# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- MFS_1 PF07690.11 CCU97295.1 - 4.7e-19 68.3 34.7 2.5e-18 65.9 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 CCU97296.1 - 9.9e-11 41.1 11.8 0.03 14.2 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat PACT_coil_coil PF10495.4 CCU97297.1 - 0.00033 20.5 0.3 0.0012 18.7 0.2 2.0 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF3584 PF12128.3 CCU97297.1 - 0.1 9.8 50.1 0.083 10.2 1.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) HALZ PF02183.13 CCU97297.1 - 0.41 10.4 17.5 3.1 7.5 0.2 5.5 6 0 0 6 6 6 0 Homeobox associated leucine zipper Phage_GP20 PF06810.6 CCU97297.1 - 3.7 6.9 17.5 0.087 12.2 5.3 3.1 2 1 1 3 3 3 0 Phage minor structural protein GP20 ADIP PF11559.3 CCU97298.1 - 0.0055 16.6 2.1 0.0055 16.6 1.5 3.1 2 1 1 3 3 3 2 Afadin- and alpha -actinin-Binding RNase_HII PF01351.13 CCU97298.1 - 0.94 9.0 4.7 1.4 8.5 3.3 1.3 1 0 0 1 1 1 0 Ribonuclease HII Sugar_tr PF00083.19 CCU97300.1 - 1.9e-16 59.7 24.3 8.7e-16 57.5 16.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter WD40 PF00400.27 CCU97301.1 - 7.8e-45 149.2 13.3 1.8e-08 33.9 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 CCU97301.1 - 0.00041 18.6 1.0 0.22 9.6 0.2 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 CCU97301.1 - 0.0019 17.3 1.1 1.1 8.3 0.0 3.0 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal HARP PF07443.8 CCU97301.1 - 4.3 6.7 4.8 12 5.3 0.0 3.1 4 0 0 4 4 4 0 HepA-related protein (HARP) CHCH PF06747.8 CCU97302.1 - 1.9e-07 30.8 3.6 3.2e-07 30.0 2.5 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 CCU97302.1 - 0.013 15.6 1.7 0.022 14.8 1.2 1.4 1 0 0 1 1 1 0 GCK domain DUF2320 PF10082.4 CCU97303.1 - 0.067 11.9 14.9 0.097 11.3 10.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2320) DUF2807 PF10988.3 CCU97303.1 - 8.4 5.8 6.2 62 3.0 4.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2807) Ytp1 PF10355.4 CCU97304.1 - 5.2e-76 255.4 17.0 5.2e-76 255.4 11.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CCU97304.1 - 7.9e-21 73.6 2.3 7.9e-21 73.6 1.6 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) SAM_2 PF07647.12 CCU97305.1 - 1.5e-15 56.7 0.0 2.8e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CCU97305.1 - 1.6e-14 53.8 0.0 2.7e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 CCU97305.1 - 2.1e-07 30.2 0.1 8.9e-07 28.2 0.1 2.2 1 0 0 1 1 1 1 SH3 domain RA PF00788.18 CCU97305.1 - 3.2e-06 27.5 0.0 5.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_9 PF14604.1 CCU97305.1 - 0.00011 21.6 0.1 0.00037 20.0 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SAM_PNT PF02198.11 CCU97305.1 - 0.015 14.9 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Sec7 PF01369.15 CCU97306.1 - 8.3e-14 51.6 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain SAGA-Tad1 PF12767.2 CCU97306.1 - 9 5.8 5.8 21 4.6 0.3 2.7 2 1 1 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit Cullin PF00888.17 CCU97307.1 - 4.5e-30 104.7 0.0 5.4e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Cullin family RmlD_sub_bind PF04321.12 CCU97308.1 - 1.4e-53 181.6 0.1 2.9e-53 180.6 0.1 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain Vps5 PF09325.5 CCU97308.1 - 2.6e-41 141.4 6.6 3.9e-41 140.8 4.6 1.2 1 0 0 1 1 1 1 Vps5 C terminal like Epimerase PF01370.16 CCU97308.1 - 1.7e-28 99.6 0.0 3.5e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PX PF00787.19 CCU97308.1 - 2.7e-22 78.7 0.0 5.9e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 PX domain NAD_binding_10 PF13460.1 CCU97308.1 - 1.4e-13 51.2 0.8 2.6e-13 50.4 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCU97308.1 - 9.4e-13 47.6 0.2 1.1e-09 37.6 0.0 2.4 1 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 CCU97308.1 - 2.2e-11 43.2 0.2 5.9e-09 35.2 0.0 2.6 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CCU97308.1 - 2.5e-07 29.6 0.0 9.3e-07 27.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CCU97308.1 - 0.0025 17.0 0.0 0.005 16.1 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CCU97308.1 - 0.0056 16.6 9.5 0.14 12.0 4.7 3.5 2 1 0 2 2 2 1 short chain dehydrogenase Arfaptin PF06456.8 CCU97308.1 - 0.032 13.5 0.2 0.032 13.5 0.1 1.7 2 0 0 2 2 2 0 Arfaptin-like domain DapB_N PF01113.15 CCU97308.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus STAS_2 PF13466.1 CCU97308.1 - 0.43 10.6 10.5 2.2 8.3 1.7 4.1 3 0 0 3 3 3 0 STAS domain 60KD_IMP PF02096.15 CCU97310.1 - 1.5e-41 142.2 2.3 2.1e-41 141.7 1.6 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF1569 PF07606.6 CCU97310.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) DUF1211 PF06736.6 CCU97310.1 - 0.09 12.9 0.3 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) TBP PF00352.16 CCU97311.1 - 8.6e-67 220.5 0.2 1.1e-32 111.2 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CCU97311.1 - 7e-05 22.8 0.0 0.39 10.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) HSF_DNA-bind PF00447.12 CCU97312.1 - 6.4e-23 80.9 0.6 1.7e-22 79.5 0.4 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Orthopox_A5L PF06193.6 CCU97312.1 - 0.026 14.4 2.2 2.6 7.9 0.1 2.4 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like DUF948 PF06103.6 CCU97312.1 - 0.051 13.4 2.9 0.62 9.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cortex-I_coil PF09304.5 CCU97312.1 - 0.39 10.7 6.7 0.2 11.7 1.2 2.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil RNA_pol_Rpc82 PF05645.8 CCU97313.1 - 7.8e-06 25.6 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 Death PF00531.17 CCU97313.1 - 0.016 14.9 1.1 0.069 12.9 0.7 2.0 1 1 1 2 2 2 0 Death domain Cyto_heme_lyase PF01265.12 CCU97315.1 - 1.5e-65 221.3 6.4 3.2e-65 220.2 4.4 1.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Sld5 PF05916.6 CCU97316.1 - 0.00023 21.4 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Gp49 PF05973.9 CCU97316.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Phage derived protein Gp49-like (DUF891) UPF0052 PF01933.13 CCU97317.1 - 0.079 12.2 0.1 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 tRNA_U5-meth_tr PF05958.6 CCU97318.1 - 4.2e-11 42.1 0.0 1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 CCU97318.1 - 6.2e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CCU97318.1 - 6.1e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRAM PF01938.15 CCU97318.1 - 2e-05 24.2 0.0 4.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 TRAM domain Methyltransf_26 PF13659.1 CCU97318.1 - 3.4e-05 23.8 0.0 6.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCU97318.1 - 6e-05 23.5 0.0 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCU97318.1 - 6.2e-05 22.2 0.0 9.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CCU97318.1 - 0.00019 20.8 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 CCU97318.1 - 0.0012 19.2 0.0 0.0027 18.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CCU97318.1 - 0.0047 16.0 0.1 0.014 14.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_32 PF13679.1 CCU97318.1 - 0.0091 15.6 0.2 0.026 14.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain TRM PF02005.11 CCU97318.1 - 0.015 14.2 0.0 0.029 13.2 0.0 1.5 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase TPMT PF05724.6 CCU97318.1 - 0.016 14.6 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Met_10 PF02475.11 CCU97318.1 - 0.025 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.7 CCU97318.1 - 0.029 14.8 0.0 0.07 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RhoGAP PF00620.22 CCU97319.1 - 5.4e-36 123.4 0.0 1.2e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Apolipoprotein PF01442.13 CCU97319.1 - 0.026 14.0 4.8 0.055 12.9 3.3 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4455 PF14643.1 CCU97319.1 - 0.032 12.8 1.8 0.05 12.2 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Filament PF00038.16 CCU97319.1 - 0.069 12.6 4.1 0.11 11.9 2.8 1.2 1 0 0 1 1 1 0 Intermediate filament protein TMF_TATA_bd PF12325.3 CCU97319.1 - 0.65 9.7 8.7 6.7 6.4 3.5 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding KH_1 PF00013.24 CCU97320.1 - 1.1e-27 95.4 0.1 9.6e-10 37.9 0.0 5.9 6 0 0 6 6 6 4 KH domain KH_3 PF13014.1 CCU97320.1 - 1.5e-23 81.9 0.6 1.3e-07 31.0 0.1 6.0 6 0 0 6 6 6 4 KH domain ComA PF02679.10 CCU97320.1 - 0.017 14.1 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) BMC PF00936.14 CCU97320.1 - 0.019 14.6 0.2 2.3 7.9 0.0 3.3 3 0 0 3 3 3 0 BMC domain RNA_pol_Rpb5_N PF03871.9 CCU97321.1 - 5.1e-29 100.5 0.7 6.6e-29 100.1 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 CCU97321.1 - 0.00072 19.3 0.1 0.0011 18.7 0.0 1.5 1 1 0 1 1 1 1 Restriction endonuclease PqqD PF05402.7 CCU97321.1 - 0.057 13.4 0.0 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) NAD_binding_1 PF00175.16 CCU97322.1 - 8e-26 90.7 0.0 1.3e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CCU97322.1 - 2.3e-18 66.1 0.0 4.1e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CCU97322.1 - 4.6e-06 26.6 0.0 0.0047 16.8 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CCU97322.1 - 2.9e-05 24.0 0.0 0.00017 21.5 0.0 2.0 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain ABC_ATPase PF09818.4 CCU97323.1 - 2.6e-132 441.5 0.0 2.3e-116 389.0 0.0 3.1 1 1 2 3 3 3 3 Predicted ATPase of the ABC class AAA_25 PF13481.1 CCU97323.1 - 0.0002 20.8 0.0 0.00052 19.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain Chitin_synth_2 PF03142.10 CCU97324.1 - 6.6e-226 750.7 0.0 9.3e-226 750.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CCU97324.1 - 2.2e-15 56.8 3.4 2.2e-15 56.8 2.4 2.8 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCU97324.1 - 6.7e-15 55.4 0.1 1.5e-13 51.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 CCU97324.1 - 1.3e-06 28.1 0.0 0.0011 18.6 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 CCU97324.1 - 0.00061 19.1 0.2 0.34 10.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 DUF1049 PF06305.6 CCU97324.1 - 2.4 7.6 11.4 5.8 6.4 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Bromodomain PF00439.20 CCU97325.1 - 5.9e-11 42.1 0.0 1.3e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BAH PF01426.13 CCU97325.1 - 1.2e-10 41.1 0.0 2.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 BAH domain tRNA-synt_1b PF00579.20 CCU97327.1 - 2.9e-23 82.4 0.0 7.2e-23 81.1 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Vmethyltransf PF01660.12 CCU97327.1 - 0.054 12.1 0.0 0.075 11.6 0.0 1.2 1 0 0 1 1 1 0 Viral methyltransferase LSM PF01423.17 CCU97328.1 - 4e-12 45.5 0.0 5.6e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCU97328.1 - 8.3e-05 22.4 0.0 9.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Avl9 PF09794.4 CCU97329.1 - 7.1e-97 324.2 0.1 8.5e-97 323.9 0.1 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 CCU97329.1 - 1.6e-05 24.5 0.9 0.0053 16.4 0.0 2.7 2 1 1 3 3 3 2 Stabilization of polarity axis DUF2347 PF09804.4 CCU97329.1 - 0.00011 21.6 0.2 0.00029 20.2 0.2 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.16 CCU97329.1 - 0.051 13.2 1.4 6 6.5 0.0 3.0 2 1 0 2 2 2 0 DENN (AEX-3) domain Fibrillarin PF01269.12 CCU97330.1 - 3.1e-111 369.8 0.0 3.9e-111 369.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CCU97330.1 - 1.7e-05 24.4 0.0 2.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CCU97330.1 - 0.0071 15.8 0.1 0.011 15.3 0.0 1.3 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 CCU97330.1 - 0.013 15.1 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Tubulin PF00091.20 CCU97331.1 - 7.3e-73 244.9 0.0 1.5e-72 243.9 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCU97331.1 - 3.4e-45 153.1 0.5 4.9e-45 152.6 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CCU97331.1 - 1.7e-06 28.0 0.0 3.9e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain DUF4451 PF14616.1 CCU97331.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Ion_trans PF00520.26 CCU97332.1 - 2.9e-28 98.4 30.1 6.3e-18 64.7 12.5 2.3 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.7 CCU97332.1 - 0.18 10.2 23.1 0.78 8.0 3.1 2.8 2 1 0 2 2 2 0 Polycystin cation channel Ion_trans PF00520.26 CCU97333.1 - 5.2e-40 136.8 26.6 1e-21 77.1 1.7 2.3 2 0 0 2 2 2 2 Ion transport protein FlhC PF05280.6 CCU97333.1 - 0.03 13.7 0.4 1.8 7.9 0.0 3.2 3 1 0 3 3 3 0 Flagellar transcriptional activator (FlhC) BCS1_N PF08740.6 CCU97334.1 - 2.4e-49 167.5 0.0 3.4e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CCU97334.1 - 1.9e-08 34.5 0.0 3.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MgtE PF01769.11 CCU97335.1 - 1.1e-10 41.9 26.5 5.1e-06 26.8 0.2 4.8 4 1 1 5 5 5 3 Divalent cation transporter PCI PF01399.22 CCU97336.1 - 1.1e-09 38.5 0.1 1.1e-09 38.5 0.1 3.0 4 0 0 4 4 4 1 PCI domain DUF382 PF04037.8 CCU97337.1 - 7.3e-58 193.9 0.1 1.6e-57 192.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 CCU97337.1 - 3.1e-18 64.8 7.5 3.1e-18 64.8 5.2 2.3 2 0 0 2 2 2 1 PSP Nop14 PF04147.7 CCU97337.1 - 0.066 11.1 7.5 0.14 10.0 5.2 1.5 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 CCU97337.1 - 2.3 7.8 7.4 1.8 8.2 2.3 2.3 2 0 0 2 2 2 0 FAM176 family Nucleoplasmin PF03066.10 CCU97337.1 - 9.6 5.7 15.7 20 4.6 10.9 1.5 1 0 0 1 1 1 0 Nucleoplasmin Proteasome PF00227.21 CCU97338.1 - 4.8e-50 169.4 0.1 6e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CCU97338.1 - 1.2e-10 40.4 0.4 2.6e-10 39.3 0.2 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Rio2_N PF09202.6 CCU97338.1 - 0.083 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal Pyr_redox_2 PF07992.9 CCU97339.1 - 6.3e-22 78.4 0.0 1.7e-21 77.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 CCU97339.1 - 1.3e-14 53.5 0.0 2.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 CCU97339.1 - 5e-11 42.8 0.1 7.6e-08 32.6 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 CCU97339.1 - 4.4e-06 26.3 0.0 8.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.1 CCU97339.1 - 1.4e-05 25.3 0.0 0.00026 21.1 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 CCU97339.1 - 0.0025 18.0 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal FAD_binding_2 PF00890.19 CCU97339.1 - 0.0099 14.7 0.2 0.16 10.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 CCU97339.1 - 0.065 12.6 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain EF-hand_4 PF12763.2 CCU97340.1 - 2.9e-35 120.1 0.0 1e-13 50.8 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CCU97340.1 - 1.1e-09 38.2 0.1 0.00021 21.3 0.0 4.1 4 1 1 5 5 4 2 EF-hand domain pair UBA PF00627.26 CCU97340.1 - 9.2e-07 28.5 0.0 2.9e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain EF-hand_1 PF00036.27 CCU97340.1 - 2.2e-06 26.5 0.0 0.036 13.3 0.0 4.3 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 CCU97340.1 - 0.0002 20.9 2.0 2.1 8.4 0.0 5.5 6 0 0 6 6 6 1 EF-hand domain EF-hand_8 PF13833.1 CCU97340.1 - 0.001 18.5 0.0 0.8 9.3 0.0 3.8 5 0 0 5 5 5 1 EF-hand domain pair ERM PF00769.14 CCU97340.1 - 0.011 15.2 25.2 0.021 14.3 17.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ATG16 PF08614.6 CCU97340.1 - 0.019 14.7 29.3 0.056 13.2 20.3 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) UBA_3 PF09288.5 CCU97340.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain AAA_13 PF13166.1 CCU97340.1 - 0.19 10.1 16.3 0.27 9.6 11.3 1.1 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.4 CCU97340.1 - 0.33 9.1 12.4 0.48 8.6 8.6 1.2 1 0 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 CCU97340.1 - 0.36 8.6 11.6 0.52 8.1 8.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 CCU97340.1 - 0.38 9.8 8.4 0.17 11.0 2.9 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein RTBV_P46 PF06216.6 CCU97340.1 - 0.89 8.3 3.1 1.5 7.6 2.2 1.3 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DivIC PF04977.10 CCU97340.1 - 1.1 8.7 23.3 1 8.8 3.9 3.3 2 1 1 3 3 3 0 Septum formation initiator DUF4200 PF13863.1 CCU97340.1 - 3 7.7 25.1 5.3 7.0 17.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ADIP PF11559.3 CCU97340.1 - 3.9 7.3 31.2 2.4 8.0 10.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding EF-hand_5 PF13202.1 CCU97340.1 - 6.1 6.3 6.2 1.1 8.7 0.0 2.7 3 0 0 3 3 3 0 EF hand IncA PF04156.9 CCU97340.1 - 6.3 6.3 34.3 71 2.9 23.7 2.1 1 1 0 1 1 1 0 IncA protein SAGA-Tad1 PF12767.2 CCU97341.1 - 2.5e-36 125.6 0.2 4.6e-36 124.7 0.0 1.5 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit Pkinase PF00069.20 CCU97342.1 - 3e-60 203.5 0.0 4e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97342.1 - 5.2e-39 133.8 0.0 7.5e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU97342.1 - 1.6e-05 23.9 0.0 6e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCU97342.1 - 0.12 12.0 3.9 0.29 10.8 0.0 3.0 3 1 0 3 3 3 0 Phosphotransferase enzyme family SPRY PF00622.23 CCU97343.1 - 7.3e-16 58.3 0.1 1.2e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 SPRY domain bZIP_1 PF00170.16 CCU97344.1 - 1.3e-06 28.2 9.0 1.7e-06 27.9 3.3 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CCU97344.1 - 0.29 10.9 9.4 0.23 11.3 3.9 2.2 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.12 CCU97344.1 - 0.49 10.7 5.0 0.98 9.7 3.5 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor KTI12 PF08433.5 CCU97345.1 - 1.6e-10 40.6 0.5 4.7e-06 26.0 0.0 4.0 3 1 1 4 4 4 4 Chromatin associated protein KTI12 DUF2407_C PF13373.1 CCU97345.1 - 0.056 13.3 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain DEAD PF00270.24 CCU97347.1 - 2.2e-42 144.4 0.0 1.9e-41 141.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU97347.1 - 8.4e-24 83.2 0.0 4.3e-23 80.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Latrophilin PF02354.11 CCU97347.1 - 0.025 13.3 0.6 0.039 12.6 0.4 1.2 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region ResIII PF04851.10 CCU97347.1 - 0.032 14.0 0.0 4.2 7.1 0.0 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PAP_assoc PF03828.14 CCU97348.1 - 3.4e-13 49.3 0.0 7.4e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase AAA PF00004.24 CCU97349.1 - 3.9e-35 120.9 0.0 5.2e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCU97349.1 - 1.2e-09 38.4 0.2 2.4e-09 37.4 0.2 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCU97349.1 - 1.2e-08 35.1 0.1 3.4e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCU97349.1 - 9.6e-08 32.8 0.1 7.7e-07 29.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCU97349.1 - 7.7e-07 28.6 0.3 0.0044 16.4 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 CCU97349.1 - 2.1e-06 27.7 0.0 6.4e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CCU97349.1 - 4.4e-06 26.6 0.0 1.2e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCU97349.1 - 5.3e-06 26.2 0.1 1.4e-05 24.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CCU97349.1 - 7.2e-06 26.3 0.0 1e-05 25.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCU97349.1 - 1e-05 25.1 0.1 0.0001 21.9 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 CCU97349.1 - 5.8e-05 22.7 0.0 9.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 CCU97349.1 - 5.8e-05 22.7 0.0 9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCU97349.1 - 0.0001 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCU97349.1 - 0.00019 20.5 0.2 0.0019 17.2 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CCU97349.1 - 0.00021 20.9 0.4 0.0013 18.4 0.2 2.2 1 1 0 1 1 1 1 NACHT domain AAA_11 PF13086.1 CCU97349.1 - 0.0003 20.4 0.0 0.00047 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCU97349.1 - 0.00032 20.1 0.0 0.0015 17.9 0.0 2.1 3 0 0 3 3 2 1 IstB-like ATP binding protein UPF0079 PF02367.12 CCU97349.1 - 0.00033 20.2 0.0 0.00061 19.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CCU97349.1 - 0.00034 20.7 0.0 0.00088 19.4 0.0 1.7 1 1 1 2 2 1 1 RNA helicase Arch_ATPase PF01637.13 CCU97349.1 - 0.0011 18.7 0.4 1.4 8.5 0.0 2.1 1 1 1 2 2 2 2 Archaeal ATPase KAP_NTPase PF07693.9 CCU97349.1 - 0.0012 17.8 0.0 0.87 8.5 0.0 2.7 2 2 1 3 3 3 1 KAP family P-loop domain Zeta_toxin PF06414.7 CCU97349.1 - 0.0013 17.8 0.0 0.0025 16.9 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 CCU97349.1 - 0.0019 18.2 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 CCU97349.1 - 0.002 17.0 0.3 0.0097 14.8 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 CCU97349.1 - 0.0031 17.8 0.0 0.011 16.1 0.0 1.6 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 CCU97349.1 - 0.0054 17.0 0.0 0.0081 16.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter NTPase_1 PF03266.10 CCU97349.1 - 0.0079 15.9 0.1 0.028 14.1 0.1 1.8 1 1 1 2 2 2 1 NTPase AAA_30 PF13604.1 CCU97349.1 - 0.012 15.2 0.0 0.03 13.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.8 CCU97349.1 - 0.013 14.2 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 CCU97349.1 - 0.02 14.0 0.0 0.064 12.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 CCU97349.1 - 0.02 13.8 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 CCU97349.1 - 0.027 13.6 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 CCU97349.1 - 0.03 14.3 0.1 0.25 11.3 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.7 CCU97349.1 - 0.033 13.8 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 CCU97349.1 - 0.034 13.8 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 CCU97349.1 - 0.034 13.7 0.1 0.096 12.2 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 CCU97349.1 - 0.038 13.0 0.1 0.54 9.3 0.0 2.1 1 1 1 2 2 2 0 KaiC PduV-EutP PF10662.4 CCU97349.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.1 CCU97349.1 - 0.073 11.5 0.0 0.083 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 CCU97349.1 - 0.081 11.5 0.1 0.16 10.6 0.0 1.4 1 1 0 1 1 1 0 Rad17 cell cycle checkpoint protein FtsK_SpoIIIE PF01580.13 CCU97349.1 - 0.087 12.2 0.0 0.69 9.3 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family KTI12 PF08433.5 CCU97349.1 - 0.092 11.9 0.0 0.15 11.2 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Sigma54_activat PF00158.21 CCU97349.1 - 0.092 12.2 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain Cpn60_TCP1 PF00118.19 CCU97349.1 - 0.13 10.8 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Lon_2 PF13337.1 CCU97349.1 - 0.15 10.3 0.0 0.22 9.8 0.0 1.1 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease DUF258 PF03193.11 CCU97349.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Rad51 PF08423.6 CCU97349.1 - 0.16 10.8 0.2 5 5.9 0.0 2.1 1 1 1 2 2 2 0 Rad51 WD40 PF00400.27 CCU97350.1 - 2.4e-30 103.2 0.3 3.5e-07 29.8 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 CCU97350.1 - 0.00018 19.8 0.1 0.00026 19.2 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 eIF2A PF08662.6 CCU97350.1 - 0.014 15.0 2.8 0.23 11.1 0.4 2.9 1 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A PP2C PF00481.16 CCU97351.1 - 3.4e-77 259.3 0.0 4.6e-77 258.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CCU97351.1 - 0.0018 17.6 0.0 0.0043 16.4 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C HlyIII PF03006.15 CCU97352.1 - 1.6e-50 171.6 20.9 2e-50 171.2 14.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related Glyco_transf_4 PF13439.1 CCU97352.1 - 0.029 14.1 0.3 0.082 12.6 0.1 1.8 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Bromo_TP PF07524.8 CCU97353.1 - 9.2e-09 34.9 0.0 1.5e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 CCU97353.1 - 1.1e-06 28.5 1.3 3.2e-06 27.0 0.0 2.4 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Tox-REase-2 PF15646.1 CCU97353.1 - 0.014 15.2 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 2 E1-E2_ATPase PF00122.15 CCU97354.1 - 2.9e-68 229.3 1.8 2.9e-68 229.3 1.2 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCU97354.1 - 8.6e-32 111.2 0.1 3.8e-24 86.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CCU97354.1 - 2.6e-29 102.0 7.4 2.6e-29 102.0 5.2 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 CCU97354.1 - 2.5e-16 58.8 0.0 2.5e-16 58.8 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CCU97354.1 - 1.2e-15 57.2 0.0 2.3e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCU97354.1 - 5.5e-13 49.5 0.0 1.2e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCU97354.1 - 0.00049 19.7 0.1 0.0056 16.2 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rdx PF10262.4 CCU97356.1 - 8.4e-08 32.1 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Rdx family SIR2 PF02146.12 CCU97357.1 - 3.7e-24 85.4 0.0 8.8e-19 67.9 0.0 3.0 3 0 0 3 3 3 2 Sir2 family LZ_Tnp_IS66 PF13007.2 CCU97357.1 - 2.9 8.6 18.1 0.2 12.3 1.3 3.4 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain ETF PF01012.16 CCU97358.1 - 3.7e-41 140.5 5.7 6.9e-41 139.7 4.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 CCU97358.1 - 4.6e-35 119.1 0.4 4.6e-35 119.1 0.3 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Ku PF02735.11 CCU97359.1 - 1.1e-13 51.0 0.0 1.4e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 CCU97359.1 - 0.044 13.6 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Ku C terminal domain like Glyco_trans_1_4 PF13692.1 CCU97360.1 - 1.9e-20 73.3 1.9 5.9e-20 71.7 0.1 2.5 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCU97360.1 - 9e-10 38.9 19.9 9e-10 38.9 13.8 2.4 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 CCU97360.1 - 0.00045 19.6 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CCU97360.1 - 0.0047 17.1 0.5 0.016 15.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Ufd2P_core PF10408.4 CCU97361.1 - 1.3e-168 562.1 0.0 1.5e-168 561.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CCU97361.1 - 4.7e-25 87.3 0.1 1.1e-24 86.1 0.1 1.7 1 0 0 1 1 1 1 U-box domain EIF_2_alpha PF07541.7 CCU97362.1 - 3.3e-42 142.8 0.9 1.3e-41 140.8 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CCU97362.1 - 1.2e-12 47.7 0.2 3.3e-12 46.3 0.1 1.8 1 0 0 1 1 1 1 S1 RNA binding domain DUF4312 PF14189.1 CCU97362.1 - 0.033 13.9 1.2 0.5 10.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4312) EXOSC1 PF10447.4 CCU97362.1 - 0.038 13.9 0.1 0.09 12.7 0.0 1.7 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 DUF2944 PF11161.3 CCU97362.1 - 0.11 12.2 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Cpn60_TCP1 PF00118.19 CCU97363.1 - 2.6e-145 484.7 0.6 3.3e-145 484.4 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.16 CCU97363.1 - 0.002 17.9 0.2 0.033 14.0 0.1 2.5 2 0 0 2 2 2 1 Resolvase, N terminal domain UBN2_2 PF14227.1 CCU97363.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Pro_isomerase PF00160.16 CCU97364.1 - 1e-47 162.2 0.0 2.5e-47 160.9 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CCU97364.1 - 9.9e-09 34.7 0.3 0.027 14.3 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat BCNT PF07572.7 CCU97365.1 - 5.7e-15 55.0 0.9 1.5e-14 53.7 0.6 1.6 1 1 0 1 1 1 1 Bucentaur or craniofacial development Ndc1_Nup PF09531.5 CCU97365.1 - 0.096 11.0 3.7 0.1 10.9 2.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.12 CCU97365.1 - 4 6.1 5.5 4.7 5.9 3.8 1.2 1 0 0 1 1 1 0 Presenilin Semialdhyde_dhC PF02774.13 CCU97366.1 - 1.4e-41 142.3 0.0 1.9e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 CCU97366.1 - 2.1e-13 50.6 0.0 5.9e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 CCU97366.1 - 0.0033 17.9 0.2 0.01 16.3 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 CCU97366.1 - 0.0062 16.4 0.0 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus ILVD_EDD PF00920.16 CCU97367.1 - 9.9e-195 647.8 0.1 1.1e-194 647.6 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Ribosomal_L15e PF00827.12 CCU97370.1 - 3.2e-84 281.2 16.7 1.4e-83 279.0 11.6 1.8 1 1 0 1 1 1 1 Ribosomal L15 Ribosomal_L18p PF00861.17 CCU97371.1 - 1.1e-42 144.9 0.1 5.7e-42 142.6 0.0 2.1 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CCU97371.1 - 1.5e-34 118.3 4.3 1.5e-34 118.3 3.0 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region MtrA PF04208.9 CCU97371.1 - 0.039 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A Thr_synth_N PF14821.1 CCU97371.1 - 0.087 12.8 0.1 18 5.4 0.0 2.6 2 0 0 2 2 2 0 Threonine synthase N terminus His_Phos_2 PF00328.17 CCU97372.1 - 7.1e-76 255.7 2.4 2e-39 135.9 0.1 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.17 CCU97373.1 - 5.4e-85 285.7 0.1 8.9e-47 160.0 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) ERG4_ERG24 PF01222.12 CCU97374.1 - 1.8e-92 310.1 6.5 1.9e-69 234.2 2.2 2.0 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CCU97374.1 - 7.6e-05 22.1 3.6 0.00011 21.6 2.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CCU97374.1 - 9.2e-05 22.5 0.1 0.00026 21.0 0.0 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase Ras PF00071.17 CCU97376.1 - 2.4e-53 179.8 0.0 2.8e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU97376.1 - 3.1e-13 50.2 0.0 4.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCU97376.1 - 2.1e-06 27.0 0.0 3.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCU97376.1 - 0.0013 17.8 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCU97376.1 - 0.004 16.3 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GDA1_CD39 PF01150.12 CCU97377.1 - 1.3e-68 231.5 0.0 2.7e-56 190.9 0.0 2.0 1 1 1 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family DUF1644 PF07800.7 CCU97377.1 - 0.0053 16.6 0.5 0.79 9.5 0.1 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF1644) Ppx-GppA PF02541.11 CCU97377.1 - 0.13 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DcpS_C PF11969.3 CCU97378.1 - 8.6e-26 90.4 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding TFCD_C PF12612.3 CCU97379.1 - 2.2e-24 85.9 0.1 6.7e-24 84.3 0.1 1.8 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal Vac14_Fab1_bd PF12755.2 CCU97379.1 - 0.022 15.1 0.2 8.1 6.9 0.0 3.5 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Hpt PF01627.18 CCU97380.1 - 6.9e-12 45.2 0.6 1.1e-11 44.6 0.1 1.5 2 0 0 2 2 2 1 Hpt domain TPR_16 PF13432.1 CCU97380.1 - 0.022 15.4 2.7 1.7 9.4 0.4 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat PspA_IM30 PF04012.7 CCU97380.1 - 0.07 12.4 0.2 0.53 9.6 0.0 1.9 2 0 0 2 2 2 0 PspA/IM30 family DUF544 PF04424.8 CCU97381.1 - 2.4e-13 49.9 0.0 3.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Ribosomal_S13_N PF08069.7 CCU97381.1 - 0.13 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Peptidase_M24 PF00557.19 CCU97382.1 - 5.5e-25 88.1 0.1 8.1e-25 87.6 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Pkinase PF00069.20 CCU97383.1 - 5.4e-37 127.3 0.0 9.9e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97383.1 - 1.3e-11 44.0 0.0 2.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCU97383.1 - 9.5e-05 22.2 0.1 9.5e-05 22.2 0.1 3.9 3 3 2 5 5 5 1 Phosphotransferase enzyme family Kinetochor_Ybp2 PF08568.5 CCU97383.1 - 0.00065 18.0 0.0 0.0012 17.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Choline_kinase PF01633.15 CCU97383.1 - 0.0033 17.0 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase AAA_2 PF07724.9 CCU97384.1 - 2.2e-46 157.8 0.0 2.1e-42 144.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CCU97384.1 - 2.5e-26 91.3 2.4 3.9e-26 90.7 0.1 2.6 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 CCU97384.1 - 1.1e-18 67.6 0.0 2.7e-09 37.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCU97384.1 - 8.2e-13 48.2 0.1 1.5e-07 31.2 0.0 3.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCU97384.1 - 4.5e-09 36.5 1.7 0.0034 17.5 0.0 4.0 3 1 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 CCU97384.1 - 5.7e-09 35.6 0.2 1.1e-06 28.2 0.1 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 CCU97384.1 - 1.5e-08 34.8 9.0 0.00022 21.2 0.0 4.9 3 2 1 5 5 5 2 AAA ATPase domain AAA_14 PF13173.1 CCU97384.1 - 7.2e-07 29.1 0.0 0.028 14.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CCU97384.1 - 8e-05 22.1 0.3 0.095 12.1 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 CCU97384.1 - 0.0001 22.0 1.3 0.033 13.8 0.1 3.4 3 1 0 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 CCU97384.1 - 0.00015 22.0 0.2 0.94 9.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 CCU97384.1 - 0.00036 19.7 1.2 1.7 7.7 0.1 3.7 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CCU97384.1 - 0.00051 20.1 0.0 0.47 10.6 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_17 PF13207.1 CCU97384.1 - 0.00061 20.5 2.1 0.67 10.7 0.2 4.0 3 1 0 3 3 3 1 AAA domain SRP54 PF00448.17 CCU97384.1 - 0.0012 18.3 0.0 1.5 8.2 0.0 2.6 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_19 PF13245.1 CCU97384.1 - 0.0013 18.4 0.0 0.27 10.9 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 CCU97384.1 - 0.0019 18.1 1.0 2.2 8.2 0.0 4.0 3 1 1 4 4 3 1 AAA domain Zeta_toxin PF06414.7 CCU97384.1 - 0.0054 15.8 0.0 0.49 9.4 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 CCU97384.1 - 0.0064 16.1 0.0 0.29 10.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain TrwB_AAD_bind PF10412.4 CCU97384.1 - 0.0098 14.5 0.2 6.2 5.3 0.0 3.1 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 CCU97384.1 - 0.01 15.4 1.6 0.21 11.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 CCU97384.1 - 0.017 14.8 0.0 0.42 10.3 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 CCU97384.1 - 0.034 13.7 0.1 0.46 10.0 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IncA PF04156.9 CCU97384.1 - 0.035 13.7 9.7 0.1 12.2 6.7 1.7 1 0 0 1 1 1 0 IncA protein UPF0079 PF02367.12 CCU97384.1 - 0.06 12.9 0.0 14 5.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DNA_pol3_delta2 PF13177.1 CCU97384.1 - 0.1 12.2 0.1 4 7.0 0.0 3.2 3 1 0 3 3 3 0 DNA polymerase III, delta subunit DUF258 PF03193.11 CCU97384.1 - 0.11 11.6 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 CCU97384.1 - 0.15 11.6 0.1 17 4.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CCU97384.1 - 0.32 11.2 6.7 1.6e+02 2.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain Atg14 PF10186.4 CCU97384.1 - 0.57 9.0 6.0 1.1 8.1 4.1 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Macoilin PF09726.4 CCU97384.1 - 5 5.2 7.7 7.4 4.7 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein BCIP PF13862.1 CCU97385.1 - 8.7e-38 129.7 0.0 1.2e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein NIF PF03031.13 CCU97386.1 - 1.2e-51 174.5 0.2 2e-51 173.8 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PRK PF00485.13 CCU97387.1 - 0.032 13.7 0.0 0.045 13.2 0.0 1.3 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF2303 PF10065.4 CCU97387.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) CHCH PF06747.8 CCU97388.1 - 7.9e-05 22.4 3.9 0.00011 21.9 2.7 1.3 1 0 0 1 1 1 1 CHCH domain Succ_CoA_lig PF13607.1 CCU97388.1 - 0.039 13.5 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Nucleoporin_FG PF13634.1 CCU97388.1 - 0.059 13.6 1.7 0.082 13.1 1.2 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeat region DUF663 PF04950.7 CCU97389.1 - 9.7e-88 293.9 0.0 9.7e-88 293.9 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CCU97389.1 - 4.9e-30 102.8 0.0 2e-29 100.9 0.0 2.1 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CCU97389.1 - 3.2e-06 26.7 0.0 0.00032 20.1 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CCU97389.1 - 2.8e-05 24.1 0.0 2.8e-05 24.1 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain MobB PF03205.9 CCU97389.1 - 2.9e-05 23.7 0.2 8.5e-05 22.2 0.1 1.8 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 CCU97389.1 - 0.00012 22.1 0.0 0.0004 20.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CCU97389.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 CCU97389.1 - 0.0036 17.5 0.0 0.0085 16.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CCU97389.1 - 0.0047 16.6 1.0 0.0088 15.7 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase ABC_tran PF00005.22 CCU97389.1 - 0.0048 17.2 1.7 0.011 16.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter PduV-EutP PF10662.4 CCU97389.1 - 0.0053 16.2 0.0 0.017 14.5 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 CCU97389.1 - 0.0062 17.3 0.0 0.0062 17.3 0.0 4.0 4 1 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 CCU97389.1 - 0.0081 16.3 0.0 0.034 14.3 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 CCU97389.1 - 0.0097 15.8 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CCU97389.1 - 0.031 14.2 0.1 0.13 12.2 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 CCU97389.1 - 0.035 13.9 2.9 0.11 12.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CCU97389.1 - 0.058 12.9 3.0 0.096 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 CCU97389.1 - 0.08 12.3 0.0 0.24 10.8 0.0 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 CCU97389.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 CCU97389.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 CCU97389.1 - 0.19 12.2 3.2 0.25 11.8 0.0 2.8 3 1 1 4 4 2 0 Miro-like protein Hom_end_hint PF05203.11 CCU97389.1 - 1.7 8.3 7.2 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 Hom_end-associated Hint AAA_23 PF13476.1 CCU97389.1 - 7.3 6.8 0.0 7.3 6.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain Nipped-B_C PF12830.2 CCU97390.1 - 5.9e-31 107.5 3.0 1.8e-26 92.9 0.3 2.3 1 1 1 2 2 2 2 Sister chromatid cohesion C-terminus Myc_target_1 PF15179.1 CCU97391.1 - 0.028 14.0 0.4 0.065 12.8 0.3 1.5 1 0 0 1 1 1 0 Myc target protein 1 OPT PF03169.10 CCU97392.1 - 6.2e-152 507.2 38.4 7.7e-152 506.9 26.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Hydrolase_6 PF13344.1 CCU97393.1 - 3.2e-20 71.8 0.0 8.9e-20 70.4 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCU97393.1 - 1.3e-15 56.8 0.0 8e-15 54.3 0.0 2.2 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCU97393.1 - 0.049 14.0 0.0 0.12 12.7 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HA2 PF04408.18 CCU97396.1 - 6.1e-20 71.1 0.4 4.3e-19 68.4 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCU97396.1 - 6.3e-13 48.3 0.0 1.8e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CCU97396.1 - 2.2e-09 37.1 0.0 7.8e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CCU97396.1 - 2.8e-07 30.1 0.0 7.2e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCU97396.1 - 3.1e-06 27.3 0.0 9.4e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCU97396.1 - 0.0051 16.5 0.0 0.02 14.6 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 CCU97396.1 - 0.0062 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 KaiC FtsK_SpoIIIE PF01580.13 CCU97396.1 - 0.0096 15.4 0.0 0.028 13.9 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 CCU97396.1 - 0.01 14.7 0.0 0.023 13.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 CCU97396.1 - 0.014 15.7 0.0 0.014 15.7 0.0 2.4 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.4 CCU97396.1 - 0.018 14.0 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CCU97396.1 - 0.15 11.8 5.4 0.83 9.4 0.0 3.5 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit vATP-synt_AC39 PF01992.11 CCU97397.1 - 3.4e-97 325.6 0.0 4.1e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Acyl_CoA_thio PF02551.10 CCU97397.1 - 0.16 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA thioesterase Hist_deacetyl PF00850.14 CCU97398.1 - 1.7e-55 188.5 0.1 2.2e-55 188.1 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RRM_1 PF00076.17 CCU97400.1 - 1.4e-09 37.4 0.0 2.9e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU97400.1 - 4.1e-09 36.1 0.0 6.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU97400.1 - 8e-06 25.7 0.0 2e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.14 CCU97400.1 - 0.071 13.5 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribosomal_S19e PF01090.14 CCU97401.1 - 1.4e-47 160.6 0.0 1.6e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Dicty_REP PF05086.7 CCU97401.1 - 0.21 9.3 7.9 0.22 9.2 5.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NOA36 PF06524.7 CCU97401.1 - 3 7.0 8.1 3.5 6.8 5.6 1.1 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 CCU97401.1 - 3.3 7.2 10.5 4.1 6.9 7.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region HR1 PF02185.11 CCU97402.1 - 1.1e-13 50.7 11.2 6e-09 35.5 0.2 2.3 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 CCU97402.1 - 2.3e-12 46.4 13.2 3.2e-10 39.5 4.9 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CCU97402.1 - 0.0078 15.9 5.2 0.017 14.8 3.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Tropomyosin PF00261.15 CCU97402.1 - 0.72 8.8 4.2 3.6 6.5 0.6 2.3 2 1 0 2 2 2 0 Tropomyosin AAA_11 PF13086.1 CCU97403.1 - 3.8e-66 223.0 0.4 6.3e-66 222.3 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 CCU97403.1 - 6.8e-58 195.3 0.0 1e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.2 CCU97403.1 - 6.6e-19 67.4 0.0 9.7e-19 66.9 0.0 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_19 PF13245.1 CCU97403.1 - 2e-12 46.6 0.7 2e-12 46.6 0.5 3.4 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 CCU97403.1 - 3.9e-09 36.3 3.0 1.4e-06 28.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 CCU97403.1 - 7.2e-08 32.2 0.1 0.056 12.9 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CCU97403.1 - 0.00026 20.4 0.0 0.0016 17.8 0.0 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 CCU97403.1 - 0.00057 20.0 0.2 0.0052 16.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain OmpH PF03938.9 CCU97403.1 - 0.032 14.1 0.3 0.093 12.6 0.2 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA PF00004.24 CCU97403.1 - 0.045 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Aldedh PF00171.17 CCU97403.1 - 0.091 11.0 1.5 0.15 10.3 1.0 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family UvrD_C_2 PF13538.1 CCU97403.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DEAD PF00270.24 CCU97403.1 - 0.12 11.8 0.1 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.1 CCU97403.1 - 0.54 10.5 0.0 1.4 9.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain CPSF_A PF03178.10 CCU97404.1 - 7.1e-30 104.1 0.0 1.2e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region Porin_3 PF01459.17 CCU97406.1 - 2.3e-60 204.2 0.4 2.5e-60 204.0 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Endosulfine PF04667.12 CCU97407.1 - 1.1e-21 76.5 0.1 1.7e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region HLH PF00010.21 CCU97408.1 - 3.2e-18 65.1 0.7 6.7e-18 64.1 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CytochromB561_N PF09786.4 CCU97408.1 - 0.055 11.9 0.1 0.074 11.4 0.1 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Helicase_C PF00271.26 CCU97409.1 - 2.2e-14 53.0 0.0 4.2e-12 45.7 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 CCU97409.1 - 1.6e-07 30.9 0.1 3.8e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 CCU97409.1 - 0.00055 19.6 0.0 0.002 17.7 0.0 2.0 1 1 0 1 1 1 1 RQC domain Peptidase_M22 PF00814.20 CCU97410.1 - 1.3e-19 70.7 0.0 1.4e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family tRNA-synt_2b PF00587.20 CCU97411.1 - 6.4e-18 64.9 0.1 1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCU97411.1 - 1.7e-06 27.8 0.0 3.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 CCU97411.1 - 0.017 13.9 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) NAD_binding_10 PF13460.1 CCU97412.1 - 3.1e-09 37.0 0.0 4.5e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CCU97412.1 - 2.6e-06 26.5 0.0 7.5e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 CCU97412.1 - 2.6e-05 23.3 0.0 0.011 14.6 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein Epimerase PF01370.16 CCU97412.1 - 0.00058 19.3 0.0 0.014 14.8 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCU97412.1 - 0.14 10.8 0.0 2.1 6.9 0.0 2.2 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CCU97413.1 - 3.5e-05 23.1 0.0 4.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 CCU97413.1 - 4.1e-05 22.6 0.1 5.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CCU97413.1 - 0.00047 19.6 0.1 0.00076 18.9 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCU97413.1 - 0.00075 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CCU97413.1 - 0.0052 15.5 0.0 0.0065 15.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CCU97413.1 - 0.029 14.2 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 CCU97413.1 - 0.068 12.0 0.0 0.092 11.6 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain WD40 PF00400.27 CCU97414.1 - 1.5e-16 59.5 1.7 0.00011 21.9 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF1681 PF07933.9 CCU97415.1 - 3.1e-50 169.8 0.0 3.6e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CcmD PF04995.9 CCU97416.1 - 0.02 14.5 1.5 0.046 13.4 1.1 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) POP1 PF06978.6 CCU97417.1 - 2e-37 128.7 16.4 2e-36 125.3 11.4 2.2 1 1 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 CCU97417.1 - 2.8e-16 59.1 0.0 6e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 POPLD (NUC188) domain Abhydrolase_5 PF12695.2 CCU97418.1 - 8.4e-07 28.8 0.0 0.003 17.2 0.0 2.7 2 2 0 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 CCU97418.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCU97419.1 - 4.3e-07 29.7 0.0 7.7e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCU97419.1 - 0.0026 17.6 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Plasmodium_HRP PF05403.6 CCU97420.1 - 5.5e-08 32.6 16.4 5.5e-08 32.6 11.4 1.9 2 0 0 2 2 2 1 Plasmodium histidine-rich protein (HRPII/III) Tyr-DNA_phospho PF06087.7 CCU97421.1 - 3.2e-40 138.1 0.0 4.6e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 CCU97421.1 - 2.1e-07 30.7 0.0 0.00017 21.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain TFIIE_beta PF02186.10 CCU97421.1 - 0.062 13.2 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 TFIIE beta subunit core domain Pkinase PF00069.20 CCU97422.1 - 7.8e-66 221.8 0.0 1e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97422.1 - 2.6e-25 89.0 0.0 3.6e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCU97422.1 - 0.038 13.7 0.4 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family FUSC PF04632.7 CCU97424.1 - 0.86 7.9 12.0 1.1 7.6 8.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PV-1 PF06637.6 CCU97424.1 - 4.9 5.6 15.7 6.6 5.1 10.9 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) CK_II_beta PF01214.13 CCU97425.1 - 9.6e-57 191.4 0.0 1.1e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Na_H_Exchanger PF00999.16 CCU97426.1 - 3.7e-30 104.7 0.6 3.2e-20 71.9 3.2 2.0 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family DUF2839 PF10999.3 CCU97426.1 - 0.12 12.4 2.2 0.18 11.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) Na_H_Exchanger PF00999.16 CCU97427.1 - 3.6e-10 38.9 2.5 1.5e-09 36.8 1.8 1.7 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Tom22 PF04281.8 CCU97428.1 - 9.4e-42 141.7 0.9 1.1e-41 141.5 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Cir_N PF10197.4 CCU97428.1 - 0.57 10.2 2.3 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF2201_N PF13203.1 CCU97429.1 - 0.53 9.4 6.8 0.028 13.5 0.5 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain Fcf2 PF08698.6 CCU97430.1 - 4.2e-10 39.5 0.0 1.2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing XRCC4 PF06632.7 CCU97430.1 - 0.35 9.6 4.6 0.45 9.3 3.2 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Sas10 PF09368.5 CCU97431.1 - 8.4e-26 89.9 4.4 2.2e-25 88.6 3.1 1.7 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CCU97431.1 - 0.0082 16.3 0.1 0.025 14.7 0.1 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Chisel PF15355.1 CCU97431.1 - 1.5 8.8 6.0 6.9 6.7 1.0 3.0 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel WD40 PF00400.27 CCU97432.1 - 2.7e-16 58.7 9.3 1.4e-06 27.9 0.1 5.3 5 1 0 5 5 5 4 WD domain, G-beta repeat Rax2 PF12768.2 CCU97432.1 - 0.0037 16.5 0.0 0.0089 15.2 0.0 1.5 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Apc4_WD40 PF12894.2 CCU97432.1 - 0.033 13.6 0.0 2 7.9 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain COX8 PF02285.10 CCU97432.1 - 0.038 13.5 0.1 0.13 11.7 0.0 1.9 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII Pho88 PF10032.4 CCU97433.1 - 1.4e-66 223.4 0.2 1.6e-66 223.2 0.1 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) Cullin PF00888.17 CCU97434.1 - 1.8e-168 561.7 0.4 2.3e-168 561.4 0.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CCU97434.1 - 4.1e-22 77.7 2.3 1.9e-21 75.6 1.6 2.2 1 1 0 1 1 1 1 Cullin protein neddylation domain HTH_27 PF13463.1 CCU97434.1 - 0.047 14.0 0.3 4.2 7.7 0.0 3.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain RRM_6 PF14259.1 CCU97436.1 - 2.1e-46 155.7 0.0 2.4e-17 62.6 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCU97436.1 - 5.1e-41 138.1 0.0 1.3e-16 59.9 0.0 4.8 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU97436.1 - 3.7e-16 58.6 0.0 1.9e-07 30.8 0.0 3.9 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCU97436.1 - 8.8e-11 41.4 0.0 0.0042 16.8 0.0 3.8 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.1 CCU97436.1 - 0.24 10.8 0.0 20 4.6 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4651) DUF2373 PF10180.4 CCU97437.1 - 1e-13 50.5 1.4 4.3e-09 35.7 1.4 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) LZ_Tnp_IS66 PF13007.2 CCU97437.1 - 2.2 8.9 14.9 0.4 11.3 4.6 2.9 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain DUF2360 PF10152.4 CCU97437.1 - 9.3 6.5 11.5 10 6.4 0.5 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) OB_NTP_bind PF07717.11 CCU97438.1 - 9.3e-15 54.4 0.0 2.6e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CCU97438.1 - 8.5e-13 48.2 0.0 1.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCU97438.1 - 2.5e-11 43.2 0.0 1.6e-10 40.7 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCU97438.1 - 4.6e-07 29.4 0.1 0.011 15.1 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.1 CCU97438.1 - 5.2e-07 29.8 0.1 6.1e-06 26.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 CCU97438.1 - 0.00014 21.7 0.0 0.078 12.8 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit KaiC PF06745.8 CCU97438.1 - 0.017 14.2 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 CCU97438.1 - 0.017 14.0 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 CCU97438.1 - 0.041 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 CCU97438.1 - 0.07 12.3 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 CCU97438.1 - 0.091 13.0 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 1 0 ABC transporter HECT PF00632.20 CCU97439.1 - 5e-27 94.8 0.0 1.6e-19 70.1 0.0 2.2 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) CDC45 PF02724.9 CCU97439.1 - 0.2 9.6 7.4 2.1 6.2 4.7 2.2 2 0 0 2 2 2 0 CDC45-like protein Spore_coat_CotO PF14153.1 CCU97439.1 - 1.4 8.3 9.1 2.8 7.3 6.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO IQ PF00612.22 CCU97439.1 - 2.9 7.7 6.1 0.22 11.2 0.6 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif Miro PF08477.8 CCU97440.1 - 1.9e-36 125.1 0.0 1.8e-19 70.4 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 CCU97440.1 - 3.4e-31 107.8 0.0 3.6e-21 75.2 0.0 2.1 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.7 CCU97440.1 - 8.2e-27 92.3 0.1 2.2e-26 90.9 0.0 1.8 2 0 0 2 2 1 1 EF hand associated EF_assoc_2 PF08356.7 CCU97440.1 - 5.1e-26 90.2 0.0 9.3e-26 89.4 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF-hand_6 PF13405.1 CCU97440.1 - 1.4e-09 37.0 0.7 0.00031 20.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CCU97440.1 - 4e-09 35.1 0.3 0.0015 17.6 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 CCU97440.1 - 2.1e-08 33.1 0.2 0.0089 15.3 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CCU97440.1 - 3.8e-08 33.3 0.1 0.00059 19.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair MMR_HSR1 PF01926.18 CCU97440.1 - 6.6e-07 29.2 0.0 0.0048 16.8 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 CCU97440.1 - 4.5e-06 26.8 0.0 0.059 13.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCU97440.1 - 6.3e-05 23.0 0.0 0.05 13.5 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain EF-hand_8 PF13833.1 CCU97440.1 - 0.00013 21.5 1.6 0.51 9.9 0.0 2.9 3 0 0 3 3 2 2 EF-hand domain pair cobW PF02492.14 CCU97440.1 - 0.00058 19.3 0.3 1.2 8.5 0.0 3.9 2 2 2 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 CCU97440.1 - 0.00082 18.9 0.0 0.052 13.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 CCU97440.1 - 0.0013 18.4 0.0 0.79 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SRPRB PF09439.5 CCU97440.1 - 0.002 17.3 0.0 1.1 8.4 0.0 2.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 CCU97440.1 - 0.002 17.3 0.0 0.25 10.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CCU97440.1 - 0.0041 16.6 0.0 0.24 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 CCU97440.1 - 0.0041 16.8 0.0 0.8 9.5 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 CCU97440.1 - 0.0045 17.2 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 CCU97440.1 - 0.0056 16.2 0.0 2.7 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain EF-hand_10 PF14788.1 CCU97440.1 - 0.0071 15.9 0.4 0.39 10.4 0.1 2.4 2 0 0 2 2 2 1 EF hand FtsK_SpoIIIE PF01580.13 CCU97440.1 - 0.008 15.6 0.0 0.12 11.8 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.24 CCU97440.1 - 0.0095 16.1 0.0 6 7.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCU97440.1 - 0.011 15.4 0.0 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain SPARC_Ca_bdg PF10591.4 CCU97440.1 - 0.015 15.2 0.4 2.8 8.0 0.0 3.2 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region AAA_28 PF13521.1 CCU97440.1 - 0.019 14.9 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CCU97440.1 - 0.021 14.2 0.0 0.39 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CCU97440.1 - 0.021 15.6 0.0 1.4 9.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CCU97440.1 - 0.024 14.4 0.0 0.3 10.9 0.0 2.4 2 1 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 CCU97440.1 - 0.032 14.1 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CCU97440.1 - 0.041 13.4 0.1 12 5.2 0.0 3.3 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 CCU97440.1 - 0.051 13.1 0.0 3.2 7.3 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 CCU97440.1 - 0.06 12.7 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 1 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.7 CCU97440.1 - 0.078 12.0 0.0 3 6.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin FeoB_N PF02421.13 CCU97440.1 - 0.081 12.2 0.0 9.9 5.4 0.0 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.1 CCU97440.1 - 0.1 12.9 0.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CCU97440.1 - 0.14 12.3 0.0 28 4.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Guanylate_kin PF00625.16 CCU97440.1 - 0.18 11.2 0.0 4.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase Septin PF00735.13 CCU97440.1 - 0.2 10.6 0.0 2 7.3 0.0 2.1 2 0 0 2 2 2 0 Septin AIG1 PF04548.11 CCU97440.1 - 0.21 10.6 0.1 0.76 8.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family MCM PF00493.18 CCU97440.1 - 0.24 10.1 0.0 3.8 6.2 0.0 2.1 2 0 0 2 2 2 0 MCM2/3/5 family DUF2075 PF09848.4 CCU97440.1 - 0.3 10.0 0.0 1.3 7.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sulfate_transp PF00916.15 CCU97441.1 - 3.5e-11 42.6 2.1 3.5e-11 42.6 1.5 3.2 3 1 0 3 3 3 1 Sulfate transporter family Peptidase_C48 PF02902.14 CCU97442.1 - 3.7e-08 33.2 0.0 5.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ldh_1_C PF02866.13 CCU97443.1 - 6.5e-42 143.2 0.0 1.1e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CCU97443.1 - 3.1e-29 101.5 1.5 5.4e-27 94.3 0.0 2.3 1 1 1 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 CCU97443.1 - 0.14 11.4 0.1 0.35 10.1 0.1 1.6 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase Malic_M PF03949.10 CCU97444.1 - 3.7e-82 275.6 0.0 4.7e-82 275.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CCU97444.1 - 2.5e-66 222.7 0.0 4.6e-66 221.8 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Shikimate_DH PF01488.15 CCU97444.1 - 0.038 14.0 0.2 0.31 11.1 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DEAD PF00270.24 CCU97445.1 - 9.6e-22 77.2 0.0 1.5e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU97445.1 - 2.4e-12 46.5 0.0 2.9e-11 43.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.6 CCU97445.1 - 0.0013 18.7 0.1 0.0057 16.6 0.1 2.0 2 0 0 2 2 2 1 DNA replication factor CDT1 like PRP1_N PF06424.7 CCU97446.1 - 1.5e-49 167.7 5.1 1.5e-49 167.7 3.5 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 CCU97446.1 - 5.9e-23 79.2 45.7 0.00064 20.1 0.3 14.2 9 5 6 15 15 14 8 Tetratricopeptide repeat TPR_19 PF14559.1 CCU97446.1 - 7.6e-15 55.0 16.9 0.021 15.1 0.7 9.3 8 3 3 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 CCU97446.1 - 1.4e-10 41.5 31.6 0.00073 20.1 1.9 8.0 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCU97446.1 - 5.5e-09 35.5 3.6 7.5e-05 22.2 0.7 6.4 7 0 0 7 7 7 1 TPR repeat TPR_2 PF07719.12 CCU97446.1 - 1.3e-07 31.0 3.1 0.033 14.1 0.1 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCU97446.1 - 3.8e-07 29.9 15.3 0.0018 18.1 1.1 7.0 8 1 0 8 8 8 3 Tetratricopeptide repeat Suf PF05843.9 CCU97446.1 - 3.4e-05 23.7 0.0 0.13 11.9 0.0 4.5 5 0 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_6 PF13174.1 CCU97446.1 - 0.00099 19.4 4.5 20 5.8 0.0 6.5 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCU97446.1 - 0.0022 17.5 0.1 0.14 11.7 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCU97446.1 - 0.037 14.2 0.1 4.8 7.6 0.0 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCU97446.1 - 0.048 13.5 16.9 0.058 13.2 2.6 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TBCA PF02970.11 CCU97446.1 - 0.76 9.8 8.3 2.2 8.3 2.5 3.0 2 0 0 2 2 2 0 Tubulin binding cofactor A HSF_DNA-bind PF00447.12 CCU97447.1 - 2.2e-17 63.1 0.0 4e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding SCO1-SenC PF02630.9 CCU97448.1 - 6.2e-56 188.7 0.0 8.5e-56 188.2 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Tcf25 PF04910.9 CCU97449.1 - 8.7e-73 245.3 0.0 1.2e-72 244.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Ferrochelatase PF00762.14 CCU97450.1 - 2.2e-104 348.8 0.0 2.5e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Xpo1 PF08389.7 CCU97451.1 - 3.6e-09 36.6 0.1 4.5e-08 33.1 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_C PF08767.6 CCU97451.1 - 0.045 12.6 0.0 0.085 11.7 0.0 1.4 1 0 0 1 1 1 0 CRM1 C terminal F-actin_cap_A PF01267.12 CCU97452.1 - 2.8e-65 220.0 0.0 3.4e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Pet127 PF08634.5 CCU97453.1 - 1.1e-84 283.8 0.0 1.5e-84 283.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Ribosomal_L6e PF01159.14 CCU97454.1 - 9.2e-38 128.8 0.1 1.5e-37 128.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 CCU97454.1 - 0.028 14.3 0.3 0.028 14.3 0.2 2.1 3 0 0 3 3 3 0 Ribosomal protein L6, N-terminal domain Mur_ligase_M PF08245.7 CCU97455.1 - 0.00028 21.0 0.0 0.014 15.4 0.0 3.0 1 1 0 1 1 1 1 Mur ligase middle domain Mmp37 PF09139.6 CCU97456.1 - 8.3e-91 304.4 0.0 1.2e-90 303.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 DUF500 PF04366.7 CCU97458.1 - 2.8e-38 130.1 0.2 4.3e-38 129.6 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Calcipressin PF04847.7 CCU97459.1 - 1.5e-24 86.5 3.6 2.9e-24 85.6 0.6 2.4 2 1 0 2 2 2 1 Calcipressin Voldacs PF03517.8 CCU97459.1 - 5.9e-20 71.4 7.1 2.1e-19 69.7 4.9 1.9 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling RRM_5 PF13893.1 CCU97459.1 - 0.2 11.5 0.0 0.45 10.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L36e PF01158.13 CCU97460.1 - 2.6e-30 104.2 2.0 1e-19 70.2 0.0 2.0 2 0 0 2 2 2 2 Ribosomal protein L36e eIF3_N PF09440.5 CCU97461.1 - 1e-30 106.6 3.4 1.8e-30 105.7 2.4 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 CCU97461.1 - 0.00071 19.8 0.4 0.0026 18.0 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.1 CCU97461.1 - 0.015 15.6 4.0 0.044 14.1 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 CCU97461.1 - 0.054 13.6 1.4 0.24 11.5 0.9 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCU97461.1 - 1 9.3 3.6 0.51 10.2 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_28 PF02636.12 CCU97462.1 - 1.6e-65 221.0 0.0 2e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RNA_pol_I_A49 PF06870.7 CCU97463.1 - 8.6e-68 228.6 0.0 1.2e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor HTH_6 PF01418.12 CCU97463.1 - 0.069 12.8 0.2 0.92 9.2 0.0 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family Arf PF00025.16 CCU97464.1 - 1e-79 265.7 0.1 1.2e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCU97464.1 - 6.2e-14 51.6 0.0 7.7e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CCU97464.1 - 6.8e-13 48.3 0.0 7.3e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CCU97464.1 - 5.2e-12 45.1 1.0 7.8e-09 34.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCU97464.1 - 2.9e-11 42.9 0.0 3.3e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCU97464.1 - 7.1e-09 36.2 0.0 9.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCU97464.1 - 6.5e-06 26.0 0.0 8.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CCU97464.1 - 0.0063 15.6 0.2 0.018 14.1 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CCU97464.1 - 0.018 14.4 0.0 0.12 11.8 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CCU97464.1 - 0.087 12.6 0.1 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain PRT_C PF08372.5 CCU97465.1 - 2.5e-06 27.0 3.8 1e-05 25.0 0.3 2.6 1 1 1 2 2 2 2 Plant phosphoribosyltransferase C-terminal DUF3292 PF11696.3 CCU97465.1 - 3.1e-06 25.3 8.7 0.00019 19.4 0.5 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3292) Reticulon PF02453.12 CCU97465.1 - 0.029 13.9 3.0 0.32 10.5 0.2 2.2 2 0 0 2 2 2 0 Reticulon GMC_oxred_N PF00732.14 CCU97466.1 - 3.3e-45 154.5 0.0 5.7e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCU97466.1 - 5.1e-35 120.8 0.1 9.7e-35 119.9 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCU97466.1 - 3.3e-07 29.5 0.0 1.2e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCU97466.1 - 6e-05 22.9 0.4 0.00023 21.1 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCU97466.1 - 6.8e-05 21.8 9.2 0.0046 15.8 1.4 2.8 2 1 1 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.7 CCU97466.1 - 0.00013 21.0 0.2 0.00021 20.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 CCU97466.1 - 0.00014 21.0 0.1 0.00058 19.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CCU97466.1 - 0.0012 18.7 0.1 0.003 17.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCU97466.1 - 0.0085 16.4 0.2 0.018 15.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCU97466.1 - 0.021 13.9 0.1 0.043 12.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 CCU97466.1 - 0.077 12.7 0.2 0.59 9.8 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 CCU97466.1 - 0.11 10.8 0.3 0.19 10.1 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 CCU97466.1 - 0.14 12.2 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 1 0 TrkA-N domain AIRC PF00731.15 CCU97467.1 - 4.4e-62 207.8 4.7 7e-62 207.1 2.7 1.8 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.17 CCU97467.1 - 2.5e-54 183.2 0.0 3.8e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 CCU97467.1 - 4.4e-16 59.1 0.0 9.1e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCU97467.1 - 1.2e-05 24.2 0.0 0.0007 18.4 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 CCU97467.1 - 0.00033 20.0 0.0 0.0025 17.2 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CoA_binding_2 PF13380.1 CCU97467.1 - 0.85 9.8 5.5 10 6.2 0.0 3.5 3 1 1 4 4 4 0 CoA binding domain LRR_6 PF13516.1 CCU97468.1 - 6.1e-05 22.6 0.4 0.29 11.3 0.0 4.1 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.2 CCU97468.1 - 0.022 14.3 0.0 0.86 9.2 0.0 3.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCU97468.1 - 0.043 13.8 0.0 63 4.1 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat zf-CCCH PF00642.19 CCU97469.1 - 2.7e-05 23.7 1.3 2.7e-05 23.7 0.9 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CCU97469.1 - 0.71 9.9 11.7 3.1 7.9 0.2 3.1 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Sec6 PF06046.8 CCU97470.1 - 2.4e-111 372.6 0.1 3.8e-111 371.9 0.1 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 GDA1_CD39 PF01150.12 CCU97471.1 - 6e-91 305.1 0.0 9.6e-91 304.4 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4381 PF14316.1 CCU97471.1 - 0.073 13.1 2.2 0.19 11.8 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Ppx-GppA PF02541.11 CCU97471.1 - 0.099 11.8 0.0 0.23 10.6 0.0 1.5 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Gemini_mov PF01708.11 CCU97471.1 - 0.1 12.1 1.8 0.23 11.0 0.4 2.2 2 0 0 2 2 2 0 Geminivirus putative movement protein Ras PF00071.17 CCU97472.1 - 9.4e-31 106.3 0.0 1.2e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU97472.1 - 1.2e-07 32.2 0.0 1.8e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCU97472.1 - 0.0016 17.7 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 CCU97472.1 - 0.0084 15.3 0.0 0.016 14.4 0.0 1.4 1 1 1 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CCU97472.1 - 0.014 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF1366 PF07104.6 CCU97472.1 - 0.075 12.6 0.0 0.099 12.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1366) HSP70 PF00012.15 CCU97473.1 - 1.2e-266 885.4 14.5 1.4e-266 885.2 10.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCU97473.1 - 1.6e-19 69.6 0.5 3.8e-17 61.8 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 CCU97473.1 - 7.2e-06 25.3 3.5 0.027 13.5 0.2 3.3 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase FGGY_C PF02782.11 CCU97473.1 - 0.0077 15.8 0.0 0.035 13.7 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain HAP1_N PF04849.8 CCU97473.1 - 0.014 14.3 4.9 0.027 13.4 3.4 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FtsA PF14450.1 CCU97473.1 - 0.043 13.6 3.9 0.39 10.5 0.4 3.5 2 2 0 2 2 2 0 Cell division protein FtsA CP12 PF02672.10 CCU97473.1 - 0.44 11.0 9.2 1.2 9.6 2.7 2.7 2 0 0 2 2 2 0 CP12 domain ScpA_ScpB PF02616.9 CCU97473.1 - 1.2 8.6 11.4 0.055 13.0 2.7 2.1 2 0 0 2 2 2 0 ScpA/B protein HUN PF08729.5 CCU97474.1 - 2.5e-12 46.4 0.0 9e-12 44.6 0.0 2.0 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 CCU97474.1 - 1.4e-11 44.5 0.2 2.1e-11 43.8 0.2 1.2 1 0 0 1 1 1 1 Ubinuclein conserved middle domain DAO PF01266.19 CCU97475.1 - 2.9e-49 167.8 0.0 5.2e-49 167.0 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCU97475.1 - 2e-09 37.6 0.0 4.3e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCU97475.1 - 8.7e-09 34.7 0.2 0.00058 18.8 0.3 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CCU97475.1 - 1.1e-08 34.3 4.2 1.8e-07 30.4 2.9 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CCU97475.1 - 3.9e-07 29.9 0.2 8.2e-06 25.7 0.0 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCU97475.1 - 7.9e-05 22.8 0.0 0.048 13.7 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CCU97475.1 - 8.2e-05 21.8 0.1 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CCU97475.1 - 8.9e-05 22.8 0.4 0.00033 20.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CCU97475.1 - 0.00034 20.3 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 CCU97475.1 - 0.00035 19.1 0.4 0.004 15.6 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein TrkA_N PF02254.13 CCU97475.1 - 0.00038 20.4 0.0 0.00092 19.1 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain ThiF PF00899.16 CCU97475.1 - 0.0044 16.8 0.2 0.0079 16.0 0.1 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 CCU97475.1 - 0.0055 16.9 0.0 0.0099 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 CCU97475.1 - 0.0057 16.4 0.4 3.3 7.4 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding ApbA PF02558.11 CCU97475.1 - 0.0059 16.0 0.3 0.012 15.0 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 CCU97475.1 - 0.0087 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 CCU97475.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 CCU97475.1 - 0.017 14.1 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 CCU97475.1 - 0.024 13.7 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.19 CCU97475.1 - 0.03 13.3 0.1 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 CCU97475.1 - 0.094 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 CCU97475.1 - 0.098 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding F420_oxidored PF03807.12 CCU97475.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.7 CCU97475.1 - 0.17 10.7 0.1 0.27 10.1 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Acyl-CoA_dh_1 PF00441.19 CCU97476.1 - 2e-29 102.6 0.5 3.3e-29 101.9 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 CCU97476.1 - 6.8e-18 64.2 0.0 1.4e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 CCU97476.1 - 4.2e-17 61.3 0.2 7.9e-17 60.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CCU97476.1 - 4.7e-15 56.1 0.0 1.2e-14 54.8 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CCU97476.1 - 0.00017 21.8 0.0 0.0003 21.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Clat_adaptor_s PF01217.15 CCU97477.1 - 1.7e-42 144.5 0.8 1.1e-31 109.5 0.6 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Arf PF00025.16 CCU97477.1 - 2.3e-23 82.3 0.1 5.3e-14 51.8 0.2 2.5 1 1 1 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 CCU97477.1 - 0.00096 17.9 0.0 0.0016 17.1 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit DPBB_1 PF03330.13 CCU97478.1 - 7.4e-05 22.6 0.1 0.00015 21.6 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel HhH-GPD PF00730.20 CCU97479.1 - 4.6e-20 71.9 0.0 1.3e-19 70.5 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 CCU97479.1 - 3.7e-14 52.1 0.0 9.7e-14 50.7 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.18 CCU97479.1 - 0.0019 17.7 0.1 0.006 16.2 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 CCU97479.1 - 0.0024 17.9 6.3 0.0024 17.9 4.4 2.7 3 0 0 3 3 3 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.1 CCU97479.1 - 0.0028 17.8 0.0 0.14 12.3 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain TPR_2 PF07719.12 CCU97480.1 - 3.1e-35 117.2 21.7 0.00011 21.8 0.0 11.2 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_1 PF00515.23 CCU97480.1 - 3.5e-26 89.6 11.2 0.00083 18.8 0.0 10.1 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 CCU97480.1 - 2.7e-25 87.8 30.9 3.3e-11 42.6 0.2 8.8 6 2 1 8 8 8 6 TPR repeat Apc3 PF12895.2 CCU97480.1 - 1.2e-19 70.2 15.2 2.5e-09 37.1 0.2 6.6 6 1 2 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CCU97480.1 - 2.6e-16 59.3 9.4 2.3e-08 33.8 0.5 8.5 6 2 2 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 CCU97480.1 - 3.2e-16 59.4 59.0 1.4e-11 44.7 0.8 9.6 7 2 0 10 10 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCU97480.1 - 1.4e-15 55.7 0.1 0.0078 15.9 0.0 8.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCU97480.1 - 6.2e-14 52.0 25.0 0.061 13.6 0.8 7.9 5 2 2 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 CCU97480.1 - 1.1e-10 40.4 14.9 0.0032 17.1 0.1 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCU97480.1 - 2.6e-10 39.6 9.9 0.74 10.1 0.0 9.4 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCU97480.1 - 1.1e-08 34.9 54.7 0.026 15.1 0.5 11.2 8 3 4 12 12 10 5 Tetratricopeptide repeat TPR_6 PF13174.1 CCU97480.1 - 3.4e-06 27.1 28.3 0.12 12.8 0.0 9.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.1 CCU97480.1 - 0.00047 19.9 34.1 0.16 11.9 0.1 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCU97480.1 - 0.0059 16.4 35.1 0.019 14.8 0.3 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat PPR PF01535.15 CCU97480.1 - 0.035 14.0 1.1 27 5.0 0.0 4.3 6 0 0 6 6 4 0 PPR repeat Fes1 PF08609.5 CCU97481.1 - 2.1e-20 72.9 0.9 7.4e-20 71.2 0.2 2.2 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 Arm PF00514.18 CCU97481.1 - 0.0001 21.9 1.1 0.51 10.2 0.2 3.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CCU97481.1 - 0.00088 19.5 8.4 0.0058 16.8 1.9 3.0 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 CCU97481.1 - 0.0075 16.7 1.3 0.0075 16.7 0.9 4.0 5 1 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.15 CCU97481.1 - 0.06 11.6 0.1 1.1 7.4 0.0 2.1 1 1 1 2 2 2 0 Adaptin N terminal region HEAT PF02985.17 CCU97481.1 - 0.11 12.6 1.1 46 4.4 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat PTS_2-RNA PF01885.11 CCU97481.1 - 0.12 11.6 0.1 0.35 10.1 0.0 1.7 2 0 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family FAM165 PF14981.1 CCU97482.1 - 0.14 11.6 0.9 0.2 11.1 0.6 1.2 1 0 0 1 1 1 0 FAM165 family Pkinase PF00069.20 CCU97483.1 - 1.3e-36 126.1 0.0 1.7e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97483.1 - 3.9e-19 68.7 0.0 1.4e-18 66.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU97483.1 - 0.00032 19.7 0.1 0.031 13.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.6 CCU97483.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 XRCC4 PF06632.7 CCU97483.1 - 1.9 7.2 3.9 3 6.6 2.7 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Cullin PF00888.17 CCU97484.1 - 1.1e-131 440.2 0.0 3e-131 438.8 0.0 1.6 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CCU97484.1 - 2.3e-24 84.9 0.2 6.2e-24 83.6 0.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Fork_head PF00250.13 CCU97485.1 - 2.5e-29 101.1 0.0 5.3e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Fork head domain Aminotran_3 PF00202.16 CCU97486.1 - 2.6e-101 338.8 0.0 3.1e-101 338.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CCU97486.1 - 0.001 18.0 0.0 0.0023 16.9 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCU97486.1 - 0.088 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase CPSase_L_D2 PF02786.12 CCU97487.1 - 3e-79 265.1 0.0 5.3e-79 264.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CCU97487.1 - 2.9e-62 209.5 0.0 5.3e-62 208.7 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CCU97487.1 - 6.3e-36 122.8 0.6 1.7e-35 121.4 0.1 2.1 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCU97487.1 - 2.6e-28 98.1 0.0 7.1e-28 96.7 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 CCU97487.1 - 4.6e-27 95.2 0.0 8.2e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 CCU97487.1 - 1.1e-17 64.3 0.1 2.1e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCU97487.1 - 6.5e-16 57.9 0.0 1.9e-15 56.4 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 CCU97487.1 - 4.6e-15 55.0 1.6 1.1e-14 53.7 0.8 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CCU97487.1 - 1.2e-09 37.6 1.1 4.9e-06 26.1 0.2 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 CCU97487.1 - 1.4e-08 34.3 0.0 2.7e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CCU97487.1 - 3.1e-05 23.4 0.0 6.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CCU97487.1 - 0.0002 20.9 0.0 0.0025 17.3 0.0 2.3 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CCU97487.1 - 0.0014 18.5 0.0 0.004 17.0 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 CCU97487.1 - 0.0038 17.5 0.1 0.2 12.0 0.0 2.5 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 CCU97487.1 - 0.0097 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.6 CCU97487.1 - 0.03 13.5 0.4 0.059 12.5 0.3 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD PF00529.15 CCU97487.1 - 0.031 13.5 0.9 0.089 12.0 0.1 2.1 2 1 1 3 3 3 0 HlyD family secretion protein GCV_H PF01597.14 CCU97487.1 - 0.15 11.7 0.7 0.45 10.1 0.2 1.9 2 0 0 2 2 1 0 Glycine cleavage H-protein Ribosomal_S13 PF00416.17 CCU97488.1 - 8.7e-40 135.4 1.2 1e-39 135.2 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CCU97488.1 - 0.00053 18.6 0.0 0.00061 18.4 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 CCU97488.1 - 0.0076 16.2 0.5 0.024 14.6 0.1 1.9 2 1 0 2 2 2 1 Helix-hairpin-helix motif DUF1822 PF08852.6 CCU97488.1 - 0.025 13.3 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Mito_carr PF00153.22 CCU97489.1 - 1.7e-71 235.9 2.6 7.1e-24 83.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein eIF3g PF12353.3 CCU97491.1 - 9.1e-40 135.5 1.2 1.3e-39 135.0 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 CCU97491.1 - 1.4e-18 66.2 0.0 2.3e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU97491.1 - 2.8e-15 56.0 0.0 7e-15 54.7 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU97491.1 - 2.3e-09 36.9 0.0 4.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2782 PF11191.3 CCU97491.1 - 0.89 9.5 0.0 0.89 9.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2782) vATP-synt_E PF01991.13 CCU97492.1 - 2.1e-50 170.7 13.2 2.7e-50 170.4 9.1 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2333 PF10095.4 CCU97492.1 - 0.067 11.8 0.8 0.094 11.3 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) UPF0449 PF15136.1 CCU97492.1 - 0.11 12.6 4.5 0.21 11.8 2.6 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF2762 PF10960.3 CCU97492.1 - 0.41 10.3 4.7 0.14 11.9 1.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2762) Phlebovirus_NSM PF07246.6 CCU97492.1 - 3.1 6.8 8.6 4.7 6.2 6.0 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M V_ATPase_I PF01496.14 CCU97492.1 - 3.3 5.4 7.3 4.1 5.1 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L37 PF08561.5 CCU97493.1 - 1.9e-24 85.0 4.7 1.8e-22 78.6 3.2 2.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 Selenoprotein_S PF06936.6 CCU97493.1 - 0.07 12.6 7.6 0.094 12.2 5.2 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) RabGAP-TBC PF00566.13 CCU97494.1 - 2.3e-48 164.5 0.0 3.4e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CPSF73-100_C PF11718.3 CCU97495.1 - 3.5e-46 157.2 0.0 6.4e-46 156.4 0.0 1.4 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CCU97495.1 - 1.4e-31 109.0 0.0 2.5e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 CCU97495.1 - 4.9e-11 42.2 0.1 9.7e-11 41.3 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 CCU97495.1 - 0.0002 20.9 0.0 0.00089 18.8 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain MCM PF00493.18 CCU97496.1 - 7.9e-136 452.1 0.0 1.1e-135 451.7 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCU97496.1 - 1.9e-18 67.1 0.1 7.9e-18 65.0 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 CCU97496.1 - 4.9e-08 32.7 0.1 2.2e-07 30.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CCU97496.1 - 2.6e-07 30.0 0.0 7.3e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCU97496.1 - 4.5e-05 23.0 0.0 0.0009 18.8 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCU97496.1 - 0.0014 18.1 0.1 2.9 7.3 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_32 PF13654.1 CCU97496.1 - 0.051 12.2 0.8 0.13 10.8 0.4 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CCU97496.1 - 0.15 12.0 11.1 2.3 8.1 0.6 4.6 2 1 1 3 3 3 0 AAA ATPase domain HORMA PF02301.13 CCU97497.1 - 2.5e-41 141.4 0.0 2.9e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 HORMA domain DUF1649 PF07855.7 CCU97497.1 - 0.076 12.6 0.1 0.31 10.7 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1649) Y_phosphatase2 PF03162.8 CCU97498.1 - 7.2e-59 197.8 0.0 9.1e-59 197.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCU97498.1 - 2e-07 31.4 0.0 3.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CCU97498.1 - 0.00098 18.5 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CCU97498.1 - 0.0014 18.1 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ATP-synt_G PF04718.10 CCU97499.1 - 8.5e-14 52.0 2.0 1.8e-13 50.9 1.1 1.8 1 1 0 1 1 1 1 Mitochondrial ATP synthase g subunit Misat_Tub_SegII PF10644.4 CCU97501.1 - 1.2e-17 64.0 0.0 2.1e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CCU97501.1 - 3.4e-17 62.5 0.0 9.2e-17 61.0 0.0 1.7 1 1 0 1 1 1 1 Tubulin domain Pterin_4a PF01329.14 CCU97501.1 - 2.4e-15 56.0 0.6 4.8e-15 55.0 0.0 1.7 2 0 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase DUF2781 PF10914.3 CCU97501.1 - 2.1e-07 30.8 2.0 8.7e-07 28.8 1.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) Tubulin PF00091.20 CCU97501.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Vps16_C PF04840.7 CCU97502.1 - 2.5e-44 151.5 0.0 3.1e-25 88.7 0.0 2.1 2 0 0 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.8 CCU97502.1 - 6.3e-41 140.2 0.0 1.2e-23 83.3 0.0 2.2 2 0 0 2 2 2 2 Vps16, N-terminal region GCS PF03074.11 CCU97503.1 - 1.7e-122 409.0 0.0 3e-122 408.2 0.0 1.3 1 1 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.8 CCU97503.1 - 0.0051 15.9 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) UCH PF00443.24 CCU97504.1 - 1.5e-05 24.2 0.0 1.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UMP1 PF05348.6 CCU97505.1 - 1.2e-24 86.7 1.0 1.4e-24 86.5 0.7 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 rRNA_proc-arch PF13234.1 CCU97506.1 - 1.3e-84 283.4 0.0 1.9e-84 283.0 0.0 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 CCU97506.1 - 7.1e-58 194.8 0.4 1.3e-57 193.9 0.2 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CCU97506.1 - 1.5e-21 76.5 0.0 3.4e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU97506.1 - 5.6e-06 26.1 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCU97506.1 - 0.022 14.5 0.0 0.15 11.8 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit HAMP PF00672.20 CCU97506.1 - 0.047 13.8 1.6 4.9 7.3 0.1 2.6 2 0 0 2 2 2 0 HAMP domain KaiC PF06745.8 CCU97506.1 - 0.078 12.0 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 KaiC NMD3 PF04981.8 CCU97507.1 - 1.4e-76 256.6 3.8 2e-76 256.2 2.6 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 CCU97507.1 - 0.0015 18.2 4.1 0.012 15.3 2.0 2.6 2 1 0 2 2 2 1 Double zinc ribbon GcpE PF04551.9 CCU97507.1 - 0.084 11.6 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 GcpE protein NinF PF05810.7 CCU97507.1 - 0.48 10.2 4.6 0.85 9.4 0.3 3.0 3 1 0 3 3 3 0 NinF protein zf-C4pol PF14260.1 CCU97507.1 - 1.9 8.5 4.6 1.5 8.8 1.1 2.4 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta TFIIE_alpha PF02002.12 CCU97508.1 - 1.4e-12 47.0 0.0 2.5e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit Bul1_N PF04425.7 CCU97508.1 - 0.1 11.1 0.9 0.15 10.5 0.6 1.2 1 0 0 1 1 1 0 Bul1 N terminus MFS_1 PF07690.11 CCU97509.1 - 4.6e-19 68.3 34.5 9.3e-18 64.0 9.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily ThiF PF00899.16 CCU97510.1 - 1.5e-42 144.5 0.1 3.3e-42 143.5 0.1 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CCU97510.1 - 1.8e-29 101.1 0.4 9.4e-29 98.7 0.1 2.2 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCU97510.1 - 3e-20 71.3 5.6 5.7e-20 70.4 3.9 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 CCU97510.1 - 3.7e-10 39.7 0.2 7.2e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 CCU97510.1 - 0.0046 17.0 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CCU97510.1 - 0.013 15.8 1.0 0.32 11.4 0.1 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.18 CCU97510.1 - 0.053 13.3 0.3 3.7 7.3 0.1 2.5 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CCU97510.1 - 0.096 12.9 0.5 0.62 10.3 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding PAPA-1 PF04795.7 CCU97511.1 - 1.1e-18 67.6 0.9 1.1e-18 67.6 0.7 2.6 2 1 0 2 2 2 1 PAPA-1-like conserved region YL1 PF05764.8 CCU97511.1 - 9.8 5.7 31.5 4.7 6.7 7.2 2.2 1 1 1 2 2 2 0 YL1 nuclear protein HA2 PF04408.18 CCU97512.1 - 4e-27 94.1 1.6 5e-27 93.9 0.1 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCU97512.1 - 6.4e-21 74.3 0.0 1.3e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCU97512.1 - 3.1e-11 42.9 0.0 9.6e-11 41.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 CCU97512.1 - 3.8e-10 39.7 0.9 8.2e-10 38.6 0.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain T2SE PF00437.15 CCU97512.1 - 0.00012 21.1 0.0 0.00038 19.4 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein DEAD PF00270.24 CCU97512.1 - 0.00024 20.6 0.1 0.00051 19.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCU97512.1 - 0.00027 21.0 0.2 0.001 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCU97512.1 - 0.005 16.5 0.2 0.021 14.5 0.2 2.1 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 CCU97512.1 - 0.0065 16.7 0.1 0.21 11.8 0.1 2.5 1 1 0 1 1 1 1 ABC transporter Sigma54_activ_2 PF14532.1 CCU97512.1 - 0.026 14.5 0.0 0.082 12.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Miro PF08477.8 CCU97512.1 - 0.052 14.0 0.1 0.17 12.3 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein UPF0079 PF02367.12 CCU97512.1 - 0.055 13.0 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 CCU97512.1 - 0.11 12.3 0.0 1 9.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.17 CCU97512.1 - 0.11 11.8 0.4 0.54 9.6 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 CCU97512.1 - 0.21 10.3 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain GATA PF00320.22 CCU97513.1 - 0.00094 18.4 7.4 0.014 14.7 0.1 2.6 2 0 0 2 2 2 2 GATA zinc finger Sel1 PF08238.7 CCU97514.1 - 1e-42 143.5 14.0 9.6e-07 29.2 0.1 7.3 7 0 0 7 7 7 7 Sel1 repeat TPR_14 PF13428.1 CCU97514.1 - 0.17 12.6 11.1 0.75 10.6 0.6 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat EF-hand_1 PF00036.27 CCU97515.1 - 2.9e-36 119.9 11.0 1.5e-10 39.6 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CCU97515.1 - 1.1e-34 117.8 7.3 4.1e-17 61.5 0.3 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 CCU97515.1 - 4.6e-34 116.3 2.9 4e-21 74.9 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCU97515.1 - 6.1e-27 91.0 4.3 3.4e-09 35.8 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CCU97515.1 - 4.9e-26 88.8 5.8 1.7e-07 30.2 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CCU97515.1 - 3e-13 49.4 0.2 2e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CCU97515.1 - 2.2e-09 36.9 0.3 0.00012 21.7 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 CCU97515.1 - 6.8e-09 35.2 1.0 0.0093 15.5 0.0 3.9 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 CCU97515.1 - 2.3e-08 34.0 0.0 0.0011 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 CCU97515.1 - 7.7e-06 25.7 0.5 1.7e-05 24.6 0.2 1.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 CCU97515.1 - 0.00023 20.6 1.3 0.00027 20.4 0.9 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.8 CCU97515.1 - 0.00026 20.7 0.2 0.5 10.0 0.0 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TerB EF-hand_like PF09279.6 CCU97515.1 - 0.00039 20.3 0.1 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like RNA_pol_Rpb4 PF03874.11 CCU97515.1 - 0.013 15.5 1.1 1.5 8.8 0.1 2.4 3 0 0 3 3 2 0 RNA polymerase Rpb4 LNS2 PF08235.8 CCU97515.1 - 0.028 13.9 0.1 0.35 10.4 0.0 2.0 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DUF3349 PF11829.3 CCU97515.1 - 0.042 14.2 0.3 9.1 6.7 0.0 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) Tenui_NCP PF04876.7 CCU97515.1 - 0.079 12.4 0.1 2.3 7.7 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein PB1 PF00564.19 CCU97515.1 - 0.14 11.8 1.8 46 3.7 0.0 3.6 2 2 2 4 4 4 0 PB1 domain DUF533 PF04391.7 CCU97515.1 - 0.23 10.7 1.4 21 4.4 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF533) DUF3018 PF11455.3 CCU97515.1 - 0.24 11.3 1.3 27 4.7 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3018) KIP1 PF07765.7 CCU97515.1 - 0.31 10.9 1.0 11 5.9 0.0 2.8 2 1 1 3 3 3 0 KIP1-like protein GTSE1_N PF15259.1 CCU97516.1 - 0.0065 16.4 5.7 0.0065 16.4 3.9 2.3 2 1 0 2 2 2 1 G-2 and S-phase expressed 1 PP_M1 PF03012.9 CCU97516.1 - 6.1 6.1 10.2 0.067 12.5 0.9 2.0 2 0 0 2 2 2 0 Phosphoprotein Mitofilin PF09731.4 CCU97516.1 - 9.3 4.7 33.1 4.4 5.8 12.7 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Maf1 PF09174.5 CCU97517.1 - 5.2e-35 120.9 0.0 4.6e-29 101.5 0.0 2.2 2 0 0 2 2 2 2 Maf1 regulator Peptidase_S10 PF00450.17 CCU97518.1 - 8.7e-91 305.1 0.0 1.2e-90 304.6 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Histidinol_dh PF00815.15 CCU97519.1 - 4.5e-167 555.8 0.8 1.6e-166 554.0 0.6 1.8 1 1 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 CCU97519.1 - 6.2e-24 83.4 0.5 1.2e-23 82.5 0.4 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 CCU97519.1 - 5e-11 42.7 0.4 2.7e-10 40.3 0.1 2.3 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 CCU97519.1 - 0.03 14.2 0.1 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain UPF0047 PF01894.12 CCU97520.1 - 8.3e-42 141.7 0.0 9.4e-42 141.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Carn_acyltransf PF00755.15 CCU97521.1 - 5.2e-130 434.3 0.0 1.2e-129 433.1 0.0 1.5 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF2359 PF10151.4 CCU97521.1 - 0.04 12.4 0.1 0.055 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) Pkinase PF00069.20 CCU97522.1 - 5e-56 189.7 0.0 6.5e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97522.1 - 7.9e-29 100.4 0.0 1.4e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU97522.1 - 1.5e-07 30.6 0.0 3.8e-07 29.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCU97522.1 - 0.00013 21.8 5.6 0.2 11.3 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 CCU97522.1 - 0.002 17.2 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MKT1_C PF12246.3 CCU97523.1 - 2.1e-64 216.8 0.0 3.2e-64 216.2 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 CCU97523.1 - 1.4e-22 79.8 0.0 2.8e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 CCU97523.1 - 2.3e-06 27.5 0.0 4.9e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CCU97523.1 - 6.2e-05 23.1 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain SARA PF11409.3 CCU97523.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) Ribosomal_L5_C PF00673.16 CCU97524.1 - 1.6e-23 82.2 0.0 2.4e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CCU97524.1 - 2.8e-19 68.6 0.3 2.5e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 Tis11B_N PF04553.7 CCU97524.1 - 0.29 11.3 1.5 0.49 10.5 0.0 2.0 2 1 1 3 3 3 0 Tis11B like protein, N terminus DEAD PF00270.24 CCU97526.1 - 6.2e-44 149.4 0.0 8.5e-43 145.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU97526.1 - 7.9e-27 92.9 0.0 1.6e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCU97526.1 - 0.0073 16.1 0.0 0.021 14.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IU_nuc_hydro PF01156.14 CCU97527.1 - 1.6e-47 162.2 0.0 2.4e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.17 CCU97528.1 - 1.9e-18 65.7 0.5 3.4e-18 64.9 0.4 1.4 1 1 0 1 1 1 1 LSM domain PBP1_TM PF14812.1 CCU97528.1 - 0.14 12.4 1.4 0.22 11.8 1.0 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aminotran_1_2 PF00155.16 CCU97529.1 - 1.4e-26 93.3 0.0 1.8e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CCU97529.1 - 1.2e-07 30.6 0.0 1.8e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Dyp_perox PF04261.7 CCU97529.1 - 0.14 10.8 0.0 0.31 9.7 0.0 1.5 1 0 0 1 1 1 0 Dyp-type peroxidase family Sec1 PF00995.18 CCU97530.1 - 3.3e-96 323.1 0.0 7.9e-96 321.9 0.0 1.5 1 1 0 1 1 1 1 Sec1 family VWA_2 PF13519.1 CCU97530.1 - 0.0023 18.0 0.5 0.051 13.6 0.1 2.8 3 0 0 3 3 3 1 von Willebrand factor type A domain PAT1 PF09770.4 CCU97531.1 - 2.4e-152 509.0 17.4 3.4e-134 449.0 0.6 2.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 PTCB-BRCT PF12738.2 CCU97532.1 - 1.7e-28 98.2 4.2 4e-15 55.4 0.0 4.5 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 CCU97532.1 - 3.6e-24 84.7 0.0 9.3e-09 35.3 0.0 5.3 5 0 0 5 5 5 5 BRCA1 C Terminus (BRCT) domain Sulfate_transp PF00916.15 CCU97533.1 - 6.6e-79 264.8 5.2 1.3e-78 263.8 3.6 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CCU97533.1 - 1.1e-29 101.9 4.2 1.1e-29 101.9 2.9 3.5 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CCU97533.1 - 2.3e-09 36.6 0.0 1.2e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.1 CCU97533.1 - 0.0017 18.3 0.1 0.005 16.8 0.0 1.7 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 CCU97533.1 - 0.012 15.3 1.7 0.069 12.8 1.2 2.4 1 0 0 1 1 1 0 Stannin transmembrane CNH PF00780.17 CCU97534.1 - 4.6e-38 131.2 0.0 6.7e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 CCU97534.1 - 6.7e-24 84.7 0.0 1e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain CDP-OH_P_transf PF01066.16 CCU97535.1 - 2.4e-15 56.6 4.6 2.4e-15 56.6 3.2 2.8 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Cnd2 PF05786.9 CCU97536.1 - 1.1e-134 450.6 6.2 1.4e-79 268.4 0.3 2.9 1 1 1 2 2 2 2 Condensin complex subunit 2 DUF416 PF04222.7 CCU97536.1 - 0.038 13.1 0.1 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF416) DAGAT PF03982.8 CCU97537.1 - 3.1e-73 246.0 0.1 4.7e-73 245.4 0.1 1.3 1 1 0 1 1 1 1 Diacylglycerol acyltransferase PLA2_B PF01735.13 CCU97539.1 - 2e-143 478.1 0.2 2.4e-143 477.8 0.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.17 CCU97539.1 - 0.019 14.9 0.3 0.064 13.1 0.0 2.0 2 0 0 2 2 2 0 Patatin-like phospholipase GTP_EFTU PF00009.22 CCU97540.1 - 9e-46 155.6 0.0 1.3e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 CCU97540.1 - 1.7e-34 117.9 0.1 3.2e-34 117.0 0.1 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 CCU97540.1 - 9.4e-16 57.4 0.0 1.7e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCU97540.1 - 1e-06 28.7 0.1 1.9e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CCU97540.1 - 7.6e-06 25.6 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 CCU97540.1 - 0.00023 21.0 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCU97540.1 - 0.011 14.9 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit WD40 PF00400.27 CCU97541.1 - 8.5e-26 88.8 3.1 7.2e-08 32.0 0.3 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCU97541.1 - 0.006 16.0 0.0 0.026 14.0 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain MMS1_N PF10433.4 CCU97541.1 - 0.16 10.0 0.0 0.25 9.4 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Aminotran_1_2 PF00155.16 CCU97543.1 - 1.8e-47 162.0 0.0 2.3e-46 158.3 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCU97543.1 - 0.0024 17.0 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 CCU97543.1 - 0.031 12.8 0.0 0.067 11.7 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aldedh PF00171.17 CCU97544.1 - 3.3e-122 408.1 0.1 7.2e-122 407.0 0.0 1.5 2 0 0 2 2 2 1 Aldehyde dehydrogenase family JAB PF01398.16 CCU97545.1 - 1.5e-26 92.3 0.0 2.4e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CCU97545.1 - 1.7e-07 30.7 0.0 4.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CCU97545.1 - 0.061 12.8 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Cyclin_N PF00134.18 CCU97546.1 - 1.5e-43 147.3 0.1 7.5e-41 138.6 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCU97546.1 - 8.1e-31 106.3 0.1 1.3e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Yippee-Mis18 PF03226.9 CCU97547.1 - 3.5e-21 75.0 0.0 5.3e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AT_hook PF02178.14 CCU97547.1 - 0.0053 16.2 9.6 0.029 14.0 1.8 3.0 2 0 0 2 2 2 2 AT hook motif DUF2457 PF10446.4 CCU97547.1 - 0.033 12.9 1.1 0.052 12.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Phlebovirus_G1 PF07243.6 CCU97547.1 - 0.25 9.4 1.3 0.35 8.9 0.9 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 DCP1 PF06058.8 CCU97548.1 - 2.4e-23 82.5 0.0 3.8e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family TIMELESS PF04821.9 CCU97549.1 - 1.2e-41 142.7 0.0 1.8e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Timeless protein DEAD PF00270.24 CCU97550.1 - 4.2e-33 114.2 0.2 7e-32 110.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU97550.1 - 1.3e-25 89.0 0.3 2.4e-25 88.1 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CCU97550.1 - 0.0021 18.0 0.0 0.005 16.8 0.0 1.7 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_30 PF13604.1 CCU97550.1 - 0.021 14.3 0.0 0.085 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain SPA PF08616.5 CCU97551.1 - 1.8e-05 24.3 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CCU97551.1 - 0.00057 18.4 0.0 0.0027 16.2 0.0 1.9 1 1 0 1 1 1 1 Transport protein Avl9 DENN PF02141.16 CCU97551.1 - 0.00067 19.4 0.0 0.0098 15.6 0.0 2.3 1 1 0 1 1 1 1 DENN (AEX-3) domain Afi1 PF07792.7 CCU97551.1 - 0.14 12.1 0.0 0.72 9.8 0.0 1.9 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CRAL_TRIO PF00650.15 CCU97552.1 - 2.1e-23 82.5 0.0 3.5e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CCU97552.1 - 0.00077 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Ribosomal_L32e PF01655.13 CCU97553.1 - 2.3e-40 137.0 1.2 5.9e-40 135.7 0.9 1.7 1 1 0 1 1 1 1 Ribosomal protein L32 DUF3301 PF11743.3 CCU97553.1 - 0.055 13.0 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Ribosomal_L13 PF00572.13 CCU97554.1 - 5.8e-26 91.0 0.0 8.5e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 TctB PF07331.6 CCU97555.1 - 0.00022 20.8 2.3 0.0031 17.1 1.5 2.2 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family Mg_trans_NIPA PF05653.9 CCU97555.1 - 0.00087 18.3 1.2 0.15 10.9 0.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Stm1_N PF09598.5 CCU97556.1 - 0.0001 22.8 2.6 0.0001 22.8 1.8 4.6 2 1 0 2 2 2 1 Stm1 HABP4_PAI-RBP1 PF04774.10 CCU97556.1 - 0.0005 20.5 15.2 0.0005 20.5 10.5 3.4 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Vfa1 PF08432.5 CCU97556.1 - 1.7 8.6 7.1 2.5 8.0 4.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Caprin-1_C PF12287.3 CCU97556.1 - 6.5 6.0 15.5 0.11 11.9 3.8 2.3 2 0 0 2 2 2 0 Cytoplasmic activation/proliferation-associated protein-1 C term Ribosomal_S3_C PF00189.15 CCU97557.1 - 2.8e-16 59.4 0.1 4.6e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CCU97557.1 - 1.1e-10 40.8 0.0 2.2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 KH domain Dynamin_N PF00350.18 CCU97558.1 - 2e-39 135.1 0.0 3.9e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 CCU97558.1 - 2.8e-06 26.3 0.1 1.7e-05 23.7 0.0 2.3 3 0 0 3 3 3 1 Dynamin central region Miro PF08477.8 CCU97558.1 - 0.0023 18.3 0.1 0.0076 16.7 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCU97558.1 - 0.0044 16.9 0.0 0.015 15.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNase_T PF00929.19 CCU97559.1 - 6.1e-17 62.3 0.0 1.1e-16 61.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Y_phosphatase3 PF13350.1 CCU97559.1 - 0.014 15.6 0.2 0.027 14.7 0.2 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PP2C PF00481.16 CCU97560.1 - 2.6e-30 105.6 0.0 4e-19 69.0 0.0 3.2 3 0 0 3 3 3 3 Protein phosphatase 2C SAC3_GANP PF03399.11 CCU97560.1 - 2.8e-29 102.1 0.0 4.5e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CCU97560.1 - 7.1e-28 97.1 0.0 1.2e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 AAA PF00004.24 CCU97561.1 - 7.7e-52 174.9 0.0 3.4e-39 134.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 CCU97561.1 - 1.5e-09 37.3 0.4 6.6e-08 32.0 0.1 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 CCU97561.1 - 4.5e-09 36.5 0.1 0.00056 20.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.9 CCU97561.1 - 1.1e-08 35.1 0.0 1.1e-05 25.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 CCU97561.1 - 1.5e-07 30.4 0.0 0.013 14.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 CCU97561.1 - 1.6e-07 31.5 0.1 0.0065 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CCU97561.1 - 4e-07 29.8 0.2 0.0012 18.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CCU97561.1 - 8.5e-07 28.9 0.0 0.039 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CCU97561.1 - 1.5e-06 27.8 1.3 0.055 13.2 0.0 3.0 3 0 0 3 3 2 2 Part of AAA domain RuvB_N PF05496.7 CCU97561.1 - 2.1e-06 27.0 0.2 0.015 14.3 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CCU97561.1 - 3e-06 28.0 0.0 0.0091 16.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCU97561.1 - 5.9e-06 25.5 0.3 0.0042 16.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CCU97561.1 - 8.9e-06 25.4 1.0 0.018 14.7 0.0 3.3 3 1 0 3 3 3 2 NACHT domain IstB_IS21 PF01695.12 CCU97561.1 - 1e-05 25.0 0.3 0.035 13.5 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_33 PF13671.1 CCU97561.1 - 1.2e-05 25.2 0.0 0.085 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CCU97561.1 - 1.6e-05 25.0 0.0 0.048 13.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 CCU97561.1 - 2.9e-05 24.3 0.3 0.018 15.3 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.1 CCU97561.1 - 3.5e-05 23.2 0.6 0.19 11.1 0.0 3.3 2 1 0 3 3 3 2 AAA domain PhoH PF02562.11 CCU97561.1 - 3.5e-05 23.1 0.0 0.054 12.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.1 CCU97561.1 - 5.6e-05 22.7 0.1 0.37 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 CCU97561.1 - 0.00011 21.9 2.4 0.044 13.3 0.1 2.7 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CCU97561.1 - 0.00011 21.6 0.1 0.6 9.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 CCU97561.1 - 0.00016 20.8 0.2 0.0055 15.8 0.0 2.5 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.12 CCU97561.1 - 0.00034 19.5 0.1 0.67 8.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 CCU97561.1 - 0.00044 20.5 0.3 0.33 11.2 0.1 2.6 2 0 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 CCU97561.1 - 0.00067 19.4 0.2 7.2 6.2 0.0 3.5 2 2 1 3 3 3 0 Archaeal ATPase UPF0079 PF02367.12 CCU97561.1 - 0.0012 18.5 0.1 0.54 9.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 CCU97561.1 - 0.0012 18.9 0.1 2.8 8.0 0.1 3.5 3 1 0 3 3 2 1 Sigma-54 interaction domain NB-ARC PF00931.17 CCU97561.1 - 0.0013 17.6 0.1 1.1 8.0 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.7 CCU97561.1 - 0.0016 17.5 0.2 0.83 8.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin CDC48_N PF02359.13 CCU97561.1 - 0.0021 17.9 0.0 0.006 16.5 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain DUF2075 PF09848.4 CCU97561.1 - 0.003 16.6 0.1 0.56 9.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 CCU97561.1 - 0.0032 17.0 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CCU97561.1 - 0.0062 16.5 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CCU97561.1 - 0.0066 16.0 0.0 0.09 12.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CCU97561.1 - 0.0068 16.2 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 CCU97561.1 - 0.023 13.6 0.0 3.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DAP3 PF10236.4 CCU97561.1 - 0.024 13.5 0.0 1.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 CCU97561.1 - 0.051 13.1 0.3 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.4 CCU97561.1 - 0.13 10.8 0.2 3.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain KTI12 PF08433.5 CCU97561.1 - 0.24 10.5 0.1 0.61 9.2 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 VID27 PF08553.5 CCU97562.1 - 8.7e-251 834.5 0.2 4.8e-250 832.0 0.1 1.9 1 1 0 1 1 1 1 VID27 cytoplasmic protein eIF-3_zeta PF05091.7 CCU97563.1 - 2.6e-166 554.2 0.0 3.1e-166 554.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4110 PF13422.1 CCU97564.1 - 2.9 7.7 11.2 10 6.0 7.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4110) APH PF01636.18 CCU97565.1 - 1.3e-10 41.4 0.5 3.6e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 CCU97565.1 - 1.3e-08 34.3 0.0 1.5e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 CCU97565.1 - 1.7e-08 33.7 0.0 1.2e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCU97565.1 - 3.5e-08 33.0 0.0 8.6e-08 31.7 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 CCU97565.1 - 0.0003 19.9 0.0 0.00032 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.15 CCU97565.1 - 0.0032 16.6 0.0 0.0059 15.7 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 CCU97565.1 - 0.026 14.0 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 CCU97566.1 - 2.9e-30 105.2 0.0 7.4e-18 64.6 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97566.1 - 6.5e-07 28.6 0.0 0.0007 18.7 0.0 3.3 2 1 0 2 2 2 1 Protein tyrosine kinase Peptidase_M24 PF00557.19 CCU97568.1 - 3e-41 141.2 0.0 5e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CCU97568.1 - 6.7e-20 71.9 0.0 1.4e-15 57.9 0.0 2.5 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain AMP_N PF05195.11 CCU97568.1 - 0.036 13.4 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain fn3 PF00041.16 CCU97570.1 - 2.7e-05 24.1 0.2 5.9e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain BRCT PF00533.21 CCU97570.1 - 4.7e-05 23.4 0.0 8.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCU97570.1 - 7.3e-05 22.5 0.1 0.00013 21.7 0.1 1.4 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.3 CCU97570.1 - 0.0009 18.9 0.0 0.0029 17.2 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) RhoGEF PF00621.15 CCU97571.1 - 3.3e-16 59.6 0.4 3.3e-16 59.6 0.2 1.7 2 0 0 2 2 2 1 RhoGEF domain DUF1640 PF07798.6 CCU97571.1 - 0.15 12.0 1.1 0.28 11.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TSC22 PF01166.13 CCU97571.1 - 0.85 9.6 6.6 4.2 7.4 1.1 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family IncA PF04156.9 CCU97571.1 - 2.7 7.5 5.3 6.2 6.3 3.7 1.7 1 0 0 1 1 1 0 IncA protein DUF500 PF04366.7 CCU97572.1 - 8.3e-30 102.8 0.0 1.2e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF500) ERCC4 PF02732.10 CCU97573.1 - 7.5e-25 87.3 0.1 2.2e-24 85.8 0.0 1.8 2 0 0 2 2 2 1 ERCC4 domain Peptidase_M17 PF00883.16 CCU97574.1 - 6.2e-112 373.4 0.0 7.9e-112 373.1 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CCU97574.1 - 5.8e-08 32.5 0.1 1.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DAO PF01266.19 CCU97575.1 - 2.5e-49 168.1 0.6 3e-49 167.8 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCU97575.1 - 9.5e-09 34.5 0.6 4.2e-07 29.1 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CCU97575.1 - 8.7e-08 32.4 0.2 5.6e-05 23.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCU97575.1 - 2e-05 24.5 0.5 6e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCU97575.1 - 0.0021 17.9 0.1 0.079 12.8 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCU97575.1 - 0.0026 16.8 0.1 0.0056 15.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.13 CCU97575.1 - 0.0067 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Trp_halogenase PF04820.9 CCU97575.1 - 0.0067 15.1 0.3 0.95 8.0 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 CCU97575.1 - 0.011 14.7 0.3 0.16 10.9 0.2 2.0 1 1 0 1 1 1 0 FAD binding domain Mqo PF06039.10 CCU97575.1 - 0.021 13.0 0.0 0.39 8.8 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.7 CCU97575.1 - 0.033 13.1 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 CCU97575.1 - 0.036 13.4 0.0 0.089 12.2 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.14 CCU97575.1 - 0.052 12.7 0.1 1.4 7.9 0.0 2.5 2 1 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.1 CCU97575.1 - 0.069 12.9 0.2 6.7 6.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 CCU97575.1 - 0.075 11.4 0.2 0.46 8.8 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein RRM_6 PF14259.1 CCU97576.1 - 7e-11 41.9 0.0 5e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCU97576.1 - 5.2e-10 38.8 0.0 1.4e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU97576.1 - 0.00016 21.4 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF221 PF02714.10 CCU97578.1 - 1.2e-57 195.2 13.1 2.5e-57 194.1 9.1 1.5 1 1 0 1 1 1 1 Domain of unknown function DUF221 Virul_fac_BrkB PF03631.10 CCU97578.1 - 0.0013 18.1 7.6 0.002 17.5 4.2 1.8 1 1 1 2 2 2 1 Virulence factor BrkB EGF_3 PF12947.2 CCU97579.1 - 1.2 9.1 3.7 0.39 10.7 0.3 1.8 2 0 0 2 2 2 0 EGF domain Glyco_hydro_47 PF01532.15 CCU97581.1 - 1.2e-84 284.5 0.0 1.5e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.15 CCU97582.1 - 5.5e-46 157.1 0.0 6.3e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_transf_20 PF00982.16 CCU97583.1 - 1.5e-132 442.4 5.2 3.1e-131 438.1 3.6 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CCU97583.1 - 6e-71 238.0 0.0 1e-70 237.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase DUF3513 PF12026.3 CCU97583.1 - 0.53 9.7 3.9 2.8 7.4 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) Dor1 PF04124.7 CCU97584.1 - 5.6e-06 25.0 0.3 1.3e-05 23.8 0.1 1.7 2 0 0 2 2 2 1 Dor1-like family SMC_N PF02463.14 CCU97585.1 - 4.7e-31 107.7 1.4 6.9e-31 107.1 1.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCU97585.1 - 2.5e-09 37.1 0.7 1.2e-08 34.9 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain ERM PF00769.14 CCU97585.1 - 8e-05 22.2 15.6 8e-05 22.2 10.8 5.2 3 2 2 5 5 5 1 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 CCU97585.1 - 0.0047 16.1 2.4 0.0047 16.1 1.7 4.2 3 1 1 4 4 4 2 Reovirus sigma C capsid protein AAA_21 PF13304.1 CCU97585.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3533 PF12051.3 CCU97586.1 - 2.9e-71 240.2 9.3 3.5e-71 239.9 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Lipase_3 PF01764.20 CCU97587.1 - 1.3e-17 63.7 0.0 1.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S10 PF00450.17 CCU97588.1 - 1.3e-82 278.2 0.0 1.5e-82 277.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Sel1 PF08238.7 CCU97589.1 - 2.4e-32 110.6 24.2 3.3e-06 27.5 0.0 8.2 9 0 0 9 9 9 6 Sel1 repeat TPR_6 PF13174.1 CCU97589.1 - 0.32 11.5 2.8 1.1 9.8 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Exo_endo_phos PF03372.18 CCU97591.1 - 2.7e-20 73.3 0.1 3.7e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 CCU97591.1 - 4.2e-13 48.5 4.3 7.4e-06 25.4 0.2 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCU97591.1 - 3.9e-09 36.1 1.7 1.8e-05 24.3 0.2 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CCU97591.1 - 2.9e-07 29.5 2.8 0.64 10.2 0.0 4.9 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 CCU97591.1 - 5.4e-05 22.7 5.3 1.4 9.4 0.0 4.6 4 0 0 4 4 4 1 Leucine rich repeat Y_phosphatase PF00102.22 CCU97591.1 - 0.0077 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_6 PF13516.1 CCU97591.1 - 0.43 10.8 3.5 32 5.0 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat HSP90 PF00183.13 CCU97592.1 - 9.7e-252 836.0 30.4 1.2e-251 835.7 21.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CCU97592.1 - 7.9e-12 44.8 0.0 1.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CCU97592.1 - 8.5e-12 44.9 0.2 8.5e-12 44.9 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C37 PF05416.7 CCU97592.1 - 2.3 6.4 10.4 0.15 10.3 0.3 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Bystin PF05291.6 CCU97593.1 - 1.1e-131 438.3 0.0 1.6e-131 437.7 0.0 1.2 1 0 0 1 1 1 1 Bystin BNIP2 PF12496.3 CCU97593.1 - 0.57 10.3 6.7 1.1 9.4 4.7 1.5 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Adaptin_N PF01602.15 CCU97594.1 - 1.9e-83 280.5 0.0 2.8e-83 280.0 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CCU97594.1 - 5.9e-05 23.2 18.0 0.0026 18.0 0.1 5.4 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 CCU97594.1 - 0.0003 20.6 4.3 2.1 8.6 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 CCU97594.1 - 3.6 8.2 17.3 9 6.9 0.2 6.3 4 2 3 7 7 7 0 HEAT-like repeat Phos_pyr_kin PF08543.7 CCU97595.1 - 2.1e-75 253.0 0.4 9.9e-59 198.4 0.1 2.1 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CCU97595.1 - 2.9e-37 128.4 1.0 5.2e-37 127.6 0.7 1.4 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 CCU97595.1 - 0.00024 20.3 0.2 0.0012 18.0 0.0 1.9 2 0 0 2 2 2 1 pfkB family carbohydrate kinase SRP40_C PF05022.7 CCU97596.1 - 1.6e-26 92.5 1.9 1.6e-26 92.5 1.3 2.3 2 0 0 2 2 2 1 SRP40, C-terminal domain Cut8_N PF14482.1 CCU97596.1 - 0.42 10.6 4.6 0.92 9.5 2.8 2.0 1 1 0 1 1 1 0 Cut8 proteasome-binding domain Thiolase_N PF00108.18 CCU97597.1 - 1.5e-79 266.7 0.3 1.9e-79 266.3 0.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCU97597.1 - 4.9e-48 161.6 0.3 1.2e-47 160.3 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCU97597.1 - 7.7e-05 22.2 1.1 0.0002 20.9 0.8 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF4358 PF14270.1 CCU97597.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) SAPS PF04499.10 CCU97598.1 - 1.7e-129 432.5 0.6 2.3e-129 432.1 0.4 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein V_ATPase_I PF01496.14 CCU97598.1 - 0.43 8.3 0.7 0.67 7.7 0.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Malate_synthase PF01274.17 CCU97599.1 - 1.5e-207 689.8 0.0 1.6e-207 689.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Gar1 PF04410.9 CCU97600.1 - 1.2e-33 115.7 0.1 2.4e-33 114.7 0.1 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Tmemb_cc2 PF10267.4 CCU97600.1 - 1.8 7.0 5.6 3.3 6.1 3.9 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein FA_desaturase PF00487.19 CCU97602.1 - 3.8e-24 85.5 25.9 8e-24 84.4 17.9 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DBR1 PF05011.8 CCU97603.1 - 2.9e-19 69.3 0.0 5.7e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 CCU97603.1 - 7.4e-08 32.0 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCU97603.1 - 0.00063 19.5 0.0 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_M16 PF00675.15 CCU97604.1 - 3.7e-43 146.8 1.5 4.1e-41 140.2 0.0 3.7 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCU97604.1 - 3.3e-32 111.6 0.0 6.3e-21 74.8 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Enolase_C PF00113.17 CCU97605.1 - 4.4e-144 478.9 0.3 6.4e-144 478.3 0.2 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CCU97605.1 - 6.3e-57 191.1 0.1 9.9e-57 190.5 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 CCU97605.1 - 5.9e-05 23.0 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 CCU97605.1 - 0.012 14.5 0.6 0.026 13.4 0.1 1.7 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Lactamase_B PF00753.22 CCU97606.1 - 0.00062 19.4 0.3 0.0012 18.5 0.1 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily T2SE_Nter PF05157.10 CCU97606.1 - 0.067 13.2 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain DUF1325 PF07039.6 CCU97607.1 - 6.5e-27 93.7 0.0 1.1e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Rrn6 PF10214.4 CCU97607.1 - 4.2e-06 25.1 0.0 4.2e-06 25.1 0.0 2.7 3 0 0 3 3 3 2 RNA polymerase I-specific transcription-initiation factor PNRC PF15365.1 CCU97607.1 - 6.6e-05 22.8 6.9 0.00011 22.0 3.2 2.8 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator RF-1 PF00472.15 CCU97608.1 - 2.3e-40 136.9 1.9 4.6e-40 135.9 1.3 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CCU97608.1 - 5e-22 77.7 1.5 5.7e-22 77.5 0.1 1.8 2 0 0 2 2 2 1 PCRF domain Vir_act_alpha_C PF10400.4 CCU97608.1 - 0.059 13.7 1.5 0.85 10.0 0.4 2.8 2 1 1 3 3 3 0 Virulence activator alpha C-term Adaptin_N PF01602.15 CCU97609.1 - 8.3e-85 285.0 16.6 1.4e-84 284.3 11.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CCU97609.1 - 1e-59 199.9 0.0 3.9e-59 198.0 0.0 2.1 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CCU97609.1 - 1.5e-59 199.6 0.2 4.5e-59 198.1 0.1 1.9 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CCU97609.1 - 3.1e-13 49.7 12.2 1.5e-05 25.1 0.0 6.0 3 1 3 6 6 6 3 HEAT repeats Cnd1 PF12717.2 CCU97609.1 - 2.8e-07 30.5 10.3 0.024 14.4 0.0 5.3 5 2 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CCU97609.1 - 4.5e-05 23.1 1.9 0.078 13.0 0.0 5.4 6 0 0 6 6 5 1 HEAT repeat HEAT_EZ PF13513.1 CCU97609.1 - 0.00033 21.0 3.0 9.5 6.8 0.0 5.9 4 2 3 7 7 7 1 HEAT-like repeat ParcG PF10274.4 CCU97609.1 - 0.0008 19.3 5.7 0.025 14.4 0.1 3.5 2 1 0 3 3 3 1 Parkin co-regulated protein CLASP_N PF12348.3 CCU97609.1 - 0.011 15.1 2.5 1.3 8.2 0.2 3.4 2 1 1 3 3 3 0 CLASP N terminal DUF2435 PF10363.4 CCU97609.1 - 0.072 12.9 3.3 0.23 11.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Arm PF00514.18 CCU97609.1 - 0.17 11.7 1.3 3.6 7.5 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ABC_tran PF00005.22 CCU97610.1 - 1.5e-34 119.2 0.1 1.1e-16 61.3 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCU97610.1 - 1.8e-13 51.1 4.4 0.06 13.3 0.0 4.4 2 2 1 4 4 4 4 AAA domain SMC_N PF02463.14 CCU97610.1 - 7.2e-11 41.7 5.4 7.4e-05 22.0 0.3 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CCU97610.1 - 8.3e-08 31.6 1.6 0.22 10.5 0.1 4.6 5 0 0 5 5 5 3 AAA ATPase domain Fer4 PF00037.22 CCU97610.1 - 3.4e-07 29.5 2.5 6.3e-07 28.7 1.8 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain AAA_22 PF13401.1 CCU97610.1 - 7.4e-07 29.3 0.1 0.0019 18.3 0.0 2.6 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCU97610.1 - 5e-06 25.7 0.0 0.051 12.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA PF00004.24 CCU97610.1 - 5.3e-06 26.6 0.1 0.016 15.4 0.1 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CCU97610.1 - 1.2e-05 24.6 0.8 0.038 13.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 CCU97610.1 - 2.4e-05 24.0 1.4 0.0027 17.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 CCU97610.1 - 3.7e-05 23.2 0.1 0.027 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.2 CCU97610.1 - 4.6e-05 23.0 1.9 8.9e-05 22.1 1.3 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain AAA_17 PF13207.1 CCU97610.1 - 6.1e-05 23.8 0.1 0.53 11.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain Fer4_21 PF14697.1 CCU97610.1 - 0.00017 21.3 1.4 0.00037 20.3 1.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_33 PF13671.1 CCU97610.1 - 0.00025 20.9 0.2 0.076 12.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain Fer4_9 PF13187.1 CCU97610.1 - 0.00031 20.9 0.4 0.00086 19.5 0.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Miro PF08477.8 CCU97610.1 - 0.00031 21.2 0.0 0.51 10.8 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein VirE PF05272.6 CCU97610.1 - 0.00034 20.1 0.0 0.4 10.1 0.0 2.4 2 0 0 2 2 2 2 Virulence-associated protein E Fer4_7 PF12838.2 CCU97610.1 - 0.00035 20.9 0.3 0.00092 19.5 0.2 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 CCU97610.1 - 0.00054 19.7 2.2 0.0012 18.6 1.5 1.6 1 0 0 1 1 1 1 4Fe-4S binding domain RNA_helicase PF00910.17 CCU97610.1 - 0.00064 19.8 0.1 0.17 12.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 CCU97610.1 - 0.00083 19.3 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Fer4_10 PF13237.1 CCU97610.1 - 0.00086 19.0 0.4 0.0017 18.0 0.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_18 PF13238.1 CCU97610.1 - 0.0012 19.1 0.7 0.84 9.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 CCU97610.1 - 0.0015 18.3 0.0 2.8 7.9 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 CCU97610.1 - 0.002 17.8 1.9 0.27 10.9 0.1 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 CCU97610.1 - 0.0034 16.9 0.5 0.044 13.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_8 PF13183.1 CCU97610.1 - 0.004 17.1 0.1 0.009 16.0 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 CCU97610.1 - 0.0041 17.8 0.2 0.01 16.5 0.1 1.7 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain AAA_28 PF13521.1 CCU97610.1 - 0.0052 16.7 0.2 1.3 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CCU97610.1 - 0.008 15.0 0.0 0.59 8.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.10 CCU97610.1 - 0.012 14.2 0.0 1.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein SRP54 PF00448.17 CCU97610.1 - 0.013 14.9 3.8 0.3 10.5 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 CCU97610.1 - 0.015 15.6 0.8 0.015 15.6 0.5 2.7 2 1 1 3 3 2 0 AAA domain Fer4_18 PF13746.1 CCU97610.1 - 0.018 15.4 0.7 0.055 13.8 0.5 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.1 CCU97610.1 - 0.018 15.3 0.2 0.052 13.9 0.1 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 CCU97610.1 - 0.029 14.6 2.3 0.067 13.5 1.6 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain Thymidylate_kin PF02223.12 CCU97610.1 - 0.032 13.6 0.1 8.5 5.6 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase AAA_14 PF13173.1 CCU97610.1 - 0.042 13.7 1.6 8.9 6.2 0.1 3.2 2 2 0 2 2 2 0 AAA domain Fer4_3 PF12798.2 CCU97610.1 - 0.046 14.2 3.7 0.11 13.1 2.6 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain AAA_24 PF13479.1 CCU97610.1 - 0.05 13.1 1.2 0.6 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CCU97610.1 - 0.074 13.0 0.0 8 6.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ArgK PF03308.11 CCU97610.1 - 0.085 11.6 0.3 0.96 8.1 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 CCU97610.1 - 0.12 11.8 1.6 4.7 6.5 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 CCU97610.1 - 0.12 11.2 0.0 8.9 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_15 PF13459.1 CCU97610.1 - 0.29 11.7 2.6 0.42 11.2 0.8 2.0 2 0 0 2 2 1 0 4Fe-4S single cluster domain AAA_5 PF07728.9 CCU97610.1 - 0.41 10.3 3.4 2.2 8.0 0.1 3.1 3 1 0 4 4 3 0 AAA domain (dynein-related subfamily) SNF2_N PF00176.18 CCU97612.1 - 2e-41 141.7 0.0 3e-39 134.5 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 CCU97612.1 - 9.4e-06 25.2 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase KH_1 PF00013.24 CCU97613.1 - 3.1e-05 23.5 0.0 6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CCU97613.1 - 0.00022 20.8 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 CCU97613.1 - 0.054 13.1 0.1 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 KH domain FHA PF00498.21 CCU97614.1 - 2.2e-15 56.5 0.0 4.7e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 CCU97614.1 - 1.8e-07 30.8 12.1 2.9e-07 30.1 8.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCU97614.1 - 2.9e-05 24.0 4.1 5.7e-05 23.1 2.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CCU97614.1 - 0.0014 18.4 3.0 0.0028 17.4 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CCU97614.1 - 0.026 14.5 14.6 0.043 13.8 10.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 CCU97614.1 - 0.043 13.9 1.4 0.09 12.9 1.0 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.1 CCU97614.1 - 0.045 13.4 10.8 0.073 12.8 7.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CCU97614.1 - 0.057 13.0 11.7 0.097 12.3 8.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 CCU97614.1 - 0.07 13.1 1.0 0.14 12.2 0.7 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain PHD PF00628.24 CCU97614.1 - 3.2 7.5 6.8 5.5 6.7 4.7 1.4 1 0 0 1 1 1 0 PHD-finger DEAD PF00270.24 CCU97615.1 - 1.3e-46 158.1 0.0 8.3e-45 152.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU97615.1 - 6.2e-26 90.0 0.0 1.5e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCU97615.1 - 0.00036 20.4 0.9 0.02 14.7 0.0 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CCU97615.1 - 0.00038 18.9 0.0 0.0065 14.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) Nop14 PF04147.7 CCU97615.1 - 0.5 8.2 21.6 1 7.2 15.0 1.4 1 0 0 1 1 1 0 Nop14-like family IF-2B PF01008.12 CCU97616.1 - 1.2e-57 195.1 0.0 1.4e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pkinase PF00069.20 CCU97617.1 - 4.5e-56 189.8 0.0 5.6e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97617.1 - 9.1e-25 87.2 0.0 1.4e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Got1 PF04178.7 CCU97617.1 - 5.6e-16 58.7 9.9 1e-15 57.8 6.8 1.4 1 0 0 1 1 1 1 Got1/Sft2-like family Kinase-like PF14531.1 CCU97617.1 - 0.00099 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCU97617.1 - 0.055 12.5 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrhK PF14145.1 CCU97617.1 - 0.12 12.0 9.0 1.3 8.7 1.0 3.3 3 0 0 3 3 3 0 YrhK-like protein Lipase_GDSL PF00657.17 CCU97618.1 - 2.9e-19 69.8 0.0 3.6e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CCU97618.1 - 4.6e-09 36.6 1.6 7.4e-09 35.9 1.1 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Sec23_trunk PF04811.10 CCU97619.1 - 9.5e-58 195.4 0.0 1.5e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCU97619.1 - 1.6e-20 72.4 0.0 3.2e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CCU97619.1 - 4.2e-17 61.4 4.7 7.1e-17 60.6 3.3 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CCU97619.1 - 9e-16 58.1 0.0 1.6e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CCU97619.1 - 8.1e-07 28.6 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat RRM_1 PF00076.17 CCU97620.1 - 8.9e-07 28.4 0.0 2.1e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 CCU97620.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 PWI domain zf-CCCH PF00642.19 CCU97623.1 - 1.9e-13 49.7 28.8 2.8e-08 33.2 1.3 4.0 3 1 1 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 CCU97623.1 - 0.01 15.3 16.4 0.098 12.2 0.5 4.4 3 1 1 4 4 4 0 LRV protein FeS4 cluster NPIP PF06409.6 CCU97623.1 - 0.047 12.4 2.1 0.078 11.7 1.5 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) zf-CCCH_2 PF14608.1 CCU97623.1 - 0.067 13.2 19.5 0.3 11.1 0.3 4.8 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type Rtf2 PF04641.7 CCU97624.1 - 2.3e-33 115.5 0.0 2.6e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger Pkinase PF00069.20 CCU97626.1 - 4.5e-42 144.0 0.0 5.5e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97626.1 - 2.6e-16 59.4 0.0 3.3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCU97626.1 - 1.8e-05 24.6 2.3 3.7e-05 23.5 0.4 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCU97626.1 - 4e-05 22.7 0.0 8.7e-05 21.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CCU97626.1 - 8.8e-05 21.9 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 CCU97626.1 - 0.0034 16.9 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase MOZART1 PF12554.3 CCU97626.1 - 0.011 15.1 0.1 13 5.3 0.0 3.2 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated Kdo PF06293.9 CCU97626.1 - 0.052 12.6 0.1 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_20 PF00982.16 CCU97627.1 - 3.9e-147 490.5 0.0 4.9e-147 490.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CCU97627.1 - 1.3e-18 66.7 0.0 2.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase P16-Arc PF04699.9 CCU97628.1 - 1.6e-40 138.5 0.0 1.8e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Pkinase PF00069.20 CCU97629.1 - 1.4e-74 250.5 0.8 1.8e-74 250.2 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97629.1 - 1.9e-52 177.9 0.1 1.9e-52 177.9 0.1 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase PBD PF00786.23 CCU97629.1 - 2.3e-21 75.9 0.0 7.1e-21 74.3 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 CCU97629.1 - 2.5e-09 37.2 0.7 6.8e-09 35.8 0.5 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CCU97629.1 - 1.2e-07 30.9 0.0 3.3e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like PH_11 PF15413.1 CCU97629.1 - 0.0004 20.5 1.0 0.03 14.5 0.7 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 CCU97629.1 - 0.02 14.6 5.4 0.036 13.7 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family CAF-1_p150 PF11600.3 CCU97629.1 - 3 7.1 14.6 0.055 12.8 4.5 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 CCU97629.1 - 7.9 4.5 29.4 12 3.9 20.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FF PF01846.14 CCU97631.1 - 1e-30 105.4 0.2 5.9e-11 42.1 0.0 4.6 4 0 0 4 4 4 4 FF domain WW PF00397.21 CCU97631.1 - 9.4e-08 31.7 11.5 0.00014 21.6 1.9 2.6 2 0 0 2 2 2 2 WW domain HSP70 PF00012.15 CCU97632.1 - 4.2e-73 246.2 0.2 5.9e-73 245.7 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCU97632.1 - 3.1e-05 22.7 0.2 0.00026 19.6 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.3 CCU97632.1 - 0.00084 18.3 0.2 0.0039 16.1 0.2 1.9 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; Hydantoinase_A PF01968.13 CCU97632.1 - 0.0018 17.4 0.7 0.05 12.6 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 CCU97632.1 - 0.027 14.2 0.4 0.12 12.1 0.3 2.3 1 1 0 1 1 1 0 Cell division protein FtsA Guanylate_kin PF00625.16 CCU97633.1 - 6.7e-58 195.1 0.0 7.8e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 CCU97633.1 - 5.3e-09 36.3 1.8 1.4e-07 31.6 1.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 CCU97633.1 - 8.5e-08 32.1 0.1 3e-07 30.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCU97633.1 - 7.6e-07 29.3 0.0 3.6e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCU97633.1 - 2.6e-05 23.4 0.0 4.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCU97633.1 - 3.4e-05 24.6 0.0 9.8e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCU97633.1 - 5.2e-05 23.5 0.0 0.00029 21.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CCU97633.1 - 0.0011 19.1 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 CCU97633.1 - 0.0016 18.4 0.0 0.02 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CCU97633.1 - 0.0024 18.3 0.0 0.0046 17.4 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 CCU97633.1 - 0.0035 17.6 0.0 0.012 15.8 0.0 2.0 2 1 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.18 CCU97633.1 - 0.0043 16.9 0.0 0.009 15.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 CCU97633.1 - 0.006 16.7 0.0 0.019 15.1 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCU97633.1 - 0.0081 15.8 0.0 0.042 13.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 CCU97633.1 - 0.013 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 CCU97633.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CCU97633.1 - 0.014 14.8 0.1 0.042 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 CCU97633.1 - 0.015 15.0 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 CCU97633.1 - 0.016 14.9 0.0 0.053 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CCU97633.1 - 0.017 15.0 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CCU97633.1 - 0.039 13.6 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF4485 PF14846.1 CCU97633.1 - 0.072 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) TrwB_AAD_bind PF10412.4 CCU97633.1 - 0.078 11.5 0.0 4.1 5.9 0.0 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Septin PF00735.13 CCU97633.1 - 0.082 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Septin Histone PF00125.19 CCU97634.1 - 4.2e-14 52.4 0.1 5e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCU97634.1 - 0.00013 22.1 0.0 0.00017 21.6 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCU97634.1 - 0.00024 21.1 0.1 0.00047 20.1 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CCU97634.1 - 0.00027 20.8 0.1 0.00038 20.3 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 CCU97634.1 - 0.062 12.5 0.0 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nup35_RRM PF05172.8 CCU97635.1 - 5.8e-08 32.4 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CCU97635.1 - 0.026 14.2 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 CCU97636.1 - 2.1e-68 230.3 0.0 2.5e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97636.1 - 2.1e-32 112.2 0.0 2.6e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU97636.1 - 0.00016 20.7 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCU97636.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCU97636.1 - 0.0097 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 CCU97636.1 - 0.035 13.1 0.1 0.11 11.5 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tim17 PF02466.14 CCU97637.1 - 3.6e-21 75.5 0.0 6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HAD_2 PF13419.1 CCU97638.1 - 6.4e-07 29.7 0.0 5.1e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCU97638.1 - 4.3e-05 24.0 0.0 6.9e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CCU97638.1 - 0.042 13.7 0.0 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Snf7 PF03357.16 CCU97639.1 - 1.3e-39 135.2 20.9 1.6e-39 134.9 14.5 1.0 1 0 0 1 1 1 1 Snf7 DUF4559 PF15112.1 CCU97639.1 - 0.0013 18.0 7.2 0.0016 17.6 5.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) DUF1569 PF07606.6 CCU97639.1 - 0.026 14.4 6.6 0.034 14.0 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1569) NPV_P10 PF05531.7 CCU97639.1 - 0.043 14.0 4.1 0.1 12.8 0.7 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Soyouz_module PF14313.1 CCU97639.1 - 0.097 12.2 0.0 5.5 6.6 0.0 3.0 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Prefoldin_2 PF01920.15 CCU97639.1 - 0.2 11.4 13.9 0.55 10.0 0.0 3.4 3 1 1 4 4 3 0 Prefoldin subunit Phage_GP20 PF06810.6 CCU97639.1 - 0.39 10.1 8.1 1.2 8.5 5.6 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 SMAP PF15477.1 CCU97639.1 - 0.93 9.8 5.8 0.67 10.2 0.8 3.0 1 1 2 3 3 3 0 Small acidic protein family Atg14 PF10186.4 CCU97639.1 - 1 8.2 11.2 2 7.3 7.7 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF848 PF05852.6 CCU97639.1 - 1.1 9.1 8.0 0.59 9.9 3.6 1.8 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF342 PF03961.8 CCU97639.1 - 1.3 7.3 9.4 0.93 7.8 4.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) GrpE PF01025.14 CCU97639.1 - 1.7 8.1 9.1 2.2 7.8 2.8 2.4 1 1 1 2 2 2 0 GrpE Mnd1 PF03962.10 CCU97639.1 - 1.9 8.1 12.4 13 5.3 8.6 1.9 1 1 0 1 1 1 0 Mnd1 family TMF_DNA_bd PF12329.3 CCU97639.1 - 4.9 7.0 11.9 1.8 8.4 2.1 3.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2730 PF10805.3 CCU97639.1 - 7.1 6.4 10.4 23 4.7 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) IncA PF04156.9 CCU97639.1 - 8.2 5.9 11.0 26 4.3 2.2 2.3 1 1 1 2 2 2 0 IncA protein DUF4140 PF13600.1 CCU97639.1 - 9.2 6.7 8.5 5.3 7.5 0.4 2.8 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) BAR PF03114.13 CCU97640.1 - 5.5e-37 127.4 0.0 1.1e-36 126.5 0.0 1.4 1 1 0 1 1 1 1 BAR domain DUF826 PF05696.6 CCU97640.1 - 0.062 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF826) Metallophos PF00149.23 CCU97641.1 - 1.7e-26 92.8 0.0 3.2e-26 91.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CCU97641.1 - 2.1e-17 62.4 4.5 1.4e-10 40.6 0.2 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCU97641.1 - 1.3e-15 56.1 1.0 1.3e-05 24.5 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat PPP5 PF08321.7 CCU97641.1 - 2.9e-09 36.8 0.0 0.002 18.1 0.0 2.5 1 1 1 2 2 2 2 PPP5 TPR repeat region TPR_2 PF07719.12 CCU97641.1 - 3.2e-09 35.9 0.4 0.025 14.4 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCU97641.1 - 3.3e-06 26.8 1.8 0.028 14.5 0.1 3.2 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCU97641.1 - 0.0012 19.4 0.9 0.16 12.6 0.3 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCU97641.1 - 0.0013 18.3 0.3 0.76 9.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCU97641.1 - 0.0019 17.9 0.2 0.059 13.2 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCU97641.1 - 0.015 15.8 1.4 5.2 7.9 0.1 3.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCU97641.1 - 0.028 14.3 1.1 0.21 11.5 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCU97641.1 - 0.11 12.4 0.4 0.95 9.3 0.0 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 CCU97641.1 - 0.6 10.4 4.0 3.3 8.1 0.9 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Ribosomal_L21p PF00829.16 CCU97642.1 - 9.6e-10 38.4 0.3 1.8e-07 31.2 0.1 2.2 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein Dynamin_M PF01031.15 CCU97644.1 - 4.8e-111 370.2 0.0 7.3e-111 369.6 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CCU97644.1 - 3.8e-56 189.5 0.0 9.7e-56 188.1 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CCU97644.1 - 8.2e-26 89.7 5.0 8.7e-26 89.6 2.3 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCU97644.1 - 0.0039 17.1 0.0 0.013 15.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCU97644.1 - 0.032 14.7 0.0 0.091 13.2 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein MBOAT PF03062.14 CCU97646.1 - 2e-13 50.1 5.9 2.2e-13 50.0 4.1 1.0 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CCU97646.1 - 0.11 12.5 1.1 0.17 12.0 0.7 1.3 1 1 0 1 1 1 0 Membrane bound O-acyl transferase family UIM PF02809.15 CCU97648.1 - 0.0057 16.1 2.7 0.0057 16.1 1.9 2.6 2 0 0 2 2 2 1 Ubiquitin interaction motif NIF PF03031.13 CCU97648.1 - 0.011 15.4 0.3 0.15 11.7 0.0 2.4 2 1 0 2 2 2 0 NLI interacting factor-like phosphatase DUF3138 PF11336.3 CCU97648.1 - 0.17 10.0 4.3 0.32 9.1 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RasGEF PF00617.14 CCU97649.1 - 6.4e-42 143.4 0.1 1e-41 142.7 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CCU97649.1 - 7.4e-05 22.8 0.0 0.00023 21.1 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif BNR PF02012.15 CCU97650.1 - 1.6e-06 27.0 44.0 0.51 10.3 0.2 12.0 12 0 0 12 12 12 5 BNR/Asp-box repeat PSII_BNR PF14870.1 CCU97650.1 - 0.003 16.6 2.0 0.83 8.5 0.0 4.2 4 1 0 4 4 4 2 Photosynthesis system II assembly factor YCF48 CHB_HEX_C_1 PF13290.1 CCU97650.1 - 0.056 13.2 0.0 55 3.6 0.0 3.7 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Dus PF01207.12 CCU97651.1 - 7.8e-18 64.3 0.0 7.5e-09 34.8 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) ASF1_hist_chap PF04729.8 CCU97652.1 - 1.6e-34 118.8 0.0 2.1e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Sterol_MT_C PF08498.5 CCU97653.1 - 1.2e-26 92.4 0.3 1.8e-26 91.8 0.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 CCU97653.1 - 6.2e-19 68.0 0.0 9.2e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCU97653.1 - 1.1e-18 67.5 0.0 2e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCU97653.1 - 3.5e-16 59.3 0.0 5.2e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCU97653.1 - 6.3e-14 51.6 0.0 8.8e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CCU97653.1 - 9.4e-14 51.9 0.0 3.6e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCU97653.1 - 1.9e-12 47.5 0.0 5e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCU97653.1 - 6.8e-12 45.4 0.0 1.7e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCU97653.1 - 2.3e-10 40.7 0.0 4.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCU97653.1 - 8.1e-07 28.3 0.0 1.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 CCU97653.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 CCU97653.1 - 7.3e-06 25.6 0.1 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 CCU97653.1 - 3e-05 23.4 0.0 6.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 CCU97653.1 - 0.00037 21.2 0.0 0.0019 19.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 CCU97653.1 - 0.002 17.2 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MetW PF07021.7 CCU97653.1 - 0.0042 16.4 0.0 0.0077 15.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.13 CCU97653.1 - 0.0045 16.2 0.0 0.007 15.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Met_10 PF02475.11 CCU97653.1 - 0.0046 16.5 0.0 0.0057 16.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Spermine_synth PF01564.12 CCU97653.1 - 0.012 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase UPF0020 PF01170.13 CCU97653.1 - 0.024 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 CCU97653.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 CCU97653.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 CCU97653.1 - 0.12 11.4 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase LSM PF01423.17 CCU97654.1 - 6.9e-12 44.7 0.0 8.1e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF4002 PF13164.1 CCU97654.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4002) DHO_dh PF01180.16 CCU97655.1 - 2.9e-94 315.3 0.0 6.1e-94 314.2 0.0 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CCU97655.1 - 0.0063 15.4 0.1 0.15 10.8 0.1 2.5 2 1 0 2 2 2 1 FMN-dependent dehydrogenase zf-H2C2_2 PF13465.1 CCU97656.1 - 3.9e-23 80.5 23.9 1.7e-06 28.0 0.1 5.5 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 CCU97656.1 - 7.5e-22 76.3 23.1 1.8e-05 24.7 1.3 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCU97656.1 - 6.7e-15 54.2 20.5 0.00036 20.6 0.5 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCU97656.1 - 4.2e-07 29.9 6.8 0.02 15.0 0.1 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCU97656.1 - 0.00073 19.3 11.9 0.027 14.3 0.4 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 CCU97656.1 - 0.00093 19.3 11.2 0.24 11.6 0.2 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-TRAF PF02176.13 CCU97656.1 - 0.0058 16.9 8.7 0.11 12.9 0.3 3.1 2 1 1 3 3 3 2 TRAF-type zinc finger Viral_helicase1 PF01443.13 CCU97656.1 - 0.061 12.8 0.1 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CCAP PF11105.3 CCU97656.1 - 4.9 6.8 8.5 8.9 6.0 0.5 3.1 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a Ogr_Delta PF04606.7 CCU97656.1 - 6.7 6.4 7.6 7.5 6.2 0.3 2.8 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger SMC_N PF02463.14 CCU97657.1 - 2e-73 246.2 0.0 2.6e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCU97657.1 - 3.4e-26 91.5 0.0 9.9e-26 90.0 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCU97657.1 - 4.6e-15 56.3 0.0 2.7e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CCU97657.1 - 1.1e-09 38.9 4.6 1.1e-09 38.9 3.2 4.0 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.1 CCU97657.1 - 1.7e-05 24.0 0.0 0.0034 16.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CCU97657.1 - 6.3e-05 22.4 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CCU97657.1 - 0.042 14.1 8.9 0.22 11.8 0.0 4.1 5 0 0 5 5 5 0 ABC transporter AAA_13 PF13166.1 CCU97657.1 - 0.95 7.8 48.0 1.2 7.4 8.5 5.9 3 2 2 5 5 5 0 AAA domain Racemase_4 PF13615.1 CCU97658.1 - 3.4e-08 33.6 0.3 1.6e-07 31.4 0.2 2.2 1 1 0 1 1 1 1 Putative alanine racemase DUF2418 PF10332.4 CCU97658.1 - 8.1e-05 22.8 0.6 8.1e-05 22.8 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) MCM_bind PF09739.4 CCU97658.1 - 0.0099 15.4 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor CKS PF01111.14 CCU97659.1 - 1.5e-17 63.1 0.0 1.7e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Aldo_ket_red PF00248.16 CCU97660.1 - 6.6e-56 189.2 0.0 8.1e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RCC1 PF00415.13 CCU97661.1 - 2.2e-28 98.1 4.1 1.3e-10 41.3 0.1 7.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCU97661.1 - 3.3e-12 45.6 21.9 5e-09 35.5 0.2 7.2 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat DUF3558 PF12079.3 CCU97661.1 - 0.0012 18.5 0.1 0.019 14.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3558) PQQ_3 PF13570.1 CCU97661.1 - 0.075 13.3 0.1 3.3 8.1 0.0 3.1 2 0 0 2 2 2 0 PQQ-like domain tRNA-synt_2b PF00587.20 CCU97662.1 - 2.8e-67 225.6 0.1 4.5e-67 224.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCU97662.1 - 1.2e-22 79.6 0.4 1.1e-21 76.5 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain Mcp5_PH PF12814.2 CCU97663.1 - 6.4e-32 110.0 0.0 3.4e-31 107.7 0.0 2.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3584 PF12128.3 CCU97663.1 - 0.00024 18.6 22.6 0.00024 18.6 15.7 10.2 3 1 6 10 10 10 3 Protein of unknown function (DUF3584) Nop10p PF04135.7 CCU97664.1 - 1.6e-20 72.5 0.1 1.8e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family EMP24_GP25L PF01105.19 CCU97665.1 - 4.5e-31 107.9 0.0 5.6e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PUB PF09409.5 CCU97665.1 - 0.042 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 PUB domain Mycobact_memb PF05423.8 CCU97665.1 - 0.14 11.8 0.5 3.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Mycobacterium membrane protein zf-UBR PF02207.15 CCU97666.1 - 1.4e-12 47.1 7.2 1.4e-12 47.1 5.0 3.8 3 1 1 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 CCU97666.1 - 0.0012 18.4 5.2 0.0012 18.4 3.6 3.6 3 2 0 3 3 3 1 PHD-finger Pyrid_oxidase_2 PF13883.1 CCU97667.1 - 3e-22 79.1 0.0 5e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PrsW-protease PF13367.1 CCU97667.1 - 1.9e-13 50.0 3.8 4.6e-13 48.7 2.6 1.7 1 1 0 1 1 1 1 Protease prsW family VRR_NUC PF08774.6 CCU97668.1 - 3.7e-18 65.3 0.0 1.2e-17 63.7 0.0 2.0 1 0 0 1 1 1 1 VRR-NUC domain SAP PF02037.22 CCU97668.1 - 0.093 12.2 0.6 0.25 10.8 0.4 1.8 1 0 0 1 1 1 0 SAP domain Myosin_head PF00063.16 CCU97669.1 - 2.1e-238 792.8 0.0 2.1e-238 792.8 0.0 2.6 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.14 CCU97669.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 CCU97669.1 - 0.11 12.5 0.0 0.11 12.5 0.0 4.0 4 1 0 4 4 4 0 AAA domain AAA_19 PF13245.1 CCU97669.1 - 0.16 11.7 0.0 0.16 11.7 0.0 3.0 3 0 0 3 3 3 0 Part of AAA domain MOZ_SAS PF01853.13 CCU97670.1 - 1.2e-77 259.3 0.5 1.7e-77 258.9 0.4 1.1 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 CCU97670.1 - 7e-12 44.8 27.4 3.8e-11 42.5 3.2 4.3 2 1 1 3 3 3 2 PHD-finger zf-RING_2 PF13639.1 CCU97670.1 - 0.019 14.7 6.1 0.019 14.7 4.2 3.5 4 1 0 4 4 4 0 Ring finger domain WD40 PF00400.27 CCU97671.1 - 2e-70 230.3 19.0 1e-11 44.1 0.2 6.2 5 1 1 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 CCU97671.1 - 2.2e-09 36.0 7.2 0.00056 18.1 0.1 3.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCU97671.1 - 2.9e-06 26.3 2.8 0.076 11.7 0.3 3.5 1 1 1 3 3 3 3 Nup133 N terminal like PIN_3 PF13470.1 CCU97671.1 - 0.056 14.1 1.4 0.14 12.7 0.9 1.6 1 0 0 1 1 1 0 PIN domain Hira PF07569.6 CCU97671.1 - 0.074 12.2 0.0 5.1 6.2 0.0 2.3 2 0 0 2 2 2 0 TUP1-like enhancer of split DUF1652 PF07865.6 CCU97671.1 - 0.11 12.0 0.0 21 4.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) Myb_CC_LHEQLE PF14379.1 CCU97671.1 - 0.14 11.7 2.2 0.26 10.8 1.6 1.4 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif DUF1682 PF07946.9 CCU97671.1 - 0.14 10.9 1.9 0.22 10.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Kinesin PF00225.18 CCU97672.1 - 4.1e-24 84.8 0.0 5.7e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DAHP_synth_1 PF00793.15 CCU97673.1 - 2.1e-92 308.7 0.0 2.4e-92 308.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family SRX PF09201.5 CCU97673.1 - 0.05 13.2 0.0 2.1 8.0 0.1 2.2 2 0 0 2 2 2 0 SRX CBFD_NFYB_HMF PF00808.18 CCU97674.1 - 1.8e-17 63.1 0.2 3e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Toxin_63 PF15541.1 CCU97674.1 - 0.062 13.2 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 63 DUF1127 PF06568.6 CCU97674.1 - 0.091 12.1 0.8 0.18 11.2 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) FTHFS PF01268.14 CCU97675.1 - 4.8e-262 869.9 0.1 1.1e-261 868.7 0.0 1.6 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CCU97675.1 - 3.8e-60 201.6 2.1 3.8e-60 201.6 1.4 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CCU97675.1 - 1e-34 119.0 0.1 1.1e-33 115.7 0.1 2.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SAM_2 PF07647.12 CCU97676.1 - 7.1e-11 41.7 0.0 2.2e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CCU97676.1 - 9.7e-08 32.0 0.1 3.2e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) YebO PF13974.1 CCU97676.1 - 2.9 7.7 8.4 0.89 9.3 3.3 1.9 2 0 0 2 2 2 0 YebO-like protein ATP-synt_ab PF00006.20 CCU97677.1 - 5.3e-63 212.3 0.0 9.8e-63 211.5 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCU97677.1 - 1.4e-24 86.7 0.4 2.7e-24 85.8 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCU97677.1 - 1.7e-24 85.7 1.5 1.7e-24 85.7 1.0 2.2 3 0 0 3 3 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_16 PF13191.1 CCU97677.1 - 0.0084 16.1 0.2 0.033 14.1 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 CCU97677.1 - 0.009 15.4 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CCU97677.1 - 0.018 14.7 0.2 0.98 9.1 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CCU97677.1 - 0.023 13.9 0.1 0.042 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 CCU97677.1 - 0.024 14.3 0.1 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 CCU97677.1 - 0.028 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 CCU97677.1 - 0.04 13.0 0.2 0.086 11.9 0.1 1.6 1 0 0 1 1 1 0 KaiC AAA PF00004.24 CCU97677.1 - 0.041 14.0 0.0 0.48 10.6 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCU97677.1 - 0.084 13.0 0.0 0.28 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CCU97677.1 - 0.093 11.5 1.3 0.099 11.4 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 CCU97677.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Septin PF00735.13 CCU97678.1 - 2.3e-99 331.9 0.0 3e-99 331.5 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CCU97678.1 - 2.3e-07 30.7 0.0 4.6e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCU97678.1 - 3.9e-06 26.4 0.2 7.4e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CCU97678.1 - 2.4e-05 23.5 0.1 4.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CCU97678.1 - 6.4e-05 22.1 0.0 6.4e-05 22.1 0.0 2.2 3 0 0 3 3 3 1 AIG1 family Dynamin_N PF00350.18 CCU97678.1 - 0.00067 19.5 0.1 0.54 10.0 0.1 2.4 1 1 1 2 2 2 2 Dynamin family Gtr1_RagA PF04670.7 CCU97678.1 - 0.0008 18.6 1.9 0.001 18.2 0.0 2.1 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 CCU97678.1 - 0.0034 16.8 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 CCU97678.1 - 0.0038 16.6 0.0 0.0083 15.5 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 CCU97678.1 - 0.0062 16.8 0.1 0.011 15.9 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CCU97678.1 - 0.017 14.6 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 CCU97678.1 - 0.021 14.9 0.0 0.96 9.5 0.0 2.5 3 0 0 3 3 2 0 AAA domain RuvB_N PF05496.7 CCU97678.1 - 0.026 13.5 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus PduV-EutP PF10662.4 CCU97678.1 - 0.027 13.9 0.1 1.9 7.9 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CCU97678.1 - 0.03 14.8 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein T2SE PF00437.15 CCU97678.1 - 0.047 12.5 0.0 0.11 11.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_32 PF13654.1 CCU97678.1 - 0.061 11.9 1.7 0.19 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 CCU97678.1 - 0.068 12.5 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Ras family DUF87 PF01935.12 CCU97678.1 - 0.1 12.3 0.2 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 SCAMP PF04144.8 CCU97679.1 - 2.1e-46 158.0 11.1 2.5e-46 157.7 7.7 1.1 1 0 0 1 1 1 1 SCAMP family DUF1700 PF08006.6 CCU97679.1 - 1.4 8.1 5.7 2.4 7.4 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Peptidase_U4 PF03419.8 CCU97679.1 - 3.1 6.7 9.8 4 6.4 6.8 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Bromodomain PF00439.20 CCU97680.1 - 6.5e-42 141.3 0.2 5.9e-20 70.9 0.0 2.3 2 0 0 2 2 2 2 Bromodomain SpoVG PF04026.7 CCU97680.1 - 0.06 13.3 0.1 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 SpoVG Sec39 PF08314.6 CCU97681.1 - 3.4e-18 64.9 0.0 5.5e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF3419 PF11899.3 CCU97682.1 - 2.2e-139 464.3 0.0 3e-139 463.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 CCU97682.1 - 1.8e-10 40.7 0.0 4.5e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCU97682.1 - 3.3e-08 33.2 0.0 7.8e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCU97682.1 - 5.5e-08 32.2 0.0 4.3e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CCU97682.1 - 1.9e-07 31.4 0.0 1.3e-05 25.6 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCU97682.1 - 1.2e-06 28.9 0.0 3.5e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCU97682.1 - 0.0001 22.8 0.0 0.00038 21.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCU97682.1 - 0.00012 22.4 0.0 0.00073 19.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 CCU97682.1 - 0.06 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Adaptin_N PF01602.15 CCU97683.1 - 2.1e-93 313.4 0.2 3.7e-93 312.6 0.2 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCU97683.1 - 3.7e-05 23.6 1.1 0.0098 15.7 0.0 3.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CCU97683.1 - 0.00011 22.4 13.6 0.45 10.8 0.2 6.5 2 1 3 5 5 5 2 HEAT repeats HEAT PF02985.17 CCU97683.1 - 0.0049 16.8 5.6 6.7 7.0 0.0 5.8 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 CCU97683.1 - 2.9 8.4 7.6 3.5 8.2 0.2 4.8 5 1 1 6 6 6 0 HEAT-like repeat GATase PF00117.23 CCU97684.1 - 0.049 13.0 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Tim54 PF11711.3 CCU97685.1 - 2.6e-57 194.1 0.1 4.7e-57 193.3 0.0 1.5 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SH3BP5 PF05276.9 CCU97685.1 - 0.0018 17.6 4.1 0.31 10.3 0.1 2.9 3 0 0 3 3 3 2 SH3 domain-binding protein 5 (SH3BP5) Methyltransf_31 PF13847.1 CCU97686.1 - 0.0045 16.5 0.0 0.026 14.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCU97686.1 - 0.052 14.0 0.1 0.28 11.7 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain PNP_UDP_1 PF01048.15 CCU97687.1 - 4.4e-32 110.9 0.1 5.2e-32 110.6 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4193 PF13834.1 CCU97687.1 - 0.077 13.1 0.1 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) Pkinase PF00069.20 CCU97688.1 - 1.9e-58 197.6 0.0 4.9e-58 196.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain mRNA_triPase PF02940.10 CCU97688.1 - 5.3e-49 166.8 0.1 7.6e-49 166.3 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Pkinase_Tyr PF07714.12 CCU97688.1 - 1.7e-32 112.5 0.0 3.7e-32 111.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CCU97688.1 - 0.0042 16.1 0.5 0.0075 15.3 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCU97688.1 - 0.039 12.9 0.1 0.23 10.4 0.0 1.9 2 0 0 2 2 2 0 Kinase-like FAT PF02259.18 CCU97689.1 - 7.3e-113 377.1 0.1 7.3e-113 377.1 0.1 2.1 3 0 0 3 3 3 1 FAT domain MutS_V PF00488.16 CCU97689.1 - 2.9e-75 252.7 0.0 4.7e-75 252.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V PI3_PI4_kinase PF00454.22 CCU97689.1 - 2.2e-54 184.4 0.5 5e-54 183.2 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 CCU97689.1 - 3.1e-54 183.2 0.0 1.5e-53 181.0 0.0 2.3 2 0 0 2 2 1 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 CCU97689.1 - 3.4e-41 139.3 0.2 3.4e-41 139.3 0.2 2.5 2 0 0 2 2 2 1 Rapamycin binding domain MutS_III PF05192.13 CCU97689.1 - 1.4e-40 139.2 3.3 1.4e-40 139.2 2.3 2.6 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.15 CCU97689.1 - 5.9e-34 116.4 0.0 1.4e-33 115.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CCU97689.1 - 4e-11 43.1 0.0 1.2e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 CCU97689.1 - 8.2e-07 29.1 0.0 2.1e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV FATC PF02260.15 CCU97689.1 - 1.4e-06 27.5 0.0 3.3e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 CCU97689.1 - 1.4e-05 24.7 25.1 0.051 13.6 0.0 10.8 13 0 0 13 13 11 2 HEAT repeat HEAT_EZ PF13513.1 CCU97689.1 - 0.00037 20.8 39.0 0.014 15.8 0.0 12.8 13 1 4 17 17 16 3 HEAT-like repeat TPR_19 PF14559.1 CCU97689.1 - 0.0005 20.3 3.4 0.96 9.8 0.0 4.9 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF1517 PF07466.6 CCU97689.1 - 0.11 11.4 0.0 0.32 9.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Cnd1 PF12717.2 CCU97689.1 - 0.2 11.4 0.1 7 6.4 0.0 3.6 3 0 0 3 3 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 CCU97689.1 - 0.65 8.2 4.7 10 4.2 0.2 3.7 3 1 0 3 3 3 0 Adaptin N terminal region PFU PF09070.6 CCU97690.1 - 2.1e-33 114.7 0.0 3.4e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 CCU97690.1 - 6.1e-31 105.1 14.7 4.9e-07 29.3 0.5 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat PUL PF08324.6 CCU97690.1 - 2.3e-18 65.9 0.0 3.5e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain DnaG_DnaB_bind PF08278.6 CCU97690.1 - 0.026 14.7 0.1 0.18 12.0 0.0 2.4 3 0 0 3 3 3 0 DNA primase DnaG DnaB-binding Endonuclease_NS PF01223.18 CCU97691.1 - 5.9e-52 176.3 0.0 9.2e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease PQ-loop PF04193.9 CCU97691.1 - 0.0082 15.6 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 PQ loop repeat Aminotran_3 PF00202.16 CCU97692.1 - 3.3e-109 364.8 0.0 4.4e-109 364.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CCU97692.1 - 4.7e-05 22.4 0.0 8.4e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCU97692.1 - 0.0015 17.7 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CCU97692.1 - 0.021 13.5 0.2 0.058 12.1 0.0 1.8 3 0 0 3 3 3 0 Aminotransferase class-V Ribosomal_L7Ae PF01248.21 CCU97694.1 - 2.7e-23 81.2 0.1 5.1e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SMN PF06003.7 CCU97694.1 - 0.0047 16.0 3.0 0.0073 15.4 2.1 1.2 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Ycf1 PF05758.7 CCU97694.1 - 0.2 9.3 3.8 0.16 9.6 2.6 1.1 1 0 0 1 1 1 0 Ycf1 NARP1 PF12569.3 CCU97694.1 - 0.35 9.5 13.5 0.46 9.1 9.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Baculo_PP31 PF05311.6 CCU97694.1 - 0.36 10.0 11.2 0.66 9.1 7.8 1.5 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FAM176 PF14851.1 CCU97694.1 - 1.8 8.2 5.6 3.4 7.3 3.9 1.5 1 0 0 1 1 1 0 FAM176 family YqfQ PF14181.1 CCU97694.1 - 5.3 7.0 12.5 11 6.0 8.7 1.6 1 0 0 1 1 1 0 YqfQ-like protein YebO PF13974.1 CCU97694.1 - 5.5 6.8 8.4 13 5.6 5.8 1.7 1 0 0 1 1 1 0 YebO-like protein Med19 PF10278.4 CCU97694.1 - 5.7 6.5 19.8 11 5.6 13.7 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Paramyxo_ncap PF00973.14 CCU97694.1 - 6.2 5.3 7.6 8.4 4.9 5.3 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Peroxin-13_N PF04088.8 CCU97695.1 - 1.5e-50 171.2 0.0 2.5e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region tRNA-synt_1b PF00579.20 CCU97695.1 - 4.1e-29 101.6 0.1 7.1e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pex2_Pex12 PF04757.9 CCU97695.1 - 0.0093 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Ribosomal_L16 PF00252.13 CCU97696.1 - 7.6e-32 109.8 0.1 1e-31 109.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF3212 PF11486.3 CCU97696.1 - 0.14 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) Rep_fac-A_C PF08646.5 CCU97698.1 - 2.8e-51 173.0 0.1 9.8e-49 164.8 0.0 2.6 3 0 0 3 3 3 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 CCU97698.1 - 7.8e-13 48.0 0.1 3.7e-10 39.5 0.0 3.3 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 CCU97698.1 - 4.3e-08 32.8 0.2 1.1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain PH_9 PF15410.1 CCU97699.1 - 6.9e-09 35.8 0.1 0.00046 20.3 0.1 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.24 CCU97699.1 - 9.7e-09 35.3 0.0 6.1e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 CCU97699.1 - 0.074 13.3 0.0 7.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Ist1 PF03398.9 CCU97700.1 - 5.3e-27 94.2 2.4 9.6e-16 57.6 0.0 2.0 1 1 1 2 2 2 2 Regulator of Vps4 activity in the MVB pathway DNA_primase_S PF01896.14 CCU97701.1 - 4.8e-51 172.3 0.0 8.3e-51 171.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Pyridoxal_deC PF00282.14 CCU97702.1 - 1.5e-67 227.6 0.0 2e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 CCU97702.1 - 1.2e-06 27.8 0.0 2.7e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CCU97702.1 - 8e-05 21.5 0.0 0.00013 20.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Pkinase PF00069.20 CCU97703.1 - 6.8e-70 235.1 0.1 9.7e-70 234.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97703.1 - 1.6e-42 145.3 0.0 2.3e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CCU97703.1 - 3.5e-30 103.7 0.0 8e-15 54.5 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 CCU97703.1 - 1e-06 27.9 0.0 4.5e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF4520 PF15016.1 CCU97703.1 - 0.0017 17.9 0.0 0.7 9.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4520) BRCA-2_OB1 PF09103.5 CCU97704.1 - 3.3e-25 88.0 0.0 4.7e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 CCU97704.1 - 6.2e-06 25.9 0.9 9.5e-06 25.3 0.6 1.2 1 0 0 1 1 1 1 BRCA2, helical SIS PF01380.17 CCU97705.1 - 2.7e-58 195.2 0.3 7.2e-33 112.9 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CCU97705.1 - 5.8e-28 97.6 0.0 7.6e-20 70.9 0.0 2.3 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCU97705.1 - 5.6e-21 74.8 0.0 1.3e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CCU97705.1 - 4.7e-14 52.1 0.0 9.5e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CCU97705.1 - 2.5e-07 29.6 0.0 4.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 CCU97705.1 - 0.0094 15.6 0.1 0.06 13.0 0.0 2.2 2 0 0 2 2 2 1 SIS domain Plasmid_Txe PF06769.8 CCU97705.1 - 0.011 15.5 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 Plasmid encoded toxin Txe DEAD_2 PF06733.10 CCU97706.1 - 6.1e-46 155.9 0.0 9.9e-46 155.3 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 CCU97706.1 - 1.4e-25 90.1 0.0 4.4e-25 88.5 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_13 PF13166.1 CCU97708.1 - 0.0082 14.6 28.3 0.0068 14.9 17.9 1.7 1 1 1 2 2 2 2 AAA domain ATG16 PF08614.6 CCU97708.1 - 2.3 7.9 55.5 0.11 12.2 14.1 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Ribosomal_S10 PF00338.17 CCU97709.1 - 4.1e-30 103.4 0.3 4.8e-30 103.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L18e PF00828.14 CCU97710.1 - 2.4e-31 108.7 0.1 3.2e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 3HCDH_N PF02737.13 CCU97712.1 - 4.7e-56 189.2 5.8 6.4e-56 188.8 4.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CCU97712.1 - 2.8e-32 110.9 0.0 7.7e-32 109.5 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ThiF PF00899.16 CCU97712.1 - 0.0002 21.2 0.4 0.00032 20.5 0.3 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 CCU97712.1 - 0.0013 17.8 0.7 0.0021 17.0 0.5 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 CCU97712.1 - 0.0036 17.0 2.3 0.0091 15.7 1.6 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 CCU97712.1 - 0.0042 16.6 1.2 0.0066 16.0 0.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 CCU97712.1 - 0.008 15.5 2.6 0.029 13.7 1.8 1.8 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ribosomal_L11 PF00298.14 CCU97712.1 - 0.026 14.6 0.8 0.077 13.1 0.2 2.1 2 0 0 2 2 2 0 Ribosomal protein L11, RNA binding domain Pyr_redox PF00070.22 CCU97712.1 - 0.04 14.3 0.3 0.077 13.4 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 CCU97712.1 - 0.053 13.3 6.2 0.92 9.3 4.3 2.2 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1104 PF06518.6 CCU97712.1 - 0.067 13.3 1.5 3.7 7.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) F420_oxidored PF03807.12 CCU97712.1 - 0.17 12.3 4.1 3.7 8.0 2.8 2.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glycos_transf_2 PF00535.21 CCU97713.1 - 2.2e-30 105.5 0.0 2.8e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CCU97713.1 - 4.3e-12 46.3 0.0 7.1e-12 45.6 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CCU97713.1 - 1.4e-07 30.8 0.0 1.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CCU97713.1 - 0.00021 20.6 0.0 0.00048 19.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_7N PF13733.1 CCU97713.1 - 0.045 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_4 PF13704.1 CCU97713.1 - 0.073 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 WD40 PF00400.27 CCU97714.1 - 7.1e-39 130.3 6.7 8e-12 44.5 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 CCU97714.1 - 1.1e-22 79.8 9.6 2e-22 79.0 6.6 1.4 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 CCU97714.1 - 0.0004 20.1 0.0 0.0015 18.2 0.0 1.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Pribosyltran_N PF13793.1 CCU97715.1 - 3.6e-43 145.9 0.1 4.8e-42 142.3 0.0 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CCU97715.1 - 1.5e-34 119.3 0.1 2.7e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CCU97715.1 - 4.9e-08 32.7 0.2 3.6e-07 29.9 0.1 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCU97715.1 - 0.011 15.0 0.1 0.018 14.2 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase CheW PF01584.14 CCU97715.1 - 0.07 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 CheW-like domain LSM PF01423.17 CCU97716.1 - 2.2e-14 52.7 0.7 2.7e-14 52.4 0.5 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.12 CCU97716.1 - 0.13 12.0 0.5 0.22 11.2 0.4 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain XPG_N PF00752.12 CCU97717.1 - 3e-26 91.6 0.0 5.4e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCU97717.1 - 5.6e-26 90.4 0.0 9.8e-26 89.6 0.0 1.4 1 0 0 1 1 1 1 XPG I-region TPR_2 PF07719.12 CCU97717.1 - 0.0004 20.0 0.0 0.00097 18.8 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat XPG_I_2 PF12813.2 CCU97717.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing 5_3_exonuc PF01367.15 CCU97717.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TPR_9 PF13371.1 CCU97717.1 - 0.027 14.3 0.3 0.085 12.7 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCU97717.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat HCNGP PF07818.8 CCU97718.1 - 1e-14 54.3 0.0 1.9e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein TFIIIC_sub6 PF10419.4 CCU97718.1 - 5.1e-09 35.4 0.4 9.9e-09 34.5 0.3 1.4 1 0 0 1 1 1 1 TFIIIC subunit UDPG_MGDP_dh_N PF03721.9 CCU97719.1 - 1.8e-54 183.9 0.1 4.3e-54 182.6 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 CCU97719.1 - 1.1e-36 125.1 0.1 4.7e-36 123.1 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 CCU97719.1 - 1.2e-30 105.5 0.0 2.4e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 CCU97719.1 - 0.0053 16.5 0.1 0.22 11.2 0.0 2.9 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 CCU97719.1 - 0.019 15.3 0.0 3.1 8.3 0.0 2.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 CCU97719.1 - 0.033 13.1 0.0 0.071 12.0 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase Abhydrolase_5 PF12695.2 CCU97720.1 - 0.0031 17.2 0.0 0.01 15.6 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCU97720.1 - 0.36 10.6 9.5 12 5.6 6.5 2.