 2 1 0 2 2 2 1 Dopey, N-terminal MMS19_C PF12460.8 CCU99652.1 - 0.013 14.6 4.6 0.12 11.4 0.1 3.0 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 CCU99652.1 - 0.031 14.8 3.2 29 5.3 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat RTP1_C1 PF10363.9 CCU99652.1 - 0.084 13.1 1.2 8.3 6.6 0.2 3.4 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF5071 PF16804.5 CCU99652.1 - 0.17 12.1 1.2 3.8 7.8 0.0 3.5 4 1 0 4 4 4 0 Domain of unknown function (DUF5071) RasGEF_N_2 PF14663.6 CCU99652.1 - 1.3 9.4 4.7 10 6.5 0.1 3.9 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain UCH PF00443.29 CCU99653.1 - 1.6e-49 168.8 0.0 1.9e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCU99653.1 - 2.1e-16 60.4 0.0 3.8e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CCU99653.1 - 2e-05 24.2 0.1 0.5 9.8 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase CHASE2 PF05226.11 CCU99653.1 - 0.074 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 CHASE2 domain DZR PF12773.7 CCU99653.1 - 1.3 9.1 3.8 7.2 6.7 3.9 2.0 1 1 1 2 2 2 0 Double zinc ribbon Peptidase_C14 PF00656.22 CCU99654.1 - 1.2e-57 195.8 0.0 1.4e-57 195.5 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Antimicrobial23 PF16048.5 CCU99654.1 - 0.26 11.0 0.5 0.45 10.2 0.5 1.4 1 0 0 1 1 1 0 Frog antimicrobial peptide PH PF00169.29 CCU99655.1 - 1e-12 48.5 0.0 2.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 CCU99655.1 - 2.3e-12 46.6 0.2 4.9e-12 45.5 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CCU99655.1 - 5.9e-12 45.0 0.1 1.3e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 CCU99655.1 - 5.2e-08 32.9 0.0 7.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 CCU99655.1 - 2.5e-06 27.1 0.0 4.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 CCU99655.1 - 0.00045 20.6 0.1 0.00067 20.0 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 CCU99655.1 - 0.00077 19.2 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 CCU99655.1 - 0.0037 17.2 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain DnaJ PF00226.31 CCU99656.1 - 4e-19 68.5 0.8 4e-19 68.5 0.8 2.5 3 0 0 3 3 3 1 DnaJ domain MAGI_u5 PF16666.5 CCU99656.1 - 0.021 15.0 4.6 0.047 13.8 4.6 1.6 1 1 0 1 1 1 0 Unstructured region on MAGI NOB1_Zn_bind PF08772.11 CCU99657.1 - 2.3e-28 98.1 0.1 4.2e-28 97.3 0.1 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 CCU99657.1 - 1.6e-27 95.8 0.1 2.8e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease Ribosomal_60s PF00428.19 CCU99657.1 - 0.076 13.6 4.5 0.26 11.9 1.8 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-NADH-PPase PF09297.11 CCU99657.1 - 2.9 7.6 5.8 3.7 7.3 0.3 3.1 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 CCU99657.1 - 4.7 7.1 6.7 9.2 6.1 6.7 1.4 1 0 0 1 1 1 0 zinc-ribbon domain MWFE PF15879.5 CCU99658.1 - 2.3e-23 82.1 0.1 3e-23 81.7 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Cofilin_ADF PF00241.20 CCU99659.1 - 4.6e-10 39.3 0.0 5.5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ox_reductase_C PF08635.10 CCU99660.1 - 6.5e-71 236.5 0.0 9e-71 236.1 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 CCU99660.1 - 5.5e-24 85.3 0.0 1.3e-23 84.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Clathrin_lg_ch PF01086.17 CCU99662.1 - 1.9e-31 109.9 21.3 3.7e-28 99.2 21.3 2.4 1 1 0 1 1 1 1 Clathrin light chain V-ATPase_G PF03179.15 CCU99662.1 - 0.48 11.0 14.1 0.82 10.2 14.1 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Ribosomal_L13 PF00572.18 CCU99663.1 - 3.7e-54 182.3 0.0 4.4e-54 182.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 SMC_N PF02463.19 CCU99664.1 - 1.4e-13 50.8 0.0 2.7e-13 49.9 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCU99664.1 - 3e-11 44.2 20.1 1.9e-08 35.1 1.1 5.2 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CCU99664.1 - 0.0002 21.3 0.7 0.12 12.1 0.1 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ADIP PF11559.8 CCU99664.1 - 0.00089 19.4 10.9 0.00089 19.4 10.9 6.7 4 2 2 7 7 7 2 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 CCU99664.1 - 0.013 14.4 58.9 0.65 8.8 3.7 5.2 3 1 2 5 5 5 0 Spc7 kinetochore protein DivIC PF04977.15 CCU99664.1 - 0.015 15.0 0.1 0.015 15.0 0.1 8.5 6 4 3 9 9 9 0 Septum formation initiator AAA_29 PF13555.6 CCU99664.1 - 0.037 13.8 0.1 0.078 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FlgM PF04316.13 CCU99664.1 - 0.091 13.1 15.8 0.22 11.9 0.3 4.3 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM ABC_tran PF00005.27 CCU99664.1 - 0.18 12.3 0.0 0.18 12.3 0.0 4.5 4 1 0 4 4 4 0 ABC transporter LMBR1 PF04791.16 CCU99664.1 - 0.46 9.3 20.4 0.68 8.8 3.5 3.3 3 0 0 3 3 3 0 LMBR1-like membrane protein MTBP_N PF14918.6 CCU99664.1 - 0.58 9.6 11.3 0.02 14.4 2.2 2.7 2 1 1 3 3 3 0 MDM2-binding AAA PF00004.29 CCU99664.1 - 2.2 8.7 4.0 1.5 9.2 0.1 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) FlaC_arch PF05377.11 CCU99664.1 - 5.9 7.4 16.3 61 4.1 0.1 6.5 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) Cornichon PF03311.14 CCU99665.1 - 2.6e-47 160.1 13.4 3.2e-47 159.9 13.4 1.1 1 0 0 1 1 1 1 Cornichon protein MpPF26 PF07666.11 CCU99665.1 - 0.079 13.1 7.7 2.2 8.4 3.5 2.3 2 1 0 2 2 2 0 M penetrans paralogue family 26 CBFD_NFYB_HMF PF00808.23 CCU99666.1 - 8.1e-25 86.9 0.0 1.4e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CCU99666.1 - 0.0022 18.4 0.5 0.0041 17.5 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 ABC_tran PF00005.27 CCU99667.1 - 1e-45 155.6 0.1 7.5e-22 78.3 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CCU99667.1 - 4.9e-21 74.6 1.8 4.9e-21 74.6 1.8 2.6 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 CCU99667.1 - 4.6e-17 62.8 2.7 0.0026 17.6 0.2 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CCU99667.1 - 1.4e-10 42.0 3.4 0.0019 18.8 0.0 3.7 4 0 0 4 4 3 2 AAA domain SMC_N PF02463.19 CCU99667.1 - 5.4e-09 35.8 1.4 0.55 9.6 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCU99667.1 - 3.3e-08 33.2 0.2 0.0041 16.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CCU99667.1 - 1.9e-07 31.1 5.4 0.029 14.1 0.0 4.4 3 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 CCU99667.1 - 2e-07 31.0 1.1 0.00018 21.5 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 CCU99667.1 - 1.3e-06 28.5 0.3 0.003 17.6 0.1 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CCU99667.1 - 2.3e-06 28.1 0.0 0.099 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CCU99667.1 - 1.5e-05 25.3 0.8 0.49 10.7 0.1 3.5 2 2 1 3 3 3 2 AAA domain Dynamin_N PF00350.23 CCU99667.1 - 2.2e-05 24.6 4.4 0.12 12.4 0.0 4.0 2 1 1 3 3 3 2 Dynamin family AAA_28 PF13521.6 CCU99667.1 - 2.3e-05 24.7 0.0 0.21 11.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 CCU99667.1 - 5e-05 23.3 0.2 0.34 10.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 CCU99667.1 - 5.9e-05 22.9 0.2 1 9.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 CCU99667.1 - 0.00011 22.7 0.1 2 8.9 0.0 3.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 CCU99667.1 - 0.00068 19.2 0.1 0.045 13.3 0.1 2.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.6 CCU99667.1 - 0.00073 20.1 0.1 1.2 9.6 0.0 3.2 2 1 0 3 3 3 1 AAA domain DUF87 PF01935.17 CCU99667.1 - 0.0013 18.9 5.1 1.2 9.2 0.0 4.3 3 1 1 4 4 4 1 Helicase HerA, central domain AAA_33 PF13671.6 CCU99667.1 - 0.0013 18.9 0.2 0.98 9.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 CCU99667.1 - 0.0016 18.8 0.8 3.2 8.2 0.0 3.3 3 0 0 3 3 3 1 RNA helicase Roc PF08477.13 CCU99667.1 - 0.0029 17.8 0.1 3.6 7.8 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 CCU99667.1 - 0.0029 17.6 0.5 5.4 7.0 0.0 3.9 4 1 1 5 5 4 0 AAA domain NB-ARC PF00931.22 CCU99667.1 - 0.0038 16.4 0.0 0.48 9.6 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Pox_A32 PF04665.12 CCU99667.1 - 0.0046 16.5 1.1 0.66 9.4 0.0 3.0 3 1 0 3 3 3 1 Poxvirus A32 protein Zeta_toxin PF06414.12 CCU99667.1 - 0.011 15.0 0.1 0.84 8.9 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin AAA_5 PF07728.14 CCU99667.1 - 0.011 15.7 0.4 4.8 7.2 0.1 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 CCU99667.1 - 0.012 15.0 0.1 2.3 7.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 CCU99667.1 - 0.014 15.1 3.9 1.4 8.6 0.0 3.7 5 0 0 5 5 4 0 AAA domain cobW PF02492.19 CCU99667.1 - 0.016 14.8 0.2 3.6 7.1 0.0 2.9 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 CCU99667.1 - 0.019 14.6 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 CCU99667.1 - 0.019 14.5 0.1 2 7.9 0.1 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_25 PF13481.6 CCU99667.1 - 0.022 14.3 0.0 4.4 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 CCU99667.1 - 0.027 14.4 0.1 10 6.0 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase PF06745.13 CCU99667.1 - 0.043 13.1 0.1 5.6 6.2 0.0 3.2 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.26 CCU99667.1 - 0.06 13.0 0.0 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain MeaB PF03308.16 CCU99667.1 - 0.063 12.2 0.0 12 4.7 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 CCU99667.1 - 0.065 13.7 0.6 3.5 8.0 0.0 3.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CCU99667.1 - 0.074 13.1 0.4 5.3 7.1 0.1 3.0 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 CCU99667.1 - 0.075 12.8 0.7 13 5.6 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 CCU99667.1 - 0.092 12.5 0.1 9 6.0 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 CCU99667.1 - 0.18 11.7 5.4 2.8 7.8 0.1 3.7 4 0 0 4 4 3 0 NTPase Septin PF00735.18 CCU99667.1 - 0.29 10.4 6.1 4 6.6 0.0 3.0 4 0 0 4 4 3 0 Septin DivIC PF04977.15 CCU99667.1 - 1.3 8.8 7.4 5.9 6.7 1.5 2.7 2 0 0 2 2 2 0 Septum formation initiator SRP54 PF00448.22 CCU99667.1 - 3.4 7.2 7.0 4.4 6.9 0.0 3.2 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain MRP-L27 PF09809.9 CCU99668.1 - 0.00033 20.5 0.0 0.00066 19.5 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 LRR_8 PF13855.6 CCU99669.1 - 2.3e-06 27.3 1.0 3.4e-06 26.7 0.2 1.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 CCU99669.1 - 0.00081 19.3 2.4 5.7 7.3 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 CCU99669.1 - 0.0021 18.4 0.8 0.011 16.2 0.1 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CCU99669.1 - 0.11 13.2 1.5 33 5.6 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat UDPGP PF01704.18 CCU99670.1 - 1.3e-201 669.6 0.1 1.5e-201 669.4 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Mito_carr PF00153.27 CCU99671.1 - 5.3e-47 157.7 5.3 1.8e-16 59.9 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MDM31_MDM32 PF08118.11 CCU99672.1 - 4.6e-144 481.0 0.0 8.1e-104 348.2 0.0 2.3 2 1 0 2 2 2 2 Yeast mitochondrial distribution and morphology (MDM) proteins Aim19 PF10315.9 CCU99673.1 - 1.9e-16 60.4 0.5 2.3e-16 60.1 0.5 1.1 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF3918 PF13056.6 CCU99673.1 - 0.36 10.5 1.5 0.6 9.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Snf7 PF03357.21 CCU99674.1 - 4.6e-08 32.9 13.7 8.6e-08 32.0 13.7 1.5 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.14 CCU99674.1 - 0.003 17.5 2.9 0.0044 17.0 2.9 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway YojJ PF10372.9 CCU99674.1 - 0.099 12.7 0.2 12 6.1 0.0 2.6 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus DMSP_lyase PF16867.5 CCU99674.1 - 0.17 11.5 0.5 0.8 9.3 0.0 2.1 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase FAM117 PF15388.6 CCU99674.1 - 0.21 11.0 2.0 0.26 10.7 2.0 1.2 1 0 0 1 1 1 0 Protein Family FAM117 Halogen_Hydrol PF10112.9 CCU99675.1 - 0.21 11.6 5.1 8.2 6.4 0.1 2.8 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein CENP-H PF05837.12 CCU99675.1 - 9.6 6.7 33.8 7.8 6.9 0.6 4.6 3 1 1 4 4 4 0 Centromere protein H (CENP-H) Chitin_synth_2 PF03142.15 CCU99676.1 - 1.3e-236 786.3 0.0 2.2e-236 785.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CCU99676.1 - 3e-56 191.0 0.0 2.8e-53 181.2 0.0 2.2 2 0 0 2 2 2 2 Myosin head (motor domain) Cyt-b5 PF00173.28 CCU99676.1 - 3.3e-18 65.6 2.1 6.7e-11 42.2 0.2 3.0 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 CCU99676.1 - 2.3e-11 44.0 0.0 3.6e-09 36.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DEK_C PF08766.11 CCU99676.1 - 2.8e-11 43.2 0.0 9.4e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 CCU99676.1 - 9.5e-11 42.0 3.4 9.5e-11 42.0 3.4 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CCU99676.1 - 2.8e-07 30.5 0.0 0.0019 18.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CCU99676.1 - 0.0045 16.5 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 BPL_LplA_LipB PF03099.19 CCU99677.1 - 0.0001 22.2 0.0 0.00023 21.1 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Cnd3 PF12719.7 CCU99678.1 - 2.1e-75 253.7 8.7 4.1e-74 249.4 1.5 2.9 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CCU99678.1 - 8.1e-13 48.6 16.2 6.2e-09 36.1 1.2 5.5 6 0 0 6 6 5 3 HEAT repeats HEAT PF02985.22 CCU99678.1 - 8.2e-09 35.0 17.3 0.23 11.8 0.1 8.1 8 1 1 9 9 8 4 HEAT repeat Cnd1 PF12717.7 CCU99678.1 - 2.6e-06 27.5 8.0 0.00035 20.6 0.5 4.7 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CCU99678.1 - 2e-05 25.0 17.6 0.093 13.3 0.1 7.3 8 0 0 8 8 8 2 HEAT-like repeat IFRD PF05004.13 CCU99678.1 - 0.00073 18.7 7.5 0.0079 15.3 0.4 2.5 2 0 0 2 2 2 2 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 CCU99678.1 - 0.0079 14.8 0.3 0.31 9.6 0.3 3.0 3 1 0 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.8 CCU99678.1 - 0.012 15.2 0.1 0.44 10.1 0.1 2.8 3 0 0 3 3 3 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 CCU99678.1 - 0.055 14.1 0.6 15 6.3 0.3 3.8 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 CCU99678.1 - 0.11 12.7 2.1 2.7 8.2 0.2 3.7 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_N PF14500.6 CCU99678.1 - 0.16 11.5 4.6 1.3 8.6 0.7 3.4 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II V-ATPase_H_N PF03224.14 CCU99678.1 - 0.19 11.0 2.9 10 5.3 0.1 3.5 4 1 1 5 5 5 0 V-ATPase subunit H Sec7_N PF12783.7 CCU99678.1 - 0.37 10.7 5.2 0.27 11.1 0.6 3.2 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal BRO1 PF03097.18 CCU99679.1 - 6.2e-57 193.2 0.8 6.2e-57 193.2 0.8 1.4 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CCU99679.1 - 7.5e-41 140.3 1.4 1.5e-40 139.3 1.4 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV zf-RING_2 PF13639.6 CCU99680.1 - 2.8e-12 46.8 11.6 4.6e-12 46.1 11.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CCU99680.1 - 9.6e-10 38.6 8.8 1.8e-09 37.7 8.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CCU99680.1 - 3.4e-08 33.2 9.9 6.1e-08 32.4 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCU99680.1 - 2.8e-07 30.2 5.5 5.1e-07 29.3 5.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CCU99680.1 - 3.8e-07 29.9 9.7 6.5e-07 29.1 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCU99680.1 - 1.2e-06 28.4 8.3 1.9e-06 27.7 8.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CCU99680.1 - 1.6e-05 24.7 6.3 2.5e-05 24.1 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCU99680.1 - 1.9e-05 24.5 8.6 3.4e-05 23.6 8.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CCU99680.1 - 2.8e-05 24.1 2.7 5.4e-05 23.2 2.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CCU99680.1 - 0.00049 20.1 6.0 0.0011 19.0 6.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CCU99680.1 - 0.0051 16.4 9.2 0.0095 15.5 9.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 CCU99680.1 - 0.015 15.4 2.6 0.034 14.3 2.6 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 CCU99680.1 - 0.037 14.3 9.2 0.067 13.5 9.2 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 CCU99680.1 - 0.069 13.0 6.8 0.13 12.0 6.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 CCU99680.1 - 0.072 13.1 2.9 0.15 12.1 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 CCU99680.1 - 0.086 13.0 12.1 0.16 12.2 12.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-HC5HC2H PF13771.6 CCU99680.1 - 0.098 12.9 5.8 0.037 14.3 2.9 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain Zf_RING PF16744.5 CCU99680.1 - 0.29 11.3 5.8 0.64 10.2 5.8 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-Nse PF11789.8 CCU99680.1 - 0.46 10.3 3.8 0.96 9.3 3.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CCU99680.1 - 0.49 10.6 9.1 6.7 7.0 9.1 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING BAF1_ABF1 PF04684.13 CCU99680.1 - 1.7 7.6 9.3 12 4.8 9.2 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.13 CCU99680.1 - 4.6 7.1 11.6 5.9 6.8 11.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FANCL_C PF11793.8 CCU99680.1 - 9.6 6.5 10.1 28 5.0 10.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain SH3_2 PF07653.17 CCU99681.1 - 2.5e-06 27.1 0.0 5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CCU99681.1 - 4.4e-05 23.0 0.0 0.18 11.4 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CCU99681.1 - 0.042 13.7 0.1 0.12 12.3 0.1 1.8 1 1 0 1 1 1 0 Variant SH3 domain cobW PF02492.19 CCU99682.1 - 3.8e-50 169.9 1.3 2.3e-49 167.4 1.3 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain HIT PF01230.23 CCU99682.1 - 1.9e-28 99.0 0.2 5.1e-28 97.7 0.2 1.8 1 0 0 1 1 1 1 HIT domain CobW_C PF07683.14 CCU99682.1 - 6.3e-22 77.3 0.6 2.3e-15 56.3 0.0 3.1 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain DcpS_C PF11969.8 CCU99682.1 - 3.8e-08 33.8 0.1 9.3e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA_16 PF13191.6 CCU99682.1 - 0.0027 18.1 0.0 0.0058 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 CCU99682.1 - 0.0037 17.2 0.0 0.0081 16.2 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 CCU99682.1 - 0.017 14.1 0.1 5.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 CCU99682.1 - 0.023 13.7 0.0 0.063 12.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.14 CCU99682.1 - 0.026 14.4 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B JAKMIP_CC3 PF16034.5 CCU99682.1 - 0.044 13.7 0.1 0.078 12.9 0.1 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain Viral_helicase1 PF01443.18 CCU99682.1 - 0.09 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Peptidase_A25 PF03418.14 CCU99682.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Germination protease AAA_18 PF13238.6 CCU99682.1 - 0.34 11.5 1.5 5.9 7.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain PhetRS_B1 PF18262.1 CCU99682.1 - 0.41 10.9 1.7 1 9.6 0.0 2.4 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain BRF1 PF07741.13 CCU99683.1 - 1.2e-26 93.0 4.1 1.2e-26 93.0 4.1 2.8 3 0 0 3 3 3 2 Brf1-like TBP-binding domain Gag_p24 PF00607.20 CCU99683.1 - 0.23 11.3 3.0 0.28 11.0 0.8 1.9 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) TF_Zn_Ribbon PF08271.12 CCU99684.1 - 4.3e-10 39.0 0.2 6.2e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 CCU99684.1 - 0.016 14.6 2.2 0.19 11.2 2.5 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 CCU99684.1 - 0.086 12.6 1.0 6.7 6.6 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 CCU99684.1 - 0.11 12.2 1.4 7.1 6.5 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Vps36-NZF-N PF16988.5 CCU99684.1 - 0.17 11.3 0.1 0.17 11.3 0.1 2.0 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Nudix_N_2 PF14803.6 CCU99684.1 - 0.25 11.3 1.8 5.3 7.1 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal zn-ribbon_14 PF16503.5 CCU99684.1 - 1.2 8.7 6.1 3.6 7.2 6.1 1.7 1 1 0 1 1 1 0 Zinc-ribbon HisG PF01634.18 CCU99685.1 - 1.4e-52 177.9 0.0 1.8e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 CCU99685.1 - 2.1e-26 91.8 0.1 3.8e-26 91.0 0.1 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 CCU99685.1 - 0.004 17.1 0.1 0.01 15.8 0.1 1.6 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 CCU99685.1 - 0.043 13.2 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 AAA PF00004.29 CCU99686.1 - 6.6e-39 133.4 0.0 1.2e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCU99686.1 - 2.6e-10 40.0 0.0 5.2e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CCU99686.1 - 6.9e-07 29.2 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCU99686.1 - 1.3e-06 28.9 0.2 0.00015 22.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CCU99686.1 - 2.2e-05 24.7 0.0 4.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCU99686.1 - 2.3e-05 24.4 0.3 0.00017 21.6 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCU99686.1 - 5.5e-05 23.5 0.3 0.0017 18.6 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCU99686.1 - 0.00015 21.9 0.0 0.00028 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CCU99686.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCU99686.1 - 0.0003 21.3 0.0 0.00057 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CCU99686.1 - 0.00044 20.6 0.0 0.0023 18.3 0.0 2.2 1 1 1 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 CCU99686.1 - 0.00063 19.2 0.2 0.0016 17.9 0.2 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CCU99686.1 - 0.00076 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TniB PF05621.11 CCU99686.1 - 0.00097 18.6 0.0 1.6 8.1 0.0 2.4 1 1 1 2 2 2 2 Bacterial TniB protein Hydin_ADK PF17213.3 CCU99686.1 - 0.0012 19.2 0.3 1.1 9.5 0.1 3.0 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain TIP49 PF06068.13 CCU99686.1 - 0.0014 17.9 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 CCU99686.1 - 0.0018 18.0 0.2 0.0037 17.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CCU99686.1 - 0.0027 17.3 0.9 0.029 13.9 0.4 2.1 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CCU99686.1 - 0.0029 17.9 0.0 0.0051 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCU99686.1 - 0.0032 17.0 0.1 0.0081 15.7 0.1 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 CCU99686.1 - 0.0047 16.6 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CCU99686.1 - 0.0063 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 CCU99686.1 - 0.0065 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Guanylate_kin PF00625.21 CCU99686.1 - 0.0085 15.8 0.0 0.055 13.2 0.0 2.2 3 0 0 3 3 2 1 Guanylate kinase DUF815 PF05673.13 CCU99686.1 - 0.0099 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATPase PF06745.13 CCU99686.1 - 0.012 15.0 0.1 0.23 10.8 0.0 2.3 1 1 1 2 2 2 0 KaiC TsaE PF02367.17 CCU99686.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 CCU99686.1 - 0.016 15.2 0.1 0.1 12.5 0.0 2.2 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_21 PF13304.6 CCU99686.1 - 0.022 14.6 0.3 1.5 8.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Bac_DnaA PF00308.18 CCU99686.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein NACHT PF05729.12 CCU99686.1 - 0.023 14.6 0.2 0.053 13.4 0.1 1.7 2 0 0 2 2 1 0 NACHT domain AAA_17 PF13207.6 CCU99686.1 - 0.031 14.7 1.2 0.056 13.9 0.1 2.0 3 0 0 3 3 1 0 AAA domain AAA_6 PF12774.7 CCU99686.1 - 0.033 13.2 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_3 PF07726.11 CCU99686.1 - 0.04 13.8 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CCU99686.1 - 0.063 12.7 0.0 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein IPT PF01745.16 CCU99686.1 - 0.065 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase CPT PF07931.12 CCU99686.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 CCU99686.1 - 0.085 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 CCU99686.1 - 0.11 12.2 0.1 0.31 10.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CCU99686.1 - 0.12 12.9 0.2 0.4 11.2 0.1 1.8 2 1 0 2 2 1 0 ABC transporter Proteasome PF00227.26 CCU99687.1 - 6.6e-41 139.9 0.0 7.5e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Trans_coact PF16805.5 CCU99687.1 - 0.14 12.2 0.0 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Phage late-transcription coactivator Cation_efflux PF01545.21 CCU99688.1 - 7.5e-07 29.1 3.2 1.3e-06 28.3 3.2 1.4 1 0 0 1 1 1 1 Cation efflux family DUF3040 PF11239.8 CCU99688.1 - 1.4 9.3 5.0 0.9 9.9 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DNA_pol_delta_4 PF04081.13 CCU99689.1 - 3.1e-15 56.7 0.0 3.9e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 MT0933_antitox PF14013.6 CCU99689.1 - 0.14 12.5 1.2 0.29 11.5 1.2 1.4 1 0 0 1 1 1 0 MT0933-like antitoxin protein Met_10 PF02475.16 CCU99690.1 - 4.9e-62 209.2 0.0 6.5e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 CCU99690.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 CCU99690.1 - 0.12 13.1 0.3 0.57 10.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain zf-RING-like PF08746.11 CCU99690.1 - 0.22 11.9 4.5 3.4 8.0 0.3 2.5 2 0 0 2 2 2 0 RING-like domain Bromodomain PF00439.25 CCU99691.1 - 6.6e-10 38.9 0.2 1.5e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Bromodomain Acyltransferase PF01553.21 CCU99692.1 - 4.2e-18 65.3 0.0 5.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase zf-Tim10_DDP PF02953.15 CCU99693.1 - 1.1e-12 47.4 3.1 3e-07 30.0 0.3 2.2 1 1 1 2 2 2 2 Tim10/DDP family zinc finger PMEI PF04043.15 CCU99693.1 - 0.0045 17.3 1.4 0.0048 17.3 1.4 1.1 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor NPH3 PF03000.14 CCU99693.1 - 0.031 13.9 0.0 0.032 13.9 0.0 1.0 1 0 0 1 1 1 0 NPH3 family Pil1 PF13805.6 CCU99694.1 - 2.3e-14 53.6 1.0 2.3e-14 53.6 1.0 1.6 2 0 0 2 2 2 1 Eisosome component PIL1 MRG PF05712.13 CCU99695.1 - 2.5e-62 209.7 0.0 3.4e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 CCU99695.1 - 9.6e-10 38.2 0.2 2.3e-09 37.0 0.2 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 CCU99695.1 - 0.0064 16.4 1.1 0.02 14.8 1.1 1.9 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TetR_C_32 PF09209.11 CCU99695.1 - 0.032 14.2 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PWWP PF00855.17 CCU99695.1 - 0.054 13.9 0.2 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 PWWP domain BAR_2 PF10455.9 CCU99696.1 - 1.2e-35 123.1 0.6 3.1e-27 95.5 0.1 2.1 1 1 1 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CCU99696.1 - 5.8e-15 55.6 7.0 3.9e-14 52.9 7.0 1.9 1 1 0 1 1 1 1 BAR domain GAS PF13851.6 CCU99696.1 - 0.033 13.5 6.9 0.19 11.1 0.1 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 CCU99696.1 - 0.053 13.8 5.6 1.7 9.0 0.1 3.3 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 CCU99696.1 - 0.15 12.3 1.4 6.7 7.0 0.0 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.20 CCU99696.1 - 0.19 11.7 2.9 6.5 6.8 0.1 3.4 3 0 0 3 3 3 0 Prefoldin subunit BAR_3 PF16746.5 CCU99696.1 - 0.21 11.3 4.0 0.24 11.1 0.5 2.3 2 1 0 2 2 2 0 BAR domain of APPL family Seryl_tRNA_N PF02403.22 CCU99696.1 - 0.65 10.2 5.7 3 8.1 0.1 3.4 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Allexi_40kDa PF05549.11 CCU99696.1 - 0.82 9.1 3.9 0.62 9.5 0.2 2.2 2 1 0 2 2 2 0 Allexivirus 40kDa protein TPR_MLP1_2 PF07926.12 CCU99696.1 - 1.3 9.0 16.3 3.7 7.6 2.0 3.5 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Hrs_helical PF12210.8 CCU99696.1 - 1.9 9.0 9.2 19 5.9 0.3 3.7 2 1 2 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF16 PF01519.16 CCU99696.1 - 2 8.9 4.3 19 5.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF16 HSCB_C PF07743.13 CCU99696.1 - 3 8.4 9.7 1.8 9.1 0.7 3.9 2 2 2 5 5 5 0 HSCB C-terminal oligomerisation domain DUF1843 PF08898.10 CCU99696.1 - 5 7.7 7.5 1.3 9.6 0.1 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF1843) CPSase_L_D2 PF02786.17 CCU99697.1 - 9.6e-116 384.7 0.1 8.4e-84 280.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CCU99697.1 - 2.5e-49 166.4 0.0 2e-48 163.4 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 CCU99697.1 - 1.6e-44 151.5 0.3 4.3e-44 150.1 0.0 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 CCU99697.1 - 2.7e-43 148.0 0.0 7.9e-43 146.4 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 CCU99697.1 - 1.2e-42 145.1 0.1 2.4e-42 144.1 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 CCU99697.1 - 3.3e-30 105.2 0.0 6.9e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 CCU99697.1 - 1.9e-19 70.0 0.1 4e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CCU99697.1 - 4.3e-16 58.9 0.0 1.1e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 CCU99697.1 - 8.9e-12 45.1 0.0 5.4e-11 42.5 0.0 2.5 2 0 0 2 2 1 1 MGS-like domain ATPgrasp_Ter PF15632.6 CCU99697.1 - 2.2e-09 37.2 0.1 6.2e-05 22.7 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 CCU99697.1 - 3.3e-07 30.5 0.1 0.004 17.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 CCU99697.1 - 0.00016 21.5 0.6 0.029 14.1 0.6 2.8 1 1 0 1 1 1 1 Peptidase C26 CBFD_NFYB_HMF PF00808.23 CCU99698.1 - 7.3e-18 64.6 0.2 1.3e-17 63.8 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CCU99698.1 - 3.7e-05 24.1 0.2 3.7e-05 24.1 0.2 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 CCU99698.1 - 0.0015 18.6 0.2 0.0027 17.8 0.2 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CMS1 PF14617.6 CCU99699.1 - 3.7e-34 118.2 0.0 4.4e-33 114.7 0.0 2.2 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 CCU99699.1 - 0.017 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase RRM_1 PF00076.22 CCU99702.1 - 2.2e-06 27.4 0.0 6.5e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCU99702.1 - 0.092 12.6 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif Rad60-SLD PF11976.8 CCU99703.1 - 5.4e-24 83.8 0.3 6.3e-24 83.6 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CCU99703.1 - 4.1e-13 48.9 0.0 4.8e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TPR_1 PF00515.28 CCU99704.1 - 9.5e-45 148.7 4.5 1.4e-06 27.9 0.0 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 CCU99704.1 - 2.3e-40 133.4 6.4 1.7e-05 24.6 0.0 11.3 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_8 PF13181.6 CCU99704.1 - 5.7e-27 91.6 1.8 1.1e-05 25.3 0.0 9.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 CCU99704.1 - 3.1e-24 85.3 10.9 9.7e-07 29.3 0.0 7.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 CCU99704.1 - 1.8e-23 82.6 12.8 5.3e-05 23.4 0.6 7.7 3 3 5 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.6 CCU99704.1 - 3.8e-20 71.3 5.9 1.4e-07 31.1 0.0 8.0 6 1 2 8 8 8 4 TPR repeat TPR_17 PF13431.6 CCU99704.1 - 8.9e-18 63.3 5.2 0.0023 18.2 0.0 8.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CCU99704.1 - 4.4e-17 61.3 8.5 0.00027 21.5 0.0 9.3 4 2 7 11 11 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 CCU99704.1 - 8.1e-13 48.7 11.7 0.0025 18.3 0.2 6.3 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 CCU99704.1 - 2.2e-11 43.7 0.1 1.3e-05 25.2 0.0 5.8 3 2 3 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCU99704.1 - 1.4e-10 40.4 2.5 5.2 7.3 0.2 7.3 5 2 1 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCU99704.1 - 1.8e-10 40.9 4.7 0.0081 16.4 0.1 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CCU99704.1 - 3e-09 36.4 9.6 0.54 10.2 0.2 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CCU99704.1 - 6e-06 25.9 5.9 0.0038 16.6 0.2 4.0 3 1 1 4 4 4 2 MalT-like TPR region TPR_15 PF13429.6 CCU99704.1 - 9.5e-06 25.0 3.0 0.039 13.2 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCU99704.1 - 0.00022 21.7 4.4 14 6.6 0.0 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CCU99704.1 - 0.00026 21.0 4.7 0.33 11.1 0.0 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 5 MAS20 PF02064.15 CCU99704.1 - 0.0038 17.3 2.5 0.14 12.3 0.4 2.9 3 0 0 3 3 2 1 MAS20 protein import receptor TPR_4 PF07721.14 CCU99704.1 - 0.0043 17.6 0.3 0.49 11.2 0.0 4.3 5 0 0 5 5 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 CCU99704.1 - 0.0044 16.5 0.2 77 2.9 0.0 5.4 5 0 0 5 5 5 0 SHNi-TPR BTAD PF03704.17 CCU99704.1 - 0.012 16.0 0.3 1.4 9.4 0.0 3.6 2 2 2 4 4 4 0 Bacterial transcriptional activator domain NARP1 PF12569.8 CCU99704.1 - 0.018 14.0 11.6 0.1 11.5 0.0 4.1 2 2 2 5 5 5 0 NMDA receptor-regulated protein 1 MIT PF04212.18 CCU99704.1 - 0.054 13.6 3.3 2 8.5 0.1 4.2 5 0 0 5 5 3 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 CCU99704.1 - 0.15 12.4 4.7 13 6.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5102 PF17104.5 CCU99704.1 - 4.5 7.2 7.0 0.44 10.5 0.8 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5102) F-box-like PF12937.7 CCU99705.1 - 0.044 13.7 2.6 0.067 13.1 0.6 2.5 2 1 1 3 3 3 0 F-box-like F-box PF00646.33 CCU99705.1 - 0.07 13.0 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 F-box domain CRAL_TRIO PF00650.20 CCU99706.1 - 4.8e-26 91.4 0.0 7.3e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCU99706.1 - 1.9e-06 28.0 0.9 4e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain EOS1 PF12326.8 CCU99707.1 - 1.7e-47 161.6 1.1 2.5e-47 161.1 1.1 1.3 1 0 0 1 1 1 1 N-glycosylation protein TT_ORF1 PF02956.14 CCU99707.1 - 3.5 6.2 9.1 3.6 6.1 9.1 1.1 1 0 0 1 1 1 0 TT viral orf 1 Mago_nashi PF02792.14 CCU99708.1 - 1.1e-65 220.1 1.0 1.3e-65 219.8 1.0 1.0 1 0 0 1 1 1 1 Mago nashi protein Cpn10 PF00166.21 CCU99709.1 - 1.2e-27 95.8 0.0 1.4e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.24 CCU99710.1 - 1.4e-90 304.3 6.5 2.5e-90 303.5 6.5 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mito_carr PF00153.27 CCU99711.1 - 3.9e-71 235.1 0.4 8.9e-24 83.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3944 PF13099.6 CCU99711.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) Tail_VII PF17091.5 CCU99711.1 - 0.89 9.5 3.0 15 5.6 0.4 2.5 2 0 0 2 2 2 0 Inovirus G7P protein SMC_N PF02463.19 CCU99712.1 - 6e-68 228.6 0.0 1.4e-67 227.3 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCU99712.1 - 6.3e-19 68.4 1.9 4.3e-18 65.7 1.2 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CCU99712.1 - 2.4e-11 44.0 1.4 3e-05 24.0 0.2 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CCU99712.1 - 2.7e-11 44.3 22.8 2.7e-11 44.3 22.8 5.3 3 2 0 3 3 2 1 AAA domain AAA_15 PF13175.6 CCU99712.1 - 3.5e-07 30.3 0.3 1.3e-05 25.1 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CCU99712.1 - 3.7e-05 23.4 0.0 0.00011 21.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Golgin_A5 PF09787.9 CCU99712.1 - 5.9e-05 22.7 8.0 5.9e-05 22.7 8.0 6.3 3 2 4 7 7 6 1 Golgin subfamily A member 5 Spc7 PF08317.11 CCU99712.1 - 0.00017 20.6 91.1 0.026 13.4 5.2 6.4 2 2 3 6 6 6 4 Spc7 kinetochore protein ABC_tran PF00005.27 CCU99712.1 - 0.0083 16.6 15.7 0.49 10.9 0.0 5.2 4 1 0 4 4 4 2 ABC transporter HALZ PF02183.18 CCU99712.1 - 0.012 15.8 8.5 0.98 9.7 0.1 5.6 4 1 1 5 5 5 0 Homeobox associated leucine zipper Casein PF00363.18 CCU99712.1 - 0.25 11.7 2.7 1 9.8 1.0 2.9 2 0 0 2 2 2 0 Casein APOC4 PF15119.6 CCU99712.1 - 0.33 11.2 2.1 0.51 10.6 0.2 2.4 2 0 0 2 2 1 0 Apolipoprotein C4 DNA_ligase_A_M PF01068.21 CCU99713.1 - 7.1e-55 185.8 0.0 1.1e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CCU99713.1 - 1.3e-44 152.5 0.2 2.4e-44 151.7 0.2 1.4 1 0 0 1 1 1 1 DNA ligase N terminus eIF-3c_N PF05470.12 CCU99713.1 - 0.19 10.0 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Peptidase_M48_N PF16491.5 CCU99714.1 - 1.1e-51 175.3 2.8 2.4e-51 174.2 2.8 1.6 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CCU99714.1 - 3.2e-29 102.1 0.0 9.1e-29 100.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M48 SprT-like PF10263.9 CCU99714.1 - 0.11 12.4 0.9 0.22 11.4 0.1 1.9 2 0 0 2 2 2 0 SprT-like family GTP_EFTU PF00009.27 CCU99715.1 - 1e-57 194.8 0.0 1.7e-57 194.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CCU99715.1 - 1.9e-39 134.2 0.0 3.8e-39 133.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 CCU99715.1 - 3.8e-31 107.0 0.0 7.9e-31 106.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CCU99715.1 - 1.6e-23 82.5 0.1 3.6e-23 81.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCU99715.1 - 1.3e-12 47.9 0.0 3.7e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CCU99715.1 - 1.6e-05 24.7 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Sigma70_r3 PF04539.16 CCU99715.1 - 0.032 14.3 1.0 9.8 6.4 0.3 2.7 2 0 0 2 2 2 0 Sigma-70 region 3 TFIID-18kDa PF02269.16 CCU99716.1 - 1e-31 108.8 0.9 5.8e-28 96.8 0.6 2.4 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit SlyX PF04102.12 CCU99717.1 - 0.31 11.7 7.3 2.1 9.0 1.4 3.3 2 1 0 2 2 2 0 SlyX Peptidase_S46 PF10459.9 CCU99717.1 - 0.87 8.2 6.0 1.7 7.2 6.0 1.4 1 0 0 1 1 1 0 Peptidase S46 PLA2_B PF01735.18 CCU99718.1 - 7.1e-17 61.0 0.0 2e-08 33.1 0.1 3.1 3 0 0 3 3 3 3 Lysophospholipase catalytic domain OEP PF02321.18 CCU99718.1 - 0.19 11.5 0.1 0.38 10.5 0.1 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein Ribosomal_S10 PF00338.22 CCU99719.1 - 1e-24 86.6 0.0 1.5e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e BTB_2 PF02214.22 CCU99720.1 - 0.037 14.4 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain Longin PF13774.6 CCU99721.1 - 1.6e-23 82.6 0.0 2.2e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CCU99721.1 - 0.0002 21.1 0.2 0.0004 20.1 0.0 1.6 2 0 0 2 2 2 1 Synaptobrevin Septin PF00735.18 CCU99722.1 - 2e-108 362.0 0.0 2.6e-108 361.6 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CCU99722.1 - 1.5e-07 31.5 0.0 3.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CCU99722.1 - 6.3e-05 23.3 0.9 0.00069 19.9 0.1 2.8 2 2 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCU99722.1 - 0.00046 20.1 1.4 0.0032 17.4 0.2 2.8 3 1 0 3 3 3 1 RsgA GTPase Ras PF00071.22 CCU99722.1 - 0.00047 19.8 0.2 0.002 17.8 0.2 2.1 2 1 0 2 2 2 1 Ras family GTP_EFTU PF00009.27 CCU99722.1 - 0.00074 19.1 2.1 0.039 13.5 0.2 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CCU99722.1 - 0.002 18.6 1.3 0.0035 17.7 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 CCU99722.1 - 0.0029 17.8 0.0 0.0064 16.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CCU99722.1 - 0.0041 17.2 1.6 1.3 9.0 0.0 2.7 2 1 1 3 3 3 2 Dynamin family PduV-EutP PF10662.9 CCU99722.1 - 0.0095 15.7 0.2 0.6 9.8 0.2 2.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CCU99722.1 - 0.013 16.1 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AIG1 PF04548.16 CCU99722.1 - 0.021 14.2 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_24 PF13479.6 CCU99722.1 - 0.061 13.0 0.1 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCU99722.1 - 0.065 13.6 0.0 0.74 10.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Gtr1_RagA PF04670.12 CCU99722.1 - 0.065 12.6 0.0 0.36 10.2 0.0 2.2 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region AAA_28 PF13521.6 CCU99722.1 - 0.094 13.0 1.6 0.46 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 CCU99722.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4094 PF13334.6 CCU99722.1 - 0.21 12.0 0.7 0.52 10.8 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Casc1_N PF15927.5 CCU99722.1 - 0.23 11.1 8.7 0.47 10.1 8.7 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus SF3A2 PF16835.5 CCU99723.1 - 2.9e-34 117.3 0.0 4.8e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CCU99723.1 - 7.7e-07 29.3 1.1 1.5e-06 28.4 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Pyr_redox_2 PF07992.14 CCU99724.1 - 2.1e-09 37.0 0.0 7.4e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CCU99724.1 - 0.00083 19.4 5.0 0.0061 16.6 0.1 3.9 4 1 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CCU99724.1 - 0.0023 18.1 0.2 0.0084 16.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CCU99724.1 - 0.035 13.3 0.4 15 4.7 0.0 3.0 3 0 0 3 3 3 0 Thi4 family Pyr_redox PF00070.27 CCU99724.1 - 0.06 13.9 0.1 0.96 10.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCU99724.1 - 0.13 11.5 0.3 14 4.8 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PAS_7 PF12860.7 CCU99724.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 PAS fold K_oxygenase PF13434.6 CCU99724.1 - 0.2 10.7 0.9 8.2 5.5 0.0 2.7 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Ras PF00071.22 CCU99725.1 - 3e-54 183.0 0.0 3.4e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCU99725.1 - 4.3e-30 104.4 0.0 6.1e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU99725.1 - 1.2e-14 54.2 0.0 1.6e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCU99725.1 - 9.1e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CCU99725.1 - 8.7e-05 22.0 0.0 0.0001 21.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CCU99725.1 - 0.00025 21.0 0.0 0.018 14.9 0.0 2.5 2 1 1 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 CCU99725.1 - 0.003 18.0 0.3 0.0052 17.2 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCU99725.1 - 0.009 16.3 0.0 0.052 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CCU99725.1 - 0.0099 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) GTP_EFTU PF00009.27 CCU99725.1 - 0.012 15.1 0.0 0.03 13.9 0.0 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.14 CCU99725.1 - 0.026 14.5 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CCU99725.1 - 0.034 14.3 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CCU99725.1 - 0.04 13.6 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCU99725.1 - 0.046 13.5 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CCU99725.1 - 0.05 13.1 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region OmdA PF13376.6 CCU99725.1 - 0.093 12.8 0.6 0.22 11.6 0.6 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated TniB PF05621.11 CCU99725.1 - 0.094 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 CCU99725.1 - 0.23 10.9 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TruD PF01142.18 CCU99726.1 - 3e-72 243.7 0.0 1.5e-70 238.1 0.0 2.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Ammonium_transp PF00909.21 CCU99727.1 - 2.5e-111 372.2 21.2 2.8e-111 372.0 21.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family ENTH PF01417.20 CCU99728.1 - 3.4e-41 140.2 0.1 7.6e-41 139.1 0.1 1.6 1 1 0 1 1 1 1 ENTH domain ANTH PF07651.16 CCU99728.1 - 0.11 11.4 6.9 0.012 14.6 1.7 1.8 1 1 0 2 2 2 0 ANTH domain Hid1 PF12722.7 CCU99728.1 - 5.5 5.0 8.6 7.4 4.6 8.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Na_Ca_ex PF01699.24 CCU99729.1 - 2.3e-34 118.6 31.9 1.9e-18 66.9 14.9 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein AdenylateSensor PF16579.5 CCU99729.1 - 1.1e-13 51.7 0.0 1.2e-12 48.3 0.0 2.5 2 1 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase TPR_17 PF13431.6 CCU99730.1 - 0.0011 19.2 1.6 3.5 8.2 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat FAT PF02259.23 CCU99730.1 - 0.0026 17.0 0.2 1.3 8.1 0.0 3.4 3 0 0 3 3 3 2 FAT domain TPR_8 PF13181.6 CCU99730.1 - 0.013 15.7 1.6 28 5.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CCU99730.1 - 0.018 15.1 16.1 0.25 11.5 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 CCU99730.1 - 0.075 12.7 9.4 0.18 11.5 0.1 4.8 6 0 0 6 6 6 0 TPR repeat Tubulin PF00091.25 CCU99731.1 - 9.6e-71 238.1 0.0 2e-70 237.0 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CCU99731.1 - 1.4e-41 141.6 0.3 2.1e-41 141.0 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CCU99731.1 - 2.2e-06 28.0 0.0 5.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CCU99731.1 - 0.00053 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CCU99731.1 - 0.0067 15.7 0.0 0.021 14.1 0.0 1.7 2 0 0 2 2 2 1 Tubulin like Sacchrp_dh_C PF16653.5 CCU99732.1 - 8.1e-82 275.3 0.0 5e-81 272.7 0.0 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 CCU99732.1 - 6.2e-64 214.9 0.0 2e-63 213.2 0.0 1.8 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CCU99732.1 - 1.2e-22 79.5 0.0 2.4e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Sacchrp_dh_NADP PF03435.18 CCU99732.1 - 4e-22 78.9 0.2 1.7e-21 76.8 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CCU99732.1 - 3.3e-05 23.9 0.0 5.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_25 PF13649.6 CCU99732.1 - 0.0006 20.5 0.0 0.041 14.6 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 CCU99732.1 - 0.0018 17.6 0.1 0.0076 15.6 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.24 CCU99732.1 - 0.0027 18.1 0.0 0.011 16.2 0.0 2.1 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CCU99732.1 - 0.015 15.7 0.3 0.7 10.4 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.17 CCU99732.1 - 0.019 15.5 0.0 0.047 14.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CCU99732.1 - 0.035 14.2 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 CCU99732.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.12 CCU99732.1 - 0.096 13.4 0.2 2.3 9.0 0.1 3.0 2 1 0 2 2 2 0 Methyltransferase domain IlvN PF07991.12 CCU99732.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ank_2 PF12796.7 CCU99733.1 - 2.4e-29 101.7 0.3 6.8e-16 58.6 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CCU99733.1 - 6.3e-29 99.1 8.1 1.1e-08 35.1 0.3 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 CCU99733.1 - 1.7e-27 92.4 0.1 4e-06 26.8 0.1 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 CCU99733.1 - 1.6e-24 85.6 2.8 5.3e-08 33.0 0.3 4.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCU99733.1 - 6.8e-24 83.9 1.7 9.1e-08 32.5 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Glyoxalase_6 PF18029.1 CCU99733.1 - 0.021 15.6 4.4 2.4 9.0 0.2 2.6 2 1 1 3 3 3 0 Glyoxalase-like domain SQHop_cyclase_N PF13249.6 CCU99734.1 - 1.8e-53 181.5 3.3 6.9e-43 146.8 1.6 3.9 3 1 0 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 CCU99734.1 - 3.8e-44 151.1 0.6 5.5e-41 140.7 0.4 2.6 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 CCU99734.1 - 2.7e-32 110.2 4.0 1.1e-09 37.9 0.1 6.3 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 CCU99734.1 - 3.6e-06 26.2 0.0 0.0074 15.4 0.0 3.4 2 1 2 4 4 4 2 A-macroglobulin TED domain Pec_lyase PF09492.10 CCU99734.1 - 0.01 15.2 0.1 6.5 6.0 0.0 3.6 2 1 1 3 3 3 0 Pectic acid lyase Mago-bind PF09282.10 CCU99734.1 - 0.029 14.3 2.8 2.8 7.9 0.0 2.7 3 0 0 3 3 3 0 Mago binding Pex16 PF08610.10 CCU99735.1 - 5.9e-111 370.7 1.8 7.1e-111 370.5 1.8 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) ATG13 PF10033.9 CCU99736.1 - 2.1e-38 132.4 0.0 5.4e-38 131.0 0.0 1.7 1 1 0 1 1 1 1 Autophagy-related protein 13 Pkinase PF00069.25 CCU99737.1 - 3e-58 197.3 0.0 3.9e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99737.1 - 1.2e-36 126.3 0.0 7.3e-35 120.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU99737.1 - 1.2e-07 31.3 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCU99737.1 - 0.0012 18.9 0.0 0.17 11.8 0.0 3.3 3 1 1 4 4 4 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCU99737.1 - 0.028 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 CCU99737.1 - 0.039 13.0 0.1 0.061 12.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 CCU99737.1 - 0.048 12.6 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Glyco_transf_22 PF03901.17 CCU99738.1 - 6.1e-66 223.4 16.3 5.5e-45 154.3 11.3 2.2 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family NatB_MDM20 PF09797.9 CCU99738.1 - 1.7e-43 149.0 0.0 1.2e-32 113.3 0.1 2.3 1 1 1 2 2 2 2 N-acetyltransferase B complex (NatB) non catalytic subunit ERCC4 PF02732.15 CCU99739.1 - 1.3e-15 57.9 0.0 1.8e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 ERCC4 domain SIR2 PF02146.17 CCU99740.1 - 6.2e-21 75.1 0.0 3.1e-20 72.8 0.0 1.9 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CCU99740.1 - 0.018 14.8 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain DUF364 PF04016.12 CCU99740.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative heavy-metal chelation zf-ribbon_3 PF13248.6 CCU99740.1 - 0.12 11.9 1.1 0.19 11.2 0.2 1.8 2 0 0 2 2 2 0 zinc-ribbon domain PRA1 PF03208.19 CCU99741.1 - 4e-33 114.1 3.3 4.9e-33 113.8 3.3 1.0 1 0 0 1 1 1 1 PRA1 family protein Telomerase_RBD PF12009.8 CCU99742.1 - 2.1e-33 115.3 3.5 3.7e-33 114.5 3.5 1.4 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CCU99742.1 - 7.2e-12 45.3 0.0 2.1e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 CCU99743.1 - 2.1e-61 202.4 13.9 1.6e-06 28.7 0.0 11.9 11 1 1 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.11 CCU99743.1 - 2.8e-52 176.4 1.2 4.5e-52 175.7 1.2 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 CCU99743.1 - 1.1e-13 51.3 0.5 0.11 12.8 0.0 7.0 4 3 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCU99743.1 - 1.3e-13 50.5 4.6 3.1e-05 22.8 0.1 6.6 3 2 1 7 7 7 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CCU99743.1 - 0.00011 21.1 0.0 0.35 9.5 0.0 4.1 4 0 0 4 4 4 1 Nup133 N terminal like Ge1_WD40 PF16529.5 CCU99743.1 - 0.00048 19.2 1.2 1.8 7.4 0.0 4.7 2 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SIP PF04954.13 CCU99743.1 - 0.0031 18.0 1.8 0.04 14.4 0.4 2.7 2 0 0 2 2 2 1 Siderophore-interacting protein WD40_like PF17005.5 CCU99743.1 - 0.0061 15.9 0.0 0.26 10.6 0.0 3.1 3 1 0 3 3 3 1 WD40-like domain PALB2_WD40 PF16756.5 CCU99743.1 - 0.088 11.7 1.1 1.4 7.7 0.1 2.5 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Se-cys_synth_N PF12390.8 CCU99743.1 - 0.089 13.0 0.5 0.34 11.2 0.5 2.0 1 0 0 1 1 1 0 Selenocysteine synthase N terminal SF3b1 PF08920.10 CCU99744.1 - 3.8e-17 62.9 8.1 8.6e-14 52.1 0.0 3.9 1 1 2 3 3 3 3 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 CCU99744.1 - 5.4e-16 58.8 14.7 0.00051 20.4 0.3 9.2 4 3 3 9 9 9 4 HEAT repeats HEAT_EZ PF13513.6 CCU99744.1 - 9.3e-11 42.0 11.4 0.01 16.4 0.0 8.0 7 1 1 8 8 7 2 HEAT-like repeat HEAT PF02985.22 CCU99744.1 - 2.1e-07 30.6 11.3 2.8 8.4 0.0 10.0 11 0 0 11 11 10 2 HEAT repeat Adaptin_N PF01602.20 CCU99744.1 - 2.9e-06 26.1 0.1 0.08 11.5 0.1 3.4 2 1 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 CCU99744.1 - 1.2e-05 25.5 4.6 0.29 11.2 0.0 5.7 4 2 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CCU99744.1 - 9.6e-05 22.9 0.3 19 5.9 0.0 5.2 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 CCU99744.1 - 0.00015 21.0 0.1 0.013 14.7 0.0 3.1 2 1 0 3 3 3 1 Dopey, N-terminal CLASP_N PF12348.8 CCU99744.1 - 0.00019 21.1 2.3 0.074 12.6 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal NUC173 PF08161.12 CCU99744.1 - 0.00022 21.0 1.3 1.2 8.7 0.0 4.3 4 2 1 5 5 5 2 NUC173 domain MMS19_C PF12460.8 CCU99744.1 - 0.0017 17.6 0.0 8.8 5.3 0.0 4.0 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 CCU99744.1 - 0.0053 16.7 0.1 5 7.0 0.1 3.9 3 2 0 3 3 3 1 Domain of unknown function (DUF3385) DUF3730 PF12530.8 CCU99744.1 - 0.018 14.6 0.1 0.089 12.3 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3730) UNC45-central PF11701.8 CCU99744.1 - 0.2 11.6 0.1 3.7 7.5 0.0 2.7 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central RRM_1 PF00076.22 CCU99746.1 - 0.0073 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 CCU99746.1 - 0.13 13.1 0.0 0.24 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II-binding domain. Ribosomal_S2 PF00318.20 CCU99747.1 - 8.5e-28 97.1 0.2 4.1e-14 52.3 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CCU99747.1 - 9.7e-12 46.1 7.4 1.6e-11 45.4 7.4 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S11 PF00411.19 CCU99747.1 - 0.14 12.6 1.4 0.39 11.1 1.4 1.8 1 0 0 1 1 1 0 Ribosomal protein S11 Ribosomal_S5 PF00333.20 CCU99748.1 - 1.4e-28 98.7 1.1 3.2e-28 97.5 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CCU99748.1 - 5e-23 80.4 0.0 8.3e-23 79.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain F1F0-ATPsyn_F PF10791.9 CCU99749.1 - 1.6e-27 95.8 0.1 2.9e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi BRO1 PF03097.18 CCU99749.1 - 5.5e-18 65.0 0.0 7.9e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain NAP PF00956.18 CCU99750.1 - 3.6e-89 298.5 0.2 4.8e-89 298.1 0.2 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) E7 PF00527.18 CCU99750.1 - 0.092 13.0 0.6 0.092 13.0 0.6 2.8 3 0 0 3 3 3 0 E7 protein, Early protein RNA_pol_3_Rpc31 PF11705.8 CCU99750.1 - 1.3 9.3 23.8 0.6 10.3 12.7 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Vps53_N PF04100.12 CCU99751.1 - 3.3e-70 237.0 0.0 4.8e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2451 PF10474.9 CCU99751.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) KH_6 PF15985.5 CCU99752.1 - 1.3e-08 35.0 0.0 2.1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 CCU99752.1 - 1.2e-06 28.3 0.0 2.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain ETC_C1_NDUFA4 PF04800.12 CCU99753.1 - 2.2e-35 120.8 0.1 2.9e-35 120.4 0.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region ATP_bind_1 PF03029.17 CCU99754.1 - 2.1e-41 142.3 0.0 7.1e-37 127.5 0.0 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein HSA PF07529.13 CCU99756.1 - 5.9e-12 45.7 1.6 5.9e-12 45.7 1.6 3.9 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.6 CCU99756.1 - 0.0001 22.5 2.5 0.00024 21.3 2.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 CCU99756.1 - 0.052 13.7 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 CCU99756.1 - 0.063 13.5 0.9 0.15 12.2 0.9 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Pol_alpha_B_N PF08418.10 CCU99756.1 - 6 6.7 13.8 1.4 8.8 7.6 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal SpoIIE PF07228.12 CCU99757.1 - 5.7e-10 39.4 0.0 3.7e-08 33.5 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CCU99757.1 - 7.5e-08 32.3 0.2 1.3e-07 31.4 0.2 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CCU99757.1 - 5.2e-07 29.5 0.0 0.0013 18.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Isochorismatase PF00857.20 CCU99758.1 - 4e-21 76.0 1.0 1.7e-20 74.0 1.0 1.9 1 1 0 1 1 1 1 Isochorismatase family TRP_N PF14558.6 CCU99759.1 - 3.3e-24 85.8 0.4 6.6e-24 84.9 0.1 1.6 2 0 0 2 2 2 1 ML-like domain TRP PF06011.12 CCU99759.1 - 6.1e-21 74.6 5.4 8.8e-21 74.1 5.4 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel KH_1 PF00013.29 CCU99760.1 - 2e-74 245.3 0.0 2.8e-14 52.7 0.2 11.4 11 0 0 11 11 11 9 KH domain KH_2 PF07650.17 CCU99760.1 - 1.1e-08 34.7 2.5 0.084 12.7 0.1 6.2 7 0 0 7 7 7 3 KH domain KH_4 PF13083.6 CCU99760.1 - 7e-06 25.8 0.8 9.5 6.2 0.0 6.2 6 0 0 6 6 6 2 KH domain SLS PF14611.6 CCU99760.1 - 0.028 14.2 0.6 0.95 9.2 0.1 3.4 4 1 1 5 5 5 0 Mitochondrial inner-membrane-bound regulator MFS_1 PF07690.16 CCU99761.1 - 6.2e-16 58.3 40.2 7.7e-12 44.8 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCU99761.1 - 1.5e-07 30.7 20.5 3.8e-07 29.3 9.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter WD40 PF00400.32 CCU99762.1 - 1.3e-10 41.7 7.0 7.2e-05 23.5 0.2 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 CCU99762.1 - 0.36 11.4 0.0 0.36 11.4 0.0 5.3 5 0 0 5 5 5 0 PQQ-like domain Metallophos PF00149.28 CCU99763.1 - 2e-11 44.8 1.5 3.9e-11 43.9 1.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TetR_C_11 PF16859.5 CCU99763.1 - 0.87 9.9 3.2 5.8 7.3 0.0 3.4 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Metallophos PF00149.28 CCU99764.1 - 8e-13 49.4 4.8 1.3e-12 48.6 3.9 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 CCU99765.1 - 4e-08 34.0 2.5 6e-08 33.4 2.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF836 PF05768.14 CCU99766.1 - 9.6e-12 45.2 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 CCU99766.1 - 0.0066 16.9 0.1 0.0089 16.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CCU99766.1 - 0.039 13.9 0.0 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family TraF PF13728.6 CCU99766.1 - 0.077 12.8 0.0 0.092 12.6 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein SUR7 PF06687.12 CCU99767.1 - 1.4e-07 31.3 4.3 3.5e-07 30.1 4.3 1.6 1 1 0 1 1 1 1 SUR7/PalI family Trp_oprn_chp PF09534.10 CCU99767.1 - 2 8.2 15.9 4.9 6.9 15.9 1.6 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) COPI_assoc PF08507.10 CCU99767.1 - 2 8.5 4.7 8.2 6.5 4.7 1.9 1 1 0 1 1 1 0 COPI associated protein tRNA-synt_1 PF00133.22 CCU99768.1 - 8.5e-39 133.3 0.0 2.2e-30 105.5 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CCU99768.1 - 2.3e-14 53.0 0.0 5.9e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CCU99768.1 - 3.3e-14 53.1 0.0 8.2e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CCU99768.1 - 2.1e-06 27.3 0.0 3.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF3224 PF11528.8 CCU99768.1 - 0.056 13.2 0.4 0.2 11.5 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3224) Med12 PF09497.10 CCU99769.1 - 9.3e-25 86.7 0.1 3.2e-24 85.0 0.0 2.1 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 CCU99769.1 - 0.052 12.4 0.7 0.34 9.7 0.4 2.0 2 0 0 2 2 2 0 Eukaryotic Mediator 12 subunit domain ARPC4 PF05856.12 CCU99770.1 - 1.6e-76 255.5 3.1 1.9e-76 255.4 3.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) SNF2_N PF00176.23 CCU99771.1 - 9.5e-60 202.1 0.1 1.5e-59 201.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 CCU99771.1 - 7.2e-26 90.5 0.3 2.4e-25 88.8 0.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 CCU99771.1 - 9.4e-19 67.8 0.0 2.3e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 CCU99771.1 - 4.3e-15 55.4 0.0 1.4e-09 37.7 0.0 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 CCU99771.1 - 1.4e-08 34.9 0.0 8.1e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 CCU99771.1 - 2.8e-06 27.6 0.2 2.8e-06 27.6 0.2 5.1 5 1 1 6 6 6 1 Chromodomain helicase DNA-binding domain 1 DEAD PF00270.29 CCU99771.1 - 0.0022 17.8 0.0 0.0063 16.