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L1 PF00687.16 CCU97721.1 - 3.5e-58 196.5 0.0 4.6e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Herpes_V23 PF01802.12 CCU97721.1 - 0.0018 17.3 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus VP23 like capsid protein Pyr_redox PF00070.22 CCU97722.1 - 3.2e-15 56.2 0.0 7.4e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCU97722.1 - 9.6e-06 25.6 0.0 0.0012 18.7 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCU97722.1 - 0.047 12.6 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 CCU97722.1 - 0.055 13.5 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCU97722.1 - 0.21 10.0 0.0 6.1 5.2 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein 3-HAO PF06052.7 CCU97724.1 - 7.2e-32 109.8 0.1 7.9e-32 109.7 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 CCU97724.1 - 0.00065 19.1 0.0 0.00093 18.6 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 CCU97724.1 - 0.00096 18.6 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Cupin LSM PF01423.17 CCU97725.1 - 4.7e-17 61.2 0.9 5.5e-17 61.0 0.6 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 CCU97726.1 - 5.1e-07 29.3 0.0 2e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CCU97726.1 - 0.015 15.0 0.1 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L5 PyrBI_leader PF08052.6 CCU97726.1 - 0.083 12.7 0.1 0.3 10.9 0.1 1.9 1 0 0 1 1 1 0 PyrBI operon leader peptide adh_short PF00106.20 CCU97727.1 - 5.6e-20 71.9 0.1 5.6e-20 71.9 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCU97727.1 - 6.7e-10 38.9 0.1 1e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCU97727.1 - 2.8e-08 33.8 0.2 4.9e-08 33.0 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCU97727.1 - 0.0007 19.1 1.8 0.0026 17.2 1.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.10 CCU97727.1 - 0.034 13.7 0.5 0.091 12.3 0.4 1.8 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.10 CCU97727.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein VanW PF04294.8 CCU97727.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 VanW like protein Eno-Rase_NADH_b PF12242.3 CCU97727.1 - 0.15 11.8 0.4 0.42 10.4 0.3 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CCU97727.1 - 0.16 11.9 3.5 1 9.3 2.5 2.4 1 1 0 1 1 1 0 NADH(P)-binding Clathrin PF00637.15 CCU97728.1 - 2e-16 59.8 0.1 6.2e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 CCU97728.1 - 8.8e-05 22.2 0.4 0.056 13.3 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Pep3_Vps18 PF05131.9 CCU97728.1 - 0.063 12.7 0.0 1.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Pep3/Vps18/deep orange family zf-RING_2 PF13639.1 CCU97728.1 - 0.4 10.5 4.5 0.8 9.5 0.9 2.4 2 0 0 2 2 2 0 Ring finger domain GRIM-19 PF06212.7 CCU97729.1 - 4.7e-30 103.9 0.0 5.4e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Nop14 PF04147.7 CCU97730.1 - 1e-217 725.0 31.5 1.2e-217 724.8 21.8 1.0 1 0 0 1 1 1 1 Nop14-like family 14-3-3 PF00244.15 CCU97732.1 - 1.9e-117 390.4 6.0 2.2e-117 390.2 4.1 1.0 1 0 0 1 1 1 1 14-3-3 protein Adaptin_N PF01602.15 CCU97733.1 - 4.2e-97 325.6 0.8 5.1e-97 325.3 0.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 CCU97733.1 - 2e-20 72.8 0.0 3.5e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain HEAT PF02985.17 CCU97733.1 - 0.0019 18.1 4.7 1.8 8.8 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat RasGEF_N_2 PF14663.1 CCU97733.1 - 0.023 14.6 6.5 0.04 13.8 0.2 3.8 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_2 PF13646.1 CCU97733.1 - 0.072 13.3 14.5 0.045 14.0 0.8 3.9 4 1 0 4 4 4 0 HEAT repeats RRN3 PF05327.6 CCU97734.1 - 3e-104 349.1 0.0 4e-104 348.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Ras PF00071.17 CCU97735.1 - 1.5e-45 154.5 0.0 1.8e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU97735.1 - 1e-10 42.1 0.0 1.9e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCU97735.1 - 2.1e-06 27.0 0.0 3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCU97735.1 - 0.003 16.7 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region STAS PF01740.16 CCU97735.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.5 1 1 0 1 1 1 0 STAS domain SHS2_Rpb7-N PF03876.12 CCU97736.1 - 1.1e-07 31.8 0.0 2.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Thioredoxin PF00085.15 CCU97737.1 - 2.1e-27 94.7 0.0 2.7e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CCU97737.1 - 1.1e-11 44.8 0.1 6.8e-11 42.3 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCU97737.1 - 1.5e-07 31.3 0.0 2.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CCU97737.1 - 1.5e-05 24.8 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CCU97737.1 - 4.8e-05 22.9 0.0 6.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 CCU97737.1 - 9.8e-05 21.9 0.2 0.0077 15.7 0.0 2.1 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 CCU97737.1 - 0.0018 17.9 0.0 0.0031 17.1 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.1 CCU97737.1 - 0.006 16.3 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Glutaredoxin PF00462.19 CCU97737.1 - 0.015 15.2 0.2 0.062 13.2 0.1 2.0 1 1 0 1 1 1 0 Glutaredoxin DUF836 PF05768.9 CCU97737.1 - 0.018 15.2 0.0 0.09 13.0 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) HyaE PF07449.6 CCU97737.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE FAM86 PF14904.1 CCU97737.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function Methyltransf_16 PF10294.4 CCU97738.1 - 6.9e-15 54.9 0.0 1.9e-11 43.7 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase RasGAP PF00616.14 CCU97738.1 - 2.3e-07 30.6 0.0 4.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase MTS PF05175.9 CCU97738.1 - 5.8e-05 22.5 0.1 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CCU97738.1 - 0.00031 21.2 0.0 0.0019 18.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain CRAL_TRIO_2 PF13716.1 CCU97738.1 - 0.028 14.3 0.0 0.08 12.8 0.0 1.8 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Methyltransf_31 PF13847.1 CCU97738.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Flu_NS1 PF00600.14 CCU97738.1 - 0.17 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) MT-A70 PF05063.9 CCU97739.1 - 1.6e-52 177.6 0.0 2.8e-52 176.8 0.0 1.4 1 1 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 CCU97739.1 - 0.056 13.4 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SCP2 PF02036.12 CCU97741.1 - 1.7e-23 82.8 1.2 2e-23 82.6 0.8 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 CCU97741.1 - 0.0056 16.6 0.5 0.0068 16.3 0.4 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Peptidase_S3 PF00944.14 CCU97741.1 - 0.14 11.6 0.5 0.25 10.7 0.1 1.6 2 0 0 2 2 2 0 Alphavirus core protein Bot1p PF12298.3 CCU97742.1 - 1.2e-22 80.6 0.0 1.6e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 CCU97742.1 - 0.00037 20.4 0.1 0.00037 20.4 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 UPF0240 PF06784.6 CCU97742.1 - 0.04 13.5 0.2 0.86 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) His_Phos_2 PF00328.17 CCU97743.1 - 4.8e-71 239.8 0.1 8e-71 239.1 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CCU97743.1 - 5.9e-07 29.1 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CCU97743.1 - 0.16 11.8 0.0 0.63 9.8 0.0 2.0 1 1 0 1 1 1 0 ATP-grasp domain LETM1 PF07766.8 CCU97744.1 - 5e-11 42.1 7.2 1.8e-08 33.7 0.4 2.3 1 1 1 2 2 2 2 LETM1-like protein LSM PF01423.17 CCU97745.1 - 0.012 15.1 0.1 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 LSM domain QueC PF06508.8 CCU97748.1 - 0.021 14.1 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Pex24p PF06398.6 CCU97749.1 - 2.2e-27 95.8 2.5 5.5e-27 94.5 1.8 1.6 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Spt20 PF12090.3 CCU97750.1 - 2e-28 98.9 0.0 4.9e-28 97.7 0.0 1.6 2 0 0 2 2 2 1 Spt20 family PINIT PF14324.1 CCU97751.1 - 1.2e-31 109.7 0.0 2e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 CCU97751.1 - 5.5e-19 67.4 6.1 9.4e-19 66.6 4.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CCU97751.1 - 7.6e-07 28.5 1.3 1.4e-06 27.6 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 CCU97751.1 - 0.014 14.8 4.0 0.97 9.0 0.0 3.6 4 0 0 4 4 4 0 SAP domain zf-C3HC4_4 PF15227.1 CCU97751.1 - 0.93 9.4 5.1 1.9 8.4 3.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CCU97751.1 - 2.3 8.1 5.7 4.5 7.1 4.0 1.5 1 0 0 1 1 1 0 Ring finger domain MgsA_C PF12002.3 CCU97752.1 - 3.6e-47 160.1 0.1 3.2e-46 157.0 0.0 2.0 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 CCU97752.1 - 4.9e-15 55.9 0.0 8.1e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCU97752.1 - 1.6e-14 53.5 0.0 4.2e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCU97752.1 - 5.7e-08 32.9 1.2 0.001 19.0 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CCU97752.1 - 1.2e-07 31.5 0.0 2.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCU97752.1 - 2.2e-07 31.0 0.3 8.2e-06 25.9 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCU97752.1 - 8.2e-07 28.9 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CCU97752.1 - 4.2e-06 26.0 0.3 0.062 12.4 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCU97752.1 - 4.3e-05 23.0 0.0 0.014 14.8 0.1 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_2 PF07724.9 CCU97752.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 CCU97752.1 - 0.00014 21.5 1.0 0.00032 20.3 0.1 2.1 2 0 0 2 2 1 1 Part of AAA domain Sigma54_activ_2 PF14532.1 CCU97752.1 - 0.00014 21.8 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 CCU97752.1 - 0.00082 19.2 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CCU97752.1 - 0.0017 18.0 0.0 0.0048 16.5 0.0 1.8 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 CCU97752.1 - 0.003 16.4 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain IstB_IS21 PF01695.12 CCU97752.1 - 0.0047 16.3 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 CCU97752.1 - 0.0051 16.3 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 CCU97752.1 - 0.0054 17.5 0.0 0.011 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CCU97752.1 - 0.0062 15.4 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 CCU97752.1 - 0.0066 16.7 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.1 CCU97752.1 - 0.0085 15.7 0.0 0.045 13.4 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Arch_ATPase PF01637.13 CCU97752.1 - 0.014 15.1 0.2 1.5 8.5 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 CCU97752.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CCU97752.1 - 0.022 14.4 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.2 CCU97752.1 - 0.022 14.2 0.1 0.2 11.0 0.0 2.1 1 1 1 2 2 2 0 AAA-like domain ABC_tran PF00005.22 CCU97752.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter TIP49 PF06068.8 CCU97752.1 - 0.037 12.7 0.0 0.076 11.7 0.0 1.5 1 1 1 2 2 2 0 TIP49 C-terminus AAA_25 PF13481.1 CCU97752.1 - 0.039 13.3 2.5 0.39 10.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 CCU97752.1 - 0.039 13.3 0.0 0.081 12.3 0.0 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 CCU97752.1 - 0.053 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 CCU97752.1 - 0.073 12.6 0.2 0.17 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 CCU97752.1 - 0.075 11.9 0.0 0.15 10.9 0.0 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 CCU97752.1 - 0.076 13.1 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 CCU97752.1 - 0.081 12.4 0.2 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.1 CCU97752.1 - 0.12 11.9 0.3 0.98 8.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain DUF543 PF04418.7 CCU97753.1 - 9.4e-28 95.9 0.3 1.6e-27 95.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Apolipoprotein PF01442.13 CCU97753.1 - 0.0026 17.2 1.3 0.0037 16.8 0.9 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 CCU97753.1 - 0.0042 17.4 4.6 1.8 9.0 0.5 3.1 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF883) Phage_GPO PF05929.6 CCU97753.1 - 0.024 13.8 1.9 0.032 13.5 1.3 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2277 PF10041.4 CCU97753.1 - 0.054 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) DUF2959 PF11172.3 CCU97753.1 - 0.18 11.5 2.0 0.24 11.1 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) CsbD PF05532.7 CCU97753.1 - 0.35 10.5 4.4 9.3 6.0 0.0 2.4 2 0 0 2 2 2 0 CsbD-like DUF4337 PF14235.1 CCU97753.1 - 2.4 7.9 4.7 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) YtxH PF12732.2 CCU97753.1 - 9.4 6.6 10.4 2.2 8.6 3.4 2.5 2 1 0 2 2 2 0 YtxH-like protein zf-CpG_bind_C PF12269.3 CCU97754.1 - 2.9e-06 26.9 0.1 7.1e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain Pkinase PF00069.20 CCU97755.1 - 1.5e-32 112.7 0.0 2.2e-31 108.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97755.1 - 5.2e-16 58.4 0.0 3.8e-08 32.7 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCU97755.1 - 6.8e-06 25.2 0.0 0.0003 19.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like PEX11 PF05648.9 CCU97756.1 - 1.3e-19 70.3 0.0 1.6e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Ribosomal_S17 PF00366.15 CCU97757.1 - 1.3e-16 60.4 1.1 2.5e-16 59.4 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Zds_C PF08632.5 CCU97758.1 - 4.8e-17 61.0 0.2 1.1e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Smr PF01713.16 CCU97759.1 - 1.6e-10 40.9 0.2 6.7e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Smr domain CUE PF02845.11 CCU97759.1 - 0.012 15.0 0.0 1.7 8.2 0.0 3.2 3 0 0 3 3 3 0 CUE domain DMA PF03474.9 CCU97759.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif DUF1771 PF08590.5 CCU97759.1 - 4.3 7.4 18.6 0.19 11.7 7.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) MFS_1 PF07690.11 CCU97760.1 - 2.1e-42 145.0 69.2 8.5e-21 74.0 20.3 3.4 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 CCU97760.1 - 8.7e-39 133.3 53.3 7.5e-19 67.6 4.6 4.5 4 1 0 4 4 4 4 Sugar (and other) transporter Urb2 PF10441.4 CCU97761.1 - 2.9e-33 115.3 0.0 1.9e-32 112.7 0.0 2.3 2 0 0 2 2 2 1 Urb2/Npa2 family Ribosomal_L36 PF00444.13 CCU97762.1 - 2.2e-17 62.7 9.8 3.4e-17 62.1 6.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 DUF3049 PF11250.3 CCU97762.1 - 0.019 14.7 0.6 0.049 13.3 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3049) NTP_transferase PF00483.18 CCU97763.1 - 1.7e-42 145.4 0.0 2.5e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CCU97763.1 - 1.5e-08 34.8 1.2 2.3e-08 34.2 0.1 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.13 CCU97763.1 - 7.4e-07 28.8 0.1 1.7e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase IspD PF01128.14 CCU97763.1 - 0.0028 17.2 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NIR_SIR PF01077.17 CCU97765.1 - 5.5e-48 162.2 0.0 2.6e-39 134.0 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.20 CCU97765.1 - 8.2e-27 93.9 0.0 1.5e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.12 CCU97765.1 - 2.4e-26 91.1 0.0 3.5e-12 45.7 0.0 3.0 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.14 CCU97765.1 - 2.7e-09 36.8 0.5 6.1e-09 35.7 0.4 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg TPR_6 PF13174.1 CCU97765.1 - 0.024 15.1 1.4 4 8.1 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCU97765.1 - 0.11 12.4 1.2 3.6 7.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat YwhD PF08741.5 CCU97765.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 YwhD family HtaA PF04213.8 CCU97765.1 - 0.13 12.4 0.1 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Htaa RNB PF00773.14 CCU97766.1 - 2.5e-89 299.7 0.0 3.3e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 CCU97766.1 - 2.6e-10 40.5 0.4 8.2e-10 38.9 0.3 1.9 1 1 0 1 1 1 1 PIN domain DUF1953 PF09196.5 CCU97766.1 - 0.051 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) NDK PF00334.14 CCU97767.1 - 4.2e-52 175.5 0.0 5.4e-52 175.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Sin_N PF04801.8 CCU97768.1 - 4.8e-24 84.9 0.0 6.2e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region TAFII55_N PF04658.8 CCU97769.1 - 7.7e-52 175.0 0.1 7.7e-52 175.0 0.0 1.5 2 0 0 2 2 2 1 TAFII55 protein conserved region DUF1741 PF08427.5 CCU97770.1 - 2.7e-25 89.2 0.0 5.3e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Cation_efflux PF01545.16 CCU97771.1 - 4.5e-78 262.2 5.4 6.1e-78 261.7 3.7 1.1 1 0 0 1 1 1 1 Cation efflux family RAI1 PF08652.6 CCU97772.1 - 1.8e-15 56.4 0.0 3.7e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease GTP_EFTU PF00009.22 CCU97773.1 - 5.6e-57 192.2 0.1 8.2e-57 191.6 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCU97773.1 - 2.2e-36 123.9 0.0 5.2e-36 122.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCU97773.1 - 1.3e-17 63.6 0.5 3.7e-17 62.2 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCU97773.1 - 4.6e-05 22.9 0.1 0.00013 21.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCU97773.1 - 0.0033 17.3 0.2 0.011 15.6 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase 5HT_transporter PF03491.8 CCU97773.1 - 0.02 15.0 0.4 0.083 13.0 0.0 2.2 3 0 0 3 3 3 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus WH2 PF02205.15 CCU97774.1 - 0.00087 18.8 0.1 0.0023 17.4 0.0 1.8 1 0 0 1 1 1 1 WH2 motif UQ_con PF00179.21 CCU97775.1 - 2.6e-46 156.5 0.0 3e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCU97775.1 - 9.1e-06 25.4 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CCU97775.1 - 0.0027 17.3 0.0 0.0051 16.4 0.0 1.6 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 CCU97775.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain DUF2841 PF11001.3 CCU97776.1 - 4.4e-38 129.9 0.1 7.6e-38 129.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) His_Phos_1 PF00300.17 CCU97777.1 - 5.9e-40 136.9 0.0 7e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DNA_pol_B PF00136.16 CCU97778.1 - 3.8e-79 266.6 0.0 5.1e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CCU97778.1 - 5.2e-22 78.1 0.0 3.2e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CCU97778.1 - 7.5e-09 35.4 5.6 1.4e-08 34.5 3.8 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 CCU97778.1 - 0.84 8.2 0.1 1.3 7.5 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral HEAT PF02985.17 CCU97779.1 - 1.3e-39 130.7 25.4 0.00096 19.0 0.0 13.0 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.1 CCU97779.1 - 2.2e-31 107.9 28.1 1.9e-07 31.2 0.0 7.6 1 1 7 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.2 CCU97779.1 - 2.7e-13 50.0 1.7 0.00036 20.8 0.0 7.5 4 2 5 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CCU97779.1 - 7.3e-13 48.5 31.8 0.0047 17.3 0.1 9.8 7 3 3 10 10 10 5 HEAT-like repeat Adaptin_N PF01602.15 CCU97779.1 - 2.7e-09 35.8 10.9 2e-07 29.7 2.4 3.7 2 1 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 CCU97779.1 - 5e-08 32.5 2.6 0.013 14.9 0.0 4.7 2 2 3 5 5 5 2 CLASP N terminal Cnd1 PF12717.2 CCU97779.1 - 0.0038 17.1 2.7 1.1 9.1 0.0 4.6 2 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CCU97779.1 - 0.0056 16.4 9.7 5.8 6.8 0.0 6.9 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 CCU97779.1 - 0.011 15.6 5.1 3.7 7.5 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2435) CRAL_TRIO PF00650.15 CCU97780.1 - 4.9e-26 91.1 0.0 7.1e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CCU97780.1 - 3.2e-07 30.3 0.0 4.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SURF4 PF02077.10 CCU97781.1 - 3.7e-95 318.3 8.3 4.2e-95 318.1 5.8 1.0 1 0 0 1 1 1 1 SURF4 family DUF619 PF04768.8 CCU97782.1 - 6.4e-41 139.6 0.0 1.6e-40 138.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 CCU97782.1 - 3.9e-25 88.4 0.2 1.1e-24 87.0 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 CCU97782.1 - 1.8e-23 83.3 0.0 3.1e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 CCU97782.1 - 9.3e-12 45.1 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 CCU97782.1 - 0.036 13.9 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pam16 PF03656.8 CCU97782.1 - 0.043 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Pam16 Pkinase PF00069.20 CCU97785.1 - 1.5e-67 227.4 0.0 1.9e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97785.1 - 9.6e-46 155.9 0.0 1.3e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU97785.1 - 2e-05 23.7 0.0 3.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCU97785.1 - 0.0023 17.0 0.2 0.0047 16.0 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCU97785.1 - 0.013 15.2 0.3 0.48 10.1 0.2 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Peptidase_M24 PF00557.19 CCU97786.1 - 7.1e-40 136.8 0.0 1.1e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CCU97786.1 - 4.4e-22 78.9 0.2 8.7e-20 71.5 0.0 3.0 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain AdoHcyase PF05221.12 CCU97787.1 - 2.1e-141 469.5 0.0 2.4e-141 469.3 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CCU97787.1 - 8.8e-84 279.2 1.9 1.3e-83 278.6 1.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CCU97787.1 - 9.9e-10 37.8 0.2 2.4e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CCU97787.1 - 0.00028 20.2 0.2 0.00044 19.6 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CCU97787.1 - 0.0012 18.8 0.1 0.0031 17.4 0.0 1.8 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 CCU97787.1 - 0.015 14.9 0.2 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 CCU97787.1 - 0.049 13.7 0.2 0.096 12.7 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TMEM107 PF14995.1 CCU97787.1 - 0.07 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein NAD_binding_7 PF13241.1 CCU97787.1 - 0.088 13.0 0.1 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding PPR_2 PF13041.1 CCU97788.1 - 0.021 14.8 0.0 3.8 7.5 0.0 3.3 3 0 0 3 3 3 0 PPR repeat family EF-hand_1 PF00036.27 CCU97789.1 - 1e-24 83.8 8.8 5.6e-09 34.6 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CCU97789.1 - 3.1e-23 81.6 7.9 1.5e-13 50.6 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCU97789.1 - 5.4e-21 72.5 8.9 9.7e-09 34.3 0.1 4.0 4 2 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CCU97789.1 - 5.5e-17 61.1 11.9 3.4e-10 39.3 1.3 3.6 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CCU97789.1 - 4.7e-16 57.3 8.2 2.1e-05 23.6 0.1 3.8 3 1 1 4 4 4 3 EF hand EF-hand_9 PF14658.1 CCU97789.1 - 3.3e-10 39.7 0.3 5.2e-05 23.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CCU97789.1 - 7.3e-08 32.0 2.8 0.00012 21.7 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 CCU97789.1 - 0.003 17.1 0.1 0.068 12.7 0.0 2.4 2 1 1 3 3 3 1 Caleosin related protein DUF3164 PF11363.3 CCU97789.1 - 0.0081 15.5 0.2 3.9 6.8 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF3164) SPARC_Ca_bdg PF10591.4 CCU97789.1 - 0.055 13.4 0.5 7.1 6.6 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MgtE_N PF03448.12 CCU97789.1 - 0.31 11.3 5.1 0.21 11.9 0.6 2.3 3 0 0 3 3 3 0 MgtE intracellular N domain TerB PF05099.8 CCU97789.1 - 0.51 10.0 3.2 6.3 6.5 0.2 2.6 1 1 2 3 3 3 0 Tellurite resistance protein TerB TFIIA_gamma_N PF02268.11 CCU97790.1 - 2.6e-26 90.9 0.1 3.6e-26 90.5 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 CCU97790.1 - 2.3e-23 81.7 0.0 3.1e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Ctf8 PF09696.5 CCU97791.1 - 3e-15 56.0 0.2 1.4e-09 37.8 0.0 2.4 2 1 0 2 2 2 2 Ctf8 SMN PF06003.7 CCU97791.1 - 9 5.3 11.8 13 4.7 8.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) GalKase_gal_bdg PF10509.4 CCU97792.1 - 5.6e-19 67.1 0.1 1.1e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 CCU97792.1 - 2.5e-14 53.2 0.0 6.3e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 CCU97792.1 - 1.6e-09 37.6 0.3 1.6e-09 37.6 0.2 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF1845 PF08900.6 CCU97792.1 - 0.049 12.9 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) ArfGap PF01412.13 CCU97793.1 - 3.3e-29 101.0 0.0 4.5e-29 100.6 0.0 1.2 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf Cytochrom_C PF00034.16 CCU97793.1 - 0.11 13.3 0.4 0.15 12.9 0.3 1.3 1 0 0 1 1 1 0 Cytochrome c zf-dskA_traR PF01258.12 CCU97793.1 - 0.19 11.5 1.5 6.5 6.5 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Paired_CXXCH_1 PF09699.5 CCU97793.1 - 0.22 11.0 0.2 0.22 11.0 0.1 2.4 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-C2H2 PF00096.21 CCU97793.1 - 1.7 9.1 0.0 1.7 9.1 0.0 3.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type GATA PF00320.22 CCU97793.1 - 2.2 7.7 7.8 2.7 7.4 0.8 2.5 2 0 0 2 2 2 0 GATA zinc finger HCMV_UL139 PF12507.3 CCU97794.1 - 0.0016 18.6 2.3 0.0034 17.5 1.6 1.5 1 0 0 1 1 1 1 Human Cytomegalovirus UL139 protein Myb_DNA-bind_6 PF13921.1 CCU97794.1 - 0.064 13.3 2.4 0.065 13.3 0.5 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCU97794.1 - 0.08 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DFP PF04127.10 CCU97795.1 - 2.4e-20 72.9 0.0 7.5e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein zf-H2C2_2 PF13465.1 CCU97796.1 - 9.4e-09 35.1 0.6 9.4e-09 35.1 0.4 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 CCU97796.1 - 9.7e-07 28.7 17.5 2.9e-06 27.3 0.2 4.1 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCU97796.1 - 7e-05 22.8 10.2 0.00037 20.6 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCU97796.1 - 8.1e-05 22.3 2.6 0.33 10.9 0.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 CCU97796.1 - 0.084 13.1 6.0 3.7 7.8 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CCU97796.1 - 0.45 10.6 3.2 4.5 7.4 0.2 2.8 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CCU97796.1 - 2.3 8.4 0.0 2.3 8.4 0.0 3.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DnaJ PF00226.26 CCU97797.1 - 3.7e-15 55.3 0.2 7.8e-15 54.3 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Complex1_LYR PF05347.10 CCU97797.1 - 5.1e-07 29.3 0.0 5.1e-07 29.3 0.0 2.4 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCU97797.1 - 1.5e-05 25.1 0.8 1.5e-05 25.1 0.6 2.0 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CCU97797.1 - 0.15 12.5 4.0 7.2 7.1 0.2 2.4 1 1 1 2 2 2 0 Complex1_LYR-like DUF2404 PF10296.4 CCU97798.1 - 0.029 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) SPRY PF00622.23 CCU97799.1 - 7.5e-06 26.0 0.0 2.5e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 SPRY domain Gtr1_RagA PF04670.7 CCU97800.1 - 3.6e-40 137.5 0.2 1.2e-38 132.5 0.1 2.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SUI1 PF01253.17 CCU97800.1 - 0.00016 21.4 0.2 0.0007 19.3 0.1 1.9 1 1 0 1 1 1 1 Translation initiation factor SUI1 MMR_HSR1 PF01926.18 CCU97800.1 - 0.00062 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 CCU97800.1 - 0.0021 17.9 0.0 0.0055 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCU97800.1 - 0.0042 17.0 0.2 2.4 8.1 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Miro PF08477.8 CCU97800.1 - 0.011 16.2 0.0 0.053 14.0 0.0 2.2 1 1 0 1 1 1 0 Miro-like protein Cgr1 PF03879.9 CCU97800.1 - 0.024 14.8 9.3 0.04 14.0 6.4 1.2 1 0 0 1 1 1 0 Cgr1 family Arf PF00025.16 CCU97800.1 - 0.024 13.8 0.1 4.9 6.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Arch_ATPase PF01637.13 CCU97800.1 - 0.039 13.6 0.7 0.21 11.2 0.0 2.2 3 0 0 3 3 3 0 Archaeal ATPase Ras PF00071.17 CCU97800.1 - 0.059 12.7 0.1 0.49 9.7 0.1 2.2 1 1 0 1 1 1 0 Ras family Guanylate_kin PF00625.16 CCU97800.1 - 0.075 12.4 1.3 7.6 5.9 0.4 2.4 2 0 0 2 2 2 0 Guanylate kinase Ras PF00071.17 CCU97801.1 - 8e-45 152.1 0.0 1e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU97801.1 - 3.8e-09 37.0 0.0 7.3e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCU97801.1 - 4.9e-08 32.4 0.0 5.9e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCU97801.1 - 1.3e-05 24.6 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCU97801.1 - 0.017 14.2 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 CCU97801.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein EF_TS PF00889.14 CCU97802.1 - 2.5e-15 56.4 0.0 5.9e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor TS Nucleoporin_C PF03177.9 CCU97803.1 - 3.1e-68 230.7 2.3 4.8e-68 230.1 1.6 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CCU97803.1 - 1.5e-39 135.9 0.0 2e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like LCM PF04072.9 CCU97804.1 - 4.2e-10 39.4 0.1 1.1e-09 38.1 0.1 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Fcf1 PF04900.7 CCU97805.1 - 6.3e-22 77.5 0.0 1.2e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Fcf1 SE PF08491.5 CCU97806.1 - 1e-86 290.1 0.0 7e-86 287.4 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 CCU97806.1 - 2.4e-11 43.1 1.7 1.3e-05 24.3 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCU97806.1 - 1.2e-09 37.6 2.8 4.7e-07 29.1 0.3 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CCU97806.1 - 0.0016 18.3 0.9 0.0039 17.1 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCU97806.1 - 0.0023 17.0 0.4 0.0049 15.9 0.1 1.6 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 CCU97806.1 - 0.0044 15.9 0.1 0.22 10.3 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 CCU97806.1 - 0.0051 16.4 0.1 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 CCU97806.1 - 0.0076 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCU97806.1 - 0.011 16.1 0.6 0.024 15.0 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CCU97806.1 - 0.017 15.1 0.1 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 CCU97806.1 - 0.02 14.3 0.2 0.041 13.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDI PF00996.13 CCU97806.1 - 0.022 13.1 0.0 0.034 12.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor ThiF PF00899.16 CCU97806.1 - 0.037 13.8 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.7 CCU97806.1 - 0.047 12.6 0.9 0.31 9.9 0.4 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_2 PF03446.10 CCU97806.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 CCU97806.1 - 0.12 11.7 0.1 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.19 CCU97806.1 - 0.13 11.0 6.1 0.029 13.2 1.8 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 CCU97806.1 - 0.15 10.4 0.1 0.22 9.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 CCU97806.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 CCU97806.1 - 2.3 7.1 5.1 3.8 6.4 3.6 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase ATP-synt_J PF04911.7 CCU97807.1 - 8.5e-19 66.7 0.3 1.2e-18 66.2 0.2 1.2 1 0 0 1 1 1 1 ATP synthase j chain DUF3176 PF11374.3 CCU97807.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) AMP-binding PF00501.23 CCU97808.1 - 7.9e-63 212.2 0.0 1.5e-62 211.3 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Clathrin PF00637.15 CCU97809.1 - 1.4e-15 57.1 0.0 2.4e-12 46.6 0.0 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 CCU97809.1 - 0.00053 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 CCU97809.1 - 0.0036 17.0 6.4 0.0099 15.6 4.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCU97809.1 - 0.0048 16.6 4.6 0.012 15.3 3.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCU97809.1 - 0.0088 16.0 5.4 0.021 14.8 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCU97809.1 - 0.0098 15.9 1.2 0.029 14.4 0.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CCU97809.1 - 0.44 10.2 5.0 1 9.0 3.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pheromone PF08015.6 CCU97810.1 - 0.23 12.2 4.8 0.62 10.9 3.4 1.7 1 0 0 1 1 1 0 Fungal mating-type pheromone TT_ORF2 PF02957.10 CCU97810.1 - 0.3 11.7 1.3 0.5 11.0 0.9 1.3 1 0 0 1 1 1 0 TT viral ORF2 Ras PF00071.17 CCU97811.1 - 3.1e-40 137.2 1.0 3.6e-40 136.9 0.7 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU97811.1 - 8.5e-07 29.4 0.0 1.4e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCU97811.1 - 1.4e-06 27.6 0.4 1.8e-06 27.3 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Phage_C PF12025.3 CCU97811.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 Phage protein C GTP_EFTU PF00009.22 CCU97811.1 - 0.04 13.3 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ATP-synt_10 PF05176.9 CCU97812.1 - 3.2e-26 92.1 0.0 1.3e-17 63.9 0.0 3.1 1 1 2 3 3 3 2 ATP10 protein U3_assoc_6 PF08640.6 CCU97812.1 - 7.9e-17 60.8 2.7 7.9e-17 60.8 1.9 1.8 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 DNA_primase_lrg PF04104.9 CCU97813.1 - 2.6e-73 246.4 0.0 3.6e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit PIP5K PF01504.13 CCU97814.1 - 1.3e-80 270.1 0.0 3.1e-80 268.9 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase His_biosynth PF00977.16 CCU97816.1 - 2e-42 145.0 0.0 1.9e-24 86.1 0.1 3.2 2 2 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.23 CCU97816.1 - 3.8e-18 65.6 0.0 6.4e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CCU97816.1 - 5.7e-08 32.5 0.0 2.4e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 CCU97816.1 - 0.0001 21.9 0.0 0.051 13.2 0.0 2.5 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 CCU97816.1 - 0.078 12.4 0.1 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 PhoD PF09423.5 CCU97817.1 - 4.3e-37 127.7 0.0 2.9e-36 125.0 0.0 1.9 1 1 0 1 1 1 1 PhoD-like phosphatase DUF629 PF04780.7 CCU97817.1 - 0.047 12.2 0.0 0.07 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Ribosomal_S7 PF00177.16 CCU97818.1 - 3.7e-31 107.6 0.0 4.8e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Response_reg PF00072.19 CCU97819.1 - 2.1e-15 56.6 0.0 1.9e-14 53.5 0.0 2.2 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 CCU97819.1 - 6.4e-15 54.9 0.1 1.6e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain TFIIB PF00382.14 CCU97820.1 - 8.3e-30 102.4 6.2 4.4e-18 64.8 0.6 2.9 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CCU97820.1 - 1.4e-15 56.3 0.9 2.3e-15 55.6 0.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 CCU97820.1 - 0.0006 19.7 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 Cyclin, C-terminal domain RB_B PF01857.15 CCU97820.1 - 0.0073 15.8 0.0 0.016 14.7 0.0 1.5 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain Nudix_N_2 PF14803.1 CCU97820.1 - 1 9.0 3.2 28 4.5 0.0 3.4 3 0 0 3 3 3 0 Nudix N-terminal Nup84_Nup100 PF04121.8 CCU97821.1 - 1.7e-100 336.7 0.0 4.7e-99 331.9 0.0 2.0 1 1 1 2 2 2 2 Nuclear pore protein 84 / 107 Lipase_GDSL_2 PF13472.1 CCU97821.1 - 0.02 15.0 0.3 0.074 13.1 0.2 2.0 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family PPR_3 PF13812.1 CCU97821.1 - 0.025 14.8 1.1 6.5 7.3 0.1 3.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain SH3_1 PF00018.23 CCU97823.1 - 2.7e-11 42.6 0.0 5e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCU97823.1 - 5.2e-09 35.5 0.1 1.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCU97823.1 - 2.2e-08 33.4 0.0 5.1e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain FCH PF00611.18 CCU97824.1 - 3.6e-05 23.8 0.0 4.2e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Varsurf_PPLC PF03490.8 CCU97824.1 - 0.039 13.6 0.4 5.3 6.7 0.0 2.4 1 1 1 2 2 2 0 Variant-surface-glycoprotein phospholipase C PCNA_N PF00705.13 CCU97825.1 - 5e-50 168.2 1.5 2.7e-49 165.9 1.5 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CCU97825.1 - 7.4e-41 139.0 3.2 3.1e-22 78.8 0.0 2.8 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 CCU97825.1 - 8.5e-06 25.0 0.0 1.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 CCU97825.1 - 1.4e-05 23.9 0.9 0.0035 16.1 0.6 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 CCU97825.1 - 0.0067 15.4 0.0 0.14 11.0 0.0 2.1 1 1 1 2 2 2 1 Hus1-like protein RTA1 PF04479.8 CCU97826.1 - 3.2e-39 134.7 2.0 3.2e-39 134.7 1.4 1.4 2 0 0 2 2 2 1 RTA1 like protein SET PF00856.23 CCU97827.1 - 0.00053 20.3 0.3 0.08 13.2 0.0 3.1 3 0 0 3 3 3 2 SET domain Peptidase_S8 PF00082.17 CCU97828.1 - 1.5e-48 165.3 0.0 3.2e-48 164.2 0.0 1.6 1 1 0 1 1 1 1 Subtilase family TPPII PF12580.3 CCU97828.1 - 3.2e-37 127.7 0.0 4.6e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Tripeptidyl peptidase II POX PF07526.6 CCU97828.1 - 3.1 8.0 5.6 0.84 9.8 0.3 2.4 3 0 0 3 3 3 0 Associated with HOX GAS PF13851.1 CCU97828.1 - 3.5 6.7 4.7 6.1 5.9 3.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GDI PF00996.13 CCU97829.1 - 8.2e-54 182.5 0.0 1e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CCU97829.1 - 0.0089 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CCU97829.1 - 0.021 13.8 0.1 0.046 12.7 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Peptidase_S49 PF01343.13 CCU97830.1 - 2.3e-46 157.3 0.0 5.3e-29 100.9 0.1 3.2 3 0 0 3 3 3 2 Peptidase family S49 CLP_protease PF00574.18 CCU97830.1 - 0.0001 22.0 0.4 0.007 16.0 0.0 2.5 3 0 0 3 3 3 2 Clp protease DPBB_1 PF03330.13 CCU97831.1 - 2.6e-10 40.1 0.1 3.7e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CCU97831.1 - 0.034 13.7 0.1 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Barwin family TRAM_LAG1_CLN8 PF03798.11 CCU97832.1 - 4.6e-35 120.9 19.1 4.6e-35 120.9 13.2 2.2 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CCU97832.1 - 9.6e-06 25.0 0.0 9.6e-06 25.0 0.0 3.3 3 0 0 3 3 3 1 TRAM1-like protein Aldedh PF00171.17 CCU97833.1 - 9e-09 34.1 5.1 1.5e-07 30.1 3.6 2.2 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF3619 PF12279.3 CCU97833.1 - 0.22 11.6 2.9 0.64 10.1 2.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF3636 PF12331.3 CCU97834.1 - 0.29 10.7 2.9 5.2 6.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3636) XPG_N PF00752.12 CCU97835.1 - 1.5e-19 70.1 0.0 1.7e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 XPG N-terminal domain Peripla_BP_2 PF01497.13 CCU97835.1 - 0.077 12.1 0.0 0.096 11.8 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein XPG_I PF00867.13 CCU97836.1 - 6.7e-14 51.7 0.1 1.3e-13 50.7 0.1 1.6 1 1 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CCU97836.1 - 1.1e-07 31.9 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.6 CCU97836.1 - 0.0027 16.6 0.0 0.0049 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1552) HHH_5 PF14520.1 CCU97836.1 - 0.033 14.3 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain SKN1 PF03935.10 CCU97837.1 - 0 1141.4 19.1 1.2e-172 574.6 5.4 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) OppC_N PF12911.2 CCU97837.1 - 0.0023 17.2 1.2 1.7 8.0 0.0 2.8 3 0 0 3 3 3 2 N-terminal TM domain of oligopeptide transport permease C DUF2162 PF09930.4 CCU97837.1 - 0.016 14.3 0.0 3.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Predicted transporter (DUF2162) DUF4479 PF14794.1 CCU97837.1 - 0.12 11.9 0.7 0.23 11.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) zf-C2H2 PF00096.21 CCU97838.1 - 1.2e-12 47.3 15.8 1.6e-05 24.9 0.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCU97838.1 - 2.5e-11 43.0 17.6 0.00057 20.0 0.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCU97838.1 - 7e-05 22.9 14.8 0.073 13.3 0.2 4.5 4 1 0 4 4 4 3 Zinc-finger double domain zinc_ribbon_5 PF13719.1 CCU97838.1 - 0.039 13.5 3.1 3.2 7.4 0.6 2.6 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CCU97838.1 - 0.082 12.6 3.5 4 7.2 0.6 2.7 2 1 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.8 CCU97838.1 - 0.16 11.7 2.7 0.33 10.6 0.3 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2HC_2 PF13913.1 CCU97838.1 - 0.29 10.8 15.6 0.17 11.5 0.7 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 CCU97838.1 - 0.69 10.1 6.8 4.3 7.6 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF1610 PF07754.6 CCU97838.1 - 2.5 8.3 10.4 12 6.1 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-C2H2_6 PF13912.1 CCU97838.1 - 2.6 8.0 6.6 6.4 6.8 1.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger SET PF00856.23 CCU97839.1 - 1.5e-05 25.3 0.0 2.2e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 SET domain Steroid_dh PF02544.11 CCU97840.1 - 1.2e-38 132.2 0.2 1.2e-38 132.2 0.1 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CCU97840.1 - 0.0001 21.7 0.2 0.00021 20.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CCU97840.1 - 0.00041 20.4 0.9 0.00081 19.4 0.2 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 CCU97840.1 - 0.0063 16.6 0.2 0.02 15.0 0.1 1.9 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ubiquitin PF00240.18 CCU97840.1 - 0.043 13.2 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Skp1_POZ PF03931.10 CCU97842.1 - 8.7e-08 32.1 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DsrD PF08679.6 CCU97842.1 - 0.014 15.3 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) ATP-synt_C PF00137.16 CCU97843.1 - 6e-23 80.5 14.4 2e-11 43.6 3.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.19 CCU97843.1 - 0.049 13.2 2.2 0.18 11.4 1.5 1.8 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Peptidase_C13 PF01650.13 CCU97844.1 - 6.2e-47 160.0 0.0 7.4e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family DS PF01916.12 CCU97845.1 - 5.5e-130 432.8 0.0 1e-129 431.9 0.0 1.4 2 0 0 2 2 2 1 Deoxyhypusine synthase ThiF PF00899.16 CCU97845.1 - 7.8e-38 129.3 0.1 2.1e-37 127.9 0.0 1.7 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 CCU97845.1 - 3.4e-23 80.9 0.6 6.9e-23 79.9 0.4 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCU97845.1 - 3.7e-18 64.6 1.7 7.3e-18 63.6 1.2 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 CCU97845.1 - 0.0011 18.5 0.5 0.0034 16.9 0.0 2.0 2 0 0 2 2 2 1 MoeZ/MoeB domain PIG-S PF10510.4 CCU97845.1 - 0.043 12.4 0.1 0.06 12.0 0.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Shikimate_DH PF01488.15 CCU97845.1 - 0.11 12.6 0.2 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.3 CCU97845.1 - 0.29 11.0 2.1 0.57 10.0 1.5 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein G-patch PF01585.18 CCU97847.1 - 5.7e-13 48.4 1.1 1.5e-12 47.1 0.7 1.8 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 CCU97847.1 - 8.4e-12 44.6 0.0 2.1e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 CCU97847.1 - 2.6e-06 27.1 0.6 2.6e-06 27.1 0.4 3.0 3 0 0 3 3 3 1 DExH-box splicing factor binding site DUF4519 PF15012.1 CCU97847.1 - 0.14 12.0 4.3 0.37 10.7 3.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) SIR2 PF02146.12 CCU97848.1 - 9.7e-51 172.0 0.0 1.5e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 CCU97848.1 - 1.5e-06 27.8 0.1 8.4e-06 25.4 0.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF592) CutC PF03932.9 CCU97848.1 - 0.014 14.6 0.0 0.056 12.6 0.0 1.8 2 0 0 2 2 2 0 CutC family DUF1769 PF08588.5 CCU97849.1 - 1.9e-16 59.7 0.4 3.6e-16 58.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) SURF6 PF04935.7 CCU97850.1 - 1.1e-26 93.5 20.2 1.2e-26 93.3 14.0 1.0 1 0 0 1 1 1 1 Surfeit locus protein 6 PLRV_ORF5 PF01690.12 CCU97850.1 - 0.54 9.3 10.5 0.62 9.1 7.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SpoVR PF04293.8 CCU97850.1 - 2 6.6 7.6 1.9 6.7 4.8 1.3 1 1 0 1 1 1 0 SpoVR like protein DUF4463 PF14703.1 CCU97850.1 - 3.5 8.2 10.2 0.62 10.6 4.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) CENP-Q PF13094.1 CCU97850.1 - 4 7.4 18.0 1 9.3 7.3 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ScpA_ScpB PF02616.9 CCU97850.1 - 4.3 6.8 8.8 5.3 6.5 6.1 1.1 1 0 0 1 1 1 0 ScpA/B protein WD40 PF00400.27 CCU97851.1 - 1.3e-90 294.3 20.8 1e-13 50.5 0.2 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 CCU97851.1 - 3.4e-07 30.1 0.0 6.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 CCU97851.1 - 0.00012 21.8 0.0 0.0088 15.7 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCU97851.1 - 0.00026 19.3 8.7 0.091 10.8 0.1 4.4 3 1 1 5 5 5 3 Nucleoporin Nup120/160 IKI3 PF04762.7 CCU97851.1 - 0.00027 18.9 2.1 0.0019 16.1 0.1 2.1 2 0 0 2 2 2 1 IKI3 family Nbas_N PF15492.1 CCU97851.1 - 0.0014 17.8 0.1 1.3 8.0 0.0 3.3 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 CCU97851.1 - 0.013 14.2 0.9 1.5 7.4 0.0 3.2 2 1 1 3 3 3 0 Nup133 N terminal like UQ_con PF00179.21 CCU97852.1 - 1.3e-22 79.7 0.0 4.3e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme BRO1 PF03097.13 CCU97854.1 - 1.5e-58 198.3 0.0 3e-58 197.4 0.0 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CCU97854.1 - 1.9e-23 82.8 4.2 6.4e-23 81.1 2.9 1.8 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV MAGSP PF03082.9 CCU97854.1 - 0.081 12.3 0.2 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Male accessory gland secretory protein WGG PF10273.4 CCU97855.1 - 3.7e-19 68.5 0.0 5.9e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF3425 PF11905.3 CCU97855.1 - 0.063 13.1 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) adh_short PF00106.20 CCU97856.1 - 7.2e-32 110.5 5.3 9.3e-32 110.2 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCU97856.1 - 1.2e-12 47.9 2.3 1.6e-12 47.5 1.6 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCU97856.1 - 1.4e-12 47.8 0.1 1.8e-12 47.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCU97856.1 - 0.00024 21.1 4.0 0.0033 17.4 2.7 2.3 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CCU97856.1 - 0.00024 20.8 0.6 0.00057 19.6 0.4 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CCU97856.1 - 0.0019 17.6 0.6 0.003 17.0 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 CCU97856.1 - 0.011 15.4 0.2 0.021 14.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CCU97856.1 - 0.012 14.7 0.1 0.029 13.4 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 CCU97856.1 - 0.075 12.1 0.1 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain COG4 PF08318.7 CCU97857.1 - 2.3e-17 62.7 0.0 5.3e-17 61.5 0.0 1.5 1 1 0 1 1 1 1 COG4 transport protein Snf7 PF03357.16 CCU97858.1 - 0.13 11.5 0.4 0.49 9.7 0.1 1.9 2 0 0 2 2 2 0 Snf7 APS_kinase PF01583.15 CCU97859.1 - 6.1e-65 217.6 0.0 1.5e-64 216.3 0.0 1.5 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 CCU97859.1 - 2e-06 27.7 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCU97859.1 - 7.6e-06 26.2 0.1 1.9e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCU97859.1 - 1.2e-05 26.0 0.0 2.1e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CCU97859.1 - 0.00047 19.6 0.1 0.00083 18.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.5 CCU97859.1 - 0.0007 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 CCU97859.1 - 0.0026 16.8 0.0 0.0058 15.7 0.0 1.8 1 1 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 CCU97859.1 - 0.03 14.6 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 CCU97859.1 - 0.087 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 CCU97859.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.1 CCU97859.1 - 0.12 12.3 0.1 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.13 CCU97859.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA PF00004.24 CCU97863.1 - 6.9e-96 317.5 0.0 1.4e-46 157.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CCU97863.1 - 3.4e-16 58.9 0.2 1.5e-15 56.9 0.1 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 CCU97863.1 - 2.1e-13 49.8 0.0 2e-05 23.7 0.0 3.1 2 2 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CCU97863.1 - 1.1e-12 48.0 0.0 2.1e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 CCU97863.1 - 1.8e-12 47.4 0.0 2.5e-07 30.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCU97863.1 - 4.2e-12 45.9 0.5 8.1e-06 25.6 0.1 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCU97863.1 - 4.9e-11 42.8 1.4 0.0022 18.1 0.1 4.3 3 2 1 4 4 2 2 AAA domain AAA_17 PF13207.1 CCU97863.1 - 5.5e-11 43.3 0.0 0.00053 20.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 CCU97863.1 - 6.1e-11 41.8 0.0 1.3e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 CCU97863.1 - 5.1e-10 39.6 0.0 0.00096 19.1 0.0 3.4 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 CCU97863.1 - 3e-09 36.0 0.0 0.0011 17.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 CCU97863.1 - 9.4e-09 34.9 0.0 0.001 18.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 CCU97863.1 - 1.1e-08 34.7 4.5 0.0044 16.4 0.0 4.7 3 2 2 5 5 5 2 AAA domain AAA_19 PF13245.1 CCU97863.1 - 6.6e-08 32.1 1.5 0.0027 17.4 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 CCU97863.1 - 6.7e-08 31.8 0.0 0.0051 15.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 CCU97863.1 - 7.6e-08 32.3 0.0 0.0029 17.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 CCU97863.1 - 3.6e-07 29.5 0.4 0.022 13.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CCU97863.1 - 1.2e-06 28.6 0.0 0.019 15.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 CCU97863.1 - 1.6e-06 27.4 1.0 0.47 9.5 0.0 3.5 2 1 1 3 3 3 2 KaiC Parvo_NS1 PF01057.12 CCU97863.1 - 4e-06 25.8 0.1 0.0045 15.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 CCU97863.1 - 4.6e-06 26.9 0.0 0.061 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CCU97863.1 - 5.1e-06 26.8 0.0 0.041 14.1 0.0 3.3 2 1 0 2 2 2 1 ABC transporter AAA_28 PF13521.1 CCU97863.1 - 5.7e-06 26.3 0.0 0.14 12.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 CCU97863.1 - 7.7e-06 25.8 0.0 0.0068 16.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Vps4_C PF09336.5 CCU97863.1 - 1.3e-05 24.9 0.1 7.6e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.21 CCU97863.1 - 1.4e-05 24.6 0.0 0.3 10.5 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 CCU97863.1 - 1.7e-05 24.8 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 CCU97863.1 - 1.8e-05 24.0 0.1 0.17 11.0 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 CCU97863.1 - 2.2e-05 24.1 0.0 0.1 12.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.8 CCU97863.1 - 4.7e-05 22.4 0.0 0.021 13.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 CCU97863.1 - 0.00011 21.8 0.2 0.49 10.0 0.0 3.7 3 0 0 3 3 3 1 NACHT domain AAA_11 PF13086.1 CCU97863.1 - 0.0002 20.9 0.0 0.43 10.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CCU97863.1 - 0.00022 21.0 0.0 2.4 7.7 0.0 3.3 2 1 1 3 3 3 1 Archaeal ATPase AAA_3 PF07726.6 CCU97863.1 - 0.00023 20.8 0.0 0.69 9.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CCU97863.1 - 0.00033 19.7 0.8 0.31 9.9 0.0 3.0 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.13 CCU97863.1 - 0.00037 20.1 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_30 PF13604.1 CCU97863.1 - 0.00067 19.2 0.0 0.96 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 CCU97863.1 - 0.0036 17.0 0.3 1.8 8.2 0.0 3.4 3 0 0 3 3 3 1 NTPase NB-ARC PF00931.17 CCU97863.1 - 0.0049 15.7 0.1 0.48 9.2 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.13 CCU97863.1 - 0.0059 16.1 0.0 0.41 10.1 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 CCU97863.1 - 0.011 14.6 0.0 0.32 9.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 CCU97863.1 - 0.022 14.2 1.6 6.5 6.1 0.0 3.9 3 1 0 4 4 4 0 AAA-like domain IPT PF01745.11 CCU97863.1 - 0.03 13.4 0.0 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 CCU97863.1 - 0.037 13.6 0.1 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 CCU97863.1 - 0.052 12.5 0.0 0.87 8.5 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain KTI12 PF08433.5 CCU97863.1 - 0.059 12.5 0.1 7.9 5.5 0.0 2.5 2 1 0 2 2 2 0 Chromatin associated protein KTI12 DEAD PF00270.24 CCU97863.1 - 0.11 12.0 0.5 59 3.0 0.0 3.4 3 1 1 4 4 3 0 DEAD/DEAH box helicase Zot PF05707.7 CCU97863.1 - 0.12 11.8 0.3 18 4.7 0.1 3.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) HSP70 PF00012.15 CCU97864.1 - 3.6e-153 510.6 0.0 1.1e-152 509.1 0.0 1.6 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CCU97864.1 - 1.7e-06 26.8 0.0 3.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Ribosomal_L30_N PF08079.7 CCU97865.1 - 1.1e-24 86.2 14.1 1.9e-24 85.4 9.8 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 CCU97865.1 - 8e-19 66.9 3.4 4e-18 64.7 0.3 2.6 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e ERCC4 PF02732.10 CCU97865.1 - 0.074 12.8 0.2 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 ERCC4 domain PGC7_Stella PF15549.1 CCU97865.1 - 0.3 11.0 5.2 0.49 10.3 3.6 1.2 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain COX16 PF14138.1 CCU97865.1 - 2.7 8.2 6.9 4.6 7.4 4.8 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 PX PF00787.19 CCU97866.1 - 1.4e-25 89.2 0.1 2e-25 88.7 0.1 1.2 1 0 0 1 1 1 1 PX domain SIR2 PF02146.12 CCU97868.1 - 2e-06 27.6 0.0 3.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Sir2 family V-SNARE_C PF12352.3 CCU97869.1 - 1.1e-13 50.9 0.8 2.6e-13 49.8 0.6 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Syntaxin-18_N PF10496.4 CCU97869.1 - 0.054 13.3 0.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Methyltransf_31 PF13847.1 CCU97870.1 - 3.1e-11 43.0 0.1 4.7e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCU97870.1 - 3.3e-10 40.5 0.0 6.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCU97870.1 - 5.7e-10 38.8 0.1 7.3e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 CCU97870.1 - 7.8e-09 35.9 0.0 1.7e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCU97870.1 - 2.4e-08 33.8 0.0 4.9e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 CCU97870.1 - 2.6e-07 29.9 0.0 4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 CCU97870.1 - 2.6e-06 27.4 0.0 5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCU97870.1 - 6.3e-06 26.5 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CCU97870.1 - 2e-05 23.4 0.1 3.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 CCU97870.1 - 2.9e-05 23.5 0.1 5e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 CCU97870.1 - 0.00011 21.3 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CCU97870.1 - 0.00016 22.0 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CCU97870.1 - 0.00067 19.6 0.2 0.001 19.0 0.1 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 CCU97870.1 - 0.0064 16.0 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 CCU97870.1 - 0.011 15.1 0.1 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 CCU97870.1 - 0.022 13.8 0.1 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 CCU97870.1 - 0.079 13.8 0.0 0.17 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 CCU97870.1 - 0.13 11.7 0.3 0.23 11.0 0.1 1.4 2 0 0 2 2 2 0 Met-10+ like-protein CTP_transf_1 PF01148.15 CCU97871.1 - 1.7e-70 237.6 29.5 6.2e-70 235.8 20.5 1.9 1 1 0 1 1 1 1 Cytidylyltransferase family DUF2953 PF11167.3 CCU97871.1 - 0.0045 16.8 1.6 0.0085 15.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2953) MFS_1 PF07690.11 CCU97874.1 - 2.5e-40 138.3 48.9 9.5e-40 136.3 33.4 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCU97874.1 - 6.4e-12 44.7 15.3 6.4e-12 44.7 10.6 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 CCU97874.1 - 1.1e-08 33.7 15.0 1.9e-08 33.0 10.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CIAPIN1 PF05093.8 CCU97875.1 - 6.9e-31 106.2 2.7 1.3e-30 105.4 1.8 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis SICA_beta PF12878.2 CCU97875.1 - 0.071 12.9 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 SICA extracellular beta domain PRCC PF10253.4 CCU97876.1 - 5e-13 50.1 12.3 5e-13 50.1 8.5 2.2 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Lsm_interact PF05391.6 CCU97876.1 - 0.02 14.2 0.0 0.15 11.5 0.0 2.6 1 0 0 1 1 1 0 Lsm interaction motif CAML PF14963.1 CCU97876.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand EMP24_GP25L PF01105.19 CCU97877.1 - 1.1e-26 93.6 0.0 1.4e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ran_BP1 PF00638.13 CCU97878.1 - 1.4e-13 50.9 0.0 2.3e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Tau95 PF09734.4 CCU97879.1 - 4.1e-35 121.5 0.0 2.1e-34 119.2 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DNA_pol_E_B PF04042.11 CCU97880.1 - 1.5e-15 57.0 1.1 6.7e-15 54.8 0.8 1.9 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 CCU97880.1 - 2.2e-15 56.8 0.0 4.8e-15 55.7 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal Tuberculin PF12198.3 CCU97880.1 - 0.019 14.8 0.1 0.46 10.3 0.0 2.4 2 0 0 2 2 2 0 Theoretical tuberculin protein Nop PF01798.13 CCU97881.1 - 1.2e-57 193.4 0.4 2.2e-57 192.5 0.3 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CCU97881.1 - 6.6e-27 93.0 0.1 1.1e-26 92.3 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CCU97881.1 - 2e-15 56.7 0.2 2e-15 56.7 0.1 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF4604 PF15377.1 CCU97881.1 - 0.018 15.2 26.4 0.027 14.6 18.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RNA_polI_A34 PF08208.6 CCU97881.1 - 0.12 11.9 36.7 0.24 11.0 25.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 CCU97881.1 - 0.45 10.4 13.1 0.64 9.9 9.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family CT47 PF15623.1 CCU97881.1 - 1.2 8.7 21.6 8 6.1 16.0 1.6 2 0 0 2 2 2 0 Cancer/testis gene family 47 CDC45 PF02724.9 CCU97881.1 - 3.1 5.6 23.6 11 3.9 0.0 2.1 2 0 0 2 2 2 0 CDC45-like protein Herpes_DNAp_acc PF04929.7 CCU97881.1 - 5 5.9 14.7 7.9 5.3 10.2 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DDHD PF02862.12 CCU97881.1 - 7.3 6.3 10.9 14 5.4 7.5 1.5 1 0 0 1 1 1 0 DDHD domain Rhodanese PF00581.15 CCU97882.1 - 8.7e-14 51.8 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain YqjK PF13997.1 CCU97882.1 - 0.0088 16.1 0.1 0.022 14.8 0.0 1.7 2 0 0 2 2 2 1 YqjK-like protein PT PF04886.7 CCU97883.1 - 0.00019 20.6 27.2 0.00019 20.6 18.9 3.4 2 1 1 3 3 3 1 PT repeat TP2 PF01254.13 CCU97883.1 - 3.6 7.9 12.1 0.12 12.6 3.7 2.1 2 0 0 2 2 2 0 Nuclear transition protein 2 PS_Dcarbxylase PF02666.10 CCU97884.1 - 1.5e-71 239.9 0.0 1.1e-55 188.0 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase NADH_oxidored PF08040.6 CCU97884.1 - 0.08 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 MNLL subunit Nup88 PF10168.4 CCU97885.1 - 3.6e-23 81.3 0.0 6.4e-14 50.7 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore component DUF2989 PF11207.3 CCU97885.1 - 0.08 12.3 0.7 0.17 11.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) DUF572 PF04502.8 CCU97885.1 - 8 5.5 8.7 12 4.9 6.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) FYVE PF01363.16 CCU97886.1 - 9.2e-20 70.3 7.8 9.2e-20 70.3 5.4 3.1 2 1 0 3 3 3 1 FYVE zinc finger FYVE_2 PF02318.11 CCU97886.1 - 0.014 15.2 7.2 0.014 15.2 5.0 2.9 3 1 0 3 3 3 0 FYVE-type zinc finger zf-RING_2 PF13639.1 CCU97886.1 - 0.018 14.8 5.1 0.018 14.8 3.5 3.8 2 1 1 3 3 3 0 Ring finger domain zf-C2H2_4 PF13894.1 CCU97886.1 - 0.13 12.6 0.5 0.13 12.6 0.3 3.7 2 1 1 3 3 3 0 C2H2-type zinc finger Ribosomal_L29e PF01779.12 CCU97887.1 - 7.7e-13 48.0 2.7 2.6e-12 46.4 1.9 1.8 1 1 0 1 1 1 1 Ribosomal L29e protein family DUF2404 PF10296.4 CCU97888.1 - 0.0056 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) THDPS_M PF14789.1 CCU97888.1 - 0.03 14.2 1.4 23 5.0 0.0 3.6 3 0 0 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase middle SSF PF00474.12 CCU97890.1 - 2.7e-14 52.6 20.4 4.5e-14 51.9 14.1 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Peptidase_M50 PF02163.17 CCU97890.1 - 0.32 9.9 3.4 1.8 7.4 2.4 2.5 1 1 0 1 1 1 0 Peptidase family M50 DIOX_N PF14226.1 CCU97891.1 - 1.1e-11 45.3 0.0 2.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCU97891.1 - 1.3e-10 41.3 0.0 3.7e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FMO-like PF00743.14 CCU97892.1 - 4.9e-31 107.5 0.0 1.3e-12 46.7 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCU97892.1 - 2.2e-20 73.5 0.0 6e-14 52.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCU97892.1 - 1.1e-07 31.7 0.1 9.6e-05 22.2 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 CCU97892.1 - 2.4e-07 29.9 0.2 0.0088 15.0 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CCU97892.1 - 1.8e-05 24.6 0.1 0.00047 20.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCU97892.1 - 4.4e-05 23.4 0.0 0.0051 16.7 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCU97892.1 - 0.031 14.6 0.2 9 6.7 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCU97892.1 - 0.061 12.2 0.0 2.4 6.9 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.12 CCU97892.1 - 0.072 12.1 0.1 3.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 CCU97892.1 - 0.15 10.4 0.2 0.27 9.6 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein OCD_Mu_crystall PF02423.10 CCU97892.1 - 0.2 10.4 0.1 0.31 9.7 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family TauD PF02668.11 CCU97893.1 - 1.1e-37 130.0 0.0 1.5e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family B3_4 PF03483.12 CCU97894.1 - 5e-26 91.2 0.0 1e-25 90.1 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CCU97894.1 - 1.8e-16 59.6 0.0 1.4e-14 53.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain ETF_QO PF05187.8 CCU97895.1 - 1.3e-41 141.0 0.0 2.4e-41 140.1 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase FAD_binding_2 PF00890.19 CCU97895.1 - 4.7e-07 29.0 1.8 0.00014 20.8 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 CCU97895.1 - 1.1e-06 27.8 4.8 0.00031 19.7 1.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCU97895.1 - 2.5e-06 27.4 0.1 7.8e-06 25.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CCU97895.1 - 3.7e-05 23.0 0.1 6.2e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCU97895.1 - 4e-05 23.5 0.1 0.0001 22.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCU97895.1 - 6.1e-05 21.6 1.2 9.5e-05 21.0 0.9 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 CCU97895.1 - 8.7e-05 21.7 0.1 0.0002 20.5 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 CCU97895.1 - 0.00071 18.6 0.3 0.0012 17.8 0.1 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 CCU97895.1 - 0.0015 17.6 0.2 0.0028 16.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.2 CCU97895.1 - 0.0033 17.7 1.1 0.0073 16.6 0.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.1 CCU97895.1 - 0.0041 17.1 0.1 0.0079 16.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCU97895.1 - 0.0079 15.9 0.2 0.015 15.1 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_10 PF13237.1 CCU97895.1 - 0.019 14.7 0.7 0.033 13.9 0.5 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.1 CCU97895.1 - 0.021 14.6 0.6 0.043 13.6 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 CCU97895.1 - 0.073 13.0 0.8 0.19 11.7 0.5 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain DUF4147 PF13660.1 CCU97895.1 - 0.075 12.1 0.2 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Trp_halogenase PF04820.9 CCU97895.1 - 0.098 11.2 0.4 0.19 10.3 0.3 1.5 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 CCU97895.1 - 0.11 11.3 0.9 0.17 10.6 0.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_6 PF12837.2 CCU97895.1 - 3.4 7.6 5.0 0.99 9.3 0.6 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain DPBB_1 PF03330.13 CCU97896.1 - 7.4e-06 25.8 0.1 6.4e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CCU97896.1 - 1.3e-05 24.8 0.5 1.8e-05 24.3 0.3 1.3 1 1 0 1 1 1 1 Barwin family FYVE PF01363.16 CCU97897.1 - 6.6e-17 61.1 5.2 1.5e-16 60.0 3.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.3 CCU97897.1 - 0.011 15.2 3.1 0.033 13.7 2.2 1.9 1 0 0 1 1 1 0 Rabenosyn Rab binding domain DUF4349 PF14257.1 CCU97897.1 - 0.052 12.7 6.6 0.031 13.5 3.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) C1_1 PF00130.17 CCU97897.1 - 0.21 11.3 7.3 13 5.5 2.0 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.14 CCU97897.1 - 0.24 11.1 1.8 1.5 8.5 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Meth_synt_2 PF01717.13 CCU97899.1 - 4.3e-144 479.4 0.0 9.5e-139 461.8 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CCU97899.1 - 5.5e-123 410.1 0.0 2.1e-109 365.5 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.4 CCU97899.1 - 0.00041 19.7 1.7 0.00041 19.7 1.2 2.0 2 0 0 2 2 2 1 Short C-terminal domain HMGL-like PF00682.14 CCU97899.1 - 0.097 12.3 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 HMGL-like Y_phosphatase PF00102.22 CCU97902.1 - 4.9e-26 91.5 0.0 1.9e-24 86.3 0.0 2.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CCU97902.1 - 8e-09 35.1 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain SLT_L PF14718.1 CCU97903.1 - 0.077 12.8 2.1 0.16 11.7 1.5 1.5 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain Syntaxin PF00804.20 CCU97903.1 - 0.5 10.5 2.7 2.2 8.5 0.0 2.8 3 1 0 3 3 3 0 Syntaxin IF4E PF01652.13 CCU97904.1 - 4.2e-48 162.9 0.1 5.5e-48 162.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.20 CCU97905.1 - 9.1e-64 215.0 0.1 1.3e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97905.1 - 4.1e-28 98.1 0.0 5.8e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU97905.1 - 2.4e-06 26.7 0.0 4.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCU97905.1 - 0.0047 16.6 0.0 0.76 9.4 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCU97905.1 - 0.039 13.0 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pex16 PF08610.5 CCU97905.1 - 0.21 10.5 0.6 0.35 9.8 0.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Macoilin PF09726.4 CCU97905.1 - 1.4 7.1 10.6 1.9 6.6 7.4 1.1 1 0 0 1 1 1 0 Transmembrane protein ALAD PF00490.16 CCU97906.1 - 6.6e-110 367.0 0.0 7.4e-110 366.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase ATP_bind_1 PF03029.12 CCU97907.1 - 2.9e-17 62.9 0.3 3.4e-17 62.7 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Cwf_Cwc_15 PF04889.7 CCU97908.1 - 3.8e-47 161.0 15.6 5.1e-47 160.6 10.8 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein PRP1_N PF06424.7 CCU97908.1 - 0.084 13.2 8.7 0.13 12.5 6.0 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal SAPS PF04499.10 CCU97908.1 - 3.1 6.3 7.3 3.9 5.9 5.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein tRNA_m1G_MT PF01746.16 CCU97909.1 - 1.5e-25 89.9 0.0 5e-22 78.4 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Pkinase PF00069.20 CCU97910.1 - 5.6e-60 202.6 0.2 6.8e-40 136.8 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97910.1 - 2.8e-25 88.8 0.1 5e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCU97910.1 - 3.7e-05 22.8 1.8 0.00026 20.0 0.0 2.5 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 CCU97910.1 - 0.00042 20.1 0.1 0.021 14.5 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCU97910.1 - 0.0078 15.3 0.0 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CCU97910.1 - 0.024 13.4 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_C PF00433.19 CCU97910.1 - 0.027 14.9 0.1 0.056 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 CCU97910.1 - 0.032 13.0 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 GDC-P PF02347.11 CCU97911.1 - 4.8e-182 605.4 0.1 1.2e-171 571.1 0.0 2.7 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 CCU97911.1 - 7.7e-06 24.8 0.8 0.05 12.3 0.3 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCU97911.1 - 2.3e-05 23.6 0.1 4.5e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Hexokinase_2 PF03727.11 CCU97912.1 - 5e-75 251.8 0.0 1.6e-74 250.1 0.0 1.7 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.16 CCU97912.1 - 2.1e-66 223.1 0.0 3.1e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase ROK PF00480.15 CCU97912.1 - 0.033 14.0 0.0 0.15 11.8 0.0 2.0 1 1 0 1 1 1 0 ROK family DUF1731 PF08338.6 CCU97912.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Amino_oxidase PF01593.19 CCU97913.1 - 0.00027 20.1 0.0 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribosomal_L44 PF00935.14 CCU97914.1 - 4.6e-35 119.4 12.6 7e-35 118.8 8.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Pkinase PF00069.20 CCU97915.1 - 1.4e-69 234.1 0.0 1.7e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97915.1 - 6.5e-29 100.7 0.0 9e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCU97915.1 - 0.16 11.0 0.4 0.35 9.9 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Slu7 PF11708.3 CCU97916.1 - 3.5e-71 239.7 22.8 5.7e-71 239.0 15.8 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor RRF PF01765.14 CCU97917.1 - 7.5e-27 93.8 3.4 3.5e-26 91.6 2.4 1.8 1 1 0 1 1 1 1 Ribosome recycling factor TFIID-31kDa PF02291.10 CCU97918.1 - 2.7e-43 146.8 0.0 3.7e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 CCU97918.1 - 4.7e-05 23.0 0.0 8.8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 CCU97918.1 - 0.043 13.9 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Adap_comp_sub PF00928.16 CCU97919.1 - 3.2e-22 78.9 0.0 4.7e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CCU97919.1 - 8e-05 22.3 0.5 0.00013 21.7 0.3 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 CCU97919.1 - 0.0071 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Plasmodium_HRP PF05403.6 CCU97919.1 - 0.1 12.1 13.1 0.18 11.3 9.1 1.2 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) Mis12 PF05859.7 CCU97921.1 - 1.3e-17 63.9 0.0 2e-17 63.3 0.0 1.4 1 1 0 1 1 1 1 Mis12 protein HCaRG PF07258.9 CCU97921.1 - 0.081 12.4 0.4 3.2 7.2 0.0 2.1 2 0 0 2 2 2 0 HCaRG protein zf-CCHC PF00098.18 CCU97922.1 - 1.9e-11 43.2 12.5 1.3e-06 28.0 1.0 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CCU97922.1 - 4.8e-05 22.9 12.4 0.00065 19.3 2.6 2.4 1 1 1 2 2 2 2 Zinc knuckle DUF1897 PF09005.5 CCU97922.1 - 0.0016 17.8 30.7 0.11 11.9 9.8 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF1897) zf-CCHC_5 PF14787.1 CCU97922.1 - 0.0051 16.2 2.7 0.0051 16.2 1.9 2.9 3 0 0 3 3 3 1 GAG-polyprotein viral zinc-finger Ribosomal_L37e PF01907.14 CCU97922.1 - 0.46 10.3 7.2 0.14 11.9 0.9 2.5 2 0 0 2 2 2 0 Ribosomal protein L37e DZR PF12773.2 CCU97922.1 - 0.49 10.2 5.5 1.4 8.7 3.8 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-CCHC_2 PF13696.1 CCU97922.1 - 0.74 9.3 7.3 0.59 9.6 1.0 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CCU97922.1 - 1.7 8.4 11.9 3 7.5 0.9 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-RING_5 PF14634.1 CCU97922.1 - 3.1 7.5 9.5 6.5 6.5 0.5 2.5 2 0 0 2 2 2 0 zinc-RING finger domain CTP_transf_1 PF01148.15 CCU97923.1 - 2.7e-15 56.7 6.6 4.3e-14 52.7 4.5 2.4 1 1 0 1 1 1 1 Cytidylyltransferase family HAT PF02184.11 CCU97924.1 - 1.1e-09 37.8 27.8 0.01 15.5 0.0 8.9 9 1 0 9 9 9 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 CCU97924.1 - 5.6e-08 32.7 9.6 0.1 13.2 0.0 6.9 5 2 2 7 7 6 2 Tetratricopeptide repeat Suf PF05843.9 CCU97924.1 - 3.4e-07 30.2 3.7 0.15 11.7 0.1 4.9 3 1 1 4 4 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 CCU97924.1 - 1.7e-05 25.0 2.7 0.062 13.6 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCU97924.1 - 5.1e-05 23.8 3.5 0.14 12.8 0.0 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.5 CCU97924.1 - 0.0093 14.8 6.5 0.31 9.8 0.0 3.9 1 1 3 4 4 4 1 NRDE-2, necessary for RNA interference TPR_2 PF07719.12 CCU97924.1 - 0.02 14.7 1.7 16 5.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCU97924.1 - 0.021 14.9 0.7 0.37 11.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCU97924.1 - 0.031 14.2 10.6 5.5 7.0 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CCU97924.1 - 0.12 12.1 7.9 0.093 12.5 0.3 3.6 4 1 0 4 4 4 0 Mad3/BUB1 homology region 1 TPR_7 PF13176.1 CCU97924.1 - 0.29 11.0 9.2 15 5.6 0.1 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat MRP-L20 PF12824.2 CCU97925.1 - 5.6e-29 101.2 2.4 1.2e-28 100.1 1.6 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Pyr_redox_2 PF07992.9 CCU97925.1 - 5.6e-08 32.9 0.0 1.3e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCU97925.1 - 1.2e-05 25.1 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 CCU97925.1 - 0.00019 20.4 0.1 0.0067 15.3 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 CCU97925.1 - 0.0013 17.6 0.4 1.3 7.8 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CCU97925.1 - 0.0062 16.6 0.0 0.069 13.2 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCU97925.1 - 0.038 12.8 0.1 0.22 10.3 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 CCU97925.1 - 0.065 12.2 0.0 1.1 8.2 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain Apo-VLDL-II PF05418.6 CCU97925.1 - 0.081 13.1 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Apovitellenin I (Apo-VLDL-II) DEAD PF00270.24 CCU97926.1 - 3.2e-22 78.8 0.0 5e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU97926.1 - 4.8e-20 71.2 0.0 1.4e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AA_permease_2 PF13520.1 CCU97927.1 - 2.2e-55 187.9 47.9 2.7e-55 187.6 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCU97927.1 - 2.1e-07 29.6 39.3 3.3e-07 29.0 27.2 1.2 1 0 0 1 1 1 1 Amino acid permease PH_4 PF15404.1 CCU97929.1 - 2.9e-21 75.8 1.2 8.6e-19 67.7 0.2 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 CCU97929.1 - 2.3e-05 24.5 0.0 0.0043 17.2 0.0 3.0 3 0 0 3 3 3 1 PH domain VGCC_beta4Aa_N PF12052.3 CCU97929.1 - 0.33 10.8 4.4 0.17 11.7 0.6 2.4 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Ribosom_S12_S23 PF00164.20 CCU97930.1 - 6e-46 154.8 0.1 8.2e-46 154.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 EF1_GNE PF00736.14 CCU97931.1 - 5.2e-32 109.3 3.9 1e-31 108.4 2.7 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CCU97931.1 - 4.9e-13 48.9 8.1 4.9e-13 48.9 5.6 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 CCU97931.1 - 0.00068 20.0 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCU97931.1 - 0.037 13.8 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GRA6 PF05084.8 CCU97931.1 - 0.046 13.2 1.3 4.9 6.6 0.5 2.2 2 0 0 2 2 2 0 Granule antigen protein (GRA6) DNA_pol3_a_NII PF11490.3 CCU97931.1 - 0.39 10.3 5.0 0.63 9.6 0.1 2.5 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus II PHD PF00628.24 CCU97932.1 - 5.1e-09 35.6 7.1 7.9e-09 35.0 4.9 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 CCU97932.1 - 8.8e-05 22.7 0.0 0.00018 21.7 0.0 1.6 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 CCU97932.1 - 0.048 13.7 0.2 0.092 12.9 0.2 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 CCU97932.1 - 0.25 10.6 2.9 0.43 9.9 2.0 1.3 1 0 0 1 1 1 0 PHD-finger FKBP_C PF00254.23 CCU97933.1 - 1.8e-32 111.2 0.0 2.1e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NTF2 PF02136.15 CCU97934.1 - 8.8e-34 116.4 0.3 9.9e-34 116.2 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 CCU97934.1 - 0.13 12.5 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Asp PF00026.18 CCU97935.1 - 1.1e-64 218.7 8.9 1.6e-64 218.2 6.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCU97935.1 - 2.1e-09 37.5 0.8 4.2e-09 36.5 0.2 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCU97935.1 - 2.5e-06 27.8 2.8 0.01 16.3 0.3 3.2 2 2 0 2 2 2 2 Aspartyl protease RVP PF00077.15 CCU97935.1 - 0.00017 21.4 0.1 0.0029 17.4 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Bromodomain PF00439.20 CCU97937.1 - 6.6e-58 192.6 0.2 7.1e-21 73.9 0.1 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 CCU97937.1 - 1.1e-09 37.9 0.0 2.6e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M1 Med7 PF05983.6 CCU97938.1 - 1.9e-30 105.8 0.0 6.6e-30 104.0 0.0 1.7 1 1 0 1 1 1 1 MED7 protein DUF1470 PF07336.6 CCU97938.1 - 0.0034 17.7 5.1 0.85 9.9 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1470) AAA_12 PF13087.1 CCU97939.1 - 4.7e-45 153.4 0.0 6.7e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCU97939.1 - 3e-37 128.4 1.7 1.7e-19 70.3 0.2 2.4 1 1 1 2 2 2 2 AAA domain Dna2 PF08696.6 CCU97939.1 - 5e-33 114.1 0.0 1.4e-31 109.4 0.0 2.2 1 1 0 1 1 1 1 DNA replication factor Dna2 AAA_30 PF13604.1 CCU97939.1 - 1.2e-13 51.0 0.3 6.7e-12 45.3 0.0 3.1 3 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 CCU97939.1 - 2e-07 30.7 0.9 0.058 12.9 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CCU97939.1 - 2.1e-07 30.5 0.7 2.1e-07 30.5 0.5 3.0 3 0 0 3 3 3 1 Part of AAA domain Helicase_RecD PF05127.9 CCU97939.1 - 3.1e-05 23.6 0.1 9.8e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Helicase MobB PF03205.9 CCU97939.1 - 0.0019 17.8 0.1 0.004 16.8 0.1 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Cas_Cas4 PF01930.12 CCU97939.1 - 0.0031 17.4 0.1 0.061 13.2 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function DUF83 AAA_16 PF13191.1 CCU97939.1 - 0.011 15.7 1.8 0.039 13.9 0.9 2.4 1 1 1 2 2 2 0 AAA ATPase domain UvrD_C_2 PF13538.1 CCU97939.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF87 PF01935.12 CCU97939.1 - 0.012 15.4 0.1 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 SRP54 PF00448.17 CCU97939.1 - 0.025 14.0 0.1 0.045 13.1 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 CCU97939.1 - 0.041 14.0 0.0 0.41 10.8 0.0 2.7 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CCU97939.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain CbiA PF01656.18 CCU97939.1 - 0.23 10.8 0.1 0.51 9.7 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HSDR_N_2 PF13588.1 CCU97939.1 - 0.29 10.9 0.0 0.6 9.9 0.0 1.4 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF2075 PF09848.4 CCU97939.1 - 0.43 9.4 0.0 1.1 8.2 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AA_permease PF00324.16 CCU97940.1 - 0 1281.4 122.0 1.8e-134 448.6 25.3 3.0 3 0 0 3 3 3 3 Amino acid permease AA_permease_2 PF13520.1 CCU97940.1 - 3.1e-125 418.0 131.1 2.1e-45 155.0 28.6 3.1 3 0 0 3 3 3 3 Amino acid permease DUF2665 PF11654.3 CCU97940.1 - 0.00058 19.3 1.9 7.1 6.2 0.1 4.8 4 0 0 4 4 4 2 Protein of unknown function (DUF2665) CCAP PF11105.3 CCU97940.1 - 0.17 11.6 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a AA_permease PF00324.16 CCU97941.1 - 3.5e-74 249.8 14.4 3.5e-74 249.8 10.0 1.6 1 1 1 2 2 2 1 Amino acid permease AA_permease_2 PF13520.1 CCU97941.1 - 3.3e-22 78.6 12.3 4.2e-22 78.2 8.5 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 CCU97941.1 - 0.0078 15.9 3.7 0.49 10.1 0.5 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) DUF2207 PF09972.4 CCU97941.1 - 3.4 6.1 6.7 0.16 10.5 0.6 1.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) SKIP_SNW PF02731.10 CCU97942.1 - 2.1e-59 199.5 3.9 2.1e-59 199.5 2.7 2.6 3 0 0 3 3 3 1 SKIP/SNW domain Coprogen_oxidas PF01218.13 CCU97943.1 - 3e-103 344.4 0.0 4e-67 225.8 0.0 2.4 1 1 0 2 2 2 2 Coproporphyrinogen III oxidase DUF4112 PF13430.1 CCU97944.1 - 2.2e-26 91.8 0.1 3.3e-26 91.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Pkinase PF00069.20 CCU97945.1 - 2.9e-57 193.7 0.0 5.4e-56 189.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU97945.1 - 4.2e-25 88.3 0.0 1.4e-24 86.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU97945.1 - 2e-07 30.2 0.0 3.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_3 PF14593.1 CCU97945.1 - 3.8e-07 29.9 0.0 0.0045 16.8 0.0 2.4 2 0 0 2 2 2 2 PH domain APH PF01636.18 CCU97945.1 - 0.0027 17.4 0.0 0.008 15.9 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCU97945.1 - 0.0088 15.1 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HC2 PF07382.6 CCU97946.1 - 7.3 6.4 16.4 0.4 10.5 1.1 2.9 1 1 1 3 3 3 0 Histone H1-like nucleoprotein HC2 RRM_1 PF00076.17 CCU97947.1 - 6.6e-12 44.8 0.0 7.7e-06 25.4 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU97947.1 - 7.8e-10 38.5 0.0 1.9e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU97947.1 - 1.5e-06 27.9 0.0 0.0006 19.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCU97947.1 - 0.37 10.5 2.6 0.94 9.2 0.1 2.5 3 0 0 3 3 3 0 Limkain b1 polyprenyl_synt PF00348.12 CCU97948.1 - 7e-42 143.0 0.0 1.3e-36 125.7 0.0 3.6 2 1 0 2 2 2 2 Polyprenyl synthetase Pept_tRNA_hydro PF01195.14 CCU97949.1 - 4.6e-26 91.4 0.0 9.8e-22 77.3 0.0 2.1 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase F-box-like PF12937.2 CCU97951.1 - 0.0064 16.1 0.4 0.037 13.7 0.3 2.5 1 0 0 1 1 1 1 F-box-like DUF572 PF04502.8 CCU97952.1 - 1.2e-79 267.9 3.5 1.3e-79 267.7 2.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.9 CCU97952.1 - 0.0029 17.2 0.8 0.81 9.3 0.1 2.5 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif DUF866 PF05907.8 CCU97952.1 - 0.041 13.3 0.1 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Benyvirus_14KDa PF07255.6 CCU97952.1 - 0.072 12.9 0.2 0.24 11.2 0.0 1.7 1 1 1 2 2 2 0 Benyvirus 14KDa protein C1_3 PF07649.7 CCU97952.1 - 0.083 12.9 2.5 1.5 8.9 0.1 2.2 2 0 0 2 2 2 0 C1-like domain Lar_restr_allev PF14354.1 CCU97952.1 - 0.14 12.4 0.7 3.7 7.9 0.8 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar GCIP PF13324.1 CCU97953.1 - 5e-05 22.6 0.5 0.00013 21.3 0.0 2.0 3 0 0 3 3 3 1 Grap2 and cyclin-D-interacting DUF2077 PF09850.4 CCU97953.1 - 0.15 11.4 1.9 9.9 5.5 0.1 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) Tyr_Deacylase PF02580.11 CCU97954.1 - 3e-34 118.0 0.0 5.2e-34 117.3 0.0 1.4 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Inositol_P PF00459.20 CCU97956.1 - 1.3e-65 221.3 0.0 1.5e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family adh_short PF00106.20 CCU97959.1 - 8.8e-20 71.2 0.0 1.5e-19 70.5 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCU97959.1 - 9.2e-09 35.2 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCU97959.1 - 1.4e-07 31.5 0.0 1.9e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SMC_hinge PF06470.8 CCU97959.1 - 0.0016 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain NAD_binding_10 PF13460.1 CCU97959.1 - 0.004 17.1 0.0 0.0055 16.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCU97959.1 - 0.0093 15.4 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 CCU97959.1 - 0.071 13.2 0.0 0.094 12.8 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-C2H2_2 PF12756.2 CCU97960.1 - 0.0093 16.0 0.1 0.02 14.9 0.1 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Asp-B-Hydro_N PF05279.6 CCU97960.1 - 0.19 11.5 22.1 0.27 11.0 15.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GCD14 PF08704.5 CCU97963.1 - 1.2e-78 264.0 4.0 2.5e-47 161.4 1.6 3.1 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 CCU97963.1 - 1.9e-06 27.8 0.1 3.4e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCU97963.1 - 0.00039 20.9 0.8 1.6 9.3 0.0 3.1 2 1 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 CCU97963.1 - 0.004 16.7 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain PCMT PF01135.14 CCU97963.1 - 0.015 14.8 0.0 0.061 12.8 0.0 1.9 3 0 0 3 3 3 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 CCU97963.1 - 0.025 15.4 0.1 0.12 13.2 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 CCU97963.1 - 0.042 12.8 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CBF PF03914.12 CCU97964.1 - 9e-40 135.8 0.1 5.2e-39 133.3 0.0 2.4 3 0 0 3 3 3 1 CBF/Mak21 family Adaptin_N PF01602.15 CCU97964.1 - 0.00091 17.6 0.0 0.39 8.9 0.0 2.2 2 0 0 2 2 2 2 Adaptin N terminal region TFIIS_M PF07500.9 CCU97965.1 - 1.2e-29 102.7 4.3 2.2e-29 101.8 0.7 2.5 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CCU97965.1 - 5.6e-19 67.4 7.1 1.1e-18 66.5 4.9 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CCU97965.1 - 4.1e-09 35.8 0.6 1.3e-08 34.1 0.4 2.0 1 1 0 1 1 1 1 TFIIS helical bundle-like domain 2-Hacid_dh PF00389.25 CCU97965.1 - 0.017 14.5 0.1 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Baculo_LEF5_C PF11792.3 CCU97965.1 - 0.15 11.4 0.5 0.37 10.2 0.2 1.8 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Borrelia_REV PF03978.8 CCU97965.1 - 0.19 11.4 5.3 0.38 10.4 0.4 2.7 2 1 0 2 2 2 0 Borrelia burgdorferi REV protein DnaJ PF00226.26 CCU97966.1 - 4.3e-25 87.2 0.7 6.3e-25 86.7 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain IBR PF01485.16 CCU97966.1 - 0.024 14.5 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 IBR domain Rad50_zn_hook PF04423.9 CCU97966.1 - 0.025 14.0 0.0 0.068 12.6 0.0 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif DnaJ-X PF14308.1 CCU97967.1 - 3.7e-40 137.3 2.8 3.7e-40 137.3 1.9 2.0 2 1 0 2 2 2 1 X-domain of DnaJ-containing TMEM187 PF15100.1 CCU97967.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 TMEM187 protein family UDPGT PF00201.13 CCU97967.1 - 0.05 12.1 0.0 0.074 11.5 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase PEX11 PF05648.9 CCU97967.1 - 0.15 11.3 1.1 0.45 9.7 0.0 2.0 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) OmpH PF03938.9 CCU97967.1 - 3.2 7.6 20.4 17 5.2 11.7 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) ThiF PF00899.16 CCU97968.1 - 2.1e-10 40.5 0.0 4.9e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 ThiF family DUF982 PF06169.7 CCU97968.1 - 0.72 9.6 7.8 0.2 11.4 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF982) PSK_trans_fac PF07704.6 CCU97969.1 - 0.022 15.4 0.1 0.075 13.7 0.1 1.9 1 0 0 1 1 1 0 Rv0623-like transcription factor UCH PF00443.24 CCU97970.1 - 4.5e-38 130.8 0.0 5.6e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCU97970.1 - 7.2e-15 55.1 0.0 8.5e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-H2C2_5 PF13909.1 CCU97970.1 - 0.13 12.5 0.4 0.13 12.5 0.2 1.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Abhydrolase_3 PF07859.8 CCU97971.1 - 2e-22 79.8 0.0 5.2e-22 78.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CCU97971.1 - 3.6e-17 62.0 0.0 1.1e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Thioesterase PF00975.15 CCU97971.1 - 0.031 14.4 0.0 0.054 13.7 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain zf-C2H2 PF00096.21 CCU97972.1 - 0.2 12.0 17.8 0.22 11.9 0.4 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCU97972.1 - 0.42 11.0 17.6 0.24 11.8 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Glyoxalase PF00903.20 CCU97973.1 - 1.3e-18 67.1 0.1 1.7e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CCU97973.1 - 4.6e-13 49.7 0.0 6.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CCU97973.1 - 4.8e-07 29.7 0.0 7.9e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 CCU97973.1 - 0.0014 18.5 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain tRNA-synt_1b PF00579.20 CCU97974.1 - 5.9e-63 212.7 0.0 1.8e-62 211.0 0.0 1.8 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) EMP24_GP25L PF01105.19 CCU97975.1 - 6.4e-28 97.7 0.1 7.8e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Herpes_UL45 PF05473.7 CCU97976.1 - 0.095 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 UL45 protein WD40 PF00400.27 CCU97978.1 - 4.2e-42 140.5 20.4 1.5e-09 37.3 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 CCU97978.1 - 0.0012 18.6 6.5 0.0067 16.1 0.1 3.6 3 2 2 5 5 5 1 Transcription factor IIIC subunit delta N-term HA2 PF04408.18 CCU97979.1 - 8.2e-30 102.8 0.0 1.5e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCU97979.1 - 1.3e-24 86.1 0.0 2.9e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCU97979.1 - 1.2e-11 44.2 0.0 4.1e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCU97979.1 - 2.2e-07 30.5 0.1 4.8e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCU97979.1 - 4e-05 23.7 0.0 9.9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCU97979.1 - 0.0082 15.0 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 CCU97979.1 - 0.0087 15.8 0.3 0.025 14.3 0.1 1.7 2 0 0 2 2 2 1 Flavivirus DEAD domain SRP54 PF00448.17 CCU97979.1 - 0.062 12.7 1.0 0.6 9.5 0.7 2.2 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 CCU97979.1 - 0.088 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Nucleopor_Nup85 PF07575.8 CCU97980.1 - 5.2e-71 239.5 0.1 8.6e-71 238.8 0.1 1.3 1 0 0 1 1 1 1 Nup85 Nucleoporin Arch_fla_DE PF04659.8 CCU97980.1 - 0.041 13.6 0.1 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Archaeal flagella protein Ribosomal_L14 PF00238.14 CCU97981.1 - 6.7e-34 116.2 0.0 7.5e-34 116.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e GTP_cyclohydroI PF01227.17 CCU97982.1 - 3.1e-73 244.8 0.1 3.8e-73 244.5 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CCU97982.1 - 0.0006 19.7 0.0 0.0015 18.4 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 CCU97982.1 - 0.016 14.9 0.1 0.05 13.3 0.1 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain KAR PF15222.1 CCU97982.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Kidney androgen-regulated Cyt-b5 PF00173.23 CCU97983.1 - 1.6e-24 85.5 0.2 1.7e-24 85.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.1 CCU97983.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Cpn60_TCP1 PF00118.19 CCU97984.1 - 6.4e-148 493.3 0.1 7.4e-148 493.1 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chitin_synth_1 PF01644.12 CCU97985.1 - 8.8e-77 256.4 0.1 1.3e-76 255.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CCU97985.1 - 2.3e-29 100.9 0.0 7.5e-29 99.2 0.0 2.0 1 0 0 1 1 1 1 Chitin synthase N-terminal EF-hand_4 PF12763.2 CCU97985.1 - 3.2e-16 58.9 0.0 7.9e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_9 PF14604.1 CCU97985.1 - 2.5e-10 39.7 0.1 2.7e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Chitin_synth_2 PF03142.10 CCU97985.1 - 3.3e-10 39.0 0.0 6.8e-10 37.9 0.0 1.4 1 1 0 1 1 1 1 Chitin synthase WH2 PF02205.15 CCU97985.1 - 5.4e-10 38.5 1.3 1.1e-09 37.5 0.9 1.5 1 0 0 1 1 1 1 WH2 motif SH3_1 PF00018.23 CCU97985.1 - 5.9e-10 38.3 0.0 2.9e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CCU97985.1 - 7.3e-05 22.1 0.0 0.00044 19.6 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain EF-hand_7 PF13499.1 CCU97985.1 - 0.0002 21.4 0.0 0.00054 20.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CCU97985.1 - 0.17 11.2 0.0 2 7.9 0.0 2.5 2 0 0 2 2 2 0 EF hand PTPlike_phytase PF14566.1 CCU97986.1 - 3.3e-120 397.1 1.9 1.3e-41 142.1 0.4 3.3 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase PF00102.22 CCU97986.1 - 2.4e-06 27.0 0.1 0.029 13.7 0.0 3.4 3 0 0 3 3 3 2 Protein-tyrosine phosphatase DSPc PF00782.15 CCU97986.1 - 5.2e-06 26.0 0.0 0.64 9.6 0.0 3.7 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCU97986.1 - 1.9e-05 25.0 0.9 0.58 10.3 0.0 3.9 4 0 0 4 4 4 2 Tyrosine phosphatase family TFIIE-A_C-term PF11521.3 CCU97986.1 - 0.0016 18.3 0.0 16 5.5 0.0 3.6 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha TcpQ PF10671.4 CCU97986.1 - 0.048 13.5 0.1 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q Ribosomal_L22 PF00237.14 CCU97987.1 - 1.7e-32 111.4 0.0 2.6e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Transket_pyr PF02779.19 CCU97988.1 - 7.9e-61 204.6 0.0 1.2e-60 204.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CCU97988.1 - 1.4e-60 204.5 0.0 2e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Rho_RNA_bind PF07497.7 CCU97988.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain ELFV_dehydrog PF00208.16 CCU97989.1 - 9.2e-13 48.3 0.0 7.5e-11 42.0 0.0 2.1 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RRM_1 PF00076.17 CCU97990.1 - 1.1e-60 201.1 0.0 8.8e-19 66.9 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU97990.1 - 1.4e-47 159.4 0.0 4.4e-13 49.0 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU97990.1 - 7.3e-19 67.3 0.0 0.00011 21.9 0.0 5.0 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOA36 PF06524.7 CCU97990.1 - 2.8 7.1 9.2 7.4 5.7 6.4 1.7 1 0 0 1 1 1 0 NOA36 protein DUF3357 PF11837.3 CCU97991.1 - 0.11 12.3 1.0 21 5.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) WD40 PF00400.27 CCU97992.1 - 1.5e-69 227.5 19.3 1.1e-14 53.5 0.9 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCU97992.1 - 2.1e-10 39.9 0.1 0.37 10.3 0.0 5.6 6 1 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 CCU97992.1 - 0.001 18.8 0.2 1.7 8.2 0.0 3.1 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 CCU97992.1 - 0.027 14.1 1.4 18 5.0 0.0 4.0 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Nucleoporin_N PF08801.6 CCU97992.1 - 0.029 13.1 0.0 6.6 5.3 0.0 2.5 2 1 0 2 2 2 0 Nup133 N terminal like Zn_clus PF00172.13 CCU97993.1 - 1.2e-05 25.1 10.0 2.1e-05 24.3 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Maf PF02545.9 CCU97995.1 - 3.8e-48 163.2 0.0 4.9e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein NOC3p PF07540.6 CCU97995.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Nucleolar complex-associated protein MRP-S25 PF13741.1 CCU97996.1 - 7.1e-17 61.6 0.0 9.1e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 2-Hacid_dh_C PF02826.14 CCU97997.1 - 1.7e-50 170.6 0.0 2.6e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCU97997.1 - 7.9e-34 115.9 0.0 1.1e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCU97997.1 - 0.0011 18.8 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 CCU97997.1 - 0.016 14.8 0.1 4 7.0 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M15_4 PF13539.1 CCU97997.1 - 0.061 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase AdoHcyase_NAD PF00670.16 CCU97997.1 - 0.095 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Septin PF00735.13 CCU97998.1 - 2.8e-89 298.8 2.6 1.3e-87 293.4 0.0 2.4 2 1 1 3 3 3 2 Septin Chs3p PF12271.3 CCU97999.1 - 4.9e-83 278.5 19.7 5.6e-83 278.3 13.6 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit COX7a PF02238.10 CCU98000.1 - 0.067 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa Oxidored_FMN PF00724.15 CCU98001.1 - 2.8e-57 194.2 0.0 3.7e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CDC73 PF05179.9 CCU98002.1 - 1.7e-28 99.7 0.0 2.5e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Chorismate_synt PF01264.16 CCU98003.1 - 7.5e-134 445.5 0.0 8.7e-134 445.3 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Phage-A118_gp45 PF10653.4 CCU98004.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein gp45 of Bacteriophage A118 PV-1 PF06637.6 CCU98004.1 - 1.8 7.0 8.6 3 6.3 6.0 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) NOT2_3_5 PF04153.13 CCU98005.1 - 7.8e-39 132.6 1.6 1e-38 132.2 1.1 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family ADH_zinc_N PF00107.21 CCU98006.1 - 1e-28 99.4 0.0 1.7e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCU98006.1 - 1.5e-10 42.0 0.5 5.7e-10 40.1 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCU98006.1 - 3.9e-10 39.4 0.1 8.3e-09 35.1 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain HupF_HypC PF01455.13 CCU98006.1 - 0.092 12.7 0.4 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 HupF/HypC family PGM_PMM_I PF02878.11 CCU98007.1 - 7e-37 125.9 0.0 1e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CCU98007.1 - 7.2e-27 93.6 0.0 1.4e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CCU98007.1 - 2.3e-17 63.2 0.1 5.6e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CCU98007.1 - 1.3e-09 37.9 0.0 3.1e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain tRNA_int_endo PF01974.12 CCU98008.1 - 3e-16 58.9 0.0 5.6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain SAPS PF04499.10 CCU98008.1 - 0.64 8.5 3.6 0.9 8.0 2.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PI3Ka PF00613.15 CCU98009.1 - 4e-47 159.7 0.8 6.6e-47 159.0 0.6 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CCU98009.1 - 3.4e-43 147.7 0.0 8.9e-41 139.8 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 CCU98009.1 - 0.00028 20.6 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Glycos_transf_1 PF00534.15 CCU98010.1 - 4.6e-16 58.7 0.0 8.7e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CCU98010.1 - 3.1e-07 30.6 0.0 1.2e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Mito_carr PF00153.22 CCU98011.1 - 2.3e-35 120.1 5.7 3.8e-16 58.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ETF PF01012.16 CCU98012.1 - 4.7e-35 120.7 1.1 6.3e-35 120.3 0.7 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain AAA_12 PF13087.1 CCU98013.1 - 2.7e-56 190.1 0.0 4.2e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCU98013.1 - 1.3e-55 188.5 0.0 3.4e-55 187.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCU98013.1 - 2.9e-11 42.9 3.2 7.7e-10 38.3 0.2 3.1 3 0 0 3 3 2 1 Part of AAA domain AAA_30 PF13604.1 CCU98013.1 - 2.8e-10 40.1 0.3 1.2e-05 25.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 CCU98013.1 - 4.1e-09 36.3 0.0 0.0048 16.4 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CCU98013.1 - 1.7e-05 24.9 0.0 0.0048 17.0 0.0 3.3 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 CCU98013.1 - 6.7e-05 22.1 0.1 0.00014 21.1 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CCU98013.1 - 0.00016 21.0 0.0 0.52 9.4 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.16 CCU98013.1 - 0.00033 20.0 0.0 0.0088 15.3 0.0 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CCU98013.1 - 0.00036 20.6 0.0 0.00088 19.3 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 CCU98013.1 - 0.00095 18.6 1.3 0.0028 17.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain UvrD_C PF13361.1 CCU98013.1 - 0.0016 17.9 0.0 0.52 9.7 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA PF00004.24 CCU98013.1 - 0.0016 18.6 0.0 0.0053 16.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCU98013.1 - 0.005 16.8 1.8 0.015 15.3 0.2 2.4 1 1 1 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.9 CCU98013.1 - 0.0054 16.3 0.0 0.2 11.2 0.0 2.5 2 0 0 2 2 2 1 Helicase DUF2075 PF09848.4 CCU98013.1 - 0.0064 15.5 0.0 2.3 7.0 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 CCU98013.1 - 0.0078 16.0 0.1 0.021 14.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 CCU98013.1 - 0.018 14.8 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 CCU98013.1 - 0.02 14.5 0.0 0.085 12.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain DEAD PF00270.24 CCU98013.1 - 0.028 13.9 0.0 0.31 10.4 0.0 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_17 PF13207.1 CCU98013.1 - 0.029 15.1 0.0 0.087 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CCU98013.1 - 0.034 13.0 0.0 0.19 10.6 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CCU98013.1 - 0.038 13.4 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 CCU98013.1 - 0.049 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 CCU98013.1 - 0.14 11.5 0.0 0.63 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain EF-hand_1 PF00036.27 CCU98014.1 - 1.2e-24 83.6 6.6 7.6e-08 31.1 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 CCU98014.1 - 2.8e-22 78.6 2.1 2.9e-13 49.7 0.3 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCU98014.1 - 3.3e-21 73.2 1.6 6.6e-06 25.5 0.0 5.2 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 CCU98014.1 - 2.9e-14 52.3 7.4 6.8e-05 22.4 0.5 4.4 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CCU98014.1 - 1.9e-12 45.9 9.4 0.00073 18.7 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.2 CCU98014.1 - 2e-09 37.1 2.6 0.0072 16.0 0.0 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CCU98014.1 - 0.00027 20.9 0.9 0.52 10.3 0.1 3.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CCU98014.1 - 0.00093 19.0 0.9 0.16 11.9 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_2 PF09068.6 CCU98014.1 - 0.0095 16.0 0.0 2.9 7.9 0.0 3.0 3 1 0 3 3 3 1 EF hand Mad3_BUB1_II PF08171.6 CCU98014.1 - 0.029 14.2 0.1 1.1 9.1 0.0 2.2 1 1 1 2 2 2 0 Mad3/BUB1 homology region 2 DUF1679 PF07914.6 CCU98014.1 - 0.091 11.3 0.1 1 7.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Glycos_transf_3 PF00591.16 CCU98015.1 - 5.1e-65 219.3 0.0 1.5e-63 214.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 CCU98015.1 - 0.0002 20.8 0.1 0.00043 19.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain EF-hand_7 PF13499.1 CCU98016.1 - 2.8e-09 36.9 0.1 7.1e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CCU98016.1 - 5.7e-07 28.8 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CCU98016.1 - 9.7e-06 24.5 0.0 0.019 14.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 CCU98016.1 - 6.3e-05 22.1 0.0 0.0089 15.3 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CCU98016.1 - 0.0014 18.1 0.0 0.066 12.8 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair ABC_membrane PF00664.18 CCU98017.1 - 3.9e-103 344.6 31.2 2e-57 194.7 9.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCU98017.1 - 1.1e-69 233.0 0.0 2.5e-35 121.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCU98017.1 - 2.3e-14 53.1 0.3 0.00025 20.3 0.0 4.1 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCU98017.1 - 5.2e-12 46.3 0.0 0.0083 16.1 0.0 4.2 4 0 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 CCU98017.1 - 7.3e-10 38.0 0.1 0.0017 17.0 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 CCU98017.1 - 1.5e-07 32.2 0.0 0.0067 17.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCU98017.1 - 2.1e-07 30.3 3.3 0.00057 19.3 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CCU98017.1 - 2.9e-07 30.6 2.7 0.015 15.2 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 CCU98017.1 - 4.1e-06 26.0 0.0 0.035 13.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 CCU98017.1 - 1.1e-05 25.2 2.2 0.18 11.7 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 CCU98017.1 - 1.3e-05 24.8 0.6 1.6 8.4 0.0 3.9 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCU98017.1 - 5.3e-05 23.3 3.3 0.47 10.6 0.3 3.9 2 2 0 2 2 2 2 AAA domain DUF87 PF01935.12 CCU98017.1 - 5.5e-05 23.0 0.1 0.023 14.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA PF00004.24 CCU98017.1 - 6.7e-05 23.1 0.7 3.7 7.7 0.1 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CCU98017.1 - 0.00012 21.5 1.0 0.28 10.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CCU98017.1 - 0.00017 21.2 0.2 3.8 7.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 CCU98017.1 - 0.00019 20.9 0.1 1.3 8.4 0.0 3.5 4 0 0 4 4 4 2 AAA-like domain AAA_18 PF13238.1 CCU98017.1 - 0.00021 21.5 0.0 0.24 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CCU98017.1 - 0.00066 19.2 0.0 0.56 9.6 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 CCU98017.1 - 0.00074 18.6 0.0 0.15 11.1 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 CCU98017.1 - 0.0033 17.3 0.0 1.6 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CCU98017.1 - 0.0064 16.3 0.0 9.1 6.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain G-alpha PF00503.15 CCU98017.1 - 0.0077 14.9 0.0 1.8 7.1 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_23 PF13476.1 CCU98017.1 - 0.0078 16.5 0.0 0.68 10.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCU98017.1 - 0.019 15.1 0.0 16 5.7 0.0 3.2 3 0 0 3 3 3 0 RNA helicase Rad17 PF03215.10 CCU98017.1 - 0.036 12.7 0.0 4.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 CCU98017.1 - 0.037 12.9 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 CCU98017.1 - 0.067 13.1 0.7 5.3 6.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CCU98017.1 - 0.1 12.2 0.1 9.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.15 CCU98017.1 - 0.13 11.8 0.2 20 4.7 0.0 3.0 3 0 0 3 3 3 0 Adenylylsulphate kinase PRK PF00485.13 CCU98017.1 - 0.15 11.6 0.0 11 5.5 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 CCU98017.1 - 0.19 11.6 0.0 30 4.6 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Formyl_trans_N PF00551.14 CCU98018.1 - 5.3e-33 114.0 0.1 9.4e-19 67.6 0.3 2.3 2 0 0 2 2 2 2 Formyl transferase Dynamin_N PF00350.18 CCU98019.1 - 3.8e-18 65.8 0.2 1.5e-17 63.9 0.1 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CCU98019.1 - 1.5e-10 41.0 0.0 2.1e-09 37.3 0.0 3.0 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCU98019.1 - 2.4e-08 33.6 3.4 1.2e-07 31.3 0.5 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CCU98019.1 - 2.6e-05 24.6 0.2 0.0028 18.1 0.2 2.7 1 1 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 CCU98019.1 - 0.00022 20.7 0.0 0.00051 19.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.14 CCU98019.1 - 0.00055 19.4 1.3 0.0024 17.3 0.9 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 CCU98019.1 - 0.0027 17.1 0.4 0.029 13.8 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family IIGP PF05049.8 CCU98019.1 - 0.014 14.2 0.1 0.045 12.5 0.0 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 CCU98019.1 - 0.014 14.6 0.2 6.6 5.9 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 CCU98019.1 - 0.02 14.8 0.8 0.075 13.0 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain MobB PF03205.9 CCU98019.1 - 0.032 13.9 0.1 0.27 10.9 0.0 2.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 CCU98019.1 - 0.041 12.9 0.2 0.14 11.1 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_17 PF13207.1 CCU98019.1 - 0.085 13.6 0.0 1.2 9.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CCU98019.1 - 0.097 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Abhydrolase_6 PF12697.2 CCU98020.1 - 1.1e-13 51.6 0.3 1.8e-13 50.9 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCU98020.1 - 2.6e-11 43.5 0.3 6.1e-11 42.3 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCU98020.1 - 8.1e-07 28.8 0.0 1.9e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CCU98020.1 - 0.00086 18.6 0.1 0.033 13.4 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family DUF1057 PF06342.7 CCU98020.1 - 0.018 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_4 PF08386.5 CCU98020.1 - 0.043 13.7 0.1 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein Lipase_3 PF01764.20 CCU98020.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.16 CCU98020.1 - 0.12 11.5 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ribosomal_L23eN PF03939.8 CCU98021.1 - 1.4e-20 73.0 8.7 1.4e-20 73.0 6.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 CCU98021.1 - 1.6e-18 66.4 1.7 3.1e-18 65.4 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 DUF3583 PF12126.3 CCU98021.1 - 0.081 11.9 0.4 0.097 11.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) RNase_PH PF01138.16 CCU98022.1 - 4.1e-17 62.7 0.0 6.9e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCU98022.1 - 5.6e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Aconitase PF00330.15 CCU98023.1 - 2.1e-177 590.2 0.0 2.5e-177 590.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCU98023.1 - 3e-41 140.6 0.0 5.5e-41 139.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ATP-synt_C PF00137.16 CCU98024.1 - 9.3e-29 99.1 30.9 8.5e-17 60.8 8.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Peptidase_M16_C PF05193.16 CCU98025.1 - 2.4e-43 147.9 0.0 4.9e-40 137.1 0.0 2.6 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCU98025.1 - 2.9e-38 130.9 0.9 1.8e-37 128.3 0.3 2.5 3 1 0 3 3 3 1 Insulinase (Peptidase family M16) B5 PF03484.10 CCU98025.1 - 0.049 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetase B5 domain zf-C3HC4_3 PF13920.1 CCU98026.1 - 9.6e-08 31.5 7.5 2.3e-05 23.9 2.8 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCU98026.1 - 9.8e-08 31.8 8.5 3.6e-07 30.0 4.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCU98026.1 - 2.7e-07 30.2 8.6 2.5e-06 27.2 3.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CCU98026.1 - 1.3e-06 27.9 4.9 1.3e-06 27.9 3.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCU98026.1 - 4.3e-05 23.1 8.8 0.00012 21.7 3.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CCU98026.1 - 0.009 15.7 5.2 0.009 15.7 3.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 CCU98026.1 - 0.59 9.9 3.2 25 4.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 CCU98026.1 - 2.1 7.9 7.2 1.1 8.8 0.6 2.8 3 0 0 3 3 3 0 P-11 zinc finger zf-C3HC4_4 PF15227.1 CCU98026.1 - 2.1 8.2 14.1 0.4 10.5 5.6 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Med6 PF04934.9 CCU98027.1 - 5.9e-13 48.5 0.0 8e-13 48.1 0.0 1.3 1 1 0 1 1 1 1 MED6 mediator sub complex component Peptidase_S24 PF00717.18 CCU98029.1 - 4.8e-10 38.9 0.1 1.9e-09 37.0 0.1 1.9 1 1 0 1 1 1 1 Peptidase S24-like PAP_central PF04928.12 CCU98031.1 - 4.5e-106 353.3 0.0 6.1e-106 352.8 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CCU98031.1 - 2.5e-41 140.8 0.0 4.1e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CCU98031.1 - 5.2e-09 36.3 0.0 1.4e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 CCU98031.1 - 0.076 13.0 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase beta palm DUF2797 PF10977.3 CCU98031.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) ENTH PF01417.15 CCU98032.1 - 4.2e-34 117.0 0.1 6.7e-34 116.4 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CCU98032.1 - 0.036 12.7 0.1 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 ANTH domain VHS PF00790.14 CCU98032.1 - 0.055 13.1 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 VHS domain Proteasome PF00227.21 CCU98033.1 - 9.9e-53 178.2 0.0 1.2e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCU98033.1 - 1.2e-14 53.3 0.0 2.7e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TRAPPC10 PF12584.3 CCU98034.1 - 2.6e-15 56.1 0.0 7.4e-15 54.7 0.0 1.7 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 RPAP1_C PF08620.5 CCU98035.1 - 1.3e-20 73.0 0.0 3.3e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 CCU98035.1 - 0.019 14.5 0.2 0.042 13.4 0.1 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal TFIID-18kDa PF02269.11 CCU98036.1 - 6.3e-19 67.5 0.2 6.3e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit Pyr_redox_2 PF07992.9 CCU98037.1 - 9.9e-47 159.4 0.7 1.6e-46 158.7 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CCU98037.1 - 8.9e-33 112.6 2.0 2.2e-32 111.3 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CCU98037.1 - 2.8e-22 78.8 4.0 3.3e-19 69.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCU98037.1 - 2.7e-15 56.9 0.4 1.7e-09 38.0 0.2 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCU98037.1 - 2.6e-09 36.6 0.3 7.4e-09 35.1 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCU98037.1 - 1.3e-08 34.1 3.5 1.2e-05 24.3 0.3 3.0 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.9 CCU98037.1 - 1.4e-07 30.3 3.7 0.0019 16.7 1.0 3.0 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.1 CCU98037.1 - 4.9e-05 22.3 0.0 0.00023 20.2 0.0 2.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 CCU98037.1 - 0.00019 20.6 4.5 0.2 10.6 0.8 2.4 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 CCU98037.1 - 0.00028 19.8 4.1 0.0011 17.9 0.7 2.7 3 1 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 CCU98037.1 - 0.00054 19.1 0.3 0.0015 17.6 0.2 1.7 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CCU98037.1 - 0.00077 19.4 2.4 0.0024 17.8 1.7 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCU98037.1 - 0.0032 16.4 0.5 0.0032 16.4 0.3 3.1 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 CCU98037.1 - 0.0042 17.3 0.1 1.1 9.5 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 CCU98037.1 - 0.048 13.3 0.0 0.048 13.3 0.0 2.5 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.27 CCU98038.1 - 3.7e-06 26.6 0.0 6.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat PQQ_3 PF13570.1 CCU98038.1 - 0.043 14.1 0.0 5.6 7.3 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain WD40 PF00400.27 CCU98039.1 - 1.9e-06 27.5 0.8 0.00089 19.0 0.1 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat CoaE PF01121.15 CCU98040.1 - 4.6e-54 182.5 0.2 5.7e-54 182.2 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 CCU98040.1 - 9.4e-06 25.9 0.2 3.9e-05 23.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCU98040.1 - 1.7e-05 25.6 0.0 3e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCU98040.1 - 0.0013 18.5 0.1 0.006 16.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain CcmH PF03918.9 CCU98040.1 - 0.013 14.5 0.2 0.025 13.5 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein TFIID_20kDa PF03847.8 CCU98041.1 - 7.3e-33 112.6 0.3 1.3e-32 111.8 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 CCU98041.1 - 0.004 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Methyltransf_26 PF13659.1 CCU98042.1 - 5.4e-07 29.6 0.0 7.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCU98042.1 - 1.5e-05 24.4 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Glyoxalase_4 PF13669.1 CCU98042.1 - 0.014 15.3 0.0 0.047 13.7 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CBF PF03914.12 CCU98043.1 - 7.3e-34 116.5 0.0 1.5e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 CBF/Mak21 family 4HBT_3 PF13622.1 CCU98044.1 - 0.019 14.7 1.2 0.022 14.5 0.8 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily WD40 PF00400.27 CCU98045.1 - 1.2e-07 31.3 0.0 0.0076 16.1 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Porphobil_deam PF01379.15 CCU98046.1 - 5.9e-70 234.5 0.0 1.3e-66 223.6 0.0 2.1 1 1 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CCU98046.1 - 4.2e-15 55.5 0.1 1.3e-14 54.0 0.1 1.9 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain PI3_PI4_kinase PF00454.22 CCU98047.1 - 8.2e-50 169.4 0.0 1.4e-49 168.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 CCU98047.1 - 1.1e-20 74.0 0.3 6.4e-20 71.4 0.2 2.2 1 1 0 1 1 1 1 FAT domain UME PF08064.8 CCU98047.1 - 1.3e-15 57.2 0.0 4.2e-15 55.6 0.0 2.0 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 CCU98047.1 - 2.4e-09 36.4 0.1 9.3e-09 34.5 0.0 2.1 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 CCU98047.1 - 0.00087 18.8 0.0 5.3 6.7 0.0 3.7 2 1 1 3 3 3 3 TPR repeat Oxysterol_BP PF01237.13 CCU98048.1 - 6.4e-83 278.1 0.0 7.2e-83 277.9 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Kinesin-relat_1 PF12711.2 CCU98048.1 - 0.0073 16.6 0.1 0.27 11.6 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor WD40 PF00400.27 CCU98049.1 - 1.2e-70 231.0 27.4 5.4e-08 32.4 0.0 12.2 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 CCU98049.1 - 2.3e-21 75.7 1.1 4.1e-21 74.9 0.7 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CCU98049.1 - 0.00015 20.0 1.1 0.0023 16.1 0.0 3.2 3 1 0 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCU98049.1 - 0.0004 19.2 0.0 2.2 6.9 0.0 4.1 3 1 0 4 4 4 2 Nup133 N terminal like Utp13 PF08625.6 CCU98049.1 - 0.0018 17.9 0.1 0.0068 16.0 0.1 1.8 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain Hira PF07569.6 CCU98049.1 - 0.05 12.7 0.0 0.77 8.9 0.0 2.6 2 0 0 2 2 2 0 TUP1-like enhancer of split PQQ_3 PF13570.1 CCU98049.1 - 1.3 9.3 7.8 1.5 9.1 0.0 4.9 7 0 0 7 7 7 0 PQQ-like domain SurE PF01975.12 CCU98050.1 - 3.4e-26 91.7 0.0 4.3e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Ribosomal_S8e PF01201.17 CCU98051.1 - 6.8e-49 165.3 0.7 8.1e-49 165.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e bZIP_1 PF00170.16 CCU98052.1 - 2.2e-07 30.7 9.7 2.2e-07 30.7 6.7 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CCU98052.1 - 6.5e-07 29.0 12.0 3.3e-05 23.6 5.9 2.3 1 1 1 2 2 2 2 Basic region leucine zipper CENP-F_leu_zip PF10473.4 CCU98052.1 - 0.041 13.7 11.7 0.063 13.1 8.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2730 PF10805.3 CCU98052.1 - 0.067 12.9 3.5 0.12 12.1 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) KBP_C PF12309.3 CCU98052.1 - 0.067 12.1 4.8 0.083 11.8 3.3 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal RabGAP-TBC PF00566.13 CCU98053.1 - 6e-58 195.8 0.5 6e-58 195.8 0.3 2.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Daxx PF03344.10 CCU98053.1 - 0.00045 18.8 46.1 0.00045 18.8 32.0 1.4 2 0 0 2 2 2 1 Daxx Family Oxysterol_BP PF01237.13 CCU98054.1 - 3.8e-114 380.8 0.0 4.6e-114 380.5 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Dopey_N PF04118.9 CCU98055.1 - 4e-103 344.4 0.0 3.3e-102 341.4 0.0 2.2 2 0 0 2 2 2 1 Dopey, N-terminal Vps51 PF08700.6 CCU98056.1 - 2.3e-14 52.9 0.5 4.3e-14 52.1 0.3 1.5 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 CCU98056.1 - 4.3e-06 26.6 0.2 1e-05 25.4 0.2 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 EXS PF03124.9 CCU98057.1 - 7e-87 291.6 23.4 9.1e-87 291.2 16.2 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CCU98057.1 - 7.3e-31 107.9 5.0 1.2e-30 107.2 3.5 1.3 1 0 0 1 1 1 1 SPX domain DUF3469 PF11952.3 CCU98057.1 - 0.1 12.3 0.1 0.39 10.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) Ribosomal_S15 PF00312.17 CCU98058.1 - 1e-16 60.4 0.0 2e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 SHQ1 PF04925.10 CCU98059.1 - 3.8e-26 91.7 0.2 8.3e-26 90.6 0.1 1.5 1 1 0 1 1 1 1 SHQ1 protein WD40 PF00400.27 CCU98060.1 - 2.7e-26 90.4 9.2 1.7e-07 30.8 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCU98060.1 - 0.058 12.1 0.1 0.9 8.2 0.0 2.7 2 1 2 4 4 4 0 Nup133 N terminal like DUF2890 PF11081.3 CCU98060.1 - 1.4 8.9 6.5 2.6 8.0 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 CCU98060.1 - 2.5 6.0 6.2 3.7 5.4 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_18 PF00704.23 CCU98061.1 - 5.4e-80 269.4 1.2 4.6e-54 184.1 0.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 DUF726 PF05277.7 CCU98062.1 - 8.9e-116 386.5 0.4 1.2e-115 386.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.15 CCU98062.1 - 0.00028 20.5 0.0 0.00065 19.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCU98062.1 - 0.0075 16.0 0.1 0.021 14.6 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family SRP14 PF02290.10 CCU98063.1 - 3e-19 68.7 0.0 6.4e-19 67.6 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Tn7_Tnp_TnsA_N PF08722.6 CCU98063.1 - 0.0098 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 TnsA endonuclease N terminal Mem_trans PF03547.13 CCU98064.1 - 4.4e-32 110.8 0.3 9.9e-32 109.6 0.2 1.6 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.20 CCU98065.1 - 2e-36 125.4 0.0 2.8e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98065.1 - 1.1e-26 93.4 0.0 1.5e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU98065.1 - 0.053 12.4 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Arm PF00514.18 CCU98066.1 - 0.048 13.5 0.1 0.048 13.5 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Npa1 PF11707.3 CCU98066.1 - 0.24 10.3 0.1 0.61 9.0 0.0 1.6 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal FAM74 PF15026.1 CCU98067.1 - 0.074 12.6 1.1 0.35 10.5 0.2 2.1 2 0 0 2 2 2 0 FAM74 protein TPR_16 PF13432.1 CCU98068.1 - 3.2e-12 46.7 6.1 2.6e-05 24.7 0.1 3.5 3 1 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCU98068.1 - 3.5e-12 45.7 3.6 3.9e-06 26.4 1.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CCU98068.1 - 4.1e-12 45.0 9.3 0.00014 21.4 0.3 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCU98068.1 - 1.8e-11 43.5 8.6 0.0018 18.7 0.2 5.0 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCU98068.1 - 2.2e-11 43.0 0.5 0.0023 18.0 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCU98068.1 - 6.8e-09 34.9 3.3 0.0031 17.0 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCU98068.1 - 1e-08 34.3 8.0 0.0092 15.6 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCU98068.1 - 1.7e-08 34.6 8.9 5.4e-05 23.4 0.4 4.5 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCU98068.1 - 1.5e-07 31.3 3.6 0.51 10.9 0.1 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CCU98068.1 - 3.2e-07 30.3 5.1 2.2e-05 24.4 0.8 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CCU98068.1 - 4.1e-05 23.0 5.0 0.17 11.7 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCU98068.1 - 6.2e-05 22.7 1.0 0.019 14.7 0.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCU98068.1 - 7.8e-05 22.5 11.8 0.7 9.8 0.3 4.4 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCU98068.1 - 0.00038 19.6 2.4 0.001 18.1 0.5 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 CCU98068.1 - 0.0037 17.5 6.8 2.9 8.5 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.5 CCU98068.1 - 0.0047 15.7 0.1 0.0063 15.3 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 CCU98068.1 - 0.02 15.0 0.1 0.15 12.2 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc5 PF12862.2 CCU98068.1 - 0.036 13.9 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 TPR_21 PF09976.4 CCU98068.1 - 0.038 13.9 0.2 13 5.7 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3808 PF10300.4 CCU98068.1 - 0.072 11.6 0.5 0.32 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) NARP1 PF12569.3 CCU98068.1 - 0.1 11.3 0.7 1.1 7.9 0.0 2.0 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 Metallophos PF00149.23 CCU98069.1 - 2.7e-43 147.7 0.1 3.5e-43 147.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Clp1 PF06807.9 CCU98070.1 - 8e-13 48.5 0.0 2.3e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.18 CCU98070.1 - 2.2e-05 24.4 0.0 0.041 13.8 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 CCU98070.1 - 0.00016 21.3 0.0 0.00088 18.9 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 CCU98070.1 - 0.0025 17.6 0.1 0.065 13.0 0.1 2.3 1 1 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 CCU98070.1 - 0.0065 16.4 0.0 0.058 13.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Pro_CA PF00484.14 CCU98070.1 - 0.01 15.8 0.0 0.36 10.8 0.0 2.3 2 0 0 2 2 2 0 Carbonic anhydrase AAA_17 PF13207.1 CCU98070.1 - 0.012 16.4 0.0 0.027 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCU98070.1 - 0.013 15.7 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 CCU98070.1 - 0.025 14.4 0.7 0.063 13.1 0.0 2.0 3 0 0 3 3 2 0 AAA domain DUF258 PF03193.11 CCU98070.1 - 0.028 13.6 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCU98070.1 - 0.038 13.9 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.13 CCU98070.1 - 0.072 12.0 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 CCU98070.1 - 0.085 12.3 0.0 0.92 8.9 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 CCU98070.1 - 0.088 12.3 0.0 0.51 9.9 0.0 2.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain Miro PF08477.8 CCU98070.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein NDUFA12 PF05071.11 CCU98071.1 - 4.2e-05 23.9 7.7 0.00016 22.0 1.7 2.8 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 GYF PF02213.11 CCU98071.1 - 0.00036 20.0 0.1 0.0013 18.3 0.0 2.0 1 1 0 1 1 1 1 GYF domain Transketolase_N PF00456.16 CCU98072.1 - 3.7e-131 436.8 0.0 5e-131 436.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CCU98072.1 - 3e-43 147.3 0.0 5.7e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCU98072.1 - 6e-13 48.8 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CCU98072.1 - 1.3e-05 24.2 0.1 0.0035 16.2 0.0 2.6 2 1 0 3 3 3 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 CCU98072.1 - 0.0018 17.0 0.0 0.0034 16.1 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component HMGL-like PF00682.14 CCU98073.1 - 6.2e-61 206.0 0.0 9.4e-61 205.4 0.0 1.3 1 0 0 1 1 1 1 HMGL-like TRAM_LAG1_CLN8 PF03798.11 CCU98073.1 - 2.8e-29 102.0 18.4 3.9e-29 101.6 12.8 1.2 1 0 0 1 1 1 1 TLC domain LeuA_dimer PF08502.5 CCU98073.1 - 1.2e-08 34.8 0.0 3.3e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain SET PF00856.23 CCU98074.1 - 0.0042 17.4 0.0 0.0092 16.3 0.0 1.6 1 0 0 1 1 1 1 SET domain Pex19 PF04614.7 CCU98075.1 - 1.1e-56 192.3 6.4 1.5e-56 191.8 4.4 1.2 1 0 0 1 1 1 1 Pex19 protein family DUF4456 PF14644.1 CCU98075.1 - 0.078 12.1 1.0 0.46 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) zf-DHHC PF01529.15 CCU98076.1 - 9.4e-31 106.5 7.5 9.4e-31 106.5 5.2 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 CCU98076.1 - 0.05 13.4 3.2 0.1 12.4 2.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Myosin_head PF00063.16 CCU98077.1 - 5.1e-229 761.8 0.1 8e-229 761.2 0.0 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CCU98077.1 - 5.5e-38 130.2 0.0 8.5e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 CCU98077.1 - 1.2e-11 43.7 0.2 2.5e-11 42.7 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCU98077.1 - 2.7e-11 42.8 0.4 1.3e-10 40.6 0.3 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CCU98077.1 - 1.4e-08 34.0 0.0 4.7e-08 32.3 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain AAA_17 PF13207.1 CCU98077.1 - 0.00021 22.0 0.1 0.001 19.8 0.0 2.3 2 0 0 2 2 1 1 AAA domain Hpr_kinase_C PF07475.7 CCU98077.1 - 0.0011 18.2 0.4 0.58 9.4 0.0 2.4 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain SH3_3 PF08239.6 CCU98077.1 - 0.0019 18.3 0.9 0.0042 17.2 0.2 1.9 2 0 0 2 2 1 1 Bacterial SH3 domain AAA_22 PF13401.1 CCU98077.1 - 0.0037 17.4 0.0 0.015 15.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 CCU98077.1 - 0.029 13.4 0.0 0.066 12.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 CCU98077.1 - 0.06 12.9 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 CCU98077.1 - 0.063 13.5 0.0 0.58 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain PurS PF02700.9 CCU98077.1 - 0.19 11.6 0.0 17 5.4 0.0 3.1 3 0 0 3 3 3 0 Phosphoribosylformylglycinamidine (FGAM) synthase Sigma54_activat PF00158.21 CCU98077.1 - 0.2 11.0 0.0 0.45 9.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 CCU98077.1 - 0.21 11.2 0.0 0.9 9.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PSK_trans_fac PF07704.6 CCU98077.1 - 0.33 11.6 3.2 3.9 8.2 0.0 3.3 2 1 1 3 3 3 0 Rv0623-like transcription factor IQ PF00612.22 CCU98077.1 - 0.66 9.7 15.5 0.18 11.5 3.2 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif Abhydrolase_2 PF02230.11 CCU98078.1 - 1.2e-53 181.8 0.0 1.4e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CCU98078.1 - 9.6e-12 44.8 0.0 1.4e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCU98078.1 - 2.6e-10 40.5 0.5 3.9e-10 40.0 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CCU98078.1 - 0.00018 20.9 0.4 0.00037 20.0 0.2 1.6 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.8 CCU98078.1 - 0.0007 19.0 0.0 0.0022 17.4 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase_phd PF10503.4 CCU98078.1 - 0.0011 18.2 0.0 0.0074 15.5 0.0 2.1 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 CCU98078.1 - 0.0018 17.9 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 CCU98078.1 - 0.0025 17.4 0.1 0.0093 15.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 CCU98078.1 - 0.047 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydro_lipase PF04083.11 CCU98078.1 - 0.082 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Cutinase PF01083.17 CCU98078.1 - 0.19 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Cutinase Fungal_trans PF04082.13 CCU98079.1 - 3.5e-18 65.4 1.5 7.6e-18 64.3 1.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCU98079.1 - 0.0075 16.1 4.8 0.015 15.1 3.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L34e PF01199.13 CCU98080.1 - 1e-35 121.8 5.9 1.3e-35 121.4 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.1 CCU98080.1 - 0.0055 16.3 0.1 0.0078 15.8 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c7 Phage_int_SAM_2 PF12834.2 CCU98080.1 - 0.13 12.6 1.0 8.6 6.8 0.0 2.5 2 1 0 2 2 2 0 Phage integrase, N-terminal FhuF_C PF11575.3 CCU98080.1 - 0.35 10.5 2.1 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Ribosomal_L6 PF00347.18 CCU98081.1 - 2.8e-22 78.9 0.1 4.5e-14 52.6 0.0 2.8 3 0 0 3 3 3 2 Ribosomal protein L6 NAD_kinase PF01513.16 CCU98082.1 - 2.7e-39 134.6 0.0 3.6e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase SKG6 PF08693.5 CCU98083.1 - 0.00018 20.7 0.3 0.00033 19.9 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 CCU98083.1 - 0.00067 18.0 0.0 0.00097 17.5 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 CCU98083.1 - 0.0033 17.0 0.2 0.0061 16.1 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain DUF4328 PF14219.1 CCU98083.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF1191 PF06697.7 CCU98083.1 - 0.023 13.5 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Adeno_E3_CR2 PF02439.10 CCU98083.1 - 0.048 13.1 0.1 0.078 12.5 0.1 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GST_N_3 PF13417.1 CCU98084.1 - 1.5e-11 44.3 0.0 5e-11 42.6 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCU98084.1 - 9.1e-10 38.3 0.0 1.8e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCU98084.1 - 9.5e-05 22.3 0.0 0.00021 21.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCU98084.1 - 0.0022 18.1 0.0 0.0039 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCU98084.1 - 0.047 14.1 0.0 0.13 12.7 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1_like PF12832.2 CCU98085.1 - 2.6e-15 55.9 1.4 2.6e-15 55.9 1.0 3.0 4 1 1 5 5 5 1 MFS_1 like family DUF373 PF04123.8 CCU98085.1 - 4.6 6.1 7.1 0.51 9.2 2.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF373) SMI1_KNR4 PF09346.5 CCU98086.1 - 5.8e-23 81.3 0.0 9.4e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Glyco_hydro_63 PF03200.11 CCU98087.1 - 9.1e-217 721.6 0.7 4.5e-215 716.0 0.5 2.0 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 CCU98087.1 - 2.1e-05 23.3 0.1 3.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 CCU98087.1 - 0.0011 17.8 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase SOG2 PF10428.4 CCU98088.1 - 6.9e-66 222.7 0.3 1.1e-65 222.0 0.2 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein SH2_2 PF14633.1 CCU98089.1 - 5.6e-68 228.3 0.0 1.1e-67 227.4 0.0 1.4 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 CCU98089.1 - 7e-24 84.1 0.1 7e-24 84.1 0.1 2.8 3 0 0 3 3 3 1 Death-like domain of SPT6 YqgF PF14639.1 CCU98089.1 - 5.3e-23 81.2 0.0 2.5e-22 79.0 0.0 2.1 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 CCU98089.1 - 1.4e-19 70.0 0.0 3.9e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 CCU98089.1 - 2.3e-14 53.3 24.8 2.3e-14 53.3 17.2 3.3 2 1 1 3 3 3 2 Acidic N-terminal SPT6 HTH_44 PF14641.1 CCU98089.1 - 7.7e-11 42.0 0.0 1.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 CCU98089.1 - 0.0007 19.3 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 CCU98089.1 - 0.0027 17.7 0.1 0.011 15.7 0.0 2.2 2 0 0 2 2 2 1 S1 RNA binding domain SET PF00856.23 CCU98090.1 - 2.5e-10 40.8 0.1 7.6e-10 39.3 0.1 1.9 1 1 0 1 1 1 1 SET domain AAA PF00004.24 CCU98091.1 - 2e-45 154.2 0.1 1.1e-44 151.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCU98091.1 - 7.8e-09 35.3 0.1 2.4e-08 33.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCU98091.1 - 1.1e-07 31.9 0.0 2.8e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCU98091.1 - 1.2e-06 28.6 0.3 0.00045 20.3 0.2 3.0 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CCU98091.1 - 1.6e-06 28.1 0.0 6.7e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 CCU98091.1 - 6.6e-06 25.2 0.2 1.6e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CCU98091.1 - 0.00023 21.1 0.1 0.00084 19.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCU98091.1 - 0.00026 20.0 0.0 0.00053 19.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCU98091.1 - 0.00041 20.0 0.1 0.0012 18.5 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCU98091.1 - 0.00066 19.3 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCU98091.1 - 0.00069 19.5 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CCU98091.1 - 0.0011 18.6 0.0 0.0043 16.7 0.0 2.1 2 0 0 2 2 1 1 NTPase Arch_ATPase PF01637.13 CCU98091.1 - 0.0012 18.6 0.2 0.091 12.4 0.0 2.7 2 1 1 3 3 3 1 Archaeal ATPase NACHT PF05729.7 CCU98091.1 - 0.0013 18.4 0.1 0.034 13.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 CCU98091.1 - 0.0018 19.0 0.0 0.0047 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CCU98091.1 - 0.0018 18.4 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 CCU98091.1 - 0.0025 17.6 0.0 0.0076 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCU98091.1 - 0.0041 17.4 0.0 0.011 15.9 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CCU98091.1 - 0.0042 16.5 1.1 0.051 12.9 0.1 2.3 1 1 1 2 2 2 1 AAA domain UPF0079 PF02367.12 CCU98091.1 - 0.0048 16.5 0.0 0.018 14.6 0.0 1.8 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 CCU98091.1 - 0.0056 16.2 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CCU98091.1 - 0.0057 15.8 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CCU98091.1 - 0.0058 16.0 0.0 0.024 14.0 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_11 PF13086.1 CCU98091.1 - 0.0062 16.1 0.0 0.029 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCU98091.1 - 0.0065 15.5 0.2 0.014 14.4 0.0 1.6 2 0 0 2 2 1 1 Zeta toxin AAA_24 PF13479.1 CCU98091.1 - 0.012 15.2 0.1 0.028 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CCU98091.1 - 0.014 14.1 0.0 0.024 13.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_23 PF13476.1 CCU98091.1 - 0.022 15.0 1.0 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 CCU98091.1 - 0.022 14.3 0.0 0.082 12.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 CCU98091.1 - 0.036 14.0 0.2 1.1 9.2 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CCU98091.1 - 0.053 12.3 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AFG1_ATPase PF03969.11 CCU98091.1 - 0.062 12.1 0.0 0.14 10.9 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase KaiC PF06745.8 CCU98091.1 - 0.063 12.3 0.2 0.44 9.6 0.0 2.4 3 0 0 3 3 3 0 KaiC DAP3 PF10236.4 CCU98091.1 - 0.065 12.1 0.2 0.45 9.3 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Sigma54_activat PF00158.21 CCU98091.1 - 0.082 12.3 0.3 1.4 8.3 0.0 2.6 3 1 0 3 3 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 CCU98091.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RIG-I_C-RD PF11648.3 CCU98091.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of RIG-I AAA_10 PF12846.2 CCU98091.1 - 0.23 10.8 2.0 1.4 8.2 0.1 2.9 2 1 0 4 4 4 0 AAA-like domain P5CR_dimer PF14748.1 CCU98092.1 - 3.5e-38 129.8 4.0 7.7e-38 128.7 1.8 2.1 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CCU98092.1 - 5e-13 49.2 0.6 3.1e-10 40.3 0.0 2.7 2 1 1 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 CCU98092.1 - 0.014 14.7 0.1 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ATP-gua_Ptrans PF00217.14 CCU98092.1 - 0.094 12.0 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain CENP-F_leu_zip PF10473.4 CCU98093.1 - 0.00025 20.9 26.5 0.0063 16.3 10.7 2.4 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 CCU98093.1 - 0.00035 20.5 13.2 0.00035 20.5 9.2 2.6 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 CCU98093.1 - 0.00054 19.5 14.0 0.081 12.4 1.5 2.3 2 0 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 CCU98093.1 - 0.0016 18.6 6.6 0.081 13.1 0.3 3.8 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein Myosin_tail_1 PF01576.14 CCU98093.1 - 0.0022 15.7 21.2 0.0035 15.1 14.7 1.2 1 0 0 1 1 1 1 Myosin tail AAA_13 PF13166.1 CCU98093.1 - 0.011 14.2 9.3 0.015 13.7 6.5 1.1 1 0 0 1 1 1 0 AAA domain Striatin PF08232.7 CCU98093.1 - 0.016 15.5 10.5 0.016 15.5 7.2 2.7 2 1 1 3 3 2 0 Striatin family BRE1 PF08647.6 CCU98093.1 - 0.025 14.5 13.7 0.071 13.0 2.5 2.9 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.6 CCU98093.1 - 0.034 13.9 24.8 0.23 11.2 10.0 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ERM PF00769.14 CCU98093.1 - 0.047 13.2 24.1 0.09 12.3 16.7 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Baculo_PEP_C PF04513.7 CCU98093.1 - 0.075 12.8 7.0 0.054 13.3 1.7 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2681 PF10883.3 CCU98093.1 - 0.29 11.3 10.7 0.84 9.8 0.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2681) Tropomyosin PF00261.15 CCU98093.1 - 0.36 9.8 20.5 0.018 14.1 4.7 2.4 1 1 1 2 2 2 0 Tropomyosin APG6 PF04111.7 CCU98093.1 - 0.41 9.6 25.3 0.053 12.5 5.8 2.2 1 1 0 2 2 2 0 Autophagy protein Apg6 Tup_N PF08581.5 CCU98093.1 - 0.45 10.7 19.0 2.1 8.5 4.2 3.5 1 1 2 3 3 3 0 Tup N-terminal GAS PF13851.1 CCU98093.1 - 0.5 9.5 22.1 1.1 8.4 5.1 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 CCU98093.1 - 0.55 10.2 31.2 2.6 8.0 11.3 3.3 2 1 1 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RTBV_P46 PF06216.6 CCU98093.1 - 0.6 8.8 9.7 2 7.1 1.3 2.1 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein TMF_DNA_bd PF12329.3 CCU98093.1 - 0.65 9.8 19.1 0.49 10.2 0.7 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding HOOK PF05622.7 CCU98093.1 - 0.67 7.6 22.9 0.25 9.1 11.5 1.7 1 1 1 2 2 2 0 HOOK protein RasGAP_C PF03836.10 CCU98093.1 - 0.68 9.6 7.0 0.4 10.3 2.9 2.0 1 1 1 2 2 2 0 RasGAP C-terminus HAP1_N PF04849.8 CCU98093.1 - 0.72 8.7 24.6 0.39 9.6 1.9 2.4 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DASH_Dad2 PF08654.5 CCU98093.1 - 0.77 9.7 6.2 1.1 9.3 0.2 3.2 1 1 1 3 3 3 0 DASH complex subunit Dad2 Med10 PF09748.4 CCU98093.1 - 0.81 9.5 6.8 0.55 10.0 1.2 3.0 2 1 1 3 3 3 0 Transcription factor subunit Med10 of Mediator complex Filament PF00038.16 CCU98093.1 - 0.86 9.0 27.1 4.2 6.7 7.0 3.0 1 1 2 3 3 3 0 Intermediate filament protein DUF1049 PF06305.6 CCU98093.1 - 0.92 9.0 4.1 11 5.6 0.0 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1049) Med9 PF07544.8 CCU98093.1 - 1.4 8.6 8.7 0.3 10.8 0.1 3.2 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4140 PF13600.1 CCU98093.1 - 1.5 9.2 23.8 0.55 10.6 2.4 4.5 1 1 2 3 3 2 0 N-terminal domain of unknown function (DUF4140) EMP24_GP25L PF01105.19 CCU98093.1 - 1.8 8.2 7.7 0.11 12.1 1.0 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Syntaxin-6_N PF09177.6 CCU98093.1 - 1.9 8.9 14.9 15 6.0 1.9 3.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Metal_resist PF13801.1 CCU98093.1 - 2.3 8.2 16.9 0.15 12.0 5.1 2.9 2 0 0 2 2 2 0 Heavy-metal resistance BLOC1_2 PF10046.4 CCU98093.1 - 2.3 8.4 7.4 9.1 6.4 0.9 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.17 CCU98093.1 - 2.4 8.2 13.9 0.38 10.7 1.3 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.5 CCU98093.1 - 2.5 8.2 12.1 0.13 12.3 3.0 2.6 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family Cortex-I_coil PF09304.5 CCU98093.1 - 2.5 8.2 20.0 0.035 14.1 5.4 2.9 1 1 2 3 3 1 0 Cortexillin I, coiled coil DUF1664 PF07889.7 CCU98093.1 - 3.1 7.6 11.4 2.2 8.0 1.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.15 CCU98093.1 - 3.2 7.5 18.5 1 9.1 0.7 4.1 3 1 1 4 4 4 0 Prefoldin subunit Surfac_D-trimer PF09006.6 CCU98093.1 - 3.3 7.4 7.7 25 4.7 0.0 4.2 3 1 1 4 4 3 0 Lung surfactant protein D coiled-coil trimerisation M_domain PF12938.2 CCU98093.1 - 3.8 7.2 8.6 2.2 8.0 2.8 2.5 1 1 2 3 3 2 0 M domain of GW182 Bap31 PF05529.7 CCU98093.1 - 4 6.8 11.1 0.099 12.0 1.4 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF641 PF04859.7 CCU98093.1 - 4.1 7.1 16.6 1.9 8.2 3.3 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF4200 PF13863.1 CCU98093.1 - 4.3 7.2 21.6 7 6.6 7.0 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 CCU98093.1 - 5 6.2 14.1 0.59 9.2 2.5 2.3 2 1 1 3 3 2 0 Reovirus sigma C capsid protein Mnd1 PF03962.10 CCU98093.1 - 6.1 6.4 25.8 4.4 6.9 2.8 3.2 1 1 2 3 3 3 0 Mnd1 family DUF342 PF03961.8 CCU98093.1 - 6.2 5.1 11.5 1.4 7.2 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DASH_Dad3 PF08656.5 CCU98093.1 - 7.3 6.3 8.5 20 4.9 0.1 3.5 2 1 1 3 3 3 0 DASH complex subunit Dad3 DUF904 PF06005.7 CCU98093.1 - 7.5 6.9 25.5 0.11 12.8 1.4 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF904) IncA PF04156.9 CCU98093.1 - 7.7 6.0 34.5 2.8 7.4 10.8 2.8 1 1 1 2 2 2 0 IncA protein cwf18 PF08315.7 CCU98093.1 - 8 6.9 11.3 0.39 11.1 2.3 2.3 1 1 1 2 2 2 0 cwf18 pre-mRNA splicing factor DUF3450 PF11932.3 CCU98093.1 - 8.7 5.5 23.3 0.079 12.2 4.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Sec7_N PF12783.2 CCU98094.1 - 4.6e-23 81.4 1.5 2.3e-22 79.2 0.4 2.7 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CCU98094.1 - 5.4e-05 22.6 0.5 0.00052 19.4 0.0 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DUF2828 PF11443.3 CCU98094.1 - 0.034 12.3 0.0 0.069 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) KOW PF00467.24 CCU98095.1 - 6.2e-08 32.0 0.5 6.2e-08 32.0 0.4 2.3 2 0 0 2 2 2 1 KOW motif Arf PF00025.16 CCU98096.1 - 5.7e-35 120.1 0.0 3.3e-34 117.6 0.0 1.8 1 1 1 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 CCU98096.1 - 0.011 16.2 0.0 0.018 15.5 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 CCU98096.1 - 0.083 12.1 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pkinase PF00069.20 CCU98097.1 - 7e-59 199.0 0.0 1.1e-58 198.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98097.1 - 2.7e-22 79.1 0.0 3.8e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU98097.1 - 0.00012 21.1 0.0 0.00022 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCU98097.1 - 0.0012 18.6 0.1 0.0055 16.4 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCU98097.1 - 0.016 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase UreD PF01774.12 CCU98098.1 - 3.7e-51 173.5 0.0 5.1e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 UreD urease accessory protein Fcf1 PF04900.7 CCU98099.1 - 6.2e-40 135.3 1.8 1.1e-39 134.6 0.6 1.8 2 0 0 2 2 2 1 Fcf1 SUI1 PF01253.17 CCU98100.1 - 3.5e-28 97.2 0.3 5.5e-28 96.6 0.2 1.3 1 1 0 1 1 1 1 Translation initiation factor SUI1 rRNA_processing PF08524.6 CCU98101.1 - 0.00015 21.5 7.7 0.00049 19.9 5.3 1.8 1 1 0 1 1 1 1 rRNA processing Cep57_MT_bd PF06657.8 CCU98102.1 - 2.3e-12 46.6 12.7 1.5e-10 40.8 0.9 4.4 4 1 1 5 5 5 2 Centrosome microtubule-binding domain of Cep57 EzrA PF06160.7 CCU98102.1 - 0.017 13.3 2.9 0.27 9.3 0.3 2.4 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA FlxA PF14282.1 CCU98102.1 - 0.11 12.4 0.8 0.45 10.4 0.3 2.3 2 1 0 2 2 2 0 FlxA-like protein SWIRM PF04433.12 CCU98102.1 - 0.12 12.5 0.1 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 SWIRM domain DUF812 PF05667.6 CCU98102.1 - 0.12 10.8 6.4 0.029 12.9 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF812) IncA PF04156.9 CCU98102.1 - 2.3 7.7 13.1 0.91 9.0 0.2 3.2 2 1 0 3 3 3 0 IncA protein SlyX PF04102.7 CCU98102.1 - 5.5 7.4 12.0 0.35 11.2 0.3 4.2 4 1 1 5 5 5 0 SlyX ADIP PF11559.3 CCU98102.1 - 7.2 6.4 11.9 1.2 9.0 0.4 3.7 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Glycos_transf_1 PF00534.15 CCU98103.1 - 6e-28 97.4 0.0 1.5e-27 96.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CCU98103.1 - 2.1e-08 34.1 0.5 5.1e-07 29.5 0.3 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CCU98103.1 - 9.3e-08 32.3 4.7 9.3e-08 32.3 3.3 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CCU98103.1 - 8.4e-07 29.2 0.1 8.5e-06 25.9 0.1 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CCU98103.1 - 3.3e-05 24.0 0.0 9.4e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Mito_carr PF00153.22 CCU98104.1 - 5.6e-19 67.6 0.0 3.1e-07 30.0 0.0 5.1 4 1 0 4 4 4 4 Mitochondrial carrier protein APC_CDC26 PF10471.4 CCU98104.1 - 3.6e-05 24.4 0.1 6.6e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Nol1_Nop2_Fmu PF01189.12 CCU98105.1 - 4.1e-34 118.2 0.0 1.9e-18 66.8 0.0 3.8 2 1 1 3 3 3 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CCU98105.1 - 0.007 16.3 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CCU98105.1 - 0.015 15.3 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CCU98105.1 - 0.075 13.6 0.0 0.22 12.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Flavokinase PF01687.12 CCU98105.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Riboflavin kinase CTDII PF01556.13 CCU98106.1 - 3.6e-27 94.0 0.1 1.1e-20 73.2 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 CCU98106.1 - 4.2e-24 84.0 2.7 6.7e-24 83.4 1.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CCU98106.1 - 9e-12 44.8 17.4 2.1e-11 43.7 11.7 1.9 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 CCU98106.1 - 5.3 6.7 6.6 15 5.2 4.6 1.7 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family LMWPc PF01451.16 CCU98107.1 - 6.8e-25 87.9 0.0 7.9e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Sec1 PF00995.18 CCU98108.1 - 7.9e-140 467.1 0.0 8.9e-140 466.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family GYF PF02213.11 CCU98109.1 - 1e-11 44.2 0.1 2.7e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 GYF domain 4HBT_3 PF13622.1 CCU98109.1 - 1.2e-11 44.8 1.1 1.2e-11 44.8 0.7 4.4 2 1 1 4 4 4 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 CCU98109.1 - 0.00038 20.0 0.0 0.0021 17.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA thioesterase RRP7 PF12923.2 CCU98109.1 - 0.0083 16.1 0.3 1.5 8.8 0.1 2.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Hist_deacetyl PF00850.14 CCU98110.1 - 1.1e-81 274.5 0.0 1.6e-81 273.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Dehydratase_hem PF13816.1 CCU98110.1 - 0.095 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase CDC45 PF02724.9 CCU98110.1 - 8.6 4.2 6.4 11 3.8 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein ATP-synt_F PF01990.12 CCU98111.1 - 5.8e-27 93.9 0.1 7.3e-27 93.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PTH2 PF01981.11 CCU98112.1 - 3.2e-27 94.5 1.3 8.6e-27 93.1 0.5 1.7 1 1 1 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 NUDIX PF00293.23 CCU98113.1 - 5.7e-15 55.1 0.1 1.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.8 CCU98113.1 - 1.3e-11 44.2 0.1 5.4e-11 42.2 0.0 1.9 1 1 0 1 1 1 1 Dcp2, box A domain BATS PF06968.8 CCU98114.1 - 2.5e-25 88.1 0.0 5.7e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 CCU98114.1 - 8e-16 58.6 0.1 1.8e-15 57.5 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily DUF900 PF05990.7 CCU98115.1 - 0.034 13.4 0.1 0.32 10.2 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PPR_2 PF13041.1 CCU98117.1 - 4e-08 33.1 0.0 0.02 14.8 0.0 5.7 7 0 0 7 7 7 1 PPR repeat family PPR_3 PF13812.1 CCU98117.1 - 1.5e-05 24.8 10.6 0.6 10.5 0.0 7.5 6 1 1 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 CCU98117.1 - 0.00045 19.9 0.2 7.3 6.8 0.0 5.3 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.2 CCU98117.1 - 0.6 9.6 9.0 0.89 9.0 0.0 4.9 6 0 0 6 6 6 0 PPR repeat EXOSC1 PF10447.4 CCU98118.1 - 2.5e-27 94.6 0.0 3.8e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 CCU98118.1 - 0.0069 15.6 2.0 0.0071 15.6 0.1 2.1 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 CCU98118.1 - 0.059 13.4 0.0 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 S1 RNA binding domain LTV PF04180.9 CCU98119.1 - 1.7e-28 100.3 4.6 1.7e-22 80.5 4.0 3.4 3 1 0 3 3 3 2 Low temperature viability protein RR_TM4-6 PF06459.7 CCU98119.1 - 0.1 12.5 4.2 0.22 11.4 2.9 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WES_acyltransf PF03007.11 CCU98120.1 - 4.2e-14 52.7 0.0 6.4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.8 CCU98120.1 - 0.00018 21.2 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) 2-oxoacid_dh PF00198.18 CCU98121.1 - 8.5e-80 267.3 0.6 1.2e-79 266.8 0.4 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CCU98121.1 - 1.5e-18 66.1 0.4 3.1e-18 65.1 0.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CCU98121.1 - 2.4e-13 49.4 0.3 4.6e-13 48.5 0.2 1.5 1 0 0 1 1 1 1 e3 binding domain CDC45 PF02724.9 CCU98121.1 - 0.012 13.6 2.8 0.016 13.3 1.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 CCU98121.1 - 0.02 14.2 11.9 0.039 13.3 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 CCU98121.1 - 0.061 13.2 3.4 0.11 12.4 2.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.10 CCU98121.1 - 0.11 11.1 1.3 0.13 10.9 0.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.12 CCU98121.1 - 0.22 11.2 5.4 0.42 10.3 3.8 1.4 1 0 0 1 1 1 0 DDHD domain PMSI1 PF15322.1 CCU98121.1 - 0.39 9.7 5.0 0.69 8.9 3.5 1.4 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative RR_TM4-6 PF06459.7 CCU98121.1 - 0.53 10.1 9.5 0.94 9.3 6.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2413 PF10310.4 CCU98121.1 - 2.6 6.7 15.9 4.3 6.0 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1767 PF08585.7 CCU98122.1 - 0.063 13.5 0.9 0.74 10.1 0.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1767) CMV_1a PF12467.3 CCU98123.1 - 2.2 8.6 7.1 0.89 9.8 2.7 1.9 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family BRF1 PF07741.8 CCU98123.1 - 2.4 8.4 6.5 13 6.0 2.5 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF2217 PF10265.4 CCU98123.1 - 2.4 6.8 5.1 3 6.4 3.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) FAM60A PF15396.1 CCU98123.1 - 2.6 7.7 6.9 5.2 6.7 4.8 1.6 1 1 0 1 1 1 0 Protein Family FAM60A RNA_pol_Rpb2_6 PF00562.23 CCU98125.1 - 2.6e-124 414.8 0.3 4.5e-124 414.1 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCU98125.1 - 4.4e-64 215.1 0.0 7.4e-64 214.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCU98125.1 - 7.1e-49 165.8 0.0 1.3e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCU98125.1 - 1e-27 96.2 0.1 2.9e-27 94.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CCU98125.1 - 3.8e-26 90.6 0.2 1.2e-25 89.0 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CCU98125.1 - 2.1e-23 81.8 0.1 4.5e-23 80.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CCU98125.1 - 3.5e-19 68.5 0.2 8.3e-19 67.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 CWC25 PF12542.3 CCU98126.1 - 3.1e-23 82.0 1.8 3.1e-23 82.0 1.2 4.0 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.4 CCU98126.1 - 8.8e-15 54.4 17.5 8.8e-15 54.4 12.2 4.0 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR MFS_1 PF07690.11 CCU98127.1 - 2.1e-31 108.9 29.9 2.6e-31 108.6 20.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Lung_7-TM_R PF06814.8 CCU98128.1 - 2.8e-43 147.9 25.9 7.4e-43 146.5 17.9 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF2636 PF11120.3 CCU98128.1 - 0.16 11.4 1.0 0.37 10.3 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) Lung_7-TM_R PF06814.8 CCU98129.1 - 0.14 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Lung seven transmembrane receptor Homeobox_KN PF05920.6 CCU98130.1 - 7.8e-12 44.7 0.2 2.1e-11 43.3 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Ustilago_mating PF05722.7 CCU98130.1 - 2.3e-05 23.8 0.6 5.3e-05 22.6 0.4 1.7 1 1 0 1 1 1 1 Ustilago B locus mating-type protein Arg_repressor PF01316.16 CCU98130.1 - 0.0057 16.1 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain Homeobox PF00046.24 CCU98131.1 - 9e-08 31.6 0.2 5e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CCU98131.1 - 0.14 11.9 0.4 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 Homeobox KN domain AA_permease_2 PF13520.1 CCU98132.1 - 1.4e-70 237.9 37.7 1.4e-70 237.9 26.1 1.4 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 CCU98132.1 - 1.2e-18 66.7 31.4 1.2e-18 66.7 21.8 1.6 2 0 0 2 2 2 1 Amino acid permease Aldo_ket_red PF00248.16 CCU98133.1 - 3.6e-46 157.2 0.0 4.1e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HA2 PF04408.18 CCU98134.1 - 1.4e-17 63.6 0.2 1.4e-17 63.6 0.1 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCU98134.1 - 1e-10 41.2 0.1 2.9e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCU98134.1 - 1.2e-09 37.9 0.2 3.1e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 CCU98134.1 - 1.4e-09 37.7 0.0 4.8e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 CCU98134.1 - 3.8e-08 33.5 0.2 3.3e-07 30.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 CCU98134.1 - 0.0096 16.2 0.9 0.066 13.5 0.0 2.8 3 0 0 3 3 3 1 ABC transporter NB-ARC PF00931.17 CCU98134.1 - 0.035 12.9 0.0 0.068 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 CCU98134.1 - 0.051 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 CCU98134.1 - 0.079 12.5 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2088 PF09861.4 CCU98134.1 - 0.11 11.5 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2088) AAA_23 PF13476.1 CCU98134.1 - 0.25 11.6 0.6 10 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain CS PF04969.11 CCU98136.1 - 0.00035 21.0 0.0 0.00081 19.8 0.0 1.7 1 1 0 1 1 1 1 CS domain DUF2326 PF10088.4 CCU98136.1 - 0.19 11.3 0.1 0.42 10.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2326) Acetyltransf_8 PF13523.1 CCU98137.1 - 1.3e-45 154.9 0.1 2e-45 154.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain K_oxygenase PF13434.1 CCU98138.1 - 2.1e-92 309.6 0.0 3e-92 309.1 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 CCU98138.1 - 9.5e-08 32.3 0.0 2.7e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCU98138.1 - 1.7e-07 31.1 0.1 2.4e-06 27.4 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Sec3_C PF09763.4 CCU98139.1 - 4.1e-131 438.3 0.0 1.7e-77 261.2 0.0 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec3 Lactamase_B_2 PF12706.2 CCU98139.1 - 1.6e-28 99.5 0.2 3.3e-28 98.5 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sec3-PIP2_bind PF15277.1 CCU98139.1 - 5.3e-11 42.2 0.0 9e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Lactamase_B_3 PF13483.1 CCU98139.1 - 4.5e-06 26.4 0.0 1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ald_Xan_dh_C2 PF02738.13 CCU98139.1 - 0.083 11.2 1.3 0.13 10.5 0.9 1.2 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase TnpB_IS66 PF05717.8 CCU98139.1 - 0.13 11.7 0.0 0.53 9.7 0.0 2.0 2 0 0 2 2 2 0 IS66 Orf2 like protein Rav1p_C PF12234.3 CCU98141.1 - 1.2e-86 291.3 3.1 5.3e-78 262.7 0.4 2.1 2 0 0 2 2 2 2 RAVE protein 1 C terminal Nucleoporin_N PF08801.6 CCU98141.1 - 0.038 12.7 0.0 6.6 5.3 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like Aminotran_1_2 PF00155.16 CCU98142.1 - 3.1e-92 309.3 0.0 3.6e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HHH_8 PF14716.1 CCU98143.1 - 6.2e-14 51.9 0.0 1.1e-10 41.5 0.0 2.8 2 1 1 3 3 3 2 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 CCU98143.1 - 2.1e-11 43.2 0.0 1.3e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 CCU98143.1 - 9.7e-09 35.2 0.0 0.0001 22.3 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.18 CCU98143.1 - 3.1e-07 29.7 0.0 0.00017 21.0 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_2 PF12826.2 CCU98143.1 - 3.6e-07 29.9 0.0 4.3e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif Cdd1 PF11731.3 CCU98143.1 - 0.00011 22.0 0.0 0.089 12.7 0.0 2.3 1 1 1 2 2 2 2 Pathogenicity locus HHH_3 PF12836.2 CCU98143.1 - 0.0015 18.4 0.0 0.047 13.6 0.0 2.3 1 1 0 1 1 1 1 Helix-hairpin-helix motif DUF3701 PF12482.3 CCU98143.1 - 0.0017 18.0 0.2 1.5 8.5 0.0 2.7 2 1 0 2 2 2 2 Phage integrase protein Peptidase_M28 PF04389.12 CCU98144.1 - 2.8e-27 95.5 0.0 4.1e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CCU98144.1 - 9.5e-08 31.7 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 S1 PF00575.18 CCU98145.1 - 3.1e-47 158.5 10.0 1.1e-15 57.4 0.1 8.8 8 0 0 8 8 8 7 S1 RNA binding domain TPR_19 PF14559.1 CCU98145.1 - 2e-08 34.4 0.0 0.17 12.2 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCU98145.1 - 4.7e-08 33.4 1.3 0.079 13.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCU98145.1 - 1.1e-07 31.8 3.4 0.02 15.4 0.0 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat Suf PF05843.9 CCU98145.1 - 2.7e-05 24.0 5.5 0.0057 16.4 0.1 3.8 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_12 PF13424.1 CCU98145.1 - 0.00022 21.0 0.8 1.3 9.0 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCU98145.1 - 0.0082 16.5 1.6 0.17 12.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCU98145.1 - 0.034 14.0 3.5 13 6.0 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ANTH PF07651.11 CCU98146.1 - 1.2e-69 234.1 1.2 2.1e-69 233.3 0.0 2.0 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 CCU98146.1 - 2.8e-61 205.9 8.6 2.8e-61 205.9 6.0 4.1 4 0 0 4 4 4 1 I/LWEQ domain PC-Esterase PF13839.1 CCU98146.1 - 4.4e-08 33.2 0.2 1.6e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p ENTH PF01417.15 CCU98146.1 - 3.3e-05 23.7 0.0 0.00015 21.6 0.0 2.2 1 0 0 1 1 1 1 ENTH domain Arrestin_N PF00339.24 CCU98147.1 - 0.00056 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DSHCT PF08148.7 CCU98148.1 - 3.4e-58 195.8 0.3 7.7e-58 194.6 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CCU98148.1 - 1.6e-09 37.4 0.1 3.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 CCU98148.1 - 4.1e-08 32.7 0.1 2.9e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 rRNA-processing arch domain Helicase_C PF00271.26 CCU98148.1 - 1.4e-05 24.8 0.0 3.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PGP_phosphatase PF09419.5 CCU98149.1 - 3.5e-42 143.6 0.0 5.5e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase P34-Arc PF04045.9 CCU98150.1 - 3.2e-101 337.6 0.0 4e-101 337.3 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Methyltransf_16 PF10294.4 CCU98151.1 - 1.3e-11 44.2 0.0 1.8e-10 40.5 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Aminotran_5 PF00266.14 CCU98152.1 - 1.3e-29 103.0 0.0 1.8e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CCU98152.1 - 0.00014 20.2 0.0 0.00026 19.3 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 CCU98152.1 - 0.0046 16.8 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain Pro_isomerase PF00160.16 CCU98153.1 - 1.4e-45 155.2 0.2 2.1e-45 154.7 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CCU98153.1 - 4.4e-07 29.4 4.7 0.0029 17.2 0.2 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CCU98153.1 - 1.7e-05 24.3 4.6 0.0048 16.7 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCU98153.1 - 0.0038 16.7 0.8 0.11 12.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCU98153.1 - 0.0067 16.3 2.4 1 9.3 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCU98153.1 - 0.13 12.0 0.3 2.9 7.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCU98153.1 - 1.1 9.8 4.9 12 6.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCU98153.1 - 1.9 9.3 5.2 5.2 7.9 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCU98153.1 - 2.9 8.6 15.5 0.47 11.1 3.3 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat RhoGAP PF00620.22 CCU98154.1 - 1.1e-38 132.1 0.2 3.3e-38 130.6 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain Mit_KHE1 PF10173.4 CCU98154.1 - 0.28 11.0 2.2 0.46 10.3 0.4 2.0 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related FCH PF00611.18 CCU98154.1 - 1.9 8.7 6.2 0.54 10.4 0.3 2.9 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Pro_isomerase PF00160.16 CCU98155.1 - 5.3e-48 163.1 0.1 6.3e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Aldedh PF00171.17 CCU98156.1 - 3.9e-162 539.7 0.0 4.4e-162 539.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCU98156.1 - 0.099 11.3 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Ribosomal_L22 PF00237.14 CCU98157.1 - 1.1e-20 73.5 0.2 1.5e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e AAA_18 PF13238.1 CCU98158.1 - 3.2e-09 37.1 0.0 5.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCU98158.1 - 0.019 15.7 0.7 0.031 15.0 0.5 1.5 1 1 0 1 1 1 0 AAA domain GDI PF00996.13 CCU98159.1 - 2.4e-201 668.7 0.0 2.7e-201 668.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CCU98159.1 - 0.019 14.9 0.0 0.069 13.1 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain peroxidase PF00141.18 CCU98161.1 - 3.1e-51 174.0 0.0 5.2e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Coatomer_E PF04733.9 CCU98162.1 - 7.8e-31 107.3 3.2 8.9e-31 107.1 2.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.12 CCU98162.1 - 0.09 12.7 3.7 2.1 8.4 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Mito_carr PF00153.22 CCU98163.1 - 3e-57 190.3 0.7 6e-20 70.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein GST_C_2 PF13410.1 CCU98163.1 - 0.00012 21.8 1.5 0.00064 19.5 0.2 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCU98163.1 - 0.00021 21.7 0.0 0.00074 19.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF2835 PF11197.3 CCU98163.1 - 0.19 11.5 0.8 0.34 10.7 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2835) Hydantoinase_A PF01968.13 CCU98165.1 - 9.4e-84 280.9 0.8 1.4e-83 280.3 0.6 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CCU98165.1 - 6.9e-52 175.4 0.2 1.4e-49 168.0 0.0 2.9 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region dCMP_cyt_deam_1 PF00383.17 CCU98166.1 - 4.5e-12 45.5 0.4 5.8e-12 45.1 0.3 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CCU98166.1 - 9.8e-09 35.2 0.5 1.2e-06 28.4 0.1 2.3 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 CCU98166.1 - 0.0034 16.7 5.5 0.028 13.8 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Carb_kinase PF01256.12 CCU98168.1 - 1.3e-48 165.4 0.0 2.2e-48 164.6 0.0 1.4 1 1 0 1 1 1 1 Carbohydrate kinase AMP-binding PF00501.23 CCU98169.1 - 1.9e-82 276.8 0.0 2.4e-82 276.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCU98169.1 - 2e-09 38.2 0.0 5.4e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 CCU98169.1 - 0.01 14.4 0.0 0.19 10.2 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter UBA_3 PF09288.5 CCU98170.1 - 1.4e-14 53.4 0.0 1.9e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain DUF1421 PF07223.6 CCU98170.1 - 0.0016 18.3 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1421) UQ_con PF00179.21 CCU98170.1 - 0.0017 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyoxalase PF00903.20 CCU98170.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PAF-AH_p_II PF03403.8 CCU98171.1 - 5e-45 153.4 0.1 2.3e-23 82.1 0.0 3.6 3 1 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 CCU98171.1 - 1.2e-11 44.5 0.0 1.4e-09 37.8 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCU98171.1 - 8.7e-07 29.0 0.0 9.9e-06 25.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 CCU98171.1 - 1.1e-05 24.4 0.0 0.00034 19.6 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 CCU98171.1 - 3.9e-05 22.5 0.0 0.00042 19.2 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 CCU98171.1 - 0.0022 17.7 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CCU98171.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCU98171.1 - 0.03 13.5 0.0 0.46 9.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family IGR PF09597.5 CCU98172.1 - 4.3e-11 42.5 0.0 6.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif V-SNARE PF05008.10 CCU98173.1 - 1.7e-17 63.3 1.3 1.7e-17 63.3 0.9 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 CCU98173.1 - 5.1e-14 52.0 3.1 1.3e-13 50.7 2.2 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus CENP-F_leu_zip PF10473.4 CCU98173.1 - 0.024 14.4 0.6 0.056 13.3 0.1 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tup_N PF08581.5 CCU98173.1 - 0.13 12.5 1.8 1.1 9.4 0.1 2.7 3 1 0 3 3 3 0 Tup N-terminal DUF883 PF05957.8 CCU98173.1 - 0.21 11.9 8.5 3.9 7.9 2.0 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Mnd1 PF03962.10 CCU98173.1 - 0.34 10.5 1.7 0.59 9.7 0.2 1.9 1 1 1 2 2 2 0 Mnd1 family Syntaxin_2 PF14523.1 CCU98173.1 - 3.3 7.7 5.2 10 6.2 0.5 3.1 2 2 0 2 2 2 0 Syntaxin-like protein BCDHK_Adom3 PF10436.4 CCU98174.1 - 2.4e-42 144.2 0.0 3.1e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCU98174.1 - 6e-14 51.6 0.0 5.8e-13 48.5 0.0 2.4 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CCU98174.1 - 0.00093 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SHR3_chaperone PF08229.6 CCU98175.1 - 3.9e-22 78.1 0.1 6.2e-22 77.5 0.1 1.3 1 1 0 1 1 1 1 ER membrane protein SH3 SecG PF03840.9 CCU98175.1 - 0.055 13.2 0.4 0.055 13.2 0.3 2.6 4 0 0 4 4 4 0 Preprotein translocase SecG subunit DUF4084 PF13321.1 CCU98175.1 - 0.056 12.6 0.3 0.083 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4084) ABC_tran PF00005.22 CCU98177.1 - 2.7e-35 121.6 0.0 5.3e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CCU98177.1 - 3.5e-29 102.0 10.0 5.9e-29 101.3 6.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CCU98177.1 - 1.9e-05 24.7 0.0 0.011 15.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 CCU98177.1 - 2.5e-05 23.6 0.0 0.00042 19.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CCU98177.1 - 0.00055 19.9 0.1 0.00055 19.9 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CCU98177.1 - 0.001 18.5 0.1 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCU98177.1 - 0.013 15.6 0.2 0.061 13.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain ABC_membrane_3 PF13748.1 CCU98177.1 - 0.016 14.2 0.2 0.016 14.2 0.1 2.4 4 0 0 4 4 4 0 ABC transporter transmembrane region AAA PF00004.24 CCU98177.1 - 0.032 14.4 0.0 0.33 11.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCU98177.1 - 0.04 14.7 0.0 0.089 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CCU98177.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 CCU98177.1 - 0.054 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF2611 PF11022.3 CCU98177.1 - 0.073 13.1 0.3 4.1 7.5 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) DUF258 PF03193.11 CCU98177.1 - 0.079 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCU98177.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PLAC8 PF04749.12 CCU98177.1 - 0.28 11.7 0.6 0.67 10.5 0.1 1.9 2 0 0 2 2 1 0 PLAC8 family G-alpha PF00503.15 CCU98177.1 - 0.45 9.1 3.2 0.17 10.5 0.0 1.9 1 1 1 2 2 2 0 G-protein alpha subunit DUF2413 PF10310.4 CCU98177.1 - 5.6 5.6 17.1 9.1 4.9 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) HpcH_HpaI PF03328.9 CCU98178.1 - 5.4e-32 110.4 1.7 6.8e-32 110.1 1.2 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 CCU98178.1 - 3.1e-13 49.2 0.5 1.3e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold FAR1 PF03101.10 CCU98179.1 - 0.002 18.6 0.1 0.005 17.3 0.1 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain Pribosyltran PF00156.22 CCU98180.1 - 2.3e-16 59.6 0.0 3.1e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCU98180.1 - 0.0021 17.3 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 CCU98180.1 - 0.1 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 PRTase ComF-like CGI-121 PF08617.5 CCU98181.1 - 5.2e-31 107.4 0.0 7e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Kinase binding protein CGI-121 GLTSCR1 PF15249.1 CCU98182.1 - 2.4e-13 50.1 4.7 8.8e-13 48.3 3.2 1.9 1 1 0 1 1 1 1 Glioma tumor suppressor candidate region Ribosomal_L1 PF00687.16 CCU98183.1 - 1.6e-20 73.3 0.0 5.6e-20 71.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family DUF3635 PF12330.3 CCU98184.1 - 2e-14 53.4 0.0 4e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Pkinase PF00069.20 CCU98184.1 - 0.003 16.7 0.0 0.0063 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98184.1 - 0.17 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Sugar_tr PF00083.19 CCU98186.1 - 3.7e-207 688.3 49.2 3.8e-105 352.0 17.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCU98186.1 - 4.1e-45 154.0 86.7 1.8e-22 79.5 21.6 4.1 2 2 2 4 4 4 3 Major Facilitator Superfamily FAE1_CUT1_RppA PF08392.7 CCU98186.1 - 0.24 10.4 0.0 10 5.0 0.0 2.2 2 0 0 2 2 2 0 FAE1/Type III polyketide synthase-like protein GARS_A PF01071.14 CCU98187.1 - 8.9e-72 240.7 0.0 1.3e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 CCU98187.1 - 8.6e-34 116.0 0.0 1.8e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 CCU98187.1 - 2.2e-29 102.4 0.0 4.6e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 CCU98187.1 - 3.5e-28 97.6 0.7 3.7e-27 94.3 0.1 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 CCU98187.1 - 3.5e-17 62.4 4.3 3.9e-17 62.2 0.4 2.8 3 1 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.1 CCU98187.1 - 6.1e-08 31.7 0.0 1.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CCU98187.1 - 3.1e-06 27.0 0.0 1.1e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CCU98187.1 - 0.00094 19.0 0.0 0.0023 17.8 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.5 CCU98187.1 - 0.041 13.2 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain WD40 PF00400.27 CCU98188.1 - 1.5e-25 88.1 15.0 3.8e-10 39.2 0.4 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCU98188.1 - 8.5e-20 70.4 0.1 2.6e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 CCU98188.1 - 8.2e-05 22.3 0.0 0.0005 19.8 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Es2 PF09751.4 CCU98190.1 - 1.5e-51 176.1 1.1 2.5e-51 175.4 0.7 1.3 1 0 0 1 1 1 1 Nuclear protein Es2 Rsm22 PF09243.5 CCU98191.1 - 6.2e-36 123.8 0.2 7.9e-25 87.4 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Ima1_N PF09779.4 CCU98192.1 - 4e-09 37.0 0.1 4e-09 37.0 0.1 1.6 2 0 0 2 2 2 1 Ima1 N-terminal domain Lyase_1 PF00206.15 CCU98193.1 - 1.8e-120 401.8 0.1 2.5e-120 401.3 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CCU98193.1 - 4.4e-19 68.2 0.1 9.3e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus RRM_1 PF00076.17 CCU98194.1 - 1.4e-18 66.2 0.0 7.9e-10 38.2 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU98194.1 - 4.8e-12 45.5 0.0 1e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU98194.1 - 5.3e-12 45.5 0.3 0.00016 21.6 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 CCU98194.1 - 0.0046 16.5 0.0 0.0097 15.5 0.0 1.5 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 CCU98194.1 - 0.07 12.8 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 Ilar_coat PF01787.11 CCU98194.1 - 0.21 11.1 3.2 0.34 10.4 2.2 1.3 1 0 0 1 1 1 0 Ilarvirus coat protein Pescadillo_N PF06732.6 CCU98195.1 - 2.6e-116 387.8 0.3 2.6e-116 387.8 0.2 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 CCU98195.1 - 0.00063 19.8 0.0 0.0016 18.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BUD22 PF09073.5 CCU98196.1 - 4.5e-50 170.9 15.3 1.6e-48 165.8 10.6 2.0 1 1 0 1 1 1 1 BUD22 Ribosomal_60s PF00428.14 CCU98196.1 - 0.03 14.7 1.4 0.03 14.7 1.0 4.1 2 1 0 2 2 2 0 60s Acidic ribosomal protein Pyr_redox_3 PF13738.1 CCU98197.1 - 2.9e-19 69.9 0.0 3.3e-18 66.5 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCU98197.1 - 1.6e-08 33.2 0.0 3.7e-08 32.0 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 CCU98197.1 - 3.2e-06 27.1 0.0 4.3e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCU98197.1 - 3.2e-06 26.2 0.0 0.0015 17.5 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CCU98197.1 - 1.5e-05 24.9 0.0 3.6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCU98197.1 - 4e-05 22.6 0.1 0.08 11.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCU98197.1 - 0.0071 16.1 0.1 4.3 7.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 CCU98197.1 - 0.0086 15.0 0.1 2.7 6.8 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.22 CCU98197.1 - 0.08 13.3 0.0 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4060 PF13269.1 CCU98197.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4060) NAD_binding_7 PF13241.1 CCU98197.1 - 0.11 12.7 0.0 0.64 10.2 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Thioredoxin PF00085.15 CCU98198.1 - 2.1e-31 107.6 0.1 2.4e-31 107.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CCU98198.1 - 2.7e-10 40.4 0.1 2.5e-09 37.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCU98198.1 - 1.2e-07 31.7 0.0 0.00015 21.8 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 CCU98198.1 - 1.1e-05 24.9 0.0 1.2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CCU98198.1 - 3.6e-05 23.4 0.3 0.00041 20.0 0.1 1.9 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CCU98198.1 - 0.00015 21.3 0.7 0.0041 16.6 0.1 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 CCU98198.1 - 0.00058 19.8 0.0 0.00086 19.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.11 CCU98198.1 - 0.02 14.4 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 HyaE PF07449.6 CCU98198.1 - 0.032 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.1 CCU98198.1 - 0.033 13.7 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.15 CCU98198.1 - 0.046 13.2 0.6 0.07 12.6 0.1 1.5 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Glutaredoxin PF00462.19 CCU98198.1 - 0.075 13.0 0.3 0.19 11.7 0.2 1.7 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_4 PF13462.1 CCU98198.1 - 0.095 12.7 0.3 0.36 10.8 0.1 1.8 1 1 1 2 2 2 0 Thioredoxin MTP18 PF10558.4 CCU98199.1 - 1.5e-48 164.4 0.1 2.2e-48 163.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Exo_endo_phos PF03372.18 CCU98200.1 - 4.4e-12 46.4 0.0 7.5e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ubie_methyltran PF01209.13 CCU98201.1 - 1.2e-70 237.2 0.0 8.7e-37 126.4 0.0 2.4 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CCU98201.1 - 9.4e-10 38.8 0.0 2.5e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 CCU98201.1 - 2.3e-09 37.5 0.0 5.8e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCU98201.1 - 6.1e-09 35.6 0.0 0.00042 19.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 CCU98201.1 - 3e-07 30.9 0.0 6.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCU98201.1 - 4.8e-07 30.0 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCU98201.1 - 3e-06 27.0 0.0 5.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCU98201.1 - 0.00015 21.7 0.0 0.0014 18.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Suc_Fer-like PF06999.7 CCU98202.1 - 4.3e-24 85.8 0.2 3.1e-23 83.0 0.1 2.0 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Fer2 PF00111.22 CCU98202.1 - 7.7e-08 31.9 1.5 7.7e-08 31.9 1.0 2.5 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain SSB PF00436.20 CCU98203.1 - 1.1e-13 50.9 0.0 1.3e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Band_7 PF01145.20 CCU98205.1 - 3.7e-26 92.1 2.1 6e-26 91.4 1.5 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Acetyltransf_3 PF13302.1 CCU98206.1 - 5.4e-17 62.2 0.0 6.5e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCU98206.1 - 6.2e-07 29.0 0.0 2e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 CCU98206.1 - 3e-06 27.2 0.0 6.7e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCU98206.1 - 0.00012 22.0 0.0 0.00024 21.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 CCU98206.1 - 0.0095 15.8 0.0 0.028 14.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.10 CCU98207.1 - 1.7e-08 34.1 0.0 3.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCU98207.1 - 1.8e-07 31.2 0.0 3.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CCU98207.1 - 0.0035 17.8 0.0 0.005 17.2 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like SWIB PF02201.13 CCU98208.1 - 2.9e-22 78.1 0.1 5.1e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 CCU98208.1 - 2.3e-07 30.4 0.5 1.6e-06 27.7 0.3 2.2 1 1 0 1 1 1 1 DEK C terminal domain Vfa1 PF08432.5 CCU98208.1 - 0.055 13.5 6.8 0.072 13.1 4.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.3 CCU98208.1 - 0.14 10.8 3.3 0.17 10.6 2.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PRTP PF01366.13 CCU98208.1 - 0.21 9.5 1.9 0.59 8.0 1.0 1.8 1 1 1 2 2 2 0 Herpesvirus processing and transport protein Sec62 PF03839.11 CCU98208.1 - 6.1 6.1 8.9 4.6 6.5 5.4 1.4 1 1 0 1 1 1 0 Translocation protein Sec62 CBFD_NFYB_HMF PF00808.18 CCU98209.1 - 1.6e-08 34.4 1.5 1.2e-07 31.7 1.1 2.0 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCU98209.1 - 0.0097 16.0 0.2 0.033 14.3 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Translin PF01997.11 CCU98210.1 - 1.3e-38 132.6 0.0 1.5e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Translin family DUF1320 PF07030.7 CCU98210.1 - 0.053 13.2 3.6 0.39 10.4 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1320) Abhydrolase_6 PF12697.2 CCU98211.1 - 2.7e-32 112.4 7.6 2.7e-32 112.4 5.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCU98211.1 - 3e-18 66.2 0.0 6.2e-18 65.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCU98211.1 - 3e-14 53.0 0.1 3.6e-13 49.5 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CCU98211.1 - 6.3e-06 25.7 0.0 9.4e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 CCU98211.1 - 1.7e-05 24.4 0.0 0.00013 21.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 CCU98211.1 - 0.00012 21.7 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Ndr PF03096.9 CCU98211.1 - 0.00077 18.0 0.0 0.0012 17.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.11 CCU98211.1 - 0.0015 18.0 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase UPF0227 PF05728.7 CCU98211.1 - 0.0018 17.9 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 CCU98211.1 - 0.0019 17.8 0.5 0.088 12.3 0.3 2.3 1 1 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 CCU98211.1 - 0.0092 15.0 0.0 0.17 10.9 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.16 CCU98211.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2305 PF10230.4 CCU98211.1 - 0.026 13.9 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 CCU98211.1 - 0.027 14.0 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.6 CCU98211.1 - 0.081 11.7 0.0 0.21 10.3 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase Thioesterase PF00975.15 CCU98211.1 - 0.12 12.5 1.4 0.41 10.8 1.0 2.0 1 1 0 1 1 1 0 Thioesterase domain NPL4 PF05021.10 CCU98212.1 - 3.5e-99 331.8 0.0 4.4e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 CCU98212.1 - 3.1e-65 218.3 0.0 4.5e-65 217.7 0.0 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 CCU98212.1 - 0.025 14.8 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DZR PF12773.2 CCU98212.1 - 0.038 13.7 0.5 0.038 13.7 0.4 2.9 3 1 0 3 3 3 0 Double zinc ribbon zf-RanBP PF00641.13 CCU98212.1 - 6.5 5.9 7.2 0.16 11.1 0.4 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PHA_synth_III_E PF09712.5 CCU98213.1 - 0.004 16.6 1.2 0.0047 16.3 0.1 1.6 2 0 0 2 2 2 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) IncA PF04156.9 CCU98214.1 - 0.00023 20.8 2.5 0.00051 19.6 1.7 1.5 1 0 0 1 1 1 1 IncA protein Rootletin PF15035.1 CCU98214.1 - 0.0013 18.6 5.7 0.0013 18.6 4.0 1.8 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion RasGAP_C PF03836.10 CCU98214.1 - 0.0015 18.2 0.5 0.0028 17.3 0.4 1.3 1 0 0 1 1 1 1 RasGAP C-terminus DUF2353 PF09789.4 CCU98214.1 - 0.0084 15.4 1.9 0.014 14.6 1.3 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Spc7 PF08317.6 CCU98214.1 - 0.034 12.8 2.0 0.054 12.1 1.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 CCU98214.1 - 0.035 13.6 1.6 0.059 12.9 1.1 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 CCU98214.1 - 0.048 13.5 9.0 0.023 14.5 4.3 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 CCU98214.1 - 0.068 10.5 12.5 0.098 9.9 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-H PF05837.7 CCU98214.1 - 0.11 12.7 3.3 0.24 11.6 1.9 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.3 CCU98214.1 - 0.26 11.1 6.1 0.58 9.9 3.8 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 CCU98214.1 - 0.5 8.7 0.9 0.72 8.2 0.6 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 CCU98214.1 - 0.97 8.4 5.6 1.7 7.6 3.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 CCU98214.1 - 1.5 8.4 7.8 3.6 7.1 5.4 1.6 1 0 0 1 1 1 0 Mnd1 family OmpH PF03938.9 CCU98214.1 - 2.7 7.9 12.3 1.6 8.6 6.5 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ras PF00071.17 CCU98215.1 - 1.4e-41 141.5 0.0 1.7e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU98215.1 - 4.8e-09 36.7 0.0 6.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCU98215.1 - 0.00089 18.5 0.0 0.0013 18.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ribosomal_L29 PF00831.18 CCU98216.1 - 0.00018 21.0 5.6 0.00032 20.3 0.2 2.3 2 0 0 2 2 2 2 Ribosomal L29 protein DUF1713 PF08213.6 CCU98216.1 - 0.51 10.0 5.8 2 8.1 4.0 2.0 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) SecE PF00584.15 CCU98217.1 - 1.6e-14 53.1 0.0 1.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Img2 PF05046.9 CCU98218.1 - 2.5e-14 53.2 0.0 8.7e-14 51.5 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) COX5B PF01215.14 CCU98219.1 - 3.3e-30 104.5 0.0 3.8e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb GFA PF04828.9 CCU98219.1 - 0.052 13.4 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme SH3_1 PF00018.23 CCU98220.1 - 1.4e-11 43.5 0.1 2.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCU98220.1 - 1.8e-10 40.1 0.0 3.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCU98220.1 - 3.8e-10 39.0 0.0 7.1e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4342 PF14242.1 CCU98220.1 - 0.028 14.1 0.1 0.061 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) NTR2 PF15458.1 CCU98221.1 - 2.5e-23 82.6 20.4 8.1e-15 54.7 4.0 2.2 2 0 0 2 2 2 2 Nineteen complex-related protein 2 Macoilin PF09726.4 CCU98221.1 - 0.032 12.5 1.1 0.044 12.0 0.7 1.1 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 CCU98221.1 - 0.037 13.6 0.4 0.098 12.2 0.3 1.8 1 0 0 1 1 1 0 IncA protein L27_1 PF09058.5 CCU98221.1 - 0.63 9.9 3.8 18 5.3 0.0 3.0 3 0 0 3 3 3 0 L27_1 DUF1253 PF06862.7 CCU98222.1 - 1.9e-147 491.2 0.0 2.2e-147 491.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) MMR_HSR1 PF01926.18 CCU98223.1 - 4.2e-16 58.9 0.0 5.5e-15 55.3 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCU98223.1 - 7.4e-05 22.0 0.0 0.00027 20.2 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CCU98223.1 - 7.7e-05 21.9 0.0 0.00016 20.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CCU98223.1 - 0.0092 15.8 0.3 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 CCU98223.1 - 0.01 14.9 0.0 0.024 13.7 0.0 1.6 1 0 0 1 1 1 1 AIG1 family MEDS PF14417.1 CCU98223.1 - 0.037 13.1 0.1 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Miro PF08477.8 CCU98223.1 - 0.047 14.1 0.1 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Peptidase_S9_N PF02897.10 CCU98224.1 - 4.1e-84 282.5 0.4 5.8e-84 282.0 0.3 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CCU98224.1 - 2.5e-46 157.5 1.1 4.7e-46 156.6 0.8 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Herpes_TAF50 PF03326.8 CCU98224.1 - 0.11 11.4 0.6 0.17 10.7 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) PUA PF01472.15 CCU98225.1 - 2.8e-15 55.7 0.0 3.9e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 PUA domain Peptidase_C12 PF01088.16 CCU98227.1 - 2.1e-60 203.5 0.0 2.4e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UDG PF03167.14 CCU98228.1 - 1.5e-12 47.2 0.0 2.3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Pro_CA PF00484.14 CCU98229.1 - 1.2e-41 142.2 0.1 1.6e-41 141.8 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase NAD_binding_10 PF13460.1 CCU98229.1 - 0.071 13.1 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding ADH_zinc_N PF00107.21 CCU98230.1 - 3.3e-19 68.7 0.1 5.1e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCU98230.1 - 5.2e-15 55.1 7.9 1.9e-14 53.3 3.6 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 CCU98230.1 - 0.00068 18.8 0.4 0.0034 16.5 0.2 2.0 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 CCU98230.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 CCU98230.1 - 0.022 14.3 0.3 0.083 12.4 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 CCU98230.1 - 0.054 13.4 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Oxidored_nitro PF00148.14 CCU98230.1 - 0.069 11.7 0.0 0.085 11.4 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Polyketide_cyc PF03364.15 CCU98231.1 - 8.3e-24 84.0 0.0 1.1e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 CCU98231.1 - 0.0092 16.1 0.0 0.013 15.7 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Prenyltransf PF01255.14 CCU98232.1 - 4.6e-59 199.2 0.0 1.1e-58 198.0 0.0 1.6 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase MIP-T3 PF10243.4 CCU98232.1 - 0.00093 17.7 36.6 0.0013 17.3 25.4 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 CCU98232.1 - 0.0018 17.7 46.9 0.0027 17.0 32.5 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CCU98232.1 - 0.081 12.2 17.6 0.13 11.6 12.2 1.3 1 0 0 1 1 1 0 SprA-related family SOBP PF15279.1 CCU98232.1 - 0.1 13.0 7.2 0.15 12.4 5.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.9 CCU98232.1 - 0.12 10.3 23.3 0.19 9.7 16.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.4 CCU98232.1 - 0.36 9.6 18.0 0.5 9.1 12.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain LMBR1 PF04791.11 CCU98232.1 - 2.5 6.6 6.6 2.8 6.4 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.6 CCU98232.1 - 3 5.9 26.1 4.2 5.5 18.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.7 CCU98232.1 - 6.5 6.5 21.5 14 5.4 14.9 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3844 PF12955.2 CCU98233.1 - 4.3e-23 81.3 0.2 6.8e-23 80.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) His_Phos_2 PF00328.17 CCU98233.1 - 2e-19 70.1 0.0 4.1e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Mito_carr PF00153.22 CCU98234.1 - 3.6e-28 97.1 0.7 1.9e-14 53.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Iso_dh PF00180.15 CCU98235.1 - 5.9e-65 219.4 0.0 7.3e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_88 PF07470.8 CCU98236.1 - 1.7e-17 63.4 0.0 3.3e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Init_tRNA_PT PF04179.7 CCU98237.1 - 3.1e-84 283.4 0.0 3.9e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Pro-kuma_activ PF09286.6 CCU98238.1 - 1.8e-26 92.8 0.0 3.3e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCU98238.1 - 3.1e-11 42.9 0.0 4.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Rotamase PF00639.16 CCU98239.1 - 1.7e-21 76.7 0.0 3.4e-20 72.5 0.0 2.1 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CCU98239.1 - 2e-16 60.2 0.0 6.3e-16 58.6 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CCU98239.1 - 9.5e-07 29.4 0.0 1.3e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 CCU98239.1 - 2.2e-05 24.1 0.3 4.5e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 WW domain PLRV_ORF5 PF01690.12 CCU98240.1 - 2.8 6.9 6.2 4.8 6.2 4.3 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CMAS PF02353.15 CCU98241.1 - 1.1e-64 218.1 0.0 1.4e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CCU98241.1 - 1.7e-14 53.8 0.0 2.9e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCU98241.1 - 4.1e-11 43.2 0.0 1.8e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCU98241.1 - 1.2e-08 35.0 0.0 3.6e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCU98241.1 - 6.5e-08 32.3 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCU98241.1 - 6.9e-08 32.7 0.0 1.7e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCU98241.1 - 4.4e-07 30.4 0.0 8.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCU98241.1 - 9.3e-07 29.2 0.0 2.4e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCU98241.1 - 2.3e-05 23.8 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 CCU98241.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 CCU98241.1 - 0.0022 17.3 0.0 0.022 14.0 0.0 2.1 2 0 0 2 2 2 1 Histone methylation protein DOT1 Met_10 PF02475.11 CCU98241.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.8 CCU98241.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 CCU98241.1 - 0.033 13.5 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Gtr1_RagA PF04670.7 CCU98242.1 - 9.8e-82 273.5 0.0 1.3e-81 273.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CCU98242.1 - 9.4e-05 21.7 0.0 0.00028 20.1 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 CCU98242.1 - 0.00087 18.7 0.0 0.0015 17.9 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CCU98242.1 - 0.0057 17.1 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCU98242.1 - 0.0082 16.0 0.0 0.04 13.8 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF1640 PF07798.6 CCU98243.1 - 3.8e-65 219.2 4.1 4.3e-65 219.0 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) LppC PF04348.8 CCU98243.1 - 0.0094 14.5 1.5 0.0096 14.5 1.1 1.1 1 0 0 1 1 1 1 LppC putative lipoprotein HALZ PF02183.13 CCU98243.1 - 0.054 13.2 2.3 0.45 10.2 1.6 2.4 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF732 PF05305.9 CCU98243.1 - 0.069 13.2 0.1 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF732) FlaC_arch PF05377.6 CCU98243.1 - 0.41 10.5 3.5 3.9 7.4 0.5 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Pyridox_oxidase PF01243.15 CCU98244.1 - 2.6e-17 62.5 0.2 1.2e-16 60.4 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 CCU98244.1 - 6.1e-14 51.2 3.3 1.2e-13 50.2 2.3 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 CCU98244.1 - 0.01 16.1 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase HlyIII PF03006.15 CCU98245.1 - 6.7e-23 81.2 8.4 9.2e-23 80.8 5.8 1.2 1 0 0 1 1 1 1 Haemolysin-III related UPF0060 PF02694.10 CCU98245.1 - 0.0093 15.9 3.2 0.042 13.8 0.4 2.3 1 1 1 2 2 2 2 Uncharacterised BCR, YnfA/UPF0060 family Rep_fac_C PF08542.6 CCU98246.1 - 6.1e-16 58.1 0.0 2.6e-15 56.1 0.0 2.0 1 1 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CCU98246.1 - 5.2e-10 39.2 0.0 7.6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CCU98246.1 - 0.00023 21.3 0.0 0.00044 20.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PPR_1 PF12854.2 CCU98246.1 - 0.081 12.4 0.2 0.2 11.1 0.1 1.7 1 0 0 1 1 1 0 PPR repeat Kelch_5 PF13854.1 CCU98247.1 - 8.9e-37 124.4 6.6 1.4e-06 28.0 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 CCU98247.1 - 6e-36 121.8 8.8 1.2e-07 31.7 0.1 7.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CCU98247.1 - 1.6e-33 114.2 15.0 1.7e-06 27.7 0.3 6.7 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 CCU98247.1 - 9.6e-27 92.0 6.0 3.7e-09 36.3 0.4 6.5 4 1 2 6 6 6 6 Kelch motif Kelch_1 PF01344.20 CCU98247.1 - 2.9e-23 81.1 4.7 7.4e-07 28.6 0.4 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CCU98247.1 - 5.9e-22 76.5 7.6 0.00047 19.8 0.3 6.5 6 0 0 6 6 6 5 Kelch motif NAD_synthase PF02540.12 CCU98249.1 - 1.9e-25 89.1 0.0 1.9e-24 85.8 0.0 2.0 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 CCU98249.1 - 2.7e-18 65.9 0.0 4.8e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Methyltransf_18 PF12847.2 CCU98249.1 - 5.4e-06 26.9 0.1 3.5e-05 24.3 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCU98249.1 - 0.00056 19.6 0.0 0.002 17.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCU98249.1 - 0.00084 18.9 0.0 0.0021 17.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCU98249.1 - 0.0049 17.2 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCU98249.1 - 0.0065 16.9 0.3 0.038 14.4 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Rhodanese PF00581.15 CCU98249.1 - 0.0078 16.5 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_12 PF08242.7 CCU98249.1 - 0.029 14.8 0.0 0.078 13.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Asn_synthase PF00733.16 CCU98249.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase Methyltransf_26 PF13659.1 CCU98249.1 - 0.82 9.7 11.2 1.1 9.3 3.7 3.6 2 2 0 2 2 2 0 Methyltransferase domain adh_short PF00106.20 CCU98250.1 - 1.5e-25 90.0 0.1 2.1e-25 89.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCU98250.1 - 4.6e-09 36.1 0.1 7.2e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCU98250.1 - 4.1e-06 26.7 0.0 5.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCU98250.1 - 3.6e-05 23.8 0.1 7.5e-05 22.8 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CCU98250.1 - 0.0066 15.3 0.0 0.0085 15.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.8 CCU98250.1 - 0.042 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family SPOC PF07744.8 CCU98251.1 - 0.018 15.5 0.1 0.18 12.3 0.0 2.4 2 0 0 2 2 2 0 SPOC domain Usp PF00582.21 CCU98252.1 - 1.3e-15 57.8 0.1 1.7e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Glyco_transf_20 PF00982.16 CCU98253.1 - 2.1e-178 593.6 0.0 1.1e-133 446.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Arginosuc_synth PF00764.14 CCU98254.1 - 2.1e-150 501.1 0.0 2.4e-150 500.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Ish1 PF10281.4 CCU98254.1 - 0.17 11.9 0.1 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein TTL PF03133.10 CCU98256.1 - 1.5e-18 66.7 0.1 1.9e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 CCU98256.1 - 0.003 17.3 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Herpes_pp85 PF04637.7 CCU98256.1 - 0.066 11.5 0.0 0.093 11.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) zf-C2H2 PF00096.21 CCU98257.1 - 9.1e-29 98.0 83.1 0.00012 22.2 3.5 10.3 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCU98257.1 - 6.4e-27 91.8 74.0 0.0042 17.3 2.3 10.4 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCU98257.1 - 3.7e-15 55.3 70.6 1.8e-05 24.8 0.2 11.1 11 2 0 11 11 11 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCU98257.1 - 0.00019 21.4 35.6 0.028 14.5 0.4 9.0 9 1 0 9 9 9 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCU98257.1 - 1.9 8.7 34.7 12 6.2 0.1 9.2 9 1 0 9 9 9 0 Zinc-finger of C2H2 type RRM_1 PF00076.17 CCU98258.1 - 1.1e-31 108.2 0.5 1.2e-18 66.5 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU98258.1 - 2.6e-25 88.1 0.2 1.3e-15 57.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU98258.1 - 3.3e-21 74.8 0.4 6.1e-11 42.0 0.1 3.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 CCU98258.1 - 1.4e-08 34.9 0.4 6.4e-08 32.7 0.2 2.1 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 CCU98258.1 - 6.4e-05 22.7 0.1 0.077 12.8 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 CCU98258.1 - 0.00068 19.3 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.1 CCU98258.1 - 0.018 14.4 0.0 0.83 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) Glycos_transf_1 PF00534.15 CCU98260.1 - 2.8e-33 114.7 0.0 1.8e-32 112.1 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CCU98260.1 - 2.2e-11 44.0 0.0 1.2e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCU98260.1 - 1.3e-09 38.3 0.0 3.7e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 CCU98260.1 - 1.5e-09 37.8 0.0 2.7e-08 33.7 0.0 2.2 1 1 1 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 CCU98260.1 - 0.0033 17.6 0.6 0.68 10.2 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 BING4CT PF08149.6 CCU98261.1 - 3.2e-36 122.6 0.0 2.9e-35 119.6 0.0 2.6 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 CCU98261.1 - 1.1e-06 28.3 0.0 0.0002 21.1 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CCU98261.1 - 1.5e-05 24.0 0.0 2.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Spt5_N PF11942.3 CCU98261.1 - 8.1 7.1 9.3 1.2 9.8 2.3 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PRK PF00485.13 CCU98262.1 - 2.9e-48 163.9 0.0 4.1e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 CCU98262.1 - 1.5e-41 141.9 0.0 9.5e-39 132.7 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.1 CCU98262.1 - 3.7e-06 27.2 0.0 1.5e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 CCU98262.1 - 0.0004 20.0 0.0 0.0011 18.6 0.0 1.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 CCU98262.1 - 0.0015 19.2 0.0 0.0033 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCU98262.1 - 0.0093 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 CCU98262.1 - 0.74 9.1 2.2 2.8 7.2 1.5 1.9 1 1 0 1 1 1 0 Dephospho-CoA kinase Molybdopterin PF00384.17 CCU98263.1 - 2.4e-68 230.8 0.0 3.2e-66 223.8 0.0 2.8 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 CCU98263.1 - 2e-17 62.0 0.1 5.8e-17 60.6 0.0 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 CCU98263.1 - 1.7e-16 59.7 0.0 4.7e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 CCU98263.1 - 6.8e-16 58.1 0.1 1.7e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 CCU98263.1 - 3.8e-08 32.9 2.1 3.9e-08 32.9 0.3 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 CCU98263.1 - 0.00046 19.9 0.1 0.039 13.7 0.0 2.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Ank_5 PF13857.1 CCU98263.1 - 0.083 13.1 0.0 8 6.8 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Fer4 PF00037.22 CCU98263.1 - 0.17 11.5 1.7 6.8 6.4 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Arf PF00025.16 CCU98264.1 - 6.1e-13 48.3 0.0 8.6e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MgtE_N PF03448.12 CCU98264.1 - 0.047 14.0 0.0 0.069 13.4 0.0 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain Miro PF08477.8 CCU98264.1 - 0.053 14.0 0.0 0.15 12.6 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein RRS1 PF04939.7 CCU98266.1 - 2.2e-57 193.1 4.4 3e-57 192.6 3.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Ribul_P_3_epim PF00834.14 CCU98268.1 - 4.1e-58 195.8 0.1 5.7e-58 195.3 0.1 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.5 CCU98268.1 - 0.00076 19.4 0.1 0.0028 17.6 0.0 1.9 2 0 0 2 2 2 1 Predicted Peptidoglycan domain QRPTase_C PF01729.14 CCU98268.1 - 0.033 13.7 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.12 CCU98268.1 - 0.08 12.1 0.1 0.21 10.8 0.0 1.6 1 1 0 1 1 1 0 PcrB family Peptidase_A22B PF04258.8 CCU98269.1 - 7.2e-74 248.9 6.2 8.9e-74 248.6 4.3 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 CCU98269.1 - 7.7e-05 21.9 7.3 0.0002 20.5 5.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) MIF4G PF02854.14 CCU98270.1 - 2.2e-19 69.7 0.0 1.5e-16 60.4 0.0 2.6 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.12 CCU98270.1 - 6.7e-14 51.5 0.0 3.1e-13 49.4 0.0 2.3 3 0 0 3 3 3 1 MA3 domain DUF2510 PF10708.4 CCU98270.1 - 0.13 11.7 3.4 0.31 10.5 2.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) Tim54 PF11711.3 CCU98270.1 - 1.4 7.3 3.8 2.3 6.7 2.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Tom37_C PF11801.3 CCU98270.1 - 6.6 6.5 5.8 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain DEAD PF00270.24 CCU98271.1 - 2.7e-41 140.8 0.0 1.6e-40 138.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU98271.1 - 5e-26 90.3 0.2 9.7e-26 89.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCU98271.1 - 4.8e-06 25.5 0.0 6.9e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CCU98271.1 - 4.5e-05 23.3 0.0 0.0001 22.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCU98271.1 - 0.00025 20.7 0.3 0.00099 18.8 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain DUF1253 PF06862.7 CCU98271.1 - 0.0017 16.8 0.0 0.24 9.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_22 PF13401.1 CCU98271.1 - 0.0019 18.3 0.1 0.0071 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CCU98271.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.9 CCU98271.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.6 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_C_2 PF13307.1 CCU98271.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain Herpes_ori_bp PF02399.10 CCU98271.1 - 0.22 9.4 0.0 0.3 8.9 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein Spc7 PF08317.6 CCU98272.1 - 8e-33 113.4 0.1 1.2e-32 112.9 0.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 CCU98272.1 - 0.022 14.4 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Spc7_C2 Atg14 PF10186.4 CCU98272.1 - 1.5 7.7 8.8 31 3.3 0.0 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Enkurin PF13864.1 CCU98272.1 - 1.7 8.8 6.6 2.1 8.6 3.5 1.9 1 1 0 1 1 1 0 Calmodulin-binding Dus PF01207.12 CCU98274.1 - 1.5e-37 129.1 0.3 2.3e-37 128.5 0.2 1.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TEX13 PF15186.1 CCU98274.1 - 0.0055 16.2 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 Testis-expressed sequence 13 protein family DUF849 PF05853.7 CCU98274.1 - 0.077 11.8 0.7 0.13 11.1 0.5 1.4 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) ubiquitin PF00240.18 CCU98275.1 - 1.9e-05 23.9 0.0 5e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family DUF4010 PF13194.1 CCU98275.1 - 0.00026 20.3 2.2 0.00043 19.6 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4010) Rad60-SLD_2 PF13881.1 CCU98275.1 - 0.0012 18.7 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCU98275.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain VPS28 PF03997.7 CCU98276.1 - 4.5e-37 127.4 0.0 5.4e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 CCU98276.1 - 0.037 13.8 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Gas vesicle protein G RRM_1 PF00076.17 CCU98277.1 - 8.2e-17 60.6 0.0 1.4e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU98277.1 - 3.8e-14 52.4 0.0 7e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU98277.1 - 1.7e-07 30.9 0.0 3.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTP_transf_1 PF01148.15 CCU98277.1 - 3e-07 30.3 9.4 3e-07 30.3 6.5 4.1 3 2 1 4 4 4 1 Cytidylyltransferase family U1snRNP70_N PF12220.3 CCU98277.1 - 3.1e-07 30.5 13.6 1.2e-06 28.6 7.8 2.6 2 1 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Proteasome PF00227.21 CCU98278.1 - 5.1e-48 162.8 0.0 6.4e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCU98278.1 - 1.1e-12 47.0 0.2 2.4e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MSC PF09402.5 CCU98279.1 - 2e-56 191.1 0.0 2.4e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 CCU98279.1 - 7.9e-10 38.1 0.1 1.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.22 CCU98279.1 - 0.015 14.8 0.0 0.06 12.8 0.0 1.9 2 0 0 2 2 2 0 SAP domain Rio2_N PF09202.6 CCU98280.1 - 1e-32 112.0 0.1 2e-32 111.1 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal RIO1 PF01163.17 CCU98280.1 - 3.3e-28 98.3 5.4 4.6e-15 55.4 1.4 3.2 2 1 0 2 2 2 2 RIO1 family zf-DHHC PF01529.15 CCU98280.1 - 5.9e-05 22.5 4.4 0.0072 15.7 1.2 2.7 2 1 1 3 3 3 2 DHHC palmitoyltransferase MarR_2 PF12802.2 CCU98280.1 - 0.0029 17.2 0.1 0.018 14.7 0.0 2.2 2 0 0 2 2 2 1 MarR family DUF2890 PF11081.3 CCU98280.1 - 0.081 12.9 16.0 0.26 11.2 11.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 CCU98280.1 - 0.12 10.8 23.0 0.21 10.0 15.9 1.3 1 0 0 1 1 1 0 Daxx Family Vfa1 PF08432.5 CCU98280.1 - 0.16 11.9 7.8 0.29 11.1 5.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 CCU98280.1 - 1.3 6.9 18.6 2.3 6.1 12.9 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2146 PF10220.4 CCU98280.1 - 1.4 6.7 9.1 2 6.3 6.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Cellulose_synt PF03552.9 CCU98280.1 - 3.8 5.6 4.2 2 6.6 1.3 1.5 1 1 1 2 2 2 0 Cellulose synthase Lin-8 PF03353.10 CCU98280.1 - 4.7 6.3 13.4 9.4 5.4 9.3 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Osteopontin PF00865.13 CCU98280.1 - 7.3 5.7 29.4 0.036 13.2 13.9 1.8 2 0 0 2 2 2 0 Osteopontin Mre11_DNA_bind PF04152.9 CCU98282.1 - 2e-36 125.4 0.1 9.4e-36 123.2 0.0 1.9 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CCU98282.1 - 7.1e-16 58.1 0.0 1.1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCU98282.1 - 1.4e-05 25.0 0.0 3.7e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Rcd1 PF04078.8 CCU98283.1 - 2.4e-128 426.5 1.8 3e-128 426.2 1.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like cwf21 PF08312.7 CCU98284.1 - 2.7e-16 59.1 8.3 5.7e-16 58.0 5.7 1.6 1 0 0 1 1 1 1 cwf21 domain PMM PF03332.8 CCU98285.1 - 1.2e-99 332.3 0.1 1.4e-99 332.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 CCU98285.1 - 1.2e-07 31.5 0.0 6.1e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CCU98285.1 - 0.0015 17.8 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.8 CCU98285.1 - 0.021 13.8 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein HAD PF12710.2 CCU98285.1 - 0.069 13.3 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCU98285.1 - 0.11 12.8 0.0 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FliX PF10768.4 CCU98285.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Class II flagellar assembly regulator PPR_2 PF13041.1 CCU98288.1 - 6.1e-31 106.1 0.0 1.7e-06 27.8 0.0 7.5 5 1 3 8 8 8 7 PPR repeat family PPR_1 PF12854.2 CCU98288.1 - 1.9e-20 72.0 0.3 0.0019 17.6 0.0 7.3 8 0 0 8 8 8 5 PPR repeat PPR PF01535.15 CCU98288.1 - 1.1e-16 59.5 0.1 0.01 15.7 0.0 7.7 8 0 0 8 8 8 3 PPR repeat PPR_3 PF13812.1 CCU98288.1 - 3.3e-12 45.6 29.3 0.011 15.9 0.4 10.5 13 0 0 13 13 13 6 Pentatricopeptide repeat domain Acetyltransf_7 PF13508.1 CCU98289.1 - 6.3e-13 48.7 0.0 5.2e-05 23.3 0.0 3.1 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCU98289.1 - 6.4e-13 48.5 0.8 4.5e-07 29.8 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCU98289.1 - 1.2e-10 41.4 0.4 0.00056 20.0 0.0 3.1 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 CCU98289.1 - 5.9e-08 33.2 0.1 3.5e-06 27.5 0.1 2.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCU98289.1 - 3.9e-07 29.7 0.4 0.0089 15.7 0.0 3.2 2 1 0 2 2 2 2 FR47-like protein GNAT_acetyltr_2 PF13718.1 CCU98289.1 - 4.4e-06 26.1 0.3 0.059 12.6 0.1 2.7 2 1 0 2 2 2 2 GNAT acetyltransferase 2 Acetyltransf_9 PF13527.1 CCU98289.1 - 3.2e-05 23.7 0.2 2.5 7.9 0.0 3.7 4 0 0 4 4 4 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCU98289.1 - 0.15 11.9 0.7 0.66 9.9 0.0 2.4 3 0 0 3 3 3 0 GCN5-related N-acetyl-transferase CHCH PF06747.8 CCU98290.1 - 4.3e-05 23.3 1.1 5.8e-05 22.8 0.8 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 CCU98290.1 - 0.049 13.3 0.5 0.067 12.9 0.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.6 CCU98290.1 - 0.055 13.5 0.6 0.075 13.1 0.4 1.2 1 0 0 1 1 1 0 GCK domain DUF1903 PF08991.5 CCU98290.1 - 0.088 12.9 0.4 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Sec61_beta PF03911.11 CCU98291.1 - 0.0014 18.4 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Sec61beta family Fucose_iso_C PF02952.12 CCU98291.1 - 0.1 12.0 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain Svf1 PF08622.5 CCU98292.1 - 2.6e-87 292.8 0.0 3.2e-87 292.5 0.0 1.1 1 0 0 1 1 1 1 Svf1-like Hus1 PF04005.7 CCU98293.1 - 1.5e-25 89.7 0.0 2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein PH PF00169.24 CCU98294.1 - 1.1e-28 99.4 0.0 6.6e-14 51.9 0.0 2.7 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 CCU98294.1 - 6.3e-17 61.8 4.2 1.9e-05 24.9 0.2 4.1 3 1 1 4 4 4 4 Pleckstrin homology domain PH_8 PF15409.1 CCU98294.1 - 1.6e-07 31.2 1.8 0.00035 20.5 0.0 3.0 4 0 0 4 4 4 2 Pleckstrin homology domain PH_3 PF14593.1 CCU98294.1 - 5.2e-07 29.4 0.2 0.59 10.0 0.0 3.3 3 0 0 3 3 3 3 PH domain Mcp5_PH PF12814.2 CCU98294.1 - 1.6e-06 28.0 3.6 0.036 13.9 0.0 3.5 3 1 0 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 CCU98294.1 - 0.0014 18.8 0.4 17 5.5 0.0 3.8 4 0 0 4 4 4 1 Pleckstrin homology domain PH_4 PF15404.1 CCU98294.1 - 0.03 13.8 0.2 23 4.4 0.0 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain PH_7 PF15408.1 CCU98294.1 - 0.067 13.0 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Apc5 PF12862.2 CCU98295.1 - 3.2e-12 46.1 0.6 1e-11 44.5 0.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 HATPase_c_2 PF13581.1 CCU98295.1 - 0.093 12.5 0.5 18 5.1 0.0 2.8 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain TPR_12 PF13424.1 CCU98295.1 - 9.5 6.2 13.1 0.1 12.5 0.5 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-CCCH PF00642.19 CCU98296.1 - 1.5e-11 43.6 37.3 0.0027 17.3 1.5 5.2 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HECT PF00632.20 CCU98297.1 - 1.2e-45 156.0 0.0 1.6e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3292 PF11696.3 CCU98298.1 - 0.0049 14.7 4.6 0.027 12.3 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3292) PRT_C PF08372.5 CCU98298.1 - 0.012 15.1 0.5 0.038 13.5 0.4 1.8 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.12 CCU98298.1 - 1 8.9 10.8 3.7 7.1 7.4 1.9 1 1 0 1 1 1 0 Reticulon Nucleo_P87 PF07267.6 CCU98298.1 - 2.9 6.4 4.3 4.8 5.7 3.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TauE PF01925.14 CCU98298.1 - 9.7 5.5 13.7 5.4 6.4 0.6 2.8 3 0 0 3 3 3 0 Sulfite exporter TauE/SafE NAP PF00956.13 CCU98299.1 - 1.2e-32 113.0 12.4 7.3e-32 110.4 8.6 1.9 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Voldacs PF03517.8 CCU98299.1 - 0.0063 16.3 5.9 0.0086 15.9 4.1 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling BUD22 PF09073.5 CCU98299.1 - 0.28 10.1 11.1 0.44 9.5 7.7 1.3 1 0 0 1 1 1 0 BUD22 ANAPC15 PF15243.1 CCU98299.1 - 0.34 10.9 12.6 18 5.4 7.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 YL1 PF05764.8 CCU98299.1 - 0.62 9.6 12.5 0.92 9.0 8.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.7 CCU98299.1 - 0.96 8.6 12.3 1.2 8.2 8.5 1.2 1 0 0 1 1 1 0 SDA1 Myc_N PF01056.13 CCU98299.1 - 1.5 7.9 10.9 0.11 11.6 3.9 1.7 2 0 0 2 2 2 0 Myc amino-terminal region DUF4611 PF15387.1 CCU98299.1 - 3.8 7.7 15.5 1.2 9.3 5.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nop14 PF04147.7 CCU98299.1 - 8.7 4.1 17.2 12 3.7 11.9 1.2 1 0 0 1 1 1 0 Nop14-like family C2 PF00168.25 CCU98300.1 - 5.3e-42 141.5 0.1 1.6e-14 53.5 0.0 4.5 4 0 0 4 4 4 4 C2 domain DUF2404 PF10296.4 CCU98300.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) NT-C2 PF10358.4 CCU98300.1 - 0.27 10.7 0.0 29 4.1 0.0 2.9 3 0 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins Ank_2 PF12796.2 CCU98301.1 - 1.1e-32 112.1 0.0 1.3e-21 76.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCU98301.1 - 8.6e-22 75.8 2.5 1e-07 31.3 0.2 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 CCU98301.1 - 1.2e-16 59.1 0.3 0.00012 21.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 CCU98301.1 - 3.3e-16 59.3 0.0 7.1e-08 32.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCU98301.1 - 5.5e-11 42.3 0.9 2.7e-06 27.4 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Arm PF00514.18 CCU98302.1 - 3.8e-93 302.4 12.1 3.2e-13 48.9 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CCU98302.1 - 8.1e-23 80.5 0.1 4.4e-08 33.2 0.0 5.9 1 1 5 6 6 6 5 HEAT repeats IBB PF01749.15 CCU98302.1 - 2e-21 75.9 5.1 3.2e-21 75.2 3.5 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 CCU98302.1 - 1e-19 70.4 1.3 1.1e-06 28.9 0.0 6.2 5 1 0 6 6 6 2 HEAT-like repeat HEAT PF02985.17 CCU98302.1 - 1.7e-17 61.8 0.7 0.00012 21.8 0.0 7.4 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.8 CCU98302.1 - 1e-07 31.3 0.0 0.0098 15.0 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 CCU98302.1 - 0.00013 20.4 0.0 0.0038 15.6 0.0 2.6 1 1 1 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.1 CCU98302.1 - 0.00055 19.8 4.9 0.1 12.5 0.1 4.2 3 2 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 CCU98302.1 - 0.002 18.0 0.0 2.2 8.2 0.0 4.4 3 2 1 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 CCU98302.1 - 0.0093 16.3 1.1 1.5 9.4 0.0 4.3 4 0 0 4 4 3 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 CCU98302.1 - 0.018 13.3 0.0 0.29 9.3 0.0 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Ric8 PF10165.4 CCU98302.1 - 0.064 12.0 0.0 0.5 9.1 0.0 2.3 2 1 1 3 3 3 0 Guanine nucleotide exchange factor synembryn Mo25 PF08569.6 CCU98302.1 - 0.14 11.2 0.0 0.32 10.0 0.0 1.6 1 0 0 1 1 1 0 Mo25-like PRP3 PF08572.5 CCU98303.1 - 8.7e-57 192.0 5.1 1.6e-56 191.1 3.6 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CCU98303.1 - 1.6e-31 108.6 0.0 4.6e-31 107.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DUF2618 PF10940.3 CCU98303.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) TRAUB PF08164.7 CCU98304.1 - 1.3e-22 79.7 2.7 5.3e-22 77.7 0.0 2.9 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 CCU98304.1 - 2e-17 63.5 0.5 2e-17 63.5 0.3 2.8 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor Nop14 PF04147.7 CCU98304.1 - 0.77 7.6 37.0 1.1 7.0 25.6 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CCU98304.1 - 0.87 7.9 35.7 0.17 10.3 22.1 1.6 1 1 0 1 1 1 0 Daxx Family Hid1 PF12722.2 CCU98304.1 - 9.4 3.7 9.2 12 3.3 6.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GTP_cyclohydro2 PF00925.15 CCU98305.1 - 1.3e-62 209.9 1.2 1.4e-56 190.3 0.0 2.8 3 0 0 3 3 3 2 GTP cyclohydrolase II LRR_6 PF13516.1 CCU98306.1 - 0.0037 17.1 0.2 0.16 12.0 0.0 3.3 3 1 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.28 CCU98306.1 - 0.0039 17.0 0.3 0.63 10.2 0.0 3.8 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_7 PF13504.1 CCU98306.1 - 0.013 15.5 0.1 1.1 9.7 0.0 3.7 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 CCU98306.1 - 0.081 12.5 0.0 3.1 7.5 0.0 3.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 CCU98306.1 - 0.25 11.1 1.9 0.72 9.6 1.3 1.9 1 1 0 1 1 1 0 F-box-like Abhydrolase_5 PF12695.2 CCU98307.1 - 3.1e-17 62.6 0.0 4.6e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCU98307.1 - 2.6e-13 50.3 0.0 5.7e-13 49.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CCU98307.1 - 1e-07 31.7 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 CCU98307.1 - 8.3e-07 28.7 0.1 5.7e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 CCU98307.1 - 0.0029 17.0 0.1 1.1 8.6 0.0 2.7 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.15 CCU98307.1 - 0.017 14.5 0.0 0.039 13.3 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.3 CCU98307.1 - 0.02 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_9 PF10081.4 CCU98307.1 - 0.059 12.0 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Thioesterase PF00975.15 CCU98307.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain FDX-ACB PF03147.9 CCU98308.1 - 3.1e-27 94.5 0.1 7e-27 93.4 0.0 1.6 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2d PF01409.15 CCU98308.1 - 2.2e-26 92.5 0.0 4.2e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) HrpB7 PF09486.5 CCU98309.1 - 0.2 11.5 4.5 0.74 9.7 0.1 2.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) DOT1 PF08123.8 CCU98310.1 - 3.4e-29 101.6 0.0 4.3e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 CCU98310.1 - 0.077 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 CCU98311.1 - 2.6e-41 141.4 0.3 3e-20 72.4 0.5 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98311.1 - 5.5e-10 38.7 3.2 7.5e-10 38.3 0.2 2.3 2 1 1 3 3 3 1 Protein tyrosine kinase PigN PF04987.9 CCU98312.1 - 6.2e-85 285.4 17.9 1.8e-81 274.0 11.4 2.1 2 0 0 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 CCU98312.1 - 4e-12 46.1 0.1 6e-08 32.4 0.0 3.1 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CCU98312.1 - 3.4e-06 26.4 0.1 5.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 CCU98312.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Not1 PF04054.10 CCU98313.1 - 3.9e-94 315.6 0.0 1.1e-93 314.1 0.0 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CCU98313.1 - 1.6e-54 183.6 2.1 7.2e-54 181.4 1.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) ABC_membrane PF00664.18 CCU98314.1 - 1.1e-23 83.9 5.3 1.7e-23 83.4 3.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CCU98314.1 - 3.4e-10 40.3 0.0 1.1e-09 38.7 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane_2 PF06472.10 CCU98314.1 - 0.0015 17.7 0.6 0.0015 17.7 0.4 2.5 4 0 0 4 4 4 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.7 CCU98314.1 - 0.14 11.2 4.2 1.2 8.2 0.1 2.3 2 0 0 2 2 2 0 SbmA/BacA-like family ABC_tran PF00005.22 CCU98315.1 - 1.7e-30 106.1 0.0 2.2e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CCU98315.1 - 6.5e-07 28.8 0.0 0.00028 20.1 0.0 2.0 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCU98315.1 - 3.6e-05 23.8 0.3 0.039 13.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCU98315.1 - 4.9e-05 23.3 0.2 8e-05 22.6 0.2 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 CCU98315.1 - 0.00024 20.6 0.3 0.042 13.2 0.0 2.0 1 1 1 2 2 2 2 AAA-like domain AAA_22 PF13401.1 CCU98315.1 - 0.00043 20.4 0.3 0.014 15.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CCU98315.1 - 0.0023 17.3 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 CCU98315.1 - 0.0059 16.0 0.1 2.1 7.7 0.1 2.1 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 CCU98315.1 - 0.0079 15.6 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCU98315.1 - 0.019 15.7 0.0 0.038 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 CCU98315.1 - 0.028 14.2 0.4 0.078 12.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 CCU98315.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 CCU98315.1 - 0.043 12.7 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 CCU98315.1 - 0.089 12.4 0.1 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 NTPase MobB PF03205.9 CCU98315.1 - 0.13 11.9 0.1 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 CCU98315.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Aminotran_4 PF01063.14 CCU98316.1 - 6.5e-26 91.2 0.0 1.1e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV WD40 PF00400.27 CCU98317.1 - 1.2e-07 31.3 7.0 0.006 16.4 0.1 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat DEAD PF00270.24 CCU98318.1 - 1.4e-42 145.0 0.0 3.1e-41 140.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU98318.1 - 2.5e-14 52.8 0.0 5.8e-13 48.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCU98318.1 - 0.00067 19.5 6.2 0.00096 19.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CCU98318.1 - 0.033 13.2 0.0 0.033 13.2 0.0 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit CH PF00307.26 CCU98319.1 - 3.2e-67 223.3 0.1 1.8e-17 63.3 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CCU98319.1 - 4.9e-09 35.7 0.0 0.19 11.4 0.0 4.4 4 0 0 4 4 4 4 CAMSAP CH domain EF-hand_7 PF13499.1 CCU98319.1 - 0.034 14.2 2.9 0.068 13.3 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain pair SPX PF03105.14 CCU98320.1 - 2.7e-20 73.3 0.0 4.1e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 CCU98320.1 - 5.3e-07 28.8 13.7 3.8e-06 26.0 5.9 2.1 1 1 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CCU98320.1 - 2.1e-05 23.2 17.5 0.012 14.1 1.3 2.1 1 1 1 2 2 2 2 Citrate transporter PseudoU_synth_1 PF01416.15 CCU98321.1 - 5e-26 91.1 0.0 2.6e-14 53.5 0.0 2.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase Hox9_act PF04617.8 CCU98321.1 - 0.067 13.3 0.2 6.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Hox9 activation region SET PF00856.23 CCU98322.1 - 1.9e-08 34.8 0.0 9.8e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 SET domain NUDIX PF00293.23 CCU98323.1 - 3.4e-23 81.7 0.0 4.8e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Asp PF00026.18 CCU98324.1 - 1.7e-42 145.8 10.0 5.6e-42 144.0 6.9 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCU98324.1 - 1.7e-09 38.0 1.8 1.6e-05 25.2 0.2 2.4 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 CCU98324.1 - 0.00086 18.8 0.1 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 CCU98324.1 - 0.0067 16.3 0.7 0.016 15.1 0.5 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 CCU98324.1 - 0.034 13.9 0.6 0.17 11.6 0.1 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DAHP_synth_2 PF01474.11 CCU98325.1 - 9.5e-181 600.9 0.0 1.1e-180 600.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Sec34 PF04136.10 CCU98326.1 - 2.2e-14 53.4 0.1 4.5e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Sec34-like family DUF972 PF06156.8 CCU98326.1 - 0.11 12.8 0.4 30 5.0 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Ribosomal_L6 PF00347.18 CCU98328.1 - 7.4e-25 87.2 2.2 5.9e-15 55.5 0.1 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L37e PF01907.14 CCU98329.1 - 3.8e-07 29.8 3.8 3.8e-07 29.8 2.6 2.3 2 1 1 3 3 3 1 Ribosomal protein L37e DUF1462 PF07315.6 CCU98329.1 - 0.033 14.1 0.0 0.037 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Ribosomal_L7Ae PF01248.21 CCU98330.1 - 8.8e-24 82.8 0.0 1e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FKBP_C PF00254.23 CCU98330.1 - 0.038 13.9 0.0 0.08 12.9 0.0 1.5 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase Cyclin_N PF00134.18 CCU98331.1 - 6.1e-21 74.3 0.1 9.5e-21 73.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain MBF1 PF08523.5 CCU98333.1 - 9.4e-14 51.1 0.2 1.6e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 CCU98333.1 - 2.6e-12 46.4 0.2 4e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 CCU98333.1 - 5.6e-08 32.7 0.1 7.4e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 CCU98333.1 - 2e-06 27.9 0.0 3.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Pkinase PF00069.20 CCU98334.1 - 5.6e-62 209.2 0.0 7.8e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98334.1 - 1.1e-31 109.8 0.0 9.1e-30 103.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU98334.1 - 5.5e-08 32.1 0.0 8.7e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCU98334.1 - 0.0011 18.0 0.0 0.0032 16.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCU98334.1 - 0.009 15.7 0.1 1.5 8.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family JAB PF01398.16 CCU98335.1 - 9.7e-20 70.4 0.0 1.9e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CCU98335.1 - 1.6e-11 44.2 0.1 3.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prefoldin_2 PF01920.15 CCU98335.1 - 0.031 14.0 0.1 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit Methyltransf_4 PF02390.12 CCU98336.1 - 3.8e-54 182.7 0.0 1.5e-40 138.3 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.9 CCU98336.1 - 0.00051 19.4 0.0 0.0034 16.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CCU98336.1 - 0.0014 19.1 0.0 0.0041 17.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCU98336.1 - 0.0028 17.9 0.0 0.01 16.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCU98336.1 - 0.0036 17.3 0.0 0.0093 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCU98336.1 - 0.0061 17.1 0.0 0.019 15.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 CCU98336.1 - 0.036 13.0 0.0 0.066 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.7 CCU98336.1 - 0.048 14.1 0.0 3.8 8.0 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 CCU98336.1 - 0.091 12.3 0.0 1.1 8.8 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain DUF3492 PF11997.3 CCU98337.1 - 0.021 14.4 0.0 0.023 14.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) NDUFB10 PF10249.4 CCU98337.1 - 0.026 14.6 0.2 0.028 14.5 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Zw10 PF06248.8 CCU98337.1 - 0.078 11.1 0.2 0.082 11.0 0.1 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Prefoldin_2 PF01920.15 CCU98338.1 - 9.6e-18 63.8 7.5 1.1e-17 63.6 5.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 CCU98338.1 - 0.0012 18.4 5.8 0.0023 17.5 4.1 1.3 1 1 0 1 1 1 1 Prefoldin subunit PhoU_div PF01865.11 CCU98338.1 - 0.0081 15.3 3.0 0.13 11.4 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF47 NOC3p PF07540.6 CCU98338.1 - 0.044 14.0 1.2 0.096 12.9 0.8 1.6 1 1 0 1 1 1 0 Nucleolar complex-associated protein DUF77 PF01910.12 CCU98338.1 - 0.045 13.4 0.4 1 9.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF77 APG6 PF04111.7 CCU98338.1 - 0.07 12.1 3.9 0.078 12.0 2.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Mito_fiss_reg PF05308.6 CCU98338.1 - 0.094 12.0 0.2 0.12 11.7 0.2 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator Penicillinase_R PF03965.11 CCU98338.1 - 0.099 12.7 0.6 0.099 12.7 0.4 1.6 2 0 0 2 2 2 0 Penicillinase repressor IFT57 PF10498.4 CCU98338.1 - 0.36 9.5 6.1 0.84 8.3 1.0 2.0 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 ADIP PF11559.3 CCU98338.1 - 0.63 9.9 4.9 0.48 10.3 0.5 2.0 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding SbcD_C PF12320.3 CCU98338.1 - 1.1 9.2 5.5 2.7 8.0 3.6 1.7 1 1 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain DUF641 PF04859.7 CCU98338.1 - 1.2 8.9 6.2 0.74 9.5 0.9 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ATG16 PF08614.6 CCU98338.1 - 6.3 6.5 8.7 1.6 8.5 1.4 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 CCU98338.1 - 9.4 5.7 9.0 57 3.2 6.2 1.9 1 1 0 1 1 1 0 IncA protein PC_rep PF01851.17 CCU98339.1 - 2e-46 153.6 22.7 1e-08 34.9 0.1 10.8 11 0 0 11 11 11 9 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CCU98339.1 - 1.7e-19 69.8 11.1 4.3e-11 42.9 0.0 5.5 4 1 2 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 CCU98339.1 - 8.1e-08 32.5 7.5 0.04 14.4 0.1 6.2 4 1 2 6 6 6 3 HEAT-like repeat HEAT PF02985.17 CCU98339.1 - 7.5e-06 25.5 1.3 4.2 7.7 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_PBS PF03130.11 CCU98339.1 - 0.92 10.1 12.0 78 4.1 0.0 5.8 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Actin PF00022.14 CCU98341.1 - 9.5e-22 76.9 0.0 2.2e-21 75.7 0.0 1.6 1 1 0 1 1 1 1 Actin Pyridox_ox_2 PF12900.2 CCU98341.1 - 0.0027 17.5 0.2 0.0072 16.1 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase PGM_PMM_I PF02878.11 CCU98342.1 - 4.2e-15 55.4 0.1 2.5e-08 33.4 0.0 2.8 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CCU98342.1 - 6.9e-13 48.8 0.0 2.8e-12 46.8 0.0 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CCU98342.1 - 1.8e-09 37.4 0.1 3.9e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 CCU98342.1 - 0.00046 20.1 0.4 0.0015 18.5 0.3 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III POR_N PF01855.14 CCU98342.1 - 0.077 12.4 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg MR_MLE_C PF13378.1 CCU98342.1 - 0.1 12.5 4.0 0.094 12.6 1.1 2.4 3 0 0 3 3 3 0 Enolase C-terminal domain-like PQ-loop PF04193.9 CCU98343.1 - 2.2e-24 84.7 4.0 4e-13 48.6 0.2 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 CCU98343.1 - 0.00063 19.5 3.9 0.011 15.6 0.5 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Cytochrom_B_C PF00032.12 CCU98343.1 - 0.78 9.9 4.1 1.5 9.0 0.6 2.4 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD MFS_1 PF07690.11 CCU98344.1 - 1.7e-09 36.8 21.3 2.5e-09 36.3 14.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily BESS PF02944.15 CCU98344.1 - 0.25 10.9 2.0 0.42 10.2 0.1 2.3 3 0 0 3 3 3 0 BESS motif JAB PF01398.16 CCU98345.1 - 4.2e-09 36.1 0.0 7.5e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HCV_NS2 PF01538.13 CCU98345.1 - 0.13 11.7 0.2 0.3 10.4 0.1 1.6 1 1 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 LAG1-DNAbind PF09271.6 CCU98347.1 - 3.8e-22 79.2 0.0 8.5e-21 74.8 0.0 2.2 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 CCU98347.1 - 1e-20 74.0 0.0 2.1e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF501 PF04417.7 CCU98347.1 - 0.0015 18.3 0.2 0.0033 17.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF501) RseA_C PF03873.8 CCU98347.1 - 0.12 12.3 1.0 0.3 11.0 0.7 1.8 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain DUF566 PF04484.7 CCU98347.1 - 1.9 7.9 9.2 3.6 6.9 6.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) Las1 PF04031.8 CCU98348.1 - 5.6e-44 149.5 0.4 1.5e-43 148.1 0.0 1.8 2 0 0 2 2 2 1 Las1-like SAICAR_synt PF01259.13 CCU98349.1 - 4e-74 248.8 0.0 5.4e-74 248.4 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Kinesin PF00225.18 CCU98350.1 - 2.6e-101 338.6 0.0 4.4e-101 337.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain WD40 PF00400.27 CCU98351.1 - 7.2e-57 187.3 25.5 7.9e-13 47.7 0.1 7.4 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 CCU98351.1 - 1.4e-07 31.4 0.0 0.00018 21.2 0.0 3.6 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCU98351.1 - 0.008 14.3 6.9 0.72 7.9 0.0 3.4 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Kelch_6 PF13964.1 CCU98351.1 - 0.012 15.7 0.0 0.12 12.6 0.0 2.6 3 0 0 3 3 3 0 Kelch motif Nucleoporin_N PF08801.6 CCU98351.1 - 0.026 13.2 0.3 1.7 7.2 0.1 2.9 1 1 1 2 2 2 0 Nup133 N terminal like Nbas_N PF15492.1 CCU98351.1 - 0.14 11.2 2.2 7.2 5.6 0.1 3.4 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 CCU98351.1 - 0.17 10.0 0.2 0.52 8.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Aminotran_1_2 PF00155.16 CCU98353.1 - 2.2e-47 161.7 0.0 3.9e-47 160.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCU98353.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 CCU98353.1 - 0.026 12.8 0.0 0.059 11.6 0.0 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3818 PF12825.2 CCU98354.1 - 1.7e-40 138.7 0.0 1.7e-40 138.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CCU98354.1 - 6.7e-16 58.1 0.5 2.4e-15 56.3 0.4 1.9 1 0 0 1 1 1 1 PX-associated DUF3500 PF12006.3 CCU98354.1 - 0.012 14.5 0.9 0.06 12.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3500) DUF2433 PF10360.4 CCU98355.1 - 1.9e-29 102.6 0.0 5e-29 101.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_6 PF14259.1 CCU98355.1 - 0.00028 20.8 0.0 0.00059 19.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Metallophos_2 PF12850.2 CCU98355.1 - 0.00098 18.9 0.0 0.0079 16.0 0.0 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CCU98355.1 - 0.004 16.5 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_1 PF00076.17 CCU98355.1 - 0.0066 16.0 0.0 0.042 13.4 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU PF00009.22 CCU98356.1 - 3.2e-34 118.0 0.0 9e-34 116.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CCU98356.1 - 1.9e-16 59.8 0.0 4.5e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CCU98356.1 - 7.7e-16 57.9 4.2 6.3e-11 42.2 0.1 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCU98356.1 - 1.3e-05 25.1 0.0 3.6e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CCU98356.1 - 0.00089 18.8 0.0 0.0021 17.6 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Miro PF08477.8 CCU98356.1 - 0.0073 16.7 0.5 0.022 15.2 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 CCU98356.1 - 0.0098 15.7 0.2 0.0098 15.7 0.1 3.1 3 0 0 3 3 3 1 Dynamin family AAA_22 PF13401.1 CCU98356.1 - 0.045 13.8 0.1 0.24 11.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 CCU98356.1 - 0.084 12.2 0.0 0.28 10.5 0.0 1.9 1 1 0 1 1 1 0 Ras family DUF2611 PF11022.3 CCU98359.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2611) MAM33 PF02330.11 CCU98360.1 - 7.4e-34 117.3 0.7 8.7e-34 117.0 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein RICTOR_M PF14666.1 CCU98362.1 - 9.7e-57 191.5 0.3 3.2e-56 189.8 0.1 1.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 CCU98362.1 - 5.8e-26 90.9 0.4 2e-20 72.7 0.2 3.6 1 1 1 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.1 CCU98362.1 - 1.1e-20 73.2 0.2 1.3e-18 66.7 0.2 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.1 CCU98362.1 - 1.2e-08 34.8 0.0 4.8e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.18 CCU98362.1 - 0.0045 16.7 1.8 0.044 13.6 0.0 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF3628 PF12300.3 CCU98364.1 - 0.076 13.0 8.1 0.18 11.8 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Serglycin PF04360.7 CCU98364.1 - 2.6 7.7 13.6 9 6.0 9.4 1.9 1 1 0 1 1 1 0 Serglycin PsbX PF06596.6 CCU98364.1 - 2.9 7.6 4.8 0.41 10.3 0.3 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Methyltransf_28 PF02636.12 CCU98365.1 - 7.4e-34 117.2 0.0 1.5e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MMgT PF10270.4 CCU98365.1 - 1.5e-12 47.8 0.0 3.1e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Membrane magnesium transporter Methyltransf_12 PF08242.7 CCU98365.1 - 0.0018 18.7 0.0 0.0077 16.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCU98365.1 - 0.018 15.0 0.0 0.063 13.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 CCU98365.1 - 0.03 13.3 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Actin PF00022.14 CCU98366.1 - 4.7e-158 525.7 0.0 5.3e-158 525.5 0.0 1.0 1 0 0 1 1 1 1 Actin Methyltransf_29 PF03141.11 CCU98366.1 - 0.0036 15.6 0.0 0.0053 15.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase ESSS PF10183.4 CCU98366.1 - 0.09 13.1 0.0 0.23 11.8 0.0 1.6 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Nop PF01798.13 CCU98367.1 - 3.9e-60 201.4 0.1 8.6e-60 200.3 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CCU98367.1 - 2.4e-26 91.2 0.2 7e-26 89.7 0.0 1.9 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CCU98367.1 - 1.9e-19 69.5 0.1 1.9e-19 69.5 0.1 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain BCDHK_Adom3 PF10436.4 CCU98367.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Na_trans_assoc PF06512.8 CCU98367.1 - 0.31 10.9 13.8 0.58 10.0 9.6 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Proteasome PF00227.21 CCU98368.1 - 5.1e-46 156.3 0.2 1.5e-44 151.5 0.1 2.3 2 1 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 CCU98368.1 - 3.4e-15 55.0 0.8 5.2e-15 54.4 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SecM PF06558.7 CCU98368.1 - 0.034 13.7 0.1 0.063 12.9 0.1 1.4 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) FANCI_S1-cap PF14674.1 CCU98368.1 - 0.15 12.1 0.4 4.4 7.4 0.0 2.5 2 0 0 2 2 2 0 FANCI solenoid 1 cap TPR_11 PF13414.1 CCU98369.1 - 2.8e-08 33.2 48.0 0.0099 15.5 0.1 10.6 7 3 5 12 12 12 5 TPR repeat TPR_16 PF13432.1 CCU98369.1 - 1.7e-05 25.3 17.5 0.00011 22.7 2.4 14.3 8 6 7 15 15 15 4 Tetratricopeptide repeat TPR_2 PF07719.12 CCU98369.1 - 4.9e-05 22.9 48.1 0.012 15.4 0.0 11.9 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCU98369.1 - 7.1e-05 22.2 15.5 0.1 12.2 0.0 7.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCU98369.1 - 7.5e-05 22.9 22.6 0.0023 18.2 0.1 9.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCU98369.1 - 0.00043 20.6 11.7 0.00062 20.1 2.3 17.0 12 4 5 17 17 17 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCU98369.1 - 0.0089 15.7 0.0 16 5.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCU98369.1 - 0.011 15.8 13.6 8.6 6.8 0.0 8.7 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCU98369.1 - 0.29 11.4 0.0 0.081 13.2 1.1 13.6 13 4 0 14 14 14 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCU98369.1 - 0.97 9.3 18.8 0.6 10.0 0.3 7.1 6 0 0 6 6 6 0 Tetratricopeptide repeat SNO PF01174.14 CCU98370.1 - 1.7e-50 171.2 0.0 1.9e-47 161.3 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 CCU98370.1 - 2e-11 43.7 0.1 4.1e-11 42.7 0.1 1.5 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 CCU98370.1 - 2.4e-05 23.8 0.1 0.00089 18.7 0.1 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 CCU98370.1 - 5.6e-05 22.9 0.0 8.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.19 CCU98370.1 - 0.0002 20.8 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CCU98370.1 - 0.004 16.4 0.1 0.006 15.8 0.1 1.2 1 0 0 1 1 1 1 Putative amidotransferase BPL_N PF09825.4 CCU98370.1 - 0.034 12.9 0.0 0.17 10.6 0.0 1.8 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal DUF4154 PF13689.1 CCU98370.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) Peptidase_C26 PF07722.8 CCU98370.1 - 0.083 12.3 0.1 1.1 8.6 0.0 2.4 3 0 0 3 3 3 0 Peptidase C26 MT-A70 PF05063.9 CCU98371.1 - 4.8e-12 45.7 0.0 7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Cpn60_TCP1 PF00118.19 CCU98372.1 - 1.4e-138 462.5 7.1 1.6e-138 462.3 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family COX4 PF02936.9 CCU98373.1 - 3.1e-25 88.5 1.2 7.6e-24 84.0 0.4 2.4 2 1 0 2 2 2 1 Cytochrome c oxidase subunit IV HMG_box_5 PF14887.1 CCU98373.1 - 0.07 12.9 0.3 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Cys_Met_Meta_PP PF01053.15 CCU98374.1 - 1.7e-142 474.3 0.0 2e-142 474.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CCU98374.1 - 1.1e-12 47.7 0.1 2.7e-12 46.4 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CCU98374.1 - 1.3e-10 40.5 0.3 1.5e-09 37.1 0.1 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CCU98374.1 - 4.2e-10 39.1 0.0 5.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCU98374.1 - 9.3e-09 34.8 0.0 4.2e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase Aldo_ket_red PF00248.16 CCU98374.1 - 0.006 15.4 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Met_gamma_lyase PF06838.6 CCU98374.1 - 0.066 11.5 0.3 0.28 9.4 0.2 1.9 1 1 0 1 1 1 0 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 CCU98374.1 - 0.069 11.6 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 CCU98374.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.15 CCU98375.1 - 9e-118 392.9 0.0 1.2e-117 392.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RTC PF01137.16 CCU98375.1 - 2.6e-56 189.9 0.0 4e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CCU98375.1 - 5e-31 106.7 0.1 2.8e-30 104.3 0.0 2.4 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain GHMP_kinases_N PF00288.21 CCU98375.1 - 1.7e-17 63.2 1.0 6.2e-17 61.4 0.7 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCU98375.1 - 8.3e-08 32.3 0.5 3.1e-07 30.5 0.2 2.1 1 1 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 CCU98375.1 - 0.0048 16.1 0.0 0.012 14.8 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Met_gamma_lyase PF06838.6 CCU98375.1 - 0.048 11.9 0.0 0.081 11.2 0.0 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase Aminotran_1_2 PF00155.16 CCU98375.1 - 0.054 12.4 0.0 0.094 11.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II DUF2347 PF09804.4 CCU98376.1 - 2.3e-32 112.3 0.0 6.2e-31 107.7 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 CCU98376.1 - 0.16 10.4 0.0 3 6.2 0.0 2.6 3 0 0 3 3 3 0 Transport protein Avl9 Prp19_bind PF06991.6 CCU98377.1 - 7.1e-52 176.3 7.9 9.3e-52 176.0 5.5 1.0 1 0 0 1 1 1 1 Splicing factor, Prp19-binding domain CAF-1_p150 PF11600.3 CCU98377.1 - 0.24 10.7 8.5 0.4 10.0 5.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Arf PF00025.16 CCU98378.1 - 2.3e-24 85.5 0.0 2.7e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CCU98378.1 - 2.2e-07 29.9 0.1 5.3e-07 28.6 0.0 1.5 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.5 CCU98378.1 - 5e-05 22.5 0.0 5.9e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CCU98378.1 - 0.029 13.7 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Ras family Gtr1_RagA PF04670.7 CCU98378.1 - 0.034 13.2 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCU98378.1 - 0.044 13.7 0.1 0.084 12.8 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF1501 PF07394.7 CCU98378.1 - 0.068 11.9 0.0 0.082 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Miro PF08477.8 CCU98378.1 - 0.085 13.3 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Miro-like protein NdhN PF11909.3 CCU98378.1 - 0.099 11.9 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N IpaD PF06511.6 CCU98378.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD SNF2_N PF00176.18 CCU98379.1 - 3.7e-70 236.0 0.1 6.8e-70 235.2 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCU98379.1 - 4.5e-16 58.4 0.5 1.8e-15 56.5 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCU98379.1 - 2.6e-09 37.1 0.0 9.3e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.8 CCU98379.1 - 2.5e-07 30.3 10.3 2.5e-07 30.3 7.1 3.0 2 1 1 3 3 3 1 HSA DEAD PF00270.24 CCU98379.1 - 1.2e-05 24.8 0.0 6.5e-05 22.4 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 CCU98379.1 - 0.021 13.6 0.1 6.3 5.5 0.0 2.5 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 BUD22 PF09073.5 CCU98379.1 - 0.25 10.3 25.6 0.5 9.3 17.7 1.4 1 0 0 1 1 1 0 BUD22 ATP-synt_Eps PF04627.8 CCU98380.1 - 1.5e-15 56.4 5.6 1.9e-15 56.1 3.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain CDC50 PF03381.10 CCU98382.1 - 3.3e-86 288.8 0.0 3.8e-86 288.7 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family FAM70 PF14967.1 CCU98382.1 - 0.32 10.1 2.9 0.11 11.7 0.3 1.4 2 0 0 2 2 2 0 FAM70 protein GTP_EFTU PF00009.22 CCU98383.1 - 3e-24 85.4 0.0 4.6e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCU98383.1 - 1.5e-10 41.1 0.0 4.3e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCU98383.1 - 1e-06 28.7 0.2 6.3e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCU98383.1 - 0.00099 18.7 0.1 0.0045 16.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCU98383.1 - 0.0066 16.4 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCU98383.1 - 0.071 12.3 0.1 3.8 6.7 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Miro PF08477.8 CCU98383.1 - 0.15 12.5 0.4 1.2 9.6 0.3 2.4 1 1 0 1 1 1 0 Miro-like protein Oxysterol_BP PF01237.13 CCU98385.1 - 4.5e-72 242.4 0.0 5.6e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein TPR_1 PF00515.23 CCU98386.1 - 2.5e-55 181.9 14.8 1.3e-05 24.5 0.0 10.4 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 CCU98386.1 - 3.9e-50 167.3 12.7 1.5e-12 46.9 0.0 7.0 4 2 2 7 7 7 7 TPR repeat TPR_2 PF07719.12 CCU98386.1 - 2.4e-49 161.3 9.6 3.8e-05 23.2 0.0 10.3 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 CCU98386.1 - 7.8e-40 131.6 14.1 2.2e-05 23.9 0.0 10.0 9 1 1 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.1 CCU98386.1 - 3.8e-34 114.0 3.2 0.00089 19.6 0.0 10.3 3 3 7 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 CCU98386.1 - 6.2e-28 96.5 17.1 1.3e-05 25.0 0.4 6.8 2 2 7 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.1 CCU98386.1 - 2.2e-26 89.4 12.1 0.0077 15.9 0.0 10.0 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 CCU98386.1 - 2.6e-26 91.7 9.1 1.3e-05 25.4 0.1 7.2 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 CCU98386.1 - 7e-26 88.2 13.4 0.0056 16.7 0.0 10.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 CCU98386.1 - 9.1e-24 83.5 15.1 0.003 18.1 0.1 7.6 6 1 1 8 8 7 7 Tetratricopeptide repeat TPR_6 PF13174.1 CCU98386.1 - 7.8e-21 73.0 9.2 0.0075 16.6 0.0 9.3 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 CCU98386.1 - 3.3e-15 55.7 10.6 0.00056 19.7 0.0 6.3 3 2 3 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 CCU98386.1 - 3.9e-13 49.3 7.3 0.00028 20.9 1.0 4.6 3 1 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CCU98386.1 - 8e-08 31.6 3.2 0.03 13.3 0.0 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.4 CCU98386.1 - 1.5e-05 24.9 5.6 1.4 8.8 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 CCU98386.1 - 0.0025 17.6 13.2 28 4.8 0.0 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat Tcf25 PF04910.9 CCU98386.1 - 0.0026 16.7 0.5 0.48 9.3 0.1 2.4 2 0 0 2 2 2 1 Transcriptional repressor TCF25 TPR_20 PF14561.1 CCU98386.1 - 0.013 15.5 4.0 0.26 11.4 0.1 4.2 5 1 1 6 6 4 0 Tetratricopeptide repeat DUF2225 PF09986.4 CCU98386.1 - 0.054 12.9 1.6 1.5 8.1 0.0 2.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 CCU98386.1 - 0.065 13.1 11.5 0.32 10.8 0.1 4.5 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 CCU98386.1 - 0.094 11.4 0.1 3.3 6.3 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.1 CCU98386.1 - 0.3 10.2 5.3 8.6 5.4 0.3 4.0 2 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP DUF2989 PF11207.3 CCU98386.1 - 0.38 10.1 4.1 2.1 7.7 1.2 3.0 2 1 1 4 4 4 0 Protein of unknown function (DUF2989) Foie-gras_1 PF11817.3 CCU98386.1 - 2.6 7.4 6.8 3.1 7.2 1.0 3.2 3 2 3 6 6 6 0 Foie gras liver health family 1 TPR_3 PF07720.7 CCU98386.1 - 4.4 7.2 12.9 8.2 6.3 0.6 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat SOR_SNZ PF01680.12 CCU98387.1 - 8.8e-117 388.0 5.0 8.8e-117 388.0 3.4 1.6 1 1 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 CCU98387.1 - 1.3e-06 27.7 6.1 6.6e-05 22.1 0.1 2.7 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 CCU98387.1 - 0.017 14.4 0.6 0.28 10.4 0.0 2.4 3 0 0 3 3 3 0 Histidine biosynthesis protein Trp_syntA PF00290.15 CCU98387.1 - 0.02 13.4 0.0 0.033 12.7 0.0 1.4 1 0 0 1 1 1 0 Tryptophan synthase alpha chain NanE PF04131.9 CCU98387.1 - 0.02 13.8 0.4 0.1 11.5 0.0 2.3 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 CCU98387.1 - 0.026 13.5 0.1 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Dus PF01207.12 CCU98387.1 - 0.031 13.1 0.6 4 6.1 0.0 2.4 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) NMO PF03060.10 CCU98387.1 - 0.047 12.8 5.1 0.051 12.7 0.0 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase Rieske PF00355.21 CCU98388.1 - 1.3e-17 63.0 0.0 2.2e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 CCU98388.1 - 2.2e-15 56.5 1.8 4.4e-15 55.6 1.3 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region HEAT PF02985.17 CCU98390.1 - 4.8e-07 29.3 16.1 0.23 11.6 0.0 8.9 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 CCU98390.1 - 1.3e-06 28.6 6.8 0.03 14.5 0.0 5.2 2 2 2 4 4 4 3 HEAT repeats Adaptin_N PF01602.15 CCU98390.1 - 0.034 12.4 0.0 0.14 10.4 0.0 1.9 2 0 0 2 2 2 0 Adaptin N terminal region OPT PF03169.10 CCU98391.1 - 2e-88 297.4 49.7 9.1e-83 278.7 27.2 2.6 1 1 1 2 2 2 2 OPT oligopeptide transporter protein DUF1270 PF06900.6 CCU98391.1 - 0.00057 19.9 0.7 0.00057 19.9 0.5 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1270) PDEase_II PF02112.10 CCU98392.1 - 2e-49 168.3 0.0 3.1e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 CCU98392.1 - 2.1e-09 37.2 0.0 3.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CCU98392.1 - 0.029 14.0 2.3 0.07 12.7 1.6 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Glu_synthase PF01645.12 CCU98393.1 - 1.9e-159 530.5 0.0 3.1e-159 529.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 CCU98393.1 - 2.8e-130 434.2 0.0 3.8e-130 433.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 CCU98393.1 - 1.5e-115 385.3 0.0 2.5e-115 384.7 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 CCU98393.1 - 5.8e-67 224.6 0.5 1e-66 223.8 0.3 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 CCU98393.1 - 6.4e-22 77.2 0.0 1.5e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 CCU98393.1 - 1.2e-18 67.6 0.0 5.7e-18 65.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCU98393.1 - 5.1e-11 43.0 0.1 0.00034 20.7 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCU98393.1 - 1.3e-09 37.9 0.1 5.7e-09 35.8 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCU98393.1 - 7.9e-08 32.6 0.6 0.0001 22.6 0.1 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CCU98393.1 - 5.9e-07 28.9 0.1 1e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 CCU98393.1 - 5.1e-06 25.6 1.3 3.9e-05 22.7 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCU98393.1 - 1.1e-05 24.5 0.6 0.00033 19.6 0.2 3.0 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 CCU98393.1 - 1.7e-05 23.4 0.1 1.7e-05 23.4 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 CCU98393.1 - 0.0003 20.0 1.1 0.00071 18.7 0.5 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 CCU98393.1 - 0.00039 20.6 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 CCU98393.1 - 0.00054 19.8 0.2 1.4 8.7 0.1 2.7 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_binding_3 PF01494.14 CCU98393.1 - 0.0019 17.3 0.0 0.0037 16.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CCU98393.1 - 0.011 14.8 0.3 0.03 13.3 0.2 1.7 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 CCU98393.1 - 0.032 13.8 0.1 0.78 9.2 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 CCU98393.1 - 0.06 12.4 0.0 0.41 9.7 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 CCU98393.1 - 0.077 11.8 2.6 0.14 11.0 0.3 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 CCU98393.1 - 0.079 12.6 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DJ-1_PfpI PF01965.19 CCU98393.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.7 1 0 0 1 1 1 0 DJ-1/PfpI family FMO-like PF00743.14 CCU98393.1 - 0.12 10.5 0.1 0.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 CCU98393.1 - 0.15 12.1 0.3 8 6.5 0.1 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CCU98393.1 - 5.7 6.5 5.2 0.74 9.4 0.2 2.0 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Nop PF01798.13 CCU98394.1 - 2.6e-39 133.9 0.1 4.5e-39 133.1 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 CCU98394.1 - 1.8e-35 122.0 1.9 3.1e-35 121.3 1.3 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 CCU98394.1 - 1.4e-14 53.5 0.0 2.8e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain Adenylsucc_synt PF00709.16 CCU98395.1 - 1.8e-159 530.9 0.0 2e-159 530.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase CybS PF05328.7 CCU98396.1 - 5e-33 113.5 0.2 7.2e-31 106.5 0.0 2.1 2 0 0 2 2 2 2 CybS TFIIS_C PF01096.13 CCU98397.1 - 2.1e-09 36.8 9.1 6e-09 35.3 3.2 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CCU98397.1 - 1.9e-05 24.2 0.5 1.9e-05 24.2 0.3 2.8 4 0 0 4 4 3 1 RNA polymerases M/15 Kd subunit CpXC PF14353.1 CCU98397.1 - 0.019 14.8 7.3 1 9.3 0.0 3.0 1 1 2 3 3 3 0 CpXC protein Lar_restr_allev PF14354.1 CCU98397.1 - 0.038 14.3 2.6 0.072 13.4 0.7 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 CCU98397.1 - 0.046 12.9 0.1 0.046 12.9 0.1 3.1 4 0 0 4 4 3 0 zinc-ribbon domain T4_baseplate PF12322.3 CCU98397.1 - 0.049 12.8 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 T4 bacteriophage base plate protein DUF3268 PF11672.3 CCU98397.1 - 0.051 13.6 3.6 2.3 8.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Baculo_ME53 PF06061.6 CCU98397.1 - 0.21 10.5 4.7 0.1 11.6 1.7 1.5 2 0 0 2 2 2 0 Baculoviridae ME53 zf-C2H2_4 PF13894.1 CCU98397.1 - 0.45 10.9 8.5 2 8.9 0.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Elf1 PF05129.8 CCU98397.1 - 0.54 9.9 5.0 7.4 6.3 2.9 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 CCU98397.1 - 0.61 9.8 0.2 0.61 9.8 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CCU98397.1 - 0.74 9.4 0.2 0.74 9.4 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 CCU98397.1 - 0.79 9.2 7.7 2.4 7.6 0.0 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-DNL PF05180.7 CCU98397.1 - 1.1 8.9 5.6 2.9 7.6 1.2 2.3 2 0 0 2 2 2 0 DNL zinc finger zf-IS66 PF13005.2 CCU98397.1 - 1.5 8.8 0.1 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Zn-ribbon_8 PF09723.5 CCU98397.1 - 1.8 8.5 9.5 4.2 7.3 0.0 3.2 3 0 0 3 3 3 0 Zinc ribbon domain DUF2296 PF10058.4 CCU98397.1 - 2.5 7.9 9.1 5.4 6.8 3.5 2.6 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Zn_Tnp_IS1 PF03811.8 CCU98397.1 - 5 6.7 7.9 1 8.8 1.8 2.3 2 1 0 2 2 2 0 InsA N-terminal domain E1_dh PF00676.15 CCU98398.1 - 8e-112 372.8 0.0 9.4e-112 372.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CCU98398.1 - 6.5e-05 21.9 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.16 CCU98398.1 - 0.0014 17.5 0.2 0.14 10.9 0.0 2.1 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.16 CCU98398.1 - 0.016 14.7 4.2 0.056 13.0 0.5 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NHase_beta PF02211.10 CCU98398.1 - 0.072 12.7 0.5 11 5.6 0.1 2.4 3 0 0 3 3 3 0 Nitrile hydratase beta subunit Pribosyltran PF00156.22 CCU98399.1 - 8.8e-08 31.9 0.1 1.9e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF962 PF06127.6 CCU98400.1 - 1.8e-22 79.0 2.8 1.9e-21 75.7 2.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) UPF0197 PF05251.7 CCU98400.1 - 1.5 9.1 6.6 0.43 10.9 1.1 2.4 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0197) DUF974 PF06159.8 CCU98401.1 - 3.7e-08 33.1 0.0 7.7e-06 25.5 0.0 3.0 1 1 0 1 1 1 1 Protein of unknown function (DUF974) DUF2454 PF10521.4 CCU98402.1 - 2.7e-08 33.1 0.0 4.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) zf-C3HC4_3 PF13920.1 CCU98403.1 - 3.6e-05 23.3 9.0 3.6e-05 23.3 6.2 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 CCU98403.1 - 1 9.8 30.2 0.99 9.8 1.7 6.3 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C3HC4 PF00097.20 CCU98403.1 - 8.5 6.1 25.9 0.18 11.4 6.4 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPF0020 PF01170.13 CCU98404.1 - 8.2e-07 28.7 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CCU98404.1 - 0.0035 17.3 1.0 0.0078 16.2 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CCU98404.1 - 0.042 13.3 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 DNA methylase DNA_ligase_A_M PF01068.16 CCU98405.1 - 6.1e-10 38.8 0.0 8.9e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 CCU98405.1 - 0.007 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain mRNA_cap_enzyme PF01331.14 CCU98405.1 - 0.22 11.1 0.0 0.45 10.1 0.0 1.5 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain Mito_carr PF00153.22 CCU98406.1 - 0.00017 21.2 1.6 0.051 13.2 0.1 3.2 3 0 0 3 3 3 2 Mitochondrial carrier protein V-ATPase_H_N PF03224.9 CCU98407.1 - 2.4e-50 171.4 0.0 1.9e-49 168.4 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 CCU98407.1 - 3.2e-31 107.7 0.0 6.7e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 V-ATPase subunit H HEAT_2 PF13646.1 CCU98407.1 - 0.0022 18.2 5.8 0.11 12.8 0.3 3.2 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 CCU98407.1 - 0.029 14.4 2.2 1.6 8.9 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Alkyl_sulf_dimr PF14863.1 CCU98407.1 - 0.18 12.0 1.2 0.57 10.3 0.0 2.4 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation Arm PF00514.18 CCU98407.1 - 0.25 11.2 8.5 16 5.5 0.1 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat MRP-L46 PF11788.3 CCU98408.1 - 7.5e-15 55.5 0.3 1.3e-14 54.7 0.2 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 CBS PF00571.23 CCU98409.1 - 8.6e-18 63.8 2.9 8.1e-05 22.3 0.0 5.3 4 1 0 4 4 4 3 CBS domain Ubiq_cyt_C_chap PF03981.7 CCU98410.1 - 2.7e-29 101.8 0.0 1.1e-28 99.8 0.0 1.8 1 1 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DUF2384 PF09722.5 CCU98410.1 - 0.081 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) His_biosynth PF00977.16 CCU98411.1 - 1.4e-27 96.4 0.0 1.8e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 CCU98411.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Nic96 PF04097.9 CCU98412.1 - 1.2e-157 525.7 0.0 1.8e-157 525.1 0.0 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Pkinase PF00069.20 CCU98413.1 - 1.4e-41 142.3 0.5 1.2e-23 83.6 0.3 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98413.1 - 8.7e-12 44.6 0.5 6e-09 35.3 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CCU98413.1 - 0.13 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glucosamine_iso PF01182.15 CCU98414.1 - 1.5e-54 184.7 0.0 1.8e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase tRNA-synt_2b PF00587.20 CCU98415.1 - 3.1e-42 144.0 0.0 5e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCU98415.1 - 1.2e-07 31.5 0.0 4.5e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Anticodon binding domain tRNA-synt_His PF13393.1 CCU98415.1 - 0.066 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Nse4_C PF08743.5 CCU98416.1 - 1.2e-14 54.1 0.0 2.9e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 CCU98416.1 - 8.9e-13 47.8 1.4 1e-12 47.6 0.2 1.7 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE HpaP PF09483.5 CCU98416.1 - 0.027 14.4 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Arf PF00025.16 CCU98417.1 - 1.1e-72 242.9 0.0 1.3e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCU98417.1 - 6.5e-13 48.3 0.0 6.9e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CCU98417.1 - 1.1e-12 47.5 0.0 1.4e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCU98417.1 - 6.8e-11 41.4 0.6 2.4e-07 29.7 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCU98417.1 - 5.3e-09 35.5 0.0 6.5e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCU98417.1 - 2.4e-07 31.2 0.0 3.2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCU98417.1 - 4e-06 26.7 0.0 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CCU98417.1 - 0.023 13.7 0.1 0.036 13.1 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Spc7 PF08317.6 CCU98418.1 - 0.0048 15.6 1.1 0.0048 15.6 0.8 4.1 2 1 2 4 4 4 3 Spc7 kinetochore protein Bacillus_HBL PF05791.6 CCU98418.1 - 0.0093 15.3 0.1 0.0093 15.3 0.1 4.8 3 1 1 4 4 4 1 Bacillus haemolytic enterotoxin (HBL) DUF869 PF05911.6 CCU98418.1 - 0.066 11.4 48.6 0.2 9.8 15.1 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 CCU98418.1 - 0.068 12.3 13.0 0.5 9.4 2.2 3.2 3 0 0 3 3 3 0 Reovirus sigma C capsid protein GAS PF13851.1 CCU98418.1 - 2.3 7.3 62.2 0.48 9.6 10.0 4.8 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 CCU98418.1 - 9.1 5.2 63.4 0.52 9.3 14.5 3.6 2 1 2 4 4 4 0 Autophagy protein Apg6 Lon_C PF05362.8 CCU98419.1 - 1.2e-64 217.4 0.0 2e-64 216.6 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CCU98419.1 - 1.9e-23 83.0 0.0 4e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCU98419.1 - 2e-09 37.2 0.0 6.1e-09 35.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 CCU98419.1 - 3.8e-09 36.1 0.0 9.3e-09 34.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_25 PF13481.1 CCU98419.1 - 1.1e-05 24.9 0.1 2.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCU98419.1 - 1.2e-05 25.3 0.3 7.2e-05 22.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CCU98419.1 - 3.5e-05 24.5 0.0 0.00013 22.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCU98419.1 - 6.6e-05 22.5 0.1 0.00022 20.9 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CCU98419.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCU98419.1 - 0.00033 20.8 0.0 0.005 16.9 0.0 2.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CCU98419.1 - 0.0033 16.6 0.1 0.025 13.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CCU98419.1 - 0.0034 16.5 0.0 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 CCU98419.1 - 0.0042 15.8 0.9 0.052 12.2 0.0 2.4 3 0 0 3 3 3 1 TIP49 C-terminus AAA_28 PF13521.1 CCU98419.1 - 0.0058 16.5 0.1 0.089 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCU98419.1 - 0.006 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCU98419.1 - 0.0092 15.0 0.0 0.19 10.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CCU98419.1 - 0.0095 15.8 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_30 PF13604.1 CCU98419.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CCU98419.1 - 0.014 15.0 0.0 0.049 13.2 0.0 2.0 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CCU98419.1 - 0.017 14.5 0.0 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.11 CCU98419.1 - 0.019 14.1 0.0 0.078 12.2 0.0 2.0 3 0 0 3 3 2 0 PhoH-like protein Sigma54_activat PF00158.21 CCU98419.1 - 0.021 14.3 0.0 0.097 12.1 0.0 2.0 2 1 1 3 3 3 0 Sigma-54 interaction domain AAA_PrkA PF08298.6 CCU98419.1 - 0.031 12.9 0.1 0.7 8.5 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain Viral_helicase1 PF01443.13 CCU98419.1 - 0.038 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MobB PF03205.9 CCU98419.1 - 0.041 13.5 0.0 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CCU98419.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CCDC-167 PF15188.1 CCU98419.1 - 0.052 13.4 0.5 0.15 11.9 0.3 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 KTI12 PF08433.5 CCU98419.1 - 0.059 12.5 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 CCU98419.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CCU98419.1 - 0.065 13.5 0.1 0.32 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 CCU98419.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein SKI PF01202.17 CCU98419.1 - 0.074 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase UPF0079 PF02367.12 CCU98419.1 - 0.078 12.6 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CCU98419.1 - 0.096 12.3 0.0 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 CCU98419.1 - 0.098 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCU98419.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.10 CCU98419.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 CCU98419.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 CCU98419.1 - 0.17 10.7 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 tRNA-synt_1c PF00749.16 CCU98420.1 - 2.4e-22 79.0 0.0 2.5e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c PF00749.16 CCU98421.1 - 9.3e-35 119.7 0.0 1.5e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain eIF-5_eIF-2B PF01873.12 CCU98422.1 - 3.4e-42 143.0 0.0 4.9e-42 142.5 0.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CCU98422.1 - 1.6e-24 85.6 0.1 1.6e-24 85.6 0.1 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DNA_RNApol_7kD PF03604.8 CCU98422.1 - 0.3 10.6 2.4 0.58 9.6 1.7 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Pkinase PF00069.20 CCU98423.1 - 4.9e-44 150.4 0.0 7.5e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 CCU98423.1 - 2.3e-41 140.6 0.1 5.3e-41 139.4 0.1 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 CCU98423.1 - 2.7e-25 88.9 0.0 4.3e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Epimerase PF01370.16 CCU98423.1 - 6.9e-14 51.8 0.0 1.5e-13 50.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCU98423.1 - 2.6e-09 36.3 0.0 1.6e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 CCU98423.1 - 7.7e-09 34.6 0.0 6.1e-08 31.7 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family APH PF01636.18 CCU98423.1 - 0.00084 19.1 1.0 0.0055 16.4 0.1 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family NmrA PF05368.8 CCU98423.1 - 0.0023 17.2 0.0 0.043 13.0 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family Kinase-like PF14531.1 CCU98423.1 - 0.0044 16.0 0.0 0.0079 15.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PQQ_2 PF13360.1 CCU98423.1 - 0.0048 16.3 0.0 0.083 12.3 0.0 2.6 1 1 0 1 1 1 1 PQQ-like domain YrbL-PhoP_reg PF10707.4 CCU98423.1 - 0.0083 15.4 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 CCU98423.1 - 0.0098 14.9 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ PF01011.16 CCU98423.1 - 0.05 13.1 0.0 0.2 11.2 0.0 2.1 1 0 0 1 1 1 0 PQQ enzyme repeat ArsA_ATPase PF02374.10 CCU98424.1 - 3.7e-106 354.5 0.0 4.3e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CCU98424.1 - 2.2e-14 53.3 0.1 5.2e-14 52.0 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CCU98424.1 - 2.8e-08 33.8 0.0 7.8e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CCU98424.1 - 1.1e-05 24.7 0.3 0.00013 21.2 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 CCU98424.1 - 0.00021 20.8 0.0 0.00094 18.6 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 CCU98424.1 - 0.0038 16.6 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 YhjQ protein MipZ PF09140.6 CCU98424.1 - 0.004 16.2 0.1 0.023 13.7 0.0 2.1 2 1 0 2 2 2 1 ATPase MipZ PhoH PF02562.11 CCU98424.1 - 0.0083 15.3 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.1 CCU98424.1 - 0.0098 15.3 0.1 0.06 12.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain CTP_synth_N PF06418.9 CCU98424.1 - 0.056 12.5 0.1 7.3 5.6 0.0 2.2 2 0 0 2 2 2 0 CTP synthase N-terminus AAA_24 PF13479.1 CCU98424.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCU98424.1 - 0.091 12.5 0.1 0.94 9.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain NB-ARC PF00931.17 CCU98424.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Acetyltransf_1 PF00583.19 CCU98425.1 - 2.6e-13 49.8 0.1 3.8e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCU98425.1 - 2.4e-05 24.0 0.0 4.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CCU98425.1 - 5.8e-05 23.1 0.0 0.00012 22.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCU98425.1 - 0.0039 17.0 0.1 0.005 16.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCU98425.1 - 0.0049 16.7 0.7 0.012 15.4 0.5 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCU98425.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PTPS PF01242.14 CCU98425.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Atg14 PF10186.4 CCU98426.1 - 9.7e-10 37.8 7.2 2.4e-09 36.5 5.0 1.7 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF3618 PF12277.3 CCU98426.1 - 0.042 13.8 7.7 0.26 11.3 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3618) DUF883 PF05957.8 CCU98426.1 - 0.17 12.2 3.7 2.4 8.6 2.5 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) CDC45 PF02724.9 CCU98427.1 - 3.1e-187 623.4 0.0 3.6e-187 623.2 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF1509 PF07420.6 CCU98427.1 - 0.43 9.7 5.5 0.69 9.1 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) SNF2_N PF00176.18 CCU98428.1 - 5.4e-84 281.4 0.7 9.4e-84 280.7 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.20 CCU98428.1 - 1.3e-19 69.9 0.1 3.5e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 CCU98428.1 - 9e-19 67.1 0.7 1.7e-17 63.0 0.0 3.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.8 CCU98428.1 - 4.7e-14 51.9 6.9 4.7e-14 51.9 4.8 2.9 3 0 0 3 3 3 1 HSA SnAC PF14619.1 CCU98428.1 - 5.1e-14 52.1 2.2 5.1e-14 52.1 1.5 4.2 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Usp PF00582.21 CCU98429.1 - 2.2e-20 73.2 0.0 3.3e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Toprim_4 PF13662.1 CCU98429.1 - 0.095 12.7 0.0 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 Toprim domain Ribosomal_L3 PF00297.17 CCU98430.1 - 4.1e-120 400.0 7.4 4.9e-120 399.8 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 RRM_1 PF00076.17 CCU98431.1 - 1e-34 117.9 0.0 2.2e-18 65.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU98431.1 - 2.8e-22 78.4 0.0 8.1e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU98431.1 - 7.6e-18 64.1 0.0 7.2e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCU98431.1 - 0.0029 17.3 0.0 0.78 9.5 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 Per1 PF04080.8 CCU98432.1 - 3e-84 282.6 1.5 5.2e-84 281.8 1.0 1.4 1 0 0 1 1 1 1 Per1-like eIF3_subunit PF08597.5 CCU98433.1 - 8.4e-35 120.4 17.1 9.5e-35 120.3 11.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Troponin-I_N PF11636.3 CCU98433.1 - 2.8 7.7 11.6 3.9 7.2 4.3 2.6 2 0 0 2 2 2 0 Troponin I residues 1-32 tRNA-synt_1 PF00133.17 CCU98434.1 - 2.9e-143 478.0 0.0 3.8e-143 477.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CCU98434.1 - 2.3e-20 72.6 0.0 1.8e-12 46.6 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CCU98434.1 - 3.4e-19 69.1 0.0 6.5e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 CCU98434.1 - 0.0019 17.7 4.3 0.0039 16.7 3.0 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 CCU98434.1 - 0.027 13.5 0.0 2.6 7.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 CCU98434.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Pox_MCEL PF03291.11 CCU98435.1 - 3.4e-66 223.4 0.0 4.2e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_11 PF08241.7 CCU98435.1 - 6.6e-09 36.1 0.0 1.5e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCU98435.1 - 7.2e-09 35.5 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCU98435.1 - 2.6e-08 34.4 0.0 5.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCU98435.1 - 3.2e-08 33.9 0.0 7.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCU98435.1 - 1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCU98435.1 - 1.8e-05 24.9 0.0 4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCU98435.1 - 0.00034 20.0 0.0 0.00068 19.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 CCU98435.1 - 0.01 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 CCU98435.1 - 0.061 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Mak10 PF04112.8 CCU98436.1 - 2.9e-27 94.9 0.0 4.2e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase PIG-U PF06728.8 CCU98437.1 - 7.6e-81 271.8 21.1 8.7e-81 271.6 14.6 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mo25 PF08569.6 CCU98438.1 - 7.8e-75 251.9 8.3 4.2e-72 243.0 5.7 2.9 1 1 0 1 1 1 1 Mo25-like V-ATPase_H_N PF03224.9 CCU98438.1 - 8.6e-06 25.0 2.9 1.5e-05 24.2 2.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H HEAT_2 PF13646.1 CCU98438.1 - 0.00079 19.6 0.2 0.11 12.7 0.0 2.3 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 CCU98438.1 - 0.015 15.8 0.4 24 5.5 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat RIX1 PF08167.7 CCU98438.1 - 0.026 14.1 0.0 1.2 8.7 0.0 2.3 1 1 1 2 2 2 0 rRNA processing/ribosome biogenesis DUF3361 PF11841.3 CCU98438.1 - 0.078 12.6 0.4 0.2 11.3 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3361) Adaptin_N PF01602.15 CCU98439.1 - 1.1e-134 449.6 4.0 1.3e-134 449.4 2.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CCU98439.1 - 9.6e-15 54.9 0.0 1.7e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 CCU98439.1 - 2e-06 27.9 3.9 0.41 10.9 0.0 4.9 3 2 0 3 3 3 2 HEAT repeats HEAT PF02985.17 CCU98439.1 - 2.4e-06 27.1 1.7 17 5.8 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 CCU98439.1 - 0.0037 17.1 3.2 0.16 11.8 0.3 3.2 2 2 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 CCU98439.1 - 0.023 14.3 4.4 0.045 13.3 0.1 3.3 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) UPF1_Zn_bind PF09416.5 CCU98440.1 - 5e-63 211.2 1.7 1.2e-62 210.0 1.2 1.6 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 CCU98440.1 - 2.1e-58 197.0 0.0 5.4e-58 195.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CCU98440.1 - 3.4e-54 183.9 0.6 5.7e-54 183.1 0.4 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCU98440.1 - 3.9e-14 52.7 0.2 8.3e-13 48.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCU98440.1 - 9.2e-13 47.7 0.5 2.8e-12 46.1 0.4 1.8 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 CCU98440.1 - 1.6e-06 28.1 0.0 3.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 CCU98440.1 - 5.1e-05 22.7 0.1 0.029 13.6 0.1 2.4 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 CCU98440.1 - 6.1e-05 22.7 0.1 0.00022 20.9 0.1 2.0 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 CCU98440.1 - 0.0003 20.4 0.0 1.3 8.4 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 CCU98440.1 - 0.00084 18.4 0.1 0.00084 18.4 0.1 3.8 4 1 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 CCU98440.1 - 0.0012 18.3 0.5 0.003 17.0 0.3 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.17 CCU98440.1 - 0.0046 16.4 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KaiC PF06745.8 CCU98440.1 - 0.007 15.5 0.0 0.37 9.8 0.0 2.2 2 0 0 2 2 2 1 KaiC SNF2_N PF00176.18 CCU98440.1 - 0.0077 15.0 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain PhoH PF02562.11 CCU98440.1 - 0.014 14.6 0.1 0.081 12.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein PIF1 PF05970.9 CCU98440.1 - 0.028 13.3 0.1 4.2 6.2 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_5 PF07728.9 CCU98440.1 - 0.03 14.0 0.2 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCU98440.1 - 0.069 13.2 0.0 0.27 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCU98440.1 - 0.076 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCU98440.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Big_3_3 PF13750.1 CCU98440.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) AMP-binding PF00501.23 CCU98441.1 - 6.2e-86 288.3 0.0 7.8e-86 288.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCU98441.1 - 1e-10 42.4 0.1 6.4e-10 39.8 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF500 PF04366.7 CCU98443.1 - 1.1e-32 112.1 0.1 1.7e-32 111.5 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CCU98443.1 - 3.7e-11 42.2 0.0 6.5e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCU98443.1 - 4.3e-08 32.5 0.0 7.5e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CCU98443.1 - 2.3e-07 30.2 0.0 4.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.20 CCU98444.1 - 1e-55 188.7 0.0 3e-40 138.0 0.0 3.3 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98444.1 - 9.5e-29 100.2 0.1 1.1e-18 67.2 0.0 3.3 4 0 0 4 4 4 2 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 CCU98444.1 - 3.5e-18 65.7 2.5 1.5e-16 60.4 0.0 3.0 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.1 CCU98444.1 - 4e-12 45.8 0.0 8.4e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.17 CCU98444.1 - 1.2e-10 41.3 0.1 2.9e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 RWD domain APH PF01636.18 CCU98444.1 - 0.0013 18.5 0.2 0.0013 18.5 0.2 4.1 5 1 0 5 5 5 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCU98444.1 - 0.0036 16.3 0.0 0.01 14.8 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Ank_4 PF13637.1 CCU98445.1 - 1.9e-11 44.1 0.0 5.1e-10 39.5 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCU98445.1 - 3.9e-10 39.9 0.0 9.1e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCU98445.1 - 3.8e-08 33.3 0.2 1.4e-07 31.5 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CCU98445.1 - 8.8e-07 28.4 0.0 2.3e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 CCU98445.1 - 1.2e-05 25.0 0.1 0.0011 18.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat SUKH_6 PF14568.1 CCU98445.1 - 0.095 13.1 0.1 0.39 11.2 0.0 2.0 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall Nucleoporin_FG PF13634.1 CCU98446.1 - 2.7e-16 59.8 116.7 2.2e-09 37.5 33.8 3.3 1 1 2 3 3 3 3 Nucleoporin FG repeat region Apc4 PF12896.2 CCU98446.1 - 0.013 14.7 0.1 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 AvrPto PF11592.3 CCU98446.1 - 0.045 13.5 0.4 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto Mnd1 PF03962.10 CCU98446.1 - 0.099 12.3 8.2 0.11 12.1 2.2 2.4 1 1 2 3 3 3 0 Mnd1 family Rab5-bind PF09311.6 CCU98446.1 - 0.31 10.9 7.1 0.69 9.7 4.9 1.7 1 1 0 1 1 1 0 Rabaptin-like protein DUF3571 PF12095.3 CCU98446.1 - 0.49 10.6 2.7 13 6.1 0.1 3.0 2 2 0 3 3 3 0 Protein of unknown function (DUF3571) ABC_tran PF00005.22 CCU98447.1 - 4.1e-29 101.6 0.0 6.4e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CCU98447.1 - 6.7e-13 48.6 5.0 8.9e-13 48.2 3.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 CCU98447.1 - 0.00031 20.0 0.2 0.0034 16.6 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CCU98447.1 - 0.031 13.4 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCU98447.1 - 0.086 12.3 1.7 0.16 11.5 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.1 CCU98447.1 - 0.13 13.1 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 CCU98447.1 - 0.13 10.8 0.0 0.22 10.0 0.0 1.4 1 1 0 1 1 1 0 Predicted ATPase of the ABC class AAA_16 PF13191.1 CCU98447.1 - 0.15 12.0 1.0 1.2 9.0 0.7 2.2 1 1 0 1 1 1 0 AAA ATPase domain OGG_N PF07934.7 CCU98448.1 - 3.1e-22 78.7 0.1 5.1e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CCU98448.1 - 1.4e-09 38.2 0.0 2.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CCU98448.1 - 0.00057 19.4 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 CCU98448.1 - 0.18 11.9 0.1 0.71 10.0 0.1 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix domain GLE1 PF07817.8 CCU98449.1 - 2.4e-24 85.6 0.1 2.4e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 GLE1-like protein DUF4551 PF15087.1 CCU98449.1 - 0.011 14.1 7.4 0.0072 14.7 4.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4629 PF15442.1 CCU98449.1 - 0.27 11.3 11.1 0.53 10.4 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) AAA_23 PF13476.1 CCU98449.1 - 2.8 8.2 11.0 4.8 7.4 7.6 1.4 1 0 0 1 1 1 0 AAA domain Gly-zipper_OmpA PF13436.1 CCU98450.1 - 1.2 8.7 14.2 4.5 6.9 0.4 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain TRAPP PF04051.11 CCU98451.1 - 0.13 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component TRAPP PF04051.11 CCU98452.1 - 9.3e-10 38.2 0.0 1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Aldedh PF00171.17 CCU98453.1 - 1.1e-103 347.0 0.0 1.3e-103 346.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GOLD_2 PF13897.1 CCU98454.1 - 3.7 7.7 5.6 0.85 9.8 0.1 2.7 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking NOGCT PF08155.6 CCU98455.1 - 2e-29 101.0 2.8 5.6e-29 99.5 1.9 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 CCU98455.1 - 3.8e-29 100.3 0.2 7.7e-29 99.3 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 CCU98455.1 - 8.2e-18 64.4 0.0 2e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCU98455.1 - 3.4e-09 36.1 0.0 5.8e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CCU98455.1 - 2.6e-05 24.6 0.0 7.8e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 CCU98455.1 - 0.00036 20.3 2.9 0.44 10.3 0.0 3.4 2 1 1 3 3 3 2 Dynamin family Ras PF00071.17 CCU98455.1 - 0.0021 17.4 0.0 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 Ras family AIG1 PF04548.11 CCU98455.1 - 0.0076 15.3 1.4 0.021 13.9 0.0 2.3 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 CCU98455.1 - 0.0088 15.2 0.0 0.078 12.1 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCU98455.1 - 0.25 11.3 2.7 2.1 8.2 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain GTP_EFTU PF00009.22 CCU98455.1 - 0.56 9.6 6.2 0.15 11.4 0.2 3.0 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Gas_vesicle_C PF01304.12 CCU98455.1 - 2 8.0 8.9 11 5.8 6.1 2.3 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain Sugar_tr PF00083.19 CCU98456.1 - 3.7e-159 530.0 57.5 1.8e-83 280.6 17.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCU98456.1 - 2.3e-29 102.1 74.0 5.6e-17 61.4 22.3 3.9 3 2 1 4 4 4 3 Major Facilitator Superfamily Transport_MerF PF11431.3 CCU98456.1 - 0.27 10.9 7.1 3.3 7.4 0.5 2.8 2 0 0 2 2 2 0 Membrane transport protein MerF DUF1843 PF08898.5 CCU98456.1 - 0.31 11.0 0.9 41 4.3 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) ChaC PF04752.7 CCU98458.1 - 9.5e-30 103.8 0.0 1.7e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 ChaC-like protein DUF1749 PF08538.5 CCU98458.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 CCU98458.1 - 0.0068 16.1 0.0 0.024 14.3 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCU98458.1 - 0.042 13.4 0.0 0.68 9.4 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCU98459.1 - 0.00027 20.7 0.0 0.00087 19.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCU98459.1 - 0.00062 19.7 0.2 0.0014 18.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.4 CCU98459.1 - 0.021 13.5 0.1 0.046 12.4 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta-hydrolase family Lipase_3 PF01764.20 CCU98459.1 - 0.063 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF1749 PF08538.5 CCU98459.1 - 0.087 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.2 CCU98459.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.8 CCU98459.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein CRAL_TRIO PF00650.15 CCU98460.1 - 2.3e-34 118.2 0.1 4e-34 117.4 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCU98460.1 - 6.3e-09 35.8 0.2 2e-08 34.2 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CCU98460.1 - 0.0055 16.6 0.1 0.017 14.9 0.1 1.7 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Aldedh PF00171.17 CCU98461.1 - 7.8e-149 495.9 0.7 9.7e-149 495.6 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CCU98461.1 - 0.078 12.1 0.0 0.36 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) RNase_H PF00075.19 CCU98462.1 - 0.063 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 RNase H GATA PF00320.22 CCU98462.1 - 0.14 11.5 0.1 0.43 9.9 0.1 1.8 1 0 0 1 1 1 0 GATA zinc finger CHCH PF06747.8 CCU98463.1 - 0.042 13.7 4.6 0.3 11.0 0.1 2.3 2 0 0 2 2 2 0 CHCH domain ChaC PF04752.7 CCU98464.1 - 7.9e-50 169.2 0.0 1.5e-49 168.3 0.0 1.5 1 0 0 1 1 1 1 ChaC-like protein DnaJ PF00226.26 CCU98464.1 - 1.5e-25 88.6 1.7 6.2e-25 86.7 1.2 2.1 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 CCU98464.1 - 1.5e-09 37.7 2.3 1.5e-09 37.7 1.6 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCU98464.1 - 4e-08 33.1 1.2 4e-08 33.1 0.8 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCU98464.1 - 1e-05 25.5 2.5 0.03 14.4 0.1 3.2 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CCU98464.1 - 0.012 15.9 8.1 0.59 10.5 1.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCU98464.1 - 0.029 14.2 6.2 0.38 10.7 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCU98464.1 - 0.16 12.3 7.2 0.65 10.4 1.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type PhoD PF09423.5 CCU98465.1 - 9.4e-05 21.1 0.0 0.048 12.2 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Pectate_lyase_3 PF12708.2 CCU98466.1 - 1.9e-27 96.8 1.3 1.7e-15 57.7 0.2 2.4 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 CCU98466.1 - 0.018 14.5 0.1 0.059 12.8 0.0 1.9 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Cyt-b5 PF00173.23 CCU98467.1 - 1.3e-17 63.3 0.0 2.1e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arginase PF00491.16 CCU98468.1 - 5.4e-76 255.5 0.0 7.1e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family AAA PF00004.24 CCU98469.1 - 6.7e-92 304.6 0.0 8.1e-47 158.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCU98469.1 - 8e-13 47.9 0.0 1.3e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCU98469.1 - 1.1e-11 45.0 0.9 9.6e-05 22.4 0.5 3.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 CCU98469.1 - 2.2e-11 43.9 0.0 0.00015 21.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCU98469.1 - 9e-11 42.0 0.6 0.0022 18.1 0.0 4.8 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 CCU98469.1 - 1.8e-10 41.6 0.0 4.8e-05 24.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CCU98469.1 - 8.1e-10 38.5 0.4 0.0018 18.0 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CCU98469.1 - 3.9e-09 36.5 0.0 0.0026 17.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CCU98469.1 - 9.9e-09 34.3 0.0 0.00029 19.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 CCU98469.1 - 1.3e-07 31.5 0.0 0.0024 17.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 CCU98469.1 - 2.1e-07 30.3 0.2 0.022 13.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CCU98469.1 - 2.6e-07 30.2 0.8 0.017 14.8 0.0 3.8 3 0 0 3 3 3 2 Part of AAA domain RNA_helicase PF00910.17 CCU98469.1 - 5.7e-07 29.6 0.0 0.055 13.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 CCU98469.1 - 6.3e-07 28.9 0.5 0.0089 15.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 CCU98469.1 - 6.3e-07 28.6 0.0 0.0035 16.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.1 CCU98469.1 - 6.9e-07 29.3 0.0 0.019 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CCU98469.1 - 4.8e-06 26.1 10.8 0.17 11.2 0.1 5.0 3 2 1 5 5 5 2 AAA domain NACHT PF05729.7 CCU98469.1 - 6.7e-06 25.8 0.4 0.48 10.0 0.0 3.5 2 1 1 3 3 3 2 NACHT domain AAA_3 PF07726.6 CCU98469.1 - 1.1e-05 25.1 0.0 0.042 13.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CCU98469.1 - 1.5e-05 25.3 0.0 0.026 14.8 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.1 CCU98469.1 - 1.7e-05 25.1 0.0 0.21 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 CCU98469.1 - 2e-05 24.6 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 CCU98469.1 - 4.9e-05 23.3 0.0 0.01 15.7 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 CCU98469.1 - 0.0002 21.2 0.1 0.83 9.5 0.0 2.5 2 0 0 2 2 2 2 Shikimate kinase KaiC PF06745.8 CCU98469.1 - 0.00035 19.7 0.1 1.2 8.2 0.0 3.2 3 0 0 3 3 3 1 KaiC Viral_helicase1 PF01443.13 CCU98469.1 - 0.00062 19.3 0.0 0.59 9.6 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 CCU98469.1 - 0.00074 19.0 0.1 0.29 10.6 0.0 3.4 3 1 0 3 3 3 1 Sigma-54 interaction domain ATP-synt_ab PF00006.20 CCU98469.1 - 0.00075 19.0 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Parvo_NS1 PF01057.12 CCU98469.1 - 0.0012 17.8 0.1 1.3 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Rad17 PF03215.10 CCU98469.1 - 0.0012 17.6 0.0 0.39 9.3 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein PhoH PF02562.11 CCU98469.1 - 0.0019 17.4 0.3 0.77 8.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein NB-ARC PF00931.17 CCU98469.1 - 0.0026 16.6 0.1 0.27 10.0 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.8 CCU98469.1 - 0.0043 16.0 0.0 0.013 14.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Trypan_PARP PF05887.6 CCU98469.1 - 0.0051 16.6 15.1 0.011 15.5 10.5 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) ResIII PF04851.10 CCU98469.1 - 0.0066 16.2 0.0 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 CCU98469.1 - 0.014 14.9 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 CCU98469.1 - 0.03 13.1 0.0 6.2 5.5 0.0 2.5 2 0 0 2 2 2 0 AFG1-like ATPase Arch_ATPase PF01637.13 CCU98469.1 - 0.031 13.9 0.1 1.1 8.8 0.0 3.0 2 2 2 4 4 4 0 Archaeal ATPase AAA_24 PF13479.1 CCU98469.1 - 0.04 13.5 0.2 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CCU98469.1 - 0.054 13.1 0.1 4.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 CCU98469.1 - 0.14 11.8 0.2 3.6 7.2 0.0 2.9 3 1 1 4 4 2 0 NTPase SRPRB PF09439.5 CCU98469.1 - 0.19 10.9 0.0 6.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CCU98469.1 - 0.23 10.9 0.0 7.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.4 CCU98469.1 - 0.24 10.3 0.2 21 3.9 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 CCU98469.1 - 0.33 11.2 0.0 6.9 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain P21-Arc PF04062.9 CCU98470.1 - 1.1e-61 207.5 0.0 1.7e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit PCI PF01399.22 CCU98471.1 - 2.4e-13 50.3 0.2 1e-12 48.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain HTH_20 PF12840.2 CCU98471.1 - 0.4 10.5 3.0 0.63 9.8 0.1 2.9 2 2 0 2 2 2 0 Helix-turn-helix domain Sybindin PF04099.7 CCU98472.1 - 4.4e-37 126.9 0.0 4.9e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CCU98472.1 - 2.5e-07 30.6 0.0 2.6e-07 30.5 0.0 1.2 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region 2-Hacid_dh_C PF02826.14 CCU98474.1 - 3.8e-48 162.9 0.0 5.6e-48 162.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCU98474.1 - 1.9e-14 53.2 0.0 2.5e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCU98474.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 CCU98474.1 - 0.1 12.0 0.2 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NIF PF03031.13 CCU98475.1 - 4.6e-33 114.1 0.0 7.8e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2767 PF10965.3 CCU98475.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) Methyltransf_16 PF10294.4 CCU98476.1 - 2.1e-12 46.8 0.0 3.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCU98476.1 - 6.2e-05 23.5 0.0 0.0001 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCU98476.1 - 0.0039 16.5 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CCU98476.1 - 0.0058 17.0 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 CCU98476.1 - 0.082 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 GidB PF02527.10 CCU98476.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.1 CCU98476.1 - 0.15 11.6 0.0 0.53 9.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MRP-S28 PF10213.4 CCU98477.1 - 5.1e-23 81.5 0.0 1.1e-22 80.5 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein RRP7 PF12923.2 CCU98478.1 - 4.9e-23 81.5 3.3 8.6e-22 77.5 3.0 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 CCU98478.1 - 0.00011 21.6 0.0 0.00066 19.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU98478.1 - 0.044 13.7 0.0 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Trypan_PARP PF05887.6 CCU98478.1 - 0.78 9.5 9.6 0.72 9.6 0.3 2.9 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) MCM PF00493.18 CCU98479.1 - 4.4e-136 453.0 0.2 6.3e-136 452.5 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCU98479.1 - 4.7e-18 65.8 0.0 1.2e-17 64.4 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCU98479.1 - 1.1e-07 31.1 0.0 9.8e-07 28.1 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCU98479.1 - 0.0015 17.9 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 CCU98479.1 - 0.0017 17.9 0.0 0.0042 16.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCU98479.1 - 0.034 13.8 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tir_receptor_M PF03549.9 CCU98479.1 - 0.06 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain Proteasome PF00227.21 CCU98481.1 - 5.3e-46 156.2 0.0 8.4e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M28 PF04389.12 CCU98481.1 - 1.2e-19 70.7 0.0 2.1e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CCU98481.1 - 4e-09 36.0 0.1 1.2e-08 34.4 0.1 1.8 2 0 0 2 2 2 1 PA domain Proteasome_A_N PF10584.4 CCU98481.1 - 0.00033 19.9 0.3 0.00065 18.9 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2554 PF10829.3 CCU98481.1 - 0.15 12.2 0.1 0.48 10.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2554) WD40 PF00400.27 CCU98482.1 - 4e-49 162.8 12.4 6.5e-10 38.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CCU98482.1 - 9.1e-05 20.7 0.7 2.9 5.9 0.1 3.9 2 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CCU98482.1 - 0.0036 16.8 0.5 1.9 7.9 0.1 2.5 2 1 0 2 2 2 2 PQQ-like domain DUF2780 PF11075.3 CCU98482.1 - 0.16 12.0 4.6 0.15 12.0 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) tRNA-synt_2 PF00152.15 CCU98484.1 - 1.5e-85 286.9 0.0 2.3e-85 286.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCU98484.1 - 3.2e-10 39.7 0.0 5.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CCU98484.1 - 0.0067 16.0 0.0 0.24 10.9 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) T2SE_Nter PF05157.10 CCU98484.1 - 0.038 14.0 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain cNMP_binding PF00027.24 CCU98485.1 - 1.1e-39 134.0 0.0 1e-20 73.3 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Mt_ATP-synt_D PF05873.7 CCU98485.1 - 4.9e-10 39.2 0.5 8.2e-10 38.5 0.3 1.3 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Prominin PF05478.6 CCU98485.1 - 0.077 10.5 1.1 0.1 10.1 0.8 1.1 1 0 0 1 1 1 0 Prominin AcetDehyd-dimer PF09290.6 CCU98485.1 - 0.086 12.7 0.5 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Ribosomal_S25 PF03297.10 CCU98486.1 - 1.9e-39 133.9 0.3 2e-39 133.8 0.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MerR_1 PF13411.1 CCU98486.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 MerR HTH family regulatory protein EF-hand_6 PF13405.1 CCU98487.1 - 9.5e-16 56.2 0.1 2.3e-05 23.8 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CCU98487.1 - 5.9e-14 51.9 0.0 4.3e-08 33.1 0.0 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CCU98487.1 - 6.6e-14 50.0 0.3 5.4e-05 22.2 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 CCU98487.1 - 5.7e-08 32.5 0.0 0.0082 16.0 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CCU98487.1 - 3.2e-07 29.3 0.7 0.0097 15.2 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CCU98487.1 - 4.1e-06 26.3 0.3 0.045 13.3 0.0 4.3 3 2 2 5 5 5 3 EF-hand domain pair UPF0154 PF03672.8 CCU98487.1 - 0.022 14.3 0.0 0.71 9.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF2267 PF10025.4 CCU98487.1 - 0.046 13.7 0.0 4.3 7.4 0.0 2.2 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) IMD PF08397.6 CCU98488.1 - 0.0098 15.2 2.4 0.015 14.6 1.6 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain Gon7 PF08738.5 CCU98488.1 - 0.013 15.4 1.1 0.028 14.4 0.7 1.5 1 0 0 1 1 1 0 Gon7 family TPR_MLP1_2 PF07926.7 CCU98488.1 - 0.73 9.5 8.7 0.56 9.9 3.7 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein AMMECR1 PF01871.12 CCU98489.1 - 4e-37 126.9 0.0 4.7e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Fork_head PF00250.13 CCU98491.1 - 9.7e-17 60.8 0.0 1.7e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CCU98491.1 - 0.00021 21.3 0.0 0.00053 20.0 0.0 1.7 1 1 0 1 1 1 1 FHA domain Gag_p10 PF02337.12 CCU98491.1 - 0.034 13.8 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral GAG p10 protein DUF788 PF05620.6 CCU98492.1 - 2.5e-35 121.8 0.1 3.2e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF788) SNF5 PF04855.7 CCU98494.1 - 5.9e-52 176.5 0.0 4e-49 167.2 0.0 2.2 2 0 0 2 2 2 2 SNF5 / SMARCB1 / INI1 AT_hook PF02178.14 CCU98494.1 - 0.049 13.3 5.6 0.15 11.7 3.9 1.9 1 0 0 1 1 1 0 AT hook motif Nucleoplasmin PF03066.10 CCU98494.1 - 1.9 7.9 6.2 0.63 9.5 2.2 1.6 2 0 0 2 2 2 0 Nucleoplasmin RRM_1 PF00076.17 CCU98495.1 - 3.7e-27 93.7 0.0 1.4e-16 59.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU98495.1 - 9.1e-18 64.0 0.0 5.1e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU98495.1 - 1.4e-10 40.8 0.0 4.4e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CCU98495.1 - 5.2e-05 22.6 0.9 0.00015 21.1 0.6 1.8 1 0 0 1 1 1 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 CCU98495.1 - 0.0019 17.9 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 CCU98495.1 - 0.009 15.8 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif DUF605 PF04652.11 CCU98495.1 - 1.5 8.1 9.1 1.5 8.1 6.3 1.1 1 0 0 1 1 1 0 Vta1 like Flavokinase PF01687.12 CCU98497.1 - 3.1e-35 120.7 0.0 3.6e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Thr_synth_N PF14821.1 CCU98498.1 - 3.2e-25 87.9 0.0 1.6e-24 85.6 0.0 2.2 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 CCU98498.1 - 4.5e-18 65.5 0.1 1e-17 64.3 0.1 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WD40 PF00400.27 CCU98499.1 - 5.6e-25 86.2 10.3 3.2e-08 33.1 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.1 CCU98499.1 - 0.0073 16.5 10.8 0.14 12.4 0.0 5.1 5 1 0 5 5 5 1 PQQ-like domain DUF3312 PF11768.3 CCU98499.1 - 0.032 12.4 0.0 0.16 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) DUF2415 PF10313.4 CCU98499.1 - 0.091 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) PfkB PF00294.19 CCU98500.1 - 1.3e-39 136.1 0.1 1.5e-39 135.9 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RNA_Me_trans PF04252.8 CCU98501.1 - 1.5e-18 66.9 0.0 1.1e-17 64.0 0.0 2.2 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase SNARE_assoc PF09335.6 CCU98502.1 - 2.1e-11 44.0 8.9 2.1e-11 44.0 6.2 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein Sod_Fe_C PF02777.13 CCU98503.1 - 1.7e-09 37.4 0.0 2.9e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CCU98503.1 - 0.033 14.4 0.0 0.048 13.9 0.0 1.2 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Ndc1_Nup PF09531.5 CCU98504.1 - 2.9e-27 95.3 4.8 8e-18 64.1 1.9 2.2 2 0 0 2 2 2 2 Nucleoporin protein Ndc1-Nup MCM PF00493.18 CCU98505.1 - 8.3e-132 438.9 0.0 3.9e-130 433.4 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 CCU98505.1 - 2.8e-24 85.9 0.0 1.4e-23 83.6 0.0 2.1 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCU98505.1 - 5e-07 29.0 0.1 5.2e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCU98505.1 - 9.6e-07 28.6 0.0 3.2e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 CCU98505.1 - 0.0066 16.8 2.4 0.011 16.0 0.9 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCU98505.1 - 0.0088 15.6 0.0 0.042 13.4 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCU98505.1 - 1.8 8.5 5.6 13 5.7 0.0 3.8 3 2 1 4 4 4 0 AAA ATPase domain LIM PF00412.17 CCU98507.1 - 1.9e-25 88.6 39.0 3.3e-14 52.6 4.7 4.7 4 1 0 4 4 4 3 LIM domain DZR PF12773.2 CCU98507.1 - 0.0069 16.1 22.3 0.18 11.6 2.7 4.3 4 1 0 4 4 4 2 Double zinc ribbon Auto_anti-p27 PF06677.7 CCU98507.1 - 0.26 11.0 5.7 8.2 6.2 0.2 3.9 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) JAB PF01398.16 CCU98508.1 - 7e-16 57.9 0.0 1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CCU98508.1 - 6.8e-07 28.8 0.4 1.7e-06 27.5 0.3 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 CCU98508.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 USP8 dimerisation domain Spc97_Spc98 PF04130.8 CCU98509.1 - 6.6e-107 358.0 0.0 7.9e-107 357.8 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family BatA PF07584.6 CCU98509.1 - 0.0056 16.8 0.7 0.033 14.3 0.7 2.1 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal ADH_N PF08240.7 CCU98510.1 - 1.8e-27 95.2 0.2 3.5e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCU98510.1 - 2.1e-17 62.8 0.3 3.1e-17 62.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCU98510.1 - 4.3e-05 24.4 0.6 8.5e-05 23.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox PF00070.22 CCU98510.1 - 0.05 14.0 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCU98510.1 - 0.16 10.3 0.2 0.24 9.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Ras PF00071.17 CCU98511.1 - 9.7e-34 116.0 0.3 1.2e-33 115.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU98511.1 - 5.7e-11 42.9 0.0 8.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCU98511.1 - 0.00014 21.1 0.0 0.00018 20.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCU98511.1 - 0.00069 19.5 0.0 0.00088 19.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCU98511.1 - 0.0028 17.1 0.0 0.0044 16.4 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Clat_adaptor_s PF01217.15 CCU98512.1 - 1.3e-14 54.0 0.0 5.1e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain RasGAP_C PF03836.10 CCU98513.1 - 3.3e-32 111.1 0.1 3.3e-32 111.1 0.0 2.5 2 1 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 CCU98513.1 - 9.8e-22 77.5 0.0 3e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 CCU98513.1 - 7.2e-16 56.2 26.2 0.12 12.0 0.0 9.6 9 0 0 9 9 9 7 IQ calmodulin-binding motif CH PF00307.26 CCU98513.1 - 1.6e-10 40.9 0.0 3.9e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF2924 PF11149.3 CCU98514.1 - 0.051 13.6 0.4 0.093 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) Abhydrolase_3 PF07859.8 CCU98515.1 - 2.5e-25 89.3 0.4 1.8e-24 86.4 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CCU98515.1 - 2.1e-16 59.5 0.0 5.1e-14 51.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CCU98515.1 - 0.012 15.3 0.0 0.042 13.6 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 CCU98515.1 - 0.013 14.2 0.2 1.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Ytp1 PF10355.4 CCU98516.1 - 5.8e-94 314.2 3.4 8.6e-94 313.7 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CCU98516.1 - 6.2e-09 35.3 0.1 6.2e-09 35.3 0.0 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Aminotran_1_2 PF00155.16 CCU98517.1 - 5.6e-75 252.5 0.0 7.2e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CCU98517.1 - 2.1e-07 30.0 0.0 3.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CCU98517.1 - 0.00023 19.5 0.0 0.00047 18.5 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CCU98517.1 - 0.018 14.1 0.1 0.045 12.8 0.1 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CCU98517.1 - 0.046 12.7 0.1 0.1 11.6 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Tox-HDC PF15656.1 CCU98517.1 - 0.21 11.7 1.1 0.93 9.7 0.1 2.4 2 0 0 2 2 2 0 Toxin with a H, D/N and C signature Ribosomal_S14 PF00253.16 CCU98518.1 - 3e-17 61.7 0.1 4.8e-17 61.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_L19 PF01245.15 CCU98519.1 - 1.1e-23 83.1 0.1 1.9e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 Not3 PF04065.10 CCU98520.1 - 1.1e-92 309.5 19.5 1.5e-92 309.0 13.5 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CCU98520.1 - 2.3e-44 150.4 9.2 8.3e-44 148.7 6.4 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 CCU98520.1 - 0.0019 17.7 2.0 0.0054 16.2 1.4 1.8 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Syntaxin PF00804.20 CCU98520.1 - 0.0037 17.4 1.3 0.0037 17.4 0.9 2.7 1 1 2 3 3 3 1 Syntaxin Exonuc_VII_S PF02609.11 CCU98520.1 - 0.15 11.8 3.6 8.3 6.2 0.2 3.5 3 0 0 3 3 3 0 Exonuclease VII small subunit SART-1 PF03343.8 CCU98523.1 - 2.1e-92 310.4 1.3 4.2e-92 309.4 0.9 1.5 1 1 0 1 1 1 1 SART-1 family Pkinase PF00069.20 CCU98524.1 - 9.7e-62 208.4 0.0 4.6e-61 206.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98524.1 - 1.9e-25 89.3 0.0 6.2e-17 61.5 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCU98524.1 - 5.2e-07 28.9 0.0 0.0014 17.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CCU98524.1 - 0.025 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MCR_beta PF02241.13 CCU98524.1 - 0.13 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain Pkinase PF00069.20 CCU98525.1 - 1.7e-60 204.3 0.0 4.4e-60 203.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98525.1 - 3.6e-42 144.2 0.0 2.2e-41 141.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 CCU98525.1 - 7.8e-36 123.4 0.0 1.3e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.1 CCU98525.1 - 0.011 14.6 0.1 0.14 11.0 0.1 2.3 2 1 0 2 2 2 0 Kinase-like APH PF01636.18 CCU98525.1 - 0.037 13.7 2.2 0.086 12.5 0.2 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Sedlin_N PF04628.8 CCU98526.1 - 1.8e-12 47.2 0.0 2.3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Rho_GDI PF02115.12 CCU98527.1 - 2.8e-45 154.2 0.0 3.8e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Complex1_LYR PF05347.10 CCU98527.1 - 2.3e-08 33.7 4.0 4.1e-08 32.8 2.8 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCU98527.1 - 8.5e-05 22.6 4.0 0.00018 21.6 2.8 1.5 1 0 0 1 1 1 1 Complex1_LYR-like DUF1640 PF07798.6 CCU98528.1 - 2.4e-19 70.0 0.3 3.3e-19 69.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) OmpH PF03938.9 CCU98528.1 - 0.0034 17.3 1.0 0.0056 16.6 0.7 1.4 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Apolipoprotein PF01442.13 CCU98528.1 - 0.0056 16.2 5.0 0.0056 16.2 3.4 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Prominin PF05478.6 CCU98528.1 - 0.025 12.1 0.4 0.033 11.7 0.3 1.1 1 0 0 1 1 1 0 Prominin Fmp27_WPPW PF10359.4 CCU98528.1 - 0.03 12.7 1.6 0.046 12.1 1.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Corona_S2 PF01601.11 CCU98528.1 - 0.042 11.9 0.0 0.057 11.5 0.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Baculo_PEP_C PF04513.7 CCU98528.1 - 0.14 11.9 6.8 0.45 10.3 4.7 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 CCU98528.1 - 0.21 11.7 4.5 0.46 10.6 3.1 1.5 1 0 0 1 1 1 0 Syntaxin DUF4404 PF14357.1 CCU98528.1 - 0.41 11.0 5.6 0.47 10.8 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF2205 PF10224.4 CCU98528.1 - 0.97 9.0 6.1 1.5 8.4 3.7 1.8 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) GTP_EFTU PF00009.22 CCU98529.1 - 1.5e-45 154.9 0.0 2.3e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCU98529.1 - 4.9e-25 87.5 0.3 1.3e-24 86.2 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCU98529.1 - 3.5e-09 36.6 0.7 1.4e-08 34.7 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCU98529.1 - 4.8e-05 23.2 0.0 0.00015 21.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCU98529.1 - 0.065 13.7 0.0 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein CDC27 PF09507.5 CCU98529.1 - 0.78 8.8 12.3 1.2 8.2 8.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DAD PF02109.11 CCU98530.1 - 1.5e-34 118.4 5.2 5.6e-34 116.5 3.6 1.7 1 1 0 1 1 1 1 DAD family DUF1097 PF06496.6 CCU98530.1 - 0.00032 20.5 1.5 0.00045 20.0 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1097) DUF1768 PF08719.6 CCU98531.1 - 3.8e-22 78.7 0.0 4.8e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Ribosomal_S7e PF01251.13 CCU98532.1 - 8.3e-77 256.9 1.9 9.1e-77 256.8 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e FAD_binding_1 PF00667.15 CCU98533.1 - 1.2e-47 162.2 0.0 1.9e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CCU98533.1 - 1.2e-07 32.2 0.0 3.4e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF3818 PF12825.2 CCU98534.1 - 5.8e-76 255.3 0.0 7.4e-76 255.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CCU98534.1 - 3.3e-07 29.9 0.0 7.4e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 PX-associated S-AdoMet_synt_C PF02773.11 CCU98535.1 - 4e-75 250.1 0.3 4e-75 250.1 0.2 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CCU98535.1 - 3.7e-47 159.1 0.0 6.4e-47 158.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CCU98535.1 - 4.7e-45 151.9 0.1 1e-44 150.8 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Lactamase_B_3 PF13483.1 CCU98535.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain S4 PF01479.20 CCU98536.1 - 3.8e-12 45.4 0.0 6.5e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 CCU98536.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 S4 domain Trypan_PARP PF05887.6 CCU98536.1 - 7.2 6.4 19.7 12 5.6 13.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PTR2 PF00854.16 CCU98537.1 - 1.2e-32 113.0 16.2 1.2e-31 109.8 11.2 2.0 1 1 0 1 1 1 1 POT family Glyco_hydro_cc PF11790.3 CCU98538.1 - 3.4e-57 193.6 11.2 3.8e-57 193.4 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_2_C PF02836.12 CCU98538.1 - 0.00012 21.0 0.4 0.00017 20.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_53 PF07745.8 CCU98538.1 - 0.014 14.1 3.9 0.037 12.8 2.7 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 53 CwfJ_C_1 PF04677.10 CCU98538.1 - 0.12 12.0 0.1 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 WLM PF08325.5 CCU98539.1 - 7.6e-19 68.3 0.0 1.4e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.18 CCU98539.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CCU98539.1 - 0.06 13.6 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Adap_comp_sub PF00928.16 CCU98540.1 - 4.6e-37 127.5 0.0 5.9e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CCU98540.1 - 0.026 14.2 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain zf-Tim10_DDP PF02953.10 CCU98543.1 - 1.3e-19 69.2 2.2 1.5e-19 68.9 1.3 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.5 CCU98543.1 - 0.014 15.3 0.1 0.044 13.8 0.0 1.7 1 1 1 2 2 2 0 Phasin protein DUF1178 PF06676.6 CCU98543.1 - 0.02 15.0 0.1 0.02 15.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Mmp37 PF09139.6 CCU98543.1 - 0.096 11.6 0.0 0.096 11.6 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 eIF-6 PF01912.13 CCU98544.1 - 9.5e-84 279.4 0.4 1.3e-83 278.9 0.1 1.3 2 0 0 2 2 2 1 eIF-6 family Sec7 PF01369.15 CCU98545.1 - 7.2e-66 221.4 0.1 1.8e-65 220.1 0.1 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CCU98545.1 - 7.1e-51 171.9 2.5 2.7e-50 170.0 1.7 2.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CCU98545.1 - 3.9e-28 96.7 3.0 1.5e-26 91.7 0.0 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Methyltransf_8 PF05148.10 CCU98546.1 - 3.2e-49 167.5 0.0 7.9e-24 84.5 0.0 3.0 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_23 PF13489.1 CCU98546.1 - 0.00016 21.4 0.0 0.00034 20.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCU98546.1 - 0.0091 16.4 0.1 0.084 13.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain DUF572 PF04502.8 CCU98546.1 - 1 8.4 4.7 1.6 7.8 3.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) UPF0113 PF03657.8 CCU98547.1 - 1.1e-10 41.4 0.0 1.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Utp14 PF04615.8 CCU98548.1 - 1.4e-114 383.8 48.2 1.4e-114 383.8 33.4 3.9 3 1 0 3 3 3 1 Utp14 protein DUF947 PF06102.7 CCU98548.1 - 2.2e-39 134.9 16.4 2.2e-39 134.9 11.4 3.8 3 1 1 5 5 5 1 Domain of unknown function (DUF947) NifU_N PF01592.11 CCU98550.1 - 1.4e-51 173.6 0.1 2.2e-51 173.0 0.1 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain adh_short_C2 PF13561.1 CCU98551.1 - 6.1e-32 111.2 0.2 8e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCU98551.1 - 3.6e-30 105.0 0.6 5.1e-30 104.5 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCU98551.1 - 1.6e-17 63.7 0.9 2.2e-17 63.3 0.6 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CCU98551.1 - 2.2e-06 27.3 0.2 2.9e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.20 CCU98551.1 - 0.00033 19.9 3.0 0.00048 19.4 2.1 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme F420_oxidored PF03807.12 CCU98551.1 - 0.0022 18.3 0.7 1.2 9.6 0.1 3.3 3 1 1 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 CCU98551.1 - 0.0036 16.9 0.8 0.053 13.1 0.4 2.3 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2280 PF10045.4 CCU98551.1 - 0.0089 15.9 0.3 1.6 8.6 0.1 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2280) 3Beta_HSD PF01073.14 CCU98551.1 - 0.012 14.3 0.7 0.018 13.7 0.5 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCU98551.1 - 0.018 15.0 0.4 0.041 13.8 0.3 1.8 1 1 0 1 1 1 0 NADH(P)-binding Saccharop_dh PF03435.13 CCU98551.1 - 0.047 12.6 0.7 0.074 12.0 0.4 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase YjeF_N PF03853.10 CCU98551.1 - 0.05 13.2 0.7 0.11 12.1 0.3 1.6 1 1 0 1 1 1 0 YjeF-related protein N-terminus TPP_enzyme_C PF02775.16 CCU98551.1 - 0.062 12.8 0.8 0.18 11.3 0.5 1.9 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ribosomal_L11_N PF03946.9 CCU98552.1 - 1.5e-24 85.2 1.4 2.2e-24 84.6 0.2 1.9 2 1 1 3 3 3 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CCU98552.1 - 0.00018 21.6 0.8 0.0027 17.8 0.3 2.3 1 1 1 2 2 2 2 Ribosomal protein L11, RNA binding domain NUC153 PF08159.7 CCU98553.1 - 3.1e-14 52.2 0.2 5.9e-14 51.3 0.2 1.5 1 0 0 1 1 1 1 NUC153 domain Proteasome PF00227.21 CCU98554.1 - 4.1e-58 195.8 0.0 6.5e-58 195.1 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 CCU98554.1 - 2.7e-10 39.3 0.2 7.4e-10 37.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature HAD PF12710.2 CCU98555.1 - 1e-12 48.6 0.0 1.3e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 CCU98555.1 - 1.2e-06 28.0 0.0 6.7e-06 25.6 0.0 1.9 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 CCU98555.1 - 0.0001 22.5 0.1 0.00044 20.5 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 CCU98555.1 - 0.048 12.8 0.0 0.28 10.3 0.0 2.0 2 0 0 2 2 2 0 Putative Phosphatase Aldedh PF00171.17 CCU98556.1 - 1.3e-77 261.1 0.0 1.6e-77 260.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.13 CCU98556.1 - 0.04 14.6 0.0 0.093 13.4 0.0 1.7 1 0 0 1 1 1 0 Fic/DOC family AAA_2 PF07724.9 CCU98557.1 - 6.6e-54 182.3 0.0 4.5e-50 169.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 CCU98557.1 - 3e-27 95.4 0.1 8.2e-15 55.1 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CCU98557.1 - 2.8e-21 75.1 0.1 2e-20 72.4 0.0 2.7 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CCU98557.1 - 2.2e-15 56.5 0.0 2.5e-09 36.9 0.0 3.6 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 CCU98557.1 - 5e-14 51.9 4.4 1.4e-06 28.0 0.1 3.8 3 0 0 3 3 3 2 Clp amino terminal domain AAA_16 PF13191.1 CCU98557.1 - 1.2e-11 44.9 12.6 5.2e-06 26.5 0.0 5.9 4 3 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 CCU98557.1 - 7.2e-10 39.1 0.8 0.011 15.8 0.0 5.1 3 2 1 4 4 4 2 AAA domain Sigma54_activat PF00158.21 CCU98557.1 - 1.8e-07 30.7 0.0 2.3e-05 23.9 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 CCU98557.1 - 2.2e-06 28.4 2.0 0.2 12.4 1.6 3.8 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CCU98557.1 - 9.2e-06 25.1 0.0 0.048 13.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 CCU98557.1 - 1.3e-05 24.3 0.1 0.013 14.6 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.17 CCU98557.1 - 6.4e-05 23.0 0.0 0.3 11.2 0.0 3.4 4 0 0 4 4 3 2 RNA helicase AAA_33 PF13671.1 CCU98557.1 - 8.4e-05 22.4 2.2 0.14 12.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_19 PF13245.1 CCU98557.1 - 9.5e-05 22.0 0.1 0.075 12.7 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 CCU98557.1 - 0.00014 21.0 0.0 0.14 11.3 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CCU98557.1 - 0.00023 21.1 0.1 0.18 11.7 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 CCU98557.1 - 0.00084 19.6 0.7 0.77 10.0 0.0 3.2 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 CCU98557.1 - 0.00097 18.2 0.0 0.3 10.0 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 CCU98557.1 - 0.0011 18.5 0.0 0.46 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CCU98557.1 - 0.0018 17.2 0.0 0.039 12.8 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Torsin PF06309.6 CCU98557.1 - 0.003 17.4 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 1 1 Torsin AAA_25 PF13481.1 CCU98557.1 - 0.0034 16.8 0.7 1 8.6 0.0 3.7 4 1 0 4 4 3 1 AAA domain DUF258 PF03193.11 CCU98557.1 - 0.0063 15.7 0.0 1.2 8.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 CCU98557.1 - 0.0071 15.0 0.0 2.6 6.5 0.0 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 CCU98557.1 - 0.0081 15.8 8.2 0.016 14.8 0.0 4.4 4 2 0 5 5 4 1 Archaeal ATPase MobB PF03205.9 CCU98557.1 - 0.013 15.1 0.0 4.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 CCU98557.1 - 0.016 14.1 0.0 0.54 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ResIII PF04851.10 CCU98557.1 - 0.018 14.9 0.0 3 7.6 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 CCU98557.1 - 0.024 14.1 6.0 7.5 5.8 0.0 4.2 3 2 1 5 5 5 0 AAA-like domain PhoH PF02562.11 CCU98557.1 - 0.034 13.3 0.0 1.6 7.9 0.0 3.0 4 0 0 4 4 4 0 PhoH-like protein SRP54 PF00448.17 CCU98557.1 - 0.043 13.2 0.0 12 5.2 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 CCU98557.1 - 0.065 12.7 0.1 8 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_3 PF07726.6 CCU98557.1 - 0.087 12.4 0.0 14 5.3 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IncA PF04156.9 CCU98557.1 - 0.088 12.3 7.9 0.38 10.3 5.5 2.2 1 0 0 1 1 1 0 IncA protein EMP24_GP25L PF01105.19 CCU98557.1 - 0.15 11.7 0.6 0.3 10.7 0.4 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD AAA_13 PF13166.1 CCU98557.1 - 0.31 9.4 9.8 0.51 8.7 6.5 1.5 2 0 0 2 2 2 0 AAA domain RabGAP-TBC PF00566.13 CCU98558.1 - 0.29 10.5 2.9 1.4 8.3 0.2 2.7 3 0 0 3 3 3 0 Rab-GTPase-TBC domain RabGAP-TBC PF00566.13 CCU98559.1 - 3e-12 46.4 1.0 4e-12 46.0 0.7 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Acyltransferase PF01553.16 CCU98560.1 - 9.6e-32 109.1 0.0 1.4e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase PRKCSH-like PF12999.2 CCU98561.1 - 2e-37 128.4 7.2 4.2e-37 127.3 5.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CCU98561.1 - 2.5e-31 108.2 1.8 2.6e-31 108.1 0.1 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CCU98561.1 - 2.7e-10 40.9 0.8 1.8e-09 38.2 0.7 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Sedlin_N PF04628.8 CCU98562.1 - 4e-15 55.8 0.0 7.7e-12 45.2 0.0 3.0 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CCU98562.1 - 7.3e-05 22.5 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Myb_DNA-binding PF00249.26 CCU98563.1 - 5.3e-37 125.6 18.7 3.8e-11 42.8 0.1 5.7 6 0 0 6 6 6 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCU98563.1 - 5.7e-28 96.8 4.2 3e-07 30.4 0.1 5.6 4 1 1 5 5 5 5 Myb-like DNA-binding domain Rap1_C PF11626.3 CCU98563.1 - 0.0054 16.5 7.0 6.3 6.7 1.6 4.0 2 1 1 4 4 4 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 CCU98563.1 - 0.21 11.7 15.0 0.9 9.7 0.3 5.4 5 2 0 5 5 5 0 Myb/SANT-like DNA-binding domain GTP_EFTU PF00009.22 CCU98564.1 - 1.1e-45 155.3 0.0 1.5e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCU98564.1 - 4.8e-05 23.2 0.0 0.00015 21.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 CCU98564.1 - 0.00026 21.0 0.1 0.00065 19.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Arf PF00025.16 CCU98564.1 - 0.004 16.4 0.0 2.9 7.0 0.0 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 CCU98564.1 - 0.0073 16.7 0.0 0.055 13.9 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein cobW PF02492.14 CCU98564.1 - 0.028 13.8 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.7 CCU98564.1 - 0.056 12.5 0.0 0.13 11.3 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CCU98564.1 - 0.12 10.9 0.1 0.21 10.2 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit HBS1_N PF08938.5 CCU98565.1 - 4.4e-11 42.7 4.5 5.1e-11 42.5 2.2 1.8 2 0 0 2 2 2 1 HBS1 N-terminus RRP7 PF12923.2 CCU98565.1 - 0.015 15.2 0.2 0.042 13.8 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Metal_resist PF13801.1 CCU98565.1 - 0.051 13.5 5.4 0.06 13.3 1.6 2.4 2 0 0 2 2 2 0 Heavy-metal resistance Iso_dh PF00180.15 CCU98566.1 - 1.2e-86 290.8 0.0 1.5e-86 290.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Med13_C PF06333.7 CCU98568.1 - 3e-05 22.7 0.6 3e-05 22.7 0.4 1.9 1 1 1 2 2 2 1 Mediator complex subunit 13 C-terminal ThiF PF00899.16 CCU98570.1 - 9e-49 164.7 0.1 9.4e-30 103.2 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 CCU98570.1 - 2.2e-40 137.6 0.0 4.1e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 CCU98570.1 - 5.5e-39 131.5 0.2 6.5e-26 89.6 0.0 3.0 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCU98570.1 - 1.8e-26 91.2 0.7 1.6e-22 78.6 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Arm PF00514.18 CCU98571.1 - 0.39 10.6 6.0 2.3 8.1 0.0 4.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat RNA_pol_Rpb1_5 PF04998.12 CCU98572.1 - 5e-96 321.1 0.1 7.2e-96 320.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CCU98572.1 - 2.6e-90 303.0 0.0 3.9e-90 302.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CCU98572.1 - 4.5e-66 221.8 0.0 9e-66 220.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CCU98572.1 - 8.8e-39 132.7 0.0 3.9e-38 130.6 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CCU98572.1 - 5.2e-31 106.5 0.0 1.2e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Chorein_N PF12624.2 CCU98572.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of Chorein, a TM vesicle-mediated sorter RRM_1 PF00076.17 CCU98573.1 - 3.9e-41 138.5 0.0 1.1e-20 73.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU98573.1 - 1.9e-34 117.4 0.0 6.7e-18 64.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU98573.1 - 1.2e-20 73.0 0.0 3.5e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCU98573.1 - 0.09 12.5 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif FAD_binding_6 PF00970.19 CCU98574.1 - 6.2e-15 55.1 0.0 1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 CCU98574.1 - 1e-08 35.5 0.6 1.7e-08 34.7 0.1 1.6 2 0 0 2 2 2 1 Globin NAD_binding_1 PF00175.16 CCU98574.1 - 6.4e-05 23.4 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.3 CCU98574.1 - 0.0037 16.9 0.2 0.01 15.5 0.0 1.8 2 1 0 2 2 2 1 Protoglobin NAD_binding_6 PF08030.7 CCU98574.1 - 0.0074 16.1 0.0 0.061 13.2 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Glyco_hydro_cc PF11790.3 CCU98575.1 - 1.1e-59 201.8 8.9 1.4e-59 201.4 6.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MTHFR PF02219.12 CCU98575.1 - 0.096 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase Aminotran_5 PF00266.14 CCU98577.1 - 1.1e-31 109.9 0.0 1.4e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Plasmid_Txe PF06769.8 CCU98577.1 - 0.1 12.4 0.0 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 Plasmid encoded toxin Txe TFIIF_beta PF02270.10 CCU98578.1 - 1.9e-53 182.0 0.0 4e-52 177.7 0.0 2.0 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DDE_Tnp_IS66_C PF13817.1 CCU98578.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 IS66 C-terminal element HSP70 PF00012.15 CCU98579.1 - 6.2e-271 899.6 6.6 7e-271 899.4 4.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCU98579.1 - 8.5e-16 57.4 0.1 2.4e-14 52.7 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CCU98579.1 - 0.022 14.3 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 CCU98579.1 - 0.027 13.5 0.1 0.085 11.9 0.1 1.8 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DUF4582 PF15189.1 CCU98579.1 - 0.03 13.5 0.1 0.082 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) FtsA PF14450.1 CCU98579.1 - 0.28 11.0 5.0 2.6 7.8 0.1 3.6 3 2 0 3 3 3 0 Cell division protein FtsA HOOK PF05622.7 CCU98580.1 - 1.5e-10 39.6 38.7 5.8e-06 24.4 4.6 3.2 1 1 2 3 3 3 3 HOOK protein YueH PF14166.1 CCU98580.1 - 3.2 7.5 5.1 2.4 7.9 0.3 2.6 2 0 0 2 2 2 0 YueH-like protein DUF837 PF05769.6 CCU98581.1 - 0.00017 21.1 6.3 0.0008 18.9 4.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF837) CCDC92 PF14916.1 CCU98581.1 - 0.039 13.5 2.4 0.25 10.9 0.0 2.9 2 1 1 3 3 3 0 Coiled-coil domain of unknown function DUF445 PF04286.7 CCU98581.1 - 0.074 12.5 0.8 0.11 11.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF725 PF05267.7 CCU98581.1 - 0.13 12.1 0.8 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF725) Bacillus_HBL PF05791.6 CCU98581.1 - 0.29 10.5 2.6 0.99 8.7 1.8 1.9 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.1 CCU98581.1 - 1 8.5 9.0 2 7.5 3.8 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 CCU98581.1 - 3.2 8.0 8.7 64 3.9 3.3 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF904) FlgM PF04316.8 CCU98581.1 - 4.8 7.2 7.2 4.8 7.1 0.0 3.7 4 1 0 4 4 4 0 Anti-sigma-28 factor, FlgM SlyX PF04102.7 CCU98581.1 - 8.9 6.7 12.0 1.5 9.2 0.2 3.5 4 0 0 4 4 4 0 SlyX DUF913 PF06025.7 CCU98582.1 - 2.1e-63 214.3 0.0 1.7e-60 204.8 0.0 3.8 2 1 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 CCU98582.1 - 7.7e-46 156.9 1.1 2.8e-44 151.7 0.0 3.2 3 1 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 CCU98582.1 - 1.1e-10 41.3 3.6 1.1e-10 41.3 2.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) UBA PF00627.26 CCU98582.1 - 2.2e-10 40.0 0.1 7.3e-10 38.3 0.1 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Cullin PF00888.17 CCU98583.1 - 2.3e-56 191.5 0.0 3e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Cullin family BPL_LplA_LipB PF03099.14 CCU98584.1 - 2.9e-13 49.9 0.0 6.9e-13 48.7 0.0 1.6 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.4 CCU98584.1 - 7.2e-05 21.7 0.0 0.0013 17.5 0.0 2.2 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal PrpR_N PF06506.6 CCU98584.1 - 0.062 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Propionate catabolism activator Hydrolase_6 PF13344.1 CCU98585.1 - 4.7e-29 100.2 0.0 8.4e-29 99.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCU98585.1 - 4.4e-17 61.5 0.0 1.1e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCU98585.1 - 2.4e-09 37.9 0.0 4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ion_trans PF00520.26 CCU98585.1 - 2.7e-06 26.7 1.3 2.7e-06 26.7 0.9 1.6 2 0 0 2 2 2 1 Ion transport protein HAD_2 PF13419.1 CCU98585.1 - 9.8e-06 25.8 0.0 0.0036 17.5 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 CCU98585.1 - 0.093 12.0 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.9 CCU98585.1 - 0.25 10.6 0.0 0.39 10.0 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Pkinase PF00069.20 CCU98586.1 - 1.2e-39 136.0 0.0 1.5e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98586.1 - 2.3e-17 62.9 0.0 2.9e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCU98586.1 - 2.7e-05 24.0 0.7 0.0033 17.2 0.0 2.7 2 1 0 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CCU98586.1 - 0.031 13.0 0.1 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AA_permease_2 PF13520.1 CCU98587.1 - 3.5e-62 210.3 50.8 4.2e-62 210.0 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCU98587.1 - 1.1e-36 126.2 43.3 1.4e-36 125.8 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease INTS5_N PF14837.1 CCU98587.1 - 1.5 8.1 5.5 0.11 11.8 0.3 1.6 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus DUF1129 PF06570.6 CCU98587.1 - 4.6 6.4 17.4 0.044 13.0 1.5 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1129) MFS_1 PF07690.11 CCU98588.1 - 1.3e-19 70.1 22.2 1.3e-19 70.1 15.4 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Utp11 PF03998.8 CCU98589.1 - 4e-56 190.5 15.7 5.2e-56 190.1 10.9 1.1 1 0 0 1 1 1 1 Utp11 protein CD20 PF04103.10 CCU98590.1 - 0.0015 18.4 1.6 0.0015 18.4 1.1 2.4 2 1 0 2 2 2 1 CD20-like family DUF1774 PF08611.5 CCU98590.1 - 0.028 14.5 0.4 0.028 14.5 0.3 2.7 2 2 1 3 3 3 0 Fungal protein of unknown function (DUF1774) SieB PF14163.1 CCU98590.1 - 2.6 7.5 6.6 2.9 7.4 0.6 2.5 2 1 0 2 2 2 0 Superinfection exclusion protein B DUF202 PF02656.10 CCU98590.1 - 9.4 6.5 19.7 1.1 9.4 0.5 3.7 2 2 0 2 2 2 0 Domain of unknown function (DUF202) Arrestin_N PF00339.24 CCU98591.1 - 4.2e-08 33.1 0.0 3.1e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ADH_N PF08240.7 CCU98592.1 - 6.6e-28 96.6 0.8 1.5e-27 95.4 0.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCU98592.1 - 3.4e-22 78.3 0.1 7.7e-22 77.2 0.1 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 CCU98592.1 - 0.05 13.1 0.3 0.081 12.4 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 CCU98592.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FGGY_C PF02782.11 CCU98593.1 - 3.1e-38 131.3 1.1 5.5e-38 130.5 0.7 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CCU98593.1 - 1.5e-20 73.5 0.0 6.7e-19 68.1 0.0 2.7 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain UPF0075 PF03702.9 CCU98593.1 - 0.057 12.3 0.1 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) BcrAD_BadFG PF01869.15 CCU98593.1 - 0.086 12.1 0.0 0.34 10.1 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Glyco_transf_21 PF13506.1 CCU98594.1 - 5e-22 78.0 1.2 7.3e-09 35.1 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 CCU98594.1 - 2.6e-15 56.8 1.2 3.9e-15 56.2 0.8 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 UQ_con PF00179.21 CCU98595.1 - 2.5e-40 137.1 0.1 2.7e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCU98595.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 CCU98595.1 - 0.037 13.9 1.7 0.073 12.9 1.2 1.7 1 1 0 1 1 1 0 RWD domain Tropomyosin_1 PF12718.2 CCU98596.1 - 8.2e-31 106.7 30.6 4e-30 104.5 21.2 1.8 1 1 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 CCU98596.1 - 1.3e-08 34.2 28.7 0.00067 18.8 2.9 3.0 1 1 2 3 3 3 3 Tropomyosin CCDC-167 PF15188.1 CCU98596.1 - 0.0027 17.6 5.1 0.0027 17.6 3.6 2.6 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 167 FliD_C PF07195.7 CCU98596.1 - 0.0043 16.3 5.2 0.0043 16.3 3.6 2.1 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus TMF_DNA_bd PF12329.3 CCU98596.1 - 0.023 14.5 10.1 0.023 14.5 7.0 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF725 PF05267.7 CCU98596.1 - 0.043 13.7 0.4 0.043 13.7 0.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF725) Reo_sigmaC PF04582.7 CCU98596.1 - 0.13 11.3 1.1 0.13 11.3 0.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Clr5 PF14420.1 CCU98596.1 - 0.16 11.9 1.3 0.34 10.8 0.9 1.5 1 0 0 1 1 1 0 Clr5 domain Uds1 PF15456.1 CCU98596.1 - 0.22 11.4 22.4 0.41 10.6 6.4 2.1 1 1 1 2 2 2 0 Up-regulated During Septation Prefoldin_3 PF13758.1 CCU98596.1 - 0.28 10.9 15.4 0.31 10.8 5.2 2.4 1 1 1 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.3 CCU98596.1 - 0.3 10.8 23.7 0.031 14.0 8.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fmp27_WPPW PF10359.4 CCU98596.1 - 0.45 8.8 19.8 1 7.6 6.1 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Ax_dynein_light PF10211.4 CCU98596.1 - 0.71 9.6 24.2 0.053 13.3 6.8 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Prefoldin PF02996.12 CCU98596.1 - 1.1 8.9 18.2 1.6 8.4 1.7 3.3 1 1 2 3 3 3 0 Prefoldin subunit Occludin_ELL PF07303.8 CCU98596.1 - 1.1 10.0 15.5 5.6 7.7 2.1 3.1 1 1 2 3 3 3 0 Occludin homology domain CENP-F_leu_zip PF10473.4 CCU98596.1 - 1.2 9.0 26.2 1.2e+02 2.4 16.9 2.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF883 PF05957.8 CCU98596.1 - 1.2 9.5 10.8 0.14 12.5 3.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) LIN37 PF15306.1 CCU98596.1 - 1.3 8.9 12.3 2.8 7.8 8.5 1.7 1 1 0 1 1 1 0 LIN37 NPV_P10 PF05531.7 CCU98596.1 - 1.4 9.2 7.0 5.7 7.2 2.4 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Utp11 PF03998.8 CCU98596.1 - 1.5 8.5 17.6 1.7 8.3 12.2 1.0 1 0 0 1 1 1 0 Utp11 protein DASH_Hsk3 PF08227.6 CCU98596.1 - 2.2 8.5 5.0 4.2 7.6 0.4 2.4 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like TPR_MLP1_2 PF07926.7 CCU98596.1 - 2.5 7.8 25.4 6 6.6 17.6 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlxA PF14282.1 CCU98596.1 - 2.5 8.1 22.1 87 3.1 15.3 2.4 1 1 0 1 1 1 0 FlxA-like protein NAD_binding_4 PF07993.7 CCU98596.1 - 2.6 6.8 10.0 0.48 9.3 0.6 2.1 1 1 0 2 2 2 0 Male sterility protein EHN PF06441.7 CCU98596.1 - 4.2 7.3 8.3 5.3 6.9 2.8 2.2 1 1 1 2 2 2 0 Epoxide hydrolase N terminus DUF4200 PF13863.1 CCU98596.1 - 4.5 7.2 28.8 5.8 6.8 5.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Mnd1 PF03962.10 CCU98596.1 - 4.9 6.7 20.6 6.8 6.3 6.0 2.2 1 1 1 2 2 2 0 Mnd1 family Prefoldin_2 PF01920.15 CCU98596.1 - 4.9 6.9 24.3 6.4 6.5 3.7 3.3 1 1 2 3 3 3 0 Prefoldin subunit UPF0184 PF03670.8 CCU98596.1 - 6.3 7.0 13.0 2.2 8.4 3.9 2.8 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) Adeno_PIX PF03955.9 CCU98596.1 - 9.2 6.8 15.1 5.7 7.5 2.7 2.9 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) DUF1664 PF07889.7 CCU98596.1 - 9.8 5.9 9.9 33 4.3 2.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pkinase PF00069.20 CCU98597.1 - 3.1e-50 170.7 0.0 5e-24 84.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98597.1 - 4.8e-15 55.3 0.0 2.8e-11 42.9 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CCU98597.1 - 0.0012 18.6 0.6 0.0051 16.5 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCU98597.1 - 0.011 14.8 1.2 0.014 14.5 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCU98597.1 - 0.03 13.3 0.1 0.071 12.0 0.0 1.5 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 CCU98597.1 - 0.1 11.9 0.1 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Myosin_head PF00063.16 CCU98599.1 - 1.4e-237 790.1 0.1 3.4e-237 788.8 0.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 CCU98599.1 - 2.2e-35 120.7 2.4 2.2e-35 120.7 1.7 2.1 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 CCU98599.1 - 1.4e-06 27.4 38.3 0.00021 20.6 0.4 7.0 7 0 0 7 7 7 4 IQ calmodulin-binding motif AAA_22 PF13401.1 CCU98599.1 - 7.1e-05 22.9 0.0 0.00036 20.6 0.0 2.3 1 0 0 1 1 1 1 AAA domain Fib_alpha PF08702.5 CCU98599.1 - 0.0058 16.7 7.1 0.013 15.6 4.1 2.2 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 CCU98599.1 - 0.078 12.7 18.7 0.8 9.4 11.8 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 CCU98599.1 - 0.081 11.3 6.9 0.13 10.7 4.7 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCU98599.1 - 0.47 10.7 3.3 2 8.7 0.0 2.8 2 1 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 CCU98599.1 - 0.48 9.7 0.0 0.48 9.7 0.0 2.5 2 1 0 2 2 1 0 AAA-like domain DUF342 PF03961.8 CCU98599.1 - 0.74 8.1 6.0 1.2 7.4 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TBPIP PF07106.8 CCU98599.1 - 1.7 8.1 14.7 1.5 8.3 3.0 2.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 CCU98599.1 - 1.7 8.6 17.6 0.027 14.4 4.7 2.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 CCU98599.1 - 2.6 7.0 15.8 5.1 6.0 10.9 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin PF02996.12 CCU98599.1 - 4.2 7.0 8.6 21 4.7 0.5 3.4 3 0 0 3 3 3 0 Prefoldin subunit AAA_23 PF13476.1 CCU98599.1 - 5.8 7.1 7.4 52 4.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AA_permease PF00324.16 CCU98600.1 - 7.3e-62 209.2 33.7 9e-62 208.9 23.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCU98600.1 - 1.1e-19 70.3 40.3 1.5e-19 69.8 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease PRP38 PF03371.10 CCU98601.1 - 9.8e-63 210.8 0.1 1.2e-62 210.5 0.1 1.1 1 0 0 1 1 1 1 PRP38 family Kinesin PF00225.18 CCU98602.1 - 6.4e-94 314.3 0.0 8.3e-94 314.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Oxidored_nitro PF00148.14 CCU98602.1 - 0.044 12.4 0.2 0.34 9.4 0.1 2.0 1 1 1 2 2 2 0 Nitrogenase component 1 type Oxidoreductase CCDC92 PF14916.1 CCU98602.1 - 0.044 13.3 0.2 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Muted PF14942.1 CCU98602.1 - 0.25 11.2 3.4 5.9 6.7 1.4 2.5 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Pox_A_type_inc PF04508.7 CCU98602.1 - 0.32 10.8 1.8 4.3 7.3 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat HALZ PF02183.13 CCU98602.1 - 0.47 10.2 2.3 9.7 6.0 0.2 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper FUSC PF04632.7 CCU98602.1 - 0.75 8.1 16.6 0.11 10.8 7.7 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family FlgN PF05130.7 CCU98602.1 - 2.3 8.4 10.3 0.94 9.7 4.1 2.3 2 1 0 2 2 2 0 FlgN protein AAA PF00004.24 CCU98603.1 - 3.7e-41 140.4 0.0 5e-40 136.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCU98603.1 - 4.6e-05 23.3 0.0 0.00074 19.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCU98603.1 - 0.00012 21.8 0.6 0.0006 19.