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Med9 PF07544.13 CCU99771.1 - 0.52 10.4 4.1 0.19 11.8 0.1 2.4 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 MMR_HSR1 PF01926.23 CCU99772.1 - 2.7e-15 56.4 0.1 1.2e-12 47.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CCU99772.1 - 7e-09 35.4 0.1 0.00011 21.8 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 CCU99772.1 - 1.1e-05 25.1 0.1 0.001 18.7 0.0 2.7 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCU99772.1 - 3e-05 24.0 0.6 0.066 13.1 0.3 2.3 1 1 1 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 CCU99772.1 - 0.01 15.9 1.5 0.49 10.4 0.2 2.8 2 1 1 3 3 3 0 Dynamin family CDC27 PF09507.10 CCU99772.1 - 8.1 5.7 10.3 4.6 6.5 7.9 1.5 1 1 1 2 2 2 0 DNA polymerase subunit Cdc27 PALP PF00291.25 CCU99773.1 - 1.1e-77 261.3 1.9 1.4e-77 261.0 1.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 CCU99773.1 - 7e-39 131.5 0.0 2.3e-21 75.4 0.0 3.3 3 0 0 3 3 3 3 C-terminal regulatory domain of Threonine dehydratase ABC_membrane PF00664.23 CCU99774.1 - 5.4e-92 308.3 20.0 3.4e-48 164.7 3.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCU99774.1 - 6.3e-60 201.6 0.0 1.1e-29 103.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCU99774.1 - 5.6e-11 42.3 0.7 0.0036 16.8 0.0 3.8 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CCU99774.1 - 8.4e-07 29.3 2.2 0.67 10.2 0.0 4.4 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CCU99774.1 - 5.6e-06 26.8 4.4 0.0073 16.7 0.3 3.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CCU99774.1 - 9e-06 25.3 0.5 0.11 12.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 CCU99774.1 - 1.9e-05 24.5 0.6 0.0074 16.0 0.2 3.3 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 CCU99774.1 - 0.0024 17.5 2.2 2.1 7.9 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 CCU99774.1 - 0.0028 17.8 0.1 1.1 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 CCU99774.1 - 0.0032 16.3 0.1 0.072 11.9 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DUF87 PF01935.17 CCU99774.1 - 0.0035 17.5 0.5 1.2 9.2 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 CCU99774.1 - 0.0056 16.6 0.0 4.4 7.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase SbcCD_C PF13558.6 CCU99774.1 - 0.0083 16.3 5.4 2 8.7 0.4 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 CCU99774.1 - 0.0085 15.8 0.0 0.78 9.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 CCU99774.1 - 0.011 16.3 2.7 0.77 10.3 0.1 3.0 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 CCU99774.1 - 0.012 14.6 0.0 0.06 12.3 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 CCU99774.1 - 0.024 13.8 0.0 4.9 6.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit PRK PF00485.18 CCU99774.1 - 0.048 13.4 1.7 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 CCU99774.1 - 0.14 11.8 2.1 17 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain Tex_YqgF PF16921.5 CCU99774.1 - 0.15 12.5 0.2 1.4 9.4 0.1 2.3 2 0 0 2 2 2 0 Tex protein YqgF-like domain AAA_28 PF13521.6 CCU99774.1 - 0.17 12.1 0.4 12 6.1 0.1 2.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CCU99774.1 - 0.23 11.6 0.2 18 5.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CCU99774.1 - 0.28 11.0 3.7 7.4 6.3 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AMP-binding PF00501.28 CCU99775.1 - 9e-207 686.7 3.8 3.9e-76 256.4 0.0 3.6 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 CCU99775.1 - 3.4e-59 200.7 0.0 3.1e-21 75.6 0.0 6.7 5 2 0 5 5 5 5 Condensation domain PP-binding PF00550.25 CCU99775.1 - 3e-41 139.6 5.6 6.2e-13 48.9 0.1 5.3 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 CCU99775.1 - 6.3e-14 52.7 4.8 0.0024 18.8 0.1 5.0 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain DEAD PF00270.29 CCU99776.1 - 3.4e-41 140.9 0.0 5.9e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU99776.1 - 1.8e-22 79.8 0.0 6.1e-22 78.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CCU99776.1 - 5.2e-18 65.1 0.3 1.3e-17 63.8 0.3 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 CCU99776.1 - 0.0001 22.4 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Metallophos PF00149.28 CCU99778.1 - 4.1e-27 96.0 0.0 5.9e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Put_Phosphatase PF06888.12 CCU99779.1 - 9.3e-51 172.5 0.0 1.2e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 CCU99779.1 - 3.4e-05 24.3 0.1 0.00012 22.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MIase PF02426.16 CCU99779.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Muconolactone delta-isomerase RhoGEF PF00621.20 CCU99780.1 - 3.4e-14 53.5 0.0 4.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 RhoGEF domain DUF3141 PF11339.8 CCU99780.1 - 0.031 12.7 0.0 0.25 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3141) LysM PF01476.20 CCU99782.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 LysM domain MmgE_PrpD PF03972.14 CCU99783.1 - 6.6e-154 512.7 0.8 7.4e-154 512.5 0.8 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PALP PF00291.25 CCU99784.1 - 1.2e-66 225.1 0.1 1.4e-66 224.9 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.25 CCU99785.1 - 9.7e-53 179.2 0.0 1.5e-52 178.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99785.1 - 1.5e-21 76.9 0.0 2.4e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCU99785.1 - 0.0019 18.1 0.1 0.0019 18.1 0.1 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CCU99785.1 - 0.013 15.1 0.2 0.026 14.1 0.2 1.5 1 0 0 1 1 1 0 RIO1 family NUDE_C PF04880.13 CCU99786.1 - 1.2e-10 42.2 4.2 1.2e-10 42.2 4.2 4.4 2 2 4 6 6 4 1 NUDE protein, C-terminal conserved region AKNA PF12443.8 CCU99786.1 - 0.032 14.9 10.4 0.046 14.4 1.1 3.7 3 1 0 3 3 3 0 AT-hook-containing transcription factor CCDC92 PF14916.6 CCU99786.1 - 0.094 12.5 0.3 0.094 12.5 0.3 2.5 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DUF3584 PF12128.8 CCU99786.1 - 0.18 9.3 28.6 0.058 10.9 23.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 CCU99786.1 - 0.37 10.2 28.3 0.042 13.3 12.0 2.8 2 1 1 3 3 3 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 CCU99786.1 - 0.37 10.8 31.8 0.082 13.0 7.1 4.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein AIP3 PF03915.13 CCU99786.1 - 0.39 9.8 13.1 0.072 12.2 6.5 2.2 1 1 1 2 2 2 0 Actin interacting protein 3 FlaC_arch PF05377.11 CCU99786.1 - 0.4 11.1 8.8 7.3 7.1 0.0 4.2 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) PRKG1_interact PF15898.5 CCU99786.1 - 0.41 11.6 28.1 0.06 14.3 10.3 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 CCU99786.1 - 1 9.8 34.6 6.2 7.3 12.7 4.8 1 1 2 3 3 3 0 Cell division protein ZapB YabA PF06156.13 CCU99786.1 - 2.8 8.6 21.3 4.1 8.1 6.5 3.9 2 1 2 4 4 4 0 Initiation control protein YabA Rx_N PF18052.1 CCU99786.1 - 3.5 8.0 16.8 21 5.4 0.0 4.6 3 1 1 4 4 4 0 Rx N-terminal domain Peptidase_S46 PF10459.9 CCU99786.1 - 3.9 6.0 14.7 5.6 5.5 14.7 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF4407 PF14362.6 CCU99786.1 - 5.1 6.4 19.7 3.7 6.8 10.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.15 CCU99786.1 - 6.8 6.9 20.4 2.7 8.1 0.5 5.0 4 2 1 5 5 5 0 Basic region leucine zipper DMPK_coil PF08826.10 CCU99786.1 - 7.4 6.8 26.8 1.2 9.3 0.3 5.0 3 2 2 5 5 5 0 DMPK coiled coil domain like Fib_alpha PF08702.10 CCU99786.1 - 8.2 6.6 9.7 2.4 8.4 3.1 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family HALZ PF02183.18 CCU99786.1 - 8.7 6.7 17.3 1.9 8.8 0.2 4.4 5 0 0 5 5 5 0 Homeobox associated leucine zipper CAP_GLY PF01302.25 CCU99787.1 - 3.5e-13 49.3 0.2 5.4e-13 48.7 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain Filament PF00038.21 CCU99787.1 - 0.54 9.8 51.0 0.023 14.3 11.1 4.2 2 1 2 4 4 4 0 Intermediate filament protein Gp-FAR-1 PF05823.12 CCU99787.1 - 0.98 9.8 5.6 3.1 8.2 3.6 2.3 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) GIT_CC PF16559.5 CCU99787.1 - 7.1 6.6 13.8 0.22 11.4 0.2 4.0 4 2 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Mvb12 PF09452.10 CCU99787.1 - 7.2 7.1 10.0 1.6 9.2 0.1 3.8 4 1 1 5 5 5 0 ESCRT-I subunit Mvb12 EHN PF06441.12 CCU99787.1 - 9.4 6.7 8.4 22 5.5 1.3 3.6 3 1 0 3 3 3 0 Epoxide hydrolase N terminus GN3L_Grn1 PF08701.11 CCU99788.1 - 7.7e-22 77.2 14.9 7.7e-22 77.2 14.9 2.6 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase Nop14 PF04147.12 CCU99788.1 - 0.00066 18.1 27.1 0.00066 18.1 27.1 2.2 2 0 0 2 2 2 1 Nop14-like family BUD22 PF09073.10 CCU99788.1 - 0.028 13.8 42.2 0.058 12.7 30.8 2.3 2 0 0 2 2 2 0 BUD22 Proteasome PF00227.26 CCU99789.1 - 5e-38 130.5 0.0 6.6e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit EF-hand_1 PF00036.32 CCU99790.1 - 3.2e-22 76.4 12.9 3.6e-07 29.3 1.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CCU99790.1 - 8.1e-20 71.0 11.0 3.7e-12 46.5 1.6 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CCU99790.1 - 1.7e-19 68.0 7.4 7.7e-05 22.3 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CCU99790.1 - 2e-15 55.5 12.9 0.00015 21.1 0.8 4.5 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CCU99790.1 - 2.2e-11 43.4 10.7 0.0017 18.2 0.4 3.6 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CCU99790.1 - 0.00014 22.1 0.1 0.03 14.6 0.0 2.4 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CCU99790.1 - 0.00057 19.8 5.6 1.1 9.2 0.4 3.7 1 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CCU99790.1 - 0.0048 17.1 2.3 0.11 12.7 1.7 3.0 2 2 0 2 2 2 1 Dockerin type I domain EF-hand_9 PF14658.6 CCU99790.1 - 0.0049 17.2 0.1 5.6 7.4 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain DUF465 PF04325.13 CCU99790.1 - 0.052 13.6 0.6 0.17 12.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Ribosomal_S13 PF00416.22 CCU99791.1 - 1.6e-19 70.5 0.0 4.1e-09 36.9 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein S13/S18 FbpA PF05833.11 CCU99791.1 - 0.001 17.9 0.0 0.0015 17.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) AMP-binding PF00501.28 CCU99792.1 - 1.2e-50 172.3 0.0 2.1e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CCU99792.1 - 2e-08 34.0 0.1 5e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 CCU99792.1 - 0.17 12.9 0.2 1.2 10.1 0.1 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Gar1 PF04410.14 CCU99793.1 - 9.8e-35 119.6 0.0 1.2e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Vps26 PF03643.15 CCU99795.1 - 1.3e-53 181.8 0.2 1.4e-53 181.7 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Glyco_tranf_2_3 PF13641.6 CCU99796.1 - 7.7e-15 55.4 0.0 1.2e-14 54.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CCU99796.1 - 8.7e-12 45.4 2.7 3e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CCU99796.1 - 2.9e-06 27.2 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CCU99796.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Topoisom_I PF01028.20 CCU99797.1 - 1.1e-74 250.6 0.0 1.1e-74 250.6 0.0 2.4 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CCU99797.1 - 6.5e-73 244.8 0.2 6.5e-73 244.8 0.2 3.4 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 CCU99797.1 - 2.3e-16 59.5 4.4 5.1e-13 48.7 0.2 3.6 3 0 0 3 3 3 2 C-terminal topoisomerase domain WHAMM-JMY_N PF15920.5 CCU99797.1 - 0.0081 16.0 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 N-terminal of Junction-mediating and WASP homolog-associated Sporozoite_P67 PF05642.11 CCU99797.1 - 5.4 5.0 13.2 10 4.1 13.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PAS PF00989.25 CCU99798.1 - 5.5e-05 23.1 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold Adenyl_transf PF04439.12 CCU99798.1 - 0.034 13.3 0.1 0.052 12.7 0.1 1.2 1 0 0 1 1 1 0 Streptomycin adenylyltransferase Forkhead_N PF08430.12 CCU99798.1 - 0.2 12.2 2.6 0.16 12.5 0.7 1.7 1 1 0 1 1 1 0 Forkhead N-terminal region PEPCK_ATP PF01293.20 CCU99799.1 - 1e-203 677.3 0.0 7.8e-203 674.3 0.0 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 CCU99799.1 - 0.077 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain MPC PF03650.13 CCU99800.1 - 1.2e-30 105.9 0.2 1.3e-30 105.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Mg_trans_NIPA PF05653.14 CCU99801.1 - 6.6e-90 301.2 29.0 9.2e-90 300.7 29.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CCU99801.1 - 0.0001 22.5 7.7 0.0001 22.5 7.7 3.4 3 1 0 3 3 3 1 EamA-like transporter family PP2C PF00481.21 CCU99802.1 - 6.5e-43 147.2 0.0 2.6e-42 145.2 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 CCU99802.1 - 1.5e-41 139.6 41.5 5.3e-05 23.5 0.1 11.7 6 3 4 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCU99802.1 - 2.8e-38 129.5 48.6 7.1e-08 32.1 2.3 9.6 5 3 6 11 11 11 9 Leucine rich repeat Guanylate_cyc PF00211.20 CCU99802.1 - 2.8e-26 92.3 0.0 5.2e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 CCU99802.1 - 1.4e-07 31.2 12.2 0.028 13.9 0.1 4.5 2 1 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 CCU99802.1 - 0.0055 17.1 35.5 9.3 7.2 0.0 13.6 15 1 0 15 15 15 2 Leucine Rich Repeat LRR_6 PF13516.6 CCU99802.1 - 2.1 8.6 33.6 15 5.9 0.0 11.4 14 0 0 14 14 14 0 Leucine Rich repeat Mito_carr PF00153.27 CCU99803.1 - 3.8e-44 148.6 6.6 1.5e-17 63.3 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ATP-sulfurylase PF01747.17 CCU99804.1 - 1.7e-87 292.4 0.0 2.4e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 CCU99804.1 - 3e-57 192.9 0.0 4.4e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 CCU99804.1 - 2.2e-51 173.7 0.0 3.5e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain CTP_transf_like PF01467.26 CCU99804.1 - 0.064 13.4 0.0 0.45 10.7 0.0 2.3 2 1 0 2 2 2 0 Cytidylyltransferase-like CBFD_NFYB_HMF PF00808.23 CCU99805.1 - 5.7e-08 32.9 0.1 2.9e-07 30.7 0.1 2.2 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ku PF02735.16 CCU99806.1 - 7.1e-41 140.1 0.0 1.1e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CCU99806.1 - 8.8e-09 35.4 0.0 1.7e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CCU99806.1 - 7.2e-08 33.0 0.3 2.1e-07 31.5 0.3 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm adh_short_C2 PF13561.6 CCU99807.1 - 1.2e-43 149.4 0.2 1.4e-43 149.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CCU99807.1 - 3.4e-39 134.3 0.4 4.3e-39 134.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CCU99807.1 - 2.3e-10 40.7 0.2 3.4e-10 40.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CCU99807.1 - 0.036 13.2 0.1 0.052 12.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_L39 PF00832.20 CCU99808.1 - 8.2e-21 73.4 10.8 1e-20 73.1 10.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Nmad3 PF18754.1 CCU99808.1 - 0.012 15.2 0.3 0.012 15.2 0.3 1.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 WD40 PF00400.32 CCU99810.1 - 7.6e-37 124.7 15.8 2.5e-07 31.3 0.0 8.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU99810.1 - 1.4e-19 70.1 0.0 2.7e-07 30.8 0.0 6.3 4 3 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCU99810.1 - 1.9e-07 30.4 5.3 0.047 12.7 0.1 5.3 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CCU99810.1 - 1e-05 25.0 0.1 0.14 11.4 0.0 3.6 3 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.6 CCU99810.1 - 0.016 14.5 0.0 14 4.8 0.0 3.9 5 0 0 5 5 5 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 CCU99810.1 - 0.038 12.6 1.5 0.11 11.2 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 TFIIIC_delta PF12657.7 CCU99810.1 - 0.14 12.1 1.4 20 5.0 0.2 3.1 2 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term PQQ PF01011.21 CCU99810.1 - 0.17 11.8 5.3 11 6.2 0.3 4.3 4 0 0 4 4 4 0 PQQ enzyme repeat DUF3684 PF12449.8 CCU99811.1 - 0 1102.4 0.0 0 1102.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Diphthamide_syn PF01866.17 CCU99811.1 - 8.8e-80 268.4 0.0 1.6e-79 267.5 0.0 1.5 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TPR_1 PF00515.28 CCU99811.1 - 4.6e-19 67.4 2.9 0.00013 21.7 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CCU99811.1 - 1.9e-14 52.5 6.8 0.0057 16.7 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 CCU99811.1 - 2.4e-12 47.3 5.4 0.0022 18.6 0.0 6.6 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCU99811.1 - 2.5e-12 46.3 0.3 0.00049 19.7 0.0 5.1 4 1 1 5 5 5 3 TPR repeat TPR_8 PF13181.6 CCU99811.1 - 4.4e-10 39.0 1.9 0.012 15.8 0.0 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCU99811.1 - 2.6e-09 36.4 5.3 0.23 11.6 0.0 5.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CCU99811.1 - 2.2e-08 34.2 13.1 0.031 15.1 0.0 7.5 6 2 1 7 7 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CCU99811.1 - 1.6e-07 31.7 6.5 0.011 16.2 0.7 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCU99811.1 - 1.3e-05 25.4 5.8 7.4e-05 23.0 0.0 4.5 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCU99811.1 - 3.6e-05 23.9 2.1 0.58 10.7 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CCU99811.1 - 0.0024 17.7 4.5 0.13 12.2 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 CCU99811.1 - 0.0043 17.2 3.1 4.1 7.6 0.0 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 CCU99811.1 - 0.0093 16.3 14.8 0.2 12.0 1.0 5.8 3 1 2 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCU99811.1 - 0.038 14.2 6.1 1.6 9.0 0.5 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CCU99811.1 - 0.16 12.7 0.8 74 4.3 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat MRC1 PF09444.10 CCU99812.1 - 5.4e-31 108.1 21.5 5.4e-31 108.1 21.5 2.7 2 1 0 2 2 2 1 MRC1-like domain tRNA-synt_1b PF00579.25 CCU99813.1 - 1.4e-22 80.4 0.0 1.6e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Tim17 PF02466.19 CCU99814.1 - 5.2e-30 104.1 6.0 6.9e-30 103.7 6.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ATP-synt_DE_N PF02823.16 CCU99815.1 - 3.1e-16 59.0 0.1 4.9e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ABC_membrane_2 PF06472.15 CCU99816.1 - 9.2e-66 222.0 2.6 1.2e-65 221.6 2.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CCU99816.1 - 8.6e-20 71.6 0.0 2.1e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CCU99816.1 - 0.0034 17.2 0.0 0.007 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCU99816.1 - 0.0067 15.9 0.0 0.19 11.2 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain PBAN PF05874.11 CCU99816.1 - 0.016 15.1 0.1 0.038 13.9 0.0 1.6 2 0 0 2 2 2 0 Pheromone biosynthesis activating neuropeptide (PBAN) Rad17 PF03215.15 CCU99816.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 CCU99816.1 - 0.046 14.2 0.2 0.52 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CCU99816.1 - 0.049 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cloacin_immun PF03513.14 CCU99816.1 - 0.08 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Cloacin immunity protein SecY PF00344.20 CCU99817.1 - 4.2e-71 239.7 11.8 5.4e-71 239.3 11.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CCU99817.1 - 7.3e-17 60.9 0.3 1.8e-16 59.6 0.3 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p RseC_MucC PF04246.12 CCU99817.1 - 9.5 6.2 6.0 1.3 9.0 0.3 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC BRE1 PF08647.11 CCU99819.1 - 8.9e-24 83.4 41.6 1.8e-23 82.4 9.5 5.7 5 1 0 5 5 5 3 BRE1 E3 ubiquitin ligase Lebercilin PF15619.6 CCU99819.1 - 0.00014 21.6 15.6 0.00014 21.6 15.6 5.4 3 2 1 5 5 5 2 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 CCU99819.1 - 0.00035 21.1 57.7 0.085 13.3 7.5 4.4 1 1 3 4 4 4 3 Fez1 MscS_porin PF12795.7 CCU99819.1 - 0.007 15.9 8.3 0.007 15.9 8.3 4.6 2 1 2 4 4 4 3 Mechanosensitive ion channel porin domain TraF_2 PF13729.6 CCU99819.1 - 0.73 9.2 6.9 0.79 9.0 0.8 3.1 2 1 1 3 3 3 0 F plasmid transfer operon, TraF, protein ATG16 PF08614.11 CCU99819.1 - 7.4 6.7 91.0 0.2 11.9 8.5 5.8 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) Pyridoxal_deC PF00282.19 CCU99820.1 - 4.8e-22 78.2 0.0 8e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CCU99820.1 - 2.3e-08 33.4 0.0 4.2e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CCU99820.1 - 0.048 13.0 0.3 0.092 12.0 0.1 1.4 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family TFIIA PF03153.13 CCU99821.1 - 4.4e-52 178.5 15.5 5.3e-32 112.3 13.6 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 CCU99821.1 - 0.014 15.2 3.1 0.014 15.1 3.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 CCU99821.1 - 8.2 4.4 8.8 11 4.0 8.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Med26 PF08711.11 CCU99822.1 - 3.5e-07 30.2 0.0 7.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PWWP PF00855.17 CCU99822.1 - 0.027 14.9 0.0 0.11 13.0 0.0 2.1 1 1 0 1 1 1 0 PWWP domain DUF2052 PF09747.9 CCU99822.1 - 0.078 13.1 8.6 0.11 12.6 8.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4611 PF15387.6 CCU99822.1 - 0.12 12.6 7.8 0.26 11.5 7.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 CCU99822.1 - 0.48 8.7 7.9 0.53 8.5 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Hamartin PF04388.12 CCU99823.1 - 4.4e-06 25.7 1.8 4.4e-06 25.7 1.8 2.3 1 1 0 2 2 2 1 Hamartin protein CLZ PF16526.5 CCU99823.1 - 0.019 15.3 1.2 0.019 15.3 1.2 4.1 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3135 PF11333.8 CCU99823.1 - 0.083 13.2 3.7 0.093 13.0 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) IFT57 PF10498.9 CCU99823.1 - 0.64 8.9 15.2 0.7 8.8 7.2 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 AAA_13 PF13166.6 CCU99823.1 - 1.8 7.1 9.2 2.9 6.4 9.2 1.2 1 0 0 1 1 1 0 AAA domain EMP70 PF02990.16 CCU99824.1 - 2.4e-182 607.2 0.0 4.1e-182 606.5 0.0 1.4 1 0 0 1 1 1 1 Endomembrane protein 70 tRNA-synt_1c PF00749.21 CCU99824.1 - 2.7e-104 348.4 0.1 4.8e-104 347.6 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 CCU99824.1 - 2.3e-40 138.2 0.0 3.6e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 CCU99824.1 - 7e-30 104.2 0.0 5.6e-29 101.2 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 CCU99824.1 - 0.00083 20.2 0.1 0.00083 20.2 0.1 2.1 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Clc-like PF07062.12 CCU99824.1 - 1.8 8.0 8.5 2.1 7.7 2.4 2.5 2 0 0 2 2 2 0 Clc-like Sybindin PF04099.12 CCU99825.1 - 5.1e-07 29.7 0.0 8.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family MDD_C PF18376.1 CCU99826.1 - 5.6e-73 244.7 0.0 7.2e-73 244.3 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CCU99826.1 - 4.1e-05 23.7 2.1 0.00011 22.4 2.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Ribosomal_L27e PF01777.18 CCU99827.1 - 1.2e-36 124.9 1.5 1.8e-36 124.4 1.5 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CCU99827.1 - 0.35 10.9 2.8 0.32 11.0 1.1 1.9 2 0 0 2 2 2 0 KOW motif Ribosom_S12_S23 PF00164.25 CCU99828.1 - 1.8e-48 162.8 0.9 2.5e-48 162.4 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 CBP4 PF07960.11 CCU99829.1 - 2.5e-11 43.5 0.1 4.8e-11 42.6 0.1 1.5 1 1 0 1 1 1 1 CBP4 MitoNEET_N PF10660.9 CCU99829.1 - 0.12 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Brix PF04427.18 CCU99830.1 - 1.2e-38 133.2 0.0 1.5e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Brix domain Erg28 PF03694.13 CCU99831.1 - 7.6e-35 119.6 0.3 8.8e-35 119.4 0.3 1.0 1 0 0 1 1 1 1 Erg28 like protein DUF4267 PF14087.6 CCU99831.1 - 0.047 13.8 0.8 0.069 13.2 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) GST_N_2 PF13409.6 CCU99832.1 - 1.3e-15 57.4 0.0 3e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCU99832.1 - 3.5e-15 55.8 0.0 8.3e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CCU99832.1 - 2.3e-06 27.7 0.0 4.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCU99832.1 - 0.00025 21.2 0.0 0.00053 20.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CCU99832.1 - 0.00028 20.6 0.0 0.00058 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCU99832.1 - 0.0004 20.7 0.0 0.53 10.7 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain POT1PC PF16686.5 CCU99833.1 - 3.1e-08 33.7 0.0 6.7e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 CCU99833.1 - 0.00034 20.5 0.0 0.00075 19.4 0.0 1.5 1 1 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 DUF1272 PF06906.11 CCU99833.1 - 0.063 13.4 0.9 0.18 11.9 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) tRNA-synt_2 PF00152.20 CCU99834.1 - 9.6e-76 254.8 0.0 1.2e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCU99834.1 - 1.7e-11 44.0 0.0 3.6e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCU99834.1 - 5.5e-08 32.6 0.0 8.9e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) IHABP4_N PF16174.5 CCU99834.1 - 0.052 14.1 1.8 0.1 13.2 1.8 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal zf-CCCH PF00642.24 CCU99836.1 - 1.9e-09 37.2 2.7 4.3e-09 36.0 2.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 CCU99836.1 - 1.1e-07 31.6 4.6 1.9e-07 30.8 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCU99836.1 - 1e-05 25.4 8.8 1.9e-05 24.6 8.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CCU99836.1 - 1.2e-05 25.2 8.9 2e-05 24.5 8.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 CCU99836.1 - 1.3e-05 25.0 4.4 2.7e-05 24.1 4.4 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_2 PF13923.6 CCU99836.1 - 7e-05 22.6 9.5 0.00013 21.7 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCU99836.1 - 0.00018 21.8 7.6 0.00035 20.9 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CCU99836.1 - 0.00041 20.4 7.4 0.00089 19.4 7.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CCU99836.1 - 0.00075 19.3 9.2 0.0013 18.5 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CCU99836.1 - 0.0012 18.9 3.0 0.0012 18.9 3.0 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 CCU99836.1 - 0.0027 17.5 2.9 0.0027 17.5 2.9 2.1 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 CCU99836.1 - 0.012 15.5 5.7 0.022 14.6 5.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CCU99836.1 - 0.015 15.1 2.1 0.025 14.4 2.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RanBP PF00641.18 CCU99836.1 - 0.13 11.6 0.2 0.29 10.5 0.2 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others GATase_5 PF13507.6 CCU99837.1 - 1.7e-91 306.0 0.0 2.9e-91 305.2 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CCU99837.1 - 1.6e-44 151.8 1.3 3.7e-30 105.1 0.0 2.8 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 CCU99837.1 - 2.2e-27 95.3 0.0 4.1e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 CCU99837.1 - 1.6e-21 76.6 0.0 3.3e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain ZZ PF00569.17 CCU99838.1 - 7.3e-09 35.3 4.8 1.3e-08 34.5 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CCU99838.1 - 1.2e-07 31.8 0.0 3.7e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCU99838.1 - 0.00044 20.5 0.0 0.0013 19.0 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 CCU99838.1 - 0.00097 19.4 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain zf-CCCH PF00642.24 CCU99839.1 - 2e-13 49.9 13.8 8.6e-07 28.7 4.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CCU99839.1 - 0.00016 21.9 5.9 0.0017 18.6 0.8 2.2 2 0 0 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 CCU99839.1 - 0.00023 21.1 9.6 0.015 15.3 2.9 2.7 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 CCU99839.1 - 0.00029 20.6 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 CCU99839.1 - 0.0039 17.9 2.1 0.14 12.9 0.1 2.4 2 0 0 2 2 2 1 Torus domain Ras PF00071.22 CCU99840.1 - 3.6e-43 147.0 0.0 4.5e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCU99840.1 - 1.5e-29 102.6 0.0 1.9e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU99840.1 - 2.8e-11 43.2 0.0 3e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCU99840.1 - 2.6e-07 30.7 0.0 3.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCU99840.1 - 0.00055 19.5 0.0 0.022 14.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CCU99840.1 - 0.015 15.4 0.1 0.027 14.5 0.1 1.5 1 1 0 1 1 1 0 Dynamin family SRPRB PF09439.10 CCU99840.1 - 0.029 13.8 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CCU99840.1 - 0.18 11.2 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MFS_1 PF07690.16 CCU99841.1 - 1.9e-34 119.1 45.4 1.3e-28 100.0 27.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCU99841.1 - 3.6e-29 101.9 20.6 1.3e-18 67.2 7.6 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 CCU99841.1 - 0.00057 19.3 10.7 0.013 14.8 1.7 2.6 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB DHHC PF01529.20 CCU99842.1 - 1.2e-30 106.4 2.3 1.2e-30 106.4 2.3 2.7 3 0 0 3 3 3 1 DHHC palmitoyltransferase TackOD1 PF18551.1 CCU99842.1 - 0.046 13.4 1.7 0.12 12.0 0.4 2.0 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zf-SNAP50_C PF12251.8 CCU99843.1 - 3.5e-12 46.4 0.0 3.8e-11 43.1 0.0 2.5 2 1 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal PI3_PI4_kinase PF00454.27 CCU99844.1 - 3.6e-15 56.5 0.0 1.7e-14 54.3 0.0 2.1 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase ATP11 PF06644.11 CCU99845.1 - 2.6e-79 266.9 5.0 3.1e-79 266.6 5.0 1.0 1 0 0 1 1 1 1 ATP11 protein OmpH PF03938.14 CCU99845.1 - 0.015 15.7 10.2 0.034 14.5 10.2 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GrpE PF01025.19 CCU99845.1 - 0.73 9.5 9.5 40 3.8 9.5 2.2 1 1 0 1 1 1 0 GrpE OSCP PF00213.18 CCU99848.1 - 5e-34 117.9 0.8 5.9e-34 117.7 0.8 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit eIF-3c_N PF05470.12 CCU99849.1 - 1.8e-167 558.3 6.9 1.8e-167 558.3 6.9 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CCU99849.1 - 3e-12 47.0 0.1 3.1e-11 43.7 0.0 2.8 2 1 0 2 2 2 1 PCI domain Sigma70_r4 PF04545.16 CCU99849.1 - 0.11 12.0 0.0 0.55 9.8 0.0 2.2 1 0 0 1 1 1 0 Sigma-70, region 4 Nop14 PF04147.12 CCU99849.1 - 0.12 10.6 18.6 0.21 9.8 18.6 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CCU99849.1 - 1.2 7.3 15.5 2.8 6.1 15.5 1.6 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpb4 PF03874.16 CCU99849.1 - 1.7 9.0 6.7 0.39 11.1 1.2 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb4 NOA36 PF06524.12 CCU99849.1 - 2.7 7.2 15.4 4.6 6.5 15.4 1.3 1 0 0 1 1 1 0 NOA36 protein Dfp1_Him1_M PF08630.10 CCU99850.1 - 3.7e-33 114.4 0.0 1e-32 113.0 0.0 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 CCU99850.1 - 1.8e-18 66.3 1.5 3.2e-18 65.6 1.5 1.4 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 CCU99850.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain DUF4769 PF15992.5 CCU99850.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) BRCT PF00533.26 CCU99850.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CCU99850.1 - 0.17 12.3 0.0 0.39 11.2 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain RNase_H PF00075.24 CCU99851.1 - 1.3e-33 116.2 0.0 1.7e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 CCU99851.1 - 5.7e-20 71.3 0.3 1.1e-19 70.4 0.3 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF218 PF02698.17 CCU99852.1 - 1.5e-10 41.2 0.0 2.3e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain FAD_binding_1 PF00667.20 CCU99853.1 - 3.2e-54 183.8 0.0 5.3e-54 183.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CCU99853.1 - 1.9e-30 105.9 0.1 4.4e-30 104.8 0.1 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CCU99853.1 - 7.7e-19 68.4 0.0 1.9e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Rad10 PF03834.14 CCU99854.1 - 3.2e-47 159.3 0.1 4.7e-47 158.7 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 CCU99854.1 - 6.2e-06 26.7 0.0 1.2e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain UIM PF02809.20 CCU99854.1 - 0.03 14.2 1.6 0.03 14.2 1.6 1.9 2 0 0 2 2 2 0 Ubiquitin interaction motif Ribosomal_S8e PF01201.22 CCU99855.1 - 1.9e-47 160.9 0.1 3e-47 160.2 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e Macoilin PF09726.9 CCU99855.1 - 6.9 5.1 10.5 9.1 4.7 10.5 1.1 1 0 0 1 1 1 0 Macoilin family Yip1 PF04893.17 CCU99856.1 - 5e-09 36.1 7.7 7e-09 35.6 7.7 1.3 1 0 0 1 1 1 1 Yip1 domain TssN PF17555.2 CCU99856.1 - 5.6 6.3 10.9 7.5 5.8 10.9 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Mlh1_C PF16413.5 CCU99857.1 - 1.2e-62 211.8 0.0 3.1e-62 210.4 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CCU99857.1 - 1.3e-32 112.0 0.0 2.1e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CCU99857.1 - 2.4e-12 46.8 0.0 8.4e-12 45.1 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CCU99857.1 - 1.1e-07 32.3 0.0 3.1e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RNase_PH PF01138.21 CCU99859.1 - 4e-14 53.3 0.0 8.9e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCU99859.1 - 6.1e-05 23.0 0.1 0.00016 21.6 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PTPA PF03095.15 CCU99861.1 - 7.3e-114 380.3 0.0 8.5e-114 380.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein WD40 PF00400.32 CCU99862.1 - 1.8e-10 41.2 1.5 0.0068 17.2 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat LisH PF08513.11 CCU99862.1 - 0.002 18.0 0.0 0.0049 16.8 0.0 1.7 1 0 0 1 1 1 1 LisH ANAPC4_WD40 PF12894.7 CCU99862.1 - 0.084 13.2 0.0 17 5.8 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RabGAP-TBC PF00566.18 CCU99863.1 - 6.8e-41 140.3 0.0 1.6e-40 139.1 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 CCU99864.1 - 3e-62 210.4 0.0 4.3e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99864.1 - 1.6e-35 122.7 0.0 3.7e-35 121.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU99864.1 - 0.0016 17.8 0.0 0.0039 16.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like DUF1674 PF07896.12 CCU99865.1 - 6.5e-20 71.4 1.2 6.5e-20 71.4 1.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) DUF4672 PF15716.5 CCU99866.1 - 0.73 9.4 15.5 0.12 12.0 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4672) P53_TAD PF08563.11 CCU99866.1 - 0.86 9.2 8.5 0.73 9.4 2.3 2.4 2 0 0 2 2 2 0 P53 transactivation motif CI-B14_5a PF07347.12 CCU99867.1 - 0.0017 18.2 0.6 0.0035 17.2 0.1 1.8 2 0 0 2 2 2 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Oxysterol_BP PF01237.18 CCU99868.1 - 4.6e-131 437.1 0.0 9e-131 436.1 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.6 CCU99868.1 - 1.8e-14 53.6 0.1 0.00014 22.0 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCU99868.1 - 2.3e-14 53.7 0.4 2.2e-07 31.4 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CCU99868.1 - 5.4e-12 44.8 0.3 0.0021 18.4 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.29 CCU99868.1 - 2.1e-10 41.1 0.1 5.7e-10 39.7 0.1 1.8 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 CCU99868.1 - 1.7e-09 38.0 0.0 2.9e-06 27.7 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CCU99868.1 - 2.1e-08 34.2 0.8 0.0011 19.3 0.1 3.7 3 0 0 3 3 3 1 Ankyrin repeat PH_8 PF15409.6 CCU99868.1 - 9.1e-05 22.7 1.0 0.00023 21.4 0.2 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 CCU99868.1 - 0.00061 20.2 0.3 0.003 18.0 0.3 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain ABA_GPCR PF12430.8 CCU99869.1 - 7.8e-34 117.0 5.4 2e-33 115.7 5.9 1.4 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CCU99869.1 - 1.6e-08 34.5 0.7 3.3e-08 33.5 0.1 1.9 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal FSH1 PF03959.13 CCU99871.1 - 2.9e-38 131.7 0.0 3.3e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) SAT PF16073.5 CCU99871.1 - 0.03 14.1 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis BAAT_C PF08840.11 CCU99871.1 - 0.038 13.9 0.0 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal UBA PF00627.31 CCU99872.1 - 4.8e-18 64.7 1.2 4.1e-10 39.4 0.0 2.9 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.11 CCU99872.1 - 3.7e-16 58.6 4.4 3.7e-16 58.6 4.4 2.3 3 0 0 3 3 3 1 XPC-binding domain TetR_C_28 PF17937.1 CCU99872.1 - 0.0055 17.1 0.2 0.0086 16.5 0.2 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain UBA_4 PF14555.6 CCU99872.1 - 0.0061 16.4 0.0 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 UBA-like domain AIB PF15334.6 CCU99872.1 - 0.065 12.6 0.3 0.091 12.1 0.3 1.1 1 0 0 1 1 1 0 Aurora kinase A and ninein interacting protein CSTF2_hinge PF14327.6 CCU99872.1 - 0.078 13.4 3.7 0.13 12.7 2.5 2.0 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 GatB_Yqey PF02637.18 CCU99872.1 - 0.19 11.6 0.0 0.9 9.4 0.0 1.9 2 0 0 2 2 2 0 GatB domain CAP_N PF01213.19 CCU99872.1 - 1.8 8.0 4.7 2.7 7.4 4.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CPSase_sm_chain PF00988.22 CCU99874.1 - 1.1e-44 151.4 0.0 1.6e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CCU99874.1 - 1e-36 126.5 0.0 1.3e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CCU99874.1 - 1.7e-05 24.7 0.0 6.8e-05 22.7 0.0 2.0 1 1 1 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 CCU99874.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family zf-met PF12874.7 CCU99875.1 - 4.2e-06 27.0 1.0 7.8e-06 26.1 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCU99875.1 - 0.00019 21.6 0.3 0.00039 20.6 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF4407 PF14362.6 CCU99875.1 - 0.036 13.4 2.3 0.043 13.2 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-U1 PF06220.12 CCU99875.1 - 0.095 12.5 0.3 0.2 11.5 0.3 1.5 1 0 0 1 1 1 0 U1 zinc finger DUF4192 PF13830.6 CCU99875.1 - 4.7 7.2 13.6 2.2 8.3 11.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) FUSC PF04632.12 CCU99875.1 - 4.9 5.6 7.2 6.9 5.1 7.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family tRNA-synt_1 PF00133.22 CCU99876.1 - 1.3e-230 766.8 0.0 1.7e-230 766.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CCU99876.1 - 7.8e-23 81.1 0.0 1.7e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CCU99876.1 - 5.4e-15 55.0 0.3 2.9e-05 23.0 0.1 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CCU99876.1 - 0.0015 18.0 0.0 0.0081 15.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain ATP-synt PF00231.19 CCU99877.1 - 7.8e-74 248.9 2.2 8.9e-74 248.7 2.2 1.0 1 0 0 1 1 1 1 ATP synthase RNA_Me_trans PF04252.13 CCU99877.1 - 0.028 14.0 0.1 1.4 8.4 0.0 2.7 2 1 1 3 3 3 0 Predicted SAM-dependent RNA methyltransferase eIF-5_eIF-2B PF01873.17 CCU99878.1 - 8.6e-42 141.7 0.2 1.4e-41 141.0 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 CCU99878.1 - 0.0019 17.7 0.1 0.0036 16.8 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 CCU99878.1 - 0.56 10.6 6.1 0.78 10.1 0.1 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain Mitofilin PF09731.9 CCU99878.1 - 1.4 7.7 8.8 1.6 7.4 8.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Tho1_MOS11_C PF18592.1 CCU99880.1 - 4.4e-15 55.2 5.0 9.3e-12 44.6 1.5 2.4 2 0 0 2 2 2 2 Tho1/MOS11 C-terminal domain SAP PF02037.27 CCU99880.1 - 2.2e-12 46.4 0.3 6.3e-12 45.0 0.3 1.8 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 CCU99880.1 - 0.055 13.2 0.2 0.055 13.2 0.2 2.2 2 1 0 2 2 2 0 HeH/LEM domain CCT_2 PF09425.10 CCU99880.1 - 0.15 12.0 0.2 0.15 12.0 0.2 3.5 3 0 0 3 3 3 0 Divergent CCT motif FANC_SAP PF18081.1 CCU99880.1 - 2.1 8.6 5.3 14 5.9 3.1 2.9 2 1 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain ADH_N PF08240.12 CCU99881.1 - 1.5e-27 95.7 0.8 3e-27 94.7 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCU99881.1 - 1.6e-23 83.1 0.3 3.3e-23 82.1 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCU99881.1 - 2.5e-08 35.0 0.1 4.3e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 CCU99881.1 - 1.5e-05 24.8 0.1 3.5e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 CCU99881.1 - 0.005 16.1 0.2 0.011 15.1 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 CCU99881.1 - 0.036 14.3 0.1 0.063 13.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain SPC25 PF06703.11 CCU99882.1 - 2e-08 34.2 0.0 0.00067 19.5 0.0 2.2 2 0 0 2 2 2 2 Microsomal signal peptidase 25 kDa subunit (SPC25) W2 PF02020.18 CCU99883.1 - 1.3e-16 60.5 0.0 4.7e-16 58.7 0.0 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon SNF2_N PF00176.23 CCU99884.1 - 2.7e-50 171.0 0.1 3.6e-50 170.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCU99884.1 - 2.6e-16 59.9 0.1 1e-14 54.8 0.0 2.9 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCU99884.1 - 2.7e-06 27.5 0.0 6.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CCU99884.1 - 0.00071 18.8 0.0 0.42 9.7 0.0 3.1 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 CCU99884.1 - 0.0013 18.0 0.5 0.0041 16.4 0.0 2.0 2 1 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase EBP PF05241.12 CCU99885.1 - 2.2e-30 105.4 5.1 2.6e-30 105.2 5.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2431 PF10354.9 CCU99888.1 - 1.8e-41 142.2 0.0 2.9e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) VirB3 PF05101.13 CCU99888.1 - 0.014 15.6 0.5 0.048 13.9 0.5 1.9 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DnaJ PF00226.31 CCU99889.1 - 2.5e-20 72.3 2.4 3.3e-20 72.0 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 CCU99889.1 - 1.2e-13 50.1 20.5 0.0016 18.4 0.2 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCU99889.1 - 2.3e-13 49.3 15.3 0.013 15.3 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 CCU99889.1 - 4.1e-12 46.1 19.8 3.6e-07 30.2 2.3 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCU99889.1 - 6.3e-10 39.4 29.1 0.0014 19.1 1.5 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 CCU99889.1 - 6.2e-09 35.9 25.9 0.92 10.5 1.0 8.2 6 2 3 9 9 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 CCU99889.1 - 9.5e-09 35.8 25.9 0.002 18.7 6.4 5.1 4 1 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCU99889.1 - 5.5e-08 32.7 9.1 0.007 16.7 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCU99889.1 - 3.8e-07 29.8 9.5 3.4 8.1 0.0 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CCU99889.1 - 1.6e-05 25.1 11.8 0.0093 16.2 0.0 4.6 4 2 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CCU99889.1 - 0.00038 20.1 13.0 0.021 14.5 0.3 4.9 5 1 1 6 6 5 2 TPR repeat TPR_20 PF14561.6 CCU99889.1 - 0.0011 19.2 16.5 0.11 12.8 0.2 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.17 CCU99889.1 - 0.002 18.6 10.3 0.16 12.4 0.7 3.7 2 1 0 3 3 3 2 Bacterial transcriptional activator domain TPR_7 PF13176.6 CCU99889.1 - 0.011 15.7 7.6 1.4 9.1 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCU99889.1 - 0.012 15.9 17.7 1.3 9.4 3.2 5.2 3 1 2 5 5 5 0 Tetratricopeptide repeat Acyl-CoA_dh_1 PF00441.24 CCU99889.1 - 0.11 12.6 1.9 0.26 11.5 1.9 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain TPR_6 PF13174.6 CCU99889.1 - 0.17 12.6 28.6 0.35 11.6 0.1 8.6 9 2 1 10 10 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 CCU99889.1 - 0.17 11.8 5.8 13 5.8 0.4 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat T2SSF PF00482.23 CCU99889.1 - 0.43 10.5 1.8 0.59 10.1 0.5 1.9 2 0 0 2 2 1 0 Type II secretion system (T2SS), protein F TPR_21 PF09976.9 CCU99889.1 - 2.6 7.7 19.6 1.3 8.6 10.2 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 CCU99889.1 - 5.7 7.9 11.9 40 5.2 0.7 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Bax1-I PF01027.20 CCU99890.1 - 8.6e-45 153.1 24.4 9.8e-45 152.9 24.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4044 PF13253.6 CCU99890.1 - 0.16 11.5 1.0 0.49 10.0 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) BaxI_1 PF12811.7 CCU99890.1 - 0.28 10.7 21.4 4.1 6.9 21.3 2.2 1 1 0 1 1 1 0 Bax inhibitor 1 like DUF2070 PF09843.9 CCU99890.1 - 0.36 9.1 13.8 0.46 8.7 13.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PIGA PF08288.12 CCU99891.1 - 5.6e-39 132.6 0.7 6.8e-38 129.2 0.1 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 CCU99891.1 - 1.4e-23 83.3 0.0 2.1e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCU99891.1 - 2.9e-22 79.6 0.1 6.4e-22 78.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCU99891.1 - 2.6e-20 73.1 0.8 2.6e-20 73.1 0.8 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 CCU99891.1 - 0.02 15.3 0.1 0.046 14.1 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 CCU99891.1 - 0.065 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like DUF2428 PF10350.9 CCU99892.1 - 1.6e-47 162.0 1.3 3.4e-47 161.0 1.3 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) Cnd1 PF12717.7 CCU99892.1 - 0.018 15.1 0.2 0.72 9.9 0.0 3.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CCU99892.1 - 0.021 15.0 23.8 0.1 12.9 0.5 7.4 7 0 0 7 7 7 0 HEAT repeat Complex1_30kDa PF00329.19 CCU99892.1 - 0.096 13.3 0.0 0.32 11.6 0.0 1.9 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Adaptin_N PF01602.20 CCU99892.1 - 0.34 9.4 1.0 0.82 8.1 0.1 2.0 3 0 0 3 3 3 0 Adaptin N terminal region AzlD PF05437.12 CCU99892.1 - 4.4 7.5 10.4 0.22 11.7 1.1 3.5 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) DNA_pol_E_B PF04042.16 CCU99893.1 - 4.7e-44 150.3 0.0 6.5e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 CCU99893.1 - 0.0055 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal Septin PF00735.18 CCU99895.1 - 1.7e-106 355.6 0.5 2.4e-106 355.1 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CCU99895.1 - 3.1e-09 36.9 0.2 1.9e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCU99895.1 - 1.3e-05 24.9 0.1 0.00023 20.8 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCU99895.1 - 3.9e-05 23.6 0.5 0.00036 20.5 0.3 2.4 2 1 0 2 2 2 1 RsgA GTPase Ras PF00071.22 CCU99895.1 - 0.00012 21.8 0.3 0.00048 19.8 0.0 2.1 2 0 0 2 2 2 1 Ras family Dynamin_N PF00350.23 CCU99895.1 - 0.00012 22.2 2.7 0.035 14.1 0.0 3.2 3 0 0 3 3 3 1 Dynamin family AIG1 PF04548.16 CCU99895.1 - 0.0005 19.5 0.5 0.0011 18.3 0.0 1.9 2 0 0 2 2 2 1 AIG1 family AAA_23 PF13476.6 CCU99895.1 - 0.0029 18.1 3.4 2.1 8.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CCU99895.1 - 0.0039 17.5 1.5 0.0069 16.7 0.0 2.3 2 2 1 3 3 3 1 AAA domain Roc PF08477.13 CCU99895.1 - 0.005 17.0 0.0 0.014 15.6 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CCU99895.1 - 0.007 16.8 1.3 0.019 15.3 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain Strep_SA_rep PF06696.11 CCU99895.1 - 0.011 15.7 0.4 0.011 15.7 0.4 2.5 1 1 1 2 2 2 0 Streptococcal surface antigen repeat NiFe-hyd_HybE PF11939.8 CCU99895.1 - 0.019 14.9 1.9 0.032 14.1 1.9 1.3 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE ABC_tran PF00005.27 CCU99895.1 - 0.02 15.4 0.3 0.02 15.4 0.3 2.4 2 2 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 CCU99895.1 - 0.034 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 CCU99895.1 - 0.094 12.5 0.1 9.6 5.9 0.0 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_P4 PF11602.8 CCU99895.1 - 0.096 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 FtsK_SpoIIIE PF01580.18 CCU99895.1 - 0.13 11.6 2.7 1.2 8.4 0.1 2.5 2 1 0 2 2 2 0 FtsK/SpoIIIE family IIGP PF05049.13 CCU99895.1 - 0.22 10.5 1.6 0.26 10.3 0.0 1.9 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) Exonuc_VII_L PF02601.15 CCU99895.1 - 0.27 10.8 6.8 0.43 10.1 6.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.17 CCU99895.1 - 2.6 8.1 9.4 1.5 8.9 0.0 2.7 2 1 0 2 2 2 0 Helicase HerA, central domain LRR_9 PF14580.6 CCU99896.1 - 7.2e-54 181.9 1.2 9.7e-54 181.5 1.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CCU99896.1 - 5.8e-10 39.3 15.1 2.4e-06 27.8 2.6 3.6 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCU99896.1 - 2e-08 33.9 17.2 4.1e-06 26.5 5.6 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CCU99896.1 - 0.0088 16.0 5.5 29 5.0 0.0 5.0 5 0 0 5 5 5 1 Leucine Rich repeat HTH_38 PF13936.6 CCU99896.1 - 0.055 13.2 1.1 0.7 9.7 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain LRR_1 PF00560.33 CCU99896.1 - 3.5 8.6 8.0 1.3e+02 3.8 0.5 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat AAA_9 PF12781.7 CCU99897.1 - 7.2e-62 208.4 0.5 4.9e-59 199.1 0.0 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 CCU99897.1 - 1.1e-38 133.2 2.2 2e-38 132.3 2.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CCU99897.1 - 2.5e-25 89.2 0.0 4.5e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 CCU99897.1 - 4.4e-20 72.1 0.9 8.3e-20 71.2 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 CCU99897.1 - 3.4e-19 69.1 0.0 1.2e-18 67.3 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain APG6_N PF17675.1 CCU99897.1 - 0.0076 16.8 0.9 0.0076 16.8 0.9 3.9 4 0 0 4 4 3 1 Apg6 coiled-coil region AAA_8 PF12780.7 CCU99897.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Taxilin PF09728.9 CCU99897.1 - 0.07 12.3 21.2 0.0038 16.4 14.6 2.1 2 1 0 2 2 2 0 Myosin-like coiled-coil protein AATF-Che1 PF13339.6 CCU99897.1 - 0.47 11.1 10.6 0.89 10.2 4.9 3.1 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor DUF948 PF06103.11 CCU99897.1 - 1.7 9.0 6.3 6.5 7.1 0.2 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) EMP24_GP25L PF01105.24 CCU99897.1 - 4.4 7.2 6.4 3.3 7.6 0.7 2.7 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD Spc7 PF08317.11 CCU99897.1 - 4.4 6.1 28.1 2.2 7.1 0.4 3.3 3 0 0 3 3 3 0 Spc7 kinetochore protein Caps_synth_GfcC PF06251.11 CCU99897.1 - 9.4 5.8 12.8 12 5.4 0.1 2.5 2 0 0 2 2 2 0 Capsule biosynthesis GfcC Jnk-SapK_ap_N PF09744.9 CCU99897.1 - 10 6.4 29.9 0.081 13.1 0.8 3.7 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 CBFB_NFYA PF02045.15 CCU99898.1 - 4.3e-23 81.7 10.9 2.5e-22 79.2 10.9 2.3 1 1 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B RR_TM4-6 PF06459.12 CCU99898.1 - 4.7 6.9 5.4 6.7 6.4 5.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 VPS13_mid_rpt PF16910.5 CCU99899.1 - 8e-89 297.1 6.0 1.4e-85 286.5 0.0 5.1 4 1 1 5 5 5 1 Repeating coiled region of VPS13 VPS13 PF16908.5 CCU99899.1 - 6.8e-77 258.4 0.4 4.3e-74 249.3 0.1 3.0 2 0 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 CCU99899.1 - 1.7e-69 233.2 5.0 2e-64 216.6 0.9 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 CCU99899.1 - 8.2e-62 209.0 0.0 3.2e-60 203.8 0.0 2.6 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 CCU99899.1 - 3.5e-38 130.3 0.1 1.5e-37 128.3 0.1 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 CCU99899.1 - 6.1e-07 29.7 0.0 3.2e-06 27.4 0.0 2.3 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain MRP-L47 PF06984.13 CCU99900.1 - 1.7e-18 66.5 1.2 2.6e-18 65.9 1.2 1.4 1 1 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 CCU99900.1 - 0.0018 18.2 1.0 0.013 15.4 0.4 2.3 2 0 0 2 2 2 1 Ribosomal L29 protein Nramp PF01566.18 CCU99901.1 - 5.7e-88 295.3 18.5 1.8e-50 172.0 1.8 2.1 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein TolA_bind_tri PF16331.5 CCU99901.1 - 0.0008 19.4 0.4 0.0017 18.4 0.4 1.4 1 0 0 1 1 1 1 TolA binding protein trimerisation ketoacyl-synt PF00109.26 CCU99902.1 - 8.8e-64 215.5 0.0 2e-63 214.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 CCU99902.1 - 2.4e-44 151.5 0.0 4.4e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 CCU99902.1 - 1e-40 140.3 0.0 2.3e-40 139.0 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 CCU99902.1 - 2.2e-35 122.2 0.0 1.6e-34 119.4 0.0 2.3 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 CCU99902.1 - 5.8e-33 113.4 0.1 8.8e-32 109.6 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 CCU99902.1 - 1.1e-24 87.2 0.0 1.9e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 CCU99902.1 - 9.5e-15 55.0 0.0 2.8e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 CCU99902.1 - 2.4e-13 50.1 0.0 1.6e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 CCU99902.1 - 3.6e-11 43.2 0.1 3.6e-10 39.9 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCU99902.1 - 4.7e-07 30.9 0.1 3e-06 28.3 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 CCU99902.1 - 0.00019 21.7 0.6 0.00051 20.3 0.6 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 CCU99902.1 - 0.00066 19.2 0.0 0.024 14.1 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 CCU99902.1 - 0.0015 18.4 0.3 0.015 15.1 0.0 2.6 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Methyltransf_12 PF08242.12 CCU99902.1 - 0.0025 18.5 0.0 0.0072 17.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCU99902.1 - 0.0048 16.7 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NmrA PF05368.13 CCU99902.1 - 0.0092 15.6 0.1 0.023 14.3 0.1 1.7 1 0 0 1 1 1 1 NmrA-like family ThiF PF00899.21 CCU99902.1 - 0.098 12.0 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 ThiF family YAcAr PF10686.9 CCU99902.1 - 0.1 12.5 0.4 15 5.6 0.1 3.2 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family Methyltransf_11 PF08241.12 CCU99902.1 - 0.12 13.0 0.0 0.4 11.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Nup96 PF12110.8 CCU99903.1 - 2.6e-89 299.2 10.4 2.6e-89 299.2 10.4 1.6 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.14 CCU99903.1 - 2.5e-51 173.7 0.0 3.7e-51 173.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 CCU99903.1 - 7.2e-21 74.8 289.3 4.3e-05 24.3 29.3 9.6 3 2 5 8 8 8 6 Nucleoporin FG repeat region DUF2600 PF10776.9 CCU99903.1 - 0.066 12.1 0.6 0.11 11.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) HSCB_C PF07743.13 CCU99904.1 - 1.1e-17 64.2 5.9 1.5e-17 63.8 5.3 1.5 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CCU99904.1 - 9.3e-07 28.9 0.0 2.5e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.7 CCU99904.1 - 0.023 14.7 0.8 0.037 14.0 0.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-tcix PF14952.6 CCU99904.1 - 0.028 14.1 3.8 0.046 13.3 3.8 1.3 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Foie-gras_1 PF11817.8 CCU99904.1 - 0.029 13.9 0.2 0.059 13.0 0.2 1.6 1 1 0 1 1 1 0 Foie gras liver health family 1 DUF4570 PF15134.6 CCU99904.1 - 0.077 13.0 1.3 0.13 12.3 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) SpoIIE PF07228.12 CCU99905.1 - 6e-12 45.9 0.0 6.5e-11 42.5 0.0 2.3 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CCU99905.1 - 4.5e-05 23.2 0.0 0.00021 21.0 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CCU99905.1 - 0.035 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C DUF4110 PF13422.6 CCU99906.1 - 1.3e-10 41.2 1.2 3e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 CCU99906.1 - 1.5e-07 31.5 0.2 0.00048 20.3 0.0 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.6 CCU99906.1 - 1.2e-06 28.4 5.5 0.018 15.1 0.2 3.7 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CCU99906.1 - 2.7e-06 27.5 0.2 0.0011 19.1 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 CCU99906.1 - 0.0047 16.5 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CCU99906.1 - 0.0061 16.5 0.0 0.37 10.9 0.1 2.9 3 1 0 3 3 3 1 Kelch motif S-antigen PF05756.11 CCU99906.1 - 0.061 13.7 6.5 0.2 12.1 0.7 2.6 1 1 1 2 2 2 0 S-antigen protein Kelch_5 PF13854.6 CCU99906.1 - 0.078 13.0 1.3 6.2 6.9 0.1 3.4 3 0 0 3 3 3 0 Kelch motif DUF4708 PF15813.5 CCU99906.1 - 0.15 11.2 0.1 0.28 10.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) GCIP PF13324.6 CCU99906.1 - 0.48 10.0 4.7 0.85 9.2 4.7 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CDC45 PF02724.14 CCU99906.1 - 0.83 7.9 3.8 1.1 7.5 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Dicty_REP PF05086.12 CCU99906.1 - 1 7.2 3.3 1.4 6.8 3.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RXT2_N PF08595.11 CCU99906.1 - 6.6 6.7 7.3 3 7.8 3.8 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal COPIIcoated_ERV PF07970.12 CCU99907.1 - 7e-29 101.3 0.1 1.2e-27 97.2 0.0 2.5 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CCU99907.1 - 3.2e-14 53.0 0.1 5.5e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) LSM PF01423.22 CCU99908.1 - 6.6e-17 61.0 0.2 1.5e-15 56.6 0.2 2.2 1 1 0 1 1 1 1 LSM domain Tospo_nucleocap PF01533.16 CCU99908.1 - 0.15 11.5 0.0 0.19 11.2 0.0 1.2 1 1 0 1 1 1 0 Tospovirus nucleocapsid protein FoP_duplication PF13865.6 CCU99908.1 - 0.96 10.0 6.0 1.8 9.1 6.0 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 WD40 PF00400.32 CCU99909.1 - 2.2e-10 41.0 3.4 0.46 11.5 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Ctr PF04145.15 CCU99910.1 - 2.1e-18 67.3 0.0 3.2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Ctr copper transporter family WD40 PF00400.32 CCU99911.1 - 4.1e-32 109.7 31.1 1.9e-07 31.7 0.2 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCU99911.1 - 3.1e-10 40.2 1.8 0.034 14.4 0.0 6.4 2 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 CCU99911.1 - 4.6e-08 32.8 1.2 1.3e-07 31.4 1.2 1.8 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 CCU99911.1 - 1.3e-07 30.7 2.4 0.077 11.6 0.1 4.7 2 2 3 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 CCU99911.1 - 1.6e-06 27.7 0.0 0.0038 16.6 0.0 3.2 3 0 0 3 3 3 2 WD40-like domain F-box PF00646.33 CCU99911.1 - 1.6e-05 24.6 0.1 3.6e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain DUF5046 PF16465.5 CCU99911.1 - 0.032 13.7 0.1 0.55 9.6 0.0 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF5046) PQQ_3 PF13570.6 CCU99911.1 - 0.15 12.5 8.4 6.2 7.4 0.1 5.5 7 0 0 7 7 7 0 PQQ-like domain TPR_1 PF00515.28 CCU99912.1 - 1.8e-23 81.4 9.7 6.2e-05 22.6 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 CCU99912.1 - 3e-22 76.9 19.7 0.00062 19.7 0.1 7.8 8 0 0 8 8 7 5 Tetratricopeptide repeat DnaJ PF00226.31 CCU99912.1 - 6.2e-22 77.5 0.3 2.4e-21 75.6 0.1 2.2 2 0 0 2 2 1 1 DnaJ domain TPR_16 PF13432.6 CCU99912.1 - 9.3e-17 61.4 29.6 0.00027 21.5 1.7 6.5 4 3 1 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.6 CCU99912.1 - 3.2e-14 53.2 24.6 2.7e-08 34.2 1.9 5.8 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CCU99912.1 - 7.7e-11 41.9 26.0 0.068 14.0 0.3 7.6 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CCU99912.1 - 2e-08 33.8 11.2 0.3 11.4 0.0 7.1 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCU99912.1 - 2.3e-08 33.6 14.4 0.0023 17.6 0.0 6.3 6 1 1 7 7 7 3 TPR repeat TPR_12 PF13424.6 CCU99912.1 - 1.9e-07 31.3 21.2 0.0049 17.1 0.5 6.8 5 2 2 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CCU99912.1 - 4.3e-07 30.1 2.7 0.022 15.0 0.2 4.3 3 2 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CCU99912.1 - 3.7e-06 26.6 14.8 0.87 9.8 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCU99912.1 - 0.00011 22.4 9.0 4.7 7.8 0.3 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 CCU99912.1 - 0.00029 20.2 9.1 0.1 12.1 0.1 5.2 5 0 0 5 5 5 1 SHNi-TPR TPR_9 PF13371.6 CCU99912.1 - 0.0033 17.5 27.7 0.0092 16.1 0.3 6.1 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 CCU99912.1 - 0.024 14.5 20.1 1.8 8.5 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF3856 PF12968.7 CCU99912.1 - 0.05 13.7 10.4 0.92 9.6 0.8 4.1 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 CCU99912.1 - 1.3 9.8 21.5 9.6 7.1 0.1 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CCU99912.1 - 3.2 8.2 9.7 1.4 9.4 0.3 3.5 3 1 1 4 4 4 0 Alkyl sulfatase dimerisation PseudoU_synth_1 PF01416.20 CCU99913.1 - 1e-11 45.3 0.0 4.3e-09 36.8 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase Plus-3 PF03126.18 CCU99914.1 - 2.5e-22 79.4 0.0 8.4e-22 77.8 0.0 1.9 1 0 0 1 1 1 1 Plus-3 domain Transketolase_C PF02780.20 CCU99914.