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCU98603.1 - 0.00021 21.3 0.2 0.009 16.0 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCU98603.1 - 0.00025 21.2 0.4 0.019 15.1 0.3 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCU98603.1 - 0.00029 19.9 0.0 0.00063 18.8 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 CCU98603.1 - 0.00077 18.7 2.3 0.0078 15.4 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein AAA_17 PF13207.1 CCU98603.1 - 0.0039 17.9 0.1 0.012 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCU98603.1 - 0.0089 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCU98603.1 - 0.011 15.4 0.2 0.027 14.1 0.1 1.7 2 0 0 2 2 1 0 Part of AAA domain Mg_chelatase PF01078.16 CCU98603.1 - 0.011 14.8 0.0 0.04 13.0 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CCU98603.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_S19 PF00203.16 CCU98603.1 - 0.014 14.9 0.1 16 5.2 0.0 3.3 3 0 0 3 3 3 0 Ribosomal protein S19 IstB_IS21 PF01695.12 CCU98603.1 - 0.019 14.4 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.8 CCU98603.1 - 0.047 12.6 0.0 0.095 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.1 CCU98603.1 - 0.049 13.1 0.1 0.5 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CCU98603.1 - 0.052 12.9 1.4 0.37 10.1 0.1 2.4 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CCU98603.1 - 0.053 13.0 0.1 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.6 CCU98603.1 - 0.098 13.0 1.0 0.66 10.4 0.0 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Med4 PF10018.4 CCU98604.1 - 4.8e-19 68.4 0.5 7e-19 67.9 0.3 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Spectrin PF00435.16 CCU98604.1 - 0.0008 19.6 1.8 0.0013 19.0 1.3 1.3 1 0 0 1 1 1 1 Spectrin repeat FUSC PF04632.7 CCU98604.1 - 0.13 10.6 7.6 0.16 10.4 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2937 PF11157.3 CCU98604.1 - 0.16 11.3 6.3 0.37 10.1 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Pkinase PF00069.20 CCU98605.1 - 1.2e-54 185.1 0.0 1.8e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98605.1 - 1.9e-18 66.4 0.1 3.3e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCU98605.1 - 0.0004 20.2 0.3 0.0063 16.2 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CCU98605.1 - 0.00066 19.0 0.1 0.0015 17.9 0.1 1.5 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 CCU98605.1 - 0.037 13.5 0.1 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase HEAT_EZ PF13513.1 CCU98606.1 - 9.6e-26 89.5 14.8 3.6e-05 24.0 0.0 11.1 10 2 2 12 12 10 5 HEAT-like repeat HEAT PF02985.17 CCU98606.1 - 2.1e-16 58.4 7.7 0.0062 16.5 0.0 10.4 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.1 CCU98606.1 - 4.1e-16 59.0 21.8 0.0015 18.7 0.0 8.4 4 3 5 10 10 10 6 HEAT repeats Ipi1_N PF12333.3 CCU98606.1 - 1e-09 38.2 0.7 0.018 14.9 0.0 6.2 5 1 1 6 6 6 2 Rix1 complex component involved in 60S ribosome maturation Xpo1 PF08389.7 CCU98606.1 - 3.1e-08 33.6 4.7 0.0046 16.8 0.1 5.6 4 1 1 5 5 5 2 Exportin 1-like protein IBN_N PF03810.14 CCU98606.1 - 3.4e-07 30.0 1.6 1.6e-06 27.9 0.1 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 CCU98606.1 - 4e-06 26.3 0.6 0.19 11.0 0.0 4.8 5 2 0 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 CCU98606.1 - 4.7e-06 26.8 0.1 0.85 10.0 0.0 6.2 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region UME PF08064.8 CCU98606.1 - 1.7e-05 24.6 0.0 0.43 10.5 0.0 5.1 6 1 0 6 6 5 1 UME (NUC010) domain MMS19_C PF12460.3 CCU98606.1 - 3.7e-05 22.6 2.1 2.7 6.6 0.0 5.3 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 CCU98606.1 - 5.4e-05 21.7 1.3 0.16 10.2 0.1 3.9 4 1 0 4 4 4 2 Adaptin N terminal region Cohesin_HEAT PF12765.2 CCU98606.1 - 0.0069 16.3 0.1 5 7.1 0.0 3.5 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion MMS19_N PF14500.1 CCU98606.1 - 0.008 15.4 0.1 0.27 10.4 0.1 3.3 3 2 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.2 CCU98606.1 - 0.033 14.0 0.0 10 5.8 0.0 4.2 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF3437 PF11919.3 CCU98606.1 - 0.054 13.2 0.4 0.5 10.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) SWI-SNF_Ssr4 PF08549.5 CCU98607.1 - 9.1e-05 20.9 0.2 0.00022 19.7 0.0 1.7 1 1 1 2 2 2 1 Fungal domain of unknown function (DUF1750) Nop16 PF09420.5 CCU98607.1 - 0.0051 16.9 2.1 0.0066 16.5 1.4 1.3 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 IcmF-related PF06761.7 CCU98608.1 - 0.029 13.6 0.1 0.03 13.6 0.1 1.1 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing RabGAP-TBC PF00566.13 CCU98609.1 - 2.9e-08 33.4 0.0 2.9e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain BAR PF03114.13 CCU98610.1 - 2.8e-36 125.1 5.2 4.5e-36 124.4 3.6 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 CCU98610.1 - 8.2e-16 57.1 0.0 1.3e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCU98610.1 - 2e-13 49.6 0.1 3.1e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCU98610.1 - 7.5e-12 44.5 0.0 1.1e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2935 PF11155.3 CCU98610.1 - 0.0016 18.5 4.5 1.1 9.4 0.0 3.3 3 1 1 4 4 4 2 Domain of unknown function (DUF2935) DUF3209 PF11483.3 CCU98610.1 - 0.072 13.4 1.4 9.1 6.6 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) IF-2B PF01008.12 CCU98611.1 - 8.4e-70 234.9 0.0 1.5e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family Med3 PF11593.3 CCU98611.1 - 0.37 9.9 3.9 0.5 9.5 2.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Dynein_light PF01221.13 CCU98612.1 - 4.6e-31 106.6 2.6 8.8e-31 105.7 1.8 1.5 1 1 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 CCU98612.1 - 0.0016 18.7 0.1 0.0021 18.3 0.1 1.2 1 0 0 1 1 1 1 Ground-like domain Casc1 PF12366.3 CCU98612.1 - 0.073 12.5 0.5 2 7.8 0.3 2.0 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 MutL_C PF08676.6 CCU98613.1 - 6.1e-19 68.0 0.0 1.4e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 CCU98613.1 - 5.2e-18 64.6 0.0 9.3e-18 63.8 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CCU98613.1 - 0.065 12.8 1.7 0.26 10.9 0.4 2.6 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WD40 PF00400.27 CCU98614.1 - 7.5e-06 25.6 0.1 2.2e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat V-ATPase_G PF03179.10 CCU98615.1 - 5.8e-27 94.0 19.7 7e-27 93.7 13.6 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.3 CCU98615.1 - 0.00021 20.5 15.0 0.00026 20.2 10.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) HrpE PF06188.7 CCU98615.1 - 0.0043 16.8 4.6 0.0056 16.4 3.2 1.2 1 0 0 1 1 1 1 HrpE/YscL/FliH and V-type ATPase subunit E SseC PF04888.7 CCU98615.1 - 0.0075 15.6 2.8 0.012 14.9 2.0 1.3 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ATP-synt_B PF00430.13 CCU98615.1 - 0.01 15.6 15.1 0.01 15.6 10.5 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Herpes_UL14 PF03580.9 CCU98615.1 - 0.074 12.8 6.5 0.082 12.7 3.9 1.5 1 1 0 1 1 1 0 Herpesvirus UL14-like protein Clathrin_lg_ch PF01086.12 CCU98615.1 - 0.092 12.6 11.8 0.14 12.1 8.2 1.2 1 0 0 1 1 1 0 Clathrin light chain DUF342 PF03961.8 CCU98615.1 - 0.28 9.5 9.5 0.33 9.3 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HAUS6_N PF14661.1 CCU98615.1 - 0.32 10.3 7.3 0.41 9.9 5.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RRF PF01765.14 CCU98615.1 - 0.43 10.0 13.3 0.67 9.4 9.2 1.4 1 0 0 1 1 1 0 Ribosome recycling factor DUF3402 PF11882.3 CCU98615.1 - 0.74 8.7 8.7 0.88 8.5 6.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) YlqD PF11068.3 CCU98615.1 - 0.84 9.6 14.0 0.77 9.7 8.8 1.6 1 1 0 1 1 1 0 YlqD protein MtrG PF04210.8 CCU98615.1 - 1.1 8.9 3.0 1.2 8.8 0.6 1.9 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF3435 PF11917.3 CCU98615.1 - 1.1 7.8 9.5 1.3 7.6 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Iron_permease PF04120.7 CCU98615.1 - 1.1 8.7 5.4 1.6 8.3 3.5 1.5 1 1 0 1 1 1 0 Low affinity iron permease PTPlike_phytase PF14566.1 CCU98615.1 - 1.2 9.2 4.7 1.5 8.8 3.3 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF2115 PF09888.4 CCU98615.1 - 1.8 8.6 5.4 2.6 8.1 3.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) She9_MDM33 PF05546.6 CCU98615.1 - 1.8 8.0 12.3 2.4 7.6 8.5 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family DUF883 PF05957.8 CCU98615.1 - 2.6 8.4 9.8 31 5.0 2.5 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.8 CCU98615.1 - 3.6 6.5 10.3 4.5 6.2 7.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.1 CCU98615.1 - 3.7 6.4 8.3 4.8 6.0 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MMR_HSR1_C PF08438.5 CCU98615.1 - 4.2 7.6 6.5 7.3 6.8 4.3 1.6 1 1 0 1 1 1 0 GTPase of unknown function C-terminal Exonuc_VII_L PF02601.10 CCU98615.1 - 4.5 6.3 10.2 5.3 6.1 7.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FliT PF05400.8 CCU98615.1 - 4.9 7.6 13.9 15 6.0 0.1 2.4 1 1 1 2 2 2 0 Flagellar protein FliT Phage_GPO PF05929.6 CCU98615.1 - 5.9 6.0 10.1 4.9 6.3 6.1 1.4 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Spore_GerAC PF05504.6 CCU98615.1 - 6.3 6.5 11.6 13 5.4 8.0 1.5 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Symplekin_C PF12295.3 CCU98616.1 - 2.1e-54 184.2 0.0 4.3e-54 183.2 0.0 1.5 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 CCU98616.1 - 7.3e-38 130.3 0.0 1.3e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Trp_syntA PF00290.15 CCU98617.1 - 1.3e-85 286.0 0.1 2.9e-85 284.9 0.1 1.6 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 CCU98617.1 - 7.8e-43 146.8 1.3 1.4e-42 146.0 0.9 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.20 CCU98618.1 - 1.1e-58 198.5 0.0 1.7e-58 197.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98618.1 - 5.2e-38 130.6 0.0 7.6e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CCU98618.1 - 3.3e-19 69.0 0.0 1.3e-18 67.1 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain Rad9 PF04139.8 CCU98618.1 - 1e-11 44.4 0.1 1.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Rad9 Kinase-like PF14531.1 CCU98618.1 - 6.6e-06 25.2 0.1 1.7e-05 23.9 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CCU98618.1 - 0.013 15.2 0.0 0.16 11.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family UDPGP PF01704.13 CCU98620.1 - 4.8e-49 166.9 0.0 6.2e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CCU98620.1 - 0.0044 17.1 0.0 0.013 15.5 0.0 2.0 1 1 0 1 1 1 1 MobA-like NTP transferase domain tRNA_bind PF01588.15 CCU98621.1 - 4.5e-25 87.3 0.0 7.8e-25 86.5 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 CCU98621.1 - 2.3e-05 24.7 0.1 6.6e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCU98621.1 - 9.6e-05 22.2 0.0 0.00038 20.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCU98621.1 - 0.00018 21.4 0.0 0.00018 21.4 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain LRR_4 PF12799.2 CCU98622.1 - 2.4e-20 71.6 21.5 9.5e-07 28.3 0.9 5.3 3 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCU98622.1 - 1.4e-14 53.6 20.5 2e-10 40.2 2.8 4.5 2 2 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 CCU98622.1 - 3e-11 41.7 16.3 0.53 10.5 0.0 8.2 8 1 0 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.1 CCU98622.1 - 2.9e-08 32.9 22.2 0.053 13.5 0.0 8.0 8 0 0 8 8 8 3 Leucine Rich repeat LRR_7 PF13504.1 CCU98622.1 - 8.1e-08 31.2 25.1 0.12 12.6 0.1 8.6 8 0 0 8 8 8 3 Leucine rich repeat zf-CCCH PF00642.19 CCU98622.1 - 4e-05 23.1 6.8 0.0011 18.6 0.5 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_3 PF07725.7 CCU98622.1 - 0.015 15.0 11.6 0.12 12.1 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat zf-CCCH_2 PF14608.1 CCU98622.1 - 7.3 6.7 13.2 0.74 9.9 3.4 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type GCV_T PF01571.16 CCU98623.1 - 1e-59 201.4 0.0 1.7e-59 200.7 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CCU98623.1 - 5e-25 87.3 0.1 9.9e-25 86.4 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CCU98623.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family ABC_tran PF00005.22 CCU98624.1 - 2.1e-43 147.9 0.0 8.5e-26 90.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCU98624.1 - 4.5e-40 137.7 33.2 1.4e-28 100.0 7.7 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CCU98624.1 - 6.9e-11 41.7 0.3 0.0065 15.7 0.1 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CCU98624.1 - 6e-08 32.8 2.2 0.0004 20.4 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 CCU98624.1 - 1.1e-07 32.0 0.0 0.015 15.2 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 CCU98624.1 - 1.5e-07 30.8 0.0 5.2e-05 22.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCU98624.1 - 1.5e-06 28.4 0.1 0.11 12.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 CCU98624.1 - 3.7e-05 22.7 0.0 0.003 16.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 CCU98624.1 - 8.5e-05 22.9 0.0 0.026 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CCU98624.1 - 0.00032 20.2 0.0 0.15 11.5 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.24 CCU98624.1 - 0.00056 20.1 0.0 0.17 12.1 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCU98624.1 - 0.0032 17.1 0.1 2.8 7.5 0.0 2.8 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 CCU98624.1 - 0.0051 16.2 0.8 2.9 7.3 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 CCU98624.1 - 0.0065 15.8 0.0 0.18 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CCU98624.1 - 0.0068 16.9 0.0 2.6 8.5 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 CCU98624.1 - 0.0074 15.8 0.0 0.73 9.3 0.0 2.7 3 0 0 3 3 2 1 Conserved hypothetical ATP binding protein MobB PF03205.9 CCU98624.1 - 0.0081 15.8 0.0 0.035 13.8 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 CCU98624.1 - 0.01 14.4 0.0 2.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.18 CCU98624.1 - 0.012 15.5 0.0 0.49 10.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 CCU98624.1 - 0.014 14.8 0.0 0.098 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_5 PF07728.9 CCU98624.1 - 0.014 15.0 0.1 3.5 7.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 CCU98624.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_33 PF13671.1 CCU98624.1 - 0.016 15.0 0.3 1.7 8.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 CCU98624.1 - 0.018 15.1 0.0 4.1 7.6 0.0 2.7 3 0 0 3 3 2 0 RNA helicase DUF258 PF03193.11 CCU98624.1 - 0.02 14.0 0.0 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCU98624.1 - 0.021 15.6 0.0 0.12 13.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 CCU98624.1 - 0.029 14.0 0.0 6.6 6.3 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 CCU98624.1 - 0.037 12.9 0.1 4.7 5.9 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain IstB_IS21 PF01695.12 CCU98624.1 - 0.039 13.3 0.1 3.5 6.9 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.4 CCU98624.1 - 0.071 12.5 0.1 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 CCU98624.1 - 0.084 12.7 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CCU98624.1 - 0.1 11.7 0.0 5.5 6.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 CCU98624.1 - 0.18 12.1 0.1 4.1 7.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain ArgK PF03308.11 CCU98624.1 - 0.23 10.2 0.0 0.41 9.3 0.0 1.3 1 0 0 1 1 1 0 ArgK protein DAP3 PF10236.4 CCU98624.1 - 0.29 10.0 0.8 15 4.3 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 KaiC PF06745.8 CCU98624.1 - 0.32 10.0 0.0 15 4.5 0.0 2.3 2 0 0 2 2 2 0 KaiC NUFIP1 PF10453.4 CCU98625.1 - 3.6e-13 48.8 0.2 6.6e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Nop14 PF04147.7 CCU98625.1 - 0.86 7.4 5.3 0.35 8.7 1.8 1.6 2 0 0 2 2 2 0 Nop14-like family Macoilin PF09726.4 CCU98625.1 - 2 6.5 5.4 2.7 6.1 3.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 CCU98625.1 - 2.4 7.4 26.9 0.018 14.4 9.4 2.1 2 0 0 2 2 2 0 Vta1 like Ribosomal_L4 PF00573.17 CCU98626.1 - 5.1e-58 195.6 0.0 6.4e-58 195.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.14 CCU98627.1 - 8.3e-42 142.2 0.4 9.5e-42 142.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 SWIB PF02201.13 CCU98628.1 - 2.4e-13 49.5 0.0 4.5e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Ras PF00071.17 CCU98629.1 - 1.4e-58 196.8 0.0 1.7e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU98629.1 - 1e-20 74.4 0.0 1.5e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCU98629.1 - 9.9e-18 63.9 0.0 7.5e-17 61.1 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCU98629.1 - 1e-10 41.1 0.0 1.3e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCU98629.1 - 3.8e-05 23.1 0.0 0.00011 21.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCU98629.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CCU98629.1 - 0.0019 18.2 0.0 0.0039 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 CCU98629.1 - 0.025 13.8 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 CCU98629.1 - 0.026 13.7 0.1 0.069 12.3 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 CCU98629.1 - 0.026 14.2 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 CCU98629.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mito_carr PF00153.22 CCU98630.1 - 4.8e-64 212.0 4.4 7.5e-24 83.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SEP PF08059.8 CCU98631.1 - 3.2e-25 88.2 0.0 1.5e-24 86.1 0.0 2.1 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.1 CCU98631.1 - 1e-08 34.5 0.0 1.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 CCU98631.1 - 9.5e-07 28.7 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Tim17 PF02466.14 CCU98632.1 - 1.5e-11 44.4 13.7 2e-11 44.0 9.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 CCU98632.1 - 0.67 9.6 21.6 0.17 11.5 7.4 2.3 1 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 CCU98632.1 - 2.3 7.8 25.6 0.13 11.8 8.2 2.5 2 1 0 2 2 2 0 YMGG-like Gly-zipper Peptidase_M1 PF01433.15 CCU98633.1 - 1.4e-106 356.8 0.0 2.4e-68 230.9 0.0 2.3 1 1 0 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 CCU98633.1 - 1.5e-60 205.1 0.9 2e-60 204.7 0.6 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CCU98633.1 - 8.4e-14 51.7 0.1 2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M1 PF01433.15 CCU98634.1 - 3.7e-93 312.7 0.0 2.1e-60 204.8 0.0 2.9 3 0 0 3 3 3 2 Peptidase family M1 ERAP1_C PF11838.3 CCU98634.1 - 2.1e-52 178.4 4.0 2.1e-52 178.4 2.7 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CCU98634.1 - 3.4e-17 62.6 0.5 8.9e-17 61.3 0.3 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Aldo_ket_red PF00248.16 CCU98635.1 - 1.5e-44 151.9 0.0 2.1e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_M19 PF01244.16 CCU98635.1 - 0.077 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Peptidase_M1 PF01433.15 CCU98636.1 - 2e-93 313.5 0.0 1.1e-62 212.4 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 CCU98636.1 - 1.1e-53 182.6 5.8 1.5e-53 182.1 4.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CCU98636.1 - 5.5e-14 52.3 0.6 5.5e-14 52.3 0.4 2.7 3 0 0 3 3 3 1 Peptidase MA superfamily Aminotran_1_2 PF00155.16 CCU98638.1 - 5.6e-46 157.1 0.0 6.5e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCU98638.1 - 0.0014 17.8 0.2 0.02 14.0 0.0 2.2 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 CCU98638.1 - 0.0014 16.9 0.0 0.0027 16.0 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CCU98638.1 - 0.0021 17.1 0.1 0.0039 16.2 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Vps39_1 PF10366.4 CCU98639.1 - 1.1e-20 73.6 0.0 4.3e-20 71.7 0.0 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 CCU98639.1 - 8.8e-17 61.2 0.0 2.3e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 CCU98639.1 - 1.6e-07 31.0 0.0 6.3e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 CCU98639.1 - 0.00056 19.5 0.0 0.4 10.2 0.0 2.6 3 0 0 3 3 3 2 Region in Clathrin and VPS PapD-like PF14874.1 CCU98640.1 - 2.7e-07 30.4 0.1 0.012 15.5 0.0 3.9 4 0 0 4 4 4 3 Flagellar-associated PapD-like Kinesin PF00225.18 CCU98641.1 - 1.7e-104 349.1 0.0 2.4e-104 348.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain AIP3 PF03915.8 CCU98641.1 - 0.00031 19.7 1.4 0.0004 19.4 0.1 1.8 2 0 0 2 2 2 1 Actin interacting protein 3 Ribosomal_L29 PF00831.18 CCU98641.1 - 0.012 15.2 4.1 5.1 6.8 0.1 3.9 4 0 0 4 4 4 0 Ribosomal L29 protein Bac_DnaA PF00308.13 CCU98641.1 - 0.02 14.5 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein BBP1_C PF15272.1 CCU98641.1 - 2.1 7.8 7.0 2.6 7.5 0.2 2.7 2 1 1 3 3 3 0 Spindle pole body component BBP1, C-terminal Jnk-SapK_ap_N PF09744.4 CCU98641.1 - 5.9 6.8 11.1 1.5 8.7 4.8 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 NPR3 PF03666.8 CCU98643.1 - 8.5e-55 186.0 0.5 9e-44 149.7 0.1 2.3 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 CCU98643.1 - 4.7e-06 25.5 0.1 2.9e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Nitrogen permease regulator 2 CN_hydrolase PF00795.17 CCU98645.1 - 0.0001 21.6 0.0 0.00057 19.2 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase BolA PF01722.13 CCU98646.1 - 5.4e-18 64.7 0.0 1e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein UvrD-helicase PF00580.16 CCU98647.1 - 1.4e-14 54.0 0.0 9.6e-11 41.5 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 CCU98647.1 - 2.4e-11 43.7 0.0 3.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 CCU98647.1 - 6.2e-10 39.1 0.0 1.6e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CCU98647.1 - 1.4e-08 34.5 0.0 0.021 14.3 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CCU98647.1 - 7.9e-07 28.7 0.0 3.2e-06 26.7 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCU98647.1 - 2.8e-06 27.0 0.0 0.00036 20.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CCU98647.1 - 0.002 17.3 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.1 CCU98647.1 - 0.0083 16.2 0.0 1.1 9.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF4287 PF14117.1 CCU98647.1 - 0.087 12.5 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) AAA_12 PF13087.1 CCU98647.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain HEAT_2 PF13646.1 CCU98648.1 - 0.0026 17.9 1.5 0.0026 17.9 1.0 5.6 6 1 0 6 6 6 1 HEAT repeats Anticodon_1 PF08264.8 CCU98648.1 - 0.024 14.3 0.2 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA HEAT PF02985.17 CCU98648.1 - 0.16 12.1 8.5 2.9 8.2 0.1 5.5 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 CCU98648.1 - 2.1 8.9 28.5 1.9 9.1 0.4 7.2 6 1 1 7 7 7 0 HEAT-like repeat NosD PF05048.8 CCU98649.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Sec63 PF02889.11 CCU98650.1 - 5.6e-176 584.2 0.0 3.3e-90 302.5 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CCU98650.1 - 3.7e-49 166.4 0.0 1.6e-28 99.2 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 CCU98650.1 - 3.1e-14 53.2 0.0 5.1e-10 39.4 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCU98650.1 - 1.2e-11 44.2 0.0 7.8e-09 35.2 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCU98650.1 - 1.7e-07 31.4 0.0 0.022 14.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 CCU98650.1 - 0.0017 18.0 0.0 0.12 12.1 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 CCU98650.1 - 0.012 15.8 0.2 7 6.8 0.2 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CCU98650.1 - 0.027 13.5 0.0 1.5 7.8 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin DJ-1_PfpI PF01965.19 CCU98651.1 - 3.6e-16 58.9 0.1 4.4e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CCU98651.1 - 1.4e-13 50.4 0.0 1.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase SNO PF01174.14 CCU98651.1 - 0.00053 19.6 0.0 0.00067 19.3 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 CCU98651.1 - 0.011 15.3 0.2 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 CCU98651.1 - 0.017 14.5 0.0 0.027 13.9 0.0 1.3 2 0 0 2 2 2 0 Glutamine amidotransferase class-I AMP-binding PF00501.23 CCU98652.1 - 9e-76 254.9 0.0 1.6e-74 250.8 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCU98652.1 - 0.016 16.1 0.0 0.041 14.8 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ELYS PF13934.1 CCU98653.1 - 1.4e-13 51.1 0.1 4.4e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 Nuclear pore complex assembly HMG-CoA_red PF00368.13 CCU98654.1 - 8.4e-160 531.4 1.7 1.1e-159 531.1 1.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 CCU98654.1 - 8.5e-12 44.7 1.4 1.4e-06 27.8 0.1 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CCU98654.1 - 1.5 6.6 2.8 5.3 4.8 2.0 1.6 1 1 0 1 1 1 0 Patched family CLU PF13236.1 CCU98655.1 - 1.4e-68 230.6 0.0 2.2e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 CCU98655.1 - 1.7e-41 141.9 0.0 3.6e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 CCU98655.1 - 1.7e-18 66.3 8.2 3.3e-08 33.3 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 CCU98655.1 - 9.5e-17 60.3 5.4 6.4e-07 29.1 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.1 CCU98655.1 - 3.2e-06 27.2 0.0 1e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_2 PF07719.12 CCU98655.1 - 0.02 14.8 0.5 14 5.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF727 PF05303.7 CCU98655.1 - 0.22 11.2 0.0 1 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF727) DUF874 PF05917.6 CCU98655.1 - 0.74 8.6 5.7 1.2 7.9 4.0 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) TraV PF09676.5 CCU98655.1 - 2.1 9.0 8.2 0.11 13.2 0.9 2.5 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Vps36_ESCRT-II PF11605.3 CCU98656.1 - 7.2e-20 70.5 0.0 1.2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.11 CCU98656.1 - 3.5e-09 36.1 0.0 7.2e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 EAP30/Vps36 family zf-RanBP PF00641.13 CCU98656.1 - 0.00033 19.6 3.6 0.00033 19.6 2.5 2.6 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DUF2459 PF09601.5 CCU98656.1 - 0.0088 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2459) GRAM PF02893.15 CCU98656.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 GRAM domain DZR PF12773.2 CCU98656.1 - 0.35 10.7 9.9 2.8 7.8 7.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_2 PF14445.1 CCU98656.1 - 0.94 9.4 6.5 2.3 8.2 4.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Methyltransf_23 PF13489.1 CCU98657.1 - 9e-25 87.2 0.0 2.4e-24 85.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCU98657.1 - 3.5e-18 65.8 0.0 7.6e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCU98657.1 - 2e-14 53.4 0.0 1.3e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCU98657.1 - 7.8e-14 52.2 0.3 2.7e-13 50.4 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCU98657.1 - 3.8e-13 49.7 0.0 8.6e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCU98657.1 - 2e-10 40.9 0.1 4.5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCU98657.1 - 6.4e-08 32.0 0.1 8.2e-07 28.3 0.1 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 CCU98657.1 - 2.1e-07 30.9 0.7 2.1e-07 30.9 0.5 1.9 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCU98657.1 - 3e-06 26.5 0.0 4.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 CCU98657.1 - 3.8e-06 26.2 0.0 5.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CCU98657.1 - 0.00015 21.1 0.1 0.00033 20.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 CCU98657.1 - 0.0046 15.6 0.1 0.02 13.6 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) TPMT PF05724.6 CCU98657.1 - 0.048 13.1 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) NodS PF05401.6 CCU98657.1 - 0.052 12.9 0.1 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 CCU98657.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Gaa1 PF04114.9 CCU98658.1 - 2.6e-42 145.2 7.9 4.5e-23 81.7 0.1 4.0 2 2 0 2 2 2 2 Gaa1-like, GPI transamidase component WD40 PF00400.27 CCU98659.1 - 1.2e-61 202.4 16.6 3.9e-10 39.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CCU98659.1 - 1.2e-09 38.2 0.0 0.0004 20.1 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CCU98659.1 - 0.0012 18.3 0.0 0.12 11.8 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 CCU98659.1 - 0.11 11.2 0.0 0.36 9.5 0.0 1.8 1 1 1 2 2 2 0 Coatomer WD associated region Nucleoporin_N PF08801.6 CCU98659.1 - 0.18 10.5 0.5 43 2.6 0.0 3.4 1 1 2 3 3 3 0 Nup133 N terminal like PH PF00169.24 CCU98660.1 - 1.9e-07 31.2 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 PH domain CENP-B_dimeris PF09026.5 CCU98660.1 - 0.015 15.5 4.5 0.033 14.4 3.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 CCU98660.1 - 0.14 11.7 3.8 0.25 10.8 2.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 CCU98660.1 - 0.24 11.7 3.8 0.55 10.5 2.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.14 CCU98660.1 - 0.41 11.0 8.2 0.071 13.5 0.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Lactamase_B_2 PF12706.2 CCU98661.1 - 3.2e-28 98.6 0.1 1.8e-27 96.1 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CCU98661.1 - 1.2e-15 56.6 0.1 4.5e-15 54.8 0.0 2.0 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 CCU98661.1 - 7.2e-07 29.0 0.0 7.1e-06 25.8 0.1 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily RNase_P_Rpp14 PF01900.14 CCU98661.1 - 0.029 14.2 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Rpp14/Pop5 family Cyt-b5 PF00173.23 CCU98662.1 - 2.9e-21 75.0 0.1 6.4e-21 73.9 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CCU98662.1 - 1.3e-08 35.1 29.9 1.6e-08 34.8 17.1 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DEAD PF00270.24 CCU98663.1 - 2.7e-38 131.1 0.0 4.9e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU98663.1 - 2.3e-20 72.2 0.0 6.5e-20 70.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCU98663.1 - 4.6e-11 42.8 0.0 3.7e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CCU98663.1 - 0.0013 17.7 0.1 0.28 10.0 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 CCU98663.1 - 0.0038 16.9 0.6 0.021 14.5 0.2 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CCU98663.1 - 0.043 13.9 5.8 0.26 11.4 0.3 3.7 3 1 0 3 3 3 0 AAA domain Flavi_DEAD PF07652.9 CCU98663.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain DnaJ PF00226.26 CCU98664.1 - 1.5e-17 63.0 3.4 3.4e-17 61.9 1.4 2.2 2 0 0 2 2 2 1 DnaJ domain TRAM_LAG1_CLN8 PF03798.11 CCU98665.1 - 1.5e-20 73.5 7.3 3.4e-20 72.4 5.1 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 CCU98665.1 - 3.2e-14 52.1 0.5 2.9e-12 45.8 0.1 2.5 2 0 0 2 2 2 2 TRAM1-like protein Acetyltransf_1 PF00583.19 CCU98666.1 - 1.9e-09 37.3 0.0 5.1e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCU98666.1 - 1.4e-08 34.7 0.0 7.2e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCU98666.1 - 0.0004 20.1 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 CCU98666.1 - 0.006 16.4 0.0 0.021 14.7 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 CCU98666.1 - 0.012 15.3 0.0 0.064 13.0 0.0 2.1 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_10 PF13673.1 CCU98666.1 - 0.04 14.0 0.0 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCU98666.1 - 0.076 12.7 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 FR47-like protein Mss4 PF04421.8 CCU98666.1 - 0.076 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Mss4 protein Toxin_37 PF11415.3 CCU98666.1 - 0.093 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Antifungal peptide termicin GNAT_acetyltr_2 PF13718.1 CCU98666.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Pro_isomerase PF00160.16 CCU98667.1 - 1.7e-48 164.7 0.2 2e-48 164.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Actin PF00022.14 CCU98668.1 - 2.8e-53 180.7 0.0 3.5e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCU98668.1 - 0.015 13.9 0.0 0.027 13.0 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein PilM_2 PF11104.3 CCU98668.1 - 0.026 13.4 0.0 0.27 10.0 0.0 2.0 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; CHCH PF06747.8 CCU98669.1 - 2.8e-09 36.6 1.8 4.2e-09 36.0 1.2 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 CCU98669.1 - 0.0026 17.7 2.6 0.0051 16.8 1.8 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 A_deaminase PF00962.17 CCU98669.1 - 0.02 13.8 0.0 0.022 13.6 0.0 1.0 1 0 0 1 1 1 0 Adenosine/AMP deaminase COX6B PF02297.12 CCU98669.1 - 0.17 11.8 1.9 0.23 11.4 1.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 CCU98669.1 - 0.79 9.5 6.2 1.3 8.8 2.9 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Aminotran_1_2 PF00155.16 CCU98670.1 - 1.4e-42 145.9 0.0 1.9e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCU98670.1 - 0.07 12.2 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DNA_pol3_delta2 PF13177.1 CCU98671.1 - 4e-10 39.5 0.7 5.5e-10 39.1 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CCU98671.1 - 0.0011 19.1 0.3 0.0021 18.2 0.2 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CCU98671.1 - 0.012 15.5 0.0 0.06 13.3 0.0 2.2 2 0 0 2 2 2 0 Replication factor C C-terminal domain SNF2_N PF00176.18 CCU98671.1 - 0.021 13.6 0.1 0.027 13.2 0.1 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain DNA_pol3_delta PF06144.8 CCU98671.1 - 0.03 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF1537 PF07005.6 CCU98671.1 - 0.1 12.2 0.7 0.17 11.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 AAA_22 PF13401.1 CCU98671.1 - 0.12 12.4 1.8 0.15 12.2 0.6 1.7 2 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 CCU98671.1 - 0.29 10.7 2.9 0.78 9.3 1.8 1.9 1 1 0 1 1 1 0 Bacterial dnaA protein Peptidase_S9 PF00326.16 CCU98672.1 - 6.3e-54 182.4 0.2 1.1e-53 181.6 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCU98672.1 - 2.5e-14 53.2 0.3 4.1e-14 52.5 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CCU98672.1 - 0.00022 20.7 0.1 0.0004 19.8 0.1 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.7 CCU98672.1 - 0.0022 16.5 0.4 0.15 10.5 0.0 2.7 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 CCU98672.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 CCU98672.1 - 0.015 14.8 0.0 0.044 13.3 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 CCU98672.1 - 0.075 12.3 0.0 0.37 10.0 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Proteasome PF00227.21 CCU98673.1 - 1.2e-19 70.3 0.0 1.8e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.12 CCU98673.1 - 0.095 12.3 0.1 0.62 9.6 0.0 2.2 2 1 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Phyto_Pns9_10 PF05878.6 CCU98673.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Nsp1_C PF05064.8 CCU98674.1 - 2.7e-29 101.1 0.4 5.3e-29 100.2 0.3 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 CCU98674.1 - 5.7e-24 84.5 146.9 2.7e-09 37.2 25.0 6.2 1 1 6 7 7 7 6 Nucleoporin FG repeat region LTXXQ PF07813.7 CCU98674.1 - 0.0024 18.3 2.6 0.0058 17.0 1.8 1.7 1 0 0 1 1 1 1 LTXXQ motif family protein IncA PF04156.9 CCU98674.1 - 0.07 12.7 4.2 0.028 14.0 1.2 1.5 2 0 0 2 2 2 0 IncA protein DUF4407 PF14362.1 CCU98674.1 - 0.082 11.8 1.6 0.12 11.3 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.3 CCU98674.1 - 0.3 10.8 3.7 7 6.3 0.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 CCU98674.1 - 0.46 9.4 3.9 0.69 8.8 2.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V-SNARE PF05008.10 CCU98674.1 - 3.2 7.9 4.9 2 8.6 1.1 2.2 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Aa_trans PF01490.13 CCU98675.1 - 2.8e-53 180.8 14.8 3.6e-53 180.5 10.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Herpes_gE PF02480.11 CCU98675.1 - 0.79 7.9 3.5 0.36 9.0 0.9 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E HhH-GPD PF00730.20 CCU98676.1 - 2.3e-13 50.3 0.0 4.7e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CCU98676.1 - 0.15 11.8 0.5 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif PC_rep PF01851.17 CCU98677.1 - 9.9e-14 50.7 16.6 0.00025 21.1 0.0 8.8 10 0 0 10 10 10 5 Proteasome/cyclosome repeat RNA_pol_Rbc25 PF08292.7 CCU98682.1 - 8.2e-32 109.9 0.0 1.6e-31 109.0 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CCU98682.1 - 5.5e-15 55.2 0.0 1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 SNF2_N PF00176.18 CCU98683.1 - 5.5e-05 22.0 0.1 6.6e-05 21.8 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain CS PF04969.11 CCU98684.1 - 4.7e-12 46.2 0.0 7e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 CS domain Ribosomal_S11 PF00411.14 CCU98685.1 - 3.1e-41 139.9 0.6 3.7e-41 139.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 CCU98685.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF814) DUF2252 PF10009.4 CCU98685.1 - 0.13 11.1 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Ribosomal_L38e PF01781.13 CCU98686.1 - 2.6e-31 107.1 1.1 2.9e-31 107.0 0.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family FHA PF00498.21 CCU98687.1 - 1.4e-17 63.5 0.0 2.3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain TPR_1 PF00515.23 CCU98688.1 - 4.7e-27 92.4 13.1 4.8e-05 22.7 0.2 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 CCU98688.1 - 1.7e-25 88.4 18.1 8.7e-10 38.1 0.5 6.3 5 1 0 6 6 6 3 TPR repeat TPR_2 PF07719.12 CCU98688.1 - 9.6e-22 75.1 21.7 0.0041 16.9 0.3 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 CCU98688.1 - 2.3e-18 64.4 6.0 0.0003 20.3 0.2 7.9 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCU98688.1 - 3.2e-12 46.2 26.2 7.1e-06 25.8 0.1 7.7 5 1 5 10 10 10 6 Tetratricopeptide repeat TPR_17 PF13431.1 CCU98688.1 - 4.1e-12 45.2 5.1 0.022 14.9 0.0 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCU98688.1 - 2e-11 43.4 30.5 0.015 15.8 0.2 10.3 7 2 4 11 11 10 4 Tetratricopeptide repeat Apc3 PF12895.2 CCU98688.1 - 6.8e-10 38.9 14.7 0.0039 17.3 0.5 4.8 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CCU98688.1 - 7.8e-10 37.8 22.0 0.021 14.5 0.0 8.1 7 1 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCU98688.1 - 1.2e-09 38.5 37.3 0.00018 22.1 1.1 8.2 6 2 3 9 9 8 5 Tetratricopeptide repeat APC8 PF04049.8 CCU98688.1 - 3.3e-08 33.3 0.0 1.9e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_9 PF13371.1 CCU98688.1 - 9.9e-08 31.7 23.5 3.5e-05 23.5 0.5 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 CCU98688.1 - 2e-05 23.8 12.0 0.0073 15.3 0.0 4.8 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCU98688.1 - 2.2e-05 24.6 22.6 0.22 11.8 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCU98688.1 - 0.00021 21.4 14.1 10 6.8 0.0 7.8 9 0 0 9 9 7 0 Tetratricopeptide repeat ChAPs PF09295.5 CCU98688.1 - 0.00047 19.0 0.1 0.0097 14.7 0.0 2.5 1 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_3 PF07720.7 CCU98688.1 - 0.17 11.7 9.2 5.3 6.9 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Aminotran_3 PF00202.16 CCU98690.1 - 7.2e-42 143.4 0.0 1.8e-20 73.0 0.0 2.7 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 CCU98690.1 - 4.4e-27 94.9 0.0 7.5e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mpp10 PF04006.7 CCU98691.1 - 5.4e-94 315.6 38.0 7.7e-94 315.1 26.3 1.1 1 0 0 1 1 1 1 Mpp10 protein BRO1 PF03097.13 CCU98692.1 - 0.12 11.1 0.1 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 BRO1-like domain Gcd10p PF04189.8 CCU98693.1 - 1.1e-74 251.3 0.0 7.6e-74 248.5 0.0 1.9 1 1 0 1 1 1 1 Gcd10p family PLDc_2 PF13091.1 CCU98695.1 - 1.3e-10 41.1 0.0 1.9e-05 24.4 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CCU98695.1 - 0.0001 22.0 4.1 0.26 11.1 0.1 3.1 2 1 0 2 2 2 2 Phospholipase D Active site motif Peptidase_M76 PF09768.4 CCU98698.1 - 1.5e-67 226.3 0.1 1.8e-67 226.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 CCU98698.1 - 0.019 14.6 3.2 0.028 14.0 1.2 1.8 1 1 1 2 2 2 0 SprT-like family Dicty_spore_N PF04562.7 CCU98698.1 - 0.37 11.0 4.2 2.1 8.6 0.2 2.7 2 1 1 3 3 3 0 Dictyostelium spore coat protein, N terminus Ribosomal_L13e PF01294.13 CCU98699.1 - 4.5e-60 202.1 7.4 6.3e-60 201.6 5.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e EVE PF01878.13 CCU98700.1 - 4.9e-37 127.1 0.0 9e-37 126.2 0.0 1.3 1 1 0 1 1 1 1 EVE domain OPT PF03169.10 CCU98702.1 - 2.1e-67 228.0 20.9 2.5e-67 227.7 14.5 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GP46 PF07409.7 CCU98702.1 - 0.083 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Phage protein GP46 DUF2427 PF10348.4 CCU98702.1 - 0.13 11.8 4.4 0.097 12.2 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) YbjM PF11045.3 CCU98702.1 - 0.31 10.8 3.2 1.5 8.5 0.1 2.5 2 0 0 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae MadM PF03818.8 CCU98702.1 - 0.35 10.4 8.3 5.7 6.5 0.0 3.5 3 0 0 3 3 3 0 Malonate/sodium symporter MadM subunit DUF997 PF06196.7 CCU98702.1 - 10 5.7 9.2 0.75 9.3 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF997) Metallophos PF00149.23 CCU98703.1 - 3.1e-09 36.5 2.8 5.7e-09 35.6 1.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCU98703.1 - 0.031 14.1 0.0 0.076 12.8 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain His_Phos_2 PF00328.17 CCU98704.1 - 4.8e-14 52.4 0.0 2e-13 50.3 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1154 PF06631.6 CCU98704.1 - 0.035 13.7 0.3 0.065 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) 2-Hacid_dh_C PF02826.14 CCU98705.1 - 3.3e-48 163.1 0.0 4.6e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCU98705.1 - 6.3e-19 67.7 0.0 8.4e-19 67.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCU98705.1 - 1.6e-05 24.8 0.0 6.1e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 CCU98705.1 - 0.0018 17.6 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_C PF03720.10 CCU98705.1 - 0.0025 17.9 0.0 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain MTS PF05175.9 CCU98705.1 - 0.06 12.7 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain WD40 PF00400.27 CCU98706.1 - 2.5e-44 147.6 7.1 2.5e-10 39.8 0.0 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 CCU98706.1 - 9.8e-13 47.0 2.0 0.00055 18.2 0.0 4.2 3 1 1 4 4 4 4 Nucleoporin Nup120/160 CAML PF14963.1 CCU98707.1 - 0.0037 16.6 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand DNA_topoisoIV PF00521.15 CCU98708.1 - 1.7e-122 409.3 0.0 2.7e-122 408.6 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CCU98708.1 - 2.1e-32 111.7 0.2 4.9e-32 110.5 0.2 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CCU98708.1 - 7.6e-13 48.2 0.0 2.1e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CCU98708.1 - 2e-08 33.9 0.0 7.3e-08 32.1 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ECH PF00378.15 CCU98709.1 - 2.9e-79 265.6 3.0 3.7e-79 265.3 2.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CCU98709.1 - 0.00011 21.9 0.5 0.013 15.3 0.0 2.6 2 1 0 2 2 2 2 Peptidase family S49 ECH_C PF13766.1 CCU98709.1 - 0.0031 17.6 0.2 0.0063 16.6 0.1 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region RRM_6 PF14259.1 CCU98710.1 - 0.0053 16.7 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCU98710.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1902 PF08972.6 CCU98710.1 - 0.034 13.7 1.3 0.093 12.3 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) RRM_5 PF13893.1 CCU98710.1 - 0.053 13.3 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phosphodiest PF01663.17 CCU98711.1 - 1.6e-11 44.1 0.1 2.4e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CCU98711.1 - 8.1e-06 25.3 0.3 1.4e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 CCU98711.1 - 0.047 12.8 0.1 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Sulfatase PCI PF01399.22 CCU98712.1 - 0.0028 17.9 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 PCI domain DNA_pol_E_B PF04042.11 CCU98713.1 - 8e-36 123.2 0.0 1.1e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dus PF01207.12 CCU98714.1 - 6.5e-50 169.7 0.0 1.8e-47 161.7 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 CCU98714.1 - 9.4e-06 25.1 8.6 0.0025 17.4 2.0 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ATP-synt_B PF00430.13 CCU98714.1 - 0.81 9.4 2.4 1.6 8.5 1.7 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) tRNA-synt_1g PF09334.6 CCU98715.1 - 7.7e-144 479.1 0.0 9.5e-144 478.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.15 CCU98715.1 - 2.7e-09 36.5 4.2 6.4e-09 35.3 2.9 1.7 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.17 CCU98715.1 - 1e-07 30.3 0.4 0.0002 19.4 0.0 2.9 3 2 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) DZR PF12773.2 CCU98715.1 - 0.14 11.9 10.6 0.51 10.1 5.0 2.3 1 1 1 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 CCU98715.1 - 2 8.2 8.4 1.3 8.8 1.2 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) cNMP_binding PF00027.24 CCU98716.1 - 1.2e-39 134.0 0.0 2.2e-16 59.4 0.0 4.6 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 CCU98716.1 - 3.8e-18 66.1 6.0 6.7e-12 45.7 2.3 3.0 3 0 0 3 3 3 2 Patatin-like phospholipase Gln-synt_C PF00120.19 CCU98717.1 - 6.7e-57 192.5 0.0 7.9e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CCU98717.1 - 9.5e-19 66.7 0.0 1.5e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain FAD_binding_2 PF00890.19 CCU98717.1 - 0.0036 16.1 0.1 0.0062 15.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain SMK-1 PF04802.10 CCU98718.1 - 2.3e-53 180.6 0.1 4e-53 179.8 0.1 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Rcd1 PF04078.8 CCU98718.1 - 0.0035 16.2 1.4 0.019 13.8 0.2 2.3 2 0 0 2 2 2 1 Cell differentiation family, Rcd1-like Arm_2 PF04826.8 CCU98718.1 - 0.0048 16.0 0.1 0.13 11.3 0.1 2.1 2 0 0 2 2 2 1 Armadillo-like YEATS PF03366.11 CCU98719.1 - 2.5e-31 107.2 0.0 4.1e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 YEATS family PPR_2 PF13041.1 CCU98720.1 - 2e-20 72.4 0.0 2.7e-06 27.2 0.0 6.8 6 2 3 9 9 9 3 PPR repeat family PPR_3 PF13812.1 CCU98720.1 - 3.2e-18 64.4 30.3 0.0059 16.8 0.0 12.4 13 0 0 13 13 13 6 Pentatricopeptide repeat domain PPR PF01535.15 CCU98720.1 - 2.8e-16 58.2 0.2 0.0084 16.0 0.0 9.5 11 0 0 11 11 11 2 PPR repeat PPR_1 PF12854.2 CCU98720.1 - 1.9e-10 40.0 0.0 0.014 14.8 0.0 5.7 6 0 0 6 6 6 3 PPR repeat TPR_10 PF13374.1 CCU98720.1 - 0.048 13.6 11.3 1.4 8.9 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCU98720.1 - 0.11 12.9 5.3 64 4.3 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCU98720.1 - 0.24 12.1 41.4 1.2 9.9 0.0 11.3 10 2 0 10 10 10 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCU98720.1 - 0.39 10.7 6.2 40 4.4 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DLIC PF05783.6 CCU98721.1 - 9.1e-18 64.1 0.0 3.7e-13 48.9 0.0 3.0 2 1 1 3 3 3 2 Dynein light intermediate chain (DLIC) AAA_25 PF13481.1 CCU98721.1 - 0.00068 19.0 0.3 0.0017 17.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CCU98721.1 - 0.00083 19.8 0.0 0.0042 17.5 0.0 2.2 2 1 0 2 2 1 1 Miro-like protein AAA_22 PF13401.1 CCU98721.1 - 0.0019 18.3 0.0 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCU98721.1 - 0.0019 18.0 4.0 0.012 15.4 0.2 3.5 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.1 CCU98721.1 - 0.0045 16.9 6.5 0.022 14.7 1.3 2.7 1 1 1 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CCU98721.1 - 0.0051 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 CCU98721.1 - 0.0071 15.4 0.1 0.074 12.1 0.0 2.3 3 0 0 3 3 3 1 Zeta toxin AAA_17 PF13207.1 CCU98721.1 - 0.0071 17.1 0.0 0.015 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CCU98721.1 - 0.0086 15.7 0.1 0.023 14.3 0.0 1.9 1 1 1 2 2 2 1 NACHT domain ABC_tran PF00005.22 CCU98721.1 - 0.0094 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter cobW PF02492.14 CCU98721.1 - 0.016 14.6 0.0 0.56 9.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CCU98721.1 - 0.017 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CCU98721.1 - 0.022 14.1 0.0 0.051 12.9 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 CCU98721.1 - 0.026 14.0 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 CCU98721.1 - 0.026 14.4 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 CCU98721.1 - 0.027 14.0 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 CCU98721.1 - 0.036 14.2 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 CCU98721.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 CCU98721.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 CCU98721.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 1 0 1 1 1 0 NTPase DUF258 PF03193.11 CCU98721.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Voltage_CLC PF00654.15 CCU98722.1 - 1.2e-79 267.8 29.2 1.1e-78 264.7 20.2 2.2 1 1 0 1 1 1 1 Voltage gated chloride channel SAC3_GANP PF03399.11 CCU98722.1 - 3.3e-49 167.2 0.0 6.9e-49 166.1 0.0 1.6 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family CBS PF00571.23 CCU98722.1 - 3.1e-07 30.0 0.4 8.2e-05 22.3 0.0 3.9 4 0 0 4 4 4 1 CBS domain CHD5 PF04420.9 CCU98724.1 - 3.6e-13 49.4 11.0 3.6e-12 46.2 2.6 2.1 1 1 1 2 2 2 2 CHD5-like protein Ribosomal_L29 PF00831.18 CCU98724.1 - 0.02 14.5 0.5 0.033 13.8 0.3 1.3 1 0 0 1 1 1 0 Ribosomal L29 protein DASH_Hsk3 PF08227.6 CCU98724.1 - 0.024 14.8 0.1 0.037 14.2 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like DUF106 PF01956.11 CCU98724.1 - 0.027 13.9 0.2 0.035 13.6 0.1 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 MbeD_MobD PF04899.7 CCU98724.1 - 0.039 13.8 0.6 0.065 13.1 0.4 1.3 1 0 0 1 1 1 0 MbeD/MobD like SCP2 PF02036.12 CCU98725.1 - 2.1e-05 24.7 0.0 3.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 CCU98725.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal TPR_MLP1_2 PF07926.7 CCU98726.1 - 2e-05 24.3 22.3 2e-05 24.3 15.5 14.1 8 4 2 11 11 11 5 TPR/MLP1/MLP2-like protein Filament PF00038.16 CCU98726.1 - 0.0058 16.1 6.6 0.0058 16.1 4.6 11.1 5 3 5 10 10 10 3 Intermediate filament protein ThiF PF00899.16 CCU98728.1 - 6.9e-16 58.3 0.1 1.1e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family zf-DHHC PF01529.15 CCU98729.1 - 2.3e-30 105.2 5.6 4e-30 104.4 3.9 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF1069 PF06370.6 CCU98729.1 - 0.016 14.5 0.1 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) AAA_23 PF13476.1 CCU98730.1 - 3.5e-22 79.7 5.5 5.8e-21 75.7 1.7 4.0 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 CCU98730.1 - 5.8e-13 48.5 0.0 3.2e-12 46.1 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CCU98730.1 - 8.7e-09 35.1 0.1 5e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 CCU98730.1 - 6.4e-06 26.3 0.0 0.0018 18.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CCU98730.1 - 8.7e-05 21.7 0.0 0.00049 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.1 CCU98730.1 - 0.00012 20.6 0.0 0.00012 20.6 0.0 4.9 2 1 4 6 6 6 2 AAA domain DUF3584 PF12128.3 CCU98730.1 - 0.00069 17.1 14.3 0.00069 17.1 9.9 5.5 3 2 1 5 5 5 1 Protein of unknown function (DUF3584) AAA_29 PF13555.1 CCU98730.1 - 0.0033 16.9 0.0 0.007 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CCU98730.1 - 0.025 14.8 0.0 0.025 14.8 0.0 5.2 6 2 0 6 6 6 0 ABC transporter GTP_EFTU PF00009.22 CCU98730.1 - 0.029 13.8 2.8 0.92 8.9 0.1 2.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ish1 PF10281.4 CCU98731.1 - 4e-39 132.2 17.8 5.9e-07 29.4 0.3 6.6 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein HeH PF12949.2 CCU98731.1 - 5.9e-07 28.9 0.1 0.02 14.4 0.0 5.2 5 0 0 5 5 5 1 HeH/LEM domain SAP PF02037.22 CCU98731.1 - 0.0029 17.0 0.0 1.1 8.8 0.0 3.9 4 0 0 4 4 4 1 SAP domain HTH_29 PF13551.1 CCU98731.1 - 0.02 15.0 1.5 0.44 10.7 0.3 3.1 2 2 2 4 4 4 0 Winged helix-turn helix DUF4253 PF14062.1 CCU98731.1 - 0.037 13.6 0.0 17 5.0 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4253) DUF2385 PF09539.5 CCU98731.1 - 0.094 13.1 0.4 0.45 10.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) SAM_2 PF07647.12 CCU98731.1 - 0.57 10.0 2.8 9 6.2 0.1 3.2 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) 6PGD PF00393.14 CCU98731.1 - 1.1 8.4 7.3 1.2 8.2 2.2 2.8 2 1 1 3 3 3 0 6-phosphogluconate dehydrogenase, C-terminal domain F-box-like PF12937.2 CCU98733.1 - 2.2e-13 49.7 2.2 6.7e-13 48.1 1.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCU98733.1 - 3.9e-09 35.9 0.4 1.5e-08 34.0 0.3 2.0 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.1 CCU98733.1 - 0.00028 20.4 0.5 0.00076 19.0 0.0 2.0 2 0 0 2 2 2 1 TPR repeat SAP30_Sin3_bdg PF13867.1 CCU98733.1 - 0.086 12.7 0.4 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 TPR_14 PF13428.1 CCU98733.1 - 0.26 12.0 0.1 0.26 12.0 0.1 5.5 6 1 1 7 7 7 0 Tetratricopeptide repeat XPG_I PF00867.13 CCU98734.1 - 2.3e-11 43.6 0.0 7.1e-11 42.0 0.0 1.9 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CCU98734.1 - 3.3e-06 27.2 0.0 8.4e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain BP28CT PF08146.7 CCU98735.1 - 1.1e-22 80.4 0.0 3e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 CCU98735.1 - 6e-15 55.2 0.8 6e-15 55.2 0.6 6.0 4 3 1 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 CCU98735.1 - 0.092 12.8 9.7 0.035 14.1 0.3 5.0 3 0 0 3 3 3 0 HEAT repeat PHD PF00628.24 CCU98736.1 - 9.1e-07 28.4 19.8 1.5e-06 27.7 13.8 1.4 1 0 0 1 1 1 1 PHD-finger PQQ PF01011.16 CCU98737.1 - 4.1e-08 32.3 0.0 0.017 14.6 0.0 3.0 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.1 CCU98737.1 - 0.00012 21.5 0.0 0.17 11.3 0.0 2.7 3 0 0 3 3 3 2 PQQ-like domain CPSF100_C PF13299.1 CCU98738.1 - 1.6e-25 90.1 0.1 5e-21 75.5 0.0 3.2 2 1 1 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 CCU98738.1 - 1e-20 73.9 0.0 2e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 CCU98738.1 - 0.091 12.5 0.1 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase Ribosomal_L3 PF00297.17 CCU98739.1 - 4.6e-40 137.6 0.2 8e-40 136.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L3 DSPc PF00782.15 CCU98740.1 - 2.9e-32 111.0 0.0 1.6e-24 85.9 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCU98740.1 - 0.0042 16.4 0.0 0.0094 15.3 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase F-box PF00646.28 CCU98741.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 F-box domain Cpn60_TCP1 PF00118.19 CCU98742.1 - 7.3e-141 470.0 1.5 8.5e-141 469.8 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family G_glu_transpept PF01019.16 CCU98743.1 - 1.9e-137 458.8 0.0 2.4e-137 458.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Atg14 PF10186.4 CCU98744.1 - 0.0056 15.6 19.9 0.65 8.8 11.5 2.1 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 CCU98744.1 - 0.011 15.7 2.1 0.011 15.7 1.4 3.9 4 1 0 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit ATG16 PF08614.6 CCU98744.1 - 0.029 14.2 0.8 0.029 14.2 0.5 3.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Filament PF00038.16 CCU98744.1 - 0.03 13.7 23.1 0.11 11.9 9.6 2.3 2 0 0 2 2 2 0 Intermediate filament protein Lebercilin PF15619.1 CCU98744.1 - 0.18 11.1 27.8 0.88 8.9 14.9 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.5 CCU98744.1 - 0.3 11.1 10.8 0.81 9.8 3.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 CCU98744.1 - 0.6 8.4 10.0 0.72 8.2 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) MscS_porin PF12795.2 CCU98744.1 - 2 7.6 39.2 0.28 10.4 2.4 3.4 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain IncA PF04156.9 CCU98744.1 - 2.2 7.8 35.1 0.05 13.1 0.6 2.8 2 1 0 2 2 2 0 IncA protein Spc7 PF08317.6 CCU98744.1 - 2.5 6.6 22.2 0.72 8.4 1.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Mnd1 PF03962.10 CCU98744.1 - 6.9 6.2 30.7 1.1 8.9 1.0 3.2 2 1 1 3 3 3 0 Mnd1 family Rab5-bind PF09311.6 CCU98744.1 - 8.3 6.2 33.6 0.14 12.0 0.9 3.0 3 0 0 3 3 3 0 Rabaptin-like protein NGP1NT PF08153.7 CCU98745.1 - 1.1e-42 145.0 0.0 1.1e-42 145.0 0.0 1.8 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CCU98745.1 - 6.3e-20 71.2 0.0 8.1e-16 58.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCU98745.1 - 1.5e-06 27.5 0.1 1e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B TFIIA PF03153.8 CCU98745.1 - 0.00015 21.8 17.0 0.00015 21.8 11.8 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF258 PF03193.11 CCU98745.1 - 0.00016 20.8 0.0 0.0003 19.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 CCU98745.1 - 0.00065 18.9 0.1 0.1 11.8 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF2457 PF10446.4 CCU98745.1 - 0.0011 17.7 36.6 0.0021 16.8 25.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) GTP_EFTU PF00009.22 CCU98745.1 - 0.0028 17.1 0.1 0.42 10.0 0.0 2.9 1 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Nop14 PF04147.7 CCU98745.1 - 0.011 13.6 36.0 0.015 13.2 25.0 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CCU98745.1 - 0.083 11.3 37.4 0.12 10.8 25.9 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 CCU98745.1 - 0.36 10.0 36.5 0.74 9.0 25.3 1.4 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.6 CCU98745.1 - 5.6 4.9 19.4 8.8 4.2 13.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Dynamin_N PF00350.18 CCU98745.1 - 7.2 6.4 0.0 1.3 8.7 0.0 4.7 4 2 1 5 5 4 0 Dynamin family tRNA-synt_1d PF00750.14 CCU98746.1 - 2.2e-87 293.1 0.0 2.8e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CCU98746.1 - 6.4e-19 68.0 0.0 1.5e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain AAA_13 PF13166.1 CCU98747.1 - 0.46 8.8 3.2 0.61 8.4 2.2 1.1 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 CCU98747.1 - 2.9 7.6 19.3 0.24 11.1 5.7 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 CCU98747.1 - 6.9 6.0 6.5 20 4.5 1.4 2.6 1 1 0 2 2 2 0 Phage minor structural protein GP20 VHS PF00790.14 CCU98749.1 - 6.1e-37 126.3 0.0 6e-36 123.1 0.0 2.3 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 CCU98749.1 - 5.5e-19 68.0 0.4 1.5e-18 66.6 0.1 1.8 2 0 0 2 2 2 1 GAT domain CDC37_N PF03234.9 CCU98749.1 - 0.53 10.5 2.5 0.83 9.9 1.7 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding PPR_2 PF13041.1 CCU98750.1 - 6e-10 38.9 0.0 0.042 13.8 0.0 5.2 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.1 CCU98750.1 - 6.6e-09 35.3 16.7 0.47 10.8 0.1 8.8 9 0 0 9 9 9 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 CCU98750.1 - 6.8e-05 22.2 0.0 0.02 14.3 0.0 4.0 5 1 0 5 5 5 1 PPR repeat PPR PF01535.15 CCU98750.1 - 0.00014 21.5 0.1 1.7 8.8 0.0 5.1 5 0 0 5 5 5 1 PPR repeat PIP5K PF01504.13 CCU98751.1 - 3.5e-62 209.7 0.0 6.7e-62 208.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CCU98751.1 - 2.2e-18 66.1 0.0 3.3e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 CCU98751.1 - 2.8e-17 62.3 9.7 8.6e-17 60.8 6.7 1.9 1 0 0 1 1 1 1 FYVE zinc finger AAA PF00004.24 CCU98752.1 - 3.6e-43 146.9 0.0 6e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCU98752.1 - 1e-07 31.7 0.1 4.4e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCU98752.1 - 1e-07 32.1 0.0 5.2e-06 26.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCU98752.1 - 9.4e-07 29.0 0.0 0.00074 19.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 CCU98752.1 - 4.4e-06 26.7 0.0 9.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CCU98752.1 - 3.3e-05 23.0 0.0 6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCU98752.1 - 4.7e-05 23.0 0.2 0.00015 21.4 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CCU98752.1 - 0.0011 19.8 0.2 0.0031 18.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 CCU98752.1 - 0.0011 17.7 0.0 0.0019 16.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 CCU98752.1 - 0.0013 18.2 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.8 CCU98752.1 - 0.0014 17.6 0.0 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 CCU98752.1 - 0.002 17.2 0.0 0.0042 16.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 CCU98752.1 - 0.0027 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CCU98752.1 - 0.0031 16.6 0.0 0.0058 15.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CCU98752.1 - 0.0047 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCU98752.1 - 0.0049 16.4 0.2 0.022 14.3 0.0 2.1 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 CCU98752.1 - 0.0052 16.9 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 CCU98752.1 - 0.0054 16.6 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CCU98752.1 - 0.0072 15.8 0.1 0.03 13.7 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 CCU98752.1 - 0.0089 16.3 0.2 0.042 14.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain PhoH PF02562.11 CCU98752.1 - 0.009 15.2 0.2 0.02 14.1 0.1 1.6 1 1 0 1 1 1 1 PhoH-like protein AAA_24 PF13479.1 CCU98752.1 - 0.01 15.4 0.2 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CCU98752.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CCU98752.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 CCU98752.1 - 0.024 13.7 0.1 0.06 12.4 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 CCU98752.1 - 0.028 13.8 0.2 0.098 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CCU98752.1 - 0.035 13.8 0.0 0.25 11.0 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase NACHT PF05729.7 CCU98752.1 - 0.043 13.4 0.0 0.15 11.6 0.0 1.9 1 1 1 2 2 2 0 NACHT domain AAA_23 PF13476.1 CCU98752.1 - 0.05 13.9 1.7 7.9 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 CCU98752.1 - 0.069 12.0 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 CCU98752.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 CCU98752.1 - 0.16 11.4 0.2 0.48 9.9 0.0 1.9 2 1 0 2 2 1 0 AAA domain Clathrin PF00637.15 CCU98753.1 - 3.6e-202 662.0 25.9 7.9e-32 109.8 0.4 7.6 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CCU98753.1 - 3e-31 107.1 0.1 1.1e-30 105.2 0.1 2.1 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 CCU98753.1 - 1.4e-22 78.3 0.0 0.035 14.3 0.0 7.7 7 0 0 7 7 7 5 Clathrin propeller repeat Clathrin-link PF09268.5 CCU98753.1 - 1.9e-10 39.5 1.0 4.3e-10 38.4 0.0 2.2 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 CCU98753.1 - 1e-06 27.8 1.7 0.12 11.1 0.0 3.9 4 0 0 4 4 4 2 Coatomer WD associated region TPR_1 PF00515.23 CCU98753.1 - 1e-05 24.8 3.8 13 5.5 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCU98753.1 - 0.0037 17.0 8.4 26 5.0 0.0 7.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCU98753.1 - 0.0076 16.1 12.2 3.7 7.5 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCU98753.1 - 0.036 13.8 9.4 5.6 7.0 0.1 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat PX PF00787.19 CCU98754.1 - 5.7e-21 74.4 0.1 1.6e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CCU98754.1 - 8.1e-07 28.5 6.0 0.0012 18.1 0.5 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 CCU98754.1 - 0.0021 17.5 4.3 0.0096 15.4 3.0 2.0 1 1 0 1 1 1 1 BAR domain IncA PF04156.9 CCU98754.1 - 0.019 14.5 4.7 0.6 9.6 0.1 2.2 2 0 0 2 2 2 0 IncA protein RNA_capsid PF03035.9 CCU98754.1 - 0.042 13.6 0.1 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein Fis1_TPR_N PF14852.1 CCU98755.1 - 1.2e-15 56.4 0.0 2.3e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCU98755.1 - 3.7e-10 39.5 0.6 6.3e-10 38.7 0.4 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 CCU98755.1 - 0.011 15.5 0.8 0.03 14.2 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCU98755.1 - 0.11 13.2 0.1 0.22 12.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2376 PF09550.5 CCU98755.1 - 0.17 12.0 0.4 7 6.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical phage protein (DUF2376) zf-C3HC4_3 PF13920.1 CCU98756.1 - 1.6e-08 34.0 18.9 2.8e-06 26.8 5.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCU98756.1 - 8.2e-08 32.1 22.4 0.00019 21.3 2.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCU98756.1 - 9.2e-07 28.6 21.1 0.0037 17.0 7.3 2.6 2 0 0 2 2 2 2 Ring finger domain FYVE PF01363.16 CCU98756.1 - 2.9e-06 27.0 5.2 2.9e-06 27.0 3.6 2.8 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4 PF00097.20 CCU98756.1 - 1.4e-05 24.6 23.5 0.0043 16.6 7.8 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 CCU98756.1 - 1.6e-05 24.2 18.2 3.9e-05 22.9 0.5 3.0 1 1 1 3 3 3 2 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 CCU98756.1 - 0.00024 20.8 18.8 0.016 15.0 0.9 3.4 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCU98756.1 - 0.00027 20.6 25.8 0.0011 18.6 8.0 3.7 2 2 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CCU98756.1 - 0.0047 16.6 15.5 0.015 15.0 4.8 2.6 2 0 0 2 2 2 2 RING-type zinc-finger Atg14 PF10186.4 CCU98756.1 - 0.014 14.4 5.5 0.026 13.4 3.8 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-CHY PF05495.7 CCU98756.1 - 0.81 9.8 15.5 5.9 7.1 4.9 3.0 2 1 1 3 3 3 0 CHY zinc finger zf-RING_4 PF14570.1 CCU98756.1 - 1.4 8.5 17.7 0.78 9.3 0.4 3.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 CCU98756.1 - 9.1 5.9 21.8 5.2 6.7 9.1 3.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 ETC_C1_NDUFA5 PF04716.9 CCU98757.1 - 4.6e-15 54.8 0.1 6.8e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region INTS5_N PF14837.1 CCU98757.1 - 0.043 13.2 0.1 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus Sds3 PF08598.6 CCU98758.1 - 4.7e-10 39.3 0.3 5.9e-10 39.0 0.2 1.2 1 0 0 1 1 1 1 Sds3-like Orn_Arg_deC_N PF02784.11 CCU98759.1 - 7.5e-71 238.2 0.0 1e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CCU98759.1 - 1.1e-29 102.5 0.0 1.6e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain B12-binding PF02310.14 CCU98759.1 - 0.13 12.1 0.0 0.4 10.5 0.0 2.0 1 1 0 1 1 1 0 B12 binding domain Zn_clus PF00172.13 CCU98760.1 - 1.9e-05 24.4 7.8 1.9e-05 24.4 5.4 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 CCU98761.1 - 2.3e-63 213.7 0.0 6.4e-63 212.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98761.1 - 8.6e-33 113.4 0.0 2.1e-32 112.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pentapeptide_4 PF13599.1 CCU98761.1 - 6.9e-05 22.5 0.0 0.31 10.8 0.0 2.7 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) APH PF01636.18 CCU98761.1 - 0.014 15.1 0.0 0.014 15.1 0.0 3.6 3 1 0 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCU98761.1 - 0.13 11.8 0.0 0.13 11.8 0.0 3.0 2 1 0 2 2 2 0 Choline/ethanolamine kinase Complex1_LYR_1 PF13232.1 CCU98762.1 - 1.5e-08 34.7 5.8 4.7e-08 33.1 4.1 1.9 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CCU98762.1 - 0.0011 18.6 7.1 0.0029 17.3 5.0 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) UPRTase PF14681.1 CCU98763.1 - 1.3e-49 168.2 0.0 1.6e-25 89.5 0.0 2.1 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Rxt3 PF08642.5 CCU98764.1 - 3.9e-20 72.2 0.0 1e-19 70.8 0.0 1.7 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 CCU98764.1 - 0.0036 17.2 0.0 0.041 13.8 0.0 2.1 2 0 0 2 2 2 1 LCCL domain ESCRT-II PF05871.7 CCU98765.1 - 1.3e-35 122.2 0.0 2.7e-35 121.2 0.0 1.4 1 1 0 1 1 1 1 ESCRT-II complex subunit WD40 PF00400.27 CCU98766.1 - 6.8e-29 98.6 3.6 1.4e-09 37.4 0.1 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCU98766.1 - 0.0045 16.7 0.0 1.4 8.7 0.0 3.0 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region TPT PF03151.11 CCU98768.1 - 0.02 14.5 1.1 0.023 14.3 0.7 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family UAA PF08449.6 CCU98768.1 - 0.044 12.7 0.1 0.051 12.4 0.1 1.0 1 0 0 1 1 1 0 UAA transporter family Sugar_transport PF06800.7 CCU98768.1 - 0.051 12.6 0.0 0.055 12.5 0.0 1.0 1 0 0 1 1 1 0 Sugar transport protein UAA PF08449.6 CCU98769.1 - 1.1e-06 27.8 11.9 2.2e-06 26.8 8.2 1.5 1 1 0 1 1 1 1 UAA transporter family Rhomboid PF01694.17 CCU98769.1 - 1.2 9.1 10.3 0.53 10.2 0.2 3.1 2 1 1 3 3 3 0 Rhomboid family NMO PF03060.10 CCU98770.1 - 1.3e-52 179.0 2.4 3e-52 177.8 1.7 1.6 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CCU98770.1 - 4e-07 29.2 0.0 0.018 13.9 0.0 2.6 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CCU98770.1 - 1.1e-05 24.4 0.5 2e-05 23.6 0.3 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 CCU98770.1 - 0.11 11.4 1.1 0.21 10.4 0.7 1.4 1 1 0 1 1 1 0 Conserved region in glutamate synthase ABC_membrane_2 PF06472.10 CCU98771.1 - 1.1e-93 313.4 5.0 1.4e-93 313.1 3.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CCU98771.1 - 2.1e-15 57.2 0.0 5.3e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.7 CCU98771.1 - 0.056 12.4 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CCU98771.1 - 0.096 13.5 0.0 0.35 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CCU98771.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PH PF00169.24 CCU98772.1 - 0.091 12.9 0.0 0.82 9.9 0.0 2.3 2 0 0 2 2 2 0 PH domain DUF4122 PF13498.1 CCU98772.1 - 0.42 9.9 0.0 0.86 8.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) SKI PF01202.17 CCU98773.1 - 7.6e-12 45.3 0.1 2.1e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.1 CCU98773.1 - 1.2e-08 34.9 0.2 5.1e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCU98773.1 - 3.5e-05 24.5 0.0 7.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CCU98773.1 - 0.0056 16.3 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase CPT PF07931.7 CCU98773.1 - 0.032 13.8 0.1 0.083 12.5 0.1 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zn_clus PF00172.13 CCU98774.1 - 6.9e-09 35.4 9.1 1.2e-08 34.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L23 PF00276.15 CCU98776.1 - 5.1e-05 23.1 0.0 9.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 DUF2459 PF09601.5 CCU98776.1 - 0.036 13.7 0.5 0.073 12.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) NIF PF03031.13 CCU98777.1 - 1.2e-48 164.7 0.0 3.9e-48 163.1 0.0 1.7 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.7 CCU98777.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Pkinase PF00069.20 CCU98778.1 - 2.1e-57 194.2 0.0 2.9e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98778.1 - 8.7e-29 100.3 0.0 1.4e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU98778.1 - 4e-06 26.0 0.0 7.7e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CCU98778.1 - 0.27 10.0 0.0 0.44 9.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2340 PF10209.4 CCU98779.1 - 1.5e-42 144.6 0.0 1.8e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) PXA PF02194.10 CCU98780.1 - 4e-12 46.0 0.0 8.2e-06 25.5 0.0 2.4 1 1 1 2 2 2 2 PXA domain Nexin_C PF08628.7 CCU98780.1 - 2.8e-05 24.1 0.0 0.00015 21.8 0.0 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 CCU98780.1 - 0.032 14.0 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 PX domain HSBP1 PF06825.7 CCU98780.1 - 0.19 11.3 0.0 0.47 10.0 0.0 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 XPG_N PF00752.12 CCU98781.1 - 1e-29 102.7 0.0 1.9e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCU98781.1 - 5.6e-25 87.2 0.0 1.2e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 CCU98781.1 - 1.2e-06 28.2 0.0 4e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 XPG domain containing Sec5 PF15469.1 CCU98781.1 - 0.00063 19.5 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 DUF4446 PF14584.1 CCU98781.1 - 9.7 6.0 5.9 2.7 7.7 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) NDUF_B8 PF05821.6 CCU98782.1 - 2.2e-05 24.2 0.1 3.3e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Pex14_N PF04695.8 CCU98782.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Metallophos PF00149.23 CCU98783.1 - 6e-44 149.8 1.3 7.8e-44 149.4 0.9 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Homez PF11569.3 CCU98783.1 - 0.069 12.2 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MCM PF00493.18 CCU98784.1 - 3.8e-139 463.1 0.0 5.6e-139 462.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 CCU98784.1 - 2.1e-22 79.8 12.3 2.1e-22 79.8 8.5 2.4 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 CCU98784.1 - 9.6e-20 71.2 0.1 2e-17 63.8 0.0 2.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCU98784.1 - 2.8e-08 33.1 0.0 8.9e-07 28.2 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCU98784.1 - 3.3e-06 26.8 0.0 6.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCU98784.1 - 0.0012 18.4 0.0 0.0075 15.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCU98784.1 - 0.012 15.0 0.0 0.16 11.4 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain DNA_gyraseB_C PF00986.16 CCU98784.1 - 0.058 13.1 0.7 4.4 7.1 0.0 3.0 3 0 0 3 3 3 0 DNA gyrase B subunit, carboxyl terminus DUF1931 PF09123.6 CCU98784.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) AAA PF00004.24 CCU98784.1 - 0.087 13.0 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn_ribbon_2 PF12674.2 CCU98784.1 - 0.28 11.5 0.3 0.72 10.2 0.2 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain UQ_con PF00179.21 CCU98785.1 - 5.6e-08 32.3 3.3 5.6e-08 32.3 2.3 2.5 2 1 0 2 2 2 1 Ubiquitin-conjugating enzyme Csm1 PF12539.3 CCU98786.1 - 1.1e-06 29.0 0.0 1.8e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Myosin_tail_1 PF01576.14 CCU98786.1 - 0.00039 18.2 2.8 0.00051 17.9 1.9 1.1 1 0 0 1 1 1 1 Myosin tail Cortex-I_coil PF09304.5 CCU98786.1 - 0.0065 16.4 2.7 0.026 14.5 1.8 1.9 2 0 0 2 2 2 1 Cortexillin I, coiled coil SKIP_SNW PF02731.10 CCU98786.1 - 0.12 11.8 2.1 0.18 11.2 1.5 1.2 1 0 0 1 1 1 0 SKIP/SNW domain ABC2_membrane PF01061.19 CCU98787.1 - 8.5e-241 792.8 169.1 1.8e-43 148.1 9.2 7.0 7 0 0 7 7 6 6 ABC-2 type transporter ABC_tran PF00005.22 CCU98787.1 - 6e-118 389.3 0.0 5e-18 65.7 0.0 8.4 9 0 0 9 9 8 6 ABC transporter PDR_CDR PF06422.7 CCU98787.1 - 4.9e-68 225.2 24.5 2.7e-22 78.3 0.0 7.8 8 0 0 8 8 7 3 CDR ABC transporter ABC_trans_N PF14510.1 CCU98787.1 - 1e-30 105.6 0.1 2e-11 43.7 0.0 3.7 3 0 0 3 3 3 3 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CCU98787.1 - 1e-22 80.5 1.3 0.00025 20.5 0.0 7.0 6 0 0 6 6 6 3 AAA domain ABC2_membrane_3 PF12698.2 CCU98787.1 - 4.2e-20 72.0 121.3 3.2e-06 26.4 5.0 7.6 6 2 0 6 6 6 6 ABC-2 family transporter protein DUF258 PF03193.11 CCU98787.1 - 1.5e-18 66.4 0.2 8.7e-05 21.7 0.0 4.0 4 0 0 4 4 3 3 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCU98787.1 - 6.9e-17 61.8 0.2 0.064 13.4 0.0 7.2 6 1 0 6 6 6 3 AAA domain cobW PF02492.14 CCU98787.1 - 9.4e-15 54.4 8.7 0.0037 16.7 0.0 5.8 6 0 0 6 6 6 3 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 CCU98787.1 - 1.3e-12 48.1 12.0 0.03 14.3 0.0 6.4 6 0 0 6 6 6 3 AAA ATPase domain AAA_17 PF13207.1 CCU98787.1 - 3.4e-12 47.2 0.0 0.76 10.6 0.0 6.4 6 0 0 6 6 6 3 AAA domain AAA_18 PF13238.1 CCU98787.1 - 1e-11 45.2 0.1 0.68 10.2 0.0 6.3 6 0 0 6 6 6 3 AAA domain AAA_21 PF13304.1 CCU98787.1 - 1.9e-11 44.5 0.0 2.2 8.1 0.0 7.3 7 0 0 7 7 7 2 AAA domain UPF0079 PF02367.12 CCU98787.1 - 6e-11 42.0 11.6 0.16 11.5 0.1 6.5 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CCU98787.1 - 6.3e-11 42.2 4.1 0.63 9.6 0.0 6.4 6 0 0 6 6 6 3 NACHT domain AAA_29 PF13555.1 CCU98787.1 - 1.6e-10 40.3 11.8 0.053 13.0 0.1 6.2 6 0 0 6 6 6 3 P-loop containing region of AAA domain AAA_19 PF13245.1 CCU98787.1 - 2.1e-10 40.1 7.3 2.7 7.7 0.0 6.7 6 0 0 6 6 6 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 CCU98787.1 - 3.4e-10 39.7 8.2 3.2 7.1 0.0 8.2 8 0 0 8 8 8 0 FtsK/SpoIIIE family SMC_N PF02463.14 CCU98787.1 - 2.5e-08 33.4 0.0 1.5 7.9 0.0 6.2 7 0 0 7 7 7 3 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 CCU98787.1 - 1.2e-07 31.7 0.5 4.4 7.1 0.0 6.1 6 0 0 6 6 6 0 AAA domain MMR_HSR1 PF01926.18 CCU98787.1 - 1.6e-06 28.0 3.8 3.2 7.7 0.0 5.6 6 0 0 6 6 5 0 50S ribosome-binding GTPase AAA_10 PF12846.2 CCU98787.1 - 1.7e-06 27.7 0.3 7.6 5.8 0.0 6.3 7 0 0 7 7 7 0 AAA-like domain AAA PF00004.24 CCU98787.1 - 3.4e-06 27.3 2.9 17 5.6 0.0 6.3 6 0 0 6 6 6 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 CCU98787.1 - 3.5e-06 27.4 0.4 24 5.4 0.0 6.0 6 0 0 6 6 5 0 Miro-like protein AAA_15 PF13175.1 CCU98787.1 - 5.6e-06 25.6 0.0 11 4.9 0.0 5.5 6 0 0 6 6 6 0 AAA ATPase domain AAA_23 PF13476.1 CCU98787.1 - 5.9e-06 26.7 1.6 3.5 7.8 0.0 3.9 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 CCU98787.1 - 8.3e-06 25.6 0.1 11 6.0 0.0 5.4 4 0 0 4 4 4 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 CCU98787.1 - 1.1e-05 25.4 7.9 4 7.3 0.0 5.7 6 0 0 6 6 6 0 AAA domain Fcf2 PF08698.6 CCU98787.1 - 1.3e-05 25.1 0.3 0.024 14.6 0.0 2.9 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing T2SE PF00437.15 CCU98787.1 - 2.2e-05 23.4 1.5 12 4.6 0.0 5.6 6 0 0 6 6 6 0 Type II/IV secretion system protein PduV-EutP PF10662.4 CCU98787.1 - 3.3e-05 23.3 6.8 3.9 6.9 0.1 5.3 6 0 0 6 6 5 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CCU98787.1 - 4.1e-05 23.7 0.2 15 5.7 0.0 4.9 5 0 0 5 5 3 0 RNA helicase Zeta_toxin PF06414.7 CCU98787.1 - 0.0001 21.5 0.1 5 6.1 0.0 3.9 3 0 0 3 3 3 0 Zeta toxin Septin PF00735.13 CCU98787.1 - 0.00011 21.3 0.5 11 4.8 0.0 4.6 5 0 0 5 5 5 0 Septin Arch_ATPase PF01637.13 CCU98787.1 - 0.00026 20.7 0.0 57 3.2 0.0 5.6 6 0 0 6 6 6 0 Archaeal ATPase AAA_30 PF13604.1 CCU98787.1 - 0.00026 20.6 7.4 10 5.6 0.1 5.6 6 0 0 6 6 6 0 AAA domain SKI PF01202.17 CCU98787.1 - 0.011 15.6 0.1 38 4.1 0.0 3.5 3 0 0 3 3 3 0 Shikimate kinase AAA_24 PF13479.1 CCU98787.1 - 0.011 15.3 8.2 36 3.8 0.0 5.9 6 0 0 6 6 6 0 AAA domain Dynamin_N PF00350.18 CCU98787.1 - 0.011 15.5 0.0 34 4.1 0.0 3.6 3 0 0 3 3 3 0 Dynamin family NTPase_1 PF03266.10 CCU98787.1 - 0.013 15.2 2.1 57 3.3 0.0 5.0 6 0 0 6 6 4 0 NTPase GvpD PF07088.6 CCU98787.1 - 0.015 13.6 0.1 9.9 4.3 0.0 3.3 3 0 0 3 3 3 0 GvpD gas vesicle protein SPATA19 PF15212.1 CCU98787.1 - 0.087 12.8 0.0 74 3.4 0.0 3.3 3 0 0 3 3 3 0 Spermatogenesis-associated protein 19, mitochondrial FeoB_N PF02421.13 CCU98787.1 - 0.096 11.9 2.3 49 3.1 0.0 3.7 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_5 PF07728.9 CCU98787.1 - 0.097 12.3 6.2 64 3.2 0.0 5.1 6 0 0 6 6 4 0 AAA domain (dynein-related subfamily) Herpes_Helicase PF02689.9 CCU98787.1 - 0.099 10.3 0.0 15 3.1 0.0 2.8 3 0 0 3 3 3 0 Helicase ABC_ATPase PF09818.4 CCU98787.1 - 0.14 10.7 4.2 18 3.7 0.1 3.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class RuvB_N PF05496.7 CCU98787.1 - 0.18 10.8 3.9 36 3.2 0.1 3.6 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus ATP_bind_1 PF03029.12 CCU98787.1 - 0.23 10.9 4.7 49 3.3 0.0 5.3 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein DUF3080 PF11279.3 CCU98787.1 - 0.26 10.3 1.9 75 2.3 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3080) MobB PF03205.9 CCU98787.1 - 0.46 10.1 5.4 1.1e+02 2.4 0.1 4.8 6 0 0 6 6 4 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 CCU98787.1 - 0.9 9.3 4.7 81 2.9 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 Pox_A32 PF04665.7 CCU98787.1 - 1.2 8.4 8.7 62 2.7 0.0 4.9 6 0 0 6 6 5 0 Poxvirus A32 protein NTPase_P4 PF11602.3 CCU98787.1 - 3.4 6.5 4.0 88 1.9 0.1 3.1 3 0 0 3 3 3 0 ATPase P4 of dsRNA bacteriophage phi-12 ArgK PF03308.11 CCU98787.1 - 8.9 4.9 4.0 86 1.7 0.1 3.5 4 0 0 4 4 4 0 ArgK protein UDP-g_GGTase PF06427.6 CCU98788.1 - 1.5e-40 138.7 0.0 3.1e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 CCU98788.1 - 2.4e-07 30.3 0.0 6.8e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 8 5_nucleotid_C PF02872.13 CCU98789.1 - 2.3e-29 102.3 0.0 3.1e-28 98.7 0.0 2.1 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain HMG_box_2 PF09011.5 CCU98790.1 - 1.2e-13 51.2 14.2 3.9e-10 39.9 4.1 2.2 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 CCU98790.1 - 1.8e-12 47.3 19.9 3.3e-08 33.6 4.3 3.1 2 1 0 2 2 2 2 HMG (high mobility group) box DUF1413 PF07205.6 CCU98790.1 - 0.015 14.8 0.3 0.046 13.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) DUF2115 PF09888.4 CCU98790.1 - 0.031 14.3 1.5 0.33 11.0 0.0 2.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) Tol_Tol_Ttg2 PF05494.7 CCU98790.1 - 0.045 13.3 1.9 0.2 11.2 0.1 2.1 1 1 1 2 2 2 0 Toluene tolerance, Ttg2 Strep_SA_rep PF06696.6 CCU98790.1 - 0.064 13.0 0.6 0.064 13.0 0.4 2.3 3 0 0 3 3 3 0 Streptococcal surface antigen repeat DUF1090 PF06476.7 CCU98790.1 - 1.6 8.3 10.0 0.027 14.1 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF2489 PF10675.4 CCU98790.1 - 3.9 7.1 6.7 1.1 8.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) PGI PF00342.14 CCU98791.1 - 1.3e-211 703.2 0.0 1.5e-211 703.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase KH_1 PF00013.24 CCU98792.1 - 2.5e-05 23.8 0.0 3.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 KH domain DUF605 PF04652.11 CCU98792.1 - 1.9 7.8 11.6 2.1 7.6 8.1 1.1 1 0 0 1 1 1 0 Vta1 like Totivirus_coat PF05518.6 CCU98792.1 - 4.7 4.9 6.0 5 4.8 4.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein DUF1744 PF08490.7 CCU98793.1 - 2e-106 355.9 0.0 5.1e-106 354.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CCU98793.1 - 1.6e-63 214.5 0.2 2.5e-63 213.9 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CCU98793.1 - 6.3e-18 64.8 0.0 2.6e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CCU98793.1 - 2e-09 37.3 0.1 5.3e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CCU98793.1 - 0.00027 20.8 0.4 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily zf-DNA_Pol PF08996.5 CCU98793.1 - 2 7.7 7.4 5.1 6.4 5.1 1.6 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger UcrQ PF02939.11 CCU98795.1 - 2.2e-24 85.0 1.4 2.6e-24 84.8 0.9 1.0 1 0 0 1 1 1 1 UcrQ family Histone PF00125.19 CCU98797.1 - 1.3e-30 105.3 0.4 2e-30 104.7 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCU98797.1 - 9e-06 25.7 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCU98797.1 - 0.0074 16.3 0.1 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CCU98797.1 - 0.011 15.0 0.9 0.021 14.0 0.6 1.6 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CCU98797.1 - 0.017 14.8 0.1 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated WD40 PF00400.27 CCU98798.1 - 5.9e-35 117.9 11.4 3.4e-07 29.9 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 CCU98798.1 - 1.2e-06 28.4 0.5 0.0013 18.4 0.1 2.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCU98798.1 - 0.0067 14.6 3.3 0.19 9.8 0.1 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 GMP_synt_C PF00958.17 CCU98799.1 - 8e-40 134.4 0.1 1.9e-39 133.2 0.1 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 CCU98799.1 - 9.9e-39 132.7 0.0 2.1e-38 131.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 CCU98799.1 - 6e-12 44.9 0.1 1.1e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 CCU98799.1 - 9.9e-10 38.2 0.0 1.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 ThiI PF02568.9 CCU98799.1 - 0.00014 21.4 0.0 0.00041 19.8 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 CCU98799.1 - 0.00014 20.5 0.3 0.0003 19.4 0.1 1.5 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 CCU98799.1 - 0.00016 21.2 0.2 0.00033 20.2 0.0 1.5 2 0 0 2 2 2 1 Asparagine synthase Arginosuc_synth PF00764.14 CCU98799.1 - 0.0022 17.1 0.1 0.004 16.2 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 CCU98799.1 - 0.0036 16.5 0.1 0.03 13.5 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC WD40 PF00400.27 CCU98800.1 - 4.2e-16 58.1 4.9 6.2e-08 32.2 0.3 4.6 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF3553 PF12073.3 CCU98800.1 - 0.094 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) Cys_Met_Meta_PP PF01053.15 CCU98801.1 - 2.4e-27 95.2 0.0 4.3e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SNARE PF05739.14 CCU98801.1 - 7.7e-18 63.9 1.2 7.7e-18 63.9 0.8 2.8 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 CCU98801.1 - 6.5e-13 48.7 1.3 6.5e-13 48.7 0.9 2.7 3 0 0 3 3 3 1 Syntaxin Aminotran_1_2 PF00155.16 CCU98801.1 - 1.9e-05 23.7 0.0 6e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II IMD PF08397.6 CCU98801.1 - 0.026 13.8 0.6 0.054 12.7 0.4 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain FlaC_arch PF05377.6 CCU98801.1 - 0.11 12.3 0.0 0.45 10.4 0.0 2.1 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Tup_N PF08581.5 CCU98801.1 - 0.32 11.2 2.9 0.37 11.0 1.0 1.9 2 0 0 2 2 2 0 Tup N-terminal Rnk_N PF14760.1 CCU98801.1 - 6.7 6.8 6.9 21 5.2 0.1 3.6 3 0 0 3 3 3 0 Rnk N-terminus ATG16 PF08614.6 CCU98801.1 - 7.4 6.3 13.3 7.6 6.3 6.9 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Sdh_cyt PF01127.17 CCU98802.1 - 5.2e-23 81.1 1.7 6.9e-23 80.7 1.2 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Citrate_synt PF00285.16 CCU98803.1 - 8.7e-18 64.1 0.0 1.3e-15 56.9 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 CCU98803.1 - 8.6e-16 57.9 0.1 1.9e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 CCU98803.1 - 5.3e-10 39.6 0.0 1.1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 CCU98803.1 - 7.3e-07 28.7 0.0 1.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 CCU98803.1 - 2.1e-06 27.3 0.0 5.5e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.1 CCU98803.1 - 0.043 13.0 0.0 0.086 12.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Spc97_Spc98 PF04130.8 CCU98804.1 - 7.1e-101 338.1 0.5 9e-101 337.8 0.4 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family TP_methylase PF00590.15 CCU98805.1 - 8.9e-39 133.3 1.2 1.7e-38 132.4 0.9 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 CCU98805.1 - 1.1e-09 38.4 0.0 2.4e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CCU98805.1 - 2.8e-06 26.5 0.1 4.7e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CCU98805.1 - 1.4e-05 23.9 0.1 2.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central SAM_decarbox PF01536.11 CCU98806.1 - 4.3e-85 285.3 0.0 1.3e-84 283.7 0.0 1.7 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Peptidase_M16_C PF05193.16 CCU98807.1 - 2.5e-18 66.4 0.0 1.2e-13 51.1 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCU98807.1 - 6e-07 29.3 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Erythro-docking PF09277.6 CCU98807.1 - 0.039 13.6 0.8 0.15 11.7 0.6 2.0 1 0 0 1 1 1 0 Erythronolide synthase, docking Xan_ur_permease PF00860.15 CCU98808.1 - 2e-21 75.9 21.0 1.4e-13 50.1 5.5 2.1 2 0 0 2 2 2 2 Permease family Sulfate_transp PF00916.15 CCU98808.1 - 0.00012 21.1 7.4 0.0004 19.4 4.1 2.3 1 1 1 2 2 2 1 Sulfate transporter family Polysacc_deac_1 PF01522.16 CCU98809.1 - 1.8e-30 105.1 0.0 3.7e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Cu_amine_oxidN1 PF07833.6 CCU98809.1 - 0.027 14.7 0.1 0.06 13.6 0.1 1.6 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain Catalase PF00199.14 CCU98810.1 - 2.3e-164 546.6 0.3 2.9e-164 546.3 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CCU98810.1 - 4.5e-22 77.6 0.0 8.7e-22 76.7 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 CCU98810.1 - 0.003 17.0 0.5 0.007 15.8 0.2 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family Polysacc_deac_1 PF01522.16 CCU98811.1 - 8.2e-18 64.2 0.0 9.1e-11 41.4 0.0 2.6 1 1 1 2 2 2 2 Polysaccharide deacetylase RP-C_C PF11800.3 CCU98811.1 - 0.081 12.6 0.9 3.5 7.2 0.7 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region Macoilin PF09726.4 CCU98811.1 - 2.4 6.3 5.5 2.8 6.0 3.8 1.1 1 0 0 1 1 1 0 Transmembrane protein RhoGAP PF00620.22 CCU98813.1 - 5e-34 117.1 0.0 1.6e-33 115.4 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 CCU98813.1 - 6.4e-29 99.8 38.1 6.4e-13 48.5 2.8 4.8 5 0 0 5 5 5 4 LIM domain Aa_trans PF01490.13 CCU98814.1 - 2.6e-35 121.6 8.0 3.1e-35 121.4 5.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CCU98814.1 - 1.1e-05 24.4 7.5 1.5e-05 24.0 5.2 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.13 CCU98815.1 - 9.5e-27 93.4 1.8 2.6e-26 92.0 0.2 1.9 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Rad21_Rec8_N PF04825.8 CCU98816.1 - 5e-22 77.9 0.0 9.7e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CCU98816.1 - 4.7e-12 44.8 0.0 8.4e-12 44.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CCU98816.1 - 9.4e-05 22.1 0.0 0.00036 20.1 0.0 2.0 3 0 0 3 3 3 1 ScpA/B protein Sterol-sensing PF12349.3 CCU98817.1 - 4e-32 110.7 11.4 4e-32 110.7 7.9 2.1 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CCU98817.1 - 9.4e-10 37.0 9.4 1.4e-09 36.5 6.5 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 CCU98817.1 - 0.00087 19.0 0.1 0.045 13.6 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat TPR_11 PF13414.1 CCU98818.1 - 5.5e-27 93.2 7.4 4e-20 71.2 2.0 2.6 3 0 0 3 3 2 2 TPR repeat TPR_1 PF00515.23 CCU98818.1 - 1.2e-26 91.1 3.6 2.8e-08 32.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCU98818.1 - 1.8e-22 77.3 3.6 2.3e-07 30.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCU98818.1 - 2.5e-14 52.2 0.3 4e-06 26.6 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCU98818.1 - 3e-13 48.5 4.1 0.00065 19.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCU98818.1 - 1.3e-12 48.0 3.8 2.5e-07 31.1 0.1 2.9 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCU98818.1 - 2.7e-12 46.1 1.5 0.00021 21.6 0.0 4.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCU98818.1 - 3.3e-11 42.9 8.8 1.4e-07 31.3 0.4 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCU98818.1 - 1.8e-10 39.7 0.3 2.9e-05 23.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCU98818.1 - 1.9e-10 40.9 1.0 8e-06 26.0 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCU98818.1 - 1e-07 31.6 0.1 5.8e-05 22.8 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 CCU98818.1 - 1.6e-06 28.4 0.1 0.0002 21.6 0.1 2.3 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_10 PF13374.1 CCU98818.1 - 8.7e-05 22.3 2.3 1 9.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 CCU98818.1 - 9.9e-05 21.5 0.7 0.00022 20.3 0.0 1.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 CCU98818.1 - 0.00022 21.3 0.1 0.06 13.7 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCU98818.1 - 0.0017 18.6 6.2 3.4 8.3 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CCU98818.1 - 0.0039 17.2 0.6 0.011 15.8 0.5 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 CCU98818.1 - 0.23 11.3 1.3 3.3 7.5 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 CCU98818.1 - 3.3 7.6 13.9 1.5 8.7 1.4 3.4 2 2 1 3 3 3 0 MIT (microtubule interacting and transport) domain 6PGD PF00393.14 CCU98819.1 - 1.8e-132 440.9 0.0 2.2e-132 440.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CCU98819.1 - 9.7e-36 123.0 0.0 1.6e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CCU98819.1 - 0.023 14.7 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DEAD PF00270.24 CCU98820.1 - 1.1e-21 77.0 0.0 2.1e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU98820.1 - 1.5e-19 69.5 0.0 5.3e-18 64.6 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 CCU98820.1 - 1.1e-16 60.4 0.0 2.1e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 RQC domain AAA_30 PF13604.1 CCU98820.1 - 0.022 14.3 0.0 0.26 10.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 CCU98820.1 - 0.087 12.6 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ras PF00071.17 CCU98821.1 - 4.6e-50 169.1 0.0 5.4e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU98821.1 - 4.7e-12 46.4 0.0 6.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCU98821.1 - 9e-09 34.8 0.0 1.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCU98821.1 - 0.018 14.1 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 CCU98821.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 CCU98821.1 - 0.14 11.6 0.2 1.3 8.4 0.1 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MFS_2 PF13347.1 CCU98822.1 - 3.4e-08 32.3 11.2 3.4e-08 32.3 7.7 1.9 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 CCU98822.1 - 0.13 12.0 5.8 0.62 9.8 0.0 3.6 3 0 0 3 3 3 0 MFS_1 like family GTP_EFTU PF00009.22 CCU98823.1 - 1.5e-37 128.8 0.0 2.2e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCU98823.1 - 8.4e-26 89.9 0.0 2.7e-25 88.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CCU98823.1 - 5.1e-18 64.7 0.0 1.4e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 CCU98823.1 - 6.7e-07 29.8 0.0 1.2e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein EFG_II PF14492.1 CCU98823.1 - 1.1e-05 25.1 0.1 4.1e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 CCU98823.1 - 1.6e-05 24.8 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CCU98823.1 - 5.9e-05 23.1 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GBP PF02263.14 CCU98823.1 - 0.11 11.5 0.0 0.23 10.4 0.0 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Ras PF00071.17 CCU98823.1 - 0.11 11.8 0.0 0.31 10.4 0.0 1.7 1 1 0 1 1 1 0 Ras family SRPRB PF09439.5 CCU98823.1 - 0.15 11.2 0.0 0.37 9.9 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 CCU98823.1 - 0.29 10.9 0.0 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AAA PF00004.24 CCU98824.1 - 1.2e-12 48.1 0.0 2.1e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCU98824.1 - 6.4e-05 23.7 0.1 0.00024 21.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CCU98824.1 - 0.00014 20.9 0.0 0.00029 19.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCU98824.1 - 0.00021 20.9 1.7 0.00039 20.1 0.2 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 CCU98824.1 - 0.00031 20.1 1.1 0.098 12.0 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 CCU98824.1 - 0.00041 20.2 0.0 0.00063 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CCU98824.1 - 0.00041 20.2 0.0 0.00066 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCU98824.1 - 0.00054 20.1 0.0 0.0017 18.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCU98824.1 - 0.00065 19.4 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 CCU98824.1 - 0.00072 18.3 0.0 0.035 12.7 0.0 2.6 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CCU98824.1 - 0.00086 19.3 2.1 0.037 13.9 0.1 3.4 2 1 2 4 4 4 1 AAA ATPase domain AAA_33 PF13671.1 CCU98824.1 - 0.0025 17.6 0.0 0.0072 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCU98824.1 - 0.008 16.1 0.2 0.049 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCU98824.1 - 0.041 13.5 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 CCU98824.1 - 0.042 12.9 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Imm15 PF15590.1 CCU98824.1 - 0.054 12.5 0.3 7.6 5.6 0.0 2.9 3 0 0 3 3 3 0 Immunity protein 15 IstB_IS21 PF01695.12 CCU98824.1 - 0.067 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 CCU98824.1 - 0.097 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CCU98824.1 - 0.16 11.6 0.1 0.6 9.8 0.0 1.8 1 1 1 2 2 2 0 NTPase KaiC PF06745.8 CCU98824.1 - 0.18 10.9 0.0 0.48 9.5 0.0 1.6 2 0 0 2 2 2 0 KaiC Viral_helicase1 PF01443.13 CCU98824.1 - 0.19 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Exo_endo_phos PF03372.18 CCU98825.1 - 2.5e-22 80.0 0.6 3.2e-22 79.6 0.4 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CCU98825.1 - 2.4e-05 23.9 0.1 3.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Brr6_like_C_C PF10104.4 CCU98825.1 - 0.2 11.1 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Pyridoxal_deC PF00282.14 CCU98826.1 - 3.1e-60 203.6 0.0 4.2e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CCU98826.1 - 3.2e-05 22.8 0.0 4.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Lactamase_B_2 PF12706.2 CCU98826.1 - 0.0035 16.9 0.1 0.0073 15.8 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3826 PF12875.2 CCU98826.1 - 0.0073 16.0 0.6 0.013 15.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3826) Ribosomal_L10 PF00466.15 CCU98827.1 - 3.2e-26 91.1 0.3 8.3e-26 89.8 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CCU98827.1 - 2.3e-22 79.1 10.8 2.9e-22 78.8 6.3 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein ECH PF00378.15 CCU98829.1 - 1.8e-41 141.9 1.1 4e-20 71.9 0.2 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family SLT_L PF14718.1 CCU98829.1 - 5.4 6.8 10.3 13 5.6 0.1 3.6 4 0 0 4 4 4 0 Soluble lytic murein transglycosylase L domain WD40 PF00400.27 CCU98830.1 - 9.5e-20 69.6 0.1 1.1e-05 25.0 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF3312 PF11768.3 CCU98830.1 - 0.074 11.2 0.0 5.1 5.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) SAS4 PF15460.1 CCU98831.1 - 8.9e-06 25.5 1.6 1.6e-05 24.7 1.1 1.4 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.1 CCU98831.1 - 0.00069 20.0 1.0 0.00069 20.0 0.7 2.0 2 0 0 2 2 2 1 PEHE domain CHORD PF04968.7 CCU98832.1 - 8.3e-40 134.8 6.9 9.4e-22 77.0 1.3 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 CCU98832.1 - 6.4e-07 29.8 0.0 9.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 CS domain BTK PF00779.14 CCU98832.1 - 0.015 14.8 7.7 0.097 12.2 2.1 3.2 3 1 0 3 3 3 0 BTK motif ADH_zinc_N PF00107.21 CCU98835.1 - 5.5e-14 51.8 0.0 9.4e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCU98835.1 - 0.0064 16.2 0.1 0.022 14.5 0.1 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AA_permease PF00324.16 CCU98836.1 - 6.5e-121 403.9 33.5 8e-121 403.6 23.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCU98836.1 - 8.5e-31 106.9 35.4 1.1e-30 106.5 24.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3093 PF11292.3 CCU98836.1 - 2.5 7.9 8.1 0.22 11.3 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3093) Syja_N PF02383.13 CCU98837.1 - 9.7e-72 241.4 0.0 1.7e-71 240.6 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CCU98837.1 - 6.3e-26 91.8 0.0 1.6e-25 90.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pyr_redox_2 PF07992.9 CCU98837.1 - 1.6e-16 60.8 0.0 2.8e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCU98837.1 - 1.1e-12 48.2 0.1 2.3e-09 37.5 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 CCU98837.1 - 3e-06 26.1 1.0 0.0053 15.9 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CCU98837.1 - 9.6e-06 25.0 1.0 0.018 14.8 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CCU98837.1 - 9.7e-05 22.4 0.5 0.00073 19.6 0.3 2.5 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CCU98837.1 - 0.0051 16.1 0.8 0.02 14.2 0.2 2.2 2 0 0 2 2 2 1 EF hand DUF2360 PF10152.4 CCU98837.1 - 2.6 8.3 4.0 8.1 6.7 2.7 1.8 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Baculo_PEP_C PF04513.7 CCU98838.1 - 0.0066 16.2 0.8 0.0066 16.2 0.6 4.6 4 1 1 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 CCU98838.1 - 2 6.7 34.8 0.54 8.6 9.9 3.0 2 1 1 3 3 3 0 AAA domain GAS PF13851.1 CCU98838.1 - 7 5.7 51.1 0.1 11.7 6.0 4.8 4 1 1 6 6 6 0 Growth-arrest specific micro-tubule binding Peptidase_M16 PF00675.15 CCU98839.1 - 3.5e-39 133.9 0.0 5.9e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCU98839.1 - 6.6e-39 133.4 0.0 1.2e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Abhydrolase_6 PF12697.2 CCU98840.1 - 2.8e-20 73.1 0.3 4.3e-20 72.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCU98840.1 - 1.9e-13 50.3 0.0 4.6e-13 49.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCU98840.1 - 0.0001 22.0 0.8 0.00021 21.0 0.5 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 CCU98840.1 - 0.00098 18.6 0.1 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 CCU98840.1 - 0.0014 17.9 0.1 0.013 14.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CCU98840.1 - 0.0027 17.2 0.1 0.51 9.8 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 CCU98840.1 - 0.014 14.6 0.0 3.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Linker_histone PF00538.14 CCU98841.1 - 0.00082 19.4 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Pkinase PF00069.20 CCU98842.1 - 2.4e-10 39.9 0.0 4.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CCU98842.1 - 2.2e-06 27.6 1.8 2.4e-06 27.4 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCU98842.1 - 0.0018 17.3 0.1 0.005 15.9 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCU98842.1 - 0.0022 17.0 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CCU98842.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 CCU98842.1 - 0.18 10.9 0.3 0.33 10.0 0.2 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase IPK PF03770.11 CCU98843.1 - 2.3e-52 177.4 0.0 4.1e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase BROMI PF14961.1 CCU98843.1 - 0.2 8.7 0.0 0.28 8.2 0.0 1.1 1 0 0 1 1 1 0 Broad-minded protein Ribosomal_L14e PF01929.12 CCU98844.1 - 3.4e-28 97.7 2.9 5e-28 97.2 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 Oxidored_q6 PF01058.17 CCU98844.1 - 0.045 13.3 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit KOW PF00467.24 CCU98844.1 - 0.06 13.0 0.7 0.06 13.0 0.5 1.7 2 0 0 2 2 2 0 KOW motif Ribosomal_S8 PF00410.14 CCU98845.1 - 2.4e-24 85.6 0.0 2.9e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.13 CCU98846.1 - 5.4e-57 190.8 0.0 6.9e-57 190.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 CCU98846.1 - 0.018 15.7 0.2 0.058 14.0 0.0 1.8 1 1 1 2 2 2 0 Blue/Ultraviolet sensing protein C terminal Glyco_hydro_8 PF01270.12 CCU98847.1 - 1.1e-31 109.8 0.0 1.4e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 DNA_pol_A_exo1 PF01612.15 CCU98848.1 - 2.3e-19 69.5 0.0 3.4e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DnaJ PF00226.26 CCU98849.1 - 9e-16 57.3 0.1 9e-16 57.3 0.1 2.3 2 1 0 2 2 2 1 DnaJ domain GIIM PF08388.6 CCU98849.1 - 0.05 13.4 1.0 6.2 6.6 0.0 3.3 3 0 0 3 3 3 0 Group II intron, maturase-specific domain SpoVR PF04293.8 CCU98849.1 - 0.14 10.4 5.0 0.22 9.8 3.5 1.2 1 0 0 1 1 1 0 SpoVR like protein IpaD PF06511.6 CCU98849.1 - 0.63 8.9 6.0 1 8.3 4.1 1.2 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD tRNA-synt_2b PF00587.20 CCU98850.1 - 1.8e-33 115.5 0.2 1.8e-33 115.5 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CCU98850.1 - 4.9e-23 81.1 5.7 9.2e-23 80.3 4.0 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.10 CCU98850.1 - 0.056 13.4 3.4 0.043 13.8 1.0 1.7 2 0 0 2 2 2 0 Fez1 COG2 PF06148.6 CCU98850.1 - 0.066 13.0 0.7 0.15 11.9 0.5 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ProRS-C_1 PF09180.6 CCU98851.1 - 1e-25 89.4 0.2 2.1e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 CCU98851.1 - 5.9e-23 81.3 0.0 9e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCU98851.1 - 5.5e-17 61.5 0.0 1.6e-15 56.8 0.0 3.3 5 0 0 5 5 5 1 Anticodon binding domain tRNA_edit PF04073.10 CCU98851.1 - 2.2e-13 50.1 0.3 3.8e-13 49.3 0.2 1.3 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain zinc_ribbon_2 PF13240.1 CCU98851.1 - 0.14 11.7 0.2 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain SRP19 PF01922.12 CCU98852.1 - 1.4e-05 25.6 0.0 3.4e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 SRP19 protein DUF3617 PF12276.3 CCU98852.1 - 0.024 14.1 3.9 0.024 14.1 2.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) SKN1 PF03935.10 CCU98853.1 - 4.4e-180 599.1 0.6 5.7e-180 598.7 0.4 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF485 PF04341.7 CCU98853.1 - 0.33 10.6 0.7 0.6 9.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DEAD PF00270.24 CCU98854.1 - 1.9e-20 73.0 0.0 6.1e-20 71.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU98854.1 - 0.0019 18.0 0.1 0.0038 17.0 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_25 PF13481.1 CCU98854.1 - 0.061 12.7 0.1 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Fer2 PF00111.22 CCU98855.1 - 1e-11 44.3 0.2 1.4e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Sugar_tr PF00083.19 CCU98856.1 - 8.1e-55 186.1 16.7 1.3e-54 185.5 11.6 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCU98856.1 - 1.5e-07 30.5 44.7 1.9e-07 30.1 28.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 CCU98857.1 - 8.7e-22 76.1 9.0 6.3e-06 25.8 0.0 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 CCU98857.1 - 0.00011 22.0 0.0 0.00028 20.6 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 CCU98857.1 - 0.00037 18.4 0.3 0.0072 14.1 0.1 2.3 2 1 0 2 2 2 1 IKI3 family TFIIIC_delta PF12657.2 CCU98857.1 - 0.039 13.6 0.1 5 6.8 0.0 2.7 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Pkinase PF00069.20 CCU98858.1 - 4.7e-73 245.5 0.0 5.4e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98858.1 - 2.2e-35 122.0 0.0 2.8e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU98858.1 - 0.0027 16.6 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCU98858.1 - 0.03 14.0 0.0 0.13 11.9 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCU98858.1 - 0.064 12.0 0.0 0.14 10.9 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Utp12 PF04003.7 CCU98859.1 - 3.2e-11 43.0 1.1 4.5e-11 42.6 0.1 1.8 2 0 0 2 2 2 1 Dip2/Utp12 Family TraD PF06412.6 CCU98861.1 - 0.25 10.9 1.1 0.52 9.9 0.1 2.0 2 0 0 2 2 2 0 Conjugal transfer protein TraD PRELI PF04707.9 CCU98862.1 - 8e-19 67.7 0.0 1.1e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family Suf PF05843.9 CCU98863.1 - 2.3e-72 244.0 1.8 3.1e-68 230.5 0.0 3.4 3 0 0 3 3 3 3 Suppressor of forked protein (Suf) NRDE-2 PF08424.5 CCU98863.1 - 3.9 6.2 12.5 0.42 9.4 0.0 3.9 3 1 1 4 4 4 0 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 CCU98864.1 - 2.7e-48 161.4 27.1 6.5e-16 57.7 0.0 6.3 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 CCU98864.1 - 1.4e-43 144.7 20.0 2.3e-06 26.9 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 CCU98864.1 - 4.1e-36 119.9 21.5 0.0001 21.9 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 CCU98864.1 - 5.4e-23 80.7 21.4 2.1e-11 43.5 0.0 6.5 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 CCU98864.1 - 1.4e-20 73.3 25.8 0.0002 21.9 0.0 7.3 3 3 5 8 8 8 8 Tetratricopeptide repeat TPR_14 PF13428.1 CCU98864.1 - 4.7e-18 64.0 13.4 0.011 16.2 0.8 9.4 3 3 6 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 CCU98864.1 - 4.6e-17 60.4 13.5 0.033 13.9 0.0 9.0 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCU98864.1 - 1.4e-14 54.1 19.9 0.00067 19.9 0.2 7.2 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCU98864.1 - 3.9e-12 45.3 3.7 0.16 12.2 0.0 6.5 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCU98864.1 - 2.7e-10 39.2 12.0 0.24 11.2 0.0 7.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 CCU98864.1 - 2.2e-05 24.1 11.6 0.012 15.4 0.0 5.5 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCU98864.1 - 0.00018 21.7 15.8 14 6.3 0.0 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat Apc3 PF12895.2 CCU98864.1 - 0.00045 20.2 13.3 0.52 10.4 0.8 4.6 3 3 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CCU98864.1 - 0.0091 15.9 10.2 0.025 14.4 0.0 5.3 7 0 0 7 7 6 1 Tetratricopeptide repeat Inhibitor_I9 PF05922.11 CCU98864.1 - 0.023 15.2 0.1 0.12 12.9 0.1 2.4 2 0 0 2 2 1 0 Peptidase inhibitor I9 YecM PF06185.7 CCU98864.1 - 0.039 13.1 0.0 0.37 9.9 0.0 2.3 3 0 0 3 3 3 0 YecM protein Strep_SA_rep PF06696.6 CCU98864.1 - 0.19 11.5 5.8 0.55 10.0 0.1 3.7 3 0 0 3 3 3 0 Streptococcal surface antigen repeat TPR_4 PF07721.9 CCU98864.1 - 0.39 11.2 3.2 17 6.1 0.0 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat RNA_pol_3_Rpc31 PF11705.3 CCU98865.1 - 8.4e-34 117.5 13.4 1.5e-33 116.7 9.3 1.3 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Zn_clus PF00172.13 CCU98866.1 - 1.2e-06 28.2 5.4 2e-06 27.5 3.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3414 PF11894.3 CCU98867.1 - 2.2e-218 727.7 0.0 2.8e-218 727.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) RE_Eco29kI PF09517.5 CCU98867.1 - 0.051 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Eco29kI restriction endonuclease Pyridoxal_deC PF00282.14 CCU98868.1 - 3.3e-109 364.7 0.0 3.9e-109 364.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 CCU98868.1 - 0.16 10.1 0.0 0.32 9.2 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CAP_N PF01213.14 CCU98869.1 - 10 5.3 5.8 1.3 8.2 1.1 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal EI24 PF07264.6 CCU98870.1 - 0.00045 19.7 3.4 0.0013 18.2 2.4 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4112 PF13430.1 CCU98870.1 - 0.14 12.0 0.1 1 9.3 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4112) TruB_N PF01509.13 CCU98873.1 - 4.8e-38 130.6 0.0 3.6e-37 127.7 0.0 1.9 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Formyl_trans_N PF00551.14 CCU98874.1 - 7.3e-22 77.7 0.0 1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase DUF500 PF04366.7 CCU98875.1 - 1.1e-37 128.2 0.0 9.3e-37 125.2 0.0 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF500) Esterase PF00756.15 CCU98876.1 - 1.2e-45 155.9 0.0 1.3e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CCU98876.1 - 8.7e-08 32.0 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCU98876.1 - 1.7e-06 27.3 0.0 2.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CCU98876.1 - 1.1e-05 25.4 0.2 1.7e-05 24.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 CCU98876.1 - 0.0011 18.2 0.0 0.038 13.2 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 CCU98876.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DnaJ PF00226.26 CCU98877.1 - 1.6e-10 40.5 0.2 2.7e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Abi PF02517.11 CCU98879.1 - 0.0047 17.0 3.1 0.0047 17.0 2.1 2.2 2 1 0 2 2 2 1 CAAX protease self-immunity Sdh_cyt PF01127.17 CCU98879.1 - 0.45 10.3 4.6 0.22 11.3 0.5 2.0 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Inositol_P PF00459.20 CCU98880.1 - 4.8e-52 176.9 0.3 1.8e-51 175.0 0.2 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family AAA_5 PF07728.9 CCU98882.1 - 2.1e-69 231.6 0.0 7.8e-29 100.1 0.0 3.4 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 CCU98882.1 - 0.00046 20.3 0.0 0.00088 19.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_3 PF07726.6 CCU98882.1 - 0.0028 17.2 0.0 0.22 11.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCU98882.1 - 0.03 14.2 0.0 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCU98882.1 - 0.063 13.4 0.0 2.2 8.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 CCU98882.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CdhC PF03598.10 CCU98882.1 - 0.35 9.2 0.0 0.56 8.6 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Raptor_N PF14538.1 CCU98883.1 - 1.3e-62 210.1 0.0 2.3e-62 209.3 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 CCU98883.1 - 5.1e-07 29.3 0.4 0.69 9.8 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT PF02985.17 CCU98883.1 - 0.0032 17.4 22.7 0.0039 17.1 0.0 6.8 8 0 0 8 8 8 2 HEAT repeat BBS2_Mid PF14783.1 CCU98883.1 - 0.0095 15.7 0.0 6.3 6.6 0.0 3.0 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.1 CCU98883.1 - 0.026 14.8 4.0 0.044 14.0 0.3 3.3 3 1 1 4 4 4 0 HEAT repeats Cnd1 PF12717.2 CCU98883.1 - 0.6 9.9 1.6 8.7 6.1 0.0 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CCU98883.1 - 9.9 6.8 17.2 0.16 12.4 1.4 5.2 4 1 1 5 5 5 0 HEAT-like repeat IBN_N PF03810.14 CCU98884.1 - 3.2e-07 30.1 0.0 1.2e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF1546 PF07571.8 CCU98884.1 - 0.0064 16.5 0.0 0.13 12.4 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1546) Cse1 PF08506.5 CCU98884.1 - 0.012 14.1 0.0 0.02 13.4 0.0 1.2 1 0 0 1 1 1 0 Cse1 RIX1 PF08167.7 CCU98884.1 - 0.065 12.8 0.0 2.5 7.7 0.0 3.0 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis Ank_2 PF12796.2 CCU98885.1 - 3.8e-07 30.3 0.3 6.2e-07 29.6 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCU98885.1 - 2e-05 24.9 0.1 0.0004 20.8 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCU98885.1 - 4e-05 23.2 1.3 0.055 13.3 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeat zf-CCCH_2 PF14608.1 CCU98885.1 - 4.5e-05 23.2 7.1 4.5e-05 23.2 4.9 2.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type Ank_3 PF13606.1 CCU98885.1 - 0.00012 21.9 0.2 0.024 14.8 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH PF00642.19 CCU98885.1 - 0.00022 20.8 14.0 0.0038 16.8 1.2 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_5 PF13857.1 CCU98885.1 - 0.00023 21.3 0.4 0.1 12.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Pkinase PF00069.20 CCU98886.1 - 1.6e-58 197.9 0.0 2.1e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98886.1 - 2.3e-23 82.6 0.1 3.9e-23 81.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase BolA PF01722.13 CCU98886.1 - 1.8e-08 34.1 0.2 8.4e-08 32.0 0.1 2.0 1 1 0 1 1 1 1 BolA-like protein RIO1 PF01163.17 CCU98886.1 - 3e-05 23.4 0.2 0.00032 20.1 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 CCU98886.1 - 0.00077 18.5 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCU98886.1 - 0.035 13.0 0.0 0.066 12.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CCU98886.1 - 0.041 13.6 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family 3Beta_HSD PF01073.14 CCU98887.1 - 7.7e-58 195.3 0.0 1e-53 181.8 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCU98887.1 - 9.7e-30 103.7 0.0 1.4e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCU98887.1 - 1.7e-15 56.6 0.0 2.8e-13 49.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CCU98887.1 - 5.1e-11 42.9 0.0 1.5e-10 41.3 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CCU98887.1 - 5.4e-11 41.9 0.0 8.8e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CCU98887.1 - 0.0018 17.2 0.0 0.0065 15.3 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CCU98887.1 - 0.0026 17.6 0.0 0.0062 16.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase DNA_pol_B_exo1 PF03104.14 CCU98887.1 - 0.027 13.3 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain TrkA_N PF02254.13 CCU98887.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.8 CCU98887.1 - 0.11 11.6 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family ACBP PF00887.14 CCU98889.1 - 2.9e-27 94.1 0.7 3.8e-26 90.5 0.4 2.1 1 1 0 1 1 1 1 Acyl CoA binding protein Methyltransf_23 PF13489.1 CCU98892.1 - 1.9e-14 53.7 0.0 1.4e-13 50.8 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCU98892.1 - 4.8e-13 49.4 0.0 3.3e-12 46.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCU98892.1 - 1.2e-08 35.2 0.0 8e-08 32.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCU98892.1 - 1.4e-08 34.9 0.0 4.1e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCU98892.1 - 1.8e-07 30.8 0.0 1.1e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCU98892.1 - 2.6e-07 31.1 0.0 6.4e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CCU98892.1 - 1.1e-06 27.8 0.0 0.0021 17.1 0.0 2.2 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 CCU98892.1 - 8.9e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCU98892.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.1 CCU98892.1 - 0.031 15.1 0.0 0.13 13.1 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain CheR PF01739.13 CCU98892.1 - 0.045 13.0 0.0 7.9 5.7 0.0 2.3 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_8 PF05148.10 CCU98892.1 - 0.045 13.3 0.0 0.73 9.4 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase Ham1p_like PF01725.11 CCU98893.1 - 0.0013 18.1 0.0 0.0013 18.1 0.0 1.1 1 0 0 1 1 1 1 Ham1 family Ham1p_like PF01725.11 CCU98894.1 - 2.5e-23 82.4 0.0 5e-23 81.4 0.0 1.4 1 1 0 1 1 1 1 Ham1 family GTP_EFTU PF00009.22 CCU98898.1 - 5.2e-62 208.6 0.1 7.4e-62 208.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCU98898.1 - 7.1e-38 128.8 0.0 1.7e-37 127.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CCU98898.1 - 3.3e-21 74.9 0.0 7e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CCU98898.1 - 1.1e-12 47.6 0.0 2.7e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CCU98898.1 - 3.9e-12 46.1 0.0 2.6e-11 43.4 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCU98898.1 - 5.1e-05 23.1 0.0 9.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase NARP1 PF12569.3 CCU98899.1 - 1.8e-156 521.9 17.5 8.8e-139 463.5 9.5 2.7 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 CCU98899.1 - 3.9e-12 45.0 27.4 2.6e-05 23.8 0.1 8.4 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCU98899.1 - 1.1e-11 44.2 21.9 0.0042 16.7 0.1 7.5 6 1 0 7 7 7 5 TPR repeat TPR_14 PF13428.1 CCU98899.1 - 1.9e-10 40.4 31.7 0.069 13.8 0.2 11.6 8 3 3 11 11 11 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCU98899.1 - 1.8e-08 33.6 7.3 0.0014 18.1 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCU98899.1 - 1.7e-07 31.7 47.6 0.0085 16.7 0.9 9.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCU98899.1 - 7.8e-06 25.7 27.1 0.0044 16.9 0.1 6.9 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCU98899.1 - 0.00038 20.0 15.1 0.11 12.3 0.1 7.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCU98899.1 - 0.00062 19.5 0.4 0.00062 19.5 0.3 6.6 8 1 0 8 8 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCU98899.1 - 0.00068 19.9 0.3 0.00068 19.9 0.2 8.1 7 2 1 9 9 9 2 Tetratricopeptide repeat Transcrip_act PF04949.8 CCU98899.1 - 0.045 13.3 0.1 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 Transcriptional activator Fis1_TPR_C PF14853.1 CCU98899.1 - 0.1 12.4 7.8 12 5.8 0.0 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 CCU98899.1 - 0.2 12.1 0.0 0.2 12.1 0.0 7.6 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCU98899.1 - 0.36 10.7 0.0 0.36 10.7 0.0 4.8 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCU98899.1 - 0.74 9.8 0.0 0.74 9.8 0.0 7.4 9 0 0 9 9 9 0 Tetratricopeptide repeat C2 PF00168.25 CCU98900.1 - 1.3e-06 28.1 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.19 CCU98900.1 - 5e-05 23.7 1.6 5.9e-05 23.4 0.1 2.0 2 1 0 2 2 2 1 Protein kinase C terminal domain PP-binding PF00550.20 CCU98901.1 - 9.9e-15 54.5 0.4 1.3e-14 54.2 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CCU98901.1 - 6.5e-06 26.0 0.5 1.1e-05 25.3 0.4 1.4 1 1 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 CCU98901.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.3 1 1 0 1 1 1 0 Ribosomal subunit 39S Ribosomal_L17 PF01196.14 CCU98902.1 - 4.8e-29 100.7 0.3 1.6e-28 99.1 0.0 2.0 2 1 0 2 2 2 1 Ribosomal protein L17 Halogen_Hydrol PF10112.4 CCU98902.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF1751 PF08551.5 CCU98903.1 - 1.5e-05 25.2 0.3 2.3e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) SLAC1 PF03595.12 CCU98904.1 - 5.8e-82 274.9 39.7 6.6e-82 274.8 27.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4231 PF14015.1 CCU98904.1 - 4.3 7.3 12.3 8.6 6.3 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) WD40 PF00400.27 CCU98905.1 - 6.8e-64 209.6 10.3 2.5e-09 36.6 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 CCU98905.1 - 3.5e-06 26.8 0.0 0.00052 19.7 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCU98905.1 - 0.011 13.9 0.0 0.011 13.9 0.0 3.4 4 1 1 5 5 5 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCU98905.1 - 0.02 13.6 0.0 1.5 7.4 0.0 2.9 2 2 1 3 3 3 0 Nup133 N terminal like TFIIIC_delta PF12657.2 CCU98905.1 - 0.086 12.5 1.1 0.52 9.9 0.0 2.8 2 2 0 2 2 2 0 Transcription factor IIIC subunit delta N-term BAT2_N PF07001.6 CCU98905.1 - 0.55 10.5 12.5 0.08 13.2 5.1 1.9 1 1 1 2 2 2 0 BAT2 N-terminus Ribosomal_S7 PF00177.16 CCU98906.1 - 4.5e-39 133.3 0.5 5.4e-39 133.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CtaG_Cox11 PF04442.9 CCU98907.1 - 5.9e-54 181.9 0.1 7.4e-54 181.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DKCLD PF08068.7 CCU98908.1 - 5e-29 100.0 0.0 2.5e-28 97.7 0.0 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 CCU98908.1 - 5.3e-23 81.8 6.3 9.8e-22 77.7 0.2 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CCU98908.1 - 6.3e-21 73.8 0.6 1.3e-20 72.9 0.4 1.6 1 0 0 1 1 1 1 PUA domain CENP-T PF15511.1 CCU98908.1 - 1.3 8.2 20.9 1.8 7.7 14.5 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RNase_H2-Ydr279 PF09468.5 CCU98908.1 - 1.8 7.6 22.9 3.4 6.7 15.9 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Ribosomal_L22e PF01776.12 CCU98909.1 - 1.8e-44 150.2 0.0 2.3e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Spb1_C PF07780.7 CCU98910.1 - 3e-70 236.0 18.5 3e-70 236.0 12.8 3.8 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 CCU98910.1 - 1.4e-53 181.5 0.4 2.5e-53 180.7 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 CCU98910.1 - 3.3e-46 156.6 7.1 3.3e-46 156.6 5.0 5.4 5 1 0 6 6 6 1 Domain of unknown function (DUF3381) eIF2A PF08662.6 CCU98911.1 - 2e-41 141.8 0.7 1.4e-37 129.2 0.1 4.1 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 CCU98911.1 - 0.00024 20.6 0.0 0.00068 19.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CCU98911.1 - 0.00033 20.4 1.9 0.43 10.5 0.0 5.1 7 0 0 7 7 7 1 WD domain, G-beta repeat RRM_5 PF13893.1 CCU98911.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt5-NGN PF03439.8 CCU98911.1 - 0.05 13.3 0.1 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section RRM_6 PF14259.1 CCU98911.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PEX11 PF05648.9 CCU98912.1 - 1.3e-63 214.2 2.0 1.4e-63 214.1 1.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DGCR6 PF07324.6 CCU98912.1 - 0.0015 18.0 0.1 0.0022 17.5 0.0 1.1 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein Sel1 PF08238.7 CCU98913.1 - 1.2e-06 28.9 16.6 0.0019 18.7 0.2 5.6 4 1 0 4 4 4 4 Sel1 repeat Ribosomal_L32p PF01783.18 CCU98914.1 - 0.0012 18.9 2.8 0.0019 18.3 1.9 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family ICL PF00463.16 CCU98915.1 - 6.4e-258 856.2 2.7 7.2e-258 856.0 1.9 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CCU98915.1 - 3.1e-09 36.4 0.0 5.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 CCU98915.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain DUF367 PF04034.8 CCU98916.1 - 1e-42 144.7 0.0 1.3e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CCU98916.1 - 1.6e-12 46.7 0.2 2.9e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Prenyltrans PF00432.16 CCU98918.1 - 5.1e-55 182.6 10.6 2e-10 40.0 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCU98918.1 - 4.8e-35 120.3 0.2 1.1e-15 57.9 0.1 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCU98918.1 - 2.9e-12 46.5 0.1 2.7e-09 36.9 0.0 3.5 1 1 2 3 3 3 2 Prenyltransferase-like MutS_V PF00488.16 CCU98919.1 - 2.7e-71 239.7 0.1 4.6e-71 238.9 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCU98919.1 - 5.9e-31 107.8 4.3 1.1e-30 106.9 3.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CCU98919.1 - 4.3e-22 78.2 0.0 3e-21 75.5 0.0 2.3 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 CCU98919.1 - 9.7e-07 28.8 0.0 1.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 CCU98919.1 - 1.2e-06 28.6 0.0 2.9e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 CCU98919.1 - 0.11 12.0 2.1 0.29 10.6 0.4 2.5 1 1 1 2 2 2 0 P-loop containing region of AAA domain RNA_pol_Rpb6 PF01192.17 CCU98920.1 - 2.4e-10 39.9 0.3 3.9e-10 39.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 AMP-binding PF00501.23 CCU98921.1 - 3.5e-49 167.3 0.0 5.3e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 CCU98921.1 - 1.5e-10 41.2 1.8 4e-10 39.7 1.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 CCU98921.1 - 2.1e-10 39.6 4.2 0.014 14.8 0.0 7.2 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) GH3 PF03321.8 CCU98921.1 - 0.17 10.3 0.0 4.2 5.7 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter TPPK_C PF12555.3 CCU98922.1 - 0.25 11.1 3.3 0.67 9.7 2.3 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Carn_acyltransf PF00755.15 CCU98924.1 - 2.5e-153 511.3 0.0 2.8e-153 511.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase tRNA-synt_2 PF00152.15 CCU98926.1 - 1.6e-80 270.4 0.2 2.1e-80 269.9 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCU98926.1 - 0.00021 21.0 0.0 0.00045 20.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCU98926.1 - 0.035 13.2 0.2 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Tubulin PF00091.20 CCU98927.1 - 3.1e-67 226.5 0.0 4.5e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCU98927.1 - 1.3e-40 138.3 0.1 1.9e-40 137.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CCU98927.1 - 2.9e-05 24.1 0.0 5.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Cupin_8 PF13621.1 CCU98928.1 - 2.6e-16 59.8 0.1 9.3e-15 54.8 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CCU98928.1 - 4.5e-11 43.0 0.1 9.5e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 CCU98928.1 - 0.0039 16.4 0.0 0.0071 15.6 0.0 1.5 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.6 CCU98928.1 - 0.044 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Cupin domain RhoGEF PF00621.15 CCU98929.1 - 1.2e-37 129.5 0.0 1.7e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain TLD PF07534.11 CCU98929.1 - 6.5e-21 74.7 0.0 3.2e-19 69.2 0.0 2.8 2 1 0 2 2 2 1 TLD LRR_4 PF12799.2 CCU98929.1 - 8.8e-12 44.3 1.2 9.9e-06 25.0 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCU98929.1 - 1.6e-09 37.3 2.0 0.0013 18.4 0.1 2.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CCU98929.1 - 1.8e-06 27.2 2.4 3.6 7.9 0.1 5.4 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 CCU98929.1 - 5.1e-05 22.8 0.5 11 6.7 0.0 5.2 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 CCU98929.1 - 0.017 15.1 3.2 0.18 11.9 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat CPSF_A PF03178.10 CCU98930.1 - 8.8e-85 284.6 0.0 6.3e-84 281.7 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 CCU98930.1 - 4.7e-69 232.8 0.0 7.2e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ_3 PF13570.1 CCU98930.1 - 2.7 8.3 5.7 47 4.4 0.1 5.6 8 0 0 8 8 8 0 PQQ-like domain AdoMet_MTase PF07757.8 CCU98931.1 - 9.3e-30 103.0 0.1 1.5e-28 99.1 0.1 2.4 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 CCU98931.1 - 0.00025 20.7 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF2962 PF11176.3 CCU98933.1 - 3.4e-35 120.8 0.3 4e-35 120.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF3841 PF12952.2 CCU98933.1 - 0.067 12.6 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) ADH_zinc_N PF00107.21 CCU98934.1 - 4.3e-20 71.5 0.9 7.3e-20 70.8 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCU98934.1 - 6.7e-08 33.4 1.5 1.1e-07 32.8 0.2 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.5 CCU98934.1 - 0.031 14.2 0.2 0.092 12.7 0.1 1.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal PsbT PF01405.12 CCU98935.1 - 0.15 11.6 2.1 0.42 10.2 1.4 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Myb_DNA-binding PF00249.26 CCU98936.1 - 2.2e-09 37.2 0.8 4.7e-09 36.1 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Bud13 PF09736.4 CCU98937.1 - 3.7e-40 137.5 3.6 3.7e-40 137.5 2.5 2.0 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex zf-Nse PF11789.3 CCU98938.1 - 6e-14 51.3 0.0 9.8e-14 50.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 CCU98938.1 - 0.00011 22.0 0.0 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 CCU98938.1 - 0.00025 20.7 0.0 0.00051 19.7 0.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 CCU98938.1 - 0.011 14.9 0.2 0.033 13.3 0.0 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger DUF342 PF03961.8 CCU98938.1 - 0.17 10.2 0.1 0.26 9.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 CCU98938.1 - 0.25 11.3 4.8 0.22 11.5 0.9 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AcylCoA_dehyd_C PF12186.3 CCU98938.1 - 0.53 10.1 3.6 5.7 6.8 0.3 2.3 1 1 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal CTP_synth_N PF06418.9 CCU98940.1 - 2.6e-116 387.5 0.0 3.6e-116 387.0 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CCU98940.1 - 4.1e-49 166.6 0.0 6.2e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCU98940.1 - 0.00072 19.0 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 CCU98940.1 - 0.006 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Steroid_dh PF02544.11 CCU98941.1 - 2.2e-14 53.4 0.7 3.1e-12 46.4 0.5 2.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase SNF2_N PF00176.18 CCU98942.1 - 1.2e-70 237.6 1.3 2.5e-70 236.6 0.9 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 CCU98942.1 - 1.4e-53 180.7 16.7 1.4e-53 180.7 11.6 2.4 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 CCU98942.1 - 6.5e-13 48.3 0.0 1.5e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCU98942.1 - 8.3e-06 25.7 0.1 3.1e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CCU98942.1 - 6.6e-05 21.8 2.1 0.00043 19.1 0.0 2.6 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CCU98942.1 - 0.0035 16.8 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase YCII PF03795.9 CCU98942.1 - 0.053 13.7 1.4 0.26 11.5 0.0 3.0 3 0 0 3 3 3 0 YCII-related domain Pex14_N PF04695.8 CCU98943.1 - 2.6e-06 27.4 1.6 2.6e-06 27.4 1.1 3.0 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_S28e PF01200.13 CCU98944.1 - 1.5e-31 107.9 1.1 1.5e-31 107.9 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Adaptin_N PF01602.15 CCU98945.1 - 4.8e-110 368.3 0.0 6.7e-110 367.8 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CCU98945.1 - 7.3e-48 162.2 0.0 1.6e-47 161.1 0.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CCU98945.1 - 3.4e-15 56.0 3.6 0.00031 20.9 0.2 5.9 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.17 CCU98945.1 - 4.4e-05 23.2 6.9 0.5 10.5 0.1 6.4 6 0 0 6 6 6 1 HEAT repeat Arm PF00514.18 CCU98945.1 - 0.0016 18.2 2.6 13 5.7 0.0 5.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 CCU98945.1 - 0.0032 17.7 9.6 4.5 8.0 0.1 6.2 6 1 0 6 6 6 2 PBS lyase HEAT-like repeat Cnd1 PF12717.2 CCU98945.1 - 0.0032 17.3 0.1 1.3 8.8 0.0 2.9 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.2 CCU98945.1 - 0.037 13.0 0.2 0.83 8.5 0.0 2.3 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.1 CCU98945.1 - 0.9 10.1 11.7 1.3 9.5 1.8 4.7 4 1 1 5 5 5 0 HEAT-like repeat bZIP_2 PF07716.10 CCU98946.1 - 1.3e-10 40.9 14.9 1.3e-10 40.9 10.3 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CCU98946.1 - 0.00035 20.4 15.4 0.00066 19.5 10.4 1.7 1 1 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 CCU98946.1 - 0.0022 17.6 0.3 0.004 16.8 0.2 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Rab5-bind PF09311.6 CCU98946.1 - 0.0056 16.5 2.4 0.0056 16.5 1.7 2.0 2 0 0 2 2 2 1 Rabaptin-like protein DUF2205 PF10224.4 CCU98946.1 - 0.013 15.1 1.0 0.036 13.6 0.7 1.7 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) TSC22 PF01166.13 CCU98946.1 - 0.015 15.2 0.4 0.033 14.1 0.3 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_Maf PF03131.12 CCU98946.1 - 0.016 15.4 8.2 0.016 15.4 5.7 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF904 PF06005.7 CCU98946.1 - 0.044 14.0 1.7 0.044 14.0 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Phlebovirus_NSM PF07246.6 CCU98946.1 - 0.16 11.0 1.8 0.24 10.4 1.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DivIC PF04977.10 CCU98946.1 - 0.2 11.1 1.5 0.43 10.1 1.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Spore_III_AF PF09581.5 CCU98946.1 - 0.27 11.1 3.1 0.55 10.0 2.2 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Sugar_tr PF00083.19 CCU98947.1 - 2.5e-89 299.9 25.6 7.9e-67 225.7 8.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCU98947.1 - 2.3e-12 46.2 38.6 2.7e-09 36.2 12.5 3.9 2 1 0 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.11 CCU98948.1 - 8.3e-13 47.7 51.2 6.9e-12 44.7 34.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily BatD PF13584.1 CCU98948.1 - 0.0075 14.9 0.1 1 7.9 0.0 2.8 3 0 0 3 3 3 2 Oxygen tolerance ParA PF10609.4 CCU98949.1 - 2.8e-30 104.0 0.1 5.1e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCU98949.1 - 5.7e-16 58.4 0.1 1.5e-15 57.1 0.1 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CCU98949.1 - 4.3e-07 29.9 0.4 2.1e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCU98949.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 CCU98949.1 - 0.0026 16.9 0.0 0.0049 15.9 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 CCU98949.1 - 0.0067 15.5 1.4 0.0067 15.5 1.0 1.7 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.13 CCU98949.1 - 0.0091 15.2 0.2 0.058 12.5 0.1 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_19 PF13245.1 CCU98949.1 - 0.37 10.5 3.9 4.7 7.0 0.7 2.5 2 0 0 2 2 2 0 Part of AAA domain FAD_binding_2 PF00890.19 CCU98950.1 - 4.2e-126 421.1 4.4 5.6e-126 420.7 3.0 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CCU98950.1 - 1.3e-45 154.4 1.4 1.8e-45 153.8 1.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 CCU98950.1 - 5.9e-06 26.3 0.4 0.0038 17.1 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCU98950.1 - 2.1e-05 23.7 0.4 0.0076 15.3 0.1 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 CCU98950.1 - 8.2e-05 21.6 1.5 0.036 12.9 1.8 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 CCU98950.1 - 0.00015 20.7 0.4 0.0034 16.3 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCU98950.1 - 0.016 14.2 0.3 0.032 13.2 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 CCU98950.1 - 0.3 9.4 4.4 0.55 8.6 0.7 2.8 3 0 0 3 3 3 0 HI0933-like protein zf-C2HC5 PF06221.8 CCU98952.1 - 1.6e-11 43.7 2.2 2.8e-11 42.9 1.5 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type PHD PF00628.24 CCU98953.1 - 2.9e-07 30.0 8.7 6.4e-07 28.9 6.0 1.6 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.1 CCU98953.1 - 3.1e-07 30.1 0.0 6.9e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CCU98953.1 - 1e-06 28.9 0.3 2.8e-05 24.3 0.1 2.5 2 1 0 2 2 2 1 JmjC domain, hydroxylase PHD_2 PF13831.1 CCU98953.1 - 0.00037 19.7 6.3 0.00079 18.6 4.3 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 CCU98953.1 - 0.0017 18.0 3.5 0.0042 16.7 2.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 CCU98953.1 - 0.018 14.8 2.4 0.053 13.3 1.7 1.8 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H_2 PF13832.1 CCU98953.1 - 0.032 14.2 2.0 0.052 13.5 0.1 2.1 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CCU98953.1 - 0.063 13.4 0.2 0.063 13.4 0.2 2.1 2 0 0 2 2 2 0 PHD-like zinc-binding domain efThoc1 PF11957.3 CCU98954.1 - 3.5e-63 213.7 0.0 2.7e-62 210.8 0.0 2.2 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor MCPVI PF02993.9 CCU98954.1 - 1.7 8.7 7.6 4.2 7.4 5.3 1.7 1 0 0 1 1 1 0 Minor capsid protein VI DUF4407 PF14362.1 CCU98954.1 - 7.6 5.3 7.5 13 4.5 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_S27 PF01599.14 CCU98956.1 - 7.8e-25 86.4 0.4 8.8e-25 86.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S27a IBR PF01485.16 CCU98956.1 - 0.0098 15.7 0.2 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 IBR domain Pkinase PF00069.20 CCU98957.1 - 1.9e-56 191.1 0.0 2.4e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU98957.1 - 3.1e-20 72.3 0.0 5.6e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L2_C PF03947.13 CCU98959.1 - 2.2e-43 147.1 0.5 8.7e-43 145.2 0.3 2.0 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCU98959.1 - 5.4e-26 90.3 0.1 1.1e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Skp1 PF01466.14 CCU98960.1 - 1.2e-37 127.7 0.4 2.3e-37 126.8 0.3 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CCU98960.1 - 1.4e-23 82.7 0.1 3.5e-23 81.4 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 CCU98960.1 - 0.0064 16.4 0.1 0.15 12.0 0.1 2.2 1 1 0 1 1 1 1 BTB/POZ domain G-patch PF01585.18 CCU98962.1 - 5.1e-11 42.1 3.1 1.4e-10 40.7 2.1 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CCU98962.1 - 0.005 16.6 1.7 0.005 16.6 1.2 3.6 2 1 0 2 2 1 1 DExH-box splicing factor binding site MIP-T3 PF10243.4 CCU98962.1 - 0.0053 15.2 38.9 0.009 14.5 27.0 1.4 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Dapper PF15268.1 CCU98962.1 - 0.11 11.2 19.8 0.13 11.0 13.7 1.0 1 0 0 1 1 1 0 Dapper Ycf1 PF05758.7 CCU98962.1 - 0.15 9.7 15.4 0.18 9.5 10.7 1.1 1 0 0 1 1 1 0 Ycf1 DUF1777 PF08648.7 CCU98962.1 - 0.28 10.8 25.3 1.3 8.7 16.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) NPR3 PF03666.8 CCU98962.1 - 0.35 9.3 17.1 0.47 8.9 11.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.1 CCU98962.1 - 0.35 10.5 16.7 0.53 9.9 11.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DHHW PF14286.1 CCU98962.1 - 0.7 9.1 7.8 0.92 8.7 5.4 1.3 1 0 0 1 1 1 0 DHHW protein DUF1510 PF07423.6 CCU98962.1 - 0.74 9.1 28.2 1.3 8.3 19.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 CCU98962.1 - 0.81 8.8 14.3 1.5 7.9 9.9 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain DDRGK PF09756.4 CCU98962.1 - 0.96 8.8 31.7 0.042 13.2 18.1 1.7 2 0 0 2 2 2 0 DDRGK domain TFIIF_alpha PF05793.7 CCU98962.1 - 1 7.6 34.6 1.5 7.0 24.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Zip PF02535.17 CCU98962.1 - 1.3 7.9 7.5 2.1 7.2 5.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Pox_Ag35 PF03286.9 CCU98962.1 - 1.7 8.1 24.4 3.1 7.2 16.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GAGA_bind PF06217.7 CCU98962.1 - 2 8.3 20.1 3.8 7.3 13.9 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Vfa1 PF08432.5 CCU98962.1 - 2.1 8.3 30.2 4 7.4 21.0 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.11 CCU98962.1 - 2.5 7.9 9.3 3.9 7.2 6.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TAF4 PF05236.9 CCU98962.1 - 2.6 7.2 28.5 4.3 6.5 19.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF2413 PF10310.4 CCU98962.1 - 3.5 6.3 24.2 5.3 5.7 16.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CDC45 PF02724.9 CCU98962.1 - 3.6 5.5 20.2 5 5.0 14.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Hex_IIIa PF02455.11 CCU98962.1 - 3.9 6.0 8.4 5.5 5.5 5.8 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) SAPS PF04499.10 CCU98962.1 - 7.8 5.0 13.5 10 4.6 9.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein polyprenyl_synt PF00348.12 CCU98963.1 - 5.9e-72 241.6 0.0 7.5e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CN_hydrolase PF00795.17 CCU98964.1 - 5.7e-27 94.2 0.0 1e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_S24 PF00717.18 CCU98965.1 - 2.4e-07 30.2 0.3 5.9e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.4 CCU98965.1 - 0.1 12.0 0.0 7.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 Fer2 PF00111.22 CCU98966.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain ICL PF00463.16 CCU98967.1 - 3.6e-181 602.9 0.0 4.3e-181 602.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CCU98967.1 - 4.1e-09 36.0 0.0 1.2e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase RNA_pol_Rpc4 PF05132.9 CCU98968.1 - 3.2e-19 69.2 0.0 3.2e-19 69.2 0.0 3.5 3 1 1 4 4 4 2 RNA polymerase III RPC4 DUF2408 PF10303.4 CCU98969.1 - 7.7e-47 158.7 1.6 3e-33 114.7 0.0 5.2 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) DUF1664 PF07889.7 CCU98969.1 - 0.36 10.6 4.2 1.8 8.3 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3782 PF12644.2 CCU98969.1 - 1.2 8.9 3.6 35 4.2 2.2 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) DUF972 PF06156.8 CCU98969.1 - 3.3 8.0 6.8 3.5 8.0 0.0 3.8 3 1 2 5 5 5 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 CCU98969.1 - 4.2 7.4 7.9 1.7 8.7 0.3 3.3 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 CCU98969.1 - 8.6 6.1 11.6 7.5 6.3 0.9 4.5 4 1 1 5 5 5 0 Laminin Domain II Bax1-I PF01027.15 CCU98970.1 - 3.7e-34 118.1 7.0 5.7e-34 117.5 4.8 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pex14_N PF04695.8 CCU98970.1 - 0.35 10.9 1.0 0.47 10.5 0.0 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Profilin PF00235.14 CCU98971.1 - 7.8e-41 138.9 0.0 8.6e-41 138.8 0.0 1.0 1 0 0 1 1 1 1 Profilin TIM PF00121.13 CCU98972.1 - 2.4e-94 314.9 0.4 2.7e-94 314.8 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase SBP_bac_10 PF07596.6 CCU98972.1 - 0.15 12.0 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) Spo12 PF05032.7 CCU98973.1 - 2.4e-07 30.2 3.3 4.9e-07 29.2 2.3 1.5 1 0 0 1 1 1 1 Spo12 family SnoaL_2 PF12680.2 CCU98973.1 - 0.0013 19.1 0.0 0.0019 18.5 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 CCU98973.1 - 0.037 14.2 0.0 0.064 13.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) AICARFT_IMPCHas PF01808.13 CCU98974.1 - 9.8e-107 356.6 0.0 1.7e-106 355.9 0.0 1.4 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CCU98974.1 - 6.4e-21 74.1 0.0 1.2e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Ribosomal_S11 PF00411.14 CCU98974.1 - 0.077 13.1 0.1 0.97 9.6 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S11 Mon1 PF03164.9 CCU98975.1 - 1.2e-37 129.5 0.0 1.6e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Radical_SAM PF04055.16 CCU98976.1 - 4.3e-12 46.5 0.0 6.3e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily ATP_bind_1 PF03029.12 CCU98977.1 - 1.2e-72 244.3 0.1 6.8e-66 222.1 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CCU98977.1 - 7.7e-07 28.7 0.0 4.2e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CCU98977.1 - 4.7e-06 26.7 0.2 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.18 CCU98977.1 - 1.9e-05 24.1 0.1 6.9e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 CCU98977.1 - 3.5e-05 23.7 0.0 0.00011 22.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CCU98977.1 - 4.1e-05 23.5 0.0 0.00012 22.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 CCU98977.1 - 5.9e-05 22.6 0.0 0.00029 20.3 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 CCU98977.1 - 0.00011 23.0 0.1 0.00034 21.4 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 CCU98977.1 - 0.00015 21.9 0.0 0.00039 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 CCU98977.1 - 0.00038 19.9 0.1 0.77 9.1 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 CCU98977.1 - 0.00042 19.6 0.1 0.0038 16.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_25 PF13481.1 CCU98977.1 - 0.00057 19.3 1.9 0.0078 15.6 1.3 2.6 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 CCU98977.1 - 0.00064 18.5 0.1 0.029 13.1 0.0 2.3 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 CCU98977.1 - 0.00089 19.7 0.0 0.25 11.8 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 CCU98977.1 - 0.0011 18.6 0.1 0.0024 17.5 0.1 1.6 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.17 CCU98977.1 - 0.0015 18.0 0.4 0.01 15.3 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.1 CCU98977.1 - 0.014 15.0 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCU98977.1 - 0.022 14.2 0.0 0.077 12.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 CCU98977.1 - 0.025 14.8 0.0 0.062 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCU98977.1 - 0.027 13.6 0.0 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 CCU98977.1 - 0.029 13.8 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MobB PF03205.9 CCU98977.1 - 0.05 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CCU98977.1 - 0.065 12.9 0.3 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain Arf PF00025.16 CCU98977.1 - 0.067 12.4 0.0 14 4.8 0.0 2.6 3 0 0 3 3 3 0 ADP-ribosylation factor family RNA_helicase PF00910.17 CCU98977.1 - 0.07 13.3 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Sec2p PF06428.6 CCU98977.1 - 0.085 12.7 0.4 0.15 11.8 0.3 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p NTPase_1 PF03266.10 CCU98977.1 - 0.089 12.4 0.0 0.67 9.6 0.0 2.1 2 0 0 2 2 2 0 NTPase DUF87 PF01935.12 CCU98977.1 - 0.098 12.4 0.9 0.15 11.8 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_5 PF07728.9 CCU98977.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 CCU98977.1 - 0.14 10.7 0.0 3.1 6.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.13 CCU98977.1 - 0.2 11.1 2.8 0.18 11.2 0.3 2.1 2 1 0 2 2 2 0 FtsK/SpoIIIE family ADH_N PF08240.7 CCU98978.1 - 2.4e-22 78.7 0.8 4.5e-22 77.8 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCU98978.1 - 8.5e-14 51.2 0.0 1.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCU98978.1 - 0.00023 20.3 0.1 0.00037 19.7 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 CCU98978.1 - 0.0012 18.6 0.4 0.0026 17.5 0.3 1.5 1 0 0 1 1 1 1 ThiF family ApbA PF02558.11 CCU98978.1 - 0.0024 17.3 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 CCU98978.1 - 0.0041 16.6 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 CCU98978.1 - 0.0082 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CCU98978.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CCU98978.1 - 0.046 13.3 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF202 PF02656.10 CCU98979.1 - 7.5e-13 48.4 0.7 1.1e-12 47.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) COX17 PF05051.8 CCU98980.1 - 9.6e-18 63.9 5.4 1.5e-17 63.2 3.8 1.3 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.7 CCU98980.1 - 0.011 15.5 1.1 0.018 14.8 0.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) Ribosomal_60s PF00428.14 CCU98981.1 - 6.1e-27 93.8 10.6 8.6e-27 93.3 7.3 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.2 CCU98981.1 - 0.32 11.9 2.6 0.57 11.1 1.8 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Trehalase PF01204.13 CCU98982.1 - 1.9e-162 541.5 0.3 2.4e-162 541.1 0.2 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CCU98982.1 - 7.1e-12 44.4 1.8 1.2e-11 43.6 1.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ALS_ss_C PF10369.4 CCU98983.1 - 8.2e-20 70.3 0.0 8.2e-17 60.7 0.0 2.5 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.20 CCU98983.1 - 7.5e-10 38.0 0.0 1.3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 CCU98983.1 - 4.6e-07 29.5 0.0 1.9e-06 27.5 0.0 2.1 3 0 0 3 3 3 1 ACT domain ACT_6 PF13740.1 CCU98983.1 - 0.091 12.4 0.1 0.43 10.3 0.0 2.2 2 1 0 2 2 2 0 ACT domain ACT_7 PF13840.1 CCU98983.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 ACT domain Ribosomal_S21 PF01165.15 CCU98985.1 - 4.9e-10 38.6 6.6 7.4e-10 38.1 3.9 1.8 2 0 0 2 2 2 1 Ribosomal protein S21 Rot1 PF10681.4 CCU98986.1 - 8e-10 38.4 6.1 1.1e-06 28.2 0.2 2.2 1 1 1 2 2 2 2 Chaperone for protein-folding within the ER, fungal DUF619 PF04768.8 CCU98987.1 - 4.1e-30 104.4 0.0 9.9e-19 67.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF619) MBOAT PF03062.14 CCU98988.1 - 1.3e-35 123.0 21.8 2.3e-35 122.2 15.0 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Clat_adaptor_s PF01217.15 CCU98989.1 - 9.2e-48 161.5 0.5 1.3e-47 161.1 0.4 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pcc1 PF09341.5 CCU98990.1 - 4.5e-14 52.2 0.1 5.8e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 PIF1 PF05970.9 CCU98991.1 - 6.6e-60 202.9 0.0 2.8e-47 161.4 0.1 2.1 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CCU98991.1 - 2.3e-17 63.2 0.0 4.4e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCU98991.1 - 2.5e-07 30.9 0.0 6.3e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCU98991.1 - 3.8e-05 23.7 0.1 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CCU98991.1 - 0.00035 20.2 0.1 0.00097 18.8 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CCU98991.1 - 0.0004 19.9 0.1 0.0065 16.0 0.0 2.5 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 CCU98991.1 - 0.00063 19.4 0.0 0.88 9.2 0.0 2.3 2 0 0 2 2 2 2 NTPase IstB_IS21 PF01695.12 CCU98991.1 - 0.0023 17.3 0.0 0.37 10.1 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 CCU98991.1 - 0.0031 17.3 0.0 0.009 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CCU98991.1 - 0.0033 17.1 0.0 0.0079 15.8 0.0 1.8 1 1 0 1 1 1 1 NACHT domain DEAD PF00270.24 CCU98991.1 - 0.0035 16.8 0.1 0.59 9.6 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 CCU98991.1 - 0.0039 16.2 0.0 0.0063 15.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 CCU98991.1 - 0.0092 15.7 0.0 0.041 13.5 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 CCU98991.1 - 0.011 15.1 0.0 0.058 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCU98991.1 - 0.012 15.8 0.1 0.029 14.5 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCU98991.1 - 0.013 15.2 0.1 0.11 12.2 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CCU98991.1 - 0.013 15.7 0.0 0.048 13.9 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_11 PF13086.1 CCU98991.1 - 0.015 14.8 0.0 3.7 7.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 CCU98991.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.7 1 1 0 1 1 1 0 RNA helicase DUF258 PF03193.11 CCU98991.1 - 0.035 13.2 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_32 PF13654.1 CCU98991.1 - 0.038 12.6 0.0 0.064 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CCU98991.1 - 0.042 12.9 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 CCU98991.1 - 0.044 12.6 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgK PF03308.11 CCU98991.1 - 0.049 12.3 0.1 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_10 PF12846.2 CCU98991.1 - 0.051 13.0 0.0 0.44 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain TrwB_AAD_bind PF10412.4 CCU98991.1 - 0.062 11.9 0.1 0.12 10.9 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.1 CCU98991.1 - 0.064 12.7 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 CCU98991.1 - 0.065 13.1 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CCU98991.1 - 0.071 12.3 0.0 0.26 10.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 CCU98991.1 - 0.086 11.9 0.0 0.2 10.8 0.0 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.14 CCU98991.1 - 0.099 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Helicase_RecD PF05127.9 CCU98991.1 - 0.13 11.9 0.3 0.42 10.2 0.2 1.8 1 1 0 1 1 1 0 Helicase UPF0079 PF02367.12 CCU98991.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Herpes_Helicase PF02689.9 CCU98991.1 - 0.23 9.1 0.2 3 5.4 0.1 2.3 3 0 0 3 3 3 0 Helicase IF-2B PF01008.12 CCU98992.1 - 1.7e-53 181.4 0.1 5.9e-53 179.6 0.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF2013 PF09431.5 CCU98993.1 - 5.8e-33 113.5 0.5 8.2e-33 113.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) CAS_CSE1 PF03378.10 CCU98993.1 - 0.0057 15.0 0.0 0.0099 14.2 0.0 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus ORC4_C PF14629.1 CCU98994.1 - 3.8e-32 111.3 0.8 6.2e-32 110.6 0.0 1.7 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 CCU98994.1 - 4.9e-06 26.6 2.5 5.9e-06 26.3 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain PAXNEB PF05625.6 CCU98995.1 - 1.8e-35 122.4 0.0 2e-25 89.4 0.0 3.1 3 0 0 3 3 3 3 PAXNEB protein PRTP PF01366.13 CCU98995.1 - 0.25 9.2 0.0 0.37 8.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein AAA PF00004.24 CCU98996.1 - 7.4e-44 149.1 0.0 1.5e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCU98996.1 - 7e-08 32.5 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCU98996.1 - 1.5e-06 27.9 0.0 7.8e-06 25.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCU98996.1 - 3.3e-06 27.2 0.1 0.00042 20.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCU98996.1 - 5e-06 26.6 0.1 2.6e-05 24.2 0.0 2.1 2 1 1 3 3 2 1 AAA ATPase domain AAA_19 PF13245.1 CCU98996.1 - 4.7e-05 23.0 0.2 0.00033 20.3 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 CCU98996.1 - 6.5e-05 23.7 0.0 0.00018 22.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCU98996.1 - 8.2e-05 21.7 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CCU98996.1 - 0.00045 19.6 0.0 0.00081 18.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CCU98996.1 - 0.00088 18.0 0.0 0.0016 17.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 CCU98996.1 - 0.0016 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCU98996.1 - 0.002 18.0 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCU98996.1 - 0.0024 17.0 0.0 0.005 15.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.11 CCU98996.1 - 0.0037 16.5 0.0 0.077 12.2 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.1 CCU98996.1 - 0.0038 17.1 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CCU98996.1 - 0.0042 16.7 0.0 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CCU98996.1 - 0.0075 15.6 0.1 0.099 12.0 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCU98996.1 - 0.008 16.4 0.0 0.026 14.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CCU98996.1 - 0.0085 15.2 0.1 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CCU98996.1 - 0.012 14.7 0.0 0.03 13.4 0.0 1.6 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 CCU98996.1 - 0.021 14.3 0.1 0.093 12.2 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF2072 PF09845.4 CCU98996.1 - 0.022 14.7 0.2 0.045 13.6 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) AAA_24 PF13479.1 CCU98996.1 - 0.024 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CCU98996.1 - 0.025 14.2 0.0 0.58 9.8 0.0 2.3 1 1 1 2 2 2 0 NACHT domain DUF815 PF05673.8 CCU98996.1 - 0.029 13.3 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 CCU98996.1 - 0.03 13.1 0.0 0.094 11.5 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 CCU98996.1 - 0.037 14.2 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 CCU98996.1 - 0.062 13.3 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 CCU98996.1 - 0.085 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.1 CCU98996.1 - 0.096 12.2 0.3 0.42 10.1 0.0 2.2 2 2 0 2 2 2 0 AAA domain DUF641 PF04859.7 CCU98996.1 - 0.11 12.2 0.4 0.24 11.1 0.3 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.14 CCU98996.1 - 0.19 9.5 0.2 0.27 9.0 0.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_11 PF13414.1 CCU98997.1 - 2.6e-10 39.7 0.3 1.5e-06 27.7 0.1 2.6 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CCU98997.1 - 0.013 15.3 3.1 0.28 11.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCU98997.1 - 0.016 14.7 2.3 8.1 6.2 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCU98997.1 - 0.03 14.5 0.2 0.64 10.3 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCU98997.1 - 1.1 10.0 5.1 9.1 7.0 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Dus PF01207.12 CCU98998.1 - 2.8e-53 180.7 0.0 4.1e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-DHHC PF01529.15 CCU98999.1 - 2.6e-39 134.4 0.5 2.6e-39 134.4 0.3 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase OAD_gamma PF04277.8 CCU98999.1 - 0.054 13.8 0.2 58 4.1 0.0 3.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain NicO PF03824.11 CCU98999.1 - 0.071 12.4 3.0 2.9 7.1 0.1 3.0 3 0 0 3 3 3 0 High-affinity nickel-transport protein UPF0233 PF06781.7 CCU98999.1 - 0.15 11.6 7.6 0.81 9.3 0.5 3.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) Nodulin-like PF06813.8 CCU99000.1 - 9.8e-22 77.4 6.1 2.4e-21 76.1 4.2 1.6 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 CCU99000.1 - 1e-19 70.5 11.5 5.2e-19 68.1 8.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-ZPR1 PF03367.8 CCU99001.1 - 7.2e-103 340.5 0.5 7.9e-50 168.1 0.0 3.1 3 0 0 3 3 3 3 ZPR1 zinc-finger domain HypA PF01155.14 CCU99001.1 - 0.00098 18.7 2.7 0.7 9.5 0.2 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 CCU99001.1 - 0.011 14.9 8.6 0.14 11.3 0.5 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CCU99001.1 - 0.06 12.8 10.6 0.45 10.0 0.1 4.1 3 1 1 4 4 4 0 zinc-ribbon domain DZR PF12773.2 CCU99001.1 - 0.16 11.7 7.9 5.6 6.8 0.4 3.3 2 2 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CCU99001.1 - 0.24 11.4 6.7 7.8 6.5 0.1 4.0 4 0 0 4 4 4 0 Zinc ribbon domain Elf1 PF05129.8 CCU99001.1 - 1.2 8.8 4.2 27 4.5 0.1 2.9 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2HC5 PF06221.8 CCU99001.1 - 2.5 7.8 7.3 28 4.5 0.0 3.9 4 0 0 4 4 4 0 Putative zinc finger motif, C2HC5-type OrfB_Zn_ribbon PF07282.6 CCU99001.1 - 4.5 6.9 8.5 7 6.3 0.1 3.1 4 0 0 4 4 4 0 Putative transposase DNA-binding domain UPF0160 PF03690.8 CCU99002.1 - 3.1e-118 394.8 0.0 3.4e-118 394.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF1604 PF07713.8 CCU99004.1 - 8.9e-39 131.1 1.4 2.1e-38 129.9 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 CCU99004.1 - 1.5e-06 27.9 3.2 1.7e-06 27.7 1.2 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CCU99004.1 - 0.013 15.2 1.7 0.042 13.6 0.4 2.5 2 1 0 2 2 2 0 DExH-box splicing factor binding site TP_methylase PF00590.15 CCU99005.1 - 3.1e-13 49.9 0.6 1.3e-12 47.9 0.1 2.2 1 1 1 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF1900 PF08954.6 CCU99006.1 - 8.5e-47 158.0 0.0 2.1e-45 153.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) WD40 PF00400.27 CCU99006.1 - 1.2e-15 56.6 1.2 0.00012 21.8 0.1 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1899 PF08953.6 CCU99006.1 - 7.2e-06 25.5 0.3 1.2e-05 24.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) VID27 PF08553.5 CCU99006.1 - 0.021 13.0 0.0 0.042 12.0 0.0 1.4 1 0 0 1 1 1 0 VID27 cytoplasmic protein IncA PF04156.9 CCU99006.1 - 0.068 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 IncA protein DUF2205 PF10224.4 CCU99006.1 - 0.071 12.6 0.5 0.16 11.5 0.1 1.7 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) FRD2 PF03197.8 CCU99006.1 - 0.11 13.0 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage FRD2 protein Nop25 PF09805.4 CCU99007.1 - 9.6e-18 64.5 10.1 9.6e-18 64.5 7.0 2.2 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) MAT1 PF06391.8 CCU99008.1 - 6.7e-36 123.7 27.0 8.4e-36 123.4 18.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_3 PF13920.1 CCU99008.1 - 0.069 12.8 1.1 0.1 12.2 0.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCU99008.1 - 0.15 12.1 1.6 0.24 11.4 1.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCU99008.1 - 0.26 11.0 0.9 0.43 10.3 0.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain CAF-1_p150 PF11600.3 CCU99008.1 - 1 8.6 27.7 1.5 8.1 19.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nop53 PF07767.6 CCU99008.1 - 1.6 7.5 27.0 2.3 7.1 18.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) UbiA PF01040.13 CCU99009.1 - 8.3e-27 94.0 23.8 1.1e-26 93.6 16.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family adh_short PF00106.20 CCU99010.1 - 2.7e-24 85.9 0.8 4.1e-24 85.3 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCU99010.1 - 2.1e-10 40.5 0.4 3.3e-10 39.9 0.3 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 CCU99010.1 - 0.0054 15.4 0.1 0.0073 15.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCU99010.1 - 0.033 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCU99010.1 - 0.083 12.8 0.3 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 NADH(P)-binding DASH_Dam1 PF08653.5 CCU99012.1 - 5.3e-22 77.3 0.4 7.5e-22 76.8 0.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Acylphosphatase PF00708.13 CCU99013.1 - 3.2e-17 62.4 0.0 3.3e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase Acyltransferase PF01553.16 CCU99014.1 - 7.7e-13 48.0 0.0 8.6e-06 25.2 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase UvrD-helicase PF00580.16 CCU99015.1 - 5.7e-37 127.6 0.0 2.4e-36 125.6 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 CCU99015.1 - 2.4e-13 49.6 0.3 4.8e-13 48.6 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCU99015.1 - 0.00048 19.7 0.1 0.00077 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCU99015.1 - 0.0015 18.1 0.0 0.0017 17.9 0.0 1.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCU99015.1 - 0.012 14.9 0.2 0.19 11.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCU99015.1 - 0.042 13.9 0.0 0.09 12.9 0.0 1.6 2 1 0 2 2 2 0 AAA domain XylR_N PF06505.6 CCU99015.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Activator of aromatic catabolism UvrD_C PF13361.1 CCU99016.1 - 1.2e-80 271.6 0.0 1.3e-80 271.4 0.0 1.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 CCU99016.1 - 2.4e-13 50.0 0.0 5.7e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CCU99016.1 - 0.0003 20.4 0.0 0.00068 19.2 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 CCU99016.1 - 0.042 13.2 0.0 0.44 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mito_carr PF00153.22 CCU99017.1 - 2.5e-51 171.3 3.3 1.9e-16 59.5 0.2 3.9 3 2 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S64 PF08192.6 CCU99018.1 - 7.5 4.7 9.6 9 4.4 6.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 PAP2 PF01569.16 CCU99019.1 - 2.3e-14 53.1 3.4 4.6e-14 52.1 2.3 1.5 1 0 0 1 1 1 1 PAP2 superfamily dCMP_cyt_deam_1 PF00383.17 CCU99019.1 - 0.00017 21.1 0.1 0.00074 19.1 0.1 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 CCU99019.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF212 PF02681.9 CCU99019.1 - 0.11 12.2 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family Peptidase_M20 PF01546.23 CCU99020.1 - 1.6e-31 109.2 0.0 2.5e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCU99020.1 - 1.1e-13 50.9 0.0 1.6e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF1207 PF06727.6 CCU99020.1 - 0.13 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) Telomere_Sde2 PF13019.1 CCU99023.1 - 3.1e-25 88.7 6.2 3.1e-25 88.7 4.3 1.7 2 0 0 2 2 2 1 Telomere stability and silencing Amidase PF01425.16 CCU99024.1 - 5.4e-60 203.4 2.3 2.9e-40 138.4 0.0 2.3 1 1 1 2 2 2 2 Amidase Mito_carr PF00153.22 CCU99025.1 - 3.8e-58 193.1 9.1 1.5e-19 69.4 0.2 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 CCU99025.1 - 0.045 14.1 2.6 1.9 8.8 0.4 2.5 2 0 0 2 2 2 0 YtxH-like protein Keratin PF02422.11 CCU99025.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.5 3 0 0 3 3 3 0 Keratin Nop52 PF05997.7 CCU99026.1 - 8e-39 133.3 0.0 1.5e-38 132.3 0.0 1.4 1 1 1 2 2 2 1 Nucleolar protein,Nop52 Dabb PF07876.7 CCU99027.1 - 4.5e-09 36.6 0.0 9.1e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain PIG-S PF10510.4 CCU99028.1 - 1.2e-87 294.8 0.1 6e-75 252.8 0.0 2.1 2 0 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Pex24p PF06398.6 CCU99029.1 - 3.1e-29 101.8 4.4 4.2e-29 101.4 3.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin ATP12 PF07542.6 CCU99030.1 - 1.1e-40 138.4 0.1 2e-40 137.5 0.1 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein TPR_11 PF13414.1 CCU99031.1 - 2.5e-12 46.2 3.3 4.9e-09 35.7 0.3 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CCU99031.1 - 3.7e-07 29.5 6.8 0.00013 21.5 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCU99031.1 - 4.4e-06 26.0 1.2 0.0024 17.3 0.1 2.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCU99031.1 - 0.055 14.1 0.2 0.055 14.1 0.2 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCU99031.1 - 0.06 14.0 5.7 0.27 11.9 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Cytidylate_kin2 PF13189.1 CCU99031.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family TPR_12 PF13424.1 CCU99031.1 - 0.16 11.8 2.7 4 7.4 0.2 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCU99031.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat NADH-u_ox-rdase PF10785.4 CCU99032.1 - 6.6e-34 116.0 0.6 9.2e-34 115.5 0.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 CCU99032.1 - 0.1 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF4172 PF13776.1 CCU99032.1 - 0.11 12.5 0.2 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) Oligomerisation PF02410.10 CCU99033.1 - 1.5e-09 37.8 0.2 3.1e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Oligomerisation domain Neugrin PF06413.6 CCU99033.1 - 2.1e-08 34.2 0.1 3.2e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 CCU99033.1 - 2e-06 27.8 0.5 3.6e-06 27.0 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_Tnp_ISL3 PF13542.1 CCU99033.1 - 0.051 12.7 0.4 0.13 11.4 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 SYS1 PF09801.4 CCU99034.1 - 4.7e-19 68.8 7.0 4.2e-17 62.4 3.7 2.2 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network Mannosyl_trans2 PF04188.8 CCU99035.1 - 2.5e-38 132.1 0.1 3.3e-38 131.7 0.1 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) PMT_2 PF13231.1 CCU99035.1 - 0.0016 18.3 8.0 0.0016 18.3 5.5 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.13 CCU99035.1 - 0.0049 16.2 8.7 0.0091 15.3 6.1 1.5 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase GSAP-16 PF14959.1 CCU99035.1 - 0.13 11.9 0.2 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term SRP54 PF00448.17 CCU99036.1 - 8e-76 253.8 0.1 1.5e-75 253.0 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CCU99036.1 - 8.2e-25 87.0 16.0 1.9e-24 85.8 0.6 3.9 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.14 CCU99036.1 - 3.1e-11 43.1 0.2 7.8e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 CCU99036.1 - 3e-06 27.1 0.2 1.5e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CCU99036.1 - 5.6e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 CCU99036.1 - 0.00012 22.2 0.1 0.00052 20.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain cobW PF02492.14 CCU99036.1 - 0.00031 20.2 0.1 0.0014 18.1 0.0 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CCU99036.1 - 0.0019 17.0 1.1 0.053 12.3 0.0 2.9 2 1 0 2 2 2 1 ArgK protein EcsC PF12787.2 CCU99036.1 - 0.002 17.5 0.3 0.005 16.2 0.0 1.8 2 0 0 2 2 2 1 EcsC protein family CbiA PF01656.18 CCU99036.1 - 0.0023 17.3 0.1 0.012 15.0 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CCU99036.1 - 0.0057 16.5 0.1 0.72 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RAI16-like PF10257.4 CCU99036.1 - 0.0069 15.3 0.0 0.0099 14.8 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein AAA_10 PF12846.2 CCU99036.1 - 0.0083 15.6 0.0 0.03 13.7 0.0 2.0 2 1 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 CCU99036.1 - 0.0089 16.3 0.0 0.064 13.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain LigB PF02900.13 CCU99036.1 - 0.012 14.6 0.3 0.024 13.6 0.0 1.6 2 0 0 2 2 2 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase APS_kinase PF01583.15 CCU99036.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 CCU99036.1 - 0.03 15.1 0.1 0.079 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 CCU99036.1 - 0.031 13.6 1.3 0.07 12.4 0.1 2.1 2 0 0 2 2 2 0 Thymidylate kinase SRPRB PF09439.5 CCU99036.1 - 0.045 12.9 4.2 3 7.0 0.1 3.8 3 1 0 4 4 4 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 CCU99036.1 - 0.073 12.5 1.2 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3052 PF11253.3 CCU99036.1 - 0.083 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) XPG_I PF00867.13 CCU99037.1 - 4.8e-15 55.4 0.0 8.1e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CCU99037.1 - 0.00052 20.2 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Ribosomal_L10 PF00466.15 CCU99038.1 - 0.042 13.7 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L10 F-box-like PF12937.2 CCU99039.1 - 3.9e-05 23.2 6.0 0.00012 21.6 4.1 2.0 1 0 0 1 1 1 1 F-box-like E1-E2_ATPase PF00122.15 CCU99040.1 - 2.7e-51 173.8 0.5 2.7e-51 173.8 0.3 1.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCU99040.1 - 5e-34 118.6 1.6 9.5e-34 117.6 1.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCU99040.1 - 1e-13 51.8 0.0 1.9e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCU99040.1 - 4.9e-05 23.0 0.3 0.0083 15.7 0.3 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DHOase PF12890.2 CCU99040.1 - 0.057 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Dihydro-orotase-like Ribosomal_L12 PF00542.14 CCU99041.1 - 7.2e-20 70.7 11.2 5.7e-19 67.8 5.3 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 CCU99041.1 - 0.009 16.3 8.2 0.009 16.3 5.7 2.7 2 1 0 2 2 2 1 60s Acidic ribosomal protein PBP_dimer PF03717.10 CCU99041.1 - 0.039 14.0 0.3 0.047 13.7 0.2 1.2 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain DUF2765 PF10963.3 CCU99041.1 - 0.061 13.2 1.5 0.066 13.1 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2765) AphA_like PF14557.1 CCU99041.1 - 0.067 12.7 0.3 0.089 12.3 0.2 1.5 1 1 0 1 1 1 0 Putative AphA-like transcriptional regulator ERG4_ERG24 PF01222.12 CCU99042.1 - 4.6e-127 424.1 22.8 5.4e-127 423.9 15.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1569 PF07606.6 CCU99042.1 - 0.13 12.2 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) Syja_N PF02383.13 CCU99043.1 - 6.3e-87 291.3 0.0 1.3e-86 290.3 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain Proteasome PF00227.21 CCU99044.1 - 5.1e-52 175.9 0.2 6.6e-52 175.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Homoserine_dh PF00742.14 CCU99045.1 - 2.7e-46 157.5 0.0 5.2e-46 156.5 0.0 1.5 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CCU99045.1 - 4.4e-16 59.3 0.0 8.2e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 CCU99045.1 - 5.6e-05 23.4 0.1 0.00016 21.9 0.1 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.17 CCU99046.1 - 6.7e-76 255.6 0.0 1.4e-75 254.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 YbjN PF10722.4 CCU99046.1 - 0.073 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator NUDIX PF00293.23 CCU99047.1 - 5.5e-11 42.2 0.0 1.4e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain NUP PF06516.6 CCU99048.1 - 9.3e-71 238.2 1.0 5.5e-67 225.8 0.1 2.1 1 1 1 2 2 2 2 Purine nucleoside permease (NUP) FAD_binding_8 PF08022.7 CCU99049.1 - 3.8e-16 58.8 0.1 6e-15 55.0 0.0 2.3 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 CCU99049.1 - 5.2e-14 52.4 12.2 1.6e-13 50.8 8.4 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CCU99049.1 - 7.2e-14 51.9 0.0 2.8e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 CCU99049.1 - 0.0083 16.6 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DEAD PF00270.24 CCU99050.1 - 4.2e-35 120.7 0.2 6.8e-35 120.0 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU99050.1 - 4.4e-22 77.7 0.2 9.4e-12 44.6 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CCU99050.1 - 0.00024 20.9 0.0 0.00074 19.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DHHA2 PF02833.9 CCU99051.1 - 5.7e-12 45.9 0.0 8.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 CCU99051.1 - 1.2e-09 38.0 0.0 2.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 DHH family TPR_11 PF13414.1 CCU99052.1 - 1.7e-20 72.4 14.2 1.3e-11 43.9 0.1 3.8 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 CCU99052.1 - 7.5e-19 66.4 0.6 2e-06 27.1 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCU99052.1 - 7.7e-19 66.0 8.2 8e-05 22.2 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCU99052.1 - 8.5e-12 43.9 0.0 0.0029 17.2 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCU99052.1 - 4.8e-11 43.0 13.5 7.9e-09 35.9 0.2 6.2 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCU99052.1 - 2.7e-10 40.0 13.7 0.00021 21.1 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCU99052.1 - 4.6e-10 38.8 3.2 0.0036 17.3 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCU99052.1 - 1.6e-09 37.5 20.8 0.00031 21.1 0.1 6.9 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_20 PF14561.1 CCU99052.1 - 6.8e-07 29.3 9.9 0.0019 18.2 0.2 5.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCU99052.1 - 9.2e-05 21.9 6.8 3.9 7.5 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCU99052.1 - 0.00011 22.3 3.5 9.5 6.9 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCU99052.1 - 0.00013 22.2 16.9 0.047 14.0 0.5 5.0 3 2 4 7 7 6 4 Tetratricopeptide repeat Apc3 PF12895.2 CCU99052.1 - 0.00036 20.5 2.4 0.41 10.8 0.1 2.6 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Taxilin PF09728.4 CCU99052.1 - 0.017 14.2 2.9 0.028 13.5 2.0 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein RPN7 PF10602.4 CCU99052.1 - 0.02 14.2 0.3 0.15 11.4 0.0 2.5 2 1 0 2 2 2 0 26S proteasome subunit RPN7 Coatomer_E PF04733.9 CCU99052.1 - 0.026 13.7 0.2 4.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_9 PF13371.1 CCU99052.1 - 8.6 6.3 15.3 0.29 10.9 1.7 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat Pro_isomerase PF00160.16 CCU99053.1 - 2.9e-39 134.7 0.0 4.8e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 CCU99053.1 - 6.5e-06 25.5 0.1 3.5e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 CCU99053.1 - 0.0015 18.4 0.1 0.046 13.6 0.0 2.7 2 0 0 2 2 2 1 U-box domain Vps39_2 PF10367.4 CCU99054.1 - 8.6e-06 25.8 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 CCU99054.1 - 0.0071 16.3 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.12 CCU99054.1 - 0.078 12.9 2.7 4.9 7.3 0.3 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCU99054.1 - 0.4 10.6 6.0 9.2 6.3 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PolyA_pol PF01743.15 CCU99055.1 - 9.1e-22 77.6 0.0 1.5e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 CCU99055.1 - 1.8e-06 27.3 0.0 5.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Pkinase PF00069.20 CCU99056.1 - 1.1e-65 221.4 0.0 1.3e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99056.1 - 9.4e-32 110.0 0.0 2.1e-31 108.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU99056.1 - 2.5e-08 33.2 0.0 2.5e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CCU99056.1 - 0.0018 17.3 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCU99056.1 - 0.013 15.2 2.0 0.21 11.2 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family UAA PF08449.6 CCU99057.1 - 3.5e-55 187.0 16.7 1.8e-53 181.4 11.6 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CCU99057.1 - 3.9e-06 26.9 22.9 4.4e-06 26.7 2.2 3.2 2 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 CCU99057.1 - 0.0011 18.6 18.6 0.0036 16.9 6.5 3.0 2 1 0 2 2 2 2 Triose-phosphate Transporter family Borrelia_P13 PF05628.7 CCU99057.1 - 0.0025 17.6 1.0 0.022 14.5 0.4 2.4 2 0 0 2 2 2 1 Borrelia membrane protein P13 EmrE PF13536.1 CCU99057.1 - 0.0053 16.9 19.6 0.011 15.9 2.1 2.9 2 1 0 3 3 3 2 Multidrug resistance efflux transporter DUF914 PF06027.7 CCU99057.1 - 0.0071 15.2 9.5 0.073 11.9 0.1 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) Nuc_sug_transp PF04142.10 CCU99057.1 - 0.18 10.8 14.3 0.037 13.1 0.7 2.3 2 0 0 2 2 2 0 Nucleotide-sugar transporter DAP3 PF10236.4 CCU99058.1 - 1.5e-48 165.3 0.0 1.8e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CCU99058.1 - 5.1e-09 36.3 0.9 1e-08 35.4 0.6 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CCU99058.1 - 0.00059 19.5 0.0 0.0034 17.1 0.0 2.4 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CCU99058.1 - 0.0011 18.4 0.0 0.0027 17.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CCU99058.1 - 0.0026 17.2 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain IstB_IS21 PF01695.12 CCU99058.1 - 0.0042 16.5 0.0 0.0094 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 CCU99058.1 - 0.018 15.1 0.1 0.21 11.7 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CCU99058.1 - 0.023 14.3 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 CCU99058.1 - 0.072 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCU99058.1 - 0.073 12.7 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 CCU99058.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 CCU99058.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase G-alpha PF00503.15 CCU99058.1 - 0.14 10.7 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Arch_ATPase PF01637.13 CCU99058.1 - 0.18 11.4 0.0 0.43 10.2 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase DUF815 PF05673.8 CCU99058.1 - 0.19 10.6 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mob1_phocein PF03637.12 CCU99059.1 - 1.2e-54 184.6 2.1 1.5e-54 184.3 1.4 1.1 1 0 0 1 1 1 1 Mob1/phocein family FHA PF00498.21 CCU99060.1 - 4.5e-05 23.4 0.0 9.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain GTP_EFTU PF00009.22 CCU99061.1 - 3.4e-45 153.7 0.0 7.9e-45 152.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CCU99061.1 - 1.3e-21 76.2 0.0 2.8e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CCU99061.1 - 6.4e-17 61.2 0.2 6.1e-16 58.0 0.1 2.3 1 1 0 1 1 1 1 Elongation factor G C-terminus RRM_1 PF00076.17 CCU99061.1 - 6e-12 45.0 0.0 3e-11 42.7 0.0 2.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU_D2 PF03144.20 CCU99061.1 - 5.6e-11 42.3 0.1 1.4e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RRM_6 PF14259.1 CCU99061.1 - 2.5e-10 40.1 0.0 3.1e-09 36.6 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99061.1 - 2.8e-06 27.0 0.0 7.9e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EFG_IV PF03764.13 CCU99061.1 - 3.2e-05 23.4 0.0 9e-05 22.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV DUF866 PF05907.8 CCU99062.1 - 3.5e-25 88.3 0.0 5e-25 87.8 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-DNA_Pol PF08996.5 CCU99062.1 - 0.0044 16.4 0.0 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger Cytochrome_C7 PF14522.1 CCU99062.1 - 0.051 13.2 0.1 0.09 12.4 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c7 Paired_CXXCH_1 PF09699.5 CCU99062.1 - 0.092 12.2 1.9 0.17 11.3 1.3 1.5 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF164 PF02591.10 CCU99062.1 - 0.11 12.3 1.0 0.24 11.2 0.7 1.6 1 1 0 1 1 1 0 Putative zinc ribbon domain CDP-OH_P_transf PF01066.16 CCU99063.1 - 3.4e-12 46.5 3.3 6.7e-12 45.6 2.3 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF4328 PF14219.1 CCU99063.1 - 0.051 12.8 0.3 0.11 11.8 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4328) Metallophos PF00149.23 CCU99064.1 - 8e-14 51.4 0.0 4e-06 26.3 0.0 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase GAT PF03127.9 CCU99064.1 - 0.00053 19.9 0.2 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 CCU99064.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 VHS domain Nop53 PF07767.6 CCU99065.1 - 2.8e-71 240.5 32.9 3.9e-71 240.0 22.8 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) FAD-oxidase_C PF02913.14 CCU99065.1 - 4e-26 91.8 2.3 4.9e-26 91.5 0.0 2.1 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCU99065.1 - 5.6e-25 87.4 3.5 9.6e-25 86.6 1.2 2.2 3 0 0 3 3 3 1 FAD binding domain HIG_1_N PF04588.8 CCU99065.1 - 0.00029 20.5 0.5 0.00073 19.2 0.4 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region OST3_OST6 PF04756.8 CCU99066.1 - 3e-12 46.3 6.5 7.3e-12 45.1 4.5 1.7 1 0 0 1 1 1 1 OST3 / OST6 family Ribosomal_L16 PF00252.13 CCU99067.1 - 1e-36 125.6 0.1 1.3e-36 125.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Pribosyltran PF00156.22 CCU99068.1 - 1.8e-15 56.7 0.2 3.1e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 CCU99068.1 - 0.033 13.4 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase WD40 PF00400.27 CCU99069.1 - 7.9e-60 196.7 18.3 3.1e-10 39.5 0.0 8.2 8 1 0 8 8 8 7 WD domain, G-beta repeat CLTH PF10607.4 CCU99069.1 - 0.13 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Cid2 PF09774.4 CCU99071.1 - 5.8e-23 81.6 0.9 7.5e-23 81.2 0.6 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 TRI9 PF08195.6 CCU99071.1 - 0.03 13.9 0.1 0.063 12.9 0.1 1.5 1 0 0 1 1 1 0 TRI9 protein NAD_Gly3P_dh_C PF07479.9 CCU99072.1 - 7.8e-49 165.2 0.0 1.3e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 CCU99072.1 - 4.1e-34 117.5 0.2 6.2e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus EI24 PF07264.6 CCU99074.1 - 6.8e-16 58.3 8.7 9.9e-16 57.8 6.0 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Glyco_hydro_3 PF00933.16 CCU99075.1 - 4.2e-83 278.7 0.0 6.4e-83 278.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CCU99075.1 - 2.5e-64 216.8 0.9 1.3e-63 214.5 0.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CCU99075.1 - 1.3e-19 69.9 0.1 2.4e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain NUDIX PF00293.23 CCU99076.1 - 6.2e-13 48.5 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DEAD PF00270.24 CCU99077.1 - 7.4e-43 145.9 0.0 1.4e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU99077.1 - 6.5e-22 77.1 0.0 1.4e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCU99077.1 - 0.00096 19.0 0.0 0.003 17.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF77 PF01910.12 CCU99078.1 - 2.3e-16 59.2 0.0 8.3e-16 57.4 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF77 Aminotran_3 PF00202.16 CCU99079.1 - 1.9e-84 283.4 0.0 2.6e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Mob1_phocein PF03637.12 CCU99080.1 - 4.8e-65 218.4 0.0 5.6e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family His_Phos_2 PF00328.17 CCU99081.1 - 2.7e-42 145.3 0.0 3.5e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GATase_2 PF00310.16 CCU99082.1 - 8.5e-22 77.3 0.6 2.6e-17 62.5 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCU99082.1 - 3.2e-15 56.2 0.0 7e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CCU99082.1 - 1.8e-12 47.0 0.0 5.5e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 CCU99082.1 - 6.4e-12 45.2 0.1 1.1e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 CCU99082.1 - 4.8e-05 22.1 0.0 0.00017 20.3 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Mito_carr PF00153.22 CCU99083.1 - 2.1e-60 200.4 1.5 2.1e-20 72.2 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Y_phosphatase2 PF03162.8 CCU99084.1 - 5.8e-49 165.6 0.0 8.4e-49 165.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Aldo_ket_red PF00248.16 CCU99084.1 - 1.9e-21 76.1 0.0 2.7e-16 59.2 0.0 2.3 2 1 0 2 2 2 2 Aldo/keto reductase family Y_phosphatase3 PF13350.1 CCU99084.1 - 0.00058 20.1 0.0 0.0031 17.7 0.0 1.9 1 1 0 2 2 2 1 Tyrosine phosphatase family Chitin_synth_1 PF01644.12 CCU99085.1 - 2.1e-63 213.0 0.0 3.1e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 CCU99085.1 - 4.2e-26 91.4 1.8 4.2e-21 74.9 0.0 2.6 2 1 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 CCU99085.1 - 2.2e-23 81.7 0.0 7.9e-23 79.9 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.1 CCU99085.1 - 7.3e-08 32.4 0.0 1.7e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CCU99085.1 - 1.5e-06 28.1 10.6 1.5e-06 28.1 7.3 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DASH_Ask1 PF08655.5 CCU99086.1 - 3.8e-28 97.0 0.5 7.2e-28 96.2 0.3 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 OTU PF02338.14 CCU99087.1 - 1.6e-17 64.2 0.1 9.3e-17 61.7 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CCU99087.1 - 0.0014 17.9 0.0 0.015 14.6 0.0 2.0 1 1 0 1 1 1 1 Peptidase C65 Otubain Actin PF00022.14 CCU99088.1 - 7.3e-113 376.9 0.0 1e-112 376.4 0.0 1.2 1 0 0 1 1 1 1 Actin Phosphoesterase PF04185.9 CCU99089.1 - 9.7e-73 245.5 4.2 1.5e-72 244.8 2.9 1.3 1 0 0 1 1 1 1 Phosphoesterase family MFS_1 PF07690.11 CCU99090.1 - 2.1e-20 72.7 32.1 7.6e-19 67.6 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.13 CCU99091.1 - 5.8e-14 51.9 6.0 8e-14 51.4 4.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.19 CCU99091.1 - 0.0032 16.8 0.0 0.0052 16.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AAA_11 PF13086.1 CCU99092.1 - 1.5e-48 165.4 0.3 2.2e-48 164.9 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 CCU99092.1 - 5.6e-45 153.1 0.0 8.2e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCU99092.1 - 2.6e-14 53.2 1.9 9.2e-09 35.1 0.5 2.9 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 CCU99092.1 - 6.8e-13 48.1 8.4 7.3e-12 44.8 1.7 4.0 3 0 0 3 3 3 1 Part of AAA domain UvrD-helicase PF00580.16 CCU99092.1 - 0.00067 19.0 0.4 0.0012 18.2 0.1 1.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 CCU99092.1 - 0.0052 16.3 0.2 3.2 7.2 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 CCU99092.1 - 0.031 13.4 0.0 0.068 12.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.1 CCU99092.1 - 0.049 13.7 0.1 0.22 11.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 CCU99092.1 - 0.069 12.0 0.1 5 5.9 0.0 2.4 3 0 0 3 3 3 0 PIF1-like helicase DUF2075 PF09848.4 CCU99092.1 - 0.12 11.3 0.1 0.24 10.3 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IATP PF04568.7 CCU99093.1 - 1.1e-13 51.0 0.2 1.2e-13 50.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF2639 PF11121.3 CCU99093.1 - 0.31 10.5 2.4 0.84 9.1 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2639) bZIP_2 PF07716.10 CCU99093.1 - 4.4 7.2 6.9 6.6 6.6 4.8 1.2 1 0 0 1 1 1 0 Basic region leucine zipper ATP_sub_h PF10775.4 CCU99094.1 - 2.2e-21 75.3 1.7 5e-21 74.1 0.8 1.8 2 0 0 2 2 2 1 ATP synthase complex subunit h Got1 PF04178.7 CCU99095.1 - 2.3e-06 27.7 0.5 2.6e-06 27.5 0.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1049 PF06305.6 CCU99095.1 - 0.066 12.7 0.1 0.086 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Phage_holin_5 PF06946.6 CCU99095.1 - 0.085 13.0 0.1 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 Phage holin eIF2_C PF09173.6 CCU99096.1 - 6.7e-38 128.6 0.1 1.5e-37 127.4 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.22 CCU99096.1 - 1.4e-35 122.4 0.0 2.6e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CCU99096.1 - 2.8e-12 46.5 0.6 2.8e-12 46.5 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCU99096.1 - 0.028 14.3 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCU99096.1 - 0.066 13.0 0.1 0.26 11.0 0.1 2.2 1 1 0 1 1 1 0 Dynamin family PPR_2 PF13041.1 CCU99097.1 - 1.2e-09 38.0 0.0 0.00022 21.1 0.0 3.2 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 CCU99097.1 - 8e-07 28.8 8.4 0.017 15.3 0.0 6.3 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 CCU99097.1 - 0.0028 17.5 0.0 0.81 9.8 0.0 3.3 4 0 0 4 4 4 1 PPR repeat CRC_subunit PF08624.5 CCU99098.1 - 1.6e-46 157.6 0.4 5e-46 156.0 0.1 1.9 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Evr1_Alr PF04777.8 CCU99100.1 - 1.6e-24 85.6 0.6 4.3e-24 84.2 0.1 1.8 2 0 0 2 2 2 1 Erv1 / Alr family COX16 PF14138.1 CCU99100.1 - 5.7e-11 42.4 1.0 8.7e-11 41.8 0.7 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 SET PF00856.23 CCU99101.1 - 8.9e-09 35.8 0.0 2.2e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 SET domain NST1 PF13945.1 CCU99102.1 - 9.9e-21 74.6 1.2 9.9e-21 74.6 0.8 4.7 3 1 1 4 4 4 2 Salt tolerance down-regulator MIP-T3 PF10243.4 CCU99102.1 - 0.22 9.9 83.5 0.075 11.4 52.2 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 zf-C2H2_2 PF12756.2 CCU99104.1 - 2.3e-36 123.9 13.0 2.2e-29 101.5 0.5 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CCU99104.1 - 3.1e-08 33.5 12.6 5.3e-06 26.4 2.9 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCU99104.1 - 3.2e-07 30.3 3.6 3.2e-07 30.3 2.5 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CCU99104.1 - 0.00053 19.7 2.8 0.00053 19.7 1.9 3.5 5 0 0 5 5 5 1 C2H2-type zinc finger zf-DBF PF07535.7 CCU99104.1 - 0.0041 16.7 0.7 0.0041 16.7 0.5 3.5 4 0 0 4 4 4 1 DBF zinc finger zf-C2H2 PF00096.21 CCU99104.1 - 0.028 14.7 3.4 0.028 14.7 2.3 3.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF4606 PF15379.1 CCU99104.1 - 0.082 12.9 0.3 0.082 12.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) zf-C2H2_4 PF13894.1 CCU99104.1 - 0.21 12.0 6.6 0.19 12.1 1.7 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.7 CCU99104.1 - 0.43 9.0 5.7 2.1 6.7 0.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF629) MRP-L28 PF09812.4 CCU99104.1 - 0.71 9.6 5.3 0.35 10.6 0.9 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 AKAP95 PF04988.7 CCU99104.1 - 5.5 6.7 9.9 10 5.8 1.6 2.7 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) CDC45 PF02724.9 CCU99104.1 - 8 4.3 17.3 0.17 9.8 0.8 2.1 2 0 0 2 2 2 0 CDC45-like protein RRM_6 PF14259.1 CCU99105.1 - 7.4e-13 48.2 0.0 6.8e-08 32.3 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99105.1 - 4.1e-10 39.3 0.1 2.8e-07 30.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCU99105.1 - 1e-08 34.6 0.0 0.0027 17.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCU99105.1 - 6.6e-08 32.2 0.0 0.0047 16.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.12 CCU99105.1 - 8.4e-06 25.8 0.0 2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 CCU99105.1 - 0.00024 20.7 0.1 0.0005 19.6 0.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 CCU99105.1 - 0.038 13.8 0.0 0.75 9.6 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif Ribosomal_L18ae PF01775.12 CCU99106.1 - 6.1e-57 190.8 1.8 7.4e-57 190.6 1.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Vps35 PF03635.12 CCU99107.1 - 3.4e-299 994.3 0.2 4e-299 994.1 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 E1-E2_ATPase PF00122.15 CCU99108.1 - 1.2e-22 80.1 0.0 2.3e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCU99108.1 - 4e-10 40.4 0.1 4.2e-09 37.1 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCU99108.1 - 1.2e-08 34.7 0.0 4.5e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCU99108.1 - 8.4e-08 32.6 0.0 2.3e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Afaf PF15339.1 CCU99108.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Acrosome formation-associated factor RRM_1 PF00076.17 CCU99109.1 - 5.9e-13 48.2 0.0 1.3e-12 47.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99109.1 - 2.6e-12 46.5 0.0 4.4e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99109.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) THF_DHG_CYH PF00763.18 CCU99110.1 - 1e-17 64.2 0.0 5.1e-15 55.5 0.0 2.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 CCU99110.1 - 3.6e-13 48.9 0.0 6.7e-08 31.7 0.0 3.0 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 CCU99110.1 - 0.00061 18.7 0.1 0.00086 18.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Shikimate_DH PF01488.15 CCU99110.1 - 0.031 14.3 0.0 1.3 9.1 0.0 2.2 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase SNARE PF05739.14 CCU99111.1 - 1.1e-17 63.3 3.5 4.9e-17 61.3 2.4 2.2 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.1 CCU99111.1 - 1.2e-16 60.5 9.3 1.6e-16 60.1 1.3 3.6 3 0 0 3 3 3 1 Syntaxin-like protein TAF PF02969.12 CCU99111.1 - 1.9e-14 53.3 0.0 5.7e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 CCU99111.1 - 4.3e-12 45.9 0.0 1.5e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) Syntaxin PF00804.20 CCU99111.1 - 0.026 14.6 7.0 0.35 11.0 4.9 2.8 1 1 0 1 1 1 0 Syntaxin Spectrin PF00435.16 CCU99111.1 - 0.33 11.2 7.1 6 7.2 2.5 2.5 2 0 0 2 2 2 0 Spectrin repeat DnaJ PF00226.26 CCU99113.1 - 5.1e-25 86.9 0.8 8.4e-25 86.2 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCU99113.1 - 4.9e-17 61.5 0.0 3e-15 55.8 0.0 2.5 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCU99113.1 - 4.8e-12 45.7 23.3 8.2e-12 45.0 16.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 CCU99113.1 - 0.011 16.0 7.8 0.022 15.0 5.4 1.5 1 0 0 1 1 1 0 Cytochrome c3 HypA PF01155.14 CCU99113.1 - 0.91 9.2 8.4 6.9 6.3 1.9 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Lyase_1 PF00206.15 CCU99114.1 - 8.2e-97 324.1 0.0 1.1e-96 323.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 CCU99114.1 - 2.8e-29 100.9 0.0 5.5e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Calreticulin PF00262.13 CCU99115.1 - 1.2e-150 501.2 9.0 1.5e-150 500.9 6.2 1.1 1 0 0 1 1 1 1 Calreticulin family Peptidase_S8 PF00082.17 CCU99116.1 - 8.3e-55 185.9 1.6 1.2e-54 185.4 1.1 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CCU99116.1 - 1.1e-23 82.8 0.1 2e-23 81.9 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF3592 PF12158.3 CCU99116.1 - 0.048 13.4 0.1 0.98 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) LuxS PF02664.10 CCU99116.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) DUF2970 PF11174.3 CCU99116.1 - 0.091 12.3 0.7 0.19 11.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DUF2407_C PF13373.1 CCU99117.1 - 1.9e-10 40.8 8.8 3e-10 40.1 2.1 3.0 1 1 1 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.4 CCU99117.1 - 0.00021 21.4 0.0 0.0007 19.7 0.0 1.9 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain SNF2_N PF00176.18 CCU99118.1 - 4.4e-80 268.6 0.1 7e-80 268.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 CCU99118.1 - 3.9e-39 133.0 0.1 1.9e-38 130.7 0.1 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 CCU99118.1 - 2e-28 99.0 10.0 2.5e-28 98.7 3.4 3.2 2 0 0 2 2 2 1 HAND Helicase_C PF00271.26 CCU99118.1 - 2.5e-14 52.8 0.0 2.7e-13 49.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CCU99118.1 - 9e-10 37.8 0.0 2.2e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CCU99118.1 - 1.9e-07 30.7 0.0 4.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CCU99118.1 - 5.9e-07 29.4 0.0 4.2e-06 26.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DBINO PF13892.1 CCU99118.1 - 0.00011 22.2 0.4 0.00011 22.2 0.3 3.7 4 0 0 4 4 4 1 DNA-binding domain Myb_DNA-binding PF00249.26 CCU99118.1 - 0.027 14.5 0.0 0.17 11.9 0.0 2.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DEAD_2 PF06733.10 CCU99118.1 - 0.03 13.7 0.0 0.073 12.4 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 CCU99118.1 - 0.033 14.0 2.7 0.049 13.5 0.0 2.7 4 0 0 4 4 3 0 AAA domain HEAT PF02985.17 CCU99119.1 - 2.5e-16 58.2 16.5 0.0006 19.6 0.0 10.3 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.1 CCU99119.1 - 2.1e-15 56.7 19.4 8.3e-07 29.3 0.0 9.8 11 0 0 11 11 11 3 HEAT-like repeat HEAT_2 PF13646.1 CCU99119.1 - 7.2e-11 42.2 16.7 8.3e-06 26.0 0.0 7.0 3 2 3 7 7 7 4 HEAT repeats IBN_N PF03810.14 CCU99119.1 - 1e-10 41.3 0.1 2.7e-09 36.7 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3731 PF12531.3 CCU99119.1 - 0.016 14.7 0.1 0.12 11.9 0.1 2.4 2 0 0 2 2 2 0 DNA-K related protein ParcG PF10274.4 CCU99119.1 - 0.017 15.0 0.0 0.085 12.7 0.0 2.2 1 0 0 1 1 1 0 Parkin co-regulated protein MMS19_N PF14500.1 CCU99119.1 - 0.025 13.8 1.1 4.2 6.5 0.0 2.9 2 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Arm PF00514.18 CCU99119.1 - 0.028 14.2 8.2 1.8 8.4 0.3 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 CCU99119.1 - 0.051 13.2 3.4 4.7 6.8 0.0 4.1 4 2 0 4 4 4 0 rRNA processing/ribosome biogenesis DUF383 PF04063.9 CCU99119.1 - 0.057 12.9 0.2 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF383) DAHP_synth_1 PF00793.15 CCU99120.1 - 3.7e-93 311.1 0.0 4.5e-93 310.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COG7 PF10191.4 CCU99121.1 - 6.4e-31 107.0 0.0 2.4e-23 81.9 0.0 2.1 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) FlaF PF07309.6 CCU99121.1 - 4.5 7.1 7.9 0.67 9.8 0.4 3.0 2 1 0 3 3 3 0 Flagellar protein FlaF Ldh_1_N PF00056.18 CCU99122.1 - 1.8e-43 147.7 0.1 2.7e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CCU99122.1 - 5.9e-40 136.8 0.2 2.4e-39 134.8 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CCU99122.1 - 9.3e-05 21.2 0.0 0.00014 20.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCU99122.1 - 0.018 14.4 0.0 0.041 13.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CCU99122.1 - 0.092 13.0 0.5 1.4 9.2 0.0 2.7 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 CCU99122.1 - 0.12 11.6 0.2 0.27 10.5 0.1 1.5 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase AAA PF00004.24 CCU99123.1 - 1.6e-58 196.6 0.0 5.7e-44 149.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCU99123.1 - 5.2e-08 33.0 12.3 0.0054 16.7 0.3 5.6 3 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 CCU99123.1 - 9.4e-06 25.7 0.2 0.0069 16.5 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCU99123.1 - 2.1e-05 24.2 0.3 0.0055 16.4 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CCU99123.1 - 3.6e-05 24.5 0.0 0.011 16.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 CCU99123.1 - 0.00041 19.3 0.1 0.64 8.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 CCU99123.1 - 0.00042 19.7 0.2 0.0017 17.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 CCU99123.1 - 0.00048 19.8 7.1 0.0018 17.9 0.0 3.8 4 0 0 4 4 2 1 Part of AAA domain RuvB_N PF05496.7 CCU99123.1 - 0.00068 18.7 0.0 0.0035 16.4 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CCU99123.1 - 0.00083 19.0 1.9 0.92 9.1 0.0 3.4 3 1 1 4 4 4 1 NACHT domain AAA_25 PF13481.1 CCU99123.1 - 0.00086 18.7 4.0 0.0098 15.3 0.3 3.7 2 2 1 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 CCU99123.1 - 0.0014 18.7 0.0 0.97 9.4 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 CCU99123.1 - 0.0016 18.2 0.0 0.14 12.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CCU99123.1 - 0.0026 16.9 0.1 0.0062 15.6 0.0 1.6 2 0 0 2 2 1 1 KaiC AAA_28 PF13521.1 CCU99123.1 - 0.0034 17.3 0.0 0.095 12.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 CCU99123.1 - 0.004 16.0 0.0 0.0069 15.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.9 CCU99123.1 - 0.004 17.0 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CCU99123.1 - 0.0063 15.7 0.5 0.034 13.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCU99123.1 - 0.0089 15.5 0.0 0.65 9.4 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 CCU99123.1 - 0.011 15.6 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CCU99123.1 - 0.013 15.7 0.0 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CCU99123.1 - 0.015 14.8 0.3 0.024 14.2 0.2 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CCU99123.1 - 0.016 14.8 0.0 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 CCU99123.1 - 0.023 13.4 0.1 0.07 11.8 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus PhoH PF02562.11 CCU99123.1 - 0.024 13.8 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 CCU99123.1 - 0.035 14.2 0.0 0.093 12.9 0.0 1.7 2 0 0 2 2 1 0 RNA helicase T2SE PF00437.15 CCU99123.1 - 0.056 12.3 0.0 3.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 CCU99123.1 - 0.064 12.3 0.0 0.58 9.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 CCU99123.1 - 0.076 12.5 0.4 12 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_3 PF07726.6 CCU99123.1 - 0.14 11.7 0.0 0.45 10.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 CCU99123.1 - 0.28 10.0 0.0 1.3 7.7 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 CCU99123.1 - 0.41 10.3 0.0 3.6 7.2 0.0 2.1 2 0 0 2 2 2 0 NTPase Arch_ATPase PF01637.13 CCU99123.1 - 0.68 9.5 0.1 13 5.4 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase STT3 PF02516.9 CCU99124.1 - 1.2e-131 440.0 33.5 1.8e-131 439.4 23.2 1.2 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 CCU99124.1 - 0.00043 20.2 14.7 0.00043 20.2 10.2 3.6 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF3405 PF11885.3 CCU99125.1 - 3e-128 428.2 8.9 1.9e-125 418.9 6.2 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Cellsynth_D PF03500.8 CCU99126.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Cellulose synthase subunit D Thioredoxin PF00085.15 CCU99127.1 - 8.9e-28 96.0 0.0 3.5e-26 90.8 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 CCU99127.1 - 4.4e-09 36.5 0.1 1.8e-08 34.5 0.1 2.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CCU99127.1 - 6.3e-05 22.9 0.3 0.00072 19.5 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_8 PF13905.1 CCU99127.1 - 0.00035 20.6 0.0 0.013 15.5 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CCU99127.1 - 0.097 12.2 0.0 0.38 10.3 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin APG6 PF04111.7 CCU99127.1 - 4.2 6.3 9.0 8.8 5.2 6.2 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Prenyltrans PF00432.16 CCU99128.1 - 2.6e-31 106.8 15.4 5.2e-08 32.3 0.0 6.3 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCU99128.1 - 8.1e-22 77.7 0.0 1.8e-16 60.5 0.0 3.3 2 1 0 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCU99128.1 - 0.00015 21.7 0.0 0.0045 16.9 0.0 3.1 2 1 1 3 3 3 2 Prenyltransferase-like MDMPI_N PF11716.3 CCU99130.1 - 6.7 7.1 19.3 0.45 10.9 6.2 2.2 1 1 1 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Cyclin_N PF00134.18 CCU99131.1 - 1.1e-43 147.7 0.1 2.3e-43 146.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCU99131.1 - 1.4e-24 86.3 0.0 2.3e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain TatD_DNase PF01026.16 CCU99132.1 - 1.5e-22 80.0 0.0 1.7e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase NTF2 PF02136.15 CCU99134.1 - 1.6e-27 96.2 0.7 2.3e-27 95.6 0.5 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 CCU99134.1 - 1.1e-07 31.3 0.3 2.2e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99134.1 - 0.0001 22.2 0.1 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99134.1 - 0.00013 21.7 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MCPVI PF02993.9 CCU99134.1 - 8.4 6.4 8.3 16 5.5 5.7 1.4 1 0 0 1 1 1 0 Minor capsid protein VI RHD3 PF05879.7 CCU99135.1 - 1.4e-230 767.1 0.0 6.1e-230 765.0 0.0 1.7 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.18 CCU99135.1 - 3.9e-05 23.5 0.0 7.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.14 CCU99135.1 - 6.7e-05 22.0 0.1 0.00015 20.8 0.0 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 CCU99135.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 CCU99135.1 - 0.0017 18.3 0.2 0.0065 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CCU99135.1 - 0.0019 18.6 0.0 0.0042 17.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Hpt PF01627.18 CCU99135.1 - 0.0079 16.1 1.5 0.037 14.0 0.1 2.7 2 0 0 2 2 2 1 Hpt domain DUF2523 PF10734.4 CCU99135.1 - 0.029 14.6 0.1 0.084 13.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) DPBB_1 PF03330.13 CCU99136.1 - 3.3e-08 33.4 0.0 4.6e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel zf-TFIIB PF13453.1 CCU99136.1 - 0.00088 18.4 0.8 0.0023 17.0 0.1 2.1 2 0 0 2 2 2 1 Transcription factor zinc-finger Cerato-platanin PF07249.7 CCU99136.1 - 0.014 15.3 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Cerato-platanin Ank PF00023.25 CCU99137.1 - 4.1e-15 54.7 3.1 8e-07 28.5 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 CCU99137.1 - 5.4e-13 48.7 5.0 1.3e-12 47.5 2.2 2.7 3 0 0 3 3 3 1 IPT/TIG domain Ank_2 PF12796.2 CCU99137.1 - 2.7e-12 46.8 0.1 5e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCU99137.1 - 1.5e-10 41.2 1.1 6.4e-07 29.7 1.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCU99137.1 - 3.8e-08 33.3 1.6 2.6e-07 30.6 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCU99137.1 - 9.7e-08 31.5 1.4 0.0019 18.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Glyco_transf_22 PF03901.12 CCU99138.1 - 6.1e-63 213.2 14.1 3.1e-40 138.4 3.5 2.0 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family CR6_interact PF10147.4 CCU99138.1 - 0.13 11.5 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 AAA PF00004.24 CCU99139.1 - 1.1e-12 48.2 0.0 2.4e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCU99139.1 - 7.5e-09 35.8 0.7 3.8e-07 30.2 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCU99139.1 - 5.6e-07 29.7 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCU99139.1 - 0.01 15.5 0.3 0.04 13.6 0.2 2.0 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 CCU99139.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 CCU99139.1 - 0.041 13.4 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cdc6_C PF09079.6 CCU99139.1 - 0.088 12.5 0.0 0.37 10.5 0.0 2.1 2 1 0 2 2 2 0 CDC6, C terminal DUF2075 PF09848.4 CCU99139.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MTHFR PF02219.12 CCU99140.1 - 5.8e-97 324.2 0.0 3.8e-96 321.5 0.0 1.9 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase PDCD2_C PF04194.8 CCU99140.1 - 3.5e-28 98.2 0.9 1.3e-27 96.4 0.0 2.4 1 1 1 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Glutaredoxin PF00462.19 CCU99141.1 - 2.3e-17 62.7 0.0 3.2e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin zf-C2H2 PF00096.21 CCU99142.1 - 2.1e-06 27.6 12.0 0.00064 19.9 1.3 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCU99142.1 - 0.00011 22.3 8.0 0.026 14.8 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCU99142.1 - 0.018 14.8 2.7 1 9.3 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCU99142.1 - 0.048 13.9 0.8 0.048 13.9 0.6 2.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2HC_2 PF13913.1 CCU99142.1 - 1 9.0 8.0 0.23 11.1 1.8 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type V-SNARE_C PF12352.3 CCU99143.1 - 1.2e-08 34.8 1.0 2.7e-08 33.7 0.2 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CCU99143.1 - 0.0015 18.2 0.2 0.006 16.2 0.0 2.1 2 1 1 3 3 3 1 Sec20 Use1 PF09753.4 CCU99143.1 - 0.069 12.5 0.3 0.093 12.1 0.2 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 RasGAP_C PF03836.10 CCU99143.1 - 0.071 12.7 0.1 0.66 9.6 0.0 2.1 2 0 0 2 2 2 0 RasGAP C-terminus Asparaginase_2 PF01112.13 CCU99143.1 - 0.075 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Asparaginase DUF4035 PF13227.1 CCU99143.1 - 0.12 11.7 0.5 8.8 5.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4035) CRM1_C PF08767.6 CCU99144.1 - 2.7e-128 427.3 2.1 2.7e-127 424.1 0.0 3.5 3 2 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 CCU99144.1 - 2.8e-39 134.4 0.4 2.8e-39 134.4 0.3 3.6 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 CCU99144.1 - 5.4e-14 51.8 1.1 2.7e-13 49.6 0.8 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Zn_peptidase PF04228.8 CCU99144.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Ank_2 PF12796.2 CCU99145.1 - 1.2e-38 131.2 11.2 1.7e-17 63.4 1.0 4.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 CCU99145.1 - 9.7e-30 100.8 11.7 6.4e-07 28.8 0.0 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 CCU99145.1 - 8e-27 93.1 6.2 3.2e-08 33.8 0.0 5.8 2 2 4 6 6 6 6 Ankyrin repeats (many copies) SPX PF03105.14 CCU99145.1 - 9.3e-21 74.8 5.3 3.2e-11 43.5 1.3 2.3 1 1 1 2 2 2 2 SPX domain Ank_5 PF13857.1 CCU99145.1 - 1.1e-20 73.2 13.3 1e-05 25.5 0.1 7.4 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCU99145.1 - 1.3e-19 68.2 9.7 0.0034 17.4 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat GDPD PF03009.12 CCU99145.1 - 3.4e-11 43.1 0.0 8.7e-11 41.8 0.0 1.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF2423 PF10338.4 CCU99146.1 - 1.5e-13 50.5 5.3 1.5e-13 50.5 3.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) FANCI_HD2 PF14680.1 CCU99146.1 - 0.036 13.1 0.2 0.043 12.9 0.1 1.1 1 0 0 1 1 1 0 FANCI helical domain 2 Peptidase_M16 PF00675.15 CCU99146.1 - 0.089 12.5 0.2 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) MDFI PF15316.1 CCU99146.1 - 2.8 7.9 4.1 1.7 8.6 1.6 1.6 1 1 0 1 1 1 0 MyoD family inhibitor Pkinase PF00069.20 CCU99147.1 - 1.6e-70 237.2 0.0 1.9e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99147.1 - 1.4e-37 129.1 0.0 1.7e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU99147.1 - 3.8e-07 29.3 0.0 6.1e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCU99147.1 - 0.00013 21.1 0.3 0.00024 20.2 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CCU99147.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CCU99147.1 - 0.014 15.1 0.1 0.039 13.6 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Cpn60_TCP1 PF00118.19 CCU99148.1 - 5.2e-137 457.4 9.0 5.9e-137 457.2 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 CCU99148.1 - 7.1e-05 22.1 0.2 0.0023 17.1 0.0 2.4 2 0 0 2 2 2 2 Telomere recombination Brix PF04427.13 CCU99149.1 - 5.5e-55 186.0 0.0 1.3e-54 184.7 0.0 1.6 2 0 0 2 2 2 1 Brix domain ATP-synt_E PF05680.7 CCU99149.1 - 0.44 10.5 5.6 1.1 9.2 3.9 1.7 1 0 0 1 1 1 0 ATP synthase E chain Mad3_BUB1_I PF08311.7 CCU99150.1 - 2.4e-35 121.0 0.0 3.7e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 CCU99150.1 - 2.2e-14 53.2 0.0 3.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99150.1 - 0.021 13.8 0.0 0.056 12.5 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase AFG1_ATPase PF03969.11 CCU99151.1 - 3.3e-86 289.3 0.0 5.8e-81 272.0 0.0 3.1 3 0 0 3 3 3 3 AFG1-like ATPase AAA_22 PF13401.1 CCU99151.1 - 5.1e-06 26.6 0.0 4e-05 23.7 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CCU99151.1 - 9.9e-05 22.3 0.1 0.00097 19.1 0.0 2.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 CCU99151.1 - 0.012 15.0 0.1 0.052 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CCU99151.1 - 0.028 14.5 0.0 0.15 12.2 0.0 2.2 2 1 1 3 3 3 0 RNA helicase Vma12 PF11712.3 CCU99152.1 - 7e-14 51.7 0.0 9.3e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase cobW PF02492.14 CCU99153.1 - 2.1e-34 118.5 0.1 3.8e-34 117.6 0.0 1.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CCU99153.1 - 0.0067 15.2 0.5 0.012 14.4 0.3 1.5 1 1 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 CCU99153.1 - 0.095 13.0 0.0 0.17 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain zf-Mss51 PF13824.1 CCU99154.1 - 1.7e-21 75.8 1.2 2.9e-21 75.0 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 cwf18 PF08315.7 CCU99155.1 - 1e-18 68.0 0.3 1.2e-18 67.7 0.2 1.0 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor PI3_PI4_kinase PF00454.22 CCU99156.1 - 3.8e-33 114.9 0.0 5.6e-32 111.0 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CCU99156.1 - 3.2e-12 46.0 0.0 5.8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ribosomal_S9 PF00380.14 CCU99157.1 - 1.3e-19 70.5 0.1 3e-19 69.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_S11 PF00411.14 CCU99158.1 - 2.5e-13 50.1 0.1 3.7e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 DPM3 PF08285.6 CCU99159.1 - 1.4e-26 92.1 0.1 1.5e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4229 PF14012.1 CCU99159.1 - 2.8 7.9 9.2 0.95 9.4 4.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4229) Hat1_N PF10394.4 CCU99160.1 - 1.1e-34 119.8 0.0 1.6e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.19 CCU99160.1 - 0.013 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MOZ_SAS PF01853.13 CCU99160.1 - 0.021 14.0 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_10 PF13673.1 CCU99160.1 - 0.071 13.2 0.0 0.45 10.6 0.0 2.2 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCU99160.1 - 0.099 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TIP41 PF04176.8 CCU99161.1 - 1.8e-41 141.4 0.0 1.3e-38 132.0 0.0 2.3 2 0 0 2 2 2 2 TIP41-like family DLH PF01738.13 CCU99162.1 - 1.5e-13 50.5 0.0 1.7e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCU99162.1 - 0.00024 20.9 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CCU99164.1 - 5.2e-09 35.6 0.0 6.4e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCU99164.1 - 0.0036 17.0 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family RasGEF PF00617.14 CCU99165.1 - 2e-55 187.4 0.1 2.9e-55 186.9 0.1 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CCU99165.1 - 1.5e-22 79.6 0.4 5.6e-22 77.8 0.1 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Branch PF02485.16 CCU99165.1 - 0.087 11.9 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Core-2/I-Branching enzyme WD40 PF00400.27 CCU99166.1 - 1.1e-16 59.9 13.2 1.3e-06 28.0 0.1 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat MCM PF00493.18 CCU99167.1 - 2.3e-141 470.3 0.2 3e-141 469.9 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCU99167.1 - 2.8e-17 63.3 0.0 6.6e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCU99167.1 - 2.5e-06 26.7 0.0 0.00037 19.7 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCU99167.1 - 1.5e-05 24.7 0.0 3.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCU99167.1 - 0.0016 18.0 0.1 0.0089 15.6 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 CCU99167.1 - 0.038 14.3 0.3 0.16 12.3 0.2 2.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCU99167.1 - 0.041 13.3 0.0 0.9 8.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Band_7 PF01145.20 CCU99168.1 - 7.6e-19 68.2 0.1 1.3e-18 67.5 0.1 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family RA PF00788.18 CCU99169.1 - 4.1e-18 65.6 0.8 5.8e-14 52.3 0.0 3.8 4 0 0 4 4 4 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 CCU99169.1 - 0.034 13.5 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 SH3 domain TUG-UBL1 PF11470.3 CCU99169.1 - 0.18 11.7 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 GLUT4 regulating protein TUG Chitin_synth_2 PF03142.10 CCU99170.1 - 1.3e-270 898.3 0.2 2.2e-270 897.5 0.2 1.4 1 1 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 CCU99170.1 - 2.8e-15 56.7 0.1 5.7e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CCU99170.1 - 1.8e-13 50.6 7.5 1.8e-13 50.6 5.2 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 CCU99170.1 - 2.4e-06 26.9 0.0 5e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CCU99170.1 - 0.0033 17.1 0.0 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Syndecan PF01034.15 CCU99170.1 - 0.12 12.0 0.1 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 Syndecan domain RRM_1 PF00076.17 CCU99171.1 - 5.5e-16 57.9 0.2 1.2e-15 56.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99171.1 - 1.5e-12 47.3 0.0 2.4e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99171.1 - 6e-10 38.8 0.3 2.3e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCU99171.1 - 0.062 13.1 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Phage_glycop_gL PF11108.3 CCU99171.1 - 0.083 12.8 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Viral glycoprotein L FIST PF08495.5 CCU99172.1 - 0.00084 18.5 0.0 0.0029 16.7 0.0 1.8 1 1 0 1 1 1 1 FIST N domain PrpF PF04303.8 CCU99173.1 - 1.6e-52 178.4 1.9 6.2e-36 123.9 0.3 2.6 2 1 0 2 2 2 2 PrpF protein Epimerase PF01370.16 CCU99174.1 - 1.6e-42 145.5 0.0 1.9e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CCU99174.1 - 5.5e-28 96.7 0.0 1.2e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit RmlD_sub_bind PF04321.12 CCU99174.1 - 1.8e-11 43.4 0.0 5.7e-11 41.8 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CCU99174.1 - 6.4e-11 41.4 0.0 1.5e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CCU99174.1 - 2.4e-08 34.0 0.1 6.6e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 CCU99174.1 - 3e-08 32.8 0.0 6.1e-08 31.8 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 CCU99174.1 - 1.5e-07 31.2 0.1 6.2e-07 29.2 0.0 2.1 2 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 CCU99174.1 - 2.6e-07 29.8 0.0 1.5e-06 27.3 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CCU99174.1 - 5.4e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 CCU99174.1 - 0.039 13.6 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RPA_interact_C PF14768.1 CCU99176.1 - 0.0021 18.3 0.0 0.0033 17.7 0.0 1.3 1 0 0 1 1 1 1 Replication protein A interacting C-terminal Ribosomal_L11 PF00298.14 CCU99177.1 - 9.2e-12 44.9 0.1 1.5e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 CCU99177.1 - 4.2e-05 22.9 0.0 8.5e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain WD40 PF00400.27 CCU99178.1 - 3.7e-64 210.4 20.8 4.7e-13 48.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CCU99178.1 - 0.0001 20.6 5.2 0.025 12.7 0.7 3.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CCU99178.1 - 0.009 14.3 0.0 0.6 8.3 0.1 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 CCU99178.1 - 0.044 13.4 0.6 40 4.0 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 CCU99178.1 - 0.068 11.8 1.1 2.4 6.8 0.1 2.9 2 1 1 3 3 3 0 Nup133 N terminal like DUF1416 PF07210.7 CCU99178.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) RRM_1 PF00076.17 CCU99179.1 - 3.4e-23 81.0 0.0 4.4e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99179.1 - 1.9e-19 69.3 0.0 2.5e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99179.1 - 1.7e-11 43.8 0.0 2.3e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyoxal_oxid_N PF07250.6 CCU99180.1 - 2.7e-29 101.9 0.0 3.9e-26 91.6 0.0 3.7 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CCU99180.1 - 1.2e-19 70.1 0.1 2.7e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Podoplanin PF05808.6 CCU99180.1 - 0.00086 18.8 0.0 0.0022 17.5 0.0 1.6 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.5 CCU99180.1 - 0.0029 16.8 2.3 0.0067 15.7 1.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2668 PF10873.3 CCU99180.1 - 0.02 15.0 0.2 0.065 13.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Amnionless PF14828.1 CCU99180.1 - 0.032 12.7 0.0 0.048 12.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless Kelch_4 PF13418.1 CCU99180.1 - 0.23 11.2 9.7 0.82 9.4 0.2 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain MtrF PF09472.5 CCU99180.1 - 2.9 7.1 4.6 6 6.1 3.2 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Sec23_trunk PF04811.10 CCU99181.1 - 8.5e-59 198.8 0.0 1.3e-58 198.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Mito_carr PF00153.22 CCU99181.1 - 1.1e-52 175.6 1.8 1.2e-22 79.3 0.0 4.6 4 1 1 5 5 5 3 Mitochondrial carrier protein Sec23_helical PF04815.10 CCU99181.1 - 1e-26 92.3 0.1 1.8e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCU99181.1 - 6e-17 61.9 0.0 1.5e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCU99181.1 - 1.7e-15 56.2 5.6 3.8e-15 55.1 3.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCU99181.1 - 0.0024 17.5 0.0 0.0064 16.1 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Thymidylat_synt PF00303.14 CCU99182.1 - 3.8e-106 354.0 0.0 4.9e-106 353.6 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.17 CCU99182.1 - 2.4e-23 82.9 0.0 4.7e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4131 PF13567.1 CCU99183.1 - 7.2 5.9 6.5 16 4.8 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) zf-MYND PF01753.13 CCU99184.1 - 2.4e-07 30.5 15.1 5e-07 29.4 10.5 1.6 1 0 0 1 1 1 1 MYND finger Mur_ligase_M PF08245.7 CCU99185.1 - 0.0078 16.2 0.0 0.037 14.0 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain tRNA_anti-codon PF01336.20 CCU99187.1 - 5.6e-11 42.1 0.2 1.2e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain BOF PF04076.8 CCU99187.1 - 0.2 11.5 3.5 0.17 11.7 0.8 2.1 1 1 1 2 2 2 0 Bacterial OB fold (BOF) protein AAA PF00004.24 CCU99189.1 - 1.5e-40 138.4 0.0 2.4e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCU99189.1 - 6e-07 29.6 0.2 0.0026 17.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 CCU99189.1 - 2.4e-05 24.3 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CCU99189.1 - 6e-05 22.1 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 CCU99189.1 - 6.6e-05 22.6 0.2 0.00054 19.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCU99189.1 - 0.00021 21.3 0.2 0.0014 18.6 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 CCU99189.1 - 0.00027 20.9 0.4 0.049 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCU99189.1 - 0.0018 17.3 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCU99189.1 - 0.0024 17.7 0.0 0.0066 16.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCU99189.1 - 0.0052 17.5 1.2 0.016 16.0 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCU99189.1 - 0.0057 16.3 0.2 0.013 15.2 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CCU99189.1 - 0.0058 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CCU99189.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CCU99189.1 - 0.0085 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein KaiC PF06745.8 CCU99189.1 - 0.011 14.8 0.1 0.2 10.7 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.1 CCU99189.1 - 0.012 14.9 0.6 0.7 9.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 CCU99189.1 - 0.013 15.8 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CCU99189.1 - 0.022 13.6 0.0 0.058 12.2 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 CCU99189.1 - 0.043 12.9 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 CCU99189.1 - 0.067 11.9 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus DUF2075 PF09848.4 CCU99189.1 - 0.075 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 CCU99189.1 - 0.077 13.1 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CCU99189.1 - 0.099 12.3 0.2 0.42 10.2 0.1 1.9 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.11 CCU99189.1 - 0.1 11.8 0.1 0.38 9.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 CCU99189.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Tim17 PF02466.14 CCU99190.1 - 5.6e-29 100.7 10.9 1.1e-27 96.6 7.6 2.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Mito_fiss_reg PF05308.6 CCU99190.1 - 0.073 12.4 1.0 0.097 12.0 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator E1-E2_ATPase PF00122.15 CCU99191.1 - 3.4e-66 222.5 1.4 3.4e-66 222.5 0.9 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CCU99191.1 - 2e-24 87.2 0.1 4.5e-24 86.0 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCU99191.1 - 2.4e-13 50.6 0.0 4.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCU99191.1 - 3.3e-09 36.0 0.0 7.6e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCU99191.1 - 0.00099 18.7 0.1 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCU99191.1 - 0.0033 17.3 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Abhydrolase_5 PF12695.2 CCU99192.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 CCU99192.1 - 0.024 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Cpn60_TCP1 PF00118.19 CCU99193.1 - 6.6e-157 523.0 0.9 7.5e-157 522.8 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1572 PF07609.6 CCU99193.1 - 0.055 13.0 0.0 0.86 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) SNF2_N PF00176.18 CCU99195.1 - 3.6e-68 229.5 0.0 4.9e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCU99195.1 - 4.1e-12 45.7 0.0 7.1e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 CCU99195.1 - 3.3e-08 33.0 3.0 3.3e-08 33.0 2.1 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCU99195.1 - 9.6e-08 31.9 3.8 9.6e-08 31.9 2.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 CCU99195.1 - 1e-07 31.9 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 CCU99195.1 - 9.4e-07 28.5 6.0 9.4e-07 28.5 4.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCU99195.1 - 1.6e-06 27.6 4.4 1.6e-06 27.6 3.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 CCU99195.1 - 1e-05 25.1 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 CCU99195.1 - 0.00015 21.4 3.7 0.00015 21.4 2.5 2.2 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCU99195.1 - 0.0072 16.1 2.2 0.0072 16.1 1.6 2.7 2 2 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCU99195.1 - 0.016 14.8 0.6 0.016 14.8 0.4 2.3 2 0 0 2 2 2 0 RING-type zinc-finger AAA_22 PF13401.1 CCU99195.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain zf-Nse PF11789.3 CCU99195.1 - 0.12 11.8 1.9 0.3 10.6 1.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit HTH_20 PF12840.2 CCU99196.1 - 0.0078 15.9 0.0 0.88 9.4 0.0 3.8 3 1 0 3 3 3 1 Helix-turn-helix domain WD40 PF00400.27 CCU99197.1 - 1e-39 133.0 7.5 1.7e-08 33.9 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCU99197.1 - 5e-31 106.4 0.3 1.3e-30 105.1 0.1 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 CCU99197.1 - 0.039 12.0 0.9 3.1 5.8 0.2 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCU99197.1 - 0.047 12.4 0.0 0.64 8.6 0.0 2.1 1 1 0 1 1 1 0 Nup133 N terminal like Apc4_WD40 PF12894.2 CCU99197.1 - 0.076 12.5 0.0 1 8.9 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.24 CCU99198.1 - 6.2e-41 139.7 0.1 1.1e-40 138.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU99198.1 - 1.2e-23 82.7 0.1 2.1e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CCU99198.1 - 0.0076 15.3 0.1 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Ala_racemase_N PF01168.15 CCU99198.1 - 0.056 12.9 0.0 0.81 9.2 0.0 2.1 2 0 0 2 2 2 0 Alanine racemase, N-terminal domain Pam17 PF08566.5 CCU99199.1 - 4.4e-57 192.5 0.0 5.3e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DnaJ PF00226.26 CCU99200.1 - 8.6e-16 57.4 0.4 1.6e-15 56.5 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain RrnaAD PF00398.15 CCU99201.1 - 3.2e-20 72.2 0.0 5e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PBP PF01161.15 CCU99202.1 - 1.1e-21 77.2 0.1 1.7e-21 76.6 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ATG11 PF10377.4 CCU99203.1 - 8.4e-19 67.7 0.0 1.7e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 11 Baculo_PEP_C PF04513.7 CCU99203.1 - 0.0056 16.5 4.4 0.07 12.9 0.0 3.8 4 1 0 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus Mnd1 PF03962.10 CCU99203.1 - 0.0074 15.9 0.1 0.08 12.5 0.1 2.4 2 0 0 2 2 2 1 Mnd1 family HR1 PF02185.11 CCU99203.1 - 0.049 13.3 0.0 19 5.0 0.0 2.8 2 0 0 2 2 2 0 Hr1 repeat DUF684 PF05075.9 CCU99203.1 - 0.051 12.1 0.0 0.1 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF684) Tektin PF03148.9 CCU99203.1 - 0.07 11.6 5.2 0.43 9.0 0.0 2.9 4 0 0 4 4 4 0 Tektin family CENP-F_N PF10481.4 CCU99203.1 - 0.13 11.6 1.5 0.6 9.4 0.0 2.6 3 1 0 3 3 3 0 Cenp-F N-terminal domain DUF3584 PF12128.3 CCU99203.1 - 0.31 8.2 6.5 0.36 8.1 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF3138 PF11336.3 CCU99203.1 - 0.39 8.8 0.5 0.6 8.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) APG17 PF04108.7 CCU99203.1 - 4 6.1 9.7 7 5.3 0.2 3.3 3 1 0 3 3 3 0 Autophagy protein Apg17 Reo_sigmaC PF04582.7 CCU99203.1 - 6 5.9 12.1 0.19 10.8 0.2 3.1 4 0 0 4 4 4 0 Reovirus sigma C capsid protein Fip1 PF05182.8 CCU99204.1 - 3.3e-22 77.4 1.0 6e-22 76.6 0.7 1.4 1 0 0 1 1 1 1 Fip1 motif MPC PF03650.8 CCU99205.1 - 9.6e-29 99.7 0.4 1.1e-28 99.6 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) VirionAssem_T7 PF11653.3 CCU99206.1 - 0.015 16.0 4.2 0.043 14.5 2.9 1.8 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein Glyoxalase PF00903.20 CCU99206.1 - 5.1 7.0 9.6 1.7 8.6 4.5 2.0 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RNase_P_p30 PF01876.11 CCU99207.1 - 5.8e-32 110.0 0.0 8.8e-32 109.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Peptidase_M50B PF13398.1 CCU99208.1 - 6.4e-35 120.3 5.3 8e-35 120.0 3.7 1.0 1 0 0 1 1 1 1 Peptidase M50B-like BioY PF02632.9 CCU99208.1 - 0.18 11.4 3.4 0.29 10.7 0.6 2.0 2 0 0 2 2 2 0 BioY family DUF4131 PF13567.1 CCU99208.1 - 9.7 5.5 7.1 1.8 7.9 2.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Rad51 PF08423.6 CCU99210.1 - 1.1e-66 224.3 3.8 3.6e-59 199.7 0.2 2.2 1 1 1 2 2 2 2 Rad51 HHH_5 PF14520.1 CCU99210.1 - 7.7e-07 29.1 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_25 PF13481.1 CCU99210.1 - 0.001 18.5 0.1 0.0019 17.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.10 CCU99210.1 - 0.056 12.3 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Rad1 PF02144.11 CCU99211.1 - 4.1e-59 199.5 0.0 4.7e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 WD40 PF00400.27 CCU99212.1 - 5.3e-21 73.6 5.0 6.5e-11 41.6 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCU99212.1 - 0.15 10.7 0.0 3.4 6.3 0.0 2.4 1 1 0 2 2 2 0 Nup133 N terminal like Chitin_synth_2 PF03142.10 CCU99213.1 - 2e-229 762.3 0.0 2.7e-229 761.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CCU99213.1 - 1.4e-94 317.5 0.0 1.8e-94 317.1 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.1 CCU99213.1 - 2.1e-19 70.2 2.2 3.4e-15 56.4 0.0 3.3 4 0 0 4 4 4 2 Glycosyltransferase like family 2 DEK_C PF08766.6 CCU99213.1 - 1.4e-14 53.5 0.0 9.9e-14 50.8 0.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 CCU99213.1 - 1.6e-14 54.1 3.0 1.6e-14 54.1 2.1 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 CCU99213.1 - 1.2e-12 47.4 0.0 1.1e-08 34.8 0.0 2.5 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 CCU99213.1 - 3.6e-06 26.7 0.0 0.00059 19.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CCU99213.1 - 7e-06 25.4 0.1 0.00045 19.5 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 HTH_16 PF12645.2 CCU99213.1 - 0.079 12.9 0.2 20 5.1 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Pkinase PF00069.20 CCU99214.1 - 8.6e-67 225.0 0.0 1e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99214.1 - 2.1e-28 99.1 0.0 2.9e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCU99214.1 - 0.00014 21.0 0.0 0.00026 20.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCU99214.1 - 0.0004 19.8 0.1 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CCU99214.1 - 0.0021 17.8 0.4 0.066 12.9 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCU99214.1 - 0.0065 15.4 0.0 0.02 13.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like YukC PF10140.4 CCU99214.1 - 0.027 13.0 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Seadorna_VP7 PF07387.6 CCU99214.1 - 0.15 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Sel1 PF08238.7 CCU99215.1 - 2.4e-10 40.7 18.1 6.7e-08 32.9 0.1 6.2 6 0 0 6 6 6 2 Sel1 repeat TPR_2 PF07719.12 CCU99215.1 - 0.029 14.2 5.5 0.13 12.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CCDC144C PF14915.1 CCU99215.1 - 0.091 11.6 0.8 0.13 11.1 0.5 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region TPR_8 PF13181.1 CCU99215.1 - 0.12 12.2 0.0 0.88 9.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat eIF-5a PF01287.15 CCU99216.1 - 2.5e-27 94.6 0.2 3.4e-27 94.1 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CCU99216.1 - 0.00013 21.5 0.5 0.00023 20.7 0.4 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 CCU99216.1 - 0.09 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain HLH PF00010.21 CCU99217.1 - 1.7e-13 50.0 0.1 3e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NAD_binding_7 PF13241.1 CCU99218.1 - 2.4e-27 95.1 0.0 3.4e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 CCU99218.1 - 5e-14 50.9 0.3 9.7e-14 50.0 0.2 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.1 CCU99218.1 - 2.1e-11 42.9 0.0 3.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Telomere_reg-2 PF10193.4 CCU99219.1 - 1.2e-23 83.5 0.0 2.3e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Telomere length regulation protein Pil1 PF13805.1 CCU99220.1 - 9.5e-18 64.3 1.7 1.6e-17 63.5 1.2 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2730 PF10805.3 CCU99220.1 - 0.0084 15.8 1.0 0.018 14.7 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Gp-FAR-1 PF05823.7 CCU99220.1 - 0.055 13.4 0.3 0.099 12.5 0.2 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) GAS PF13851.1 CCU99220.1 - 0.076 12.1 2.7 0.15 11.2 1.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 CCU99220.1 - 0.59 9.8 5.1 0.36 10.5 1.5 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Ribonuc_P_40 PF08584.6 CCU99221.1 - 1.6e-40 138.9 0.0 2.4e-37 128.5 0.0 2.3 2 1 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit NIPSNAP PF07978.8 CCU99222.1 - 3.5e-07 30.1 1.9 0.0033 17.3 0.1 2.3 2 1 0 2 2 2 2 NIPSNAP Katanin_con80 PF13925.1 CCU99222.1 - 0.03 14.0 0.1 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 con80 domain of Katanin TEA PF01285.13 CCU99223.1 - 4.2e-33 115.1 0.0 8.3e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain family DUF59 PF01883.14 CCU99224.1 - 1.4e-10 40.9 0.1 3.1e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 Sec1 PF00995.18 CCU99225.1 - 1e-110 371.0 0.0 1.2e-110 370.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3182 PF11379.3 CCU99225.1 - 0.012 14.3 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) tRNA-synt_1e PF01406.14 CCU99226.1 - 1.5e-122 408.4 0.0 2.1e-122 407.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CCU99226.1 - 2.7e-09 36.1 0.5 8.1e-05 21.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 CCU99226.1 - 6.7e-06 26.2 0.8 7.4e-05 22.9 0.0 2.8 2 0 0 2 2 2 1 DALR domain tRNA-synt_1 PF00133.17 CCU99226.1 - 7.1e-05 21.0 0.0 0.0068 14.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.16 CCU99226.1 - 7.5e-05 21.5 0.1 0.0036 15.9 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain DUF1887 PF09002.6 CCU99226.1 - 0.012 14.0 0.2 0.022 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) tRNA-synt_1f PF01921.13 CCU99226.1 - 0.058 12.0 0.1 7.5 5.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) EGL-1 PF11430.3 CCU99226.1 - 0.67 9.6 2.6 1.6 8.4 1.8 1.5 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 Methyltransf_16 PF10294.4 CCU99227.1 - 2e-44 151.1 0.0 2.4e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCU99227.1 - 0.00056 20.4 0.0 0.00079 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCU99227.1 - 0.066 12.8 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CCU99227.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Exo_endo_phos PF03372.18 CCU99228.1 - 1.4e-22 80.9 0.0 2.1e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LUC7 PF03194.10 CCU99229.1 - 9e-74 248.2 3.9 1.1e-73 247.9 2.7 1.0 1 0 0 1 1 1 1 LUC7 N_terminus APG6 PF04111.7 CCU99229.1 - 0.0049 15.9 1.5 0.007 15.4 1.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 BLOC1_2 PF10046.4 CCU99229.1 - 0.029 14.4 2.6 0.15 12.2 0.5 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ly49 PF08391.5 CCU99229.1 - 0.033 14.3 6.1 0.59 10.2 2.1 2.1 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Syntaxin_2 PF14523.1 CCU99229.1 - 0.044 13.7 2.8 0.52 10.3 1.2 2.2 2 0 0 2 2 2 0 Syntaxin-like protein FdhE PF04216.7 CCU99229.1 - 0.1 12.2 0.8 0.33 10.6 0.1 2.0 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation Oxysterol_BP PF01237.13 CCU99229.1 - 0.13 10.7 1.0 0.15 10.4 0.7 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein AAA_13 PF13166.1 CCU99229.1 - 0.14 10.6 4.4 0.55 8.6 3.1 1.7 1 1 0 1 1 1 0 AAA domain DUF342 PF03961.8 CCU99229.1 - 0.16 10.3 4.6 0.1 11.0 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF2357 PF09823.4 CCU99229.1 - 0.22 10.5 2.7 0.15 11.1 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) V_ATPase_I PF01496.14 CCU99229.1 - 0.27 9.0 3.3 0.32 8.8 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 CCU99229.1 - 0.53 9.9 9.5 0.24 11.0 4.5 1.7 1 1 1 2 2 2 0 Mnd1 family UPF0193 PF05250.6 CCU99229.1 - 2.3 7.7 9.6 2.2 7.8 5.5 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0193) IncA PF04156.9 CCU99229.1 - 8.4 5.9 11.3 19 4.7 7.8 1.6 1 1 0 1 1 1 0 IncA protein Thymidylate_kin PF02223.12 CCU99230.1 - 1.3e-40 138.8 0.0 1.9e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 CCU99230.1 - 0.025 14.4 0.0 0.069 13.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain Abhydro_lipase PF04083.11 CCU99230.1 - 0.033 13.5 0.1 10 5.5 0.0 2.7 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region AAA_28 PF13521.1 CCU99230.1 - 0.05 13.5 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 CCU99230.1 - 0.072 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CENP_C_N PF15622.1 CCU99230.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal CSTF2_hinge PF14327.1 CCU99231.1 - 3e-28 97.7 0.5 3e-28 97.7 0.4 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 CCU99231.1 - 4.7e-10 38.5 7.8 4.7e-10 38.5 5.4 2.1 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.17 CCU99231.1 - 0.00081 18.9 0.2 0.0016 18.0 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prefoldin_2 PF01920.15 CCU99232.1 - 2.6e-13 49.6 2.2 3.1e-13 49.4 1.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF2524 PF10732.4 CCU99232.1 - 0.01 15.9 0.1 0.01 15.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Uds1 PF15456.1 CCU99232.1 - 0.094 12.7 1.7 0.12 12.3 1.2 1.1 1 0 0 1 1 1 0 Up-regulated During Septation B56 PF01603.15 CCU99233.1 - 3.8e-160 533.0 6.6 4.9e-160 532.6 4.6 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec66 PF09802.4 CCU99234.1 - 1.1e-31 109.7 0.2 1.3e-31 109.5 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Glyco_tranf_2_3 PF13641.1 CCU99234.1 - 0.05 13.4 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Transket_pyr PF02779.19 CCU99236.1 - 5.8e-41 139.9 0.1 5.7e-40 136.7 0.1 2.1 1 1 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCU99236.1 - 3.6e-38 130.3 0.0 7.1e-38 129.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Pyrophosphatase PF00719.14 CCU99237.1 - 5.3e-53 178.6 0.2 7e-53 178.2 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase peroxidase PF00141.18 CCU99238.1 - 2.4e-47 161.3 0.0 3.5e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4003 PF13170.1 CCU99238.1 - 0.085 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Arrestin_C PF02752.17 CCU99239.1 - 1.8e-05 24.8 0.0 9.3e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCU99239.1 - 0.14 11.9 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain E1-E2_ATPase PF00122.15 CCU99241.1 - 5.1e-67 225.2 2.7 5.1e-67 225.2 1.9 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCU99241.1 - 4.4e-48 163.2 6.5 1.3e-47 161.6 2.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCU99241.1 - 4.3e-31 108.9 0.0 1.4e-30 107.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCU99241.1 - 1.6e-19 69.6 0.0 3.1e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CCU99241.1 - 1.5e-17 62.7 0.0 4.1e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CCU99241.1 - 6.9e-17 62.2 0.5 2.4e-16 60.4 0.1 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCU99241.1 - 3.1e-09 36.7 0.8 7.8e-07 28.9 0.9 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DeoRC PF00455.17 CCU99241.1 - 0.004 16.8 0.2 0.012 15.2 0.2 1.8 1 0 0 1 1 1 1 DeoR C terminal sensor domain Proteasome_A_N PF10584.4 CCU99241.1 - 0.012 14.9 0.2 0.025 13.9 0.1 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature HAD_2 PF13419.1 CCU99241.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase L31 PF09784.4 CCU99242.1 - 1.1e-37 128.1 0.3 1.3e-37 128.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 F_bP_aldolase PF01116.15 CCU99243.1 - 3.8e-100 334.6 0.0 4.3e-100 334.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Vac_ImportDeg PF09783.4 CCU99244.1 - 5.3e-22 78.1 0.7 2.6e-14 53.0 0.1 3.1 2 1 1 3 3 3 3 Vacuolar import and degradation protein Fasciclin PF02469.17 CCU99245.1 - 6.2e-55 184.6 0.0 4.7e-14 52.4 0.0 5.7 5 2 0 5 5 5 5 Fasciclin domain Radical_SAM PF04055.16 CCU99246.1 - 7.8e-16 58.6 0.2 2.7e-15 56.9 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CCU99246.1 - 5.3e-11 42.4 0.0 1.6e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCU99246.1 - 0.0082 16.2 0.0 0.03 14.4 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCU99246.1 - 0.091 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Myotub-related PF06602.9 CCU99247.1 - 2e-116 388.6 0.0 3.1e-116 388.0 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 CCU99247.1 - 0.00078 18.8 0.1 0.0023 17.3 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 CCU99247.1 - 0.0022 17.5 0.0 0.0044 16.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCU99247.1 - 0.0047 17.2 0.0 0.0098 16.1 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family LRR_6 PF13516.1 CCU99248.1 - 1.5e-12 46.1 0.7 2.9 8.2 0.0 8.1 8 1 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.2 CCU99248.1 - 1.5e-06 27.6 10.9 0.34 10.5 0.2 5.9 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCU99248.1 - 8e-05 22.3 12.1 0.05 13.3 0.1 5.2 5 2 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 CCU99248.1 - 0.0004 20.0 9.2 16 6.0 1.5 7.3 6 2 0 6 6 6 1 Leucine Rich Repeat RXT2_N PF08595.6 CCU99248.1 - 0.77 9.5 3.6 1.3 8.8 2.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal LRR_7 PF13504.1 CCU99248.1 - 2.1 8.8 13.8 4.2 7.9 0.2 6.1 7 0 0 7 7 7 0 Leucine rich repeat Nucleoplasmin PF03066.10 CCU99248.1 - 6.2 6.3 11.5 10 5.6 8.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 CCU99248.1 - 6.5 6.3 10.8 12 5.4 7.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Lactamase_B_2 PF12706.2 CCU99249.1 - 2.2e-14 53.4 0.0 3.8e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CCU99249.1 - 8.4e-11 41.8 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily adh_short PF00106.20 CCU99249.1 - 1.5e-05 24.9 0.2 7.5e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase WD40 PF00400.27 CCU99250.1 - 9.2e-24 82.4 4.9 5.5e-08 32.3 0.1 6.3 6 1 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 CCU99250.1 - 9.2e-07 28.5 0.7 9.1e-06 25.3 0.1 2.2 1 1 1 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 CCU99250.1 - 1.3e-05 25.2 2.4 0.24 11.7 0.0 4.1 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 CCU99250.1 - 0.00011 21.5 1.9 0.41 10.2 0.0 3.7 3 0 0 3 3 3 2 PQQ enzyme repeat FMO-like PF00743.14 CCU99251.1 - 1.5e-11 43.2 0.0 9.6e-08 30.6 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CCU99251.1 - 0.0042 16.0 0.0 0.034 13.0 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 CCU99251.1 - 0.055 13.5 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 CCU99252.1 - 4.4e-34 117.8 0.0 5.6e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99252.1 - 8.2e-12 44.7 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase zf-Tim10_DDP PF02953.10 CCU99253.1 - 1.3e-18 66.0 0.3 1.6e-18 65.7 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DNA_pol_phi PF04931.8 CCU99254.1 - 8e-71 238.8 0.0 2e-70 237.5 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase phi TFIIA PF03153.8 CCU99254.1 - 0.24 11.2 14.1 0.53 10.1 9.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rhodanese PF00581.15 CCU99255.1 - 1.7e-11 44.4 0.0 3.5e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain PUF PF00806.14 CCU99257.1 - 2.2e-19 67.7 0.0 0.0018 17.6 0.0 4.7 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat DUF3400 PF11880.3 CCU99257.1 - 0.0051 16.0 0.0 0.035 13.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3400) DUF3763 PF12592.3 CCU99259.1 - 0.0029 17.2 0.3 0.2 11.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3763) Lzipper-MIP1 PF14389.1 CCU99259.1 - 0.062 13.4 0.9 0.16 12.0 0.6 1.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Spc24 PF08286.6 CCU99261.1 - 4.9e-05 22.9 1.6 4.9e-05 22.9 1.1 2.3 2 1 0 2 2 2 1 Spc24 subunit of Ndc80 GAS PF13851.1 CCU99261.1 - 0.0061 15.7 10.8 0.0077 15.4 7.5 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding F_actin_bind PF08919.5 CCU99261.1 - 0.015 15.0 2.1 0.045 13.4 1.5 1.8 1 1 0 1 1 1 0 F-actin binding HCMV_UL139 PF12507.3 CCU99261.1 - 0.025 14.7 0.1 0.043 13.9 0.0 1.4 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein IncA PF04156.9 CCU99261.1 - 0.052 13.1 13.5 0.14 11.7 3.7 2.2 1 1 1 2 2 2 0 IncA protein MCPsignal PF00015.16 CCU99261.1 - 0.056 12.9 2.9 0.084 12.3 2.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.4 CCU99261.1 - 0.1 12.7 5.6 0.42 10.7 0.7 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med9 PF07544.8 CCU99261.1 - 0.18 11.5 9.7 0.16 11.7 0.8 2.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PilJ PF13675.1 CCU99261.1 - 0.18 12.1 2.1 2 8.7 0.1 2.2 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF342 PF03961.8 CCU99261.1 - 0.22 9.9 3.7 0.25 9.7 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Laminin_II PF06009.7 CCU99261.1 - 0.24 11.1 5.2 0.36 10.5 3.6 1.2 1 0 0 1 1 1 0 Laminin Domain II UPF0122 PF04297.9 CCU99261.1 - 0.25 11.3 3.3 5.1 7.1 2.3 2.4 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Fib_alpha PF08702.5 CCU99261.1 - 0.38 10.8 6.6 0.75 9.9 4.6 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 CCU99261.1 - 0.39 9.7 9.1 0.55 9.2 6.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Sin3_corepress PF08295.7 CCU99261.1 - 0.51 10.1 4.5 0.45 10.2 1.4 2.0 1 1 0 2 2 2 0 Sin3 family co-repressor Mnd1 PF03962.10 CCU99261.1 - 0.61 9.7 8.3 0.18 11.4 3.5 1.6 1 1 1 2 2 2 0 Mnd1 family Atg14 PF10186.4 CCU99261.1 - 0.68 8.8 6.1 0.86 8.4 4.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 CCU99261.1 - 0.85 9.4 10.7 9.2 6.1 0.9 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1515 PF07439.6 CCU99261.1 - 1.2 8.9 5.8 0.99 9.2 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DUF904 PF06005.7 CCU99261.1 - 1.5 9.1 12.2 8.9 6.6 1.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF904) Spc7 PF08317.6 CCU99261.1 - 1.8 7.1 11.6 5 5.6 8.0 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 CCU99261.1 - 2 7.9 11.7 0.72 9.3 4.5 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF848 PF05852.6 CCU99261.1 - 2.2 8.1 10.1 3 7.6 7.0 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DivIC PF04977.10 CCU99261.1 - 2.3 7.7 8.0 1.4 8.4 1.4 2.6 1 1 1 2 2 2 0 Septum formation initiator Mst1_SARAH PF11629.3 CCU99261.1 - 2.4 8.0 5.9 8.1 6.3 1.1 2.7 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 Sec20 PF03908.8 CCU99261.1 - 2.4 7.8 5.7 13 5.6 0.1 2.5 1 1 1 2 2 2 0 Sec20 BCAS2 PF05700.6 CCU99261.1 - 2.7 7.4 11.2 3.9 6.8 2.7 2.1 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) Tex_N PF09371.5 CCU99261.1 - 3.7 6.8 9.0 0.27 10.5 0.9 2.0 1 1 1 2 2 2 0 Tex-like protein N-terminal domain Rep_fac_C PF08542.6 CCU99263.1 - 0.0052 16.7 0.1 0.02 14.8 0.0 2.0 1 1 0 1 1 1 1 Replication factor C C-terminal domain AA_kinase PF00696.23 CCU99264.1 - 3.2e-37 128.3 0.2 4e-37 128.0 0.2 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 CCU99264.1 - 1.1e-14 53.8 0.1 5.5e-13 48.4 0.0 2.4 2 0 0 2 2 2 1 PUA domain NifZ PF04319.8 CCU99264.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 NifZ domain WD40 PF00400.27 CCU99265.1 - 5.2e-09 35.6 12.8 0.0026 17.5 0.0 8.7 9 1 0 9 9 9 3 WD domain, G-beta repeat PQQ_3 PF13570.1 CCU99265.1 - 0.00022 21.3 0.2 0.0083 16.3 0.0 3.6 3 0 0 3 3 3 1 PQQ-like domain DEAD PF00270.24 CCU99266.1 - 1.4e-36 125.5 0.0 2.7e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU99266.1 - 1.8e-27 94.9 0.0 1.9e-26 91.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCU99266.1 - 0.0014 18.4 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCU99266.1 - 0.066 13.3 1.5 0.99 9.5 0.4 2.9 2 1 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.1 CCU99266.1 - 0.11 12.4 0.0 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 Helicase C-terminal domain Homeobox PF00046.24 CCU99267.1 - 0.035 13.7 1.0 0.071 12.7 0.4 1.8 1 1 1 2 2 2 0 Homeobox domain CTP_transf_2 PF01467.21 CCU99268.1 - 9.4e-30 103.7 0.0 1.1e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase Helicase_C PF00271.26 CCU99269.1 - 6.4e-19 67.6 0.1 1.3e-18 66.5 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCU99269.1 - 8.7e-15 54.6 2.1 1.8e-14 53.6 0.1 2.3 2 1 0 3 3 3 1 DEAD/DEAH box helicase ORC3_N PF07034.6 CCU99270.1 - 2.9e-08 33.0 0.3 0.0018 17.2 0.0 3.3 3 0 0 3 3 3 3 Origin recognition complex (ORC) subunit 3 N-terminus Mito_carr PF00153.22 CCU99271.1 - 1.5e-46 156.0 0.2 2.9e-17 62.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NPR2 PF06218.6 CCU99272.1 - 5.1e-83 279.1 3.0 4.5e-56 190.3 0.2 3.1 2 1 0 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 CCU99272.1 - 1.3e-06 27.2 0.3 6e-06 25.0 0.0 1.9 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_M28 PF04389.12 CCU99273.1 - 2.7e-34 118.4 0.0 3.7e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PTPLA PF04387.9 CCU99275.1 - 1.2e-46 158.1 6.8 1.2e-46 158.1 4.7 1.8 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Glyco_transf_22 PF03901.12 CCU99276.1 - 1.9e-28 99.6 3.1 2.7e-28 99.1 2.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SNF2_N PF00176.18 CCU99277.1 - 1.4e-71 240.7 0.0 1.9e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 CCU99277.1 - 3.6e-17 62.2 0.0 8.1e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 CCU99277.1 - 3e-12 46.2 0.0 8.3e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCU99277.1 - 3.5e-08 33.1 0.0 6.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CCU99277.1 - 2.1e-06 27.7 0.0 3.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 CCU99277.1 - 6.2e-05 22.5 12.8 0.00011 21.7 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCU99277.1 - 0.0025 17.8 15.6 0.0047 16.9 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCU99277.1 - 0.016 14.9 15.6 0.033 14.0 10.8 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 CCU99277.1 - 0.042 13.5 15.3 0.079 12.6 10.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4404 PF14357.1 CCU99277.1 - 0.09 13.1 0.1 0.61 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) zf-RING_5 PF14634.1 CCU99277.1 - 0.13 11.9 14.9 0.25 11.1 10.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain APC10 PF03256.11 CCU99278.1 - 1.1e-38 132.8 0.0 1.5e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Imm44 PF15584.1 CCU99278.1 - 0.065 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 44 DUF3701 PF12482.3 CCU99278.1 - 0.08 12.6 0.2 0.27 10.9 0.1 1.8 2 0 0 2 2 2 0 Phage integrase protein NIF PF03031.13 CCU99279.1 - 7e-26 90.8 0.0 5e-25 88.0 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CCU99279.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 CCU99281.1 - 1.2e-24 85.2 0.7 0.00035 20.3 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat VID27 PF08553.5 CCU99281.1 - 0.061 11.5 0.0 0.095 10.9 0.0 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein GalP_UDP_transf PF01087.17 CCU99282.1 - 1.4e-62 211.0 0.2 1.9e-62 210.6 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 CCU99282.1 - 4.6e-44 149.9 0.0 1.3e-43 148.4 0.0 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain dCMP_cyt_deam_1 PF00383.17 CCU99283.1 - 7.1e-23 80.1 2.0 1.2e-22 79.5 1.4 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 CCU99283.1 - 0.00035 21.3 0.0 0.00076 20.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCU99283.1 - 0.14 12.0 0.1 0.49 10.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCU99283.1 - 0.19 12.0 0.0 0.41 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain JmjC PF02373.17 CCU99285.1 - 1.1e-40 138.3 0.1 1.9e-40 137.6 0.1 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 CCU99285.1 - 3.7e-15 55.1 0.1 6.3e-15 54.3 0.1 1.4 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 CCU99285.1 - 0.0044 17.1 0.1 0.014 15.5 0.1 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CCU99285.1 - 0.024 14.6 0.3 0.064 13.2 0.0 1.8 2 0 0 2 2 2 0 PHD-zinc-finger like domain TPT PF03151.11 CCU99286.1 - 9.5e-09 35.0 5.6 9.5e-09 35.0 3.9 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CCU99286.1 - 0.00039 19.4 11.2 0.0005 19.0 7.8 1.2 1 0 0 1 1 1 1 UAA transporter family Mito_carr PF00153.22 CCU99287.1 - 6.3e-50 166.8 2.0 3.2e-15 55.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 CCU99287.1 - 0.0072 16.2 0.0 4 7.4 0.0 2.7 3 0 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Ras PF00071.17 CCU99288.1 - 5.3e-64 214.4 0.6 6.8e-64 214.1 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU99288.1 - 6.6e-21 75.0 1.0 7.6e-21 74.8 0.0 1.6 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CCU99288.1 - 2.5e-17 62.6 0.1 3.5e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCU99288.1 - 2.4e-06 27.1 0.2 5.7e-06 25.8 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCU99288.1 - 2.4e-06 26.8 0.0 2.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCU99288.1 - 4e-05 22.9 0.0 4.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CCU99288.1 - 4.7e-05 23.3 0.7 8.3e-05 22.5 0.0 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCU99288.1 - 8.7e-05 21.8 0.1 0.00067 18.9 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 CCU99288.1 - 0.00057 20.0 0.0 0.00057 20.0 0.0 1.7 2 1 0 2 2 1 1 AAA domain DUF258 PF03193.11 CCU99288.1 - 0.0015 17.7 0.5 0.026 13.6 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCU99288.1 - 0.0016 17.9 0.2 0.11 12.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.24 CCU99288.1 - 0.0034 17.5 0.1 0.39 10.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCU99288.1 - 0.0076 16.2 0.6 0.05 13.5 0.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CCU99288.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CCU99288.1 - 0.011 16.0 0.6 0.11 12.8 0.4 2.2 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 CCU99288.1 - 0.05 12.6 0.0 0.19 10.7 0.0 1.8 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 CCU99288.1 - 0.064 12.7 0.1 1.1 8.7 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sec7 PF01369.15 CCU99289.1 - 5.1e-59 199.1 0.0 8.2e-59 198.4 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CCU99289.1 - 9.4e-16 57.6 1.5 3.2e-15 55.9 1.0 1.9 1 1 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Med31 PF05669.7 CCU99290.1 - 4.5e-29 100.2 0.4 7.1e-29 99.5 0.2 1.3 1 0 0 1 1 1 1 SOH1 mIF3 PF14877.1 CCU99290.1 - 0.00029 20.2 0.0 0.00054 19.3 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_N PF05198.11 CCU99290.1 - 0.00072 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.17 CCU99290.1 - 0.0045 16.7 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain AAR2 PF05282.6 CCU99291.1 - 3.7e-38 131.4 0.0 1.1e-37 129.8 0.0 1.7 1 1 0 1 1 1 1 AAR2 protein Ribosomal_L2_C PF03947.13 CCU99292.1 - 2.4e-41 140.5 1.3 3.7e-41 139.9 0.9 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCU99292.1 - 1.9e-13 50.1 0.1 3.8e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain EXS PF03124.9 CCU99293.1 - 8e-61 205.9 4.6 9.6e-61 205.7 3.2 1.1 1 0 0 1 1 1 1 EXS family DEAD PF00270.24 CCU99295.1 - 1.2e-37 129.0 0.0 2.1e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CCU99295.1 - 1.9e-17 62.5 0.3 3.2e-17 61.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CCU99295.1 - 2.6e-16 59.2 0.0 5.3e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCU99295.1 - 0.00026 20.8 0.0 0.00042 20.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit La PF05383.12 CCU99296.1 - 1.3e-20 72.9 0.0 2.4e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 CCU99296.1 - 1e-08 35.0 0.0 2.9e-08 33.5 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCU99296.1 - 5.2e-07 29.2 0.4 1.4e-06 27.8 0.3 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99296.1 - 0.00014 21.6 0.2 0.00049 19.8 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCU99296.1 - 0.00055 19.7 0.1 0.0055 16.5 0.0 2.3 2 1 0 2 2 2 1 RNA binding motif Dabb PF07876.7 CCU99296.1 - 0.014 15.8 0.1 0.038 14.4 0.1 1.7 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain VTC PF09359.5 CCU99297.1 - 3.2e-104 347.9 0.1 7e-104 346.8 0.0 1.6 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CCU99297.1 - 2.6e-33 116.0 7.5 2.6e-33 116.0 5.2 3.4 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 CCU99297.1 - 1.9e-10 40.7 3.2 1.9e-10 40.7 2.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1154 PF06631.6 CCU99297.1 - 1.2 8.8 4.5 8.8 6.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) COX15-CtaA PF02628.10 CCU99298.1 - 4.3e-83 278.6 1.8 6.7e-83 278.0 1.3 1.3 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein DUF2116 PF09889.4 CCU99298.1 - 0.0036 17.0 0.0 0.0084 15.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) PepSY_TM_1 PF13172.1 CCU99298.1 - 0.053 13.2 8.8 0.81 9.5 0.1 3.8 3 0 0 3 3 3 0 PepSY-associated TM helix HLH PF00010.21 CCU99299.1 - 1.6e-13 50.1 0.0 2.8e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3166 PF11365.3 CCU99299.1 - 0.13 12.7 1.9 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) AAA PF00004.24 CCU99300.1 - 1.9e-07 31.3 0.0 3.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCU99300.1 - 0.00016 21.7 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCU99300.1 - 0.0094 15.9 0.5 0.049 13.6 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CCU99300.1 - 0.086 13.6 0.0 0.23 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 CCU99300.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 CCU99300.1 - 0.18 11.1 0.0 0.4 10.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 CCU99300.1 - 0.21 10.4 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 CCU99300.1 - 0.24 11.2 0.0 0.51 10.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain DSPn PF14671.1 CCU99302.1 - 1.7e-34 118.8 0.1 4.5e-33 114.2 0.1 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CCU99302.1 - 1e-12 47.8 0.0 1.7e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCU99302.1 - 6.3e-05 22.4 0.0 9.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCU99302.1 - 0.0087 16.1 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CCU99302.1 - 0.088 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family EMG1 PF03587.9 CCU99303.1 - 2.8e-74 248.8 0.0 3.8e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Ank_2 PF12796.2 CCU99304.1 - 9.5e-22 77.1 0.1 5.5e-10 39.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCU99304.1 - 1.7e-20 73.0 1.1 5.3e-12 45.8 0.1 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 CCU99304.1 - 7.3e-20 69.7 0.0 8.8e-08 31.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CCU99304.1 - 6.5e-18 64.3 0.9 5.7e-08 32.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCU99304.1 - 2.4e-17 61.2 0.4 7.1e-05 22.6 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat KilA-N PF04383.8 CCU99304.1 - 1.2e-05 24.9 0.1 4.4e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 KilA-N domain Clp1 PF06807.9 CCU99305.1 - 3.6e-08 33.4 0.0 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 FtsK_SpoIIIE PF01580.13 CCU99305.1 - 0.0063 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family MobB PF03205.9 CCU99305.1 - 0.019 14.6 0.0 0.05 13.3 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mito_carr PF00153.22 CCU99306.1 - 4.7e-49 164.0 1.8 4.8e-21 74.2 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein AIF-MLS PF14962.1 CCU99306.1 - 0.095 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence PMT PF02366.13 CCU99307.1 - 2.6e-75 252.9 16.2 5.3e-75 251.9 11.2 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCU99307.1 - 8.5e-34 116.7 1.5 1.9e-33 115.6 0.3 2.1 2 1 0 2 2 2 1 MIR domain 5-FTHF_cyc-lig PF01812.15 CCU99308.1 - 1.7e-40 138.7 0.0 2e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family ACBP PF00887.14 CCU99309.1 - 1.3e-25 88.8 0.0 2.7e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Peroxin-3 PF04882.7 CCU99310.1 - 4.2e-97 325.6 0.0 4.8e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 ABC_tran PF00005.22 CCU99311.1 - 2e-46 157.6 0.0 3.4e-26 92.1 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCU99311.1 - 2e-18 67.3 0.0 0.0036 17.3 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 CCU99311.1 - 1.2e-10 41.0 0.0 0.00013 21.2 0.0 3.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 CCU99311.1 - 4.1e-08 32.7 0.1 8e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.1 CCU99311.1 - 8.6e-07 29.4 1.1 0.019 15.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCU99311.1 - 1.1e-06 28.0 0.3 0.032 13.7 0.2 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 CCU99311.1 - 3.1e-05 23.2 0.0 0.27 10.2 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 CCU99311.1 - 3.7e-05 23.6 0.0 0.013 15.4 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase Miro PF08477.8 CCU99311.1 - 0.00011 22.6 0.0 0.1 13.0 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein AAA_17 PF13207.1 CCU99311.1 - 0.0003 21.6 0.0 0.16 12.7 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 CCU99311.1 - 0.00031 20.6 0.0 0.14 11.9 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 CCU99311.1 - 0.00046 20.3 0.3 2.4 8.3 0.0 4.0 5 0 0 5 5 3 1 AAA domain SbcCD_C PF13558.1 CCU99311.1 - 0.00071 19.4 0.0 0.33 10.9 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 CCU99311.1 - 0.0011 17.8 2.2 0.074 11.8 0.1 2.9 3 0 0 3 3 3 1 ArgK protein MobB PF03205.9 CCU99311.1 - 0.0011 18.6 0.1 0.2 11.3 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 CCU99311.1 - 0.0014 18.0 0.0 1.8 7.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CCU99311.1 - 0.0016 18.0 0.0 1.9 8.1 0.0 3.1 3 0 0 3 3 3 1 NACHT domain Tudor-knot PF11717.3 CCU99311.1 - 0.002 17.8 0.2 0.0054 16.4 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF258 PF03193.11 CCU99311.1 - 0.0022 17.2 0.0 0.07 12.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 CCU99311.1 - 0.0028 17.5 0.0 0.4 10.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCU99311.1 - 0.0036 17.3 3.6 0.34 10.8 0.1 4.3 3 2 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 CCU99311.1 - 0.0045 16.4 1.4 1.9 7.8 0.1 3.4 3 0 0 3 3 3 1 AAA-like domain Zeta_toxin PF06414.7 CCU99311.1 - 0.006 15.7 0.1 7.5 5.5 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin HEAT_EZ PF13513.1 CCU99311.1 - 0.018 15.4 8.4 1.9 9.0 0.2 5.5 5 1 1 6 6 4 0 HEAT-like repeat AAA_28 PF13521.1 CCU99311.1 - 0.019 14.8 0.0 5.5 6.9 0.0 3.1 2 0 0 2 2 2 0 AAA domain HEAT_2 PF13646.1 CCU99311.1 - 0.022 15.0 12.4 0.2 11.9 1.3 5.0 1 1 3 4 4 4 0 HEAT repeats Dynamin_N PF00350.18 CCU99311.1 - 0.035 13.9 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.17 CCU99311.1 - 0.074 13.2 0.0 1.8 8.8 0.0 2.9 3 0 0 3 3 2 0 RNA helicase cobW PF02492.14 CCU99311.1 - 0.079 12.3 0.1 8.1 5.8 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 CCU99311.1 - 0.087 11.8 0.0 23 3.8 0.0 3.2 3 1 0 3 3 3 0 KAP family P-loop domain WD40 PF00400.27 CCU99312.1 - 3.8e-10 39.2 4.3 2.8e-05 23.8 0.0 3.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Sec63 PF02889.11 CCU99313.1 - 5e-20 71.9 0.0 7e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 CCU99313.1 - 2.1e-16 59.4 0.2 5.4e-16 58.0 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain NOA36 PF06524.7 CCU99313.1 - 2.2 7.4 8.7 3.2 6.9 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein Fumble PF03630.9 CCU99314.1 - 4e-113 377.7 0.0 1.5e-83 280.5 0.0 2.2 2 0 0 2 2 2 2 Fumble Caps_synth_GfcC PF06251.6 CCU99314.1 - 0.061 12.4 0.1 0.095 11.8 0.1 1.2 1 0 0 1 1 1 0 Capsule biosynthesis GfcC Spt4 PF06093.8 CCU99315.1 - 2.1e-25 88.3 0.3 2.5e-25 88.1 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RNA_POL_M_15KD PF02150.11 CCU99315.1 - 0.074 12.7 0.6 9.1 6.0 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Glyco_transf_15 PF01793.11 CCU99317.1 - 2.1e-116 388.5 10.1 2.7e-116 388.1 7.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase TK PF00265.13 CCU99317.1 - 0.27 10.7 0.8 0.42 10.1 0.1 1.5 2 0 0 2 2 2 0 Thymidine kinase RNA_pol_A_bac PF01000.21 CCU99318.1 - 8.3e-19 67.7 0.0 8.4e-18 64.5 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CCU99318.1 - 0.0013 17.7 0.0 0.0019 17.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain BORA_N PF15280.1 CCU99318.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein aurora borealis N-terminus URO-D PF01208.12 CCU99319.1 - 3.7e-123 410.8 0.0 4.3e-123 410.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) TIP49 PF06068.8 CCU99320.1 - 2e-178 593.1 0.1 2.4e-178 592.8 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CCU99320.1 - 1.2e-10 40.9 0.1 7.8e-06 25.0 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CCU99320.1 - 4.6e-10 39.8 1.3 2.3e-05 24.6 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCU99320.1 - 2.1e-06 27.9 0.6 0.11 12.6 0.1 3.4 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.1 CCU99320.1 - 3.6e-05 23.4 0.9 0.00067 19.3 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 CCU99320.1 - 5.1e-05 23.3 0.4 0.072 13.0 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CCU99320.1 - 0.00017 21.2 0.1 0.081 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CCU99320.1 - 0.00037 19.9 0.4 0.00099 18.5 0.3 1.8 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 CCU99320.1 - 0.0017 18.3 0.1 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCU99320.1 - 0.0035 16.7 0.2 0.011 15.1 0.1 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 CCU99320.1 - 0.013 15.0 0.0 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 CCU99320.1 - 0.015 14.4 0.1 0.99 8.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.10 CCU99320.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.4 CCU99320.1 - 0.03 13.3 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 CCU99320.1 - 0.039 13.0 0.2 0.089 11.8 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 CCU99320.1 - 0.047 13.3 0.1 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CCU99320.1 - 0.12 11.9 0.1 0.32 10.6 0.1 1.7 1 0 0 1 1 1 0 NACHT domain IMPDH PF00478.20 CCU99321.1 - 5.6e-137 456.3 0.0 1.2e-121 405.9 0.0 2.0 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CCU99321.1 - 5.6e-18 64.4 0.1 3.6e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 CCU99321.1 - 4.7e-13 48.9 2.1 2.1e-11 43.5 0.6 2.2 2 0 0 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.13 CCU99321.1 - 4.3e-11 42.2 1.3 1.8e-10 40.1 0.7 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 CCU99321.1 - 7.9e-08 31.8 1.2 5.4e-07 29.1 0.8 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.9 CCU99321.1 - 0.00014 20.8 0.1 0.00027 19.9 0.0 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.9 CCU99321.1 - 0.00069 18.7 2.2 0.0014 17.7 0.6 2.0 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.14 CCU99321.1 - 0.014 14.6 0.2 0.043 12.9 0.0 1.8 2 0 0 2 2 2 0 KDPG and KHG aldolase Glu_synthase PF01645.12 CCU99321.1 - 0.032 13.1 1.9 0.056 12.3 1.3 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase PcrB PF01884.12 CCU99321.1 - 0.032 13.4 3.9 0.95 8.6 0.1 3.8 4 1 0 4 4 4 0 PcrB family EAL PF00563.15 CCU99321.1 - 0.054 12.9 0.1 5.6 6.3 0.0 2.2 2 0 0 2 2 2 0 EAL domain G3P_antiterm PF04309.7 CCU99321.1 - 0.087 11.8 0.3 6.8 5.6 0.0 2.5 1 1 1 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Dus PF01207.12 CCU99321.1 - 0.091 11.5 0.3 0.51 9.1 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) TAF4 PF05236.9 CCU99322.1 - 5.1e-27 94.8 0.6 1.3e-26 93.4 0.4 1.7 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family PPR_2 PF13041.1 CCU99323.1 - 2e-35 120.5 0.0 8.4e-12 44.8 0.0 10.1 9 2 2 11 11 11 6 PPR repeat family PPR_3 PF13812.1 CCU99323.1 - 1.9e-27 93.2 17.8 3.3e-05 23.8 0.0 13.0 13 0 0 13 13 13 4 Pentatricopeptide repeat domain PPR PF01535.15 CCU99323.1 - 1.7e-24 84.0 4.8 0.00013 21.7 0.0 12.6 12 2 0 12 12 12 5 PPR repeat PPR_1 PF12854.2 CCU99323.1 - 2.5e-16 58.8 0.1 1.5e-06 27.5 0.0 8.2 9 1 0 9 9 9 3 PPR repeat ECSIT PF06239.6 CCU99323.1 - 0.0027 16.6 0.1 0.96 8.2 0.0 3.3 4 0 0 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway RPM2 PF08579.6 CCU99323.1 - 0.032 14.3 0.0 0.91 9.6 0.0 2.8 3 1 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.1 CCU99323.1 - 1.8 9.4 21.0 4.1 8.3 0.0 8.6 9 1 1 10 10 10 0 Tetratricopeptide repeat RRM_6 PF14259.1 CCU99324.1 - 6.2e-21 74.1 0.0 1.7e-10 40.7 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCU99324.1 - 8.9e-21 73.3 0.0 2e-08 33.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99324.1 - 1.5e-07 31.1 0.0 0.0075 16.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.18 CCU99325.1 - 3.8e-86 288.8 0.0 5.5e-86 288.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Spt5_N PF11942.3 CCU99325.1 - 0.029 14.9 11.4 0.069 13.7 7.9 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF1878 PF08963.5 CCU99325.1 - 0.14 12.3 1.2 0.37 11.0 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) MSA-2c PF12238.3 CCU99325.1 - 1.3 8.6 5.6 8.7 5.9 3.9 2.1 1 1 0 1 1 1 0 Merozoite surface antigen 2c Peptidase_M24 PF00557.19 CCU99326.1 - 1.9e-52 177.8 0.1 2.8e-52 177.3 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CCU99326.1 - 1e-15 57.3 0.0 5.7e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 Aminopeptidase P, N-terminal domain Ribosomal_S4 PF00163.14 CCU99327.1 - 6.8e-12 45.6 1.1 1.1e-11 44.9 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCU99327.1 - 9e-12 44.2 0.0 2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain DUF530 PF04409.7 CCU99327.1 - 0.022 12.8 0.1 0.029 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) Fe_hyd_lg_C PF02906.9 CCU99328.1 - 3.7e-66 223.3 0.0 5.3e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SNARE PF05739.14 CCU99329.1 - 3.2e-18 65.1 4.5 3.2e-18 65.1 3.1 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 CCU99329.1 - 9.4e-07 28.9 8.0 2.1e-06 27.8 1.0 2.7 2 1 1 3 3 3 1 Syntaxin MCPsignal PF00015.16 CCU99329.1 - 0.0002 20.9 6.8 0.00047 19.7 0.3 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain ApoL PF05461.6 CCU99329.1 - 0.011 15.0 2.2 0.013 14.7 1.1 1.4 1 1 0 1 1 1 0 Apolipoprotein L DUF948 PF06103.6 CCU99329.1 - 0.015 15.1 0.6 0.015 15.1 0.4 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Synaptobrevin PF00957.16 CCU99329.1 - 0.088 12.4 0.3 0.088 12.4 0.2 2.4 3 0 0 3 3 3 0 Synaptobrevin gpW PF02831.10 CCU99329.1 - 0.13 11.8 2.1 0.17 11.4 0.3 2.1 2 0 0 2 2 2 0 gpW Med28 PF11594.3 CCU99329.1 - 1.1 9.5 7.7 2.7 8.2 2.0 2.8 1 1 2 3 3 3 0 Mediator complex subunit 28 TMPIT PF07851.8 CCU99329.1 - 1.7 7.6 5.5 5.6 5.9 0.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein NDUF_B7 PF05676.8 CCU99330.1 - 1.1e-19 69.6 1.9 3.1e-19 68.1 1.3 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) XRN_N PF03159.13 CCU99331.1 - 1.9e-99 331.8 0.0 4.3e-99 330.6 0.0 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 CCU99331.1 - 0.00034 20.4 7.5 0.00057 19.6 5.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CCU99331.1 - 0.0093 15.6 1.3 0.02 14.6 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle PMI_typeI PF01238.16 CCU99332.1 - 1.4e-113 379.6 0.0 1.6e-113 379.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 CCU99332.1 - 0.013 14.9 0.0 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Cupin domain AraC_binding PF02311.14 CCU99332.1 - 0.036 13.7 0.0 15 5.2 0.0 2.7 3 0 0 3 3 3 0 AraC-like ligand binding domain DIE2_ALG10 PF04922.7 CCU99333.1 - 1.8e-34 119.3 5.8 2.6e-34 118.8 4.0 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Abhydrolase_3 PF07859.8 CCU99334.1 - 1.8e-58 197.6 0.0 5.2e-28 98.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCU99334.1 - 1e-11 44.4 0.0 0.00021 20.5 0.0 3.6 3 1 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCU99334.1 - 2.1e-09 37.3 0.0 0.0018 18.0 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCU99334.1 - 6.1e-08 32.8 0.0 0.0078 16.1 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family AXE1 PF05448.7 CCU99334.1 - 1.3e-06 27.2 0.0 0.031 12.7 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.13 CCU99334.1 - 4.8e-06 26.0 0.1 0.0018 17.6 0.0 2.5 3 0 0 3 3 3 2 Dienelactone hydrolase family BAAT_C PF08840.6 CCU99334.1 - 0.00018 21.3 0.0 0.51 10.0 0.0 2.4 2 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.4 CCU99334.1 - 0.00068 18.9 0.2 0.85 8.8 0.0 2.7 3 0 0 3 3 3 2 Esterase PHB depolymerase Thioesterase PF00975.15 CCU99334.1 - 0.0013 18.9 0.1 0.16 12.1 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain DUF2974 PF11187.3 CCU99334.1 - 0.0016 17.8 0.0 0.91 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Esterase PF00756.15 CCU99334.1 - 0.012 15.0 0.0 3.2 7.0 0.0 3.0 3 0 0 3 3 3 0 Putative esterase DUF2424 PF10340.4 CCU99334.1 - 0.015 13.9 0.0 4.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Abhydrolase_2 PF02230.11 CCU99334.1 - 0.052 12.9 0.0 2 7.7 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 CCU99334.1 - 0.099 12.1 0.0 10 5.5 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Acetyltransf_1 PF00583.19 CCU99335.1 - 0.0034 17.3 0.1 0.0052 16.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCU99335.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCU99335.1 - 0.066 13.3 0.0 0.11 12.7 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CwfJ_C_1 PF04677.10 CCU99336.1 - 1.2e-28 99.2 0.0 2e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CCU99336.1 - 5.2e-13 49.3 0.1 1.1e-12 48.3 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Cnd1 PF12717.2 CCU99337.1 - 5.7e-61 205.4 1.0 1.6e-55 187.7 0.0 3.5 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 CCU99337.1 - 6.7e-38 130.0 0.0 2.2e-37 128.2 0.0 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 CCU99337.1 - 1.6e-06 28.3 13.6 0.14 12.4 0.1 6.8 6 1 1 7 7 7 2 HEAT repeats HEAT PF02985.17 CCU99337.1 - 7.8e-06 25.5 10.2 0.44 10.7 0.1 7.3 8 0 0 8 8 8 2 HEAT repeat Adaptin_N PF01602.15 CCU99337.1 - 5.6e-05 21.6 0.2 0.014 13.7 0.0 3.0 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 CCU99337.1 - 0.00042 20.7 12.3 0.013 15.9 0.2 6.8 6 1 1 7 7 7 2 HEAT-like repeat Cnd3 PF12719.2 CCU99337.1 - 0.00064 18.7 0.9 0.0019 17.2 0.1 2.1 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 CCU99337.1 - 0.044 13.6 0.5 19 5.2 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HHH_7 PF14635.1 CCU99337.1 - 0.062 13.4 0.0 0.24 11.5 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif PqqD PF05402.7 CCU99337.1 - 0.16 12.0 2.4 1.8 8.6 0.0 3.6 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) Sec62 PF03839.11 CCU99338.1 - 2.3e-44 151.4 6.2 1.1e-43 149.2 4.3 1.8 1 1 0 1 1 1 1 Translocation protein Sec62 Claudin_2 PF13903.1 CCU99338.1 - 0.035 13.8 0.1 0.043 13.5 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Alg6_Alg8 PF03155.10 CCU99339.1 - 1.4e-112 376.9 15.6 2.7e-54 184.7 0.3 3.0 3 0 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family Actin PF00022.14 CCU99340.1 - 1.7e-120 402.0 0.0 1.9e-120 401.8 0.0 1.0 1 0 0 1 1 1 1 Actin UCH PF00443.24 CCU99341.1 - 1.1e-58 198.4 0.2 1.5e-58 198.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCU99341.1 - 2.6e-35 122.3 1.4 6e-35 121.1 0.9 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PC-Esterase PF13839.1 CCU99341.1 - 0.027 14.2 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Peptidase_C98 PF15499.1 CCU99341.1 - 0.044 13.0 0.6 3 7.0 0.4 2.3 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DPBB_1 PF03330.13 CCU99342.1 - 2.1e-08 34.0 0.1 4.1e-08 33.1 0.1 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CCU99342.1 - 4.6e-05 23.0 0.1 7.1e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Barwin family Yippee-Mis18 PF03226.9 CCU99343.1 - 8.2e-17 61.0 2.1 1e-16 60.7 1.4 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.4 CCU99343.1 - 0.032 14.2 3.5 0.074 13.0 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) AlcCBM31 PF11606.3 CCU99343.1 - 0.055 13.4 0.2 0.41 10.6 0.0 2.0 1 1 1 2 2 2 0 Family 31 carbohydrate binding protein DUF3268 PF11672.3 CCU99343.1 - 0.24 11.4 4.7 0.82 9.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3268) GFA PF04828.9 CCU99343.1 - 0.32 10.9 4.2 2 8.4 0.1 2.3 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 CCU99343.1 - 1.5 8.6 4.6 12 5.7 3.2 2.2 1 1 0 1 1 1 0 Double zinc ribbon RIG-I_C-RD PF11648.3 CCU99343.1 - 2.8 7.8 5.9 5.7 6.8 4.1 1.5 1 1 0 1 1 1 0 C-terminal domain of RIG-I zinc_ribbon_2 PF13240.1 CCU99343.1 - 7.1 6.2 6.6 2.4 7.7 0.1 2.5 2 1 0 2 2 2 0 zinc-ribbon domain TIM21 PF08294.6 CCU99344.1 - 9.8e-08 31.7 0.0 9e-05 22.1 0.0 2.5 2 1 0 2 2 2 2 TIM21 Ribosomal_L10 PF00466.15 CCU99345.1 - 1.6e-17 63.2 0.0 2.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 HEAT_2 PF13646.1 CCU99346.1 - 1.7e-36 124.3 11.3 8.1e-14 51.6 0.0 3.3 1 1 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.11 CCU99346.1 - 8.9e-14 50.5 8.1 0.0014 18.9 0.0 7.3 8 0 0 8 8 8 3 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 CCU99346.1 - 3.2e-11 43.3 4.2 0.031 14.7 0.2 5.6 4 2 2 6 6 6 3 HEAT-like repeat HEAT PF02985.17 CCU99346.1 - 6e-09 35.2 4.1 0.44 10.7 0.0 7.7 7 2 0 7 7 7 1 HEAT repeat Arm PF00514.18 CCU99346.1 - 0.0064 16.2 0.4 8.8 6.3 0.0 4.0 4 1 1 5 5 5 1 Armadillo/beta-catenin-like repeat UPF0147 PF03685.8 CCU99346.1 - 0.013 15.3 0.4 1.3 8.9 0.0 3.2 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0147) Cnd1 PF12717.2 CCU99346.1 - 0.094 12.5 0.0 11 5.7 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.1 CCU99346.1 - 0.22 11.8 4.6 3.9 7.8 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat CoA_binding PF02629.14 CCU99347.1 - 5e-28 97.4 1.1 3e-27 94.9 0.3 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 CCU99347.1 - 5.2e-21 74.8 0.0 9.3e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CCU99347.1 - 3.6e-06 26.6 0.0 7.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CCU99347.1 - 0.00013 22.0 0.1 0.00038 20.6 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 CCU99347.1 - 0.0005 20.5 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF605 PF04652.11 CCU99348.1 - 2.3e-49 168.8 5.4 2.9e-17 63.1 0.7 3.0 1 1 2 3 3 3 3 Vta1 like DWNN PF08783.6 CCU99349.1 - 3.9e-31 106.8 0.0 7.3e-31 105.9 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 CCU99349.1 - 3.1e-06 26.5 4.9 1e-05 24.8 3.4 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CCU99349.1 - 8.5e-06 25.4 2.0 1.7e-05 24.5 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 CCU99349.1 - 0.00025 20.9 12.7 0.00025 20.9 8.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 CCU99349.1 - 0.0015 18.2 0.2 0.0045 16.6 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-RING_6 PF14835.1 CCU99349.1 - 0.0089 15.7 3.6 0.0089 15.7 2.5 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 CCU99349.1 - 0.018 14.7 12.7 0.018 14.7 8.8 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CCU99349.1 - 0.035 13.7 13.3 0.069 12.8 9.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCU99349.1 - 0.43 10.5 14.1 0.93 9.4 9.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCHC_5 PF14787.1 CCU99349.1 - 0.78 9.2 5.1 0.33 10.4 0.7 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Gin PF10764.4 CCU99349.1 - 1.3 8.8 6.3 1 9.1 1.3 2.6 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin zf-C3HC4_3 PF13920.1 CCU99349.1 - 1.3 8.7 14.0 0.15 11.7 6.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCU99349.1 - 2.5 7.9 19.1 0.039 13.7 8.3 1.7 2 0 0 2 2 2 0 Ring finger domain Methyltransf_16 PF10294.4 CCU99350.1 - 1.1e-19 70.6 0.0 1.5e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase adh_short PF00106.20 CCU99350.1 - 0.046 13.6 0.3 0.076 12.9 0.2 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Methyltransf_18 PF12847.2 CCU99350.1 - 0.061 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sec8_exocyst PF04048.9 CCU99351.1 - 9e-18 64.2 0.0 1.8e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Zw10 PF06248.8 CCU99351.1 - 0.0098 14.0 0.2 0.018 13.1 0.2 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 DUF2450 PF10475.4 CCU99351.1 - 0.012 14.5 0.0 0.024 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 CCU99351.1 - 0.79 9.5 3.0 2.1 8.2 0.0 3.2 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_S5_C PF03719.10 CCU99352.1 - 1.8e-14 52.7 0.2 5.4e-14 51.2 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 CCU99352.1 - 1.9e-14 53.1 1.6 3.5e-14 52.2 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain RRM_1 PF00076.17 CCU99353.1 - 4.5e-32 109.5 0.0 3.4e-18 65.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99353.1 - 1.5e-25 88.9 0.0 3e-13 49.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99353.1 - 4.1e-10 39.3 0.0 0.00012 21.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCU99353.1 - 0.011 15.6 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Methyltransf_16 PF10294.4 CCU99354.1 - 2.9e-19 69.1 0.0 3.6e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 CCU99354.1 - 0.0002 20.5 0.0 0.00026 20.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 CCU99354.1 - 0.00036 20.2 0.1 0.00073 19.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCU99354.1 - 0.00065 20.2 0.0 0.00091 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain bZIP_1 PF00170.16 CCU99355.1 - 2.2e-09 37.1 12.8 3.8e-08 33.1 4.4 2.3 1 1 1 2 2 2 2 bZIP transcription factor Hap4_Hap_bind PF10297.4 CCU99355.1 - 5.6e-07 29.1 0.5 2e-06 27.4 0.3 2.1 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 DUF4472 PF14739.1 CCU99355.1 - 0.12 12.8 5.3 0.22 11.9 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) bZIP_2 PF07716.10 CCU99355.1 - 0.25 11.1 15.3 0.82 9.5 4.8 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DUF2968 PF11180.3 CCU99355.1 - 0.26 10.6 16.2 0.44 9.8 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) MbeD_MobD PF04899.7 CCU99355.1 - 0.34 10.8 8.1 0.64 9.9 5.0 2.0 1 1 1 2 2 2 0 MbeD/MobD like His_Phos_1 PF00300.17 CCU99356.1 - 7.6e-20 71.5 0.0 1.1e-19 71.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RibD_C PF01872.12 CCU99357.1 - 5.8e-32 110.9 0.0 6.8e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Cyclin_N PF00134.18 CCU99358.1 - 5.8e-08 32.3 0.7 1.5e-07 31.0 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Lyase_1 PF00206.15 CCU99359.1 - 6.3e-22 78.1 0.0 9.3e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 CCU99359.1 - 1.4e-16 60.2 0.0 3.2e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4089 PF13318.1 CCU99359.1 - 0.056 13.7 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) SelR PF01641.13 CCU99360.1 - 2.7e-53 178.9 0.1 3.1e-53 178.6 0.1 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 CCU99360.1 - 0.022 14.7 0.8 0.095 12.7 0.5 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 CCU99360.1 - 0.1 12.4 1.2 0.33 10.7 0.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 CCU99360.1 - 0.13 11.7 3.8 1.6 8.2 0.1 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-Mss51 PF13824.1 CCU99360.1 - 0.27 11.1 4.7 1.7 8.5 0.2 3.1 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 TF_Zn_Ribbon PF08271.7 CCU99360.1 - 2.9 7.3 5.0 1.2 8.5 0.1 2.6 3 0 0 3 3 3 0 TFIIB zinc-binding Evr1_Alr PF04777.8 CCU99361.1 - 4e-29 100.3 3.1 5.5e-29 99.9 2.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Indigoidine_A PF04227.7 CCU99362.1 - 4.8e-54 183.5 0.0 3.2e-53 180.8 0.0 2.0 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.19 CCU99362.1 - 1.8e-22 79.8 0.0 3.2e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Abhydrolase_6 PF12697.2 CCU99363.1 - 4e-28 98.8 0.4 5.4e-28 98.4 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCU99363.1 - 6.3e-17 61.9 0.0 8.7e-16 58.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCU99363.1 - 1.4e-10 41.0 0.0 3.4e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CCU99363.1 - 1e-05 25.8 0.0 2.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 CCU99363.1 - 0.0019 17.8 0.4 0.076 12.5 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 CCU99363.1 - 0.0027 17.1 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 CCU99363.1 - 0.007 15.9 0.0 0.036 13.6 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein DLH PF01738.13 CCU99363.1 - 0.0098 15.1 0.2 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 CCU99363.1 - 0.016 14.6 1.0 0.23 10.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Methyltransf_PK PF05891.7 CCU99364.1 - 9.2e-46 155.8 0.0 1.4e-20 73.5 0.0 3.3 2 2 1 3 3 3 3 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 CCU99364.1 - 0.00013 22.5 0.0 0.0002 21.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCU99364.1 - 0.00025 21.3 0.1 0.0018 18.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCU99364.1 - 0.00052 20.4 0.0 0.0043 17.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCU99364.1 - 0.00069 20.0 0.0 0.028 14.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Anoctamin PF04547.7 CCU99365.1 - 4.2e-70 236.6 0.5 8.7e-70 235.6 0.4 1.4 1 1 0 1 1 1 1 Calcium-activated chloride channel DUF4499 PF14934.1 CCU99365.1 - 0.013 15.4 0.4 1.1 9.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4499) Memo PF01875.12 CCU99367.1 - 3.6e-23 81.8 0.0 4.2e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein ResIII PF04851.10 CCU99368.1 - 1.5e-16 60.7 0.0 3.1e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCU99368.1 - 2.8e-15 56.2 0.0 5.9e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU99368.1 - 1.2e-14 53.9 0.0 2.2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 CCU99368.1 - 4.7e-05 22.5 0.0 8.5e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CCU99368.1 - 0.0004 20.5 0.0 0.0018 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain SNF2_N PF00176.18 CCU99368.1 - 0.00049 19.0 0.0 0.00074 18.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain cobW PF02492.14 CCU99368.1 - 0.00057 19.3 0.1 0.02 14.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 CCU99368.1 - 0.048 13.4 0.1 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 CCU99368.1 - 0.05 12.4 0.0 0.093 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.1 CCU99368.1 - 0.11 12.0 0.1 12 5.3 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA PF00004.24 CCU99368.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hydant_A_N PF05378.8 CCU99368.1 - 0.14 11.6 0.1 0.75 9.2 0.0 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region Cys_Met_Meta_PP PF01053.15 CCU99370.1 - 7.4e-43 146.2 0.0 9.8e-43 145.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CCU99370.1 - 0.0027 16.4 0.0 0.0039 15.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CCU99370.1 - 0.016 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II ApoO PF09769.4 CCU99372.1 - 5.6e-15 55.3 0.2 3e-14 53.0 0.1 1.9 2 0 0 2 2 2 1 Apolipoprotein O DUF4363 PF14276.1 CCU99372.1 - 0.15 11.7 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) PCI PF01399.22 CCU99373.1 - 6.8e-06 26.3 0.1 1.7e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 CCU99373.1 - 0.049 13.3 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TatD_DNase PF01026.16 CCU99374.1 - 2.4e-36 125.2 0.0 3.2e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF3591 PF12157.3 CCU99375.1 - 4.2e-179 595.7 0.1 6.4e-179 595.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 CCU99375.1 - 1.1e-05 25.0 1.5 2.2e-05 24.0 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Med16 PF11635.3 CCU99375.1 - 0.033 12.1 0.2 0.051 11.5 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 16 PQ-loop PF04193.9 CCU99376.1 - 0.011 15.2 0.4 0.039 13.4 0.3 1.9 1 0 0 1 1 1 0 PQ loop repeat ApbA_C PF08546.6 CCU99377.1 - 1.1e-37 128.8 0.0 1.8e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CCU99377.1 - 6.9e-23 80.7 0.0 1.9e-18 66.3 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA CoA_binding_2 PF13380.1 CCU99377.1 - 0.058 13.5 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain SMC_N PF02463.14 CCU99378.1 - 1.8e-25 89.4 0.0 2.7e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCU99378.1 - 4.1e-15 56.6 7.6 4.1e-15 56.6 5.3 4.0 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCU99378.1 - 2.2e-05 23.8 0.0 6.1e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CCU99378.1 - 6.9e-05 22.0 0.1 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 CCU99378.1 - 6.9e-05 22.9 0.4 0.0025 17.8 0.5 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CCU99378.1 - 0.025 14.8 0.0 0.025 14.8 0.0 4.9 3 2 0 3 3 3 0 ABC transporter DUF3040 PF11239.3 CCU99378.1 - 0.06 13.4 2.4 0.36 10.8 1.6 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Abhydrolase_5 PF12695.2 CCU99379.1 - 1.6e-25 89.5 0.0 2.6e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCU99379.1 - 9.1e-23 81.3 1.9 5.9e-21 75.3 1.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCU99379.1 - 5.6e-11 42.4 0.1 4.1e-07 29.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 CCU99379.1 - 3.7e-08 32.2 0.0 0.00011 20.8 0.0 2.7 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 CCU99379.1 - 4.1e-07 29.6 0.0 6.7e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 CCU99379.1 - 2e-06 27.6 0.0 0.00055 19.7 0.0 2.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 CCU99379.1 - 2.5e-06 27.0 0.2 0.004 16.6 0.0 2.5 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 CCU99379.1 - 4e-05 23.0 0.0 0.00053 19.3 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 CCU99379.1 - 0.00027 20.2 0.1 0.56 9.3 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CCU99379.1 - 0.00029 20.4 0.2 0.00073 19.1 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 CCU99379.1 - 0.00032 20.2 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 CCU99379.1 - 0.00036 20.3 0.1 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 CCU99379.1 - 0.0033 16.8 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 CCU99379.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase 6PF2K PF01591.13 CCU99380.1 - 5.1e-54 182.6 0.1 7e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCU99380.1 - 1.6e-19 70.5 0.5 4.8e-19 68.9 0.1 2.1 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CCU99380.1 - 1.6e-10 41.0 1.2 2.5e-10 40.3 0.1 1.9 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 CCU99380.1 - 0.00031 20.4 0.0 0.00062 19.4 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 CCU99380.1 - 0.00075 18.7 0.1 0.0022 17.2 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_19 PF13245.1 CCU99380.1 - 0.0021 17.7 0.0 0.073 12.8 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 CCU99380.1 - 0.0033 16.5 0.0 0.0096 15.0 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CCU99380.1 - 0.0035 17.6 0.0 0.015 15.6 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCU99380.1 - 0.0074 17.0 0.5 0.029 15.1 0.0 2.2 2 2 0 2 2 2 1 AAA domain APS_kinase PF01583.15 CCU99380.1 - 0.012 15.2 0.1 0.031 13.9 0.1 1.7 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.24 CCU99380.1 - 0.035 14.3 0.0 0.16 12.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCU99380.1 - 0.042 13.8 0.5 0.31 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 CCU99380.1 - 0.045 13.3 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CCU99380.1 - 0.11 11.8 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein FRG1 PF06229.7 CCU99381.1 - 2e-11 43.6 0.0 3.6e-09 36.3 0.0 2.2 1 1 1 2 2 2 2 FRG1-like family Fascin PF06268.8 CCU99381.1 - 7.6e-05 22.7 0.0 0.0033 17.4 0.0 2.3 2 0 0 2 2 2 1 Fascin domain OTCace PF00185.19 CCU99382.1 - 7.3e-42 142.9 0.0 1.1e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 CCU99382.1 - 1.9e-41 141.0 0.0 2.8e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GSHPx PF00255.14 CCU99382.1 - 1.7e-36 123.9 0.1 2.7e-36 123.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione peroxidase TAF PF02969.12 CCU99382.1 - 0.0019 18.1 0.0 0.035 14.0 0.0 2.5 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) AhpC-TSA PF00578.16 CCU99382.1 - 0.0024 17.5 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCU99382.1 - 0.0068 15.9 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Redoxin NDK PF00334.14 CCU99383.1 - 5e-55 184.9 0.0 5.6e-55 184.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 CCU99383.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ ABC1 PF03109.11 CCU99384.1 - 9.1e-15 54.6 0.0 1.9e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CCU99384.1 - 0.038 13.3 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 CCU99384.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family ABC_tran PF00005.22 CCU99386.1 - 4.6e-53 179.1 0.0 3.7e-30 105.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCU99386.1 - 7.8e-48 163.2 32.5 9.1e-26 90.8 8.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 CCU99386.1 - 3.3e-09 37.1 2.1 0.73 9.7 0.0 4.7 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 CCU99386.1 - 2.3e-07 30.2 0.2 0.0026 17.0 0.0 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCU99386.1 - 6.1e-06 25.6 0.3 0.13 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CCU99386.1 - 0.00045 20.1 0.5 0.17 11.8 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CCU99386.1 - 0.0007 20.0 0.2 0.47 10.9 0.1 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 CCU99386.1 - 0.0012 18.3 0.1 0.85 8.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CCU99386.1 - 0.0022 17.2 0.3 1.9 7.6 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 CCU99386.1 - 0.011 16.0 4.1 2.4 8.4 0.1 2.9 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 CCU99386.1 - 0.019 14.7 1.0 0.16 11.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Arch_ATPase PF01637.13 CCU99386.1 - 0.046 13.4 0.0 1 9.0 0.0 2.8 2 1 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 CCU99386.1 - 0.054 12.9 2.6 1.6 8.1 0.1 3.4 4 0 0 4 4 4 0 AAA-like domain AAA_16 PF13191.1 CCU99386.1 - 0.057 13.3 6.4 1.6 8.7 0.1 3.5 3 1 0 3 3 3 0 AAA ATPase domain AAA_17 PF13207.1 CCU99386.1 - 0.067 14.0 3.4 9.3 7.0 0.1 3.8 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 CCU99386.1 - 0.14 12.3 2.3 8.1 6.5 0.1 3.6 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 CCU99386.1 - 0.39 10.1 2.3 17 4.7 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PfkB PF00294.19 CCU99387.1 - 8.7e-64 215.5 2.7 1.1e-63 215.1 1.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CCU99387.1 - 1.2e-06 27.9 0.0 3.1e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PCI PF01399.22 CCU99388.1 - 1.9e-16 60.2 0.0 7.4e-16 58.3 0.0 2.1 1 0 0 1 1 1 1 PCI domain SURF1 PF02104.10 CCU99389.1 - 1.2e-41 142.8 0.0 1.5e-40 139.3 0.0 2.0 1 1 0 1 1 1 1 SURF1 family Complex1_51K PF01512.12 CCU99390.1 - 1.4e-46 157.9 0.0 1.9e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 CCU99390.1 - 2.9e-17 61.5 0.1 5.7e-17 60.5 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 CCU99390.1 - 1.2e-08 34.6 0.0 3e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 SLBB domain TIP49 PF06068.8 CCU99392.1 - 1.2e-179 597.1 3.3 1.4e-179 596.9 2.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CCU99392.1 - 1.3e-09 38.3 0.5 3.5e-07 30.4 0.1 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCU99392.1 - 1.9e-08 33.6 1.1 1.8e-05 23.9 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CCU99392.1 - 3.1e-06 26.9 0.4 0.0018 18.0 0.1 3.2 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CCU99392.1 - 1.1e-05 24.6 2.8 0.00015 20.9 0.6 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DnaB_C PF03796.10 CCU99392.1 - 1.4e-05 24.1 0.3 2.4e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 CCU99392.1 - 1.8e-05 24.8 0.0 0.23 11.6 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCU99392.1 - 0.00013 21.9 0.0 0.0007 19.6 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 CCU99392.1 - 0.00042 19.8 0.2 0.26 10.7 0.1 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 CCU99392.1 - 0.0011 18.7 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CCU99392.1 - 0.0033 16.8 0.0 0.0083 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCU99392.1 - 0.0036 17.1 0.0 0.0097 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCU99392.1 - 0.0046 16.0 0.2 0.01 14.9 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_11 PF13086.1 CCU99392.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CCU99392.1 - 0.012 15.0 0.1 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 CCU99392.1 - 0.016 16.0 0.0 0.048 14.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CCU99392.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.11 CCU99392.1 - 0.019 14.2 0.4 0.061 12.5 0.3 1.8 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 CCU99392.1 - 0.029 13.9 0.1 0.085 12.4 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 CCU99392.1 - 0.042 12.8 0.2 0.083 11.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.9 CCU99392.1 - 0.069 13.0 1.7 0.24 11.3 0.2 2.6 3 1 0 3 3 3 0 AAA domain (Cdc48 subfamily) Sipho_tail PF05709.6 CCU99392.1 - 0.07 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Phage tail protein DEAD PF00270.24 CCU99392.1 - 0.072 12.5 1.9 0.084 12.3 0.5 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase Parvo_NS1 PF01057.12 CCU99392.1 - 0.099 11.4 0.1 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ResIII PF04851.10 CCU99392.1 - 0.16 11.8 0.9 0.76 9.5 0.6 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Lgl_C PF08596.5 CCU99394.1 - 7.1e-21 74.1 0.0 1e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CCU99394.1 - 0.00093 18.9 0.0 0.86 9.5 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat AMP-binding PF00501.23 CCU99396.1 - 4.6e-53 180.1 0.1 2.4e-29 101.9 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CCU99396.1 - 5.6e-09 36.8 0.1 1.3e-08 35.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3148 PF11347.3 CCU99396.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) Ank_2 PF12796.2 CCU99397.1 - 1.6e-08 34.7 0.1 0.00062 20.0 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCU99397.1 - 0.00072 19.7 0.1 0.68 10.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCU99397.1 - 0.0017 18.0 0.1 0.34 10.8 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 CCU99397.1 - 0.0072 16.8 0.1 0.021 15.3 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) GFO_IDH_MocA PF01408.17 CCU99398.1 - 8.9e-16 58.4 0.1 1.6e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCU99398.1 - 9.3e-10 38.3 0.0 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Saccharop_dh PF03435.13 CCU99398.1 - 0.056 12.4 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_3 PF03447.11 CCU99398.1 - 0.083 13.2 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Cellulase PF00150.13 CCU99399.1 - 1.4e-16 60.5 2.2 2e-16 60.0 1.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GRASP55_65 PF04495.9 CCU99400.1 - 6.4e-42 142.8 0.0 1e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain GRASP55_65 PF04495.9 CCU99401.1 - 0.053 13.5 0.0 0.068 13.1 0.0 1.1 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain GMC_oxred_N PF00732.14 CCU99402.1 - 2e-68 230.7 2.2 2.5e-68 230.4 1.5 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCU99402.1 - 2e-36 125.4 0.0 4.2e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCU99402.1 - 1e-06 27.8 0.0 0.00031 19.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCU99402.1 - 1.2e-05 25.4 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCU99402.1 - 0.0001 21.3 1.5 0.0067 15.3 0.8 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 CCU99402.1 - 0.0001 22.2 0.7 0.00037 20.4 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCU99402.1 - 0.0001 22.2 0.1 0.002 18.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCU99402.1 - 0.00017 20.6 0.0 0.00027 19.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 CCU99402.1 - 0.00041 18.9 0.9 0.0089 14.5 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 CCU99402.1 - 0.014 14.5 0.9 0.038 13.0 0.1 2.0 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 CCU99402.1 - 0.023 13.7 0.1 0.038 13.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 CCU99402.1 - 0.043 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 CCU99402.1 - 0.049 14.0 0.5 0.23 11.8 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UPF0029 PF01205.14 CCU99404.1 - 5e-25 87.3 0.0 1.1e-24 86.2 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 CCU99404.1 - 5.3e-06 26.3 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 RWD domain Prok-E2_E PF14462.1 CCU99404.1 - 0.041 13.4 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E Pkinase PF00069.20 CCU99405.1 - 7.4e-10 38.4 0.0 1.6e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99405.1 - 1.1e-07 31.2 0.0 2.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RabGAP-TBC PF00566.13 CCU99406.1 - 2.8e-50 170.7 0.3 4.6e-50 170.0 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 CCU99406.1 - 5.5e-05 22.5 0.0 0.00012 21.4 0.0 1.6 1 0 0 1 1 1 1 GRAM domain DUF3813 PF12758.2 CCU99406.1 - 0.11 12.6 0.1 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) FA_hydroxylase PF04116.8 CCU99407.1 - 2.2e-16 60.2 20.2 2.2e-16 60.2 14.0 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Aa_trans PF01490.13 CCU99408.1 - 1.5e-68 231.2 26.8 1.9e-68 230.8 18.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NTF2 PF02136.15 CCU99410.1 - 2.1e-08 34.5 0.0 2.9e-07 30.8 0.0 2.2 1 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 CCU99410.1 - 3.6e-07 30.0 0.0 8e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 DUF383 PF04063.9 CCU99411.1 - 1.4e-57 194.3 0.0 9.5e-57 191.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 CCU99411.1 - 4.8e-19 67.6 0.3 1.1e-18 66.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Ank_2 PF12796.2 CCU99413.1 - 8.5e-42 141.4 0.4 6.2e-20 71.3 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CCU99413.1 - 9.9e-37 122.9 9.2 1.5e-09 37.1 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat zf-DHHC PF01529.15 CCU99413.1 - 3.1e-29 101.5 7.6 3.1e-29 101.5 5.3 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.1 CCU99413.1 - 6.9e-29 99.2 6.9 1.4e-08 34.6 0.1 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCU99413.1 - 1.7e-25 88.8 4.6 5.4e-11 42.6 0.2 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCU99413.1 - 1.3e-23 80.7 2.3 1.3e-06 28.0 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat DUF2892 PF11127.3 CCU99413.1 - 2 8.2 9.7 0.61 9.9 3.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Biotin_lipoyl PF00364.17 CCU99414.1 - 4.9e-17 61.3 1.5 8.7e-17 60.5 1.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CCU99414.1 - 1.2e-05 24.8 0.0 4.1e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CCU99414.1 - 0.00035 20.1 1.6 0.0017 17.9 0.1 2.6 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_2 PF12700.2 CCU99414.1 - 0.023 13.8 0.4 3.1 6.8 0.1 2.1 1 1 1 2 2 2 0 HlyD family secretion protein HXXSHH PF07586.6 CCU99414.1 - 0.13 11.1 0.6 0.17 10.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) Diphthamide_syn PF01866.12 CCU99415.1 - 1.2e-84 284.1 0.0 4.5e-54 183.7 0.0 2.9 1 1 1 2 2 2 2 Putative diphthamide synthesis protein COQ7 PF03232.8 CCU99416.1 - 8.1e-54 181.6 0.4 1.2e-53 181.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 CCU99416.1 - 0.0026 18.0 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 Rubrerythrin Peptidase_M9_N PF08453.5 CCU99416.1 - 0.0087 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M9 N-terminal DUF3380 PF11860.3 CCU99416.1 - 0.041 13.9 0.0 4.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3380) SMC_hinge PF06470.8 CCU99416.1 - 0.084 12.8 0.1 0.85 9.5 0.0 2.3 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain Med9 PF07544.8 CCU99416.1 - 0.1 12.3 0.2 0.31 10.7 0.1 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF3849 PF12960.2 CCU99416.1 - 0.11 12.4 0.0 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3849) Mito_carr PF00153.22 CCU99417.1 - 1.1e-32 111.6 7.0 1.4e-14 53.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Dak1 PF02733.12 CCU99418.1 - 1.3e-111 372.2 0.7 1.7e-111 371.8 0.5 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 CCU99418.1 - 2.6e-49 167.2 1.7 4.4e-49 166.4 1.1 1.4 1 0 0 1 1 1 1 DAK2 domain Pep3_Vps18 PF05131.9 CCU99419.1 - 9e-27 93.3 0.0 7.2e-26 90.3 0.0 2.3 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CCU99419.1 - 0.00023 20.8 0.3 0.0024 17.4 0.1 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 CCU99419.1 - 0.0035 17.1 2.0 0.0035 17.1 1.4 3.2 3 0 0 3 3 3 1 Ring finger domain Vps39_2 PF10367.4 CCU99419.1 - 0.0067 16.5 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.2 CCU99419.1 - 0.11 12.5 3.4 0.09 12.9 0.4 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger DUF1664 PF07889.7 CCU99419.1 - 0.13 12.0 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-Apc11 PF12861.2 CCU99419.1 - 0.95 9.3 3.9 0.44 10.4 0.3 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CCU99419.1 - 2.2 8.0 9.7 0.028 14.1 1.2 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCU99419.1 - 3.3 7.8 7.2 0.43 10.6 1.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 CCU99420.1 - 1.1e-21 75.8 6.0 0.00069 19.4 0.0 7.1 8 0 0 8 8 8 5 WD domain, G-beta repeat Ssl1 PF04056.9 CCU99421.1 - 6.3e-25 87.8 0.0 1.5e-24 86.6 0.0 1.6 1 1 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 CCU99421.1 - 0.00099 19.2 0.0 0.0027 17.8 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain RD3 PF14473.1 CCU99421.1 - 0.015 14.7 0.2 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 RD3 protein DUF1212 PF06738.7 CCU99422.1 - 1.3e-38 132.4 1.4 1.3e-38 132.4 1.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CCU99422.1 - 1.2e-15 57.5 9.1 1.2e-15 57.5 6.3 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) DUF3339 PF11820.3 CCU99422.1 - 0.12 12.7 3.5 0.062 13.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3339) zf-CHCC PF10276.4 CCU99423.1 - 7.1e-10 38.5 0.0 1.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger domain Ribophorin_I PF04597.9 CCU99425.1 - 8.9e-75 251.8 0.0 1e-74 251.6 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I RRM_1 PF00076.17 CCU99426.1 - 1.3e-17 63.1 0.0 2.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99426.1 - 5.1e-14 52.0 0.1 9.6e-14 51.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99426.1 - 5.7e-08 32.5 0.0 9.6e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF724 PF05266.9 CCU99426.1 - 0.0044 16.6 1.2 0.0061 16.2 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.7 CCU99426.1 - 0.046 13.4 0.5 0.062 13.0 0.3 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 CCU99426.1 - 0.084 12.3 0.5 0.13 11.7 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.10 CCU99426.1 - 0.12 12.1 2.8 0.21 11.4 2.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Caprin-1_C PF12287.3 CCU99426.1 - 9.1 5.5 7.6 15 4.8 5.3 1.3 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Aminotran_5 PF00266.14 CCU99427.1 - 1.4e-76 257.6 0.0 3.1e-76 256.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCU99427.1 - 0.0026 16.9 0.1 0.011 14.9 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase WD40 PF00400.27 CCU99428.1 - 4.2e-33 112.0 12.6 3.1e-08 33.1 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 CCU99428.1 - 3.2e-05 23.7 0.0 3.9 7.1 0.0 4.1 3 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCU99428.1 - 0.012 13.7 0.2 0.093 10.8 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 IKI3 PF04762.7 CCU99428.1 - 0.014 13.2 0.0 0.37 8.5 0.0 2.2 2 0 0 2 2 2 0 IKI3 family PD40 PF07676.7 CCU99428.1 - 0.08 12.6 3.6 5.1 6.8 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 CCU99428.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain MIS13 PF08202.6 CCU99429.1 - 8.8e-20 70.9 7.4 1.7e-18 66.7 5.1 2.3 1 1 0 1 1 1 1 Mis12-Mtw1 protein family HA2 PF04408.18 CCU99430.1 - 5.3e-16 58.5 0.1 2.1e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCU99430.1 - 7.2e-12 45.0 0.0 2.1e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 CCU99430.1 - 1.1e-11 45.1 0.0 4e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.11 CCU99430.1 - 5.3e-07 29.4 0.0 1.5e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CCU99430.1 - 2.2e-05 24.0 0.1 4.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase LRR_6 PF13516.1 CCU99431.1 - 7.2e-05 22.4 0.0 0.31 11.2 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 CCU99431.1 - 0.004 17.0 0.3 64 4.4 0.0 5.2 5 0 0 5 5 5 1 Leucine rich repeat WD40 PF00400.27 CCU99432.1 - 4.7e-41 137.2 12.6 5e-06 26.1 0.0 9.8 9 0 0 9 9 9 8 WD domain, G-beta repeat CTP_transf_2 PF01467.21 CCU99432.1 - 1.1e-07 32.0 0.1 8.6e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Cytidylyltransferase BBS2_Mid PF14783.1 CCU99432.1 - 0.21 11.3 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region FAD_syn PF06574.7 CCU99432.1 - 0.29 10.7 0.1 0.53 9.9 0.1 1.4 1 0 0 1 1 1 0 FAD synthetase HA2 PF04408.18 CCU99434.1 - 2.9e-26 91.4 0.1 3.8e-24 84.6 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCU99434.1 - 1.3e-24 86.2 0.0 3.7e-24 84.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCU99434.1 - 4.8e-13 48.7 0.0 9.8e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCU99434.1 - 4.1e-06 26.4 0.0 9e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCU99434.1 - 3.7e-05 23.8 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCU99434.1 - 0.00016 20.6 0.0 0.00033 19.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 CCU99434.1 - 0.0042 16.8 0.1 0.014 15.0 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCU99434.1 - 0.018 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 CCU99434.1 - 0.034 13.5 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.7 CCU99434.1 - 0.076 12.6 0.2 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 CCU99434.1 - 0.086 12.8 2.7 0.18 11.7 0.0 2.7 1 1 1 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CCU99434.1 - 0.11 11.9 1.8 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.17 CCU99434.1 - 0.12 11.2 0.0 0.64 8.8 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.15 CCU99434.1 - 0.14 10.7 0.0 0.25 9.9 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit PhoH PF02562.11 CCU99434.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 CCU99434.1 - 0.19 10.8 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 KaiC zf-HC5HC2H_2 PF13832.1 CCU99435.1 - 1.6e-33 114.9 3.3 1.6e-33 114.9 2.3 3.0 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CCU99435.1 - 1.1e-25 89.5 0.8 1.1e-25 89.5 0.6 3.3 4 0 0 4 4 4 1 PHD-like zinc-binding domain EPL1 PF10513.4 CCU99435.1 - 1.7e-20 73.8 7.2 1.9e-20 73.7 3.8 1.9 2 0 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 CCU99435.1 - 7.1e-15 54.0 2.9 7.1e-15 54.0 2.0 3.1 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 CCU99435.1 - 4.6e-09 35.8 26.1 1.1e-08 34.5 6.4 3.1 3 0 0 3 3 3 2 PHD-finger Bromodomain PF00439.20 CCU99435.1 - 7.3e-08 32.2 0.0 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain C1_1 PF00130.17 CCU99435.1 - 0.0083 15.8 1.0 0.0083 15.8 0.7 3.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 CCU99435.1 - 0.014 14.6 2.3 0.014 14.6 1.6 2.9 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain AAA PF00004.24 CCU99436.1 - 2.3e-52 176.6 0.0 8.3e-42 142.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCU99436.1 - 6.1e-08 32.8 5.1 6.9e-06 26.1 0.0 4.2 3 1 1 4 4 4 1 AAA ATPase domain IstB_IS21 PF01695.12 CCU99436.1 - 7.1e-07 28.8 0.0 8.8e-05 21.9 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 CCU99436.1 - 4.3e-06 26.8 0.0 0.1 12.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_2 PF07724.9 CCU99436.1 - 1.5e-05 24.9 0.0 3.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCU99436.1 - 2.3e-05 24.5 0.0 0.0076 16.3 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 CCU99436.1 - 4.8e-05 23.1 0.1 0.013 15.2 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCU99436.1 - 0.00051 19.7 1.3 0.0048 16.6 0.1 3.1 3 0 0 3 3 2 1 Part of AAA domain RuvB_N PF05496.7 CCU99436.1 - 0.0017 17.4 0.0 0.42 9.6 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CCU99436.1 - 0.0026 18.0 1.1 0.021 15.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 CCU99436.1 - 0.0035 17.2 0.2 0.023 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCU99436.1 - 0.0038 18.0 0.1 0.027 15.2 0.0 2.6 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CCU99436.1 - 0.0054 16.1 1.5 0.011 15.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCU99436.1 - 0.0055 15.9 0.1 0.19 10.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCU99436.1 - 0.015 14.8 0.0 0.91 8.9 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain TIP49 PF06068.8 CCU99436.1 - 0.025 13.3 0.0 0.082 11.6 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus Parvo_NS1 PF01057.12 CCU99436.1 - 0.029 13.2 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 CCU99436.1 - 0.034 13.7 0.0 0.33 10.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CCU99436.1 - 0.035 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 CCU99436.1 - 0.039 13.8 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CCU99436.1 - 0.048 12.8 0.1 0.25 10.5 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 CCU99436.1 - 0.048 12.6 0.0 0.098 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.6 CCU99436.1 - 0.05 13.4 0.0 0.62 9.9 0.0 2.3 2 0 0 2 2 2 0 Torsin Bromodomain PF00439.20 CCU99436.1 - 0.14 12.0 0.1 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Bromodomain ABC_tran PF00005.22 CCU99436.1 - 0.2 11.9 0.0 0.52 10.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.1 CCU99436.1 - 1.5 8.2 0.0 1.5 8.2 0.0 3.1 4 0 0 4 4 3 0 AAA domain DnaJ PF00226.26 CCU99437.1 - 2.6e-26 91.1 2.3 3.8e-26 90.6 1.6 1.2 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCU99437.1 - 8.1e-13 48.0 0.3 2.3e-10 40.2 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain Ribosomal_L7Ae PF01248.21 CCU99438.1 - 4.4e-27 93.4 0.2 5.7e-27 93.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CCU99438.1 - 0.0031 17.3 0.1 0.0035 17.2 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 CCU99438.1 - 0.039 13.7 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Herpes_U34 PF04541.8 CCU99438.1 - 0.096 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus virion protein U34 CRAL_TRIO PF00650.15 CCU99439.1 - 2.3e-28 98.6 0.0 3.8e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCU99439.1 - 7.4e-11 42.0 0.3 2e-10 40.6 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CCU99439.1 - 1.6e-08 34.5 0.0 2.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain K167R PF08065.7 CCU99439.1 - 0.14 12.2 0.4 13 5.9 0.0 2.6 2 0 0 2 2 2 0 K167R (NUC007) repeat Dimerisation PF08100.6 CCU99439.1 - 0.17 11.7 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Lipase_3 PF01764.20 CCU99440.1 - 7.3e-23 80.7 0.0 1e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 CCU99440.1 - 0.00092 18.5 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 CCU99440.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 CCU99440.1 - 0.013 13.7 0.0 0.018 13.3 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 CCU99440.1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 CCU99440.1 - 0.036 13.4 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) VirJ PF06057.6 CCU99440.1 - 0.058 13.1 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PGAP1 PF07819.8 CCU99440.1 - 0.14 11.6 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 CCU99441.1 - 1.5e-19 70.0 0.0 2e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PAF-AH_p_II PF03403.8 CCU99441.1 - 0.0015 16.9 0.0 0.0023 16.2 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II DUF2974 PF11187.3 CCU99441.1 - 0.0025 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 CCU99441.1 - 0.0029 17.5 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCU99441.1 - 0.021 14.2 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.8 CCU99441.1 - 0.034 13.5 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CCU99441.1 - 0.061 13.0 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.3 CCU99441.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PFK PF00365.15 CCU99442.1 - 8.2e-141 467.9 0.0 1.3e-78 263.8 0.0 3.2 3 0 0 3 3 3 3 Phosphofructokinase OmpA PF00691.15 CCU99442.1 - 0.17 12.2 0.0 0.92 9.9 0.0 2.1 2 0 0 2 2 2 0 OmpA family LSM PF01423.17 CCU99443.1 - 3.5e-15 55.3 0.4 4.4e-15 54.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain CCT_2 PF09425.5 CCU99443.1 - 0.076 12.5 0.2 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Divergent CCT motif PROCN PF08083.6 CCU99444.1 - 1.2e-211 702.5 3.2 9e-211 699.5 3.1 1.8 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CCU99444.1 - 2.5e-125 416.3 0.5 4e-125 415.7 0.3 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CCU99444.1 - 2.1e-90 300.2 0.6 5.4e-90 298.8 0.4 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CCU99444.1 - 1.9e-78 261.3 3.2 1.9e-78 261.3 2.2 2.2 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CCU99444.1 - 5.4e-66 220.3 0.0 1.6e-65 218.8 0.0 1.8 2 0 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 CCU99444.1 - 6.9e-42 141.2 0.3 1.6e-41 140.0 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 CCU99444.1 - 2.5e-32 111.2 0.0 4.9e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 CCU99444.1 - 0.00014 21.5 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3402 PF11882.3 CCU99446.1 - 7.9e-111 370.9 0.0 4.1e-110 368.6 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 CCU99446.1 - 2.9e-18 65.7 0.0 6e-09 35.1 0.0 3.2 3 0 0 3 3 3 3 N1221-like protein DDOST_48kD PF03345.9 CCU99447.1 - 1.1e-95 320.6 0.0 2.8e-95 319.3 0.0 1.6 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta ATP_bind_4 PF01902.12 CCU99448.1 - 4.5e-36 124.2 0.0 1.4e-25 89.9 0.0 2.1 2 0 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 CCU99448.1 - 4.3e-16 58.7 0.0 3e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP SUV3_C PF12513.3 CCU99449.1 - 9.5e-15 53.7 0.2 1.9e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CCU99449.1 - 1.9e-13 50.0 0.3 2.1e-12 46.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromo_TP PF07524.8 CCU99450.1 - 7.1e-05 22.4 0.1 0.00017 21.2 0.1 1.6 1 0 0 1 1 1 1 Bromodomain associated PPE PF00823.14 CCU99450.1 - 2 8.2 8.3 0.067 13.0 0.6 2.3 3 0 0 3 3 3 0 PPE family Peptidase_S10 PF00450.17 CCU99452.1 - 1.5e-38 133.0 0.9 1.7e-27 96.6 0.0 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase FA_desaturase PF00487.19 CCU99453.1 - 1.8e-15 57.1 18.3 3.2e-15 56.2 12.7 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CCU99453.1 - 1.1e-13 50.7 0.1 2.3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_hydro_47 PF01532.15 CCU99455.1 - 4.9e-139 463.8 0.0 6.3e-139 463.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HAD_2 PF13419.1 CCU99455.1 - 4.7e-21 75.7 3.4 7e-21 75.2 1.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCU99455.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Rap_GAP PF02145.10 CCU99456.1 - 3.1e-49 166.9 0.0 6.5e-49 165.8 0.0 1.5 2 0 0 2 2 2 1 Rap/ran-GAP DUF3384 PF11864.3 CCU99456.1 - 4.3e-30 104.6 0.0 8.4e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Tuberin PF03542.11 CCU99456.1 - 1e-27 97.1 2.4 1.6e-26 93.2 1.7 2.7 1 1 0 1 1 1 1 Tuberin Redoxin PF08534.5 CCU99457.1 - 2.7e-36 124.3 0.1 3e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CCU99457.1 - 1.7e-10 40.6 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family LSM PF01423.17 CCU99458.1 - 8.3e-17 60.4 0.1 1e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCU99458.1 - 0.00018 21.3 0.2 0.0003 20.6 0.1 1.4 1 1 0 1 1 1 1 Ataxin 2 SM domain GRDB PF07355.7 CCU99458.1 - 0.079 11.8 0.0 0.083 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) DUF3395 PF11875.3 CCU99459.1 - 1.1e-35 122.4 0.0 1.9e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 CCU99459.1 - 2.2e-22 78.5 1.8 4.3e-22 77.6 1.3 1.5 1 0 0 1 1 1 1 DnaJ domain PAPS_reduct PF01507.14 CCU99460.1 - 6.2e-42 143.3 0.0 7.9e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ribosomal_L4 PF00573.17 CCU99461.1 - 4.9e-44 150.0 0.5 7.5e-44 149.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CCU99461.1 - 1.2e-27 95.5 0.7 1.2e-27 95.5 0.5 2.8 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain COesterase PF00135.23 CCU99462.1 - 2.4e-62 211.3 0.7 6.3e-62 209.9 0.4 1.6 1 1 1 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCU99462.1 - 0.02 14.4 0.0 0.078 12.5 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Pyr_redox_2 PF07992.9 CCU99463.1 - 4.9e-26 91.8 0.1 5.9e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCU99463.1 - 1.6e-15 57.2 0.1 9.1e-13 48.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCU99463.1 - 3.4e-08 33.7 0.0 0.00038 20.5 0.0 3.0 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCU99463.1 - 4.3e-06 25.9 0.0 4e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 CCU99463.1 - 8.5e-06 25.0 1.5 0.0069 15.5 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 CCU99463.1 - 4.3e-05 22.5 0.1 0.04 12.8 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 CCU99463.1 - 8.3e-05 21.6 2.8 0.0037 16.2 1.9 3.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 CCU99463.1 - 0.00021 20.3 4.2 0.0052 15.7 0.4 3.3 3 1 1 4 4 4 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CCU99463.1 - 0.00051 20.0 0.5 0.005 16.8 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCU99463.1 - 0.00066 18.6 2.4 0.0016 17.3 0.3 2.3 2 1 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 CCU99463.1 - 0.0046 16.0 0.2 0.034 13.2 0.0 2.1 2 1 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 CCU99463.1 - 0.0068 16.6 0.1 0.19 12.0 0.0 2.7 3 1 0 3 3 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 CCU99463.1 - 0.015 15.3 0.1 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 CCU99463.1 - 0.015 13.7 0.1 0.053 11.9 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 CCU99463.1 - 0.016 13.8 0.2 0.069 11.7 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Glucosamine_iso PF01182.15 CCU99463.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase AlaDh_PNT_C PF01262.16 CCU99463.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aconitase PF00330.15 CCU99464.1 - 3.2e-170 566.6 0.0 6.6e-170 565.5 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCU99464.1 - 8e-45 152.1 0.0 1.4e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain CS PF04969.11 CCU99465.1 - 4.1e-06 27.2 0.1 7.3e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 CS domain RRM_1 PF00076.17 CCU99466.1 - 8.8e-18 63.7 0.0 1.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99466.1 - 1.4e-13 50.6 0.0 3.1e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99466.1 - 7.3e-10 38.5 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_phi PF04931.8 CCU99466.1 - 0.86 7.2 15.0 1.2 6.7 10.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.3 CCU99466.1 - 2.5 7.9 14.9 5.3 6.9 8.3 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Tom22 PF04281.8 CCU99466.1 - 7.3 6.1 9.3 15 5.1 6.5 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PRMT5 PF05185.11 CCU99467.1 - 2.6e-145 484.7 0.0 3.3e-145 484.4 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 CCU99467.1 - 0.0021 18.5 0.0 0.004 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCU99467.1 - 0.0023 17.9 0.0 0.0071 16.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCU99467.1 - 0.017 15.6 0.0 0.055 13.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_20 PF12147.3 CCU99467.1 - 0.039 12.8 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase AP_endonuc_2 PF01261.19 CCU99467.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Acetyltransf_1 PF00583.19 CCU99468.1 - 2.3e-13 49.9 0.0 4.1e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCU99468.1 - 3.6e-06 27.0 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCU99468.1 - 0.0001 21.9 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CCU99468.1 - 0.00012 22.1 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCU99468.1 - 0.0038 17.1 0.0 0.0056 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCU99468.1 - 0.075 13.1 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCU99468.1 - 0.091 12.6 0.0 0.3 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Actin PF00022.14 CCU99469.1 - 6.2e-85 284.9 0.0 8.4e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 Actin Robl_LC7 PF03259.12 CCU99469.1 - 0.16 11.5 0.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Roadblock/LC7 domain DUF1741 PF08427.5 CCU99469.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) XRN_N PF03159.13 CCU99472.1 - 2.8e-76 256.0 0.0 5.3e-76 255.1 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Imm27 PF15573.1 CCU99472.1 - 0.0091 15.2 0.5 0.016 14.4 0.4 1.3 1 0 0 1 1 1 1 Immunity protein 27 Patatin PF01734.17 CCU99473.1 - 3.7e-16 59.6 0.1 2.8e-12 46.9 0.2 2.7 1 1 1 2 2 2 2 Patatin-like phospholipase DUF3336 PF11815.3 CCU99473.1 - 1.4e-10 40.8 0.0 2.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) AIP3 PF03915.8 CCU99474.1 - 1.9e-95 320.2 0.4 2.1e-95 320.1 0.2 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 Syntaxin-6_N PF09177.6 CCU99474.1 - 0.0038 17.5 4.0 2.9 8.3 0.2 4.0 2 1 2 4 4 4 2 Syntaxin 6, N-terminal Baculo_p24 PF05073.7 CCU99474.1 - 0.077 12.5 0.1 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 Baculovirus P24 capsid protein DUF948 PF06103.6 CCU99474.1 - 1.3 8.9 4.0 2.2 8.1 0.4 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CorA PF01544.13 CCU99474.1 - 3.7 6.5 7.7 0.72 8.8 1.3 2.3 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Helicase_C_3 PF13625.1 CCU99475.1 - 4.3e-27 94.4 0.0 1.3e-26 92.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCU99475.1 - 1e-14 54.7 0.0 1.9e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCU99475.1 - 7.6e-14 51.1 0.1 1.2e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCU99475.1 - 1.8e-11 43.7 0.1 6.4e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCU99475.1 - 5.6e-08 32.4 0.1 1.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SHR3_chaperone PF08229.6 CCU99476.1 - 1.1e-13 50.5 1.2 3.5e-13 48.9 0.9 1.7 1 1 0 1 1 1 1 ER membrane protein SH3 Reprolysin PF01421.14 CCU99476.1 - 0.091 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Pex24p PF06398.6 CCU99476.1 - 0.12 11.1 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Aldo_ket_red PF00248.16 CCU99477.1 - 4.6e-52 176.6 0.1 5.4e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Sad1_UNC PF07738.8 CCU99478.1 - 2.3e-31 108.3 0.0 1.6e-28 99.2 0.0 2.3 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal IncA PF04156.9 CCU99478.1 - 2.8e-05 23.8 0.8 2.8e-05 23.8 0.5 2.9 3 0 0 3 3 3 1 IncA protein EzrA PF06160.7 CCU99478.1 - 0.014 13.6 7.1 0.061 11.5 4.9 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA FH2 PF02181.18 CCU99478.1 - 0.017 14.0 0.6 3.2 6.5 0.1 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain Reo_sigmaC PF04582.7 CCU99478.1 - 0.023 13.9 2.1 0.2 10.8 1.3 2.1 1 1 0 1 1 1 0 Reovirus sigma C capsid protein CTK3 PF12243.3 CCU99478.1 - 0.04 13.5 0.2 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Matrilin_ccoil PF10393.4 CCU99478.1 - 0.14 11.5 5.8 5.5 6.4 0.1 3.9 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin CENP-F_leu_zip PF10473.4 CCU99478.1 - 0.17 11.7 11.5 0.29 10.9 2.0 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 CCU99478.1 - 0.17 11.6 3.9 2.8 7.6 0.1 2.6 2 0 0 2 2 2 0 Laminin Domain II Prefoldin_2 PF01920.15 CCU99478.1 - 0.25 11.0 9.5 0.25 11.1 0.2 3.2 4 0 0 4 4 4 0 Prefoldin subunit Fib_alpha PF08702.5 CCU99478.1 - 0.59 10.2 8.8 0.36 10.9 1.7 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family CCDC-167 PF15188.1 CCU99478.1 - 0.64 9.9 4.0 0.91 9.5 0.2 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Y_phosphatase2 PF03162.8 CCU99479.1 - 3.9e-25 88.1 0.0 6.3e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CCU99479.1 - 0.24 10.7 0.0 0.44 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Brr6_like_C_C PF10104.4 CCU99480.1 - 3.3e-27 94.6 2.4 8.9e-20 70.5 0.0 2.1 1 1 1 2 2 2 2 Di-sulfide bridge nucleocytoplasmic transport domain DNA_pol_A PF00476.15 CCU99481.1 - 4.5e-84 282.2 0.0 7e-84 281.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 CCU99481.1 - 0.1 12.0 0.0 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 3'-5' exonuclease DNA_pol_A PF00476.15 CCU99482.1 - 0.0035 16.0 0.0 0.0059 15.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family A RA PF00788.18 CCU99482.1 - 0.027 14.9 0.0 0.07 13.6 0.0 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Pyr_redox_3 PF13738.1 CCU99484.1 - 5.1e-24 85.4 0.0 2.1e-23 83.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCU99484.1 - 1.3e-19 69.8 0.0 9.4e-19 66.9 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.22 CCU99484.1 - 8.3e-12 45.3 0.8 4.4e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCU99484.1 - 2.1e-11 44.0 0.0 7.9e-06 25.8 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCU99484.1 - 2.6e-10 40.1 1.6 9.9e-09 35.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCU99484.1 - 2.3e-09 36.6 0.4 8.9e-07 28.1 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 CCU99484.1 - 4.3e-09 35.7 0.0 1.9e-06 27.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 CCU99484.1 - 1.8e-06 27.3 0.0 1.3e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 CCU99484.1 - 4.4e-06 26.5 2.8 0.00022 21.0 0.0 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 CCU99484.1 - 1.3e-05 25.3 0.0 0.0086 16.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 CCU99484.1 - 2e-05 23.8 1.2 0.0045 16.1 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 CCU99484.1 - 2.2e-05 23.4 4.7 0.00066 18.6 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.1 CCU99484.1 - 2.5e-05 24.4 0.0 0.031 14.5 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding GIDA PF01134.17 CCU99484.1 - 2.6e-05 23.2 2.5 0.037 12.8 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 CCU99484.1 - 4.3e-05 22.7 1.1 0.0084 15.2 0.1 2.2 2 0 0 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.16 CCU99484.1 - 7.8e-05 22.3 0.1 0.022 14.3 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 CCU99484.1 - 7.9e-05 21.2 2.6 0.066 11.6 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 CCU99484.1 - 0.00012 21.3 0.8 0.14 11.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase 3HCDH_N PF02737.13 CCU99484.1 - 0.0013 18.4 0.2 0.0013 18.4 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCU99484.1 - 0.0058 16.6 0.5 0.091 12.7 0.0 2.7 3 0 0 3 3 3 1 NADH(P)-binding ThiF PF00899.16 CCU99484.1 - 0.016 15.0 0.3 6.8 6.5 0.0 2.7 3 0 0 3 3 3 0 ThiF family 2-Hacid_dh_C PF02826.14 CCU99484.1 - 0.039 13.0 0.0 1.7 7.7 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CCU99484.1 - 0.042 13.2 0.1 0.077 12.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ldh_1_N PF00056.18 CCU99484.1 - 0.17 11.7 0.2 4.9 6.9 0.0 2.7 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Malic_M PF03949.10 CCU99484.1 - 0.19 11.2 0.2 2.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain TrkA_N PF02254.13 CCU99484.1 - 0.21 11.5 0.4 3 7.8 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Nol1_Nop2_Fmu PF01189.12 CCU99485.1 - 2.7e-91 305.8 0.0 3.9e-91 305.3 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 CCU99485.1 - 0.0021 18.0 0.2 0.0067 16.4 0.0 1.9 2 1 0 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.11 CCU99485.1 - 0.0033 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 CCU99485.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 CCU99485.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DNA_pol_B PF00136.16 CCU99486.1 - 2.4e-132 442.0 1.9 3.5e-132 441.4 1.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CCU99486.1 - 5.1e-56 189.8 0.0 1e-55 188.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.8 CCU99486.1 - 0.014 14.0 1.2 0.081 11.5 0.0 2.4 3 0 0 3 3 3 0 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 CCU99486.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CCU99486.1 - 0.026 14.3 0.2 0.34 10.6 0.0 2.9 3 1 0 3 3 3 0 RNase_H superfamily Lon_C PF05362.8 CCU99487.1 - 1e-64 217.6 0.1 2.2e-64 216.5 0.0 1.6 2 0 0 2 2 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CCU99487.1 - 3.8e-21 75.6 0.0 2.1e-20 73.2 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 CCU99487.1 - 9.7e-11 41.7 0.1 9.7e-11 41.7 0.1 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 CCU99487.1 - 3.5e-07 29.7 0.0 1.8e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 CCU99487.1 - 1.9e-06 27.6 0.0 3.9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CCU99487.1 - 1.7e-05 25.6 0.0 7.3e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 CCU99487.1 - 1.9e-05 23.5 0.2 3.9e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 PrkA AAA domain AAA_2 PF07724.9 CCU99487.1 - 2.2e-05 24.4 0.0 7e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCU99487.1 - 8.3e-05 22.6 0.1 0.00093 19.