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain Actin PF00022.19 CCU99915.1 - 1e-89 301.0 0.0 9e-89 297.9 0.0 2.2 1 1 0 1 1 1 1 Actin Pirin PF02678.16 CCU99916.1 - 5.9e-27 93.8 0.4 2.5e-26 91.7 0.3 2.0 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 CCU99916.1 - 5.7e-25 87.7 0.0 1.8e-24 86.1 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 CCU99916.1 - 0.0012 18.5 2.8 0.0047 16.6 1.5 2.5 3 0 0 3 3 3 1 Cupin domain ABC1 PF03109.16 CCU99917.1 - 1.7e-29 102.4 0.0 2.8e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Oxidored-like PF09791.9 CCU99917.1 - 4.1e-18 64.8 0.7 1e-17 63.5 0.7 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Na_trans_assoc PF06512.13 CCU99917.1 - 0.0034 17.7 0.1 0.0055 17.0 0.1 1.3 1 0 0 1 1 1 1 Sodium ion transport-associated COX5A PF02284.16 CCU99918.1 - 4e-42 142.4 0.1 4.7e-42 142.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va SNF2_N PF00176.23 CCU99919.1 - 9.1e-47 159.5 0.0 1.4e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCU99919.1 - 4.1e-07 30.3 0.0 1.8e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 CCU99919.1 - 2.3e-06 27.4 11.7 4.2e-06 26.5 11.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCU99919.1 - 3.6e-06 26.7 11.7 6.4e-06 25.9 11.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CCU99919.1 - 6.4e-06 25.9 14.4 1.2e-05 25.0 14.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCU99919.1 - 6.9e-05 23.1 15.2 0.00013 22.2 15.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CCU99919.1 - 0.00035 20.4 13.3 0.00063 19.6 13.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCU99919.1 - 0.00053 19.9 15.1 0.00091 19.1 15.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-UDP PF14569.6 CCU99919.1 - 0.0018 18.3 3.3 0.0045 17.1 3.3 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 CCU99919.1 - 0.16 11.7 9.0 0.31 10.9 9.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 CCU99919.1 - 0.17 11.8 4.7 0.27 11.2 3.6 1.8 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 CCU99919.1 - 0.86 9.5 6.3 2 8.3 6.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 CCU99919.1 - 1.3 8.7 12.4 2.7 7.7 12.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 CCU99919.1 - 4.1 7.6 10.5 7.2 6.9 10.5 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Myb_DNA-bind_6 PF13921.6 CCU99921.1 - 3e-09 37.0 0.0 5.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CCU99921.1 - 1.2e-07 31.8 0.0 2.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain RRM_1 PF00076.22 CCU99922.1 - 2.9e-12 46.2 0.0 3.5e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCU99922.1 - 0.034 13.8 0.0 0.96 9.0 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 CCU99923.1 - 6e-60 201.5 0.0 7.5e-60 201.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCU99923.1 - 8.4e-38 129.3 0.1 1.1e-37 128.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU99923.1 - 5.6e-14 52.0 0.0 6.8e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCU99923.1 - 3.5e-06 26.5 0.0 4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCU99923.1 - 5.3e-06 26.5 0.0 6.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCU99923.1 - 8.7e-06 25.4 0.0 1.4e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCU99923.1 - 4.6e-05 23.4 0.5 0.026 14.4 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CCU99923.1 - 0.043 14.2 0.1 0.096 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 CCU99923.1 - 0.084 12.4 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain TniB PF05621.11 CCU99923.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Pantoate_ligase PF02569.15 CCU99924.1 - 1.8e-85 286.4 0.0 2.1e-85 286.2 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Peptidase_M24 PF00557.24 CCU99925.1 - 3e-37 128.4 0.0 4.6e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 EF1G PF00647.19 CCU99927.1 - 1.7e-46 156.6 0.1 3e-46 155.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 CCU99927.1 - 2.4e-13 50.2 0.1 8.1e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CCU99927.1 - 5.3e-11 42.8 0.0 1.1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CCU99927.1 - 2.9e-09 37.0 0.0 6.6e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCU99927.1 - 8.4e-08 32.3 0.2 3.5e-07 30.3 0.0 2.2 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCU99927.1 - 9.1e-07 28.8 0.1 1.8e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CCU99927.1 - 2.4e-05 24.5 0.0 5.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AbiH PF14253.6 CCU99927.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Proteasome PF00227.26 CCU99928.1 - 2.1e-59 200.2 0.3 2.8e-59 199.8 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCU99928.1 - 2.4e-14 52.7 0.2 5.4e-14 51.5 0.2 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature LSM PF01423.22 CCU99929.1 - 6.9e-14 51.3 0.1 8.6e-14 51.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 CCU99929.1 - 0.0047 17.0 0.0 0.0063 16.6 0.0 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 CCU99929.1 - 0.0063 16.6 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain HMG_box PF00505.19 CCU99930.1 - 4.3e-25 87.9 0.8 6.1e-25 87.4 0.8 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCU99930.1 - 1.2e-18 67.5 1.5 1.8e-18 66.9 1.5 1.3 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 CCU99930.1 - 0.0015 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.13 CCU99930.1 - 0.048 14.2 0.8 0.061 13.9 0.1 1.5 2 0 0 2 2 2 0 YABBY protein Mito_carr PF00153.27 CCU99931.1 - 6.9e-34 115.7 0.3 3.3e-23 81.4 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.27 CCU99932.1 - 3.1e-22 78.3 0.1 4e-18 65.1 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein FlaC_arch PF05377.11 CCU99933.1 - 0.3 11.5 1.1 14 6.2 0.7 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FlxA PF14282.6 CCU99933.1 - 0.82 9.7 4.6 8.6 6.4 1.9 2.9 1 1 1 2 2 2 0 FlxA-like protein CdvA PF18822.1 CCU99933.1 - 1.4 8.7 8.9 0.98 9.3 0.4 2.9 3 0 0 3 3 3 0 CdvA-like coiled-coil domain APG6_N PF17675.1 CCU99933.1 - 7.7 7.1 39.6 2.8 8.5 10.5 3.8 1 1 1 2 2 2 0 Apg6 coiled-coil region RRM_1 PF00076.22 CCU99934.1 - 5.3e-74 244.0 0.0 3.8e-18 65.1 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCU99934.1 - 8.6e-05 22.3 0.0 8.2 6.4 0.0 4.0 4 0 0 4 4 4 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 CCU99934.1 - 0.0002 21.6 0.8 9.6 6.4 0.0 6.1 5 3 3 8 8 8 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 CCU99934.1 - 0.00029 20.9 0.0 1.1 9.4 0.0 4.0 4 0 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 CCU99934.1 - 0.0044 17.1 0.2 0.29 11.3 0.0 3.9 5 0 0 5 5 5 1 Limkain b1 RRM_Rrp7 PF17799.1 CCU99934.1 - 0.039 13.8 0.0 5.5 6.8 0.0 3.6 4 0 0 4 4 4 0 Rrp7 RRM-like N-terminal domain Miff PF05644.11 CCU99934.1 - 0.039 13.6 0.1 0.039 13.6 0.1 2.2 3 0 0 3 3 3 0 Mitochondrial and peroxisomal fission factor Mff RNA_polI_A34 PF08208.11 CCU99934.1 - 0.18 11.9 13.2 0.65 10.1 1.9 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 PCI PF01399.27 CCU99935.1 - 6.1e-23 81.3 0.6 2.2e-22 79.6 0.2 2.2 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.11 CCU99935.1 - 3.6e-22 78.6 2.4 1.6e-21 76.4 2.4 2.2 1 1 0 1 1 1 1 Proteasome regulatory subunit C-terminal Med10 PF09748.9 CCU99935.1 - 2.4e-14 53.3 0.0 9.1e-14 51.5 0.0 2.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex CTP_transf_like PF01467.26 CCU99936.1 - 6.4e-26 91.3 0.0 7.9e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like RRM_1 PF00076.22 CCU99937.1 - 6.9e-14 51.4 0.0 9.1e-14 51.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CCU99937.1 - 0.00027 20.9 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Complex1_LYR PF05347.15 CCU99938.1 - 4.9e-08 32.9 0.7 1.6e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CCU99938.1 - 0.00027 21.6 0.0 0.00038 21.2 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Metallophos PF00149.28 CCU99939.1 - 1.9e-33 116.7 0.0 2.9e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pyr_redox_2 PF07992.14 CCU99940.1 - 2.6e-63 214.0 7.4 4.2e-63 213.3 7.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CCU99940.1 - 1.6e-41 141.0 0.1 4.2e-41 139.6 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CCU99940.1 - 1.1e-22 80.4 6.4 1.1e-19 70.7 1.1 3.4 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCU99940.1 - 5.6e-13 48.8 1.2 5.3e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCU99940.1 - 9.3e-12 45.0 9.3 8.5e-11 41.8 0.2 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCU99940.1 - 5.1e-09 36.2 4.4 9.5e-05 22.6 0.4 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CCU99940.1 - 8.9e-09 35.0 4.7 0.0054 16.0 0.1 3.4 3 1 0 3 3 3 3 FAD binding domain HI0933_like PF03486.14 CCU99940.1 - 4.1e-07 29.1 11.4 0.00012 20.9 0.7 4.1 4 0 0 4 4 4 3 HI0933-like protein AlaDh_PNT_C PF01262.21 CCU99940.1 - 4.8e-07 29.3 1.6 0.0033 16.7 0.3 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 CCU99940.1 - 1.8e-06 27.3 2.2 1.8e-06 27.3 2.2 3.3 3 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 CCU99940.1 - 1.4e-05 24.4 3.5 0.0027 17.0 0.1 2.6 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 CCU99940.1 - 0.00032 19.9 14.3 0.004 16.3 6.3 3.5 3 1 0 3 3 3 2 Glucose inhibited division protein A K_oxygenase PF13434.6 CCU99940.1 - 0.0011 18.2 1.0 0.33 10.0 0.1 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 CCU99940.1 - 0.0018 17.7 0.3 0.03 13.6 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 CCU99940.1 - 0.0069 16.0 11.8 1.4 8.4 0.1 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CCU99940.1 - 0.33 10.0 3.5 1.6 7.7 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 CCU99940.1 - 0.85 10.1 3.0 3.1 8.3 0.6 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding Mg_trans_NIPA PF05653.14 CCU99941.1 - 3.9e-62 210.0 6.3 5.4e-62 209.6 6.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CCU99941.1 - 0.0026 17.9 3.2 0.0026 17.9 3.2 3.2 3 1 1 4 4 4 1 EamA-like transporter family MT-A70 PF05063.14 CCU99942.1 - 3.6e-40 137.7 0.0 4.9e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Bap31 PF05529.12 CCU99943.1 - 5.1e-40 136.5 10.3 9.2e-40 135.6 10.3 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CCU99943.1 - 6.9e-10 38.8 5.0 1.1e-09 38.1 5.0 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain SecY PF00344.20 CCU99943.1 - 0.016 14.5 1.1 0.019 14.2 1.1 1.1 1 0 0 1 1 1 0 SecY translocase DUF1077 PF06417.12 CCU99943.1 - 0.53 10.3 4.2 0.57 10.2 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1077) DivIC PF04977.15 CCU99943.1 - 1.3 8.9 4.9 2.4 8.0 2.3 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF89 PF01937.19 CCU99944.1 - 2.6e-108 362.1 0.0 3e-108 361.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 NIF3 PF01784.18 CCU99945.1 - 2.2e-54 184.7 0.0 3e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RNA_pol_Rpb2_6 PF00562.28 CCU99946.1 - 3.4e-126 421.5 0.0 5.9e-126 420.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CCU99946.1 - 6.7e-58 195.6 0.0 9.5e-58 195.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CCU99946.1 - 4.1e-36 124.4 0.3 8.9e-36 123.3 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CCU99946.1 - 1.5e-31 108.6 0.2 3.7e-31 107.4 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CCU99946.1 - 3.7e-24 84.8 0.6 1e-23 83.4 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CCU99946.1 - 5e-20 71.5 0.0 1.3e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CCU99946.1 - 5.3e-10 39.7 0.0 1.4e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF3128 PF11326.8 CCU99947.1 - 1.1e-22 80.2 0.6 1.3e-22 79.9 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Prefoldin PF02996.17 CCU99948.1 - 6.5e-26 90.6 0.0 1.1e-25 89.9 0.0 1.4 1 1 0 1 1 1 1 Prefoldin subunit GTP_EFTU PF00009.27 CCU99949.1 - 2.8e-28 98.8 4.8 2.8e-28 98.8 4.8 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CCU99949.1 - 3.9e-22 78.4 0.0 1.3e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CCU99949.1 - 3.1e-08 33.7 0.6 9.6e-08 32.1 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CCU99949.1 - 3.4e-06 27.3 5.5 0.00018 21.9 1.1 3.2 3 0 0 3 3 3 2 Elongation factor Tu domain 2 FeoB_N PF02421.18 CCU99949.1 - 0.00011 21.7 0.1 0.00028 20.5 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CCU99949.1 - 0.00035 20.5 0.8 0.12 12.3 0.0 2.6 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CCU99949.1 - 0.0026 17.2 0.0 0.0054 16.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 CCU99949.1 - 0.0054 16.5 0.3 0.093 12.5 0.3 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 CCU99949.1 - 0.046 13.9 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 CCU99949.1 - 0.098 13.1 0.0 4.9 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain UQ_con PF00179.26 CCU99950.1 - 3.1e-45 153.2 0.0 3.6e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCU99950.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B CAF1 PF04857.20 CCU99951.1 - 7.4e-19 68.1 0.0 2.3e-09 36.9 0.1 2.4 2 1 0 2 2 2 2 CAF1 family ribonuclease VWA_2 PF13519.6 CCU99952.1 - 3.1e-16 60.0 0.1 1.4e-15 57.9 0.1 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.20 CCU99952.1 - 5.5e-06 25.9 27.7 0.0038 17.0 1.8 4.2 4 0 0 4 4 4 3 Ubiquitin interaction motif VWA PF00092.28 CCU99952.1 - 5.6e-05 23.5 0.1 0.0001 22.6 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Herpes_UL21 PF03252.13 CCU99952.1 - 0.012 14.5 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 Ssl1 PF04056.14 CCU99952.1 - 0.022 14.6 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Ssl1-like Dynein_heavy PF03028.15 CCU99952.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain RE_HindIII PF09518.10 CCU99952.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 HindIII restriction endonuclease RAP80_UIM PF18282.1 CCU99952.1 - 8.8 6.2 15.1 1.6 8.6 0.2 3.9 3 1 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif RNase_PH PF01138.21 CCU99955.1 - 1.9e-25 89.8 0.0 4e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCU99955.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Gp_dh_C PF02800.20 CCU99956.1 - 4.6e-69 231.0 0.0 6.5e-69 230.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CCU99956.1 - 7.7e-38 128.9 0.2 2e-37 127.6 0.1 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain RhoGEF PF00621.20 CCU99957.1 - 5.6e-37 127.7 1.3 8.4e-37 127.2 1.3 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 CCU99957.1 - 2.1e-31 108.7 0.0 3.6e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 CCU99957.1 - 9.3e-25 86.7 0.0 1.6e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 CCU99957.1 - 8.8e-05 22.4 0.2 0.00047 20.0 0.1 2.2 2 0 0 2 2 2 1 PB1 domain Abhydrolase_3 PF07859.13 CCU99957.1 - 0.03 14.2 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold PH PF00169.29 CCU99957.1 - 0.16 12.5 0.0 0.39 11.2 0.0 1.6 2 0 0 2 2 2 0 PH domain Thioredoxin PF00085.20 CCU99958.1 - 5.2e-56 187.0 0.3 8.3e-30 102.8 0.0 4.0 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CCU99958.1 - 5.3e-32 111.2 0.0 4.1e-23 82.2 0.0 3.4 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CCU99958.1 - 1.1e-07 32.1 0.1 0.47 10.8 0.0 4.6 4 1 0 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 CCU99958.1 - 1.2e-07 31.7 0.6 0.28 11.1 0.0 4.3 4 1 0 4 4 4 2 AhpC/TSA family Thioredoxin_7 PF13899.6 CCU99958.1 - 5.8e-07 29.6 0.1 0.071 13.3 0.0 3.6 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CCU99958.1 - 1.2e-06 29.0 0.1 0.59 10.6 0.1 4.3 3 1 1 4 4 4 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CCU99958.1 - 6.8e-06 25.6 0.0 0.01 15.2 0.0 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Redoxin PF08534.10 CCU99958.1 - 0.00035 20.3 0.9 2 8.1 0.0 3.5 3 0 0 3 3 3 2 Redoxin TraF PF13728.6 CCU99958.1 - 0.005 16.7 0.1 31 4.3 0.0 4.0 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CCU99958.1 - 0.04 13.7 0.1 7 6.4 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.6 CCU99958.1 - 0.052 13.7 0.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin ALO PF04030.14 CCU99959.1 - 4.7e-59 200.3 0.2 8.2e-59 199.5 0.1 1.4 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CCU99959.1 - 4.4e-20 71.8 0.0 9e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain PCI PF01399.27 CCU99960.1 - 9.9e-11 42.1 0.0 4.4e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 PCI domain DUF3562 PF12085.8 CCU99960.1 - 0.054 13.1 0.3 2.6 7.7 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3562) DUF4470 PF14737.6 CCU99960.1 - 0.096 12.9 0.2 8.5 6.6 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4470) PIG-L PF02585.17 CCU99961.1 - 1.2e-23 84.2 0.6 1.8e-23 83.6 0.6 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Pkinase PF00069.25 CCU99962.1 - 1.7e-42 145.6 0.0 2.1e-41 142.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99962.1 - 1.4e-26 93.4 0.0 1.8e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCU99962.1 - 2.3e-05 23.8 0.0 4.9e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CCU99962.1 - 0.00074 19.5 3.6 0.021 14.8 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Gemini_AL2 PF01440.16 CCU99962.1 - 0.0017 18.8 0.1 0.0059 17.0 0.1 1.8 1 0 0 1 1 1 1 Geminivirus AL2 protein Kdo PF06293.14 CCU99962.1 - 0.066 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CCU99962.1 - 0.24 11.0 0.0 0.91 9.1 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase VHS PF00790.19 CCU99963.1 - 0.00026 20.9 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 VHS domain DUF1431 PF07248.12 CCU99963.1 - 0.16 12.2 0.3 0.4 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1431) HIG_1_N PF04588.13 CCU99964.1 - 4.9e-09 36.3 3.8 7.6e-09 35.7 3.8 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region muHD PF10291.9 CCU99965.1 - 1.8e-26 93.1 0.0 3.4e-26 92.2 0.0 1.4 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 CCU99965.1 - 7.2e-07 29.4 0.1 7.2e-07 29.4 0.1 2.7 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Pannexin_like PF12534.8 CCU99965.1 - 0.0072 15.5 1.7 0.012 14.7 1.7 1.2 1 0 0 1 1 1 1 Pannexin-like TM region of LRRC8 FlgN PF05130.12 CCU99965.1 - 0.015 15.8 4.0 0.043 14.3 4.0 1.8 1 0 0 1 1 1 0 FlgN protein PP_kinase_N PF13089.6 CCU99965.1 - 0.62 10.4 2.2 0.56 10.6 0.1 2.0 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain Pkinase PF00069.25 CCU99966.1 - 3.5e-66 223.3 0.0 4.3e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCU99966.1 - 2.4e-32 112.2 0.0 3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCU99966.1 - 1.1e-05 24.5 0.0 1.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CCU99966.1 - 0.00059 19.3 0.0 0.0015 17.9 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCU99966.1 - 0.0015 18.5 0.0 0.0034 17.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CCU99966.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 CCU99966.1 - 0.026 14.1 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CCU99966.1 - 0.057 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Mid1 PF12929.7 CCU99967.1 - 3.3e-71 240.7 0.0 6.6e-71 239.7 0.0 1.4 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 CCU99967.1 - 0.0036 17.9 4.1 0.11 13.1 0.5 2.6 2 0 0 2 2 2 2 Fz domain FtsJ PF01728.19 CCU99967.1 - 0.15 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Rft-1 PF04506.13 CCU99968.1 - 1.9e-82 277.7 0.0 2.4e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 Rft protein Membr_traf_MHD PF10540.9 CCU99969.1 - 4.6e-15 56.1 0.0 1.2e-06 28.8 0.0 2.7 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 CCU99969.1 - 2e-05 23.3 0.1 4.5e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) C2 PF00168.30 CCU99969.1 - 0.00071 19.8 0.0 0.0023 18.2 0.0 1.8 2 0 0 2 2 2 1 C2 domain RRM_1 PF00076.22 CCU99970.1 - 4.8e-36 122.4 0.0 5.9e-17 61.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCU99970.1 - 1.4e-13 50.7 0.1 1.2e-05 25.4 0.0 2.7 2 2 0 2 2 2 2 RNA recognition motif Lipoprotein_18 PF06804.11 CCU99970.1 - 0.0019 17.4 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 NlpB/DapX lipoprotein PHM7_cyt PF14703.6 CCU99970.1 - 0.044 14.0 0.0 1.3 9.2 0.0 2.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DNA_pol_viral_N PF00242.17 CCU99970.1 - 0.059 12.8 1.5 0.087 12.3 1.5 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Nup35_RRM_2 PF14605.6 CCU99970.1 - 0.093 12.8 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PTR2 PF00854.21 CCU99971.1 - 5e-72 242.9 3.5 5e-72 242.9 3.5 1.5 1 1 1 2 2 2 1 POT family MFS_1 PF07690.16 CCU99971.1 - 0.00013 21.0 32.9 0.001 18.1 27.8 2.8 1 1 0 2 2 2 2 Major Facilitator Superfamily RNA_pol_L_2 PF13656.6 CCU99972.1 - 3.3e-29 100.4 0.0 4.3e-29 100.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CCU99972.1 - 1.1e-10 40.8 0.0 1.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sec1 PF00995.23 CCU99974.1 - 2.5e-120 403.4 0.0 2.8e-120 403.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Aa_trans PF01490.18 CCU99975.1 - 8.9e-16 57.6 43.8 2.2e-15 56.3 43.8 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein OGFr_III PF04680.13 CCU99975.1 - 0.24 12.0 0.0 0.24 12.0 0.0 2.4 2 0 0 2 2 2 0 Opioid growth factor receptor repeat Mito_carr PF00153.27 CCU99976.1 - 1.9e-44 149.5 0.2 1.5e-19 69.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PAE PF03283.13 CCU99976.1 - 0.066 12.3 0.0 0.13 11.4 0.0 1.4 2 0 0 2 2 2 0 Pectinacetylesterase Utp21 PF04192.12 CCU99980.1 - 1.6e-48 165.3 0.0 3.2e-48 164.3 0.0 1.5 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 CCU99980.1 - 4.6e-13 49.3 0.0 0.0063 16.8 0.0 6.5 3 2 6 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCU99980.1 - 2.8e-11 43.8 9.8 0.12 13.3 0.0 9.0 9 0 0 9 9 9 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CCU99980.1 - 0.0005 19.1 2.6 0.52 9.2 0.0 3.6 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ELYS-bb PF16687.5 CCU99980.1 - 0.0036 16.0 0.1 3.2 6.3 0.0 3.1 2 1 1 3 3 3 2 beta-propeller of ELYS nucleoporin Cytochrom_D1 PF02239.16 CCU99980.1 - 0.055 12.0 3.8 0.5 8.8 0.1 3.4 4 0 0 4 4 4 0 Cytochrome D1 heme domain DEAD PF00270.29 CCU99981.1 - 4.2e-46 156.9 0.1 6.4e-46 156.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCU99981.1 - 3.4e-25 88.6 0.0 2.9e-24 85.5 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCU99981.1 - 2.4e-18 66.1 0.5 4.1e-18 65.4 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCU99981.1 - 0.00022 21.3 0.0 0.00038 20.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.32 CCU99982.1 - 3.6e-39 132.0 14.2 2.5e-07 31.3 0.0 11.8 13 0 0 13 13 13 6 WD domain, G-beta repeat Utp12 PF04003.12 CCU99982.1 - 2.5e-20 72.8 0.1 4.2e-20 72.1 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CCU99982.1 - 1.7e-17 63.5 0.0 0.0046 17.2 0.0 8.8 3 2 6 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCU99982.1 - 5.7e-05 22.2 0.3 1.6 7.6 0.1 5.3 4 2 1 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CCU99982.1 - 0.00031 20.2 0.0 0.1 11.9 0.0 3.5 4 0 0 4 4 4 1 WD40-like domain eIF2A PF08662.11 CCU99982.1 - 0.0015 18.4 0.3 1.5 8.7 0.1 4.8 3 1 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CCU99982.1 - 0.0075 15.0 0.2 3.4 6.2 0.0 3.6 3 1 0 3 3 3 1 Nucleoporin Nup120/160 DUF1987 PF09345.10 CCU99982.1 - 0.034 13.8 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) DUF1513 PF07433.11 CCU99982.1 - 0.05 12.7 0.1 0.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) PQQ_3 PF13570.6 CCU99982.1 - 0.11 13.0 3.8 11 6.6 0.1 5.4 5 1 1 6 6 6 0 PQQ-like domain Utp21 PF04192.12 CCU99982.1 - 0.21 11.1 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Cyclin_N PF00134.23 CCU99983.1 - 9.6e-14 51.2 0.1 1.6e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCU99983.1 - 3.6e-08 33.9 0.6 6.5e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 Cyclin FANCI_S4 PF14678.6 CCU99984.1 - 2.2e-05 23.7 1.9 2.2e-05 23.7 1.9 1.5 2 0 0 2 2 2 1 FANCI solenoid 4 DUF148 PF02520.17 CCU99984.1 - 0.0018 18.4 7.4 0.11 12.6 0.1 2.4 1 1 1 2 2 2 1 Domain of unknown function DUF148 IFT57 PF10498.9 CCU99984.1 - 0.01 14.8 4.6 0.015 14.3 4.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Csa1 PF06023.12 CCU99984.1 - 0.011 15.1 0.5 0.017 14.5 0.5 1.2 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 FAM184 PF15665.5 CCU99984.1 - 0.011 15.5 5.3 0.017 14.9 5.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DUF713 PF05218.14 CCU99984.1 - 0.014 15.1 0.8 0.021 14.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF713) OmpH PF03938.14 CCU99984.1 - 0.019 15.3 10.4 0.16 12.3 10.1 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ApoLp-III PF07464.11 CCU99984.1 - 0.031 14.4 10.9 0.066 13.3 10.2 1.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 CCU99984.1 - 0.037 14.6 2.5 0.43 11.2 1.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) GlutR_dimer PF00745.20 CCU99984.1 - 0.058 13.9 1.5 0.27 11.7 1.2 2.3 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Noelin-1 PF12308.8 CCU99984.1 - 0.085 12.9 2.7 0.24 11.4 1.2 2.4 3 0 0 3 3 3 0 Neurogenesis glycoprotein FUSC PF04632.12 CCU99984.1 - 0.17 10.4 0.1 0.22 10.0 0.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family PRKG1_interact PF15898.5 CCU99984.1 - 0.2 12.6 6.1 0.31 12.0 5.8 1.5 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Exonuc_VII_L PF02601.15 CCU99984.1 - 0.23 11.0 3.9 0.31 10.6 3.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 CCU99984.1 - 0.31 9.9 8.6 0.6 8.9 8.1 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein MbeD_MobD PF04899.12 CCU99984.1 - 0.36 11.0 5.8 1.2 9.3 5.8 1.9 1 1 0 1 1 1 0 MbeD/MobD like Muted PF14942.6 CCU99984.1 - 0.41 11.0 5.0 0.5 10.7 3.9 1.8 2 0 0 2 2 1 0 Organelle biogenesis, Muted-like protein CLZ PF16526.5 CCU99984.1 - 0.44 10.9 4.9 2.5 8.5 0.8 2.7 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TipAS PF07739.13 CCU99984.1 - 1.5 9.4 6.0 34 5.0 4.8 2.3 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain FBPase PF00316.20 CCU99985.1 - 9.3e-71 237.2 0.3 1.2e-70 236.8 0.3 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 CCU99985.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Inositol monophosphatase family DUF4367 PF14285.6 CCU99985.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) Amino_oxidase PF01593.24 CCU99986.1 - 7.3e-25 88.2 0.0 9e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CCU99986.1 - 1.5e-11 44.3 0.0 3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CCU99986.1 - 3e-06 27.1 0.1 5.1e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CCU99986.1 - 0.00018 20.8 0.0 0.0052 16.1 0.0 2.7 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.6 CCU99986.1 - 0.0034 17.4 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CCU99986.1 - 0.0067 15.7 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CCU99986.1 - 0.014 14.2 0.1 0.22 10.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 CCU99986.1 - 0.038 13.3 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UCR_14kD PF02271.16 CCU99987.1 - 3e-39 133.0 1.4 3.5e-39 132.8 1.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit SMC_hinge PF06470.13 CCU99987.1 - 0.041 14.2 0.1 0.066 13.5 0.1 1.3 1 1 0 1 1 1 0 SMC proteins Flexible Hinge Domain Solute_trans_a PF03619.16 CCU99988.1 - 6.1e-08 32.5 0.0 6.9e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha RINT1_TIP1 PF04437.13 CCU99990.1 - 5.5e-73 246.6 0.0 1.1e-72 245.5 0.0 1.5 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Translin PF01997.16 CCU99990.1 - 6.4e-27 94.9 0.5 1.6e-25 90.3 0.5 2.7 1 1 0 1 1 1 1 Translin family eIF3_subunit PF08597.10 CCU99991.1 - 0.13 12.1 11.9 0.2 11.6 11.9 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Na_trans_assoc PF06512.13 CCU99991.1 - 0.26 11.6 8.9 0.38 11.0 8.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated CDC45 PF02724.14 CCU99991.1 - 5.3 5.2 6.8 6.7 4.9 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Borrelia_P83 PF05262.11 CCU99992.1 - 0.28 9.6 28.9 0.005 15.4 18.0 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein Nop53 PF07767.11 CCU99992.1 - 7 5.9 53.4 0.35 10.2 35.5 2.6 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) MCM PF00493.23 CCU99993.1 - 1.1e-96 322.3 0.0 1.6e-96 321.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCU99993.1 - 1.3e-34 118.7 0.0 2.5e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCU99993.1 - 8.5e-22 77.4 0.3 1.8e-21 76.4 0.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCU99993.1 - 2.1e-13 50.7 0.0 5.9e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCU99993.1 - 6.2e-08 32.3 0.0 1.1e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CCU99993.1 - 0.0019 18.1 0.0 0.0049 16.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCU99993.1 - 0.0068 16.1 0.0 0.019 14.6 0.0 1.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 CCU99993.1 - 0.028 14.4 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF1635 PF07795.11 CCU99993.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DEAD PF00270.29 CCU99993.1 - 0.29 10.9 1.1 26 4.5 0.1 2.5 1 1 0 2 2 2 0 DEAD/DEAH box helicase Ras PF00071.22 CCU99994.1 - 3.9e-62 208.6 0.2 4.7e-62 208.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCU99994.1 - 6.3e-34 116.8 0.1 9.9e-34 116.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCU99994.1 - 9.3e-13 48.0 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCU99994.1 - 3.3e-06 27.2 0.1 4.6e-06 26.7 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCU99994.1 - 0.00029 20.5 0.2 0.0026 17.3 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCU99994.1 - 0.00074 19.5 0.3 0.22 11.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CCU99994.1 - 0.0011 18.4 0.1 0.002 17.5 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CCU99994.1 - 0.0067 16.7 0.0 0.057 13.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 CCU99994.1 - 0.0096 15.4 0.0 0.016 14.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CCU99994.1 - 0.012 16.0 0.1 0.02 15.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 CCU99994.1 - 0.015 15.0 0.0 0.061 13.1 0.0 1.9 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CCU99994.1 - 0.033 14.7 0.2 0.047 14.2 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 CCU99994.1 - 0.039 14.2 0.1 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CCU99994.1 - 0.047 13.4 0.2 0.11 12.3 0.0 1.7 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 CCU99994.1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AEP1 PF17049.5 CCU99994.1 - 0.073 12.1 0.1 0.096 11.8 0.1 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 MCM PF00493.23 CCU99994.1 - 0.093 11.8 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain TniB PF05621.11 CCU99994.1 - 0.095 12.1 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 CCU99994.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 CCU99994.1 - 0.11 12.3 0.7 0.17 11.6 0.6 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system UQ_con PF00179.26 CCU99995.1 - 4.3e-40 136.6 0.0 4.6e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCU99995.1 - 4.5e-05 23.2 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 CCU99995.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Xpo1 PF08389.12 CCU99996.1 - 3.5e-23 82.3 0.0 9.9e-23 80.8 0.0 1.8 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.19 CCU99996.1 - 2.6e-08 33.6 0.1 6.4e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain SopA_C PF13979.6 CCU99996.1 - 0.056 13.2 1.3 0.12 12.1 0.1 2.2 3 0 0 3 3 3 0 SopA-like catalytic domain Importin_rep PF18773.1 CCU99996.1 - 0.11 12.2 0.3 0.22 11.3 0.3 1.5 1 0 0 1 1 1 0 Importin 13 repeat RTP1_C1 PF10363.9 CCU99996.1 - 0.12 12.6 0.0 0.72 10.1 0.0 2.4 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 CCU99996.1 - 0.12 12.2 0.0 43 4.1 0.0 4.5 5 0 0 5 5 5 0 UME (NUC010) domain AAA PF00004.29 CCU99997.1 - 3e-41 141.0 0.0 5e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCU99997.1 - 4.4e-11 42.4 0.0 1.5e-10 40.7 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain Vps4_C PF09336.10 CCU99997.1 - 3.6e-09 36.5 0.5 1.5e-08 34.5 0.3 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 CCU99997.1 - 7.3e-06 26.5 0.9 0.00031 21.2 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCU99997.1 - 8.6e-06 26.1 0.1 0.011 16.0 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 CCU99997.1 - 1.5e-05 25.0 0.0 5e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MIT PF04212.18 CCU99997.1 - 2.3e-05 24.4 1.7 2.3e-05 24.4 1.7 1.8 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 CCU99997.1 - 0.00015 21.5 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CCU99997.1 - 0.00021 21.1 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 CCU99997.1 - 0.0005 19.9 0.1 0.049 13.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CCU99997.1 - 0.00056 19.9 0.0 0.0014 18.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CCU99997.1 - 0.00099 19.3 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CCU99997.1 - 0.001 19.2 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 CCU99997.1 - 0.0011 18.6 0.1 0.12 12.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CCU99997.1 - 0.0015 17.7 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 CCU99997.1 - 0.0016 17.7 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 CCU99997.1 - 0.0034 17.7 0.0 0.017 15.5 0.0 2.1 2 0 0 2 2 2 1 RNA helicase Sigma54_activat PF00158.26 CCU99997.1 - 0.0037 17.0 0.0 0.084 12.6 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 CCU99997.1 - 0.0037 17.8 0.0 0.0094 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CCU99997.1 - 0.008 16.6 0.1 0.043 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CCU99997.1 - 0.0081 15.5 0.4 1.9 7.8 0.0 2.7 2 1 1 3 3 3 1 KaiC Mg_chelatase PF01078.21 CCU99997.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 CCU99997.1 - 0.034 13.6 0.0 5.5 6.4 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein CPT PF07931.12 CCU99997.1 - 0.072 12.9 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein ATPase_2 PF01637.18 CCU99997.1 - 0.077 12.9 0.0 1.5 8.7 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 CCU99997.1 - 0.083 13.0 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3543 PF12063.8 CCU99997.1 - 0.097 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) AAA_7 PF12775.7 CCU99997.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region Torsin PF06309.11 CCU99997.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_11 PF13086.6 CCU99997.1 - 0.17 11.7 0.3 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain PLDc_2 PF13091.6 CCU99998.1 - 6.6e-13 48.7 0.2 3.8e-07 30.1 0.0 3.2 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 CCU99998.1 - 1.6e-12 47.0 0.2 2.8e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.24 CCU99998.1 - 0.00022 21.2 1.8 0.00037 20.4 0.1 2.1 2 0 0 2 2 2 1 PX domain PH PF00169.29 CCU99998.1 - 0.05 14.1 0.2 0.1 13.1 0.2 1.6 1 0 0 1 1 1 0 PH domain Citrate_synt PF00285.21 CCU99999.1 - 1.1e-96 324.1 0.0 1.4e-96 323.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Sec20 PF03908.13 CCV00000.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Sec20 Use1 PF09753.9 CCV00000.1 - 0.21 11.3 0.4 0.22 11.2 0.4 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 Rhomboid PF01694.22 CCV00001.1 - 0.00036 20.6 15.7 0.00036 20.5 2.5 2.6 2 1 1 3 3 3 2 Rhomboid family KilA-N PF04383.13 CCV00002.1 - 0.0023 17.8 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 KilA-N domain Abhydrolase_3 PF07859.13 CCV00003.1 - 7.5e-20 71.7 0.0 1.3e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Glucan_synthase PF02364.15 CCV00004.1 - 0 1262.0 0.0 0 1261.0 0.0 1.5 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CCV00004.1 - 4.8e-41 140.1 0.2 1.4e-40 138.6 0.2 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 p450 PF00067.22 CCV00005.1 - 9e-51 173.0 0.0 1.2e-50 172.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tfb4 PF03850.14 CCV00006.1 - 3.2e-10 40.0 0.0 3.6e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Cyclin_N PF00134.23 CCV00007.1 - 2.4e-08 33.8 0.1 3.2e-07 30.1 0.1 2.3 1 1 0 1 1 1 1 Cyclin, N-terminal domain Histone PF00125.24 CCV00008.1 - 9.4e-24 84.2 0.6 1.2e-23 83.9 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCV00008.1 - 1.4e-06 28.5 0.1 2.9e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CCV00008.1 - 0.0004 20.8 0.0 0.00063 20.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A NFACT-R_2 PF18297.1 CCV00008.1 - 0.032 14.4 0.1 0.054 13.7 0.1 1.4 1 0 0 1 1 1 0 NFACT protein RNA binding domain DUF1018 PF06252.12 CCV00008.1 - 0.041 14.9 0.3 0.07 14.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) CENP-W PF15510.6 CCV00008.1 - 0.06 13.6 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 CENP-W protein RP-C PF03428.13 CCV00008.1 - 0.061 13.0 0.2 0.28 10.8 0.2 1.9 1 1 0 1 1 1 0 Replication protein C N-terminal domain Bt_P21 PF05560.11 CCV00008.1 - 0.088 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein YscO-like PF16789.5 CCV00008.1 - 0.11 12.5 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein Histone_H2A_C PF16211.5 CCV00009.1 - 9.3e-19 66.9 0.9 1.7e-18 66.1 0.9 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CCV00009.1 - 3.8e-17 62.9 0.0 5e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCV00009.1 - 8.9e-06 25.9 0.0 1.3e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Iso_dh PF00180.20 CCV00010.1 - 6.5e-80 268.9 0.0 7.9e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.20 CCV00011.1 - 1.5e-100 336.8 0.0 1.8e-100 336.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RRM_1 PF00076.22 CCV00012.1 - 1e-17 63.7 0.0 1.5e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCV00012.1 - 0.0044 16.6 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCV00012.1 - 0.24 11.3 0.0 0.44 10.4 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif Ribosomal_L18 PF17135.4 CCV00013.1 - 1.7e-90 301.5 2.2 1.9e-90 301.3 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CCV00013.1 - 0.00065 20.4 0.0 0.0016 19.1 0.0 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Adenylate_cycl PF01295.18 CCV00013.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I LisH PF08513.11 CCV00014.1 - 0.00041 20.2 0.0 0.00082 19.3 0.0 1.5 1 0 0 1 1 1 1 LisH DUF1424 PF07232.11 CCV00014.1 - 0.01 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative rep protein (DUF1424) Sec62 PF03839.16 CCV00014.1 - 7.8 5.9 6.2 81 2.6 5.3 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 Adap_comp_sub PF00928.21 CCV00015.1 - 9.7e-90 300.5 0.1 1.8e-89 299.6 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CCV00015.1 - 4.9e-07 29.8 0.1 8.8e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RhoGEF PF00621.20 CCV00016.1 - 3e-24 86.3 0.0 4.5e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 CCV00016.1 - 0.058 13.9 0.0 0.14 12.7 0.0 1.7 2 0 0 2 2 2 0 PH domain Methyltr_RsmB-F PF01189.17 CCV00017.1 - 2.9e-22 79.3 0.0 2.2e-21 76.5 0.0 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CCV00017.1 - 0.0012 18.9 0.0 0.0021 18.2 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Phlebovirus_G2 PF07245.11 CCV00017.1 - 0.025 13.1 0.0 0.032 12.7 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 MTS PF05175.14 CCV00017.1 - 0.22 11.1 0.0 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain ApbA_C PF08546.11 CCV00018.1 - 4.2e-19 69.0 0.0 7.1e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CCV00018.1 - 8.6e-09 35.2 0.3 5.1e-08 32.7 0.3 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HbrB PF08539.11 CCV00019.1 - 1.4e-44 152.0 0.0 2.5e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 HbrB-like PMSR PF01625.21 CCV00020.1 - 5.7e-58 195.4 0.6 6.7e-58 195.2 0.6 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Vsr PF03852.15 CCV00020.1 - 0.26 11.2 1.0 2.6 8.0 0.2 2.7 2 1 1 3 3 3 0 DNA mismatch endonuclease Vsr UQ_con PF00179.26 CCV00021.1 - 4.9e-21 74.8 0.0 5.4e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DIOX_N PF14226.6 CCV00022.1 - 4.2e-13 50.1 0.0 7.2e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CCV00022.1 - 7.5e-12 45.6 0.0 3.8e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FRB_dom PF08771.11 CCV00023.1 - 0.21 12.0 0.0 0.39 11.1 0.0 1.4 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain Peptidase_S10 PF00450.22 CCV00025.1 - 1.3e-100 337.7 0.0 1.8e-100 337.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase IBN_N PF03810.19 CCV00025.1 - 9.9e-09 35.0 0.0 5.5e-08 32.6 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CCV00025.1 - 0.16 12.0 0.0 0.53 10.3 0.0 1.9 1 0 0 1 1 1 0 Exportin 1-like protein DUF3732 PF12532.8 CCV00025.1 - 0.24 10.9 0.1 0.49 9.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) HEAT_2 PF13646.6 CCV00025.1 - 0.61 10.5 14.5 1.2 9.6 0.4 4.6 5 0 0 5 5 5 0 HEAT repeats ATP-synt_Eps PF04627.13 CCV00025.1 - 0.68 10.0 2.7 0.99 9.4 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ATP synthase epsilon chain SNF2_N PF00176.23 CCV00026.1 - 8.8e-63 212.1 0.0 1.2e-62 211.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCV00026.1 - 2.5e-09 37.5 0.0 3.5e-08 33.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 CCV00026.1 - 2.9e-06 27.1 8.8 5.9e-06 26.1 8.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 CCV00026.1 - 4e-05 23.7 0.0 0.00036 20.6 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 CCV00026.1 - 6.9e-05 22.6 7.6 0.00017 21.4 7.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CCV00026.1 - 0.002 18.1 4.0 0.0051 16.8 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CCV00026.1 - 0.0022 17.9 7.7 0.0044 16.8 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCV00026.1 - 0.0038 17.5 10.0 0.0091 16.3 10.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-piccolo PF05715.13 CCV00026.1 - 0.012 15.8 6.6 0.034 14.3 1.2 2.7 2 0 0 2 2 2 0 Piccolo Zn-finger zf-UDP PF14569.6 CCV00026.1 - 0.018 15.1 2.1 0.043 13.9 2.1 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 CCV00026.1 - 4.5 7.2 7.7 10 6.0 7.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 CCV00026.1 - 7.3 6.5 10.0 31 4.5 10.0 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 2OG-FeII_Oxy_2 PF13532.6 CCV00027.1 - 1.5e-07 31.8 0.0 2.1e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 CCV00028.1 - 1.9e-43 148.7 0.0 2.7e-27 95.8 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCV00028.1 - 3.9e-21 75.5 0.0 2.9e-14 53.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCV00028.1 - 0.033 13.5 0.0 25 4.1 0.0 3.0 3 0 0 3 3 3 0 Kinase-like Ribosomal_S6e PF01092.19 CCV00030.1 - 6.5e-53 178.0 0.0 1.1e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.12 CCV00031.1 - 1.9e-30 104.7 0.6 3e-30 104.1 0.6 1.3 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CCV00031.1 - 1.2e-13 51.0 0.2 1.8e-13 50.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 CCV00031.1 - 0.00087 19.2 0.1 0.0022 17.9 0.1 1.7 1 1 0 2 2 2 1 'Paired box' domain HTH_32 PF13565.6 CCV00031.1 - 0.013 16.1 0.0 0.027 15.1 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain zf-H2C2_2 PF13465.6 CCV00032.1 - 2.1e-24 84.8 37.5 2.5e-07 30.8 2.2 6.7 6 0 0 6 6 5 4 Zinc-finger double domain IPK PF03770.16 CCV00032.1 - 9.1e-23 81.1 0.0 1.6e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase zf-C2H2 PF00096.26 CCV00032.1 - 7.7e-19 67.0 50.0 2.5e-05 24.5 0.3 8.2 8 0 0 8 8 7 6 Zinc finger, C2H2 type Lipase_3 PF01764.25 CCV00032.1 - 2.1e-17 63.3 0.0 3.8e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) zf-C2H2_4 PF13894.6 CCV00032.1 - 6.8e-09 35.8 52.7 0.0047 17.6 0.7 8.4 8 0 0 8 8 7 4 C2H2-type zinc finger FOXP-CC PF16159.5 CCV00032.1 - 0.0005 20.6 28.2 0.15 12.7 0.6 6.2 5 2 1 6 6 6 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CCV00032.1 - 0.0011 19.2 7.0 0.12 12.7 0.1 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding DUF676 PF05057.14 CCV00032.1 - 0.036 13.6 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) zf-C2H2_11 PF16622.5 CCV00032.1 - 0.083 12.7 7.6 1.4 8.8 0.4 4.0 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_UBZ PF18439.1 CCV00032.1 - 2 8.0 9.4 0.2 11.3 0.2 3.6 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn_ribbon_SprT PF17283.2 CCV00032.1 - 6 6.9 7.5 15 5.6 0.5 3.8 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-C2H2_aberr PF17017.5 CCV00032.1 - 9 6.4 11.5 7.8 6.6 0.5 3.9 3 1 1 4 4 4 0 Aberrant zinc-finger MAP65_ASE1 PF03999.12 CCV00033.1 - 8e-65 219.7 0.1 4.5e-63 213.9 0.0 2.9 1 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Vps52 PF04129.12 CCV00033.1 - 3.7e-24 85.4 0.0 1.3e-21 76.9 0.0 3.2 2 1 0 2 2 2 1 Vps52 / Sac2 family CdvA PF18822.1 CCV00033.1 - 0.0025 17.7 4.2 1.1 9.0 0.0 3.0 3 0 0 3 3 2 2 CdvA-like coiled-coil domain DUF1664 PF07889.12 CCV00033.1 - 0.0031 17.6 0.4 3.9 7.5 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CCV00033.1 - 0.0061 16.6 1.2 4.7 7.3 0.0 3.3 3 0 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 CCV00033.1 - 0.0063 16.5 1.0 0.0063 16.5 1.0 2.7 3 0 0 3 3 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BST2 PF16716.5 CCV00033.1 - 0.013 16.1 10.1 0.099 13.2 1.8 4.3 4 0 0 4 4 3 0 Bone marrow stromal antigen 2 Spc7 PF08317.11 CCV00033.1 - 0.014 14.2 9.5 0.054 12.4 0.4 3.4 4 0 0 4 4 4 0 Spc7 kinetochore protein COG2 PF06148.11 CCV00033.1 - 0.017 15.2 2.4 3.5 7.7 0.3 3.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 USP8_interact PF08941.10 CCV00033.1 - 0.028 14.2 1.8 0.12 12.2 0.3 2.6 2 0 0 2 2 2 0 USP8 interacting NPV_P10 PF05531.12 CCV00033.1 - 0.053 14.0 0.3 10 6.7 0.1 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4355 PF14265.6 CCV00033.1 - 0.087 13.1 0.1 0.42 10.9 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DASH_Duo1 PF08651.10 CCV00033.1 - 0.11 12.3 1.4 0.39 10.5 0.3 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 GAS PF13851.6 CCV00033.1 - 0.11 11.8 6.2 0.12 11.7 0.6 3.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding PspB PF06667.12 CCV00033.1 - 0.15 12.1 1.4 0.68 10.0 1.4 2.1 1 0 0 1 1 1 0 Phage shock protein B DUF5082 PF16888.5 CCV00033.1 - 0.15 12.3 2.4 6.2 7.1 0.0 3.4 3 0 0 3 3 2 0 Domain of unknown function (DUF5082) Tmemb_cc2 PF10267.9 CCV00033.1 - 0.16 11.1 1.5 1.8 7.6 0.1 2.7 3 0 0 3 3 2 0 Predicted transmembrane and coiled-coil 2 protein FAA_hydro_N_2 PF18288.1 CCV00033.1 - 0.17 12.3 10.3 4.9 7.7 0.2 4.6 4 0 0 4 4 2 0 Fumarylacetoacetase N-terminal domain 2 DUF4315 PF14193.6 CCV00033.1 - 0.17 11.9 0.9 0.84 9.7 0.9 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) DUF4201 PF13870.6 CCV00033.1 - 0.2 11.4 3.5 13 5.5 2.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Csm1_N PF18504.1 CCV00033.1 - 0.23 11.8 4.1 1.6 9.1 1.1 3.3 3 0 0 3 3 2 0 Csm1 N-terminal domain IFT57 PF10498.9 CCV00033.1 - 0.48 9.3 4.9 1.4 7.8 0.8 3.0 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 TolA_bind_tri PF16331.5 CCV00033.1 - 0.52 10.4 8.3 7.9 6.6 3.4 3.6 3 0 0 3 3 2 0 TolA binding protein trimerisation BRE1 PF08647.11 CCV00033.1 - 0.63 10.2 7.5 0.31 11.1 2.3 3.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Phage_GPO PF05929.11 CCV00033.1 - 0.66 9.6 18.6 0.26 10.9 4.8 3.5 4 0 0 4 4 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Prok-TraM PF09228.10 CCV00033.1 - 0.91 9.9 4.8 0.32 11.4 0.3 2.7 3 0 0 3 3 1 0 Prokaryotic Transcriptional repressor TraM Med3 PF11593.8 CCV00033.1 - 1.2 8.3 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 1 0 Mediator complex subunit 3 fungal EzrA PF06160.12 CCV00033.1 - 1.2 7.2 3.1 0.8 7.8 0.2 2.1 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA HrpB7 PF09486.10 CCV00033.1 - 1.4 9.3 36.3 1.3 9.4 2.3 4.8 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Spc24 PF08286.11 CCV00033.1 - 1.4 9.2 3.7 3.1 8.1 1.2 2.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SlyX PF04102.12 CCV00033.1 - 1.4 9.6 15.0 2.6 8.7 2.4 5.4 5 1 1 6 6 4 0 SlyX DUF641 PF04859.12 CCV00033.1 - 1.6 9.1 6.3 3.7 7.9 0.5 3.8 4 0 0 4 4 3 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 CCV00033.1 - 1.7 8.8 5.2 3.2 7.9 0.1 3.7 5 0 0 5 5 4 0 Fibrinogen alpha/beta chain family YabA PF06156.13 CCV00033.1 - 1.8 9.3 4.6 19 5.9 0.1 3.9 4 1 0 4 4 2 0 Initiation control protein YabA ADIP PF11559.8 CCV00033.1 - 1.8 8.6 15.9 0.11 12.6 2.4 3.3 4 0 0 4 4 2 0 Afadin- and alpha -actinin-Binding Cep57_CLD_2 PF14197.6 CCV00033.1 - 3.4 7.8 10.4 0.43 10.7 2.7 3.4 3 0 0 3 3 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 CCV00033.1 - 4 7.3 9.2 5.5 6.8 1.8 3.7 3 0 0 3 3 3 0 Septum formation initiator THOC7 PF05615.13 CCV00033.1 - 5.9 7.2 17.8 0.23 11.8 0.2 4.6 4 1 0 4 4 4 0 Tho complex subunit 7 OmpH PF03938.14 CCV00033.1 - 8.8 6.7 11.3 0.42 11.0 0.9 3.6 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) LRR_4 PF12799.7 CCV00034.1 - 9.6e-32 108.5 1.1 2.7e-05 24.5 0.1 8.6 6 2 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCV00034.1 - 3.3e-28 97.2 12.9 1.4e-08 34.4 1.5 6.2 6 1 0 6 6 6 4 Leucine rich repeat LRR_9 PF14580.6 CCV00034.1 - 7.1e-11 41.9 1.4 0.00087 18.8 0.0 4.6 1 1 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 CCV00034.1 - 7.5e-05 22.5 4.8 5.4 7.3 0.1 7.5 9 0 0 9 9 9 1 Leucine Rich repeat LRR_1 PF00560.33 CCV00034.1 - 0.15 12.7 20.5 8.1 7.4 0.1 9.6 12 2 1 13 13 13 0 Leucine Rich Repeat Lum_binding PF00677.17 CCV00035.1 - 1e-41 140.8 0.0 1.8e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain G10 PF01125.17 CCV00036.1 - 6.4e-64 214.1 1.3 7.8e-64 213.9 1.3 1.1 1 0 0 1 1 1 1 G10 protein DEP PF00610.21 CCV00037.1 - 0.00096 19.2 0.2 0.024 14.7 0.0 2.4 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RGS PF00615.19 CCV00037.1 - 0.21 11.9 0.0 0.49 10.7 0.0 1.6 1 0 0 1 1 1 0 Regulator of G protein signaling domain Hist_deacetyl PF00850.19 CCV00038.1 - 1.4e-80 271.1 0.0 1.9e-80 270.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 CCV00038.1 - 1.4e-27 96.4 0.0 2.1e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain Med20 PF08612.11 CCV00040.1 - 0.00053 19.4 0.0 0.0012 18.2 0.0 1.4 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex SIP PF04954.13 CCV00041.1 - 0.052 14.1 2.0 0.9 10.1 1.0 3.0 3 0 0 3 3 3 0 Siderophore-interacting protein JAB PF01398.21 CCV00042.1 - 1.9e-33 115.0 0.0 3e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CCV00042.1 - 1.1e-13 51.6 0.2 2.3e-13 50.6 0.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CCV00042.1 - 4.5e-07 29.7 0.0 7.6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CCV00042.1 - 0.0096 16.0 0.0 0.024 14.7 0.0 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) DUF5624 PF18538.1 CCV00042.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) NicO PF03824.16 CCV00044.1 - 1.4e-45 155.8 12.3 2e-24 86.4 0.3 3.9 4 1 0 4 4 4 3 High-affinity nickel-transport protein DUF1404 PF07185.11 CCV00044.1 - 0.012 15.3 0.5 0.012 15.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1404) EphA2_TM PF14575.6 CCV00044.1 - 0.71 10.8 9.5 31 5.5 0.0 4.1 5 0 0 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain ICMT PF04140.14 CCV00046.1 - 4.6e-27 94.3 1.0 7e-27 93.7 1.0 1.2 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CCV00046.1 - 5.1e-11 42.9 1.9 7.4e-11 42.4 1.9 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 CCV00046.1 - 0.0002 21.0 0.8 0.00023 20.8 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Amidohydro_2 PF04909.14 CCV00047.1 - 4.4e-10 39.8 0.4 9.8e-10 38.7 0.3 1.6 1 1 1 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.20 CCV00047.1 - 0.00012 21.5 0.1 0.0034 16.8 0.0 2.0 1 1 1 2 2 2 2 Amidohydrolase family ADK PF00406.22 CCV00049.1 - 2.4e-58 196.5 0.1 3e-58 196.2 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CCV00049.1 - 1.9e-22 80.1 0.3 4.8e-22 78.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CCV00049.1 - 1.5e-16 60.1 0.0 4.1e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CCV00049.1 - 1.9e-06 28.1 0.0 3.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCV00049.1 - 5.2e-05 23.8 0.0 0.00014 22.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 CCV00049.1 - 0.017 14.8 0.1 2.4 7.8 0.0 2.8 2 1 1 3 3 3 0 Thymidylate kinase AAA PF00004.29 CCV00049.1 - 0.024 15.1 0.0 0.053 13.9 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CCV00049.1 - 0.031 13.6 0.0 0.073 12.3 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 CCV00049.1 - 0.09 12.8 0.1 0.3 11.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CCV00049.1 - 0.13 12.0 0.2 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ParA PF10609.9 CCV00050.1 - 6.9e-87 291.0 0.0 8.5e-87 290.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CCV00050.1 - 3.2e-06 27.2 0.0 3.7e-05 23.8 0.0 2.6 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 CCV00050.1 - 0.00013 21.3 2.3 0.00077 18.7 0.5 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 CCV00050.1 - 0.00071 19.5 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CCV00050.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCV00050.1 - 0.015 15.7 0.2 0.035 14.5 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_26 PF13500.6 CCV00050.1 - 0.058 13.2 0.2 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain MipZ PF09140.11 CCV00050.1 - 0.063 12.6 0.3 0.23 10.7 0.3 1.9 1 1 0 1 1 1 0 ATPase MipZ RsgA_GTPase PF03193.16 CCV00050.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 CCV00050.1 - 0.18 11.0 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TPR_1 PF00515.28 CCV00051.1 - 2.7e-18 64.9 16.1 0.0024 17.6 0.1 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 CCV00051.1 - 1.3e-17 62.4 37.8 0.0017 18.3 0.0 10.3 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 CCV00051.1 - 8.1e-16 56.8 5.3 0.0053 16.9 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CCV00051.1 - 3.7e-12 46.0 58.7 3.3e-05 24.4 0.4 11.4 7 2 4 12 12 12 4 Tetratricopeptide repeat TPR_12 PF13424.6 CCV00051.1 - 6.6e-09 35.9 34.8 6.4e-06 26.4 1.5 7.5 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCV00051.1 - 1.9e-08 34.1 12.0 1.6 9.2 0.0 8.3 9 1 1 10 10 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 CCV00051.1 - 5.7e-07 29.1 24.6 0.24 11.5 0.0 8.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CCV00051.1 - 1e-06 29.1 40.3 0.011 16.2 0.2 9.0 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 CCV00051.1 - 1.9e-05 25.2 65.4 0.0035 18.0 0.5 10.2 7 2 3 11 11 11 4 Tetratricopeptide repeat TPR_11 PF13414.6 CCV00051.1 - 0.00014 21.4 22.7 0.072 12.8 0.0 8.6 10 1 1 11 11 11 2 TPR repeat TPR_6 PF13174.6 CCV00051.1 - 0.0028 18.2 23.8 0.11 13.1 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 CCV00051.1 - 0.13 12.1 28.3 1.4 8.9 0.1 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 CCV00051.1 - 0.57 9.9 7.7 9.8 5.8 0.2 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain Ydr279_N PF17745.1 CCV00053.1 - 8.2e-10 38.8 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 CCV00053.1 - 2.6e-05 24.4 0.0 5.9e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF455 PF04305.14 CCV00054.1 - 1.1e-86 290.4 0.0 1.4e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) 2Fe-2S_thioredx PF01257.19 CCV00056.1 - 7.7e-54 181.5 1.0 1e-53 181.1 1.