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 CCU99487.1 - 0.00016 20.5 0.3 0.021 13.5 0.1 2.3 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 CCU99487.1 - 0.00019 20.6 0.0 0.0036 16.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCU99487.1 - 0.00026 21.1 0.2 0.0087 16.1 0.1 2.7 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 CCU99487.1 - 0.00049 20.0 1.9 0.036 13.9 0.0 2.7 3 0 0 3 3 3 1 Shikimate kinase AAA_18 PF13238.1 CCU99487.1 - 0.00084 19.6 3.6 0.001 19.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CCU99487.1 - 0.0016 18.3 0.0 0.0044 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCU99487.1 - 0.02 14.8 0.3 4.5 7.2 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 CCU99487.1 - 0.027 14.0 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCU99487.1 - 0.028 13.6 0.0 0.065 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CCU99487.1 - 0.028 14.5 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 CCU99487.1 - 0.039 13.4 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 CCU99487.1 - 0.04 13.5 0.1 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 CCU99487.1 - 0.044 13.1 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 CCU99487.1 - 0.06 13.0 0.3 0.72 9.5 0.0 2.3 1 1 1 2 2 2 0 NTPase ClpB_D2-small PF10431.4 CCU99487.1 - 0.063 13.1 0.2 0.063 13.1 0.1 3.1 4 0 0 4 4 2 0 C-terminal, D2-small domain, of ClpB protein AAA_25 PF13481.1 CCU99487.1 - 0.074 12.4 0.1 0.2 11.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain Phage_connect_1 PF05135.8 CCU99487.1 - 0.11 12.6 0.2 0.53 10.4 0.1 2.1 1 1 0 1 1 1 0 Phage gp6-like head-tail connector protein AAA_33 PF13671.1 CCU99487.1 - 0.13 12.1 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_21 PF13304.1 CCU99487.1 - 0.17 11.8 1.1 1 9.2 0.0 2.6 2 1 1 3 3 3 0 AAA domain SMC_N PF02463.14 CCU99487.1 - 0.18 11.0 0.1 0.54 9.4 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCU99487.1 - 0.24 11.7 0.1 0.24 11.7 0.0 2.5 2 1 0 2 2 1 0 AAA domain ADK PF00406.17 CCU99487.1 - 0.62 9.9 4.5 13 5.6 0.7 3.1 3 0 0 3 3 3 0 Adenylate kinase ABC_tran PF00005.22 CCU99487.1 - 1.9 8.7 4.4 0.72 10.1 0.5 2.1 2 0 0 2 2 2 0 ABC transporter Ran_BP1 PF00638.13 CCU99489.1 - 2.5e-13 50.1 0.2 7e-13 48.6 0.2 1.7 1 1 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 CCU99489.1 - 0.0021 17.7 0.1 0.0069 16.0 0.1 1.7 1 1 0 1 1 1 1 WH1 domain Pro_isomerase PF00160.16 CCU99490.1 - 7.8e-39 133.3 0.0 1.6e-38 132.3 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD p450 PF00067.17 CCU99491.1 - 1.2e-59 202.0 0.2 7.7e-50 169.7 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 UDPGT PF00201.13 CCU99492.1 - 9.2e-10 37.6 0.1 5.1e-09 35.2 0.1 1.9 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase KH_1 PF00013.24 CCU99493.1 - 4.3e-40 135.1 9.0 1e-14 53.8 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCU99493.1 - 2.1e-29 100.6 16.4 2.4e-10 39.7 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CCU99493.1 - 1.9e-15 56.1 7.5 2.2e-06 27.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CCU99493.1 - 3e-07 29.9 3.5 0.39 10.3 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CCU99493.1 - 0.0061 16.3 6.1 1.3 8.9 0.1 3.7 3 1 0 3 3 3 2 NusA-like KH domain MIF4G PF02854.14 CCU99494.1 - 1.7e-38 132.1 0.0 1.3e-18 67.2 0.0 2.2 2 0 0 2 2 2 2 MIF4G domain Hexapep PF00132.19 CCU99495.1 - 1.4e-07 30.6 1.1 0.0021 17.5 0.2 3.4 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 CCU99495.1 - 0.00013 21.3 0.0 0.0029 16.9 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep_2 PF14602.1 CCU99495.1 - 0.0014 18.1 4.1 0.0022 17.5 1.6 2.2 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 CCU99495.1 - 0.0029 17.6 2.2 0.023 14.7 1.3 2.2 1 1 0 1 1 1 1 MobA-like NTP transferase domain CDP-OH_P_transf PF01066.16 CCU99496.1 - 7.9e-16 58.2 2.8 1.8e-15 57.0 2.0 1.6 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase OGFr_III PF04680.8 CCU99496.1 - 0.93 9.7 7.2 2.8 8.2 5.0 1.8 1 0 0 1 1 1 0 Opioid growth factor receptor repeat ABC_membrane PF00664.18 CCU99497.1 - 1.3e-45 155.9 4.3 1.7e-45 155.5 3.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CCU99497.1 - 1.7e-31 109.3 0.0 2.9e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_ATPase PF09818.4 CCU99497.1 - 1.8e-05 23.5 0.0 2.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.1 CCU99497.1 - 9.5e-05 22.4 0.1 0.00038 20.4 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 CCU99497.1 - 0.00016 20.8 0.0 0.00042 19.4 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin SMC_N PF02463.14 CCU99497.1 - 0.00073 18.8 0.1 0.032 13.4 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCU99497.1 - 0.0095 15.9 0.1 0.071 13.0 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCU99497.1 - 0.018 15.1 0.1 0.18 11.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 CCU99497.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 CCU99497.1 - 0.031 13.8 0.0 0.079 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CCU99497.1 - 0.18 11.2 0.6 9.1 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain EPSP_synthase PF00275.15 CCU99498.1 - 2.5e-126 421.5 0.0 4e-126 420.8 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CCU99498.1 - 4.5e-93 310.9 0.1 4.5e-93 310.9 0.0 2.0 3 0 0 3 3 3 1 3-dehydroquinate synthase DHquinase_I PF01487.10 CCU99498.1 - 3.4e-54 183.8 0.0 6.4e-54 182.9 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 CCU99498.1 - 8.5e-29 100.4 0.0 4.4e-27 94.8 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 CCU99498.1 - 5.9e-25 87.1 0.0 2e-24 85.4 0.0 2.0 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 CCU99498.1 - 2e-13 50.5 0.0 5.3e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 CCU99498.1 - 1.9e-05 24.1 0.0 6.3e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 CCU99498.1 - 0.00011 22.9 0.0 0.00034 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCU99498.1 - 0.016 15.1 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCU99498.1 - 0.086 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dus PF01207.12 CCU99499.1 - 3.8e-43 147.4 0.4 4.6e-42 143.9 0.1 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DUF1777 PF08648.7 CCU99499.1 - 1.2e-09 38.1 23.1 5.3e-09 36.0 16.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) HMGL-like PF00682.14 CCU99500.1 - 1.2e-71 241.1 0.5 2.1e-71 240.3 0.4 1.4 1 0 0 1 1 1 1 HMGL-like Transp_cyt_pur PF02133.10 CCU99501.1 - 2.6e-32 111.9 39.4 2.5e-31 108.7 27.3 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CLASP_N PF12348.3 CCU99502.1 - 5.8e-18 65.0 0.0 2.5e-06 27.0 0.0 4.8 5 0 0 5 5 5 3 CLASP N terminal HEAT PF02985.17 CCU99502.1 - 5.3e-12 44.7 27.3 0.0074 16.2 0.0 11.7 12 0 0 12 12 12 4 HEAT repeat Cohesin_HEAT PF12765.2 CCU99502.1 - 0.0027 17.6 0.7 1.3 9.0 0.0 3.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 CCU99502.1 - 0.004 15.5 2.1 4.4 5.5 0.0 4.0 4 0 0 4 4 4 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 CCU99502.1 - 0.008 14.5 0.1 0.008 14.5 0.0 2.7 4 0 0 4 4 4 1 Proteasome non-ATPase 26S subunit DUF2435 PF10363.4 CCU99502.1 - 0.032 14.1 0.9 21 5.1 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) VHS PF00790.14 CCU99502.1 - 0.039 13.6 0.4 1.2 8.7 0.0 3.0 3 0 0 3 3 3 0 VHS domain V-ATPase_H_C PF11698.3 CCU99502.1 - 0.32 10.9 0.0 48 3.9 0.0 3.2 3 0 0 3 3 3 0 V-ATPase subunit H PrkA PF06798.7 CCU99502.1 - 0.61 9.3 0.0 13 4.9 0.0 2.8 3 0 0 3 3 3 0 PrkA serine protein kinase C-terminal domain TAN PF11640.3 CCU99502.1 - 2 8.1 5.9 12 5.5 0.0 4.8 6 0 0 6 6 6 0 Telomere-length maintenance and DNA damage repair Cyto_heme_lyase PF01265.12 CCU99504.1 - 4.8e-64 216.4 0.2 6.4e-64 216.0 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Pkinase PF00069.20 CCU99504.1 - 2.7e-08 33.2 0.0 3.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99504.1 - 0.053 12.5 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kinase-like PF14531.1 CCU99504.1 - 0.079 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 CCU99505.1 - 1.2e-40 139.3 0.0 1.6e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99505.1 - 2.8e-27 95.4 0.0 3.7e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCU99505.1 - 0.0019 17.9 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CCU99505.1 - 0.0065 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 CCU99505.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 CCU99505.1 - 0.015 14.2 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 CCU99505.1 - 0.035 13.1 0.0 0.071 12.1 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Snf7 PF03357.16 CCU99506.1 - 2.2e-31 108.5 20.9 4.3e-31 107.5 14.5 1.4 1 1 0 1 1 1 1 Snf7 TPR_MLP1_2 PF07926.7 CCU99506.1 - 0.021 14.5 10.2 0.03 14.0 7.0 1.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Orthopox_A5L PF06193.6 CCU99506.1 - 0.023 14.6 0.5 0.023 14.6 0.4 2.0 1 1 1 2 2 2 0 Orthopoxvirus A5L protein-like DUF4396 PF14342.1 CCU99506.1 - 0.2 11.7 0.8 0.65 10.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) HTH_6 PF01418.12 CCU99506.1 - 0.33 10.7 2.8 0.2 11.4 0.3 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Peptidase_S46 PF10459.4 CCU99506.1 - 0.34 9.2 6.3 0.47 8.8 4.4 1.2 1 0 0 1 1 1 0 Peptidase S46 Lge1 PF11488.3 CCU99506.1 - 0.55 10.4 4.0 0.49 10.6 0.6 2.4 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Nsp1_C PF05064.8 CCU99506.1 - 0.74 9.4 5.2 0.49 10.0 0.8 2.4 1 1 2 3 3 3 0 Nsp1-like C-terminal region Allexi_40kDa PF05549.6 CCU99506.1 - 0.86 8.8 4.1 6 6.0 2.8 2.1 1 1 0 1 1 1 0 Allexivirus 40kDa protein Snapin_Pallidin PF14712.1 CCU99506.1 - 0.98 9.7 9.5 0.87 9.9 5.0 2.1 1 1 1 2 2 2 0 Snapin/Pallidin YlqD PF11068.3 CCU99506.1 - 1.2 9.1 13.7 1.1 9.3 6.4 2.1 1 1 1 2 2 2 0 YlqD protein COG2 PF06148.6 CCU99506.1 - 1.8 8.4 10.9 7.4 6.4 2.1 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIC PF04977.10 CCU99506.1 - 3.5 7.1 6.9 1.7 8.2 1.8 2.2 2 0 0 2 2 2 0 Septum formation initiator CLN3 PF02487.12 CCU99507.1 - 1.9e-49 168.5 2.9 2.3e-49 168.2 2.0 1.1 1 0 0 1 1 1 1 CLN3 protein ADK PF00406.17 CCU99508.1 - 1.1e-42 145.4 0.0 5e-42 143.3 0.0 1.8 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CCU99508.1 - 1.8e-10 41.1 0.0 4.9e-10 39.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 CCU99508.1 - 1.1e-07 32.6 0.0 1.8e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CCU99508.1 - 1.9e-07 30.6 0.1 0.00047 19.5 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 CCU99508.1 - 1.9e-06 27.7 0.0 0.002 17.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CCU99508.1 - 0.017 14.2 0.0 0.052 12.6 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin DUF1754 PF08555.5 CCU99509.1 - 4e-05 24.1 10.9 0.00021 21.8 4.6 2.4 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF4315 PF14193.1 CCU99509.1 - 0.057 13.3 0.7 0.1 12.5 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) ATP-synt_D PF01813.12 CCU99510.1 - 2.3e-40 138.2 2.0 1.1e-39 136.0 1.4 1.8 1 1 0 1 1 1 1 ATP synthase subunit D DUF1640 PF07798.6 CCU99510.1 - 0.012 15.7 0.9 0.018 15.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FH2 PF02181.18 CCU99511.1 - 1.2e-67 228.3 2.8 1.2e-67 228.3 1.9 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 CCU99511.1 - 1.5e-42 145.2 0.4 1.5e-42 145.2 0.3 2.5 2 1 2 4 4 4 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 CCU99511.1 - 1.1e-13 51.0 0.2 7.9e-06 25.3 0.0 3.1 2 1 1 3 3 3 2 Diaphanous GTPase-binding Domain Sec16_C PF12931.2 CCU99513.1 - 3.4e-64 217.3 0.0 4.1e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 TPR_14 PF13428.1 CCU99513.1 - 0.14 12.8 0.5 13 6.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.22 CCU99514.1 - 2.9e-34 118.3 0.0 9.1e-34 116.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 CCU99514.1 - 5.5e-08 32.3 0.0 0.00025 20.3 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCU99514.1 - 1.1e-06 28.8 0.0 0.0016 18.4 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA PF00004.24 CCU99514.1 - 5.1e-05 23.4 0.1 0.17 12.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCU99514.1 - 0.00011 22.2 0.1 0.00064 19.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CCU99514.1 - 0.00021 21.1 0.0 0.007 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCU99514.1 - 0.00083 19.0 0.0 0.0055 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CCU99514.1 - 0.0012 18.3 0.0 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCU99514.1 - 0.0013 18.8 0.2 0.015 15.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CCU99514.1 - 0.0034 16.5 0.0 0.0075 15.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 CCU99514.1 - 0.0088 15.5 0.0 0.015 14.8 0.0 1.4 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 CCU99514.1 - 0.012 15.5 0.2 0.077 12.9 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 CCU99514.1 - 0.027 15.3 0.1 0.06 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.10 CCU99514.1 - 0.035 12.7 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 CCU99514.1 - 0.076 12.9 0.0 0.23 11.4 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 CCU99514.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCU99514.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CCU99514.1 - 0.18 12.1 0.9 0.34 11.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain TP6A_N PF04406.9 CCU99515.1 - 5.3e-15 54.8 0.0 1.1e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Topoisom_bac PF01131.15 CCU99517.1 - 6.9e-87 291.8 0.3 9.1e-87 291.4 0.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 CCU99517.1 - 0.006 16.4 1.5 0.006 16.4 1.0 2.1 2 0 0 2 2 2 1 GRF zinc finger Cullin_Nedd8 PF10557.4 CCU99517.1 - 1.2 9.0 5.2 8.5 6.2 0.8 3.4 3 1 1 4 4 4 0 Cullin protein neddylation domain HAMP PF00672.20 CCU99518.1 - 8.8e-48 160.3 22.0 4.1e-08 33.2 0.1 8.8 8 1 1 9 9 9 7 HAMP domain HATPase_c PF02518.21 CCU99518.1 - 2.2e-26 91.7 0.0 9.4e-26 89.7 0.0 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CCU99518.1 - 4.2e-19 68.6 0.6 8.8e-16 57.9 0.2 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 CCU99518.1 - 2.4e-17 62.6 1.5 2e-16 59.6 0.3 3.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Pox_A_type_inc PF04508.7 CCU99518.1 - 4.3e-05 22.9 0.1 0.39 10.6 0.0 3.9 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat TMF_TATA_bd PF12325.3 CCU99518.1 - 0.008 15.9 1.7 2.9 7.6 0.0 4.0 3 0 0 3 3 3 1 TATA element modulatory factor 1 TATA binding VBS PF08913.5 CCU99518.1 - 0.24 11.6 9.5 11 6.3 0.1 5.0 4 1 0 4 4 4 0 Vinculin Binding Site Syntaxin PF00804.20 CCU99518.1 - 0.25 11.5 4.0 9.9 6.3 1.0 4.2 3 2 0 3 3 3 0 Syntaxin Ribosomal_S30AE PF02482.14 CCU99518.1 - 0.26 11.7 4.3 3.5e+02 1.7 0.0 5.9 6 1 1 7 7 7 0 Sigma 54 modulation protein / S30EA ribosomal protein TFIIS_M PF07500.9 CCU99519.1 - 2.4e-20 72.6 0.1 8.8e-20 70.8 0.0 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 CCU99519.1 - 1.2e-11 45.0 0.0 2.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 CCU99519.1 - 1.1e-10 40.9 10.5 1.9e-10 40.2 7.3 1.4 1 0 0 1 1 1 1 PHD-finger Nop14 PF04147.7 CCU99519.1 - 0.25 9.1 14.4 0.36 8.7 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family PAT1 PF09770.4 CCU99519.1 - 0.73 8.0 4.1 1.1 7.4 2.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GEMIN8 PF15348.1 CCU99519.1 - 2.8 7.9 9.1 0.44 10.5 1.3 2.3 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 PBP1_TM PF14812.1 CCU99519.1 - 3.6 7.9 20.0 4.9 7.5 5.7 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 CCU99519.1 - 8 6.0 16.8 1.8 8.1 5.2 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region MBOAT_2 PF13813.1 CCU99521.1 - 8.1e-10 38.6 5.0 9.1e-10 38.4 1.4 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MBOAT PF03062.14 CCU99521.1 - 3.8e-09 36.1 0.7 8.5e-09 34.9 0.5 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family WD40 PF00400.27 CCU99522.1 - 1.4e-07 31.0 0.0 2.4e-05 24.0 0.0 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Histone PF00125.19 CCU99523.1 - 7.4e-22 77.2 0.1 9.4e-22 76.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCU99523.1 - 0.044 13.8 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.20 CCU99524.1 - 2.9e-64 216.7 0.0 3.5e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99524.1 - 1.1e-41 142.6 0.0 1.4e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU99524.1 - 3.3e-08 32.8 0.0 4.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CCU99524.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CCU99524.1 - 0.019 14.7 0.1 0.049 13.3 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CCU99524.1 - 0.027 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CCU99524.1 - 0.23 10.2 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DUF814 PF05670.8 CCU99525.1 - 2.3e-20 72.2 0.1 1.2e-19 69.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF814) Sec62 PF03839.11 CCU99525.1 - 9.1 5.6 11.0 15 4.8 7.6 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Glycos_transf_2 PF00535.21 CCU99526.1 - 2.7e-19 69.4 0.0 5.7e-19 68.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CCU99526.1 - 1.7e-08 34.5 0.3 6.1e-05 22.9 0.0 3.0 2 1 1 3 3 3 2 Glycosyltransferase like family 2 SID-1_RNA_chan PF13965.1 CCU99526.1 - 0.099 10.7 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAH PF02671.16 CCU99527.1 - 1e-38 130.6 3.9 6.2e-18 64.1 1.2 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CCU99527.1 - 2.8e-37 126.5 0.1 6e-37 125.4 0.0 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor eIF-1a PF01176.14 CCU99528.1 - 9.9e-27 92.1 0.1 1.4e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 YIF1 PF03878.10 CCU99529.1 - 1.4e-72 243.7 4.1 1.1e-52 178.5 1.3 2.0 2 0 0 2 2 2 2 YIF1 Abhydrolase_9_N PF15420.1 CCU99529.1 - 0.67 9.6 8.0 4.7 6.8 0.2 2.6 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus RNA_pol_Rpb2_6 PF00562.23 CCU99530.1 - 4.6e-108 361.4 0.0 5.9e-108 361.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCU99530.1 - 2e-30 105.2 0.0 2.8e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 CCU99530.1 - 9.3e-24 82.9 0.0 2e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 CCU99530.1 - 2.2e-21 75.5 0.0 4.5e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 CCU99530.1 - 4.9e-21 74.9 0.0 7.3e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCU99530.1 - 5.5e-17 61.7 0.0 4.7e-16 58.8 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 CCU99530.1 - 0.027 14.4 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Nfu_N PF08712.6 CCU99531.1 - 9.4e-31 105.2 0.0 2.2e-30 104.1 0.0 1.6 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 CCU99531.1 - 7.3e-17 60.9 0.3 1.2e-16 60.2 0.2 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 CCU99531.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Peptidase_S10 PF00450.17 CCU99533.1 - 2.1e-91 307.1 0.0 2.4e-91 306.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase NOC3p PF07540.6 CCU99534.1 - 5.7e-23 81.0 0.0 1.7e-22 79.4 0.0 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 CCU99534.1 - 8.9e-15 54.5 1.7 1e-13 51.0 0.0 3.0 2 1 1 3 3 3 1 CBF/Mak21 family RRM_1 PF00076.17 CCU99535.1 - 1.8e-81 267.7 2.1 2e-20 72.1 0.3 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99535.1 - 8.7e-54 179.4 0.1 2.3e-13 49.9 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99535.1 - 7.2e-40 134.6 0.1 1.2e-09 37.8 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CCU99535.1 - 2.4e-30 103.9 1.5 2.9e-29 100.5 0.9 2.6 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 CCU99535.1 - 9.9e-05 22.0 1.6 8.5 6.2 0.0 4.4 3 1 1 4 4 4 1 Limkain b1 CbiG_mid PF11761.3 CCU99535.1 - 0.0017 18.5 0.1 2.9 8.1 0.0 3.1 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.1 CCU99535.1 - 0.0055 16.4 0.4 18 5.2 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif PNPase PF03726.9 CCU99535.1 - 2.4 8.4 5.3 7.1 6.9 0.2 3.2 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain GrpE PF01025.14 CCU99536.1 - 2.2e-44 150.9 0.3 2.8e-44 150.6 0.2 1.0 1 0 0 1 1 1 1 GrpE Mit_KHE1 PF10173.4 CCU99536.1 - 0.018 14.8 0.1 0.024 14.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF4201 PF13870.1 CCU99536.1 - 0.035 13.5 2.3 0.049 13.0 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.4 CCU99536.1 - 0.042 13.7 4.4 0.06 13.1 3.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cauli_DNA-bind PF03310.8 CCU99536.1 - 0.056 13.3 0.5 0.13 12.1 0.4 1.6 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein Microtub_assoc PF07989.6 CCU99536.1 - 0.57 10.0 4.2 0.94 9.3 2.4 1.7 1 1 1 2 2 2 0 Microtubule associated IncA PF04156.9 CCU99536.1 - 0.84 9.1 6.9 1.2 8.7 4.8 1.3 1 1 0 1 1 1 0 IncA protein TB2_DP1_HVA22 PF03134.14 CCU99537.1 - 2.6e-32 110.4 8.8 3.7e-32 109.9 6.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family KH_1 PF00013.24 CCU99538.1 - 7.8e-05 22.2 0.4 0.00018 21.0 0.3 1.6 1 0 0 1 1 1 1 KH domain MitMem_reg PF13012.1 CCU99539.1 - 2.4e-33 114.6 0.1 3.8e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CCU99539.1 - 5e-27 93.8 0.0 1.1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF663 PF04950.7 CCU99541.1 - 3.5e-77 259.2 0.0 6.5e-77 258.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CCU99541.1 - 2.6e-20 71.7 0.0 8e-20 70.1 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Nop14 PF04147.7 CCU99541.1 - 5.8 4.6 28.3 8.9 4.0 19.6 1.2 1 0 0 1 1 1 0 Nop14-like family ORMDL PF04061.9 CCU99542.1 - 2.3e-47 159.9 6.8 6.1e-47 158.5 4.7 1.6 1 1 0 1 1 1 1 ORMDL family LNS2 PF08235.8 CCU99544.1 - 3.1e-70 234.7 0.0 5.2e-70 234.0 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CCU99544.1 - 1.7e-27 95.2 0.1 3.9e-18 65.1 0.0 2.8 3 0 0 3 3 3 2 lipin, N-terminal conserved region AF1Q PF15017.1 CCU99544.1 - 0.014 15.3 2.3 0.016 15.1 0.1 2.1 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Med3 PF11593.3 CCU99544.1 - 0.049 12.8 2.4 0.086 12.0 1.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Acid_phosphat_B PF03767.9 CCU99544.1 - 0.1 11.9 0.0 0.74 9.1 0.0 2.0 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) KAT11 PF08214.6 CCU99545.1 - 7.1e-42 143.7 0.0 9.6e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein FKBP_C PF00254.23 CCU99546.1 - 8.7e-30 102.5 0.0 9.5e-30 102.4 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RCC1 PF00415.13 CCU99547.1 - 7.5e-53 176.5 8.0 7.2e-11 42.1 0.0 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCU99547.1 - 2.6e-36 122.4 32.2 1.2e-08 34.3 0.1 8.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat tRNA-synt_1 PF00133.17 CCU99549.1 - 2.4e-205 683.0 0.0 1e-204 681.0 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCU99549.1 - 4.1e-36 124.0 0.0 7.3e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCU99549.1 - 1.8e-16 59.8 0.1 3.5e-08 32.5 0.0 4.2 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CCU99549.1 - 2.5e-10 39.9 0.1 1.4e-06 27.7 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 CCU99549.1 - 0.00081 18.5 0.0 0.56 9.2 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 CCU99549.1 - 0.0024 16.7 0.0 0.041 12.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 CCU99549.1 - 0.13 11.3 0.0 0.97 8.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) IKI3 PF04762.7 CCU99550.1 - 1.7e-212 707.9 0.0 2.3e-212 707.4 0.0 1.1 1 0 0 1 1 1 1 IKI3 family MFS_1 PF07690.11 CCU99552.1 - 2.3e-41 141.7 27.5 2.3e-41 141.7 19.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCU99552.1 - 3.3e-12 45.7 22.9 9.3e-12 44.2 15.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter ECH PF00378.15 CCU99552.1 - 8.5e-07 28.3 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family OATP PF03137.15 CCU99552.1 - 0.049 11.6 4.7 0.21 9.6 3.2 2.0 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ABC1 PF03109.11 CCU99553.1 - 3.6e-29 101.1 0.1 6.7e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CCU99553.1 - 0.007 15.7 0.2 0.088 12.1 0.0 2.5 3 0 0 3 3 3 1 RIO1 family Pkinase PF00069.20 CCU99553.1 - 0.017 14.2 0.0 3.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain Spindle_Spc25 PF08234.7 CCU99554.1 - 1.4e-16 60.2 0.0 3.1e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Cortex-I_coil PF09304.5 CCU99554.1 - 1.8e-07 31.1 13.0 2.8e-07 30.5 9.0 1.3 1 0 0 1 1 1 1 Cortexillin I, coiled coil CALCOCO1 PF07888.6 CCU99554.1 - 0.0041 15.4 8.5 0.0051 15.1 5.9 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Striatin PF08232.7 CCU99554.1 - 0.042 14.1 11.1 0.065 13.5 7.7 1.2 1 0 0 1 1 1 0 Striatin family APG6 PF04111.7 CCU99554.1 - 0.045 12.8 9.7 0.061 12.3 6.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ERM PF00769.14 CCU99554.1 - 0.054 13.0 13.3 0.072 12.6 9.2 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Spc7 PF08317.6 CCU99554.1 - 0.16 10.5 7.3 0.13 10.9 3.9 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein CHASE3 PF05227.8 CCU99554.1 - 0.2 11.3 14.0 0.19 11.3 6.9 2.3 1 1 1 2 2 2 0 CHASE3 domain Jnk-SapK_ap_N PF09744.4 CCU99554.1 - 0.62 10.0 8.8 0.88 9.5 6.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.3 CCU99554.1 - 0.63 9.8 7.7 0.48 10.2 2.6 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 CCU99554.1 - 0.68 10.2 10.2 0.31 11.3 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Seryl_tRNA_N PF02403.17 CCU99554.1 - 0.88 9.6 9.3 0.65 10.0 2.9 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ax_dynein_light PF10211.4 CCU99554.1 - 0.94 9.2 12.3 0.37 10.5 2.2 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain GAS PF13851.1 CCU99554.1 - 1.1 8.4 8.9 0.59 9.2 4.7 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 CCU99554.1 - 1.1 7.0 3.1 1.3 6.8 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 CCU99554.1 - 1.5 7.6 8.9 2.3 7.0 6.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 CCU99554.1 - 1.7 8.1 8.0 1.9 8.0 2.1 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 CCU99554.1 - 1.9 8.8 7.5 5.5 7.3 4.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ING PF12998.2 CCU99554.1 - 2.3 8.5 8.3 3.3 8.0 0.2 2.5 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Fib_alpha PF08702.5 CCU99554.1 - 2.6 8.1 6.1 5.7 7.0 1.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 CCU99554.1 - 3.5 7.5 15.5 7.2 6.4 10.3 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding FlxA PF14282.1 CCU99554.1 - 5.3 7.0 10.0 5.1 7.0 4.7 2.2 1 1 0 1 1 1 0 FlxA-like protein HALZ PF02183.13 CCU99554.1 - 7.2 6.4 8.9 26 4.6 1.6 3.6 1 1 2 3 3 3 0 Homeobox associated leucine zipper Mnd1 PF03962.10 CCU99554.1 - 9.4 5.8 15.6 60 3.2 11.0 1.9 1 1 0 1 1 1 0 Mnd1 family Pkinase PF00069.20 CCU99555.1 - 4.1e-58 196.5 0.0 1.3e-57 194.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99555.1 - 3.4e-27 95.1 0.0 5e-19 68.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCU99555.1 - 4.3e-05 22.6 0.1 0.0027 16.7 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCU99555.1 - 0.0027 17.4 0.3 0.24 11.1 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family MAPEG PF01124.13 CCU99556.1 - 3.2e-22 78.4 7.1 3.7e-22 78.2 4.9 1.0 1 0 0 1 1 1 1 MAPEG family HECT PF00632.20 CCU99557.1 - 8e-97 324.1 0.0 1e-96 323.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-UBR PF02207.15 CCU99558.1 - 1.7e-13 50.0 17.2 1.7e-13 50.0 11.9 2.3 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CCU99558.1 - 3.2e-07 29.9 0.0 9.1e-07 28.5 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS TRAPP PF04051.11 CCU99559.1 - 9.6e-20 70.6 0.0 1.3e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Bromodomain PF00439.20 CCU99560.1 - 8.9e-36 121.6 0.1 1.7e-18 66.3 0.0 2.7 2 1 0 2 2 2 2 Bromodomain Striatin PF08232.7 CCU99560.1 - 9.3 6.5 9.7 3.8 7.8 2.4 3.2 2 1 1 3 3 3 0 Striatin family Abhydro_lipase PF04083.11 CCU99562.1 - 7.4e-14 50.8 0.0 1.7e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 CCU99562.1 - 5.1e-08 32.7 0.3 1.1e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCU99562.1 - 1.8e-05 24.7 0.6 1.8e-05 24.7 0.4 1.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCU99562.1 - 0.00011 21.9 0.0 0.00033 20.4 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family PUF PF00806.14 CCU99563.1 - 8.4e-65 210.7 11.2 1.2e-08 33.9 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RFC1 PF08519.7 CCU99564.1 - 1.7e-47 161.0 0.0 3.4e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 CCU99564.1 - 2e-08 34.2 0.0 3.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 CCU99564.1 - 9.3e-08 32.3 0.0 2.5e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CCU99564.1 - 2e-07 30.1 0.1 3.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CCU99564.1 - 0.00054 20.1 0.0 0.0018 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCU99564.1 - 0.00062 19.4 0.0 0.0018 18.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CCU99564.1 - 0.00066 19.5 0.0 0.0066 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCU99564.1 - 0.00082 20.1 0.5 0.0023 18.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 CCU99564.1 - 0.0063 16.3 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCU99564.1 - 0.016 15.1 4.9 0.018 15.0 0.1 3.0 2 1 2 4 4 4 0 AAA ATPase domain NTPase_1 PF03266.10 CCU99564.1 - 0.033 13.9 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 CCU99564.1 - 0.1 12.2 0.0 1.2 8.7 0.0 2.3 1 1 0 1 1 1 0 NACHT domain Rgp1 PF08737.5 CCU99565.1 - 3.4e-63 214.1 0.0 1.9e-34 119.4 0.0 2.4 1 1 1 2 2 2 2 Rgp1 Arrestin_C PF02752.17 CCU99565.1 - 0.0014 18.7 0.0 2.4 8.2 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCU99565.1 - 0.0034 17.2 0.0 0.0095 15.7 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Sec20 PF03908.8 CCU99566.1 - 1e-17 63.6 1.0 2e-17 62.6 0.7 1.5 1 0 0 1 1 1 1 Sec20 DUF1469 PF07332.6 CCU99566.1 - 0.034 13.8 1.7 0.062 13.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) adh_short PF00106.20 CCU99567.1 - 4.8e-20 72.1 0.4 7.6e-20 71.4 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCU99567.1 - 6.5e-08 32.6 0.2 9.5e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCU99567.1 - 1.5e-07 31.2 0.2 2.7e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 KR domain MmgE_PrpD PF03972.9 CCU99567.1 - 0.032 12.4 0.2 0.05 11.7 0.1 1.2 1 0 0 1 1 1 0 MmgE/PrpD family Arm PF00514.18 CCU99568.1 - 7.2e-69 225.4 28.0 1e-11 44.2 0.1 11.5 10 2 2 12 12 12 10 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CCU99568.1 - 2.9e-21 75.5 15.4 8.6e-06 25.9 0.0 7.3 2 2 3 6 6 6 5 HEAT repeats HEAT PF02985.17 CCU99568.1 - 1.1e-14 53.1 23.1 0.57 10.4 0.0 10.3 11 0 0 11 11 10 6 HEAT repeat HEAT_EZ PF13513.1 CCU99568.1 - 3.2e-14 52.9 17.4 0.13 12.8 0.2 9.0 8 3 2 10 10 8 5 HEAT-like repeat Adaptin_N PF01602.15 CCU99568.1 - 1.5e-10 40.0 8.5 2.7e-07 29.3 0.7 2.6 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 CCU99568.1 - 2e-09 36.9 7.2 6.2e-06 25.4 2.1 3.5 3 1 2 5 5 5 3 Armadillo-like KAP PF05804.7 CCU99568.1 - 5.6e-08 31.1 0.2 1.2e-07 30.1 0.1 1.4 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 CCU99568.1 - 7.3e-07 28.5 3.2 0.0039 16.3 0.3 4.3 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 CCU99568.1 - 0.014 15.3 1.7 26 4.7 0.0 3.8 2 1 2 4 4 4 0 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 CCU99568.1 - 0.049 14.0 0.1 5.1 7.5 0.0 2.8 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 CCU99568.1 - 0.21 12.1 12.8 18 6.1 0.1 7.5 9 0 0 9 9 7 0 PBS lyase HEAT-like repeat FF PF01846.14 CCU99569.1 - 2.3e-21 75.4 1.1 1e-06 28.5 0.0 5.9 5 1 0 5 5 5 4 FF domain WW PF00397.21 CCU99569.1 - 9.7 6.1 7.0 0.28 11.1 0.3 1.8 2 0 0 2 2 2 0 WW domain Abhydrolase_1 PF00561.15 CCU99570.1 - 5.1e-22 78.5 0.0 1.6e-20 73.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCU99570.1 - 0.0015 18.2 0.0 0.013 15.2 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 CCU99570.1 - 0.0034 17.2 0.0 0.0078 16.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein TIP120 PF08623.5 CCU99571.1 - 6.1e-35 120.2 0.1 6e-33 113.8 0.0 2.8 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 CCU99571.1 - 4.1e-05 23.7 8.3 0.00024 21.2 0.2 9.2 5 4 3 9 9 9 4 HEAT repeats HEAT PF02985.17 CCU99571.1 - 0.00044 20.1 43.2 0.00057 19.7 0.1 11.2 14 0 0 14 14 14 3 HEAT repeat Cnd1 PF12717.2 CCU99571.1 - 0.00092 19.1 3.5 1.9 8.3 0.0 5.2 4 2 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 CCU99571.1 - 0.002 16.5 10.5 1.9 6.7 0.0 5.0 5 1 0 5 5 5 3 Adaptin N terminal region DUF2435 PF10363.4 CCU99571.1 - 0.0025 17.6 2.4 6.9 6.6 0.1 5.1 5 0 0 5 5 5 1 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 CCU99571.1 - 0.0032 17.9 1.3 0.0032 17.9 0.9 13.5 14 2 3 17 17 17 3 HEAT-like repeat WD40 PF00400.27 CCU99572.1 - 0.0021 17.8 0.0 2.8 7.9 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat PQQ PF01011.16 CCU99572.1 - 0.022 14.2 0.0 0.37 10.4 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_2 PF13360.1 CCU99572.1 - 0.055 12.9 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain Lipase_3 PF01764.20 CCU99573.1 - 5e-27 94.2 0.0 7.1e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CCU99573.1 - 0.0072 15.7 0.0 0.016 14.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 CCU99573.1 - 0.0081 15.7 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCU99573.1 - 0.012 15.4 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCU99573.1 - 0.015 15.1 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 CCU99574.1 - 5.6e-19 68.0 25.9 7.1e-19 67.7 18.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 CCU99574.1 - 0.0055 16.7 7.8 0.026 14.5 1.3 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1228) LIP PF03583.9 CCU99575.1 - 2e-56 191.3 0.0 2.8e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 CCU99575.1 - 0.0025 17.7 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Branch_AA_trans PF05525.8 CCU99575.1 - 0.093 11.2 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport protein MFS_1 PF07690.11 CCU99576.1 - 1.5e-44 152.1 21.7 2e-44 151.7 15.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCU99576.1 - 3.2e-16 58.9 11.0 3.2e-16 58.9 7.6 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 CCU99576.1 - 0.00041 18.6 3.4 0.0006 18.1 2.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 CCU99576.1 - 0.00078 17.6 0.2 0.0057 14.7 0.1 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 CCU99576.1 - 0.002 16.3 5.9 0.0034 15.5 4.1 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector ESSS PF10183.4 CCU99576.1 - 0.094 13.1 0.1 0.094 13.1 0.0 2.1 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_2 PF13347.1 CCU99576.1 - 8.1 4.7 23.8 0.52 8.6 5.0 3.8 3 1 1 4 4 4 0 MFS/sugar transport protein MFS_1 PF07690.11 CCU99577.1 - 1.1e-52 178.8 25.2 4.1e-52 177.0 12.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCU99577.1 - 6.5e-14 51.3 25.2 1.7e-13 50.0 6.6 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 CCU99577.1 - 7.4e-07 27.7 2.3 1.2e-06 27.0 1.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 CCU99577.1 - 2.3e-06 25.9 1.9 2.9e-06 25.6 0.2 1.8 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 CCU99577.1 - 0.00078 17.6 1.2 0.00078 17.6 0.9 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector Peptidase_M3 PF01432.15 CCU99579.1 - 2e-125 419.4 0.0 2.5e-125 419.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 tRNA-synt_2d PF01409.15 CCU99580.1 - 1.6e-84 282.9 0.0 2.3e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CCU99580.1 - 0.00044 19.8 0.0 0.00093 18.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 CCU99580.1 - 0.0035 16.1 2.3 0.0039 16.0 0.0 2.1 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) WD40 PF00400.27 CCU99581.1 - 4.2e-55 181.7 11.4 4.9e-10 38.9 0.0 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 CCU99581.1 - 4.2e-10 38.6 4.4 8.8e-10 37.6 3.0 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nup160 PF11715.3 CCU99581.1 - 0.0052 14.9 0.9 0.17 9.9 0.1 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ribosomal_L24e PF01246.15 CCU99582.1 - 1.1e-31 108.4 3.5 2.5e-31 107.3 2.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e EFP_N PF08207.7 CCU99582.1 - 0.13 12.1 0.4 2.7 7.9 0.0 2.6 3 1 0 3 3 3 0 Elongation factor P (EF-P) KOW-like domain DUF2116 PF09889.4 CCU99582.1 - 2 8.2 4.5 4 7.3 0.7 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) SRP9-21 PF05486.7 CCU99583.1 - 2.7e-13 49.4 0.1 3.2e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) CTD_bind PF04818.8 CCU99584.1 - 0.03 14.5 0.0 0.36 11.0 0.0 2.3 3 0 0 3 3 3 0 RNA polymerase II-binding domain. PAT1 PF09770.4 CCU99584.1 - 5.3 5.1 8.4 5.7 5.0 5.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mus7 PF09462.5 CCU99585.1 - 3.9e-81 273.7 0.0 6e-81 273.1 0.0 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family RhoGEF PF00621.15 CCU99585.1 - 4.1e-36 124.5 0.4 2.1e-34 118.9 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 CCU99585.1 - 9.9e-17 60.6 10.4 1.9e-16 59.6 7.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 CCU99585.1 - 0.024 14.8 0.0 0.086 13.0 0.0 1.9 2 0 0 2 2 2 0 PH domain zf-RING_5 PF14634.1 CCU99585.1 - 0.097 12.4 10.0 0.21 11.3 7.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain IBR PF01485.16 CCU99585.1 - 0.14 12.0 2.0 0.33 10.8 1.4 1.5 1 0 0 1 1 1 0 IBR domain HypA PF01155.14 CCU99585.1 - 0.22 11.1 1.3 0.47 10.1 0.9 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C3HC4_2 PF13923.1 CCU99585.1 - 1.1 9.3 9.2 3.2 7.8 6.4 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCU99585.1 - 1.9 8.3 9.8 5.5 6.9 6.8 1.9 1 0 0 1 1 1 0 Ring finger domain FYVE_2 PF02318.11 CCU99585.1 - 3 7.7 5.2 6 6.7 3.6 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger FA_desaturase PF00487.19 CCU99586.1 - 2.5e-36 125.4 26.7 4.4e-36 124.6 18.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CCU99586.1 - 1.6e-11 43.7 0.0 1.1e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.27 CCU99587.1 - 3.9e-14 51.8 0.0 6.1e-06 25.9 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.1 CCU99587.1 - 0.028 14.6 1.1 88 3.5 0.0 4.0 3 0 0 3 3 3 0 PQQ-like domain PD40 PF07676.7 CCU99587.1 - 0.032 13.9 0.0 1 9.0 0.0 3.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat MMS1_N PF10433.4 CCU99587.1 - 0.054 11.6 0.0 1.7 6.6 0.0 2.1 1 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term AAA_19 PF13245.1 CCU99587.1 - 0.23 11.2 2.6 9.6 6.0 0.1 3.3 3 0 0 3 3 3 0 Part of AAA domain Myb_DNA-binding PF00249.26 CCU99588.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain XPA_C PF05181.7 CCU99589.1 - 4.7e-19 67.7 4.9 1.2e-17 63.1 3.4 2.8 1 1 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 CCU99589.1 - 0.012 15.3 0.8 0.081 12.6 0.1 2.4 2 0 0 2 2 2 0 XPA protein N-terminal FYVE PF01363.16 CCU99589.1 - 0.15 12.0 2.7 6.9 6.6 0.1 2.6 2 0 0 2 2 2 0 FYVE zinc finger SET PF00856.23 CCU99590.1 - 2.7e-23 83.0 3.9 9.1e-23 81.3 0.2 2.7 2 1 0 2 2 2 1 SET domain SRI PF08236.6 CCU99590.1 - 7.6e-16 57.8 0.7 2e-15 56.4 0.5 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Interferon PF00143.14 CCU99591.1 - 0.14 12.0 0.6 0.28 11.0 0.4 1.5 1 0 0 1 1 1 0 Interferon alpha/beta domain Sod_Fe_C PF02777.13 CCU99592.1 - 5.1e-35 119.5 0.4 8.9e-35 118.7 0.3 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CCU99592.1 - 9e-32 109.1 2.4 9.7e-32 109.0 0.6 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RNA_pol PF00940.14 CCU99593.1 - 2.3e-157 523.6 0.0 3.3e-157 523.1 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 CCU99593.1 - 9.5e-77 258.3 4.7 1.5e-76 257.7 3.3 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 CCU99593.1 - 0.00019 21.3 0.0 0.16 11.9 0.0 2.8 2 1 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 CCU99593.1 - 0.00026 21.0 0.3 0.15 12.4 0.0 3.4 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.15 CCU99593.1 - 0.0038 17.1 0.2 3.8 7.6 0.0 3.6 3 0 0 3 3 3 1 PPR repeat GMC_oxred_N PF00732.14 CCU99594.1 - 1.4e-38 132.7 0.4 1.9e-38 132.3 0.3 1.2 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCU99594.1 - 3.5e-09 36.0 7.5 5e-05 22.3 3.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCU99594.1 - 9.8e-09 34.5 6.7 8.6e-06 24.8 1.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 CCU99594.1 - 2.1e-05 24.4 0.4 4.2e-05 23.5 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCU99594.1 - 8.3e-05 21.7 0.1 0.00018 20.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 CCU99594.1 - 8.6e-05 21.7 1.2 0.00021 20.4 0.9 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CCU99594.1 - 0.00029 20.8 2.0 0.00029 20.8 1.4 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCU99594.1 - 0.0073 16.6 0.1 0.02 15.3 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCU99594.1 - 0.037 12.9 0.1 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 CCU99594.1 - 0.046 13.3 0.1 0.082 12.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 CCU99594.1 - 0.14 10.5 3.4 0.14 10.6 1.0 1.8 2 0 0 2 2 2 0 HI0933-like protein FliG_M PF14841.1 CCU99594.1 - 0.18 11.8 0.1 0.38 10.7 0.1 1.4 1 0 0 1 1 1 0 FliG middle domain UDPG_MGDP_dh_N PF03721.9 CCU99594.1 - 0.19 11.0 2.2 0.33 10.3 1.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 CCU99594.1 - 1 8.3 6.2 2.1 7.3 2.8 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase PMT PF02366.13 CCU99595.1 - 6.1e-69 232.0 12.6 1.2e-68 231.0 8.7 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCU99595.1 - 3.4e-16 59.3 3.4 3.8e-14 52.6 0.1 2.2 1 1 1 2 2 2 2 MIR domain Transposase_20 PF02371.11 CCU99595.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family Aldose_epim PF01263.15 CCU99596.1 - 2e-25 89.5 0.0 7.5e-25 87.6 0.0 1.9 1 1 0 1 1 1 1 Aldose 1-epimerase Kelch_3 PF13415.1 CCU99597.1 - 2.4e-14 53.0 5.8 0.00082 19.4 0.1 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CCU99597.1 - 6.7e-11 41.7 5.3 0.0012 18.5 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CCU99597.1 - 2.2e-10 40.2 1.0 3.3e-05 23.7 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CCU99597.1 - 0.00062 19.4 0.1 0.044 13.5 0.0 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 CCU99597.1 - 0.04 14.1 4.5 2.7 8.3 0.1 4.3 4 1 1 5 5 5 0 Kelch motif PAP1 PF08601.5 CCU99597.1 - 0.25 10.9 20.4 0.5 9.9 14.1 1.5 1 0 0 1 1 1 0 Transcription factor PAP1 DUF3074 PF11274.3 CCU99598.1 - 1.8e-39 135.2 0.0 2.6e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.14 CCU99598.1 - 0.051 12.8 0.0 8 5.7 0.0 2.2 2 0 0 2 2 2 0 START domain Adaptin_N PF01602.15 CCU99599.1 - 3.6e-146 487.5 3.6 4.3e-146 487.3 2.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCU99599.1 - 6.6e-26 91.2 1.9 5.2e-22 78.5 0.0 3.7 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CCU99599.1 - 2e-17 63.2 8.1 5.2e-09 36.2 0.1 5.4 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.17 CCU99599.1 - 9.4e-13 47.0 3.2 0.024 14.6 0.0 6.4 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.1 CCU99599.1 - 5.9e-06 26.5 5.4 0.063 13.7 0.1 6.3 5 1 2 7 7 7 1 HEAT-like repeat Cnd3 PF12719.2 CCU99599.1 - 9.6e-05 21.4 0.4 0.0023 16.9 0.1 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.3 CCU99599.1 - 0.00011 21.6 0.3 0.22 10.8 0.0 3.3 2 2 1 3 3 3 2 CLASP N terminal Cohesin_HEAT PF12765.2 CCU99599.1 - 0.073 13.0 2.2 9.7 6.2 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Sec7_N PF12783.2 CCU99599.1 - 0.074 12.4 0.2 0.3 10.5 0.0 2.1 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RrnaAD PF00398.15 CCU99600.1 - 2.1e-56 190.8 0.0 3e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CCU99600.1 - 1.2e-09 38.2 0.0 3.1e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCU99600.1 - 4.6e-07 30.3 0.0 8.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCU99600.1 - 2.9e-06 26.7 0.0 4.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CCU99600.1 - 1.5e-05 25.3 0.0 2.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCU99600.1 - 2.6e-05 24.6 0.0 4.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCU99600.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CCU99600.1 - 0.00061 19.3 0.0 0.00083 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 CCU99600.1 - 0.00066 19.4 0.0 0.0015 18.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 CCU99600.1 - 0.0019 17.4 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase NodS PF05401.6 CCU99600.1 - 0.0026 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.15 CCU99600.1 - 0.0047 16.0 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 CCU99600.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Ubie_methyltran PF01209.13 CCU99600.1 - 0.038 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Apc1 PF12859.2 CCU99601.1 - 2.8e-07 30.6 0.0 5.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 CCU99601.1 - 8.1e-06 25.7 22.6 0.0013 18.9 0.0 6.8 7 0 0 7 7 7 4 Proteasome/cyclosome repeat SPA PF08616.5 CCU99602.1 - 3.7e-22 78.1 0.0 6e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 CCU99602.1 - 1.4e-11 44.6 0.0 1.2e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2347 PF09804.4 CCU99602.1 - 0.0045 16.2 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 CCU99602.1 - 0.099 11.1 0.0 15 3.9 0.0 2.7 3 0 0 3 3 3 0 Transport protein Avl9 GCFC PF07842.7 CCU99604.1 - 1.9e-63 214.3 11.7 3.2e-63 213.6 8.1 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 CCU99604.1 - 3.6e-11 42.6 0.8 3.6e-11 42.6 0.6 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CCU99604.1 - 0.0002 21.1 0.7 0.0038 17.0 0.3 2.6 2 1 0 2 2 2 1 DExH-box splicing factor binding site Cyclin_N PF00134.18 CCU99605.1 - 9.1e-11 41.4 0.0 1.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 CCU99605.1 - 0.03 14.1 0.1 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Cyclin_C PF02984.14 CCU99605.1 - 0.12 12.2 2.0 4.1 7.3 0.0 2.8 2 1 0 2 2 2 0 Cyclin, C-terminal domain TPP_enzyme_N PF02776.13 CCU99606.1 - 1.9e-53 180.4 0.3 1e-52 178.0 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCU99606.1 - 4.8e-48 162.6 0.0 1.7e-46 157.5 0.0 2.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCU99606.1 - 2.2e-35 121.3 0.2 6.6e-35 119.8 0.2 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 CCU99606.1 - 0.025 14.1 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Ank_2 PF12796.2 CCU99608.1 - 3.7e-14 52.8 0.5 6.1e-14 52.1 0.4 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CCU99608.1 - 2.5e-11 42.7 0.6 5.2e-05 22.8 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CCU99608.1 - 5.4e-10 39.5 1.7 9.6e-05 22.7 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCU99608.1 - 6.5e-08 32.0 0.2 0.11 12.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CCU99608.1 - 8.9e-08 32.1 4.3 0.0017 18.5 0.2 3.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Nrap PF03813.9 CCU99609.1 - 1.5e-223 744.3 0.0 1.8e-223 744.1 0.0 1.0 1 0 0 1 1 1 1 Nrap protein DUF935 PF06074.7 CCU99609.1 - 0.017 13.8 0.2 0.017 13.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF935) Borrelia_lipo_1 PF05714.6 CCU99609.1 - 0.57 9.2 0.1 0.91 8.5 0.1 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein PI31_Prot_C PF08577.6 CCU99610.1 - 7.8e-10 39.2 8.4 1.7e-09 38.1 5.8 1.6 1 0 0 1 1 1 1 PI31 proteasome regulator PI31_Prot_N PF11566.3 CCU99610.1 - 0.0023 17.5 0.0 0.012 15.2 0.0 1.9 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal GPP34 PF05719.6 CCU99611.1 - 3.6e-58 197.0 0.9 4.7e-58 196.6 0.6 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) GRAM PF02893.15 CCU99612.1 - 7.3e-17 60.6 0.0 1.8e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 GRAM domain DEAD PF00270.24 CCU99613.1 - 1.5e-37 128.6 0.0 2.4e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU99613.1 - 1.6e-19 69.5 0.0 3.1e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CCU99613.1 - 3.9e-18 64.7 0.0 8.1e-18 63.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CCU99613.1 - 1.5e-06 28.1 0.1 5.7e-06 26.2 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4137 PF13593.1 CCU99613.1 - 0.081 12.0 0.1 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) Sporozoite_P67 PF05642.6 CCU99613.1 - 0.16 9.7 1.0 0.25 9.1 0.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pribosyltran_N PF13793.1 CCU99614.1 - 5.7e-36 122.7 0.2 3.3e-33 113.8 0.0 2.6 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CCU99614.1 - 5.7e-34 117.4 0.8 4.4e-33 114.5 0.5 2.0 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CCU99614.1 - 1e-15 57.5 0.1 1.3e-14 54.0 0.0 2.7 3 1 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCU99614.1 - 0.0044 16.2 0.0 0.0074 15.5 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PWI PF01480.12 CCU99615.1 - 1.8e-26 92.0 0.0 2.7e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 PWI domain Phage_term_smal PF05944.7 CCU99615.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Phage small terminase subunit WD40 PF00400.27 CCU99616.1 - 2.5e-64 211.0 14.4 8.6e-12 44.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CCU99616.1 - 8.8e-22 77.1 4.3 1.5e-21 76.3 3.0 1.4 1 0 0 1 1 1 1 Tup N-terminal PD40 PF07676.7 CCU99616.1 - 0.0088 15.6 0.1 29 4.4 0.0 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 CCU99616.1 - 0.009 15.1 0.1 1.9 7.5 0.0 3.3 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 CCU99616.1 - 0.037 13.3 1.1 1.9 7.8 0.0 3.0 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 CCU99616.1 - 0.042 12.1 0.0 0.33 9.1 0.0 1.8 1 1 0 1 1 1 0 Cytochrome D1 heme domain Spc7 PF08317.6 CCU99616.1 - 0.15 10.6 0.3 0.23 10.0 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_lysis PF03245.8 CCU99616.1 - 0.19 11.7 2.4 0.51 10.3 1.7 1.7 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein INCENP_ARK-bind PF03941.10 CCU99617.1 - 1.1e-08 34.7 0.4 4.5e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region PBP_sp32 PF07222.7 CCU99619.1 - 0.31 10.1 3.5 0.6 9.2 2.4 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SpaB_C PF14028.1 CCU99619.1 - 1.2 8.6 15.6 4.8 6.6 10.5 2.0 1 1 0 1 1 1 0 SpaB C-terminal domain Hydrolase_like2 PF13246.1 CCU99620.1 - 2e-13 50.0 0.0 6.8e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCU99620.1 - 4.5e-13 49.7 0.0 1.3e-12 48.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCU99620.1 - 3.7e-11 43.8 1.8 5.7e-06 26.9 0.6 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CCU99620.1 - 7.2e-10 38.2 0.0 2.8e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.7 CCU99620.1 - 0.00097 18.7 2.5 0.0061 16.1 0.1 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase His_Phos_1 PF00300.17 CCU99621.1 - 1.2e-06 28.7 0.0 5.2e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DinI PF06183.8 CCU99621.1 - 0.097 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 DinI-like family Acyl-CoA_dh_1 PF00441.19 CCU99622.1 - 3.7e-46 156.9 3.9 8.6e-46 155.7 2.7 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CCU99622.1 - 5.7e-26 91.3 0.5 1.3e-25 90.1 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CCU99622.1 - 5.3e-22 78.4 1.3 9.4e-22 77.7 0.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCU99622.1 - 3.6e-18 64.7 0.0 6.8e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Prefoldin_2 PF01920.15 CCU99622.1 - 0.026 14.2 0.1 2 8.1 0.0 2.6 2 0 0 2 2 2 0 Prefoldin subunit Tfb2 PF03849.9 CCU99623.1 - 1.5e-86 290.3 3.3 1.4e-82 277.2 2.3 2.2 1 1 0 1 1 1 1 Transcription factor Tfb2 SNF2_N PF00176.18 CCU99623.1 - 9.9e-41 139.4 0.1 9.3e-26 90.3 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Rad54_N PF08658.5 CCU99623.1 - 1.1e-38 132.9 1.2 2e-38 132.1 0.8 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C_3 PF13625.1 CCU99623.1 - 0.062 13.0 0.2 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Methyltransf_15 PF09445.5 CCU99625.1 - 1.3e-23 83.3 1.5 1.5e-17 63.6 0.0 3.0 1 1 1 2 2 2 2 RNA cap guanine-N2 methyltransferase Aminotran_1_2 PF00155.16 CCU99626.1 - 1.8e-40 139.0 0.0 2.1e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CCU99626.1 - 0.021 13.0 0.0 0.034 12.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme WD40 PF00400.27 CCU99627.1 - 1.1e-47 158.2 22.8 8.3e-11 41.3 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CCU99627.1 - 3.1e-29 101.8 0.0 8.6e-29 100.4 0.0 1.7 1 1 1 2 2 2 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 CCU99627.1 - 7.5e-05 21.0 2.3 0.22 9.5 0.1 3.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CCU99627.1 - 0.023 14.1 0.1 0.042 13.3 0.1 1.3 1 0 0 1 1 1 0 PQQ-like domain LisH PF08513.6 CCU99627.1 - 0.17 11.6 0.1 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 LisH Aldo_ket_red PF00248.16 CCU99628.1 - 8.7e-57 192.0 0.0 1.1e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_11 PF13414.1 CCU99629.1 - 5.9e-11 41.8 2.1 6.2e-07 28.9 0.1 4.1 4 1 1 5 5 5 2 TPR repeat TPR_17 PF13431.1 CCU99629.1 - 2.6e-06 27.1 0.5 0.21 11.9 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCU99629.1 - 2.2e-05 24.0 6.4 0.00027 20.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCU99629.1 - 3.8e-05 23.5 10.7 0.00084 19.2 0.1 5.5 4 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCU99629.1 - 0.00014 21.3 0.0 0.16 11.6 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCU99629.1 - 0.0036 16.9 0.1 0.25 11.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCU99629.1 - 0.077 13.6 0.1 0.077 13.6 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Paf67 PF10255.4 CCU99629.1 - 0.15 10.9 0.0 0.56 9.0 0.0 1.9 3 0 0 3 3 3 0 RNA polymerase I-associated factor PAF67 TPR_7 PF13176.1 CCU99629.1 - 4 7.4 7.5 60 3.8 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat LRR_6 PF13516.1 CCU99630.1 - 1.2e-16 58.7 0.2 1.1 9.5 0.0 8.9 11 0 0 11 11 11 4 Leucine Rich repeat LRR_1 PF00560.28 CCU99630.1 - 1.7e-14 51.6 2.3 6.2 7.2 0.1 10.0 10 1 0 10 10 10 4 Leucine Rich Repeat F-box-like PF12937.2 CCU99630.1 - 1.3e-12 47.1 3.0 1.3e-12 47.1 2.1 2.3 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 CCU99630.1 - 6.5e-12 45.0 1.4 0.44 10.3 0.0 6.5 4 2 2 6 6 6 3 Leucine rich repeat LRR_4 PF12799.2 CCU99630.1 - 2.6e-09 36.4 0.0 9.4 5.9 0.0 6.6 4 2 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CCU99630.1 - 2.9e-08 32.6 10.1 13 6.4 0.1 9.0 9 0 0 9 9 9 1 Leucine rich repeat F-box PF00646.28 CCU99630.1 - 0.003 17.1 2.9 0.005 16.4 0.1 2.9 3 0 0 3 3 3 1 F-box domain Ste50p-SAM PF09235.5 CCU99630.1 - 0.0052 16.7 7.1 14 5.8 0.0 5.2 3 1 2 5 5 5 1 Ste50p, sterile alpha motif F-box-like_2 PF13013.1 CCU99630.1 - 0.01 15.5 0.3 0.01 15.5 0.2 2.1 3 0 0 3 3 3 1 F-box-like domain DUF3558 PF12079.3 CCU99630.1 - 0.14 11.7 4.0 1.7 8.3 0.4 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3558) Coatomer_WDAD PF04053.9 CCU99631.1 - 5e-136 454.0 0.0 1.2e-135 452.7 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 CCU99631.1 - 1.6e-51 170.3 9.7 9.4e-11 41.1 0.3 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 CCU99631.1 - 0.12 10.4 2.0 1.3 7.1 0.0 3.5 3 1 2 5 5 5 0 Nucleoporin Nup120/160 Myb_DNA-binding PF00249.26 CCU99632.1 - 8.5e-12 44.9 0.9 2.4e-11 43.5 0.6 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCU99632.1 - 2.8e-07 30.5 1.7 3.5e-07 30.2 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF202 PF02656.10 CCU99633.1 - 8e-12 45.2 7.0 8e-12 45.2 4.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4131 PF13567.1 CCU99633.1 - 8 5.8 7.1 15 4.9 4.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Pro_isomerase PF00160.16 CCU99634.1 - 3.8e-32 111.6 0.0 5.5e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2435 PF10363.4 CCU99635.1 - 2.8e-26 91.2 0.1 1e-25 89.4 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 CCU99635.1 - 1.3e-05 24.5 1.0 1.3e-05 24.5 0.7 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF2411) Palm_thioest PF02089.10 CCU99637.1 - 1.1e-53 182.0 0.0 1.4e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 CCU99637.1 - 0.032 13.8 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold MBOAT PF03062.14 CCU99638.1 - 4.6e-46 157.4 7.4 4.6e-46 157.4 5.1 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Phage_30_3 PF08010.6 CCU99638.1 - 0.068 12.6 0.2 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage protein GP30.3 Pox_A14 PF05767.7 CCU99638.1 - 0.1 12.5 0.4 1.5 8.8 0.0 3.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF3815 PF12821.2 CCU99638.1 - 0.66 9.9 7.7 0.22 11.4 0.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3815) WD40 PF00400.27 CCU99639.1 - 2.6e-48 160.2 16.4 1.3e-08 34.3 0.0 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat Vps5 PF09325.5 CCU99639.1 - 5e-17 61.9 4.9 9.1e-17 61.0 3.4 1.4 1 0 0 1 1 1 1 Vps5 C terminal like ISG65-75 PF11727.3 CCU99639.1 - 0.12 11.4 0.8 0.27 10.2 0.5 1.6 1 0 0 1 1 1 0 Invariant surface glycoprotein GTP_EFTU PF00009.22 CCU99640.1 - 2.8e-50 170.3 0.0 4.2e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CCU99640.1 - 2.1e-08 33.8 0.0 6.5e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.13 CCU99640.1 - 1.8e-06 27.4 0.0 5.2e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 CCU99640.1 - 4.3e-06 26.7 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCU99640.1 - 0.00011 22.0 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 CCU99640.1 - 0.085 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Ras family Dynamin_N PF00350.18 CCU99640.1 - 0.16 11.7 0.1 1.5 8.6 0.1 2.2 1 1 0 1 1 1 0 Dynamin family Miro PF08477.8 CCU99640.1 - 0.22 12.0 0.0 0.45 11.0 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein ADH_zinc_N_2 PF13602.1 CCU99641.1 - 2.6e-09 38.0 0.0 6.7e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCU99641.1 - 0.00012 21.8 0.1 0.00023 20.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCU99641.1 - 0.0025 17.3 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LRR_4 PF12799.2 CCU99642.1 - 1.5e-11 43.6 0.3 0.00016 21.1 0.0 4.4 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCU99642.1 - 7.5e-09 35.2 2.2 1.3e-06 28.0 0.3 3.1 1 1 2 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 CCU99642.1 - 6.3e-05 22.5 5.6 6.9 7.3 0.1 5.0 5 0 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 CCU99642.1 - 9.9e-05 21.8 0.6 3.1 8.1 0.0 4.6 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.1 CCU99642.1 - 0.00065 19.5 3.6 2.9 8.2 0.1 4.3 4 1 1 5 5 5 2 Leucine Rich repeat CAP_GLY PF01302.20 CCU99642.1 - 0.00091 18.8 0.1 0.0021 17.7 0.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain LRR_9 PF14580.1 CCU99642.1 - 0.001 18.6 0.0 1.6 8.2 0.0 2.6 1 1 0 2 2 2 2 Leucine-rich repeat RRM_1 PF00076.17 CCU99643.1 - 1e-08 34.6 0.0 0.0013 18.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99643.1 - 1.5e-05 24.8 0.0 0.0069 16.3 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99643.1 - 3.9e-05 23.4 0.0 0.0055 16.5 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_6 PF12697.2 CCU99643.1 - 7.7e-05 22.6 1.7 7.7e-05 22.6 1.2 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CCU99643.1 - 9.3e-05 22.1 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CCU99643.1 - 0.0013 18.5 0.1 0.0029 17.3 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CCU99643.1 - 0.0054 16.9 0.1 0.099 12.8 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain Lipase_3 PF01764.20 CCU99643.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.9 CCU99643.1 - 0.22 10.7 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.10 CCU99643.1 - 0.27 10.1 0.0 0.42 9.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ribosomal_L7Ae PF01248.21 CCU99644.1 - 1e-28 98.6 1.4 1.3e-28 98.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_S17 PF00366.15 CCU99645.1 - 1.6e-27 95.3 1.5 2.3e-27 94.8 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L1 PF00687.16 CCU99646.1 - 6.9e-51 172.6 3.7 8.5e-51 172.4 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Borealin PF10512.4 CCU99646.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 TCTP PF00838.12 CCU99649.1 - 2.2e-67 226.1 2.2 2.5e-67 226.0 1.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein TroA PF01297.12 CCU99649.1 - 0.023 13.9 0.1 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Periplasmic solute binding protein family L31 PF09784.4 CCU99649.1 - 0.15 12.1 0.4 0.73 9.9 0.3 1.9 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 RRM_1 PF00076.17 CCU99650.1 - 5.2e-18 64.4 0.0 7.8e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99650.1 - 5.9e-11 42.1 0.0 1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99650.1 - 0.002 17.9 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTNNBL PF08216.6 CCU99651.1 - 1.5e-23 82.4 0.2 3.9e-23 81.0 0.0 1.9 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear E3_UbLigase_R4 PF13764.1 CCU99651.1 - 0.024 12.5 0.8 0.082 10.7 0.1 1.8 1 1 0 2 2 2 0 E3 ubiquitin-protein ligase UBR4 Vac14_Fab1_bd PF12755.2 CCU99652.1 - 3.2e-43 146.0 0.2 1.7e-38 130.8 0.0 4.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.3 CCU99652.1 - 1.8e-23 82.5 2.3 2.7e-23 82.0 0.8 1.9 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.17 CCU99652.1 - 5e-16 57.2 7.3 0.0012 18.7 0.0 7.8 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 CCU99652.1 - 1.2e-10 41.5 0.4 0.0067 16.6 0.0 5.1 2 2 3 5 5 5 4 HEAT repeats CLASP_N PF12348.3 CCU99652.1 - 5e-05 22.7 2.1 1.9 7.7 0.0 4.9 5 1 1 6 6 6 2 CLASP N terminal MMS19_C PF12460.3 CCU99652.1 - 0.0016 17.2 6.0 0.013 14.2 0.0 3.6 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal ParcG PF10274.4 CCU99652.1 - 0.0061 16.4 0.1 0.27 11.1 0.0 2.9 3 0 0 3 3 3 1 Parkin co-regulated protein HEAT_EZ PF13513.1 CCU99652.1 - 0.021 15.2 6.1 17 6.0 0.0 5.1 6 0 0 6 6 6 0 HEAT-like repeat UCH PF00443.24 CCU99653.1 - 2.4e-51 174.4 0.0 2.9e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCU99653.1 - 4.5e-19 69.0 0.0 6.2e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 CCU99653.1 - 0.00036 19.9 0.0 0.86 8.8 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Cyanate_lyase PF02560.9 CCU99653.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 Cyanate lyase C-terminal domain Peptidase_C14 PF00656.17 CCU99654.1 - 7.5e-62 209.2 0.0 8.7e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Caspase domain PH PF00169.24 CCU99655.1 - 2.7e-13 50.0 0.0 4.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 CCU99655.1 - 9.3e-13 47.5 0.1 1.6e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCU99655.1 - 4.9e-12 45.0 0.1 1e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 CCU99655.1 - 3.9e-08 33.0 0.0 5.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 CCU99655.1 - 1.1e-07 31.1 0.0 2.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 CCU99655.1 - 0.0011 19.0 0.1 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 CCU99655.1 - 0.0029 17.3 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain PH_11 PF15413.1 CCU99655.1 - 0.11 12.8 0.1 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain DnaJ PF00226.26 CCU99656.1 - 4.3e-20 71.2 5.0 9.5e-20 70.1 0.5 2.7 3 0 0 3 3 3 1 DnaJ domain NOB1_Zn_bind PF08772.6 CCU99657.1 - 3.6e-26 90.7 0.1 6.9e-26 89.8 0.0 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Ribosomal_60s PF00428.14 CCU99657.1 - 0.051 13.9 4.1 0.51 10.7 1.4 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-ribbon_3 PF13248.1 CCU99657.1 - 0.062 12.5 5.1 0.11 11.7 3.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain AF1Q PF15017.1 CCU99657.1 - 0.44 10.4 7.7 1 9.3 3.6 2.6 2 1 0 2 2 2 0 Drug resistance and apoptosis regulator Cofilin_ADF PF00241.15 CCU99659.1 - 3.1e-08 33.5 0.0 3.4e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ox_reductase_C PF08635.5 CCU99660.1 - 5.4e-71 236.5 0.0 7.4e-71 236.1 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 CCU99660.1 - 6.3e-23 81.5 0.0 1.2e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Clathrin_lg_ch PF01086.12 CCU99662.1 - 1.5e-29 103.5 15.8 3.6e-23 82.6 11.0 3.3 1 1 0 1 1 1 1 Clathrin light chain FadA PF09403.5 CCU99662.1 - 0.41 10.6 7.5 1 9.3 5.2 1.6 1 0 0 1 1 1 0 Adhesion protein FadA V-ATPase_G PF03179.10 CCU99662.1 - 1.9 8.8 14.1 3.4 8.0 9.8 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit YdfA_immunity PF12127.3 CCU99662.1 - 2.9 6.6 4.9 4.2 6.1 3.4 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial Ribosomal_L13 PF00572.13 CCU99663.1 - 6e-49 165.3 0.1 7e-49 165.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 SMC_N PF02463.14 CCU99664.1 - 7.7e-14 51.4 0.0 1.5e-13 50.4 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCU99664.1 - 3.1e-08 34.1 18.1 9.9e-08 32.5 0.2 5.2 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.1 CCU99664.1 - 5.8e-05 23.1 0.0 0.0043 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain ADIP PF11559.3 CCU99664.1 - 0.0016 18.3 11.0 0.0016 18.3 7.6 6.8 5 1 2 7 7 7 2 Afadin- and alpha -actinin-Binding DivIC PF04977.10 CCU99664.1 - 0.013 14.9 0.1 0.013 14.9 0.1 8.1 7 3 2 9 9 9 0 Septum formation initiator AAA_29 PF13555.1 CCU99664.1 - 0.024 14.1 0.1 0.052 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2205 PF10224.4 CCU99664.1 - 0.034 13.7 0.2 0.034 13.7 0.1 6.1 6 1 1 7 7 7 0 Predicted coiled-coil protein (DUF2205) AAA_19 PF13245.1 CCU99664.1 - 0.049 13.3 0.2 0.33 10.7 0.1 2.5 1 0 0 1 1 1 0 Part of AAA domain MTBP_N PF14918.1 CCU99664.1 - 0.05 12.9 3.4 0.088 12.2 0.4 2.2 2 0 0 2 2 2 0 MDM2-binding AAA_13 PF13166.1 CCU99664.1 - 0.15 10.5 27.6 0.0094 14.4 1.2 4.3 3 1 1 4 4 4 0 AAA domain ABC_tran PF00005.22 CCU99664.1 - 0.15 12.3 0.0 0.15 12.3 0.0 4.5 4 1 0 4 4 4 0 ABC transporter AAA_17 PF13207.1 CCU99664.1 - 0.35 11.6 5.4 0.13 13.0 0.3 3.2 2 2 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CCU99664.1 - 1 9.5 0.0 1 9.5 0.0 3.7 3 1 0 3 3 3 0 AAA domain AAA PF00004.24 CCU99664.1 - 1.1 9.5 3.2 1.4 9.1 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) FlgM PF04316.8 CCU99664.1 - 4 7.4 23.0 0.063 13.2 0.3 4.4 4 1 0 4 4 4 0 Anti-sigma-28 factor, FlgM Cornichon PF03311.9 CCU99665.1 - 7.1e-46 155.5 14.7 1.4e-45 154.5 10.2 1.4 1 1 0 1 1 1 1 Cornichon protein MpPF26 PF07666.6 CCU99665.1 - 0.066 13.1 7.7 1.8 8.4 2.4 2.3 2 1 0 2 2 2 0 M penetrans paralogue family 26 DUF1634 PF07843.6 CCU99665.1 - 0.12 12.0 0.2 0.12 12.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) CBFD_NFYB_HMF PF00808.18 CCU99666.1 - 7e-25 86.8 0.0 1.3e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCU99666.1 - 0.00012 22.1 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ABC_tran PF00005.22 CCU99667.1 - 8.6e-46 155.6 0.1 6.2e-22 78.3 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 CCU99667.1 - 4.1e-20 71.4 1.9 4.1e-20 71.4 1.3 2.6 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 CCU99667.1 - 2.1e-19 70.5 1.4 0.00051 20.1 0.0 4.5 3 1 1 4 4 4 4 AAA domain AAA_23 PF13476.1 CCU99667.1 - 1.4e-09 38.5 6.3 0.0028 17.9 0.3 3.7 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 CCU99667.1 - 4e-09 36.0 1.3 0.52 9.5 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCU99667.1 - 9e-09 34.7 0.3 0.0025 17.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CCU99667.1 - 3.8e-08 34.1 0.9 0.0071 17.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCU99667.1 - 3.1e-07 29.7 0.0 0.00012 21.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCU99667.1 - 1.6e-06 28.2 0.5 0.016 15.3 0.0 3.5 2 2 0 2 2 2 2 AAA domain Miro PF08477.8 CCU99667.1 - 1.8e-06 28.4 0.0 0.13 12.8 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 CCU99667.1 - 2.8e-06 27.6 1.7 0.13 12.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.18 CCU99667.1 - 5.6e-06 26.2 0.2 0.0095 15.8 0.3 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.1 CCU99667.1 - 1e-05 24.7 12.8 0.085 11.8 0.0 4.9 4 1 1 5 5 5 2 AAA ATPase domain AAA_16 PF13191.1 CCU99667.1 - 1.6e-05 25.0 0.2 0.19 11.6 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 CCU99667.1 - 2.1e-05 24.2 0.2 0.2 11.3 0.0 2.5 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 CCU99667.1 - 2.5e-05 24.0 1.8 0.27 10.9 0.1 3.6 2 1 1 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CCU99667.1 - 3e-05 24.0 0.0 0.3 11.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 CCU99667.1 - 5.7e-05 23.0 4.8 0.12 12.2 0.1 3.7 2 1 1 3 3 3 2 Dynamin family AAA PF00004.24 CCU99667.1 - 9.1e-05 22.6 0.2 1.4 9.0 0.0 3.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 CCU99667.1 - 0.00013 21.4 0.0 0.56 9.6 0.0 2.7 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 CCU99667.1 - 0.00027 20.3 0.0 0.45 9.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CCU99667.1 - 0.00027 20.8 0.1 0.35 10.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 CCU99667.1 - 0.00049 19.6 0.1 0.3 10.4 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain FeoB_N PF02421.13 CCU99667.1 - 0.00062 19.0 0.1 0.04 13.1 0.1 2.7 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF87 PF01935.12 CCU99667.1 - 0.00075 19.3 4.7 0.98 9.1 0.0 4.2 3 1 1 4 4 4 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 CCU99667.1 - 0.0013 18.8 0.8 2.7 8.2 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_14 PF13173.1 CCU99667.1 - 0.0015 18.3 0.1 8.4 6.3 0.0 3.9 4 0 0 4 4 4 0 AAA domain cobW PF02492.14 CCU99667.1 - 0.0034 16.8 0.5 0.67 9.3 0.0 2.8 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 CCU99667.1 - 0.0051 16.4 0.8 1.4 8.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 CCU99667.1 - 0.006 15.4 0.0 3.2 6.5 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain SbcCD_C PF13558.1 CCU99667.1 - 0.0086 15.9 0.0 0.58 10.1 0.0 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 CCU99667.1 - 0.0088 15.7 0.4 3.7 7.2 0.1 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.7 CCU99667.1 - 0.011 15.0 1.9 1.6 7.9 0.0 3.2 3 1 1 4 4 4 0 Poxvirus A32 protein AAA_19 PF13245.1 CCU99667.1 - 0.012 15.2 0.1 1.9 8.2 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 CCU99667.1 - 0.022 13.6 0.8 3.4 6.4 0.0 2.5 2 1 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 CCU99667.1 - 0.027 13.9 0.8 5.6 6.4 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 CCU99667.1 - 0.028 13.9 0.7 2.2 7.7 0.0 2.9 3 1 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ArgK PF03308.11 CCU99667.1 - 0.034 12.9 0.0 8.6 5.0 0.0 2.6 2 0 0 2 2 2 0 ArgK protein Sigma54_activat PF00158.21 CCU99667.1 - 0.058 12.8 0.0 4.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 CCU99667.1 - 0.16 11.7 4.5 4.9 6.8 0.1 3.7 4 0 0 4 4 3 0 NTPase DUF2894 PF11445.3 CCU99667.1 - 0.32 11.2 3.9 10 6.2 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Septin PF00735.13 CCU99667.1 - 0.33 9.9 6.9 2.9 6.8 0.0 2.9 4 0 0 4 4 3 0 Septin MRP-L27 PF09809.4 CCU99668.1 - 0.00015 21.3 0.1 0.00029 20.4 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 LRR_4 PF12799.2 CCU99669.1 - 1.2e-05 24.7 0.2 6.7e-05 22.4 0.0 2.0 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCU99669.1 - 1.9e-05 24.3 0.4 6.2e-05 22.6 0.1 1.7 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 CCU99669.1 - 0.00029 20.4 1.1 2.6 8.3 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.1 CCU99669.1 - 0.0013 18.5 0.5 2.2 8.5 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich repeat LRR_7 PF13504.1 CCU99669.1 - 0.0013 18.5 0.5 0.72 10.2 0.0 3.1 3 0 0 3 3 3 1 Leucine rich repeat UDPGP PF01704.13 CCU99670.1 - 3e-183 609.1 0.3 3.5e-183 608.8 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Mito_carr PF00153.22 CCU99671.1 - 1.3e-45 153.0 4.7 4.6e-17 61.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MDM31_MDM32 PF08118.6 CCU99672.1 - 2.2e-97 326.6 2.2 4.7e-44 150.7 0.0 3.1 3 0 0 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins DUF2416 PF10315.4 CCU99673.1 - 9.9e-10 38.6 0.2 1.1e-09 38.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) EmrE PF13536.1 CCU99673.1 - 0.14 12.4 0.9 1.3 9.2 0.1 2.1 1 1 1 2 2 2 0 Multidrug resistance efflux transporter Snf7 PF03357.16 CCU99674.1 - 1.1e-15 57.4 14.9 2e-15 56.5 10.3 1.5 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.9 CCU99674.1 - 0.0029 17.0 3.0 0.0047 16.3 2.1 1.3 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway SYCE1 PF15233.1 CCU99674.1 - 0.12 12.3 4.3 0.36 10.7 2.5 2.0 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 Chitin_synth_2 PF03142.10 CCU99676.1 - 3.2e-235 781.5 0.0 5.3e-235 780.8 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CCU99676.1 - 1.1e-65 221.9 0.0 1.6e-62 211.5 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) Cyt-b5 PF00173.23 CCU99676.1 - 3.8e-19 68.2 0.0 2.3e-12 46.5 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 CCU99676.1 - 2.7e-15 56.8 0.0 4.6e-12 46.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CCU99676.1 - 3.7e-14 52.8 3.7 3.7e-14 52.8 2.5 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 CCU99676.1 - 1.2e-09 37.8 0.0 1.4e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.21 CCU99676.1 - 1e-07 31.8 0.0 0.0003 20.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CCU99676.1 - 0.00039 19.7 0.0 0.00083 18.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Thioredoxin_6 PF13848.1 CCU99676.1 - 0.081 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain BPL_LplA_LipB PF03099.14 CCU99677.1 - 2.8e-16 59.6 0.0 4.3e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Cnd3 PF12719.2 CCU99678.1 - 3.3e-77 259.4 7.7 3.9e-75 252.6 1.5 3.4 2 1 2 4 4 4 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 CCU99678.1 - 1.2e-12 47.8 22.7 1.9e-09 37.6 1.1 6.3 5 1 0 6 6 6 3 HEAT repeats HEAT PF02985.17 CCU99678.1 - 1.8e-10 39.9 13.6 0.23 11.6 0.1 7.3 7 0 0 7 7 7 4 HEAT repeat Adaptin_N PF01602.15 CCU99678.1 - 0.0066 14.8 0.2 0.25 9.6 0.1 3.0 3 1 1 4 4 4 1 Adaptin N terminal region Cnd1 PF12717.2 CCU99678.1 - 0.0097 15.7 5.1 0.31 10.8 1.6 4.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 CCU99678.1 - 0.01 15.2 0.1 0.22 10.8 0.0 2.8 3 0 0 3 3 3 0 CLASP N terminal Vac14_Fab1_bd PF12755.2 CCU99678.1 - 0.027 14.8 0.5 11 6.4 0.2 3.9 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CCU99678.1 - 0.055 13.9 29.2 0.16 12.5 0.8 8.0 8 1 1 9 9 9 0 HEAT-like repeat Sec7_N PF12783.2 CCU99678.1 - 0.35 10.2 5.5 0.5 9.7 0.2 3.3 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal BRO1 PF03097.13 CCU99679.1 - 1.6e-55 188.4 0.9 1.6e-55 188.4 0.6 1.9 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CCU99679.1 - 1.5e-48 165.3 0.5 2.6e-48 164.5 0.4 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV MxiH PF09392.5 CCU99679.1 - 0.029 14.9 5.4 2.9 8.5 0.0 4.4 2 1 1 3 3 3 0 Type III secretion needle MxiH like zf-RING_2 PF13639.1 CCU99680.1 - 1.2e-14 53.8 11.0 2e-14 53.1 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCU99680.1 - 2.9e-10 40.1 4.8 5e-10 39.3 3.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CCU99680.1 - 1.8e-07 31.0 9.6 2.9e-07 30.4 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCU99680.1 - 3.2e-07 29.9 9.7 5.4e-07 29.1 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCU99680.1 - 5.6e-07 29.1 8.7 9e-07 28.5 6.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCU99680.1 - 5.7e-07 29.1 6.6 9.1e-07 28.4 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCU99680.1 - 2.3e-05 24.1 2.7 4.5e-05 23.2 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 CCU99680.1 - 0.0066 16.4 2.6 0.015 15.2 1.8 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-RING-like PF08746.6 CCU99680.1 - 0.015 15.2 9.7 0.027 14.4 6.7 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.2 CCU99680.1 - 0.027 14.5 12.2 0.047 13.7 8.5 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 CCU99680.1 - 0.032 13.8 6.4 0.057 13.0 4.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.1 CCU99680.1 - 0.036 14.2 2.7 0.084 13.0 1.8 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 CCU99680.1 - 0.043 13.5 6.6 0.1 12.3 4.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCU99680.1 - 0.31 10.9 8.1 3.3 7.6 5.6 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 CCU99680.1 - 0.32 10.5 3.2 0.65 9.5 2.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TFIIA PF03153.8 CCU99680.1 - 7.3 6.3 14.3 11 5.7 9.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FANCL_C PF11793.3 CCU99680.1 - 8.4 6.4 10.2 24 4.9 7.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain SH3_2 PF07653.12 CCU99681.1 - 1e-06 28.1 0.0 1.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCU99681.1 - 1.9e-05 23.9 0.0 0.13 11.6 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CCU99681.1 - 0.00063 19.2 0.1 0.0019 17.7 0.1 1.8 1 1 0 1 1 1 1 Variant SH3 domain cobW PF02492.14 CCU99682.1 - 1e-49 168.4 1.3 5.2e-49 166.0 0.9 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain HIT PF01230.18 CCU99682.1 - 1.4e-28 99.2 0.2 3.7e-28 97.9 0.1 1.8 1 0 0 1 1 1 1 HIT domain CobW_C PF07683.9 CCU99682.1 - 7.2e-22 76.9 0.8 2.5e-15 55.9 0.0 3.2 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain DcpS_C PF11969.3 CCU99682.1 - 1.3e-08 35.0 0.1 2.9e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA_16 PF13191.1 CCU99682.1 - 0.00092 19.2 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ArgK PF03308.11 CCU99682.1 - 0.0092 14.7 0.1 3.5 6.3 0.0 2.2 2 0 0 2 2 2 2 ArgK protein T2SE PF00437.15 CCU99682.1 - 0.016 14.1 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 CCU99682.1 - 0.02 14.5 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 CCU99682.1 - 0.028 14.0 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 CCU99682.1 - 0.049 13.7 0.1 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 CCU99682.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 CCU99682.1 - 0.11 12.2 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 CCU99682.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCU99682.1 - 0.19 11.2 0.2 0.45 10.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 CCU99682.1 - 0.34 11.2 2.4 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain BRF1 PF07741.8 CCU99683.1 - 1.5e-24 86.0 3.2 1.5e-24 86.0 2.2 2.8 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Gag_p24 PF00607.15 CCU99683.1 - 0.35 10.3 6.6 0.17 11.4 1.2 2.1 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) TF_Zn_Ribbon PF08271.7 CCU99684.1 - 6.3e-10 38.2 0.2 9.1e-10 37.7 0.1 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 CCU99684.1 - 0.00031 19.8 0.3 0.00056 19.0 0.2 1.5 1 0 0 1 1 1 1 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CCU99684.1 - 0.069 12.8 0.2 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DZR PF12773.2 CCU99684.1 - 0.12 12.1 0.9 0.26 11.1 0.6 1.6 1 1 0 1 1 1 0 Double zinc ribbon DUF35_N PF12172.3 CCU99684.1 - 0.21 11.5 0.8 19 5.3 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-NADH-PPase PF09297.6 CCU99684.1 - 0.69 9.4 3.2 12 5.5 0.3 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.1 CCU99684.1 - 1.2 8.6 4.4 12 5.5 3.1 2.2 1 1 0 1 1 1 0 zinc-ribbon domain GATA PF00320.22 CCU99684.1 - 4.8 6.6 6.4 6.1 6.2 0.0 2.7 3 0 0 3 3 3 0 GATA zinc finger HisG PF01634.13 CCU99685.1 - 5.4e-50 169.1 0.1 7.8e-50 168.6 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 CCU99685.1 - 1.7e-26 91.9 0.1 3.2e-26 91.0 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 CCU99685.1 - 0.0058 16.2 0.1 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 CCU99685.1 - 0.021 14.0 0.0 0.044 13.0 0.0 1.6 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 ETF_alpha PF00766.14 CCU99685.1 - 0.06 12.9 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain AAA PF00004.24 CCU99686.1 - 4.2e-39 133.7 0.0 7.5e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCU99686.1 - 1e-06 27.9 0.0 1.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCU99686.1 - 1.5e-06 28.3 0.1 0.00069 19.6 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 CCU99686.1 - 2.9e-06 27.4 0.2 9.8e-05 22.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCU99686.1 - 9.4e-06 26.4 0.0 2.1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CCU99686.1 - 1.4e-05 25.0 0.0 3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCU99686.1 - 2.3e-05 24.1 0.3 0.00015 21.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CCU99686.1 - 4.6e-05 23.3 0.0 9.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCU99686.1 - 5.4e-05 23.0 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCU99686.1 - 9e-05 21.9 1.0 0.01 15.2 0.3 2.2 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CCU99686.1 - 0.00028 20.3 0.1 0.00045 19.6 0.1 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 CCU99686.1 - 0.00029 20.8 0.0 0.00064 19.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 CCU99686.1 - 0.00036 20.6 0.0 0.0019 18.3 0.0 2.2 1 1 1 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 CCU99686.1 - 0.00052 19.2 0.2 0.0013 17.9 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CCU99686.1 - 0.00094 19.4 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CCU99686.1 - 0.0011 17.7 0.0 0.0019 16.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 CCU99686.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCU99686.1 - 0.002 18.1 0.1 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCU99686.1 - 0.0027 16.8 0.1 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 CCU99686.1 - 0.0038 16.7 0.1 0.0094 15.4 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CCU99686.1 - 0.0052 15.6 0.0 0.0096 14.8 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Guanylate_kin PF00625.16 CCU99686.1 - 0.0058 16.0 0.0 0.033 13.6 0.0 2.2 3 0 0 3 3 2 1 Guanylate kinase AAA_19 PF13245.1 CCU99686.1 - 0.0078 15.9 1.3 0.014 15.1 0.3 1.8 2 0 0 2 2 1 1 Part of AAA domain KaiC PF06745.8 CCU99686.1 - 0.0082 15.2 0.1 0.2 10.7 0.0 2.3 1 1 1 2 2 2 1 KaiC DUF815 PF05673.8 CCU99686.1 - 0.0091 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 CCU99686.1 - 0.012 15.3 0.0 0.021 14.4 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein NACHT PF05729.7 CCU99686.1 - 0.012 15.2 0.1 0.033 13.8 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.1 CCU99686.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CCU99686.1 - 0.026 13.7 0.2 0.14 11.3 0.1 2.0 2 1 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.6 CCU99686.1 - 0.032 13.8 0.0 0.098 12.2 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 CCU99686.1 - 0.034 14.0 0.7 4.9 7.0 0.0 2.4 2 1 1 3 3 2 0 AAA domain IPT PF01745.11 CCU99686.1 - 0.054 12.6 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Arch_ATPase PF01637.13 CCU99686.1 - 0.055 13.1 0.0 0.95 9.1 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase CPT PF07931.7 CCU99686.1 - 0.062 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein UPF0079 PF02367.12 CCU99686.1 - 0.064 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 CCU99686.1 - 0.067 13.0 0.1 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase ABC_tran PF00005.22 CCU99686.1 - 0.095 12.9 0.2 0.33 11.2 0.0 1.8 2 1 0 2 2 1 0 ABC transporter Rad17 PF03215.10 CCU99686.1 - 0.16 10.6 0.0 0.3 9.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 CCU99686.1 - 0.19 11.3 0.7 0.68 9.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 CCU99686.1 - 0.2 10.5 0.7 2.3 7.1 0.1 2.1 1 1 1 2 2 2 0 KAP family P-loop domain Proteasome PF00227.21 CCU99687.1 - 6.5e-41 139.7 0.0 7.4e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cation_efflux PF01545.16 CCU99688.1 - 1.1e-10 41.0 3.8 1.1e-10 41.0 2.6 1.9 2 0 0 2 2 2 1 Cation efflux family DNA_pol_delta_4 PF04081.8 CCU99689.1 - 1.1e-11 45.1 0.0 1.4e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 MT0933_antitox PF14013.1 CCU99689.1 - 0.067 13.3 0.4 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 MT0933-like antitoxin protein Met_10 PF02475.11 CCU99690.1 - 3.1e-61 206.4 0.0 4.2e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 CCU99690.1 - 0.0022 18.0 0.9 0.0022 18.0 0.6 2.4 2 2 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CCU99690.1 - 0.042 13.2 0.0 0.096 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain zf-RING-like PF08746.6 CCU99690.1 - 0.29 11.1 1.7 12 5.9 0.1 2.5 2 0 0 2 2 2 0 RING-like domain Bromodomain PF00439.20 CCU99691.1 - 6.8e-11 41.9 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DUF2984 PF11203.3 CCU99691.1 - 0.051 13.6 3.0 0.33 11.0 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2984) Acyltransferase PF01553.16 CCU99692.1 - 4.4e-18 64.9 0.0 6e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase zf-Tim10_DDP PF02953.10 CCU99693.1 - 7.1e-10 38.0 2.9 1.3e-07 30.8 2.0 2.2 1 1 0 1 1 1 1 Tim10/DDP family zinc finger NPH3 PF03000.9 CCU99693.1 - 0.016 14.7 0.0 0.017 14.6 0.0 1.0 1 0 0 1 1 1 0 NPH3 family Pil1 PF13805.1 CCU99694.1 - 8.8e-07 28.3 0.4 8.8e-07 28.3 0.3 2.0 2 0 0 2 2 2 1 Eisosome component PIL1 MRG PF05712.8 CCU99695.1 - 5.2e-56 188.6 0.0 7.6e-56 188.1 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 CCU99695.1 - 3.9e-09 36.0 0.2 9.8e-09 34.7 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 CCU99695.1 - 0.023 14.3 1.7 0.068 12.8 1.2 1.9 1 1 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1956 PF09209.6 CCU99695.1 - 0.029 14.3 0.1 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1956) BAR_2 PF10455.4 CCU99696.1 - 9.6e-36 123.1 0.6 2.6e-27 95.5 0.1 2.1 1 1 1 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 CCU99696.1 - 1.1e-14 54.5 6.0 7e-14 51.8 4.1 1.9 1 1 0 1 1 1 1 BAR domain zf-C4H2 PF10146.4 CCU99696.1 - 0.00024 21.2 1.0 0.00024 21.2 0.7 2.0 2 1 0 2 2 2 1 Zinc finger-containing protein BLOC1_2 PF10046.4 CCU99696.1 - 0.011 15.8 2.0 1.8 8.7 0.1 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.1 CCU99696.1 - 0.017 14.2 3.1 0.86 8.7 0.0 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4618 PF15397.1 CCU99696.1 - 0.043 13.1 4.0 0.18 11.1 0.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF16 PF01519.11 CCU99696.1 - 0.11 12.6 3.0 3.4 7.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function DUF16 Flagellin_N PF00669.15 CCU99696.1 - 0.14 11.9 8.3 1.1 9.0 0.3 3.0 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region Prefoldin_2 PF01920.15 CCU99696.1 - 0.18 11.5 4.0 4.1 7.2 0.1 3.4 3 0 0 3 3 3 0 Prefoldin subunit DUF848 PF05852.6 CCU99696.1 - 0.25 11.1 4.3 0.39 10.5 0.1 2.5 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Seryl_tRNA_N PF02403.17 CCU99696.1 - 0.52 10.3 5.4 2.5 8.1 0.1 3.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Allexi_40kDa PF05549.6 CCU99696.1 - 0.68 9.1 3.9 0.51 9.5 0.1 2.2 2 1 0 2 2 2 0 Allexivirus 40kDa protein Uds1 PF15456.1 CCU99696.1 - 0.85 9.6 8.7 0.19 11.7 0.3 3.0 2 2 1 3 3 3 0 Up-regulated During Septation ATG16 PF08614.6 CCU99696.1 - 1.3 8.8 10.1 3.6 7.3 0.5 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CPSase_L_D2 PF02786.12 CCU99697.1 - 1.5e-115 383.8 0.1 9.9e-84 279.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 CCU99697.1 - 8.1e-46 154.7 0.0 5.2e-45 152.1 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 CCU99697.1 - 3.2e-43 146.7 0.1 7.7e-43 145.5 0.0 1.8 2 0 0 2 2 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 CCU99697.1 - 6.7e-43 145.3 0.1 1.3e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GATase PF00117.23 CCU99697.1 - 9.2e-42 142.6 0.0 1.8e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 CCU99697.1 - 1.7e-39 134.3 0.0 3.6e-20 72.1 0.0 3.2 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 CCU99697.1 - 1.9e-36 125.3 0.0 3.8e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 CCU99697.1 - 3.3e-36 124.7 0.1 6.5e-23 81.4 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCU99697.1 - 1.6e-20 73.1 0.0 3e-12 45.9 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 CCU99697.1 - 4e-17 62.2 0.0 7.3e-09 35.2 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CCU99697.1 - 4.4e-16 58.7 0.0 2.2e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 CCU99697.1 - 1.1e-12 47.6 0.0 1.3e-11 44.2 0.0 2.9 3 0 0 3 3 3 1 MGS-like domain ATP-grasp_3 PF02655.9 CCU99697.1 - 4.9e-08 33.0 0.1 0.0018 18.1 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 CCU99697.1 - 6.7e-05 22.4 0.3 0.0038 16.6 0.2 2.7 1 1 0 1 1 1 1 Peptidase C26 Hydrolase PF00702.21 CCU99697.1 - 0.027 14.9 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase RimK PF08443.6 CCU99697.1 - 0.044 13.2 0.0 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain DUF2827 PF10933.3 CCU99697.1 - 0.17 10.3 0.0 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) CBFD_NFYB_HMF PF00808.18 CCU99698.1 - 7e-18 64.4 0.2 1.3e-17 63.6 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCU99698.1 - 7.7e-08 32.3 0.2 1.2e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 CCU99698.1 - 0.035 13.9 0.1 0.051 13.3 0.1 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region CENP-X PF09415.5 CCU99698.1 - 0.16 11.7 0.9 0.18 11.6 0.0 1.5 2 0 0 2 2 2 0 CENP-S associating Centromere protein X CMS1 PF14617.1 CCU99699.1 - 1.3e-35 122.7 0.0 1.2e-34 119.4 0.0 2.2 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 CCU99699.1 - 0.026 14.0 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase RRM_6 PF14259.1 CCU99702.1 - 1.1e-09 38.1 0.0 1.6e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCU99702.1 - 3.4e-06 26.6 0.0 1e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99702.1 - 3.5e-05 23.5 0.0 8.5e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4456 PF14644.1 CCU99702.1 - 0.02 14.1 1.6 0.02 14.1 1.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4456) Rad60-SLD PF11976.3 CCU99703.1 - 6.6e-25 86.6 0.3 7.7e-25 86.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CCU99703.1 - 5.1e-11 41.7 0.0 6.3e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF4115 PF13464.1 CCU99703.1 - 0.034 13.8 0.0 0.057 13.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4115) DUF3085 PF11284.3 CCU99703.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) TPR_11 PF13414.1 CCU99704.1 - 3.2e-53 177.2 9.5 2e-18 65.7 0.3 6.6 4 2 2 6 6 6 6 TPR repeat TPR_1 PF00515.23 CCU99704.1 - 8.8e-45 148.5 4.5 1.2e-06 27.8 0.0 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 CCU99704.1 - 1.6e-40 133.7 6.2 1.1e-05 25.0 0.0 11.3 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_12 PF13424.1 CCU99704.1 - 2.9e-29 100.7 13.9 2.8e-07 30.3 0.5 6.9 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 CCU99704.1 - 1.3e-27 95.8 7.7 1.6e-06 28.5 0.3 6.2 5 1 0 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCU99704.1 - 8.1e-23 78.4 2.2 0.0077 15.9 0.0 9.8 8 2 1 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCU99704.1 - 1.9e-20 71.3 3.9 0.00018 21.4 0.0 8.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCU99704.1 - 5.7e-18 63.7 3.7 0.0026 18.2 0.0 9.1 3 2 7 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCU99704.1 - 2.3e-14 53.4 6.8 0.023 15.0 0.0 6.0 5 1 0 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 CCU99704.1 - 7.3e-13 48.4 6.0 0.0025 17.8 0.1 4.6 2 1 4 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CCU99704.1 - 3.9e-11 41.8 2.6 3.2 7.7 0.0 7.3 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 CCU99704.1 - 5.1e-10 39.0 0.1 1e-05 25.2 0.0 5.6 2 1 6 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCU99704.1 - 1e-07 31.9 4.8 1.8 9.2 0.0 8.8 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCU99704.1 - 1.3e-06 27.7 3.6 0.021 13.8 0.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc5 PF12862.2 CCU99704.1 - 0.00017 21.3 4.3 0.27 11.0 0.0 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 5 TPR_4 PF07721.9 CCU99704.1 - 0.0041 17.3 0.2 0.44 11.1 0.0 4.3 5 0 0 5 5 3 1 Tetratricopeptide repeat NARP1 PF12569.3 CCU99704.1 - 0.012 14.4 0.2 0.16 10.7 0.0 4.3 2 2 4 6 6 6 0 NMDA receptor-regulated protein 1 MIT PF04212.13 CCU99704.1 - 0.13 12.1 2.8 0.56 10.1 0.1 3.5 4 0 0 4 4 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 CCU99704.1 - 0.21 11.5 14.1 13 5.8 0.2 8.0 10 1 0 10 10 9 0 Tetratricopeptide repeat F-box-like PF12937.2 CCU99705.1 - 0.054 13.2 2.0 0.092 12.4 0.3 2.3 2 1 0 2 2 2 0 F-box-like F-box PF00646.28 CCU99705.1 - 0.08 12.6 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 F-box domain CRAL_TRIO PF00650.15 CCU99706.1 - 6.9e-26 90.6 0.0 9.8e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCU99706.1 - 4e-06 26.8 0.4 2e-05 24.6 0.2 2.3 2 1 1 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CCU99706.1 - 0.0037 17.1 0.0 0.008 16.0 0.0 1.5 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain EOS1 PF12326.3 CCU99707.1 - 5e-15 55.4 0.0 9.2e-15 54.5 0.0 1.4 1 1 0 1 1 1 1 N-glycosylation protein TT_ORF1 PF02956.9 CCU99707.1 - 2.9 6.2 9.1 3 6.1 6.3 1.1 1 0 0 1 1 1 0 TT viral orf 1 Mago_nashi PF02792.9 CCU99708.1 - 8.8e-65 216.7 0.4 9.9e-65 216.6 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Cpn10 PF00166.16 CCU99709.1 - 2.2e-26 91.6 0.0 2.5e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.19 CCU99710.1 - 1e-123 413.5 2.6 1.2e-123 413.3 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mito_carr PF00153.22 CCU99711.1 - 4.1e-72 237.9 0.6 3e-24 84.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SMC_N PF02463.14 CCU99712.1 - 7.6e-68 228.0 0.0 1.8e-67 226.7 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCU99712.1 - 1.5e-21 76.5 2.4 1e-19 70.6 0.9 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CCU99712.1 - 1.6e-18 67.8 1.1 1.6e-18 67.8 0.8 4.8 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.1 CCU99712.1 - 2.3e-13 50.7 2.4 2e-06 27.9 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCU99712.1 - 2.3e-05 23.7 0.0 8e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CCU99712.1 - 6.5e-05 22.1 0.0 0.00014 21.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 CCU99712.1 - 0.0068 16.6 15.7 0.41 10.9 0.0 5.2 4 1 0 4 4 4 2 ABC transporter IgG_binding_B PF01378.12 CCU99712.1 - 0.032 14.0 0.5 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 B domain Ribosomal_S27 PF01599.14 CCU99712.1 - 0.16 11.8 1.8 0.17 11.7 0.2 1.8 2 0 0 2 2 2 0 Ribosomal protein S27a Reo_sigmaC PF04582.7 CCU99712.1 - 1.8 7.6 22.5 0.71 9.0 0.2 5.1 3 2 1 5 5 5 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 CCU99712.1 - 9.5 6.2 8.9 13 5.7 0.1 5.2 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) DNA_ligase_A_N PF04675.9 CCU99713.1 - 3.6e-52 176.7 0.3 5.2e-52 176.2 0.2 1.2 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 CCU99713.1 - 5.1e-52 176.1 0.0 7.7e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain eIF-3c_N PF05470.7 CCU99713.1 - 0.22 9.5 0.0 0.28 9.2 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Peptidase_M48 PF01435.13 CCU99714.1 - 1.5e-38 132.6 0.0 2.8e-38 131.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M13 PF01431.16 CCU99714.1 - 0.17 11.0 0.1 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M13 GTP_EFTU PF00009.22 CCU99715.1 - 8.2e-56 188.4 0.0 1.4e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCU99715.1 - 4.1e-37 126.4 0.0 8.1e-37 125.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 CCU99715.1 - 8.2e-31 105.6 0.0 1.7e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CCU99715.1 - 4.5e-23 80.9 0.0 9.9e-23 79.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCU99715.1 - 2.6e-13 49.8 0.0 1e-12 47.9 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Sigma70_r3 PF04539.11 CCU99715.1 - 0.045 13.6 1.6 5.3 7.0 0.3 2.7 2 0 0 2 2 2 0 Sigma-70 region 3 TFIID-18kDa PF02269.11 CCU99716.1 - 8.6e-32 108.8 0.9 4.8e-28 96.8 0.4 2.4 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit tRNA-synt_1b PF00579.20 CCU99716.1 - 0.065 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) SlyX PF04102.7 CCU99717.1 - 0.23 11.8 3.4 0.54 10.6 0.2 2.8 2 0 0 2 2 2 0 SlyX Peptidase_S46 PF10459.4 CCU99717.1 - 1.1 7.5 7.5 2 6.7 5.2 1.3 1 0 0 1 1 1 0 Peptidase S46 PLA2_B PF01735.13 CCU99718.1 - 5.3e-17 61.1 0.0 2.4e-08 32.6 0.0 3.1 3 0 0 3 3 3 3 Lysophospholipase catalytic domain OEP PF02321.13 CCU99718.1 - 0.14 11.7 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein Ribosomal_S10 PF00338.17 CCU99719.1 - 4.3e-19 68.1 0.0 6.2e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e BTB_2 PF02214.17 CCU99720.1 - 0.0058 16.8 0.0 0.44 10.7 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain FAP PF07174.6 CCU99720.1 - 0.021 14.1 1.4 0.045 13.0 1.0 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Exostosin PF03016.10 CCU99720.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Exostosin family Longin PF13774.1 CCU99721.1 - 2.5e-25 87.8 0.0 3.7e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CCU99721.1 - 0.0001 21.8 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 Synaptobrevin Septin PF00735.13 CCU99722.1 - 2.9e-110 367.7 0.0 3.8e-110 367.3 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CCU99722.1 - 4e-07 29.9 0.0 7.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CCU99722.1 - 3.4e-05 23.9 0.5 0.0034 17.5 0.0 3.1 2 2 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 CCU99722.1 - 0.00032 20.5 1.6 0.35 10.6 0.0 2.7 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 CCU99722.1 - 0.00037 19.7 0.1 0.0016 17.6 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 CCU99722.1 - 0.00042 19.7 0.2 0.0017 17.7 0.1 2.0 2 1 0 2 2 2 1 Ras family GTP_EFTU PF00009.22 CCU99722.1 - 0.0006 19.3 0.1 0.018 14.5 0.1 2.7 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CCU99722.1 - 0.0011 18.9 2.2 0.0036 17.2 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 CCU99722.1 - 0.0021 17.5 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain PduV-EutP PF10662.4 CCU99722.1 - 0.0021 17.5 0.1 0.64 9.5 0.1 2.5 1 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CCU99722.1 - 0.0075 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CCU99722.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 CCU99722.1 - 0.011 16.2 0.0 0.027 14.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Gtr1_RagA PF04670.7 CCU99722.1 - 0.012 14.7 0.0 0.069 12.2 0.0 2.2 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region AIG1 PF04548.11 CCU99722.1 - 0.017 14.2 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_24 PF13479.1 CCU99722.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCU99722.1 - 0.054 13.6 0.0 0.61 10.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 CCU99722.1 - 0.058 13.2 0.4 0.22 11.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CCU99722.1 - 0.33 11.2 2.8 7 6.9 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CCU99722.1 - 0.63 10.8 2.5 3.1 8.6 1.7 2.5 1 1 0 1 1 1 0 AAA domain zf-met PF12874.2 CCU99723.1 - 1.6e-06 28.1 1.1 3.2e-06 27.1 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Pyr_redox_3 PF13738.1 CCU99724.1 - 9.7e-05 22.5 0.9 0.025 14.6 0.2 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCU99724.1 - 0.00076 19.4 0.4 0.0025 17.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CCU99724.1 - 0.00092 19.0 4.0 0.0079 15.9 0.1 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCU99724.1 - 0.0069 16.2 0.0 1.2 8.9 0.0 2.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCU99724.1 - 0.011 14.8 0.2 8 5.4 0.0 3.1 3 0 0 3 3 3 0 Thi4 family Pyr_redox PF00070.22 CCU99724.1 - 0.012 15.9 0.1 0.58 10.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCU99724.1 - 0.18 10.7 0.5 9.8 4.9 0.0 2.8 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 CCU99724.1 - 0.24 9.7 0.3 0.49 8.7 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Ras PF00071.17 CCU99725.1 - 1.3e-54 184.0 0.0 1.5e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU99725.1 - 7.3e-18 65.1 0.0 9.5e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCU99725.1 - 9.5e-15 54.2 0.0 1.3e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCU99725.1 - 3.6e-06 26.9 0.0 4.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCU99725.1 - 3.8e-05 22.9 0.0 4.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 CCU99725.1 - 0.0012 18.8 0.4 0.003 17.5 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCU99725.1 - 0.0029 17.7 0.0 0.012 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCU99725.1 - 0.0033 16.6 0.2 0.013 14.7 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCU99725.1 - 0.0037 16.7 0.0 0.0092 15.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF815 PF05673.8 CCU99725.1 - 0.0085 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 CCU99725.1 - 0.018 14.5 0.1 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 CCU99725.1 - 0.022 14.4 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CCU99725.1 - 0.35 11.7 2.1 3 8.6 1.4 2.2 1 1 0 1 1 1 0 AAA domain TruD PF01142.13 CCU99726.1 - 3e-61 207.1 0.0 1.4e-60 204.9 0.0 1.9 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) HemY_N PF07219.8 CCU99726.1 - 3 7.4 6.6 0.99 8.9 0.1 3.1 3 1 1 4 4 4 0 HemY protein N-terminus Ammonium_transp PF00909.16 CCU99727.1 - 2.1e-111 372.2 21.2 2.3e-111 372.0 14.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family YqzM PF14141.1 CCU99727.1 - 0.36 10.6 2.5 0.55 10.0 0.3 2.5 2 0 0 2 2 2 0 YqzM-like protein ENTH PF01417.15 CCU99728.1 - 7.4e-42 142.1 0.2 1.7e-41 140.9 0.1 1.6 1 1 0 1 1 1 1 ENTH domain ANTH PF07651.11 CCU99728.1 - 0.069 11.8 5.5 0.014 14.1 1.1 1.7 1 1 0 2 2 2 0 ANTH domain PAT1 PF09770.4 CCU99728.1 - 2 6.5 34.7 2.9 6.0 24.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CCU99728.1 - 4.5 4.8 8.8 5.8 4.4 6.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3367 PF11847.3 CCU99728.1 - 6.4 4.5 6.1 8.9 4.1 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) Na_Ca_ex PF01699.19 CCU99729.1 - 1.7e-36 124.8 27.9 2.4e-19 69.3 7.0 2.6 2 1 0 2 2 2 2 Sodium/calcium exchanger protein TPR_17 PF13431.1 CCU99730.1 - 7e-06 25.8 1.2 3.3 8.1 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCU99730.1 - 0.0044 16.6 17.6 0.034 13.8 0.4 6.1 5 2 2 7 7 7 3 TPR repeat TPR_16 PF13432.1 CCU99730.1 - 0.0046 17.5 6.3 0.0046 17.5 4.4 8.4 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCU99730.1 - 0.014 15.2 16.5 0.18 11.7 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Tubulin PF00091.20 CCU99731.1 - 1e-71 241.2 0.0 1.9e-71 240.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCU99731.1 - 1e-48 164.5 0.3 1.6e-48 163.9 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CCU99731.1 - 1.4e-06 28.2 0.0 3.5e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CCU99731.1 - 0.00067 19.1 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Saccharop_dh PF03435.13 CCU99732.1 - 2.6e-103 346.0 0.0 4.6e-103 345.1 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 CCU99732.1 - 1.8e-88 295.6 0.0 4.8e-88 294.2 0.0 1.7 2 0 0 2 2 2 1 Spermine/spermidine synthase Semialdhyde_dh PF01118.19 CCU99732.1 - 6.9e-05 23.1 0.1 0.00057 20.1 0.0 2.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCU99732.1 - 8.9e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCU99732.1 - 0.00047 19.6 0.0 0.00099 18.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 CCU99732.1 - 0.0075 16.5 0.2 0.3 11.3 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding F420_oxidored PF03807.12 CCU99732.1 - 0.0097 16.3 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 CCU99732.1 - 0.028 14.5 0.0 0.36 10.9 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 CCU99732.1 - 0.043 14.3 0.0 0.22 12.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DUF2325 PF10087.4 CCU99732.1 - 0.056 13.2 0.2 0.97 9.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) 3Beta_HSD PF01073.14 CCU99732.1 - 0.058 12.0 0.0 0.088 11.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CCU99732.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family IlvN PF07991.7 CCU99732.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Ank PF00023.25 CCU99733.1 - 1.1e-34 116.4 7.2 2.1e-11 42.9 0.1 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 CCU99733.1 - 3.4e-30 104.2 1.7 3.4e-14 52.9 0.0 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CCU99733.1 - 2.6e-26 89.0 0.4 1e-07 31.4 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 CCU99733.1 - 4.3e-26 90.3 3.8 1.4e-07 31.5 0.1 4.3 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCU99733.1 - 6.8e-25 86.9 1.7 7.2e-08 32.7 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) SsgA PF04686.7 CCU99733.1 - 0.098 12.3 0.0 0.6 9.8 0.0 2.1 2 0 0 2 2 2 0 Streptomyces sporulation and cell division protein, SsgA Prenyltrans_2 PF13249.1 CCU99734.1 - 7.9e-32 110.0 5.6 1.3e-16 61.0 0.1 4.7 2 2 3 5 5 5 3 Prenyltransferase-like Prenyltrans PF00432.16 CCU99734.1 - 8.5e-32 108.3 4.3 1.4e-09 37.2 0.1 6.3 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 CCU99734.1 - 2.5e-26 91.8 0.4 6.3e-14 51.8 0.2 5.5 4 1 0 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 CCU99734.1 - 2.4e-07 30.2 0.3 0.12 11.5 0.0 4.3 1 1 2 4 4 4 2 Pectic acid lyase A2M_comp PF07678.9 CCU99734.1 - 4.4e-06 26.1 0.0 0.0041 16.3 0.0 3.4 2 1 2 4 4 4 2 A-macroglobulin complement component Mago-bind PF09282.5 CCU99734.1 - 0.0011 18.5 0.3 1.1 8.8 0.0 2.9 3 0 0 3 3 3 2 Mago binding ANTAR PF03861.9 CCU99734.1 - 0.11 12.1 0.1 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 ANTAR domain Pex16 PF08610.5 CCU99735.1 - 7.5e-70 235.5 1.4 4.4e-69 233.0 1.0 1.9 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) ATG13 PF10033.4 CCU99736.1 - 2.4e-37 128.5 0.0 5.3e-37 127.4 0.0 1.6 1 1 0 1 1 1 1 Autophagy-related protein 13 Pkinase PF00069.20 CCU99737.1 - 2.7e-53 180.7 0.0 3.4e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99737.1 - 1.3e-36 125.9 0.0 9.6e-35 119.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCU99737.1 - 8.3e-09 34.8 0.0 2e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCU99737.1 - 0.0028 17.4 0.1 0.085 12.5 0.0 2.9 3 1 1 4 4 4 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCU99737.1 - 0.032 13.0 0.1 0.051 12.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_transf_22 PF03901.12 CCU99738.1 - 4.1e-66 223.7 16.4 4.7e-45 154.3 7.9 2.2 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family NatB_MDM20 PF09797.4 CCU99738.1 - 1.7e-40 138.8 0.0 1.8e-30 105.9 0.0 2.4 1 1 1 2 2 2 2 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 CCU99738.1 - 5.6 7.8 16.9 30 5.6 0.1 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat ERCC4 PF02732.10 CCU99739.1 - 2.8e-09 36.8 0.0 4.7e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 ERCC4 domain SIR2 PF02146.12 CCU99740.1 - 6.4e-21 74.8 0.0 5.7e-20 71.7 0.0 2.0 1 1 0 1 1 1 1 Sir2 family DUF364 PF04016.7 CCU99740.1 - 0.1 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF364) PRA1 PF03208.14 CCU99741.1 - 5.3e-38 129.7 2.5 6.1e-38 129.5 1.7 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF2516 PF10724.4 CCU99741.1 - 8.3 6.4 7.7 13 5.8 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2516) Telomerase_RBD PF12009.3 CCU99742.1 - 8.8e-31 106.6 2.9 1.5e-30 105.9 2.0 1.4 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CCU99742.1 - 4.1e-12 45.9 0.0 3.1e-11 43.0 0.0 2.3 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 CCU99743.1 - 8.4e-86 279.0 10.1 9.1e-10 38.0 0.0 12.1 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.6 CCU99743.1 - 6.1e-37 126.4 0.2 1.2e-36 125.4 0.2 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 CCU99743.1 - 5.9e-10 37.9 10.8 0.35 8.9 0.6 6.7 4 2 2 7 7 7 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCU99743.1 - 1.1e-06 27.7 0.0 1.3 7.6 0.0 5.4 4 1 0 5 5 5 2 Nup133 N terminal like SIP PF04954.8 CCU99743.1 - 0.0044 17.3 2.0 0.072 13.4 0.3 2.8 2 0 0 2 2 2 1 Siderophore-interacting protein US22 PF02393.11 CCU99743.1 - 0.04 13.9 1.2 13 5.8 0.1 3.0 3 0 0 3 3 3 0 US22 like SF3b1 PF08920.5 CCU99744.1 - 6.4e-20 71.6 11.3 2.8e-15 56.6 7.8 3.5 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 CCU99744.1 - 2.3e-19 69.4 11.1 2.6e-06 27.5 0.1 8.1 6 2 2 8 8 8 3 HEAT repeats HEAT PF02985.17 CCU99744.1 - 5.1e-12 44.8 8.6 0.39 10.9 0.0 10.8 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 CCU99744.1 - 1.4e-10 41.3 13.7 0.027 14.9 0.0 9.6 8 2 2 10 10 10 3 HEAT-like repeat Adaptin_N PF01602.15 CCU99744.1 - 2.4e-06 26.1 0.2 0.086 11.1 0.1 3.4 2 1 1 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 CCU99744.1 - 2.2e-05 24.7 0.2 8.4 6.8 0.0 5.3 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CCU99744.1 - 0.00083 18.7 2.2 0.23 10.8 0.0 3.5 3 0 0 3 3 3 1 CLASP N terminal NUC173 PF08161.7 CCU99744.1 - 0.0036 16.6 0.7 17 4.7 0.0 4.4 5 1 0 5 5 5 0 NUC173 domain Dopey_N PF04118.9 CCU99744.1 - 0.006 15.3 0.2 0.03 13.1 0.0 2.2 3 0 0 3 3 3 1 Dopey, N-terminal Arm PF00514.18 CCU99744.1 - 0.062 13.1 0.0 63 3.6 0.0 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat RRM_6 PF14259.1 CCU99746.1 - 0.00041 20.2 0.0 0.00074 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCU99746.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99746.1 - 0.2 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S2 PF00318.15 CCU99747.1 - 8.3e-44 149.3 0.0 1.6e-40 138.5 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 Ribosomal_S5 PF00333.15 CCU99748.1 - 2.1e-28 97.8 0.5 4.9e-28 96.6 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CCU99748.1 - 6.4e-22 76.6 0.0 1.1e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain F1F0-ATPsyn_F PF10791.4 CCU99749.1 - 2.8e-28 97.9 0.1 5.5e-28 97.0 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi BRO1 PF03097.13 CCU99749.1 - 8.7e-14 51.0 0.0 1.3e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain NAP PF00956.13 CCU99750.1 - 3.6e-78 262.0 0.7 3.6e-78 262.0 0.5 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Nucleoplasmin PF03066.10 CCU99750.1 - 1.4 8.4 26.2 1.3 8.5 6.8 3.2 3 0 0 3 3 3 0 Nucleoplasmin Vps53_N PF04100.7 CCU99751.1 - 1e-68 231.9 0.0 1.6e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal COG7 PF10191.4 CCU99751.1 - 0.0057 14.6 3.3 0.094 10.6 1.0 2.2 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) ETC_C1_NDUFA4 PF04800.7 CCU99753.1 - 5.6e-31 106.3 0.0 9.4e-31 105.6 0.0 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region ATP_bind_1 PF03029.12 CCU99754.1 - 2.9e-40 138.3 0.0 1.5e-36 126.1 0.0 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein FdhE PF04216.7 CCU99755.1 - 0.015 15.0 0.8 0.78 9.3 0.1 2.6 2 1 1 3 3 3 0 Protein involved in formate dehydrogenase formation HSA PF07529.8 CCU99756.1 - 4.3e-16 58.4 7.0 4.3e-16 58.4 4.8 3.4 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 CCU99756.1 - 2.5e-05 24.2 3.3 6.2e-05 23.0 2.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SpoIIE PF07228.7 CCU99757.1 - 1e-10 41.6 0.0 1.7e-08 34.4 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CCU99757.1 - 1e-08 34.8 0.1 2.8e-08 33.4 0.1 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CCU99757.1 - 4e-07 29.6 0.0 0.00076 18.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Isochorismatase PF00857.15 CCU99758.1 - 5.1e-21 75.3 0.8 1.7e-20 73.7 0.6 1.8 1 1 0 1 1 1 1 Isochorismatase family TRP PF06011.7 CCU99759.1 - 8.9e-24 83.8 10.3 5.5e-23 81.2 7.1 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CCU99759.1 - 2.7e-22 79.3 0.1 4.4e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 ML-like domain KH_1 PF00013.24 CCU99760.1 - 3.2e-68 225.2 0.6 1.2e-14 53.7 0.1 10.6 11 0 0 11 11 11 7 KH domain KH_3 PF13014.1 CCU99760.1 - 6.1e-45 150.1 0.5 1.2e-09 37.5 0.0 9.1 9 0 0 9 9 9 5 KH domain KH_2 PF07650.12 CCU99760.1 - 3.3e-09 36.1 2.6 0.096 12.2 0.1 6.3 7 0 0 7 7 7 3 KH domain KH_4 PF13083.1 CCU99760.1 - 0.00022 20.8 0.2 16 5.1 0.0 5.8 6 0 0 6 6 6 2 KH domain MFS_1 PF07690.11 CCU99761.1 - 4.3e-16 58.5 39.9 2.6e-12 46.1 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCU99761.1 - 1.6e-08 33.6 20.3 8.4e-08 31.2 6.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter WD40 PF00400.27 CCU99762.1 - 9.5e-16 57.0 3.3 3.1e-08 33.1 0.1 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.1 CCU99762.1 - 3.1 8.1 15.7 6.1 7.2 0.0 5.2 5 0 0 5 5 5 0 PQQ-like domain Metallophos PF00149.23 CCU99763.1 - 8.5e-10 38.3 0.5 5.7e-09 35.6 0.4 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 CCU99764.1 - 8e-12 44.9 6.9 2.4e-11 43.3 4.8 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCU99764.1 - 0.0038 17.0 2.5 0.018 14.8 1.7 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CCU99765.1 - 0.0012 18.2 7.7 0.0036 16.7 4.0 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase DUF836 PF05768.9 CCU99766.1 - 4.5e-12 46.0 0.0 5.1e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 CCU99766.1 - 0.01 15.9 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.16 CCU99766.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family SUR7 PF06687.7 CCU99767.1 - 9.6e-08 31.8 6.6 2.9e-07 30.2 4.6 1.8 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CCU99767.1 - 0.0033 17.1 6.4 0.0066 16.1 4.4 1.5 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction tRNA-synt_1 PF00133.17 CCU99768.1 - 1.3e-38 132.4 0.0 1.2e-30 106.1 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CCU99768.1 - 3.8e-16 58.7 0.0 3.5e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CCU99768.1 - 4.6e-14 52.4 0.0 1.2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CCU99768.1 - 2e-06 27.1 0.0 3.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Med12 PF09497.5 CCU99769.1 - 8.1e-22 76.9 0.0 2.8e-21 75.2 0.0 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 MIF4G_like_2 PF09090.6 CCU99769.1 - 0.2 10.8 0.0 0.68 9.1 0.0 1.7 2 0 0 2 2 2 0 MIF4G like Med12-LCEWAV PF12145.3 CCU99769.1 - 0.51 8.7 1.8 1.5 7.2 0.7 1.8 2 0 0 2 2 2 0 Eukaryotic Mediator 12 subunit domain ARPC4 PF05856.7 CCU99770.1 - 2.4e-72 241.8 3.0 2.7e-72 241.6 2.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) SNF2_N PF00176.18 CCU99771.1 - 4.3e-66 222.7 0.1 6.6e-66 222.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 CCU99771.1 - 6e-29 100.2 0.6 6e-29 100.2 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 CCU99771.1 - 3.4e-15 55.6 0.0 1e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 CCU99771.1 - 4.3e-14 51.9 0.0 7.1e-09 35.2 0.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 CCU99771.1 - 0.00017 21.1 0.0 0.00067 19.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2422 PF10337.4 CCU99771.1 - 0.016 13.9 3.2 0.06 12.1 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) MMR_HSR1 PF01926.18 CCU99772.1 - 2e-16 59.9 0.1 1.5e-12 47.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCU99772.1 - 1.1e-08 34.4 0.1 0.00014 21.1 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 CCU99772.1 - 1e-06 28.3 0.2 0.00026 20.4 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCU99772.1 - 0.0018 18.1 1.1 0.26 11.1 0.1 2.8 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 CCU99772.1 - 0.0053 15.9 0.1 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Mito_fiss_reg PF05308.6 CCU99772.1 - 1.1 8.5 7.0 0.069 12.5 0.7 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator PALP PF00291.20 CCU99773.1 - 3.6e-74 249.7 1.3 4.6e-74 249.4 0.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 CCU99773.1 - 3.7e-41 138.6 0.0 2.2e-23 81.6 0.0 3.3 3 0 0 3 3 3 3 C-terminal regulatory domain of Threonine dehydratase ABC_membrane PF00664.18 CCU99774.1 - 3.2e-78 262.9 20.4 5.1e-40 137.6 2.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCU99774.1 - 5.2e-60 201.6 0.0 9e-30 103.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCU99774.1 - 5e-11 42.2 0.2 0.0028 16.9 0.0 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CCU99774.1 - 4.7e-08 33.2 1.3 0.067 13.3 0.6 4.8 4 1 0 4 4 4 2 AAA domain AAA_17 PF13207.1 CCU99774.1 - 2.7e-06 28.1 0.7 0.021 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCU99774.1 - 3e-06 26.6 0.3 0.043 13.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CCU99774.1 - 4.3e-06 26.8 4.9 0.0017 18.3 0.1 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 CCU99774.1 - 9e-06 25.3 1.9 0.012 15.1 0.5 3.9 3 1 0 3 3 3 1 AAA domain AAA_21 PF13304.1 CCU99774.1 - 1.4e-05 25.2 0.0 1.3 8.9 0.0 4.1 4 0 0 4 4 4 1 AAA domain ABC_ATPase PF09818.4 CCU99774.1 - 0.00011 20.9 0.0 0.015 13.8 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 CCU99774.1 - 0.00011 21.9 2.9 0.24 11.3 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 CCU99774.1 - 0.0002 20.8 3.3 0.78 9.1 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 CCU99774.1 - 0.00082 19.6 2.0 0.25 11.6 0.1 3.0 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CCU99774.1 - 0.0015 17.7 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 CCU99774.1 - 0.0018 17.7 1.5 0.38 10.1 0.1 3.4 3 0 0 3 3 3 1 AAA-like domain AAA_33 PF13671.1 CCU99774.1 - 0.0025 17.6 0.0 2 8.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 CCU99774.1 - 0.0028 17.5 0.6 0.91 9.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 CCU99774.1 - 0.0031 17.0 0.2 1.4 8.3 0.0 3.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family MobB PF03205.9 CCU99774.1 - 0.0049 16.5 0.0 2.6 7.7 0.0 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CCU99774.1 - 0.026 13.3 0.0 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 ArgK protein PRK PF00485.13 CCU99774.1 - 0.045 13.3 1.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.15 CCU99774.1 - 0.19 10.3 0.0 7.9 5.0 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.12 CCU99774.1 - 0.35 10.3 3.7 7.5 6.0 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AMP-binding PF00501.23 CCU99775.1 - 2.2e-227 754.3 11.4 2.6e-84 283.0 0.1 3.6 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 CCU99775.1 - 2.5e-64 217.0 5.8 7e-22 77.6 0.0 7.4 6 2 0 6 6 6 5 Condensation domain PP-binding PF00550.20 CCU99775.1 - 9.1e-40 134.7 1.3 2.2e-12 47.0 0.0 5.0 5 0 0 5 5 5 4 Phosphopantetheine attachment site DEAD PF00270.24 CCU99776.1 - 4.1e-39 133.7 0.0 7.4e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU99776.1 - 5.5e-20 71.0 0.1 2.7e-19 68.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 CCU99776.1 - 1.2e-17 63.4 0.4 2.9e-17 62.2 0.3 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 CCU99776.1 - 0.00058 19.7 0.0 0.0019 18.0 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PPR_3 PF13812.1 CCU99777.1 - 0.024 14.8 0.4 0.4 11.0 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 CCU99777.1 - 0.03 14.3 0.0 0.11 12.4 0.0 1.9 3 0 0 3 3 3 0 PPR repeat family Metallophos PF00149.23 CCU99778.1 - 6.4e-29 100.7 0.2 9.1e-29 100.2 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Put_Phosphatase PF06888.7 CCU99779.1 - 8.1e-51 172.4 0.0 1e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.2 CCU99779.1 - 0.033 14.3 0.0 0.058 13.5 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RhoGEF PF00621.15 CCU99780.1 - 6.1e-15 55.5 0.0 8.1e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 RhoGEF domain DUF3141 PF11339.3 CCU99780.1 - 0.012 14.0 0.0 0.08 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3141) MmgE_PrpD PF03972.9 CCU99783.1 - 9.4e-156 518.4 0.4 1.1e-155 518.1 0.3 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PALP PF00291.20 CCU99784.1 - 1.4e-59 201.8 0.1 1.6e-59 201.6 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.20 CCU99785.1 - 7.3e-55 185.9 0.0 1.1e-54 185.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99785.1 - 9.2e-22 77.3 0.0 1.4e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCU99785.1 - 0.00058 19.6 0.6 0.0014 18.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CCU99785.1 - 0.017 14.4 0.1 0.034 13.4 0.1 1.5 1 1 0 1 1 1 0 RIO1 family NUDE_C PF04880.8 CCU99786.1 - 3.4e-09 37.2 17.2 3.4e-09 37.2 11.9 3.4 2 1 0 2 2 1 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 CCU99786.1 - 0.0032 17.7 3.7 0.0032 17.7 2.6 4.2 3 1 0 4 4 4 1 Protein of unknown function (DUF904) Syntaxin PF00804.20 CCU99786.1 - 0.0056 16.8 14.0 1.3 9.2 0.2 4.0 2 1 1 3 3 3 2 Syntaxin CCDC92 PF14916.1 CCU99786.1 - 0.033 13.7 4.1 0.071 12.7 0.2 2.6 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Cas_GSU0053 PF09617.5 CCU99786.1 - 0.037 13.8 0.4 0.071 12.8 0.3 1.5 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) FlaC_arch PF05377.6 CCU99786.1 - 0.11 12.4 4.9 6.7 6.6 0.0 4.3 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 CCU99786.1 - 0.11 11.6 0.8 0.23 10.6 0.6 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 CCU99786.1 - 0.11 9.7 27.7 0.054 10.8 15.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) IncA PF04156.9 CCU99786.1 - 0.54 9.8 28.0 0.11 12.0 9.2 3.1 2 1 1 3 3 3 0 IncA protein FAD-SLDH PF12318.3 CCU99786.1 - 0.65 9.6 9.3 0.56 9.8 2.5 2.2 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF972 PF06156.8 CCU99786.1 - 0.77 10.1 19.4 4.2 7.7 1.5 3.8 2 1 0 3 3 3 0 Protein of unknown function (DUF972) TBPIP PF07106.8 CCU99786.1 - 0.84 9.1 17.7 0.22 11.0 5.3 3.5 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HALZ PF02183.13 CCU99786.1 - 3.4 7.4 13.4 1.7 8.4 0.2 4.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 CCU99786.1 - 4.3 7.3 16.1 0.21 11.6 0.3 4.6 4 1 1 5 5 5 0 bZIP transcription factor DMPK_coil PF08826.5 CCU99786.1 - 6.1 6.8 26.8 1 9.3 0.2 5.0 3 2 2 5 5 5 0 DMPK coiled coil domain like DASH_Dam1 PF08653.5 CCU99786.1 - 9.9 6.0 6.5 31 4.4 0.0 3.4 4 0 0 4 4 3 0 DASH complex subunit Dam1 CAP_GLY PF01302.20 CCU99787.1 - 1e-09 37.9 0.7 2.1e-09 36.9 0.5 1.5 1 1 0 1 1 1 1 CAP-Gly domain Filament PF00038.16 CCU99787.1 - 0.0047 16.4 11.6 0.0047 16.4 8.0 4.4 2 1 2 4 4 4 3 Intermediate filament protein GN3L_Grn1 PF08701.6 CCU99788.1 - 6.4e-21 74.0 14.8 6.4e-21 74.0 10.2 2.5 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase CENP-T PF15511.1 CCU99788.1 - 8.3e-05 22.0 15.2 8.3e-05 22.0 10.6 2.7 3 0 0 3 3 3 1 Centromere kinetochore component CENP-T DUF1018 PF06252.7 CCU99788.1 - 0.42 11.1 7.6 0.24 11.9 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1018) AAA_17 PF13207.1 CCU99788.1 - 0.54 11.0 8.8 1.8 9.3 0.0 3.1 3 1 0 3 3 3 0 AAA domain BUD22 PF09073.5 CCU99788.1 - 0.57 9.2 43.6 0.013 14.6 19.8 2.4 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.7 CCU99788.1 - 4.3 5.1 50.8 0.024 12.6 25.7 2.2 2 0 0 2 2 2 0 Nop14-like family Proteasome PF00227.21 CCU99789.1 - 6.3e-39 133.2 0.0 8.7e-39 132.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit EF-hand_1 PF00036.27 CCU99790.1 - 8e-22 74.8 14.7 1.9e-07 29.8 0.9 4.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 CCU99790.1 - 1.6e-20 73.0 1.7 4.3e-11 42.7 0.6 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCU99790.1 - 2.1e-18 64.4 7.1 5.1e-05 22.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CCU99790.1 - 5.9e-17 60.1 13.3 4.7e-05 22.5 0.3 4.6 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CCU99790.1 - 1.6e-11 43.6 11.9 0.0029 17.1 0.2 4.0 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CCU99790.1 - 0.00014 21.9 0.1 0.016 15.2 0.0 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CCU99790.1 - 0.0004 20.0 5.3 1 9.1 0.2 3.7 1 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CCU99790.1 - 0.0023 17.8 0.2 4.9 7.1 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain DUF3164 PF11363.3 CCU99790.1 - 0.06 12.7 0.3 0.44 9.9 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3164) DUF465 PF04325.8 CCU99790.1 - 0.23 11.1 1.3 0.54 9.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Ribosomal_S13 PF00416.17 CCU99791.1 - 2.5e-22 79.3 0.0 3.4e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CCU99791.1 - 0.00087 17.9 0.0 0.0012 17.4 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) AMP-binding PF00501.23 CCU99792.1 - 8.4e-53 179.2 0.0 1.3e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Gar1 PF04410.9 CCU99793.1 - 4.2e-41 139.9 0.1 4.2e-41 139.9 0.1 1.9 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region Vps26 PF03643.10 CCU99795.1 - 1e-53 181.8 0.2 1.2e-53 181.7 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Glyco_tranf_2_3 PF13641.1 CCU99796.1 - 8.4e-21 74.8 0.0 1.2e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CCU99796.1 - 9.3e-14 51.5 2.7 4.2e-13 49.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 CCU99796.1 - 1.1e-06 28.0 0.0 1.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CCU99796.1 - 2e-06 27.5 0.0 3.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Topoisom_I_N PF02919.10 CCU99797.1 - 7.2e-73 244.4 0.2 7.2e-73 244.4 0.2 3.4 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CCU99797.1 - 1.5e-61 207.5 0.1 1.5e-61 207.5 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 CCU99797.1 - 2.8e-16 58.9 3.6 3e-13 49.2 0.1 3.4 3 0 0 3 3 3 2 C-terminal topoisomerase domain Sporozoite_P67 PF05642.6 CCU99797.1 - 4.5 5.0 13.2 8.3 4.1 9.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen V_ATPase_I PF01496.14 CCU99797.1 - 6.2 4.5 6.9 12 3.5 4.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAS PF00989.19 CCU99798.1 - 4.7e-05 23.1 0.0 9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 CCU99798.1 - 0.055 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 PAS domain PEPCK_ATP PF01293.15 CCU99799.1 - 1.1e-202 673.7 0.0 9.4e-202 670.6 0.0 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxykinase MPC PF03650.8 CCU99800.1 - 1.2e-32 112.3 0.4 1.4e-32 112.1 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Rod_cone_degen PF15201.1 CCU99800.1 - 0.24 11.2 2.0 0.41 10.5 1.4 1.4 1 0 0 1 1 1 0 Progressive rod-cone degeneration Mg_trans_NIPA PF05653.9 CCU99801.1 - 4.6e-90 301.6 24.3 6.1e-90 301.2 16.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CCU99801.1 - 1.1e-05 25.4 5.8 1.1e-05 25.4 4.0 3.4 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 CCU99801.1 - 2.5e-05 24.4 5.3 2.5e-05 24.4 3.7 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Neurensin PF14927.1 CCU99801.1 - 1.3 8.4 5.1 13 5.1 1.3 2.6 2 0 0 2 2 2 0 Neurensin PP2C PF00481.16 CCU99802.1 - 1.1e-43 149.4 0.0 9e-43 146.4 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 CCU99802.1 - 7.9e-43 143.4 39.7 4.1e-07 29.4 1.1 12.5 4 2 8 13 13 13 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCU99802.1 - 3.3e-40 135.6 44.3 6.5e-09 35.4 0.0 9.6 4 4 4 9 9 9 8 Leucine rich repeat Guanylate_cyc PF00211.15 CCU99802.1 - 6.3e-26 90.8 0.0 1.2e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 CCU99802.1 - 1.5e-24 82.2 37.5 0.21 11.7 0.0 17.5 18 1 1 19 19 19 8 Leucine Rich Repeat LRR_7 PF13504.1 CCU99802.1 - 2.7e-12 44.7 48.0 4.1 8.0 0.5 17.8 18 1 0 18 18 18 4 Leucine rich repeat LRR_6 PF13516.1 CCU99802.1 - 8.8e-06 25.2 30.9 14 6.1 0.0 13.5 13 2 1 14 14 14 1 Leucine Rich repeat LRR_9 PF14580.1 CCU99802.1 - 0.0064 16.0 10.2 3.1 7.3 0.1 4.2 3 1 2 5 5 5 3 Leucine-rich repeat Mito_carr PF00153.22 CCU99803.1 - 7.7e-47 156.9 7.1 9.6e-19 66.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ATP-sulfurylase PF01747.12 CCU99804.1 - 7.9e-86 286.8 0.1 1.1e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 CCU99804.1 - 6e-57 191.6 0.0 8.7e-57 191.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 CCU99804.1 - 2.1e-51 173.5 0.0 3.3e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 CCU99804.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CBFD_NFYB_HMF PF00808.18 CCU99805.1 - 5e-08 32.8 0.1 2.7e-07 30.5 0.1 2.2 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ku PF02735.11 CCU99806.1 - 1.2e-32 112.9 0.0 1.9e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CCU99806.1 - 1.5e-08 34.3 0.0 3.3e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 CCU99806.1 - 0.0005 20.5 0.0 0.0013 19.2 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm adh_short_C2 PF13561.1 CCU99807.1 - 7.8e-27 94.5 0.0 9.6e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCU99807.1 - 1.5e-20 73.7 0.6 1.9e-20 73.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCU99807.1 - 1.1e-10 41.4 0.1 1.6e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CCU99807.1 - 0.047 12.5 0.1 0.068 12.0 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 CCU99807.1 - 0.095 12.7 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L39 PF00832.15 CCU99808.1 - 2.1e-20 71.9 10.0 2.5e-20 71.6 7.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein WD40 PF00400.27 CCU99810.1 - 3.3e-47 156.7 15.9 5.7e-10 38.6 0.1 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat Nbas_N PF15492.1 CCU99810.1 - 9.5e-06 24.9 0.1 0.14 11.2 0.0 3.6 3 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 CCU99810.1 - 1.3e-05 24.7 8.6 0.005 16.3 0.3 3.2 2 1 0 3 3 3 2 PQQ-like domain Nup160 PF11715.3 CCU99810.1 - 0.008 14.3 0.4 0.074 11.1 0.1 2.4 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCU99810.1 - 0.021 13.6 0.0 3.4 6.3 0.0 3.4 3 2 1 4 4 4 0 Nup133 N terminal like TruB_C PF09142.6 CCU99810.1 - 0.063 12.9 2.7 10 5.8 0.6 3.0 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal IKI3 PF04762.7 CCU99810.1 - 0.29 8.9 0.0 27 2.3 0.0 3.1 2 2 2 4 4 4 0 IKI3 family PQQ PF01011.16 CCU99810.1 - 3.5 7.3 6.2 23 4.7 0.5 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat DUF3684 PF12449.3 CCU99811.1 - 0 1068.1 0.0 0 1067.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Diphthamide_syn PF01866.12 CCU99811.1 - 1.1e-57 195.5 0.0 8.8e-32 110.5 0.0 2.3 2 0 0 2 2 2 2 Putative diphthamide synthesis protein TPR_11 PF13414.1 CCU99811.1 - 2e-23 81.7 7.1 7.1e-13 48.0 0.0 4.0 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 CCU99811.1 - 3.5e-19 67.5 3.0 0.00011 21.6 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 CCU99811.1 - 2.3e-14 52.0 6.9 0.0054 16.5 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CCU99811.1 - 2.9e-13 50.0 6.8 0.00012 22.6 0.0 6.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCU99811.1 - 1.3e-11 44.2 7.2 1.2e-06 28.3 0.0 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCU99811.1 - 1.2e-10 40.3 2.5 0.12 12.2 0.0 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCU99811.1 - 7.9e-10 38.4 6.6 0.013 16.0 0.0 7.6 5 2 2 7 7 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCU99811.1 - 1.1e-07 31.5 2.9 0.1 12.8 0.0 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCU99811.1 - 1.5e-07 31.6 3.9 0.0032 17.7 0.4 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCU99811.1 - 1.1e-05 24.8 0.3 0.13 12.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CCU99811.1 - 0.00047 20.2 5.3 0.23 11.6 0.3 3.1 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CCU99811.1 - 0.0072 16.2 5.6 1.3 9.0 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 CCU99811.1 - 0.0087 16.1 16.3 0.1 12.7 0.7 6.0 4 1 1 6 6 5 1 Tetratricopeptide repeat HATPase_c_3 PF13589.1 CCU99811.1 - 0.45 10.1 0.0 0.88 9.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DDE_Tnp_ISL3 PF01610.12 CCU99811.1 - 1 8.9 0.6 2.2 7.7 0.4 1.5 1 0 0 1 1 1 0 Transposase MRC1 PF09444.5 CCU99812.1 - 5.5e-21 75.4 16.6 5.5e-21 75.4 11.5 2.4 2 1 0 2 2 2 2 MRC1-like domain tRNA-synt_1b PF00579.20 CCU99813.1 - 1.1e-22 80.5 0.0 1.3e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Tim17 PF02466.14 CCU99814.1 - 1.2e-29 102.9 3.4 1.4e-29 102.6 2.4 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ATP-synt_DE_N PF02823.11 CCU99815.1 - 2e-19 69.1 0.1 3.1e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ABC_membrane_2 PF06472.10 CCU99816.1 - 1.6e-66 224.3 2.7 2.1e-66 223.9 1.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CCU99816.1 - 7.1e-20 71.6 0.0 1.7e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCU99816.1 - 0.0027 17.7 0.1 0.0091 15.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 CCU99816.1 - 0.0062 15.7 0.0 0.17 11.0 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCU99816.1 - 0.036 13.6 0.0 0.084 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CCU99816.1 - 0.065 13.5 0.2 0.37 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CCU99816.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CCU99816.1 - 0.1 12.0 0.0 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF258 PF03193.11 CCU99816.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SecY PF00344.15 CCU99817.1 - 4.1e-95 318.6 13.7 5.8e-95 318.1 9.5 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CCU99817.1 - 2.5e-17 62.0 0.3 6.5e-17 60.7 0.2 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p ECH_C PF13766.1 CCU99818.1 - 0.36 10.9 2.6 0.74 9.9 0.5 2.4 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region BRE1 PF08647.6 CCU99819.1 - 1.5e-19 69.7 8.5 1.5e-19 69.7 5.9 5.6 5 2 0 5 5 5 1 BRE1 E3 ubiquitin ligase IncA PF04156.9 CCU99819.1 - 0.017 14.7 1.0 0.017 14.7 0.7 5.6 2 1 2 4 4 4 0 IncA protein zf-C3HC4_2 PF13923.1 CCU99819.1 - 0.28 11.2 0.4 0.47 10.5 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ATG16 PF08614.6 CCU99819.1 - 0.54 10.0 67.0 0.13 12.0 10.1 5.1 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 CCU99819.1 - 0.55 8.6 33.7 0.19 10.1 6.7 3.6 3 1 1 4 4 4 0 AAA domain Fez1 PF06818.10 CCU99819.1 - 1.7 8.5 67.7 0.18 11.7 1.7 5.0 1 1 4 6 6 6 0 Fez1 Mnd1 PF03962.10 CCU99819.1 - 9.4 5.8 55.1 0.041 13.5 2.0 5.2 3 2 2 5 5 5 0 Mnd1 family Pyridoxal_deC PF00282.14 CCU99820.1 - 4.4e-24 84.6 0.0 7.6e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CCU99820.1 - 2e-08 33.3 0.0 5.1e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CCU99820.1 - 0.041 12.9 0.6 0.076 12.0 0.1 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family TFIIA PF03153.8 CCU99821.1 - 1.2e-51 176.8 12.0 2.3e-31 110.0 8.6 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 CCU99821.1 - 0.24 11.0 5.2 0.33 10.6 3.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Med26 PF08711.6 CCU99822.1 - 0.00032 20.1 0.0 0.00068 19.0 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF2201_N PF13203.1 CCU99822.1 - 0.017 14.3 6.0 0.023 13.8 4.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain PWWP PF00855.12 CCU99822.1 - 0.048 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 PWWP domain TRAP_alpha PF03896.11 CCU99822.1 - 0.43 9.5 3.2 0.69 8.8 2.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mif2_N PF15624.1 CCU99822.1 - 1.1 9.8 7.6 1.8 9.1 5.2 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DUF4611 PF15387.1 CCU99822.1 - 2.6 8.2 8.3 8 6.6 5.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.9 CCU99822.1 - 6.1 4.7 9.2 7.6 4.4 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Hamartin PF04388.7 CCU99823.1 - 2.1e-17 63.0 0.3 2.1e-17 63.0 0.2 2.4 1 1 1 2 2 2 1 Hamartin protein DUF1315 PF07023.7 CCU99823.1 - 0.023 14.5 0.5 0.07 13.0 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1315) AAA_13 PF13166.1 CCU99823.1 - 0.22 9.9 8.8 0.31 9.4 6.1 1.1 1 0 0 1 1 1 0 AAA domain HALZ PF02183.13 CCU99823.1 - 0.77 9.5 11.6 3 7.6 0.2 3.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4200 PF13863.1 CCU99823.1 - 2 8.3 23.7 0.31 10.9 3.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) EMP70 PF02990.11 CCU99824.1 - 5.4e-175 582.7 0.1 2e-174 580.9 0.0 1.8 2 0 0 2 2 2 1 Endomembrane protein 70 tRNA-synt_1c PF00749.16 CCU99824.1 - 3.4e-101 338.0 0.0 5.3e-101 337.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 CCU99824.1 - 1e-31 109.7 0.0 1.7e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 CCU99824.1 - 8.3e-30 103.7 0.0 6.7e-29 100.7 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 CCU99824.1 - 7e-08 33.0 0.9 7e-08 33.0 0.6 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Clc-like PF07062.7 CCU99824.1 - 1.5 8.0 8.5 1.8 7.7 1.7 2.5 2 0 0 2 2 2 0 Clc-like Sybindin PF04099.7 CCU99825.1 - 4.2e-07 29.7 0.0 6.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family GHMP_kinases_N PF00288.21 CCU99826.1 - 1.4e-06 28.2 1.4 3.4e-06 27.0 1.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Ribosomal_L27e PF01777.13 CCU99827.1 - 2.1e-36 123.9 1.2 2.9e-36 123.4 0.8 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CCU99827.1 - 0.08 12.7 0.8 0.22 11.3 0.6 1.8 1 0 0 1 1 1 0 KOW motif Ribosom_S12_S23 PF00164.20 CCU99828.1 - 4.7e-38 129.3 0.7 5.3e-38 129.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 T4_Gp59_C PF08994.5 CCU99828.1 - 0.042 13.9 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term CBP4 PF07960.6 CCU99829.1 - 7.5e-11 41.7 0.4 2.3e-10 40.2 0.3 1.7 1 1 0 1 1 1 1 CBP4 MitoNEET_N PF10660.4 CCU99829.1 - 0.078 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF4574 PF15141.1 CCU99829.1 - 0.79 9.4 2.5 4.5 7.0 1.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4574) Brix PF04427.13 CCU99830.1 - 2.5e-39 134.9 0.0 3.3e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain Erg28 PF03694.8 CCU99831.1 - 5.4e-34 116.5 0.3 6.2e-34 116.3 0.2 1.0 1 0 0 1 1 1 1 Erg28 like protein DUF308 PF03729.8 CCU99831.1 - 0.28 11.1 2.9 3.1 7.8 0.2 2.5 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) YiaAB PF05360.9 CCU99831.1 - 3.9 7.1 7.2 8.1 6.0 0.0 3.4 4 0 0 4 4 4 0 yiaA/B two helix domain GST_N_2 PF13409.1 CCU99832.1 - 1e-15 57.4 0.0 2.4e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCU99832.1 - 1.2e-15 57.0 0.1 2.3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCU99832.1 - 4.9e-07 29.6 0.0 8.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCU99832.1 - 0.00017 21.7 0.0 0.87 9.8 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCU99832.1 - 0.00041 20.7 0.0 0.00075 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain POT1 PF02765.12 CCU99833.1 - 0.0016 18.4 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Rpr2 PF04032.11 CCU99833.1 - 0.059 13.2 0.3 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain tRNA-synt_2 PF00152.15 CCU99834.1 - 3.5e-87 292.3 0.0 4.5e-87 291.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCU99834.1 - 2.8e-11 43.0 0.0 6.4e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCU99834.1 - 2.5e-08 33.4 0.0 4e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CCU99834.1 - 0.034 13.7 0.0 9.3 5.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) zf-CCCH PF00642.19 CCU99836.1 - 3.6e-09 36.0 2.5 8.3e-09 34.9 1.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 CCU99836.1 - 8e-08 32.1 9.4 1.4e-07 31.4 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCU99836.1 - 8.7e-08 31.7 4.5 1.4e-07 31.0 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCU99836.1 - 6.5e-06 25.7 8.5 1.1e-05 25.0 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCU99836.1 - 8e-05 22.3 7.8 0.00013 21.6 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 CCU99836.1 - 0.00022 21.0 7.5 0.00046 20.0 5.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CCU99836.1 - 0.00062 19.3 9.2 0.0011 18.5 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CCU99836.1 - 0.0058 16.1 2.5 0.01 15.3 1.7 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CCU99836.1 - 0.0095 15.6 5.4 0.02 14.6 3.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RanBP PF00641.13 CCU99836.1 - 0.11 11.6 0.2 0.24 10.5 0.1 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others GATase_5 PF13507.1 CCU99837.1 - 2.7e-89 298.4 0.0 4.3e-89 297.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 CCU99837.1 - 5.5e-48 162.8 0.5 6e-26 91.2 0.0 2.6 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CCU99837.1 - 1.2e-22 79.9 0.7 5.3e-22 77.8 0.1 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain SWIRM PF04433.12 CCU99838.1 - 3.4e-09 36.6 0.0 8.6e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 CCU99838.1 - 3.7e-09 35.9 7.1 6.7e-09 35.1 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 CCU99838.1 - 1e-06 28.7 0.0 4.4e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCU99838.1 - 0.0028 17.7 0.0 0.0084 16.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-CCCH PF00642.19 CCU99839.1 - 4.6e-13 48.4 13.2 1.7e-06 27.5 2.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 CCU99839.1 - 5.2e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCU99839.1 - 0.0007 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 CCU99840.1 - 3.2e-43 146.9 0.0 4e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU99840.1 - 1.1e-18 67.8 0.0 1.4e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCU99840.1 - 2.3e-11 43.2 0.0 2.5e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCU99840.1 - 2.4e-06 27.5 0.0 4.1e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCU99840.1 - 0.00094 18.6 0.0 0.0094 15.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCU99840.1 - 0.0095 15.7 0.0 0.018 14.8 0.0 1.6 1 1 0 1 1 1 1 Dynamin family SRPRB PF09439.5 CCU99840.1 - 0.024 13.8 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CCU99840.1 - 0.069 12.2 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Choline_sulf_C PF12411.3 CCU99840.1 - 0.12 12.2 0.5 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal MFS_1 PF07690.11 CCU99841.1 - 4.8e-34 117.6 45.7 5e-29 101.1 18.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCU99841.1 - 2.2e-29 102.3 19.8 3.8e-19 68.6 4.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 CCU99841.1 - 0.013 15.2 3.9 0.17 11.6 0.0 3.1 2 1 1 3 3 3 0 MFS_1 like family DUF1604 PF07713.8 CCU99841.1 - 0.19 11.5 0.3 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) zf-DHHC PF01529.15 CCU99842.1 - 3.1e-32 111.3 6.4 3.8e-31 107.8 4.4 2.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase zf-SNAP50_C PF12251.3 CCU99843.1 - 3.1e-13 49.5 0.1 8e-13 48.2 0.0 1.8 2 1 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal Sulfatase_C PF14707.1 CCU99843.1 - 0.14 12.4 0.2 0.48 10.7 0.0 1.9 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase PI3_PI4_kinase PF00454.22 CCU99844.1 - 5.3e-27 94.8 0.0 8.3e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ATP11 PF06644.6 CCU99845.1 - 7.7e-72 241.9 5.4 9e-72 241.7 3.7 1.0 1 0 0 1 1 1 1 ATP11 protein CAF-1_p150 PF11600.3 CCU99845.1 - 0.0063 15.9 15.3 0.012 14.9 10.6 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal OmpH PF03938.9 CCU99845.1 - 0.021 14.7 11.1 0.051 13.5 7.7 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GrpE PF01025.14 CCU99845.1 - 0.31 10.5 9.4 0.14 11.7 1.9 2.2 1 1 1 2 2 2 0 GrpE GWT1 PF06423.7 CCU99847.1 - 0.035 14.1 0.6 0.18 11.8 0.0 2.6 2 0 0 2 2 2 0 GWT1 OSCP PF00213.13 CCU99848.1 - 6.7e-34 117.2 0.7 7.9e-34 116.9 0.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit eIF-3c_N PF05470.7 CCU99849.1 - 1.7e-167 558.1 10.0 1.7e-167 558.1 7.0 2.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CCU99849.1 - 1.3e-12 47.9 0.1 8.7e-12 45.2 0.0 2.5 2 1 0 2 2 2 1 PCI domain adh_short_C2 PF13561.1 CCU99849.1 - 0.02 14.6 0.1 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase CDC45 PF02724.9 CCU99849.1 - 1 7.3 13.8 2.1 6.2 9.6 1.5 1 0 0 1 1 1 0 CDC45-like protein Dfp1_Him1_M PF08630.5 CCU99850.1 - 8.3e-28 96.6 0.0 1.6e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 CCU99850.1 - 2.5e-18 65.4 2.4 4.5e-18 64.6 1.7 1.4 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 CCU99850.1 - 0.0051 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCU99850.1 - 0.02 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain RNase_H PF00075.19 CCU99851.1 - 1.3e-27 96.7 0.0 1.7e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 CCU99851.1 - 4.6e-16 58.5 0.1 8.4e-16 57.7 0.1 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF218 PF02698.12 CCU99852.1 - 5.9e-18 64.8 0.0 8.3e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain FAD_binding_1 PF00667.15 CCU99853.1 - 4.6e-52 176.6 0.0 8e-52 175.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCU99853.1 - 3.5e-30 104.8 0.1 8.7e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCU99853.1 - 9.1e-20 71.2 0.0 2.3e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 CCU99853.1 - 0.081 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Rad10 PF03834.9 CCU99854.1 - 1e-30 105.2 0.1 1.7e-30 104.5 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 CCU99854.1 - 1e-07 31.9 0.0 2.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain UIM PF02809.15 CCU99854.1 - 0.0012 18.2 3.4 0.0016 17.8 1.4 2.0 2 0 0 2 2 2 1 Ubiquitin interaction motif HHH_2 PF12826.2 CCU99854.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ribosomal_S8e PF01201.17 CCU99855.1 - 1.6e-37 128.5 7.9 1e-36 126.0 5.5 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 CCU99855.1 - 0.019 14.8 0.5 0.05 13.5 0.0 1.7 2 0 0 2 2 2 0 Mer2 Macoilin PF09726.4 CCU99855.1 - 0.79 7.9 10.6 1.1 7.5 7.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Yip1 PF04893.12 CCU99856.1 - 6e-09 35.6 7.6 8.3e-09 35.1 5.3 1.3 1 0 0 1 1 1 1 Yip1 domain DUF2964 PF11177.3 CCU99856.1 - 0.31 10.9 1.8 0.61 10.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) DNA_mis_repair PF01119.14 CCU99857.1 - 1.5e-32 111.5 0.0 2.5e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CCU99857.1 - 1.9e-13 50.2 0.0 4.7e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCU99857.1 - 3.2e-10 39.7 0.1 8.5e-10 38.3 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RNase_PH PF01138.16 CCU99859.1 - 2.7e-14 53.5 0.0 6.2e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCU99859.1 - 7.4e-05 22.6 0.0 0.0002 21.1 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PTPA PF03095.10 CCU99861.1 - 1.7e-107 359.0 0.0 2.1e-107 358.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein WD40 PF00400.27 CCU99862.1 - 1.8e-16 59.3 0.1 0.00028 20.6 0.0 5.2 6 0 0 6 6 6 4 WD domain, G-beta repeat LisH PF08513.6 CCU99862.1 - 0.003 17.2 0.0 0.0076 15.9 0.0 1.7 1 0 0 1 1 1 1 LisH Cytochrom_D1 PF02239.11 CCU99862.1 - 0.15 10.3 0.1 0.26 9.5 0.1 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain RabGAP-TBC PF00566.13 CCU99863.1 - 5.9e-41 140.2 0.1 1.4e-40 139.0 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.20 CCU99864.1 - 4.7e-63 212.7 0.0 6.7e-63 212.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99864.1 - 4.1e-36 124.3 0.0 1e-35 123.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU99864.1 - 7.2e-05 21.8 0.1 0.00021 20.3 0.0 1.8 1 1 1 2 2 2 1 Kinase-like GAGA_bind PF06217.7 CCU99864.1 - 0.21 11.5 3.8 0.48 10.3 2.6 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1674 PF07896.7 CCU99865.1 - 2.7e-13 49.8 1.7 4.4e-13 49.2 1.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) P53_TAD PF08563.6 CCU99866.1 - 3.4 6.8 9.3 6.2 5.9 3.5 2.5 2 0 0 2 2 2 0 P53 transactivation motif CI-B14_5a PF07347.7 CCU99867.1 - 0.051 13.3 0.5 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Oxysterol_BP PF01237.13 CCU99868.1 - 3.3e-119 397.5 0.0 5.2e-119 396.8 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.1 CCU99868.1 - 9e-17 60.7 0.1 1.1e-05 25.5 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCU99868.1 - 2e-14 53.6 0.7 4.6e-09 36.5 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCU99868.1 - 7.6e-14 50.7 1.1 2.1e-06 27.2 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 CCU99868.1 - 3e-13 48.5 0.9 0.00011 22.0 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CCU99868.1 - 3.8e-10 39.9 0.0 7.9e-07 29.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH_11 PF15413.1 CCU99868.1 - 7.8e-07 29.3 0.8 3.6e-06 27.1 0.6 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CCU99868.1 - 2.5e-06 27.6 0.0 7.5e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 CCU99868.1 - 7.3e-05 22.7 1.0 0.00019 21.4 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain ABA_GPCR PF12430.3 CCU99869.1 - 2e-33 115.1 3.4 2.7e-33 114.7 2.4 1.2 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CCU99869.1 - 1.7e-07 31.1 0.4 3.9e-07 30.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) FSH1 PF03959.8 CCU99871.1 - 6.6e-38 130.2 0.0 7.7e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 CCU99871.1 - 0.0015 18.5 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCU99871.1 - 0.0041 16.8 0.0 0.0083 15.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 CCU99871.1 - 0.025 14.2 0.0 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal UBA PF00627.26 CCU99872.1 - 1.7e-18 65.8 0.3 5.8e-10 38.7 0.0 3.1 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.6 CCU99872.1 - 3e-16 58.6 4.3 3e-16 58.6 3.0 2.1 2 0 0 2 2 2 1 XPC-binding domain UBA_4 PF14555.1 CCU99872.1 - 0.0054 16.2 0.0 0.024 14.1 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain CARD PF00619.16 CCU99872.1 - 0.052 13.3 0.1 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Caspase recruitment domain CSTF2_hinge PF14327.1 CCU99872.1 - 1 9.5 4.8 5.1 7.2 3.3 2.2 1 1 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 HpaP PF09483.5 CCU99872.1 - 1.3 8.9 11.0 1.4 8.8 7.1 1.5 1 1 0 1 1 1 0 Type III secretion protein (HpaP) CPSase_sm_chain PF00988.17 CCU99874.1 - 5.4e-45 152.0 0.0 8.1e-45 151.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CCU99874.1 - 1.1e-35 122.8 0.0 1.5e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCU99874.1 - 0.00012 21.6 0.6 0.0015 18.0 0.4 2.4 1 1 0 1 1 1 1 Peptidase C26 zf-met PF12874.2 CCU99875.1 - 4e-06 26.8 1.0 7.5e-06 25.9 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCU99875.1 - 0.00023 21.2 0.4 0.00043 20.3 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding BLVR PF06375.6 CCU99875.1 - 0.0084 15.9 0.5 0.013 15.2 0.3 1.3 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) zf-U1 PF06220.7 CCU99875.1 - 0.079 12.5 0.3 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 U1 zinc finger tRNA-synt_1 PF00133.17 CCU99876.1 - 2.6e-229 762.2 0.0 3.6e-229 761.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCU99876.1 - 5.9e-24 84.5 0.0 1.2e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCU99876.1 - 4.4e-19 68.4 0.6 7e-07 28.2 0.3 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CCU99876.1 - 0.0014 17.8 0.0 0.0093 15.1 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain ATP-synt PF00231.14 CCU99877.1 - 2.6e-68 230.5 2.9 3e-68 230.3 2.0 1.0 1 0 0 1 1 1 1 ATP synthase eIF-5_eIF-2B PF01873.12 CCU99878.1 - 2.4e-46 156.4 0.6 3.6e-46 155.8 0.4 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 CCU99878.1 - 0.008 15.4 0.1 0.016 14.5 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Arc_trans_TRASH PF08394.5 CCU99878.1 - 1 9.5 5.9 1.2 9.3 0.1 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain DUF1754 PF08555.5 CCU99878.1 - 4.3 7.9 16.5 3.9 8.1 4.6 2.4 1 1 1 2 2 2 0 Eukaryotic family of unknown function (DUF1754) SAP PF02037.22 CCU99880.1 - 9.1e-13 47.3 0.4 2.5e-12 45.9 0.3 1.8 1 0 0 1 1 1 1 SAP domain Tmemb_cc2 PF10267.4 CCU99880.1 - 0.02 13.4 0.9 0.026 13.1 0.6 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CCT_2 PF09425.5 CCU99880.1 - 0.037 13.5 0.2 0.037 13.5 0.1 3.0 3 0 0 3 3 3 0 Divergent CCT motif HeH PF12949.2 CCU99880.1 - 0.055 13.0 0.3 0.055 13.0 0.2 2.5 3 1 0 3 3 3 0 HeH/LEM domain Packaging_FI PF14000.1 CCU99880.1 - 0.23 11.6 2.6 0.17 12.0 0.6 1.7 1 1 1 2 2 2 0 DNA packaging protein FI ADH_zinc_N PF00107.21 CCU99881.1 - 4.7e-28 97.3 0.3 1e-27 96.2 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCU99881.1 - 1.4e-27 95.6 0.8 1.4e-27 95.6 0.6 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 CCU99881.1 - 3.1e-06 26.7 0.1 7e-06 25.5 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Methyltransf_25 PF13649.1 CCU99881.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.1 CCU99881.1 - 0.026 14.5 0.1 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CCU99881.1 - 0.063 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_11 PF08241.7 CCU99881.1 - 0.075 13.5 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 CCU99881.1 - 0.11 11.8 0.2 0.24 10.7 0.1 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SPC25 PF06703.6 CCU99882.1 - 3.7e-08 33.1 0.0 0.002 17.7 0.0 2.4 2 1 0 2 2 2 2 Microsomal signal peptidase 25 kDa subunit (SPC25) W2 PF02020.13 CCU99883.1 - 9e-18 64.0 0.0 2.9e-17 62.3 0.0 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon SNF2_N PF00176.18 CCU99884.1 - 9.1e-55 185.5 0.1 1.2e-54 185.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCU99884.1 - 2.9e-14 52.6 0.0 6.2e-13 48.4 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCU99884.1 - 0.0012 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CCU99884.1 - 0.0019 17.0 0.0 0.23 10.2 0.0 2.7 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 EBP PF05241.7 CCU99885.1 - 2.9e-28 98.1 6.3 3.8e-28 97.8 4.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2644 PF10841.3 CCU99885.1 - 0.055 13.4 0.4 0.055 13.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) HXXEE PF13787.1 CCU99885.1 - 0.32 11.3 4.1 0.085 13.2 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif DUF2431 PF10354.4 CCU99888.1 - 1.1e-27 97.0 0.0 6.3e-25 88.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) DnaJ PF00226.26 CCU99889.1 - 1.5e-22 79.0 0.4 1.5e-22 79.0 0.3 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 CCU99889.1 - 3e-19 68.4 17.4 4e-12 45.6 0.9 5.4 5 0 0 5 5 5 3 TPR repeat TPR_16 PF13432.1 CCU99889.1 - 7.3e-15 55.1 30.2 2.9e-06 27.8 3.7 5.5 5 1 2 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCU99889.1 - 2.8e-14 53.2 24.1 0.00022 21.5 1.1 5.9 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 CCU99889.1 - 8.3e-14 50.3 20.8 0.0012 18.6 0.1 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 CCU99889.1 - 2.3e-13 49.0 15.4 0.011 15.2 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 CCU99889.1 - 7.8e-12 44.8 19.9 1.2e-07 31.4 1.7 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCU99889.1 - 3.9e-11 42.2 5.8 0.003 17.6 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCU99889.1 - 4.3e-10 39.3 26.8 0.14 12.8 0.7 8.5 5 3 4 9 9 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 CCU99889.1 - 0.0002 20.9 7.9 2.5 8.0 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCU99889.1 - 0.00085 18.9 16.9 0.94 9.4 0.2 6.4 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 CCU99889.1 - 0.00098 19.1 16.5 0.11 12.6 0.1 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.12 CCU99889.1 - 0.0017 18.6 11.3 0.11 12.7 1.0 3.7 2 1 1 3 3 3 2 Bacterial transcriptional activator domain TPR_6 PF13174.1 CCU99889.1 - 0.017 15.5 23.0 0.58 10.7 0.1 8.4 8 1 0 8 8 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCU99889.1 - 0.14 12.1 18.6 0.38 10.7 1.7 5.0 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 CCU99889.1 - 4.3 8.0 11.8 32 5.3 0.5 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Bax1-I PF01027.15 CCU99890.1 - 6.1e-43 146.8 25.8 7.3e-43 146.5 17.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3392 PF11872.3 CCU99890.1 - 0.79 9.7 7.5 0.56 10.1 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) DUF4044 PF13253.1 CCU99890.1 - 3.8 6.7 5.8 1.1 8.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) DUF4131 PF13567.1 CCU99890.1 - 4.4 6.6 14.3 1.8 7.9 1.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) PIGA PF08288.7 CCU99891.1 - 5e-40 135.7 0.7 8.4e-39 131.8 0.1 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CCU99891.1 - 1.1e-25 90.0 0.0 1.7e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CCU99891.1 - 7.3e-11 42.3 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CCU99891.1 - 1.1e-06 28.5 0.1 2.6e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.1 CCU99891.1 - 0.0044 16.8 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 CCU99891.1 - 0.016 15.4 0.0 0.054 13.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 DUF2428 PF10350.4 CCU99892.1 - 1.5e-46 158.5 1.2 3e-46 157.5 0.8 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 CCU99892.1 - 0.00036 20.3 23.0 0.019 15.0 0.2 7.4 8 0 0 8 8 8 3 HEAT repeat Adaptin_N PF01602.15 CCU99892.1 - 0.17 10.2 0.4 0.61 8.3 0.1 2.0 2 0 0 2 2 2 0 Adaptin N terminal region DNA_pol_E_B PF04042.11 CCU99893.1 - 1.4e-42 145.3 0.0 2e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.3 CCU99893.1 - 0.0037 17.1 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal Septin PF00735.13 CCU99895.1 - 3.4e-108 360.9 0.8 4.9e-108 360.4 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CCU99895.1 - 1e-07 31.9 0.0 2.8e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCU99895.1 - 1.9e-05 24.5 1.8 0.014 15.2 0.0 3.1 3 0 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 CCU99895.1 - 2e-05 24.0 0.0 0.00023 20.6 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CCU99895.1 - 2.4e-05 23.5 0.2 0.0001 21.5 0.1 2.0 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Ras PF00071.17 CCU99895.1 - 9.8e-05 21.7 0.3 0.00039 19.8 0.0 2.0 2 0 0 2 2 2 1 Ras family AIG1 PF04548.11 CCU99895.1 - 0.00042 19.5 0.5 0.00091 18.3 0.0 1.9 2 0 0 2 2 2 1 AIG1 family AAA_10 PF12846.2 CCU99895.1 - 0.0028 17.1 0.1 0.012 15.1 0.0 2.0 2 1 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 CCU99895.1 - 0.0045 17.1 0.5 0.016 15.3 0.0 2.2 2 2 0 2 2 2 1 AAA domain Strep_SA_rep PF06696.6 CCU99895.1 - 0.0079 15.9 5.3 0.015 15.0 0.0 2.6 2 0 0 2 2 2 1 Streptococcal surface antigen repeat AAA_16 PF13191.1 CCU99895.1 - 0.0085 16.0 1.6 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 CCU99895.1 - 0.017 15.4 0.3 0.017 15.4 0.2 2.4 2 2 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 CCU99895.1 - 0.029 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 CCU99895.1 - 0.032 14.7 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 CCU99895.1 - 0.078 12.6 0.2 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_P4 PF11602.3 CCU99895.1 - 0.08 11.9 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Gtr1_RagA PF04670.7 CCU99895.1 - 0.1 11.7 0.0 0.31 10.1 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 CCU99895.1 - 0.11 12.0 0.1 8.9 5.7 0.0 2.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.10 CCU99895.1 - 0.12 11.5 8.2 0.22 10.6 5.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3457 PF11939.3 CCU99895.1 - 0.14 11.6 1.9 0.24 10.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3457) IIGP PF05049.8 CCU99895.1 - 0.14 10.9 1.2 0.22 10.2 0.0 1.9 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 CCU99895.1 - 0.38 10.2 0.0 0.38 10.2 0.0 2.9 2 1 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 CCU99895.1 - 1.1 9.0 0.0 1.1 9.0 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF87 YlqD PF11068.3 CCU99895.1 - 6.1 6.8 9.8 13 5.8 6.8 1.6 1 0 0 1 1 1 0 YlqD protein LRR_9 PF14580.1 CCU99896.1 - 9.3e-47 158.8 0.7 1.3e-46 158.3 0.5 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CCU99896.1 - 5.6e-16 57.7 10.3 1.3e-07 31.0 1.0 4.3 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCU99896.1 - 6e-10 38.7 21.4 5.5e-06 26.0 3.1 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 CCU99896.1 - 0.00022 20.9 1.5 6 7.2 0.0 4.5 4 1 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 CCU99896.1 - 0.0059 16.4 8.5 7.3 7.0 0.3 5.2 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 CCU99896.1 - 0.35 11.2 8.4 8.6 7.0 0.0 4.7 4 2 1 5 5 5 0 Leucine rich repeat Dynein_heavy PF03028.10 CCU99897.1 - 1.6e-103 347.1 0.0 5.6e-103 345.3 0.0 1.7 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 CCU99897.1 - 2.3e-39 135.1 2.3 4.4e-39 134.2 1.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CCU99897.1 - 1.2e-35 122.4 0.0 4.1e-35 120.6 0.0 1.8 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 Spc97_Spc98 PF04130.8 CCU99897.1 - 0.08 11.2 0.3 1.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Spc97 / Spc98 family Caps_synth_GfcC PF06251.6 CCU99897.1 - 0.31 10.1 15.9 0.76 8.8 0.3 2.7 2 0 0 2 2 2 0 Capsule biosynthesis GfcC V_ATPase_I PF01496.14 CCU99897.1 - 0.49 8.1 5.9 0.85 7.3 4.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 CCU99897.1 - 0.69 8.5 19.8 0.89 8.1 5.7 3.1 3 0 0 3 3 3 0 Spc7 kinetochore protein ERM PF00769.14 CCU99897.1 - 2.9 7.3 30.0 0.55 9.7 9.4 3.1 3 0 0 3 3 3 0 Ezrin/radixin/moesin family CBFB_NFYA PF02045.10 CCU99898.1 - 1.2e-29 102.6 2.8 2.9e-29 101.3 1.9 1.7 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF1162 PF06650.7 CCU99899.1 - 1.4e-54 185.1 0.0 3e-52 177.5 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CCU99899.1 - 3.7e-38 129.6 0.1 1e-37 128.2 0.1 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 CCU99899.1 - 0.00032 20.7 0.0 0.00091 19.3 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain DUF756 PF05506.7 CCU99899.1 - 0.0069 16.8 0.0 0.87 10.1 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF756) MRP-L47 PF06984.8 CCU99900.1 - 1.4e-18 66.5 1.2 2.2e-18 65.9 0.8 1.4 1 1 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 CCU99900.1 - 0.0092 15.6 0.2 0.11 12.2 0.1 2.3 2 0 0 2 2 2 1 Ribosomal L29 protein Nramp PF01566.13 CCU99901.1 - 2e-88 296.5 17.9 4.5e-88 295.4 12.4 1.5 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein ketoacyl-synt PF00109.21 CCU99902.1 - 2.5e-64 217.2 0.1 6.6e-64 215.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.7 CCU99902.1 - 1.3e-46 158.5 0.0 2.4e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 CCU99902.1 - 2.3e-44 152.0 1.4 3.4e-44 151.4 0.0 2.0 3 0 0 3 3 3 1 Acyl transferase domain KR PF08659.5 CCU99902.1 - 2.2e-35 121.9 0.1 8.5e-34 116.7 0.0 2.7 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.17 CCU99902.1 - 8.8e-34 115.9 0.2 2.1e-32 111.4 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 CCU99902.1 - 7.5e-31 107.2 1.7 2.9e-29 102.1 0.0 3.1 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 CCU99902.1 - 2.3e-25 89.3 0.0 4.3e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Epimerase PF01370.16 CCU99902.1 - 2.3e-15 56.6 0.0 6.8e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 CCU99902.1 - 1.1e-10 41.1 0.0 4.6e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CCU99902.1 - 2.8e-09 37.2 0.5 1.2e-05 25.3 0.2 4.1 3 1 0 3 3 3 1 NADH(P)-binding PP-binding PF00550.20 CCU99902.1 - 0.00018 21.6 0.5 0.00049 20.3 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 CCU99902.1 - 0.00029 20.6 0.0 0.0008 19.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 CCU99902.1 - 0.00054 19.6 0.1 0.0029 17.3 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CCU99902.1 - 0.00098 20.0 0.0 0.0085 16.9 0.0 2.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 CCU99902.1 - 0.0025 18.2 0.0 0.0073 16.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 CCU99902.1 - 0.011 14.3 0.0 0.052 12.2 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CCU99902.1 - 0.018 14.3 0.1 0.041 13.1 0.1 1.6 1 0 0 1 1 1 0 NmrA-like family Methyltransf_31 PF13847.1 CCU99902.1 - 0.033 13.7 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain ELFV_dehydrog PF00208.16 CCU99902.1 - 0.078 12.5 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Methyltransf_11 PF08241.7 CCU99902.1 - 0.091 13.2 0.0 0.33 11.4 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain ThiF PF00899.16 CCU99902.1 - 0.096 12.5 0.2 0.25 11.1 0.2 1.7 1 0 0 1 1 1 0 ThiF family Nup96 PF12110.3 CCU99903.1 - 2.1e-79 266.6 2.7 3.6e-79 265.9 1.9 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 CCU99903.1 - 1.8e-40 137.9 0.0 3.9e-40 136.9 0.0 1.6 1 1 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CCU99903.1 - 8.4e-26 90.4 339.6 6.5e-09 36.0 30.5 9.3 3 2 7 10 10 10 8 Nucleoporin FG repeat region DUF2600 PF10776.4 CCU99903.1 - 1.4 7.6 0.2 2.3 7.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) HSCB_C PF07743.8 CCU99904.1 - 4.3e-14 52.7 6.9 7.7e-14 51.9 4.8 1.4 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 CCU99904.1 - 8.4e-11 41.4 0.2 4.3e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain DZR PF12773.2 CCU99904.1 - 0.017 14.9 1.2 0.032 14.0 0.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-tcix PF14952.1 CCU99904.1 - 0.033 13.5 3.9 0.06 12.6 2.7 1.3 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding FlaF PF07309.6 CCU99904.1 - 0.2 11.4 1.9 0.36 10.7 1.3 1.4 1 0 0 1 1 1 0 Flagellar protein FlaF SpoIIE PF07228.7 CCU99905.1 - 8.2e-13 48.4 0.0 6.6e-12 45.5 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CCU99905.1 - 1.3e-07 31.2 0.0 2.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CCU99905.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DUF4110 PF13422.1 CCU99906.1 - 5e-13 48.7 0.0 5e-13 48.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 CCU99906.1 - 1.4e-07 31.4 0.1 0.0032 17.5 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 CCU99906.1 - 1.4e-07 31.4 0.3 0.012 15.7 0.0 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.1 CCU99906.1 - 2e-06 27.4 6.0 0.033 13.9 0.1 4.2 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 CCU99906.1 - 0.0051 16.5 0.0 0.3 10.9 0.1 2.9 3 1 0 3 3 3 1 Kelch motif S-antigen PF05756.6 CCU99906.1 - 0.026 14.4 1.2 0.026 14.4 0.8 2.7 1 1 1 2 2 2 0 S-antigen protein Kelch_1 PF01344.20 CCU99906.1 - 0.11 12.0 0.1 0.93 9.0 0.0 2.5 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 CCU99906.1 - 0.14 12.1 0.5 10 6.2 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Daxx PF03344.10 CCU99906.1 - 0.18 10.2 11.0 0.25 9.7 7.6 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 CCU99906.1 - 0.59 7.9 7.4 0.67 7.8 5.1 1.1 1 0 0 1 1 1 0 Nop14-like family Dicty_REP PF05086.7 CCU99906.1 - 0.86 7.2 3.3 1.2 6.8 2.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FAM176 PF14851.1 CCU99906.1 - 3.8 7.1 5.6 6.9 6.3 3.1 1.9 2 0 0 2 2 2 0 FAM176 family COPIIcoated_ERV PF07970.7 CCU99907.1 - 7.6e-30 104.1 0.3 6.7e-28 97.8 0.0 2.6 1 1 1 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCU99907.1 - 1.1e-13 50.9 0.2 2.2e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) LSM PF01423.17 CCU99908.1 - 2.2e-14 52.7 0.1 3.3e-13 48.9 0.1 2.1 1 1 0 1 1 1 1 LSM domain WD40 PF00400.27 CCU99909.1 - 4.3e-10 39.0 1.7 0.44 10.4 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Ctr PF04145.10 CCU99910.1 - 1.2e-19 70.7 0.1 1.7e-19 70.2 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Med3 PF11593.3 CCU99910.1 - 0.81 8.8 7.6 1.1 8.3 5.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WD40 PF00400.27 CCU99911.1 - 2.7e-50 166.5 24.5 6.1e-12 44.9 0.1 8.9 9 0 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.2 CCU99911.1 - 4.1e-08 32.8 1.1 1.1e-07 31.3 0.8 1.9 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CCU99911.1 - 9e-07 27.4 7.7 0.056 11.5 0.1 4.8 2 1 3 5 5 5 3 Nucleoporin Nup120/160 F-box PF00646.28 CCU99911.1 - 1.5e-05 24.5 0.1 3.2e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 CCU99911.1 - 0.0027 17.8 2.2 9.9 6.5 0.0 5.7 6 0 0 6 6 6 1 PQQ-like domain TPR_11 PF13414.1 CCU99912.1 - 4.6e-36 122.2 18.0 7.4e-17 60.7 1.9 4.6 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 CCU99912.1 - 1.4e-23 81.4 9.8 5.2e-05 22.6 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat DnaJ PF00226.26 CCU99912.1 - 5.7e-23 80.4 1.3 2.2e-22 78.5 0.2 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 CCU99912.1 - 1.1e-22 78.0 19.8 0.00046 19.8 0.0 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 CCU99912.1 - 3.2e-16 59.5 26.6 0.03 14.9 0.0 6.6 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.1 CCU99912.1 - 5.8e-13 48.9 23.2 2.2e-07 31.0 0.8 5.8 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCU99912.1 - 2.7e-12 46.1 25.9 0.0063 17.0 0.4 7.6 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCU99912.1 - 5.2e-09 35.9 18.6 8.8e-05 22.3 0.1 5.8 3 3 2 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 CCU99912.1 - 9.5e-08 32.0 2.4 0.1 12.7 0.2 3.9 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCU99912.1 - 3.5e-05 23.2 4.4 1.8 8.5 0.0 6.2 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCU99912.1 - 3.8e-05 23.1 17.5 0.83 9.6 0.0 6.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCU99912.1 - 0.00097 19.1 9.3 12 6.3 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 CCU99912.1 - 0.0023 17.1 10.6 0.15 11.3 0.1 5.0 5 0 0 5 5 5 1 SHNi-TPR TPR_9 PF13371.1 CCU99912.1 - 0.0064 16.3 28.2 0.16 11.8 0.3 6.5 4 3 3 7 7 7 4 Tetratricopeptide repeat DUF3856 PF12968.2 CCU99912.1 - 0.11 12.3 11.4 0.52 10.1 0.6 4.1 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 CCU99912.1 - 1.5 9.4 21.7 8.7 7.0 0.1 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat PseudoU_synth_1 PF01416.15 CCU99913.1 - 1.3e-20 73.7 0.0 4e-09 36.8 0.0 2.8 3 0 0 3 3 3 2 tRNA pseudouridine synthase Plus-3 PF03126.13 CCU99914.1 - 4.3e-18 65.3 0.0 1.2e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 Plus-3 domain Actin PF00022.14 CCU99915.1 - 1.1e-94 317.0 0.0 1.8e-94 316.3 0.0 1.3 1 1 0 1 1 1 1 Actin Pirin PF02678.11 CCU99916.1 - 4.4e-28 97.2 0.4 1.6e-27 95.4 0.1 2.0 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 CCU99916.1 - 8.3e-25 86.8 0.0 2.8e-24 85.1 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 CCU99916.1 - 0.001 18.5 2.8 0.0039 16.6 1.0 2.5 3 0 0 3 3 3 1 Cupin domain ABC1 PF03109.11 CCU99917.1 - 5.9e-31 106.9 0.0 1e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Oxidored-like PF09791.4 CCU99917.1 - 6.3e-17 60.7 0.5 1.5e-16 59.5 0.4 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Na_trans_assoc PF06512.8 CCU99917.1 - 0.027 14.4 0.1 0.044 13.7 0.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated COX5A PF02284.11 CCU99918.1 - 1.3e-39 134.5 0.2 1.5e-39 134.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va SNF2_N PF00176.18 CCU99919.1 - 1.1e-42 145.8 0.0 1.8e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 CCU99919.1 - 4.8e-06 26.3 15.5 9.8e-06 25.3 10.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCU99919.1 - 1.9e-05 24.2 11.7 3.6e-05 23.3 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCU99919.1 - 0.00011 21.7 15.0 0.00019 21.0 10.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCU99919.1 - 0.00023 21.1 13.8 0.00045 20.1 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCU99919.1 - 0.00029 20.4 13.3 0.00052 19.6 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 CCU99919.1 - 0.0003 20.5 0.0 0.0024 17.7 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.1 CCU99919.1 - 0.0027 17.1 10.2 0.0064 16.0 7.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-UDP PF14569.1 CCU99919.1 - 0.025 14.3 2.5 0.062 13.0 1.8 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.1 CCU99919.1 - 0.063 12.8 9.0 0.12 11.9 6.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 CCU99919.1 - 0.14 12.0 6.6 0.31 10.8 4.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.6 CCU99919.1 - 0.2 11.4 5.2 0.29 10.8 2.8 1.8 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 CCU99919.1 - 1.7 8.5 10.7 3 7.7 7.4 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Myb_DNA-bind_6 PF13921.1 CCU99921.1 - 8e-10 38.6 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCU99921.1 - 1.1e-05 25.3 0.0 2.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain RRM_1 PF00076.17 CCU99922.1 - 6.4e-12 44.9 0.0 3e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99922.1 - 6.3e-06 25.9 0.0 0.02 14.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99922.1 - 8.4e-06 25.6 0.1 0.0084 16.0 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NHase_beta PF02211.10 CCU99922.1 - 0.011 15.4 0.2 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Nitrile hydratase beta subunit Ras PF00071.17 CCU99923.1 - 6e-60 201.2 0.0 7.6e-60 200.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU99923.1 - 4.7e-18 65.8 0.1 6.2e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCU99923.1 - 4.5e-14 52.0 0.0 5.4e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCU99923.1 - 2.6e-07 30.0 0.0 3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCU99923.1 - 3.7e-07 29.7 0.0 4.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCU99923.1 - 7.4e-06 25.9 0.0 9.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCU99923.1 - 0.037 13.8 0.3 1.2 8.9 0.0 2.1 1 1 1 2 2 2 0 Dynamin family Hpr_kinase_C PF07475.7 CCU99923.1 - 0.041 13.1 0.1 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 CCU99923.1 - 0.079 13.1 0.1 0.51 10.4 0.0 2.2 1 1 1 2 2 2 0 AAA domain DUF1593 PF07632.6 CCU99923.1 - 0.091 12.0 0.2 0.17 11.1 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1593) Pantoate_ligase PF02569.10 CCU99924.1 - 4.8e-79 265.0 0.0 5.8e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Peptidase_M24 PF00557.19 CCU99925.1 - 8.9e-33 113.6 0.0 1.4e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 EF1G PF00647.14 CCU99927.1 - 2.2e-45 152.7 0.1 4.5e-45 151.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 CCU99927.1 - 9.4e-11 41.7 0.0 1.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CCU99927.1 - 1e-10 41.6 0.0 1.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCU99927.1 - 2.2e-10 40.8 0.1 4.8e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCU99927.1 - 2.7e-09 36.8 0.0 9.6e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCU99927.1 - 2e-07 30.8 0.1 4.1e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCU99927.1 - 3.5e-06 26.9 0.0 7.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.14 CCU99927.1 - 8.6 6.8 13.9 4 7.9 7.2 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Proteasome PF00227.21 CCU99928.1 - 2.1e-59 200.0 0.2 2.8e-59 199.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCU99928.1 - 3.5e-15 54.9 0.3 7e-15 54.0 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature LSM PF01423.17 CCU99929.1 - 4e-12 45.5 0.1 5.1e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCU99929.1 - 0.0023 17.8 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 CCU99929.1 - 0.09 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain HMG_box PF00505.14 CCU99930.1 - 4.4e-25 87.7 0.8 6.2e-25 87.2 0.6 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCU99930.1 - 2.9e-19 69.1 1.1 4.5e-19 68.5 0.8 1.3 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 CCU99930.1 - 0.0064 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.8 CCU99930.1 - 0.047 13.9 0.4 0.061 13.5 0.1 1.4 1 1 0 1 1 1 0 YABBY protein Phage_Cox PF10743.4 CCU99930.1 - 0.12 12.4 0.3 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Regulatory phage protein cox Mito_carr PF00153.22 CCU99931.1 - 1.9e-36 123.6 0.2 3.6e-25 87.4 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.22 CCU99932.1 - 1.2e-23 82.6 0.3 1.1e-19 69.9 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Reo_sigmaC PF04582.7 CCU99933.1 - 0.0058 15.8 4.4 0.012 14.8 0.2 2.2 2 0 0 2 2 2 1 Reovirus sigma C capsid protein DUF4201 PF13870.1 CCU99933.1 - 0.031 13.6 15.1 1.8 7.9 1.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) FlxA PF14282.1 CCU99933.1 - 0.062 13.2 4.0 0.63 10.0 1.3 2.9 1 1 1 2 2 2 0 FlxA-like protein RRM_1 PF00076.17 CCU99934.1 - 2.1e-73 241.9 0.0 2.7e-18 65.3 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99934.1 - 4e-65 215.7 0.1 5.6e-14 51.8 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99934.1 - 6.1e-31 106.0 0.0 1.1e-07 31.5 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCU99934.1 - 0.00061 19.4 0.1 0.1 12.3 0.0 3.8 4 1 1 5 5 5 1 Limkain b1 PCI PF01399.22 CCU99935.1 - 1.5e-22 79.9 0.6 4.5e-22 78.3 0.2 2.1 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 CCU99935.1 - 1e-19 70.6 2.2 4.8e-19 68.5 1.5 2.2 1 1 0 1 1 1 1 Proteasome regulatory subunit C-terminal Med10 PF09748.4 CCU99935.1 - 7.2e-12 45.2 0.0 4.9e-11 42.5 0.0 2.4 2 0 0 2 2 2 1 Transcription factor subunit Med10 of Mediator complex CTP_transf_2 PF01467.21 CCU99936.1 - 5.1e-16 59.1 0.0 1.2e-15 57.9 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase RRM_1 PF00076.17 CCU99937.1 - 1.7e-13 49.9 0.0 2.2e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99937.1 - 9.5e-10 38.1 0.0 1.3e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99937.1 - 6.3e-09 35.6 0.0 8.4e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCU99937.1 - 4.5e-05 23.1 0.0 6.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Complex1_LYR PF05347.10 CCU99938.1 - 2.9e-08 33.3 0.1 6.5e-08 32.2 0.1 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCU99938.1 - 3.4e-05 23.9 0.8 0.00016 21.8 0.6 1.9 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CCU99938.1 - 0.007 16.8 0.0 0.0093 16.4 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF3663 PF12404.3 CCU99938.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase Metallophos PF00149.23 CCU99939.1 - 1.6e-41 141.9 0.0 2.1e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pyr_redox_dim PF02852.17 CCU99940.1 - 3.4e-41 139.7 0.2 1e-40 138.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CCU99940.1 - 1.6e-29 103.2 15.2 6e-29 101.3 10.5 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCU99940.1 - 8.7e-24 83.7 6.8 3.7e-20 72.0 0.8 3.6 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCU99940.1 - 4.2e-12 45.8 7.8 4.3e-11 42.5 0.1 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCU99940.1 - 4.2e-09 35.9 4.5 0.0089 15.1 0.0 3.3 3 1 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 CCU99940.1 - 6.6e-09 35.6 4.9 0.0003 20.7 0.3 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCU99940.1 - 1.3e-08 35.1 2.1 0.00053 20.1 0.5 2.9 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCU99940.1 - 3e-07 29.2 11.5 8e-05 21.2 0.5 4.1 4 0 0 4 4 4 3 HI0933-like protein FAD_binding_2 PF00890.19 CCU99940.1 - 6.9e-07 28.4 2.3 6.9e-07 28.4 1.6 3.3 3 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 CCU99940.1 - 3.4e-06 26.3 5.2 0.00061 18.9 0.1 2.7 3 0 0 3 3 3 2 Thi4 family AlaDh_PNT_C PF01262.16 CCU99940.1 - 1.6e-05 24.5 2.9 0.011 15.3 0.2 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 CCU99940.1 - 6.7e-05 21.9 15.4 0.23 10.3 0.0 3.7 3 1 1 4 4 4 3 FAD dependent oxidoreductase GIDA PF01134.17 CCU99940.1 - 0.00027 19.9 14.3 0.0033 16.3 4.4 3.5 3 1 0 3 3 3 2 Glucose inhibited division protein A K_oxygenase PF13434.1 CCU99940.1 - 0.0015 17.5 0.6 0.28 10.0 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 CCU99940.1 - 0.0046 16.0 1.0 0.039 13.0 0.2 2.1 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 CCU99940.1 - 0.17 12.1 1.5 2.1 8.6 0.3 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 CCU99940.1 - 0.19 11.3 2.0 0.32 10.6 0.3 2.3 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 CCU99940.1 - 0.22 10.4 6.3 0.85 8.4 0.4 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein Mg_trans_NIPA PF05653.9 CCU99941.1 - 2.7e-62 210.4 3.3 3.7e-62 209.9 2.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 CCU99941.1 - 0.00064 19.8 2.1 0.00064 19.8 1.5 3.8 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CCU99941.1 - 0.0045 17.0 3.5 0.0045 17.0 2.4 3.4 3 1 1 4 4 4 1 EamA-like transporter family DEC-1_N PF04625.8 CCU99941.1 - 0.78 8.3 5.4 1.1 7.7 3.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MT-A70 PF05063.9 CCU99942.1 - 3.6e-39 134.1 0.0 4.8e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Bap31 PF05529.7 CCU99943.1 - 4.5e-47 159.9 8.0 5.6e-47 159.7 5.6 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Ndc1_Nup PF09531.5 CCU99943.1 - 0.00023 19.7 2.0 0.00025 19.6 1.4 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF1077 PF06417.7 CCU99943.1 - 0.006 15.9 0.8 0.011 15.0 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1077) SecY PF00344.15 CCU99943.1 - 0.11 11.4 2.8 0.12 11.3 1.9 1.2 1 0 0 1 1 1 0 SecY translocase GrpE PF01025.14 CCU99943.1 - 0.64 9.5 4.7 4.4 6.8 2.2 2.0 2 0 0 2 2 2 0 GrpE DivIC PF04977.10 CCU99943.1 - 0.81 9.2 4.3 1.4 8.4 1.5 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF2140 PF09911.4 CCU99943.1 - 1.1 8.4 4.4 0.9 8.6 0.1 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF89 PF01937.14 CCU99944.1 - 8.1e-107 357.0 0.0 9.3e-107 356.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 NIF3 PF01784.13 CCU99945.1 - 5.9e-52 176.6 0.0 8e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RNA_pol_Rpb2_6 PF00562.23 CCU99946.1 - 5.9e-122 407.1 0.0 1.1e-121 406.2 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCU99946.1 - 4.1e-57 192.3 0.1 1.3e-56 190.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCU99946.1 - 3.4e-36 124.4 0.3 7.4e-36 123.3 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCU99946.1 - 1.8e-28 98.6 0.1 4.7e-28 97.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CCU99946.1 - 9.5e-23 79.7 0.2 6.2e-22 77.1 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CCU99946.1 - 9.7e-21 73.3 0.0 2.1e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CCU99946.1 - 2.8e-12 46.3 0.1 9.1e-12 44.7 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 DUF3128 PF11326.3 CCU99947.1 - 1.1e-21 76.7 0.3 1.5e-21 76.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Prefoldin PF02996.12 CCU99948.1 - 7.6e-26 90.1 0.0 1.3e-25 89.4 0.0 1.4 1 1 0 1 1 1 1 Prefoldin subunit GTP_EFTU PF00009.22 CCU99949.1 - 2.7e-34 118.2 2.6 2.7e-34 118.2 1.8 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CCU99949.1 - 3.1e-22 78.5 0.1 1.1e-21 76.7 0.0 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CCU99949.1 - 8.9e-14 51.3 1.1 2.5e-05 24.3 0.8 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCU99949.1 - 1.2e-06 28.4 0.1 4.6e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCU99949.1 - 5.4e-05 22.5 0.1 0.00013 21.2 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 CCU99949.1 - 0.00079 18.9 0.5 0.011 15.1 0.4 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CCU99949.1 - 0.0021 17.3 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CCU99949.1 - 0.0022 18.5 0.0 0.0042 17.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 CCU99949.1 - 0.058 13.1 0.2 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU_D4 PF14578.1 CCU99949.1 - 0.063 12.9 0.7 0.27 10.9 0.2 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.18 CCU99949.1 - 0.46 10.2 3.0 19 5.0 0.0 3.1 2 1 0 3 3 3 0 Dynamin family UQ_con PF00179.21 CCU99950.1 - 1.7e-45 153.8 0.0 2e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCU99950.1 - 0.038 13.7 0.1 0.15 11.8 0.1 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B CAF1 PF04857.15 CCU99951.1 - 3.5e-60 203.5 0.0 4.6e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease VWA_2 PF13519.1 CCU99952.1 - 1.2e-08 35.2 0.2 3e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 CCU99952.1 - 9.6e-08 30.9 17.9 0.024 14.1 1.6 4.0 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.9 CCU99952.1 - 0.019 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Ssl1-like RNase_PH PF01138.16 CCU99955.1 - 5.7e-26 91.3 0.0 1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCU99955.1 - 0.00021 21.1 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Fimbrial_CS1 PF04449.7 CCU99955.1 - 0.1 12.6 0.0 3.1 7.8 0.0 2.2 2 0 0 2 2 2 0 CS1 type fimbrial major subunit Gp_dh_C PF02800.15 CCU99956.1 - 3e-72 241.2 0.0 4.2e-72 240.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CCU99956.1 - 5.7e-59 198.4 0.1 1.1e-58 197.5 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain RhoGEF PF00621.15 CCU99957.1 - 8.2e-39 133.3 1.3 8.2e-39 133.3 0.9 1.6 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.1 CCU99957.1 - 5.2e-28 97.5 0.0 7.7e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain CDC24 PF06395.6 CCU99957.1 - 1.6e-24 85.7 0.0 2.7e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 CCU99957.1 - 0.00067 19.2 0.3 0.0025 17.4 0.1 2.0 2 0 0 2 2 2 1 PB1 domain PH PF00169.24 CCU99957.1 - 0.044 13.9 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 PH domain Abhydrolase_3 PF07859.8 CCU99957.1 - 0.068 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioredoxin PF00085.15 CCU99958.1 - 2.4e-56 187.8 0.6 9.7e-30 102.3 0.0 4.5 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CCU99958.1 - 2.1e-35 122.2 0.0 4.3e-25 88.5 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CCU99958.1 - 1.4e-11 44.5 0.4 0.003 17.7 0.3 4.5 3 2 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCU99958.1 - 7.5e-11 42.0 0.0 0.019 15.0 0.0 4.5 4 1 0 4 4 4 3 Thioredoxin-like Thioredoxin_7 PF13899.1 CCU99958.1 - 1e-09 38.2 0.2 0.00068 19.6 0.0 3.8 4 0 0 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 CCU99958.1 - 2.2e-08 33.7 0.8 0.2 11.3 0.0 4.4 4 1 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 CCU99958.1 - 6.7e-05 22.4 1.4 0.51 9.8 0.0 3.4 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.1 CCU99958.1 - 0.0028 17.6 0.2 2.3 8.2 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_9 PF14595.1 CCU99958.1 - 0.0065 16.0 0.1 2 7.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ALO PF04030.9 CCU99959.1 - 7.8e-63 212.4 0.2 1.2e-62 211.8 0.1 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 CCU99959.1 - 2.3e-20 72.4 0.0 4.5e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain PCI PF01399.22 CCU99960.1 - 6e-11 42.5 0.0 2.5e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain PIG-L PF02585.12 CCU99961.1 - 1.8e-23 83.4 0.8 2.7e-23 82.8 0.6 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Pkinase PF00069.20 CCU99962.1 - 6.3e-49 166.4 0.0 4.6e-48 163.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99962.1 - 1.6e-26 92.9 0.0 2.1e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCU99962.1 - 3.8e-05 22.7 0.0 7.1e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCU99962.1 - 0.0012 18.6 3.1 0.048 13.3 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Gemini_AL2 PF01440.11 CCU99962.1 - 0.005 16.9 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Geminivirus AL2 protein Choline_kinase PF01633.15 CCU99962.1 - 0.068 12.7 0.0 0.69 9.4 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 CCU99962.1 - 0.077 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VHS PF00790.14 CCU99963.1 - 0.00022 20.9 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 VHS domain HIG_1_N PF04588.8 CCU99964.1 - 4e-09 36.0 3.4 5.9e-09 35.5 2.3 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PmbA_TldD PF01523.11 CCU99964.1 - 0.96 8.6 4.0 0.69 9.1 1.6 1.5 1 1 1 2 2 2 0 Putative modulator of DNA gyrase muHD PF10291.4 CCU99965.1 - 2.2e-26 92.5 0.0 3.5e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 CCU99965.1 - 9.9e-08 32.0 1.2 1.5e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Adap_comp_sub PF00928.16 CCU99965.1 - 0.051 12.6 0.0 0.21 10.6 0.0 1.8 1 1 0 1 1 1 0 Adaptor complexes medium subunit family Pkinase PF00069.20 CCU99966.1 - 2.6e-71 239.8 0.0 3.1e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCU99966.1 - 5e-32 110.9 0.0 6.2e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCU99966.1 - 0.00014 21.0 0.0 0.00038 19.5 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCU99966.1 - 0.00079 19.2 0.1 0.0021 17.8 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCU99966.1 - 0.0061 15.5 0.0 0.0094 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CCU99966.1 - 0.059 12.7 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Mid1 PF12929.2 CCU99967.1 - 2.7e-71 240.5 0.0 5.3e-71 239.5 0.0 1.4 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 CCU99967.1 - 0.014 15.7 2.4 0.26 11.6 0.1 2.4 2 0 0 2 2 2 0 Fz domain FtsJ PF01728.14 CCU99967.1 - 0.014 15.4 0.1 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Rft-1 PF04506.8 CCU99968.1 - 2.4e-51 174.7 0.0 2.4e-37 128.5 0.0 2.3 2 0 0 2 2 2 2 Rft protein Membr_traf_MHD PF10540.4 CCU99969.1 - 2e-16 60.0 0.0 8.5e-16 57.9 0.0 2.2 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 CCU99969.1 - 0.036 13.9 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 C2 domain RRM_1 PF00076.17 CCU99970.1 - 3.7e-39 132.1 0.0 4.9e-19 67.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCU99970.1 - 4.2e-34 116.3 0.1 5.8e-16 58.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCU99970.1 - 5.8e-15 54.8 0.0 3.7e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCU99970.1 - 0.12 12.2 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif PTR2 PF00854.16 CCU99971.1 - 7.8e-33 113.7 11.1 1.7e-31 109.3 5.0 2.9 1 1 1 2 2 2 2 POT family RNA_pol_L_2 PF13656.1 CCU99972.1 - 1.2e-26 91.9 0.0 1.5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CCU99972.1 - 2.8e-13 48.7 0.0 4.1e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sec1 PF00995.18 CCU99974.1 - 1.7e-133 446.2 0.0 2e-133 446.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family IFT20 PF14931.1 CCU99974.1 - 0.043 13.7 0.1 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Aa_trans PF01490.13 CCU99975.1 - 6.7e-16 57.7 44.2 1.3e-15 56.7 30.6 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Mito_carr PF00153.22 CCU99976.1 - 5.3e-47 157.4 0.2 1.1e-20 73.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Utp21 PF04192.7 CCU99980.1 - 7.9e-48 162.6 0.0 1.3e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 CCU99980.1 - 3.7e-16 58.3 6.6 0.0053 16.5 0.0 8.3 8 0 0 8 8 8 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCU99980.1 - 0.019 14.4 0.0 0.22 11.0 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.11 CCU99980.1 - 0.027 12.8 2.9 0.2 9.9 0.0 3.1 4 0 0 4 4 4 0 Cytochrome D1 heme domain Hira PF07569.6 CCU99980.1 - 0.17 11.0 0.1 23 4.1 0.0 3.9 5 1 1 6 6 6 0 TUP1-like enhancer of split DEAD PF00270.24 CCU99981.1 - 3.5e-43 147.0 0.1 6.1e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCU99981.1 - 1.8e-21 75.7 0.0 5.3e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CCU99981.1 - 1.5e-20 72.5 0.4 3e-20 71.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CCU99981.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit WD40 PF00400.27 CCU99982.1 - 5e-47 156.1 17.1 6.7e-10 38.4 0.0 11.6 13 0 0 13 13 13 6 WD domain, G-beta repeat Utp12 PF04003.7 CCU99982.1 - 4.1e-16 58.8 0.1 7e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 CCU99982.1 - 0.0015 18.2 1.1 1.2 8.8 0.1 4.8 4 1 2 6 6 6 1 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 CCU99982.1 - 0.11 11.3 0.1 1.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) PQQ_3 PF13570.1 CCU99982.1 - 0.87 9.9 4.9 13 6.1 0.0 5.1 5 1 1 6 6 6 0 PQQ-like domain Cyclin_N PF00134.18 CCU99983.1 - 3.3e-13 49.2 0.1 5.2e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCU99983.1 - 3.6e-10 40.4 0.8 5.6e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Cyclin Perilipin PF03036.11 CCU99984.1 - 3.7e-06 26.0 9.0 0.00031 19.7 0.3 2.2 2 0 0 2 2 2 2 Perilipin family DUF148 PF02520.12 CCU99984.1 - 0.0035 17.1 8.4 0.1 12.3 0.2 2.8 1 1 1 2 2 2 1 Domain of unknown function DUF148 DUF911 PF06023.7 CCU99984.1 - 0.0063 15.7 0.8 0.01 15.0 0.5 1.2 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) IncA PF04156.9 CCU99984.1 - 0.0073 15.9 3.3 0.01 15.4 2.3 1.2 1 0 0 1 1 1 1 IncA protein Gp58 PF07902.6 CCU99984.1 - 0.0081 14.4 1.4 0.0079 14.4 1.0 1.1 1 0 0 1 1 1 1 gp58-like protein SF-assemblin PF06705.6 CCU99984.1 - 0.014 14.5 3.3 0.44 9.6 1.9 2.0 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF3038 PF11237.3 CCU99984.1 - 0.015 15.1 0.7 0.034 13.9 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) DUF883 PF05957.8 CCU99984.1 - 0.052 13.9 2.5 0.58 10.5 0.7 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) UPF0147 PF03685.8 CCU99984.1 - 0.083 12.7 0.1 0.41 10.5 0.0 2.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0147) ApoLp-III PF07464.6 CCU99984.1 - 0.11 12.4 9.1 0.2 11.6 6.1 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) LUC7 PF03194.10 CCU99984.1 - 0.13 11.7 3.1 0.18 11.3 2.1 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Muted PF14942.1 CCU99984.1 - 0.13 12.0 4.4 0.28 11.0 3.0 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein CtIP_N PF10482.4 CCU99984.1 - 0.15 11.8 1.8 0.33 10.7 0.9 1.9 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Erp_C PF06780.6 CCU99984.1 - 0.21 11.4 2.6 0.35 10.6 0.9 1.9 1 1 1 2 2 2 0 Erp protein C-terminus MbeD_MobD PF04899.7 CCU99984.1 - 0.3 11.0 5.8 0.96 9.3 4.0 1.9 1 1 0 1 1 1 0 MbeD/MobD like DUF948 PF06103.6 CCU99984.1 - 0.61 9.9 3.5 13 5.7 0.8 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.9 CCU99984.1 - 0.78 9.6 12.7 1.4 8.7 8.8 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FBPase PF00316.15 CCU99985.1 - 1.1e-128 428.6 0.0 1.3e-128 428.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 CCU99985.1 - 0.016 14.5 0.0 0.036 13.3 0.0 1.5 2 0 0 2 2 2 0 Inositol monophosphatase family Amino_oxidase PF01593.19 CCU99986.1 - 9.9e-12 44.6 0.0 2.6e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CCU99986.1 - 3.4e-11 42.9 0.0 6.4e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCU99986.1 - 1.7e-06 27.1 0.1 2.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 CCU99986.1 - 0.00086 18.4 0.0 0.019 14.0 0.0 2.6 3 0 0 3 3 3 1 Thi4 family Pyr_redox_3 PF13738.1 CCU99986.1 - 0.0031 17.6 0.1 0.12 12.4 0.0 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCU99986.1 - 0.0047 16.7 0.0 0.0096 15.7 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 CCU99986.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 CCU99986.1 - 0.012 14.2 0.1 0.18 10.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 CCU99986.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UCR_14kD PF02271.11 CCU99987.1 - 5.1e-38 129.0 0.9 5.9e-38 128.8 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Solute_trans_a PF03619.11 CCU99988.1 - 9.2e-11 41.5 0.0 1e-10 41.4 0.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha RINT1_TIP1 PF04437.8 CCU99990.1 - 1.1e-62 212.2 0.0 2.6e-62 211.0 0.0 1.6 1 1 0 1 1 1 1 RINT-1 / TIP-1 family Translin PF01997.11 CCU99990.1 - 3.7e-27 95.2 0.9 3.9e-26 91.8 0.6 2.7 1 1 0 1 1 1 1 Translin family Spore_coat_CotO PF14153.1 CCU99991.1 - 0.074 12.4 1.0 0.073 12.5 0.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Na_trans_assoc PF06512.8 CCU99991.1 - 0.21 11.5 5.8 0.3 11.0 4.1 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated BSP_II PF05432.6 CCU99991.1 - 1.2 8.3 9.9 1.8 7.8 6.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DNA_pol_phi PF04931.8 CCU99991.1 - 6.2 4.4 11.2 8 4.0 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi MIP-T3 PF10243.4 CCU99992.1 - 2.6e-05 22.9 24.4 2.6e-05 22.9 16.9 2.7 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 Borrelia_P83 PF05262.6 CCU99992.1 - 0.23 9.6 28.9 0.0042 15.4 12.5 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein CAF-1_p150 PF11600.3 CCU99992.1 - 8.3 5.7 65.2 0.67 9.2 37.2 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MCM PF00493.18 CCU99993.1 - 5.2e-127 423.2 0.0 6.9e-127 422.8 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCU99993.1 - 1.6e-20 73.8 0.0 3.2e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCU99993.1 - 4.7e-08 32.4 0.0 9e-07 28.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCU99993.1 - 0.0024 17.4 0.0 0.0065 16.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCU99993.1 - 0.0049 16.3 0.0 0.016 14.7 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 CCU99993.1 - 0.033 13.9 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ras PF00071.17 CCU99994.1 - 3.6e-62 208.5 0.2 4.4e-62 208.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCU99994.1 - 5e-21 75.4 0.0 7.1e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCU99994.1 - 7.8e-13 48.0 0.0 1.1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCU99994.1 - 1.4e-06 28.1 0.1 1.9e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCU99994.1 - 3.7e-05 23.2 0.1 0.0002 20.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CCU99994.1 - 7e-05 22.9 0.0 0.0002 21.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 CCU99994.1 - 0.00028 20.0 0.1 0.00053 19.1 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 CCU99994.1 - 0.0024 16.9 0.0 0.0037 16.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 CCU99994.1 - 0.0081 15.3 0.0 0.014 14.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CCU99994.1 - 0.012 15.5 0.3 0.034 14.1 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 CCU99994.1 - 0.02 14.3 0.0 0.041 13.3 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CCU99994.1 - 0.027 14.7 0.2 0.039 14.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.11 CCU99994.1 - 0.03 13.5 0.0 0.081 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 CCU99994.1 - 0.05 13.1 0.1 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CCU99994.1 - 0.074 12.9 0.0 0.21 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CCU99994.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 CCU99994.1 - 0.085 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CCU99994.1 - 0.1 11.8 0.1 0.49 9.6 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.1 CCU99994.1 - 0.12 12.3 0.1 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Trehalase PF01204.13 CCU99994.1 - 0.13 10.9 0.1 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 Trehalase UQ_con PF00179.21 CCU99995.1 - 1.4e-39 134.7 0.0 1.5e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCU99995.1 - 0.00016 21.3 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCU99995.1 - 0.067 13.0 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.6 CCU99995.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Xpo1 PF08389.7 CCU99996.1 - 7.2e-23 81.1 0.0 2.3e-22 79.4 0.0 2.0 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.14 CCU99996.1 - 3.6e-07 29.9 0.4 9.7e-07 28.6 0.1 1.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain AAA PF00004.24 CCU99997.1 - 1.7e-41 141.5 0.0 2.9e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CCU99997.1 - 1.4e-09 37.7 0.1 3.7e-08 33.1 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 CCU99997.1 - 1.9e-06 28.0 0.6 0.0019 18.3 0.0 2.7 2 1 1 3 3 2 1 AAA domain MIT PF04212.13 CCU99997.1 - 5e-06 26.2 0.9 5e-06 26.2 0.6 2.0 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_5 PF07728.9 CCU99997.1 - 5.7e-06 26.1 0.0 2.9e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CCU99997.1 - 3e-05 24.8 0.0 0.0001 23.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CCU99997.1 - 6.1e-05 22.5 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CCU99997.1 - 6.2e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCU99997.1 - 8.6e-05 22.0 0.2 0.048 13.0 0.1 2.3 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCU99997.1 - 0.00015 21.7 0.1 0.0034 17.3 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CCU99997.1 - 0.00016 20.8 0.0 0.00028 19.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CCU99997.1 - 0.00019 21.3 0.0 0.00045 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CCU99997.1 - 0.00077 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CCU99997.1 - 0.0012 17.7 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 CCU99997.1 - 0.0014 17.4 0.0 0.0023 16.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 CCU99997.1 - 0.0026 17.2 0.0 0.073 12.5 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 CCU99997.1 - 0.0028 17.7 0.0 0.014 15.5 0.0 2.1 2 0 0 2 2 2 1 RNA helicase KaiC PF06745.8 CCU99997.1 - 0.0052 15.9 0.3 1.6 7.7 0.0 2.7 2 1 1 3 3 3 1 KaiC Mg_chelatase PF01078.16 CCU99997.1 - 0.018 14.2 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CCU99997.1 - 0.029 14.1 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 CCU99997.1 - 0.03 14.3 0.0 0.088 12.8 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 CCU99997.1 - 0.036 14.0 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CCU99997.1 - 0.036 13.6 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CCU99997.1 - 0.04 14.2 1.1 0.073 13.3 0.0 2.1 3 0 0 3 3 1 0 AAA domain Zeta_toxin PF06414.7 CCU99997.1 - 0.046 12.8 0.1 1.4 7.9 0.0 2.4 1 1 1 2 2 2 0 Zeta toxin CPT PF07931.7 CCU99997.1 - 0.06 12.9 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein Arch_ATPase PF01637.13 CCU99997.1 - 0.071 12.8 0.2 1 9.0 0.0 2.3 2 1 1 3 3 3 0 Archaeal ATPase PhoH PF02562.11 CCU99997.1 - 0.088 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.6 CCU99997.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_10 PF12846.2 CCU99997.1 - 0.14 11.6 0.4 0.5 9.7 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 CCU99997.1 - 0.19 11.6 0.2 2.6 7.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain PLDc PF00614.17 CCU99998.1 - 1.5e-11 43.6 0.7 3.8e-05 23.3 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CCU99998.1 - 1.5e-11 44.0 0.1 2.3e-07 30.6 0.0 3.1 3 1 0 3 3 3 2 PLD-like domain PX PF00787.19 CCU99998.1 - 0.0002 21.1 1.6 0.00036 20.3 0.1 2.1 2 0 0 2 2 2 1 PX domain PH PF00169.24 CCU99998.1 - 0.0051 16.9 0.3 0.011 15.9 0.2 1.6 1 0 0 1 1 1 1 PH domain Citrate_synt PF00285.16 CCU99999.1 - 4.6e-101 338.0 0.0 5.7e-101 337.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase DUF443 PF04276.7 CCV00000.1 - 0.012 15.0 0.1 0.013 14.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF443) DUF4234 PF14018.1 CCV00000.1 - 0.019 14.6 0.7 0.021 14.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Use1 PF09753.4 CCV00000.1 - 0.021 14.2 0.7 0.022 14.2 0.5 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 SNARE PF05739.14 CCV00000.1 - 0.029 14.0 0.6 0.033 13.8 0.4 1.1 1 0 0 1 1 1 0 SNARE domain Sec20 PF03908.8 CCV00000.1 - 0.08 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Sec20 DUF1129 PF06570.6 CCV00000.1 - 0.11 11.8 0.8 0.11 11.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Rhomboid PF01694.17 CCV00001.1 - 7.3e-06 26.0 18.6 0.0006 19.8 9.5 2.8 2 1 0 2 2 2 1 Rhomboid family KilA-N PF04383.8 CCV00002.1 - 0.0024 17.4 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 KilA-N domain Abhydrolase_3 PF07859.8 CCV00003.1 - 6.2e-20 71.6 0.0 1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCV00003.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glucan_synthase PF02364.10 CCV00004.1 - 0 1327.0 0.0 0 1326.5 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CCV00004.1 - 6.6e-37 125.9 0.0 1.5e-36 124.8 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 p450 PF00067.17 CCV00005.1 - 6.9e-51 173.2 0.0 8.9e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tfb4 PF03850.9 CCV00006.1 - 1.1e-10 41.2 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Pertactin PF03212.9 CCV00006.1 - 0.12 12.0 0.1 0.27 10.9 0.0 1.5 1 1 1 2 2 2 0 Pertactin Cyclin_N PF00134.18 CCV00007.1 - 5.8e-09 35.5 0.0 6.6e-08 32.1 0.0 2.3 1 1 0 1 1 1 1 Cyclin, N-terminal domain Histone PF00125.19 CCV00008.1 - 1.4e-22 79.5 0.4 1.9e-22 79.1 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCV00008.1 - 1.2e-06 28.4 0.1 3e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CCV00008.1 - 0.00033 20.8 0.0 0.00052 20.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 CCV00008.1 - 0.01 16.3 0.1 0.014 15.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Mitofilin PF09731.4 CCV00008.1 - 0.023 13.3 0.9 0.027 13.1 0.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3530 PF12048.3 CCV00008.1 - 0.05 12.5 1.0 0.06 12.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) RP-C PF03428.8 CCV00008.1 - 0.057 12.8 0.1 0.1 12.0 0.1 1.4 1 1 0 1 1 1 0 Replication protein C N-terminal domain Bt_P21 PF05560.6 CCV00008.1 - 0.072 12.4 0.0 0.086 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein DUF4629 PF15442.1 CCV00008.1 - 4.9 7.2 10.0 0.86 9.7 4.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) Histone PF00125.19 CCV00009.1 - 7.2e-26 90.1 0.0 9.2e-26 89.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCV00009.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Iso_dh PF00180.15 CCV00010.1 - 2.6e-80 270.0 0.0 3.2e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.15 CCV00011.1 - 2e-99 332.8 0.0 2.3e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RRM_1 PF00076.17 CCV00012.1 - 2.3e-18 65.5 0.0 3.5e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCV00012.1 - 9.7e-15 54.3 0.0 1.6e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCV00012.1 - 2.6e-12 46.4 0.0 3.9e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L18e PF00828.14 CCV00013.1 - 7.2e-25 87.8 0.9 1e-24 87.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 LisH PF08513.6 CCV00014.1 - 0.00064 19.3 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 LisH DUF1424 PF07232.6 CCV00014.1 - 0.0086 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Putative rep protein (DUF1424) Adap_comp_sub PF00928.16 CCV00015.1 - 1.5e-88 296.3 0.0 2e-88 295.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CCV00015.1 - 4.1e-07 29.8 0.1 7.3e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SH3_5 PF08460.5 CCV00015.1 - 0.055 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain RhoGEF PF00621.15 CCV00016.1 - 8e-26 91.0 0.0 1.2e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 CCV00016.1 - 0.00022 21.3 0.0 0.00053 20.1 0.0 1.6 1 0 0 1 1 1 1 PH domain Nol1_Nop2_Fmu PF01189.12 CCV00017.1 - 1.4e-17 64.0 0.0 5e-16 58.9 0.0 2.2 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CCV00017.1 - 0.0041 17.1 0.2 0.012 15.6 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CCV00017.1 - 0.0089 16.0 0.0 0.014 15.3 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Phlebovirus_G2 PF07245.6 CCV00017.1 - 0.02 13.1 0.0 0.027 12.7 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 MTS PF05175.9 CCV00017.1 - 0.11 11.8 0.0 0.95 8.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain ApbA_C PF08546.6 CCV00018.1 - 1e-18 67.4 0.0 1.7e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CCV00018.1 - 9.2e-09 34.9 0.2 3.5e-08 33.0 0.2 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HbrB PF08539.6 CCV00019.1 - 1.7e-24 86.4 0.0 3e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 HbrB-like PMSR PF01625.16 CCV00020.1 - 1e-54 184.6 0.3 1.2e-54 184.4 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase UQ_con PF00179.21 CCV00021.1 - 1.2e-23 83.1 0.0 1.3e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DIOX_N PF14226.1 CCV00022.1 - 1.2e-11 45.2 0.0 2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCV00022.1 - 1.6e-09 37.9 0.0 1e-08 35.3 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF2517 PF10725.4 CCV00022.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) Lipoprotein_Ltp PF07553.6 CCV00022.1 - 0.16 11.8 0.1 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein Rapamycin_bind PF08771.6 CCV00023.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Rapamycin binding domain TRAM_LAG1_CLN8 PF03798.11 CCV00024.1 - 2.9e-05 23.7 16.9 2.9e-05 23.7 11.7 2.0 1 1 1 2 2 2 1 TLC domain Peptidase_S10 PF00450.17 CCV00025.1 - 5.2e-100 335.5 0.0 7e-100 335.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase IBN_N PF03810.14 CCV00025.1 - 1.3e-09 37.8 0.2 2.1e-08 33.9 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 CCV00025.1 - 0.0019 18.4 15.3 0.038 14.2 0.3 4.8 4 0 0 4 4 4 2 HEAT repeats Xpo1 PF08389.7 CCV00025.1 - 0.069 13.0 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Exportin 1-like protein SNF2_N PF00176.18 CCV00026.1 - 4.7e-65 219.3 0.0 6.8e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCV00026.1 - 3.3e-07 30.0 0.0 3.1e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 CCV00026.1 - 1.2e-06 28.0 8.7 2.6e-06 27.0 6.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCV00026.1 - 9.1e-06 25.4 10.3 2.1e-05 24.2 7.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCV00026.1 - 0.0018 17.9 7.7 0.0037 16.8 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCV00026.1 - 0.0029 17.6 9.1 0.0064 16.4 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 CCV00026.1 - 0.1 12.4 0.1 1 9.1 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.1 CCV00026.1 - 0.16 11.6 3.3 0.43 10.3 2.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 CCV00026.1 - 0.26 10.8 7.9 1.4 8.5 5.5 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CCV00026.1 - 0.44 10.3 3.8 1.3 8.8 2.7 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CCV00026.1 - 2.3 8.1 7.6 7.6 6.5 5.3 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING 2OG-FeII_Oxy_2 PF13532.1 CCV00027.1 - 9.5e-09 35.3 0.0 3.7e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CCV00027.1 - 4.4e-06 26.8 0.0 0.00027 21.1 0.0 2.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 CCV00028.1 - 1.9e-40 138.6 0.0 4.6e-27 94.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCV00028.1 - 3.1e-21 75.6 0.0 2.6e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CCV00028.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CCV00028.1 - 0.086 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCV00028.1 - 0.3 9.9 0.0 9.8 5.0 0.0 2.6 3 0 0 3 3 3 0 Kinase-like Mif2_N PF15624.1 CCV00028.1 - 4.9 7.7 9.0 1.3 9.6 2.4 2.8 2 1 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal AATase PF07247.7 CCV00029.1 - 0.099 11.1 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase Ribosomal_S6e PF01092.14 CCV00030.1 - 2.6e-53 179.0 0.2 4.7e-53 178.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.7 CCV00031.1 - 2.8e-29 100.7 0.5 4.7e-29 100.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CCV00031.1 - 1.3e-21 76.1 0.0 1.9e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 CCV00031.1 - 0.00052 19.7 0.2 0.0011 18.7 0.0 1.6 2 1 0 2 2 2 1 'Paired box' domain zf-H2C2_2 PF13465.1 CCV00032.1 - 5.8e-24 83.1 47.3 5.1e-07 29.6 0.9 7.2 8 0 0 8 8 8 4 Zinc-finger double domain IPK PF03770.11 CCV00032.1 - 7.4e-23 81.2 0.0 1.3e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase zf-C2H2 PF00096.21 CCV00032.1 - 2.6e-17 62.0 51.6 1.6e-05 24.9 0.3 8.3 8 0 0 8 8 8 6 Zinc finger, C2H2 type Lipase_3 PF01764.20 CCV00032.1 - 3.5e-17 62.3 0.0 6.6e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) zf-C2H2_4 PF13894.1 CCV00032.1 - 8.6e-08 31.9 57.5 0.0011 19.0 0.2 8.5 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCV00032.1 - 0.0003 20.8 7.7 0.007 16.4 0.1 4.1 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding DUF676 PF05057.9 CCV00032.1 - 0.03 13.6 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) MAP65_ASE1 PF03999.7 CCV00033.1 - 7.8e-52 176.7 1.8 9.4e-48 163.2 0.0 3.1 3 0 0 3 3 3 2 Microtubule associated protein (MAP65/ASE1 family) Vps52 PF04129.7 CCV00033.1 - 1.9e-24 86.0 0.0 7e-22 77.6 0.0 3.2 2 1 0 2 2 2 1 Vps52 / Sac2 family CENP-F_leu_zip PF10473.4 CCV00033.1 - 0.0027 17.5 1.2 0.0027 17.5 0.8 2.6 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 CCV00033.1 - 0.0051 16.6 1.2 3.9 7.3 0.0 3.3 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 CCV00033.1 - 0.012 15.5 2.9 2.7 7.8 0.1 3.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 CCV00033.1 - 0.042 12.5 2.9 0.38 9.3 0.2 2.9 3 0 0 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.7 CCV00033.1 - 0.044 14.0 0.3 8.5 6.7 0.0 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PspB PF06667.7 CCV00033.1 - 0.091 12.7 1.0 0.42 10.5 0.7 2.2 1 0 0 1 1 1 0 Phage shock protein B Sec8_exocyst PF04048.9 CCV00033.1 - 0.11 12.1 1.9 0.92 9.1 0.1 2.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain GAS PF13851.1 CCV00033.1 - 0.37 9.9 6.3 0.18 10.9 0.3 3.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 CCV00033.1 - 0.51 8.7 0.7 2 6.7 0.3 1.9 2 0 0 2 2 2 0 AAA domain DUF904 PF06005.7 CCV00033.1 - 0.9 9.8 6.2 3.1 8.1 1.2 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF904) ATG16 PF08614.6 CCV00033.1 - 1.6 8.5 10.1 0.081 12.7 1.4 2.9 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 CCV00033.1 - 1.6 8.2 7.8 3.9 7.0 1.1 3.6 3 0 0 3 3 3 0 Septum formation initiator Filament PF00038.16 CCV00033.1 - 5.6 6.3 16.3 0.39 10.1 1.3 3.6 4 0 0 4 4 4 0 Intermediate filament protein ADIP PF11559.3 CCV00033.1 - 9.5 6.1 19.3 0.066 13.1 1.5 3.3 5 0 0 5 5 3 0 Afadin- and alpha -actinin-Binding LRR_4 PF12799.2 CCV00034.1 - 2.1e-33 113.3 0.0 5e-06 26.0 0.0 7.8 6 1 4 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCV00034.1 - 5.3e-29 99.7 13.8 1.5e-11 43.9 0.5 6.7 6 2 0 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 CCV00034.1 - 4e-13 47.4 17.0 0.16 12.1 0.1 11.9 14 0 0 14 14 14 4 Leucine Rich Repeat LRR_7 PF13504.1 CCV00034.1 - 2.5e-11 41.8 26.9 0.27 11.5 0.1 12.7 14 0 0 14 14 14 3 Leucine rich repeat LRR_6 PF13516.1 CCV00034.1 - 1e-07 31.2 5.6 4.3 7.7 0.1 8.5 7 3 3 10 10 10 2 Leucine Rich repeat LRR_9 PF14580.1 CCV00034.1 - 1.8e-05 24.3 2.8 0.0027 17.3 0.0 3.6 2 1 2 4 4 4 2 Leucine-rich repeat Lum_binding PF00677.12 CCV00035.1 - 3.6e-28 97.2 0.0 3e-17 62.2 0.0 3.5 2 1 0 2 2 2 2 Lumazine binding domain G10 PF01125.12 CCV00036.1 - 9e-58 193.9 6.5 1.9e-57 192.9 4.5 1.5 1 1 0 1 1 1 1 G10 protein DEP PF00610.16 CCV00037.1 - 0.00075 19.1 0.0 0.042 13.6 0.0 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RGS PF00615.14 CCV00037.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Regulator of G protein signaling domain Hist_deacetyl PF00850.14 CCV00038.1 - 2.7e-88 296.2 0.0 4.1e-88 295.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 CCV00038.1 - 4.8e-08 32.6 0.0 7.6e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Med20 PF08612.6 CCV00040.1 - 0.00044 19.4 0.0 0.001 18.2 0.0 1.4 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex SIP PF04954.8 CCV00041.1 - 1 9.7 5.4 1.9 8.8 0.9 3.0 3 1 0 3 3 3 0 Siderophore-interacting protein JAB PF01398.16 CCV00042.1 - 8.5e-36 122.1 0.0 1.4e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CCV00042.1 - 2.8e-27 95.1 0.9 4.2e-27 94.5 0.1 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 CCV00042.1 - 2.8e-09 36.4 0.0 4.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CCV00042.1 - 0.042 13.3 0.1 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Exotox-A_target PF09102.5 CCV00042.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A, targeting NicO PF03824.11 CCV00044.1 - 2.8e-41 141.6 0.7 9.3e-24 84.2 0.1 4.0 4 1 0 4 4 4 2 High-affinity nickel-transport protein Selenoprotein_S PF06936.6 CCV00044.1 - 0.016 14.7 0.5 0.064 12.7 0.2 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) DUF1404 PF07185.6 CCV00044.1 - 0.024 14.1 1.2 0.024 14.1 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1404) DUF1191 PF06697.7 CCV00044.1 - 0.031 13.1 0.8 0.09 11.5 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1191) Myb_CC_LHEQLE PF14379.1 CCV00044.1 - 0.18 11.4 0.9 0.36 10.4 0.1 2.0 2 1 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif Cuticle_3 PF11018.3 CCV00044.1 - 0.18 11.9 5.7 0.26 11.3 3.9 1.2 1 0 0 1 1 1 0 Pupal cuticle protein C1 DUF4446 PF14584.1 CCV00044.1 - 0.65 9.8 4.8 13 5.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) EphA2_TM PF14575.1 CCV00044.1 - 0.96 9.8 10.0 9.4 6.7 0.0 4.2 5 0 0 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain ICMT PF04140.9 CCV00046.1 - 3.2e-27 94.5 1.3 4.5e-27 94.0 0.9 1.2 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCV00046.1 - 4.9e-13 49.0 1.9 6.9e-13 48.6 1.3 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 CCV00046.1 - 0.00018 20.8 0.8 0.00021 20.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Amidohydro_2 PF04909.9 CCV00047.1 - 8.5e-11 41.9 3.9 1.1e-10 41.5 1.8 2.0 1 1 1 2 2 2 1 Amidohydrolase ADK PF00406.17 CCV00049.1 - 3.3e-58 195.8 0.1 4.1e-58 195.5 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CCV00049.1 - 9.1e-14 50.8 0.0 2.3e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CCV00049.1 - 2.3e-07 30.7 0.0 4.3e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCV00049.1 - 1.8e-05 23.9 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 CCV00049.1 - 0.00036 21.3 0.0 0.00074 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCV00049.1 - 0.0038 17.5 0.0 0.0097 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CCV00049.1 - 0.02 15.0 0.0 0.046 13.9 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 CCV00049.1 - 0.02 14.2 0.1 3.3 7.0 0.0 2.7 2 1 1 3 3 3 0 Thymidylate kinase Guanylate_kin PF00625.16 CCV00049.1 - 0.058 12.8 0.1 12 5.2 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase AAA_5 PF07728.9 CCV00049.1 - 0.06 13.0 0.1 0.21 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ParA PF10609.4 CCV00050.1 - 6.6e-30 102.8 0.0 9.8e-30 102.2 0.0 1.2 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCV00050.1 - 1.5e-10 40.8 0.1 4.6e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 CCV00050.1 - 4.2e-05 22.7 2.2 0.00044 19.3 0.3 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 CCV00050.1 - 5.7e-05 22.5 0.0 9.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 CCV00050.1 - 8.2e-05 22.5 0.0 0.001 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 CCV00050.1 - 0.006 15.6 0.0 0.031 13.3 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ AAA_19 PF13245.1 CCV00050.1 - 0.033 13.9 0.6 2.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain DUF258 PF03193.11 CCV00050.1 - 0.048 12.8 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Cache_3 PF14827.1 CCV00050.1 - 0.066 13.1 0.1 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 Sensory domain of two-component sensor kinase AAA_22 PF13401.1 CCV00050.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_11 PF13414.1 CCV00051.1 - 4.7e-22 77.4 32.0 6.7e-09 35.2 0.2 8.5 6 2 4 10 10 10 8 TPR repeat TPR_1 PF00515.23 CCV00051.1 - 9.2e-19 66.2 15.4 0.0019 17.7 0.1 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 CCV00051.1 - 2.4e-17 61.3 39.3 0.0012 18.5 0.0 10.3 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 CCV00051.1 - 8.5e-12 45.4 61.3 4.3e-07 30.4 2.3 9.8 5 2 7 12 12 12 8 Tetratricopeptide repeat TPR_8 PF13181.1 CCV00051.1 - 1.6e-11 43.0 3.4 0.082 12.7 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCV00051.1 - 9.3e-11 41.3 60.4 0.00018 21.8 0.4 11.4 7 3 5 12 12 12 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCV00051.1 - 1.3e-10 41.0 31.2 1e-06 28.5 0.4 7.4 5 1 3 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCV00051.1 - 1.2e-07 31.3 15.2 2.4 8.5 0.1 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCV00051.1 - 2.2e-06 27.0 22.1 0.14 12.0 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCV00051.1 - 7.6e-05 22.9 38.7 0.29 11.4 0.2 8.5 7 2 1 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCV00051.1 - 9.1e-05 22.6 25.3 0.019 15.3 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CCV00051.1 - 0.00057 19.9 26.3 0.24 11.5 0.0 6.7 6 2 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF384 PF04064.8 CCV00051.1 - 0.12 11.9 0.0 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF384) RNase_H2-Ydr279 PF09468.5 CCV00053.1 - 2e-16 60.0 0.0 2.9e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF455 PF04305.9 CCV00054.1 - 4.6e-84 281.6 0.0 5.6e-84 281.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) 2Fe-2S_thioredx PF01257.14 CCV00056.1 - 8.9e-54 181.0 1.1 1.2e-53 180.6 0.8 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.6 CCV00056.1 - 0.0031 17.7 0.1 0.0052 17.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1636) adh_short PF00106.20 CCV00057.1 - 1.3e-09 38.2 8.1 7.7e-06 25.9 2.5 2.4 1 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCV00057.1 - 3.9e-06 26.6 2.5 0.00015 21.4 0.7 2.4 2 0 0 2 2 2 2 KR domain RNA_polI_A34 PF08208.6 CCV00058.1 - 1.4e-06 28.1 3.2 0.0016 18.1 0.0 2.3 2 0 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 GST_C_2 PF13410.1 CCV00059.1 - 0.0055 16.5 0.2 0.0055 16.5 0.2 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCV00059.1 - 0.0092 16.4 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1g PF09334.6 CCV00061.1 - 1.5e-104 349.8 0.0 2.3e-104 349.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CCV00061.1 - 7.6e-18 63.8 0.1 1.6e-09 36.3 0.0 2.7 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CCV00061.1 - 1.3e-08 34.3 0.0 0.0041 16.2 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 CCV00061.1 - 0.0026 17.5 0.1 0.0053 16.5 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.13 CCV00061.1 - 0.0096 14.6 0.0 0.015 13.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) Peptidase_C28 PF05408.6 CCV00061.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase ApbA PF02558.11 CCV00062.1 - 1.1e-30 106.0 0.0 1.5e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 CCV00062.1 - 1.6e-23 83.0 0.0 2.9e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_7 PF13241.1 CCV00062.1 - 0.023 14.9 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding tRNA-synt_2 PF00152.15 CCV00063.1 - 1.4e-77 260.7 0.1 1.4e-77 260.7 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 CCV00063.1 - 3.6e-17 62.1 0.3 6.6e-17 61.2 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2156) tRNA-synt_2d PF01409.15 CCV00063.1 - 5.6e-05 22.4 0.2 0.056 12.6 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 CCV00063.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Synaptobrevin PF00957.16 CCV00064.1 - 3.1e-23 81.1 0.0 3.9e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CCV00064.1 - 1.7e-17 62.7 0.0 2.7e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF1839 PF08893.5 CCV00064.1 - 0.072 12.0 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) Hemerythrin PF01814.18 CCV00064.1 - 0.13 12.3 0.6 0.71 10.0 0.0 2.3 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain Snf7 PF03357.16 CCV00065.1 - 2.1e-13 49.9 3.3 3.3e-13 49.3 2.3 1.3 1 0 0 1 1 1 1 Snf7 DUF677 PF05055.7 CCV00065.1 - 0.094 11.3 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) TPR_MLP1_2 PF07926.7 CCV00065.1 - 1.6 8.4 5.4 5.2 6.8 0.7 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Mnd1 PF03962.10 CCV00065.1 - 2 8.0 4.9 0.69 9.5 1.5 1.5 2 0 0 2 2 2 0 Mnd1 family Cortex-I_coil PF09304.5 CCV00065.1 - 3.5 7.7 6.2 0.65 10.0 0.5 2.6 4 0 0 4 4 4 0 Cortexillin I, coiled coil OB_NTP_bind PF07717.11 CCV00066.1 - 1.9e-20 72.8 0.1 4.9e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CCV00066.1 - 5.5e-19 68.0 0.1 1.1e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCV00066.1 - 5.9e-12 45.2 0.0 9.9e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCV00066.1 - 0.00096 18.6 0.0 0.0022 17.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3798 PF12683.2 CCV00066.1 - 0.059 12.4 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) SCA7 PF08313.7 CCV00067.1 - 5.8e-29 99.5 0.1 1.4e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 SCA7, zinc-binding domain adh_short PF00106.20 CCV00068.1 - 0.013 15.3 1.8 0.11 12.3 0.1 2.6 2 1 1 3 3 3 0 short chain dehydrogenase DASH_Dad2 PF08654.5 CCV00069.1 - 1.7e-21 76.1 0.8 2.2e-21 75.7 0.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DUF3418 PF11898.3 CCV00069.1 - 0.0042 15.5 0.4 0.0047 15.3 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) DUF550 PF04447.7 CCV00069.1 - 0.052 13.1 0.1 0.07 12.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF550) ApbA PF02558.11 CCV00069.1 - 0.056 12.8 0.1 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HrpB7 PF09486.5 CCV00069.1 - 0.14 12.1 5.7 0.22 11.4 4.0 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF21 PF01595.15 CCV00069.1 - 0.18 11.0 2.0 0.3 10.3 1.2 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF21 Ribosomal_S30 PF04758.9 CCV00070.1 - 9.9e-31 105.2 6.7 1.1e-30 105.1 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 zf-Tim10_DDP PF02953.10 CCV00072.1 - 3.5e-21 74.2 0.9 3.9e-21 74.0 0.6 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Asp PF00026.18 CCV00073.2 - 6.8e-71 239.1 1.0 8.3e-71 238.8 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCV00073.2 - 5.7e-08 32.8 0.4 1.8e-07 31.2 0.1 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal DnaJ PF00226.26 CCV00074.1 - 2.3e-22 78.5 0.7 3.8e-22 77.7 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCV00074.1 - 7.4e-21 73.8 0.0 2.6e-17 62.4 0.0 2.6 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCV00074.1 - 2.8e-15 56.0 13.1 4.5e-15 55.4 9.1 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CCV00074.1 - 0.012 15.2 2.9 0.92 9.2 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrome_C554 PF13435.1 CCV00074.1 - 0.022 14.8 4.5 0.059 13.4 3.1 1.7 1 0 0 1 1 1 0 Cytochrome c554 and c-prime A2L_zn_ribbon PF08792.5 CCV00074.1 - 1.2 8.7 3.9 13 5.3 0.0 3.0 3 0 0 3 3 3 0 A2L zinc ribbon domain Antiterm PF03589.8 CCV00074.1 - 1.5 8.9 4.4 21 5.2 3.1 2.4 1 1 0 1 1 1 0 Antitermination protein DZR PF12773.2 CCV00074.1 - 2.3 8.1 11.7 6.7 6.6 1.9 2.3 1 1 2 3 3 3 0 Double zinc ribbon zf-RING_3 PF14369.1 CCV00074.1 - 4.1 7.4 11.8 13 5.8 0.1 3.9 3 1 1 4 4 4 0 zinc-finger FA_hydroxylase PF04116.8 CCV00075.1 - 1.7e-16 60.6 12.6 1.7e-16 60.6 8.7 2.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Mur_ligase PF01225.20 CCV00075.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Response_reg PF00072.19 CCV00076.1 - 8e-23 80.5 0.2 5e-16 58.7 0.1 3.0 3 0 0 3 3 3 2 Response regulator receiver domain NCA2 PF08637.5 CCV00077.1 - 4.6e-53 179.9 0.0 6.4e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 NMT PF01233.14 CCV00078.1 - 2.4e-74 248.3 0.0 3.4e-74 247.8 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 CCV00078.1 - 2.2e-65 219.6 0.0 3.8e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 CCV00078.1 - 2.9e-06 27.1 0.0 2.7e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCV00078.1 - 0.011 15.8 0.0 0.054 13.5 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCV00078.1 - 0.063 13.4 0.1 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-CCCH PF00642.19 CCV00079.1 - 0.00037 20.0 1.0 0.00037 20.0 0.7 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FYVE PF01363.16 CCV00079.1 - 0.0035 17.1 0.3 0.0035 17.1 0.2 1.6 2 0 0 2 2 2 1 FYVE zinc finger zf-CCCH_2 PF14608.1 CCV00079.1 - 0.062 13.3 1.9 0.17 11.9 1.3 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUF2256 PF10013.4 CCV00079.1 - 0.076 12.7 0.4 0.076 12.7 0.3 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Complex1_LYR_1 PF13232.1 CCV00080.1 - 1.7e-07 31.3 0.2 4.1e-07 30.0 0.2 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CCV00080.1 - 5.4e-07 29.3 0.1 1e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ribosomal_L31 PF01197.13 CCV00080.1 - 0.047 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L31 HECT PF00632.20 CCV00081.1 - 3e-92 309.1 0.0 3.9e-92 308.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CCV00081.1 - 5e-32 109.3 19.4 8e-11 41.5 0.2 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.25 CCV00081.1 - 1.3e-12 47.4 0.3 3.4e-12 46.0 0.2 1.7 1 0 0 1 1 1 1 C2 domain Nuc_sug_transp PF04142.10 CCV00082.1 - 1.2e-11 44.2 6.5 1.6e-11 43.7 4.5 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 CCV00082.1 - 1.9e-05 23.7 8.5 2.8e-05 23.1 5.9 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CCV00082.1 - 0.0042 17.1 4.5 0.0042 17.1 3.1 3.0 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 CCV00082.1 - 0.0094 16.1 7.1 0.0094 16.1 4.9 2.6 2 1 0 2 2 2 1 Multidrug resistance efflux transporter Hist_deacetyl PF00850.14 CCV00083.1 - 6.2e-78 262.2 0.0 7.9e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Polysacc_deac_1 PF01522.16 CCV00084.1 - 9.3e-61 202.9 0.0 1.3e-30 105.5 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide deacetylase Serglycin PF04360.7 CCV00084.1 - 0.0017 18.1 3.6 0.011 15.4 0.1 2.6 2 0 0 2 2 2 1 Serglycin VPEP PF07589.6 CCV00084.1 - 0.036 13.9 0.2 7 6.7 0.1 3.1 2 0 0 2 2 2 0 PEP-CTERM motif Mitofilin PF09731.4 CCV00084.1 - 0.2 10.2 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein WD40 PF00400.27 CCV00085.1 - 3.3e-10 39.4 3.9 0.004 16.9 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1214 PF06742.6 CCV00086.1 - 5.1e-15 55.8 3.0 3.7e-08 33.7 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1214) Big_3_4 PF13754.1 CCV00086.1 - 0.0046 17.2 0.8 3.2 8.1 0.1 3.0 2 1 0 2 2 2 2 Bacterial Ig-like domain (group 3) Y_Y_Y PF07495.8 CCV00086.1 - 0.097 12.4 5.0 6.6 6.5 0.1 4.2 3 2 0 3 3 3 0 Y_Y_Y domain Ribosomal_L30 PF00327.15 CCV00087.1 - 3.1e-12 45.8 0.2 4.1e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Exo_endo_phos PF03372.18 CCV00090.1 - 6.9e-05 22.9 0.0 7.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DEAD PF00270.24 CCV00091.1 - 7.2e-46 155.7 0.0 3.5e-45 153.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCV00091.1 - 7.9e-18 64.1 0.0 3.2e-17 62.1 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCV00091.1 - 9.7e-05 22.2 0.0 0.00055 19.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CCV00091.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Pkinase PF00069.20 CCV00092.1 - 5.1e-20 71.7 1.8 6.8e-08 31.9 0.0 3.1 1 1 2 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CCV00092.1 - 3.9e-08 32.6 0.4 0.0021 17.1 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CCV00092.1 - 0.015 14.0 0.1 0.024 13.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 CCV00092.1 - 0.052 12.8 0.3 5.5 6.2 0.0 2.2 1 1 0 2 2 2 0 RIO1 family APH PF01636.18 CCV00092.1 - 0.053 13.2 0.2 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family TBCA PF02970.11 CCV00093.1 - 1.4e-19 69.9 0.6 1.4e-19 69.9 0.4 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A PMEI PF04043.10 CCV00093.1 - 0.012 15.5 0.1 0.012 15.5 0.1 1.1 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Plasmodium_HRP PF05403.6 CCV00094.1 - 0.015 14.9 70.9 0.025 14.1 49.1 1.2 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) DUF605 PF04652.11 CCV00094.1 - 0.018 14.4 65.5 0.0073 15.7 32.6 2.4 2 0 0 2 2 2 0 Vta1 like Lip_prot_lig_C PF10437.4 CCV00094.1 - 0.11 12.1 0.1 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus FAM196 PF15265.1 CCV00094.1 - 3.6 6.7 66.6 2.4 7.2 36.8 2.1 2 0 0 2 2 2 0 FAM196 family Asp PF00026.18 CCV00095.1 - 1.5e-108 362.7 0.0 1.8e-108 362.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCV00095.1 - 1.9e-09 37.7 0.0 4.3e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCV00095.1 - 3.9e-08 33.0 0.0 6.2e-07 29.0 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CCV00095.1 - 0.0011 19.4 0.0 0.18 12.3 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease G-patch_2 PF12656.2 CCV00096.1 - 4.6e-29 100.0 0.1 1.3e-28 98.6 0.1 1.8 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 CCV00096.1 - 2.8e-08 33.4 1.4 5.3e-08 32.5 0.9 1.5 1 0 0 1 1 1 1 G-patch domain Methyltransf_12 PF08242.7 CCV00097.1 - 0.0023 18.3 0.0 0.0036 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCV00097.1 - 0.0026 18.3 0.0 0.046 14.3 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCV00097.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.24 CCV00098.1 - 1.7e-36 125.2 0.1 4.4e-36 123.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCV00098.1 - 1.9e-25 88.5 0.0 2.2e-24 85.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCV00098.1 - 2.3e-06 27.5 0.0 5.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CCV00098.1 - 0.029 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Sod_Fe_C PF02777.13 CCV00099.1 - 9e-34 115.5 2.4 1.6e-33 114.6 1.7 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CCV00099.1 - 2.2e-31 107.9 2.9 2.2e-31 107.9 2.0 1.7 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, alpha-hairpin domain G6PD_C PF02781.11 CCV00100.1 - 1.3e-114 381.9 0.0 1.8e-114 381.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CCV00100.1 - 1.7e-49 168.5 0.0 2.9e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain zf-H2C2_2 PF13465.1 CCV00101.1 - 6.8e-10 38.7 17.3 1.6e-06 28.0 3.2 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CCV00101.1 - 2.3e-08 33.8 12.1 0.00015 21.9 1.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCV00101.1 - 1.5e-05 24.9 12.1 0.0056 16.9 1.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 CCV00101.1 - 0.36 10.9 3.6 0.66 10.1 2.5 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CCV00101.1 - 0.84 9.8 6.3 8.8 6.6 0.1 3.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Leo1 PF04004.8 CCV00102.1 - 1.7e-50 171.0 0.0 1.7e-50 171.0 0.0 2.1 3 0 0 3 3 3 1 Leo1-like protein Ebp2 PF05890.7 CCV00103.1 - 2e-79 266.7 20.3 2e-79 266.7 14.1 2.6 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF747 PF05346.6 CCV00105.1 - 3.1e-113 378.2 6.2 4.3e-113 377.7 4.3 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family N2227 PF07942.7 CCV00106.1 - 9.1e-88 293.7 0.0 1.1e-87 293.4 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein BHD_3 PF10405.4 CCV00107.1 - 1.6e-23 82.1 0.0 2.9e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 CCV00107.1 - 2.6e-23 82.0 0.1 5.7e-23 80.9 0.1 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 CCV00107.1 - 2.7e-17 62.0 0.5 7.6e-17 60.5 0.0 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CCV00107.1 - 4.3e-13 49.3 1.3 7.1e-13 48.6 0.1 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 CCV00107.1 - 2.4e-10 40.6 0.9 5.4e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily Zn_clus PF00172.13 CCV00108.1 - 0.0003 20.6 13.9 0.00069 19.4 9.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexokinase_2 PF03727.11 CCV00108.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Hexokinase Pkinase PF00069.20 CCV00109.1 - 1.2e-67 227.8 0.0 1.4e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCV00109.1 - 1.7e-34 119.0 0.0 2.5e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCV00109.1 - 5.2e-06 25.6 0.0 1.7e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCV00109.1 - 0.0091 15.7 8.0 0.1 12.2 0.2 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family PLAC9 PF15205.1 CCV00110.1 - 0.095 12.9 0.3 5.2 7.4 0.0 3.0 2 1 1 3 3 3 0 Placenta-specific protein 9 NPV_P10 PF05531.7 CCV00110.1 - 0.52 10.5 4.7 2.8 8.2 0.1 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 CCV00110.1 - 0.57 10.0 4.6 5.5 6.9 0.1 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.17 CCV00110.1 - 0.97 9.4 34.0 0.43 10.6 7.7 4.4 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.7 CCV00110.1 - 9.2 6.0 6.3 63 3.3 1.1 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Kinesin PF00225.18 CCV00111.1 - 1.9e-69 233.9 0.0 1.1e-68 231.4 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain TMF_DNA_bd PF12329.3 CCV00111.1 - 1.2 8.9 6.7 12 5.7 4.6 2.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Nup54 PF13874.1 CCV00111.1 - 1.6 8.3 11.9 4.6 6.8 8.2 1.8 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 zf-Apc11 PF12861.2 CCV00112.1 - 6e-24 83.7 9.8 7.5e-24 83.3 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CCV00112.1 - 9.2e-22 76.9 10.1 1.3e-21 76.4 7.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCV00112.1 - 3.7e-07 29.8 14.3 1.6e-06 27.7 9.9 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCV00112.1 - 2.7e-05 23.7 10.4 6.8e-05 22.4 7.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCV00112.1 - 0.00028 20.8 9.2 0.0034 17.3 6.4 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCV00112.1 - 0.026 14.2 7.2 0.026 14.2 5.0 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.6 CCV00112.1 - 0.033 14.1 6.6 0.033 14.1 4.6 2.3 2 1 0 2 2 2 0 RING-like domain zf-HC5HC2H PF13771.1 CCV00112.1 - 0.036 14.2 7.0 0.1 12.7 5.1 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.1 CCV00112.1 - 0.039 13.8 9.9 1.8 8.5 6.9 2.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CCV00112.1 - 0.051 13.2 11.3 0.45 10.2 7.3 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CCV00112.1 - 0.065 13.2 11.7 0.53 10.2 8.1 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 CCV00112.1 - 0.23 11.4 7.3 0.45 10.5 5.1 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-Nse PF11789.3 CCV00112.1 - 0.55 9.7 6.8 0.92 9.0 4.7 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 CCV00112.1 - 0.6 10.2 11.2 0.15 12.0 4.9 2.1 2 1 0 2 2 2 0 RING-variant domain Rad50_zn_hook PF04423.9 CCV00112.1 - 0.65 9.4 0.0 0.65 9.4 0.0 2.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_4 PF14570.1 CCV00112.1 - 2.5 7.7 13.7 9.5 5.9 6.7 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain RecR PF02132.10 CCV00112.1 - 6.4 6.3 6.6 6.8 6.2 0.3 3.0 2 1 1 3 3 3 0 RecR protein AMPKBI PF04739.10 CCV00113.1 - 2.1e-26 91.7 3.7 4.3e-26 90.7 0.0 2.7 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain Methyltransf_23 PF13489.1 CCV00114.1 - 1.8e-11 44.0 0.0 2.3e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCV00114.1 - 3.7e-09 36.9 0.0 1.1e-08 35.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCV00114.1 - 6.5e-09 36.1 0.0 2e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCV00114.1 - 2.5e-08 34.4 0.1 3.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCV00114.1 - 0.00018 21.5 2.9 0.0016 18.4 2.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCV00114.1 - 0.00045 19.8 0.0 0.0079 15.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCV00114.1 - 0.0019 18.5 0.0 0.0043 17.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CCV00114.1 - 0.0057 17.4 0.1 0.0081 16.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 CCV00114.1 - 0.02 14.7 2.5 0.025 14.4 1.7 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3369 PF11849.3 CCV00114.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) HAD_2 PF13419.1 CCV00115.1 - 1.1e-14 55.0 0.0 1.9e-14 54.2 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCV00115.1 - 2.2e-10 41.2 0.0 3.8e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCV00115.1 - 3.1e-07 29.9 0.0 5.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CCV00115.1 - 0.00016 21.9 0.0 0.00021 21.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase tRNA-synt_1_2 PF13603.1 CCV00115.1 - 0.018 14.3 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 HAD_2 PF13419.1 CCV00116.1 - 8.3e-10 39.1 0.0 1.9e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCV00116.1 - 3.2e-09 36.3 0.1 1e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 CCV00116.1 - 0.00011 22.7 0.0 0.00038 20.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ubiquitin PF00240.18 CCV00117.1 - 4.1e-14 51.7 0.1 6.9e-14 50.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCV00117.1 - 7.7e-07 28.7 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 CCV00117.1 - 1.2e-05 25.0 0.1 1.2e-05 25.0 0.0 2.3 3 0 0 3 3 3 1 UBA/TS-N domain DUF2407 PF10302.4 CCV00117.1 - 0.0017 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Put_Phosphatase PF06888.7 CCV00117.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative Phosphatase Proteasome PF00227.21 CCV00118.1 - 2e-20 72.9 0.0 4.4e-20 71.7 0.0 1.5 2 0 0 2 2 2 1 Proteasome subunit Metallophos PF00149.23 CCV00119.1 - 2.2e-41 141.4 1.9 3.3e-41 140.8 1.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2413 PF10310.4 CCV00120.1 - 9e-16 57.7 4.3 1.5e-15 56.9 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Ribosomal_L19e PF01280.15 CCV00121.1 - 3.1e-62 208.7 11.8 3.1e-62 208.7 8.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e TFIIS_M PF07500.9 CCV00121.1 - 0.15 12.1 5.8 0.061 13.3 2.5 1.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain Methyltransf_31 PF13847.1 CCV00122.1 - 8.5e-10 38.4 0.0 1.9e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ribosomal_S8 PF00410.14 CCV00122.1 - 2.5e-09 37.0 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S8 Methyltransf_18 PF12847.2 CCV00122.1 - 5.4e-08 33.4 0.0 1.5e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCV00122.1 - 1.6e-05 25.3 0.0 3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCV00122.1 - 0.00011 22.2 0.0 0.00018 21.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCV00122.1 - 0.00083 19.0 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MDMPI_C PF07398.6 CCV00122.1 - 0.007 16.9 0.1 0.014 15.9 0.1 1.4 1 0 0 1 1 1 1 MDMPI C-terminal domain Methyltransf_25 PF13649.1 CCV00122.1 - 0.03 14.6 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CCV00122.1 - 0.045 13.1 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 CCV00122.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ATP-grasp_2 PF08442.5 CCV00123.1 - 1.3e-72 243.4 0.6 1.9e-72 242.9 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 CCV00123.1 - 2.8e-23 82.2 0.8 6.6e-23 80.9 0.6 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 CCV00123.1 - 2.7e-14 52.9 0.4 1.1e-13 50.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 CCV00123.1 - 6.9e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CCV00123.1 - 0.00019 20.8 0.1 0.00043 19.6 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 CCV00123.1 - 0.0016 17.9 1.1 0.0045 16.5 0.1 2.1 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.17 CCV00123.1 - 0.0074 15.6 0.1 0.025 13.9 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CCV00123.1 - 0.01 15.3 0.0 0.033 13.6 0.0 1.9 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Rrp15p PF07890.7 CCV00124.1 - 1.3e-12 47.9 3.4 1.3e-12 47.9 2.3 2.3 1 1 1 2 2 2 1 Rrp15p Nop14 PF04147.7 CCV00124.1 - 0.24 9.2 14.3 0.31 8.8 9.9 1.3 1 0 0 1 1 1 0 Nop14-like family BCAS2 PF05700.6 CCV00125.1 - 3.6e-43 147.5 2.8 4.7e-43 147.2 1.9 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Complex1_30kDa PF00329.14 CCV00126.1 - 2.6e-35 120.7 0.0 3.5e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit SGT1 PF07093.6 CCV00127.1 - 7.1e-104 348.2 0.0 1e-103 347.7 0.0 1.1 1 0 0 1 1 1 1 SGT1 protein TEX19 PF15553.1 CCV00127.1 - 0.35 10.7 4.2 0.2 11.5 0.9 2.1 1 1 1 2 2 2 0 Testis-expressed protein 19 Peptidase_C48 PF02902.14 CCV00128.1 - 6.9e-34 117.3 0.0 1.2e-33 116.5 0.0 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LCAT PF02450.10 CCV00129.1 - 2.6e-75 253.8 0.1 3.8e-75 253.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase TGS PF02824.16 CCV00129.1 - 3.8e-17 61.8 0.1 8.1e-17 60.8 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CCV00129.1 - 1.6e-16 60.2 0.0 3.5e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCV00129.1 - 1.2e-09 37.6 0.0 2.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Abhydrolase_6 PF12697.2 CCV00129.1 - 8.8e-06 25.7 0.8 4.1e-05 23.5 0.0 2.6 4 1 0 4 4 4 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCV00129.1 - 7.8e-05 22.4 0.1 0.00025 20.8 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Miro PF08477.8 CCV00129.1 - 0.0015 19.0 0.0 0.0041 17.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein PGAP1 PF07819.8 CCV00129.1 - 0.012 15.2 0.1 0.043 13.3 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Dynamin_N PF00350.18 CCV00129.1 - 0.037 13.8 0.2 3.6 7.3 0.0 2.3 1 1 1 2 2 2 0 Dynamin family AAA_28 PF13521.1 CCV00129.1 - 0.048 13.6 0.4 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 AAA domain CBS PF00571.23 CCV00130.1 - 2.6e-10 39.9 0.0 3.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 CBS domain CBS PF00571.23 CCV00131.1 - 1.4e-23 82.3 4.2 1.7e-08 34.1 0.5 3.6 3 0 0 3 3 3 3 CBS domain PB1 PF00564.19 CCV00131.1 - 0.0019 17.7 0.4 0.0051 16.4 0.2 1.6 1 0 0 1 1 1 1 PB1 domain Acyl-CoA_dh_1 PF00441.19 CCV00132.1 - 3.6e-40 137.5 2.4 5.7e-40 136.8 1.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CCV00132.1 - 2.9e-25 89.0 0.2 6.1e-25 87.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CCV00132.1 - 2.9e-24 84.3 0.5 6.9e-24 83.1 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CCV00132.1 - 3.8e-15 56.3 2.2 8e-15 55.2 1.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CCV00132.1 - 0.00042 19.7 0.0 0.0015 18.0 0.0 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal SUR7 PF06687.7 CCV00133.1 - 8.2e-21 74.5 3.1 1e-20 74.2 2.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family Aa_trans PF01490.13 CCV00133.1 - 0.0021 16.6 1.4 0.0036 15.8 1.0 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NADH5_C PF06455.6 CCV00133.1 - 0.015 14.6 0.5 0.015 14.6 0.4 1.5 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus Peptidase_U4 PF03419.8 CCV00133.1 - 0.092 11.8 2.4 0.17 10.9 1.6 1.5 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF373 PF04123.8 CCV00133.1 - 0.47 9.4 7.7 0.32 9.9 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Claudin_2 PF13903.1 CCV00133.1 - 0.52 9.9 15.1 0.73 9.5 7.5 2.6 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DoxX PF07681.7 CCV00133.1 - 8.9 6.8 19.0 1 9.8 5.7 2.8 2 1 1 3 3 3 0 DoxX CorA PF01544.13 CCV00134.1 - 4.5e-45 153.9 0.9 6.2e-45 153.4 0.6 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ACT_4 PF13291.1 CCV00134.1 - 0.026 14.8 0.2 0.081 13.2 0.1 1.8 2 0 0 2 2 2 0 ACT domain DUF3826 PF12875.2 CCV00134.1 - 0.07 12.8 0.3 2.4 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) Mannosyl_trans PF05007.8 CCV00135.1 - 1.1e-47 162.9 9.9 4.8e-39 134.5 0.0 2.8 2 1 1 3 3 3 2 Mannosyltransferase (PIG-M) Sugar_tr PF00083.19 CCV00138.1 - 5.2e-98 328.5 11.3 6.3e-98 328.2 7.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCV00138.1 - 4.1e-10 38.9 12.8 4.1e-10 38.9 8.8 3.5 3 2 1 4 4 4 2 Major Facilitator Superfamily DPBB_1 PF03330.13 CCV00139.1 - 6.5e-05 22.8 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF605 PF04652.11 CCV00139.1 - 0.0077 15.6 27.7 0.012 15.0 19.2 1.3 1 0 0 1 1 1 1 Vta1 like Rib_hydrolayse PF02267.12 CCV00139.1 - 0.015 14.6 0.1 0.015 14.6 0.1 2.1 2 1 1 3 3 3 0 ADP-ribosyl cyclase DUF936 PF06075.7 CCV00139.1 - 0.59 8.9 35.0 0.71 8.7 24.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) PLRV_ORF5 PF01690.12 CCV00139.1 - 0.75 8.8 19.7 0.95 8.5 13.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Hydantoinase_B PF02538.9 CCV00140.1 - 1.5e-186 620.7 0.0 3.8e-186 619.3 0.0 1.5 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Pkinase PF00069.20 CCV00141.1 - 3.5e-67 226.2 0.0 5e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCV00141.1 - 1.3e-46 158.8 0.0 1.9e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 CCV00141.1 - 1.2e-18 66.9 0.0 3e-18 65.6 0.0 1.6 2 0 0 2 2 2 1 Ras-binding domain of Byr2 Kinase-like PF14531.1 CCV00141.1 - 1.5e-06 27.4 0.2 1.4e-05 24.2 0.0 2.3 2 1 0 2 2 2 1 Kinase-like RA PF00788.18 CCV00141.1 - 0.00063 20.1 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 CCV00141.1 - 0.031 13.3 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family E1-E2_ATPase PF00122.15 CCV00142.1 - 8.1e-22 77.3 0.0 2e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCV00142.1 - 4e-21 76.4 0.0 1.2e-19 71.5 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCV00142.1 - 1.3e-18 67.8 0.0 2.7e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCV00142.1 - 0.0012 18.7 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCV00142.1 - 0.014 15.0 0.2 0.035 13.7 0.1 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Mito_carr PF00153.22 CCV00143.1 - 2.2e-55 184.3 0.1 2.4e-19 68.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RIC1 PF07064.8 CCV00144.1 - 1.1e-42 146.2 0.1 1.8e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 RIC1 Pkinase PF00069.20 CCV00145.1 - 2.3e-64 217.0 0.0 4e-64 216.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCV00145.1 - 2.7e-35 121.6 0.0 5.2e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCV00145.1 - 6.6e-07 28.5 0.0 1.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CCV00145.1 - 0.00036 19.4 0.1 0.0006 18.7 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Arylesterase PF01731.15 CCV00146.1 - 0.024 14.5 0.0 0.12 12.3 0.0 2.3 3 0 0 3 3 3 0 Arylesterase Longin PF13774.1 CCV00147.1 - 6.2e-14 51.3 0.0 1.1e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CCV00147.1 - 1.2e-11 43.9 0.9 2.7e-11 42.8 0.6 1.6 1 0 0 1 1 1 1 Synaptobrevin Herpes_teg_N PF04843.7 CCV00147.1 - 0.1 11.9 0.1 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Beta-lactamase PF00144.19 CCV00147.1 - 0.11 11.5 0.1 0.48 9.3 0.1 1.9 1 1 0 1 1 1 0 Beta-lactamase COPIIcoated_ERV PF07970.7 CCV00147.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter PHD PF00628.24 CCV00148.1 - 8.3e-11 41.4 22.3 1.6e-05 24.5 0.3 3.5 3 1 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 CCV00148.1 - 0.92 8.7 6.5 3.5 6.9 2.0 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 CCV00148.1 - 1.4 8.2 10.4 0.32 10.3 0.1 3.5 3 0 0 3 3 3 0 PHD-finger Spc7 PF08317.6 CCV00149.1 - 0.0018 16.9 1.2 0.0018 16.9 0.8 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein SLS PF14611.1 CCV00149.1 - 0.029 13.8 1.0 0.053 12.9 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator GAS PF13851.1 CCV00149.1 - 0.16 11.1 9.6 0.58 9.3 0.7 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Lipoprotein_20 PF13942.1 CCV00149.1 - 0.34 10.4 6.7 0.83 9.1 0.1 2.4 1 1 1 2 2 2 0 YfhG lipoprotein DUF724 PF05266.9 CCV00149.1 - 1.1 8.8 6.9 0.39 10.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DivIC PF04977.10 CCV00149.1 - 1.2 8.6 6.7 4.9 6.7 0.3 3.1 3 0 0 3 3 3 0 Septum formation initiator RPA_interact_M PF14767.1 CCV00149.1 - 3.5 8.4 10.7 13 6.6 3.7 3.2 2 1 0 2 2 2 0 Replication protein A interacting middle Atg14 PF10186.4 CCV00149.1 - 4.8 6.0 9.0 0.43 9.4 0.8 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 CCV00149.1 - 7.4 6.9 6.8 37 4.7 1.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) 2-oxoacid_dh PF00198.18 CCV00150.1 - 5.7e-80 267.8 0.1 8.3e-80 267.3 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CCV00150.1 - 3.8e-20 71.2 3.8 9.4e-20 70.0 2.6 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CCV00150.1 - 0.0051 16.4 0.1 0.037 13.6 0.0 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 CCV00150.1 - 0.012 14.7 8.6 0.017 14.3 2.8 2.2 1 1 1 2 2 2 0 HlyD family secretion protein YL1 PF05764.8 CCV00150.1 - 0.025 14.1 22.3 0.038 13.5 15.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF4370 PF14290.1 CCV00150.1 - 0.046 13.1 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) BASP1 PF05466.7 CCV00150.1 - 0.048 13.4 34.1 0.087 12.6 23.7 1.4 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) HlyD_3 PF13437.1 CCV00150.1 - 0.057 13.7 0.2 7.9 6.8 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein CDC45 PF02724.9 CCV00150.1 - 0.094 10.7 9.3 0.11 10.4 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein MIP-T3 PF10243.4 CCV00150.1 - 0.13 10.6 30.8 0.18 10.2 21.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 CCV00150.1 - 0.38 10.0 17.8 0.65 9.3 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SelP_N PF04592.9 CCV00150.1 - 5.7 6.2 6.7 9 5.5 4.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region GAGA_bind PF06217.7 CCV00150.1 - 6 6.7 9.9 9.7 6.0 6.8 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.11 CCV00150.1 - 8.9 6.1 7.1 14 5.4 4.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mito_carr PF00153.22 CCV00151.1 - 2.6e-56 187.3 1.1 2.1e-19 69.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 CCV00152.1 - 1.3e-63 214.5 0.0 1.6e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCV00152.1 - 2.4e-38 131.7 0.0 3.7e-38 131.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCV00152.1 - 0.00024 20.1 0.0 0.00042 19.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SQS_PSY PF00494.14 CCV00153.1 - 2.5e-40 138.4 0.1 3.2e-40 138.1 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase ORC2 PF04084.9 CCV00154.1 - 5.4e-39 133.9 0.0 7.3e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Cluap1 PF10234.4 CCV00154.1 - 0.061 12.5 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Motile_Sperm PF00635.21 CCV00155.1 - 1.2e-25 89.2 0.1 2.4e-25 88.2 0.1 1.5 1 1 0 1 1 1 1 MSP (Major sperm protein) domain CDC48_2 PF02933.12 CCV00155.1 - 0.14 11.8 0.1 0.76 9.4 0.1 2.0 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 4HBT_3 PF13622.1 CCV00156.1 - 1.2e-35 123.4 6.3 1.5e-35 123.1 4.4 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 CCV00156.1 - 0.0033 17.0 0.1 0.0079 15.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA thioesterase VirB8 PF04335.8 CCV00156.1 - 0.051 13.1 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 VirB8 protein ATP-synt_ab PF00006.20 CCV00157.1 - 1.3e-61 207.8 0.0 1.8e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCV00157.1 - 1e-18 67.8 0.1 2.1e-18 66.8 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCV00157.1 - 3.6e-11 43.1 0.3 8e-11 41.9 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CCV00157.1 - 0.0002 21.2 0.1 0.0004 20.2 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain DUF561 PF04481.7 CCV00157.1 - 0.077 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Ribosomal_L28 PF00830.14 CCV00158.1 - 1e-18 66.9 0.1 2.2e-18 65.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal L28 family Brix PF04427.13 CCV00159.1 - 2.7e-47 160.9 0.1 3.5e-47 160.5 0.1 1.2 1 0 0 1 1 1 1 Brix domain ATP-sulfurylase PF01747.12 CCV00159.1 - 0.076 12.3 0.9 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 ATP-sulfurylase DAO PF01266.19 CCV00160.1 - 4.8e-46 157.2 0.2 7.8e-46 156.6 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCV00160.1 - 2.9e-09 36.2 4.3 0.00017 20.6 0.4 2.7 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.2 CCV00160.1 - 3.9e-07 29.5 2.1 4.6e-06 25.9 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCV00160.1 - 6.4e-05 22.9 0.6 0.00073 19.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCV00160.1 - 0.00012 21.0 0.4 0.0098 14.7 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 CCV00160.1 - 0.0031 17.1 0.2 0.0081 15.8 0.2 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 CCV00160.1 - 0.0032 17.4 0.3 0.024 14.6 0.4 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CCV00160.1 - 0.0075 15.3 0.6 0.029 13.4 0.4 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CCV00160.1 - 0.012 15.9 0.5 0.03 14.7 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCV00160.1 - 0.015 13.7 1.2 0.024 13.1 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein HCaRG PF07258.9 CCV00160.1 - 0.032 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 HCaRG protein Saccharop_dh PF03435.13 CCV00160.1 - 0.065 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pyr_redox_3 PF13738.1 CCV00160.1 - 0.068 13.2 0.1 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCV00160.1 - 0.11 11.6 0.8 0.26 10.3 0.1 2.0 2 0 0 2 2 2 0 Thi4 family HHH_4 PF14490.1 CCV00160.1 - 0.12 12.2 0.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain Rad17 PF03215.10 CCV00161.1 - 6.8e-33 114.1 0.0 1.8e-20 73.1 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CCV00161.1 - 5.8e-08 32.9 2.2 1.9e-07 31.2 1.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCV00161.1 - 7.4e-05 22.8 0.0 0.00019 21.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCV00161.1 - 0.00066 19.6 0.3 0.08 12.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 CCV00161.1 - 0.0017 18.6 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CCV00161.1 - 0.0074 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CCV00161.1 - 0.011 16.4 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCV00161.1 - 0.028 13.8 0.2 9.5 5.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCV00161.1 - 0.029 14.5 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CCV00161.1 - 0.047 12.7 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 CCV00161.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 CCV00161.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 CCV00161.1 - 0.19 11.4 4.1 0.1 12.3 0.3 2.5 2 1 0 2 2 2 0 Part of AAA domain IBN_N PF03810.14 CCV00162.1 - 9.1e-16 57.5 0.0 6.5e-15 54.8 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.5 CCV00162.1 - 8.3e-08 31.1 0.0 1.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.1 CCV00162.1 - 9.8e-05 22.5 4.9 0.057 13.6 0.1 3.9 2 1 0 3 3 3 2 HEAT repeats Xpo1 PF08389.7 CCV00162.1 - 0.0021 17.9 1.3 0.017 15.0 0.0 3.2 4 0 0 4 4 4 1 Exportin 1-like protein Vac14_Fab1_bd PF12755.2 CCV00162.1 - 0.025 14.9 0.1 1.3 9.4 0.0 3.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CCV00162.1 - 3.3 8.0 10.9 1.9 8.8 0.0 5.6 7 0 0 7 7 7 0 HEAT repeat Sdh5 PF03937.11 CCV00163.1 - 3.5e-25 87.5 0.6 4.9e-25 87.0 0.4 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Ribosomal_L37ae PF01780.14 CCV00164.1 - 5.1e-38 128.8 6.9 6.3e-38 128.5 4.8 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family DUF1364 PF07102.7 CCV00164.1 - 0.008 16.0 0.2 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) Zn_Tnp_IS1595 PF12760.2 CCV00164.1 - 0.013 15.2 1.9 0.022 14.5 1.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CCV00164.1 - 0.027 14.1 1.6 0.04 13.5 1.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.5 CCV00164.1 - 0.053 12.9 3.0 0.34 10.4 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.10 CCV00164.1 - 0.069 12.9 2.2 2.1 8.1 0.0 2.4 1 1 1 2 2 2 0 BED zinc finger C1_1 PF00130.17 CCV00164.1 - 0.075 12.7 1.8 0.12 12.1 1.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-FCS PF06467.9 CCV00164.1 - 0.089 12.4 1.5 0.43 10.2 0.1 2.1 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif NOB1_Zn_bind PF08772.6 CCV00164.1 - 0.1 12.4 3.3 0.73 9.7 0.2 2.8 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-C4_ClpX PF06689.8 CCV00164.1 - 0.1 12.1 0.2 0.1 12.1 0.2 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-ribbon_3 PF13248.1 CCV00164.1 - 0.15 11.3 1.0 5.4 6.3 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain C1_2 PF03107.11 CCV00164.1 - 0.35 11.0 2.5 5.5 7.2 0.3 2.3 2 0 0 2 2 2 0 C1 domain zf-Sec23_Sec24 PF04810.10 CCV00164.1 - 1.6 8.3 4.1 1.6 8.3 0.1 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.1 CCV00164.1 - 1.6 9.1 5.3 1.1 9.6 0.6 2.2 1 1 1 2 2 2 0 Zinc-finger double domain Prok-RING_2 PF14445.1 CCV00164.1 - 1.7 8.6 4.9 3.5 7.6 3.0 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 DnaJ PF00226.26 CCV00165.1 - 6.3e-07 29.0 0.0 7.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CCV00165.1 - 0.0017 18.1 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Pam16 WD40 PF00400.27 CCV00166.1 - 7.2e-17 60.5 15.6 2.5e-05 23.9 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 CCV00166.1 - 0.0096 14.1 4.0 0.63 8.1 0.1 2.9 2 2 1 4 4 4 2 Nucleoporin Nup120/160 Sec23_trunk PF04811.10 CCV00167.1 - 5.7e-74 248.5 0.0 7.9e-74 248.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCV00167.1 - 1.5e-35 120.7 0.3 2.7e-35 119.8 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCV00167.1 - 1.3e-30 105.7 0.1 2.4e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCV00167.1 - 3.4e-17 61.7 6.8 7.1e-17 60.6 4.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCV00167.1 - 4.1e-12 45.6 0.0 8.3e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat DUF3608 PF12257.3 CCV00168.1 - 2.1e-64 217.1 0.0 7.8e-64 215.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 CCV00168.1 - 7.9e-19 67.1 1.0 1.6e-18 66.2 0.2 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PAP2 PF01569.16 CCV00169.1 - 1.5e-11 44.0 8.7 1.5e-11 44.0 6.0 2.3 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 CCV00169.1 - 1.7e-05 24.4 9.9 1.7e-05 24.4 6.9 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 CCV00169.1 - 2.4 8.4 11.6 0.042 14.1 2.3 2.3 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Peptidase_S26 PF10502.4 CCV00170.1 - 6.7e-08 32.1 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 CCV00170.1 - 1.1e-05 25.0 0.0 3.2e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like Mito_carr PF00153.22 CCV00171.1 - 5.8e-36 122.0 0.4 3.4e-18 65.1 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein IF4E PF01652.13 CCV00172.1 - 5.1e-32 110.6 0.0 1.1e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Fer2_3 PF13085.1 CCV00173.1 - 2.5e-33 114.2 0.0 4e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CCV00173.1 - 7.5e-10 39.0 6.0 7.5e-10 39.0 4.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CCV00173.1 - 1.2e-09 38.0 4.9 1.2e-09 38.0 3.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CCV00173.1 - 6.7e-05 23.0 3.2 0.063 13.5 0.2 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CCV00173.1 - 0.00013 21.6 6.4 0.00024 20.8 3.0 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CCV00173.1 - 0.00023 21.5 3.0 0.00023 21.5 2.1 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 CCV00173.1 - 0.0014 18.2 0.4 0.0014 18.2 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 CCV00173.1 - 0.0041 17.4 5.0 0.0041 17.4 3.5 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 CCV00173.1 - 0.21 12.1 5.5 2 9.0 0.2 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_20 PF14691.1 CCV00173.1 - 0.31 10.6 3.4 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster BIR PF00653.16 CCV00175.1 - 2.6e-16 59.7 2.0 6.7e-16 58.4 1.4 1.7 1 1 0 1 1 1 1 Inhibitor of Apoptosis domain zf-BED PF02892.10 CCV00175.1 - 0.099 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 BED zinc finger Sec10 PF07393.6 CCV00176.1 - 2.7e-84 283.7 0.0 6.1e-84 282.5 0.0 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec10 F-box PF00646.28 CCV00176.1 - 0.00024 20.6 0.1 0.00024 20.6 0.1 3.0 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.2 CCV00176.1 - 0.057 13.1 0.4 0.057 13.1 0.3 2.7 3 0 0 3 3 3 0 F-box-like SBF PF01758.11 CCV00177.1 - 4.8e-47 159.7 13.8 4.8e-47 159.7 9.6 2.1 2 0 0 2 2 2 1 Sodium Bile acid symporter family Ras PF00071.17 CCV00178.1 - 7.3e-41 139.2 0.0 1e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCV00178.1 - 3e-18 66.4 0.0 5.3e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCV00178.1 - 1.7e-06 27.3 0.0 2.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 CCV00178.1 - 0.0007 19.7 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 CCV00178.1 - 0.0037 16.4 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Sigma54_activat PF00158.21 CCV00178.1 - 0.0043 16.5 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain MMR_HSR1 PF01926.18 CCV00178.1 - 0.0049 16.8 0.0 0.012 15.5 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 CCV00178.1 - 0.021 14.4 0.1 0.057 13.0 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 CCV00178.1 - 0.024 14.6 1.2 0.061 13.2 0.8 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 CCV00178.1 - 0.035 13.8 0.1 0.083 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CCV00178.1 - 0.041 13.3 0.0 0.32 10.4 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.24 CCV00178.1 - 0.041 14.0 0.0 0.098 12.8 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CCV00178.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CCV00178.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 RNA helicase SRPRB PF09439.5 CCV00178.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 CCV00178.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter WD40 PF00400.27 CCV00179.1 - 5.2e-42 140.2 14.1 1.7e-10 40.3 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat DUF4613 PF15390.1 CCV00179.1 - 0.027 12.6 0.0 0.039 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PQQ_3 PF13570.1 CCV00179.1 - 2.5 8.5 16.5 1 9.7 0.2 5.7 4 1 2 6 6 6 0 PQQ-like domain Rib_5-P_isom_A PF06026.9 CCV00180.1 - 7.4e-48 162.1 0.1 1.1e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 CCV00180.1 - 0.045 13.3 1.1 0.18 11.4 0.7 1.9 1 1 0 1 1 1 0 DeoR C terminal sensor domain Ribosomal_L18e PF00828.14 CCV00180.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L18e/L15 Rubi_NSP_C PF12601.3 CCV00180.1 - 0.15 11.9 1.0 13 5.7 0.2 2.7 1 1 1 2 2 2 0 Rubivirus non-structural protein DUF3321 PF11968.3 CCV00181.1 - 1.3e-56 191.6 0.0 1.7e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 CCV00181.1 - 3.3e-08 33.4 0.0 8.2e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CCV00181.1 - 3.5e-07 30.0 0.0 4.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CCV00181.1 - 0.00026 21.4 0.0 0.00061 20.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCV00181.1 - 0.029 14.8 0.1 0.066 13.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CCV00181.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CCV00181.1 - 0.28 11.2 1.9 0.93 9.5 0.5 2.4 2 1 0 2 2 2 0 Methyltransferase domain Glutaredoxin PF00462.19 CCV00182.1 - 3.8e-18 65.2 0.0 5.5e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 CCV00182.1 - 0.00038 20.6 0.2 0.0023 18.0 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.1 CCV00182.1 - 0.028 14.6 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 CCV00182.1 - 0.044 14.0 0.0 0.06 13.6 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 CCV00182.1 - 0.051 13.4 0.0 0.09 12.5 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.1 CCV00182.1 - 0.08 12.9 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like DUF953 PF06110.6 CCV00182.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DSBA PF01323.15 CCV00182.1 - 0.19 11.2 0.4 0.54 9.7 0.1 1.7 1 1 0 2 2 2 0 DSBA-like thioredoxin domain WD40 PF00400.27 CCV00183.1 - 1.7e-38 129.1 13.9 1.2e-06 28.1 0.0 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat EST1_DNA_bind PF10373.4 CCV00184.1 - 2.9e-28 98.8 0.0 6.3e-28 97.7 0.0 1.6 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 CCV00184.1 - 1.4e-11 44.5 0.0 3.9e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Telomerase activating protein Est1 RPN7 PF10602.4 CCV00185.1 - 1.7e-13 50.3 0.0 2.9e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_2 PF07719.12 CCV00185.1 - 0.005 16.6 3.6 0.0072 16.1 1.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCV00185.1 - 0.013 15.0 0.5 0.036 13.6 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCV00185.1 - 0.037 13.6 0.3 0.037 13.6 0.2 2.0 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.1 CCV00185.1 - 0.053 13.4 9.2 0.047 13.6 2.9 3.0 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCV00185.1 - 0.097 13.3 0.9 0.097 13.3 0.6 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCV00185.1 - 0.17 11.7 4.0 0.13 12.1 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RWD PF05773.17 CCV00186.1 - 2.6e-17 62.7 0.2 2.6e-17 62.7 0.2 1.6 2 0 0 2 2 2 1 RWD domain HSP70 PF00012.15 CCV00187.1 - 7.7e-253 839.8 13.0 8.9e-253 839.6 9.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCV00187.1 - 1.3e-15 56.8 4.4 1.2e-13 50.3 1.7 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CCV00187.1 - 0.0019 18.0 8.3 0.26 11.1 0.8 3.7 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.11 CCV00187.1 - 0.0028 17.2 0.0 0.0062 16.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Seryl_tRNA_N PF02403.17 CCV00187.1 - 0.24 11.4 8.3 0.67 9.9 5.8 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Hydantoinase_A PF01968.13 CCV00187.1 - 4 6.4 9.6 0.21 10.6 0.1 3.1 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase DUF3818 PF12825.2 CCV00188.1 - 1.2e-96 323.4 1.5 1.8e-96 322.8 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PX PF00787.19 CCV00188.1 - 1.4e-15 57.0 0.1 9.3e-15 54.4 0.0 2.3 2 0 0 2 2 2 1 PX domain PXB PF12828.2 CCV00188.1 - 1.2e-08 34.6 0.3 3.3e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 PX-associated MAS20 PF02064.10 CCV00189.1 - 2.6e-19 69.3 2.2 2.6e-19 69.3 1.6 2.7 2 2 0 2 2 2 1 MAS20 protein import receptor PMC2NT PF08066.7 CCV00189.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Mitofilin PF09731.4 CCV00189.1 - 0.17 10.5 20.0 0.32 9.6 10.2 2.3 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Zip PF02535.17 CCV00189.1 - 0.3 10.0 0.7 0.44 9.5 0.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter vMSA PF00695.14 CCV00189.1 - 0.36 9.9 2.1 0.61 9.2 1.5 1.4 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Choline_kinase PF01633.15 CCV00190.1 - 6.3e-34 117.4 0.0 1.8e-22 79.9 0.0 3.0 2 1 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.18 CCV00190.1 - 2.8e-08 33.8 0.0 0.0076 15.9 0.0 3.4 2 1 0 2 2 2 2 Phosphotransferase enzyme family XPG_I_2 PF12813.2 CCV00191.1 - 5.8e-07 29.2 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing CDC45 PF02724.9 CCV00191.1 - 0.0074 14.3 1.4 0.011 13.8 0.9 1.2 1 0 0 1 1 1 1 CDC45-like protein VID27 PF08553.5 CCV00191.1 - 0.074 11.2 6.8 0.1 10.8 4.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Daxx PF03344.10 CCV00191.1 - 0.5 8.7 8.6 0.7 8.3 6.0 1.1 1 0 0 1 1 1 0 Daxx Family RRP7 PF12923.2 CCV00191.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.0 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) Nop14 PF04147.7 CCV00191.1 - 1.5 6.6 12.0 2.3 6.0 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 CCV00191.1 - 2.8 6.8 5.8 4.7 6.1 4.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FHA PF00498.21 CCV00192.1 - 3.8e-16 58.9 0.0 5.6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 FHA domain RNA_lig_T4_1 PF09511.5 CCV00193.1 - 8e-73 244.5 0.0 1.5e-72 243.6 0.0 1.5 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.6 CCV00193.1 - 7.5e-12 45.4 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 CCV00193.1 - 0.035 14.9 0.0 0.12 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Ribonuclease PF00545.15 CCV00193.1 - 0.083 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 ribonuclease RNA_ligase PF09414.5 CCV00193.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 RNA ligase Cu-oxidase_3 PF07732.10 CCV00194.1 - 2.5e-32 111.0 5.1 3.8e-22 78.2 0.3 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 CCV00194.1 - 9.1e-28 97.1 0.0 4.2e-27 94.9 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CCV00194.1 - 1.2e-18 66.9 1.5 1.2e-18 66.9 1.0 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CCV00195.1 - 6.6e-31 106.6 5.6 6.6e-31 106.6 3.9 3.1 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 CCV00195.1 - 1.2e-30 106.4 0.0 6.3e-29 100.9 0.0 2.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 CCV00195.1 - 3.7e-19 68.5 4.0 4.5e-19 68.3 0.1 3.1 4 1 0 4 4 4 1 Multicopper oxidase Phosphoesterase PF04185.9 CCV00196.1 - 4.8e-73 246.5 2.1 6.3e-73 246.1 1.5 1.1 1 0 0 1 1 1 1 Phosphoesterase family Phosphoesterase PF04185.9 CCV00197.1 - 1.5e-78 264.6 4.3 2.2e-78 264.1 3.0 1.2 1 0 0 1 1 1 1 Phosphoesterase family NMT1 PF09084.6 CCV00198.1 - 1.8e-73 246.7 0.0 2.1e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 CCV00198.1 - 2.3e-06 27.2 0.3 4.3e-05 23.0 0.2 3.2 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.2 CCV00198.1 - 0.00036 20.0 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.2 CCV00198.1 - 0.012 14.5 0.1 0.17 10.8 0.0 2.1 2 0 0 2 2 2 0 PBP superfamily domain DUF1399 PF07173.7 CCV00199.1 - 5e-15 55.9 0.6 4.8e-14 52.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1399) Acetyltransf_2 PF00797.12 CCV00200.1 - 5.3e-26 91.6 0.0 6.4e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase Glyco_hydro_4 PF02056.11 CCV00200.1 - 0.055 12.7 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase Catalase PF00199.14 CCV00201.1 - 8.6e-162 538.1 0.1 1.1e-161 537.8 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CCV00201.1 - 8.5e-24 83.2 0.0 1.8e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 CCV00201.1 - 0.00054 19.4 0.0 0.00098 18.6 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Transp_cyt_pur PF02133.10 CCV00202.1 - 6.4e-34 117.2 26.1 9.7e-34 116.6 18.1 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidohydro_3 PF07969.6 CCV00202.1 - 1.3e-31 110.2 0.2 5.6e-31 108.1 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CCV00202.1 - 5.2e-12 46.3 3.0 5.2e-12 46.3 2.1 1.8 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 CCV00202.1 - 0.015 15.0 0.1 0.059 13.1 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase TauD PF02668.11 CCV00203.1 - 6.3e-53 180.0 0.7 7.9e-53 179.7 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 CCV00203.1 - 0.041 14.4 0.1 16 6.0 0.0 2.6 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 CCV00204.1 - 8.4e-118 393.6 40.0 1e-117 393.4 27.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Allantoicase PF03561.10 CCV00205.1 - 2.2e-43 147.3 0.0 2.6e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Allantoicase repeat Polysacc_deac_1 PF01522.16 CCV00206.1 - 1.2e-14 54.0 0.0 2.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Cu-oxidase_2 PF07731.9 CCV00207.1 - 1.7e-38 131.2 9.8 2.3e-38 130.7 0.7 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 CCV00207.1 - 1.2e-35 122.7 0.1 6.5e-35 120.3 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 CCV00207.1 - 2.9e-26 91.5 9.1 8.6e-24 83.5 0.3 4.9 4 1 1 5 5 5 2 Multicopper oxidase Cupredoxin_1 PF13473.1 CCV00207.1 - 0.00012 21.8 0.0 5.2 7.0 0.0 3.7 3 0 0 3 3 3 3 Cupredoxin-like domain Polysacc_deac_1 PF01522.16 CCV00208.1 - 3.9e-28 97.5 0.0 7.8e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Apt1 PF10351.4 CCV00208.1 - 6 5.5 12.2 9.4 4.9 8.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Polysacc_deac_1 PF01522.16 CCV00209.1 - 6.8e-19 67.7 0.0 1.3e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase tRNA_int_endo_N PF02778.9 CCV00211.1 - 1.7e-07 30.6 0.0 3.1e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Kei1 PF08552.6 CCV00212.1 - 4.1e-43 147.2 1.4 7.3e-43 146.4 1.0 1.4 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 dsDNA_bind PF01984.15 CCV00212.1 - 2.2e-26 91.9 5.6 4.4e-26 90.9 3.8 1.5 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Ran_BP1 PF00638.13 CCV00213.1 - 1.2e-08 34.9 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain BCMA-Tall_bind PF09257.5 CCV00213.1 - 0.063 13.2 0.2 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 BCMA, TALL-1 binding W2 PF02020.13 CCV00214.1 - 1.5e-11 44.0 0.2 4.1e-11 42.6 0.1 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 CCV00214.1 - 3.3e-11 42.1 7.4 4.7e-06 25.8 0.3 3.6 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CCV00214.1 - 3.4e-06 26.5 3.6 0.0063 16.0 0.0 2.8 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 CCV00214.1 - 0.00081 18.7 0.0 0.0018 17.6 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CCV00214.1 - 0.0098 15.9 0.0 0.044 13.8 0.0 2.1 2 0 0 2 2 2 1 MobA-like NTP transferase domain Flavoprotein PF02441.14 CCV00215.1 - 9.7e-32 109.3 0.3 1.3e-31 108.9 0.2 1.1 1 0 0 1 1 1 1 Flavoprotein Aldo_ket_red PF00248.16 CCV00216.1 - 7.2e-31 107.0 0.0 1.1e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Multi_ubiq PF14452.1 CCV00216.1 - 0.14 12.1 0.0 12 5.9 0.0 3.3 3 1 0 3 3 3 0 Multiubiquitin PGK PF00162.14 CCV00217.1 - 4e-152 506.2 1.5 4.5e-152 506.0 1.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase A_deaminase PF00962.17 CCV00218.1 - 1.9e-108 362.2 0.0 2.6e-108 361.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DASH_Spc34 PF08657.5 CCV00219.1 - 1.3e-11 44.7 1.7 3.7e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 DASH complex subunit Spc34 DUF3138 PF11336.3 CCV00219.1 - 0.19 9.8 0.7 0.32 9.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PfkB PF00294.19 CCV00220.1 - 8.5e-10 38.2 1.5 5.4e-07 29.0 0.0 3.0 3 0 0 3 3 3 3 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CCV00220.1 - 2.2e-09 36.8 0.0 4e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase DNA_pol_B PF00136.16 CCV00221.1 - 8e-108 361.1 0.0 1.9e-107 359.9 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 CCV00221.1 - 8.2e-49 165.5 0.1 1.4e-48 164.7 0.1 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.3 CCV00221.1 - 2e-22 78.7 1.4 6.5e-22 77.1 1.0 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_exo1 PF03104.14 CCV00221.1 - 9.8e-16 57.5 0.0 1.7e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Ribosomal_L35Ae PF01247.13 CCV00222.1 - 6.1e-40 134.8 0.3 7.4e-40 134.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CCV00222.1 - 0.018 14.9 0.0 2.5 8.0 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain zf-C2H2_jaz PF12171.3 CCV00223.1 - 7.6e-09 35.4 1.2 1.5e-08 34.5 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCV00223.1 - 0.00044 20.3 0.7 0.00076 19.6 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCV00223.1 - 0.011 15.8 0.4 0.018 15.1 0.2 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CCV00223.1 - 0.023 15.0 1.2 0.052 13.9 0.8 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCV00223.1 - 0.047 14.0 1.0 0.14 12.5 0.7 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger DAO PF01266.19 CCV00224.1 - 4e-15 55.5 0.1 5.7e-07 28.7 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCV00224.1 - 3.2e-05 22.9 0.0 4.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CCV00224.1 - 0.0003 20.7 0.1 0.00088 19.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCV00224.1 - 0.0031 17.8 0.1 0.015 15.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCV00224.1 - 0.0053 16.6 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 CCV00224.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 CCV00224.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 CCV00224.1 - 0.072 12.1 0.0 0.22 10.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 CCV00224.1 - 0.12 12.4 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1014 PF06244.7 CCV00225.1 - 5.7e-25 87.9 6.4 1.1e-24 86.9 3.4 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) U79_P34 PF03064.11 CCV00225.1 - 3.5 7.0 21.0 0.41 10.1 10.4 1.9 1 1 1 2 2 2 0 HSV U79 / HCMV P34 BNIP2 PF12496.3 CCV00225.1 - 7.1 6.8 6.9 3.8 7.7 0.0 2.5 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF3835 PF12927.2 CCV00226.1 - 1.2e-05 26.1 0.1 1.2e-05 26.1 0.0 3.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3835) DUF3138 PF11336.3 CCV00226.1 - 0.5 8.4 1.6 0.79 7.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_L27 PF01016.14 CCV00227.1 - 2.5e-31 107.2 0.7 7e-31 105.8 0.6 1.6 2 0 0 2 2 2 1 Ribosomal L27 protein eRF1_1 PF03463.10 CCV00227.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 eRF1 domain 1 Tim17 PF02466.14 CCV00228.1 - 6.3e-26 90.9 3.9 7.8e-26 90.6 2.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF1712 PF08217.6 CCV00230.1 - 0.0038 15.5 0.0 0.005 15.1 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) PDH PF02153.12 CCV00232.1 - 4.3e-14 52.0 0.0 7.3e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 CCV00232.1 - 1e-06 28.7 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CCV00232.1 - 1.2e-06 28.8 0.1 6e-06 26.6 0.0 2.3 3 1 0 3 3 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.4 CCV00232.1 - 6.8e-05 22.5 0.4 0.00014 21.5 0.2 1.5 1 0 0 1 1 1 1 Rossmann-like domain ApbA PF02558.11 CCV00232.1 - 0.00024 20.5 0.1 0.001 18.5 0.0 1.8 1 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 CCV00232.1 - 0.00042 19.5 0.0 0.00083 18.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CCV00232.1 - 0.007 16.4 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 CCV00232.1 - 0.014 14.7 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 CCV00232.1 - 0.017 14.7 0.2 0.35 10.5 0.0 2.2 1 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 CCV00232.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.17 CCV00232.1 - 0.062 13.8 0.2 0.32 11.5 0.1 2.4 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ThiF PF00899.16 CCV00232.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 ThiF family Alg14 PF08660.6 CCV00233.1 - 6.1e-46 156.5 0.0 7.9e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_transf_28 PF03033.15 CCV00233.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain SNARE PF05739.14 CCV00234.1 - 1.5e-12 46.9 7.8 1.5e-12 46.9 5.4 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CCV00234.1 - 1.6e-09 37.8 0.3 1.6e-09 37.8 0.2 2.4 2 0 0 2 2 2 1 Syntaxin PBP1_TM PF14812.1 CCV00234.1 - 0.00041 20.6 0.1 0.00091 19.4 0.1 1.5 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3611 PF12263.3 CCV00234.1 - 0.0028 17.0 0.3 0.0042 16.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) DUF4658 PF15555.1 CCV00234.1 - 0.004 17.0 0.6 3.2 7.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4658) Prominin PF05478.6 CCV00234.1 - 0.03 11.8 2.5 0.13 9.7 0.1 2.2 2 0 0 2 2 2 0 Prominin Allexi_40kDa PF05549.6 CCV00234.1 - 0.033 13.4 3.8 0.055 12.7 0.1 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF2077 PF09850.4 CCV00234.1 - 0.041 13.2 0.4 0.041 13.2 0.3 2.2 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) Herpes_gE PF02480.11 CCV00234.1 - 0.044 12.0 0.1 0.071 11.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Nsp1_C PF05064.8 CCV00234.1 - 0.067 12.8 0.0 0.067 12.8 0.0 2.8 2 1 0 3 3 3 0 Nsp1-like C-terminal region SbcCD_C PF13558.1 CCV00234.1 - 0.078 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF3708 PF12501.3 CCV00234.1 - 0.13 12.1 7.1 0.26 11.1 0.4 2.7 2 1 1 3 3 3 0 Phosphate ATP-binding cassette transporter Use1 PF09753.4 CCV00234.1 - 0.13 11.6 6.4 0.22 10.9 4.5 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 Laminin_II PF06009.7 CCV00234.1 - 0.14 11.8 5.3 1 9.0 1.3 2.4 2 0 0 2 2 2 0 Laminin Domain II Synaptobrevin PF00957.16 CCV00234.1 - 0.18 11.4 7.4 0.035 13.6 2.1 2.0 2 0 0 2 2 2 0 Synaptobrevin Baculo_PEP_C PF04513.7 CCV00234.1 - 0.33 10.7 8.3 0.46 10.3 0.4 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF745 PF05335.8 CCV00234.1 - 1 8.8 10.3 0.25 10.8 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) V-SNARE PF05008.10 CCV00234.1 - 1.6 8.9 15.5 0.79 9.9 1.2 4.1 4 1 1 5 5 4 0 Vesicle transport v-SNARE protein N-terminus Shisa PF13908.1 CCV00234.1 - 4.7 7.3 5.8 2.8 8.0 0.1 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Ribosomal_L20 PF00453.13 CCV00234.1 - 4.8 7.1 7.4 10 6.0 0.8 2.6 2 1 0 2 2 2 0 Ribosomal protein L20 Ribosomal_L18e PF00828.14 CCV00235.1 - 1.5e-24 86.8 0.0 3.3e-24 85.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 MerR_1 PF13411.1 CCV00235.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 MerR HTH family regulatory protein DEAD PF00270.24 CCV00236.1 - 5.6e-42 143.0 0.1 3e-41 140.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCV00236.1 - 6.1e-25 86.9 0.0 1.3e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCV00236.1 - 1.9e-05 23.6 0.0 2.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CCV00236.1 - 0.0038 17.0 0.0 0.017 14.9 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ACC_central PF08326.7 CCV00237.1 - 1.1e-160 536.2 0.0 1.3e-160 535.9 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 CCV00237.1 - 2.5e-151 504.3 0.0 3.4e-151 503.9 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CCV00237.1 - 2.5e-49 167.4 0.0 4.7e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CCV00237.1 - 8.2e-23 80.6 0.0 2.6e-22 78.9 0.0 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCV00237.1 - 1.2e-18 67.0 0.0 1.2e-17 63.7 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CCV00237.1 - 3.1e-13 49.8 0.0 8.5e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CCV00237.1 - 2.4e-11 43.1 0.0 5e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CCV00237.1 - 5.8e-05 22.6 0.0 0.00021 20.8 0.0 1.9 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.17 CCV00237.1 - 0.0027 17.0 0.0 0.0069 15.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCV00237.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus RnfC_N PF13375.1 CCV00237.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Cytochrom_C1 PF02167.10 CCV00238.1 - 2e-84 282.6 0.0 2.6e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CCV00238.1 - 0.0029 17.7 0.0 0.0071 16.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Ribosomal_S19 PF00203.16 CCV00239.1 - 8.5e-31 105.4 0.4 1.4e-30 104.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 ERCC4 PF02732.10 CCV00239.1 - 6.9e-23 80.9 0.0 1.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 CCV00239.1 - 0.0024 18.0 0.6 0.0056 16.8 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain FliH PF02108.11 CCV00239.1 - 0.016 15.1 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Flagellar assembly protein FliH Ribosomal_60s PF00428.14 CCV00240.1 - 9.4e-28 96.4 13.1 1.1e-27 96.2 9.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Rnk_N PF14760.1 CCV00240.1 - 0.1 12.6 0.9 0.23 11.5 0.1 1.9 2 0 0 2 2 2 0 Rnk N-terminus RhoGAP PF00620.22 CCV00241.1 - 2.3e-49 166.9 0.6 6.9e-49 165.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 CCV00241.1 - 2.7e-09 37.0 2.0 5.3e-09 36.1 0.3 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain CAP59_mtransfer PF11735.3 CCV00242.1 - 1.5e-66 224.1 0.0 1.3e-65 221.0 0.0 2.0 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 Mg_trans_NIPA PF05653.9 CCV00243.1 - 3e-76 256.2 15.2 3.8e-76 255.9 10.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 CCV00243.1 - 2.2e-07 31.0 1.7 2.2e-07 31.0 1.2 2.9 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 CCV00243.1 - 0.00013 22.0 4.3 0.00013 22.0 3.0 2.6 2 1 0 2 2 2 1 EamA-like transporter family PPP4R2 PF09184.6 CCV00244.1 - 1e-10 41.6 0.0 1.4e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 PPP4R2 SSF PF00474.12 CCV00245.1 - 3.8e-08 32.3 18.6 4.8e-07 28.7 12.9 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family Cytochrom_B_N PF00033.14 CCV00245.1 - 2.2 7.5 17.3 0.016 14.5 4.6 2.8 2 2 1 3 3 3 0 Cytochrome b(N-terminal)/b6/petB Spore_permease PF03845.8 CCV00245.1 - 5.1 5.6 22.7 0.009 14.7 6.6 2.1 2 0 0 2 2 2 0 Spore germination protein Ada3 PF10198.4 CCV00246.1 - 6.7e-22 77.6 0.4 1.3e-21 76.7 0.3 1.4 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 ELO PF01151.13 CCV00247.1 - 6.2e-99 330.3 46.5 4.3e-55 186.7 14.0 2.0 2 0 0 2 2 2 2 GNS1/SUR4 family UQ_con PF00179.21 CCV00248.1 - 4.6e-32 110.3 0.2 5.7e-31 106.8 0.2 2.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCV00248.1 - 0.0011 18.8 0.1 0.0013 18.6 0.1 1.3 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 CCV00248.1 - 0.0037 17.0 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Myb_DNA-binding PF00249.26 CCV00249.1 - 2.5e-09 37.0 0.0 4.9e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCV00249.1 - 3.3e-05 23.9 0.4 0.13 12.3 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain HeLo PF14479.1 CCV00249.1 - 6.6 6.4 9.4 0.38 10.4 1.6 2.3 2 1 0 2 2 2 0 Prion-inhibition and propagation Oxidored_FMN PF00724.15 CCV00250.1 - 3.2e-49 167.7 0.0 1.4e-43 149.2 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family ORC5_C PF14630.1 CCV00251.1 - 2.8e-50 171.3 0.0 3.5e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus RRM_5 PF13893.1 CCV00252.1 - 0.008 16.0 0.1 0.018 14.8 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCV00252.1 - 0.011 15.3 0.1 0.042 13.4 0.1 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dyp_perox PF04261.7 CCV00252.1 - 0.046 12.4 0.1 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 Dyp-type peroxidase family 2-Hacid_dh PF00389.25 CCV00253.1 - 3.7e-22 78.2 0.0 3.7e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.14 CCV00253.1 - 1.1e-09 37.7 0.0 2.5e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M16 PF00675.15 CCV00254.1 - 1.8e-20 73.1 0.1 3.4e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCV00254.1 - 1.3e-16 60.8 0.0 4.5e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Kin17_mid PF10357.4 CCV00255.1 - 9.2e-45 151.3 0.0 1.5e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein PAT1 PF09770.4 CCV00255.1 - 0.034 12.3 3.5 0.039 12.1 2.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SHMT PF00464.14 CCV00256.1 - 7.7e-172 571.1 0.0 8.9e-172 570.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CCV00256.1 - 1.7e-08 34.0 0.0 5.3e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CCV00256.1 - 0.0018 17.3 0.0 0.0043 16.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Macro PF01661.16 CCV00256.1 - 0.022 14.6 0.1 0.07 13.0 0.0 1.8 2 0 0 2 2 2 0 Macro domain Aminotran_5 PF00266.14 CCV00256.1 - 0.091 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Asp_protease PF09668.5 CCV00257.1 - 1e-58 196.2 0.0 1.9e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 CCV00257.1 - 5.8e-11 42.7 0.0 1.1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 CCV00257.1 - 3.4e-10 39.1 0.0 7.2e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 CCV00257.1 - 8e-07 28.7 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CCV00257.1 - 3.5e-06 26.9 0.0 7.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CCV00257.1 - 6.7e-06 25.9 0.0 2.2e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 CCV00257.1 - 0.0003 20.4 0.1 0.0011 18.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 CCV00257.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain OB_NTP_bind PF07717.11 CCV00258.1 - 7.9e-24 83.6 0.0 2.3e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CCV00258.1 - 3.4e-17 62.3 0.0 2.2e-16 59.7 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCV00258.1 - 1.4e-12 47.3 0.0 3.1e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCV00258.1 - 0.00041 20.5 0.4 0.003 17.7 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCV00258.1 - 0.00053 19.8 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCV00258.1 - 0.0018 17.2 0.0 0.0043 15.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 CCV00258.1 - 0.003 17.8 0.0 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 ABC transporter DEAD PF00270.24 CCV00258.1 - 0.0041 16.6 0.5 1.8 8.0 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.1 CCV00258.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 CCV00258.1 - 0.016 14.2 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 CCV00258.1 - 0.021 14.1 0.0 0.056 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CCV00258.1 - 0.024 14.9 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCV00258.1 - 0.038 14.3 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CCV00258.1 - 0.048 13.5 0.1 9.2 6.0 0.0 2.3 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCV00258.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 CCV00258.1 - 0.054 13.1 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 CCV00258.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 CCV00258.1 - 0.081 12.1 0.0 0.22 10.7 0.0 1.7 2 0 0 2 2 1 0 PhoH-like protein AAA_29 PF13555.1 CCV00258.1 - 0.089 12.3 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 CCV00258.1 - 0.1 12.0 0.0 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 CCV00258.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 KaiC Miro PF08477.8 CCV00258.1 - 0.14 12.6 0.1 0.63 10.5 0.0 2.2 2 0 0 2 2 1 0 Miro-like protein G-alpha PF00503.15 CCV00258.1 - 0.16 10.5 0.1 0.33 9.5 0.0 1.5 2 0 0 2 2 2 0 G-protein alpha subunit Myosin_head PF00063.16 CCV00258.1 - 0.22 9.4 0.0 0.34 8.8 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) HECT PF00632.20 CCV00259.1 - 1e-76 258.1 0.0 1.4e-76 257.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CLASP_N PF12348.3 CCV00260.1 - 5.1e-56 189.5 0.3 1.2e-53 181.7 0.0 3.2 4 0 0 4 4 4 1 CLASP N terminal HEAT PF02985.17 CCV00260.1 - 3.6e-09 35.9 5.1 0.075 13.1 0.0 7.0 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 CCV00260.1 - 5e-05 23.5 16.0 0.27 11.5 0.8 5.4 5 0 0 5 5 5 3 HEAT repeats Cohesin_HEAT PF12765.2 CCV00260.1 - 0.016 15.1 0.2 13 5.8 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 CCV00260.1 - 0.18 11.6 0.1 9.8 5.9 0.0 2.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Rep_fac_C PF08542.6 CCV00261.1 - 9.8e-13 47.9 0.0 7.6e-12 45.0 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DEAD PF00270.24 CCV00261.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.24 CCV00261.1 - 0.021 15.0 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Met_asp_mut_E PF06368.6 CCV00261.1 - 0.039 12.1 0.1 0.053 11.7 0.1 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) PX PF00787.19 CCV00262.1 - 9.7e-20 70.4 0.1 2.1e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CCV00262.1 - 0.00022 20.5 4.2 0.049 12.8 0.4 2.2 2 0 0 2 2 2 2 Vps5 C terminal like FAM92 PF06730.6 CCV00262.1 - 0.029 13.6 0.1 0.058 12.7 0.1 1.4 1 0 0 1 1 1 0 FAM92 protein IncA PF04156.9 CCV00262.1 - 1 8.9 3.7 12 5.3 0.1 2.2 2 0 0 2 2 2 0 IncA protein ubiquitin PF00240.18 CCV00263.1 - 7e-33 111.8 0.7 1.1e-32 111.2 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCV00263.1 - 7.3e-18 64.0 0.3 1.1e-17 63.4 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.11 CCV00263.1 - 3.7e-09 36.3 6.5 9.4e-09 35.0 4.5 1.7 1 1 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.1 CCV00263.1 - 4.8e-05 23.5 0.2 0.00019 21.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCV00263.1 - 0.0014 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCV00263.1 - 0.0095 15.8 0.0 0.024 14.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-CSL PF05207.8 CCV00263.1 - 0.051 13.0 0.2 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 CSL zinc finger DUF2407 PF10302.4 CCV00263.1 - 0.054 13.6 0.0 0.064 13.4 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CCV00263.1 - 0.094 12.7 0.1 0.4 10.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) Aminotran_1_2 PF00155.16 CCV00264.1 - 3.3e-69 233.5 0.0 3.8e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SMC_Nse1 PF07574.8 CCV00265.1 - 7.5e-21 74.6 0.0 3.5e-19 69.2 0.0 2.0 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 CCV00265.1 - 0.00037 20.4 11.1 0.0007 19.5 7.7 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 CCV00265.1 - 0.0093 15.7 7.7 0.018 14.8 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H_2 PF13832.1 CCV00265.1 - 0.99 9.4 7.5 2.3 8.2 5.2 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_3 PF13920.1 CCV00265.1 - 1.1 8.9 6.4 2.2 8.0 4.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 CCV00265.1 - 1.5 9.0 8.0 4.4 7.5 5.6 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_2 PF13923.1 CCV00265.1 - 7.8 6.6 6.8 75 3.4 4.7 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MTHFR PF02219.12 CCV00266.1 - 4.5e-105 350.8 0.0 6.3e-105 350.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Actin PF00022.14 CCV00267.1 - 6.3e-20 70.9 0.0 3.1e-09 35.7 0.0 3.0 3 0 0 3 3 3 3 Actin MreB_Mbl PF06723.8 CCV00267.1 - 0.003 16.2 0.0 0.77 8.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein SAP PF02037.22 CCV00268.1 - 2.4e-11 42.8 0.8 4.6e-11 41.9 0.6 1.5 1 0 0 1 1 1 1 SAP domain IGPD PF00475.13 CCV00269.1 - 1.3e-55 187.2 0.5 1.7e-55 186.8 0.3 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase APC10 PF03256.11 CCV00269.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) WD40 PF00400.27 CCV00270.1 - 8.5e-11 41.3 8.5 0.08 12.8 0.0 6.4 7 1 0 7 7 7 4 WD domain, G-beta repeat Dynein_IC2 PF11540.3 CCV00270.1 - 0.037 13.4 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 SAC3_GANP PF03399.11 CCV00271.1 - 7.3e-61 205.2 0.3 9.3e-61 204.9 0.2 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CCV00271.1 - 0.00056 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 GHMP_kinases_N PF00288.21 CCV00272.1 - 7.1e-14 51.6 0.1 1.7e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain Nuf2 PF03800.9 CCV00273.1 - 4.4e-39 133.7 0.5 1.1e-38 132.5 0.4 1.6 1 0 0 1 1 1 1 Nuf2 family Apc13p PF05839.6 CCV00273.1 - 0.014 15.3 3.5 0.032 14.2 0.1 3.0 2 1 0 2 2 2 0 Apc13p protein DotA PF11388.3 CCV00273.1 - 0.075 13.0 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Phagosome trafficking protein DotA Reo_sigmaC PF04582.7 CCV00273.1 - 0.51 9.4 12.0 1.4 7.9 1.3 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Spc7 PF08317.6 CCV00273.1 - 1.6 7.2 31.5 0.046 12.3 8.7 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein Bacillus_HBL PF05791.6 CCV00273.1 - 1.9 7.8 10.9 0.23 10.8 0.4 3.3 2 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.7 CCV00273.1 - 6.1 6.6 14.3 2.3 8.0 3.0 3.3 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.6 CCV00273.1 - 8.3 6.8 18.0 1.3 9.4 1.9 4.0 2 2 2 4 4 4 0 Syntaxin 6, N-terminal AAA_13 PF13166.1 CCV00273.1 - 8.9 4.6 21.5 1.5 7.2 5.6 2.1 1 1 1 2 2 2 0 AAA domain Glutaredoxin PF00462.19 CCV00274.1 - 1.2e-17 63.6 0.0 6.2e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 CCV00274.1 - 7.6e-12 44.8 0.0 1.2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CCV00274.1 - 2.2e-05 24.5 0.0 0.02 15.0 0.0 3.0 2 1 1 3 3 3 2 Thioredoxin-like GST_N_3 PF13417.1 CCV00274.1 - 0.0031 17.6 0.0 0.0058 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain ArsC PF03960.10 CCV00274.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 ArsC family TrbC_Ftype PF09673.5 CCV00274.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Phosducin PF02114.11 CCV00274.1 - 0.15 10.7 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 Phosducin UCH PF00443.24 CCV00275.1 - 4.2e-76 255.5 0.0 5.7e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCV00275.1 - 1.9e-20 73.5 0.0 6.1e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CCV00275.1 - 3.4e-06 27.3 0.0 8.3e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 DUSP domain Zn-ribbon_8 PF09723.5 CCV00275.1 - 0.022 14.7 1.6 0.25 11.3 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 CCV00275.1 - 0.11 12.2 1.4 8.9 6.1 0.0 2.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DUF2420 PF10336.4 CCV00276.1 - 1.2e-18 66.7 0.0 2.1e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Pentapeptide_4 PF13599.1 CCV00276.1 - 0.094 12.5 2.1 2.7 7.8 1.4 2.4 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Abhydrolase_6 PF12697.2 CCV00278.1 - 4.3e-18 66.0 0.4 5.6e-18 65.6 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCV00278.1 - 1.9e-16 60.1 0.0 3.2e-16 59.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCV00278.1 - 8.5e-13 47.9 0.1 5.9e-12 45.2 0.0 2.2 3 0 0 3 3 3 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CCV00278.1 - 5.3e-06 25.8 0.1 4.2e-05 22.8 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CCV00278.1 - 2.8e-05 23.7 0.1 0.12 11.8 0.1 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 CCV00278.1 - 3.5e-05 23.3 0.0 0.00043 19.7 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 CCV00278.1 - 0.00012 21.7 0.0 0.0015 18.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 CCV00278.1 - 0.014 14.6 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.2 CCV00278.1 - 0.016 14.1 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Thioesterase PF00975.15 CCV00278.1 - 0.042 14.0 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF900 PF05990.7 CCV00278.1 - 0.12 11.6 0.0 4.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 CCV00278.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Histone PF00125.19 CCV00279.1 - 4.2e-30 103.6 0.7 6.4e-30 103.0 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCV00279.1 - 3.5e-05 23.8 0.0 5.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCV00279.1 - 0.0014 18.6 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCV00279.1 - 0.018 14.7 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 CCV00280.1 - 2.5e-13 49.9 0.1 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCV00280.1 - 0.00014 21.9 0.0 0.00019 21.5 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CCV00280.1 - 0.00033 20.5 0.1 0.00047 20.0 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CCV00280.1 - 0.00039 20.4 0.1 0.00079 19.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CCV00280.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Thiolase_N PF00108.18 CCV00281.1 - 1.2e-83 280.1 3.6 1.2e-83 280.1 2.5 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCV00281.1 - 5.9e-43 145.2 2.2 6.8e-43 145.0 0.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 CCV00281.1 - 0.052 13.5 0.7 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 CCV00281.1 - 0.07 12.5 0.3 0.07 12.5 0.2 3.5 4 0 0 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain Cyclin PF08613.6 CCV00282.1 - 1e-34 120.0 5.7 1.1e-21 77.8 0.2 2.5 3 0 0 3 3 3 2 Cyclin LIP PF03583.9 CCV00283.1 - 2.5e-51 174.5 0.0 3.4e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase ArgJ PF01960.13 CCV00284.1 - 1.4e-118 395.6 0.0 1.6e-118 395.4 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Zip PF02535.17 CCV00285.1 - 1e-54 185.7 6.6 1.2e-54 185.5 4.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3040 PF11239.3 CCV00285.1 - 0.029 14.4 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) CwfJ_C_1 PF04677.10 CCV00286.1 - 1.4e-14 53.8 0.0 2.2e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Pheromone PF08015.6 CCV00286.1 - 1.5 9.6 8.3 0.81 10.5 0.5 3.5 3 1 0 3 3 3 0 Fungal mating-type pheromone CwfJ_C_2 PF04676.9 CCV00287.1 - 9.5e-18 64.5 0.0 1.4e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 CCV00287.1 - 7.3e-06 25.6 0.1 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Innate_immun PF12782.2 CCV00287.1 - 0.021 14.0 0.2 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Ribosomal_S4e PF00900.15 CCV00288.1 - 1.9e-31 107.5 0.4 4e-31 106.5 0.3 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 CCV00288.1 - 1.4e-17 63.2 4.2 1.4e-17 63.2 2.9 1.9 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 CCV00288.1 - 0.0003 20.1 0.7 0.00055 19.3 0.0 1.9 2 0 0 2 2 2 1 S4 domain KOW PF00467.24 CCV00288.1 - 0.0017 17.9 1.0 0.0017 17.9 0.7 2.5 2 0 0 2 2 2 1 KOW motif DnaJ-X PF14308.1 CCV00289.1 - 9.1e-56 188.3 0.2 9.1e-56 188.3 0.2 1.8 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CCV00289.1 - 3.4e-18 65.1 0.3 3.4e-18 65.1 0.2 2.6 3 0 0 3 3 3 1 DnaJ domain DUF3337 PF11816.3 CCV00289.1 - 0.055 12.8 0.3 0.093 12.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) TFIIIC_delta PF12657.2 CCV00290.1 - 1.8e-18 66.8 1.1 4.6e-16 59.0 0.0 2.7 1 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 CCV00290.1 - 4.5e-12 45.7 2.3 9.2e-12 44.7 1.6 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex PHF5 PF03660.9 CCV00290.1 - 0.92 9.5 3.3 2.2 8.3 2.3 1.7 1 0 0 1 1 1 0 PHF5-like protein TPT PF03151.11 CCV00291.1 - 4e-30 104.4 8.9 4e-30 104.4 6.2 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CCV00291.1 - 1e-16 60.7 13.8 1.4e-16 60.3 9.6 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CCV00291.1 - 3e-16 59.6 20.5 1.4e-09 38.0 4.4 2.5 2 0 0 2 2 2 2 EamA-like transporter family BAG PF02179.11 CCV00291.1 - 2.9e-12 46.4 0.2 6.9e-12 45.3 0.2 1.6 1 0 0 1 1 1 1 BAG domain Nuc_sug_transp PF04142.10 CCV00291.1 - 2.5e-06 26.8 8.6 0.00092 18.3 0.2 2.5 2 1 0 2 2 2 2 Nucleotide-sugar transporter ubiquitin PF00240.18 CCV00291.1 - 0.00016 20.9 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family EmrE PF13536.1 CCV00291.1 - 0.0084 16.2 22.7 0.0088 16.2 4.0 2.9 2 1 0 2 2 2 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 CCV00291.1 - 0.17 11.7 7.0 3.9 7.3 0.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Multi_Drug_Res PF00893.14 CCV00291.1 - 2.1 8.8 8.0 0.33 11.4 1.7 2.3 2 0 0 2 2 2 0 Small Multidrug Resistance protein DEAD PF00270.24 CCV00293.1 - 7.1e-44 149.2 0.0 1.3e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CCV00293.1 - 1e-23 82.6 0.2 2e-23 81.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CCV00293.1 - 8e-20 70.4 0.0 1.6e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCV00293.1 - 0.0095 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CCV00293.1 - 0.047 13.6 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_22 PF13401.1 CCV00293.1 - 1.4 9.0 4.3 0.86 9.7 0.5 2.5 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.22 CCV00294.1 - 3.7e-28 97.0 1.9 1.7e-15 56.5 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein MatE PF01554.13 CCV00295.1 - 1.2e-42 145.2 32.5 4.9e-24 84.7 8.9 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 CCV00295.1 - 3.2e-08 33.5 19.7 5.1e-06 26.3 5.7 3.6 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DnaJ PF00226.26 CCV00297.1 - 6.1e-21 73.9 3.3 8e-21 73.5 0.9 2.4 2 0 0 2 2 2 1 DnaJ domain Aha1_N PF09229.6 CCV00299.1 - 1.6e-28 99.2 0.0 2.1e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 CCV00299.1 - 3e-17 62.8 0.0 1.1e-16 61.1 0.0 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 CCV00299.1 - 0.0025 17.9 0.0 0.0086 16.2 0.0 1.9 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport PCI PF01399.22 CCV00300.1 - 1.4e-09 38.1 2.6 1.6e-09 38.0 0.4 2.1 2 0 0 2 2 2 1 PCI domain SRPRB PF09439.5 CCV00300.1 - 0.022 13.9 1.0 0.041 13.0 0.7 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Methyltransf_27 PF13708.1 CCV00300.1 - 0.034 13.6 0.0 0.66 9.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain TPR_6 PF13174.1 CCV00300.1 - 0.22 12.0 3.4 4.1 8.0 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCV00300.1 - 0.34 11.6 12.2 3.3 8.5 0.1 4.7 4 3 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 CCV00301.1 - 1.4e-47 161.4 1.3 1.9e-47 160.9 0.9 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CCV00301.1 - 1.8e-12 47.5 0.1 4.5e-12 46.1 0.1 1.8 1 0 0 1 1 1 1 PCI domain Apc5 PF12862.2 CCV00301.1 - 0.0052 16.5 0.5 0.017 14.9 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 CCV00301.1 - 0.031 14.1 2.7 2.3 8.2 0.8 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCV00301.1 - 0.032 14.1 1.5 0.75 9.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2893 PF11459.3 CCV00301.1 - 0.055 13.2 0.3 9.1 6.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) TPR_16 PF13432.1 CCV00301.1 - 0.2 12.4 2.7 5.3 7.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCV00302.1 - 5.9e-10 38.6 8.7 7e-09 35.2 0.0 3.4 3 0 0 3 3 3 2 TPR repeat DnaJ PF00226.26 CCV00302.1 - 7.8e-05 22.3 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain UBA PF00627.26 CCV00302.1 - 0.0003 20.5 0.0 0.0039 16.9 0.0 2.6 3 0 0 3 3 3 1 UBA/TS-N domain TPR_1 PF00515.23 CCV00302.1 - 0.00044 19.7 0.2 0.32 10.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCV00302.1 - 0.039 13.9 6.2 0.56 10.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCV00302.1 - 0.065 13.1 8.9 1.7 8.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat VHS PF00790.14 CCV00303.1 - 1.2e-35 122.2 3.0 1.2e-35 122.2 1.2 1.6 2 0 0 2 2 2 1 VHS domain SH3_9 PF14604.1 CCV00303.1 - 2.3e-16 59.0 0.5 4.9e-16 58.0 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCV00303.1 - 2.1e-15 55.8 0.1 3.9e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCV00303.1 - 5.6e-12 44.9 0.1 1.1e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 CCV00303.1 - 2.2e-05 24.3 2.7 4.8e-05 23.2 0.8 2.3 2 0 0 2 2 2 1 GAT domain UIM PF02809.15 CCV00303.1 - 0.0021 17.4 2.9 0.0021 17.4 2.0 2.3 2 0 0 2 2 2 1 Ubiquitin interaction motif DUF2419 PF10343.4 CCV00304.1 - 0.12 11.6 0.0 0.49 9.6 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2419) DEP PF00610.16 CCV00305.1 - 0.0067 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) UCH_1 PF13423.1 CCV00306.1 - 8e-31 107.5 0.0 1.4e-30 106.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 CCV00306.1 - 8.7e-14 52.1 0.0 1.8e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 CCV00306.1 - 0.0058 15.7 0.0 0.25 10.4 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FlaG PF03646.10 CCV00306.1 - 0.053 13.6 0.0 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 FlaG protein Paf1 PF03985.8 CCV00307.1 - 2.8e-36 125.2 0.1 1.1e-23 83.7 0.0 2.1 2 0 0 2 2 2 2 Paf1 Smr PF01713.16 CCV00308.1 - 1.4e-09 37.9 0.0 3.5e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 CCV00308.1 - 3.2e-05 23.4 7.8 0.00054 19.5 0.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 CCV00308.1 - 0.0038 16.6 3.2 0.68 9.4 0.5 2.4 2 0 0 2 2 2 2 Putative zinc-finger domain LIN37 PF15306.1 CCV00308.1 - 8.5 6.3 5.9 3.7 7.5 0.2 2.5 2 1 0 2 2 2 0 LIN37 Tim44 PF04280.10 CCV00309.1 - 6.9e-29 100.7 0.0 6.8e-28 97.5 0.0 2.6 4 0 0 4 4 4 1 Tim44-like domain Seryl_tRNA_N PF02403.17 CCV00309.1 - 0.012 15.5 1.4 0.025 14.6 1.0 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CIA30 PF08547.7 CCV00310.1 - 1.8e-17 63.6 0.0 1.4e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Serglycin PF04360.7 CCV00310.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Serglycin Lipase_3 PF01764.20 CCV00312.1 - 8.4e-24 83.7 0.0 1.2e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CCV00312.1 - 0.0044 16.4 0.0 0.045 13.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_9 PF10081.4 CCV00312.1 - 0.0049 15.6 0.7 0.035 12.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta-hydrolase family DUF676 PF05057.9 CCV00312.1 - 0.0057 15.9 0.0 0.0087 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CCV00312.1 - 0.012 15.2 0.1 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 CCV00312.1 - 0.022 14.5 0.0 0.061 13.0 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Cutinase PF01083.17 CCV00312.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.2 CCV00312.1 - 0.026 14.3 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.6 CCV00312.1 - 0.093 11.8 0.1 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 CCV00312.1 - 0.097 12.0 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 CCV00312.1 - 0.11 11.4 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF155 PF02582.9 CCV00313.1 - 6.2e-22 78.3 0.4 9.3e-20 71.2 0.3 2.0 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ALG3 PF05208.8 CCV00314.1 - 3.9e-79 266.5 9.3 5.1e-79 266.1 6.4 1.0 1 0 0 1 1 1 1 ALG3 protein DUF218 PF02698.12 CCV00315.1 - 0.00074 19.0 0.0 0.075 12.5 0.0 2.2 2 0 0 2 2 2 2 DUF218 domain UPF0121 PF03661.8 CCV00316.1 - 4.4e-24 85.0 3.9 5.7e-24 84.6 2.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) RNA_pol_Rpb1_1 PF04997.7 CCV00317.1 - 3e-105 352.2 0.0 4e-105 351.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 CCV00317.1 - 2.5e-103 345.1 0.0 3.7e-103 344.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CCV00317.1 - 4.4e-69 231.6 0.0 7.7e-69 230.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CCV00317.1 - 3.8e-60 202.8 0.0 7.3e-60 201.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.7 CCV00317.1 - 1.4e-46 157.5 0.6 3.3e-46 156.3 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.13 CCV00317.1 - 3.5e-46 156.8 0.0 7.5e-46 155.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CCV00317.1 - 3.3e-37 126.5 0.0 7.7e-37 125.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DGOK PF05035.7 CCV00319.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase Gly-zipper_OmpA PF13436.1 CCV00319.1 - 0.51 10.0 3.5 1.3 8.7 0.2 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Pkinase PF00069.20 CCV00320.1 - 3.1e-66 223.1 0.0 2.1e-65 220.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Abhydrolase_3 PF07859.8 CCV00320.1 - 7.1e-46 156.4 0.3 2.2e-45 154.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pkinase_Tyr PF07714.12 CCV00320.1 - 2e-27 95.9 0.0 3.5e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2424 PF10340.4 CCV00320.1 - 5.6e-11 41.6 0.0 3.7e-10 39.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CCV00320.1 - 0.00011 21.9 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family YrbL-PhoP_reg PF10707.4 CCV00320.1 - 0.0084 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 CCV00320.1 - 0.01 14.9 0.0 0.029 13.4 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCV00320.1 - 0.059 12.7 0.1 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family COesterase PF00135.23 CCV00320.1 - 0.073 11.7 0.0 8.1 5.0 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family NAC PF01849.13 CCV00321.1 - 3.5e-20 71.2 0.0 8.4e-20 70.0 0.0 1.7 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 CCV00321.1 - 0.00011 21.8 0.1 0.00019 21.1 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CCV00321.1 - 0.069 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain Proteasome PF00227.21 CCV00322.1 - 5.3e-59 198.7 0.0 7.5e-59 198.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCV00322.1 - 8.1e-14 50.6 0.1 8.1e-14 50.6 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SNARE_assoc PF09335.6 CCV00323.1 - 6e-19 68.4 9.2 9.7e-19 67.7 2.6 2.4 2 0 0 2 2 2 2 SNARE associated Golgi protein DUF3100 PF11299.3 CCV00323.1 - 0.016 14.3 0.3 0.047 12.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3100) PUF PF00806.14 CCV00324.1 - 7.4e-10 37.7 0.0 0.00017 20.8 0.0 3.2 3 0 0 3 3 3 2 Pumilio-family RNA binding repeat RNase_PH PF01138.16 CCV00325.1 - 6.3e-21 75.0 0.0 8.5e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ABC_tran PF00005.22 CCV00326.1 - 1.1e-43 148.7 0.0 1.6e-21 77.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 CCV00326.1 - 9.3e-24 83.0 3.4 9.3e-24 83.0 2.4 3.1 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.1 CCV00326.1 - 2.1e-16 60.7 0.4 2.7e-05 24.2 0.0 4.5 3 1 0 4 4 4 3 AAA domain GHMP_kinases_N PF00288.21 CCV00326.1 - 2.5e-13 49.8 2.3 9.1e-13 48.0 1.6 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain SMC_N PF02463.14 CCV00326.1 - 3.7e-08 32.8 0.0 0.02 14.0 0.0 4.2 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CCV00326.1 - 7.4e-08 32.6 0.2 0.013 15.6 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCV00326.1 - 3.8e-07 29.5 0.1 0.011 15.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CCV00326.1 - 2.1e-06 28.5 0.3 0.13 13.1 0.0 3.5 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.18 CCV00326.1 - 3.4e-06 26.9 0.0 0.034 14.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 CCV00326.1 - 8.3e-06 25.0 0.0 0.046 12.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 CCV00326.1 - 1.7e-05 25.2 0.0 0.3 11.5 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 CCV00326.1 - 4.8e-05 23.0 0.1 0.19 11.3 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 CCV00326.1 - 6.8e-05 22.8 0.3 0.59 10.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain GHMP_kinases_C PF08544.8 CCV00326.1 - 0.00021 21.4 0.1 0.00081 19.5 0.1 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal MobB PF03205.9 CCV00326.1 - 0.00028 20.5 0.0 0.27 10.9 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 CCV00326.1 - 0.00089 18.4 0.1 0.39 9.7 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 CCV00326.1 - 0.00092 18.7 0.1 0.82 9.0 0.0 3.1 3 0 0 3 3 2 1 AAA-like domain ArgK PF03308.11 CCV00326.1 - 0.00093 18.0 0.0 0.41 9.3 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_23 PF13476.1 CCV00326.1 - 0.001 19.4 3.7 0.96 9.7 0.0 3.7 4 0 0 4 4 3 1 AAA domain SbcCD_C PF13558.1 CCV00326.1 - 0.0018 18.1 0.1 0.39 10.6 0.1 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 CCV00326.1 - 0.0027 17.5 0.0 1.1 9.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCV00326.1 - 0.0038 17.5 0.0 7.4 6.8 0.0 3.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 CCV00326.1 - 0.0042 17.2 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 CCV00326.1 - 0.0047 16.3 0.0 3.7 6.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CCV00326.1 - 0.0066 15.3 0.0 0.02 13.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 CCV00326.1 - 0.0082 15.9 0.5 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF815 PF05673.8 CCV00326.1 - 0.014 14.3 0.0 0.3 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 CCV00326.1 - 0.023 14.5 0.0 12 5.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 CCV00326.1 - 0.029 13.8 0.0 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 CCV00326.1 - 0.038 14.1 0.0 6.5 6.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CCV00326.1 - 0.22 11.1 0.4 26 4.3 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase NTPase_1 PF03266.10 CCV00326.1 - 0.25 11.0 0.0 18 4.9 0.0 2.5 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.18 CCV00326.1 - 0.61 9.8 5.0 1.8 8.3 0.1 2.9 4 0 0 4 4 2 0 Dynamin family AAA_16 PF13191.1 CCV00326.1 - 2.4 8.1 13.7 4 7.3 0.4 4.3 4 2 0 4 4 3 0 AAA ATPase domain BSD PF03909.12 CCV00327.1 - 1.2e-18 66.5 0.0 3.6e-15 55.4 0.1 2.6 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 CCV00327.1 - 1.2e-12 47.3 0.0 2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain CDC37_N PF03234.9 CCV00328.1 - 1.7e-45 155.5 4.3 1.7e-45 155.5 3.0 1.8 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 CCV00328.1 - 7.8e-27 93.8 2.8 6.6e-23 81.0 0.5 2.5 2 0 0 2 2 2 2 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 CCV00328.1 - 2e-18 66.0 0.1 4.1e-17 61.8 0.0 2.8 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF3712 PF12505.3 CCV00331.1 - 9.7e-25 87.0 0.7 2.9e-24 85.4 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF3712 PF12505.3 CCV00332.1 - 3.8e-41 140.0 15.0 5.2e-25 87.8 0.5 5.2 5 0 0 5 5 5 4 Protein of unknown function (DUF3712) LEA_2 PF03168.8 CCV00332.1 - 5.6e-07 29.8 1.4 0.0038 17.5 0.1 3.4 3 0 0 3 3 3 2 Late embryogenesis abundant protein Actin PF00022.14 CCV00333.1 - 1.3e-27 96.2 0.0 1.3e-18 66.6 0.0 2.2 2 0 0 2 2 2 2 Actin NAD_binding_5 PF07994.7 CCV00334.1 - 2.4e-111 371.9 0.0 2.8e-111 371.7 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CCV00334.1 - 8.9e-44 147.8 0.0 1.5e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Ala_racemase_N PF01168.15 CCV00335.1 - 1.2e-25 90.4 0.6 8.2e-24 84.3 0.1 2.4 2 1 0 2 2 2 1 Alanine racemase, N-terminal domain DUF89 PF01937.14 CCV00335.1 - 6.8e-11 41.5 0.0 1.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF89 Sulfate_transp PF00916.15 CCV00337.1 - 9.7e-46 156.0 6.0 2.1e-45 154.8 4.2 1.6 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 CCV00337.1 - 6.2e-14 51.5 0.0 1.2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 CCV00337.1 - 7.9e-11 41.4 0.7 7.9e-10 38.1 0.0 2.4 1 1 1 2 2 2 1 STAS domain DUF2414 PF10309.4 CCV00338.1 - 7.1e-09 35.2 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DEAD PF00270.24 CCV00339.1 - 4e-44 150.0 1.0 1.4e-43 148.3 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCV00339.1 - 1.7e-27 95.0 0.4 5.3e-27 93.4 0.3 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CCV00339.1 - 0.00012 21.7 0.1 0.00036 20.2 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 CCV00339.1 - 0.00014 21.7 0.0 0.00037 20.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CCV00339.1 - 0.0045 16.6 0.1 0.026 14.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCV00339.1 - 0.024 14.8 0.0 0.077 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 CCV00339.1 - 0.042 12.9 0.2 0.11 11.6 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Fanconi_A PF03511.9 CCV00339.1 - 0.061 13.1 0.1 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Fanconi anaemia group A protein CMS1 PF14617.1 CCV00339.1 - 0.095 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MIR PF02815.14 CCV00340.1 - 9.6e-22 77.4 1.5 1.1e-20 73.9 1.0 2.0 1 1 0 1 1 1 1 MIR domain PMT PF02366.13 CCV00340.1 - 0.00052 19.4 2.8 0.00052 19.4 1.9 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.27 CCV00341.1 - 9.8e-58 190.1 15.9 1.2e-14 53.4 1.0 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 CCV00341.1 - 8.7e-08 30.7 8.5 0.0028 15.8 0.0 4.7 1 1 4 5 5 5 3 Nucleoporin Nup120/160 DUF3312 PF11768.3 CCV00341.1 - 3.9e-06 25.3 0.0 6.3e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 CCV00341.1 - 8.4e-06 24.7 5.0 0.17 10.6 1.2 5.2 1 1 1 2 2 2 1 Nup133 N terminal like GSDH PF07995.6 CCV00341.1 - 0.0027 16.8 0.0 3.8 6.4 0.0 3.3 3 1 0 4 4 4 2 Glucose / Sorbosone dehydrogenase Coatomer_WDAD PF04053.9 CCV00341.1 - 0.0035 16.2 0.0 0.0047 15.7 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region PQQ_3 PF13570.1 CCV00341.1 - 0.27 11.5 3.1 10 6.5 0.0 3.9 2 1 1 3 3 3 0 PQQ-like domain dsrm PF00035.20 CCV00342.1 - 1e-07 32.4 0.0 1.6e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 CCV00342.1 - 2.6e-06 27.8 0.0 4.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CCV00342.1 - 1.8e-05 24.6 0.0 3.9e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease-III-like SRP54 PF00448.17 CCV00343.1 - 5e-35 120.7 0.0 2.9e-33 114.9 0.0 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 CCV00343.1 - 3.9e-11 42.8 6.2 6.1e-11 42.2 4.3 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 CCV00343.1 - 3.8e-06 26.4 0.0 3.8e-06 26.4 0.0 1.8 2 0 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 CCV00343.1 - 4.7e-06 25.5 0.0 1.2e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 ArgK protein SRP54_N PF02881.14 CCV00343.1 - 0.00012 22.0 0.1 0.00031 20.7 0.1 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MobB PF03205.9 CCV00343.1 - 0.0015 18.2 0.0 0.0049 16.5 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 CCV00343.1 - 0.0041 17.2 0.0 0.035 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 CCV00343.1 - 0.031 13.3 0.0 0.44 9.5 0.0 2.4 1 1 0 1 1 1 0 Anion-transporting ATPase FlgM PF04316.8 CCV00343.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Fer4_NifH PF00142.13 CCV00343.1 - 0.078 12.1 0.1 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ETF PF01012.16 CCV00343.1 - 0.097 12.3 0.8 0.28 10.8 0.2 2.0 2 0 0 2 2 2 0 Electron transfer flavoprotein domain AAA_10 PF12846.2 CCV00343.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.10 CCV00343.1 - 0.12 12.0 0.0 0.34 10.6 0.0 1.7 1 1 0 1 1 1 0 NTPase Na_H_Exchanger PF00999.16 CCV00344.1 - 1.4e-07 30.3 0.5 1.8e-07 30.0 0.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Chibby PF14645.1 CCV00344.1 - 0.089 12.6 0.1 0.24 11.3 0.1 1.7 1 1 0 1 1 1 0 Chibby family Abhydrolase_6 PF12697.2 CCV00345.1 - 9.8e-25 87.7 1.7 2e-24 86.7 1.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCV00345.1 - 7.1e-20 71.5 0.4 2.6e-19 69.7 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCV00345.1 - 1.1e-11 44.6 0.0 6.5e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCV00345.1 - 3.8e-05 23.4 0.0 0.00015 21.5 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CCV00345.1 - 6.3e-05 22.2 0.1 0.055 12.6 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family LIP PF03583.9 CCV00345.1 - 0.0019 17.4 0.0 0.011 14.9 0.0 1.9 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_2 PF02230.11 CCV00345.1 - 0.0024 17.3 0.0 0.012 15.0 0.0 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S10 PF00450.17 CCV00345.1 - 0.0085 15.3 0.1 0.078 12.1 0.0 2.0 2 0 0 2 2 2 1 Serine carboxypeptidase Abhydrolase_4 PF08386.5 CCV00345.1 - 0.05 13.4 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 TAP-like protein SWIRM PF04433.12 CCV00346.1 - 3.3e-35 120.0 0.1 7.7e-35 118.8 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 CCV00346.1 - 6.3e-08 32.0 1.7 1.1e-07 31.2 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 CCV00346.1 - 1.4e-07 31.4 0.1 4e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCV00346.1 - 1.4e-06 28.2 0.2 5.7e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain RhoGAP PF00620.22 CCV00347.1 - 6.7e-41 139.4 0.0 1.5e-40 138.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 CCV00347.1 - 1.2e-10 41.4 0.0 1.3e-09 38.0 0.0 2.4 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 CCV00347.1 - 1.5e-05 25.0 0.0 5.6e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif Cellulase PF00150.13 CCV00348.1 - 2.7e-18 66.1 8.0 6.4e-18 64.9 5.5 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.13 CCV00349.1 - 1.9e-08 33.8 0.0 2.6e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TPR_2 PF07719.12 CCV00351.1 - 1.2e-07 31.0 10.3 0.72 9.9 0.0 8.2 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCV00351.1 - 1.2e-07 32.2 7.3 12 6.7 0.4 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCV00351.1 - 1.2e-07 31.2 7.9 1.5 8.5 0.0 7.3 7 0 0 7 7 7 2 TPR repeat TPR_12 PF13424.1 CCV00351.1 - 1.5e-07 31.2 10.2 2.8 7.9 0.0 7.6 8 2 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCV00351.1 - 8.8e-06 25.9 1.5 5.8 7.3 0.5 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCV00351.1 - 9.9e-06 25.7 18.3 6.7 7.6 0.0 10.3 10 3 3 13 13 12 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CCV00351.1 - 0.00016 21.4 10.8 0.56 9.9 0.7 6.6 8 0 0 8 8 8 1 Mad3/BUB1 homology region 1 TPR_7 PF13176.1 CCV00351.1 - 0.00051 19.6 7.6 5.7 6.9 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat MIT PF04212.13 CCV00351.1 - 0.0097 15.7 2.3 0.19 11.6 0.1 3.9 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 CCV00351.1 - 0.11 12.7 9.3 27 5.2 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCV00351.1 - 0.25 11.8 10.2 1.2e+02 3.4 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCV00351.1 - 0.71 9.5 11.5 1.5 8.5 0.0 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCV00351.1 - 0.89 9.4 10.9 31 4.6 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat RRM_6 PF14259.1 CCV00352.1 - 8.4e-07 28.8 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCV00352.1 - 5.5e-06 25.9 0.0 8.2e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCV00352.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 CCV00352.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif 2 WD40 PF00400.27 CCV00353.1 - 6.8e-21 73.3 1.2 4.9e-09 35.7 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCV00353.1 - 0.00013 20.8 0.0 0.066 11.9 0.0 3.0 1 1 1 2 2 2 2 Nup133 N terminal like Striatin PF08232.7 CCV00353.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Striatin family Med26 PF08711.6 CCV00354.1 - 1.6e-08 33.8 0.0 2.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ribosomal_S4 PF00163.14 CCV00355.1 - 5.5e-28 97.2 0.4 9.3e-28 96.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCV00355.1 - 7.8e-14 50.8 0.6 7.8e-14 50.8 0.4 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 CCV00356.1 - 3.2e-35 119.9 5.4 1.4e-34 117.8 3.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e SH3_2 PF07653.12 CCV00356.1 - 0.015 14.7 0.1 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Amidohydro_4 PF13147.1 CCV00357.1 - 2.5e-18 67.0 3.9 2.5e-18 67.0 2.7 2.9 2 1 1 3 3 3 1 Amidohydrolase Amidohydro_5 PF13594.1 CCV00357.1 - 2.7e-12 46.2 0.1 2.6e-10 39.9 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 CCV00357.1 - 1e-10 41.8 0.0 1.8e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 CCV00357.1 - 2.1e-07 30.5 1.2 0.00019 20.8 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Ank_2 PF12796.2 CCV00358.1 - 6.5e-14 52.0 1.7 6e-12 45.7 0.2 2.9 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCV00358.1 - 8.4e-14 51.6 1.2 3.3e-09 37.0 0.6 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CCV00358.1 - 2.3e-10 39.7 1.3 1.6e-06 27.6 0.0 4.1 4 1 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 CCV00358.1 - 9.6e-10 37.7 5.6 5.5e-05 23.0 0.0 4.3 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 CCV00358.1 - 1.3e-08 34.8 4.2 0.00011 22.2 0.1 3.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Pan_kinase PF03309.9 CCV00358.1 - 0.14 11.6 0.1 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Type III pantothenate kinase Sds3 PF08598.6 CCV00359.1 - 7.1e-20 71.4 6.1 7.1e-20 71.4 4.2 2.1 2 1 0 2 2 2 1 Sds3-like BCDHK_Adom3 PF10436.4 CCV00360.1 - 2.3e-58 196.3 0.0 3.3e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCV00360.1 - 8e-12 44.8 0.0 1.4e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CCV00360.1 - 3e-06 26.9 0.0 5.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mt_ATP-synt_B PF05405.9 CCV00361.1 - 3e-42 143.8 9.1 3.6e-42 143.5 6.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DASH_Duo1 PF08651.5 CCV00361.1 - 0.026 14.0 1.5 6.6 6.3 0.0 2.7 2 1 1 3 3 3 0 DASH complex subunit Duo1 Transpep_BrtH PF14399.1 CCV00361.1 - 0.048 12.9 0.7 0.082 12.1 0.0 1.6 2 0 0 2 2 2 0 NlpC/p60-like transpeptidase DUF573 PF04504.9 CCV00361.1 - 0.075 13.3 0.7 2.6 8.3 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function, DUF573 OEP PF02321.13 CCV00361.1 - 3.8 7.0 12.8 0.36 10.3 5.9 1.4 2 0 0 2 2 2 0 Outer membrane efflux protein Pkinase PF00069.20 CCV00362.1 - 3.7e-69 232.7 0.0 4.3e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCV00362.1 - 3e-33 115.0 0.0 5.1e-33 114.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCV00362.1 - 0.027 13.4 0.0 0.66 8.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 CCV00362.1 - 0.14 11.8 0.0 0.14 11.8 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family VPS9 PF02204.13 CCV00363.1 - 5e-28 97.1 0.0 7.4e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RRM_6 PF14259.1 CCV00364.1 - 5.6e-05 23.0 0.0 0.02 14.8 0.0 3.6 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCV00364.1 - 0.00015 21.3 0.1 0.081 12.5 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_CoA_synt_N PF01154.12 CCV00365.1 - 9.8e-86 285.7 0.0 1.4e-85 285.2 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 CCV00365.1 - 1e-77 261.4 0.1 1.5e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.5 CCV00365.1 - 0.00053 19.9 0.0 0.024 14.6 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AAA PF00004.24 CCV00367.1 - 8.7e-84 278.3 0.0 1.3e-41 141.