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.11 CCV00056.1 - 0.0079 16.6 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1636) adh_short PF00106.25 CCV00057.1 - 3.4e-15 56.0 0.5 2.6e-14 53.1 0.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCV00057.1 - 6.1e-07 29.2 0.1 0.014 14.9 0.1 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCV00057.1 - 0.00011 22.1 0.6 0.0019 18.2 0.3 2.2 2 0 0 2 2 2 1 KR domain RNA_polI_A34 PF08208.11 CCV00058.1 - 3.4e-07 30.6 0.0 3.4e-07 30.6 0.0 2.5 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 GST_C_6 PF17171.4 CCV00059.1 - 7.3e-07 28.9 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CCV00059.1 - 0.00012 22.4 0.1 0.00025 21.4 0.1 1.6 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 CCV00059.1 - 0.059 13.4 1.5 0.12 12.5 0.4 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1g PF09334.11 CCV00061.1 - 1.5e-89 300.5 0.0 1.9e-88 296.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CCV00061.1 - 1.1e-17 63.6 0.2 2e-09 36.3 0.0 2.7 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CCV00061.1 - 2.7e-08 33.5 0.0 0.0054 16.1 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 CCV00061.1 - 0.0012 18.8 0.1 0.0025 17.8 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 CCV00061.1 - 0.013 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) ApbA PF02558.16 CCV00062.1 - 8.2e-31 106.7 0.0 1.1e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CCV00062.1 - 1e-22 80.6 0.0 1.8e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_7 PF13241.6 CCV00062.1 - 0.048 14.1 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding tRNA-synt_2 PF00152.20 CCV00063.1 - 2.8e-75 253.3 0.6 9.4e-75 251.6 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 CCV00063.1 - 1.7e-17 63.4 0.4 4.1e-17 62.1 0.1 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2156) tRNA-synt_2d PF01409.20 CCV00063.1 - 0.00033 20.2 0.3 0.15 11.5 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 CCV00063.1 - 0.0038 17.2 0.0 0.0084 16.1 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Acetyltransf_9 PF13527.7 CCV00063.1 - 0.12 12.4 0.2 5.3 7.1 0.1 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Synaptobrevin PF00957.21 CCV00064.1 - 4.5e-23 80.9 0.0 5.7e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CCV00064.1 - 1.8e-16 59.9 0.0 3.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Snf7 PF03357.21 CCV00065.1 - 6.1e-14 52.0 2.4 9.5e-14 51.4 2.4 1.3 1 0 0 1 1 1 1 Snf7 DUF677 PF05055.12 CCV00065.1 - 0.11 11.3 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) GAS PF13851.6 CCV00065.1 - 0.15 11.4 1.2 9.1 5.6 1.2 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding HA2 PF04408.23 CCV00066.1 - 1e-18 67.6 0.1 2.6e-18 66.3 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CCV00066.1 - 1.5e-17 63.7 0.0 1.2e-16 60.8 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CCV00066.1 - 3.5e-12 46.6 0.0 6.4e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCV00066.1 - 0.00054 19.8 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SCA7 PF08313.12 CCV00067.1 - 1.6e-28 98.4 0.1 3.7e-28 97.2 0.1 1.6 1 0 0 1 1 1 1 SCA7, zinc-binding domain Sgf11 PF08209.11 CCV00067.1 - 0.1 12.2 0.3 0.24 11.0 0.3 1.6 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) adh_short PF00106.25 CCV00068.1 - 0.18 11.2 0.1 0.46 9.9 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase DASH_Dad2 PF08654.10 CCV00069.1 - 3.8e-22 78.6 1.1 5.1e-22 78.2 1.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DUF3418 PF11898.8 CCV00069.1 - 0.016 13.9 0.8 0.018 13.7 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) DUF21 PF01595.20 CCV00069.1 - 0.05 13.3 0.3 0.061 13.0 0.3 1.1 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Ribosomal_S30 PF04758.14 CCV00070.1 - 1.4e-30 105.3 6.1 1.5e-30 105.2 6.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 zf-Tim10_DDP PF02953.15 CCV00072.1 - 1.4e-18 66.3 0.9 1.6e-18 66.1 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Asp PF00026.23 CCV00073.2 - 6e-71 239.4 0.5 7.3e-71 239.2 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCV00073.2 - 5.4e-14 52.8 1.2 1.8e-11 44.6 1.2 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal DnaJ_C PF01556.18 CCV00074.1 - 6.8e-26 91.1 0.0 9.4e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCV00074.1 - 5.3e-22 77.7 0.7 8.8e-22 77.0 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCV00074.1 - 3.4e-14 53.0 12.8 5.5e-14 52.3 12.8 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CCV00074.1 - 1.9e-05 24.5 4.9 0.037 14.0 0.4 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CCV00074.1 - 0.016 15.2 4.7 2 8.5 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrom_c3_2 PF14537.6 CCV00074.1 - 2.4 8.7 12.4 0.47 10.9 8.5 1.9 2 1 0 2 2 2 0 Cytochrome c3 DZR PF12773.7 CCV00074.1 - 5.3 7.2 11.2 5.9 7.0 2.2 2.2 1 1 2 3 3 3 0 Double zinc ribbon TackOD1 PF18551.1 CCV00074.1 - 7.9 6.1 8.1 4 7.1 0.7 2.4 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 FA_hydroxylase PF04116.13 CCV00075.1 - 1.6e-20 73.8 13.4 1.6e-20 73.8 13.4 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Mur_ligase PF01225.25 CCV00075.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Response_reg PF00072.24 CCV00076.1 - 1.6e-21 76.6 0.1 7.3e-16 58.3 0.2 2.7 3 0 0 3 3 3 2 Response regulator receiver domain Amdase PF17645.1 CCV00076.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Arylmalonate decarboxylase Bim_N PF06773.11 CCV00076.1 - 4.4 7.1 5.9 4.1 7.2 1.4 2.9 2 0 0 2 2 2 0 Bim protein N-terminus NCA2 PF08637.10 CCV00077.1 - 9e-72 241.7 0.0 1.3e-71 241.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 RHH_1 PF01402.21 CCV00077.1 - 0.29 11.1 3.7 0.7 9.9 0.2 3.6 5 0 0 5 5 5 0 Ribbon-helix-helix protein, copG family NMT_C PF02799.15 CCV00078.1 - 1.2e-72 243.9 0.0 2.1e-72 243.1 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CCV00078.1 - 5.8e-72 240.8 0.0 7.9e-72 240.3 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 CCV00078.1 - 2.8e-05 24.3 0.0 0.00014 22.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 CCV00078.1 - 0.00017 21.7 0.0 0.0019 18.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Torus PF16131.5 CCV00079.1 - 9.3e-08 32.7 0.1 1.8e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 CCV00079.1 - 3e-06 27.1 3.0 6.2e-06 26.1 3.0 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CCV00079.1 - 0.00016 21.5 0.8 0.00016 21.5 0.8 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CCV00079.1 - 0.0021 18.2 0.0 0.0039 17.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 CCV00079.1 - 0.003 17.3 2.1 0.0065 16.3 2.1 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger FYVE PF01363.21 CCV00079.1 - 0.0099 16.0 0.3 0.0099 16.0 0.3 1.6 2 0 0 2 2 2 1 FYVE zinc finger DUF2256 PF10013.9 CCV00079.1 - 0.11 12.6 0.4 0.11 12.6 0.4 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-CCCH_2 PF14608.6 CCV00079.1 - 0.25 11.9 1.6 0.64 10.6 1.6 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Complex1_LYR PF05347.15 CCV00080.1 - 1.7e-07 31.2 0.7 2.8e-07 30.5 0.1 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CCV00080.1 - 0.0019 18.9 0.2 0.003 18.3 0.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Ribosomal_L31 PF01197.18 CCV00080.1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L31 HECT PF00632.25 CCV00081.1 - 8.7e-95 317.7 0.0 1.1e-94 317.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CCV00081.1 - 8.4e-35 118.5 16.7 4.9e-12 45.7 1.9 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.30 CCV00081.1 - 5.8e-16 58.7 0.1 1.5e-15 57.4 0.1 1.6 1 0 0 1 1 1 1 C2 domain Nuc_sug_transp PF04142.15 CCV00082.1 - 7.8e-10 38.4 4.2 1.1e-09 38.0 4.2 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 CCV00082.1 - 4.7e-06 26.0 10.1 7e-06 25.5 10.1 1.4 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 CCV00082.1 - 4.9e-05 22.8 14.1 4.9e-05 22.8 14.1 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 CCV00082.1 - 0.016 15.4 20.8 0.02 15.1 7.6 2.9 2 1 0 2 2 2 0 EamA-like transporter family CcmE PF03100.15 CCV00082.1 - 0.54 10.3 1.7 2 8.4 0.0 2.3 2 0 0 2 2 2 0 CcmE Hist_deacetyl PF00850.19 CCV00083.1 - 8.2e-80 268.5 0.0 1e-79 268.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Polysacc_deac_1 PF01522.21 CCV00084.1 - 4.6e-59 197.7 0.0 7.7e-30 103.3 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide deacetylase WD40 PF00400.32 CCV00085.1 - 0.0081 17.0 3.5 15 6.6 0.1 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF1214 PF06742.11 CCV00086.1 - 1.9e-10 41.1 2.4 3.8e-06 27.3 0.1 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1214) Y_Y_Y PF07495.13 CCV00086.1 - 0.028 14.4 3.0 7.5 6.6 0.0 4.2 3 1 0 3 3 3 0 Y_Y_Y domain Ribosomal_L30 PF00327.20 CCV00087.1 - 4.9e-13 48.8 0.1 6.6e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DctA-YdbH PF11739.8 CCV00087.1 - 0.088 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Dicarboxylate transport Exo_endo_phos PF03372.23 CCV00090.1 - 0.017 14.6 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DEAD PF00270.29 CCV00091.1 - 2.9e-50 170.5 0.0 6e-50 169.4 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCV00091.1 - 5.8e-22 78.1 0.0 2.1e-20 73.1 0.0 2.6 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCV00091.1 - 6.7e-05 23.0 0.0 0.00018 21.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit API5 PF05918.11 CCV00091.1 - 0.22 10.3 0.5 4.2 6.1 0.3 2.3 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Pkinase PF00069.25 CCV00092.1 - 3.3e-19 69.3 1.7 1.6e-07 31.0 0.0 3.1 1 1 2 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CCV00092.1 - 6.8e-08 32.1 0.5 0.0029 16.9 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCV00092.1 - 0.0065 15.3 0.1 0.017 14.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CCV00092.1 - 0.034 13.1 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CCV00092.1 - 0.071 12.7 0.3 5.6 6.5 0.0 2.2 1 1 0 2 2 2 0 RIO1 family TBCA PF02970.16 CCV00093.1 - 5.1e-19 68.4 0.5 5.3e-19 68.3 0.5 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A PMEI PF04043.15 CCV00093.1 - 0.014 15.7 0.1 0.015 15.7 0.1 1.0 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Plasmodium_HRP PF05403.11 CCV00094.1 - 0.018 14.9 70.9 0.03 14.1 70.9 1.2 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) SOG2 PF10428.9 CCV00094.1 - 6.9 5.7 82.8 5.9 6.0 62.5 2.4 2 0 0 2 2 2 0 RAM signalling pathway protein Asp PF00026.23 CCV00095.1 - 4.8e-107 358.0 0.0 5.5e-107 357.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCV00095.1 - 6.3e-15 55.9 0.4 3.9e-12 46.8 0.4 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CCV00095.1 - 8.2e-07 28.9 0.0 8.4e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal G-patch_2 PF12656.7 CCV00096.1 - 2.5e-24 85.1 0.3 5.8e-24 83.9 0.3 1.7 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 CCV00096.1 - 4.7e-08 32.8 1.7 9.2e-08 31.9 1.7 1.4 1 0 0 1 1 1 1 G-patch domain Glyoxalase_6 PF18029.1 CCV00096.1 - 0.059 14.2 0.3 11 6.8 0.0 2.7 2 1 0 2 2 2 0 Glyoxalase-like domain Methyltransf_12 PF08242.12 CCV00097.1 - 0.0021 18.8 0.0 0.0031 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCV00097.1 - 0.0065 17.1 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCV00097.1 - 0.11 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CCV00097.1 - 0.17 12.5 0.0 0.28 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.29 CCV00098.1 - 2.9e-36 124.8 0.0 7.3e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCV00098.1 - 4.6e-29 101.0 0.1 2.1e-26 92.4 0.1 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCV00098.1 - 1.3e-08 35.0 0.0 2.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CCV00098.1 - 0.03 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Sod_Fe_C PF02777.18 CCV00099.1 - 6.4e-34 116.2 1.0 1.1e-33 115.4 1.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CCV00099.1 - 1.6e-31 108.6 2.9 4e-31 107.3 2.9 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain G6PD_C PF02781.16 CCV00100.1 - 5.6e-106 354.0 0.0 8.2e-106 353.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CCV00100.1 - 3.2e-48 164.7 0.0 5.6e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain zf-C2H2 PF00096.26 CCV00101.1 - 8.3e-09 35.4 12.9 0.00015 22.0 2.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCV00101.1 - 1.1e-07 32.0 17.1 5.6e-05 23.4 4.5 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCV00101.1 - 0.00023 21.8 10.7 0.036 14.9 2.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCV00101.1 - 0.021 15.1 1.3 3.1 8.2 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CCV00101.1 - 0.088 13.5 0.8 0.17 12.5 0.1 1.8 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-Di19 PF05605.12 CCV00101.1 - 0.39 11.0 3.2 0.73 10.2 3.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Leo1 PF04004.13 CCV00102.1 - 4.3e-45 153.5 0.0 4.3e-45 153.5 0.0 2.5 3 0 0 3 3 3 1 Leo1-like protein Ebp2 PF05890.12 CCV00103.1 - 1.4e-86 290.4 14.8 1.4e-86 290.4 14.8 2.1 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF3561 PF12084.8 CCV00104.1 - 2.7 8.0 6.2 0.39 10.7 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) DUF747 PF05346.11 CCV00105.1 - 1.5e-112 376.2 7.7 2.2e-112 375.7 7.7 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family N2227 PF07942.12 CCV00106.1 - 9.8e-88 293.9 0.0 1.2e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein BHD_3 PF10405.9 CCV00107.1 - 1.3e-25 89.6 0.0 2.7e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 CCV00107.1 - 7.9e-23 80.8 0.0 1.7e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 CCV00107.1 - 1.4e-18 66.4 0.7 2.7e-18 65.6 0.1 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CCV00107.1 - 9.1e-17 61.8 1.3 1.6e-16 61.0 0.2 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 CCV00107.1 - 4e-10 40.1 0.7 1e-09 38.8 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily Zn_clus PF00172.18 CCV00108.1 - 0.00037 20.6 13.9 0.00084 19.4 13.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_pp85 PF04637.12 CCV00108.1 - 0.056 11.9 0.8 0.099 11.0 0.8 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) EF-G-binding_N PF07299.11 CCV00108.1 - 0.088 13.3 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal Pkinase PF00069.25 CCV00109.1 - 2.4e-69 233.6 0.0 2.9e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCV00109.1 - 3.1e-34 118.4 0.0 4.4e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCV00109.1 - 2.4e-05 23.8 0.0 6.9e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CCV00109.1 - 0.011 14.8 0.0 0.083 11.8 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CCV00109.1 - 0.1 12.5 9.3 0.025 14.5 1.1 3.1 2 2 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CCV00109.1 - 0.17 11.2 0.8 0.4 10.0 0.8 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seryl_tRNA_N PF02403.22 CCV00110.1 - 0.21 11.8 33.0 0.14 12.4 10.4 4.3 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 CCV00110.1 - 0.63 10.5 4.7 3.4 8.2 0.1 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein HlyD_2 PF12700.7 CCV00110.1 - 0.76 8.4 6.0 0.82 8.3 1.8 2.0 1 1 1 2 2 2 0 HlyD family secretion protein DUF948 PF06103.11 CCV00110.1 - 2.3 8.5 7.2 1.7 9.0 0.7 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Cep57_MT_bd PF06657.13 CCV00110.1 - 2.7 8.5 11.8 0.59 10.6 0.9 4.1 2 2 3 5 5 5 0 Centrosome microtubule-binding domain of Cep57 Kinesin PF00225.23 CCV00111.1 - 5.3e-70 236.0 0.0 4.5e-69 232.9 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CCV00111.1 - 3.2e-44 150.5 0.0 6.4e-44 149.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Pkip-1 PF06878.11 CCV00111.1 - 0.17 12.0 0.2 0.28 11.3 0.2 1.4 1 0 0 1 1 1 0 Pkip-1 protein DUF641 PF04859.12 CCV00111.1 - 0.57 10.5 7.3 0.43 10.9 1.3 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.8 CCV00111.1 - 1.6 8.8 5.5 21 5.2 0.4 2.7 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ABC_tran_CTD PF16326.5 CCV00111.1 - 5.4 7.3 13.6 2 8.7 7.4 2.9 2 1 0 3 3 3 0 ABC transporter C-terminal domain zf-ANAPC11 PF12861.7 CCV00112.1 - 7.3e-24 83.7 9.8 9.1e-24 83.3 9.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CCV00112.1 - 5.9e-20 71.3 11.5 1e-19 70.5 11.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CCV00112.1 - 5.7e-07 29.8 15.3 3.4e-06 27.3 14.0 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CCV00112.1 - 3.3e-05 23.7 10.4 8.2e-05 22.4 10.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCV00112.1 - 0.00067 19.4 16.7 0.00073 19.3 12.5 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCV00112.1 - 0.0034 17.4 7.3 0.0035 17.3 4.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CCV00112.1 - 0.014 15.5 9.6 0.84 9.8 9.6 2.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-HC5HC2H_2 PF13832.6 CCV00112.1 - 0.019 15.1 3.7 0.019 15.1 3.7 1.6 1 1 1 2 2 2 0 PHD-zinc-finger like domain RecR PF02132.15 CCV00112.1 - 0.048 13.2 3.2 0.31 10.7 1.2 2.5 2 1 0 2 2 2 0 RecR protein FANCL_C PF11793.8 CCV00112.1 - 0.09 13.0 11.9 0.73 10.0 11.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 CCV00112.1 - 0.14 12.0 4.8 0.26 11.2 4.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 CCV00112.1 - 0.16 11.8 9.4 2 8.3 9.4 2.3 1 1 0 1 1 1 0 RING-like zinc finger zf-HC5HC2H PF13771.6 CCV00112.1 - 0.19 12.0 7.8 0.64 10.3 8.1 1.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING_5 PF14634.6 CCV00112.1 - 0.49 10.4 14.6 8.9 6.4 14.6 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CCV00112.1 - 1 9.2 12.2 6.3 6.7 11.3 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CCV00112.1 - 1.2 9.0 13.3 4.5 7.2 9.1 2.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 CCV00112.1 - 1.3 9.2 11.3 0.3 11.2 7.1 2.1 2 1 0 2 2 2 0 RING-variant domain zf-RING-like PF08746.11 CCV00112.1 - 1.7 9.1 12.9 0.14 12.5 7.3 2.1 2 2 0 2 2 2 0 RING-like domain Zn-ribbon_8 PF09723.10 CCV00112.1 - 3.7 7.7 9.4 2.3 8.4 0.9 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Zn_ribbon_17 PF17120.5 CCV00112.1 - 4.6 7.0 17.7 7.2 6.3 13.1 2.8 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type AMPKBI PF04739.15 CCV00113.1 - 9.5e-28 96.3 0.5 3.5e-27 94.5 0.5 2.0 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 CCV00113.1 - 5.2e-26 90.7 0.0 9.7e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 CCV00113.1 - 0.095 13.3 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Methyltransf_23 PF13489.6 CCV00114.1 - 9.9e-11 41.7 0.0 1.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCV00114.1 - 3.5e-09 37.3 0.0 8.8e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCV00114.1 - 5.2e-09 36.6 0.1 1.6e-08 35.1 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCV00114.1 - 5.6e-09 36.6 0.1 3.1e-08 34.2 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CCV00114.1 - 0.024 15.6 0.1 0.037 15.1 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CCV00114.1 - 0.063 13.1 0.0 0.68 9.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 CCV00114.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent HAD_2 PF13419.6 CCV00115.1 - 6.3e-19 68.7 0.0 9e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCV00115.1 - 7.4e-11 42.7 0.1 1.5e-09 38.5 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCV00115.1 - 0.0029 17.6 0.0 0.0053 16.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 CCV00115.1 - 0.0075 16.7 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase tRNA-synt_1_2 PF13603.6 CCV00115.1 - 0.013 15.0 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Hydrolase_3 PF08282.12 CCV00115.1 - 0.28 10.9 0.1 0.92 9.2 0.1 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CCV00116.1 - 5.3e-15 56.0 0.0 2.2e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCV00116.1 - 2.6e-08 34.4 0.0 1.3e-07 32.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCV00116.1 - 2.8e-05 24.1 0.1 0.0001 22.3 0.1 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like ubiquitin PF00240.23 CCV00117.1 - 8.3e-15 54.3 0.1 1.3e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CCV00117.1 - 2.5e-06 27.2 0.1 3.9e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 CCV00117.1 - 3.9e-06 26.7 1.2 7.3e-06 25.8 0.1 2.2 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.9 CCV00117.1 - 0.0063 17.1 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Put_Phosphatase PF06888.12 CCV00117.1 - 0.09 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative Phosphatase Ubiquitin_5 PF18037.1 CCV00117.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain GerD PF17898.1 CCV00117.1 - 0.37 10.8 3.5 0.86 9.6 2.5 2.0 2 1 0 2 2 2 0 Spore germination GerD central core domain STI1 PF17830.1 CCV00117.1 - 9.4 6.3 15.5 4 7.4 3.8 3.9 3 1 1 4 4 4 0 STI1 domain Proteasome PF00227.26 CCV00118.1 - 1.9e-20 73.2 0.0 4.2e-20 72.1 0.0 1.6 1 1 0 1 1 1 1 Proteasome subunit Metallophos PF00149.28 CCV00119.1 - 2.3e-36 126.3 0.6 2.3e-35 122.9 0.3 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCV00119.1 - 0.0012 19.2 0.0 0.0066 16.9 0.0 2.2 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DUF1647 PF07801.11 CCV00119.1 - 0.08 12.7 1.1 2 8.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) DUF5427 PF10310.9 CCV00120.1 - 0.00059 18.9 11.5 0.00099 18.2 11.5 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF5427) Spond_N PF06468.13 CCV00120.1 - 0.31 11.1 0.0 0.31 11.1 0.0 2.1 2 1 0 2 2 2 0 Spondin_N Ribosomal_L19e PF01280.20 CCV00121.1 - 3e-62 209.0 10.4 3e-62 209.0 10.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e Methyltransf_31 PF13847.6 CCV00122.1 - 1.4e-11 44.5 0.0 4.3e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCV00122.1 - 2.1e-05 25.2 0.0 4.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CCV00122.1 - 0.00018 21.5 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCV00122.1 - 0.00024 21.7 0.0 0.00046 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_S8 PF00410.19 CCV00122.1 - 0.00062 19.7 0.0 0.0056 16.6 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S8 MDMPI_C PF07398.11 CCV00122.1 - 0.012 16.4 0.1 0.026 15.4 0.1 1.5 1 0 0 1 1 1 0 MDMPI C-terminal domain MTS PF05175.14 CCV00122.1 - 0.042 13.4 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 CCV00122.1 - 0.093 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF768 PF05589.11 CCV00122.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF768) ATP-grasp_2 PF08442.10 CCV00123.1 - 7e-71 238.0 1.0 1e-70 237.4 0.2 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 CCV00123.1 - 3.4e-23 82.2 0.8 8e-23 80.9 0.8 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 CCV00123.1 - 8.4e-13 48.3 0.6 1.9e-12 47.1 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CCV00123.1 - 0.00022 20.8 0.1 0.00053 19.5 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 CCV00123.1 - 0.0026 17.6 0.9 0.0077 16.0 0.2 2.1 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 CCV00123.1 - 0.024 14.2 0.1 0.07 12.7 0.1 1.8 1 1 0 1 1 1 0 ATP-grasp domain Rrp15p PF07890.12 CCV00124.1 - 1.1e-14 54.9 3.8 1.1e-14 54.9 3.8 2.6 1 1 1 2 2 2 1 Rrp15p Roughex PF06020.11 CCV00124.1 - 3.1 6.8 8.4 4.4 6.3 8.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DNA_pol_phi PF04931.13 CCV00124.1 - 5.2 5.0 17.3 1.9 6.5 14.0 1.8 2 0 0 2 2 2 0 DNA polymerase phi BCAS2 PF05700.11 CCV00125.1 - 5.9e-61 205.8 7.0 6.8e-61 205.6 7.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) HR1 PF02185.16 CCV00125.1 - 1.4 9.1 4.8 2.7 8.1 0.0 3.1 3 0 0 3 3 3 0 Hr1 repeat Complex1_30kDa PF00329.19 CCV00126.1 - 4.6e-45 153.2 0.0 6.1e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit SGT1 PF07093.11 CCV00127.1 - 2.7e-64 217.7 2.3 6.7e-64 216.4 2.3 1.6 1 1 0 1 1 1 1 SGT1 protein QLQ PF08880.11 CCV00127.1 - 0.25 11.1 1.3 11 5.8 1.6 2.5 2 0 0 2 2 2 0 QLQ TEX19 PF15553.6 CCV00127.1 - 0.7 9.8 3.0 0.8 9.7 1.4 1.9 1 1 0 1 1 1 0 Testis-expressed protein 19 Peptidase_C48 PF02902.19 CCV00128.1 - 8.3e-34 117.3 0.0 1.5e-33 116.5 0.0 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LCAT PF02450.15 CCV00129.1 - 7.6e-81 272.3 0.0 9.4e-80 268.7 0.0 2.1 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase MMR_HSR1_Xtn PF16897.5 CCV00129.1 - 3.3e-41 139.6 0.5 6.2e-41 138.7 0.5 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CCV00129.1 - 2.7e-18 66.1 0.0 5.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CCV00129.1 - 9.7e-18 64.0 0.1 2e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CCV00129.1 - 2.8e-09 36.7 0.0 5.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Abhydrolase_6 PF12697.7 CCV00129.1 - 0.0034 18.0 0.0 0.015 15.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CCV00129.1 - 0.025 14.3 0.1 0.087 12.5 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_1 PF00561.20 CCV00129.1 - 0.082 12.5 0.2 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Dynamin_N PF00350.23 CCV00129.1 - 0.098 12.7 0.2 6.5 6.8 0.0 2.3 1 1 1 2 2 2 0 Dynamin family AAA_28 PF13521.6 CCV00129.1 - 0.13 12.6 0.5 0.28 11.4 0.5 1.6 1 0 0 1 1 1 0 AAA domain Hydrolase_4 PF12146.8 CCV00129.1 - 0.13 11.5 0.0 0.4 9.9 0.0 1.8 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AAA_16 PF13191.6 CCV00129.1 - 0.14 12.6 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain CBS PF00571.28 CCV00130.1 - 6.3e-07 29.8 0.0 1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 CBS domain Rrn6 PF10214.9 CCV00130.1 - 2 6.8 5.0 2.4 6.6 5.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CBS PF00571.28 CCV00131.1 - 1.5e-19 70.1 2.1 9.9e-08 32.3 0.3 4.1 3 1 0 3 3 3 3 CBS domain PB1 PF00564.24 CCV00131.1 - 0.00092 19.1 0.5 0.0024 17.8 0.5 1.6 1 0 0 1 1 1 1 PB1 domain Acyl-CoA_dh_1 PF00441.24 CCV00132.1 - 9.9e-40 136.2 2.1 1.6e-39 135.5 2.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CCV00132.1 - 6.1e-27 93.7 0.0 1.4e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CCV00132.1 - 6.2e-25 88.1 0.2 1.3e-24 87.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CCV00132.1 - 1.3e-15 57.8 3.0 3.1e-15 56.6 3.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CCV00132.1 - 0.00065 19.5 0.0 0.0022 17.7 0.0 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal SUR7 PF06687.12 CCV00133.1 - 2.5e-16 60.0 3.7 3e-16 59.7 3.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family NADH5_C PF06455.11 CCV00133.1 - 0.012 15.3 0.6 0.012 15.3 0.6 1.5 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus DUF5336 PF17270.2 CCV00133.1 - 0.022 14.4 2.8 0.041 13.5 2.5 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5336) DUF2207 PF09972.9 CCV00133.1 - 0.12 11.1 1.2 0.18 10.5 1.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_U4 PF03419.13 CCV00133.1 - 0.41 9.9 4.9 0.39 10.0 3.7 1.5 1 1 0 1 1 1 0 Sporulation factor SpoIIGA DUF3278 PF11683.8 CCV00133.1 - 0.62 10.2 4.4 0.27 11.3 1.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF4231 PF14015.6 CCV00133.1 - 0.73 10.3 5.6 0.15 12.6 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2614 PF11023.8 CCV00133.1 - 1.7 8.8 4.2 0.45 10.6 1.1 1.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain CorA PF01544.18 CCV00134.1 - 1.5e-44 152.5 0.9 2.7e-44 151.6 0.9 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ACT_4 PF13291.6 CCV00134.1 - 0.11 13.1 0.2 0.36 11.4 0.2 1.9 2 0 0 2 2 2 0 ACT domain A_thal_3526 PF09713.10 CCV00134.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Mannosyl_trans PF05007.13 CCV00135.1 - 1.3e-47 162.9 9.9 5.9e-39 134.5 0.1 2.8 2 1 1 3 3 3 2 Mannosyltransferase (PIG-M) Sugar_tr PF00083.24 CCV00138.1 - 2.9e-100 336.3 10.1 4e-100 335.8 10.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCV00138.1 - 3.2e-10 39.5 12.2 3.2e-10 39.5 12.2 3.5 3 2 1 4 4 4 2 Major Facilitator Superfamily DPBB_1 PF03330.18 CCV00139.1 - 0.0098 16.2 0.0 0.034 14.4 0.0 2.0 1 1 0 1 1 1 1 Lytic transglycolase DUF4551 PF15087.6 CCV00139.1 - 0.38 9.5 21.5 0.45 9.3 21.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hydantoinase_B PF02538.14 CCV00140.1 - 1.8e-216 719.5 0.0 2.1e-216 719.3 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Pkinase PF00069.25 CCV00141.1 - 3.5e-67 226.6 0.0 5.7e-67 225.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCV00141.1 - 8.7e-46 156.3 0.0 1.3e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 CCV00141.1 - 1.5e-14 54.1 0.0 7.6e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 CCV00141.1 - 4.2e-07 29.6 0.0 8.9e-06 25.2 0.0 2.4 2 0 0 2 2 2 1 Kinase-like RA PF00788.23 CCV00141.1 - 0.0019 18.8 0.0 0.0044 17.6 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.14 CCV00141.1 - 0.04 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCV00141.1 - 0.081 12.8 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family E1-E2_ATPase PF00122.20 CCV00142.1 - 3.8e-23 81.9 0.0 9.3e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CCV00142.1 - 3.4e-14 53.6 0.0 1.5e-07 31.9 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCV00142.1 - 0.0007 19.6 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCV00142.1 - 0.016 14.9 0.1 0.049 13.4 0.1 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Mito_carr PF00153.27 CCV00143.1 - 2.4e-53 178.0 0.1 6.5e-19 67.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RIC1 PF07064.13 CCV00144.1 - 2.1e-62 210.8 0.0 3e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 CCV00144.1 - 0.0009 19.5 0.0 0.042 14.1 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 CCV00145.1 - 4.4e-67 226.2 0.0 7.1e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCV00145.1 - 3.7e-35 121.4 0.0 7.7e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCV00145.1 - 8.7e-06 25.3 0.0 4.2e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CCV00145.1 - 0.00044 19.4 0.1 0.00072 18.7 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 CCV00145.1 - 0.0028 16.5 0.0 0.0059 15.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Arylesterase PF01731.20 CCV00146.1 - 0.029 14.5 0.0 0.15 12.3 0.0 2.3 3 0 0 3 3 3 0 Arylesterase Str_synth PF03088.16 CCV00146.1 - 0.25 11.5 0.0 0.47 10.6 0.0 1.3 1 0 0 1 1 1 0 Strictosidine synthase Synaptobrevin PF00957.21 CCV00147.1 - 1.6e-11 43.8 0.8 3.6e-11 42.7 0.8 1.6 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CCV00147.1 - 7.1e-11 42.0 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 CCV00147.1 - 0.081 12.6 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region COPIIcoated_ERV PF07970.12 CCV00147.1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter PHD PF00628.29 CCV00148.1 - 1.7e-10 40.6 23.8 6.8e-06 25.9 0.4 3.5 3 1 0 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.6 CCV00148.1 - 1.9 8.8 5.2 1.7 8.9 1.5 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-PHD-like PF15446.6 CCV00148.1 - 2 8.0 7.2 2.4 7.8 3.0 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DUF2389 PF09493.10 CCV00149.1 - 0.082 13.6 0.0 0.32 11.7 0.0 2.0 1 0 0 1 1 1 0 Tryptophan-rich protein (DUF2389) KxDL PF10241.9 CCV00149.1 - 0.19 12.0 3.1 5.9 7.2 0.9 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein FAM76 PF16046.5 CCV00149.1 - 0.38 10.1 4.4 0.73 9.1 4.4 1.4 1 0 0 1 1 1 0 FAM76 protein APG6_N PF17675.1 CCV00149.1 - 0.47 11.0 15.8 0.91 10.1 1.8 2.6 1 1 0 2 2 2 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 CCV00149.1 - 0.49 11.3 10.2 0.55 11.2 0.6 2.7 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF724 PF05266.14 CCV00149.1 - 0.55 10.0 6.7 0.45 10.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF948 PF06103.11 CCV00149.1 - 0.67 10.2 3.9 9.8 6.5 0.8 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 CCV00149.1 - 0.71 10.3 11.3 1.9 8.9 11.3 1.8 1 1 0 1 1 1 0 Fez1 DivIC PF04977.15 CCV00149.1 - 0.8 9.5 6.9 8.1 6.3 0.4 3.0 3 0 0 3 3 3 0 Septum formation initiator T3SSipB PF16535.5 CCV00149.1 - 2.5 8.5 9.3 2.5 8.6 0.9 2.6 2 1 1 3 3 3 0 Type III cell invasion protein SipB 2-oxoacid_dh PF00198.23 CCV00150.1 - 1.2e-80 270.3 0.1 1.7e-80 269.8 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CCV00150.1 - 1.3e-19 69.8 3.9 3.1e-19 68.6 3.9 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 CCV00150.1 - 0.00092 19.9 0.2 0.48 11.1 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein YL1 PF05764.13 CCV00150.1 - 0.03 14.5 21.1 0.04 14.1 21.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Presenilin PF01080.17 CCV00150.1 - 0.079 11.7 9.1 0.11 11.2 9.1 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CCV00150.1 - 0.23 9.7 13.1 0.27 9.5 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Coilin_N PF15862.5 CCV00150.1 - 0.44 10.4 9.6 0.32 10.8 7.6 1.8 1 1 0 1 1 1 0 Coilin N-terminus RR_TM4-6 PF06459.12 CCV00150.1 - 1.6 8.5 23.6 2.2 8.1 23.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.6 CCV00150.1 - 1.8 7.2 10.0 2.5 6.8 10.0 1.1 1 0 0 1 1 1 0 Raftlin GAGA_bind PF06217.12 CCV00150.1 - 1.9 8.7 10.1 2.7 8.2 10.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Ndc1_Nup PF09531.10 CCV00150.1 - 3.4 6.3 5.7 4.3 5.9 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DNA_pol_phi PF04931.13 CCV00150.1 - 5.2 5.0 11.8 7.1 4.6 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi PTPRCAP PF15713.5 CCV00150.1 - 6.2 7.1 12.8 11 6.3 12.8 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Neur_chan_memb PF02932.16 CCV00150.1 - 6.8 6.7 5.9 8.8 6.3 5.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mito_carr PF00153.27 CCV00151.1 - 1.5e-53 178.7 1.5 2.3e-18 65.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 CCV00152.1 - 1.7e-66 224.3 0.0 2.1e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCV00152.1 - 5.7e-38 130.7 0.0 9.7e-38 129.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCV00152.1 - 5.6e-05 22.1 0.0 8.2e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CCV00152.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CCV00152.1 - 0.0021 17.1 0.1 0.0028 16.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CCV00152.1 - 0.15 11.7 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 RIO1 family SQS_PSY PF00494.19 CCV00153.1 - 1.3e-43 149.4 0.1 2.3e-43 148.6 0.1 1.4 1 1 0 1 1 1 1 Squalene/phytoene synthase ORC2 PF04084.14 CCV00154.1 - 4.8e-41 140.8 0.0 6.3e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Motile_Sperm PF00635.26 CCV00155.1 - 1.3e-25 89.4 0.1 2.5e-25 88.4 0.1 1.5 1 1 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 CCV00155.1 - 0.00021 21.4 0.2 0.00042 20.5 0.2 1.4 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin 4HBT_3 PF13622.6 CCV00156.1 - 6e-33 115.1 5.4 1.7e-32 113.6 5.4 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CCV00156.1 - 0.004 17.0 0.1 0.0096 15.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA thioesterase VirB8 PF04335.13 CCV00156.1 - 0.047 13.5 0.1 0.083 12.7 0.1 1.3 1 0 0 1 1 1 0 VirB8 protein ATP-synt_ab PF00006.25 CCV00157.1 - 1.7e-67 227.2 0.0 2.4e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CCV00157.1 - 3.3e-12 46.8 0.2 6.3e-12 45.8 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 CCV00157.1 - 0.0094 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) HAS-barrel PF09378.10 CCV00157.1 - 0.084 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 HAS barrel domain DUF561 PF04481.12 CCV00157.1 - 0.094 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Ribosomal_L28 PF00830.19 CCV00158.1 - 3.2e-17 62.5 0.2 6.4e-17 61.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal L28 family Brix PF04427.18 CCV00159.1 - 7.5e-31 107.7 0.2 9.9e-31 107.3 0.2 1.2 1 0 0 1 1 1 1 Brix domain DAO PF01266.24 CCV00160.1 - 7e-47 160.7 0.2 9.6e-47 160.2 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CCV00160.1 - 1.2e-40 138.3 0.1 2.8e-40 137.1 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CCV00160.1 - 4.6e-09 35.9 4.3 0.00015 21.0 0.6 2.7 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 CCV00160.1 - 3.2e-05 23.5 2.1 9.1e-05 22.0 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CCV00160.1 - 0.00012 21.4 0.6 0.00068 19.0 0.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCV00160.1 - 0.00015 21.0 0.4 0.012 14.7 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CCV00160.1 - 0.0035 17.5 0.3 0.024 14.9 0.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CCV00160.1 - 0.0048 16.2 0.2 0.015 14.6 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 CCV00160.1 - 0.017 15.0 0.2 0.041 13.8 0.2 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 CCV00160.1 - 0.02 13.6 1.1 0.031 13.0 1.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Sacchrp_dh_NADP PF03435.18 CCV00160.1 - 0.03 14.6 0.0 0.071 13.4 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 CCV00160.1 - 0.033 13.4 0.1 0.092 12.0 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCV00160.1 - 0.037 14.6 0.6 0.087 13.4 0.6 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HHH_4 PF14490.6 CCV00160.1 - 0.098 12.7 0.0 5.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain Rad17 PF03215.15 CCV00161.1 - 4.1e-16 59.4 0.0 9.8e-16 58.2 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CCV00161.1 - 5.3e-09 36.7 0.5 5.3e-09 36.7 0.5 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCV00161.1 - 4.4e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CCV00161.1 - 0.00051 20.3 0.2 0.054 13.7 0.0 2.5 1 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CCV00161.1 - 0.0021 18.6 0.0 0.0038 17.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 CCV00161.1 - 0.04 14.3 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CCV00161.1 - 0.042 13.6 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCV00161.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 CCV00161.1 - 0.064 13.4 0.2 0.21 11.8 0.2 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CCV00161.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CCV00161.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 CCV00161.1 - 0.22 12.1 0.0 0.51 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain IBN_N PF03810.19 CCV00162.1 - 8.2e-14 51.3 0.0 2.7e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 CCV00162.1 - 1e-06 27.8 0.0 2.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.6 CCV00162.1 - 0.0015 18.9 3.5 0.24 11.8 0.2 3.7 3 0 0 3 3 3 2 HEAT repeats Xpo1 PF08389.12 CCV00162.1 - 0.0039 17.3 0.2 0.03 14.4 0.0 2.7 3 0 0 3 3 3 1 Exportin 1-like protein Vac14_Fab1_bd PF12755.7 CCV00162.1 - 0.042 14.5 0.1 1.4 9.6 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CCV00162.1 - 4.6 7.8 12.7 6.3 7.3 0.0 6.0 8 0 0 8 8 8 0 HEAT repeat Sdh5 PF03937.16 CCV00163.1 - 1.6e-26 92.1 0.5 2.2e-26 91.6 0.5 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Ribosomal_L37ae PF01780.19 CCV00164.1 - 6.1e-39 132.0 6.8 8.3e-39 131.6 6.8 1.2 1 0 0 1 1 1 1 Ribosomal L37ae protein family DUF1364 PF07102.12 CCV00164.1 - 0.011 15.6 0.2 0.019 14.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Zn_Tnp_IS1595 PF12760.7 CCV00164.1 - 0.018 15.0 2.7 0.032 14.2 2.7 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 CCV00164.1 - 0.033 13.6 1.7 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_13 PF17977.1 CCV00164.1 - 0.037 14.2 1.7 0.051 13.7 1.7 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.6 CCV00164.1 - 0.081 13.4 4.8 0.48 10.9 0.7 2.3 1 1 1 2 2 2 0 Zinc-finger double domain C1_2 PF03107.16 CCV00164.1 - 0.11 12.9 3.7 0.95 9.8 3.9 2.0 1 1 0 1 1 1 0 C1 domain Elf1 PF05129.13 CCV00164.1 - 0.11 12.5 2.1 0.18 11.9 1.9 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like NOB1_Zn_bind PF08772.11 CCV00164.1 - 0.23 11.7 3.4 1 9.5 0.2 2.7 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-C4_ClpX PF06689.13 CCV00164.1 - 0.3 11.0 2.5 0.38 10.7 0.2 2.1 2 0 0 2 2 2 0 ClpX C4-type zinc finger YyzF PF14116.6 CCV00164.1 - 0.53 10.3 0.1 0.53 10.3 0.1 1.7 2 0 0 2 2 2 0 YyzF-like protein DnaJ PF00226.31 CCV00165.1 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CCV00165.1 - 0.0021 18.1 0.0 0.0024 17.9 0.0 1.1 1 0 0 1 1 1 1 Pam16 WD40 PF00400.32 CCV00166.1 - 6e-13 49.1 13.3 0.00062 20.5 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 CCV00166.1 - 0.058 12.0 3.3 5.7 5.4 0.0 3.4 4 1 0 5 5 5 0 Nucleoporin Nup120/160 Sec23_trunk PF04811.15 CCV00167.1 - 9.6e-74 248.0 0.0 1.3e-73 247.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CCV00167.1 - 1.3e-30 105.9 0.1 2.5e-30 105.1 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CCV00167.1 - 1.5e-26 92.2 0.2 3.1e-26 91.2 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CCV00167.1 - 6e-16 58.2 6.5 1.4e-15 57.1 6.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CCV00167.1 - 2.5e-12 46.5 0.0 5.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CCV00167.1 - 0.043 13.2 0.1 0.093 12.1 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain UL42 PF17638.2 CCV00167.1 - 3.1 7.8 8.0 0.47 10.4 2.3 2.3 3 0 0 3 3 3 0 HCMV UL42 IML1 PF12257.8 CCV00168.1 - 3.7e-107 357.7 0.0 5.1e-107 357.2 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 CCV00168.1 - 2e-17 63.0 0.3 5.6e-17 61.6 0.3 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PAP2_3 PF14378.6 CCV00169.1 - 7.2e-22 78.0 16.5 7.2e-22 78.0 16.5 2.2 1 1 2 3 3 3 1 PAP2 superfamily PAP2 PF01569.21 CCV00169.1 - 8.5e-11 41.8 5.0 8.5e-11 41.8 5.0 2.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CCV00169.1 - 8.4 7.0 12.1 0.12 12.9 3.4 2.4 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Peptidase_S26 PF10502.9 CCV00170.1 - 5.9e-08 32.6 0.0 9.5e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 CCV00170.1 - 2.7e-05 24.1 0.0 6.9e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like Mito_carr PF00153.27 CCV00171.1 - 1.1e-34 118.3 0.3 1.9e-17 63.0 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein IF4E PF01652.18 CCV00172.1 - 1.6e-32 112.5 0.0 3.4e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Fer2_3 PF13085.6 CCV00173.1 - 1.1e-33 115.5 0.0 1.8e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CCV00173.1 - 3.8e-09 37.0 5.9 3.8e-09 37.0 5.9 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CCV00173.1 - 5.6e-07 29.9 7.2 5.6e-07 29.9 7.2 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CCV00173.1 - 1.1e-06 28.7 3.7 1.1e-06 28.7 3.7 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CCV00173.1 - 0.0017 18.2 0.4 0.0017 18.2 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CCV00173.1 - 0.013 16.1 6.1 0.013 16.1 6.1 2.5 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 CCV00173.1 - 0.14 12.4 10.8 0.36 11.0 8.3 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain BIR PF00653.21 CCV00175.1 - 4.1e-18 65.8 2.4 1.1e-17 64.4 2.4 1.8 1 1 0 1 1 1 1 Inhibitor of Apoptosis domain Sec10 PF07393.11 CCV00176.1 - 2.7e-84 283.9 0.0 7.2e-84 282.6 0.0 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec10 F-box PF00646.33 CCV00176.1 - 0.00019 21.2 0.1 0.00019 21.2 0.1 2.9 3 0 0 3 3 3 1 F-box domain SOTI PF17079.5 CCV00176.1 - 0.055 13.9 0.3 0.26 11.7 0.1 2.2 2 0 0 2 2 2 0 Male-specific protein scotti F-box-like PF12937.7 CCV00176.1 - 0.52 10.3 6.4 0.12 12.3 0.4 2.8 3 0 0 3 3 3 0 F-box-like SBF PF01758.16 CCV00177.1 - 2.3e-49 167.7 12.8 2.3e-49 167.7 12.8 1.6 2 0 0 2 2 2 1 Sodium Bile acid symporter family PalH PF08733.10 CCV00177.1 - 3.1 6.7 10.9 4.9 6.0 10.9 1.2 1 0 0 1 1 1 0 PalH/RIM21 Ras PF00071.22 CCV00178.1 - 1.1e-40 138.8 0.0 1.6e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCV00178.1 - 8.4e-25 87.3 0.0 1.5e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCV00178.1 - 2.1e-06 27.3 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCV00178.1 - 0.00052 20.1 0.0 0.0014 18.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Sigma54_activat PF00158.26 CCV00178.1 - 0.0054 16.4 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 CCV00178.1 - 0.0065 16.9 0.2 0.014 15.8 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCV00178.1 - 0.0075 16.6 0.0 0.015 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 CCV00178.1 - 0.012 15.0 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 CCV00178.1 - 0.02 14.8 0.1 0.058 13.3 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 CCV00178.1 - 0.048 13.7 0.1 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CCV00178.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CCV00178.1 - 0.065 13.0 0.0 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein TniB PF05621.11 CCV00178.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 CCV00178.1 - 0.067 12.9 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CCV00178.1 - 0.071 12.6 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CCV00178.1 - 0.086 13.2 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 CCV00178.1 - 0.12 12.5 0.2 0.19 11.9 0.2 1.5 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 CCV00178.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 CCV00178.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CCV00178.1 - 0.19 12.3 0.0 0.32 11.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CCV00178.1 - 0.19 11.6 0.0 0.61 10.0 0.0 1.7 2 1 1 3 3 3 0 RsgA GTPase WD40 PF00400.32 CCV00179.1 - 3.6e-33 113.0 13.1 6.9e-09 36.2 0.2 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCV00179.1 - 1.9e-12 47.3 0.0 9.8e-05 22.6 0.0 4.9 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCV00179.1 - 4.7e-05 22.5 0.0 0.13 11.2 0.0 3.2 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CCV00179.1 - 0.0046 16.3 0.0 5.1 6.3 0.0 2.8 2 1 1 3 3 3 2 WD40-like domain PD40 PF07676.12 CCV00179.1 - 0.062 13.3 0.0 4.7 7.3 0.0 3.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WDCP PF15390.6 CCV00179.1 - 0.14 10.5 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Peptidase_C25_C PF03785.14 CCV00179.1 - 0.19 11.6 0.9 0.84 9.5 0.2 2.2 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain Rib_5-P_isom_A PF06026.14 CCV00180.1 - 1.4e-51 174.5 0.0 2.1e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CCV00180.1 - 0.056 13.4 0.9 0.21 11.5 0.9 1.9 1 1 0 1 1 1 0 DeoR C terminal sensor domain Rubi_NSP_C PF12601.8 CCV00180.1 - 0.19 11.9 1.0 15 5.8 0.3 2.6 1 1 1 2 2 2 0 Rubivirus non-structural protein Bmt2 PF11968.8 CCV00181.1 - 1.8e-56 191.5 0.0 2.3e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 CCV00181.1 - 1.4e-07 31.5 0.0 2.7e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CCV00181.1 - 4.2e-07 30.0 0.0 5.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CCV00181.1 - 0.00068 20.2 0.1 0.0022 18.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCV00181.1 - 0.046 14.5 0.1 0.11 13.2 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Glutaredoxin PF00462.24 CCV00182.1 - 6.4e-18 64.7 0.0 1e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 CCV00182.1 - 0.00024 21.5 0.1 0.00053 20.4 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 CCV00182.1 - 0.011 16.2 0.0 0.017 15.6 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 CCV00182.1 - 0.013 15.9 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 CCV00182.1 - 0.053 13.6 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain TraF PF13728.6 CCV00182.1 - 0.063 13.1 0.0 0.073 12.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF953 PF06110.11 CCV00182.1 - 0.12 12.0 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.6 CCV00182.1 - 0.14 12.3 0.1 0.2 11.9 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like DSBA PF01323.20 CCV00182.1 - 0.23 11.2 0.4 0.66 9.7 0.2 1.7 1 1 0 2 2 2 0 DSBA-like thioredoxin domain WD40 PF00400.32 CCV00183.1 - 9.1e-29 99.1 13.3 0.00061 20.6 0.1 8.8 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCV00183.1 - 1.2e-05 25.5 0.0 2.9 8.2 0.0 5.1 3 3 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain EST1_DNA_bind PF10373.9 CCV00184.1 - 7.6e-26 91.2 0.0 1.6e-23 83.6 0.0 3.2 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CCV00184.1 - 1.2e-18 68.1 0.0 2.3e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Telomerase activating protein Est1 DUF3209 PF11483.8 CCV00184.1 - 0.055 13.9 0.4 1.1 9.7 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) RPN7 PF10602.9 CCV00185.1 - 8.5e-12 45.1 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_2 PF07719.17 CCV00185.1 - 0.0056 16.7 3.5 0.0075 16.3 1.6 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCV00185.1 - 0.017 15.0 0.5 0.047 13.5 0.5 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCV00185.1 - 0.028 14.7 2.2 0.028 14.7 2.2 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCV00185.1 - 0.084 12.9 0.7 0.084 12.9 0.7 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CCV00185.1 - 0.1 13.5 1.4 0.1 13.5 1.4 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat RWD PF05773.22 CCV00186.1 - 1.5e-17 64.0 0.1 2.9e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 CCV00186.1 - 0.00062 20.2 14.0 0.00075 19.9 10.5 2.9 2 1 1 3 3 3 1 DRG Family Regulatory Proteins, Tma46 OmpH PF03938.14 CCV00186.1 - 1.7 9.0 9.1 3.8 7.9 9.1 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HSP70 PF00012.20 CCV00187.1 - 1.9e-253 842.1 13.1 2.2e-253 841.9 13.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCV00187.1 - 1.5e-15 56.8 4.4 1.4e-13 50.3 2.5 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CCV00187.1 - 0.0026 18.2 9.9 0.14 12.6 0.7 4.2 3 1 0 3 3 3 2 Cell division protein FtsA SRP_SPB PF02978.19 CCV00187.1 - 0.092 13.4 0.0 0.39 11.4 0.0 2.1 1 0 0 1 1 1 0 Signal peptide binding domain Seryl_tRNA_N PF02403.22 CCV00187.1 - 0.7 10.1 9.5 1.9 8.8 9.5 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3818 PF12825.7 CCV00188.1 - 1.4e-108 363.0 1.6 2e-108 362.4 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PX PF00787.24 CCV00188.1 - 1.9e-15 56.8 0.2 1.1e-14 54.4 0.0 2.3 2 0 0 2 2 2 1 PX domain PXB PF12828.7 CCV00188.1 - 1.4e-09 38.0 0.4 4e-09 36.6 0.1 2.0 2 0 0 2 2 2 1 PX-associated YxiJ PF14176.6 CCV00188.1 - 0.1 13.1 0.0 0.32 11.5 0.0 1.9 1 0 0 1 1 1 0 YxiJ-like protein MAS20 PF02064.15 CCV00189.1 - 7.4e-40 136.0 2.5 7.4e-40 136.0 2.5 2.8 2 1 0 2 2 2 1 MAS20 protein import receptor PMC2NT PF08066.12 CCV00189.1 - 0.023 15.4 1.5 0.043 14.5 0.0 2.2 2 1 0 2 2 2 0 PMC2NT (NUC016) domain Nucleolin_bd PF16725.5 CCV00189.1 - 0.15 11.7 1.3 0.34 10.6 1.3 1.6 1 0 0 1 1 1 0 Nucleolin binding domain SAPS PF04499.15 CCV00189.1 - 0.8 8.4 6.7 1 8.1 6.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Lin-8 PF03353.15 CCV00189.1 - 2.3 7.7 19.4 10 5.6 0.1 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Mitofilin PF09731.9 CCV00189.1 - 6.3 5.5 26.7 14 4.4 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Choline_kinase PF01633.20 CCV00190.1 - 1.2e-33 116.5 0.0 1.1e-21 77.4 0.0 3.1 2 1 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 CCV00190.1 - 3.3e-07 30.5 0.0 0.023 14.6 0.0 3.2 3 0 0 3 3 3 2 Phosphotransferase enzyme family XPG_I_2 PF12813.7 CCV00191.1 - 9.3e-05 22.0 0.1 0.00027 20.5 0.1 1.8 1 1 0 1 1 1 1 XPG domain containing PTPRCAP PF15713.5 CCV00191.1 - 0.085 13.1 10.5 0.17 12.1 10.5 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 CCV00191.1 - 0.092 11.0 1.7 0.12 10.7 1.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 CCV00191.1 - 1.6 7.5 5.6 2.7 6.7 5.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FHA PF00498.26 CCV00192.1 - 2.9e-15 56.4 0.0 4.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CCV00192.1 - 0.00024 21.3 0.0 0.16 12.3 0.0 2.9 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RNA_lig_T4_1 PF09511.10 CCV00193.1 - 1.9e-81 273.1 0.0 6.9e-81 271.3 0.0 1.8 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.11 CCV00193.1 - 9.1e-12 45.4 0.0 1.6e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain Cu-oxidase_3 PF07732.15 CCV00194.1 - 2.3e-32 111.5 4.9 1e-21 77.1 0.3 3.5 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 CCV00194.1 - 1.1e-27 97.1 0.0 5.1e-27 94.9 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CCV00194.1 - 5.1e-19 68.4 1.3 5.1e-19 68.4 1.3 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CCV00195.1 - 4.7e-32 110.6 5.0 4.7e-32 110.6 5.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 CCV00195.1 - 1.5e-30 106.4 0.0 7.7e-29 100.9 0.0 2.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CCV00195.1 - 2e-19 69.8 3.6 2.1e-19 69.7 0.1 2.9 4 1 0 4 4 4 1 Multicopper oxidase Phosphoesterase PF04185.14 CCV00196.1 - 5.5e-74 249.5 2.0 7.9e-74 249.0 2.0 1.2 1 0 0 1 1 1 1 Phosphoesterase family Phosphoesterase PF04185.14 CCV00197.1 - 6.2e-76 255.9 3.7 9e-76 255.4 3.7 1.2 1 0 0 1 1 1 1 Phosphoesterase family NMT1 PF09084.11 CCV00198.1 - 2.6e-75 253.1 0.0 3.2e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 CCV00198.1 - 2.1e-05 24.4 0.1 0.014 15.1 0.0 3.2 2 1 0 2 2 2 2 NMT1-like family NMT1_3 PF16868.5 CCV00198.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 CCV00198.1 - 0.017 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 CCV00198.1 - 0.045 13.2 0.0 0.094 12.1 0.0 1.5 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 PBP_like PF12727.7 CCV00198.1 - 0.06 12.5 0.0 0.56 9.3 0.0 2.1 2 0 0 2 2 2 0 PBP superfamily domain GRDP-like PF07173.12 CCV00199.1 - 6.3e-14 52.8 1.1 9.1e-13 49.1 0.0 2.3 1 1 1 2 2 2 1 Glycine-rich domain-containing protein-like Acetyltransf_2 PF00797.17 CCV00200.1 - 2.1e-27 96.5 0.0 2.5e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase Glyco_hydro_4 PF02056.16 CCV00200.1 - 0.093 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase Catalase PF00199.19 CCV00201.1 - 1.3e-172 574.2 0.0 1.7e-172 573.9 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CCV00201.1 - 4.8e-23 81.1 0.0 1e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 CCV00201.1 - 1.6e-13 50.5 0.3 1.6e-13 50.5 0.3 1.8 2 0 0 2 2 2 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 CCV00201.1 - 0.0026 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Transp_cyt_pur PF02133.15 CCV00202.1 - 7.7e-34 117.2 26.1 1.2e-33 116.6 26.1 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidohydro_3 PF07969.11 CCV00202.1 - 2.2e-31 109.9 0.2 5e-30 105.4 0.2 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CCV00202.1 - 4.7e-10 39.3 0.0 8.3e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family TauD PF02668.16 CCV00203.1 - 2.7e-51 174.9 1.5 3.1e-51 174.8 1.5 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Transp_cyt_pur PF02133.15 CCV00204.1 - 1e-117 393.6 40.0 1.2e-117 393.4 40.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Allantoicase PF03561.15 CCV00205.1 - 4.1e-43 146.8 0.0 5e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Allantoicase repeat DUF5000 PF16391.5 CCV00205.1 - 0.025 14.7 0.1 0.074 13.2 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function Polysacc_deac_1 PF01522.21 CCV00206.1 - 5e-15 55.5 0.0 9.7e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Cu-oxidase_2 PF07731.14 CCV00207.1 - 6.3e-41 139.3 8.7 6.9e-39 132.7 0.6 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CCV00207.1 - 1.5e-35 122.7 0.1 7.9e-35 120.3 0.2 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CCV00207.1 - 4.7e-25 87.9 9.6 1.3e-23 83.3 0.3 4.6 3 1 1 5 5 5 2 Multicopper oxidase Cupredoxin_1 PF13473.6 CCV00207.1 - 0.00014 21.9 0.0 5.9 7.0 0.0 3.7 3 0 0 3 3 3 2 Cupredoxin-like domain Peptidase_M30 PF10460.9 CCV00207.1 - 0.03 13.3 0.0 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase M30 Polysacc_deac_1 PF01522.21 CCV00208.1 - 2.1e-27 95.4 0.0 4e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase HTH_psq PF05225.16 CCV00208.1 - 0.11 12.2 0.1 0.4 10.4 0.1 1.9 1 0 0 1 1 1 0 helix-turn-helix, Psq domain NPR3 PF03666.13 CCV00208.1 - 1.8 7.2 9.6 3.8 6.2 9.6 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tmemb_cc2 PF10267.9 CCV00208.1 - 2.2 7.3 7.0 3.8 6.5 7.0 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Polysacc_deac_1 PF01522.21 CCV00209.1 - 6.5e-18 64.8 0.0 1.2e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase tRNA_int_endo_N PF02778.14 CCV00211.1 - 1.4e-06 27.9 0.0 0.00013 21.6 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Kei1 PF08552.11 CCV00212.1 - 6.8e-53 179.4 2.8 1.2e-52 178.6 2.8 1.4 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 dsDNA_bind PF01984.20 CCV00212.1 - 2.2e-30 105.2 6.6 3.8e-30 104.4 6.6 1.4 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Ran_BP1 PF00638.18 CCV00213.1 - 1.5e-08 34.9 0.0 2.5e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain BCMA-Tall_bind PF09257.10 CCV00213.1 - 0.05 13.7 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 BCMA, TALL-1 binding W2 PF02020.18 CCV00214.1 - 1.8e-14 53.6 0.2 4.9e-14 52.2 0.2 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 CCV00214.1 - 3.6e-11 42.3 6.3 2.7e-05 23.7 0.3 3.5 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 CCV00214.1 - 0.00053 19.6 0.0 0.0012 18.5 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 CCV00214.1 - 0.0012 18.5 4.5 0.18 11.6 0.1 2.6 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CCV00214.1 - 0.003 16.6 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 CCV00214.1 - 0.011 16.1 0.0 0.035 14.4 0.0 2.0 1 0 0 1 1 1 0 MobA-like NTP transferase domain Flavoprotein PF02441.19 CCV00215.1 - 3.3e-29 101.7 0.1 4e-29 101.4 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein Aldo_ket_red PF00248.21 CCV00216.1 - 4.9e-28 98.2 0.0 7e-28 97.7 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family PGK PF00162.19 CCV00217.1 - 1e-151 505.2 1.5 1.1e-151 505.1 1.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.11 CCV00217.1 - 0.34 10.5 1.5 7.1 6.2 0.0 2.8 3 0 0 3 3 3 0 Propionate catabolism activator Pyr_redox PF00070.27 CCV00217.1 - 2.2 8.9 4.8 33 5.1 0.1 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase A_deaminase PF00962.22 CCV00218.1 - 2.6e-119 398.4 0.0 4e-119 397.8 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase DASH_Spc34 PF08657.10 CCV00219.1 - 1.6e-07 31.4 0.7 0.015 15.1 0.0 2.2 1 1 1 2 2 2 2 DASH complex subunit Spc34 Phos_pyr_kin PF08543.12 CCV00220.1 - 3.1e-09 36.6 0.0 5.1e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CCV00220.1 - 1.2e-06 28.1 0.1 2.6e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 pfkB family carbohydrate kinase DNA_pol_B PF00136.21 CCV00221.1 - 2.6e-113 379.2 0.0 1.2e-112 377.0 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 CCV00221.1 - 6e-51 172.8 0.9 1e-50 172.1 0.9 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.8 CCV00221.1 - 7.8e-23 80.3 1.2 2.5e-22 78.7 1.2 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_exo1 PF03104.19 CCV00221.1 - 5.5e-20 71.8 0.0 9.4e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 CCV00221.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral VWA_N2 PF16164.5 CCV00221.1 - 0.15 12.2 1.9 0.4 10.9 0.3 2.4 1 1 1 2 2 2 0 VWA N-terminal Ribosomal_L35Ae PF01247.18 CCV00222.1 - 1.7e-40 137.1 0.2 2.1e-40 136.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CCV00222.1 - 0.011 15.9 0.0 1.6 9.0 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain zf-C2H2_jaz PF12171.8 CCV00223.1 - 9.4e-10 38.5 1.5 1.6e-09 37.8 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCV00223.1 - 0.001 19.4 0.6 0.0017 18.7 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CCV00223.1 - 0.0072 16.7 1.2 0.017 15.6 1.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CCV00223.1 - 0.012 16.0 0.5 0.018 15.4 0.5 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DAO PF01266.24 CCV00224.1 - 9.5e-18 64.9 0.0 1e-09 38.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CCV00224.1 - 6.9e-05 22.1 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CCV00224.1 - 0.0018 18.5 0.1 0.0047 17.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CCV00224.1 - 0.0023 17.2 0.0 0.051 12.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCV00224.1 - 0.0058 17.2 0.2 0.018 15.6 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 CCV00224.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ApbA PF02558.16 CCV00224.1 - 0.025 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 CCV00224.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Ccdc124 PF06244.12 CCV00225.1 - 4.7e-27 95.1 10.8 4.7e-27 95.1 10.8 2.2 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF3835 PF12927.7 CCV00226.1 - 4.5e-05 24.2 0.0 4.5e-05 24.2 0.0 3.3 5 0 0 5 5 5 1 Domain of unknown function (DUF3835) Ribosomal_L27 PF01016.19 CCV00227.1 - 5.8e-32 109.5 0.8 3.2e-31 107.2 0.7 1.9 2 0 0 2 2 2 1 Ribosomal L27 protein Tim17 PF02466.19 CCV00228.1 - 1.8e-22 79.8 4.3 2.4e-22 79.4 4.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family BTB PF00651.31 CCV00229.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain DUF1712 PF08217.11 CCV00230.1 - 0.0052 15.3 0.0 0.0068 14.9 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) POTRA_3 PF17287.2 CCV00230.1 - 0.094 12.2 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 POTRA domain PDH PF02153.17 CCV00232.1 - 3.5e-15 55.7 0.0 5.4e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 CCV00232.1 - 1e-06 29.2 0.0 5.1e-06 27.0 0.0 2.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CCV00232.1 - 1.9e-06 28.1 0.0 3.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 CCV00232.1 - 0.00018 21.2 0.1 0.00052 19.7 0.0 1.8 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 CCV00232.1 - 0.00021 21.2 0.2 0.00043 20.1 0.2 1.5 1 0 0 1 1 1 1 Rossmann-like domain 2-Hacid_dh_C PF02826.19 CCV00232.1 - 0.00081 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CCV00232.1 - 0.0019 18.3 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 CCV00232.1 - 0.019 14.5 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CCV00232.1 - 0.052 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 CCV00232.1 - 0.12 13.2 0.1 0.53 11.1 0.1 2.3 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 CCV00232.1 - 0.15 12.0 0.1 0.43 10.4 0.1 1.8 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Alg14 PF08660.11 CCV00233.1 - 4.1e-50 170.1 0.0 4.8e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Syntaxin PF00804.25 CCV00234.1 - 3.3e-27 95.5 9.0 3.3e-27 95.5 9.0 1.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 CCV00234.1 - 1.5e-08 34.5 2.0 1.5e-08 34.5 2.0 2.2 2 0 0 2 2 2 1 SNARE domain Prominin PF05478.11 CCV00234.1 - 0.00065 17.8 3.1 0.0015 16.6 0.4 2.0 2 0 0 2 2 2 1 Prominin PBP1_TM PF14812.6 CCV00234.1 - 0.0025 18.2 0.1 0.0059 16.9 0.1 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal PBP_N PF17093.5 CCV00234.1 - 0.013 15.8 5.5 0.17 12.1 0.2 2.3 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Syntaxin_2 PF14523.6 CCV00234.1 - 0.016 15.6 6.6 0.02 15.2 0.6 2.7 2 1 0 2 2 2 0 Syntaxin-like protein DUF4658 PF15555.6 CCV00234.1 - 0.018 15.2 1.1 2.1 8.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) DUF3611 PF12263.8 CCV00234.1 - 0.018 15.0 0.2 0.029 14.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Synaptobrevin PF00957.21 CCV00234.1 - 0.019 14.8 3.1 0.019 14.8 3.1 2.0 2 0 0 2 2 2 0 Synaptobrevin Nsp1_C PF05064.13 CCV00234.1 - 0.022 14.6 0.0 0.022 14.6 0.0 2.8 3 0 0 3 3 3 0 Nsp1-like C-terminal region DUF2207 PF09972.9 CCV00234.1 - 0.027 13.3 0.0 0.05 12.4 0.0 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) IL11 PF07400.11 CCV00234.1 - 0.036 13.7 0.3 0.087 12.5 0.0 1.7 2 0 0 2 2 2 0 Interleukin 11 Allexi_40kDa PF05549.11 CCV00234.1 - 0.04 13.4 3.8 0.066 12.7 0.1 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein V_ATPase_I PF01496.19 CCV00234.1 - 0.043 11.7 5.2 0.046 11.6 1.8 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF5345 PF17280.2 CCV00234.1 - 0.062 13.3 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5345) V-SNARE PF05008.15 CCV00234.1 - 0.17 12.3 12.6 0.94 9.9 1.6 4.0 2 1 2 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Laminin_II PF06009.12 CCV00234.1 - 0.22 11.5 5.9 1.4 8.9 1.9 2.5 2 0 0 2 2 2 0 Laminin Domain II SKA1 PF07160.12 CCV00234.1 - 0.31 10.9 7.9 0.33 10.8 1.6 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Baculo_PEP_C PF04513.12 CCV00234.1 - 0.39 10.7 8.3 0.55 10.3 0.6 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF745 PF05335.13 CCV00234.1 - 1.8 8.2 15.2 0.041 13.6 5.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Shisa PF13908.6 CCV00234.1 - 2.5 8.3 4.7 0.64 10.2 0.1 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator LMBR1 PF04791.16 CCV00234.1 - 5.5 5.8 6.1 8.2 5.2 6.1 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein MCU PF04678.13 CCV00234.1 - 6.1 6.9 6.9 1.2 9.3 2.2 1.9 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Ribosomal_L27A PF00828.19 CCV00235.1 - 2e-37 128.7 0.0 2.6e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A MerR_1 PF13411.6 CCV00235.1 - 0.025 14.7 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein DEAD PF00270.29 CCV00236.1 - 6.2e-46 156.4 0.1 3.3e-45 154.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCV00236.1 - 8.9e-26 90.4 0.0 6.5e-25 87.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCV00236.1 - 1.4e-05 25.1 0.3 3.6e-05 23.8 0.0 1.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCV00236.1 - 0.27 11.5 1.4 6.4 7.0 0.7 3.0 2 1 0 2 2 2 0 AAA domain ACC_central PF08326.12 CCV00237.1 - 1.1e-182 609.0 0.0 1.5e-182 608.6 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 CCV00237.1 - 5.7e-156 520.0 0.0 7.5e-156 519.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CCV00237.1 - 2.7e-49 167.5 0.0 5.1e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CCV00237.1 - 8.2e-27 93.9 0.0 2.3e-26 92.5 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CCV00237.1 - 4.9e-19 68.4 0.0 1.1e-17 64.1 0.0 2.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CCV00237.1 - 9.3e-12 44.6 0.0 2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CCV00237.1 - 7.6e-05 22.5 0.0 0.00023 20.9 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like Cytochrom_C1 PF02167.15 CCV00238.1 - 2.1e-95 318.6 0.0 2.6e-95 318.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CCV00238.1 - 0.0043 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Ribosomal_S19 PF00203.21 CCV00239.1 - 2e-29 101.3 0.3 3.4e-29 100.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 ERCC4 PF02732.15 CCV00239.1 - 1.7e-18 67.3 0.0 3e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain FliH PF02108.16 CCV00239.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Flagellar assembly protein FliH HHH_8 PF14716.6 CCV00239.1 - 0.044 14.2 0.1 0.13 12.7 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ribosomal_60s PF00428.19 CCV00240.1 - 4.9e-26 91.1 12.4 5.8e-26 90.9 12.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein RhoGAP PF00620.27 CCV00241.1 - 2.9e-49 166.8 0.7 6.3e-49 165.7 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 CCV00241.1 - 2.6e-08 34.0 2.0 3e-08 33.8 0.3 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4973 PF16343.5 CCV00241.1 - 0.11 12.6 0.1 9.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4973) CAP59_mtransfer PF11735.8 CCV00242.1 - 7.6e-68 228.8 0.0 2.3e-67 227.2 0.0 1.7 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 Mg_trans_NIPA PF05653.14 CCV00243.1 - 2.4e-73 246.8 17.7 3e-73 246.5 17.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CCV00243.1 - 0.00012 22.2 4.0 0.00012 22.2 4.0 2.5 2 1 0 2 2 2 1 EamA-like transporter family PPP4R2 PF09184.11 CCV00244.1 - 6.1e-10 39.2 0.0 6.9e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 PPP4R2 SSF PF00474.17 CCV00245.1 - 4.6e-08 32.3 18.6 5.9e-07 28.7 18.6 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family Spore_permease PF03845.13 CCV00245.1 - 9.5 4.9 23.2 0.016 14.1 9.5 2.2 2 0 0 2 2 2 0 Spore germination protein Ada3 PF10198.9 CCV00246.1 - 2.6e-23 82.6 1.0 6.2e-23 81.4 1.0 1.6 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 ELO PF01151.18 CCV00247.1 - 2.1e-98 328.8 45.1 1.2e-54 185.5 19.8 2.0 2 0 0 2 2 2 2 GNS1/SUR4 family UQ_con PF00179.26 CCV00248.1 - 6.1e-33 113.4 0.2 7.7e-32 109.9 0.2 2.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CCV00248.1 - 0.003 17.8 0.0 0.0034 17.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CCV00248.1 - 0.18 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Myb_DNA-binding PF00249.31 CCV00249.1 - 1.8e-11 44.1 0.0 3.4e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCV00249.1 - 1.1e-05 25.6 0.4 0.14 12.5 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CCV00249.1 - 5.4e-05 23.0 0.3 0.00037 20.3 0.1 2.3 2 0 0 2 2 2 1 Myb DNA-binding like DUF4890 PF16231.5 CCV00249.1 - 5.9 7.4 7.7 0.38 11.3 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) Oxidored_FMN PF00724.20 CCV00250.1 - 3.1e-42 145.1 0.0 7.2e-38 130.7 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family ORC5_C PF14630.6 CCV00251.1 - 1.2e-54 185.8 0.0 1.5e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_22 PF13401.6 CCV00251.1 - 0.094 13.0 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Torus PF16131.5 CCV00252.1 - 1.1e-21 77.5 2.6 1.3e-21 77.3 0.0 2.3 2 1 1 3 3 3 1 Torus domain RRM_1 PF00076.22 CCV00252.1 - 0.013 15.3 0.1 0.043 13.6 0.1 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2-Hacid_dh PF00389.30 CCV00253.1 - 1e-21 77.0 0.0 1e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 CCV00253.1 - 1.7e-09 37.3 0.0 3.7e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CCV00253.1 - 0.15 12.7 0.0 0.69 10.5 0.0 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_M16 PF00675.20 CCV00254.1 - 6.2e-19 68.4 0.0 1.2e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCV00254.1 - 1.9e-14 54.1 0.0 3.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Kin17_mid PF10357.9 CCV00255.1 - 2.1e-46 156.9 0.1 3.3e-46 156.3 0.1 1.2 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein betaPIX_CC PF16523.5 CCV00255.1 - 0.0011 18.8 2.0 0.0031 17.3 1.3 1.9 2 0 0 2 2 2 1 betaPIX coiled coil PIN_8 PF18476.1 CCV00255.1 - 0.38 10.6 2.7 1.2 8.9 2.7 1.8 1 1 0 1 1 1 0 PIN like domain SHMT PF00464.19 CCV00256.1 - 2.3e-171 569.8 0.0 2.6e-171 569.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CCV00256.1 - 6.6e-08 32.2 0.0 5.3e-07 29.2 0.0 2.1 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CCV00256.1 - 0.0021 17.3 0.0 0.0053 16.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Macro PF01661.21 CCV00256.1 - 0.026 14.6 0.1 0.084 12.9 0.0 1.8 2 0 0 2 2 2 0 Macro domain DUF4142 PF13628.6 CCV00256.1 - 0.32 11.2 0.2 0.32 11.2 0.2 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4142) Asp_protease PF09668.10 CCV00257.1 - 8.1e-58 193.6 0.0 1.4e-57 192.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CCV00257.1 - 8.9e-22 77.5 0.0 1.7e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 CCV00257.1 - 1.9e-10 40.3 0.0 3.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.6 CCV00257.1 - 2.1e-10 41.1 0.0 4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CCV00257.1 - 5.7e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CCV00257.1 - 0.00011 22.4 0.0 0.00046 20.5 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 CCV00257.1 - 0.00062 19.5 0.1 0.0026 17.6 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 CCV00257.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain YukD PF08817.10 CCV00257.1 - 0.026 15.2 0.1 0.06 14.1 0.1 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD OB_NTP_bind PF07717.16 CCV00258.1 - 1.4e-15 57.4 0.0 2.9e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CCV00258.1 - 3.4e-15 56.3 0.7 1.1e-14 54.6 0.0 2.3 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCV00258.1 - 2.4e-12 47.2 0.0 5.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 CCV00258.1 - 0.00022 21.0 0.1 0.00054 19.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CCV00258.1 - 0.0009 19.1 0.4 1.6 8.5 0.1 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.6 CCV00258.1 - 0.00097 19.4 0.7 0.011 16.1 0.7 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CCV00258.1 - 0.0013 18.8 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CCV00258.1 - 0.0036 17.8 0.0 0.013 16.0 0.0 2.0 2 0 0 2 2 2 1 ABC transporter T2SSE PF00437.20 CCV00258.1 - 0.012 14.7 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 CCV00258.1 - 0.058 13.9 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 CCV00258.1 - 0.06 12.3 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.9 CCV00258.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CCV00258.1 - 0.065 12.7 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 CCV00258.1 - 0.074 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CCV00258.1 - 0.077 12.6 0.0 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CCV00258.1 - 0.078 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 CCV00258.1 - 0.13 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 CCV00258.1 - 0.28 11.5 1.0 2.7 8.3 1.0 2.3 1 1 0 1 1 1 0 AAA domain HECT PF00632.25 CCV00259.1 - 2.3e-71 240.8 0.0 3.3e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CLASP_N PF12348.8 CCV00260.1 - 3.3e-55 187.1 0.5 1.1e-52 178.9 0.0 3.2 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.22 CCV00260.1 - 1.4e-07 31.1 8.1 0.19 12.1 0.0 7.1 7 0 0 7 7 7 3 HEAT repeat DUF3361 PF11841.8 CCV00260.1 - 0.26 11.2 2.1 0.67 9.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Rep_fac_C PF08542.11 CCV00261.1 - 4.2e-23 81.6 0.2 2.5e-22 79.1 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_assoc_2 PF16193.5 CCV00261.1 - 8e-05 22.9 0.0 0.00022 21.5 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain DEAD PF00270.29 CCV00261.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.29 CCV00261.1 - 0.024 15.1 0.1 0.041 14.3 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CCV00261.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DMA PF03474.14 CCV00261.1 - 0.19 11.3 0.6 0.77 9.4 0.2 2.2 1 1 1 2 2 2 0 DMRTA motif PX PF00787.24 CCV00262.1 - 1.1e-19 70.5 0.1 2.2e-19 69.5 0.1 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CCV00262.1 - 0.00035 20.2 2.6 0.17 11.4 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like FAM92 PF06730.11 CCV00262.1 - 0.055 12.9 0.2 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 FAM92 protein ubiquitin PF00240.23 CCV00263.1 - 1.4e-32 111.3 0.5 2e-32 110.7 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CCV00263.1 - 3e-14 52.6 0.3 4.4e-14 52.1 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.16 CCV00263.1 - 1.1e-09 38.3 4.7 2e-09 37.5 4.7 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.6 CCV00263.1 - 0.00015 22.1 0.1 0.00058 20.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCV00263.1 - 0.0093 16.1 0.0 0.024 14.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CCV00263.1 - 0.015 15.7 0.1 0.025 14.9 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 CCV00263.1 - 0.046 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rubredoxin_2 PF18073.1 CCV00263.1 - 0.086 12.6 1.8 0.21 11.4 0.7 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain Aminotran_1_2 PF00155.21 CCV00264.1 - 4.2e-69 233.4 0.0 4.8e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SMC_Nse1 PF07574.13 CCV00265.1 - 2e-20 73.5 0.0 2.6e-19 69.9 0.0 2.0 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CCV00265.1 - 4.3e-06 26.9 12.2 7.2e-06 26.2 12.2 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 CCV00265.1 - 0.011 16.0 5.6 0.02 15.2 5.6 1.4 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H PF13771.6 CCV00265.1 - 0.24 11.7 7.5 0.71 10.2 7.6 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain MTHFR PF02219.17 CCV00266.1 - 4.6e-105 351.0 0.0 6.5e-105 350.6 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Actin PF00022.19 CCV00267.1 - 6e-20 71.2 0.0 4e-09 35.6 0.0 3.1 3 0 0 3 3 3 3 Actin Actin_micro PF17003.5 CCV00267.1 - 1.3e-08 34.5 0.0 2e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 CCV00267.1 - 0.0036 16.2 0.0 0.93 8.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein SAP PF02037.27 CCV00268.1 - 6.2e-11 41.8 1.0 1e-10 41.1 1.0 1.4 1 0 0 1 1 1 1 SAP domain FANC_SAP PF18081.1 CCV00268.1 - 0.55 10.4 2.8 0.77 10.0 1.2 2.1 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain IGPD PF00475.18 CCV00269.1 - 5.2e-56 189.0 0.3 6.8e-56 188.6 0.3 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase ANAPC10 PF03256.16 CCV00269.1 - 0.077 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) WD40 PF00400.32 CCV00270.1 - 1.2e-07 32.3 7.1 7.4 7.6 0.0 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Dynein_IC2 PF11540.8 CCV00270.1 - 0.046 13.7 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 SAC3_GANP PF03399.16 CCV00271.1 - 3.6e-20 72.6 10.3 4.5e-12 46.0 0.4 2.4 2 1 0 3 3 3 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CCV00271.1 - 0.00032 20.7 0.1 0.00068 19.6 0.1 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family GHMP_kinases_N PF00288.26 CCV00272.1 - 1.1e-10 41.6 0.1 2.1e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Nuf2 PF03800.14 CCV00273.1 - 2e-37 128.4 0.4 5.3e-37 127.0 0.4 1.7 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 CCV00273.1 - 9.4e-24 83.7 21.5 9.4e-24 83.7 21.5 4.0 1 1 3 4 4 4 1 Designed helical repeat protein 10 domain Apc13p PF05839.11 CCV00273.1 - 0.017 15.3 3.5 0.039 14.2 0.2 3.0 2 1 0 2 2 2 0 Apc13p protein YojJ PF10372.9 CCV00273.1 - 0.44 10.7 7.4 4.5 7.4 0.1 3.6 3 2 2 5 5 5 0 Bacterial membrane-spanning protein N-terminus HALZ PF02183.18 CCV00273.1 - 2.3 8.5 13.2 3 8.2 0.8 4.3 4 1 0 4 4 4 0 Homeobox associated leucine zipper DUF2935 PF11155.8 CCV00273.1 - 3.1 8.1 9.9 1.5 9.1 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) Baculo_PEP_C PF04513.12 CCV00273.1 - 7.4 6.6 14.3 2.8 8.0 4.4 3.3 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glutaredoxin PF00462.24 CCV00274.1 - 7.3e-18 64.5 0.1 9.6e-17 61.0 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 CCV00274.1 - 4.6e-11 42.6 0.0 7.8e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CCV00274.1 - 7e-05 23.1 0.0 0.06 13.7 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CCV00274.1 - 0.025 15.0 0.0 0.21 12.1 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin-like domain GST_N_3 PF13417.6 CCV00274.1 - 0.027 14.9 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Phosducin PF02114.16 CCV00274.1 - 0.18 10.7 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Phosducin UCH PF00443.29 CCV00275.1 - 8.2e-73 245.1 0.0 9.9e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCV00275.1 - 5.5e-13 49.2 0.0 8.7e-05 22.3 0.0 3.1 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CCV00275.1 - 3.3e-08 34.0 0.0 5.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 DUSP domain PhnA_Zn_Ribbon PF08274.12 CCV00275.1 - 0.08 12.9 0.6 9.8 6.2 0.0 2.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.10 CCV00275.1 - 0.31 11.2 0.7 4.1 7.6 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DUF2420 PF10336.9 CCV00276.1 - 3.9e-12 46.1 0.1 1.2e-11 44.5 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2420) Hydrolase_4 PF12146.8 CCV00278.1 - 5e-43 147.1 0.0 6.1e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCV00278.1 - 2.8e-12 46.9 0.1 1.1e-10 41.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCV00278.1 - 8.7e-12 46.1 1.5 1.2e-11 45.6 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CCV00278.1 - 1.4e-05 24.7 0.1 0.0001 21.9 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CCV00278.1 - 5.3e-05 23.1 0.0 0.00096 19.0 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CCV00278.1 - 0.0046 16.8 0.0 0.065 13.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 CCV00278.1 - 0.009 15.6 0.0 0.072 12.6 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.20 CCV00278.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 CCV00278.1 - 0.073 12.8 0.0 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF900 PF05990.12 CCV00278.1 - 0.2 11.1 0.1 2.3 7.6 0.1 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Histone PF00125.24 CCV00279.1 - 4.6e-51 172.6 2.8 5.1e-51 172.4 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CCV00279.1 - 6.7e-05 23.2 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CCV00279.1 - 0.00017 21.6 0.8 0.00023 21.3 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CCV00279.1 - 0.00018 22.1 1.6 0.00022 21.9 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CCV00279.1 - 0.0014 18.8 0.1 0.0027 17.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CCV00279.1 - 0.037 14.1 0.2 0.058 13.5 0.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CCV00279.1 - 0.11 12.6 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 CCV00280.1 - 4.7e-08 33.1 0.1 5.7e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CCV00280.1 - 0.00029 20.9 0.1 0.00044 20.4 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CCV00280.1 - 0.00046 20.4 0.1 0.00094 19.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CCV00280.1 - 0.00057 20.2 0.0 0.00074 19.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 CCV00280.1 - 0.00065 20.1 0.1 0.00073 19.9 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CCV00280.1 - 0.061 13.4 0.0 0.069 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Thiolase_N PF00108.23 CCV00281.1 - 1e-79 267.6 5.1 1.7e-79 266.9 3.8 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CCV00281.1 - 5.7e-43 145.5 2.1 6.6e-43 145.3 0.7 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CCV00281.1 - 0.0094 15.6 0.2 0.0094 15.6 0.2 3.5 4 0 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 CCV00281.1 - 0.044 13.9 0.7 0.19 11.9 0.1 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Cyclin PF08613.11 CCV00282.1 - 2.5e-38 132.0 6.4 6.3e-23 81.9 0.3 2.5 3 0 0 3 3 3 2 Cyclin LIP PF03583.14 CCV00283.1 - 2.5e-47 161.6 0.0 3.3e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase ArgJ PF01960.18 CCV00284.1 - 4e-123 410.9 0.0 5e-123 410.6 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Zip PF02535.22 CCV00285.1 - 3.3e-60 204.1 6.6 4e-60 203.8 6.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter CwfJ_C_1 PF04677.15 CCV00286.1 - 1.6e-14 53.8 0.0 2.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Pheromone PF08015.11 CCV00286.1 - 1.8 9.6 8.3 0.98 10.5 0.7 3.5 3 1 0 3 3 3 0 Fungal mating-type pheromone CwfJ_C_2 PF04676.14 CCV00287.1 - 4e-33 114.2 0.0 5.5e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 CCV00287.1 - 9e-06 25.6 0.1 1.3e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Ribosomal_S4e PF00900.20 CCV00288.1 - 8.6e-35 118.5 0.3 2.1e-34 117.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 CCV00288.1 - 9.8e-23 79.6 0.1 1.8e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CCV00288.1 - 7.5e-19 67.6 6.2 7.5e-19 67.6 6.2 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 CCV00288.1 - 3.2e-05 23.6 0.1 9.8e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 CCV00288.1 - 0.00073 19.4 3.2 0.0011 18.9 1.6 2.3 2 0 0 2 2 2 1 KOW motif DnaJ-X PF14308.6 CCV00289.1 - 5.7e-63 212.2 0.2 5.7e-63 212.2 0.2 1.9 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CCV00289.1 - 1e-17 64.0 0.7 3.8e-17 62.2 0.2 2.3 2 0 0 2 2 2 1 DnaJ domain Turandot PF07240.11 CCV00289.1 - 0.18 11.8 1.1 13 5.8 0.0 3.0 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot TFIIIC_delta PF12657.7 CCV00290.1 - 1.9e-13 50.8 0.1 8.7e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 CCV00290.1 - 1.6e-08 34.5 1.1 3.2e-08 33.5 1.1 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TPT PF03151.16 CCV00291.1 - 9.4e-53 179.4 17.9 1.4e-52 178.8 17.9 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family BAG PF02179.16 CCV00291.1 - 8.5e-17 61.4 0.1 1.5e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 BAG domain EamA PF00892.20 CCV00291.1 - 1.6e-12 47.7 25.9 1.2e-08 35.2 10.1 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CCV00291.1 - 4.2e-11 42.6 15.1 6.3e-11 42.0 15.1 1.3 1 0 0 1 1 1 1 UAA transporter family ubiquitin PF00240.23 CCV00291.1 - 1.3e-05 24.8 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Nuc_sug_transp PF04142.15 CCV00291.1 - 0.00024 20.4 8.5 0.013 14.7 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TMEM234 PF10639.9 CCV00291.1 - 0.29 11.2 6.8 5.1 7.2 1.1 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 Multi_Drug_Res PF00893.19 CCV00291.1 - 1.1 10.0 7.5 0.2 12.3 2.0 2.3 2 0 0 2 2 2 0 Small Multidrug Resistance protein CEP63 PF17045.5 CCV00292.1 - 0.14 12.0 0.3 0.22 11.4 0.3 1.1 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa DEAD PF00270.29 CCV00293.1 - 5.7e-46 156.5 0.0 9.2e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCV00293.1 - 4.8e-23 81.6 0.0 1.3e-22 80.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCV00293.1 - 3.1e-19 69.0 0.1 7.7e-19 67.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCV00293.1 - 3.3e-07 30.5 0.0 7.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCV00293.1 - 0.13 12.5 1.0 0.79 10.0 1.0 2.4 1 1 0 1 1 1 0 AAA domain LPD30 PF18850.1 CCV00293.1 - 0.26 11.1 1.6 0.55 10.0 1.6 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 GRIN_C PF15235.6 CCV00293.1 - 0.92 9.7 6.4 0.21 11.8 2.6 1.9 2 0 0 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus Mito_carr PF00153.27 CCV00294.1 - 3.6e-30 103.7 1.8 1.5e-15 56.8 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein MatE PF01554.18 CCV00295.1 - 6e-45 152.8 33.1 1.7e-24 86.3 7.6 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 CCV00295.1 - 2.2e-07 31.0 20.3 4.1e-05 23.7 8.8 3.7 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain PsbN PF02468.15 CCV00295.1 - 4.3 7.3 5.9 1.4 8.8 0.4 3.1 3 0 0 3 3 3 0 Photosystem II reaction centre N protein (psbN) DnaJ PF00226.31 CCV00297.1 - 1.3e-21 76.4 1.9 2.7e-21 75.5 0.8 2.2 2 0 0 2 2 2 1 DnaJ domain PAT1 PF09770.9 CCV00297.1 - 0.18 10.1 4.3 0.23 9.7 4.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LCD1 PF09798.9 CCV00297.1 - 0.22 10.0 0.8 0.36 9.3 0.6 1.4 1 1 1 2 2 2 0 DNA damage checkpoint protein Fib_alpha PF08702.10 CCV00298.1 - 0.4 10.9 2.0 2 8.6 0.5 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family BshC PF10079.9 CCV00298.1 - 0.69 8.6 4.9 0.58 8.8 2.2 2.1 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC Apo-CII PF05355.11 CCV00298.1 - 2.3 8.4 7.4 52 4.1 0.1 3.8 3 0 0 3 3 3 0 Apolipoprotein C-II Aha1_N PF09229.11 CCV00299.1 - 4.9e-31 107.8 0.0 6.7e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CCV00299.1 - 7.7e-17 61.7 0.0 1.9e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein DUF4085 PF13315.6 CCV00299.1 - 0.0086 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4085) RPN6_N PF18055.1 CCV00300.1 - 7.9e-33 113.3 8.3 2.8e-32 111.5 5.3 3.0 2 1 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CCV00300.1 - 9.6e-10 38.9 2.3 1.1e-09 38.7 0.5 2.0 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 CCV00300.1 - 0.013 15.2 0.1 0.032 13.9 0.1 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 SRPRB PF09439.10 CCV00300.1 - 0.026 13.9 1.0 0.05 13.0 1.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TPR_6 PF13174.6 CCV00300.1 - 0.76 10.5 4.9 3 8.7 0.0 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCV00300.1 - 9.4 7.0 9.8 68 4.2 0.2 5.0 6 1 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 CCV00301.1 - 9.1e-48 162.2 1.3 1.3e-47 161.7 1.3 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CCV00301.1 - 1.2e-12 48.2 0.1 3.4e-12 46.8 0.1 1.8 1 0 0 1 1 1 1 PCI domain NARP1 PF12569.8 CCV00301.1 - 0.0059 15.6 0.1 0.0086 15.0 0.1 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 ANAPC5 PF12862.7 CCV00301.1 - 0.0062 16.6 0.6 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_2 PF07719.17 CCV00301.1 - 0.052 13.7 1.5 0.93 9.8 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 CCV00302.1 - 0.00028 20.9 0.0 0.00066 19.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 CCV00302.1 - 0.00048 19.8 0.2 0.38 10.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat UBA PF00627.31 CCV00302.1 - 0.0044 16.9 0.0 0.026 14.4 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain TPR_2 PF07719.17 CCV00302.1 - 0.18 12.0 9.6 2.3 8.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat VHS PF00790.19 CCV00303.1 - 1.4e-35 122.2 3.0 1.4e-35 122.2 1.7 1.6 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 CCV00303.1 - 1e-15 57.0 0.1 1.9e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCV00303.1 - 2e-14 53.2 0.5 4.7e-14 52.0 0.5 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCV00303.1 - 9e-12 44.5 0.1 2e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 CCV00303.1 - 1.8e-08 34.6 0.1 6.3e-08 32.8 0.1 2.0 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 CCV00303.1 - 0.0011 18.8 2.7 0.0011 18.8 2.7 2.3 2 0 0 2 2 2 1 Ubiquitin interaction motif Hrs_helical PF12210.8 CCV00303.1 - 0.97 10.0 10.3 0.055 14.0 1.3 3.0 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Q_salvage PF10343.9 CCV00304.1 - 0.00015 21.5 0.0 0.00026 20.7 0.0 1.6 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Mitoc_mL59 PF18126.1 CCV00305.1 - 3.2e-26 92.1 4.5 4.6e-26 91.6 4.5 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 UCH_1 PF13423.6 CCV00306.1 - 2.6e-68 231.0 0.0 3.4e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 CCV00306.1 - 4.8e-08 33.7 0.0 1.8e-07 31.8 0.0 2.0 1 1 0 1 1 1 1 Exonuclease ANAPC4_WD40 PF12894.7 CCV00306.1 - 0.0039 17.5 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain FlaG PF03646.15 CCV00306.1 - 0.033 14.4 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 FlaG protein UCH PF00443.29 CCV00306.1 - 0.071 12.6 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Ge1_WD40 PF16529.5 CCV00306.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PRIMA1 PF16101.5 CCV00306.1 - 3 7.9 7.0 21 5.2 3.5 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Paf1 PF03985.13 CCV00307.1 - 2.2e-43 148.8 1.5 7.1e-29 101.1 0.0 2.3 2 0 0 2 2 2 2 Paf1 Smr PF01713.21 CCV00308.1 - 1.2e-07 32.0 0.0 2.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 CCV00308.1 - 5e-05 23.1 8.4 0.001 18.9 1.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCV00308.1 - 0.002 18.1 10.7 0.28 11.3 2.1 3.2 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CCV00308.1 - 0.0055 16.5 15.5 0.045 13.6 4.9 3.6 2 2 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CCV00308.1 - 0.0055 16.9 4.1 0.044 14.0 4.1 2.1 1 1 0 1 1 1 1 Zinc-finger containing family zf-C3H1 PF10650.9 CCV00308.1 - 0.0078 15.9 6.0 0.26 11.0 1.1 2.4 2 0 0 2 2 2 2 Putative zinc-finger domain zf-CCCH_2 PF14608.6 CCV00308.1 - 0.0087 16.5 9.8 0.035 14.6 2.5 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CCV00308.1 - 0.66 10.7 3.3 8.5 7.1 0.2 2.3 1 1 1 2 2 2 0 Torus domain Tim44 PF04280.15 CCV00309.1 - 6.9e-33 113.8 0.0 5e-32 111.0 0.0 2.4 3 0 0 3 3 3 1 Tim44-like domain Seryl_tRNA_N PF02403.22 CCV00309.1 - 0.008 16.4 1.5 0.016 15.4 1.5 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Pex19 PF04614.12 CCV00309.1 - 0.1 12.4 1.8 0.19 11.4 1.8 1.4 1 0 0 1 1 1 0 Pex19 protein family CIA30 PF08547.12 CCV00310.1 - 1.7e-18 67.2 0.0 4.7e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 CCV00310.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain Lipase_3 PF01764.25 CCV00312.1 - 1.2e-22 80.3 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_9 PF10081.9 CCV00312.1 - 0.0027 16.8 0.2 0.051 12.6 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta-hydrolase family PGAP1 PF07819.13 CCV00312.1 - 0.0037 17.0 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 CCV00312.1 - 0.0069 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 CCV00312.1 - 0.0087 16.7 0.0 0.018 15.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCV00312.1 - 0.013 14.8 0.2 0.051 12.8 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 CCV00312.1 - 0.015 14.9 0.0 0.096 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Cutinase PF01083.22 CCV00312.1 - 0.053 13.5 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase LCAT PF02450.15 CCV00312.1 - 0.12 11.5 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 CCV00312.1 - 0.18 11.4 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF155 PF02582.14 CCV00313.1 - 1.5e-18 67.5 0.3 5.3e-18 65.7 0.3 1.7 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ALG3 PF05208.13 CCV00314.1 - 4.9e-90 302.5 6.9 6.3e-90 302.2 6.9 1.0 1 0 0 1 1 1 1 ALG3 protein UPF0121 PF03661.13 CCV00316.1 - 2.9e-51 174.2 3.3 3.6e-51 173.9 3.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) RNA_pol_Rpb1_5 PF04998.17 CCV00317.1 - 2.1e-102 342.1 0.0 3e-102 341.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CCV00317.1 - 9e-101 337.3 0.0 1.2e-100 336.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CCV00317.1 - 4.6e-74 248.2 0.0 8e-74 247.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CCV00317.1 - 6.4e-59 199.0 0.0 1.4e-58 197.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 CCV00317.1 - 2.4e-47 160.3 0.4 5.1e-47 159.3 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 CCV00317.1 - 7.3e-46 156.0 0.0 1.6e-45 154.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CCV00317.1 - 3.2e-37 126.8 0.0 7.5e-37 125.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Pkinase PF00069.25 CCV00320.1 - 4.9e-65 219.5 0.0 2.2e-64 217.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Abhydrolase_3 PF07859.13 CCV00320.1 - 7.4e-46 156.7 0.3 3e-45 154.7 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pkinase_Tyr PF07714.17 CCV00320.1 - 1.1e-27 97.0 0.0 1.9e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Say1_Mug180 PF10340.9 CCV00320.1 - 6.8e-11 41.6 0.0 4.4e-10 39.0 0.0 2.0 1 1 0 1 1 1 1 Steryl acetyl hydrolase Kdo PF06293.14 CCV00320.1 - 0.0032 16.8 0.0 0.0092 15.4 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CCV00320.1 - 0.006 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL COesterase PF00135.28 CCV00320.1 - 0.01 14.7 0.0 0.2 10.5 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family Pkinase_fungal PF17667.1 CCV00320.1 - 0.014 14.2 0.0 0.034 12.9 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CCV00320.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family NAC PF01849.18 CCV00321.1 - 2.1e-19 69.3 0.0 4.5e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 CCV00321.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Proteasome PF00227.26 CCV00322.1 - 1.8e-59 200.4 0.0 2.7e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCV00322.1 - 1.4e-13 50.3 0.4 4e-13 48.8 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SNARE_assoc PF09335.11 CCV00323.1 - 2.7e-17 63.4 7.9 3.8e-17 62.9 3.3 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4396 PF14342.6 CCV00323.1 - 7.6 6.9 13.3 0.71 10.2 6.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4396) PUF PF00806.19 CCV00324.1 - 9e-10 37.7 0.0 0.00021 20.8 0.0 3.2 3 0 0 3 3 3 2 Pumilio-family RNA binding repeat VipB PF05943.12 CCV00324.1 - 0.21 10.3 0.3 0.32 9.7 0.3 1.2 1 0 0 1 1 1 0 Type VI secretion protein, EvpB/VC_A0108, tail sheath Stealth_CR3 PF17102.5 CCV00324.1 - 9.2 6.3 6.2 1.1 9.3 0.2 2.6 3 0 0 3 3 3 0 Stealth protein CR3, conserved region 3 RNase_PH PF01138.21 CCV00325.1 - 1.5e-20 74.1 0.0 2e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCV00325.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 ABC_tran PF00005.27 CCV00326.1 - 1.4e-43 148.7 0.0 1.9e-21 77.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CCV00326.1 - 9.9e-25 86.4 4.2 9.9e-25 86.4 4.2 2.9 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 CCV00326.1 - 6.5e-15 55.7 6.7 0.00012 22.1 0.0 4.6 4 1 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system GHMP_kinases_N PF00288.26 CCV00326.1 - 1e-14 54.5 3.1 5.2e-14 52.2 3.1 2.3 1 0 0 1 1 1 1 GHMP kinases N terminal domain SMC_N PF02463.19 CCV00326.1 - 3.1e-08 33.3 0.1 0.019 14.4 0.0 4.2 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CCV00326.1 - 1.4e-06 28.4 0.0 0.032 14.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CCV00326.1 - 1.9e-06 27.5 0.1 0.032 14.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCV00326.1 - 5.8e-06 26.3 0.0 0.046 13.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase GHMP_kinases_C PF08544.13 CCV00326.1 - 5.1e-05 23.6 0.1 0.0002 21.7 0.1 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal AAA_23 PF13476.6 CCV00326.1 - 0.0001 22.9 2.8 0.76 10.2 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 CCV00326.1 - 0.00013 22.3 0.1 0.56 10.5 0.1 3.4 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 CCV00326.1 - 0.00025 21.5 3.5 0.64 10.4 0.0 3.9 3 1 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 CCV00326.1 - 0.00027 20.9 0.1 0.57 10.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 CCV00326.1 - 0.0003 21.1 0.4 0.83 9.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 CCV00326.1 - 0.00044 20.1 0.0 0.38 10.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain MeaB PF03308.16 CCV00326.1 - 0.00089 18.3 0.0 0.53 9.2 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 CCV00326.1 - 0.0013 18.5 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CCV00326.1 - 0.0017 18.9 0.0 6.5 7.3 0.0 4.3 5 0 0 5 5 4 0 AAA domain AAA_33 PF13671.6 CCV00326.1 - 0.0045 17.2 0.0 3.7 7.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCV00326.1 - 0.0051 17.2 0.0 1.5 9.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 CCV00326.1 - 0.0079 15.7 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 CCV00326.1 - 0.0091 16.1 0.5 0.14 12.2 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain DUF815 PF05673.13 CCV00326.1 - 0.014 14.5 0.0 0.32 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 CCV00326.1 - 0.022 14.3 0.0 7.6 6.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CCV00326.1 - 0.025 14.8 0.0 5.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 CCV00326.1 - 0.053 13.9 0.0 7.7 7.0 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CCV00326.1 - 0.065 12.3 0.0 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 CCV00326.1 - 0.083 12.5 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 CCV00326.1 - 0.13 12.2 0.0 4.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CCV00326.1 - 0.17 10.8 0.0 0.32 9.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.22 CCV00326.1 - 0.17 11.0 0.1 13 4.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF1467 PF07330.12 CCV00326.1 - 0.21 11.5 0.2 7.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) BSD PF03909.17 CCV00327.1 - 1.4e-17 63.4 0.1 1.5e-16 60.1 0.3 2.3 2 0 0 2 2 2 1 BSD domain PH_TFIIH PF08567.11 CCV00327.1 - 5.1e-16 58.8 0.0 8.8e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DtxR PF18357.1 CCV00327.1 - 0.063 13.0 0.7 0.13 12.0 0.7 1.5 1 0 0 1 1 1 0 Diphteria toxin repressor SH3 domain CDC37_N PF03234.14 CCV00328.1 - 1.3e-36 126.3 0.2 1.3e-36 126.3 0.2 3.1 3 1 1 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 CCV00328.1 - 3.6e-26 91.4 1.1 6.9e-26 90.5 0.5 1.7 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 CCV00328.1 - 1e-15 57.6 2.0 1.7e-15 56.9 0.0 2.4 3 0 0 3 3 3 1 Cdc37 C terminal domain DUF3712 PF12505.8 CCV00331.1 - 2.4e-25 89.2 1.9 3.2e-25 88.8 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF3712 PF12505.8 CCV00332.1 - 2.1e-42 144.3 14.9 4.8e-27 94.7 0.9 5.2 5 0 0 5 5 5 4 Protein of unknown function (DUF3712) LEA_2 PF03168.13 CCV00332.1 - 1.2e-07 32.2 1.5 0.00071 20.1 0.1 3.4 3 0 0 3 3 3 2 Late embryogenesis abundant protein Actin PF00022.19 CCV00333.1 - 1.1e-26 93.4 0.0 4.8e-18 64.9 0.0 2.3 2 0 0 2 2 2 2 Actin NAD_binding_5 PF07994.12 CCV00334.1 - 2.9e-145 483.6 0.0 3.4e-145 483.4 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CCV00334.1 - 1.4e-43 147.5 0.0 2.5e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF89 PF01937.19 CCV00335.1 - 6.1e-12 45.2 0.0 1.3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF89 Ala_racemase_N PF01168.20 CCV00335.1 - 6.3e-09 35.8 0.1 7.3e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 Alanine racemase, N-terminal domain Sulfate_transp PF00916.20 CCV00337.1 - 1.6e-65 221.4 24.9 2.3e-65 220.8 24.9 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 CCV00337.1 - 2.2e-12 46.9 0.0 4.7e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 CCV00337.1 - 9.6e-11 41.4 0.7 9.6e-10 38.1 0.0 2.4 1 1 1 2 2 2 1 STAS domain NCBP3 PF10309.9 CCV00338.1 - 1.8e-14 53.3 0.0 3.1e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 DEAD PF00270.29 CCV00339.1 - 3.3e-45 154.0 0.9 4.4e-45 153.6 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCV00339.1 - 5.1e-32 110.5 0.3 2e-31 108.6 0.1 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCV00339.1 - 1.9e-06 28.0 0.0 3.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CCV00339.1 - 0.00015 22.1 0.3 0.0034 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCV00339.1 - 0.00058 19.6 0.1 0.0011 18.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain tRNA-synt_1b PF00579.25 CCV00339.1 - 0.068 12.5 0.2 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.14 CCV00339.1 - 0.09 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Helicase CMS1 PF14617.6 CCV00339.1 - 0.095 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PMT_4TMC PF16192.5 CCV00340.1 - 6.3e-56 189.1 11.1 6.3e-56 189.1 11.1 1.5 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCV00340.1 - 8.1e-20 71.5 0.0 1.2e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 MIR domain PMT PF02366.18 CCV00340.1 - 6.3e-05 22.7 2.6 0.00015 21.5 2.6 1.7 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Abhydrolase_9_N PF15420.6 CCV00340.1 - 0.15 12.0 1.3 0.37 10.7 0.4 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF997 PF06196.12 CCV00340.1 - 4.8 7.3 8.1 1.8 8.6 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF997) WD40 PF00400.32 CCV00341.1 - 7.1e-46 153.3 18.5 3.3e-12 46.7 1.4 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCV00341.1 - 8.3e-17 61.3 2.3 0.00012 22.4 0.1 5.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCV00341.1 - 4.2e-07 29.2 2.2 0.033 13.2 0.0 4.9 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 CCV00341.1 - 4.2e-06 25.4 0.0 8.1e-06 24.4 0.0 1.5 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 CCV00341.1 - 8.2e-06 24.7 9.9 0.81 8.3 0.1 4.6 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CCV00341.1 - 4.9e-05 22.2 1.8 2.9 6.5 0.0 4.7 1 1 3 5 5 5 2 Nup133 N terminal like PALB2_WD40 PF16756.5 CCV00341.1 - 0.00028 19.9 2.0 0.001 18.1 0.1 2.5 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 CCV00341.1 - 0.00059 19.6 0.2 0.92 9.2 0.0 3.4 1 1 2 3 3 3 2 TUP1-like enhancer of split Gmad1 PF10647.9 CCV00341.1 - 0.0091 15.8 2.8 11 5.7 0.4 3.6 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain Coatomer_WDAD PF04053.14 CCV00341.1 - 0.037 13.1 0.0 0.061 12.4 0.0 1.3 1 1 0 1 1 1 0 Coatomer WD associated region dsrm PF00035.26 CCV00342.1 - 3.4e-07 30.9 0.0 5.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 CCV00342.1 - 5.5e-05 23.7 0.0 0.00011 22.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CCV00342.1 - 6.4e-05 23.1 0.0 0.00015 22.0 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease-III-like SRP54 PF00448.22 CCV00343.1 - 1.3e-34 119.6 0.0 1.3e-32 113.0 0.0 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CCV00343.1 - 3.8e-07 30.3 8.1 5.3e-07 29.8 8.1 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal MeaB PF03308.16 CCV00343.1 - 1.4e-06 27.5 0.0 4.2e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54_N PF02881.19 CCV00343.1 - 1.1e-05 25.6 0.1 2.5e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 CCV00343.1 - 0.0078 16.0 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CCV00343.1 - 0.016 15.3 4.1 0.016 15.3 0.0 2.9 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 CCV00343.1 - 0.036 14.2 0.8 0.34 11.0 0.2 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase ArsA_ATPase PF02374.15 CCV00343.1 - 0.037 13.2 0.0 0.58 9.3 0.0 2.4 1 1 0 1 1 1 0 Anion-transporting ATPase Mo25 PF08569.11 CCV00343.1 - 0.04 13.3 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Mo25-like Fer4_NifH PF00142.18 CCV00343.1 - 0.093 12.2 0.1 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NTPase_1 PF03266.15 CCV00343.1 - 0.17 11.8 0.0 0.72 9.7 0.0 2.0 1 1 0 1 1 1 0 NTPase Na_H_Exchanger PF00999.21 CCV00344.1 - 4.7e-08 32.2 0.3 6e-08 31.9 0.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Abhydrolase_1 PF00561.20 CCV00345.1 - 3.9e-24 85.7 0.1 1.6e-23 83.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCV00345.1 - 5.6e-14 52.0 0.1 6.4e-10 38.7 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCV00345.1 - 8.8e-12 46.1 3.7 1.8e-11 45.1 3.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CCV00345.1 - 0.0001 21.8 0.1 0.077 12.5 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S10 PF00450.22 CCV00345.1 - 0.027 13.9 0.2 0.52 9.7 0.0 2.1 2 0 0 2 2 2 0 Serine carboxypeptidase Abhydrolase_2 PF02230.16 CCV00345.1 - 0.03 14.1 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.14 CCV00345.1 - 0.031 13.6 0.0 0.44 9.8 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_4 PF08386.10 CCV00345.1 - 0.051 13.7 0.0 5 7.3 0.0 2.3 2 0 0 2 2 2 0 TAP-like protein SWIRM-assoc_2 PF16496.5 CCV00346.1 - 2.1e-39 135.6 0.4 2.1e-39 135.6 0.4 1.9 2 1 0 2 2 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 CCV00346.1 - 8.8e-32 109.3 0.2 2.2e-31 108.0 0.2 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 CCV00346.1 - 1.9e-28 98.3 11.0 5.4e-28 96.8 11.0 1.9 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 CCV00346.1 - 7.1e-10 38.9 0.0 1.7e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCV00346.1 - 1.6e-07 31.5 0.1 8.4e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 CCV00346.1 - 7.3e-07 28.9 1.6 1.3e-06 28.1 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_7 PF15963.5 CCV00346.1 - 0.04 13.8 1.3 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Myb DNA-binding like RhoGAP PF00620.27 CCV00347.1 - 8.6e-41 139.3 0.0 1.9e-40 138.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 CCV00347.1 - 8.7e-10 39.1 0.0 1.9e-08 34.7 0.0 3.0 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 CCV00347.1 - 1.2e-06 28.7 0.0 7.1e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif NADH_B2 PF14813.6 CCV00347.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Cellulase PF00150.18 CCV00348.1 - 3.4e-18 66.1 8.0 8e-18 64.9 8.0 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 CCV00349.1 - 2.4e-08 33.7 0.0 3.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TPR_2 PF07719.17 CCV00351.1 - 2.1e-07 30.5 10.5 0.89 9.8 0.0 8.2 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCV00351.1 - 2.4e-07 31.0 24.2 21 6.3 0.0 11.2 11 1 1 12 12 10 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CCV00351.1 - 1.3e-05 25.2 9.3 0.55 10.2 0.4 6.7 7 1 1 8 8 8 1 Mad3/BUB1 homology region 1 TPR_19 PF14559.6 CCV00351.1 - 8.6e-05 23.0 3.8 1.7 9.2 0.9 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCV00351.1 - 0.00013 22.2 11.5 6.1 7.2 0.0 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 CCV00351.1 - 0.00014 22.0 1.1 4.1 8.0 0.0 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat MIT PF04212.18 CCV00351.1 - 0.00058 19.9 1.9 0.013 15.5 0.1 4.2 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_15 PF13429.6 CCV00351.1 - 0.0066 15.7 4.6 0.093 11.9 0.4 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCV00351.1 - 0.0066 16.6 16.4 2.8 8.4 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CCV00351.1 - 0.032 13.4 5.1 14 4.7 0.0 5.0 3 2 1 4 4 4 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 CCV00351.1 - 0.15 12.7 11.5 65 4.5 0.0 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCV00351.1 - 0.29 11.3 9.4 2.7 8.2 0.0 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCV00351.1 - 0.71 9.8 11.6 1.6 8.6 0.0 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 CCV00351.1 - 6.5 7.7 0.0 6.5 7.7 0.0 4.0 6 0 0 6 6 2 0 Tetratricopeptide repeat RRM_1 PF00076.22 CCV00352.1 - 4.2e-06 26.5 0.0 6.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 CCV00352.1 - 0.17 12.1 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif 2 WD40 PF00400.32 CCV00353.1 - 4.9e-14 52.5 1.6 1e-06 29.4 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Striatin PF08232.12 CCV00353.1 - 6.1e-06 26.9 0.4 1e-05 26.2 0.1 1.5 2 0 0 2 2 2 1 Striatin family Med26 PF08711.11 CCV00354.1 - 1.5e-08 34.6 0.0 2.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain S4 PF01479.25 CCV00355.1 - 6.6e-13 48.1 0.5 6.6e-13 48.1 0.5 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 CCV00355.1 - 1.8e-06 28.7 0.1 2.6e-06 28.2 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 CCV00356.1 - 2.5e-41 139.6 6.2 5.6e-41 138.5 5.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e SH3_2 PF07653.17 CCV00356.1 - 0.046 13.4 0.1 0.091 12.5 0.1 1.4 1 0 0 1 1 1 0 Variant SH3 domain DUF2868 PF11067.8 CCV00356.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Amidohydro_1 PF01979.20 CCV00357.1 - 9.2e-15 54.8 0.0 1.9e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CCV00357.1 - 9.3e-13 48.4 10.1 1.2e-08 34.9 0.0 3.6 4 0 0 4 4 4 2 Amidohydrolase family Ank_2 PF12796.7 CCV00358.1 - 1.3e-13 51.3 1.6 1.4e-11 44.8 0.7 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCV00358.1 - 2.5e-12 47.0 1.9 3e-08 34.0 1.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCV00358.1 - 5.7e-09 35.5 2.5 0.00036 20.8 0.1 4.5 4 1 1 5 5 5 2 Ankyrin repeat Ank PF00023.30 CCV00358.1 - 1.7e-08 34.5 3.5 0.00021 21.6 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CCV00358.1 - 2.7e-06 27.6 1.8 0.013 15.8 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Zip PF02535.22 CCV00358.1 - 0.065 12.4 1.1 0.066 12.4 1.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sds3 PF08598.11 CCV00359.1 - 7.4e-23 81.7 5.6 7.4e-23 81.7 5.6 1.9 2 1 0 2 2 2 1 Sds3-like XRN_M PF17846.1 CCV00359.1 - 1.1 8.1 3.6 2.2 7.1 3.6 1.4 1 0 0 1 1 1 0 Xrn1 helical domain BCDHK_Adom3 PF10436.9 CCV00360.1 - 2.1e-58 196.7 0.0 3e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CCV00360.1 - 6.5e-08 33.1 0.0 1.1e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CCV00360.1 - 9.3e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mt_ATP-synt_B PF05405.14 CCV00361.1 - 7.2e-42 142.8 9.3 8.5e-42 142.5 9.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3361 PF11841.8 CCV00361.1 - 0.4 10.6 5.3 0.68 9.9 0.4 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3361) DASH_Duo1 PF08651.10 CCV00361.1 - 0.74 9.6 4.8 43 4.0 0.3 3.1 2 1 1 3 3 3 0 DASH complex subunit Duo1 OEP PF02321.18 CCV00361.1 - 4.4 7.1 12.9 0.43 10.4 8.7 1.4 2 0 0 2 2 2 0 Outer membrane efflux protein Pkinase PF00069.25 CCV00362.1 - 1.2e-69 234.6 0.0 1.4e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCV00362.1 - 5.7e-33 114.3 0.0 9.1e-33 113.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCV00362.1 - 0.15 11.9 1.4 0.31 10.9 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CCV00362.1 - 0.22 10.4 0.0 2.1 7.2 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain VPS9 PF02204.18 CCV00363.1 - 2.2e-28 98.5 0.0 3.3e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CCV00363.1 - 1.8e-13 50.6 0.0 2e-11 44.0 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF5601) RRM_1 PF00076.22 CCV00364.1 - 0.00018 21.3 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_CoA_synt_N PF01154.17 CCV00365.1 - 4.9e-86 287.0 0.0 7.2e-86 286.5 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 CCV00365.1 - 5.2e-78 262.5 0.1 7.7e-78 261.9 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.10 CCV00365.1 - 0.00093 19.3 0.0 0.023 14.9 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AAA PF00004.29 CCV00367.1 - 1.4e-83 277.9 0.0 2.3e-41 141.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCV00367.1 - 2.2e-18 65.8 4.0 2.6e-09 36.8 0.2 3.0 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CCV00367.1 - 2.3e-13 50.2 0.0 7.7e-08 32.2 0.0 3.0 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCV00367.1 - 4.4e-13 50.0 2.4 3e-07 31.0 0.6 3.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CCV00367.1 - 3.9e-12 46.3 0.1 1.2e-05 25.3 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CCV00367.1 - 2.9e-10 40.5 0.0 8.5e-06 26.0 0.0 2.5 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CCV00367.1 - 2.3e-08 34.3 0.0 0.0012 19.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CCV00367.1 - 1e-07 32.3 1.0 0.00083 19.6 0.2 4.0 2 2 1 3 3 3 1 AAA domain TIP49 PF06068.13 CCV00367.1 - 6.7e-07 28.8 0.0 0.0086 15.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 CCV00367.1 - 2.9e-06 27.3 0.0 0.002 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCV00367.1 - 6.2e-06 26.6 0.0 0.01 16.2 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 CCV00367.1 - 4.3e-05 23.8 0.2 0.091 13.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 CCV00367.1 - 4.4e-05 23.1 0.0 0.031 13.8 0.0 3.1 3 1 0 3 3 3 1 P-loop containing dynein motor region AAA_24 PF13479.6 CCV00367.1 - 9.8e-05 22.2 0.0 0.0007 19.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CCV00367.1 - 0.0002 20.8 0.1 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CCV00367.1 - 0.00052 20.6 0.0 0.042 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CCV00367.1 - 0.00057 19.9 0.0 0.052 13.5 0.0 2.7 2 2 0 2 2 2 1 Rad17 P-loop domain AAA_3 PF07726.11 CCV00367.1 - 0.00068 19.5 0.0 0.62 9.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CCV00367.1 - 0.00096 18.9 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_11 PF13086.6 CCV00367.1 - 0.001 18.9 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CCV00367.1 - 0.0011 18.9 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CCV00367.1 - 0.0021 17.7 4.8 0.45 10.1 0.1 3.7 2 2 1 3 3 3 1 AAA domain Zeta_toxin PF06414.12 CCV00367.1 - 0.0024 17.2 0.0 0.034 13.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Hydin_ADK PF17213.3 CCV00367.1 - 0.0036 17.6 0.2 0.039 14.2 0.1 2.2 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain NACHT PF05729.12 CCV00367.1 - 0.0092 15.9 0.1 0.28 11.1 0.0 3.2 4 0 0 4 4 3 1 NACHT domain AAA_30 PF13604.6 CCV00367.1 - 0.02 14.6 0.4 0.19 11.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CCV00367.1 - 0.021 14.0 0.0 0.071 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IPT PF01745.16 CCV00367.1 - 0.021 14.2 0.1 0.98 8.8 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_17 PF13207.6 CCV00367.1 - 0.026 15.0 0.0 4.1 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CCV00367.1 - 0.044 14.3 0.0 0.27 11.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Cytidylate_kin PF02224.18 CCV00367.1 - 0.053 13.2 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase ATPase PF06745.13 CCV00367.1 - 0.056 12.8 0.0 3.6 6.9 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.6 CCV00367.1 - 0.076 13.3 0.2 0.93 9.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain SKI PF01202.22 CCV00367.1 - 0.081 13.1 0.0 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase Sigma54_activat PF00158.26 CCV00367.1 - 0.085 12.6 0.0 4.1 7.1 0.0 3.0 4 0 0 4 4 3 0 Sigma-54 interaction domain NTPase_1 PF03266.15 CCV00367.1 - 0.088 12.7 0.0 0.38 10.6 0.0 2.0 2 1 0 2 2 2 0 NTPase Sigma54_activ_2 PF14532.6 CCV00367.1 - 0.099 12.8 0.0 17 5.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 CCV00367.1 - 0.1 12.5 0.0 1.1 9.1 0.0 2.4 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 CCV00367.1 - 0.2 10.7 0.0 0.69 8.9 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 FAD_binding_3 PF01494.19 CCV00368.1 - 1.2e-15 57.6 7.6 5.3e-09 35.8 1.1 3.1 3 0 0 3 3 3 2 FAD binding domain NAD_binding_9 PF13454.6 CCV00368.1 - 0.00042 20.3 0.2 0.0011 19.0 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.10 CCV00368.1 - 0.0011 18.1 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 CCV00368.1 - 0.0097 15.0 2.1 0.017 14.2 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CCV00368.1 - 0.083 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Hpt PF01627.23 CCV00368.1 - 0.1 12.9 0.6 0.33 11.2 0.6 1.9 1 0 0 1 1 1 0 Hpt domain SMC_N PF02463.19 CCV00370.1 - 2.5e-63 213.5 0.0 3.2e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCV00370.1 - 2.6e-28 98.7 0.0 1.7e-27 96.1 0.0 2.6 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 CCV00370.1 - 3.9e-17 63.0 0.0 7.3e-11 42.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CCV00370.1 - 3.1e-15 56.8 0.2 9.1e-07 29.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CCV00370.1 - 3.9e-13 50.3 19.6 3.9e-13 50.3 19.6 5.3 3 2 1 4 4 4 1 AAA domain ABC_tran PF00005.27 CCV00370.1 - 5.1e-06 27.0 6.6 0.075 13.5 0.0 4.7 5 1 0 5 5 5 2 ABC transporter AAA_29 PF13555.6 CCV00370.1 - 0.00041 20.0 0.0 0.0017 18.1 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF1617 PF07761.12 CCV00370.1 - 0.15 12.2 0.7 0.42 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1617) EMC3_TMCO1 PF01956.16 CCV00371.1 - 2.4e-48 164.1 0.2 3.7e-48 163.5 0.2 1.3 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Ceramidase PF05875.12 CCV00372.1 - 6.8e-82 274.8 7.0 8.3e-82 274.5 7.0 1.0 1 0 0 1 1 1 1 Ceramidase Neurensin PF14927.6 CCV00372.1 - 0.48 10.1 4.7 1.1 9.0 0.0 2.9 3 0 0 3 3 3 0 Neurensin Pinin_SDK_memA PF04696.13 CCV00373.1 - 5.7e-05 23.2 3.6 5.7e-05 23.2 3.6 2.9 2 1 1 3 3 3 2 pinin/SDK/memA/ protein conserved region BAR PF03114.18 CCV00373.1 - 0.18 11.4 3.6 0.14 11.8 1.1 1.8 2 0 0 2 2 2 0 BAR domain TPR_MLP1_2 PF07926.12 CCV00373.1 - 4.2 7.4 17.3 0.11 12.5 4.1 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1348 PF07080.11 CCV00374.1 - 9.6e-54 180.8 2.3 1.1e-53 180.6 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 CCV00374.1 - 1.6e-07 31.9 0.0 2.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 CCV00374.1 - 0.0036 17.7 0.1 0.013 15.9 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 CCV00374.1 - 0.025 14.4 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase PhoLip_ATPase_C PF16212.5 CCV00375.1 - 1.9e-63 214.5 18.7 5e-63 213.2 18.7 1.7 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCV00375.1 - 2.2e-25 88.1 1.3 4.2e-25 87.2 1.3 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CCV00375.1 - 3.7e-12 46.2 0.1 3.6e-11 43.0 0.0 2.6 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCV00375.1 - 2.1e-09 38.0 3.2 9.6e-06 26.0 1.9 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CCV00375.1 - 9.1e-08 31.8 0.0 1.1e-06 28.3 0.0 2.6 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CCV00375.1 - 0.021 14.6 0.1 0.066 12.9 0.1 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 CCV00375.1 - 0.25 10.7 0.6 7.8 5.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) TMEM223 PF14640.6 CCV00376.1 - 0.00094 19.4 0.0 0.0023 18.1 0.0 1.6 2 0 0 2 2 2 1 Transmembrane protein 223 RNase_T PF00929.24 CCV00377.1 - 7.4e-15 55.9 0.0 1e-14 55.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CCV00377.1 - 0.0087 15.8 0.0 0.021 14.5 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease RabGAP-TBC PF00566.18 CCV00378.1 - 8.8e-50 169.3 0.0 1.1e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNA_pol_Rpb8 PF03870.15 CCV00379.1 - 5e-46 156.4 0.0 5.6e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 polyprenyl_synt PF00348.17 CCV00380.1 - 2e-55 187.7 0.0 2.6e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase FGGY_C PF02782.16 CCV00381.1 - 4.1e-17 62.6 0.1 2.3e-16 60.1 0.1 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CCV00381.1 - 2.7e-14 53.3 0.2 5.4e-12 45.8 0.2 3.0 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain Chon_Sulph_att PF06566.11 CCV00381.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain HEAT_EZ PF13513.6 CCV00382.1 - 1.6e-31 108.3 27.9 8.1e-14 51.8 0.0 11.6 7 3 6 13 13 13 7 HEAT-like repeat HEAT_2 PF13646.6 CCV00382.1 - 2e-19 69.8 0.8 1.5e-05 25.2 0.0 7.4 5 3 2 7 7 7 4 HEAT repeats HEAT PF02985.22 CCV00382.1 - 1.3e-17 62.3 17.8 0.00068 19.7 0.0 9.7 10 0 0 10 10 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 CCV00382.1 - 2.2e-10 41.0 0.0 0.0064 17.1 0.0 5.4 5 1 1 6 6 5 2 Vacuolar 14 Fab1-binding region DUF3437 PF11919.8 CCV00382.1 - 5e-08 32.7 0.7 0.0045 16.9 0.0 4.7 3 1 1 4 4 4 2 Domain of unknown function (DUF3437) MMS19_C PF12460.8 CCV00382.1 - 5.6e-06 25.7 5.0 0.049 12.7 0.4 4.3 4 1 0 4 4 4 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 CCV00382.1 - 3.2e-05 24.0 0.0 1.7 8.7 0.0 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 CCV00382.1 - 0.00017 21.5 10.0 0.88 9.7 0.0 7.3 8 0 0 8 8 7 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 CCV00382.1 - 0.00093 19.1 0.0 0.0039 17.1 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain DRIM PF07539.12 CCV00382.1 - 0.0019 16.6 0.2 0.062 11.6 0.0 2.9 3 0 0 3 3 3 1 Down-regulated in metastasis RTP1_C1 PF10363.9 CCV00382.1 - 0.0049 17.0 0.1 0.36 11.0 0.0 3.6 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 CCV00382.1 - 0.0087 14.7 0.6 0.4 9.2 0.1 3.1 3 0 0 3 3 3 1 Adaptin N terminal region Xpo1 PF08389.12 CCV00382.1 - 0.14 12.3 0.2 6.3 6.8 0.0 3.4 4 0 0 4 4 4 0 Exportin 1-like protein CAF1A PF12253.8 CCV00382.1 - 0.51 10.5 6.6 1.2 9.3 6.6 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A TAFH PF07531.14 CCV00382.1 - 2.2 8.5 4.8 61 3.8 0.0 4.6 4 1 1 5 5 5 0 NHR1 homology to TAF PBP1_TM PF14812.6 CCV00382.1 - 9.7 6.6 9.4 20 5.7 9.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cpn60_TCP1 PF00118.24 CCV00383.1 - 5.5e-153 510.1 0.0 6.2e-153 509.9 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sacchrp_dh_NADP PF03435.18 CCV00384.1 - 4.7e-14 52.8 0.3 9.1e-14 51.8 0.3 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 CCV00384.1 - 0.00014 21.6 0.4 0.00021 20.9 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CCV00384.1 - 0.0023 17.8 0.5 0.0042 17.0 0.5 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CCV00384.1 - 0.018 15.5 0.0 0.065 13.7 0.0 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PilX_N PF14341.6 CCV00384.1 - 0.13 12.2 1.0 11 6.1 0.0 3.8 4 0 0 4 4 4 0 PilX N-terminal UPF0086 PF01868.16 CCV00385.1 - 7.1e-20 70.7 0.0 1.2e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 E1-E2_ATPase PF00122.20 CCV00387.1 - 4.8e-53 179.4 1.2 1.7e-51 174.4 1.3 2.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CCV00387.1 - 3.1e-35 121.5 1.5 3.1e-35 121.5 1.5 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CCV00387.1 - 6.8e-25 88.6 1.4 1.6e-24 87.4 1.4 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCV00387.1 - 2.2e-12 46.5 0.0 5.8e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CCV00387.1 - 3e-12 46.5 0.0 8.5e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCV00387.1 - 5.1e-08 33.0 2.2 1.3e-05 25.1 0.7 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CCV00387.1 - 0.00019 21.9 0.0 0.00038 20.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Epimerase_2 PF02350.19 CCV00387.1 - 0.041 12.8 0.6 0.08 11.8 0.1 1.7 2 1 0 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase Hydrolase_6 PF13344.6 CCV00387.1 - 0.046 13.8 0.0 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Gate PF07670.14 CCV00387.1 - 0.066 13.5 5.7 1 9.6 1.1 3.7 3 0 0 3 3 3 0 Nucleoside recognition Mub_B2 PF17966.1 CCV00387.1 - 0.093 13.5 0.0 0.33 11.7 0.0 1.9 1 0 0 1 1 1 0 Mub B2-like domain HSP70 PF00012.20 CCV00388.1 - 1.5e-53 182.0 6.7 3.9e-50 170.6 0.0 3.0 2 2 1 3 3 3 2 Hsp70 protein GBP_C PF02841.14 CCV00388.1 - 0.011 15.2 8.7 0.018 14.5 8.7 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain MAT1 PF06391.13 CCV00388.1 - 0.068 13.0 6.6 0.17 11.7 6.6 1.6 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 MnmE_helical PF12631.7 CCV00388.1 - 0.58 10.3 5.7 11 6.1 3.9 2.6 2 1 1 3 3 3 0 MnmE helical domain Latarcin PF10279.9 CCV00388.1 - 0.73 10.3 3.8 5.1 7.6 3.6 2.3 1 1 0 1 1 1 0 Latarcin precursor SKA1 PF07160.12 CCV00388.1 - 3.4 7.5 14.7 0.6 9.9 5.7 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 IPPT PF01715.17 CCV00389.1 - 1.3e-56 192.0 0.0 3.3e-56 190.7 0.0 1.7 1 0 0 1 1 1 1 IPP transferase Peptidase_M1 PF01433.20 CCV00389.1 - 2.2e-39 135.3 0.0 3.3e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CCV00389.1 - 5.2e-34 116.7 0.8 1.2e-33 115.5 0.1 2.1 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CCV00389.1 - 3.5e-24 86.0 0.0 5.5e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain AAA_33 PF13671.6 CCV00389.1 - 0.00036 20.7 2.0 0.12 12.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CCV00389.1 - 0.0031 17.9 0.0 0.012 16.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 CCV00389.1 - 0.0033 17.2 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein IPT PF01745.16 CCV00389.1 - 0.0036 16.7 0.1 0.007 15.8 0.1 1.4 1 0 0 1 1 1 1 Isopentenyl transferase MeaB PF03308.16 CCV00389.1 - 0.0055 15.7 0.0 0.0092 15.0 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 CCV00389.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 CCV00389.1 - 0.039 13.9 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 CCV00389.1 - 0.068 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 CCV00389.1 - 0.1 12.9 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CCV00389.1 - 0.13 11.9 0.1 0.4 10.3 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.7 CCV00389.1 - 0.22 10.4 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.17 CCV00389.1 - 0.24 11.5 0.1 0.59 10.2 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain PK PF00224.21 CCV00390.1 - 1.4e-155 517.5 1.9 1.7e-155 517.2 1.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CCV00390.1 - 2.9e-33 114.6 0.0 8e-33 113.2 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CCV00390.1 - 1.2e-05 24.6 0.4 3.4e-05 23.1 0.4 1.7 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 CCV00390.1 - 0.0062 15.6 0.1 0.12 11.3 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Med5 PF08689.10 CCV00391.1 - 4.4e-12 44.7 0.0 1.4e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Mediator complex subunit Med5 Methyltransf_11 PF08241.12 CCV00392.1 - 5.5e-14 52.6 0.0 1.1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCV00392.1 - 4.5e-12 46.5 0.0 9.2e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCV00392.1 - 3.9e-11 43.6 0.0 1e-10 42.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCV00392.1 - 5.8e-08 32.4 0.0 9.3e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CCV00392.1 - 2.4e-07 30.7 0.0 3.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCV00392.1 - 4.6e-07 29.7 0.0 7.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain SNAP PF14938.6 CCV00393.1 - 1.9e-74 250.6 13.6 2.2e-74 250.4 13.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Spatacsin_C PF14649.6 CCV00393.1 - 0.00063 19.0 1.5 0.00063 19.0 1.5 1.8 1 1 1 2 2 2 1 Spatacsin C-terminus TPR_MalT PF17874.1 CCV00393.1 - 0.001 18.6 3.8 0.0028 17.1 3.8 1.9 1 1 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 CCV00393.1 - 0.052 13.6 10.9 0.69 10.1 0.0 5.0 3 1 2 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 CCV00393.1 - 0.071 13.2 0.2 0.071 13.2 0.2 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Suppressor_APC PF11414.8 CCV00393.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein TPR_1 PF00515.28 CCV00393.1 - 0.19 11.6 8.6 0.83 9.6 0.2 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 CCV00393.1 - 0.3 11.3 0.2 0.3 11.3 0.2 5.6 6 1 2 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCV00393.1 - 0.48 10.8 0.2 0.48 10.8 0.2 4.8 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCV00393.1 - 2.5 8.8 21.1 0.67 10.6 3.0 5.0 3 3 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCV00393.1 - 4.4 8.2 17.1 40 5.1 0.0 6.1 3 1 1 4 4 4 0 Tetratricopeptide repeat GatB_N PF02934.15 CCV00394.1 - 4e-102 341.3 0.0 5.3e-102 340.9 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CCV00394.1 - 1.4e-23 83.4 0.0 2e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 GatB domain PTPA PF03095.15 CCV00395.1 - 2.8e-72 243.7 0.0 3.3e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein tRNA-synt_2b PF00587.25 CCV00396.1 - 1.7e-36 125.9 0.0 3.1e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CCV00396.1 - 6.1e-18 64.8 0.1 1.4e-17 63.6 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 CCV00396.1 - 2.4e-16 59.5 0.0 4.9e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 CCV00396.1 - 2.8e-10 40.1 0.0 5.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF502 PF04367.13 CCV00396.1 - 0.17 11.8 0.0 1.2 9.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF502) CcdA PF07362.12 CCV00398.1 - 0.64 10.5 4.8 4.9 7.7 4.3 2.3 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Mod_r PF07200.13 CCV00398.1 - 1.5 8.9 14.5 2.6 8.2 14.5 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein ALMT PF11744.8 CCV00398.1 - 2.5 6.8 8.2 3.7 6.3 8.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter GTA_holin_3TM PF11351.8 CCV00398.1 - 5.6 7.5 8.6 17 6.0 8.6 1.8 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release SQS_PSY PF00494.19 CCV00399.1 - 2.7e-30 105.8 0.0 4.7e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF1673 PF07895.11 CCV00399.1 - 0.00062 19.5 0.2 0.0011 18.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) TetR_C_24 PF17932.1 CCV00399.1 - 0.047 13.9 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Kri1 PF05178.12 CCV00400.1 - 4.7e-25 88.1 13.7 4.7e-25 88.1 13.7 4.9 5 1 0 5 5 5 1 KRI1-like family Kri1_C PF12936.7 CCV00400.1 - 1.9e-24 85.6 0.1 1.9e-24 85.6 0.1 4.4 4 2 1 5 5 5 1 KRI1-like family C-terminal DRIM PF07539.12 CCV00401.1 - 2.4e-152 508.5 2.2 2.4e-152 508.5 2.2 4.5 5 0 0 5 5 5 1 Down-regulated in metastasis Sigma70_ner PF04546.13 CCV00401.1 - 0.06 13.2 0.4 0.16 11.9 0.4 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Condensin2nSMC PF12422.8 CCV00401.1 - 0.086 13.0 0.4 11 6.1 0.0 3.9 2 1 1 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit FlbT PF07378.11 CCV00401.1 - 0.32 11.1 2.9 2 8.5 0.1 3.5 3 0 0 3 3 3 0 Flagellar protein FlbT ANAPC15 PF15243.6 CCV00401.1 - 3.8 8.0 9.4 9.2 6.7 9.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DNA_pol_phi PF04931.13 CCV00401.1 - 6.3 4.8 9.4 0.99 7.4 3.9 2.3 3 0 0 3 3 3 0 DNA polymerase phi Sel1 PF08238.12 CCV00402.1 - 3.5e-15 56.1 8.8 0.0011 19.6 0.1 6.8 6 0 0 6 6 6 4 Sel1 repeat DUF3528 PF12045.8 CCV00402.1 - 0.019 15.6 0.3 0.052 14.2 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3528) CAMSAP_CC1 PF17095.5 CCV00402.1 - 0.099 12.5 0.3 0.18 11.7 0.3 1.4 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Aconitase PF00330.20 CCV00403.1 - 5.7e-109 365.2 0.2 5.4e-108 361.9 0.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCV00403.1 - 2.4e-21 76.4 0.0 5.3e-21 75.3 0.0 1.6 1 1 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 CCV00403.1 - 0.18 10.5 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) IlvN PF07991.12 CCV00404.1 - 1.7e-44 151.3 0.0 2.4e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 CCV00404.1 - 4.2e-40 137.3 0.0 6.5e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Oxidored_nitro PF00148.19 CCV00404.1 - 0.063 12.0 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Metallophos PF00149.28 CCV00405.1 - 3.7e-12 47.2 0.0 6e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase LSM PF01423.22 CCV00406.1 - 3.5e-10 39.4 0.0 1.3e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 LSM domain WAC_Acf1_DNA_bd PF10537.9 CCV00407.1 - 1e-36 125.5 0.4 2.5e-36 124.2 0.4 1.7 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CCV00407.1 - 1e-24 86.8 0.1 1e-24 86.8 0.1 2.2 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 CCV00407.1 - 2.9e-12 46.7 0.0 5.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 CCV00407.1 - 0.016 14.7 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Nop53 PF07767.11 CCV00407.1 - 0.097 12.0 17.8 0.23 10.8 17.8 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) BLOC1_2 PF10046.9 CCV00407.1 - 0.19 12.1 1.8 0.35 11.2 1.8 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 CCV00407.1 - 4.6 6.6 12.8 1.3 8.3 8.6 2.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Abhydrolase_1 PF00561.20 CCV00408.1 - 9.4e-11 41.8 0.0 5.7e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCV00408.1 - 5.5e-10 38.9 0.9 5.6e-09 35.6 0.9 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCV00408.1 - 5.2e-09 37.0 12.4 7e-09 36.6 12.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CCV00408.1 - 0.0045 16.5 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 CCV00408.1 - 0.029 14.0 0.0 0.12 12.0 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Thioesterase PF00975.20 CCV00408.1 - 0.031 14.4 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 CCV00408.1 - 0.032 13.9 0.1 0.055 13.2 0.1 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 CCV00408.1 - 0.044 13.3 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) MTABC_N PF16185.5 CCV00409.1 - 0.57 9.6 1.2 0.89 9.0 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region Ribosomal_L31e PF01198.19 CCV00410.1 - 4.1e-39 132.7 2.2 5.2e-39 132.4 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e GTP_EFTU PF00009.27 CCV00411.1 - 5e-58 195.8 0.5 8.8e-58 195.0 0.5 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCV00411.1 - 2.5e-29 101.9 0.0 4.9e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCV00411.1 - 2.7e-15 56.5 5.4 8e-15 55.0 5.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCV00411.1 - 1.2e-05 25.3 0.2 5e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCV00411.1 - 0.0055 16.6 0.2 0.018 15.0 0.1 1.9 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 CCV00411.1 - 0.0088 15.6 0.9 0.013 15.1 0.1 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CCV00411.1 - 0.026 14.3 0.2 8.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CCV00411.1 - 0.063 13.8 0.1 1 9.9 0.0 2.6 3 0 0 3 3 3 0 ABC transporter KOW PF00467.29 CCV00412.1 - 4.5e-18 64.5 19.8 3.5e-06 26.8 0.1 7.2 7 0 0 7 7 7 5 KOW motif Spt5_N PF11942.8 CCV00412.1 - 2.3e-17 63.8 13.6 2.3e-17 63.8 13.6 3.0 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 CCV00412.1 - 1.1e-16 60.5 0.0 2.2e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 CCV00412.1 - 7.1e-07 29.7 12.1 7.1e-07 29.7 12.1 4.2 1 1 2 3 3 3 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Cornifin PF02389.15 CCV00412.1 - 2.3 8.4 19.0 1.7 8.8 16.9 1.9 1 1 0 1 1 1 0 Cornifin (SPRR) family CDC45 PF02724.14 CCV00412.1 - 2.4 6.3 23.6 3.7 5.7 23.6 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 CCV00412.1 - 3.9 6.7 33.4 6 6.1 33.4 1.2 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 CCV00412.1 - 6.5 5.2 29.3 9.3 4.7 29.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PP2C PF00481.21 CCV00414.1 - 3.3e-34 118.7 0.0 6.8e-32 111.1 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C RRM_1 PF00076.22 CCV00415.1 - 4.2e-15 55.3 0.0 8.3e-07 28.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCV00415.1 - 1.1e-10 41.5 0.0 1.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif OB_RNB PF08206.11 CCV00415.1 - 0.1 12.3 0.1 0.82 9.4 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain V-ATPase_C PF03223.15 CCV00416.1 - 2.6e-121 405.5 1.1 3e-121 405.3 1.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C APG17 PF04108.12 CCV00416.1 - 0.0091 15.2 0.5 0.6 9.2 0.0 2.5 2 0 0 2 2 2 2 Autophagy protein Apg17 Ribosomal_L31e PF01198.19 CCV00416.1 - 0.082 13.2 0.5 0.19 12.0 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein L31e DUF4279 PF14106.6 CCV00416.1 - 0.18 12.0 1.0 9.4 6.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) DHFR_1 PF00186.19 CCV00417.1 - 2.9e-21 75.9 0.0 5.7e-11 42.4 0.0 2.7 2 1 0 2 2 2 2 Dihydrofolate reductase PTS_2-RNA PF01885.16 CCV00417.1 - 1.1e-17 64.6 0.0 1.8e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family tRNA-synt_1c PF00749.21 CCV00418.1 - 3.1e-105 351.5 0.0 4.6e-105 351.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CCV00418.1 - 1e-33 116.6 0.1 1.7e-33 116.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 CCV00418.1 - 5.1e-05 23.4 0.0 0.0038 17.4 0.0 2.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CCV00418.1 - 0.00014 22.0 0.0 0.00046 20.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCV00418.1 - 0.00018 21.5 0.4 0.00072 19.5 0.4 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MC1 PF05854.11 CCV00418.1 - 0.031 14.5 1.0 0.078 13.3 1.0 1.6 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 LSM PF01423.22 CCV00419.1 - 1e-17 63.6 0.1 1.5e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CCV00419.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Hfq protein TetR_C_23 PF17931.1 CCV00419.1 - 0.068 13.3 0.2 0.089 12.9 0.2 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain adh_short PF00106.25 CCV00420.1 - 2.9e-84 281.4 7.3 1.5e-41 142.0 1.2 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CCV00420.1 - 3.8e-69 232.8 6.3 1.5e-34 119.6 0.7 2.9 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 CCV00420.1 - 2.5e-32 111.0 0.0 5.5e-32 109.9 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 CCV00420.1 - 3.6e-32 111.7 3.9 1.2e-17 64.4 0.3 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 CCV00420.1 - 0.00078 19.6 0.0 0.021 15.0 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.18 CCV00420.1 - 0.0067 16.3 3.6 0.28 11.0 0.3 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CCV00420.1 - 0.015 14.6 0.1 4.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 CCV00420.1 - 0.021 14.0 0.3 0.42 9.7 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PglL_A PF15864.5 CCV00420.1 - 2.7 7.8 8.2 12 5.8 1.1 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase DUF543 PF04418.12 CCV00420.1 - 3.9 7.5 5.1 20 5.3 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF543) NDUFA12 PF05071.16 CCV00421.1 - 7.1e-24 84.5 7.3 8.4e-24 84.2 7.3 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Polysacc_synt_4 PF04669.13 CCV00422.1 - 2.1e-16 60.0 0.7 7.1e-15 55.1 0.7 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Goodbye PF17109.5 CCV00422.1 - 0.026 15.0 0.1 0.041 14.3 0.1 1.4 1 1 0 1 1 1 0 fungal STAND N-terminal Goodbye domain SH3BP5 PF05276.14 CCV00422.1 - 0.029 14.2 0.1 0.034 13.9 0.1 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Asn_synthase PF00733.21 CCV00423.1 - 5e-21 75.8 2.4 7.1e-11 42.4 0.1 3.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CCV00423.1 - 0.00024 21.0 0.0 0.00064 19.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CCV00423.1 - 0.0038 17.4 0.0 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain TMEM70 PF06979.12 CCV00423.1 - 0.087 13.2 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex SNAPc_SNAP43 PF09808.9 CCV00424.1 - 0.099 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 MnmE_helical PF12631.7 CCV00425.1 - 1.8e-31 109.9 0.0 2.9e-31 109.2 0.0 1.3 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 CCV00425.1 - 1.5e-20 73.4 0.0 3e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TrmE_N PF10396.9 CCV00425.1 - 2.2e-19 69.8 0.0 4.9e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus FeoB_N PF02421.18 CCV00425.1 - 8.4e-08 31.9 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CCV00425.1 - 2.8e-05 24.3 0.0 0.00015 21.9 0.0 2.0 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 CCV00425.1 - 0.0075 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 CCV00425.1 - 0.012 15.5 0.0 0.062 13.2 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 CCV00425.1 - 0.032 14.5 0.0 0.077 13.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CCV00425.1 - 0.076 12.7 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 CCV00425.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Ras family DAP3 PF10236.9 CCV00425.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF5102 PF17104.5 CCV00426.1 - 6.3e-53 180.7 0.0 8.3e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) FEZ PF07763.13 CCV00426.1 - 0.0081 15.9 0.1 0.019 14.7 0.1 1.5 2 0 0 2 2 2 1 FEZ-like protein Abhydrolase_6 PF12697.7 CCV00427.1 - 3e-27 96.7 2.8 4.2e-27 96.2 2.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCV00427.1 - 4.9e-13 48.9 0.1 7.1e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCV00427.1 - 1.9e-10 40.8 0.1 3.9e-10 39.8 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CCV00427.1 - 2.4e-07 31.1 0.1 4.1e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 CCV00427.1 - 0.0024 17.7 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.12 CCV00427.1 - 0.025 14.1 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1925 PF09094.11 CCV00427.1 - 0.046 14.0 0.1 0.088 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) LIDHydrolase PF10230.9 CCV00427.1 - 0.047 13.2 0.0 0.59 9.6 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF2974 PF11187.8 CCV00427.1 - 0.055 13.0 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Aldo_ket_red PF00248.21 CCV00428.1 - 1.8e-68 230.9 0.0 2.1e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FTR1 PF03239.14 CCV00430.1 - 9.2e-55 186.0 6.2 6e-35 120.9 1.6 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family Cyt_bd_oxida_II PF02322.15 CCV00430.1 - 8.2e-05 22.1 2.3 8.2e-05 22.1 2.3 2.0 2 1 0 2 2 2 1 Cytochrome bd terminal oxidase subunit II Herpes_glycop PF01528.16 CCV00430.1 - 0.0069 15.3 0.2 0.027 13.3 0.0 1.8 2 0 0 2 2 2 1 Herpesvirus glycoprotein M Wzy_C PF04932.15 CCV00430.1 - 0.034 13.8 0.1 0.034 13.8 0.1 3.5 3 1 0 3 3 3 0 O-Antigen ligase BaxI_1 PF12811.7 CCV00430.1 - 0.097 12.2 3.3 1.3 8.6 0.5 2.4 2 0 0 2 2 2 0 Bax inhibitor 1 like DUF3341 PF11821.8 CCV00430.1 - 2.2 7.9 6.9 1.1 8.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) Phage_holin_3_6 PF07332.11 CCV00430.1 - 3.6 7.7 14.6 0.043 13.9 1.3 3.2 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3180 PF11377.8 CCV00430.1 - 4 7.6 12.6 0.35 11.0 1.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) DUF3021 PF11457.8 CCV00430.1 - 4.2 7.7 12.5 2 8.7 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) FtsX PF02687.21 CCV00430.1 - 5.8 7.5 16.2 1.5 9.3 1.8 3.6 3 0 0 3 3 3 0 FtsX-like permease family DUF4191 PF13829.6 CCV00430.1 - 6.9 5.9 6.0 18 4.6 0.4 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4191) Cu-oxidase_2 PF07731.14 CCV00431.1 - 8.9e-41 138.8 1.7 3.7e-36 123.9 0.0 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 CCV00431.1 - 6e-35 120.7 0.0 1.2e-32 113.3 0.0 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CCV00431.1 - 1.3e-27 96.1 0.4 1.4e-24 86.3 0.2 3.7 3 1 0 3 3 3 2 Multicopper oxidase Phosphoesterase PF04185.14 CCV00432.1 - 1.1e-82 278.0 0.6 1.1e-82 278.0 0.6 1.4 2 0 0 2 2 2 1 Phosphoesterase family Fascin PF06268.13 CCV00432.1 - 0.067 13.4 0.2 0.3 11.3 0.1 2.2 2 0 0 2 2 2 0 Fascin domain His_Phos_2 PF00328.22 CCV00433.1 - 2.3e-41 142.4 0.0 3.1e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Thi4 PF01946.17 CCV00434.1 - 4.5e-96 320.6 0.0 5.4e-96 320.4 0.0 1.1 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 CCV00434.1 - 1.5e-07 31.5 0.2 4.8e-07 29.9 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CCV00434.1 - 2.4e-06 27.4 2.4 4e-06 26.6 2.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CCV00434.1 - 2.8e-05 23.3 0.3 5e-05 22.5 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CCV00434.1 - 3.5e-05 23.2 0.2 4.2e-05 22.9 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CCV00434.1 - 4e-05 23.6 0.4 0.0019 18.2 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CCV00434.1 - 7.3e-05 22.0 0.5 0.00014 21.1 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 CCV00434.1 - 0.00035 19.4 0.3 0.00047 19.0 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 CCV00434.1 - 0.011 15.1 0.5 0.021 14.1 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCV00434.1 - 0.048 12.7 0.0 0.18 10.9 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 CCV00434.1 - 0.17 10.7 0.2 0.25 10.1 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Transp_cyt_pur PF02133.15 CCV00435.1 - 2.6e-12 46.3 28.9 3.8e-12 45.7 28.9 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4191 PF13829.6 CCV00435.1 - 0.2 11.0 5.0 3 7.1 3.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) SH3_9 PF14604.6 CCV00437.1 - 1.3e-36 124.2 6.7 6.3e-15 54.8 0.3 3.8 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.28 CCV00437.1 - 7.7e-35 118.3 1.5 7.1e-14 51.1 0.2 4.1 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 CCV00437.1 - 7.6e-25 86.5 0.0 1.8e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 CCV00437.1 - 8.9e-17 60.5 0.0 1.3e-07 31.1 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SAM_4 PF18017.1 CCV00437.1 - 0.0045 16.9 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 CCV00437.1 - 0.0058 16.7 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 SH3 domain Ribosomal_L28e PF01778.17 CCV00439.1 - 6.6e-37 126.8 0.5 6.6e-37 126.8 0.5 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CCV00439.1 - 1.6e-28 99.2 12.1 1.6e-28 99.2 12.1 2.6 3 0 0 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.10 CCV00439.1 - 0.00045 19.7 13.1 0.00057 19.3 13.1 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 CCV00439.1 - 0.0072 16.1 0.6 0.011 15.4 0.6 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Pkinase_Tyr PF07714.17 CCV00440.1 - 1.6e-46 158.7 0.0 1.9e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CCV00440.1 - 3.2e-43 148.0 0.0 4.2e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CCV00440.1 - 0.00069 19.6 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Nitroreductase PF00881.24 CCV00441.1 - 6e-31 107.8 0.1 2.9e-14 53.5 0.0 2.1 2 0 0 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 CCV00441.1 - 0.017 14.7 0.0 7 6.1 0.0 2.6 3 0 0 3 3 3 0 Putative TM nitroreductase GGDEF_2 PF17853.1 CCV00441.1 - 0.02 15.2 0.2 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 GGDEF-like domain Glyco_tran_10_N PF17039.5 CCV00441.1 - 0.055 13.9 0.0 0.73 10.3 0.0 2.4 2 0 0 2 2 2 0 Fucosyltransferase, N-terminal PRP4 PF08799.11 CCV00442.1 - 4e-11 42.3 0.1 6.9e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like COX6B PF02297.17 CCV00443.1 - 2.8e-13 49.9 4.1 3.4e-13 49.6 4.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DUF1356 PF07092.12 CCV00445.1 - 0.0042 16.4 0.6 0.0063 15.8 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Cation_ATPase_C PF00689.21 CCV00445.1 - 0.02 14.6 0.6 0.031 14.0 0.6 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus LEA_2 PF03168.13 CCV00445.1 - 0.086 13.4 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein Sarcoglycan_1 PF04790.13 CCV00445.1 - 0.16 11.3 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Cpn60_TCP1 PF00118.24 CCV00446.1 - 8.2e-152 506.3 12.1 1e-151 506.0 12.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_14 PF13173.6 CCV00446.1 - 0.029 14.4 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain UFD1 PF03152.14 CCV00447.1 - 9e-30 103.4 0.0 3.6e-29 101.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.18 CCV00447.1 - 0.15 12.2 0.0 7 6.9 0.0 2.2 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain RraA-like PF03737.15 CCV00448.1 - 2.6e-36 125.1 0.0 3.3e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA ATPgrasp_N PF18130.1 CCV00448.1 - 0.12 13.0 0.1 2.7 8.6 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp N-terminal domain DUF3808 PF10300.9 CCV00449.1 - 9.1e-82 275.3 0.8 1.5e-81 274.6 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.20 CCV00449.1 - 1.7e-35 122.1 0.0 2.9e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CCV00449.1 - 3e-12 46.9 0.0 9.4e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCV00449.1 - 5.3e-09 36.1 0.0 1.8e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TPR_8 PF13181.6 CCV00449.1 - 2.1e-05 24.3 0.3 2.6 8.5 0.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCV00449.1 - 0.015 15.9 11.7 0.67 10.7 0.1 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat CRA_rpt PF07046.11 CCV00449.1 - 0.062 13.5 6.3 0.25 11.5 6.3 2.1 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat TPR_2 PF07719.17 CCV00449.1 - 0.082 13.1 0.3 0.082 13.1 0.3 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCV00449.1 - 0.1 12.5 11.6 3.6 7.6 0.4 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CCV00449.1 - 0.68 10.4 4.0 2.1 8.9 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 CCV00449.1 - 0.71 10.7 8.1 0.064 13.9 1.6 2.8 2 0 0 2 2 1 0 Tetratricopeptide repeat MCLC PF05934.11 CCV00449.1 - 7 5.3 7.9 15 4.2 7.9 1.5 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) TPR_16 PF13432.6 CCV00449.1 - 8.9 7.1 13.6 0.34 11.6 0.7 4.4 3 1 0 3 3 3 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 CCV00450.1 - 0.59 10.7 4.1 1.7 9.3 4.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type GAF PF01590.26 CCV00451.1 - 0.00048 20.8 0.1 0.00058 20.5 0.1 1.3 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 CCV00451.1 - 0.066 13.5 0.2 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 GAF domain Abhydrolase_1 PF00561.20 CCV00452.1 - 8.7e-41 140.3 0.0 6.4e-40 137.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 CCV00452.1 - 0.0005 19.8 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 CCV00452.1 - 0.14 11.4 0.0 1.8 7.7 0.1 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 tRNA-synt_His PF13393.6 CCV00453.1 - 9.6e-41 140.0 4.2 1.2e-40 139.8 0.2 2.4 2 1 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CCV00453.1 - 2.1e-09 37.4 0.0 4.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 CCV00453.1 - 1.1e-05 25.1 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs WHEP-TRS PF00458.20 CCV00453.1 - 0.038 14.2 0.4 0.15 12.2 0.4 2.1 1 0 0 1 1 1 0 WHEP-TRS domain tRNA-synt_2 PF00152.20 CCV00453.1 - 0.23 10.5 2.3 3.1 6.8 0.7 2.8 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) Use1 PF09753.9 CCV00454.1 - 2.1e-10 40.8 0.0 3.9e-10 39.9 0.0 1.5 2 0 0 2 2 2 1 Membrane fusion protein Use1 DUF2236 PF09995.9 CCV00454.1 - 0.054 13.7 8.9 0.65 10.2 9.5 2.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) DUF1192 PF06698.11 CCV00454.1 - 7 6.8 9.0 12 6.0 1.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Ribonuc_L-PSP PF01042.21 CCV00455.1 - 5e-37 126.6 0.4 8.9e-37 125.8 0.4 1.4 1 1 0 1 1 1 1 Endoribonuclease L-PSP RhoGEF PF00621.20 CCV00456.1 - 4.1e-14 53.2 0.0 1.5e-13 51.4 0.0 1.9 1 1 0 1 1 1 1 RhoGEF domain Ras PF00071.22 CCV00458.1 - 6.7e-59 198.1 0.1 8.7e-59 197.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCV00458.1 - 5.6e-37 126.6 0.1 8e-37 126.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCV00458.1 - 6.6e-16 58.3 0.1 7.9e-16 58.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCV00458.1 - 8.3e-06 25.5 0.1 0.00012 21.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CCV00458.1 - 0.00011 22.2 0.0 0.00018 21.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CCV00458.1 - 0.00015 21.3 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CCV00458.1 - 0.00039 19.9 0.1 0.00049 19.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CCV00458.1 - 0.0054 16.7 0.2 2.3 8.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Seipin PF06775.14 CCV00459.1 - 7.3e-41 140.4 0.1 1.2e-40 139.8 0.1 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Claudin_2 PF13903.6 CCV00459.1 - 0.0088 15.8 1.1 0.0088 15.8 1.1 2.3 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF2204 PF09970.9 CCV00459.1 - 0.23 11.1 0.0 0.39 10.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) TAP42 PF04177.12 CCV00460.1 - 2.2e-58 197.9 0.0 2.5e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family DAGK_cat PF00781.24 CCV00461.1 - 9.4e-26 89.9 0.0 3.3e-25 88.1 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Thioredoxin PF00085.20 CCV00462.1 - 2.7e-52 175.0 0.1 2.2e-26 91.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 CCV00462.1 - 4.8e-23 81.9 0.4 1.5e-22 80.3 0.1 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 CCV00462.1 - 5.1e-18 65.5 0.3 5.2e-11 42.4 0.0 2.5 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CCV00462.1 - 9.9e-11 42.1 0.1 0.00018 22.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CCV00462.1 - 3.3e-08 33.6 0.1 0.011 15.9 0.1 2.7 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 CCV00462.1 - 6.8e-08 32.5 0.1 0.0019 18.1 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 CCV00462.1 - 3.1e-07 30.6 0.1 0.026 14.8 0.0 3.8 2 2 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 CCV00462.1 - 0.00018 21.3 0.1 0.067 12.9 0.0 2.5 2 0 0 2 2 2 2 Redoxin TraF PF13728.6 CCV00462.1 - 0.00025 20.9 0.0 0.42 10.4 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein HyaE PF07449.11 CCV00462.1 - 0.0088 16.0 0.0 2.3 8.2 0.0 3.0 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE DDE_Tnp_1_2 PF13586.6 CCV00462.1 - 0.015 15.6 0.0 1.4 9.3 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain Thioredoxin_4 PF13462.6 CCV00462.1 - 0.061 13.5 0.2 0.45 10.6 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_6 PF13848.6 CCV00462.1 - 0.075 12.9 0.1 1.6 8.6 0.1 2.7 1 1 0 1 1 1 0 Thioredoxin-like domain TetR_C_14 PF17754.1 CCV00462.1 - 0.1 12.5 5.4 0.21 11.5 0.3 2.6 3 0 0 3 3 3 0 MftR C-terminal domain DUF1391 PF07151.12 CCV00462.1 - 0.17 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) Amidohydro_1 PF01979.20 CCV00463.1 - 1.8e-64 218.3 0.5 2.8e-64 217.6 0.5 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 CCV00463.1 - 9.4e-55 184.1 0.6 1.8e-54 183.2 0.6 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 CCV00463.1 - 1e-34 118.7 0.2 3.3e-34 117.1 0.1 2.0 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.20 CCV00463.1 - 1.6e-28 98.6 0.0 3.6e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 CCV00463.1 - 6.3e-08 32.5 0.9 5.9e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family AhpC-TSA PF00578.21 CCV00464.1 - 5.7e-26 90.9 0.0 7e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCV00464.1 - 6.5e-16 58.4 0.0 8.7e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 CCV00464.1 - 0.059 13.5 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DEAD PF00270.29 CCV00465.1 - 5.3e-28 98.0 0.1 1.6e-27 96.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase UEV PF05743.13 CCV00465.1 - 3.3e-17 62.5 1.6 1.4e-15 57.2 0.4 2.3 1 1 1 2 2 2 1 UEV domain ResIII PF04851.15 CCV00465.1 - 5.9e-06 26.4 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCV00465.1 - 0.00012 22.3 0.0 0.00062 20.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Vps23_core PF09454.10 CCV00465.1 - 0.0032 17.4 0.7 0.011 15.7 0.4 2.1 2 0 0 2 2 2 1 Vps23 core domain AAA_22 PF13401.6 CCV00465.1 - 0.071 13.4 2.6 0.35 11.2 0.2 3.1 2 1 1 3 3 3 0 AAA domain VWA_3 PF13768.6 CCV00465.1 - 0.11 12.5 0.2 0.52 10.2 0.0 2.2 3 0 0 3 3 3 0 von Willebrand factor type A domain MscS_porin PF12795.7 CCV00465.1 - 0.15 11.6 2.4 0.31 10.5 2.4 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DHHA2 PF02833.14 CCV00466.1 - 3.4e-30 105.1 0.0 5.3e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 CCV00466.1 - 2.3e-10 40.6 0.0 3.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 DHH family Y_phosphatase2 PF03162.13 CCV00467.1 - 4.7e-40 136.9 0.0 5.3e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CCV00467.1 - 0.00027 21.0 0.0 0.00056 20.0 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CCV00467.1 - 0.056 13.3 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF155 PF02582.14 CCV00468.1 - 2.3e-47 161.4 0.0 3.4e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 CCV00468.1 - 0.029 14.8 0.0 0.074 13.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Vps54 PF07928.12 CCV00469.1 - 7.1e-46 156.0 0.2 2.3e-45 154.3 0.2 1.9 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 CCV00469.1 - 6.9e-06 25.6 0.5 1.1e-05 24.9 0.5 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex ATP_bind_1 PF03029.17 CCV00469.1 - 0.1 12.3 1.9 8.6 6.1 0.4 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RCC1 PF00415.18 CCV00470.1 - 7.2e-13 49.0 4.7 0.0021 18.6 0.0 5.4 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 CCV00470.1 - 2.7e-10 40.6 1.2 1.1e-09 38.6 1.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCV00470.1 - 6.2e-08 33.1 0.0 1.3e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCV00470.1 - 2.1e-07 31.1 1.5 8e-05 22.8 0.4 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCV00470.1 - 1.2e-06 28.4 2.2 0.056 14.0 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CCV00470.1 - 2e-05 24.8 2.7 0.054 14.0 0.2 3.2 2 0 0 2 2 2 2 Ankyrin repeat CRIC_ras_sig PF10534.9 CCV00471.1 - 0.15 12.3 0.1 0.5 10.6 0.1 1.9 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras YchF-GTPase_C PF06071.13 CCV00472.1 - 2.1e-33 114.3 0.0 5.4e-33 113.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CCV00472.1 - 9.3e-18 64.4 0.0 2e-17 63.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCV00472.1 - 1.5e-06 27.9 0.0 2.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 CCV00472.1 - 0.0092 16.5 0.8 3 8.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain BetaGal_dom3 PF13363.6 CCV00472.1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 ABC_tran PF00005.27 CCV00472.1 - 0.31 11.5 1.1 1.4 9.4 0.1 2.1 2 0 0 2 2 2 0 ABC transporter RNase_HII PF01351.18 CCV00473.1 - 2.9e-44 151.3 0.0 1e-38 133.2 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease HII DNA_pol_A_exo1 PF01612.20 CCV00474.1 - 1.9e-33 115.7 0.2 2.6e-33 115.2 0.2 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CCV00474.1 - 6.1e-16 58.9 0.0 1.8e-15 57.4 0.0 1.9 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 CCV00474.1 - 7.4e-10 38.7 0.2 1.6e-09 37.6 0.2 1.6 1 0 0 1 1 1 1 HRDC domain Cellulase PF00150.18 CCV00475.1 - 7.8e-10 38.6 0.1 1.7e-09 37.6 0.1 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RskA PF10099.9 CCV00475.1 - 0.0016 18.8 0.8 0.0031 17.8 0.8 1.5 1 0 0 1 1 1 1 Anti-sigma-K factor rskA PBP1_TM PF14812.6 CCV00475.1 - 0.024 15.0 0.0 0.36 11.2 0.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Phage_holin_3_6 PF07332.11 CCV00475.1 - 0.1 12.6 1.1 0.2 11.7 1.1 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Harakiri PF15196.6 CCV00475.1 - 1.5 9.4 8.6 0.73 10.3 4.3 2.2 1 1 1 2 2 2 0 Activator of apoptosis harakiri DEAD PF00270.29 CCV00476.1 - 1e-44 152.4 0.1 1.9e-44 151.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCV00476.1 - 9e-33 112.9 0.3 3.9e-32 110.9 0.1 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 CCV00476.1 - 8.5e-05 22.9 0.1 0.0061 16.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CCV00476.1 - 0.00023 21.2 0.0 0.00055 20.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCV00476.1 - 0.00093 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 CCV00476.1 - 0.012 14.4 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF3449 PF11931.8 CCV00477.1 - 6.5e-69 231.4 0.5 2.1e-68 229.7 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 CCV00477.1 - 2.8e-23 82.2 0.5 3.1e-22 78.9 0.2 2.4 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_jaz PF12171.8 CCV00477.1 - 1e-06 28.8 6.0 2.7e-05 24.3 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCV00477.1 - 3.5e-06 27.2 3.9 0.00021 21.6 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.8 CCV00477.1 - 0.0031 17.3 0.4 0.0064 16.4 0.4 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_2 PF12756.7 CCV00477.1 - 0.0079 16.5 0.0 6.2 7.2 0.0 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) RPAP1_N PF08621.10 CCV00477.1 - 0.048 13.4 2.8 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 RPAP1-like, N-terminal Sugar_tr PF00083.24 CCV00479.1 - 8.2e-41 140.3 63.2 2.1e-15 56.6 9.9 4.1 2 2 2 4 4 4 4 Sugar (and other) transporter MFS_1 PF07690.16 CCV00479.1 - 1.2e-39 136.3 70.3 6.1e-11 41.8 17.5 4.2 2 2 2 4 4 4 4 Major Facilitator Superfamily Gal_mutarotas_2 PF13802.6 CCV00479.1 - 0.02 15.2 0.2 13 6.2 0.0 2.8 2 0 0 2 2 2 0 Galactose mutarotase-like Coiled-coil_56 PF09813.9 CCV00479.1 - 0.14 12.3 0.9 21 5.2 0.1 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Gp5_OB PF06714.11 CCV00479.1 - 0.74 10.0 2.0 7.9 6.7 0.2 2.4 2 0 0 2 2 2 0 Gp5 N-terminal OB domain AAA_16 PF13191.6 CCV00480.1 - 1.7e-10 41.5 10.8 3.3e-10 40.6 0.1 3.8 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 CCV00480.1 - 3.6e-09 37.0 0.0 1.4e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CCV00480.1 - 8.7e-07 29.4 0.0 2.3e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CCV00480.1 - 0.0027 17.5 0.0 0.0071 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 CCV00480.1 - 0.0086 16.2 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA lid domain AAA_33 PF13671.6 CCV00480.1 - 0.018 15.2 0.1 0.38 10.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain Cdc6_C PF09079.11 CCV00480.1 - 0.05 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain AAA_5 PF07728.14 CCV00480.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CCV00480.1 - 0.085 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.14 CCV00480.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 CCV00480.1 - 0.096 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 CCV00480.1 - 0.097 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 CCV00480.1 - 0.13 12.6 0.1 0.59 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain zf-CCHC PF00098.23 CCV00481.1 - 1e-05 25.4 39.6 0.0019 18.2 1.7 5.7 5 1 1 6 6 6 4 Zinc knuckle zf-CCHC_4 PF14392.6 CCV00481.1 - 0.025 14.3 28.6 0.41 10.4 0.3 5.1 4 1 1 5 5 5 0 Zinc knuckle TPP_enzyme_N PF02776.18 CCV00482.1 - 3.9e-34 117.7 0.1 3.3e-33 114.7 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCV00482.1 - 9.6e-20 70.7 0.0 2.2e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCV00482.1 - 1.5e-13 50.8 0.0 4.2e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CN_hydrolase PF00795.22 CCV00483.1 - 2.1e-18 66.6 0.0 1.5e-17 63.8 0.0 1.9 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase ATPgrasp_N PF18130.1 CCV00483.1 - 0.058 14.0 0.0 0.15 12.6 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp N-terminal domain LEA_2 PF03168.13 CCV00484.1 - 0.0056 17.2 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 Late embryogenesis abundant protein YL1_C PF08265.11 CCV00485.1 - 2.6e-15 55.9 0.4 4.2e-15 55.2 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Phostensin PF13914.6 CCV00485.1 - 0.15 12.7 0.7 0.46 11.1 0.6 1.8 1 1 1 2 2 2 0 Phostensin PP1-binding and SH3-binding region CM_2 PF01817.21 CCV00487.1 - 0.0043 17.4 0.0 0.05 13.9 0.0 2.4 2 1 0 2 2 2 1 Chorismate mutase type II Kinesin PF00225.23 CCV00488.1 - 4.6e-112 374.2 0.4 8.7e-112 373.3 0.4 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CCV00488.1 - 1.7e-26 92.9 0.5 4.5e-26 91.6 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Ribosomal_60s PF00428.19 CCV00488.1 - 0.22 12.1 8.1 0.21 12.2 4.5 2.8 2 1 1 3 3 3 0 60s Acidic ribosomal protein Filo_VP35 PF02097.15 CCV00488.1 - 0.46 9.5 3.5 2.5 7.1 0.3 2.4 2 0 0 2 2 2 0 Filoviridae VP35 LPP PF04728.13 CCV00488.1 - 2.7 8.4 8.2 0.38 11.2 1.7 3.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 CCV00488.1 - 2.9 8.4 14.1 0.5 10.8 0.3 5.6 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) OMPdecase PF00215.24 CCV00489.1 - 3.9e-70 235.9 0.0 6.1e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family HhH-GPD PF00730.25 CCV00489.1 - 4.9e-17 62.3 0.0 1.2e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CCV00489.1 - 7.4e-08 31.9 0.0 6.6e-07 28.9 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif LRR_8 PF13855.6 CCV00490.1 - 6e-25 86.8 29.5 1.8e-10 40.4 4.1 3.8 1 1 4 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CCV00490.1 - 1.3e-12 47.7 15.0 2.3e-05 24.6 2.6 5.0 3 1 5 8 8 8 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CCV00490.1 - 2.8e-08 33.4 0.0 0.00012 21.6 0.0 2.7 2 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 CCV00490.1 - 5.5e-06 26.2 6.6 6.8 7.7 0.1 6.7 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 CCV00490.1 - 0.35 11.1 17.8 3.4 7.9 0.1 7.2 8 0 0 8 8 8 0 Leucine Rich repeat Alg6_Alg8 PF03155.15 CCV00491.1 - 7.9e-139 463.7 27.3 9.1e-139 463.5 27.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family SGS PF05002.15 CCV00492.1 - 3.4e-30 104.0 0.0 5.1e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 SGS domain HlyD_3 PF13437.6 CCV00492.1 - 0.057 14.1 0.1 0.24 12.1 0.1 1.9 1 1 1 2 2 2 0 HlyD family secretion protein DUF2057 PF09829.9 CCV00492.1 - 0.096 12.8 0.3 0.15 12.2 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Aconitase PF00330.20 CCV00493.1 - 5.6e-144 480.6 0.0 7.2e-144 480.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCV00493.1 - 2.2e-30 105.6 0.0 5.6e-30 104.4 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain MRP-L28 PF09812.9 CCV00493.1 - 0.15 12.2 3.0 0.93 9.6 0.8 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 ABC_membrane PF00664.23 CCV00494.1 - 2.4e-71 240.6 22.1 1.1e-35 123.6 4.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCV00494.1 - 1e-47 162.1 0.0 8.5e-30 104.1 0.0 2.8 2 1 0 2 2 2 2 ABC transporter IstB_IS21 PF01695.17 CCV00494.1 - 5.3e-05 23.0 0.2 1.5 8.5 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein SMC_N PF02463.19 CCV00494.1 - 0.00028 20.4 0.0 0.45 9.9 0.0 3.4 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CCV00494.1 - 0.00046 20.2 0.3 0.91 9.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase MeaB PF03308.16 CCV00494.1 - 0.0014 17.7 0.1 1.6 7.6 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 CCV00494.1 - 0.0024 17.8 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CCV00494.1 - 0.003 18.0 5.3 0.21 11.9 0.7 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 CCV00494.1 - 0.0039 16.9 0.2 2 8.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 CCV00494.1 - 0.0082 15.7 0.3 0.79 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 CCV00494.1 - 0.056 13.5 1.4 2.3 8.2 0.2 2.4 2 0 0 2 2 2 0 Dynamin family Gly_transf_sug PF04488.15 CCV00495.1 - 2.5e-21 76.1 0.0 4.5e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 CCV00495.1 - 0.24 10.8 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 CCV00495.1 - 0.38 10.0 0.2 0.56 9.4 0.2 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain AAA PF00004.29 CCV00496.1 - 1.3e-57 193.9 0.0 1.9e-43 148.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CCV00496.1 - 3.7e-19 68.9 0.2 8e-19 67.8 0.2 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 CCV00496.1 - 4e-14 52.1 4.4 2.1e-11 43.4 0.5 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CCV00496.1 - 2e-10 41.3 10.6 7.1e-05 23.2 0.1 4.7 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 CCV00496.1 - 4.9e-08 33.4 0.8 0.0057 16.9 0.1 4.4 2 2 1 3 3 3 2 AAA domain AAA_18 PF13238.6 CCV00496.1 - 8.6e-08 32.8 0.0 0.0032 18.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CCV00496.1 - 4.1e-07 30.0 0.1 0.028 14.4 0.0 3.2 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 CCV00496.1 - 1.2e-06 28.4 0.1 0.0048 16.7 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CCV00496.1 - 1.4e-06 28.5 0.0 0.036 14.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CCV00496.1 - 5e-06 26.4 0.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 CCV00496.1 - 6.5e-06 25.6 0.1 0.051 12.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_25 PF13481.6 CCV00496.1 - 1.6e-05 24.6 15.3 0.0094 15.5 0.9 4.7 3 2 2 5 5 4 2 AAA domain Mg_chelatase PF01078.21 CCV00496.1 - 2.6e-05 23.7 0.7 0.086 12.2 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCV00496.1 - 3.8e-05 23.7 0.1 0.77 9.8 0.0 3.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CCV00496.1 - 7.4e-05 22.7 0.0 0.48 10.3 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain RNA_helicase PF00910.22 CCV00496.1 - 8.3e-05 22.9 0.0 0.52 10.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase APS_kinase PF01583.20 CCV00496.1 - 0.00011 22.1 0.0 0.012 15.5 0.0 3.1 2 1 1 3 3 3 1 Adenylylsulphate kinase AAA_24 PF13479.6 CCV00496.1 - 0.00012 21.9 0.0 0.033 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CCV00496.1 - 0.00012 22.0 1.4 0.55 10.1 0.1 3.9 3 1 0 3 3 3 1 NACHT domain AAA_2 PF07724.14 CCV00496.1 - 0.00013 22.2 0.0 0.027 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 CCV00496.1 - 0.00021 21.3 0.0 0.39 10.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 CCV00496.1 - 0.00028 21.3 0.4 0.26 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CCV00496.1 - 0.00071 19.3 0.0 0.12 12.1 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 CCV00496.1 - 0.00078 20.0 0.0 0.15 12.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 CCV00496.1 - 0.0011 19.2 0.0 0.71 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCV00496.1 - 0.0017 18.1 0.1 0.03 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CCV00496.1 - 0.0023 17.3 0.2 0.77 9.0 0.1 2.5 2 0 0 2 2 2 1 Zeta toxin SKI PF01202.22 CCV00496.1 - 0.0025 18.0 0.1 3.2 7.8 0.0 2.9 3 0 0 3 3 3 1 Shikimate kinase AAA_29 PF13555.6 CCV00496.1 - 0.0026 17.5 0.1 0.038 13.7 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain Bac_DnaA PF00308.18 CCV00496.1 - 0.0032 17.4 0.0 0.75 9.6 0.0 2.8 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_19 PF13245.6 CCV00496.1 - 0.0061 16.9 0.1 0.3 11.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 CCV00496.1 - 0.0066 15.7 0.1 3.2 6.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Cytidylate_kin PF02224.18 CCV00496.1 - 0.0091 15.8 0.0 0.032 14.0 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase Sigma54_activ_2 PF14532.6 CCV00496.1 - 0.0091 16.1 0.0 2.7 8.1 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 CCV00496.1 - 0.011 15.2 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CCV00496.1 - 0.013 15.4 0.1 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 CCV00496.1 - 0.026 14.4 0.0 2.2 8.1 0.0 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Cytidylate_kin2 PF13189.6 CCV00496.1 - 0.046 13.8 0.0 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_23 PF13476.6 CCV00496.1 - 0.063 13.8 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CCV00496.1 - 0.063 12.4 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) T2SSE PF00437.20 CCV00496.1 - 0.064 12.3 0.0 0.68 8.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 CCV00496.1 - 0.064 12.6 0.2 9.8 5.4 0.0 2.3 2 0 0 2 2 2 0 KaiC Viral_helicase1 PF01443.18 CCV00496.1 - 0.095 12.4 0.0 0.6 9.8 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 CCV00496.1 - 0.098 12.5 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 CCV00496.1 - 0.12 12.1 0.1 0.5 10.1 0.0 2.0 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.16 CCV00496.1 - 0.13 11.7 0.0 17 4.8 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 CCV00496.1 - 0.21 10.8 0.0 6.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Ofd1_CTDD PF10637.9 CCV00497.1 - 5.8e-79 265.1 0.0 4.3e-74 249.1 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 CCV00497.1 - 4.4e-28 97.8 0.0 8.7e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CCV00497.1 - 1.6e-12 48.1 0.2 3.8e-12 46.9 0.2 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RNA_pol_3_Rpc31 PF11705.8 CCV00497.1 - 0.037 14.3 5.8 0.076 13.3 5.8 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 CCV00497.1 - 0.95 9.9 8.1 3.7 8.0 8.1 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FYDLN_acid PF09538.10 CCV00497.1 - 1.1 10.0 8.7 4.1 8.1 8.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TRM PF02005.16 CCV00498.1 - 4.3e-103 345.4 0.0 6.8e-77 259.2 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Ribosomal_L14 PF00238.19 CCV00499.1 - 1e-42 145.1 0.7 1.1e-42 144.9 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e His_Phos_1 PF00300.22 CCV00500.1 - 2e-14 53.7 1.7 3.1e-14 53.1 0.3 2.0 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DnaJ_C PF01556.18 CCV00501.1 - 1.7e-41 141.7 0.7 2.2e-41 141.4 0.7 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCV00501.1 - 1.7e-20 72.9 0.1 3.3e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCV00501.1 - 6.6e-17 61.6 19.3 1.1e-16 61.0 19.3 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CCV00501.1 - 0.0022 17.9 8.2 0.033 14.1 0.9 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 CCV00501.1 - 0.36 10.5 8.3 0.56 9.8 1.8 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 HypA PF01155.19 CCV00501.1 - 0.57 10.2 12.0 2.5 8.2 3.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrom_CIII PF02085.16 CCV00501.1 - 1.7 9.0 7.6 4.3 7.7 7.5 1.7 1 1 0 1 1 1 0 Class III cytochrome C family Cytochrome_C7 PF14522.6 CCV00501.1 - 5 7.2 11.7 0.81 9.7 2.0 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zinc-ribbons_6 PF07191.12 CCV00501.1 - 8.7 6.4 11.2 7.1 6.7 3.3 2.2 1 1 1 2 2 2 0 zinc-ribbons DUF21 PF01595.20 CCV00502.1 - 1e-36 126.3 0.1 1.5e-36 125.7 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CCV00502.1 - 0.022 15.2 0.1 3.3 8.2 0.0 3.2 3 0 0 3 3 3 0 CBS domain CoA_trans PF01144.23 CCV00503.1 - 2.4e-193 638.4 8.6 6.8e-63 212.0 0.3 4.0 4 0 0 4 4 4 4 Coenzyme A transferase Mal_decarbox_Al PF16957.5 CCV00503.1 - 9.4e-05 20.9 1.1 0.03 12.7 0.0 2.7 3 0 0 3 3 3 2 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 CCV00503.1 - 0.00021 21.2 0.3 0.39 10.6 0.0 2.4 2 0 0 2 2 2 2 Acetyl-CoA hydrolase/transferase C-terminal domain DeoRC PF00455.22 CCV00503.1 - 0.019 14.9 0.0 33 4.4 0.0 3.8 3 0 0 3 3 3 0 DeoR C terminal sensor domain RabGAP-TBC PF00566.18 CCV00504.1 - 1.3e-29 103.4 4.5 1.4e-28 100.1 0.9 2.3 1 1 1 2 2 2 2 Rab-GTPase-TBC domain Ribosomal_S21e PF01249.18 CCV00505.1 - 5.5e-35 119.3 0.1 6.1e-35 119.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e UTP15_C PF09384.10 CCV00506.1 - 4.2e-44 149.8 0.0 6.4e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CCV00506.1 - 6.7e-22 77.4 1.1 1.3e-05 25.9 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCV00506.1 - 1.1e-05 25.6 0.0 0.028 14.7 0.0 3.8 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CCV00506.1 - 0.00075 18.1 0.1 0.0024 16.5 0.0 1.7 1 1 1 2 2 2 1 Cytochrome D1 heme domain SKN1 PF03935.15 CCV00507.1 - 5.6e-177 589.1 6.3 6.8e-177 588.9 6.3 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Adaptin_N PF01602.20 CCV00507.1 - 4.4e-37 127.8 2.2 5.8e-37 127.4 2.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 CCV00507.1 - 0.18 12.2 0.1 11 6.5 0.1 2.3 1 1 1 2 2 2 0 HEAT repeats HLH PF00010.26 CCV00508.1 - 6.2e-06 26.1 1.8 6.2e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PALP PF00291.25 CCV00509.1 - 7.6e-56 189.7 0.3 1e-55 189.2 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-RING_4 PF14570.6 CCV00511.1 - 5.9e-23 80.4 11.8 1e-22 79.7 11.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CCV00511.1 - 1.7e-07 31.0 10.0 3e-07 30.2 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCV00511.1 - 6e-06 26.0 10.1 5.1e-05 23.0 5.2 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CCV00511.1 - 0.00012 22.3 12.2 0.00024 21.4 12.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-UDP PF14569.6 CCV00511.1 - 0.0037 17.4 4.1 0.0065 16.6 4.1 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 CCV00511.1 - 0.011 15.5 11.5 0.026 14.3 11.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCV00511.1 - 0.014 15.2 11.9 0.028 14.3 11.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 CCV00511.1 - 0.034 14.1 5.7 0.034 14.1 5.7 1.6 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.6 CCV00511.1 - 0.066 13.3 8.1 0.21 11.6 7.0 2.2 1 1 1 2 2 2 0 RING-type zinc-finger DAO PF01266.24 CCV00514.1 - 1.6e-45 156.2 9.0 1.9e-45 156.0 9.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCV00514.1 - 1.3e-05 25.3 0.1 1.3e-05 25.3 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CCV00514.1 - 0.0064 15.8 0.1 0.036 13.3 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.15 CCV00514.1 - 0.012 14.2 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 CCV00514.1 - 0.05 12.8 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCV00514.1 - 0.16 12.6 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Snf7 PF03357.21 CCV00515.1 - 8.4e-40 136.2 12.8 8.4e-40 136.2 12.8 1.5 1 1 1 2 2 2 1 Snf7 Ribosomal_60s PF00428.19 CCV00515.1 - 0.016 15.8 4.0 0.29 11.7 0.4 2.7 2 1 1 3 3 3 0 60s Acidic ribosomal protein FANCI_S1-cap PF14674.6 CCV00515.1 - 0.19 11.9 2.3 2.1 8.5 0.4 2.7 2 0 0 2 2 2 0 FANCI solenoid 1 cap SOAR PF16533.5 CCV00515.1 - 0.31 11.0 4.8 0.19 11.7 2.0 2.0 1 1 1 2 2 2 0 STIM1 Orai1-activating region TEX13 PF15186.6 CCV00515.1 - 4 7.1 9.2 0.79 9.4 5.2 1.8 2 1 0 2 2 2 0 Testis-expressed sequence 13 protein family MFS_1 PF07690.16 CCV00516.1 - 9.5e-64 215.5 90.5 4.7e-32 111.3 39.4 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Regnase_1_C PF18561.1 CCV00516.1 - 0.0052 16.5 4.5 1.2 8.9 0.1 3.6 4 0 0 4 4 4 2 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain TIM21 PF08294.11 CCV00516.1 - 0.091 12.6 0.2 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 TIM21 Baculo_11_kDa PF06143.11 CCV00516.1 - 0.11 12.1 0.7 9.1 5.9 0.0 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family DUF2793 PF10983.8 CCV00516.1 - 0.14 12.1 0.2 0.34 10.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) KCH PF16944.5 CCV00516.1 - 0.58 9.9 10.7 2 8.1 0.4 3.9 4 0 0 4 4 4 0 Fungal potassium channel Mito_carr PF00153.27 CCV00520.1 - 1.5e-62 207.5 3.3 2.8e-22 78.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.31 CCV00521.1 - 1.3e-15 57.2 0.1 2.3e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain MerR_1 PF13411.6 CCV00521.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein DUF1977 PF09320.11 CCV00522.1 - 7.3e-18 64.8 0.2 8.9e-18 64.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) SEA PF01390.20 CCV00522.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 SEA domain TFIIS_C PF01096.18 CCV00523.1 - 4e-16 58.6 0.5 4e-16 58.6 0.5 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CCV00523.1 - 9.8e-07 28.6 6.7 0.0091 15.9 0.1 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 CCV00523.1 - 3.9e-05 23.6 6.1 0.032 14.2 0.1 2.9 2 1 0 2 2 2 2 Double zinc ribbon Prok-RING_1 PF14446.6 CCV00523.1 - 0.00041 20.2 7.6 0.0077 16.1 0.5 3.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 TF_Zn_Ribbon PF08271.12 CCV00523.1 - 0.0081 15.6 12.3 0.22 11.1 2.3 3.4 2 2 0 2 2 2 2 TFIIB zinc-binding HypA PF01155.19 CCV00523.1 - 0.012 15.6 4.0 1.5 8.8 1.8 2.7 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 CCV00523.1 - 0.02 14.8 6.1 0.68 9.9 0.1 2.8 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-TFIIB PF13453.6 CCV00523.1 - 0.021 14.1 0.8 0.021 14.1 0.8 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger IBR PF01485.21 CCV00523.1 - 0.026 14.8 4.0 0.55 10.5 1.2 2.4 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain A2L_zn_ribbon PF08792.10 CCV00523.1 - 0.042 13.6 8.3 0.21 11.3 0.1 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain zf_C2H2_10 PF18414.1 CCV00523.1 - 0.042 13.4 1.3 1.1 8.8 0.9 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger Terminase_GpA PF05876.12 CCV00523.1 - 0.046 12.3 0.5 0.048 12.2 0.5 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF1451 PF07295.11 CCV00523.1 - 0.082 12.9 4.0 1.3 9.1 0.1 2.9 3 0 0 3 3 3 0 Zinc-ribbon containing domain zf-H2C2_2 PF13465.6 CCV00523.1 - 0.11 13.0 0.1 0.11 13.0 0.1 3.0 4 1 0 4 4 3 0 Zinc-finger double domain Nop10p PF04135.12 CCV00523.1 - 0.12 12.4 1.4 0.99 9.5 0.1 2.6 1 1 1 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Baculo_LEF5_C PF11792.8 CCV00523.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.4 4 0 0 4 4 2 0 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_4 PF13717.6 CCV00523.1 - 0.21 11.6 10.4 15 5.6 0.2 4.1 3 1 1 4 4 4 0 zinc-ribbon domain Ribosomal_S27e PF01667.17 CCV00523.1 - 0.22 11.3 8.4 1.7 8.4 0.0 3.8 3 1 1 4 4 4 0 Ribosomal protein S27 Zn-ribbon_8 PF09723.10 CCV00523.1 - 0.22 11.7 13.0 8.2 6.6 0.7 3.4 2 2 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 CCV00523.1 - 0.26 11.6 5.8 20 5.6 0.8 3.4 3 1 0 3 3 3 0 zinc-ribbon zf-ribbon_3 PF13248.6 CCV00523.1 - 0.3 10.6 18.8 4.3 6.9 1.0 4.1 3 1 0 3 3 3 0 zinc-ribbon domain DUF1610 PF07754.11 CCV00523.1 - 0.36 10.8 0.2 0.36 10.8 0.2 3.8 4 0 0 4 4 3 0 Domain of unknown function (DUF1610) DNA_RNApol_7kD PF03604.13 CCV00523.1 - 0.37 10.5 8.6 0.47 10.2 0.2 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.6 CCV00523.1 - 0.61 9.9 17.0 1.1 9.0 0.6 4.0 4 0 0 4 4 4 0 zinc-ribbon domain UPF0547 PF10571.9 CCV00523.1 - 0.78 9.9 15.6 0.65 10.1 0.5 3.9 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DUF3268 PF11672.8 CCV00523.1 - 0.84 10.0 3.3 1.5 9.1 0.4 2.3 2 1 1 3 3 3 0 zinc-finger-containing domain Nudix_N_2 PF14803.6 CCV00523.1 - 1.1 9.2 12.5 5.5 7.0 3.0 3.8 2 2 0 2 2 2 0 Nudix N-terminal zf-IS66 PF13005.7 CCV00523.1 - 1.2 9.6 7.4 20 5.7 0.2 3.8 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 CpXC PF14353.6 CCV00523.1 - 1.7 8.7 8.9 5.8 7.0 0.2 3.6 2 1 2 4 4 4 0 CpXC protein zf-ISL3 PF14690.6 CCV00523.1 - 1.8 9.3 6.7 21 5.9 0.1 3.8 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_ribbon_SprT PF17283.2 CCV00523.1 - 2.6 8.0 6.1 37 4.3 0.3 3.3 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DUF2752 PF10825.8 CCV00523.1 - 3.9 7.6 0.0 3.9 7.6 0.0 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF2752) Zn_Tnp_IS1595 PF12760.7 CCV00523.1 - 4.8 7.2 9.6 4.5 7.3 2.9 3.2 2 2 1 3 3 3 0 Transposase zinc-ribbon domain DUF678 PF05077.12 CCV00523.1 - 6.6 6.9 9.2 3.8 7.7 0.4 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF678) DUF3797 PF12677.7 CCV00523.1 - 7.1 6.6 7.0 50 3.9 5.6 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3797) Lar_restr_allev PF14354.6 CCV00523.1 - 9.2 6.7 11.6 23 5.5 0.3 3.0 2 2 0 2 2 2 0 Restriction alleviation protein Lar HAGH_C PF16123.5 CCV00524.1 - 6e-19 68.4 0.0 1.1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CCV00524.1 - 5.3e-06 26.6 2.9 2.7e-05 24.3 2.9 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CCV00524.1 - 0.011 15.2 0.2 0.023 14.2 0.2 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain adh_short_C2 PF13561.6 CCV00525.1 - 8.2e-57 192.4 0.2 1.1e-56 192.0 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CCV00525.1 - 3.9e-48 163.5 1.3 5.7e-48 163.0 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CCV00525.1 - 2.8e-12 46.9 0.8 4.2e-12 46.3 0.8 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 CCV00525.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCV00525.1 - 0.0019 18.7 0.1 0.0042 17.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3Beta_HSD PF01073.19 CCV00525.1 - 0.013 14.5 0.3 0.019 14.0 0.3 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 CCV00525.1 - 0.05 13.8 0.6 0.16 12.2 0.2 2.0 1 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Vmethyltransf PF01660.17 CCV00525.1 - 0.052 12.4 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Viral methyltransferase Epimerase PF01370.21 CCV00525.1 - 0.083 12.3 0.0 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 CCV00525.1 - 0.12 12.9 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_25 PF13649.6 CCV00525.1 - 0.17 12.6 0.3 0.62 10.8 0.2 2.0 2 1 0 2 2 2 0 Methyltransferase domain WD40 PF00400.32 CCV00526.1 - 3.6e-30 103.6 22.0 1.2e-07 32.3 0.1 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat Hira PF07569.11 CCV00526.1 - 4.3e-19 69.1 0.1 1.8e-18 67.1 0.1 1.9 1 1 0 1 1 1 1 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 CCV00526.1 - 3.5e-12 46.4 0.2 0.27 11.6 0.0 7.0 5 1 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 CCV00526.1 - 1.1e-05 24.9 0.5 0.0002 20.8 0.1 2.2 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region Ge1_WD40 PF16529.5 CCV00526.1 - 0.028 13.4 0.2 3.4 6.6 0.0 3.2 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein T2SSM_b PF10741.9 CCV00526.1 - 0.11 12.3 0.5 0.25 11.2 0.5 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b HIRA_B PF09453.10 CCV00526.1 - 0.41 10.5 2.6 1.1 9.2 2.6 1.8 1 0 0 1 1 1 0 HIRA B motif PD40 PF07676.12 CCV00526.1 - 1.3 9.0 5.6 48 4.1 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat RabGAP-TBC PF00566.18 CCV00529.1 - 5e-38 130.9 0.0 8.2e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Elongin_A PF06881.11 CCV00529.1 - 2.3e-29 102.0 0.3 4.4e-29 101.1 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Cyclin PF08613.11 CCV00530.1 - 1.3e-08 35.4 0.0 2.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin DciA PF05258.12 CCV00530.1 - 0.052 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA AAA_lid_8 PF17868.1 CCV00530.1 - 0.087 12.7 0.1 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA lid domain CorA PF01544.18 CCV00531.1 - 7.7e-11 41.8 4.2 1.1e-10 41.3 4.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4806 PF16064.5 CCV00531.1 - 0.48 10.8 1.6 1.3 9.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) YiaAB PF05360.14 CCV00531.1 - 1.5 9.1 4.5 3.1 8.1 4.2 1.7 1 1 1 2 2 2 0 yiaA/B two helix domain FlaC_arch PF05377.11 CCV00531.1 - 3.3 8.2 6.7 2.3 8.7 2.4 2.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TAL_FSA PF00923.19 CCV00532.1 - 1.4e-93 313.4 0.0 1.6e-93 313.2 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase GNAT_acetyltr_2 PF13718.6 CCV00533.1 - 3.6e-87 291.5 0.0 6.6e-87 290.6 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 CCV00533.1 - 2e-64 216.7 0.0 9.1e-64 214.5 0.0 2.0 2 0 0 2 2 2 1 Helicase tRNA_bind_2 PF13725.6 CCV00533.1 - 9.1e-53 179.4 0.0 1.5e-52 178.7 0.0 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.11 CCV00533.1 - 7.6e-31 105.9 0.0 2.7e-30 104.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 CCV00533.1 - 0.0034 17.1 2.0 0.014 15.1 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CCV00533.1 - 0.0084 16.4 0.0 0.1 12.9 0.0 2.7 1 1 1 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 CCV00533.1 - 0.036 14.3 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCV00533.1 - 0.16 12.4 0.0 0.47 10.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Methyltransf_25 PF13649.6 CCV00534.1 - 0.11 13.2 0.0 1.5 9.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Bromodomain PF00439.25 CCV00535.1 - 3e-17 62.5 0.1 5.1e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 Bromodomain Myb_DNA-bind_6 PF13921.6 CCV00535.1 - 0.12 12.6 0.0 0.92 9.8 0.0 2.3 1 1 0 1 1 1 0 Myb-like DNA-binding domain SPX PF03105.19 CCV00535.1 - 7 6.5 11.4 9.5 6.0 11.4 1.2 1 0 0 1 1 1 0 SPX domain Complex1_49kDa PF00346.19 CCV00536.1 - 1.5e-117 391.5 0.0 2.1e-117 391.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 CCV00536.1 - 0.035 13.0 0.0 0.067 12.1 0.0 1.5 1 0 0 1 1 1 0 Nickel-dependent hydrogenase COPIIcoated_ERV PF07970.12 CCV00537.1 - 1.7e-77 260.2 0.3 2.7e-77 259.6 0.3 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CCV00537.1 - 1.7e-25 89.1 0.0 3.2e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Uds1 PF15456.6 CCV00538.1 - 1e-13 51.6 11.0 1e-13 51.6 11.0 6.2 5 2 1 6 6 6 1 Up-regulated During Septation CAP_GLY PF01302.25 CCV00539.1 - 4.4e-23 81.1 0.4 7.8e-23 80.3 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 CCV00539.1 - 4.4e-08 33.5 0.0 6.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain DSPc PF00782.20 CCV00540.1 - 1.3e-25 89.8 0.0 1.7e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF442 PF04273.13 CCV00540.1 - 0.00015 21.8 0.1 0.00047 20.2 0.1 1.8 2 0 0 2 2 2 1 Putative phosphatase (DUF442) Y_phosphatase3 PF13350.6 CCV00540.1 - 0.061 13.3 0.2 0.14 12.1 0.2 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 CCV00540.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CUE PF02845.16 CCV00541.1 - 4.2e-09 35.9 0.0 6.2e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain HTH_ParB PF17762.1 CCV00541.1 - 0.17 11.7 0.2 0.3 10.9 0.2 1.3 1 0 0 1 1 1 0 HTH domain found in ParB protein zf-H2C2_2 PF13465.6 CCV00542.1 - 6.6e-08 32.6 7.3 2.3e-07 30.9 3.8 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 CCV00542.1 - 3.8e-07 30.2 16.6 0.00022 21.5 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCV00542.1 - 0.00098 19.8 18.9 0.0042 17.8 1.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CCV00542.1 - 0.018 15.3 0.8 0.088 13.1 0.9 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 CCV00542.1 - 0.025 15.0 5.9 0.24 11.9 1.6 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 CCV00542.1 - 1.9 8.9 6.8 16 6.0 2.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCV00542.1 - 5.9 7.0 12.9 0.091 12.8 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger UCH PF00443.29 CCV00543.1 - 1e-43 149.7 0.0 1.2e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCV00543.1 - 2.4e-15 56.9 0.1 1.4e-09 38.0 0.1 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CCV00543.1 - 5.2e-10 38.9 0.0 9.4e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DALR_1 PF05746.15 CCV00543.1 - 0.071 13.3 0.1 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 DALR anticodon binding domain Noc2 PF03715.13 CCV00544.1 - 9.3e-111 369.8 0.0 1.4e-110 369.3 0.0 1.2 1 0 0 1 1 1 1 Noc2p family XPC-binding PF09280.11 CCV00544.1 - 0.34 10.7 4.4 0.97 9.2 0.0 3.5 4 0 0 4 4 4 0 XPC-binding domain BUD22 PF09073.10 CCV00544.1 - 4.3 6.6 20.0 6.2 6.1 20.0 1.2 1 0 0 1 1 1 0 BUD22 WD40 PF00400.32 CCV00545.1 - 2e-10 41.1 0.2 0.022 15.6 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCV00545.1 - 0.0029 17.9 0.0 3.5 8.0 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 CCV00545.1 - 0.069 13.1 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat GvpL_GvpF PF06386.11 CCV00545.1 - 0.39 10.6 4.6 0.66 9.9 4.6 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF UIM PF02809.20 CCV00545.1 - 4.1 7.6 6.8 0.32 11.0 1.3 2.2 2 0 0 2 2 2 0 Ubiquitin interaction motif SH3_9 PF14604.6 CCV00546.1 - 6.7e-31 105.9 3.5 1.5e-15 56.7 0.2 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CCV00546.1 - 1.7e-26 91.6 2.4 1.7e-12 46.7 0.1 2.1 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CCV00546.1 - 6.7e-16 57.7 0.0 7.7e-08 31.9 0.0 2.1 2 0 0 2 2 2 2 Variant SH3 domain Glyoxalase_3 PF13468.6 CCV00546.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain CAF1A PF12253.8 CCV00546.1 - 4.9 7.4 7.0 3.3 8.0 0.9 2.3 2 1 0 2 2 2 0 Chromatin assembly factor 1 subunit A Cofilin_ADF PF00241.20 CCV00547.1 - 2.4e-20 72.5 0.0 3.4e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein EMC1_C PF07774.13 CCV00548.1 - 3e-54 184.0 0.0 4.5e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CCV00548.1 - 0.00071 19.2 3.2 0.16 11.6 0.1 3.5 4 0 0 4 4 4 2 PQQ-like domain DUF1752 PF08550.10 CCV00549.1 - 4.7e-12 45.5 4.8 8.7e-12 44.7 4.8 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RNA_pol_A_bac PF01000.26 CCV00550.1 - 1.3e-29 102.8 0.0 2.7e-29 101.8 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CCV00550.1 - 3.3e-09 36.0 0.0 4.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF883 PF05957.13 CCV00551.1 - 0.00039 21.0 12.3 0.097 13.3 1.8 3.7 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) DUF745 PF05335.13 CCV00551.1 - 0.0012 18.6 21.3 0.0016 18.2 21.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) Apo-CIII PF05778.12 CCV00551.1 - 0.002 17.7 12.5 1.3 8.7 0.1 4.2 1 1 2 3 3 3 2 Apolipoprotein CIII (Apo-CIII) Chlorosome_CsmC PF11098.8 CCV00551.1 - 0.0033 17.4 6.7 0.28 11.2 1.0 2.2 2 0 0 2 2 2 2 Chlorosome envelope protein C Apolipoprotein PF01442.18 CCV00551.1 - 0.0041 17.0 9.5 0.044 13.7 9.0 2.2 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain RRF PF01765.19 CCV00551.1 - 0.026 14.5 3.7 2.4 8.1 0.5 2.2 1 1 1 2 2 2 0 Ribosome recycling factor ApoO PF09769.9 CCV00551.1 - 0.095 12.7 5.1 30 4.6 0.1 3.7 1 1 3 4 4 4 0 Apolipoprotein O Phasin_2 PF09361.10 CCV00551.1 - 0.12 12.7 16.8 0.066 13.5 8.0 3.0 1 1 2 3 3 3 0 Phasin protein PhaP_Bmeg PF09602.10 CCV00551.1 - 0.4 10.6 6.5 0.5 10.3 2.2 2.3 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF842 PF05811.13 CCV00551.1 - 0.51 10.0 5.0 15 5.3 5.0 2.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) YtxH PF12732.7 CCV00551.1 - 0.65 10.6 16.2 1.8e+04 -3.9 16.2 3.7 1 1 0 1 1 0 0 YtxH-like protein Prominin PF05478.11 CCV00551.1 - 0.81 7.6 2.7 0.93 7.4 2.7 1.1 1 0 0 1 1 1 0 Prominin BMFP PF04380.13 CCV00551.1 - 0.95 10.0 4.7 1.8 9.1 0.3 3.2 1 1 3 4 4 4 0 Membrane fusogenic activity Vps53_N PF04100.12 CCV00551.1 - 1 8.2 6.3 2.3 7.1 2.1 2.3 1 1 2 3 3 3 0 Vps53-like, N-terminal ATP-synt_B PF00430.18 CCV00551.1 - 1.2 9.2 18.2 0.38 10.8 6.7 2.7 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) SNARE PF05739.19 CCV00551.1 - 1.2 9.1 9.4 25 5.0 0.2 4.3 3 1 2 5 5 5 0 SNARE domain Alanine_zipper PF11839.8 CCV00551.1 - 3.6 8.0 27.4 7 7.1 6.3 3.4 2 1 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein dbPDZ_assoc PF16610.5 CCV00551.1 - 3.6 7.9 7.1 6.6 7.0 1.2 2.4 1 1 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 V-ATPase_G_2 PF16999.5 CCV00551.1 - 6.7 7.2 13.1 4.1 7.9 6.6 2.9 1 1 1 3 3 3 0 Vacuolar (H+)-ATPase G subunit DivIVA PF05103.13 CCV00551.1 - 7.3 6.7 11.9 1 9.4 4.0 2.5 1 1 1 2 2 2 0 DivIVA protein PMEI PF04043.15 CCV00551.1 - 8.5 6.7 12.9 6.4 7.1 1.0 2.0 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor DUF2470 PF10615.9 CCV00553.1 - 3.1e-20 72.6 0.4 4.1e-20 72.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) RSN1_7TM PF02714.15 CCV00554.1 - 1.1e-66 225.0 21.0 1.1e-66 225.0 21.0 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CCV00554.1 - 4.3e-34 117.5 3.9 4.3e-34 117.5 3.9 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CCV00554.1 - 2.2e-33 115.9 0.2 4.9e-33 114.8 0.1 1.7 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 CCV00554.1 - 1.3e-09 38.1 0.5 3.1e-09 36.9 0.5 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Insulin_TMD PF17870.1 CCV00554.1 - 0.055 13.5 3.1 0.58 10.3 0.1 3.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF21 PF01595.20 CCV00555.1 - 8e-38 129.9 0.4 1.2e-37 129.3 0.4 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CCV00555.1 - 0.00021 21.7 1.0 0.066 13.7 0.0 3.3 3 0 0 3 3 3 2 CBS domain MMR_HSR1_Xtn PF16897.5 CCV00556.1 - 4.6e-42 142.3 1.0 3.8e-41 139.4 0.7 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CCV00556.1 - 4e-21 74.8 0.0 7.2e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CCV00556.1 - 1.7e-20 73.2 0.0 3.5e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCV00556.1 - 5.6e-09 35.7 0.3 1.5e-08 34.3 0.1 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CCV00556.1 - 0.072 12.1 0.7 0.15 11.0 0.7 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CCV00556.1 - 0.083 12.9 0.3 2.6 8.1 0.0 2.2 1 1 1 2 2 2 0 Dynamin family DUF211 PF02680.14 CCV00556.1 - 0.11 12.7 0.3 0.38 10.9 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 zn-ribbon_14 PF16503.5 CCV00557.1 - 2e-17 62.4 2.4 2e-17 62.4 2.4 3.4 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 CCV00557.1 - 1.8e-12 47.4 0.0 3.8e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 CCV00557.1 - 0.14 10.9 0.2 0.79 8.5 0.2 2.0 1 1 0 1 1 1 0 tRNA methyl transferase TF_Zn_Ribbon PF08271.12 CCV00557.1 - 2 8.0 12.9 0.067 12.7 1.0 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding TPR_2 PF07719.17 CCV00558.1 - 0.008 16.2 14.7 0.11 12.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCV00558.1 - 0.065 13.3 4.4 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCV00558.1 - 0.25 11.2 1.6 4.1 7.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCV00558.1 - 0.51 10.7 0.1 0.51 10.7 0.1 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCV00558.1 - 0.85 10.4 0.1 0.85 10.4 0.1 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Cation_efflux PF01545.21 CCV00559.1 - 1.6e-21 77.0 8.5 4.3e-21 75.6 8.5 1.7 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CCV00559.1 - 0.00019 21.5 0.0 0.00045 20.3 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Iso_dh PF00180.20 CCV00560.1 - 2.6e-116 388.6 0.0 3e-116 388.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Acatn PF13000.7 CCV00561.1 - 2.7e-150 501.5 14.9 3.6e-71 240.3 8.5 3.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 CCV00561.1 - 0.069 12.0 11.9 0.097 11.5 11.0 1.6 1 1 0 1 1 1 0 MFS_1 like family 4HBT PF03061.22 CCV00562.1 - 4.5e-08 33.3 0.0 8.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily FGAR-AT_N PF18076.1 CCV00562.1 - 0.18 11.8 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal MFS_1 PF07690.16 CCV00563.1 - 2.4e-57 194.5 40.9 1.3e-29 103.3 14.8 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily STAT1_TAZ2bind PF12162.8 CCV00563.1 - 0.016 14.7 1.8 3.7 7.2 0.1 2.5 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain Tom5 PF10642.9 CCV00563.1 - 0.017 15.1 0.0 6.8 6.8 0.0 3.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase DUF4293 PF14126.6 CCV00563.1 - 0.024 14.9 7.5 2.2 8.5 0.1 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) DUF3481 PF11980.8 CCV00563.1 - 0.059 13.1 0.1 5.1 6.9 0.0 2.8 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein NDUF_B12 PF08122.12 CCV00563.1 - 0.16 12.0 0.6 18 5.5 0.2 3.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family UCH PF00443.29 CCV00564.1 - 3.2e-33 115.3 0.0 4.1e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CCV00564.1 - 1.3e-11 44.7 0.9 2.3e-11 43.8 0.9 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_M18 PF02127.15 CCV00565.1 - 4.1e-147 490.4 0.0 5.1e-147 490.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CCV00565.1 - 0.018 14.1 0.0 0.28 10.2 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase GIDA PF01134.22 CCV00567.1 - 6.8e-125 417.2 0.0 1.7e-124 415.9 0.0 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 CCV00567.1 - 1.1e-53 182.6 0.0 1.5e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 CCV00567.1 - 2.1e-06 27.4 2.1 6.7e-06 25.7 2.7 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CCV00567.1 - 0.00011 21.6 2.6 0.0018 17.6 2.7 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CCV00567.1 - 0.0061 15.7 5.6 0.0062 15.7 3.7 2.0 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 CCV00567.1 - 0.0081 15.5 3.0 0.014 14.7 3.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 CCV00567.1 - 0.009 16.2 2.2 0.45 10.8 1.5 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CCV00567.1 - 0.016 14.8 3.1 0.67 9.5 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CCV00567.1 - 0.025 13.3 1.2 0.048 12.4 1.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 CCV00567.1 - 0.025 13.8 0.2 0.051 12.8 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCV00567.1 - 0.031 14.8 0.3 0.087 13.4 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CCV00567.1 - 0.14 12.1 1.0 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Peptidase_M28 PF04389.17 CCV00568.1 - 4.1e-35 121.3 0.0 6.2e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CCV00568.1 - 0.0048 16.6 0.0 0.0095 15.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Phage_holin_2_4 PF16082.5 CCV00568.1 - 0.25 11.1 1.6 0.98 9.2 1.2 2.3 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like Hamartin PF04388.12 CCV00569.1 - 0.034 12.8 5.3 0.052 12.2 5.3 1.2 1 0 0 1 1 1 0 Hamartin protein COPI_C PF06957.11 CCV00569.1 - 1 8.0 6.7 1.8 7.3 6.7 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus PrmA PF06325.13 CCV00570.1 - 3.4e-12 46.4 0.0 5.3e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CCV00570.1 - 6.8e-11 42.7 0.1 2.9e-10 40.7 0.0 2.2 2 1 1 3 3 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCV00570.1 - 2.2e-10 40.5 0.0 4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCV00570.1 - 2.7e-08 34.3 0.0 1.3e-07 32.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCV00570.1 - 7e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 CCV00570.1 - 2e-05 25.6 0.2 0.00084 20.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCV00570.1 - 3.3e-05 24.5 0.0 0.00011 22.8 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCV00570.1 - 3.3e-05 23.8 0.0 6.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CCV00570.1 - 3.4e-05 23.3 0.0 6.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 CCV00570.1 - 0.00043 20.2 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CCV00570.1 - 0.0027 17.4 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 CCV00570.1 - 0.0029 17.4 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 CCV00570.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 CCV00570.1 - 0.01 14.8 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PRMT5 PF05185.16 CCV00570.1 - 0.025 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 CCV00570.1 - 0.045 13.7 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 CCV00570.1 - 0.08 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB eIF2A PF08662.11 CCV00571.1 - 2.5e-81 272.2 0.0 6.5e-77 257.8 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CCV00571.1 - 5.8e-06 27.0 0.1 2.1 9.4 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCV00571.1 - 4.7e-05 23.6 0.0 0.088 13.1 0.0 4.0 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CDV3 PF15359.6 CCV00571.1 - 1.4 9.4 4.3 5.5 7.5 4.3 2.0 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 Glyco_hydro_31 PF01055.26 CCV00572.1 - 7.4e-127 424.2 0.9 9.6e-127 423.8 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CCV00572.1 - 2.3e-18 66.3 0.1 2.4e-17 63.0 0.0 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 CCV00572.1 - 0.0019 18.4 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) T2SSJ PF11612.8 CCV00572.1 - 0.04 14.1 0.1 0.086 13.0 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J ABC_tran PF00005.27 CCV00573.1 - 7.1e-21 75.2 0.0 2.4e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CCV00573.1 - 7.7e-05 22.6 8.3 0.0024 17.7 0.6 3.2 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CCV00573.1 - 0.0034 17.8 1.2 0.046 14.1 0.5 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCV00573.1 - 0.0038 17.5 0.0 0.54 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CCV00573.1 - 0.007 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 CCV00573.1 - 0.011 15.9 0.0 0.043 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CCV00573.1 - 0.024 14.4 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 CCV00573.1 - 0.026 14.8 0.0 0.57 10.4 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 CCV00573.1 - 0.034 14.0 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 CCV00573.1 - 0.041 14.4 0.0 0.067 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 CCV00573.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Roc PF08477.13 CCV00573.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CCV00573.1 - 0.27 10.9 0.0 0.45 10.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pantoate_transf PF02548.15 CCV00574.1 - 7.8e-80 268.0 3.4 1.5e-77 260.5 3.4 2.1 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Peptidase_C2 PF00648.21 CCV00575.1 - 9.6e-18 64.2 0.0 2.4e-17 62.9 0.0 1.6 1 1 1 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 CCV00575.1 - 0.002 18.4 0.0 0.077 13.3 0.0 2.8 2 1 0 2 2 2 1 Calpain large subunit, domain III MIT PF04212.18 CCV00575.1 - 0.027 14.5 0.6 0.085 12.9 0.6 1.7 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain RNase_T PF00929.24 CCV00576.1 - 1.3e-19 71.3 0.0 3.7e-19 69.9 0.0 1.6 1 1 0 1 1 1 1 Exonuclease Lectin_leg-like PF03388.13 CCV00577.1 - 2.7e-58 197.0 0.1 4.5e-58 196.3 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CCV00577.1 - 2e-13 50.8 0.2 3.1e-13 50.2 0.2 1.3 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 CCV00577.1 - 5.4e-05 22.9 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain Y_phosphatase PF00102.27 CCV00578.1 - 2.4e-57 194.2 0.5 4.7e-57 193.3 0.5 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 CCV00578.1 - 1.2e-09 38.7 0.0 7.6e-06 26.4 0.0 3.1 2 1 0 2 2 2 2 Rhodanese-like domain DSPc PF00782.20 CCV00578.1 - 0.0017 18.2 0.0 0.004 17.0 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CCV00578.1 - 0.0085 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family YabA PF06156.13 CCV00579.1 - 0.032 14.9 1.3 0.032 14.9 1.3 5.4 2 1 2 4 4 4 0 Initiation control protein YabA DUF2464 PF10240.9 CCV00579.1 - 2.2 7.8 9.1 0.31 10.6 0.6 2.6 2 1 1 3 3 3 0 Multivesicular body subunit 12 WD40 PF00400.32 CCV00580.1 - 1e-06 29.3 19.4 0.00097 19.9 0.3 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.22 CCV00580.1 - 0.00018 21.7 0.0 0.00033 20.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.26 CCV00580.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme BBS2_C PF14782.6 CCV00580.1 - 0.26 10.0 0.0 0.4 9.4 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal SLD3 PF08639.10 CCV00581.1 - 1.9e-09 36.9 0.0 8.1e-09 34.8 0.0 1.7 1 1 1 2 2 2 2 DNA replication regulator SLD3 Uso1_p115_head PF04869.14 CCV00582.1 - 3.4e-61 207.1 0.0 3.1e-60 203.9 0.0 2.6 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 CCV00582.1 - 3.3e-09 37.2 21.6 3.3e-09 37.2 21.6 2.9 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Arm_vescicular PF18770.1 CCV00582.1 - 0.00018 21.4 0.1 0.00059 19.7 0.1 1.9 1 0 0 1 1 1 1 Armadillo tether-repeat of vescicular transport factor MMS19_N PF14500.6 CCV00582.1 - 0.0054 16.3 0.2 0.11 12.1 0.1 2.9 1 1 1 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF4042 PF13251.6 CCV00582.1 - 0.0068 16.1 1.0 1.2 8.8 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4042) Arm PF00514.23 CCV00582.1 - 0.07 13.2 2.0 1.6 8.9 0.1 4.0 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat CASP_C PF08172.12 CCV00582.1 - 8.9 5.6 19.4 0.65 9.3 7.8 2.3 2 0 0 2 2 2 0 CASP C terminal FMN_dh PF01070.18 CCV00583.1 - 1.4e-109 366.4 0.0 1.7e-109 366.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CCV00583.1 - 8.9e-21 73.8 0.0 1.7e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CCV00583.1 - 2.5e-06 26.9 0.0 4.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CCV00583.1 - 0.0016 17.5 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain G-alpha PF00503.20 CCV00584.1 - 3.1e-53 181.2 0.1 3.6e-53 181.0 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CCV00584.1 - 1.5e-06 27.8 0.1 3.9e-06 26.4 0.1 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family SMP_C2CD2L PF18696.1 CCV00584.1 - 0.086 12.7 0.1 0.18 11.6 0.0 1.5 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain Gcn1_N PF12074.8 CCV00585.1 - 7.4e-25 88.0 26.7 1.1e-23 84.1 5.6 5.7 7 0 0 7 7 7 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 CCV00585.1 - 2.3e-23 80.3 57.5 0.017 15.3 0.4 23.6 24 0 0 24 24 23 4 HEAT repeat HEAT_2 PF13646.6 CCV00585.1 - 1.4e-13 51.0 131.8 0.00012 22.4 0.2 18.7 10 5 11 22 22 21 12 HEAT repeats HEAT_EZ PF13513.6 CCV00585.1 - 2.5e-12 47.0 117.4 3.5e-05 24.2 0.4 22.8 19 6 6 25 25 22 9 HEAT-like repeat Cnd1 PF12717.7 CCV00585.1 - 2.8e-12 47.0 0.4 1.5 8.9 0.0 8.0 5 2 3 8 8 8 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CCV00585.1 - 2.1e-07 31.5 0.0 3.4 8.3 0.0 7.2 7 1 1 8 8 7 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CCV00585.1 - 1.9e-05 24.3 0.7 3.2 7.2 0.0 6.3 6 2 2 8 8 8 2 CLASP N terminal IFRD PF05004.13 CCV00585.1 - 3.7e-05 23.0 4.0 7.2 5.6 0.0 6.4 6 2 1 8 8 8 2 Interferon-related developmental regulator (IFRD) RIX1 PF08167.12 CCV00585.1 - 0.00085 19.1 4.8 0.19 11.4 0.0 5.9 7 0 0 7 7 6 1 rRNA processing/ribosome biogenesis DUF3437 PF11919.8 CCV00585.1 - 0.0054 16.6 1.3 1.5 8.8 0.0 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) Adaptin_N PF01602.20 CCV00585.1 - 0.015 13.9 6.2 3.1 6.3 0.0 5.9 5 2 1 6 6 6 0 Adaptin N terminal region UME PF08064.13 CCV00585.1 - 0.024 14.6 0.0 15 5.6 0.0 5.4 5 2 1 6 6 5 0 UME (NUC010) domain AMP-binding_C PF13193.6 CCV00585.1 - 0.069 14.1 3.7 0.28 12.2 0.3 4.1 3 0 0 3 3 2 0 AMP-binding enzyme C-terminal domain Phage_TAC_9 PF10876.8 CCV00585.1 - 0.099 12.7 1.5 17 5.5 0.0 3.8 3 1 1 4 4 3 0 Phage tail assemb.y chaperone protein, TAC Arm PF00514.23 CCV00585.1 - 1.4 9.1 25.2 1.8 8.7 0.1 9.6 10 0 0 10 10 8 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 CCV00585.1 - 1.8 8.7 8.4 9.2 6.5 0.0 6.0 7 0 0 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4042 PF13251.6 CCV00585.1 - 3.5 7.3 8.6 18 5.0 0.1 6.0 7 1 0 7 7 7 0 Domain of unknown function (DUF4042) Cyclin_N PF00134.23 CCV00586.1 - 1.6e-08 34.4 0.1 2.5e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCV00586.1 - 1.7e-05 25.2 0.2 4.5e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 Cyclin ABC_tran PF00005.27 CCV00587.1 - 7.6e-60 201.4 0.0 1.1e-28 100.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CCV00587.1 - 3.6e-56 190.8 0.0 9.3e-29 100.9 0.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CCV00587.1 - 3.1e-10 39.9 0.0 0.017 14.6 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CCV00587.1 - 1.3e-09 38.6 9.6 0.00048 20.5 0.1 4.1 3 2 1 4 4 3 2 AAA ATPase domain AAA_21 PF13304.6 CCV00587.1 - 1.8e-08 34.6 0.0 0.1 12.4 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCV00587.1 - 2.6e-08 33.5 0.2 0.0068 16.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 CCV00587.1 - 1.2e-06 28.8 0.1 0.094 12.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CCV00587.1 - 2.3e-06 27.9 0.1 0.34 11.2 0.0 3.7 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 CCV00587.1 - 3e-05 23.0 2.1 0.001 18.0 0.0 3.1 4 0 0 4 4 3 1 Predicted ATPase of the ABC class APS_kinase PF01583.20 CCV00587.1 - 3.5e-05 23.8 0.1 0.0078 16.1 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 CCV00587.1 - 4.4e-05 22.8 0.0 0.07 12.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.6 CCV00587.1 - 4.7e-05 23.1 11.8 0.0059 16.2 3.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.6 CCV00587.1 - 8.2e-05 22.9 0.0 0.21 11.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CCV00587.1 - 0.0002 21.3 0.1 1.1 9.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 CCV00587.1 - 0.00022 21.2 0.1 0.67 9.8 0.1 2.8 3 0 0 3 3 2 2 NACHT domain SbcCD_C PF13558.6 CCV00587.1 - 0.00025 21.2 2.7 2.2 8.6 0.0 4.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 CCV00587.1 - 0.00041 20.9 0.0 0.42 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCV00587.1 - 0.00089 19.2 0.1 0.98 9.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 CCV00587.1 - 0.0014 18.8 1.1 0.34 11.0 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain SRP54 PF00448.22 CCV00587.1 - 0.0022 17.7 0.1 0.27 10.8 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Ploopntkinase3 PF18751.1 CCV00587.1 - 0.0033 17.4 0.1 3.2 7.6 0.0 2.8 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 G-alpha PF00503.20 CCV00587.1 - 0.0059 15.8 0.0 0.95 8.6 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit AAA_24 PF13479.6 CCV00587.1 - 0.0075 16.0 0.1 1.3 8.7 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 CCV00587.1 - 0.0082 16.6 0.0 4.4 7.8 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CCV00587.1 - 0.0093 16.0 2.2 1.5 8.8 0.0 3.2 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 CCV00587.1 - 0.021 15.2 0.3 7.2 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CCV00587.1 - 0.028 14.1 10.7 0.23 11.2 0.1 3.7 3 1 0 3 3 2 0 AAA domain MobB PF03205.14 CCV00587.1 - 0.03 14.2 0.0 0.82 9.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 CCV00587.1 - 0.038 13.8 0.1 5 6.8 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 CCV00587.1 - 0.044 13.4 0.2 0.87 9.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 CCV00587.1 - 0.055 14.0 0.2 9.6 6.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CCV00587.1 - 0.057 12.8 0.1 7.7 5.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CCV00587.1 - 0.079 13.0 0.4 7.4 6.7 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 CCV00587.1 - 0.092 12.4 0.0 7.1 6.2 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 CCV00587.1 - 0.095 11.9 0.4 7.8 5.6 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 CCV00587.1 - 0.096 12.7 0.0 13 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCV00587.1 - 0.1 13.0 0.1 12 6.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 CCV00587.1 - 0.15 11.7 0.0 2.4 7.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 CCV00587.1 - 0.25 11.3 0.0 5.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit HSP70 PF00012.20 CCV00588.1 - 1.1e-230 766.9 3.7 1.4e-230 766.5 3.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCV00588.1 - 9.8e-17 60.8 0.2 1.6e-16 60.1 0.2 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.18 CCV00588.1 - 0.012 14.9 0.3 0.086 12.1 0.1 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DDR PF08841.10 CCV00588.1 - 0.016 14.2 0.2 0.14 11.1 0.1 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain StbA PF06406.11 CCV00588.1 - 0.044 13.0 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 StbA protein FGGY_C PF02782.16 CCV00588.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Zincin_2 PF10103.9 CCV00588.1 - 0.093 12.0 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase Ribosomal_S2 PF00318.20 CCV00589.1 - 1.6e-52 177.8 0.0 3e-52 177.0 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S2 RNA_pol_L PF01193.24 CCV00589.1 - 0.14 11.6 0.0 0.85 9.1 0.0 2.1 2 1 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain SNF5 PF04855.12 CCV00590.1 - 6.4e-59 199.6 0.0 9.2e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 CCV00590.1 - 3.1e-05 23.5 1.0 6.4e-05 22.5 1.0 1.6 1 0 0 1 1 1 1 GATA zinc finger PITH PF06201.13 CCV00591.1 - 4.6e-30 104.8 0.0 5.6e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain UPF0016 PF01169.19 CCV00593.1 - 2.6e-40 136.6 18.8 4.6e-21 74.9 2.5 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.19 CCV00593.1 - 0.0026 17.4 13.5 0.016 14.9 13.7 1.9 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE TerC PF03741.16 CCV00593.1 - 0.0086 15.8 5.6 0.4 10.3 0.0 2.2 2 0 0 2 2 2 2 Integral membrane protein TerC family Trp_oprn_chp PF09534.10 CCV00593.1 - 0.058 13.2 10.7 0.38 10.5 7.5 2.3 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FAM70 PF14967.6 CCV00593.1 - 0.41 10.1 1.4 12 5.3 0.2 2.1 2 0 0 2 2 2 0 FAM70 protein LysE PF01810.18 CCV00593.1 - 0.99 8.8 14.5 0.95 8.9 3.4 2.2 2 0 0 2 2 2 0 LysE type translocator DUF4231 PF14015.6 CCV00593.1 - 1.6 9.3 7.3 1.5 9.3 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) 5TM-5TMR_LYT PF07694.12 CCV00593.1 - 1.9 8.0 12.1 1 8.8 4.8 2.6 2 1 1 3 3 3 0 5TMR of 5TMR-LYT DUF543 PF04418.12 CCV00593.1 - 5.2 7.1 7.4 1.3 9.1 1.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF543) Sad1_UNC PF07738.13 CCV00594.1 - 4e-25 88.4 0.0 6.7e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RhoGEF PF00621.20 CCV00595.1 - 5.7e-28 98.4 0.0 1.2e-27 97.3 0.0 1.6 1 1 0 1 1 1 1 RhoGEF domain Cellulase PF00150.18 CCV00595.1 - 2.5e-14 53.4 2.1 4.8e-14 52.5 2.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Phage_lysis PF03245.13 CCV00595.1 - 0.056 13.6 0.3 0.17 12.0 0.3 1.9 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Hexapep PF00132.24 CCV00596.1 - 1.1e-12 47.1 9.9 0.00026 20.6 3.8 5.1 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CCV00596.1 - 0.0002 21.0 8.5 0.0013 18.4 0.7 3.2 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CCV00596.1 - 0.002 17.2 0.0 0.0028 16.7 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase NAPRTase PF04095.16 CCV00597.1 - 6.4e-38 130.7 0.0 1.1e-37 129.9 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CCV00597.1 - 2.6e-28 98.9 0.0 1.6e-27 96.3 0.0 2.0 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain EF-hand_6 PF13405.6 CCV00598.1 - 5.6e-06 25.9 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CCV00598.1 - 6.9e-06 26.4 0.1 0.15 12.5 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CCV00598.1 - 0.0041 16.6 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CCV00598.1 - 0.038 13.9 0.1 4.6 7.2 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 CCV00598.1 - 0.045 13.3 0.3 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 EF hand UPF0220 PF05255.11 CCV00599.1 - 8.5e-54 181.5 1.2 9.6e-54 181.4 1.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Myb_Cef PF11831.8 CCV00600.1 - 5.8e-20 71.9 0.1 5.8e-20 71.9 0.1 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 CCV00600.1 - 1.1e-14 54.4 5.5 1.9e-08 34.4 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCV00600.1 - 1.1e-14 54.4 6.8 2.4e-08 34.1 3.6 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Aminotran_1_2 PF00155.21 CCV00601.1 - 4.6e-54 184.0 0.0 5.9e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CCV00601.1 - 0.14 11.1 0.0 0.44 9.4 0.0 1.7 1 1 1 2 2 2 0 Aminotransferase class-V Med17 PF10156.9 CCV00602.1 - 6.1e-13 48.3 0.0 9.9e-13 47.6 0.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex FKBP_C PF00254.28 CCV00603.1 - 3e-33 114.0 0.0 3.7e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase LSM PF01423.22 CCV00604.1 - 4.2e-12 45.6 0.0 6.5e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain Ntox34 PF15606.6 CCV00604.1 - 0.051 13.7 0.1 0.074 13.2 0.1 1.2 1 0 0 1 1 1 0 Bacterial toxin 34 zf-CCCH_2 PF14608.6 CCV00605.1 - 2e-15 56.6 35.0 4.4e-05 23.8 0.9 5.2 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 CCV00605.1 - 0.0084 15.8 6.1 0.33 10.7 0.1 4.2 4 1 0 4 4 4 2 Putative zinc-finger domain PseudoU_synth_2 PF00849.22 CCV00607.1 - 7.2e-22 78.2 0.0 1.3e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase NIPSNAP PF07978.13 CCV00607.1 - 2.2 8.5 5.4 7.1 6.9 0.3 3.1 3 0 0 3 3 3 0 NIPSNAP Sld7_C PF18596.1 CCV00608.1 - 0.00016 21.7 0.0 0.00034 20.7 0.0 1.6 1 0 0 1 1 1 1 Sld7 C-terminal domain GPP34 PF05719.11 CCV00608.1 - 0.044 13.8 2.3 0.075 13.1 2.3 1.5 1 1 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) MMR_HSR1 PF01926.23 CCV00609.1 - 4.1e-12 46.2 0.0 7.2e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 CCV00609.1 - 0.0045 16.1 0.0 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 CCV00609.1 - 0.0095 15.5 0.1 0.022 14.3 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 CCV00609.1 - 0.07 13.5 0.2 0.25 11.7 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 CCV00609.1 - 0.085 12.9 0.1 0.24 11.4 0.1 1.7 2 0 0 2 2 2 0 Dynamin family AAA_29 PF13555.6 CCV00609.1 - 0.16 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCV00609.1 - 0.19 11.6 0.1 0.74 9.7 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 CCV00609.1 - 0.2 12.1 0.0 0.3 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain MIF4G PF02854.19 CCV00611.1 - 5e-55 186.4 0.6 1.3e-54 185.1 0.6 1.8 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 CCV00611.1 - 1e-18 67.3 0.1 1e-18 67.3 0.1 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 CCV00611.1 - 5.9e-11 42.4 0.3 6.9e-10 38.9 0.0 2.4 2 0 0 2 2 2 1 MA3 domain Plasmodium_HRP PF05403.11 CCV00611.1 - 0.00043 20.2 32.4 0.00043 20.2 32.4 1.7 2 0 0 2 2 2 1 Plasmodium histidine-rich protein (HRPII/III) Bromodomain PF00439.25 CCV00612.1 - 2.5e-07 30.7 0.1 4.7e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 CCV00612.1 - 0.0019 18.2 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated tRNA-synt_2 PF00152.20 CCV00613.1 - 9.2e-78 261.5 0.0 1.6e-77 260.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCV00613.1 - 7.3e-10 38.7 0.0 1.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1682 PF07946.14 CCV00613.1 - 0.0045 16.2 0.6 0.0086 15.3 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4539 PF15072.6 CCV00613.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Peptidase_S8 PF00082.22 CCV00614.1 - 2.8e-32 112.2 5.5 2.8e-32 112.2 5.5 1.5 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 CCV00614.1 - 6.5e-09 36.3 0.0 1.1e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 GIT_SHD PF08518.11 CCV00615.1 - 2.5e-22 78.2 9.1 2.8e-12 46.0 1.8 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF3450 PF11932.8 CCV00615.1 - 0.0059 16.0 5.3 0.0059 16.0 5.3 4.2 4 1 1 5 5 5 2 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 CCV00615.1 - 0.011 15.9 12.3 0.011 15.9 12.3 3.7 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding KASH_CCD PF14662.6 CCV00615.1 - 0.027 14.3 22.2 0.029 14.2 15.0 3.0 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Exonuc_VII_S PF02609.16 CCV00615.1 - 0.14 12.2 0.9 0.38 10.9 0.9 1.7 1 0 0 1 1 1 0 Exonuclease VII small subunit Baculo_PEP_C PF04513.12 CCV00615.1 - 1.4 8.9 15.2 1 9.4 0.1 4.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 CCV00615.1 - 2.1 8.3 30.8 2.2 8.3 5.2 4.3 1 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 CCV00615.1 - 6.7 6.9 15.2 2 8.5 1.4 3.7 3 0 0 3 3 3 0 Basic region leucine zipper Filament PF00038.21 CCV00615.1 - 7.2 6.1 36.5 0.69 9.4 27.5 3.2 3 1 0 3 3 3 0 Intermediate filament protein bZIP_1 PF00170.21 CCV00615.1 - 8.6 6.5 10.2 0.91 9.7 0.9 3.8 3 1 1 4 4 4 0 bZIP transcription factor Mito_carr PF00153.27 CCV00616.1 - 2.4e-66 219.7 1.4 5.3e-21 74.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 CCV00617.1 - 1.1e-28 98.8 0.0 6.8e-09 35.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCV00617.1 - 7.6e-08 32.1 0.0 0.45 10.4 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CCV00617.1 - 0.068 13.2 0.0 4.6 7.3 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CCV00617.1 - 0.14 12.3 0.0 15 5.8 0.0 3.2 4 0 0 4 4 4 0 RNA recognition motif ER_lumen_recept PF00810.18 CCV00618.1 - 4.1e-48 163.9 9.3 5.6e-48 163.5 9.3 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CCV00618.1 - 0.016 15.0 0.3 0.016 15.0 0.3 4.0 5 0 0 5 5 5 0 PQ loop repeat NMO PF03060.15 CCV00619.1 - 1e-42 146.7 5.1 6.4e-41 140.8 5.1 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CCV00619.1 - 7e-07 28.6 1.9 0.00041 19.5 0.0 2.2 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain DUF4364 PF14277.6 CCV00619.1 - 0.047 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DUF1902 PF08972.11 CCV00619.1 - 0.11 12.4 0.1 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Zip PF02535.22 CCV00620.1 - 2.9e-23 82.6 12.4 4e-21 75.6 12.4 2.3 1 1 0 1 1 1 1 ZIP Zinc transporter BCLP PF12304.8 CCV00620.1 - 0.00042 19.9 1.6 0.00088 18.9 1.6 1.5 1 0 0 1 1 1 1 Beta-casein like protein SfLAP PF11139.8 CCV00620.1 - 0.0074 15.8 1.0 0.0074 15.8 1.0 2.3 2 1 0 2 2 2 1 Sap, sulfolipid-1-addressing protein Ribonuclease_T2 PF00445.18 CCV00622.1 - 8.7e-40 136.9 1.2 1.2e-39 136.5 1.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family LHC PF00556.20 CCV00622.1 - 0.016 15.4 0.4 0.028 14.6 0.4 1.4 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit RNA_pol_Rpb1_5 PF04998.17 CCV00623.1 - 5.1e-82 275.3 0.0 8.8e-82 274.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CCV00623.1 - 2.8e-65 219.6 0.1 5e-65 218.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CCV00623.1 - 3.7e-35 121.2 0.0 7.1e-35 120.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CCV00623.1 - 2.6e-27 96.0 0.0 5.4e-24 85.1 0.0 2.9 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 CCV00623.1 - 1.8e-19 69.7 0.0 4.4e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 TrwC PF08751.11 CCV00623.1 - 0.026 14.0 0.8 0.071 12.6 0.1 2.1 2 0 0 2 2 2 0 TrwC relaxase LcrG PF07216.12 CCV00623.1 - 0.12 12.4 4.0 0.09 12.7 0.3 2.7 3 0 0 3 3 3 0 LcrG protein ThiF PF00899.21 CCV00624.1 - 7.2e-39 133.6 0.0 1.1e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family FAD_binding_3 PF01494.19 CCV00624.1 - 0.016 14.4 0.2 0.027 13.7 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 CCV00624.1 - 0.22 11.2 0.2 0.41 10.3 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CcmD PF04995.14 CCV00624.1 - 0.92 9.6 6.8 3.2 7.9 6.8 2.0 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) 6PF2K PF01591.18 CCV00625.1 - 2.5e-69 233.0 0.0 3.4e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CCV00625.1 - 1.2e-33 116.5 0.0 2.5e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CCV00625.1 - 1.4e-06 28.5 0.4 2.7e-06 27.6 0.4 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CCV00625.1 - 0.006 16.1 0.0 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 GBP PF02263.19 CCV00625.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_17 PF13207.6 CCV00625.1 - 0.086 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_M24 PF00557.24 CCV00626.1 - 3.9e-40 137.8 0.1 5.2e-40 137.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 RNA_polI_A34 PF08208.11 CCV00626.1 - 0.053 13.6 10.6 0.075 13.1 10.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Coilin_N PF15862.5 CCV00626.1 - 1 9.1 7.4 4.3 7.1 6.8 2.0 2 0 0 2 2 2 0 Coilin N-terminus Cnd2 PF05786.14 CCV00626.1 - 1.4 7.5 12.3 0.54 8.9 9.9 1.4 2 0 0 2 2 2 0 Condensin complex subunit 2 CDC45 PF02724.14 CCV00626.1 - 1.8 6.8 8.6 2.5 6.3 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 CCV00626.1 - 3.6 8.0 10.0 8.7 6.8 10.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.12 CCV00626.1 - 7.3 6.6 16.7 1.7 8.7 12.5 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 UQ_con PF00179.26 CCV00627.1 - 6.8e-35 119.8 0.0 7.3e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rhodanese PF00581.20 CCV00628.1 - 1.3e-16 61.1 0.0 3.2e-09 37.3 0.0 2.9 2 1 0 2 2 2 2 Rhodanese-like domain ThiC-associated PF13667.6 CCV00628.1 - 0.2 11.5 0.0 0.89 9.4 0.0 2.1 2 0 0 2 2 2 0 ThiC-associated domain Arrestin_C PF02752.22 CCV00629.1 - 5.4e-17 62.5 0.0 9.3e-14 52.0 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCV00629.1 - 2.6e-13 50.3 0.0 1.2e-09 38.3 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CCV00629.1 - 3.8e-06 26.7 0.0 7.4e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Arrestin_N terminal like Rgp1 PF08737.10 CCV00629.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Rgp1 Nup192 PF11894.8 CCV00630.1 - 1.2e-08 32.7 0.0 1.7e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 CCV00630.1 - 0.00029 18.9 0.0 0.14 10.0 0.0 3.4 4 0 0 4 4 4 3 Nucleoporin subcomplex protein binding to Pom34 Macro PF01661.21 CCV00631.1 - 4e-11 43.0 0.0 9.8e-11 41.7 0.0 1.6 2 0 0 2 2 2 1 Macro domain ANF_receptor PF01094.28 CCV00631.1 - 0.087 11.9 0.0 0.13 11.3 0.0 1.3 1 1 0 1 1 1 0 Receptor family ligand binding region Romo1 PF10247.9 CCV00632.1 - 3.6e-22 78.5 15.6 4.4e-22 78.2 15.6 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Methyltransf_12 PF08242.12 CCV00633.1 - 4.2e-10 40.3 0.0 1.1e-09 38.9 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCV00633.1 - 1.4e-08 34.8 0.0 2.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCV00633.1 - 4.6e-07 30.5 0.0 1.8e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCV00633.1 - 9.1e-05 22.1 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CCV00633.1 - 0.0015 19.2 0.0 0.0046 17.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCV00633.1 - 0.0031 17.3 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Nucleoporin_C PF03177.14 CCV00634.1 - 9.2e-58 196.4 9.5 8.3e-57 193.3 4.4 2.7 2 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 CCV00634.1 - 6.9e-05 21.8 0.0 0.00013 20.9 0.0 1.4 1 1 0 1 1 1 1 Nup133 N terminal like DUF1682 PF07946.14 CCV00635.1 - 1.8e-48 165.4 0.0 2e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) USP7_ICP0_bdg PF12436.8 CCV00636.1 - 6.5e-82 274.4 1.6 1.4e-81 273.4 0.3 2.0 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 CCV00636.1 - 3e-62 210.0 6.3 2.4e-61 207.1 0.7 3.2 3 1 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 CCV00636.1 - 5.4e-49 167.0 1.7 6.4e-49 166.7 0.2 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCV00636.1 - 2.9e-23 83.0 0.0 2.1e-22 80.1 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 CCV00636.1 - 3.5e-10 40.0 0.0 3.4e-09 36.8 0.0 2.5 2 0 0 2 2 2 1 MATH domain Acetyltransf_1 PF00583.25 CCV00637.1 - 9e-13 48.5 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCV00637.1 - 3.6e-09 36.6 0.0 5.9e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCV00637.1 - 1.9e-08 34.6 0.0 2.8e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CCV00637.1 - 0.056 13.6 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 CCV00637.1 - 0.11 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 CCV00637.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Chalcone_2 PF16035.5 CCV00638.1 - 5.7e-32 111.2 0.3 5.6e-29 101.4 0.3 2.2 1 1 0 1 1 1 1 Chalcone isomerase like Abhydrolase_1 PF00561.20 CCV00638.1 - 1.7e-16 60.7 0.0 3.1e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCV00638.1 - 1.6e-12 48.5 2.7 1.7e-12 48.4 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCV00638.1 - 2.8e-10 39.9 0.1 5.4e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CCV00638.1 - 3.4e-07 30.2 0.7 1.6e-05 24.8 0.7 2.2 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 CCV00638.1 - 5.5e-06 26.7 0.0 8.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Chalcone_3 PF16036.5 CCV00638.1 - 5.6e-06 26.6 0.0 5.1e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Chalcone isomerase-like DUF676 PF05057.14 CCV00638.1 - 4.7e-05 23.0 0.0 7.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CCV00638.1 - 0.00036 20.5 0.0 0.00067 19.6 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 CCV00638.1 - 0.00074 18.5 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 CCV00638.1 - 0.00075 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Lipase_3 PF01764.25 CCV00638.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) LCAT PF02450.15 CCV00638.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 CCV00638.1 - 0.099 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Arrestin_N PF00339.29 CCV00639.1 - 1.8e-05 24.8 0.1 0.28 11.3 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain PerB PF06590.11 CCV00641.1 - 0.0072 16.8 0.1 2.7 8.5 0.0 2.2 2 0 0 2 2 2 2 PerB protein DUF1433 PF07252.11 CCV00641.1 - 0.026 14.8 0.0 7.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1433) CaM-KIIN PF15170.6 CCV00641.1 - 0.13 12.4 0.9 21 5.4 0.1 2.4 2 0 0 2 2 2 0 Calcium/calmodulin-dependent protein kinase II inhibitor AcylCoA_DH_N PF12418.8 CCV00641.1 - 0.3 11.2 0.4 33 4.6 0.1 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase N terminal DUF4148 PF13663.6 CCV00641.1 - 0.71 10.1 6.7 4.4 7.6 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) Asp PF00026.23 CCV00642.1 - 1.4e-47 162.7 2.3 3.7e-47 161.3 2.3 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCV00642.1 - 1.5e-07 31.8 0.4 0.00021 21.6 0.4 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CCV00642.1 - 0.00044 20.1 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CCV00642.1 - 0.00051 20.6 0.1 1.1 10.0 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CCV00642.1 - 0.0023 18.4 0.1 1.9 9.1 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease CclA_1 PF16942.5 CCV00642.1 - 0.037 14.3 0.0 0.092 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative cyclic bacteriocin Xin PF08043.12 CCV00643.1 - 0.17 11.5 0.5 0.51 10.1 0.5 1.9 1 0 0 1 1 1 0 Xin repeat CactinC_cactus PF09732.9 CCV00645.1 - 5.8e-57 191.0 5.0 8.7e-57 190.5 5.0 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 CCV00645.1 - 2.5e-47 161.2 1.4 4.4e-47 160.4 1.4 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin AD PF09793.9 CCV00646.1 - 2.7e-12 46.6 0.0 4.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain L51_S25_CI-B8 PF05047.16 CCV00647.1 - 1.7e-06 27.8 0.0 2.2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain eRF1_1 PF03463.15 CCV00648.1 - 7.3e-54 181.2 0.0 1.4e-53 180.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 CCV00648.1 - 1.7e-21 76.8 0.0 2.8e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 CCV00648.1 - 3.8e-17 62.9 0.0 5.5e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 2 Spc7 PF08317.11 CCV00649.1 - 0.017 14.0 11.4 0.035 13.0 11.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 CCV00649.1 - 0.19 11.8 2.6 0.34 11.0 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 CCV00649.1 - 0.2 11.0 7.8 0.32 10.3 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V-SNARE PF05008.15 CCV00649.1 - 0.23 11.9 3.2 1.1 9.6 2.1 2.4 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus FH2 PF02181.23 CCV00649.1 - 0.51 9.4 3.2 0.86 8.7 3.2 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain COG2 PF06148.11 CCV00649.1 - 2.6 8.1 4.4 6.1 6.9 4.4 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FAM184 PF15665.5 CCV00649.1 - 3.5 7.3 17.3 1.7 8.3 12.5 2.4 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B HCO3_cotransp PF00955.21 CCV00651.1 - 4.3e-50 171.0 15.0 3.1e-23 82.4 0.2 3.1 2 1 1 3 3 3 3 HCO3- transporter family RNA_pol_Rpb4 PF03874.16 CCV00652.1 - 1.4e-23 83.6 0.1 1.8e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Ribosomal_S18 PF01084.20 CCV00653.1 - 2.9e-19 69.0 0.0 4.8e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 HK PF02110.15 CCV00654.1 - 7.2e-64 215.5 3.2 6.1e-61 205.9 5.2 2.2 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 CCV00654.1 - 3.9e-39 133.8 0.0 7.1e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 CCV00654.1 - 0.00066 19.1 0.5 0.0011 18.5 0.5 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Sld5 PF05916.11 CCV00655.1 - 1.5e-06 28.6 0.3 1.8e-06 28.4 0.3 1.1 1 0 0 1 1 1 1 GINS complex protein Sec10 PF07393.11 CCV00656.1 - 8e-220 732.0 0.0 9.7e-220 731.7 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Tropomyosin_1 PF12718.7 CCV00656.1 - 0.019 15.1 0.7 0.039 14.1 0.7 1.5 1 0 0 1 1 1 0 Tropomyosin like Glyco_transf_18 PF15024.6 CCV00656.1 - 0.034 12.7 0.4 0.065 11.8 0.1 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 18 FAM184 PF15665.5 CCV00656.1 - 0.05 13.4 1.9 0.12 12.1 1.9 1.6 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Sec34 PF04136.15 CCV00656.1 - 0.069 13.0 1.4 0.18 11.7 0.2 2.2 1 1 1 2 2 2 0 Sec34-like family DUF4158 PF13700.6 CCV00656.1 - 0.12 12.2 1.3 0.33 10.8 1.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) DisA-linker PF10635.9 CCV00656.1 - 0.12 12.1 1.0 0.33 10.7 1.0 1.7 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region V_ATPase_I PF01496.19 CCV00656.1 - 0.56 8.1 3.3 5.6 4.8 2.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF5082 PF16888.5 CCV00656.1 - 1.1 9.5 4.2 7.5 6.9 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) RIX1 PF08167.12 CCV00657.1 - 2.9e-10 40.2 0.2 7.3e-10 38.9 0.2 1.7 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Pex2_Pex12 PF04757.14 CCV00658.1 - 3.6e-32 111.8 10.1 5.2e-32 111.2 10.1 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Acid_PPase PF12689.7 CCV00659.1 - 1.5e-15 57.5 0.1 1.6e-15 57.4 0.1 1.0 1 0 0 1 1 1 1 Acid Phosphatase Acid_PPase PF12689.7 CCV00660.1 - 0.0032 17.3 0.0 0.0039 17.0 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase Hist_deacetyl PF00850.19 CCV00661.1 - 2.5e-81 273.5 0.0 3.2e-81 273.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain TPR_2 PF07719.17 CCV00662.1 - 1.7e-15 55.8 5.2 2.8 8.3 0.0 9.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 CCV00662.1 - 1.1e-14 54.8 7.1 0.0022 18.6 0.1 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 CCV00662.1 - 1.7e-13 49.8 7.5 0.079 12.8 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCV00662.1 - 2.4e-12 47.2 9.2 0.00057 20.3 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCV00662.1 - 1e-10 41.5 12.3 0.0015 19.1 0.3 8.9 6 2 3 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCV00662.1 - 3.8e-09 36.0 0.2 1.9 8.9 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 CCV00662.1 - 1e-08 35.3 6.4 5.8 7.8 0.0 8.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCV00662.1 - 4.5e-08 33.3 3.4 0.038 14.3 0.0 6.1 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 CCV00662.1 - 2.5e-07 30.7 7.8 0.011 15.9 0.6 6.9 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCV00662.1 - 5.7e-06 25.9 0.1 0.56 9.9 0.0 5.1 4 1 1 5 5 5 2 TPR repeat TPR_17 PF13431.6 CCV00662.1 - 5.8e-05 23.2 0.0 12 6.5 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCV00662.1 - 0.00031 20.9 5.0 8.3 6.7 0.0 5.8 5 2 2 7 7 6 1 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 CCV00662.1 - 0.0016 18.9 0.3 1 9.8 0.0 2.6 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation TPR_20 PF14561.6 CCV00662.1 - 0.006 16.9 6.4 1.9 8.8 0.1 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 CCV00662.1 - 0.0071 15.6 1.7 0.47 9.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCV00662.1 - 0.019 15.0 6.1 3 8.1 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat HEPN PF05168.14 CCV00662.1 - 0.24 11.5 1.5 19 5.4 0.0 3.5 3 0 0 3 3 3 0 HEPN domain WBS_methylT PF12589.8 CCV00663.1 - 8.6e-20 71.3 5.0 1.4e-19 70.6 5.0 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 CCV00663.1 - 1e-09 38.9 0.0 2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCV00663.1 - 5.2e-08 33.5 0.0 9.8e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCV00663.1 - 2.7e-05 24.1 0.0 4.5e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCV00663.1 - 8.5e-05 23.2 0.4 0.00085 20.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCV00663.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 CCV00663.1 - 0.0071 16.7 0.0 0.02 15.2 0.0 1.7 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase N6_N4_Mtase PF01555.18 CCV00663.1 - 0.013 15.2 0.0 0.053 13.2 0.0 1.8 2 0 0 2 2 2 0 DNA methylase TehB PF03848.14 CCV00663.1 - 0.077 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 CCV00663.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Syntaxin-18_N PF10496.9 CCV00664.1 - 2.1e-14 53.5 0.1 1.1e-13 51.2 0.0 2.4 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus PSK_trans_fac PF07704.11 CCV00664.1 - 3.6 8.4 9.7 13 6.6 1.8 2.7 2 0 0 2 2 2 0 Rv0623-like transcription factor TipAS PF07739.13 CCV00664.1 - 9.6 6.8 9.2 0.67 10.5 1.5 2.5 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain BCDHK_Adom3 PF10436.9 CCV00665.1 - 1.2e-24 87.0 5.4 2.1e-24 86.2 5.4 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Pkinase PF00069.25 CCV00666.1 - 1.5e-72 244.1 0.0 2.9e-72 243.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCV00666.1 - 2.4e-32 112.2 0.0 6.3e-32 110.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCV00666.1 - 7e-05 22.3 0.5 0.49 9.7 0.0 3.5 3 1 0 3 3 3 2 Kinase-like APH PF01636.23 CCV00666.1 - 0.00059 19.8 0.7 0.6 10.0 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 CCV00666.1 - 0.00064 19.4 0.2 0.0013 18.4 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CCV00666.1 - 0.051 12.4 0.0 0.092 11.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Sua5_yciO_yrdC PF01300.18 CCV00667.1 - 2.3e-51 173.8 0.0 3.3e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CCV00667.1 - 3.3e-31 108.6 0.0 5.2e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding AMP-binding PF00501.28 CCV00668.1 - 1.2e-72 244.9 0.0 1.7e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CCV00668.1 - 5e-69 232.3 0.0 1.8e-68 230.5 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 CCV00668.1 - 8e-11 42.1 0.0 2.1e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 CCV00668.1 - 9.6e-11 41.0 0.0 3.1e-09 36.0 0.0 2.7 1 1 0 1 1 1 1 Condensation domain Epimerase PF01370.21 CCV00668.1 - 3.8e-10 39.6 0.1 7.1e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCV00668.1 - 3.8e-07 29.4 0.0 1.1e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 CCV00668.1 - 0.00053 20.9 2.1 0.0026 18.7 0.1 3.4 3 1 0 3 3 3 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.17 CCV00668.1 - 0.028 13.5 1.8 0.11 11.5 0.0 2.3 3 0 0 3 3 3 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 CCV00668.1 - 0.46 10.4 3.7 3.5 7.5 3.7 2.4 1 1 0 1 1 1 0 NAD(P)H-binding VCBS PF13517.6 CCV00669.1 - 7.9e-17 61.6 8.0 0.0012 19.4 0.0 5.2 5 1 1 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CCV00669.1 - 5.3e-09 36.0 1.0 1.5 9.0 0.1 5.7 5 0 0 5 5 5 3 FG-GAP repeat EF-hand_5 PF13202.6 CCV00669.1 - 2 8.1 8.7 0.69 9.5 0.1 3.3 4 0 0 4 4 4 0 EF hand V_ATPase_I PF01496.19 CCV00670.1 - 0 1020.9 0.0 0 1020.7 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family BioW PF03744.13 CCV00670.1 - 0.12 11.9 0.1 0.36 10.3 0.1 1.7 2 0 0 2 2 2 0 6-carboxyhexanoate--CoA ligase RisS_PPD PF16524.5 CCV00670.1 - 0.14 12.4 0.3 0.35 11.1 0.3 1.6 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS Spc24 PF08286.11 CCV00670.1 - 1.1 9.5 4.0 0.57 10.4 1.0 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PRP21_like_P PF12230.8 CCV00672.1 - 1.4e-35 123.2 1.2 1.2e-16 61.2 0.0 2.4 1 1 1 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CCV00672.1 - 6.4e-34 115.7 3.9 1.2e-18 66.9 0.2 2.4 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 CCV00672.1 - 0.038 13.6 0.1 0.07 12.7 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Glyco_hydro_46 PF01374.18 CCV00672.1 - 0.12 11.9 1.8 0.26 10.9 1.8 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 zf-Di19 PF05605.12 CCV00672.1 - 0.15 12.4 1.3 0.31 11.4 0.1 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PalH PF08733.10 CCV00672.1 - 1 8.3 5.6 1.6 7.7 5.6 1.3 1 0 0 1 1 1 0 PalH/RIM21 Chorismate_bind PF00425.18 CCV00673.1 - 3.8e-90 301.9 0.0 5.5e-90 301.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 CCV00673.1 - 5.1e-24 85.1 0.0 2.6e-23 82.8 0.0 2.2 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region ComZ PF10815.8 CCV00674.1 - 0.062 13.3 0.1 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 ComZ Lipase_3 PF01764.25 CCV00675.1 - 5.5e-07 29.5 0.0 9.5e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 CCV00675.1 - 0.035 13.9 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.12 CCV00675.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) VirB8 PF04335.13 CCV00675.1 - 0.12 12.2 0.8 0.18 11.6 0.8 1.3 1 0 0 1 1 1 0 VirB8 protein PGAP1 PF07819.13 CCV00675.1 - 0.2 11.4 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein GCV_H PF01597.19 CCV00676.1 - 5.3e-15 55.4 0.0 6.4e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Ribosomal_S19 PF00203.21 CCV00677.1 - 5.1e-28 96.8 0.1 6.3e-28 96.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 POB3_N PF17292.2 CCV00678.1 - 1.1e-23 83.4 0.0 1.1e-19 70.6 0.0 2.5 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 CCV00678.1 - 1.5e-23 82.5 0.0 3.4e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 CCV00678.1 - 4.4e-23 81.5 0.2 7e-22 77.7 0.0 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PRK PF00485.18 CCV00678.1 - 0.00024 20.9 0.2 0.0036 17.1 0.2 2.2 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family TIP41 PF04176.13 CCV00678.1 - 0.17 11.3 0.1 0.38 10.2 0.1 1.5 1 0 0 1 1 1 0 TIP41-like family RNA_pol_Rpc4 PF05132.14 CCV00678.1 - 9.3 6.7 8.1 9.1 6.7 0.9 2.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 TANGO2 PF05742.12 CCV00679.1 - 2.7e-46 158.7 0.0 3e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Arrestin_C PF02752.22 CCV00681.1 - 7.3e-05 23.2 0.5 0.00022 21.7 0.3 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCV00681.1 - 0.0062 16.6 0.0 0.61 10.1 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain MG2 PF01835.19 CCV00681.1 - 0.078 13.4 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 MG2 domain Ribonuc_red_lgC PF02867.15 CCV00682.1 - 1.1e-185 618.2 0.0 1.8e-185 617.4 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CCV00682.1 - 5e-24 84.1 0.3 4.2e-23 81.1 0.1 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CCV00682.1 - 8.4e-15 55.1 0.2 1.8e-14 54.1 0.2 1.6 1 0 0 1 1 1 1 ATP cone domain MARVEL PF01284.23 CCV00683.1 - 8e-12 45.4 15.5 1.1e-11 44.9 15.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain MscS_TM PF12794.7 CCV00683.1 - 0.029 13.2 3.6 0.049 12.5 3.6 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Yip1 PF04893.17 CCV00683.1 - 5.5 6.7 23.3 1e+03 -0.7 8.1 2.2 1 1 0 1 1 1 0 Yip1 domain Brix PF04427.18 CCV00684.1 - 9.9e-37 126.9 0.0 1.4e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain WD40 PF00400.32 CCV00685.1 - 5.6e-18 65.0 4.3 0.0077 17.1 0.3 5.9 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCV00685.1 - 0.016 15.5 0.0 0.78 10.1 0.2 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCV00685.1 - 0.039 12.6 0.1 0.091 11.4 0.1 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 CCV00685.1 - 0.84 10.2 3.3 2.7 8.6 0.1 3.4 4 0 0 4 4 4 0 PQQ-like domain Methyltransf_16 PF10294.9 CCV00686.1 - 4e-11 43.0 0.0 7.2e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase DNA_processg_A PF02481.15 CCV00686.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A Methyltransf_23 PF13489.6 CCV00686.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CCV00686.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PTCB-BRCT PF12738.7 CCV00687.1 - 7.7e-19 67.4 0.0 5.4e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 twin BRCT domain BRCT PF00533.26 CCV00687.1 - 1.2e-12 48.0 0.0 4.5e-07 30.2 0.0 2.4 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CCV00687.1 - 4.3e-06 27.0 0.0 0.038 14.4 0.0 2.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain YL1 PF05764.13 CCV00688.1 - 8.9e-42 143.9 21.4 1.5e-41 143.1 21.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 CCV00688.1 - 3.9e-15 55.3 0.1 7.1e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ly49 PF08391.10 CCV00688.1 - 0.3 11.5 0.6 0.5 10.7 0.6 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF4632 PF15451.6 CCV00688.1 - 2 8.6 7.6 7.3 6.8 7.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Ribonuc_red_sm PF00268.21 CCV00689.1 - 1.2e-120 402.2 0.8 1.5e-120 401.9 0.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Cellulase PF00150.18 CCV00690.1 - 8.8e-18 64.7 2.3 1.5e-17 63.9 2.3 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SPX PF03105.19 CCV00690.1 - 6.4e-05 23.0 30.4 0.0057 16.6 11.8 2.3 2 0 0 2 2 2 2 SPX domain Apt1 PF10351.9 CCV00690.1 - 0.0017 17.3 14.5 0.0017 17.3 14.5 2.3 2 0 0 2 2 2 2 Golgi-body localisation protein domain Plasmodium_HRP PF05403.11 CCV00690.1 - 0.045 13.5 22.4 0.079 12.7 22.4 1.3 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) DUF572 PF04502.13 CCV00690.1 - 0.34 10.5 20.5 0.6 9.7 7.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) SOG2 PF10428.9 CCV00690.1 - 0.38 9.9 47.9 1 8.5 20.5 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Utp14 PF04615.13 CCV00690.1 - 0.65 8.5 19.7 0.44 9.1 6.4 2.2 2 0 0 2 2 2 0 Utp14 protein Macoilin PF09726.9 CCV00690.1 - 1.1 7.7 45.2 0.027 13.1 19.1 2.2 2 0 0 2 2 2 0 Macoilin family Pkinase_fungal PF17667.1 CCV00690.1 - 2.3 6.9 16.2 0.92 8.2 7.3 2.3 2 0 0 2 2 2 0 Fungal protein kinase Velvet PF11754.8 CCV00690.1 - 6.7 6.6 32.2 1.9 8.4 10.7 2.3 2 0 0 2 2 2 0 Velvet factor BUD22 PF09073.10 CCV00690.1 - 8.5 5.6 32.5 2 7.7 6.3 2.2 2 0 0 2 2 2 0 BUD22 CAP_N PF01213.19 CCV00691.1 - 1.9e-107 359.4 3.4 1.9e-107 359.4 3.4 2.0 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CCV00691.1 - 2.6e-57 192.8 0.3 4e-57 192.2 0.3 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Ndc80_HEC PF03801.13 CCV00691.1 - 1.1e-29 103.0 0.0 4.2e-29 101.1 0.0 1.9 2 0 0 2 2 2 1 HEC/Ndc80p family DUF5595 PF18077.1 CCV00691.1 - 3.7e-12 46.2 0.4 3.7e-12 46.2 0.4 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF5595) TBCC PF07986.12 CCV00691.1 - 0.0022 17.7 1.2 0.0042 16.8 1.2 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C HALZ PF02183.18 CCV00691.1 - 0.0035 17.5 8.8 0.2 11.9 1.0 3.4 3 0 0 3 3 3 2 Homeobox associated leucine zipper DUF5082 PF16888.5 CCV00691.1 - 3.3 8.0 8.2 6.6 7.0 3.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Pex2_Pex12 PF04757.14 CCV00693.1 - 2.9e-46 157.9 10.1 3.5e-46 157.6 10.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CCV00693.1 - 0.0013 18.6 3.3 0.002 17.9 3.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCV00693.1 - 0.085 13.2 3.0 0.15 12.4 3.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 CCV00693.1 - 3.2 7.7 6.4 15 5.5 6.3 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Thg1C PF14413.6 CCV00694.1 - 1e-21 77.3 0.9 9.3e-17 61.3 0.0 2.6 1 1 2 3 3 3 2 Thg1 C terminal domain CG-1 PF03859.16 CCV00694.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 CG-1 domain SUIM_assoc PF16619.5 CCV00695.1 - 0.042 13.9 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 UQ_con PF00179.26 CCV00696.1 - 2.9e-07 30.2 0.1 3.8e-07 29.8 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme STAG PF08514.11 CCV00698.1 - 1.9e-26 92.2 0.7 1.3e-25 89.5 0.1 2.6 2 0 0 2 2 2 1 STAG domain Cnd1 PF12717.7 CCV00698.1 - 0.0013 18.8 0.5 4.6 7.3 0.1 4.3 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CCV00698.1 - 0.007 16.5 0.7 8.7 6.9 0.0 4.8 3 0 0 3 3 3 1 HEAT repeat BLOC1_2 PF10046.9 CCV00698.1 - 1.8 9.0 5.7 0.63 10.4 0.6 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ipi1_N PF12333.8 CCV00699.1 - 2.9e-17 63.1 2.7 8.1e-17 61.7 0.0 3.1 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.6 CCV00699.1 - 0.05 14.0 1.0 1.8 9.0 0.2 3.6 2 1 1 3 3 3 0 HEAT repeats Transp_cyt_pur PF02133.15 CCV00700.1 - 1.3e-29 103.3 36.0 1.8e-29 102.8 36.0 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MIG-14_Wnt-bd PF06664.12 CCV00700.1 - 0.21 10.8 15.6 0.025 13.8 1.3 2.4 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion Cellulase PF00150.18 CCV00701.1 - 5.7e-18 65.3 4.9 8.8e-18 64.7 4.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LETM1 PF07766.13 CCV00703.1 - 5.5e-94 314.5 1.8 5.5e-94 314.5 1.8 2.2 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 CCV00703.1 - 4.5e-05 23.8 3.3 0.00085 19.7 0.1 3.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 CCV00703.1 - 0.0011 18.7 0.0 0.0043 16.9 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CCV00703.1 - 0.16 12.0 0.1 7.3 6.8 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain NUC173 PF08161.12 CCV00704.1 - 5.6e-54 182.9 0.1 4.5e-53 179.9 0.0 2.3 2 0 0 2 2 2 1 NUC173 domain Tti2 PF10521.9 CCV00704.1 - 0.11 12.0 0.1 6.7 6.2 0.0 3.0 2 1 1 3 3 3 0 Tti2 family Ferric_reduct PF01794.19 CCV00705.1 - 8.5e-17 61.4 10.5 8.5e-17 61.4 10.5 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CCV00705.1 - 9.3e-13 48.6 0.0 2.9e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CCV00705.1 - 2.3e-10 40.5 0.0 1.1e-08 35.1 0.0 3.0 2 1 0 2 2 2 1 FAD-binding domain Gpi16 PF04113.14 CCV00706.1 - 3.4e-109 365.8 0.0 1.2e-106 357.4 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Rot1 PF10681.9 CCV00707.1 - 5.6e-49 166.5 4.7 7.7e-49 166.0 4.7 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal GAS2 PF02187.17 CCV00707.1 - 0.052 13.7 0.9 0.15 12.2 0.1 2.0 2 0 0 2 2 2 0 Growth-Arrest-Specific Protein 2 Domain Coatomer_WDAD PF04053.14 CCV00708.1 - 3.2e-123 412.1 0.0 5.3e-123 411.4 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 CCV00708.1 - 1.8e-84 283.9 0.0 2.4e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CCV00708.1 - 3e-43 145.0 12.8 3.8e-08 33.9 0.1 8.1 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCV00708.1 - 5.8e-13 48.9 1.7 0.0013 19.0 0.0 5.7 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCV00708.1 - 0.00014 20.6 9.7 0.0059 15.3 0.4 4.2 2 1 3 5 5 5 2 Nucleoporin Nup120/160 Mit_ribos_Mrp51 PF11709.8 CCV00709.1 - 1.4e-16 61.1 0.0 2.5e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit DMRL_synthase PF00885.19 CCV00710.1 - 7e-54 181.5 0.0 7.8e-54 181.3 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase ECH_2 PF16113.5 CCV00711.1 - 7.6e-90 301.8 0.0 3.9e-89 299.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CCV00711.1 - 1.3e-15 57.5 0.5 3.6e-14 52.7 0.1 2.7 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase tRNA-synt_2 PF00152.20 CCV00712.1 - 1.4e-35 122.9 0.0 1.9e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCV00712.1 - 2.2e-05 24.3 0.1 3.5e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain D123 PF07065.14 CCV00713.1 - 1.3e-86 290.5 0.0 1.6e-86 290.3 0.0 1.0 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 CCV00713.1 - 0.0017 18.4 0.0 0.0041 17.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 CCV00713.1 - 0.07 13.0 0.2 0.2 11.5 0.0 1.8 3 0 0 3 3 3 0 ATP-grasp domain, R2K clade family 2 EBV-NA3 PF05009.12 CCV00713.1 - 0.1 12.1 0.2 0.23 11.0 0.1 1.6 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RRM_1 PF00076.22 CCV00714.1 - 2e-12 46.7 0.1 7e-12 45.0 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3602 PF12223.8 CCV00714.1 - 0.22 12.2 7.2 0.11 13.1 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3602) NAC PF01849.18 CCV00715.1 - 4.2e-22 77.9 0.2 7.1e-22 77.1 0.2 1.4 1 0 0 1 1 1 1 NAC domain ATP-synt_E PF05680.12 CCV00716.1 - 1e-19 70.7 0.5 1.2e-19 70.4 0.5 1.2 1 1 0 1 1 1 1 ATP synthase E chain AMP-binding PF00501.28 CCV00717.1 - 4.5e-92 308.8 0.0 5.3e-92 308.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCV00717.1 - 8.8e-24 84.3 0.2 4.4e-23 82.0 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CCV00717.1 - 1.1e-14 54.0 0.1 2.4e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus She9_MDM33 PF05546.11 CCV00718.1 - 2.4e-53 180.9 6.6 2.9e-53 180.6 6.6 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family Med21 PF11221.8 CCV00718.1 - 1.8 8.8 6.8 1.3 9.3 3.2 2.2 2 1 0 2 2 2 0 Subunit 21 of Mediator complex ABC_tran PF00005.27 CCV00719.1 - 2.6e-42 144.6 0.0 4.5e-21 75.8 0.0 4.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CCV00719.1 - 2.3e-15 57.2 2.0 0.00042 20.2 0.0 4.3 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCV00719.1 - 9e-13 48.2 0.7 0.025 14.0 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCV00719.1 - 2e-08 33.9 0.3 0.0053 16.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain CLASP_N PF12348.8 CCV00719.1 - 1.9e-07 30.9 0.0 0.012 15.2 0.0 2.7 1 1 1 2 2 2 2 CLASP N terminal Cnd1 PF12717.7 CCV00719.1 - 1e-06 28.9 0.7 0.02 14.9 0.3 3.5 1 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 AAA_22 PF13401.6 CCV00719.1 - 3.2e-06 27.5 0.4 0.21 11.9 0.0 4.9 6 0 0 6 6 5 1 AAA domain AAA_18 PF13238.6 CCV00719.1 - 0.00023 21.7 0.0 0.39 11.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCV00719.1 - 0.00026 21.4 0.1 0.36 11.2 0.0 3.5 3 1 1 4 4 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 CCV00719.1 - 0.00028 20.8 0.0 0.62 9.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase HEAT_EZ PF13513.6 CCV00719.1 - 0.00049 20.5 1.5 3.5 8.2 0.0 5.4 5 1 1 6 6 4 1 HEAT-like repeat NACHT PF05729.12 CCV00719.1 - 0.00059 19.8 0.2 1.4 8.8 0.0 3.1 3 0 0 3 3 2 1 NACHT domain 4HB PF17947.1 CCV00719.1 - 0.0006 19.8 0.0 0.0027 17.8 0.0 2.2 1 0 0 1 1 1 1 Four helical bundle domain MMR_HSR1 PF01926.23 CCV00719.1 - 0.00063 19.8 0.1 1.3 9.1 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 CCV00719.1 - 0.0014 17.9 0.0 0.2 10.8 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_15 PF13175.6 CCV00719.1 - 0.0014 18.4 3.1 0.21 11.3 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 CCV00719.1 - 0.0015 18.8 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CCV00719.1 - 0.0019 17.5 0.1 1.5 7.9 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain AAA_33 PF13671.6 CCV00719.1 - 0.0019 18.4 0.0 1.9 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CCV00719.1 - 0.0019 18.7 0.0 0.012 16.2 0.0 3.9 4 1 0 4 4 2 2 AAA domain AAA PF00004.29 CCV00719.1 - 0.0025 18.2 0.0 2.6 8.5 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 CCV00719.1 - 0.0031 16.5 0.2 0.4 9.6 0.0 2.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB EF-hand_7 PF13499.6 CCV00719.1 - 0.0033 17.8 0.2 0.3 11.6 0.0 3.3 3 0 0 3 3 2 1 EF-hand domain pair RNA_helicase PF00910.22 CCV00719.1 - 0.0041 17.5 0.0 6.1 7.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Chromo PF00385.24 CCV00719.1 - 0.0046 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HEAT_2 PF13646.6 CCV00719.1 - 0.0048 17.3 2.3 3.9 7.9 0.0 4.5 4 1 1 5 5 4 1 HEAT repeats AAA_30 PF13604.6 CCV00719.1 - 0.0071 16.1 0.1 10 5.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain HEAT PF02985.22 CCV00719.1 - 0.011 15.9 2.1 28 5.3 0.0 5.8 7 0 0 7 7 6 0 HEAT repeat DUF87 PF01935.17 CCV00719.1 - 0.014 15.5 7.5 0.21 11.6 0.1 4.0 4 0 0 4 4 3 0 Helicase HerA, central domain AAA_24 PF13479.6 CCV00719.1 - 0.04 13.6 0.0 3.7 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 CCV00719.1 - 0.056 13.2 0.3 5.1 6.8 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 CCV00719.1 - 0.067 13.1 0.1 7.7 6.4 0.0 2.6 2 0 0 2 2 2 0 NTPase Roc PF08477.13 CCV00719.1 - 0.068 13.4 0.0 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase UME PF08064.13 CCV00719.1 - 0.069 13.1 0.9 3.3 7.7 0.7 2.8 2 1 1 3 3 3 0 UME (NUC010) domain SbcCD_C PF13558.6 CCV00719.1 - 0.072 13.3 1.1 1.8 8.9 0.1 3.5 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 CCV00719.1 - 0.074 12.6 0.0 7.2 6.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 CCV00719.1 - 0.078 12.3 0.2 21 4.3 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family Peroxidase_2 PF01328.17 CCV00719.1 - 0.1 13.1 0.1 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 Peroxidase, family 2 AAA_14 PF13173.6 CCV00719.1 - 0.12 12.4 0.0 38 4.3 0.0 4.2 4 1 0 4 4 4 0 AAA domain AAA_7 PF12775.7 CCV00719.1 - 0.12 11.8 0.1 15 5.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 CCV00719.1 - 0.25 11.3 2.1 31 4.6 0.0 4.1 5 0 0 5 5 3 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 CCV00719.1 - 0.29 9.7 4.4 1.5 7.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 CCV00719.1 - 0.87 9.4 9.1 9.3 6.1 0.1 4.2 4 1 0 4 4 3 0 ATPase domain predominantly from Archaea HBB PF06777.11 CCV00720.1 - 1.8e-46 158.2 2.3 3.2e-43 147.6 0.6 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 CCV00720.1 - 2.1e-44 151.7 0.0 4.2e-44 150.7 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CCV00720.1 - 8.1e-08 32.1 0.5 2.6e-07 30.4 0.3 1.9 2 0 0 2 2 2 1 DEAD_2 YtxC PF08812.11 CCV00720.1 - 0.39 10.3 2.3 0.45 10.1 0.0 2.2 3 0 0 3 3 3 0 YtxC-like family SNF2_N PF00176.23 CCV00721.1 - 3.6e-63 213.4 0.1 5e-63 212.9 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCV00721.1 - 2.1e-18 66.7 0.0 1.2e-16 61.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCV00721.1 - 1.3e-05 25.3 0.0 2.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CCV00721.1 - 0.0035 16.6 0.0 0.025 13.8 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CCV00721.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CCV00721.1 - 0.14 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Sec2p PF06428.11 CCV00722.1 - 1.6e-19 69.7 9.9 1.6e-19 69.7 9.9 2.7 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p SlyX PF04102.12 CCV00722.1 - 6.8 7.4 14.6 0.7 10.6 3.5 4.0 1 1 3 4 4 4 0 SlyX Pterin_bind PF00809.22 CCV00725.1 - 3.6e-65 220.0 0.0 6.4e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 CCV00725.1 - 3.6e-42 143.4 0.2 2.7e-23 82.6 0.2 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 CCV00725.1 - 5.4e-37 126.7 0.0 1.1e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Serinc PF03348.15 CCV00726.1 - 3.4e-131 438.1 4.2 4.2e-131 437.8 4.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF2207 PF09972.9 CCV00726.1 - 0.19 10.5 2.2 0.31 9.8 2.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2569 PF10754.9 CCV00726.1 - 2.7 8.4 14.9 0.032 14.7 2.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2569) GTP1_OBG PF01018.22 CCV00727.1 - 2.1e-37 128.1 2.5 1e-27 96.6 3.3 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 CCV00727.1 - 1.7e-20 73.2 0.0 3e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCV00727.1 - 1.7e-08 34.2 0.0 5e-07 29.4 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CCV00727.1 - 6.8e-05 22.5 0.0 0.0029 17.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CCV00727.1 - 0.0052 16.2 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family MeaB PF03308.16 CCV00727.1 - 0.012 14.6 0.0 1.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CCV00727.1 - 0.031 14.8 0.0 0.45 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CCV00727.1 - 0.048 14.2 0.0 0.096 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Phage_tail_APC PF16778.5 CCV00727.1 - 0.051 13.5 0.1 0.33 10.8 0.1 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Dynamin_N PF00350.23 CCV00727.1 - 0.14 12.2 0.0 12 5.9 0.0 2.3 1 1 1 2 2 2 0 Dynamin family Fe-S_biosyn PF01521.20 CCV00728.1 - 1.8e-18 66.7 0.0 2.3e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis tRNA-synt_2c PF01411.19 CCV00729.1 - 1.6e-213 710.2 0.0 2.1e-213 709.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CCV00729.1 - 1.1e-15 57.5 0.1 2.3e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CCV00729.1 - 1.5e-10 41.7 2.0 3.1e-10 40.6 2.0 1.6 1 0 0 1 1 1 1 DHHA1 domain zf-C2H2 PF00096.26 CCV00730.1 - 3.7e-12 46.0 17.7 3.4e-05 24.1 0.9 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCV00730.1 - 3.4e-08 33.7 14.8 0.015 16.1 0.1 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCV00730.1 - 4.6e-08 32.9 1.8 0.00066 19.6 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCV00730.1 - 8.7e-05 22.8 21.7 0.0056 17.1 0.1 4.7 6 0 0 6 6 6 2 Zinc-finger double domain zf-met PF12874.7 CCV00730.1 - 0.0001 22.6 0.7 0.047 14.1 0.2 3.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 CCV00730.1 - 0.0062 17.1 4.7 0.22 12.2 2.8 2.9 2 1 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CCV00730.1 - 0.0082 16.4 0.1 2 8.8 0.1 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CCV00730.1 - 0.68 9.9 7.5 7.2 6.6 0.1 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-TRAF PF02176.18 CCV00730.1 - 1.4 9.7 5.7 0.5 11.1 0.9 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger Zn-ribbon_8 PF09723.10 CCV00730.1 - 2.5 8.3 4.8 10 6.3 0.2 2.9 2 1 2 4 4 4 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 CCV00730.1 - 2.9 8.2 11.1 0.4 11.0 3.4 3.2 3 1 1 4 4 4 0 C2H2-type zinc ribbon adh_short PF00106.25 CCV00731.1 - 4.1e-17 62.3 1.1 2.1e-16 60.0 1.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCV00731.1 - 1.2e-09 38.0 1.8 3.8e-09 36.4 1.8 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CCV00731.1 - 4.6e-08 33.2 0.0 6.8e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CCV00731.1 - 7.1e-07 29.3 1.9 5.3e-06 26.4 1.9 2.0 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CCV00731.1 - 6.5e-06 26.1 0.1 1.1e-05 25.5 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CCV00731.1 - 0.098 13.2 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Helicase_RecD PF05127.14 CCV00731.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Helicase Asp PF00026.23 CCV00732.1 - 9.8e-45 153.3 2.2 3.1e-44 151.7 2.2 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 CCV00732.1 - 1.8e-05 25.3 0.1 0.088 13.5 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.6 CCV00732.1 - 0.00018 21.8 0.5 0.2 11.9 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 CCV00732.1 - 0.00031 21.2 0.0 0.63 10.6 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 CCV00732.1 - 0.086 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF3511 PF12023.8 CCV00734.1 - 0.088 12.6 3.3 1.4 8.8 1.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3511) Mitofilin PF09731.9 CCV00735.1 - 6.3e-99 332.5 37.9 1.9e-97 327.6 37.9 2.0 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Apolipoprotein PF01442.18 CCV00735.1 - 4.3e-05 23.5 9.0 4.3e-05 23.5 9.0 3.2 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain PDE4_UCR PF18100.1 CCV00735.1 - 1 10.0 7.4 0.21 12.2 1.1 2.8 3 0 0 3 3 3 0 Phosphodiesterase 4 upstream conserved regions (UCR) Flagellin_N PF00669.20 CCV00735.1 - 2.4 8.3 17.6 1.2 9.3 0.2 4.5 4 2 0 4 4 4 0 Bacterial flagellin N-terminal helical region DHBP_synthase PF00926.19 CCV00736.1 - 3.6e-80 268.0 0.1 4e-80 267.9 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase ATP-synt_ab PF00006.25 CCV00737.1 - 2.6e-106 354.1 0.0 3.5e-106 353.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CCV00737.1 - 2.4e-46 156.5 0.0 4.7e-46 155.6 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CCV00737.1 - 6.4e-13 49.0 1.8 1.7e-12 47.7 1.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Biotin_lipoyl PF00364.22 CCV00737.1 - 0.021 14.6 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Biotin-requiring enzyme AAA PF00004.29 CCV00738.1 - 2e-40 138.3 0.0 3.8e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCV00738.1 - 2.3e-06 27.3 0.0 5.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CCV00738.1 - 5.4e-05 23.5 0.0 0.005 17.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 CCV00738.1 - 8.4e-05 22.6 0.1 0.00034 20.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCV00738.1 - 0.00043 20.7 0.1 0.025 15.0 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CCV00738.1 - 0.00048 19.4 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 CCV00738.1 - 0.00053 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCV00738.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CCV00738.1 - 0.016 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CCV00738.1 - 0.017 14.7 0.0 0.038 13.5 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CCV00738.1 - 0.018 15.2 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCV00738.1 - 0.052 14.1 0.0 0.15 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 CCV00738.1 - 0.054 13.4 0.0 5.8 6.8 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 CCV00738.1 - 0.056 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CCV00738.1 - 0.057 12.8 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CCV00738.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4164 PF13747.6 CCV00738.1 - 0.061 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) IstB_IS21 PF01695.17 CCV00738.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 CCV00738.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 CCV00738.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 CCV00738.1 - 0.16 11.7 0.1 0.7 9.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain DUF4187 PF13821.6 CCV00739.1 - 1.9e-19 69.2 0.4 3.7e-19 68.2 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 CCV00739.1 - 0.0003 20.6 0.2 0.00083 19.2 0.0 1.8 2 0 0 2 2 2 1 G-patch domain PRP1_N PF06424.12 CCV00739.1 - 6.1 7.2 13.0 2 8.8 5.6 2.5 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal Thiolase_N PF00108.23 CCV00740.1 - 3.1e-90 302.1 2.1 3.1e-90 302.1 2.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CCV00740.1 - 4.5e-39 132.9 1.5 4.5e-39 132.9 1.5 2.2 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CCV00740.1 - 1.1e-05 25.2 0.8 1.1e-05 25.2 0.8 3.1 3 1 1 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CCV00740.1 - 0.0034 17.2 6.3 0.0077 16.1 0.1 3.1 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 CCV00741.1 - 1.3e-19 70.3 0.0 1.5e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CCV00741.1 - 0.028 14.7 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain KH_6 PF15985.5 CCV00742.1 - 3.7e-11 43.2 0.2 6.5e-11 42.4 0.2 1.4 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 CCV00742.1 - 1.7e-08 34.1 0.0 2.9e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 CCV00742.1 - 8.2e-05 23.2 0.1 0.02 15.5 0.0 2.5 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 MA3 PF02847.17 CCV00743.1 - 7e-30 103.3 0.3 1.4e-29 102.4 0.3 1.5 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 CCV00743.1 - 3.6e-14 52.9 0.1 5.8e-13 49.0 0.0 2.4 2 0 0 2 2 2 1 MIF4G domain Actin PF00022.19 CCV00745.1 - 4.2e-37 127.7 0.0 2e-24 86.0 0.0 2.3 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 CCV00745.1 - 0.027 13.3 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Ald_Xan_dh_C2 PF02738.18 CCV00745.1 - 0.083 11.3 0.0 0.13 10.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase SYF2 PF08231.12 CCV00746.1 - 1.5e-46 158.7 12.8 1.5e-46 158.7 12.8 1.7 2 0 0 2 2 2 1 SYF2 splicing factor Nipped-B_C PF12830.7 CCV00748.1 - 0.04 13.8 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus HTH_IclR PF09339.10 CCV00748.1 - 0.046 13.5 0.1 0.77 9.6 0.0 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain Abhydrolase_3 PF07859.13 CCV00749.1 - 2.4e-42 145.2 0.0 1.1e-32 113.6 0.0 2.9 2 1 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CCV00749.1 - 5.8e-08 32.0 0.0 2.5e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase AXE1 PF05448.12 CCV00749.1 - 0.016 13.9 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) COesterase PF00135.28 CCV00749.1 - 0.075 11.9 0.1 0.78 8.5 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family FAD_binding_6 PF00970.24 CCV00750.1 - 9.2e-27 93.3 0.0 1.4e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CCV00750.1 - 1.8e-26 92.9 0.0 8.4e-26 90.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CCV00750.1 - 0.0001 22.4 0.0 0.003 17.7 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain ATP_synt_H PF05493.13 CCV00750.1 - 0.03 14.8 1.0 0.066 13.7 0.1 1.9 2 0 0 2 2 2 0 ATP synthase subunit H DUF2207 PF09972.9 CCV00750.1 - 0.18 10.5 0.9 0.26 10.0 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AlaDh_PNT_N PF05222.15 CCV00751.1 - 8.1e-28 97.4 0.0 1.4e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 CCV00751.1 - 0.0072 15.6 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Mog1 PF04603.12 CCV00752.1 - 6.7e-35 120.4 0.0 7.9e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Ran-interacting Mog1 protein WD40 PF00400.32 CCV00753.1 - 1.7e-11 44.4 3.6 0.01 16.7 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCV00753.1 - 4.3e-08 33.4 0.0 0.00027 21.2 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CCV00753.1 - 0.0015 18.1 0.6 0.0041 16.7 0.4 1.9 1 1 0 1 1 1 1 PQQ-like domain eIF2A PF08662.11 CCV00753.1 - 0.07 13.0 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CCV00753.1 - 0.12 11.0 0.1 1.4 7.5 0.0 2.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Asn_synthase PF00733.21 CCV00754.1 - 4.2e-92 309.5 4.0 1.2e-55 189.7 0.2 3.0 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CCV00754.1 - 1.9e-37 127.9 0.0 3.2e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CCV00754.1 - 6.4e-32 110.6 0.0 2.7e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CCV00754.1 - 4.5e-05 23.0 0.0 8.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 CCV00754.1 - 0.003 16.7 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD synthase Pam16 PF03656.13 CCV00755.1 - 3.2e-15 56.3 0.2 6.6e-15 55.3 0.2 1.5 1 1 0 1 1 1 1 Pam16 IATP PF04568.12 CCV00755.1 - 1.4 9.4 4.6 3.8 8.0 0.2 2.2 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Mitofilin PF09731.9 CCV00756.1 - 0.023 13.6 16.1 0.03 13.2 16.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Borrelia_P83 PF05262.11 CCV00756.1 - 0.61 8.5 8.0 0.64 8.4 8.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FYVE PF01363.21 CCV00758.1 - 4.5 7.5 7.4 11 6.2 7.5 1.6 1 1 0 1 1 1 0 FYVE zinc finger Ras PF00071.22 CCV00759.1 - 3.6e-33 114.5 0.0 4.1e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCV00759.1 - 1.2e-08 35.2 0.0 1.8e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CCV00759.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PET117 PF15786.5 CCV00759.1 - 0.17 12.1 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial tRNA_Me_trans PF03054.16 CCV00761.1 - 2.4e-91 306.2 0.0 2.7e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase CENP-C_C PF11699.8 CCV00762.1 - 3.9e-10 39.8 0.0 0.00017 21.7 0.0 2.2 2 0 0 2 2 2 2 Mif2/CENP-C like AT_hook PF02178.19 CCV00762.1 - 0.024 14.4 2.8 0.024 14.4 2.8 4.1 3 0 0 3 3 3 0 AT hook motif Xin PF08043.12 CCV00764.1 - 0.17 11.5 0.5 0.51 10.1 0.5 1.9 1 0 0 1 1 1 0 Xin repeat FAD_binding_7 PF03441.14 CCV00765.1 - 2.1e-78 262.4 3.4 4.9e-78 261.3 3.2 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CCV00765.1 - 4.4e-32 111.4 0.0 1.4e-31 109.8 0.0 1.8 2 0 0 2 2 2 1 DNA photolyase 2OG-FeII_Oxy PF03171.20 CCV00766.1 - 2.9e-18 66.2 0.0 4.9e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CCV00766.1 - 2.7e-10 41.0 0.0 9.8e-06 26.3 0.0 2.4 1 1 1 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal EABR PF12180.8 CCV00766.1 - 0.049 13.2 0.2 0.1 12.2 0.2 1.5 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 MFS_1 PF07690.16 CCV00767.1 - 2.1e-29 102.6 67.9 1.6e-27 96.3 42.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily GMC_oxred_N PF00732.19 CCV00768.1 - 6.5e-49 166.9 0.0 8.8e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CCV00768.1 - 4.8e-26 92.0 0.0 1e-25 90.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CCV00768.1 - 9.8e-06 24.9 0.1 0.0055 15.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CCV00768.1 - 0.00013 22.2 0.0 0.00038 20.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CCV00768.1 - 0.00061 19.5 1.3 0.017 14.8 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CCV00768.1 - 0.0041 16.2 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CCV00768.1 - 0.0051 16.1 0.1 0.024 13.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCV00768.1 - 0.0097 15.2 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Endotoxin_mid PF09131.10 CCV00768.1 - 0.021 14.5 0.1 0.035 13.8 0.1 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis delta-Endotoxin, middle domain HI0933_like PF03486.14 CCV00768.1 - 0.073 11.8 0.0 0.35 9.5 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_43 PF04616.14 CCV00769.1 - 4.2e-39 134.6 0.0 3.8e-37 128.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 ADH_zinc_N PF00107.26 CCV00769.1 - 2.9e-25 88.8 0.0 6.2e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCV00769.1 - 4.2e-11 44.0 0.1 1.1e-10 42.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCV00769.1 - 8.4e-11 41.7 0.0 3.5e-10 39.7 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AA_kinase PF00696.28 CCV00770.1 - 7.3e-35 120.7 0.0 1.7e-34 119.5 0.0 1.6 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 CCV00770.1 - 1.7e-09 37.2 0.3 0.0014 18.4 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 CCV00770.1 - 7.3e-09 35.3 1.4 1.1e-05 25.1 0.2 2.6 2 0 0 2 2 2 2 ACT domain Cse1 PF08506.10 CCV00771.1 - 2.6e-126 421.4 0.0 4.2e-126 420.7 0.0 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 CCV00771.1 - 1.4e-122 409.4 0.0 2.2e-122 408.7 0.0 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 CCV00771.1 - 2.2e-16 59.5 1.3 8.5e-14 51.2 0.2 3.4 2 0 0 2 2 2 2 Importin-beta N-terminal domain Xpo1 PF08389.12 CCV00771.1 - 0.00096 19.2 5.5 0.0055 16.8 0.3 4.5 5 2 2 7 7 7 1 Exportin 1-like protein Phyto_Pns9_10 PF05878.11 CCV00771.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 RNB PF00773.19 CCV00772.1 - 1.3e-31 110.2 0.0 2.8e-21 76.2 0.0 2.3 2 0 0 2 2 2 2 RNB domain OB_Dis3 PF17849.1 CCV00772.1 - 2.1e-20 72.5 0.0 4.8e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CCV00772.1 - 1.8e-13 50.6 0.0 4.3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 CCV00772.1 - 0.00015 21.5 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Rrp44-like cold shock domain FlxA PF14282.6 CCV00772.1 - 0.054 13.5 14.6 0.098 12.7 10.5 2.8 2 0 0 2 2 2 0 FlxA-like protein Metal_CEHH PF14455.6 CCV00772.1 - 0.091 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Predicted metal binding domain NIF PF03031.18 CCV00773.1 - 2.6e-08 33.8 0.0 0.0093 15.7 0.0 2.6 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase ACOX PF01756.19 CCV00774.1 - 9.6e-43 145.8 0.0 1.6e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 CCV00774.1 - 5.8e-20 71.3 0.2 1e-19 70.5 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CCV00774.1 - 1.1e-06 28.9 0.0 3.5e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 CCV00774.1 - 4.7e-06 27.2 0.0 1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Mito_carr PF00153.27 CCV00775.1 - 1.3e-62 207.7 5.3 6.3e-22 77.3 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 CCV00775.1 - 0.00017 20.9 0.5 0.0018 17.7 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 CCV00775.1 - 0.00023 20.8 0.0 0.0023 17.7 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CCV00775.1 - 0.00027 21.3 0.1 0.00082 19.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CCV00775.1 - 0.0056 16.5 0.3 0.022 14.6 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair V-ATPase_H_N PF03224.14 CCV00775.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 V-ATPase subunit H SPARC_Ca_bdg PF10591.9 CCV00775.1 - 0.52 10.6 2.1 3.6 7.9 0.1 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Tubulin PF00091.25 CCV00776.1 - 4.5e-67 226.1 0.0 6.1e-67 225.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CCV00776.1 - 1.3e-48 164.3 0.0 2e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CCV00776.1 - 0.0005 19.8 0.0 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CCV00776.1 - 0.094 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin like SRF-TF PF00319.18 CCV00777.1 - 1.3e-19 69.4 0.0 2.5e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) zf-U1 PF06220.12 CCV00777.1 - 3.1e-07 30.0 1.3 5.9e-07 29.1 1.3 1.5 1 0 0 1 1 1 1 U1 zinc finger Ribosomal_60s PF00428.19 CCV00777.1 - 0.036 14.6 2.4 0.036 14.6 2.4 5.1 3 1 2 5 5 5 0 60s Acidic ribosomal protein CPSF_A PF03178.15 CCV00778.1 - 1.7e-56 191.9 0.0 3e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region Ribosomal_S26e PF01283.19 CCV00779.1 - 1.1e-53 180.2 6.6 1.3e-53 180.0 6.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e HC2 PF07382.11 CCV00780.1 - 0.01 16.0 1.4 0.01 16.0 1.4 2.6 2 1 0 3 3 3 0 Histone H1-like nucleoprotein HC2 Glyco_hydro_16 PF00722.21 CCV00781.1 - 2.3e-21 76.1 0.0 4e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKG6 PF08693.10 CCV00781.1 - 0.0087 15.4 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Chitin_bind_1 PF00187.19 CCV00781.1 - 0.042 14.3 11.9 0.087 13.3 11.9 1.5 1 0 0 1 1 1 0 Chitin recognition protein DUF2062 PF09835.9 CCV00781.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF5320 PF17253.2 CCV00782.1 - 0.0074 17.3 0.1 0.013 16.6 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5320) bZIP_1 PF00170.21 CCV00782.1 - 0.09 12.9 6.1 0.23 11.6 0.2 2.4 2 0 0 2 2 2 0 bZIP transcription factor DDHD PF02862.17 CCV00783.1 - 7.7e-15 55.7 0.0 3e-13 50.5 0.0 2.3 1 1 1 2 2 2 2 DDHD domain 5_nucleotid_C PF02872.18 CCV00785.1 - 0.022 15.0 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain DUF676 PF05057.14 CCV00786.1 - 0.0004 20.0 0.0 0.00091 18.8 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CCV00786.1 - 0.0086 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 CCV00786.1 - 0.18 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase UCH PF00443.29 CCV00788.1 - 7.5e-37 127.2 0.0 1.2e-36 126.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 CCV00788.1 - 5e-12 45.6 0.0 5.1e-10 39.1 0.1 2.6 2 0 0 2 2 2 1 A repeated domain in UCH-protein UCH_1 PF13423.6 CCV00788.1 - 2.3e-08 34.0 0.0 0.0066 16.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase FlgN PF05130.12 CCV00788.1 - 0.059 13.9 0.6 0.18 12.3 0.6 1.9 1 0 0 1 1 1 0 FlgN protein Cas3_C PF18395.1 CCV00788.1 - 0.093 13.2 0.4 0.42 11.1 0.4 2.2 1 0 0 1 1 1 0 Cas3 C-terminal domain Rer1 PF03248.13 CCV00789.1 - 5.3e-76 254.1 0.7 6.4e-76 253.9 0.7 1.1 1 0 0 1 1 1 1 Rer1 family Cupin_8 PF13621.6 CCV00790.1 - 9.3e-44 150.0 0.0 1.2e-43 149.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CCV00790.1 - 0.033 13.6 0.5 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Cupin superfamily protein RNA_pol_3_Rpc31 PF11705.8 CCV00790.1 - 0.066 13.5 5.5 0.12 12.6 4.6 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 CCV00790.1 - 0.57 8.3 3.3 0.71 8.0 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 CCV00790.1 - 1.6 8.8 3.3 2.7 8.0 3.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal LIP PF03583.14 CCV00791.1 - 6.6e-62 209.4 0.0 9.3e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_2 PF02230.16 CCV00791.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 CCV00791.1 - 0.099 12.1 4.2 4 6.8 0.0 2.9 2 1 1 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CCV00791.1 - 0.15 12.7 2.8 1.3 9.5 2.9 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family LIP PF03583.14 CCV00792.1 - 1e-59 202.3 0.0 1.3e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase DLH PF01738.18 CCV00792.1 - 0.053 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Cu_amine_oxid PF01179.20 CCV00793.1 - 1.4e-160 534.8 0.0 1.6e-160 534.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 CCV00793.1 - 4.4e-07 30.2 0.0 1.9e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain PAP_assoc PF03828.19 CCV00797.1 - 1.5e-14 54.0 0.0 2.7e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CCV00797.1 - 7.3e-07 29.4 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CCV00797.1 - 0.00045 20.2 0.0 0.00073 19.6 0.0 1.3 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase TFIID_30kDa PF03540.13 CCV00798.1 - 1.4e-09 37.7 0.0 2.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.28 CCV00798.1 - 1.6e-05 25.2 0.0 0.00083 19.8 0.0 2.5 3 0 0 3 3 3 1 CBS domain Peptidase_M13_N PF05649.13 CCV00800.1 - 1.8e-78 264.9 0.0 2.6e-78 264.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CCV00800.1 - 1.8e-57 194.3 0.0 9.2e-57 192.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M13 Orexin PF02072.15 CCV00800.1 - 0.054 13.4 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 Prepro-orexin Helicase_C PF00271.31 CCV00801.1 - 3.4e-14 53.1 0.0 6.6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CCV00801.1 - 1.3e-11 44.7 0.0 2.4e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CCV00801.1 - 2.7e-10 40.5 1.6 3e-10 40.3 0.1 1.9 2 0 0 2 2 1 1 Helicase associated domain (HA2) DEAD PF00270.29 CCV00801.1 - 4.3e-10 39.6 0.0 6.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 CCV00801.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 CCV00801.1 - 0.0026 18.0 0.0 0.0083 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CCV00801.1 - 0.024 14.6 0.1 0.056 13.4 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_16 PF13191.6 CCV00801.1 - 0.03 14.7 0.4 0.03 14.7 0.4 3.1 5 0 0 5 5 4 0 AAA ATPase domain T2SSE PF00437.20 CCV00801.1 - 0.036 13.1 0.0 0.084 11.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 CCV00801.1 - 0.054 13.5 0.0 0.29 11.1 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CCV00801.1 - 0.073 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CCV00801.1 - 0.089 12.7 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 CCV00801.1 - 0.14 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Pan3_PK PF18101.1 CCV00802.1 - 6.9e-57 191.3 0.0 9.8e-57 190.8 0.0 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain RINGv PF12906.7 CCV00807.1 - 5.3e-13 48.9 5.2 8.8e-13 48.2 5.2 1.3 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 CCV00807.1 - 0.49 10.6 2.1 0.79 9.9 2.1 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 CCV00807.1 - 0.62 10.4 3.7 1.1 9.7 3.7 1.4 1 0 0 1 1 1 0 Ring finger domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Malassezia_sympodialis_ATCC_42132-ASM34930v2/GCA_000349305.2_ASM34930v2_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Malassezia_sympodialis_ATCC_42132-ASM34930v2/GCA_000349305.2_ASM34930v2_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Malassezia_sympodialis_ATCC_42132-ASM34930v2/GCA_000349305.2_ASM34930v2_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Malassezia_sympodialis_ATCC_42132-ASM34930v2/GCA_000349305.2_ASM34930v2_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 22:26:51 2019 # [ok]