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCV00367.1 - 7.6e-13 48.0 0.0 8.2e-08 31.5 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCV00367.1 - 1.1e-12 48.3 2.5 7.5e-06 26.0 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 CCV00367.1 - 3.7e-12 46.1 0.1 1e-05 25.2 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCV00367.1 - 1.1e-10 41.7 0.5 3e-05 24.1 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 CCV00367.1 - 2.3e-10 40.6 0.0 6.8e-06 26.0 0.0 2.5 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CCV00367.1 - 4.9e-08 32.9 0.0 0.00014 21.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CCV00367.1 - 1.3e-07 32.4 0.0 0.00031 21.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCV00367.1 - 1.8e-07 31.0 0.0 0.00042 20.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 CCV00367.1 - 5.2e-07 28.7 0.0 0.0062 15.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 CCV00367.1 - 1.1e-06 27.8 0.0 0.00015 20.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 CCV00367.1 - 5.1e-06 26.6 0.0 0.0083 16.2 0.0 2.4 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 CCV00367.1 - 1e-05 25.1 3.4 0.0024 17.5 0.0 4.4 4 0 0 4 4 4 1 Part of AAA domain AAA_28 PF13521.1 CCV00367.1 - 1.8e-05 24.8 0.5 0.042 13.7 0.1 3.3 3 1 0 3 3 3 1 AAA domain AAA_24 PF13479.1 CCV00367.1 - 2.3e-05 24.1 0.0 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCV00367.1 - 0.00016 20.8 0.1 0.1 11.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CCV00367.1 - 0.00037 19.9 5.4 0.11 11.8 0.1 3.6 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.12 CCV00367.1 - 0.00037 19.9 0.0 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_3 PF07726.6 CCV00367.1 - 0.00044 19.8 0.0 0.39 10.3 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCV00367.1 - 0.0038 16.8 0.0 0.18 11.4 0.0 3.5 4 0 0 4 4 4 1 NACHT domain AAA_18 PF13238.1 CCV00367.1 - 0.0059 16.9 0.0 0.1 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CCV00367.1 - 0.0059 16.2 0.0 0.42 10.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 CCV00367.1 - 0.0067 16.4 0.0 2 8.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.10 CCV00367.1 - 0.015 14.0 0.0 0.16 10.6 0.0 2.2 2 1 1 3 3 3 0 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 CCV00367.1 - 0.016 14.1 0.0 0.052 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IPT PF01745.11 CCV00367.1 - 0.017 14.2 0.1 0.81 8.8 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Arch_ATPase PF01637.13 CCV00367.1 - 0.022 14.4 0.0 0.53 9.9 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 CCV00367.1 - 0.031 13.9 0.2 0.2 11.3 0.0 2.3 2 2 2 4 4 3 0 NTPase ABC_tran PF00005.22 CCV00367.1 - 0.036 14.3 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter SKI PF01202.17 CCV00367.1 - 0.039 13.8 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase Sigma54_activat PF00158.21 CCV00367.1 - 0.043 13.2 0.0 3.7 6.9 0.0 3.2 4 0 0 4 4 3 0 Sigma-54 interaction domain KaiC PF06745.8 CCV00367.1 - 0.046 12.8 0.0 3.1 6.8 0.0 2.5 2 0 0 2 2 2 0 KaiC DAP3 PF10236.4 CCV00367.1 - 0.071 12.0 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 UPF0079 PF02367.12 CCV00367.1 - 0.12 12.0 0.1 0.61 9.7 0.0 2.1 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 CCV00367.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.3 3 0 0 3 3 2 0 AAA domain Parvo_NS1 PF01057.12 CCV00367.1 - 0.16 10.7 0.0 0.57 8.9 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 CCV00367.1 - 0.17 11.1 0.3 0.76 8.9 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein FAD_binding_3 PF01494.14 CCV00368.1 - 6.6e-16 58.3 7.4 6.2e-09 35.3 0.8 3.1 3 0 0 3 3 3 2 FAD binding domain NAD_binding_9 PF13454.1 CCV00368.1 - 0.00036 20.3 0.1 0.0012 18.6 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 CCV00368.1 - 0.00094 18.0 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 CCV00368.1 - 0.001 18.0 0.9 0.031 13.2 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Hpt PF01627.18 CCV00368.1 - 0.054 13.4 1.0 0.17 11.8 0.7 1.8 1 0 0 1 1 1 0 Hpt domain Pyr_redox_3 PF13738.1 CCV00368.1 - 0.073 13.1 0.2 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SMC_N PF02463.14 CCV00370.1 - 4.1e-63 212.5 0.0 5.4e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCV00370.1 - 2e-28 98.7 3.2 2.1e-28 98.6 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CCV00370.1 - 2.9e-16 60.4 11.0 2.9e-16 60.4 7.6 4.8 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 CCV00370.1 - 1.5e-12 48.1 0.0 2.6e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CCV00370.1 - 3.1e-12 46.2 0.0 2.6e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain ABC_tran PF00005.22 CCV00370.1 - 4.2e-06 27.0 6.6 0.062 13.5 0.0 4.7 5 1 0 5 5 5 2 ABC transporter AAA_29 PF13555.1 CCV00370.1 - 7.8e-05 22.1 0.0 0.00045 19.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF106 PF01956.11 CCV00371.1 - 1.2e-49 168.0 0.3 1.9e-49 167.4 0.2 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF106 Ceramidase PF05875.7 CCV00372.1 - 2.2e-77 259.7 6.0 2.7e-77 259.4 4.2 1.0 1 0 0 1 1 1 1 Ceramidase Neurensin PF14927.1 CCV00372.1 - 0.035 13.4 2.3 0.15 11.4 0.0 2.6 3 0 0 3 3 3 0 Neurensin DUF1691 PF07950.6 CCV00372.1 - 8.5 6.3 9.1 7.4 6.5 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1691) Pinin_SDK_memA PF04696.8 CCV00373.1 - 0.045 13.3 10.5 0.87 9.1 0.0 3.0 3 1 0 3 3 3 0 pinin/SDK/memA/ protein conserved region BAR PF03114.13 CCV00373.1 - 0.11 12.0 2.0 0.23 10.9 0.4 1.8 2 0 0 2 2 2 0 BAR domain TPR_MLP1_2 PF07926.7 CCV00373.1 - 5.8 6.6 9.9 0.7 9.6 1.7 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1348 PF07080.6 CCV00374.1 - 3.2e-52 176.1 2.9 3.6e-52 175.9 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 CCV00374.1 - 1.1e-06 28.9 0.1 1.8e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 CCV00374.1 - 0.00086 19.4 0.4 0.017 15.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 CCV00374.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase E1-E2_ATPase PF00122.15 CCV00375.1 - 2.1e-19 69.5 0.0 4e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CCV00375.1 - 5.9e-19 68.9 0.0 1e-18 68.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCV00375.1 - 4e-12 45.9 0.0 9.9e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 CCV00375.1 - 8.3e-12 45.9 4.4 4.6e-10 40.2 2.3 3.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCV00375.1 - 0.0053 16.9 0.1 0.012 15.8 0.1 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCV00375.1 - 0.01 15.3 0.1 0.039 13.5 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase RNase_T PF00929.19 CCV00377.1 - 3.1e-23 82.8 0.0 4.4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CCV00377.1 - 0.0044 16.5 0.0 0.0097 15.3 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease RabGAP-TBC PF00566.13 CCV00378.1 - 1.6e-47 161.7 0.0 2.1e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNA_pol_Rpb8 PF03870.10 CCV00379.1 - 6.9e-41 139.6 0.0 8.2e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 polyprenyl_synt PF00348.12 CCV00380.1 - 2.4e-46 157.7 0.0 2.9e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase FGGY_C PF02782.11 CCV00381.1 - 5.6e-18 65.2 0.1 2e-17 63.4 0.1 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CCV00381.1 - 1.2e-15 57.5 0.0 2.8e-12 46.4 0.0 3.2 3 0 0 3 3 3 3 FGGY family of carbohydrate kinases, N-terminal domain HEAT_EZ PF13513.1 CCV00382.1 - 1.9e-26 91.8 29.5 8.7e-11 41.9 0.0 12.2 8 3 6 14 14 14 6 HEAT-like repeat HEAT_2 PF13646.1 CCV00382.1 - 1e-22 80.1 4.2 7e-06 26.2 0.0 8.0 5 3 4 9 9 9 5 HEAT repeats HEAT PF02985.17 CCV00382.1 - 9.2e-21 72.0 20.9 0.0011 18.9 0.0 10.3 11 0 0 11 11 10 5 HEAT repeat Vac14_Fab1_bd PF12755.2 CCV00382.1 - 2.6e-11 43.7 0.0 0.0039 17.5 0.0 5.9 6 2 1 7 7 7 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 CCV00382.1 - 1.5e-05 24.6 13.1 0.73 9.7 0.0 8.3 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat DUF3437 PF11919.3 CCV00382.1 - 2.9e-05 23.7 0.1 0.15 11.7 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) IBN_N PF03810.14 CCV00382.1 - 6.5e-05 22.7 0.2 0.001 18.9 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain MMS19_C PF12460.3 CCV00382.1 - 0.00012 20.9 6.9 0.47 9.1 0.4 4.6 3 1 1 4 4 4 3 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 CCV00382.1 - 0.003 17.4 0.1 4 7.2 0.0 4.5 3 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 CCV00382.1 - 0.012 13.9 0.3 0.69 8.1 0.1 3.1 3 0 0 3 3 3 0 Adaptin N terminal region Ipi1_N PF12333.3 CCV00382.1 - 0.039 13.9 0.5 0.95 9.4 0.0 3.4 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Xpo1 PF08389.7 CCV00382.1 - 0.07 13.0 0.2 6.6 6.6 0.0 3.6 4 0 0 4 4 4 0 Exportin 1-like protein Cpn60_TCP1 PF00118.19 CCV00383.1 - 1.8e-137 458.9 0.0 2.1e-137 458.7 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Saccharop_dh PF03435.13 CCV00384.1 - 5.1e-21 75.0 0.4 7.4e-21 74.5 0.3 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 CCV00384.1 - 0.00041 19.6 0.3 0.00065 19.0 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 CCV00384.1 - 0.018 15.3 0.1 0.055 13.7 0.0 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain UPF0086 PF01868.11 CCV00385.1 - 1.1e-11 44.1 0.0 2.5e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function UPF0086 MRP-S26 PF14943.1 CCV00385.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF3972 PF13118.1 CCV00385.1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) E1-E2_ATPase PF00122.15 CCV00387.1 - 1.2e-72 243.6 2.8 2.8e-72 242.4 2.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCV00387.1 - 1.6e-35 122.2 1.3 1.6e-35 122.2 0.9 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCV00387.1 - 2.6e-35 122.7 0.7 5.5e-35 121.7 0.5 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCV00387.1 - 5.9e-17 62.4 0.0 1.5e-16 61.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCV00387.1 - 1.7e-15 56.6 0.0 3.8e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CCV00387.1 - 9.5e-13 47.4 0.0 2.5e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCV00387.1 - 5.3e-08 32.7 2.4 1.6e-05 24.6 0.5 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CCV00387.1 - 0.056 13.3 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Epimerase_2 PF02350.14 CCV00387.1 - 0.063 12.0 0.1 0.17 10.6 0.0 1.7 2 0 0 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase HSP70 PF00012.15 CCV00388.1 - 8.9e-55 185.7 6.9 4e-51 173.6 0.0 3.1 2 2 1 3 3 3 2 Hsp70 protein Latarcin PF10279.4 CCV00388.1 - 0.6 10.3 3.8 4.2 7.6 2.5 2.3 1 1 0 1 1 1 0 Latarcin precursor Peptidase_M1 PF01433.15 CCV00389.1 - 2e-62 211.5 0.0 2.9e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 IPPT PF01715.12 CCV00389.1 - 2.9e-50 170.6 0.6 2e-26 92.5 0.6 2.7 2 0 0 2 2 2 2 IPP transferase Leuk-A4-hydro_C PF09127.6 CCV00389.1 - 6.2e-36 123.1 0.0 1.6e-35 121.7 0.0 1.8 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 CCV00389.1 - 4.1e-13 49.4 0.0 1e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily ArgK PF03308.11 CCV00389.1 - 0.0014 17.4 0.0 0.0024 16.7 0.0 1.3 1 0 0 1 1 1 1 ArgK protein MobB PF03205.9 CCV00389.1 - 0.0015 18.2 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CCV00389.1 - 0.0019 19.0 0.1 0.01 16.6 0.0 2.4 2 0 0 2 2 1 1 AAA domain IPT PF01745.11 CCV00389.1 - 0.003 16.7 0.1 0.0058 15.8 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase IstB_IS21 PF01695.12 CCV00389.1 - 0.0036 16.7 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TrwB_AAD_bind PF10412.4 CCV00389.1 - 0.0098 14.5 0.0 0.029 13.0 0.0 1.7 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 CCV00389.1 - 0.021 14.6 5.6 0.15 11.8 0.0 3.6 3 1 0 4 4 3 0 AAA domain CbiA PF01656.18 CCV00389.1 - 0.025 13.9 0.1 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.1 CCV00389.1 - 0.026 14.2 0.1 0.07 12.8 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 CCV00389.1 - 0.045 12.9 0.1 0.085 12.0 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 CCV00389.1 - 0.048 13.3 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 CCV00389.1 - 0.072 13.0 1.2 0.23 11.4 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 CCV00389.1 - 0.086 12.9 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 CCV00389.1 - 0.11 11.9 0.1 0.35 10.2 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 CCV00389.1 - 0.2 11.4 0.1 0.5 10.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 Peptidase_M61 PF05299.7 CCV00389.1 - 0.69 9.9 4.8 2.9 7.8 1.3 3.2 2 1 0 2 2 2 0 M61 glycyl aminopeptidase PK PF00224.16 CCV00390.1 - 2.2e-154 513.2 2.0 2.7e-154 512.9 1.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CCV00390.1 - 3.8e-29 100.6 0.0 1.1e-28 99.0 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CCV00390.1 - 1e-05 24.5 0.4 3e-05 23.0 0.3 1.7 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 CCV00390.1 - 0.0025 16.7 0.1 0.065 12.1 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Peptidase_U32 PF01136.14 CCV00390.1 - 0.034 13.0 0.0 0.082 11.8 0.0 1.6 2 0 0 2 2 2 0 Peptidase family U32 Med5 PF08689.5 CCV00391.1 - 5.7e-09 34.2 0.0 8.7e-09 33.6 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit Med5 Methyltransf_11 PF08241.7 CCV00392.1 - 4.7e-13 49.4 0.0 1.1e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCV00392.1 - 6.1e-11 42.6 0.0 1.6e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCV00392.1 - 1.1e-08 34.7 0.0 2.1e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCV00392.1 - 3e-08 33.5 0.0 5.2e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCV00392.1 - 4.8e-08 32.4 0.0 7.7e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CCV00392.1 - 4.8e-05 23.6 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCV00392.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SNAP PF14938.1 CCV00393.1 - 1.2e-73 247.7 13.5 1.4e-73 247.5 9.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 CCV00393.1 - 0.0019 17.8 15.9 0.047 13.3 3.2 3.6 1 1 2 3 3 3 2 TPR repeat Spatacsin_C PF14649.1 CCV00393.1 - 0.0024 16.8 0.7 0.0024 16.8 0.5 1.8 1 1 1 2 2 2 1 Spatacsin C-terminus TPR_7 PF13176.1 CCV00393.1 - 0.0048 16.6 13.3 0.22 11.4 0.1 5.2 3 1 2 5 5 5 2 Tetratricopeptide repeat MIT PF04212.13 CCV00393.1 - 0.024 14.4 1.3 0.024 14.4 0.9 2.9 2 2 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 CCV00393.1 - 0.029 15.0 3.6 0.029 15.0 2.5 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCV00393.1 - 0.093 12.3 8.1 0.72 9.5 0.2 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCV00393.1 - 0.14 11.9 6.9 1.4 8.8 0.2 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCV00393.1 - 0.27 11.2 0.2 0.27 11.2 0.1 5.7 6 1 2 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCV00393.1 - 0.49 10.3 21.9 2.2 8.2 2.5 4.4 2 1 3 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 CCV00393.1 - 0.6 10.2 8.8 6.3 7.0 0.4 3.8 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CCV00393.1 - 0.62 9.9 9.1 23 4.9 1.6 3.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCV00393.1 - 1.8 9.2 16.9 27 5.5 0.0 6.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Remorin_C PF03763.8 CCV00393.1 - 2.3 7.8 6.3 16 5.0 1.8 2.4 2 0 0 2 2 2 0 Remorin, C-terminal region GatB_N PF02934.10 CCV00394.1 - 6.4e-106 353.4 0.0 8.4e-106 353.0 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 CCV00394.1 - 7.9e-24 84.0 0.0 1.1e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 GatB domain PTPA PF03095.10 CCV00395.1 - 5.5e-70 235.9 0.0 6.5e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein tRNA-synt_2b PF00587.20 CCV00396.1 - 5.3e-44 149.8 0.2 9.8e-44 148.9 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCV00396.1 - 9.8e-18 63.9 0.1 2.2e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 CCV00396.1 - 1.3e-16 60.2 0.0 2.7e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 CCV00396.1 - 1.6e-10 40.7 0.0 3.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF502 PF04367.8 CCV00396.1 - 0.077 12.7 0.0 0.6 9.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF502) Myb_Cef PF11831.3 CCV00398.1 - 0.0052 16.0 3.9 0.0052 16.0 2.7 2.8 2 1 1 3 3 3 1 pre-mRNA splicing factor component EcsC PF12787.2 CCV00398.1 - 0.06 12.7 11.0 0.1 11.9 7.6 1.4 1 0 0 1 1 1 0 EcsC protein family SQS_PSY PF00494.14 CCV00399.1 - 1.5e-34 119.5 0.0 2.5e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF2578 PF10843.3 CCV00399.1 - 0.023 14.3 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2578) Kri1_C PF12936.2 CCV00400.1 - 8.5e-26 89.7 0.1 8.5e-26 89.7 0.1 4.5 4 2 2 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 CCV00400.1 - 1.7e-24 85.9 12.9 1.7e-24 85.9 8.9 5.0 4 1 0 5 5 5 1 KRI1-like family DRIM PF07539.7 CCV00401.1 - 2.3e-34 117.8 0.0 1.1e-31 109.1 0.0 3.1 2 0 0 2 2 2 2 Down-regulated in metastasis DUF2454 PF10521.4 CCV00401.1 - 0.0077 15.2 0.0 0.37 9.7 0.0 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF2454) Sigma70_ner PF04546.8 CCV00401.1 - 0.01 15.4 0.3 0.028 14.0 0.2 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 CCV00401.1 - 0.07 12.9 0.8 0.23 11.2 0.6 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 CCV00401.1 - 2.5 7.6 10.3 5.4 6.5 7.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 CCV00401.1 - 4.5 5.8 12.0 10 4.7 8.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sel1 PF08238.7 CCV00402.1 - 6e-14 52.1 16.4 0.00033 21.1 0.1 7.2 8 0 0 8 8 8 5 Sel1 repeat DUF3528 PF12045.3 CCV00402.1 - 0.049 13.7 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3528) Aconitase PF00330.15 CCV00403.1 - 2.8e-69 233.7 0.1 2.8e-47 161.2 0.0 2.9 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCV00403.1 - 8.6e-21 74.4 0.0 1.8e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain IlvN PF07991.7 CCV00404.1 - 9.6e-45 151.9 0.0 1.4e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 CCV00404.1 - 6e-42 143.0 0.0 8.4e-42 142.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 CCV00404.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Metallophos PF00149.23 CCV00405.1 - 5.7e-10 38.9 0.3 9.8e-10 38.1 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase LSM PF01423.17 CCV00406.1 - 1.1e-09 37.7 0.0 1.7e-09 37.1 0.0 1.3 1 1 0 1 1 1 1 LSM domain WAC_Acf1_DNA_bd PF10537.4 CCV00407.1 - 2.7e-36 123.7 0.2 6.6e-36 122.5 0.1 1.7 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 CCV00407.1 - 2.3e-09 36.8 0.0 4.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 CCV00407.1 - 0.00011 21.9 0.4 0.00045 20.0 0.1 2.2 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 CCV00407.1 - 0.00012 21.8 0.4 0.00037 20.2 0.0 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 3 GAS PF13851.1 CCV00407.1 - 1.8 7.7 11.2 2.2 7.4 5.3 2.4 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Abhydrolase_6 PF12697.2 CCV00408.1 - 1.8e-23 83.6 9.9 2.3e-23 83.2 6.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCV00408.1 - 9.5e-15 54.6 0.0 1.9e-14 53.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCV00408.1 - 3.9e-10 39.6 0.0 3.5e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CCV00408.1 - 0.00011 21.9 0.1 0.011 15.6 0.1 2.3 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CCV00408.1 - 0.0018 17.5 0.0 0.56 9.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.15 CCV00408.1 - 0.0042 17.3 0.0 0.0091 16.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 CCV00408.1 - 0.0067 16.0 0.1 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein FSH1 PF03959.8 CCV00408.1 - 0.032 13.6 0.0 0.21 11.0 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF676 PF05057.9 CCV00408.1 - 0.037 13.3 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) GAGA_bind PF06217.7 CCV00409.1 - 0.0073 16.3 1.3 0.0078 16.2 0.9 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family DUF3347 PF11827.3 CCV00409.1 - 0.034 14.1 2.3 0.041 13.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Peptidase_S49_N PF08496.5 CCV00409.1 - 0.22 11.3 1.6 0.28 10.9 1.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OmpH PF03938.9 CCV00409.1 - 0.25 11.2 5.6 0.27 11.1 3.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_L31e PF01198.14 CCV00410.1 - 1.3e-35 120.8 3.7 1.6e-35 120.5 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e GTP_EFTU PF00009.22 CCV00411.1 - 4.8e-60 202.2 0.5 4.8e-60 202.2 0.3 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCV00411.1 - 1.7e-28 98.6 0.0 3.8e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCV00411.1 - 3e-15 56.0 5.0 8.3e-15 54.6 3.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCV00411.1 - 9.2e-06 25.5 0.0 2.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CCV00411.1 - 0.0002 20.9 0.7 0.00047 19.7 0.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 CCV00411.1 - 0.0012 19.2 0.0 0.0091 16.4 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 CCV00411.1 - 0.044 13.2 0.2 8.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CCV00411.1 - 0.052 13.8 0.1 0.83 9.9 0.0 2.6 3 0 0 3 3 3 0 ABC transporter cobW PF02492.14 CCV00411.1 - 0.078 12.4 1.2 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Spt5-NGN PF03439.8 CCV00412.1 - 1e-17 63.6 0.0 2.1e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 CCV00412.1 - 1.6e-17 62.4 20.3 9.1e-06 25.1 0.1 6.9 7 0 0 7 7 7 4 KOW motif Spt5_N PF11942.3 CCV00412.1 - 3.9e-12 46.6 14.3 3.9e-12 46.6 9.9 2.8 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 CCV00412.1 - 3.5e-06 27.4 63.0 4.2e-05 23.9 5.2 4.2 2 1 1 3 3 3 1 Spt5 C-terminal nonapeptide repeat binding Spt4 SDA1 PF05285.7 CCV00412.1 - 0.51 9.5 32.7 0.77 8.9 22.6 1.1 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 CCV00412.1 - 1.3 7.4 30.1 1.7 7.0 20.9 1.1 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 CCV00412.1 - 5.4 5.2 29.3 7.7 4.7 20.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PP2C PF00481.16 CCV00414.1 - 4e-34 118.1 0.0 7.3e-32 110.7 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C RRM_1 PF00076.17 CCV00415.1 - 2.6e-15 55.7 0.0 3.8e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCV00415.1 - 1.8e-08 34.2 0.0 1e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCV00415.1 - 1.4e-07 31.2 0.0 1.5e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CCV00415.1 - 0.058 12.9 0.1 0.5 9.9 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Zip PF02535.17 CCV00415.1 - 2 7.3 11.5 2.5 7.0 8.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 CCV00415.1 - 2.7 7.2 15.0 4.9 6.4 10.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region V-ATPase_C PF03223.10 CCV00416.1 - 5.9e-110 367.6 0.5 6.6e-110 367.5 0.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF2524 PF10732.4 CCV00416.1 - 0.063 13.3 1.2 0.44 10.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) DUF1524 PF07510.6 CCV00416.1 - 0.11 12.3 1.7 0.34 10.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1524) Hemerythrin PF01814.18 CCV00416.1 - 0.71 10.0 6.3 6.6 6.9 0.1 3.2 3 1 0 3 3 3 0 Hemerythrin HHE cation binding domain DHFR_1 PF00186.14 CCV00417.1 - 1.9e-22 79.5 0.0 2.2e-12 46.8 0.0 2.5 2 1 0 2 2 2 2 Dihydrofolate reductase PTS_2-RNA PF01885.11 CCV00417.1 - 5.4e-17 61.7 0.0 9.1e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family tRNA-synt_1c PF00749.16 CCV00418.1 - 1.6e-102 342.4 0.0 2.3e-102 341.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CCV00418.1 - 6.3e-34 117.1 0.1 1e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 CCV00418.1 - 1.3e-06 28.7 0.4 9.9e-06 25.9 0.1 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCV00418.1 - 3e-05 23.8 0.7 9.8e-05 22.1 0.5 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCV00418.1 - 0.00097 19.0 0.0 0.008 16.1 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MC1 PF05854.6 CCV00418.1 - 0.019 14.8 0.6 0.061 13.2 0.4 1.8 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 LSM PF01423.17 CCV00419.1 - 7.1e-18 63.9 0.2 1.1e-17 63.3 0.1 1.3 1 0 0 1 1 1 1 LSM domain adh_short PF00106.20 CCV00420.1 - 3.3e-64 215.8 6.8 5.7e-34 117.4 0.2 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCV00420.1 - 4.7e-33 114.3 2.9 2.9e-18 66.1 0.1 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 CCV00420.1 - 8.2e-31 105.9 0.0 1.8e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.1 CCV00420.1 - 2.5e-15 56.8 0.3 1.1e-06 28.5 0.1 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 CCV00420.1 - 3.3e-11 43.1 0.0 1.8e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.13 CCV00420.1 - 0.0061 16.2 3.8 0.31 10.6 0.3 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CCV00420.1 - 0.015 14.3 0.1 4.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.10 CCV00420.1 - 0.028 13.3 0.4 0.49 9.2 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF4161 PF13722.1 CCV00420.1 - 0.16 12.3 0.4 7.4 6.8 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) DUF3682 PF12446.3 CCV00420.1 - 4.7 7.5 6.2 0.84 9.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) NDUFA12 PF05071.11 CCV00421.1 - 3.7e-20 72.3 6.6 4.4e-20 72.0 4.6 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Polysacc_synt_4 PF04669.8 CCV00422.1 - 6.5e-20 71.2 1.2 3.8e-19 68.7 0.9 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis MutS_III PF05192.13 CCV00422.1 - 0.13 11.9 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 MutS domain III Asn_synthase PF00733.16 CCV00423.1 - 1.9e-50 171.7 0.2 3.2e-50 171.0 0.1 1.4 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CCV00423.1 - 0.00014 21.5 0.0 0.00043 19.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CCV00423.1 - 0.0074 16.2 0.0 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain HEV_ORF1 PF02444.11 CCV00424.1 - 0.1 12.7 1.1 0.19 11.9 0.2 1.8 1 1 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) MMR_HSR1 PF01926.18 CCV00425.1 - 2.2e-20 72.7 0.0 3.9e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 CCV00425.1 - 1.2e-18 67.2 1.8 2.3e-18 66.3 0.1 2.3 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE TrmE_N PF10396.4 CCV00425.1 - 2e-18 66.4 0.0 4.2e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus FeoB_N PF02421.13 CCV00425.1 - 1.9e-07 30.4 0.0 3.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCV00425.1 - 1.9e-05 24.5 0.0 0.00012 21.9 0.0 2.1 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 CCV00425.1 - 0.0001 22.7 0.0 0.00018 21.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 CCV00425.1 - 0.0062 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 CCV00425.1 - 0.021 13.9 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DAP3 PF10236.4 CCV00425.1 - 0.031 13.1 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.1 CCV00425.1 - 0.052 14.3 0.1 0.22 12.3 0.0 2.1 3 0 0 3 3 3 0 AAA domain DUF362 PF04015.7 CCV00425.1 - 0.075 12.5 0.0 0.56 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF362) AAA_28 PF13521.1 CCV00425.1 - 0.086 12.8 0.8 0.24 11.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain Ras PF00071.17 CCV00425.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Ras family Arch_ATPase PF01637.13 CCV00425.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 CCV00425.1 - 0.1 12.1 0.0 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CCV00425.1 - 0.14 12.3 0.1 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain FEZ PF07763.8 CCV00426.1 - 0.0024 17.6 0.0 0.006 16.3 0.0 1.6 2 0 0 2 2 2 1 FEZ-like protein Abhydrolase_6 PF12697.2 CCV00427.1 - 5.9e-29 101.5 2.1 8e-29 101.1 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCV00427.1 - 2.5e-11 43.5 0.0 4.3e-11 42.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCV00427.1 - 8.6e-09 35.2 0.0 2.4e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CCV00427.1 - 4.7e-08 33.5 0.1 7.9e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 CCV00427.1 - 0.0002 21.1 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 CCV00427.1 - 0.0016 17.8 0.0 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 CCV00427.1 - 0.0059 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.7 CCV00427.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1925 PF09094.6 CCV00427.1 - 0.023 14.6 0.1 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) Lipase_3 PF01764.20 CCV00427.1 - 0.029 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 CCV00427.1 - 0.054 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.2 CCV00427.1 - 0.084 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Aldo_ket_red PF00248.16 CCV00428.1 - 6.9e-69 231.7 0.0 8.3e-69 231.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 CCV00428.1 - 0.022 14.6 0.1 2.7 8.0 0.0 3.0 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Ribonuclease PF00545.15 CCV00429.1 - 2.2e-07 30.8 0.0 2.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 ribonuclease FTR1 PF03239.9 CCV00430.1 - 7.6e-55 186.0 6.2 5e-35 120.9 1.1 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family DUF3112 PF11309.3 CCV00430.1 - 0.00033 20.4 0.8 0.0016 18.2 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3112) Wzy_C PF04932.10 CCV00430.1 - 0.0017 18.1 6.6 0.013 15.2 0.1 3.0 3 0 0 3 3 3 2 O-Antigen ligase DUF3169 PF11368.3 CCV00430.1 - 0.01 15.0 5.2 0.25 10.4 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) Ldr_toxin PF13940.1 CCV00430.1 - 8.2 6.2 9.3 5.2 6.9 0.1 3.2 3 0 0 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system Cu-oxidase_2 PF07731.9 CCV00431.1 - 3.9e-37 126.8 2.7 6.2e-34 116.4 0.1 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 CCV00431.1 - 5e-35 120.7 0.0 9.6e-33 113.3 0.0 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 CCV00431.1 - 4.1e-28 97.4 0.5 9.3e-25 86.6 0.1 3.8 3 2 0 3 3 3 2 Multicopper oxidase Phosphoesterase PF04185.9 CCV00432.1 - 1.1e-83 281.5 0.7 1.6e-83 280.9 0.5 1.2 1 0 0 1 1 1 1 Phosphoesterase family Fascin PF06268.8 CCV00432.1 - 0.081 13.0 0.3 0.44 10.6 0.0 2.4 2 0 0 2 2 2 0 Fascin domain His_Phos_2 PF00328.17 CCV00433.1 - 7.8e-38 130.6 0.0 1e-37 130.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Thi4 PF01946.12 CCV00434.1 - 1.5e-87 292.5 0.0 1.8e-87 292.2 0.0 1.1 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CCV00434.1 - 2.1e-07 30.8 0.3 6.5e-07 29.2 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCV00434.1 - 1.4e-06 27.5 1.2 2.5e-06 26.6 0.7 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCV00434.1 - 5.5e-06 25.5 0.2 7.8e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CCV00434.1 - 3.7e-05 22.7 0.4 8.1e-05 21.6 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 CCV00434.1 - 5.8e-05 22.9 1.1 0.00071 19.3 0.1 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCV00434.1 - 0.00022 21.1 0.1 0.00041 20.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCV00434.1 - 0.00035 19.1 0.4 0.00051 18.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 CCV00434.1 - 0.0016 18.5 1.0 0.0083 16.2 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCV00434.1 - 0.04 12.7 0.0 0.15 10.9 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 CCV00434.1 - 0.14 10.7 0.2 0.21 10.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Transp_cyt_pur PF02133.10 CCV00435.1 - 2.2e-12 46.3 28.9 3.2e-12 45.7 20.0 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4181 PF13789.1 CCV00435.1 - 5.7 6.9 12.2 4.1 7.3 1.7 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4181) SH3_9 PF14604.1 CCV00437.1 - 2.4e-37 126.2 3.9 4e-15 55.1 0.2 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.23 CCV00437.1 - 4.1e-36 122.1 0.7 4.2e-14 51.6 0.1 4.1 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 CCV00437.1 - 2.7e-20 71.7 0.0 6.3e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 CCV00437.1 - 3.6e-18 64.8 0.0 3.6e-08 32.7 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 CCV00437.1 - 0.053 13.7 1.0 0.23 11.6 0.2 2.4 3 0 0 3 3 3 0 Bacterial SH3 domain Ribosomal_L28e PF01778.12 CCV00439.1 - 7.2e-29 100.5 2.8 7.5e-29 100.5 0.2 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 CCV00439.1 - 3.2e-20 72.1 29.7 1.1e-18 67.2 15.4 3.3 2 1 0 2 2 2 1 Mak16 protein C-terminal region PYC_OADA PF02436.13 CCV00439.1 - 0.082 12.3 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain Leucyl-specific PF14795.1 CCV00439.1 - 0.084 12.7 1.7 0.16 11.8 0.3 2.1 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain Nop14 PF04147.7 CCV00439.1 - 2.1 6.1 20.7 2.3 6.0 14.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CCV00439.1 - 7 4.5 13.0 12 3.8 9.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 CCV00440.1 - 4.8e-51 173.4 0.0 6e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCV00440.1 - 3.4e-47 160.7 0.0 4e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCV00440.1 - 0.00012 21.9 0.0 0.00052 19.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Nitroreductase PF00881.19 CCV00441.1 - 5.1e-27 94.6 0.1 5e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 Nitroreductase family PRP4 PF08799.6 CCV00442.1 - 3.2e-12 45.5 0.1 5.7e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like COX6B PF02297.12 CCV00443.1 - 9.1e-14 51.2 4.1 1.1e-13 50.9 2.9 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 CCV00443.1 - 0.11 12.4 0.6 0.22 11.4 0.4 1.6 1 1 0 1 1 1 0 CHCH domain Cation_ATPase_C PF00689.16 CCV00445.1 - 0.023 14.2 0.8 0.038 13.5 0.5 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus LEA_2 PF03168.8 CCV00445.1 - 0.034 14.5 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein Cpn60_TCP1 PF00118.19 CCV00446.1 - 5e-140 467.3 9.0 6.3e-140 467.0 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_14 PF13173.1 CCV00446.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain UFD1 PF03152.9 CCV00447.1 - 1.8e-28 98.9 0.0 6.3e-28 97.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Methyltransf_6 PF03737.10 CCV00448.1 - 1.8e-28 99.3 0.0 3.3e-24 85.5 0.0 2.1 2 0 0 2 2 2 2 Demethylmenaquinone methyltransferase DUF3808 PF10300.4 CCV00449.1 - 7.2e-84 282.0 1.2 1.2e-83 281.2 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.15 CCV00449.1 - 5.8e-36 123.3 0.0 1e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CCV00449.1 - 2.5e-14 53.4 0.0 8.8e-14 51.6 0.0 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCV00449.1 - 1.1e-10 41.5 0.0 2.8e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TPR_11 PF13414.1 CCV00449.1 - 2.4e-05 23.8 12.8 0.00052 19.6 0.1 4.8 3 1 1 4 4 4 2 TPR repeat TPR_8 PF13181.1 CCV00449.1 - 0.00087 18.9 0.2 15 5.6 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCV00449.1 - 0.0037 17.6 6.6 0.45 11.0 0.1 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCV00449.1 - 0.0061 16.4 9.6 0.28 11.1 0.3 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCV00449.1 - 0.008 16.8 11.3 0.14 12.8 0.6 3.9 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCV00449.1 - 0.079 12.6 11.6 2.9 7.6 0.3 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCV00449.1 - 0.086 12.7 20.0 0.078 12.9 0.2 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat CRA_rpt PF07046.6 CCV00449.1 - 0.16 11.9 4.2 0.53 10.3 2.9 1.9 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat TPR_4 PF07721.9 CCV00449.1 - 0.63 10.6 8.1 0.055 13.9 1.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 CCV00450.1 - 0.39 11.1 4.1 1.1 9.7 2.9 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCV00450.1 - 0.83 10.1 5.5 2.4 8.6 3.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger GAF PF01590.21 CCV00451.1 - 0.0073 16.4 0.1 0.01 15.9 0.1 1.5 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.1 CCV00451.1 - 0.029 14.8 0.3 0.4 11.1 0.0 2.4 2 1 0 2 2 2 0 GAF domain Abhydrolase_1 PF00561.15 CCV00452.1 - 3.3e-19 69.3 0.0 2.8e-16 59.7 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCV00452.1 - 3.7e-12 46.6 3.4 4.7e-11 43.0 2.4 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CCV00452.1 - 0.00041 19.8 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CCV00452.1 - 0.0058 16.4 0.0 0.097 12.4 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family tRNA-synt_His PF13393.1 CCV00453.1 - 1.2e-41 142.7 2.3 1.2e-36 126.4 0.0 2.7 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CCV00453.1 - 3.9e-19 68.8 0.0 5.6e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCV00453.1 - 4e-09 36.2 0.0 8.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 CCV00453.1 - 0.001 17.8 2.1 0.22 10.2 0.3 2.9 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 CCV00453.1 - 0.056 12.5 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Use1 PF09753.4 CCV00454.1 - 1.2e-07 31.4 0.0 2e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF2236 PF09995.4 CCV00454.1 - 0.004 16.4 6.0 0.02 14.1 1.3 2.4 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2236) Adenylsucc_synt PF00709.16 CCV00454.1 - 0.052 12.2 0.2 0.56 8.7 0.0 2.1 2 0 0 2 2 2 0 Adenylosuccinate synthetase Ribonuc_L-PSP PF01042.16 CCV00455.1 - 2.4e-37 127.3 0.4 4.2e-37 126.5 0.3 1.4 1 1 0 1 1 1 1 Endoribonuclease L-PSP SchA_CurD PF04486.7 CCV00455.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 SchA/CurD like domain RhoGEF PF00621.15 CCV00456.1 - 1.3e-13 51.2 0.0 4.7e-13 49.3 0.0 1.9 1 1 0 1 1 1 1 RhoGEF domain Ras PF00071.17 CCV00458.1 - 5.6e-59 198.1 0.1 7.3e-59 197.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCV00458.1 - 2.7e-20 73.0 0.0 4.1e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCV00458.1 - 5.5e-16 58.2 0.1 6.7e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCV00458.1 - 3.1e-07 29.9 0.0 2.1e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCV00458.1 - 3.7e-05 22.9 0.0 4.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCV00458.1 - 6.9e-05 22.7 0.0 0.00014 21.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCV00458.1 - 0.00013 21.2 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 CCV00458.1 - 0.091 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Seipin PF06775.9 CCV00459.1 - 1.1e-24 87.1 0.6 1.7e-24 86.4 0.0 1.6 2 0 0 2 2 2 1 Putative adipose-regulatory protein (Seipin) Claudin_2 PF13903.1 CCV00459.1 - 0.059 13.0 10.5 0.072 12.7 1.3 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2207 PF09972.4 CCV00459.1 - 6.3 5.2 5.7 1.3 7.5 0.6 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TAP42 PF04177.7 CCV00460.1 - 1.6e-55 188.4 0.0 1.9e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family DAGK_cat PF00781.19 CCV00461.1 - 1.8e-23 82.3 0.0 3.1e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 CCV00461.1 - 0.091 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Thioredoxin PF00085.15 CCV00462.1 - 8.7e-55 182.8 0.1 3.7e-28 97.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 CCV00462.1 - 4.5e-20 72.0 0.7 1.1e-19 70.8 0.1 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 CCV00462.1 - 1.9e-12 47.3 0.3 2.4e-05 24.5 0.0 3.2 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CCV00462.1 - 1.5e-10 40.9 0.1 0.00027 20.8 0.1 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 CCV00462.1 - 2.7e-10 40.2 0.4 0.0002 21.3 0.0 3.7 3 2 1 4 4 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CCV00462.1 - 2.6e-08 33.5 0.1 0.00095 18.8 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 CCV00462.1 - 1.9e-05 24.2 0.2 0.012 15.2 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.1 CCV00462.1 - 0.00037 20.3 0.1 0.012 15.3 0.1 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 CCV00462.1 - 0.00043 20.3 0.1 0.013 15.5 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_9 PF14595.1 CCV00462.1 - 0.016 14.8 0.1 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin DDE_Tnp_1_2 PF13586.1 CCV00462.1 - 0.038 14.1 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 0 Transposase DDE domain DUF1391 PF07151.7 CCV00462.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) HyaE PF07449.6 CCV00462.1 - 0.056 13.3 0.0 2.2 8.2 0.0 2.8 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Amidohydro_1 PF01979.15 CCV00463.1 - 6.6e-59 200.2 1.8 1.2e-58 199.4 0.9 1.6 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.15 CCV00463.1 - 1e-53 180.6 0.5 1.9e-53 179.7 0.3 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 CCV00463.1 - 1.8e-32 111.2 0.1 5e-32 109.8 0.1 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.15 CCV00463.1 - 2.9e-28 97.6 0.0 6.8e-28 96.4 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_5 PF13594.1 CCV00463.1 - 0.00024 20.8 2.6 0.00059 19.6 1.8 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CCV00463.1 - 0.00035 19.9 0.5 0.00086 18.6 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 CCV00463.1 - 0.0067 16.5 1.2 1.8 8.4 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase AhpC-TSA PF00578.16 CCV00464.1 - 1.4e-26 92.6 0.0 1.7e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCV00464.1 - 2.9e-16 59.3 0.0 3.9e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 CCV00464.1 - 0.026 14.4 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DEAD PF00270.24 CCV00465.1 - 4.8e-26 91.2 0.0 1.1e-25 90.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase UEV PF05743.8 CCV00465.1 - 1.3e-17 63.5 1.8 6e-16 58.2 0.3 2.4 1 1 1 2 2 2 2 UEV domain Helicase_C PF00271.26 CCV00465.1 - 5.3e-05 23.0 0.0 0.00024 20.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCV00465.1 - 0.00055 19.8 0.0 0.0012 18.6 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Vps23_core PF09454.5 CCV00465.1 - 0.0014 18.2 0.9 0.056 13.0 0.2 3.1 3 0 0 3 3 3 1 Vps23 core domain SNF2_N PF00176.18 CCV00465.1 - 0.0069 15.2 0.0 0.021 13.6 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CCV00465.1 - 0.032 14.3 1.4 0.34 11.0 0.1 3.2 2 1 0 2 2 2 0 AAA domain DHHA2 PF02833.9 CCV00466.1 - 4.2e-09 36.6 0.0 8.5e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 DHHA2 domain DHH PF01368.15 CCV00466.1 - 5e-08 32.6 0.0 7.6e-07 28.8 0.0 2.2 1 1 0 1 1 1 1 DHH family NTP_transf_3 PF12804.2 CCV00466.1 - 0.021 14.8 0.9 0.04 14.0 0.1 1.8 2 0 0 2 2 2 0 MobA-like NTP transferase domain Y_phosphatase2 PF03162.8 CCV00467.1 - 3.9e-40 136.9 0.0 4.4e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCV00467.1 - 3.6e-05 24.0 0.1 0.00046 20.4 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CCV00467.1 - 0.053 13.0 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF155 PF02582.9 CCV00468.1 - 2.3e-50 170.9 0.0 3.4e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 CCV00468.1 - 0.014 15.5 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Vps54 PF07928.7 CCV00469.1 - 6.3e-46 155.8 0.3 1.9e-45 154.3 0.2 1.9 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 CCV00469.1 - 3.9e-07 29.2 0.7 6.5e-07 28.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) RCC1 PF00415.13 CCV00470.1 - 2.4e-14 53.2 0.1 0.0026 17.9 0.0 5.4 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.1 CCV00470.1 - 1.4e-10 41.0 3.4 2e-07 31.0 0.8 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCV00470.1 - 2.1e-10 40.8 1.9 1.3e-09 38.3 0.8 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCV00470.1 - 1.5e-06 28.4 0.1 4.5e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CCV00470.1 - 1e-05 25.2 4.3 0.014 15.5 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 CCV00470.1 - 4e-05 23.2 1.9 0.0035 17.0 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeat PNMA PF14893.1 CCV00470.1 - 0.012 14.6 2.6 0.021 13.8 1.8 1.2 1 0 0 1 1 1 0 PNMA FliT PF05400.8 CCV00471.1 - 0.098 13.0 1.4 6.4 7.2 0.1 2.7 3 0 0 3 3 3 0 Flagellar protein FliT YchF-GTPase_C PF06071.8 CCV00472.1 - 5.8e-34 115.7 0.1 1.2e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CCV00472.1 - 3.2e-15 56.0 0.0 1.2e-14 54.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCV00472.1 - 1.7e-06 27.4 0.0 3.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.1 CCV00472.1 - 0.0019 18.5 1.2 2.9 8.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CCV00472.1 - 0.0037 16.9 0.4 2.4 7.8 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B BetaGal_dom3 PF13363.1 CCV00472.1 - 0.0039 16.5 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 AAA_17 PF13207.1 CCV00472.1 - 0.0084 16.9 0.7 0.08 13.7 0.5 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCV00472.1 - 0.028 14.3 0.0 0.17 11.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCV00472.1 - 0.26 11.5 1.1 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 ABC transporter RNase_HII PF01351.13 CCV00473.1 - 5.8e-43 146.8 0.0 1.2e-37 129.4 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease HII DNA_pol_A_exo1 PF01612.15 CCV00474.1 - 7.4e-34 116.7 0.2 1e-33 116.2 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 CCV00474.1 - 4.2e-10 39.2 0.2 8.8e-10 38.1 0.1 1.5 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.7 CCV00474.1 - 1.1e-09 38.4 0.0 2.1e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 PMC2NT (NUC016) domain Cellulase PF00150.13 CCV00475.1 - 6.2e-10 38.7 0.2 1.3e-09 37.6 0.1 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1469 PF07332.6 CCV00475.1 - 0.073 12.8 0.9 0.15 11.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) ETRAMP PF09716.5 CCV00475.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Harakiri PF15196.1 CCV00475.1 - 1.2 9.4 8.6 0.6 10.3 3.0 2.2 1 1 1 2 2 2 0 Activator of apoptosis harakiri DEAD PF00270.24 CCV00476.1 - 1.7e-43 148.0 0.3 8.1e-43 145.8 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCV00476.1 - 2.1e-28 97.9 0.4 6.1e-28 96.4 0.3 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CCV00476.1 - 0.0039 16.8 0.4 0.014 15.1 0.2 2.0 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 CCV00476.1 - 0.0096 15.7 0.6 0.023 14.5 0.1 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CCV00476.1 - 0.02 14.4 0.3 0.051 13.1 0.3 1.6 1 1 0 1 1 1 0 AAA domain DUF1253 PF06862.7 CCV00476.1 - 0.024 13.0 0.0 0.18 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_22 PF13401.1 CCV00476.1 - 0.13 12.3 0.3 0.52 10.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 CCV00477.1 - 2.5e-65 219.6 0.3 5.7e-65 218.5 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-met PF12874.2 CCV00477.1 - 4.4e-06 26.6 3.6 0.00016 21.7 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCV00477.1 - 5.2e-06 26.4 7.0 0.00019 21.4 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CCV00477.1 - 0.0067 16.5 0.0 6.7 6.8 0.0 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) SF3a60_bindingd PF12108.3 CCV00477.1 - 0.035 13.6 0.2 0.074 12.6 0.1 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain RPAP1_N PF08621.5 CCV00477.1 - 0.71 9.5 5.2 17 5.1 0.0 2.5 2 0 0 2 2 2 0 RPAP1-like, N-terminal Sugar_tr PF00083.19 CCV00479.1 - 3.5e-44 151.1 67.9 1.2e-19 70.3 19.7 4.1 2 2 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 CCV00479.1 - 2.4e-40 138.3 69.7 4.4e-11 42.1 12.1 4.2 2 2 2 4 4 4 4 Major Facilitator Superfamily MFS_2 PF13347.1 CCV00479.1 - 7.2e-08 31.2 52.3 0.0053 15.2 7.4 5.5 4 2 1 6 6 6 4 MFS/sugar transport protein Gal_mutarotas_2 PF13802.1 CCV00479.1 - 0.0032 17.2 0.2 3.3 7.6 0.0 2.6 2 0 0 2 2 2 2 Galactose mutarotase-like Coiled-coil_56 PF09813.4 CCV00479.1 - 0.1 12.6 1.0 17 5.4 0.1 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Gp5_OB PF06714.6 CCV00479.1 - 0.61 10.0 2.0 6.5 6.7 0.2 2.4 2 0 0 2 2 2 0 Gp5 N-terminal OB domain AAA_22 PF13401.1 CCV00480.1 - 7e-10 39.1 0.0 7.4e-09 35.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCV00480.1 - 5.9e-09 36.1 0.3 5.9e-09 36.1 0.2 3.6 3 1 1 4 4 4 2 AAA ATPase domain AAA PF00004.24 CCV00480.1 - 1.3e-06 28.6 0.0 3.7e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CCV00480.1 - 0.003 17.2 0.2 0.016 14.9 0.1 2.4 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CCV00480.1 - 0.0072 16.2 0.9 0.43 10.4 0.0 3.3 2 1 0 3 3 3 1 AAA domain NB-ARC PF00931.17 CCV00480.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 CCV00480.1 - 0.041 13.6 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CCV00480.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CCV00480.1 - 0.08 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 CCV00480.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain zf-CCHC PF00098.18 CCV00481.1 - 0.0002 21.1 42.6 0.00052 19.8 0.8 5.6 6 1 0 6 6 6 4 Zinc knuckle zf-CCHC_4 PF14392.1 CCV00481.1 - 0.11 12.1 31.4 0.31 10.7 0.4 5.5 4 1 1 5 5 5 0 Zinc knuckle Rad50_zn_hook PF04423.9 CCV00481.1 - 0.2 11.1 0.1 0.2 11.1 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif VESA1_N PF12785.2 CCV00481.1 - 3.1 6.6 11.8 4.2 6.2 8.2 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 TPP_enzyme_N PF02776.13 CCV00482.1 - 3.3e-35 121.1 0.2 1.1e-34 119.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCV00482.1 - 4.4e-22 78.3 0.0 9.9e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCV00482.1 - 1.2e-13 50.9 0.0 3.5e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CN_hydrolase PF00795.17 CCV00483.1 - 8.4e-17 61.1 0.0 1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LEA_2 PF03168.8 CCV00484.1 - 0.0014 18.9 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein YL1_C PF08265.6 CCV00485.1 - 3e-15 55.4 0.3 4.6e-15 54.8 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CM_2 PF01817.16 CCV00487.1 - 2.7e-05 24.1 0.0 0.00099 19.1 0.0 2.6 2 1 0 2 2 2 1 Chorismate mutase type II Kinesin PF00225.18 CCV00488.1 - 5.1e-113 377.1 0.3 1e-112 376.1 0.2 1.5 1 0 0 1 1 1 1 Kinesin motor domain Ribosomal_60s PF00428.14 CCV00488.1 - 0.011 16.1 2.1 0.011 16.1 1.5 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein FlaC_arch PF05377.6 CCV00488.1 - 3.6 7.5 11.9 0.77 9.6 0.2 5.0 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) OMPdecase PF00215.19 CCV00489.1 - 1.6e-70 237.0 0.0 2.5e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family HhH-GPD PF00730.20 CCV00489.1 - 2.8e-16 59.7 0.0 6.2e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CCV00489.1 - 1.8e-07 30.4 0.0 1.2e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 CCV00489.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Adeno_shaft PF00608.12 CCV00489.1 - 0.15 11.6 0.4 0.91 9.2 0.1 2.3 2 0 0 2 2 2 0 Adenoviral fibre protein (repeat/shaft region) LRR_4 PF12799.2 CCV00490.1 - 5.2e-20 70.6 0.0 3.7e-08 32.8 1.0 4.4 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCV00490.1 - 8.3e-19 67.1 21.8 2e-10 40.2 2.7 3.8 2 1 3 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 CCV00490.1 - 2.2e-10 39.0 6.8 2.6 8.3 0.2 7.2 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_7 PF13504.1 CCV00490.1 - 2.9e-08 32.6 14.6 0.58 10.5 0.4 8.0 8 0 0 8 8 8 3 Leucine rich repeat LRR_9 PF14580.1 CCV00490.1 - 4.7e-05 23.0 0.0 0.00058 19.4 0.0 2.3 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.1 CCV00490.1 - 0.0004 20.1 9.4 13 6.2 0.0 7.3 8 0 0 8 8 8 1 Leucine Rich repeat Alg6_Alg8 PF03155.10 CCV00491.1 - 1.5e-106 357.0 22.5 1.8e-106 356.8 15.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family SGS PF05002.10 CCV00492.1 - 8.5e-28 95.9 0.0 1.2e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 SGS domain Aconitase PF00330.15 CCV00493.1 - 2.7e-152 507.4 0.0 1.5e-151 505.0 0.0 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCV00493.1 - 2.8e-31 108.3 0.0 8.1e-31 106.8 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain MRP-L28 PF09812.4 CCV00493.1 - 3 7.6 8.8 1.4 8.7 2.6 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L28 ABC_membrane PF00664.18 CCV00494.1 - 1e-65 221.9 21.7 2.7e-37 128.6 6.9 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCV00494.1 - 8.6e-48 162.1 0.0 7e-30 104.1 0.0 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCV00494.1 - 0.0002 20.6 0.0 0.28 10.3 0.0 3.4 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCV00494.1 - 0.00067 19.1 0.2 1.6 8.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 CCV00494.1 - 0.0012 18.2 0.1 0.41 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CCV00494.1 - 0.0017 17.2 0.2 1.5 7.5 0.0 2.3 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 CCV00494.1 - 0.0037 17.1 0.3 2.4 8.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase IstB_IS21 PF01695.12 CCV00494.1 - 0.0045 16.4 0.2 4.7 6.5 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein DUF258 PF03193.11 CCV00494.1 - 0.0046 16.1 0.1 1.1 8.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCV00494.1 - 0.0068 16.4 9.3 0.019 14.9 0.8 3.0 3 0 0 3 3 3 1 AAA ATPase domain Miro PF08477.8 CCV00494.1 - 0.025 15.0 1.5 4.4 7.8 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein Dynamin_N PF00350.18 CCV00494.1 - 0.032 14.0 1.1 1.4 8.6 0.1 2.6 2 0 0 2 2 2 0 Dynamin family AAA_21 PF13304.1 CCV00494.1 - 0.078 12.9 0.2 8.1 6.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain 14-3-3 PF00244.15 CCV00494.1 - 0.19 10.7 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 14-3-3 protein DUF815 PF05673.8 CCV00494.1 - 0.19 10.6 0.4 10 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.12 CCV00494.1 - 0.58 9.9 0.9 3.3 7.4 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 E1-E2_ATPase PF00122.15 CCV00494.1 - 1.3 7.9 6.0 1.5 7.8 0.9 2.5 2 0 0 2 2 2 0 E1-E2 ATPase Gly_transf_sug PF04488.10 CCV00495.1 - 2.8e-20 72.6 0.0 4.9e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CCV00495.1 - 0.01 14.3 1.4 0.088 11.2 0.2 2.0 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 CCV00495.1 - 0.2 10.8 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein AAA PF00004.24 CCV00496.1 - 1.1e-57 193.8 0.0 1.2e-43 148.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 CCV00496.1 - 4e-18 65.2 0.3 8.5e-18 64.1 0.2 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 CCV00496.1 - 4.7e-12 46.2 12.5 1.3e-05 25.2 0.3 5.1 2 2 2 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 CCV00496.1 - 7.3e-12 46.1 0.4 2.3e-05 25.2 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 CCV00496.1 - 8.4e-09 35.1 12.6 0.007 15.7 2.7 5.2 3 2 1 4 4 4 2 AAA domain AAA_19 PF13245.1 CCV00496.1 - 1e-08 34.8 0.1 7.6e-05 22.3 0.0 3.3 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 CCV00496.1 - 4.9e-08 33.1 0.6 0.0091 16.1 0.0 3.9 2 2 1 3 3 3 2 AAA domain AAA_18 PF13238.1 CCV00496.1 - 4.9e-07 30.1 0.0 0.0045 17.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CCV00496.1 - 1e-06 28.6 0.0 0.048 13.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CCV00496.1 - 1.4e-06 27.9 0.1 0.0068 15.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.7 CCV00496.1 - 1.8e-06 27.2 0.0 0.0043 16.1 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CCV00496.1 - 6.3e-06 25.1 0.1 0.039 12.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 CCV00496.1 - 1e-05 25.4 0.0 0.052 13.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 CCV00496.1 - 2.1e-05 24.1 0.3 0.0034 17.0 0.0 2.8 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 CCV00496.1 - 2.2e-05 23.7 0.7 0.067 12.3 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCV00496.1 - 3.8e-05 23.4 0.1 0.61 9.8 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CCV00496.1 - 5.2e-05 22.4 0.0 0.061 12.4 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 CCV00496.1 - 6.5e-05 22.6 1.3 0.54 9.8 0.1 4.0 3 1 0 3 3 3 1 NACHT domain RNA_helicase PF00910.17 CCV00496.1 - 6.9e-05 22.9 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.9 CCV00496.1 - 0.00011 22.2 0.0 0.025 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) APS_kinase PF01583.15 CCV00496.1 - 0.00028 20.5 0.0 0.01 15.4 0.0 2.9 2 1 1 3 3 3 1 Adenylylsulphate kinase SKI PF01202.17 CCV00496.1 - 0.00052 19.9 0.7 0.43 10.4 0.0 2.7 3 0 0 3 3 2 1 Shikimate kinase AAA_28 PF13521.1 CCV00496.1 - 0.00054 19.9 0.5 0.52 10.2 0.2 2.7 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 CCV00496.1 - 0.00063 19.8 0.0 1.8 8.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 CCV00496.1 - 0.00064 20.0 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 CCV00496.1 - 0.0007 19.1 0.0 0.12 11.8 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_29 PF13555.1 CCV00496.1 - 0.00099 18.5 0.1 0.0091 15.5 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.17 CCV00496.1 - 0.0014 17.5 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Rad17 PF03215.10 CCV00496.1 - 0.0022 16.7 0.0 1.5 7.3 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 CCV00496.1 - 0.0032 17.1 3.2 0.49 9.9 0.2 2.5 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CCV00496.1 - 0.0033 17.1 0.1 0.24 11.0 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.1 CCV00496.1 - 0.0035 16.9 0.1 0.056 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCV00496.1 - 0.0062 16.2 0.0 4.5 6.9 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase T2SE PF00437.15 CCV00496.1 - 0.016 14.1 0.0 0.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Bac_DnaA PF00308.13 CCV00496.1 - 0.016 14.8 0.0 3.4 7.2 0.0 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein Cytidylate_kin2 PF13189.1 CCV00496.1 - 0.038 13.8 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family DUF815 PF05673.8 CCV00496.1 - 0.052 12.4 0.0 2.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KaiC PF06745.8 CCV00496.1 - 0.054 12.6 0.2 8.3 5.4 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.6 CCV00496.1 - 0.061 12.9 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CCV00496.1 - 0.063 12.7 0.2 0.34 10.3 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 CCV00496.1 - 0.067 13.5 0.4 0.24 11.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CCV00496.1 - 0.068 12.3 0.0 15 4.7 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 CCV00496.1 - 0.075 11.9 0.0 2.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 CCV00496.1 - 0.078 12.4 0.0 0.5 9.8 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PRK PF00485.13 CCV00496.1 - 0.13 11.7 0.0 0.54 9.7 0.0 2.0 2 0 0 2 2 1 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.14 CCV00496.1 - 0.21 11.0 0.6 8.3 5.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CCV00496.1 - 0.21 11.0 0.0 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ofd1_CTDD PF10637.4 CCV00497.1 - 1.9e-81 273.0 0.0 5.2e-76 255.2 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 CCV00497.1 - 6.5e-14 52.2 0.7 1.6e-13 50.9 0.5 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TRM PF02005.11 CCV00498.1 - 2.8e-102 342.4 0.0 2.5e-76 257.0 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 CCV00498.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L14 PF00238.14 CCV00499.1 - 1.4e-41 141.0 0.5 1.6e-41 140.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e His_Phos_1 PF00300.17 CCV00500.1 - 3.7e-14 53.1 0.1 1.3e-13 51.3 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Viral_env_E26 PF11050.3 CCV00500.1 - 0.065 12.4 0.3 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 Virus envelope protein E26 SlyX PF04102.7 CCV00500.1 - 0.89 9.9 4.3 1.9 8.8 3.0 1.6 1 0 0 1 1 1 0 SlyX CTDII PF01556.13 CCV00501.1 - 1.1e-23 82.9 1.4 1.2e-21 76.3 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 CCV00501.1 - 3.1e-22 78.0 0.5 6.3e-22 77.0 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CCV00501.1 - 3.9e-15 55.6 19.1 6.6e-15 54.9 13.2 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CCV00501.1 - 0.042 13.5 11.6 0.34 10.6 2.1 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 CCV00501.1 - 1.2 9.4 11.3 3.7 7.9 7.6 2.0 1 1 1 2 2 2 0 Cytochrome c3 Cytochrom_CIII PF02085.11 CCV00501.1 - 1.9 8.6 8.2 5.2 7.2 5.7 1.7 1 1 0 1 1 1 0 Class III cytochrome C family zinc-ribbons_6 PF07191.7 CCV00501.1 - 3.6 7.4 8.6 3.7 7.3 2.1 2.3 2 0 0 2 2 2 0 zinc-ribbons DUF21 PF01595.15 CCV00502.1 - 7.4e-34 116.6 1.1 1.1e-33 116.0 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CCV00502.1 - 0.00012 21.8 0.3 5.3 6.9 0.0 3.7 3 0 0 3 3 3 3 CBS domain CoA_trans PF01144.18 CCV00503.1 - 5.1e-195 643.6 9.7 4.5e-62 209.0 0.3 4.0 4 0 0 4 4 4 4 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CCV00503.1 - 0.00018 21.2 0.2 0.28 10.8 0.0 2.4 2 0 0 2 2 2 2 Acetyl-CoA hydrolase/transferase C-terminal domain DeoRC PF00455.17 CCV00503.1 - 0.0075 15.9 0.0 17 5.0 0.0 3.8 3 0 0 3 3 3 2 DeoR C terminal sensor domain RabGAP-TBC PF00566.13 CCV00504.1 - 4.9e-29 101.3 2.0 1.3e-27 96.7 0.2 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 CCV00504.1 - 0.018 14.3 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) Ribosomal_S21e PF01249.13 CCV00505.1 - 6.6e-33 112.5 0.1 7.3e-33 112.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e SpoA PF01052.15 CCV00505.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) UTP15_C PF09384.5 CCV00506.1 - 3.9e-43 146.6 0.0 5.7e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CCV00506.1 - 3.4e-31 105.9 1.3 2.3e-07 30.4 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 CCV00506.1 - 0.00098 17.3 0.4 2 6.4 0.0 3.3 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CCV00506.1 - 0.0032 15.8 0.0 0.007 14.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome D1 heme domain SKN1 PF03935.10 CCV00507.1 - 1.9e-176 587.1 6.2 2.3e-176 586.8 4.3 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Adaptin_N PF01602.15 CCV00507.1 - 5e-41 140.6 2.3 6.7e-41 140.1 1.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region UBN2 PF14223.1 CCV00507.1 - 0.038 13.7 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type HEAT_2 PF13646.1 CCV00507.1 - 0.058 13.6 0.1 0.88 9.8 0.2 2.2 1 1 1 2 2 2 0 HEAT repeats HLH PF00010.21 CCV00508.1 - 4.1e-05 23.1 0.0 0.00015 21.4 0.0 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PALP PF00291.20 CCV00509.1 - 9.8e-50 169.5 0.1 1.3e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.21 CCV00509.1 - 0.11 12.1 0.1 6.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Zinc-binding dehydrogenase zf-RING_4 PF14570.1 CCV00511.1 - 2e-22 78.4 11.8 3.4e-22 77.7 8.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CCV00511.1 - 1.6e-06 27.6 9.3 2.8e-06 26.8 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCV00511.1 - 0.00016 21.4 11.3 0.00029 20.5 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCV00511.1 - 0.00064 19.6 12.5 0.0012 18.7 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CCV00511.1 - 0.0049 16.5 5.4 0.0085 15.8 3.7 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-C3HC4 PF00097.20 CCV00511.1 - 0.012 15.2 11.9 0.024 14.3 8.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 CCV00511.1 - 0.029 14.0 5.7 0.029 14.0 3.9 1.6 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.7 CCV00511.1 - 0.034 13.3 1.0 0.034 13.3 0.7 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Prok-RING_4 PF14447.1 CCV00511.1 - 0.19 11.2 9.2 0.35 10.4 3.5 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.7 CCV00511.1 - 0.26 11.4 3.2 1.9 8.6 0.7 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.1 CCV00511.1 - 0.29 10.9 10.0 0.69 9.6 7.0 1.7 1 1 0 1 1 1 0 zinc-RING finger domain DUF1272 PF06906.6 CCV00511.1 - 1.4 8.8 6.9 2.6 7.9 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DAO PF01266.19 CCV00514.1 - 2.6e-43 148.3 9.6 3.5e-43 147.8 6.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCV00514.1 - 1.3e-06 28.3 0.1 5e-06 26.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCV00514.1 - 0.0034 17.4 0.0 0.027 14.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 CCV00514.1 - 0.004 15.4 0.0 0.0061 14.7 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.7 CCV00514.1 - 0.06 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 CCV00514.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Snf7 PF03357.16 CCV00515.1 - 1.6e-39 134.9 13.3 1.6e-39 134.9 9.2 1.6 1 1 1 2 2 2 1 Snf7 Ribosomal_60s PF00428.14 CCV00515.1 - 0.024 15.0 4.5 0.62 10.5 0.5 2.7 2 1 1 3 3 3 0 60s Acidic ribosomal protein Resolvase PF00239.16 CCV00515.1 - 0.11 12.3 3.5 0.15 11.9 2.0 1.5 1 1 0 1 1 1 0 Resolvase, N terminal domain Atg14 PF10186.4 CCV00515.1 - 0.44 9.4 7.5 0.86 8.4 5.2 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 BRE1 PF08647.6 CCV00515.1 - 1.3 9.0 8.0 0.14 12.1 2.1 2.1 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.1 CCV00515.1 - 2.3 7.0 10.4 1.1 8.1 5.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TEX13 PF15186.1 CCV00515.1 - 3.3 7.2 7.8 0.73 9.3 3.1 1.7 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family MFS_1 PF07690.11 CCV00516.1 - 3.5e-64 216.7 90.2 2.9e-32 111.7 27.3 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2721 PF11026.3 CCV00516.1 - 0.014 15.0 0.6 0.014 15.0 0.4 6.1 9 0 0 9 9 9 0 Protein of unknown function (DUF2721) TIM21 PF08294.6 CCV00516.1 - 0.061 12.9 0.1 0.93 9.1 0.0 2.3 2 0 0 2 2 2 0 TIM21 Baculo_11_kDa PF06143.6 CCV00516.1 - 0.12 11.7 1.0 7.5 5.9 0.0 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family Mito_carr PF00153.22 CCV00520.1 - 1.2e-64 213.9 4.7 1.8e-23 82.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.26 CCV00521.1 - 1.6e-16 59.7 0.2 2.7e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain MerR_1 PF13411.1 CCV00521.1 - 0.034 13.9 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein DUF1977 PF09320.6 CCV00522.1 - 2.6e-09 37.2 4.3 2.8e-08 33.9 3.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1977) TFIIS_C PF01096.13 CCV00523.1 - 3.6e-16 58.4 0.5 3.6e-16 58.4 0.3 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CCV00523.1 - 5.4e-06 25.9 6.4 0.008 15.8 0.1 3.1 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.2 CCV00523.1 - 6.3e-05 22.7 6.9 0.036 13.8 0.1 3.0 2 1 1 3 3 3 2 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 CCV00523.1 - 0.0023 17.5 5.5 0.19 11.3 0.1 2.7 2 1 0 2 2 2 1 Putative transposase DNA-binding domain Terminase_GpA PF05876.7 CCV00523.1 - 0.0036 15.7 0.5 0.0036 15.7 0.3 1.2 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Lar_restr_allev PF14354.1 CCV00523.1 - 0.0044 17.2 0.7 0.0044 17.2 0.5 2.7 2 1 0 2 2 2 1 Restriction alleviation protein Lar Prok-RING_1 PF14446.1 CCV00523.1 - 0.0058 16.3 9.1 0.057 13.1 0.6 3.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.1 CCV00523.1 - 0.007 15.8 10.4 0.37 10.3 0.2 3.8 4 0 0 4 4 4 1 zinc-ribbon domain HypA PF01155.14 CCV00523.1 - 0.01 15.5 4.1 2.6 7.7 0.9 2.8 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-DNA_Pol PF08996.5 CCV00523.1 - 0.014 14.7 1.7 0.056 12.8 0.5 2.0 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger TF_Zn_Ribbon PF08271.7 CCV00523.1 - 0.016 14.5 12.1 0.29 10.4 1.5 3.5 2 2 0 2 2 2 0 TFIIB zinc-binding zf-RING_3 PF14369.1 CCV00523.1 - 0.031 14.2 3.2 6.2 6.9 0.1 3.3 3 0 0 3 3 3 0 zinc-finger DNA_RNApol_7kD PF03604.8 CCV00523.1 - 0.038 13.4 0.3 0.038 13.4 0.2 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.5 CCV00523.1 - 0.039 13.4 8.3 0.12 11.8 0.1 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-TFIIB PF13453.1 CCV00523.1 - 0.052 12.7 1.5 0.052 12.7 1.0 2.2 3 1 0 3 3 2 0 Transcription factor zinc-finger DUF1451 PF07295.6 CCV00523.1 - 0.073 12.8 3.3 0.97 9.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1451) IBR PF01485.16 CCV00523.1 - 0.087 12.7 4.4 5.7 6.8 1.1 2.6 2 1 0 2 2 2 0 IBR domain zf-H2C2_2 PF13465.1 CCV00523.1 - 0.12 12.7 1.5 0.12 12.7 1.1 2.9 3 1 1 4 4 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 CCV00523.1 - 0.14 12.1 14.8 4.3 7.3 0.6 3.7 2 2 1 4 4 4 0 Zinc ribbon domain DUF2387 PF09526.5 CCV00523.1 - 0.23 11.4 5.0 1.6 8.7 0.2 2.8 2 1 1 3 3 3 0 Probable metal-binding protein (DUF2387) Ribosomal_S27e PF01667.12 CCV00523.1 - 0.24 10.9 8.9 1.5 8.4 0.0 3.8 3 1 1 4 4 4 0 Ribosomal protein S27 zf-ribbon_3 PF13248.1 CCV00523.1 - 0.27 10.4 16.9 1.6 8.0 0.3 3.8 3 1 0 3 3 3 0 zinc-ribbon domain zf-ISL3 PF14690.1 CCV00523.1 - 0.41 10.7 6.1 20 5.3 0.2 3.7 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_5 PF13719.1 CCV00523.1 - 0.63 9.6 11.3 6.8 6.3 0.4 4.0 3 1 1 4 4 4 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 CCV00523.1 - 0.78 9.3 9.4 13 5.3 0.1 3.9 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain FYDLN_acid PF09538.5 CCV00523.1 - 0.81 10.2 3.4 4.3 7.9 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_4 PF13717.1 CCV00523.1 - 0.86 9.3 11.8 8.8 6.1 0.4 4.0 3 1 1 4 4 4 0 zinc-ribbon domain Nop10p PF04135.7 CCV00523.1 - 0.89 9.3 3.5 1.2 8.9 0.1 2.7 3 0 0 3 3 2 0 Nucleolar RNA-binding protein, Nop10p family Nudix_N_2 PF14803.1 CCV00523.1 - 1.9 8.2 11.3 15 5.4 2.2 3.9 3 1 0 3 3 3 0 Nudix N-terminal DUF2072 PF09845.4 CCV00523.1 - 2.4 8.1 7.3 14 5.5 0.1 3.1 1 1 2 3 3 3 0 Zn-ribbon containing protein (DUF2072) Baculo_LEF5_C PF11792.3 CCV00523.1 - 2.9 7.3 6.3 0.24 10.7 0.1 2.5 3 1 0 3 3 2 0 Baculoviridae late expression factor 5 C-terminal domain GFA PF04828.9 CCV00523.1 - 3.8 7.5 7.5 6 6.8 0.2 2.9 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme CpXC PF14353.1 CCV00523.1 - 4 7.4 8.3 20 5.1 1.3 3.3 2 1 2 4 4 3 0 CpXC protein PHD PF00628.24 CCV00523.1 - 6.4 6.5 6.7 1.8 8.3 0.2 2.6 2 1 0 2 2 2 0 PHD-finger DUF678 PF05077.7 CCV00523.1 - 6.8 6.7 10.8 1.7 8.6 0.3 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF678) zf-AN1 PF01428.11 CCV00523.1 - 7.3 6.5 6.5 25 4.8 0.1 3.2 3 1 0 3 3 3 0 AN1-like Zinc finger C1_4 PF07975.7 CCV00523.1 - 7.5 6.6 8.0 9.5 6.3 1.7 2.9 2 1 1 3 3 3 0 TFIIH C1-like domain zf-CSL PF05207.8 CCV00523.1 - 7.5 6.1 12.2 1.1 8.7 0.4 3.1 2 2 0 3 3 3 0 CSL zinc finger Lactamase_B PF00753.22 CCV00524.1 - 1.7e-13 50.6 3.0 1.8e-08 34.2 0.6 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCV00524.1 - 0.011 15.3 0.3 0.015 14.8 0.2 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain adh_short PF00106.20 CCV00525.1 - 7.4e-27 94.2 1.2 1.1e-26 93.7 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCV00525.1 - 4.4e-26 92.1 0.0 5.9e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCV00525.1 - 2.3e-12 46.9 0.6 4e-12 46.1 0.4 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.22 CCV00525.1 - 0.0015 18.8 0.0 0.0037 17.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3Beta_HSD PF01073.14 CCV00525.1 - 0.0021 16.7 0.1 0.0031 16.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.10 CCV00525.1 - 0.037 13.8 0.5 0.11 12.3 0.2 2.0 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Vmethyltransf PF01660.12 CCV00525.1 - 0.043 12.4 0.0 0.066 11.8 0.0 1.2 1 0 0 1 1 1 0 Viral methyltransferase 3HCDH_N PF02737.13 CCV00525.1 - 0.18 11.4 1.7 0.19 11.3 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.27 CCV00526.1 - 3.5e-43 143.9 21.8 2.4e-09 36.7 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Hira PF07569.6 CCV00526.1 - 9.8e-15 54.3 0.0 3.7e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 TUP1-like enhancer of split HIRA_B PF09453.5 CCV00526.1 - 0.16 11.5 3.0 0.4 10.2 2.1 1.7 1 0 0 1 1 1 0 HIRA B motif Selenoprotein_S PF06936.6 CCV00527.1 - 3.8 6.9 9.4 7.8 5.9 6.5 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF2404 PF10296.4 CCV00528.1 - 0.00011 22.2 0.0 0.00035 20.6 0.0 1.7 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) RabGAP-TBC PF00566.13 CCV00529.1 - 5.5e-38 130.5 0.0 9.6e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Elongin_A PF06881.6 CCV00529.1 - 7.8e-28 97.0 0.1 1.6e-27 95.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Cyclin PF08613.6 CCV00530.1 - 4e-11 43.5 0.0 6.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin CorA PF01544.13 CCV00531.1 - 7e-11 41.6 4.9 1.1e-10 41.1 3.4 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pox_F11 PF04943.7 CCV00531.1 - 0.13 11.1 2.5 0.19 10.5 1.8 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein FlaC_arch PF05377.6 CCV00531.1 - 0.29 11.0 6.2 1.2 9.0 1.9 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Transaldolase PF00923.14 CCV00532.1 - 1e-93 313.6 0.0 1.2e-93 313.4 0.0 1.0 1 0 0 1 1 1 1 Transaldolase XS PF03468.9 CCV00532.1 - 0.15 12.0 0.0 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 XS domain GNAT_acetyltr_2 PF13718.1 CCV00533.1 - 4.3e-75 251.3 0.0 6.4e-75 250.7 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CCV00533.1 - 3.1e-65 219.1 0.0 1.2e-64 217.1 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 CCV00533.1 - 7.4e-35 118.5 0.0 3.7e-34 116.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CCV00533.1 - 6.8e-28 96.7 0.2 2.1e-27 95.1 0.1 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 CCV00533.1 - 0.00054 20.0 0.0 0.0019 18.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCV00533.1 - 0.0034 17.3 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PRMT5 PF05185.11 CCV00534.1 - 0.0026 16.7 0.0 0.0039 16.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Bromodomain PF00439.20 CCV00535.1 - 5.4e-22 77.5 0.1 9.2e-22 76.7 0.1 1.3 1 0 0 1 1 1 1 Bromodomain Epsilon_antitox PF08998.6 CCV00535.1 - 0.057 13.3 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial epsilon antitoxin SMN PF06003.7 CCV00535.1 - 0.18 10.8 3.5 0.29 10.2 2.4 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ribosomal_60s PF00428.14 CCV00535.1 - 7.8 6.9 10.4 1.8 9.0 1.3 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Complex1_49kDa PF00346.14 CCV00536.1 - 6.2e-123 409.1 0.0 8.4e-123 408.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit COPIIcoated_ERV PF07970.7 CCV00537.1 - 1.6e-65 220.8 0.1 2.4e-65 220.2 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCV00537.1 - 2.1e-31 107.7 0.0 4.5e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Uds1 PF15456.1 CCV00538.1 - 2.4e-09 37.2 10.5 2.4e-09 37.2 7.3 6.3 5 2 1 6 6 6 1 Up-regulated During Septation IncA PF04156.9 CCV00538.1 - 0.27 10.7 0.0 0.27 10.7 0.0 7.1 5 2 1 6 6 6 0 IncA protein CAP_GLY PF01302.20 CCV00539.1 - 2e-23 81.8 0.4 3.2e-23 81.1 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 CCV00539.1 - 4.7e-08 33.1 0.0 7.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain DSPc PF00782.15 CCV00540.1 - 5.5e-26 90.7 0.0 7.5e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF442 PF04273.8 CCV00540.1 - 0.00015 21.5 0.1 0.00066 19.5 0.0 2.0 2 0 0 2 2 2 1 Putative phosphatase (DUF442) Rhodanese PF00581.15 CCV00540.1 - 0.012 15.9 0.0 0.22 11.8 0.0 2.5 2 0 0 2 2 2 0 Rhodanese-like domain Y_phosphatase3 PF13350.1 CCV00540.1 - 0.054 13.7 0.4 0.86 9.8 0.1 2.1 1 1 1 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 CCV00540.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CUE PF02845.11 CCV00541.1 - 1.6e-09 37.0 0.0 2.5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain zf-C2H2 PF00096.21 CCV00542.1 - 5.6e-08 32.6 16.6 7.1e-05 22.9 0.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCV00542.1 - 1.3e-07 31.5 12.3 1.6e-07 31.2 2.6 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCV00542.1 - 3.5e-06 26.9 11.4 0.00096 19.3 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCV00542.1 - 0.51 10.3 3.8 0.19 11.6 0.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCV00542.1 - 2.1 8.6 9.8 5.5 7.2 2.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding UCH PF00443.24 CCV00543.1 - 2.8e-44 151.2 0.0 3.7e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCV00543.1 - 1.2e-18 67.5 0.0 2.8e-18 66.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CCV00543.1 - 3.3e-09 35.9 0.0 8.3e-09 34.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DALR_1 PF05746.10 CCV00543.1 - 0.059 13.3 0.1 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 DALR anticodon binding domain Noc2 PF03715.8 CCV00544.1 - 8.4e-101 336.7 0.0 1.2e-100 336.3 0.0 1.2 1 0 0 1 1 1 1 Noc2p family SecM PF06558.7 CCV00544.1 - 0.045 13.4 0.2 0.13 11.9 0.2 1.7 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) Nif11 PF07862.6 CCV00544.1 - 1.2 9.1 9.0 0.56 10.1 0.9 3.7 4 1 0 4 4 4 0 Nitrogen fixation protein of unknown function WD40 PF00400.27 CCV00545.1 - 2.4e-15 55.7 0.1 6.9e-05 22.5 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat SH3_9 PF14604.1 CCV00546.1 - 5.3e-33 112.3 2.7 1.7e-16 59.5 0.1 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CCV00546.1 - 6.4e-27 92.6 2.5 1.1e-12 47.1 0.1 2.1 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 CCV00546.1 - 2.2e-16 59.0 0.0 7.6e-08 31.7 0.0 2.1 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 CCV00547.1 - 6.3e-13 48.7 0.0 8.2e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF605 PF04652.11 CCV00547.1 - 1.1 8.5 16.3 1.3 8.3 11.3 1.1 1 0 0 1 1 1 0 Vta1 like DUF1620 PF07774.8 CCV00548.1 - 1e-41 142.5 0.0 1.4e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 CCV00548.1 - 0.00033 20.1 1.5 0.074 12.4 0.0 3.4 4 0 0 4 4 4 2 PQQ-like domain PQQ PF01011.16 CCV00548.1 - 0.09 12.3 0.0 16 5.2 0.0 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat DUF1752 PF08550.5 CCV00549.1 - 2.2e-11 43.1 3.9 3.9e-11 42.3 2.7 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RNA_pol_A_bac PF01000.21 CCV00550.1 - 1.1e-29 102.8 0.0 2.3e-29 101.8 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CCV00550.1 - 4.6e-05 22.4 0.0 5.9e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF883 PF05957.8 CCV00551.1 - 0.0002 21.6 13.5 0.13 12.6 2.1 3.8 1 1 0 2 2 2 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 CCV00551.1 - 0.0048 16.4 4.3 0.079 12.4 2.7 2.1 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain MT0933_antitox PF14013.1 CCV00551.1 - 0.0074 16.3 1.8 0.0074 16.3 1.3 3.2 3 1 0 3 3 2 1 MT0933-like antitoxin protein Apo-CIII PF05778.7 CCV00551.1 - 0.011 15.0 10.1 0.65 9.4 0.3 3.9 1 1 2 4 4 4 0 Apolipoprotein CIII (Apo-CIII) YtxH PF12732.2 CCV00551.1 - 0.023 15.0 14.4 2 8.8 1.4 3.7 1 1 1 2 2 2 0 YtxH-like protein Tape_meas_lam_C PF09718.5 CCV00551.1 - 0.047 13.6 16.1 0.13 12.1 1.0 4.1 1 1 4 5 5 5 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) RRF PF01765.14 CCV00551.1 - 0.05 13.0 2.0 1.2 8.5 0.1 2.2 1 1 1 2 2 2 0 Ribosome recycling factor Phasin_2 PF09361.5 CCV00551.1 - 0.12 12.4 16.1 0.18 11.8 6.5 3.0 1 1 2 3 3 3 0 Phasin protein ApoO PF09769.4 CCV00551.1 - 0.12 12.0 4.8 35 4.0 0.2 3.4 1 1 1 3 3 3 0 Apolipoprotein O DUF2580 PF10824.3 CCV00551.1 - 0.18 12.1 15.3 0.37 11.1 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2580) DUF745 PF05335.8 CCV00551.1 - 0.2 11.1 25.3 0.016 14.7 8.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Mnd1 PF03962.10 CCV00551.1 - 0.2 11.2 3.5 0.33 10.6 1.9 1.6 1 1 1 2 2 2 0 Mnd1 family Chlorosome_CsmC PF11098.3 CCV00551.1 - 0.22 11.2 8.2 0.36 10.5 0.3 2.3 2 0 0 2 2 2 0 Chlorosome envelope protein C Phasin PF05597.6 CCV00551.1 - 0.22 11.2 9.6 5.3 6.8 3.7 2.9 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ATP-synt_B PF00430.13 CCV00551.1 - 0.91 9.3 18.4 3.9 7.2 5.9 3.0 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) TP53IP5 PF15331.1 CCV00551.1 - 3.6 7.4 9.4 0.3 10.9 1.9 1.8 1 1 1 2 2 2 0 Cellular tumour antigen p53-inducible 5 Peptidase_S64 PF08192.6 CCV00551.1 - 7.8 4.6 12.7 8.2 4.6 8.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Vps53_N PF04100.7 CCV00551.1 - 8 5.1 8.0 5 5.7 1.5 2.1 1 1 2 3 3 3 0 Vps53-like, N-terminal DUF2470 PF10615.4 CCV00553.1 - 2.2e-17 63.0 0.1 3e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) YqzE PF14038.1 CCV00553.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 YqzE-like protein DUF221 PF02714.10 CCV00554.1 - 7.2e-83 278.1 15.5 7.2e-83 278.1 10.7 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCV00554.1 - 3.5e-33 114.3 3.7 3.5e-33 114.3 2.6 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CCV00554.1 - 1.4e-21 76.7 0.7 2.9e-21 75.7 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 CCV00554.1 - 2.4e-13 49.7 0.5 6.5e-13 48.3 0.3 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein Rifin_STEVOR PF02009.11 CCV00554.1 - 0.037 13.6 0.1 0.037 13.6 0.1 2.2 3 0 0 3 3 3 0 Rifin/stevor family DUF21 PF01595.15 CCV00555.1 - 4.7e-36 123.7 0.4 6.4e-36 123.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CCV00555.1 - 5.1e-05 22.9 2.6 0.025 14.3 0.0 3.3 4 0 0 4 4 4 2 CBS domain TGS PF02824.16 CCV00556.1 - 1.4e-20 72.8 0.0 2.6e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CCV00556.1 - 9.6e-18 64.2 0.1 2.3e-17 63.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCV00556.1 - 4.3e-09 35.8 0.2 1.3e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCV00556.1 - 0.017 14.9 0.4 0.52 10.1 0.0 2.2 1 1 1 2 2 2 0 Dynamin family Miro PF08477.8 CCV00556.1 - 0.024 15.1 0.0 0.091 13.2 0.0 1.9 1 1 1 2 2 2 0 Miro-like protein ArgK PF03308.11 CCV00556.1 - 0.048 12.4 0.7 0.11 11.1 0.5 1.6 1 0 0 1 1 1 0 ArgK protein GTP_EFTU PF00009.22 CCV00556.1 - 0.051 12.9 0.2 6.4 6.1 0.0 2.7 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain DUF211 PF02680.9 CCV00556.1 - 0.11 12.2 0.3 0.26 11.1 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 ATP_bind_3 PF01171.15 CCV00557.1 - 1.2e-12 47.6 0.0 3e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 PP-loop family Asn_synthase PF00733.16 CCV00557.1 - 0.053 13.0 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.11 CCV00557.1 - 0.11 11.0 0.2 0.6 8.5 0.1 1.9 1 1 0 1 1 1 0 tRNA methyl transferase TF_Zn_Ribbon PF08271.7 CCV00557.1 - 6 6.2 14.3 0.058 12.7 0.7 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding TPR_11 PF13414.1 CCV00558.1 - 9.4e-06 25.1 4.5 0.11 12.1 0.1 3.7 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CCV00558.1 - 0.0097 15.7 14.8 0.11 12.4 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCV00558.1 - 0.033 14.1 17.1 0.038 13.9 0.0 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCV00558.1 - 0.18 11.6 3.7 9 6.3 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCV00558.1 - 1.2 8.8 4.0 3.4 7.4 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Cation_efflux PF01545.16 CCV00559.1 - 7.9e-32 110.4 8.3 1.1e-31 109.9 5.8 1.2 1 0 0 1 1 1 1 Cation efflux family Ycf66_N PF07444.6 CCV00559.1 - 0.076 12.7 0.3 0.076 12.7 0.2 2.3 3 0 0 3 3 3 0 Ycf66 protein N-terminus EphA2_TM PF14575.1 CCV00559.1 - 0.27 11.6 1.0 0.86 10.0 0.1 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Iso_dh PF00180.15 CCV00560.1 - 2.5e-119 398.3 0.0 3e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Acatn PF13000.2 CCV00561.1 - 1.1e-133 446.6 19.8 7.9e-64 216.1 4.5 3.7 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 4HBT PF03061.17 CCV00562.1 - 3.7e-08 33.3 0.0 7.8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily MFS_1 PF07690.11 CCV00563.1 - 1.9e-57 194.6 40.9 8e-30 103.7 10.2 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily tRNA_bind_2 PF13725.1 CCV00563.1 - 2.3e-07 30.8 0.3 0.0031 17.5 0.0 2.5 2 0 0 2 2 2 2 Possible tRNA binding domain DUF3481 PF11980.3 CCV00563.1 - 0.00071 19.3 0.0 0.77 9.6 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF3481) DUF2625 PF10946.3 CCV00563.1 - 0.021 13.7 0.6 2.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF2625 DUF912 PF06024.7 CCV00563.1 - 0.13 12.3 0.0 1e+02 3.0 0.0 3.9 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DGCR6 PF07324.6 CCV00563.1 - 0.2 11.1 0.1 17 4.8 0.0 2.4 2 0 0 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein UCH PF00443.24 CCV00564.1 - 9.1e-34 116.7 0.0 1.2e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCV00564.1 - 1.4e-11 44.3 0.9 2.6e-11 43.4 0.6 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 CCV00564.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Peptidase_M18 PF02127.10 CCV00565.1 - 3e-144 480.7 0.0 3.5e-144 480.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CCV00565.1 - 0.018 13.8 0.0 0.33 9.6 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase GIDA PF01134.17 CCV00567.1 - 5.6e-125 417.2 0.0 1.4e-124 415.9 0.0 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 CCV00567.1 - 3e-15 56.0 0.0 1e-14 54.3 0.0 2.0 1 0 0 1 1 1 1 GidA associated domain 3 FAD_oxidored PF12831.2 CCV00567.1 - 3.5e-07 29.6 3.6 1.3e-06 27.7 2.6 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCV00567.1 - 4.2e-06 26.7 0.4 8.4e-06 25.8 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCV00567.1 - 0.00019 20.4 4.5 0.054 12.3 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCV00567.1 - 0.0045 15.8 3.7 0.0045 15.8 2.6 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 CCV00567.1 - 0.015 15.7 0.3 0.039 14.3 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCV00567.1 - 0.022 13.2 1.2 0.042 12.3 0.8 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.1 CCV00567.1 - 0.034 14.1 1.9 0.9 9.6 0.9 3.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCV00567.1 - 0.048 13.7 0.8 0.19 11.7 0.5 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CCV00567.1 - 0.06 12.9 1.5 0.1 12.1 1.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_M28 PF04389.12 CCV00568.1 - 5.8e-32 110.8 0.0 9.7e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CCV00568.1 - 0.002 17.6 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Daxx PF03344.10 CCV00569.1 - 0.035 12.5 17.5 0.043 12.3 12.2 1.1 1 0 0 1 1 1 0 Daxx Family COPI_C PF06957.6 CCV00569.1 - 0.049 12.1 6.9 0.07 11.6 4.8 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus PrmA PF06325.8 CCV00570.1 - 2e-12 46.8 0.0 3.3e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 CCV00570.1 - 2.6e-12 46.5 0.0 4.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCV00570.1 - 1.3e-09 38.0 0.7 3.3e-09 36.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCV00570.1 - 4.7e-09 36.8 0.0 1.1e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCV00570.1 - 1.8e-07 31.5 0.1 9.3e-07 29.2 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain MTS PF05175.9 CCV00570.1 - 3e-07 29.9 0.0 5.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CCV00570.1 - 1.5e-06 28.0 0.0 3.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CCV00570.1 - 1.1e-05 26.1 0.2 0.00059 20.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCV00570.1 - 1.2e-05 25.5 0.0 3.6e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCV00570.1 - 2.4e-05 23.5 0.0 4.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CCV00570.1 - 3.4e-05 24.2 0.0 0.00011 22.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PRMT5 PF05185.11 CCV00570.1 - 7.6e-05 21.7 0.0 0.0002 20.4 0.0 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.4 CCV00570.1 - 0.0012 18.2 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Cons_hypoth95 PF03602.10 CCV00570.1 - 0.0041 16.5 0.0 0.008 15.5 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.14 CCV00570.1 - 0.0084 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 CCV00570.1 - 0.0085 14.8 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.9 CCV00570.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 CCV00570.1 - 0.11 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain eIF2A PF08662.6 CCV00571.1 - 2.2e-81 272.2 0.0 1e-76 257.0 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CCV00571.1 - 0.0014 18.4 0.0 4.5 7.2 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.1 CCV00571.1 - 0.0087 16.1 2.0 0.0087 16.1 1.4 2.2 3 0 0 3 3 3 1 Carnitine deficiency-associated protein 3 Glyco_hydro_31 PF01055.21 CCV00572.1 - 2.9e-133 444.9 0.5 3.9e-133 444.5 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CCV00572.1 - 7.7e-18 64.1 0.0 2.5e-17 62.4 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like T2SJ PF11612.3 CCV00572.1 - 0.00098 18.8 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein J ABC_tran PF00005.22 CCV00573.1 - 5.8e-21 75.2 0.0 1.9e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCV00573.1 - 1e-08 35.5 0.0 0.0028 17.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CCV00573.1 - 0.0022 18.1 0.0 0.45 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCV00573.1 - 0.0022 17.4 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 CCV00573.1 - 0.0023 17.8 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 CCV00573.1 - 0.004 17.0 0.0 0.02 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCV00573.1 - 0.01 15.5 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CCV00573.1 - 0.016 15.1 5.1 0.019 14.9 0.4 2.9 3 1 0 3 3 3 0 AAA ATPase domain Miro PF08477.8 CCV00573.1 - 0.024 15.1 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_25 PF13481.1 CCV00573.1 - 0.029 13.7 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 CCV00573.1 - 0.053 12.8 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_23 PF13476.1 CCV00573.1 - 0.054 13.8 0.0 0.085 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 CCV00573.1 - 0.066 12.2 0.0 0.58 9.1 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_24 PF13479.1 CCV00573.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CCV00573.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 CCV00573.1 - 0.18 10.9 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pantoate_transf PF02548.10 CCV00574.1 - 6.2e-78 261.5 1.4 2.3e-74 249.7 0.7 2.2 1 1 1 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 CCV00574.1 - 0.0036 16.5 0.2 0.0068 15.6 0.1 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Med25_SD1 PF11235.3 CCV00574.1 - 0.021 15.1 0.6 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 Peptidase_C2 PF00648.16 CCV00575.1 - 2e-13 49.9 0.0 3.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 CCV00575.1 - 1.3e-08 34.5 0.0 2.2e-07 30.6 0.0 2.5 2 1 0 2 2 2 1 Calpain large subunit, domain III RNase_T PF00929.19 CCV00576.1 - 1e-18 68.1 0.1 3.1e-18 66.6 0.0 1.7 1 1 0 1 1 1 1 Exonuclease Lectin_leg-like PF03388.8 CCV00577.1 - 2.3e-58 197.0 0.1 3.7e-58 196.3 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 CCV00577.1 - 0.00023 20.5 0.0 0.72 9.1 0.0 2.4 2 1 0 2 2 2 2 Legume lectin domain DUF2648 PF10855.3 CCV00577.1 - 0.4 10.1 2.5 0.88 9.0 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Y_phosphatase PF00102.22 CCV00578.1 - 1.3e-57 194.9 0.8 2.9e-57 193.7 0.6 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 CCV00578.1 - 1.1e-11 45.0 0.0 1.2e-09 38.5 0.0 2.6 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 CCV00578.1 - 0.00042 19.8 0.0 0.00099 18.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCV00578.1 - 0.0094 16.2 0.1 0.05 13.8 0.1 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CCV00578.1 - 0.083 12.9 0.0 0.27 11.2 0.0 1.7 1 1 0 1 1 1 0 Inositol hexakisphosphate IncA PF04156.9 CCV00579.1 - 0.42 10.1 73.5 1.3 8.5 12.5 5.1 1 1 3 4 4 4 0 IncA protein HTH_6 PF01418.12 CCV00579.1 - 3.6 7.3 10.6 0.15 11.8 1.9 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family WD40 PF00400.27 CCV00580.1 - 3.5e-16 58.3 19.0 1.7e-07 30.8 0.1 5.4 5 1 0 5 5 5 4 WD domain, G-beta repeat RWD PF05773.17 CCV00580.1 - 0.0024 17.7 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 CCV00580.1 - 0.055 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme BBS2_C PF14782.1 CCV00580.1 - 0.28 9.6 0.0 0.41 9.1 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Uso1_p115_head PF04869.9 CCV00582.1 - 6.8e-55 186.0 0.0 1.7e-54 184.6 0.0 1.7 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 CCV00582.1 - 0.00011 22.1 17.3 0.00011 22.1 12.0 2.6 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4042 PF13251.1 CCV00582.1 - 0.0093 15.4 1.4 1.2 8.5 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4042) HALZ PF02183.13 CCV00582.1 - 0.6 9.8 7.7 1.6 8.5 1.2 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc7 PF08317.6 CCV00582.1 - 3.8 6.0 14.6 0.49 9.0 2.8 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein FMN_dh PF01070.13 CCV00583.1 - 7.8e-111 370.3 0.0 1.1e-110 369.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CCV00583.1 - 1.3e-22 79.3 0.0 2.4e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CCV00583.1 - 3.3e-06 26.2 0.0 5.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CCV00583.1 - 0.0025 16.7 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain G-alpha PF00503.15 CCV00584.1 - 5.1e-60 203.2 0.1 5.7e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCV00584.1 - 1.2e-06 27.8 0.1 3.3e-06 26.4 0.1 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family HEAT_2 PF13646.1 CCV00585.1 - 5.8e-29 100.2 113.6 6.3e-09 36.0 0.4 17.4 10 5 5 16 16 16 11 HEAT repeats HEAT PF02985.17 CCV00585.1 - 3.4e-23 79.5 59.4 0.019 15.0 0.2 23.0 24 0 0 24 24 24 8 HEAT repeat DUF3554 PF12074.3 CCV00585.1 - 3.7e-20 72.6 7.4 5.2e-15 55.7 0.0 6.4 6 1 1 7 7 7 2 Domain of unknown function (DUF3554) Vac14_Fab1_bd PF12755.2 CCV00585.1 - 6.7e-08 32.8 0.0 1.1 9.6 0.0 7.6 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CCV00585.1 - 2.1e-07 31.2 1.2 2.7e-05 24.4 0.2 24.9 19 8 11 30 30 30 11 HEAT-like repeat Cnd1 PF12717.2 CCV00585.1 - 1.5e-06 28.1 0.0 2.2 8.1 0.0 7.3 5 3 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 CCV00585.1 - 5.6e-05 22.6 5.4 2.3 7.4 0.0 6.5 5 2 3 8 8 8 3 CLASP N terminal RIX1 PF08167.7 CCV00585.1 - 0.0017 18.0 0.8 0.96 9.1 0.0 5.1 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 CCV00585.1 - 0.0019 16.5 5.7 3.5 5.8 0.0 6.2 5 2 1 7 7 7 1 Adaptin N terminal region Arm PF00514.18 CCV00585.1 - 0.0065 16.2 15.7 1.8 8.4 0.0 9.2 10 0 0 10 10 10 2 Armadillo/beta-catenin-like repeat DUF2669 PF10876.3 CCV00585.1 - 0.042 13.5 0.3 20 4.9 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2669) Cyclin PF08613.6 CCV00586.1 - 6.4e-08 33.1 0.1 1.6e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCV00586.1 - 1.4e-07 31.0 0.0 2.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Adeno_PV PF03910.8 CCV00586.1 - 0.092 11.7 4.4 0.13 11.2 3.1 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV ABC_tran PF00005.22 CCV00587.1 - 6.3e-60 201.4 0.0 8.9e-29 100.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCV00587.1 - 1.2e-43 149.4 1.1 8.8e-22 77.8 0.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 CCV00587.1 - 1.5e-10 41.5 0.0 0.11 12.4 0.0 4.1 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 CCV00587.1 - 2.9e-10 41.0 0.0 0.00044 21.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CCV00587.1 - 3.5e-10 39.4 0.0 0.018 14.2 0.0 3.8 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCV00587.1 - 7.6e-10 38.1 0.3 0.00072 19.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CCV00587.1 - 9.2e-10 38.8 3.6 0.00016 21.7 0.1 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 CCV00587.1 - 8.4e-07 28.9 0.0 0.076 12.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CCV00587.1 - 1.1e-06 28.8 0.0 0.18 11.9 0.0 4.1 4 1 0 4 4 4 2 AAA domain AAA_10 PF12846.2 CCV00587.1 - 1.3e-06 28.1 0.5 0.55 9.6 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_25 PF13481.1 CCV00587.1 - 1.4e-06 27.8 8.2 0.0044 16.4 1.7 3.6 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 CCV00587.1 - 1.3e-05 23.9 2.9 0.00076 18.1 0.0 3.4 4 0 0 4 4 4 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 CCV00587.1 - 1.7e-05 24.6 2.5 0.29 11.0 0.0 4.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 CCV00587.1 - 2.4e-05 24.6 0.0 0.065 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 CCV00587.1 - 2.6e-05 23.9 0.1 0.006 16.2 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_28 PF13521.1 CCV00587.1 - 5.4e-05 23.1 0.1 0.14 12.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.1 CCV00587.1 - 0.0001 21.9 0.4 0.79 9.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 CCV00587.1 - 0.00011 21.9 0.2 0.42 10.2 0.0 2.9 3 0 0 3 3 3 2 NACHT domain MobB PF03205.9 CCV00587.1 - 0.00013 21.6 0.1 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 CCV00587.1 - 0.00018 21.2 0.1 0.81 9.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 CCV00587.1 - 0.00024 20.3 0.0 0.33 10.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 CCV00587.1 - 0.00092 19.0 1.1 0.24 11.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 CCV00587.1 - 0.00092 18.3 0.0 0.43 9.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin SRP54 PF00448.17 CCV00587.1 - 0.0016 17.9 0.1 0.21 11.0 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 CCV00587.1 - 0.0028 17.5 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CCV00587.1 - 0.0044 17.4 0.1 0.62 10.5 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 CCV00587.1 - 0.0072 16.5 0.0 4.6 7.4 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 CCV00587.1 - 0.013 14.9 0.0 4.2 6.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 CCV00587.1 - 0.024 14.1 0.1 0.54 9.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 CCV00587.1 - 0.029 13.9 0.1 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.15 CCV00587.1 - 0.033 12.8 0.0 3.3 6.3 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit ATP-synt_ab PF00006.20 CCV00587.1 - 0.039 13.4 0.0 4 6.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 CCV00587.1 - 0.074 13.0 0.0 7.4 6.5 0.0 2.6 3 0 0 3 3 2 0 50S ribosome-binding GTPase ResIII PF04851.10 CCV00587.1 - 0.085 12.6 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 CCV00587.1 - 0.086 13.0 0.1 10 6.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase CbiA PF01656.18 CCV00587.1 - 0.11 11.8 4.2 3.4 7.0 0.0 3.4 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.1 CCV00587.1 - 0.11 12.8 0.0 21 5.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CCV00587.1 - 0.13 11.0 0.7 6 5.6 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 CCV00587.1 - 0.15 11.6 0.3 10 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain PEPCK_ATP PF01293.15 CCV00587.1 - 0.16 10.4 0.0 5.5 5.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase PduV-EutP PF10662.4 CCV00587.1 - 0.21 11.0 0.3 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.13 CCV00587.1 - 0.3 10.5 0.0 21 4.6 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KaiC PF06745.8 CCV00587.1 - 0.39 9.7 0.4 4.6 6.2 0.0 2.2 2 0 0 2 2 2 0 KaiC Thymidylate_kin PF02223.12 CCV00587.1 - 0.4 10.0 0.0 18 4.6 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase Pox_A32 PF04665.7 CCV00587.1 - 0.43 9.8 0.2 1.5 8.0 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein HSP70 PF00012.15 CCV00588.1 - 1.4e-237 789.4 3.7 1.8e-237 789.0 2.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCV00588.1 - 8.1e-17 60.8 0.2 1.3e-16 60.1 0.2 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.5 CCV00588.1 - 0.0037 16.1 0.8 0.034 12.9 0.3 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 CCV00588.1 - 0.0092 15.1 0.2 0.1 11.6 0.0 2.5 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase StbA PF06406.6 CCV00588.1 - 0.015 14.2 0.0 0.027 13.4 0.0 1.5 1 0 0 1 1 1 0 StbA protein QRPTase_N PF02749.11 CCV00588.1 - 0.048 13.4 0.1 7.1 6.5 0.0 3.2 2 1 1 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain FGGY_C PF02782.11 CCV00588.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Ribosomal_S2 PF00318.15 CCV00589.1 - 8e-44 149.3 0.0 9.8e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 RNA_pol_L PF01193.19 CCV00589.1 - 0.046 12.8 0.0 3.5 6.8 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain SNF5 PF04855.7 CCV00590.1 - 1.8e-61 207.6 0.0 2.6e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 CCV00590.1 - 1.4e-06 27.5 1.0 2.9e-06 26.4 0.7 1.6 1 0 0 1 1 1 1 GATA zinc finger PITH PF06201.8 CCV00591.1 - 4.1e-31 107.7 0.0 5.1e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain UPF0016 PF01169.14 CCV00593.1 - 5.1e-41 138.6 18.8 1.8e-20 72.8 1.5 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 CCV00593.1 - 0.0011 18.4 4.5 0.15 11.4 0.0 2.3 2 0 0 2 2 2 2 Integral membrane protein TerC family TauE PF01925.14 CCV00593.1 - 0.0081 15.6 15.6 0.05 13.0 10.9 1.9 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE LysE PF01810.13 CCV00593.1 - 0.048 12.9 11.5 0.18 11.0 0.6 2.3 2 0 0 2 2 2 0 LysE type translocator MFS_1 PF07690.11 CCV00593.1 - 0.11 11.1 13.5 0.24 10.0 6.5 2.1 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF21 PF01595.15 CCV00593.1 - 0.16 11.2 9.2 1.2 8.3 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF21 DUF4131 PF13567.1 CCV00593.1 - 0.2 11.0 8.8 0.51 9.7 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) FAM70 PF14967.1 CCV00593.1 - 0.48 9.5 5.1 8 5.5 1.2 2.3 2 1 0 2 2 2 0 FAM70 protein DUF204 PF02659.10 CCV00593.1 - 0.74 9.9 13.0 0.36 10.9 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF Herpes_US9 PF06072.6 CCV00593.1 - 2.2 8.1 8.5 8.5 6.2 2.2 2.7 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Sad1_UNC PF07738.8 CCV00594.1 - 1.1e-27 96.5 0.0 1.8e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RhoGEF PF00621.15 CCV00595.1 - 5.3e-30 104.6 0.0 2.2e-29 102.5 0.0 2.0 1 1 0 1 1 1 1 RhoGEF domain Cellulase PF00150.13 CCV00595.1 - 2.1e-14 53.4 2.1 3.9e-14 52.5 1.5 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2106 PF09879.4 CCV00595.1 - 0.39 10.0 0.0 5.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2106) BAR PF03114.13 CCV00595.1 - 0.97 8.8 1.8 3.9 6.9 1.2 1.8 1 1 0 1 1 1 0 BAR domain Hexapep PF00132.19 CCV00596.1 - 2.9e-12 45.5 7.8 1e-05 24.8 0.3 4.8 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CCV00596.1 - 1.5e-05 24.4 8.1 0.0007 19.1 0.7 3.5 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 CCV00596.1 - 0.0078 14.8 0.0 0.0098 14.4 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase NAPRTase PF04095.11 CCV00597.1 - 5.7e-36 124.0 0.0 8.3e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family EF-hand_6 PF13405.1 CCV00598.1 - 2.5e-06 26.8 0.1 0.032 14.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CCV00598.1 - 5.3e-06 26.4 0.1 0.034 14.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CCV00598.1 - 0.00033 19.7 0.3 0.62 9.5 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CCV00598.1 - 0.0077 15.8 0.1 0.18 11.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CCV00598.1 - 0.074 12.4 0.6 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 EF hand UPF0220 PF05255.6 CCV00599.1 - 7.5e-45 152.1 0.3 8.5e-45 151.9 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) PgpA PF04608.8 CCV00599.1 - 0.25 11.1 4.8 0.27 11.0 0.2 2.4 2 1 0 2 2 2 0 Phosphatidylglycerophosphatase A Myb_Cef PF11831.3 CCV00600.1 - 2.4e-20 72.7 0.0 2.4e-20 72.7 0.0 3.3 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 CCV00600.1 - 1.9e-14 53.4 7.4 1.9e-08 34.2 2.4 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCV00600.1 - 4.1e-13 49.1 6.3 5.9e-08 32.6 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Aminotran_1_2 PF00155.16 CCV00601.1 - 3.8e-54 184.0 0.0 4.9e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CCV00601.1 - 0.045 12.4 0.0 0.12 11.0 0.0 1.6 1 1 1 2 2 2 0 Aminotransferase class-V Med17 PF10156.4 CCV00602.1 - 8.5e-12 44.0 0.0 2.8e-06 25.8 0.0 2.0 2 0 0 2 2 2 2 Subunit 17 of Mediator complex FKBP_C PF00254.23 CCV00603.1 - 3.8e-32 110.1 0.0 4.8e-32 109.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase LSM PF01423.17 CCV00604.1 - 1.4e-11 43.7 0.0 2.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain TraQ PF09679.5 CCV00604.1 - 0.044 13.6 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) SBP PF03110.9 CCV00604.1 - 0.078 13.2 0.2 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 SBP domain zf-CCCH_2 PF14608.1 CCV00605.1 - 3.4e-06 26.8 37.6 0.021 14.8 0.5 4.8 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type DUF2890 PF11081.3 CCV00605.1 - 0.65 10.0 5.4 1.4 8.9 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF997 PF06196.7 CCV00606.1 - 0.19 11.2 0.0 0.19 11.2 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF997) PseudoU_synth_2 PF00849.17 CCV00607.1 - 3.2e-22 79.1 0.0 5.8e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase MMR_HSR1 PF01926.18 CCV00609.1 - 1.2e-11 44.6 0.0 1.8e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.8 CCV00609.1 - 0.0037 16.1 0.0 0.0062 15.3 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 CCV00609.1 - 0.01 15.0 0.0 0.024 13.9 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.1 CCV00609.1 - 0.049 13.6 0.2 0.16 11.9 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 CCV00609.1 - 0.061 13.1 0.2 0.27 11.0 0.1 1.9 2 0 0 2 2 2 0 Dynamin family AAA_29 PF13555.1 CCV00609.1 - 0.085 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 CCV00609.1 - 0.099 11.8 0.2 0.37 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 CCV00609.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Arrestin_C PF02752.17 CCV00610.1 - 0.23 11.5 0.0 0.54 10.3 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain MIF4G PF02854.14 CCV00611.1 - 2.3e-54 184.0 0.2 7.9e-54 182.2 0.3 1.9 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.3 CCV00611.1 - 9.9e-19 67.0 0.1 5.5e-18 64.6 0.1 2.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 CCV00611.1 - 2.4e-11 43.3 0.6 1.1e-10 41.2 0.0 2.3 3 0 0 3 3 3 1 MA3 domain Plasmodium_HRP PF05403.6 CCV00611.1 - 0.00035 20.2 32.4 0.00035 20.2 22.5 1.7 2 0 0 2 2 2 1 Plasmodium histidine-rich protein (HRPII/III) Bromodomain PF00439.20 CCV00612.1 - 1.1e-07 31.6 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 CCV00612.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated tRNA-synt_2 PF00152.15 CCV00613.1 - 3.7e-62 210.0 0.0 6.2e-62 209.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCV00613.1 - 1.2e-09 37.8 0.0 2.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1682 PF07946.9 CCV00613.1 - 0.021 13.6 4.7 0.04 12.7 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Peptidase_S8 PF00082.17 CCV00614.1 - 5.1e-50 170.1 3.4 7.6e-50 169.6 2.4 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CCV00614.1 - 9.7e-11 42.0 0.0 2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 GIT_SHD PF08518.6 CCV00615.1 - 9.2e-22 76.0 8.5 1.8e-12 46.3 1.6 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT TMF_DNA_bd PF12329.3 CCV00615.1 - 0.13 12.0 18.6 0.02 14.6 3.2 3.2 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CCV00615.1 - 1.1 8.8 42.3 0.69 9.4 10.3 4.3 3 1 1 4 4 4 0 IncA protein CENP-F_leu_zip PF10473.4 CCV00615.1 - 1.6 8.5 30.9 4.3 7.1 3.4 4.3 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 CCV00615.1 - 3.6 7.6 8.1 5.1 7.1 0.9 3.9 2 1 1 3 3 3 0 bZIP transcription factor Filament PF00038.16 CCV00615.1 - 7.1 5.9 36.7 0.25 10.7 19.4 2.8 3 1 0 3 3 3 0 Intermediate filament protein Mito_carr PF00153.22 CCV00616.1 - 6.5e-68 224.4 2.6 6.4e-22 77.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_6 PF14259.1 CCV00617.1 - 4.8e-39 132.1 0.3 2.8e-10 40.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCV00617.1 - 3.4e-29 100.2 0.0 4.8e-09 35.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCV00617.1 - 2.3e-19 69.0 0.0 1.1e-05 25.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCV00617.1 - 0.068 12.9 0.0 6.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif ER_lumen_recept PF00810.13 CCV00618.1 - 7e-49 166.1 8.6 9.1e-49 165.7 6.0 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CCV00618.1 - 0.031 13.8 1.1 0.031 13.8 0.7 4.0 4 1 1 5 5 5 0 PQ loop repeat NMO PF03060.10 CCV00619.1 - 2.5e-49 168.2 3.6 1e-48 166.2 2.5 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CCV00619.1 - 2.5e-06 26.6 1.6 0.0073 15.2 0.0 2.5 1 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain DUF1902 PF08972.6 CCV00619.1 - 0.048 13.2 0.3 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Zip PF02535.17 CCV00620.1 - 2.9e-26 92.2 5.8 2.9e-26 92.2 4.0 2.8 1 1 1 2 2 2 1 ZIP Zinc transporter BCLP PF12304.3 CCV00620.1 - 0.00042 19.7 1.3 0.001 18.5 0.9 1.7 1 0 0 1 1 1 1 Beta-casein like protein Peptidase_S58 PF03576.9 CCV00620.1 - 0.05 12.7 0.3 0.082 12.0 0.2 1.3 1 0 0 1 1 1 0 Peptidase family S58 Ribonuclease_T2 PF00445.13 CCV00622.1 - 4.7e-36 124.1 1.5 7.3e-36 123.5 1.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family RNA_pol_Rpb1_5 PF04998.12 CCV00623.1 - 4.8e-83 278.6 0.0 8.8e-83 277.7 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CCV00623.1 - 1.2e-60 204.2 0.0 2.2e-60 203.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CCV00623.1 - 1.8e-35 121.9 0.0 3.4e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 CCV00623.1 - 2e-25 89.7 0.0 1.1e-21 77.4 0.0 3.3 2 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 CCV00623.1 - 1.4e-19 69.7 0.0 3.7e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 ThiF PF00899.16 CCV00624.1 - 2e-34 118.3 0.0 3.2e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family FAD_binding_3 PF01494.14 CCV00624.1 - 0.018 14.1 0.2 0.03 13.3 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 CCV00624.1 - 0.022 13.6 0.2 0.039 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 CCV00624.1 - 0.1 12.0 0.2 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 CCV00624.1 - 0.12 12.0 0.4 0.54 9.8 0.0 2.2 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6PF2K PF01591.13 CCV00625.1 - 1.1e-69 233.8 0.0 1.5e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCV00625.1 - 1.7e-28 99.6 0.0 3.8e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CCV00625.1 - 4e-08 33.2 0.5 7.7e-08 32.3 0.4 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCV00625.1 - 0.00077 20.2 0.0 0.0061 17.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.5 CCV00625.1 - 0.0038 16.4 0.0 0.0075 15.4 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 GBP PF02263.14 CCV00625.1 - 0.042 12.9 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Peptidase_M24 PF00557.19 CCV00626.1 - 2.3e-42 144.9 0.1 3.1e-42 144.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 HSP90 PF00183.13 CCV00626.1 - 0.19 10.0 6.4 0.28 9.5 4.5 1.1 1 0 0 1 1 1 0 Hsp90 protein Cnd2 PF05786.9 CCV00626.1 - 0.88 7.9 8.9 1.2 7.5 6.1 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 TATR PF03430.8 CCV00626.1 - 2.2 6.8 5.3 2.9 6.4 3.7 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator RR_TM4-6 PF06459.7 CCV00626.1 - 3.3 7.5 8.2 5.2 6.8 5.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_H2-Ydr279 PF09468.5 CCV00626.1 - 4 6.5 8.7 6.3 5.9 6.1 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CDC45 PF02724.9 CCV00626.1 - 4.4 5.2 7.3 6.2 4.7 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein UQ_con PF00179.21 CCV00627.1 - 2e-34 117.9 0.0 2.2e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rhodanese PF00581.15 CCV00628.1 - 4.1e-18 65.7 0.0 1.3e-10 41.6 0.0 2.7 2 1 0 2 2 2 2 Rhodanese-like domain Arrestin_C PF02752.17 CCV00629.1 - 4.9e-17 62.3 0.0 3.1e-14 53.2 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCV00629.1 - 2.4e-15 56.6 0.0 1.1e-10 41.5 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CCV00629.1 - 1.4e-06 27.9 0.0 2.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like DUF3414 PF11894.3 CCV00630.1 - 7.1e-08 29.8 0.1 1.5e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Macro PF01661.16 CCV00631.1 - 1.2e-10 41.3 0.0 2e-10 40.6 0.0 1.4 2 0 0 2 2 2 1 Macro domain Romo1 PF10247.4 CCV00632.1 - 2.4e-21 75.7 14.2 2.9e-21 75.4 9.9 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Methyltransf_12 PF08242.7 CCV00633.1 - 4.7e-10 39.8 0.0 1.1e-09 38.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCV00633.1 - 1.6e-07 31.2 0.0 2.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCV00633.1 - 1.7e-06 28.5 0.0 2.6e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCV00633.1 - 1.3e-05 25.4 0.0 3.8e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCV00633.1 - 3.8e-05 23.3 0.0 7.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCV00633.1 - 4e-05 23.0 0.0 6.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CCV00633.1 - 0.00013 22.0 0.1 0.00038 20.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCV00633.1 - 0.00031 21.1 0.0 0.00093 19.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain FmrO PF07091.6 CCV00633.1 - 0.0092 15.0 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Nucleoporin_C PF03177.9 CCV00634.1 - 2e-44 152.1 7.0 3.3e-44 151.3 4.8 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CCV00634.1 - 1.6e-06 27.1 0.0 4.1e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Nup133 N terminal like DUF1682 PF07946.9 CCV00635.1 - 1.9e-43 148.5 0.0 2.2e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) USP7_ICP0_bdg PF12436.3 CCV00636.1 - 2.5e-80 269.3 1.1 3.1e-80 268.9 0.3 1.5 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 CCV00636.1 - 5.1e-61 205.8 7.3 1.2e-60 204.5 0.7 3.0 3 1 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 CCV00636.1 - 3.2e-56 190.4 0.2 5.7e-56 189.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCV00636.1 - 1.1e-29 103.8 0.0 1.9e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 CCV00636.1 - 2e-09 37.7 0.1 8.2e-08 32.5 0.0 3.4 2 2 1 3 3 3 1 MATH domain Acetyltransf_1 PF00583.19 CCV00637.1 - 1e-11 44.6 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCV00637.1 - 1.1e-09 38.2 0.0 1.7e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCV00637.1 - 2.1e-05 24.6 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCV00637.1 - 0.0044 16.8 0.0 0.0073 16.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCV00637.1 - 0.0074 16.4 0.0 0.0097 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCV00637.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 CCV00637.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Chalcone PF02431.10 CCV00638.1 - 1.5e-29 102.8 0.0 2.6e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Abhydrolase_6 PF12697.2 CCV00638.1 - 7.1e-23 81.6 0.0 1.7e-22 80.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCV00638.1 - 2.9e-15 56.3 0.0 5.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CCV00638.1 - 2e-09 37.3 0.0 3.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 CCV00638.1 - 4.1e-09 36.3 0.0 8.8e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 CCV00638.1 - 3.9e-05 23.0 0.0 6.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 CCV00638.1 - 6.2e-05 23.3 0.0 0.0001 22.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 CCV00638.1 - 0.00017 21.3 0.0 0.00038 20.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 CCV00638.1 - 0.00062 18.6 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Lipase_3 PF01764.20 CCV00638.1 - 0.00086 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase2 PF12740.2 CCV00638.1 - 0.001 18.0 0.0 0.0018 17.1 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme LCAT PF02450.10 CCV00638.1 - 0.043 12.7 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 CCV00638.1 - 0.089 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Arrestin_N PF00339.24 CCV00639.1 - 0.023 14.4 0.2 7.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Phosphoprotein PF00922.12 CCV00639.1 - 0.2 10.8 6.2 0.27 10.4 3.3 1.8 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein PerB PF06590.6 CCV00641.1 - 0.006 16.8 0.1 2.3 8.5 0.0 2.2 2 0 0 2 2 2 2 PerB protein CaM-KIIN PF15170.1 CCV00641.1 - 0.018 15.0 0.4 8.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Calcium/calmodulin-dependent protein kinase II inhibitor DUF1411 PF07199.6 CCV00641.1 - 0.073 12.4 0.3 3.8 6.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) AcylCoA_DH_N PF12418.3 CCV00641.1 - 0.14 11.8 0.0 21 4.8 0.0 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase N terminal Asp PF00026.18 CCV00642.1 - 3.8e-48 164.3 2.3 8.7e-48 163.1 1.6 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCV00642.1 - 3.1e-05 24.3 0.1 0.4 11.1 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 CCV00642.1 - 4.6e-05 23.0 0.2 0.00011 21.8 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 CCV00642.1 - 8.4e-05 22.5 0.9 0.0011 18.9 0.6 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal CactinC_cactus PF09732.4 CCV00645.1 - 1.9e-55 185.7 4.3 2.9e-55 185.2 3.0 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 CCV00645.1 - 1.1e-41 142.2 0.7 2e-41 141.3 0.5 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin AD PF09793.4 CCV00646.1 - 5.6e-13 48.5 0.0 9e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain L51_S25_CI-B8 PF05047.11 CCV00647.1 - 1.8e-06 27.6 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain eRF1_1 PF03463.10 CCV00648.1 - 1.7e-45 153.8 0.0 2.9e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 CCV00648.1 - 1.4e-21 76.8 0.0 2.3e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 CCV00648.1 - 9.2e-19 68.0 0.0 1.3e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 2 Myosin_tail_1 PF01576.14 CCV00649.1 - 0.00059 17.7 10.2 0.00088 17.1 7.1 1.1 1 0 0 1 1 1 1 Myosin tail Macoilin PF09726.4 CCV00649.1 - 0.053 11.8 11.0 0.0048 15.2 4.2 1.7 2 0 0 2 2 2 0 Transmembrane protein DUF3373 PF11853.3 CCV00649.1 - 0.96 7.9 3.2 1.5 7.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Spc7 PF08317.6 CCV00649.1 - 2 7.0 12.1 0.09 11.4 4.5 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein HCO3_cotransp PF00955.16 CCV00651.1 - 3.3e-37 128.3 16.2 1.3e-15 57.0 0.6 3.1 2 1 1 3 3 3 3 HCO3- transporter family RNA_pol_Rpb4 PF03874.11 CCV00652.1 - 2.2e-23 82.4 0.1 3e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Ribosomal_S18 PF01084.15 CCV00653.1 - 1.1e-18 66.7 0.0 1.8e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 HK PF02110.10 CCV00654.1 - 1.4e-64 217.6 3.0 1.4e-61 207.7 3.6 2.2 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 CCV00654.1 - 7e-39 132.7 0.0 1.3e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 CCV00654.1 - 0.00061 19.0 0.5 0.00098 18.3 0.3 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Sld5 PF05916.6 CCV00655.1 - 4.2e-07 30.2 0.4 5.4e-07 29.8 0.3 1.2 1 0 0 1 1 1 1 GINS complex protein Sec10 PF07393.6 CCV00656.1 - 1.6e-219 730.6 0.0 2e-219 730.4 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DisA-linker PF10635.4 CCV00656.1 - 0.093 12.2 1.2 0.25 10.8 0.8 1.7 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Tropomyosin_1 PF12718.2 CCV00656.1 - 0.097 12.5 0.8 0.18 11.6 0.6 1.4 1 0 0 1 1 1 0 Tropomyosin like DUF4265 PF14085.1 CCV00656.1 - 0.13 12.0 0.1 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Occludin_ELL PF07303.8 CCV00656.1 - 0.13 12.9 1.3 0.35 11.6 0.5 2.0 1 1 0 1 1 1 0 Occludin homology domain RIX1 PF08167.7 CCV00657.1 - 0.00097 18.8 0.1 0.0022 17.7 0.1 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Pex2_Pex12 PF04757.9 CCV00658.1 - 8.1e-34 117.0 10.5 1.4e-33 116.2 7.2 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-like PF04071.7 CCV00658.1 - 0.051 13.2 3.5 0.13 11.9 2.4 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain Acid_PPase PF12689.2 CCV00659.1 - 1.4e-15 57.3 0.1 1.5e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Acid_PPase PF12689.2 CCV00660.1 - 0.0014 18.3 0.0 0.0017 18.0 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase Hist_deacetyl PF00850.14 CCV00661.1 - 1.2e-76 257.9 0.0 1.6e-76 257.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain TPR_11 PF13414.1 CCV00662.1 - 6.9e-25 86.4 3.8 4.5e-05 23.0 0.0 6.7 6 0 0 6 6 6 5 TPR repeat TPR_16 PF13432.1 CCV00662.1 - 7.3e-19 67.9 5.4 0.00025 21.6 0.1 6.2 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 CCV00662.1 - 6.1e-15 53.8 6.5 2.7 8.1 0.0 9.5 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCV00662.1 - 1.4e-13 49.7 7.6 0.064 12.8 0.0 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCV00662.1 - 3.2e-13 49.0 11.5 0.0023 18.3 0.2 9.0 6 2 3 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCV00662.1 - 3.2e-11 43.3 8.5 0.00029 21.1 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCV00662.1 - 1.4e-10 40.9 6.2 0.08 12.8 0.0 6.3 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCV00662.1 - 1.4e-09 37.0 1.0 0.59 10.0 0.0 8.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCV00662.1 - 2.2e-09 37.1 4.8 3.2 8.3 0.0 9.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCV00662.1 - 5.4e-07 29.3 7.4 0.013 15.3 0.2 6.4 5 2 2 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 CCV00662.1 - 1.5e-06 28.2 0.9 0.47 10.6 0.1 4.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CCV00662.1 - 5.4e-06 26.2 1.0 7.5 7.0 0.0 6.8 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCV00662.1 - 0.00059 19.4 3.4 2.7 7.9 0.1 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CCV00662.1 - 0.0019 18.4 0.2 1.2 9.3 0.0 2.5 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation TPR_15 PF13429.1 CCV00662.1 - 0.0022 17.1 2.2 0.086 11.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 CCV00662.1 - 0.0023 18.0 5.2 2.4 8.3 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat NatB_MDM20 PF09797.4 CCV00662.1 - 0.058 12.1 2.5 3.2 6.3 0.0 3.0 3 0 0 3 3 3 0 N-acetyltransferase B complex (NatB) non catalytic subunit NARP1 PF12569.3 CCV00662.1 - 0.058 12.1 0.1 30 3.2 0.0 3.2 3 1 0 3 3 3 0 NMDA receptor-regulated protein 1 HEPN PF05168.9 CCV00662.1 - 0.16 11.8 1.4 24 4.8 0.0 3.6 3 0 0 3 3 3 0 HEPN domain TPR_10 PF13374.1 CCV00662.1 - 3.4 7.7 8.6 1.1 9.2 0.1 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat WBS_methylT PF12589.3 CCV00663.1 - 1.2e-18 67.3 4.5 2.1e-18 66.5 3.2 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 CCV00663.1 - 7e-09 36.0 0.0 1.5e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCV00663.1 - 3.5e-08 33.3 0.0 5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCV00663.1 - 1.7e-05 24.4 0.0 3.6e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCV00663.1 - 6.9e-05 23.4 0.1 0.00012 22.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCV00663.1 - 9.4e-05 22.7 0.0 0.00021 21.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCV00663.1 - 0.00011 22.5 0.7 0.00088 19.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain AdoMet_MTase PF07757.8 CCV00663.1 - 0.0059 16.7 0.0 0.017 15.2 0.0 1.7 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase N6_N4_Mtase PF01555.13 CCV00663.1 - 0.011 15.2 0.0 0.044 13.2 0.0 1.8 2 0 0 2 2 2 0 DNA methylase Methyltransf_26 PF13659.1 CCV00663.1 - 0.031 14.3 0.0 0.067 13.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 CCV00663.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.14 CCV00663.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Syntaxin-18_N PF10496.4 CCV00664.1 - 3.1e-11 42.9 1.0 3.6e-10 39.5 0.0 3.0 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus DUF1451 PF07295.6 CCV00664.1 - 5.5 6.7 12.1 0.59 9.8 1.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1451) Tropomyosin_1 PF12718.2 CCV00664.1 - 8.2 6.2 11.6 2.9 7.7 3.8 2.4 2 0 0 2 2 2 0 Tropomyosin like BCDHK_Adom3 PF10436.4 CCV00665.1 - 1.2e-23 83.4 4.8 1.9e-23 82.8 3.3 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCV00665.1 - 5.9e-05 22.7 0.0 0.057 13.1 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nop14 PF04147.7 CCV00665.1 - 6.5 4.5 13.8 9.5 3.9 9.6 1.2 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 CCV00666.1 - 3.6e-71 239.3 0.0 5e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCV00666.1 - 1.6e-32 112.6 0.0 5.1e-32 110.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCV00666.1 - 0.0001 21.3 0.4 0.099 11.5 0.0 3.6 3 1 0 3 3 3 1 Kinase-like APH PF01636.18 CCV00666.1 - 0.00027 20.7 0.5 0.46 10.1 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 CCV00666.1 - 0.00031 20.1 0.2 0.00064 19.1 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Sua5_yciO_yrdC PF01300.13 CCV00667.1 - 2.3e-52 176.8 0.0 3.2e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 CCV00667.1 - 7.4e-28 97.1 0.0 1.2e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding AMP-binding PF00501.23 CCV00668.1 - 4.8e-78 262.4 0.1 7.2e-78 261.8 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CCV00668.1 - 4.9e-70 235.2 0.1 8.1e-69 231.2 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 CCV00668.1 - 4.2e-12 46.1 0.0 1e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 CCV00668.1 - 1.4e-11 44.3 0.1 2.9e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 CCV00668.1 - 9.7e-10 39.2 0.1 7.3e-09 36.4 0.0 2.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 CCV00668.1 - 2.7e-06 26.3 0.0 1.6e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 CCV00668.1 - 7.6e-05 21.7 0.0 0.00016 20.6 0.0 1.5 1 0 0 1 1 1 1 Condensation domain Polysacc_synt_2 PF02719.10 CCV00668.1 - 0.14 11.0 0.0 1 8.2 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein VCBS PF13517.1 CCV00669.1 - 9.3e-17 61.1 8.9 0.00019 21.7 0.0 5.3 5 1 1 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CCV00669.1 - 1.2e-12 47.1 4.9 0.057 13.1 0.0 6.0 6 0 0 6 6 6 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 CCV00669.1 - 0.0035 16.7 1.2 1.3 8.4 0.0 3.6 3 1 1 4 4 4 1 Insecticide toxin TcdB middle/N-terminal region EF-hand_5 PF13202.1 CCV00669.1 - 0.018 14.3 5.6 0.3 10.4 0.1 3.6 4 0 0 4 4 4 0 EF hand V_ATPase_I PF01496.14 CCV00670.1 - 4e-272 904.5 0.0 4.6e-272 904.3 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Cep57_MT_bd PF06657.8 CCV00670.1 - 0.16 11.9 3.9 0.31 11.0 1.3 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4006 PF13179.1 CCV00670.1 - 6.1 6.4 5.9 17 5.0 3.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF4006) PRP21_like_P PF12230.3 CCV00672.1 - 5.6e-44 150.3 1.8 7.3e-23 81.2 0.0 2.6 1 1 1 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CCV00672.1 - 8.3e-31 105.4 0.7 6e-17 61.0 0.0 2.4 2 0 0 2 2 2 2 Surp module PalH PF08733.5 CCV00672.1 - 0.009 14.8 4.3 0.017 14.0 2.9 1.3 1 0 0 1 1 1 1 PalH/RIM21 Chorismate_bind PF00425.13 CCV00673.1 - 4.1e-88 295.0 0.0 5.8e-88 294.5 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 CCV00673.1 - 2e-26 92.6 0.0 7.7e-26 90.7 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region ComZ PF10815.3 CCV00674.1 - 0.02 14.6 0.1 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 ComZ Lipase_3 PF01764.20 CCV00675.1 - 3.5e-07 29.9 0.0 5.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CCV00675.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 CCV00675.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) HAMP PF00672.20 CCV00675.1 - 1 9.5 7.7 3.1 8.0 5.3 1.9 1 1 0 1 1 1 0 HAMP domain GCV_H PF01597.14 CCV00676.1 - 3.3e-15 55.8 0.0 4e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Ribosomal_S19 PF00203.16 CCV00677.1 - 9.9e-25 85.9 0.2 2.9e-24 84.4 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein S19 SSrecog PF03531.9 CCV00678.1 - 3.8e-69 232.4 0.9 3.2e-47 160.7 0.0 3.2 1 1 1 2 2 2 2 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 CCV00678.1 - 1.1e-24 86.1 0.1 9.8e-23 79.9 0.0 2.5 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PRK PF00485.13 CCV00678.1 - 6.6e-05 22.5 0.0 0.013 15.0 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 CCV00678.1 - 0.0052 17.0 0.0 0.038 14.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain zf-C3HC4_3 PF13920.1 CCV00678.1 - 1.6 8.4 10.2 9.2 6.0 7.1 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NRDE PF05742.7 CCV00679.1 - 9.9e-38 129.9 0.0 1.2e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 NRDE protein Arrestin_C PF02752.17 CCV00681.1 - 4.4e-07 30.0 0.7 8.5e-07 29.1 0.3 1.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCV00681.1 - 6.9e-07 29.1 0.0 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain A2M_N PF01835.14 CCV00681.1 - 0.038 14.2 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 MG2 domain Ribonuc_red_lgC PF02867.10 CCV00682.1 - 1.2e-214 713.8 0.0 1.7e-214 713.3 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CCV00682.1 - 5.3e-24 83.8 0.3 4.2e-23 80.9 0.0 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CCV00682.1 - 2.1e-14 53.7 0.2 5.8e-14 52.2 0.2 1.8 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 CCV00682.1 - 0.02 13.0 0.0 0.031 12.3 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase MARVEL PF01284.18 CCV00683.1 - 3.1e-12 46.5 15.6 4.2e-12 46.0 10.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain MscS_TM PF12794.2 CCV00683.1 - 0.018 13.6 4.3 0.03 12.9 2.9 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Yip1 PF04893.12 CCV00683.1 - 2.4 7.6 22.6 4.7e+02 0.1 5.0 2.2 1 1 0 1 1 1 0 Yip1 domain Brix PF04427.13 CCV00684.1 - 1.6e-24 86.6 0.0 2.2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain WD40 PF00400.27 CCV00685.1 - 6.3e-25 86.1 4.2 2.4e-06 27.1 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Methyltransf_16 PF10294.4 CCV00686.1 - 4.2e-11 42.6 0.0 6.5e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CCV00686.1 - 0.00021 21.0 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DNA_processg_A PF02481.10 CCV00686.1 - 0.0041 16.0 0.1 0.0066 15.3 0.1 1.3 1 0 0 1 1 1 1 DNA recombination-mediator protein A Methyltransf_18 PF12847.2 CCV00686.1 - 0.052 14.1 1.5 0.69 10.5 1.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CCV00686.1 - 0.053 12.8 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PTCB-BRCT PF12738.2 CCV00687.1 - 2.4e-20 72.1 0.1 5e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 twin BRCT domain BRCT PF00533.21 CCV00687.1 - 4.5e-15 55.5 0.0 8.1e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain YL1 PF05764.8 CCV00688.1 - 1.6e-42 145.7 17.5 2.6e-42 145.1 12.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 CCV00688.1 - 8.2e-15 54.0 0.1 1.4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ly49 PF08391.5 CCV00688.1 - 0.13 12.4 0.9 0.24 11.5 0.6 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF1856 PF08983.5 CCV00688.1 - 0.81 9.8 3.1 1.9 8.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) DUF4632 PF15451.1 CCV00688.1 - 0.94 9.4 6.9 4.6 7.2 4.8 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) SDA1 PF05285.7 CCV00688.1 - 1.1 8.5 13.7 1.5 7.9 9.5 1.2 1 0 0 1 1 1 0 SDA1 Ribonuc_red_sm PF00268.16 CCV00689.1 - 7.9e-118 392.5 1.8 9.5e-118 392.2 1.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribosomal_L18_c PF14204.1 CCV00689.1 - 0.16 12.5 1.3 1.6 9.3 0.1 2.7 3 0 0 3 3 3 0 Ribosomal L18 C-terminal region Cellulase PF00150.13 CCV00690.1 - 6.7e-18 64.8 2.3 1.2e-17 64.0 1.6 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Plasmodium_HRP PF05403.6 CCV00690.1 - 0.038 13.5 22.4 0.066 12.7 15.5 1.3 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) DUF1510 PF07423.6 CCV00690.1 - 0.061 12.6 13.7 0.16 11.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF566 PF04484.7 CCV00690.1 - 0.78 9.1 50.3 1.5 8.2 12.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF566) DUF605 PF04652.11 CCV00690.1 - 7.3 5.8 38.6 1.6 8.0 9.2 2.2 2 0 0 2 2 2 0 Vta1 like CAP_N PF01213.14 CCV00691.1 - 1.3e-90 303.8 1.9 3.4e-90 302.4 1.3 1.7 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 CCV00691.1 - 1.4e-55 186.9 0.3 2.1e-55 186.3 0.2 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Ndc80_HEC PF03801.8 CCV00691.1 - 1.2e-29 102.7 0.0 2.7e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family TBCC PF07986.7 CCV00691.1 - 0.00091 18.6 1.0 0.0018 17.6 0.7 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C HALZ PF02183.13 CCV00691.1 - 0.27 10.9 12.9 0.28 10.9 0.3 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper WXG100 PF06013.7 CCV00691.1 - 0.45 10.5 9.4 0.75 9.8 0.2 4.6 4 0 0 4 4 4 0 Proteins of 100 residues with WXG Pex2_Pex12 PF04757.9 CCV00693.1 - 2.7e-49 167.6 11.6 4.3e-49 167.0 8.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 CCV00693.1 - 0.0018 17.9 3.1 0.0027 17.3 2.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCV00693.1 - 0.0039 17.1 4.3 0.0062 16.5 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCV00693.1 - 0.042 13.6 5.6 0.096 12.5 3.9 1.6 1 1 1 2 2 2 0 Ring finger domain Thg1C PF14413.1 CCV00694.1 - 1.3e-26 92.6 0.1 7.8e-22 77.2 0.0 2.1 1 1 1 2 2 2 2 Thg1 C terminal domain CG-1 PF03859.11 CCV00694.1 - 0.055 13.0 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 CG-1 domain Nup160 PF11715.3 CCV00695.1 - 0.13 10.3 0.0 0.16 10.0 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 UQ_con PF00179.21 CCV00696.1 - 1.7e-07 30.7 0.0 1.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme STAG PF08514.6 CCV00698.1 - 4.6e-19 68.2 0.4 2.5e-18 65.8 0.1 2.5 2 1 0 2 2 2 1 STAG domain HEAT PF02985.17 CCV00698.1 - 0.0086 16.0 1.2 5.7 7.2 0.0 4.9 3 0 0 3 3 3 1 HEAT repeat Ipi1_N PF12333.3 CCV00699.1 - 5.4e-14 51.9 0.5 6.6e-12 45.2 0.1 3.9 1 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation RIX1 PF08167.7 CCV00699.1 - 0.043 13.5 3.0 0.19 11.4 0.2 2.5 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Transp_cyt_pur PF02133.10 CCV00700.1 - 1e-29 103.3 36.0 1.5e-29 102.8 24.9 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2672 PF10878.3 CCV00700.1 - 0.065 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) Cellulase PF00150.13 CCV00701.1 - 4.5e-18 65.4 4.9 6.9e-18 64.8 3.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LETM1 PF07766.8 CCV00703.1 - 2.1e-88 295.8 1.7 2.1e-88 295.8 1.2 1.7 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.1 CCV00703.1 - 0.00016 21.7 0.1 0.0021 18.1 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 CCV00703.1 - 0.0043 16.6 0.3 0.021 14.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair Syntaxin-6_N PF09177.6 CCV00703.1 - 0.023 15.1 3.1 0.099 13.0 0.0 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal NUC173 PF08161.7 CCV00704.1 - 4.6e-40 137.1 0.0 9.9e-40 136.0 0.0 1.6 1 0 0 1 1 1 1 NUC173 domain Ferric_reduct PF01794.14 CCV00705.1 - 1.3e-13 51.1 11.1 1.3e-13 51.1 7.7 2.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CCV00705.1 - 7.7e-13 48.6 0.0 2.4e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CCV00705.1 - 6.5e-11 42.0 0.0 3.4e-10 39.7 0.0 2.2 2 1 0 2 2 2 1 FAD-binding domain Gpi16 PF04113.9 CCV00706.1 - 1e-102 344.0 0.0 1.5e-52 178.4 0.0 2.0 1 1 1 2 2 2 2 Gpi16 subunit, GPI transamidase component Rot1 PF10681.4 CCV00707.1 - 1.5e-53 181.2 5.5 2.1e-53 180.8 3.8 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal GAS2 PF02187.12 CCV00707.1 - 0.0013 18.4 0.4 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain Coatomer_WDAD PF04053.9 CCV00708.1 - 9.8e-126 420.1 0.0 1.7e-125 419.3 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 CCV00708.1 - 5.6e-65 219.5 0.0 8.4e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CCV00708.1 - 1.6e-60 198.9 7.8 1.7e-11 43.5 0.1 8.9 9 0 0 9 9 9 6 WD domain, G-beta repeat Nup160 PF11715.3 CCV00708.1 - 0.00023 19.4 8.1 0.011 13.9 0.1 4.1 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCV00708.1 - 0.096 11.4 3.7 7.9 5.1 0.0 3.6 1 1 2 3 3 3 0 Nup133 N terminal like Mit_ribos_Mrp51 PF11709.3 CCV00709.1 - 7e-15 55.0 0.0 1.8e-14 53.6 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit DMRL_synthase PF00885.14 CCV00710.1 - 1.4e-46 157.7 0.0 1.5e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase ECH_C PF13766.1 CCV00711.1 - 7.3e-19 68.0 0.0 3.3e-18 65.9 0.0 2.1 1 1 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CCV00711.1 - 7.9e-16 57.9 0.1 1.1e-14 54.2 0.1 2.2 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family tRNA-synt_2 PF00152.15 CCV00712.1 - 1e-29 103.3 0.0 1.4e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCV00712.1 - 9.6e-06 25.3 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain D123 PF07065.9 CCV00713.1 - 2.1e-72 243.7 0.0 2.4e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 CCV00713.1 - 0.043 13.6 0.1 0.17 11.7 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4343) RRM_1 PF00076.17 CCV00714.1 - 1.3e-12 47.1 0.1 4.3e-12 45.4 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCV00714.1 - 7.1e-11 41.9 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCV00714.1 - 2.7e-06 27.1 0.0 5.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAC PF01849.13 CCV00715.1 - 1.3e-19 69.4 0.1 2.2e-19 68.7 0.1 1.4 1 0 0 1 1 1 1 NAC domain ATP-synt_E PF05680.7 CCV00716.1 - 2.3e-20 72.3 2.3 4e-20 71.5 1.6 1.5 1 1 0 1 1 1 1 ATP synthase E chain AIF-MLS PF14962.1 CCV00716.1 - 0.028 14.0 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF2048 PF09752.4 CCV00716.1 - 0.035 12.9 0.0 0.038 12.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) AMP-binding PF00501.23 CCV00717.1 - 3.7e-93 312.1 0.1 4.5e-93 311.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCV00717.1 - 2.6e-19 69.9 0.3 2.1e-18 67.0 0.0 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain She9_MDM33 PF05546.6 CCV00718.1 - 5.5e-53 179.6 6.5 7.5e-53 179.1 4.5 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family DUF904 PF06005.7 CCV00718.1 - 1.1 9.5 7.7 0.14 12.4 1.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF2043 PF09740.4 CCV00718.1 - 1.4 9.0 4.4 0.54 10.3 0.6 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2043) ABC_tran PF00005.22 CCV00719.1 - 2.2e-42 144.6 0.0 3.7e-21 75.8 0.0 4.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCV00719.1 - 2e-16 60.8 0.4 0.00018 21.5 0.0 4.4 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 CCV00719.1 - 1e-12 47.7 0.7 0.021 14.0 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCV00719.1 - 2.3e-09 36.6 0.3 0.00085 18.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain CLASP_N PF12348.3 CCV00719.1 - 1.7e-07 30.8 0.0 0.0074 15.6 0.0 2.7 1 1 1 2 2 2 2 CLASP N terminal AAA_22 PF13401.1 CCV00719.1 - 3.8e-07 30.2 0.0 0.032 14.3 0.0 4.6 5 0 0 5 5 4 2 AAA domain HEAT_2 PF13646.1 CCV00719.1 - 2e-06 28.0 0.9 0.11 12.8 0.0 4.5 4 1 1 5 5 4 2 HEAT repeats AAA_17 PF13207.1 CCV00719.1 - 3.8e-06 27.7 0.4 0.15 12.8 0.0 3.7 4 0 0 4 4 2 2 AAA domain HEAT_EZ PF13513.1 CCV00719.1 - 5.7e-06 26.6 0.6 4.1 8.0 0.0 6.1 5 2 2 7 7 6 0 HEAT-like repeat AAA_23 PF13476.1 CCV00719.1 - 6.1e-06 26.7 5.5 0.052 13.8 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 CCV00719.1 - 9.6e-06 25.2 1.3 0.075 12.4 0.0 4.0 3 1 0 4 4 4 2 AAA-like domain Miro PF08477.8 CCV00719.1 - 1.4e-05 25.5 0.0 0.039 14.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 CCV00719.1 - 3.4e-05 23.6 0.4 0.0087 15.9 0.0 3.4 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 CCV00719.1 - 0.00022 20.9 0.5 0.63 9.6 0.0 3.2 3 1 0 3 3 3 2 NACHT domain FtsK_SpoIIIE PF01580.13 CCV00719.1 - 0.00029 20.3 0.1 2.5 7.5 0.0 3.5 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_33 PF13671.1 CCV00719.1 - 0.00038 20.3 0.0 0.72 9.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCV00719.1 - 0.00041 19.5 0.0 0.37 9.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 CCV00719.1 - 0.00058 19.5 0.1 0.61 9.7 0.1 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CCV00719.1 - 0.0011 19.3 0.0 0.86 9.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CCV00719.1 - 0.0014 18.5 0.0 1.2 9.0 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Chromo PF00385.19 CCV00719.1 - 0.0017 17.9 0.1 0.0063 16.1 0.0 2.1 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.24 CCV00719.1 - 0.0019 18.3 0.0 2.1 8.5 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCV00719.1 - 0.0023 17.9 5.4 0.21 11.5 0.8 4.3 3 1 0 3 3 3 1 AAA ATPase domain ArgK PF03308.11 CCV00719.1 - 0.0025 16.6 0.2 0.51 9.0 0.0 2.7 2 0 0 2 2 2 1 ArgK protein AAA_28 PF13521.1 CCV00719.1 - 0.0031 17.4 0.0 4 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CCV00719.1 - 0.0031 16.9 0.0 4.4 6.6 0.0 3.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 CCV00719.1 - 0.0034 17.5 0.0 5.1 7.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 CCV00719.1 - 0.0042 15.9 0.1 2.1 7.1 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain AAA_15 PF13175.1 CCV00719.1 - 0.006 15.6 0.0 6.1 5.7 0.0 3.7 4 0 0 4 4 4 0 AAA ATPase domain AAA_30 PF13604.1 CCV00719.1 - 0.0066 16.0 0.0 6.8 6.2 0.0 3.3 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 CCV00719.1 - 0.0069 16.2 6.3 0.18 11.5 0.0 3.8 4 0 0 4 4 3 1 Domain of unknown function DUF87 AAA_14 PF13173.1 CCV00719.1 - 0.018 14.9 0.0 13 5.7 0.0 4.2 4 2 0 4 4 3 0 AAA domain UME PF08064.8 CCV00719.1 - 0.039 13.8 0.5 0.11 12.4 0.3 1.8 1 0 0 1 1 1 0 UME (NUC010) domain Arch_ATPase PF01637.13 CCV00719.1 - 0.057 13.0 4.7 3.9 7.0 0.1 4.0 4 1 0 4 4 3 0 Archaeal ATPase ATP_bind_1 PF03029.12 CCV00719.1 - 0.06 12.8 0.3 4.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 CCV00719.1 - 0.13 12.0 0.7 4 7.2 0.0 2.9 3 0 0 3 3 2 0 Dynamin family G-alpha PF00503.15 CCV00719.1 - 0.16 10.6 4.5 1.4 7.5 0.0 2.6 3 0 0 3 3 2 0 G-protein alpha subunit AAA_5 PF07728.9 CCV00719.1 - 0.28 10.9 2.3 24 4.6 0.0 4.1 5 0 0 5 5 3 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 CCV00719.1 - 0.45 8.9 7.1 1.1 7.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain DUF1227 PF06777.6 CCV00720.1 - 6.2e-60 201.1 0.3 1.3e-59 200.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 CCV00720.1 - 2e-45 154.7 0.0 4e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CCV00720.1 - 1e-06 28.2 0.6 1.9e-06 27.3 0.1 1.7 2 0 0 2 2 2 1 DEAD_2 YtxC PF08812.6 CCV00720.1 - 0.17 11.3 2.8 0.23 10.9 0.0 2.4 3 0 0 3 3 3 0 YtxC-like family SNF2_N PF00176.18 CCV00721.1 - 1.8e-67 227.2 0.0 2.3e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCV00721.1 - 3.9e-16 58.6 0.1 1.3e-14 53.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CCV00721.1 - 0.0003 19.7 0.0 0.001 17.9 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CCV00721.1 - 0.0022 17.4 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CCV00721.1 - 0.032 14.0 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sec2p PF06428.6 CCV00722.1 - 5.6e-16 58.2 9.2 5.6e-16 58.2 6.4 2.6 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Pterin_bind PF00809.17 CCV00725.1 - 1.3e-60 204.4 0.0 2.4e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 CCV00725.1 - 1.8e-40 137.6 0.0 3.5e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 CCV00725.1 - 4.4e-39 133.1 0.0 2.7e-22 79.0 0.0 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase Serinc PF03348.10 CCV00726.1 - 2e-123 412.3 4.0 2.6e-123 411.9 2.8 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) GTP1_OBG PF01018.17 CCV00727.1 - 2e-33 115.2 2.7 1.8e-25 89.4 1.7 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 CCV00727.1 - 1e-17 64.1 0.0 1.7e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCV00727.1 - 3.3e-08 32.9 0.0 1.1e-06 28.0 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CCV00727.1 - 2.2e-05 23.9 0.0 0.0037 16.7 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.16 CCV00727.1 - 0.0047 16.1 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family ArgK PF03308.11 CCV00727.1 - 0.0071 15.1 0.0 0.92 8.2 0.0 2.3 2 0 0 2 2 2 2 ArgK protein Dynamin_N PF00350.18 CCV00727.1 - 0.026 14.3 0.0 2.1 8.1 0.0 2.3 1 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.22 CCV00727.1 - 0.039 14.2 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Fe-S_biosyn PF01521.15 CCV00728.1 - 3e-18 65.8 0.0 3.7e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis tRNA-synt_2c PF01411.14 CCV00729.1 - 6.9e-212 704.5 0.0 8.7e-212 704.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CCV00729.1 - 2.3e-15 56.1 0.1 5.4e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CCV00729.1 - 2.4e-06 27.1 0.1 7e-06 25.6 0.1 1.9 1 0 0 1 1 1 1 DHHA1 domain zf-C2H2 PF00096.21 CCV00730.1 - 8e-12 44.7 18.9 1.7e-05 24.8 0.5 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCV00730.1 - 7.1e-07 29.2 19.8 0.0017 18.5 0.0 4.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCV00730.1 - 9.3e-07 28.7 25.3 0.0012 18.9 0.4 4.8 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCV00730.1 - 4.6e-05 23.1 1.5 0.068 13.0 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CCV00730.1 - 0.00014 21.9 1.8 0.054 13.7 0.1 3.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCV00730.1 - 0.024 14.8 0.2 8.3 6.6 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 CCV00730.1 - 0.061 13.0 6.5 1.4 8.6 0.1 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 CCV00730.1 - 5.7 6.9 7.4 4.9 7.1 0.2 3.3 3 0 0 3 3 3 0 Zinc ribbon domain adh_short PF00106.20 CCV00731.1 - 9.2e-15 54.9 0.8 1.4e-14 54.3 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCV00731.1 - 4.7e-07 29.6 2.2 2.3e-06 27.4 1.5 1.9 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CCV00731.1 - 4.5e-06 26.4 0.1 7.4e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCV00731.1 - 3.6e-05 23.8 0.2 0.12 12.3 0.0 2.3 1 1 1 2 2 2 2 NADH(P)-binding F420_oxidored PF03807.12 CCV00731.1 - 0.055 13.8 0.1 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.1 CCV00731.1 - 0.058 13.1 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Helicase_RecD PF05127.9 CCV00731.1 - 0.08 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase ADH_zinc_N PF00107.21 CCV00731.1 - 0.28 10.7 1.8 0.38 10.3 0.3 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Asp PF00026.18 CCV00732.1 - 1.2e-44 152.8 2.4 3.3e-44 151.4 1.7 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCV00732.1 - 2.8e-06 27.7 0.1 0.15 12.5 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 CCV00732.1 - 0.0076 16.2 0.3 0.22 11.4 0.1 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCV00732.1 - 0.032 13.7 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Mitofilin PF09731.4 CCV00735.1 - 6.7e-104 348.6 24.9 7.8e-104 348.4 17.3 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Apolipoprotein PF01442.13 CCV00735.1 - 0.00013 21.5 3.2 0.00013 21.5 2.2 2.7 1 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 CCV00735.1 - 0.034 14.5 1.7 0.034 14.5 1.2 6.1 3 2 4 7 7 7 0 Bacterial protein of unknown function (DUF883) XH PF03469.9 CCV00735.1 - 0.65 9.6 7.8 0.35 10.5 1.2 3.0 3 1 0 3 3 3 0 XH domain Fzo_mitofusin PF04799.8 CCV00735.1 - 1.2 8.4 11.5 0.055 12.8 0.4 2.8 2 1 0 3 3 3 0 fzo-like conserved region Flagellin_N PF00669.15 CCV00735.1 - 6.6 6.5 19.2 2 8.2 1.5 4.3 4 0 0 4 4 4 0 Bacterial flagellin N-terminal helical region DHBP_synthase PF00926.14 CCV00736.1 - 3.2e-75 251.6 0.0 3.5e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase ATP-synt_ab PF00006.20 CCV00737.1 - 2.1e-110 367.3 0.0 2.8e-110 366.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCV00737.1 - 2.8e-22 79.3 0.1 5.7e-22 78.3 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCV00737.1 - 4.5e-13 49.1 1.7 1.4e-12 47.6 1.2 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.24 CCV00738.1 - 1.7e-40 138.2 0.0 3.2e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCV00738.1 - 1e-05 25.6 0.0 0.001 19.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCV00738.1 - 3.2e-05 23.6 0.1 0.00018 21.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCV00738.1 - 0.00044 20.2 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CCV00738.1 - 0.00064 18.7 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CCV00738.1 - 0.0012 18.8 0.0 0.0074 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CCV00738.1 - 0.0029 18.4 0.1 0.0074 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCV00738.1 - 0.0055 16.4 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CCV00738.1 - 0.0074 15.3 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CCV00738.1 - 0.0088 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCV00738.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CCV00738.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF4164 PF13747.1 CCV00738.1 - 0.019 15.0 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) IstB_IS21 PF01695.12 CCV00738.1 - 0.021 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 CCV00738.1 - 0.029 14.4 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 CCV00738.1 - 0.03 14.0 0.0 3.3 7.3 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_3 PF07726.6 CCV00738.1 - 0.044 13.3 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CCV00738.1 - 0.048 13.0 0.3 0.25 10.7 0.1 2.2 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CCV00738.1 - 0.049 12.8 0.0 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 CCV00738.1 - 0.049 12.3 0.0 0.093 11.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 CCV00738.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CCV00738.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CCV00738.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4187 PF13821.1 CCV00739.1 - 2.2e-17 62.3 0.2 4.5e-17 61.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 CCV00739.1 - 6.4e-05 22.6 0.0 0.00031 20.4 0.0 2.0 2 0 0 2 2 2 1 G-patch domain zf-C2H2_jaz PF12171.3 CCV00739.1 - 0.13 12.3 1.5 0.26 11.4 1.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CCV00739.1 - 0.14 12.5 0.3 0.31 11.4 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger PRP1_N PF06424.7 CCV00739.1 - 3.1 8.1 10.3 0.26 11.6 2.3 2.5 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal Thiolase_N PF00108.18 CCV00740.1 - 4.9e-92 307.6 2.1 7.5e-92 307.0 1.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCV00740.1 - 9.2e-39 131.6 1.6 9.2e-39 131.6 1.1 2.2 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCV00740.1 - 4.9e-05 22.9 5.2 4.9e-05 22.9 3.6 3.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CCV00740.1 - 0.0014 18.2 5.4 0.0049 16.5 0.1 3.1 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Abhydrolase_5 PF12695.2 CCV00740.1 - 0.13 12.0 1.6 0.71 9.6 0.1 2.7 2 2 0 2 2 2 0 Alpha/beta hydrolase family UQ_con PF00179.21 CCV00741.1 - 3.7e-19 68.5 0.0 4.2e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCV00741.1 - 0.019 14.8 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain ECR1_N PF14382.1 CCV00742.1 - 3.6e-07 29.3 0.0 6.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 CCV00742.1 - 3.4e-06 26.9 0.0 3.5e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 CCV00742.1 - 0.025 14.6 0.0 0.32 11.1 0.0 2.3 2 0 0 2 2 2 0 S1 RNA binding domain MIF4G PF02854.14 CCV00743.1 - 3e-29 101.9 0.2 6.9e-28 97.4 0.0 2.5 2 1 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CCV00743.1 - 2.4e-27 94.8 0.2 4.8e-27 93.9 0.1 1.5 1 0 0 1 1 1 1 MA3 domain Actin PF00022.14 CCV00745.1 - 1.4e-39 135.7 0.0 3.2e-26 91.6 0.0 2.1 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 CCV00745.1 - 0.023 13.3 0.0 0.042 12.4 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein SYF2 PF08231.7 CCV00746.1 - 1.5e-38 132.3 11.5 1.5e-38 132.3 8.0 1.7 2 0 0 2 2 2 1 SYF2 splicing factor Nipped-B_C PF12830.2 CCV00748.1 - 0.073 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Abhydrolase_3 PF07859.8 CCV00749.1 - 3.3e-41 141.1 0.1 9.8e-32 110.2 0.0 3.0 2 1 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CCV00749.1 - 4.8e-08 32.0 0.0 2.1e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CCV00749.1 - 0.0014 18.4 0.0 0.0029 17.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 CCV00749.1 - 0.013 14.0 0.0 0.021 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) COesterase PF00135.23 CCV00749.1 - 0.028 13.1 0.3 0.65 8.6 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family FAD_binding_6 PF00970.19 CCV00750.1 - 1.9e-25 88.8 0.0 2.9e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CCV00750.1 - 4.7e-25 88.2 0.0 2.2e-24 86.0 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CCV00750.1 - 8.6e-05 22.4 0.0 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain ATP_synt_H PF05493.8 CCV00750.1 - 0.0084 16.1 1.3 0.015 15.3 0.1 1.9 2 0 0 2 2 2 1 ATP synthase subunit H AlaDh_PNT_N PF05222.10 CCV00751.1 - 2.1e-27 95.7 0.0 3.7e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CCV00751.1 - 7.6e-07 28.8 0.0 2.8e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Mog1 PF04603.7 CCV00752.1 - 3.7e-26 91.7 0.1 4.6e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein WD40 PF00400.27 CCV00753.1 - 2.7e-20 71.4 2.5 4e-06 26.5 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 CCV00753.1 - 0.058 13.0 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCV00753.1 - 0.15 10.1 0.3 1.3 7.0 0.0 2.0 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Asn_synthase PF00733.16 CCV00754.1 - 2.6e-68 230.2 0.1 5.7e-68 229.1 0.1 1.6 2 0 0 2 2 2 1 Asparagine synthase GATase_7 PF13537.1 CCV00754.1 - 1.5e-38 131.3 0.0 2.4e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CCV00754.1 - 1e-31 109.6 0.0 4.4e-31 107.5 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CCV00754.1 - 1.3e-07 30.6 0.0 0.061 12.0 0.0 3.1 1 1 2 3 3 3 3 Glutamine amidotransferases class-II DUF3700 PF12481.3 CCV00754.1 - 1.1e-06 28.0 0.0 1.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 CCV00754.1 - 0.0023 16.8 0.0 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD synthase Pam16 PF03656.8 CCV00755.1 - 2.6e-15 56.3 0.2 5.4e-15 55.3 0.2 1.5 1 1 0 1 1 1 1 Pam16 Borrelia_P83 PF05262.6 CCV00756.1 - 0.5 8.5 8.0 0.53 8.4 5.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ycf1 PF05758.7 CCV00756.1 - 0.62 7.7 2.6 0.72 7.5 1.8 1.0 1 0 0 1 1 1 0 Ycf1 DUF4603 PF15376.1 CCV00756.1 - 2.3 5.2 7.0 2.6 5.1 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) FYVE PF01363.16 CCV00758.1 - 1.9 8.4 7.1 4.7 7.1 4.9 1.6 1 1 0 1 1 1 0 FYVE zinc finger Ras PF00071.17 CCV00759.1 - 3.9e-33 114.1 0.0 4.5e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCV00759.1 - 4.1e-06 27.2 0.0 5.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein tRNA_Me_trans PF03054.11 CCV00761.1 - 2.3e-91 305.9 0.0 2.6e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase CENP-C_C PF11699.3 CCV00762.1 - 8.8e-11 41.6 0.0 9.1e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Mif2/CENP-C like Mif2_N PF15624.1 CCV00762.1 - 0.00014 22.4 0.4 0.00083 19.9 0.0 2.4 1 1 1 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal FAD_binding_7 PF03441.9 CCV00765.1 - 4.6e-91 304.8 5.6 5.4e-91 304.6 3.1 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CCV00765.1 - 1.1e-33 116.3 0.0 3.8e-33 114.5 0.0 1.9 2 0 0 2 2 2 1 DNA photolyase 2OG-FeII_Oxy PF03171.15 CCV00766.1 - 3.5e-16 59.2 0.0 5.6e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CCV00766.1 - 8.7e-09 35.9 0.0 5.6e-05 23.6 0.0 2.3 1 1 1 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.11 CCV00767.1 - 1e-29 103.3 68.2 9.9e-28 96.8 29.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M50 PF02163.17 CCV00767.1 - 0.97 8.3 4.7 15 4.4 1.9 2.4 2 1 0 2 2 2 0 Peptidase family M50 GMC_oxred_N PF00732.14 CCV00768.1 - 5.3e-49 166.9 0.0 7.3e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCV00768.1 - 5.5e-27 94.8 0.0 1.2e-26 93.7 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CCV00768.1 - 4.4e-06 25.8 0.1 0.0052 15.6 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CCV00768.1 - 5.8e-05 23.0 0.0 0.00017 21.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCV00768.1 - 5.9e-05 22.1 1.7 0.0019 17.2 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCV00768.1 - 0.00084 19.2 0.2 0.025 14.4 0.0 2.5 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCV00768.1 - 0.0053 15.7 0.0 0.0092 14.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 CCV00768.1 - 0.0068 15.5 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Endotoxin_mid PF09131.5 CCV00768.1 - 0.017 14.5 0.1 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis delta-Endotoxin, middle domain NAD_binding_9 PF13454.1 CCV00768.1 - 0.076 12.7 0.2 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 CCV00768.1 - 0.078 11.4 0.1 0.3 9.5 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_43 PF04616.9 CCV00769.1 - 9.8e-40 136.4 0.0 8.4e-38 130.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 ADH_zinc_N PF00107.21 CCV00769.1 - 5.5e-28 97.0 0.0 1.2e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCV00769.1 - 1.9e-12 46.9 0.0 6.9e-12 45.0 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CCV00769.1 - 2.4e-07 31.6 0.2 6.8e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CCV00769.1 - 0.03 14.3 0.1 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding AA_kinase PF00696.23 CCV00770.1 - 1.7e-34 119.4 0.0 4.8e-34 117.9 0.0 1.7 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 CCV00770.1 - 1.1e-09 37.5 0.2 0.00016 21.0 0.0 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 CCV00770.1 - 1.8e-09 36.9 1.5 4.2e-06 26.1 0.2 2.6 2 0 0 2 2 2 2 ACT domain Cse1 PF08506.5 CCV00771.1 - 9e-127 422.6 0.0 1.5e-126 421.9 0.0 1.4 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 CCV00771.1 - 1.3e-117 392.7 0.0 2.4e-117 391.9 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 CCV00771.1 - 1.5e-15 56.8 1.8 2.3e-14 53.0 0.2 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CCV00771.1 - 0.00044 20.1 5.5 0.0041 17.0 0.2 4.8 5 2 2 7 7 7 1 Exportin 1-like protein DUF1678 PF07913.6 CCV00771.1 - 0.021 14.4 2.3 4 6.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1678) RNB PF00773.14 CCV00772.1 - 1.2e-31 110.2 0.0 3.3e-21 75.9 0.0 2.3 2 0 0 2 2 2 2 RNB domain OB_RNB PF08206.6 CCV00772.1 - 0.14 11.6 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain NIF PF03031.13 CCV00773.1 - 2.5e-07 30.5 0.0 0.018 14.6 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase ACOX PF01756.14 CCV00774.1 - 3.8e-44 150.2 0.0 5.9e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 CCV00774.1 - 1e-15 56.9 0.7 2.7e-15 55.6 0.5 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CCV00774.1 - 3e-07 30.6 0.0 9.4e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 CCV00774.1 - 6.1e-06 26.5 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Mito_carr PF00153.22 CCV00775.1 - 2.9e-64 212.8 5.4 1e-22 79.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 CCV00775.1 - 0.00016 20.7 0.5 0.0034 16.5 0.1 2.9 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CCV00775.1 - 0.00041 19.9 0.0 0.011 15.5 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 CCV00775.1 - 0.0028 17.2 0.3 0.0093 15.5 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 CCV00775.1 - 0.0033 17.5 0.1 0.015 15.3 0.1 2.1 1 1 0 1 1 1 1 EF-hand domain pair V-ATPase_H_N PF03224.9 CCV00775.1 - 0.15 11.1 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 V-ATPase subunit H Tubulin PF00091.20 CCV00776.1 - 3.3e-69 233.0 0.0 4.5e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCV00776.1 - 3.2e-47 159.6 0.0 5e-47 159.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CCV00776.1 - 0.00054 19.4 0.0 0.0013 18.2 0.0 1.7 1 1 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CCV00776.1 - 0.07 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain SRF-TF PF00319.13 CCV00777.1 - 9.8e-21 72.7 0.0 1.5e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) zf-U1 PF06220.7 CCV00777.1 - 2.6e-07 30.0 1.3 4.9e-07 29.1 0.9 1.5 1 0 0 1 1 1 1 U1 zinc finger Ribosomal_60s PF00428.14 CCV00777.1 - 0.036 14.4 1.8 0.036 14.4 1.2 5.3 3 1 1 5 5 5 0 60s Acidic ribosomal protein CPSF_A PF03178.10 CCV00778.1 - 1.3e-53 182.2 0.0 2.2e-53 181.4 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region Ribosomal_S26e PF01283.14 CCV00779.1 - 5.9e-52 174.7 6.4 6.9e-52 174.5 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF3133 PF11331.3 CCV00779.1 - 0.18 11.4 0.8 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) HC2 PF07382.6 CCV00780.1 - 0.0083 16.0 1.4 0.0083 16.0 1.0 2.6 2 1 0 3 3 3 2 Histone H1-like nucleoprotein HC2 Glyco_hydro_16 PF00722.16 CCV00781.1 - 7.7e-20 70.9 0.0 1.3e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKG6 PF08693.5 CCV00781.1 - 0.061 12.6 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2062 PF09835.4 CCV00781.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Chitin_bind_1 PF00187.14 CCV00781.1 - 0.1 12.5 12.3 0.22 11.5 8.5 1.5 1 0 0 1 1 1 0 Chitin recognition protein Rab5-bind PF09311.6 CCV00782.1 - 0.097 12.5 0.6 0.21 11.4 0.4 1.5 1 0 0 1 1 1 0 Rabaptin-like protein bZIP_1 PF00170.16 CCV00782.1 - 0.21 11.5 7.3 0.24 11.3 0.3 2.5 2 0 0 2 2 2 0 bZIP transcription factor DDHD PF02862.12 CCV00783.1 - 2.9e-19 69.7 0.0 2.6e-16 60.1 0.0 2.4 1 1 0 2 2 2 2 DDHD domain Abhydrolase_5 PF12695.2 CCV00783.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family ADP_PFK_GK PF04587.10 CCV00783.1 - 0.34 9.0 0.0 0.51 8.4 0.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region DUF676 PF05057.9 CCV00786.1 - 0.00033 20.0 0.0 0.00076 18.8 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CCV00786.1 - 0.00045 19.8 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CCV00786.1 - 0.035 13.8 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.10 CCV00786.1 - 0.25 10.2 0.0 0.39 9.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase UCH PF00443.24 CCV00788.1 - 2e-39 135.3 0.0 2.7e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCV00788.1 - 5.5e-12 45.7 0.0 2e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 CCV00788.1 - 7.3e-11 41.3 0.1 5.1e-10 38.6 0.0 2.4 2 0 0 2 2 2 1 A repeated domain in UCH-protein WVELL PF14043.1 CCV00788.1 - 0.095 12.3 0.3 20 4.9 0.0 3.0 3 0 0 3 3 3 0 WVELL protein Rer1 PF03248.8 CCV00789.1 - 1.7e-77 259.0 1.2 2e-77 258.7 0.8 1.0 1 0 0 1 1 1 1 Rer1 family EI24 PF07264.6 CCV00789.1 - 1.3 8.3 12.2 7 6.0 8.5 1.8 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Cupin_8 PF13621.1 CCV00790.1 - 2e-49 168.3 0.0 2.9e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CCV00790.1 - 0.027 13.6 0.5 1.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Cupin superfamily protein Mak16 PF04874.9 CCV00790.1 - 0.28 11.2 8.5 0.52 10.4 4.9 1.9 2 0 0 2 2 2 0 Mak16 protein C-terminal region Nop14 PF04147.7 CCV00790.1 - 0.54 8.1 4.8 0.69 7.7 3.4 1.1 1 0 0 1 1 1 0 Nop14-like family LIP PF03583.9 CCV00791.1 - 3.7e-66 223.2 0.0 5.4e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 CCV00791.1 - 2.8e-05 23.8 0.5 0.00033 20.4 0.4 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCV00791.1 - 0.037 13.9 2.5 0.36 10.6 1.7 2.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCV00791.1 - 0.044 13.2 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CCV00791.1 - 0.11 11.7 4.2 2 7.5 0.0 2.8 2 1 1 3 3 3 0 Prolyl oligopeptidase family LIP PF03583.9 CCV00792.1 - 3.5e-63 213.5 0.0 4.7e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 CCV00792.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCV00792.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Cu_amine_oxid PF01179.15 CCV00793.1 - 2.2e-163 543.8 0.0 2.6e-163 543.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 CCV00793.1 - 1.3e-08 34.7 0.0 6.8e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain PAP_assoc PF03828.14 CCV00797.1 - 3.1e-15 55.8 0.0 6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CCV00797.1 - 8.9e-08 32.3 0.0 1.8e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain CBS PF00571.23 CCV00798.1 - 1.8e-10 40.4 0.0 2.4e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 CBS domain TFIID_30kDa PF03540.8 CCV00798.1 - 1e-09 38.0 0.0 2.9e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Peptidase_M13_N PF05649.8 CCV00800.1 - 5.8e-82 275.8 0.0 7.6e-82 275.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 CCV00800.1 - 2.5e-56 190.1 0.0 7e-56 188.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M13 Orexin PF02072.10 CCV00800.1 - 0.038 13.7 0.2 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Prepro-orexin Helicase_C PF00271.26 CCV00801.1 - 2e-14 53.2 0.0 3.9e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 CCV00801.1 - 1.2e-10 41.2 0.1 3.3e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 CCV00801.1 - 8.6e-10 38.3 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 CCV00801.1 - 4.6e-09 36.1 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 CCV00801.1 - 0.00039 20.5 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CCV00801.1 - 0.00094 18.3 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 KaiC T2SE PF00437.15 CCV00801.1 - 0.0059 15.5 0.0 0.013 14.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 CCV00801.1 - 0.03 13.4 0.1 0.43 9.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 CCV00801.1 - 0.076 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.10 CCV00801.1 - 0.094 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ResIII PF04851.10 CCV00801.1 - 0.1 12.4 0.0 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 CCV00801.1 - 0.13 11.8 0.0 0.46 10.1 0.0 2.0 1 0 0 1 1 1 0 NACHT domain RINGv PF12906.2 CCV00807.1 - 2.1e-12 46.9 4.9 3.3e-12 46.2 3.4 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CCV00807.1 - 0.075 12.8 3.7 0.14 12.0 2.5 1.4 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 CCV00807.1 - 0.4 10.6 2.1 0.65 10.0 1.4 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain